# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Scs3p PF10261.4 EMG45163.1 - 5.5e-75 251.4 15.7 6.9e-75 251.1 10.9 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.16 EMG45163.1 - 0.53 9.9 8.4 0.039 13.6 1.5 2.2 2 0 0 2 2 2 0 PAP2 superfamily Dynamin_N PF00350.18 EMG45164.1 - 2.2e-14 53.6 4.1 1.6e-13 50.8 0.0 3.8 3 2 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 EMG45164.1 - 1.1e-07 31.5 2.2 1.4e-06 27.8 0.4 3.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMG45164.1 - 3.1e-07 30.3 6.3 3.6e-07 30.1 0.0 4.0 4 3 1 5 5 5 1 50S ribosome-binding GTPase Miro PF08477.8 EMG45164.1 - 0.0029 18.0 0.3 0.85 10.1 0.2 3.5 2 1 0 2 2 2 1 Miro-like protein PglZ PF08665.7 EMG45164.1 - 0.067 12.8 0.2 0.067 12.8 0.1 3.6 4 0 0 4 4 4 0 PglZ domain AAA_18 PF13238.1 EMG45164.1 - 6.9 6.9 9.5 8.5 6.6 0.0 4.3 6 0 0 6 6 6 0 AAA domain Ureidogly_hydro PF04115.7 EMG45165.1 - 1.2e-50 171.0 0.1 1.4e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase Sec15 PF04091.7 EMG45166.1 - 4e-73 246.4 17.0 6.2e-54 183.4 1.1 3.9 2 2 2 4 4 4 2 Exocyst complex subunit Sec15-like CtaG_Cox11 PF04442.9 EMG45166.1 - 9e-56 187.8 0.7 3.4e-55 186.0 0.0 2.3 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein CtaG/Cox11 BATS PF06968.8 EMG45167.1 - 1.2e-28 98.7 0.0 2.9e-28 97.5 0.0 1.7 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EMG45167.1 - 2e-17 63.8 0.4 4.5e-17 62.7 0.1 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Orn_Arg_deC_N PF02784.11 EMG45167.1 - 0.00058 19.1 0.1 0.00083 18.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Ribosomal_L22e PF01776.12 EMG45168.1 - 1.1e-42 144.4 3.5 1.3e-42 144.3 2.5 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Oxidored_q1 PF00361.15 EMG45169.1 - 4.5e-28 98.2 8.8 4.5e-28 98.2 6.1 1.4 2 0 0 2 2 2 1 NADH-Ubiquinone/plastoquinone (complex I), various chains ABC2_membrane_3 PF12698.2 EMG45174.1 - 0.014 14.4 0.6 0.015 14.3 0.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein SH3_9 PF14604.1 EMG45176.1 - 2.1e-10 40.0 0.0 4.9e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PX PF00787.19 EMG45176.1 - 1.3e-07 31.3 1.4 1.3e-07 31.3 1.0 2.6 3 0 0 3 3 3 1 PX domain SH3_1 PF00018.23 EMG45176.1 - 1.4e-07 30.8 0.0 2.9e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMG45176.1 - 0.00026 20.4 0.0 0.00068 19.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain UNC-79 PF14776.1 EMG45176.1 - 0.0055 15.1 0.9 0.0055 15.1 0.6 1.6 2 0 0 2 2 2 1 Cation-channel complex subunit UNC-79 DNA_ligase_A_M PF01068.16 EMG45177.1 - 2.4e-56 190.3 1.0 4.2e-56 189.5 0.7 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EMG45177.1 - 2.1e-51 174.2 0.6 4.7e-51 173.0 0.4 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EMG45177.1 - 9.8e-25 86.7 0.0 3.3e-24 85.1 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 EMG45177.1 - 0.0024 17.5 1.0 0.27 10.9 0.0 2.8 3 0 0 3 3 3 1 DNA ligase OB-like domain mRNA_cap_enzyme PF01331.14 EMG45177.1 - 0.025 14.2 0.3 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain ORC6 PF05460.8 EMG45177.1 - 0.11 11.5 12.2 0.19 10.7 8.4 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Acyltransferase PF01553.16 EMG45178.1 - 2.5e-09 36.6 0.0 1.8e-08 33.9 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase HIG_1_N PF04588.8 EMG45179.1 - 1.5e-05 24.6 1.1 3.4e-05 23.4 0.8 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region COX16 PF14138.1 EMG45180.1 - 1.2e-23 83.0 2.0 1.4e-23 82.8 1.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 rve PF00665.21 EMG45183.1 - 2e-19 69.8 0.1 4.8e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EMG45183.1 - 1.3e-16 60.5 1.9 4.4e-16 58.8 0.8 2.2 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3552 PF12072.3 EMG45183.1 - 0.00019 20.7 14.9 0.00038 19.7 10.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Terminase_4 PF05119.7 EMG45183.1 - 0.0095 16.0 0.2 0.89 9.7 0.0 3.5 3 0 0 3 3 3 1 Phage terminase, small subunit APG6 PF04111.7 EMG45183.1 - 3.3 6.6 19.9 1.9 7.4 12.2 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 PTR2 PF00854.16 EMG45184.1 - 1.1e-54 185.7 9.1 2e-54 184.8 2.3 2.0 1 1 1 2 2 2 2 POT family PUCC PF03209.10 EMG45184.1 - 0.028 13.1 0.1 0.028 13.1 0.0 1.6 2 0 0 2 2 2 0 PUCC protein DUF2207 PF09972.4 EMG45184.1 - 0.044 12.3 0.2 0.044 12.3 0.1 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF4231 PF14015.1 EMG45184.1 - 0.084 12.8 3.3 0.12 12.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF204 PF02659.10 EMG45184.1 - 0.99 9.5 12.9 0.59 10.3 2.1 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF PTR2 PF00854.16 EMG45185.1 - 1.4e-57 195.1 7.6 2.1e-57 194.5 5.2 1.2 1 0 0 1 1 1 1 POT family RVT_2 PF07727.9 EMG45189.1 - 1.3e-66 224.1 0.0 2.8e-66 223.0 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) COX2 PF00116.15 EMG45190.1 - 7.8e-42 141.8 0.0 9e-42 141.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain NADHdh PF00146.16 EMG45191.1 - 6e-25 87.9 2.1 6e-25 87.9 1.4 1.4 2 0 0 2 2 2 1 NADH dehydrogenase Tetraspannin PF00335.15 EMG45191.1 - 1.3 8.2 4.0 2.2 7.5 2.8 1.4 1 0 0 1 1 1 0 Tetraspanin family Claudin_3 PF06653.6 EMG45191.1 - 2.6 7.7 6.7 3.4 7.3 4.4 1.7 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DEAD PF00270.24 EMG45192.1 - 1.8e-05 24.2 0.0 0.00017 21.1 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG45192.1 - 0.0012 18.6 0.6 0.0059 16.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC4 PF02732.10 EMG45192.1 - 0.036 13.8 0.6 0.12 12.0 0.1 2.2 2 0 0 2 2 2 0 ERCC4 domain RVT_2 PF07727.9 EMG45193.1 - 5.9e-77 257.9 0.0 9.4e-77 257.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EMG45193.1 - 1.6e-15 57.2 0.1 6.6e-15 55.2 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EMG45193.1 - 0.0067 15.8 0.0 0.021 14.2 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_3 PF13917.1 EMG45193.1 - 0.099 12.3 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF1689 PF07954.6 EMG45194.1 - 4.9e-38 130.3 0.5 6.4e-38 129.9 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) BCSC_C PF05420.6 EMG45194.1 - 0.054 12.6 0.2 0.075 12.1 0.1 1.1 1 0 0 1 1 1 0 Cellulose synthase operon protein C C-terminus (BCSC_C) tRNA-synt_2b PF00587.20 EMG45195.1 - 5.7e-40 136.7 0.4 5.8e-24 84.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMG45195.1 - 4.8e-16 58.4 0.1 1.1e-15 57.3 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EMG45195.1 - 6.4e-11 41.9 0.0 1.3e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain LAGLIDADG_3 PF14528.1 EMG45195.1 - 0.055 13.7 0.0 13 6.1 0.0 2.6 2 0 0 2 2 2 0 LAGLIDADG-like domain tRNA-synt_His PF13393.1 EMG45195.1 - 0.14 11.1 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Sugar_tr PF00083.19 EMG45196.1 - 6.8e-45 153.4 2.6 9e-45 153.0 1.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG45196.1 - 1.6e-19 69.8 0.2 1.8e-19 69.6 0.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EMG45196.1 - 0.00032 19.0 0.2 0.00042 18.6 0.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EMG45196.1 - 0.0043 15.5 2.8 0.0043 15.5 1.9 1.9 1 1 0 1 1 1 1 MFS/sugar transport protein ETRAMP PF09716.5 EMG45196.1 - 0.8 9.7 5.3 0.26 11.2 0.4 2.5 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Sugar_tr PF00083.19 EMG45197.1 - 2e-79 267.2 17.8 2.5e-79 266.9 12.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG45197.1 - 1.4e-23 83.2 15.9 4.1e-20 71.8 1.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMG45197.1 - 0.00018 19.8 0.9 0.00018 19.8 0.6 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) WD40 PF00400.27 EMG45199.1 - 2.8e-19 68.1 10.2 1.2e-07 31.2 0.7 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat GTP_EFTU PF00009.22 EMG45200.1 - 3.7e-58 196.0 0.1 7.2e-58 195.1 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EMG45200.1 - 3.8e-37 126.4 0.1 1.1e-36 124.9 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EMG45200.1 - 3.3e-16 59.1 2.5 3.3e-16 59.1 1.7 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EMG45200.1 - 0.00025 20.6 0.9 0.00025 20.6 0.6 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EMG45200.1 - 0.00077 19.3 0.3 0.0026 17.7 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Sugar_tr PF00083.19 EMG45202.1 - 6.7e-89 298.5 27.4 1e-88 297.9 19.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG45202.1 - 9.8e-18 63.9 44.7 1.8e-13 49.9 13.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Thiolase_N PF00108.18 EMG45203.1 - 2.7e-78 262.5 0.0 2.3e-77 259.5 0.0 2.0 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMG45203.1 - 5.7e-45 151.7 0.2 1.3e-44 150.5 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EMG45203.1 - 0.00028 20.4 0.0 0.00067 19.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Apc9 PF12856.2 EMG45203.1 - 0.027 14.5 1.7 0.043 13.8 1.2 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 Sigma70_ner PF04546.8 EMG45203.1 - 0.086 12.4 2.9 0.14 11.8 2.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 EMG45203.1 - 0.93 9.8 5.9 1.5 9.1 4.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PilJ PF13675.1 EMG45204.1 - 0.02 15.2 0.8 0.75 10.1 0.0 2.2 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DM13 PF10517.4 EMG45204.1 - 0.027 14.8 0.0 0.044 14.1 0.0 1.3 1 0 0 1 1 1 0 Electron transfer DM13 NDT80_PhoG PF05224.7 EMG45205.1 - 1.6e-20 73.8 1.3 4.5e-20 72.4 0.0 2.2 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family COPI_C PF06957.6 EMG45205.1 - 0.33 9.4 4.4 0.51 8.8 3.1 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Thiolase_N PF00108.18 EMG45206.1 - 4.3e-89 297.9 0.3 6e-89 297.5 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMG45206.1 - 5.2e-46 155.0 0.0 1.1e-45 154.0 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EMG45206.1 - 0.00066 19.2 0.5 0.0018 17.7 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EMG45206.1 - 0.016 14.8 0.1 0.14 11.7 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF2802 PF10975.3 EMG45206.1 - 0.089 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) HHH_8 PF14716.1 EMG45206.1 - 0.1 12.7 0.6 0.37 10.9 0.2 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain SurE PF01975.12 EMG45208.1 - 2.1e-43 147.9 0.0 2.6e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Sec7_N PF12783.2 EMG45209.1 - 1.4e-42 144.9 7.4 1.4e-42 144.9 5.1 2.7 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal SSF PF00474.12 EMG45210.1 - 6.7e-21 74.3 24.7 1.2e-20 73.5 17.1 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family DDE_3 PF13358.1 EMG45211.1 - 2e-16 60.0 0.5 9.9e-07 28.6 0.0 3.6 4 0 0 4 4 4 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EMG45211.1 - 2.1e-06 27.7 0.0 0.00042 20.3 0.0 3.4 3 0 0 3 3 3 1 Transposase HTH_38 PF13936.1 EMG45211.1 - 0.00044 19.7 0.0 0.003 17.0 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.1 EMG45211.1 - 0.00046 20.3 0.0 0.0012 18.9 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EMG45211.1 - 0.0027 18.4 0.1 0.013 16.3 0.1 2.2 2 0 0 2 2 2 1 Homeodomain-like domain Trypan_PARP PF05887.6 EMG45211.1 - 0.058 13.2 16.0 0.22 11.3 11.1 2.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HTH_24 PF13412.1 EMG45211.1 - 0.12 11.8 0.2 1.9 7.9 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding SSF PF00474.12 EMG45212.1 - 2e-23 82.7 27.9 3.3e-23 81.9 19.3 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family WTF PF03303.8 EMG45212.1 - 0.0042 16.5 1.2 0.028 13.8 0.0 2.4 2 0 0 2 2 2 1 WTF protein Catalase PF00199.14 EMG45214.1 - 1.2e-99 333.5 0.9 1.9e-99 332.9 0.6 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EMG45214.1 - 1.7e-14 53.4 0.1 1.7e-13 50.1 0.1 2.3 2 0 0 2 2 2 1 Catalase-related immune-responsive Sugar_tr PF00083.19 EMG45215.1 - 1e-62 212.2 7.2 1.2e-62 212.0 5.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG45215.1 - 7.9e-11 41.2 3.3 7.9e-11 41.2 2.3 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily UPF0233 PF06781.7 EMG45215.1 - 0.043 13.4 0.1 4.1 7.0 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) Hyphal_reg_CWP PF11765.3 EMG45216.1 - 2.1e-92 309.4 7.9 2.5e-92 309.1 5.5 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Ig_2 PF13895.1 EMG45216.1 - 0.023 14.8 0.3 0.14 12.2 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin domain DIPSY PF11763.3 EMG45216.1 - 0.29 10.9 2.8 0.35 10.6 0.6 2.0 2 1 0 2 2 2 0 Cell-wall adhesin ligand-binding C-terminal GTP_EFTU PF00009.22 EMG45219.1 - 6.4e-62 208.3 0.7 8.6e-62 207.9 0.5 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EMG45219.1 - 1.3e-22 79.7 0.0 4e-22 78.2 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EMG45219.1 - 1.9e-21 75.9 1.5 1.9e-21 75.9 1.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EMG45219.1 - 4.2e-06 26.3 0.3 9.8e-06 25.1 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EMG45219.1 - 3.6e-05 23.7 0.0 6.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMG45219.1 - 0.0034 17.8 0.0 0.0063 17.0 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EMG45219.1 - 0.0073 15.8 0.1 3.9 6.9 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation DisA_N PF02457.11 EMG45219.1 - 0.1 11.7 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding cobW PF02492.14 EMG45219.1 - 0.1 12.0 0.5 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pex16 PF08610.5 EMG45220.1 - 0.3 10.0 4.5 0.49 9.3 3.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Shadoo PF14999.1 EMG45220.1 - 0.35 10.7 11.0 0.59 9.9 7.7 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Pex14_N PF04695.8 EMG45220.1 - 6.2 6.8 10.9 0.66 10.0 3.7 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hyphal_reg_CWP PF11765.3 EMG45221.1 - 6.7e-86 288.0 13.1 7.6e-86 287.8 9.1 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal DUF4176 PF13780.1 EMG45221.1 - 0.096 12.4 0.0 0.34 10.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4176) Hyphal_reg_CWP PF11765.3 EMG45222.1 - 2.4e-149 496.6 20.0 2.9e-149 496.3 13.8 1.1 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal DUF995 PF06191.7 EMG45222.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF995) Flocculin_t3 PF13928.1 EMG45223.1 - 0.015 15.3 20.2 0.015 15.3 14.0 9.4 3 3 2 5 5 5 0 Flocculin type 3 repeat Sugar_tr PF00083.19 EMG45225.1 - 3.1e-51 174.3 13.7 3.5e-51 174.1 9.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter TM_helix PF05552.7 EMG45225.1 - 0.068 12.8 0.2 0.25 11.0 0.2 2.0 1 0 0 1 1 1 0 Conserved TM helix Pput2613-deam PF14427.1 EMG45226.1 - 0.00019 21.0 32.4 0.36 10.5 0.4 7.4 1 1 7 8 8 8 7 Pput_2613-like deaminase D-aminoacyl_C PF07908.7 EMG45226.1 - 8.2 5.8 10.9 36 3.7 0.1 4.6 5 0 0 5 5 5 0 D-aminoacylase, C-terminal region Aconitase PF00330.15 EMG45227.1 - 1.8e-123 412.5 0.0 2e-123 412.3 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Amidase PF01425.16 EMG45228.1 - 1.3e-16 60.5 0.0 1.5e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Amidase Candida_ALS PF05792.8 EMG45229.1 - 9.6e-27 92.8 26.2 1.6e-08 34.4 0.9 5.1 5 0 0 5 5 5 4 Candida agglutinin-like (ALS) HNH_3 PF13392.1 EMG45229.1 - 4.4e-06 25.9 6.5 0.19 11.1 0.1 4.1 4 0 0 4 4 4 2 HNH endonuclease OB_RNB PF08206.6 EMG45229.1 - 0.018 14.5 2.2 6.8 6.2 0.0 4.1 4 1 0 4 4 4 0 Ribonuclease B OB domain Candida_ALS PF05792.8 EMG45230.1 - 1.3e-14 53.9 7.8 1.7e-05 24.7 0.3 3.7 3 0 0 3 3 3 3 Candida agglutinin-like (ALS) HNH_3 PF13392.1 EMG45230.1 - 0.0003 20.1 7.8 0.077 12.4 0.1 3.2 3 0 0 3 3 3 2 HNH endonuclease OB_RNB PF08206.6 EMG45230.1 - 0.089 12.3 0.5 7.4 6.1 0.0 3.3 3 0 0 3 3 3 0 Ribonuclease B OB domain DDE_3 PF13358.1 EMG45231.1 - 3.8e-09 36.4 0.2 1.7e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Rabaptin PF03528.10 EMG45231.1 - 0.059 13.2 0.3 0.1 12.5 0.2 1.5 1 0 0 1 1 1 0 Rabaptin Carot_N PF09150.5 EMG45231.1 - 0.06 13.0 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal Creatinase_N PF01321.13 EMG45232.1 - 0.06 13.8 0.3 0.087 13.3 0.2 1.3 1 0 0 1 1 1 0 Creatinase/Prolidase N-terminal domain TOBE_2 PF08402.5 EMG45232.1 - 0.27 11.2 3.7 8.3 6.4 1.1 2.2 1 1 1 2 2 2 0 TOBE domain DUF1644 PF07800.7 EMG45234.1 - 0.00025 20.9 0.6 0.00032 20.6 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1644) zf-H2C2_5 PF13909.1 EMG45234.1 - 0.0055 16.8 0.2 0.0055 16.8 0.1 2.4 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.10 EMG45234.1 - 0.083 12.4 0.2 0.23 11.0 0.1 1.7 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Sina PF03145.11 EMG45234.1 - 0.17 11.4 4.2 0.32 10.6 2.6 1.7 1 1 0 1 1 1 0 Seven in absentia protein family DUF3439 PF11921.3 EMG45235.1 - 0.0084 15.8 4.2 0.0098 15.6 2.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) MFS_1 PF07690.11 EMG45236.1 - 0.00075 18.3 12.3 0.00087 18.1 8.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG45236.1 - 0.0062 15.1 11.0 0.0066 15.0 7.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DDE_1 PF03184.14 EMG45237.1 - 2.4e-09 36.6 0.0 5.9e-09 35.3 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EMG45237.1 - 1.4e-05 24.8 0.2 3.7e-05 23.4 0.2 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3844 PF12955.2 EMG45238.1 - 4.1e-07 30.0 10.1 6.5e-07 29.4 7.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF PF00008.22 EMG45238.1 - 0.0015 18.4 2.4 0.0026 17.7 1.6 1.3 1 0 0 1 1 1 1 EGF-like domain DUF1043 PF06295.7 EMG45238.1 - 0.014 15.0 1.8 0.52 9.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) EGF_CA PF07645.10 EMG45238.1 - 0.082 12.9 7.7 0.14 12.1 5.4 1.3 1 0 0 1 1 1 0 Calcium-binding EGF domain EGF_3 PF12947.2 EMG45238.1 - 0.13 12.2 7.8 0.22 11.5 5.4 1.3 1 0 0 1 1 1 0 EGF domain ABC2_membrane PF01061.19 EMG45239.1 - 4.9e-06 25.8 2.1 6.5e-06 25.4 1.5 1.1 1 0 0 1 1 1 1 ABC-2 type transporter Candida_ALS PF05792.8 EMG45240.1 - 6.5e-16 58.1 97.4 8.2e-06 25.8 9.4 5.1 5 0 0 5 5 5 4 Candida agglutinin-like (ALS) Nucleoporin_FG PF13634.1 EMG45240.1 - 0.004 17.3 16.2 0.076 13.2 11.2 2.2 1 1 0 1 1 1 1 Nucleoporin FG repeat region Orthoreo_P10 PF07204.6 EMG45240.1 - 0.14 11.9 2.6 14 5.4 0.0 3.0 1 1 3 4 4 4 0 Orthoreovirus membrane fusion protein p10 ABC_tran PF00005.22 EMG45241.1 - 1.5e-13 51.1 0.0 2e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EMG45241.1 - 2.8e-05 23.3 0.0 3.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EMG45241.1 - 3.3e-05 23.3 0.1 4.4e-05 22.9 0.0 1.3 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 EMG45241.1 - 8.6e-05 22.0 0.2 0.00016 21.2 0.1 1.5 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EMG45241.1 - 0.00044 21.0 0.0 0.00077 20.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMG45241.1 - 0.0013 19.0 0.1 0.0022 18.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMG45241.1 - 0.0022 18.0 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EMG45241.1 - 0.0027 17.1 0.6 0.0075 15.7 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EMG45241.1 - 0.0045 17.1 0.0 0.006 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EMG45241.1 - 0.0053 16.3 0.2 0.0089 15.6 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EMG45241.1 - 0.012 15.2 0.1 0.019 14.6 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_21 PF13304.1 EMG45241.1 - 0.016 15.2 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EMG45241.1 - 0.017 15.0 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.4 EMG45241.1 - 0.018 13.6 0.1 0.028 13.0 0.1 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class RNA_helicase PF00910.17 EMG45241.1 - 0.022 14.9 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.18 EMG45241.1 - 0.033 14.1 0.1 0.058 13.3 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.1 EMG45241.1 - 0.033 14.5 0.5 0.055 13.7 0.4 1.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMG45241.1 - 0.038 13.7 0.0 0.061 13.0 0.0 1.4 1 1 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 EMG45241.1 - 0.063 13.2 0.1 0.082 12.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EMG45241.1 - 0.079 12.4 0.1 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 EMG45241.1 - 0.099 12.2 0.1 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EMG45241.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Herpes_Helicase PF02689.9 EMG45241.1 - 0.11 10.1 0.0 0.12 10.0 0.0 1.1 1 0 0 1 1 1 0 Helicase NMT1 PF09084.6 EMG45242.1 - 1.8e-29 102.8 0.0 2.5e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EMG45242.1 - 0.0038 16.6 0.1 0.013 14.9 0.1 1.7 1 1 0 1 1 1 1 NMT1-like family Peptidase_M24 PF00557.19 EMG45243.1 - 2.1e-11 43.7 0.0 2.4e-11 43.6 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 NADHdh_A3 PF14987.1 EMG45245.1 - 0.00012 21.9 0.6 0.00052 19.8 0.2 2.0 2 0 0 2 2 2 1 NADH dehydrogenase 1 alpha subcomplex subunit 3 DUF2057 PF09829.4 EMG45246.1 - 0.18 11.4 3.9 0.23 11.1 2.7 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) DSRB PF10781.4 EMG45247.1 - 1.2e-05 24.7 0.1 6.3 6.3 0.0 4.0 4 0 0 4 4 4 3 Dextransucrase DSRB Imm33 PF15580.1 EMG45247.1 - 0.0037 16.7 0.8 17 5.0 0.0 3.1 3 0 0 3 3 3 3 Immunity protein 33 DsbC_N PF10411.4 EMG45247.1 - 0.17 11.1 6.1 8.2 5.7 0.1 4.0 4 0 0 4 4 4 0 Disulfide bond isomerase protein N-terminus DUF35 PF01796.12 EMG45247.1 - 0.99 9.6 12.0 4.1 7.7 0.2 3.9 2 2 2 4 4 4 0 DUF35 OB-fold domain NMT1 PF09084.6 EMG45248.1 - 4e-31 108.2 0.0 4.5e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EMG45248.1 - 0.0016 17.8 0.0 0.0017 17.8 0.0 1.1 1 0 0 1 1 1 1 NMT1-like family Pput2613-deam PF14427.1 EMG45249.1 - 0.047 13.3 6.3 1.4 8.6 0.2 3.6 1 1 3 4 4 4 0 Pput_2613-like deaminase DUF3254 PF11630.3 EMG45249.1 - 0.076 12.9 8.2 11 6.0 0.1 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF3254) Cas_Cmr3 PF09700.5 EMG45249.1 - 1.4 8.2 4.5 26 4.0 0.1 3.0 1 1 1 3 3 3 0 CRISPR-associated protein (Cas_Cmr3) Aconitase PF00330.15 EMG45250.1 - 1.1e-53 182.4 0.2 1.2e-53 182.2 0.1 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) MDM31_MDM32 PF08118.6 EMG45252.1 - 1.4e-12 46.8 0.3 1.7e-12 46.5 0.2 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Hyphal_reg_CWP PF11765.3 EMG45253.1 - 0.0031 16.3 0.1 0.006 15.3 0.1 1.5 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal DUF3875 PF12991.2 EMG45253.1 - 0.14 11.9 0.3 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3875) DUF4124 PF13511.1 EMG45253.1 - 0.29 11.2 3.9 11 6.1 0.4 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4124) Qn_am_d_aII PF14930.1 EMG45253.1 - 0.47 10.4 3.4 50 3.9 0.1 3.4 1 1 3 4 4 4 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II Pput2613-deam PF14427.1 EMG45253.1 - 0.69 9.6 7.9 1.6 8.4 0.4 3.1 2 1 2 4 4 4 0 Pput_2613-like deaminase DUF4425 PF14466.1 EMG45253.1 - 8.9 6.4 15.4 11 6.2 3.7 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4425) Hyphal_reg_CWP PF11765.3 EMG45254.1 - 2.5e-42 144.8 0.1 2.6e-42 144.7 0.1 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal MFS_1 PF07690.11 EMG45255.1 - 6.9e-10 38.1 4.8 8.2e-10 37.9 3.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily FAD_binding_3 PF01494.14 EMG45256.1 - 1.4e-13 50.6 0.0 1.7e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EMG45257.1 - 7.2e-13 48.3 0.0 8.8e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SSF PF00474.12 EMG45259.1 - 8.4e-09 34.5 0.8 9e-09 34.4 0.5 1.0 1 0 0 1 1 1 1 Sodium:solute symporter family Candida_ALS PF05792.8 EMG45261.1 - 4e-20 71.6 98.1 8e-10 38.6 7.4 5.1 5 0 0 5 5 5 4 Candida agglutinin-like (ALS) Nucleoporin_FG PF13634.1 EMG45261.1 - 3 8.1 12.1 5.8 7.1 8.4 1.8 1 1 0 1 1 1 0 Nucleoporin FG repeat region Imm33 PF15580.1 EMG45263.1 - 0.052 13.0 0.2 32 4.0 0.0 2.9 2 1 0 2 2 2 0 Immunity protein 33 PPV_E2_C PF00511.12 EMG45263.1 - 3.8 7.5 13.6 7.8 6.5 0.6 3.2 3 0 0 3 3 3 0 E2 (early) protein, C terminal Hyphal_reg_CWP PF11765.3 EMG45264.1 - 1.5e-39 135.7 3.4 1.8e-39 135.4 2.4 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Pput2613-deam PF14427.1 EMG45265.1 - 0.016 14.9 8.5 5.1 6.7 0.2 3.9 1 1 3 4 4 4 0 Pput_2613-like deaminase Chitin_bind_4 PF00379.18 EMG45265.1 - 0.68 10.2 8.2 7.2 6.9 0.1 3.5 3 0 0 3 3 3 0 Insect cuticle protein DUF4232 PF14016.1 EMG45265.1 - 5 6.7 10.2 4.5 6.9 3.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4232) PPV_E2_C PF00511.12 EMG45265.1 - 9.5 6.2 14.1 2.7 8.0 1.1 3.4 1 1 2 3 3 3 0 E2 (early) protein, C terminal Pput2613-deam PF14427.1 EMG45266.1 - 2.2e-05 24.1 6.1 0.31 10.7 0.1 3.1 1 1 2 3 3 3 3 Pput_2613-like deaminase DUF4028 PF13220.1 EMG45266.1 - 0.037 13.6 0.1 3.5 7.3 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4028) MMPL PF03176.10 EMG45266.1 - 0.14 10.8 5.6 6.4 5.3 0.2 2.9 1 1 1 3 3 3 0 MMPL family Chitin_bind_4 PF00379.18 EMG45266.1 - 0.15 12.3 19.0 3.2 8.0 0.9 4.4 4 0 0 4 4 4 0 Insect cuticle protein DUF3254 PF11630.3 EMG45266.1 - 0.78 9.7 5.2 11 6.0 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3254) CENP-T PF15511.1 EMG45266.1 - 0.84 8.8 6.7 0.93 8.6 4.6 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Herpes_LMP1 PF05297.6 EMG45266.1 - 5.7 5.7 13.4 6.8 5.5 9.3 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) PDR_CDR PF06422.7 EMG45267.1 - 1.5e-24 85.5 0.0 2.9e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 CDR ABC transporter ABC2_membrane PF01061.19 EMG45267.1 - 8.1e-15 54.5 5.4 8.1e-15 54.5 3.8 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 EMG45267.1 - 2.8e-05 23.3 4.1 6.2e-05 22.1 2.8 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein DUF1586 PF07625.6 EMG45267.1 - 0.051 13.3 1.8 0.088 12.5 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1586) Qn_am_d_aII PF14930.1 EMG45268.1 - 0.07 13.0 3.0 9 6.3 0.0 3.0 3 1 1 4 4 4 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II CopC PF04234.7 EMG45268.1 - 0.64 10.6 4.4 2.6 8.7 0.5 2.5 1 1 1 2 2 2 0 CopC domain HDPD PF02924.9 EMG45268.1 - 5.7 6.7 13.3 0.33 10.7 1.8 2.7 2 1 0 2 2 2 0 Bacteriophage lambda head decoration protein D Flocculin_t3 PF13928.1 EMG45269.1 - 2.2e-08 34.1 34.9 2.2e-08 34.1 24.2 3.8 2 1 1 3 3 3 1 Flocculin type 3 repeat Ribosomal_S4e PF00900.15 EMG45270.1 - 2e-23 81.8 0.2 5.6e-23 80.4 0.1 1.8 2 0 0 2 2 2 1 Ribosomal family S4e KOW PF00467.24 EMG45270.1 - 4.7e-06 26.1 2.7 4.7e-06 26.1 1.9 3.1 3 0 0 3 3 3 1 KOW motif DAO PF01266.19 EMG45271.1 - 5.6e-11 41.9 1.8 1.3e-06 27.6 1.3 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EMG45271.1 - 1.4e-10 40.7 0.0 1.6e-10 40.6 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EMG45271.1 - 1.1e-08 35.3 0.7 8.4e-06 26.0 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMG45271.1 - 1.4e-08 34.2 0.9 3.6e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 EMG45271.1 - 2.1e-08 33.6 0.0 2.8e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMG45271.1 - 4.5e-08 32.9 0.3 8.9e-08 32.0 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMG45271.1 - 5.6e-08 32.0 0.7 0.0041 16.1 0.4 2.0 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.19 EMG45271.1 - 1.1e-07 31.0 1.9 2.1e-07 30.1 1.3 1.5 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 EMG45271.1 - 2.7e-07 29.5 1.7 0.0012 17.5 0.4 2.0 1 1 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.9 EMG45271.1 - 5.3e-07 28.4 1.4 1.1e-05 24.0 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EMG45271.1 - 3e-05 23.9 2.3 9.3e-05 22.3 1.6 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMG45271.1 - 0.00021 20.4 0.8 0.00049 19.2 0.1 1.8 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 EMG45271.1 - 0.00059 18.8 3.3 0.0038 16.1 0.7 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EMG45271.1 - 0.00066 19.8 0.2 0.0014 18.7 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EMG45271.1 - 0.001 19.0 0.1 0.028 14.4 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 EMG45271.1 - 0.012 14.9 0.3 0.012 14.9 0.2 1.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.1 EMG45271.1 - 0.015 15.3 0.2 0.033 14.2 0.1 1.6 2 0 0 2 2 2 0 NADH(P)-binding NAD_binding_9 PF13454.1 EMG45271.1 - 0.076 12.7 2.1 5.4 6.7 0.4 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pput2613-deam PF14427.1 EMG45277.1 - 0.023 14.3 0.4 0.12 12.0 0.0 2.0 1 1 1 2 2 2 0 Pput_2613-like deaminase Rap1_C PF11626.3 EMG45277.1 - 0.67 9.8 0.0 0.67 9.8 0.0 2.2 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Big_1 PF02369.11 EMG45279.1 - 0.017 15.0 6.4 0.83 9.5 1.0 2.2 1 1 1 2 2 2 0 Bacterial Ig-like domain (group 1) Pput2613-deam PF14427.1 EMG45279.1 - 0.073 12.7 0.4 0.57 9.8 0.1 1.9 1 1 1 2 2 2 0 Pput_2613-like deaminase DUF3254 PF11630.3 EMG45279.1 - 0.26 11.2 2.0 3.6 7.6 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3254) CBM_5_12_2 PF14600.1 EMG45279.1 - 1.2 8.8 7.3 4.6 6.9 0.6 2.4 1 1 0 2 2 2 0 Cellulose-binding domain DLH PF01738.13 EMG45282.1 - 5.2e-11 42.2 0.0 6.3e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family CR6_interact PF10147.4 EMG45283.1 - 0.0041 16.4 11.7 0.0049 16.2 8.1 1.1 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 PilJ PF13675.1 EMG45283.1 - 0.012 15.8 2.0 0.025 14.8 1.4 1.5 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term YlqD PF11068.3 EMG45283.1 - 0.017 15.1 15.2 0.053 13.5 10.5 1.7 1 1 0 1 1 1 0 YlqD protein DUF2730 PF10805.3 EMG45283.1 - 0.019 14.7 4.1 0.019 14.7 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Hema_stalk PF08720.5 EMG45283.1 - 0.02 14.4 1.5 0.022 14.2 1.1 1.2 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk SlyX PF04102.7 EMG45283.1 - 0.021 15.1 8.6 0.46 10.8 0.4 3.2 1 1 2 3 3 3 0 SlyX Syntaxin PF00804.20 EMG45283.1 - 0.028 14.5 14.4 0.32 11.1 9.3 2.3 1 1 0 1 1 1 0 Syntaxin Uds1 PF15456.1 EMG45283.1 - 0.068 13.1 12.5 0.6 10.1 4.4 2.1 1 1 1 2 2 2 0 Up-regulated During Septation DUF2450 PF10475.4 EMG45283.1 - 0.081 11.8 6.2 0.093 11.6 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Poty_PP PF08440.5 EMG45283.1 - 0.11 11.5 8.9 0.56 9.2 6.2 1.8 1 1 0 1 1 1 0 Potyviridae polyprotein GLE1 PF07817.8 EMG45283.1 - 0.12 11.3 7.9 0.12 11.3 4.9 1.4 1 1 0 1 1 1 0 GLE1-like protein FlxA PF14282.1 EMG45283.1 - 0.12 12.3 19.8 1.6 8.6 5.1 2.5 1 1 1 2 2 2 0 FlxA-like protein Effector_1 PF04518.7 EMG45283.1 - 0.14 11.1 9.1 0.16 10.9 6.3 1.2 1 0 0 1 1 1 0 Effector from type III secretion system Kinesin-related PF06548.6 EMG45283.1 - 0.14 10.6 16.8 0.17 10.4 11.6 1.1 1 0 0 1 1 1 0 Kinesin-related PEP-utilisers_N PF05524.8 EMG45283.1 - 0.17 11.7 7.1 0.47 10.2 4.5 1.9 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Cytochrom_C_2 PF01322.15 EMG45283.1 - 0.21 12.1 3.5 0.32 11.5 2.5 1.4 1 1 0 1 1 1 0 Cytochrome C' FlaC_arch PF05377.6 EMG45283.1 - 0.22 11.4 9.1 0.18 11.7 1.0 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 EMG45283.1 - 0.22 11.8 14.3 0.51 10.7 9.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF4613 PF15390.1 EMG45283.1 - 0.23 9.5 11.0 0.28 9.3 7.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) OHCU_decarbox PF09349.5 EMG45283.1 - 0.24 11.6 3.5 0.33 11.2 2.4 1.2 1 0 0 1 1 1 0 OHCU decarboxylase COG5 PF10392.4 EMG45283.1 - 0.28 11.1 9.4 0.79 9.6 6.5 1.7 1 1 0 1 1 1 0 Golgi transport complex subunit 5 ImcF-related_N PF14331.1 EMG45283.1 - 0.3 9.9 3.3 0.41 9.5 2.0 1.4 1 1 1 2 2 2 0 ImcF-related N-terminal domain DivIC PF04977.10 EMG45283.1 - 0.41 10.1 17.6 0.2 11.1 3.9 3.1 1 1 2 3 3 3 0 Septum formation initiator DUF342 PF03961.8 EMG45283.1 - 0.43 8.9 17.0 0.47 8.8 11.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Gasdermin PF04598.7 EMG45283.1 - 0.5 9.0 8.6 0.54 8.9 6.0 1.0 1 0 0 1 1 1 0 Gasdermin family DUF4140 PF13600.1 EMG45283.1 - 0.54 10.7 11.4 6.3 7.2 1.2 2.5 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF1664 PF07889.7 EMG45283.1 - 0.67 9.7 11.1 0.91 9.3 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Mnd1 PF03962.10 EMG45283.1 - 0.69 9.5 18.7 0.96 9.0 5.3 2.0 1 1 1 2 2 2 0 Mnd1 family DUF3584 PF12128.3 EMG45283.1 - 0.75 7.0 15.1 1.2 6.3 10.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 EMG45283.1 - 0.85 8.2 18.1 1.1 7.8 12.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2408 PF10303.4 EMG45283.1 - 0.88 9.6 13.4 0.89 9.6 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Syntaxin_2 PF14523.1 EMG45283.1 - 0.91 9.5 15.1 27 4.8 3.0 2.0 1 1 0 1 1 1 0 Syntaxin-like protein ABC_tran_2 PF12848.2 EMG45283.1 - 1.1 9.1 15.8 0.87 9.4 6.8 2.1 1 1 1 2 2 2 0 ABC transporter AAA_13 PF13166.1 EMG45283.1 - 1.2 7.5 16.7 1.2 7.4 11.6 1.1 1 0 0 1 1 1 0 AAA domain CENP-H PF05837.7 EMG45283.1 - 1.2 9.3 17.4 0.66 10.1 3.7 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DASH_Dad3 PF08656.5 EMG45283.1 - 1.4 8.6 10.2 3.4 7.4 2.6 2.8 1 1 2 3 3 3 0 DASH complex subunit Dad3 DUF2252 PF10009.4 EMG45283.1 - 2.1 7.1 7.1 2.2 7.0 5.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) ACCA PF03255.9 EMG45283.1 - 2.4 7.7 12.7 0.38 10.3 1.7 2.1 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF1192 PF06698.6 EMG45283.1 - 3 7.7 7.9 2.4 8.0 0.1 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1192) FUSC-like PF12805.2 EMG45283.1 - 3.3 6.5 4.8 3.9 6.3 3.3 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DUF3450 PF11932.3 EMG45283.1 - 3.3 6.8 11.6 1.8 7.7 3.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) SidE PF12252.3 EMG45283.1 - 3.7 4.7 14.0 4.6 4.4 9.7 1.0 1 0 0 1 1 1 0 Dot/Icm substrate protein Fib_alpha PF08702.5 EMG45283.1 - 3.7 7.6 13.9 8.9 6.4 5.1 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CCDC-167 PF15188.1 EMG45283.1 - 3.8 7.5 18.4 3.2 7.7 2.3 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 bZIP_1 PF00170.16 EMG45283.1 - 3.9 7.5 19.4 4.4 7.3 3.0 3.1 1 1 2 3 3 3 0 bZIP transcription factor Val_tRNA-synt_C PF10458.4 EMG45283.1 - 4.4 7.4 17.2 1.8 8.6 0.6 3.1 1 1 1 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DUF2175 PF09943.4 EMG45283.1 - 4.6 7.3 10.7 9.3 6.3 7.1 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Dabb PF07876.7 EMG45283.1 - 4.8 7.6 5.9 16 6.0 0.5 2.6 1 1 2 3 3 3 0 Stress responsive A/B Barrel Domain YvrJ PF12841.2 EMG45283.1 - 5.2 6.4 5.6 2.4 7.5 0.2 2.7 3 0 0 3 3 3 0 YvrJ protein family Remorin_C PF03763.8 EMG45283.1 - 5.9 6.4 16.4 11 5.6 9.9 2.0 1 1 1 2 2 2 0 Remorin, C-terminal region LUC7 PF03194.10 EMG45283.1 - 6.1 6.3 14.3 7 6.0 9.9 1.2 1 0 0 1 1 1 0 LUC7 N_terminus DUF2743 PF10899.3 EMG45283.1 - 6.1 6.1 9.2 14 5.0 5.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2743) IncA PF04156.9 EMG45283.1 - 8.4 5.9 15.3 25 4.4 10.6 1.7 1 1 0 1 1 1 0 IncA protein AA_permease PF00324.16 EMG45284.1 - 3e-10 39.0 8.5 3.4e-10 38.8 5.9 1.0 1 0 0 1 1 1 1 Amino acid permease Na_Ala_symp PF01235.12 EMG45284.1 - 0.0034 16.0 0.3 0.0035 15.9 0.2 1.1 1 0 0 1 1 1 1 Sodium:alanine symporter family SSF PF00474.12 EMG45284.1 - 0.031 12.9 1.3 0.035 12.7 0.9 1.1 1 0 0 1 1 1 0 Sodium:solute symporter family ETRAMP PF09716.5 EMG45284.1 - 0.039 13.8 0.2 0.06 13.3 0.1 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) AA_permease_2 PF13520.1 EMG45284.1 - 0.24 9.9 5.7 0.27 9.7 3.9 1.0 1 0 0 1 1 1 0 Amino acid permease Sulf_transp PF04143.9 EMG45284.1 - 0.95 9.5 11.1 1.4 8.9 7.7 1.4 1 1 0 1 1 1 0 Sulphur transport SRP9-21 PF05486.7 EMG45285.1 - 0.00029 20.5 0.3 4.3 7.1 0.0 3.0 1 1 2 3 3 3 2 Signal recognition particle 9 kDa protein (SRP9) E1_DerP2_DerF2 PF02221.10 EMG45285.1 - 0.0046 17.2 0.8 2.8 8.1 0.1 2.2 1 1 1 2 2 2 2 ML domain MAR_sialic_bdg PF10564.4 EMG45285.1 - 0.015 15.0 0.4 9.6 6.0 0.0 2.8 2 1 1 3 3 3 0 Sialic-acid binding micronemal adhesive repeat DUF464 PF04327.7 EMG45285.1 - 0.016 15.4 2.0 7.4 6.8 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF464) Polyketide_cyc2 PF10604.4 EMG45285.1 - 0.068 13.3 9.8 1.2 9.3 1.0 2.2 1 1 1 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport FctA PF12892.2 EMG45285.1 - 0.11 13.2 4.7 2.1 9.1 0.4 2.3 1 1 1 2 2 2 0 T surface-antigen of pili TF_Zn_Ribbon PF08271.7 EMG45285.1 - 0.13 11.5 3.5 6.5 6.1 0.1 3.0 3 0 0 3 3 3 0 TFIIB zinc-binding DUF4425 PF14466.1 EMG45285.1 - 0.15 12.1 8.6 2.8 8.0 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4425) Chitin_bind_4 PF00379.18 EMG45285.1 - 0.17 12.1 1.3 9.8 6.5 0.1 2.6 2 0 0 2 2 2 0 Insect cuticle protein VD10_N PF08476.5 EMG45285.1 - 0.71 9.3 6.8 36 3.9 0.1 3.3 3 0 0 3 3 3 0 Viral D10 N-terminal PPV_E2_C PF00511.12 EMG45285.1 - 4.1 7.4 6.6 16 5.4 0.3 2.4 2 0 0 2 2 2 0 E2 (early) protein, C terminal RE_AccI PF09545.5 EMG45286.1 - 0.12 10.8 0.3 0.14 10.7 0.2 1.0 1 0 0 1 1 1 0 AccI restriction endonuclease RE_AccI PF09545.5 EMG45287.1 - 0.12 10.8 0.3 0.14 10.7 0.2 1.0 1 0 0 1 1 1 0 AccI restriction endonuclease Pput2613-deam PF14427.1 EMG45288.1 - 8.8e-05 22.1 1.4 0.15 11.7 0.1 2.1 1 1 1 2 2 2 2 Pput_2613-like deaminase MMPL PF03176.10 EMG45288.1 - 0.29 9.8 1.2 1.8 7.1 0.2 1.9 1 1 1 2 2 2 0 MMPL family CBM_5_12_2 PF14600.1 EMG45288.1 - 2.1 8.0 7.7 13 5.5 0.3 3.1 3 0 0 3 3 3 0 Cellulose-binding domain DUF4425 PF14466.1 EMG45288.1 - 5 7.2 7.2 13 5.9 0.6 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4425) Chitin_bind_4 PF00379.18 EMG45288.1 - 8.3 6.7 12.7 1.9 8.8 0.8 3.2 3 0 0 3 3 3 0 Insect cuticle protein CT47 PF15623.1 EMG45289.1 - 0.73 9.5 20.9 0.86 9.2 14.5 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 DUF1675 PF07897.6 EMG45289.1 - 1.6 8.5 15.2 1.9 8.2 10.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Tir_receptor_C PF07489.6 EMG45289.1 - 1.9 8.1 20.6 2.5 7.8 14.3 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus DUF2052 PF09747.4 EMG45289.1 - 7.4 6.4 14.4 8.8 6.2 10.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Fungal_trans PF04082.13 EMG45290.1 - 2.6e-07 29.8 0.0 3e-07 29.5 0.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain PIG-H PF10181.4 EMG45290.1 - 0.44 10.2 1.8 3.3 7.4 0.1 2.8 2 2 2 4 4 4 0 GPI-GlcNAc transferase complex, PIG-H component Pput2613-deam PF14427.1 EMG45291.1 - 0.01 15.5 1.8 0.37 10.4 0.1 2.1 1 1 1 2 2 2 2 Pput_2613-like deaminase NADH_dehy_S2_C PF06444.6 EMG45291.1 - 0.082 13.2 1.6 0.082 13.2 1.1 2.5 4 0 0 4 4 4 0 NADH dehydrogenase subunit 2 C-terminus 7kD_DNA_binding PF02294.13 EMG45291.1 - 0.11 12.1 0.7 11 5.7 0.1 2.2 2 0 0 2 2 2 0 7kD DNA-binding domain Chitin_bind_4 PF00379.18 EMG45291.1 - 0.44 10.8 2.8 2 8.7 1.1 2.4 1 1 1 2 2 2 0 Insect cuticle protein DUF4425 PF14466.1 EMG45291.1 - 0.96 9.5 7.0 5.5 7.1 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4425) Imm33 PF15580.1 EMG45292.1 - 0.21 11.0 0.9 1.6 8.2 0.2 2.0 1 1 1 2 2 2 0 Immunity protein 33 AlaDh_PNT_C PF01262.16 EMG45292.1 - 2.4 7.6 7.9 2.8 7.4 0.6 2.1 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAM47 PF14642.1 EMG45294.1 - 0.21 10.8 1.1 0.35 10.1 0.6 1.3 1 1 0 1 1 1 0 FAM47 family DUF1935 PF09149.5 EMG45294.1 - 4.6 7.2 6.9 8.3 6.4 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1935) DUF1292 PF06949.6 EMG45295.1 - 0.05 13.9 0.0 0.07 13.4 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1292) DUF2398 PF09661.5 EMG45296.1 - 0.15 10.7 0.0 3.1 6.4 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2398) Pput2613-deam PF14427.1 EMG45296.1 - 0.18 11.4 1.6 4.4 7.0 0.2 2.2 1 1 1 2 2 2 0 Pput_2613-like deaminase SBBP PF06739.6 EMG45296.1 - 0.38 10.5 11.2 7.2 6.4 0.6 3.8 3 1 1 4 4 4 0 Beta-propeller repeat DUF4425 PF14466.1 EMG45296.1 - 2.1 8.5 6.3 8.3 6.5 0.2 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4425) 2-Hacid_dh_C PF02826.14 EMG45297.1 - 3.1e-12 45.9 0.0 3.4e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EMG45298.1 - 3.1e-12 45.9 0.0 3.4e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4376 PF14301.1 EMG45299.1 - 0.1 12.7 0.2 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) SRP9-21 PF05486.7 EMG45300.1 - 0.011 15.4 0.2 0.24 11.1 0.1 2.0 1 1 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) Polyketide_cyc2 PF10604.4 EMG45300.1 - 0.045 13.9 1.3 0.059 13.5 0.9 1.3 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport NPCBM_assoc PF10633.4 EMG45300.1 - 0.33 11.0 5.7 5.4 7.1 0.4 2.8 2 1 1 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase VD10_N PF08476.5 EMG45300.1 - 0.4 10.2 1.9 20 4.7 0.1 2.2 2 0 0 2 2 2 0 Viral D10 N-terminal DUF4596 PF15363.1 EMG45300.1 - 2.6 8.0 10.4 6.2 6.8 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4596) SHS2_Rpb7-N PF03876.12 EMG45304.1 - 1e-13 51.2 0.0 1.9e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 CorA PF01544.13 EMG45305.1 - 2.2e-11 43.3 2.8 3.5e-11 42.6 1.9 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein LsmAD PF06741.8 EMG45307.1 - 4.5e-30 103.5 3.1 4.5e-30 103.5 2.2 2.1 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 EMG45307.1 - 4.9e-13 48.8 0.0 1.7e-12 47.1 0.0 2.0 1 0 0 1 1 1 1 Ataxin 2 SM domain PAM2 PF07145.10 EMG45307.1 - 0.014 14.8 0.5 0.065 12.7 0.4 2.3 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Sec6 PF06046.8 EMG45308.1 - 4.4e-170 566.5 9.3 4.4e-170 566.5 6.4 1.5 2 0 0 2 2 2 1 Exocyst complex component Sec6 Ribosomal_S24e PF01282.14 EMG45309.1 - 9.1e-35 118.3 0.0 1.3e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S24e RAMPs PF03787.10 EMG45309.1 - 0.091 12.5 0.3 3 7.6 0.0 2.2 2 0 0 2 2 2 0 RAMP superfamily SeleniumBinding PF11524.3 EMG45309.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Selenium binding protein ADH_zinc_N PF00107.21 EMG45311.1 - 1e-07 31.5 0.0 1.7e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMG45311.1 - 0.00013 21.7 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EMG45311.1 - 0.0096 16.8 0.0 0.021 15.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HisG_C PF08029.6 EMG45311.1 - 0.062 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 HisG, C-terminal domain Amidohydro_1 PF01979.15 EMG45312.1 - 2.5e-31 109.5 1.7 2.6e-17 63.5 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EMG45312.1 - 6.5e-25 88.6 0.0 2.2e-12 47.5 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EMG45312.1 - 3.8e-09 36.2 0.0 9.1e-09 35.0 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMG45312.1 - 1e-08 34.8 0.0 5e-05 22.7 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family DUF2347 PF09804.4 EMG45313.1 - 9.9e-73 244.8 3.8 1.5e-70 237.7 2.6 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 EMG45313.1 - 2.4e-31 109.1 9.1 4e-29 101.9 6.3 3.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4484) Mpv17_PMP22 PF04117.7 EMG45314.1 - 6.2e-08 32.1 1.2 6.2e-08 32.1 0.8 2.5 2 1 1 3 3 3 1 Mpv17 / PMP22 family ArfGap PF01412.13 EMG45316.1 - 5.8e-35 119.5 0.5 5.8e-35 119.5 0.4 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Tim44 PF04280.10 EMG45318.1 - 1e-33 116.3 0.1 2.7e-33 115.0 0.1 1.7 1 0 0 1 1 1 1 Tim44-like domain HAD_2 PF13419.1 EMG45319.1 - 2e-14 54.1 0.0 2.8e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMG45319.1 - 1.8e-09 38.3 0.0 2.5e-07 31.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMG45319.1 - 0.00048 19.7 0.2 0.00086 18.9 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EMG45319.1 - 0.057 13.5 0.0 0.089 12.9 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EMG45319.1 - 0.12 12.2 0.0 1.3 8.9 0.0 2.3 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Ribonucleas_3_3 PF14622.1 EMG45320.1 - 0.00076 19.4 0.0 0.0023 17.8 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EMG45320.1 - 0.0091 16.4 0.0 0.044 14.2 0.0 2.2 1 0 0 1 1 1 1 Ribonuclease III domain HALZ PF02183.13 EMG45320.1 - 0.1 12.3 0.3 13 5.5 0.0 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper AAA PF00004.24 EMG45321.1 - 3.3e-40 137.3 0.0 5.8e-40 136.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMG45321.1 - 4.4e-07 30.0 0.2 0.0019 18.3 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.9 EMG45321.1 - 8.7e-06 25.7 0.0 3.2e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EMG45321.1 - 2e-05 23.6 0.0 3.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EMG45321.1 - 9.7e-05 22.1 0.1 0.00045 19.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMG45321.1 - 0.00012 22.0 0.1 0.00077 19.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EMG45321.1 - 0.00068 19.5 0.1 0.0053 16.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EMG45321.1 - 0.00069 19.6 0.5 0.0028 17.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EMG45321.1 - 0.00076 18.5 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EMG45321.1 - 0.0044 17.8 1.0 0.012 16.4 0.2 2.3 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EMG45321.1 - 0.007 15.8 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EMG45321.1 - 0.0071 16.0 0.3 0.015 15.0 0.2 1.4 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 EMG45321.1 - 0.0078 15.3 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EMG45321.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMG45321.1 - 0.011 15.9 0.1 0.043 14.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EMG45321.1 - 0.012 15.2 0.0 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EMG45321.1 - 0.015 14.1 0.0 0.044 12.6 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 EMG45321.1 - 0.018 14.1 0.1 0.4 9.7 0.1 2.2 1 1 1 2 2 2 0 KaiC TIP49 PF06068.8 EMG45321.1 - 0.018 13.7 0.2 0.049 12.3 0.1 1.6 1 1 0 1 1 1 0 TIP49 C-terminus NTPase_1 PF03266.10 EMG45321.1 - 0.024 14.3 0.1 0.2 11.3 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.1 EMG45321.1 - 0.025 14.0 1.0 0.18 11.1 0.3 2.2 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 EMG45321.1 - 0.034 13.7 0.1 0.33 10.5 0.0 2.2 1 1 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 EMG45321.1 - 0.036 14.2 0.0 0.083 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EMG45321.1 - 0.046 13.2 0.2 0.13 11.8 0.2 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EMG45321.1 - 0.049 12.7 0.1 0.099 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EMG45321.1 - 0.058 12.6 0.6 0.19 10.9 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.4 EMG45321.1 - 0.14 11.0 0.1 0.25 10.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Peptidase_C48 PF02902.14 EMG45322.1 - 4.2e-24 85.3 4.4 9.6e-24 84.2 3.1 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain YqfQ PF14181.1 EMG45322.1 - 0.00029 20.9 1.3 0.00029 20.9 0.9 3.5 4 0 0 4 4 4 1 YqfQ-like protein CitT PF12431.3 EMG45322.1 - 0.043 13.8 0.0 0.14 12.2 0.0 2.0 1 0 0 1 1 1 0 Transcriptional regulator TPR_MLP1_2 PF07926.7 EMG45323.1 - 0.14 11.8 16.4 0.22 11.2 10.5 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Enkurin PF13864.1 EMG45323.1 - 0.8 9.9 8.3 2.6 8.2 5.7 2.0 1 1 0 1 1 1 0 Calmodulin-binding Syntaxin-6_N PF09177.6 EMG45323.1 - 1.1 9.7 12.1 6.7 7.1 3.6 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Reo_sigmaC PF04582.7 EMG45323.1 - 5.1 6.1 9.0 16 4.5 6.2 1.8 1 1 0 1 1 1 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EMG45323.1 - 9.3 6.1 20.0 2.4 8.0 10.8 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FAD_binding_3 PF01494.14 EMG45324.1 - 2e-18 66.6 0.0 3.7e-18 65.6 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMG45324.1 - 6.7e-06 26.0 0.0 1.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMG45324.1 - 1e-05 25.8 0.0 0.00014 22.2 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMG45324.1 - 4.3e-05 22.5 0.0 8.3e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.5 EMG45324.1 - 8.7e-05 21.4 0.0 0.0093 14.8 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase 3HCDH_N PF02737.13 EMG45324.1 - 0.00012 21.7 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EMG45324.1 - 0.0023 17.3 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.9 EMG45324.1 - 0.0061 16.4 0.0 0.045 13.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMG45324.1 - 0.0083 15.0 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A ApbA PF02558.11 EMG45324.1 - 0.014 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EMG45324.1 - 0.024 13.7 0.0 0.046 12.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LRR_4 PF12799.2 EMG45325.1 - 4.2e-11 42.2 27.8 0.00032 20.2 3.0 8.1 7 2 1 8 8 8 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG45325.1 - 1.2e-09 37.7 18.4 3.6e-05 23.4 0.4 7.0 8 1 0 8 8 8 2 Leucine rich repeat LRR_1 PF00560.28 EMG45325.1 - 0.00048 19.7 25.5 1.2 9.3 0.4 9.2 8 2 0 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.1 EMG45325.1 - 0.0013 18.6 18.2 4.9 7.5 0.4 8.8 9 0 0 9 9 9 1 Leucine Rich repeat LRR_2 PF07723.8 EMG45325.1 - 0.29 11.6 4.2 4.2 8.0 0.1 4.2 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 EMG45325.1 - 0.49 10.8 19.4 69 4.3 0.5 9.2 10 1 1 11 11 11 0 Leucine rich repeat FNIP PF05725.7 EMG45325.1 - 1.8 8.5 12.2 21 5.1 0.2 6.1 6 1 0 6 6 6 0 FNIP Repeat PTS_2-RNA PF01885.11 EMG45326.1 - 5.9e-45 152.8 2.3 2.4e-38 131.2 0.4 2.3 1 1 1 2 2 2 2 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.12 EMG45326.1 - 0.015 15.0 0.1 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 La domain Utp8 PF10395.4 EMG45327.1 - 1.7e-208 694.2 26.9 1.9e-208 694.0 18.6 1.0 1 0 0 1 1 1 1 Utp8 family MOZ_SAS PF01853.13 EMG45328.1 - 3.1e-77 258.0 0.6 6.3e-77 257.0 0.4 1.5 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EMG45328.1 - 1.9e-22 78.7 0.6 3.9e-22 77.6 0.4 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF1059 PF06348.6 EMG45328.1 - 0.031 14.0 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) He_PIG_assoc PF10632.4 EMG45328.1 - 0.16 11.3 0.5 0.37 10.1 0.3 1.5 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase WD40 PF00400.27 EMG45329.1 - 2.8e-51 169.6 11.6 1.2e-08 34.4 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EMG45329.1 - 1.3e-05 24.1 3.9 0.33 9.6 0.2 4.7 1 1 3 4 4 4 2 Nup133 N terminal like BBS2_Mid PF14783.1 EMG45329.1 - 0.0004 20.1 0.0 1.3 8.8 0.0 3.2 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 EMG45329.1 - 0.0051 15.0 2.4 0.22 9.6 0.1 3.2 3 2 1 4 4 4 2 Nucleoporin Nup120/160 WD40 PF00400.27 EMG45331.1 - 1.7e-67 221.0 5.4 2.7e-13 49.2 0.3 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EMG45331.1 - 4.9e-05 21.6 3.7 0.00016 19.9 0.2 2.9 2 2 0 3 3 3 1 Nucleoporin Nup120/160 HOOK PF05622.7 EMG45331.1 - 0.02 12.7 1.2 0.026 12.3 0.8 1.1 1 0 0 1 1 1 0 HOOK protein TPR_2 PF07719.12 EMG45332.1 - 2.8e-06 26.8 2.7 0.58 10.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMG45332.1 - 7.7e-05 22.5 0.3 0.4 10.6 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMG45332.1 - 0.00015 21.3 1.7 0.0076 15.8 0.2 3.1 1 1 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EMG45332.1 - 0.00026 20.4 7.1 0.31 10.7 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat F-box-like PF12937.2 EMG45332.1 - 0.0016 18.1 0.1 0.004 16.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like TPR_7 PF13176.1 EMG45332.1 - 0.0089 15.7 0.3 0.055 13.2 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat LRR_4 PF12799.2 EMG45332.1 - 0.016 14.7 19.4 0.067 12.8 1.4 5.9 3 1 3 6 6 6 0 Leucine Rich repeats (2 copies) TPR_6 PF13174.1 EMG45332.1 - 0.07 13.6 2.1 0.23 12.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat F-box PF00646.28 EMG45332.1 - 0.072 12.7 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 F-box domain TPR_8 PF13181.1 EMG45332.1 - 0.22 11.3 8.6 11 6.0 0.2 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat LRR_6 PF13516.1 EMG45332.1 - 0.3 11.2 0.1 0.3 11.2 0.1 6.3 7 0 0 7 7 6 0 Leucine Rich repeat LRR_7 PF13504.1 EMG45332.1 - 4.7 7.8 10.2 1.1e+02 3.6 0.0 6.8 8 0 0 8 8 7 0 Leucine rich repeat U3_snoRNA_assoc PF08297.6 EMG45333.1 - 1.1e-21 76.8 9.7 1.1e-21 76.8 6.7 2.9 2 1 0 2 2 2 1 U3 snoRNA associated LMBR1 PF04791.11 EMG45333.1 - 1.4 7.4 7.4 1.5 7.3 5.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein MFS_1 PF07690.11 EMG45334.1 - 5.9e-32 110.7 30.2 5.9e-32 110.7 21.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG45334.1 - 8.4e-09 34.5 15.0 8.4e-09 34.5 10.4 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter E1-E2_ATPase PF00122.15 EMG45334.1 - 0.13 11.2 2.0 0.31 10.0 1.4 1.6 1 0 0 1 1 1 0 E1-E2 ATPase AhpC-TSA PF00578.16 EMG45335.1 - 9.6e-23 80.2 0.0 1.4e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EMG45335.1 - 8e-18 64.3 0.0 1.1e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EMG45335.1 - 0.0027 17.6 0.0 0.0037 17.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme HSP70 PF00012.15 EMG45335.1 - 9.4 4.0 15.0 12 3.6 10.4 1.1 1 0 0 1 1 1 0 Hsp70 protein Pkinase PF00069.20 EMG45336.1 - 7.8e-57 192.3 6.3 5.7e-53 179.7 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMG45336.1 - 2.8e-18 65.9 0.0 6.7e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMG45336.1 - 0.024 14.3 0.2 0.073 12.7 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EMG45336.1 - 0.032 13.2 0.0 0.065 12.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like EAP30 PF04157.11 EMG45336.1 - 1.5 7.8 12.3 2.4 7.2 7.1 2.2 2 0 0 2 2 2 0 EAP30/Vps36 family Ist1 PF03398.9 EMG45337.1 - 1.2e-60 203.6 3.5 1.5e-60 203.3 2.5 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF3336 PF11815.3 EMG45338.1 - 2.1e-41 140.8 5.5 2.1e-41 140.8 3.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EMG45338.1 - 2.5e-29 102.6 0.0 6.5e-29 101.3 0.0 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase Lactamase_B_2 PF12706.2 EMG45339.1 - 5.2e-33 114.2 0.7 8.3e-33 113.5 0.5 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EMG45339.1 - 2.6e-17 62.0 0.2 7.5e-17 60.5 0.0 1.9 2 0 0 2 2 2 1 tRNase Z endonuclease Ribosomal_L2_C PF03947.13 EMG45341.1 - 3.4e-47 159.4 0.8 5.8e-47 158.7 0.6 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EMG45341.1 - 1.3e-25 89.1 0.6 2.3e-24 85.1 0.3 2.8 3 0 0 3 3 3 1 Ribosomal Proteins L2, RNA binding domain OSCP PF00213.13 EMG45342.1 - 6.9e-44 149.7 0.8 8e-44 149.5 0.5 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF3549 PF12069.3 EMG45342.1 - 0.0045 15.8 0.0 0.0059 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3549) Toxin_52 PF15605.1 EMG45342.1 - 0.011 15.5 0.1 0.035 13.9 0.1 1.8 2 0 0 2 2 2 0 Putative toxin 52 Metallophos PF00149.23 EMG45343.1 - 1.6e-16 60.2 11.2 4.6e-16 58.8 7.8 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase AA_permease PF00324.16 EMG45344.1 - 1.5e-78 264.2 16.2 1.8e-78 264.0 11.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG45344.1 - 3.4e-19 68.7 17.1 4.1e-19 68.4 11.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2892 PF11127.3 EMG45344.1 - 0.55 10.1 5.5 0.18 11.6 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) WD40 PF00400.27 EMG45345.1 - 2.4e-16 58.9 6.1 3.5e-06 26.6 0.2 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat PNP_UDP_1 PF01048.15 EMG45346.1 - 1.4e-35 122.3 0.0 1.6e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF919 PF06034.6 EMG45347.1 - 1.5 8.5 6.3 0.29 10.7 0.6 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DAGAT PF03982.8 EMG45348.1 - 5e-58 196.1 7.8 1.6e-27 95.9 0.0 5.1 4 1 0 4 4 4 4 Diacylglycerol acyltransferase ORC3_N PF07034.6 EMG45349.1 - 9.4e-17 60.9 4.4 9.6e-12 44.5 0.3 2.2 1 1 1 2 2 2 2 Origin recognition complex (ORC) subunit 3 N-terminus DHO_dh PF01180.16 EMG45349.1 - 0.0032 16.4 0.0 0.0057 15.6 0.0 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase CENP-T PF15511.1 EMG45350.1 - 0.011 15.0 10.7 0.01 15.1 7.4 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T IncA PF04156.9 EMG45350.1 - 0.014 15.0 5.4 0.022 14.3 3.7 1.3 1 0 0 1 1 1 0 IncA protein Ycf1 PF05758.7 EMG45350.1 - 0.13 10.0 5.1 0.13 9.9 3.5 1.0 1 0 0 1 1 1 0 Ycf1 OmpH PF03938.9 EMG45350.1 - 0.27 11.1 18.4 0.34 10.8 12.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Asp-B-Hydro_N PF05279.6 EMG45350.1 - 0.63 9.8 24.4 0.78 9.5 16.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AAA_23 PF13476.1 EMG45350.1 - 1.6 8.9 7.4 2.1 8.6 5.1 1.2 1 0 0 1 1 1 0 AAA domain Cytochrome-c551 PF10643.4 EMG45350.1 - 1.8 7.7 9.3 92 2.2 6.4 2.1 1 1 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 FixO PF02433.10 EMG45350.1 - 2.4 7.4 5.2 1 8.6 2.1 1.5 1 1 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO DUF106 PF01956.11 EMG45350.1 - 6.1 6.3 7.0 10 5.5 4.8 1.7 1 1 0 1 1 1 0 Integral membrane protein DUF106 Mannosyl_trans3 PF11051.3 EMG45351.1 - 2e-65 220.8 0.3 4.1e-65 219.8 0.2 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative Grp1_Fun34_YaaH PF01184.14 EMG45352.1 - 4.2e-73 245.1 19.2 4.9e-73 244.9 13.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Aminotran_4 PF01063.14 EMG45353.1 - 6.3e-34 117.4 0.0 8.5e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV AA_permease PF00324.16 EMG45354.1 - 2.4e-48 164.6 25.3 2.7e-48 164.5 17.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG45354.1 - 2.5e-15 55.9 21.6 3.2e-15 55.6 15.0 1.0 1 0 0 1 1 1 1 Amino acid permease Orai-1 PF07856.7 EMG45354.1 - 0.11 12.0 10.4 0.22 11.0 7.2 1.6 1 1 0 1 1 1 0 Mediator of CRAC channel activity LRR_4 PF12799.2 EMG45355.1 - 1.4e-11 43.7 34.7 4.5e-05 22.9 3.1 9.6 7 2 1 8 8 8 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG45355.1 - 2.7e-07 30.2 9.2 2.7e-07 30.2 6.4 7.1 5 2 3 9 9 9 3 Leucine rich repeat LRR_1 PF00560.28 EMG45355.1 - 0.0035 17.1 34.8 0.71 10.1 0.0 9.8 9 3 1 10 10 10 3 Leucine Rich Repeat LRR_7 PF13504.1 EMG45355.1 - 0.008 16.1 22.8 24 5.7 0.1 11.0 15 0 0 15 15 15 2 Leucine rich repeat NIF PF03031.13 EMG45356.1 - 4.5e-51 172.6 0.3 9.7e-51 171.5 0.2 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EMG45356.1 - 0.014 15.6 0.1 0.25 11.5 0.0 2.2 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Clp1 PF06807.9 EMG45358.1 - 1.1e-06 28.5 0.3 1.2e-05 25.1 0.1 2.4 3 0 0 3 3 3 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EMG45358.1 - 0.0017 18.0 0.1 0.026 14.2 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 EMG45358.1 - 0.0068 15.9 0.0 0.0074 15.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain MTS_N PF08468.6 EMG45358.1 - 0.014 15.2 0.1 0.048 13.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain N-terminal ATP_bind_1 PF03029.12 EMG45358.1 - 0.041 13.4 0.1 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 EMG45358.1 - 0.19 11.2 0.1 0.59 9.5 0.1 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family PTPA PF03095.10 EMG45359.1 - 3.3e-117 390.9 0.1 3.8e-117 390.7 0.1 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein LETM1 PF07766.8 EMG45360.1 - 1.6e-05 24.1 1.8 0.0007 18.7 0.1 2.3 2 1 0 2 2 2 2 LETM1-like protein Pox_I1 PF03289.8 EMG45360.1 - 0.023 13.5 1.8 0.074 11.8 0.3 2.1 1 1 1 2 2 2 0 Poxvirus protein I1 Pkinase PF00069.20 EMG45361.1 - 4.9e-79 265.1 0.0 7e-79 264.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG45361.1 - 4.6e-40 137.3 0.0 6.9e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EMG45361.1 - 9.9e-28 96.0 0.3 3.4e-16 59.1 0.1 2.8 2 0 0 2 2 2 2 FHA domain Kinase-like PF14531.1 EMG45361.1 - 4.2e-07 29.2 0.0 9.1e-07 28.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMG45361.1 - 5.3e-05 22.3 0.0 9.6e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMG45361.1 - 0.0048 16.6 0.0 0.019 14.7 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EMG45361.1 - 0.0074 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family PTR2 PF00854.16 EMG45362.1 - 1.4e-53 182.0 16.3 1.8e-53 181.7 11.3 1.1 1 0 0 1 1 1 1 POT family VKOR PF07884.9 EMG45362.1 - 0.003 17.4 1.4 0.003 17.4 1.0 3.3 4 0 0 4 4 4 1 Vitamin K epoxide reductase family PTR2 PF00854.16 EMG45363.1 - 8.8e-53 179.4 17.0 1.4e-52 178.7 11.8 1.3 1 0 0 1 1 1 1 POT family zf-C2H2 PF00096.21 EMG45364.1 - 1.7e-06 28.0 11.6 0.0029 17.8 0.0 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EMG45364.1 - 4.7 7.3 14.1 9.5 6.3 0.1 4.1 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) AA_permease PF00324.16 EMG45365.1 - 5.2e-79 265.7 13.2 6.2e-79 265.5 9.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG45365.1 - 4.9e-19 68.1 13.8 6e-19 67.8 9.5 1.0 1 0 0 1 1 1 1 Amino acid permease Yip1 PF04893.12 EMG45365.1 - 0.13 11.7 15.6 0.013 15.0 4.3 2.2 1 1 1 2 2 2 0 Yip1 domain WD40 PF00400.27 EMG45366.1 - 2.4e-16 58.9 6.1 3.5e-06 26.6 0.2 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat RabGAP-TBC PF00566.13 EMG45367.1 - 1e-35 123.1 8.5 1e-35 123.1 5.9 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Racemase_4 PF13615.1 EMG45367.1 - 0.059 13.6 0.3 3.1 8.0 0.0 2.7 2 0 0 2 2 2 0 Putative alanine racemase Dynamin_M PF01031.15 EMG45368.1 - 1.4e-111 372.0 0.1 3e-111 370.9 0.1 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EMG45368.1 - 8.8e-54 181.8 0.0 8.8e-54 181.8 0.0 2.4 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 EMG45368.1 - 9.5e-31 105.5 4.3 2.7e-30 104.0 3.0 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EMG45368.1 - 0.002 18.0 0.2 0.053 13.4 0.1 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMG45368.1 - 0.0068 15.6 0.3 1.3 8.2 0.1 2.5 2 0 0 2 2 2 2 Ferrous iron transport protein B Chitin_bind_3 PF03067.10 EMG45368.1 - 0.019 15.2 1.2 0.041 14.1 0.4 1.8 2 0 0 2 2 2 0 Chitin binding domain Miro PF08477.8 EMG45368.1 - 0.047 14.2 2.1 0.26 11.7 0.0 3.1 3 1 1 4 4 4 0 Miro-like protein Ribophorin_I PF04597.9 EMG45369.1 - 3.9e-130 434.2 8.1 4.5e-130 434.0 5.6 1.0 1 0 0 1 1 1 1 Ribophorin I Alginate_lyase2 PF08787.6 EMG45369.1 - 0.15 11.6 1.8 0.28 10.8 1.2 1.3 1 0 0 1 1 1 0 Alginate lyase Pro_isomerase PF00160.16 EMG45370.1 - 2.8e-31 108.8 0.4 4.1e-31 108.2 0.3 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Proteasome PF00227.21 EMG45371.1 - 3.4e-46 156.9 1.3 3.8e-46 156.7 0.9 1.0 1 0 0 1 1 1 1 Proteasome subunit Pox_A51 PF04948.8 EMG45371.1 - 0.062 11.9 0.4 0.12 11.0 0.3 1.4 1 0 0 1 1 1 0 Poxvirus A51 protein Lact_bio_phlase PF09508.5 EMG45371.1 - 0.11 10.1 0.3 0.18 9.4 0.1 1.3 2 0 0 2 2 2 0 Lacto-N-biose phosphorylase AA_permease PF00324.16 EMG45372.1 - 9e-46 156.1 24.7 1e-45 156.0 17.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG45372.1 - 2.2e-14 52.8 21.3 2.8e-14 52.5 14.8 1.0 1 0 0 1 1 1 1 Amino acid permease Orai-1 PF07856.7 EMG45372.1 - 1.1 8.7 8.5 2.2 7.8 5.8 1.5 1 1 0 1 1 1 0 Mediator of CRAC channel activity Asp PF00026.18 EMG45373.1 - 2.6e-66 224.0 7.2 1e-65 222.1 5.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMG45373.1 - 4.7e-07 29.9 1.8 0.00017 21.5 0.0 4.0 3 2 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMG45373.1 - 2.4e-06 27.9 0.7 1.1 9.8 0.0 3.7 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EMG45373.1 - 0.0034 16.9 0.1 0.048 13.2 0.1 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal RVP PF00077.15 EMG45373.1 - 0.053 13.4 0.0 1.3 8.9 0.0 2.8 2 0 0 2 2 2 0 Retroviral aspartyl protease DUF3774 PF12609.3 EMG45374.1 - 0.099 13.5 0.1 0.12 13.2 0.1 1.1 1 0 0 1 1 1 0 Wound-induced protein KMP11 PF03037.11 EMG45374.1 - 0.12 13.0 0.1 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 Myosin_head PF00063.16 EMG45376.1 - 3.8e-259 861.4 7.4 3.8e-259 861.4 5.1 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 EMG45376.1 - 8.4e-34 115.6 0.5 5.8e-33 112.9 0.3 2.6 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 EMG45376.1 - 3.5e-16 57.2 33.5 4e-05 22.8 0.2 7.1 7 0 0 7 7 7 6 IQ calmodulin-binding motif AAA_22 PF13401.1 EMG45376.1 - 0.0015 18.7 1.5 0.0088 16.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EMG45376.1 - 0.016 15.1 1.4 0.12 12.3 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Reo_sigmaC PF04582.7 EMG45376.1 - 0.1 11.7 5.9 0.23 10.5 4.1 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein AAA_19 PF13245.1 EMG45376.1 - 0.13 12.0 0.0 0.36 10.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Myosin_N PF02736.14 EMG45376.1 - 0.29 10.8 2.6 0.29 10.8 0.4 2.1 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain BolA PF01722.13 EMG45377.1 - 5e-27 93.6 1.1 7.2e-27 93.1 0.7 1.2 1 0 0 1 1 1 1 BolA-like protein KAR9 PF08580.5 EMG45378.1 - 1.5e-141 472.9 27.4 1.9e-141 472.6 19.0 1.1 1 0 0 1 1 1 1 Yeast cortical protein KAR9 PGM_PMM_I PF02878.11 EMG45380.1 - 4.8e-18 64.9 0.0 6.3e-09 35.4 0.0 2.7 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EMG45380.1 - 9.6e-14 51.5 0.3 2.5e-12 47.0 0.1 2.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EMG45380.1 - 0.0035 17.3 0.0 0.0098 15.9 0.0 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III SNase PF00565.12 EMG45381.1 - 4.2e-23 81.6 0.2 5.6e-23 81.2 0.1 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue ERG2_Sigma1R PF04622.7 EMG45382.1 - 4.8e-78 261.3 0.2 5.6e-78 261.1 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein MFS_1 PF07690.11 EMG45384.1 - 2.7e-33 115.1 74.2 5.1e-25 87.9 30.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG45384.1 - 0.00011 20.8 41.3 0.003 16.2 9.6 3.0 1 1 1 3 3 3 3 Sugar (and other) transporter MFS_1_like PF12832.2 EMG45384.1 - 0.068 12.9 0.3 0.068 12.9 0.2 3.6 4 0 0 4 4 4 0 MFS_1 like family PUA PF01472.15 EMG45385.1 - 0.044 13.5 9.3 0.97 9.2 0.1 4.2 5 0 0 5 5 5 0 PUA domain Ribosomal_S11 PF00411.14 EMG45385.1 - 3 8.0 6.7 20 5.3 0.3 3.1 1 1 2 3 3 3 0 Ribosomal protein S11 DUF3921 PF13060.1 EMG45385.1 - 6.3 6.7 16.1 13 5.7 0.1 5.7 3 2 4 7 7 7 0 Protein of unknown function (DUF3921) Pkinase PF00069.20 EMG45387.1 - 5.6e-47 160.0 0.3 1.1e-46 159.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG45387.1 - 5.1e-20 71.6 0.0 1.3e-19 70.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG45387.1 - 0.00039 19.4 0.0 0.0021 17.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pinin_SDK_memA PF04696.8 EMG45387.1 - 0.003 17.1 3.5 0.003 17.1 2.4 2.0 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region APH PF01636.18 EMG45387.1 - 0.02 14.6 0.0 0.95 9.1 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1690 PF07956.6 EMG45387.1 - 2 8.4 12.3 1.9 8.4 0.2 3.0 2 1 0 3 3 3 0 Protein of Unknown function (DUF1690) Actin PF00022.14 EMG45388.1 - 6.3e-116 387.0 0.0 7.1e-116 386.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EMG45388.1 - 0.0019 16.8 0.0 0.0059 15.2 0.0 1.6 1 1 0 1 1 1 1 MreB/Mbl protein GCD14 PF08704.5 EMG45389.1 - 3e-80 269.2 0.0 4.2e-80 268.7 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit RrnaAD PF00398.15 EMG45389.1 - 0.00042 19.4 0.0 0.00066 18.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.14 EMG45389.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EMG45389.1 - 0.0041 17.6 0.0 0.011 16.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMG45389.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EMG45389.1 - 0.058 12.5 0.0 0.32 10.0 0.0 1.9 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family DUF3616 PF12275.3 EMG45389.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3616) LSM PF01423.17 EMG45390.1 - 1.3e-12 47.0 0.0 2.1e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 LSM domain Acyl-CoA_dh_1 PF00441.19 EMG45391.1 - 7.5e-24 84.5 0.2 1.1e-23 84.0 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMG45391.1 - 6.2e-14 51.2 0.2 3.7e-13 48.7 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EMG45391.1 - 1e-10 42.1 0.0 1.9e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EMG45391.1 - 6.3e-06 26.4 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RPN7 PF10602.4 EMG45392.1 - 1.9e-53 180.4 1.8 1.9e-53 180.4 1.2 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 EMG45392.1 - 4.5e-16 59.0 1.6 8.4e-16 58.2 0.3 2.1 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EMG45392.1 - 3.5e-06 26.8 0.3 9e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 TPR_12 PF13424.1 EMG45392.1 - 0.0041 17.0 0.2 0.052 13.4 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat Interferon PF00143.14 EMG45392.1 - 0.02 14.7 0.2 0.055 13.3 0.2 1.7 1 0 0 1 1 1 0 Interferon alpha/beta domain CSTF2_hinge PF14327.1 EMG45393.1 - 2.8e-22 78.5 1.2 2.8e-22 78.5 0.8 2.2 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EMG45393.1 - 9.3e-08 31.5 0.0 1.8e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG45393.1 - 1.5e-07 31.2 0.0 3.9e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG45393.1 - 0.0007 19.3 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.9 EMG45393.1 - 1.9 8.1 10.7 2.9 7.5 7.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-RING_2 PF13639.1 EMG45394.1 - 6.7e-11 41.8 1.9 7.8e-09 35.2 0.2 2.3 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 EMG45394.1 - 1.8e-09 37.5 0.5 6e-07 29.4 0.2 2.3 2 0 0 2 2 2 2 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMG45394.1 - 9.1e-07 28.4 2.2 2e-05 24.1 0.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMG45394.1 - 4.1e-05 23.5 3.5 0.0008 19.3 0.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMG45394.1 - 6.8e-05 22.6 0.2 0.00036 20.3 0.1 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EMG45394.1 - 0.00032 20.3 0.9 0.0074 15.9 0.2 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMG45394.1 - 0.00034 20.2 2.1 0.0087 15.7 0.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMG45394.1 - 0.083 12.7 4.8 0.055 13.3 0.9 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EMG45394.1 - 0.29 11.1 1.6 11 6.0 0.4 3.0 2 1 0 2 2 2 0 FANCL C-terminal domain zf-Nse PF11789.3 EMG45394.1 - 0.35 10.4 2.0 1 8.8 0.5 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit TraG-D_C PF12696.2 EMG45394.1 - 0.99 9.2 5.0 2.4 8.0 3.5 1.6 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG Chitin_synth_1 PF01644.12 EMG45395.1 - 2.7e-78 261.4 0.5 4.1e-78 260.7 0.4 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EMG45395.1 - 4e-25 87.3 0.0 9.6e-25 86.0 0.0 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EMG45395.1 - 7.6e-24 83.9 6.4 2.3e-16 59.2 0.1 3.1 2 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EMG45395.1 - 3.5e-11 43.1 1.9 3.5e-11 43.1 1.3 2.5 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMG45395.1 - 1e-06 28.7 0.0 3.7e-05 23.6 0.0 2.8 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EMG45395.1 - 0.028 14.0 0.0 4.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 ABC2_membrane_2 PF12679.2 EMG45395.1 - 0.23 10.2 12.5 0.28 10.0 5.8 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein YvrJ PF12841.2 EMG45396.1 - 0.62 9.3 2.6 6.8 6.0 0.2 2.9 3 0 0 3 3 3 0 YvrJ protein family MFS_1 PF07690.11 EMG45397.1 - 2.4e-35 121.8 37.6 2.4e-35 121.8 26.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4642 PF15484.1 EMG45398.1 - 0.0036 17.3 0.5 0.011 15.7 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4642) Glu-tRNAGln PF02686.10 EMG45398.1 - 0.067 12.9 1.2 0.21 11.4 0.3 2.3 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit FAM176 PF14851.1 EMG45398.1 - 0.077 12.6 0.7 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 FAM176 family Pam16 PF03656.8 EMG45398.1 - 0.08 12.7 0.8 0.65 9.8 0.0 2.6 3 0 0 3 3 3 0 Pam16 Band_7 PF01145.20 EMG45399.1 - 5.9e-32 111.0 0.9 8.2e-32 110.5 0.6 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EMG45399.1 - 0.0011 18.5 0.3 0.0017 17.9 0.2 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family Cys_Met_Meta_PP PF01053.15 EMG45400.1 - 4.2e-63 212.9 0.0 9.6e-63 211.7 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EMG45400.1 - 0.0028 16.4 0.0 0.0047 15.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Uma2 PF05685.7 EMG45400.1 - 0.033 13.5 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative restriction endonuclease GDC-P PF02347.11 EMG45400.1 - 0.05 12.3 0.0 0.14 10.8 0.0 1.5 1 1 0 2 2 2 0 Glycine cleavage system P-protein BCDHK_Adom3 PF10436.4 EMG45401.1 - 7.8e-65 217.3 0.0 2.7e-64 215.6 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EMG45401.1 - 5.6e-16 58.2 0.0 1.5e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EMG45401.1 - 0.056 13.1 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Zip PF02535.17 EMG45401.1 - 0.13 11.2 3.7 0.2 10.6 2.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Peroxin-13_N PF04088.8 EMG45402.1 - 3.1e-41 140.9 2.3 3.1e-41 140.9 1.6 1.7 2 0 0 2 2 2 1 Peroxin 13, N-terminal region SH3_9 PF14604.1 EMG45402.1 - 1.1e-07 31.2 0.0 1.8e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMG45402.1 - 2.6e-07 29.8 0.0 4.2e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMG45402.1 - 1.8e-06 27.3 0.0 3.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 EMG45402.1 - 1.4e-05 25.1 0.1 3.3e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Sm_multidrug_ex PF06695.6 EMG45402.1 - 0.029 14.5 0.1 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative small multi-drug export protein SieB PF14163.1 EMG45402.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Superinfection exclusion protein B MGC-24 PF05283.6 EMG45402.1 - 7.2 6.3 12.5 10 5.8 8.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) RVT_2 PF07727.9 EMG45403.1 - 3.7e-27 94.8 0.0 5.7e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF836 PF05768.9 EMG45403.1 - 0.077 13.2 0.0 0.47 10.7 0.0 2.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) CN_hydrolase PF00795.17 EMG45404.1 - 2.7e-22 79.0 0.0 3.9e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase AAA PF00004.24 EMG45404.1 - 0.06 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3875 PF12991.2 EMG45406.1 - 0.012 15.2 0.2 0.91 9.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF3875) Pput2613-deam PF14427.1 EMG45406.1 - 0.12 12.0 11.2 0.47 10.1 0.5 3.1 2 1 2 4 4 4 0 Pput_2613-like deaminase DUF4425 PF14466.1 EMG45406.1 - 8.3 6.5 13.3 12 6.0 2.9 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4425) Hyphal_reg_CWP PF11765.3 EMG45407.1 - 5.3e-91 304.8 11.1 6.7e-91 304.5 7.7 1.1 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Pribosyltran_N PF13793.1 EMG45409.1 - 1.9e-40 137.1 0.0 1e-39 134.8 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EMG45409.1 - 2.1e-39 135.1 2.6 2.1e-37 128.6 1.8 2.3 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EMG45409.1 - 1e-07 31.6 0.3 1.1e-06 28.4 0.2 2.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain PNP_UDP_1 PF01048.15 EMG45409.1 - 0.038 12.9 0.0 0.069 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphorylase superfamily HSF_DNA-bind PF00447.12 EMG45410.1 - 2.9e-36 123.7 1.3 6.1e-36 122.7 0.9 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 EMG45410.1 - 6.6e-25 87.2 0.1 1.9e-24 85.8 0.1 1.8 2 0 0 2 2 2 1 Response regulator receiver domain HALZ PF02183.13 EMG45410.1 - 0.0034 17.0 0.6 0.0065 16.1 0.4 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper ADIP PF11559.3 EMG45410.1 - 0.01 15.7 1.3 0.02 14.8 0.9 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spermine_synth PF01564.12 EMG45410.1 - 0.03 13.2 1.2 0.039 12.8 0.1 1.6 2 0 0 2 2 2 0 Spermine/spermidine synthase DUF972 PF06156.8 EMG45410.1 - 0.055 13.8 0.5 0.13 12.6 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) TMF_DNA_bd PF12329.3 EMG45410.1 - 0.075 12.8 0.7 0.17 11.7 0.5 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding bZIP_2 PF07716.10 EMG45410.1 - 0.23 11.2 1.4 0.45 10.3 1.0 1.4 1 0 0 1 1 1 0 Basic region leucine zipper DivIC PF04977.10 EMG45410.1 - 8.5 5.9 7.5 0.18 11.2 0.3 1.8 2 0 0 2 2 2 0 Septum formation initiator Glyco_hydro_31 PF01055.21 EMG45411.1 - 1.1e-148 495.7 2.4 1.5e-148 495.3 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EMG45411.1 - 2.2e-21 75.4 0.5 2.6e-20 72.0 0.0 2.7 2 0 0 2 2 2 1 Galactose mutarotase-like GIY-YIG PF01541.19 EMG45412.1 - 2.1e-10 40.8 0.0 3.7e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain T5orf172 PF10544.4 EMG45412.1 - 0.0034 17.7 0.1 0.0079 16.5 0.1 1.7 1 1 0 1 1 1 1 T5orf172 domain BRE1 PF08647.6 EMG45413.1 - 1.4e-24 85.8 14.8 1.4e-24 85.8 10.3 6.9 4 3 1 5 5 2 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 EMG45413.1 - 9e-08 32.0 8.7 1.6e-07 31.2 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMG45413.1 - 4.7e-07 29.3 7.2 7.7e-07 28.6 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMG45413.1 - 2.2e-06 27.2 8.2 4.2e-06 26.3 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMG45413.1 - 1.3e-05 24.8 9.4 2.1e-05 24.1 6.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EMG45413.1 - 0.0002 21.1 8.0 0.00036 20.3 5.6 1.4 1 0 0 1 1 1 1 Ring finger domain Phage_GPO PF05929.6 EMG45413.1 - 0.0053 16.0 7.0 0.0053 16.0 4.9 5.4 1 1 3 6 6 6 1 Phage capsid scaffolding protein (GPO) serine peptidase zf-RING_6 PF14835.1 EMG45413.1 - 0.018 14.8 3.4 0.04 13.6 2.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EMG45413.1 - 0.021 14.5 3.9 0.089 12.5 2.7 2.2 1 0 0 1 1 1 0 RING-type zinc-finger DUF1192 PF06698.6 EMG45413.1 - 0.022 14.5 0.3 0.022 14.5 0.2 5.1 4 1 1 5 5 5 0 Protein of unknown function (DUF1192) Flagellin_D3 PF08884.6 EMG45413.1 - 0.04 14.0 0.1 0.14 12.3 0.1 1.9 1 0 0 1 1 1 0 Flagellin D3 domain zf-C3HC4_4 PF15227.1 EMG45413.1 - 0.051 13.4 6.1 0.1 12.5 4.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Pyrophosphatase PF00719.14 EMG45413.1 - 0.052 13.0 4.6 0.04 13.3 0.4 2.6 1 1 1 2 2 2 0 Inorganic pyrophosphatase Prok-RING_4 PF14447.1 EMG45413.1 - 0.11 11.9 2.8 0.28 10.7 1.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF1272 PF06906.6 EMG45413.1 - 0.13 12.1 4.9 0.26 11.1 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C2H2 PF00096.21 EMG45413.1 - 0.16 12.3 0.0 0.16 12.3 0.0 2.9 3 0 0 3 3 2 0 Zinc finger, C2H2 type zf-rbx1 PF12678.2 EMG45413.1 - 0.24 11.5 3.9 0.49 10.5 2.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger Ret_tiss PF10044.4 EMG45413.1 - 0.26 11.8 0.1 0.26 11.8 0.0 4.7 5 2 0 5 5 4 0 Retinal tissue protein zf-RING_4 PF14570.1 EMG45413.1 - 0.58 9.7 6.1 1.1 8.8 4.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc_ribbon_4 PF13717.1 EMG45413.1 - 1 9.0 9.2 1.4 8.6 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EMG45413.1 - 1.6 8.4 9.4 1.8 8.2 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain FYVE PF01363.16 EMG45413.1 - 3.6 7.5 10.4 29 4.6 7.3 2.3 1 1 0 1 1 1 0 FYVE zinc finger HypA PF01155.14 EMG45413.1 - 9.3 5.9 11.5 1.9e+02 1.7 6.9 3.2 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Bromodomain PF00439.20 EMG45414.1 - 9.9e-42 140.7 3.9 3.4e-21 74.9 0.2 2.7 2 0 0 2 2 2 2 Bromodomain His_Phos_2 PF00328.17 EMG45416.1 - 3.5e-128 427.7 0.2 4.7e-128 427.3 0.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EMG45416.1 - 1.2e-07 31.3 0.0 2.6e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Acyl_transf_1 PF00698.16 EMG45417.1 - 1.2e-84 284.4 0.0 2.9e-84 283.1 0.0 1.6 2 0 0 2 2 2 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EMG45417.1 - 4.5e-42 142.3 0.0 9.2e-42 141.3 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 EMG45417.1 - 6.8e-30 102.6 0.0 1.7e-29 101.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EMG45417.1 - 9.1e-15 54.6 0.0 2.5e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase Asn_synthase PF00733.16 EMG45417.1 - 0.091 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase RNA_pol_Rpb1_5 PF04998.12 EMG45417.1 - 0.16 11.2 2.1 3.3 6.8 0.1 2.9 2 1 0 3 3 3 0 RNA polymerase Rpb1, domain 5 Arm PF00514.18 EMG45418.1 - 1.7e-84 275.0 16.4 8.9e-12 44.3 0.1 8.7 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMG45418.1 - 2.1e-22 79.2 0.1 0.00051 20.2 0.0 6.1 1 1 3 5 5 5 5 HEAT repeats IBB PF01749.15 EMG45418.1 - 3.2e-21 75.2 7.2 7.3e-21 74.1 5.0 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 EMG45418.1 - 9.2e-21 73.7 0.5 5.1e-06 26.8 0.1 5.8 3 2 3 6 6 6 4 HEAT-like repeat HEAT PF02985.17 EMG45418.1 - 8.4e-15 53.4 0.4 0.016 15.2 0.0 7.7 8 1 0 8 8 8 3 HEAT repeat V-ATPase_H_C PF11698.3 EMG45418.1 - 3.5e-07 30.1 0.0 0.5 10.3 0.0 4.4 4 1 0 4 4 4 3 V-ATPase subunit H Arm_2 PF04826.8 EMG45418.1 - 4.5e-07 29.2 0.7 0.43 9.6 0.0 4.3 1 1 5 6 6 6 4 Armadillo-like Proteasom_PSMB PF10508.4 EMG45418.1 - 2.4e-06 26.1 1.0 0.011 14.0 0.0 3.5 2 2 2 4 4 4 3 Proteasome non-ATPase 26S subunit RICTOR_V PF14668.1 EMG45418.1 - 4.1e-06 26.6 3.7 0.31 11.0 0.0 5.6 5 2 2 7 7 7 1 Rapamycin-insensitive companion of mTOR, domain 5 Adaptin_N PF01602.15 EMG45418.1 - 5.7e-06 24.9 0.8 0.0015 16.9 0.1 2.9 1 1 2 3 3 3 3 Adaptin N terminal region DUF2505 PF10698.4 EMG45418.1 - 0.012 15.0 0.0 3 7.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2505) Usp PF00582.21 EMG45419.1 - 7.2e-12 45.6 0.0 1.1e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 Universal stress protein family TGS PF02824.16 EMG45420.1 - 2.5e-11 43.2 0.0 3.8e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 TGS domain Ribosomal_L14 PF00238.14 EMG45421.1 - 3.1e-49 165.7 1.6 3.4e-49 165.6 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Paramyxo_PNT PF13825.1 EMG45421.1 - 0.011 15.0 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus PAS_3 PF08447.6 EMG45421.1 - 0.072 13.1 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 PAS fold UPF0029 PF01205.14 EMG45422.1 - 6.3e-31 106.3 0.0 7.7e-31 106.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF77 PF01910.12 EMG45425.1 - 6.1e-20 70.6 0.0 6.8e-20 70.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 PVL_ORF50 PF07768.6 EMG45426.1 - 3.9 7.4 10.8 7 6.6 0.5 2.8 3 0 0 3 3 3 0 PVL ORF-50-like family Gp_dh_C PF02800.15 EMG45427.1 - 2.4e-72 241.5 0.0 3.2e-72 241.1 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EMG45427.1 - 6.8e-62 207.8 0.1 1e-61 207.3 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EMG45427.1 - 0.0061 16.4 0.6 0.014 15.2 0.2 1.9 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 EMG45427.1 - 0.053 12.6 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 EMG45428.1 - 1.3e-51 174.0 0.1 4.4e-32 110.7 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 EMG45428.1 - 1.3e-44 151.3 0.0 3.9e-44 149.8 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EMG45428.1 - 5e-38 128.4 3.7 3.3e-25 87.4 0.2 3.1 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EMG45428.1 - 1.6e-25 88.2 1.3 7.3e-21 73.2 0.1 2.6 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Hexapep_2 PF14602.1 EMG45428.1 - 1e-10 40.9 11.7 1.2e-09 37.5 4.8 3.0 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 EMG45428.1 - 1.2e-10 40.3 11.0 2.4e-09 36.2 4.1 2.9 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 EMG45428.1 - 6.8e-09 35.6 0.1 2.1e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 Maltose acetyltransferase TBPIP_N PF15517.1 EMG45428.1 - 0.029 14.0 0.0 0.078 12.6 0.0 1.7 1 0 0 1 1 1 0 TBP-interacting protein N-terminus CENP-L PF13092.1 EMG45429.1 - 0.044 13.5 0.2 0.15 11.8 0.1 2.0 1 1 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 PMT PF02366.13 EMG45430.1 - 3.7e-92 308.1 18.7 3.7e-92 308.1 13.0 2.8 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EMG45430.1 - 6.6e-27 94.2 0.2 1.3e-26 93.3 0.2 1.5 1 0 0 1 1 1 1 MIR domain DUF202 PF02656.10 EMG45430.1 - 0.59 10.3 3.6 4.4 7.5 0.0 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Fe-S_biosyn PF01521.15 EMG45431.1 - 2.3e-15 56.5 0.1 3.2e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis HEAT PF02985.17 EMG45432.1 - 2.9e-40 132.7 19.0 0.0033 17.3 0.0 13.1 13 0 0 13 13 13 9 HEAT repeat HEAT_2 PF13646.1 EMG45432.1 - 3.3e-28 97.7 0.1 2.9e-08 33.8 0.0 8.0 4 3 4 8 8 8 8 HEAT repeats Vac14_Fab1_bd PF12755.2 EMG45432.1 - 2.8e-08 34.0 5.9 0.0022 18.3 0.0 7.4 5 2 5 10 10 10 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EMG45432.1 - 0.00066 20.0 12.1 2.1 8.9 0.0 8.5 6 4 4 10 10 10 1 HEAT-like repeat Trp_Tyr_perm PF03222.8 EMG45432.1 - 0.028 13.2 0.0 0.054 12.3 0.0 1.4 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family Ecm29 PF13001.2 EMG45432.1 - 0.38 9.1 11.7 1.1 7.6 0.7 3.9 3 2 2 5 5 5 0 Proteasome stabiliser DUF2435 PF10363.4 EMG45432.1 - 1.3 8.9 12.2 0.56 10.1 0.2 5.6 6 2 1 7 7 7 0 Protein of unknown function (DUF2435) His_Phos_1 PF00300.17 EMG45433.1 - 5.4e-15 55.8 0.2 1.3e-14 54.6 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.17 EMG45434.1 - 1.4e-15 57.7 0.2 3.6e-15 56.4 0.1 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Brr6_like_C_C PF10104.4 EMG45435.1 - 2e-38 130.9 6.4 2.7e-38 130.5 4.4 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Herpes_UL45 PF05473.7 EMG45435.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.4 1 1 0 1 1 1 0 UL45 protein LemA PF04011.7 EMG45435.1 - 0.035 13.2 0.7 0.073 12.1 0.1 1.8 2 0 0 2 2 2 0 LemA family ABC_membrane PF00664.18 EMG45436.1 - 2e-74 250.4 37.8 2.1e-39 135.5 12.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMG45436.1 - 5.7e-57 191.8 0.1 1.2e-27 96.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMG45436.1 - 4.8e-18 65.2 4.2 1.5e-05 24.3 0.0 4.6 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMG45436.1 - 4.6e-10 39.9 21.6 4.3e-08 33.4 2.5 4.9 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.1 EMG45436.1 - 6.2e-09 35.2 0.1 0.00097 18.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EMG45436.1 - 2.3e-07 30.1 0.0 0.0066 15.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EMG45436.1 - 3.8e-06 27.2 2.1 0.029 14.6 0.0 4.5 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.1 EMG45436.1 - 2.9e-05 24.5 8.4 0.011 16.0 0.1 3.3 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EMG45436.1 - 4.1e-05 24.3 0.9 0.031 15.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EMG45436.1 - 0.00014 22.0 0.8 3 8.0 0.0 4.0 3 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EMG45436.1 - 0.0002 21.1 0.3 1.1 9.2 0.0 3.1 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 EMG45436.1 - 0.00057 19.0 13.8 0.086 11.8 0.1 4.0 2 2 1 4 4 4 2 AAA ATPase domain DUF87 PF01935.12 EMG45436.1 - 0.0022 17.8 0.4 0.22 11.3 0.1 2.9 2 0 0 2 2 2 1 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 EMG45436.1 - 0.0025 17.7 0.1 0.27 11.1 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 EMG45436.1 - 0.0031 17.2 0.1 0.082 12.6 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EMG45436.1 - 0.0051 16.6 0.1 0.67 9.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EMG45436.1 - 0.0064 15.9 0.0 0.85 9.0 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.1 EMG45436.1 - 0.0072 16.3 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 EMG45436.1 - 0.008 15.6 1.6 2.2 7.6 0.0 3.7 4 0 0 4 4 4 1 AAA-like domain ABC_ATPase PF09818.4 EMG45436.1 - 0.0085 14.7 0.0 0.16 10.4 0.0 2.7 3 0 0 3 3 3 1 Predicted ATPase of the ABC class RseC_MucC PF04246.7 EMG45436.1 - 0.022 14.3 3.6 0.47 10.0 0.1 2.7 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Miro PF08477.8 EMG45436.1 - 0.03 14.8 0.1 2.2 8.7 0.1 2.8 2 0 0 2 2 2 0 Miro-like protein Zeta_toxin PF06414.7 EMG45436.1 - 0.033 13.2 0.0 1.1 8.3 0.0 2.7 3 0 0 3 3 2 0 Zeta toxin CbiA PF01656.18 EMG45436.1 - 0.077 12.3 0.0 6.2 6.1 0.0 2.8 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.1 EMG45436.1 - 0.082 12.4 0.0 22 4.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain Trp_repressor PF01371.14 EMG45436.1 - 0.086 12.7 0.3 0.35 10.8 0.0 2.2 2 0 0 2 2 1 0 Trp repressor protein T2SE PF00437.15 EMG45436.1 - 0.11 11.3 0.0 1.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Zn_clus PF00172.13 EMG45437.1 - 6e-09 35.6 15.2 9.7e-09 34.9 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 EMG45438.1 - 9.7e-50 168.9 0.0 1.2e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cullin PF00888.17 EMG45439.1 - 6.9e-36 123.9 17.8 6.5e-35 120.7 12.4 2.3 1 1 0 1 1 1 1 Cullin family APC2 PF08672.6 EMG45439.1 - 5.2e-18 65.0 1.9 1.9e-17 63.2 1.3 2.1 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 FeoC PF09012.5 EMG45439.1 - 0.036 13.7 0.0 0.19 11.4 0.0 2.3 1 0 0 1 1 1 0 FeoC like transcriptional regulator OB_NTP_bind PF07717.11 EMG45440.1 - 3.2e-17 62.3 0.0 1.1e-16 60.6 0.0 2.1 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EMG45440.1 - 9.9e-17 60.8 0.0 7.2e-16 58.0 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EMG45440.1 - 5.9e-15 54.8 0.1 1.6e-14 53.5 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMG45440.1 - 6.5e-12 45.2 1.3 3e-11 43.0 0.4 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase RWD PF05773.17 EMG45440.1 - 4.9e-08 32.8 1.0 1.9e-07 30.9 0.7 2.2 1 1 0 1 1 1 1 RWD domain AAA_29 PF13555.1 EMG45440.1 - 0.0008 18.8 0.6 0.0023 17.4 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EMG45440.1 - 0.0014 18.7 0.1 0.0066 16.5 0.1 2.2 1 0 0 1 1 1 1 AAA domain DND1_DSRM PF14709.1 EMG45440.1 - 0.0015 18.7 0.1 0.0041 17.3 0.1 1.8 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 KaiC PF06745.8 EMG45440.1 - 0.0025 16.9 1.3 0.005 15.9 0.0 2.0 2 0 0 2 2 2 1 KaiC T2SE PF00437.15 EMG45440.1 - 0.0026 16.7 0.1 0.0057 15.5 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.11 EMG45440.1 - 0.0026 17.0 0.1 0.011 14.9 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.1 EMG45440.1 - 0.0051 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EMG45440.1 - 0.028 14.3 0.0 0.091 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EMG45440.1 - 0.032 13.7 0.0 0.1 12.0 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family UBA PF00627.26 EMG45440.1 - 0.085 12.7 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain AAA_25 PF13481.1 EMG45440.1 - 0.092 12.1 0.0 0.37 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Cullin_binding PF03556.10 EMG45441.1 - 1.5e-22 79.9 7.7 1.5e-22 79.9 5.3 1.9 1 1 1 2 2 2 1 Cullin binding UBA_4 PF14555.1 EMG45441.1 - 4.8e-09 35.5 0.0 9.9e-09 34.6 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain DAG_kinase_N PF14513.1 EMG45441.1 - 0.36 11.0 4.8 0.27 11.4 0.2 2.4 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus HalX PF08663.5 EMG45442.1 - 0.057 13.4 0.3 0.099 12.6 0.2 1.3 1 0 0 1 1 1 0 HalX domain DUF4140 PF13600.1 EMG45442.1 - 0.31 11.4 2.3 0.47 10.9 1.6 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) MIP-T3 PF10243.4 EMG45442.1 - 1.6 7.1 19.8 1.8 6.9 13.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Macoilin PF09726.4 EMG45442.1 - 2.2 6.4 14.7 2.4 6.3 10.2 1.1 1 0 0 1 1 1 0 Transmembrane protein CAML PF14963.1 EMG45442.1 - 3.8 6.8 8.5 4.1 6.7 5.9 1.0 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Ndc1_Nup PF09531.5 EMG45442.1 - 4.1 5.6 15.8 4.9 5.4 10.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Nnf1 PF03980.9 EMG45442.1 - 4.1 7.4 5.9 0.41 10.6 0.8 1.7 2 0 0 2 2 2 0 Nnf1 Pneumo_att_G PF05539.6 EMG45442.1 - 7.3 5.8 12.1 7.4 5.8 8.4 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Slu7 PF11708.3 EMG45443.1 - 1.5e-49 168.9 15.9 3.3e-48 164.5 11.0 2.1 1 1 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor HLH PF00010.21 EMG45445.1 - 4.3e-09 35.9 5.1 4.3e-09 35.9 3.5 2.5 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain HNH PF01844.18 EMG45445.1 - 0.2 11.5 0.8 5.4 6.9 0.0 2.5 2 0 0 2 2 2 0 HNH endonuclease AA_permease PF00324.16 EMG45447.1 - 2e-49 168.2 46.7 2.5e-49 167.9 32.4 1.1 1 0 0 1 1 1 1 Amino acid permease MULE PF10551.4 EMG45448.1 - 0.017 15.2 0.0 0.049 13.7 0.0 1.8 1 0 0 1 1 1 0 MULE transposase domain DEAD PF00270.24 EMG45449.1 - 3.2e-45 153.6 0.1 6.9e-45 152.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG45449.1 - 1.6e-21 75.9 0.0 6.9e-21 73.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EMG45449.1 - 3.1e-06 26.2 0.0 5.9e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ECH PF00378.15 EMG45450.1 - 8e-28 97.1 0.0 1e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Autophagy_Cterm PF10381.4 EMG45450.1 - 0.02 13.9 0.3 0.047 12.8 0.2 1.5 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal ATP13 PF12921.2 EMG45451.1 - 3.5e-24 84.5 0.1 1.4e-23 82.5 0.1 2.1 1 0 0 1 1 1 1 Mitochondrial ATPase expression DUF637 PF04830.8 EMG45451.1 - 0.071 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Possible hemagglutinin (DUF637) SecE PF00584.15 EMG45452.1 - 1e-05 25.0 0.0 1.2e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DUF4295 PF14128.1 EMG45452.1 - 0.0057 16.2 0.1 0.0083 15.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4295) CofC PF01983.11 EMG45452.1 - 0.074 12.0 0.0 0.076 11.9 0.0 1.1 1 0 0 1 1 1 0 Guanylyl transferase CofC like Nop52 PF05997.7 EMG45453.1 - 5.5e-68 228.6 2.1 6.5e-68 228.4 1.5 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Occludin_ELL PF07303.8 EMG45453.1 - 0.05 14.3 0.0 0.12 13.1 0.0 1.5 1 0 0 1 1 1 0 Occludin homology domain SLD3 PF08639.5 EMG45454.1 - 4.2e-70 236.8 33.1 9.8e-70 235.5 22.9 1.7 1 1 0 1 1 1 1 DNA replication regulator SLD3 DUF1546 PF07571.8 EMG45455.1 - 2.7e-29 101.1 0.1 6.4e-29 99.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 EMG45455.1 - 3.6e-24 84.4 0.4 9.4e-24 83.1 0.1 1.9 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EMG45455.1 - 6.4e-07 29.4 0.1 3.9e-06 26.8 0.1 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMG45455.1 - 0.0022 17.9 0.8 0.0046 16.9 0.2 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FliD_C PF07195.7 EMG45458.1 - 0.028 13.7 4.7 0.041 13.1 3.3 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Sec20 PF03908.8 EMG45458.1 - 1.7 8.4 4.3 1.9 8.2 1.1 2.2 1 1 1 2 2 2 0 Sec20 CCDC-167 PF15188.1 EMG45458.1 - 9.7 6.2 10.7 76 3.3 7.4 2.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Pkinase PF00069.20 EMG45459.1 - 6e-60 202.5 0.0 9.9e-60 201.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG45459.1 - 1.4e-19 70.1 0.0 2.2e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG45459.1 - 5.6e-07 28.8 0.0 1.2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PAS_9 PF13426.1 EMG45459.1 - 5.8e-06 26.6 0.0 0.0096 16.2 0.0 3.0 2 0 0 2 2 2 2 PAS domain Kdo PF06293.9 EMG45459.1 - 0.0061 15.6 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_4 PF08448.5 EMG45459.1 - 0.01 15.8 0.0 0.034 14.1 0.0 1.8 2 0 0 2 2 2 0 PAS fold APH PF01636.18 EMG45459.1 - 0.016 14.9 0.1 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAS PF00989.19 EMG45459.1 - 0.058 13.1 0.0 13 5.6 0.0 2.7 2 0 0 2 2 2 0 PAS fold Macoilin PF09726.4 EMG45460.1 - 4.3 5.4 16.0 5.4 5.1 11.1 1.2 1 0 0 1 1 1 0 Transmembrane protein ABC2_membrane PF01061.19 EMG45461.1 - 2.1e-86 288.4 58.5 3.3e-45 153.8 16.1 2.8 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 EMG45461.1 - 8.2e-40 134.6 0.8 2.6e-34 116.9 0.0 3.2 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 EMG45461.1 - 3.6e-24 85.6 0.0 9.8e-19 68.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 EMG45461.1 - 8.2e-06 25.0 0.2 3.3e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EMG45461.1 - 8.2e-05 22.0 0.0 0.00018 20.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EMG45461.1 - 0.00037 19.6 36.3 0.0027 16.8 10.1 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.1 EMG45461.1 - 0.0005 20.0 0.0 0.00099 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 EMG45461.1 - 0.0053 16.7 0.0 0.13 12.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EMG45461.1 - 0.0079 16.1 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EMG45461.1 - 0.0096 15.4 0.1 0.026 14.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EMG45461.1 - 0.011 14.7 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.14 EMG45461.1 - 0.034 13.3 0.0 0.75 8.9 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_13 PF13166.1 EMG45461.1 - 0.038 12.4 0.0 1.3 7.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 EMG45461.1 - 0.049 13.9 0.2 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EMG45461.1 - 0.051 13.9 1.4 0.13 12.5 0.1 2.1 1 1 1 2 2 2 0 AAA domain ABC_ATPase PF09818.4 EMG45461.1 - 0.054 12.0 0.0 0.082 11.4 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_17 PF13207.1 EMG45461.1 - 0.056 14.2 0.1 0.17 12.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain cobW PF02492.14 EMG45461.1 - 0.057 12.8 0.2 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EMG45461.1 - 0.1 12.7 0.0 0.35 10.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMG45461.1 - 0.19 11.4 0.0 0.47 10.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain PEMT PF04191.8 EMG45462.1 - 4.2e-34 116.8 4.1 9.4e-34 115.7 2.8 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase Sugar_tr PF00083.19 EMG45463.1 - 5.7e-36 124.0 30.0 7.9e-36 123.5 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG45463.1 - 5.3e-32 110.8 51.4 4.4e-30 104.5 21.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily UCR_UQCRX_QCR9 PF05365.7 EMG45463.1 - 0.21 11.2 3.6 1.4 8.5 0.0 3.2 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Saccharop_dh PF03435.13 EMG45464.1 - 2.6e-129 431.5 0.0 3e-129 431.3 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EMG45464.1 - 2.1e-06 27.9 0.2 4.4e-06 26.8 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EMG45464.1 - 0.00012 22.0 0.1 0.00019 21.4 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EMG45464.1 - 0.00051 20.3 0.2 0.001 19.3 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EMG45464.1 - 0.0028 17.5 0.5 0.0072 16.2 0.4 1.6 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 EMG45464.1 - 0.0084 16.6 0.1 0.021 15.3 0.1 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.13 EMG45464.1 - 0.02 14.9 0.7 0.048 13.6 0.5 1.7 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_3 PF03447.11 EMG45464.1 - 0.034 14.5 0.4 0.066 13.6 0.3 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Tubulin_3 PF14881.1 EMG45465.1 - 1.3e-28 99.7 0.2 2.5e-28 98.7 0.2 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 EMG45465.1 - 1.5e-20 73.3 0.2 6.3e-20 71.3 0.1 2.0 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 EMG45465.1 - 1.2e-06 28.5 0.0 5.7e-05 23.0 0.0 2.4 2 1 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Trypan_PARP PF05887.6 EMG45466.1 - 7.5 6.3 18.8 0.54 10.0 2.2 2.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Ribosomal_L7Ae PF01248.21 EMG45467.1 - 4.7e-23 80.5 0.6 7.9e-23 79.8 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EMG45467.1 - 0.0027 17.5 0.1 0.0043 16.9 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 RNA_pol_Rpb1_6 PF04992.9 EMG45468.1 - 0.88 9.2 7.7 0.2 11.3 1.4 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 6 Sugar_tr PF00083.19 EMG45469.1 - 3.6e-97 325.7 12.9 4.6e-97 325.4 8.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG45469.1 - 6.6e-32 110.5 24.2 6.6e-32 110.5 16.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ELO PF01151.13 EMG45470.1 - 1.6e-66 224.1 13.2 2.1e-66 223.7 9.1 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family KH_1 PF00013.24 EMG45471.1 - 1.1e-11 44.2 3.6 3e-08 33.1 0.0 4.3 5 0 0 5 5 5 2 KH domain KH_3 PF13014.1 EMG45471.1 - 2e-11 43.2 0.1 4.3e-06 26.2 0.1 4.5 4 0 0 4 4 4 2 KH domain SLS PF14611.1 EMG45471.1 - 0.0021 17.5 6.1 0.12 11.8 0.2 3.6 2 1 0 3 3 3 2 Mitochondrial inner-membrane-bound regulator UDG PF03167.14 EMG45472.1 - 3.6e-10 39.5 0.0 4.3e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Vac_ImportDeg PF09783.4 EMG45474.1 - 2.4e-56 190.0 2.9 2.4e-56 190.0 2.0 1.9 2 0 0 2 2 2 1 Vacuolar import and degradation protein DHC_N2 PF08393.8 EMG45477.1 - 1e-114 383.2 20.5 1e-114 383.2 14.2 6.4 7 0 0 7 7 6 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.7 EMG45477.1 - 2.1e-96 323.6 33.4 2.1e-96 323.6 23.2 7.1 6 1 1 7 7 5 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.2 EMG45477.1 - 9.8e-67 224.8 0.0 3.1e-66 223.2 0.0 1.9 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 Dynein_heavy PF03028.10 EMG45477.1 - 1.6e-61 208.3 0.2 1.6e-61 208.3 0.1 2.5 3 0 0 3 3 2 1 Dynein heavy chain and region D6 of dynein motor MT PF12777.2 EMG45477.1 - 2.5e-31 108.6 3.4 2.5e-31 108.6 2.4 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 EMG45477.1 - 2.1e-28 98.7 5.4 2.3e-28 98.6 0.2 3.2 3 0 0 3 3 3 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 EMG45477.1 - 6.1e-26 91.1 0.1 4e-24 85.1 0.0 3.3 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 EMG45477.1 - 1.3e-25 89.7 0.2 8e-10 38.5 0.0 6.1 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA_8 PF12780.2 EMG45477.1 - 6.8e-25 87.5 0.2 6.8e-25 87.5 0.1 3.0 4 0 0 4 4 4 1 P-loop containing dynein motor region D4 AAA PF00004.24 EMG45477.1 - 6.8e-15 55.4 2.9 0.0014 18.7 0.0 5.9 5 0 0 5 5 4 4 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMG45477.1 - 2.3e-13 50.4 12.8 0.0074 16.4 0.0 8.5 10 0 0 10 10 7 3 AAA domain AAA_17 PF13207.1 EMG45477.1 - 3.7e-13 50.3 1.5 0.0086 16.8 0.0 6.4 5 0 0 5 5 4 3 AAA domain AAA_16 PF13191.1 EMG45477.1 - 2.8e-11 43.7 0.0 0.12 12.4 0.0 5.1 4 0 0 4 4 4 3 AAA ATPase domain AAA_33 PF13671.1 EMG45477.1 - 3.2e-11 43.2 0.0 0.088 12.6 0.0 4.7 4 0 0 4 4 4 3 AAA domain AAA_29 PF13555.1 EMG45477.1 - 5e-09 35.5 0.1 0.0031 17.0 0.0 4.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_18 PF13238.1 EMG45477.1 - 3.3e-07 30.6 6.9 0.59 10.4 0.0 6.7 6 0 0 6 6 4 2 AAA domain T2SE PF00437.15 EMG45477.1 - 4.1e-07 29.1 0.4 0.23 10.3 0.0 3.8 4 0 0 4 4 4 3 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EMG45477.1 - 6.6e-07 29.0 0.3 0.11 11.9 0.0 5.2 5 0 0 5 5 5 1 FtsK/SpoIIIE family AAA_19 PF13245.1 EMG45477.1 - 1.9e-06 27.4 0.6 1.5 8.6 0.0 4.9 5 0 0 5 5 5 1 Part of AAA domain Mg_chelatase PF01078.16 EMG45477.1 - 6.5e-06 25.4 2.1 0.35 9.9 0.0 4.0 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 EMG45477.1 - 1e-05 25.1 0.0 0.41 10.1 0.0 4.7 5 0 0 5 5 5 1 AAA domain ABC_tran PF00005.22 EMG45477.1 - 2.1e-05 24.8 10.2 0.019 15.2 0.0 6.2 6 0 0 6 6 5 1 ABC transporter RNA_helicase PF00910.17 EMG45477.1 - 3.2e-05 24.0 0.9 3.1 8.0 0.0 6.1 6 0 0 6 6 5 1 RNA helicase AAA_25 PF13481.1 EMG45477.1 - 6.8e-05 22.3 0.0 7.8 5.8 0.0 3.9 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 EMG45477.1 - 9.3e-05 21.6 0.1 2.8 6.9 0.0 4.2 4 0 0 4 4 4 2 Zeta toxin AAA_10 PF12846.2 EMG45477.1 - 0.0001 21.8 2.8 0.88 8.9 0.1 4.3 3 0 0 3 3 3 2 AAA-like domain DUF258 PF03193.11 EMG45477.1 - 0.00029 20.0 0.2 0.2 10.8 0.0 3.7 4 0 0 4 4 3 1 Protein of unknown function, DUF258 MobB PF03205.9 EMG45477.1 - 0.068 12.8 5.5 1.4 8.6 0.1 4.0 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_trans_N PF14510.1 EMG45478.1 - 3.2e-28 97.6 1.2 3.4e-28 97.5 0.0 1.6 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal ABC_tran PF00005.22 EMG45478.1 - 4.3e-08 33.5 0.0 9.7e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_25 PF13481.1 EMG45478.1 - 0.037 13.4 0.0 0.078 12.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EMG45478.1 - 0.042 14.1 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMG45478.1 - 0.046 13.4 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain SH3_1 PF00018.23 EMG45479.1 - 2.6e-10 39.5 0.0 7.1e-10 38.1 0.0 1.8 1 0 0 1 1 1 1 SH3 domain PX PF00787.19 EMG45479.1 - 4.1e-09 36.2 0.6 4.1e-09 36.2 0.4 3.0 3 0 0 3 3 3 1 PX domain SH3_9 PF14604.1 EMG45479.1 - 3.4e-07 29.7 0.0 7.2e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMG45479.1 - 2.4e-05 23.7 0.0 5.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF221 PF02714.10 EMG45480.1 - 6.4e-100 334.1 31.8 6.4e-100 334.1 22.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EMG45480.1 - 1.2e-36 125.6 9.8 1.2e-36 125.6 6.8 2.6 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EMG45480.1 - 7.5e-07 29.5 0.3 1.5e-06 28.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Zn_clus PF00172.13 EMG45481.1 - 9.4e-07 28.6 5.9 1.5e-06 27.9 4.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EMG45485.1 - 1.6e-70 237.2 0.4 2.1e-70 236.8 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG45485.1 - 7.9e-37 126.7 0.0 1.1e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG45485.1 - 0.00023 20.2 0.0 0.00032 19.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 EMG45485.1 - 0.00033 21.0 0.4 0.0009 19.7 0.2 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain RhoGAP PF00620.22 EMG45486.1 - 4.7e-43 146.4 0.4 2.4e-42 144.0 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 EMG45486.1 - 1.4e-12 47.6 0.6 6.3e-12 45.5 0.4 2.2 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Sec20 PF03908.8 EMG45486.1 - 2.3 7.9 11.0 0.58 9.8 0.2 4.2 3 1 0 4 4 4 0 Sec20 IncA PF04156.9 EMG45486.1 - 4.6 6.8 6.4 26 4.3 0.1 2.9 1 1 1 2 2 2 0 IncA protein Chs3p PF12271.3 EMG45487.1 - 1.8e-129 430.9 25.4 2e-129 430.7 17.6 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF2404 PF10296.4 EMG45488.1 - 2.6e-07 30.6 5.7 2.9e-07 30.5 0.0 3.4 3 1 1 4 4 4 1 Putative integral membrane protein conserved region (DUF2404) Ndr PF03096.9 EMG45488.1 - 0.0069 14.9 0.5 0.015 13.8 0.4 1.5 1 0 0 1 1 1 1 Ndr family DUF2782 PF11191.3 EMG45488.1 - 0.16 11.9 1.3 0.27 11.2 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) Peptidase_C12 PF01088.16 EMG45489.1 - 3.6e-53 179.9 0.0 4e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Peptidase_C39 PF03412.10 EMG45489.1 - 0.067 12.9 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase C39 family eIF-4B PF06273.6 EMG45490.1 - 9.9 4.7 7.7 0.9 8.2 1.4 1.8 2 0 0 2 2 2 0 Plant specific eukaryotic initiation factor 4B PRA1 PF03208.14 EMG45492.1 - 3.3e-43 146.6 0.7 3.9e-43 146.4 0.5 1.1 1 0 0 1 1 1 1 PRA1 family protein Cation_ATPase_C PF00689.16 EMG45492.1 - 0.17 11.4 3.8 0.91 9.0 1.4 2.2 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus ABC2_membrane_4 PF12730.2 EMG45492.1 - 0.93 8.6 13.5 1.2 8.1 9.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein PsbI PF02532.9 EMG45492.1 - 1.7 8.3 4.9 4 7.1 3.4 1.7 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Ribosomal_S8 PF00410.14 EMG45493.1 - 1.3e-25 89.7 0.0 1.8e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S11 PF00411.14 EMG45494.1 - 5.6e-40 135.9 0.7 6.6e-40 135.7 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 DUF3445 PF11927.3 EMG45496.1 - 9.9e-75 251.1 0.2 1.3e-74 250.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Sel1 PF08238.7 EMG45497.1 - 3e-07 30.8 0.1 0.00015 22.2 0.1 3.3 3 0 0 3 3 3 1 Sel1 repeat UCH PF00443.24 EMG45499.1 - 8.1e-81 271.0 0.0 2.6e-80 269.3 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMG45499.1 - 1.3e-17 64.2 0.4 6.2e-09 35.7 0.0 2.8 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EMG45499.1 - 0.0015 18.9 0.1 0.0015 18.9 0.1 2.9 3 0 0 3 3 3 1 DUSP domain Nucleoplasmin PF03066.10 EMG45499.1 - 6.8 6.1 19.6 1.1 8.7 10.2 2.1 2 0 0 2 2 2 0 Nucleoplasmin Beach PF02138.13 EMG45500.1 - 1.1e-107 359.5 1.3 1.1e-107 359.5 0.9 3.1 3 0 0 3 3 3 1 Beige/BEACH domain PH_BEACH PF14844.1 EMG45500.1 - 6.2e-12 45.2 0.0 2.2e-11 43.5 0.0 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EMG45500.1 - 0.026 14.4 0.9 1.7 8.6 0.1 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat MFS_1 PF07690.11 EMG45501.1 - 6.1e-31 107.4 43.5 1.5e-20 73.2 11.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG45501.1 - 8.1e-06 24.6 18.3 8.1e-06 24.6 12.7 3.0 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 EMG45501.1 - 0.02 14.6 4.1 0.037 13.8 0.3 2.8 2 0 0 2 2 2 0 MFS_1 like family DUF2012 PF09430.5 EMG45502.1 - 2.3e-05 24.2 0.3 5.1e-05 23.1 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2012) Cna_B PF05738.8 EMG45502.1 - 0.013 15.2 1.1 0.013 15.2 0.7 2.1 2 0 0 2 2 2 0 Cna protein B-type domain Y_Y_Y PF07495.8 EMG45502.1 - 0.017 14.9 0.5 0.071 12.8 0.2 2.2 2 0 0 2 2 2 0 Y_Y_Y domain Med26 PF08711.6 EMG45503.1 - 1.8e-12 46.5 0.1 3.4e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Ribosom_S12_S23 PF00164.20 EMG45504.1 - 2e-40 137.0 0.3 2.4e-40 136.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Mito_carr PF00153.22 EMG45505.1 - 5.3e-52 173.5 0.0 8e-19 67.1 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein LisH PF08513.6 EMG45506.1 - 0.0017 18.0 0.0 0.004 16.8 0.0 1.6 1 0 0 1 1 1 1 LisH Glu_synthase PF01645.12 EMG45507.1 - 1e-155 518.2 0.1 5.9e-155 515.7 0.0 2.1 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EMG45507.1 - 5.2e-141 469.5 0.0 7.7e-141 468.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EMG45507.1 - 3.6e-115 384.1 0.1 1.7e-114 381.9 0.1 2.0 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.14 EMG45507.1 - 2.2e-64 216.2 2.8 3.8e-64 215.4 1.9 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EMG45507.1 - 1.6e-22 79.2 0.1 3.8e-22 77.9 0.1 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EMG45507.1 - 3.3e-16 59.7 0.0 2.4e-15 56.9 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMG45507.1 - 3.4e-11 43.5 0.1 1.6e-05 25.0 0.0 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMG45507.1 - 3.2e-10 40.2 0.0 1e-06 29.0 0.0 3.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMG45507.1 - 6.5e-09 35.6 0.0 2.5e-08 33.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EMG45507.1 - 6.5e-07 28.7 0.0 1.1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EMG45507.1 - 1.5e-05 24.0 0.1 3.7e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMG45507.1 - 3.5e-05 22.4 0.1 3.5e-05 22.4 0.1 2.1 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.19 EMG45507.1 - 0.00012 21.0 0.1 0.00025 20.0 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EMG45507.1 - 0.00014 21.0 0.3 0.0024 16.9 0.0 2.7 3 0 0 3 3 3 1 Thi4 family FAD_oxidored PF12831.2 EMG45507.1 - 0.00069 18.8 0.1 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 EMG45507.1 - 0.00084 19.0 0.0 0.0023 17.6 0.0 1.8 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 EMG45507.1 - 0.0011 18.1 0.0 0.0025 16.9 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 EMG45507.1 - 0.0013 18.9 1.1 0.25 11.6 0.0 2.9 2 0 0 2 2 2 1 Putative NAD(P)-binding GIDA PF01134.17 EMG45507.1 - 0.003 16.4 0.7 0.01 14.7 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EMG45507.1 - 0.0036 16.8 0.0 0.023 14.2 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EMG45507.1 - 0.0061 15.7 0.1 0.11 11.6 0.0 2.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EMG45507.1 - 0.009 16.1 0.0 5.1 7.2 0.0 2.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DJ-1_PfpI PF01965.19 EMG45507.1 - 0.032 13.6 0.1 0.24 10.8 0.0 2.3 1 1 1 2 2 2 0 DJ-1/PfpI family NAD_binding_10 PF13460.1 EMG45507.1 - 0.07 13.1 0.1 2.1 8.3 0.0 2.7 2 1 0 2 2 2 0 NADH(P)-binding AdoHcyase_NAD PF00670.16 EMG45507.1 - 0.078 12.8 0.6 9.8 5.9 0.0 3.0 3 0 0 3 3 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FMO-like PF00743.14 EMG45507.1 - 0.16 10.0 0.0 2.6 6.1 0.0 2.3 1 1 1 2 2 2 0 Flavin-binding monooxygenase-like RNase_PH PF01138.16 EMG45508.1 - 1.1e-10 41.9 0.0 3.4e-10 40.3 0.0 1.8 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EMG45508.1 - 0.04 13.8 0.1 0.088 12.7 0.1 1.6 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 CAP PF00188.21 EMG45509.1 - 5.9e-19 68.7 2.1 5.9e-19 68.7 1.5 1.9 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Macoilin PF09726.4 EMG45509.1 - 5.1 5.2 9.7 6.1 5.0 6.8 1.1 1 0 0 1 1 1 0 Transmembrane protein K_trans PF02705.11 EMG45511.1 - 3e-170 567.1 19.5 3.9e-170 566.7 13.5 1.1 1 0 0 1 1 1 1 K+ potassium transporter gpUL132 PF11359.3 EMG45511.1 - 0.24 10.7 1.3 0.45 9.8 0.0 2.1 2 0 0 2 2 2 0 Glycoprotein UL132 LSM14 PF12701.2 EMG45512.1 - 8.1e-29 99.2 0.0 1.9e-28 98.0 0.0 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EMG45512.1 - 1.3e-08 35.3 13.0 4.8e-07 30.2 1.2 3.5 2 2 1 3 3 3 2 FDF domain SM-ATX PF14438.1 EMG45512.1 - 0.00017 21.4 0.0 0.00044 20.1 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain TFIIA PF03153.8 EMG45512.1 - 0.25 11.1 20.4 0.32 10.8 14.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 EMG45512.1 - 0.44 9.8 29.0 0.64 9.3 20.1 1.3 1 0 0 1 1 1 0 Vta1 like GRP PF07172.6 EMG45512.1 - 0.56 10.7 10.3 1.6 9.2 7.1 1.7 1 0 0 1 1 1 0 Glycine rich protein family LRR_4 PF12799.2 EMG45513.1 - 3.9e-27 93.3 40.5 1.6e-05 24.3 2.0 10.3 6 3 4 10 10 10 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG45513.1 - 5.2e-20 70.9 41.6 3.7e-05 23.3 0.6 9.1 3 2 7 11 11 11 10 Leucine rich repeat LRR_1 PF00560.28 EMG45513.1 - 1.8e-09 36.2 47.3 0.47 10.6 0.0 14.8 14 3 2 16 16 16 3 Leucine Rich Repeat LRR_7 PF13504.1 EMG45513.1 - 3.4e-09 35.4 31.1 3.3 8.3 0.0 14.3 16 0 0 16 16 16 1 Leucine rich repeat LRR_6 PF13516.1 EMG45513.1 - 0.0022 17.8 47.4 1.5 9.0 0.0 13.9 14 2 1 15 15 15 3 Leucine Rich repeat FNIP PF05725.7 EMG45513.1 - 0.2 11.6 30.1 0.99 9.4 0.4 8.3 6 4 3 9 9 9 0 FNIP Repeat GTP_EFTU PF00009.22 EMG45514.1 - 4.8e-62 208.7 0.3 6.2e-61 205.1 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EMG45514.1 - 2.8e-25 87.9 0.1 5.6e-25 86.9 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EMG45514.1 - 3.4e-16 58.8 0.1 8.3e-10 38.4 0.0 2.8 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EMG45514.1 - 2.9e-09 36.9 0.0 8.5e-09 35.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMG45514.1 - 0.00015 21.7 0.6 0.00059 19.7 0.1 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EMG45514.1 - 0.013 16.0 0.0 0.046 14.2 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein SH3_1 PF00018.23 EMG45515.1 - 3.1e-08 32.8 0.6 7.3e-08 31.6 0.4 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMG45515.1 - 0.001 18.5 0.1 0.002 17.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EMG45515.1 - 0.0049 16.4 0.3 0.012 15.2 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain Transglut_core PF01841.14 EMG45515.1 - 0.054 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily PI3_PI4_kinase PF00454.22 EMG45516.1 - 3e-43 147.9 0.0 7.6e-43 146.6 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EMG45516.1 - 1e-32 112.8 7.2 9.5e-21 73.7 0.4 2.9 3 0 0 3 3 3 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.19 EMG45516.1 - 8.3e-28 96.9 1.9 1e-27 96.6 0.1 2.1 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 His_Phos_1 PF00300.17 EMG45517.1 - 2e-12 47.4 0.0 3.6e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1415 PF07209.7 EMG45517.1 - 0.048 13.4 0.2 1.1 8.9 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1415) IFRD PF05004.8 EMG45518.1 - 1e-14 54.3 0.1 1e-14 54.3 0.1 3.7 4 1 1 5 5 5 1 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.1 EMG45518.1 - 0.019 15.4 0.2 0.06 13.8 0.2 1.9 1 0 0 1 1 1 0 HEAT-like repeat Acetyltransf_1 PF00583.19 EMG45519.1 - 5.8e-08 32.6 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EMG45519.1 - 1.7e-06 27.7 0.0 2.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EMG45519.1 - 0.027 14.5 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMG45519.1 - 0.032 14.1 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMG45519.1 - 0.036 14.2 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3639 PF12341.3 EMG45520.1 - 2.2e-05 24.3 1.4 0.00013 21.8 0.9 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3639) RAB3GAP2_N PF14655.1 EMG45520.1 - 0.00076 18.5 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus CNH PF00780.17 EMG45520.1 - 0.0041 16.5 0.0 0.11 11.9 0.0 2.4 1 1 0 2 2 2 1 CNH domain Daxx PF03344.10 EMG45520.1 - 0.018 13.5 5.2 0.029 12.8 3.6 1.2 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EMG45520.1 - 0.1 10.6 6.6 0.15 10.0 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 EMG45520.1 - 0.82 8.3 15.6 1.5 7.5 10.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) AAA_11 PF13086.1 EMG45521.1 - 2.4e-58 197.4 0.7 2.4e-58 197.4 0.5 1.8 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EMG45521.1 - 4.8e-58 195.8 1.7 1.8e-57 193.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain DUF1748 PF08520.5 EMG45521.1 - 3.5e-26 90.6 0.1 9.8e-26 89.2 0.1 1.9 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) AAA_19 PF13245.1 EMG45521.1 - 5.5e-12 45.2 0.0 3.5e-11 42.6 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EMG45521.1 - 5.3e-10 39.1 0.0 1.3e-07 31.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.13 EMG45521.1 - 2e-09 37.3 0.1 0.0014 18.2 0.0 4.0 3 1 1 4 4 4 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EMG45521.1 - 9.3e-09 35.3 0.4 9.3e-09 35.3 0.3 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EMG45521.1 - 8.5e-05 21.6 0.1 0.0073 15.3 0.0 2.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EMG45521.1 - 0.0001 22.4 0.7 0.0022 18.1 0.5 2.7 1 1 0 1 1 1 1 AAA domain PIF1 PF05970.9 EMG45521.1 - 0.00014 20.9 1.0 0.011 14.7 0.0 3.0 3 0 0 3 3 3 1 PIF1-like helicase PhoH PF02562.11 EMG45521.1 - 0.00017 20.8 0.2 0.0022 17.2 0.1 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_16 PF13191.1 EMG45521.1 - 0.00042 20.3 0.1 0.001 19.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Zot PF05707.7 EMG45521.1 - 0.00044 19.7 0.8 0.0011 18.5 0.0 2.1 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.12 EMG45521.1 - 0.0017 17.8 0.2 0.012 15.0 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.24 EMG45521.1 - 0.0021 18.2 0.2 0.0075 16.4 0.2 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Helicase_RecD PF05127.9 EMG45521.1 - 0.0023 17.5 0.0 0.011 15.4 0.0 2.3 2 1 0 2 2 1 1 Helicase T2SE PF00437.15 EMG45521.1 - 0.0029 16.5 0.1 0.0053 15.7 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 EMG45521.1 - 0.013 15.3 4.8 0.12 12.2 0.1 3.4 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 EMG45521.1 - 0.017 15.4 1.7 0.07 13.4 1.2 2.2 1 1 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 EMG45521.1 - 0.025 14.2 4.0 0.046 13.4 0.7 2.9 3 1 0 3 3 2 0 Archaeal ATPase AAA_25 PF13481.1 EMG45521.1 - 0.031 13.6 0.0 0.079 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.1 EMG45521.1 - 0.046 13.8 0.0 0.22 11.6 0.0 2.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_33 PF13671.1 EMG45521.1 - 0.065 13.1 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EMG45521.1 - 0.072 13.9 2.1 0.34 11.7 0.7 2.8 2 1 0 2 2 1 0 AAA domain Siah-Interact_N PF09032.6 EMG45521.1 - 0.11 12.5 4.3 0.29 11.2 3.0 1.7 1 0 0 1 1 1 0 Siah interacting protein, N terminal TK PF00265.13 EMG45521.1 - 1.8 8.1 5.5 3.2 7.2 0.0 3.2 3 0 0 3 3 3 0 Thymidine kinase AAA_18 PF13238.1 EMG45521.1 - 2.6 8.3 7.7 7.8 6.8 3.4 3.1 3 1 0 3 3 2 0 AAA domain CAP PF00188.21 EMG45522.1 - 5.3e-13 49.5 4.8 2e-12 47.6 3.3 1.8 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Trypan_PARP PF05887.6 EMG45522.1 - 7e-08 32.3 113.9 1.5e+04 -25.0 79.0 3.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PseudoU_synth_2 PF00849.17 EMG45523.1 - 3.4e-23 82.2 0.0 5.2e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase EIF_2_alpha PF07541.7 EMG45524.1 - 4e-39 132.8 0.2 1e-38 131.5 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EMG45524.1 - 1.6e-14 53.7 1.2 3e-14 52.8 0.8 1.5 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.4 EMG45524.1 - 0.088 12.7 0.3 0.2 11.6 0.2 1.7 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 LRR_4 PF12799.2 EMG45525.1 - 4.2e-20 70.9 41.4 0.00012 21.6 1.3 9.2 5 1 6 11 11 11 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG45525.1 - 6.1e-14 51.5 26.2 0.0013 18.4 0.5 8.2 4 3 4 9 9 9 7 Leucine rich repeat FNIP PF05725.7 EMG45525.1 - 2.2e-11 43.5 21.4 0.0007 19.5 1.1 7.8 5 3 4 9 9 9 5 FNIP Repeat LRR_7 PF13504.1 EMG45525.1 - 4.4e-09 35.0 26.2 3.4 8.2 0.0 12.2 14 1 1 15 15 15 4 Leucine rich repeat LRR_1 PF00560.28 EMG45525.1 - 1.3e-08 33.6 29.4 1.3 9.3 0.2 11.3 11 2 2 13 13 13 5 Leucine Rich Repeat LRR_6 PF13516.1 EMG45525.1 - 0.00069 19.4 27.4 5.4 7.4 0.3 10.9 14 0 0 14 14 14 1 Leucine Rich repeat MFS_1 PF07690.11 EMG45526.1 - 1.5e-27 96.2 79.0 9.9e-20 70.5 34.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMG45526.1 - 5.7e-07 28.2 39.3 0.00021 19.8 10.6 2.7 1 1 2 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.2 EMG45526.1 - 0.037 13.8 0.0 0.037 13.8 0.0 3.4 4 2 0 4 4 4 0 MFS_1 like family FixP_N PF14715.1 EMG45526.1 - 0.25 10.7 3.0 1.5 8.3 2.1 2.4 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP WD40 PF00400.27 EMG45527.1 - 3.2e-20 71.1 4.2 4.8e-05 23.0 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat SRA1 PF07304.6 EMG45527.1 - 0.00046 19.9 2.8 0.00046 19.9 1.9 2.9 2 1 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Glyco_hydro_65m PF03632.10 EMG45528.1 - 8.7e-85 284.6 2.3 3e-84 282.8 0.6 2.3 2 1 0 2 2 2 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 EMG45528.1 - 2.3e-30 105.7 0.2 4.3e-30 104.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain F5_F8_type_C PF00754.20 EMG45528.1 - 0.0006 19.6 1.1 0.0019 18.0 0.8 1.9 1 0 0 1 1 1 1 F5/8 type C domain Glyco_hyd_65N_2 PF14498.1 EMG45528.1 - 0.037 13.6 0.0 0.095 12.3 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 65, N-terminal domain DUF2152 PF10222.4 EMG45528.1 - 0.14 10.3 0.8 0.42 8.7 0.1 2.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2152) SPO22 PF08631.5 EMG45529.1 - 6.8e-50 169.6 4.5 6.8e-50 169.6 3.1 3.4 3 1 1 4 4 4 1 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.1 EMG45529.1 - 0.00015 22.0 0.1 0.092 13.0 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 EMG45529.1 - 0.0079 16.3 8.9 0.41 10.8 0.3 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EMG45529.1 - 0.0096 15.5 11.1 0.18 11.4 0.3 4.0 3 1 1 4 4 4 3 TPR repeat TPR_2 PF07719.12 EMG45529.1 - 0.014 15.2 3.4 0.33 10.9 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMG45529.1 - 0.046 13.6 6.7 0.86 9.5 0.2 3.7 2 1 2 4 4 4 0 Tetratricopeptide repeat Ribosomal_L34e PF01199.13 EMG45530.1 - 2.4e-35 120.5 6.5 2.4e-35 120.5 4.5 1.5 2 0 0 2 2 2 1 Ribosomal protein L34e DUF3133 PF11331.3 EMG45530.1 - 0.018 14.6 1.1 0.057 12.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) Zn_ribbon_recom PF13408.1 EMG45530.1 - 0.02 15.1 2.4 0.05 13.8 1.7 1.7 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain DUF1428 PF07237.6 EMG45530.1 - 0.049 13.5 0.1 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) Cytochrome_C7 PF14522.1 EMG45530.1 - 0.059 13.0 0.7 0.1 12.2 0.5 1.5 1 1 0 1 1 1 0 Cytochrome c7 Ribosomal_S27e PF01667.12 EMG45530.1 - 0.091 12.3 0.9 0.79 9.3 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 GFA PF04828.9 EMG45530.1 - 0.2 11.6 1.2 0.62 10.0 0.8 2.0 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_5 PF13719.1 EMG45530.1 - 6.4 6.4 6.2 2.5 7.7 0.3 2.5 2 1 0 2 2 2 0 zinc-ribbon domain Ribonuc_L-PSP PF01042.16 EMG45531.1 - 1.4e-39 134.6 0.2 1.7e-39 134.3 0.1 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF2254 PF10011.4 EMG45533.1 - 0.41 9.0 1.9 3 6.2 0.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) Daxx PF03344.10 EMG45534.1 - 0.31 9.4 9.2 0.35 9.3 6.4 1.1 1 0 0 1 1 1 0 Daxx Family Cytomega_TRL10 PF06084.6 EMG45534.1 - 0.58 9.9 5.4 3.2 7.5 1.0 2.2 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein COQ7 PF03232.8 EMG45535.1 - 0.096 12.1 1.1 0.22 10.9 0.7 1.5 1 1 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Cyclin PF08613.6 EMG45536.1 - 1.9e-32 112.7 12.3 1.9e-32 112.7 8.5 4.0 2 2 0 2 2 2 1 Cyclin SDA1 PF05285.7 EMG45536.1 - 0.00063 19.1 14.8 0.0011 18.2 10.2 1.4 1 0 0 1 1 1 1 SDA1 NOA36 PF06524.7 EMG45536.1 - 0.004 16.4 12.8 0.0068 15.7 8.9 1.3 1 0 0 1 1 1 1 NOA36 protein Nop25 PF09805.4 EMG45536.1 - 1.5 8.9 20.7 0.21 11.6 10.9 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Nop14 PF04147.7 EMG45536.1 - 1.8 6.3 32.8 4.1 5.1 22.8 1.5 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 EMG45536.1 - 3.1 7.4 26.9 0.14 11.8 14.1 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Prothymosin PF03247.9 EMG45536.1 - 5.2 7.2 39.9 0.77 9.9 21.7 2.5 2 0 0 2 2 2 0 Prothymosin/parathymosin family RTA1 PF04479.8 EMG45537.1 - 1.7e-50 171.6 11.4 2.5e-50 171.0 7.9 1.3 1 0 0 1 1 1 1 RTA1 like protein Phage_holin_6 PF10746.4 EMG45537.1 - 2.1 8.1 4.9 1.5 8.5 0.7 2.3 2 0 0 2 2 2 0 Phage holin family 6 DUF1995 PF09353.5 EMG45538.1 - 0.025 14.1 0.2 0.88 9.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1995) DGCR6 PF07324.6 EMG45539.1 - 0.62 9.5 4.7 0.13 11.7 0.1 1.8 2 0 0 2 2 2 0 DiGeorge syndrome critical region 6 (DGCR6) protein Pkinase PF00069.20 EMG45540.1 - 3.7e-63 213.1 0.0 5.5e-63 212.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG45540.1 - 1.8e-24 86.2 0.0 2.8e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMG45540.1 - 0.025 14.3 0.0 0.056 13.1 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EMG45540.1 - 0.16 11.0 0.1 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L11_N PF03946.9 EMG45541.1 - 4.1e-26 90.2 0.5 7.2e-26 89.4 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EMG45541.1 - 3.5e-20 71.8 1.0 5.2e-20 71.3 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain RAI1 PF08652.6 EMG45542.1 - 2.3e-28 97.7 0.3 5.2e-28 96.6 0.2 1.7 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Catalase PF00199.14 EMG45543.1 - 5e-50 170.2 0.1 5.5e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Catalase LRR_4 PF12799.2 EMG45544.1 - 2.1e-07 30.3 18.6 4.2e-05 23.0 0.1 6.8 5 2 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG45544.1 - 0.00047 19.8 15.9 0.087 12.5 0.2 6.1 5 1 1 6 6 6 2 Leucine rich repeat LRR_1 PF00560.28 EMG45544.1 - 0.0039 16.9 5.0 0.99 9.6 0.0 6.5 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_7 PF13504.1 EMG45544.1 - 0.0094 15.9 9.1 4 8.0 0.2 7.3 8 0 0 8 8 8 1 Leucine rich repeat LRR_6 PF13516.1 EMG45544.1 - 1.6 9.0 11.7 2.9 8.2 0.3 5.6 5 0 0 5 5 5 0 Leucine Rich repeat adh_short PF00106.20 EMG45545.1 - 2.5e-16 60.0 0.0 3.9e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMG45545.1 - 1.3e-11 44.5 0.0 2e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMG45545.1 - 1.7e-06 28.0 0.0 1.5e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMG45545.1 - 0.0019 17.6 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMG45545.1 - 0.019 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding RmlD_sub_bind PF04321.12 EMG45545.1 - 0.026 13.4 0.3 0.13 11.0 0.0 2.3 3 0 0 3 3 3 0 RmlD substrate binding domain LMBR1 PF04791.11 EMG45545.1 - 9 4.7 10.1 16 3.8 7.0 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein Ras PF00071.17 EMG45546.1 - 6.7e-56 188.1 0.0 8.2e-56 187.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMG45546.1 - 3.1e-12 47.0 0.0 4.7e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMG45546.1 - 1.4e-08 34.1 0.0 1.8e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family CbiA PF01656.18 EMG45546.1 - 0.14 11.5 0.7 6.4 6.1 0.0 2.2 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain RRM_1 PF00076.17 EMG45547.1 - 4.7e-08 32.5 0.1 1.5e-07 30.9 0.1 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG45547.1 - 8.9e-08 32.0 0.1 2.2e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpc4 PF05132.9 EMG45547.1 - 1.5 8.8 11.5 0.36 10.7 3.1 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 Endonuc_Holl PF10107.4 EMG45547.1 - 7.2 6.2 9.8 4.6 6.9 2.0 2.2 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase PRCC PF10253.4 EMG45548.1 - 0.033 14.8 1.5 0.04 14.6 1.0 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting LTD PF00932.14 EMG45548.1 - 0.18 11.8 0.9 0.34 11.0 0.6 1.5 1 1 0 1 1 1 0 Lamin Tail Domain WD40 PF00400.27 EMG45549.1 - 5.5e-09 35.5 3.2 0.004 16.9 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat IncA PF04156.9 EMG45549.1 - 1.2 8.7 4.0 1.7 8.1 2.7 1.3 1 0 0 1 1 1 0 IncA protein Cor1 PF04803.7 EMG45550.1 - 0.14 11.9 8.0 0.022 14.4 2.6 1.8 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region PMC2NT PF08066.7 EMG45550.1 - 1.4 9.2 7.2 0.25 11.6 0.4 3.1 3 2 2 5 5 5 0 PMC2NT (NUC016) domain Fungal_trans PF04082.13 EMG45552.1 - 8.5e-19 67.4 1.1 2e-18 66.1 0.1 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG45552.1 - 2.2e-06 27.4 9.8 3.5e-06 26.8 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BT1 PF03092.11 EMG45552.1 - 0.0032 16.2 0.0 0.0065 15.2 0.0 1.4 1 0 0 1 1 1 1 BT1 family CCDC92 PF14916.1 EMG45552.1 - 0.0039 16.7 0.2 0.0039 16.7 0.1 2.7 2 0 0 2 2 2 1 Coiled-coil domain of unknown function PAT1 PF09770.4 EMG45553.1 - 0.00012 20.5 72.1 0.00014 20.2 50.0 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF3452 PF11934.3 EMG45553.1 - 2.7 7.2 9.9 8.5 5.7 5.8 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) NAGidase PF07555.8 EMG45553.1 - 2.8 6.7 13.0 0.33 9.8 5.6 1.8 1 1 1 2 2 2 0 beta-N-acetylglucosaminidase Mem_trans PF03547.13 EMG45553.1 - 3.4 5.8 5.3 3.5 5.8 3.7 1.3 1 0 0 1 1 1 0 Membrane transport protein TFIIA PF03153.8 EMG45553.1 - 5.2 6.8 46.1 7.7 6.2 32.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.20 EMG45554.1 - 9.2e-67 224.9 0.0 1.1e-66 224.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG45554.1 - 2.5e-30 105.4 0.0 3.3e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG45554.1 - 0.00036 19.5 0.0 0.00059 18.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMG45554.1 - 0.02 14.6 0.1 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DAO PF01266.19 EMG45555.1 - 7.8e-54 182.9 0.0 8.8e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMG45555.1 - 1.1e-07 31.8 0.0 2.3e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMG45555.1 - 8.1e-05 22.7 0.1 0.0026 17.8 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EMG45555.1 - 0.00078 19.4 0.1 0.0023 17.9 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox_2 PF07992.9 EMG45555.1 - 0.0032 17.3 0.1 0.026 14.3 0.0 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMG45555.1 - 0.0077 16.6 0.3 0.017 15.5 0.1 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMG45555.1 - 0.012 14.5 0.1 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.11 EMG45555.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 EMG45555.1 - 0.019 13.8 0.1 0.035 12.9 0.0 1.4 2 0 0 2 2 2 0 FAD binding domain GDI PF00996.13 EMG45555.1 - 0.025 12.9 0.1 0.035 12.4 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor FAD_binding_3 PF01494.14 EMG45555.1 - 0.063 12.3 0.1 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 EMG45555.1 - 0.065 12.8 0.7 0.17 11.5 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EMG45555.1 - 0.13 10.7 0.1 0.19 10.1 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein DUF3895 PF13034.1 EMG45555.1 - 0.13 11.7 0.1 2.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3895) NAD_binding_9 PF13454.1 EMG45555.1 - 0.18 11.6 0.1 0.34 10.6 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Adaptin_N PF01602.15 EMG45557.1 - 9.1e-77 258.5 18.5 1.3e-76 258.0 12.8 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EMG45557.1 - 1.3e-13 51.2 1.4 4e-13 49.6 1.0 1.9 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT PF02985.17 EMG45557.1 - 4.5e-05 23.1 0.3 0.12 12.5 0.0 3.1 2 0 0 2 2 2 2 HEAT repeat Alpha_adaptin_C PF02296.11 EMG45557.1 - 0.00035 20.5 0.0 0.0015 18.4 0.0 2.1 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Vac14_Fab1_bd PF12755.2 EMG45557.1 - 0.0022 18.3 1.6 0.0064 16.8 0.1 2.5 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 EMG45557.1 - 0.0059 16.8 0.5 0.046 14.0 0.3 2.5 2 1 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.1 EMG45557.1 - 0.23 12.0 0.2 43 4.7 0.1 2.8 2 0 0 2 2 2 0 HEAT-like repeat SH3_9 PF14604.1 EMG45558.1 - 1.9e-09 36.9 1.4 4.3e-09 35.7 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EMG45558.1 - 9.5e-09 34.5 0.1 1.8e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMG45558.1 - 7.5e-06 25.3 0.0 1.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain CAP PF00188.21 EMG45559.1 - 5.3e-17 62.4 4.8 5.3e-17 62.4 3.4 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Anoctamin PF04547.7 EMG45560.1 - 1.1e-89 301.2 15.5 1.5e-89 300.7 10.7 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel La PF05383.12 EMG45561.1 - 1.3e-20 72.9 0.6 3e-20 71.7 0.1 1.9 2 0 0 2 2 2 1 La domain DUF2634 PF10934.3 EMG45561.1 - 0.03 14.1 0.3 0.18 11.5 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2634) MHCassoc_trimer PF08831.5 EMG45561.1 - 0.036 13.9 0.9 0.13 12.1 0.1 2.3 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain Ala_racemase_N PF01168.15 EMG45562.1 - 9.2e-44 149.5 0.0 1e-43 149.4 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DHQS PF01959.11 EMG45562.1 - 0.0031 16.2 0.2 0.061 12.0 0.0 2.1 2 0 0 2 2 2 1 3-dehydroquinate synthase (EC 4.6.1.3) SCO1-SenC PF02630.9 EMG45562.1 - 0.022 14.3 0.7 0.036 13.7 0.5 1.3 1 0 0 1 1 1 0 SCO1/SenC TMF_TATA_bd PF12325.3 EMG45562.1 - 0.075 12.7 2.3 0.092 12.4 0.3 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3240 PF11582.3 EMG45562.1 - 0.13 12.1 0.3 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3240) TFIIA PF03153.8 EMG45564.1 - 0.98 9.2 11.2 1.2 9.0 7.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EMG45564.1 - 2 6.5 18.9 2.1 6.4 13.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CLASP_N PF12348.3 EMG45565.1 - 8.6e-84 280.4 10.0 1.3e-79 266.7 1.3 3.1 3 0 0 3 3 3 2 CLASP N terminal YtzH PF14165.1 EMG45565.1 - 0.037 14.2 0.7 8.3 6.7 0.1 3.6 3 0 0 3 3 3 0 YtzH-like protein Peptidase_C13 PF01650.13 EMG45566.1 - 3.5e-46 157.5 1.1 5.9e-46 156.8 0.2 1.7 2 0 0 2 2 2 1 Peptidase C13 family ResIII PF04851.10 EMG45566.1 - 4.7e-23 81.9 0.2 1.4e-22 80.4 0.1 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EMG45566.1 - 3e-14 52.6 0.1 8.1e-14 51.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMG45566.1 - 2e-13 50.2 0.5 5.8e-13 48.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 EMG45566.1 - 0.0025 16.8 0.1 0.0049 15.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.9 EMG45566.1 - 0.0042 16.8 0.2 0.0088 15.8 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_11 PF13086.1 EMG45566.1 - 0.009 15.6 0.3 0.084 12.4 0.0 2.3 1 1 1 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 EMG45566.1 - 0.011 14.3 0.0 0.019 13.6 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Helicase_C_2 PF13307.1 EMG45566.1 - 0.042 13.8 0.2 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 Helicase C-terminal domain Pol_alpha_B_N PF08418.5 EMG45567.1 - 2.3e-51 174.8 10.0 3.5e-51 174.1 6.9 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 EMG45567.1 - 1.5e-34 119.0 0.1 2.5e-34 118.3 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CHDCT2 PF08074.6 EMG45567.1 - 0.063 13.0 0.3 0.18 11.5 0.2 1.7 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Pkinase PF00069.20 EMG45568.1 - 4.9e-71 238.9 0.3 6.8e-71 238.4 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG45568.1 - 1e-31 109.9 0.2 8.2e-31 107.0 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG45568.1 - 0.00019 20.5 0.2 0.16 10.9 0.0 2.9 3 0 0 3 3 3 2 Kinase-like STE PF02200.11 EMG45569.1 - 9.7e-33 112.6 1.1 3.6e-32 110.7 0.3 2.2 2 1 0 2 2 2 1 STE like transcription factor Glutaredoxin PF00462.19 EMG45570.1 - 1.3e-17 63.5 0.1 4.2e-17 61.8 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin MMR1 PF08505.5 EMG45571.1 - 0.028 14.4 2.1 0.051 13.6 1.5 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF3781 PF12636.2 EMG45572.1 - 0.047 13.6 0.1 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3781) Imm13 PF15564.1 EMG45572.1 - 0.18 11.5 4.0 0.16 11.6 1.4 1.9 1 1 1 2 2 2 0 Immunity protein 13 Mt_ATP-synt_D PF05873.7 EMG45573.1 - 1.4e-12 47.5 3.6 1.7e-12 47.2 2.5 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Kinesin-related PF06548.6 EMG45573.1 - 0.0022 16.6 2.6 0.0026 16.3 1.8 1.0 1 0 0 1 1 1 1 Kinesin-related Borrelia_lipo_2 PF06238.6 EMG45573.1 - 0.039 13.9 2.1 0.076 13.0 1.5 1.4 1 1 0 1 1 1 0 Borrelia burgdorferi BBR25 lipoprotein V_ATPase_I PF01496.14 EMG45573.1 - 0.048 11.5 5.0 0.056 11.2 3.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vps51 PF08700.6 EMG45573.1 - 0.13 12.1 3.6 5.2 6.9 0.0 2.4 1 1 1 2 2 2 0 Vps51/Vps67 Tropomyosin PF00261.15 EMG45573.1 - 0.16 11.0 8.4 0.41 9.6 5.8 1.6 1 1 0 1 1 1 0 Tropomyosin Skp1 PF01466.14 EMG45574.1 - 4.4e-36 122.7 1.2 1.7e-35 120.8 0.7 2.0 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EMG45574.1 - 1.8e-18 66.3 0.1 4.7e-18 65.0 0.1 1.7 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BUD22 PF09073.5 EMG45575.1 - 0.00078 18.6 22.8 0.00078 18.6 15.8 2.0 2 0 0 2 2 2 1 BUD22 CENP-T PF15511.1 EMG45575.1 - 0.0043 16.3 12.6 0.0066 15.7 8.7 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T SDA1 PF05285.7 EMG45575.1 - 5.9 6.0 33.3 12 5.0 23.1 1.5 1 0 0 1 1 1 0 SDA1 Thioredoxin_7 PF13899.1 EMG45576.1 - 2.9e-20 72.0 0.1 6e-20 71.0 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 EMG45576.1 - 3.2e-10 39.3 0.0 6.6e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain Thioredox_DsbH PF03190.10 EMG45576.1 - 0.00014 21.6 0.2 0.0003 20.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF255 SPT6_acidic PF14632.1 EMG45576.1 - 0.0064 16.6 8.3 0.0064 16.6 5.7 2.5 3 0 0 3 3 3 1 Acidic N-terminal SPT6 Nop53 PF07767.6 EMG45576.1 - 0.01 14.8 1.7 0.01 14.8 1.2 1.8 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Spt5_N PF11942.3 EMG45576.1 - 0.87 10.2 19.3 0.14 12.8 7.0 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.9 EMG45576.1 - 4.1 5.3 11.1 0.3 9.0 3.5 1.9 2 0 0 2 2 2 0 CDC45-like protein Pkinase PF00069.20 EMG45577.1 - 1.2e-53 181.9 0.0 1.9e-53 181.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG45577.1 - 1.9e-30 105.7 0.0 9e-30 103.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG45577.1 - 0.036 13.0 0.0 0.082 11.8 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EMG45577.1 - 0.048 13.3 0.1 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EMG45577.1 - 0.051 12.6 0.0 0.078 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PROL5-SMR PF15621.1 EMG45577.1 - 1.5 9.3 11.7 3.7 8.0 8.1 1.6 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family Peroxin-3 PF04882.7 EMG45578.1 - 3.8e-130 434.4 19.2 4.3e-130 434.2 13.3 1.0 1 0 0 1 1 1 1 Peroxin-3 Npa1 PF11707.3 EMG45579.1 - 9.1e-93 310.8 17.7 9.1e-93 310.8 12.3 3.9 4 1 1 5 5 5 1 Ribosome 60S biogenesis N-terminal GIDA PF01134.17 EMG45580.1 - 1.6e-151 504.6 0.0 2e-151 504.3 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EMG45580.1 - 5.6e-12 45.5 0.1 1.8e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 EMG45580.1 - 1.3e-05 25.2 0.2 3.1e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMG45580.1 - 0.021 13.9 0.6 0.038 13.0 0.4 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.19 EMG45580.1 - 0.025 13.5 0.6 1.4 7.7 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMG45580.1 - 0.12 11.1 0.7 0.22 10.3 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain CMS1 PF14617.1 EMG45581.1 - 1.1e-20 73.7 28.7 9.3e-18 64.1 19.9 2.9 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EMG45581.1 - 0.027 13.9 0.5 0.044 13.2 0.3 1.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase Vps51 PF08700.6 EMG45582.1 - 6.3e-15 54.7 0.6 6.3e-15 54.7 0.4 3.4 3 0 0 3 3 3 1 Vps51/Vps67 Zn_clus PF00172.13 EMG45583.1 - 1.2e-06 28.3 14.1 2.3e-06 27.4 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EMG45583.1 - 3.1 8.0 14.8 11 6.2 10.2 1.9 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region AA_permease PF00324.16 EMG45584.1 - 9.3e-30 103.3 7.9 1.1e-29 103.1 5.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG45584.1 - 5.8e-10 38.2 8.2 6.5e-10 38.1 5.7 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1113 PF06541.6 EMG45584.1 - 0.03 14.0 0.1 0.03 14.0 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1113) Presenilin PF01080.12 EMG45584.1 - 0.033 13.0 0.4 0.038 12.8 0.3 1.1 1 0 0 1 1 1 0 Presenilin AMP-binding PF00501.23 EMG45585.1 - 4.5e-61 206.4 0.0 3.6e-60 203.5 0.0 1.9 2 0 0 2 2 2 2 AMP-binding enzyme GATase_2 PF00310.16 EMG45586.1 - 5.7e-26 91.0 0.0 5e-20 71.5 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EMG45586.1 - 2.3e-15 56.6 0.0 4.8e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EMG45586.1 - 2.1e-12 46.8 0.0 3.7e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EMG45586.1 - 1.8e-10 40.6 0.0 3.4e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EMG45586.1 - 0.00021 20.1 0.0 0.0003 19.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRKCSH-like PF12999.2 EMG45586.1 - 0.036 13.6 0.0 0.099 12.2 0.0 1.8 1 0 0 1 1 1 0 Glucosidase II beta subunit-like DEAD PF00270.24 EMG45587.1 - 3.3e-41 140.5 0.0 4.8e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG45587.1 - 1.3e-24 85.8 0.0 2.4e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CBFB_NFYA PF02045.10 EMG45588.1 - 1.1e-29 102.7 7.9 2.2e-29 101.7 5.5 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Cse1 PF08506.5 EMG45589.1 - 1.3e-150 501.0 19.3 1.3e-150 501.0 13.4 2.0 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.10 EMG45589.1 - 4.2e-100 335.0 8.3 1e-99 333.8 5.8 1.7 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 EMG45589.1 - 2.3e-13 49.8 0.1 2.3e-13 49.8 0.1 4.0 4 0 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EMG45589.1 - 0.57 10.0 15.4 1.9 8.3 4.6 5.5 3 2 2 5 5 5 0 Exportin 1-like protein UAA PF08449.6 EMG45590.1 - 2.3e-15 56.3 24.4 2.8e-15 56.0 16.9 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EMG45590.1 - 8.7e-09 35.2 9.3 8.7e-09 35.2 6.5 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family PHO4 PF01384.15 EMG45590.1 - 0.0019 16.8 5.4 0.0019 16.8 3.7 2.6 1 1 0 2 2 2 1 Phosphate transporter family Tad PF13400.1 EMG45590.1 - 0.086 12.8 2.5 11 6.1 0.1 3.0 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Multi_Drug_Res PF00893.14 EMG45590.1 - 1.3 9.5 17.3 0.59 10.6 4.1 3.2 2 1 2 4 4 4 0 Small Multidrug Resistance protein LicD PF04991.8 EMG45591.1 - 4.3e-35 121.6 1.9 4.3e-35 121.6 1.4 3.4 3 2 0 3 3 3 1 LicD family MFS_1 PF07690.11 EMG45592.1 - 7.2e-39 133.4 60.3 5.1e-38 130.6 41.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG45592.1 - 7.9e-11 41.1 12.4 7.9e-11 41.1 8.6 4.0 3 1 0 4 4 4 1 Sugar (and other) transporter MFS_3 PF05977.8 EMG45592.1 - 2.7e-05 22.4 4.7 2.7e-05 22.4 3.3 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector YMF19 PF02326.10 EMG45592.1 - 0.015 15.8 0.3 0.015 15.8 0.2 3.9 4 1 0 4 4 4 0 Plant ATP synthase F0 DUF2457 PF10446.4 EMG45592.1 - 0.75 8.4 9.0 1.1 7.9 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Epimerase PF01370.16 EMG45593.1 - 4.1e-19 68.9 0.0 6.3e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMG45593.1 - 1.1e-12 47.4 0.0 3.4e-11 42.5 0.0 2.3 2 1 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 EMG45593.1 - 7.2e-12 44.5 0.0 1e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMG45593.1 - 4.9e-10 39.7 0.0 1.5e-09 38.1 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMG45593.1 - 3.6e-05 23.7 0.0 0.00026 20.9 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EMG45593.1 - 7e-05 21.8 0.0 0.00011 21.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EMG45593.1 - 0.00013 21.6 0.0 0.00031 20.4 0.0 1.6 2 0 0 2 2 2 1 KR domain NmrA PF05368.8 EMG45593.1 - 0.00034 19.9 0.0 0.016 14.4 0.0 2.3 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.12 EMG45593.1 - 0.0033 16.3 0.0 0.043 12.6 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain Semialdhyde_dh PF01118.19 EMG45593.1 - 0.011 15.9 0.0 0.15 12.3 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EMG45593.1 - 0.088 12.7 0.0 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DUF1479 PF07350.7 EMG45594.1 - 1.6e-140 468.2 0.0 1.9e-140 468.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) DnaJ PF00226.26 EMG45595.1 - 5e-11 42.1 0.0 1.1e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain LRR_4 PF12799.2 EMG45596.1 - 1.7e-08 33.9 15.3 4.7e-06 26.0 0.0 7.4 6 1 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG45596.1 - 1.6e-07 30.9 20.5 0.00016 21.3 0.0 7.3 6 1 3 9 9 9 3 Leucine rich repeat LRR_1 PF00560.28 EMG45596.1 - 8.2e-05 22.1 5.2 0.46 10.7 0.0 7.2 6 0 0 6 6 6 1 Leucine Rich Repeat FNIP PF05725.7 EMG45596.1 - 0.0037 17.1 23.5 0.2 11.6 0.0 9.4 7 4 2 9 9 9 1 FNIP Repeat LRR_6 PF13516.1 EMG45596.1 - 0.12 12.5 5.8 2.2 8.5 0.0 5.9 8 0 0 8 8 8 0 Leucine Rich repeat LRR_7 PF13504.1 EMG45596.1 - 5.2 7.7 15.2 19 6.0 0.0 8.1 10 1 0 10 10 10 0 Leucine rich repeat GCS PF03074.11 EMG45597.1 - 1.1e-136 455.8 1.3 2.6e-116 388.7 0.1 2.4 1 1 1 2 2 2 2 Glutamate-cysteine ligase PAP2 PF01569.16 EMG45598.1 - 3e-13 49.5 8.5 6.5e-13 48.4 5.9 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 EMG45598.1 - 0.012 15.8 7.0 0.012 15.8 4.8 2.3 2 0 0 2 2 2 0 PAP2 superfamily C-terminal GARS_A PF01071.14 EMG45599.1 - 3.6e-81 271.3 0.0 6.3e-81 270.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EMG45599.1 - 1.6e-35 121.5 0.7 2.8e-34 117.5 0.0 3.4 4 1 0 4 4 4 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EMG45599.1 - 1.3e-32 112.8 0.0 3e-32 111.7 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EMG45599.1 - 6e-24 84.0 0.1 1.3e-23 82.9 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EMG45599.1 - 2.1e-17 63.1 3.5 4.3e-17 62.1 1.2 2.6 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EMG45599.1 - 1.2e-08 34.8 0.0 5.4e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EMG45599.1 - 5.4e-08 31.9 0.0 1.1e-07 30.9 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EMG45599.1 - 9.8e-06 25.0 0.0 2.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EMG45599.1 - 6.9e-05 22.7 0.1 0.00047 20.0 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EMG45599.1 - 0.0038 16.5 0.1 0.0084 15.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 EMG45599.1 - 0.0092 15.4 0.7 0.023 14.1 0.0 2.0 3 0 0 3 3 3 1 RimK-like ATP-grasp domain Pkinase PF00069.20 EMG45600.1 - 1.7e-43 148.6 0.0 4.9e-43 147.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 EMG45600.1 - 8.6e-43 145.2 4.3 1.6e-42 144.4 2.6 1.8 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 EMG45600.1 - 2.4e-25 89.0 0.0 5.7e-25 87.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.1 EMG45600.1 - 1.2e-05 24.9 0.0 0.00069 19.1 0.0 2.8 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.16 EMG45600.1 - 0.00097 18.5 0.0 2.2 7.9 0.0 2.7 2 0 0 2 2 2 2 PQQ enzyme repeat Kdo PF06293.9 EMG45600.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sas10_Utp3 PF04000.10 EMG45601.1 - 1.1e-13 51.1 0.9 2.8e-13 49.8 0.6 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Auxin_canalis PF05703.6 EMG45601.1 - 0.0016 18.2 0.4 0.0016 18.2 0.3 1.4 1 1 0 1 1 1 1 Auxin canalisation Nop25 PF09805.4 EMG45602.1 - 4.7e-43 146.5 17.0 4.7e-43 146.5 11.8 2.2 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) zf-SAP30 PF13866.1 EMG45602.1 - 4.7 6.9 9.0 0.65 9.6 2.8 2.1 2 0 0 2 2 2 0 SAP30 zinc-finger EXS PF03124.9 EMG45603.1 - 2.1e-78 263.7 30.1 2.8e-78 263.3 20.9 1.1 1 0 0 1 1 1 1 EXS family Ribonuclease_3 PF00636.21 EMG45605.1 - 1.7e-09 38.1 0.2 1.6e-08 34.9 0.0 2.5 3 0 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EMG45605.1 - 2.7e-07 30.5 0.2 0.018 14.9 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.20 EMG45605.1 - 7.6e-07 29.6 0.0 1.9e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Swi5 PF07061.6 EMG45606.1 - 4.7e-23 80.7 3.0 7.2e-23 80.1 2.1 1.2 1 0 0 1 1 1 1 Swi5 DUF2408 PF10303.4 EMG45606.1 - 0.11 12.5 3.9 0.18 11.9 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF605 PF04652.11 EMG45606.1 - 1.3 8.3 10.7 1.5 8.1 7.4 1.1 1 0 0 1 1 1 0 Vta1 like TFIID_20kDa PF03847.8 EMG45607.1 - 0.00047 20.3 0.3 0.0012 19.1 0.2 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-S PF15630.1 EMG45607.1 - 0.0016 18.5 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 EMG45607.1 - 0.0076 15.9 0.1 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated DUF2972 PF11186.3 EMG45607.1 - 0.061 13.1 0.3 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) Mito_carr PF00153.22 EMG45608.1 - 5.1e-31 106.2 5.5 4.1e-12 45.6 0.0 4.5 4 1 0 4 4 4 4 Mitochondrial carrier protein zf-C2H2_3 PF13878.1 EMG45609.1 - 6.4e-05 22.4 0.2 0.00011 21.6 0.2 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO QRPTase_C PF01729.14 EMG45610.1 - 6.2e-57 191.7 0.1 8.7e-57 191.3 0.1 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EMG45610.1 - 1.3e-26 92.1 0.0 2.8e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain APC10 PF03256.11 EMG45611.1 - 3.4e-45 154.0 0.3 4e-31 108.1 0.0 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex, subunit 10 (APC10) Nop14 PF04147.7 EMG45611.1 - 0.21 9.4 14.0 0.3 8.9 9.7 1.2 1 0 0 1 1 1 0 Nop14-like family SMI1_KNR4 PF09346.5 EMG45612.1 - 3.5e-27 94.9 2.9 1.8e-26 92.6 0.0 3.0 3 0 0 3 3 3 1 SMI1 / KNR4 family (SUKH-1) SurE PF01975.12 EMG45613.1 - 1.5e-42 145.1 0.0 1.9e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE GRAM PF02893.15 EMG45614.1 - 3.8e-22 77.5 0.1 9e-22 76.3 0.1 1.7 1 0 0 1 1 1 1 GRAM domain CYSTM PF12734.2 EMG45614.1 - 5.8 7.0 5.7 1.9 8.5 0.4 2.4 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance AA_permease PF00324.16 EMG45616.1 - 5e-115 384.5 37.8 6.2e-115 384.2 26.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG45616.1 - 2e-35 122.2 42.6 2.6e-35 121.8 29.5 1.1 1 0 0 1 1 1 1 Amino acid permease Ammonium_transp PF00909.16 EMG45617.1 - 1.8e-72 244.0 21.7 1.5e-40 138.9 11.7 2.0 2 0 0 2 2 2 2 Ammonium Transporter Family DUF2953 PF11167.3 EMG45617.1 - 0.021 14.7 0.5 0.26 11.1 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) Mito_carr PF00153.22 EMG45618.1 - 2.3e-71 235.5 0.4 6.5e-23 80.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SOG2 PF10428.4 EMG45619.1 - 4.2e-57 193.7 11.6 4.7e-36 124.4 1.8 4.5 4 1 1 5 5 5 2 RAM signalling pathway protein LRR_8 PF13855.1 EMG45619.1 - 8.6e-22 76.6 19.9 1.6e-11 43.7 1.8 3.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMG45619.1 - 1.4e-14 53.3 8.5 1.2e-05 24.7 0.3 3.9 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMG45619.1 - 8e-11 40.4 5.9 0.29 11.3 0.1 5.3 4 0 0 4 4 4 4 Leucine Rich Repeat LRR_7 PF13504.1 EMG45619.1 - 6.4e-06 25.5 5.0 13 6.5 0.0 5.3 4 0 0 4 4 4 2 Leucine rich repeat VPS28 PF03997.7 EMG45619.1 - 0.21 11.1 6.4 0.15 11.6 0.3 3.4 3 1 0 3 3 3 0 VPS28 protein HMA PF00403.21 EMG45620.1 - 8e-12 45.1 0.0 1.5e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.15 EMG45620.1 - 0.0021 18.2 0.0 0.0036 17.4 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF3419 PF11899.3 EMG45621.1 - 1.1e-142 475.2 0.0 2.3e-142 474.2 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3419) Methyltransf_31 PF13847.1 EMG45621.1 - 2.3e-13 49.9 0.0 1.7e-11 43.9 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMG45621.1 - 5.5e-10 39.6 0.0 2.7e-09 37.3 0.0 2.2 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMG45621.1 - 7.8e-10 39.1 0.0 1.1e-08 35.4 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMG45621.1 - 1.2e-09 38.0 0.0 2.3e-07 30.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMG45621.1 - 1.7e-08 33.8 0.1 3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EMG45621.1 - 4.2e-08 33.7 0.0 2.1e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMG45621.1 - 7.6e-05 22.7 0.0 0.0003 20.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Rsm22 PF09243.5 EMG45621.1 - 0.0075 15.3 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 PCMT PF01135.14 EMG45621.1 - 0.0076 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_28 PF02636.12 EMG45621.1 - 0.0097 15.3 0.0 0.029 13.7 0.0 1.7 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 EMG45621.1 - 0.031 13.6 0.0 0.09 12.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain CM_2 PF01817.16 EMG45622.1 - 2.6e-09 37.0 0.0 0.00024 21.1 0.0 3.5 2 1 0 2 2 2 2 Chorismate mutase type II IL10 PF00726.12 EMG45622.1 - 0.049 12.9 0.0 0.079 12.2 0.0 1.4 1 0 0 1 1 1 0 Interleukin 10 UEV PF05743.8 EMG45623.1 - 3.7e-27 94.4 1.0 6.6e-27 93.6 0.7 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EMG45623.1 - 6.3e-09 35.3 0.0 2.5e-08 33.4 0.0 2.0 2 1 0 2 2 2 1 Vps23 core domain Laminin_II PF06009.7 EMG45623.1 - 0.038 13.7 2.8 0.23 11.2 1.7 2.0 2 0 0 2 2 2 0 Laminin Domain II phiKZ_IP PF12699.2 EMG45623.1 - 0.053 12.4 0.2 0.14 11.0 0.1 1.5 1 1 1 2 2 2 0 phiKZ-like phage internal head proteins ATP_synt_H PF05493.8 EMG45624.1 - 2.4e-24 85.1 2.1 2.6e-24 85.0 1.4 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Git3 PF11710.3 EMG45624.1 - 0.003 17.1 0.5 0.0031 17.0 0.4 1.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 DUF4131 PF13567.1 EMG45624.1 - 0.0073 15.7 0.9 0.0073 15.7 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) MgtE PF01769.11 EMG45624.1 - 0.012 15.9 0.4 0.012 15.8 0.3 1.0 1 0 0 1 1 1 0 Divalent cation transporter UPF0104 PF03706.8 EMG45624.1 - 0.023 13.9 0.4 0.025 13.8 0.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) Frizzled PF01534.12 EMG45624.1 - 0.024 13.4 1.3 0.029 13.1 0.9 1.1 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region DUF2919 PF11143.3 EMG45624.1 - 0.14 11.9 1.8 0.18 11.6 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2919) FixQ PF05545.6 EMG45624.1 - 0.18 11.4 2.9 0.1 12.2 0.7 1.7 1 1 1 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ CAP PF00188.21 EMG45625.1 - 1.6e-14 54.4 7.5 2.4e-14 53.9 5.2 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PsbR PF04725.7 EMG45625.1 - 0.13 12.2 0.8 0.24 11.4 0.5 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa polypeptide PsbR AA_permease PF00324.16 EMG45626.1 - 7.2e-42 143.3 10.0 7.7e-42 143.2 6.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG45626.1 - 5.7e-21 74.5 9.7 6.5e-21 74.3 6.7 1.0 1 0 0 1 1 1 1 Amino acid permease M-factor PF03855.8 EMG45626.1 - 0.51 10.3 2.8 64 3.6 0.1 3.4 3 0 0 3 3 3 0 M-factor AIP3 PF03915.8 EMG45628.1 - 7.4e-157 522.6 13.7 7.4e-157 522.6 9.5 1.8 2 0 0 2 2 2 1 Actin interacting protein 3 Syntaxin_2 PF14523.1 EMG45628.1 - 6.6e-06 26.0 12.2 0.0011 19.0 0.0 4.9 3 1 1 4 4 4 3 Syntaxin-like protein Cob_adeno_trans PF01923.13 EMG45628.1 - 0.75 9.5 8.7 8.1 6.2 0.0 4.4 4 1 1 5 5 5 0 Cobalamin adenosyltransferase UPF0449 PF15136.1 EMG45628.1 - 1.6 9.0 6.4 0.37 11.0 0.4 3.1 4 0 0 4 4 4 0 Uncharacterised protein family UPF0449 CorA PF01544.13 EMG45628.1 - 7.8 5.4 12.6 0.11 11.4 2.6 2.5 3 1 1 4 4 4 0 CorA-like Mg2+ transporter protein Telomerase_RBD PF12009.3 EMG45629.1 - 1.2e-28 99.7 0.3 1.2e-28 99.7 0.2 2.4 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EMG45629.1 - 1e-08 34.8 8.3 8.6e-08 31.7 3.3 2.9 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) dCMP_cyt_deam_1 PF00383.17 EMG45630.1 - 3.2e-08 33.1 0.4 4.7e-08 32.6 0.3 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EMG45630.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase Drf_FH3 PF06367.11 EMG45630.1 - 0.039 13.3 1.0 0.08 12.3 0.7 1.4 1 0 0 1 1 1 0 Diaphanous FH3 Domain SNF5 PF04855.7 EMG45631.1 - 2.3e-66 223.7 3.3 1.6e-64 217.6 2.3 2.2 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 LtrA PF06772.6 EMG45632.1 - 1.2e-24 86.9 13.3 1.9e-24 86.2 9.2 1.3 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) ASXH PF13919.1 EMG45632.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Asx homology domain HBS1_N PF08938.5 EMG45632.1 - 0.14 12.2 0.1 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 HBS1 N-terminus DUF2892 PF11127.3 EMG45632.1 - 6.6 6.6 7.0 1 9.2 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) HIT PF01230.18 EMG45633.1 - 8.1e-25 87.2 0.2 1.2e-24 86.7 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EMG45633.1 - 2.1e-13 50.4 0.5 1.7e-12 47.5 0.0 1.9 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EMG45633.1 - 0.016 14.8 0.8 0.036 13.7 0.6 1.7 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 PSII_Pbs27 PF13326.1 EMG45633.1 - 0.081 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Photosystem II Pbs27 AAA PF00004.24 EMG45634.1 - 5.4e-98 324.3 0.0 5.6e-48 162.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EMG45634.1 - 9.5e-20 70.3 1.8 1.8e-19 69.4 0.5 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EMG45634.1 - 2.1e-14 53.7 0.2 1.4e-07 31.5 0.0 3.2 3 1 0 3 3 3 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EMG45634.1 - 1.7e-13 50.1 0.0 6.4e-06 25.3 0.0 2.9 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EMG45634.1 - 3.3e-12 46.5 0.0 2e-06 27.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EMG45634.1 - 4.1e-12 45.9 0.6 5.1e-06 26.2 0.0 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EMG45634.1 - 9.3e-12 45.8 0.0 0.00013 22.7 0.0 3.4 3 0 0 3 3 2 2 AAA domain CDC48_2 PF02933.12 EMG45634.1 - 1.3e-10 40.7 0.0 3.6e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 EMG45634.1 - 1.4e-10 41.4 2.5 0.0038 17.3 0.1 4.9 3 2 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EMG45634.1 - 2.2e-09 37.5 0.4 0.012 15.6 0.0 3.9 3 2 1 4 4 3 2 AAA ATPase domain TIP49 PF06068.8 EMG45634.1 - 4e-09 35.6 5.3 0.00083 18.1 0.0 3.7 4 0 0 4 4 4 2 TIP49 C-terminus AAA_14 PF13173.1 EMG45634.1 - 1.6e-08 34.4 0.0 0.0013 18.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 EMG45634.1 - 6.6e-08 32.1 1.2 0.0053 16.1 0.1 3.2 4 0 0 4 4 3 2 IstB-like ATP binding protein RNA_helicase PF00910.17 EMG45634.1 - 1.7e-07 31.3 0.0 0.03 14.5 0.0 3.8 4 0 0 4 4 3 2 RNA helicase Zeta_toxin PF06414.7 EMG45634.1 - 2.7e-07 29.8 0.0 0.0039 16.3 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.16 EMG45634.1 - 4.3e-07 29.3 0.6 0.026 13.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ResIII PF04851.10 EMG45634.1 - 1.1e-06 28.6 0.6 0.0026 17.6 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EMG45634.1 - 1.1e-06 28.1 6.8 0.047 13.0 0.1 4.3 2 2 2 4 4 4 2 AAA domain AAA_19 PF13245.1 EMG45634.1 - 2.8e-06 26.9 1.4 0.037 13.7 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain AAA_18 PF13238.1 EMG45634.1 - 5.2e-06 26.7 0.0 0.15 12.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 EMG45634.1 - 1.4e-05 25.3 0.3 0.16 12.2 0.0 4.0 4 1 0 4 4 2 1 ABC transporter AAA_28 PF13521.1 EMG45634.1 - 1.7e-05 24.8 0.0 0.23 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.1 EMG45634.1 - 1.9e-05 24.3 0.1 0.18 11.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain KaiC PF06745.8 EMG45634.1 - 2.2e-05 23.7 4.5 0.39 9.7 0.1 3.9 2 2 2 4 4 4 2 KaiC Sigma54_activat PF00158.21 EMG45634.1 - 2.7e-05 23.7 0.1 0.15 11.5 0.0 3.5 3 1 0 3 3 2 1 Sigma-54 interaction domain Bac_DnaA PF00308.13 EMG45634.1 - 4.1e-05 23.3 0.0 0.02 14.5 0.0 3.0 3 0 0 3 3 2 1 Bacterial dnaA protein Vps4_C PF09336.5 EMG45634.1 - 8.4e-05 22.3 0.1 0.00035 20.4 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain Sigma54_activ_2 PF14532.1 EMG45634.1 - 9.1e-05 22.5 0.0 0.39 10.7 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EMG45634.1 - 0.0001 21.3 0.2 0.35 9.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 EMG45634.1 - 0.00013 21.5 0.0 0.59 9.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain DUF815 PF05673.8 EMG45634.1 - 0.00014 20.8 0.0 0.19 10.6 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF815) PhoH PF02562.11 EMG45634.1 - 0.00015 21.0 2.7 0.068 12.3 0.0 2.7 3 0 0 3 3 2 2 PhoH-like protein AAA_3 PF07726.6 EMG45634.1 - 0.00026 20.5 0.0 0.94 9.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EMG45634.1 - 0.0007 19.2 0.3 3.7 7.1 0.0 3.4 3 0 0 3 3 3 0 NACHT domain AAA_30 PF13604.1 EMG45634.1 - 0.0014 18.2 0.0 2 7.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EMG45634.1 - 0.0015 17.6 0.0 1.6 7.6 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 EMG45634.1 - 0.0066 16.1 1.0 3.4 7.3 0.0 4.2 4 0 0 4 4 4 0 NTPase NB-ARC PF00931.17 EMG45634.1 - 0.0079 15.0 0.7 2.8 6.6 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain T2SE PF00437.15 EMG45634.1 - 0.0096 14.8 0.0 2.9 6.6 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein IPT PF01745.11 EMG45634.1 - 0.014 14.5 0.2 1.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.9 EMG45634.1 - 0.033 13.1 0.0 2.4 7.0 0.0 2.8 2 1 1 3 3 3 0 KAP family P-loop domain AAA_10 PF12846.2 EMG45634.1 - 0.046 13.1 1.1 13 5.1 0.1 3.7 3 1 1 4 4 4 0 AAA-like domain KTI12 PF08433.5 EMG45634.1 - 0.051 12.7 0.0 6.3 5.9 0.0 2.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 UPF0079 PF02367.12 EMG45634.1 - 0.077 12.6 0.1 12 5.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 EMG45634.1 - 0.083 12.3 0.0 14 5.1 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AA_permease PF00324.16 EMG45635.1 - 2.1e-31 108.7 7.1 2.4e-31 108.6 4.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG45635.1 - 8.4e-08 31.1 5.9 9.4e-08 30.9 4.1 1.0 1 0 0 1 1 1 1 Amino acid permease ABC2_membrane_2 PF12679.2 EMG45635.1 - 0.049 12.5 3.4 0.068 12.0 2.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2207 PF09972.4 EMG45635.1 - 0.057 11.9 0.1 0.063 11.8 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3966 PF13110.1 EMG45635.1 - 0.087 12.6 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3966) HEAT_2 PF13646.1 EMG45636.1 - 1.2e-22 79.9 4.9 4.5e-11 42.8 0.3 6.4 2 2 3 6 6 6 5 HEAT repeats HEAT PF02985.17 EMG45636.1 - 1.3e-21 74.6 15.1 0.00014 21.6 0.0 10.5 11 0 0 11 11 10 4 HEAT repeat HEAT_EZ PF13513.1 EMG45636.1 - 1.5e-19 69.8 23.8 1.4e-09 38.1 0.1 11.0 6 3 6 12 12 12 5 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EMG45636.1 - 4.8e-11 42.9 0.3 0.0022 18.3 0.0 5.9 4 2 2 6 6 5 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 EMG45636.1 - 6.2e-11 41.6 4.0 0.00032 19.5 1.9 3.8 3 1 1 4 4 4 3 RNAPII transcription regulator C-terminal ParcG PF10274.4 EMG45636.1 - 1.2e-06 28.6 2.1 0.087 12.7 0.0 4.9 3 2 1 5 5 5 2 Parkin co-regulated protein CLASP_N PF12348.3 EMG45636.1 - 3.1e-05 23.4 0.3 0.59 9.4 0.0 3.8 2 1 1 3 3 3 3 CLASP N terminal RNA_pol_Rpb2_2 PF04561.9 EMG45636.1 - 4.2e-05 23.0 0.1 0.00011 21.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 Arm PF00514.18 EMG45636.1 - 0.00011 21.8 5.3 0.74 9.7 0.0 5.2 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat DNA_alkylation PF08713.6 EMG45636.1 - 0.00041 19.9 0.1 0.0036 16.8 0.0 2.6 2 0 0 2 2 2 1 DNA alkylation repair enzyme CAS_CSE1 PF03378.10 EMG45636.1 - 0.0031 15.8 0.3 0.39 8.9 0.1 3.5 3 1 1 4 4 4 1 CAS/CSE protein, C-terminus CENP-B_dimeris PF09026.5 EMG45636.1 - 4.6 7.5 9.9 13 6.1 0.1 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SNF2_N PF00176.18 EMG45637.1 - 4.2e-81 272.0 0.9 6.9e-81 271.3 0.7 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EMG45637.1 - 5.7e-44 148.6 1.3 3e-43 146.3 0.9 2.4 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 EMG45637.1 - 1.1e-31 109.4 3.6 1.1e-31 109.4 2.5 4.0 4 0 0 4 4 4 1 HAND Helicase_C PF00271.26 EMG45637.1 - 9.5e-16 57.4 0.0 1.2e-14 53.9 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMG45637.1 - 5.2e-08 32.9 0.0 5.2e-08 32.9 0.0 5.1 6 2 1 7 7 7 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EMG45637.1 - 0.00014 21.4 0.0 0.00039 19.9 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 EMG45637.1 - 0.0014 18.0 0.1 0.0043 16.4 0.1 1.8 1 0 0 1 1 1 1 DEAD_2 AAA_22 PF13401.1 EMG45637.1 - 0.043 13.9 0.4 1.1 9.4 0.1 3.3 3 1 0 3 3 3 0 AAA domain AAA_14 PF13173.1 EMG45637.1 - 0.093 12.6 4.7 0.11 12.4 0.1 3.4 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.22 EMG45638.1 - 3.3e-31 108.1 0.0 3.3e-31 108.1 0.0 2.7 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EMG45638.1 - 1.3e-21 76.5 0.0 4.4e-21 74.7 0.0 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EMG45638.1 - 1.1e-11 44.6 6.1 5.7e-08 32.7 0.0 3.9 4 0 0 4 4 4 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMG45638.1 - 4.7e-06 26.5 2.0 7e-06 25.9 0.0 2.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMG45638.1 - 0.0017 18.1 0.2 0.0017 18.1 0.1 4.5 3 1 0 3 3 3 1 Dynamin family ATP_bind_1 PF03029.12 EMG45638.1 - 0.005 16.4 0.0 0.005 16.4 0.0 2.6 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EMG45638.1 - 0.0065 16.6 1.4 0.056 13.5 0.1 3.2 2 1 0 2 2 2 1 AAA domain FeoB_N PF02421.13 EMG45638.1 - 0.007 15.6 0.0 0.03 13.6 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.16 EMG45639.1 - 2.6e-22 78.4 0.0 5.3e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EMG45639.1 - 1.1e-18 67.3 0.3 3.1e-18 65.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMG45639.1 - 4.4e-10 39.0 0.1 1.1e-09 37.8 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EMG45639.1 - 0.00088 18.7 1.2 0.28 10.5 0.1 3.7 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EMG45639.1 - 0.0017 18.2 0.6 0.85 9.4 0.0 2.4 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 EMG45639.1 - 0.0051 15.6 1.4 0.0081 14.9 0.2 1.8 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 EMG45639.1 - 0.009 16.5 0.1 0.092 13.2 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMG45639.1 - 0.089 12.0 0.9 0.46 9.6 0.1 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family zf-RanBP PF00641.13 EMG45640.1 - 1.4e-14 52.9 13.2 5.5e-09 34.9 1.4 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 EMG45640.1 - 6.2e-09 35.3 0.0 0.00065 19.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 EMG45640.1 - 1.1e-08 35.4 0.0 2.3e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Exonuclease RRM_6 PF14259.1 EMG45640.1 - 1.4e-05 24.9 0.0 0.038 13.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Glycos_transf_2 PF00535.21 EMG45641.1 - 3.1e-34 118.1 0.0 3.7e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EMG45641.1 - 3.3e-12 46.6 0.0 7.4e-12 45.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EMG45641.1 - 2.1e-09 36.8 0.0 2.7e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EMG45641.1 - 5.5e-05 22.5 0.0 8.6e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_transf_7N PF13733.1 EMG45641.1 - 0.13 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 ThiF PF00899.16 EMG45642.1 - 4.7e-32 110.6 0.0 1.1e-31 109.5 0.0 1.6 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EMG45642.1 - 1.2e-23 82.4 0.4 1.2e-23 82.4 0.3 2.1 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EMG45642.1 - 4.5e-19 67.5 6.3 7.9e-19 66.7 4.3 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EMG45642.1 - 1.2e-06 28.5 1.6 1.2e-06 28.5 1.1 2.2 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 EMG45642.1 - 0.0021 18.1 0.3 0.0076 16.3 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase CAMP_factor PF07373.6 EMG45642.1 - 0.03 13.8 0.8 0.072 12.5 0.6 1.6 1 0 0 1 1 1 0 CAMP factor (Cfa) Profilin PF00235.14 EMG45643.1 - 3.4e-42 143.3 0.1 3.8e-42 143.2 0.1 1.0 1 0 0 1 1 1 1 Profilin LysM PF01476.15 EMG45643.1 - 0.047 13.5 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 LysM domain SPK PF04435.13 EMG45644.1 - 0.076 12.9 0.1 0.34 10.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF545) YCII PF03795.9 EMG45645.1 - 0.043 13.9 0.0 0.13 12.4 0.0 1.7 1 1 0 1 1 1 0 YCII-related domain ABC2_membrane PF01061.19 EMG45646.1 - 3.3e-82 274.7 52.2 7.6e-45 152.6 13.0 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EMG45646.1 - 7.6e-42 142.8 0.0 1.2e-19 70.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EMG45646.1 - 4.4e-35 119.4 1.4 9.1e-34 115.2 0.0 3.0 2 0 0 2 2 2 1 CDR ABC transporter ABC_trans_N PF14510.1 EMG45646.1 - 6.5e-18 64.6 0.1 2.4e-17 62.8 0.0 2.1 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EMG45646.1 - 7e-09 35.3 0.1 0.00012 21.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EMG45646.1 - 1.2e-07 31.0 0.0 1.2e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 EMG45646.1 - 5.2e-07 29.0 8.2 5.2e-07 29.0 5.7 3.5 3 1 0 3 3 2 2 ABC-2 family transporter protein AAA_29 PF13555.1 EMG45646.1 - 3.1e-05 23.4 1.9 0.0011 18.4 0.3 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EMG45646.1 - 6.2e-05 23.0 0.5 0.00025 21.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EMG45646.1 - 6.8e-05 23.6 0.0 0.0098 16.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EMG45646.1 - 0.0002 21.2 0.0 0.49 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EMG45646.1 - 0.00021 21.6 5.0 0.073 13.3 0.0 4.1 4 1 0 4 4 3 1 AAA domain NACHT PF05729.7 EMG45646.1 - 0.00022 20.9 0.0 0.088 12.4 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.1 EMG45646.1 - 0.00041 20.4 0.0 0.32 11.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.14 EMG45646.1 - 0.00051 19.3 0.0 0.12 11.5 0.0 2.8 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMG45646.1 - 0.00084 19.3 1.3 0.044 13.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.1 EMG45646.1 - 0.0016 18.4 0.1 0.011 15.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMG45646.1 - 0.0016 18.1 0.1 0.18 11.6 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_10 PF12846.2 EMG45646.1 - 0.0018 17.8 0.5 4.3 6.6 0.0 3.6 4 0 0 4 4 4 1 AAA-like domain AAA_30 PF13604.1 EMG45646.1 - 0.0023 17.5 0.1 0.33 10.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain cobW PF02492.14 EMG45646.1 - 0.0027 17.1 2.1 0.11 11.9 0.3 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 EMG45646.1 - 0.0054 16.3 0.3 0.14 11.7 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 EMG45646.1 - 0.0069 16.3 0.3 0.39 10.6 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 EMG45646.1 - 0.021 15.1 3.6 0.043 14.1 0.0 3.2 4 0 0 4 4 2 0 AAA domain Zeta_toxin PF06414.7 EMG45646.1 - 0.033 13.2 0.0 1.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.17 EMG45646.1 - 0.051 13.7 0.1 3.4 7.9 0.0 3.3 3 0 0 3 3 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 EMG45646.1 - 0.054 12.9 0.3 6.7 6.1 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 EMG45646.1 - 0.076 12.5 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 EMG45646.1 - 0.085 12.5 0.5 1.6 8.3 0.0 2.9 3 0 0 3 3 3 0 NTPase AAA PF00004.24 EMG45646.1 - 0.15 12.2 0.0 25 5.0 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.4 EMG45646.1 - 0.24 9.9 0.4 0.51 8.8 0.0 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class GRIM-19 PF06212.7 EMG45647.1 - 1.1e-21 76.9 0.0 1.4e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 GRIM-19 protein zf-C2H2_4 PF13894.1 EMG45648.1 - 1.8e-06 27.8 10.1 0.062 13.6 0.0 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EMG45648.1 - 1.2e-05 25.2 21.9 3e-05 24.0 0.2 4.8 5 0 0 5 5 5 2 Zinc finger, C2H2 type MTHFR_C PF12225.3 EMG45648.1 - 0.0056 16.1 0.6 0.03 13.8 0.3 2.1 2 0 0 2 2 2 1 Methylene-tetrahydrofolate reductase C terminal DUF1443 PF07280.6 EMG45649.1 - 0.67 9.5 3.5 1.6 8.3 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1443) GKAP PF03359.8 EMG45649.1 - 0.92 9.0 7.5 0.73 9.3 4.4 1.4 1 1 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein GTP_EFTU PF00009.22 EMG45652.1 - 4.2e-37 127.4 0.0 7.8e-37 126.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EMG45652.1 - 3.4e-15 55.6 0.0 1.5e-14 53.5 0.0 2.1 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EMG45652.1 - 7.1e-13 48.2 0.0 2e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EMG45652.1 - 1.7e-07 31.2 0.1 4.2e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EMG45652.1 - 7e-05 22.3 0.0 0.00033 20.2 0.0 2.1 1 1 0 1 1 1 1 Elongation factor G, domain IV Zn_clus PF00172.13 EMG45655.1 - 2e-06 27.5 11.0 3.1e-06 26.9 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EMG45655.1 - 2.7e-06 27.1 0.0 5.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold DoxD PF04173.8 EMG45656.1 - 0.053 13.1 0.1 0.089 12.4 0.1 1.3 1 0 0 1 1 1 0 TQO small subunit DoxD RNase_T PF00929.19 EMG45657.1 - 3.1e-20 73.0 0.0 6.9e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EMG45657.1 - 0.041 13.3 0.0 0.09 12.2 0.0 1.6 1 0 0 1 1 1 0 3'-5' exonuclease DUF3591 PF12157.3 EMG45658.1 - 1.1e-178 594.3 8.9 3.4e-177 589.4 6.1 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3591) W2 PF02020.13 EMG45659.1 - 3e-14 52.7 10.1 5.1e-14 51.9 7.0 1.4 1 1 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 EMG45660.1 - 1.6e-09 36.8 15.8 0.00011 21.4 0.3 3.9 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EMG45660.1 - 1.3e-07 31.0 9.8 0.0071 15.8 1.4 3.2 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF2726 PF10881.3 EMG45661.1 - 0.037 13.6 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) Lactamase_B PF00753.22 EMG45661.1 - 0.094 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Fungal_trans_2 PF11951.3 EMG45662.1 - 1.3e-66 224.8 7.0 1.7e-66 224.4 4.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG45662.1 - 8.2e-09 35.2 9.1 1.6e-08 34.2 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydrolase_6 PF13344.1 EMG45664.1 - 1e-29 102.3 0.0 1.7e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMG45664.1 - 9.5e-15 54.0 0.1 2.5e-14 52.7 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EMG45664.1 - 2.1e-09 38.1 0.0 7.2e-09 36.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMG45664.1 - 0.001 19.3 0.0 0.11 12.7 0.0 2.5 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hpt PF01627.18 EMG45665.1 - 1.7e-11 43.9 0.1 5.2e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 Hpt domain NADPH_Ox PF08414.5 EMG45665.1 - 0.027 14.5 0.4 0.1 12.7 0.0 2.1 2 1 0 2 2 2 0 Respiratory burst NADPH oxidase Lipase_3 PF01764.20 EMG45665.1 - 0.054 13.1 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Secretin_N_2 PF07655.8 EMG45665.1 - 0.19 12.1 4.5 0.33 11.3 3.1 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Glyco_transf_22 PF03901.12 EMG45666.1 - 6.5e-75 252.7 26.4 7.2e-75 252.5 18.3 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family zf-primase PF09329.6 EMG45667.1 - 2.2e-14 52.7 0.8 4.7e-14 51.7 0.5 1.6 1 0 0 1 1 1 1 Primase zinc finger Sec34 PF04136.10 EMG45668.1 - 6e-21 74.7 8.8 9.9e-21 74.0 5.0 2.2 2 0 0 2 2 2 1 Sec34-like family DUF948 PF06103.6 EMG45668.1 - 0.073 12.9 1.0 0.3 10.9 0.7 2.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Ctr PF04145.10 EMG45669.1 - 4.9e-27 94.7 20.7 4.2e-25 88.4 14.4 2.1 1 1 0 1 1 1 1 Ctr copper transporter family DUF2434 PF10361.4 EMG45669.1 - 0.014 14.4 1.7 0.019 14.0 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) BPD_transp_1 PF00528.17 EMG45669.1 - 0.066 12.7 1.9 0.27 10.7 0.2 2.0 2 0 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component AA_permease PF00324.16 EMG45672.1 - 7e-130 433.5 45.8 8.9e-130 433.2 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG45672.1 - 4.9e-38 130.7 48.0 6.3e-38 130.4 33.3 1.0 1 0 0 1 1 1 1 Amino acid permease Epimerase PF01370.16 EMG45673.1 - 1.1e-20 74.1 0.0 1.5e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMG45673.1 - 7.8e-14 51.0 0.0 9.7e-14 50.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMG45673.1 - 9.3e-14 50.9 0.0 2.3e-12 46.3 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EMG45673.1 - 1.2e-10 41.7 0.0 3.3e-10 40.2 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EMG45673.1 - 2.3e-05 23.4 0.0 5.9e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EMG45673.1 - 3e-05 24.0 0.1 0.0001 22.2 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 EMG45673.1 - 4.8e-05 22.7 0.0 0.004 16.4 0.0 2.3 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 EMG45673.1 - 0.00018 21.2 0.0 0.00053 19.7 0.0 1.7 2 0 0 2 2 2 1 KR domain RmlD_sub_bind PF04321.12 EMG45673.1 - 0.00052 18.9 0.0 0.0092 14.9 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain Semialdhyde_dh PF01118.19 EMG45673.1 - 0.016 15.4 0.0 0.047 14.0 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EMG45673.1 - 0.036 13.9 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sigma54_activ_2 PF14532.1 EMG45673.1 - 0.097 12.7 0.0 11 6.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain MFS_1 PF07690.11 EMG45674.1 - 4.7e-34 117.6 42.9 4.4e-28 98.0 14.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EMG45674.1 - 8.3e-09 34.4 21.0 0.00034 19.2 9.7 3.0 1 1 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_2 PF13347.1 EMG45674.1 - 3.2e-07 29.1 25.6 0.00045 18.7 4.9 2.9 2 1 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 EMG45674.1 - 5.2e-05 22.0 21.5 5.2e-05 22.0 14.9 2.0 1 1 1 2 2 2 1 Sugar (and other) transporter UNC-93 PF05978.11 EMG45674.1 - 0.22 11.0 8.1 0.19 11.2 1.8 2.7 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 DUF1240 PF06836.7 EMG45674.1 - 2.7 8.2 8.2 14 6.0 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) MFS_1 PF07690.11 EMG45675.1 - 3.8e-45 154.1 49.9 4.4e-42 144.0 36.4 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMG45675.1 - 1.1e-18 66.8 9.9 1.1e-18 66.8 6.9 2.0 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMG45675.1 - 1.7e-10 40.0 16.6 1.7e-10 40.0 11.5 3.6 3 1 1 4 4 4 1 Sugar (and other) transporter MFS_3 PF05977.8 EMG45675.1 - 0.00053 18.2 5.6 0.00053 18.2 3.9 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector DUF4094 PF13334.1 EMG45675.1 - 0.28 11.5 0.1 0.28 11.5 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) NTP_transferase PF00483.18 EMG45676.1 - 1.4e-09 37.6 0.0 2.1e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EMG45676.1 - 0.0015 18.6 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF2726 PF10881.3 EMG45676.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) Hexapep PF00132.19 EMG45677.1 - 8.8e-11 40.8 15.9 8e-05 21.9 0.2 3.9 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EMG45677.1 - 7.7e-08 31.7 9.9 0.0033 16.9 0.4 3.1 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase W2 PF02020.13 EMG45678.1 - 1.1e-17 63.7 4.1 1.1e-17 63.7 2.8 1.7 1 1 1 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon CBS PF00571.23 EMG45679.1 - 3.5e-25 87.5 0.2 7.1e-07 28.9 0.1 5.4 5 0 0 5 5 5 5 CBS domain FA_desaturase PF00487.19 EMG45680.1 - 1.4e-16 60.7 19.0 2.3e-16 60.0 13.1 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EMG45680.1 - 3.6e-13 49.1 0.0 8.4e-13 47.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF997 PF06196.7 EMG45680.1 - 0.072 12.6 1.0 0.17 11.4 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF997) FA_hydroxylase PF04116.8 EMG45680.1 - 7.7 6.9 20.9 11 6.4 0.8 3.3 1 1 2 3 3 3 0 Fatty acid hydroxylase superfamily PX PF00787.19 EMG45682.1 - 3.7e-23 81.4 0.2 4.6e-23 81.1 0.1 1.1 1 0 0 1 1 1 1 PX domain ADH_zinc_N PF00107.21 EMG45683.1 - 1.5e-31 108.6 1.0 2.2e-31 108.1 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMG45683.1 - 1.1e-30 105.5 0.2 2.4e-30 104.5 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EMG45683.1 - 2.4e-05 25.2 0.3 5.1e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMG45684.1 - 1.1e-30 105.6 0.4 1.9e-30 104.8 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMG45684.1 - 2.7e-30 104.5 0.5 4.4e-30 103.9 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMG45684.1 - 3e-06 28.1 0.0 5.7e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase SE PF08491.5 EMG45685.1 - 1.6e-118 394.5 0.0 2e-118 394.1 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EMG45685.1 - 8e-12 44.8 0.0 3.1e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMG45685.1 - 1.7e-09 37.1 0.1 4.9e-06 25.6 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EMG45685.1 - 0.00016 21.7 0.1 0.00038 20.5 0.0 1.6 2 0 0 2 2 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EMG45685.1 - 0.00028 20.5 0.0 0.00042 20.0 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EMG45685.1 - 0.00042 20.2 0.1 0.00092 19.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMG45685.1 - 0.00071 19.9 0.1 0.01 16.2 0.1 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMG45685.1 - 0.0036 17.2 0.0 0.0061 16.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMG45685.1 - 0.0064 15.6 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EMG45685.1 - 0.01 14.7 0.1 0.015 14.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain GDI PF00996.13 EMG45685.1 - 0.015 13.6 0.0 0.022 13.0 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor ApbA PF02558.11 EMG45685.1 - 0.027 13.9 0.1 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 EMG45685.1 - 0.034 14.5 0.1 0.088 13.2 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GIDA PF01134.17 EMG45685.1 - 0.035 12.9 0.2 0.27 10.0 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 EMG45685.1 - 0.039 13.6 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 EMG45685.1 - 0.062 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.10 EMG45685.1 - 0.071 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 EMG45685.1 - 0.077 12.3 0.0 0.22 10.8 0.0 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 EMG45685.1 - 0.15 10.5 0.0 0.22 9.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 EMG45685.1 - 0.23 10.3 0.1 0.78 8.5 0.1 1.8 3 0 0 3 3 3 0 Lycopene cyclase protein Zn_clus PF00172.13 EMG45688.1 - 2.2e-06 27.4 4.2 6.1e-06 26.0 2.9 1.7 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fer4_21 PF14697.1 EMG45688.1 - 0.36 10.7 2.2 0.54 10.1 1.5 1.2 1 0 0 1 1 1 0 4Fe-4S dicluster domain Candida_ALS_N PF11766.3 EMG45689.1 - 4.2e-75 251.8 1.6 9.6e-75 250.6 1.1 1.6 1 0 0 1 1 1 1 Cell-wall agglutinin N-terminal ligand-sugar binding Candida_ALS PF05792.8 EMG45689.1 - 1.6e-46 156.0 222.4 8.9e-09 35.3 8.1 12.5 12 0 0 12 12 12 10 Candida agglutinin-like (ALS) DSPc PF00782.15 EMG45690.1 - 5.4e-07 29.2 0.0 9.1e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMG45690.1 - 2.3e-05 23.8 0.0 6.3e-05 22.4 0.0 1.6 1 1 1 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EMG45690.1 - 0.004 17.4 0.0 0.0063 16.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPn PF14671.1 EMG45690.1 - 0.017 15.0 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half DUF3402 PF11882.3 EMG45691.1 - 4.5e-114 381.6 20.0 4.5e-114 381.6 13.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EMG45691.1 - 1.7e-51 174.8 7.3 1.7e-51 174.8 5.1 2.7 2 1 0 2 2 2 1 N1221-like protein CDP-OH_P_transf PF01066.16 EMG45692.1 - 1.7e-17 63.5 3.2 1.7e-17 63.5 2.2 2.8 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Tom22 PF04281.8 EMG45693.1 - 7.8e-48 161.4 0.5 8.8e-48 161.3 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 GvpG PF05120.7 EMG45693.1 - 0.026 14.3 2.7 0.048 13.4 1.9 1.4 1 0 0 1 1 1 0 Gas vesicle protein G DUF1691 PF07950.6 EMG45694.1 - 6.2e-43 145.2 0.8 3e-21 75.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Sdh_cyt PF01127.17 EMG45694.1 - 0.0028 17.4 1.9 0.039 13.7 0.2 2.3 2 0 0 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit EST1_DNA_bind PF10373.4 EMG45695.1 - 0.013 14.6 1.6 0.016 14.4 1.1 1.1 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain XPA_C PF05181.7 EMG45696.1 - 8.1e-24 82.9 1.0 2.5e-23 81.4 0.1 2.1 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.13 EMG45696.1 - 0.0013 18.3 1.7 0.0013 18.3 1.2 1.9 2 0 0 2 2 2 1 XPA protein N-terminal HSP90 PF00183.13 EMG45697.1 - 1.4e-253 842.1 36.6 1.7e-253 841.8 25.4 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EMG45697.1 - 4.9e-11 42.4 0.0 4.9e-11 42.4 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EMG45697.1 - 6.4e-11 41.9 0.0 1.3e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase V-SNARE_C PF12352.3 EMG45698.1 - 4.7e-11 42.5 2.4 4.7e-11 42.5 1.6 2.4 2 1 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Tmemb_9 PF05434.6 EMG45698.1 - 6.5 6.4 8.2 0.75 9.5 2.4 1.8 2 1 0 2 2 2 0 TMEM9 FAT PF02259.18 EMG45699.1 - 2.6e-76 256.8 5.2 9.8e-76 255.0 3.6 2.1 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EMG45699.1 - 4.4e-30 104.8 0.2 1.3e-29 103.3 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EMG45699.1 - 1e-09 37.6 0.1 3e-09 36.1 0.1 1.8 1 0 0 1 1 1 1 FATC domain DUF605 PF04652.11 EMG45699.1 - 0.0011 18.4 11.7 0.0011 18.4 8.1 3.5 3 0 0 3 3 3 1 Vta1 like TatC PF00902.13 EMG45700.1 - 0.0023 17.3 1.8 0.003 16.9 1.2 1.1 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) DUF3975 PF13126.1 EMG45700.1 - 0.013 15.6 2.8 0.44 10.7 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3975) DUF4064 PF13273.1 EMG45700.1 - 0.047 13.7 1.3 0.079 13.0 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF4190 PF13828.1 EMG45700.1 - 0.75 9.3 6.2 2 8.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) PGP_phosphatase PF09419.5 EMG45701.1 - 3.8e-64 215.0 0.0 4.4e-64 214.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EMG45701.1 - 1.9e-05 24.3 0.0 3.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EMG45701.1 - 0.0097 16.1 0.0 0.016 15.4 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase zf-C3HC4_3 PF13920.1 EMG45702.1 - 2.6e-07 30.2 7.6 2.6e-07 30.2 5.3 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMG45702.1 - 0.001 18.7 10.2 0.001 18.7 7.1 4.3 4 1 0 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMG45702.1 - 0.0017 17.9 9.7 0.0017 17.9 6.8 3.5 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.1 EMG45702.1 - 0.0077 16.4 32.2 0.79 10.2 0.0 7.1 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C3HC4_2 PF13923.1 EMG45702.1 - 0.012 15.6 8.5 0.012 15.6 5.9 4.1 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.21 EMG45702.1 - 0.13 12.6 0.3 0.13 12.6 0.2 7.2 7 1 0 7 7 7 0 Zinc finger, C2H2 type Acyltransferase PF01553.16 EMG45703.1 - 1.9e-20 72.6 0.0 3.4e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Fig1 PF12351.3 EMG45704.1 - 3.2e-42 144.4 10.5 3.2e-42 144.4 7.3 1.8 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EMG45704.1 - 1.7e-05 24.5 19.1 2.3e-05 24.0 13.2 1.2 1 0 0 1 1 1 1 SUR7/PalI family zf-SNAP50_C PF12251.3 EMG45704.1 - 0.0058 16.0 0.4 0.034 13.5 0.0 2.1 2 0 0 2 2 2 1 snRNA-activating protein of 50kDa MW C terminal PgaD PF13994.1 EMG45704.1 - 0.036 13.5 0.4 0.036 13.5 0.3 2.1 3 0 0 3 3 3 0 PgaD-like protein DUF3815 PF12821.2 EMG45704.1 - 1.6 8.6 10.1 0.48 10.3 0.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3815) WD40 PF00400.27 EMG45706.1 - 4.1e-17 61.3 15.6 5.1e-05 22.9 0.0 8.0 8 1 0 8 8 8 4 WD domain, G-beta repeat LisH PF08513.6 EMG45706.1 - 3.2e-09 36.2 0.4 5.9e-09 35.3 0.3 1.5 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 EMG45706.1 - 0.00022 21.0 3.0 0.89 9.2 0.1 4.1 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EMG45706.1 - 0.00025 20.6 0.3 8.1 6.2 0.0 3.7 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat Apc4_WD40 PF12894.2 EMG45706.1 - 0.016 14.6 0.3 0.43 10.1 0.0 3.3 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.1 EMG45706.1 - 0.028 13.5 0.1 1.1 8.3 0.0 3.0 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 EMG45706.1 - 0.045 13.0 0.0 23 4.4 0.0 3.6 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Fzo_mitofusin PF04799.8 EMG45707.1 - 0.1 11.9 6.5 0.072 12.4 1.2 2.4 2 0 0 2 2 2 0 fzo-like conserved region Vps51 PF08700.6 EMG45707.1 - 0.76 9.6 12.8 0.023 14.5 3.2 2.7 3 1 1 4 4 4 0 Vps51/Vps67 CorA PF01544.13 EMG45707.1 - 1.3 7.9 15.6 1.6 7.7 1.9 2.9 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.7 EMG45707.1 - 8.4 6.2 10.3 1.1 9.0 1.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) MFS_1 PF07690.11 EMG45708.1 - 3.3e-44 151.0 19.0 3.3e-44 151.0 13.2 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.23 EMG45709.1 - 2.7e-65 220.3 0.0 3.7e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMG45709.1 - 3.8e-05 24.5 0.1 8.5e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain YejG PF13989.1 EMG45709.1 - 0.076 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 YejG-like protein Ribosomal_S13_N PF08069.7 EMG45710.1 - 8.6e-29 99.1 0.6 1.3e-28 98.5 0.1 1.6 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EMG45710.1 - 7.1e-23 80.1 0.1 1.2e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 Tfb4 PF03850.9 EMG45711.1 - 2.4e-102 341.8 3.0 3e-102 341.6 2.1 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 Rad50_zn_hook PF04423.9 EMG45711.1 - 0.14 11.6 1.3 1.4 8.4 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif dCMP_cyt_deam_1 PF00383.17 EMG45712.1 - 4.4e-24 84.0 0.0 6.2e-24 83.6 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EMG45712.1 - 0.0016 18.2 0.1 0.055 13.3 0.1 2.1 1 1 1 2 2 2 1 Bd3614-like deaminase APOBEC_N PF08210.6 EMG45712.1 - 0.0068 16.0 0.3 0.02 14.4 0.2 1.8 1 1 0 1 1 1 1 APOBEC-like N-terminal domain PADR1 PF08063.7 EMG45712.1 - 0.12 11.8 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 PADR1 (NUC008) domain Pkinase PF00069.20 EMG45713.1 - 6.3e-15 55.0 0.0 1.3e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EMG45713.1 - 6.8e-07 28.9 0.4 0.016 15.0 0.1 4.0 3 1 0 3 3 3 2 WD domain, G-beta repeat Pkinase_Tyr PF07714.12 EMG45713.1 - 5.1e-06 25.7 0.0 1.1e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.17 EMG45713.1 - 6.5e-05 22.6 1.1 0.36 11.0 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat Kinase-like PF14531.1 EMG45713.1 - 0.0064 15.4 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF2783 PF10932.3 EMG45713.1 - 0.027 13.9 0.5 0.091 12.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2783) DUF3639 PF12341.3 EMG45713.1 - 0.043 13.8 2.5 0.39 10.7 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3639) SIP1 PF04938.7 EMG45714.1 - 8.8e-13 48.1 0.2 1.6e-12 47.2 0.2 1.4 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Baculo_VP91_N PF08475.5 EMG45714.1 - 0.048 13.0 0.1 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal DUF2149 PF09919.4 EMG45715.1 - 0.071 13.2 0.1 0.59 10.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) COX15-CtaA PF02628.10 EMG45716.1 - 2.4e-99 332.0 7.7 2.9e-99 331.7 5.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF747 PF05346.6 EMG45717.1 - 4.3e-106 354.7 12.4 7e-106 354.0 8.6 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family RPAP2_Rtr1 PF04181.8 EMG45718.1 - 2.1e-22 79.0 1.9 3.4e-22 78.3 1.3 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family DUF4252 PF14060.1 EMG45718.1 - 0.046 13.2 0.1 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) DUF217 PF02697.9 EMG45718.1 - 0.092 13.0 0.1 0.3 11.3 0.1 1.9 1 1 0 1 1 1 0 Uncharacterized ACR, COG1753 Complex1_LYR PF05347.10 EMG45719.1 - 3.9e-05 23.3 0.6 0.0016 18.2 0.1 2.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMG45719.1 - 0.029 14.5 6.2 0.031 14.4 1.8 2.7 2 1 0 2 2 2 0 Complex1_LYR-like DUF4337 PF14235.1 EMG45719.1 - 0.089 12.6 1.9 0.24 11.2 1.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Complex1_LYR_2 PF13233.1 EMG45719.1 - 6.3 7.3 7.1 1.9 8.9 0.8 2.6 2 0 0 2 2 2 0 Complex1_LYR-like Mpp10 PF04006.7 EMG45720.1 - 0.0055 15.1 23.9 0.0072 14.7 16.6 1.1 1 0 0 1 1 1 1 Mpp10 protein DUF3439 PF11921.3 EMG45720.1 - 0.019 14.7 0.3 0.029 14.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) YL1 PF05764.8 EMG45720.1 - 0.026 14.1 19.1 0.033 13.8 13.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF1510 PF07423.6 EMG45720.1 - 0.048 13.0 19.0 0.056 12.8 13.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SDA1 PF05285.7 EMG45720.1 - 0.051 12.8 23.9 0.064 12.5 16.6 1.1 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 EMG45720.1 - 0.062 11.7 22.3 0.071 11.6 15.5 1.0 1 0 0 1 1 1 0 Daxx Family CENP-T PF15511.1 EMG45720.1 - 0.32 10.1 14.1 0.41 9.8 9.8 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bac_export_2 PF01312.14 EMG45720.1 - 0.69 8.7 4.5 0.45 9.3 1.8 1.6 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family DUF4045 PF13254.1 EMG45720.1 - 0.69 9.1 11.5 0.79 8.9 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CDC45 PF02724.9 EMG45720.1 - 0.81 7.6 14.2 0.94 7.4 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2890 PF11081.3 EMG45720.1 - 0.85 9.6 18.5 1.4 8.9 12.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nop14 PF04147.7 EMG45720.1 - 1 7.2 34.1 0.98 7.2 23.1 1.3 1 1 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 EMG45720.1 - 1.6 7.7 22.2 2 7.3 15.4 1.1 1 0 0 1 1 1 0 BUD22 Ycf1 PF05758.7 EMG45720.1 - 3 5.4 12.0 3.2 5.3 8.3 1.1 1 0 0 1 1 1 0 Ycf1 COPI_C PF06957.6 EMG45720.1 - 3.8 5.9 8.8 5.1 5.5 6.1 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Mem_trans PF03547.13 EMG45720.1 - 5.1 5.2 4.8 6.9 4.8 3.3 1.3 1 0 0 1 1 1 0 Membrane transport protein GAGA_bind PF06217.7 EMG45720.1 - 6.1 6.7 8.0 7.5 6.4 5.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DSPn PF14671.1 EMG45721.1 - 2.3e-47 160.5 0.0 1.4e-46 157.9 0.0 2.0 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EMG45721.1 - 8.9e-22 77.1 0.0 7.7e-21 74.0 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMG45721.1 - 1.1e-05 24.8 0.0 2.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EMG45721.1 - 0.026 14.5 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EMG45721.1 - 0.056 13.6 0.1 0.18 12.0 0.1 1.9 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.7 EMG45721.1 - 0.1 12.0 0.3 0.2 11.1 0.2 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Cofilin_ADF PF00241.15 EMG45722.1 - 8.6e-16 57.9 0.1 9.5e-16 57.8 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ctr PF04145.10 EMG45723.1 - 5.5e-33 114.0 0.2 5.5e-33 114.0 0.1 1.6 2 0 0 2 2 2 1 Ctr copper transporter family Sec8_exocyst PF04048.9 EMG45724.1 - 1.4e-46 157.6 1.3 1.4e-46 157.6 0.9 2.8 4 0 0 4 4 4 1 Sec8 exocyst complex component specific domain ERCC4 PF02732.10 EMG45725.1 - 3.4e-10 39.8 0.1 6.7e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 ERCC4 domain Fes1 PF08609.5 EMG45726.1 - 1.3e-25 89.7 1.5 2.7e-25 88.6 0.4 2.0 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 DUF3388 PF11868.3 EMG45726.1 - 0.0018 17.4 0.2 0.004 16.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3388) PGK PF00162.14 EMG45727.1 - 3.8e-153 509.6 0.3 4.3e-153 509.4 0.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Ctr PF04145.10 EMG45729.1 - 1.2e-33 116.1 0.4 2.5e-33 115.1 0.0 1.7 2 1 0 2 2 2 1 Ctr copper transporter family Oxidored_q2 PF00420.19 EMG45729.1 - 4.7 6.8 8.0 3.3 7.3 0.6 2.6 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L zf-C2H2_4 PF13894.1 EMG45730.1 - 0.016 15.4 15.9 0.28 11.5 0.2 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-Di19 PF05605.7 EMG45730.1 - 0.027 14.5 2.1 0.066 13.3 0.1 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EMG45730.1 - 0.2 12.0 13.4 10 6.6 1.2 4.7 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMG45730.1 - 1.8 9.0 13.3 0.15 12.3 1.3 4.0 3 1 0 3 3 3 0 Zinc-finger double domain AA_permease PF00324.16 EMG45731.1 - 4.4e-115 384.7 53.0 5e-115 384.5 36.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG45731.1 - 2.4e-30 105.4 62.9 2.4e-30 105.4 43.6 1.7 1 1 1 2 2 2 1 Amino acid permease SUN PF03856.8 EMG45732.1 - 9e-102 339.6 18.0 1.3e-101 339.1 12.5 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Sporozoite_P67 PF05642.6 EMG45732.1 - 0.0054 14.6 3.2 0.0086 13.9 2.2 1.3 1 0 0 1 1 1 1 Sporozoite P67 surface antigen GSHPx PF00255.14 EMG45734.1 - 5.1e-42 141.6 0.6 9.2e-42 140.8 0.1 1.6 2 0 0 2 2 2 1 Glutathione peroxidase AhpC-TSA PF00578.16 EMG45734.1 - 7.2e-05 22.4 0.0 0.00018 21.1 0.0 1.7 1 1 1 2 2 2 1 AhpC/TSA family DUF4174 PF13778.1 EMG45734.1 - 0.079 13.0 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) Redoxin PF08534.5 EMG45734.1 - 0.11 12.0 0.0 0.4 10.2 0.0 1.9 1 1 0 1 1 1 0 Redoxin SNARE PF05739.14 EMG45736.1 - 8.8e-08 31.7 2.5 8.8e-08 31.7 1.7 3.2 3 0 0 3 3 3 1 SNARE domain V-SNARE_C PF12352.3 EMG45736.1 - 0.29 11.2 5.9 0.33 11.0 0.7 3.2 3 1 1 4 4 4 0 Snare region anchored in the vesicle membrane C-terminus DUF1664 PF07889.7 EMG45736.1 - 6.6 6.5 9.1 4.6 7.0 1.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FA_desaturase PF00487.19 EMG45737.1 - 1.1e-22 80.7 17.4 1.5e-22 80.2 12.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EMG45737.1 - 2.9e-06 27.3 0.0 5.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) TMEM213 PF15192.1 EMG45737.1 - 0.025 14.5 3.9 0.032 14.2 0.3 2.3 2 0 0 2 2 2 0 TMEM213 family Med18 PF09637.5 EMG45738.1 - 0.14 11.7 0.0 0.14 11.6 0.0 1.0 1 0 0 1 1 1 0 Med18 protein P21-Arc PF04062.9 EMG45739.1 - 9.6e-83 276.2 0.1 1.1e-82 276.0 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit DUF1493 PF07377.7 EMG45739.1 - 0.089 12.8 0.2 0.39 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1493) WD40 PF00400.27 EMG45740.1 - 1.3e-18 66.1 10.4 6.8e-05 22.6 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat GSHPx PF00255.14 EMG45741.1 - 5.3e-38 128.7 0.3 7.7e-38 128.1 0.2 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.5 EMG45741.1 - 0.036 13.6 0.2 0.22 11.0 0.2 2.1 1 1 0 1 1 1 0 Redoxin DUF4174 PF13778.1 EMG45741.1 - 0.043 13.8 0.0 0.085 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) GSHPx PF00255.14 EMG45742.1 - 4.8e-45 151.3 0.2 6.2e-45 151.0 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EMG45742.1 - 5.2e-05 22.9 0.1 0.00031 20.4 0.1 2.0 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EMG45742.1 - 0.00016 21.2 0.1 0.00066 19.2 0.1 1.8 1 1 0 1 1 1 1 Redoxin SCO1-SenC PF02630.9 EMG45742.1 - 0.011 15.3 0.1 0.83 9.2 0.0 2.6 2 1 1 3 3 3 0 SCO1/SenC DUF4174 PF13778.1 EMG45742.1 - 0.027 14.5 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) Inositol_P PF00459.20 EMG45743.1 - 2.2e-55 187.8 0.0 9e-55 185.8 0.1 1.9 2 0 0 2 2 2 1 Inositol monophosphatase family Lipase_3 PF01764.20 EMG45743.1 - 9.1e-29 99.8 0.1 2.3e-28 98.5 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Thioesterase PF00975.15 EMG45743.1 - 0.00051 20.3 0.1 0.024 14.8 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain HA2 PF04408.18 EMG45744.1 - 1.3e-16 60.4 0.0 1.3e-16 60.4 0.0 3.0 3 1 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EMG45744.1 - 2.4e-15 56.1 0.0 3.2e-14 52.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EMG45744.1 - 6.2e-14 51.7 0.0 1.6e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 EMG45744.1 - 7.8e-07 29.2 0.1 1.7e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EMG45744.1 - 4e-06 26.4 0.3 1e-05 25.0 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.1 EMG45744.1 - 0.0029 17.1 0.1 0.0096 15.4 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EMG45744.1 - 0.014 14.6 0.0 0.041 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EMG45744.1 - 0.047 13.9 0.2 0.047 13.9 0.2 2.7 1 1 1 2 2 1 0 ABC transporter Med12 PF09497.5 EMG45744.1 - 0.13 12.2 0.0 1.9 8.5 0.0 2.7 3 0 0 3 3 3 0 Transcription mediator complex subunit Med12 AAA_16 PF13191.1 EMG45744.1 - 0.21 11.5 0.6 17 5.3 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain TFIIF_alpha PF05793.7 EMG45744.1 - 0.41 8.9 29.4 0.56 8.5 20.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) tRNA-synt_1b PF00579.20 EMG45745.1 - 5e-71 239.2 0.0 7.7e-71 238.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) AA_permease PF00324.16 EMG45746.1 - 1.9e-86 290.3 34.1 2.4e-86 290.0 23.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG45746.1 - 1.6e-23 82.9 34.0 2.4e-23 82.3 23.6 1.3 1 0 0 1 1 1 1 Amino acid permease SH3BGR PF04908.10 EMG45747.1 - 2e-05 24.4 0.0 2e-05 24.4 0.0 3.5 3 0 0 3 3 3 1 SH3-binding, glutamic acid-rich protein SCF PF02404.10 EMG45747.1 - 0.039 13.1 3.7 0.048 12.8 0.3 2.5 2 0 0 2 2 2 0 Stem cell factor Glutaredoxin PF00462.19 EMG45747.1 - 0.12 12.3 0.0 0.41 10.6 0.0 2.0 1 0 0 1 1 1 0 Glutaredoxin Sec20 PF03908.8 EMG45748.1 - 0.018 14.6 0.4 0.037 13.7 0.3 1.4 1 0 0 1 1 1 0 Sec20 GRAM PF02893.15 EMG45749.1 - 1.2e-17 63.1 0.0 2.5e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 GRAM domain ABC2_membrane_3 PF12698.2 EMG45749.1 - 0.016 14.2 0.7 0.016 14.2 0.5 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein IlvC PF01450.14 EMG45750.1 - 1.4e-47 161.2 0.0 2.4e-47 160.5 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.7 EMG45750.1 - 6.5e-44 149.2 0.0 9.4e-44 148.6 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EMG45750.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase SH3_2 PF07653.12 EMG45750.1 - 0.12 11.8 0.1 0.27 10.7 0.1 1.6 1 0 0 1 1 1 0 Variant SH3 domain Topoisom_I_N PF02919.10 EMG45751.1 - 4.6e-102 339.8 0.7 4.6e-102 339.8 0.5 3.5 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EMG45751.1 - 3e-83 278.5 4.3 3e-83 278.5 3.0 2.7 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EMG45751.1 - 4e-31 106.4 0.4 4e-31 106.4 0.3 2.3 2 0 0 2 2 2 1 C-terminal topoisomerase domain DUF1675 PF07897.6 EMG45751.1 - 0.92 9.3 18.4 2.7 7.7 12.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Ly49 PF08391.5 EMG45752.1 - 0.00053 20.0 0.4 0.0014 18.7 0.2 1.7 1 1 0 1 1 1 1 Ly49-like protein, N-terminal region DUF1180 PF06679.7 EMG45752.1 - 0.017 14.9 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Herpes_gE PF02480.11 EMG45752.1 - 0.02 13.1 0.3 0.024 12.9 0.2 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Herpes_glycop PF01528.11 EMG45752.1 - 0.025 13.3 0.0 0.033 12.8 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein M EphA2_TM PF14575.1 EMG45752.1 - 0.072 13.4 0.2 0.19 12.1 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 EMG45752.1 - 0.34 10.6 2.5 0.41 10.3 0.8 1.8 1 1 0 1 1 1 0 TMEM154 protein family Sec-ASP3 PF15432.1 EMG45753.1 - 0.022 14.7 0.1 0.04 13.8 0.0 1.5 2 0 0 2 2 2 0 Accessory Sec secretory system ASP3 DUF2076 PF09849.4 EMG45754.1 - 7e-09 36.0 9.9 8.1e-09 35.8 6.8 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EMG45754.1 - 7.3e-05 22.5 4.3 0.00013 21.7 3.0 1.4 1 0 0 1 1 1 1 CHCH domain DUF605 PF04652.11 EMG45754.1 - 0.072 12.4 10.6 0.086 12.2 7.4 1.1 1 0 0 1 1 1 0 Vta1 like Paramyxo_PNT PF13825.1 EMG45754.1 - 0.22 10.7 4.3 0.25 10.5 3.0 1.1 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus Bindin PF02084.10 EMG45754.1 - 0.23 11.4 4.1 0.27 11.2 2.9 1.1 1 0 0 1 1 1 0 Bindin Gly-zipper_OmpA PF13436.1 EMG45754.1 - 0.39 10.3 11.2 0.13 11.9 5.9 1.8 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Pex14_N PF04695.8 EMG45754.1 - 0.68 9.9 9.8 2.8 7.9 2.6 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region COX6B PF02297.12 EMG45754.1 - 0.99 9.4 6.6 1.6 8.8 4.6 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb PAT1 PF09770.4 EMG45754.1 - 2 6.5 15.1 2.4 6.3 10.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Nucleoporin_FG PF13634.1 EMG45754.1 - 6.3 7.0 18.7 11 6.2 13.0 1.4 1 1 0 1 1 1 0 Nucleoporin FG repeat region AA_permease PF00324.16 EMG45755.1 - 9.3e-16 57.2 10.0 1e-15 57.0 6.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG45755.1 - 0.0015 17.1 6.2 0.0017 16.9 4.3 1.0 1 0 0 1 1 1 1 Amino acid permease Tht1 PF04163.7 EMG45756.1 - 2.9e-19 68.9 28.1 6.2e-19 67.8 19.5 1.6 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein AAA_7 PF12775.2 EMG45756.1 - 0.029 13.4 1.8 0.41 9.6 0.1 2.2 1 1 1 2 2 2 0 P-loop containing dynein motor region D3 Taxilin PF09728.4 EMG45756.1 - 0.59 9.1 15.9 1.6 7.7 11.0 1.7 1 1 0 1 1 1 0 Myosin-like coiled-coil protein YtxH PF12732.2 EMG45756.1 - 1.4 9.3 6.2 10 6.5 0.3 3.6 3 1 0 3 3 3 0 YtxH-like protein AA_permease PF00324.16 EMG45757.1 - 1.6e-71 241.0 21.2 2e-71 240.8 14.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG45757.1 - 6.9e-18 64.3 27.1 6.9e-18 64.3 18.8 1.7 1 1 1 2 2 2 1 Amino acid permease OppC_N PF12911.2 EMG45757.1 - 0.88 8.9 5.1 0.37 10.1 0.1 2.7 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF2101 PF09874.4 EMG45757.1 - 1.7 8.0 7.0 3.4 7.0 4.9 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) Rad52_Rad22 PF04098.10 EMG45758.1 - 6.7e-61 204.5 0.0 6.7e-61 204.5 0.0 1.6 2 0 0 2 2 2 1 Rad52/22 family double-strand break repair protein ThiF PF00899.16 EMG45759.1 - 1.6e-36 125.1 0.4 8.2e-36 122.8 0.0 2.0 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 EMG45759.1 - 1e-28 98.8 1.0 1.6e-28 98.2 0.7 1.3 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 EMG45759.1 - 1.8e-22 78.6 0.9 1.8e-22 78.6 0.6 1.8 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EMG45759.1 - 1.1e-16 59.9 2.3 1.8e-16 59.2 1.6 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EMG45759.1 - 2.1e-05 24.6 0.0 4.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.1 EMG45759.1 - 0.00094 19.2 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain MoeZ_MoeB PF05237.8 EMG45759.1 - 0.005 16.4 0.3 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 MoeZ/MoeB domain Ecm33 PF12454.3 EMG45759.1 - 0.064 13.1 0.7 0.12 12.3 0.5 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Gmx_para_CXXCG PF09535.5 EMG45759.1 - 0.16 10.9 0.1 10 5.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (Gmx_para_CXXCG) Abhydrolase_6 PF12697.2 EMG45760.1 - 2.4e-17 63.6 0.0 3.1e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMG45760.1 - 7e-09 35.5 0.1 6.1e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMG45760.1 - 0.00039 20.1 0.0 0.00059 19.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EMG45760.1 - 0.0042 16.7 0.0 0.0074 15.8 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase DUF2305 PF10230.4 EMG45760.1 - 0.0061 15.9 0.1 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) SUR7 PF06687.7 EMG45761.1 - 9.7e-47 159.2 3.5 1.4e-46 158.7 2.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EMG45761.1 - 0.023 14.4 7.7 0.24 11.0 0.7 2.4 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction EphA2_TM PF14575.1 EMG45761.1 - 0.036 14.4 0.0 14 6.1 0.0 2.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4044 PF13253.1 EMG45761.1 - 0.82 8.8 3.8 2 7.6 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Na_H_Exchanger PF00999.16 EMG45763.1 - 1.3e-67 228.0 35.3 1.6e-67 227.7 24.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ndc1_Nup PF09531.5 EMG45764.1 - 2e-98 330.3 3.1 2.4e-98 330.1 2.1 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Spo0A_C PF08769.6 EMG45765.1 - 0.14 12.0 0.8 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal ERCC4 PF02732.10 EMG45766.1 - 4.7e-26 91.2 0.5 1.1e-25 90.0 0.4 1.6 1 0 0 1 1 1 1 ERCC4 domain HTH_45 PF14947.1 EMG45766.1 - 0.031 14.0 0.4 0.59 9.9 0.0 3.1 4 0 0 4 4 4 0 Winged helix-turn-helix DUF4364 PF14277.1 EMG45766.1 - 0.051 13.1 0.0 0.051 13.1 0.0 3.3 6 0 0 6 6 6 0 Domain of unknown function (DUF4364) Mvb12 PF09452.5 EMG45766.1 - 0.06 13.5 0.7 3.7 7.7 0.1 3.0 3 0 0 3 3 3 0 ESCRT-I subunit Mvb12 CITED PF04487.7 EMG45766.1 - 0.24 11.6 1.8 0.4 10.8 0.7 1.6 1 1 1 2 2 2 0 CITED Oxidored_FMN PF00724.15 EMG45769.1 - 2.1e-114 382.1 0.0 2.3e-114 381.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Mito_carr PF00153.22 EMG45770.1 - 4.1e-32 109.7 4.4 5e-15 54.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TPT PF03151.11 EMG45771.1 - 3.8e-25 88.3 10.3 3.8e-25 88.3 7.1 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EMG45771.1 - 3.7e-08 33.4 29.1 3.1e-06 27.2 4.4 3.4 3 1 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 EMG45771.1 - 1.2e-06 27.7 29.5 2.6e-06 26.5 20.5 1.5 1 1 0 1 1 1 1 UAA transporter family Cu-oxidase_3 PF07732.10 EMG45772.1 - 2.7e-38 130.3 0.4 3.4e-38 129.9 0.3 1.1 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.17 EMG45772.1 - 8.7e-05 22.4 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMG45772.1 - 0.0023 17.4 0.2 0.016 14.7 0.2 2.0 1 1 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMG45773.1 - 3.3e-46 156.2 6.2 3.8e-41 139.8 0.7 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EMG45773.1 - 3.9e-45 152.3 2.1 6.7e-42 141.9 0.1 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EMG45773.1 - 1.6e-37 128.8 2.3 5.5e-31 107.6 0.9 3.1 3 0 0 3 3 3 2 Multicopper oxidase C1q PF00386.16 EMG45773.1 - 0.015 15.2 0.0 0.34 10.9 0.0 2.8 3 0 0 3 3 3 0 C1q domain Cupredoxin_1 PF13473.1 EMG45773.1 - 0.032 14.1 0.0 6.9 6.6 0.0 3.3 3 0 0 3 3 3 0 Cupredoxin-like domain Costars PF14705.1 EMG45774.1 - 0.078 12.9 0.7 0.23 11.4 0.1 2.1 2 0 0 2 2 2 0 Costars Syntaxin_2 PF14523.1 EMG45774.1 - 0.25 11.3 36.7 0.26 11.3 3.1 4.3 1 1 3 4 4 4 0 Syntaxin-like protein PilO PF04350.8 EMG45774.1 - 0.88 9.4 14.0 1.2 9.0 0.5 3.6 2 1 0 3 3 3 0 Pilus assembly protein, PilO HLH PF00010.21 EMG45774.1 - 3.2 7.5 8.5 32 4.3 0.0 4.5 4 1 0 4 4 4 0 Helix-loop-helix DNA-binding domain tRNA-synt_2b PF00587.20 EMG45775.1 - 1.9e-28 99.2 0.0 3.5e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EMG45775.1 - 1.2e-06 28.5 5.5 1.2e-06 28.5 3.8 1.8 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Syntaxin-6_N PF09177.6 EMG45775.1 - 0.014 15.7 0.4 0.038 14.4 0.3 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal IncA PF04156.9 EMG45775.1 - 0.042 13.4 1.6 0.083 12.4 1.1 1.4 1 0 0 1 1 1 0 IncA protein tRNA-synt_His PF13393.1 EMG45775.1 - 0.11 11.5 0.1 1.5 7.7 0.0 2.1 2 0 0 2 2 2 0 Histidyl-tRNA synthetase Flu_NS2 PF00601.14 EMG45775.1 - 0.16 12.2 2.2 0.18 12.0 0.2 2.1 3 0 0 3 3 3 0 Influenza non-structural protein (NS2) NuA4 PF09340.5 EMG45775.1 - 0.17 11.5 1.8 2.6 7.7 0.4 2.6 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 GAS PF13851.1 EMG45775.1 - 0.81 8.8 9.3 0.15 11.2 2.0 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.15 EMG45775.1 - 2.6 7.8 10.4 0.44 10.3 3.2 2.5 2 1 0 2 2 2 0 Prefoldin subunit FlxA PF14282.1 EMG45775.1 - 3.7 7.5 8.8 1.3 9.0 3.5 2.1 2 0 0 2 2 2 0 FlxA-like protein AA_permease PF00324.16 EMG45776.1 - 1.7e-116 389.4 38.8 1.9e-116 389.2 26.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG45776.1 - 1.2e-33 116.2 42.4 1.5e-33 115.9 29.4 1.1 1 0 0 1 1 1 1 Amino acid permease PAGK PF15284.1 EMG45776.1 - 0.064 13.0 0.2 2.9 7.7 0.1 2.9 2 0 0 2 2 2 0 Phage-encoded virulence factor GSHPx PF00255.14 EMG45777.1 - 1.4e-37 127.3 0.2 2e-37 126.8 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase GSHPx PF00255.14 EMG45778.1 - 2.2e-41 139.5 0.4 2.8e-41 139.2 0.3 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EMG45778.1 - 0.068 12.8 0.2 0.48 10.1 0.1 2.0 1 1 0 1 1 1 0 AhpC/TSA family DUF4174 PF13778.1 EMG45778.1 - 0.074 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) Redoxin PF08534.5 EMG45778.1 - 0.14 11.7 0.3 0.79 9.2 0.2 1.9 1 1 0 1 1 1 0 Redoxin Ribosomal_L1 PF00687.16 EMG45779.1 - 1.3e-51 175.1 9.7 1.3e-51 175.1 6.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family Cu-oxidase_2 PF07731.9 EMG45780.1 - 1.1e-46 157.8 1.7 5.7e-41 139.2 0.1 2.8 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EMG45780.1 - 6.4e-44 148.4 1.0 1.3e-40 137.7 0.1 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EMG45780.1 - 8.2e-38 129.8 2.1 6.5e-33 113.8 0.8 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMG45781.1 - 5.7e-42 142.5 1.8 1.1e-41 141.5 1.2 1.5 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.17 EMG45781.1 - 0.0038 17.1 0.2 0.0038 17.1 0.1 2.7 3 1 0 3 3 3 1 Multicopper oxidase C1q PF00386.16 EMG45781.1 - 0.069 13.1 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 C1q domain DUF2613 PF11021.3 EMG45781.1 - 0.11 12.2 0.0 0.34 10.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Mlp PF03304.8 EMG45782.1 - 0.18 11.7 11.6 0.31 11.0 0.0 3.0 2 1 0 2 2 2 0 Mlp lipoprotein family Lgl_C PF08596.5 EMG45783.1 - 9.5e-128 426.0 0.5 2.1e-127 424.8 0.2 1.6 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EMG45783.1 - 0.014 15.2 0.3 6.2 6.8 0.0 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat NifU_N PF01592.11 EMG45783.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 NifU-like N terminal domain gerPA PF10676.4 EMG45783.1 - 3.1 7.6 8.4 1 9.2 0.3 3.3 2 1 1 3 3 3 0 Spore germination protein gerPA/gerPF DPM2 PF07297.7 EMG45784.1 - 1.3e-31 108.6 0.2 1.5e-31 108.4 0.1 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Adap_comp_sub PF00928.16 EMG45785.1 - 2.3e-40 138.3 4.8 5.6e-34 117.4 0.3 2.1 2 0 0 2 2 2 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EMG45785.1 - 0.00011 21.8 0.1 0.00024 20.8 0.1 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.1 EMG45785.1 - 0.091 12.3 0.1 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 Regulated-SNARE-like domain V_ATPase_I PF01496.14 EMG45786.1 - 2.7e-258 858.8 22.9 2.8e-204 680.2 8.1 2.0 2 0 0 2 2 2 2 V-type ATPase 116kDa subunit family DUF3702 PF12486.3 EMG45786.1 - 0.054 13.1 0.1 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 ImpA domain protein BLOC1_2 PF10046.4 EMG45786.1 - 0.065 13.3 4.7 0.36 10.9 0.9 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sel1 PF08238.7 EMG45787.1 - 3.5e-22 78.3 18.6 7.9e-06 26.3 0.0 10.4 12 0 0 12 12 12 6 Sel1 repeat TPR_11 PF13414.1 EMG45787.1 - 3.1e-06 26.7 4.0 0.089 12.4 0.0 4.8 3 1 1 4 4 4 3 TPR repeat TPR_16 PF13432.1 EMG45787.1 - 0.0012 19.4 0.0 17 6.2 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMG45787.1 - 0.044 13.7 3.3 3.8 7.5 0.0 4.6 5 2 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMG45787.1 - 0.14 11.8 10.2 3.5 7.3 0.0 6.2 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMG45787.1 - 2.7 8.1 0.0 2.7 8.1 0.0 6.7 9 2 0 9 9 9 0 Tetratricopeptide repeat MIT PF04212.13 EMG45787.1 - 7 6.6 7.6 14 5.6 0.0 4.5 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain Dna2 PF08696.6 EMG45788.1 - 5.5e-62 208.7 0.2 5.5e-62 208.7 0.2 2.4 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_11 PF13086.1 EMG45788.1 - 9.4e-39 133.3 4.6 2.7e-19 69.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_12 PF13087.1 EMG45788.1 - 8.5e-25 87.3 2.0 8.6e-25 87.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EMG45788.1 - 5.9e-11 42.3 0.0 1e-09 38.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMG45788.1 - 7.5e-09 35.2 0.0 1.5e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Cas_Cas4 PF01930.12 EMG45788.1 - 2.6e-07 30.7 0.2 7.1e-07 29.2 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function DUF83 Helicase_RecD PF05127.9 EMG45788.1 - 2.3e-05 24.0 0.0 7.3e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 EMG45788.1 - 0.00033 19.7 0.3 0.075 11.9 0.1 2.5 2 0 0 2 2 2 1 PIF1-like helicase Viral_helicase1 PF01443.13 EMG45788.1 - 0.0007 19.1 2.2 0.19 11.2 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase SRP54 PF00448.17 EMG45788.1 - 0.0011 18.4 0.3 0.0037 16.7 0.0 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 EMG45788.1 - 0.0087 16.0 0.1 0.047 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 EMG45788.1 - 0.014 14.6 0.0 1.5 7.9 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EMG45788.1 - 0.016 14.2 0.0 0.046 12.8 0.0 1.7 1 0 0 1 1 1 0 KaiC MobB PF03205.9 EMG45788.1 - 0.017 14.8 0.1 0.049 13.3 0.1 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EMG45788.1 - 0.054 13.2 0.2 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 NTPase AAA PF00004.24 EMG45788.1 - 0.08 13.1 0.7 0.3 11.2 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EMG45788.1 - 0.1 12.4 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EMG45788.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Nop PF01798.13 EMG45789.1 - 1.3e-60 203.0 0.4 3.9e-60 201.4 0.3 1.9 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EMG45789.1 - 3.1e-26 90.9 0.0 6.7e-26 89.8 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EMG45789.1 - 1.8e-20 72.8 2.1 1.8e-20 72.8 1.4 3.2 2 1 0 2 2 2 1 NOP5NT (NUC127) domain GAGA_bind PF06217.7 EMG45789.1 - 5.3 6.9 28.0 1.1 9.1 16.1 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family TPR_11 PF13414.1 EMG45790.1 - 5e-16 58.1 0.4 1.5e-11 43.7 0.0 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EMG45790.1 - 1.9e-12 46.2 0.0 0.0011 18.5 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMG45790.1 - 2.4e-10 39.4 0.0 0.0095 15.7 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMG45790.1 - 2.3e-06 27.4 0.2 0.1 12.5 0.0 2.7 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMG45790.1 - 0.00034 20.1 0.1 0.8 9.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 EMG45790.1 - 0.021 14.0 0.0 2.8 7.2 0.0 2.5 2 0 0 2 2 2 0 SHNi-TPR TPR_9 PF13371.1 EMG45790.1 - 0.052 13.4 0.0 0.38 10.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 EMG45791.1 - 1.2e-64 217.9 0.0 3.7e-64 216.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG45791.1 - 4.1e-33 114.5 0.3 3.7e-32 111.4 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG45791.1 - 6e-06 25.4 0.0 7.9e-05 21.7 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMG45791.1 - 0.0093 15.0 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pex14_N PF04695.8 EMG45791.1 - 0.01 15.9 2.5 0.01 15.9 1.7 5.3 3 1 1 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_M3 PF01432.15 EMG45792.1 - 2e-106 356.7 0.1 2.7e-106 356.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 EMG45792.1 - 0.2 11.0 0.2 0.31 10.3 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like AA_permease PF00324.16 EMG45793.1 - 4.5e-120 401.2 34.9 5.1e-120 401.0 24.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG45793.1 - 1e-32 113.2 37.6 1.2e-32 112.9 26.1 1.1 1 0 0 1 1 1 1 Amino acid permease HLH PF00010.21 EMG45795.1 - 3e-17 62.0 0.1 3e-17 62.0 0.1 2.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain SWIM PF04434.12 EMG45796.1 - 0.0077 15.6 0.4 0.42 10.1 0.0 2.3 2 0 0 2 2 2 2 SWIM zinc finger End_beta_barrel PF12195.3 EMG45796.1 - 0.069 12.8 0.1 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Beta barrel domain of bacteriophage endosialidase Rtt106 PF08512.7 EMG45797.1 - 1e-20 73.5 0.7 3.3e-20 71.8 0.4 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like ORC3_N PF07034.6 EMG45797.1 - 0.11 11.3 0.8 2.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 3 N-terminus Aminotran_1_2 PF00155.16 EMG45798.1 - 2.1e-20 73.0 0.0 2.4e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EMG45798.1 - 0.00047 18.8 0.0 0.0036 15.9 0.0 2.2 3 0 0 3 3 3 1 Alanine-glyoxylate amino-transferase PqqD PF05402.7 EMG45798.1 - 0.063 13.3 0.0 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) PX PF00787.19 EMG45799.1 - 3.1e-15 55.9 0.7 9.5e-15 54.3 0.0 2.1 2 1 0 2 2 2 1 PX domain SNARE PF05739.14 EMG45799.1 - 2.2e-12 46.4 6.9 2.2e-12 46.4 4.8 2.2 2 0 0 2 2 2 1 SNARE domain Activator-TraM PF11657.3 EMG45799.1 - 0.093 12.2 2.5 0.56 9.6 0.6 2.5 2 1 0 2 2 2 0 Transcriptional activator TraM Phage_GPO PF05929.6 EMG45799.1 - 8.9 5.4 9.2 15 4.7 0.1 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2417 PF10329.4 EMG45800.1 - 3.2e-79 265.6 6.4 4.6e-79 265.0 4.4 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 EMG45800.1 - 1.1e-11 45.1 0.0 2.3e-11 44.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMG45800.1 - 3e-05 23.7 0.0 6.6e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EMG45800.1 - 4.1e-05 23.9 0.0 5.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 EMG45800.1 - 0.00089 18.8 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold FHA PF00498.21 EMG45801.1 - 7.8e-13 48.3 0.0 2.2e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 FHA domain PIG-S PF10510.4 EMG45801.1 - 5.8e-09 35.1 10.2 0.00013 20.7 0.1 3.2 3 0 0 3 3 3 2 Phosphatidylinositol-glycan biosynthesis class S protein zf-RING_2 PF13639.1 EMG45801.1 - 7e-09 35.3 7.5 1.2e-08 34.5 5.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EMG45801.1 - 0.00012 21.6 4.6 0.00023 20.8 3.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMG45801.1 - 0.00043 20.2 7.9 0.0009 19.2 5.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMG45801.1 - 0.00064 19.7 6.5 0.0013 18.8 4.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger PHD PF00628.24 EMG45801.1 - 0.00099 18.7 4.4 0.0021 17.6 3.0 1.6 1 0 0 1 1 1 1 PHD-finger zf-C3HC4 PF00097.20 EMG45801.1 - 0.0012 18.4 6.1 0.0024 17.5 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMG45801.1 - 0.0018 18.0 3.9 0.0034 17.1 2.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Myc_N PF01056.13 EMG45801.1 - 0.0022 17.2 5.0 0.004 16.3 3.4 1.4 1 0 0 1 1 1 1 Myc amino-terminal region Podoplanin PF05808.6 EMG45801.1 - 0.015 14.8 2.4 0.03 13.8 1.7 1.4 1 0 0 1 1 1 0 Podoplanin Sen15 PF09631.5 EMG45801.1 - 0.088 13.0 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Sen15 protein zf-RING_UBOX PF13445.1 EMG45801.1 - 0.15 11.7 3.3 0.45 10.2 2.3 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING-like PF08746.6 EMG45801.1 - 0.86 9.6 4.4 1.7 8.6 3.1 1.5 1 0 0 1 1 1 0 RING-like domain FAM176 PF14851.1 EMG45801.1 - 2.7 7.6 5.8 6.8 6.3 4.0 1.6 1 0 0 1 1 1 0 FAM176 family Acetyltransf_1 PF00583.19 EMG45802.1 - 3.2e-14 52.7 0.0 7.5e-14 51.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMG45802.1 - 6.7e-06 26.1 0.0 1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMG45802.1 - 0.00011 22.2 0.0 0.00015 21.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMG45802.1 - 0.0002 21.5 0.0 0.00031 20.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMG45802.1 - 0.00039 20.3 0.0 0.0005 20.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Mec-17 PF05301.6 EMG45802.1 - 0.025 14.5 0.0 0.092 12.6 0.0 1.8 1 1 1 2 2 2 0 Touch receptor neuron protein Mec-17 Acetyltransf_9 PF13527.1 EMG45802.1 - 0.09 12.6 0.0 0.37 10.6 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short_C2 PF13561.1 EMG45803.1 - 6.5e-25 88.3 0.1 8e-25 87.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMG45803.1 - 1.3e-19 70.7 0.0 1.7e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMG45803.1 - 3.3e-07 30.1 0.0 5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 EMG45803.1 - 0.039 12.8 0.1 0.41 9.4 0.1 2.2 2 1 0 2 2 2 0 RmlD substrate binding domain UCH PF00443.24 EMG45804.1 - 2.6e-55 187.4 3.6 6.9e-55 186.0 2.5 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMG45804.1 - 6.5e-17 61.9 0.8 6.5e-17 61.9 0.6 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase VID27 PF08553.5 EMG45806.1 - 2.4e-301 1001.7 22.6 2.6e-301 1001.6 15.7 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein DUF2076 PF09849.4 EMG45807.1 - 2.4 8.1 13.4 19 5.1 6.2 2.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF4650 PF15509.1 EMG45807.1 - 9.7 4.9 11.6 0.05 12.5 1.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4650) GLTP PF08718.6 EMG45808.1 - 1.2e-44 151.9 0.1 2e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) DUF3246 PF11596.3 EMG45809.1 - 2.3e-30 105.6 111.3 3.4e-30 105.1 55.7 12.3 5 3 5 10 10 10 6 Protein of unknown function (DUF3246) Frag1 PF10277.4 EMG45810.1 - 1.5e-54 184.7 21.4 1.8e-54 184.4 14.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF962 PF06127.6 EMG45810.1 - 0.064 13.1 4.1 0.097 12.5 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF962) SDF PF00375.13 EMG45810.1 - 0.16 10.6 5.7 0.017 13.8 0.9 1.6 2 0 0 2 2 2 0 Sodium:dicarboxylate symporter family Cation_ATPase_C PF00689.16 EMG45810.1 - 2.3 7.7 17.9 0.25 10.8 5.8 2.2 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus RRM_1 PF00076.17 EMG45811.1 - 3.2e-27 93.9 2.3 6.3e-13 48.1 0.1 4.2 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG45811.1 - 3.3e-19 68.6 0.2 1.1e-08 34.9 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG45811.1 - 1.8e-17 62.8 0.3 1.2e-06 28.2 0.1 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pox_P35 PF03213.9 EMG45811.1 - 0.04 12.9 0.6 0.067 12.1 0.4 1.3 1 0 0 1 1 1 0 Poxvirus P35 protein Nup35_RRM_2 PF14605.1 EMG45811.1 - 0.057 13.2 0.1 0.65 9.8 0.0 2.7 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif DUF148 PF02520.12 EMG45812.1 - 0.0016 18.2 0.6 6 6.7 0.0 3.7 2 2 2 4 4 4 2 Domain of unknown function DUF148 Baculo_PEP_C PF04513.7 EMG45812.1 - 0.016 14.9 7.6 0.098 12.4 5.3 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Perilipin PF03036.11 EMG45812.1 - 0.42 9.4 2.3 1.9 7.2 0.2 2.2 1 1 1 2 2 2 0 Perilipin family DUF1542 PF07564.6 EMG45812.1 - 1.1 9.3 5.4 15 5.6 0.9 3.2 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1542) Flo11 PF10182.4 EMG45813.1 - 6.6e-17 61.4 0.2 1.5e-16 60.3 0.1 1.5 1 0 0 1 1 1 1 Flo11 domain Adaptin_N PF01602.15 EMG45814.1 - 8.5e-89 298.2 6.0 1.1e-88 297.8 4.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EMG45814.1 - 1.9e-10 40.8 2.3 3.5e-07 30.4 0.1 4.5 3 2 2 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 EMG45814.1 - 0.00018 21.9 0.4 1.4 9.5 0.1 4.1 2 1 2 4 4 4 1 HEAT-like repeat HEAT PF02985.17 EMG45814.1 - 0.00022 21.0 0.1 24 5.3 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.2 EMG45814.1 - 0.014 15.2 2.8 8.2 6.2 0.0 3.8 3 2 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Daxx PF03344.10 EMG45814.1 - 2.5 6.5 18.8 4.1 5.7 13.1 1.2 1 0 0 1 1 1 0 Daxx Family XPG_N PF00752.12 EMG45815.1 - 1.1e-35 121.9 0.0 3.7e-35 120.2 0.0 2.0 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EMG45815.1 - 2.9e-27 94.5 0.1 1.2e-26 92.5 0.0 2.2 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EMG45815.1 - 0.0014 18.8 0.0 0.0014 18.8 0.0 3.4 3 1 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.11 EMG45815.1 - 0.0029 17.6 0.0 0.0058 16.7 0.0 1.5 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family JmjC PF02373.17 EMG45816.1 - 2.1e-39 134.2 1.7 6.3e-39 132.7 1.2 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 EMG45816.1 - 9.7e-16 57.0 1.9 1.9e-15 56.0 1.3 1.5 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.1 EMG45816.1 - 6.6e-14 51.8 9.3 6.6e-14 51.8 6.4 2.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EMG45816.1 - 8.8e-13 48.2 4.8 8.8e-13 48.2 3.3 2.0 3 0 0 3 3 3 1 PHD-zinc-finger like domain Rad17 PF03215.10 EMG45817.1 - 2.1e-20 72.9 2.6 3.2e-20 72.3 1.8 1.2 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EMG45817.1 - 0.0011 19.7 0.0 0.0023 18.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMG45817.1 - 0.0023 18.0 0.0 0.0093 16.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EMG45817.1 - 0.0028 17.9 0.1 0.0031 17.7 0.1 1.5 1 1 0 1 1 1 1 ABC transporter RNA_helicase PF00910.17 EMG45817.1 - 0.0038 17.3 0.0 0.0077 16.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.1 EMG45817.1 - 0.0057 16.6 0.1 0.016 15.2 0.1 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.24 EMG45817.1 - 0.017 15.3 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMG45817.1 - 0.017 14.8 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EMG45817.1 - 0.018 14.9 0.1 0.045 13.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EMG45817.1 - 0.022 15.0 0.5 0.13 12.5 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_10 PF12846.2 EMG45817.1 - 0.022 14.2 0.0 0.036 13.5 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.7 EMG45817.1 - 0.054 12.5 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.1 EMG45817.1 - 0.073 12.6 0.1 0.18 11.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Hyphal_reg_CWP PF11765.3 EMG45818.1 - 1.5e-63 214.5 5.4 2.1e-63 214.1 3.7 1.1 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal DSS1_SEM1 PF05160.8 EMG45819.1 - 5e-20 71.0 23.1 6e-20 70.7 16.0 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family AAA PF00004.24 EMG45820.1 - 6.7e-41 139.5 0.0 1.2e-40 138.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMG45820.1 - 4.7e-05 23.4 2.2 0.0095 15.9 0.0 3.2 3 1 1 4 4 4 1 AAA ATPase domain AAA_2 PF07724.9 EMG45820.1 - 8e-05 22.6 0.0 0.00022 21.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EMG45820.1 - 0.00045 19.3 0.1 0.0012 17.9 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EMG45820.1 - 0.00068 19.7 0.3 0.024 14.7 0.2 2.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMG45820.1 - 0.0016 18.2 1.0 0.0066 16.1 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EMG45820.1 - 0.0022 17.8 0.0 0.0056 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EMG45820.1 - 0.0087 15.0 0.1 0.019 13.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.11 EMG45820.1 - 0.0098 15.1 0.1 0.034 13.3 0.1 1.9 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 EMG45820.1 - 0.014 14.5 0.2 0.038 13.1 0.1 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EMG45820.1 - 0.016 14.9 0.2 0.044 13.5 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EMG45820.1 - 0.019 14.4 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 EMG45820.1 - 0.035 14.9 0.3 0.15 12.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EMG45820.1 - 0.039 13.3 1.3 0.3 10.4 0.2 2.3 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.1 EMG45820.1 - 0.058 13.3 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EMG45820.1 - 0.078 12.5 0.5 0.19 11.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain dCMP_cyt_deam_1 PF00383.17 EMG45821.1 - 5.5e-13 48.4 0.0 7.1e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EMG45821.1 - 3.4e-08 33.5 0.3 8e-06 25.8 0.0 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EMG45821.1 - 2e-05 24.0 0.4 0.0068 15.8 0.0 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Ctr PF04145.10 EMG45823.1 - 1.5e-37 128.8 5.1 1.8e-37 128.5 3.5 1.1 1 0 0 1 1 1 1 Ctr copper transporter family MMS1_N PF10433.4 EMG45823.1 - 0.11 10.6 0.0 0.12 10.4 0.0 1.1 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF3021 PF11457.3 EMG45823.1 - 2.1 8.2 12.5 1.8 8.4 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) Transp_cyt_pur PF02133.10 EMG45824.1 - 3.4e-45 154.4 25.3 4.1e-45 154.1 17.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin GST_N_3 PF13417.1 EMG45825.1 - 8.8e-14 51.5 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMG45825.1 - 2e-11 43.7 0.1 3.2e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMG45825.1 - 2.4e-11 43.4 0.0 4.8e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMG45825.1 - 2.5e-10 40.3 0.0 5.1e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMG45825.1 - 2.1e-08 33.9 0.0 3.6e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMG45825.1 - 1.3e-07 32.0 0.2 2e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EMG45825.1 - 0.012 16.0 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 MetRS-N binding domain SBF PF01758.11 EMG45826.1 - 1.4e-49 168.0 15.9 1.4e-49 168.0 11.0 2.0 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF2663 PF10864.3 EMG45826.1 - 0.2 11.8 3.4 0.77 9.9 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2663) DUF3464 PF11947.3 EMG45826.1 - 0.97 8.8 5.6 0.12 11.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) UQ_con PF00179.21 EMG45827.1 - 0.028 13.8 1.1 0.36 10.2 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme ABC_membrane_2 PF06472.10 EMG45827.1 - 0.035 13.2 0.2 0.07 12.2 0.0 1.5 2 0 0 2 2 2 0 ABC transporter transmembrane region 2 Clathrin PF00637.15 EMG45827.1 - 0.038 13.6 0.2 0.038 13.6 0.1 2.4 3 0 0 3 3 3 0 Region in Clathrin and VPS RWD PF05773.17 EMG45827.1 - 9.3 6.1 13.2 25 4.7 9.2 1.8 1 1 0 1 1 1 0 RWD domain PseudoU_synth_2 PF00849.17 EMG45828.1 - 6.5e-15 55.3 0.0 8.5e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF3759 PF12585.3 EMG45829.1 - 2.6e-33 113.7 2.9 3e-33 113.5 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) AAA-ATPase_like PF09820.4 EMG45829.1 - 0.051 12.7 0.0 0.053 12.6 0.0 1.0 1 0 0 1 1 1 0 Predicted AAA-ATPase DPRP PF04244.8 EMG45829.1 - 0.092 12.2 0.1 0.1 12.0 0.1 1.1 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein DUF2114 PF09887.4 EMG45829.1 - 0.12 10.6 0.0 0.38 9.0 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) Zip PF02535.17 EMG45830.1 - 3.2e-35 121.6 27.3 5.7e-34 117.5 18.9 2.2 1 1 0 1 1 1 1 ZIP Zinc transporter HupE_UreJ PF04955.7 EMG45830.1 - 0.00079 18.7 5.2 0.00079 18.7 3.6 2.4 2 0 0 2 2 2 2 HupE / UreJ protein HRXXH PF13933.1 EMG45831.1 - 4.2e-102 340.7 2.2 5.4e-102 340.4 1.5 1.1 1 0 0 1 1 1 1 Putative peptidase family Nop14 PF04147.7 EMG45831.1 - 0.0033 15.4 14.0 0.0041 15.1 9.7 1.1 1 0 0 1 1 1 1 Nop14-like family HCV_NS5a_1a PF08300.8 EMG45831.1 - 0.033 14.1 0.8 0.11 12.4 0.6 1.9 1 1 0 1 1 1 0 Hepatitis C virus non-structural 5a zinc finger domain Pox_Ag35 PF03286.9 EMG45831.1 - 0.036 13.5 4.4 0.066 12.7 3.1 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Zip PF02535.17 EMG45831.1 - 0.22 10.5 10.7 0.29 10.0 7.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter VID27 PF08553.5 EMG45831.1 - 1.7 6.7 9.6 2.2 6.4 6.7 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF1510 PF07423.6 EMG45831.1 - 2.2 7.5 12.4 3.4 6.9 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 EMG45831.1 - 5.7 4.8 14.8 8.5 4.2 10.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Prothymosin PF03247.9 EMG45831.1 - 6.1 7.0 25.6 11 6.2 17.7 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family LicD PF04991.8 EMG45832.1 - 8.9e-42 143.5 1.4 7.9e-41 140.4 1.0 2.5 1 1 0 1 1 1 1 LicD family ABC2_membrane PF01061.19 EMG45833.1 - 4.5e-31 107.6 29.0 6.7e-31 107.0 20.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EMG45833.1 - 3.7e-26 92.0 0.1 5.6e-26 91.4 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EMG45833.1 - 6.8e-10 39.3 0.4 4.2e-08 33.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 EMG45833.1 - 1.9e-09 37.1 0.6 1.2e-08 34.5 0.4 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EMG45833.1 - 4.8e-06 25.9 0.2 1.1e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EMG45833.1 - 1.5e-05 24.2 0.3 0.16 10.9 0.1 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_25 PF13481.1 EMG45833.1 - 5.4e-05 22.6 0.2 0.0025 17.2 0.1 2.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EMG45833.1 - 5.5e-05 22.4 0.1 5.5e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 EMG45833.1 - 0.0002 21.7 0.1 0.00038 20.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMG45833.1 - 0.00032 21.4 0.0 0.00084 20.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMG45833.1 - 0.0012 18.8 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMG45833.1 - 0.0021 18.2 0.1 0.011 15.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EMG45833.1 - 0.003 16.6 26.0 0.003 16.6 18.0 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein MMR_HSR1 PF01926.18 EMG45833.1 - 0.0035 17.3 0.3 0.0084 16.0 0.2 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.1 EMG45833.1 - 0.0064 16.7 0.1 0.018 15.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA PF00004.24 EMG45833.1 - 0.0073 16.5 0.2 0.25 11.5 0.2 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EMG45833.1 - 0.0083 15.5 0.2 0.025 14.0 0.2 1.7 2 0 0 2 2 2 1 AAA-like domain AAA_33 PF13671.1 EMG45833.1 - 0.024 14.4 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EMG45833.1 - 0.027 14.4 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EMG45833.1 - 0.027 13.9 0.1 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family cobW PF02492.14 EMG45833.1 - 0.051 13.0 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain HK PF02110.10 EMG45833.1 - 0.051 12.7 0.1 3.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family SbcCD_C PF13558.1 EMG45833.1 - 0.059 13.2 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.10 EMG45833.1 - 0.068 11.8 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein ABC_ATPase PF09818.4 EMG45833.1 - 0.07 11.7 0.1 0.12 10.9 0.1 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class NACHT PF05729.7 EMG45833.1 - 0.14 11.8 0.1 0.39 10.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.18 EMG45833.1 - 0.19 11.5 1.2 0.44 10.3 0.9 1.7 1 1 0 1 1 1 0 Dynamin family Aminotran_3 PF00202.16 EMG45834.1 - 2.3e-104 348.9 0.0 3e-104 348.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EMG45834.1 - 0.014 14.4 0.0 0.027 13.4 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EMG45834.1 - 0.036 13.2 0.0 0.087 11.9 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase NUC129 PF08157.6 EMG45835.1 - 0.13 12.1 0.6 0.92 9.4 0.3 2.1 1 1 1 2 2 2 0 NUC129 domain Metallophos PF00149.23 EMG45836.1 - 1.6e-40 138.6 0.6 1.6e-40 138.6 0.4 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Img2 PF05046.9 EMG45837.1 - 2.2e-19 69.4 0.4 3e-19 69.0 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Pox_Rif PF03340.8 EMG45837.1 - 0.011 13.8 0.1 0.011 13.7 0.1 1.0 1 0 0 1 1 1 0 Poxvirus rifampicin resistance protein BON PF04972.12 EMG45837.1 - 0.039 13.6 0.2 0.087 12.5 0.1 1.6 1 0 0 1 1 1 0 BON domain UPF0086 PF01868.11 EMG45837.1 - 0.11 12.0 0.4 0.25 11.0 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function UPF0086 Pkinase PF00069.20 EMG45838.1 - 1.3e-66 224.4 0.0 2.6e-66 223.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG45838.1 - 1.1e-37 129.5 0.1 3.9e-36 124.4 0.1 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG45838.1 - 1.2e-05 24.3 0.3 0.00017 20.6 0.1 2.6 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EMG45838.1 - 0.0082 15.8 0.2 0.025 14.3 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EMG45838.1 - 0.059 12.4 0.0 0.37 9.8 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 EMG45839.1 - 7.9e-84 272.8 31.7 5.9e-14 51.3 0.0 8.6 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 EMG45839.1 - 1.6e-06 28.0 0.8 0.088 12.5 0.0 4.3 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EMG45839.1 - 1.6e-05 23.2 13.1 0.051 11.7 0.1 5.0 4 2 2 6 6 6 3 Nucleoporin Nup120/160 Hira PF07569.6 EMG45839.1 - 0.007 15.6 0.8 1.3 8.2 0.1 3.1 3 0 0 3 3 3 1 TUP1-like enhancer of split Gmad1 PF10647.4 EMG45839.1 - 0.016 14.6 0.9 0.28 10.5 0.1 2.3 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 EMG45839.1 - 2.9 7.6 7.5 68 3.2 0.0 5.3 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat F-box-like PF12937.2 EMG45840.1 - 0.058 13.1 0.4 0.14 11.8 0.3 1.7 1 0 0 1 1 1 0 F-box-like RNA12 PF10443.4 EMG45840.1 - 0.071 11.5 0.2 0.2 10.1 0.0 1.7 2 0 0 2 2 2 0 RNA12 protein FNIP PF05725.7 EMG45840.1 - 0.24 11.3 28.4 8.4 6.4 0.0 9.1 9 2 1 10 10 10 0 FNIP Repeat LRR_8 PF13855.1 EMG45840.1 - 1.3 8.7 45.1 0.41 10.4 2.8 9.5 7 4 2 10 10 10 0 Leucine rich repeat SKG6 PF08693.5 EMG45841.1 - 2.5e-12 45.8 0.0 4e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MFS_1 PF07690.11 EMG45842.1 - 9.3e-31 106.8 36.6 2.3e-30 105.5 25.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2542 PF10808.3 EMG45842.1 - 0.09 13.0 4.3 0.14 12.3 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2542) Fmp27 PF10344.4 EMG45844.1 - 6.9e-158 526.9 57.8 1.4e-157 526.0 40.1 1.5 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Fmp27_WPPW PF10359.4 EMG45844.1 - 2.1e-141 471.6 11.1 6.3e-141 470.0 7.7 1.9 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.4 EMG45844.1 - 1.6e-102 343.7 13.4 1.6e-102 343.7 9.3 3.6 4 1 0 4 4 4 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.4 EMG45844.1 - 1.1e-53 181.3 0.0 5e-53 179.1 0.0 2.3 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EMG45844.1 - 3.3e-49 166.6 1.6 3.3e-49 166.6 1.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EMG45844.1 - 1.9e-26 92.4 0.2 2.1e-25 89.0 0.2 3.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain RabGAP-TBC PF00566.13 EMG45845.1 - 4.8e-50 169.9 0.7 1.5e-49 168.3 0.5 1.9 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 EMG45845.1 - 4.1e-09 35.8 0.3 1.2e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 GRAM domain EF-hand_7 PF13499.1 EMG45845.1 - 1.2e-05 25.3 2.3 6.1e-05 23.0 0.3 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EMG45845.1 - 0.00013 21.5 2.0 0.45 10.5 0.2 3.6 3 0 0 3 3 3 2 EF-hand domain Vps36_ESCRT-II PF11605.3 EMG45845.1 - 0.0005 19.8 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 EF-hand_1 PF00036.27 EMG45845.1 - 0.0011 18.0 3.1 0.25 10.7 0.0 3.4 3 0 0 3 3 3 2 EF hand DUF1770 PF08589.5 EMG45847.1 - 9e-05 23.0 0.3 0.00016 22.1 0.0 1.5 1 1 1 2 2 2 1 Fungal protein of unknown function (DUF1770) RNA_pol_A_bac PF01000.21 EMG45848.1 - 5.5e-31 107.0 0.0 8.8e-31 106.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EMG45848.1 - 2.4e-14 52.2 0.0 3.1e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain His_biosynth PF00977.16 EMG45849.1 - 3.2e-13 49.4 0.0 4.7e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein PcrB PF01884.12 EMG45849.1 - 0.0038 16.4 0.0 0.06 12.5 0.0 2.1 2 0 0 2 2 2 1 PcrB family Ribul_P_3_epim PF00834.14 EMG45849.1 - 0.077 12.0 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Aldolase PF01081.14 EMG45849.1 - 0.086 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 KDPG and KHG aldolase DUF4502 PF14950.1 EMG45850.1 - 0.01 15.0 6.9 0.02 14.0 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) FlgN PF05130.7 EMG45850.1 - 0.14 12.4 3.1 0.62 10.3 2.2 2.0 1 1 0 1 1 1 0 FlgN protein Ribosomal_S30 PF04758.9 EMG45850.1 - 1.3 8.8 6.0 0.99 9.2 0.3 2.9 3 0 0 3 3 3 0 Ribosomal protein S30 Cnd2 PF05786.9 EMG45851.1 - 1.9e-118 396.9 36.9 2.5e-118 396.6 25.6 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 Rad21_Rec8_N PF04825.8 EMG45851.1 - 0.077 12.9 0.2 0.41 10.6 0.0 2.4 3 0 0 3 3 3 0 N terminus of Rad21 / Rec8 like protein Glyco_hydro_16 PF00722.16 EMG45852.1 - 8e-47 158.9 0.9 1.7e-46 157.8 0.6 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Herpes_BLLF1 PF05109.8 EMG45852.1 - 0.19 9.6 33.1 0.22 9.4 23.0 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) HCO3_cotransp PF00955.16 EMG45853.1 - 2.9e-61 207.7 14.2 4.8e-38 131.0 5.3 2.1 1 1 1 2 2 2 2 HCO3- transporter family Asparaginase_2 PF01112.13 EMG45854.1 - 5.7e-21 74.5 0.0 3.3e-15 55.6 0.0 2.1 2 0 0 2 2 2 2 Asparaginase Ribosomal_L24e PF01246.15 EMG45855.1 - 4e-34 116.2 0.3 4e-34 116.2 0.2 2.1 2 1 0 2 2 2 1 Ribosomal protein L24e Ribosomal_L7Ae PF01248.21 EMG45856.1 - 7.1e-25 86.3 0.0 8e-25 86.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DASH_Spc34 PF08657.5 EMG45857.1 - 1.4e-32 113.3 11.1 2.1e-32 112.8 7.7 1.2 1 0 0 1 1 1 1 DASH complex subunit Spc34 LemA PF04011.7 EMG45857.1 - 5.4e-05 22.3 0.7 9.8e-05 21.5 0.5 1.4 1 0 0 1 1 1 1 LemA family DMPK_coil PF08826.5 EMG45857.1 - 0.0088 15.9 0.4 0.032 14.1 0.3 1.9 1 0 0 1 1 1 1 DMPK coiled coil domain like PAH PF02671.16 EMG45857.1 - 0.017 14.7 1.1 0.078 12.6 0.0 2.5 3 0 0 3 3 3 0 Paired amphipathic helix repeat Mod_r PF07200.8 EMG45857.1 - 0.035 14.0 1.6 0.074 12.9 0.4 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein IncA PF04156.9 EMG45857.1 - 0.058 12.9 0.6 0.085 12.4 0.4 1.4 1 0 0 1 1 1 0 IncA protein DUF4482 PF14818.1 EMG45857.1 - 0.15 12.7 1.3 0.61 10.7 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4482) Med9 PF07544.8 EMG45857.1 - 0.19 11.4 7.4 7.9 6.2 0.1 3.8 2 2 2 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Prefoldin_2 PF01920.15 EMG45857.1 - 0.19 11.4 4.3 0.16 11.7 0.3 2.5 2 1 0 2 2 2 0 Prefoldin subunit Pox_A_type_inc PF04508.7 EMG45857.1 - 5.5 7.0 7.0 1.6 8.7 0.1 3.3 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Peptidase_M22 PF00814.20 EMG45858.1 - 3e-84 282.6 0.0 3.6e-84 282.4 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family BcrAD_BadFG PF01869.15 EMG45858.1 - 0.096 11.9 0.2 2.2 7.5 0.0 2.1 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Staygreen PF12638.2 EMG45858.1 - 0.1 12.1 0.0 0.98 8.9 0.0 2.2 2 0 0 2 2 2 0 Staygreen protein DnaJ PF00226.26 EMG45859.1 - 9e-20 70.1 1.7 1.7e-19 69.2 0.5 2.0 2 0 0 2 2 2 1 DnaJ domain RRM_6 PF14259.1 EMG45859.1 - 6.6e-08 32.4 0.0 2.2e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMG45859.1 - 4.3e-06 26.2 0.1 1.3e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG45859.1 - 3.5e-05 23.5 0.0 8.5e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.1 EMG45859.1 - 0.0098 15.4 0.1 0.021 14.3 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4523) LAGLIDADG_1 PF00961.14 EMG45859.1 - 2.8 8.5 9.1 0.64 10.6 0.1 3.2 3 1 0 3 3 3 0 LAGLIDADG endonuclease DUF543 PF04418.7 EMG45860.1 - 4e-30 103.5 0.1 4.7e-30 103.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Acatn PF13000.2 EMG45861.1 - 5.2e-162 540.1 23.9 2.2e-106 356.6 8.1 2.3 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 SNF2_N PF00176.18 EMG45862.1 - 2.7e-61 206.9 0.1 7.1e-61 205.6 0.1 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMG45862.1 - 7.3e-12 44.9 0.0 2.8e-11 43.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMG45862.1 - 1.5e-08 34.3 0.1 5.5e-07 29.2 0.0 2.8 2 1 1 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 EMG45862.1 - 3.8e-06 26.8 0.1 1.6e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PAT1 PF09770.4 EMG45862.1 - 1.2 7.2 19.0 1.7 6.8 13.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UCR_UQCRX_QCR9 PF05365.7 EMG45863.1 - 8.7e-20 70.1 3.1 9.8e-20 69.9 2.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like SBDS_C PF09377.5 EMG45864.1 - 3.6e-39 133.3 3.8 5.6e-39 132.6 2.7 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EMG45864.1 - 3.1e-30 103.8 2.8 7.5e-30 102.5 2.0 1.7 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein XkdN PF08890.6 EMG45864.1 - 0.0046 16.6 1.0 0.012 15.4 0.1 2.1 1 1 1 2 2 2 1 Phage XkdN-like protein DnaJ PF00226.26 EMG45865.1 - 3.4e-18 65.1 0.1 3.4e-18 65.1 0.1 2.7 3 0 0 3 3 3 1 DnaJ domain Spc24 PF08286.6 EMG45865.1 - 0.088 12.5 0.2 0.088 12.5 0.1 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 IPP-2 PF04979.9 EMG45866.1 - 1.6e-07 31.6 25.0 6.2e-07 29.7 12.1 3.0 1 1 1 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) eIF3_subunit PF08597.5 EMG45866.1 - 0.35 10.4 14.9 0.13 11.8 3.8 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Myc_N PF01056.13 EMG45866.1 - 1.3 8.1 7.0 0.092 11.8 1.4 1.6 2 0 0 2 2 2 0 Myc amino-terminal region CENP-T PF15511.1 EMG45866.1 - 1.9 7.6 13.5 2.3 7.3 9.3 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T WD40 PF00400.27 EMG45867.1 - 1.1e-56 186.7 18.0 7.6e-07 28.7 0.0 11.4 13 0 0 13 13 13 8 WD domain, G-beta repeat Pyrid_oxidase_2 PF13883.1 EMG45868.1 - 1.5e-50 171.2 0.0 2.2e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Med20 PF08612.6 EMG45868.1 - 1.1e-41 142.4 0.0 1.4e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex FlbD PF06289.6 EMG45868.1 - 0.081 12.3 0.1 0.32 10.4 0.0 2.0 2 0 0 2 2 2 0 Flagellar protein (FlbD) GvpL_GvpF PF06386.6 EMG45868.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF MutS_V PF00488.16 EMG45869.1 - 1.8e-43 148.6 0.0 3e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EMG45869.1 - 2.3e-25 89.5 0.8 3.3e-25 89.0 0.2 1.5 2 0 0 2 2 2 1 MutS domain III AAA_29 PF13555.1 EMG45869.1 - 0.0099 15.3 0.0 0.022 14.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.1 EMG45869.1 - 0.027 14.3 1.0 0.11 12.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EMG45869.1 - 0.07 13.2 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EMG45869.1 - 0.079 11.8 0.3 0.36 9.6 0.0 2.1 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_23 PF13476.1 EMG45869.1 - 0.084 13.1 0.0 0.084 13.1 0.0 2.9 2 1 0 2 2 2 0 AAA domain DEAD PF00270.24 EMG45870.1 - 1e-44 152.0 0.1 2e-44 151.0 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EMG45870.1 - 1.2e-22 79.2 0.1 3.3e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EMG45870.1 - 4e-18 65.0 0.0 9.9e-18 63.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EMG45870.1 - 0.0003 20.7 0.0 0.00085 19.3 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain Arm PF00514.18 EMG45871.1 - 1.8e-75 246.4 26.1 7.7e-12 44.5 0.0 11.1 12 0 0 12 12 12 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMG45871.1 - 1.6e-24 85.9 9.1 2.6e-08 34.0 0.1 7.5 1 1 5 8 8 8 5 HEAT repeats HEAT_EZ PF13513.1 EMG45871.1 - 1.3e-19 70.0 14.2 1.5e-06 28.4 0.4 8.7 8 1 1 9 9 9 5 HEAT-like repeat HEAT PF02985.17 EMG45871.1 - 9.5e-17 59.5 24.8 0.0046 16.9 0.0 10.1 11 1 0 11 11 11 4 HEAT repeat Adaptin_N PF01602.15 EMG45871.1 - 2.1e-14 52.7 5.0 2.5e-08 32.7 0.8 2.3 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.7 EMG45871.1 - 1e-10 40.2 0.2 2.7e-10 38.8 0.1 1.8 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) Arm_2 PF04826.8 EMG45871.1 - 2.5e-10 39.9 6.5 0.00072 18.7 0.2 3.5 2 1 1 3 3 3 3 Armadillo-like Vac14_Fab1_bd PF12755.2 EMG45871.1 - 7.4e-06 26.2 0.1 0.12 12.8 0.0 3.1 2 1 0 2 2 2 2 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.3 EMG45871.1 - 0.00091 19.1 2.0 0.87 9.5 0.1 4.4 1 1 4 5 5 5 1 V-ATPase subunit H DUF2454 PF10521.4 EMG45871.1 - 0.0011 18.0 0.2 2 7.3 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF2454) Syntaxin PF00804.20 EMG45871.1 - 0.01 16.0 0.4 0.026 14.6 0.3 1.7 1 0 0 1 1 1 0 Syntaxin RIX1 PF08167.7 EMG45871.1 - 0.019 14.6 0.4 0.41 10.3 0.0 3.1 1 1 2 3 3 3 0 rRNA processing/ribosome biogenesis Snf7 PF03357.16 EMG45872.1 - 4.2e-15 55.5 21.3 7.1e-15 54.8 14.7 1.3 1 0 0 1 1 1 1 Snf7 FBA_2 PF07735.12 EMG45872.1 - 0.0029 17.4 0.3 0.0029 17.4 0.2 2.8 3 0 0 3 3 3 1 F-box associated Enkurin PF13864.1 EMG45872.1 - 0.046 13.9 1.0 0.046 13.9 0.7 2.6 1 1 0 2 2 2 0 Calmodulin-binding SGL PF08450.7 EMG45873.1 - 7.5e-77 258.0 0.3 8.9e-77 257.7 0.2 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region D123 PF07065.9 EMG45874.1 - 9.7e-100 333.4 8.8 1.1e-99 333.2 6.1 1.0 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 EMG45874.1 - 0.084 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) Aha1_N PF09229.6 EMG45874.1 - 0.3 10.9 3.2 0.22 11.3 0.2 2.1 2 0 0 2 2 2 0 Activator of Hsp90 ATPase, N-terminal Cpn60_TCP1 PF00118.19 EMG45875.1 - 1.2e-138 462.8 15.2 1.5e-138 462.4 10.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sas10 PF09368.5 EMG45876.1 - 4.1e-30 103.7 11.9 4.1e-30 103.7 8.2 2.1 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EMG45876.1 - 2e-09 37.4 2.6 2.9e-09 36.9 0.2 2.5 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Methyltransf_12 PF08242.7 EMG45876.1 - 0.13 12.7 2.1 0.78 10.2 1.5 2.4 1 1 0 1 1 1 0 Methyltransferase domain RNA_pol_Rpc4 PF05132.9 EMG45877.1 - 2.4e-24 85.7 0.4 2.4e-24 85.7 0.3 3.2 2 2 0 2 2 2 1 RNA polymerase III RPC4 SLX9 PF15341.1 EMG45877.1 - 0.043 14.2 1.1 0.076 13.4 0.8 1.4 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF3373 PF11853.3 EMG45877.1 - 0.079 11.4 0.2 0.093 11.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF964 PF06133.6 EMG45878.1 - 0.15 12.0 3.3 0.96 9.4 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF964) Alpha_GJ PF03229.8 EMG45878.1 - 4.3 7.6 8.3 9.3 6.6 5.7 1.5 1 0 0 1 1 1 0 Alphavirus glycoprotein J Aldedh PF00171.17 EMG45879.1 - 3.2e-128 427.9 0.0 3.7e-128 427.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family hDGE_amylase PF14701.1 EMG45880.1 - 5.7e-167 555.9 1.4 9e-167 555.2 1.0 1.3 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EMG45880.1 - 5.2e-119 397.2 0.0 9.9e-119 396.3 0.0 1.5 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EMG45880.1 - 3.2e-73 246.1 0.0 5.2e-73 245.4 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EMG45880.1 - 8e-25 86.4 2.3 1.8e-24 85.3 1.6 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 EMG45880.1 - 9e-06 25.2 0.7 0.0056 16.1 0.2 2.6 2 0 0 2 2 2 2 Alpha amylase, catalytic domain F-box PF00646.28 EMG45881.1 - 0.1 12.2 0.7 0.29 10.8 0.5 1.8 1 0 0 1 1 1 0 F-box domain LRR_4 PF12799.2 EMG45884.1 - 0.0013 18.2 0.8 0.0049 16.4 0.5 2.0 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG45884.1 - 0.0014 18.3 0.2 0.0029 17.3 0.1 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_6 PF13516.1 EMG45884.1 - 0.0026 17.6 0.5 0.019 14.9 0.1 2.3 2 0 0 2 2 2 1 Leucine Rich repeat LRR_1 PF00560.28 EMG45884.1 - 0.016 15.1 2.2 0.13 12.3 0.1 2.6 2 1 0 2 2 2 0 Leucine Rich Repeat LRR_7 PF13504.1 EMG45884.1 - 0.084 13.1 0.5 0.92 9.9 0.1 2.5 2 0 0 2 2 2 0 Leucine rich repeat Glyco_hydro_18 PF00704.23 EMG45885.1 - 8.1e-24 84.6 0.3 1e-22 81.0 0.1 2.2 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 Flocculin_t3 PF13928.1 EMG45885.1 - 1.9e-13 50.2 21.7 1.9e-13 50.2 15.1 6.3 4 3 1 5 5 5 1 Flocculin type 3 repeat Daxx PF03344.10 EMG45885.1 - 0.0015 17.1 21.6 0.002 16.7 15.0 1.1 1 0 0 1 1 1 1 Daxx Family PLRV_ORF5 PF01690.12 EMG45885.1 - 0.45 9.5 19.8 0.63 9.1 13.7 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Mitofilin PF09731.4 EMG45885.1 - 2.9 6.4 22.3 3.9 5.9 15.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TFIIF_alpha PF05793.7 EMG45885.1 - 8.3 4.6 31.8 11 4.2 22.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Amidase PF01425.16 EMG45886.1 - 1.7e-85 287.5 0.0 2.4e-85 287.0 0.0 1.2 1 0 0 1 1 1 1 Amidase Linker_histone PF00538.14 EMG45887.1 - 1e-19 70.3 0.4 2.3e-19 69.2 0.3 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family Hid1 PF12722.2 EMG45887.1 - 1.2 6.7 8.2 1.3 6.5 5.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DNA_pol_viral_N PF00242.12 EMG45887.1 - 3.4 6.6 11.2 4 6.3 7.8 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain FMO-like PF00743.14 EMG45888.1 - 2.1e-28 98.8 1.3 1.6e-15 56.3 0.6 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EMG45888.1 - 3.5e-26 92.5 0.0 6.9e-25 88.3 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMG45888.1 - 1.4e-09 38.1 0.0 1.7e-06 28.0 0.0 3.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMG45888.1 - 3.2e-09 36.7 0.1 1.6e-06 27.9 0.1 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EMG45888.1 - 2.5e-06 26.6 0.0 0.00036 19.5 0.0 3.2 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EMG45888.1 - 3.3e-06 27.0 0.0 1e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMG45888.1 - 0.00075 18.6 0.1 0.24 10.4 0.0 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 EMG45888.1 - 0.013 14.4 0.0 0.042 12.7 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMG45888.1 - 0.051 13.9 0.6 2.7 8.4 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EMG45888.1 - 0.11 12.8 0.0 6 7.1 0.0 2.4 2 1 0 2 2 2 0 Putative NAD(P)-binding LRR_4 PF12799.2 EMG45889.1 - 0.00024 20.6 0.4 0.00024 20.6 0.3 7.9 6 4 0 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG45889.1 - 0.00031 20.4 1.2 0.00031 20.4 0.8 6.6 6 2 1 7 7 7 2 Leucine rich repeat LRR_7 PF13504.1 EMG45889.1 - 0.0052 16.7 10.5 16 6.2 0.0 7.8 8 0 0 8 8 8 1 Leucine rich repeat LRR_1 PF00560.28 EMG45889.1 - 1.1 9.5 19.2 6.7 7.1 0.1 7.4 8 0 0 8 8 8 0 Leucine Rich Repeat LRR_6 PF13516.1 EMG45889.1 - 3.9 7.8 7.2 1.2e+02 3.2 0.4 5.9 7 0 0 7 7 7 0 Leucine Rich repeat NUP PF06516.6 EMG45890.1 - 4.6e-05 22.3 0.1 5.2e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) RINGv PF12906.2 EMG45891.1 - 4.9e-17 61.7 10.2 7.8e-17 61.0 7.1 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EMG45891.1 - 0.013 15.3 9.2 0.024 14.4 6.4 1.5 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.3 EMG45891.1 - 0.068 13.1 6.0 0.15 12.0 4.2 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EMG45891.1 - 5.6 6.6 7.4 9.9 5.8 5.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EMG45891.1 - 6.3 6.9 8.9 25 5.0 6.3 1.9 1 1 1 2 2 2 0 RING-H2 zinc finger TFIID-18kDa PF02269.11 EMG45892.1 - 2.1e-17 62.6 0.4 3.5e-17 61.9 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EMG45892.1 - 3.7e-06 26.5 0.1 8.1e-06 25.4 0.1 1.5 1 1 0 1 1 1 1 Bromodomain associated CENP-S PF15630.1 EMG45892.1 - 0.008 16.3 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Rrn6 PF10214.4 EMG45892.1 - 0.024 12.7 2.4 0.038 12.1 1.7 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor VID27 PF08553.5 EMG45892.1 - 0.51 8.4 9.3 0.68 8.0 6.4 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein CDC45 PF02724.9 EMG45892.1 - 0.73 7.8 8.7 0.88 7.5 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein p450 PF00067.17 EMG45893.1 - 1.9e-49 168.4 0.0 2.6e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Redoxin PF08534.5 EMG45894.1 - 3.4e-24 85.0 0.0 3.9e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EMG45894.1 - 0.00036 20.2 0.0 0.00052 19.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Glutaredoxin PF00462.19 EMG45896.1 - 1.4e-17 63.4 0.0 2e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.9 EMG45896.1 - 0.00034 20.8 0.0 0.00048 20.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.1 EMG45896.1 - 0.00062 19.5 0.1 0.0013 18.5 0.0 1.6 1 1 1 2 2 2 1 Thioredoxin domain GST_N_3 PF13417.1 EMG45896.1 - 0.001 19.2 0.0 0.0015 18.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DSBA PF01323.15 EMG45896.1 - 0.0016 18.0 0.1 0.32 10.5 0.0 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_9 PF14595.1 EMG45896.1 - 0.0079 15.7 0.0 0.0099 15.4 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.1 EMG45896.1 - 0.01 15.8 0.9 0.69 9.8 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin GST_N_2 PF13409.1 EMG45896.1 - 0.021 14.7 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin PF00085.15 EMG45896.1 - 0.022 14.4 0.1 0.023 14.3 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin TF_Zn_Ribbon PF08271.7 EMG45896.1 - 0.081 12.2 0.1 0.15 11.3 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding RNA_lig_T4_1 PF09511.5 EMG45897.1 - 2.3e-79 265.9 0.3 4.8e-79 264.9 0.2 1.6 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 EMG45897.1 - 5.5e-64 215.0 2.8 1.6e-63 213.5 2.0 1.8 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 EMG45897.1 - 1.9e-49 168.2 0.4 3.8e-49 167.2 0.3 1.5 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain ABC_tran PF00005.22 EMG45897.1 - 0.067 13.4 0.4 4.3 7.6 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Exo70 PF03081.10 EMG45898.1 - 1.1e-79 267.8 12.8 1.1e-79 267.8 8.9 2.1 2 0 0 2 2 2 2 Exo70 exocyst complex subunit MCPsignal PF00015.16 EMG45898.1 - 0.025 14.1 1.2 0.36 10.3 0.1 2.4 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.6 EMG45898.1 - 0.54 10.1 4.9 1.7 8.5 0.7 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) MutL_C PF08676.6 EMG45899.1 - 4.6e-30 104.1 0.0 2e-29 102.0 0.0 2.0 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 EMG45899.1 - 1.5e-26 92.1 0.1 2.9e-26 91.2 0.1 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EMG45899.1 - 1.6e-13 50.4 0.4 4.6e-13 48.9 0.3 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EMG45899.1 - 2.8e-12 46.3 1.6 4.1e-12 45.8 0.2 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glutaredoxin PF00462.19 EMG45900.1 - 1.8e-20 72.6 0.0 2.7e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.1 EMG45900.1 - 3.5e-05 23.3 0.0 4.3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EMG45900.1 - 0.0016 18.0 0.1 0.27 10.7 0.0 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain DUF836 PF05768.9 EMG45900.1 - 0.0035 17.5 0.0 0.0059 16.8 0.0 1.5 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.1 EMG45900.1 - 0.004 17.1 2.0 0.4 10.6 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.1 EMG45900.1 - 0.013 15.2 0.4 0.047 13.5 0.3 2.0 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin_2 PF13098.1 EMG45900.1 - 0.018 15.2 0.2 0.037 14.2 0.2 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain AAA_23 PF13476.1 EMG45901.1 - 1.7e-16 61.1 10.9 1.7e-16 61.1 7.6 6.2 2 2 1 3 3 3 1 AAA domain SMC_N PF02463.14 EMG45901.1 - 4e-16 58.9 39.1 1.3e-15 57.2 27.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Reo_sigmaC PF04582.7 EMG45901.1 - 0.00074 18.7 21.0 0.1 11.7 0.3 4.6 4 1 1 5 5 5 3 Reovirus sigma C capsid protein AAA_21 PF13304.1 EMG45901.1 - 0.0065 16.4 10.0 0.0065 16.4 6.9 5.0 2 2 1 4 4 4 2 AAA domain AAA_29 PF13555.1 EMG45901.1 - 0.0098 15.4 0.1 0.023 14.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Myosin_tail_1 PF01576.14 EMG45901.1 - 0.063 11.0 80.1 0.026 12.2 16.9 4.0 3 1 0 3 3 3 0 Myosin tail ABC_tran PF00005.22 EMG45901.1 - 0.087 13.1 0.1 0.087 13.1 0.1 5.2 3 2 1 4 4 4 0 ABC transporter AAA_13 PF13166.1 EMG45901.1 - 0.094 11.1 91.1 0.6 8.4 0.1 5.7 3 2 1 5 5 5 0 AAA domain IncA PF04156.9 EMG45901.1 - 0.13 11.8 77.1 0.043 13.4 14.0 6.0 2 2 2 5 5 5 0 IncA protein 60KD_IMP PF02096.15 EMG45902.1 - 8.3e-42 143.0 5.4 8.3e-42 143.0 3.7 1.6 1 1 1 2 2 2 1 60Kd inner membrane protein DUF3135 PF11333.3 EMG45902.1 - 3.4 7.8 6.4 0.82 9.8 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3135) Epimerase PF01370.16 EMG45903.1 - 1.6e-19 70.2 0.3 3.5e-19 69.1 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMG45903.1 - 5.5e-13 48.2 0.0 8.1e-13 47.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMG45903.1 - 1.2e-09 38.4 0.0 1.5e-08 34.8 0.0 2.4 1 1 1 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMG45903.1 - 9.9e-08 31.2 0.3 4.4e-06 25.8 0.1 2.7 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.20 EMG45903.1 - 3.6e-06 27.0 0.0 6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EMG45903.1 - 0.00013 21.2 2.2 0.00062 19.0 1.5 2.2 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EMG45903.1 - 0.00016 20.7 0.2 0.0019 17.1 0.6 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 EMG45903.1 - 0.01 15.5 0.1 0.025 14.2 0.0 1.7 1 1 0 1 1 1 0 KR domain Pro_isomerase PF00160.16 EMG45904.1 - 1.2e-46 158.7 0.3 1.4e-46 158.5 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LRR_4 PF12799.2 EMG45905.1 - 9.9e-11 41.0 28.0 0.00013 21.4 0.0 7.4 8 2 0 8 8 8 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG45905.1 - 6.7e-08 32.1 32.2 0.00017 21.2 0.5 7.1 6 1 1 8 8 8 4 Leucine rich repeat LRR_1 PF00560.28 EMG45905.1 - 0.0074 16.1 25.2 0.2 11.8 0.1 9.1 8 2 0 8 8 8 2 Leucine Rich Repeat LRRNT PF01462.13 EMG45905.1 - 0.22 11.0 1.2 2.1 7.9 0.0 2.6 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain RasGEF PF00617.14 EMG45906.1 - 2.7e-38 131.5 2.8 2.4e-35 121.9 0.2 3.1 3 0 0 3 3 3 2 RasGEF domain RhoGAP PF00620.22 EMG45906.1 - 3.9e-37 127.1 0.0 1.3e-36 125.4 0.0 2.0 1 0 0 1 1 1 1 RhoGAP domain RasGEF_N PF00618.15 EMG45906.1 - 1.9e-17 63.2 0.8 2.3e-16 59.7 0.6 3.1 1 0 0 1 1 1 1 RasGEF N-terminal motif PH_9 PF15410.1 EMG45906.1 - 0.014 15.5 0.2 1.3 9.2 0.0 3.0 2 0 0 2 2 2 0 Pleckstrin homology domain Dpoe2NT PF12213.3 EMG45906.1 - 0.042 13.7 0.9 0.21 11.5 0.2 2.5 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal DUF2457 PF10446.4 EMG45907.1 - 3.5e-05 22.7 15.9 4.9e-05 22.2 11.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) RNA_pol_3_Rpc31 PF11705.3 EMG45907.1 - 0.06 13.2 19.2 0.11 12.4 13.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 alpha-hel2 PF14456.1 EMG45907.1 - 0.09 11.5 3.3 0.11 11.2 2.3 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 SDA1 PF05285.7 EMG45907.1 - 0.092 12.0 8.0 0.1 11.8 5.6 1.2 1 0 0 1 1 1 0 SDA1 CobT PF06213.7 EMG45907.1 - 0.2 10.7 13.8 0.25 10.4 9.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Astro_capsid PF03115.9 EMG45907.1 - 0.27 9.4 1.8 0.29 9.3 1.2 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Daxx PF03344.10 EMG45907.1 - 0.29 9.5 12.3 0.35 9.2 8.5 1.2 1 0 0 1 1 1 0 Daxx Family Paf1 PF03985.8 EMG45907.1 - 0.38 9.4 8.8 0.44 9.2 6.1 1.2 1 0 0 1 1 1 0 Paf1 RRN3 PF05327.6 EMG45907.1 - 0.42 8.6 3.4 0.45 8.5 2.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 EMG45907.1 - 0.53 8.2 10.1 0.67 7.9 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.8 EMG45907.1 - 0.71 9.7 15.4 0.085 12.7 7.8 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit VID27 PF08553.5 EMG45907.1 - 1.2 7.3 10.8 1.4 7.0 7.5 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Cwf_Cwc_15 PF04889.7 EMG45907.1 - 1.3 8.7 10.7 1.8 8.2 7.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TRAP_alpha PF03896.11 EMG45907.1 - 2.1 7.2 8.7 2.9 6.8 6.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit p450 PF00067.17 EMG45908.1 - 2.6e-50 171.2 0.0 3.6e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3114 PF11311.3 EMG45908.1 - 0.061 12.6 0.2 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) NifU_N PF01592.11 EMG45909.1 - 2.9e-55 185.6 0.1 3.5e-55 185.3 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Ribosomal_L18p PF00861.17 EMG45911.1 - 3e-44 150.0 2.3 3.1e-44 149.9 0.0 1.9 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EMG45911.1 - 4.8e-33 113.5 7.4 4.8e-33 113.5 5.1 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 EMG45911.1 - 0.0083 16.1 1.0 0.36 10.8 0.2 2.9 2 1 0 2 2 2 1 Threonine synthase N terminus DUF1160 PF06648.6 EMG45911.1 - 0.047 13.4 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) MFS_1 PF07690.11 EMG45912.1 - 2.3e-33 115.3 35.5 2.3e-33 115.3 24.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG45912.1 - 4e-14 52.0 11.8 4e-14 52.0 8.2 2.7 2 2 0 2 2 2 1 Sugar (and other) transporter DUF21 PF01595.15 EMG45912.1 - 4.6 6.4 7.9 1 8.6 1.0 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF21 HAMP PF00672.20 EMG45913.1 - 8.6e-39 131.5 15.5 1.2e-09 38.2 0.1 6.1 5 1 1 6 6 6 5 HAMP domain HATPase_c PF02518.21 EMG45913.1 - 1.6e-29 101.8 0.3 4.9e-29 100.2 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMG45913.1 - 6.4e-26 90.5 0.6 1.2e-24 86.5 0.1 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EMG45913.1 - 4.1e-19 68.3 3.8 3.4e-18 65.3 0.4 3.5 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain IL32 PF15225.1 EMG45913.1 - 0.0094 15.8 0.4 43 4.1 0.0 3.6 3 0 0 3 3 3 0 Interleukin 32 DUF2365 PF10157.4 EMG45913.1 - 1.2 9.0 17.1 8.5 6.2 0.1 6.3 4 1 1 6 6 6 0 Uncharacterized conserved protein (DUF2365) Aminotran_3 PF00202.16 EMG45914.1 - 2.4e-102 342.2 0.0 2.7e-102 342.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EMG45914.1 - 0.0001 21.5 0.0 0.00015 21.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase AAA_26 PF13500.1 EMG45915.1 - 4.1e-51 173.4 0.0 6.7e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AA_permease_2 PF13520.1 EMG45915.1 - 5.6e-46 156.9 55.9 7.2e-46 156.5 38.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMG45915.1 - 1.3e-13 50.1 47.5 1.7e-13 49.7 32.9 1.1 1 0 0 1 1 1 1 Amino acid permease CbiA PF01656.18 EMG45915.1 - 0.026 13.9 1.1 0.34 10.2 0.7 2.2 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF218 PF02698.12 EMG45915.1 - 0.048 13.1 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 DUF218 domain Chitin_synth_1 PF01644.12 EMG45916.1 - 6.5e-84 279.6 1.4 1.1e-83 278.9 1.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 EMG45916.1 - 4.7e-26 91.2 4.0 4.9e-21 74.7 0.0 2.6 3 0 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.6 EMG45916.1 - 5.4e-26 90.0 0.1 1.7e-25 88.5 0.1 1.9 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 EMG45916.1 - 8e-10 38.7 1.5 8e-10 38.7 1.1 2.6 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMG45916.1 - 2.3e-07 30.8 0.0 6.3e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF805 PF05656.9 EMG45916.1 - 0.0031 17.3 4.2 0.0031 17.3 2.9 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF805) RCC1 PF00415.13 EMG45917.1 - 1.6e-63 210.7 0.0 9.3e-13 48.1 0.0 7.4 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMG45917.1 - 6.8e-38 127.4 19.1 3.3e-07 29.7 0.1 6.6 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat DNA_pol_B PF00136.16 EMG45918.1 - 3.1e-147 491.1 4.0 4.3e-147 490.6 2.7 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EMG45918.1 - 1.8e-89 299.7 1.6 3.7e-89 298.8 0.8 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EMG45918.1 - 4.6e-25 87.4 3.4 1.1e-24 86.2 2.4 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 EMG45918.1 - 0.0036 17.1 0.6 0.012 15.3 0.1 2.3 2 1 0 2 2 2 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 EMG45918.1 - 0.0053 16.3 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB HD_2 PF12917.2 EMG45918.1 - 0.043 13.5 0.6 0.11 12.2 0.4 1.7 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme C1_1 PF00130.17 EMG45918.1 - 1.7 8.4 6.9 8.9 6.1 0.4 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) D-ser_dehydrat PF14031.1 EMG45919.1 - 3e-21 75.4 0.0 6.4e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EMG45919.1 - 2.2e-13 50.3 0.1 3e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain GST_N PF02798.15 EMG45920.1 - 1.1e-13 51.1 0.0 9.9e-13 48.0 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMG45920.1 - 2.7e-11 43.5 0.0 4.5e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMG45920.1 - 8.3e-11 41.7 0.0 1.5e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMG45920.1 - 1.1e-08 34.9 0.0 2.1e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMG45920.1 - 7e-05 22.6 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMG45920.1 - 0.002 18.5 0.0 0.0026 18.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GAS PF13851.1 EMG45921.1 - 0.01 15.0 16.1 0.012 14.7 11.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TSA PF03249.8 EMG45921.1 - 0.023 13.2 0.1 0.026 13.1 0.1 1.1 1 0 0 1 1 1 0 Type specific antigen Pkip-1 PF06878.6 EMG45921.1 - 0.067 13.0 5.7 0.085 12.7 3.9 1.1 1 0 0 1 1 1 0 Pkip-1 protein Allexi_40kDa PF05549.6 EMG45921.1 - 0.26 10.5 5.6 0.31 10.3 3.9 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Sds3 PF08598.6 EMG45921.1 - 1.2 8.6 11.0 1.7 8.1 7.2 1.4 1 1 0 1 1 1 0 Sds3-like DUF724 PF05266.9 EMG45921.1 - 1.6 8.2 12.7 1.9 8.0 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF3987 PF13148.1 EMG45921.1 - 1.8 7.0 7.4 2.2 6.7 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) MCPVI PF02993.9 EMG45921.1 - 4.7 7.3 11.8 5.6 7.0 8.2 1.1 1 0 0 1 1 1 0 Minor capsid protein VI CENP-F_leu_zip PF10473.4 EMG45922.1 - 4.2e-05 23.4 8.8 4.2e-05 23.4 6.1 2.3 1 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin PF00261.15 EMG45922.1 - 0.00023 20.3 14.8 0.11 11.6 0.7 3.0 3 0 0 3 3 3 2 Tropomyosin ALIX_LYPXL_bnd PF13949.1 EMG45922.1 - 0.0009 18.2 2.9 0.0009 18.2 2.0 2.0 1 1 0 2 2 2 1 ALIX V-shaped domain binding to HIV NPV_P10 PF05531.7 EMG45922.1 - 0.0015 18.7 1.9 0.2 11.9 0.2 2.5 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 EMG45922.1 - 0.0025 16.3 10.3 0.003 16.0 7.1 1.0 1 0 0 1 1 1 1 AAA domain COG2 PF06148.6 EMG45922.1 - 0.06 13.2 11.5 1.1 9.1 0.5 2.9 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 MscS_porin PF12795.2 EMG45922.1 - 0.094 12.0 7.6 0.27 10.5 5.3 1.8 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Streptin-Immun PF11083.3 EMG45922.1 - 0.12 12.4 8.1 0.072 13.0 2.2 2.8 1 1 2 3 3 3 0 Lantibiotic streptin immunity protein HrpB7 PF09486.5 EMG45922.1 - 0.15 11.9 2.8 0.37 10.6 1.6 1.9 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Reo_sigmaC PF04582.7 EMG45922.1 - 0.15 11.1 2.7 0.61 9.2 1.9 1.8 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Zein-binding PF04576.10 EMG45922.1 - 0.2 11.8 7.8 0.38 10.9 2.3 3.0 2 1 0 2 2 2 0 Zein-binding Filament PF00038.16 EMG45922.1 - 0.3 10.5 13.9 5 6.5 9.8 2.3 1 1 0 1 1 1 0 Intermediate filament protein DUF3347 PF11827.3 EMG45922.1 - 0.34 10.9 4.4 0.51 10.3 3.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) Fez1 PF06818.10 EMG45922.1 - 0.34 10.8 9.2 0.05 13.6 2.3 2.0 1 1 1 2 2 2 0 Fez1 Bacillus_HBL PF05791.6 EMG45922.1 - 0.39 10.0 7.4 0.17 11.2 2.8 1.9 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Spc7 PF08317.6 EMG45922.1 - 0.4 9.2 15.1 3.6 6.1 10.5 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF948 PF06103.6 EMG45922.1 - 0.54 10.1 4.2 0.29 10.9 0.2 2.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.14 EMG45922.1 - 0.65 7.7 12.8 0.065 11.0 5.1 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Vps51 PF08700.6 EMG45922.1 - 0.67 9.8 11.8 1.5 8.7 1.0 3.1 2 1 1 3 3 3 0 Vps51/Vps67 DUF812 PF05667.6 EMG45922.1 - 0.71 8.3 11.7 1.5 7.2 8.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) IFT57 PF10498.4 EMG45922.1 - 0.79 8.3 13.3 0.25 10.0 4.5 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 LLC1 PF14945.1 EMG45922.1 - 0.8 10.0 3.4 0.6 10.4 0.2 2.2 2 1 1 3 3 3 0 Normal lung function maintenance, Low in Lung Cancer 1 protein BLOC1_2 PF10046.4 EMG45922.1 - 1.5 9.0 7.2 1.6 8.8 1.8 2.9 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 WEMBL PF05701.6 EMG45922.1 - 1.7 7.0 16.2 2.2 6.6 11.2 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Histone_HNS PF00816.16 EMG45922.1 - 1.8 9.1 5.9 4.5 7.8 1.2 2.5 1 1 1 2 2 2 0 H-NS histone family TBPIP PF07106.8 EMG45922.1 - 2.4 7.6 15.0 1.4 8.4 6.0 2.5 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 EMG45922.1 - 2.7 7.5 18.3 0.14 11.7 5.4 2.0 1 1 1 2 2 2 0 IncA protein DUF4446 PF14584.1 EMG45922.1 - 3.1 7.6 8.5 0.57 10.0 0.7 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) CCDC-167 PF15188.1 EMG45922.1 - 3.6 7.6 12.5 6.3 6.8 1.8 2.6 2 2 0 2 2 2 0 Coiled-coil domain-containing protein 167 Laminin_II PF06009.7 EMG45922.1 - 4.2 7.1 10.7 4 7.2 2.8 2.2 1 1 1 2 2 2 0 Laminin Domain II WD40_alt PF14077.1 EMG45922.1 - 4.3 7.0 9.7 5.9 6.6 1.8 2.6 1 1 1 2 2 2 0 Alternative WD40 repeat motif DUF1664 PF07889.7 EMG45922.1 - 4.3 7.1 8.0 10 5.9 1.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.17 EMG45922.1 - 4.5 7.3 13.5 2.7 8.0 5.6 2.5 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 EMG45922.1 - 4.8 6.1 14.8 0.65 8.9 5.5 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Vac_Fusion PF02346.11 EMG45922.1 - 5.3 6.5 8.7 5.6 6.4 1.0 2.5 2 0 0 2 2 2 0 Chordopoxvirus fusion protein TMF_DNA_bd PF12329.3 EMG45922.1 - 9.5 6.1 18.9 3.1 7.6 3.1 2.9 1 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding RNA_pol_Rpb2_2 PF04561.9 EMG45923.1 - 0.064 12.6 2.6 0.092 12.1 1.8 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 DUF2704 PF10866.3 EMG45923.1 - 0.07 12.5 1.1 0.078 12.3 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) FliD_C PF07195.7 EMG45923.1 - 0.094 11.9 9.9 0.18 11.0 6.9 1.5 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus HAUS6_N PF14661.1 EMG45923.1 - 0.15 11.4 13.2 0.44 9.8 9.2 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus RE_AlwI PF09491.5 EMG45923.1 - 0.17 10.2 9.6 0.19 10.1 6.6 1.1 1 0 0 1 1 1 0 AlwI restriction endonuclease DUF3416 PF11896.3 EMG45923.1 - 2.1 8.2 7.7 0.4 10.5 2.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3416) DUF3810 PF12725.2 EMG45923.1 - 3.9 6.2 6.6 1.3 7.8 3.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) V_ATPase_I PF01496.14 EMG45923.1 - 5.7 4.6 10.5 5.9 4.6 7.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 EMG45923.1 - 6.6 5.5 13.4 8.3 5.2 9.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Dynamin_N PF00350.18 EMG45925.1 - 7.2e-40 136.5 0.0 7.2e-40 136.5 0.0 2.4 3 0 0 3 3 3 1 Dynamin family Miro PF08477.8 EMG45925.1 - 0.00055 20.4 0.0 0.0027 18.1 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein Dynamin_M PF01031.15 EMG45925.1 - 0.00062 18.6 0.8 0.00062 18.6 0.5 3.4 3 1 0 3 3 3 2 Dynamin central region MMR_HSR1 PF01926.18 EMG45925.1 - 0.0018 18.1 0.0 0.0085 16.0 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EMG45925.1 - 0.012 15.6 0.2 0.043 13.7 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain DUF4248 PF14053.1 EMG45925.1 - 0.099 12.2 0.1 0.56 9.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) AKAP7_RIRII_bdg PF10470.4 EMG45925.1 - 0.92 9.3 5.0 1.7 8.5 0.0 3.2 3 0 0 3 3 3 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein WD40 PF00400.27 EMG45926.1 - 3.9e-05 23.3 0.2 0.042 13.7 0.0 5.3 6 0 0 6 6 6 1 WD domain, G-beta repeat bPH_4 PF06713.6 EMG45926.1 - 0.023 14.5 0.8 0.1 12.4 0.3 2.3 2 0 0 2 2 2 0 Bacterial PH domain Sfi1 PF08457.5 EMG45927.1 - 1.5e-55 188.7 54.8 7.3e-55 186.4 37.9 1.8 1 1 0 1 1 1 1 Sfi1 spindle body protein Glyco_transf_22 PF03901.12 EMG45928.1 - 8e-38 130.5 13.9 1e-37 130.1 9.7 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family cobW PF02492.14 EMG45929.1 - 2.7e-40 137.7 0.7 3.8e-40 137.2 0.5 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EMG45929.1 - 3.3e-08 33.1 0.0 6.9e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_18 PF13238.1 EMG45929.1 - 0.0016 18.7 0.3 0.004 17.4 0.2 1.7 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EMG45929.1 - 0.0021 18.0 0.8 0.0074 16.2 0.5 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 EMG45929.1 - 0.0057 16.5 0.3 0.031 14.1 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EMG45929.1 - 0.0064 16.0 0.3 0.018 14.5 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EMG45929.1 - 0.023 14.9 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Miro PF08477.8 EMG45929.1 - 0.034 14.6 1.1 1 9.8 0.0 2.9 2 1 1 3 3 3 0 Miro-like protein AAA_16 PF13191.1 EMG45929.1 - 0.042 13.8 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EMG45929.1 - 0.049 13.7 0.0 0.099 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EMG45929.1 - 0.087 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 EMG45929.1 - 0.092 13.0 3.6 0.3 11.3 2.5 1.8 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EMG45929.1 - 0.21 12.4 1.6 0.46 11.3 0.3 2.3 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 EMG45929.1 - 1.4 8.3 4.0 24 4.3 2.8 2.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Tim54 PF11711.3 EMG45930.1 - 7.7e-138 459.2 3.1 1.5e-137 458.2 2.1 1.4 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DASH_Duo1 PF08651.5 EMG45931.1 - 7.3e-13 47.9 2.2 7.3e-13 47.9 1.5 1.9 2 0 0 2 2 2 1 DASH complex subunit Duo1 DASH_Dad2 PF08654.5 EMG45931.1 - 0.0036 17.2 2.1 0.014 15.3 1.0 1.9 1 1 1 2 2 2 1 DASH complex subunit Dad2 Orbi_NS3 PF01616.11 EMG45931.1 - 0.034 13.1 0.1 0.062 12.2 0.0 1.4 1 0 0 1 1 1 0 Orbivirus NS3 Laminin_II PF06009.7 EMG45931.1 - 0.036 13.8 3.7 2.5 7.8 0.3 2.1 2 0 0 2 2 2 0 Laminin Domain II KIAA1430 PF13879.1 EMG45931.1 - 0.061 13.7 8.3 0.35 11.3 1.9 2.1 2 0 0 2 2 2 0 KIAA1430 homologue DUF2450 PF10475.4 EMG45931.1 - 0.073 11.9 1.2 0.14 11.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) Retrotrans_gag PF03732.12 EMG45931.1 - 0.076 13.0 0.3 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 Retrotransposon gag protein bZIP_1 PF00170.16 EMG45931.1 - 0.13 12.2 5.3 2.8 7.9 1.6 2.3 2 0 0 2 2 2 0 bZIP transcription factor DASH_Dad1 PF08649.5 EMG45931.1 - 0.13 11.9 2.2 0.14 11.9 0.2 1.9 2 0 0 2 2 2 0 DASH complex subunit Dad1 Baculo_PEP_C PF04513.7 EMG45931.1 - 0.15 11.8 6.2 2.6 7.8 1.8 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.4 EMG45931.1 - 0.46 10.6 5.8 0.54 10.4 0.4 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 EMG45931.1 - 1.1 9.4 4.0 0.77 10.0 0.2 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Med31 PF05669.7 EMG45932.1 - 2.8e-42 142.6 4.5 3.8e-42 142.2 3.1 1.1 1 0 0 1 1 1 1 SOH1 Acetyltransf_6 PF13480.1 EMG45933.1 - 3.1e-08 33.6 0.0 7.2e-08 32.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FAD_binding_1 PF00667.15 EMG45933.1 - 0.033 13.6 2.4 0.062 12.7 1.6 1.4 1 0 0 1 1 1 0 FAD binding domain Oxidored_q2 PF00420.19 EMG45933.1 - 0.15 11.7 12.8 12 5.5 8.9 2.8 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L OEP PF02321.13 EMG45934.1 - 0.015 14.9 1.0 0.015 14.9 0.7 1.6 2 0 0 2 2 2 0 Outer membrane efflux protein Nup88 PF10168.4 EMG45934.1 - 0.057 11.2 3.4 0.072 10.9 2.3 1.1 1 0 0 1 1 1 0 Nuclear pore component PEHE PF15275.1 EMG45934.1 - 3.2 8.2 12.1 4.3 7.8 0.1 2.9 3 0 0 3 3 3 0 PEHE domain Peptidase_M20 PF01546.23 EMG45935.1 - 4.4e-24 85.0 0.0 6.2e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMG45935.1 - 4.9e-08 32.7 0.0 1.6e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EMG45935.1 - 0.0024 17.6 0.0 0.0067 16.1 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 Pkinase PF00069.20 EMG45936.1 - 5.7e-69 232.1 0.1 1.4e-68 230.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG45936.1 - 5.3e-47 160.0 0.0 8.8e-47 159.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG45936.1 - 1.5e-05 24.1 0.0 0.0012 17.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EMG45936.1 - 0.072 12.1 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAM_1 PF00536.25 EMG45936.1 - 0.16 12.1 0.7 0.42 10.8 0.2 1.9 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) TctB PF07331.6 EMG45937.1 - 0.0021 17.7 1.2 0.0024 17.5 0.8 1.1 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family GlpM PF06942.7 EMG45937.1 - 0.004 17.3 0.1 0.0044 17.2 0.0 1.1 1 0 0 1 1 1 1 GlpM protein MASE1 PF05231.9 EMG45937.1 - 0.043 12.8 0.1 0.046 12.7 0.0 1.0 1 0 0 1 1 1 0 MASE1 Spore_YtrH PF14034.1 EMG45937.1 - 0.11 12.4 0.2 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Sporulation protein YtrH RRN9 PF10680.4 EMG45938.1 - 2.7e-14 52.6 1.7 2.7e-14 52.6 1.2 2.0 2 1 0 2 2 2 1 RNA polymerase I specific transcription initiation factor CLTH PF10607.4 EMG45939.1 - 7e-31 106.8 10.0 7e-31 106.8 6.9 2.5 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EMG45939.1 - 3.9e-06 26.4 0.1 9.7e-06 25.1 0.0 1.7 1 0 0 1 1 1 1 LisH PH_3 PF14593.1 EMG45939.1 - 0.0047 16.8 0.2 0.014 15.2 0.0 1.9 2 0 0 2 2 2 1 PH domain FAM176 PF14851.1 EMG45939.1 - 5.4 6.6 10.3 0.63 9.7 3.3 2.0 1 1 1 2 2 2 0 FAM176 family PMT PF02366.13 EMG45940.1 - 8.4e-78 261.1 24.3 8.4e-78 261.1 16.8 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EMG45940.1 - 4.9e-25 88.1 0.6 7.6e-25 87.5 0.4 1.3 1 0 0 1 1 1 1 MIR domain FAD_binding_8 PF08022.7 EMG45941.1 - 1.4e-23 82.7 0.0 2.6e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EMG45941.1 - 1.5e-21 76.7 9.8 1.5e-21 76.7 6.8 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component Ribosomal_L10 PF00466.15 EMG45942.1 - 2e-05 24.4 0.0 3.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Methyltransf_4 PF02390.12 EMG45943.1 - 4.3e-60 202.1 0.0 6e-60 201.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EMG45943.1 - 6.8e-05 23.4 0.0 0.00011 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMG45943.1 - 7.5e-05 22.3 0.0 0.00015 21.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMG45943.1 - 0.0042 16.4 0.0 0.032 13.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EMG45943.1 - 0.03 14.7 0.1 0.093 13.2 0.0 1.9 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_26 PF13659.1 EMG45943.1 - 0.092 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EMG45943.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EMG45943.1 - 0.12 12.0 0.0 0.31 10.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Reticulon PF02453.12 EMG45944.1 - 5.5e-39 133.4 4.7 8.6e-39 132.8 3.2 1.3 1 0 0 1 1 1 1 Reticulon SID-1_RNA_chan PF13965.1 EMG45946.1 - 0.017 13.2 0.1 0.017 13.2 0.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 7TM_GPCR_Srw PF10324.4 EMG45946.1 - 0.017 14.2 0.1 0.018 14.1 0.0 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Sdh_cyt PF01127.17 EMG45946.1 - 0.024 14.4 0.1 0.026 14.3 0.0 1.1 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4492 PF14899.1 EMG45946.1 - 0.052 13.0 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) DmsC PF04976.7 EMG45946.1 - 0.078 12.2 0.1 0.089 12.0 0.1 1.1 1 0 0 1 1 1 0 DMSO reductase anchor subunit (DmsC) DUF843 PF05814.6 EMG45946.1 - 0.091 12.5 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) ATP-synt_8 PF00895.15 EMG45946.1 - 0.14 12.4 0.2 0.14 12.4 0.1 1.6 2 0 0 2 2 2 0 ATP synthase protein 8 Asp PF00026.18 EMG45947.1 - 8.2e-61 205.9 4.7 1.3e-60 205.3 3.2 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMG45947.1 - 8.2e-09 35.6 0.1 1.1e-06 28.6 0.0 2.8 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMG45947.1 - 0.00018 21.9 5.9 0.2 12.1 0.1 3.7 4 0 0 4 4 4 2 Aspartyl protease TAXi_C PF14541.1 EMG45947.1 - 0.02 14.4 0.1 0.2 11.1 0.0 2.4 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EMG45947.1 - 0.039 13.7 0.4 0.21 11.4 0.0 2.2 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 EMG45947.1 - 0.05 13.5 0.2 0.72 9.8 0.0 2.7 3 0 0 3 3 3 0 Retroviral aspartyl protease AAA_11 PF13086.1 EMG45949.1 - 0.0098 15.4 0.8 0.024 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMG45949.1 - 0.053 13.2 0.2 0.095 12.4 0.1 1.4 1 0 0 1 1 1 0 Part of AAA domain POTRA_2 PF08479.6 EMG45949.1 - 0.12 12.0 0.1 20 4.9 0.0 2.4 2 0 0 2 2 2 0 POTRA domain, ShlB-type Aconitase PF00330.15 EMG45950.1 - 4.6e-74 249.5 0.1 2.4e-46 158.2 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EMG45950.1 - 2.7e-28 98.6 0.0 5.9e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 EMG45950.1 - 0.02 13.4 0.0 0.035 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Pkinase PF00069.20 EMG45951.1 - 1.5e-69 234.0 0.0 8.6e-69 231.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG45951.1 - 1.1e-32 113.1 0.0 4.9e-31 107.7 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EMG45951.1 - 3.6e-19 67.9 0.3 2.2e-18 65.3 0.0 2.1 2 0 0 2 2 2 1 Kinase associated domain 1 Kdo PF06293.9 EMG45951.1 - 2.5e-06 26.6 0.0 4.9e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMG45951.1 - 0.00012 21.1 0.0 0.00022 20.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMG45951.1 - 0.0054 16.4 0.2 0.069 12.8 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.6 EMG45951.1 - 0.039 13.1 0.1 0.083 12.0 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 EMG45951.1 - 0.38 10.0 2.7 0.37 10.0 0.2 2.3 2 1 0 2 2 2 0 PhoP regulatory network protein YrbL F1F0-ATPsyn_F PF10791.4 EMG45952.1 - 1.5e-40 137.3 0.2 2.2e-40 136.7 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi LSM PF01423.17 EMG45952.1 - 1.1e-17 63.3 0.9 1.4e-17 62.9 0.6 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EMG45952.1 - 0.0018 18.1 0.0 0.0054 16.6 0.1 1.7 2 0 0 2 2 2 1 Ataxin 2 SM domain WRW PF10206.4 EMG45952.1 - 0.0056 16.7 0.0 0.0096 15.9 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f p450 PF00067.17 EMG45953.1 - 3.3e-64 217.1 0.0 4.4e-64 216.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3414 PF11894.3 EMG45954.1 - 0 1584.7 61.5 0 1584.5 42.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) PEPCK_ATP PF01293.15 EMG45955.1 - 3.6e-217 721.4 0.0 4.2e-217 721.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 EMG45955.1 - 0.033 14.0 0.0 0.073 12.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EMG45955.1 - 0.14 11.5 0.0 0.34 10.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain p450 PF00067.17 EMG45956.1 - 1.8e-63 214.6 0.0 2.5e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_3 PF00933.16 EMG45957.1 - 3.2e-48 164.2 0.0 4.7e-48 163.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 EMG45957.1 - 0.039 13.9 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Fungal_trans PF04082.13 EMG45958.1 - 2.3e-21 75.8 0.2 3.8e-21 75.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG45958.1 - 1.2e-06 28.3 5.6 1.2e-06 28.3 3.9 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_18 PF00704.23 EMG45959.1 - 5.9e-21 75.2 3.1 7.7e-19 68.3 1.4 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 XPG_I PF00867.13 EMG45960.1 - 2.2e-25 88.5 0.7 1.2e-24 86.1 0.0 2.5 3 0 0 3 3 3 1 XPG I-region XPG_N PF00752.12 EMG45960.1 - 0.00012 22.2 0.0 0.00033 20.8 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain PAT1 PF09770.4 EMG45962.1 - 1.4 7.0 43.7 1.9 6.6 30.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Aminotran_1_2 PF00155.16 EMG45963.1 - 1.6e-43 149.0 0.0 1.9e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EMG45963.1 - 3.4e-06 26.0 0.0 1.2e-05 24.1 0.0 1.8 1 1 1 2 2 2 1 Aminotransferase class-V Alliinase_C PF04864.8 EMG45963.1 - 1.6e-05 23.7 0.0 2.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Allinase Beta_elim_lyase PF01212.16 EMG45963.1 - 3.2e-05 23.2 0.0 4.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EMG45963.1 - 0.0014 17.0 0.0 0.0019 16.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.2 EMG45963.1 - 0.015 13.8 0.0 0.022 13.3 0.0 1.4 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase FTHFS PF01268.14 EMG45964.1 - 1.1e-247 822.5 0.4 1.4e-247 822.2 0.3 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EMG45964.1 - 2.1e-67 225.2 3.8 2.9e-67 224.7 0.7 2.4 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EMG45964.1 - 6.3e-33 113.2 1.9 4e-32 110.7 1.3 2.3 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.10 EMG45964.1 - 0.0056 15.4 0.3 0.0095 14.7 0.2 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family AdoHcyase_NAD PF00670.16 EMG45964.1 - 0.019 14.7 1.4 0.91 9.3 1.0 2.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_10 PF13460.1 EMG45965.1 - 1.2e-25 90.5 0.8 1.5e-25 90.2 0.6 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMG45965.1 - 6e-11 42.0 4.9 2.2e-09 36.9 3.4 2.0 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EMG45965.1 - 3e-10 39.9 0.2 4.6e-10 39.3 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EMG45965.1 - 5.6e-07 29.8 0.3 1e-06 29.0 0.2 1.5 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EMG45965.1 - 2e-06 26.7 0.6 2.8e-06 26.2 0.4 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EMG45965.1 - 1.1e-05 25.3 0.3 2e-05 24.4 0.2 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 EMG45965.1 - 1.4e-05 24.2 0.3 1.9e-05 23.8 0.2 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 EMG45965.1 - 0.00014 20.9 0.0 0.0044 15.9 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein Ldh_1_N PF00056.18 EMG45965.1 - 0.0021 17.8 0.4 0.0051 16.6 0.3 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 EMG45965.1 - 0.0062 15.4 0.1 0.068 12.0 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain DXP_reductoisom PF02670.11 EMG45965.1 - 0.026 15.0 1.0 0.038 14.5 0.7 1.4 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase adh_short PF00106.20 EMG45965.1 - 0.03 14.2 2.0 0.08 12.8 1.4 1.7 1 1 0 1 1 1 0 short chain dehydrogenase EPL1 PF10513.4 EMG45966.1 - 6.3e-32 111.0 21.8 1.8e-31 109.5 3.5 2.6 2 0 0 2 2 2 2 Enhancer of polycomb-like Colicin-DNase PF12639.2 EMG45966.1 - 0.048 13.9 0.1 0.048 13.9 0.1 3.4 3 0 0 3 3 3 0 DNase/tRNase domain of colicin-like bacteriocin WD40 PF00400.27 EMG45967.1 - 2.2e-09 36.8 0.1 1e-05 25.2 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Pkinase PF00069.20 EMG45968.1 - 7.1e-64 215.4 1.5 1.1e-63 214.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG45968.1 - 2.7e-28 98.7 0.7 5.8e-28 97.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase PAT1 PF09770.4 EMG45968.1 - 0.0031 15.8 14.0 0.0041 15.4 9.7 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 APH PF01636.18 EMG45968.1 - 0.082 12.6 3.4 0.2 11.3 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Hpr_kinase_C PF07475.7 EMG45968.1 - 0.26 10.5 1.2 0.45 9.8 0.9 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain DUF4557 PF15101.1 EMG45968.1 - 0.33 10.7 11.1 0.67 9.7 7.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FH2 PF02181.18 EMG45969.1 - 1.3e-53 182.2 35.0 5.8e-38 130.7 1.9 4.4 3 1 1 4 4 4 3 Formin Homology 2 Domain Drf_GBD PF06371.8 EMG45969.1 - 7.3e-20 71.1 7.4 5.3e-18 65.0 0.5 4.7 5 0 0 5 5 5 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EMG45969.1 - 5.8e-14 51.9 17.6 2.8e-13 49.7 0.5 4.3 4 0 0 4 4 4 2 Diaphanous FH3 Domain PIF1 PF05970.9 EMG45970.1 - 5.4e-50 170.3 5.1 1.9e-46 158.7 3.5 2.9 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EMG45970.1 - 6.2e-16 58.5 0.0 1e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 EMG45970.1 - 1.4e-09 36.3 0.0 2.9e-06 25.3 0.0 2.2 2 0 0 2 2 2 2 Helicase UvrD_C_2 PF13538.1 EMG45970.1 - 1.1e-06 28.6 0.0 0.00014 21.9 0.0 2.8 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 EMG45970.1 - 1.1e-06 28.7 0.3 4.2e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EMG45970.1 - 8.3e-05 21.7 0.0 0.00042 19.3 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 EMG45970.1 - 0.00023 20.1 0.0 0.00045 19.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Viral_helicase1 PF01443.13 EMG45970.1 - 0.00059 19.4 0.4 0.16 11.4 0.0 2.8 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EMG45970.1 - 0.0012 18.5 0.0 0.0038 16.9 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EMG45970.1 - 0.002 18.1 0.2 0.0064 16.4 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EMG45970.1 - 0.0041 17.3 0.1 0.013 15.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EMG45970.1 - 0.011 15.2 0.0 0.085 12.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain TrwB_AAD_bind PF10412.4 EMG45970.1 - 0.017 13.7 0.0 0.03 12.9 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PhoH PF02562.11 EMG45970.1 - 0.017 14.3 0.0 0.051 12.8 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein DEAD PF00270.24 EMG45970.1 - 0.023 14.2 0.2 6.6 6.1 0.0 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_29 PF13555.1 EMG45970.1 - 0.04 13.4 0.0 0.09 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EMG45970.1 - 0.047 13.9 0.1 0.2 11.9 0.1 2.0 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.12 EMG45970.1 - 0.062 12.7 0.0 3.3 7.0 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 EMG45970.1 - 0.63 10.8 4.2 1.2 9.9 0.0 2.9 3 0 0 3 3 2 0 AAA domain Hyphal_reg_CWP PF11765.3 EMG45971.1 - 3.3e-29 101.7 1.6 3.6e-29 101.5 1.1 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal DUF3089 PF11288.3 EMG45976.1 - 0.053 12.6 0.4 0.067 12.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) LRR_8 PF13855.1 EMG45977.1 - 4e-05 23.2 0.6 4e-05 23.2 0.4 8.1 7 2 1 8 8 8 4 Leucine rich repeat LRR_4 PF12799.2 EMG45977.1 - 0.00014 21.4 2.3 0.00014 21.4 1.6 7.8 8 2 1 9 9 9 1 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EMG45977.1 - 9.7 6.9 20.2 3.4 8.2 0.3 7.8 9 2 1 10 10 10 0 Leucine rich repeat DUF3709 PF12493.3 EMG45978.1 - 0.092 12.4 0.3 0.11 12.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3709) Dna2 PF08696.6 EMG45979.1 - 5.6e-34 117.2 1.9 2.4e-33 115.2 1.3 2.2 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_11 PF13086.1 EMG45979.1 - 2.6e-10 40.3 1.6 8.4e-05 22.2 0.0 3.0 2 1 0 3 3 3 2 AAA domain PDDEXK_1 PF12705.2 EMG45979.1 - 1.1e-09 38.0 0.2 2.1e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_30 PF13604.1 EMG45979.1 - 1.9e-07 30.8 0.0 2.9e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 EMG45979.1 - 4.4e-05 23.1 0.5 0.00017 21.2 0.0 2.3 3 0 0 3 3 3 1 Helicase PhoH PF02562.11 EMG45979.1 - 0.00044 19.5 0.1 0.002 17.4 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.1 EMG45979.1 - 0.0015 18.2 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain CbiA PF01656.18 EMG45979.1 - 0.0023 17.3 0.3 0.011 15.1 0.0 2.3 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_14 PF13173.1 EMG45979.1 - 0.003 17.4 3.4 0.053 13.4 0.0 3.8 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EMG45979.1 - 0.031 13.6 0.0 0.09 12.1 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein zf-C2H2 PF00096.21 EMG45980.1 - 5.2e-05 23.3 60.3 0.28 11.6 0.9 10.9 11 0 0 11 11 11 5 Zinc finger, C2H2 type zf-met PF12874.2 EMG45980.1 - 0.004 17.3 14.9 0.07 13.3 0.2 6.1 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EMG45980.1 - 0.086 13.2 52.8 0.51 10.7 0.5 11.1 11 0 0 11 11 11 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMG45980.1 - 1.4 9.1 19.6 3.3 7.9 0.0 6.3 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding His_Phos_1 PF00300.17 EMG45981.1 - 1.6e-30 106.3 0.0 2.1e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) E1-E2_ATPase PF00122.15 EMG45982.1 - 9.9e-71 237.4 2.2 9.9e-71 237.4 1.5 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EMG45982.1 - 1.1e-27 97.8 0.0 4e-26 92.7 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EMG45982.1 - 1.8e-26 92.7 7.3 1.8e-26 92.7 5.1 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 EMG45982.1 - 2.7e-19 68.8 0.0 5.2e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EMG45982.1 - 2e-15 57.4 0.0 4.6e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMG45982.1 - 1.5e-14 53.1 0.0 4e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EMG45982.1 - 0.00058 19.5 0.8 0.0032 17.0 0.7 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AAA_18 PF13238.1 EMG45983.1 - 1.2e-23 83.8 0.1 1.2e-23 83.8 0.1 2.5 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 EMG45983.1 - 1.3e-10 42.1 0.1 1.3e-10 42.1 0.1 2.2 1 1 1 2 2 1 1 AAA domain AAA_16 PF13191.1 EMG45983.1 - 0.0017 18.3 0.2 0.0044 17.0 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 EMG45983.1 - 0.0044 17.1 0.0 0.0089 16.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Viral_helicase1 PF01443.13 EMG45983.1 - 0.0097 15.4 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 EMG45983.1 - 0.015 15.2 0.1 0.98 9.2 0.0 2.6 2 2 0 2 2 2 0 AAA domain KTI12 PF08433.5 EMG45983.1 - 0.016 14.4 0.0 0.016 14.4 0.0 2.0 2 1 0 2 2 2 0 Chromatin associated protein KTI12 AAA_22 PF13401.1 EMG45983.1 - 0.031 14.4 0.0 0.055 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EMG45983.1 - 0.032 14.4 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zot PF05707.7 EMG45983.1 - 0.046 13.1 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) 6PF2K PF01591.13 EMG45983.1 - 0.056 12.5 0.0 0.15 11.0 0.0 1.7 2 0 0 2 2 2 0 6-phosphofructo-2-kinase AAA_28 PF13521.1 EMG45983.1 - 0.057 13.3 0.0 0.057 13.3 0.0 2.3 2 1 0 2 2 1 0 AAA domain Paf1 PF03985.8 EMG45983.1 - 0.074 11.7 16.8 0.093 11.4 11.6 1.2 1 0 0 1 1 1 0 Paf1 PRK PF00485.13 EMG45983.1 - 0.091 12.3 0.8 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_10 PF12846.2 EMG45983.1 - 0.16 11.4 2.8 0.19 11.0 2.0 1.6 1 1 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 EMG45983.1 - 0.17 12.2 0.7 0.27 11.5 0.5 1.7 1 1 0 1 1 1 0 ABC transporter Nop14 PF04147.7 EMG45983.1 - 0.21 9.4 27.2 0.24 9.2 18.9 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 EMG45983.1 - 0.22 10.6 22.7 0.28 10.2 15.7 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DDHD PF02862.12 EMG45983.1 - 0.47 10.2 3.8 0.62 9.8 2.6 1.3 1 0 0 1 1 1 0 DDHD domain Ycf1 PF05758.7 EMG45983.1 - 0.62 7.7 4.7 0.69 7.5 3.2 1.2 1 0 0 1 1 1 0 Ycf1 Vfa1 PF08432.5 EMG45983.1 - 0.68 9.9 12.5 1.2 9.1 8.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NOA36 PF06524.7 EMG45983.1 - 0.71 9.0 12.9 1.1 8.5 9.0 1.3 1 0 0 1 1 1 0 NOA36 protein AAA_11 PF13086.1 EMG45983.1 - 2.9 7.4 9.5 8.5 5.8 6.6 1.8 1 1 0 1 1 1 0 AAA domain Cwf_Cwc_15 PF04889.7 EMG45983.1 - 3.4 7.2 20.9 4.8 6.8 14.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Hpr_kinase_C PF07475.7 EMG45983.1 - 3.9 6.7 7.0 4 6.7 0.0 2.5 3 0 0 3 3 2 0 HPr Serine kinase C-terminal domain SDA1 PF05285.7 EMG45983.1 - 6.1 6.0 25.9 7.7 5.7 18.0 1.2 1 0 0 1 1 1 0 SDA1 Heme_oxygenase PF01126.15 EMG45984.1 - 3.8e-20 72.3 1.6 7.3e-20 71.4 1.1 1.4 1 1 0 1 1 1 1 Heme oxygenase Sugar_tr PF00083.19 EMG45985.1 - 1.9e-77 260.7 22.8 2.2e-77 260.5 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG45985.1 - 3.4e-19 68.7 28.8 5.9e-19 67.9 12.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMG45985.1 - 4.5e-06 25.3 0.7 4.5e-06 25.3 0.5 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 EMG45985.1 - 0.002 16.3 0.3 0.002 16.3 0.2 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Cellulase PF00150.13 EMG45986.1 - 6.2e-30 104.3 1.7 1e-29 103.6 1.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) NatB_MDM20 PF09797.4 EMG45988.1 - 2e-58 197.8 8.8 2e-58 197.8 6.1 1.9 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_16 PF13432.1 EMG45988.1 - 0.032 14.9 0.0 0.092 13.4 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 EMG45988.1 - 0.19 12.0 1.4 0.8 10.0 0.2 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Choline_transpo PF04515.7 EMG45989.1 - 1.9e-99 332.6 24.5 1.9e-99 332.6 17.0 2.1 2 0 0 2 2 2 2 Plasma-membrane choline transporter Renin_r PF07850.9 EMG45989.1 - 3.3 8.1 10.3 17 5.8 0.0 4.4 4 0 0 4 4 4 0 Renin receptor-like protein Metallophos_2 PF12850.2 EMG45990.1 - 4.6e-15 55.7 0.0 7e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Nop14 PF04147.7 EMG45990.1 - 0.04 11.8 13.6 0.049 11.5 9.4 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EMG45990.1 - 0.083 12.1 11.4 0.1 11.8 7.9 1.1 1 0 0 1 1 1 0 SDA1 Pox_Ag35 PF03286.9 EMG45990.1 - 0.17 11.3 9.5 0.25 10.8 6.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF1510 PF07423.6 EMG45990.1 - 0.29 10.4 17.5 0.41 9.9 12.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Trypan_PARP PF05887.6 EMG45990.1 - 0.41 10.4 13.1 0.67 9.7 9.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TRAP_alpha PF03896.11 EMG45990.1 - 0.67 8.9 11.7 0.98 8.3 8.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ycf1 PF05758.7 EMG45990.1 - 1.3 6.6 8.0 1.8 6.1 5.6 1.1 1 0 0 1 1 1 0 Ycf1 Daxx PF03344.10 EMG45990.1 - 2.1 6.7 17.6 2.9 6.2 12.2 1.1 1 0 0 1 1 1 0 Daxx Family Tim54 PF11711.3 EMG45990.1 - 2.3 6.7 7.7 3 6.3 5.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NOA36 PF06524.7 EMG45990.1 - 6.2 5.9 10.0 9 5.4 6.9 1.2 1 0 0 1 1 1 0 NOA36 protein Pox_RNA_Pol_19 PF05320.7 EMG45990.1 - 8.3 6.1 12.6 15 5.3 8.8 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit CDC45 PF02724.9 EMG45990.1 - 8.4 4.2 12.5 11 3.8 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_72 PF03198.9 EMG45991.1 - 3.4e-149 496.0 9.2 5.1e-149 495.4 6.3 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EMG45991.1 - 8.2e-28 96.7 5.2 2.3e-27 95.2 3.6 1.8 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 EMG45991.1 - 1.3e-06 27.8 1.2 1.5e-05 24.3 0.8 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EMG45991.1 - 1.8e-05 23.7 0.3 3.1e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain HMGL-like PF00682.14 EMG45993.1 - 1.4e-70 237.5 0.0 2.1e-70 237.0 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EMG45993.1 - 1.8e-25 89.2 0.3 3.7e-25 88.2 0.2 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Ribosomal_L13 PF00572.13 EMG45994.1 - 1.3e-25 89.9 0.0 2.6e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L13 TipAS PF07739.8 EMG45994.1 - 0.049 13.9 2.0 0.24 11.7 1.8 1.7 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain VWA_N PF08399.6 EMG45995.1 - 0.097 13.2 0.2 0.18 12.4 0.2 1.4 1 0 0 1 1 1 0 VWA N-terminal Gsf2 PF11055.3 EMG45996.1 - 4.7e-146 486.1 0.3 5.6e-146 485.8 0.2 1.0 1 0 0 1 1 1 1 Glucose signalling factor 2 RRM_1 PF00076.17 EMG45997.1 - 5.5e-43 144.4 0.0 6.9e-21 73.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG45997.1 - 2.2e-30 104.4 0.0 2.3e-16 59.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG45997.1 - 1.7e-18 66.2 0.0 1.8e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 EMG45997.1 - 0.1 12.2 0.0 4.6 6.9 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain Kelch_4 PF13418.1 EMG45998.1 - 1.4e-36 123.9 8.2 8.6e-10 38.2 0.0 6.6 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EMG45998.1 - 8.5e-35 118.1 3.4 5.9e-10 39.0 0.0 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EMG45998.1 - 6.8e-34 115.2 14.8 7.6e-09 35.3 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 EMG45998.1 - 1.9e-26 91.1 8.9 2.9e-09 36.7 0.1 6.5 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.20 EMG45998.1 - 2.5e-21 74.9 11.4 8.9e-11 41.1 0.3 5.5 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 EMG45998.1 - 1e-20 72.5 8.3 1.1e-07 31.2 0.0 6.2 6 0 0 6 6 6 4 Kelch motif RAG2 PF03089.9 EMG45998.1 - 0.0016 17.2 0.1 0.038 12.6 0.0 2.9 4 0 0 4 4 4 1 Recombination activating protein 2 TPR_MLP1_2 PF07926.7 EMG45998.1 - 0.004 16.9 11.6 0.004 16.9 8.0 5.8 4 1 3 7 7 7 2 TPR/MLP1/MLP2-like protein Arrestin_N PF00339.24 EMG45999.1 - 6.9e-16 58.3 2.7 1.3e-15 57.5 0.0 2.8 4 0 0 4 4 4 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EMG45999.1 - 1e-08 35.3 3.5 1.3e-05 25.3 0.0 3.5 2 2 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.10 EMG45999.1 - 0.025 13.3 0.1 1.1 7.9 0.0 2.6 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 26 Meth_synt_2 PF01717.13 EMG46000.1 - 0.17 10.8 0.1 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain Cpn60_TCP1 PF00118.19 EMG46001.1 - 2e-139 465.3 13.4 2.3e-139 465.1 9.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.12 EMG46001.1 - 0.016 15.2 0.0 0.085 12.9 0.0 2.2 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor Vps53_N PF04100.7 EMG46002.1 - 1.6e-50 172.0 25.8 3e-46 157.9 15.6 2.7 1 1 1 2 2 2 2 Vps53-like, N-terminal PRAI PF00697.17 EMG46002.1 - 5.3e-22 78.3 0.0 1.8e-21 76.5 0.0 2.0 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase IncA PF04156.9 EMG46002.1 - 0.86 9.1 8.8 1.1 8.8 3.7 2.6 2 0 0 2 2 2 0 IncA protein WD40 PF00400.27 EMG46003.1 - 5.2e-68 222.6 18.7 5e-11 42.0 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EMG46003.1 - 6.2e-31 106.4 10.9 6.2e-31 106.4 7.6 2.3 1 1 1 2 2 1 1 Tup N-terminal Cytochrom_D1 PF02239.11 EMG46003.1 - 0.00012 20.5 0.0 0.13 10.5 0.0 2.3 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 EMG46003.1 - 0.0015 16.7 1.7 0.12 10.5 1.2 3.1 1 1 0 1 1 1 1 Nucleoporin Nup120/160 PD40 PF07676.7 EMG46003.1 - 0.0052 16.4 0.3 52 3.6 0.0 5.0 5 1 0 5 5 5 0 WD40-like Beta Propeller Repeat SPX PF03105.14 EMG46003.1 - 0.016 15.0 9.4 0.023 14.4 6.5 1.2 1 0 0 1 1 1 0 SPX domain Proteasome_A_N PF10584.4 EMG46003.1 - 0.029 13.6 0.2 3.4 7.0 0.0 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature ERM PF00769.14 EMG46003.1 - 0.031 13.8 19.9 0.049 13.1 13.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Exonuc_VII_L PF02601.10 EMG46003.1 - 0.35 10.0 12.3 0.49 9.5 8.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3584 PF12128.3 EMG46003.1 - 1.3 6.2 21.8 1.8 5.8 15.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PAT1 PF09770.4 EMG46003.1 - 3 5.9 50.5 3.9 5.5 35.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BTV_NS2 PF04514.7 EMG46003.1 - 4.9 5.9 14.0 7.2 5.3 9.7 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Neur_chan_memb PF02932.11 EMG46003.1 - 7.6 6.3 7.4 12 5.7 5.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GHMP_kinases_N PF00288.21 EMG46004.1 - 3.2e-10 39.9 0.8 3.2e-10 39.9 0.6 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EMG46004.1 - 0.00098 19.2 0.0 0.0027 17.8 0.0 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal DUF1877 PF08974.5 EMG46004.1 - 0.062 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) HRDC PF00570.18 EMG46004.1 - 0.15 11.7 0.1 6 6.6 0.1 2.3 2 0 0 2 2 2 0 HRDC domain Malic_M PF03949.10 EMG46005.1 - 2.5e-76 256.5 0.0 3.6e-76 256.0 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EMG46005.1 - 1.8e-59 200.4 0.0 4.1e-59 199.2 0.0 1.6 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain YojJ PF10372.4 EMG46005.1 - 0.15 11.9 0.1 0.37 10.6 0.1 1.6 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus AP_endonuc_2 PF01261.19 EMG46006.1 - 2.2e-34 118.6 0.1 2.9e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel HTH_29 PF13551.1 EMG46007.1 - 0.0016 18.5 0.1 0.0032 17.6 0.0 1.5 1 1 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EMG46007.1 - 0.0069 16.3 0.1 0.014 15.4 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 EMG46007.1 - 0.01 15.7 0.2 0.015 15.2 0.1 1.3 1 0 0 1 1 1 0 Transposase HTH_23 PF13384.1 EMG46007.1 - 0.089 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain Nucleoporin2 PF04096.9 EMG46008.1 - 1.2e-49 167.7 1.0 2.2e-49 166.8 0.0 1.9 2 0 0 2 2 2 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EMG46008.1 - 3.9e-37 126.9 415.9 4.3e-13 49.4 29.1 10.4 2 2 8 10 10 10 6 Nucleoporin FG repeat region EMA PF02488.10 EMG46008.1 - 0.046 13.1 1.6 0.077 12.4 1.1 1.3 1 0 0 1 1 1 0 Merozoite Antigen Glyco_transf_8 PF01501.15 EMG46009.1 - 5.8e-32 110.9 1.4 8.2e-32 110.4 0.9 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 EMG46009.1 - 0.0088 15.8 0.1 0.014 15.1 0.1 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.3 EMG46009.1 - 0.065 12.5 0.2 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Rota_NS53 PF00981.12 EMG46009.1 - 0.099 11.2 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) UDG PF03167.14 EMG46010.1 - 7.9e-22 77.3 0.1 1.2e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily MSP1_C PF07462.6 EMG46010.1 - 0.0042 15.5 1.5 0.0057 15.1 1.0 1.2 1 0 0 1 1 1 1 Merozoite surface protein 1 (MSP1) C-terminus OHCU_decarbox PF09349.5 EMG46010.1 - 0.033 14.4 0.0 0.058 13.6 0.0 1.3 1 0 0 1 1 1 0 OHCU decarboxylase OST3_OST6 PF04756.8 EMG46011.1 - 1.3e-16 60.6 4.6 2.2e-16 59.8 3.2 1.4 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin_8 PF13905.1 EMG46011.1 - 0.026 14.6 3.8 0.11 12.6 0.1 3.2 3 1 1 4 4 4 0 Thioredoxin-like Glutaredoxin PF00462.19 EMG46011.1 - 0.031 14.2 0.0 0.13 12.2 0.0 2.0 2 1 0 2 2 2 0 Glutaredoxin YesK PF14150.1 EMG46011.1 - 0.69 10.0 9.0 0.051 13.6 2.1 2.2 2 1 0 2 2 2 0 YesK-like protein TPT PF03151.11 EMG46012.1 - 1.4e-09 37.8 27.2 3.6e-05 23.4 7.2 3.0 2 1 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EMG46012.1 - 6.9e-08 31.7 12.8 6.9e-08 31.7 8.9 1.5 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.15 EMG46012.1 - 7.9e-08 32.3 5.6 7.9e-08 32.3 3.8 3.4 3 1 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 EMG46012.1 - 3.9e-06 25.9 11.3 5.9e-06 25.3 7.9 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 EMG46012.1 - 0.024 14.8 1.2 0.024 14.8 0.8 3.2 3 1 1 4 4 4 0 Multidrug resistance efflux transporter UPF0546 PF10639.4 EMG46012.1 - 1.1 9.0 14.5 0.034 13.9 1.2 3.2 3 1 0 3 3 3 0 Uncharacterised protein family UPF0546 DOT1 PF08123.8 EMG46013.1 - 7.1e-70 234.4 0.1 1.8e-69 233.1 0.0 1.8 1 0 0 1 1 1 1 Histone methylation protein DOT1 SNF2_N PF00176.18 EMG46014.1 - 9.7e-80 267.5 0.3 1.6e-79 266.8 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EMG46014.1 - 1.5e-44 150.4 1.7 1.5e-44 150.4 1.2 2.8 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 EMG46014.1 - 7.8e-32 110.0 11.0 7.8e-32 110.0 7.6 3.6 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 EMG46014.1 - 1e-15 57.3 0.0 8e-15 54.4 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMG46014.1 - 4.5e-08 33.1 0.0 4.5e-08 33.1 0.0 4.8 7 1 0 7 7 7 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EMG46014.1 - 6.4e-05 22.5 0.0 0.00021 20.8 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 EMG46014.1 - 0.005 16.8 0.0 0.3 11.1 0.0 3.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain AAA_10 PF12846.2 EMG46014.1 - 6.4 6.1 9.0 0.17 11.2 0.1 2.8 2 1 0 2 2 2 0 AAA-like domain PALP PF00291.20 EMG46015.1 - 1.1e-55 189.0 0.0 1.9e-55 188.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FMO-like PF00743.14 EMG46015.1 - 3.2e-22 78.4 4.2 3.5e-13 48.5 0.5 2.5 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EMG46015.1 - 8.4e-10 39.0 0.0 2.2e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMG46015.1 - 6.6e-07 28.5 0.0 2.3e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) CLTH PF10607.4 EMG46017.1 - 3.7e-35 120.7 6.9 3.7e-35 120.7 4.8 2.3 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain FMO-like PF00743.14 EMG46017.1 - 1.7e-21 76.0 0.4 1.4e-13 49.8 0.3 2.4 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EMG46017.1 - 3.3e-11 43.6 0.0 7.8e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMG46017.1 - 1.9e-09 36.9 0.1 4.7e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) RVT_3 PF13456.1 EMG46017.1 - 0.68 9.7 3.5 11 5.8 0.2 2.7 2 0 0 2 2 2 0 Reverse transcriptase-like EAP30 PF04157.11 EMG46017.1 - 1.2 8.1 8.9 9.3 5.3 4.5 3.1 2 1 1 3 3 3 0 EAP30/Vps36 family DUF2431 PF10354.4 EMG46018.1 - 4e-61 205.7 0.1 4e-61 205.7 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) NAD_binding_8 PF13450.1 EMG46019.1 - 0.00096 19.1 0.1 0.0042 17.0 0.1 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMG46019.1 - 0.0027 17.4 0.0 0.0039 16.9 0.0 1.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EMG46019.1 - 0.005 16.9 0.1 0.0059 16.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Candida_ALS_N PF11766.3 EMG46020.1 - 3.3e-86 288.2 10.8 4e-86 287.9 7.5 1.1 1 0 0 1 1 1 1 Cell-wall agglutinin N-terminal ligand-sugar binding NAD_binding_8 PF13450.1 EMG46021.1 - 0.0025 17.7 0.2 0.011 15.7 0.1 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMG46021.1 - 0.0076 16.0 0.0 0.011 15.5 0.0 1.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EMG46021.1 - 0.025 14.6 0.1 0.029 14.4 0.1 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Endonuc-EcoRV PF09233.6 EMG46022.1 - 0.022 14.1 1.0 1.6 7.9 0.0 2.0 1 1 1 2 2 2 0 Restriction endonuclease EcoRV GDA1_CD39 PF01150.12 EMG46023.1 - 7.1e-81 271.9 0.6 3.7e-71 239.9 0.1 2.1 1 1 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 EMG46023.1 - 8.3e-05 21.9 0.0 0.00015 21.0 0.0 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Nucleoplasmin PF03066.10 EMG46024.1 - 0.3 10.5 12.8 0.57 9.6 1.8 2.4 2 0 0 2 2 2 0 Nucleoplasmin DUF1706 PF08020.6 EMG46024.1 - 0.38 10.2 9.9 0.076 12.5 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1706) Nop14 PF04147.7 EMG46024.1 - 3 5.6 14.0 2.2 6.0 0.2 2.1 2 0 0 2 2 2 0 Nop14-like family DUF4611 PF15387.1 EMG46024.1 - 7.3 6.8 12.7 11 6.3 0.9 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Fungal_trans PF04082.13 EMG46025.1 - 1.5e-71 240.3 8.9 1.5e-71 240.3 6.1 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EMG46025.1 - 1.9e-07 31.0 11.0 0.0013 18.9 2.2 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMG46025.1 - 0.00019 21.5 8.2 0.019 15.2 1.7 3.5 2 0 0 2 2 2 2 C2H2-type zinc finger Ribosomal_S8e PF01201.17 EMG46026.1 - 5.3e-40 136.6 8.5 9.4e-40 135.8 5.9 1.4 1 1 0 1 1 1 1 Ribosomal protein S8e HPD PF05044.7 EMG46026.1 - 0.026 14.2 1.2 0.032 13.9 0.1 1.6 2 0 0 2 2 2 0 Homeo-prospero domain Stathmin PF00836.14 EMG46026.1 - 0.64 9.6 11.3 5.7 6.5 4.2 2.2 2 0 0 2 2 2 0 Stathmin family DUF3959 PF13105.1 EMG46026.1 - 7.6 5.7 8.7 2.1 7.6 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) Sas10_Utp3 PF04000.10 EMG46027.1 - 4.2e-12 46.0 4.1 4.2e-12 46.0 2.9 2.4 2 0 0 2 2 2 1 Sas10/Utp3/C1D family PRELI PF04707.9 EMG46027.1 - 0.036 13.6 0.1 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 PRELI-like family EBV-NA3 PF05009.7 EMG46027.1 - 0.38 9.9 5.8 0.73 9.0 4.0 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CENP-B_dimeris PF09026.5 EMG46027.1 - 4.7 7.5 18.1 0.43 10.8 6.5 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Pro_isomerase PF00160.16 EMG46028.1 - 7.7e-44 149.6 0.7 9.1e-44 149.3 0.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DEAD PF00270.24 EMG46029.1 - 3.8e-47 159.9 0.0 4.4e-46 156.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG46029.1 - 1.6e-25 88.7 0.0 3.6e-25 87.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMG46029.1 - 0.0029 17.4 0.0 0.0066 16.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EMG46029.1 - 0.028 13.4 0.1 0.1 11.6 0.0 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit NAD_kinase PF01513.16 EMG46030.1 - 3.1e-72 242.7 0.0 4.3e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DNA_pol_B PF00136.16 EMG46032.1 - 6.2e-89 298.9 2.0 1.3e-88 297.8 1.4 1.5 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EMG46032.1 - 1e-22 80.4 16.6 3.5e-12 45.8 1.8 3.1 3 0 0 3 3 3 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EMG46032.1 - 1.6e-10 40.8 11.0 1.6e-10 40.8 7.6 2.0 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Pkinase PF00069.20 EMG46033.1 - 1.2e-55 188.5 0.0 1.6e-55 188.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG46033.1 - 1e-38 132.9 0.0 1.3e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG46033.1 - 3.3e-07 29.5 0.0 5.2e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EMG46033.1 - 0.00021 20.2 0.2 0.00081 18.3 0.0 1.8 2 0 0 2 2 2 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EMG46033.1 - 0.012 14.3 0.1 0.019 13.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 EMG46033.1 - 0.11 12.2 0.0 0.29 10.8 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Radical_SAM PF04055.16 EMG46034.1 - 5.4e-16 59.1 0.1 1.1e-15 58.2 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily MBA1 PF07961.6 EMG46035.1 - 4.6e-56 189.3 0.4 5.7e-56 188.9 0.3 1.1 1 0 0 1 1 1 1 MBA1-like protein zf-CCCH PF00642.19 EMG46037.1 - 4.4e-10 38.9 10.0 1.3e-05 24.7 1.2 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NOGCT PF08155.6 EMG46038.1 - 1.5e-27 95.0 1.9 3.5e-27 93.8 1.4 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 EMG46038.1 - 2.4e-27 94.5 0.4 5.2e-27 93.4 0.3 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EMG46038.1 - 4.9e-16 58.7 0.0 1.4e-15 57.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMG46038.1 - 3.1e-10 39.5 0.0 6.7e-10 38.4 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EMG46038.1 - 0.00087 19.7 0.0 0.0025 18.3 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EMG46038.1 - 0.046 13.5 1.4 11 5.7 0.0 3.2 2 2 1 3 3 3 0 Dynamin family Anp1 PF03452.9 EMG46040.1 - 1.1e-112 375.6 0.1 1.2e-112 375.4 0.1 1.0 1 0 0 1 1 1 1 Anp1 Glyco_transf_8 PF01501.15 EMG46040.1 - 0.0038 16.5 0.2 0.0057 16.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 DUF273 PF03314.9 EMG46040.1 - 0.016 14.5 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF273 DUF4411 PF14367.1 EMG46040.1 - 0.046 13.4 0.1 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4411) DUF2181 PF10223.4 EMG46040.1 - 0.28 10.5 2.3 1.8 7.8 0.6 2.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2181) Zn_clus PF00172.13 EMG46042.1 - 1.8e-07 30.9 12.1 3.2e-07 30.1 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sensor_TM1 PF13755.1 EMG46042.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain PAT1 PF09770.4 EMG46042.1 - 3.3 5.8 25.1 4.7 5.3 17.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GST_C_2 PF13410.1 EMG46043.1 - 1.1e-10 41.2 0.1 2.1e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMG46043.1 - 2.2e-10 40.4 0.0 2.2e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain EF1G PF00647.14 EMG46043.1 - 8.5e-08 31.8 0.0 1.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C_3 PF14497.1 EMG46043.1 - 0.00013 22.3 0.1 0.00029 21.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMG46043.1 - 0.00022 21.3 0.0 0.0012 19.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMG46043.1 - 0.043 14.0 0.4 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Fungal_trans PF04082.13 EMG46044.1 - 2.8e-12 46.0 0.1 9.7e-12 44.3 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG46044.1 - 4.5e-08 32.8 12.0 4.5e-08 32.8 8.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EMG46045.1 - 1.8e-104 349.8 25.9 2e-104 349.6 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG46045.1 - 2.7e-18 65.8 34.6 2.9e-14 52.5 8.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily PQ-loop PF04193.9 EMG46046.1 - 6.3e-40 134.5 18.4 1.5e-22 78.8 0.9 2.8 3 0 0 3 3 3 2 PQ loop repeat PgaD PF13994.1 EMG46046.1 - 0.15 11.5 1.4 0.93 8.9 0.0 2.8 2 2 0 3 3 3 0 PgaD-like protein DUF3671 PF12420.3 EMG46046.1 - 1.5 8.8 4.2 6.8 6.7 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function Zn_clus PF00172.13 EMG46047.1 - 3.2e-09 36.5 11.4 7e-09 35.4 7.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMG46047.1 - 0.00081 18.3 0.2 0.0019 17.0 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.23 EMG46048.1 - 7e-58 195.9 0.0 2.1e-57 194.3 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme RRM_6 PF14259.1 EMG46049.1 - 1.9e-06 27.7 0.1 0.043 13.8 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMG46049.1 - 2.6e-05 23.7 0.1 0.76 9.4 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG46049.1 - 0.0085 15.9 0.0 0.047 13.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Flavoprotein PF02441.14 EMG46050.1 - 7.8e-40 135.5 0.1 1.4e-39 134.7 0.1 1.4 1 0 0 1 1 1 1 Flavoprotein MAP65_ASE1 PF03999.7 EMG46051.1 - 4.2e-46 157.7 47.5 7.4e-45 153.6 32.9 2.0 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DUF442 PF04273.8 EMG46051.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative phosphatase (DUF442) DUF4393 PF14337.1 EMG46052.1 - 0.034 13.5 5.3 0.024 14.1 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4393) Zn_clus PF00172.13 EMG46053.1 - 2.3e-08 33.7 11.6 6.6e-08 32.3 8.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMG46053.1 - 4.1e-08 32.4 9.0 1.9e-06 26.9 0.8 3.5 3 1 0 3 3 3 2 Fungal specific transcription factor domain SKN1 PF03935.10 EMG46054.1 - 2.1e-238 791.5 5.1 2.4e-238 791.3 3.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) tRNA_int_end_N2 PF12928.2 EMG46055.1 - 2.8e-15 55.5 0.0 5.5e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term Cornichon PF03311.9 EMG46055.1 - 0.088 12.9 0.1 0.32 11.1 0.0 1.9 2 0 0 2 2 2 0 Cornichon protein SKN1 PF03935.10 EMG46057.1 - 7.7e-255 845.7 1.6 1.1e-254 845.1 1.1 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) CM_2 PF01817.16 EMG46059.1 - 0.053 13.6 0.0 0.059 13.4 0.0 1.0 1 0 0 1 1 1 0 Chorismate mutase type II F-box-like PF12937.2 EMG46060.1 - 2e-05 24.1 0.1 6.2e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMG46060.1 - 9.3e-05 21.9 0.6 0.00047 19.7 0.3 2.4 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.1 EMG46060.1 - 2 8.2 31.5 0.17 11.6 1.2 6.4 5 1 2 7 7 7 0 Leucine rich repeat LRR_4 PF12799.2 EMG46060.1 - 6.1 6.5 32.2 0.22 11.1 1.8 6.7 5 3 2 7 7 7 0 Leucine Rich repeats (2 copies) Sec2p PF06428.6 EMG46061.1 - 2.3e-29 101.1 11.9 2.3e-29 101.1 8.3 2.9 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p ATG16 PF08614.6 EMG46061.1 - 0.00055 19.8 11.0 0.00055 19.8 7.6 3.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) FA_desaturase PF00487.19 EMG46063.1 - 1.7e-20 73.5 18.5 2.7e-20 72.9 12.8 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EMG46063.1 - 8.2e-08 32.3 0.0 1.6e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) GTP_EFTU PF00009.22 EMG46064.1 - 2.3e-59 200.0 0.1 4.1e-59 199.1 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EMG46064.1 - 2e-33 114.4 0.0 5e-33 113.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 EMG46064.1 - 2.8e-30 103.9 0.0 7e-30 102.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EMG46064.1 - 8.4e-21 73.6 0.0 1.9e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EMG46064.1 - 1.2e-12 47.7 0.1 4.3e-12 45.9 0.1 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMG46064.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 EMG46064.1 - 0.099 13.1 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Ribosomal_L14e PF01929.12 EMG46065.1 - 1.9e-32 111.4 2.2 2.6e-32 111.0 1.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 tRNA-synt_1e PF01406.14 EMG46066.1 - 7.9e-136 452.0 4.8 7.9e-136 452.0 3.3 2.0 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EMG46066.1 - 2.4e-08 33.0 5.6 1.6e-05 23.7 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EMG46066.1 - 0.00011 20.3 0.0 0.00011 20.3 0.0 2.2 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) RecO_C PF02565.10 EMG46066.1 - 0.097 12.5 0.3 3 7.7 0.0 2.9 3 0 0 3 3 3 0 Recombination protein O C terminal SPC22 PF04573.7 EMG46067.1 - 3.7e-45 153.2 1.2 4.6e-45 152.9 0.8 1.0 1 0 0 1 1 1 1 Signal peptidase subunit PPR_2 PF13041.1 EMG46068.1 - 0.00059 19.7 4.4 1.7 8.6 0.1 5.0 5 0 0 5 5 5 3 PPR repeat family PPR PF01535.15 EMG46068.1 - 0.044 13.7 2.4 10 6.3 0.0 4.5 4 0 0 4 4 4 0 PPR repeat Chitin_synth_2 PF03142.10 EMG46070.1 - 2.3e-291 966.7 0.3 3.4e-291 966.2 0.2 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EMG46070.1 - 2.9e-19 69.5 1.5 1e-18 67.7 1.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMG46070.1 - 2.2e-16 60.3 0.0 1.2e-14 54.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EMG46070.1 - 3.3e-05 23.6 0.0 0.0065 16.2 0.0 3.0 2 1 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EMG46070.1 - 3.3e-05 23.2 0.1 0.00013 21.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EMG46070.1 - 0.00018 21.2 0.0 0.0037 16.9 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 DLIC PF05783.6 EMG46071.1 - 5.2 5.6 6.6 7.6 5.0 4.6 1.4 1 1 0 1 1 1 0 Dynein light intermediate chain (DLIC) RNase_T PF00929.19 EMG46072.1 - 7.3e-20 71.8 0.0 1.2e-19 71.1 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EMG46072.1 - 0.002 17.6 0.0 0.005 16.3 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease HLH PF00010.21 EMG46073.1 - 3.5e-19 68.2 0.7 7.1e-19 67.2 0.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Nnf1 PF03980.9 EMG46073.1 - 0.45 10.5 10.0 0.39 10.7 0.6 2.3 2 0 0 2 2 2 0 Nnf1 NARP1 PF12569.3 EMG46073.1 - 0.98 8.0 12.9 1.3 7.6 8.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Tmemb_9 PF05434.6 EMG46075.1 - 0.011 15.4 0.3 0.015 15.0 0.2 1.3 1 0 0 1 1 1 0 TMEM9 Dexa_ind PF15198.1 EMG46075.1 - 2.2 8.2 11.9 1.4 8.8 3.9 2.1 1 1 1 2 2 2 0 Dexamethasone-induced DUF4149 PF13664.1 EMG46076.1 - 3e-22 78.5 2.6 2.5e-21 75.6 0.7 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4149) MutS_V PF00488.16 EMG46078.1 - 1.5e-76 256.8 0.0 2.7e-76 256.0 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EMG46078.1 - 7.1e-43 146.7 0.2 1.2e-42 146.0 0.2 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EMG46078.1 - 1.1e-31 109.1 0.0 2.5e-31 108.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EMG46078.1 - 2.3e-12 47.1 0.7 7.2e-12 45.5 0.0 2.2 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EMG46078.1 - 7.4e-11 42.0 3.6 1.1e-10 41.4 0.8 2.8 3 0 0 3 3 3 1 MutS family domain IV AAA_29 PF13555.1 EMG46078.1 - 0.014 14.9 0.1 0.044 13.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RP-C PF03428.8 EMG46078.1 - 0.049 13.0 0.1 0.28 10.6 0.0 2.2 2 0 0 2 2 2 0 Replication protein C N-terminal domain NTP_transferase PF00483.18 EMG46079.1 - 1.4e-17 63.8 0.0 2.1e-11 43.6 0.0 2.8 3 0 0 3 3 3 2 Nucleotidyl transferase Hexapep PF00132.19 EMG46079.1 - 3.7e-07 29.3 16.7 0.00068 19.0 1.4 4.8 3 1 2 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.7 EMG46079.1 - 0.0051 15.4 4.2 0.1 11.1 0.7 2.8 2 1 1 3 3 3 1 L-fucokinase NTP_transf_3 PF12804.2 EMG46079.1 - 0.0084 16.1 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EMG46079.1 - 0.26 10.8 11.0 1.1e+02 2.5 7.6 3.2 1 1 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase AA_permease PF00324.16 EMG46080.1 - 6.6e-104 347.8 43.3 8.1e-104 347.6 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG46080.1 - 1.5e-34 119.2 48.2 1.8e-34 119.0 33.4 1.0 1 0 0 1 1 1 1 Amino acid permease ATP_synt_H PF05493.8 EMG46080.1 - 0.022 14.8 0.5 0.022 14.8 0.3 3.6 3 0 0 3 3 3 0 ATP synthase subunit H Sec7_N PF12783.2 EMG46081.1 - 4.3e-42 143.4 7.1 4.3e-42 143.4 4.9 2.4 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF4112 PF13430.1 EMG46082.1 - 1.9e-28 98.4 0.3 2.6e-28 98.0 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF4389 PF14333.1 EMG46083.1 - 0.23 11.1 0.6 0.59 9.8 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) DDE_1 PF03184.14 EMG46085.1 - 8.7e-41 139.4 0.1 8.4e-28 96.9 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease DDE_3 PF13358.1 EMG46085.1 - 5.6e-09 35.8 0.0 1.4e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EMG46085.1 - 9.2e-06 25.3 0.4 2.1e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain rve PF00665.21 EMG46085.1 - 0.01 15.9 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain HTH_psq PF05225.11 EMG46085.1 - 0.016 14.7 0.0 0.034 13.6 0.0 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain DUF4639 PF15479.1 EMG46086.1 - 0.62 8.6 5.6 0.83 8.2 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) Recep_L_domain PF01030.19 EMG46087.1 - 8.2e-10 38.6 13.6 0.084 12.8 0.3 5.1 1 1 3 5 5 5 5 Receptor L domain LRR_7 PF13504.1 EMG46087.1 - 3.1 8.4 7.7 49 4.7 0.2 5.2 4 1 0 4 4 4 0 Leucine rich repeat CTP_transf_2 PF01467.21 EMG46088.1 - 0.00011 22.2 0.1 0.00037 20.5 0.1 1.8 1 1 0 1 1 1 1 Cytidylyltransferase SWIB PF02201.13 EMG46088.1 - 0.032 13.9 0.0 0.92 9.2 0.0 2.5 2 0 0 2 2 2 0 SWIB/MDM2 domain FKBP_C PF00254.23 EMG46089.1 - 6e-30 103.1 0.0 9.3e-30 102.5 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NA37 PF04245.8 EMG46089.1 - 0.087 12.1 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein AFT PF08731.6 EMG46090.1 - 5.8e-05 23.2 0.0 5.8e-05 23.2 0.0 4.5 4 1 0 4 4 4 1 Transcription factor AFT DBD_Tnp_Mut PF03108.10 EMG46090.1 - 0.0024 17.4 0.0 0.017 14.7 0.0 2.2 2 0 0 2 2 2 1 MuDR family transposase Neur_chan_memb PF02932.11 EMG46090.1 - 0.48 10.2 15.6 0.7 9.7 4.1 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.4 EMG46090.1 - 5.4 5.1 49.5 3.1 5.9 19.8 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 CRAL_TRIO_2 PF13716.1 EMG46091.1 - 3.1e-37 127.7 4.0 3.1e-37 127.7 2.8 2.3 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 EMG46091.1 - 1.2e-09 37.9 0.3 3.6e-09 36.4 0.2 1.8 1 0 0 1 1 1 1 RhoGAP domain Colicin_Pyocin PF01320.13 EMG46091.1 - 1.9 8.4 6.3 3.1 7.7 0.1 3.1 3 0 0 3 3 3 0 Colicin immunity protein / pyocin immunity protein PC_rep PF01851.17 EMG46092.1 - 4.8e-27 92.6 11.3 9e-05 22.4 0.2 10.0 10 0 0 10 10 10 5 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EMG46092.1 - 7.1e-05 23.0 0.7 0.65 10.3 0.0 3.5 3 0 0 3 3 3 2 HEAT repeats Ycf1 PF05758.7 EMG46092.1 - 1.4 6.4 6.7 0.12 10.0 0.1 2.0 2 0 0 2 2 2 0 Ycf1 ATP-synt_C PF00137.16 EMG46093.1 - 1.2e-28 98.8 24.5 3.7e-16 58.7 5.7 2.3 2 0 0 2 2 2 2 ATP synthase subunit C Sensor_TM1 PF13755.1 EMG46093.1 - 0.031 13.7 0.4 0.73 9.3 0.0 2.4 2 0 0 2 2 2 0 Sensor N-terminal transmembrane domain zf-H2C2_2 PF13465.1 EMG46094.1 - 9.7e-05 22.4 11.1 0.0055 16.9 1.1 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMG46094.1 - 0.00032 20.8 15.2 0.00087 19.4 1.6 3.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMG46094.1 - 0.0034 17.6 1.3 0.0034 17.6 0.9 3.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-Di19 PF05605.7 EMG46094.1 - 0.021 14.9 8.0 0.056 13.5 2.8 2.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding GN3L_Grn1 PF08701.6 EMG46094.1 - 0.49 10.3 10.4 1 9.3 7.2 1.5 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase zf-BED PF02892.10 EMG46094.1 - 3.7 7.4 6.9 0.83 9.4 0.9 2.6 3 0 0 3 3 3 0 BED zinc finger PAT1 PF09770.4 EMG46094.1 - 5.1 5.2 20.7 7.5 4.6 14.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spermine_synth PF01564.12 EMG46095.1 - 3.7e-80 268.4 0.6 5.5e-80 267.8 0.4 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 EMG46095.1 - 0.0021 17.6 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 EMG46095.1 - 0.028 13.4 0.2 0.055 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF43 Stn1_C PF12659.2 EMG46095.1 - 0.056 13.2 0.3 0.18 11.6 0.1 1.9 2 0 0 2 2 2 0 Telomere capping C-terminal wHTH NAD_binding_7 PF13241.1 EMG46095.1 - 0.1 12.8 0.0 0.33 11.2 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Bud13 PF09736.4 EMG46097.1 - 4.1e-22 79.0 23.0 5.1e-22 78.7 10.5 3.0 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex IncA PF04156.9 EMG46097.1 - 0.86 9.1 5.3 1.5 8.3 3.7 1.3 1 0 0 1 1 1 0 IncA protein SPATIAL PF15256.1 EMG46097.1 - 4.3 7.3 8.1 11 6.0 5.6 1.7 1 1 0 1 1 1 0 SPATIAL TPR_11 PF13414.1 EMG46098.1 - 2.1e-11 43.2 5.9 0.00021 20.8 0.0 3.4 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.1 EMG46098.1 - 5.1e-08 33.3 0.0 0.00025 21.6 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMG46098.1 - 1.6e-07 30.7 0.7 0.01 15.7 0.0 4.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMG46098.1 - 1e-06 28.8 0.1 0.25 12.1 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMG46098.1 - 1.2e-06 28.3 1.3 0.11 12.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EMG46098.1 - 1.7e-06 28.0 0.1 0.13 12.4 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EMG46098.1 - 8.2e-06 26.0 4.2 0.75 10.1 0.0 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EMG46098.1 - 4e-05 23.0 1.4 0.0054 16.2 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMG46098.1 - 0.00012 21.6 1.0 0.48 10.3 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMG46098.1 - 0.018 15.2 1.6 2.1 8.7 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMG46098.1 - 0.022 14.5 1.0 22 5.1 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Ph1570 PF09638.5 EMG46099.1 - 0.016 15.0 0.8 0.048 13.4 0.0 2.2 2 1 0 2 2 2 0 Ph1570 protein DEK_C PF08766.6 EMG46099.1 - 0.027 14.2 0.7 7.1 6.4 0.2 2.9 3 0 0 3 3 3 0 DEK C terminal domain XRN_N PF03159.13 EMG46100.1 - 3.9e-99 330.8 0.2 3.9e-99 330.8 0.1 2.3 3 0 0 3 3 3 1 XRN 5'-3' exonuclease N-terminus Glutaredoxin PF00462.19 EMG46101.1 - 0.047 13.6 2.0 0.074 13.0 0.1 2.2 3 0 0 3 3 3 0 Glutaredoxin CHCH PF06747.8 EMG46102.1 - 0.00082 19.2 4.8 0.0012 18.7 3.3 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 EMG46102.1 - 0.013 15.2 2.1 0.019 14.7 1.5 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EMG46102.1 - 0.16 12.0 4.1 0.31 11.1 1.3 1.9 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.8 EMG46102.1 - 0.23 11.4 4.1 0.49 10.4 0.5 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Mito_carr PF00153.22 EMG46103.1 - 2.4e-74 245.1 0.7 1.2e-25 88.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein YebF PF13995.1 EMG46103.1 - 0.0045 16.9 0.2 0.038 13.9 0.0 2.6 3 0 0 3 3 3 1 YebF-like protein DUF3686 PF12458.3 EMG46103.1 - 0.0089 14.3 0.4 0.017 13.3 0.1 1.5 2 0 0 2 2 2 1 ATPase involved in DNA repair EF-hand_7 PF13499.1 EMG46103.1 - 0.011 15.8 6.1 19 5.5 0.0 5.5 4 2 2 6 6 6 0 EF-hand domain pair EF-hand_1 PF00036.27 EMG46103.1 - 0.029 13.6 4.0 24 4.5 0.0 5.1 6 0 0 6 6 6 0 EF hand YtxH PF12732.2 EMG46103.1 - 0.12 12.7 0.2 0.52 10.6 0.1 2.2 1 0 0 1 1 1 0 YtxH-like protein Sep15_SelM PF08806.6 EMG46104.1 - 0.074 12.8 0.0 0.47 10.2 0.0 2.3 2 1 0 2 2 2 0 Sep15/SelM redox domain zf-H2C2_2 PF13465.1 EMG46105.1 - 8.5e-12 44.7 14.0 1.7e-08 34.3 1.1 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMG46105.1 - 7.7e-11 41.6 20.2 7.5e-05 22.8 0.4 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMG46105.1 - 6.6e-08 32.3 17.7 0.0039 17.4 0.2 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMG46105.1 - 0.0027 17.8 8.0 0.71 10.1 0.2 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMG46105.1 - 0.0029 17.4 7.6 1.2 9.1 0.0 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EMG46105.1 - 0.0076 15.8 1.1 0.0076 15.8 0.8 1.9 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-met PF12874.2 EMG46105.1 - 0.067 13.4 8.4 0.68 10.2 0.3 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type C1_4 PF07975.7 EMG46105.1 - 0.66 10.0 6.5 27 4.8 0.2 2.6 1 1 1 2 2 2 0 TFIIH C1-like domain Endonuclease_7 PF02945.10 EMG46105.1 - 0.9 9.2 5.8 0.33 10.6 1.7 2.0 1 1 1 2 2 2 0 Recombination endonuclease VII zf-CHY PF05495.7 EMG46105.1 - 1.4 9.1 9.8 3.6 7.7 5.6 2.3 1 1 1 2 2 2 0 CHY zinc finger Glutaredoxin PF00462.19 EMG46106.1 - 0.036 14.0 0.2 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 Glutaredoxin Pkinase PF00069.20 EMG46108.1 - 3.7e-55 186.8 0.0 7.6e-55 185.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG46108.1 - 3.6e-19 68.8 0.0 1.3e-18 67.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Myc_N PF01056.13 EMG46108.1 - 0.053 12.6 4.6 0.09 11.9 3.2 1.3 1 0 0 1 1 1 0 Myc amino-terminal region HSP70 PF00012.15 EMG46109.1 - 2e-55 187.8 0.1 2.3e-55 187.6 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein FGGY_C PF02782.11 EMG46109.1 - 5.9e-05 22.7 0.0 6.7e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MreB_Mbl PF06723.8 EMG46109.1 - 0.0074 14.9 0.0 0.0087 14.6 0.0 1.0 1 0 0 1 1 1 1 MreB/Mbl protein DUF1464 PF07318.7 EMG46109.1 - 0.032 13.0 0.0 0.034 12.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) BcrAD_BadFG PF01869.15 EMG46109.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Nucleoporin_FG PF13634.1 EMG46110.1 - 4.1e-38 130.1 114.3 3.5e-21 75.5 32.2 3.4 1 1 2 3 3 3 3 Nucleoporin FG repeat region MBOAT PF03062.14 EMG46111.1 - 7e-58 196.2 23.1 1.3e-57 195.3 16.0 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Abhydro_lipase PF04083.11 EMG46113.1 - 1.5e-16 59.5 0.8 2.9e-16 58.5 0.5 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EMG46113.1 - 1.1e-07 31.6 0.0 2.6e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 EMG46113.1 - 3.3e-05 23.4 0.0 0.079 12.3 0.0 2.7 3 1 0 3 3 3 2 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EMG46113.1 - 0.00034 20.5 0.0 0.00055 19.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMG46113.1 - 0.00056 19.6 0.0 0.012 15.3 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EMG46113.1 - 0.0044 16.4 0.0 0.029 13.7 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Na_Ca_ex PF01699.19 EMG46114.1 - 3.1e-36 124.0 32.2 3e-22 78.7 6.9 2.7 2 1 1 3 3 3 2 Sodium/calcium exchanger protein HSP70 PF00012.15 EMG46115.1 - 4.7e-12 44.6 5.8 5.3e-12 44.4 4.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Gly-zipper_OmpA PF13436.1 EMG46115.1 - 0.14 11.8 5.3 0.22 11.2 3.6 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain PUF PF00806.14 EMG46116.1 - 4.3e-49 161.3 33.6 2.1e-07 30.0 0.2 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Atg14 PF10186.4 EMG46117.1 - 0.029 13.3 6.5 0.063 12.2 4.5 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF641 PF04859.7 EMG46117.1 - 0.27 10.9 6.3 0.17 11.6 2.7 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) CDC37_N PF03234.9 EMG46117.1 - 6.4 7.0 16.2 0.29 11.4 4.3 2.8 3 0 0 3 3 3 0 Cdc37 N terminal kinase binding AMPKBI PF04739.10 EMG46118.1 - 1.6e-42 143.4 1.8 1.6e-42 143.4 1.2 2.8 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain AAA PF00004.24 EMG46120.1 - 1.3e-53 180.7 0.0 9.6e-38 129.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMG46120.1 - 9.6e-11 41.9 2.5 0.00048 20.2 0.2 4.2 2 2 0 2 2 2 2 AAA domain CDC48_N PF02359.13 EMG46120.1 - 1.2e-10 41.1 0.0 4.1e-10 39.4 0.0 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_17 PF13207.1 EMG46120.1 - 4.8e-10 40.2 0.1 0.0013 19.5 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 EMG46120.1 - 8.5e-10 39.0 0.1 0.0001 22.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.9 EMG46120.1 - 1.7e-09 37.4 0.2 7.2e-05 22.5 0.1 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EMG46120.1 - 2.1e-09 36.6 0.1 0.00033 19.4 0.0 2.5 3 0 0 3 3 2 2 TIP49 C-terminus AAA_16 PF13191.1 EMG46120.1 - 4e-08 33.4 0.0 0.0057 16.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.7 EMG46120.1 - 4.3e-08 32.4 0.1 0.00036 19.6 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EMG46120.1 - 1.1e-07 31.9 0.0 6.9e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EMG46120.1 - 2.1e-07 30.3 0.2 0.0019 17.3 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EMG46120.1 - 5.7e-07 29.1 0.0 0.016 14.6 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 EMG46120.1 - 2.4e-06 27.4 0.0 0.029 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EMG46120.1 - 4.3e-06 26.8 0.0 0.065 13.4 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_24 PF13479.1 EMG46120.1 - 6.8e-06 25.8 0.1 0.034 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 EMG46120.1 - 6.9e-06 25.6 0.7 7.3e-05 22.3 0.1 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_19 PF13245.1 EMG46120.1 - 1.5e-05 24.6 0.1 0.032 13.9 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain AAA_33 PF13671.1 EMG46120.1 - 3.6e-05 23.6 0.0 0.13 12.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_3 PF07726.6 EMG46120.1 - 6.5e-05 22.5 0.0 0.078 12.5 0.0 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EMG46120.1 - 0.0002 21.6 0.0 0.013 15.8 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_28 PF13521.1 EMG46120.1 - 0.00021 21.3 0.0 0.26 11.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EMG46120.1 - 0.00024 20.5 5.8 0.13 11.6 0.3 3.9 2 2 2 4 4 4 1 AAA domain Zeta_toxin PF06414.7 EMG46120.1 - 0.00048 19.2 0.0 0.59 9.1 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin ATP-synt_ab PF00006.20 EMG46120.1 - 0.00056 19.4 0.0 0.98 8.8 0.0 2.4 1 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.21 EMG46120.1 - 0.0019 17.7 0.0 2.4 7.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF2075 PF09848.4 EMG46120.1 - 0.0021 17.1 0.1 0.05 12.5 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) KTI12 PF08433.5 EMG46120.1 - 0.0028 16.9 0.0 0.2 10.8 0.0 2.4 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Sigma54_activ_2 PF14532.1 EMG46120.1 - 0.0034 17.4 0.0 1.4 8.9 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 EMG46120.1 - 0.0038 16.9 3.5 0.59 9.7 0.1 3.6 2 2 1 3 3 3 1 Archaeal ATPase PhoH PF02562.11 EMG46120.1 - 0.0041 16.3 0.0 2.5 7.2 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein NACHT PF05729.7 EMG46120.1 - 0.0061 16.2 1.1 3.6 7.2 0.0 3.2 4 0 0 4 4 2 0 NACHT domain Parvo_NS1 PF01057.12 EMG46120.1 - 0.0077 15.1 0.0 1.8 7.3 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EMG46120.1 - 0.008 15.0 0.0 1.1 8.0 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_11 PF13086.1 EMG46120.1 - 0.008 15.7 0.0 1.9 8.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 EMG46120.1 - 0.0088 14.7 0.0 0.16 10.5 0.0 2.4 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein KaiC PF06745.8 EMG46120.1 - 0.013 14.6 0.1 4.9 6.2 0.0 2.9 3 0 0 3 3 3 0 KaiC SRP54 PF00448.17 EMG46120.1 - 0.015 14.7 0.0 2.6 7.4 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain KAP_NTPase PF07693.9 EMG46120.1 - 0.017 14.1 0.0 2.3 7.1 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain UPF0079 PF02367.12 EMG46120.1 - 0.032 13.8 0.1 1.3 8.6 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 IPT PF01745.11 EMG46120.1 - 0.046 12.8 0.0 1.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Isopentenyl transferase NTPase_1 PF03266.10 EMG46120.1 - 0.048 13.3 1.3 5.4 6.6 0.0 3.1 2 1 1 3 3 3 0 NTPase PPV_E1_C PF00519.12 EMG46120.1 - 0.095 11.2 0.1 0.5 8.9 0.0 1.9 2 0 0 2 2 2 0 Papillomavirus helicase SKI PF01202.17 EMG46120.1 - 0.11 12.3 0.1 13 5.5 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase Actin PF00022.14 EMG46121.1 - 3.3e-152 506.4 0.0 3.8e-152 506.2 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EMG46121.1 - 0.032 14.6 0.0 0.16 12.4 0.0 2.1 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Phosphodiest PF01663.17 EMG46121.1 - 0.072 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase OPT PF03169.10 EMG46122.1 - 7.3e-172 573.0 37.2 8.5e-172 572.8 25.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Fungal_trans PF04082.13 EMG46123.1 - 1.8e-10 40.1 0.0 1.8e-10 40.1 0.0 3.3 3 2 1 4 4 4 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG46123.1 - 8.3e-08 32.0 14.1 2.1e-07 30.7 9.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NTPase_1 PF03266.10 EMG46123.1 - 0.069 12.8 0.3 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 NTPase PAT1 PF09770.4 EMG46123.1 - 8.6 4.4 102.0 0.79 7.8 35.7 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Synaptobrevin PF00957.16 EMG46124.1 - 1.8e-32 110.7 1.4 2.1e-32 110.5 0.9 1.0 1 0 0 1 1 1 1 Synaptobrevin MtrG PF04210.8 EMG46124.1 - 7.4 6.3 8.2 40 3.9 5.6 2.1 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G GCV_H PF01597.14 EMG46125.1 - 4.7e-40 136.0 0.3 5.8e-40 135.7 0.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 EMG46125.1 - 0.00037 20.0 0.2 0.0059 16.2 0.1 2.1 1 1 0 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.1 EMG46125.1 - 0.0072 16.0 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain FAD_binding_2 PF00890.19 EMG46126.1 - 1.6e-84 284.2 0.0 1.9e-84 283.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EMG46126.1 - 4.1e-23 80.9 0.5 1.1e-20 73.2 0.0 3.8 4 0 0 4 4 4 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EMG46126.1 - 7.9e-11 41.4 0.2 1.1e-09 37.7 0.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EMG46126.1 - 2.5e-07 30.1 0.0 5.3e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMG46126.1 - 5.6e-07 29.6 2.0 8.2e-05 22.5 1.4 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMG46126.1 - 7.1e-06 25.9 1.9 2.6e-05 24.1 0.3 2.6 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EMG46126.1 - 0.00081 17.9 2.2 0.016 13.7 0.1 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 EMG46126.1 - 0.0073 15.3 0.3 0.011 14.7 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EMG46126.1 - 0.014 15.4 0.1 0.038 14.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMG46126.1 - 0.019 13.8 0.9 0.019 13.8 0.6 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A Thi4 PF01946.12 EMG46126.1 - 0.12 11.4 4.3 3.1 6.8 0.1 3.4 4 0 0 4 4 4 0 Thi4 family SNF2_N PF00176.18 EMG46127.1 - 1.4e-68 230.9 0.0 2.1e-68 230.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EMG46127.1 - 1.5e-56 191.3 4.6 2.5e-56 190.5 3.2 1.4 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 EMG46127.1 - 3.6e-13 49.1 0.0 8.3e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EMG46127.1 - 3.6e-08 32.5 0.1 1.1e-07 30.9 0.1 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 EMG46127.1 - 1.9e-05 24.1 0.0 7.3e-05 22.3 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 EMG46127.1 - 0.0021 17.9 0.0 0.0081 16.0 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EMG46127.1 - 0.053 13.6 0.0 0.24 11.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain Ran-binding PF05508.6 EMG46128.1 - 7.3e-106 353.4 2.3 7.3e-106 353.4 1.6 1.5 2 0 0 2 2 2 1 RanGTP-binding protein Nucleoplasmin PF03066.10 EMG46128.1 - 0.0011 18.5 2.2 0.0023 17.4 1.5 1.5 1 0 0 1 1 1 1 Nucleoplasmin PBP1_TM PF14812.1 EMG46128.1 - 0.0056 16.9 4.3 0.0056 16.9 3.0 2.2 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Helicase_C PF00271.26 EMG46128.1 - 0.019 14.8 0.2 15 5.5 0.0 3.4 3 0 0 3 3 3 0 Helicase conserved C-terminal domain Copper-fist PF00649.13 EMG46129.1 - 6.6e-20 70.0 1.0 6.6e-20 70.0 0.7 2.4 1 1 1 2 2 2 1 Copper fist DNA binding domain VESA1_N PF12785.2 EMG46129.1 - 0.5 9.2 18.8 0.92 8.4 13.1 1.4 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 FMN_dh PF01070.13 EMG46130.1 - 3.1e-114 381.5 0.0 4.2e-114 381.1 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EMG46130.1 - 6.3e-27 93.1 0.2 1.5e-26 91.9 0.1 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EMG46130.1 - 2.7e-06 26.5 0.0 4.7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EMG46130.1 - 0.0013 17.6 0.1 0.0029 16.5 0.0 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain OPT PF03169.10 EMG46131.1 - 1.4e-173 578.7 38.7 1.6e-173 578.5 26.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Atrophin-1 PF03154.10 EMG46132.1 - 0.0016 16.7 4.1 0.0017 16.6 2.9 1.0 1 0 0 1 1 1 1 Atrophin-1 family Ycf1 PF05758.7 EMG46132.1 - 0.0094 13.7 4.5 0.009 13.7 3.2 1.0 1 0 0 1 1 1 1 Ycf1 SID-1_RNA_chan PF13965.1 EMG46132.1 - 0.017 13.2 1.9 0.02 13.1 1.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TRAP_alpha PF03896.11 EMG46132.1 - 0.022 13.7 5.5 0.025 13.5 3.8 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF3260 PF11658.3 EMG46132.1 - 0.04 12.0 0.7 0.044 11.9 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) TraH_2 PF06871.6 EMG46132.1 - 0.042 13.2 3.8 0.052 12.9 2.6 1.1 1 0 0 1 1 1 0 TraH_2 Band_3_cyto PF07565.8 EMG46132.1 - 0.045 13.2 2.0 0.052 13.0 1.4 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain RabGAP-TBC PF00566.13 EMG46132.1 - 0.053 12.9 2.4 0.056 12.9 1.6 1.2 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Serinc PF03348.10 EMG46132.1 - 0.059 12.0 0.9 0.062 11.9 0.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF788 PF05620.6 EMG46132.1 - 0.07 12.9 0.5 0.089 12.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Zip PF02535.17 EMG46132.1 - 0.078 11.9 1.3 0.078 11.9 0.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1510 PF07423.6 EMG46132.1 - 0.079 12.3 15.6 0.092 12.0 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FAM176 PF14851.1 EMG46132.1 - 0.094 12.3 7.1 0.12 12.0 4.9 1.1 1 0 0 1 1 1 0 FAM176 family Mem_trans PF03547.13 EMG46132.1 - 0.098 10.9 4.2 0.11 10.7 2.9 1.0 1 0 0 1 1 1 0 Membrane transport protein Bap31 PF05529.7 EMG46132.1 - 0.1 12.0 4.8 0.11 11.9 3.3 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Kei1 PF08552.6 EMG46132.1 - 0.1 12.2 1.1 0.12 12.0 0.8 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 PEX11 PF05648.9 EMG46132.1 - 0.14 11.4 0.9 0.16 11.2 0.6 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Herpes_UL46 PF03387.9 EMG46132.1 - 0.16 10.1 1.0 0.16 10.1 0.7 1.0 1 0 0 1 1 1 0 Herpesvirus UL46 protein FAM60A PF15396.1 EMG46132.1 - 0.21 11.2 4.2 0.25 11.0 2.9 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Pox_Ag35 PF03286.9 EMG46132.1 - 0.23 10.9 14.6 0.27 10.7 10.1 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FHIPEP PF00771.15 EMG46132.1 - 0.23 9.7 1.2 0.22 9.8 0.8 1.0 1 0 0 1 1 1 0 FHIPEP family Folate_carrier PF01770.13 EMG46132.1 - 0.28 9.6 1.5 0.3 9.5 1.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier Trypan_PARP PF05887.6 EMG46132.1 - 0.32 10.8 11.7 0.37 10.5 8.1 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) OATP PF03137.15 EMG46132.1 - 0.32 8.9 1.6 0.37 8.7 1.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2722 PF10846.3 EMG46132.1 - 0.41 9.6 11.0 0.49 9.3 7.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Sec62 PF03839.11 EMG46132.1 - 0.41 10.0 8.0 0.49 9.7 5.5 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF3513 PF12026.3 EMG46132.1 - 0.73 9.3 7.4 0.89 9.0 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Peptidase_S49_N PF08496.5 EMG46132.1 - 0.76 9.5 8.0 0.94 9.2 5.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3537 PF12056.3 EMG46132.1 - 0.78 8.3 4.1 0.89 8.1 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) RR_TM4-6 PF06459.7 EMG46132.1 - 0.93 9.3 14.9 1.1 9.0 10.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 EMG46132.1 - 0.98 7.3 9.3 1 7.2 6.4 1.0 1 0 0 1 1 1 0 CDC45-like protein AIF_C PF14721.1 EMG46132.1 - 1 9.6 9.3 1.3 9.2 6.5 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Tim54 PF11711.3 EMG46132.1 - 1.1 7.8 10.6 1.2 7.6 7.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DDHD PF02862.12 EMG46132.1 - 1.1 9.0 8.5 1.2 8.8 5.9 1.1 1 0 0 1 1 1 0 DDHD domain Daxx PF03344.10 EMG46132.1 - 1.2 7.5 18.9 1.4 7.3 13.1 1.0 1 0 0 1 1 1 0 Daxx Family Conotoxin PF02950.12 EMG46132.1 - 1.2 10.0 4.6 2.4 9.0 3.2 1.7 1 1 0 1 1 1 0 Conotoxin Vfa1 PF08432.5 EMG46132.1 - 1.2 9.1 16.6 1.5 8.8 11.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ribosomal_L6e PF01159.14 EMG46132.1 - 1.4 9.2 8.8 1.8 8.8 6.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L6e DDRGK PF09756.4 EMG46132.1 - 1.4 8.2 19.2 1.7 8.0 13.3 1.0 1 0 0 1 1 1 0 DDRGK domain RRN3 PF05327.6 EMG46132.1 - 1.5 6.8 7.8 1.6 6.7 5.4 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Hom_end_hint PF05203.11 EMG46132.1 - 1.6 8.4 8.0 1.9 8.1 5.5 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint IncA PF04156.9 EMG46132.1 - 1.7 8.1 12.2 2.1 7.9 8.5 1.0 1 0 0 1 1 1 0 IncA protein Dala_Dala_lig_N PF01820.16 EMG46132.1 - 1.8 8.9 4.8 2.3 8.5 3.3 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus SPOUT_MTase PF02590.12 EMG46132.1 - 1.9 8.1 6.9 2.5 7.8 4.8 1.2 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase GOLD_2 PF13897.1 EMG46132.1 - 2.1 8.5 5.5 2.9 8.1 3.8 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Presenilin PF01080.12 EMG46132.1 - 2.3 6.9 4.4 2.5 6.8 3.1 1.1 1 0 0 1 1 1 0 Presenilin Eapp_C PF10238.4 EMG46132.1 - 2.8 7.8 12.3 3.6 7.4 8.5 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein GAGA_bind PF06217.7 EMG46132.1 - 3.4 7.5 9.9 4 7.3 6.9 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Otopetrin PF03189.8 EMG46132.1 - 3.4 6.5 4.9 4.2 6.2 3.4 1.0 1 0 0 1 1 1 0 Otopetrin Paramyxo_ncap PF00973.14 EMG46132.1 - 3.6 6.1 9.4 4.2 5.9 6.5 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein RP-C_C PF11800.3 EMG46132.1 - 3.8 7.1 8.3 4.4 6.9 5.7 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region eIF_4EBP PF05456.6 EMG46132.1 - 4 7.1 6.9 5.6 6.6 4.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) NARP1 PF12569.3 EMG46132.1 - 4.4 5.9 11.9 4.8 5.8 8.2 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 HSP90 PF00183.13 EMG46132.1 - 5.7 5.2 16.5 6.4 5.0 11.4 1.0 1 0 0 1 1 1 0 Hsp90 protein Prog_receptor PF02161.10 EMG46132.1 - 6.4 5.4 7.3 6.9 5.3 5.1 1.0 1 0 0 1 1 1 0 Progesterone receptor Gti1_Pac2 PF09729.4 EMG46132.1 - 8.3 6.2 9.2 10 5.9 6.4 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family CobT PF06213.7 EMG46132.1 - 9.2 5.3 16.4 11 5.0 11.4 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RrnaAD PF00398.15 EMG46133.1 - 9e-63 211.7 0.0 1.2e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EMG46133.1 - 7.8e-10 38.8 0.0 1.2e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMG46133.1 - 4e-06 27.3 0.0 8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMG46133.1 - 0.00028 20.4 0.0 0.00047 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EMG46133.1 - 0.00084 18.4 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EMG46133.1 - 0.0018 17.6 0.0 0.0031 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 EMG46133.1 - 0.0032 17.0 0.0 0.0061 16.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.1 EMG46133.1 - 0.004 16.8 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMG46133.1 - 0.0063 16.1 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMG46133.1 - 0.0072 16.7 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EMG46133.1 - 0.051 12.7 0.0 0.11 11.6 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase Methyltransf_4 PF02390.12 EMG46133.1 - 0.069 12.1 0.1 0.32 10.0 0.0 1.8 1 1 1 2 2 2 0 Putative methyltransferase DREV PF05219.7 EMG46133.1 - 0.1 11.4 0.0 0.23 10.3 0.0 1.5 2 0 0 2 2 2 0 DREV methyltransferase Methyltransf_25 PF13649.1 EMG46133.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Kelch_3 PF13415.1 EMG46134.1 - 2.7e-38 129.2 4.2 5.8e-11 42.2 0.0 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EMG46134.1 - 1.9e-37 126.7 10.8 5.6e-08 32.4 0.0 7.1 5 3 1 6 6 6 6 Galactose oxidase, central domain DUF4110 PF13422.1 EMG46134.1 - 2.9e-27 94.3 0.0 2.9e-27 94.3 0.0 3.3 3 1 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.1 EMG46134.1 - 2.2e-23 81.4 5.8 5.9e-05 23.0 0.0 6.2 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.1 EMG46134.1 - 8.6e-22 76.6 5.1 0.00022 21.0 0.0 6.4 6 1 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 EMG46134.1 - 3.2e-12 45.7 15.7 0.0005 19.5 0.0 6.7 6 1 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 EMG46134.1 - 6.4e-10 38.3 14.3 0.13 12.0 0.0 6.6 6 1 0 6 6 6 4 Kelch motif DUF2724 PF10893.3 EMG46134.1 - 0.0038 17.0 0.3 0.024 14.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2724) Trypan_PARP PF05887.6 EMG46134.1 - 1.1 9.0 17.4 0.98 9.2 8.3 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) SH3_9 PF14604.1 EMG46135.1 - 1.7e-26 91.5 5.4 2.8e-13 49.2 0.5 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EMG46135.1 - 2.7e-26 90.6 8.9 2.2e-13 49.3 1.0 2.6 2 0 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.15 EMG46135.1 - 3.9e-19 68.7 0.0 6.9e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.12 EMG46135.1 - 1.9e-13 49.6 0.5 4.8e-06 25.9 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SPRY PF00622.23 EMG46136.1 - 2.7e-12 46.8 0.0 4.8e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 SPRY domain DPBB_1 PF03330.13 EMG46137.1 - 7.9e-10 38.6 0.0 2e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 EMG46137.1 - 0.0049 16.8 0.1 0.0083 16.1 0.0 1.4 1 0 0 1 1 1 1 Cerato-platanin DUF2076 PF09849.4 EMG46137.1 - 0.012 15.6 1.3 0.017 15.1 0.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Barwin PF00967.12 EMG46137.1 - 0.017 14.7 0.2 0.032 13.9 0.1 1.4 1 0 0 1 1 1 0 Barwin family SOG2 PF10428.4 EMG46137.1 - 5.1 5.6 8.3 6.6 5.2 5.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PIN_4 PF13638.1 EMG46138.1 - 1.3e-14 54.4 0.1 1.3e-14 54.4 0.0 2.9 3 0 0 3 3 3 1 PIN domain tRNA-synt_1b PF00579.20 EMG46139.1 - 2.5e-71 240.1 0.0 3e-71 239.9 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) zf-UBR PF02207.15 EMG46140.1 - 2.5e-16 59.1 14.1 2.5e-16 59.1 9.8 1.9 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EMG46140.1 - 3.4e-10 39.5 0.0 7.6e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_5 PF14634.1 EMG46140.1 - 0.00099 18.7 0.3 0.00099 18.7 0.2 3.1 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMG46140.1 - 0.0018 17.8 0.6 0.0018 17.8 0.4 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Sgf11 PF08209.6 EMG46140.1 - 0.057 12.7 1.8 0.13 11.5 0.4 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-UBR PF02207.15 EMG46141.1 - 6e-17 61.1 9.8 2.3e-16 59.2 6.8 2.1 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.1 EMG46141.1 - 0.0015 18.2 0.5 0.0015 18.2 0.3 3.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EMG46141.1 - 0.01 15.4 0.9 0.01 15.4 0.6 3.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ClpS PF02617.12 EMG46141.1 - 0.013 15.2 0.1 0.045 13.4 0.1 2.0 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS Mannosyl_trans3 PF11051.3 EMG46142.1 - 1.2e-76 257.6 0.0 2.1e-76 256.8 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative KH_dom-like PF14714.1 EMG46142.1 - 0.05 13.5 0.3 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Hyphal_reg_CWP PF11765.3 EMG46143.1 - 1.9e-53 181.3 7.4 2.1e-53 181.2 5.1 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Hyd_WA PF06462.7 EMG46143.1 - 0.07 12.7 0.0 0.95 9.1 0.0 2.4 2 0 0 2 2 2 0 Propeller LRR_8 PF13855.1 EMG46144.1 - 1.4e-14 53.5 38.5 3e-07 30.0 3.8 7.5 6 1 3 9 9 9 5 Leucine rich repeat LRR_4 PF12799.2 EMG46144.1 - 1.4e-11 43.7 56.3 1e-06 28.2 1.2 9.1 8 2 1 10 10 10 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMG46144.1 - 1.3e-08 33.6 33.7 0.0043 16.8 0.1 11.5 9 2 1 10 10 10 4 Leucine Rich Repeat LRR_6 PF13516.1 EMG46144.1 - 0.00029 20.5 34.4 0.31 11.2 0.1 10.3 8 1 2 10 10 10 4 Leucine Rich repeat LRR_7 PF13504.1 EMG46144.1 - 0.035 14.2 34.3 5.6 7.6 0.5 11.1 13 0 0 13 13 13 0 Leucine rich repeat FNIP PF05725.7 EMG46144.1 - 0.69 9.9 29.0 12 5.9 0.6 8.4 6 4 1 7 7 7 0 FNIP Repeat SDP_N PF12278.3 EMG46145.1 - 0.0085 15.7 6.5 0.0099 15.5 4.5 1.0 1 0 0 1 1 1 1 Sex determination protein N terminal Stap_Strp_toxin PF01123.15 EMG46145.1 - 0.068 13.6 3.4 0.074 13.5 2.3 1.1 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, OB-fold domain OB_NTP_bind PF07717.11 EMG46146.1 - 1.5e-26 92.4 0.0 3.9e-26 91.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EMG46146.1 - 5.3e-24 84.1 0.0 1.3e-23 82.8 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EMG46146.1 - 1.8e-12 46.9 0.0 5.8e-12 45.3 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMG46146.1 - 4.1e-07 29.6 0.2 1.2e-06 28.1 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EMG46146.1 - 5e-05 23.4 0.0 0.00029 20.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EMG46146.1 - 0.00015 21.2 0.1 0.00062 19.2 0.1 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 EMG46146.1 - 0.0045 16.8 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EMG46146.1 - 0.031 13.8 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 EMG46146.1 - 0.036 13.8 0.1 0.066 12.9 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain T2SE PF00437.15 EMG46146.1 - 0.045 12.6 0.0 0.086 11.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Vac14_Fab1_bd PF12755.2 EMG46147.1 - 0.034 14.5 14.1 0.2 12.0 0.1 4.8 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region Ribosomal_L30 PF00327.15 EMG46148.1 - 5.1e-17 61.1 0.6 1.4e-16 59.8 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Sulfatase PF00884.18 EMG46149.1 - 3.4e-65 220.2 0.0 5e-65 219.6 0.0 1.3 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 EMG46149.1 - 0.0005 18.6 0.0 0.00079 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.1 EMG46149.1 - 0.0018 18.5 0.0 0.053 13.8 0.0 2.3 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 EMG46149.1 - 0.025 13.9 0.1 0.29 10.4 0.0 2.2 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EMG46149.1 - 0.15 11.4 0.0 1.3 8.3 0.1 2.2 3 0 0 3 3 3 0 Metalloenzyme superfamily CorA PF01544.13 EMG46150.1 - 2.2e-44 151.6 2.8 2.2e-28 99.1 0.0 2.4 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF2183 PF09949.4 EMG46151.1 - 8.4e-32 109.0 0.1 3e-31 107.3 0.1 2.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) zf-CCCH PF00642.19 EMG46152.1 - 0.00051 19.6 2.8 0.00051 19.6 1.9 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Arf PF00025.16 EMG46153.1 - 9.2e-69 230.1 0.1 1e-68 230.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EMG46153.1 - 1.6e-13 50.1 1.7 3.4e-09 35.8 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EMG46153.1 - 1.7e-13 50.2 0.0 2e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EMG46153.1 - 1.1e-11 44.2 0.0 1.4e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EMG46153.1 - 2.3e-10 40.0 0.0 2.7e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EMG46153.1 - 3.6e-08 33.9 0.0 5.4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMG46153.1 - 1.4e-06 28.2 0.1 2e-06 27.7 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMG46153.1 - 0.0026 17.2 0.0 0.036 13.5 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EMG46153.1 - 0.004 16.2 0.1 0.0057 15.7 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase FeoB_N PF02421.13 EMG46153.1 - 0.16 11.2 0.8 1.1 8.5 0.6 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Rib_5-P_isom_A PF06026.9 EMG46154.1 - 1.3e-58 197.1 0.0 1.6e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 EMG46154.1 - 0.00046 19.8 0.0 0.3 10.7 0.0 2.2 1 1 1 2 2 2 2 DeoR C terminal sensor domain Ribosomal_S7e PF01251.13 EMG46155.1 - 9.1e-81 269.8 2.1 1.1e-80 269.6 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e SH3_9 PF14604.1 EMG46156.1 - 3.1e-26 90.7 0.2 1.1e-15 56.9 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EMG46156.1 - 1.4e-24 85.1 0.7 2e-12 46.2 0.1 2.5 2 0 0 2 2 2 2 SH3 domain FCH PF00611.18 EMG46156.1 - 6.2e-21 74.3 0.1 2.3e-20 72.5 0.1 2.1 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.12 EMG46156.1 - 2.8e-14 52.3 0.0 7.3e-08 31.7 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 EMG46156.1 - 0.0038 17.3 0.4 0.041 14.0 0.1 2.3 2 0 0 2 2 2 1 Bacterial SH3 domain Antitoxin-MazE PF04014.13 EMG46156.1 - 0.11 12.1 0.7 6.7 6.5 0.0 2.7 2 0 0 2 2 2 0 Antidote-toxin recognition MazE DUF3086 PF11285.3 EMG46156.1 - 0.15 10.8 7.9 0.057 12.2 1.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3086) Peroxidase_2 PF01328.12 EMG46157.1 - 0.041 12.5 2.9 0.038 12.6 2.0 1.0 1 0 0 1 1 1 0 Peroxidase, family 2 Fes1 PF08609.5 EMG46157.1 - 0.099 13.1 0.1 0.12 12.8 0.1 1.1 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 End3 PF12761.2 EMG46158.1 - 1.1e-74 250.3 8.7 1.5e-74 249.8 6.0 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 EMG46158.1 - 8.5e-54 179.6 1.9 4.3e-53 177.4 0.1 2.5 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EMG46158.1 - 2e-05 23.5 0.1 2e-05 23.5 0.1 2.9 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 EMG46158.1 - 9.4e-05 21.9 0.0 0.00029 20.3 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 EMG46158.1 - 0.014 15.4 0.0 0.014 15.4 0.0 3.3 4 0 0 4 4 4 0 EF-hand domain pair EF-hand_6 PF13405.1 EMG46158.1 - 0.017 14.9 0.1 0.017 14.9 0.1 3.3 3 0 0 3 3 3 0 EF-hand domain EF-hand_5 PF13202.1 EMG46158.1 - 0.021 14.1 0.2 0.021 14.1 0.1 3.1 3 0 0 3 3 3 0 EF hand Fib_alpha PF08702.5 EMG46158.1 - 0.89 9.6 11.0 1.5 8.8 7.6 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ADIP PF11559.3 EMG46158.1 - 1.1 9.1 13.6 3.9 7.3 9.4 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Complex1_30kDa PF00329.14 EMG46159.1 - 3.8e-36 123.4 0.0 5.9e-36 122.8 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit SCP2 PF02036.12 EMG46160.1 - 1.2e-22 80.1 2.5 1.4e-22 79.9 1.7 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EMG46160.1 - 6.8e-05 22.8 0.8 9.4e-05 22.3 0.5 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Toxin_R_bind_N PF07953.7 EMG46160.1 - 0.052 13.0 0.1 0.12 11.8 0.1 1.7 1 1 0 1 1 1 0 Clostridium neurotoxin, N-terminal receptor binding Dynein_heavy PF03028.10 EMG46161.1 - 0.17 9.8 5.1 0.2 9.6 3.5 1.1 1 0 0 1 1 1 0 Dynein heavy chain and region D6 of dynein motor MMS19_N PF14500.1 EMG46162.1 - 1e-86 290.4 4.1 1e-86 290.4 2.8 2.8 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 EMG46162.1 - 3.8e-71 239.9 29.2 3.8e-71 239.9 20.3 4.2 5 0 0 5 5 5 2 RNAPII transcription regulator C-terminal Ipi1_N PF12333.3 EMG46162.1 - 0.0033 17.3 1.0 0.13 12.2 0.0 3.7 4 1 0 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.17 EMG46162.1 - 0.11 12.6 0.1 7.2 6.9 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat NUC130_3NT PF08158.7 EMG46162.1 - 0.19 12.0 5.5 97 3.3 0.1 4.8 4 0 0 4 4 4 0 NUC130/3NT domain MOR2-PAG1_N PF14222.1 EMG46163.1 - 7.5e-148 493.6 12.2 1.2e-76 258.5 5.7 2.5 2 0 0 2 2 2 2 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EMG46163.1 - 4e-80 269.3 0.4 2.7e-79 266.6 0.1 2.5 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EMG46163.1 - 4.1e-29 100.8 13.3 1.3e-11 42.9 0.1 4.2 3 2 0 3 3 3 3 Cell morphogenesis central region HEAT PF02985.17 EMG46163.1 - 0.002 18.0 0.3 1.4 9.2 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat DUF2435 PF10363.4 EMG46163.1 - 0.0086 15.9 0.2 0.76 9.7 0.1 3.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) Troponin-I_N PF11636.3 EMG46164.1 - 0.011 15.4 3.0 0.011 15.4 2.1 3.5 4 0 0 4 4 4 0 Troponin I residues 1-32 DUF3812 PF12757.2 EMG46165.1 - 5.2e-28 97.5 9.8 5.2e-28 97.5 6.8 5.0 3 1 0 4 4 4 1 Protein of unknown function (DUF3812) HK97-gp10_like PF04883.7 EMG46166.1 - 0.096 13.6 0.3 0.096 13.6 0.2 2.1 1 1 1 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component DUF959 PF06121.9 EMG46166.1 - 0.43 10.1 10.2 0.44 10.1 7.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF959) DUF908 PF06012.7 EMG46166.1 - 2.4 7.3 9.5 2.8 7.1 6.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) MGC-24 PF05283.6 EMG46166.1 - 7.5 6.2 10.1 9.1 6.0 7.0 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Hid1 PF12722.2 EMG46166.1 - 9.4 3.7 8.6 10 3.6 5.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Grp1_Fun34_YaaH PF01184.14 EMG46167.1 - 3.4e-86 287.8 23.8 3.9e-86 287.6 16.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF373 PF04123.8 EMG46167.1 - 0.21 10.6 3.8 0.18 10.8 2.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF373) SQS_PSY PF00494.14 EMG46168.1 - 2.3e-20 72.9 0.0 2.8e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Spore_II_R PF09551.5 EMG46168.1 - 0.12 12.4 0.8 0.58 10.2 0.7 2.0 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) Pro_isomerase PF00160.16 EMG46169.1 - 1.9e-10 41.1 0.0 4e-10 40.1 0.0 1.5 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-RING_2 PF13639.1 EMG46170.1 - 2.7e-10 39.8 8.4 1.8e-09 37.2 2.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EMG46170.1 - 2.4e-08 33.9 4.4 1.4e-06 28.2 1.2 2.3 2 0 0 2 2 2 2 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMG46170.1 - 0.00024 20.7 7.8 0.00092 18.8 2.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMG46170.1 - 0.00046 19.8 7.6 0.0031 17.1 2.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMG46170.1 - 0.0017 18.3 5.7 0.0017 18.3 4.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMG46170.1 - 0.0033 17.0 8.1 0.0048 16.5 2.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMG46170.1 - 0.0074 16.1 2.1 0.026 14.3 0.8 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EMG46170.1 - 0.0074 15.9 1.1 0.0074 15.9 0.8 2.1 2 0 0 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.3 EMG46170.1 - 0.43 10.5 3.5 1.1 9.3 0.6 2.4 2 0 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EMG46170.1 - 4 7.4 8.6 0.52 10.2 3.0 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EMG46170.1 - 5.5 6.6 7.6 0.73 9.3 2.3 1.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit F-box-like PF12937.2 EMG46171.1 - 0.016 14.8 0.3 0.15 11.7 0.4 2.3 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 EMG46171.1 - 0.055 13.1 0.2 0.69 9.6 0.1 2.8 3 0 0 3 3 3 0 F-box domain PRANC PF09372.5 EMG46171.1 - 0.06 13.3 0.3 0.06 13.3 0.2 3.1 4 0 0 4 4 4 0 PRANC domain LRR_2 PF07723.8 EMG46171.1 - 0.24 11.9 3.9 9.6 6.8 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat DUF1358 PF07096.6 EMG46172.1 - 0.0044 16.6 0.1 0.0055 16.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) Lon_C PF05362.8 EMG46173.1 - 6.3e-43 146.4 0.0 1.1e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EMG46173.1 - 7.2e-26 91.1 4.3 1.4e-25 90.1 1.0 2.5 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EMG46173.1 - 1e-23 83.9 0.0 2.8e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMG46173.1 - 1.6e-07 31.1 0.0 4.1e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EMG46173.1 - 1.6e-06 28.1 0.0 3.8e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EMG46173.1 - 5.5e-06 27.1 0.5 7.1e-05 23.6 0.0 3.0 2 1 0 2 2 1 1 AAA domain ChlI PF13541.1 EMG46173.1 - 1.6e-05 24.3 0.0 3.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 EMG46173.1 - 5.3e-05 23.2 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EMG46173.1 - 0.00013 21.8 0.0 0.00097 19.0 0.0 2.6 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EMG46173.1 - 0.00019 21.1 0.0 0.00043 19.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 EMG46173.1 - 0.00021 20.4 0.0 0.00048 19.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 EMG46173.1 - 0.00033 20.7 0.0 0.018 15.1 0.0 2.9 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EMG46173.1 - 0.00061 19.4 0.0 0.0016 18.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EMG46173.1 - 0.00079 18.5 0.0 0.002 17.2 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EMG46173.1 - 0.0019 18.0 0.0 0.0045 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMG46173.1 - 0.0024 18.1 4.0 0.0033 17.7 0.0 3.3 3 0 0 3 3 2 1 AAA domain UPF0079 PF02367.12 EMG46173.1 - 0.0026 17.3 0.0 0.0087 15.6 0.0 1.9 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 EMG46173.1 - 0.0051 15.5 0.0 0.018 13.8 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus Dscam_C PF12355.3 EMG46173.1 - 0.0082 16.4 0.8 0.0082 16.4 0.5 1.9 2 0 0 2 2 1 1 Down syndrome cell adhesion molecule C terminal IstB_IS21 PF01695.12 EMG46173.1 - 0.015 14.6 0.0 0.037 13.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 EMG46173.1 - 0.019 15.1 0.0 0.083 13.0 0.0 2.2 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 EMG46173.1 - 0.024 14.0 0.0 0.069 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EMG46173.1 - 0.028 13.5 0.0 0.07 12.2 0.0 1.6 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EMG46173.1 - 0.029 14.0 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.11 EMG46173.1 - 0.034 13.3 0.0 0.09 11.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein MobB PF03205.9 EMG46173.1 - 0.073 12.7 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EMG46173.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EMG46173.1 - 0.14 12.1 0.1 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Striatin PF08232.7 EMG46173.1 - 0.73 10.1 8.8 1.1 9.6 1.9 2.7 2 0 0 2 2 2 0 Striatin family PBP1_TM PF14812.1 EMG46173.1 - 2 8.7 8.4 0.17 12.2 1.4 2.5 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Asp PF00026.18 EMG46174.1 - 2.3e-60 204.5 8.6 3.2e-60 204.0 5.9 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMG46174.1 - 1.6e-07 31.3 0.3 1e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMG46174.1 - 0.00047 20.6 2.5 3.5 8.1 0.0 4.0 4 0 0 4 4 4 2 Aspartyl protease TAXi_C PF14541.1 EMG46174.1 - 0.0039 16.7 0.0 0.11 12.0 0.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DUF663 PF04950.7 EMG46175.1 - 9.7e-98 326.7 0.3 9.7e-98 326.7 0.2 3.5 4 0 0 4 4 3 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EMG46175.1 - 1.1e-29 101.7 0.0 4.9e-28 96.4 0.0 2.9 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EMG46175.1 - 5.2e-08 32.5 0.0 4.3e-05 23.0 0.0 2.8 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA PF00004.24 EMG46175.1 - 4.2e-06 26.9 0.0 1.2e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EMG46175.1 - 1.3e-05 25.1 0.0 5e-05 23.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMG46175.1 - 3e-05 24.8 0.0 3e-05 24.8 0.0 5.3 4 2 1 5 5 2 1 AAA domain AAA_16 PF13191.1 EMG46175.1 - 4.5e-05 23.5 0.0 0.00012 22.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 EMG46175.1 - 7.8e-05 22.4 1.1 0.00021 21.0 0.2 2.2 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EMG46175.1 - 0.00015 21.4 0.1 0.00038 20.1 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EMG46175.1 - 0.00024 21.2 0.0 0.00094 19.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EMG46175.1 - 0.0005 20.3 1.8 0.0019 18.4 0.0 2.8 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.17 EMG46175.1 - 0.00063 19.8 0.2 0.0027 17.8 0.0 2.2 2 0 0 2 2 1 1 RNA helicase MMR_HSR1 PF01926.18 EMG46175.1 - 0.00075 19.4 0.4 0.0039 17.1 0.3 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMG46175.1 - 0.00079 19.9 0.8 0.0031 18.0 0.0 2.5 2 0 0 2 2 1 1 Miro-like protein NTPase_1 PF03266.10 EMG46175.1 - 0.0035 17.0 0.1 0.01 15.5 0.1 1.8 1 0 0 1 1 1 1 NTPase AAA_5 PF07728.9 EMG46175.1 - 0.0069 16.1 0.1 0.021 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EMG46175.1 - 0.01 15.2 0.0 0.028 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EMG46175.1 - 0.014 14.8 0.0 0.033 13.6 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EMG46175.1 - 0.017 14.7 0.1 0.047 13.3 0.1 1.8 1 1 0 1 1 1 0 NACHT domain ArgK PF03308.11 EMG46175.1 - 0.063 12.0 0.0 0.063 12.0 0.0 2.0 2 0 0 2 2 2 0 ArgK protein Adeno_IVa2 PF02456.10 EMG46175.1 - 0.11 11.1 0.5 0.26 9.8 0.0 1.7 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_29 PF13555.1 EMG46175.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_11 PF13086.1 EMG46175.1 - 0.11 11.9 0.0 0.11 11.9 0.0 3.6 3 1 0 3 3 2 0 AAA domain Viral_helicase1 PF01443.13 EMG46175.1 - 0.19 11.2 1.1 0.26 10.7 0.0 1.8 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase Transket_pyr PF02779.19 EMG46177.1 - 2.5e-65 219.2 0.0 4.4e-65 218.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EMG46177.1 - 9.3e-60 201.8 0.0 1.3e-59 201.3 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF4572 PF15139.1 EMG46177.1 - 0.0095 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4572) DUF676 PF05057.9 EMG46178.1 - 9.1e-48 162.4 0.0 2e-47 161.3 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 EMG46178.1 - 0.0035 16.3 0.3 0.01 14.8 0.1 1.8 1 1 1 2 2 2 1 Lecithin:cholesterol acyltransferase Lipase PF00151.14 EMG46178.1 - 0.0091 15.2 0.0 0.0091 15.2 0.0 1.9 2 0 0 2 2 2 1 Lipase Lipase_3 PF01764.20 EMG46178.1 - 0.01 15.4 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 EMG46178.1 - 0.02 14.5 0.2 0.073 12.6 0.0 1.9 1 1 1 2 2 2 0 PGAP1-like protein Abhydrolase_5 PF12695.2 EMG46178.1 - 0.025 14.3 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMG46178.1 - 0.058 12.9 0.5 7 6.1 0.0 2.7 3 0 0 3 3 3 0 alpha/beta hydrolase fold Senescence_reg PF04520.8 EMG46178.1 - 0.75 10.2 4.5 1.6 9.2 3.1 1.6 1 0 0 1 1 1 0 Senescence regulator adh_short PF00106.20 EMG46179.1 - 6.7e-23 81.4 0.0 8.9e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMG46179.1 - 1.5e-10 41.2 0.0 2.3e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EMG46179.1 - 1.7e-06 27.3 0.0 0.0006 19.0 0.0 2.6 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EMG46179.1 - 1.2e-05 25.3 0.0 2.4e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EMG46179.1 - 8.2e-05 22.3 0.3 0.00058 19.6 0.1 2.3 3 0 0 3 3 3 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.5 EMG46179.1 - 9.1e-05 22.1 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMG46179.1 - 0.0035 16.7 0.0 0.027 13.9 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ParBc PF02195.13 EMG46179.1 - 0.11 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 ParB-like nuclease domain LRR_4 PF12799.2 EMG46183.1 - 6.9e-25 86.1 84.8 4.3e-07 29.4 0.6 12.4 5 3 5 11 11 11 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG46183.1 - 1.4e-11 43.9 70.7 0.00062 19.4 10.0 10.2 5 3 5 11 11 11 7 Leucine rich repeat LRR_1 PF00560.28 EMG46183.1 - 2.8e-10 38.7 79.3 0.25 11.5 0.3 17.9 17 4 1 18 18 18 7 Leucine Rich Repeat LRR_7 PF13504.1 EMG46183.1 - 3.8e-07 29.2 51.2 1.2 9.6 0.1 16.1 19 1 0 19 19 19 4 Leucine rich repeat LRR_6 PF13516.1 EMG46183.1 - 1.1e-05 24.9 74.2 1.8 8.8 0.0 16.8 17 1 0 17 17 17 6 Leucine Rich repeat Rtt106 PF08512.7 EMG46183.1 - 0.23 11.4 2.8 3.5 7.6 0.1 2.8 2 0 0 2 2 2 0 Histone chaperone Rttp106-like FNIP PF05725.7 EMG46183.1 - 0.33 10.9 43.7 0.096 12.6 0.5 9.1 7 3 0 7 7 7 0 FNIP Repeat LRR_9 PF14580.1 EMG46183.1 - 4.7 6.7 12.6 3.3 7.2 0.2 3.6 3 1 0 3 3 3 0 Leucine-rich repeat Fer2 PF00111.22 EMG46184.1 - 1.4e-14 53.5 0.4 1.8e-14 53.2 0.3 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.1 EMG46184.1 - 0.17 11.7 1.0 0.53 10.1 0.7 1.8 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain V-SNARE_C PF12352.3 EMG46185.1 - 1.1e-19 70.2 7.3 1.1e-19 70.2 5.1 2.7 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 EMG46185.1 - 4.7e-14 52.2 5.6 4.7e-14 52.2 3.9 3.4 2 2 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus DUF106 PF01956.11 EMG46185.1 - 0.016 14.7 0.0 0.046 13.2 0.0 1.9 1 1 0 1 1 1 0 Integral membrane protein DUF106 DUF4407 PF14362.1 EMG46185.1 - 0.017 14.0 1.2 0.023 13.6 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sec20 PF03908.8 EMG46185.1 - 0.024 14.3 7.3 0.061 13.0 0.7 2.7 2 2 1 3 3 3 0 Sec20 CENP-H PF05837.7 EMG46185.1 - 0.037 14.1 2.5 0.037 14.1 1.7 2.3 2 1 0 2 2 2 0 Centromere protein H (CENP-H) YqjK PF13997.1 EMG46185.1 - 0.044 13.9 1.9 0.081 13.0 0.0 2.3 3 0 0 3 3 3 0 YqjK-like protein Use1 PF09753.4 EMG46185.1 - 0.053 12.9 6.8 0.65 9.3 4.7 2.6 1 1 0 1 1 1 0 Membrane fusion protein Use1 Flu_NS2 PF00601.14 EMG46185.1 - 0.065 13.4 0.2 0.22 11.7 0.2 1.9 1 1 0 1 1 1 0 Influenza non-structural protein (NS2) DUF1640 PF07798.6 EMG46185.1 - 0.069 13.1 6.1 2.2 8.2 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) DUF3150 PF11348.3 EMG46185.1 - 0.12 11.5 2.7 0.64 9.0 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3150) Myosin_tail_1 PF01576.14 EMG46185.1 - 0.13 9.9 9.5 0.5 8.0 2.1 2.0 2 0 0 2 2 2 0 Myosin tail Prefoldin_2 PF01920.15 EMG46185.1 - 0.14 11.9 7.6 0.81 9.4 0.3 3.2 2 1 1 3 3 3 0 Prefoldin subunit Tup_N PF08581.5 EMG46185.1 - 0.42 10.8 4.8 0.31 11.2 0.7 2.5 2 1 1 3 3 3 0 Tup N-terminal Fusion_gly PF00523.13 EMG46185.1 - 0.43 8.5 8.0 0.16 9.9 0.7 2.3 2 1 1 3 3 3 0 Fusion glycoprotein F0 GP41 PF00517.12 EMG46185.1 - 0.45 10.0 5.2 0.13 11.8 0.2 2.2 2 1 0 2 2 2 0 Retroviral envelope protein Spc7 PF08317.6 EMG46185.1 - 1.4 7.5 11.3 1.3 7.6 6.7 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein FliJ PF02050.11 EMG46185.1 - 1.5 8.8 15.5 1.7 8.7 3.2 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein Prefoldin PF02996.12 EMG46185.1 - 2 8.0 6.9 9.1 5.9 0.1 3.3 3 0 0 3 3 3 0 Prefoldin subunit Mnd1 PF03962.10 EMG46185.1 - 7.3 6.2 10.2 1.9 8.1 1.7 2.1 1 1 0 2 2 2 0 Mnd1 family DUF4618 PF15397.1 EMG46185.1 - 9.7 5.4 11.2 1.2 8.4 2.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) TAFII28 PF04719.9 EMG46186.1 - 2.3e-21 75.4 2.4 3.1e-19 68.5 0.9 2.3 2 0 0 2 2 2 2 hTAFII28-like protein conserved region LrgB PF04172.11 EMG46186.1 - 0.08 12.0 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 LrgB-like family Nop14 PF04147.7 EMG46186.1 - 3 5.6 23.1 4.3 5.1 16.0 1.2 1 0 0 1 1 1 0 Nop14-like family AA_permease PF00324.16 EMG46187.1 - 1.1e-98 330.6 41.4 1.4e-98 330.3 28.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG46187.1 - 9.4e-32 110.0 44.6 1.3e-31 109.6 30.9 1.2 1 0 0 1 1 1 1 Amino acid permease Phtf-FEM1B_bdg PF12129.3 EMG46187.1 - 5.9 6.2 10.9 11 5.2 0.4 2.4 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor DUF3533 PF12051.3 EMG46188.1 - 3e-102 342.2 17.2 3.6e-102 341.9 11.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Transp_cyt_pur PF02133.10 EMG46189.1 - 3.3e-44 151.1 29.2 4e-44 150.8 20.2 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ABC2_membrane_5 PF13346.1 EMG46189.1 - 6.4 6.0 35.3 0.011 15.1 5.9 3.4 2 1 0 3 3 3 0 ABC-2 family transporter protein DUF3533 PF12051.3 EMG46190.1 - 1.3e-118 396.0 16.5 1.5e-118 395.8 11.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Glyco_hydro_63 PF03200.11 EMG46191.1 - 1.3e-07 29.9 7.9 1.5e-05 23.0 0.3 3.7 3 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase UDPGT PF00201.13 EMG46191.1 - 0.067 11.7 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase TMA7 PF09072.5 EMG46191.1 - 0.13 12.7 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 Translation machinery associated TMA7 TRP PF06011.7 EMG46192.1 - 1.3e-137 459.0 30.9 1.3e-137 459.0 21.4 1.4 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EMG46192.1 - 1.4e-46 158.0 0.9 1.4e-46 158.0 0.6 1.7 2 0 0 2 2 2 1 ML-like domain DUF4410 PF14366.1 EMG46192.1 - 0.023 14.4 1.3 0.045 13.4 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) ABC_tran PF00005.22 EMG46193.1 - 5.4e-58 195.1 0.0 3.1e-34 118.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EMG46193.1 - 7.5e-48 163.3 34.9 1.1e-28 100.4 9.1 3.6 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 EMG46193.1 - 3.2e-09 37.1 4.4 0.00029 20.9 0.3 4.2 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EMG46193.1 - 5.9e-09 36.5 6.3 7.6e-05 23.1 0.1 3.6 4 0 0 4 4 3 2 AAA domain SMC_N PF02463.14 EMG46193.1 - 4.3e-08 32.6 2.8 0.0046 16.2 0.6 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EMG46193.1 - 2e-06 27.2 0.1 0.0058 16.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EMG46193.1 - 2.7e-06 26.6 0.0 0.036 13.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EMG46193.1 - 0.00012 21.5 0.0 0.037 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EMG46193.1 - 0.00015 21.6 0.1 0.023 14.6 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EMG46193.1 - 0.00016 22.1 0.2 0.39 11.2 0.0 3.2 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 EMG46193.1 - 0.00051 20.0 0.2 0.23 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EMG46193.1 - 0.0011 19.7 0.6 0.36 11.6 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EMG46193.1 - 0.0026 17.8 0.2 2.6 8.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 EMG46193.1 - 0.0027 16.8 0.2 2.3 7.2 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin T2SE PF00437.15 EMG46193.1 - 0.01 14.7 0.0 3.3 6.5 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ArgK PF03308.11 EMG46193.1 - 0.017 13.9 0.1 0.029 13.1 0.0 1.3 1 0 0 1 1 1 0 ArgK protein MobB PF03205.9 EMG46193.1 - 0.022 14.4 0.4 2.2 7.9 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EMG46193.1 - 0.034 13.7 0.2 8.7 5.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EMG46193.1 - 0.05 13.0 0.0 3.3 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain UPF0079 PF02367.12 EMG46193.1 - 0.078 12.6 4.6 1 8.9 0.1 3.8 4 0 0 4 4 4 0 Uncharacterised P-loop hydrolase UPF0079 Dynamin_N PF00350.18 EMG46193.1 - 0.082 12.7 0.5 8.9 6.0 0.0 2.9 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.1 EMG46193.1 - 0.095 13.0 0.3 7.5 6.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EMG46193.1 - 0.12 11.9 0.0 20 4.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EMG46193.1 - 0.16 11.0 0.0 2.8 7.0 0.0 2.5 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 EMG46193.1 - 0.16 12.1 1.0 35 4.6 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EMG46193.1 - 0.18 11.2 0.0 2.5 7.5 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.14 EMG46193.1 - 0.61 9.5 4.0 7.5 5.9 0.6 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 EMG46193.1 - 0.85 9.3 4.7 0.49 10.1 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF87 RRM_1 PF00076.17 EMG46194.1 - 1e-24 85.8 13.6 1.5e-14 53.3 3.2 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG46194.1 - 6e-20 71.0 2.9 5.4e-13 48.7 0.2 2.5 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG46194.1 - 1.5e-15 56.7 1.7 1.7e-08 34.1 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EMG46194.1 - 0.02 14.6 4.6 0.67 9.7 0.2 2.8 2 2 0 2 2 2 0 Limkain b1 BRAP2 PF07576.7 EMG46194.1 - 2.3 7.8 4.4 4.8 6.8 0.5 2.5 2 0 0 2 2 2 0 BRCA1-associated protein 2 FAM165 PF14981.1 EMG46194.1 - 3.8 7.0 8.5 15 5.1 5.9 2.1 1 0 0 1 1 1 0 FAM165 family PcfK PF14058.1 EMG46194.1 - 4.4 7.4 14.0 1 9.5 2.8 2.4 2 0 0 2 2 2 0 PcfK-like protein Carn_acyltransf PF00755.15 EMG46195.1 - 1.1e-88 297.8 0.2 1.6e-88 297.3 0.1 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase RVT_1 PF00078.22 EMG46196.1 - 5.9e-23 81.3 0.2 1.3e-22 80.1 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 EMG46196.1 - 0.00096 19.1 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Hydrolase_like2 PF13246.1 EMG46198.1 - 1.7e-13 50.2 0.1 5.3e-13 48.7 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 EMG46198.1 - 6.7e-13 48.1 0.0 6.7e-13 48.1 0.0 2.1 3 0 0 3 3 3 1 E1-E2 ATPase HAD PF12710.2 EMG46198.1 - 1.4e-12 48.1 0.1 4.1e-12 46.6 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMG46198.1 - 4.7e-12 46.7 0.2 9.8e-06 26.1 0.0 3.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMG46198.1 - 0.0024 17.4 4.9 0.038 13.5 3.4 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Apc1 PF12859.2 EMG46198.1 - 0.18 12.0 0.5 16 5.7 0.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 CPSF100_C PF13299.1 EMG46199.1 - 3.7e-33 115.0 0.0 3.7e-33 115.0 0.0 3.4 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EMG46199.1 - 1.4e-17 63.8 0.0 7.2e-17 61.5 0.0 2.3 2 0 0 2 2 2 1 Beta-Casp domain Ndufs5 PF10200.4 EMG46199.1 - 1.7e-06 27.9 1.1 1.4e-05 25.0 0.3 2.6 2 0 0 2 2 2 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Alg14 PF08660.6 EMG46199.1 - 0.044 13.7 0.3 0.31 11.0 0.0 2.5 3 0 0 3 3 3 0 Oligosaccharide biosynthesis protein Alg14 like CHCH PF06747.8 EMG46199.1 - 4.8 7.2 5.7 22 5.1 0.7 2.3 1 1 1 2 2 2 0 CHCH domain NPR2 PF06218.6 EMG46201.1 - 6.9e-181 601.6 15.0 3.4e-180 599.3 8.6 2.0 2 0 0 2 2 2 2 Nitrogen permease regulator 2 Sigma70_ner PF04546.8 EMG46201.1 - 0.051 13.1 10.9 0.048 13.2 3.8 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region NPR3 PF03666.8 EMG46201.1 - 0.1 11.0 0.0 0.1 11.0 0.0 3.7 2 2 1 4 4 4 0 Nitrogen Permease regulator of amino acid transport activity 3 Astro_capsid PF03115.9 EMG46201.1 - 0.18 10.0 1.4 0.29 9.3 1.0 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor KH_1 PF00013.24 EMG46202.1 - 7.5e-07 28.7 0.0 1.5e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EMG46202.1 - 2.3e-06 27.1 1.7 3.2e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 KH domain zf-CCHC PF00098.18 EMG46202.1 - 3.8e-05 23.3 0.8 6.6e-05 22.6 0.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EMG46202.1 - 0.0064 16.2 0.3 0.015 15.0 0.2 1.6 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.3 EMG46202.1 - 0.014 15.2 1.0 0.044 13.7 0.1 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_4 PF14392.1 EMG46202.1 - 0.19 11.4 1.2 0.35 10.5 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle Methyltransf_26 PF13659.1 EMG46203.1 - 8.9e-13 48.3 0.0 1.2e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMG46203.1 - 1.9e-09 37.1 0.0 2.4e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EMG46203.1 - 1.9e-07 30.7 0.0 3.3e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMG46203.1 - 0.00093 18.2 0.2 0.0018 17.3 0.1 1.4 2 0 0 2 2 2 1 Putative methyltransferase DUF938 PF06080.7 EMG46203.1 - 0.0011 18.5 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_16 PF10294.4 EMG46203.1 - 0.003 17.0 0.1 0.0094 15.4 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.8 EMG46203.1 - 0.0038 16.3 0.4 0.023 13.8 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 EMG46203.1 - 0.0082 16.5 0.1 0.025 15.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMG46203.1 - 0.0083 16.5 0.0 0.022 15.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 EMG46203.1 - 0.014 15.0 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein DUF2431 PF10354.4 EMG46203.1 - 0.038 13.9 0.0 0.12 12.3 0.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF2431) Methyltransf_18 PF12847.2 EMG46203.1 - 0.061 13.9 0.0 0.11 13.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.5 EMG46203.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit TPR_14 PF13428.1 EMG46204.1 - 2e-11 43.4 0.0 1.5 9.6 0.0 8.1 6 2 3 9 9 9 3 Tetratricopeptide repeat HAT PF02184.11 EMG46204.1 - 1.1e-09 37.8 35.5 0.0036 17.0 0.0 9.9 10 1 1 11 11 11 5 HAT (Half-A-TPR) repeat Suf PF05843.9 EMG46204.1 - 2.1e-09 37.5 24.2 2.5e-06 27.4 0.6 5.6 3 2 1 4 4 4 3 Suppressor of forked protein (Suf) TPR_16 PF13432.1 EMG46204.1 - 7.7e-07 29.6 0.0 0.17 12.6 0.0 4.6 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMG46204.1 - 1.1e-06 28.8 0.0 0.0048 17.2 0.0 5.1 4 2 1 5 5 5 2 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EMG46204.1 - 0.055 13.2 0.2 0.055 13.2 0.2 6.4 3 2 3 6 6 6 0 U3 small nucleolar RNA-associated protein 6 Histone PF00125.19 EMG46205.1 - 7.5e-23 80.4 0.1 9.4e-23 80.1 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMG46205.1 - 0.00011 22.1 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone OPA3 PF07047.7 EMG46206.1 - 4.3e-34 117.1 1.7 6.4e-34 116.6 1.2 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) HR1 PF02185.11 EMG46206.1 - 0.038 13.7 0.1 0.08 12.6 0.0 1.6 1 0 0 1 1 1 0 Hr1 repeat DUF4343 PF14243.1 EMG46206.1 - 0.12 12.2 0.1 0.29 10.9 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4343) IU_nuc_hydro PF01156.14 EMG46207.1 - 4.2e-40 137.9 0.0 4.9e-40 137.6 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Pkinase PF00069.20 EMG46208.1 - 9.6e-57 192.0 3.3 1.7e-56 191.3 2.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG46208.1 - 1.9e-30 105.7 2.0 1.5e-29 102.8 1.4 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG46208.1 - 4.4e-05 22.5 0.0 8.7e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Blo-t-5 PF11642.3 EMG46208.1 - 0.21 11.3 0.0 0.21 11.3 0.0 2.9 2 1 1 3 3 3 0 Mite allergen Blo t 5 TMEM171 PF15471.1 EMG46208.1 - 1.1 7.9 6.1 2.4 6.8 4.2 1.5 1 0 0 1 1 1 0 Transmembrane protein family 171 Ank_4 PF13637.1 EMG46209.1 - 6.1e-17 61.6 3.4 2.8e-06 27.6 0.0 4.6 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMG46209.1 - 7.6e-13 47.3 0.6 0.00048 20.1 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 EMG46209.1 - 1e-12 48.2 1.0 1.2e-06 28.7 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMG46209.1 - 1.6e-11 43.3 0.1 0.00029 20.5 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EMG46209.1 - 2.3e-11 43.5 0.7 4.5e-06 26.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.8 EMG46209.1 - 1.1e-06 28.2 1.0 9.5e-06 25.2 0.0 3.1 2 1 0 2 2 2 1 KilA-N domain DUF682 PF05081.7 EMG46210.1 - 0.012 15.1 0.3 0.029 13.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF682) DUF2296 PF10058.4 EMG46211.1 - 4e-22 77.7 0.2 7.9e-22 76.7 0.1 1.5 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) Pro-rich PF15240.1 EMG46211.1 - 0.14 12.2 29.4 0.4 10.7 20.3 2.0 1 1 0 1 1 1 0 Proline-rich Dynein_heavy PF03028.10 EMG46211.1 - 0.19 9.7 5.0 0.29 9.0 3.5 1.2 1 0 0 1 1 1 0 Dynein heavy chain and region D6 of dynein motor DUF3735 PF12537.3 EMG46211.1 - 0.21 11.6 2.0 12 6.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3735) DivIC PF04977.10 EMG46211.1 - 0.39 10.2 0.1 0.39 10.2 0.0 2.6 3 0 0 3 3 3 0 Septum formation initiator DUF1043 PF06295.7 EMG46211.1 - 0.91 9.1 10.1 0.28 10.8 4.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF3729 PF12526.3 EMG46211.1 - 3.8 8.8 14.8 0.76 11.1 4.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) NAC PF01849.13 EMG46212.1 - 4.2e-19 67.8 0.4 5.1e-18 64.3 0.0 2.2 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EMG46212.1 - 1.5e-05 24.7 1.1 1.8e-05 24.4 0.1 1.7 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 EMG46212.1 - 0.046 13.2 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain RNA_pol_Rpo13 PF12136.3 EMG46212.1 - 0.055 13.1 6.1 0.13 11.9 4.2 1.5 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain BNIP3 PF06553.7 EMG46212.1 - 0.14 11.5 1.5 0.19 11.0 1.0 1.2 1 0 0 1 1 1 0 BNIP3 Presenilin PF01080.12 EMG46212.1 - 0.71 8.6 2.2 0.94 8.2 1.5 1.2 1 0 0 1 1 1 0 Presenilin Hist_deacetyl PF00850.14 EMG46213.1 - 9.3e-81 271.4 0.0 1.3e-80 271.0 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Proteasome PF00227.21 EMG46214.1 - 1.4e-43 148.3 0.2 1.8e-43 148.0 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMG46214.1 - 1.4e-14 53.0 0.1 2.5e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ERG4_ERG24 PF01222.12 EMG46215.1 - 2.8e-155 517.0 26.5 3.3e-155 516.8 18.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF2207 PF09972.4 EMG46215.1 - 7 5.1 6.4 12 4.3 1.3 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) FAM220 PF15487.1 EMG46216.1 - 0.024 13.9 0.5 0.032 13.6 0.3 1.2 1 0 0 1 1 1 0 FAM220 family Claudin_2 PF13903.1 EMG46216.1 - 0.21 11.2 0.6 0.31 10.7 0.4 1.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Pyr_redox_2 PF07992.9 EMG46217.1 - 1.7e-26 93.3 0.8 3.5e-16 59.7 0.0 3.5 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMG46217.1 - 4e-11 43.1 0.1 1.4e-09 38.2 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMG46217.1 - 5e-05 23.4 0.1 0.019 14.9 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMG46217.1 - 0.046 12.6 0.0 8.1 5.2 0.0 2.5 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Med10 PF09748.4 EMG46217.1 - 0.065 13.0 0.2 0.24 11.2 0.1 2.0 2 1 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex Mod_r PF07200.8 EMG46218.1 - 9.7e-09 35.3 18.7 1.3e-08 34.8 13.0 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Cep57_MT_bd PF06657.8 EMG46218.1 - 0.00019 21.3 1.3 0.00019 21.3 0.9 1.8 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 DUF2937 PF11157.3 EMG46218.1 - 0.035 13.4 2.6 4.4 6.6 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) Lge1 PF11488.3 EMG46218.1 - 0.39 10.9 5.1 18 5.5 3.5 2.7 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 Syntaxin_2 PF14523.1 EMG46218.1 - 1.3 9.0 19.2 1 9.4 11.2 2.1 1 1 1 2 2 2 0 Syntaxin-like protein PMC2NT PF08066.7 EMG46218.1 - 1.5 9.2 6.3 3.6 7.9 0.2 2.3 2 0 0 2 2 2 0 PMC2NT (NUC016) domain DUF2120 PF09893.4 EMG46218.1 - 3.8 7.4 10.1 0.47 10.3 2.2 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) UPF0118 PF01594.11 EMG46218.1 - 5.7 5.8 6.3 2.5 7.0 2.8 1.5 1 1 1 2 2 2 0 Domain of unknown function DUF20 PHA_synth_III_E PF09712.5 EMG46218.1 - 8.2 5.7 9.6 4.4 6.6 4.0 1.9 1 1 1 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) MFS_1 PF07690.11 EMG46219.1 - 6.3e-42 143.5 25.9 2.9e-39 134.8 18.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3589 PF12141.3 EMG46220.1 - 5.4e-138 460.3 0.1 7e-138 459.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3589) Chitin_synth_1 PF01644.12 EMG46221.1 - 4.7e-66 221.5 0.1 7.6e-66 220.9 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EMG46221.1 - 4.8e-26 90.2 0.5 1.1e-25 89.1 0.3 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EMG46221.1 - 1e-19 70.3 1.5 1.5e-16 59.8 0.0 2.9 3 1 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EMG46221.1 - 5.7e-15 55.5 1.6 3.3e-14 53.0 1.1 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMG46221.1 - 1.2e-12 48.1 0.0 3.6e-12 46.5 0.0 1.8 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EMG46221.1 - 0.0012 18.1 0.0 0.014 14.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 Vps8 PF12816.2 EMG46222.1 - 2.1e-57 193.5 9.0 2.4e-57 193.3 4.8 2.4 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 WD40 PF00400.27 EMG46222.1 - 0.00041 20.1 0.1 0.0042 16.9 0.0 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat zf-RING_5 PF14634.1 EMG46222.1 - 0.033 13.9 0.3 0.11 12.2 0.2 1.9 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 EMG46222.1 - 0.15 11.9 0.7 0.78 9.6 0.5 2.3 1 0 0 1 1 1 0 Ring finger domain FNIP PF05725.7 EMG46223.1 - 0.054 13.4 14.1 3.6 7.6 0.1 6.8 6 1 0 6 6 6 0 FNIP Repeat DUF2457 PF10446.4 EMG46223.1 - 0.51 9.0 15.2 0.78 8.3 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.8 EMG46223.1 - 0.64 9.6 9.3 1.3 8.6 6.5 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Rhabdo_ncap PF00945.13 EMG46223.1 - 0.91 8.0 4.8 1.6 7.2 3.4 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Nucleoplasmin PF03066.10 EMG46223.1 - 5.6 6.4 11.7 10 5.5 8.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 EMG46223.1 - 7.9 4.3 9.1 12 3.8 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein adh_short PF00106.20 EMG46225.1 - 3.3e-70 235.3 2.3 3.5e-36 124.6 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EMG46225.1 - 2.5e-36 125.0 0.2 2.3e-17 63.2 0.0 2.2 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 EMG46225.1 - 2.4e-30 104.4 0.0 5.3e-30 103.3 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain adh_short_C2 PF13561.1 EMG46225.1 - 2.4e-21 76.6 0.5 5.7e-11 42.6 0.0 3.0 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Nucleoplasmin PF03066.10 EMG46225.1 - 0.45 10.0 7.8 0.91 9.0 5.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 EMG46225.1 - 1.2 7.5 4.3 1.8 6.9 3.0 1.1 1 0 0 1 1 1 0 Daxx Family Sigma70_ner PF04546.8 EMG46225.1 - 1.7 8.1 7.3 3.1 7.3 5.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Myc_N PF01056.13 EMG46225.1 - 4.5 6.3 8.6 7.4 5.6 5.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF2457 PF10446.4 EMG46225.1 - 9 4.8 9.0 14 4.3 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Rhodanese PF00581.15 EMG46226.1 - 1.8e-13 50.8 0.0 4.3e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain CENP-B_dimeris PF09026.5 EMG46226.1 - 6.3 7.1 13.2 2.2 8.5 1.9 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain E1-E2_ATPase PF00122.15 EMG46227.1 - 1.7e-62 210.4 7.4 2.9e-62 209.6 5.1 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EMG46227.1 - 2.4e-23 83.6 0.0 5.3e-23 82.5 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMG46227.1 - 2.3e-15 57.2 0.0 6.1e-15 55.8 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMG46227.1 - 8.4e-12 44.3 0.0 1.8e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EMG46227.1 - 0.0016 18.0 1.7 0.0022 17.6 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Peptidase_S41 PF03572.13 EMG46227.1 - 0.062 12.7 0.3 0.31 10.4 0.1 2.1 2 0 0 2 2 2 0 Peptidase family S41 Hydrolase_like2 PF13246.1 EMG46227.1 - 0.089 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit WD40 PF00400.27 EMG46228.1 - 7.9e-15 54.0 10.6 3.1e-06 26.8 1.0 6.9 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.6 EMG46228.1 - 1.1e-05 25.3 1.3 0.0092 15.7 0.0 3.3 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EMG46228.1 - 0.0034 15.7 0.1 0.13 10.4 0.0 2.6 2 0 0 2 2 2 2 Cytochrome D1 heme domain DUF3785 PF12653.2 EMG46228.1 - 0.039 13.8 0.5 0.039 13.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3785) Fungal_trans_2 PF11951.3 EMG46230.1 - 7.9e-10 37.8 0.2 1.5e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG46230.1 - 4.8e-09 35.9 12.7 1e-08 34.8 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PUF PF00806.14 EMG46231.1 - 8.2e-60 195.0 19.7 1.4e-08 33.7 0.0 8.7 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat PAT1 PF09770.4 EMG46231.1 - 0.57 8.3 43.8 0.88 7.7 30.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suc_Fer-like PF06999.7 EMG46232.1 - 5.6e-52 177.0 0.0 6.8e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Thioredoxin PF00085.15 EMG46233.1 - 9.2e-37 124.8 0.0 5.3e-19 67.8 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EMG46233.1 - 3.2e-13 49.8 0.1 2.1e-06 27.8 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EMG46233.1 - 6.5e-13 48.6 0.7 8.4e-08 32.2 0.0 3.5 2 2 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EMG46233.1 - 7.8e-10 38.6 0.0 0.00059 19.8 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 EMG46233.1 - 4.5e-06 26.3 0.1 0.0044 16.7 0.0 2.6 2 1 0 2 2 2 2 AhpC/TSA family ERp29 PF07749.7 EMG46233.1 - 5.1e-05 23.8 0.0 0.00011 22.7 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Redoxin PF08534.5 EMG46233.1 - 0.00044 19.8 0.0 0.1 12.1 0.0 2.4 2 0 0 2 2 2 1 Redoxin DIM1 PF02966.11 EMG46233.1 - 0.00049 19.6 0.0 0.1 12.0 0.0 2.3 2 0 0 2 2 2 1 Mitosis protein DIM1 HyaE PF07449.6 EMG46233.1 - 0.0019 18.1 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 EMG46233.1 - 0.0052 16.5 0.0 0.18 11.6 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin domain DUF953 PF06110.6 EMG46233.1 - 0.047 13.1 0.0 2.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) Clathrin PF00637.15 EMG46233.1 - 0.079 12.5 0.1 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 Region in Clathrin and VPS TraF PF13728.1 EMG46233.1 - 0.093 12.1 0.1 5.8 6.3 0.0 2.2 2 0 0 2 2 2 0 F plasmid transfer operon protein Hyphal_reg_CWP PF11765.3 EMG46234.1 - 2.1e-91 306.1 8.4 2.1e-91 306.1 5.8 2.4 2 1 1 3 3 3 1 Hyphally regulated cell wall protein N-terminal Flocculin_t3 PF13928.1 EMG46234.1 - 1.1e-11 44.6 26.4 1.1e-11 44.6 18.3 7.2 1 1 4 5 5 5 1 Flocculin type 3 repeat Candida_ALS PF05792.8 EMG46234.1 - 0.0011 19.0 16.8 0.0011 19.0 11.6 9.6 7 3 2 9 9 9 2 Candida agglutinin-like (ALS) SurE PF01975.12 EMG46235.1 - 1e-42 145.6 0.0 1.4e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE CPSF_A PF03178.10 EMG46236.1 - 7.2e-67 225.7 1.0 7.2e-67 225.7 0.7 2.1 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EMG46236.1 - 6.1e-47 159.9 9.4 6.1e-47 159.9 6.5 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Fork_head PF00250.13 EMG46237.1 - 9.4e-39 131.3 1.3 3.7e-38 129.4 0.9 2.1 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EMG46237.1 - 4.1e-08 33.2 0.2 1.1e-07 31.7 0.1 1.9 1 0 0 1 1 1 1 FHA domain TFIIA PF03153.8 EMG46237.1 - 0.00024 21.1 56.0 0.00024 21.1 38.8 2.3 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit OppC_N PF12911.2 EMG46238.1 - 1.3 8.3 0.0 1.3 8.3 0.0 3.8 5 0 0 5 5 5 0 N-terminal TM domain of oligopeptide transport permease C AIM24 PF01987.12 EMG46239.1 - 7.2e-06 25.6 0.0 0.00023 20.7 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial biogenesis AIM24 PIP5K PF01504.13 EMG46240.1 - 1.6e-84 283.0 0.1 2.6e-84 282.2 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 2-Hacid_dh_C PF02826.14 EMG46241.1 - 3.3e-50 169.6 0.0 4.9e-50 169.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMG46241.1 - 5.6e-12 45.2 0.0 8.7e-12 44.6 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMG46241.1 - 5.4e-06 26.3 0.0 1.3e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EMG46241.1 - 0.00078 19.8 0.0 0.0019 18.5 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 EMG46241.1 - 0.0033 16.8 0.0 0.0062 15.9 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 EMG46241.1 - 0.034 14.2 0.0 0.072 13.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase LRR_4 PF12799.2 EMG46242.1 - 2.6e-08 33.2 22.1 2.5e-05 23.7 0.0 7.9 8 2 1 9 9 9 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG46242.1 - 9.1e-08 31.7 24.5 0.002 17.8 0.0 9.1 7 2 1 9 9 9 3 Leucine rich repeat LRR_1 PF00560.28 EMG46242.1 - 4.3e-06 26.0 4.4 0.32 11.1 0.2 7.8 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_7 PF13504.1 EMG46242.1 - 0.015 15.3 10.5 3.7 8.1 0.1 8.2 9 1 1 10 10 10 0 Leucine rich repeat LRR_2 PF07723.8 EMG46242.1 - 5.1 7.7 7.4 39 4.9 0.1 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.2 EMG46244.1 - 3.6e-07 29.6 31.9 0.00026 20.5 0.8 8.7 6 3 2 8 8 8 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG46244.1 - 0.023 14.4 24.7 0.048 13.4 0.8 6.6 4 3 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.28 EMG46244.1 - 1.2 9.4 21.2 4.1 7.7 0.1 8.9 6 2 2 8 8 8 0 Leucine Rich Repeat HMG_box PF00505.14 EMG46245.1 - 6.9e-17 61.4 1.1 1.9e-16 60.0 0.8 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMG46245.1 - 5.2e-14 52.3 0.6 5.2e-14 52.3 0.4 2.3 3 0 0 3 3 3 1 HMG-box domain HMG_box_5 PF14887.1 EMG46245.1 - 0.021 14.6 0.6 0.088 12.6 0.5 2.1 2 0 0 2 2 2 0 HMG (high mobility group) box 5 DIPSY PF11763.3 EMG46245.1 - 0.024 14.4 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Cell-wall adhesin ligand-binding C-terminal DRIM PF07539.7 EMG46246.1 - 5.2e-47 158.8 0.7 2.8e-46 156.4 0.1 2.8 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT PF02985.17 EMG46246.1 - 8.2e-05 22.3 0.9 27 5.1 0.0 7.3 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.1 EMG46246.1 - 0.0089 16.2 0.1 22 5.4 0.0 5.4 4 0 0 4 4 4 1 HEAT repeats DUF155 PF02582.9 EMG46247.1 - 2.1e-59 200.3 2.3 2.7e-59 199.9 1.0 1.6 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.1 EMG46247.1 - 0.053 13.7 0.2 0.49 10.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF2439 PF10382.4 EMG46247.1 - 0.099 12.8 1.3 0.26 11.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2439) Pkinase PF00069.20 EMG46249.1 - 1.4e-35 122.6 0.0 2.1e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG46249.1 - 1.5e-12 47.2 0.0 2e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMG46249.1 - 4.5e-05 23.2 0.0 0.0044 16.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EMG46249.1 - 0.051 12.8 0.0 0.099 11.9 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL CBM_5_12_2 PF14600.1 EMG46250.1 - 0.04 13.5 0.9 0.057 13.0 0.6 1.3 1 0 0 1 1 1 0 Cellulose-binding domain Tim17 PF02466.14 EMG46252.1 - 1.4e-46 157.6 5.8 2.1e-46 157.1 4.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Abhydrolase_8 PF06259.7 EMG46252.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF2578 PF10843.3 EMG46253.1 - 5.8e-86 287.1 7.2 6.5e-86 286.9 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2578) FimP PF09766.4 EMG46253.1 - 0.092 11.8 2.5 0.13 11.3 1.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein Curto_V2 PF07325.6 EMG46253.1 - 0.33 10.6 4.9 0.51 9.9 3.4 1.4 1 0 0 1 1 1 0 Curtovirus V2 protein MRG PF05712.8 EMG46254.1 - 1.1e-43 148.4 0.2 1.6e-43 147.8 0.2 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EMG46254.1 - 4.4e-10 39.0 1.3 1.3e-09 37.6 0.9 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain RCR PF12273.3 EMG46255.1 - 7e-07 29.8 0.0 1e-06 29.3 0.0 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Shisa PF13908.1 EMG46255.1 - 0.0045 17.1 0.0 0.005 17.0 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Baculo_11_kDa PF06143.6 EMG46255.1 - 0.0086 15.4 0.1 0.014 14.7 0.1 1.3 1 0 0 1 1 1 1 Baculovirus 11 kDa family FAM176 PF14851.1 EMG46255.1 - 0.041 13.5 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 FAM176 family ODV-E18 PF10717.4 EMG46255.1 - 0.083 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 SurA_N_2 PF13623.1 EMG46255.1 - 0.14 12.1 0.1 0.19 11.7 0.0 1.1 1 0 0 1 1 1 0 SurA N-terminal domain MtrG PF04210.8 EMG46255.1 - 0.32 10.6 4.2 0.58 9.8 2.9 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G Myc_target_1 PF15179.1 EMG46255.1 - 0.48 9.9 3.9 0.097 12.2 0.4 1.6 1 1 1 2 2 2 0 Myc target protein 1 RCR PF12273.3 EMG46256.1 - 7.5e-09 36.2 7.4 8.9e-08 32.7 5.1 2.0 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red RAMP4 PF06624.7 EMG46256.1 - 0.06 12.8 0.9 1.1 8.8 0.1 2.2 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 SIT PF15330.1 EMG46256.1 - 0.097 12.8 0.2 0.19 11.9 0.1 1.6 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF1049 PF06305.6 EMG46256.1 - 0.13 11.7 0.3 0.22 11.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Glycophorin_A PF01102.13 EMG46256.1 - 0.85 9.4 4.8 3.4 7.4 0.2 2.2 1 1 1 2 2 2 0 Glycophorin A RCR PF12273.3 EMG46257.1 - 7.8e-08 32.9 10.8 2e-07 31.6 7.5 1.6 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red IncA PF04156.9 EMG46257.1 - 0.0046 16.5 0.0 0.0052 16.4 0.0 1.1 1 0 0 1 1 1 1 IncA protein Shisa PF13908.1 EMG46257.1 - 0.078 13.1 0.0 0.089 12.9 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4097 PF13349.1 EMG46257.1 - 0.09 12.3 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) RCR PF12273.3 EMG46258.1 - 1.6e-09 38.4 0.1 2.5e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red InaF-motif PF15018.1 EMG46258.1 - 0.036 13.5 0.6 0.059 12.8 0.4 1.2 1 0 0 1 1 1 0 TRP-interacting helix DUF3357 PF11837.3 EMG46258.1 - 0.051 13.4 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF2207 PF09972.4 EMG46258.1 - 0.097 11.2 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RRN3 PF05327.6 EMG46259.1 - 0.58 8.2 6.6 0.97 7.4 4.5 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF912 PF06024.7 EMG46259.1 - 0.61 10.1 0.0 0.61 10.1 0.0 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Rad54_N PF08658.5 EMG46259.1 - 0.82 9.4 6.2 0.1 12.3 1.1 1.8 2 0 0 2 2 2 0 Rad54 N terminal P5-ATPase PF12409.3 EMG46259.1 - 3.5 7.5 5.3 14 5.5 3.6 2.3 1 1 0 1 1 1 0 P5-type ATPase cation transporter WD40 PF00400.27 EMG46260.1 - 2.2e-08 33.6 0.4 0.025 14.4 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat eIF2A PF08662.6 EMG46260.1 - 0.011 15.4 0.0 0.011 15.4 0.0 2.9 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Methyltransf_8 PF05148.10 EMG46261.1 - 1.2e-64 217.9 2.0 1.7e-62 210.8 0.3 2.8 1 1 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EMG46261.1 - 9.2e-07 29.2 0.0 3.2e-06 27.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMG46261.1 - 0.00017 21.1 0.1 0.00031 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CPSF100_C PF13299.1 EMG46261.1 - 0.0079 16.4 6.0 0.019 15.1 4.2 1.6 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Methyltransf_32 PF13679.1 EMG46261.1 - 0.021 14.5 0.0 0.058 13.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Trypan_PARP PF05887.6 EMG46261.1 - 0.081 12.7 6.9 0.15 11.9 4.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Methyltransf_25 PF13649.1 EMG46261.1 - 0.15 12.4 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF2413 PF10310.4 EMG46261.1 - 2.1 7.0 16.7 4.5 5.9 11.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Presenilin PF01080.12 EMG46261.1 - 3.4 6.4 4.1 5.2 5.7 2.9 1.2 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.5 EMG46261.1 - 6.5 5.0 7.4 9.2 4.5 5.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Stn1 PF10451.4 EMG46262.1 - 4.2e-16 58.5 0.4 7.6e-16 57.7 0.3 1.4 1 0 0 1 1 1 1 Telomere regulation protein Stn1 Transthyretin PF00576.16 EMG46263.1 - 1.2e-27 96.0 0.2 3.6e-25 88.0 0.1 2.1 1 1 0 1 1 1 1 HIUase/Transthyretin family DUF2606 PF10794.4 EMG46263.1 - 0.0064 15.9 0.1 0.0091 15.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2606) MG1 PF11974.3 EMG46263.1 - 0.03 14.8 0.0 0.041 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin MG1 domain Pox_Ag35 PF03286.9 EMG46265.1 - 0.017 14.6 3.5 0.024 14.1 2.4 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Actino_peptide PF14408.1 EMG46265.1 - 7.1 6.6 15.2 14 5.7 10.6 1.4 1 0 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes HhH-GPD PF00730.20 EMG46266.1 - 1.6e-14 54.0 0.0 3.2e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DNA_topoisoIV PF00521.15 EMG46266.1 - 0.029 13.2 0.1 0.19 10.5 0.1 2.3 1 1 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Abhydrolase_6 PF12697.2 EMG46267.1 - 4.6e-21 75.7 0.0 5.9e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMG46267.1 - 7.9e-08 32.1 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMG46267.1 - 2.7e-07 30.4 0.0 1.5e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EMG46267.1 - 1.4e-05 24.6 0.0 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 EMG46267.1 - 0.0019 17.4 0.0 0.0057 15.8 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family PGAP1 PF07819.8 EMG46267.1 - 0.004 16.7 0.1 0.008 15.7 0.1 1.6 1 1 0 1 1 1 1 PGAP1-like protein FSH1 PF03959.8 EMG46267.1 - 0.017 14.5 0.2 0.093 12.1 0.0 2.1 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Lipase_3 PF01764.20 EMG46267.1 - 0.019 14.6 0.0 0.06 12.9 0.0 1.7 1 1 0 1 1 1 0 Lipase (class 3) BRCT PF00533.21 EMG46268.1 - 1.8e-30 104.8 4.3 3.3e-07 30.3 0.0 5.2 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EMG46268.1 - 3.2e-26 90.9 0.2 6.2e-05 22.7 0.0 5.4 5 0 0 5 5 5 5 twin BRCT domain Peptidase_M26_C PF07580.9 EMG46268.1 - 0.62 8.2 7.0 0.91 7.7 4.9 1.1 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region Sporozoite_P67 PF05642.6 EMG46268.1 - 1.1 7.0 7.2 1.9 6.2 5.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.1 EMG46268.1 - 4.3 7.0 9.9 1.3 8.7 2.8 2.3 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.1 EMG46268.1 - 9.1 6.6 16.2 14 6.0 6.2 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal p25-alpha PF05517.7 EMG46269.1 - 0.012 15.9 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 p25-alpha DUF4336 PF14234.1 EMG46269.1 - 0.054 12.6 0.0 5 6.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4336) V-ATPase_C PF03223.10 EMG46270.1 - 6.5e-112 374.1 9.3 7.4e-112 373.9 6.4 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Baculo_PEP_C PF04513.7 EMG46270.1 - 2.8 7.7 8.6 3.4 7.5 4.1 2.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SURF6 PF04935.7 EMG46271.1 - 3.5e-48 163.7 50.8 3.5e-48 163.7 35.2 2.8 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.1 EMG46271.1 - 5.1e-20 71.3 4.3 5.1e-20 71.3 2.9 6.9 4 1 0 4 4 4 1 60S ribosome biogenesis protein Rrp14 DUF99 PF01949.11 EMG46271.1 - 0.23 10.5 2.3 0.49 9.4 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF99 PIP49_N PF14875.1 EMG46271.1 - 1.9 8.1 7.5 0.11 12.1 0.6 2.3 2 1 1 3 3 3 0 N-term cysteine-rich ER, FAM69 TB2_DP1_HVA22 PF03134.14 EMG46272.1 - 2.5e-27 94.4 4.2 3.4e-27 94.0 2.9 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF221 PF02714.10 EMG46274.1 - 1.2e-102 343.1 28.6 1.4e-102 342.9 14.9 3.0 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EMG46274.1 - 3.4e-39 133.9 2.2 3.4e-39 133.9 1.5 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EMG46274.1 - 2.3e-29 101.1 0.2 1e-28 99.0 0.1 2.1 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EMG46274.1 - 4.6e-19 68.7 7.9 8.4e-19 67.8 5.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) TMEM154 PF15102.1 EMG46274.1 - 1.6 8.3 5.6 0.67 9.6 0.0 2.4 2 0 0 2 2 2 0 TMEM154 protein family HECT PF00632.20 EMG46275.1 - 1.5e-89 300.2 0.0 2.2e-89 299.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EMG46275.1 - 5.9e-33 112.3 20.7 6.5e-11 41.8 1.9 3.6 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EMG46275.1 - 1.9e-16 59.6 0.5 4.4e-16 58.5 0.3 1.7 1 0 0 1 1 1 1 C2 domain ArfGap PF01412.13 EMG46276.1 - 4.7e-41 139.2 3.8 4.7e-41 139.2 2.6 2.4 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Phostensin_N PF13916.1 EMG46276.1 - 0.079 12.9 1.2 0.2 11.6 0.8 1.6 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Nitr_red_assoc PF09655.5 EMG46276.1 - 0.14 12.5 4.3 0.47 10.7 0.2 2.4 2 0 0 2 2 2 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) PCI PF01399.22 EMG46277.1 - 5.2e-07 29.9 1.0 5.2e-07 29.9 0.7 3.2 2 1 0 2 2 2 1 PCI domain FeoC PF09012.5 EMG46277.1 - 0.0064 16.1 0.2 0.018 14.7 0.1 1.9 2 0 0 2 2 2 1 FeoC like transcriptional regulator PRD PF00874.15 EMG46277.1 - 0.023 14.8 3.7 0.074 13.1 0.1 3.0 1 1 2 3 3 3 0 PRD domain CAMSAP_CH PF11971.3 EMG46277.1 - 0.032 13.8 0.8 9.9 5.8 0.0 2.9 2 0 0 2 2 2 0 CAMSAP CH domain Cyt-b5 PF00173.23 EMG46278.1 - 1.5e-21 75.9 0.1 2.6e-21 75.2 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Nop14 PF04147.7 EMG46278.1 - 1.1e-05 23.5 3.6 1.1e-05 23.5 2.5 1.2 1 0 0 1 1 1 1 Nop14-like family DUF2951 PF11166.3 EMG46278.1 - 0.011 15.5 3.9 0.011 15.5 2.7 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) Pox_RNA_Pol_19 PF05320.7 EMG46278.1 - 0.5 10.1 10.6 0.024 14.3 3.3 1.7 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit CDC45 PF02724.9 EMG46278.1 - 0.58 8.1 16.8 0.87 7.5 11.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Spt5_N PF11942.3 EMG46278.1 - 6.7 7.4 20.2 9.3 6.9 13.0 2.0 1 1 1 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Nop53 PF07767.6 EMG46278.1 - 8.4 5.2 20.1 0.24 10.3 9.6 1.5 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) YjbE PF11106.3 EMG46280.1 - 1.8 8.5 12.5 0.78 9.7 0.8 2.3 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE Dus PF01207.12 EMG46283.1 - 4e-70 236.0 0.0 4.8e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 EMG46283.1 - 5.7e-05 22.2 0.4 0.00073 18.5 0.3 2.1 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase S-methyl_trans PF02574.11 EMG46283.1 - 0.092 12.0 0.0 2.8 7.1 0.0 2.3 1 1 0 2 2 2 0 Homocysteine S-methyltransferase RMMBL PF07521.7 EMG46283.1 - 0.11 12.2 0.0 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 RNA-metabolising metallo-beta-lactamase Endonuclease_NS PF01223.18 EMG46284.1 - 4.5e-56 189.7 0.0 5.9e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Pacifastin_I PF05375.8 EMG46285.1 - 0.019 14.4 5.9 0.037 13.5 4.1 1.5 1 0 0 1 1 1 0 Pacifastin inhibitor (LCMII) DUF4362 PF14275.1 EMG46285.1 - 0.36 10.8 3.7 2.1 8.4 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4362) HTH_Tnp_Tc5 PF03221.11 EMG46286.1 - 2.7e-13 49.5 1.8 4e-13 48.9 0.1 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Cofilin_ADF PF00241.15 EMG46287.1 - 4.1e-44 149.5 0.4 4.6e-44 149.3 0.3 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF4299 PF14132.1 EMG46287.1 - 0.097 11.7 0.5 0.13 11.4 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4299) GCV_T PF01571.16 EMG46287.1 - 0.1 11.9 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain DUF2318 PF10080.4 EMG46287.1 - 0.11 12.3 0.1 0.61 9.8 0.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) DnaJ PF00226.26 EMG46288.1 - 1.6e-25 88.5 3.2 2.8e-25 87.8 2.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EMG46288.1 - 3.1e-13 49.5 11.5 6.6e-13 48.5 7.9 1.6 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 EMG46288.1 - 1.5e-08 34.4 4.1 5.9e-07 29.3 0.0 3.2 3 0 0 3 3 3 1 DnaJ C terminal domain Cytochrom_c3_2 PF14537.1 EMG46288.1 - 0.0027 18.0 2.0 0.0027 18.0 1.4 1.9 1 1 1 2 2 2 2 Cytochrome c3 IceA2 PF05862.6 EMG46288.1 - 0.02 14.5 0.1 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 Helicobacter pylori IceA2 protein SPOUT_MTase_2 PF14419.1 EMG46288.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP Cytochrome_CBB3 PF13442.1 EMG46288.1 - 0.18 11.9 2.7 1.4 9.1 0.3 2.8 2 1 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III VARLMGL PF14383.1 EMG46288.1 - 0.33 10.1 1.6 1.5 8.0 0.0 2.3 2 0 0 2 2 2 0 DUF761-associated sequence motif zf-CHY PF05495.7 EMG46288.1 - 0.45 10.7 6.4 0.82 9.8 0.7 2.5 1 1 0 2 2 2 0 CHY zinc finger Cytochrome_C554 PF13435.1 EMG46288.1 - 1.8 8.6 6.2 13 5.8 4.3 2.2 1 1 0 1 1 1 0 Cytochrome c554 and c-prime Cytochrome_C7 PF14522.1 EMG46288.1 - 3.2 7.4 7.0 0.37 10.4 0.7 2.3 1 1 1 2 2 2 0 Cytochrome c7 HypA PF01155.14 EMG46288.1 - 5.7 6.6 6.8 5.4 6.7 0.2 2.7 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF98 PF01947.11 EMG46289.1 - 0.075 12.7 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF98) Env-gp36 PF09590.5 EMG46289.1 - 0.14 10.3 1.3 0.18 9.9 0.9 1.1 1 0 0 1 1 1 0 Lentivirus surface glycoprotein RNA_polI_A14 PF08203.6 EMG46291.1 - 2e-21 76.0 0.1 2e-21 76.0 0.0 2.0 2 0 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 CobT PF06213.7 EMG46291.1 - 0.0045 16.1 10.0 0.0047 16.0 6.9 1.1 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 EMG46291.1 - 0.015 13.3 12.6 0.013 13.5 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 EMG46291.1 - 0.038 13.8 14.8 0.041 13.7 10.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med19 PF10278.4 EMG46291.1 - 0.061 12.9 14.2 0.089 12.4 9.8 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF1510 PF07423.6 EMG46291.1 - 0.23 10.7 19.3 0.26 10.6 13.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Herpes_DNAp_acc PF04929.7 EMG46291.1 - 0.52 9.2 11.4 0.54 9.1 7.9 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Paf1 PF03985.8 EMG46291.1 - 1.8 7.2 18.7 2 7.0 13.0 1.1 1 0 0 1 1 1 0 Paf1 Hid1 PF12722.2 EMG46291.1 - 2 6.0 8.3 1.6 6.2 5.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RP-C_C PF11800.3 EMG46291.1 - 2 8.0 6.8 2.2 7.9 4.7 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Zip PF02535.17 EMG46291.1 - 2.8 6.8 4.4 2.9 6.7 3.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter YqfQ PF14181.1 EMG46291.1 - 4.2 7.3 16.2 7.9 6.4 11.2 1.4 1 0 0 1 1 1 0 YqfQ-like protein SMC_N PF02463.14 EMG46292.1 - 1.7e-64 217.1 58.3 7.2e-63 211.7 40.4 3.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EMG46292.1 - 1.3e-25 89.6 0.0 7.9e-25 87.1 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EMG46292.1 - 6.7e-07 29.5 51.3 2.1e-05 24.6 5.6 4.7 3 2 1 4 4 4 2 AAA domain AAA_29 PF13555.1 EMG46292.1 - 0.00011 21.5 0.0 0.00023 20.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain APG6 PF04111.7 EMG46292.1 - 0.0041 16.2 22.1 0.0041 16.2 15.3 6.3 2 2 4 6 6 6 3 Autophagy protein Apg6 HrpB7 PF09486.5 EMG46292.1 - 0.0055 16.6 0.8 0.0055 16.6 0.6 7.2 4 2 2 7 7 7 1 Bacterial type III secretion protein (HrpB7) Reo_sigmaC PF04582.7 EMG46292.1 - 1.6 7.8 51.2 0.023 13.8 1.2 6.5 3 2 5 8 8 8 0 Reovirus sigma C capsid protein Mito_carr PF00153.22 EMG46293.1 - 1.6e-68 226.4 4.9 6.1e-24 83.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial_8 PF08103.6 EMG46293.1 - 0.084 12.8 1.2 1 9.3 0.0 2.6 2 0 0 2 2 2 0 Uperin family Ribosomal_S6 PF01250.12 EMG46294.1 - 9.6e-07 28.5 0.0 1.2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 Hydrolase_like2 PF13246.1 EMG46295.1 - 3.8e-14 52.4 0.1 1.9e-13 50.1 0.0 2.4 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 EMG46295.1 - 7.4e-13 48.0 0.0 7.4e-13 48.0 0.0 2.2 3 0 0 3 3 3 1 E1-E2 ATPase HAD PF12710.2 EMG46295.1 - 2.6e-12 47.3 0.0 6.3e-12 46.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMG46295.1 - 5.3e-11 43.3 1.6 1.4e-07 32.1 0.7 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMG46295.1 - 0.0012 18.4 3.2 0.0023 17.5 0.1 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Neurochondrin PF05536.6 EMG46295.1 - 0.11 10.8 0.3 14 3.7 0.0 2.7 3 0 0 3 3 3 0 Neurochondrin APS_kinase PF01583.15 EMG46296.1 - 8.7e-72 239.8 0.0 1.1e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EMG46296.1 - 9e-07 28.8 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMG46296.1 - 0.00019 22.2 0.0 0.00042 21.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMG46296.1 - 0.0013 17.8 0.0 0.019 14.0 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin KTI12 PF08433.5 EMG46296.1 - 0.002 17.3 0.0 0.0023 17.2 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 EMG46296.1 - 0.0039 16.6 0.0 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EMG46296.1 - 0.016 15.4 0.0 0.067 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Snf7 PF03357.16 EMG46297.1 - 1.2e-30 106.1 23.6 2.7e-30 104.9 14.6 2.1 2 0 0 2 2 2 1 Snf7 DAO PF01266.19 EMG46297.1 - 4.9e-17 61.8 0.0 1.4e-16 60.3 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Ist1 PF03398.9 EMG46297.1 - 0.00031 20.1 4.7 0.0005 19.5 3.3 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway NAD_binding_8 PF13450.1 EMG46297.1 - 0.016 15.2 0.4 0.054 13.5 0.3 2.0 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Uds1 PF15456.1 EMG46297.1 - 0.039 13.9 0.4 0.039 13.9 0.3 2.4 2 0 0 2 2 2 0 Up-regulated During Septation Pyr_redox PF00070.22 EMG46297.1 - 0.076 13.4 5.6 0.76 10.2 0.7 3.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMG46297.1 - 0.076 12.8 1.1 1.1 9.1 0.2 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF342 PF03961.8 EMG46297.1 - 1.3 7.3 8.7 2 6.7 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Cu-oxidase_3 PF07732.10 EMG46298.1 - 7.5e-44 148.2 1.7 3.2e-41 139.7 0.2 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMG46298.1 - 5.7e-42 142.4 8.8 7.3e-40 135.6 1.0 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EMG46298.1 - 3.6e-29 101.7 4.6 1.1e-28 100.1 0.3 3.0 3 0 0 3 3 3 1 Multicopper oxidase DUF4580 PF15162.1 EMG46298.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4580) SKN1 PF03935.10 EMG46299.1 - 2.6e-172 573.4 6.0 3.2e-172 573.2 4.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Caveolin PF01146.12 EMG46299.1 - 0.33 10.5 2.5 0.72 9.4 1.7 1.5 1 0 0 1 1 1 0 Caveolin CRAL_TRIO PF00650.15 EMG46300.1 - 1.3e-36 125.5 0.0 2e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMG46300.1 - 8e-07 29.0 0.5 3.6e-05 23.7 0.1 2.5 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EMG46300.1 - 0.00015 21.6 0.0 0.00037 20.4 0.0 1.6 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain CSTF_C PF14304.1 EMG46300.1 - 0.097 11.9 0.1 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal AIF-MLS PF14962.1 EMG46301.1 - 0.032 13.8 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence UQ_con PF00179.21 EMG46302.1 - 1.1e-46 157.7 0.0 1.3e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMG46302.1 - 4.4e-05 23.2 0.0 5.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EMG46302.1 - 0.045 13.4 0.1 0.095 12.3 0.0 1.6 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 EMG46302.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 RWD domain Med17 PF10156.4 EMG46304.1 - 0.092 11.0 0.3 0.16 10.2 0.1 1.4 1 1 0 1 1 1 0 Subunit 17 of Mediator complex UPF1_Zn_bind PF09416.5 EMG46307.1 - 6.6e-70 233.5 8.0 6.6e-70 233.5 5.6 2.8 3 0 0 3 3 3 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 EMG46307.1 - 8.6e-59 198.2 0.1 2.4e-57 193.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EMG46307.1 - 5.1e-52 176.8 1.8 5.1e-52 176.8 1.2 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EMG46307.1 - 3.9e-14 52.6 0.1 3e-13 49.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMG46307.1 - 2.3e-13 49.6 0.2 6.1e-13 48.3 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 EMG46307.1 - 4.3e-06 26.4 0.0 0.23 10.9 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EMG46307.1 - 2.4e-05 23.4 0.0 0.00016 20.8 0.0 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EMG46307.1 - 4.1e-05 23.4 2.2 5.1e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 EMG46307.1 - 0.0016 18.1 0.0 0.0046 16.6 0.0 1.9 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 EMG46307.1 - 0.0084 15.0 1.0 3.4 6.5 0.0 2.7 3 0 0 3 3 3 2 PIF1-like helicase Ribosomal_S13_N PF08069.7 EMG46307.1 - 0.011 15.5 0.1 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain PhoH PF02562.11 EMG46307.1 - 0.038 13.2 0.0 0.088 12.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein DEAD PF00270.24 EMG46307.1 - 0.04 13.4 0.2 0.15 11.5 0.1 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.1 EMG46307.1 - 0.06 13.4 0.1 0.64 10.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EMG46307.1 - 0.082 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA PF00004.24 EMG46307.1 - 0.13 12.4 0.0 0.46 10.6 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MRP-L46 PF11788.3 EMG46308.1 - 1e-35 122.7 1.3 1.8e-35 121.9 0.9 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 DUF106 PF01956.11 EMG46309.1 - 0.027 14.0 0.1 0.039 13.4 0.1 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 FYRC PF05965.9 EMG46309.1 - 0.07 12.9 0.2 0.27 11.0 0.0 2.1 2 0 0 2 2 2 0 F/Y rich C-terminus zf-CCHC PF00098.18 EMG46310.1 - 8.9e-49 161.2 58.8 1.7e-08 33.9 1.4 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EMG46310.1 - 3.7e-11 42.5 48.3 0.012 15.2 0.3 7.0 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 EMG46310.1 - 2.6e-08 33.4 46.5 0.056 13.1 0.6 7.0 1 1 6 7 7 7 7 Zinc knuckle zf-CCHC_6 PF15288.1 EMG46310.1 - 0.015 14.9 2.2 0.015 14.9 1.5 6.8 5 1 2 7 7 7 0 Zinc knuckle Exo_endo_phos PF03372.18 EMG46311.1 - 8.5e-10 38.9 0.0 1.2e-09 38.5 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3449 PF11931.3 EMG46312.1 - 7e-10 38.7 0.8 7e-10 38.7 0.6 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) zf-C2H2_jaz PF12171.3 EMG46312.1 - 0.00025 21.0 3.4 0.00025 21.0 2.4 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 EMG46312.1 - 0.0015 18.0 0.8 0.0034 16.8 0.6 1.6 1 0 0 1 1 1 1 U1 zinc finger zf-met PF12874.2 EMG46312.1 - 0.0042 17.2 1.2 0.0042 17.2 0.8 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 EMG46312.1 - 0.025 14.2 0.5 0.49 10.1 0.2 2.6 2 0 0 2 2 2 0 DBF zinc finger zf-C2H2_2 PF12756.2 EMG46312.1 - 6 7.0 9.4 0.9 9.6 1.9 2.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) XPG_N PF00752.12 EMG46314.1 - 1.5e-25 89.3 0.0 3.3e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EMG46314.1 - 1e-24 86.4 0.0 3.8e-24 84.5 0.0 2.1 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EMG46314.1 - 9.7e-05 22.5 0.0 0.00046 20.3 0.0 2.2 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.2 EMG46314.1 - 0.0081 16.0 0.1 0.037 13.9 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif XPG_I_2 PF12813.2 EMG46314.1 - 0.0097 15.4 0.0 0.044 13.2 0.0 2.0 1 1 0 1 1 1 1 XPG domain containing Bac_surface_Ag PF01103.18 EMG46315.1 - 2.7e-11 43.5 23.2 4.3e-11 42.8 16.0 1.4 1 0 0 1 1 1 1 Surface antigen GHMP_kinases_N PF00288.21 EMG46316.1 - 2.1e-13 50.1 0.0 3.9e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EMG46316.1 - 0.0046 17.1 0.0 0.0089 16.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal p450 PF00067.17 EMG46317.1 - 9.1e-90 301.3 0.0 1.1e-89 301.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ASL_C2 PF14698.1 EMG46317.1 - 0.095 12.7 0.0 2.4 8.2 0.0 2.5 2 0 0 2 2 2 0 Argininosuccinate lyase C-terminal HLH PF00010.21 EMG46318.1 - 1.9e-15 56.2 0.0 6.8e-15 54.5 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain AIF_C PF14721.1 EMG46318.1 - 5.1 7.3 22.7 10 6.3 0.2 4.6 4 0 0 4 4 4 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RRM_1 PF00076.17 EMG46319.1 - 1.4e-06 27.8 0.0 2.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG46319.1 - 0.00019 21.3 0.0 0.00045 20.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG46319.1 - 0.0031 17.3 0.0 0.0058 16.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EMG46319.1 - 0.13 12.5 0.2 1.1 9.5 0.1 2.5 1 1 0 1 1 1 0 RNA polymerase II-binding domain. AMPKBI PF04739.10 EMG46320.1 - 0.022 14.5 0.4 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interation domain DUF1027 PF06265.6 EMG46320.1 - 0.029 14.2 0.2 0.14 12.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1027) MAT1 PF06391.8 EMG46321.1 - 9.2e-40 136.3 30.7 1e-39 136.1 21.3 1.0 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 EMG46321.1 - 0.0089 15.6 7.8 0.022 14.3 5.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMG46321.1 - 0.01 15.8 6.0 0.026 14.5 4.2 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMG46321.1 - 0.027 14.1 5.6 0.05 13.2 3.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMG46321.1 - 0.061 13.1 6.0 0.12 12.2 4.1 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 EMG46321.1 - 0.25 11.1 7.9 0.69 9.6 5.5 1.8 1 1 0 1 1 1 0 zinc-RING finger domain DUF3635 PF12330.3 EMG46321.1 - 0.37 10.8 11.7 0.091 12.8 1.6 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3635) IBR PF01485.16 EMG46321.1 - 1.8 8.4 6.5 12 5.8 3.8 2.6 1 1 0 1 1 1 0 IBR domain FYDLN_acid PF09538.5 EMG46321.1 - 5.9 7.5 14.0 8.5e+02 0.5 9.6 2.7 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-RING_4 PF14570.1 EMG46321.1 - 9 5.9 9.4 41 3.8 6.5 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain SAM_decarbox PF01536.11 EMG46322.1 - 2.5e-96 322.2 3.2 3.1e-96 321.9 2.2 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase RasGAP PF00616.14 EMG46323.1 - 8e-61 205.1 5.6 2.1e-60 203.8 3.9 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EMG46323.1 - 0.0006 19.6 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain CENP-B_dimeris PF09026.5 EMG46323.1 - 0.46 10.7 13.5 0.064 13.5 5.9 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain EF-1_beta_acid PF10587.4 EMG46323.1 - 2.6 8.2 10.8 6.8 6.9 7.5 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Cwf_Cwc_15 PF04889.7 EMG46323.1 - 6.2 6.4 23.9 0.054 13.1 6.1 2.9 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Nucleoplasmin PF03066.10 EMG46323.1 - 8.6 5.8 11.6 21 4.6 8.0 1.6 1 0 0 1 1 1 0 Nucleoplasmin RTC4 PF14474.1 EMG46324.1 - 4.5e-36 123.5 0.1 8.5e-36 122.6 0.1 1.5 1 0 0 1 1 1 1 RTC4-like domain Pterin_bind PF00809.17 EMG46325.1 - 3.1e-57 193.3 0.8 1.2e-44 152.1 0.0 3.7 2 1 1 3 3 3 2 Pterin binding enzyme HPPK PF01288.15 EMG46325.1 - 1.2e-36 125.2 0.0 2.6e-36 124.1 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 EMG46325.1 - 7.4e-36 122.7 3.9 2.3e-17 63.2 0.1 2.8 3 0 0 3 3 3 2 Dihydroneopterin aldolase RabGAP-TBC PF00566.13 EMG46326.1 - 3.5e-41 141.0 1.1 6.5e-41 140.1 0.1 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain ISG65-75 PF11727.3 EMG46326.1 - 0.046 12.7 0.6 0.074 12.1 0.4 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein PalH PF08733.5 EMG46327.1 - 3.3e-108 361.6 20.8 4.9e-108 361.0 14.4 1.2 1 0 0 1 1 1 1 PalH/RIM21 CDC45 PF02724.9 EMG46327.1 - 0.0037 15.3 2.9 0.0063 14.6 1.8 1.4 1 1 0 1 1 1 1 CDC45-like protein PseudoU_synth_2 PF00849.17 EMG46328.1 - 6.3e-32 110.6 0.1 1.1e-31 109.9 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase dCMP_cyt_deam_1 PF00383.17 EMG46328.1 - 1e-18 66.8 0.1 2.1e-18 65.8 0.1 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region S4 PF01479.20 EMG46328.1 - 0.16 11.4 1.3 0.25 10.8 0.0 2.0 2 0 0 2 2 2 0 S4 domain NARP1 PF12569.3 EMG46329.1 - 2.5e-131 439.0 23.6 1.4e-96 324.3 2.2 3.9 2 2 2 4 4 4 3 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 EMG46329.1 - 3.8e-17 62.4 11.3 6.3e-05 23.5 0.1 8.8 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 EMG46329.1 - 1e-13 51.3 15.8 0.00032 20.9 0.3 7.8 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMG46329.1 - 3.3e-13 48.4 26.8 0.017 14.9 0.1 10.2 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 EMG46329.1 - 1.2e-11 44.1 6.7 0.19 12.4 0.0 8.9 7 1 4 11 11 9 2 Tetratricopeptide repeat Apc3 PF12895.2 EMG46329.1 - 2.8e-10 40.1 25.5 0.012 15.7 0.5 7.2 4 3 3 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EMG46329.1 - 7.4e-10 38.3 25.1 0.0011 18.5 1.0 7.6 4 2 3 8 8 8 4 TPR repeat TPR_17 PF13431.1 EMG46329.1 - 1.5e-07 31.0 17.7 3.1 8.2 0.2 9.7 8 2 1 9 9 9 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMG46329.1 - 1e-06 28.5 19.5 0.063 13.2 0.4 7.1 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMG46329.1 - 0.00012 21.5 29.4 0.39 10.4 0.0 9.6 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_21 PF09976.4 EMG46329.1 - 0.00064 19.6 3.2 0.029 14.3 0.3 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMG46329.1 - 0.0011 18.6 10.9 3.6 7.6 0.0 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat DUF357 PF04010.8 EMG46329.1 - 0.086 12.5 7.8 0.8 9.4 0.1 5.0 4 1 1 5 5 5 0 Protein of unknown function (DUF357) Fis1_TPR_C PF14853.1 EMG46329.1 - 0.21 11.4 12.8 2.1 8.2 0.2 5.1 5 1 1 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 EMG46329.1 - 0.68 9.9 5.5 11 6.1 0.1 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat Sel1 PF08238.7 EMG46329.1 - 1.7 9.3 6.3 1.1 9.9 0.2 3.9 5 0 0 5 5 4 0 Sel1 repeat SPO22 PF08631.5 EMG46329.1 - 1.9 7.4 14.9 0.41 9.6 0.7 4.6 5 1 0 5 5 5 0 Meiosis protein SPO22/ZIP4 like TPR_6 PF13174.1 EMG46329.1 - 10 6.8 17.5 8.5 7.0 0.1 7.6 9 0 0 9 9 8 0 Tetratricopeptide repeat Got1 PF04178.7 EMG46330.1 - 1.9e-30 105.4 20.7 2.6e-30 104.9 14.4 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Sugar_tr PF00083.19 EMG46331.1 - 3.7e-26 91.7 26.9 4.7e-20 71.5 8.1 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMG46331.1 - 1.3e-15 57.0 41.0 4.4e-07 28.9 11.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TCR_zetazeta PF11628.3 EMG46331.1 - 0.1 12.0 0.1 0.63 9.5 0.0 2.3 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain Transgly_assoc PF04226.8 EMG46331.1 - 0.19 11.8 0.0 0.19 11.8 0.0 4.4 5 0 0 5 5 5 0 Transglycosylase associated protein MULE PF10551.4 EMG46333.1 - 0.00026 21.1 0.0 0.00073 19.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Striatin PF08232.7 EMG46333.1 - 0.011 16.0 3.6 0.043 14.1 2.5 2.0 1 0 0 1 1 1 0 Striatin family DUF904 PF06005.7 EMG46333.1 - 3.1 8.1 6.7 3.8 7.8 1.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Sugar_tr PF00083.19 EMG46334.1 - 2.2e-22 79.2 39.5 2.1e-15 56.2 11.5 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMG46334.1 - 4.3e-16 58.5 47.7 6.3e-08 31.7 12.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Transgly_assoc PF04226.8 EMG46334.1 - 0.17 12.0 0.0 0.17 12.0 0.0 5.0 5 0 0 5 5 5 0 Transglycosylase associated protein COPIIcoated_ERV PF07970.7 EMG46335.1 - 3.6e-74 249.1 0.2 4.4e-74 248.8 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EMG46335.1 - 4.7e-32 109.8 3.1 1.3e-31 108.4 0.9 2.3 3 0 0 3 3 3 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sugar_tr PF00083.19 EMG46336.1 - 1.7e-14 53.2 10.3 2e-14 53.0 7.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG46336.1 - 1.4e-10 40.4 11.9 1.8e-10 40.0 8.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.3 EMG46336.1 - 0.00014 20.5 7.3 0.00019 20.0 5.1 1.2 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_2 PF13347.1 EMG46336.1 - 0.018 13.4 6.8 0.025 12.9 4.6 1.3 1 1 0 1 1 1 0 MFS/sugar transport protein WD40 PF00400.27 EMG46337.1 - 1e-16 60.0 12.4 1.8e-06 27.5 0.2 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat SdiA-regulated PF06977.6 EMG46337.1 - 0.0012 17.8 0.0 0.0097 14.8 0.0 2.1 2 0 0 2 2 2 1 SdiA-regulated Nucleoporin_N PF08801.6 EMG46337.1 - 0.056 12.1 5.7 0.18 10.5 0.1 2.9 1 1 2 3 3 3 0 Nup133 N terminal like Peptidase_S24 PF00717.18 EMG46338.1 - 1.4e-09 37.4 0.3 2.6e-09 36.5 0.2 1.5 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EMG46338.1 - 2e-06 27.3 0.0 0.0026 17.3 0.0 2.5 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 CBFD_NFYB_HMF PF00808.18 EMG46339.1 - 5.1e-19 68.0 0.7 5.1e-19 68.0 0.5 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMG46339.1 - 4.4e-12 45.9 0.0 1.2e-11 44.5 0.1 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 SET PF00856.23 EMG46339.1 - 6.7e-08 33.0 17.0 1.3e-07 32.0 0.1 4.4 3 2 0 3 3 3 2 SET domain HTH_21 PF13276.1 EMG46339.1 - 0.0049 16.8 0.1 0.069 13.1 0.0 2.4 2 0 0 2 2 2 1 HTH-like domain Ecl1 PF12855.2 EMG46339.1 - 0.0095 15.2 2.7 0.032 13.5 1.9 1.9 1 0 0 1 1 1 1 Life-span regulatory factor CENP-X PF09415.5 EMG46339.1 - 0.023 14.4 0.1 0.071 12.9 0.1 1.9 1 0 0 1 1 1 0 CENP-S associating Centromere protein X SAF PF08666.7 EMG46339.1 - 0.043 14.2 0.0 23 5.4 0.0 3.0 4 0 0 4 4 4 0 SAF domain PBP PF01161.15 EMG46340.1 - 1.9e-32 112.0 0.3 2.3e-32 111.8 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DIM1 PF02966.11 EMG46341.1 - 8.1e-65 216.3 0.2 9.1e-65 216.1 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 EMG46342.1 - 1.8e-18 66.0 0.2 2.2e-18 65.8 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EMG46342.1 - 2.2e-05 24.6 0.1 7.6e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EMG46342.1 - 0.00054 20.0 0.1 0.016 15.2 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_5 PF13743.1 EMG46342.1 - 0.00062 19.3 0.2 0.00079 19.0 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin DUF836 PF05768.9 EMG46342.1 - 0.0028 17.9 0.0 0.0038 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) AhpC-TSA PF00578.16 EMG46342.1 - 0.0032 17.1 0.2 0.37 10.4 0.0 2.0 1 1 1 2 2 2 2 AhpC/TSA family Thioredoxin_3 PF13192.1 EMG46342.1 - 0.0066 16.2 0.0 0.0095 15.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain DIM1 PF02966.11 EMG46342.1 - 0.0072 15.8 0.3 0.0081 15.6 0.2 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 DUF2847 PF11009.3 EMG46342.1 - 0.015 14.8 0.1 0.02 14.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) HyaE PF07449.6 EMG46342.1 - 0.019 14.8 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.1 EMG46342.1 - 0.042 13.4 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin KaiA PF07688.7 EMG46342.1 - 0.1 11.8 0.8 0.12 11.6 0.5 1.1 1 0 0 1 1 1 0 KaiA domain Amidohydro_2 PF04909.9 EMG46343.1 - 1.2e-05 25.0 0.0 2.3e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase Ribosomal_L19 PF01245.15 EMG46344.1 - 4.5e-10 39.2 2.0 9.4e-10 38.2 1.4 1.6 1 1 0 1 1 1 1 Ribosomal protein L19 Peptidase_U9 PF03420.8 EMG46344.1 - 0.011 14.9 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 Prohead core protein protease CFEM PF05730.6 EMG46345.1 - 0.0015 18.2 5.1 0.0024 17.6 3.5 1.3 1 0 0 1 1 1 1 CFEM domain SPX PF03105.14 EMG46347.1 - 2.5e-40 139.0 20.0 2.5e-40 139.0 13.9 2.1 2 1 0 2 2 2 1 SPX domain zf-C3HC4_4 PF15227.1 EMG46347.1 - 4.5e-09 36.0 9.1 4.5e-09 36.0 6.3 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EMG46347.1 - 1.4e-08 34.4 8.2 2.8e-08 33.4 5.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMG46347.1 - 1.4e-08 34.5 10.1 1.4e-08 34.5 7.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMG46347.1 - 9.6e-08 31.5 6.9 1.7e-07 30.7 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMG46347.1 - 4.5e-07 29.4 8.5 4.5e-07 29.4 5.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMG46347.1 - 1.8e-06 27.5 7.2 3.9e-06 26.4 5.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMG46347.1 - 0.00012 21.7 6.8 0.00012 21.7 4.7 2.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_4 PF14570.1 EMG46347.1 - 0.0027 17.2 6.8 0.014 15.0 4.9 2.0 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EMG46347.1 - 0.022 14.8 3.0 0.056 13.5 2.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 EMG46347.1 - 0.074 12.6 5.4 0.23 11.0 3.7 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 EMG46347.1 - 0.086 12.6 2.1 0.18 11.6 1.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-MIZ PF02891.15 EMG46347.1 - 0.15 11.6 7.3 0.29 10.6 5.0 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger HsdM_N PF12161.3 EMG46347.1 - 0.64 10.4 11.4 0.29 11.5 5.6 2.2 2 0 0 2 2 2 0 HsdM N-terminal domain DZR PF12773.2 EMG46347.1 - 1.5 8.7 4.2 3.8 7.4 2.9 1.6 1 1 0 1 1 1 0 Double zinc ribbon WBS_methylT PF12589.3 EMG46348.1 - 3.1e-15 56.4 7.3 5.5e-15 55.6 5.1 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EMG46348.1 - 6.6e-12 45.7 0.0 1.3e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMG46348.1 - 4.2e-08 33.0 0.0 6.2e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMG46348.1 - 5.1e-07 29.9 0.0 2.9e-06 27.5 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMG46348.1 - 7.9e-07 29.4 0.1 2.2e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMG46348.1 - 0.0001 22.8 0.0 0.00023 21.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 EMG46348.1 - 0.00025 21.1 0.0 0.00058 19.9 0.0 1.6 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.1 EMG46348.1 - 0.00049 19.7 0.0 0.0012 18.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMG46348.1 - 0.0018 18.2 0.0 0.015 15.3 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EMG46348.1 - 0.0047 16.0 0.0 0.054 12.5 0.0 2.1 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EMG46348.1 - 0.051 12.6 0.0 0.086 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EMG46348.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Myosin_head PF00063.16 EMG46349.1 - 1.2e-240 800.2 16.2 1.2e-240 800.2 11.2 5.0 4 2 1 6 6 6 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 EMG46349.1 - 4.8e-07 27.9 208.6 2.7e-05 22.1 65.4 4.5 2 1 0 3 3 3 3 Myosin tail Peptidase_M16 PF00675.15 EMG46350.1 - 5e-35 120.4 0.0 9.1e-35 119.6 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EMG46350.1 - 8.9e-31 106.9 0.0 2.4e-30 105.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain RTX PF02382.10 EMG46350.1 - 0.051 11.8 0.2 0.072 11.3 0.2 1.1 1 0 0 1 1 1 0 RTX N-terminal domain DUF3112 PF11309.3 EMG46351.1 - 1.2e-50 171.3 16.5 1.4e-50 171.2 3.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) Cyclin_N PF00134.18 EMG46352.1 - 7.3e-40 135.4 4.5 1.7e-39 134.2 0.4 2.9 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMG46352.1 - 3.7e-07 30.0 0.1 3.7e-07 30.0 0.1 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain Recep_L_domain PF01030.19 EMG46352.1 - 0.0069 16.3 2.7 0.021 14.7 1.9 1.8 1 0 0 1 1 1 1 Receptor L domain Oxysterol_BP PF01237.13 EMG46353.1 - 1e-95 320.2 0.3 1.3e-95 319.9 0.2 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein PI3_PI4_kinase PF00454.22 EMG46354.1 - 3.3e-26 92.2 0.0 1.1e-25 90.5 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 EMG46354.1 - 2e-18 65.8 0.4 1e-17 63.5 0.3 2.4 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.15 EMG46354.1 - 2.1e-06 27.0 1.3 2.1e-06 27.0 0.9 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PAP_central PF04928.12 EMG46355.1 - 2.7e-109 363.8 0.0 3.9e-109 363.3 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EMG46355.1 - 1.8e-46 157.4 0.2 3.7e-46 156.5 0.1 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EMG46355.1 - 2.7e-12 46.8 0.1 9.3e-12 45.1 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap PF03813.9 EMG46355.1 - 0.019 12.5 0.1 0.32 8.4 0.0 2.1 2 0 0 2 2 2 0 Nrap protein Sec10 PF07393.6 EMG46357.1 - 1.4e-69 235.1 28.8 1.9e-69 234.6 20.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.28 EMG46357.1 - 9.9e-06 25.0 0.4 3e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 F-box domain ECH_C PF13766.1 EMG46357.1 - 0.012 15.7 0.0 0.049 13.7 0.0 2.1 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region F-box-like PF12937.2 EMG46357.1 - 0.075 12.7 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 F-box-like ABC_tran_2 PF12848.2 EMG46358.1 - 0.045 13.5 5.6 0.097 12.5 3.9 1.5 1 0 0 1 1 1 0 ABC transporter CT47 PF15623.1 EMG46358.1 - 0.062 13.0 8.8 0.072 12.8 6.1 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 Cpn60_TCP1 PF00118.19 EMG46359.1 - 4e-152 507.2 4.2 4.7e-152 507.0 2.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RVT_1 PF00078.22 EMG46360.1 - 1.3e-24 86.7 0.2 2.2e-24 86.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EMG46361.1 - 1.4e-14 54.2 0.0 2.3e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain AA_permease PF00324.16 EMG46362.1 - 3.5e-134 447.7 39.0 3.9e-134 447.5 27.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG46362.1 - 2.3e-43 148.3 43.4 2.8e-43 148.0 30.1 1.0 1 0 0 1 1 1 1 Amino acid permease Homeobox PF00046.24 EMG46363.1 - 5.9e-05 22.6 4.0 0.00014 21.3 2.8 1.7 1 0 0 1 1 1 1 Homeobox domain GDPD PF03009.12 EMG46363.1 - 0.00072 19.1 3.0 0.00087 18.8 1.9 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Homeobox_KN PF05920.6 EMG46363.1 - 0.0054 16.4 1.0 0.015 14.9 0.2 2.2 2 0 0 2 2 2 1 Homeobox KN domain PTPS PF01242.14 EMG46363.1 - 0.015 14.9 0.9 0.031 13.9 0.6 1.5 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase bZIP_Maf PF03131.12 EMG46363.1 - 0.25 11.6 4.6 0.26 11.6 1.0 2.5 3 0 0 3 3 3 0 bZIP Maf transcription factor Fungal_trans PF04082.13 EMG46364.1 - 2.2e-21 75.9 3.1 2.2e-21 75.9 2.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG46364.1 - 1.3e-07 31.3 11.2 2.8e-07 30.3 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AATF-Che1 PF13339.1 EMG46364.1 - 0.05 13.7 0.6 2.7 8.1 0.3 2.8 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Zn_clus PF00172.13 EMG46366.1 - 1.3e-10 41.0 13.0 2.4e-10 40.1 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4397 PF14344.1 EMG46366.1 - 0.085 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4397) TPR_11 PF13414.1 EMG46367.1 - 2.2e-59 197.0 29.7 2.7e-17 62.1 0.3 6.2 5 1 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 EMG46367.1 - 4.7e-48 158.9 28.2 2.6e-09 36.2 1.4 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 EMG46367.1 - 5e-39 129.0 28.3 5.7e-08 32.1 0.7 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.1 EMG46367.1 - 6e-26 90.5 11.1 8.6e-06 26.2 1.1 6.4 3 3 3 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 EMG46367.1 - 4e-23 81.1 20.4 1e-10 41.3 1.5 5.8 3 3 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMG46367.1 - 1.2e-22 78.2 7.2 0.00092 19.6 0.0 8.4 3 3 5 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 EMG46367.1 - 7.4e-18 62.9 32.5 4.9e-06 25.9 0.7 8.7 8 1 1 9 9 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 EMG46367.1 - 7.1e-17 61.5 21.3 0.00011 22.4 1.8 6.8 4 3 3 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 EMG46367.1 - 1.8e-15 55.4 11.2 0.0057 16.3 0.1 7.4 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 EMG46367.1 - 1.2e-14 53.1 18.8 0.046 13.9 0.1 8.3 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.1 EMG46367.1 - 6.8e-10 38.6 2.3 0.00037 20.2 0.0 5.3 4 1 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMG46367.1 - 1.5e-07 31.3 22.8 0.54 10.8 0.0 8.0 9 0 0 9 9 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMG46367.1 - 1.1e-05 25.1 7.3 5.4e-05 22.9 0.1 4.5 5 0 0 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 EMG46367.1 - 3.2e-05 23.9 19.8 0.024 14.7 0.8 4.5 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EMG46367.1 - 3.9e-05 23.4 5.0 0.34 10.9 0.1 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat Inhibitor_I9 PF05922.11 EMG46367.1 - 0.028 14.9 0.4 0.15 12.6 0.0 2.5 2 0 0 2 2 1 0 Peptidase inhibitor I9 DUF1101 PF06503.6 EMG46367.1 - 0.045 12.5 0.0 0.075 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1101) DUF3808 PF10300.4 EMG46367.1 - 0.089 11.3 3.0 0.074 11.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) PPR_2 PF13041.1 EMG46367.1 - 0.11 12.5 0.2 12 6.0 0.0 3.8 4 0 0 4 4 4 0 PPR repeat family TPR_21 PF09976.4 EMG46367.1 - 0.76 9.7 22.0 0.45 10.4 0.7 4.7 4 2 1 5 5 5 0 Tetratricopeptide repeat Sec5 PF15469.1 EMG46367.1 - 1.5 8.5 7.1 0.57 9.8 0.1 3.4 3 2 0 3 3 3 0 Exocyst complex component Sec5 SHNi-TPR PF10516.4 EMG46367.1 - 1.5 8.0 7.0 61 2.9 0.0 4.7 5 0 0 5 5 5 0 SHNi-TPR TOM20_plant PF06552.7 EMG46367.1 - 1.7 8.1 7.7 3.9 7.0 0.1 4.4 4 2 2 6 6 6 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_3 PF07720.7 EMG46367.1 - 1.8 8.4 20.4 3.4 7.5 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat MDH PF02315.11 EMG46367.1 - 2 8.3 6.2 6.6 6.7 3.2 2.7 2 0 0 2 2 2 0 Methanol dehydrogenase beta subunit bZIP_1 PF00170.16 EMG46368.1 - 3.2e-06 26.9 13.8 3.2e-06 26.9 9.6 3.0 4 0 0 4 4 4 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 EMG46368.1 - 0.0041 16.7 0.9 0.0086 15.6 0.6 1.5 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain Macoilin PF09726.4 EMG46368.1 - 0.0047 15.2 13.8 0.0058 14.9 9.6 1.1 1 0 0 1 1 1 1 Transmembrane protein TF_AP-2 PF03299.9 EMG46368.1 - 0.034 13.7 3.2 0.054 13.0 2.2 1.2 1 0 0 1 1 1 0 Transcription factor AP-2 bZIP_Maf PF03131.12 EMG46368.1 - 0.41 10.9 13.3 0.3 11.4 7.7 1.9 1 1 0 1 1 1 0 bZIP Maf transcription factor RHH_4 PF13467.1 EMG46369.1 - 0.035 13.9 0.0 0.089 12.6 0.0 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix domain DUF605 PF04652.11 EMG46369.1 - 0.17 11.2 17.1 0.9 8.8 1.6 2.1 2 0 0 2 2 2 0 Vta1 like BUD22 PF09073.5 EMG46369.1 - 4.5 6.2 15.3 0.033 13.2 4.7 1.7 2 0 0 2 2 2 0 BUD22 Zn_clus PF00172.13 EMG46370.1 - 3.1e-09 36.5 15.2 5.8e-09 35.7 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC45 PF02724.9 EMG46370.1 - 1.4 6.8 7.5 2.3 6.1 5.2 1.3 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.8 EMG46370.1 - 4.7 4.8 13.1 7.8 4.1 9.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi FAD_binding_8 PF08022.7 EMG46371.1 - 9.7e-26 89.6 0.2 2.2e-25 88.5 0.1 1.7 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 EMG46371.1 - 1.7e-25 89.7 0.0 3.2e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMG46371.1 - 6.3e-19 68.3 12.2 6.3e-19 68.3 8.5 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EMG46371.1 - 0.13 12.8 0.0 1.9 9.1 0.0 2.4 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain CFEM PF05730.6 EMG46371.1 - 1.7 8.5 7.5 3 7.7 5.2 1.3 1 0 0 1 1 1 0 CFEM domain ETF_QO PF05187.8 EMG46372.1 - 2.5e-41 140.0 0.0 5.4e-41 139.0 0.0 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EMG46372.1 - 2.4e-09 36.5 0.0 9.7e-05 21.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMG46372.1 - 2.4e-08 33.2 0.1 0.00081 18.3 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EMG46372.1 - 6.6e-07 28.6 0.0 0.00053 19.1 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.1 EMG46372.1 - 7e-05 22.7 0.0 0.00018 21.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMG46372.1 - 7.8e-05 22.8 0.0 0.00025 21.1 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMG46372.1 - 0.00015 20.3 0.3 0.0038 15.7 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 EMG46372.1 - 0.00028 20.0 0.1 0.00097 18.2 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMG46372.1 - 0.00048 20.0 0.0 0.00082 19.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 EMG46372.1 - 0.0069 16.7 0.6 0.018 15.4 0.4 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox PF00070.22 EMG46372.1 - 0.0096 16.3 0.1 7.6 7.0 0.0 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMG46372.1 - 0.018 14.7 0.1 0.037 13.7 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 EMG46372.1 - 0.029 13.3 0.0 0.062 12.2 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 EMG46372.1 - 0.03 13.2 0.1 0.042 12.7 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.2 EMG46372.1 - 0.068 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase RhoGEF PF00621.15 EMG46373.1 - 5.4e-37 127.4 1.1 2.4e-36 125.3 0.7 2.2 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.6 EMG46373.1 - 3.1e-36 123.2 0.7 3.1e-36 123.2 0.5 2.2 2 0 0 2 2 2 1 CDC24 Calponin PH_10 PF15411.1 EMG46373.1 - 7.9e-22 77.6 0.5 8e-21 74.3 0.3 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.19 EMG46373.1 - 6.2e-07 28.9 0.2 2.3e-06 27.1 0.1 2.0 1 0 0 1 1 1 1 PB1 domain DUF2693 PF10902.3 EMG46373.1 - 0.052 13.4 0.4 1.3 8.9 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2693) EF-hand_6 PF13405.1 EMG46374.1 - 0.0042 16.8 0.0 0.073 12.9 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 EMG46374.1 - 0.0058 16.7 0.9 0.13 12.3 0.0 2.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EMG46374.1 - 0.027 13.7 0.0 0.58 9.5 0.0 2.7 2 0 0 2 2 2 0 EF hand DUF498 PF04430.9 EMG46374.1 - 0.24 10.9 1.2 7.7 6.1 0.1 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF498/DUF598) LRR_4 PF12799.2 EMG46375.1 - 3.8e-11 42.3 37.1 0.00017 21.0 0.3 8.7 7 2 2 9 9 9 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG46375.1 - 4.3e-10 39.2 29.1 7.8e-05 22.3 0.1 6.5 6 1 1 7 7 7 3 Leucine rich repeat FNIP PF05725.7 EMG46375.1 - 0.1 12.5 0.1 0.1 12.5 0.0 6.6 8 0 0 8 8 8 0 FNIP Repeat Pex24p PF06398.6 EMG46376.1 - 2.3e-53 181.2 17.0 3.6e-53 180.6 11.8 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Noelin-1 PF12308.3 EMG46376.1 - 0.0085 15.8 0.1 0.032 14.0 0.1 2.0 1 0 0 1 1 1 1 Neurogenesis glycoprotein TraT PF05818.7 EMG46376.1 - 0.022 14.1 0.3 0.052 12.9 0.2 1.5 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein SIR2 PF02146.12 EMG46377.1 - 1.7e-36 125.6 0.1 3.4e-34 118.1 0.0 3.0 2 1 0 2 2 2 1 Sir2 family BLOC1_2 PF10046.4 EMG46377.1 - 0.014 15.4 4.9 0.028 14.5 0.1 3.2 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Pkinase PF00069.20 EMG46378.1 - 3e-76 256.0 0.0 5.2e-76 255.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG46378.1 - 1.2e-37 129.4 0.0 1.9e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EMG46378.1 - 4.5e-20 71.5 1.2 4.5e-20 71.5 0.8 1.8 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EMG46378.1 - 1.7e-08 33.8 0.0 3.3e-08 32.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like YukC PF10140.4 EMG46378.1 - 0.0001 21.0 0.2 0.00015 20.4 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC UBA_3 PF09288.5 EMG46378.1 - 0.0052 16.3 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain DUF2443 PF10398.4 EMG46378.1 - 0.0076 16.0 1.6 0.016 15.0 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2443) Kdo PF06293.9 EMG46378.1 - 0.0095 15.0 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Innate_immun PF12782.2 EMG46378.1 - 0.4 9.8 9.1 0.62 9.2 6.3 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Cyclin_N PF00134.18 EMG46379.1 - 3.7e-33 113.7 0.5 5.7e-33 113.1 0.4 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain eIF3_p135 PF12807.2 EMG46379.1 - 0.036 14.0 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 Cupin_8 PF13621.1 EMG46380.1 - 7.4e-53 179.6 0.0 5.2e-52 176.8 0.0 1.9 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EMG46380.1 - 2.8e-07 30.1 0.0 2.8e-05 23.5 0.0 2.6 2 0 0 2 2 2 2 Cupin superfamily protein Cupin_2 PF07883.6 EMG46380.1 - 0.11 11.9 0.0 10 5.7 0.0 2.5 2 0 0 2 2 2 0 Cupin domain OTU PF02338.14 EMG46381.1 - 6.3e-17 62.2 0.0 6.3e-17 62.2 0.0 2.2 2 1 0 2 2 2 1 OTU-like cysteine protease RNA_pol_Rpb2_6 PF00562.23 EMG46381.1 - 0.013 14.3 4.7 0.014 14.1 3.3 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 ISG65-75 PF11727.3 EMG46381.1 - 0.2 10.6 12.1 0.35 9.8 8.4 1.4 1 0 0 1 1 1 0 Invariant surface glycoprotein YABBY PF04690.8 EMG46381.1 - 0.3 11.3 5.6 0.56 10.4 3.9 1.4 1 0 0 1 1 1 0 YABBY protein DUF1878 PF08963.5 EMG46381.1 - 0.97 9.6 6.4 1.3 9.2 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1878) DUF342 PF03961.8 EMG46381.1 - 1.5 7.1 14.2 2.3 6.5 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4559 PF15112.1 EMG46381.1 - 2.3 7.3 17.2 0.026 13.7 4.1 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4559) DUF883 PF05957.8 EMG46381.1 - 3.7 8.0 9.4 37 4.8 0.9 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DDE_3 PF13358.1 EMG46382.1 - 3.7e-07 29.9 0.0 7.6e-07 28.9 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease Erf4 PF10256.4 EMG46383.1 - 9.8e-30 102.8 0.1 1.5e-29 102.2 0.1 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family PPR_2 PF13041.1 EMG46384.1 - 8.8e-06 25.6 10.8 0.3 11.0 0.0 6.4 7 0 0 7 7 7 3 PPR repeat family YfiO PF13525.1 EMG46384.1 - 4.4e-05 23.0 3.8 0.013 14.9 0.0 2.5 2 0 0 2 2 2 2 Outer membrane lipoprotein TPR_16 PF13432.1 EMG46384.1 - 9.1e-05 23.0 0.0 0.0014 19.2 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat PPR PF01535.15 EMG46384.1 - 0.0003 20.5 12.4 1.7 8.7 0.0 6.7 8 0 0 8 8 8 2 PPR repeat TPR_14 PF13428.1 EMG46384.1 - 0.00077 19.8 0.0 4.5 8.1 0.0 4.2 3 1 1 4 4 3 1 Tetratricopeptide repeat PPR_3 PF13812.1 EMG46384.1 - 0.0011 19.0 0.0 7.1 7.1 0.0 5.2 5 0 0 5 5 5 1 Pentatricopeptide repeat domain TPR_19 PF14559.1 EMG46384.1 - 0.0014 18.8 0.6 0.066 13.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMG46384.1 - 0.0022 18.3 5.2 0.23 11.9 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat SPOB_a PF14689.1 EMG46384.1 - 0.023 14.2 3.5 5 6.7 0.0 4.5 4 1 1 5 5 5 0 Sensor_kinase_SpoOB-type, alpha-helical domain BTAD PF03704.12 EMG46384.1 - 0.041 14.1 0.0 5 7.4 0.0 2.5 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_8 PF13181.1 EMG46384.1 - 0.13 12.1 5.6 20 5.2 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat Cyto_heme_lyase PF01265.12 EMG46385.1 - 3.3e-73 246.4 0.1 5.8e-73 245.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Dynamin_M PF01031.15 EMG46386.1 - 5.9e-105 350.2 0.1 5.9e-105 350.2 0.1 1.5 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EMG46386.1 - 3.5e-55 186.3 0.1 6.9e-55 185.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EMG46386.1 - 1.5e-27 95.3 4.4 1.5e-27 95.3 3.0 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EMG46386.1 - 0.0011 18.9 0.3 0.011 15.6 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMG46386.1 - 0.043 14.3 0.1 0.14 12.7 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein Macro PF01661.16 EMG46387.1 - 1.6e-27 95.7 0.0 1.9e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Macro domain Tub_2 PF04525.7 EMG46388.1 - 0.12 11.6 0.0 0.35 10.2 0.0 1.7 2 0 0 2 2 2 0 Tubby C 2 TruB_N PF01509.13 EMG46389.1 - 3.2e-44 150.6 0.1 1.8e-43 148.2 0.1 2.1 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PseudoU_synth_2 PF00849.17 EMG46389.1 - 0.03 14.1 0.1 0.048 13.4 0.1 1.5 1 1 0 1 1 1 0 RNA pseudouridylate synthase DUF111 PF01969.12 EMG46389.1 - 0.23 10.2 0.0 0.23 10.2 0.0 2.4 3 1 0 3 3 3 0 Protein of unknown function DUF111 Aldose_epim PF01263.15 EMG46390.1 - 1.1e-42 146.2 0.2 1.4e-42 145.9 0.2 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase PAP2 PF01569.16 EMG46393.1 - 1.8e-12 47.0 4.6 1.8e-12 47.0 3.2 2.4 2 1 1 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.1 EMG46393.1 - 2e-06 27.4 3.7 2e-06 27.4 2.5 2.2 2 0 0 2 2 2 1 PAP2 superfamily POLO_box PF00659.13 EMG46394.1 - 0.045 13.7 0.2 0.73 9.8 0.1 2.5 1 1 1 2 2 2 0 POLO box duplicated region DUF605 PF04652.11 EMG46395.1 - 0.21 10.9 16.6 0.32 10.3 11.5 1.2 1 0 0 1 1 1 0 Vta1 like MFS_1 PF07690.11 EMG46397.1 - 4.9e-32 111.0 17.9 5.7e-32 110.7 12.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG46397.1 - 1.1e-13 50.6 16.5 1.4e-13 50.2 11.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EMG46397.1 - 1.2e-05 23.7 7.6 1.4e-05 23.5 5.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF997 PF06196.7 EMG46397.1 - 0.006 16.0 0.2 0.016 14.6 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF997) ATG22 PF11700.3 EMG46397.1 - 0.43 9.0 12.0 0.53 8.7 8.0 1.3 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like OATP PF03137.15 EMG46397.1 - 1.6 6.7 12.5 0.046 11.7 2.0 2.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family LRR_4 PF12799.2 EMG46398.1 - 3.2e-10 39.4 25.0 5.1e-08 32.3 1.5 10.5 7 2 3 10 10 10 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG46398.1 - 5.3e-10 38.9 20.2 3.5e-06 26.6 4.0 8.3 7 2 2 9 9 9 4 Leucine rich repeat LRR_1 PF00560.28 EMG46398.1 - 0.0014 18.3 2.1 0.034 14.1 0.1 11.6 10 4 2 12 12 12 2 Leucine Rich Repeat LRR_6 PF13516.1 EMG46398.1 - 0.17 12.0 0.1 0.17 12.0 0.1 10.7 14 0 0 14 14 14 0 Leucine Rich repeat Git3_C PF11970.3 EMG46399.1 - 3.2e-35 119.7 4.0 6.6e-35 118.7 2.8 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Git3 PF11710.3 EMG46399.1 - 1.9e-11 43.9 3.9 3.5e-11 43.0 2.7 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 FAM176 PF14851.1 EMG46399.1 - 0.79 9.3 6.9 0.25 11.0 2.4 1.9 2 0 0 2 2 2 0 FAM176 family YTH PF04146.10 EMG46401.1 - 1.7e-42 144.3 0.2 3.1e-42 143.4 0.2 1.4 1 0 0 1 1 1 1 YT521-B-like domain COQ7 PF03232.8 EMG46402.1 - 4.5e-78 260.6 0.1 5.9e-78 260.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 EMG46402.1 - 0.021 15.1 0.1 0.085 13.1 0.0 2.0 2 0 0 2 2 2 0 Rubrerythrin Nefa_Nip30_N PF10187.4 EMG46402.1 - 0.077 13.1 1.0 0.2 11.8 0.7 1.6 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 SRP54 PF00448.17 EMG46402.1 - 0.11 11.8 0.1 7.7 5.9 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Nuf2 PF03800.9 EMG46403.1 - 3.6e-34 117.8 2.7 4.7e-34 117.4 0.0 2.5 2 1 0 2 2 2 1 Nuf2 family Z1 PF10593.4 EMG46403.1 - 0.67 9.1 25.5 1.8 7.7 1.4 3.8 2 1 2 4 4 4 0 Z1 domain Reo_sigmaC PF04582.7 EMG46403.1 - 2.5 7.1 7.7 1.2 8.2 3.0 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein PseudoU_synth_1 PF01416.15 EMG46405.1 - 1.6e-30 105.6 0.0 1.8e-19 70.1 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF4284 PF14112.1 EMG46405.1 - 0.041 14.3 0.4 0.11 12.9 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4284) TIMELESS PF04821.9 EMG46406.1 - 1.3e-45 155.7 13.6 1.5e-45 155.5 5.4 3.0 2 1 0 2 2 2 1 Timeless protein Aa_trans PF01490.13 EMG46407.1 - 8.6e-29 100.2 12.9 1.1e-28 99.8 8.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PWI PF01480.12 EMG46407.1 - 7.5e-16 58.0 0.1 1.4e-15 57.0 0.1 1.5 1 0 0 1 1 1 1 PWI domain Trp_Tyr_perm PF03222.8 EMG46407.1 - 0.00085 18.2 7.7 0.0012 17.7 5.3 1.2 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family TMEM247 PF15444.1 EMG46407.1 - 0.0025 17.6 0.5 0.0041 16.9 0.3 1.2 1 0 0 1 1 1 1 Transmembrane protein 247 Sdh_cyt PF01127.17 EMG46407.1 - 0.15 11.9 4.6 0.95 9.3 0.8 2.3 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Y_phosphatase3 PF13350.1 EMG46408.1 - 8.4e-47 159.4 0.0 2e-46 158.2 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Abhydrolase_5 PF12695.2 EMG46408.1 - 1.2e-11 44.6 0.0 1.8e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMG46408.1 - 1.9e-11 44.3 0.0 4e-11 43.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Y_phosphatase3C PF13348.1 EMG46408.1 - 1.1e-07 31.8 0.0 3.4e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Peptidase_S9 PF00326.16 EMG46408.1 - 0.00011 21.4 0.1 0.032 13.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Y_phosphatase2 PF03162.8 EMG46408.1 - 0.00083 18.7 0.0 0.002 17.5 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Hydrolase_4 PF12146.3 EMG46408.1 - 0.005 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 EMG46408.1 - 0.0084 15.4 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Y_phosphatase PF00102.22 EMG46408.1 - 0.024 13.9 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EMG46408.1 - 0.093 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate Ctf8 PF09696.5 EMG46409.1 - 2.4e-35 120.9 0.0 3e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Ctf8 Rpr2 PF04032.11 EMG46410.1 - 2.2e-12 46.6 0.8 2.2e-12 46.6 0.6 1.7 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Cas_Cmr5 PF09701.5 EMG46410.1 - 0.17 12.0 2.2 1.6 8.9 1.2 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cmr5) TMEM237 PF15383.1 EMG46410.1 - 0.19 10.8 3.0 0.3 10.2 2.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 Nudix_N_2 PF14803.1 EMG46410.1 - 0.37 10.5 2.5 15 5.3 0.1 2.5 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_2 PF13240.1 EMG46410.1 - 0.81 9.2 2.8 0.58 9.7 0.3 1.9 2 0 0 2 2 2 0 zinc-ribbon domain Zn_clus PF00172.13 EMG46411.1 - 2.2e-08 33.8 9.3 3.9e-08 33.0 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Daxx PF03344.10 EMG46411.1 - 0.051 12.0 0.2 0.073 11.5 0.1 1.1 1 0 0 1 1 1 0 Daxx Family DUF1620 PF07774.8 EMG46412.1 - 1.7e-66 223.5 5.2 2.1e-66 223.3 2.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1620) RPAP1_C PF08620.5 EMG46413.1 - 4.5e-33 112.9 0.2 4.5e-33 112.9 0.1 2.8 3 0 0 3 3 3 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EMG46413.1 - 4.2e-18 64.6 9.4 1.3e-17 63.1 6.5 1.9 1 0 0 1 1 1 1 RPAP1-like, N-terminal RRXRR PF14239.1 EMG46414.1 - 0.018 14.4 0.9 0.031 13.6 0.6 1.3 1 0 0 1 1 1 0 RRXRR protein Peptidase_S10 PF00450.17 EMG46415.1 - 1.5e-113 380.0 0.7 1.9e-113 379.7 0.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EMG46415.1 - 0.0008 19.3 0.0 0.0056 16.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMG46415.1 - 0.0012 18.1 0.7 0.48 9.6 0.0 2.9 3 1 0 3 3 3 2 Prolyl oligopeptidase family Rep_fac_C PF08542.6 EMG46416.1 - 1.4e-15 57.0 0.0 3.3e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 EMG46416.1 - 5.8e-14 52.4 0.0 1.1e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EMG46416.1 - 8e-14 51.6 0.1 2.3e-12 46.8 0.1 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EMG46416.1 - 6.6e-10 38.2 0.1 9.2e-08 31.2 0.0 2.1 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EMG46416.1 - 1.7e-06 27.2 0.0 3.6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EMG46416.1 - 9.4e-06 24.5 0.0 0.056 12.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_22 PF13401.1 EMG46416.1 - 1e-05 25.6 1.0 0.00016 21.8 0.1 2.7 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EMG46416.1 - 9.3e-05 22.4 0.0 0.00025 21.0 0.0 1.7 2 1 1 3 3 1 1 AAA ATPase domain AAA_11 PF13086.1 EMG46416.1 - 0.00011 21.9 0.0 0.00036 20.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMG46416.1 - 0.00011 21.8 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 EMG46416.1 - 0.00017 20.5 0.0 0.00028 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_30 PF13604.1 EMG46416.1 - 0.00028 20.5 0.0 0.00059 19.4 0.0 1.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EMG46416.1 - 0.00033 19.8 0.0 0.0013 17.8 0.0 1.9 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EMG46416.1 - 0.00058 19.7 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EMG46416.1 - 0.00065 19.2 0.1 0.31 10.4 0.0 2.5 1 1 1 2 2 2 1 AAA-like domain DNA_pol3_delta PF06144.8 EMG46416.1 - 0.00067 19.2 0.4 0.0012 18.4 0.3 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DUF2075 PF09848.4 EMG46416.1 - 0.0015 17.5 0.0 0.0022 17.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 EMG46416.1 - 0.0033 18.2 0.2 0.019 15.7 0.0 2.3 1 1 0 2 2 2 1 AAA domain ResIII PF04851.10 EMG46416.1 - 0.0038 17.0 0.0 0.018 14.8 0.0 1.9 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_5 PF07728.9 EMG46416.1 - 0.0038 16.9 0.8 0.09 12.5 0.1 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EMG46416.1 - 0.0066 15.8 0.0 0.083 12.2 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EMG46416.1 - 0.0089 16.3 0.0 0.026 14.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.1 EMG46416.1 - 0.017 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 EMG46416.1 - 0.03 13.8 0.1 0.32 10.4 0.0 2.2 1 1 0 2 2 2 0 DEAD/DEAH box helicase GPAT_N PF14829.1 EMG46416.1 - 0.037 13.6 0.0 0.78 9.4 0.0 2.4 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal AAA_28 PF13521.1 EMG46416.1 - 0.039 13.9 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EMG46416.1 - 0.056 12.8 0.0 0.26 10.6 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.17 EMG46416.1 - 0.06 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 EMG46416.1 - 0.06 13.2 0.0 0.15 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain Bet_v_1 PF00407.14 EMG46416.1 - 0.096 12.2 0.0 0.28 10.8 0.0 1.7 2 0 0 2 2 2 0 Pathogenesis-related protein Bet v I family Mid1 PF12929.2 EMG46417.1 - 6.8e-151 502.8 12.0 9e-151 502.4 8.3 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 EMG46417.1 - 0.058 13.7 2.3 1.2 9.5 0.2 2.4 2 0 0 2 2 2 0 Fz domain ThiF PF00899.16 EMG46418.1 - 3.2e-12 46.4 0.0 1.2e-11 44.5 0.0 2.0 2 0 0 2 2 2 1 ThiF family DEAD PF00270.24 EMG46419.1 - 8.1e-39 132.8 0.0 8.1e-39 132.8 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG46419.1 - 1.1e-20 73.1 0.0 3e-20 71.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EMG46419.1 - 4e-17 61.5 0.2 7.4e-17 60.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) UvrD-helicase PF00580.16 EMG46419.1 - 0.043 13.0 7.7 0.56 9.4 0.0 2.5 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain IncA PF04156.9 EMG46419.1 - 2.8 7.4 5.8 4.7 6.7 4.0 1.3 1 0 0 1 1 1 0 IncA protein DUF445 PF04286.7 EMG46420.1 - 2.5 7.5 10.3 1.2 8.5 5.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF445) DUF2404 PF10296.4 EMG46421.1 - 2.9e-30 104.2 0.4 1.5e-29 101.9 0.0 2.5 3 0 0 3 3 3 1 Putative integral membrane protein conserved region (DUF2404) PH_11 PF15413.1 EMG46421.1 - 2.2e-11 43.9 1.9 5.2e-11 42.7 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EMG46421.1 - 1e-08 35.2 2.5 3.7e-07 30.3 0.1 2.9 1 1 1 2 2 2 1 PH domain DUF4199 PF13858.1 EMG46421.1 - 0.037 13.9 0.1 0.099 12.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) TMEM171 PF15471.1 EMG46421.1 - 0.085 11.6 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 CTP_transf_1 PF01148.15 EMG46422.1 - 5.6e-78 262.1 21.9 7.3e-78 261.7 15.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family SUI1 PF01253.17 EMG46423.1 - 1.6e-30 104.6 1.4 2.2e-30 104.2 1.0 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Phage_hub_GP28 PF11110.3 EMG46423.1 - 0.052 13.2 0.1 0.062 12.9 0.0 1.1 1 0 0 1 1 1 0 Baseplate hub distal subunit Cas_Csa5 PF09702.5 EMG46423.1 - 0.082 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) CWC25 PF12542.3 EMG46424.1 - 3.6e-15 56.1 2.9 3.6e-15 56.1 2.0 2.3 1 1 1 2 2 2 1 Pre-mRNA splicing factor Cir_N PF10197.4 EMG46424.1 - 1.3e-12 47.5 12.5 1.3e-12 47.5 8.7 2.3 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR CKS PF01111.14 EMG46425.1 - 8.5e-36 121.6 0.2 1.1e-35 121.2 0.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit PI3_PI4_kinase PF00454.22 EMG46426.1 - 4.4e-47 160.5 0.1 1.3e-46 159.0 0.1 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.8 EMG46426.1 - 3.3e-24 84.9 1.4 5.4e-23 80.9 1.3 3.1 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.15 EMG46426.1 - 6.5e-15 54.2 0.0 1.9e-14 52.7 0.0 1.9 1 0 0 1 1 1 1 FATC domain FAT PF02259.18 EMG46426.1 - 1.7e-13 50.3 8.6 1.7e-13 50.3 6.0 3.4 3 1 0 3 3 3 1 FAT domain TPR_20 PF14561.1 EMG46426.1 - 0.0083 16.2 0.6 0.047 13.8 0.4 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Glyco_hydro_18 PF00704.23 EMG46427.1 - 1.6e-20 73.8 2.1 1.4e-19 70.8 0.1 2.4 2 1 1 3 3 3 2 Glycosyl hydrolases family 18 Flocculin_t3 PF13928.1 EMG46427.1 - 2.6e-14 53.0 21.0 2.6e-14 53.0 14.6 5.7 3 1 0 3 3 3 1 Flocculin type 3 repeat DUF706 PF05153.10 EMG46428.1 - 5.3e-127 422.3 6.0 6.9e-127 421.9 4.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 EMG46428.1 - 0.039 13.9 0.0 0.84 9.6 0.0 2.6 2 0 0 2 2 2 0 HD domain SAGA-Tad1 PF12767.2 EMG46429.1 - 0.31 10.6 14.7 0.51 9.9 10.2 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Trypsin_2 PF13365.1 EMG46429.1 - 0.32 10.9 0.0 0.32 10.9 0.0 2.7 2 1 0 2 2 2 0 Trypsin-like peptidase domain TFIIA PF03153.8 EMG46429.1 - 6.5 6.5 42.8 9.4 6.0 29.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mito_carr PF00153.22 EMG46430.1 - 4.2e-09 36.0 0.3 0.034 13.8 0.0 3.6 4 0 0 4 4 4 3 Mitochondrial carrier protein Arteri_Gl PF00951.13 EMG46430.1 - 0.037 13.6 0.2 0.065 12.8 0.1 1.3 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein Dpy-30 PF05186.8 EMG46431.1 - 2.7e-13 49.1 0.0 4.1e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif Pneumo_att_G PF05539.6 EMG46431.1 - 0.099 11.9 2.2 0.11 11.8 1.5 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Syntaxin-6_N PF09177.6 EMG46432.1 - 1e-17 64.3 0.7 1e-17 64.3 0.5 2.3 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EMG46432.1 - 1.2e-13 50.4 7.2 1.2e-13 50.4 5.0 2.2 2 0 0 2 2 2 1 SNARE domain DUF1640 PF07798.6 EMG46432.1 - 0.0065 16.5 4.3 0.029 14.4 3.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) DUF3040 PF11239.3 EMG46432.1 - 0.11 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Sec20 PF03908.8 EMG46432.1 - 0.4 10.4 5.9 0.18 11.5 0.4 2.3 2 0 0 2 2 2 0 Sec20 Laminin_II PF06009.7 EMG46432.1 - 0.75 9.5 6.2 5.7 6.7 0.4 3.0 2 1 1 3 3 3 0 Laminin Domain II V_ATPase_I PF01496.14 EMG46432.1 - 0.89 7.3 4.7 3.5 5.3 0.1 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family WXG100 PF06013.7 EMG46432.1 - 3.2 7.8 10.8 5.5 7.0 0.0 3.5 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF3219 PF11514.3 EMG46433.1 - 0.14 12.0 4.0 0.23 11.3 0.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3219) Pkinase PF00069.20 EMG46434.1 - 1.1e-71 241.0 0.0 1.1e-71 241.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG46434.1 - 7.9e-48 162.7 0.0 1.4e-47 161.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EMG46434.1 - 1.3e-18 67.1 0.0 1.3e-18 67.1 0.0 4.0 3 1 0 3 3 3 1 P21-Rho-binding domain Kinase-like PF14531.1 EMG46434.1 - 2.3e-05 23.4 0.0 4.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMG46434.1 - 0.012 15.4 2.2 0.17 11.5 0.0 3.1 2 2 1 3 3 3 0 Phosphotransferase enzyme family DUF2424 PF10340.4 EMG46435.1 - 2.8e-29 101.8 0.1 4.1e-29 101.3 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 EMG46435.1 - 4.4e-18 65.6 0.0 7.2e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMG46435.1 - 0.00071 19.3 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Metallophos PF00149.23 EMG46435.1 - 0.042 13.2 1.9 0.17 11.2 0.3 2.4 1 1 0 2 2 2 0 Calcineurin-like phosphoesterase Abhydrolase_6 PF12697.2 EMG46435.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3012 PF11216.3 EMG46435.1 - 0.47 10.1 4.7 0.1 12.2 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) Bac_luciferase PF00296.15 EMG46436.1 - 5.4e-54 183.3 0.0 7.4e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase PH PF00169.24 EMG46437.1 - 6.5e-17 61.6 8.2 1.5e-10 41.1 2.4 2.7 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EMG46437.1 - 2.2e-10 40.7 11.6 1.5e-05 25.1 3.3 4.1 2 2 1 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.1 EMG46437.1 - 1.6e-06 28.0 2.4 3.3e-05 23.8 0.8 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain Mcp5_PH PF12814.2 EMG46437.1 - 0.00032 20.6 3.3 0.072 13.0 0.0 3.0 2 1 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology CheF-arch PF04283.7 EMG46437.1 - 0.0025 17.0 0.1 0.0061 15.7 0.0 1.6 2 0 0 2 2 2 1 Chemotaxis signal transduction system protein F from archaea NOA36 PF06524.7 EMG46437.1 - 0.037 13.2 5.2 0.065 12.4 3.6 1.4 1 0 0 1 1 1 0 NOA36 protein PH_9 PF15410.1 EMG46437.1 - 1.7 8.8 8.6 3 8.0 2.7 3.4 2 2 1 3 3 3 0 Pleckstrin homology domain Smr PF01713.16 EMG46438.1 - 2.5e-14 53.1 0.1 5.1e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 EMG46438.1 - 7.2e-09 34.9 1.0 3e-07 29.7 0.0 3.0 2 0 0 2 2 2 1 CUE domain APG12 PF04110.8 EMG46438.1 - 0.13 12.4 1.1 0.39 10.9 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 RP-C_C PF11800.3 EMG46438.1 - 0.38 10.4 0.0 0.38 10.4 0.0 2.5 3 0 0 3 3 3 0 Replication protein C C-terminal region CTDII PF01556.13 EMG46439.1 - 9.3e-27 92.7 8.4 1e-21 76.5 0.7 3.6 3 1 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EMG46439.1 - 2.1e-22 78.6 7.3 3.9e-22 77.7 5.1 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EMG46439.1 - 3.7e-12 46.1 20.5 5.9e-12 45.4 14.2 1.3 1 0 0 1 1 1 1 DnaJ central domain Cytochrome_C7 PF14522.1 EMG46439.1 - 1.2 8.7 15.8 0.16 11.6 7.4 2.1 1 1 1 2 2 2 0 Cytochrome c7 HypA PF01155.14 EMG46439.1 - 1.3 8.7 9.4 2.5 7.8 1.0 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 EMG46439.1 - 9.8 6.5 12.4 27 5.1 8.4 1.9 1 1 0 1 1 1 0 Cytochrome c3 polyprenyl_synt PF00348.12 EMG46440.1 - 2.3e-32 111.9 0.0 2.8e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase DUF4403 PF14356.1 EMG46441.1 - 0.0046 15.3 0.1 0.008 14.5 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4403) GDE_C PF06202.9 EMG46441.1 - 0.054 12.2 1.3 0.26 9.9 0.7 1.8 1 1 1 2 2 2 0 Amylo-alpha-1,6-glucosidase Phage_lysozyme PF00959.14 EMG46441.1 - 0.15 12.3 0.6 0.24 11.6 0.4 1.4 1 0 0 1 1 1 0 Phage lysozyme Abhydrolase_2 PF02230.11 EMG46441.1 - 0.17 11.2 0.3 0.31 10.4 0.2 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Stn1 PF10451.4 EMG46441.1 - 0.19 10.5 3.0 0.27 10.0 2.1 1.1 1 0 0 1 1 1 0 Telomere regulation protein Stn1 MCPVI PF02993.9 EMG46441.1 - 1.7 8.7 6.2 2.3 8.3 4.3 1.2 1 0 0 1 1 1 0 Minor capsid protein VI TP_methylase PF00590.15 EMG46442.1 - 2.9e-15 56.5 0.0 4.7e-15 55.8 0.0 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DER1 PF04511.10 EMG46443.1 - 1.8e-18 66.7 9.0 1.2e-17 64.1 6.3 2.2 1 1 0 1 1 1 1 Der1-like family Hydrolase_6 PF13344.1 EMG46444.1 - 2.9e-22 78.4 0.0 5.9e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMG46444.1 - 1.1e-14 53.8 0.0 3.9e-13 48.9 0.0 3.0 2 1 0 2 2 2 1 HAD-hyrolase-like Imm11 PF15563.1 EMG46444.1 - 0.01 14.9 0.6 0.019 14.0 0.1 1.7 2 0 0 2 2 2 0 Immunity protein 11 Bacteriocin_IIc PF10439.4 EMG46445.1 - 0.013 15.6 4.5 0.017 15.2 3.2 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide SSP160 PF06933.6 EMG46445.1 - 0.78 7.6 11.2 0.8 7.6 7.7 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Gly-zipper_OmpA PF13436.1 EMG46445.1 - 4.9 6.8 9.5 5.7 6.6 6.6 1.1 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Fcf1 PF04900.7 EMG46446.1 - 3.6e-37 126.4 2.0 9.1e-37 125.2 0.5 2.1 1 1 1 2 2 2 1 Fcf1 Peptidase_M18 PF02127.10 EMG46447.1 - 4.3e-105 351.7 0.0 5e-105 351.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) 2-Hacid_dh_C PF02826.14 EMG46448.1 - 1.6e-35 121.8 0.0 6.5e-35 119.8 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMG46448.1 - 2e-14 53.2 0.0 2.7e-14 52.7 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMG46448.1 - 0.01 15.7 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EMG46448.1 - 0.025 14.6 0.0 1.4 9.0 0.0 2.8 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Put_Phosphatase PF06888.7 EMG46449.1 - 0.0064 15.6 0.3 0.012 14.7 0.2 1.4 1 0 0 1 1 1 1 Putative Phosphatase Guanylate_kin PF00625.16 EMG46450.1 - 4.6e-69 231.5 0.0 5.2e-69 231.3 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 EMG46450.1 - 1.3e-06 28.4 0.1 8.3e-06 25.9 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMG46450.1 - 4.1e-06 26.9 0.0 2e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EMG46450.1 - 4.8e-06 26.5 0.0 1.4e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMG46450.1 - 9e-06 26.5 0.1 1.9e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMG46450.1 - 5.1e-05 23.5 0.5 0.00026 21.3 0.1 2.3 1 1 1 2 2 1 1 AAA domain AAA_14 PF13173.1 EMG46450.1 - 0.00018 21.3 0.0 0.00036 20.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EMG46450.1 - 0.00043 20.6 0.0 0.00054 20.2 0.0 1.6 1 1 0 1 1 1 1 ABC transporter Miro PF08477.8 EMG46450.1 - 0.00064 20.2 0.0 0.0014 19.1 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein Arch_ATPase PF01637.13 EMG46450.1 - 0.00071 19.3 0.2 0.0011 18.7 0.1 1.6 1 1 0 1 1 1 1 Archaeal ATPase DUF258 PF03193.11 EMG46450.1 - 0.00071 18.7 0.0 0.0011 18.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EMG46450.1 - 0.00081 19.5 0.1 0.0047 17.0 0.0 2.1 2 1 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 EMG46450.1 - 0.001 19.0 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EMG46450.1 - 0.0011 18.9 0.2 0.0031 17.4 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.1 EMG46450.1 - 0.0028 17.3 0.0 0.0065 16.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain KAP_NTPase PF07693.9 EMG46450.1 - 0.0032 16.4 0.2 0.0077 15.2 0.2 1.7 1 1 0 1 1 1 1 KAP family P-loop domain AAA_24 PF13479.1 EMG46450.1 - 0.0034 16.9 0.9 0.017 14.6 0.6 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EMG46450.1 - 0.0045 16.4 0.4 0.012 15.1 0.3 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.7 EMG46450.1 - 0.0046 16.6 0.0 0.0088 15.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 EMG46450.1 - 0.0059 16.7 0.5 0.017 15.3 0.3 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EMG46450.1 - 0.0067 16.0 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EMG46450.1 - 0.0075 15.0 0.0 0.01 14.5 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 EMG46450.1 - 0.0093 15.4 0.4 0.016 14.6 0.2 1.6 1 1 0 1 1 1 1 AAA-like domain T2SE PF00437.15 EMG46450.1 - 0.01 14.7 0.1 0.018 13.9 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.13 EMG46450.1 - 0.013 14.9 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 EMG46450.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 NTPase DUF2075 PF09848.4 EMG46450.1 - 0.02 13.9 0.0 0.024 13.6 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EMG46450.1 - 0.055 12.8 0.1 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.9 EMG46450.1 - 0.063 13.1 0.1 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) MobB PF03205.9 EMG46450.1 - 0.073 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EMG46450.1 - 0.076 12.7 0.0 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.14 EMG46450.1 - 0.091 12.2 0.0 0.22 10.9 0.0 1.6 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 EMG46450.1 - 0.11 12.7 3.7 0.22 11.8 2.6 1.8 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EMG46450.1 - 0.17 11.8 1.6 0.29 11.0 1.0 1.8 1 1 0 1 1 1 0 AAA domain HIG_1_N PF04588.8 EMG46451.1 - 3.7e-20 71.4 1.0 5.6e-20 70.8 0.7 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF4485 PF14846.1 EMG46451.1 - 0.17 11.6 1.5 0.25 11.0 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) ChAPs PF09295.5 EMG46453.1 - 2.7e-172 572.9 0.7 4.6e-172 572.2 0.5 1.4 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 EMG46453.1 - 4.6e-06 26.1 0.0 6.1e-05 22.5 0.0 2.6 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.1 EMG46453.1 - 0.00012 22.2 0.1 0.012 15.8 0.0 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMG46453.1 - 0.00059 20.4 0.0 0.0089 16.6 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMG46453.1 - 0.0025 17.4 0.1 2.3 8.1 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMG46453.1 - 0.015 15.1 0.1 21 5.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMG46453.1 - 0.054 14.1 0.0 18 6.3 0.0 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat PPR PF01535.15 EMG46453.1 - 0.074 13.0 0.0 0.25 11.3 0.0 2.0 1 0 0 1 1 1 0 PPR repeat TFIID-31kDa PF02291.10 EMG46454.1 - 8.5e-46 154.9 0.2 1.5e-45 154.1 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DUF1929 PF09118.6 EMG46454.1 - 0.81 9.8 5.1 0.5 10.4 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1929) Menin PF05053.8 EMG46454.1 - 1.2 7.1 4.7 1.7 6.7 3.3 1.2 1 0 0 1 1 1 0 Menin TPK_catalytic PF04263.11 EMG46455.1 - 3.9e-21 74.9 0.0 8.2e-20 70.6 0.0 2.1 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EMG46455.1 - 9.9e-08 31.5 0.0 1.8e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Ham1p_like PF01725.11 EMG46456.1 - 5.2e-52 175.9 0.0 5.9e-52 175.7 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DUF3602 PF12223.3 EMG46457.1 - 1.1e-28 99.4 16.9 2.7e-13 50.1 0.0 4.1 1 1 3 4 4 4 4 Protein of unknown function (DUF3602) Dehydrin PF00257.14 EMG46457.1 - 0.012 15.9 0.4 0.023 15.0 0.3 1.6 1 1 0 1 1 1 0 Dehydrin DUF1190 PF06693.6 EMG46457.1 - 0.025 14.6 2.5 2.3 8.2 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1190) BRF1 PF07741.8 EMG46458.1 - 0.54 10.5 6.4 4.5 7.5 3.8 2.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Mitofilin PF09731.4 EMG46459.1 - 1.4 7.5 7.3 1.7 7.2 5.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Hydrolase_6 PF13344.1 EMG46460.1 - 8.3e-27 93.0 0.0 2.2e-26 91.7 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMG46460.1 - 2.8e-05 24.4 0.0 0.28 11.3 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMG46460.1 - 3.2e-05 24.4 0.0 0.00035 21.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMG46460.1 - 0.00017 21.2 0.0 0.00043 19.9 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like DUF885 PF05960.6 EMG46460.1 - 0.093 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Xpo1 PF08389.7 EMG46462.1 - 1.6e-27 96.2 4.5 1.6e-27 96.2 3.1 4.3 5 0 0 5 5 5 1 Exportin 1-like protein MRP-L20 PF12824.2 EMG46464.1 - 1.7e-28 99.6 7.8 3.5e-28 98.6 5.3 1.7 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 LSM PF01423.17 EMG46464.1 - 5.7e-19 67.4 1.1 6.9e-19 67.1 0.2 1.6 2 0 0 2 2 2 1 LSM domain HTH_32 PF13565.1 EMG46464.1 - 0.45 11.3 3.5 1.1 10.1 0.3 2.4 1 1 1 2 2 2 0 Homeodomain-like domain UPRTase PF14681.1 EMG46465.1 - 3.6e-76 254.9 0.0 4.6e-76 254.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EMG46465.1 - 0.0045 16.7 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 EMG46465.1 - 0.065 12.9 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Actin PF00022.14 EMG46466.1 - 2e-134 447.9 0.0 2.3e-134 447.7 0.0 1.0 1 0 0 1 1 1 1 Actin Phosphodiest PF01663.17 EMG46466.1 - 0.04 13.2 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase EF-hand_6 PF13405.1 EMG46467.1 - 0.016 15.0 0.0 0.087 12.7 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.1 EMG46467.1 - 0.048 13.2 0.0 0.15 11.6 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair GRIM-19 PF06212.7 EMG46467.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.3 1 1 0 1 1 1 0 GRIM-19 protein POTRA_2 PF08479.6 EMG46467.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 POTRA domain, ShlB-type RNA_pol_Rpb6 PF01192.17 EMG46468.1 - 1.1e-22 79.4 1.1 1.9e-22 78.7 0.2 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb6 TilS_C PF11734.3 EMG46468.1 - 0.13 11.5 0.0 0.28 10.4 0.0 1.6 1 0 0 1 1 1 0 TilS substrate C-terminal domain Peptidase_M16 PF00675.15 EMG46469.1 - 4.4e-15 55.7 0.1 6.6e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EMG46469.1 - 6.1e-09 35.8 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Zn_clus PF00172.13 EMG46470.1 - 6.2e-07 29.2 11.3 1.3e-06 28.2 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain POTRA_1 PF08478.5 EMG46471.1 - 0.06 13.3 0.7 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 POTRA domain, FtsQ-type Zn_clus PF00172.13 EMG46471.1 - 1.8 8.5 5.1 2.1 8.3 0.7 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3994 PF13159.1 EMG46471.1 - 4.7 7.5 13.4 3 8.1 2.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3994) Zn_clus PF00172.13 EMG46472.1 - 6.1e-08 32.4 11.4 1.6e-07 31.0 7.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3446 PF11928.3 EMG46472.1 - 0.0096 16.1 2.7 0.023 14.8 1.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3446) GN3L_Grn1 PF08701.6 EMG46472.1 - 0.025 14.4 1.1 2.8 7.9 0.1 2.5 2 0 0 2 2 2 0 GNL3L/Grn1 putative GTPase Fungal_trans PF04082.13 EMG46473.1 - 9.2e-08 31.2 0.3 1.7e-07 30.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SLX9 PF15341.1 EMG46475.1 - 0.00015 22.1 0.0 0.0016 18.8 0.0 2.6 3 1 0 3 3 3 1 Ribosome biogenesis protein SLX9 DUF3015 PF11220.3 EMG46475.1 - 0.12 11.9 0.1 3.6 7.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3015) Cyclin_N PF00134.18 EMG46476.1 - 2.9e-19 68.8 1.4 3.4e-19 68.6 0.2 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.6 EMG46476.1 - 1.1e-13 51.8 0.2 1.1e-13 51.8 0.1 2.0 2 0 0 2 2 2 1 Cyclin PRP1_N PF06424.7 EMG46478.1 - 0.014 15.6 2.0 0.014 15.6 1.4 3.3 3 2 0 3 3 3 0 PRP1 splicing factor, N-terminal Med14 PF08638.6 EMG46479.1 - 6e-65 218.1 1.8 6e-65 218.1 1.2 3.2 4 0 0 4 4 4 1 Mediator complex subunit MED14 ROS_MUCR PF05443.6 EMG46479.1 - 0.097 12.4 0.2 0.29 10.8 0.1 1.9 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein Pkinase PF00069.20 EMG46480.1 - 3.5e-47 160.7 0.0 6.2e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG46480.1 - 2.7e-22 79.0 0.0 1.5e-21 76.6 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EMG46480.1 - 0.025 14.3 0.1 0.4 10.3 0.0 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EMG46480.1 - 0.089 11.7 0.1 0.34 9.8 0.0 1.8 2 0 0 2 2 2 0 Kinase-like PMSI1 PF15322.1 EMG46480.1 - 0.83 8.6 4.2 0.73 8.8 0.2 2.4 2 0 0 2 2 2 0 Protein missing in infertile sperm 1, putative WD40 PF00400.27 EMG46481.1 - 4.4e-06 26.3 0.3 0.00025 20.7 0.0 3.4 4 0 0 4 4 4 1 WD domain, G-beta repeat Phage_T4_Gp30_7 PF06919.6 EMG46481.1 - 0.0074 16.2 0.0 0.039 13.9 0.0 2.1 2 0 0 2 2 2 1 Phage Gp30.7 protein IKI3 PF04762.7 EMG46481.1 - 0.028 12.2 0.0 0.41 8.4 0.0 2.2 1 1 0 1 1 1 0 IKI3 family SET PF00856.23 EMG46482.1 - 9.5e-13 48.7 1.0 9.5e-13 48.7 0.7 2.3 2 1 0 2 2 2 1 SET domain TRP PF06011.7 EMG46483.1 - 4.6e-100 335.2 11.7 1.2e-99 333.8 8.2 1.6 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EMG46483.1 - 0.0015 18.6 3.3 0.018 15.0 1.7 2.5 2 0 0 2 2 2 1 ML-like domain GST_C PF00043.20 EMG46484.1 - 1.7e-09 37.5 0.1 1.7e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMG46484.1 - 2.1e-08 34.2 0.0 1e-07 32.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain EF1G PF00647.14 EMG46484.1 - 9.3e-08 31.7 0.1 2.6e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C_3 PF14497.1 EMG46484.1 - 1.1e-06 29.0 0.2 2.5e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMG46484.1 - 1.7e-06 27.7 0.0 3.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMG46484.1 - 0.00019 21.5 0.0 0.00057 20.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Lip_prot_lig_C PF10437.4 EMG46484.1 - 0.068 12.8 0.1 0.21 11.3 0.0 1.8 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus Sec16_C PF12931.2 EMG46485.1 - 2e-66 224.6 0.0 4e-66 223.6 0.0 1.5 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 EMG46485.1 - 3.1e-14 52.9 0.1 3.1e-14 52.9 0.0 2.8 3 0 0 3 3 3 1 Vesicle coat trafficking protein Sec16 mid-region PRANC PF09372.5 EMG46486.1 - 0.042 13.8 5.2 0.98 9.4 0.2 3.8 4 0 0 4 4 4 0 PRANC domain LRR_7 PF13504.1 EMG46486.1 - 0.05 13.7 1.5 1.5e+02 3.2 0.0 5.4 6 0 0 6 6 6 0 Leucine rich repeat FNIP PF05725.7 EMG46486.1 - 0.34 10.8 9.0 6.2 6.8 0.2 5.2 5 1 0 5 5 5 0 FNIP Repeat LRR_1 PF00560.28 EMG46486.1 - 1.1 9.5 9.3 3.3 8.1 0.0 5.6 7 1 0 7 7 7 0 Leucine Rich Repeat Zn_clus PF00172.13 EMG46487.1 - 0.00027 20.7 2.1 0.00027 20.7 1.4 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CwfJ_C_1 PF04677.10 EMG46487.1 - 0.067 12.8 0.0 0.067 12.8 0.0 2.4 3 0 0 3 3 3 0 Protein similar to CwfJ C-terminus 1 DUF3269 PF11673.3 EMG46487.1 - 0.26 11.7 1.5 2.4 8.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3269) TFIIA PF03153.8 EMG46487.1 - 0.92 9.3 10.7 1.2 8.9 7.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.11 EMG46488.1 - 5e-30 104.4 29.5 7e-30 103.9 20.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ribosomal_S7 PF00177.16 EMG46489.1 - 2.9e-38 130.7 3.4 2.9e-38 130.7 2.4 1.4 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e Lyase_1 PF00206.15 EMG46489.1 - 0.062 12.4 0.1 0.088 11.9 0.1 1.4 1 1 0 1 1 1 0 Lyase MFS_1 PF07690.11 EMG46490.1 - 8e-19 67.5 42.4 8e-19 67.5 29.4 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG46490.1 - 5.7e-10 38.3 5.6 5.7e-10 38.3 3.9 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter MLANA PF14991.1 EMG46490.1 - 1.1 9.3 3.4 3.1 7.8 0.1 2.8 3 0 0 3 3 3 0 Protein melan-A MFS_1 PF07690.11 EMG46491.1 - 2.6e-24 85.6 65.3 1e-18 67.2 27.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG46491.1 - 3.6e-06 25.8 11.8 3.6e-06 25.8 8.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMG46492.1 - 1.3e-20 73.4 45.7 1.3e-20 73.4 31.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily AAA PF00004.24 EMG46493.1 - 2.9e-43 147.2 0.0 5e-43 146.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EMG46493.1 - 5.3e-29 99.9 0.1 3.8e-28 97.1 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EMG46493.1 - 6.4e-23 80.4 2.2 2.1e-22 78.7 1.2 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_5 PF07728.9 EMG46493.1 - 2.9e-06 27.0 0.1 2.6e-05 23.9 0.0 2.6 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EMG46493.1 - 3.7e-06 27.7 0.1 3.4e-05 24.6 0.0 2.5 2 1 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 EMG46493.1 - 4.5e-06 26.8 1.0 0.0091 16.1 0.0 4.1 5 0 0 5 5 4 1 RNA helicase IstB_IS21 PF01695.12 EMG46493.1 - 9.6e-06 25.1 0.0 3.9e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.1 EMG46493.1 - 2.6e-05 24.3 0.1 0.0017 18.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMG46493.1 - 3.4e-05 23.7 0.0 0.00011 22.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EMG46493.1 - 3.5e-05 22.8 0.0 0.00022 20.2 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 EMG46493.1 - 4.2e-05 22.7 0.0 6.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EMG46493.1 - 7.8e-05 22.7 0.0 0.001 19.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EMG46493.1 - 0.00035 20.0 0.1 0.088 12.1 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 EMG46493.1 - 0.00048 20.0 0.0 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EMG46493.1 - 0.00048 18.9 0.0 0.00085 18.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 EMG46493.1 - 0.00097 19.0 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 EMG46493.1 - 0.0056 15.8 0.1 0.25 10.3 0.0 2.5 1 1 1 2 2 2 1 Zeta toxin AAA_18 PF13238.1 EMG46493.1 - 0.0082 16.4 0.2 0.027 14.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.1 EMG46493.1 - 0.019 14.5 0.3 0.036 13.6 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.1 EMG46493.1 - 0.02 14.6 0.0 0.054 13.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 EMG46493.1 - 0.022 13.9 0.0 0.062 12.4 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EMG46493.1 - 0.028 13.6 0.0 0.077 12.2 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EMG46493.1 - 0.047 13.3 0.0 0.62 9.7 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Torsin PF06309.6 EMG46493.1 - 0.053 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Torsin ResIII PF04851.10 EMG46493.1 - 0.063 13.0 0.1 0.43 10.3 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 EMG46493.1 - 0.081 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KaiC PF06745.8 EMG46493.1 - 0.085 11.9 0.0 5.4 6.0 0.0 2.4 1 1 1 2 2 2 0 KaiC Sigma54_activat PF00158.21 EMG46493.1 - 0.09 12.2 0.0 0.22 10.9 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 EMG46493.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 EMG46493.1 - 0.13 11.9 0.0 0.42 10.2 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Sigma54_activ_2 PF14532.1 EMG46493.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 EMG46493.1 - 0.14 11.8 2.2 0.35 10.5 0.0 2.4 2 1 1 3 3 3 0 Archaeal ATPase AAA_21 PF13304.1 EMG46493.1 - 0.22 11.4 1.6 2.8 7.8 0.0 2.7 2 1 1 3 3 3 0 AAA domain DUF2414 PF10309.4 EMG46494.1 - 3.5e-26 90.6 0.3 6.6e-26 89.7 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) Sorting_nexin PF03700.8 EMG46494.1 - 1.3 9.0 10.0 0.63 10.1 0.3 2.8 2 1 1 3 3 3 0 Sorting nexin, N-terminal domain LSM PF01423.17 EMG46495.1 - 1.7e-17 62.7 0.6 3.3e-17 61.7 0.4 1.5 1 0 0 1 1 1 1 LSM domain Flocculin_t3 PF13928.1 EMG46497.1 - 0.12 12.5 1.2 0.12 12.5 0.8 2.8 3 0 0 3 3 3 0 Flocculin type 3 repeat DUF4349 PF14257.1 EMG46497.1 - 2.3 7.3 4.9 3.4 6.8 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) LRR19-TM PF15176.1 EMG46499.1 - 0.11 12.1 2.8 0.68 9.6 1.9 2.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain MIP-T3 PF10243.4 EMG46501.1 - 0.084 11.3 41.9 0.16 10.4 29.0 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Proteasome PF00227.21 EMG46502.1 - 2.1e-23 82.6 0.0 2.7e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Phytase PF02333.10 EMG46502.1 - 0.0054 15.4 0.3 0.0081 14.9 0.2 1.2 1 0 0 1 1 1 1 Phytase DPPIV_N PF00930.16 EMG46503.1 - 5.3e-92 308.1 5.5 7.6e-92 307.6 3.8 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EMG46503.1 - 1.9e-43 148.1 0.1 3.3e-43 147.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMG46503.1 - 6.2e-07 29.2 0.0 1.9e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family PD40 PF07676.7 EMG46503.1 - 0.00075 19.1 0.2 1.6 8.5 0.0 3.0 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Abhydrolase_6 PF12697.2 EMG46503.1 - 0.0031 17.4 0.0 0.035 13.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EMG46503.1 - 0.016 14.5 0.0 0.095 11.9 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EMG46503.1 - 0.018 14.6 0.0 0.065 12.8 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EMG46503.1 - 0.02 14.3 0.1 0.05 13.0 0.0 1.6 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 EMG46503.1 - 0.038 12.5 0.0 0.07 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) NDUFA12 PF05071.11 EMG46504.1 - 3.1e-09 37.2 0.3 5e-09 36.5 0.1 1.4 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 WD40 PF00400.27 EMG46505.1 - 5.9e-10 38.6 5.8 0.0089 15.8 0.0 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat BBS2_N PF14781.1 EMG46505.1 - 0.025 14.1 2.1 0.22 11.1 0.0 3.3 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, N-terminal SART-1 PF03343.8 EMG46506.1 - 9.2e-81 272.0 77.2 8.8e-43 146.5 40.1 3.8 2 1 1 3 3 3 3 SART-1 family DUF4445 PF14574.1 EMG46506.1 - 0.21 9.7 0.9 0.39 8.9 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4445) E1-E2_ATPase PF00122.15 EMG46507.1 - 9e-45 152.4 1.8 1.9e-44 151.4 1.3 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EMG46507.1 - 1.2e-37 130.3 0.1 2.5e-37 129.3 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EMG46507.1 - 3.6e-13 49.4 1.2 1.2e-12 47.8 0.8 2.0 1 0 0 1 1 1 1 Heavy-metal-associated domain HAD PF12710.2 EMG46507.1 - 3.9e-13 50.0 0.2 1.3e-12 48.3 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMG46507.1 - 7.2e-08 32.3 6.6 3.2e-06 26.9 0.4 3.7 3 1 1 4 4 4 2 haloacid dehalogenase-like hydrolase Daxx PF03344.10 EMG46508.1 - 0.1 11.0 12.8 0.14 10.5 8.9 1.2 1 0 0 1 1 1 0 Daxx Family EBV-NA3 PF05009.7 EMG46508.1 - 0.76 8.9 2.8 8.7 5.5 0.0 2.2 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Gti1_Pac2 PF09729.4 EMG46509.1 - 2.1e-41 141.6 1.4 3.5e-35 121.3 0.0 3.4 2 2 1 3 3 3 2 Gti1/Pac2 family Atx10homo_assoc PF09759.4 EMG46510.1 - 2.4e-35 120.3 1.1 5.7e-35 119.1 0.4 1.9 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Thr_synth_N PF14821.1 EMG46511.1 - 7.7e-30 102.7 0.0 3.4e-29 100.6 0.0 2.1 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 EMG46511.1 - 1.3e-18 67.3 0.0 2.1e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Mmp37 PF09139.6 EMG46512.1 - 1.5e-104 349.5 3.6 2e-104 349.2 2.5 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 DUF1882 PF08966.6 EMG46512.1 - 0.011 15.6 0.2 0.011 15.6 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1882) Pox_TAA1 PF03295.9 EMG46512.1 - 0.077 12.6 0.1 0.24 11.0 0.1 1.8 1 0 0 1 1 1 0 Poxvirus trans-activator protein A1 C-terminal Fungal_trans PF04082.13 EMG46513.1 - 1.6e-13 50.1 1.5 1.6e-13 50.1 1.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG46513.1 - 4.2e-10 39.3 12.7 9.6e-10 38.2 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2424 PF10340.4 EMG46514.1 - 3.9e-31 108.0 0.1 5.9e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 EMG46514.1 - 4.9e-15 55.6 0.0 6.9e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMG46514.1 - 0.0048 16.6 0.0 0.0068 16.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EMG46514.1 - 0.032 14.4 0.0 0.049 13.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_6 PF12697.2 EMG46514.1 - 0.091 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Per1 PF04080.8 EMG46515.1 - 1.9e-101 338.9 19.0 1.9e-101 338.9 13.2 2.0 2 0 0 2 2 2 1 Per1-like NUC202 PF08166.7 EMG46515.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 NUC202 domain Adap_comp_sub PF00928.16 EMG46517.1 - 4.3e-11 42.4 0.3 6.9e-11 41.7 0.2 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EMG46517.1 - 5.1e-09 35.9 0.3 9.9e-09 35.0 0.2 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PDEase_II PF02112.10 EMG46518.1 - 1.8e-106 355.8 5.1 2.4e-106 355.4 3.6 1.1 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EMG46518.1 - 2e-05 24.2 0.1 3.6e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain SAP30_Sin3_bdg PF13867.1 EMG46519.1 - 1.4e-15 56.8 0.0 1.5e-14 53.5 0.0 2.4 2 1 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Tombus_movement PF05318.7 EMG46519.1 - 1.9 9.1 5.9 10 6.8 0.7 2.2 2 0 0 2 2 2 0 Tombusvirus movement protein RPA_C PF08784.6 EMG46519.1 - 4.4 7.7 6.5 5.1 7.5 2.7 1.9 2 0 0 2 2 2 0 Replication protein A C terminal DUF4336 PF14234.1 EMG46521.1 - 0.0061 15.7 0.0 0.013 14.6 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4336) DUF4336 PF14234.1 EMG46522.1 - 0.0073 15.5 0.0 0.86 8.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) Lactamase_B PF00753.22 EMG46522.1 - 0.036 13.7 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily WG_beta_rep PF14903.1 EMG46522.1 - 0.63 10.3 3.8 4.3 7.7 2.6 2.3 1 1 0 1 1 1 0 WG containing repeat PhyH PF05721.8 EMG46523.1 - 3.3e-14 53.4 0.0 7.6e-14 52.2 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AraC_binding PF02311.14 EMG46523.1 - 0.027 14.1 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain 2OG-FeII_Oxy_3 PF13640.1 EMG46523.1 - 0.091 13.2 0.1 0.2 12.2 0.0 1.6 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Aldolase_II PF00596.16 EMG46524.1 - 1.8e-49 167.8 0.7 2.3e-49 167.5 0.5 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Rop PF01815.11 EMG46524.1 - 0.13 11.6 0.2 0.42 10.1 0.0 1.9 2 0 0 2 2 2 0 Rop protein WD40 PF00400.27 EMG46525.1 - 0.0027 17.5 0.6 0.0088 15.8 0.4 1.8 2 0 0 2 2 2 1 WD domain, G-beta repeat HIRA_B PF09453.5 EMG46525.1 - 0.023 14.2 0.9 0.055 13.0 0.6 1.6 1 0 0 1 1 1 0 HIRA B motif CUE PF02845.11 EMG46526.1 - 4.7e-12 45.1 0.1 7.8e-12 44.4 0.0 1.4 1 0 0 1 1 1 1 CUE domain Kei1 PF08552.6 EMG46526.1 - 0.033 13.8 0.4 0.047 13.3 0.3 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Sec3_C PF09763.4 EMG46526.1 - 0.041 12.0 1.0 0.052 11.6 0.7 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Macoilin PF09726.4 EMG46526.1 - 0.14 10.4 2.8 0.15 10.3 1.9 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF755 PF05501.6 EMG46526.1 - 6.3 6.8 18.2 18 5.4 12.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF755) MARVEL PF01284.18 EMG46527.1 - 6.8e-17 61.6 14.3 9e-17 61.2 9.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF3328 PF11807.3 EMG46527.1 - 0.14 11.8 0.2 0.24 11.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) MNSV_P7B PF06692.6 EMG46527.1 - 5 6.9 5.8 0.45 10.3 0.6 1.8 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein Thioredoxin PF00085.15 EMG46528.1 - 8.1e-24 83.3 0.3 2.1e-23 82.0 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EMG46528.1 - 2.6e-08 34.0 0.6 6.1e-08 32.8 0.3 1.7 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EMG46528.1 - 1e-07 31.9 0.4 3e-05 24.0 0.1 2.9 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_6 PF13848.1 EMG46528.1 - 8.2e-05 22.4 0.1 0.00088 19.1 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like domain ERp29_N PF07912.8 EMG46528.1 - 0.0019 18.1 0.4 0.0039 17.1 0.3 1.5 1 1 0 1 1 1 1 ERp29, N-terminal domain Thioredoxin_7 PF13899.1 EMG46528.1 - 0.0031 17.5 0.2 0.0079 16.1 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 EMG46528.1 - 0.0086 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.1 EMG46528.1 - 0.014 14.9 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin AhpC-TSA PF00578.16 EMG46528.1 - 0.027 14.1 0.1 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.5 EMG46528.1 - 0.12 11.8 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Redoxin FSH1 PF03959.8 EMG46529.1 - 1.6e-67 227.0 0.1 2.2e-67 226.6 0.1 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EMG46529.1 - 1.7e-07 31.0 0.0 3.1e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EMG46529.1 - 0.00034 20.1 0.4 0.0061 16.0 0.3 2.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EMG46529.1 - 0.00072 19.4 0.0 0.016 15.1 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF1836 PF08876.6 EMG46529.1 - 0.012 15.3 0.2 0.31 10.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1836) DUF4263 PF14082.1 EMG46529.1 - 0.069 13.1 1.3 0.21 11.4 0.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4263) DLH PF01738.13 EMG46530.1 - 4.5e-26 91.4 0.0 5.3e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMG46530.1 - 2.9e-07 30.3 0.0 3.8e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMG46530.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EMG46530.1 - 0.17 11.7 0.0 0.61 9.9 0.0 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family ANTH PF07651.11 EMG46531.1 - 0.068 11.8 2.4 2.2 6.8 0.1 2.0 1 1 1 2 2 2 0 ANTH domain CAT PF00302.13 EMG46531.1 - 0.09 12.3 4.0 1.7 8.1 0.1 2.8 1 1 2 3 3 3 0 Chloramphenicol acetyltransferase Inhibitor_I29 PF08246.7 EMG46531.1 - 1.2 9.4 6.7 0.12 12.7 0.6 2.2 2 1 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) Tup_N PF08581.5 EMG46531.1 - 1.9 8.7 8.3 0.36 11.0 1.9 2.5 3 0 0 3 3 3 0 Tup N-terminal KMP11 PF03037.11 EMG46531.1 - 3.7 8.2 8.1 7.4 7.2 3.4 2.8 1 1 1 2 2 2 0 Kinetoplastid membrane protein 11 HHH PF00633.18 EMG46532.1 - 0.0076 15.8 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Kdo PF06293.9 EMG46534.1 - 8.1e-07 28.3 0.0 3.4e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMG46534.1 - 1.3e-06 28.3 0.0 5.2e-05 23.0 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EMG46534.1 - 1.3e-06 27.7 0.0 1.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EMG46534.1 - 2.5e-05 23.6 0.0 5.5e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.12 EMG46534.1 - 0.00072 18.7 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1679 PF07914.6 EMG46534.1 - 0.0021 16.7 0.0 0.0026 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 EMG46534.1 - 0.0075 15.4 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase LisH PF08513.6 EMG46535.1 - 0.006 16.3 0.1 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 LisH SPRY PF00622.23 EMG46535.1 - 0.021 14.8 0.9 0.35 10.9 0.6 2.4 1 1 0 1 1 1 0 SPRY domain Abhydrolase_2 PF02230.11 EMG46536.1 - 7.3e-57 192.2 0.0 8.7e-57 192.0 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EMG46536.1 - 2.1e-09 37.2 0.0 3e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EMG46536.1 - 1.1e-08 34.7 0.0 4.1e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EMG46536.1 - 1.7e-06 28.1 0.0 0.00013 21.9 0.0 2.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 EMG46536.1 - 5.3e-05 22.6 0.0 7.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EMG46536.1 - 0.0015 18.1 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.17 EMG46536.1 - 0.0062 16.2 0.0 0.016 14.9 0.0 1.6 1 1 1 2 2 2 1 Cutinase Lipase_3 PF01764.20 EMG46536.1 - 0.029 13.9 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Amidohydro_5 PF13594.1 EMG46536.1 - 0.043 13.6 0.0 0.11 12.3 0.0 1.9 1 1 0 1 1 1 0 Amidohydrolase Abhydrolase_1 PF00561.15 EMG46536.1 - 0.044 13.3 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold LIP PF03583.9 EMG46536.1 - 0.075 12.2 0.0 0.19 10.8 0.0 1.6 2 0 0 2 2 2 0 Secretory lipase Peptidase_M20 PF01546.23 EMG46537.1 - 1.4e-30 106.2 0.0 2e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMG46537.1 - 5.6e-11 42.1 0.0 1.1e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EMG46537.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.5 1 1 0 1 1 1 0 Peptidase family M28 60KD_IMP PF02096.15 EMG46538.1 - 2.7e-19 69.6 1.9 3.5e-19 69.2 1.3 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Spt4 PF06093.8 EMG46539.1 - 8.4e-31 105.6 0.1 1e-30 105.4 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger RNHCP PF12647.2 EMG46539.1 - 0.072 12.9 0.3 0.096 12.5 0.2 1.2 1 0 0 1 1 1 0 RNHCP domain RNA_POL_M_15KD PF02150.11 EMG46539.1 - 0.1 12.3 1.2 2.3 7.9 0.5 2.2 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit AAA PF00004.24 EMG46540.1 - 2.3e-49 166.9 0.0 1.2e-42 145.2 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMG46540.1 - 1.8e-06 28.0 0.0 1.8e-05 24.7 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.9 EMG46540.1 - 4e-06 26.8 0.0 2.5e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EMG46540.1 - 1.2e-05 24.7 0.0 0.00012 21.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.1 EMG46540.1 - 1.6e-05 25.0 1.2 0.002 18.2 0.1 3.8 2 2 1 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.1 EMG46540.1 - 2e-05 24.6 0.0 0.3 11.1 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain Bromodomain PF00439.20 EMG46540.1 - 2.9e-05 23.8 1.1 8.4e-05 22.4 0.1 2.3 2 0 0 2 2 2 1 Bromodomain AAA_5 PF07728.9 EMG46540.1 - 0.00072 19.2 0.0 0.0033 17.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EMG46540.1 - 0.0027 17.1 0.0 1.1 8.7 0.0 3.3 3 0 0 3 3 3 1 Sigma-54 interaction domain Shugoshin_C PF07557.6 EMG46540.1 - 0.005 16.2 5.9 0.07 12.6 0.0 3.3 3 0 0 3 3 3 1 Shugoshin C terminus AAA_19 PF13245.1 EMG46540.1 - 0.0077 15.9 0.1 0.019 14.7 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EMG46540.1 - 0.0089 15.4 0.1 0.027 13.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMG46540.1 - 0.011 15.6 0.0 0.032 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMG46540.1 - 0.012 15.7 0.0 0.098 12.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.16 EMG46540.1 - 0.038 13.1 0.0 0.1 11.7 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EMG46540.1 - 0.066 14.0 0.0 0.066 14.0 0.0 4.9 3 2 1 5 5 4 0 AAA domain ABC_tran PF00005.22 EMG46540.1 - 0.096 12.9 0.0 0.096 12.9 0.0 3.0 2 1 0 2 2 1 0 ABC transporter IncA PF04156.9 EMG46541.1 - 0.67 9.5 6.3 2.7 7.5 0.4 2.4 2 1 0 2 2 2 0 IncA protein ACCA PF03255.9 EMG46541.1 - 8.9 5.8 8.0 3.2 7.2 1.1 2.8 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit HAD_2 PF13419.1 EMG46542.1 - 5.6e-27 95.0 0.7 8.6e-27 94.4 0.5 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase tRNA-synt_1g PF09334.6 EMG46543.1 - 2.2e-120 401.9 0.4 3.3e-120 401.3 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EMG46543.1 - 2.5e-23 81.9 1.2 4.8e-11 41.3 0.0 3.1 1 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EMG46543.1 - 3.2e-12 46.1 0.0 1.2e-06 27.9 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Yip1 PF04893.12 EMG46543.1 - 4.1e-10 39.4 9.3 6.3e-10 38.8 6.5 1.3 1 0 0 1 1 1 1 Yip1 domain Anticodon_1 PF08264.8 EMG46543.1 - 0.0029 17.3 0.1 0.0068 16.1 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA SRP54 PF00448.17 EMG46544.1 - 7.9e-49 165.7 2.3 5.1e-48 163.1 1.6 2.2 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain CbiA PF01656.18 EMG46544.1 - 5.5e-09 35.7 0.1 1.7e-08 34.1 0.1 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54_N PF02881.14 EMG46544.1 - 1.9e-06 27.8 0.9 4.3e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_22 PF13401.1 EMG46544.1 - 1.9e-05 24.7 1.2 0.00017 21.7 0.0 2.8 2 1 1 3 3 3 1 AAA domain ArgK PF03308.11 EMG46544.1 - 7.3e-05 21.6 0.1 0.0002 20.2 0.0 1.8 2 0 0 2 2 2 1 ArgK protein Zeta_toxin PF06414.7 EMG46544.1 - 0.00086 18.4 0.0 0.0025 16.9 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 EMG46544.1 - 0.0036 16.7 0.0 0.0088 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EMG46544.1 - 0.0043 15.9 1.4 0.016 14.1 0.1 2.1 1 1 1 2 2 2 1 NB-ARC domain AAA_10 PF12846.2 EMG46544.1 - 0.015 14.7 0.3 0.06 12.7 0.0 2.1 2 1 0 2 2 2 0 AAA-like domain AAA_14 PF13173.1 EMG46544.1 - 0.023 14.6 0.2 0.16 11.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain Rsc14 PF08586.5 EMG46544.1 - 0.036 14.5 0.1 0.036 14.5 0.1 2.6 3 0 0 3 3 3 0 RSC complex, Rsc14/Ldb7 subunit AAA_30 PF13604.1 EMG46544.1 - 0.063 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EMG46544.1 - 0.073 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 EMG46544.1 - 0.12 12.2 0.1 0.33 10.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain PS_Dcarbxylase PF02666.10 EMG46545.1 - 2e-54 183.9 0.0 3.1e-54 183.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EMG46545.1 - 8.9e-22 76.7 1.8 3.2e-12 46.1 0.1 2.6 2 0 0 2 2 2 2 C2 domain zf-C2H2 PF00096.21 EMG46546.1 - 5.3e-08 32.7 23.6 2.3e-06 27.6 0.5 3.7 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMG46546.1 - 6.3e-08 32.4 18.4 8.7e-05 22.5 0.1 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMG46546.1 - 3.8e-05 23.7 0.4 3.8e-05 23.7 0.3 5.4 5 1 0 5 5 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 EMG46546.1 - 0.00027 20.7 5.6 0.12 12.3 0.3 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger CpXC PF14353.1 EMG46546.1 - 0.00032 20.6 1.6 0.0093 15.9 0.2 2.5 2 1 0 2 2 2 1 CpXC protein zf-BED PF02892.10 EMG46546.1 - 0.0013 18.4 3.1 0.0013 18.4 2.2 3.5 2 1 1 3 3 3 1 BED zinc finger zf-C2H2_2 PF12756.2 EMG46546.1 - 0.012 15.7 8.6 3.5 7.7 0.2 3.3 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.5 EMG46546.1 - 0.017 15.0 5.2 0.84 9.6 0.3 3.3 3 0 0 3 3 3 0 Zinc ribbon domain DUF3505 PF12013.3 EMG46546.1 - 0.023 14.9 0.3 0.062 13.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) zf-C2H2_jaz PF12171.3 EMG46546.1 - 0.04 14.0 10.0 0.71 10.0 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-HIT PF04438.11 EMG46546.1 - 0.083 12.5 2.4 8.2 6.1 0.1 2.3 2 0 0 2 2 2 0 HIT zinc finger zinc_ribbon_5 PF13719.1 EMG46546.1 - 0.19 11.3 6.3 1.2 8.7 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EMG46546.1 - 0.2 11.3 6.2 1.3 8.8 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_3 PF13878.1 EMG46546.1 - 0.38 10.3 5.4 0.18 11.4 0.4 2.6 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO DUF629 PF04780.7 EMG46546.1 - 0.42 9.0 4.5 0.7 8.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF629) Ribosomal_L44 PF00935.14 EMG46546.1 - 0.59 10.1 7.1 5.2 7.1 0.1 3.3 3 0 0 3 3 3 0 Ribosomal protein L44 GATA PF00320.22 EMG46546.1 - 1.1 8.6 4.1 9.1 5.7 0.3 2.4 2 0 0 2 2 2 0 GATA zinc finger zf-Di19 PF05605.7 EMG46546.1 - 1.4 9.1 11.9 1.7 8.8 0.9 4.2 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding DNA_RNApol_7kD PF03604.8 EMG46546.1 - 2.3 7.7 6.3 8.5 5.9 0.0 3.2 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-Mss51 PF13824.1 EMG46546.1 - 3.9 7.4 9.7 15 5.5 1.3 3.8 2 2 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Prok-RING_1 PF14446.1 EMG46546.1 - 6.1 6.6 9.0 2.1 8.1 0.3 2.8 3 0 0 3 3 2 0 Prokaryotic RING finger family 1 Ribonuclease_T2 PF00445.13 EMG46547.1 - 8.2e-43 146.2 2.9 8.2e-43 146.2 2.0 1.6 2 0 0 2 2 2 1 Ribonuclease T2 family Fungal_trans_2 PF11951.3 EMG46548.1 - 3.2e-15 55.6 3.6 4.3e-15 55.1 2.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG46548.1 - 2.6e-08 33.6 13.0 5.9e-08 32.4 9.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Auxin_repressed PF05564.7 EMG46549.1 - 0.079 13.5 2.4 0.089 13.3 1.7 1.1 1 0 0 1 1 1 0 Dormancy/auxin associated protein IF4E PF01652.13 EMG46550.1 - 3.3e-35 121.0 0.2 6.2e-35 120.1 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Sugar_tr PF00083.19 EMG46551.1 - 3e-62 210.7 14.1 3.3e-62 210.5 9.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG46551.1 - 0.00036 19.3 10.1 0.00036 19.3 7.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMG46551.1 - 0.00036 19.0 18.8 0.00049 18.6 4.4 2.4 2 1 1 3 3 3 2 MFS/sugar transport protein EBP PF05241.7 EMG46551.1 - 0.004 16.1 0.7 0.0082 15.1 0.5 1.5 1 0 0 1 1 1 1 Emopamil binding protein 7TM_GPCR_Srv PF10323.4 EMG46551.1 - 0.042 12.9 4.9 0.45 9.5 1.1 2.5 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF4149 PF13664.1 EMG46551.1 - 0.24 11.4 4.6 0.31 11.1 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) UDPGP PF01704.13 EMG46552.1 - 5.4e-45 153.6 0.1 8.5e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Septin PF00735.13 EMG46553.1 - 3.7e-59 200.0 3.1 4.7e-59 199.7 2.1 1.1 1 0 0 1 1 1 1 Septin AAA_14 PF13173.1 EMG46553.1 - 0.068 13.0 0.2 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_32 PF13654.1 EMG46553.1 - 0.069 11.8 0.1 0.13 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain SLS PF14611.1 EMG46554.1 - 2.9e-25 88.9 4.5 5.7e-25 87.9 3.1 1.5 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator TLV_coat PF00429.14 EMG46555.1 - 0.01 14.3 0.0 0.012 14.1 0.0 1.1 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) UPF0546 PF10639.4 EMG46555.1 - 0.082 12.7 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 Transgly_assoc PF04226.8 EMG46555.1 - 0.12 12.4 0.7 0.18 11.8 0.5 1.3 1 0 0 1 1 1 0 Transglycosylase associated protein Mannosyl_trans3 PF11051.3 EMG46556.1 - 4e-73 246.0 1.3 6e-73 245.5 0.4 1.6 2 0 0 2 2 2 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 EMG46556.1 - 0.00013 21.4 0.4 0.00027 20.3 0.3 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 8 OKR_DC_1_N PF03709.10 EMG46556.1 - 0.012 15.6 0.0 0.28 11.2 0.0 2.3 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain Ribonuclease_T2 PF00445.13 EMG46557.1 - 2.1e-42 144.8 1.6 3.8e-42 144.0 1.1 1.4 1 0 0 1 1 1 1 Ribonuclease T2 family AdoHcyase PF05221.12 EMG46558.1 - 9e-139 460.9 0.0 1e-138 460.7 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EMG46558.1 - 1.4e-82 275.3 2.8 2.3e-82 274.6 1.9 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EMG46558.1 - 2.3e-08 33.3 0.1 9.4e-08 31.4 0.1 1.9 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EMG46558.1 - 0.0059 16.2 0.1 0.012 15.1 0.1 1.6 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TMEM107 PF14995.1 EMG46558.1 - 0.038 14.0 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein TrkA_N PF02254.13 EMG46558.1 - 0.045 13.7 0.1 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain IlvN PF07991.7 EMG46558.1 - 0.062 12.6 0.2 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain GATA PF00320.22 EMG46559.1 - 2e-15 55.8 3.0 7.6e-15 53.9 2.1 2.1 1 0 0 1 1 1 1 GATA zinc finger Cep57_CLD PF14073.1 EMG46559.1 - 0.084 12.6 1.7 0.2 11.4 1.2 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Sec63 PF02889.11 EMG46561.1 - 2.2e-138 460.7 1.1 3.2e-91 305.8 0.1 2.8 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EMG46561.1 - 1.8e-53 180.5 1.3 1.3e-27 96.3 0.6 3.8 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EMG46561.1 - 5.3e-19 68.7 1.5 3e-08 33.7 0.1 3.0 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EMG46561.1 - 3.6e-17 62.0 0.0 2.4e-07 30.4 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 EMG46561.1 - 2.1e-06 27.9 1.3 0.084 13.0 0.2 3.5 3 2 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EMG46561.1 - 7e-05 22.4 0.0 0.31 10.8 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain PhoH PF02562.11 EMG46561.1 - 0.00028 20.2 0.0 0.11 11.6 0.0 2.7 2 0 0 2 2 2 2 PhoH-like protein AAA PF00004.24 EMG46561.1 - 0.00053 20.1 5.1 0.21 11.8 0.0 4.0 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EMG46561.1 - 0.014 14.7 0.1 5.5 6.3 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein Alpha-amylase PF00128.19 EMG46562.1 - 2.5e-105 352.3 1.6 5.4e-105 351.2 1.1 1.5 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 EMG46562.1 - 5.8e-05 22.1 0.1 0.00022 20.2 0.0 1.9 2 0 0 2 2 2 1 glucanotransferase domain of human glycogen debranching enzyme Sugar_tr PF00083.19 EMG46563.1 - 2.4e-76 257.1 30.5 3e-76 256.8 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG46563.1 - 1.1e-14 53.8 27.5 1.5e-14 53.4 16.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMG46563.1 - 9.9e-05 20.8 7.4 9.9e-05 20.8 5.1 3.6 3 1 1 4 4 4 3 MFS/sugar transport protein DUF2361 PF10153.4 EMG46564.1 - 2e-39 134.3 15.8 2e-39 134.3 11.0 1.9 2 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) DUF573 PF04504.9 EMG46564.1 - 4.1 7.7 9.5 2.5 8.4 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function, DUF573 DEK_C PF08766.6 EMG46564.1 - 4.5 7.1 7.9 5.2 6.9 0.0 3.6 4 0 0 4 4 4 0 DEK C terminal domain Myb_DNA-bind_4 PF13837.1 EMG46564.1 - 5.5 7.2 7.5 27 4.9 0.3 2.7 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain TGS PF02824.16 EMG46565.1 - 1.7e-19 69.3 0.0 3.8e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EMG46565.1 - 1e-17 64.1 0.1 2.4e-17 62.9 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMG46565.1 - 5.3e-13 48.5 0.0 9.3e-13 47.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EMG46565.1 - 0.00018 21.9 0.0 0.00042 20.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EMG46565.1 - 0.00043 20.1 0.9 0.015 15.1 0.0 2.4 1 1 1 2 2 2 1 Dynamin family ArgK PF03308.11 EMG46565.1 - 0.053 12.3 1.9 1 8.0 0.0 2.9 2 1 1 3 3 3 0 ArgK protein AIG1 PF04548.11 EMG46565.1 - 0.096 11.7 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Dynamitin PF04912.9 EMG46566.1 - 4e-17 62.1 32.4 5.6e-16 58.3 14.8 2.2 1 1 1 2 2 2 2 Dynamitin UBN2 PF14223.1 EMG46566.1 - 0.048 13.4 0.5 0.048 13.4 0.4 3.9 2 1 0 2 2 2 0 gag-polypeptide of LTR copia-type rRNA_proc-arch PF13234.1 EMG46566.1 - 0.17 11.0 14.3 0.046 12.8 0.7 3.5 2 1 0 3 3 3 0 rRNA-processing arch domain Reo_sigmaC PF04582.7 EMG46566.1 - 0.18 10.9 13.3 0.45 9.6 0.4 2.7 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Cob_adeno_trans PF01923.13 EMG46566.1 - 0.64 9.7 8.8 0.45 10.2 0.4 3.2 2 1 0 3 3 3 0 Cobalamin adenosyltransferase DUF1664 PF07889.7 EMG46566.1 - 3.7 7.3 15.1 5.5 6.7 1.1 3.4 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) TFR_dimer PF04253.10 EMG46566.1 - 3.7 7.1 8.2 1 8.9 1.0 3.0 3 0 0 3 3 3 0 Transferrin receptor-like dimerisation domain HAUS6_N PF14661.1 EMG46566.1 - 7.5 5.8 9.8 0.49 9.7 0.7 2.6 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 6 N-terminus NYD-SP28 PF14772.1 EMG46566.1 - 9.7 6.3 13.2 2.3 8.3 1.4 3.3 2 1 1 3 3 3 0 Sperm tail Aldedh PF00171.17 EMG46567.1 - 1.8e-105 352.9 0.0 2.3e-105 352.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.1 EMG46567.1 - 0.063 12.9 0.4 0.17 11.5 0.3 1.7 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated UPF0449 PF15136.1 EMG46567.1 - 0.085 13.0 0.0 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DnaJ_CXXCXGXG PF00684.14 EMG46568.1 - 8.3e-06 25.7 13.4 0.076 13.0 0.8 3.4 3 1 0 3 3 3 3 DnaJ central domain Spt4 PF06093.8 EMG46568.1 - 0.0038 17.0 0.1 0.0038 17.0 0.1 3.1 3 0 0 3 3 3 1 Spt4/RpoE2 zinc finger Ribosomal_L32p PF01783.18 EMG46568.1 - 0.54 10.4 5.4 0.24 11.6 0.6 2.6 2 0 0 2 2 2 0 Ribosomal L32p protein family DUF2082 PF09855.4 EMG46568.1 - 2.5 8.0 9.0 0.64 9.8 1.0 2.6 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Cytochrom_c3_2 PF14537.1 EMG46568.1 - 5.7 7.3 10.6 5.8 7.3 5.2 2.5 2 1 0 2 2 2 0 Cytochrome c3 zf-UBR PF02207.15 EMG46568.1 - 6.7 6.5 13.8 62 3.4 2.7 2.4 1 1 1 2 2 2 0 Putative zinc finger in N-recognin (UBR box) HypA PF01155.14 EMG46568.1 - 7.9 6.2 11.9 4 7.1 1.0 3.1 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family DNA_pol_E_B PF04042.11 EMG46569.1 - 7.6e-37 126.6 0.0 1.3e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Peptidase_S74 PF13884.1 EMG46569.1 - 0.0054 16.8 0.1 0.021 14.9 0.0 2.0 2 0 0 2 2 2 1 Chaperone of endosialidase DEAD PF00270.24 EMG46570.1 - 1.5e-45 154.7 1.4 4.9e-45 153.0 0.1 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG46570.1 - 1.2e-21 76.3 0.0 2.4e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EMG46570.1 - 5.5e-18 64.2 0.1 1.1e-17 63.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_22 PF13401.1 EMG46570.1 - 0.038 14.1 2.3 0.37 10.9 0.5 3.1 3 1 0 3 3 3 0 AAA domain ResIII PF04851.10 EMG46570.1 - 0.18 11.6 3.2 0.25 11.1 0.2 2.7 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit Alpha-amylase PF00128.19 EMG46571.1 - 1.9e-104 349.4 2.2 1.9e-104 349.4 1.5 1.6 2 0 0 2 2 2 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 EMG46571.1 - 2.4e-05 23.4 0.1 0.00026 20.0 0.0 2.2 2 0 0 2 2 2 1 glucanotransferase domain of human glycogen debranching enzyme Sugar_tr PF00083.19 EMG46572.1 - 1.4e-08 33.7 1.1 1.9e-08 33.3 0.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG46572.1 - 0.0013 17.5 0.2 0.0013 17.5 0.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Aldo_ket_red PF00248.16 EMG46573.1 - 7.8e-57 192.2 0.0 9.4e-57 191.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TauD PF02668.11 EMG46574.1 - 3.3e-25 89.2 0.0 5.7e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EMG46574.1 - 7.1e-06 26.3 0.1 2.4e-05 24.6 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF971) tRNA-synt_1g PF09334.6 EMG46576.1 - 4.2e-149 496.4 0.8 5.5e-149 496.0 0.6 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) MetRS-N PF09635.5 EMG46576.1 - 2.3e-28 99.0 0.4 5.5e-28 97.8 0.2 1.7 1 0 0 1 1 1 1 MetRS-N binding domain tRNA-synt_1 PF00133.17 EMG46576.1 - 3.5e-07 28.6 0.1 0.00053 18.1 0.0 3.0 1 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EMG46576.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA Amidase PF01425.16 EMG46577.1 - 9.4e-87 291.6 0.0 1.1e-86 291.5 0.0 1.0 1 0 0 1 1 1 1 Amidase GTP_cyclohydroI PF01227.17 EMG46578.1 - 2.9e-77 257.9 0.3 3.7e-77 257.6 0.2 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EMG46578.1 - 3.3e-05 23.7 0.0 0.00011 22.0 0.0 1.8 2 0 0 2 2 2 1 QueF-like protein RNB PF00773.14 EMG46579.1 - 2.2e-62 211.2 3.9 4.4e-62 210.2 2.7 1.5 1 0 0 1 1 1 1 RNB domain OB_RNB PF08206.6 EMG46579.1 - 0.00093 18.6 0.1 0.89 9.1 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease B OB domain LLC1 PF14945.1 EMG46579.1 - 0.17 12.1 2.1 0.25 11.6 0.1 2.2 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein zf-H2C2_2 PF13465.1 EMG46580.1 - 1.8e-08 34.2 19.7 5.3e-05 23.2 2.1 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EMG46580.1 - 3.8e-07 30.0 14.2 0.0021 18.3 0.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMG46580.1 - 0.0001 22.3 12.8 0.011 16.0 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger DUF685 PF05085.7 EMG46580.1 - 0.16 10.9 1.5 0.25 10.3 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF685) RRM_1 PF00076.17 EMG46581.1 - 3.4e-06 26.5 0.7 0.0017 17.9 0.0 3.5 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG46581.1 - 4.2e-06 26.6 0.0 3.1e-05 23.8 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG46581.1 - 2.1e-05 24.2 0.1 9.1e-05 22.2 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.7 EMG46581.1 - 0.88 7.4 28.7 0.0089 14.0 14.6 1.5 2 0 0 2 2 2 0 Nop14-like family Rhabdo_ncap PF00945.13 EMG46581.1 - 7.5 5.0 12.8 0.19 10.2 0.2 2.2 2 0 0 2 2 2 0 Rhabdovirus nucleocapsid protein Hyphal_reg_CWP PF11765.3 EMG46583.1 - 1.6e-22 79.7 0.1 2.7e-22 79.0 0.1 1.4 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Pput2613-deam PF14427.1 EMG46583.1 - 0.0014 18.2 6.3 3 7.5 0.0 5.2 1 1 4 6 6 6 3 Pput_2613-like deaminase NUDIX_4 PF14815.1 EMG46584.1 - 0.11 11.8 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 NUDIX domain CPSF73-100_C PF11718.3 EMG46585.1 - 0.15 11.3 3.0 0.17 11.2 2.1 1.1 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term TP6A_N PF04406.9 EMG46586.1 - 1.1e-08 34.6 0.4 2.3e-08 33.5 0.3 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Pantoate_transf PF02548.10 EMG46587.1 - 2.9e-106 354.3 0.1 3.5e-106 354.1 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EMG46587.1 - 1.6e-07 30.7 0.0 5.8e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase TPR_11 PF13414.1 EMG46587.1 - 0.14 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 TPR repeat LRR_5 PF13306.1 EMG46588.1 - 0.0051 16.5 4.2 0.051 13.2 0.2 2.8 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) Glyoxalase PF00903.20 EMG46589.1 - 1.9e-31 108.7 0.5 2.7e-15 56.4 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EMG46589.1 - 9.8e-24 84.0 0.0 1.7e-10 41.4 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EMG46589.1 - 1.4e-08 34.7 0.0 0.0028 17.6 0.0 3.1 1 1 2 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.1 EMG46589.1 - 0.00034 20.2 0.0 0.48 10.1 0.0 2.9 2 1 0 2 2 2 2 CppA N-terminal Glyoxalase_3 PF13468.1 EMG46589.1 - 0.013 15.4 0.0 2.6 7.9 0.0 2.5 2 1 0 2 2 2 0 Glyoxalase-like domain PRT_C PF08372.5 EMG46589.1 - 0.054 13.0 0.0 3 7.3 0.0 2.2 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal DuffyBP_N PF12377.3 EMG46589.1 - 1.7 8.8 5.1 1.2 9.4 0.1 3.0 3 0 0 3 3 3 0 Duffy binding protein N terminal K1 PF02960.9 EMG46590.1 - 0.18 11.8 5.0 0.37 10.8 0.1 2.8 2 1 0 2 2 2 0 K1 glycoprotein ABC_tran PF00005.22 EMG46591.1 - 1.9e-44 151.3 5.3 2.4e-21 76.4 0.1 3.6 3 1 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 EMG46591.1 - 5e-21 74.3 7.2 5e-21 74.3 5.0 3.5 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.1 EMG46591.1 - 4e-19 69.6 14.1 8.9e-09 35.7 0.0 5.1 5 0 0 5 5 5 3 AAA domain SMC_N PF02463.14 EMG46591.1 - 1.2e-10 40.9 2.7 0.00023 20.4 0.2 3.9 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EMG46591.1 - 7.9e-08 33.1 3.4 0.00037 21.3 0.1 3.6 4 0 0 4 4 3 2 AAA domain Miro PF08477.8 EMG46591.1 - 3.2e-06 27.6 0.2 0.17 12.4 0.0 3.3 2 1 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EMG46591.1 - 3.8e-06 26.3 0.2 0.085 12.4 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EMG46591.1 - 5.9e-06 25.5 0.1 0.024 13.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EMG46591.1 - 6.3e-06 26.3 1.6 0.25 11.4 0.4 3.9 3 1 0 3 3 3 2 AAA domain AAA_28 PF13521.1 EMG46591.1 - 1.5e-05 25.0 2.4 0.088 12.7 0.1 3.3 3 0 0 3 3 3 2 AAA domain AAA PF00004.24 EMG46591.1 - 0.00011 22.4 0.1 0.58 10.3 0.1 3.7 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EMG46591.1 - 0.00011 22.1 0.0 0.11 12.5 0.0 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 EMG46591.1 - 0.00012 21.8 1.2 0.52 10.0 0.0 3.1 3 1 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EMG46591.1 - 0.0003 20.8 4.1 0.0016 18.4 0.0 3.1 4 0 0 4 4 2 1 AAA ATPase domain NACHT PF05729.7 EMG46591.1 - 0.0004 20.0 0.4 0.57 9.8 0.0 2.8 2 0 0 2 2 2 2 NACHT domain ATP-synt_ab PF00006.20 EMG46591.1 - 0.0015 18.0 0.0 0.078 12.4 0.0 3.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.1 EMG46591.1 - 0.002 18.0 2.1 1.6 8.6 0.0 3.4 4 0 0 4 4 3 1 AAA domain PduV-EutP PF10662.4 EMG46591.1 - 0.0023 17.3 0.1 2.2 7.7 0.0 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.1 EMG46591.1 - 0.0038 17.1 0.1 1.5 8.8 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EMG46591.1 - 0.004 16.6 1.2 2.2 7.6 0.1 3.1 3 1 0 3 3 3 1 AAA-like domain AAA_14 PF13173.1 EMG46591.1 - 0.0048 16.8 1.4 0.85 9.5 0.0 3.6 4 0 0 4 4 2 1 AAA domain AAA_25 PF13481.1 EMG46591.1 - 0.0061 15.9 0.0 3.2 7.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EMG46591.1 - 0.0072 16.4 0.2 7.1 6.8 0.0 3.0 3 0 0 3 3 2 0 RNA helicase Dynamin_N PF00350.18 EMG46591.1 - 0.0087 15.8 0.6 0.0087 15.8 0.4 3.8 3 1 1 4 4 4 1 Dynamin family AAA_18 PF13238.1 EMG46591.1 - 0.01 16.1 0.4 0.086 13.1 0.1 4.1 5 1 0 5 5 3 0 AAA domain AAA_23 PF13476.1 EMG46591.1 - 0.013 15.8 0.6 0.16 12.2 0.1 5.3 4 1 1 5 5 4 0 AAA domain ArgK PF03308.11 EMG46591.1 - 0.024 13.4 0.2 0.58 8.8 0.0 3.2 3 1 0 3 3 3 0 ArgK protein T2SE PF00437.15 EMG46591.1 - 0.028 13.3 0.0 0.34 9.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.14 EMG46591.1 - 0.06 12.7 1.4 8.1 5.8 0.0 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 EMG46591.1 - 0.098 12.0 2.1 14 5.0 0.1 3.8 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 EMG46591.1 - 0.12 12.1 0.4 3.8 7.3 0.0 3.0 3 0 0 3 3 3 0 Part of AAA domain UPF0184 PF03670.8 EMG46591.1 - 1.2 9.3 7.3 0.26 11.4 0.5 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Glutaredoxin PF00462.19 EMG46592.1 - 1.5e-16 60.1 0.0 2.2e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.1 EMG46592.1 - 0.00064 19.2 0.1 0.00075 19.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Inos-1-P_synth PF01658.12 EMG46592.1 - 0.001 18.8 0.2 0.21 11.4 0.0 2.0 2 0 0 2 2 2 2 Myo-inositol-1-phosphate synthase Thioredoxin_3 PF13192.1 EMG46592.1 - 0.001 18.8 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain DSBA PF01323.15 EMG46592.1 - 0.0078 15.7 0.1 0.78 9.2 0.0 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain DUF836 PF05768.9 EMG46592.1 - 0.017 15.3 0.0 0.023 14.9 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.1 EMG46592.1 - 0.075 13.0 0.3 6.8 6.6 0.1 2.2 1 1 1 2 2 2 0 Thioredoxin TraF PF13728.1 EMG46592.1 - 0.14 11.5 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Svf1 PF08622.5 EMG46593.1 - 2.2e-134 447.5 6.0 2.8e-134 447.2 4.1 1.1 1 0 0 1 1 1 1 Svf1-like DUF2340 PF10209.4 EMG46593.1 - 0.01 16.0 0.2 0.098 12.8 0.1 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2340) Aldedh PF00171.17 EMG46594.1 - 1.7e-69 234.3 0.0 2.1e-69 234.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMG46594.1 - 8.1e-05 21.5 0.0 0.00013 20.8 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Abhydrolase_2 PF02230.11 EMG46595.1 - 2.9e-06 26.8 0.0 0.0092 15.4 0.0 2.4 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EMG46595.1 - 3.1e-06 27.2 0.0 3.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMG46595.1 - 0.00086 19.0 0.0 0.0017 18.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EMG46595.1 - 0.011 15.2 0.0 0.029 13.8 0.0 2.0 1 1 0 1 1 1 0 Putative esterase WD40 PF00400.27 EMG46596.1 - 2.1e-08 33.7 2.1 1.5e-05 24.6 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EMG46596.1 - 0.02 13.6 0.3 0.25 10.1 0.1 2.3 1 1 1 2 2 2 0 Coatomer WD associated region Myc_N PF01056.13 EMG46596.1 - 1 8.4 10.6 0.77 8.8 6.0 1.6 1 1 0 1 1 1 0 Myc amino-terminal region FYDLN_acid PF09538.5 EMG46596.1 - 1.3 9.6 11.7 3 8.4 8.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) NOA36 PF06524.7 EMG46596.1 - 1.3 8.1 5.4 2.2 7.4 3.7 1.3 1 0 0 1 1 1 0 NOA36 protein UCH PF00443.24 EMG46597.1 - 3.2e-47 160.8 1.3 6.5e-47 159.8 0.9 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMG46597.1 - 5.1e-14 52.4 8.2 3.3e-13 49.7 5.7 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EMG46597.1 - 3.7e-07 29.4 0.8 1.3e-06 27.6 0.5 1.9 1 0 0 1 1 1 1 Ubiquitin family DUF1690 PF07956.6 EMG46598.1 - 7.4e-44 149.1 3.4 8.6e-44 148.9 2.4 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Romo1 PF10247.4 EMG46599.1 - 1.1e-28 99.2 9.1 1.4e-28 98.8 6.3 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Lactamase_B_2 PF12706.2 EMG46600.1 - 2.9e-30 105.2 0.0 4.1e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMG46600.1 - 1.2e-13 51.1 0.0 1.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Actin PF00022.14 EMG46601.1 - 6.1e-20 71.0 0.4 1.4e-13 50.0 0.0 3.9 3 1 0 3 3 3 2 Actin MreB_Mbl PF06723.8 EMG46601.1 - 0.00029 19.5 0.0 0.0018 16.9 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein Peptidase_C50 PF03568.12 EMG46602.1 - 1e-83 281.1 0.1 3.3e-83 279.4 0.0 2.0 1 0 0 1 1 1 1 Peptidase family C50 Ligase_CoA PF00549.14 EMG46602.1 - 6.1e-24 84.3 0.1 1.2e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase IGR PF09597.5 EMG46602.1 - 3e-22 78.2 0.5 3e-22 78.2 0.3 2.6 3 0 0 3 3 3 1 IGR protein motif Succ_CoA_lig PF13607.1 EMG46602.1 - 2.4e-05 23.9 0.0 7.2e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding PF02629.14 EMG46602.1 - 0.018 15.5 1.1 0.018 15.5 0.7 2.0 2 0 0 2 2 2 0 CoA binding domain ISN1 PF06437.6 EMG46603.1 - 3.4e-182 605.7 0.0 3.8e-182 605.5 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase CIA30 PF08547.7 EMG46604.1 - 9.4e-41 139.2 0.0 1.3e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.8 EMG46604.1 - 0.036 13.7 0.2 0.06 13.0 0.1 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) NNMT_PNMT_TEMT PF01234.12 EMG46604.1 - 0.14 11.1 0.1 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family adh_short PF00106.20 EMG46605.1 - 2.3e-13 50.3 0.7 5.6e-13 49.1 0.0 2.0 3 0 0 3 3 3 1 short chain dehydrogenase Epimerase PF01370.16 EMG46605.1 - 6.9e-06 25.6 0.0 9.5e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EMG46605.1 - 0.0011 18.7 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMG46605.1 - 0.0039 16.8 0.0 0.013 15.1 0.0 1.8 2 0 0 2 2 2 1 KR domain Orthopox_B11R PF07033.6 EMG46606.1 - 0.25 10.8 1.0 0.36 10.3 0.6 1.4 1 1 0 1 1 1 0 Orthopoxvirus B11R protein RNA_pol_Rpb2_6 PF00562.23 EMG46607.1 - 9.1e-128 426.2 0.0 1.4e-126 422.3 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EMG46607.1 - 1.4e-66 223.2 0.1 2.5e-66 222.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EMG46607.1 - 3.9e-48 163.3 0.0 8.4e-48 162.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EMG46607.1 - 2.6e-31 107.6 0.1 6e-31 106.5 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EMG46607.1 - 6.8e-26 89.8 0.1 1.4e-25 88.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 EMG46607.1 - 1.2e-22 79.5 0.6 3.5e-22 78.1 0.4 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 EMG46607.1 - 5.7e-22 77.2 0.1 1.2e-21 76.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 Ribosomal_L23 PF00276.15 EMG46608.1 - 4.4e-17 61.8 0.0 9.2e-17 60.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 7TMR-HDED PF07697.6 EMG46608.1 - 0.011 15.4 0.1 0.046 13.4 0.0 1.8 2 0 0 2 2 2 0 7TM-HD extracellular TB2_DP1_HVA22 PF03134.14 EMG46609.1 - 2.6e-10 39.8 5.3 5.8e-09 35.5 1.2 3.1 3 0 0 3 3 3 2 TB2/DP1, HVA22 family Ribosomal_L13 PF00572.13 EMG46610.1 - 3.2e-43 146.8 0.1 4.1e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 UBA PF00627.26 EMG46611.1 - 5.5e-07 29.2 0.1 1.4e-06 27.9 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain DUF2424 PF10340.4 EMG46611.1 - 0.0035 16.0 0.3 0.0082 14.8 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) DUF2229 PF09989.4 EMG46611.1 - 0.005 16.3 0.9 0.011 15.1 0.6 1.5 1 0 0 1 1 1 1 CoA enzyme activase uncharacterised domain (DUF2229) Vps5 PF09325.5 EMG46612.1 - 7.1e-09 35.2 8.5 1.6e-08 34.1 5.9 1.5 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EMG46612.1 - 0.00039 20.1 0.1 0.00039 20.1 0.1 2.4 2 1 0 2 2 2 1 PX domain Ovate PF04844.8 EMG46612.1 - 0.037 13.8 0.7 0.11 12.3 0.1 2.1 2 0 0 2 2 2 0 Transcriptional repressor, ovate RPW8 PF05659.6 EMG46612.1 - 0.16 11.4 3.0 0.45 10.0 2.1 1.7 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 PINIT PF14324.1 EMG46613.1 - 2.5e-16 60.0 0.6 7.1e-16 58.5 0.4 1.8 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EMG46613.1 - 0.00011 21.5 0.8 0.0003 20.2 0.6 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EMG46613.1 - 0.82 9.2 7.1 0.086 12.3 0.4 2.7 2 1 1 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit SHS2_Rpb7-N PF03876.12 EMG46614.1 - 4.3e-17 61.9 0.0 7.1e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EMG46614.1 - 2.3e-14 53.2 0.1 3.8e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 EMG46614.1 - 0.079 13.1 0.0 0.15 12.3 0.0 1.5 1 1 0 1 1 1 0 RNA polymerase III subunit Rpc25 Sod_Fe_C PF02777.13 EMG46616.1 - 1.8e-34 117.7 0.2 3.6e-34 116.7 0.2 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EMG46616.1 - 4.3e-29 100.6 1.2 7.5e-29 99.8 0.9 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HHH_2 PF12826.2 EMG46616.1 - 0.084 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif tRNA-synt_1d PF00750.14 EMG46617.1 - 5.5e-90 301.7 10.1 1.8e-88 296.7 7.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EMG46617.1 - 5.3e-31 107.0 0.6 1.3e-30 105.7 0.0 2.0 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EMG46617.1 - 0.004 17.6 0.0 0.004 17.6 0.0 2.5 3 0 0 3 3 3 1 Arginyl tRNA synthetase N terminal domain Fmp27_GFWDK PF10347.4 EMG46618.1 - 0.044 13.7 0.0 0.048 13.6 0.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Ribosomal_S21e PF01249.13 EMG46619.1 - 1.6e-39 133.7 0.1 1.8e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Ribosomal_S5 PF00333.15 EMG46620.1 - 2.5e-26 91.1 3.6 2.5e-26 91.1 2.5 1.8 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EMG46620.1 - 1.8e-22 78.3 0.2 3.1e-22 77.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain CoA_binding_3 PF13727.1 EMG46620.1 - 0.094 12.5 0.2 0.43 10.4 0.0 1.9 1 1 1 2 2 2 0 CoA-binding domain DUF806 PF05657.6 EMG46620.1 - 0.12 12.3 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF806) Apolipoprotein PF01442.13 EMG46621.1 - 0.029 13.8 3.3 0.041 13.4 2.3 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Mlp PF03304.8 EMG46621.1 - 0.033 14.2 2.0 0.047 13.6 1.4 1.4 1 0 0 1 1 1 0 Mlp lipoprotein family BPD_transp_2 PF02653.11 EMG46621.1 - 0.036 13.0 0.0 0.046 12.6 0.0 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component LemA PF04011.7 EMG46621.1 - 0.058 12.4 1.4 0.11 11.6 0.2 1.8 1 1 1 2 2 2 0 LemA family DUF2342 PF10103.4 EMG46621.1 - 0.073 12.0 0.8 0.087 11.7 0.6 1.0 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2342) HrpE PF06188.7 EMG46621.1 - 0.13 11.9 3.4 0.22 11.2 2.2 1.4 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E DUF883 PF05957.8 EMG46621.1 - 0.15 12.4 9.0 0.37 11.2 0.9 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.6 EMG46621.1 - 0.22 11.5 7.4 0.32 11.0 5.2 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) ATP-synt_B PF00430.13 EMG46621.1 - 0.36 10.6 10.1 0.14 11.9 5.2 1.7 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DUF3584 PF12128.3 EMG46621.1 - 0.58 7.4 7.0 0.7 7.1 4.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) tRNA_U5-meth_tr PF05958.6 EMG46622.1 - 6.9e-24 84.1 0.6 8.5e-23 80.6 0.4 2.2 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EMG46622.1 - 1e-12 47.8 0.4 2.4e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain TRAM PF01938.15 EMG46622.1 - 2.3e-07 30.4 0.0 7e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 TRAM domain Methyltransf_15 PF09445.5 EMG46622.1 - 5.6e-06 25.9 0.2 1.2e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 EMG46622.1 - 6.7e-06 26.6 0.0 1.5e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMG46622.1 - 2e-05 24.0 0.0 3.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EMG46622.1 - 7.5e-05 22.7 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EMG46622.1 - 9.2e-05 22.1 0.1 0.00022 20.8 0.0 1.7 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.8 EMG46622.1 - 0.00014 21.1 0.1 0.00025 20.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EMG46622.1 - 0.0009 18.3 0.5 0.003 16.6 0.1 1.9 1 1 0 2 2 2 1 Putative methyltransferase Methyltransf_11 PF08241.7 EMG46622.1 - 0.001 19.5 0.0 0.0025 18.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMG46622.1 - 0.0024 18.1 0.0 0.0051 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EMG46622.1 - 0.0095 15.5 0.1 0.023 14.2 0.0 1.7 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.13 EMG46622.1 - 0.028 13.5 0.0 0.059 12.4 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family GCR1_C PF12550.3 EMG46623.1 - 1.5e-25 88.8 2.2 3.2e-25 87.7 1.5 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Syntaxin-6_N PF09177.6 EMG46623.1 - 1.8 9.0 7.5 0.19 12.1 0.2 3.3 4 0 0 4 4 4 0 Syntaxin 6, N-terminal PAP2 PF01569.16 EMG46624.1 - 1.4e-15 57.0 3.1 4.9e-15 55.3 2.2 1.9 1 0 0 1 1 1 1 PAP2 superfamily DUF1614 PF07758.6 EMG46624.1 - 0.97 9.1 7.6 1.5 8.4 0.4 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1614) Ras PF00071.17 EMG46625.1 - 7.8e-45 152.1 0.0 1.3e-44 151.4 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMG46625.1 - 3.6e-19 69.4 0.0 8e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMG46625.1 - 5.6e-07 28.9 0.0 8.9e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMG46625.1 - 0.02 14.0 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SCP2 PF02036.12 EMG46626.1 - 4e-21 75.2 0.3 4.4e-21 75.0 0.2 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EMG46626.1 - 7.2e-05 22.7 0.1 9e-05 22.4 0.1 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal ABC1 PF03109.11 EMG46627.1 - 6e-31 106.8 0.0 1.5e-30 105.6 0.0 1.7 1 0 0 1 1 1 1 ABC1 family FUSC_2 PF13515.1 EMG46628.1 - 2.2e-31 108.4 7.5 2.2e-31 108.4 5.2 3.2 2 1 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EMG46628.1 - 3e-14 53.2 2.6 2.6e-11 43.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2421) FUSC PF04632.7 EMG46628.1 - 1.3e-08 33.7 0.0 5.1e-06 25.2 0.1 2.3 2 0 0 2 2 2 2 Fusaric acid resistance protein family DUF1759 PF03564.10 EMG46628.1 - 0.025 14.3 0.5 3 7.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) SprT-like PF10263.4 EMG46628.1 - 0.11 12.1 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 SprT-like family ATP_synt_H PF05493.8 EMG46628.1 - 2.8 8.0 9.8 0.53 10.3 2.3 3.2 2 1 0 2 2 2 0 ATP synthase subunit H zf-CCCH_2 PF14608.1 EMG46629.1 - 4.4e-10 39.1 69.0 2.5e-06 27.2 1.9 7.6 7 1 0 7 7 7 6 Zinc finger C-x8-C-x5-C-x3-H type TSA PF03249.8 EMG46629.1 - 1.2 7.6 7.8 1.7 7.0 5.4 1.1 1 0 0 1 1 1 0 Type specific antigen DUF2508 PF10704.4 EMG46629.1 - 9.1 6.5 7.3 1.6 8.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Glyco_transf_8 PF01501.15 EMG46630.1 - 1.8e-25 89.7 1.9 7.5e-21 74.5 0.1 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 8 Zip PF02535.17 EMG46630.1 - 0.035 13.1 12.2 0.056 12.4 8.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter dUTPase PF00692.14 EMG46631.1 - 6.9e-44 148.4 0.0 8.3e-44 148.1 0.0 1.1 1 0 0 1 1 1 1 dUTPase DEAD PF00270.24 EMG46633.1 - 4.8e-45 153.0 1.9 8e-45 152.3 0.6 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG46633.1 - 2.8e-28 97.5 0.2 2e-27 94.8 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMG46633.1 - 5.9e-06 26.2 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EMG46633.1 - 0.00052 19.7 1.4 0.0012 18.5 0.4 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EMG46633.1 - 0.00067 19.8 0.0 0.0016 18.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EMG46633.1 - 0.00079 19.0 0.1 0.0013 18.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.1 EMG46633.1 - 0.0034 16.5 0.0 0.0078 15.3 0.0 1.6 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.9 EMG46633.1 - 0.021 14.5 0.2 0.12 12.1 0.1 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain UvrD-helicase PF00580.16 EMG46633.1 - 0.03 13.6 0.7 0.043 13.0 0.5 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Helicase_C_2 PF13307.1 EMG46633.1 - 0.084 12.8 0.1 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 Helicase C-terminal domain LETM1 PF07766.8 EMG46634.1 - 2.5e-100 334.9 3.1 4.5e-100 334.1 2.2 1.4 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 EMG46634.1 - 0.00084 18.7 0.0 0.086 12.3 0.0 2.6 2 0 0 2 2 2 2 SAP domain DUF325 PF03804.8 EMG46634.1 - 0.085 12.5 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Viral domain of unknown function Septin PF00735.13 EMG46635.1 - 8.8e-92 307.0 3.9 4.4e-91 304.7 2.7 2.1 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EMG46635.1 - 5.5e-08 32.7 0.1 1.9e-07 31.0 0.1 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 EMG46635.1 - 7.9e-06 25.6 0.1 0.00051 19.7 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B IIGP PF05049.8 EMG46635.1 - 6.9e-05 21.8 0.3 0.0002 20.3 0.1 1.8 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) DUF258 PF03193.11 EMG46635.1 - 0.00013 21.2 0.7 0.00096 18.3 0.5 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EMG46635.1 - 0.00013 22.4 0.1 0.00072 20.0 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EMG46635.1 - 0.00018 20.9 2.3 0.00094 18.6 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EMG46635.1 - 0.0008 19.5 0.1 0.0032 17.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AIG1 PF04548.11 EMG46635.1 - 0.001 18.2 0.7 0.054 12.5 0.2 2.8 1 1 1 2 2 2 1 AIG1 family Dynamin_N PF00350.18 EMG46635.1 - 0.0013 18.5 1.0 0.0013 18.5 0.7 3.4 2 2 0 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.13 EMG46635.1 - 0.0042 16.5 1.7 0.0045 16.4 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family Pox_A32 PF04665.7 EMG46635.1 - 0.0058 15.9 1.8 0.0065 15.7 0.1 1.9 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_24 PF13479.1 EMG46635.1 - 0.0075 15.8 0.1 0.02 14.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMG46635.1 - 0.01 15.7 0.8 0.025 14.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Synaptobrevin PF00957.16 EMG46635.1 - 0.031 13.8 1.1 0.083 12.4 0.7 1.7 1 0 0 1 1 1 0 Synaptobrevin RNA_helicase PF00910.17 EMG46635.1 - 0.044 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Ras PF00071.17 EMG46635.1 - 0.05 12.9 0.6 0.35 10.2 0.1 2.4 1 1 1 2 2 2 0 Ras family AAA_16 PF13191.1 EMG46635.1 - 0.11 12.4 0.0 0.11 12.4 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 EMG46635.1 - 0.18 12.0 0.0 0.18 12.0 0.0 2.7 2 1 0 2 2 1 0 ABC transporter ATP_bind_1 PF03029.12 EMG46635.1 - 1.5 8.2 6.9 0.88 9.0 1.0 2.7 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein YjeF_N PF03853.10 EMG46636.1 - 1.3e-36 125.7 0.0 1.5e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Trypan_PARP PF05887.6 EMG46638.1 - 1.4 8.7 7.7 2.4 7.9 5.3 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PITH PF06201.8 EMG46640.1 - 4.2e-35 120.7 4.3 4.2e-35 120.7 3.0 1.5 2 0 0 2 2 2 1 PITH domain Thioredoxin PF00085.15 EMG46640.1 - 8.2e-23 80.0 0.1 2.1e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EMG46640.1 - 3.5e-09 36.6 0.7 5.3e-08 32.8 0.1 3.1 2 2 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EMG46640.1 - 9.2e-09 35.5 0.6 4.3e-08 33.3 0.0 2.4 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EMG46640.1 - 9.3e-09 34.9 0.1 2.8e-08 33.3 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EMG46640.1 - 4.3e-08 33.0 0.1 1.3e-07 31.5 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EMG46640.1 - 0.00036 20.2 0.0 0.00076 19.1 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.1 EMG46640.1 - 0.00079 19.1 0.2 0.0058 16.4 0.0 2.5 3 0 0 3 3 3 1 Thioredoxin domain Redoxin PF08534.5 EMG46640.1 - 0.0046 16.4 0.0 0.0092 15.5 0.0 1.5 1 0 0 1 1 1 1 Redoxin Glutaredoxin PF00462.19 EMG46640.1 - 0.023 14.6 0.0 0.057 13.4 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin TrbC_Ftype PF09673.5 EMG46640.1 - 0.065 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein KaiB PF07689.7 EMG46640.1 - 0.12 11.8 0.0 0.33 10.4 0.0 1.7 1 0 0 1 1 1 0 KaiB domain ArfGap PF01412.13 EMG46641.1 - 0.0047 16.7 0.2 0.017 14.9 0.0 2.0 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf HEAT_EZ PF13513.1 EMG46642.1 - 1.3e-23 82.8 14.5 2.3e-08 34.2 0.0 11.1 8 3 3 11 11 11 4 HEAT-like repeat HEAT PF02985.17 EMG46642.1 - 2e-20 70.9 15.2 7.6e-05 22.4 0.0 13.6 15 1 1 16 16 16 4 HEAT repeat HEAT_2 PF13646.1 EMG46642.1 - 6.4e-19 68.0 14.1 1.2e-08 35.0 0.0 9.1 3 1 4 7 7 7 5 HEAT repeats IBN_N PF03810.14 EMG46642.1 - 1.9e-11 43.6 3.5 5e-11 42.3 0.6 3.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.18 EMG46642.1 - 7.8e-07 28.6 16.0 0.00022 20.9 0.0 7.4 9 0 0 9 9 9 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EMG46642.1 - 4e-05 23.0 0.6 1.5 8.1 0.0 4.3 3 2 1 4 4 4 2 CLASP N terminal RICTOR_V PF14668.1 EMG46642.1 - 0.0037 17.1 0.1 0.2 11.6 0.0 3.4 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 TIP120 PF08623.5 EMG46642.1 - 0.024 14.2 2.1 0.18 11.3 0.0 3.1 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) HEAT_PBS PF03130.11 EMG46642.1 - 0.049 14.1 6.4 12 6.7 0.1 6.2 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat RIX1 PF08167.7 EMG46642.1 - 0.16 11.6 2.1 3.6 7.2 0.3 4.0 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis Glyco_hydro_72 PF03198.9 EMG46643.1 - 2.6e-128 427.4 3.0 3.4e-128 427.0 2.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EMG46643.1 - 0.001 19.5 1.1 0.0029 18.0 0.3 2.1 2 0 0 2 2 2 1 X8 domain PBP1_TM PF14812.1 EMG46643.1 - 0.092 13.0 2.4 0.2 12.0 1.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 EMG46643.1 - 1.4 8.6 5.2 19 4.9 3.6 2.1 2 0 0 2 2 2 0 FAM176 family KOW PF00467.24 EMG46644.1 - 0.00057 19.4 1.4 0.00078 19.0 0.1 1.8 2 0 0 2 2 2 1 KOW motif 6PF2K PF01591.13 EMG46645.1 - 2.2e-60 203.5 0.1 3.1e-60 203.0 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EMG46645.1 - 3.7e-19 69.3 0.0 9.9e-19 67.9 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.5 EMG46645.1 - 0.00015 21.0 0.0 0.00024 20.3 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 EMG46645.1 - 0.00045 21.0 0.1 0.0031 18.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMG46645.1 - 0.0065 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EMG46645.1 - 0.01 15.5 0.0 0.025 14.2 0.0 1.7 1 1 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.1 EMG46645.1 - 0.023 14.8 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMG46645.1 - 0.027 14.2 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 EMG46645.1 - 0.055 13.7 0.0 0.16 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EMG46645.1 - 0.08 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Gon7 PF08738.5 EMG46646.1 - 1.1e-31 108.9 2.7 1.1e-31 108.8 1.9 1.0 1 0 0 1 1 1 1 Gon7 family ATP12 PF07542.6 EMG46647.1 - 1e-32 112.6 0.0 1.8e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein SMK-1 PF04802.10 EMG46648.1 - 8.6e-56 188.5 9.4 8.6e-56 188.5 6.5 2.4 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 WH1 PF00568.18 EMG46648.1 - 0.028 14.1 0.0 0.079 12.6 0.0 1.7 1 0 0 1 1 1 0 WH1 domain adh_short_C2 PF13561.1 EMG46649.1 - 2.2e-25 89.8 0.1 2.8e-25 89.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMG46649.1 - 7.4e-23 81.2 1.8 1e-22 80.7 1.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMG46649.1 - 8.3e-08 32.0 0.4 1.3e-07 31.5 0.3 1.2 1 0 0 1 1 1 1 KR domain Glucan_synthase PF02364.10 EMG46650.1 - 0 1415.7 0.0 0 1415.7 0.0 2.3 3 0 0 3 3 3 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EMG46650.1 - 3.8e-38 130.0 0.1 3.8e-38 130.0 0.1 2.1 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF1751 PF08551.5 EMG46651.1 - 1.9e-27 95.4 3.6 1.9e-27 95.4 2.5 1.9 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EMG46651.1 - 0.18 11.8 12.3 0.051 13.6 6.4 1.6 2 0 0 2 2 2 0 Rhomboid family SHP PF03579.8 EMG46651.1 - 1.6 8.1 5.5 0.22 10.8 0.2 2.3 2 0 0 2 2 2 0 Small hydrophobic protein Glyco_transf_34 PF05637.7 EMG46652.1 - 1.9e-55 187.9 2.2 3.2e-55 187.2 1.5 1.4 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EMG46652.1 - 0.02 14.1 0.3 1.4 8.1 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF273 Lactamase_B_2 PF12706.2 EMG46653.1 - 6.4e-09 35.6 0.3 1.1e-08 34.8 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EMG46653.1 - 2.2e-05 24.2 0.6 0.0013 18.3 0.2 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Arf PF00025.16 EMG46654.1 - 1.1e-30 106.1 0.3 1.4e-30 105.8 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMG46654.1 - 2.7e-05 23.6 0.0 3.1e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMG46654.1 - 3.1e-05 23.2 0.1 4.2e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EMG46654.1 - 0.00049 19.5 0.0 0.00059 19.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EMG46654.1 - 0.0013 17.5 0.5 0.0017 17.1 0.3 1.4 1 1 0 1 1 1 1 G-protein alpha subunit cobW PF02492.14 EMG46654.1 - 0.041 13.3 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF1959 PF09218.5 EMG46654.1 - 0.054 13.2 0.1 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1959) Glyco_hydro_17 PF00332.13 EMG46656.1 - 1.5e-06 27.5 0.1 3e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 AA_permease PF00324.16 EMG46657.1 - 4.1e-78 262.8 47.0 4.9e-78 262.6 32.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG46657.1 - 2.2e-25 89.0 54.8 3e-25 88.6 38.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1640 PF07798.6 EMG46658.1 - 2.7e-55 187.1 20.5 2.9e-55 187.0 10.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) V-SNARE_C PF12352.3 EMG46658.1 - 1.5e-09 37.7 0.6 5.9e-09 35.8 0.4 2.1 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EMG46658.1 - 3e-05 23.6 0.1 3e-05 23.6 0.1 3.7 2 1 1 4 4 4 1 Sec20 Baculo_PEP_C PF04513.7 EMG46658.1 - 0.016 15.0 13.0 0.018 14.8 1.3 3.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sigma70_r4 PF04545.11 EMG46658.1 - 0.068 12.4 0.2 0.21 10.9 0.1 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 HalX PF08663.5 EMG46658.1 - 0.07 13.1 6.3 1 9.4 0.1 3.7 3 1 1 4 4 4 0 HalX domain HALZ PF02183.13 EMG46658.1 - 0.25 11.1 9.7 0.045 13.4 1.3 3.6 4 0 0 4 4 4 0 Homeobox associated leucine zipper FlaC_arch PF05377.6 EMG46658.1 - 0.5 10.3 7.4 7.6 6.5 0.1 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Uds1 PF15456.1 EMG46658.1 - 0.69 9.9 12.9 0.51 10.3 4.6 2.6 2 0 0 2 2 2 0 Up-regulated During Septation Mt_ATP-synt_D PF05873.7 EMG46658.1 - 6.9 6.2 8.1 4.3 6.9 1.4 2.5 1 1 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) AA_permease PF00324.16 EMG46659.1 - 1.3e-111 373.2 38.5 1.6e-111 373.0 26.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG46659.1 - 1.9e-33 115.6 40.9 3e-33 115.0 28.4 1.3 1 0 0 1 1 1 1 Amino acid permease eIF2A PF08662.6 EMG46660.1 - 4.1e-82 274.5 0.0 4.4e-80 267.9 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EMG46660.1 - 0.015 14.1 0.1 0.12 11.1 0.0 2.3 3 1 0 3 3 3 0 Coatomer WD associated region OTU PF02338.14 EMG46661.1 - 1.1e-13 51.7 0.0 2.1e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EMG46661.1 - 0.00021 20.7 0.0 0.0046 16.3 0.0 2.7 4 0 0 4 4 4 1 Peptidase C65 Otubain zf-C2H2_jaz PF12171.3 EMG46662.1 - 2.9e-08 33.6 2.6 5.9e-08 32.6 1.8 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding IPT PF01745.11 EMG46662.1 - 0.031 13.4 0.1 0.038 13.1 0.1 1.1 1 0 0 1 1 1 0 Isopentenyl transferase zf-C2H2_2 PF12756.2 EMG46662.1 - 0.057 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 EMG46662.1 - 0.49 10.7 3.6 6.4 7.2 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain OmpH PF03938.9 EMG46662.1 - 2 8.3 8.3 5.1 7.0 5.8 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Ribosomal_L16 PF00252.13 EMG46663.1 - 1.1e-32 112.6 0.1 1.4e-32 112.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF2855 PF11017.3 EMG46664.1 - 0.037 13.1 0.1 0.043 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) PMM PF03332.8 EMG46665.1 - 5.2e-115 382.5 1.1 5.9e-115 382.4 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EMG46665.1 - 3.2e-08 33.4 0.0 3e-07 30.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EMG46665.1 - 0.00012 21.4 0.0 0.058 12.6 0.0 2.0 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 EMG46665.1 - 0.096 12.8 0.0 0.16 12.0 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMG46665.1 - 0.15 12.4 0.0 0.25 11.6 0.0 1.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase RCC1 PF00415.13 EMG46666.1 - 1.1e-20 73.5 0.0 9e-06 25.8 0.0 6.1 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMG46666.1 - 3.7e-15 55.0 3.9 4.9e-06 26.0 0.2 5.5 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat YcxB PF14317.1 EMG46666.1 - 0.0042 16.2 0.7 0.042 13.0 0.1 3.0 4 0 0 4 4 4 1 YcxB-like protein CBM_X PF06204.6 EMG46666.1 - 0.019 14.4 0.0 3.3 7.2 0.0 2.7 2 0 0 2 2 2 0 Putative carbohydrate binding domain tRNA-synt_2d PF01409.15 EMG46667.1 - 6e-89 297.4 0.0 8.2e-89 297.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EMG46667.1 - 5.7e-07 29.2 0.0 1.2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 EMG46667.1 - 3.2e-05 22.8 0.1 0.0008 18.2 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_His PF13393.1 EMG46667.1 - 0.049 12.6 0.1 0.17 10.9 0.0 1.8 2 0 0 2 2 2 0 Histidyl-tRNA synthetase DUF1642 PF07852.6 EMG46667.1 - 0.064 13.5 1.1 0.097 13.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1642) DUF2150 PF09920.4 EMG46667.1 - 0.84 9.2 5.5 0.49 9.9 0.5 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) Cellulase PF00150.13 EMG46668.1 - 1.4e-14 53.9 14.2 5e-14 52.1 9.9 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Homoserine_dh PF00742.14 EMG46669.1 - 8.3e-54 181.9 0.0 1.1e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EMG46669.1 - 7.8e-20 71.4 0.0 1.3e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF3608 PF12257.3 EMG46670.1 - 3.8e-142 472.1 1.1 6e-142 471.5 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EMG46670.1 - 1.8e-25 88.4 0.2 4.3e-25 87.2 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) SNO PF01174.14 EMG46671.1 - 2.2e-65 219.8 0.0 1.3e-63 214.0 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EMG46671.1 - 2.2e-07 30.6 0.0 1.7e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain DUF4066 PF13278.1 EMG46671.1 - 0.0075 15.5 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Putative amidotransferase Peptidase_C26 PF07722.8 EMG46671.1 - 0.012 15.0 0.0 0.07 12.5 0.0 2.0 2 0 0 2 2 2 0 Peptidase C26 GATase PF00117.23 EMG46671.1 - 0.06 12.7 0.0 3.2 7.1 0.0 2.4 2 1 1 3 3 3 0 Glutamine amidotransferase class-I BPL_N PF09825.4 EMG46671.1 - 0.12 11.1 0.0 1.4 7.6 0.0 2.0 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal SOR_SNZ PF01680.12 EMG46672.1 - 6.5e-104 346.0 6.6 6.5e-104 346.0 4.6 1.5 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.9 EMG46672.1 - 6.6e-11 41.7 0.4 2.1e-08 33.5 0.0 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 EMG46672.1 - 0.00046 19.1 0.1 0.14 10.9 0.0 2.5 2 1 1 3 3 3 2 Dihydrouridine synthase (Dus) NanE PF04131.9 EMG46672.1 - 0.0013 17.7 0.4 0.089 11.7 0.0 2.5 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.16 EMG46672.1 - 0.0026 16.8 0.2 0.0096 14.9 0.0 2.0 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase His_biosynth PF00977.16 EMG46672.1 - 0.0038 16.5 0.0 0.035 13.3 0.0 2.3 2 0 0 2 2 2 1 Histidine biosynthesis protein FMN_dh PF01070.13 EMG46672.1 - 0.022 13.6 0.1 0.061 12.1 0.0 1.7 2 0 0 2 2 2 0 FMN-dependent dehydrogenase PcrB PF01884.12 EMG46672.1 - 0.03 13.5 0.0 0.072 12.3 0.0 1.6 1 0 0 1 1 1 0 PcrB family AA_permease_2 PF13520.1 EMG46673.1 - 3.1e-61 207.1 54.7 3.9e-61 206.8 37.9 1.0 1 0 0 1 1 1 1 Amino acid permease Got1 PF04178.7 EMG46675.1 - 0.086 12.9 0.3 0.095 12.8 0.2 1.1 1 0 0 1 1 1 0 Got1/Sft2-like family LicD PF04991.8 EMG46677.1 - 7.1e-22 78.5 1.3 7.1e-22 78.5 0.9 3.3 4 1 0 4 4 4 1 LicD family LicD PF04991.8 EMG46678.1 - 2e-41 142.3 3.4 2e-41 142.3 2.4 3.2 4 1 0 4 4 4 1 LicD family Mgm101p PF06420.7 EMG46679.1 - 8.3e-90 298.6 0.0 1.3e-89 298.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 MAS20 PF02064.10 EMG46681.1 - 2.1e-22 79.3 2.5 3.8e-21 75.2 1.7 2.0 1 1 0 1 1 1 1 MAS20 protein import receptor Rhabdo_ncap PF00945.13 EMG46681.1 - 0.084 11.4 0.8 0.1 11.1 0.5 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein SR-25 PF10500.4 EMG46681.1 - 1.3 8.3 8.2 1.8 7.9 5.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-H2C2_2 PF13465.1 EMG46682.1 - 2.8e-05 24.1 9.5 3.6e-05 23.8 3.0 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EMG46682.1 - 0.00032 20.8 9.4 0.00044 20.4 0.3 3.7 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMG46682.1 - 0.0083 16.3 0.4 0.0083 16.3 0.3 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger Imm16 PF15565.1 EMG46682.1 - 0.095 12.5 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Immunity protein 16 DUF3221 PF11518.3 EMG46682.1 - 0.63 9.7 6.4 2.3 7.9 0.5 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3221) ArsA_ATPase PF02374.10 EMG46683.1 - 4.2e-108 360.9 0.2 4.9e-108 360.7 0.2 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EMG46683.1 - 3.8e-10 39.5 0.0 5.6e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EMG46683.1 - 3.9e-05 23.6 0.1 0.00011 22.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EMG46683.1 - 0.00011 21.1 0.0 0.0004 19.3 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain Fer4_NifH PF00142.13 EMG46683.1 - 0.0063 15.7 0.1 0.015 14.5 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.1 EMG46683.1 - 0.02 14.3 0.1 0.035 13.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 EMG46683.1 - 0.022 14.2 0.1 0.11 11.8 0.1 2.2 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 EMG46683.1 - 0.028 13.5 0.0 0.055 12.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EMG46683.1 - 0.081 13.7 0.0 0.18 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Bromodomain PF00439.20 EMG46684.1 - 2.4e-31 107.4 1.9 3.1e-16 59.0 0.3 3.0 2 1 0 2 2 2 2 Bromodomain BAH PF01426.13 EMG46684.1 - 3.5e-18 65.4 0.1 4.3e-17 61.9 0.0 2.3 2 0 0 2 2 2 1 BAH domain SIR2 PF02146.12 EMG46685.1 - 5.4e-28 97.9 0.0 1e-27 97.0 0.0 1.4 1 1 0 1 1 1 1 Sir2 family HSP20 PF00011.16 EMG46687.1 - 0.034 13.9 0.1 0.1 12.4 0.0 1.7 1 1 0 1 1 1 0 Hsp20/alpha crystallin family Spc7_N PF15402.1 EMG46687.1 - 0.61 8.0 12.6 0.67 7.8 8.7 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF605 PF04652.11 EMG46687.1 - 0.85 8.9 19.9 1 8.7 13.8 1.2 1 0 0 1 1 1 0 Vta1 like CDC27 PF09507.5 EMG46687.1 - 0.89 8.7 19.4 1.2 8.2 13.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Mitofilin PF09731.4 EMG46687.1 - 0.9 8.1 7.8 1 7.9 5.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Suf PF05843.9 EMG46687.1 - 4.4 6.9 10.3 7.3 6.2 7.1 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DLH PF01738.13 EMG46688.1 - 2e-30 105.7 0.1 1.4e-29 102.9 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family WD40 PF00400.27 EMG46688.1 - 1.2e-26 91.5 1.1 3.7e-07 29.7 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Abhydrolase_5 PF12695.2 EMG46688.1 - 6.7e-08 32.4 0.0 2.7e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2305 PF10230.4 EMG46688.1 - 0.0018 17.7 0.0 0.004 16.6 0.0 1.5 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) BAAT_C PF08840.6 EMG46688.1 - 0.0026 17.5 0.0 0.18 11.4 0.0 2.3 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 EMG46688.1 - 0.014 14.6 0.0 0.032 13.4 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family PD40 PF07676.7 EMG46688.1 - 0.018 14.7 0.2 5.9 6.6 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Peptidase_S15 PF02129.13 EMG46688.1 - 0.052 12.9 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PQQ_2 PF13360.1 EMG46688.1 - 0.062 12.7 0.0 0.11 11.8 0.0 1.5 1 1 0 1 1 1 0 PQQ-like domain 4F5 PF04419.9 EMG46689.1 - 3.7e-08 33.9 16.3 3.7e-08 33.9 11.3 2.4 2 1 0 2 2 2 1 4F5 protein family AMP-binding PF00501.23 EMG46690.1 - 6.8e-71 238.8 0.0 9.4e-71 238.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EMG46690.1 - 1.5e-70 236.9 0.0 2.4e-70 236.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EMG46690.1 - 1.3e-14 54.2 0.0 5.8e-14 52.1 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.16 EMG46690.1 - 5e-12 45.7 0.0 9.3e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 EMG46690.1 - 4.5e-09 37.1 0.0 1.4e-08 35.5 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 EMG46690.1 - 1.7e-07 30.2 0.0 4.9e-07 28.7 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EMG46690.1 - 0.0043 15.9 0.0 0.0075 15.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EMG46690.1 - 0.046 12.9 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.1 EMG46690.1 - 0.12 12.3 0.0 0.67 9.9 0.0 2.2 1 1 0 1 1 1 0 NADH(P)-binding SNF2_N PF00176.18 EMG46691.1 - 1e-70 237.8 0.0 1.5e-70 237.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMG46691.1 - 9.4e-12 44.6 0.0 1.9e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EMG46691.1 - 1.6e-09 37.2 9.1 1.6e-09 37.2 6.3 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 EMG46691.1 - 5.4e-07 29.2 0.0 1.2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.1 EMG46691.1 - 1.7e-05 24.5 8.8 1.7e-05 24.5 6.1 2.1 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMG46691.1 - 3.5e-05 23.7 8.2 3.5e-05 23.7 5.7 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMG46691.1 - 0.00016 21.4 8.7 0.00016 21.4 6.0 2.2 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EMG46691.1 - 0.00073 19.1 7.8 0.00073 19.1 5.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DevR PF01905.11 EMG46691.1 - 0.0074 15.1 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 CRISPR-associated negative auto-regulator DevR/Csa2 zf-RING_6 PF14835.1 EMG46691.1 - 0.04 13.7 3.0 0.11 12.3 2.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EMG46691.1 - 0.044 13.5 3.8 0.13 12.0 2.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger DUF356 PF04009.7 EMG46691.1 - 0.069 13.2 0.0 0.25 11.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF356) Zn_Tnp_IS91 PF14319.1 EMG46691.1 - 0.17 11.4 13.6 0.55 9.7 2.1 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-rbx1 PF12678.2 EMG46691.1 - 1.4 9.0 15.6 0.019 15.0 3.1 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger Vma12 PF11712.3 EMG46692.1 - 0.056 13.1 3.3 0.062 13.0 0.0 2.4 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PDEase_I PF00233.14 EMG46693.1 - 1.8e-41 142.4 2.6 8e-37 127.2 0.4 3.0 2 1 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Synaptobrevin PF00957.16 EMG46694.1 - 1.5e-14 53.3 0.3 2.5e-14 52.6 0.2 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EMG46694.1 - 1.9e-13 49.7 0.0 3e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain SAM_2 PF07647.12 EMG46695.1 - 2.3e-07 30.5 0.1 4.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMG46695.1 - 0.0036 17.4 0.0 0.0089 16.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CHCH PF06747.8 EMG46696.1 - 1.1e-07 31.5 3.5 2.1e-07 30.7 2.4 1.5 1 0 0 1 1 1 1 CHCH domain DUF1926 PF09095.6 EMG46696.1 - 0.057 12.6 0.1 0.057 12.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1926) SIP1 PF04938.7 EMG46696.1 - 0.11 11.8 0.1 0.11 11.8 0.0 2.1 2 0 0 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Complex1_LYR_2 PF13233.1 EMG46696.1 - 0.14 12.6 3.1 0.12 12.9 0.9 1.7 2 0 0 2 2 2 0 Complex1_LYR-like RNase_H2-Ydr279 PF09468.5 EMG46696.1 - 0.88 8.7 9.9 0.13 11.4 3.2 1.9 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) Ras PF00071.17 EMG46697.1 - 1e-38 132.2 0.5 2.3e-38 131.1 0.3 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EMG46697.1 - 3.1e-15 56.7 0.0 5.2e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMG46697.1 - 2.6e-09 36.5 2.5 1.1e-08 34.4 0.6 2.5 1 1 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMG46697.1 - 5.6e-08 32.2 0.1 7.7e-08 31.7 0.1 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMG46697.1 - 4.8e-06 26.5 1.2 0.00034 20.5 0.1 2.2 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMG46697.1 - 2.6e-05 23.7 0.2 4e-05 23.1 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EMG46697.1 - 0.013 14.6 0.4 0.062 12.4 0.3 2.3 1 1 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EMG46697.1 - 0.017 14.5 0.1 0.093 12.1 0.0 2.2 2 1 1 3 3 3 0 IstB-like ATP binding protein AAA_22 PF13401.1 EMG46697.1 - 0.04 14.0 0.0 0.084 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EMG46697.1 - 0.058 12.9 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EMG46697.1 - 0.098 12.6 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 EMG46697.1 - 0.27 10.7 2.8 4.1 6.8 0.0 3.0 1 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation APG17 PF04108.7 EMG46698.1 - 1.3e-93 314.0 11.7 1.5e-93 313.8 8.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 RNA_polI_A14 PF08203.6 EMG46698.1 - 0.025 14.7 0.7 0.094 12.9 0.0 2.3 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Thioredoxin_8 PF13905.1 EMG46698.1 - 0.094 12.8 2.6 2.3 8.4 0.1 3.3 2 1 1 3 3 3 0 Thioredoxin-like CDC73 PF05179.9 EMG46699.1 - 3.7e-52 177.3 0.4 4.7e-52 177.0 0.3 1.1 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family DUF2220 PF09983.4 EMG46699.1 - 0.0019 17.4 0.0 0.0033 16.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria C-term(DUF2220) tRNA-synt_2b PF00587.20 EMG46700.1 - 7.7e-54 181.8 0.2 1.1e-53 181.3 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMG46700.1 - 8.5e-19 67.2 0.2 1.6e-18 66.3 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain INO80_Ies4 PF08193.6 EMG46701.1 - 1.3e-25 90.7 2.1 1.4e-24 87.3 0.5 2.0 1 1 1 2 2 2 2 INO80 complex subunit Ies4 DUF150 PF02576.12 EMG46701.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised BCR, YhbC family COG0779 MDM31_MDM32 PF08118.6 EMG46702.1 - 1.9e-279 927.2 10.4 2.2e-279 927.0 7.2 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins PSI_PsaF PF02507.10 EMG46702.1 - 0.016 14.7 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III THUMP PF02926.12 EMG46702.1 - 0.073 12.9 0.2 0.69 9.7 0.0 2.2 2 0 0 2 2 2 0 THUMP domain Aminotran_5 PF00266.14 EMG46703.1 - 4e-31 108.0 0.0 5.6e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EMG46703.1 - 1.3e-09 37.5 0.0 3.3e-09 36.1 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EMG46703.1 - 1.1e-06 27.2 0.0 1.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SLA_LP_auto_ag PF05889.8 EMG46703.1 - 0.00023 19.7 0.0 0.00058 18.4 0.0 1.6 2 0 0 2 2 2 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) DegT_DnrJ_EryC1 PF01041.12 EMG46703.1 - 0.0037 16.3 0.0 0.0065 15.5 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF4089 PF13318.1 EMG46703.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4089) 2-Hacid_dh_C PF02826.14 EMG46704.1 - 9.6e-52 174.7 0.0 1.6e-51 173.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMG46704.1 - 1.2e-12 47.4 0.0 2.9e-12 46.2 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.7 EMG46704.1 - 0.00012 21.5 0.0 0.00022 20.6 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EMG46704.1 - 0.0012 18.7 0.0 0.0036 17.1 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EMG46704.1 - 0.0018 18.4 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EMG46704.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 EMG46704.1 - 0.019 14.8 0.4 3.1 7.6 0.0 3.1 2 1 1 3 3 3 0 ThiF family AlaDh_PNT_C PF01262.16 EMG46704.1 - 0.03 13.8 0.1 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.16 EMG46704.1 - 0.075 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain G-patch PF01585.18 EMG46705.1 - 8.9e-15 54.2 3.0 2e-14 53.1 2.1 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EMG46705.1 - 1.7e-08 34.1 0.1 3.8e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 DExH-box splicing factor binding site Barwin PF00967.12 EMG46706.1 - 0.1 12.3 1.7 0.28 10.8 1.2 1.8 1 0 0 1 1 1 0 Barwin family 2-Hacid_dh_C PF02826.14 EMG46707.1 - 3.5e-50 169.6 0.0 4.8e-50 169.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMG46707.1 - 2.1e-09 36.9 0.0 2.7e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMG46707.1 - 1.1e-06 28.6 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EMG46707.1 - 6.6e-05 22.3 0.1 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EMG46707.1 - 0.00017 21.9 0.0 0.00049 20.4 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.16 EMG46707.1 - 0.0083 15.9 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EMG46707.1 - 0.091 12.4 1.3 2.6 7.7 0.1 2.7 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 EMG46707.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CRCB PF02537.10 EMG46708.1 - 4.3e-30 103.9 26.4 4e-21 75.0 5.6 2.7 3 0 0 3 3 3 2 CrcB-like protein Ribosomal_S9 PF00380.14 EMG46709.1 - 2e-39 134.5 0.7 2.3e-39 134.3 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF2419 PF10343.4 EMG46709.1 - 0.034 13.4 0.0 0.039 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2419) Ribosomal_L13e PF01294.13 EMG46710.1 - 1.3e-63 213.6 5.7 1.9e-63 213.1 4.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_60s PF00428.14 EMG46711.1 - 2.9e-23 82.0 15.9 3.5e-23 81.8 11.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein adh_short PF00106.20 EMG46711.1 - 0.019 14.8 0.3 0.023 14.5 0.2 1.1 1 0 0 1 1 1 0 short chain dehydrogenase MFS_1 PF07690.11 EMG46712.1 - 3e-36 124.8 7.5 3e-36 124.8 5.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG46712.1 - 2e-08 33.2 3.4 2e-08 33.2 2.4 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter Voldacs PF03517.8 EMG46713.1 - 1.1e-09 38.2 2.8 1.1e-09 38.2 2.0 3.2 1 1 2 3 3 3 1 Regulator of volume decrease after cellular swelling WGG PF10273.4 EMG46714.1 - 2.6e-28 97.9 0.3 4.9e-28 97.0 0.2 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Prothymosin PF03247.9 EMG46714.1 - 0.011 15.8 17.3 0.019 15.0 12.0 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family Vfa1 PF08432.5 EMG46714.1 - 0.013 15.5 3.7 0.02 14.8 2.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Radial_spoke PF04712.7 EMG46714.1 - 0.024 13.4 6.3 0.033 12.9 4.4 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein TLP-20 PF06088.6 EMG46714.1 - 0.039 13.6 1.9 0.052 13.2 1.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PGA2 PF07543.7 EMG46714.1 - 0.11 12.2 4.8 0.2 11.4 3.3 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 FAM176 PF14851.1 EMG46714.1 - 0.28 10.8 5.8 0.47 10.1 4.0 1.4 1 0 0 1 1 1 0 FAM176 family Ribosomal_60s PF00428.14 EMG46714.1 - 0.31 11.4 7.4 0.56 10.6 5.1 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF2457 PF10446.4 EMG46714.1 - 0.35 9.5 11.0 0.48 9.0 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Myc_N PF01056.13 EMG46714.1 - 0.98 8.5 9.9 1.5 7.9 6.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.7 EMG46714.1 - 1.5 8.0 5.9 1.8 7.7 4.1 1.1 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 EMG46714.1 - 1.9 8.0 13.3 3.3 7.2 9.2 1.4 1 0 0 1 1 1 0 Nucleoplasmin Hid1 PF12722.2 EMG46715.1 - 7.9e-216 718.7 31.8 1.5e-214 714.5 22.0 2.0 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein DUF2339 PF10101.4 EMG46715.1 - 0.14 10.3 0.7 0.21 9.8 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) FKBP_C PF00254.23 EMG46716.1 - 7.7e-28 96.3 2.2 9.1e-28 96.1 0.0 2.2 3 1 0 3 3 3 1 FKBP-type peptidyl-prolyl cis-trans isomerase Daxx PF03344.10 EMG46716.1 - 2 6.8 46.5 0.044 12.2 10.2 2.1 2 0 0 2 2 2 0 Daxx Family Nop14 PF04147.7 EMG46716.1 - 5.1 4.8 55.9 2.5 5.8 15.2 2.0 2 0 0 2 2 2 0 Nop14-like family Ribosomal_L6e PF01159.14 EMG46717.1 - 2.8e-39 133.7 2.3 4.6e-39 133.0 1.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e KOW PF00467.24 EMG46717.1 - 3.6 7.4 5.7 1.4 8.7 0.3 2.7 2 1 1 3 3 3 0 KOW motif C2 PF00168.25 EMG46718.1 - 8.6e-55 182.5 8.0 6e-19 67.6 0.1 5.7 5 0 0 5 5 5 5 C2 domain NT-C2 PF10358.4 EMG46718.1 - 4.5e-06 26.2 8.4 0.23 10.9 0.4 4.9 4 1 0 4 4 4 3 N-terminal C2 in EEIG1 and EHBP1 proteins Ribosomal_S3Ae PF01015.13 EMG46719.1 - 8.2e-81 270.0 5.4 9.7e-81 269.7 3.7 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 EMG46719.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region SpoVIF PF14069.1 EMG46719.1 - 0.21 11.3 1.7 9.7 6.0 0.4 2.5 1 1 0 2 2 2 0 Stage VI sporulation protein F AAA PF00004.24 EMG46720.1 - 5.4e-17 62.2 0.0 1.5e-16 60.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMG46720.1 - 6.4e-12 45.8 0.0 1.9e-10 41.0 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EMG46720.1 - 1.8e-06 27.8 0.0 8.6e-06 25.6 0.0 2.1 1 1 0 1 1 1 1 Archaeal ATPase BAH PF01426.13 EMG46720.1 - 2.1e-06 27.4 0.2 7.5e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 BAH domain AAA_22 PF13401.1 EMG46720.1 - 8.6e-06 25.9 0.0 2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMG46720.1 - 0.021 14.5 0.0 0.064 13.0 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EMG46720.1 - 0.031 13.9 0.0 0.13 11.9 0.0 1.9 1 1 0 1 1 1 0 NACHT domain HMG-CoA_red PF00368.13 EMG46721.1 - 3.7e-161 535.9 0.7 4.7e-161 535.5 0.5 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 EMG46721.1 - 4.4e-30 104.4 1.4 6.3e-30 103.9 0.2 1.9 2 0 0 2 2 2 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 EMG46721.1 - 3e-10 39.7 6.0 6.5e-10 38.6 4.1 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Cyt-b5 PF00173.23 EMG46723.1 - 7.4e-11 41.6 0.2 1.1e-10 41.1 0.2 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF684 PF05075.9 EMG46723.1 - 0.0068 15.0 0.9 0.01 14.4 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF684) DUF791 PF05631.9 EMG46723.1 - 0.071 11.7 0.0 0.092 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF791) Cys_Met_Meta_PP PF01053.15 EMG46724.1 - 6.3e-38 130.0 0.0 8.4e-38 129.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EMG46724.1 - 1.8e-05 23.9 0.0 4e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II PDE6_gamma PF04868.7 EMG46724.1 - 0.01 15.6 0.0 0.029 14.2 0.0 1.8 2 0 0 2 2 2 0 Retinal cGMP phosphodiesterase, gamma subunit DUF1035 PF06281.7 EMG46726.1 - 0.022 14.5 1.1 0.049 13.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1035) Pox_A_type_inc PF04508.7 EMG46726.1 - 2.5 8.1 6.1 6.5 6.8 0.0 3.6 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Carn_acyltransf PF00755.15 EMG46727.1 - 6.7e-169 562.7 4.5 5.8e-153 510.1 2.5 2.3 2 1 0 2 2 2 2 Choline/Carnitine o-acyltransferase DUF1708 PF08101.6 EMG46728.1 - 4.4e-145 483.6 9.3 1.6e-144 481.8 6.4 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) bZIP_1 PF00170.16 EMG46729.1 - 1.5e-08 34.4 1.8 3.3e-08 33.3 1.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.3 EMG46729.1 - 1.3e-05 25.6 0.2 1.3e-05 25.6 0.1 4.2 5 0 0 5 5 5 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.10 EMG46729.1 - 1.5e-05 24.6 3.2 3.2e-05 23.6 2.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMG46729.1 - 0.028 14.7 0.7 0.028 14.7 0.5 3.0 3 0 0 3 3 3 0 bZIP Maf transcription factor CDC45 PF02724.9 EMG46729.1 - 1.7 6.5 13.2 2.9 5.8 9.1 1.4 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_47 PF01532.15 EMG46730.1 - 8.8e-161 535.5 0.1 1e-160 535.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 G_glu_transpept PF01019.16 EMG46731.1 - 6.3e-135 450.5 0.0 7.7e-135 450.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Bul1_N PF04425.7 EMG46732.1 - 3.6e-107 358.6 8.0 5.9e-107 357.9 5.5 1.3 1 0 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.7 EMG46732.1 - 9.5e-20 70.9 8.0 9.5e-20 70.9 5.6 2.9 3 1 0 3 3 3 1 Bul1 C terminus Campylo_MOMP PF05538.6 EMG46732.1 - 0.091 11.1 0.0 0.17 10.2 0.0 1.3 1 0 0 1 1 1 0 Campylobacter major outer membrane protein Bul1_N PF04425.7 EMG46733.1 - 3.6e-118 394.8 6.0 3.6e-118 394.8 4.1 1.6 2 0 0 2 2 2 1 Bul1 N terminus Bul1_C PF04426.7 EMG46733.1 - 1.9e-19 69.9 5.2 1.9e-19 69.9 3.6 3.4 4 1 0 4 4 4 1 Bul1 C terminus Hid1 PF12722.2 EMG46734.1 - 3.6 5.1 16.5 5.1 4.6 11.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.4 EMG46734.1 - 4 5.5 17.3 0.2 9.8 8.5 1.4 2 0 0 2 2 2 0 Transmembrane protein PQ-loop PF04193.9 EMG46735.1 - 3.7e-22 77.6 13.3 3.3e-12 45.7 0.4 2.8 2 0 0 2 2 2 2 PQ loop repeat INCENP_ARK-bind PF03941.10 EMG46736.1 - 2.7e-05 23.9 0.0 2.7e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region TPR_11 PF13414.1 EMG46737.1 - 5.8e-17 61.1 3.4 1.8e-14 53.1 0.6 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EMG46737.1 - 2e-10 39.8 10.2 5.5e-05 22.5 0.9 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMG46737.1 - 4.6e-09 35.5 4.0 0.028 14.3 0.3 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 EMG46737.1 - 1.6e-07 31.3 2.5 3.5e-07 30.2 1.6 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EMG46737.1 - 5.3e-05 23.0 0.8 0.058 13.3 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.13 EMG46737.1 - 6e-05 22.8 3.9 0.012 15.4 0.3 3.2 3 1 1 4 4 4 2 MIT (microtubule interacting and transport) domain Pox_T4_N PF04491.7 EMG46737.1 - 0.058 13.2 3.4 0.52 10.1 0.0 2.8 3 0 0 3 3 3 0 Poxvirus T4 protein, N terminus AAA_21 PF13304.1 EMG46737.1 - 0.25 11.2 6.5 0.045 13.6 2.1 1.5 2 0 0 2 2 2 0 AAA domain Fis1_TPR_C PF14853.1 EMG46737.1 - 0.64 9.9 5.3 3.4 7.6 0.1 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat PS_Dcarbxylase PF02666.10 EMG46738.1 - 8.9e-76 253.6 0.0 2e-73 245.9 0.0 2.5 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Apc1 PF12859.2 EMG46739.1 - 6.6e-18 64.8 0.0 2.8e-17 62.8 0.0 2.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EMG46739.1 - 0.13 12.5 12.5 0.26 11.6 0.2 5.0 5 0 0 5 5 5 0 Proteasome/cyclosome repeat Snf7 PF03357.16 EMG46740.1 - 6.6e-42 142.7 19.5 6.6e-42 142.7 13.5 1.8 1 1 1 2 2 2 1 Snf7 DASH_Dad4 PF08650.5 EMG46740.1 - 0.73 9.7 4.7 2.3 8.1 0.2 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad4 DUF3186 PF11382.3 EMG46740.1 - 0.91 8.5 8.6 0.32 10.0 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3186) zf-ZPR1 PF03367.8 EMG46740.1 - 1.2 8.2 6.1 1.7 7.7 2.9 2.0 1 1 1 2 2 2 0 ZPR1 zinc-finger domain SRP54_N PF02881.14 EMG46740.1 - 2.5 8.2 7.8 2.2 8.4 0.1 3.5 2 1 2 4 4 4 0 SRP54-type protein, helical bundle domain CITED PF04487.7 EMG46740.1 - 3.8 7.6 6.2 6.9 6.8 3.4 2.3 1 1 0 1 1 1 0 CITED DUF3573 PF12097.3 EMG46740.1 - 4 5.9 10.6 3.4 6.1 5.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) Tnp_P_element PF12017.3 EMG46740.1 - 4.5 6.4 7.7 1.5 7.9 2.1 2.2 1 1 0 2 2 2 0 Transposase protein Enkurin PF13864.1 EMG46740.1 - 5.9 7.1 19.5 10 6.4 5.1 3.5 2 2 1 3 3 3 0 Calmodulin-binding Syntaxin PF00804.20 EMG46741.1 - 7.6e-19 67.7 2.9 7.6e-19 67.7 2.0 3.0 2 1 0 2 2 2 1 Syntaxin SNARE PF05739.14 EMG46741.1 - 1.1e-18 66.7 5.7 2.3e-18 65.6 1.9 2.6 2 0 0 2 2 2 1 SNARE domain Sed5p PF11416.3 EMG46741.1 - 4.9e-17 61.0 2.3 4.9e-17 61.0 1.6 2.2 3 0 0 3 3 3 1 Integral membrane protein Sed5p Syntaxin-18_N PF10496.4 EMG46741.1 - 0.0011 18.7 5.2 0.012 15.4 0.3 3.4 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus FlaC_arch PF05377.6 EMG46741.1 - 0.0029 17.4 5.0 0.0056 16.5 0.1 3.2 2 2 1 3 3 3 1 Flagella accessory protein C (FlaC) MCPsignal PF00015.16 EMG46741.1 - 0.0068 15.9 0.8 0.0068 15.9 0.5 2.2 3 0 0 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1938 PF09153.5 EMG46741.1 - 0.034 13.9 0.9 0.1 12.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1938) DUF1461 PF07314.6 EMG46741.1 - 0.066 12.9 2.7 1.7 8.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) Laminin_II PF06009.7 EMG46741.1 - 0.12 12.0 0.3 0.12 12.0 0.2 3.2 3 1 1 4 4 4 0 Laminin Domain II Vac_Fusion PF02346.11 EMG46741.1 - 0.26 10.7 1.9 1.1 8.7 0.0 2.7 3 0 0 3 3 3 0 Chordopoxvirus fusion protein DUF1664 PF07889.7 EMG46741.1 - 0.31 10.8 6.3 2.5 7.9 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) APG17 PF04108.7 EMG46741.1 - 1.2 7.8 10.1 0.17 10.6 0.8 2.2 2 0 0 2 2 2 0 Autophagy protein Apg17 NPV_P10 PF05531.7 EMG46741.1 - 1.5 9.1 10.9 8.4 6.7 0.5 3.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Fungal_trans_2 PF11951.3 EMG46742.1 - 4.3e-64 216.5 2.2 5.7e-64 216.0 1.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG46742.1 - 2.2e-08 33.8 13.9 4.5e-08 32.8 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arch_fla_DE PF04659.8 EMG46742.1 - 0.44 10.3 5.3 1.4 8.7 0.1 3.1 3 0 0 3 3 3 0 Archaeal flagella protein Metallophos PF00149.23 EMG46743.1 - 1.3e-11 44.2 11.0 1.4e-10 40.8 7.6 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Mob1_phocein PF03637.12 EMG46744.1 - 6.5e-70 234.3 1.3 9e-70 233.8 0.9 1.2 1 0 0 1 1 1 1 Mob1/phocein family ORC6 PF05460.8 EMG46744.1 - 0.0016 17.6 2.4 0.0016 17.6 1.7 1.6 2 0 0 2 2 2 1 Origin recognition complex subunit 6 (ORC6) TFIIF_alpha PF05793.7 EMG46744.1 - 1.1 7.5 8.2 1.5 7.1 5.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAD-oxidase_C PF02913.14 EMG46745.1 - 1.1e-44 152.6 0.0 1.4e-44 152.2 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EMG46745.1 - 2.1e-31 108.2 0.0 5e-31 107.0 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain RNA_pol PF00940.14 EMG46746.1 - 4.8e-162 539.0 1.5 4.8e-162 539.0 1.0 1.9 2 0 0 2 2 2 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EMG46746.1 - 3.5e-76 256.4 0.1 1.1e-75 254.8 0.0 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal RIC1 PF07064.8 EMG46747.1 - 9.1e-15 54.8 0.8 9.1e-15 54.8 0.5 1.8 2 0 0 2 2 2 1 RIC1 Complex1_LYR PF05347.10 EMG46748.1 - 1.4e-07 31.1 0.3 2.5e-07 30.3 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMG46748.1 - 4.3e-07 30.0 0.3 8.5e-07 29.0 0.2 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EMG46748.1 - 0.00014 22.2 1.7 0.00019 21.8 1.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Tubulin PF00091.20 EMG46749.1 - 7.1e-72 241.7 0.0 1.2e-71 241.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMG46749.1 - 2e-48 163.5 0.1 3.3e-48 162.8 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EMG46749.1 - 4.9e-05 23.3 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EMG46749.1 - 0.0028 17.1 0.0 0.0053 16.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Metallophos PF00149.23 EMG46750.1 - 1.6e-40 138.7 0.0 2.4e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase VHS PF00790.14 EMG46751.1 - 2.9e-21 75.5 0.1 6.8e-21 74.3 0.1 1.6 1 0 0 1 1 1 1 VHS domain FYVE PF01363.16 EMG46751.1 - 4.5e-19 68.1 3.1 8e-19 67.3 2.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 EMG46751.1 - 0.009 15.9 1.8 0.021 14.7 1.3 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger UIM PF02809.15 EMG46751.1 - 0.11 12.0 0.1 0.11 12.0 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin interaction motif OAD_gamma PF04277.8 EMG46751.1 - 0.28 11.5 1.0 0.96 9.8 0.0 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain zf-RING_2 PF13639.1 EMG46751.1 - 1.1 9.1 6.2 2.5 7.9 4.3 1.5 1 0 0 1 1 1 0 Ring finger domain Orn_Arg_deC_N PF02784.11 EMG46752.1 - 7.8e-69 231.6 0.0 1.1e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EMG46752.1 - 4.6e-30 103.7 0.6 1.1e-29 102.5 0.1 1.9 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DUF2098 PF09871.4 EMG46752.1 - 0.1 12.5 0.2 0.32 10.9 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) Cyclin_N PF00134.18 EMG46753.1 - 5.5e-20 71.2 0.0 1.4e-19 69.8 0.0 1.8 1 1 0 1 1 1 1 Cyclin, N-terminal domain Rot1 PF10681.4 EMG46754.1 - 3.6e-96 320.5 0.6 4.3e-96 320.3 0.4 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal zf-C2H2_4 PF13894.1 EMG46756.1 - 0.00025 21.1 0.7 0.00091 19.3 0.5 2.0 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EMG46756.1 - 0.0038 17.4 1.5 0.011 15.9 1.0 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type DUF4428 PF14471.1 EMG46756.1 - 0.01 15.5 0.2 0.031 14.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) zf-met PF12874.2 EMG46756.1 - 0.016 15.4 2.3 0.072 13.3 1.6 2.2 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-BED PF02892.10 EMG46756.1 - 0.04 13.6 0.4 0.11 12.2 0.3 1.7 1 0 0 1 1 1 0 BED zinc finger PRANC PF09372.5 EMG46757.1 - 0.098 12.6 2.4 0.21 11.5 0.1 2.6 2 1 0 2 2 2 0 PRANC domain LRR_8 PF13855.1 EMG46757.1 - 0.15 11.8 0.9 1.2 8.9 0.1 2.6 2 0 0 2 2 2 0 Leucine rich repeat LRR_8 PF13855.1 EMG46758.1 - 1e-08 34.7 12.2 0.0021 17.7 0.8 4.8 3 2 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 EMG46758.1 - 1.2e-07 31.1 18.6 5.4e-05 22.7 0.8 5.6 2 1 3 6 6 6 3 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EMG46758.1 - 0.01 15.8 15.0 2.6 8.6 0.3 6.7 8 0 0 8 8 8 0 Leucine rich repeat LRR_1 PF00560.28 EMG46758.1 - 0.02 14.8 19.7 1.7 8.9 0.8 6.8 7 2 0 7 7 7 0 Leucine Rich Repeat Pentapeptide_4 PF13599.1 EMG46758.1 - 0.11 12.3 1.3 0.44 10.3 0.4 2.3 2 1 0 2 2 2 0 Pentapeptide repeats (9 copies) LRR_2 PF07723.8 EMG46758.1 - 0.38 11.3 4.7 1.1 9.8 0.1 3.8 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.1 EMG46758.1 - 5.6 7.3 16.2 18 5.8 0.8 5.9 5 1 0 5 5 5 0 Leucine Rich repeat Miro PF08477.8 EMG46759.1 - 8.1e-36 123.1 0.1 7.6e-18 65.1 0.0 3.4 2 1 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 EMG46759.1 - 1e-28 98.4 0.2 2.4e-28 97.2 0.1 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_2 PF08356.7 EMG46759.1 - 1.5e-28 98.3 0.0 5.5e-28 96.5 0.0 2.0 2 0 0 2 2 1 1 EF hand associated Ras PF00071.17 EMG46759.1 - 2.8e-22 78.8 0.0 4.7e-11 42.3 0.0 3.4 3 0 0 3 3 3 3 Ras family MMR_HSR1 PF01926.18 EMG46759.1 - 4.7e-08 32.9 0.8 0.021 14.7 0.4 3.6 3 2 0 3 3 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.27 EMG46759.1 - 7.1e-07 28.0 6.9 0.0016 17.6 0.2 3.0 2 0 0 2 2 2 2 EF hand Dynamin_N PF00350.18 EMG46759.1 - 4.8e-06 26.4 1.3 0.0016 18.3 0.1 2.8 2 1 0 2 2 2 1 Dynamin family EF-hand_7 PF13499.1 EMG46759.1 - 6.1e-06 26.2 2.8 0.027 14.5 0.2 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EMG46759.1 - 2.8e-05 23.2 5.9 0.077 12.3 0.1 2.8 2 0 0 2 2 2 2 EF hand Arf PF00025.16 EMG46759.1 - 4.3e-05 22.8 0.0 0.0035 16.5 0.0 2.8 3 0 0 3 3 2 1 ADP-ribosylation factor family EF-hand_6 PF13405.1 EMG46759.1 - 0.00015 21.3 8.7 0.029 14.2 0.4 3.0 2 0 0 2 2 2 2 EF-hand domain MobB PF03205.9 EMG46759.1 - 0.0032 17.1 1.3 1.1 8.9 0.0 3.0 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B EF-hand_8 PF13833.1 EMG46759.1 - 0.0045 16.5 1.5 2.9 7.5 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair AAA_16 PF13191.1 EMG46759.1 - 0.0048 16.9 0.0 2.1 8.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EMG46759.1 - 0.0086 15.9 0.1 1.8 8.4 0.0 3.0 2 2 0 2 2 2 1 AAA domain Septin PF00735.13 EMG46759.1 - 0.013 14.5 1.7 0.21 10.5 1.0 2.5 2 1 0 2 2 2 0 Septin Glyco_hydro_65m PF03632.10 EMG46759.1 - 0.014 14.0 2.0 0.024 13.3 1.4 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain ABC_tran PF00005.22 EMG46759.1 - 0.017 15.4 0.0 0.59 10.4 0.1 2.4 2 0 0 2 2 2 0 ABC transporter EF-hand_4 PF12763.2 EMG46759.1 - 0.026 14.2 0.0 0.073 12.8 0.0 1.7 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand FeoB_N PF02421.13 EMG46759.1 - 0.036 13.3 0.1 11 5.2 0.0 3.1 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_29 PF13555.1 EMG46759.1 - 0.04 13.4 0.0 5.4 6.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EMG46759.1 - 0.041 13.5 0.0 4.5 6.8 0.0 2.7 2 1 0 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 EMG46759.1 - 0.066 13.5 3.9 0.26 11.5 0.1 3.0 3 1 0 3 3 3 0 AAA domain AAA_22 PF13401.1 EMG46759.1 - 0.067 13.3 0.0 13 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zip PF02535.17 EMG46759.1 - 0.1 11.5 6.6 0.18 10.7 4.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter FtsK_SpoIIIE PF01580.13 EMG46759.1 - 0.13 11.7 0.0 8 5.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 EMG46759.1 - 0.15 11.9 0.0 24 4.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain Macoilin PF09726.4 EMG46759.1 - 0.48 8.6 10.3 0.69 8.1 7.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Bul1_N PF04425.7 EMG46760.1 - 5.4e-93 311.9 5.5 1.2e-92 310.7 3.8 1.5 1 1 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.7 EMG46760.1 - 2.9e-18 66.0 17.8 4.4e-10 39.1 0.1 3.3 4 0 0 4 4 4 2 Bul1 C terminus ETC_C1_NDUFA4 PF04800.7 EMG46761.1 - 2.4e-28 97.9 0.4 3.3e-28 97.5 0.3 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region SWIB PF02201.13 EMG46762.1 - 1.4e-27 95.1 0.6 4.7e-27 93.4 0.1 2.0 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.6 EMG46762.1 - 1.8e-13 50.0 1.1 3e-13 49.3 0.1 1.8 2 0 0 2 2 2 1 DEK C terminal domain Lipase_GDSL PF00657.17 EMG46763.1 - 1.3e-22 80.7 0.1 1.8e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EMG46763.1 - 3.6e-21 76.0 0.0 4.4e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Imm1 PF14430.1 EMG46763.1 - 0.065 13.3 0.0 0.3 11.2 0.0 1.9 1 1 1 2 2 2 0 Immunity protein Imm1 RRS1 PF04939.7 EMG46764.1 - 1.3e-65 219.9 7.5 1.5e-65 219.7 5.2 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Sugar_tr PF00083.19 EMG46765.1 - 5.3e-76 256.0 23.3 6.2e-76 255.7 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG46765.1 - 2.8e-21 75.6 24.6 5e-19 68.2 5.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMG46765.1 - 7.6e-07 27.7 0.2 7.6e-07 27.7 0.1 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) BBP1_C PF15272.1 EMG46766.1 - 0.00014 21.4 23.4 0.00014 21.4 16.2 1.6 2 0 0 2 2 2 1 Spindle pole body component BBP1, C-terminal PKK PF12474.3 EMG46766.1 - 0.0069 16.1 9.1 0.0069 16.1 6.3 3.0 1 1 0 2 2 2 1 Polo kinase kinase Stm1_N PF09598.5 EMG46766.1 - 0.11 13.2 0.0 0.33 11.6 0.0 1.8 1 0 0 1 1 1 0 Stm1 Tox-REase-2 PF15646.1 EMG46766.1 - 0.14 11.9 5.7 0.15 11.9 0.7 2.4 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 2 DUF3347 PF11827.3 EMG46766.1 - 1.5 8.8 6.6 3 7.8 4.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) MADF_DNA_bdg PF10545.4 EMG46766.1 - 3.2 7.9 10.1 1 9.6 1.5 2.7 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Imm3 PF14425.1 EMG46766.1 - 4.9 7.1 11.3 6.5 6.7 6.8 2.0 1 1 0 1 1 1 0 Immunity protein Imm3 ERG2_Sigma1R PF04622.7 EMG46767.1 - 1.5e-81 272.8 0.4 1.7e-81 272.5 0.3 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein DDE_1 PF03184.14 EMG46768.1 - 2.3e-19 69.4 0.2 3.5e-19 68.8 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Alpha_E2_glycop PF00943.14 EMG46768.1 - 0.14 10.7 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein Metallophos PF00149.23 EMG46769.1 - 3.2e-07 29.9 14.7 3.7e-06 26.4 10.2 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DDE_1 PF03184.14 EMG46770.1 - 8.7e-27 93.6 0.0 3.2e-26 91.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EMG46770.1 - 0.019 14.7 0.0 0.043 13.5 0.0 1.7 1 0 0 1 1 1 0 DDE superfamily endonuclease bZIP_1 PF00170.16 EMG46770.1 - 0.75 9.7 3.1 2.3 8.2 2.2 1.8 1 0 0 1 1 1 0 bZIP transcription factor DUF4065 PF13274.1 EMG46770.1 - 1.1 10.0 9.2 0.062 14.0 0.6 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF4065) PCI PF01399.22 EMG46771.1 - 9.2e-07 29.1 8.9 9.2e-07 29.1 6.2 2.8 2 1 0 2 2 2 1 PCI domain DUF383 PF04063.9 EMG46771.1 - 0.069 12.6 2.9 1.4 8.4 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF383) ORC6 PF05460.8 EMG46772.1 - 3e-91 306.1 1.8 3.6e-91 305.9 1.2 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Herpes_UL87 PF03043.9 EMG46772.1 - 0.0097 14.3 0.5 0.013 13.9 0.4 1.1 1 0 0 1 1 1 1 Herpesvirus UL87 family Reticulon PF02453.12 EMG46772.1 - 0.018 14.6 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 Reticulon MatE PF01554.13 EMG46773.1 - 9.5e-50 168.3 29.8 1.2e-29 103.0 5.4 2.6 2 0 0 2 2 2 2 MatE Autophagy_N PF03986.8 EMG46775.1 - 1.5e-49 167.5 0.5 1.5e-49 167.5 0.3 2.0 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EMG46775.1 - 4.2e-22 78.0 0.1 8.9e-22 77.0 0.1 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EMG46775.1 - 3.4e-15 54.8 1.1 6.8e-15 53.8 0.7 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal DUF1799 PF08809.6 EMG46775.1 - 0.098 12.4 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Phage related hypothetical protein (DUF1799) DUF4140 PF13600.1 EMG46775.1 - 0.25 11.8 0.2 0.25 11.8 0.1 1.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) LCAT PF02450.10 EMG46776.1 - 2.6e-111 372.3 1.3 6.1e-111 371.1 0.9 1.6 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 EMG46776.1 - 0.016 14.9 0.0 0.044 13.5 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF1792 PF08759.6 EMG46776.1 - 0.041 13.4 0.1 0.15 11.6 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1792) Podoplanin PF05808.6 EMG46776.1 - 0.062 12.8 0.6 0.13 11.7 0.4 1.5 1 0 0 1 1 1 0 Podoplanin ESSS PF10183.4 EMG46776.1 - 0.07 13.5 0.1 0.25 11.7 0.0 1.9 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Zip PF02535.17 EMG46776.1 - 2 7.3 5.2 3.7 6.4 3.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter PDZ_1 PF12812.2 EMG46777.1 - 2.3e-49 165.2 0.1 6.9e-33 112.3 0.0 3.4 3 0 0 3 3 3 2 PDZ-like domain PDZ_2 PF13180.1 EMG46777.1 - 2.5e-15 56.1 1.2 3.6e-05 23.5 0.0 4.5 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.1 EMG46777.1 - 2.7e-14 53.2 0.0 3.8e-12 46.2 0.0 2.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ PF00595.19 EMG46777.1 - 3.2e-10 40.0 0.0 2.2e-06 27.7 0.0 3.0 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 EMG46777.1 - 9.9e-05 22.0 0.1 0.01 15.6 0.0 2.9 3 0 0 3 3 3 1 Tricorn protease PDZ domain Trypsin PF00089.21 EMG46777.1 - 0.00097 18.7 0.0 0.0028 17.2 0.0 1.7 1 0 0 1 1 1 1 Trypsin DUF31 PF01732.11 EMG46777.1 - 0.0031 16.9 0.1 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative peptidase (DUF31) Peptidase_S7 PF00949.16 EMG46777.1 - 0.0043 16.4 0.1 0.0097 15.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.4 EMG46777.1 - 0.014 13.8 1.2 0.17 10.2 0.1 2.1 2 0 0 2 2 2 0 Peptidase S46 Peptidase_S3 PF00944.14 EMG46777.1 - 0.017 14.5 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 Alphavirus core protein OmpH PF03938.9 EMG46778.1 - 0.0086 16.0 11.9 0.011 15.6 8.3 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Peptidase_M16 PF00675.15 EMG46778.1 - 0.016 14.9 2.7 0.02 14.6 1.9 1.1 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) Nefa_Nip30_N PF10187.4 EMG46778.1 - 0.26 11.4 21.3 0.081 13.1 8.3 2.1 1 1 1 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 APG6 PF04111.7 EMG46778.1 - 0.48 9.4 11.9 0.57 9.1 8.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Exonuc_VII_L PF02601.10 EMG46778.1 - 0.97 8.5 10.2 1.1 8.3 7.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TAF8_C PF10406.4 EMG46778.1 - 4.6 7.3 7.3 2.9 8.0 1.6 2.5 2 1 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term DUF4337 PF14235.1 EMG46778.1 - 7.8 6.3 12.2 11 5.8 8.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) N-SET PF11764.3 EMG46779.1 - 2.9e-49 167.1 1.1 2.9e-49 167.1 0.8 3.6 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 EMG46779.1 - 2.4e-29 100.4 1.1 4.8e-29 99.4 0.8 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 EMG46779.1 - 1.8e-25 90.1 7.0 8.3e-24 84.7 0.1 3.9 3 1 0 3 3 3 1 SET domain RRM_6 PF14259.1 EMG46779.1 - 0.032 14.2 0.0 0.18 11.7 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 EMG46780.1 - 2.8e-72 242.9 0.0 6.2e-72 241.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG46780.1 - 2e-37 128.6 0.0 4e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EMG46780.1 - 3.3e-31 107.0 0.2 1.8e-14 53.4 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 EMG46780.1 - 5.4e-11 41.9 0.0 4e-10 39.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMG46780.1 - 0.012 14.6 0.0 0.026 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMG46780.1 - 0.068 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RNA_pol_L_2 PF13656.1 EMG46781.1 - 5.4e-24 83.4 0.1 9.1e-24 82.6 0.0 1.4 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EMG46781.1 - 4.6e-11 41.6 0.0 6.7e-11 41.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain PAH PF02671.16 EMG46782.1 - 2.3e-44 148.7 2.7 5.4e-18 64.3 0.2 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EMG46782.1 - 6.8e-43 144.5 0.1 2.8e-42 142.5 0.1 2.2 1 0 0 1 1 1 1 Sin3 family co-repressor Membr_traf_MHD PF10540.4 EMG46783.1 - 9.5e-16 57.8 0.3 9.5e-16 57.8 0.2 2.2 2 1 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EMG46783.1 - 2.2e-11 43.4 0.0 8.3e-11 41.5 0.0 2.1 1 0 0 1 1 1 1 C2 domain Ion_trans PF00520.26 EMG46784.1 - 8.4e-96 318.9 115.5 1.6e-33 115.6 9.7 6.5 7 0 0 7 7 7 5 Ion transport protein PKD_channel PF08016.7 EMG46784.1 - 0.57 8.5 66.0 0.13 10.6 6.7 7.0 6 1 0 6 6 6 0 Polycystin cation channel MRP-S33 PF08293.6 EMG46785.1 - 1.6e-28 98.5 1.2 1.9e-28 98.2 0.8 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 MIS13 PF08202.6 EMG46787.1 - 1.5e-44 152.2 7.4 1.5e-44 152.2 5.1 2.2 2 1 0 2 2 2 1 Mis12-Mtw1 protein family MBF1 PF08523.5 EMG46788.1 - 1.1e-26 92.5 1.6 1.1e-26 92.5 1.1 1.8 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EMG46788.1 - 1.5e-13 50.3 0.3 3.6e-13 49.1 0.1 1.7 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.1 EMG46788.1 - 2.8e-06 27.4 0.0 7.1e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.2 EMG46788.1 - 4.3e-06 26.6 0.0 6.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Steroid_dh PF02544.11 EMG46789.1 - 1.8e-35 121.9 9.1 1.8e-35 121.9 6.3 2.1 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Methyltransf_31 PF13847.1 EMG46790.1 - 1.7e-12 47.1 0.1 6.6e-12 45.2 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EMG46790.1 - 4.4e-11 42.4 0.0 5.9e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EMG46790.1 - 1.3e-09 38.6 0.0 1.9e-08 34.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.11 EMG46790.1 - 1.6e-08 33.8 0.0 2e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 EMG46790.1 - 5.2e-08 33.2 0.0 2.1e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMG46790.1 - 1.3e-07 31.6 0.0 3.3e-07 30.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMG46790.1 - 1.6e-05 24.7 0.0 3.7e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EMG46790.1 - 1.8e-05 24.2 0.0 3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EMG46790.1 - 5e-05 23.6 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EMG46790.1 - 6e-05 21.8 0.0 8.8e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 EMG46790.1 - 0.00049 19.2 0.0 0.00073 18.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EMG46790.1 - 0.0011 19.4 0.0 0.003 17.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EMG46790.1 - 0.0041 17.1 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase UPF0020 PF01170.13 EMG46790.1 - 0.011 15.3 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_16 PF10294.4 EMG46790.1 - 0.06 12.8 0.0 0.091 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 EMG46790.1 - 0.062 12.4 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_2 PF00891.13 EMG46790.1 - 0.063 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_32 PF13679.1 EMG46790.1 - 0.081 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain zf-ZPR1 PF03367.8 EMG46791.1 - 1.2e-115 382.1 3.0 3.4e-58 195.3 0.0 2.4 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Cytochrom_C_2 PF01322.15 EMG46791.1 - 0.077 13.5 5.5 2.8 8.5 0.4 3.4 3 0 0 3 3 3 0 Cytochrome C' UPF0547 PF10571.4 EMG46791.1 - 0.2 11.3 5.3 5.1 6.8 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 DZR PF12773.2 EMG46791.1 - 0.52 10.1 8.3 18 5.2 1.7 3.6 3 1 0 3 3 3 0 Double zinc ribbon Cys_rich_CPXG PF14255.1 EMG46791.1 - 2.5 8.0 7.5 9.1 6.1 0.1 3.3 3 0 0 3 3 3 0 Cysteine-rich CPXCG WD40 PF00400.27 EMG46792.1 - 3.8e-56 185.0 26.7 2.4e-11 43.0 1.2 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EMG46792.1 - 7.3e-15 54.0 10.3 0.0051 15.0 0.6 6.3 1 1 4 5 5 5 5 Nucleoporin Nup120/160 F-box-like PF12937.2 EMG46792.1 - 4.3e-14 51.9 3.0 9.3e-14 50.8 2.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMG46792.1 - 4.1e-12 45.4 2.3 9.9e-12 44.2 1.6 1.7 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.1 EMG46792.1 - 1.5e-06 27.9 0.1 0.054 13.2 0.0 4.2 2 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region PRANC PF09372.5 EMG46792.1 - 0.047 13.6 0.2 0.047 13.6 0.1 2.3 2 0 0 2 2 2 0 PRANC domain CBM_21 PF03370.8 EMG46794.1 - 3.7e-37 126.7 1.9 3.7e-37 126.7 1.3 2.9 4 0 0 4 4 4 1 Putative phosphatase regulatory subunit PBP1_TM PF14812.1 EMG46794.1 - 3.4 8.0 20.4 2.3 8.5 3.4 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FMO-like PF00743.14 EMG46795.1 - 8.7e-41 139.7 0.3 7.8e-21 73.8 0.2 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EMG46795.1 - 3.5e-18 66.3 0.0 7.4e-17 62.0 0.0 2.8 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMG46795.1 - 6e-13 48.8 0.0 1.3e-11 44.5 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMG46795.1 - 3.8e-11 43.2 0.0 5.2e-10 39.5 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMG46795.1 - 1e-07 30.7 0.0 5.2e-07 28.4 0.0 1.9 1 1 0 1 1 1 1 HI0933-like protein K_oxygenase PF13434.1 EMG46795.1 - 1.2e-07 30.9 0.0 2.9e-05 23.1 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EMG46795.1 - 1.1e-06 28.5 0.0 3.8e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMG46795.1 - 4.4e-06 25.8 0.0 0.014 14.2 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMG46795.1 - 0.00018 21.8 0.2 1.3 9.4 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EMG46795.1 - 0.0066 16.6 0.1 0.14 12.4 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.12 EMG46795.1 - 0.032 13.3 0.0 0.4 9.7 0.0 2.2 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.2 EMG46795.1 - 0.095 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HORMA PF02301.13 EMG46796.1 - 1.1e-39 136.1 0.5 1.1e-39 136.1 0.3 1.9 2 0 0 2 2 2 1 HORMA domain PSCyt3 PF07627.6 EMG46796.1 - 0.069 13.0 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) DUF1459 PF07312.6 EMG46796.1 - 0.1 12.5 0.2 0.23 11.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1459) Zn_clus PF00172.13 EMG46797.1 - 4.4e-07 29.6 8.0 4.4e-07 29.6 5.5 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LCM PF04072.9 EMG46799.1 - 1.2e-22 80.3 0.0 2.9e-22 79.1 0.0 1.5 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase Kelch_3 PF13415.1 EMG46799.1 - 1.9e-21 75.6 1.3 1.7e-07 31.2 0.0 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.1 EMG46799.1 - 1.2e-19 69.7 2.1 5e-11 42.2 0.0 5.0 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.1 EMG46799.1 - 1.5e-14 53.5 1.5 0.0011 18.9 0.0 6.4 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.1 EMG46799.1 - 1.8e-13 50.0 7.5 7.1e-05 22.8 0.0 6.3 5 1 1 6 6 6 2 Kelch motif Kelch_2 PF07646.10 EMG46799.1 - 1.5e-08 34.0 0.3 0.0032 17.1 0.0 4.4 4 1 1 5 5 5 2 Kelch motif Rax2 PF12768.2 EMG46799.1 - 2.1e-05 23.8 0.7 0.037 13.2 0.2 2.9 1 1 2 3 3 3 2 Cortical protein marker for cell polarity Kelch_1 PF01344.20 EMG46799.1 - 3.2e-05 23.3 4.8 0.2 11.2 0.0 5.5 6 0 0 6 6 6 2 Kelch motif Methyltransf_32 PF13679.1 EMG46799.1 - 0.12 12.0 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PH PF00169.24 EMG46800.1 - 3.8e-09 36.6 0.6 1.7e-08 34.5 0.4 2.2 1 0 0 1 1 1 1 PH domain XkdW PF09636.5 EMG46800.1 - 0.26 11.1 7.4 1 9.2 0.0 4.1 3 1 2 5 5 5 0 XkdW protein Fungal_trans PF04082.13 EMG46801.1 - 4.7e-22 78.1 0.0 4.7e-22 78.1 0.0 2.3 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG46801.1 - 1.1e-09 37.9 14.7 2.1e-09 37.1 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1440 PF07274.7 EMG46801.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1440) Rpn3_C PF08375.6 EMG46802.1 - 4.8e-25 87.7 0.7 4.8e-25 87.7 0.5 2.0 3 0 0 3 3 3 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EMG46802.1 - 9.3e-22 77.3 0.3 9.3e-22 77.3 0.2 2.5 4 1 0 4 4 4 1 PCI domain PCI_Csn8 PF10075.4 EMG46802.1 - 0.0004 20.1 0.3 0.014 15.1 0.0 2.6 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 DUF3237 PF11578.3 EMG46803.1 - 6.9e-12 44.9 0.0 7.8e-12 44.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) DUF2577 PF10844.3 EMG46803.1 - 0.12 12.3 0.1 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2577) Ras PF00071.17 EMG46804.1 - 8.3e-65 217.1 0.2 1e-64 216.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMG46804.1 - 1.1e-20 74.2 0.0 1.6e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMG46804.1 - 4.9e-17 61.7 0.1 6.3e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMG46804.1 - 7.7e-08 31.7 0.0 8.9e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMG46804.1 - 5.4e-05 22.6 0.3 0.00012 21.5 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMG46804.1 - 6.7e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EMG46804.1 - 0.00055 19.1 0.0 0.00083 18.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EMG46804.1 - 0.0012 18.9 0.0 0.0025 17.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EMG46804.1 - 0.0018 18.4 0.0 0.03 14.5 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMG46804.1 - 0.0062 16.5 0.2 0.073 13.0 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EMG46804.1 - 0.024 13.8 0.0 0.068 12.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EMG46804.1 - 0.03 13.8 0.1 1.2 8.5 0.0 2.4 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EMG46804.1 - 0.035 13.6 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain PixA PF12306.3 EMG46804.1 - 0.075 12.8 0.3 0.24 11.2 0.1 1.8 2 0 0 2 2 2 0 Inclusion body protein FeoB_N PF02421.13 EMG46804.1 - 0.1 11.8 0.0 0.72 9.1 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_5 PF07728.9 EMG46804.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TRAM_LAG1_CLN8 PF03798.11 EMG46805.1 - 7.2e-35 120.3 22.2 7.2e-35 120.3 15.4 1.8 2 0 0 2 2 2 1 TLC domain TatC PF00902.13 EMG46805.1 - 8.4 5.7 19.9 41 3.4 13.8 2.1 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) ArfGap PF01412.13 EMG46806.1 - 2.2e-27 95.1 6.7 3e-27 94.7 3.3 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 EMG46806.1 - 8.5e-10 38.7 1.2 4.9e-09 36.3 0.0 3.1 3 0 0 3 3 3 1 PH domain PH_9 PF15410.1 EMG46806.1 - 2.2e-06 27.8 0.5 1.4e-05 25.1 0.3 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.1 EMG46806.1 - 0.0059 16.6 0.0 0.017 15.1 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Pkinase PF00069.20 EMG46807.1 - 3.3e-69 232.9 0.0 5.3e-69 232.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG46807.1 - 3.2e-48 164.0 0.0 6.2e-48 163.1 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG46807.1 - 0.00045 19.2 0.0 0.0017 17.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMG46807.1 - 0.052 12.6 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MRP-L27 PF09809.4 EMG46809.1 - 7.1e-27 93.2 0.2 1.9e-26 91.9 0.2 1.7 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 CBFD_NFYB_HMF PF00808.18 EMG46809.1 - 1.5e-08 34.5 0.0 3e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMG46809.1 - 0.0033 17.5 0.1 0.0089 16.1 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Ribosomal_S8 PF00410.14 EMG46811.1 - 1.6e-22 79.6 0.0 2.3e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Peptidase_S24 PF00717.18 EMG46812.1 - 8.9e-08 31.6 0.0 2.7e-07 30.1 0.0 1.8 3 0 0 3 3 3 1 Peptidase S24-like Peptidase_S26 PF10502.4 EMG46812.1 - 5.4e-05 22.7 0.0 0.00017 21.1 0.0 1.8 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Ribophorin_II PF05817.9 EMG46813.1 - 5.5e-09 34.7 1.2 7.6e-09 34.3 0.8 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Med17 PF10156.4 EMG46814.1 - 3.9e-131 437.5 17.6 5e-131 437.2 12.2 1.0 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Glyco_hydro_81 PF03639.8 EMG46815.1 - 4.8e-208 692.5 16.6 4.8e-208 692.5 11.5 2.4 2 1 0 2 2 2 1 Glycosyl hydrolase family 81 DAO PF01266.19 EMG46816.1 - 7.8e-23 80.9 0.0 2.8e-22 79.1 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMG46816.1 - 0.0018 18.2 0.4 0.026 14.4 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMG46816.1 - 0.077 13.0 0.0 0.21 11.6 0.0 1.9 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Mqo PF06039.10 EMG46816.1 - 0.099 10.8 0.1 1.5 6.8 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) MFS_1 PF07690.11 EMG46818.1 - 2.9e-33 115.0 23.4 4e-33 114.5 15.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG46818.1 - 1e-10 40.8 7.1 1e-10 40.8 4.9 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EMG46818.1 - 0.0046 15.2 4.1 0.0065 14.7 0.4 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) GRASP55_65 PF04495.9 EMG46819.1 - 2.9e-43 147.1 0.0 5.1e-39 133.4 0.0 2.3 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PRANC PF09372.5 EMG46820.1 - 0.093 12.7 4.6 0.21 11.5 1.7 2.9 2 0 0 2 2 2 0 PRANC domain FNIP PF05725.7 EMG46820.1 - 0.74 9.8 28.0 9.2 6.3 0.0 8.8 9 2 0 9 9 9 0 FNIP Repeat F-box PF00646.28 EMG46820.1 - 3.3 7.4 6.2 4.1 7.1 0.2 4.0 5 0 0 5 5 5 0 F-box domain MFS_1 PF07690.11 EMG46821.1 - 3.1e-25 88.6 22.6 1.9e-24 86.0 12.5 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG46821.1 - 1.9e-09 36.6 3.0 1.9e-09 36.6 2.1 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 EMG46821.1 - 1.3e-06 27.0 7.2 9.7e-05 20.9 2.9 3.3 3 1 0 3 3 3 1 MFS/sugar transport protein PsbW PF07123.7 EMG46821.1 - 0.094 12.7 0.1 0.28 11.2 0.1 1.8 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) KilA-N PF04383.8 EMG46822.1 - 8.5e-09 35.0 0.0 6.3e-08 32.2 0.0 1.9 1 1 0 1 1 1 1 KilA-N domain Aldedh PF00171.17 EMG46823.1 - 9.9e-159 528.5 0.0 1.1e-158 528.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EMG46823.1 - 5.2e-05 22.5 0.0 0.00069 18.8 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Ank PF00023.25 EMG46825.1 - 8.7e-20 69.4 1.5 2.7e-08 33.2 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EMG46825.1 - 3.2e-17 62.6 0.6 6.2e-07 29.6 0.4 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EMG46825.1 - 1.6e-15 55.6 2.1 8.8e-06 25.4 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EMG46825.1 - 3.2e-15 55.8 1.2 1.1e-05 25.4 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMG46825.1 - 3e-12 46.6 0.7 1.3e-05 25.5 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeats (many copies) CorA PF01544.13 EMG46825.1 - 0.019 14.0 5.4 0.082 11.9 3.7 2.1 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Cyclin_N PF00134.18 EMG46826.1 - 2e-11 43.5 0.6 4.9e-11 42.2 0.4 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain PALP PF00291.20 EMG46827.1 - 8.1e-48 163.2 0.0 1e-47 162.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EMG46827.1 - 4.1e-15 55.2 0.0 5.7e-11 42.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain PBP-Tp47_a PF14889.1 EMG46827.1 - 0.013 14.7 0.0 0.033 13.5 0.0 1.7 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a TFIIS_M PF07500.9 EMG46828.1 - 3.3e-29 101.2 3.1 3.3e-29 101.2 2.2 2.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EMG46828.1 - 2.3e-18 65.5 7.6 3.8e-18 64.8 5.3 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EMG46828.1 - 5.4e-16 57.8 1.1 1.8e-15 56.1 0.8 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.3 EMG46828.1 - 0.004 16.4 2.2 0.0072 15.6 1.5 1.4 1 0 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain Elf1 PF05129.8 EMG46828.1 - 0.01 15.5 2.8 0.026 14.2 1.9 1.7 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Borrelia_REV PF03978.8 EMG46828.1 - 0.2 11.3 4.4 0.088 12.5 0.9 1.9 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein LINES_C PF14695.1 EMG46828.1 - 0.24 10.6 1.3 0.38 10.0 0.1 2.0 2 0 0 2 2 2 0 Lines C-terminus Zn_Tnp_IS1595 PF12760.2 EMG46828.1 - 0.88 9.4 6.2 4.8 7.0 4.4 2.0 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Ribosomal_S27 PF01599.14 EMG46828.1 - 2.6 7.9 6.5 3.2 7.6 0.6 2.4 1 1 1 2 2 2 0 Ribosomal protein S27a CSTF2_hinge PF14327.1 EMG46829.1 - 6.5e-16 58.1 5.7 9.6e-16 57.6 3.9 1.3 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EMG46829.1 - 1.9e-15 56.2 0.0 5.6e-15 54.7 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG46829.1 - 5.1e-12 45.5 0.0 1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG46829.1 - 2e-05 24.3 0.0 3.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rho_GDI PF02115.12 EMG46830.1 - 3.4e-12 46.2 0.1 4.3e-12 45.8 0.1 1.1 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Beach PF02138.13 EMG46830.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Beige/BEACH domain UQ_con PF00179.21 EMG46831.1 - 2.5e-37 127.4 0.0 3.2e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Phage_DsbA PF11126.3 EMG46831.1 - 0.096 12.7 0.2 0.2 11.7 0.2 1.6 1 1 0 1 1 1 0 Transcriptional regulator DsbA Astro_capsid PF03115.9 EMG46831.1 - 0.19 9.9 0.2 0.22 9.7 0.2 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Cwf_Cwc_15 PF04889.7 EMG46831.1 - 0.65 9.6 6.3 0.88 9.2 4.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Rtf2 PF04641.7 EMG46832.1 - 0.0046 16.2 0.1 0.0086 15.2 0.1 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger WD40 PF00400.27 EMG46832.1 - 0.03 14.2 0.3 0.2 11.6 0.0 2.7 3 0 0 3 3 3 0 WD domain, G-beta repeat ABC_tran PF00005.22 EMG46834.1 - 2.5e-52 176.8 0.1 6.1e-26 91.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 EMG46834.1 - 3.1e-38 131.0 40.7 5.6e-20 71.4 8.0 2.4 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.1 EMG46834.1 - 2.5e-17 63.7 21.3 1.1e-07 32.1 0.1 5.3 3 2 1 4 4 4 3 AAA domain DUF258 PF03193.11 EMG46834.1 - 2.4e-12 46.3 2.8 1.3e-05 24.4 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SMC_N PF02463.14 EMG46834.1 - 8e-11 41.5 1.2 2.2e-06 27.0 0.0 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EMG46834.1 - 1.3e-10 41.5 1.5 0.0002 21.5 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EMG46834.1 - 1.3e-09 38.8 0.3 0.00088 20.0 0.0 3.3 3 0 0 3 3 2 2 AAA domain T2SE PF00437.15 EMG46834.1 - 1.9e-09 36.8 2.0 0.00022 20.2 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 EMG46834.1 - 4.1e-09 36.7 0.5 0.0015 18.5 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.1 EMG46834.1 - 1.7e-08 34.7 2.6 0.0049 17.1 0.0 3.9 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.1 EMG46834.1 - 4.7e-08 32.4 1.6 0.0046 16.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 EMG46834.1 - 1e-07 31.7 0.3 0.018 14.9 0.0 3.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Arch_ATPase PF01637.13 EMG46834.1 - 1.9e-07 31.0 0.0 0.0018 18.0 0.0 2.7 2 0 0 2 2 2 2 Archaeal ATPase AAA_28 PF13521.1 EMG46834.1 - 2.1e-07 31.0 0.2 0.013 15.4 0.1 2.5 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 EMG46834.1 - 6e-07 29.0 1.0 0.0077 15.6 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EMG46834.1 - 1.2e-06 28.2 0.1 0.045 13.3 0.0 2.9 2 0 0 2 2 2 2 NACHT domain AAA PF00004.24 EMG46834.1 - 1.7e-06 28.2 0.1 0.03 14.5 0.0 4.1 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EMG46834.1 - 2.3e-06 27.2 0.9 0.00027 20.5 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.1 EMG46834.1 - 3.4e-06 26.6 0.0 0.52 9.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.1 EMG46834.1 - 3.4e-06 26.9 0.2 0.039 13.8 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EMG46834.1 - 4.1e-06 26.4 0.0 0.085 12.6 0.0 2.7 2 1 0 2 2 2 2 Part of AAA domain MMR_HSR1 PF01926.18 EMG46834.1 - 7.9e-06 25.8 0.1 0.078 12.9 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_5 PF07728.9 EMG46834.1 - 8.6e-06 25.5 0.3 0.26 11.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EMG46834.1 - 9.1e-06 25.3 2.4 0.12 11.7 0.0 3.3 3 0 0 3 3 3 2 AAA-like domain AAA_15 PF13175.1 EMG46834.1 - 2e-05 23.8 28.6 0.054 12.5 0.1 5.8 5 1 1 6 6 5 4 AAA ATPase domain AAA_33 PF13671.1 EMG46834.1 - 2e-05 24.4 0.1 0.025 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Pox_A32 PF04665.7 EMG46834.1 - 2.2e-05 23.8 0.3 0.094 12.0 0.1 2.6 2 0 0 2 2 2 2 Poxvirus A32 protein ATP_bind_1 PF03029.12 EMG46834.1 - 3.6e-05 23.4 0.1 0.13 11.7 0.1 2.6 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 EMG46834.1 - 4.3e-05 23.1 0.3 0.3 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EMG46834.1 - 6.1e-05 23.1 0.1 0.085 13.0 0.0 2.9 2 0 0 2 2 2 1 RNA helicase Septin PF00735.13 EMG46834.1 - 8.7e-05 21.6 0.3 0.069 12.1 0.1 2.7 2 0 0 2 2 2 1 Septin Miro PF08477.8 EMG46834.1 - 0.0001 22.7 0.0 0.23 11.9 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein UPF0079 PF02367.12 EMG46834.1 - 0.00012 21.6 0.2 0.61 9.7 0.0 2.6 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EMG46834.1 - 0.00019 21.0 0.1 0.75 9.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EMG46834.1 - 0.00029 20.5 0.2 0.27 10.9 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EMG46834.1 - 0.00033 20.4 0.2 1.6 8.4 0.0 3.3 3 0 0 3 3 3 1 NTPase PduV-EutP PF10662.4 EMG46834.1 - 0.00034 20.1 1.3 0.9 9.0 0.1 3.0 3 0 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 EMG46834.1 - 0.0006 20.2 4.3 0.0033 17.7 0.3 3.9 3 1 1 4 4 3 2 AAA domain SRPRB PF09439.5 EMG46834.1 - 0.00061 19.0 0.4 0.8 8.8 0.0 2.6 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Zeta_toxin PF06414.7 EMG46834.1 - 0.00064 18.8 0.1 0.42 9.6 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin ATP-synt_ab PF00006.20 EMG46834.1 - 0.00066 19.2 0.0 0.062 12.8 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.17 EMG46834.1 - 0.00085 18.2 0.1 0.33 9.7 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain IstB_IS21 PF01695.12 EMG46834.1 - 0.0014 18.0 0.1 5.7 6.3 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein Rad17 PF03215.10 EMG46834.1 - 0.0018 17.0 0.1 0.85 8.2 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein PRK PF00485.13 EMG46834.1 - 0.0028 17.2 0.1 0.69 9.4 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.17 EMG46834.1 - 0.0029 17.0 0.2 2.5 7.5 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain PIF1 PF05970.9 EMG46834.1 - 0.0044 16.0 0.4 1.2 8.0 0.0 2.5 2 0 0 2 2 2 1 PIF1-like helicase KAP_NTPase PF07693.9 EMG46834.1 - 0.0067 15.4 0.0 2.6 6.9 0.0 2.4 2 0 0 2 2 2 1 KAP family P-loop domain TIP49 PF06068.8 EMG46834.1 - 0.017 13.9 0.0 0.3 9.7 0.0 2.3 2 0 0 2 2 2 0 TIP49 C-terminus Sigma54_activat PF00158.21 EMG46834.1 - 0.024 14.1 0.1 2.9 7.3 0.0 3.1 3 0 0 3 3 2 0 Sigma-54 interaction domain Thymidylate_kin PF02223.12 EMG46834.1 - 0.028 13.8 0.0 10 5.4 0.0 2.8 2 0 0 2 2 2 0 Thymidylate kinase GTP_EFTU PF00009.22 EMG46834.1 - 0.047 13.1 0.1 2.5 7.4 0.1 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain KaiC PF06745.8 EMG46834.1 - 0.048 12.7 1.0 8.3 5.4 0.0 3.6 3 1 0 3 3 3 0 KaiC AAA_13 PF13166.1 EMG46834.1 - 0.051 12.0 14.3 0.059 11.8 0.1 4.3 4 1 0 4 4 4 0 AAA domain DUF87 PF01935.12 EMG46834.1 - 0.055 13.2 8.0 1.4 8.6 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function DUF87 Mg_chelatase PF01078.16 EMG46834.1 - 0.066 12.3 0.4 1.7 7.7 0.0 3.0 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI UPF0160 PF03690.8 EMG46835.1 - 2.9e-127 424.4 0.0 3.3e-127 424.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) SUI1 PF01253.17 EMG46836.1 - 4.9e-16 58.3 0.5 1.5e-15 56.7 0.4 1.9 1 0 0 1 1 1 1 Translation initiation factor SUI1 Kin17_mid PF10357.4 EMG46836.1 - 1.3e-05 24.8 1.6 7.3e-05 22.4 0.2 2.4 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein PUA PF01472.15 EMG46836.1 - 0.041 13.6 0.0 0.092 12.4 0.0 1.6 1 0 0 1 1 1 0 PUA domain UBX PF00789.15 EMG46837.1 - 8.9e-11 41.7 0.4 1.3e-09 38.0 0.0 2.7 2 1 0 2 2 2 1 UBX domain Thioredoxin_7 PF13899.1 EMG46837.1 - 3.9e-05 23.5 0.1 9.7e-05 22.3 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin-like DUF2410 PF10307.4 EMG46837.1 - 0.088 12.1 1.7 0.15 11.4 1.2 1.3 1 0 0 1 1 1 0 Hypothetical protein (DUF2410) DUF605 PF04652.11 EMG46837.1 - 4.3 6.6 24.4 0.88 8.9 8.4 2.4 2 0 0 2 2 2 0 Vta1 like DUF788 PF05620.6 EMG46838.1 - 3.8e-55 186.3 0.0 4.3e-55 186.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) CwfJ_C_1 PF04677.10 EMG46839.1 - 2.3e-25 88.6 0.0 3.8e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EMG46839.1 - 8.7e-21 74.2 0.8 1.5e-20 73.4 0.5 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-MYND PF01753.13 EMG46840.1 - 0.0037 17.0 0.0 0.014 15.2 0.0 2.0 1 1 0 1 1 1 1 MYND finger SET PF00856.23 EMG46840.1 - 0.0055 17.0 0.7 0.0072 16.6 0.5 1.3 1 1 0 1 1 1 1 SET domain YHS PF04945.8 EMG46840.1 - 0.11 12.3 7.0 0.22 11.4 2.9 2.6 2 0 0 2 2 2 0 YHS domain Bac_rhodopsin PF01036.13 EMG46841.1 - 1.9e-73 246.4 20.2 2.3e-73 246.2 14.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.1 EMG46841.1 - 1.3 8.4 13.5 1.9 7.8 2.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) UCH PF00443.24 EMG46842.1 - 2.9e-30 105.3 9.5 7.8e-28 97.3 3.7 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMG46842.1 - 1.4e-05 24.7 20.8 0.0011 18.4 14.5 3.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Nitr_red_assoc PF09655.5 EMG46842.1 - 0.012 15.8 0.3 0.05 13.9 0.2 2.1 1 0 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) DUF2457 PF10446.4 EMG46842.1 - 0.082 11.6 23.8 0.17 10.6 16.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 EMG46842.1 - 0.28 9.6 22.1 0.024 13.1 11.6 1.8 2 0 0 2 2 2 0 Daxx Family CDC45 PF02724.9 EMG46842.1 - 5.2 4.9 16.1 11 3.9 11.1 1.5 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EMG46842.1 - 7.1 4.4 29.9 0.34 8.7 16.1 2.0 2 0 0 2 2 2 0 Nop14-like family 5-FTHF_cyc-lig PF01812.15 EMG46843.1 - 4.3e-42 143.9 0.0 5e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Fungal_trans PF04082.13 EMG46844.1 - 1.1e-15 57.1 0.4 2e-15 56.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG46844.1 - 3.4e-08 33.2 7.6 7.4e-08 32.1 5.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bac_rhodopsin PF01036.13 EMG46845.1 - 1.1e-68 230.9 21.2 1.2e-68 230.7 14.7 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein SPX PF03105.14 EMG46847.1 - 3e-51 174.8 4.0 5e-51 174.0 2.8 1.4 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EMG46847.1 - 3e-25 89.0 48.4 4.5e-25 88.4 33.5 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EMG46847.1 - 1e-14 53.9 48.5 2.5e-11 42.7 17.7 2.1 1 1 1 2 2 2 2 Citrate transporter PIG-P PF08510.7 EMG46847.1 - 3.3 7.3 9.7 0.076 12.6 0.6 2.8 3 0 0 3 3 3 0 PIG-P Kinesin PF00225.18 EMG46848.1 - 2e-100 335.7 1.4 3.2e-100 335.1 1.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Jnk-SapK_ap_N PF09744.4 EMG46848.1 - 0.057 13.3 0.4 0.057 13.3 0.3 3.2 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 IL5 PF02025.10 EMG46848.1 - 0.086 12.8 2.5 0.35 10.8 0.7 2.5 2 1 0 2 2 2 0 Interleukin 5 IncA PF04156.9 EMG46848.1 - 0.25 10.9 8.0 0.47 10.0 5.6 1.5 1 0 0 1 1 1 0 IncA protein TSC22 PF01166.13 EMG46848.1 - 0.45 10.5 8.4 1.4 8.9 1.3 3.6 1 1 2 3 3 3 0 TSC-22/dip/bun family DUF3573 PF12097.3 EMG46848.1 - 9.3 4.7 13.2 0.27 9.8 4.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Sugar_tr PF00083.19 EMG46849.1 - 6.9e-101 338.0 32.6 8.4e-101 337.7 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG46849.1 - 9.6e-23 80.4 36.6 1.5e-21 76.5 22.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 EMG46850.1 - 2.9e-41 141.3 2.5 8.2e-41 139.8 1.7 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG46850.1 - 1.5e-14 53.7 1.6 3.8e-11 42.5 0.2 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 EMG46850.1 - 0.083 12.2 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF159 PF02586.9 EMG46851.1 - 1.4e-43 148.8 0.6 1.4e-43 148.8 0.4 1.8 2 0 0 2 2 2 1 Uncharacterised ACR, COG2135 MRP-S28 PF10213.4 EMG46851.1 - 3.5e-35 120.8 4.5 8e-35 119.6 3.1 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein FAD_binding_3 PF01494.14 EMG46852.1 - 1.1e-18 67.4 1.4 1.4e-16 60.4 1.0 3.0 1 1 0 1 1 1 1 FAD binding domain PGAP1 PF07819.8 EMG46852.1 - 3.1e-06 26.9 0.0 5.9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EMG46852.1 - 2.4e-05 23.7 0.0 7.9e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Putative serine esterase (DUF676) DUF915 PF06028.6 EMG46852.1 - 0.0018 17.4 0.0 0.074 12.1 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.10 EMG46852.1 - 0.0023 16.9 0.3 0.0069 15.4 0.0 1.9 3 0 0 3 3 3 1 Lecithin:cholesterol acyltransferase Lycopene_cycl PF05834.7 EMG46852.1 - 0.003 16.5 0.0 0.16 10.8 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EMG46852.1 - 0.0041 17.0 0.0 0.012 15.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMG46852.1 - 0.0059 15.2 0.0 0.66 8.5 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.1 EMG46852.1 - 0.011 15.5 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding SE PF08491.5 EMG46852.1 - 0.03 13.1 0.0 0.056 12.2 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase DAO PF01266.19 EMG46852.1 - 0.072 11.9 0.0 0.17 10.7 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Aldedh PF00171.17 EMG46853.1 - 1.1e-113 380.0 0.0 1.3e-113 379.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMG46853.1 - 0.085 11.5 0.0 0.43 9.2 0.0 1.9 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Methyltransf_23 PF13489.1 EMG46854.1 - 1.9e-17 63.4 0.0 2.8e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMG46854.1 - 5.5e-17 62.0 0.4 2.8e-16 59.7 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMG46854.1 - 1.6e-11 44.4 0.0 3.4e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMG46854.1 - 1.7e-11 44.4 0.0 5.4e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMG46854.1 - 2.1e-10 40.4 0.1 7.9e-10 38.5 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMG46854.1 - 5.3e-09 36.6 0.0 1.3e-08 35.4 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMG46854.1 - 6e-06 26.2 0.0 1.4e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EMG46854.1 - 1.7e-05 23.9 0.0 0.038 12.9 0.0 2.2 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.13 EMG46854.1 - 3.3e-05 23.1 0.0 5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EMG46854.1 - 0.00093 18.3 0.1 0.002 17.2 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EMG46854.1 - 0.0035 16.7 0.0 0.0082 15.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain DUF3419 PF11899.3 EMG46854.1 - 0.0098 14.6 0.0 0.017 13.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) FmrO PF07091.6 EMG46854.1 - 0.016 14.1 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_24 PF13578.1 EMG46854.1 - 0.018 15.8 0.0 0.037 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EMG46854.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.6 EMG46854.1 - 0.18 11.2 0.8 1 8.7 0.0 2.3 2 1 0 2 2 2 0 Nodulation protein S (NodS) CMV_US PF08001.6 EMG46855.1 - 0.57 9.1 2.8 0.28 10.2 0.1 1.8 2 0 0 2 2 2 0 CMV US GalP_UDP_transf PF01087.17 EMG46856.1 - 1.2e-67 227.5 0.1 2e-67 226.7 0.1 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EMG46856.1 - 1.1e-62 210.4 0.8 2.4e-62 209.3 0.6 1.6 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DcpS_C PF11969.3 EMG46856.1 - 0.004 17.3 0.7 0.0085 16.3 0.5 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EMG46856.1 - 0.055 14.0 0.1 0.28 11.7 0.0 2.1 2 0 0 2 2 2 0 HIT domain GAF_2 PF13185.1 EMG46856.1 - 0.17 12.3 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 GAF domain Epimerase PF01370.16 EMG46857.1 - 6.7e-51 172.9 0.0 8e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMG46857.1 - 9e-14 50.9 0.0 8.4e-13 47.8 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EMG46857.1 - 1.3e-11 43.9 0.0 1.7e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EMG46857.1 - 1.5e-11 43.5 0.0 2.1e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EMG46857.1 - 7.4e-08 31.6 0.0 2.6e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Aldose_epim PF01263.15 EMG46858.1 - 4.3e-71 239.4 2.1 7e-71 238.7 0.6 1.9 1 1 1 2 2 2 1 Aldose 1-epimerase Epimerase PF01370.16 EMG46858.1 - 1.7e-48 165.1 0.0 2.4e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EMG46858.1 - 4.8e-24 84.0 0.2 9.2e-24 83.1 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EMG46858.1 - 1e-17 63.7 0.6 7.8e-17 60.8 0.1 2.4 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EMG46858.1 - 1.1e-17 63.8 0.1 4.4e-16 58.6 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EMG46858.1 - 4.7e-12 45.3 0.0 8.5e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EMG46858.1 - 5.7e-09 35.2 0.0 1e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EMG46858.1 - 7.1e-09 35.7 0.0 1.2e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMG46858.1 - 2.9e-08 33.5 0.0 5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMG46858.1 - 5.8e-08 32.9 0.0 1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 EMG46858.1 - 0.017 15.0 0.1 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 EMG46858.1 - 0.025 13.8 0.2 0.054 12.7 0.1 1.6 1 0 0 1 1 1 0 NmrA-like family UDPG_MGDP_dh_N PF03721.9 EMG46858.1 - 0.082 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EMG46858.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GalKase_gal_bdg PF10509.4 EMG46859.1 - 3.3e-20 71.0 0.2 5.7e-20 70.3 0.1 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 EMG46859.1 - 1.2e-15 57.2 0.2 3.1e-15 55.9 0.1 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EMG46859.1 - 3.6e-10 39.8 0.0 7.5e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Pox_D2 PF04701.8 EMG46859.1 - 0.039 13.9 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 Pox virus D2 protein SNF2_N PF00176.18 EMG46860.1 - 6.5e-72 241.8 0.1 1.7e-71 240.5 0.1 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 EMG46860.1 - 5e-29 100.4 1.4 5e-29 100.4 1.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) Chromo PF00385.19 EMG46860.1 - 1e-22 79.5 6.2 1.3e-13 50.3 1.6 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EMG46860.1 - 9.5e-15 54.2 0.0 4.3e-14 52.1 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Staphostatin_B PF09023.5 EMG46860.1 - 0.015 15.1 0.2 5.3 6.8 0.0 2.8 2 0 0 2 2 2 0 Staphostatin B ABC_tran PF00005.22 EMG46861.1 - 5.5e-36 123.8 0.0 1.1e-17 64.5 0.0 2.5 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EMG46861.1 - 7.7e-13 49.0 8.0 0.0087 16.0 0.1 4.3 2 2 2 4 4 4 4 AAA domain RLI PF04068.10 EMG46861.1 - 2.4e-12 46.1 5.8 6e-12 44.9 4.0 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.14 EMG46861.1 - 1.7e-10 40.5 4.1 0.00047 19.4 0.5 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 EMG46861.1 - 2.1e-08 33.4 3.0 2.1e-08 33.4 2.1 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_17 PF13207.1 EMG46861.1 - 3.1e-06 28.0 0.2 0.079 13.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA PF00004.24 EMG46861.1 - 3.3e-06 27.3 0.0 0.025 14.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EMG46861.1 - 3.9e-06 26.3 0.0 0.0038 16.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EMG46861.1 - 4.9e-06 25.8 2.7 0.091 11.7 0.1 4.7 4 1 1 5 5 5 1 AAA ATPase domain Fer4_7 PF12838.2 EMG46861.1 - 2.8e-05 24.4 7.0 0.00024 21.4 0.2 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_18 PF13238.1 EMG46861.1 - 3e-05 24.3 0.1 0.12 12.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain Fer4_6 PF12837.2 EMG46861.1 - 3.9e-05 23.3 2.8 3.9e-05 23.3 2.0 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_22 PF13401.1 EMG46861.1 - 6.1e-05 23.1 0.5 0.063 13.4 0.0 2.8 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EMG46861.1 - 0.00014 21.3 0.2 0.14 11.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EMG46861.1 - 0.00019 20.6 2.5 0.42 9.7 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function, DUF258 Fer4_21 PF14697.1 EMG46861.1 - 0.00021 21.0 12.2 0.00043 20.0 8.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain VirE PF05272.6 EMG46861.1 - 0.00036 20.0 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 2 Virulence-associated protein E Fer4_2 PF12797.2 EMG46861.1 - 0.00072 19.3 2.4 0.00072 19.3 1.6 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain RNA_helicase PF00910.17 EMG46861.1 - 0.00086 19.4 0.1 0.18 11.9 0.0 2.6 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.7 EMG46861.1 - 0.0014 18.2 1.6 0.79 9.3 0.0 3.3 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.1 EMG46861.1 - 0.0027 17.6 0.0 0.58 10.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Fer4_9 PF13187.1 EMG46861.1 - 0.0032 17.7 1.9 0.0032 17.7 1.3 2.2 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EMG46861.1 - 0.0038 16.9 1.3 0.0038 16.9 0.9 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_33 PF13671.1 EMG46861.1 - 0.0042 16.9 0.0 1.2 9.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain Fer4_16 PF13484.1 EMG46861.1 - 0.0058 17.3 0.1 0.0058 17.3 0.1 2.7 2 1 1 3 3 2 1 4Fe-4S double cluster binding domain MobB PF03205.9 EMG46861.1 - 0.0059 16.3 0.6 1.5 8.4 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_3 PF12798.2 EMG46861.1 - 0.0059 17.0 4.2 0.0059 17.0 2.9 2.7 2 0 0 2 2 2 1 4Fe-4S binding domain Miro PF08477.8 EMG46861.1 - 0.0063 17.0 0.0 6.5 7.2 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein UPF0079 PF02367.12 EMG46861.1 - 0.0072 15.9 0.2 0.087 12.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SbcCD_C PF13558.1 EMG46861.1 - 0.0089 15.9 0.0 4.3 7.3 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit HflK_N PF12221.3 EMG46861.1 - 0.0093 15.6 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 1 Bacterial membrane protein N terminal SRP54 PF00448.17 EMG46861.1 - 0.017 14.5 3.4 0.49 9.7 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.17 EMG46861.1 - 0.027 13.3 0.2 1.3 7.7 0.0 2.5 2 1 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.1 EMG46861.1 - 0.046 13.2 0.7 0.62 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EMG46861.1 - 0.055 13.4 0.0 14 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 EMG46861.1 - 0.059 12.0 0.0 1.4 7.5 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 EMG46861.1 - 0.065 12.9 0.7 0.72 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EMG46861.1 - 0.074 12.9 0.2 13 5.6 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_13 PF13166.1 EMG46861.1 - 0.12 10.8 0.0 0.12 10.8 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.1 EMG46861.1 - 0.14 11.7 0.2 3.2 7.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 EMG46861.1 - 0.2 11.0 1.3 13 5.0 0.1 3.2 4 0 0 4 4 3 0 Thymidylate kinase Fer4_4 PF12800.2 EMG46861.1 - 0.44 11.0 14.6 0.052 13.9 1.7 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.1 EMG46861.1 - 0.53 10.3 10.7 1.8 8.6 7.6 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_23 PF13476.1 EMG46861.1 - 0.56 10.5 7.2 0.55 10.5 0.1 2.6 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EMG46861.1 - 1 8.8 3.9 0.64 9.5 0.0 2.6 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Fer4_15 PF13459.1 EMG46861.1 - 4.3 7.9 8.4 0.13 12.8 1.0 2.1 2 0 0 2 2 1 0 4Fe-4S single cluster domain Fer4_17 PF13534.1 EMG46861.1 - 4.6 7.6 12.7 0.31 11.4 1.1 2.6 1 1 2 3 3 3 0 4Fe-4S dicluster domain Sec62 PF03839.11 EMG46862.1 - 3.4e-50 170.5 3.8 3.4e-50 170.5 2.7 2.2 2 0 0 2 2 2 1 Translocation protein Sec62 WD40 PF00400.27 EMG46862.1 - 8.3e-08 31.8 2.0 0.018 14.8 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat MafB19-deam PF14437.1 EMG46862.1 - 0.19 11.3 1.5 9.6 5.8 0.0 2.3 2 0 0 2 2 2 0 MafB19-like deaminase ECH_C PF13766.1 EMG46863.1 - 1.3e-26 93.0 0.0 2.4e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EMG46863.1 - 1.9e-22 79.5 0.0 5.7e-22 78.0 0.0 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Actin PF00022.14 EMG46864.1 - 2e-62 210.8 0.0 4.8e-50 170.1 0.0 2.3 2 0 0 2 2 2 2 Actin Peptidase_M16 PF00675.15 EMG46865.1 - 5.9e-46 155.9 0.0 1.2e-45 154.9 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EMG46865.1 - 9.8e-33 113.3 0.0 5.1e-32 111.0 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain Ada3 PF10198.4 EMG46866.1 - 3.4e-43 146.5 4.9 3.4e-43 146.5 3.4 3.4 3 1 0 3 3 3 1 Histone acetyltransferases subunit 3 Glyco_transf_20 PF00982.16 EMG46867.1 - 1.9e-148 494.8 0.2 2.6e-148 494.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EMG46867.1 - 4.7e-79 264.6 0.0 8.3e-79 263.7 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase RRM_1 PF00076.17 EMG46868.1 - 1.2e-84 277.9 8.1 9e-22 76.4 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG46868.1 - 4.9e-53 177.0 0.5 2.9e-13 49.5 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG46868.1 - 3.7e-40 135.5 1.0 1.1e-10 41.2 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EMG46868.1 - 5.9e-27 93.1 0.3 5.6e-26 90.0 0.1 2.8 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain CbiG_mid PF11761.3 EMG46868.1 - 3e-05 24.1 0.3 0.69 10.1 0.0 4.1 4 1 0 4 4 4 1 Cobalamin biosynthesis central region Nup35_RRM_2 PF14605.1 EMG46868.1 - 0.00086 19.0 1.3 1.9 8.3 0.0 3.9 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EMG46868.1 - 0.0016 18.1 1.6 0.51 10.1 0.1 3.3 3 0 0 3 3 3 1 Limkain b1 OB_RNB PF08206.6 EMG46868.1 - 0.012 15.0 0.9 3 7.4 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain YflT PF11181.3 EMG46868.1 - 0.02 15.0 5.9 0.46 10.6 0.4 3.5 3 0 0 3 3 3 0 Heat induced stress protein YflT Arc_PepC PF06819.6 EMG46868.1 - 0.076 12.9 1.9 0.22 11.4 1.3 1.7 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain PAT1 PF09770.4 EMG46868.1 - 0.8 7.8 23.3 1.3 7.1 16.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Arrestin_C PF02752.17 EMG46869.1 - 3.2e-19 69.3 2.7 1.9e-17 63.6 0.1 3.1 3 1 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EMG46869.1 - 1.2e-11 44.6 0.4 1.9e-06 27.8 0.0 3.2 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Receptor_2B4 PF11465.3 EMG46869.1 - 0.098 12.5 0.4 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 Abhydrolase_6 PF12697.2 EMG46870.1 - 9.6e-15 55.0 0.0 1.4e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMG46870.1 - 2e-12 47.1 0.0 3.1e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMG46870.1 - 1.7e-06 27.8 0.0 4.7e-06 26.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EMG46870.1 - 0.0079 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Cutinase VirJ PF06057.6 EMG46870.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Lipase_3 PF01764.20 EMG46870.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) 14-3-3 PF00244.15 EMG46871.1 - 5.2e-114 379.2 4.0 6.3e-114 378.9 2.8 1.1 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 EMG46871.1 - 0.026 14.4 1.2 0.057 13.3 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M24 PF00557.19 EMG46872.1 - 2.6e-10 40.2 0.0 6.1e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Metallopeptidase family M24 PHD PF00628.24 EMG46873.1 - 9.6e-11 41.2 7.1 3e-10 39.6 4.9 1.9 1 0 0 1 1 1 1 PHD-finger Ferrochelatase PF00762.14 EMG46873.1 - 0.1 11.5 0.3 0.42 9.5 0.2 2.1 2 1 0 2 2 2 0 Ferrochelatase Vasohibin PF14822.1 EMG46873.1 - 0.1 11.6 1.8 4.8 6.1 0.4 2.2 2 0 0 2 2 2 0 Vasohibin NEP PF10167.4 EMG46873.1 - 3.9 7.1 12.4 0.25 11.0 4.1 2.2 3 0 0 3 3 3 0 Uncharacterised conserved protein DUF972 PF06156.8 EMG46873.1 - 6.2 7.2 15.7 0.096 13.0 5.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF972) MgsA_C PF12002.3 EMG46874.1 - 6.2e-57 191.9 0.0 2.3e-56 190.0 0.0 2.0 1 1 1 2 2 2 1 MgsA AAA+ ATPase C terminal RuvB_N PF05496.7 EMG46874.1 - 9.4e-18 64.1 0.0 2.5e-17 62.7 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 EMG46874.1 - 5.2e-16 59.0 0.0 1.2e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMG46874.1 - 6.1e-06 26.0 0.4 9.2e-05 22.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EMG46874.1 - 7.2e-06 26.0 0.0 2.4e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.21 EMG46874.1 - 2.2e-05 24.0 0.0 0.00023 20.6 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain TIP49 PF06068.8 EMG46874.1 - 2.6e-05 23.1 0.4 0.0008 18.2 0.0 2.8 1 1 1 3 3 3 1 TIP49 C-terminus AAA_14 PF13173.1 EMG46874.1 - 5.8e-05 23.0 0.0 0.00023 21.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMG46874.1 - 0.0002 21.4 1.6 0.005 16.8 0.0 3.0 1 1 2 3 3 3 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 EMG46874.1 - 0.0011 19.0 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain zf-C2H2 PF00096.21 EMG46874.1 - 0.0024 18.1 1.8 0.0051 17.0 1.2 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type AAA_22 PF13401.1 EMG46874.1 - 0.0042 17.2 0.2 0.074 13.1 0.1 2.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EMG46874.1 - 0.0046 16.1 0.1 1.1 8.4 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI zf-C2H2_4 PF13894.1 EMG46874.1 - 0.0079 16.4 1.6 0.018 15.3 1.1 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger DUF815 PF05673.8 EMG46874.1 - 0.01 14.7 0.0 0.034 13.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) zf-C2HC_2 PF13913.1 EMG46874.1 - 0.027 14.1 1.0 0.049 13.3 0.7 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type AAA_3 PF07726.6 EMG46874.1 - 0.028 14.0 0.0 0.081 12.5 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-Di19 PF05605.7 EMG46874.1 - 0.031 14.3 0.5 0.068 13.2 0.4 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding IstB_IS21 PF01695.12 EMG46874.1 - 0.055 12.8 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.22 EMG46874.1 - 5.5 7.2 6.3 1.3 9.3 0.1 3.1 3 1 0 3 3 3 0 ABC transporter TFIIB PF00382.14 EMG46875.1 - 5.7e-41 138.1 0.0 3.1e-21 74.9 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EMG46875.1 - 2.5e-13 49.1 1.1 4.4e-13 48.3 0.7 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.1 EMG46875.1 - 7.6 5.8 6.3 1.6 8.0 1.5 2.1 2 1 0 2 2 2 0 zinc-ribbon domain Fungal_trans PF04082.13 EMG46876.1 - 4.9e-17 61.6 2.3 5.6e-17 61.4 0.4 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG46876.1 - 1.1e-08 34.8 11.6 3.2e-08 33.3 8.1 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tropomyosin PF00261.15 EMG46876.1 - 0.0038 16.3 0.1 0.016 14.3 0.0 1.9 2 0 0 2 2 2 1 Tropomyosin Rad51 PF08423.6 EMG46876.1 - 0.019 13.8 0.1 0.037 12.9 0.1 1.5 1 0 0 1 1 1 0 Rad51 Zn_clus PF00172.13 EMG46877.1 - 1.6e-08 34.3 7.5 2.6e-08 33.6 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMG46877.1 - 0.005 15.7 10.7 0.11 11.4 0.3 3.9 3 1 0 3 3 3 2 Fungal specific transcription factor domain Serinc PF03348.10 EMG46877.1 - 0.66 8.6 11.3 1.4 7.5 7.8 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) Dala_Dala_lig_N PF01820.16 EMG46877.1 - 0.94 9.8 6.7 36 4.6 3.9 3.4 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus Septin PF00735.13 EMG46878.1 - 3.1e-114 380.7 0.1 3.1e-114 380.7 0.1 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EMG46878.1 - 2e-06 27.7 0.0 4.8e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMG46878.1 - 0.0002 20.5 1.8 0.00036 19.7 0.1 2.2 2 1 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 EMG46878.1 - 0.0012 19.3 0.0 0.0061 17.0 0.0 2.3 1 1 1 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EMG46878.1 - 0.0022 17.4 0.1 0.022 14.1 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 EMG46878.1 - 0.0029 17.1 0.0 0.0064 15.9 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family IIGP PF05049.8 EMG46878.1 - 0.0037 16.1 0.0 0.0076 15.1 0.0 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.1 EMG46878.1 - 0.0037 17.3 0.4 0.015 15.4 0.0 2.3 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMG46878.1 - 0.0047 16.9 0.1 0.023 14.7 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EMG46878.1 - 0.0078 15.8 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 EMG46878.1 - 0.013 14.5 0.4 0.046 12.7 0.3 1.9 1 1 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.1 EMG46878.1 - 0.014 15.0 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EMG46878.1 - 0.016 14.6 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Dynamin_N PF00350.18 EMG46878.1 - 0.024 14.4 8.0 2.6 7.8 0.0 3.4 2 1 1 3 3 3 0 Dynamin family AAA_10 PF12846.2 EMG46878.1 - 0.055 12.9 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 EMG46878.1 - 0.063 13.5 0.7 0.24 11.7 0.0 2.2 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.17 EMG46878.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.1 EMG46878.1 - 3.3 8.0 22.3 2.5e+02 1.8 15.5 2.3 1 1 0 1 1 1 0 AAA domain Recep_L_domain PF01030.19 EMG46879.1 - 3.3e-07 30.2 6.0 0.0058 16.5 1.2 4.1 1 1 3 4 4 4 3 Receptor L domain DASH_Spc19 PF08287.6 EMG46880.1 - 7.7e-33 113.2 11.7 8.8e-33 113.0 8.1 1.0 1 0 0 1 1 1 1 Spc19 Blo-t-5 PF11642.3 EMG46880.1 - 0.01 15.5 0.2 0.022 14.5 0.2 1.5 1 0 0 1 1 1 0 Mite allergen Blo t 5 FlgN PF05130.7 EMG46880.1 - 0.14 12.3 5.5 0.16 12.1 0.8 2.1 2 0 0 2 2 2 0 FlgN protein Sas10_Utp3 PF04000.10 EMG46880.1 - 0.26 11.4 0.1 0.26 11.4 0.1 2.5 3 0 0 3 3 3 0 Sas10/Utp3/C1D family AAA_23 PF13476.1 EMG46880.1 - 0.38 11.0 9.8 0.5 10.6 6.8 1.2 1 0 0 1 1 1 0 AAA domain DUF4140 PF13600.1 EMG46880.1 - 0.38 11.2 4.0 1.7 9.1 0.1 2.8 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Sec8_exocyst PF04048.9 EMG46880.1 - 0.52 9.9 5.2 4.4 6.9 0.7 2.4 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain DUF3186 PF11382.3 EMG46880.1 - 0.65 9.0 2.9 2.1 7.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3186) V_ATPase_I PF01496.14 EMG46880.1 - 0.75 7.5 4.3 0.92 7.2 2.9 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 EMG46880.1 - 0.8 9.8 7.4 0.33 11.0 2.4 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 EMG46880.1 - 1 9.2 4.3 2.1 8.2 0.0 2.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF972 PF06156.8 EMG46880.1 - 1.5 9.2 5.9 1.5 9.1 1.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF972) TEX12 PF15219.1 EMG46880.1 - 2.7 8.0 5.7 2 8.4 2.0 2.0 1 1 1 2 2 2 0 Testis-expressed 12 Syntaxin-6_N PF09177.6 EMG46880.1 - 3.8 7.9 6.5 24 5.4 3.1 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF342 PF03961.8 EMG46880.1 - 5.1 5.3 7.7 3.1 6.1 3.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) bZIP_1 PF00170.16 EMG46880.1 - 5.1 7.1 14.0 1.2 9.1 0.8 3.2 3 0 0 3 3 3 0 bZIP transcription factor DUF3847 PF12958.2 EMG46880.1 - 5.4 6.8 8.5 3.3 7.5 0.5 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3847) BLOC1_2 PF10046.4 EMG46880.1 - 6.5 6.9 10.6 1.2 9.2 0.8 2.8 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1560 PF07597.6 EMG46881.1 - 0.053 13.5 0.0 2.3 8.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1560) NTR2 PF15458.1 EMG46881.1 - 0.069 12.3 13.9 0.73 9.0 3.7 2.7 1 1 1 2 2 2 0 Nineteen complex-related protein 2 HSF_DNA-bind PF00447.12 EMG46881.1 - 0.12 12.6 1.6 0.47 10.6 0.1 2.5 2 0 0 2 2 2 0 HSF-type DNA-binding NblA PF04485.7 EMG46881.1 - 0.26 11.1 7.3 28 4.6 0.0 4.9 3 1 2 5 5 5 0 Phycobilisome degradation protein nblA Matrilin_ccoil PF10393.4 EMG46881.1 - 1 8.8 14.3 7.6 5.9 0.1 4.9 3 1 2 5 5 5 0 Trimeric coiled-coil oligomerisation domain of matrilin Rnk_N PF14760.1 EMG46881.1 - 6.9 6.8 12.8 95 3.1 0.1 5.2 4 1 1 5 5 5 0 Rnk N-terminus VHS PF00790.14 EMG46882.1 - 1.9e-41 140.9 0.0 5.8e-41 139.4 0.0 1.8 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.15 EMG46882.1 - 2e-19 70.0 1.2 5.4e-19 68.6 0.8 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.9 EMG46882.1 - 3.4e-11 42.9 1.5 1.3e-10 41.1 0.3 2.6 3 1 1 4 4 4 1 GAT domain RmuC PF02646.11 EMG46882.1 - 0.00041 19.2 0.8 0.00064 18.6 0.5 1.3 1 0 0 1 1 1 1 RmuC family DUF4112 PF13430.1 EMG46884.1 - 2.3e-35 120.6 0.3 3e-35 120.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Coq4 PF05019.8 EMG46885.1 - 1.3e-98 328.3 0.0 1.7e-98 327.9 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 PXA PF02194.10 EMG46886.1 - 3e-07 30.1 7.9 3e-07 30.1 5.5 3.4 3 1 0 3 3 3 1 PXA domain Nexin_C PF08628.7 EMG46886.1 - 0.096 12.7 1.8 0.53 10.3 0.1 2.7 2 0 0 2 2 2 0 Sorting nexin C terminal BPL_LplA_LipB PF03099.14 EMG46887.1 - 4.9e-11 42.7 0.1 7.3e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Glyco_hydro_108 PF05838.7 EMG46887.1 - 0.043 13.9 0.0 0.092 12.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase 108 zf-DHHC PF01529.15 EMG46888.1 - 1.2e-34 119.2 16.2 1.2e-34 119.2 11.2 3.2 2 1 1 3 3 3 1 DHHC palmitoyltransferase DUF2247 PF10004.4 EMG46889.1 - 0.026 14.2 2.4 1.6 8.4 0.5 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) Colicin PF01024.14 EMG46889.1 - 0.06 12.9 0.6 0.13 11.8 0.4 1.5 1 0 0 1 1 1 0 Colicin pore forming domain CybS PF05328.7 EMG46890.1 - 7.3e-53 177.7 0.0 1e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 EMG46890.1 - 0.13 12.0 1.2 3.4 7.5 0.8 2.2 1 1 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit FHA PF00498.21 EMG46892.1 - 3e-14 52.8 1.0 1.1e-13 51.0 0.0 2.6 3 0 0 3 3 3 1 FHA domain Sen15 PF09631.5 EMG46893.1 - 1.3e-26 92.7 0.2 1.5e-26 92.5 0.1 1.0 1 0 0 1 1 1 1 Sen15 protein Globin PF00042.17 EMG46894.1 - 5.4e-06 26.7 0.1 0.00013 22.2 0.0 3.0 3 1 0 3 3 3 1 Globin Ima1_N PF09779.4 EMG46894.1 - 2.5 8.6 8.1 7.3 7.0 0.0 3.1 2 1 0 2 2 2 0 Ima1 N-terminal domain DASH_Dad2 PF08654.5 EMG46895.1 - 0.0065 16.4 0.0 0.0072 16.3 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 PUF PF00806.14 EMG46897.1 - 8.8e-29 97.3 6.9 0.0025 17.2 0.0 8.7 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat EXOSC1 PF10447.4 EMG46898.1 - 3.7e-30 103.7 0.1 7.9e-30 102.6 0.1 1.6 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 EMG46898.1 - 0.047 13.7 2.1 0.55 10.3 0.1 2.6 2 1 0 2 2 2 0 S1 RNA binding domain tRNA-synt_2 PF00152.15 EMG46899.1 - 7.5e-111 370.1 0.0 1e-110 369.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EMG46899.1 - 1.1e-07 31.6 0.0 3.1e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 EMG46899.1 - 3.7e-05 23.3 0.0 0.2 11.2 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 EMG46899.1 - 0.041 13.0 0.0 0.16 11.1 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) NUDIX PF00293.23 EMG46900.1 - 9.5e-14 51.1 0.0 1.3e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Glyco_transf_15 PF01793.11 EMG46901.1 - 4.9e-121 403.7 18.4 6.4e-121 403.3 12.8 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF4014 PF13198.1 EMG46901.1 - 0.05 14.0 1.1 0.05 14.0 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) zf-AN1 PF01428.11 EMG46902.1 - 7.9e-11 41.6 12.2 1.3e-10 41.0 8.4 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.10 EMG46902.1 - 0.16 12.2 4.8 0.3 11.3 3.3 1.4 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain UBN2_3 PF14244.1 EMG46903.1 - 0.08 12.5 0.3 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Elongin_A PF06881.6 EMG46905.1 - 3.4e-21 75.6 2.2 6.1e-21 74.8 1.5 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Apolipoprotein PF01442.13 EMG46905.1 - 0.013 14.9 0.0 0.025 14.1 0.0 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain CRAL_TRIO PF00650.15 EMG46906.1 - 1.2e-21 76.8 0.0 2e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMG46906.1 - 3.9e-13 49.3 1.7 1.1e-12 47.8 1.2 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Glyco_hydro_20 PF00728.17 EMG46907.1 - 1.5e-88 297.3 0.0 1.9e-88 297.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EMG46907.1 - 1.1e-20 74.5 0.0 2.6e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EMG46907.1 - 8.3e-05 23.1 0.0 0.00014 22.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 HORMA PF02301.13 EMG46908.1 - 2.5e-42 144.7 0.9 2.8e-42 144.5 0.6 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 EMG46908.1 - 0.024 14.0 0.2 0.041 13.2 0.1 1.4 2 0 0 2 2 2 0 Autophagy-related protein 13 RAB3GAP2_C PF14656.1 EMG46908.1 - 0.031 12.4 0.1 0.036 12.2 0.1 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Alg14 PF08660.6 EMG46908.1 - 0.12 12.4 0.1 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like PPTA PF01239.17 EMG46909.1 - 3.1e-39 130.6 19.7 7.9e-09 34.4 0.1 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF310 PF03750.8 EMG46909.1 - 2.3 8.4 5.9 3.1 8.0 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF310) DUF4246 PF14033.1 EMG46910.1 - 2.8e-141 471.5 4.6 9.7e-141 469.7 3.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EMG46910.1 - 0.011 15.9 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Porin_3 PF01459.17 EMG46912.1 - 2.3e-64 217.3 6.7 2.6e-64 217.1 4.6 1.0 1 0 0 1 1 1 1 Eukaryotic porin RRM_1 PF00076.17 EMG46913.1 - 2.3e-16 59.1 0.1 4.5e-16 58.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG46913.1 - 3.4e-10 39.7 0.1 5.7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG46913.1 - 4.4e-05 23.2 0.1 7.5e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.9 EMG46913.1 - 5.8 4.8 9.1 6.6 4.6 6.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Macro_2 PF14519.1 EMG46915.1 - 4.1e-14 52.3 3.0 1.1e-13 50.9 2.1 1.7 1 1 0 1 1 1 1 Macro-like domain NUDIX PF00293.23 EMG46915.1 - 1.5e-08 34.3 0.0 2.8e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Lip_prot_lig_C PF10437.4 EMG46915.1 - 0.0027 17.3 0.1 0.012 15.3 0.0 2.1 1 0 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus Macro PF01661.16 EMG46915.1 - 0.048 13.5 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Macro domain BOP1NT PF08145.7 EMG46916.1 - 1.3e-104 349.6 9.0 1.3e-104 349.6 6.3 1.7 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.27 EMG46916.1 - 3.6e-32 109.0 5.6 1.4e-10 40.6 0.2 7.9 7 1 0 7 7 7 6 WD domain, G-beta repeat Daxx PF03344.10 EMG46916.1 - 2.3 6.6 24.3 0.26 9.7 12.5 2.0 2 0 0 2 2 2 0 Daxx Family PGAP1 PF07819.8 EMG46917.1 - 1.6e-44 152.1 0.0 1.4e-42 145.8 0.0 2.1 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EMG46917.1 - 8.7e-11 41.7 0.0 3.1e-10 39.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMG46917.1 - 5e-09 36.3 0.0 6.9e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMG46917.1 - 7.3e-08 32.2 0.0 8.3e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 EMG46917.1 - 2.1e-05 23.8 0.0 4.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF2305 PF10230.4 EMG46917.1 - 2.7e-05 23.7 0.0 4.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Esterase PF00756.15 EMG46917.1 - 0.0012 18.3 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DUF2974 PF11187.3 EMG46917.1 - 0.0026 17.1 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) BAAT_C PF08840.6 EMG46917.1 - 0.0039 16.9 0.0 0.0064 16.2 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 EMG46917.1 - 0.0052 16.2 0.0 0.01 15.3 0.0 1.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.8 EMG46917.1 - 0.01 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase LCAT PF02450.10 EMG46917.1 - 0.011 14.7 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 EMG46917.1 - 0.05 12.9 0.0 0.073 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 2) Lipase_3 PF01764.20 EMG46917.1 - 0.053 13.1 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.6 EMG46917.1 - 0.059 12.4 0.0 3.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DLH PF01738.13 EMG46917.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_8 PF06259.7 EMG46917.1 - 0.15 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase Septin PF00735.13 EMG46918.1 - 1.1e-120 401.9 4.2 1.1e-120 401.9 2.9 1.7 2 0 0 2 2 2 1 Septin DUF258 PF03193.11 EMG46918.1 - 0.0011 18.1 0.0 0.0024 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EMG46918.1 - 0.0017 18.3 0.0 0.0044 16.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMG46918.1 - 0.0026 17.2 3.5 0.017 14.5 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EMG46918.1 - 0.025 14.5 0.4 3.7 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 EMG46918.1 - 0.031 14.5 2.4 0.18 12.0 0.0 2.5 2 1 0 2 2 2 0 ABC transporter AIG1 PF04548.11 EMG46918.1 - 0.052 12.6 0.1 0.052 12.6 0.0 2.1 2 0 0 2 2 2 0 AIG1 family AAA_24 PF13479.1 EMG46918.1 - 0.057 12.9 0.7 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EMG46918.1 - 0.06 12.8 0.2 0.24 10.9 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EMG46918.1 - 0.094 12.8 0.5 0.44 10.6 0.0 2.4 2 2 0 2 2 2 0 AAA domain DUF2852 PF11014.3 EMG46918.1 - 4.6 7.2 8.6 6.6 6.7 4.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2852) UPF0121 PF03661.8 EMG46919.1 - 5e-10 38.9 5.1 6.1e-10 38.7 3.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DUF594 PF04578.8 EMG46919.1 - 0.061 12.7 0.0 0.19 11.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function, DUF594 BLVR PF06375.6 EMG46920.1 - 0.0082 15.9 1.3 0.011 15.5 0.9 1.2 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) DUF2240 PF09999.4 EMG46920.1 - 0.02 14.3 0.5 0.11 11.8 0.3 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) Proteasom_Rpn13 PF04683.8 EMG46921.1 - 6e-24 83.9 0.0 1e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor UPF0149 PF03695.8 EMG46921.1 - 0.25 11.2 2.9 0.51 10.2 1.8 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) CinA PF02464.12 EMG46922.1 - 2e-29 102.0 0.0 3.1e-22 78.6 0.0 2.0 2 0 0 2 2 2 2 Competence-damaged protein AMP-binding PF00501.23 EMG46924.1 - 3.5e-90 302.3 0.0 4.3e-90 302.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMG46924.1 - 7.9e-20 71.5 1.2 3e-19 69.7 0.6 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Mannosyl_trans2 PF04188.8 EMG46925.1 - 1.2e-36 126.5 20.6 1.4e-26 93.3 5.7 2.2 1 1 1 2 2 2 2 Mannosyltransferase (PIG-V)) DUF3445 PF11927.3 EMG46926.1 - 3.9e-72 242.6 0.0 5.5e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Histone PF00125.19 EMG46927.1 - 3.5e-32 110.3 0.3 4.4e-32 110.0 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EMG46927.1 - 1.5e-06 28.2 0.0 2.1e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EMG46927.1 - 0.0066 16.4 0.1 0.0098 15.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HSP70 PF00012.15 EMG46928.1 - 2.5e-10 38.9 11.9 2.8e-10 38.7 8.2 1.0 1 0 0 1 1 1 1 Hsp70 protein Cnd1_N PF12922.2 EMG46928.1 - 0.86 9.2 4.7 1 8.9 3.2 1.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term DUF3605 PF12239.3 EMG46929.1 - 4.5e-46 156.5 10.9 5.7e-46 156.2 7.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) adh_short PF00106.20 EMG46930.1 - 8.8e-25 87.5 0.1 1.2e-24 87.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMG46930.1 - 6.2e-12 45.8 0.1 7e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMG46930.1 - 1.1e-09 38.2 0.1 1.6e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 EMG46930.1 - 2.4e-05 24.2 0.3 0.00012 22.0 0.1 2.0 2 0 0 2 2 2 1 TrkA-N domain F420_oxidored PF03807.12 EMG46930.1 - 0.0024 18.2 0.3 0.0046 17.3 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 EMG46930.1 - 0.0065 15.4 0.1 0.011 14.7 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EMG46930.1 - 0.0072 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.7 EMG46930.1 - 0.06 12.2 0.1 0.21 10.4 0.0 2.0 1 1 0 1 1 1 0 Male sterility protein PQ-loop PF04193.9 EMG46931.1 - 1.3e-11 43.8 14.2 6.9e-09 35.1 1.7 2.9 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.13 EMG46931.1 - 0.055 13.9 0.2 0.055 13.9 0.1 2.9 2 1 0 3 3 3 0 ER lumen protein retaining receptor zf-C2H2 PF00096.21 EMG46932.1 - 3.9e-07 30.0 2.8 0.0033 17.6 0.3 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMG46932.1 - 1.3e-05 25.1 2.4 0.12 12.7 0.6 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger His_Phos_1 PF00300.17 EMG46933.1 - 1.7e-38 132.2 0.0 2.1e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ACDC PF14733.1 EMG46934.1 - 0.15 12.1 0.7 0.23 11.6 0.5 1.2 1 0 0 1 1 1 0 AP2-coincident C-terminal adh_short PF00106.20 EMG46935.1 - 7.3e-29 100.8 0.1 1.1e-28 100.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMG46935.1 - 3.3e-15 56.5 0.0 3.9e-15 56.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMG46935.1 - 1.8e-12 47.3 0.1 2.8e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMG46935.1 - 1.3e-06 28.5 0.1 1.7e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EMG46935.1 - 1.4e-06 28.3 0.1 2.3e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_18 PF12847.2 EMG46935.1 - 4.2e-05 24.0 0.0 7.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 EMG46935.1 - 0.00062 18.5 0.0 0.00094 17.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EMG46935.1 - 0.004 16.4 0.6 0.0065 15.7 0.4 1.3 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 EMG46935.1 - 0.0044 16.0 0.2 0.0068 15.4 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EMG46935.1 - 0.088 11.6 0.1 0.13 11.0 0.1 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EMG46935.1 - 0.098 12.7 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 EMG46936.1 - 4.5e-26 91.7 0.5 6.1e-26 91.3 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMG46936.1 - 3.1e-24 86.0 0.1 3.7e-24 85.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMG46936.1 - 1.2e-13 51.1 0.1 1.9e-13 50.4 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EMG46936.1 - 0.008 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 EMG46936.1 - 0.03 13.2 0.2 0.045 12.6 0.2 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 EMG46936.1 - 0.085 12.2 0.1 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RRM_1 PF00076.17 EMG46938.1 - 4.9e-54 179.8 0.8 5.1e-15 54.8 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG46938.1 - 1.9e-41 139.8 0.2 1.3e-11 44.3 0.0 5.0 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG46938.1 - 1.6e-14 53.4 1.1 2.6e-06 27.1 0.2 4.9 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CENP-T PF15511.1 EMG46938.1 - 0.00018 20.8 18.1 0.00018 20.8 12.5 2.3 2 0 0 2 2 2 2 Centromere kinetochore component CENP-T Metallophos PF00149.23 EMG46939.1 - 6.7e-40 136.6 0.2 8.8e-40 136.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMG46939.1 - 0.0026 17.5 0.0 0.0043 16.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_S18 PF01084.15 EMG46940.1 - 6.5e-16 57.9 0.0 1.6e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S18 IATP PF04568.7 EMG46941.1 - 2.5e-16 59.5 2.7 2.8e-16 59.3 1.8 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Fib_alpha PF08702.5 EMG46941.1 - 0.0056 16.7 0.6 0.0056 16.7 0.4 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF4640 PF15480.1 EMG46941.1 - 0.012 15.2 1.6 0.013 15.0 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4640) DUF641 PF04859.7 EMG46941.1 - 0.022 14.5 1.6 0.025 14.3 1.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) PspB PF06667.7 EMG46941.1 - 0.028 14.3 2.5 0.037 13.9 1.7 1.2 1 0 0 1 1 1 0 Phage shock protein B DUF1664 PF07889.7 EMG46941.1 - 0.041 13.6 1.2 0.05 13.3 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Tektin PF03148.9 EMG46941.1 - 0.046 12.2 4.8 0.049 12.1 3.3 1.0 1 0 0 1 1 1 0 Tektin family PilO PF04350.8 EMG46941.1 - 0.063 13.1 6.4 0.084 12.7 4.5 1.1 1 0 0 1 1 1 0 Pilus assembly protein, PilO DUF4407 PF14362.1 EMG46941.1 - 0.095 11.6 4.2 0.1 11.5 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.4 EMG46941.1 - 0.14 11.0 2.8 0.15 11.0 1.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CASP_C PF08172.7 EMG46941.1 - 0.16 10.9 4.6 0.24 10.3 3.2 1.3 1 0 0 1 1 1 0 CASP C terminal Glutaredoxin2_C PF04399.8 EMG46941.1 - 0.6 9.7 4.7 7.4 6.1 3.7 1.9 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain IncA PF04156.9 EMG46941.1 - 0.99 8.9 8.2 1.3 8.5 5.7 1.2 1 1 0 1 1 1 0 IncA protein DUF4140 PF13600.1 EMG46941.1 - 2.7 8.4 5.3 3.7 8.0 3.7 1.5 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 EMG46941.1 - 4 6.9 9.7 4.6 6.8 6.4 1.4 1 1 0 1 1 1 0 Septum formation initiator UIM PF02809.15 EMG46942.1 - 0.0084 15.5 1.5 0.03 13.8 1.0 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif CLTH PF10607.4 EMG46943.1 - 1.9e-27 95.7 2.8 1.9e-27 95.7 1.9 2.9 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EMG46943.1 - 2.9e-09 36.4 0.1 5.1e-08 32.5 0.1 2.9 1 1 0 1 1 1 1 RING-type zinc-finger Phasin PF05597.6 EMG46943.1 - 0.0044 16.7 1.0 0.011 15.5 0.7 1.6 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Orexin_rec2 PF03827.8 EMG46943.1 - 0.013 15.5 0.7 0.048 13.7 0.5 2.0 1 0 0 1 1 1 0 Orexin receptor type 2 PyrI_C PF02748.10 EMG46943.1 - 0.27 10.6 3.1 0.35 10.3 1.1 2.0 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain AATF-Che1 PF13339.1 EMG46943.1 - 0.58 10.3 7.4 0.76 9.9 3.5 2.3 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Peptidase_M1 PF01433.15 EMG46944.1 - 3.4e-133 444.5 0.2 5.1e-133 443.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EMG46944.1 - 3.8e-90 302.4 0.2 8e-90 301.3 0.1 1.6 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EMG46944.1 - 2.3e-18 66.4 0.0 7.1e-18 64.8 0.0 1.8 2 0 0 2 2 2 1 Peptidase MA superfamily Lipocalin_6 PF13944.1 EMG46944.1 - 0.018 15.1 0.6 0.04 14.0 0.4 1.6 1 0 0 1 1 1 0 Lipocalin-like domain DUF1025 PF06262.6 EMG46944.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase SprT-like PF10263.4 EMG46944.1 - 0.17 11.5 0.0 0.56 9.8 0.0 1.8 2 0 0 2 2 2 0 SprT-like family Rotamase PF00639.16 EMG46945.1 - 1.7e-24 86.3 0.0 2.4e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EMG46945.1 - 1.7e-20 73.3 0.0 2.2e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EMG46945.1 - 1.1e-07 31.5 1.3 2.4e-07 30.4 0.9 1.6 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 EMG46945.1 - 1.1e-05 26.0 0.0 1.7e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain ADK PF00406.17 EMG46946.1 - 1.9e-45 154.4 0.1 2.8e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EMG46946.1 - 1.7e-08 34.8 0.0 2.9e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMG46946.1 - 4.8e-08 32.9 0.0 9.9e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMG46946.1 - 2.4e-06 28.3 0.0 3.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EMG46946.1 - 0.0012 18.2 0.4 1.1 8.6 0.0 2.4 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.7 EMG46946.1 - 0.0027 16.8 0.0 0.0043 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin CENP-N PF05238.8 EMG46947.1 - 7.1e-107 357.9 3.5 8.3e-107 357.6 2.4 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like Vps16_N PF04841.8 EMG46948.1 - 3.9e-48 163.9 3.9 1.1e-22 80.2 0.0 3.3 2 1 0 2 2 2 2 Vps16, N-terminal region Vps16_C PF04840.7 EMG46948.1 - 1.4e-35 122.7 8.8 5.7e-35 120.7 6.1 1.9 1 1 0 1 1 1 1 Vps16, C-terminal region AHS1 PF02682.11 EMG46949.1 - 0.00036 20.0 0.0 0.00057 19.4 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 AHS1 PF02682.11 EMG46950.1 - 8e-25 87.4 0.0 9.4e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 AHS2 PF02626.10 EMG46951.1 - 5.2e-68 229.2 0.0 5.8e-68 229.1 0.0 1.0 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 SSF PF00474.12 EMG46952.1 - 2.6e-05 23.0 1.3 2.6e-05 23.0 0.9 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family YtpI PF14007.1 EMG46952.1 - 0.4 10.6 3.0 0.66 9.9 2.1 1.4 1 0 0 1 1 1 0 YtpI-like protein AdoMet_MTase PF07757.8 EMG46953.1 - 5.6e-41 139.1 0.2 9.9e-41 138.3 0.1 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 EMG46953.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SHNi-TPR PF10516.4 EMG46954.1 - 1.8e-17 62.2 0.8 4.5e-17 60.9 0.4 1.8 2 0 0 2 2 2 1 SHNi-TPR TPR_11 PF13414.1 EMG46954.1 - 5.4e-05 22.7 1.3 0.039 13.6 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 EMG46954.1 - 0.019 14.9 3.6 0.021 14.7 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3144 PF11342.3 EMG46954.1 - 0.03 14.4 0.8 0.08 13.0 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) TPR_2 PF07719.12 EMG46954.1 - 0.15 12.0 3.2 1.4 9.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ICL PF00463.16 EMG46955.1 - 3.1e-301 999.1 2.3 3.5e-301 998.9 1.6 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EMG46955.1 - 7.8e-11 41.6 0.0 1.7e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Pkinase PF00069.20 EMG46957.1 - 6.8e-77 258.1 0.0 8.6e-77 257.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG46957.1 - 2.7e-36 124.9 0.0 4e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG46957.1 - 0.0044 16.0 0.2 0.0093 14.9 0.1 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMG46957.1 - 0.024 13.7 0.1 0.05 12.6 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CNH PF00780.17 EMG46959.1 - 4.3e-14 52.5 0.0 9.9e-14 51.4 0.0 1.6 1 1 0 1 1 1 1 CNH domain PH_5 PF15405.1 EMG46959.1 - 1.9e-09 37.5 0.0 6.7e-09 35.7 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EMG46959.1 - 1.7e-06 28.1 0.1 5e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.15 EMG46959.1 - 0.00067 19.5 2.0 0.0012 18.7 1.4 1.4 1 0 0 1 1 1 1 RhoGEF domain OGG_N PF07934.7 EMG46959.1 - 0.012 15.5 0.0 0.078 12.9 0.0 2.4 1 0 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain Abhydrolase_6 PF12697.2 EMG46960.1 - 1.6e-22 80.5 0.0 2.3e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMG46960.1 - 5.3e-17 61.9 0.0 8.8e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMG46960.1 - 5.6e-15 55.5 0.0 1.2e-14 54.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2305 PF10230.4 EMG46960.1 - 6.6e-10 38.8 0.2 1.1e-09 38.0 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 EMG46960.1 - 1e-06 28.4 0.3 4.9e-06 26.2 0.2 2.0 1 1 0 1 1 1 1 PGAP1-like protein Ser_hydrolase PF06821.8 EMG46960.1 - 2.8e-06 27.0 0.0 1e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_2 PF02230.11 EMG46960.1 - 2.9e-06 26.8 0.1 0.02 14.3 0.0 2.9 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Esterase PF00756.15 EMG46960.1 - 6.7e-05 22.4 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 EMG46960.1 - 0.00044 19.9 0.0 0.00089 18.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EMG46960.1 - 0.00061 20.0 0.0 0.0041 17.3 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain DUF676 PF05057.9 EMG46960.1 - 0.001 18.3 2.4 0.002 17.4 0.5 2.2 2 1 0 2 2 2 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.3 EMG46960.1 - 0.0093 15.7 0.0 0.18 11.6 0.0 2.3 2 0 0 2 2 2 1 Putative lysophospholipase LCAT PF02450.10 EMG46960.1 - 0.017 14.0 0.0 0.1 11.5 0.0 2.1 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase DUF1057 PF06342.7 EMG46960.1 - 0.034 12.9 0.0 0.071 11.9 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Peptidase_S9 PF00326.16 EMG46960.1 - 0.037 13.2 0.0 5.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Lipase_3 PF01764.20 EMG46960.1 - 0.041 13.4 0.2 0.22 11.1 0.0 2.1 2 1 0 3 3 3 0 Lipase (class 3) DUF900 PF05990.7 EMG46960.1 - 0.043 13.1 0.0 0.34 10.2 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Chlorophyllase2 PF12740.2 EMG46960.1 - 0.078 11.8 0.0 0.15 10.8 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme DLH PF01738.13 EMG46960.1 - 0.19 10.9 0.0 1.8 7.8 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family E1-E2_ATPase PF00122.15 EMG46961.1 - 6.8e-25 87.4 1.2 6.8e-25 87.4 0.8 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EMG46961.1 - 3.2e-12 47.3 0.0 4.2e-11 43.6 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMG46961.1 - 2.2e-09 37.7 0.0 8.5e-09 35.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMG46961.1 - 6.9e-07 29.1 0.0 1.7e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMG46961.1 - 0.00089 18.9 0.1 0.0028 17.2 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase MHYT PF03707.11 EMG46961.1 - 1.6 8.9 7.0 1 9.5 0.5 3.2 3 0 0 3 3 3 0 Bacterial signalling protein N terminal repeat MIP-T3 PF10243.4 EMG46962.1 - 1 7.7 40.1 1.5 7.2 27.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 ATP-synt_ab PF00006.20 EMG46963.1 - 4.6e-69 232.1 0.0 6.8e-69 231.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EMG46963.1 - 9.5e-26 90.5 0.2 2.9e-25 88.9 0.2 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EMG46963.1 - 6.8e-18 64.6 0.7 1.6e-17 63.4 0.5 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EMG46963.1 - 0.0043 16.9 0.6 0.0093 15.8 0.4 1.6 1 0 0 1 1 1 1 HAS barrel domain AAA_25 PF13481.1 EMG46963.1 - 0.027 13.8 0.1 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain SSF PF00474.12 EMG46965.1 - 9.9e-06 24.4 5.1 1e-05 24.3 3.6 1.0 1 0 0 1 1 1 1 Sodium:solute symporter family YtpI PF14007.1 EMG46965.1 - 0.14 12.0 1.6 0.19 11.6 1.1 1.3 1 0 0 1 1 1 0 YtpI-like protein BPD_transp_2 PF02653.11 EMG46965.1 - 0.18 10.7 5.5 0.18 10.7 3.8 1.0 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component SdpI PF13630.1 EMG46965.1 - 9.2 6.0 9.1 35 4.1 6.3 1.8 1 1 1 2 2 2 0 SdpI/YhfL protein family DUF4083 PF13314.1 EMG46965.1 - 9.6 6.1 7.8 9.3 6.1 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) FGGY_N PF00370.16 EMG46966.1 - 3.6e-19 69.0 0.0 1.9e-11 43.7 0.0 3.2 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EMG46966.1 - 7.2e-12 45.3 0.0 1.6e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain zf-rbx1 PF12678.2 EMG46967.1 - 0.085 12.9 3.2 0.19 11.8 2.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger RAB3GAP2_N PF14655.1 EMG46967.1 - 0.15 11.0 0.4 0.71 8.8 0.0 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus zf-RING_2 PF13639.1 EMG46967.1 - 0.73 9.7 7.3 2 8.3 5.1 1.8 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 EMG46967.1 - 0.76 9.8 8.7 1.9 8.6 6.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) 2-Hacid_dh_C PF02826.14 EMG46968.1 - 1.8e-37 128.2 0.0 2.7e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMG46968.1 - 9.5e-14 51.0 0.0 1.1e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMG46968.1 - 0.00096 19.0 0.0 0.0033 17.2 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EMG46968.1 - 0.0059 15.9 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ApbA PF02558.11 EMG46968.1 - 0.013 14.9 0.1 0.033 13.6 0.1 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 EMG46968.1 - 0.016 15.5 0.0 0.04 14.3 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 EMG46968.1 - 0.083 13.4 0.2 0.26 11.8 0.1 1.8 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.1 EMG46968.1 - 0.095 12.9 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding PUF PF00806.14 EMG46969.1 - 1.5e-62 203.7 17.1 9.2e-08 31.1 0.3 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat BRAP2 PF07576.7 EMG46970.1 - 8.6e-05 22.0 0.2 0.00025 20.5 0.0 1.8 2 0 0 2 2 2 1 BRCA1-associated protein 2 RRM_5 PF13893.1 EMG46970.1 - 0.00021 21.0 1.4 0.071 12.9 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMG46970.1 - 0.034 13.7 0.1 1.8 8.2 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1938 PF09153.5 EMG46970.1 - 0.04 13.7 0.2 0.34 10.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1938) WD40 PF00400.27 EMG46971.1 - 4.4e-08 32.6 4.6 0.005 16.6 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat TPR_11 PF13414.1 EMG46972.1 - 2.5e-29 100.6 30.2 3.1e-11 42.7 0.3 8.0 6 2 1 8 8 8 5 TPR repeat TPR_2 PF07719.12 EMG46972.1 - 3.7e-29 98.2 24.8 5.9e-05 22.6 0.1 11.4 12 0 0 12 12 12 6 Tetratricopeptide repeat Apc3 PF12895.2 EMG46972.1 - 7.8e-27 93.2 16.4 8.5e-19 67.4 0.0 5.8 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EMG46972.1 - 1.6e-21 74.8 27.3 2.1e-06 27.1 0.1 10.2 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMG46972.1 - 8.9e-21 72.5 1.5 0.042 14.4 0.0 10.1 6 2 5 11 11 11 4 Tetratricopeptide repeat TPR_12 PF13424.1 EMG46972.1 - 2.3e-20 72.2 20.1 2.5e-09 36.9 0.2 8.5 7 2 3 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.1 EMG46972.1 - 1.1e-19 70.5 1.5 9.6e-05 22.9 0.0 7.0 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EMG46972.1 - 2.6e-18 64.3 12.7 4.3e-05 23.0 0.1 9.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMG46972.1 - 2.9e-15 55.0 9.9 0.012 15.7 0.0 9.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMG46972.1 - 5.5e-13 49.0 7.3 0.062 13.6 0.1 8.2 6 2 2 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMG46972.1 - 3.7e-11 41.9 8.7 0.23 11.3 0.0 7.7 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_10 PF13374.1 EMG46972.1 - 1e-10 41.1 1.3 0.25 11.3 0.1 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 EMG46972.1 - 2.1e-08 33.5 0.2 0.0016 17.5 0.0 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMG46972.1 - 3.3e-08 33.4 0.8 14 6.4 0.0 6.9 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 EMG46972.1 - 1.9e-05 24.4 1.2 0.017 14.9 0.0 4.3 4 1 1 5 5 4 1 Tetratricopeptide repeat Coatomer_E PF04733.9 EMG46972.1 - 0.001 18.3 2.3 1.2 8.2 0.0 3.7 3 1 1 4 4 4 2 Coatomer epsilon subunit MIT PF04212.13 EMG46972.1 - 0.61 9.9 8.5 2.2 8.2 0.0 4.5 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain WD40 PF00400.27 EMG46973.1 - 1.1e-35 120.2 1.7 9.1e-10 38.0 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EMG46973.1 - 1.7e-06 27.0 2.7 0.19 10.4 0.5 4.0 1 1 2 3 3 3 3 Nup133 N terminal like Nup160 PF11715.3 EMG46973.1 - 3.3e-05 22.2 0.1 0.002 16.3 0.0 2.3 2 1 0 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EMG46973.1 - 5.1e-05 23.0 0.9 0.52 10.0 0.2 3.9 2 1 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region TAF1D PF15333.1 EMG46973.1 - 0.01 15.6 1.3 0.017 14.9 0.9 1.3 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D CRT10 PF08728.5 EMG46973.1 - 0.017 13.1 0.1 0.07 11.1 0.0 2.1 1 1 1 2 2 2 0 CRT10 AlaDh_PNT_N PF05222.10 EMG46974.1 - 5.5e-30 104.1 0.0 8e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EMG46974.1 - 2.5e-22 79.2 0.0 3.4e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AA_permease PF00324.16 EMG46975.1 - 1.5e-49 168.6 10.9 1.6e-49 168.5 7.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG46975.1 - 9.5e-13 47.4 10.8 1.1e-12 47.2 7.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1049 PF06305.6 EMG46975.1 - 0.48 9.9 2.6 3 7.3 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) AA_kinase PF00696.23 EMG46977.1 - 1.6e-41 142.4 0.0 2.5e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 EMG46977.1 - 2.2e-10 39.8 2.3 2.2e-06 27.0 0.2 3.1 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.1 EMG46977.1 - 2e-07 30.3 2.4 8.9e-06 25.1 0.3 2.6 2 0 0 2 2 2 2 ACT domain TetR_C_5 PF08360.6 EMG46977.1 - 0.041 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 QacR-like protein, C-terminal region ACT_4 PF13291.1 EMG46977.1 - 0.26 11.6 8.1 0.95 9.8 0.1 3.4 3 1 0 3 3 3 0 ACT domain BAR_2 PF10455.4 EMG46978.1 - 2e-61 207.4 9.4 3.2e-61 206.7 6.6 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EMG46978.1 - 1.6e-14 53.9 4.9 7.5e-14 51.7 3.4 1.9 1 1 0 1 1 1 1 BAR domain DUF310 PF03750.8 EMG46978.1 - 0.00014 22.0 2.5 0.0023 18.0 0.2 2.7 2 2 0 2 2 2 1 Protein of unknown function (DUF310) Arfaptin PF06456.8 EMG46978.1 - 0.0033 16.8 4.6 0.041 13.2 0.2 2.9 1 1 1 3 3 3 1 Arfaptin-like domain APG17 PF04108.7 EMG46978.1 - 0.011 14.5 0.3 0.011 14.5 0.2 2.7 2 1 1 3 3 3 0 Autophagy protein Apg17 IFT46_B_C PF12317.3 EMG46978.1 - 0.73 9.1 6.4 2.5 7.4 0.7 2.4 2 1 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal GLYCAM-1 PF05242.6 EMG46978.1 - 1.2 9.0 5.5 1.3 8.9 1.0 2.8 2 2 0 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Prominin PF05478.6 EMG46978.1 - 1.7 6.0 9.3 0.1 10.1 1.2 2.3 2 1 0 2 2 2 0 Prominin Laminin_II PF06009.7 EMG46978.1 - 1.9 8.2 11.1 2.2 8.0 0.1 3.7 3 1 0 3 3 3 0 Laminin Domain II Aminotran_1_2 PF00155.16 EMG46979.1 - 2.2e-24 86.1 0.0 3.2e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EMG46979.1 - 0.027 13.0 0.0 0.13 10.8 0.0 1.8 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase DNA_ligase_aden PF01653.13 EMG46979.1 - 0.048 12.5 0.0 0.078 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain Tubulin PF00091.20 EMG46980.1 - 3.5e-76 255.7 0.6 8e-76 254.6 0.4 1.6 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMG46980.1 - 3.1e-20 72.4 0.2 5.4e-20 71.7 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain DUF4451 PF14616.1 EMG46980.1 - 0.00026 20.7 0.0 0.00066 19.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Misat_Tub_SegII PF10644.4 EMG46980.1 - 0.00046 20.2 3.8 0.1 12.6 2.6 2.6 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EMG46980.1 - 0.0028 17.1 0.0 0.013 14.9 0.0 2.2 1 1 0 1 1 1 1 Tubulin domain DUF4214 PF13946.1 EMG46980.1 - 0.074 12.7 0.6 1.2 8.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4214) Occludin_ELL PF07303.8 EMG46980.1 - 4.7 7.9 8.0 0.38 11.5 1.5 2.1 3 0 0 3 3 3 0 Occludin homology domain Cation_efflux PF01545.16 EMG46981.1 - 1e-17 64.1 6.0 1.5e-17 63.6 4.2 1.2 1 0 0 1 1 1 1 Cation efflux family SIS PF01380.17 EMG46982.1 - 5.5e-12 45.4 0.3 1.3e-11 44.2 0.2 1.6 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.1 EMG46982.1 - 0.0025 17.5 0.4 0.56 9.9 0.0 3.0 2 1 1 3 3 3 2 SIS domain UPF0118 PF01594.11 EMG46982.1 - 0.35 9.8 2.1 0.57 9.1 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF20 NAD_binding_1 PF00175.16 EMG46983.1 - 1.1e-30 106.3 0.0 1.7e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EMG46983.1 - 2.1e-28 98.3 0.0 3.2e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EMG46983.1 - 2.4e-05 24.2 0.0 0.002 18.0 0.0 2.2 1 1 0 2 2 2 2 Ferric reductase NAD binding domain Ofd1_CTDD PF10637.4 EMG46984.1 - 2.5e-101 338.3 0.6 1.5e-97 325.9 0.3 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EMG46984.1 - 7.9e-14 51.9 0.0 4.1e-13 49.6 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF946 PF06101.6 EMG46986.1 - 2.1e-11 42.5 3.3 4.6e-11 41.4 2.3 1.5 1 1 0 1 1 1 1 Plant protein of unknown function (DUF946) AA_permease PF00324.16 EMG46987.1 - 1e-49 169.2 10.9 1.1e-49 169.0 7.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG46987.1 - 6.8e-13 47.9 10.8 7.8e-13 47.7 7.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1049 PF06305.6 EMG46987.1 - 0.62 9.5 3.2 2.6 7.5 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF3384 PF11864.3 EMG46989.1 - 6.9e-74 248.9 17.2 2.1e-73 247.3 11.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 EMG46989.1 - 2.6e-55 186.7 1.7 2.6e-55 186.7 1.2 2.6 3 0 0 3 3 3 1 Rap/ran-GAP Tuberin PF03542.11 EMG46989.1 - 7.8e-22 77.8 0.3 2.2e-20 73.0 0.0 2.6 3 0 0 3 3 3 1 Tuberin GOLD_2 PF13897.1 EMG46989.1 - 0.059 13.5 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Candida_ALS PF05792.8 EMG46990.1 - 2.3e-16 59.5 49.0 2e-12 46.9 11.8 3.7 3 0 0 3 3 3 3 Candida agglutinin-like (ALS) Vps5 PF09325.5 EMG46993.1 - 4.7e-79 264.9 16.1 1.4e-78 263.4 11.1 1.8 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EMG46993.1 - 3.4e-22 78.3 3.0 3.5e-22 78.3 0.1 2.3 2 0 0 2 2 2 1 PX domain DUF4632 PF15451.1 EMG46993.1 - 0.56 10.1 2.7 1.6 8.7 1.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) DUF1664 PF07889.7 EMG46993.1 - 2.4 7.9 8.0 0.91 9.3 1.7 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 EMG46993.1 - 8.9 6.1 10.9 5.4 6.8 3.1 2.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Usp PF00582.21 EMG46995.1 - 6.6e-20 71.7 0.0 9.3e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Fibrillarin PF01269.12 EMG46996.1 - 4.1e-108 359.5 0.0 4.9e-108 359.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EMG46996.1 - 0.00027 20.5 0.1 0.00066 19.2 0.1 1.5 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EMG46996.1 - 0.042 13.3 0.0 0.11 12.0 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UMP1 PF05348.6 EMG46997.1 - 1.4e-31 109.1 0.0 1.7e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 GYF PF02213.11 EMG46998.1 - 2.6e-16 58.9 0.0 7.3e-16 57.4 0.0 1.8 1 0 0 1 1 1 1 GYF domain DUF4339 PF14237.1 EMG46998.1 - 0.0035 16.8 0.5 0.062 12.8 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4339) ACT_7 PF13840.1 EMG46999.1 - 3.5e-30 103.3 0.4 4.3e-16 58.1 0.1 2.5 2 0 0 2 2 2 2 ACT domain MOZART2 PF12926.2 EMG47000.1 - 0.15 11.6 0.7 0.28 10.8 0.1 1.7 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated UBA_4 PF14555.1 EMG47001.1 - 1.1e-11 44.0 0.2 1.1e-11 44.0 0.1 1.7 2 0 0 2 2 2 1 UBA-like domain UBX PF00789.15 EMG47001.1 - 8.7e-10 38.5 0.1 1.9e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.1 EMG47001.1 - 0.034 14.1 0.0 0.086 12.8 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like DAO PF01266.19 EMG47002.1 - 4.5e-51 173.8 0.0 1.9e-50 171.7 0.0 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMG47002.1 - 8.6e-12 44.6 0.0 1.6e-11 43.7 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EMG47002.1 - 1.1e-07 31.3 3.9 1.3e-06 27.8 2.7 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMG47002.1 - 5.5e-05 23.1 0.6 0.0029 17.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMG47002.1 - 0.00033 19.6 0.7 0.017 14.0 0.2 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 EMG47002.1 - 0.0013 17.2 0.3 0.0028 16.1 0.2 1.5 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EMG47002.1 - 0.0023 17.0 0.2 0.052 12.6 0.1 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EMG47002.1 - 0.016 14.2 0.4 0.042 12.8 0.3 1.7 1 1 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.1 EMG47002.1 - 0.029 14.3 0.9 0.099 12.6 0.3 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 EMG47002.1 - 0.047 13.3 3.2 0.092 12.3 1.1 2.3 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EMG47002.1 - 0.12 12.3 0.1 0.48 10.4 0.1 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EMG47002.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Zn_clus PF00172.13 EMG47003.1 - 1.8e-05 24.5 12.7 3.5e-05 23.6 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec1 PF00995.18 EMG47004.1 - 2.2e-137 459.0 17.1 2.5e-137 458.8 11.8 1.0 1 0 0 1 1 1 1 Sec1 family TIP49 PF06068.8 EMG47005.1 - 1.1e-165 551.2 0.0 1.4e-165 550.9 0.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EMG47005.1 - 4e-09 36.7 0.0 8.9e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EMG47005.1 - 2e-07 30.3 0.1 4.8e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EMG47005.1 - 0.00011 22.2 0.0 0.029 14.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EMG47005.1 - 0.00051 19.9 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMG47005.1 - 0.00054 20.1 0.1 0.72 10.0 0.0 2.4 1 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EMG47005.1 - 0.0023 17.0 0.1 0.0052 15.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EMG47005.1 - 0.0036 17.6 0.1 0.0088 16.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 EMG47005.1 - 0.0043 17.8 0.0 0.0076 17.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMG47005.1 - 0.0067 16.1 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EMG47005.1 - 0.0068 16.1 0.0 2.9 7.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EMG47005.1 - 0.0091 15.4 0.0 5.2 6.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 EMG47005.1 - 0.015 14.6 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EMG47005.1 - 0.032 14.2 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EMG47005.1 - 0.043 13.2 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EMG47005.1 - 0.046 12.8 0.2 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EMG47005.1 - 0.088 12.4 0.2 3.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase DnaB_C PF03796.10 EMG47005.1 - 0.09 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ATP_bind_1 PF03029.12 EMG47006.1 - 3.2e-84 282.1 0.0 3.6e-84 282.0 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EMG47006.1 - 0.0002 20.8 0.0 0.00041 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain MMR_HSR1 PF01926.18 EMG47006.1 - 0.00076 19.4 0.0 0.0013 18.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase CbiA PF01656.18 EMG47006.1 - 0.00099 18.5 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EMG47006.1 - 0.0011 17.7 0.0 0.002 16.9 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_24 PF13479.1 EMG47006.1 - 0.0026 17.4 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMG47006.1 - 0.0026 18.5 0.2 0.0062 17.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EMG47006.1 - 0.0027 17.4 0.0 0.005 16.5 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 EMG47006.1 - 0.0038 16.6 0.0 0.097 12.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RNA_helicase PF00910.17 EMG47006.1 - 0.0066 16.5 0.0 0.021 14.9 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_29 PF13555.1 EMG47006.1 - 0.0089 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Fer4_NifH PF00142.13 EMG47006.1 - 0.011 14.9 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.1 EMG47006.1 - 0.012 15.5 0.1 0.059 13.3 0.0 2.1 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 EMG47006.1 - 0.016 15.3 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EMG47006.1 - 0.02 14.6 0.0 0.046 13.4 0.0 1.6 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.9 EMG47006.1 - 0.024 13.6 0.0 0.044 12.7 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain DUF87 PF01935.12 EMG47006.1 - 0.027 14.3 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 T2SE PF00437.15 EMG47006.1 - 0.033 13.0 0.0 0.049 12.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF258 PF03193.11 EMG47006.1 - 0.035 13.3 0.0 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Septin PF00735.13 EMG47006.1 - 0.043 12.8 0.1 0.086 11.8 0.0 1.6 2 0 0 2 2 2 0 Septin FtsK_SpoIIIE PF01580.13 EMG47006.1 - 0.044 13.2 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family SRP54 PF00448.17 EMG47006.1 - 0.046 13.1 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA PF00004.24 EMG47006.1 - 0.048 13.8 0.0 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ArsA_ATPase PF02374.10 EMG47006.1 - 0.065 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase TrwB_AAD_bind PF10412.4 EMG47006.1 - 0.069 11.7 0.0 0.095 11.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PPV_E1_C PF00519.12 EMG47006.1 - 0.071 11.7 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase AAA_14 PF13173.1 EMG47006.1 - 0.089 12.7 0.0 0.24 11.2 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EMG47006.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EMG47006.1 - 0.15 12.4 0.0 0.35 11.1 0.0 1.7 2 0 0 2 2 1 0 ABC transporter AAA_33 PF13671.1 EMG47006.1 - 0.16 11.7 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cation_efflux PF01545.16 EMG47007.1 - 3.2e-54 183.9 2.2 5.4e-54 183.1 1.6 1.3 1 0 0 1 1 1 1 Cation efflux family Epiglycanin_C PF14654.1 EMG47007.1 - 1.5 8.8 8.4 3.8 7.5 5.8 1.7 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region DUF2946 PF11162.3 EMG47007.1 - 5.3 7.2 7.0 11 6.2 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Cpn60_TCP1 PF00118.19 EMG47008.1 - 4e-153 510.5 1.7 4.6e-153 510.3 1.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_M24 PF00557.19 EMG47011.1 - 3.9e-09 36.3 0.0 4.6e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Translin PF01997.11 EMG47012.1 - 3e-43 147.7 0.2 3.5e-43 147.5 0.1 1.0 1 0 0 1 1 1 1 Translin family NRDE-2 PF08424.5 EMG47013.1 - 5.6e-08 32.0 1.1 5.6e-08 32.0 0.7 2.9 2 2 0 3 3 3 1 NRDE-2, necessary for RNA interference Suf PF05843.9 EMG47013.1 - 8.5e-05 22.4 8.7 0.0023 17.7 0.1 3.3 2 1 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EMG47013.1 - 0.02 15.5 0.0 21 6.1 0.0 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat PAS_6 PF08348.6 EMG47013.1 - 0.023 14.2 0.0 0.051 13.1 0.0 1.6 1 0 0 1 1 1 0 YheO-like PAS domain ATP-synt_D PF01813.12 EMG47014.1 - 5.3e-63 212.1 7.9 8.3e-63 211.4 5.5 1.3 1 0 0 1 1 1 1 ATP synthase subunit D RICH PF05062.7 EMG47014.1 - 0.32 11.1 5.7 0.16 12.0 1.0 2.6 2 1 0 2 2 2 0 RICH domain Ribosomal_L6e PF01159.14 EMG47014.1 - 1.5 9.1 5.8 0.38 11.0 1.0 2.1 2 1 0 2 2 2 0 Ribosomal protein L6e GAS PF13851.1 EMG47014.1 - 8.4 5.5 14.2 0.23 10.6 0.6 2.6 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding adh_short_C2 PF13561.1 EMG47015.1 - 7.7e-34 117.5 0.1 9e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMG47015.1 - 2.8e-24 85.9 0.0 3.7e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMG47015.1 - 1.5e-10 40.9 0.0 2.2e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 KR domain DFP PF04127.10 EMG47015.1 - 0.00048 19.8 0.1 0.0018 17.9 0.0 1.9 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Epimerase PF01370.16 EMG47015.1 - 0.011 15.2 0.1 0.05 13.0 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EMG47015.1 - 0.072 12.8 0.2 0.19 11.5 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.1 EMG47016.1 - 6.9e-32 111.1 0.0 8.1e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMG47016.1 - 7.1e-25 87.8 0.2 8.8e-25 87.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMG47016.1 - 1.4e-10 41.1 0.1 2.1e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMG47016.1 - 0.016 14.6 0.1 0.023 14.1 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DFP PF04127.10 EMG47016.1 - 0.037 13.6 0.1 0.069 12.7 0.0 1.4 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein RmlD_sub_bind PF04321.12 EMG47016.1 - 0.051 12.4 0.1 0.59 8.9 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain FAD_binding_2 PF00890.19 EMG47017.1 - 1.4e-122 409.5 2.7 2.2e-122 408.9 1.8 1.3 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EMG47017.1 - 3.3e-47 159.5 0.2 5e-47 158.9 0.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.12 EMG47017.1 - 5.7e-06 25.5 0.1 0.0079 15.3 0.0 2.7 3 0 0 3 3 3 2 Thi4 family Pyr_redox_2 PF07992.9 EMG47017.1 - 0.00064 19.6 3.4 0.0018 18.1 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMG47017.1 - 0.001 17.9 0.5 0.055 12.3 0.8 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.19 EMG47017.1 - 0.014 14.3 0.2 0.033 13.1 0.1 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EMG47017.1 - 0.08 11.9 0.2 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain ERp29_N PF07912.8 EMG47019.1 - 0.02 14.8 0.2 0.027 14.3 0.1 1.2 1 0 0 1 1 1 0 ERp29, N-terminal domain DUF4443 PF14544.1 EMG47019.1 - 0.074 12.9 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4443) Candida_ALS_N PF11766.3 EMG47020.1 - 1.9e-84 282.4 10.2 2.7e-84 281.9 7.1 1.2 1 0 0 1 1 1 1 Cell-wall agglutinin N-terminal ligand-sugar binding Candida_ALS PF05792.8 EMG47020.1 - 3.9e-08 33.2 48.2 3.8e-07 30.1 15.6 5.0 4 1 0 4 4 4 2 Candida agglutinin-like (ALS) Xan_ur_permease PF00860.15 EMG47021.1 - 4.7e-70 236.0 31.0 6.5e-70 235.5 21.5 1.1 1 0 0 1 1 1 1 Permease family PEX11 PF05648.9 EMG47023.1 - 7.3e-05 22.1 0.3 0.013 14.7 0.0 2.1 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) SPT16 PF08644.6 EMG47024.1 - 6.6e-52 175.3 0.1 6.6e-52 175.3 0.1 2.3 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EMG47024.1 - 2.4e-42 144.2 4.7 1.3e-41 141.8 1.4 3.1 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EMG47024.1 - 2.9e-21 75.9 0.0 5.2e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EMG47024.1 - 3.6e-19 68.5 0.8 1.8e-18 66.3 0.0 2.7 3 0 0 3 3 3 1 Histone chaperone Rttp106-like DNA_primase_lrg PF04104.9 EMG47025.1 - 5e-79 265.2 0.1 7.5e-79 264.6 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Pkinase PF00069.20 EMG47026.1 - 5.6e-78 261.6 0.0 5.6e-78 261.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG47026.1 - 4.9e-35 120.8 0.0 4.9e-35 120.8 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 EMG47026.1 - 0.00072 18.6 0.2 0.00072 18.6 0.2 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EMG47026.1 - 0.012 14.4 0.1 0.02 13.7 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4557 PF15101.1 EMG47026.1 - 0.57 9.9 14.6 1 9.1 10.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Spore_III_AF PF09581.5 EMG47026.1 - 0.98 9.2 8.2 5.8 6.7 4.7 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) APH PF01636.18 EMG47026.1 - 2.1 8.0 13.3 12 5.5 9.2 2.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF4407 PF14362.1 EMG47026.1 - 2.2 7.1 13.6 3.1 6.6 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PAT1 PF09770.4 EMG47026.1 - 5.4 5.1 20.4 7 4.7 14.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 EMG47026.1 - 5.5 5.0 31.0 7 4.7 21.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2406 PF10295.4 EMG47027.1 - 7.3e-28 96.8 0.2 1.8e-27 95.6 0.1 1.7 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) YL1_C PF08265.6 EMG47028.1 - 3e-14 52.2 0.3 6.4e-14 51.2 0.2 1.6 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain UAA PF08449.6 EMG47029.1 - 2.2e-11 43.2 14.1 2.8e-11 42.9 9.7 1.1 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EMG47029.1 - 3.9e-11 42.5 1.4 8.9e-11 41.3 0.9 1.6 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 EMG47029.1 - 2.8e-07 30.3 19.3 6.9e-06 25.7 6.9 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 EMG47029.1 - 4.9e-05 23.4 0.9 4.9e-05 23.4 0.6 3.6 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EMG47029.1 - 0.001 19.1 4.3 0.001 19.1 3.0 3.2 2 1 1 3 3 3 2 EamA-like transporter family DUF202 PF02656.10 EMG47029.1 - 0.12 12.5 0.5 0.12 12.5 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Gram_pos_anchor PF00746.16 EMG47029.1 - 0.18 11.6 0.0 0.18 11.6 0.0 3.5 5 0 0 5 5 5 0 Gram positive anchor MerC PF03203.9 EMG47029.1 - 1.9 8.8 7.6 0.51 10.7 1.0 2.7 2 1 0 2 2 2 0 MerC mercury resistance protein IspA PF04279.10 EMG47029.1 - 3.8 7.4 12.4 9.1 6.2 0.7 3.3 2 1 1 3 3 3 0 Intracellular septation protein A EcsB PF05975.7 EMG47029.1 - 3.8 5.8 17.1 0.12 10.8 4.2 2.1 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB DUF4131 PF13567.1 EMG47029.1 - 8.5 5.7 8.0 0.29 10.5 0.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) AFG1_ATPase PF03969.11 EMG47030.1 - 1.1e-76 258.0 0.1 1.1e-74 251.4 0.0 2.0 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EMG47030.1 - 0.0009 19.2 0.1 0.13 12.1 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EMG47030.1 - 0.0061 16.2 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EMG47030.1 - 0.0064 16.6 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 EMG47030.1 - 0.0092 15.6 0.7 0.016 14.8 0.1 1.7 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_22 PF13401.1 EMG47030.1 - 0.035 14.2 0.1 0.14 12.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EMG47030.1 - 0.037 13.7 0.3 0.39 10.3 0.0 2.4 2 1 1 3 3 3 0 Archaeal ATPase NACHT PF05729.7 EMG47030.1 - 0.042 13.4 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.16 EMG47030.1 - 0.049 12.7 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EMG47030.1 - 0.075 13.3 0.0 0.24 11.7 0.0 1.7 1 1 1 2 2 2 0 ABC transporter RNA_helicase PF00910.17 EMG47030.1 - 0.097 12.8 0.1 0.34 11.1 0.0 2.1 3 0 0 3 3 2 0 RNA helicase Rdx PF10262.4 EMG47031.1 - 6.7e-25 86.9 0.2 9e-25 86.5 0.1 1.2 1 0 0 1 1 1 1 Rdx family DUF605 PF04652.11 EMG47032.1 - 3.2 7.0 25.0 4 6.7 17.3 1.2 1 0 0 1 1 1 0 Vta1 like TPP_enzyme_M PF00205.17 EMG47034.1 - 1.6e-36 125.0 0.0 6.4e-36 123.1 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 EMG47034.1 - 5.8e-32 110.5 0.0 8.8e-32 109.9 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EMG47034.1 - 3.6e-12 46.1 0.0 7.7e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain OCC1 PF15506.1 EMG47034.1 - 0.53 10.2 3.6 17 5.4 0.0 2.8 3 0 0 3 3 3 0 OCC1 family HLH PF00010.21 EMG47035.1 - 2.3e-12 46.3 3.8 6.2e-12 45.0 2.6 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Nucleoplasmin PF03066.10 EMG47035.1 - 0.28 10.7 16.1 0.67 9.4 11.2 1.7 1 0 0 1 1 1 0 Nucleoplasmin DUF4199 PF13858.1 EMG47035.1 - 6.4 6.6 5.6 1.5 8.7 1.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DnaJ PF00226.26 EMG47036.1 - 1e-18 66.8 0.6 3.3e-18 65.1 0.4 1.9 1 0 0 1 1 1 1 DnaJ domain SLT_L PF14718.1 EMG47036.1 - 0.063 13.0 0.2 0.15 11.8 0.1 1.6 1 1 0 1 1 1 0 Soluble lytic murein transglycosylase L domain DltD_M PF04918.7 EMG47036.1 - 0.17 12.0 9.8 0.44 10.7 6.8 1.7 1 0 0 1 1 1 0 DltD central region Fis1_TPR_C PF14853.1 EMG47036.1 - 0.59 10.0 9.5 1.1 9.2 1.1 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DNA_topoisoIV PF00521.15 EMG47037.1 - 8.3e-125 416.9 0.1 8.3e-125 416.9 0.1 1.7 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EMG47037.1 - 4e-34 117.3 3.5 9e-34 116.1 2.4 1.6 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EMG47037.1 - 6.2e-12 45.3 0.1 3.6e-11 42.9 0.0 2.4 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EMG47037.1 - 5.4e-10 38.9 0.0 1.3e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LicD PF04991.8 EMG47039.1 - 2.1e-46 158.6 0.5 2.1e-46 158.6 0.4 4.7 3 1 0 3 3 3 1 LicD family MIP-T3 PF10243.4 EMG47039.1 - 0.51 8.7 64.5 0.77 8.1 44.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 EMG47039.1 - 1.3 7.3 49.0 1.9 6.8 33.9 1.1 1 0 0 1 1 1 0 Daxx Family GATA PF00320.22 EMG47041.1 - 2.3e-17 62.0 3.4 4.6e-17 61.0 2.4 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EMG47041.1 - 5.1e-13 48.3 3.6 1e-12 47.3 2.5 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DZR PF12773.2 EMG47041.1 - 0.085 12.6 0.8 0.33 10.8 0.6 1.7 1 1 1 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 EMG47041.1 - 0.14 11.5 0.2 0.34 10.2 0.2 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding LRR_9 PF14580.1 EMG47044.1 - 4.8e-16 58.8 0.3 4.8e-16 58.8 0.2 1.5 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.1 EMG47044.1 - 2.1e-10 40.1 15.6 3.3e-09 36.3 5.4 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EMG47044.1 - 2.8e-08 33.1 12.3 2.3e-07 30.2 1.7 4.4 3 2 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMG47044.1 - 6.7e-06 25.4 8.9 0.049 13.6 0.9 4.8 3 2 0 3 3 3 3 Leucine Rich Repeat LRR_6 PF13516.1 EMG47044.1 - 0.0007 19.4 12.4 1.2 9.3 0.5 4.7 4 0 0 4 4 4 2 Leucine Rich repeat LRR_7 PF13504.1 EMG47044.1 - 0.027 14.5 12.9 1.1 9.7 0.1 5.0 4 1 0 4 4 4 0 Leucine rich repeat LRR_5 PF13306.1 EMG47044.1 - 0.26 10.9 7.1 0.18 11.4 2.8 2.0 1 1 0 1 1 1 0 Leucine rich repeats (6 copies) mRNA_cap_enzyme PF01331.14 EMG47045.1 - 1.2e-64 217.5 0.0 1.7e-64 217.1 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EMG47045.1 - 3.3e-24 85.2 0.4 6.3e-24 84.3 0.3 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EMG47045.1 - 5.6e-07 29.1 0.0 3e-05 23.4 0.0 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain NAD_binding_6 PF08030.7 EMG47046.1 - 1.4e-26 93.3 0.0 3e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMG47046.1 - 1.4e-25 89.2 0.0 2.9e-25 88.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EMG47046.1 - 1.1e-19 70.7 12.4 2.6e-19 69.5 8.6 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EMG47046.1 - 0.052 14.1 0.0 2.7 8.5 0.0 2.5 1 1 0 2 2 2 0 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.7 EMG47047.1 - 7e-24 83.7 0.1 1.3e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EMG47047.1 - 5.3e-20 71.9 0.0 7.8e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMG47047.1 - 2.2e-19 69.7 11.7 2.2e-19 69.7 8.1 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component DUF3592 PF12158.3 EMG47047.1 - 5.4 6.7 7.7 74 3.1 5.3 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) DnaJ-X PF14308.1 EMG47048.1 - 6.9e-67 224.6 11.0 6.9e-67 224.6 7.6 2.1 2 1 1 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 EMG47048.1 - 2.7e-26 91.0 1.8 8.4e-26 89.4 0.8 2.3 2 0 0 2 2 2 1 DnaJ domain DUF964 PF06133.6 EMG47048.1 - 0.005 16.8 0.2 0.005 16.8 0.2 4.2 4 1 0 4 4 4 1 Protein of unknown function (DUF964) Phage_int_SAM_4 PF13495.1 EMG47048.1 - 0.047 14.0 2.9 1.9 8.8 0.1 2.9 2 1 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain CUT PF02376.10 EMG47049.1 - 0.023 14.4 0.2 0.058 13.2 0.1 1.7 1 0 0 1 1 1 0 CUT domain Prothymosin PF03247.9 EMG47049.1 - 1.1 9.4 11.0 0.34 11.0 5.6 1.6 2 0 0 2 2 2 0 Prothymosin/parathymosin family SOBP PF15279.1 EMG47049.1 - 2.2 8.5 14.3 2.9 8.1 9.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein PHD PF00628.24 EMG47050.1 - 7.4e-14 51.1 55.7 1.2e-07 31.3 7.8 6.2 6 0 0 6 6 6 3 PHD-finger BAH PF01426.13 EMG47050.1 - 4.5e-13 48.9 0.1 1.7e-12 47.1 0.0 2.0 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H_2 PF13832.1 EMG47050.1 - 4.9e-10 39.3 1.3 4.9e-10 39.3 0.9 4.6 4 0 0 4 4 4 2 PHD-zinc-finger like domain PHD_2 PF13831.1 EMG47050.1 - 3.5e-08 32.6 1.3 3.5e-08 32.6 0.9 4.6 5 0 0 5 5 5 2 PHD-finger zf-HC5HC2H PF13771.1 EMG47050.1 - 2e-07 31.0 1.6 2e-07 31.0 1.1 5.1 5 1 0 5 5 5 1 PHD-like zinc-binding domain Acetyltransf_1 PF00583.19 EMG47052.1 - 5.4e-06 26.3 0.1 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMG47052.1 - 1.4e-05 25.1 0.0 2.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMG47052.1 - 3e-05 23.8 0.0 5.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMG47052.1 - 0.0026 17.4 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein PT PF04886.7 EMG47053.1 - 5.4e-14 51.2 101.5 0.24 10.7 3.2 6.5 3 2 1 4 4 4 1 PT repeat Zn_clus PF00172.13 EMG47054.1 - 1.3e-08 34.5 8.4 2.9e-08 33.4 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DGF-1_C PF11040.3 EMG47054.1 - 8 6.4 8.5 3 7.7 3.5 2.1 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Prefoldin_2 PF01920.15 EMG47055.1 - 4.6e-19 68.1 3.7 5.5e-19 67.8 2.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF677 PF05055.7 EMG47055.1 - 0.031 12.9 2.2 0.035 12.7 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) BLOC1_2 PF10046.4 EMG47055.1 - 0.045 13.8 5.1 4.2 7.5 1.2 2.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_23 PF13476.1 EMG47055.1 - 0.11 12.8 7.4 0.12 12.6 5.1 1.1 1 0 0 1 1 1 0 AAA domain HAUS2 PF15003.1 EMG47055.1 - 0.13 11.3 0.5 0.15 11.0 0.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 YvrJ PF12841.2 EMG47055.1 - 0.23 10.7 0.1 0.23 10.7 0.1 2.0 3 0 0 3 3 3 0 YvrJ protein family Nsp1_C PF05064.8 EMG47055.1 - 0.23 11.0 3.7 0.55 9.8 0.2 2.1 1 1 1 2 2 2 0 Nsp1-like C-terminal region HLH PF00010.21 EMG47056.1 - 1.1e-12 47.3 0.2 3e-12 46.0 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sec23_trunk PF04811.10 EMG47057.1 - 1.3e-70 237.4 0.0 2e-70 236.9 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 EMG47057.1 - 4.2e-33 113.7 1.0 8.2e-33 112.7 0.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 EMG47057.1 - 6.7e-32 109.0 1.4 8e-32 108.7 0.1 1.8 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Gelsolin PF00626.17 EMG47057.1 - 3.1e-13 49.2 0.0 6.9e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.10 EMG47057.1 - 3.2e-12 45.8 8.4 7e-12 44.7 5.8 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger zf-RanBP PF00641.13 EMG47057.1 - 0.093 11.8 0.1 0.23 10.5 0.1 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Oxidored_FMN PF00724.15 EMG47058.1 - 5.1e-17 61.8 0.0 5.4e-17 61.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NIT PF08376.5 EMG47058.1 - 0.084 12.3 0.0 0.084 12.3 0.0 1.0 1 0 0 1 1 1 0 Nitrate and nitrite sensing Sec3-PIP2_bind PF15277.1 EMG47060.1 - 5.4e-18 64.6 0.8 1.1e-17 63.6 0.2 1.9 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH 3Beta_HSD PF01073.14 EMG47062.1 - 3.2e-81 272.0 0.0 3.9e-81 271.8 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMG47062.1 - 3.5e-34 118.2 0.0 4.4e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMG47062.1 - 2.2e-21 75.9 0.0 8.6e-21 73.9 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EMG47062.1 - 5.4e-13 48.4 0.0 8.5e-13 47.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EMG47062.1 - 3.2e-12 46.8 0.0 4.4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EMG47062.1 - 4.8e-08 32.2 0.0 9.1e-08 31.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EMG47062.1 - 1.3e-06 28.4 0.0 3.4e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EMG47062.1 - 6.9e-06 25.4 0.0 1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 EMG47062.1 - 0.00042 20.0 0.0 0.0024 17.5 0.0 2.0 1 1 0 1 1 1 1 KR domain TAXi_C PF14541.1 EMG47062.1 - 0.093 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Semialdhyde_dh PF01118.19 EMG47062.1 - 0.13 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Piwi PF02171.12 EMG47063.1 - 1.3e-74 250.8 1.6 1.9e-74 250.3 1.1 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EMG47063.1 - 4.5e-14 51.9 1.1 3.1e-13 49.2 0.0 2.4 2 0 0 2 2 2 1 PAZ domain DUF1785 PF08699.5 EMG47063.1 - 5.2e-05 22.5 0.1 0.00011 21.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) adh_short PF00106.20 EMG47064.1 - 5.5e-27 94.7 0.0 8.7e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMG47064.1 - 2.5e-15 56.8 0.0 8.4e-15 55.1 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMG47064.1 - 9.5e-12 44.9 0.0 1.6e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Peptidase_M41 PF01434.13 EMG47065.1 - 2.4e-70 236.3 0.2 4.5e-70 235.4 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EMG47065.1 - 4.8e-42 143.2 0.0 3.3e-41 140.5 0.0 2.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMG47065.1 - 1.8e-05 24.8 0.1 9.2e-05 22.4 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 EMG47065.1 - 3.7e-05 22.6 0.6 0.00011 21.0 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 EMG47065.1 - 5.5e-05 23.9 0.1 0.00019 22.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EMG47065.1 - 0.00024 21.2 1.8 0.035 14.2 0.2 3.2 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EMG47065.1 - 0.00033 19.7 0.0 0.0065 15.5 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EMG47065.1 - 0.00081 19.1 0.0 0.0034 17.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EMG47065.1 - 0.001 18.9 0.2 0.036 13.9 0.0 3.1 4 0 0 4 4 3 1 AAA domain AAA_25 PF13481.1 EMG47065.1 - 0.0013 18.1 2.3 0.12 11.7 0.5 3.1 2 1 2 4 4 4 1 AAA domain AAA_19 PF13245.1 EMG47065.1 - 0.0022 17.7 2.2 0.0063 16.2 1.5 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EMG47065.1 - 0.0045 16.4 0.3 0.011 15.1 0.1 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 EMG47065.1 - 0.021 15.1 0.0 0.072 13.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EMG47065.1 - 0.022 13.8 0.0 0.046 12.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin KaiC PF06745.8 EMG47065.1 - 0.029 13.5 0.1 0.46 9.5 0.1 2.5 2 0 0 2 2 2 0 KaiC AAA_33 PF13671.1 EMG47065.1 - 0.034 14.0 0.0 0.089 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 EMG47065.1 - 0.041 13.8 1.1 0.14 12.0 0.0 2.5 3 1 0 3 3 2 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EMG47065.1 - 0.043 12.9 0.2 0.091 11.9 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EMG47065.1 - 0.065 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain SOG2 PF10428.4 EMG47067.1 - 0.23 10.0 4.9 0.28 9.8 3.4 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein TBPIP PF07106.8 EMG47068.1 - 1.9e-22 79.5 19.1 2.7e-22 79.1 13.3 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TNF PF00229.13 EMG47068.1 - 0.04 13.4 0.5 0.063 12.8 0.4 1.4 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family DUF3573 PF12097.3 EMG47068.1 - 0.045 12.3 8.4 0.055 12.0 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Cyclin PF08613.6 EMG47068.1 - 0.053 13.9 0.2 0.077 13.4 0.2 1.3 1 0 0 1 1 1 0 Cyclin Het-C PF07217.6 EMG47068.1 - 0.067 11.3 6.4 0.27 9.4 4.4 1.7 1 1 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF1664 PF07889.7 EMG47068.1 - 0.4 10.4 11.2 0.45 10.3 2.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin PF00804.20 EMG47068.1 - 1.8 8.7 15.9 0.33 11.1 7.7 2.2 2 1 1 3 3 3 0 Syntaxin SRCR_2 PF15494.1 EMG47068.1 - 3.8 7.8 6.7 0.72 10.1 0.2 2.7 2 1 2 4 4 4 0 Scavenger receptor cysteine-rich domain Syntaxin-6_N PF09177.6 EMG47068.1 - 4.9 7.6 8.8 69 3.9 6.0 2.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal CAP_GLY PF01302.20 EMG47069.1 - 8.1e-17 60.6 0.3 3.7e-16 58.5 0.1 2.0 2 0 0 2 2 2 1 CAP-Gly domain LRR_4 PF12799.2 EMG47069.1 - 3.1e-15 55.3 40.6 0.0022 17.5 6.5 6.7 3 2 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG47069.1 - 2.5e-13 49.5 30.1 3.2e-05 23.5 4.9 5.1 3 2 2 5 5 5 4 Leucine rich repeat LRR_7 PF13504.1 EMG47069.1 - 4.6e-09 35.0 19.7 0.2 11.9 0.0 8.7 9 0 0 9 9 9 4 Leucine rich repeat LRR_6 PF13516.1 EMG47069.1 - 5.7e-08 32.0 30.0 0.39 10.9 0.0 9.4 8 1 0 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.28 EMG47069.1 - 1.6e-07 30.3 31.3 0.016 15.1 0.1 9.2 7 1 2 9 9 9 4 Leucine Rich Repeat FNIP PF05725.7 EMG47069.1 - 0.011 15.6 1.5 0.4 10.6 0.0 4.0 3 1 0 3 3 3 0 FNIP Repeat Helicase_C PF00271.26 EMG47070.1 - 4e-20 71.4 0.1 1.2e-19 69.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMG47070.1 - 7.8e-19 67.7 0.0 5.1e-18 65.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EMG47070.1 - 1.3e-17 64.1 0.0 1.3e-17 64.1 0.0 3.7 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EMG47070.1 - 0.0034 17.5 0.0 0.022 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain GN3L_Grn1 PF08701.6 EMG47071.1 - 1.3e-25 89.1 15.8 3.8e-25 87.5 10.9 1.9 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EMG47071.1 - 4.2e-21 75.0 1.2 2.2e-15 56.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EMG47071.1 - 2.8e-10 39.6 0.1 6.5e-08 32.0 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 EMG47071.1 - 3.4e-06 26.6 0.1 0.022 14.1 0.0 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EMG47071.1 - 4.1e-05 22.8 0.2 7e-05 22.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EMG47071.1 - 7e-05 22.7 7.9 0.25 11.1 1.9 4.0 2 2 1 3 3 3 2 Dynamin family Miro PF08477.8 EMG47071.1 - 0.0004 20.8 1.0 0.11 12.9 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AIG1 PF04548.11 EMG47071.1 - 0.0053 15.8 0.1 0.037 13.1 0.0 2.1 2 0 0 2 2 2 1 AIG1 family ArgK PF03308.11 EMG47071.1 - 0.011 14.5 0.0 0.027 13.2 0.0 1.7 1 0 0 1 1 1 0 ArgK protein Gtr1_RagA PF04670.7 EMG47071.1 - 0.066 12.3 0.1 0.21 10.6 0.0 1.8 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Nop14 PF04147.7 EMG47071.1 - 0.081 10.8 27.7 0.16 9.8 19.2 1.4 1 0 0 1 1 1 0 Nop14-like family AAA_16 PF13191.1 EMG47071.1 - 0.13 12.2 1.0 0.94 9.4 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 EMG47071.1 - 0.26 12.1 0.0 0.26 12.1 0.0 2.8 2 1 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EMG47071.1 - 0.27 11.5 0.0 0.27 11.5 0.0 2.8 2 1 0 2 2 2 0 AAA domain V_ATPase_I PF01496.14 EMG47072.1 - 5.6 4.6 7.9 6.4 4.4 5.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GDA1_CD39 PF01150.12 EMG47073.1 - 1e-122 409.7 2.0 1.4e-122 409.3 1.4 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF1162 PF06650.7 EMG47074.1 - 2.2e-85 286.2 0.9 2.3e-82 276.3 0.2 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EMG47074.1 - 4.1e-44 148.8 1.0 1.5e-43 147.0 0.7 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EMG47074.1 - 0.0014 18.6 0.0 0.0037 17.3 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain Formyl_trans_N PF00551.14 EMG47075.1 - 4.4e-33 114.3 0.0 6.2e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 EMG47075.1 - 0.00071 19.6 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Rrn6 PF10214.4 EMG47076.1 - 2.2e-103 346.8 32.3 2.2e-103 346.8 22.4 2.7 2 1 0 2 2 2 1 RNA polymerase I-specific transcription-initiation factor HPIH PF13323.1 EMG47076.1 - 1.4 8.5 7.6 0.55 9.9 2.7 2.2 2 0 0 2 2 2 0 N-terminal domain with HPIH motif Glyco_hydro_63 PF03200.11 EMG47077.1 - 1.4e-256 853.3 4.6 1.5e-255 849.9 3.2 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EMG47077.1 - 7.4e-06 24.8 1.5 1.2e-05 24.1 1.1 1.2 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 EMG47077.1 - 0.00032 19.5 0.0 0.00092 18.0 0.0 1.6 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Bac_rhamnosid PF05592.6 EMG47077.1 - 0.02 13.0 0.0 0.04 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase Trp_syntA PF00290.15 EMG47078.1 - 6.4e-93 310.0 0.1 1e-92 309.3 0.1 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EMG47078.1 - 6e-46 157.0 0.3 1.2e-45 156.1 0.2 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Lipase_GDSL_2 PF13472.1 EMG47078.1 - 0.1 12.7 0.0 0.42 10.7 0.0 1.9 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family SecIII_SopE_N PF05364.9 EMG47078.1 - 0.12 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Salmonella type III secretion SopE effector N-terminus ELFV_dehydrog PF00208.16 EMG47079.1 - 1.1e-85 287.1 5.8 1.3e-85 286.8 4.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EMG47079.1 - 1.6e-46 157.1 0.0 3.2e-46 156.1 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Mcp5_PH PF12814.2 EMG47080.1 - 3.1e-40 136.9 2.1 8.7e-40 135.4 0.1 3.0 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology Nodulin-like PF06813.8 EMG47081.1 - 9.2e-18 64.3 16.4 7.8e-16 58.0 7.0 2.8 2 1 0 2 2 2 2 Nodulin-like MFS_1 PF07690.11 EMG47081.1 - 1.7e-12 46.7 33.5 1.7e-12 46.7 23.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily EF-hand_1 PF00036.27 EMG47082.1 - 1.7e-37 123.8 8.8 8.4e-09 34.1 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EMG47082.1 - 1.2e-32 111.8 2.8 2.5e-16 59.5 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EMG47082.1 - 1.5e-28 98.1 7.6 7e-13 47.9 0.1 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EMG47082.1 - 3.4e-28 95.6 9.0 1.7e-08 33.4 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EMG47082.1 - 4.7e-27 91.4 6.7 1.2e-08 34.0 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_9 PF14658.1 EMG47082.1 - 5.4e-14 51.8 0.1 1.3e-07 31.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 EMG47082.1 - 3.2e-10 40.0 0.0 0.00032 20.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EMG47082.1 - 5.5e-10 38.9 2.0 5.9e-05 22.7 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 EMG47082.1 - 2.6e-08 33.3 0.1 0.034 13.7 0.0 3.8 4 0 0 4 4 4 2 Uncharacterised protein family (UPF0154) TerB PF05099.8 EMG47082.1 - 9.6e-07 28.6 0.3 0.0033 17.1 0.0 2.2 2 0 0 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 EMG47082.1 - 0.00081 18.9 0.0 0.18 11.3 0.0 2.4 1 1 0 2 2 2 1 Caleosin related protein EF-hand_10 PF14788.1 EMG47082.1 - 0.0037 16.8 1.6 0.015 14.9 0.0 2.6 2 1 1 3 3 3 1 EF hand DUF533 PF04391.7 EMG47082.1 - 0.018 14.3 1.9 2.9 7.2 0.1 3.2 2 2 2 4 4 4 0 Protein of unknown function (DUF533) Toprim_2 PF13155.1 EMG47082.1 - 0.023 15.0 0.5 1 9.7 0.0 2.1 1 1 1 2 2 2 0 Toprim-like Poly_export PF02563.11 EMG47082.1 - 0.028 14.1 0.0 0.27 11.0 0.0 2.2 1 1 1 2 2 2 0 Polysaccharide biosynthesis/export protein RNA_pol_Rpb4 PF03874.11 EMG47082.1 - 0.064 13.2 0.3 10 6.1 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb4 VCBS PF13517.1 EMG47082.1 - 0.37 11.1 4.9 2.5 8.5 2.2 2.6 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Dockerin_1 PF00404.13 EMG47082.1 - 0.64 9.8 17.5 4.3 7.2 0.1 4.2 4 0 0 4 4 4 0 Dockerin type I repeat PCI_Csn8 PF10075.4 EMG47083.1 - 0.0027 17.4 0.9 0.0052 16.5 0.7 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SR-25 PF10500.4 EMG47083.1 - 0.018 14.5 6.1 0.024 14.1 4.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Glyco_trans_1_4 PF13692.1 EMG47084.1 - 1.8e-16 60.5 0.0 2.6e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EMG47084.1 - 2.1e-13 50.0 0.0 3.3e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EMG47084.1 - 0.055 13.5 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EMG47084.1 - 0.07 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Hist_deacetyl PF00850.14 EMG47085.1 - 3.2e-66 223.7 0.0 4.1e-66 223.3 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain IMS PF00817.15 EMG47086.1 - 2.1e-36 124.9 0.0 5.8e-36 123.5 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EMG47086.1 - 3.8e-15 55.9 0.0 1.1e-14 54.3 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT PF00533.21 EMG47086.1 - 7.9e-07 29.1 2.0 1.4e-06 28.3 0.2 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EMG47086.1 - 6e-05 22.8 0.2 0.00011 21.9 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.3 EMG47086.1 - 0.00031 20.6 0.0 0.0088 16.0 0.0 3.2 3 0 0 3 3 3 1 IMS family HHH motif DUF1805 PF08827.6 EMG47086.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) DSPc PF00782.15 EMG47088.1 - 1.1e-10 41.2 1.2 5.7e-09 35.6 0.0 3.0 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain NIF3 PF01784.13 EMG47089.1 - 8.5e-72 241.6 0.1 1.1e-71 241.2 0.1 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Kelch_4 PF13418.1 EMG47090.1 - 2.7e-16 59.0 3.5 5.2e-08 32.5 0.0 4.6 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EMG47090.1 - 1.4e-15 56.8 4.5 1.2e-05 25.1 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.20 EMG47090.1 - 1.2e-12 47.1 6.2 1.4e-05 24.5 0.1 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 EMG47090.1 - 1.7e-12 46.9 6.0 0.00016 21.7 0.1 5.6 6 0 0 6 6 6 2 Kelch motif Kelch_3 PF13415.1 EMG47090.1 - 1.4e-11 44.2 0.2 0.00033 20.7 0.0 4.7 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 EMG47090.1 - 4.2e-09 35.8 3.3 0.026 14.3 0.1 4.6 4 0 0 4 4 4 2 Kelch motif BTB PF00651.26 EMG47090.1 - 0.044 13.7 0.0 0.45 10.5 0.0 2.3 2 0 0 2 2 2 0 BTB/POZ domain Mito_fiss_reg PF05308.6 EMG47090.1 - 0.069 12.5 1.8 0.14 11.4 1.2 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator TMEM171 PF15471.1 EMG47090.1 - 0.29 9.8 1.8 0.48 9.1 1.2 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Phosphodiest PF01663.17 EMG47091.1 - 4.3e-84 282.9 0.9 5.8e-84 282.5 0.6 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase RNase_PH PF01138.16 EMG47092.1 - 1.4e-15 57.8 0.0 2.1e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EMG47092.1 - 3.5e-06 26.8 0.1 1.6e-05 24.7 0.0 2.1 2 1 0 2 2 2 1 3' exoribonuclease family, domain 2 Gly_transf_sug PF04488.10 EMG47093.1 - 1.5e-20 73.5 0.1 4.2e-20 72.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TMEM240 PF15207.1 EMG47093.1 - 0.15 11.6 0.3 0.25 10.9 0.2 1.3 1 0 0 1 1 1 0 TMEM240 family Hyphal_reg_CWP PF11765.3 EMG47094.1 - 2.3e-120 401.3 1.6 3.4e-120 400.7 1.1 1.2 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal FAD_binding_1 PF00667.15 EMG47095.1 - 9.7e-67 224.6 0.0 2.4e-66 223.3 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EMG47095.1 - 1.2e-09 38.6 0.0 4.2e-09 36.9 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EMG47095.1 - 0.11 12.5 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Hyphal_reg_CWP PF11765.3 EMG47096.1 - 3.2e-146 486.3 8.1 3.2e-146 486.3 5.6 1.7 2 0 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal Reg_prop PF07494.6 EMG47096.1 - 0.053 13.5 1.9 1.6 9.0 0.2 3.3 2 0 0 2 2 2 0 Two component regulator propeller RNase_H2-Ydr279 PF09468.5 EMG47097.1 - 1.3e-37 129.6 10.0 1.6e-37 129.3 6.9 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Band_7 PF01145.20 EMG47098.1 - 4.6e-21 75.5 0.0 6e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family CO_deh_flav_C PF03450.12 EMG47098.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase flavoprotein C-terminal domain Acyltransferase PF01553.16 EMG47101.1 - 1e-09 37.8 0.0 5.8e-09 35.4 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase Rrp15p PF07890.7 EMG47102.1 - 2.8e-36 124.4 13.2 2.8e-36 124.4 9.1 2.2 2 1 0 2 2 2 1 Rrp15p Daxx PF03344.10 EMG47102.1 - 0.12 10.8 23.8 0.14 10.6 16.5 1.0 1 0 0 1 1 1 0 Daxx Family Trypan_PARP PF05887.6 EMG47102.1 - 2.5 7.8 6.7 4.2 7.1 4.7 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Dsh_C PF12316.3 EMG47102.1 - 5.7 7.0 6.2 4.6 7.2 3.1 1.6 1 1 1 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Kinesin PF00225.18 EMG47103.1 - 1.2e-101 339.7 6.9 1.2e-101 339.7 4.8 2.2 1 1 1 2 2 2 1 Kinesin motor domain PPR_2 PF13041.1 EMG47104.1 - 0.00012 22.0 0.6 5.7 7.0 0.0 4.7 5 0 0 5 5 5 3 PPR repeat family TPR_12 PF13424.1 EMG47104.1 - 0.0095 15.8 0.4 2.9 7.8 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.15 EMG47104.1 - 0.043 13.7 6.4 7.3 6.8 0.0 5.1 6 0 0 6 6 6 0 PPR repeat Pescadillo_N PF06732.6 EMG47105.1 - 1.4e-115 385.4 4.1 1.4e-115 385.4 2.8 2.4 3 0 0 3 3 3 1 Pescadillo N-terminus BRCT PF00533.21 EMG47105.1 - 1.1e-10 41.4 0.1 6.1e-10 39.1 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain ATP-synt_S1 PF05827.7 EMG47106.1 - 7.7e-14 51.6 0.4 2.7e-13 49.8 0.2 1.8 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) ERG4_ERG24 PF01222.12 EMG47107.1 - 1.9e-110 369.3 2.8 4.8e-94 315.3 1.2 2.0 1 1 1 2 2 2 2 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EMG47107.1 - 0.00011 21.6 0.3 0.00014 21.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DDE_Tnp_Tn3 PF01526.12 EMG47107.1 - 0.16 10.5 0.0 0.24 9.9 0.0 1.3 1 0 0 1 1 1 0 Tn3 transposase DDE domain AMPKBI PF04739.10 EMG47108.1 - 6.4e-34 115.8 3.0 6.4e-34 115.8 2.1 2.4 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain Suf PF05843.9 EMG47108.1 - 1.9 8.1 8.2 4.4 6.9 5.7 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med18 PF09637.5 EMG47110.1 - 9e-101 336.5 4.1 1e-100 336.3 2.8 1.0 1 0 0 1 1 1 1 Med18 protein Ribosomal_L3 PF00297.17 EMG47112.1 - 3.8e-120 400.1 9.6 4.6e-120 399.9 6.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 WD40 PF00400.27 EMG47113.1 - 3.1e-22 77.5 7.4 7e-08 32.0 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 EMG47113.1 - 6e-06 26.0 0.2 0.95 9.2 0.0 4.9 4 1 0 4 4 4 3 Ciliary BBSome complex subunit 2, middle region Y_phosphatase2 PF03162.8 EMG47114.1 - 6.4e-43 145.9 0.3 1e-41 142.0 0.2 2.0 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EMG47114.1 - 1.1e-05 25.7 0.0 2.1e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EMG47114.1 - 0.0032 16.8 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EMG47114.1 - 0.025 14.1 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Lactamase_B PF00753.22 EMG47115.1 - 1.7e-24 86.5 3.0 3.1e-24 85.7 2.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily SGS PF05002.10 EMG47115.1 - 1.3e-22 79.3 3.5 4.4e-22 77.6 2.4 1.9 1 0 0 1 1 1 1 SGS domain CS PF04969.11 EMG47115.1 - 2.6e-20 72.7 1.3 2.6e-20 72.7 0.9 2.6 4 0 0 4 4 1 1 CS domain MFS_1 PF07690.11 EMG47115.1 - 2.1e-17 62.8 52.5 2.4e-16 59.3 15.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_11 PF13414.1 EMG47115.1 - 5.9e-12 45.0 3.7 6.7e-07 28.8 0.2 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EMG47115.1 - 1.6e-07 30.7 3.6 0.0031 17.3 0.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMG47115.1 - 2.7e-06 27.2 0.2 5.4e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMG47115.1 - 2e-05 23.9 7.7 0.014 14.9 1.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMG47115.1 - 0.00099 19.7 0.1 0.031 14.9 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMG47115.1 - 0.0024 17.5 9.1 0.0071 16.0 1.4 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Lactamase_B_2 PF12706.2 EMG47115.1 - 0.014 14.9 1.9 0.054 13.0 1.3 2.0 1 1 0 1 1 1 0 Beta-lactamase superfamily domain TPR_19 PF14559.1 EMG47115.1 - 0.02 15.2 0.8 0.054 13.8 0.5 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMG47115.1 - 0.027 14.9 2.9 5.8 7.6 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMG47115.1 - 0.23 11.7 2.2 2.1 8.7 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat FMN_red PF03358.10 EMG47116.1 - 9.7e-07 28.4 0.0 1.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 EMG47116.1 - 8.1e-05 22.6 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 EMG47116.1 - 9e-05 22.0 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold zf-CHCC PF10276.4 EMG47117.1 - 8.6e-15 54.2 0.2 1.3e-14 53.6 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger domain zf-C2H2_3 PF13878.1 EMG47117.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO LrgB PF04172.11 EMG47118.1 - 2.1e-23 82.5 3.8 2.1e-23 82.5 2.6 2.6 3 0 0 3 3 3 2 LrgB-like family NBP1 PF08537.5 EMG47118.1 - 2.2 7.4 7.5 2.9 6.9 5.2 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 LRR_4 PF12799.2 EMG47119.1 - 3.8e-15 55.0 36.6 2.9e-05 23.5 3.3 7.4 7 0 0 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG47119.1 - 2.5e-14 52.7 33.0 4.7e-07 29.4 0.1 6.5 6 1 1 7 7 7 4 Leucine rich repeat LRR_1 PF00560.28 EMG47119.1 - 4.5e-08 32.0 36.0 2.3 8.5 2.3 10.6 9 1 1 10 10 10 6 Leucine Rich Repeat F-box-like_2 PF13013.1 EMG47119.1 - 0.088 12.5 0.2 2.1 8.0 0.0 2.8 3 0 0 3 3 3 0 F-box-like domain LRR_6 PF13516.1 EMG47119.1 - 2.1 8.6 37.2 5.5 7.3 1.1 9.5 11 0 0 11 11 11 0 Leucine Rich repeat SQS_PSY PF00494.14 EMG47120.1 - 9.8e-44 149.6 0.0 1.2e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF544 PF04424.8 EMG47121.1 - 1.6e-13 50.4 1.1 3.1e-13 49.5 0.5 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF544) Parathyroid PF01279.12 EMG47121.1 - 0.67 10.6 7.6 1.9 9.2 5.3 1.7 1 0 0 1 1 1 0 Parathyroid hormone family Paf1 PF03985.8 EMG47122.1 - 6.8e-93 311.7 8.4 8.3e-93 311.4 5.8 1.0 1 0 0 1 1 1 1 Paf1 Flocculin_t3 PF13928.1 EMG47123.1 - 2.4e-19 69.2 66.0 7.5e-14 51.6 11.5 6.5 6 0 0 6 6 6 3 Flocculin type 3 repeat DUF3464 PF11947.3 EMG47123.1 - 0.23 10.8 2.8 0.28 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) Nop14 PF04147.7 EMG47123.1 - 9.3 4.0 18.6 13 3.5 12.9 1.1 1 0 0 1 1 1 0 Nop14-like family Gtr1_RagA PF04670.7 EMG47124.1 - 3.8e-92 307.6 3.6 5.5e-92 307.1 2.5 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EMG47124.1 - 8.4e-08 31.6 0.1 8.4e-08 31.6 0.1 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 EMG47124.1 - 2.1e-07 31.4 0.4 5.3e-07 30.1 0.1 1.9 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 EMG47124.1 - 3.3e-07 29.8 0.2 6.6e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 EMG47124.1 - 4.6e-06 26.5 0.2 1.2e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF815 PF05673.8 EMG47124.1 - 0.015 14.2 0.1 0.03 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 EMG47124.1 - 0.021 15.1 0.3 0.021 15.1 0.2 2.0 2 2 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 EMG47124.1 - 0.041 13.4 2.2 0.063 12.8 0.7 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EMG47124.1 - 0.11 12.6 1.2 2.2 8.4 0.2 2.9 2 1 0 2 2 2 0 AAA domain DUF1033 PF06279.6 EMG47124.1 - 0.14 11.9 1.5 0.32 10.8 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1033) AAA_14 PF13173.1 EMG47124.1 - 0.7 9.7 6.1 3.9 7.3 1.5 2.9 2 2 0 2 2 2 0 AAA domain CUE PF02845.11 EMG47126.1 - 5.3e-05 22.6 0.0 0.0001 21.6 0.0 1.5 1 0 0 1 1 1 1 CUE domain Adap_comp_sub PF00928.16 EMG47127.1 - 3.3e-76 255.8 0.5 4.1e-76 255.5 0.3 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EMG47127.1 - 0.0012 18.5 0.6 0.0024 17.5 0.4 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Flocculin_t3 PF13928.1 EMG47128.1 - 1.9e-32 111.1 72.9 1.4e-14 53.8 12.4 7.0 5 1 1 6 6 6 3 Flocculin type 3 repeat Flocculin_t3 PF13928.1 EMG47129.1 - 8.3e-46 153.8 185.2 1e-12 47.9 11.8 16.2 12 4 3 15 15 15 9 Flocculin type 3 repeat DUF1839 PF08893.5 EMG47129.1 - 0.17 10.7 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1839) Anp1 PF03452.9 EMG47130.1 - 1.4e-120 401.5 0.0 1.9e-120 401.0 0.0 1.2 1 0 0 1 1 1 1 Anp1 COX4_pro_2 PF07835.7 EMG47130.1 - 0.39 10.7 2.5 5.2 7.1 2.1 2.1 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV SMC_N PF02463.14 EMG47131.1 - 1.2e-60 204.5 40.2 2.2e-57 193.7 27.8 3.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EMG47131.1 - 1.7e-19 69.9 0.3 1.7e-19 69.9 0.2 2.5 2 1 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EMG47131.1 - 3.2e-08 34.1 42.9 3.2e-08 34.1 29.7 7.1 2 2 4 6 6 6 1 AAA domain AAA_21 PF13304.1 EMG47131.1 - 1.4e-06 28.5 19.6 0.00014 21.9 5.0 5.6 2 2 2 5 5 5 2 AAA domain AAA_29 PF13555.1 EMG47131.1 - 3.3e-05 23.3 0.1 8.2e-05 22.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 EMG47131.1 - 7.1e-05 20.3 15.4 7.1e-05 20.3 10.7 4.1 2 2 2 4 4 4 1 Protein of unknown function (DUF3584) Tropomyosin_1 PF12718.2 EMG47131.1 - 0.0021 17.9 28.5 0.0021 17.9 19.7 7.7 2 2 6 9 9 9 3 Tropomyosin like IncA PF04156.9 EMG47131.1 - 0.0025 17.4 21.9 0.0025 17.4 15.2 8.0 2 2 7 9 9 9 3 IncA protein Myosin_tail_1 PF01576.14 EMG47131.1 - 0.65 7.6 116.1 0.017 12.9 26.7 3.3 3 0 0 3 3 3 0 Myosin tail Reo_sigmaC PF04582.7 EMG47131.1 - 0.84 8.7 50.9 0.06 12.5 4.7 6.7 3 2 4 8 8 8 0 Reovirus sigma C capsid protein Gly-zipper_YMGG PF13441.1 EMG47132.1 - 0.0046 16.4 4.5 0.041 13.4 3.2 2.1 1 1 0 1 1 1 1 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 EMG47132.1 - 0.014 15.0 12.5 0.25 10.9 8.7 2.2 1 1 0 1 1 1 0 Glycine zipper SseC PF04888.7 EMG47132.1 - 0.018 14.4 3.0 0.022 14.0 2.1 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Transgly_assoc PF04226.8 EMG47132.1 - 0.35 10.9 18.1 1.5e+03 -0.7 12.5 3.1 1 1 0 1 1 1 0 Transglycosylase associated protein Rick_17kDa_Anti PF05433.10 EMG47132.1 - 0.6 9.8 8.6 8.7 6.1 6.0 2.3 1 1 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 EMG47132.1 - 0.94 9.1 14.0 3.7 7.2 9.7 1.8 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain FMN_red PF03358.10 EMG47133.1 - 1.4e-10 40.8 0.0 1.9e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EMG47133.1 - 1.8e-05 24.3 0.0 2.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.20 EMG47133.1 - 2.1e-05 24.5 0.0 3.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin FBA_2 PF07735.12 EMG47134.1 - 0.21 11.4 0.5 0.63 9.9 0.1 1.8 1 1 1 2 2 2 0 F-box associated Lectin_leg-like PF03388.8 EMG47135.1 - 2.6e-49 167.4 0.0 3.5e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EMG47135.1 - 6.6e-06 25.6 0.0 0.00086 18.7 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain DUF4407 PF14362.1 EMG47135.1 - 0.0071 15.3 0.7 0.012 14.6 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) MRP-S26 PF14943.1 EMG47135.1 - 0.028 13.9 6.5 0.056 12.9 4.5 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 BHD_2 PF10404.4 EMG47135.1 - 0.045 14.0 1.8 0.11 12.8 1.2 1.6 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 2 DUF3671 PF12420.3 EMG47135.1 - 0.74 9.8 4.9 0.3 11.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function Pho86 PF11124.3 EMG47136.1 - 1.1e-116 389.0 1.5 1.3e-116 388.8 1.0 1.0 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 FMO-like PF00743.14 EMG47137.1 - 1.2e-31 109.5 4.8 2.2e-13 49.2 0.1 3.0 1 1 2 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EMG47137.1 - 8e-15 55.4 1.0 4.7e-14 52.9 0.6 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMG47137.1 - 2.1e-11 43.3 1.8 1.2e-06 27.6 0.1 3.3 2 1 2 4 4 4 3 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EMG47137.1 - 4.7e-09 36.2 0.3 3.4e-08 33.4 0.2 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMG47137.1 - 5.4e-07 29.6 0.0 2.3e-06 27.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMG47137.1 - 0.00019 20.4 0.0 0.15 10.9 0.0 3.0 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMG47137.1 - 0.00023 21.1 0.0 0.00061 19.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EMG47137.1 - 0.02 15.0 0.1 0.59 10.2 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EMG47137.1 - 0.029 14.7 0.5 6.2 7.2 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Semialdhyde_dh PF01118.19 EMG47137.1 - 0.032 14.5 0.0 5.3 7.3 0.0 2.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Phage_GPA PF05840.8 EMG47137.1 - 0.061 12.0 0.2 0.061 12.0 0.2 1.7 1 1 1 2 2 2 0 Bacteriophage replication gene A protein (GPA) UPF0370 PF13980.1 EMG47137.1 - 5.1 7.0 6.6 16 5.4 0.7 3.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0370) SLAC1 PF03595.12 EMG47138.1 - 1.8e-73 247.0 38.2 2.1e-73 246.8 26.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Abhydro_lipase PF04083.11 EMG47140.1 - 2.1e-20 71.8 0.0 4.2e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EMG47140.1 - 3.6e-06 26.6 1.7 0.0017 17.9 0.0 3.0 2 1 1 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMG47140.1 - 2.8e-05 23.8 0.0 7.6e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMG47140.1 - 0.00024 21.0 0.0 0.00051 20.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.3 EMG47140.1 - 0.013 14.6 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) IU_nuc_hydro PF01156.14 EMG47141.1 - 1.6e-80 270.6 0.0 1.8e-80 270.4 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase His_Phos_1 PF00300.17 EMG47142.1 - 3.6e-33 114.8 0.1 4.3e-33 114.6 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RTC PF01137.16 EMG47144.1 - 3e-57 193.0 0.0 3.6e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EMG47144.1 - 1.1e-31 108.9 0.0 1.8e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain MBOAT PF03062.14 EMG47145.1 - 1.9e-56 191.5 9.8 1.9e-56 191.5 6.8 2.0 3 0 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family Cnd1 PF12717.2 EMG47146.1 - 1.8e-49 167.9 16.1 4.2e-49 166.8 0.4 4.8 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 EMG47146.1 - 1.7e-44 151.4 2.8 5.6e-44 149.7 0.0 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 EMG47146.1 - 4.9e-10 39.5 0.4 0.015 15.5 0.2 4.8 3 3 1 4 4 4 3 HEAT repeats HEAT PF02985.17 EMG47146.1 - 1.9e-06 27.4 6.8 1.5 9.0 0.0 5.9 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EMG47146.1 - 2e-05 24.9 2.2 0.31 11.5 0.0 5.5 6 1 1 7 7 7 1 HEAT-like repeat Cnd3 PF12719.2 EMG47146.1 - 0.012 14.5 5.8 0.011 14.7 0.9 2.8 2 1 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain EF-hand_6 PF13405.1 EMG47146.1 - 0.066 13.1 3.6 0.58 10.1 0.3 3.0 2 0 0 2 2 2 0 EF-hand domain TAF4 PF05236.9 EMG47147.1 - 2.5e-79 266.2 1.9 4.3e-79 265.5 1.3 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family NDUF_B8 PF05821.6 EMG47148.1 - 8.2e-09 35.3 0.2 1.2e-08 34.8 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Pkinase PF00069.20 EMG47150.1 - 8e-59 198.8 0.0 1.1e-58 198.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG47150.1 - 1.7e-31 109.2 0.0 2.3e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EMG47150.1 - 7.2e-14 51.6 0.3 1.8e-13 50.3 0.2 1.8 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EMG47150.1 - 1.1e-05 24.6 0.0 4.1e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMG47150.1 - 0.074 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RRM_1 PF00076.17 EMG47151.1 - 8.1e-32 108.6 0.0 1.7e-11 43.6 0.1 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG47151.1 - 2.6e-16 59.3 0.0 0.00031 20.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG47151.1 - 1.9e-12 46.8 0.2 0.00012 21.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMG47151.1 - 0.031 14.1 0.0 0.081 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA binding motif Med4 PF10018.4 EMG47152.1 - 5.9e-38 130.1 11.2 5.9e-38 130.1 7.8 2.0 1 1 1 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 THOC7 PF05615.8 EMG47152.1 - 0.14 12.3 8.0 0.03 14.5 2.4 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 Med9 PF07544.8 EMG47152.1 - 0.15 11.8 4.1 0.49 10.1 0.1 3.0 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 bZIP_1 PF00170.16 EMG47152.1 - 0.15 11.9 7.9 1.2 9.1 0.1 3.0 1 1 2 3 3 3 0 bZIP transcription factor DUF904 PF06005.7 EMG47152.1 - 4.7 7.5 15.2 0.11 12.8 3.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Ferrochelatase PF00762.14 EMG47153.1 - 1.7e-72 244.1 0.0 1.8e-72 243.9 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase SNF2_N PF00176.18 EMG47154.1 - 3.1e-75 252.7 1.2 3.1e-75 252.7 0.8 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain HSA PF07529.8 EMG47154.1 - 4.3e-10 39.2 7.6 4.3e-10 39.2 5.3 3.9 4 0 0 4 4 4 1 HSA DEAD PF00270.24 EMG47154.1 - 6.6e-06 25.7 0.0 2e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3112 PF11309.3 EMG47156.1 - 6.2e-30 104.1 3.6 6.2e-30 104.1 2.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3112) DUF3112 PF11309.3 EMG47157.1 - 5.8e-07 29.4 2.0 7.8e-07 29.0 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3112) TSP_C PF05735.7 EMG47157.1 - 0.22 11.0 1.2 0.27 10.7 0.8 1.1 1 0 0 1 1 1 0 Thrombospondin C-terminal region Imm5 PF14423.1 EMG47157.1 - 0.57 9.7 2.5 0.81 9.2 1.7 1.3 1 0 0 1 1 1 0 Immunity protein Imm5 Zn_clus PF00172.13 EMG47158.1 - 0.00021 21.1 7.4 0.00043 20.1 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HALZ PF02183.13 EMG47158.1 - 0.43 10.3 8.8 0.21 11.3 3.1 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper DJ-1_PfpI PF01965.19 EMG47159.1 - 1.5e-22 79.6 0.1 2.4e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EMG47159.1 - 0.00037 19.9 0.0 0.001 18.5 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of DJ-1_PfpI family SpoIISB_antitox PF14185.1 EMG47159.1 - 0.11 12.3 0.7 0.98 9.2 0.1 2.2 2 0 0 2 2 2 0 Antitoxin SpoIISB, type II toxin-antitoxin system DJ-1_PfpI PF01965.19 EMG47160.1 - 1.3e-24 86.3 0.1 2.7e-24 85.3 0.1 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EMG47160.1 - 0.00015 21.2 0.0 0.00038 19.9 0.0 1.8 1 1 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DUF4241 PF14025.1 EMG47160.1 - 0.045 13.5 0.0 0.079 12.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4241) MPC PF03650.8 EMG47161.1 - 3.4e-38 130.2 0.1 4.2e-38 129.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Flocculin_t3 PF13928.1 EMG47162.1 - 4.7e-14 52.2 88.4 1.7e-08 34.4 13.9 15.9 9 5 5 14 14 14 4 Flocculin type 3 repeat TLD PF07534.11 EMG47163.1 - 1.2e-25 90.1 1.3 2.4e-21 76.1 0.2 2.5 1 1 1 2 2 2 2 TLD Asp_Glu_race PF01177.17 EMG47164.1 - 4.8e-24 85.4 0.0 5.4e-24 85.2 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase DUF2183 PF09949.4 EMG47164.1 - 0.055 13.3 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) Rad9 PF04139.8 EMG47165.1 - 4.4e-15 55.4 8.2 4.7e-14 52.1 5.7 2.3 1 1 0 1 1 1 1 Rad9 Metallopep PF12044.3 EMG47166.1 - 6.1e-159 529.0 0.0 7.4e-159 528.7 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 EMG47166.1 - 9.6e-07 28.7 0.0 2.3e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_5 PF13688.1 EMG47166.1 - 0.00051 20.0 0.7 0.001 19.0 0.5 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EMG47166.1 - 0.044 14.3 0.1 0.1 13.0 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like XPA_C PF05181.7 EMG47167.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 XPA protein C-terminus Adaptin_N PF01602.15 EMG47168.1 - 8.5e-99 331.2 19.7 1.5e-98 330.4 13.7 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EMG47168.1 - 6.1e-10 39.2 17.2 2.2e-09 37.4 3.7 3.2 3 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Acyltransferase PF01553.16 EMG47169.1 - 9.4e-33 112.4 0.0 1.4e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DJ-1_PfpI PF01965.19 EMG47170.1 - 1.4e-20 73.2 0.0 2.2e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EMG47170.1 - 0.044 13.3 0.0 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 N-terminal domain of DJ-1_PfpI family Flocculin_t3 PF13928.1 EMG47171.1 - 5.8e-08 32.7 30.4 5.8e-08 32.7 21.1 5.6 5 1 0 5 5 5 1 Flocculin type 3 repeat Flocculin_t3 PF13928.1 EMG47172.1 - 2.8e-12 46.5 25.8 2.8e-12 46.5 17.9 2.9 3 0 0 3 3 3 1 Flocculin type 3 repeat Acid_PPase PF12689.2 EMG47173.1 - 4.7e-52 176.0 0.0 5.3e-52 175.8 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase NIF PF03031.13 EMG47173.1 - 0.00058 19.5 0.0 0.00071 19.2 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2070 PF09843.4 EMG47173.1 - 0.05 13.0 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ADH_zinc_N PF00107.21 EMG47175.1 - 1.7e-29 102.0 0.0 3.2e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMG47175.1 - 4.6e-13 50.1 0.0 9.5e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMG47175.1 - 2.8e-11 43.1 0.0 5.4e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CdhD PF03599.11 EMG47175.1 - 0.0019 16.7 0.0 0.0028 16.1 0.0 1.2 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit NAD_binding_10 PF13460.1 EMG47175.1 - 0.073 13.0 0.3 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 NADH(P)-binding Cpn10 PF00166.16 EMG47175.1 - 0.078 12.9 0.7 0.64 9.9 0.0 2.5 2 1 0 2 2 2 0 Chaperonin 10 Kd subunit DUF208 PF02677.9 EMG47175.1 - 0.15 11.8 0.0 0.34 10.6 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized BCR, COG1636 Cyt-b5 PF00173.23 EMG47176.1 - 4e-14 52.1 0.0 1.1e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 EMG47176.1 - 8.5e-11 41.7 8.5 1.9e-10 40.6 5.9 1.6 1 1 0 1 1 1 1 Fatty acid desaturase MRF_C1 PF13887.1 EMG47176.1 - 0.034 13.1 0.3 0.16 11.0 0.0 2.0 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 DUF3671 PF12420.3 EMG47176.1 - 0.33 10.9 6.7 13 5.8 2.6 2.6 2 0 0 2 2 2 0 Protein of unknown function SNF2_N PF00176.18 EMG47177.1 - 5.2e-41 140.3 0.1 1.7e-19 69.7 0.1 2.5 2 0 0 2 2 2 2 SNF2 family N-terminal domain zf-RING_2 PF13639.1 EMG47177.1 - 1.8e-08 34.0 16.2 4.8e-08 32.6 11.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMG47177.1 - 3.3e-07 29.8 14.2 6.4e-07 28.9 9.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMG47177.1 - 1.7e-06 27.5 16.8 4.6e-06 26.1 11.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMG47177.1 - 2e-05 24.5 16.4 4.8e-05 23.3 11.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMG47177.1 - 3.4e-05 23.8 7.8 0.00011 22.2 5.4 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EMG47177.1 - 0.0006 19.4 15.7 0.0013 18.4 10.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EMG47177.1 - 0.0018 17.8 4.6 0.0072 15.8 3.2 2.0 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Helicase_C PF00271.26 EMG47177.1 - 0.0039 17.0 0.0 0.0098 15.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.1 EMG47177.1 - 0.043 13.5 12.2 0.11 12.1 8.4 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 EMG47177.1 - 0.052 13.0 8.2 0.11 12.0 5.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 EMG47177.1 - 0.42 10.4 7.6 1.1 9.1 5.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EMG47177.1 - 0.59 10.0 13.3 1.6 8.6 9.2 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 EMG47177.1 - 3 7.3 11.7 7.6 6.0 8.1 1.6 1 0 0 1 1 1 0 P-11 zinc finger tRNA_anti-codon PF01336.20 EMG47178.1 - 0.00025 20.8 0.1 0.0004 20.1 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SWIB PF02201.13 EMG47180.1 - 9.4e-06 25.2 1.5 0.00088 18.9 0.1 2.8 2 1 0 2 2 2 2 SWIB/MDM2 domain DUF3112 PF11309.3 EMG47181.1 - 4.5e-13 49.2 1.3 5.6e-13 48.9 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3112) DUF3112 PF11309.3 EMG47182.1 - 2.1e-09 37.3 4.1 2.6e-09 37.0 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3112) DUF1730 PF08331.5 EMG47182.1 - 0.062 12.9 0.1 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) Ebola_NP PF05505.7 EMG47182.1 - 6.2 4.7 7.3 7.3 4.5 5.0 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein DUF1682 PF07946.9 EMG47183.1 - 2.3e-89 299.4 9.6 2.3e-89 299.4 6.6 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1682) Ank_5 PF13857.1 EMG47183.1 - 4.4e-16 58.5 0.1 1.3e-12 47.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMG47183.1 - 5.1e-13 49.1 0.1 1.2e-12 47.9 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMG47183.1 - 6.3e-11 42.4 0.1 4.8e-09 36.4 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EMG47183.1 - 1.1e-10 40.8 2.3 1.1e-09 37.6 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 EMG47183.1 - 1.4e-10 40.3 0.9 6.1e-07 29.0 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat AAA_23 PF13476.1 EMG47183.1 - 2.6 8.3 23.0 5.5 7.2 2.6 2.6 2 0 0 2 2 2 0 AAA domain Stk19 PF10494.4 EMG47184.1 - 6.4e-75 251.7 0.3 6.4e-75 251.7 0.2 1.5 2 0 0 2 2 2 1 Serine-threonine protein kinase 19 DREPP PF05558.7 EMG47184.1 - 0.32 10.8 3.5 2.7 7.7 0.6 2.1 2 0 0 2 2 2 0 DREPP plasma membrane polypeptide Ribosomal_L9_N PF01281.14 EMG47185.1 - 6.6e-16 57.2 0.0 1.4e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain DUF3839 PF12943.2 EMG47185.1 - 0.13 11.4 0.7 0.4 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3839) zf-HIT PF04438.11 EMG47186.1 - 3.9e-09 36.0 9.9 5.6e-09 35.4 6.8 1.2 1 0 0 1 1 1 1 HIT zinc finger Nop14 PF04147.7 EMG47186.1 - 0.42 8.4 11.8 0.024 12.6 4.5 1.5 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.9 EMG47186.1 - 2.1 6.2 10.2 0.076 11.0 3.0 1.5 2 0 0 2 2 2 0 CDC45-like protein Prp19_bind PF06991.6 EMG47186.1 - 4.2 6.5 11.7 0.52 9.5 5.1 1.6 2 0 0 2 2 2 0 Splicing factor, Prp19-binding domain Sigma70_ner PF04546.8 EMG47186.1 - 4.4 6.8 8.3 8.5 5.9 5.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Tnp_zf-ribbon_2 PF13842.1 EMG47186.1 - 6.1 7.3 10.6 12 6.3 7.3 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon BUD22 PF09073.5 EMG47186.1 - 8.6 5.3 13.9 0.68 8.9 6.1 1.6 2 0 0 2 2 2 0 BUD22 RRM_1 PF00076.17 EMG47187.1 - 3.2e-17 61.9 0.0 5e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG47187.1 - 6.2e-09 35.5 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG47187.1 - 7.8e-09 35.3 0.0 1.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMG47187.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ZZ PF00569.12 EMG47188.1 - 1.5e-07 30.7 9.7 4.6e-07 29.2 6.7 1.9 1 0 0 1 1 1 1 Zinc finger, ZZ type Asp PF00026.18 EMG47189.1 - 8e-90 301.2 13.9 9.2e-90 301.0 9.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EMG47189.1 - 2.7e-06 27.0 0.0 0.00048 19.7 0.0 2.6 3 0 0 3 3 3 2 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EMG47189.1 - 9e-05 22.4 1.7 9e-05 22.4 1.2 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMG47189.1 - 0.027 14.9 5.6 4.3 7.8 0.9 3.7 2 2 1 3 3 3 0 Aspartyl protease DUF3112 PF11309.3 EMG47190.1 - 1.2e-49 168.1 9.3 1.2e-49 168.1 6.4 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3112) Abhydrolase_1 PF00561.15 EMG47191.1 - 1.2e-13 51.1 0.0 2.2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMG47191.1 - 1.5e-07 31.5 0.0 1.7e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMG47191.1 - 0.00011 21.9 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMG47191.1 - 0.0049 16.1 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EMG47191.1 - 0.11 12.4 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_8 PF06259.7 EMG47191.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase A_deaminase PF00962.17 EMG47192.1 - 2.9e-81 272.9 0.0 3.3e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF1399 PF07173.7 EMG47193.1 - 8.5e-06 26.1 0.2 8.5e-06 26.1 0.2 3.5 2 1 2 4 4 4 2 Protein of unknown function (DUF1399) BAR PF03114.13 EMG47194.1 - 0.00034 20.1 8.8 0.00075 19.0 5.8 1.7 1 1 0 1 1 1 1 BAR domain Seryl_tRNA_N PF02403.17 EMG47194.1 - 0.0046 16.9 3.6 0.11 12.5 2.2 2.8 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DUF342 PF03961.8 EMG47194.1 - 0.73 8.1 4.6 1.5 7.1 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SBDS PF01172.13 EMG47195.1 - 4.3e-18 64.9 0.4 5.4e-18 64.5 0.3 1.2 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein RhoGEF PF00621.15 EMG47196.1 - 4.4e-11 42.9 2.7 8.6e-11 42.0 1.9 1.6 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 EMG47196.1 - 0.0083 16.3 0.5 0.026 14.6 0.1 2.1 2 0 0 2 2 2 1 PH domain Aldedh PF00171.17 EMG47197.1 - 1.1e-125 419.6 0.0 1.6e-125 419.0 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Tcf25 PF04910.9 EMG47197.1 - 1.2e-97 327.1 4.8 2.2e-97 326.2 3.3 1.5 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Peptidase_C37 PF05416.7 EMG47197.1 - 0.37 9.0 9.3 0.63 8.2 6.4 1.3 1 0 0 1 1 1 0 Southampton virus-type processing peptidase V-ATPase_G PF03179.10 EMG47198.1 - 9.3e-30 103.0 10.9 1e-29 102.9 7.5 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 EMG47198.1 - 0.00059 19.6 13.0 0.0066 16.2 5.6 2.0 1 1 1 2 2 2 2 ATP synthase B/B' CF(0) DUF3552 PF12072.3 EMG47198.1 - 0.0022 17.2 11.4 0.0031 16.7 7.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) vATP-synt_E PF01991.13 EMG47198.1 - 0.011 15.0 9.9 0.014 14.6 6.9 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit DUF89 PF01937.14 EMG47198.1 - 0.037 12.8 1.7 0.042 12.6 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF89 RRF PF01765.14 EMG47198.1 - 0.038 13.4 10.5 0.05 13.0 7.3 1.2 1 0 0 1 1 1 0 Ribosome recycling factor DUF3496 PF12001.3 EMG47198.1 - 0.064 13.5 3.7 0.075 13.2 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) YgaB PF14182.1 EMG47198.1 - 0.076 13.2 6.1 0.06 13.5 3.0 1.7 1 1 0 1 1 1 0 YgaB-like protein GA PF01468.12 EMG47198.1 - 0.15 12.1 5.7 0.13 12.4 2.8 1.9 1 1 0 1 1 1 0 GA module Cytochrom_B562 PF07361.6 EMG47198.1 - 0.32 11.4 7.3 0.45 10.9 5.1 1.3 1 1 0 1 1 1 0 Cytochrome b562 OmpH PF03938.9 EMG47198.1 - 0.32 10.9 9.1 0.4 10.5 6.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.7 EMG47198.1 - 0.46 10.2 13.0 2 8.1 7.4 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.1 EMG47198.1 - 0.5 9.2 6.6 0.65 8.8 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mt_ATP-synt_D PF05873.7 EMG47198.1 - 0.89 9.1 7.5 0.73 9.4 4.1 1.5 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Potyvirid-P3 PF13608.1 EMG47198.1 - 1.7 7.7 6.4 2 7.4 4.4 1.0 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein APG6 PF04111.7 EMG47198.1 - 1.7 7.5 9.0 2.1 7.3 6.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EMG47198.1 - 3 7.4 5.9 3.9 7.0 4.1 1.2 1 0 0 1 1 1 0 IncA protein MBOAT PF03062.14 EMG47199.1 - 1.2e-40 139.6 30.1 2.6e-39 135.2 11.5 2.5 2 1 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EMG47199.1 - 0.00052 20.0 1.5 0.0014 18.6 1.0 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family GP40 PF11025.3 EMG47199.1 - 1.3 8.5 6.7 2.3 7.7 4.6 1.3 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium Peptidase_M76 PF09768.4 EMG47200.1 - 3.8e-72 241.3 1.7 5e-72 240.9 1.2 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 EMG47200.1 - 0.21 11.2 2.6 0.17 11.5 0.2 1.8 1 1 1 2 2 2 0 SprT-like family Spermine_synth PF01564.12 EMG47201.1 - 8e-101 336.0 0.0 1.3e-100 335.4 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 EMG47201.1 - 4.8e-05 22.9 0.0 7.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMG47201.1 - 0.0029 18.0 0.0 0.0069 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMG47201.1 - 0.0089 16.5 0.0 0.022 15.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_30 PF05430.6 EMG47201.1 - 0.024 14.3 0.0 0.067 12.8 0.0 1.7 1 1 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 EMG47201.1 - 0.061 12.6 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF43 PF01861.11 EMG47201.1 - 0.093 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF43 Methyltransf_15 PF09445.5 EMG47202.1 - 5.6e-47 159.3 0.0 8.1e-47 158.8 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EMG47202.1 - 2.6e-09 37.1 0.0 6.1e-09 35.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMG47202.1 - 0.00015 21.4 0.1 0.00076 19.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMG47202.1 - 0.00034 20.9 0.0 0.00072 19.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMG47202.1 - 0.00037 21.0 0.0 0.001 19.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain N6_Mtase PF02384.11 EMG47202.1 - 0.0016 17.5 0.7 0.0047 16.0 0.0 2.1 2 1 0 2 2 2 1 N-6 DNA Methylase Nol1_Nop2_Fmu PF01189.12 EMG47202.1 - 0.0054 16.1 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family MTS PF05175.9 EMG47202.1 - 0.0067 15.8 0.1 0.095 12.0 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EMG47202.1 - 0.038 13.5 0.1 0.14 11.7 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EMG47202.1 - 0.039 14.4 0.1 0.21 12.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.13 EMG47202.1 - 0.12 11.4 0.0 0.61 9.1 0.0 1.9 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family DUF1754 PF08555.5 EMG47202.1 - 0.46 11.1 23.4 0.16 12.5 4.8 2.3 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) DUF1510 PF07423.6 EMG47202.1 - 3.3 7.0 24.5 1.1 8.6 7.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF2439 PF10382.4 EMG47204.1 - 1.6e-23 82.6 2.0 1.6e-23 82.6 1.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2439) Ribosomal_L5_C PF00673.16 EMG47205.1 - 1.1e-23 82.8 0.0 1.4e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus GLE1 PF07817.8 EMG47206.1 - 9.6e-85 283.5 2.0 9.6e-85 283.5 1.4 2.9 3 1 0 3 3 3 1 GLE1-like protein DUF948 PF06103.6 EMG47206.1 - 1.9 8.4 6.1 0.96 9.3 1.7 2.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1777 PF08648.7 EMG47206.1 - 3.7 7.2 40.6 6.4 6.4 28.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) HEAT_2 PF13646.1 EMG47207.1 - 3.6e-09 36.7 0.0 0.00017 21.8 0.0 4.1 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.17 EMG47207.1 - 5.7e-07 29.0 0.1 1.2 9.4 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat CLASP_N PF12348.3 EMG47207.1 - 0.0001 21.7 1.9 0.6 9.4 0.0 3.8 4 0 0 4 4 4 2 CLASP N terminal HEAT_EZ PF13513.1 EMG47207.1 - 0.0027 18.1 0.0 1.5 9.4 0.0 4.1 4 0 0 4 4 4 1 HEAT-like repeat NST1 PF13945.1 EMG47208.1 - 2.4e-12 47.3 13.6 3.5e-08 33.7 6.3 8.9 6 3 2 10 10 10 3 Salt tolerance down-regulator Ras PF00071.17 EMG47209.1 - 1.4e-48 164.3 0.0 1.6e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMG47209.1 - 8.7e-16 58.4 0.0 1.2e-15 58.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMG47209.1 - 7.2e-06 25.3 0.0 1e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 EMG47209.1 - 0.0024 17.3 0.0 1.9 7.9 0.0 2.2 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EMG47209.1 - 0.055 12.6 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit EamA PF00892.15 EMG47210.1 - 1.1e-25 90.0 34.3 1e-16 61.1 6.6 2.4 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EMG47210.1 - 6.7e-08 32.7 9.1 6.7e-08 32.7 6.3 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter Cation_ATPase_C PF00689.16 EMG47210.1 - 2.1 7.8 21.0 0.49 9.8 9.4 3.3 1 1 1 3 3 3 0 Cation transporting ATPase, C-terminus MobC PF05713.6 EMG47211.1 - 0.0015 18.4 2.2 0.0029 17.5 1.5 1.5 1 0 0 1 1 1 1 Bacterial mobilisation protein (MobC) Spc7 PF08317.6 EMG47211.1 - 0.0016 17.1 0.4 0.0018 17.0 0.3 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein BLOC1_2 PF10046.4 EMG47211.1 - 0.37 10.9 5.1 0.54 10.4 3.5 1.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LOH1CR12 PF10158.4 EMG47213.1 - 0.056 13.2 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Tumour suppressor protein GCR1_C PF12550.3 EMG47214.1 - 1.6e-22 79.1 0.4 3.2e-22 78.1 0.3 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes PAT1 PF09770.4 EMG47214.1 - 0.0022 16.3 34.3 0.0025 16.1 23.8 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 IncA PF04156.9 EMG47214.1 - 0.01 15.4 4.1 0.01 15.4 2.8 2.8 1 1 1 2 2 2 0 IncA protein DUF2422 PF10337.4 EMG47214.1 - 1.7 7.3 15.4 2.2 6.9 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Peptidase_S46 PF10459.4 EMG47214.1 - 2 6.7 20.2 2.7 6.3 14.0 1.2 1 0 0 1 1 1 0 Peptidase S46 Med15 PF09606.5 EMG47214.1 - 3.1 5.8 53.7 4.2 5.4 37.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal GAGA_bind PF06217.7 EMG47214.1 - 7.7 6.3 21.0 13 5.6 14.6 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family FMN_red PF03358.10 EMG47215.1 - 1.8e-10 40.5 0.0 2.5e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 EMG47215.1 - 2.2e-05 24.4 0.0 3.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 EMG47215.1 - 2.8e-05 23.7 0.0 3.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Peptidase_S8 PF00082.17 EMG47216.1 - 7.2e-47 159.8 5.2 9.9e-47 159.4 3.6 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMG47216.1 - 2e-11 44.2 0.3 3.9e-11 43.3 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Aldo_ket_red PF00248.16 EMG47217.1 - 8.4e-39 133.0 0.1 1.2e-38 132.6 0.1 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family LsmAD PF06741.8 EMG47217.1 - 0.14 12.2 0.5 0.35 10.9 0.1 1.8 2 0 0 2 2 2 0 LsmAD domain Abhydrolase_6 PF12697.2 EMG47218.1 - 1.7e-13 50.9 0.0 2.6e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMG47218.1 - 2.3e-11 43.7 0.0 4.5e-11 42.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMG47218.1 - 1.5e-06 28.0 0.0 4.9e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EMG47218.1 - 9.8e-05 22.1 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_9 PF10081.4 EMG47218.1 - 0.025 13.3 0.0 0.043 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Peptidase_S15 PF02129.13 EMG47218.1 - 0.026 13.9 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Lipase_3 PF01764.20 EMG47218.1 - 0.033 13.8 0.0 0.075 12.6 0.0 1.7 1 1 0 1 1 1 0 Lipase (class 3) VirJ PF06057.6 EMG47218.1 - 0.053 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_2 PF02230.11 EMG47218.1 - 0.073 12.4 0.0 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF4604 PF15377.1 EMG47218.1 - 0.14 12.3 0.3 0.23 11.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Asp PF00026.18 EMG47219.1 - 8.4e-104 347.2 0.3 1e-103 346.9 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMG47219.1 - 6.4e-10 39.2 0.0 1.3e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMG47219.1 - 5e-06 26.9 0.0 0.0062 17.0 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EMG47219.1 - 0.00012 21.6 0.0 0.0013 18.2 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal HSP70 PF00012.15 EMG47221.1 - 1.5e-264 878.5 14.4 1.7e-264 878.3 10.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMG47221.1 - 2e-15 56.2 6.1 8.5e-14 50.8 2.8 2.4 2 0 0 2 2 2 2 MreB/Mbl protein Gp-FAR-1 PF05823.7 EMG47221.1 - 0.00057 19.8 3.8 0.0016 18.3 2.6 1.7 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) FGGY_C PF02782.11 EMG47221.1 - 0.00093 18.8 0.0 0.0031 17.1 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EMG47221.1 - 0.0046 16.7 12.2 0.91 9.3 0.1 4.4 3 2 0 3 3 3 2 Cell division protein FtsA Holin_LLH PF09682.5 EMG47221.1 - 0.69 10.0 5.1 2.3 8.3 0.1 3.0 2 0 0 2 2 2 0 Phage holin protein (Holin_LLH) Hydantoinase_A PF01968.13 EMG47221.1 - 1.1 8.3 9.5 1.1 8.2 0.2 3.6 2 1 2 4 4 4 0 Hydantoinase/oxoprolinase CYSTM PF12734.2 EMG47222.1 - 0.047 13.7 63.8 1.5e+04 -4.6 44.2 4.0 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance Extensin_2 PF04554.8 EMG47222.1 - 0.13 12.1 18.3 0.16 11.8 12.7 1.1 1 0 0 1 1 1 0 Extensin-like region Pro-rich PF15240.1 EMG47222.1 - 0.44 10.6 16.2 0.52 10.3 11.2 1.1 1 0 0 1 1 1 0 Proline-rich SMC_N PF02463.14 EMG47223.1 - 1.1e-47 162.0 73.8 1.1e-46 158.7 51.2 3.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EMG47223.1 - 6.5e-29 100.3 0.1 6.5e-29 100.3 0.1 2.5 2 1 1 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EMG47223.1 - 4e-14 53.4 23.5 4e-14 53.4 16.3 7.2 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.1 EMG47223.1 - 1.5e-09 38.2 45.6 1.6e-08 34.8 4.4 4.9 2 2 0 3 3 3 2 AAA domain GAS PF13851.1 EMG47223.1 - 0.00077 18.7 7.2 0.00077 18.7 5.0 8.2 4 2 4 8 8 8 1 Growth-arrest specific micro-tubule binding AAA_29 PF13555.1 EMG47223.1 - 0.0014 18.1 0.0 0.0029 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 EMG47223.1 - 1.5 6.0 101.2 0.032 11.5 32.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) CTP_transf_1 PF01148.15 EMG47224.1 - 0.00014 21.6 23.8 0.00014 21.6 16.5 3.2 1 1 2 3 3 3 1 Cytidylyltransferase family FA_desaturase PF00487.19 EMG47225.1 - 3.1e-37 128.4 25.9 4.3e-37 127.9 17.9 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EMG47225.1 - 1.7e-13 50.1 0.0 4e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NUFIP1 PF10453.4 EMG47226.1 - 6.9e-19 67.1 9.1 1.5e-18 66.0 6.3 1.6 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) APC_CDC26 PF10471.4 EMG47226.1 - 0.005 17.5 6.3 0.015 16.0 4.3 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 Nucleoplasmin PF03066.10 EMG47226.1 - 0.023 14.2 1.1 0.023 14.2 0.8 2.7 2 2 1 3 3 3 0 Nucleoplasmin WD40 PF00400.27 EMG47227.1 - 1.4e-28 97.6 17.1 3.7e-08 32.9 0.2 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat tRNA-synt_2b PF00587.20 EMG47228.1 - 6.1e-35 120.3 0.0 1.3e-34 119.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EMG47228.1 - 3.4e-23 81.7 7.6 3.4e-23 81.7 5.3 2.0 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain CYSTM PF12734.2 EMG47229.1 - 0.21 11.7 14.0 1 9.4 2.4 2.3 1 1 1 2 2 2 0 Cysteine-rich TM module stress tolerance Ribonuclease_3 PF00636.21 EMG47230.1 - 6.1e-07 29.8 0.5 4.3e-06 27.1 0.0 2.4 2 1 0 2 2 2 1 Ribonuclease III domain Rad10 PF03834.9 EMG47230.1 - 0.036 13.7 1.4 0.085 12.5 0.4 2.1 2 0 0 2 2 2 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Phage_glycop_gL PF11108.3 EMG47230.1 - 1.1 9.2 3.5 1.4 8.8 0.0 2.7 3 1 0 3 3 3 0 Viral glycoprotein L Cytokin_check_N PF10407.4 EMG47231.1 - 2.9e-23 81.2 1.9 2.9e-23 81.2 1.4 2.0 2 0 0 2 2 2 1 Cdc14 phosphatase binding protein N-terminus Cyclin PF08613.6 EMG47232.1 - 4.3e-16 59.6 4.9 8.5e-16 58.7 3.4 1.7 1 1 0 1 1 1 1 Cyclin adh_short_C2 PF13561.1 EMG47233.1 - 7.1e-19 68.5 0.0 8.3e-19 68.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMG47233.1 - 1.2e-12 48.1 0.0 2.1e-12 47.2 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMG47233.1 - 1.1e-08 34.9 0.0 1.9e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EMG47233.1 - 0.023 13.9 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.16 EMG47233.1 - 0.025 14.0 0.1 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Sybindin PF04099.7 EMG47234.1 - 1.1e-17 64.0 1.4 1.4e-17 63.7 1.0 1.1 1 0 0 1 1 1 1 Sybindin-like family ELO PF01151.13 EMG47237.1 - 1.2e-68 231.1 15.9 1.5e-68 230.8 11.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family AATase PF07247.7 EMG47238.1 - 2.6e-104 349.4 12.8 3e-104 349.2 8.9 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase Transferase PF02458.10 EMG47238.1 - 0.00082 17.9 0.0 0.0017 16.8 0.0 1.5 2 0 0 2 2 2 1 Transferase family Condensation PF00668.15 EMG47238.1 - 0.008 15.0 0.1 0.037 12.8 0.1 2.0 1 1 0 1 1 1 1 Condensation domain 2-oxoacid_dh PF00198.18 EMG47238.1 - 0.041 13.1 0.2 4.2 6.5 0.0 2.5 2 0 0 2 2 2 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) HK PF02110.10 EMG47239.1 - 8.4e-76 254.3 2.0 1.5e-75 253.5 1.4 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EMG47239.1 - 1.6e-53 180.5 0.1 2.4e-53 179.9 0.1 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Carb_kinase PF01256.12 EMG47239.1 - 0.00013 21.3 1.0 0.00026 20.3 0.3 1.7 2 0 0 2 2 2 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 EMG47239.1 - 0.00034 19.8 0.1 0.0011 18.2 0.1 1.8 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase WD40 PF00400.27 EMG47240.1 - 6.5e-33 111.4 10.8 1.3e-06 28.0 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat DUF2415 PF10313.4 EMG47240.1 - 0.049 13.3 0.1 7.4 6.3 0.0 3.5 4 1 0 4 4 4 0 Uncharacterised protein domain (DUF2415) Choline_kinase PF01633.15 EMG47241.1 - 4.4e-54 183.2 0.8 7.9e-54 182.4 0.5 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 EMG47241.1 - 1.7e-14 53.0 0.2 3.5e-14 51.9 0.1 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 EMG47241.1 - 8.5e-07 28.9 0.2 1.1e-05 25.2 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF3138 PF11336.3 EMG47242.1 - 0.069 11.3 0.5 0.17 9.9 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) UDP-g_GGTase PF06427.6 EMG47243.1 - 2.2e-48 164.3 1.3 3.8e-48 163.6 0.9 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EMG47243.1 - 1.6e-11 44.0 0.6 3.2e-11 43.0 0.4 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 WLM PF08325.5 EMG47244.1 - 2.6e-46 157.8 0.0 3.3e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 EMG47244.1 - 0.012 15.3 0.1 0.037 13.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF45 Peptidase_M54 PF07998.6 EMG47244.1 - 0.022 14.5 0.5 0.063 13.0 0.2 1.7 1 1 1 2 2 2 0 Peptidase family M54 Tyr_Deacylase PF02580.11 EMG47245.1 - 6.1e-47 159.2 0.0 8.8e-47 158.7 0.0 1.2 1 1 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase EKR PF10371.4 EMG47245.1 - 0.045 13.3 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function MTHFR PF02219.12 EMG47246.1 - 1.6e-117 391.7 0.0 2.3e-117 391.1 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Flocculin_t3 PF13928.1 EMG47248.1 - 1.6e-23 82.5 141.2 4.6e-09 36.2 21.8 15.3 12 1 1 13 13 13 4 Flocculin type 3 repeat DUF1765 PF08578.5 EMG47249.1 - 6.8e-41 139.2 11.5 6.8e-41 139.2 8.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1765) AA_permease_C PF13906.1 EMG47249.1 - 3.9 7.4 6.1 1.8 8.4 1.0 2.4 2 0 0 2 2 2 0 C-terminus of AA_permease ABC2_membrane PF01061.19 EMG47251.1 - 3.8e-87 290.8 63.7 4.5e-47 159.9 15.5 3.4 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 EMG47251.1 - 3.2e-43 145.5 2.8 4.2e-37 125.9 0.1 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 EMG47251.1 - 2.4e-39 134.7 0.0 8.6e-19 68.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 EMG47251.1 - 1.1e-27 95.9 0.0 4.7e-27 93.8 0.0 2.1 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EMG47251.1 - 9.9e-08 31.6 0.2 0.00047 19.6 0.0 2.6 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 EMG47251.1 - 1.8e-07 30.4 0.0 0.00018 20.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EMG47251.1 - 3.6e-05 23.1 0.1 0.022 14.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_19 PF13245.1 EMG47251.1 - 6.1e-05 22.6 0.1 0.45 10.3 0.0 2.5 2 0 0 2 2 2 2 Part of AAA domain AAA_16 PF13191.1 EMG47251.1 - 7.9e-05 22.7 0.3 0.0019 18.2 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain ABC_ATPase PF09818.4 EMG47251.1 - 0.00067 18.3 0.4 0.0073 14.9 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_23 PF13476.1 EMG47251.1 - 0.00097 19.5 5.4 0.25 11.6 0.2 3.1 2 1 0 3 3 3 2 AAA domain AAA_28 PF13521.1 EMG47251.1 - 0.00099 19.1 1.0 0.032 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EMG47251.1 - 0.0013 18.9 0.2 0.57 10.3 0.0 3.4 3 0 0 3 3 2 1 AAA domain cobW PF02492.14 EMG47251.1 - 0.0016 17.8 1.9 0.14 11.5 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EMG47251.1 - 0.0017 19.1 0.2 0.31 11.8 0.0 3.0 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 EMG47251.1 - 0.0021 18.0 0.0 1.1 9.1 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase SMC_N PF02463.14 EMG47251.1 - 0.005 16.0 0.0 0.25 10.5 0.0 2.9 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EMG47251.1 - 0.0098 16.1 0.2 0.51 10.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 EMG47251.1 - 0.014 14.9 0.1 4.4 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain AAA_30 PF13604.1 EMG47251.1 - 0.014 14.9 0.2 3.9 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 EMG47251.1 - 0.015 15.2 0.2 0.35 10.7 0.1 2.8 1 1 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EMG47251.1 - 0.021 14.4 0.4 1.2 8.8 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EMG47251.1 - 0.022 14.4 3.0 3.8 7.1 0.1 3.5 3 0 0 3 3 3 0 NACHT domain Miro PF08477.8 EMG47251.1 - 0.035 14.6 0.3 9 6.8 0.0 3.1 3 0 0 3 3 3 0 Miro-like protein AAA_33 PF13671.1 EMG47251.1 - 0.04 13.7 0.1 3.5 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain fn3 PF00041.16 EMG47251.1 - 0.045 13.8 0.1 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Fibronectin type III domain PduV-EutP PF10662.4 EMG47251.1 - 0.24 10.8 0.7 0.53 9.7 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 EMG47251.1 - 0.26 10.9 0.3 5.4 6.6 0.0 2.7 3 0 0 3 3 3 0 NTPase TPR_16 PF13432.1 EMG47252.1 - 7e-27 93.4 1.1 7.3e-06 26.5 0.0 6.9 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EMG47252.1 - 5.3e-23 79.0 27.8 0.00072 19.2 0.0 12.3 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_11 PF13414.1 EMG47252.1 - 2.3e-21 75.1 22.8 8.9e-05 22.0 0.4 7.6 5 1 3 8 8 8 6 TPR repeat TPR_12 PF13424.1 EMG47252.1 - 3.4e-18 65.3 24.3 0.00071 19.4 0.2 7.5 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 EMG47252.1 - 5.6e-18 65.0 8.7 0.00023 21.4 0.0 7.6 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 EMG47252.1 - 4.3e-16 57.7 24.1 0.0064 16.0 0.0 9.6 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 EMG47252.1 - 9.1e-16 56.9 0.9 0.0095 16.4 0.0 10.1 8 2 3 11 11 10 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMG47252.1 - 5.4e-14 50.8 26.9 0.0042 16.7 0.0 11.0 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_17 PF13431.1 EMG47252.1 - 7.1e-14 50.7 14.1 0.0027 17.7 0.1 10.5 10 0 0 10 10 10 2 Tetratricopeptide repeat Apc3 PF12895.2 EMG47252.1 - 6.1e-12 45.5 21.4 1.6e-07 31.3 1.0 5.0 5 0 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EMG47252.1 - 7.2e-12 44.9 9.5 0.017 15.5 0.0 9.6 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMG47252.1 - 1.4e-09 37.0 6.5 0.13 12.1 0.0 7.6 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 EMG47252.1 - 0.00064 19.5 2.3 37 4.2 0.0 5.6 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 EMG47252.1 - 0.004 17.0 13.9 1.6 8.7 0.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.9 EMG47252.1 - 0.16 12.5 0.0 6.2 7.5 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat AMP-binding PF00501.23 EMG47254.1 - 3.3e-69 233.2 0.0 4.6e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme zf-H2C2_2 PF13465.1 EMG47256.1 - 0.0003 20.9 5.0 0.0043 17.2 0.1 5.1 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMG47256.1 - 0.0023 18.1 3.6 0.034 14.4 0.3 6.3 5 1 0 5 5 5 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EMG47256.1 - 0.013 15.8 9.4 0.029 14.7 0.8 6.7 6 2 1 7 7 7 0 Zinc finger, C2H2 type Med15 PF09606.5 EMG47256.1 - 0.073 11.2 67.0 0.28 9.3 11.8 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal zf-C2H2_jaz PF12171.3 EMG47256.1 - 0.091 12.9 0.1 0.091 12.9 0.0 5.2 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding SprA-related PF12118.3 EMG47256.1 - 3.4 6.9 51.0 4.8 6.4 9.3 2.5 2 0 0 2 2 2 0 SprA-related family F-box PF00646.28 EMG47258.1 - 7.9e-05 22.1 1.2 0.04 13.5 0.1 3.0 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.2 EMG47258.1 - 0.00021 20.9 2.6 0.00026 20.6 0.5 2.1 2 0 0 2 2 2 1 F-box-like EAL PF00563.15 EMG47258.1 - 0.12 11.7 1.9 0.28 10.6 1.3 1.6 1 0 0 1 1 1 0 EAL domain ketoacyl-synt PF00109.21 EMG47259.1 - 2.8e-19 69.5 0.0 5.6e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 EMG47259.1 - 1.8e-17 63.2 0.0 4.1e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EMG47259.1 - 5.2e-11 42.4 1.3 2.8e-10 40.0 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EMG47259.1 - 1.5e-06 28.2 0.0 5e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMG47259.1 - 0.0024 17.5 0.3 0.01 15.5 0.0 2.2 2 0 0 2 2 2 1 KR domain Topoisom_bac PF01131.15 EMG47260.1 - 4.5e-97 325.4 0.0 5.4e-97 325.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EMG47260.1 - 7.4e-20 70.7 0.0 2.4e-19 69.1 0.0 1.9 2 0 0 2 2 2 1 Toprim domain Peptidase_M75 PF09375.5 EMG47260.1 - 0.079 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Imelysin FNIP_C PF14638.1 EMG47260.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus PspA_IM30 PF04012.7 EMG47261.1 - 0.0037 16.6 0.8 0.0095 15.3 0.6 1.8 1 0 0 1 1 1 1 PspA/IM30 family DUF512 PF04459.7 EMG47261.1 - 0.011 14.8 0.2 0.021 13.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF512) Ead_Ea22 PF13935.1 EMG47261.1 - 0.055 13.7 3.9 0.069 13.4 1.7 1.9 2 0 0 2 2 2 0 Ead/Ea22-like protein DivIC PF04977.10 EMG47261.1 - 0.068 12.6 3.4 0.071 12.5 0.9 2.2 2 0 0 2 2 2 0 Septum formation initiator NPV_P10 PF05531.7 EMG47261.1 - 0.087 13.0 2.8 3.7 7.8 0.1 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein APG6 PF04111.7 EMG47261.1 - 0.12 11.4 11.9 0.024 13.7 4.6 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EMG47261.1 - 0.16 11.8 9.5 0.13 12.1 5.1 2.0 2 0 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SecA_SW PF07516.8 EMG47261.1 - 0.42 10.3 12.7 0.18 11.5 4.5 2.5 2 1 0 2 2 2 0 SecA Wing and Scaffold domain TMF_TATA_bd PF12325.3 EMG47261.1 - 1.1 8.9 9.4 0.43 10.3 2.5 2.8 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.14 EMG47261.1 - 1.1 7.0 9.1 0.05 11.4 1.9 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 EMG47261.1 - 1.2 7.4 8.9 2.2 6.6 5.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) IncA PF04156.9 EMG47261.1 - 1.3 8.5 9.0 7.2 6.1 4.7 2.4 1 1 1 2 2 2 0 IncA protein Tropomyosin_1 PF12718.2 EMG47261.1 - 1.4 8.7 14.2 0.21 11.4 4.6 2.9 3 0 0 3 3 3 0 Tropomyosin like DUF2935 PF11155.3 EMG47261.1 - 1.7 8.7 8.9 1.4 9.0 0.7 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) Ax_dynein_light PF10211.4 EMG47261.1 - 3.4 7.4 9.3 1.4 8.6 3.8 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain Seryl_tRNA_N PF02403.17 EMG47261.1 - 5.6 7.0 15.1 0.39 10.7 4.9 3.2 3 2 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain TBPIP PF07106.8 EMG47261.1 - 5.8 6.4 15.0 0.87 9.1 5.5 2.9 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ACCA PF03255.9 EMG47261.1 - 7.6 6.0 11.1 0.58 9.6 1.4 3.2 2 2 1 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit SEN1_N PF12726.2 EMG47262.1 - 6.9e-172 573.2 22.1 9.5e-172 572.7 15.3 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EMG47262.1 - 7.3e-68 228.6 2.6 7.3e-68 228.6 1.8 2.1 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EMG47262.1 - 5.6e-66 221.7 0.5 1.6e-65 220.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMG47262.1 - 6.5e-10 38.6 0.0 1.8e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EMG47262.1 - 1.4e-06 28.0 0.0 0.00059 19.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EMG47262.1 - 6.3e-06 25.8 0.2 0.22 11.0 0.0 3.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 EMG47262.1 - 0.00076 19.0 2.5 0.52 9.7 0.0 4.3 4 1 1 5 5 5 1 DEAD/DEAH box helicase VPS9 PF02204.13 EMG47262.1 - 0.03 14.3 0.4 0.31 11.0 0.0 2.9 3 0 0 3 3 3 0 Vacuolar sorting protein 9 (VPS9) domain Fungal_trans_2 PF11951.3 EMG47263.1 - 1.4e-45 155.5 2.1 1.4e-45 155.5 1.5 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG47263.1 - 1.5e-08 34.3 10.0 2.6e-08 33.6 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COPIIcoated_ERV PF07970.7 EMG47264.1 - 3.5e-33 115.0 0.0 5e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EMG47264.1 - 1e-17 63.8 0.0 2e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) IBR PF01485.16 EMG47265.1 - 8.6e-20 70.3 38.8 9.3e-11 41.4 2.2 4.1 3 1 1 4 4 4 2 IBR domain RWD PF05773.17 EMG47265.1 - 2.2e-18 66.2 0.4 4.9e-18 65.0 0.3 1.6 1 0 0 1 1 1 1 RWD domain zf-C3HC4_2 PF13923.1 EMG47265.1 - 1e-05 25.4 10.0 1e-05 25.4 6.9 4.4 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMG47265.1 - 3.4e-05 23.3 10.4 3.4e-05 23.3 7.2 4.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMG47265.1 - 4.5e-05 23.1 11.0 4.5e-05 23.1 7.6 3.8 3 1 0 3 3 3 2 Ring finger domain zf-RING_UBOX PF13445.1 EMG47265.1 - 2.4 7.9 13.8 0.28 10.9 5.0 2.8 2 0 0 2 2 2 0 RING-type zinc-finger Pex24p PF06398.6 EMG47266.1 - 1.4e-102 343.1 0.6 1.8e-102 342.8 0.4 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Stm1_N PF09598.5 EMG47267.1 - 2.5e-18 66.5 2.8 2.5e-18 66.5 1.9 4.1 3 2 1 4 4 4 1 Stm1 Sec7 PF01369.15 EMG47268.1 - 7.1e-66 221.5 0.4 2.3e-65 219.8 0.3 2.0 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EMG47268.1 - 5.2e-53 178.9 7.2 5.2e-53 178.9 5.0 4.0 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EMG47268.1 - 1.9e-33 113.8 0.9 1.3e-32 111.1 0.4 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) PAT1 PF09770.4 EMG47269.1 - 2.8 6.0 59.9 0.27 9.4 37.9 1.8 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Mito_carr PF00153.22 EMG47270.1 - 3.4e-62 206.1 1.9 2.1e-22 78.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S19 PF00203.16 EMG47271.1 - 4e-31 106.4 0.1 5.4e-31 106.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_60s PF00428.14 EMG47272.1 - 4.2e-27 94.3 13.5 4.9e-27 94.1 9.3 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein FTA4 PF13093.1 EMG47273.1 - 4.7e-40 137.2 15.9 5.9e-40 136.9 11.0 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF221 PF02714.10 EMG47275.1 - 6.5e-101 337.4 20.2 6.5e-101 337.4 14.0 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EMG47275.1 - 3.4e-40 137.1 0.4 3.4e-40 137.1 0.3 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EMG47275.1 - 1.1e-14 54.6 0.0 3e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) YMF19 PF02326.10 EMG47275.1 - 0.014 15.9 0.9 0.014 15.9 0.6 5.3 4 1 2 6 6 6 0 Plant ATP synthase F0 ATG27 PF09451.5 EMG47275.1 - 0.21 10.7 0.0 0.41 9.8 0.0 1.5 1 0 0 1 1 1 0 Autophagy-related protein 27 zf-DNL PF05180.7 EMG47278.1 - 6.8e-28 96.1 0.8 9.9e-28 95.6 0.5 1.3 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.8 EMG47278.1 - 0.00026 20.6 0.3 0.00042 19.9 0.2 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.1 EMG47278.1 - 0.037 13.7 0.1 0.24 11.1 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EMG47278.1 - 0.042 13.4 0.2 0.25 10.9 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-CSL PF05207.8 EMG47278.1 - 0.059 12.8 0.3 0.1 12.1 0.2 1.3 1 0 0 1 1 1 0 CSL zinc finger UPF0167 PF03691.9 EMG47278.1 - 0.092 12.1 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) CpXC PF14353.1 EMG47278.1 - 0.13 12.1 0.9 0.93 9.4 0.8 1.9 1 1 1 2 2 2 0 CpXC protein ATP11 PF06644.6 EMG47279.1 - 9.2e-69 231.9 5.7 7.4e-65 219.0 0.1 2.0 1 1 1 2 2 2 2 ATP11 protein DUF883 PF05957.8 EMG47279.1 - 0.046 14.1 0.7 8 6.9 0.1 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4162 PF13732.1 EMG47279.1 - 0.12 12.9 5.2 0.18 12.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) Pil1 PF13805.1 EMG47279.1 - 0.16 11.0 4.9 0.13 11.3 0.6 2.0 1 1 1 2 2 2 0 Eisosome component PIL1 Kinetocho_Slk19 PF12709.2 EMG47279.1 - 6.5 6.9 10.9 3.7 7.7 5.1 2.4 2 1 1 3 3 3 0 Central kinetochore-associated Mre11_DNA_bind PF04152.9 EMG47280.1 - 2.8e-53 180.3 1.3 2.8e-53 180.3 0.9 1.6 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EMG47280.1 - 1.4e-20 73.5 1.0 2.1e-20 72.9 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Usp PF00582.21 EMG47280.1 - 0.13 12.4 0.2 20 5.3 0.1 3.1 3 0 0 3 3 3 0 Universal stress protein family CemA PF03040.9 EMG47280.1 - 0.37 10.3 1.7 0.79 9.2 1.2 1.6 1 0 0 1 1 1 0 CemA family HGTP_anticodon2 PF12745.2 EMG47281.1 - 4.8e-95 317.8 7.7 4.8e-95 317.8 5.3 2.9 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 EMG47281.1 - 2.2e-70 236.7 0.1 1.7e-39 135.5 0.0 4.4 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EMG47281.1 - 1.6e-39 135.5 0.0 1.1e-17 63.9 0.0 3.7 3 1 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 EMG47281.1 - 2.9e-18 65.8 0.7 1e-17 64.0 0.5 2.0 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 EMG47281.1 - 2e-14 53.3 0.0 1e-13 51.0 0.0 2.2 2 1 0 2 2 2 1 Histidyl-tRNA synthetase Kinase-like PF14531.1 EMG47281.1 - 2.8e-05 23.2 0.0 0.0025 16.8 0.0 3.0 3 0 0 3 3 3 1 Kinase-like UQ_con PF00179.21 EMG47281.1 - 0.0056 16.1 0.3 0.025 14.0 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Choline_kinase PF01633.15 EMG47282.1 - 4.1e-43 147.4 0.0 1.9e-42 145.2 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EMG47282.1 - 0.00019 21.2 0.0 0.0006 19.6 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Sld5 PF05916.6 EMG47283.1 - 6.8e-13 48.8 1.6 1.2e-12 48.0 1.1 1.4 1 1 0 1 1 1 1 GINS complex protein CagZ PF09053.5 EMG47283.1 - 0.013 14.8 0.2 0.028 13.7 0.2 1.5 1 0 0 1 1 1 0 CagZ Mur_ligase_C PF02875.16 EMG47284.1 - 4.1e-05 23.5 0.0 0.0001 22.2 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.7 EMG47284.1 - 0.00068 19.7 1.5 0.0044 17.1 1.0 2.4 1 1 0 1 1 1 1 Mur ligase middle domain ArsC PF03960.10 EMG47284.1 - 0.012 15.7 0.0 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 ArsC family TPR_11 PF13414.1 EMG47285.1 - 1.9e-34 117.1 23.8 2e-14 52.9 1.3 6.9 3 2 5 8 8 8 7 TPR repeat TPR_2 PF07719.12 EMG47285.1 - 5.4e-22 75.8 25.0 0.0044 16.8 0.0 10.9 10 1 1 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.23 EMG47285.1 - 4.9e-21 73.4 16.5 0.00065 19.1 0.0 8.9 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 EMG47285.1 - 7.3e-21 74.3 3.7 1.2e-06 28.9 0.0 5.8 5 1 0 6 6 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 EMG47285.1 - 1.2e-13 50.0 7.8 0.017 15.2 0.2 7.9 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMG47285.1 - 1.8e-13 50.1 17.6 8.8e-05 22.3 0.0 7.0 4 2 2 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EMG47285.1 - 8.4e-12 43.9 21.5 0.05 13.4 0.0 8.9 5 3 3 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 EMG47285.1 - 2.1e-10 40.7 11.9 0.00073 19.8 0.2 5.4 4 2 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMG47285.1 - 3.3e-08 33.4 10.2 0.19 12.4 0.0 7.8 6 3 5 11 11 9 2 Tetratricopeptide repeat Apc3 PF12895.2 EMG47285.1 - 1.1e-05 25.4 17.5 0.049 13.7 2.1 4.8 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.4 EMG47285.1 - 0.00079 19.3 8.4 0.023 14.6 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat SpoIIIAH PF12685.2 EMG47285.1 - 0.0044 16.5 5.0 0.0044 16.5 3.4 2.5 2 0 0 2 2 2 1 SpoIIIAH-like protein TPR_6 PF13174.1 EMG47285.1 - 0.0059 16.9 12.9 0.31 11.5 0.0 6.5 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMG47285.1 - 0.013 15.2 10.4 0.067 13.0 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_15 PF13429.1 EMG47285.1 - 0.023 13.7 2.3 3 6.8 0.0 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EMG47285.1 - 0.024 14.4 2.5 2.8 7.8 0.0 3.7 4 1 1 5 5 4 0 Tetratricopeptide repeat NST1 PF13945.1 EMG47285.1 - 0.43 10.6 10.8 0.98 9.4 7.5 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator ATP_bind_1 PF03029.12 EMG47286.1 - 2.3e-84 282.6 0.6 2.3e-84 282.6 0.4 1.4 2 0 0 2 2 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EMG47286.1 - 2.3e-07 30.4 2.2 5.2e-06 26.0 1.5 2.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EMG47286.1 - 3.3e-05 24.0 0.1 0.00034 20.7 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EMG47286.1 - 5.7e-05 23.9 3.1 0.00017 22.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain ArgK PF03308.11 EMG47286.1 - 0.00018 20.3 0.2 0.49 9.1 0.1 2.4 2 0 0 2 2 2 2 ArgK protein AAA_33 PF13671.1 EMG47286.1 - 0.0002 21.2 0.0 0.0005 19.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EMG47286.1 - 0.00037 20.0 0.5 0.0016 17.9 0.4 1.9 1 1 0 1 1 1 1 AAA-like domain MMR_HSR1 PF01926.18 EMG47286.1 - 0.00056 19.8 0.6 0.0026 17.6 0.2 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EMG47286.1 - 0.0007 19.0 0.0 0.069 12.6 0.0 2.8 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 EMG47286.1 - 0.00086 18.8 0.0 0.016 14.6 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Miro PF08477.8 EMG47286.1 - 0.0014 19.1 0.1 1.7 9.1 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein NACHT PF05729.7 EMG47286.1 - 0.0015 18.2 0.0 0.0031 17.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain FeoB_N PF02421.13 EMG47286.1 - 0.0017 17.6 0.0 0.049 12.9 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B CbiA PF01656.18 EMG47286.1 - 0.0019 17.6 0.5 0.0047 16.3 0.0 1.9 1 1 1 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Arf PF00025.16 EMG47286.1 - 0.003 16.8 0.1 0.35 10.1 0.0 3.1 2 2 0 2 2 2 1 ADP-ribosylation factor family AAA_18 PF13238.1 EMG47286.1 - 0.0035 17.6 6.0 0.033 14.4 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_24 PF13479.1 EMG47286.1 - 0.0036 16.9 0.9 0.0067 16.0 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMG47286.1 - 0.0044 17.0 0.0 0.0097 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain cobW PF02492.14 EMG47286.1 - 0.012 15.1 1.2 0.042 13.2 0.1 2.4 2 1 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.9 EMG47286.1 - 0.022 13.7 0.7 0.16 10.9 0.5 2.1 1 1 0 1 1 1 0 KAP family P-loop domain Septin PF00735.13 EMG47286.1 - 0.023 13.7 1.1 0.069 12.1 0.1 2.2 2 1 0 2 2 2 0 Septin DUF258 PF03193.11 EMG47286.1 - 0.027 13.6 0.1 0.55 9.4 0.0 2.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 ATP-synt_E PF05680.7 EMG47286.1 - 0.041 13.8 1.5 0.12 12.3 1.1 1.7 1 0 0 1 1 1 0 ATP synthase E chain MobB PF03205.9 EMG47286.1 - 0.046 13.4 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EMG47286.1 - 0.048 13.4 0.5 2.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 Viral_helicase1 PF01443.13 EMG47286.1 - 0.056 12.9 0.0 0.22 10.9 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Glyco_tranf_2_3 PF13641.1 EMG47286.1 - 0.086 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 APS_kinase PF01583.15 EMG47286.1 - 0.095 12.3 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase UPF0079 PF02367.12 EMG47286.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Thioredoxin_7 PF13899.1 EMG47286.1 - 0.13 12.3 0.1 0.32 11.0 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin-like Thymidylate_kin PF02223.12 EMG47286.1 - 0.19 11.1 2.6 0.25 10.7 0.0 2.5 3 0 0 3 3 3 0 Thymidylate kinase SRPRB PF09439.5 EMG47286.1 - 0.59 9.3 4.2 1 8.5 0.0 2.7 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit DUF1237 PF06824.6 EMG47287.1 - 2.2e-157 524.0 0.0 2.8e-157 523.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) PAP2 PF01569.16 EMG47288.1 - 1.7e-21 76.2 1.3 1.7e-21 76.2 0.9 1.9 2 0 0 2 2 2 1 PAP2 superfamily Colicin_V PF02674.11 EMG47288.1 - 0.021 14.6 9.5 0.37 10.6 2.2 2.8 1 1 1 2 2 2 0 Colicin V production protein 7TMR-DISM_7TM PF07695.6 EMG47288.1 - 0.18 11.4 12.0 1.3 8.6 3.2 2.6 2 1 0 2 2 2 0 7TM diverse intracellular signalling IspA PF04279.10 EMG47288.1 - 0.2 11.6 5.7 0.39 10.6 0.6 2.5 1 1 1 2 2 2 0 Intracellular septation protein A YibE_F PF07907.6 EMG47288.1 - 0.74 8.9 10.0 0.22 10.6 2.4 2.3 2 0 0 2 2 2 0 YibE/F-like protein AAA PF00004.24 EMG47289.1 - 2e-58 196.2 0.0 6.2e-43 146.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EMG47289.1 - 1e-27 96.0 0.0 2.8e-27 94.5 0.0 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EMG47289.1 - 9.4e-13 48.5 0.2 1.4e-05 25.1 0.0 4.0 3 1 1 4 4 4 2 AAA ATPase domain AAA_14 PF13173.1 EMG47289.1 - 1.4e-09 37.9 2.3 0.0011 18.8 0.1 3.6 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EMG47289.1 - 3.4e-09 37.5 0.0 0.0042 17.8 0.0 3.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMG47289.1 - 1.1e-07 32.0 6.3 0.0031 17.6 1.8 4.2 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EMG47289.1 - 1.1e-06 28.1 2.2 0.38 10.1 0.1 4.1 2 2 2 4 4 4 2 AAA domain IstB_IS21 PF01695.12 EMG47289.1 - 8.8e-06 25.2 0.1 0.11 11.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_2 PF07724.9 EMG47289.1 - 1e-05 25.4 0.0 0.014 15.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) NACHT PF05729.7 EMG47289.1 - 1.5e-05 24.7 3.9 0.024 14.2 0.4 3.9 3 1 0 3 3 3 2 NACHT domain RNA_helicase PF00910.17 EMG47289.1 - 1.5e-05 25.0 2.2 0.037 14.2 0.2 3.2 3 0 0 3 3 2 2 RNA helicase Arch_ATPase PF01637.13 EMG47289.1 - 0.00014 21.6 6.0 0.005 16.5 0.0 4.0 3 1 1 4 4 4 1 Archaeal ATPase AAA_5 PF07728.9 EMG47289.1 - 0.00015 21.5 0.1 0.69 9.6 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 EMG47289.1 - 0.0002 21.6 10.5 0.011 16.0 1.9 3.8 4 1 0 4 4 3 2 ABC transporter Sigma54_activat PF00158.21 EMG47289.1 - 0.00035 20.0 0.1 0.14 11.5 0.0 3.0 2 1 0 2 2 2 1 Sigma-54 interaction domain DUF2075 PF09848.4 EMG47289.1 - 0.00043 19.3 1.2 0.13 11.1 0.0 2.8 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 EMG47289.1 - 0.0005 19.9 0.0 0.23 11.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EMG47289.1 - 0.00074 18.7 0.1 0.82 8.7 0.0 2.9 2 0 0 2 2 2 2 KaiC AAA_18 PF13238.1 EMG47289.1 - 0.00082 19.6 5.5 0.51 10.6 0.0 3.7 4 0 0 4 4 3 2 AAA domain Zeta_toxin PF06414.7 EMG47289.1 - 0.0027 16.8 0.0 0.17 10.9 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin RuvB_N PF05496.7 EMG47289.1 - 0.0027 16.7 0.0 0.016 14.2 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EMG47289.1 - 0.0029 17.3 0.0 1.8 8.3 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain TIP49 PF06068.8 EMG47289.1 - 0.0099 14.6 0.3 0.21 10.2 0.0 2.6 3 0 0 3 3 3 1 TIP49 C-terminus AAA_29 PF13555.1 EMG47289.1 - 0.019 14.5 0.2 0.23 10.9 0.2 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Mg_chelatase PF01078.16 EMG47289.1 - 0.022 13.9 0.1 0.51 9.4 0.1 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 EMG47289.1 - 0.034 13.7 0.0 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EMG47289.1 - 0.056 12.3 0.1 2.8 6.7 0.0 2.7 2 1 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.1 EMG47289.1 - 0.057 12.9 3.4 4.3 6.8 0.2 2.8 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 EMG47289.1 - 0.091 12.7 0.0 3.9 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain GldM_N PF12081.3 EMG47290.1 - 0.14 11.6 1.8 0.2 11.1 1.3 1.2 1 0 0 1 1 1 0 GldM N-terminal domain DUF972 PF06156.8 EMG47290.1 - 0.35 11.2 2.6 1.8 8.9 1.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) IncA PF04156.9 EMG47290.1 - 9.7 5.7 8.0 19 4.7 2.1 2.0 1 1 1 2 2 2 0 IncA protein DUF3767 PF12597.3 EMG47291.1 - 2.2e-45 153.1 0.0 2.9e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DUF3353 PF11833.3 EMG47291.1 - 0.1 12.0 0.6 0.18 11.2 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3353) DUF106 PF01956.11 EMG47292.1 - 7.2e-55 185.0 1.1 8.6e-55 184.8 0.0 1.6 1 1 1 2 2 2 1 Integral membrane protein DUF106 AAA PF00004.24 EMG47293.1 - 1.3e-18 67.4 0.5 9.4e-16 58.2 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EMG47293.1 - 1.3e-15 57.4 0.1 6.4e-15 55.1 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 EMG47293.1 - 4.7e-11 42.5 0.8 1.1e-10 41.3 0.6 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 EMG47293.1 - 2.5e-08 34.1 0.6 8.7e-07 29.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.10 EMG47293.1 - 3.3e-07 29.3 0.1 3.3e-06 26.0 0.0 2.1 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EMG47293.1 - 1.9e-06 28.0 0.4 0.00013 22.0 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.1 EMG47293.1 - 7e-06 25.7 0.0 1.2e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMG47293.1 - 7.1e-06 25.2 0.0 1.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EMG47293.1 - 3.3e-05 23.5 0.0 6.9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EMG47293.1 - 3.5e-05 23.6 0.1 0.00018 21.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EMG47293.1 - 0.00011 21.2 0.0 0.00018 20.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 EMG47293.1 - 0.00032 19.9 0.0 0.0065 15.6 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EMG47293.1 - 0.00056 20.7 0.0 0.0031 18.3 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_23 PF13476.1 EMG47293.1 - 0.001 19.4 0.9 0.0027 18.0 0.6 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EMG47293.1 - 0.0026 17.3 0.5 0.007 15.9 0.4 1.8 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EMG47293.1 - 0.0049 16.3 0.1 0.035 13.5 0.1 2.5 1 1 0 1 1 1 1 AAA-like domain AAA_5 PF07728.9 EMG47293.1 - 0.0052 16.5 0.0 0.021 14.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ResIII PF04851.10 EMG47293.1 - 0.0057 16.5 0.2 0.031 14.1 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EMG47293.1 - 0.0058 16.2 0.0 0.013 15.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EMG47293.1 - 0.0074 15.2 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EMG47293.1 - 0.01 15.2 0.1 0.025 14.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EMG47293.1 - 0.016 14.9 0.7 0.12 12.0 0.0 2.3 2 1 0 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 EMG47293.1 - 0.02 15.2 0.3 2.4 8.4 0.0 2.6 2 1 0 2 2 2 0 ABC transporter TIP49 PF06068.8 EMG47293.1 - 0.02 13.6 0.0 0.11 11.1 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus AAA_18 PF13238.1 EMG47293.1 - 0.021 15.1 0.1 0.093 13.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EMG47293.1 - 0.029 14.3 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EMG47293.1 - 0.036 13.6 0.1 0.48 10.0 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EMG47293.1 - 0.049 13.5 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMG47293.1 - 0.053 13.7 0.0 0.13 12.4 0.0 1.8 1 1 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.13 EMG47293.1 - 0.092 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DSPc PF00782.15 EMG47295.1 - 1.2e-28 99.3 0.8 1.2e-19 70.2 0.0 3.9 3 1 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMG47295.1 - 1.3e-06 27.9 0.3 3.8e-06 26.4 0.1 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase MFS_1 PF07690.11 EMG47296.1 - 1.8e-20 72.9 15.3 1.8e-20 72.9 10.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3453 PF11935.3 EMG47297.1 - 6.1e-55 186.2 3.2 6.1e-55 186.2 2.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) PX PF00787.19 EMG47297.1 - 2.9e-21 75.3 0.1 1.2e-20 73.4 0.0 2.2 1 0 0 1 1 1 1 PX domain BTB_2 PF02214.17 EMG47298.1 - 0.0086 16.2 0.0 0.026 14.7 0.0 1.8 1 1 1 2 2 2 1 BTB/POZ domain Homeobox_KN PF05920.6 EMG47300.1 - 3.2e-17 61.9 0.8 6.8e-17 60.8 0.5 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EMG47300.1 - 4.5e-05 22.9 0.7 9.5e-05 21.9 0.5 1.6 1 0 0 1 1 1 1 Homeobox domain CPSF_A PF03178.10 EMG47302.1 - 1.5e-05 24.2 0.5 0.00052 19.2 0.0 2.9 2 2 2 4 4 4 1 CPSF A subunit region WD40 PF00400.27 EMG47302.1 - 0.013 15.3 0.0 3 7.8 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat Lactonase PF10282.4 EMG47302.1 - 0.025 13.6 0.1 0.1 11.6 0.0 2.0 2 1 1 3 3 3 0 Lactonase, 7-bladed beta-propeller ABC_membrane PF00664.18 EMG47303.1 - 1.6e-82 277.0 29.0 2.1e-49 168.3 4.7 2.6 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMG47303.1 - 4.6e-47 159.7 3.2 1.7e-27 96.3 0.2 2.9 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.14 EMG47303.1 - 6.1e-11 41.9 4.3 5.8e-07 28.9 0.6 3.6 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EMG47303.1 - 5.7e-06 26.2 0.0 0.17 11.8 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 EMG47303.1 - 6.1e-06 26.3 0.2 0.0087 16.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EMG47303.1 - 7.7e-05 22.1 0.3 0.43 10.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EMG47303.1 - 0.00072 18.7 0.3 0.3 10.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EMG47303.1 - 0.00072 20.0 0.2 1.6 9.2 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein UPF0093 PF03653.8 EMG47303.1 - 0.0029 17.5 0.3 0.0029 17.5 0.2 2.2 2 0 0 2 2 1 1 Uncharacterised protein family (UPF0093) AAA_23 PF13476.1 EMG47303.1 - 0.0054 17.0 13.9 0.45 10.8 0.0 3.7 4 1 0 4 4 4 2 AAA domain AAA_10 PF12846.2 EMG47303.1 - 0.0081 15.6 1.9 7.2 5.9 0.0 3.8 3 1 0 4 4 4 1 AAA-like domain Zeta_toxin PF06414.7 EMG47303.1 - 0.0094 15.0 0.2 4.2 6.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Dynamin_N PF00350.18 EMG47303.1 - 0.011 15.5 0.9 1.8 8.3 0.0 3.2 3 0 0 3 3 3 0 Dynamin family AAA_25 PF13481.1 EMG47303.1 - 0.015 14.7 0.0 4.8 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EMG47303.1 - 0.029 13.9 1.1 10 5.6 0.0 2.9 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EMG47303.1 - 0.072 12.5 3.0 4.2 6.8 0.0 3.1 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.12 EMG47303.1 - 0.09 12.5 3.2 0.56 9.9 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_17 PF13207.1 EMG47303.1 - 0.13 13.0 3.8 3.1 8.6 0.6 3.5 3 1 0 3 3 3 0 AAA domain Vma12 PF11712.3 EMG47303.1 - 4.3 7.0 6.6 3.1 7.5 0.0 3.3 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase MFS_1 PF07690.11 EMG47304.1 - 4.2e-20 71.7 22.5 5.9e-20 71.2 15.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4500 PF14937.1 EMG47304.1 - 0.05 13.4 2.3 0.43 10.4 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) DUF485 PF04341.7 EMG47304.1 - 0.43 10.3 9.5 3.1 7.5 1.3 3.7 2 1 1 3 3 3 0 Protein of unknown function, DUF485 Avl9 PF09794.4 EMG47305.1 - 9.1e-128 425.9 7.0 1.3e-127 425.4 4.8 1.2 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 EMG47305.1 - 5.2e-10 39.0 0.7 1.4e-09 37.6 0.5 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 EMG47305.1 - 0.00023 20.8 2.8 0.031 13.9 1.9 2.6 1 1 0 1 1 1 1 Stabilization of polarity axis DENN PF02141.16 EMG47305.1 - 0.0037 17.0 1.8 0.0094 15.6 1.2 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain DUF4366 PF14283.1 EMG47306.1 - 0.011 15.1 0.4 0.014 14.7 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) OAD_gamma PF04277.8 EMG47306.1 - 0.022 15.1 2.9 0.064 13.6 2.0 1.8 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain WWbp PF10349.4 EMG47306.1 - 0.2 12.5 2.6 0.23 12.3 1.8 1.1 1 0 0 1 1 1 0 WW-domain ligand protein LSM PF01423.17 EMG47307.1 - 1.2e-14 53.5 0.0 1.9e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 LSM domain Zip PF02535.17 EMG47307.1 - 0.15 11.0 2.3 0.15 10.9 1.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Gag_spuma PF03276.9 EMG47307.1 - 1.3 7.3 11.8 1.4 7.2 8.2 1.0 1 0 0 1 1 1 0 Spumavirus gag protein PIP5K PF01504.13 EMG47308.1 - 1.3e-63 214.4 3.0 1.7e-63 214.1 2.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase RCR PF12273.3 EMG47309.1 - 5.1e-06 27.0 12.3 5.1e-06 27.0 8.5 2.1 2 1 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red GRP PF07172.6 EMG47309.1 - 0.00019 21.8 0.7 0.93 10.0 0.0 2.3 2 0 0 2 2 2 1 Glycine rich protein family BatA PF07584.6 EMG47309.1 - 0.00081 19.5 1.6 0.0012 19.0 1.1 1.1 1 0 0 1 1 1 1 Aerotolerance regulator N-terminal BatD PF13584.1 EMG47309.1 - 0.0016 17.1 0.0 0.0018 16.9 0.0 1.1 1 0 0 1 1 1 1 Oxygen tolerance WBP-1 PF11669.3 EMG47309.1 - 0.0064 16.5 2.9 0.01 15.8 2.0 1.4 1 1 0 1 1 1 1 WW domain-binding protein 1 ABC2_membrane_4 PF12730.2 EMG47309.1 - 0.014 14.5 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein EphA2_TM PF14575.1 EMG47309.1 - 0.09 13.1 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAM209 PF15206.1 EMG47309.1 - 0.15 11.8 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 FAM209 family DUF2152 PF10222.4 EMG47309.1 - 0.18 9.9 0.0 0.18 9.9 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2152) DUF605 PF04652.11 EMG47310.1 - 0.0083 15.5 26.2 0.014 14.8 18.2 1.4 1 0 0 1 1 1 1 Vta1 like PAT1 PF09770.4 EMG47310.1 - 0.02 13.1 29.0 0.029 12.6 20.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 EMG47310.1 - 8.9 3.8 20.3 14 3.2 14.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) NT-C2 PF10358.4 EMG47311.1 - 2.1e-33 114.8 9.1 9.1e-33 112.7 6.3 1.9 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF4611 PF15387.1 EMG47312.1 - 0.05 13.7 0.8 0.15 12.2 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) IF-2B PF01008.12 EMG47313.1 - 8.7e-46 156.1 0.0 1.1e-45 155.7 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family BChl_A PF02327.12 EMG47313.1 - 0.055 12.0 0.0 0.082 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacteriochlorophyll A protein CENP-W PF15510.1 EMG47313.1 - 0.065 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Centromere kinetochore component W PolC_DP2 PF03833.8 EMG47313.1 - 0.093 10.3 0.0 0.13 9.9 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 UPF0052 PF01933.13 EMG47314.1 - 6.9e-55 186.4 0.0 1.4e-54 185.5 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised protein family UPF0052 WD40 PF00400.27 EMG47315.1 - 8.9e-59 193.4 23.1 9.2e-11 41.2 1.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EMG47315.1 - 1e-06 27.2 10.7 0.0051 15.0 0.1 4.2 1 1 3 4 4 4 4 Nucleoporin Nup120/160 PD40 PF07676.7 EMG47315.1 - 0.064 12.9 0.0 8.5 6.1 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 EMG47315.1 - 0.17 10.5 4.0 31 3.1 0.0 3.9 1 1 0 2 2 2 0 Nup133 N terminal like WD40 PF00400.27 EMG47316.1 - 6.6e-13 47.9 4.7 5.8e-05 22.8 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF3680 PF12441.3 EMG47316.1 - 0.073 12.9 1.7 0.18 11.6 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3680) FKBP_C PF00254.23 EMG47317.1 - 2.2e-31 107.6 0.0 2.7e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Gryzun PF07919.7 EMG47318.1 - 6.8e-36 123.7 12.4 1.2e-35 122.8 8.6 1.3 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 EMG47318.1 - 2.3e-25 89.5 0.0 1.7e-22 80.0 0.0 2.3 1 1 0 1 1 1 1 Foie gras liver health family 1 TBCC PF07986.7 EMG47319.1 - 2.6e-14 52.6 1.0 5.9e-14 51.5 0.7 1.6 1 0 0 1 1 1 1 Tubulin binding cofactor C DUF59 PF01883.14 EMG47319.1 - 2e-07 30.9 0.0 4.5e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF59 bPH_3 PF14470.1 EMG47319.1 - 0.043 14.0 0.7 0.11 12.8 0.5 1.6 1 0 0 1 1 1 0 Bacterial PH domain CENP-B_dimeris PF09026.5 EMG47319.1 - 0.094 12.9 1.7 0.24 11.6 1.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Voldacs PF03517.8 EMG47319.1 - 0.21 11.4 5.0 0.44 10.3 1.2 2.3 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling AMP-binding PF00501.23 EMG47320.1 - 6.1e-64 215.9 0.0 8.2e-62 208.9 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme rve PF00665.21 EMG47321.1 - 4.4e-18 65.5 0.0 1.4e-17 63.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EMG47321.1 - 1.4e-17 63.7 0.0 3.7e-17 62.3 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EMG47321.1 - 0.0023 17.7 2.5 0.0049 16.7 1.8 1.6 1 0 0 1 1 1 1 Zinc knuckle RVT_3 PF13456.1 EMG47321.1 - 0.0037 16.9 0.1 0.4 10.5 0.0 2.7 2 0 0 2 2 2 1 Reverse transcriptase-like rve_3 PF13683.1 EMG47321.1 - 0.12 11.9 0.0 0.43 10.1 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain DUF2404 PF10296.4 EMG47322.1 - 5.6e-07 29.6 0.1 2.9e-05 24.0 0.0 2.7 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) CDC45 PF02724.9 EMG47322.1 - 0.00048 18.3 11.7 0.00048 18.3 8.1 2.1 2 0 0 2 2 2 2 CDC45-like protein SAPS PF04499.10 EMG47322.1 - 0.18 10.4 8.2 0.021 13.4 2.3 1.7 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Adaptin_binding PF10199.4 EMG47322.1 - 1.2 9.4 20.9 0.16 12.2 7.4 2.4 3 0 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 Nop14 PF04147.7 EMG47322.1 - 1.4 6.7 44.7 0.085 10.7 20.9 2.1 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.5 EMG47322.1 - 3.5 6.5 31.3 1.3 8.0 14.3 2.1 2 0 0 2 2 2 0 BUD22 DcpS PF05652.7 EMG47323.1 - 9.6e-31 106.4 0.6 1.3e-30 106.0 0.4 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 EMG47323.1 - 1.5e-07 31.6 0.1 1.4e-06 28.5 0.0 2.1 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DEAD PF00270.24 EMG47324.1 - 6.9e-41 139.5 1.2 1.2e-40 138.8 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EMG47324.1 - 6.2e-20 70.5 0.0 2.5e-19 68.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EMG47324.1 - 2.6e-18 65.6 0.0 6.6e-18 64.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sin_N PF04801.8 EMG47325.1 - 6.1e-18 64.8 0.9 8.3e-18 64.4 0.6 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region CBM_4_9 PF02018.12 EMG47325.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate binding domain LigB PF02900.13 EMG47327.1 - 1.8e-35 122.2 0.0 2.4e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF3785 PF12653.2 EMG47327.1 - 0.066 13.0 0.2 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3785) L51_S25_CI-B8 PF05047.11 EMG47328.1 - 3.3e-10 39.5 0.0 4.4e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain PTS-HPr PF00381.14 EMG47328.1 - 0.052 13.4 0.1 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 PTS HPr component phosphorylation site GFO_IDH_MocA PF01408.17 EMG47329.1 - 3.2e-22 79.3 0.1 5.2e-22 78.6 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EMG47329.1 - 9.8e-15 54.3 0.0 2.6e-14 52.9 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Gp_dh_N PF00044.19 EMG47329.1 - 0.095 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EMG47329.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CAF-1_p150 PF11600.3 EMG47330.1 - 9.9e-07 28.3 35.2 9.9e-07 28.3 24.4 2.5 2 1 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Plus-3 PF03126.13 EMG47331.1 - 2.4e-31 107.9 1.9 3.7e-31 107.3 0.1 2.3 2 0 0 2 2 2 1 Plus-3 domain TPR_15 PF13429.1 EMG47331.1 - 0.00035 19.7 0.6 0.00035 19.7 0.4 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Ribosomal_S28e PF01200.13 EMG47332.1 - 5.2e-34 115.8 2.3 5.6e-34 115.7 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Cyt-b5 PF00173.23 EMG47333.1 - 3.9e-26 90.6 0.5 5.1e-26 90.2 0.4 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ATP_sub_h PF10775.4 EMG47333.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 ATP synthase complex subunit h RRM_1 PF00076.17 EMG47334.1 - 4.8e-18 64.5 0.1 1.2e-17 63.3 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG47334.1 - 7.2e-11 41.9 0.0 1.4e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG47334.1 - 2.1e-09 37.1 0.3 3.7e-09 36.3 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Daxx PF03344.10 EMG47334.1 - 0.00064 18.3 15.1 0.00064 18.3 10.5 1.2 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 EMG47334.1 - 0.053 11.4 24.5 0.084 10.7 17.0 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EMG47334.1 - 0.26 9.2 14.8 0.33 8.9 10.2 1.2 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 EMG47334.1 - 1.1 7.2 10.5 1.5 6.8 7.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Init_tRNA_PT PF04179.7 EMG47334.1 - 1.5 7.5 11.1 0.67 8.7 6.0 1.5 1 1 1 2 2 2 0 Initiator tRNA phosphoribosyl transferase TRAP_alpha PF03896.11 EMG47334.1 - 2 7.3 13.6 3.1 6.6 9.4 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Afi1 PF07792.7 EMG47334.1 - 2.4 8.1 9.5 1.1 9.2 4.9 1.8 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking LMBR1 PF04791.11 EMG47334.1 - 4.6 5.7 7.4 4.1 5.8 5.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Maf PF02545.9 EMG47335.1 - 5.2e-39 133.3 0.0 6.2e-39 133.1 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Syja_N PF02383.13 EMG47336.1 - 1.9e-89 299.6 1.0 3.3e-89 298.8 0.7 1.4 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EMG47336.1 - 1.6e-23 83.9 0.1 2.7e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.20 EMG47339.1 - 1.1e-61 208.3 0.1 7.2e-39 133.4 0.3 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMG47339.1 - 5e-30 104.4 0.1 3.6e-22 78.6 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EMG47339.1 - 2.5e-06 26.6 0.6 1.9e-05 23.7 0.0 2.5 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EMG47339.1 - 0.00013 21.8 0.1 0.0031 17.3 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EMG47339.1 - 0.001 18.1 0.1 0.001 18.1 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EMG47339.1 - 0.0081 15.0 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 PAS_9 PF13426.1 EMG47339.1 - 0.01 16.1 0.0 0.035 14.4 0.0 1.9 1 0 0 1 1 1 0 PAS domain bZIP_2 PF07716.10 EMG47340.1 - 2.9e-12 46.2 9.1 2.9e-12 46.2 6.3 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EMG47340.1 - 1.3e-05 25.0 11.7 1.3e-05 25.0 8.1 2.2 2 0 0 2 2 2 1 bZIP transcription factor XhlA PF10779.4 EMG47340.1 - 0.019 14.8 2.1 0.044 13.6 1.5 1.6 1 0 0 1 1 1 0 Haemolysin XhlA Herpes_BLRF2 PF05812.7 EMG47340.1 - 0.026 14.3 5.2 0.026 14.3 3.6 2.6 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein Ndc1_Nup PF09531.5 EMG47340.1 - 5 5.4 18.3 5.9 5.1 12.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TatD_DNase PF01026.16 EMG47341.1 - 9.7e-41 139.6 0.0 1.5e-39 135.7 0.0 2.0 1 1 0 1 1 1 1 TatD related DNase LRR_8 PF13855.1 EMG47342.1 - 2.3e-07 30.4 21.3 0.0025 17.5 5.0 6.6 5 1 1 6 6 6 4 Leucine rich repeat LRR_4 PF12799.2 EMG47342.1 - 9.7e-06 25.0 24.2 0.0062 16.1 1.8 7.6 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) FNIP PF05725.7 EMG47342.1 - 0.0032 17.3 23.5 2.8 7.9 0.0 7.3 7 1 1 8 8 8 4 FNIP Repeat LRR_6 PF13516.1 EMG47342.1 - 6.8 7.0 13.8 8.2 6.8 0.2 6.6 7 1 1 8 8 8 0 Leucine Rich repeat LRR_7 PF13504.1 EMG47342.1 - 7.2 7.2 16.5 50 4.7 1.3 7.7 9 0 0 9 9 9 0 Leucine rich repeat CBM_21 PF03370.8 EMG47343.1 - 1.8e-27 95.5 2.7 5.9e-27 93.8 1.9 2.0 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 EMG47343.1 - 0.12 12.4 3.4 1.7 8.7 2.3 2.6 1 1 0 1 1 1 0 Carbohydrate binding domain (family 25) Thg1C PF14413.1 EMG47344.1 - 1.9e-50 169.5 6.1 2.6e-50 169.1 4.2 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 EMG47344.1 - 4e-46 155.9 0.6 7e-46 155.1 0.4 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase DUF2924 PF11149.3 EMG47344.1 - 0.023 14.7 0.1 0.047 13.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) tRNA-synt_1c PF00749.16 EMG47345.1 - 4.4e-109 363.9 0.1 1.4e-108 362.2 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 EMG47345.1 - 1.5e-46 157.9 2.1 4.5e-46 156.3 0.1 2.2 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 EMG47345.1 - 1.9e-28 99.3 0.1 8.9e-27 93.8 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 EMG47345.1 - 1.9e-19 70.1 5.6 4.8e-19 68.8 3.9 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 AAA_17 PF13207.1 EMG47346.1 - 1.1e-06 29.4 0.1 3.9e-06 27.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMG47346.1 - 1.7e-06 28.3 0.3 1.7e-05 25.1 0.2 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMG47346.1 - 2.8e-06 26.5 0.0 4.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin PRK PF00485.13 EMG47346.1 - 1.6e-05 24.5 0.0 3.1e-05 23.6 0.0 1.5 2 0 0 2 2 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 EMG47346.1 - 3e-05 23.9 0.0 0.00079 19.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 EMG47346.1 - 0.00097 18.4 0.1 0.0021 17.3 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Arch_ATPase PF01637.13 EMG47346.1 - 0.0024 17.6 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase Thymidylate_kin PF02223.12 EMG47346.1 - 0.0071 15.7 0.1 0.018 14.4 0.0 1.7 2 0 0 2 2 2 1 Thymidylate kinase AAA_16 PF13191.1 EMG47346.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ArgK PF03308.11 EMG47346.1 - 0.014 14.1 0.0 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 ArgK protein T2SE PF00437.15 EMG47346.1 - 0.017 14.0 0.0 0.058 12.2 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein SRP54 PF00448.17 EMG47346.1 - 0.017 14.5 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain UPF0079 PF02367.12 EMG47346.1 - 0.017 14.7 0.0 0.074 12.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 EMG47346.1 - 0.02 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 NTPase KAP_NTPase PF07693.9 EMG47346.1 - 0.034 13.1 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_22 PF13401.1 EMG47346.1 - 0.047 13.8 0.0 0.089 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EMG47346.1 - 0.051 13.4 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit APS_kinase PF01583.15 EMG47346.1 - 0.053 13.1 0.0 0.11 12.1 0.0 1.5 2 0 0 2 2 1 0 Adenylylsulphate kinase cobW PF02492.14 EMG47346.1 - 0.067 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DnaB_C PF03796.10 EMG47346.1 - 0.072 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_19 PF13245.1 EMG47346.1 - 0.098 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Viral_helicase1 PF01443.13 EMG47346.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.7 EMG47346.1 - 0.13 11.8 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RNA_pol_Rpb2_6 PF00562.23 EMG47347.1 - 7.9e-113 377.0 0.0 1.2e-112 376.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EMG47347.1 - 2.9e-40 137.3 0.2 4.4e-40 136.7 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EMG47347.1 - 8e-31 106.9 0.0 1.9e-30 105.6 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 EMG47347.1 - 1.5e-24 85.5 0.0 3.6e-24 84.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 EMG47347.1 - 1.5e-23 82.5 0.0 3.1e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 EMG47347.1 - 3.1e-15 56.1 0.0 1e-14 54.5 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EMG47347.1 - 0.00053 19.8 0.1 0.0015 18.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 tRNA-synt_1c PF00749.16 EMG47348.1 - 1.4e-111 372.1 0.0 1.9e-111 371.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EMG47348.1 - 2e-40 138.3 0.8 5.7e-40 136.8 0.5 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EMG47348.1 - 2.8e-08 34.1 0.1 7.9e-08 32.6 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMG47348.1 - 3.5e-06 26.9 0.3 9.2e-06 25.5 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMG47348.1 - 0.00017 21.3 0.0 0.00038 20.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RRM_4 PF10598.4 EMG47348.1 - 0.043 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif of the spliceosomal PrP8 DUF155 PF02582.9 EMG47349.1 - 3.2e-62 209.5 0.6 7.8e-62 208.2 0.4 1.7 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 PIN_4 PF13638.1 EMG47350.1 - 2.9e-29 101.8 0.2 1.2e-28 99.8 0.0 1.9 2 0 0 2 2 2 1 PIN domain XLF PF09302.6 EMG47351.1 - 0.00018 21.3 2.9 0.00035 20.3 0.4 2.4 2 1 0 2 2 2 1 XLF (XRCC4-like factor) SUR7 PF06687.7 EMG47352.1 - 3e-36 124.9 10.9 3.8e-36 124.6 7.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EMG47352.1 - 0.0058 16.3 8.8 0.0058 16.3 6.1 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4064 PF13273.1 EMG47352.1 - 0.028 14.5 4.4 1.3 9.1 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF4491 PF14898.1 EMG47352.1 - 3.2 7.9 11.5 0.72 10.0 1.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4491) DUF4451 PF14616.1 EMG47353.1 - 1.2e-29 102.6 1.9 3.6e-29 101.0 1.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4451) AA_permease PF00324.16 EMG47354.1 - 3.4e-90 302.7 40.0 4.3e-90 302.3 27.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG47354.1 - 1.2e-23 83.3 42.3 1.4e-23 83.1 28.9 1.3 1 1 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 EMG47355.1 - 4.9e-49 166.8 0.1 6.2e-49 166.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG47355.1 - 2.9e-27 95.3 0.0 6e-27 94.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG47355.1 - 6.7e-10 38.3 0.0 9.2e-09 34.6 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EMG47355.1 - 0.00013 21.0 0.0 0.00025 20.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EMG47355.1 - 0.0012 18.1 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EMG47355.1 - 0.0072 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3596 PF12167.3 EMG47355.1 - 0.029 13.9 0.1 0.029 13.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3596) RRM_1 PF00076.17 EMG47356.1 - 1.8e-12 46.6 0.0 2.2e-10 40.0 0.0 3.2 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG47356.1 - 4.1e-07 29.8 0.0 2.2e-06 27.5 0.0 2.3 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) 4HBT_3 PF13622.1 EMG47356.1 - 0.3 10.7 18.1 0.023 14.4 5.6 2.5 2 0 0 2 2 2 0 Thioesterase-like superfamily PHD PF00628.24 EMG47357.1 - 3.3e-15 55.5 25.6 6.1e-08 32.2 9.6 2.5 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.17 EMG47357.1 - 0.005 16.5 0.6 0.005 16.5 0.4 2.8 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EMG47357.1 - 0.018 14.7 2.5 0.018 14.7 1.7 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 EMG47357.1 - 0.049 12.9 11.6 1.6 8.1 0.2 2.9 2 0 0 2 2 2 0 PHD-finger zf-HC5HC2H PF13771.1 EMG47357.1 - 0.36 10.9 13.7 0.083 13.0 4.0 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain L51_S25_CI-B8 PF05047.11 EMG47358.1 - 4.9e-07 29.3 0.1 1.1e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ArgJ PF01960.13 EMG47360.1 - 3.3e-150 499.8 2.3 3.8e-150 499.6 1.6 1.0 1 0 0 1 1 1 1 ArgJ family Orexin PF02072.10 EMG47360.1 - 0.053 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Prepro-orexin PCRF PF03462.13 EMG47360.1 - 0.086 12.5 0.1 0.46 10.1 0.0 2.1 2 1 0 2 2 2 0 PCRF domain RNA_pol PF00940.14 EMG47361.1 - 3e-123 411.3 1.9 3e-123 411.3 1.3 2.5 3 0 0 3 3 3 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EMG47361.1 - 4.5e-15 55.7 0.0 1e-14 54.5 0.0 1.7 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal DUF1762 PF08574.5 EMG47362.1 - 2.6e-23 82.2 13.6 2.6e-23 82.2 9.4 3.5 3 1 1 4 4 4 1 Protein of unknown function (DUF1762) TRAPP PF04051.11 EMG47363.1 - 1.8e-22 79.4 0.0 2.6e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ribosomal_S16 PF00886.14 EMG47365.1 - 2.1e-19 68.9 0.0 2.9e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 Lactamase_B_4 PF13691.1 EMG47365.1 - 0.071 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 tRNase Z endonuclease NUC173 PF08161.7 EMG47366.1 - 9.4e-75 250.3 1.4 1.2e-69 233.6 0.0 3.5 3 0 0 3 3 3 2 NUC173 domain BTB PF00651.26 EMG47367.1 - 8.2e-21 74.0 0.4 1.4e-12 47.6 0.0 3.0 2 1 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 EMG47367.1 - 4.2e-08 33.4 0.0 4.7e-07 30.1 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMG47367.1 - 9.2e-08 32.3 0.0 8.5e-07 29.2 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMG47367.1 - 1.4e-07 30.9 0.2 0.00017 21.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EMG47367.1 - 3e-07 30.4 0.0 9.8e-06 25.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMG47367.1 - 5.5e-05 23.0 0.2 1 9.7 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat ACBP PF00887.14 EMG47368.1 - 1.8e-27 94.8 0.5 4.3e-27 93.5 0.3 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein Epimerase PF01370.16 EMG47368.1 - 2.7e-11 43.3 1.0 2.4e-10 40.2 0.7 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMG47368.1 - 9.3e-10 37.6 0.0 1.5e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMG47368.1 - 8.6e-07 28.1 0.5 4.1e-05 22.6 0.4 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EMG47368.1 - 2.5e-06 27.6 0.5 5.4e-06 26.5 0.3 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMG47368.1 - 4.1e-06 26.8 0.4 1.5e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 EMG47368.1 - 7.8e-05 22.0 0.1 0.00074 18.8 0.1 2.3 2 1 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 EMG47368.1 - 0.095 11.5 0.1 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein WW PF00397.21 EMG47369.1 - 0.27 11.1 1.3 0.44 10.4 0.0 2.1 2 0 0 2 2 2 0 WW domain Peptidase_M24 PF00557.19 EMG47370.1 - 1.2e-24 87.0 0.0 1.6e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Phosphorylase PF00343.15 EMG47371.1 - 0 1027.1 0.8 0 1026.9 0.6 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase PAS_10 PF13596.1 EMG47371.1 - 0.019 15.2 0.5 3.3 8.0 0.0 3.0 3 0 0 3 3 3 0 PAS domain Peptidase_S10 PF00450.17 EMG47372.1 - 2.9e-91 306.6 1.2 3.6e-91 306.4 0.2 1.6 2 0 0 2 2 2 1 Serine carboxypeptidase DUF605 PF04652.11 EMG47372.1 - 0.36 10.1 6.8 0.57 9.5 4.7 1.2 1 0 0 1 1 1 0 Vta1 like Ribosomal_S13 PF00416.17 EMG47373.1 - 4.4e-40 136.4 1.0 1e-39 135.2 0.7 1.6 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Ribosomal_L4 PF00573.17 EMG47373.1 - 1e-33 116.3 0.0 2.4e-33 115.1 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family FbpA PF05833.6 EMG47373.1 - 0.0058 15.2 0.5 0.0089 14.6 0.0 1.5 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Homeobox PF00046.24 EMG47374.1 - 1.8e-15 56.2 4.8 3.3e-15 55.4 3.3 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMG47374.1 - 0.043 13.5 1.9 0.092 12.4 0.2 2.5 3 0 0 3 3 3 0 Homeobox KN domain RNase_H2-Ydr279 PF09468.5 EMG47375.1 - 0.0025 17.0 1.6 0.0025 17.0 1.1 2.3 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) Metallophos PF00149.23 EMG47375.1 - 0.0054 16.1 6.2 0.023 14.0 4.3 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase BLVR PF06375.6 EMG47375.1 - 5.8 6.7 19.7 5.6 6.7 6.8 2.4 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Ribosomal_L10 PF00466.15 EMG47376.1 - 1e-27 95.9 0.1 2e-27 95.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EMG47376.1 - 9.3e-08 32.3 3.4 2e-07 31.2 0.8 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein S19 PF06756.6 EMG47376.1 - 0.05 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Chorion protein S19 C-terminal Enkurin PF13864.1 EMG47377.1 - 0.039 14.1 2.6 0.06 13.5 0.1 2.0 2 0 0 2 2 2 0 Calmodulin-binding Sigma70_r4_2 PF08281.7 EMG47377.1 - 0.068 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_29 PF13551.1 EMG47377.1 - 0.093 12.8 0.1 0.32 11.1 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn helix DUF1098 PF06497.6 EMG47377.1 - 0.26 11.3 2.0 15 5.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) PWWP PF00855.12 EMG47379.1 - 8.9e-21 73.8 1.2 1.9e-20 72.8 0.0 2.2 2 0 0 2 2 2 1 PWWP domain SRF-TF PF00319.13 EMG47380.1 - 1.7e-23 81.5 0.2 2.4e-23 81.0 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Suf PF05843.9 EMG47380.1 - 0.49 10.0 4.9 0.58 9.8 3.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 EMG47380.1 - 2.8 6.0 25.5 3.5 5.7 17.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Synaphin PF05835.7 EMG47380.1 - 5.7 7.0 8.8 0.65 10.1 0.3 2.5 2 1 0 2 2 2 0 Synaphin protein PSP1 PF04468.7 EMG47381.1 - 7.8e-32 109.1 0.0 7.8e-32 109.1 0.0 2.0 2 0 0 2 2 2 1 PSP1 C-terminal conserved region Copper-fist PF00649.13 EMG47382.1 - 2.3e-21 74.6 1.7 6.6e-21 73.2 1.2 1.8 1 0 0 1 1 1 1 Copper fist DNA binding domain DUF4183 PF13799.1 EMG47383.1 - 0.0049 16.6 0.0 0.037 13.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4183) TPR_11 PF13414.1 EMG47385.1 - 7.6e-36 121.5 32.5 4.5e-07 29.4 1.1 10.8 9 3 2 11 11 11 7 TPR repeat TPR_2 PF07719.12 EMG47385.1 - 9.9e-30 100.0 34.3 0.02 14.7 0.0 15.1 15 2 1 16 16 16 8 Tetratricopeptide repeat TPR_1 PF00515.23 EMG47385.1 - 8e-29 98.0 36.8 0.0012 18.3 0.3 14.5 15 0 0 15 15 15 7 Tetratricopeptide repeat TPR_16 PF13432.1 EMG47385.1 - 1.3e-27 95.7 0.4 0.0014 19.2 0.0 10.3 8 3 3 11 11 11 8 Tetratricopeptide repeat TPR_12 PF13424.1 EMG47385.1 - 2.9e-23 81.6 27.7 3.1e-08 33.4 0.0 10.9 9 3 4 14 14 14 4 Tetratricopeptide repeat TPR_8 PF13181.1 EMG47385.1 - 1.2e-21 74.7 43.4 4.5e-06 26.0 0.5 12.6 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_19 PF14559.1 EMG47385.1 - 1.5e-19 70.0 18.4 8.4e-07 29.2 0.0 11.1 9 3 2 12 12 11 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMG47385.1 - 4.5e-16 57.8 8.2 0.22 12.2 0.0 12.3 12 3 3 15 15 13 2 Tetratricopeptide repeat Apc3 PF12895.2 EMG47385.1 - 1.6e-10 40.9 21.7 0.00067 19.7 0.1 8.8 6 4 4 10 10 10 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EMG47385.1 - 2e-10 39.6 15.5 0.027 14.2 0.0 11.9 14 0 0 14 14 13 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMG47385.1 - 4.3e-09 35.8 23.8 0.44 10.8 0.0 12.8 14 0 0 14 14 14 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMG47385.1 - 8.5e-08 32.1 27.9 8.5 7.0 0.1 12.5 14 0 0 14 14 13 1 Tetratricopeptide repeat TPR_10 PF13374.1 EMG47385.1 - 1.5e-05 24.7 8.4 0.6 10.1 0.0 8.4 10 0 0 10 10 10 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 EMG47385.1 - 0.086 12.0 7.8 2 7.7 0.0 5.1 6 0 0 6 6 6 0 SHNi-TPR NmrA PF05368.8 EMG47387.1 - 5.1e-08 32.4 0.0 7.4e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.15 EMG47387.1 - 0.00019 21.3 0.0 0.00053 19.8 0.0 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 EMG47387.1 - 0.009 16.0 0.0 0.02 14.9 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 EMG47387.1 - 0.063 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NmrA PF05368.8 EMG47388.1 - 2.6e-09 36.6 0.3 4.2e-09 35.9 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMG47388.1 - 0.00049 20.1 0.0 0.0014 18.6 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding DapB_N PF01113.15 EMG47388.1 - 0.021 14.7 0.0 0.067 13.1 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CFEM PF05730.6 EMG47389.1 - 1.3e-09 37.7 13.6 3.6e-09 36.3 9.4 1.8 1 0 0 1 1 1 1 CFEM domain DUF2201_N PF13203.1 EMG47389.1 - 0.091 11.9 6.0 0.096 11.8 4.1 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF605 PF04652.11 EMG47389.1 - 0.39 10.0 19.3 0.45 9.8 13.4 1.0 1 0 0 1 1 1 0 Vta1 like TP53IP5 PF15331.1 EMG47389.1 - 0.41 10.5 6.6 0.52 10.1 4.6 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 CDC45 PF02724.9 EMG47389.1 - 1.3 6.9 11.5 1.5 6.7 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 EMG47389.1 - 2.1 5.9 15.5 2.3 5.7 10.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DHHW PF14286.1 EMG47389.1 - 2.3 7.4 11.2 3.3 6.9 7.8 1.3 1 0 0 1 1 1 0 DHHW protein Ndc1_Nup PF09531.5 EMG47389.1 - 3.5 5.9 13.7 3.8 5.8 9.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Raftlin PF15250.1 EMG47389.1 - 3.6 6.0 9.7 4 5.8 6.7 1.2 1 0 0 1 1 1 0 Raftlin BUD22 PF09073.5 EMG47389.1 - 6 5.8 21.7 7 5.5 15.1 1.1 1 0 0 1 1 1 0 BUD22 DUF1510 PF07423.6 EMG47389.1 - 6.2 6.1 16.4 8.1 5.7 11.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1675 PF07897.6 EMG47389.1 - 7.6 6.3 24.4 9.9 5.9 16.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Hex_IIIa PF02455.11 EMG47389.1 - 8.1 4.9 10.1 10 4.6 7.0 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Utp14 PF04615.8 EMG47389.1 - 8.4 4.4 14.0 9.7 4.2 9.7 1.0 1 0 0 1 1 1 0 Utp14 protein Amidohydro_1 PF01979.15 EMG47390.1 - 2.3e-36 126.1 0.0 3e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EMG47390.1 - 0.00025 20.3 0.1 0.097 11.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.17 EMG47390.1 - 0.00078 18.4 0.1 0.0012 17.7 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_5 PF13594.1 EMG47390.1 - 0.003 17.3 0.1 0.014 15.2 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EMG47390.1 - 0.022 14.8 0.0 5.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Amidohydrolase MFS_1 PF07690.11 EMG47391.1 - 3.8e-22 78.4 22.6 5.6e-18 64.7 9.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG47391.1 - 6.8e-21 74.3 16.6 9.6e-21 73.8 11.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Methyltransf_PK PF05891.7 EMG47392.1 - 1.1e-79 266.7 0.0 1.3e-79 266.5 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Mid2 PF04478.7 EMG47393.1 - 1e-10 41.2 2.3 1e-10 41.2 1.6 2.6 1 1 2 3 3 3 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 EMG47393.1 - 0.0012 18.1 1.9 0.0012 18.1 1.3 2.8 3 0 0 3 3 3 1 Transmembrane alpha-helix domain DUF1191 PF06697.7 EMG47393.1 - 0.017 13.9 0.2 0.025 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF4541 PF15074.1 EMG47394.1 - 0.22 12.0 8.1 0.16 12.5 0.8 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4541) Peptidase_S46 PF10459.4 EMG47394.1 - 1.7 7.0 29.8 2.3 6.5 20.6 1.2 1 0 0 1 1 1 0 Peptidase S46 DUF2285 PF10074.4 EMG47394.1 - 7.8 6.8 8.3 1.2 9.5 2.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2285) RRM_1 PF00076.17 EMG47395.1 - 1.4e-54 181.5 2.0 1.1e-19 69.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG47395.1 - 4.9e-39 132.1 0.6 6e-12 45.3 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG47395.1 - 3.4e-14 52.4 0.1 2.8e-05 23.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1388 PF07142.7 EMG47395.1 - 9.1e-05 22.0 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 Repeat of unknown function (DUF1388) DUF1325 PF07039.6 EMG47396.1 - 2.1e-29 101.7 0.0 3.4e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain Spc7 PF08317.6 EMG47396.1 - 0.011 14.4 6.9 0.014 14.0 4.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein PRTP PF01366.13 EMG47396.1 - 0.046 11.7 3.6 0.07 11.1 2.5 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Atg14 PF10186.4 EMG47396.1 - 0.98 8.3 8.9 1.4 7.7 6.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PLDc_2 PF13091.1 EMG47397.1 - 8.4e-16 57.8 0.0 8.2e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EMG47397.1 - 1.8e-07 30.7 0.0 0.0019 17.9 0.0 2.8 2 1 0 2 2 2 2 Phospholipase D Active site motif IBN_N PF03810.14 EMG47398.1 - 7.3e-07 29.0 0.4 7.3e-07 29.0 0.3 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EMG47398.1 - 0.0088 15.9 0.0 0.0088 15.9 0.0 4.5 5 1 0 5 5 5 1 Exportin 1-like protein HEAT_2 PF13646.1 EMG47398.1 - 0.12 12.6 1.5 3.7 7.8 0.3 3.7 4 1 0 4 4 4 0 HEAT repeats DUF2015 PF09435.5 EMG47399.1 - 5.2e-39 132.9 0.3 6.1e-39 132.7 0.2 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Epimerase PF01370.16 EMG47400.1 - 1.6e-14 53.9 0.0 2.8e-14 53.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMG47400.1 - 1.2e-11 45.0 2.0 3.6e-10 40.1 1.4 2.4 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMG47400.1 - 6.5e-07 28.5 0.0 0.0021 17.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.8 EMG47400.1 - 3.5e-06 26.4 0.1 0.00013 21.2 0.0 2.4 2 1 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 EMG47400.1 - 6.7e-06 25.0 0.0 9.3e-06 24.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EMG47400.1 - 0.0051 16.7 0.0 0.011 15.6 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EMG47400.1 - 0.027 13.3 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EMG47400.1 - 0.074 11.9 0.0 0.19 10.5 0.0 1.6 1 0 0 1 1 1 0 RmlD substrate binding domain ELFV_dehydrog PF00208.16 EMG47400.1 - 0.15 11.6 0.0 1 8.9 0.0 2.1 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF2036 PF09724.4 EMG47401.1 - 3.4e-69 233.4 0.9 4.6e-69 233.0 0.6 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) RR_TM4-6 PF06459.7 EMG47402.1 - 0.38 10.6 7.4 0.078 12.8 2.6 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.3 EMG47402.1 - 2.7 6.4 8.5 1 7.8 3.8 1.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Sugar_tr PF00083.19 EMG47403.1 - 6.2e-125 417.3 21.1 7e-125 417.1 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG47403.1 - 5.2e-27 94.4 17.8 5.2e-27 94.4 12.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2456 PF10445.4 EMG47403.1 - 0.0056 16.5 0.4 0.0056 16.5 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) DUF2530 PF10745.4 EMG47403.1 - 0.7 9.9 4.8 2.1 8.4 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Mito_carr PF00153.22 EMG47404.1 - 4.7e-55 183.2 1.1 2.1e-18 65.8 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Aminotran_5 PF00266.14 EMG47405.1 - 2.1e-96 322.9 0.0 2.5e-96 322.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EMG47405.1 - 1.8e-08 33.9 0.0 2.4e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.14 EMG47405.1 - 0.00014 20.4 0.1 0.00022 19.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.12 EMG47405.1 - 0.00064 18.8 0.0 0.0019 17.2 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Iso_dh PF00180.15 EMG47406.1 - 1.2e-128 428.9 0.0 1.4e-128 428.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF3507 PF12015.3 EMG47407.1 - 9.9e-61 204.4 0.9 2e-60 203.4 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) NAD_binding_10 PF13460.1 EMG47408.1 - 2.8e-14 53.5 0.0 1.3e-13 51.4 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMG47408.1 - 5.2e-07 28.8 0.0 4.5e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EMG47408.1 - 2.8e-06 26.9 0.0 3.5e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMG47408.1 - 0.0005 18.8 0.0 0.0009 18.0 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EMG47408.1 - 0.01 15.7 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 EMG47408.1 - 0.061 12.2 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Methyltransf_3 PF01596.12 EMG47408.1 - 0.12 11.3 0.0 0.44 9.5 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase HPP PF04982.8 EMG47409.1 - 4.4e-38 129.8 4.2 6.8e-38 129.1 2.9 1.3 1 0 0 1 1 1 1 HPP family E1-E2_ATPase PF00122.15 EMG47410.1 - 3.2e-78 261.9 3.0 3.2e-78 261.9 2.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMG47410.1 - 1.5e-43 148.4 2.1 1.5e-43 148.4 1.5 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMG47410.1 - 8e-34 117.9 0.0 5.7e-33 115.1 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMG47410.1 - 4.9e-16 58.4 0.0 1.7e-15 56.7 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EMG47410.1 - 3.7e-15 55.1 0.1 1e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EMG47410.1 - 1.6e-14 54.5 0.0 3.4e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMG47410.1 - 2.4e-09 37.1 2.5 4.7e-06 26.3 1.0 2.6 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.7 EMG47410.1 - 0.048 13.2 0.0 0.17 11.4 0.0 1.9 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Sua5_yciO_yrdC PF01300.13 EMG47411.1 - 5.6e-51 172.3 0.0 8.1e-51 171.8 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EMG47411.1 - 6.5e-33 113.4 0.0 1e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Telomere_reg-2 PF10193.4 EMG47413.1 - 4.8e-33 113.8 0.2 1.7e-32 112.0 0.1 2.0 1 0 0 1 1 1 1 Telomere length regulation protein Thi4 PF01946.12 EMG47414.1 - 0.048 12.7 0.0 0.39 9.7 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Aa_trans PF01490.13 EMG47415.1 - 3.4e-64 216.8 28.2 4.5e-64 216.4 19.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FUSC PF04632.7 EMG47415.1 - 0.77 8.1 5.1 1.3 7.3 3.5 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family MerC PF03203.9 EMG47415.1 - 1.8 8.9 21.6 0.2 12.0 3.0 3.1 3 0 0 3 3 3 0 MerC mercury resistance protein FMN_bind_2 PF04299.7 EMG47416.1 - 9.5e-56 187.9 0.6 1.2e-55 187.6 0.4 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain RRM_1 PF00076.17 EMG47417.1 - 2.9e-17 62.0 0.0 5e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG47417.1 - 1.5e-13 50.5 0.0 2.3e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG47417.1 - 2.1e-09 37.1 0.0 3.5e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRP PF07172.6 EMG47417.1 - 0.021 15.3 11.5 0.039 14.4 8.0 1.4 1 0 0 1 1 1 0 Glycine rich protein family Fasciclin PF02469.17 EMG47418.1 - 8.1e-17 61.4 5.1 9.3e-06 25.6 0.0 5.3 5 1 1 6 6 6 3 Fasciclin domain BRCA-2_helical PF09169.5 EMG47418.1 - 0.069 12.7 0.2 0.18 11.3 0.1 1.7 1 0 0 1 1 1 0 BRCA2, helical NAD_binding_6 PF08030.7 EMG47419.1 - 7.3e-19 68.2 0.4 1.2e-18 67.5 0.3 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMG47419.1 - 6.8e-17 61.2 0.0 1.8e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EMG47419.1 - 2.3e-16 59.9 13.1 3.2e-16 59.5 4.0 2.6 3 0 0 3 3 3 2 Ferric reductase like transmembrane component Ureide_permease PF07168.6 EMG47419.1 - 0.0023 16.6 0.6 0.0043 15.7 0.4 1.3 1 0 0 1 1 1 1 Ureide permease FAD_binding_6 PF00970.19 EMG47419.1 - 0.084 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain RhoGAP PF00620.22 EMG47420.1 - 9.4e-39 132.4 1.8 5.1e-23 81.3 0.0 2.7 3 0 0 3 3 3 2 RhoGAP domain DUF3437 PF11919.3 EMG47420.1 - 0.057 13.1 0.1 6.1 6.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Peptidase_M28 PF04389.12 EMG47421.1 - 8.2e-18 64.7 0.1 1.6e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 EMG47421.1 - 9.3e-14 51.0 0.0 1.7e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 EMG47421.1 - 1e-11 44.3 0.1 3.8e-11 42.5 0.1 2.0 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 EMG47421.1 - 6.4e-05 22.3 0.0 0.00017 20.8 0.0 1.7 1 0 0 1 1 1 1 Nicastrin Peptidase_M20 PF01546.23 EMG47421.1 - 0.0022 17.5 0.0 0.0048 16.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Spore_III_AB PF09548.5 EMG47422.1 - 1.6 8.4 5.4 0.18 11.5 0.6 1.7 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Hid1 PF12722.2 EMG47423.1 - 0.58 7.7 11.1 0.9 7.1 7.7 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Alb1 PF09135.6 EMG47424.1 - 1.7e-15 57.6 6.7 1.7e-15 57.6 4.6 1.4 2 0 0 2 2 2 1 Alb1 Med3 PF11593.3 EMG47424.1 - 8.9 5.4 10.2 9.8 5.3 7.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribul_P_3_epim PF00834.14 EMG47425.1 - 2.7e-70 235.5 0.0 3.2e-70 235.3 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Amidohydro_2 PF04909.9 EMG47425.1 - 0.013 15.0 0.0 0.034 13.7 0.0 1.6 1 1 0 1 1 1 0 Amidohydrolase Radical_SAM PF04055.16 EMG47425.1 - 0.014 15.5 0.0 0.34 11.0 0.0 2.2 1 1 1 2 2 2 0 Radical SAM superfamily PG_binding_3 PF09374.5 EMG47425.1 - 0.11 12.5 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Predicted Peptidoglycan domain QRPTase_C PF01729.14 EMG47425.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain A_deamin PF02137.13 EMG47426.1 - 1.1e-56 192.6 0.0 1.9e-56 191.8 0.0 1.4 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Fis1_TPR_C PF14853.1 EMG47426.1 - 4.6e-24 84.0 0.1 9.3e-24 83.0 0.1 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EMG47426.1 - 6.5e-15 54.1 0.0 1.6e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EMG47426.1 - 0.0026 17.5 0.0 0.0054 16.5 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF4168 PF13767.1 EMG47426.1 - 0.03 14.9 0.0 0.065 13.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) Sod_Fe_C PF02777.13 EMG47427.1 - 7.3e-33 112.5 0.8 1.3e-32 111.8 0.6 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EMG47427.1 - 6.7e-27 93.5 0.9 1.3e-26 92.6 0.6 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain FAD_binding_8 PF08022.7 EMG47428.1 - 4.9e-13 48.8 0.1 1.5e-12 47.3 0.0 1.9 2 1 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 EMG47428.1 - 2.8e-10 40.3 0.0 4.2e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMG47428.1 - 2e-09 37.5 8.8 2e-09 37.5 6.1 1.8 1 1 1 2 2 2 2 Ferric reductase like transmembrane component BAR PF03114.13 EMG47429.1 - 1.3e-51 175.3 3.4 1.9e-51 174.7 2.4 1.3 1 0 0 1 1 1 1 BAR domain DUF4164 PF13747.1 EMG47429.1 - 0.27 11.3 1.8 1.1 9.4 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF1227 PF06777.6 EMG47431.1 - 1.1e-60 203.5 1.0 2.6e-60 202.3 0.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EMG47431.1 - 1.4e-49 167.8 1.2 2.8e-49 166.8 0.8 1.6 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EMG47431.1 - 1.2e-44 152.2 0.1 3.7e-44 150.6 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD PF00270.24 EMG47431.1 - 0.00044 19.7 0.1 0.13 11.7 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase SNF2_N PF00176.18 EMG47431.1 - 0.0071 15.1 0.1 1.1 7.9 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.10 EMG47431.1 - 0.016 15.0 0.1 3 7.6 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit YtxC PF08812.6 EMG47431.1 - 0.052 13.0 0.1 0.052 13.0 0.1 2.7 4 0 0 4 4 4 0 YtxC-like family ADK PF00406.17 EMG47432.1 - 6.7e-45 152.6 0.0 8e-45 152.3 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EMG47432.1 - 1.4e-10 40.5 0.0 2.5e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 EMG47432.1 - 5.8e-07 29.8 0.0 1.1e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMG47432.1 - 0.00015 22.5 0.0 0.00034 21.4 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 EMG47432.1 - 0.00032 20.5 0.0 0.00078 19.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMG47432.1 - 0.022 13.8 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.5 EMG47432.1 - 0.045 12.9 0.1 0.21 10.7 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Guanylate_kin PF00625.16 EMG47432.1 - 0.097 12.1 0.1 22 4.4 0.0 2.7 3 0 0 3 3 3 0 Guanylate kinase SRP54 PF00448.17 EMG47432.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Leo1 PF04004.8 EMG47433.1 - 6.2e-36 123.6 3.1 6.2e-36 123.6 2.2 3.6 3 2 0 3 3 3 1 Leo1-like protein VWA_3 PF13768.1 EMG47434.1 - 0.0059 16.2 0.0 0.016 14.9 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 EMG47434.1 - 0.012 15.4 9.3 0.044 13.6 4.9 2.6 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 EMG47434.1 - 0.69 9.6 9.3 13 5.5 0.0 2.8 2 0 0 2 2 2 0 zinc-RING finger domain YchF-GTPase_C PF06071.8 EMG47435.1 - 5.5e-05 22.8 0.1 6e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF933) zinc_ribbon_5 PF13719.1 EMG47435.1 - 0.015 14.8 0.2 0.63 9.6 0.0 1.9 1 1 1 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EMG47435.1 - 0.016 14.8 0.3 0.62 9.8 0.0 2.0 1 1 1 2 2 2 0 zinc-ribbon domain p450 PF00067.17 EMG47436.1 - 7.5e-58 196.1 0.1 9.6e-58 195.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Thioredoxin PF00085.15 EMG47437.1 - 6.8e-06 25.7 0.1 1.9e-05 24.2 0.1 1.9 1 1 1 2 2 2 1 Thioredoxin Phosducin PF02114.11 EMG47437.1 - 0.00012 20.9 1.8 0.00014 20.7 1.3 1.1 1 0 0 1 1 1 1 Phosducin BAF1_ABF1 PF04684.8 EMG47438.1 - 0.33 9.7 16.7 0.44 9.3 11.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DTHCT PF08070.6 EMG47438.1 - 0.34 11.6 2.7 0.2 12.3 0.3 1.8 2 0 0 2 2 2 0 DTHCT (NUC029) region Cadherin_C PF01049.12 EMG47438.1 - 0.81 9.7 12.7 0.11 12.4 5.9 1.6 2 0 0 2 2 2 0 Cadherin cytoplasmic region PRELI PF04707.9 EMG47439.1 - 7e-44 149.1 0.5 9.2e-44 148.7 0.4 1.2 1 0 0 1 1 1 1 PRELI-like family DDE_Tnp_ISL3 PF01610.12 EMG47439.1 - 0.014 14.9 0.4 0.019 14.5 0.3 1.2 1 0 0 1 1 1 0 Transposase MutS_V PF00488.16 EMG47441.1 - 1.3e-90 302.8 0.0 2.1e-90 302.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EMG47441.1 - 1.5e-32 113.0 0.6 1.5e-32 113.0 0.4 2.1 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 EMG47441.1 - 5.9e-16 58.4 0.8 5.9e-16 58.4 0.6 2.6 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 EMG47441.1 - 3.6e-11 43.2 5.1 2.2e-10 40.7 0.7 2.7 2 0 0 2 2 2 1 MutS domain II MutS_I PF01624.15 EMG47441.1 - 6.3e-06 26.1 0.6 5.8e-05 23.0 0.1 2.4 2 0 0 2 2 2 1 MutS domain I Ceramidase PF05875.7 EMG47442.1 - 6.5e-67 225.4 2.6 7.4e-67 225.2 1.8 1.1 1 0 0 1 1 1 1 Ceramidase DUF1049 PF06305.6 EMG47442.1 - 0.93 9.0 3.4 0.94 9.0 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF308 PF03729.8 EMG47442.1 - 2.5 8.1 10.0 0.21 11.6 1.3 2.7 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) RNA_pol_Rpb1_5 PF04998.12 EMG47443.1 - 3.9e-95 318.2 0.0 6.5e-95 317.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EMG47443.1 - 3.1e-88 296.2 0.1 4.8e-88 295.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EMG47443.1 - 4e-68 228.5 0.0 2e-67 226.3 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EMG47443.1 - 4.2e-39 133.8 0.0 1.2e-38 132.3 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EMG47443.1 - 1.2e-31 108.6 0.2 7.5e-31 106.0 0.0 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 DUF2786 PF10979.3 EMG47443.1 - 0.011 15.3 0.4 0.026 14.2 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) VHS PF00790.14 EMG47443.1 - 0.042 13.4 0.8 0.1 12.1 0.5 1.6 1 0 0 1 1 1 0 VHS domain COPI_assoc PF08507.5 EMG47444.1 - 2.3e-35 121.2 4.6 2.8e-35 121.0 3.2 1.0 1 0 0 1 1 1 1 COPI associated protein HSA PF07529.8 EMG47445.1 - 4.6e-15 55.1 1.2 4.6e-15 55.1 0.9 4.0 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.1 EMG47445.1 - 2.1e-08 34.1 0.4 2.1e-08 34.1 0.3 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EMG47445.1 - 0.037 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain Nipped-B_C PF12830.2 EMG47446.1 - 2.7e-39 134.7 12.8 3.4e-39 134.4 0.2 4.7 4 1 0 4 4 4 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EMG47446.1 - 6.7e-14 51.4 0.6 2.4e-12 46.5 0.3 3.4 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.1 EMG47446.1 - 0.00012 22.2 0.1 0.026 14.8 0.0 4.0 4 1 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 EMG47446.1 - 3.5 8.2 9.0 44 4.7 0.1 4.9 5 1 1 6 6 6 0 HEAT-like repeat SAS4 PF15460.1 EMG47447.1 - 1.1e-25 89.4 9.4 1.1e-25 89.4 6.5 1.5 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 MCM2_N PF12619.3 EMG47447.1 - 0.016 15.2 8.5 0.015 15.3 5.3 1.4 1 1 0 1 1 1 0 Mini-chromosome maintenance protein 2 Metallophos PF00149.23 EMG47448.1 - 5.5e-15 55.2 4.5 7.5e-15 54.8 3.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMG47448.1 - 0.00042 20.1 0.2 0.00077 19.3 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sec10 PF07393.6 EMG47449.1 - 1.1e-179 599.0 18.5 1.4e-179 598.7 12.8 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 ubiquitin PF00240.18 EMG47450.1 - 1.4e-34 117.3 0.9 2.6e-34 116.4 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EMG47450.1 - 1.9e-28 98.0 1.4 3.5e-28 97.1 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EMG47450.1 - 5.8e-20 70.7 0.7 1e-19 70.0 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EMG47450.1 - 8.9e-06 25.8 0.5 3.8e-05 23.8 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EMG47450.1 - 0.00011 21.9 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EMG47450.1 - 0.0013 18.6 0.4 0.0027 17.5 0.3 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EMG47450.1 - 0.005 17.0 0.4 0.0068 16.5 0.3 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.16 EMG47450.1 - 0.018 14.9 0.6 0.029 14.2 0.4 1.4 1 0 0 1 1 1 0 IBR domain DUF2870 PF11069.3 EMG47450.1 - 0.044 13.8 0.3 0.095 12.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 EMG47450.1 - 0.16 10.2 2.7 3.7 5.7 0.1 2.2 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Spc7 PF08317.6 EMG47451.1 - 0.0013 17.4 15.9 0.0013 17.4 11.0 6.4 1 1 6 7 7 7 3 Spc7 kinetochore protein Reo_sigmaC PF04582.7 EMG47451.1 - 0.41 9.7 29.9 0.29 10.2 1.7 5.1 1 1 1 4 4 4 0 Reovirus sigma C capsid protein MbeD_MobD PF04899.7 EMG47451.1 - 0.62 9.9 24.6 0.78 9.6 0.0 7.3 5 3 3 8 8 8 0 MbeD/MobD like Glycos_transf_3 PF00591.16 EMG47452.1 - 3.2e-80 269.1 0.0 4e-80 268.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EMG47452.1 - 4.7e-11 42.1 0.0 1.1e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Sec63 PF02889.11 EMG47453.1 - 1e-172 573.5 14.2 1.7e-92 309.9 1.2 3.2 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.24 EMG47453.1 - 4.1e-45 153.2 0.1 9.6e-29 100.0 0.1 2.8 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 EMG47453.1 - 5.2e-13 49.2 0.2 8.4e-09 35.5 0.0 3.1 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EMG47453.1 - 1.3e-09 37.8 0.0 4.7e-09 35.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EMG47453.1 - 0.00013 22.0 0.3 0.0044 17.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 EMG47453.1 - 0.00072 19.0 0.0 2.1 7.7 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein PhoH PF02562.11 EMG47453.1 - 0.0066 15.6 0.0 3.5 6.8 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_19 PF13245.1 EMG47453.1 - 0.047 13.4 0.0 7.1 6.4 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain Kelch_1 PF01344.20 EMG47453.1 - 0.062 12.8 0.0 8.4 6.0 0.0 3.0 2 0 0 2 2 2 0 Kelch motif E1_dh PF00676.15 EMG47454.1 - 7.4e-119 395.9 0.6 8.9e-119 395.6 0.4 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EMG47454.1 - 0.0018 17.2 0.0 0.0033 16.4 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.1 EMG47454.1 - 0.0087 16.6 2.8 0.085 13.5 0.1 2.9 2 2 0 2 2 2 1 KRTAP type 7 family DUF3759 PF12585.3 EMG47455.1 - 7.7e-40 134.7 6.1 8.8e-40 134.5 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DPRP PF04244.8 EMG47455.1 - 0.013 15.0 1.4 0.25 10.8 0.2 2.0 1 1 1 2 2 2 0 Deoxyribodipyrimidine photo-lyase-related protein zf-RING_2 PF13639.1 EMG47456.1 - 1.6e-05 24.6 4.2 3.3e-05 23.6 2.9 1.6 1 0 0 1 1 1 1 Ring finger domain Spo7_2_N PF15407.1 EMG47457.1 - 4.3e-18 64.5 2.9 1.8e-17 62.5 0.0 2.9 3 0 0 3 3 3 1 Sporulation protein family 7 PH_4 PF15404.1 EMG47457.1 - 2e-10 40.5 2.2 5.9e-10 38.9 0.2 2.6 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.24 EMG47457.1 - 2e-06 27.9 4.0 0.032 14.4 0.1 3.7 3 0 0 3 3 3 2 PH domain Suc_Fer-like PF06999.7 EMG47458.1 - 1.6e-38 133.0 0.0 2e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Flocculin_t3 PF13928.1 EMG47459.1 - 0.0066 16.5 14.2 0.0066 16.5 9.8 6.6 2 2 1 3 3 3 1 Flocculin type 3 repeat tRNA_anti-like PF12869.2 EMG47459.1 - 0.026 14.0 6.5 2 7.9 0.6 3.1 1 1 2 3 3 3 0 tRNA_anti-like Polysacc_synt_4 PF04669.8 EMG47459.1 - 0.11 11.8 1.1 11 5.3 0.1 2.9 1 1 2 3 3 3 0 Polysaccharide biosynthesis Inh PF02974.9 EMG47459.1 - 0.29 10.7 1.6 7.1 6.2 0.1 3.2 1 1 3 4 4 4 0 Protease inhibitor Inh Pput2613-deam PF14427.1 EMG47459.1 - 1.2 8.8 11.4 2.8 7.6 0.5 3.6 1 1 3 4 4 4 0 Pput_2613-like deaminase DUF4196 PF13846.1 EMG47459.1 - 2.1 8.6 5.6 1.4 9.2 1.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4196) Clusterin PF01093.12 EMG47462.1 - 0.071 11.9 4.5 0.038 12.7 1.8 1.4 2 0 0 2 2 2 0 Clusterin Caleosin PF05042.8 EMG47462.1 - 0.072 12.6 0.2 0.2 11.1 0.2 1.7 1 0 0 1 1 1 0 Caleosin related protein SDA1 PF05285.7 EMG47462.1 - 0.88 8.7 7.0 1.2 8.3 4.9 1.1 1 0 0 1 1 1 0 SDA1 Sof1 PF04158.9 EMG47463.1 - 0.011 15.7 1.0 0.044 13.7 0.7 2.0 1 0 0 1 1 1 0 Sof1-like domain TPR_1 PF00515.23 EMG47464.1 - 3e-23 80.4 14.6 1.1e-05 24.7 0.5 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 EMG47464.1 - 6.2e-20 70.6 13.9 6.6e-10 38.4 0.2 4.6 2 1 3 5 5 5 4 TPR repeat TPR_2 PF07719.12 EMG47464.1 - 5.2e-18 63.4 14.5 0.0035 17.1 0.0 6.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EMG47464.1 - 4.5e-14 51.0 13.3 0.0033 17.0 0.0 6.1 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMG47464.1 - 6e-11 42.1 4.6 5.8e-05 22.9 0.3 5.0 2 2 4 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EMG47464.1 - 1.1e-10 41.0 0.4 0.00015 22.0 0.0 4.8 3 3 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMG47464.1 - 2.5e-10 40.7 5.4 1e-05 26.0 0.0 4.3 4 1 2 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMG47464.1 - 2.1e-07 30.5 6.6 0.01 15.9 0.0 4.5 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMG47464.1 - 2.7e-06 27.6 2.8 0.96 9.8 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.5 EMG47464.1 - 3.9e-06 25.8 0.0 0.00052 18.8 0.0 2.1 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.1 EMG47464.1 - 7.7e-05 22.4 0.4 0.63 9.9 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EMG47464.1 - 0.00017 21.6 15.2 0.0072 16.4 0.8 3.6 2 2 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EMG47464.1 - 0.0003 20.3 4.0 0.22 11.3 0.1 4.3 6 0 0 6 6 5 2 Tetratricopeptide repeat DUF3856 PF12968.2 EMG47464.1 - 0.035 13.9 0.3 0.61 9.8 0.0 2.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) PTH2 PF01981.11 EMG47464.1 - 0.046 13.4 0.0 0.31 10.7 0.0 2.2 1 1 1 2 2 2 0 Peptidyl-tRNA hydrolase PTH2 DUF1244 PF06844.6 EMG47464.1 - 0.061 13.1 0.7 6 6.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) TPR_6 PF13174.1 EMG47464.1 - 0.063 13.7 14.2 16 6.1 0.0 6.0 6 1 0 6 6 6 0 Tetratricopeptide repeat RPN7 PF10602.4 EMG47464.1 - 0.12 11.7 2.9 4 6.7 0.0 2.8 2 1 0 2 2 2 0 26S proteasome subunit RPN7 Aminotran_1_2 PF00155.16 EMG47465.1 - 4.5e-40 137.7 0.0 5.7e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II zf-C3HC4_3 PF13920.1 EMG47466.1 - 3.5e-06 26.5 11.8 5.8e-06 25.8 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FAM176 PF14851.1 EMG47466.1 - 0.5 10.0 3.3 0.34 10.5 0.8 1.8 2 0 0 2 2 2 0 FAM176 family Arf PF00025.16 EMG47467.1 - 5.9e-79 263.3 0.1 6.8e-79 263.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EMG47467.1 - 3.4e-14 52.5 0.0 3.7e-14 52.4 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EMG47467.1 - 5.7e-14 51.7 0.0 6.7e-14 51.5 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EMG47467.1 - 5e-12 45.2 1.0 6.1e-09 35.0 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EMG47467.1 - 8.9e-12 44.6 0.0 1.1e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EMG47467.1 - 1.3e-09 38.6 0.0 1.6e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMG47467.1 - 3.7e-05 23.6 0.1 4.9e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EMG47467.1 - 0.0073 15.4 0.8 0.021 13.9 0.6 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EMG47467.1 - 0.023 14.1 0.5 0.14 11.6 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EMG47467.1 - 0.098 12.1 0.1 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EMG47467.1 - 0.1 12.0 0.2 0.72 9.2 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EMG47467.1 - 0.11 12.3 0.1 0.17 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EMG47467.1 - 0.13 11.8 0.3 0.38 10.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain SRP54 PF00448.17 EMG47467.1 - 0.18 11.2 0.6 0.52 9.7 0.1 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ECH PF00378.15 EMG47468.1 - 6.2e-18 64.8 0.1 5.3e-17 61.7 0.0 1.8 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase family dTDP_sugar_isom PF00908.12 EMG47468.1 - 0.066 12.5 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase NPR3 PF03666.8 EMG47469.1 - 1.5e-143 478.6 9.9 1.2e-127 426.1 4.7 3.6 3 1 1 4 4 4 2 Nitrogen Permease regulator of amino acid transport activity 3 ECH PF00378.15 EMG47470.1 - 3.2e-13 49.3 0.1 3.7e-13 49.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family PROCN PF08083.6 EMG47471.1 - 6.1e-217 719.9 11.8 9.7e-217 719.2 8.1 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EMG47471.1 - 1.8e-124 413.5 0.6 3.1e-124 412.7 0.4 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EMG47471.1 - 9.3e-87 288.3 0.4 2.4e-86 287.0 0.3 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EMG47471.1 - 3.8e-74 247.4 4.6 4.9e-74 247.0 2.0 2.2 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EMG47471.1 - 4.9e-67 223.7 0.0 1.2e-66 222.4 0.0 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 EMG47471.1 - 1.3e-48 163.7 0.2 3.6e-48 162.4 0.2 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 EMG47471.1 - 5.5e-44 147.9 1.3 1.5e-43 146.5 0.9 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 LMBR1 PF04791.11 EMG47472.1 - 1.2 7.6 4.4 2.1 6.8 3.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Histidinol_dh PF00815.15 EMG47473.1 - 4e-181 602.1 2.6 4e-181 602.1 1.8 1.6 2 0 0 2 2 2 1 Histidinol dehydrogenase TPR_11 PF13414.1 EMG47473.1 - 3.7e-23 80.9 13.8 2.2e-12 46.4 0.1 5.3 3 2 3 6 6 6 5 TPR repeat PRA-CH PF01502.13 EMG47473.1 - 9.9e-22 76.3 0.1 2.1e-21 75.3 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase TPR_1 PF00515.23 EMG47473.1 - 3.2e-20 70.8 6.1 2.9e-06 26.6 0.0 6.9 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 EMG47473.1 - 8.5e-19 66.1 4.6 0.0013 18.7 0.3 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EMG47473.1 - 6.7e-14 50.6 11.6 0.0014 18.3 0.0 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMG47473.1 - 9.1e-14 50.7 3.2 0.0019 18.6 0.0 5.8 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 EMG47473.1 - 4.3e-12 46.1 5.7 0.0064 16.8 0.1 4.9 2 2 2 4 4 4 4 Tetratricopeptide repeat PRA-PH PF01503.12 EMG47473.1 - 7.5e-12 45.3 0.1 7.5e-12 45.3 0.0 2.8 3 0 0 3 3 2 1 Phosphoribosyl-ATP pyrophosphohydrolase TPR_16 PF13432.1 EMG47473.1 - 6.8e-11 42.5 4.2 8.6e-05 23.1 0.0 4.3 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 EMG47473.1 - 2.6e-08 33.6 4.9 9.9e-05 22.2 0.0 4.6 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 EMG47473.1 - 1.8e-07 31.1 0.6 0.042 13.9 0.0 4.8 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMG47473.1 - 5.5e-05 22.6 6.5 1 9.3 0.0 6.8 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMG47473.1 - 7.3e-05 22.5 0.1 0.14 12.0 0.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EMG47473.1 - 0.0023 17.6 1.1 2.7 7.9 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EMG47473.1 - 0.0059 16.7 6.2 0.043 13.9 0.1 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EMG47473.1 - 0.01 16.2 2.7 99 3.7 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat RNR_inhib PF08591.5 EMG47474.1 - 3.9e-14 53.3 0.4 3.8e-12 46.9 0.3 2.2 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor Aminotran_3 PF00202.16 EMG47475.1 - 1.9e-105 352.4 0.0 2.5e-105 352.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EMG47475.1 - 0.0011 17.9 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EMG47475.1 - 0.0014 17.8 0.0 0.0042 16.2 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EMG47476.1 - 8.9e-143 475.2 0.0 1e-142 475.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EMG47476.1 - 3.7e-12 45.9 0.2 1.5e-11 43.9 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EMG47476.1 - 1.9e-08 33.6 0.0 2.8e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EMG47476.1 - 8e-08 31.4 0.2 1.3e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EMG47476.1 - 0.00025 20.2 0.0 0.00049 19.3 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 EMG47476.1 - 0.00055 18.3 0.1 0.00079 17.8 0.1 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 EMG47476.1 - 0.0029 16.3 0.0 0.0041 15.8 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein DEAD PF00270.24 EMG47478.1 - 2.2e-34 118.4 0.1 3.8e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG47478.1 - 7.2e-23 80.2 0.0 2.5e-22 78.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMG47478.1 - 2.5e-07 30.7 0.0 6.7e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EMG47478.1 - 0.014 14.4 0.0 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit T5orf172 PF10544.4 EMG47479.1 - 1.1e-09 38.5 2.0 4.9e-09 36.4 1.4 2.2 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 EMG47479.1 - 4.3e-09 36.6 0.5 9.9e-07 29.1 0.1 2.6 1 1 1 2 2 2 2 Meiotically up-regulated gene 113 JmjC PF02373.17 EMG47480.1 - 6.8e-41 139.1 0.2 2.6e-40 137.2 0.1 2.1 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 EMG47480.1 - 4.8e-12 45.3 6.5 4.8e-12 45.3 4.5 3.1 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.12 EMG47480.1 - 1.2e-11 43.8 0.0 2.8e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 jmjN domain PHD_2 PF13831.1 EMG47480.1 - 0.00083 18.6 3.4 0.0041 16.3 0.5 2.6 2 0 0 2 2 2 1 PHD-finger DUF2318 PF10080.4 EMG47480.1 - 0.17 11.6 2.6 0.98 9.2 0.2 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Prok-RING_1 PF14446.1 EMG47480.1 - 0.96 9.2 7.0 0.16 11.7 1.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 P5CR_dimer PF14748.1 EMG47481.1 - 2.4e-34 117.5 0.7 4.7e-34 116.6 0.5 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EMG47481.1 - 4.1e-14 52.7 0.1 1.2e-13 51.2 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EMG47481.1 - 5.1e-07 29.5 0.2 1.1e-06 28.4 0.2 1.6 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EMG47481.1 - 0.0014 18.0 0.1 0.0027 17.1 0.0 1.5 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA OCD_Mu_crystall PF02423.10 EMG47481.1 - 0.005 15.6 0.1 0.0092 14.7 0.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family ATP-synt_ab PF00006.20 EMG47482.1 - 9.7e-63 211.5 0.0 1.7e-62 210.7 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EMG47482.1 - 2.5e-26 92.3 0.1 4.4e-26 91.5 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EMG47482.1 - 9.9e-24 83.3 1.5 9.9e-24 83.3 1.0 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 EMG47482.1 - 0.0018 17.4 0.2 0.0032 16.6 0.1 1.4 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 EMG47482.1 - 0.0035 16.7 0.6 0.013 14.9 0.0 2.2 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 EMG47482.1 - 0.0078 15.9 0.1 0.59 9.8 0.0 3.0 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EMG47482.1 - 0.029 14.0 0.1 0.074 12.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 EMG47482.1 - 0.031 13.1 0.4 0.52 9.1 0.1 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_16 PF13191.1 EMG47482.1 - 0.035 14.0 0.6 0.24 11.3 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EMG47482.1 - 0.05 12.7 0.1 0.093 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EMG47482.1 - 0.072 13.2 0.0 0.32 11.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EMG47482.1 - 0.082 13.1 0.0 0.57 10.3 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EMG47482.1 - 0.095 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 EMG47482.1 - 0.095 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Ring_hydroxyl_A PF00848.14 EMG47483.1 - 1.9e-29 102.8 0.0 3.3e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 EMG47483.1 - 7.6e-16 57.4 0.1 2.3e-15 55.9 0.0 1.8 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Peptidase_M48 PF01435.13 EMG47484.1 - 2.3e-52 177.7 0.0 3.1e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 SprT-like PF10263.4 EMG47484.1 - 0.028 14.0 0.2 0.081 12.5 0.1 1.7 2 0 0 2 2 2 0 SprT-like family DUF955 PF06114.8 EMG47484.1 - 0.057 13.1 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF955) DUF2268 PF10026.4 EMG47484.1 - 0.061 12.6 0.1 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) DUF2201_N PF13203.1 EMG47484.1 - 0.17 10.9 0.6 0.29 10.2 0.4 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Glyco_transf_34 PF05637.7 EMG47485.1 - 1.2e-68 231.1 1.7 1.5e-68 230.9 1.2 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family ARID PF01388.16 EMG47486.1 - 8.5e-11 41.5 0.1 8.5e-11 41.5 0.0 2.4 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain DUF999 PF06198.6 EMG47486.1 - 0.011 15.5 0.1 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF999) ATP-synt_E PF05680.7 EMG47487.1 - 6.3e-16 58.1 0.3 6.8e-16 57.9 0.2 1.0 1 0 0 1 1 1 1 ATP synthase E chain Pex2_Pex12 PF04757.9 EMG47488.1 - 4.7e-37 127.6 5.2 6.8e-37 127.0 3.6 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EMG47488.1 - 3.1e-10 39.7 10.0 5.4e-10 38.9 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMG47488.1 - 3.2e-09 36.6 10.0 3.2e-09 36.6 6.9 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMG47488.1 - 1e-08 34.6 8.3 1.8e-08 33.8 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMG47488.1 - 2.9e-07 30.0 9.7 4.4e-07 29.4 6.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMG47488.1 - 1.6e-05 24.5 5.5 2.9e-05 23.7 3.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EMG47488.1 - 0.00026 21.0 7.4 0.00049 20.1 5.1 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EMG47488.1 - 0.00027 20.7 9.7 0.00055 19.7 6.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMG47488.1 - 0.01 15.5 2.2 0.01 15.5 1.5 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 EMG47488.1 - 0.037 13.5 4.2 0.074 12.5 2.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 EMG47488.1 - 0.056 13.2 4.6 0.12 12.1 3.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein BioY PF02632.9 EMG47488.1 - 0.15 11.7 0.7 0.2 11.2 0.1 1.5 2 0 0 2 2 2 0 BioY family zf-Apc11 PF12861.2 EMG47488.1 - 0.17 11.7 5.9 0.27 11.0 4.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EMG47488.1 - 0.8 9.3 10.8 1.6 8.4 7.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.16 EMG47488.1 - 1.1 9.1 7.6 3 7.7 5.3 1.7 1 1 0 1 1 1 0 IBR domain SpoIIE PF07228.7 EMG47489.1 - 1.1e-19 70.8 0.0 1.7e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EMG47489.1 - 1.5e-07 31.1 0.1 0.00047 19.6 0.0 2.2 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EMG47489.1 - 1.7e-06 27.5 0.0 3.8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C DUF4137 PF13593.1 EMG47490.1 - 3.4e-120 400.8 13.6 4.1e-120 400.6 9.4 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 EMG47490.1 - 1.1e-09 37.9 2.5 1.1e-09 37.9 1.7 2.4 2 1 0 2 2 2 1 Sodium Bile acid symporter family Colicin_im PF03857.8 EMG47490.1 - 0.004 16.9 0.7 0.011 15.5 0.2 1.9 2 0 0 2 2 2 1 Colicin immunity protein FYVE PF01363.16 EMG47491.1 - 3.2e-23 81.4 25.4 7.1e-16 57.8 4.0 2.3 2 0 0 2 2 2 2 FYVE zinc finger Prok-RING_1 PF14446.1 EMG47491.1 - 0.0087 15.7 2.6 0.0087 15.7 1.8 3.4 3 1 1 4 4 4 1 Prokaryotic RING finger family 1 zf-AN1 PF01428.11 EMG47491.1 - 0.026 14.3 5.9 0.026 14.3 4.1 3.3 4 0 0 4 4 4 0 AN1-like Zinc finger PC4 PF02229.11 EMG47492.1 - 6.5e-21 73.3 0.2 1.2e-20 72.4 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) CDC45 PF02724.9 EMG47492.1 - 0.24 9.3 6.4 0.23 9.4 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.3 EMG47492.1 - 0.91 9.4 17.7 1.2 8.9 12.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PBP_sp32 PF07222.7 EMG47492.1 - 2.2 7.3 12.6 3 6.9 8.8 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Daxx PF03344.10 EMG47492.1 - 4 5.8 17.5 4.6 5.6 12.1 1.1 1 0 0 1 1 1 0 Daxx Family Pox_Ag35 PF03286.9 EMG47492.1 - 4.3 6.8 15.2 6.2 6.2 10.5 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sec62 PF03839.11 EMG47492.1 - 6.5 6.1 7.4 8.7 5.6 5.1 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Aldo_ket_red PF00248.16 EMG47493.1 - 1.1e-49 168.7 0.0 1.2e-49 168.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FCH PF00611.18 EMG47494.1 - 1.3e-16 60.5 0.4 1.3e-16 60.5 0.3 2.5 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EMG47494.1 - 9.6e-08 31.2 0.0 2.2e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMG47494.1 - 6.2e-07 28.8 0.0 1.7e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF2986 PF11661.3 EMG47494.1 - 5.4 7.4 8.9 0.22 11.8 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) IZUMO PF15005.1 EMG47494.1 - 7.4 6.5 11.8 0.33 11.0 3.2 2.3 1 1 2 3 3 3 0 Izumo sperm-egg fusion muHD PF10291.4 EMG47495.1 - 1.2e-59 201.6 0.1 1.2e-59 201.6 0.1 1.9 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain Bap31 PF05529.7 EMG47496.1 - 3.4e-50 170.1 8.0 4.3e-50 169.8 5.6 1.1 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Fumarate_red_D PF02313.12 EMG47496.1 - 1.5 8.7 4.1 0.42 10.5 0.5 1.7 2 0 0 2 2 2 0 Fumarate reductase subunit D MpPF26 PF07666.6 EMG47496.1 - 4.6 7.1 9.2 2.6 7.9 1.2 2.1 1 1 1 2 2 2 0 M penetrans paralogue family 26 CorA PF01544.13 EMG47497.1 - 2.2e-43 148.3 1.3 7.8e-23 80.9 0.1 3.8 3 1 0 3 3 3 3 CorA-like Mg2+ transporter protein A_thal_3526 PF09713.5 EMG47497.1 - 0.065 13.3 0.1 0.18 11.9 0.1 1.8 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) OPT PF03169.10 EMG47498.1 - 7.4e-136 454.1 43.5 8.4e-136 453.9 30.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Ammonium_transp PF00909.16 EMG47499.1 - 1.6e-118 395.7 30.0 1.8e-118 395.5 20.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF1117 PF06547.7 EMG47499.1 - 0.097 12.7 0.4 0.2 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) DUF3185 PF11381.3 EMG47499.1 - 2.7 7.8 10.5 18 5.1 0.3 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) AA_permease_2 PF13520.1 EMG47500.1 - 3.1e-59 200.5 42.1 1.3e-58 198.6 29.2 1.7 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMG47500.1 - 1.9e-09 36.3 31.5 1.9e-09 36.3 21.8 1.6 2 0 0 2 2 2 1 Amino acid permease zf-RING_5 PF14634.1 EMG47501.1 - 1.1e-07 31.3 7.5 2.2e-07 30.4 5.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMG47501.1 - 2.1e-06 27.6 9.8 4.3e-06 26.6 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMG47501.1 - 2.7e-06 27.0 8.7 4.5e-06 26.3 6.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMG47501.1 - 8.1e-06 25.4 9.4 1.8e-05 24.3 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMG47501.1 - 6.3e-05 22.5 8.4 0.00011 21.8 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMG47501.1 - 0.00047 19.8 6.8 0.0017 18.0 4.7 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EMG47501.1 - 0.0041 16.9 4.8 0.0041 16.9 3.3 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EMG47501.1 - 2.8 7.5 8.9 41 3.8 4.6 3.0 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 ANTH PF07651.11 EMG47502.1 - 7.5e-64 215.1 4.0 7.5e-64 215.1 2.8 1.7 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.15 EMG47502.1 - 1.2e-07 31.5 0.7 4.7e-07 29.7 0.5 2.1 1 0 0 1 1 1 1 ENTH domain Pentapeptide_4 PF13599.1 EMG47502.1 - 0.00069 19.3 0.0 0.0019 17.9 0.0 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 EMG47502.1 - 0.006 15.7 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Rhodanese PF00581.15 EMG47503.1 - 7.7e-10 39.1 0.0 1.3e-09 38.3 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain CTP_transf_2 PF01467.21 EMG47504.1 - 3.3e-26 92.2 0.1 9.4e-26 90.7 0.0 1.8 2 0 0 2 2 2 1 Cytidylyltransferase RRN3 PF05327.6 EMG47504.1 - 2.3 6.2 9.6 3.8 5.5 6.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 EMG47504.1 - 6.1 4.7 17.4 14 3.6 12.1 1.5 1 0 0 1 1 1 0 CDC45-like protein DUF2404 PF10296.4 EMG47505.1 - 4.5e-10 39.5 0.0 9.2e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) IBN_N PF03810.14 EMG47506.1 - 4.8e-13 48.8 0.3 2.1e-12 46.7 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cnd3 PF12719.2 EMG47506.1 - 0.058 12.3 2.1 0.77 8.6 0.2 2.7 2 1 1 3 3 3 0 Nuclear condensing complex subunits, C-term domain SurE PF01975.12 EMG47507.1 - 4.8e-07 29.2 0.1 0.00017 20.9 0.0 2.8 2 1 0 2 2 2 2 Survival protein SurE Prok-E2_E PF14462.1 EMG47507.1 - 0.03 13.9 0.0 0.089 12.3 0.0 1.8 1 0 0 1 1 1 0 Prokaryotic E2 family E DUF4137 PF13593.1 EMG47508.1 - 3.4e-116 387.7 19.1 4.1e-116 387.4 13.2 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 EMG47508.1 - 3.1e-08 33.2 4.9 3.1e-08 33.2 3.4 2.3 2 1 0 2 2 2 1 Sodium Bile acid symporter family DUF4065 PF13274.1 EMG47510.1 - 0.15 12.7 1.6 0.21 12.2 1.1 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4065) LRR_4 PF12799.2 EMG47512.1 - 0.0096 15.5 3.7 12 5.6 0.4 3.8 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) Cyc-maltodext_C PF10438.4 EMG47512.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain LRR_8 PF13855.1 EMG47512.1 - 0.15 11.8 4.6 8.5 6.2 0.0 3.5 2 1 1 3 3 3 0 Leucine rich repeat Ion_trans_2 PF07885.11 EMG47513.1 - 7.2e-27 92.9 39.9 4.7e-17 61.4 5.6 4.1 4 0 0 4 4 4 2 Ion channel Metallophos_3 PF14582.1 EMG47513.1 - 0.029 13.5 1.4 0.051 12.7 1.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily DUF2457 PF10446.4 EMG47513.1 - 2.5 6.7 11.8 3.9 6.0 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF373 PF04123.8 EMG47513.1 - 8.6 5.2 18.4 2.8 6.8 9.3 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF373) Nucleoside_tran PF01733.13 EMG47514.1 - 1.1e-56 192.2 8.2 1.1e-56 192.2 5.7 1.7 2 0 0 2 2 2 1 Nucleoside transporter NDUF_B12 PF08122.7 EMG47514.1 - 0.11 12.2 0.0 0.6 9.8 0.0 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family DUF4131 PF13567.1 EMG47514.1 - 0.47 9.8 0.0 0.47 9.8 0.0 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF4131) Aminotran_1_2 PF00155.16 EMG47516.1 - 3.2e-54 184.2 0.0 3.7e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EMG47516.1 - 0.0052 15.1 0.1 0.012 13.9 0.0 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.8 EMG47516.1 - 0.11 11.1 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Allinase Ribosomal_S17 PF00366.15 EMG47517.1 - 3.2e-09 36.6 2.6 6.6e-09 35.6 1.8 1.6 1 0 0 1 1 1 1 Ribosomal protein S17 U-box PF04564.10 EMG47517.1 - 0.099 12.6 0.5 0.48 10.4 0.1 2.5 2 1 0 2 2 2 0 U-box domain TPR_11 PF13414.1 EMG47518.1 - 4.3e-10 39.0 0.1 5.5e-06 25.9 0.1 2.2 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EMG47518.1 - 2.7e-07 29.9 1.9 0.0042 16.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMG47518.1 - 2.8e-07 29.8 2.5 0.00011 21.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMG47518.1 - 7.3e-07 28.9 0.0 3.9e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMG47518.1 - 0.00097 18.7 0.4 0.38 10.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMG47518.1 - 0.028 14.2 0.3 4.6 7.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EMG47518.1 - 0.072 13.2 0.1 0.17 12.0 0.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EMG47518.1 - 0.14 12.8 0.0 19 6.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EMG47518.1 - 0.15 12.8 0.7 20 5.9 0.3 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Rad1 PF02144.11 EMG47519.1 - 1.5e-54 184.6 10.1 1.9e-54 184.3 7.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 PCNA_C PF02747.10 EMG47519.1 - 0.0012 18.7 1.3 0.0018 18.1 0.2 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain vATP-synt_AC39 PF01992.11 EMG47520.1 - 2.7e-85 286.4 0.4 3e-85 286.2 0.3 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit tRNA-synt_His PF13393.1 EMG47520.1 - 0.019 14.0 0.0 0.035 13.1 0.0 1.5 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Dor1 PF04124.7 EMG47521.1 - 4.4e-19 68.1 16.5 6.9e-19 67.4 11.5 1.2 1 0 0 1 1 1 1 Dor1-like family SNF2_N PF00176.18 EMG47522.1 - 1e-62 211.6 0.2 1.9e-62 210.7 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMG47522.1 - 6.5e-14 51.5 0.0 1.5e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EMG47522.1 - 0.00038 20.1 7.2 0.00093 18.8 5.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EMG47522.1 - 0.00059 19.6 6.0 0.0014 18.3 4.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EMG47522.1 - 0.0011 18.7 4.7 0.0035 17.1 3.2 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMG47522.1 - 0.0016 18.0 3.0 0.006 16.2 2.1 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EMG47522.1 - 0.0025 17.8 6.6 0.0059 16.6 4.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 EMG47522.1 - 0.01 15.3 0.3 0.064 12.7 0.0 2.5 2 1 0 2 2 2 0 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 EMG47522.1 - 0.029 14.0 6.7 0.076 12.6 4.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EMG47522.1 - 0.077 12.9 4.0 0.2 11.5 2.8 1.7 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_4 PF14570.1 EMG47522.1 - 0.41 10.2 7.5 1.1 8.9 5.2 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Beta-lactamase PF00144.19 EMG47523.1 - 5.5e-45 153.8 0.0 8.4e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase TFR_dimer PF04253.10 EMG47524.1 - 1.2e-13 50.7 0.3 2.4e-13 49.7 0.2 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EMG47524.1 - 0.0001 22.0 0.0 0.00019 21.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EMG47524.1 - 0.0042 16.7 0.0 0.025 14.2 0.0 2.1 2 0 0 2 2 2 1 PA domain DNA_ligase_OB PF03120.11 EMG47524.1 - 0.0048 16.5 0.1 0.0098 15.5 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain ChaC PF04752.7 EMG47525.1 - 2.2e-41 141.7 0.0 2.9e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein AIG2 PF06094.7 EMG47525.1 - 0.11 13.0 0.4 0.54 10.7 0.2 2.1 1 1 0 1 1 1 0 AIG2-like family YolD PF08863.5 EMG47526.1 - 4.6 7.1 9.0 1.8 8.4 3.3 2.3 2 1 0 2 2 2 0 YolD-like protein Nha1_C PF08619.5 EMG47527.1 - 3.2e-90 303.4 38.2 3.8e-90 303.2 26.5 1.0 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 EMG47527.1 - 9.5e-69 231.7 28.8 1.1e-68 231.4 20.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EMG47527.1 - 0.27 11.2 1.3 0.65 9.9 0.3 2.1 2 0 0 2 2 2 0 YrhC-like protein CFEM PF05730.6 EMG47528.1 - 1.7e-10 40.5 5.2 2.6e-10 39.9 3.6 1.3 1 0 0 1 1 1 1 CFEM domain Glyco_hydro_72 PF03198.9 EMG47529.1 - 2.8e-129 430.6 2.6 4.4e-129 429.9 1.8 1.3 1 0 0 1 1 1 1 Glucanosyltransferase DUF2629 PF10945.3 EMG47529.1 - 0.03 13.6 0.1 0.064 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2629) FAD_binding_8 PF08022.7 EMG47530.1 - 1.9e-18 66.2 0.1 4.1e-18 65.1 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EMG47530.1 - 1.7e-17 63.7 0.1 2.8e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMG47530.1 - 3.9e-11 43.1 13.7 7.4e-11 42.2 9.5 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component DUF4405 PF14358.1 EMG47530.1 - 0.0065 16.5 10.4 0.43 10.7 1.9 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4405) CFEM PF05730.6 EMG47531.1 - 4.7e-11 42.3 3.9 7.2e-11 41.7 2.7 1.3 1 0 0 1 1 1 1 CFEM domain DUF1036 PF06282.6 EMG47532.1 - 0.066 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1036) YbgS PF13985.1 EMG47534.1 - 0.14 12.0 1.2 0.19 11.6 0.4 1.5 1 1 1 2 2 2 0 YbgS-like protein CFEM PF05730.6 EMG47535.1 - 2e-11 43.5 5.7 3.5e-11 42.7 3.9 1.4 1 0 0 1 1 1 1 CFEM domain MIP-T3 PF10243.4 EMG47537.1 - 2 6.8 22.1 2.4 6.5 15.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 FAM196 PF15265.1 EMG47537.1 - 2.6 7.1 20.1 3 6.9 13.9 1.0 1 0 0 1 1 1 0 FAM196 family CENP-T PF15511.1 EMG47537.1 - 3.7 6.6 24.8 4.4 6.4 17.2 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Asp-B-Hydro_N PF05279.6 EMG47537.1 - 5.6 6.7 20.7 7.1 6.4 14.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Utp14 PF04615.8 EMG47537.1 - 8.7 4.3 20.7 10 4.1 14.4 1.0 1 0 0 1 1 1 0 Utp14 protein Utp11 PF03998.8 EMG47537.1 - 9.8 5.9 11.4 12 5.6 7.9 1.1 1 0 0 1 1 1 0 Utp11 protein SSF PF00474.12 EMG47538.1 - 9.9e-24 83.7 18.2 9.9e-24 83.7 12.6 1.4 1 1 1 2 2 2 1 Sodium:solute symporter family SPC25 PF06703.6 EMG47540.1 - 5.4e-41 139.8 0.9 6.1e-41 139.6 0.6 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF3816 PF12822.2 EMG47540.1 - 0.059 13.2 2.4 0.066 13.1 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) DUF4173 PF13777.1 EMG47540.1 - 0.074 12.3 0.2 0.096 11.9 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4173) Bac_Ubq_Cox PF01654.12 EMG47540.1 - 0.18 10.1 1.0 0.24 9.7 0.7 1.1 1 0 0 1 1 1 0 Bacterial Cytochrome Ubiquinol Oxidase Pput2613-deam PF14427.1 EMG47543.1 - 0.0039 16.8 0.6 0.014 15.0 0.2 1.7 1 1 1 2 2 2 1 Pput_2613-like deaminase DUF3254 PF11630.3 EMG47543.1 - 0.13 12.2 1.9 4 7.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3254) DUF4425 PF14466.1 EMG47543.1 - 0.37 10.9 3.4 0.27 11.3 0.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4425) Big_1 PF02369.11 EMG47543.1 - 2.5 8.0 10.2 6.3 6.7 7.1 1.6 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 1) DUF3617 PF12276.3 EMG47543.1 - 3.5 7.0 7.7 4.5 6.7 5.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3617) ig PF00047.20 EMG47543.1 - 4.9 7.3 8.0 1.2 9.2 2.2 1.9 1 1 1 2 2 2 0 Immunoglobulin domain PTPA PF03095.10 EMG47545.1 - 8.4e-90 300.9 0.0 1.1e-89 300.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Melittin PF01372.12 EMG47545.1 - 1 8.7 3.4 2.5 7.5 2.3 1.7 1 0 0 1 1 1 0 Melittin zf-RING_2 PF13639.1 EMG47546.1 - 2.6e-08 33.5 7.4 6.4e-08 32.3 5.1 1.7 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 EMG47546.1 - 1.6e-06 27.9 4.9 5.3e-06 26.3 3.4 1.9 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.2 EMG47546.1 - 1.7e-06 28.0 4.6 5e-06 26.5 3.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EMG47546.1 - 0.00013 21.7 3.7 0.00033 20.4 2.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EMG47546.1 - 0.0079 16.2 6.4 0.018 15.0 4.5 1.7 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4 PF00097.20 EMG47546.1 - 0.014 15.0 8.6 0.033 13.8 5.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMG47546.1 - 0.11 12.5 10.4 0.11 12.5 6.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 EMG47546.1 - 0.25 11.0 5.0 0.68 9.7 3.5 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2256 PF10013.4 EMG47546.1 - 0.27 11.0 1.7 1.6 8.5 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RING_4 PF14570.1 EMG47546.1 - 0.34 10.5 7.1 2.7 7.6 0.5 3.1 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EMG47546.1 - 0.36 10.8 5.2 0.82 9.7 3.6 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.1 EMG47546.1 - 0.48 10.1 5.1 7.9 6.2 3.6 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SHMT PF00464.14 EMG47547.1 - 2.4e-48 164.5 0.1 2.6e-48 164.3 0.1 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.12 EMG47547.1 - 0.12 11.3 0.0 0.15 11.1 0.0 1.0 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aldo_ket_red PF00248.16 EMG47548.1 - 5.4e-50 169.8 0.0 6.1e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_S10 PF00450.17 EMG47549.1 - 2.2e-135 452.0 0.7 3.2e-135 451.5 0.5 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 EMG47549.1 - 1.3e-30 105.8 1.1 2.2e-30 105.1 0.7 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 EMG47549.1 - 0.13 12.0 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family rRNA_proc-arch PF13234.1 EMG47551.1 - 6.7e-92 307.4 1.9 1.2e-91 306.6 1.3 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 EMG47551.1 - 8.9e-58 194.4 0.1 1.9e-57 193.4 0.1 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EMG47551.1 - 6e-23 81.1 0.0 4.3e-22 78.3 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG47551.1 - 3e-06 26.9 0.0 7.4e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4047 PF13256.1 EMG47551.1 - 0.028 14.3 0.4 0.028 14.3 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4047) Proteasome PF00227.21 EMG47552.1 - 9.6e-41 139.1 0.0 1.2e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF2413 PF10310.4 EMG47553.1 - 5.9e-116 387.8 24.7 6.9e-116 387.6 17.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) DUF922 PF06037.6 EMG47553.1 - 0.017 14.4 5.5 0.45 9.8 1.5 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF922) DUF4175 PF13779.1 EMG47553.1 - 0.041 11.5 4.4 0.067 10.8 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SHMT PF00464.14 EMG47554.1 - 6.8e-48 163.0 0.1 7.4e-48 162.8 0.1 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.12 EMG47554.1 - 0.11 11.5 0.0 0.13 11.2 0.0 1.0 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family BatD PF13584.1 EMG47555.1 - 0.0018 16.9 0.1 0.0022 16.6 0.1 1.1 1 0 0 1 1 1 1 Oxygen tolerance WBP-1 PF11669.3 EMG47555.1 - 0.0066 16.4 0.1 0.0089 16.0 0.0 1.3 1 0 0 1 1 1 1 WW domain-binding protein 1 EphA2_TM PF14575.1 EMG47555.1 - 0.024 15.0 0.0 0.038 14.3 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ASFV_J13L PF05568.6 EMG47555.1 - 0.031 13.8 0.0 0.038 13.5 0.0 1.3 1 1 0 1 1 1 0 African swine fever virus J13L protein DUF3169 PF11368.3 EMG47555.1 - 0.048 12.8 0.0 0.056 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) TMEM154 PF15102.1 EMG47555.1 - 0.05 13.2 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family CcmH PF03918.9 EMG47555.1 - 0.058 12.3 0.2 0.078 11.9 0.1 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein DUF3328 PF11807.3 EMG47555.1 - 0.1 12.3 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DUF912 PF06024.7 EMG47555.1 - 0.17 11.9 1.6 0.23 11.5 0.5 1.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3309 PF11752.3 EMG47555.1 - 0.9 9.3 7.1 0.13 12.1 1.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) DUF3533 PF12051.3 EMG47556.1 - 1.6e-114 382.5 19.9 2.1e-114 382.2 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF1673 PF07895.6 EMG47556.1 - 0.062 12.8 0.1 0.062 12.8 0.1 2.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1673) Med16 PF11635.3 EMG47557.1 - 1.5e-209 697.6 10.6 1.8e-209 697.4 7.3 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 YEATS PF03366.11 EMG47559.1 - 5.5e-32 109.3 1.1 1.3e-31 108.1 0.7 1.6 1 0 0 1 1 1 1 YEATS family NMO PF03060.10 EMG47560.1 - 6.3e-53 180.0 0.0 7.5e-53 179.8 0.0 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EMG47560.1 - 0.00047 19.1 0.0 0.083 11.7 0.0 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.16 EMG47560.1 - 0.064 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.16 EMG47560.1 - 0.078 12.2 0.1 0.23 10.7 0.0 1.8 2 0 0 2 2 2 0 Histidine biosynthesis protein Isochorismatase PF00857.15 EMG47561.1 - 6.5e-20 71.7 0.1 2.4e-18 66.6 0.1 2.0 1 1 0 1 1 1 1 Isochorismatase family Metallophos PF00149.23 EMG47562.1 - 2.7e-13 49.7 1.4 7.5e-13 48.3 1.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMG47562.1 - 1.5e-07 31.4 0.0 2.2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RabGAP-TBC PF00566.13 EMG47563.1 - 1.8e-35 122.3 17.6 6.6e-32 110.7 5.2 2.7 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF3548 PF12068.3 EMG47563.1 - 6.2e-07 28.9 0.1 2.7e-05 23.5 0.1 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3548) Sec7 PF01369.15 EMG47564.1 - 9.4e-34 116.7 3.1 2.2e-33 115.5 2.2 1.6 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EMG47564.1 - 0.0058 16.7 1.4 0.027 14.6 0.0 2.6 2 1 1 3 3 3 1 Pleckstrin homology domain Zip PF02535.17 EMG47564.1 - 0.63 8.9 10.2 1.3 7.9 7.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3533 PF12051.3 EMG47565.1 - 3.6e-111 371.5 21.1 4.4e-111 371.3 14.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) ABC2_membrane_3 PF12698.2 EMG47565.1 - 7e-10 38.4 26.8 9.9e-10 37.9 18.6 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein MatE PF01554.13 EMG47566.1 - 4e-61 205.3 33.2 2.6e-31 108.4 8.5 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EMG47566.1 - 5.7e-07 29.4 4.5 5.7e-07 29.4 3.1 3.9 3 2 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Bystin PF05291.6 EMG47567.1 - 3.9e-123 410.2 0.2 8.2e-123 409.1 0.2 1.5 1 0 0 1 1 1 1 Bystin PI-PLC-X PF00388.14 EMG47567.1 - 1.5e-57 193.1 0.0 5.5e-57 191.2 0.0 2.1 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EMG47567.1 - 2.7e-44 149.9 1.8 1.7e-43 147.3 0.0 2.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EMG47567.1 - 0.0055 16.6 0.1 0.0055 16.6 0.1 3.3 3 1 0 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like His_biosynth PF00977.16 EMG47568.1 - 6.4e-46 156.4 0.1 4.7e-45 153.6 0.0 2.4 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EMG47568.1 - 5.2e-21 74.9 0.0 8.4e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EMG47568.1 - 1.6e-05 24.5 0.0 4.6e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain ThiG PF05690.9 EMG47568.1 - 0.0011 18.0 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Peptidase_S51 PF03575.12 EMG47568.1 - 0.077 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 Methyltransf_11 PF08241.7 EMG47569.1 - 0.013 15.9 0.0 0.031 14.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.11 EMG47569.1 - 0.1 10.9 0.6 0.19 10.0 0.0 1.6 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NST1 PF13945.1 EMG47569.1 - 4.7 7.2 16.1 16 5.5 11.2 1.9 1 0 0 1 1 1 0 Salt tolerance down-regulator LRR_4 PF12799.2 EMG47570.1 - 2.2e-09 36.6 24.8 0.00026 20.5 0.4 8.7 5 3 4 9 9 9 5 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EMG47570.1 - 1.4e-06 27.5 14.5 7 7.3 0.0 9.5 9 0 0 9 9 9 2 Leucine rich repeat LRR_8 PF13855.1 EMG47570.1 - 5.7e-06 26.0 21.7 0.007 16.1 1.9 6.5 6 1 0 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 EMG47570.1 - 4.6e-05 23.0 14.6 0.37 11.0 0.0 8.8 10 1 0 10 10 10 1 Leucine Rich repeat LRR_1 PF00560.28 EMG47570.1 - 7.5e-05 22.2 22.3 0.21 11.7 0.2 9.1 7 3 1 8 8 8 3 Leucine Rich Repeat tRNA-synt_2 PF00152.15 EMG47571.1 - 3.7e-74 249.4 0.0 4.8e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EMG47571.1 - 7e-08 32.2 0.1 1.6e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 EMG47571.1 - 0.027 14.0 0.0 0.49 9.9 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) PHP PF02811.14 EMG47572.1 - 2.6e-15 56.6 0.1 5.4e-15 55.6 0.1 1.6 1 1 0 1 1 1 1 PHP domain ProRS-C_1 PF09180.6 EMG47573.1 - 1.6e-26 91.9 1.5 3.7e-26 90.8 1.1 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EMG47573.1 - 4e-21 75.3 0.1 7.7e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMG47573.1 - 5.3e-19 67.9 0.2 2.5e-18 65.7 0.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain tRNA_edit PF04073.10 EMG47573.1 - 0.00015 21.5 0.2 0.00031 20.5 0.1 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Ribosomal_60s PF00428.14 EMG47573.1 - 4 7.9 13.8 0.72 10.2 4.9 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein tRNA-synt_2 PF00152.15 EMG47574.1 - 5.7e-75 252.1 0.2 9.3e-75 251.4 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EMG47574.1 - 2.6e-13 49.6 0.1 5.1e-13 48.6 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.2 EMG47574.1 - 0.0041 16.6 0.3 0.0079 15.6 0.2 1.5 1 0 0 1 1 1 1 tRNA_anti-like Ins134_P3_kin PF05770.6 EMG47574.1 - 0.0048 15.9 0.3 0.0098 14.9 0.0 1.6 2 0 0 2 2 2 1 Inositol 1, 3, 4-trisphosphate 5/6-kinase tRNA_anti_2 PF13742.1 EMG47574.1 - 0.033 14.0 0.0 0.077 12.8 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Lyase_1 PF00206.15 EMG47575.1 - 2.6e-98 329.0 0.0 4e-98 328.4 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EMG47575.1 - 9.1e-26 89.7 0.0 2e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Amidase PF01425.16 EMG47576.1 - 1.1e-85 288.1 0.0 1.3e-85 287.8 0.0 1.1 1 0 0 1 1 1 1 Amidase Mannosyl_trans3 PF11051.3 EMG47577.1 - 2.9e-71 239.9 0.5 5.8e-71 239.0 0.4 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.3 EMG47578.1 - 2.9e-69 233.4 0.1 5.7e-69 232.4 0.0 1.5 2 0 0 2 2 2 1 Mannosyltransferase putative DUF2611 PF11022.3 EMG47578.1 - 0.11 12.5 0.1 0.47 10.5 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2611) Nuc_N PF14448.1 EMG47578.1 - 0.15 11.5 0.1 0.51 9.9 0.1 1.9 1 0 0 1 1 1 0 Nuclease N terminal Peptidase_M16_C PF05193.16 EMG47579.1 - 7.1e-20 71.4 0.6 6.8e-13 48.6 0.0 3.4 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EMG47579.1 - 1.2e-08 34.8 0.0 3.5e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Bromodomain PF00439.20 EMG47580.1 - 1.5e-22 79.3 0.5 5.8e-22 77.4 0.1 2.2 2 0 0 2 2 2 1 Bromodomain zf-Tim10_DDP PF02953.10 EMG47581.1 - 4.8e-22 77.0 4.1 6.6e-22 76.5 2.9 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Pepsin-I3 PF06394.8 EMG47581.1 - 0.02 14.5 0.7 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain DUF1178 PF06676.6 EMG47581.1 - 0.029 14.5 0.2 0.044 13.9 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) Phasin_2 PF09361.5 EMG47581.1 - 0.042 13.8 0.1 0.17 11.9 0.0 1.8 1 1 1 2 2 2 0 Phasin protein Mmp37 PF09139.6 EMG47581.1 - 0.063 12.2 0.3 0.063 12.2 0.2 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 Ku_PK_bind PF08785.6 EMG47581.1 - 0.15 11.9 1.6 0.17 11.7 1.1 1.1 1 0 0 1 1 1 0 Ku C terminal domain like E_Pc_C PF06752.7 EMG47581.1 - 3.1 7.2 5.1 0.42 10.0 0.2 1.8 1 1 1 2 2 2 0 Enhancer of Polycomb C-terminus DUF2116 PF09889.4 EMG47581.1 - 10 6.0 8.0 1.5 8.7 1.0 2.5 1 1 2 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) NAD_binding_10 PF13460.1 EMG47582.1 - 0.0052 16.8 0.0 0.0068 16.4 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 EMG47582.1 - 0.0067 16.3 0.0 0.008 16.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EMG47582.1 - 0.014 15.6 0.1 0.02 15.2 0.0 1.4 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EMG47582.1 - 0.044 13.2 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EMG47582.1 - 0.069 12.3 0.0 0.073 12.3 0.0 1.1 1 0 0 1 1 1 0 NmrA-like family Abhydrolase_6 PF12697.2 EMG47585.1 - 5.5e-25 88.5 0.0 7.6e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMG47585.1 - 2.3e-19 69.8 0.0 1.5e-18 67.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMG47585.1 - 5.3e-11 42.4 0.0 2.9e-10 40.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EMG47585.1 - 0.00056 19.5 0.0 0.0015 18.1 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EMG47585.1 - 0.0011 18.7 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF2305 PF10230.4 EMG47585.1 - 0.021 14.2 0.0 0.052 12.9 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Thioesterase PF00975.15 EMG47585.1 - 0.051 13.7 0.1 0.39 10.8 0.0 2.4 4 0 0 4 4 4 0 Thioesterase domain Isochorismatase PF00857.15 EMG47586.1 - 8.5e-21 74.6 0.2 2.8e-20 72.9 0.2 1.8 1 1 0 1 1 1 1 Isochorismatase family Isy1 PF06246.7 EMG47587.1 - 1.9e-54 184.8 2.1 2.1e-54 184.6 1.5 1.0 1 0 0 1 1 1 1 Isy1-like splicing family DUF3313 PF11769.3 EMG47587.1 - 0.093 12.0 0.1 0.13 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) NUC153 PF08159.7 EMG47588.1 - 2.7e-15 55.6 1.9 5.8e-15 54.5 1.3 1.6 1 0 0 1 1 1 1 NUC153 domain DUF1977 PF09320.6 EMG47589.1 - 6.7e-27 93.8 0.3 6.7e-27 93.8 0.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 EMG47589.1 - 1.4e-25 88.7 1.3 1.8e-25 88.4 0.2 1.7 2 0 0 2 2 2 1 DnaJ domain Lant_dehyd_N PF04737.8 EMG47590.1 - 0.13 12.2 1.0 0.62 10.1 0.0 2.5 4 0 0 4 4 4 0 Lantibiotic dehydratase, N terminus FAP PF07174.6 EMG47591.1 - 0.35 10.1 19.0 0.38 9.9 13.2 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) NAPRTase PF04095.11 EMG47593.1 - 3.8e-62 209.7 0.3 4.8e-62 209.4 0.2 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family WD40 PF00400.27 EMG47594.1 - 4.4e-26 89.7 4.7 8.6e-06 25.4 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EMG47594.1 - 1e-19 70.1 0.2 3.4e-19 68.5 0.1 2.0 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Vps55 PF04133.9 EMG47595.1 - 1.1e-32 112.2 5.0 1.4e-32 111.9 3.5 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF2108 PF09881.4 EMG47595.1 - 0.0071 16.1 0.3 0.0071 16.1 0.2 2.8 2 2 1 4 4 4 1 Predicted membrane protein (DUF2108) Abi PF02517.11 EMG47595.1 - 0.23 11.6 5.6 0.64 10.1 3.9 1.8 1 1 0 1 1 1 0 CAAX protease self-immunity DUF2614 PF11023.3 EMG47595.1 - 2.4 7.9 8.6 0.87 9.3 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) Oxidored_q2 PF00420.19 EMG47595.1 - 4.4 6.9 8.9 0.32 10.5 0.2 2.4 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L SdpI PF13630.1 EMG47595.1 - 5.4 6.7 12.4 5.5 6.7 0.7 2.3 2 0 0 2 2 2 0 SdpI/YhfL protein family DUF3307 PF11750.3 EMG47595.1 - 7 6.3 9.6 2.2 8.0 0.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3307) THUMP PF02926.12 EMG47596.1 - 1.4e-18 67.1 1.1 1.8e-18 66.8 0.3 1.5 1 1 0 1 1 1 1 THUMP domain Peptidase_C1 PF00112.18 EMG47596.1 - 0.013 15.4 0.4 0.07 12.9 0.0 2.1 1 1 2 3 3 3 0 Papain family cysteine protease HSP70 PF00012.15 EMG47598.1 - 2.8e-218 725.7 13.1 3.2e-218 725.5 9.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMG47598.1 - 2.6e-17 62.4 4.4 9.7e-16 57.2 1.2 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EMG47598.1 - 0.00024 20.7 0.0 0.00049 19.7 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EMG47598.1 - 0.0016 18.2 7.0 0.29 10.9 1.4 4.2 3 1 0 3 3 3 1 Cell division protein FtsA StbA PF06406.6 EMG47598.1 - 0.039 12.9 2.9 1 8.2 0.4 2.8 2 1 0 2 2 2 0 StbA protein Toxin_42 PF15522.1 EMG47598.1 - 0.061 12.5 0.1 0.8 8.8 0.0 2.2 2 0 0 2 2 2 0 Putative toxin 42 Phage_Gp19 PF09355.5 EMG47598.1 - 0.094 12.5 0.2 0.31 10.8 0.0 2.0 2 0 0 2 2 2 0 Phage protein Gp19/Gp15/Gp42 Proteasome PF00227.21 EMG47599.1 - 5.9e-48 162.6 0.1 7.2e-48 162.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMG47599.1 - 1.7e-11 43.2 0.1 2.8e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature FimP PF09766.4 EMG47599.1 - 0.013 14.6 0.5 0.019 14.0 0.3 1.2 1 0 0 1 1 1 0 Fms-interacting protein IBN_N PF03810.14 EMG47600.1 - 1e-12 47.7 0.6 1.1e-11 44.4 0.1 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EMG47600.1 - 8.9e-05 22.4 0.2 8.9e-05 22.4 0.2 4.0 4 0 0 4 4 4 1 Exportin 1-like protein Ribosomal_60s PF00428.14 EMG47601.1 - 0.00061 20.1 0.2 0.00089 19.6 0.1 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein MAM33 PF02330.11 EMG47602.1 - 9.4e-20 71.2 2.8 1.4e-19 70.7 2.0 1.3 1 0 0 1 1 1 1 Mitochondrial glycoprotein Cyclin_N PF00134.18 EMG47603.1 - 1.4e-43 147.4 0.2 3e-43 146.3 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMG47603.1 - 5.4e-30 103.7 1.0 9.8e-30 102.9 0.0 2.0 2 1 0 2 2 2 1 Cyclin, C-terminal domain Flocculin_t3 PF13928.1 EMG47604.1 - 0.00014 21.9 16.5 0.00014 21.9 11.4 3.5 4 1 0 4 4 4 1 Flocculin type 3 repeat ICAP-1_inte_bdg PF10480.4 EMG47604.1 - 0.23 11.1 9.0 0.57 9.9 6.2 1.6 1 0 0 1 1 1 0 Beta-1 integrin binding protein CDK2AP PF09806.4 EMG47605.1 - 0.13 12.5 4.7 0.15 12.2 3.3 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein OGG_N PF07934.7 EMG47606.1 - 5.9e-33 113.3 1.5 1.4e-32 112.0 0.6 1.8 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EMG47606.1 - 7.2e-18 64.8 0.0 1.3e-17 63.9 0.0 1.5 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EMG47606.1 - 0.024 14.3 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Imm33 PF15580.1 EMG47607.1 - 0.00013 21.3 0.0 7.3 6.1 0.0 3.1 3 0 0 3 3 3 3 Immunity protein 33 FTP PF07504.8 EMG47607.1 - 0.00073 18.9 13.5 1.1 8.7 0.2 4.6 3 3 2 5 5 5 3 Fungalysin/Thermolysin Propeptide Motif MHC_I_2 PF14586.1 EMG47607.1 - 0.0083 15.7 0.2 3 7.4 0.0 2.7 1 1 2 3 3 3 2 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 PPV_E2_C PF00511.12 EMG47607.1 - 0.029 14.3 12.1 1.2 9.1 0.2 3.1 1 1 2 3 3 3 0 E2 (early) protein, C terminal DUF2888 PF11135.3 EMG47607.1 - 0.036 13.7 11.5 3.7 7.2 0.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2888) Qn_am_d_aII PF14930.1 EMG47607.1 - 0.037 13.9 5.0 9.6 6.2 0.1 3.0 1 1 2 3 3 3 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II FliC PF12445.3 EMG47607.1 - 1.3 9.1 40.2 3.1 7.9 6.2 3.0 3 0 0 3 3 3 0 Flagellin protein Hyphal_reg_CWP PF11765.3 EMG47609.1 - 3.4e-136 453.3 20.9 3.9e-136 453.2 14.5 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal DUF995 PF06191.7 EMG47609.1 - 0.035 13.5 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF995) UQ_con PF00179.21 EMG47610.1 - 4.8e-48 162.1 0.0 5.6e-48 161.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMG47610.1 - 4.7e-07 29.6 0.2 1.5e-06 28.0 0.0 1.7 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 EMG47610.1 - 0.0071 16.2 0.1 0.015 15.1 0.1 1.7 1 1 0 1 1 1 1 RWD domain Nucleoplasmin PF03066.10 EMG47610.1 - 0.52 9.8 4.5 0.62 9.5 3.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin SPRY PF00622.23 EMG47611.1 - 1.9e-10 40.9 0.1 4.2e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 SPRY domain COX4 PF02936.9 EMG47611.1 - 2.2e-06 27.4 0.5 9.1e-06 25.4 0.1 2.2 2 0 0 2 2 2 1 Cytochrome c oxidase subunit IV DUF1212 PF06738.7 EMG47612.1 - 1.7e-50 171.2 14.0 9.7e-49 165.4 0.4 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EMG47612.1 - 5e-23 81.4 30.5 1.2e-22 80.1 7.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) Peptidase_A8 PF01252.13 EMG47612.1 - 0.56 9.7 5.3 0.6 9.7 0.3 2.3 2 0 0 2 2 2 0 Signal peptidase (SPase) II ANTH PF07651.11 EMG47613.1 - 8.7e-77 257.5 0.0 8.7e-77 257.5 0.0 3.1 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.12 EMG47613.1 - 3.6e-66 221.8 5.7 3.6e-66 221.8 4.0 5.7 5 2 1 6 6 6 1 I/LWEQ domain Med15 PF09606.5 EMG47613.1 - 0.046 11.9 41.3 0.069 11.3 28.6 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Rer1 PF03248.8 EMG47614.1 - 1.1e-82 275.8 4.0 1.3e-82 275.6 2.8 1.0 1 0 0 1 1 1 1 Rer1 family EI24 PF07264.6 EMG47614.1 - 2.2e-05 23.9 0.5 2.7e-05 23.6 0.3 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Ndc1_Nup PF09531.5 EMG47614.1 - 0.06 11.7 1.3 3.5 5.9 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF2208 PF09973.4 EMG47614.1 - 0.54 9.4 4.5 1 8.5 3.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Ribosomal_L27 PF01016.14 EMG47615.1 - 9.4e-31 105.4 0.1 1.5e-30 104.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal L27 protein Spore_III_AB PF09548.5 EMG47615.1 - 0.4 10.4 7.0 0.04 13.6 0.7 2.0 1 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) IZUMO PF15005.1 EMG47615.1 - 1.3 9.0 6.8 1 9.4 1.5 2.5 1 1 2 3 3 3 0 Izumo sperm-egg fusion Peptidase_S46 PF10459.4 EMG47615.1 - 1.6 7.0 7.9 2.2 6.6 5.4 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF4259 PF14078.1 EMG47616.1 - 4.5e-29 101.5 6.6 8.5e-29 100.6 4.6 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4259) PG_binding_4 PF12229.3 EMG47616.1 - 0.014 15.5 3.6 0.023 14.9 1.7 1.8 1 1 1 2 2 2 0 Putative peptidoglycan binding domain DUF1215 PF06744.7 EMG47616.1 - 0.04 13.5 0.2 0.078 12.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1215) Pyr_redox PF00070.22 EMG47616.1 - 0.043 14.2 0.1 7.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF336 PF03928.9 EMG47617.1 - 1.6e-22 79.7 0.0 1.8e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF336) Rcd1 PF04078.8 EMG47618.1 - 8.7e-121 401.7 5.7 1.8e-120 400.6 4.0 1.5 1 1 0 1 1 1 1 Cell differentiation family, Rcd1-like Folliculin PF11704.3 EMG47618.1 - 0.12 12.0 3.3 0.059 12.9 0.5 1.8 2 1 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport RasGEF_N PF00618.15 EMG47618.1 - 0.17 12.0 2.9 1.5 8.9 0.1 2.8 3 0 0 3 3 3 0 RasGEF N-terminal motif CBF PF03914.12 EMG47619.1 - 2.1e-39 134.6 0.4 1.1e-38 132.2 0.0 2.3 2 0 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.6 EMG47619.1 - 1.3e-34 118.2 0.4 1.3e-34 118.2 0.3 3.0 2 0 0 2 2 2 1 Nucleolar complex-associated protein Peptidase_S8 PF00082.17 EMG47620.1 - 2.5e-52 177.8 6.6 3.1e-52 177.4 4.6 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMG47620.1 - 7.8e-14 52.0 0.0 1.7e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 UQ_con PF00179.21 EMG47621.1 - 5.5e-41 139.2 0.0 8.6e-41 138.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMG47621.1 - 0.019 14.7 2.3 0.023 14.4 0.0 2.2 2 1 0 2 2 2 0 Prokaryotic E2 family B UFC1 PF08694.6 EMG47622.1 - 0.015 14.7 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Complex1_49kDa PF00346.14 EMG47623.1 - 3.2e-126 419.8 0.0 4.2e-126 419.5 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit AhpC-TSA PF00578.16 EMG47624.1 - 5.7e-09 35.7 0.0 5.7e-09 35.7 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EMG47624.1 - 0.037 13.5 0.0 0.038 13.5 0.0 1.0 1 0 0 1 1 1 0 Redoxin Proteasome PF00227.21 EMG47625.1 - 2.1e-52 177.2 0.0 2.5e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMG47625.1 - 1.9e-07 30.2 0.6 3.1e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature tRNA-synt_2 PF00152.15 EMG47626.1 - 3.4e-76 256.2 0.0 4.5e-76 255.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EMG47626.1 - 1.1e-08 34.7 0.0 1.8e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EMG47626.1 - 2.8e-07 30.0 0.1 0.00072 18.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EMG47626.1 - 0.019 14.5 0.0 5.4 6.5 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) HALZ PF02183.13 EMG47627.1 - 0.031 13.9 29.1 0.26 11.0 2.2 6.3 6 0 0 6 6 6 0 Homeobox associated leucine zipper SPOUT_MTase PF02590.12 EMG47627.1 - 6.1 6.5 11.5 0.072 12.8 0.3 3.0 2 1 1 3 3 3 0 Predicted SPOUT methyltransferase Mto2_bdg PF12808.2 EMG47627.1 - 9.3 6.4 27.9 0.087 12.9 4.5 4.6 4 1 0 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region eIF2A PF08662.6 EMG47628.1 - 4.3e-39 134.2 0.5 7.2e-36 123.7 0.5 3.0 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 EMG47628.1 - 4e-08 32.7 0.0 9.5e-08 31.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG47628.1 - 3e-07 30.3 0.0 7.6e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG47628.1 - 3.5e-06 26.7 0.0 8.1e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_29 PF03141.11 EMG47628.1 - 0.036 12.3 0.0 0.058 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF1900 PF08954.6 EMG47629.1 - 2e-45 153.6 0.4 4.3e-45 152.5 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EMG47629.1 - 6.7e-34 115.3 0.1 1.3e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EMG47629.1 - 4.2e-26 89.8 1.6 2.1e-07 30.5 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 EMG47629.1 - 1.4e-07 30.0 0.0 0.0037 15.4 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 RasGAP_C PF03836.10 EMG47630.1 - 9.5e-44 148.5 8.4 9.5e-44 148.5 5.8 2.6 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.14 EMG47630.1 - 5.5e-30 104.5 0.8 5.5e-30 104.5 0.6 2.7 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 EMG47630.1 - 7e-07 28.3 13.8 0.13 11.9 0.0 9.1 10 0 0 10 10 10 2 IQ calmodulin-binding motif ATG16 PF08614.6 EMG47630.1 - 0.48 10.2 11.1 0.23 11.2 2.9 2.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Mis14 PF08641.7 EMG47631.1 - 1.5e-13 51.0 6.5 2.2e-13 50.4 4.5 1.3 1 0 0 1 1 1 1 Kinetochore protein Mis14 like Phage_connect_1 PF05135.8 EMG47631.1 - 0.055 13.6 2.9 1.2 9.3 1.6 2.8 1 1 0 1 1 1 0 Phage gp6-like head-tail connector protein Prominin PF05478.6 EMG47631.1 - 0.15 9.6 7.0 0.049 11.1 1.8 1.9 1 1 1 2 2 2 0 Prominin Y_phosphatase3 PF13350.1 EMG47631.1 - 0.16 12.1 1.4 0.29 11.3 0.9 1.7 1 1 0 1 1 1 0 Tyrosine phosphatase family APP_E2 PF12925.2 EMG47631.1 - 0.2 11.2 6.2 0.16 11.4 3.1 1.9 2 1 0 2 2 2 0 E2 domain of amyloid precursor protein TPR_MLP1_2 PF07926.7 EMG47631.1 - 0.3 10.8 7.9 0.25 11.1 3.9 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DNA_topoisoIV PF00521.15 EMG47631.1 - 0.33 9.7 6.8 0.4 9.4 4.7 1.3 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Baculo_PEP_C PF04513.7 EMG47631.1 - 0.85 9.4 7.0 3.6 7.4 3.7 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF148 PF02520.12 EMG47631.1 - 0.97 9.2 7.4 0.26 11.0 1.5 2.3 1 1 1 2 2 2 0 Domain of unknown function DUF148 RRF_GI PF12614.3 EMG47631.1 - 1.3 8.8 5.8 1.3 8.8 1.8 2.5 2 1 1 3 3 3 0 Ribosome recycling factor Astro_capsid PF03115.9 EMG47631.1 - 1.8 6.7 4.8 1.8 6.7 3.3 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF4404 PF14357.1 EMG47631.1 - 9 6.7 9.1 24 5.4 0.1 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) ATP-synt_C PF00137.16 EMG47632.1 - 3.1e-27 94.2 30.9 3.1e-16 59.0 4.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Polysacc_synt_3 PF13440.1 EMG47632.1 - 0.00039 19.9 1.5 0.00039 19.9 1.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein TIP49 PF06068.8 EMG47633.1 - 1.7e-178 593.3 4.4 2e-178 593.1 3.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EMG47633.1 - 1.4e-07 31.8 2.2 0.00019 21.6 0.0 3.0 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EMG47633.1 - 2.8e-07 29.8 2.7 0.00026 20.1 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EMG47633.1 - 0.00013 22.1 0.1 0.18 11.9 0.0 2.7 1 1 1 2 2 2 2 AAA domain DnaB_C PF03796.10 EMG47633.1 - 0.00042 19.2 0.1 0.00087 18.2 0.1 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 EMG47633.1 - 0.00085 19.3 0.1 0.0073 16.3 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EMG47633.1 - 0.0013 18.6 0.1 3.3 7.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 EMG47633.1 - 0.0023 17.1 1.2 0.037 13.2 0.4 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EMG47633.1 - 0.021 14.7 0.1 0.057 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EMG47633.1 - 0.022 14.4 0.1 1.5 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sipho_tail PF05709.6 EMG47633.1 - 0.029 13.5 0.1 0.059 12.5 0.1 1.5 1 0 0 1 1 1 0 Phage tail protein IPT PF01745.11 EMG47633.1 - 0.034 13.3 0.8 1.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_19 PF13245.1 EMG47633.1 - 0.037 13.7 0.1 0.086 12.6 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 EMG47633.1 - 0.038 13.4 0.1 9 5.7 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 EMG47633.1 - 0.038 13.3 0.2 0.075 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EMG47633.1 - 0.11 13.3 0.1 0.29 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain PFK PF00365.15 EMG47634.1 - 2.1e-167 555.1 5.6 1.6e-124 414.4 2.4 2.1 2 0 0 2 2 2 2 Phosphofructokinase Glyoxalase_2 PF12681.2 EMG47634.1 - 0.0014 19.2 0.0 0.0037 17.8 0.0 1.8 1 0 0 1 1 1 1 Glyoxalase-like domain SHOCT PF09851.4 EMG47634.1 - 0.0056 16.1 0.1 0.016 14.6 0.1 1.7 1 0 0 1 1 1 1 Short C-terminal domain UVR PF02151.14 EMG47634.1 - 0.17 11.4 0.4 0.44 10.1 0.3 1.8 1 0 0 1 1 1 0 UvrB/uvrC motif zf-DHHC PF01529.15 EMG47635.1 - 1.3e-33 115.8 12.5 2.1e-33 115.1 7.8 2.0 1 1 0 1 1 1 1 DHHC palmitoyltransferase AhpC-TSA PF00578.16 EMG47637.1 - 8.8e-08 31.8 0.1 9.2e-08 31.8 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EMG47637.1 - 0.0065 16.0 0.0 0.0068 15.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin PALP PF00291.20 EMG47638.1 - 2.5e-61 207.5 0.0 3e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Xpo1 PF08389.7 EMG47639.1 - 1.4e-31 109.4 0.5 1.4e-31 109.4 0.3 4.5 5 0 0 5 5 5 2 Exportin 1-like protein TPT PF03151.11 EMG47641.1 - 4.2e-34 117.4 18.5 4.2e-34 117.4 12.8 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EMG47641.1 - 1.2e-15 57.2 28.8 1.6e-15 56.8 20.0 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EMG47641.1 - 0.0019 18.2 43.0 0.0028 17.6 14.1 2.7 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EMG47641.1 - 0.0043 17.2 2.5 0.0043 17.2 1.7 3.5 2 1 1 3 3 3 1 Multidrug resistance efflux transporter Sec1 PF00995.18 EMG47642.1 - 5.9e-93 312.4 3.2 8.6e-93 311.8 2.2 1.2 1 0 0 1 1 1 1 Sec1 family DUF3694 PF12473.3 EMG47642.1 - 0.048 13.3 0.4 0.096 12.3 0.0 1.7 2 0 0 2 2 2 0 Kinesin protein zf-H2C2_2 PF13465.1 EMG47643.1 - 1.5e-08 34.4 12.7 1.1e-06 28.6 0.6 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMG47643.1 - 4.2e-06 26.7 13.0 0.00024 21.2 2.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMG47643.1 - 4.9e-05 23.3 11.9 0.021 15.1 0.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EMG47643.1 - 0.0094 16.1 8.8 0.095 12.9 0.9 3.0 2 1 0 2 2 2 2 Zinc-finger of C2H2 type RPAP2_Rtr1 PF04181.8 EMG47643.1 - 0.018 15.1 1.4 0.059 13.4 0.9 1.9 1 0 0 1 1 1 0 Rtr1/RPAP2 family zf-C2H2_jaz PF12171.3 EMG47643.1 - 0.1 12.7 4.2 0.66 10.1 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMG47643.1 - 0.79 9.7 3.8 1.4 8.9 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger F-box-like PF12937.2 EMG47645.1 - 1.3e-07 31.2 0.5 3.8e-07 29.7 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMG47645.1 - 1.4e-05 24.6 0.7 3.6e-05 23.2 0.5 1.8 1 0 0 1 1 1 1 F-box domain TauD PF02668.11 EMG47646.1 - 2.9e-57 194.2 0.0 4.6e-57 193.6 0.0 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EMG47646.1 - 0.021 15.2 0.0 0.11 12.9 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF971) CsiD PF08943.5 EMG47646.1 - 0.043 12.7 0.1 0.11 11.4 0.0 1.6 2 0 0 2 2 2 0 CsiD 2OG-FeII_Oxy_3 PF13640.1 EMG47646.1 - 0.078 13.4 0.0 0.36 11.3 0.0 2.1 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily SH2_2 PF14633.1 EMG47647.1 - 1.4e-64 217.1 0.5 3.9e-64 215.7 0.3 1.7 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 EMG47647.1 - 7.3e-31 106.6 1.5 7.3e-31 106.6 1.0 3.1 3 0 0 3 3 3 1 Death-like domain of SPT6 HHH_7 PF14635.1 EMG47647.1 - 1.1e-27 96.1 0.0 3e-27 94.7 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.1 EMG47647.1 - 1.9e-25 89.1 1.5 8.7e-25 87.0 1.0 2.2 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 YqgF PF14639.1 EMG47647.1 - 1.8e-23 82.7 0.0 5.7e-23 81.1 0.0 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 EMG47647.1 - 2.8e-23 81.8 31.8 2.8e-23 81.8 22.0 3.9 2 1 2 4 4 4 1 Acidic N-terminal SPT6 SH2 PF00017.19 EMG47647.1 - 6.2e-07 29.1 0.0 2.3e-06 27.2 0.0 2.0 1 0 0 1 1 1 1 SH2 domain DUF2534 PF10749.4 EMG47647.1 - 0.21 11.5 0.0 0.87 9.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2534) SYF2 PF08231.7 EMG47648.1 - 8.6e-08 32.4 32.5 1.7e-05 24.9 22.6 2.8 1 1 0 1 1 1 1 SYF2 splicing factor DUF1002 PF06207.6 EMG47648.1 - 0.79 9.0 8.9 0.23 10.7 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1002) Methyltransf_3 PF01596.12 EMG47649.1 - 2.1e-17 62.8 0.0 3.5e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EMG47649.1 - 6.5e-09 36.5 0.0 9.1e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMG47649.1 - 0.00043 20.8 0.0 0.00078 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMG47649.1 - 0.043 13.8 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_C57 PF03290.8 EMG47649.1 - 0.055 11.9 0.0 0.081 11.4 0.0 1.2 1 0 0 1 1 1 0 Vaccinia virus I7 processing peptidase Syntaxin-18_N PF10496.4 EMG47650.1 - 8.9e-20 70.3 0.6 8.9e-20 70.3 0.4 2.4 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus GTP_EFTU PF00009.22 EMG47651.1 - 8.8e-44 149.1 0.2 1.8e-43 148.2 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EMG47651.1 - 8.5e-14 51.4 9.4 2.7e-13 49.8 6.5 1.9 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.18 EMG47651.1 - 1.5e-06 28.1 0.0 9e-06 25.6 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.12 EMG47651.1 - 4.7e-06 26.6 0.1 1.7e-05 24.9 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain Miro PF08477.8 EMG47651.1 - 0.00049 20.5 1.1 0.0049 17.3 0.1 3.0 2 1 0 2 2 2 1 Miro-like protein GTP_EFTU_D4 PF14578.1 EMG47651.1 - 0.0062 16.1 0.2 0.026 14.1 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.20 EMG47651.1 - 0.0086 16.1 0.1 0.034 14.2 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 AAA_22 PF13401.1 EMG47651.1 - 0.09 12.9 0.1 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.11 EMG47652.1 - 1.6e-37 129.0 34.3 1.6e-37 129.0 23.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG47652.1 - 6.2e-10 38.2 28.4 1.9e-08 33.3 19.7 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG47653.1 - 3.1e-38 131.3 37.2 3.1e-38 131.3 25.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG47653.1 - 6.5e-11 41.4 25.6 1e-09 37.5 17.7 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter PMT PF02366.13 EMG47654.1 - 3.3e-85 285.3 18.5 3.3e-85 285.3 12.8 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EMG47654.1 - 3.8e-54 183.1 0.1 9.7e-54 181.7 0.0 1.7 1 0 0 1 1 1 1 MIR domain PDCD2_C PF04194.8 EMG47655.1 - 1.7e-36 125.3 0.1 1.7e-36 125.3 0.1 3.3 4 0 0 4 4 4 2 Programmed cell death protein 2, C-terminal putative domain UPF1_Zn_bind PF09416.5 EMG47655.1 - 0.02 14.4 0.1 0.04 13.4 0.1 1.5 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) GTP_EFTU PF00009.22 EMG47656.1 - 9.3e-37 126.2 7.7 1.8e-36 125.3 3.2 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EMG47656.1 - 2.5e-25 88.4 0.7 2.5e-25 88.4 0.5 2.8 3 0 0 3 3 3 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EMG47656.1 - 3.8e-12 46.1 0.2 5.3e-06 26.4 0.0 2.9 2 0 0 2 2 2 2 Elongation factor Tu domain 2 IF2_N PF04760.10 EMG47656.1 - 6.5e-10 38.5 0.0 1.8e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 EMG47656.1 - 3.6e-07 30.1 0.1 1e-06 28.6 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMG47656.1 - 5.1e-06 26.9 2.1 5.6e-06 26.8 0.2 2.1 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMG47656.1 - 0.00068 18.9 0.4 0.0019 17.4 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.17 EMG47656.1 - 0.011 15.1 0.2 0.026 13.9 0.1 1.6 1 0 0 1 1 1 0 Ras family FeoB_N PF02421.13 EMG47656.1 - 0.02 14.1 0.1 0.053 12.7 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.18 EMG47656.1 - 0.031 14.1 2.7 4.4 7.0 0.1 3.2 2 1 1 3 3 3 0 Dynamin family DUF2924 PF11149.3 EMG47656.1 - 0.074 13.0 1.3 0.42 10.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) Dfp1_Him1_M PF08630.5 EMG47657.1 - 8.2e-38 129.0 0.0 2.3e-37 127.5 0.0 1.8 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 EMG47657.1 - 2.3e-22 78.3 2.1 6.4e-22 76.9 1.5 1.8 1 0 0 1 1 1 1 DBF zinc finger Rifin_STEVOR PF02009.11 EMG47658.1 - 0.13 11.9 1.8 0.17 11.4 1.2 1.2 1 0 0 1 1 1 0 Rifin/stevor family Glypican PF01153.14 EMG47658.1 - 0.19 10.2 3.9 0.24 9.9 2.7 1.1 1 0 0 1 1 1 0 Glypican NPR3 PF03666.8 EMG47658.1 - 0.23 9.9 3.3 0.3 9.5 2.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SCRL PF06876.7 EMG47658.1 - 0.59 10.1 5.2 1.3 8.9 3.6 1.6 1 0 0 1 1 1 0 Plant self-incompatibility response (SCRL) protein SRP-alpha_N PF04086.8 EMG47658.1 - 0.64 9.3 6.9 0.85 8.9 4.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Tmemb_cc2 PF10267.4 EMG47658.1 - 1.7 7.1 6.7 1.8 7.0 4.6 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein ApoO PF09769.4 EMG47659.1 - 0.008 15.9 0.3 0.011 15.4 0.2 1.2 1 0 0 1 1 1 1 Apolipoprotein O Phyto_Pns9_10 PF05878.6 EMG47659.1 - 0.27 10.2 2.7 0.35 9.8 1.8 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 DUF4321 PF14209.1 EMG47659.1 - 0.32 10.7 2.2 0.54 9.9 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4321) MSA-2c PF12238.3 EMG47659.1 - 0.57 9.8 8.5 0.76 9.4 5.9 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c SSP160 PF06933.6 EMG47659.1 - 0.95 7.3 21.3 1.4 6.8 14.7 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CFEM PF05730.6 EMG47659.1 - 0.97 9.3 6.8 3.7 7.4 4.7 2.1 1 1 0 1 1 1 0 CFEM domain Orbi_VP6 PF01516.11 EMG47659.1 - 4.6 6.2 9.0 6.3 5.7 6.2 1.1 1 0 0 1 1 1 0 Orbivirus helicase VP6 Macoilin PF09726.4 EMG47659.1 - 7.6 4.6 10.1 9.2 4.4 7.0 1.1 1 0 0 1 1 1 0 Transmembrane protein E1-E2_ATPase PF00122.15 EMG47661.1 - 6.7e-72 241.2 3.0 6.7e-72 241.2 2.1 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMG47661.1 - 4.1e-27 94.8 4.9 4.1e-27 94.8 3.4 3.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMG47661.1 - 2.6e-26 93.3 0.0 1e-24 88.1 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMG47661.1 - 1.4e-17 63.4 0.0 2.7e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EMG47661.1 - 7.4e-15 54.1 0.0 1.9e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EMG47661.1 - 2.2e-14 54.0 0.1 5.3e-14 52.8 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMG47661.1 - 0.00073 19.1 0.9 0.0038 16.8 0.7 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2207 PF09972.4 EMG47661.1 - 4 5.8 9.8 5.8 5.3 0.3 3.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF2422 PF10337.4 EMG47662.1 - 0.83 8.3 2.5 1.3 7.7 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Porin_3 PF01459.17 EMG47663.1 - 2.6e-82 276.2 1.1 3e-82 275.9 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin MFS_1 PF07690.11 EMG47664.1 - 1.1e-17 63.8 23.2 1.4e-17 63.4 16.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4500 PF14937.1 EMG47664.1 - 0.046 13.5 0.9 0.1 12.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) Saw1 PF11561.3 EMG47666.1 - 0.1 11.9 1.1 0.12 11.7 0.8 1.1 1 0 0 1 1 1 0 Single strand annealing-weakened 1 TRAP_alpha PF03896.11 EMG47666.1 - 0.12 11.3 2.2 0.14 11.1 1.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit S-antigen PF05756.6 EMG47666.1 - 2.9 7.9 12.6 7.3 6.6 8.7 1.8 1 1 0 1 1 1 0 S-antigen protein Ribosomal_S24e PF01282.14 EMG47667.1 - 0.014 15.1 0.1 0.044 13.5 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein S24e SH3_1 PF00018.23 EMG47668.1 - 3.2e-10 39.2 0.1 3.2e-10 39.2 0.1 2.0 2 1 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EMG47668.1 - 3.3e-10 39.3 0.1 7.7e-10 38.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMG47668.1 - 6.6e-09 35.1 0.1 1.3e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain RWD PF05773.17 EMG47669.1 - 5.9e-22 77.6 2.7 1.2e-21 76.7 1.9 1.5 1 0 0 1 1 1 1 RWD domain Nucleoplasmin PF03066.10 EMG47669.1 - 0.031 13.7 0.9 0.031 13.7 0.6 2.4 2 1 1 3 3 3 0 Nucleoplasmin Myb_DNA-bind_2 PF08914.6 EMG47669.1 - 0.2 11.4 2.7 0.41 10.4 1.5 1.9 1 1 0 1 1 1 0 Rap1 Myb domain Med9 PF07544.8 EMG47670.1 - 8.6e-12 44.6 0.1 9e-11 41.3 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Rhomboid PF01694.17 EMG47670.1 - 1.4e-10 41.3 13.8 2e-10 40.8 9.6 1.1 1 0 0 1 1 1 1 Rhomboid family MethyltransfD12 PF02086.10 EMG47670.1 - 0.025 14.0 0.1 0.038 13.4 0.1 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Inp1 PF12634.2 EMG47671.1 - 3.2e-28 98.2 0.2 3.2e-28 98.2 0.2 3.4 3 1 1 4 4 4 2 Inheritance of peroxisomes protein 1 MFS_1 PF07690.11 EMG47672.1 - 2.8e-18 65.7 25.8 4.3e-17 61.8 11.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG47672.1 - 1.6e-17 63.2 17.9 2.8e-17 62.4 12.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter WAK PF08488.6 EMG47673.1 - 0.043 14.1 0.0 0.064 13.5 0.0 1.3 1 0 0 1 1 1 0 Wall-associated kinase DUF3806 PF12713.2 EMG47673.1 - 0.079 12.4 0.0 0.15 11.5 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3806) Rad50_zn_hook PF04423.9 EMG47673.1 - 0.15 11.5 0.2 0.62 9.5 0.0 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif MFS_1 PF07690.11 EMG47674.1 - 1.2e-21 76.8 22.3 1.7e-21 76.3 15.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily V_ATPase_I PF01496.14 EMG47674.1 - 0.019 12.8 0.0 0.026 12.3 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Aldedh PF00171.17 EMG47675.1 - 2.8e-77 260.0 0.0 3.7e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CD24 PF14984.1 EMG47675.1 - 0.097 12.4 0.2 0.097 12.4 0.1 2.2 2 0 0 2 2 2 0 CD24 protein MFS_1 PF07690.11 EMG47676.1 - 2.4e-19 69.2 23.2 3.1e-19 68.8 16.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4500 PF14937.1 EMG47676.1 - 0.0033 17.2 1.5 0.026 14.3 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4500) MFS_1 PF07690.11 EMG47677.1 - 1.8e-11 43.3 20.4 2.4e-11 42.9 14.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily V_ATPase_I PF01496.14 EMG47677.1 - 0.087 10.6 0.0 0.12 10.1 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2435 PF10363.4 EMG47678.1 - 5.8e-29 99.8 0.2 4.1e-28 97.1 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 EMG47678.1 - 8.3e-10 37.9 0.3 2.6e-09 36.3 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) HEAT_2 PF13646.1 EMG47678.1 - 5.1e-05 23.4 0.1 0.49 10.7 0.0 2.7 2 0 0 2 2 2 2 HEAT repeats IF-2B PF01008.12 EMG47678.1 - 0.014 14.3 0.3 0.025 13.5 0.2 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family RhodobacterPufX PF11511.3 EMG47678.1 - 0.14 11.5 0.0 0.37 10.2 0.0 1.7 1 0 0 1 1 1 0 Intrinsic membrane protein PufX Ank PF00023.25 EMG47679.1 - 1.4e-14 53.0 0.1 3.5e-10 39.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EMG47679.1 - 1.3e-13 51.0 0.2 3.1e-13 49.8 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMG47679.1 - 1.2e-12 47.6 0.6 1.4e-09 37.8 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMG47679.1 - 5.8e-12 44.6 0.2 1.4e-07 31.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EMG47679.1 - 1.3e-09 38.2 0.0 4.2e-09 36.6 0.1 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ribosomal_L28e PF01778.12 EMG47679.1 - 0.11 12.8 0.1 0.15 12.4 0.1 1.2 1 0 0 1 1 1 0 Ribosomal L28e protein family eIF-5_eIF-2B PF01873.12 EMG47680.1 - 6.6e-45 151.8 0.0 9.6e-45 151.2 0.0 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 IF2_N PF04760.10 EMG47680.1 - 0.018 14.6 0.0 0.094 12.3 0.0 2.2 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region zf-HYPF PF07503.7 EMG47680.1 - 0.15 11.4 0.3 20 4.6 0.0 2.5 2 0 0 2 2 2 0 HypF finger SR-25 PF10500.4 EMG47680.1 - 3.7 6.9 21.3 0.31 10.5 10.7 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 EMG47682.1 - 5e-43 147.1 0.0 1.7e-42 145.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG47682.1 - 2.2e-20 72.8 0.0 3e-13 49.4 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EMG47682.1 - 0.00031 19.8 0.0 0.0014 17.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Aldo_ket_red PF00248.16 EMG47683.1 - 1.6e-47 161.7 0.0 1.9e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.27 EMG47684.1 - 7e-10 38.3 0.0 0.056 13.3 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EMG47684.1 - 0.00036 19.9 0.0 0.28 10.6 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CENP-T PF15511.1 EMG47684.1 - 2.6 7.1 17.8 5.7 6.0 12.3 1.4 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Coiled-coil_56 PF09813.4 EMG47685.1 - 0.014 15.3 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 RNase_HII PF01351.13 EMG47687.1 - 4.5e-53 179.8 0.0 6e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII 2-oxoacid_dh PF00198.18 EMG47688.1 - 7.1e-74 247.9 0.1 9.2e-74 247.5 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EMG47688.1 - 4.9e-17 61.3 0.1 8.9e-17 60.5 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EMG47688.1 - 2.4e-14 52.6 0.4 5.3e-14 51.5 0.3 1.7 1 0 0 1 1 1 1 e3 binding domain His_Phos_1 PF00300.17 EMG47689.1 - 7.5e-22 78.1 0.0 1.3e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TFIIIC_sub6 PF10419.4 EMG47689.1 - 4e-05 22.9 1.1 0.16 11.4 0.0 3.1 3 0 0 3 3 3 2 TFIIIC subunit DUF2874 PF11396.3 EMG47689.1 - 0.21 11.6 3.1 5.2 7.1 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2874) Sec23_trunk PF04811.10 EMG47690.1 - 2.9e-49 167.6 0.6 2.5e-48 164.5 0.4 2.1 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EMG47690.1 - 3e-33 113.3 0.2 6.4e-33 112.2 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EMG47690.1 - 2.1e-29 101.8 0.0 1.8e-28 98.8 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EMG47690.1 - 1.4e-09 37.4 0.0 2.9e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.10 EMG47690.1 - 1.8e-08 33.8 9.6 3.3e-08 32.9 6.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger PE PF00934.15 EMG47690.1 - 0.12 12.5 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 PE family Zn_clus PF00172.13 EMG47691.1 - 2.1e-08 33.9 10.5 4.4e-08 32.9 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APC_CDC26 PF10471.4 EMG47691.1 - 1.1 10.0 27.8 0.92 10.2 6.6 4.0 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 Pyridox_oxase_2 PF12766.2 EMG47693.1 - 1e-29 102.7 0.1 2e-29 101.8 0.1 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 EMG47693.1 - 1.5e-07 31.3 0.0 2.6e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Thioredoxin PF00085.15 EMG47694.1 - 1.1e-54 182.4 1.0 2.2e-27 94.7 0.0 3.8 4 1 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 EMG47694.1 - 2.4e-29 102.4 9.0 2.1e-20 73.3 2.9 4.5 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EMG47694.1 - 3.7e-09 36.5 2.8 0.0098 15.9 0.1 5.5 4 3 2 6 6 6 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EMG47694.1 - 5.1e-09 36.3 13.2 0.00031 20.9 0.1 4.6 4 2 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EMG47694.1 - 8.9e-08 32.0 0.0 0.00027 20.9 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 EMG47694.1 - 8e-06 25.5 1.0 0.11 12.1 0.0 4.1 3 1 0 4 4 4 2 AhpC/TSA family Redoxin PF08534.5 EMG47694.1 - 0.00053 19.5 0.2 0.087 12.3 0.0 2.9 3 0 0 3 3 3 1 Redoxin Thioredoxin_3 PF13192.1 EMG47694.1 - 0.00071 19.3 0.1 2.9 7.7 0.0 3.3 2 0 0 2 2 2 2 Thioredoxin domain CobT PF06213.7 EMG47694.1 - 0.0031 16.7 13.1 0.006 15.7 9.1 1.4 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Thioredoxin_9 PF14595.1 EMG47694.1 - 0.19 11.2 7.3 1.4 8.4 0.0 2.9 3 0 0 3 3 3 0 Thioredoxin WD40 PF00400.27 EMG47695.1 - 8.6e-27 92.0 3.2 1.8e-08 33.9 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat La PF05383.12 EMG47696.1 - 1.4e-15 56.8 1.0 2.2e-15 56.1 0.3 1.6 2 0 0 2 2 2 1 La domain Tim17 PF02466.14 EMG47697.1 - 1.8e-21 76.4 0.0 3.2e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2963 PF11178.3 EMG47697.1 - 0.092 12.1 1.7 0.18 11.2 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2963) YqhR PF11085.3 EMG47697.1 - 0.19 11.2 0.0 0.19 11.2 0.0 2.6 3 0 0 3 3 3 0 Conserved membrane protein YqhR DUF2415 PF10313.4 EMG47699.1 - 3.6e-21 74.5 0.5 9.1e-21 73.2 0.4 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Hexapep PF00132.19 EMG47703.1 - 0.058 12.9 1.1 0.35 10.4 0.0 2.4 2 1 1 3 3 3 0 Bacterial transferase hexapeptide (six repeats) DUF963 PF06131.6 EMG47703.1 - 3.3 7.0 18.6 0.29 10.4 0.3 4.3 4 1 1 5 5 5 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Chitin_bind_4 PF00379.18 EMG47704.1 - 0.0002 21.5 2.2 0.43 10.8 0.1 3.2 2 0 0 2 2 2 2 Insect cuticle protein Hyphal_reg_CWP PF11765.3 EMG47705.1 - 2.9e-154 512.8 15.1 3.3e-154 512.6 10.4 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal PDE8 PF08629.5 EMG47706.1 - 4 7.3 12.3 0.28 10.9 3.6 2.9 2 0 0 2 2 2 0 PDE8 phosphodiesterase Pput2613-deam PF14427.1 EMG47708.1 - 0.0076 15.9 1.8 0.67 9.6 0.1 3.2 2 1 0 3 3 3 1 Pput_2613-like deaminase Chitin_bind_4 PF00379.18 EMG47708.1 - 0.22 11.7 8.6 6.2 7.1 0.3 3.8 3 0 0 3 3 3 0 Insect cuticle protein CBM_5_12_2 PF14600.1 EMG47708.1 - 1 9.0 6.7 8.8 6.0 0.1 3.3 3 0 0 3 3 3 0 Cellulose-binding domain Hyphal_reg_CWP PF11765.3 EMG47709.1 - 8.9e-153 507.9 13.4 1e-152 507.6 9.3 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal RAI16-like PF10257.4 EMG47711.1 - 0.035 13.0 0.2 0.048 12.5 0.2 1.1 1 0 0 1 1 1 0 Retinoic acid induced 16-like protein LRR_4 PF12799.2 EMG47712.1 - 6.5e-48 159.6 99.6 1.2e-06 28.0 4.8 14.1 5 4 8 14 14 14 13 Leucine Rich repeats (2 copies) PP2C PF00481.16 EMG47712.1 - 7.9e-48 163.0 0.2 1.3e-46 159.0 0.0 2.5 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_8 PF13855.1 EMG47712.1 - 1.2e-43 146.6 84.3 3.1e-09 36.4 6.0 9.7 5 2 6 11 11 11 10 Leucine rich repeat Guanylate_cyc PF00211.15 EMG47712.1 - 2e-27 95.7 0.0 5.5e-27 94.3 0.0 1.6 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 EMG47712.1 - 4.5e-22 74.6 84.8 0.23 11.5 0.1 20.1 20 0 0 20 20 20 12 Leucine Rich Repeat RA PF00788.18 EMG47712.1 - 4.3e-11 43.1 0.1 1.4e-10 41.4 0.0 1.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain LRR_7 PF13504.1 EMG47712.1 - 4.6e-08 32.0 73.9 0.26 11.6 0.3 18.7 19 0 0 19 19 18 4 Leucine rich repeat LRR_5 PF13306.1 EMG47712.1 - 0.00014 21.5 19.4 0.059 13.0 4.3 4.8 3 1 1 4 4 4 2 Leucine rich repeats (6 copies) PP2C_2 PF13672.1 EMG47712.1 - 0.00042 19.7 0.0 0.00095 18.6 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_6 PF13516.1 EMG47712.1 - 0.0072 16.2 84.7 4.5 7.6 0.6 19.0 19 1 1 20 20 19 2 Leucine Rich repeat LRR_9 PF14580.1 EMG47712.1 - 0.64 9.5 17.0 0.55 9.7 0.3 4.0 2 1 0 3 3 3 0 Leucine-rich repeat SAPS PF04499.10 EMG47713.1 - 2.1e-182 607.0 7.3 2.1e-182 607.0 5.1 3.1 3 0 0 3 3 3 2 SIT4 phosphatase-associated protein GATase_4 PF13230.1 EMG47714.1 - 1.4e-15 56.7 0.1 5.3e-15 54.8 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EMG47714.1 - 1e-11 44.9 0.0 2.3e-11 43.7 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EMG47714.1 - 6.4e-09 34.9 0.0 3.1e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II DUF1687 PF07955.6 EMG47715.1 - 3.6e-39 133.8 0.8 4.7e-39 133.4 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) ChAPs PF09295.5 EMG47716.1 - 2.2e-28 99.1 1.9 3.6e-24 85.2 0.1 2.7 3 0 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 EMG47716.1 - 0.00032 20.2 0.0 0.00058 19.4 0.0 1.4 1 0 0 1 1 1 1 TPR repeat Septin PF00735.13 EMG47717.1 - 2.4e-79 266.3 4.2 2.4e-79 266.3 2.9 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EMG47717.1 - 4.2e-08 33.1 0.1 1.2e-07 31.6 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMG47717.1 - 9.8e-05 21.5 0.0 0.00017 20.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EMG47717.1 - 0.00022 21.5 0.5 0.0012 19.1 0.0 2.2 2 0 0 2 2 2 1 ABC transporter Miro PF08477.8 EMG47717.1 - 0.0011 19.4 0.5 0.021 15.2 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein AIG1 PF04548.11 EMG47717.1 - 0.0024 17.0 0.0 0.0024 17.0 0.0 1.8 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.22 EMG47717.1 - 0.008 15.6 0.8 0.096 12.1 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EMG47717.1 - 0.0087 15.5 0.2 0.018 14.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EMG47717.1 - 0.09 12.2 0.3 0.09 12.2 0.2 2.1 2 1 0 2 2 2 0 AAA-like domain AAA_16 PF13191.1 EMG47717.1 - 0.44 10.5 2.0 0.45 10.4 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain Coatomer_E PF04733.9 EMG47718.1 - 1.4e-08 34.2 0.6 0.00013 21.2 0.1 2.2 2 0 0 2 2 2 2 Coatomer epsilon subunit cNMP_binding PF00027.24 EMG47719.1 - 7.2e-34 115.4 0.0 5.8e-22 77.3 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ribosomal_L1 PF00687.16 EMG47720.1 - 7e-20 71.3 0.9 9.3e-20 70.9 0.6 1.2 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Gaa1 PF04114.9 EMG47721.1 - 7.7e-87 292.0 0.9 7.7e-87 292.0 0.6 2.1 1 1 1 2 2 2 1 Gaa1-like, GPI transamidase component Apc4 PF12896.2 EMG47722.1 - 1.4e-52 178.0 3.5 2.4e-52 177.2 2.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 EMG47722.1 - 2.7e-09 36.3 0.1 2.7e-08 33.1 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PCI PF01399.22 EMG47722.1 - 0.67 10.2 5.7 5.6 7.3 0.6 3.2 4 0 0 4 4 4 0 PCI domain Hyphal_reg_CWP PF11765.3 EMG47723.1 - 4.5e-84 282.0 13.9 5.1e-84 281.8 9.6 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal ABC_tran PF00005.22 EMG47724.1 - 2.7e-09 37.4 0.0 3e-09 37.2 0.0 1.0 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EMG47724.1 - 0.037 13.2 0.0 0.037 13.2 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Cofilin_ADF PF00241.15 EMG47725.1 - 8.3e-41 138.8 3.2 9.3e-41 138.6 2.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ChlamPMP_M PF07548.6 EMG47725.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain Spore_YabQ PF09578.5 EMG47727.1 - 0.023 14.6 1.1 0.023 14.6 0.8 1.6 1 1 1 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) DUF2892 PF11127.3 EMG47727.1 - 0.99 9.2 4.5 1.1 9.1 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2892) Tetraspannin PF00335.15 EMG47727.1 - 2.3 7.4 7.1 1 8.6 3.1 1.7 1 1 1 2 2 2 0 Tetraspanin family AHS2 PF02626.10 EMG47729.1 - 2.4e-67 227.1 0.0 2.8e-67 226.8 0.0 1.0 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 AHS1 PF02682.11 EMG47730.1 - 9e-23 80.7 0.0 1.1e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 AHS1 PF02682.11 EMG47731.1 - 1.6e-14 53.8 0.2 2.1e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 Hat1_N PF10394.4 EMG47732.1 - 9e-39 133.1 4.0 1.8e-38 132.1 2.8 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_7 PF13508.1 EMG47732.1 - 4.9e-05 23.4 0.0 9.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMG47732.1 - 0.014 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MOZ_SAS PF01853.13 EMG47732.1 - 0.076 12.2 1.1 0.21 10.7 0.8 1.7 1 1 0 1 1 1 0 MOZ/SAS family Rad21_Rec8 PF04824.11 EMG47733.1 - 0.011 14.9 0.1 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein Pil1 PF13805.1 EMG47734.1 - 1.7e-154 512.7 0.6 2e-154 512.5 0.4 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 PCP_red PF08369.5 EMG47734.1 - 0.026 14.4 3.5 0.12 12.2 0.2 2.7 3 0 0 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit V_ATPase_I PF01496.14 EMG47734.1 - 0.32 8.7 1.0 0.42 8.4 0.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HMGL-like PF00682.14 EMG47735.1 - 2.1e-51 174.8 0.3 3.2e-51 174.2 0.2 1.3 1 0 0 1 1 1 1 HMGL-like ADP_PFK_GK PF04587.10 EMG47735.1 - 0.025 12.7 0.0 0.037 12.2 0.0 1.2 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Rsa3 PF14615.1 EMG47736.1 - 1.8e-19 68.7 1.3 1.8e-19 68.7 0.9 1.8 3 0 0 3 3 3 1 Ribosome-assembly protein 3 SOBP PF15279.1 EMG47736.1 - 1.9 8.7 8.7 2.2 8.5 6.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Ndc1_Nup PF09531.5 EMG47736.1 - 8 4.7 11.1 9.6 4.4 7.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SR-25 PF10500.4 EMG47736.1 - 9.6 5.5 23.4 22 4.4 16.2 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein PA PF02225.17 EMG47737.1 - 5.7e-06 25.9 0.0 5.7e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 PA domain Hyphal_reg_CWP PF11765.3 EMG47738.1 - 1.1e-47 162.4 9.4 1.3e-47 162.1 6.5 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Aldo_ket_red PF00248.16 EMG47739.1 - 5.5e-64 215.7 0.0 6.5e-64 215.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hyphal_reg_CWP PF11765.3 EMG47740.1 - 4.2e-48 163.8 10.9 5.2e-48 163.5 7.6 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal RPM2 PF08579.6 EMG47741.1 - 6.3e-37 126.3 2.7 6.3e-37 126.3 1.9 4.2 2 1 1 3 3 3 2 Mitochondrial ribonuclease P subunit (RPM2) PPR_2 PF13041.1 EMG47741.1 - 0.0053 16.7 6.7 0.78 9.7 0.1 4.8 6 0 0 6 6 6 2 PPR repeat family PPR PF01535.15 EMG47741.1 - 0.51 10.4 2.5 6.1 7.0 0.1 4.0 5 0 0 5 5 5 0 PPR repeat TCO89 PF10452.4 EMG47742.1 - 3.4e-11 42.7 22.6 3.3e-08 32.9 0.4 4.4 2 1 2 4 4 4 3 TORC1 subunit TCO89 Metallophos PF00149.23 EMG47743.1 - 3.9e-10 39.4 14.1 3.8e-09 36.2 9.8 2.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMG47743.1 - 0.0032 17.3 1.0 0.012 15.4 0.2 2.2 3 1 0 3 3 3 1 Calcineurin-like phosphoesterase superfamily domain RRM_1 PF00076.17 EMG47745.1 - 3.2e-13 49.1 0.0 5.2e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG47745.1 - 4.2e-12 45.8 0.0 7.4e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG47745.1 - 3.6e-06 26.7 0.0 5.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 EMG47746.1 - 3.4e-20 72.2 0.1 6.7e-20 71.3 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG47746.1 - 1.3e-10 40.8 0.0 2.2e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG47746.1 - 1.3e-05 24.3 0.2 5.3e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like ParcG PF10274.4 EMG47746.1 - 0.011 15.6 6.4 0.017 15.0 0.6 3.3 2 1 1 3 3 3 0 Parkin co-regulated protein FA_hydroxylase PF04116.8 EMG47747.1 - 1.5e-12 47.8 22.8 2.1e-12 47.4 12.8 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily EXS PF03124.9 EMG47748.1 - 3.4e-97 325.5 31.0 5.9e-97 324.7 21.5 1.4 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EMG47748.1 - 7.1e-55 186.7 22.6 7.1e-55 186.7 15.7 2.1 2 0 0 2 2 2 1 SPX domain RseC_MucC PF04246.7 EMG47748.1 - 1.8 8.0 6.2 14 5.2 0.0 2.7 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC ADH_N PF08240.7 EMG47749.1 - 5.8e-30 103.2 1.2 1.1e-29 102.3 0.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMG47749.1 - 1.8e-15 56.6 0.0 3.2e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2314 PF10077.4 EMG47749.1 - 0.056 13.5 0.1 0.38 10.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2314) UPF0016 PF01169.14 EMG47751.1 - 0.15 12.2 2.0 6 7.0 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 Methyltransf_11 PF08241.7 EMG47752.1 - 6.6e-14 52.1 0.0 1.2e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMG47752.1 - 1.3e-09 38.4 0.0 2.7e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMG47752.1 - 3.5e-09 36.1 0.0 5.1e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EMG47752.1 - 8.7e-09 35.2 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMG47752.1 - 4.3e-08 33.7 0.0 7.4e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMG47752.1 - 3.8e-06 26.5 0.0 5.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMG47752.1 - 1.7e-05 25.1 0.0 3.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EMG47752.1 - 0.00048 19.2 0.0 0.0007 18.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EMG47752.1 - 0.0068 16.4 0.0 0.026 14.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMG47752.1 - 0.027 13.8 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Mannosyl_trans3 PF11051.3 EMG47753.1 - 1.6e-69 234.3 0.3 1.6e-69 234.3 0.2 2.2 2 0 0 2 2 2 1 Mannosyltransferase putative OKR_DC_1_N PF03709.10 EMG47753.1 - 0.023 14.7 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain YchF-GTPase_C PF06071.8 EMG47754.1 - 3e-34 116.6 1.4 4.6e-34 116.0 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EMG47754.1 - 2.6e-12 46.7 0.0 1.1e-11 44.6 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 EMG47754.1 - 0.0042 16.8 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 EMG47754.1 - 0.016 14.4 0.0 0.033 13.4 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B SecA_PP_bind PF01043.15 EMG47754.1 - 0.15 12.4 1.4 2.8 8.3 0.0 2.4 2 0 0 2 2 2 0 SecA preprotein cross-linking domain DUF3236 PF11576.3 EMG47754.1 - 0.21 11.0 2.3 0.19 11.1 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3236) Asp PF00026.18 EMG47755.1 - 8.7e-67 225.6 7.0 8.7e-67 225.6 4.9 1.7 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMG47755.1 - 2.7e-12 46.9 0.2 2.7e-12 46.9 0.1 2.3 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMG47755.1 - 0.0006 20.2 3.4 0.52 10.8 0.1 4.2 3 1 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.1 EMG47755.1 - 0.0089 15.5 0.3 0.22 11.0 0.2 2.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EMG47755.1 - 0.041 13.7 0.0 12 5.7 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 EMG47755.1 - 0.074 12.9 0.0 12 5.8 0.0 3.1 3 0 0 3 3 3 0 Retroviral aspartyl protease Ank_2 PF12796.2 EMG47756.1 - 6.9e-20 71.1 1.5 5.3e-11 42.7 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) DIL PF01843.14 EMG47756.1 - 1.2e-15 57.2 8.3 2.4e-13 49.8 0.1 3.2 3 0 0 3 3 3 2 DIL domain Ank PF00023.25 EMG47756.1 - 7.1e-14 50.8 2.6 2.9e-06 26.8 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EMG47756.1 - 2.2e-09 37.2 0.9 0.0022 18.1 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMG47756.1 - 1.8e-08 33.8 2.2 0.00099 19.1 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EMG47756.1 - 6.9e-07 29.6 0.8 0.0052 17.2 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF3447 PF11929.3 EMG47756.1 - 0.1 12.4 4.9 0.16 11.8 0.6 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3447) CIMR PF00878.13 EMG47757.1 - 4.7e-11 42.6 1.7 4.3e-05 23.3 0.1 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.10 EMG47757.1 - 0.0014 17.7 0.1 0.0014 17.7 0.0 1.4 2 0 0 2 2 2 1 Mannose-6-phosphate receptor Adaptin_N PF01602.15 EMG47758.1 - 1.1e-95 320.9 13.9 1.5e-95 320.5 9.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EMG47758.1 - 1.2e-46 158.2 2.4 1.2e-46 158.2 1.7 2.0 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EMG47758.1 - 5e-11 42.7 0.5 0.0055 16.9 0.0 5.3 2 2 6 8 8 8 4 HEAT repeats HEAT_EZ PF13513.1 EMG47758.1 - 4.3e-07 30.2 1.1 0.009 16.4 0.1 4.0 3 0 0 3 3 3 1 HEAT-like repeat Cnd1 PF12717.2 EMG47758.1 - 0.0033 17.2 0.4 0.0033 17.2 0.2 4.7 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EMG47758.1 - 0.0045 16.9 7.3 1.7 8.9 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat Sld5 PF05916.6 EMG47759.1 - 3e-19 69.2 0.2 4.6e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 GINS complex protein DUF619 PF04768.8 EMG47760.1 - 6e-46 155.9 1.5 7.2e-46 155.6 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF619) HlyIII PF03006.15 EMG47761.1 - 4.8e-46 156.9 17.1 5.5e-46 156.7 11.8 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF4231 PF14015.1 EMG47761.1 - 0.034 14.1 0.4 1.7 8.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF2269 PF10027.4 EMG47761.1 - 0.12 12.1 3.0 1.3 8.7 2.4 2.2 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2269) ATP_synt_H PF05493.8 EMG47761.1 - 0.87 9.7 0.0 0.87 9.7 0.0 3.1 2 2 2 4 4 4 0 ATP synthase subunit H DUF3589 PF12141.3 EMG47762.1 - 1.1e-170 568.2 0.7 1.3e-170 567.9 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3589) UBA_2 PF08587.6 EMG47762.1 - 0.021 14.9 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) Cation_efflux PF01545.16 EMG47763.1 - 2.3e-44 151.6 5.0 3.1e-44 151.1 3.4 1.2 1 0 0 1 1 1 1 Cation efflux family CLU PF13236.1 EMG47764.1 - 3.3e-78 262.1 0.0 8.4e-78 260.7 0.0 1.8 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EMG47764.1 - 4.7e-42 143.7 7.1 1.5e-41 142.1 1.5 3.6 2 1 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 EMG47764.1 - 2.7e-16 59.4 1.3 7e-16 58.1 0.2 2.3 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 EMG47764.1 - 1.3e-15 57.0 5.2 1.8e-06 27.7 0.3 4.8 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.1 EMG47764.1 - 1.3e-05 24.9 0.0 2.3 8.2 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMG47764.1 - 0.015 14.9 13.9 0.59 9.8 0.4 4.0 4 0 0 4 4 4 0 TPR repeat TPR_8 PF13181.1 EMG47764.1 - 0.34 10.7 12.2 0.57 10.0 0.2 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2360 PF10152.4 EMG47764.1 - 5 7.3 18.9 0.64 10.2 0.6 3.3 4 0 0 4 4 4 0 Predicted coiled-coil domain-containing protein (DUF2360) F-box-like PF12937.2 EMG47765.1 - 1.2e-11 44.1 0.1 2.2e-11 43.2 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMG47765.1 - 3.7e-09 36.0 0.2 7.5e-09 35.0 0.2 1.6 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 EMG47765.1 - 4e-05 23.3 2.9 0.059 13.2 0.0 4.8 5 0 0 5 5 5 1 WD domain, G-beta repeat IncA PF04156.9 EMG47765.1 - 1.5 8.3 5.2 2.6 7.6 3.6 1.2 1 0 0 1 1 1 0 IncA protein Phosphodiest PF01663.17 EMG47766.1 - 8.8e-15 54.8 0.5 5.2e-14 52.3 0.3 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EMG47766.1 - 0.0012 18.3 0.1 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily zf-C2H2_2 PF12756.2 EMG47767.1 - 1.9e-29 101.7 2.3 5e-29 100.3 1.6 1.7 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EMG47767.1 - 0.17 12.0 5.3 0.059 13.5 1.6 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DNA_pol_A_exo1 PF01612.15 EMG47768.1 - 5.3e-47 159.5 0.8 1.7e-46 157.8 0.1 2.0 2 0 0 2 2 2 1 3'-5' exonuclease PMC2NT PF08066.7 EMG47768.1 - 5.9e-23 80.9 3.5 1.2e-22 80.0 0.4 2.6 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 EMG47768.1 - 6.7e-09 35.3 0.1 2e-08 33.8 0.1 1.8 1 0 0 1 1 1 1 HRDC domain SNARE PF05739.14 EMG47768.1 - 0.58 9.8 3.9 3 7.6 0.1 3.0 3 0 0 3 3 3 0 SNARE domain CLN3 PF02487.12 EMG47769.1 - 2.9e-102 342.4 24.6 3.2e-100 335.7 17.1 2.1 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.11 EMG47769.1 - 2.9e-06 26.2 2.8 2.9e-06 26.2 1.9 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily DAHP_synth_1 PF00793.15 EMG47770.1 - 1.9e-100 335.0 0.0 2.3e-100 334.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF218 PF02698.12 EMG47771.1 - 0.069 12.6 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 DUF218 domain zf-CCCH PF00642.19 EMG47772.1 - 1.8e-10 40.2 9.7 3.5e-05 23.3 1.0 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 EMG47772.1 - 0.00032 20.2 0.0 0.0019 17.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG47772.1 - 0.00097 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AA_permease_2 PF13520.1 EMG47773.1 - 3.3e-51 174.1 40.1 4.2e-51 173.8 27.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMG47773.1 - 4.7e-24 84.5 32.2 6.1e-24 84.1 22.3 1.1 1 0 0 1 1 1 1 Amino acid permease Hydrolase_like PF13242.1 EMG47775.1 - 2.5e-22 78.3 0.2 3.1e-21 74.8 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EMG47775.1 - 4e-19 68.3 0.0 1.2e-18 66.8 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMG47775.1 - 0.00035 21.0 0.0 0.012 16.0 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMG47775.1 - 0.002 18.3 0.2 0.27 11.4 0.0 3.1 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase GATA PF00320.22 EMG47776.1 - 6.3e-15 54.2 3.4 1.4e-14 53.1 2.4 1.6 1 0 0 1 1 1 1 GATA zinc finger CUE PF02845.11 EMG47778.1 - 1.1e-12 47.1 0.0 2.1e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 CUE domain NDUF_B7 PF05676.8 EMG47779.1 - 5.1e-12 45.0 5.0 6.3e-12 44.7 3.5 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) PTN_MK_C PF01091.13 EMG47779.1 - 0.055 13.4 0.9 0.063 13.2 0.1 1.6 2 0 0 2 2 2 0 PTN/MK heparin-binding protein family, C-terminal domain Cmc1 PF08583.5 EMG47779.1 - 0.1 12.3 2.9 0.13 12.0 2.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 EMG47779.1 - 1.2 9.0 5.6 1.6 8.6 1.5 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.11 EMG47779.1 - 1.6 8.7 5.3 2.2 8.3 1.8 2.2 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein RRM_1 PF00076.17 EMG47782.1 - 8.1e-21 73.4 0.1 1.1e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG47782.1 - 1.5e-09 37.7 0.0 1.9e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG47782.1 - 0.002 17.9 0.1 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fascin PF06268.8 EMG47782.1 - 0.059 13.4 0.0 0.081 13.0 0.0 1.2 1 0 0 1 1 1 0 Fascin domain SdiA-regulated PF06977.6 EMG47782.1 - 0.097 11.6 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 SdiA-regulated FtsX PF02687.16 EMG47783.1 - 0.077 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 FtsX-like permease family Trs65 PF12735.2 EMG47784.1 - 6.3e-87 291.7 12.2 6.3e-87 291.7 8.4 2.0 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 LRR_8 PF13855.1 EMG47785.1 - 0.00011 21.8 4.9 0.059 13.1 0.0 3.9 3 1 0 3 3 3 2 Leucine rich repeat F-box-like PF12937.2 EMG47785.1 - 0.00036 20.1 0.0 0.00066 19.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EMG47785.1 - 2.5 7.8 10.8 10 5.8 0.0 5.1 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) Peptidase_M3 PF01432.15 EMG47786.1 - 4.4e-145 484.2 1.2 8.2e-145 483.3 0.8 1.4 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 EMG47786.1 - 0.073 12.4 0.2 0.12 11.7 0.2 1.2 1 0 0 1 1 1 0 Peptidase M50B-like DUF964 PF06133.6 EMG47786.1 - 0.074 13.0 0.5 0.25 11.3 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF964) Peptidase_M91 PF14891.1 EMG47786.1 - 0.35 10.9 2.9 4.1 7.4 0.1 2.4 2 0 0 2 2 2 0 Effector protein tRNA-synt_2b PF00587.20 EMG47787.1 - 6.5e-68 227.6 0.1 3.5e-67 225.3 0.1 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMG47787.1 - 1.7e-23 82.3 0.1 4.3e-23 81.0 0.1 1.8 1 0 0 1 1 1 1 Anticodon binding domain ABA_GPCR PF12430.3 EMG47788.1 - 9e-60 201.1 6.0 9e-60 201.1 4.2 2.2 3 1 0 3 3 3 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 EMG47788.1 - 8.3e-22 77.0 0.1 8.3e-22 77.0 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3735) MscS_TM PF12794.2 EMG47788.1 - 0.015 13.9 0.6 0.015 13.9 0.4 2.6 3 1 1 4 4 4 0 Mechanosensitive ion channel inner membrane domain 1 Mhr1 PF12829.2 EMG47789.1 - 1e-35 121.4 1.6 1.8e-35 120.6 1.1 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination FAD_binding_2 PF00890.19 EMG47790.1 - 1.3e-123 412.9 3.0 1.6e-123 412.6 2.1 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EMG47790.1 - 2.6e-46 156.6 0.7 3.8e-46 156.1 0.5 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.12 EMG47790.1 - 5.1e-07 29.0 0.1 0.00056 19.0 0.0 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 EMG47790.1 - 4.7e-06 25.7 0.4 0.0019 17.1 0.8 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EMG47790.1 - 5.3e-06 25.5 0.1 0.00017 20.5 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMG47790.1 - 2.5e-05 24.2 5.4 0.00018 21.4 0.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMG47790.1 - 0.0069 14.8 0.1 0.18 10.2 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 EMG47790.1 - 0.022 13.7 0.1 0.022 13.7 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 EMG47790.1 - 0.027 13.3 0.3 1.1 8.1 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EMG47790.1 - 0.14 12.2 2.2 1.6 8.7 0.3 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AAA PF00004.24 EMG47791.1 - 2.2e-40 137.9 0.0 3.6e-40 137.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMG47791.1 - 5.2e-06 26.6 0.0 0.00078 19.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EMG47791.1 - 1.6e-05 24.6 0.1 9.2e-05 22.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMG47791.1 - 0.00011 22.2 0.0 0.00034 20.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 EMG47791.1 - 0.00022 21.1 0.0 0.00053 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EMG47791.1 - 0.00051 19.0 0.0 0.00085 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EMG47791.1 - 0.0012 19.6 0.0 0.0026 18.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMG47791.1 - 0.0044 16.0 0.0 0.0078 15.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EMG47791.1 - 0.0054 16.4 0.1 0.01 15.6 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EMG47791.1 - 0.0078 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMG47791.1 - 0.01 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 EMG47791.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EMG47791.1 - 0.019 14.6 0.0 3.9 7.1 0.0 2.4 1 1 1 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 EMG47791.1 - 0.02 15.2 0.0 0.05 13.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 EMG47791.1 - 0.02 14.7 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMG47791.1 - 0.025 14.7 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 EMG47791.1 - 0.026 13.9 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 EMG47791.1 - 0.029 13.9 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EMG47791.1 - 0.031 14.3 0.0 0.071 13.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 EMG47791.1 - 0.032 13.3 0.0 0.079 12.1 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 EMG47791.1 - 0.034 12.8 0.0 0.056 12.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_24 PF13479.1 EMG47791.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EMG47791.1 - 0.11 11.9 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain SF-assemblin PF06705.6 EMG47791.1 - 0.13 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin RNA_pol_Rbc25 PF08292.7 EMG47792.1 - 3.6e-40 136.9 0.9 5.1e-40 136.4 0.6 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EMG47792.1 - 1.7e-14 53.6 0.0 2.6e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Mito_morph_reg PF14972.1 EMG47792.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator rve PF00665.21 EMG47793.1 - 1.2e-17 64.1 0.0 2.9e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EMG47793.1 - 2.7e-07 30.1 0.1 6.6e-07 28.9 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Spt20 PF12090.3 EMG47794.1 - 1.1e-51 174.8 5.4 1.1e-51 174.8 3.7 6.3 2 1 1 3 3 3 1 Spt20 family SecY PF00344.15 EMG47795.1 - 1.6e-68 231.2 23.4 2e-68 230.8 16.2 1.0 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EMG47795.1 - 2.2e-10 39.8 1.4 6.9e-10 38.2 1.0 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p TnpV PF14198.1 EMG47796.1 - 0.14 12.1 1.9 0.43 10.4 0.5 2.2 2 1 0 2 2 2 0 Transposon-encoded protein TnpV SPT6_acidic PF14632.1 EMG47796.1 - 1.1 9.4 19.5 5.5 7.2 0.5 2.6 2 1 0 2 2 2 0 Acidic N-terminal SPT6 DMRL_synthase PF00885.14 EMG47797.1 - 8.5e-48 161.6 0.0 9.6e-48 161.5 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase FHA PF00498.21 EMG47798.1 - 6.9e-08 32.5 0.4 2.5e-07 30.7 0.2 2.1 1 1 1 2 2 2 1 FHA domain Allene_ox_cyc PF06351.6 EMG47798.1 - 0.12 11.7 0.0 0.3 10.5 0.0 1.6 2 0 0 2 2 2 0 Allene oxide cyclase Raptor_N PF14538.1 EMG47799.1 - 4.6e-66 221.4 0.1 1.1e-65 220.1 0.1 1.7 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EMG47799.1 - 8.3e-11 41.3 5.9 0.084 12.7 0.0 7.3 7 0 0 7 7 7 3 WD domain, G-beta repeat HEAT PF02985.17 EMG47799.1 - 0.0097 15.9 0.0 4.1 7.7 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat Mito_carr PF00153.22 EMG47800.1 - 9.6e-64 211.1 0.2 3e-24 84.5 0.2 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein PsaL PF02605.10 EMG47800.1 - 0.0054 16.2 0.1 0.011 15.2 0.1 1.5 1 0 0 1 1 1 1 Photosystem I reaction centre subunit XI Ubiq_cyt_C_chap PF03981.7 EMG47801.1 - 0.081 12.7 0.1 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone ApoO PF09769.4 EMG47802.1 - 6.1e-48 162.5 0.1 6.1e-48 162.5 0.1 2.5 3 0 0 3 3 3 1 Apolipoprotein O LKAAEAR PF15478.1 EMG47802.1 - 0.018 15.3 0.3 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function with LKAAEAR motif THOC7 PF05615.8 EMG47802.1 - 0.021 15.1 2.4 0.23 11.7 0.1 2.0 1 1 1 2 2 2 0 Tho complex subunit 7 HrcA PF01628.16 EMG47802.1 - 0.029 13.9 0.1 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 HrcA protein C terminal domain PPO1_DWL PF12142.3 EMG47802.1 - 0.067 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Polyphenol oxidase middle domain Rsm22 PF09243.5 EMG47803.1 - 2.4e-26 92.3 0.4 7.3e-08 31.7 0.0 4.2 4 0 0 4 4 4 4 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.1 EMG47803.1 - 0.00064 19.4 0.0 0.0022 17.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMG47803.1 - 0.067 13.7 0.0 0.34 11.5 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EMG47803.1 - 0.072 13.5 0.0 0.35 11.3 0.0 2.3 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S27e PF01667.12 EMG47804.1 - 5.2e-26 89.9 2.6 6.7e-26 89.5 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EMG47804.1 - 0.005 16.6 0.7 0.0069 16.2 0.5 1.2 1 0 0 1 1 1 1 IBR domain Mu-like_Com PF10122.4 EMG47804.1 - 0.034 13.2 1.8 0.5 9.4 0.0 2.2 1 1 1 2 2 2 0 Mu-like prophage protein Com zf-HIT PF04438.11 EMG47804.1 - 2.2 8.0 5.2 1.2 8.8 0.4 2.3 3 0 0 3 3 3 0 HIT zinc finger Pkinase PF00069.20 EMG47806.1 - 1.2e-29 103.2 0.0 5e-29 101.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG47806.1 - 2.8e-15 56.0 0.0 1.4e-13 50.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Rif1_N PF12231.3 EMG47807.1 - 2e-27 96.1 13.5 2e-27 96.1 9.4 2.4 2 1 0 2 2 2 1 Rap1-interacting factor 1 N terminal RF-1 PF00472.15 EMG47808.1 - 4.9e-12 45.6 0.3 4.9e-12 45.6 0.2 2.6 2 0 0 2 2 2 1 RF-1 domain Redoxin PF08534.5 EMG47809.1 - 6.4e-32 110.1 0.1 7.7e-32 109.8 0.1 1.0 1 0 0 1 1 1 1 Redoxin DCP1 PF06058.8 EMG47810.1 - 3.9e-17 62.4 0.2 1.1e-10 41.6 0.0 2.8 1 1 2 3 3 3 2 Dcp1-like decapping family Zn_clus PF00172.13 EMG47811.1 - 1.1e-08 34.8 11.6 1.1e-08 34.8 8.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2318 PF10080.4 EMG47811.1 - 0.066 12.9 1.8 0.14 11.9 1.3 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Ras PF00071.17 EMG47812.1 - 4e-42 143.3 0.6 4.9e-42 143.0 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMG47812.1 - 1.3e-14 54.7 0.1 2.6e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMG47812.1 - 3e-14 52.6 0.1 4.1e-14 52.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMG47812.1 - 7e-09 35.1 0.8 1e-08 34.6 0.5 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMG47812.1 - 5.7e-06 25.8 1.0 0.00012 21.6 0.7 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EMG47812.1 - 1.6e-05 24.1 0.1 4.5e-05 22.7 0.0 1.5 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EMG47812.1 - 2.2e-05 24.3 0.0 4.1e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EMG47812.1 - 0.00083 18.8 0.2 0.33 10.4 0.0 2.4 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EMG47812.1 - 0.016 15.0 0.6 0.036 13.8 0.4 1.8 1 1 0 1 1 1 0 Dynamin family Septin PF00735.13 EMG47812.1 - 0.052 12.5 2.9 0.76 8.7 0.0 2.5 2 1 1 3 3 3 0 Septin ATP_bind_1 PF03029.12 EMG47812.1 - 0.056 12.9 1.2 1.4 8.3 0.1 2.6 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EMG47812.1 - 0.072 13.0 0.2 0.11 12.5 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EMG47812.1 - 0.077 13.1 0.1 0.91 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain NTP_transf_2 PF01909.18 EMG47813.1 - 6.3e-15 55.2 0.0 6.3e-15 55.2 0.0 2.6 2 1 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 EMG47813.1 - 1.3e-12 47.4 0.1 3.6e-12 46.0 0.1 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase DUF3754 PF12576.3 EMG47814.1 - 0.071 12.7 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) Glucan_synthase PF02364.10 EMG47815.1 - 0 1230.1 5.0 0 1229.7 3.5 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EMG47815.1 - 5.3e-35 119.8 1.4 1.8e-34 118.1 1.0 2.0 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 SnoaL PF07366.7 EMG47815.1 - 0.24 10.9 0.1 0.46 10.0 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase SSB PF00436.20 EMG47816.1 - 6.2e-20 71.0 0.5 7.6e-20 70.7 0.4 1.1 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.20 EMG47816.1 - 0.026 14.3 0.1 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Peptidase_M28 PF04389.12 EMG47817.1 - 2e-22 79.8 0.0 3.3e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EMG47817.1 - 0.026 14.0 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Nucleoporin_C PF03177.9 EMG47818.1 - 6.7e-122 407.9 22.2 6.7e-122 407.9 15.4 1.8 2 0 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EMG47818.1 - 2e-119 399.1 15.0 2.9e-119 398.5 10.4 1.3 1 0 0 1 1 1 1 Nup133 N terminal like PRK PF00485.13 EMG47819.1 - 9.4e-16 57.9 0.0 1.2e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EMG47819.1 - 0.07 13.4 0.1 0.09 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Spore_II_R PF09551.5 EMG47819.1 - 0.14 12.2 0.0 0.32 11.0 0.0 1.8 1 1 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) DEAD PF00270.24 EMG47820.1 - 4.8e-42 143.3 2.9 6.8e-42 142.8 1.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG47820.1 - 1.8e-28 98.1 0.5 5.3e-28 96.6 0.2 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EMG47820.1 - 0.00058 18.7 1.2 0.0087 14.8 0.1 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain UvsW PF11637.3 EMG47820.1 - 0.0007 19.2 0.1 0.0026 17.4 0.1 2.1 1 0 0 1 1 1 1 ATP-dependant DNA helicase UvsW ResIII PF04851.10 EMG47820.1 - 0.002 17.9 0.2 0.0052 16.6 0.2 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 EMG47820.1 - 0.0065 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Helicase AAA_19 PF13245.1 EMG47820.1 - 0.0066 16.1 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EMG47820.1 - 0.011 15.3 0.3 0.06 12.9 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EMG47820.1 - 0.026 14.7 0.9 0.11 12.6 0.6 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Flavi_DEAD PF07652.9 EMG47820.1 - 0.13 12.0 0.5 0.47 10.1 0.0 2.3 2 1 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.1 EMG47820.1 - 0.15 12.2 1.8 1.1 9.4 1.3 2.3 1 1 0 1 1 1 0 AAA domain HEAT_EZ PF13513.1 EMG47821.1 - 5.1e-16 58.6 4.4 5.2e-05 23.6 0.1 8.6 7 2 3 10 10 10 4 HEAT-like repeat HEAT PF02985.17 EMG47821.1 - 8.6e-11 40.9 6.4 0.0042 17.0 0.0 7.8 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.1 EMG47821.1 - 1.3e-09 38.1 6.4 0.0066 16.7 0.0 7.3 5 2 3 8 8 8 2 HEAT repeats Vac14_Fab1_bd PF12755.2 EMG47821.1 - 3.8e-06 27.1 4.7 6 7.3 0.1 6.5 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 EMG47821.1 - 1.9e-05 24.4 0.6 0.00039 20.2 0.1 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain ParcG PF10274.4 EMG47821.1 - 0.00037 20.4 0.6 2.5 7.9 0.2 3.8 2 2 1 3 3 3 1 Parkin co-regulated protein UME PF08064.8 EMG47821.1 - 0.00046 20.1 5.0 1.2 9.1 0.0 6.0 6 2 2 8 8 8 1 UME (NUC010) domain CLASP_N PF12348.3 EMG47821.1 - 0.001 18.4 0.9 0.34 10.2 0.0 4.5 6 0 0 6 6 6 1 CLASP N terminal Cnd1 PF12717.2 EMG47821.1 - 0.0013 18.6 4.2 3.9 7.3 0.0 5.6 5 3 2 7 7 7 1 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.1 EMG47821.1 - 0.0083 16.0 0.6 14 5.7 0.0 4.3 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 STE3 PF02076.10 EMG47822.1 - 3.1e-88 295.5 22.0 3.8e-88 295.2 15.3 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF912 PF06024.7 EMG47822.1 - 1.2 9.1 7.8 9.7 6.3 0.3 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) GatB_N PF02934.10 EMG47823.1 - 4.6e-99 330.9 0.0 6.9e-99 330.3 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EMG47823.1 - 1.2e-26 93.1 0.3 2e-26 92.4 0.2 1.3 1 0 0 1 1 1 1 GatB domain NPL4 PF05021.10 EMG47824.1 - 2.8e-122 407.7 0.0 3.7e-122 407.2 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EMG47824.1 - 2.4e-66 221.9 0.4 6.1e-66 220.6 0.1 1.8 2 0 0 2 2 2 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EMG47824.1 - 2.3e-06 27.8 0.1 5.9e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 HSP70 PF00012.15 EMG47826.1 - 6.8e-166 552.7 5.2 6.8e-166 552.7 3.6 2.1 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EMG47826.1 - 7.6e-12 44.4 0.0 1.9e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 EMG47826.1 - 0.019 14.8 2.7 0.29 10.9 0.4 3.2 2 2 0 2 2 2 0 Cell division protein FtsA NLE PF08154.7 EMG47826.1 - 0.04 13.9 0.4 0.19 11.7 0.1 2.3 2 0 0 2 2 2 0 NLE (NUC135) domain Pkinase PF00069.20 EMG47827.1 - 5.4e-47 160.1 4.3 2.1e-26 92.6 1.8 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMG47827.1 - 3e-18 65.8 1.1 5.8e-14 51.7 0.3 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase P34-Arc PF04045.9 EMG47828.1 - 3.5e-105 350.6 1.6 4.2e-105 350.3 1.1 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 EMG47828.1 - 0.049 13.0 0.5 0.11 11.8 0.4 1.5 1 1 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) Ribosom_S12_S23 PF00164.20 EMG47829.1 - 4.5e-46 155.2 2.6 6e-46 154.8 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 PP-binding PF00550.20 EMG47830.1 - 4.9e-12 45.9 0.5 6.9e-12 45.4 0.3 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EMG47830.1 - 4.9e-05 23.2 0.2 6.8e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EMG47830.1 - 0.015 15.4 0.1 0.023 14.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) QCR10 PF09796.4 EMG47831.1 - 2.8e-25 87.7 0.8 3.2e-25 87.5 0.6 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 EMG47831.1 - 2.5e-05 23.8 0.4 4.1e-05 23.2 0.2 1.5 1 1 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Cullin PF00888.17 EMG47832.1 - 1.3e-44 152.7 37.7 1.3e-44 152.7 26.1 1.6 1 1 1 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 EMG47832.1 - 5.8e-14 51.6 4.3 2e-13 49.9 3.0 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain FrhB_FdhB_C PF04432.8 EMG47832.1 - 0.046 13.1 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus Rrf2 PF02082.15 EMG47832.1 - 0.076 13.1 0.0 0.49 10.5 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator COMPASS-Shg1 PF05205.7 EMG47833.1 - 0.00071 19.8 0.8 0.00071 19.8 0.5 2.1 2 1 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 DUF2796 PF10986.3 EMG47833.1 - 0.0067 16.4 14.3 0.0075 16.2 9.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2796) BAF1_ABF1 PF04684.8 EMG47833.1 - 0.047 12.5 17.7 0.05 12.4 12.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Macoilin PF09726.4 EMG47833.1 - 0.17 10.1 13.1 0.2 9.9 9.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Zip PF02535.17 EMG47833.1 - 0.34 9.8 11.5 0.35 9.8 8.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter ApbA PF02558.11 EMG47834.1 - 2.8e-26 91.7 0.0 3.9e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EMG47834.1 - 3.7e-24 85.1 0.0 5.3e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Pyr_redox PF00070.22 EMG47834.1 - 0.03 14.7 0.0 0.062 13.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMG47834.1 - 0.073 11.9 0.1 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ThiF PF00899.16 EMG47834.1 - 0.082 12.7 0.2 0.45 10.3 0.0 2.2 3 0 0 3 3 3 0 ThiF family FAD_binding_3 PF01494.14 EMG47834.1 - 0.18 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Phos_pyr_kin PF08543.7 EMG47835.1 - 2.7e-13 49.7 0.0 3.5e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EMG47835.1 - 1.7e-08 33.9 0.0 3.2e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase bZIP_2 PF07716.10 EMG47836.1 - 7.8e-06 25.6 12.9 8.6e-06 25.4 7.6 2.1 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EMG47836.1 - 5.3e-05 23.1 6.8 0.00015 21.6 4.7 1.8 1 0 0 1 1 1 1 bZIP transcription factor Gag_p17 PF00540.13 EMG47836.1 - 0.015 15.0 1.2 0.015 15.0 0.8 2.0 2 0 0 2 2 2 0 gag gene protein p17 (matrix protein) TMCO5 PF14992.1 EMG47836.1 - 0.25 10.4 25.1 0.061 12.4 11.1 2.1 1 1 1 2 2 2 0 TMCO5 family Med24_N PF11277.3 EMG47836.1 - 0.51 7.7 6.4 1 6.7 4.4 1.5 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal Pirin PF02678.11 EMG47837.1 - 5.1e-28 97.0 0.0 9.8e-28 96.1 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EMG47837.1 - 4.2e-15 55.6 0.4 1e-14 54.4 0.1 1.7 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EMG47837.1 - 0.03 13.8 0.1 0.075 12.5 0.1 1.6 1 0 0 1 1 1 0 Cupin domain ABC_trans_N PF14510.1 EMG47839.1 - 2.6e-12 46.6 0.6 6.6e-12 45.3 0.0 2.0 2 1 0 2 2 2 1 ABC-transporter extracellular N-terminal ABC_tran PF00005.22 EMG47839.1 - 4.1e-05 23.8 1.2 0.0001 22.6 0.0 2.2 2 1 0 2 2 2 1 ABC transporter Pirin PF02678.11 EMG47840.1 - 1.6e-26 92.2 0.1 2.2e-26 91.8 0.1 1.2 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.6 EMG47840.1 - 0.00053 19.4 0.2 0.00087 18.7 0.2 1.4 1 0 0 1 1 1 1 Cupin domain UPF0370 PF13980.1 EMG47841.1 - 1.2 8.9 6.0 36 4.2 0.0 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0370) FYVE_2 PF02318.11 EMG47841.1 - 4.2 7.3 8.9 0.4 10.5 2.6 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger DUF4603 PF15376.1 EMG47842.1 - 0.015 12.5 0.5 0.019 12.1 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF1796 PF08795.5 EMG47842.1 - 0.044 13.4 0.3 0.078 12.6 0.2 1.4 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Peptidase_M20 PF01546.23 EMG47843.1 - 2.5e-22 79.3 0.0 4.5e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EMG47843.1 - 2.1e-13 49.5 7.1 0.0036 17.1 0.2 5.9 7 0 0 7 7 7 4 WD domain, G-beta repeat M20_dimer PF07687.9 EMG47843.1 - 1.5e-10 40.7 0.0 4.4e-10 39.2 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EMG47843.1 - 0.00048 19.9 0.0 0.15 11.7 0.0 2.6 2 0 0 2 2 2 2 Peptidase family M28 SPX PF03105.14 EMG47844.1 - 2e-45 155.7 26.7 8.9e-44 150.3 18.5 2.3 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EMG47844.1 - 2.4e-24 86.0 44.6 3.2e-24 85.6 30.9 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EMG47844.1 - 2e-09 36.4 50.9 4.5e-08 32.0 18.8 2.4 1 1 1 2 2 2 2 Citrate transporter ASFV_J13L PF05568.6 EMG47844.1 - 0.09 12.3 0.7 1.1 8.7 0.2 2.4 2 0 0 2 2 2 0 African swine fever virus J13L protein SRP54_N PF02881.14 EMG47845.1 - 0.036 14.1 0.0 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain Pirin PF02678.11 EMG47847.1 - 2.3e-25 88.5 0.0 5.6e-25 87.2 0.0 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EMG47847.1 - 2.5e-17 62.8 0.1 4.9e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Pirin PF02678.11 EMG47848.1 - 1.1e-29 102.4 0.0 2.3e-29 101.3 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EMG47848.1 - 5.6e-18 64.9 0.1 1.7e-17 63.4 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EMG47848.1 - 0.017 14.6 0.1 0.043 13.3 0.1 1.6 1 0 0 1 1 1 0 Cupin domain Smg4_UPF3 PF03467.10 EMG47849.1 - 0.12 12.3 0.8 0.19 11.7 0.6 1.2 1 0 0 1 1 1 0 Smg-4/UPF3 family Peptidase_M50 PF02163.17 EMG47850.1 - 0.0061 15.5 0.0 0.0075 15.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M50 YebO PF13974.1 EMG47850.1 - 0.037 13.8 0.3 0.98 9.2 0.0 3.4 2 1 0 2 2 2 0 YebO-like protein Pirin PF02678.11 EMG47851.1 - 1.9e-28 98.4 0.2 3.2e-28 97.7 0.2 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EMG47851.1 - 6.9e-17 61.4 0.1 2.5e-15 56.4 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EMG47851.1 - 0.00019 20.8 3.4 0.0022 17.4 0.2 2.3 2 0 0 2 2 2 2 Cupin domain Peptidase_S10 PF00450.17 EMG47853.1 - 8.8e-129 430.2 0.1 1.2e-128 429.8 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EMG47853.1 - 7.1e-05 22.7 0.0 0.00029 20.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family COX14 PF14880.1 EMG47855.1 - 4.3e-13 48.6 0.0 5.2e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Rtf2 PF04641.7 EMG47856.1 - 2.9e-36 125.0 5.1 3.5e-36 124.7 3.5 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 EMG47856.1 - 8.4e-06 25.4 0.3 2.3e-05 24.0 0.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Rad10 PF03834.9 EMG47857.1 - 1.9e-24 85.1 0.5 1.7e-23 82.0 0.1 2.2 1 1 1 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EMG47857.1 - 0.0014 18.7 0.0 0.0033 17.5 0.0 1.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain DUF2893 PF11459.3 EMG47857.1 - 0.13 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknwon function (DUF2893) Methyltransf_11 PF08241.7 EMG47858.1 - 2.7e-17 63.0 0.0 5.6e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMG47858.1 - 1.4e-10 40.9 0.0 2.4e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMG47858.1 - 2.2e-10 40.7 0.0 4.1e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMG47858.1 - 4.4e-10 40.1 0.0 8.1e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMG47858.1 - 5.8e-10 39.5 0.0 1.2e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMG47858.1 - 1.3e-08 34.7 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMG47858.1 - 8.7e-05 22.5 0.0 0.00022 21.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EMG47858.1 - 9.1e-05 22.1 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMG47858.1 - 0.00018 20.6 0.0 0.0003 19.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EMG47858.1 - 0.0011 18.3 0.0 0.0033 16.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 EMG47858.1 - 0.0057 15.4 0.0 0.0098 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_PK PF05891.7 EMG47858.1 - 0.0063 15.8 0.1 0.016 14.5 0.0 1.5 2 0 0 2 2 2 1 AdoMet dependent proline di-methyltransferase DREV PF05219.7 EMG47858.1 - 0.0086 14.9 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_4 PF02390.12 EMG47858.1 - 0.024 13.6 0.0 0.21 10.5 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase NodS PF05401.6 EMG47858.1 - 0.029 13.7 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_8 PF05148.10 EMG47858.1 - 0.11 12.0 0.0 1.5 8.3 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase Pirin PF02678.11 EMG47859.1 - 1.4e-29 102.1 0.0 2.7e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EMG47859.1 - 4.7e-19 68.3 0.2 1.3e-18 67.0 0.1 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EMG47859.1 - 0.0016 17.8 0.6 0.02 14.3 0.2 2.3 2 0 0 2 2 2 1 Cupin domain Atg8 PF02991.11 EMG47860.1 - 1.1e-47 160.2 0.1 1.4e-47 159.9 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EMG47860.1 - 3.6e-07 30.2 0.0 5.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 AA_permease_2 PF13520.1 EMG47861.1 - 3.3e-48 164.3 56.9 3.9e-48 164.0 39.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMG47861.1 - 3.8e-07 28.8 52.0 5.1e-07 28.4 36.0 1.1 1 0 0 1 1 1 1 Amino acid permease Ribosomal_L30_N PF08079.7 EMG47862.1 - 2.2e-19 69.2 21.1 4.1e-19 68.3 14.6 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EMG47862.1 - 5.1e-19 67.5 0.9 1.2e-18 66.4 0.6 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e KLRAQ PF10205.4 EMG47863.1 - 0.00072 19.5 13.0 0.00072 19.5 9.0 2.4 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein DUF4407 PF14362.1 EMG47863.1 - 0.001 18.1 1.3 0.0015 17.5 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DivIC PF04977.10 EMG47863.1 - 0.0029 17.0 2.3 0.0029 17.0 1.6 3.9 2 1 2 4 4 4 1 Septum formation initiator YjcZ PF13990.1 EMG47863.1 - 0.049 12.7 9.6 0.36 9.9 0.2 2.2 1 1 1 2 2 2 0 YjcZ-like protein Reo_sigmaC PF04582.7 EMG47863.1 - 0.12 11.4 0.7 0.22 10.6 0.5 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein COG5 PF10392.4 EMG47863.1 - 0.15 12.0 14.3 0.46 10.4 2.5 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 AAA_13 PF13166.1 EMG47863.1 - 0.45 8.9 19.3 0.64 8.4 13.4 1.2 1 0 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.3 EMG47863.1 - 1.5 8.7 30.0 31 4.4 9.2 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 EMG47863.1 - 2.2 8.1 26.4 0.87 9.4 3.4 2.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding FliD_N PF02465.13 EMG47863.1 - 2.6 8.4 10.5 10 6.5 2.0 2.9 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus ERM PF00769.14 EMG47863.1 - 2.9 7.3 21.1 15 5.0 14.7 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF972 PF06156.8 EMG47863.1 - 4 7.8 16.2 0.32 11.3 3.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF641 PF04859.7 EMG47863.1 - 4.6 7.0 15.7 6.5 6.5 4.6 2.6 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Fib_alpha PF08702.5 EMG47863.1 - 6.5 6.8 20.1 2 8.5 2.7 2.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family PLU-1 PF08429.6 EMG47864.1 - 3e-65 220.3 13.6 4.5e-63 213.1 5.1 2.6 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 EMG47864.1 - 1e-20 74.0 0.9 1.9e-10 40.9 0.1 3.1 2 0 0 2 2 2 2 JmjC domain, hydroxylase ARID PF01388.16 EMG47864.1 - 1.2e-19 69.9 0.0 7.6e-19 67.3 0.0 2.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 EMG47864.1 - 6.9e-09 35.2 10.2 1.6e-08 34.0 7.1 1.7 1 0 0 1 1 1 1 PHD-finger JmjN PF02375.12 EMG47864.1 - 0.0021 17.5 0.1 0.0085 15.5 0.0 2.1 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.1 EMG47864.1 - 0.0073 16.4 0.4 0.021 14.9 0.3 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EMG47864.1 - 0.0091 15.9 0.4 0.027 14.4 0.3 1.8 1 0 0 1 1 1 1 PHD-zinc-finger like domain C1_1 PF00130.17 EMG47864.1 - 0.033 13.9 3.0 0.063 13.0 2.1 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.1 EMG47864.1 - 0.33 10.8 6.9 0.64 9.8 4.8 1.5 1 0 0 1 1 1 0 Ring finger domain PHD_2 PF13831.1 EMG47864.1 - 1 8.7 5.7 2.5 7.4 4.0 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 EMG47864.1 - 5.4 7.1 6.9 10 6.2 4.8 1.4 1 0 0 1 1 1 0 RING-like domain Flocculin_t3 PF13928.1 EMG47865.1 - 3.7e-05 23.7 21.1 0.012 15.7 6.0 2.3 2 0 0 2 2 2 2 Flocculin type 3 repeat IDO PF01231.13 EMG47866.1 - 2.7e-164 546.6 0.0 3e-164 546.4 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Imm42 PF15601.1 EMG47866.1 - 0.05 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 42 Herpes_pp85 PF04637.7 EMG47866.1 - 0.054 11.7 0.0 0.077 11.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) tRNA-synt_His PF13393.1 EMG47867.1 - 3.6e-39 134.6 0.1 2.4e-32 112.2 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EMG47867.1 - 5e-18 65.2 0.0 1.1e-17 64.2 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMG47867.1 - 1.1e-10 41.3 0.0 2.4e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EMG47867.1 - 3.2e-05 22.8 0.0 0.00095 18.0 0.0 2.5 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.2 EMG47867.1 - 0.012 14.7 0.1 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs tRNA-synt_2d PF01409.15 EMG47867.1 - 0.062 12.4 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) FA_desaturase PF00487.19 EMG47868.1 - 2.6e-31 109.0 10.2 3.8e-31 108.4 7.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EMG47868.1 - 8.7e-19 66.4 0.3 1.7e-18 65.5 0.2 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) EST1_DNA_bind PF10373.4 EMG47869.1 - 2.1e-35 122.3 4.8 2.1e-35 122.3 3.3 1.8 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EMG47869.1 - 4e-24 85.0 1.9 4e-24 85.0 1.3 3.0 3 1 0 3 3 3 1 Telomerase activating protein Est1 TPR_11 PF13414.1 EMG47869.1 - 0.063 12.9 0.1 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 TPR repeat Peptidase_C97 PF05903.9 EMG47870.1 - 4.7e-32 110.8 2.5 5.2e-32 110.7 0.8 1.8 2 0 0 2 2 2 1 PPPDE putative peptidase domain Tra_M PF05261.6 EMG47870.1 - 0.057 13.4 1.9 0.072 13.1 0.1 2.1 2 0 0 2 2 2 0 TraM protein, DNA-binding LRAT PF04970.8 EMG47870.1 - 0.065 13.1 0.9 0.22 11.4 0.6 1.9 1 0 0 1 1 1 0 Lecithin retinol acyltransferase PH PF00169.24 EMG47871.1 - 4.8e-10 39.5 1.9 4.8e-10 39.5 1.3 2.8 3 1 0 3 3 3 1 PH domain PH_11 PF15413.1 EMG47871.1 - 0.0023 18.1 0.8 0.0023 18.1 0.6 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain ILVD_EDD PF00920.16 EMG47872.1 - 2.1e-204 679.7 0.0 2.4e-204 679.5 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Adap_comp_sub PF00928.16 EMG47873.1 - 1.4e-87 293.1 0.2 1.7e-87 292.8 0.2 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EMG47873.1 - 1.3e-09 37.9 1.6 2.4e-09 37.0 1.1 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Flocculin_t3 PF13928.1 EMG47874.1 - 0.033 14.3 21.5 0.033 14.3 14.9 5.8 2 2 1 3 3 3 0 Flocculin type 3 repeat DUF4196 PF13846.1 EMG47874.1 - 1 9.6 3.9 1.7 8.9 1.8 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4196) Pput2613-deam PF14427.1 EMG47874.1 - 4.8 6.8 6.0 5.5 6.6 0.5 2.7 1 1 3 4 4 4 0 Pput_2613-like deaminase Cellulase PF00150.13 EMG47875.1 - 1.7e-16 60.2 0.6 1.5e-08 34.1 0.1 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) OB_NTP_bind PF07717.11 EMG47876.1 - 5.1e-28 97.1 0.1 1.4e-27 95.7 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EMG47876.1 - 2.3e-27 95.0 0.1 2.3e-27 95.0 0.0 3.0 2 1 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EMG47876.1 - 1.3e-12 47.3 0.0 3.6e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 EMG47876.1 - 2.3e-12 46.8 0.0 5.3e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 EMG47876.1 - 1.5e-06 27.8 0.2 3.1e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EMG47876.1 - 2.3e-05 24.5 0.0 0.00016 21.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EMG47876.1 - 0.0011 19.2 8.0 0.052 13.8 0.1 3.9 2 2 0 2 2 2 1 ABC transporter AAA_14 PF13173.1 EMG47876.1 - 0.0019 18.0 0.6 0.044 13.6 0.2 3.0 2 1 0 2 2 2 1 AAA domain ResIII PF04851.10 EMG47876.1 - 0.0067 16.2 1.0 0.37 10.6 0.0 3.1 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EMG47876.1 - 0.01 14.7 0.0 0.024 13.5 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Miro PF08477.8 EMG47876.1 - 0.011 16.2 0.3 0.047 14.1 0.2 2.2 1 1 0 1 1 1 0 Miro-like protein NB-ARC PF00931.17 EMG47876.1 - 0.012 14.4 0.0 0.041 12.7 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.1 EMG47876.1 - 0.017 14.7 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EMG47876.1 - 0.019 14.0 0.0 0.049 12.7 0.0 1.7 1 0 0 1 1 1 0 KaiC SRP54 PF00448.17 EMG47876.1 - 0.024 14.0 0.3 0.058 12.8 0.2 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 EMG47876.1 - 0.044 13.5 0.1 0.097 12.4 0.1 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain PhoH PF02562.11 EMG47876.1 - 0.044 13.0 0.1 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.1 EMG47876.1 - 0.047 13.4 0.2 0.13 12.0 0.1 1.8 2 0 0 2 2 1 0 Part of AAA domain PCI PF01399.22 EMG47877.1 - 2e-15 56.9 2.2 2e-15 56.9 1.5 2.4 3 0 0 3 3 3 1 PCI domain DUF2132 PF09905.4 EMG47877.1 - 0.05 13.5 0.1 0.22 11.4 0.0 2.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2132) Glyco_hydro_72 PF03198.9 EMG47878.1 - 1.6e-133 444.5 3.8 2e-133 444.2 2.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 EMG47878.1 - 0.0012 17.8 0.2 0.0047 15.8 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain PFK PF00365.15 EMG47879.1 - 8.4e-171 566.3 2.3 7.5e-123 408.9 0.8 2.1 2 0 0 2 2 2 2 Phosphofructokinase TMCO5 PF14992.1 EMG47879.1 - 0.036 13.1 2.2 0.074 12.1 1.5 1.4 1 0 0 1 1 1 0 TMCO5 family SPRY PF00622.23 EMG47880.1 - 1.6e-05 25.0 0.0 4.7e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 SPRY domain SMC_Nse1 PF07574.8 EMG47881.1 - 4e-26 91.8 1.5 2.3e-24 86.1 1.0 2.1 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EMG47881.1 - 0.00056 19.8 0.3 0.0011 18.9 0.2 1.4 1 0 0 1 1 1 1 RING-like domain Dynamin_M PF01031.15 EMG47881.1 - 0.019 13.7 0.6 0.16 10.6 0.3 2.0 1 1 1 2 2 2 0 Dynamin central region PHD PF00628.24 EMG47881.1 - 0.16 11.6 1.1 5.4 6.7 0.0 2.3 2 0 0 2 2 2 0 PHD-finger Glyco_hydro_16 PF00722.16 EMG47882.1 - 4.2e-43 146.7 0.9 6e-43 146.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Sugar_tr PF00083.19 EMG47883.1 - 3.1e-60 204.0 15.0 3.5e-60 203.8 10.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Alpha-amylase PF00128.19 EMG47884.1 - 2.1e-103 346.0 3.7 2.1e-103 346.0 2.5 1.8 2 0 0 2 2 2 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 EMG47884.1 - 7.2e-05 21.8 0.1 0.00055 18.9 0.0 2.2 2 0 0 2 2 2 1 glucanotransferase domain of human glycogen debranching enzyme Sugar_tr PF00083.19 EMG47885.1 - 8.3e-80 268.5 25.4 1.1e-79 268.1 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG47885.1 - 6.4e-19 67.8 23.3 2.7e-18 65.8 12.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMG47885.1 - 0.00013 20.4 23.0 0.0003 19.3 3.9 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein DUF4231 PF14015.1 EMG47885.1 - 5.8 6.9 6.1 1.6 8.7 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) ADH_zinc_N PF00107.21 EMG47886.1 - 2.8e-32 111.0 1.3 4.7e-32 110.2 0.9 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMG47886.1 - 1.7e-29 101.7 0.5 3.1e-29 100.9 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EMG47886.1 - 0.00015 22.6 0.1 0.00031 21.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase F-box-like PF12937.2 EMG47888.1 - 0.011 15.4 0.4 0.045 13.4 0.3 2.0 1 0 0 1 1 1 0 F-box-like Alpha-amylase PF00128.19 EMG47889.1 - 4.7e-103 344.9 2.5 4.7e-103 344.9 1.7 2.2 2 1 0 2 2 2 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 EMG47889.1 - 0.00014 20.8 0.1 0.00036 19.5 0.0 1.6 2 0 0 2 2 2 1 glucanotransferase domain of human glycogen debranching enzyme Sugar_tr PF00083.19 EMG47890.1 - 1.5e-06 27.1 1.0 1.5e-06 27.1 0.7 1.4 2 0 0 2 2 2 1 Sugar (and other) transporter DUF915 PF06028.6 EMG47890.1 - 0.041 12.9 0.1 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) MFS_1 PF07690.11 EMG47890.1 - 0.07 11.8 3.5 0.11 11.1 2.4 1.3 1 0 0 1 1 1 0 Major Facilitator Superfamily Glyco_transf_22 PF03901.12 EMG47891.1 - 4.8e-06 25.8 0.0 6e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Nucleos_tra2_N PF01773.15 EMG47891.1 - 0.095 13.0 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter N-terminus Peptidase_C2 PF00648.16 EMG47892.1 - 1.8e-08 33.7 0.0 3.2e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EMG47892.1 - 1.9e-08 34.0 11.5 2.6e-08 33.6 0.8 3.2 3 1 0 3 3 3 2 Calpain large subunit, domain III PLDc_3 PF13918.1 EMG47892.1 - 0.055 12.8 0.3 2 7.8 0.0 3.0 3 0 0 3 3 3 0 PLD-like domain OST3_OST6 PF04756.8 EMG47893.1 - 1.3e-22 80.1 9.3 3.5e-22 78.6 6.4 1.7 1 0 0 1 1 1 1 OST3 / OST6 family ORMDL PF04061.9 EMG47893.1 - 0.00029 20.4 3.2 0.00052 19.5 2.2 1.4 1 0 0 1 1 1 1 ORMDL family Thioredoxin PF00085.15 EMG47893.1 - 0.044 13.4 0.0 4.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin DUF1129 PF06570.6 EMG47893.1 - 0.59 9.4 10.3 0.62 9.3 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF676 PF05057.9 EMG47894.1 - 2e-52 177.6 0.0 3.4e-52 176.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EMG47894.1 - 0.00024 20.7 0.0 0.0005 19.6 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EMG47894.1 - 0.00077 19.1 0.0 0.0022 17.6 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.10 EMG47894.1 - 0.0022 17.0 0.5 0.006 15.6 0.0 1.8 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 EMG47894.1 - 0.0057 16.4 0.0 0.013 15.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family RNA_pol_Rpb4 PF03874.11 EMG47895.1 - 3.4e-26 91.5 1.1 4.6e-26 91.1 0.8 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 NOSIC PF08060.8 EMG47895.1 - 0.072 12.9 0.2 0.21 11.4 0.1 1.8 1 0 0 1 1 1 0 NOSIC (NUC001) domain Eaf7 PF07904.8 EMG47895.1 - 0.88 9.5 5.7 0.5 10.3 0.5 2.3 1 1 0 2 2 2 0 Chromatin modification-related protein EAF7 Fungal_trans PF04082.13 EMG47897.1 - 1.9e-32 112.1 16.1 2.9e-30 105.0 1.1 3.5 4 0 0 4 4 4 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG47897.1 - 3.8e-10 39.5 10.5 8.3e-10 38.4 7.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3912 PF13051.1 EMG47899.1 - 2.4 7.9 5.6 5 6.9 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3912) KH_3 PF13014.1 EMG47900.1 - 0.43 10.2 4.9 18 5.0 0.0 4.3 4 1 0 4 4 4 0 KH domain ATG16 PF08614.6 EMG47901.1 - 6.2e-21 75.1 21.6 6.9e-21 74.9 14.9 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Tetrabrachion PF11401.3 EMG47901.1 - 0.021 14.6 2.8 0.025 14.3 0.5 2.2 2 0 0 2 2 2 0 Tetrabrachion AAA_13 PF13166.1 EMG47901.1 - 0.066 11.6 22.5 0.068 11.6 15.6 1.0 1 0 0 1 1 1 0 AAA domain DUF4446 PF14584.1 EMG47901.1 - 0.25 11.1 5.2 0.5 10.1 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Reo_sigmaC PF04582.7 EMG47901.1 - 2.7 7.0 6.5 3.2 6.8 4.5 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein EF-hand_1 PF00036.27 EMG47902.1 - 1.4e-28 96.0 18.3 7.7e-08 31.1 0.8 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EMG47902.1 - 7.5e-24 83.6 7.0 4.5e-12 45.9 0.8 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMG47902.1 - 9.2e-24 81.1 10.9 8.2e-06 25.2 0.0 4.5 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EMG47902.1 - 1.8e-20 71.3 19.6 7.1e-06 25.1 0.7 4.7 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EMG47902.1 - 7.3e-14 51.1 20.5 4.1e-05 23.1 0.8 4.6 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMG47902.1 - 7.1e-07 29.2 0.0 0.011 15.7 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EMG47902.1 - 8.2e-07 28.7 8.6 0.13 12.0 0.2 3.7 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SET PF00856.23 EMG47903.1 - 1.8e-11 44.6 0.1 4.4e-11 43.3 0.0 1.7 2 0 0 2 2 2 1 SET domain CoaE PF01121.15 EMG47904.1 - 4.1e-43 146.8 0.0 4.8e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EMG47904.1 - 9.7e-08 32.8 0.0 1.2e-07 32.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMG47904.1 - 0.00066 19.5 0.0 0.0016 18.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMG47904.1 - 0.00078 19.7 0.0 0.0011 19.3 0.0 1.3 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 EMG47904.1 - 0.032 14.1 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase-like family SKI PF01202.17 EMG47904.1 - 0.04 13.7 0.0 0.061 13.1 0.0 1.4 1 1 0 1 1 1 0 Shikimate kinase AAA_28 PF13521.1 EMG47904.1 - 0.047 13.6 0.0 0.06 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Corona_6B_7B PF03262.8 EMG47904.1 - 0.097 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Coronavirus 6B/7B protein AAA_14 PF13173.1 EMG47904.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain PRK PF00485.13 EMG47904.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family tRNA_lig_kinase PF08303.6 EMG47904.1 - 0.1 12.4 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 tRNA ligase kinase domain Cpn60_TCP1 PF00118.19 EMG47905.1 - 1.2e-160 535.3 4.0 1.3e-160 535.1 2.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RINT1_TIP1 PF04437.8 EMG47906.1 - 3e-55 187.6 18.8 5e-55 186.9 13.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Pkinase PF00069.20 EMG47907.1 - 7.4e-70 235.0 0.0 1.2e-69 234.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG47907.1 - 1.1e-35 123.0 0.0 1.4e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EMG47907.1 - 8.1e-13 48.3 0.3 2e-12 47.0 0.2 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EMG47907.1 - 0.00034 19.6 0.3 3.9 6.3 0.0 3.2 2 1 1 3 3 3 3 Kinase-like TPR_11 PF13414.1 EMG47908.1 - 3.3e-07 29.8 0.1 1.9e-05 24.2 0.1 2.1 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EMG47908.1 - 0.0059 16.4 3.1 0.59 10.1 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMG47908.1 - 0.071 12.9 3.6 5.4 7.0 0.2 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat PsbU PF06514.6 EMG47908.1 - 0.092 12.6 0.2 7.2 6.5 0.0 2.9 3 0 0 3 3 3 0 Photosystem II 12 kDa extrinsic protein (PsbU) TPR_12 PF13424.1 EMG47908.1 - 0.13 12.2 0.1 1.4 8.8 0.0 2.7 1 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMG47908.1 - 0.57 9.8 4.3 25 4.6 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.7 EMG47908.1 - 1.9 9.2 7.1 2.4 8.9 0.2 3.6 4 0 0 4 4 4 0 Sel1 repeat Homeobox PF00046.24 EMG47909.1 - 3.4e-15 55.4 3.0 9.4e-15 53.9 2.1 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMG47909.1 - 0.043 13.5 0.3 0.043 13.5 0.2 2.0 2 0 0 2 2 2 0 Homeobox KN domain GTP_EFTU PF00009.22 EMG47911.1 - 0.00011 21.7 0.0 0.00013 21.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Peptidase_M16_C PF05193.16 EMG47912.1 - 3.8e-17 62.5 0.2 7.5e-17 61.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EMG47912.1 - 7.5e-08 32.2 0.4 1.4e-05 24.8 0.1 2.7 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) G-alpha PF00503.15 EMG47913.1 - 3.9e-116 387.9 6.4 4.3e-116 387.8 4.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EMG47913.1 - 3.4e-15 55.7 1.8 8.4e-11 41.4 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMG47913.1 - 5.2e-06 25.7 3.9 6.2e-05 22.2 0.1 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EMG47913.1 - 0.003 18.0 1.5 2.8 8.4 0.0 3.1 3 1 0 3 3 3 2 Miro-like protein MMR_HSR1 PF01926.18 EMG47913.1 - 0.016 15.1 0.0 3.8 7.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ras PF00071.17 EMG47913.1 - 0.024 14.0 0.2 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Ras family AAA_29 PF13555.1 EMG47913.1 - 0.079 12.4 0.2 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EMG47913.1 - 0.083 12.3 1.5 1.5 8.1 0.0 2.8 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain Metallophos PF00149.23 EMG47914.1 - 6.9e-15 54.9 1.3 1.2e-14 54.1 0.4 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Cyclin PF08613.6 EMG47916.1 - 9.8e-09 35.7 1.9 1.3e-08 35.3 1.3 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EMG47916.1 - 1.4e-06 27.8 1.4 6.6e-06 25.7 0.9 2.1 1 1 0 1 1 1 1 Cyclin, N-terminal domain IL15 PF02372.10 EMG47916.1 - 0.039 13.7 5.8 1.8 8.3 0.9 2.4 1 1 1 2 2 2 0 Interleukin 15 SR-25 PF10500.4 EMG47916.1 - 0.83 9.0 3.4 1.2 8.5 2.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CybS PF05328.7 EMG47918.1 - 1.6e-56 189.5 0.3 1.9e-56 189.3 0.2 1.0 1 0 0 1 1 1 1 CybS DUF3859 PF12975.2 EMG47919.1 - 0.099 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3859) PPP4R2 PF09184.6 EMG47920.1 - 0.00081 19.0 0.0 0.00081 19.0 0.0 1.1 1 0 0 1 1 1 1 PPP4R2 Ribosomal_S7 PF00177.16 EMG47921.1 - 4e-35 120.5 1.6 6.5e-35 119.8 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e ArdA PF07275.6 EMG47921.1 - 0.081 13.1 0.5 0.2 11.9 0.1 1.7 2 0 0 2 2 2 0 Antirestriction protein (ArdA) DUF4596 PF15363.1 EMG47922.1 - 0.039 13.8 0.1 0.11 12.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) HisG PF01634.13 EMG47923.1 - 3e-54 183.0 0.0 4.4e-54 182.4 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EMG47923.1 - 7.7e-28 96.2 0.1 1.3e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain Proteasome PF00227.21 EMG47924.1 - 2e-38 131.5 0.1 2.4e-38 131.3 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Lum_binding PF00677.12 EMG47925.1 - 1.9e-41 139.8 6.7 1.8e-20 72.5 0.1 2.3 2 0 0 2 2 2 2 Lumazine binding domain Spore_GerAC PF05504.6 EMG47925.1 - 0.028 14.2 2.7 0.036 13.8 1.9 1.3 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Ribosomal_S14 PF00253.16 EMG47926.1 - 1.7e-19 68.9 0.0 4.2e-19 67.6 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e GPCR_chapero_1 PF11904.3 EMG47926.1 - 0.005 16.0 0.1 0.005 16.0 0.1 1.1 1 0 0 1 1 1 1 GPCR-chaperone LRR_8 PF13855.1 EMG47927.1 - 1.6e-05 24.5 17.7 0.013 15.2 0.1 5.9 4 1 0 5 5 5 3 Leucine rich repeat LRR_5 PF13306.1 EMG47927.1 - 0.14 11.8 7.7 0.068 12.8 0.3 3.3 3 1 1 4 4 4 0 Leucine rich repeats (6 copies) Phenol_hyd_sub PF06099.6 EMG47927.1 - 1.2 9.0 6.3 4.9 7.0 0.1 3.2 3 0 0 3 3 3 0 Phenol hydroxylase subunit Prenyltransf PF01255.14 EMG47928.1 - 6.8e-77 257.5 0.0 8.5e-77 257.2 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase HSF_DNA-bind PF00447.12 EMG47929.1 - 7.6e-35 119.2 1.4 7.6e-35 119.2 1.0 1.9 2 0 0 2 2 2 1 HSF-type DNA-binding Mss4 PF04421.8 EMG47930.1 - 1e-08 34.8 0.7 1.1e-06 28.3 0.4 2.4 1 1 0 1 1 1 1 Mss4 protein DUF2702 PF10863.3 EMG47932.1 - 1.5e-26 92.8 12.8 1.1e-25 89.9 8.9 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2702) DUF3245 PF11595.3 EMG47932.1 - 0.0024 18.1 13.6 0.0035 17.6 9.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3245) Sporozoite_P67 PF05642.6 EMG47932.1 - 0.03 12.1 2.7 0.033 12.0 1.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1399 PF07173.7 EMG47933.1 - 1.5e-38 132.1 6.3 3e-35 121.4 0.2 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1399) Recep_L_domain PF01030.19 EMG47934.1 - 7.2e-07 29.1 18.3 0.0026 17.6 0.5 3.8 2 2 1 3 3 3 3 Receptor L domain LRR_9 PF14580.1 EMG47934.1 - 0.34 10.4 4.7 0.58 9.6 2.4 2.0 1 1 1 2 2 2 0 Leucine-rich repeat Saw1 PF11561.3 EMG47934.1 - 1 8.7 6.5 1.9 7.8 4.5 1.4 1 0 0 1 1 1 0 Single strand annealing-weakened 1 Macoilin PF09726.4 EMG47934.1 - 4.1 5.5 6.6 5.7 5.0 4.6 1.1 1 0 0 1 1 1 0 Transmembrane protein AF-4 PF05110.8 EMG47934.1 - 6.8 4.4 21.2 8.7 4.0 14.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein F-box-like PF12937.2 EMG47935.1 - 1.6e-09 37.3 1.6 3.7e-09 36.1 1.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EMG47935.1 - 2.1e-09 36.8 6.4 0.33 10.6 0.0 7.0 5 2 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG47935.1 - 2.1e-08 33.7 9.7 0.077 12.7 0.0 6.1 4 2 3 7 7 7 5 Leucine rich repeat F-box PF00646.28 EMG47935.1 - 0.0019 17.8 1.1 0.0054 16.3 0.2 2.3 2 0 0 2 2 2 1 F-box domain DUF1699 PF08004.6 EMG47935.1 - 0.0054 16.2 2.1 1.9 8.0 0.1 4.2 5 0 0 5 5 5 1 Protein of unknown function (DUF1699) PTE PF02126.13 EMG47935.1 - 0.022 13.8 0.0 0.53 9.2 0.0 2.2 2 0 0 2 2 2 0 Phosphotriesterase family F-box-like_2 PF13013.1 EMG47935.1 - 1 9.1 5.5 1.2 8.8 0.6 3.1 2 1 1 3 3 3 0 F-box-like domain PCI PF01399.22 EMG47936.1 - 1.7e-07 31.5 0.8 2.2e-06 27.9 0.2 2.9 2 1 0 2 2 2 1 PCI domain TPR_8 PF13181.1 EMG47936.1 - 0.0035 17.0 1.0 0.024 14.4 0.7 2.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMG47936.1 - 0.024 14.5 0.4 0.13 12.2 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMG47936.1 - 0.1 12.5 0.0 0.53 10.2 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat PUF PF00806.14 EMG47937.1 - 2.7e-22 76.9 3.1 9.1e-06 24.8 0.0 6.5 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat eIF-5_eIF-2B PF01873.12 EMG47938.1 - 1.2e-40 137.9 0.0 1.8e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 BID PF06393.6 EMG47938.1 - 0.0088 15.4 0.6 0.016 14.5 0.4 1.4 1 0 0 1 1 1 1 BH3 interacting domain (BID) Fip1 PF05182.8 EMG47939.1 - 3.3e-22 77.4 0.1 3.3e-22 77.4 0.1 1.6 2 0 0 2 2 2 1 Fip1 motif Sporozoite_P67 PF05642.6 EMG47939.1 - 0.12 10.1 15.1 0.16 9.8 10.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Myc_N PF01056.13 EMG47939.1 - 0.29 10.2 10.7 0.41 9.7 7.4 1.3 1 0 0 1 1 1 0 Myc amino-terminal region BTV_NS2 PF04514.7 EMG47939.1 - 1.4 7.6 9.0 1.7 7.4 6.2 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Vfa1 PF08432.5 EMG47939.1 - 1.7 8.6 11.8 2.2 8.2 8.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2457 PF10446.4 EMG47939.1 - 2.4 6.8 24.0 3.4 6.2 16.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) S-antigen PF05756.6 EMG47939.1 - 5 7.1 10.3 11 6.1 7.1 1.6 1 0 0 1 1 1 0 S-antigen protein IFT57 PF10498.4 EMG47939.1 - 5.1 5.7 11.9 7.2 5.2 8.2 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 FAM176 PF14851.1 EMG47939.1 - 8.1 6.1 11.3 7.5 6.2 7.0 1.5 1 1 0 1 1 1 0 FAM176 family EBV-NA3 PF05009.7 EMG47939.1 - 8.4 5.5 8.1 13 4.9 5.6 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) RXT2_N PF08595.6 EMG47939.1 - 8.4 6.1 10.7 16 5.2 7.4 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF1399 PF07173.7 EMG47940.1 - 1.2e-38 132.5 3.5 6.1e-35 120.4 0.1 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1399) Anillin PF08174.6 EMG47941.1 - 5.5e-19 68.6 0.2 3.8e-18 65.8 0.2 2.6 1 1 0 1 1 1 1 Cell division protein anillin PH PF00169.24 EMG47941.1 - 2.2e-09 37.4 0.1 2.2e-09 37.4 0.1 3.1 4 0 0 4 4 4 1 PH domain FerA PF08165.6 EMG47941.1 - 0.035 13.7 0.1 0.11 12.2 0.1 1.8 1 0 0 1 1 1 0 FerA (NUC095) domain RRM_6 PF14259.1 EMG47942.1 - 7.3e-07 29.0 0.0 4.4e-06 26.5 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMG47942.1 - 9e-05 22.0 0.4 0.00031 20.2 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG47942.1 - 0.00059 19.6 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyclase_polyket PF04673.7 EMG47942.1 - 0.056 13.4 0.0 0.35 10.9 0.1 2.2 2 0 0 2 2 2 0 Polyketide synthesis cyclase ESCRT-II PF05871.7 EMG47943.1 - 4e-43 146.6 2.0 6.2e-43 146.0 0.8 1.6 1 1 1 2 2 2 1 ESCRT-II complex subunit TPP1 PF10341.4 EMG47943.1 - 0.018 14.9 0.5 0.083 12.8 0.2 1.9 2 0 0 2 2 2 0 Shelterin complex subunit, TPP1/ACD Ribosomal_L9_N PF01281.14 EMG47943.1 - 0.052 12.8 0.1 8.5 5.7 0.0 2.8 3 0 0 3 3 3 0 Ribosomal protein L9, N-terminal domain CAP59_mtransfer PF11735.3 EMG47943.1 - 0.054 12.7 0.5 4.7 6.3 0.1 2.0 2 0 0 2 2 2 0 Cryptococcal mannosyltransferase 1 Lipoprotein_17 PF04200.7 EMG47943.1 - 1.5 8.9 8.2 2.4 8.3 2.7 2.4 2 0 0 2 2 2 0 Lipoprotein associated domain Ribosomal_L37ae PF01780.14 EMG47944.1 - 1.2e-38 130.8 9.4 1.4e-38 130.6 6.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-H2C2_2 PF13465.1 EMG47944.1 - 0.0078 16.4 0.8 0.7 10.2 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.2 EMG47944.1 - 0.0088 15.8 5.0 0.015 15.1 3.4 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1364 PF07102.7 EMG47944.1 - 0.035 13.9 1.0 0.045 13.6 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) Rep_fac-A_C PF08646.5 EMG47944.1 - 0.052 13.2 0.4 0.075 12.7 0.3 1.4 1 0 0 1 1 1 0 Replication factor-A C terminal domain OrfB_Zn_ribbon PF07282.6 EMG47944.1 - 0.058 13.0 1.8 0.1 12.2 1.2 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain CarbpepA_inh PF02977.10 EMG47944.1 - 0.11 12.1 0.8 0.11 12.1 0.5 2.0 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor C1_1 PF00130.17 EMG47944.1 - 0.18 11.5 2.0 0.28 10.9 1.4 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.5 EMG47944.1 - 0.35 10.3 2.7 8.6 5.9 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-BED PF02892.10 EMG47944.1 - 0.38 10.5 5.1 0.79 9.5 0.3 2.3 1 1 1 2 2 2 0 BED zinc finger Elf1 PF05129.8 EMG47944.1 - 0.5 10.0 3.1 1.2 8.9 2.2 1.7 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C4_ClpX PF06689.8 EMG47944.1 - 0.72 9.4 4.4 2.1 7.9 3.0 1.9 1 1 0 1 1 1 0 ClpX C4-type zinc finger RRM_6 PF14259.1 EMG47945.1 - 0.00072 19.4 0.0 0.00098 19.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Arginase PF00491.16 EMG47946.1 - 1.7e-69 234.2 0.0 1.9e-69 234.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family GDPD PF03009.12 EMG47947.1 - 5.5e-71 239.0 1.6 7.8e-71 238.5 0.3 2.0 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EMG47947.1 - 9.8e-27 93.1 0.0 4.9e-09 36.4 0.0 4.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMG47947.1 - 6.8e-26 88.7 0.0 2.5e-05 23.8 0.0 6.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 EMG47947.1 - 1.4e-23 82.7 0.9 2.6e-07 30.9 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeats (many copies) SPX PF03105.14 EMG47947.1 - 3.3e-21 76.3 26.3 2.7e-17 63.4 12.2 4.9 4 1 0 4 4 4 1 SPX domain Ank_3 PF13606.1 EMG47947.1 - 2.7e-20 70.4 0.9 1.9e-05 24.4 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 EMG47947.1 - 8e-17 60.8 0.2 0.00042 20.4 0.0 5.1 2 2 3 5 5 5 3 Ankyrin repeats (many copies) TIP41 PF04176.8 EMG47948.1 - 4.9e-72 240.9 0.3 4.9e-72 240.9 0.2 1.7 2 0 0 2 2 2 1 TIP41-like family Sod_Fe_C PF02777.13 EMG47948.1 - 2.3e-09 37.0 4.1 0.00048 19.9 2.0 2.4 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain PRF PF06875.6 EMG47949.1 - 0.0027 16.9 0.4 0.0042 16.3 0.3 1.3 1 0 0 1 1 1 1 Plethodontid receptivity factor PRF TPR_11 PF13414.1 EMG47950.1 - 2.5e-05 23.8 0.1 6.3e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EMG47950.1 - 0.0003 20.4 0.0 0.0016 18.2 0.0 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMG47950.1 - 0.00033 20.2 3.2 0.00036 20.1 0.2 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMG47950.1 - 0.0063 16.0 0.1 0.023 14.2 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMG47950.1 - 0.012 15.7 0.5 0.27 11.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EMG47950.1 - 0.071 13.4 0.1 0.76 10.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat FANCI_S2 PF14676.1 EMG47950.1 - 0.16 11.8 1.1 0.33 10.8 0.2 2.0 2 0 0 2 2 2 0 FANCI solenoid 2 CTP_synth_N PF06418.9 EMG47952.1 - 2e-119 397.7 1.0 3e-119 397.1 0.7 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EMG47952.1 - 4e-53 179.7 0.0 6e-53 179.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EMG47952.1 - 1.6e-07 30.9 0.0 4.3e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 EMG47952.1 - 0.011 15.1 0.0 0.044 13.1 0.0 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Phage_tail_3 PF08813.6 EMG47952.1 - 0.077 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Phage tail protein MFS_1 PF07690.11 EMG47953.1 - 1.2e-24 86.7 29.4 1.4e-15 56.8 7.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG47953.1 - 5.6e-09 35.0 22.7 1.1e-08 34.0 15.7 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EMG47953.1 - 9.7e-09 34.1 11.7 9.7e-09 34.1 8.1 2.6 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 EMG47953.1 - 0.00046 18.4 3.3 0.096 10.7 0.1 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector ATG22 PF11700.3 EMG47953.1 - 0.0022 16.5 11.7 0.0022 16.5 8.1 2.6 2 1 0 2 2 2 1 Vacuole effluxer Atg22 like Metallophos PF00149.23 EMG47954.1 - 2.7e-05 23.6 3.3 0.00046 19.6 0.1 2.6 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMG47954.1 - 0.016 15.0 2.3 0.038 13.8 1.1 2.0 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Peptidase_C12 PF01088.16 EMG47956.1 - 1.3e-63 214.0 0.0 1.9e-63 213.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 CDV3 PF15359.1 EMG47956.1 - 1.6 8.8 3.7 0.96 9.5 0.7 1.9 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 Mito_carr PF00153.22 EMG47957.1 - 3.3e-73 241.4 1.5 2.6e-24 84.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ran_BP1 PF00638.13 EMG47959.1 - 2.8e-21 75.7 0.1 5.3e-21 74.9 0.1 1.5 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.6 EMG47959.1 - 2.6e-14 53.3 0.2 2.6e-14 53.3 0.1 7.0 6 3 2 8 8 8 1 NUP50 (Nucleoporin 50 kDa) Nucleoporin_FG PF13634.1 EMG47959.1 - 0.0019 18.3 16.1 0.0019 18.3 11.1 5.6 3 1 3 6 6 6 3 Nucleoporin FG repeat region WH1 PF00568.18 EMG47959.1 - 0.061 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 WH1 domain Copine PF07002.11 EMG47959.1 - 8.8 6.0 5.7 24 4.6 0.1 3.9 2 1 2 4 4 4 0 Copine RabGAP-TBC PF00566.13 EMG47960.1 - 2e-07 30.7 13.3 2e-07 30.7 9.2 3.5 4 1 1 5 5 5 1 Rab-GTPase-TBC domain ABC_tran PF00005.22 EMG47961.1 - 1.7e-46 157.9 0.0 1.3e-23 83.8 0.0 4.3 3 2 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EMG47961.1 - 5.3e-17 62.7 0.0 0.0013 18.7 0.0 4.8 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 EMG47961.1 - 1.3e-14 53.9 0.2 3.6e-05 23.0 0.0 4.1 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EMG47961.1 - 4.3e-10 40.2 4.6 0.0028 18.0 0.0 3.9 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.1 EMG47961.1 - 1.2e-09 37.4 0.0 0.0015 17.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EMG47961.1 - 2.9e-09 36.3 0.0 0.00022 20.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EMG47961.1 - 3.3e-08 34.3 0.6 0.0049 17.6 0.0 3.5 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EMG47961.1 - 1e-07 32.1 0.0 0.0023 18.0 0.0 3.5 4 0 0 4 4 2 2 AAA domain AAA_28 PF13521.1 EMG47961.1 - 1.3e-07 31.7 0.1 0.003 17.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EMG47961.1 - 2.9e-07 30.4 0.1 0.0063 16.4 0.0 3.5 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 EMG47961.1 - 7e-07 28.9 0.1 0.19 11.1 0.0 3.8 4 0 0 4 4 4 2 AAA-like domain SbcCD_C PF13558.1 EMG47961.1 - 2.7e-06 27.1 0.0 0.01 15.7 0.0 3.4 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 EMG47961.1 - 5.9e-06 26.4 0.0 0.15 12.2 0.0 3.4 3 0 0 3 3 2 2 RNA helicase Miro PF08477.8 EMG47961.1 - 6.4e-06 26.6 0.0 0.15 12.5 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 EMG47961.1 - 1.1e-05 25.2 0.0 0.0011 18.7 0.0 3.1 2 0 0 2 2 2 1 Dynamin family AAA_33 PF13671.1 EMG47961.1 - 1.3e-05 25.0 0.0 0.21 11.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EMG47961.1 - 1.9e-05 23.6 0.1 0.1 11.3 0.0 2.5 2 0 0 2 2 2 2 ArgK protein AAA PF00004.24 EMG47961.1 - 2.2e-05 24.6 0.5 0.58 10.3 0.0 4.5 5 0 0 5 5 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMG47961.1 - 3.7e-05 23.7 1.0 0.09 12.7 0.1 4.0 3 1 0 3 3 3 1 AAA ATPase domain MobB PF03205.9 EMG47961.1 - 3.9e-05 23.3 0.0 0.27 10.9 0.0 3.2 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EMG47961.1 - 4.6e-05 23.7 4.7 0.048 13.9 0.0 4.2 5 0 0 5 5 3 1 AAA domain Arch_ATPase PF01637.13 EMG47961.1 - 0.00016 21.4 0.0 0.4 10.3 0.0 3.3 2 0 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 EMG47961.1 - 0.0002 21.2 0.0 2.1 8.2 0.0 3.6 3 0 0 3 3 3 2 AAA domain MutS_V PF00488.16 EMG47961.1 - 0.00038 19.9 0.1 0.15 11.4 0.0 2.4 2 0 0 2 2 2 1 MutS domain V PduV-EutP PF10662.4 EMG47961.1 - 0.00041 19.8 0.0 0.19 11.2 0.0 3.0 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation HEAT_2 PF13646.1 EMG47961.1 - 0.00061 20.0 3.2 0.081 13.2 0.0 3.6 1 1 2 3 3 3 1 HEAT repeats NACHT PF05729.7 EMG47961.1 - 0.0012 18.4 0.0 0.58 9.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain cobW PF02492.14 EMG47961.1 - 0.0012 18.2 0.1 1.2 8.5 0.0 3.3 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EMG47961.1 - 0.0016 18.0 0.0 2.8 7.4 0.0 3.5 4 0 0 4 4 3 1 AAA domain DUF87 PF01935.12 EMG47961.1 - 0.0022 17.8 4.1 0.33 10.7 0.0 4.4 5 0 0 5 5 4 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EMG47961.1 - 0.0034 16.8 0.7 2.9 7.2 0.0 3.8 4 0 0 4 4 4 1 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EMG47961.1 - 0.0081 15.2 0.0 3.1 6.8 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin Cnd1 PF12717.2 EMG47961.1 - 0.015 15.1 0.0 0.15 11.9 0.0 2.5 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 UME PF08064.8 EMG47961.1 - 0.015 15.2 0.3 0.043 13.7 0.2 1.9 1 0 0 1 1 1 0 UME (NUC010) domain CLASP_N PF12348.3 EMG47961.1 - 0.015 14.6 0.5 5.3 6.3 0.0 3.0 2 1 0 3 3 3 0 CLASP N terminal MMS19_C PF12460.3 EMG47961.1 - 0.016 13.9 2.0 0.055 12.1 0.1 2.5 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal Septin PF00735.13 EMG47961.1 - 0.028 13.4 0.8 1.9 7.4 0.0 3.2 3 1 0 3 3 3 0 Septin Mg_chelatase PF01078.16 EMG47961.1 - 0.031 13.4 0.1 1.2 8.2 0.0 2.8 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EMG47961.1 - 0.038 13.7 0.0 5.9 6.7 0.0 3.0 2 0 0 2 2 2 0 Part of AAA domain IstB_IS21 PF01695.12 EMG47961.1 - 0.047 13.1 0.0 7.8 5.8 0.0 2.9 3 0 0 3 3 2 0 IstB-like ATP binding protein HEAT PF02985.17 EMG47961.1 - 0.057 13.5 0.2 27 5.1 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat AAA_13 PF13166.1 EMG47961.1 - 0.081 11.3 12.6 2.1 6.6 0.0 4.6 5 0 0 5 5 5 0 AAA domain DUF937 PF06078.6 EMG47961.1 - 0.13 12.5 0.0 25 5.1 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF937) DUF3349 PF11829.3 EMG47961.1 - 0.36 11.2 2.4 0.85 10.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) HEAT_EZ PF13513.1 EMG47961.1 - 0.4 11.2 6.6 6.1 7.4 0.0 4.4 4 1 1 5 5 4 0 HEAT-like repeat Acetyltransf_7 PF13508.1 EMG47962.1 - 0.00031 20.8 1.4 0.015 15.4 0.9 3.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMG47962.1 - 0.053 13.3 0.1 2 8.3 0.0 2.7 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain DUF1107 PF06526.7 EMG47962.1 - 2.4 8.0 4.5 6.7 6.6 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1107) LRR_8 PF13855.1 EMG47963.1 - 2.3e-10 40.0 24.4 1.2e-08 34.6 0.6 6.9 8 1 1 9 9 9 4 Leucine rich repeat LRR_4 PF12799.2 EMG47963.1 - 2.6e-08 33.2 32.5 9.2e-05 21.9 1.5 8.9 8 2 1 9 9 9 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMG47963.1 - 0.00013 21.5 19.3 0.067 13.2 0.4 8.6 8 1 1 9 9 9 2 Leucine Rich Repeat FNIP PF05725.7 EMG47963.1 - 0.0004 20.2 16.5 1.3 9.0 0.0 7.5 6 2 1 7 7 7 3 FNIP Repeat LRR_7 PF13504.1 EMG47963.1 - 0.00074 19.3 10.5 0.67 10.3 0.2 8.5 9 1 0 9 9 9 1 Leucine rich repeat LRR_6 PF13516.1 EMG47963.1 - 0.032 14.2 16.6 4 7.7 0.4 7.3 6 2 1 7 7 7 0 Leucine Rich repeat LRR_5 PF13306.1 EMG47963.1 - 0.048 13.3 16.2 0.22 11.2 0.6 4.4 4 0 0 4 4 4 0 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EMG47964.1 - 1.8e-13 50.0 16.9 3.2e-09 36.3 0.1 6.8 6 1 1 7 7 7 3 Leucine rich repeat LRR_4 PF12799.2 EMG47964.1 - 5e-08 32.3 24.7 0.00012 21.6 1.1 8.3 5 3 2 8 8 8 3 Leucine Rich repeats (2 copies) FNIP PF05725.7 EMG47964.1 - 1.2e-06 28.3 13.9 0.2 11.6 0.3 7.8 6 3 1 7 7 7 3 FNIP Repeat LRR_7 PF13504.1 EMG47964.1 - 0.00057 19.6 12.5 4 8.0 0.1 9.3 10 0 0 10 10 10 1 Leucine rich repeat LRR_6 PF13516.1 EMG47964.1 - 0.0028 17.5 11.1 8.2 6.8 0.1 7.1 5 1 1 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.28 EMG47964.1 - 0.045 13.7 25.4 0.38 10.9 0.2 8.4 10 1 1 11 11 11 0 Leucine Rich Repeat F-box-like PF12937.2 EMG47964.1 - 0.69 9.6 2.7 0.63 9.8 0.3 2.2 2 0 0 2 2 2 0 F-box-like AA_permease PF00324.16 EMG47965.1 - 4.9e-117 391.2 38.1 5.7e-117 390.9 26.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG47965.1 - 1.2e-35 122.9 38.7 1.4e-35 122.6 26.8 1.0 1 0 0 1 1 1 1 Amino acid permease PH_9 PF15410.1 EMG47966.1 - 1.4e-06 28.4 0.2 5e-06 26.6 0.2 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain Polyketide_cyc PF03364.15 EMG47968.1 - 3.8e-14 52.7 0.0 4.4e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EMG47968.1 - 0.075 13.2 0.0 0.095 12.8 0.0 1.1 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Ribosomal_S25 PF03297.10 EMG47969.1 - 3.5e-45 152.3 3.9 3.9e-45 152.2 2.7 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Ftsk_gamma PF09397.5 EMG47969.1 - 8.8e-05 22.1 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Ftsk gamma domain HTH_CodY PF08222.6 EMG47969.1 - 0.058 12.7 0.1 0.096 12.0 0.1 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_20 PF12840.2 EMG47969.1 - 0.089 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain PLA2_B PF01735.13 EMG47970.1 - 6.4e-112 374.2 18.4 1.7e-87 293.6 5.6 3.0 1 1 0 2 2 2 2 Lysophospholipase catalytic domain Patatin PF01734.17 EMG47970.1 - 0.0016 18.4 0.0 0.0063 16.4 0.0 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase Glutaredoxin PF00462.19 EMG47971.1 - 1.4e-11 44.2 0.0 2.3e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 EMG47971.1 - 0.11 12.6 0.2 0.64 10.2 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like domain Ribosomal_S17 PF00366.15 EMG47972.1 - 2.6e-30 104.2 2.9 5e-30 103.3 2.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 Apc9 PF12856.2 EMG47973.1 - 1.7e-21 76.1 1.1 1.7e-21 76.1 0.8 3.5 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 9 Zip PF02535.17 EMG47973.1 - 3.5 6.5 6.8 5.6 5.8 4.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Pyr_redox_2 PF07992.9 EMG47974.1 - 1.7e-34 119.4 1.8 3.1e-34 118.6 1.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EMG47974.1 - 2.9e-33 114.1 0.2 2.8e-32 111.0 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EMG47974.1 - 2e-19 69.7 5.9 8.7e-17 61.3 0.8 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMG47974.1 - 2.3e-10 39.5 0.6 0.0011 17.5 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.1 EMG47974.1 - 2.8e-09 37.3 0.2 2.1e-06 27.9 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMG47974.1 - 2.3e-07 30.2 0.1 3.5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EMG47974.1 - 9.2e-06 24.7 0.1 9.2e-06 24.7 0.0 2.9 3 1 0 4 4 4 1 Glucose inhibited division protein A DAO PF01266.19 EMG47974.1 - 3.2e-05 23.0 0.0 3.2e-05 23.0 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMG47974.1 - 0.0006 18.7 1.5 0.002 17.0 1.0 1.8 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.14 EMG47974.1 - 0.00065 18.8 0.7 0.68 9.0 0.0 3.1 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EMG47974.1 - 0.00096 18.7 0.1 0.29 10.6 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EMG47974.1 - 0.002 17.2 1.3 0.0053 15.8 0.1 2.3 3 0 0 3 3 3 1 Thi4 family NAD_binding_8 PF13450.1 EMG47974.1 - 0.0027 17.7 1.8 0.0027 17.7 1.3 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EMG47974.1 - 0.0037 16.2 0.0 0.0059 15.5 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 EMG47974.1 - 0.0044 17.2 0.1 0.068 13.4 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.14 EMG47974.1 - 0.046 12.7 1.2 0.67 8.9 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 EMG47974.1 - 0.076 12.3 1.1 0.29 10.5 0.1 2.4 2 1 1 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EMG47974.1 - 0.12 12.0 6.1 0.63 9.6 0.1 2.5 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Zn_clus PF00172.13 EMG47975.1 - 3.7e-09 36.3 6.8 9.2e-09 35.0 4.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC1 PF03109.11 EMG47976.1 - 4.5e-34 116.9 0.0 1.2e-33 115.5 0.0 1.8 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 EMG47976.1 - 0.00053 19.3 0.1 0.007 15.7 0.0 2.5 3 0 0 3 3 3 1 RIO1 family rRNA_processing PF08524.6 EMG47977.1 - 3.4e-39 133.9 24.2 4e-39 133.7 16.8 1.0 1 0 0 1 1 1 1 rRNA processing PRP3 PF08572.5 EMG47977.1 - 0.35 10.2 15.5 0.022 14.1 7.0 1.7 1 1 1 2 2 2 0 pre-mRNA processing factor 3 (PRP3) Mis12 PF05859.7 EMG47977.1 - 1.7 8.4 6.6 2 8.1 0.7 2.2 1 1 1 2 2 2 0 Mis12 protein HTH_32 PF13565.1 EMG47977.1 - 2.8 8.8 7.8 0.64 10.8 2.3 2.1 1 1 1 2 2 2 0 Homeodomain-like domain DUF2638 PF10937.3 EMG47978.1 - 1.3e-06 29.3 1.8 7.3e-06 26.9 1.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2638) DUF410 PF04190.8 EMG47980.1 - 2e-30 106.1 1.8 5.4e-30 104.8 1.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF410) NUDIX PF00293.23 EMG47981.1 - 1.5e-17 63.5 0.1 1.9e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Zn_clus PF00172.13 EMG47983.1 - 1.4e-08 34.4 11.6 2.7e-08 33.5 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rad9_Rad53_bind PF08605.5 EMG47984.1 - 3.6e-36 123.8 0.6 7.9e-36 122.7 0.4 1.6 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 EMG47984.1 - 1.3e-08 34.8 2.9 4.1e-05 23.6 0.0 3.0 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Pro_dh PF01619.13 EMG47985.1 - 1e-48 165.9 1.2 1.2e-48 165.7 0.9 1.2 1 0 0 1 1 1 1 Proline dehydrogenase HR1 PF02185.11 EMG47985.1 - 0.026 14.2 0.4 2.3 8.0 0.1 2.8 2 0 0 2 2 2 0 Hr1 repeat HSP9_HSP12 PF04119.7 EMG47986.1 - 9.1e-28 96.1 3.6 9.1e-28 96.1 2.5 2.4 2 1 1 3 3 3 1 Heat shock protein 9/12 CPL PF08144.6 EMG47986.1 - 0.0042 16.9 1.7 0.0056 16.5 1.1 1.1 1 0 0 1 1 1 1 CPL (NUC119) domain BURP PF03181.10 EMG47986.1 - 0.012 14.7 0.9 0.014 14.5 0.6 1.1 1 0 0 1 1 1 0 BURP domain DUF883 PF05957.8 EMG47986.1 - 0.02 15.2 3.6 0.038 14.3 2.1 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) EcsC PF12787.2 EMG47986.1 - 0.058 12.7 3.2 0.073 12.4 2.2 1.0 1 0 0 1 1 1 0 EcsC protein family YflT PF11181.3 EMG47986.1 - 0.17 12.0 2.0 0.23 11.5 1.4 1.4 1 1 0 1 1 1 0 Heat induced stress protein YflT Mt_ATP-synt_B PF05405.9 EMG47986.1 - 0.21 11.0 2.6 6.8 6.1 0.2 2.1 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Sterol_MT_C PF08498.5 EMG47986.1 - 0.21 11.5 0.5 2.8 7.9 0.0 2.5 2 0 0 2 2 2 0 Sterol methyltransferase C-terminal ERp29 PF07749.7 EMG47986.1 - 0.69 10.5 7.6 0.42 11.2 2.2 2.1 1 1 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain MT0933_antitox PF14013.1 EMG47986.1 - 0.84 9.7 13.6 0.76 9.9 3.0 3.2 1 1 1 2 2 2 0 MT0933-like antitoxin protein ATP-synt_B PF00430.13 EMG47986.1 - 4.2 7.1 9.1 3.8 7.3 4.3 1.9 1 1 0 2 2 2 0 ATP synthase B/B' CF(0) AAA PF00004.24 EMG47987.1 - 3.1e-96 318.6 0.2 1e-48 164.8 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EMG47987.1 - 3.4e-16 59.0 0.0 1.5e-09 37.2 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EMG47987.1 - 3.5e-13 49.8 0.0 3.4e-05 23.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EMG47987.1 - 3e-12 47.3 0.0 4.4e-07 30.7 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMG47987.1 - 5.5e-12 45.9 0.5 0.0017 18.5 0.0 5.2 3 2 0 3 3 2 2 AAA domain AAA_33 PF13671.1 EMG47987.1 - 1.3e-11 44.5 0.0 2.4e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EMG47987.1 - 2.2e-11 43.7 0.0 9.6e-05 22.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EMG47987.1 - 2.6e-11 43.8 0.4 0.00053 20.0 0.0 3.9 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 EMG47987.1 - 1.1e-10 41.3 1.5 9.1e-05 22.2 0.0 4.0 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EMG47987.1 - 2.7e-10 39.6 0.0 0.00055 19.0 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 EMG47987.1 - 3.8e-08 32.4 0.0 0.0012 17.6 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 EMG47987.1 - 5.1e-08 32.5 4.4 0.1 11.9 0.1 4.4 2 2 1 4 4 4 2 AAA domain Mg_chelatase PF01078.16 EMG47987.1 - 6e-08 32.0 0.2 0.0035 16.5 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EMG47987.1 - 7.1e-08 32.5 0.0 0.0011 18.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EMG47987.1 - 9.5e-08 32.1 0.0 0.011 15.9 0.0 3.3 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 EMG47987.1 - 1.4e-07 31.9 9.5 3.9e-05 23.9 0.0 4.5 5 1 0 5 5 3 2 AAA domain ABC_tran PF00005.22 EMG47987.1 - 1.8e-07 31.5 7.9 0.0017 18.6 0.0 4.2 3 2 0 3 3 2 2 ABC transporter AAA_19 PF13245.1 EMG47987.1 - 2e-07 30.6 0.9 0.026 14.2 0.0 3.1 3 1 0 3 3 2 2 Part of AAA domain IstB_IS21 PF01695.12 EMG47987.1 - 6.2e-07 28.9 2.2 0.019 14.4 0.0 3.1 3 0 0 3 3 3 2 IstB-like ATP binding protein Cytidylate_kin2 PF13189.1 EMG47987.1 - 1.5e-06 28.2 0.0 0.00054 19.9 0.0 2.9 2 0 0 2 2 2 1 Cytidylate kinase-like family Vps4_C PF09336.5 EMG47987.1 - 1.6e-06 27.8 0.2 0.0006 19.6 0.1 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain NACHT PF05729.7 EMG47987.1 - 2.1e-06 27.4 0.5 0.065 12.8 0.0 3.6 3 1 1 4 4 3 2 NACHT domain AAA_3 PF07726.6 EMG47987.1 - 3.3e-06 26.7 0.0 0.022 14.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EMG47987.1 - 3.5e-06 26.8 0.4 0.066 12.9 0.0 4.5 3 2 2 5 5 5 1 Archaeal ATPase SKI PF01202.17 EMG47987.1 - 6.4e-06 26.1 0.0 0.031 14.1 0.0 2.9 2 0 0 2 2 2 2 Shikimate kinase Rad17 PF03215.10 EMG47987.1 - 0.0001 21.1 0.0 0.031 12.9 0.0 2.5 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 EMG47987.1 - 0.00014 21.5 0.1 0.14 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EMG47987.1 - 0.00015 21.8 0.0 0.81 9.7 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain KaiC PF06745.8 EMG47987.1 - 0.00015 20.9 0.3 0.7 8.9 0.0 3.4 2 1 1 3 3 3 1 KaiC DUF815 PF05673.8 EMG47987.1 - 0.00019 20.4 0.0 0.056 12.3 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 EMG47987.1 - 0.00019 21.0 0.0 0.74 9.2 0.0 2.6 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain Viral_helicase1 PF01443.13 EMG47987.1 - 0.0003 20.4 1.2 0.54 9.7 0.0 3.4 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 EMG47987.1 - 0.00035 19.5 0.0 0.69 8.7 0.0 2.8 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activat PF00158.21 EMG47987.1 - 0.00042 19.8 0.0 0.41 10.0 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain PduV-EutP PF10662.4 EMG47987.1 - 0.00053 19.4 0.0 0.17 11.3 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_11 PF13086.1 EMG47987.1 - 0.00058 19.5 4.1 1.1 8.7 0.0 3.4 3 1 0 3 3 3 1 AAA domain NTPase_1 PF03266.10 EMG47987.1 - 0.0011 18.7 0.0 0.75 9.4 0.0 2.8 2 0 0 2 2 2 1 NTPase PhoH PF02562.11 EMG47987.1 - 0.0012 18.1 0.2 0.93 8.6 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein Parvo_NS1 PF01057.12 EMG47987.1 - 0.0031 16.4 0.0 2.4 6.9 0.0 2.5 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 MMR_HSR1 PF01926.18 EMG47987.1 - 0.0034 17.3 0.0 0.12 12.3 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 EMG47987.1 - 0.0036 16.5 0.2 1.6 7.8 0.0 3.6 4 0 0 4 4 2 1 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 EMG47987.1 - 0.0067 15.8 5.5 0.39 10.1 0.0 4.2 4 2 0 4 4 4 1 AAA-like domain DUF258 PF03193.11 EMG47987.1 - 0.007 15.5 0.0 0.14 11.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 KTI12 PF08433.5 EMG47987.1 - 0.0076 15.4 4.1 0.7 9.0 0.0 4.2 4 0 0 4 4 4 1 Chromatin associated protein KTI12 UPF0079 PF02367.12 EMG47987.1 - 0.0087 15.6 0.1 0.88 9.2 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 EMG47987.1 - 0.0097 14.8 0.0 1.7 7.4 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein Bac_DnaA PF00308.13 EMG47987.1 - 0.014 15.0 0.0 1.9 8.0 0.0 3.3 2 2 0 2 2 2 0 Bacterial dnaA protein Miro PF08477.8 EMG47987.1 - 0.017 15.5 0.0 3.6 8.0 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein FeoB_N PF02421.13 EMG47987.1 - 0.023 13.9 1.0 0.55 9.4 0.0 3.1 4 0 0 4 4 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 EMG47987.1 - 0.029 13.8 0.0 0.43 10.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain CPT PF07931.7 EMG47987.1 - 0.038 13.6 0.0 0.32 10.5 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_31 PF13614.1 EMG47987.1 - 0.049 13.5 0.0 0.84 9.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain ADK PF00406.17 EMG47987.1 - 0.049 13.5 0.7 2.7 7.8 0.0 2.8 3 0 0 3 3 2 0 Adenylate kinase AFG1_ATPase PF03969.11 EMG47987.1 - 0.062 12.1 0.0 7.2 5.3 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase FtsK_SpoIIIE PF01580.13 EMG47987.1 - 0.064 12.7 0.3 12 5.2 0.1 3.2 2 1 0 2 2 2 0 FtsK/SpoIIIE family DDHD PF02862.12 EMG47987.1 - 0.29 10.8 7.0 0.65 9.7 4.8 1.5 1 0 0 1 1 1 0 DDHD domain NAD_binding_5 PF07994.7 EMG47987.1 - 2 7.8 6.3 2.5 7.5 3.0 2.0 2 0 0 2 2 2 0 Myo-inositol-1-phosphate synthase Pyridox_oxidase PF01243.15 EMG47988.1 - 3.7e-13 49.3 0.0 2.3e-12 46.7 0.0 2.0 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 EMG47988.1 - 0.0031 17.3 0.0 0.016 15.0 0.0 2.0 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ORC4_C PF14629.1 EMG47989.1 - 2e-38 131.8 0.2 4e-38 130.8 0.1 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EMG47989.1 - 5.2e-16 59.1 0.0 8.9e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EMG47989.1 - 2.5e-10 40.4 1.6 5e-10 39.4 1.1 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EMG47989.1 - 5.9e-08 32.9 0.1 5.3e-07 29.8 0.0 2.4 2 1 1 3 3 3 1 AAA domain AAA PF00004.24 EMG47989.1 - 6.7e-06 26.3 0.2 2.9e-05 24.2 0.2 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EMG47989.1 - 2e-05 24.5 2.4 0.02 14.7 0.0 3.1 2 1 1 3 3 3 2 AAA domain NACHT PF05729.7 EMG47989.1 - 0.00072 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Arf PF00025.16 EMG47989.1 - 0.009 15.2 0.4 2 7.6 0.0 3.0 3 0 0 3 3 3 1 ADP-ribosylation factor family SRPRB PF09439.5 EMG47989.1 - 0.011 14.8 0.1 0.099 11.8 0.0 2.5 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF2765 PF10963.3 EMG47989.1 - 0.065 13.1 1.4 5.5 7.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2765) RGS PF00615.14 EMG47990.1 - 5.5e-13 49.0 3.7 5.5e-13 49.0 2.6 3.0 3 1 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.16 EMG47990.1 - 1.5e-10 40.6 0.0 3.8e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) GTP_EFTU PF00009.22 EMG47991.1 - 2.1e-38 131.6 0.0 3.4e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EMG47991.1 - 2.1e-35 120.6 0.2 4.4e-35 119.5 0.2 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EMG47991.1 - 4e-11 42.8 2.3 4.7e-11 42.6 0.5 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMG47991.1 - 0.0083 16.0 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PHD PF00628.24 EMG47992.1 - 5.7e-06 25.9 8.4 1.2e-05 24.8 5.9 1.5 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.8 EMG47992.1 - 7.4e-06 26.4 0.0 1.5e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.9 EMG47992.1 - 5.6e-05 23.1 0.8 5.6e-05 23.1 0.5 2.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PHD_2 PF13831.1 EMG47992.1 - 0.26 10.6 6.6 0.65 9.3 4.6 1.6 1 0 0 1 1 1 0 PHD-finger zf-PHD-like PF15446.1 EMG47992.1 - 3 7.0 10.4 0.039 13.2 1.0 2.3 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain Nop53 PF07767.6 EMG47993.1 - 0.013 14.5 3.9 0.012 14.6 2.7 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF4589 PF15252.1 EMG47993.1 - 0.081 12.7 2.0 4.8 6.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4589) Tho2 PF11262.3 EMG47993.1 - 0.2 10.6 3.1 0.26 10.2 2.1 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 SNARE PF05739.14 EMG47994.1 - 3.8e-12 45.7 4.8 3.8e-12 45.7 3.3 2.8 3 1 1 4 4 4 1 SNARE domain Syntaxin_2 PF14523.1 EMG47994.1 - 0.00022 21.1 6.5 0.00022 21.1 4.5 2.5 2 1 0 2 2 2 1 Syntaxin-like protein PhoU_div PF01865.11 EMG47994.1 - 0.0012 18.1 0.8 0.0012 18.1 0.6 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF47 DEAD_assoc PF08494.6 EMG47994.1 - 0.0022 17.7 1.8 0.0034 17.1 1.2 1.2 1 0 0 1 1 1 1 DEAD/H associated YjgP_YjgQ PF03739.9 EMG47994.1 - 0.02 13.6 1.0 0.025 13.3 0.7 1.3 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family Herpes_US9 PF06072.6 EMG47994.1 - 0.092 12.5 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 GNVR PF13807.1 EMG47994.1 - 0.12 12.1 0.3 0.33 10.7 0.2 1.8 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase DUF1664 PF07889.7 EMG47994.1 - 0.4 10.4 11.1 0.43 10.3 3.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.7 EMG47994.1 - 1.1 9.0 9.4 1.6 8.4 1.0 2.5 2 1 0 2 2 2 0 Laminin Domain II Synaptobrevin PF00957.16 EMG47994.1 - 1.3 8.6 6.5 0.36 10.4 0.7 2.6 2 1 1 3 3 3 0 Synaptobrevin ISG65-75 PF11727.3 EMG47994.1 - 1.6 7.7 14.0 5.7 5.9 0.9 2.9 1 1 2 3 3 3 0 Invariant surface glycoprotein MCPsignal PF00015.16 EMG47994.1 - 1.8 8.0 14.0 2.9 7.3 5.2 2.2 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Halo_GVPC PF05465.8 EMG47994.1 - 4.8 7.2 6.3 39 4.3 0.0 3.5 4 0 0 4 4 4 0 Halobacterial gas vesicle protein C (GVPC) repeat FliD_N PF02465.13 EMG47994.1 - 8.5 6.8 12.8 2.1 8.7 1.2 2.8 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus WD40 PF00400.27 EMG47995.1 - 3.1e-45 150.4 23.2 1.7e-11 43.5 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EMG47995.1 - 0.056 12.9 0.1 1.2 8.7 0.0 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Kelch_2 PF07646.10 EMG47995.1 - 0.067 12.9 1.4 4.8 7.1 0.1 3.5 4 0 0 4 4 4 0 Kelch motif PPV_E2_C PF00511.12 EMG47995.1 - 0.074 13.0 0.1 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 E2 (early) protein, C terminal Coatomer_WDAD PF04053.9 EMG47995.1 - 0.16 10.7 2.1 0.3 9.8 0.4 2.0 2 1 0 2 2 2 0 Coatomer WD associated region DUF1727 PF08353.5 EMG47995.1 - 0.42 10.2 2.1 43 3.7 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1727) FAD_binding_6 PF00970.19 EMG47996.1 - 2.5e-07 30.7 0.0 3.5e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EMG47996.1 - 0.00028 21.4 0.0 1.4 9.5 0.0 2.7 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Hira PF07569.6 EMG47997.1 - 4.5e-56 189.5 0.5 9.9e-56 188.3 0.3 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 EMG47997.1 - 7e-21 73.2 10.4 1.4e-05 24.8 0.8 7.5 8 0 0 8 8 8 5 WD domain, G-beta repeat HIRA_B PF09453.5 EMG47997.1 - 1.8e-10 40.0 4.1 4.5e-10 38.8 2.9 1.8 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 EMG47997.1 - 0.0021 17.6 0.0 1.1 8.9 0.0 2.9 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat CK_II_beta PF01214.13 EMG47998.1 - 7.6e-70 234.1 0.0 1e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit SPT6_acidic PF14632.1 EMG47998.1 - 0.059 13.5 0.2 0.15 12.2 0.1 1.7 2 0 0 2 2 2 0 Acidic N-terminal SPT6 tRNA-synt_1b PF00579.20 EMG47999.1 - 2.2e-70 237.0 0.0 3e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) CLTH PF10607.4 EMG47999.1 - 0.02 14.6 1.9 0.13 11.9 0.5 2.3 2 0 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain GATA PF00320.22 EMG48000.1 - 0.053 12.8 0.2 0.053 12.8 0.1 2.3 2 0 0 2 2 2 0 GATA zinc finger Mannosyl_trans3 PF11051.3 EMG48001.1 - 4.5e-68 229.5 0.9 5.8e-68 229.1 0.6 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative Mer2 PF09074.5 EMG48002.1 - 0.0047 16.8 12.6 0.055 13.3 8.7 2.2 1 1 0 1 1 1 1 Mer2 IncA PF04156.9 EMG48002.1 - 0.026 14.0 9.3 0.019 14.5 2.2 2.5 1 1 1 2 2 2 0 IncA protein DUF4200 PF13863.1 EMG48002.1 - 0.029 14.3 5.9 0.092 12.6 0.8 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) GAS PF13851.1 EMG48002.1 - 0.062 12.4 11.6 0.22 10.6 3.5 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Arfaptin PF06456.8 EMG48002.1 - 0.073 12.4 5.1 0.02 14.2 0.6 2.0 2 0 0 2 2 2 0 Arfaptin-like domain ADIP PF11559.3 EMG48002.1 - 0.08 12.8 8.7 0.17 11.7 1.2 2.9 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding SlyX PF04102.7 EMG48002.1 - 0.11 12.9 0.7 0.11 12.9 0.5 3.0 2 2 1 3 3 3 0 SlyX Sipho_Gp157 PF05565.6 EMG48002.1 - 0.17 11.4 4.9 0.26 10.8 0.5 2.3 2 1 1 3 3 3 0 Siphovirus Gp157 XhlA PF10779.4 EMG48002.1 - 0.17 11.7 6.9 3.9 7.4 2.3 2.8 2 0 0 2 2 2 0 Haemolysin XhlA BLOC1_2 PF10046.4 EMG48002.1 - 0.57 10.3 8.3 1.8 8.7 0.5 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 EMG48002.1 - 0.77 8.8 7.5 0.93 8.6 0.8 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Laminin_II PF06009.7 EMG48002.1 - 3.8 7.2 8.1 0.95 9.2 1.4 2.6 1 1 0 2 2 2 0 Laminin Domain II DUF16 PF01519.11 EMG48002.1 - 5.3 7.3 12.9 8.4 6.6 1.7 2.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 Bap31 PF05529.7 EMG48002.1 - 7.2 6.0 9.7 21 4.5 3.2 2.5 2 1 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF1664 PF07889.7 EMG48002.1 - 8.3 6.2 10.8 28 4.5 2.6 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Aldolase_II PF00596.16 EMG48003.1 - 2.3e-39 134.8 0.0 3.1e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Pyr_redox_2 PF07992.9 EMG48004.1 - 9.5e-28 97.4 0.2 1.1e-27 97.1 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMG48004.1 - 2.9e-16 59.6 0.5 5.4e-14 52.3 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMG48004.1 - 3.2e-10 40.4 0.0 1.3e-07 31.9 0.0 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMG48004.1 - 0.00036 19.5 4.3 0.46 9.2 0.1 3.8 3 1 1 4 4 4 2 Glucose inhibited division protein A Thi4 PF01946.12 EMG48004.1 - 0.00046 19.3 0.2 0.0048 16.0 0.0 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EMG48004.1 - 0.00049 19.1 0.2 1.1 8.0 0.0 3.1 1 1 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EMG48004.1 - 0.0027 16.6 0.0 0.64 8.8 0.0 3.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 EMG48004.1 - 0.0037 17.4 0.0 0.9 9.8 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 EMG48004.1 - 0.004 17.1 0.1 0.016 15.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMG48004.1 - 0.004 16.0 1.1 1.6 7.4 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain Shikimate_DH PF01488.15 EMG48004.1 - 0.0096 16.0 0.4 2.1 8.4 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EMG48004.1 - 0.04 13.6 0.0 3.1 7.5 0.0 2.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 EMG48004.1 - 0.056 12.5 0.1 1.8 7.5 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase UPF0236 PF06782.6 EMG48004.1 - 0.1 10.9 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0236) DUF1189 PF06691.6 EMG48006.1 - 0.025 13.8 0.7 11 5.3 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1189) FlgH PF02107.11 EMG48006.1 - 0.082 12.4 0.0 0.78 9.2 0.0 2.2 2 0 0 2 2 2 0 Flagellar L-ring protein Mannosyl_trans3 PF11051.3 EMG48008.1 - 2.1e-71 240.4 0.6 2.7e-71 240.0 0.4 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative DUF605 PF04652.11 EMG48009.1 - 0.00043 19.7 6.0 0.00043 19.7 4.1 2.2 2 0 0 2 2 2 1 Vta1 like Usp PF00582.21 EMG48010.1 - 0.0081 16.3 0.1 0.15 12.2 0.0 2.6 2 1 0 2 2 2 1 Universal stress protein family NOA36 PF06524.7 EMG48010.1 - 9.7 5.3 10.8 17 4.5 7.5 1.3 1 0 0 1 1 1 0 NOA36 protein Per1 PF04080.8 EMG48011.1 - 2.5e-87 292.7 18.8 3.3e-87 292.3 13.0 1.1 1 0 0 1 1 1 1 Per1-like Ceramidase PF05875.7 EMG48011.1 - 0.5 9.4 20.5 2 7.4 14.2 2.1 1 1 0 1 1 1 0 Ceramidase MFS_1 PF07690.11 EMG48012.1 - 0.0001 21.1 34.6 0.0001 21.1 22.3 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Cyclin_N PF00134.18 EMG48013.1 - 1e-12 47.6 0.5 2.2e-12 46.6 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain ADH_N PF08240.7 EMG48015.1 - 3e-30 104.1 0.8 5e-30 103.4 0.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMG48015.1 - 2.7e-22 78.6 0.0 6.8e-22 77.3 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EMG48015.1 - 6.5e-05 22.5 0.0 6.5e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Methyltransf_16 PF10294.4 EMG48015.1 - 0.094 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase zf-CXXC PF02008.15 EMG48015.1 - 0.13 12.0 0.7 0.24 11.2 0.5 1.3 1 0 0 1 1 1 0 CXXC zinc finger domain Fungal_trans PF04082.13 EMG48016.1 - 1.3e-20 73.4 3.2 2e-20 72.7 1.7 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG48016.1 - 5.7e-10 38.9 14.1 9.3e-10 38.2 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.16 EMG48017.1 - 1.6e-129 432.3 41.3 1.9e-129 432.1 28.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG48017.1 - 8.9e-34 116.7 46.5 1.2e-33 116.3 32.3 1.0 1 0 0 1 1 1 1 Amino acid permease JAB PF01398.16 EMG48018.1 - 1.7e-11 43.8 0.0 3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EMG48018.1 - 0.018 15.1 4.2 0.04 14.0 2.9 1.6 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function DUF2424 PF10340.4 EMG48019.1 - 3.1e-30 105.0 0.1 4.5e-30 104.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 EMG48019.1 - 1e-13 51.3 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMG48019.1 - 0.0024 17.6 0.0 0.0043 16.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EMG48019.1 - 0.0087 16.3 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain COesterase PF00135.23 EMG48019.1 - 0.016 13.9 0.0 0.27 9.8 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Abhydrolase_6 PF12697.2 EMG48019.1 - 0.024 14.5 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.7 EMG48019.1 - 0.18 11.0 0.0 8.4 5.6 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) ABC1 PF03109.11 EMG48020.1 - 2.6e-24 85.4 0.1 5.1e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 ABC1 family WD40 PF00400.27 EMG48021.1 - 4.6e-59 194.3 13.7 2.4e-07 30.3 0.0 10.5 10 0 0 10 10 10 10 WD domain, G-beta repeat Utp13 PF08625.6 EMG48021.1 - 3.8e-47 159.4 0.7 6.3e-47 158.7 0.5 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain eIF2A PF08662.6 EMG48021.1 - 0.0032 17.1 3.7 3.8 7.1 0.0 5.1 5 2 1 6 6 6 2 Eukaryotic translation initiation factor eIF2A CRF1 PF10380.4 EMG48022.1 - 1.3e-35 122.3 3.9 1.3e-35 122.3 2.7 4.1 3 1 0 3 3 3 1 Transcription factor CRF1 Ribonuclease_3 PF00636.21 EMG48023.1 - 1.4e-21 77.0 0.5 1.4e-20 73.8 0.0 2.8 3 0 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EMG48023.1 - 1.5e-19 70.2 3.8 2e-19 69.8 0.0 2.7 3 0 0 3 3 3 1 Ribonuclease-III-like dsrm PF00035.20 EMG48023.1 - 3.3e-15 56.4 0.3 2.8e-07 30.9 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif RE_Eco29kI PF09517.5 EMG48023.1 - 0.057 12.7 0.1 1.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Eco29kI restriction endonuclease AcetylCoA_hydro PF02550.10 EMG48025.1 - 1.5e-63 214.1 0.0 2.6e-63 213.3 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 EMG48025.1 - 3.3e-42 143.7 0.0 5.1e-42 143.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.18 EMG48025.1 - 0.11 11.5 0.0 0.53 9.4 0.0 2.2 3 0 0 3 3 3 0 Coenzyme A transferase SSF PF00474.12 EMG48026.1 - 3.2e-06 26.0 32.7 1.3e-05 24.0 21.8 2.5 1 1 1 2 2 2 1 Sodium:solute symporter family DUF2424 PF10340.4 EMG48027.1 - 5.1e-24 84.6 0.1 6.4e-24 84.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 EMG48027.1 - 1.7e-13 50.6 0.0 2.4e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMG48027.1 - 0.0028 17.4 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF4264 PF14084.1 EMG48027.1 - 0.082 12.2 0.5 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4264) COesterase PF00135.23 EMG48027.1 - 0.098 11.3 0.0 4.2 5.9 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family DUF2424 PF10340.4 EMG48028.1 - 1.3e-28 99.7 0.0 1.8e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 EMG48028.1 - 3e-14 53.0 0.0 5.6e-14 52.2 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMG48028.1 - 5.1e-05 23.0 0.0 7.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EMG48028.1 - 0.008 14.9 0.0 0.14 10.8 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.2 EMG48028.1 - 0.009 15.9 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EMG48028.1 - 0.017 15.3 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain NDK PF00334.14 EMG48030.1 - 5.5e-54 181.6 0.0 6.2e-54 181.4 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase WD40 PF00400.27 EMG48031.1 - 1.3e-16 59.6 13.9 1e-06 28.3 0.0 6.5 6 1 0 6 6 6 4 WD domain, G-beta repeat RabGAP-TBC PF00566.13 EMG48032.1 - 2.9e-14 53.0 13.4 2.9e-14 53.0 9.3 3.0 3 1 0 3 3 3 2 Rab-GTPase-TBC domain UPF0114 PF03350.11 EMG48032.1 - 0.023 14.6 0.2 0.085 12.7 0.1 1.9 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 Dopey_N PF04118.9 EMG48033.1 - 2.9e-111 371.1 0.4 2.9e-111 371.1 0.3 2.3 2 0 0 2 2 2 1 Dopey, N-terminal DUF4305 PF14146.1 EMG48033.1 - 0.11 12.2 0.6 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4305) UbiA PF01040.13 EMG48034.1 - 8.8e-23 80.8 15.8 1.9e-22 79.7 11.0 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family DUF1705 PF08019.7 EMG48034.1 - 0.15 11.5 0.2 0.15 11.5 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1705) MitMem_reg PF13012.1 EMG48035.1 - 4.9e-42 142.6 0.4 9.9e-42 141.6 0.3 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EMG48035.1 - 6.3e-27 93.5 0.0 1.2e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease FUSC-like PF12805.2 EMG48035.1 - 0.12 11.3 0.1 0.18 10.7 0.1 1.3 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS ATP_bind_1 PF03029.12 EMG48036.1 - 4.1e-67 226.1 0.1 5.2e-67 225.8 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein DUF3835 PF12927.2 EMG48037.1 - 1.1e-19 71.1 11.5 2.5e-17 63.5 1.8 6.9 6 2 1 7 7 7 2 Domain of unknown function (DUF3835) Prefoldin_3 PF13758.1 EMG48037.1 - 5.5e-05 22.8 3.4 5.5e-05 22.8 2.4 3.1 2 0 0 2 2 2 1 Prefoldin subunit PilJ PF13675.1 EMG48037.1 - 0.039 14.2 1.8 0.077 13.3 0.2 2.4 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term ACR_tran PF00873.14 EMG48037.1 - 4.6 4.5 8.5 7.6 3.7 5.9 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family NPV_P10 PF05531.7 EMG48038.1 - 7e-05 22.9 4.5 0.00086 19.5 0.4 2.2 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 EMG48038.1 - 0.0075 16.1 1.7 0.13 12.1 0.4 2.1 1 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.6 EMG48038.1 - 0.0078 16.0 7.9 0.19 11.5 0.4 2.6 1 1 1 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 CENP-F_leu_zip PF10473.4 EMG48038.1 - 0.016 15.1 2.2 0.016 15.1 1.5 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin PF00261.15 EMG48038.1 - 0.037 13.1 14.6 0.085 11.9 1.8 3.1 3 0 0 3 3 3 0 Tropomyosin Streptin-Immun PF11083.3 EMG48038.1 - 0.039 13.9 7.0 0.052 13.5 2.3 2.7 1 1 2 3 3 3 0 Lantibiotic streptin immunity protein Filament PF00038.16 EMG48038.1 - 0.04 13.3 12.9 0.026 13.9 2.7 2.0 1 1 1 2 2 2 0 Intermediate filament protein Reo_sigmaC PF04582.7 EMG48038.1 - 0.044 12.9 2.4 2 7.5 0.0 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF4407 PF14362.1 EMG48038.1 - 0.049 12.5 0.8 0.083 11.8 0.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Laminin_I PF06008.9 EMG48038.1 - 0.096 11.9 8.0 0.037 13.3 1.3 2.4 1 1 1 2 2 2 0 Laminin Domain I Spc7 PF08317.6 EMG48038.1 - 0.11 11.1 11.2 0.23 10.0 7.7 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein ALIX_LYPXL_bnd PF13949.1 EMG48038.1 - 0.13 11.1 13.1 0.89 8.4 9.1 2.2 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV HrpB7 PF09486.5 EMG48038.1 - 0.13 12.1 3.9 0.88 9.4 2.7 2.0 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) BLOC1_2 PF10046.4 EMG48038.1 - 0.14 12.3 7.5 0.44 10.7 0.6 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Apolipoprotein PF01442.13 EMG48038.1 - 0.23 10.9 8.6 0.19 11.2 0.4 2.2 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF1664 PF07889.7 EMG48038.1 - 0.25 11.1 5.4 1.9 8.2 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TBPIP PF07106.8 EMG48038.1 - 0.27 10.7 11.3 0.14 11.6 1.8 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fez1 PF06818.10 EMG48038.1 - 0.28 11.1 9.0 1.2 9.1 6.2 2.1 1 1 0 1 1 1 0 Fez1 Sec34 PF04136.10 EMG48038.1 - 0.29 10.8 4.4 0.98 9.0 2.9 1.9 1 1 1 2 2 2 0 Sec34-like family V_ATPase_I PF01496.14 EMG48038.1 - 0.3 8.9 12.1 0.17 9.6 2.6 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.7 EMG48038.1 - 0.3 10.8 7.6 1.4 8.6 3.1 2.1 1 1 1 2 2 2 0 Laminin Domain II IncA PF04156.9 EMG48038.1 - 0.34 10.4 13.6 0.64 9.5 2.7 2.1 1 1 1 2 2 2 0 IncA protein LLC1 PF14945.1 EMG48038.1 - 0.37 11.1 2.6 1.6 9.0 0.1 2.4 2 1 1 3 3 3 0 Normal lung function maintenance, Low in Lung Cancer 1 protein DUF3347 PF11827.3 EMG48038.1 - 0.38 10.7 3.7 0.6 10.0 2.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) PhaP_Bmeg PF09602.5 EMG48038.1 - 0.44 10.3 5.3 2.7 7.7 2.3 2.6 1 1 2 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF4446 PF14584.1 EMG48038.1 - 0.47 10.2 5.5 1.4 8.7 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Paramyx_P_V_C PF03210.8 EMG48038.1 - 0.63 9.9 4.1 4.3 7.1 0.3 2.5 1 1 1 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal SlyX PF04102.7 EMG48038.1 - 0.64 10.4 6.8 2.9 8.3 0.7 2.9 2 1 2 4 4 4 0 SlyX DUF730 PF05325.6 EMG48038.1 - 0.81 9.4 3.0 1.5 8.5 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF730) Phage_Mu_Gam PF07352.7 EMG48038.1 - 1.1 8.7 7.3 0.9 9.0 0.2 2.9 1 1 2 3 3 3 0 Bacteriophage Mu Gam like protein Histone_HNS PF00816.16 EMG48038.1 - 1.5 9.3 6.2 3.1 8.3 0.9 2.5 1 1 2 3 3 2 0 H-NS histone family LUC7 PF03194.10 EMG48038.1 - 2.3 7.6 7.9 12 5.3 5.4 1.9 1 1 0 1 1 1 0 LUC7 N_terminus APG6 PF04111.7 EMG48038.1 - 2.3 7.1 13.1 1.1 8.2 2.9 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Tup_N PF08581.5 EMG48038.1 - 3.2 8.0 10.2 9.7 6.4 2.0 3.1 2 1 1 3 3 3 0 Tup N-terminal Fzo_mitofusin PF04799.8 EMG48038.1 - 4.4 6.6 9.7 1.9 7.8 1.1 2.1 2 0 0 2 2 2 0 fzo-like conserved region Zein-binding PF04576.10 EMG48038.1 - 7.3 6.7 8.7 6.4 6.9 1.6 3.3 2 2 0 2 2 2 0 Zein-binding TMF_DNA_bd PF12329.3 EMG48038.1 - 9.1 6.1 13.2 1.8 8.4 1.7 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding GST_N PF02798.15 EMG48039.1 - 1.5e-11 44.3 0.0 7.2e-11 42.1 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMG48039.1 - 3.2e-11 43.0 0.0 5.2e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMG48039.1 - 1.3e-10 41.3 0.0 2.1e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMG48039.1 - 3.1e-09 36.6 0.0 5.9e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMG48039.1 - 1.3e-06 28.1 0.0 2.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMG48039.1 - 0.00076 19.9 0.1 0.001 19.4 0.0 1.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3427 PF11907.3 EMG48039.1 - 0.025 13.5 0.1 0.031 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3427) Pkinase PF00069.20 EMG48040.1 - 2.5e-73 246.4 0.0 2.5e-73 246.4 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG48040.1 - 5.8e-36 123.8 0.0 2.6e-35 121.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG48040.1 - 0.0039 16.2 0.0 0.012 14.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMG48040.1 - 0.035 13.8 2.5 0.041 13.5 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Snf7 PF03357.16 EMG48041.1 - 4.2e-19 68.5 15.6 5.1e-19 68.2 10.8 1.2 1 0 0 1 1 1 1 Snf7 Latrotoxin_C PF15658.1 EMG48041.1 - 0.0014 18.4 1.5 0.049 13.4 0.0 2.6 1 1 1 2 2 2 1 Latrotoxin C-terminal domain Ist1 PF03398.9 EMG48041.1 - 0.016 14.6 6.7 0.033 13.6 4.7 1.5 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Polysacc_synt_4 PF04669.8 EMG48041.1 - 0.031 13.6 0.1 0.05 12.9 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis Prominin PF05478.6 EMG48041.1 - 0.044 11.3 10.1 0.049 11.1 7.0 1.1 1 0 0 1 1 1 0 Prominin GAD PF02938.9 EMG48041.1 - 0.073 13.2 1.8 0.37 10.9 0.0 2.4 2 1 0 2 2 2 0 GAD domain Cytochrom_B562 PF07361.6 EMG48041.1 - 0.22 11.9 8.1 0.15 12.4 1.0 2.4 2 0 0 2 2 2 0 Cytochrome b562 GvpK PF05121.7 EMG48041.1 - 0.36 10.6 6.4 0.87 9.4 0.1 3.5 3 1 1 4 4 4 0 Gas vesicle protein K TPR_MLP1_2 PF07926.7 EMG48041.1 - 1 9.0 11.5 0.77 9.5 3.1 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Hyphal_reg_CWP PF11765.3 EMG48043.1 - 3.8e-137 456.5 19.0 4.3e-137 456.3 13.2 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal DUF995 PF06191.7 EMG48043.1 - 0.024 14.0 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF995) Med15 PF09606.5 EMG48044.1 - 3.1 5.8 126.2 2.1 6.4 12.4 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal PhzC-PhzF PF02567.11 EMG48046.1 - 2.5e-68 230.3 0.0 2.8e-68 230.1 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.6 EMG48046.1 - 4.5e-08 32.3 0.0 1e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 Proline racemase DUF3818 PF12825.2 EMG48047.1 - 1e-104 349.8 19.8 4.4e-53 180.1 0.2 2.5 2 1 1 3 3 3 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EMG48047.1 - 2e-44 150.5 4.2 5e-44 149.2 2.9 1.8 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EMG48047.1 - 5.3e-09 35.8 5.2 8.7e-09 35.1 1.6 3.0 2 0 0 2 2 2 1 PX domain Alpha-amylase_C PF02806.13 EMG48048.1 - 4.4e-27 94.0 0.6 7.6e-25 86.8 0.0 3.1 2 1 1 3 3 3 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EMG48048.1 - 1.2e-16 61.0 0.9 9e-15 54.8 0.5 2.6 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EMG48048.1 - 1.1e-14 54.1 0.1 3.2e-14 52.7 0.1 1.9 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Sec1 PF00995.18 EMG48049.1 - 8.7e-67 226.0 1.7 9.6e-67 225.8 1.2 1.0 1 0 0 1 1 1 1 Sec1 family DUF3439 PF11921.3 EMG48050.1 - 0.021 14.5 1.0 0.03 14.0 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Shisa PF13908.1 EMG48050.1 - 0.067 13.3 0.6 0.084 13.0 0.4 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator SoxE PF06525.6 EMG48050.1 - 1.2 8.4 4.7 1.4 8.1 3.3 1.2 1 0 0 1 1 1 0 Sulfocyanin (SoxE) Mito_fiss_reg PF05308.6 EMG48050.1 - 8.5 5.6 7.9 10 5.3 5.5 1.3 1 1 0 1 1 1 0 Mitochondrial fission regulator Actin PF00022.14 EMG48051.1 - 3e-100 335.3 0.0 3.5e-100 335.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EMG48051.1 - 0.0008 18.0 0.0 0.09 11.3 0.0 2.6 2 1 0 2 2 2 2 MreB/Mbl protein KH_1 PF00013.24 EMG48052.1 - 2.2e-37 126.4 1.7 6.3e-14 51.3 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EMG48052.1 - 1.9e-22 78.4 10.0 5.9e-08 32.1 0.2 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EMG48052.1 - 1.3e-11 43.9 3.6 0.00078 19.0 0.0 4.1 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 EMG48052.1 - 3.1e-08 33.0 4.2 0.023 14.2 0.0 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EMG48052.1 - 0.00013 21.7 1.0 1.7 8.5 0.0 3.4 3 0 0 3 3 3 3 NusA-like KH domain Sec1 PF00995.18 EMG48054.1 - 1.2e-48 166.2 4.2 1.3e-48 166.0 2.9 1.0 1 0 0 1 1 1 1 Sec1 family Syntaxin-18_N PF10496.4 EMG48054.1 - 0.066 13.0 1.1 0.14 11.9 0.7 1.6 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus DUF1474 PF07342.6 EMG48054.1 - 1.2 9.4 4.1 1.1 9.5 0.2 2.5 2 1 0 3 3 3 0 Protein of unknown function (DUF1474) RNase_H PF00075.19 EMG48055.1 - 2e-24 86.4 2.1 3.2e-24 85.7 1.4 1.3 1 0 0 1 1 1 1 RNase H SF-assemblin PF06705.6 EMG48055.1 - 0.038 13.1 0.3 0.049 12.7 0.2 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin PhzC-PhzF PF02567.11 EMG48056.1 - 3.3e-60 203.6 0.0 3.7e-60 203.5 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.6 EMG48056.1 - 1.2e-08 34.1 0.0 2.2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Proline racemase zinc_ribbon_5 PF13719.1 EMG48057.1 - 0.35 10.4 4.9 0.72 9.4 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EMG48057.1 - 0.41 10.3 4.9 0.86 9.3 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain LRR_8 PF13855.1 EMG48058.1 - 0.00012 21.7 17.0 0.18 11.6 0.1 7.7 8 0 0 8 8 8 3 Leucine rich repeat LRR_4 PF12799.2 EMG48058.1 - 0.001 18.6 0.0 0.001 18.6 0.0 8.5 7 2 0 7 7 7 2 Leucine Rich repeats (2 copies) Pyr_redox_2 PF07992.9 EMG48059.1 - 3.3e-10 40.2 0.4 2.1e-09 37.5 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMG48059.1 - 0.00097 19.2 0.6 0.0026 17.8 0.4 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ATP_transf PF09830.4 EMG48060.1 - 7.8e-21 73.6 0.0 1.5e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 EMG48060.1 - 0.00012 22.5 0.0 0.0003 21.2 0.0 1.6 1 0 0 1 1 1 1 HIT domain AMP-binding PF00501.23 EMG48062.1 - 1.2e-45 155.7 0.0 8.6e-25 86.9 0.0 4.1 2 2 0 2 2 2 2 AMP-binding enzyme PPR PF01535.15 EMG48063.1 - 2.5e-10 39.6 3.8 0.02 14.8 0.0 5.6 5 1 0 5 5 5 4 PPR repeat PPR_2 PF13041.1 EMG48063.1 - 1e-09 38.2 7.1 0.0098 15.8 0.3 4.9 3 1 2 5 5 5 4 PPR repeat family PPR_3 PF13812.1 EMG48063.1 - 1.4e-07 31.1 0.6 0.029 14.6 0.0 5.6 6 0 0 6 6 6 1 Pentatricopeptide repeat domain Rapsyn_N PF10579.4 EMG48063.1 - 0.0085 15.8 0.4 0.67 9.8 0.0 3.9 5 0 0 5 5 5 1 Rapsyn N-terminal myristoylation and linker region ATP13 PF12921.2 EMG48063.1 - 0.025 13.9 0.2 4.9 6.5 0.0 2.8 1 1 1 2 2 2 0 Mitochondrial ATPase expression tRNA-synt_1 PF00133.17 EMG48064.1 - 2.8e-53 180.8 0.4 2.4e-17 62.2 0.2 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 EMG48064.1 - 3.5e-43 147.0 0.0 6.8e-43 146.1 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EMG48064.1 - 4.1e-28 98.1 0.9 9.1e-23 80.5 0.0 4.4 4 1 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EMG48064.1 - 2.3e-12 46.9 0.1 2.3e-12 46.9 0.1 2.0 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 EMG48064.1 - 0.0073 15.1 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 EMG48064.1 - 0.07 12.2 0.0 1.2 8.2 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1c PF00749.16 EMG48064.1 - 0.079 11.6 0.2 9.6 4.7 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain CRAL_TRIO PF00650.15 EMG48066.1 - 3e-41 140.5 0.1 7.1e-41 139.3 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EMG48066.1 - 1.3e-10 41.3 0.0 2.5e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMG48066.1 - 6.3e-10 39.0 0.1 2.6e-09 37.0 0.1 2.1 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Mito_carr PF00153.22 EMG48067.1 - 7.2e-61 201.9 1.2 1.4e-19 69.6 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein UCR_14kD PF02271.11 EMG48068.1 - 3.7e-42 142.3 0.4 4.3e-42 142.1 0.3 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Pyr_redox_2 PF07992.9 EMG48069.1 - 2.5e-14 53.6 0.0 3.3e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 EMG48070.1 - 5.8e-38 130.5 36.5 5.8e-38 130.5 25.3 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG48070.1 - 6.9e-12 44.6 29.9 6.4e-11 41.4 20.6 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter Asp PF00026.18 EMG48071.1 - 1.2e-89 300.6 10.6 1.6e-89 300.3 7.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMG48071.1 - 1.9e-08 34.4 1.4 4.7e-08 33.1 0.4 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMG48071.1 - 1.3e-06 28.8 5.3 0.069 13.6 0.9 4.4 2 2 1 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EMG48071.1 - 0.0011 18.5 0.0 0.024 14.1 0.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EMG48071.1 - 0.039 13.7 0.1 0.4 10.5 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Fungal_trans_2 PF11951.3 EMG48072.1 - 1e-33 116.4 1.3 1.5e-33 115.9 0.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG48072.1 - 3.7e-08 33.1 10.1 6.4e-08 32.3 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SF3a60_bindingd PF12108.3 EMG48072.1 - 0.36 10.4 3.5 0.84 9.2 1.1 2.3 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain Ribosomal_L10 PF00466.15 EMG48073.1 - 4.1e-16 58.7 0.1 7.1e-16 57.9 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L10 CRT10 PF08728.5 EMG48074.1 - 2.5e-150 501.8 14.5 2e-107 360.0 4.8 2.4 1 1 1 2 2 2 2 CRT10 GAF_2 PF13185.1 EMG48075.1 - 3.4e-08 34.0 0.0 4e-08 33.8 0.0 1.3 1 1 0 1 1 1 1 GAF domain GAF PF01590.21 EMG48075.1 - 0.00019 21.5 0.0 0.00023 21.2 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EMG48075.1 - 0.00054 20.0 0.0 0.00095 19.2 0.0 1.6 1 1 0 1 1 1 1 GAF domain LicD PF04991.8 EMG48077.1 - 5.7e-44 150.6 2.2 5.7e-44 150.6 1.5 4.6 4 1 1 5 5 5 1 LicD family PAT1 PF09770.4 EMG48078.1 - 0.00017 20.0 56.5 0.00017 20.0 39.2 2.1 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 DUF342 PF03961.8 EMG48078.1 - 0.26 9.6 17.0 0.39 9.0 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Rogdi_lz PF10259.4 EMG48079.1 - 2.9e-59 200.4 1.8 3.3e-59 200.2 1.2 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Phage-tail_1 PF09097.5 EMG48079.1 - 0.043 13.3 0.3 0.08 12.5 0.2 1.5 1 0 0 1 1 1 0 Baseplate structural protein, domain 1 Peptidase_M16 PF00675.15 EMG48080.1 - 7.8e-44 149.0 1.3 2.6e-42 144.1 0.2 3.2 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EMG48080.1 - 9.7e-32 110.1 0.2 1.4e-20 73.7 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain FTHFS PF01268.14 EMG48081.1 - 4.4e-260 863.4 0.1 5.3e-260 863.1 0.1 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EMG48081.1 - 4.6e-64 214.3 0.5 1.3e-63 212.9 0.1 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EMG48081.1 - 1.1e-36 125.4 2.0 2.3e-36 124.3 1.4 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 2_5_RNA_ligase2 PF13563.1 EMG48081.1 - 0.0021 17.8 0.0 0.0049 16.6 0.0 1.5 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily GTP_EFTU PF00009.22 EMG48081.1 - 0.089 12.2 0.2 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ADH_N PF08240.7 EMG48082.1 - 7.5e-24 83.6 0.8 1.2e-23 82.9 0.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMG48082.1 - 2.4e-18 65.9 0.0 3.6e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EMG48082.1 - 1.3e-08 34.1 0.0 2.4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EMG48082.1 - 0.00011 21.7 0.1 0.00037 20.1 0.1 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 EMG48082.1 - 0.002 17.7 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_2 PF03446.10 EMG48082.1 - 0.007 16.2 0.0 0.018 14.9 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EMG48082.1 - 0.023 14.8 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RNase_H PF00075.19 EMG48083.1 - 1.4e-24 86.9 0.1 1.9e-24 86.5 0.1 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 EMG48083.1 - 2.1e-11 43.6 0.6 4.5e-11 42.5 0.5 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin CH PF00307.26 EMG48085.1 - 2.3e-75 249.6 0.1 7.6e-22 77.4 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EMG48085.1 - 7.3e-11 41.5 0.1 0.32 10.6 0.0 4.5 4 0 0 4 4 4 4 CAMSAP CH domain EF-hand_7 PF13499.1 EMG48085.1 - 4.8e-05 23.4 1.9 0.00026 21.0 0.2 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EMG48085.1 - 0.00027 20.0 0.4 0.17 11.2 0.0 3.6 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 EMG48085.1 - 0.0068 16.2 0.2 9.4 6.4 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain PHD PF00628.24 EMG48086.1 - 2e-09 36.9 2.4 2e-09 36.9 1.7 2.1 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EMG48086.1 - 0.02 14.1 4.2 0.036 13.3 2.9 1.4 1 0 0 1 1 1 0 PHD-finger DNA_pol_B_thumb PF14791.1 EMG48086.1 - 0.19 11.4 2.3 0.18 11.5 0.2 2.1 2 0 0 2 2 2 0 DNA polymerase beta thumb T2SM PF04612.7 EMG48086.1 - 1.6 8.5 9.0 3.7 7.3 6.3 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M CPSase_L_D2 PF02786.12 EMG48088.1 - 1.5e-115 383.8 0.7 8.4e-83 276.8 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain OTCace_N PF02729.16 EMG48088.1 - 1.3e-46 157.8 0.0 3.3e-46 156.4 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_sm_chain PF00988.17 EMG48088.1 - 1.6e-46 157.0 0.0 3.8e-46 155.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EMG48088.1 - 1.4e-44 151.8 0.0 3.1e-44 150.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_chain PF00289.17 EMG48088.1 - 2.4e-42 143.4 0.0 1.5e-21 76.5 0.0 3.1 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 EMG48088.1 - 8.8e-41 138.5 0.0 2e-40 137.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EMG48088.1 - 5.4e-35 120.7 0.1 9.7e-23 80.8 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 EMG48088.1 - 4.4e-33 114.3 0.5 1.3e-32 112.8 0.1 2.1 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 EMG48088.1 - 4.3e-22 78.2 0.0 7.2e-12 44.6 0.0 3.5 3 0 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 EMG48088.1 - 1.7e-20 72.7 0.0 1.6e-19 69.5 0.0 2.8 3 0 0 3 3 3 1 MGS-like domain Dala_Dala_lig_C PF07478.8 EMG48088.1 - 3e-16 59.4 1.2 3.7e-09 36.2 0.1 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EMG48088.1 - 1.5e-15 56.9 0.1 1.6e-07 30.8 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.9 EMG48088.1 - 6.9e-07 29.2 0.7 0.012 15.5 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EMG48088.1 - 8.6e-07 28.6 0.0 2.4e-05 23.8 0.0 2.5 1 1 0 1 1 1 1 Peptidase C26 RimK PF08443.6 EMG48088.1 - 3.7e-06 26.5 0.1 0.00014 21.3 0.0 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain DUF947 PF06102.7 EMG48089.1 - 9.3e-50 168.7 28.2 1.9e-49 167.6 19.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF947) Rhodanese PF00581.15 EMG48090.1 - 1e-16 61.3 0.0 1.7e-16 60.5 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain ATP_bind_3 PF01171.15 EMG48091.1 - 2.3e-46 157.6 0.1 3.1e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 PP-loop family Asn_synthase PF00733.16 EMG48091.1 - 7.7e-05 22.3 0.0 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EMG48091.1 - 0.0028 16.9 0.0 0.037 13.3 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA-synt_1 PF00133.17 EMG48092.1 - 4.4e-227 754.8 0.2 1.1e-226 753.5 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EMG48092.1 - 2.1e-25 89.2 0.6 5.5e-25 87.9 0.1 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EMG48092.1 - 4.1e-19 68.5 2.1 2.6e-07 29.6 0.1 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EMG48092.1 - 0.0089 15.1 0.0 0.027 13.6 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain PASTA PF03793.14 EMG48092.1 - 0.014 14.9 0.2 0.67 9.6 0.0 2.6 2 0 0 2 2 2 0 PASTA domain tRNA-synt_1_2 PF13603.1 EMG48092.1 - 0.083 12.1 0.1 0.23 10.7 0.1 1.8 1 1 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 WD40 PF00400.27 EMG48093.1 - 3.3e-25 86.9 29.5 5.1e-07 29.3 0.1 9.3 9 1 0 9 9 9 8 WD domain, G-beta repeat CPSF_A PF03178.10 EMG48093.1 - 0.0011 18.0 6.2 0.026 13.6 0.0 3.6 3 1 1 4 4 4 2 CPSF A subunit region DUF4476 PF14771.1 EMG48093.1 - 0.024 14.6 0.2 2.7 8.0 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4476) Aminotran_1_2 PF00155.16 EMG48094.1 - 6.6e-37 127.3 0.0 9.1e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II zf-C2H2 PF00096.21 EMG48095.1 - 3.2e-12 46.0 16.8 8.1e-06 25.8 1.2 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMG48095.1 - 5e-12 45.4 14.2 4.3e-08 33.0 1.7 4.7 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMG48095.1 - 2.9e-10 39.7 13.0 0.0011 19.1 0.5 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMG48095.1 - 5.3e-07 29.5 9.2 0.0004 20.4 0.5 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMG48095.1 - 0.0055 16.8 7.8 0.028 14.6 0.4 3.7 3 0 0 3 3 3 1 Zinc-finger of C2H2 type PAXIP1_C PF15364.1 EMG48095.1 - 0.038 13.9 2.6 0.25 11.2 1.4 2.2 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein C1_4 PF07975.7 EMG48095.1 - 0.87 9.6 5.7 11 6.1 3.3 2.8 2 1 1 3 3 3 0 TFIIH C1-like domain zf-C2H2_6 PF13912.1 EMG48095.1 - 1.1 9.2 7.8 0.98 9.4 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EMG48095.1 - 6.7 7.1 10.5 1.1 9.6 1.4 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain LRR_4 PF12799.2 EMG48096.1 - 0.1 12.2 0.1 0.1 12.2 0.1 5.3 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) F-box PF00646.28 EMG48096.1 - 0.27 10.9 3.0 1 9.0 0.3 3.0 2 1 0 2 2 2 0 F-box domain LRR_7 PF13504.1 EMG48096.1 - 0.28 11.5 14.8 15 6.3 0.3 6.8 7 0 0 7 7 7 0 Leucine rich repeat LRR_6 PF13516.1 EMG48096.1 - 0.41 10.8 17.2 5.1 7.4 0.0 7.0 6 1 1 7 7 7 0 Leucine Rich repeat LRR_1 PF00560.28 EMG48096.1 - 1.9 8.8 22.9 2.4 8.5 0.5 7.5 7 1 1 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.1 EMG48096.1 - 6.1 6.6 20.1 1 9.1 2.4 5.0 3 2 2 5 5 5 0 Leucine rich repeat DUF3074 PF11274.3 EMG48097.1 - 2.4e-27 95.7 0.1 3.3e-27 95.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) FAD_binding_3 PF01494.14 EMG48098.1 - 2.9e-80 270.0 0.0 1.9e-77 260.7 0.0 2.5 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EMG48098.1 - 8.5e-50 168.6 0.0 2.2e-49 167.3 0.0 1.7 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 EMG48098.1 - 0.00031 19.3 0.0 0.0017 16.9 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EMG48098.1 - 0.0038 16.3 0.0 0.0066 15.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EMG48098.1 - 0.0082 15.0 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMG48098.1 - 0.013 15.3 0.0 0.032 14.0 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMG48098.1 - 0.016 14.0 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EMG48098.1 - 0.037 13.5 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 EMG48098.1 - 0.038 13.0 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMG48098.1 - 0.069 13.1 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMG48098.1 - 0.11 11.3 0.0 0.23 10.3 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EMG48098.1 - 0.12 10.9 0.0 0.19 10.3 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase ThiF PF00899.16 EMG48098.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.7 EMG48098.1 - 0.19 10.6 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein TrkH PF02386.11 EMG48099.1 - 1.2e-133 445.1 16.4 2.9e-131 437.2 7.8 2.2 2 0 0 2 2 2 2 Cation transport protein Brix PF04427.13 EMG48100.1 - 4.5e-33 114.5 0.7 6.3e-33 114.0 0.5 1.2 1 0 0 1 1 1 1 Brix domain RNase_E_G PF10150.4 EMG48100.1 - 0.13 11.4 0.4 0.17 11.0 0.3 1.1 1 0 0 1 1 1 0 Ribonuclease E/G family NAD_binding_6 PF08030.7 EMG48101.1 - 9.3e-27 93.8 0.1 1.4e-26 93.2 0.1 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMG48101.1 - 3.8e-26 90.9 0.1 9.6e-26 89.7 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 EMG48101.1 - 9.3e-20 70.9 12.3 9.3e-20 70.9 8.5 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component Peptidase_S64 PF08192.6 EMG48102.1 - 1.9e-266 885.8 16.8 2.3e-266 885.6 11.6 1.1 1 0 0 1 1 1 1 Peptidase family S64 Eaf7 PF07904.8 EMG48102.1 - 0.14 12.1 4.2 2.3 8.2 0.1 3.6 3 0 0 3 3 3 0 Chromatin modification-related protein EAF7 MFS_1 PF07690.11 EMG48103.1 - 5.5e-37 127.3 36.7 5.5e-37 127.3 25.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily LRR_8 PF13855.1 EMG48104.1 - 1e-05 25.1 0.2 1.9e-05 24.2 0.1 1.6 1 1 0 1 1 1 1 Leucine rich repeat LRR_6 PF13516.1 EMG48104.1 - 1.1e-05 24.9 0.5 0.058 13.4 0.1 2.7 2 0 0 2 2 2 2 Leucine Rich repeat LRR_4 PF12799.2 EMG48104.1 - 0.0001 21.8 0.7 0.013 15.0 0.1 2.7 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMG48104.1 - 0.0054 16.5 1.1 0.16 12.0 0.1 3.1 3 2 0 3 3 3 1 Leucine Rich Repeat LRR_7 PF13504.1 EMG48104.1 - 0.13 12.5 1.2 1.8 9.1 0.1 3.0 3 0 0 3 3 3 0 Leucine rich repeat EOS1 PF12326.3 EMG48106.1 - 1.5e-16 60.3 1.4 2.5e-16 59.6 1.0 1.3 1 0 0 1 1 1 1 N-glycosylation protein DUF663 PF04950.7 EMG48107.1 - 6.9e-92 307.5 0.0 1.2e-91 306.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EMG48107.1 - 4.3e-22 77.4 0.0 1e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain APG6 PF04111.7 EMG48107.1 - 1 8.3 6.4 2.7 6.9 4.4 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 Flocculin_t3 PF13928.1 EMG48108.1 - 4.3e-05 23.5 38.4 0.0011 19.1 11.5 11.2 3 2 5 8 8 8 4 Flocculin type 3 repeat DUF732 PF05305.9 EMG48108.1 - 5.2 7.2 9.8 1.2 9.2 0.4 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF732) Tropomyosin_1 PF12718.2 EMG48109.1 - 3.9e-46 156.4 43.8 5e-46 156.0 30.3 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EMG48109.1 - 2.5e-07 30.0 41.6 0.00013 21.1 12.9 2.0 1 1 1 2 2 2 2 Tropomyosin GAS PF13851.1 EMG48109.1 - 6.4e-06 25.4 40.5 7.1e-06 25.3 28.1 1.0 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Mod_r PF07200.8 EMG48109.1 - 3.9e-05 23.6 33.4 0.0014 18.6 17.1 2.6 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein CENP-F_leu_zip PF10473.4 EMG48109.1 - 0.0002 21.2 11.9 0.0002 21.2 8.2 2.9 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.7 EMG48109.1 - 0.00029 20.6 25.0 0.024 14.3 7.4 2.1 1 1 1 2 2 2 2 Laminin Domain II APG6 PF04111.7 EMG48109.1 - 0.0013 17.8 43.6 0.099 11.6 15.7 2.0 1 1 1 2 2 2 2 Autophagy protein Apg6 Filament PF00038.16 EMG48109.1 - 0.0015 18.0 33.5 0.014 14.8 23.2 2.0 1 1 0 1 1 1 1 Intermediate filament protein TMF_DNA_bd PF12329.3 EMG48109.1 - 0.0025 17.5 18.9 0.0025 17.5 13.1 3.3 1 1 3 4 4 4 1 TATA element modulatory factor 1 DNA binding Myosin_tail_1 PF01576.14 EMG48109.1 - 0.003 15.3 40.3 0.0035 15.1 28.0 1.0 1 0 0 1 1 1 1 Myosin tail DUF1220 PF06758.8 EMG48109.1 - 0.0099 15.6 1.2 0.022 14.5 0.9 1.6 1 0 0 1 1 1 1 Repeat of unknown function (DUF1220) KLRAQ PF10205.4 EMG48109.1 - 0.012 15.6 26.2 0.36 10.8 5.2 2.2 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF3287 PF11690.3 EMG48109.1 - 0.013 15.5 3.3 0.013 15.5 2.3 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3287) Reo_sigmaC PF04582.7 EMG48109.1 - 0.014 14.5 8.5 0.014 14.5 1.9 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Prefoldin_2 PF01920.15 EMG48109.1 - 0.025 14.3 42.6 0.11 12.2 20.4 3.6 1 1 1 2 2 2 0 Prefoldin subunit ERM PF00769.14 EMG48109.1 - 0.026 14.0 40.4 0.054 13.0 14.6 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family WXG100 PF06013.7 EMG48109.1 - 0.034 14.1 16.7 0.64 10.0 0.3 3.7 2 1 1 3 3 3 0 Proteins of 100 residues with WXG bZIP_1 PF00170.16 EMG48109.1 - 0.042 13.8 39.5 0.042 13.7 2.1 5.2 2 1 2 4 4 4 0 bZIP transcription factor IncA PF04156.9 EMG48109.1 - 0.047 13.2 38.9 0.054 13.0 22.6 2.1 1 1 1 2 2 2 0 IncA protein ADIP PF11559.3 EMG48109.1 - 0.049 13.5 37.9 0.43 10.4 9.8 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Nup54 PF13874.1 EMG48109.1 - 0.051 13.2 24.2 0.27 10.9 6.6 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Prefoldin PF02996.12 EMG48109.1 - 0.056 13.0 36.0 0.14 11.8 2.2 4.0 1 1 3 4 4 4 0 Prefoldin subunit FliD_C PF07195.7 EMG48109.1 - 0.1 11.9 24.6 0.77 9.0 10.8 2.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus ATG16 PF08614.6 EMG48109.1 - 0.1 12.4 38.0 0.33 10.7 14.3 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.7 EMG48109.1 - 0.1 12.8 17.5 0.17 12.1 0.4 3.7 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein MIS13 PF08202.6 EMG48109.1 - 0.1 11.6 33.0 2.5 7.0 9.3 2.2 1 1 1 2 2 2 0 Mis12-Mtw1 protein family DUF2959 PF11172.3 EMG48109.1 - 0.1 12.3 18.1 0.35 10.5 4.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2959) DUF342 PF03961.8 EMG48109.1 - 0.11 10.8 33.0 0.24 9.7 11.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF3450 PF11932.3 EMG48109.1 - 0.11 11.7 28.3 0.15 11.3 7.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Mago_nashi PF02792.9 EMG48109.1 - 0.14 11.8 6.0 0.087 12.5 2.9 1.6 1 1 0 1 1 1 0 Mago nashi protein AAA_13 PF13166.1 EMG48109.1 - 0.16 10.3 33.9 0.21 10.0 23.5 1.2 1 0 0 1 1 1 0 AAA domain EzrA PF06160.7 EMG48109.1 - 0.19 9.8 30.0 0.28 9.3 8.8 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA PspA_IM30 PF04012.7 EMG48109.1 - 0.21 10.9 30.0 0.032 13.5 6.9 2.8 1 1 1 2 2 2 0 PspA/IM30 family Spc7 PF08317.6 EMG48109.1 - 0.24 10.0 37.2 0.034 12.8 17.1 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein AAA_27 PF13514.1 EMG48109.1 - 0.28 8.8 29.2 1.1 6.9 20.3 1.7 1 1 0 1 1 1 0 AAA domain DUF3584 PF12128.3 EMG48109.1 - 0.3 8.3 32.1 0.42 7.8 22.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Striatin PF08232.7 EMG48109.1 - 0.3 11.3 28.9 42 4.4 19.9 2.1 1 1 0 1 1 1 0 Striatin family HisKA_3 PF07730.8 EMG48109.1 - 0.31 11.4 10.7 7.1 7.0 0.2 3.8 1 1 2 3 3 3 0 Histidine kinase KxDL PF10241.4 EMG48109.1 - 0.31 10.9 15.2 0.64 9.9 4.6 3.1 1 1 2 3 3 3 0 Uncharacterized conserved protein TBPIP PF07106.8 EMG48109.1 - 0.36 10.3 37.8 3.2 7.2 12.1 2.7 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Taxilin PF09728.4 EMG48109.1 - 0.37 9.8 37.3 1.4 7.9 25.8 2.1 1 1 0 1 1 1 0 Myosin-like coiled-coil protein DUF972 PF06156.8 EMG48109.1 - 0.4 11.0 33.2 14 6.0 1.9 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4201 PF13870.1 EMG48109.1 - 0.42 10.0 35.0 2.3 7.6 0.8 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF724 PF05266.9 EMG48109.1 - 0.47 10.0 35.0 0.75 9.3 10.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Fib_alpha PF08702.5 EMG48109.1 - 0.51 10.4 24.7 0.52 10.4 5.9 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.4 EMG48109.1 - 0.52 10.4 32.7 1.8 8.7 6.8 3.6 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Adeno_PIX PF03955.9 EMG48109.1 - 0.62 10.5 18.0 4.5 7.8 1.4 3.3 1 1 2 3 3 3 0 Adenovirus hexon-associated protein (IX) Mnd1 PF03962.10 EMG48109.1 - 0.66 9.6 36.7 1.6 8.3 11.5 2.1 1 1 1 2 2 2 0 Mnd1 family bZIP_2 PF07716.10 EMG48109.1 - 0.72 9.7 35.1 0.4 10.5 2.2 5.2 2 2 3 5 5 5 0 Basic region leucine zipper Flagellin_N PF00669.15 EMG48109.1 - 0.79 9.5 8.8 2.7 7.7 0.7 2.3 1 1 2 3 3 3 0 Bacterial flagellin N-terminal helical region Snapin_Pallidin PF14712.1 EMG48109.1 - 0.85 9.9 27.2 8.2 6.8 7.5 3.6 1 1 2 3 3 3 0 Snapin/Pallidin tRNA_lig_kinase PF08303.6 EMG48109.1 - 0.89 9.4 5.3 0.93 9.3 2.9 1.6 1 1 0 1 1 1 0 tRNA ligase kinase domain DUF1311 PF07007.7 EMG48109.1 - 0.93 9.6 15.9 0.39 10.8 2.2 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF1311) DUF948 PF06103.6 EMG48109.1 - 0.94 9.3 19.2 0.36 10.7 2.2 3.2 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF4200 PF13863.1 EMG48109.1 - 0.97 9.3 41.2 3.1 7.7 14.7 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) FlaC_arch PF05377.6 EMG48109.1 - 1 9.2 30.6 1.2 9.1 1.2 4.9 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Lectin_N PF03954.9 EMG48109.1 - 1 8.7 14.4 0.32 10.4 3.7 2.7 1 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Ax_dynein_light PF10211.4 EMG48109.1 - 1.1 9.1 39.2 0.52 10.1 7.6 3.1 1 1 2 3 3 3 0 Axonemal dynein light chain IZUMO PF15005.1 EMG48109.1 - 1.1 9.3 12.5 1 9.3 5.4 2.1 1 1 1 2 2 2 0 Izumo sperm-egg fusion TPR_MLP1_2 PF07926.7 EMG48109.1 - 1.1 9.0 43.9 0.14 11.9 15.0 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3340 PF11818.3 EMG48109.1 - 1.1 9.1 30.6 2.1 8.2 9.8 2.2 1 1 1 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) BRE1 PF08647.6 EMG48109.1 - 1.2 9.1 37.5 0.18 11.7 9.1 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Sec20 PF03908.8 EMG48109.1 - 1.3 8.8 13.5 0.36 10.5 4.4 2.8 1 1 2 3 3 3 0 Sec20 MutS_III PF05192.13 EMG48109.1 - 1.5 8.5 7.6 2.3 7.9 5.3 1.4 1 0 0 1 1 1 0 MutS domain III DUF4140 PF13600.1 EMG48109.1 - 1.6 9.2 25.1 1.2 9.6 4.1 3.3 1 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) CCDC155 PF14662.1 EMG48109.1 - 1.7 8.2 40.1 0.74 9.3 11.0 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Laminin_I PF06008.9 EMG48109.1 - 1.8 7.8 30.5 0.19 11.0 7.5 2.2 1 1 1 2 2 2 0 Laminin Domain I Kinetocho_Slk19 PF12709.2 EMG48109.1 - 1.8 8.6 35.4 8.3 6.5 2.3 4.0 1 1 3 4 4 4 0 Central kinetochore-associated DUF904 PF06005.7 EMG48109.1 - 2 8.7 47.3 1.4 9.2 3.6 4.0 2 1 1 3 3 2 0 Protein of unknown function (DUF904) MbeD_MobD PF04899.7 EMG48109.1 - 2 8.3 11.9 5.6 6.9 1.1 3.0 2 1 1 3 3 3 0 MbeD/MobD like DUF3086 PF11285.3 EMG48109.1 - 2.3 6.9 16.6 0.77 8.5 8.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) T2SM PF04612.7 EMG48109.1 - 2.4 7.9 10.8 1.6 8.5 1.8 2.8 1 1 2 3 3 3 0 Type II secretion system (T2SS), protein M DUF745 PF05335.8 EMG48109.1 - 2.5 7.5 23.9 3.1 7.2 5.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF745) Fmp27_WPPW PF10359.4 EMG48109.1 - 2.7 6.2 29.7 0.69 8.2 11.0 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Seryl_tRNA_N PF02403.17 EMG48109.1 - 2.9 7.9 36.7 37 4.4 9.8 2.9 1 1 1 2 2 1 0 Seryl-tRNA synthetase N-terminal domain DUF4337 PF14235.1 EMG48109.1 - 3.1 7.6 32.5 3.9 7.2 2.5 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4337) GTPase_Cys_C PF12631.2 EMG48109.1 - 3.3 8.1 7.9 45 4.5 5.0 2.6 1 1 0 1 1 1 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Sulphotransf PF09037.5 EMG48109.1 - 3.4 7.0 10.3 0.088 12.2 1.6 2.0 1 1 0 2 2 2 0 Stf0 sulphotransferase Clr5 PF14420.1 EMG48109.1 - 3.4 7.6 9.5 1.6 8.6 0.4 3.1 3 1 0 3 3 2 0 Clr5 domain FH2 PF02181.18 EMG48109.1 - 3.5 6.4 23.8 2.8 6.7 7.5 2.5 1 1 2 3 3 3 0 Formin Homology 2 Domain Hemerythrin PF01814.18 EMG48109.1 - 3.6 7.7 12.0 1.4e+02 2.5 7.1 3.2 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain DUF479 PF04336.7 EMG48109.1 - 3.9 7.6 8.0 14 5.8 0.4 2.9 1 1 1 2 2 2 0 Protein of unknown function, DUF479 DivIVA PF05103.8 EMG48109.1 - 4.3 7.4 35.8 5.5 7.0 5.5 3.2 1 1 2 3 3 3 0 DivIVA protein Peptidase_S64 PF08192.6 EMG48109.1 - 4.5 5.4 13.9 5 5.3 9.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 Sec2p PF06428.6 EMG48109.1 - 4.8 7.0 32.4 0.97 9.3 12.3 2.9 1 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p MAD PF05557.8 EMG48109.1 - 5.1 5.0 38.1 40 2.1 26.4 2.0 1 1 0 1 1 1 0 Mitotic checkpoint protein SlyX PF04102.7 EMG48109.1 - 5.2 7.5 24.3 1.3 9.4 4.2 3.8 2 2 2 4 4 4 0 SlyX Allexi_40kDa PF05549.6 EMG48109.1 - 5.5 6.2 17.8 3.2 6.9 2.2 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein Rootletin PF15035.1 EMG48109.1 - 5.6 6.8 35.2 5.7 6.8 17.2 2.4 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Filo_VP35 PF02097.10 EMG48109.1 - 6.8 5.7 8.4 3.1 6.8 3.7 1.7 1 1 1 2 2 2 0 Filoviridae VP35 DUF2458 PF10454.4 EMG48109.1 - 6.9 6.5 24.1 2.8 7.7 3.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2458) Spc24 PF08286.6 EMG48109.1 - 7.6 6.2 39.2 1.9 8.2 2.5 4.0 1 1 2 3 3 2 0 Spc24 subunit of Ndc80 Uds1 PF15456.1 EMG48109.1 - 9.7 6.2 31.0 17 5.4 15.3 3.1 1 1 1 2 2 2 0 Up-regulated During Septation Lin-8 PF03353.10 EMG48111.1 - 2.5 7.2 33.9 1 8.5 9.6 2.5 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Ribosomal_S13 PF00416.17 EMG48112.1 - 2.3e-24 85.8 0.1 2.8e-24 85.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EMG48112.1 - 0.0035 15.9 0.0 0.0035 15.9 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF3610 PF12272.3 EMG48112.1 - 0.055 13.1 0.0 0.063 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3610) H2TH PF06831.9 EMG48112.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain zf-C2H2_2 PF12756.2 EMG48113.1 - 4.5e-33 113.3 7.0 2.4e-30 104.6 0.8 2.8 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EMG48113.1 - 0.0021 18.1 0.3 0.0021 18.1 0.2 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EMG48113.1 - 0.13 12.6 8.5 2.9 8.4 0.0 3.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-Di19 PF05605.7 EMG48113.1 - 0.27 11.3 3.0 19 5.4 0.0 2.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding AKAP95 PF04988.7 EMG48113.1 - 0.9 9.2 17.4 0.17 11.6 1.4 3.2 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zinc_ribbon_2 PF13240.1 EMG48113.1 - 1.1 8.7 4.3 14 5.2 0.0 3.4 3 0 0 3 3 3 0 zinc-ribbon domain DnaJ PF00226.26 EMG48114.1 - 2.1e-20 72.2 0.6 3.5e-20 71.4 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EMG48114.1 - 2.8e-12 46.3 6.6 5.1e-06 26.2 1.0 5.2 3 1 0 3 3 3 3 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EMG48114.1 - 3.4e-09 36.6 11.3 6.8e-09 35.6 7.9 1.5 1 0 0 1 1 1 1 DnaJ central domain Vac14_Fig4_bd PF11916.3 EMG48115.1 - 6.9e-69 230.6 13.0 1.6e-68 229.4 9.0 1.6 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EMG48115.1 - 2.2e-37 127.3 1.2 1.1e-35 121.9 0.3 3.1 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 EMG48115.1 - 5.3e-06 26.6 0.0 0.0078 16.4 0.0 5.1 6 2 1 7 7 7 1 HEAT repeats HEAT PF02985.17 EMG48115.1 - 0.00021 21.0 0.3 0.028 14.5 0.0 4.1 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 EMG48115.1 - 0.0011 19.3 0.0 0.34 11.4 0.0 3.9 3 0 0 3 3 3 1 HEAT-like repeat DUF2457 PF10446.4 EMG48115.1 - 0.39 9.3 22.6 0.63 8.7 15.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.5 EMG48115.1 - 3.6 6.5 17.1 6.1 5.7 11.8 1.3 1 0 0 1 1 1 0 BUD22 AAA_11 PF13086.1 EMG48116.1 - 0.0034 16.9 0.3 0.0099 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMG48116.1 - 0.093 12.4 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Part of AAA domain AAA_12 PF13087.1 EMG48117.1 - 1.4e-18 67.0 0.0 1.7e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EMG48117.1 - 0.019 14.5 0.0 0.04 13.4 0.0 1.4 2 0 0 2 2 2 0 AAA domain GSH_synth_ATP PF03917.12 EMG48118.1 - 3.1e-119 397.8 0.1 3.9e-119 397.5 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EMG48118.1 - 2.4e-39 133.6 0.1 4.5e-39 132.7 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase EI24 PF07264.6 EMG48119.1 - 0.063 12.7 20.1 0.41 10.0 13.9 2.0 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) FUSC-like PF12805.2 EMG48119.1 - 0.67 8.8 7.7 1.1 8.1 5.3 1.3 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Cys_Met_Meta_PP PF01053.15 EMG48121.1 - 2.8e-140 466.9 0.0 3.2e-140 466.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EMG48121.1 - 0.00011 21.2 0.1 0.00016 20.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EMG48121.1 - 0.0024 16.9 0.1 0.0052 15.8 0.1 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family MtrE PF04206.7 EMG48121.1 - 0.071 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit E WD40 PF00400.27 EMG48122.1 - 2.9e-09 36.4 3.0 5.2e-05 22.9 0.1 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF2415 PF10313.4 EMG48122.1 - 3.7e-05 23.3 0.0 0.12 12.1 0.0 3.9 4 0 0 4 4 4 2 Uncharacterised protein domain (DUF2415) TauD PF02668.11 EMG48123.1 - 1.3e-46 159.3 0.0 1.5e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RCC1 PF00415.13 EMG48124.1 - 3.6e-29 100.7 15.2 3e-07 30.5 0.1 6.5 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMG48124.1 - 8e-22 76.3 22.8 2.3e-10 39.8 0.2 6.4 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.1 EMG48124.1 - 0.029 14.4 0.3 20 5.3 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4213) DUF775 PF05603.7 EMG48125.1 - 4.2e-65 219.0 0.1 4.8e-65 218.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) DUF3407 PF11887.3 EMG48126.1 - 0.028 13.7 1.5 0.043 13.1 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3407) DUF310 PF03750.8 EMG48126.1 - 0.034 14.3 0.5 0.034 14.3 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF310) DDE_Tnp_1_3 PF13612.1 EMG48126.1 - 0.52 10.0 4.7 0.46 10.2 2.5 1.5 1 1 0 1 1 1 0 Transposase DDE domain DUF1843 PF08898.5 EMG48126.1 - 0.6 10.1 3.7 0.7 9.9 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DUF4107 PF13389.1 EMG48126.1 - 0.66 9.6 4.0 7.7 6.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4107) CaM_binding PF07839.6 EMG48126.1 - 0.73 10.0 6.8 0.15 12.2 0.6 2.3 1 1 0 2 2 2 0 Plant calmodulin-binding domain Pup PF05639.6 EMG48126.1 - 4.4 7.8 8.0 5.1 7.6 3.2 2.5 1 1 1 2 2 2 0 Pup-like protein ATG16 PF08614.6 EMG48126.1 - 6.3 6.5 19.0 0.41 10.4 6.2 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF16 PF01519.11 EMG48126.1 - 8.1 6.7 18.6 0.13 12.5 6.1 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 Lzipper-MIP1 PF14389.1 EMG48126.1 - 10 6.3 14.8 1.7 8.8 2.6 3.5 2 2 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 PP2C PF00481.16 EMG48127.1 - 5.5e-42 143.9 0.0 1.4e-41 142.6 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EMG48127.1 - 0.016 14.6 0.0 0.044 13.1 0.0 1.8 1 1 0 1 1 1 0 Protein phosphatase 2C MFS_1 PF07690.11 EMG48128.1 - 2.4e-18 65.9 25.9 3.4e-18 65.4 17.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4500 PF14937.1 EMG48128.1 - 0.035 13.9 0.1 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) DUF1399 PF07173.7 EMG48129.1 - 8.2e-33 113.5 3.4 4.2e-32 111.2 0.2 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1399) ABC_tran PF00005.22 EMG48130.1 - 2.1e-50 170.6 0.4 8.6e-31 107.0 0.0 3.4 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EMG48130.1 - 3.5e-50 170.9 45.4 5.6e-27 94.8 13.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EMG48130.1 - 1.5e-09 38.2 16.8 3.2e-05 24.0 0.0 6.0 4 2 1 5 5 4 2 AAA domain AAA_29 PF13555.1 EMG48130.1 - 1.3e-07 31.0 1.2 0.001 18.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EMG48130.1 - 3.5e-07 29.6 6.5 0.0028 16.9 0.4 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EMG48130.1 - 4.2e-05 24.3 7.0 0.016 16.0 0.1 3.8 3 1 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 EMG48130.1 - 7.1e-05 22.7 1.0 0.53 10.2 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EMG48130.1 - 0.00012 21.3 1.1 0.095 11.8 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EMG48130.1 - 0.00028 21.3 0.5 0.85 10.1 0.1 3.1 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 EMG48130.1 - 0.0028 17.6 2.3 0.077 12.9 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 EMG48130.1 - 0.0033 17.0 0.2 1.5 8.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain ATP_bind_1 PF03029.12 EMG48130.1 - 0.0042 16.6 0.6 7.6 5.9 0.0 3.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein T2SE PF00437.15 EMG48130.1 - 0.0044 15.9 0.0 0.072 11.9 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein Zeta_toxin PF06414.7 EMG48130.1 - 0.0054 15.8 0.7 1.6 7.7 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.1 EMG48130.1 - 0.0054 16.1 0.0 1.7 8.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 EMG48130.1 - 0.028 13.9 0.5 0.48 9.8 0.1 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ArgK PF03308.11 EMG48130.1 - 0.028 13.2 0.8 0.63 8.7 0.1 2.2 2 0 0 2 2 2 0 ArgK protein Dynamin_N PF00350.18 EMG48130.1 - 0.028 14.2 0.5 0.028 14.2 0.3 4.2 5 0 0 5 5 5 0 Dynamin family FtsK_SpoIIIE PF01580.13 EMG48130.1 - 0.035 13.5 0.6 7.8 5.9 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.1 EMG48130.1 - 0.11 12.6 4.8 8.2 6.5 0.2 3.4 2 1 0 2 2 2 0 AAA domain CDC45 PF02724.9 EMG48130.1 - 0.15 10.0 16.6 3.5 5.5 9.4 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF87 PF01935.12 EMG48130.1 - 1 9.1 9.8 2.1 8.1 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 YL1 PF05764.8 EMG48130.1 - 9.2 5.7 28.1 0.41 10.2 11.3 2.2 2 0 0 2 2 2 0 YL1 nuclear protein UQ_con PF00179.21 EMG48131.1 - 3.3e-43 146.4 0.1 3.7e-43 146.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMG48131.1 - 1.7e-06 27.7 0.0 2.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EMG48131.1 - 0.035 13.7 0.6 0.068 12.8 0.4 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 EMG48131.1 - 0.068 13.0 1.7 0.12 12.2 1.2 1.8 1 1 0 1 1 1 0 RWD domain His_Phos_1 PF00300.17 EMG48132.1 - 4.7e-31 108.0 0.0 6.8e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 6PF2K PF01591.13 EMG48132.1 - 3.3e-12 45.9 2.0 0.00078 18.5 0.1 3.2 2 1 1 3 3 3 3 6-phosphofructo-2-kinase INTS2 PF14750.1 EMG48132.1 - 0.13 9.7 0.0 0.18 9.2 0.0 1.1 1 0 0 1 1 1 0 Integrator complex subunit 2 cNMP_binding PF00027.24 EMG48133.1 - 3.5e-32 110.0 0.8 1.8e-16 59.6 0.0 5.2 6 0 0 6 6 6 2 Cyclic nucleotide-binding domain Patatin PF01734.17 EMG48133.1 - 1.3e-20 74.1 2.6 7e-19 68.5 1.8 2.7 1 1 0 1 1 1 1 Patatin-like phospholipase Pex19 PF04614.7 EMG48134.1 - 2.2e-82 276.4 17.7 2.2e-82 276.4 12.3 1.5 1 1 0 1 1 1 1 Pex19 protein family BCDHK_Adom3 PF10436.4 EMG48134.1 - 0.25 10.8 1.8 0.3 10.5 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF342 PF03961.8 EMG48134.1 - 0.88 7.9 9.4 0.74 8.1 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF506 PF04720.7 EMG48134.1 - 1.2 8.7 9.3 0.36 10.4 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF506) Exonuc_VII_L PF02601.10 EMG48134.1 - 1.9 7.5 11.5 19 4.2 8.0 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit FliE PF02049.13 EMG48134.1 - 3 7.9 7.7 9.9 6.2 0.3 3.3 2 1 2 4 4 4 0 Flagellar hook-basal body complex protein FliE AAA PF00004.24 EMG48135.1 - 2.6e-88 292.9 0.0 1.3e-42 145.1 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMG48135.1 - 6.4e-13 49.0 0.0 4.2e-07 30.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.7 EMG48135.1 - 7.5e-11 41.5 0.1 0.00083 18.4 0.1 3.2 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EMG48135.1 - 6.9e-10 39.1 1.5 0.00074 19.6 0.1 4.8 3 2 1 4 4 3 1 AAA domain AAA_5 PF07728.9 EMG48135.1 - 3.4e-09 36.5 0.1 0.0056 16.4 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EMG48135.1 - 6e-09 35.8 0.0 0.00024 21.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EMG48135.1 - 9.5e-09 35.3 0.0 0.0019 18.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 EMG48135.1 - 5.7e-07 28.5 0.3 0.019 13.6 0.0 2.6 3 0 0 3 3 3 2 TIP49 C-terminus RNA_helicase PF00910.17 EMG48135.1 - 3.9e-06 26.9 0.0 0.042 14.0 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.1 EMG48135.1 - 7.4e-06 25.8 0.0 0.0071 16.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EMG48135.1 - 1.1e-05 24.7 0.1 0.031 13.4 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EMG48135.1 - 1.1e-05 26.2 0.0 0.14 12.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain Bac_DnaA PF00308.13 EMG48135.1 - 1.1e-05 25.1 0.0 0.00038 20.1 0.0 2.7 2 1 0 2 2 2 1 Bacterial dnaA protein Zeta_toxin PF06414.7 EMG48135.1 - 1.8e-05 23.9 0.0 0.089 11.8 0.0 2.7 3 0 0 3 3 3 2 Zeta toxin AAA_19 PF13245.1 EMG48135.1 - 2.4e-05 24.0 2.8 0.0019 17.9 0.2 2.9 2 0 0 2 2 2 1 Part of AAA domain Rad17 PF03215.10 EMG48135.1 - 7.5e-05 21.5 0.1 0.085 11.5 0.1 2.9 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 EMG48135.1 - 0.00018 21.4 0.0 0.26 11.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EMG48135.1 - 0.00019 21.1 0.0 4.4 6.9 0.0 3.5 2 2 1 3 3 3 0 Archaeal ATPase AAA_25 PF13481.1 EMG48135.1 - 0.0002 20.8 6.0 1 8.7 0.0 4.0 2 2 1 3 3 3 2 AAA domain CDC48_N PF02359.13 EMG48135.1 - 0.00035 20.4 0.0 0.0011 18.9 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain ABC_tran PF00005.22 EMG48135.1 - 0.00035 20.8 0.0 0.017 15.4 0.0 2.7 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.7 EMG48135.1 - 0.00054 19.6 0.2 0.019 14.6 0.0 3.2 4 0 0 4 4 4 1 NACHT domain Viral_helicase1 PF01443.13 EMG48135.1 - 0.0006 19.4 0.0 0.05 13.1 0.0 3.4 5 0 0 5 5 4 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 EMG48135.1 - 0.0008 19.0 0.0 0.054 13.0 0.0 2.4 1 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EMG48135.1 - 0.00099 18.7 0.0 1.2 8.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EMG48135.1 - 0.0016 17.8 0.3 1.7 8.0 0.1 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 EMG48135.1 - 0.0024 17.9 0.0 0.25 11.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Molydop_binding PF01568.16 EMG48135.1 - 0.003 17.3 0.0 0.017 14.9 0.0 2.2 1 1 1 2 2 2 1 Molydopterin dinucleotide binding domain KaiC PF06745.8 EMG48135.1 - 0.0083 15.2 0.7 6.8 5.7 0.1 3.5 2 1 1 3 3 3 0 KaiC AAA_18 PF13238.1 EMG48135.1 - 0.0092 16.2 0.0 0.31 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EMG48135.1 - 0.015 14.2 0.0 0.34 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.1 EMG48135.1 - 0.022 14.3 0.1 0.18 11.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EMG48135.1 - 0.024 14.1 0.5 4.6 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EMG48135.1 - 0.043 13.2 0.0 12 5.3 0.0 3.3 3 1 0 3 3 3 0 Sigma-54 interaction domain UPF0079 PF02367.12 EMG48135.1 - 0.048 13.2 0.1 0.91 9.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AFG1_ATPase PF03969.11 EMG48135.1 - 0.16 10.7 0.0 0.5 9.1 0.0 1.8 2 0 0 2 2 2 0 AFG1-like ATPase DSHCT PF08148.7 EMG48136.1 - 3.3e-60 202.3 0.6 7.3e-60 201.2 0.4 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EMG48136.1 - 1e-22 80.4 0.0 2.9e-22 78.9 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG48136.1 - 5.2e-06 26.2 0.0 1.6e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 EMG48136.1 - 0.0023 17.1 1.3 0.083 12.0 0.9 2.4 1 1 0 1 1 1 1 rRNA-processing arch domain Ras PF00071.17 EMG48137.1 - 3.3e-58 195.6 0.0 4e-58 195.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMG48137.1 - 4.6e-19 69.0 0.0 7e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMG48137.1 - 1.5e-15 56.8 0.0 1.6e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMG48137.1 - 3.8e-08 32.7 0.0 4.8e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMG48137.1 - 2.6e-06 26.9 0.0 7.7e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMG48137.1 - 4e-05 23.5 0.0 6.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EMG48137.1 - 0.0044 17.0 0.0 0.0057 16.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EMG48137.1 - 0.064 12.4 0.0 0.37 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EMG48137.1 - 0.098 12.8 0.0 0.21 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain N2227 PF07942.7 EMG48138.1 - 1.5e-65 220.9 0.0 2.5e-65 220.1 0.0 1.4 1 0 0 1 1 1 1 N2227-like protein Methyltransf_31 PF13847.1 EMG48138.1 - 7.8e-06 25.5 0.1 0.0013 18.2 0.1 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EMG48138.1 - 2e-05 24.9 0.0 0.0027 18.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMG48138.1 - 0.00012 22.5 0.0 0.0021 18.4 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMG48138.1 - 0.028 14.1 0.0 0.072 12.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Hid1 PF12722.2 EMG48138.1 - 0.087 10.4 0.1 0.12 10.0 0.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NNMT_PNMT_TEMT PF01234.12 EMG48138.1 - 0.11 11.4 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family NMT1 PF09084.6 EMG48139.1 - 2.1e-13 50.3 0.0 3.8e-13 49.5 0.0 1.4 1 1 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EMG48139.1 - 2.8e-05 23.6 0.0 4.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 NMT1-like family DUF3834 PF12916.2 EMG48139.1 - 0.016 14.1 0.1 0.046 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) ApoLp-III PF07464.6 EMG48139.1 - 0.025 14.5 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) TPR_11 PF13414.1 EMG48140.1 - 1.2e-07 31.2 0.1 9.7e-07 28.3 0.0 2.2 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 EMG48140.1 - 0.0004 20.2 1.4 0.001 18.9 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMG48140.1 - 0.0048 16.4 0.0 0.72 9.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMG48140.1 - 0.011 15.6 0.0 2.1 8.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DASH_Dad4 PF08650.5 EMG48141.1 - 1.3e-15 57.0 2.3 1.4e-15 56.9 1.6 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 Lge1 PF11488.3 EMG48141.1 - 0.12 12.5 0.1 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 DUF1744 PF08490.7 EMG48142.1 - 3.5e-158 526.3 1.7 5e-158 525.8 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EMG48142.1 - 5.8e-63 212.7 5.8 1.1e-62 211.7 3.1 2.1 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EMG48142.1 - 4.1e-22 78.6 0.1 1.1e-21 77.1 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EMG48142.1 - 9.9e-07 28.4 0.1 4.2e-06 26.4 0.1 2.0 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EMG48142.1 - 2.4e-05 24.2 0.3 0.00013 21.7 0.0 2.5 2 0 0 2 2 2 1 RNase_H superfamily zf-DNA_Pol PF08996.5 EMG48142.1 - 0.0077 15.6 10.4 0.018 14.4 7.2 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger GCR1_C PF12550.3 EMG48143.1 - 1.3e-10 41.0 1.3 1.2e-09 37.8 0.9 2.7 1 1 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Phage_int_SAM_1 PF02899.12 EMG48143.1 - 1.5e-07 31.5 4.4 0.00017 21.6 0.2 3.1 3 0 0 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.1 EMG48143.1 - 0.0025 18.0 13.7 0.045 14.0 0.7 4.2 3 1 1 4 4 4 2 Phage integrase, N-terminal SAM-like domain SATase_N PF06426.9 EMG48143.1 - 0.0045 17.2 1.7 2.5 8.4 0.1 3.4 3 0 0 3 3 3 2 Serine acetyltransferase, N-terminal DUF1864 PF08933.6 EMG48143.1 - 0.0081 14.7 0.1 0.036 12.5 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1864) DUF3440 PF11922.3 EMG48143.1 - 0.2 11.1 9.5 0.77 9.2 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3440) Alg6_Alg8 PF03155.10 EMG48144.1 - 2.8e-89 300.1 10.8 3.6e-89 299.7 7.5 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family KH_1 PF00013.24 EMG48145.1 - 2.3e-07 30.3 0.3 1e-06 28.2 0.0 2.2 2 1 0 2 2 2 1 KH domain KH_3 PF13014.1 EMG48145.1 - 2.2e-05 23.9 0.6 6.1e-05 22.5 0.1 2.1 2 0 0 2 2 2 1 KH domain KH_4 PF13083.1 EMG48145.1 - 0.00068 19.2 0.3 0.0032 17.0 0.0 2.3 3 0 0 3 3 3 1 KH domain DBD_Tnp_Mut PF03108.10 EMG48145.1 - 0.13 11.8 0.2 0.45 10.1 0.1 1.9 2 0 0 2 2 2 0 MuDR family transposase HSP70 PF00012.15 EMG48146.1 - 1.2e-235 783.1 10.2 1.3e-235 782.9 7.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMG48146.1 - 3e-17 62.2 0.7 1.4e-15 56.7 0.2 2.2 2 0 0 2 2 2 2 MreB/Mbl protein ATP-synt_DE PF00401.15 EMG48146.1 - 0.026 14.4 1.6 0.026 14.4 1.1 2.6 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain RIO1 PF01163.17 EMG48147.1 - 1.2e-43 148.7 0.8 2.1e-43 147.8 0.6 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 EMG48147.1 - 1.3e-32 111.6 0.2 7.8e-32 109.2 0.0 2.1 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.18 EMG48147.1 - 7e-08 32.5 0.0 0.0027 17.4 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EMG48147.1 - 1.5e-05 24.1 0.1 0.00074 18.6 0.0 2.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NOA36 PF06524.7 EMG48147.1 - 0.014 14.6 17.1 0.023 13.9 11.9 1.2 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.3 EMG48147.1 - 0.18 11.6 22.7 0.3 11.0 15.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.7 EMG48147.1 - 0.27 9.1 26.4 0.36 8.6 18.3 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EMG48147.1 - 2.5 6.4 22.9 3.5 5.9 15.9 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EMG48147.1 - 7.4 4.4 18.7 11 3.9 13.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DCP2 PF05026.8 EMG48149.1 - 2.3e-35 120.3 2.5 2.7e-34 116.9 0.1 2.5 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.23 EMG48149.1 - 4.5e-18 65.1 0.0 1.7e-17 63.2 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain ATP-synt_10 PF05176.9 EMG48150.1 - 2.1e-87 292.5 0.0 2.6e-87 292.2 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Ribosomal_S10 PF00338.17 EMG48151.1 - 3.9e-29 100.3 1.0 5.1e-29 99.9 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e RasGEF PF00617.14 EMG48152.1 - 1.2e-49 168.6 3.6 3e-49 167.3 2.5 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EMG48152.1 - 1.6e-14 53.8 0.3 1.6e-14 53.8 0.2 2.8 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.23 EMG48152.1 - 0.0006 19.1 0.0 0.0015 17.8 0.0 1.8 1 0 0 1 1 1 1 SH3 domain FAD_binding_8 PF08022.7 EMG48153.1 - 1.8e-22 79.1 0.0 3.3e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EMG48153.1 - 1e-20 74.2 0.1 2e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMG48153.1 - 7.4e-20 71.3 17.7 7.4e-20 71.3 12.3 2.6 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EMG48153.1 - 0.01 16.3 0.0 0.062 13.8 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.7 EMG48154.1 - 6.6e-22 77.3 0.0 1.7e-21 76.0 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EMG48154.1 - 1.1e-21 77.3 0.1 2.8e-21 76.0 0.1 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMG48154.1 - 4.8e-14 52.5 14.5 8.7e-14 51.6 9.1 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component DEAD PF00270.24 EMG48154.1 - 2e-09 37.1 0.2 4.5e-09 36.0 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EMG48154.1 - 0.0031 16.4 0.1 0.0058 15.5 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF1804 PF08822.6 EMG48154.1 - 0.075 12.7 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) NAD_binding_1 PF00175.16 EMG48154.1 - 0.12 12.9 0.0 0.43 11.1 0.0 2.0 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain LIP PF03583.9 EMG48155.1 - 5.3e-120 400.0 0.6 6.3e-120 399.7 0.4 1.0 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 EMG48155.1 - 6.8e-08 32.3 0.0 1.2e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMG48155.1 - 0.021 14.7 0.0 0.095 12.5 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMG48155.1 - 0.038 13.1 3.1 3.8 6.6 0.0 2.9 3 1 0 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EMG48155.1 - 0.047 13.1 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PIF1 PF05970.9 EMG48156.1 - 9.3e-62 209.0 3.1 3.4e-47 161.1 0.4 2.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EMG48156.1 - 5.7e-15 55.4 0.0 1.1e-13 51.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EMG48156.1 - 5.1e-06 26.6 0.0 1.5e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 EMG48156.1 - 1e-05 23.5 1.6 0.00019 19.3 0.0 2.3 2 1 0 2 2 2 1 Helicase UvrD_C_2 PF13538.1 EMG48156.1 - 1.1e-05 25.5 0.0 0.0015 18.6 0.0 2.7 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EMG48156.1 - 0.00025 20.7 1.5 0.00067 19.3 1.0 1.8 1 1 0 1 1 1 1 Part of AAA domain AAA PF00004.24 EMG48156.1 - 0.00049 20.3 0.0 0.0015 18.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EMG48156.1 - 0.0029 16.6 0.5 0.067 12.1 0.1 2.6 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 EMG48156.1 - 0.012 15.1 0.4 2.3 7.6 0.2 2.9 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EMG48156.1 - 0.016 15.1 0.2 0.054 13.4 0.1 1.9 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EMG48156.1 - 0.026 14.0 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.7 EMG48156.1 - 0.04 13.5 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 NACHT domain T2SE PF00437.15 EMG48156.1 - 0.049 12.5 0.1 0.11 11.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 EMG48156.1 - 0.06 12.7 3.8 4.5 6.6 0.3 2.9 3 0 0 3 3 3 0 AAA-like domain AAA_5 PF07728.9 EMG48156.1 - 0.11 12.1 1.0 1.5 8.5 0.3 3.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Helicase_RecD PF05127.9 EMG48156.1 - 0.15 11.6 0.7 0.99 9.0 0.5 2.3 1 1 0 1 1 1 0 Helicase Sec39 PF08314.6 EMG48157.1 - 5.9e-62 209.6 31.2 7.7e-62 209.2 21.6 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 LSM PF01423.17 EMG48158.1 - 3.5e-17 61.7 0.0 3.9e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF2272 PF10030.4 EMG48158.1 - 0.057 12.8 0.0 0.063 12.7 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2272) Mnd1 PF03962.10 EMG48159.1 - 1.2e-28 100.0 6.7 1.6e-28 99.6 4.6 1.2 1 0 0 1 1 1 1 Mnd1 family TMF_TATA_bd PF12325.3 EMG48159.1 - 0.022 14.4 5.0 0.039 13.6 3.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding GAS PF13851.1 EMG48159.1 - 0.024 13.8 7.3 0.14 11.3 5.3 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 EMG48159.1 - 0.025 14.0 2.6 0.55 9.7 0.1 2.3 2 0 0 2 2 2 0 Septum formation initiator HALZ PF02183.13 EMG48159.1 - 0.045 13.4 0.5 2.5 7.9 0.0 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper POX PF07526.6 EMG48159.1 - 0.053 13.7 4.1 0.13 12.4 2.9 1.7 1 1 0 1 1 1 0 Associated with HOX DUF1043 PF06295.7 EMG48159.1 - 0.053 13.1 5.3 0.23 11.1 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) YlqD PF11068.3 EMG48159.1 - 0.063 13.3 5.3 0.081 12.9 3.7 1.1 1 0 0 1 1 1 0 YlqD protein YueH PF14166.1 EMG48159.1 - 0.068 12.9 1.3 0.33 10.7 0.0 2.3 2 0 0 2 2 2 0 YueH-like protein DUF342 PF03961.8 EMG48159.1 - 0.075 11.4 1.9 0.085 11.2 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CENP-Q PF13094.1 EMG48159.1 - 0.099 12.6 3.4 0.13 12.2 2.4 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CENP-H PF05837.7 EMG48159.1 - 0.19 11.8 3.6 0.27 11.4 2.5 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF3598 PF12204.3 EMG48159.1 - 0.23 10.6 3.2 0.38 9.9 2.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3598) TBPIP PF07106.8 EMG48159.1 - 0.51 9.8 7.0 0.69 9.4 4.9 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Cep57_MT_bd PF06657.8 EMG48159.1 - 2.9 7.9 7.4 3.6 7.6 1.6 2.3 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Sugar_tr PF00083.19 EMG48160.1 - 1.5e-45 155.6 15.6 1.6e-45 155.5 10.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG48160.1 - 6.1e-08 31.7 11.4 8.2e-08 31.3 7.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG48161.1 - 1.6e-45 155.5 11.0 1.9e-45 155.3 7.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG48161.1 - 2.4e-15 56.1 13.3 3e-15 55.8 9.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OMP_b-brl_2 PF13568.1 EMG48161.1 - 0.083 12.6 1.4 2.8 7.7 0.1 2.6 3 0 0 3 3 3 0 Outer membrane protein beta-barrel domain GMC_oxred_N PF00732.14 EMG48162.1 - 7.5e-22 77.8 0.2 9.5e-22 77.5 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EMG48162.1 - 3.5e-05 22.8 0.1 5.1e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMG48162.1 - 0.00017 21.5 0.1 0.00034 20.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMG48162.1 - 0.012 15.4 0.2 0.018 14.9 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Stirrup PF09061.1 EMG48162.1 - 0.041 13.7 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Stirrup DAO PF01266.19 EMG48162.1 - 0.065 12.1 0.0 0.093 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EMG48162.1 - 0.1 11.6 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain GMC_oxred_C PF05199.8 EMG48163.1 - 4.3e-26 91.9 0.2 6.6e-26 91.3 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase AAA_2 PF07724.9 EMG48164.1 - 7.8e-46 156.0 0.1 2.9e-45 154.2 0.0 2.0 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EMG48164.1 - 6.9e-22 77.1 0.2 1.9e-21 75.7 0.1 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EMG48164.1 - 2.4e-10 40.2 0.2 4.8e-09 36.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EMG48164.1 - 2.3e-07 31.0 0.0 6.4e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EMG48164.1 - 4.7e-07 29.4 0.0 2.2e-06 27.2 0.0 2.1 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.1 EMG48164.1 - 3e-05 24.0 5.6 9.2e-05 22.5 0.0 3.3 3 1 1 4 4 4 1 AAA ATPase domain Mg_chelatase PF01078.16 EMG48164.1 - 0.00028 20.1 0.0 0.41 9.7 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 EMG48164.1 - 0.00067 19.7 0.0 0.0032 17.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMG48164.1 - 0.00069 19.5 0.0 0.002 18.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 EMG48164.1 - 0.006 17.3 1.1 0.029 15.2 0.7 2.5 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EMG48164.1 - 0.011 15.3 0.0 0.045 13.3 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.6 EMG48164.1 - 0.019 14.8 0.0 0.057 13.3 0.0 1.7 2 0 0 2 2 1 0 Torsin Zeta_toxin PF06414.7 EMG48164.1 - 0.024 13.7 0.0 0.071 12.1 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 EMG48164.1 - 0.026 14.4 0.0 0.072 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EMG48164.1 - 0.038 13.4 0.0 0.16 11.3 0.0 2.1 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain APS_kinase PF01583.15 EMG48164.1 - 0.081 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_10 PF12846.2 EMG48164.1 - 0.1 11.9 0.1 0.16 11.3 0.1 1.7 1 1 0 1 1 1 0 AAA-like domain PEPCK_ATP PF01293.15 EMG48164.1 - 0.12 10.8 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 EMG48164.1 - 0.16 12.2 2.7 0.51 10.6 0.9 2.6 1 1 0 1 1 1 0 AAA domain SlyX PF04102.7 EMG48164.1 - 5.6 7.4 6.0 15 6.0 0.3 3.3 3 0 0 3 3 3 0 SlyX ArfGap PF01412.13 EMG48165.1 - 3.9e-32 110.4 0.8 1.1e-31 109.0 0.0 2.1 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf Clp_N PF02861.15 EMG48166.1 - 3.3e-15 55.7 1.5 2.5e-10 40.1 0.2 3.4 3 0 0 3 3 3 2 Clp amino terminal domain AAA PF00004.24 EMG48166.1 - 1.5e-13 51.1 0.0 4.3e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMG48166.1 - 2.3e-10 40.7 0.0 2e-06 27.9 0.1 2.5 1 1 1 2 2 2 2 AAA ATPase domain Arch_ATPase PF01637.13 EMG48166.1 - 5.5e-06 26.2 3.4 0.0041 16.8 0.1 2.7 2 1 1 3 3 3 2 Archaeal ATPase AAA_22 PF13401.1 EMG48166.1 - 0.0004 20.5 0.1 0.0026 17.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMG48166.1 - 0.0022 17.7 0.0 0.0068 16.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 EMG48166.1 - 0.0089 15.7 0.0 0.032 13.8 0.0 1.9 1 1 1 2 2 2 1 NACHT domain DUF258 PF03193.11 EMG48166.1 - 0.018 14.2 0.1 0.03 13.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 DUF815 PF05673.8 EMG48166.1 - 0.031 13.2 0.3 0.17 10.7 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF815) Miro PF08477.8 EMG48166.1 - 0.033 14.6 0.0 0.1 13.0 0.0 1.9 2 0 0 2 2 1 0 Miro-like protein AAA_17 PF13207.1 EMG48166.1 - 0.057 14.2 0.2 0.31 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EMG48166.1 - 0.067 12.6 0.0 0.17 11.3 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 EMG48166.1 - 0.068 13.4 0.5 1 9.7 0.0 2.7 2 1 1 3 3 3 0 AAA domain AAA_30 PF13604.1 EMG48166.1 - 0.073 12.6 0.0 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EMG48166.1 - 0.15 11.6 0.0 0.38 10.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain CDP-OH_P_transf PF01066.16 EMG48167.1 - 2.6e-20 72.6 2.8 2.6e-20 72.6 1.9 1.9 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase MtN3_slv PF03083.11 EMG48167.1 - 7 6.5 10.8 0.89 9.4 0.1 3.4 3 1 1 4 4 4 0 Sugar efflux transporter for intercellular exchange CFEM PF05730.6 EMG48168.1 - 1.1 9.1 6.5 1.8 8.4 4.5 1.4 1 0 0 1 1 1 0 CFEM domain ParA PF10609.4 EMG48169.1 - 3e-36 123.1 0.1 1.2e-35 121.2 0.1 1.9 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 EMG48169.1 - 1.4e-13 50.7 0.0 2e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 EMG48169.1 - 0.00013 21.1 0.6 0.0025 16.9 0.1 2.4 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 EMG48169.1 - 0.00023 21.1 0.0 0.0023 17.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EMG48169.1 - 0.00041 19.5 0.0 0.00083 18.5 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ DUF258 PF03193.11 EMG48169.1 - 0.0043 16.2 0.0 0.008 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EMG48169.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_26 PF13500.1 EMG48169.1 - 0.051 13.1 0.0 0.46 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EMG48169.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Nup96 PF12110.3 EMG48170.1 - 1e-46 159.3 0.1 3.2e-46 157.7 0.1 1.9 1 1 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EMG48170.1 - 5.9e-42 142.8 0.1 5.9e-42 142.8 0.1 2.4 3 0 0 3 3 3 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EMG48170.1 - 9.3e-12 45.1 150.3 9.2e-09 35.5 30.5 4.0 1 1 3 4 4 4 4 Nucleoporin FG repeat region YjeF_N PF03853.10 EMG48171.1 - 4.8e-30 104.3 0.0 7.1e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EMG48171.1 - 4.6e-10 39.9 2.4 4.6e-10 39.9 1.7 2.2 2 0 0 2 2 2 1 FDF domain mIF3 PF14877.1 EMG48172.1 - 0.12 11.7 0.1 0.15 11.4 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial translation initiation factor Frag1 PF10277.4 EMG48174.1 - 4.5e-62 209.3 21.0 5.5e-62 209.0 14.6 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Cation_ATPase_C PF00689.16 EMG48174.1 - 1.5 8.2 19.3 0.074 12.5 7.6 2.1 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus DUF2189 PF09955.4 EMG48174.1 - 5.4 6.9 12.5 0.52 10.2 3.8 2.4 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) CoA_binding_3 PF13727.1 EMG48174.1 - 7.9 6.2 11.7 7.9 6.2 0.1 3.0 3 0 0 3 3 3 0 CoA-binding domain U-box PF04564.10 EMG48175.1 - 2.1e-25 88.4 0.3 5e-25 87.2 0.0 1.8 2 0 0 2 2 2 1 U-box domain PhaP_Bmeg PF09602.5 EMG48175.1 - 0.076 12.8 0.9 2 8.2 0.2 2.1 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) V_ATPase_I PF01496.14 EMG48176.1 - 7.6e-280 930.0 4.5 8.6e-280 929.9 3.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Adeno_GP19K PF04881.8 EMG48176.1 - 0.072 12.8 1.0 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 Adenovirus GP19K RIX1 PF08167.7 EMG48177.1 - 1e-53 181.4 2.2 2e-53 180.4 1.0 2.0 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Apc5 PF12862.2 EMG48178.1 - 7.4e-32 109.0 5.5 7.4e-32 109.0 3.8 3.4 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 5 TPR_7 PF13176.1 EMG48178.1 - 0.053 13.3 0.1 8 6.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat N6-adenineMlase PF10237.4 EMG48179.1 - 3.1e-62 208.9 0.2 4.9e-62 208.3 0.1 1.3 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase IncA PF04156.9 EMG48179.1 - 0.22 11.1 4.1 0.45 10.0 2.8 1.5 1 0 0 1 1 1 0 IncA protein Transaldolase PF00923.14 EMG48179.1 - 0.67 9.0 3.5 2.1 7.3 1.7 2.1 2 0 0 2 2 2 0 Transaldolase PAT1 PF09770.4 EMG48180.1 - 7.3e-227 755.4 69.0 4.9e-226 752.7 47.8 1.8 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Chorismate_bind PF00425.13 EMG48181.1 - 5.1e-72 242.2 0.0 4.9e-71 239.0 0.0 2.1 2 0 0 2 2 2 1 chorismate binding enzyme GATase PF00117.23 EMG48181.1 - 1.4e-31 109.4 0.0 2.3e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EMG48181.1 - 1.1e-14 54.5 0.1 4.3e-14 52.6 0.0 2.0 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EMG48181.1 - 6.1e-07 29.1 0.0 1.2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 Uso1_p115_head PF04869.9 EMG48182.1 - 1.7e-128 427.8 0.3 6e-128 425.9 0.2 2.1 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Myosin_tail_1 PF01576.14 EMG48182.1 - 9e-18 63.4 349.6 3.1e-08 31.8 74.1 6.1 1 1 3 4 4 4 4 Myosin tail Filament PF00038.16 EMG48182.1 - 5e-13 49.1 283.8 3.8e-06 26.6 23.0 9.7 2 1 9 11 11 11 8 Intermediate filament protein Reo_sigmaC PF04582.7 EMG48182.1 - 2.8e-11 43.2 179.5 0.0013 17.9 8.4 13.5 1 1 13 14 14 14 10 Reovirus sigma C capsid protein AAA_13 PF13166.1 EMG48182.1 - 1.6e-09 36.8 316.8 0.013 14.0 27.3 8.5 1 1 7 8 8 8 7 AAA domain IncA PF04156.9 EMG48182.1 - 1.2e-07 31.5 339.6 0.0063 16.1 13.0 15.9 2 1 14 16 16 15 7 IncA protein HEAT_2 PF13646.1 EMG48182.1 - 1e-05 25.6 1.4 0.0011 19.2 0.0 4.0 4 0 0 4 4 3 1 HEAT repeats Tropomyosin_1 PF12718.2 EMG48182.1 - 1.2e-05 25.1 32.8 1.2e-05 25.1 22.8 16.6 3 1 14 17 17 16 5 Tropomyosin like WEMBL PF05701.6 EMG48182.1 - 3.5e-05 22.4 344.6 0.06 11.7 37.7 7.9 1 1 6 7 7 7 5 Weak chloroplast movement under blue light Syntaxin_2 PF14523.1 EMG48182.1 - 7.9e-05 22.6 12.5 7.9e-05 22.6 8.7 16.9 2 2 12 15 15 10 2 Syntaxin-like protein DUF3584 PF12128.3 EMG48182.1 - 0.00043 17.7 290.9 0.0018 15.7 44.2 8.1 2 1 7 9 9 9 7 Protein of unknown function (DUF3584) MscS_porin PF12795.2 EMG48182.1 - 0.00065 19.0 41.2 0.00065 19.0 28.6 10.9 2 1 8 10 10 8 2 Mechanosensitive ion channel porin domain ERM PF00769.14 EMG48182.1 - 0.0015 18.1 22.7 0.0015 18.1 15.8 12.5 2 1 9 12 12 10 4 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.7 EMG48182.1 - 0.0049 16.5 9.9 0.0049 16.5 6.9 17.1 2 1 16 18 18 16 5 TPR/MLP1/MLP2-like protein LPP PF04728.8 EMG48182.1 - 0.005 16.6 4.4 0.005 16.6 3.1 10.6 14 0 0 14 14 13 1 Lipoprotein leucine-zipper Baculo_PEP_C PF04513.7 EMG48182.1 - 0.14 12.0 177.6 0.039 13.7 1.9 17.1 3 1 13 19 19 18 0 Baculovirus polyhedron envelope protein, PEP, C terminus IL11 PF07400.6 EMG48182.1 - 0.38 10.2 0.0 9.6 5.6 0.0 3.2 3 0 0 3 3 3 0 Interleukin 11 AAA_27 PF13514.1 EMG48182.1 - 0.58 7.7 229.4 0.0059 14.3 35.5 5.7 1 1 3 4 4 4 0 AAA domain IKI3 PF04762.7 EMG48183.1 - 0 1169.5 3.3 0 1169.2 2.3 1.1 1 0 0 1 1 1 1 IKI3 family Clathrin PF00637.15 EMG48183.1 - 0.0007 19.2 0.6 0.0034 16.9 0.4 2.2 1 0 0 1 1 1 1 Region in Clathrin and VPS EF1_GNE PF00736.14 EMG48184.1 - 2.9e-31 107.0 1.7 2.9e-31 107.0 1.2 1.6 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EMG48184.1 - 5.3e-13 48.8 5.2 5.3e-13 48.8 3.6 2.8 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region DUF3752 PF12572.3 EMG48184.1 - 0.033 14.3 1.4 0.047 13.8 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) Fungal_trans_2 PF11951.3 EMG48185.1 - 2.1e-23 82.5 0.7 4.3e-23 81.5 0.5 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.20 EMG48186.1 - 8.3e-55 185.7 0.1 3.5e-38 131.2 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMG48186.1 - 8e-24 84.1 0.0 2.6e-23 82.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG48186.1 - 5.6e-05 22.2 0.0 0.00029 19.9 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.20 EMG48187.1 - 1.6e-63 214.2 0.1 6.7e-63 212.2 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG48187.1 - 1.7e-42 145.3 0.0 2.8e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.3 EMG48187.1 - 2e-34 118.8 4.2 8.9e-33 113.4 2.9 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Kinase-like PF14531.1 EMG48187.1 - 0.0024 16.8 0.0 0.016 14.1 0.0 2.1 1 1 0 1 1 1 1 Kinase-like Med12 PF09497.5 EMG48188.1 - 2e-23 82.1 0.1 4.9e-23 80.8 0.1 1.7 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Myosin_head PF00063.16 EMG48189.1 - 1.4e-218 727.3 8.4 2.3e-218 726.6 5.8 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EMG48189.1 - 6.9e-41 139.7 0.0 1.8e-40 138.3 0.0 1.8 1 0 0 1 1 1 1 Myosin tail AAA_22 PF13401.1 EMG48189.1 - 0.0053 16.8 0.4 0.02 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EMG48189.1 - 0.0084 16.9 0.1 0.06 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Hpr_kinase_C PF07475.7 EMG48189.1 - 0.009 15.3 0.1 2.3 7.4 0.0 2.5 2 0 0 2 2 2 2 HPr Serine kinase C-terminal domain Zeta_toxin PF06414.7 EMG48189.1 - 0.01 14.9 0.0 0.029 13.4 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin SH3_1 PF00018.23 EMG48189.1 - 0.021 14.2 0.1 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 SH3 domain SH3_9 PF14604.1 EMG48189.1 - 0.067 12.7 0.1 0.19 11.3 0.1 1.8 2 0 0 2 2 2 0 Variant SH3 domain AAA_16 PF13191.1 EMG48189.1 - 0.1 12.5 0.0 0.39 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain IQ PF00612.22 EMG48189.1 - 0.98 9.2 10.2 2.9 7.7 3.1 2.6 1 1 1 2 2 2 0 IQ calmodulin-binding motif zf-H2C2_2 PF13465.1 EMG48190.1 - 6.2e-19 67.2 46.4 1.2e-08 34.8 0.3 9.1 9 0 0 9 9 9 4 Zinc-finger double domain zf-C2H2 PF00096.21 EMG48190.1 - 7.3e-17 60.6 48.7 5.1e-05 23.3 0.3 8.7 8 0 0 8 8 8 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMG48190.1 - 3.5e-09 36.3 50.0 0.024 14.9 0.1 9.1 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMG48190.1 - 0.0016 18.2 18.7 0.17 11.8 0.2 5.6 4 1 1 5 5 5 3 C2H2-type zinc finger zf-met PF12874.2 EMG48190.1 - 0.037 14.2 1.1 0.037 14.2 0.7 7.5 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMG48190.1 - 0.045 13.9 0.8 0.045 13.9 0.5 6.3 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding AARP2CN PF08142.7 EMG48190.1 - 0.083 12.4 1.0 0.22 11.0 0.7 1.7 1 0 0 1 1 1 0 AARP2CN (NUC121) domain EMP70 PF02990.11 EMG48190.1 - 0.22 9.9 4.7 0.42 9.0 3.3 1.4 1 0 0 1 1 1 0 Endomembrane protein 70 YajC PF02699.10 EMG48190.1 - 0.35 10.5 0.8 0.85 9.3 0.6 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit SprA-related PF12118.3 EMG48191.1 - 0.093 12.0 7.9 0.19 11.0 5.5 1.5 1 0 0 1 1 1 0 SprA-related family Glyco_hydro_72 PF03198.9 EMG48192.1 - 1.1e-147 491.1 10.4 1.8e-147 490.3 7.2 1.3 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EMG48192.1 - 8.7e-26 90.2 5.3 2.3e-25 88.8 3.6 1.8 1 0 0 1 1 1 1 X8 domain B-block_TFIIIC PF04182.7 EMG48193.1 - 6.3e-20 70.8 0.1 3.9e-18 65.0 0.0 3.4 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC G-patch PF01585.18 EMG48193.1 - 7.1e-12 44.9 0.5 2.2e-11 43.3 0.1 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EMG48193.1 - 4.4e-05 23.2 0.2 4.4e-05 23.2 0.1 5.0 3 1 0 3 3 3 1 DExH-box splicing factor binding site HTH_20 PF12840.2 EMG48193.1 - 0.033 13.9 0.3 16 5.3 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain MarR_2 PF12802.2 EMG48193.1 - 0.043 13.4 0.0 0.19 11.4 0.0 2.1 1 0 0 1 1 1 0 MarR family HTH_27 PF13463.1 EMG48193.1 - 0.046 14.0 0.1 1.4 9.3 0.0 3.1 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf-MIZ PF02891.15 EMG48194.1 - 1.6e-07 30.7 0.2 3.3e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 MIZ/SP-RING zinc finger PHD_3 PF13922.1 EMG48194.1 - 1.8 8.8 4.9 11 6.2 3.4 2.4 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx DUF3294 PF07957.6 EMG48195.1 - 1.4e-62 211.1 8.5 1.7e-62 210.7 5.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) DUF3826 PF12875.2 EMG48195.1 - 0.024 14.3 3.5 0.89 9.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3826) DUF1664 PF07889.7 EMG48195.1 - 0.17 11.6 6.2 0.16 11.7 2.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) RNA_pol_Rpb4 PF03874.11 EMG48195.1 - 0.39 10.7 0.2 0.39 10.7 0.1 2.6 3 1 0 3 3 3 0 RNA polymerase Rpb4 SlyX PF04102.7 EMG48195.1 - 1.1 9.6 5.1 5.6 7.4 1.4 2.5 2 0 0 2 2 2 0 SlyX Sec66 PF09802.4 EMG48196.1 - 3.9e-69 231.8 2.5 4.3e-69 231.7 1.7 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Rep_fac_C PF08542.6 EMG48196.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Replication factor C C-terminal domain MIP PF00230.15 EMG48197.1 - 1.2e-44 152.4 16.2 1.5e-44 152.1 11.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein RabGAP-TBC PF00566.13 EMG48199.1 - 7.5e-44 149.7 11.6 6e-43 146.8 8.1 2.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain HSP70 PF00012.15 EMG48200.1 - 2.1e-80 270.3 3.0 8.9e-80 268.2 1.0 1.9 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EMG48200.1 - 2.6e-08 32.8 0.0 4.1e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Actin PF00022.14 EMG48200.1 - 0.0083 14.5 0.0 0.014 13.8 0.0 1.4 1 0 0 1 1 1 1 Actin Myb_DNA-binding PF00249.26 EMG48202.1 - 4.7e-33 112.9 6.5 4e-13 49.1 0.1 3.9 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMG48202.1 - 6.8e-31 106.1 2.8 3.9e-12 46.0 0.0 4.2 2 2 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EMG48202.1 - 0.0055 16.8 7.5 0.067 13.3 0.1 4.2 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 EMG48202.1 - 0.028 14.3 1.5 4.5 7.2 0.8 3.2 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 EMG48202.1 - 0.028 14.2 0.0 0.39 10.5 0.0 2.8 2 0 0 2 2 2 0 Rap1 Myb domain CENP-B_dimeris PF09026.5 EMG48202.1 - 0.094 12.9 11.6 0.48 10.6 8.0 2.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 EMG48202.1 - 0.82 8.8 7.6 2.6 7.2 5.3 1.8 1 0 0 1 1 1 0 NOA36 protein Myb_DNA-bind_5 PF13873.1 EMG48202.1 - 2.7 7.9 9.7 5.7 6.9 0.0 4.5 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain THF_DHG_CYH PF00763.18 EMG48203.1 - 1.7e-21 76.4 0.0 3.1e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EMG48203.1 - 1.5e-15 56.6 0.0 5.6e-12 45.0 0.0 3.1 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.19 EMG48203.1 - 0.0016 18.7 0.0 0.0027 18.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EMG48203.1 - 0.033 14.3 0.0 1.6 8.8 0.0 2.2 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF4097 PF13349.1 EMG48204.1 - 0.057 12.9 4.4 0.28 10.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4097) SID-1_RNA_chan PF13965.1 EMG48204.1 - 0.082 11.0 0.7 0.085 11.0 0.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Uds1 PF15456.1 EMG48204.1 - 0.41 10.6 3.2 0.58 10.1 2.2 1.3 1 0 0 1 1 1 0 Up-regulated During Septation DUF1157 PF06636.6 EMG48204.1 - 2.2 6.7 5.4 6.5 5.2 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1157) DUF4179 PF13786.1 EMG48204.1 - 5.1 7.3 5.8 29 4.9 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4179) p450 PF00067.17 EMG48205.1 - 6.1e-48 163.4 0.0 7.6e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Vac7 PF12751.2 EMG48206.1 - 5.3e-17 61.7 23.9 3.1e-12 46.0 1.1 4.0 2 1 0 3 3 3 2 Vacuolar segregation subunit 7 Gly-zipper_OmpA PF13436.1 EMG48207.1 - 0.00087 18.9 4.8 0.00087 18.9 3.3 2.3 1 1 1 2 2 2 1 Glycine-zipper containing OmpA-like membrane domain KIAA1328 PF15369.1 EMG48207.1 - 0.16 11.7 1.5 0.21 11.3 1.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Exo_endo_phos PF03372.18 EMG48209.1 - 0.0025 17.7 0.0 0.0029 17.6 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Kin17_mid PF10357.4 EMG48210.1 - 3.4e-36 123.6 0.7 3.4e-36 123.6 0.5 1.7 1 1 1 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 EMG48210.1 - 7.3e-07 29.1 2.0 7.3e-07 29.1 1.4 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMG48210.1 - 0.0003 20.8 2.2 0.00079 19.5 1.5 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EMG48210.1 - 0.0029 17.6 1.4 0.02 14.9 0.2 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 EMG48210.1 - 0.053 13.2 0.8 0.15 11.8 0.4 1.9 1 1 1 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.1 EMG48210.1 - 0.075 13.3 1.1 0.16 12.3 0.8 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger UCH PF00443.24 EMG48211.1 - 2.6e-51 174.3 2.8 6.5e-51 173.0 1.9 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMG48211.1 - 1.3e-23 83.8 7.7 1.9e-23 83.3 2.6 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_M48 PF01435.13 EMG48212.1 - 1.5e-30 106.4 0.0 2.7e-30 105.6 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M48 SKG6 PF08693.5 EMG48214.1 - 0.00093 18.4 0.0 0.0019 17.4 0.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1798 PF08807.5 EMG48214.1 - 0.0091 15.7 2.8 0.032 13.9 0.3 2.5 3 0 0 3 3 3 1 Bacterial domain of unknown function (DUF1798) DUF4017 PF13209.1 EMG48214.1 - 0.036 13.8 0.4 0.67 9.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4017) DUF3792 PF12670.2 EMG48214.1 - 0.046 13.5 0.1 0.061 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) YajC PF02699.10 EMG48214.1 - 0.075 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit MFS_1 PF07690.11 EMG48216.1 - 1.9e-22 79.4 7.4 1.9e-22 79.4 5.1 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.8 EMG48216.1 - 3.2e-17 62.6 2.6 3.2e-17 62.6 1.8 2.2 3 0 0 3 3 3 1 Nodulin-like Sugar_tr PF00083.19 EMG48216.1 - 1.5e-09 36.9 21.1 2.5e-05 23.0 3.3 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter Zds_C PF08632.5 EMG48217.1 - 1.7e-31 107.3 2.2 3.1e-31 106.5 1.6 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Cyt-b5 PF00173.23 EMG48218.1 - 1.3e-19 69.7 0.8 7.3e-19 67.3 0.0 2.4 2 1 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EMG48218.1 - 1.5e-10 41.4 20.1 6.8e-10 39.3 12.8 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily COX14 PF14880.1 EMG48218.1 - 1.8 8.2 6.1 14 5.3 1.7 3.0 3 0 0 3 3 3 0 Cytochrome oxidase c assembly JAB PF01398.16 EMG48219.1 - 1.6e-27 95.5 0.0 1.6e-27 95.5 0.0 2.2 3 0 0 3 3 3 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EMG48219.1 - 4.9e-08 32.4 0.0 1.3e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain BUD22 PF09073.5 EMG48219.1 - 0.16 10.9 19.0 0.24 10.4 13.2 1.3 1 0 0 1 1 1 0 BUD22 UPF0172 PF03665.8 EMG48219.1 - 0.37 10.2 2.8 1 8.7 0.0 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0172) UCH PF00443.24 EMG48220.1 - 1e-58 198.6 11.4 1e-58 198.6 7.9 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMG48220.1 - 2.7e-19 69.7 9.4 2.7e-19 69.7 6.5 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_M35 PF02102.10 EMG48220.1 - 0.014 14.0 0.2 0.022 13.4 0.1 1.2 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family SHR3_chaperone PF08229.6 EMG48221.1 - 3e-84 280.8 1.0 3e-84 280.8 0.7 1.4 1 1 1 2 2 2 1 ER membrane protein SH3 DUF808 PF05661.7 EMG48221.1 - 0.038 12.8 0.1 0.053 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF808) IncA PF04156.9 EMG48221.1 - 0.094 12.3 0.2 0.094 12.3 0.1 2.0 2 0 0 2 2 2 0 IncA protein DUF3290 PF11694.3 EMG48221.1 - 0.11 12.2 0.3 0.94 9.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) DUF2681 PF10883.3 EMG48221.1 - 0.26 11.4 3.2 0.55 10.4 2.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) NADHdh_A3 PF14987.1 EMG48222.1 - 0.015 15.1 0.2 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Ribosomal_L22 PF00237.14 EMG48223.1 - 1.1e-20 73.5 0.5 1.1e-20 73.5 0.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Peptidase_U32 PF01136.14 EMG48223.1 - 0.065 12.1 0.1 0.093 11.6 0.1 1.3 1 0 0 1 1 1 0 Peptidase family U32 Yippee-Mis18 PF03226.9 EMG48224.1 - 1.7e-11 44.0 1.0 1.7e-11 44.0 0.7 1.7 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Brix PF04427.13 EMG48225.1 - 1e-42 145.9 0.8 1.5e-42 145.4 0.6 1.2 1 0 0 1 1 1 1 Brix domain Pyr_redox_2 PF07992.9 EMG48226.1 - 3.6e-11 43.3 0.0 5.6e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMG48226.1 - 6.7e-07 29.6 0.0 0.00024 21.4 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMG48226.1 - 3.3e-06 26.9 0.2 0.091 12.5 0.0 3.3 3 1 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EMG48226.1 - 0.0018 18.3 0.0 0.02 14.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMG48226.1 - 0.0045 15.9 0.0 0.0083 15.0 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) U3_snoRNA_assoc PF08297.6 EMG48226.1 - 0.009 16.2 0.1 0.017 15.3 0.1 1.4 1 0 0 1 1 1 1 U3 snoRNA associated Pyr_redox PF00070.22 EMG48227.1 - 1.4e-09 38.2 0.0 1.4e-06 28.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMG48227.1 - 1.3e-06 28.6 0.0 0.02 14.9 0.0 3.1 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMG48227.1 - 7e-06 26.0 0.0 1.5e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMG48227.1 - 0.00029 19.8 0.0 0.00096 18.1 0.0 1.9 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EMG48227.1 - 0.0049 16.6 0.0 5.8 6.6 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 EMG48227.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus VTC PF09359.5 EMG48228.1 - 1.9e-102 342.1 0.2 3.5e-102 341.2 0.0 1.5 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 EMG48228.1 - 7.8e-22 78.3 15.9 1.5e-17 64.3 10.3 3.5 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 EMG48228.1 - 1.3e-13 50.9 5.1 2.4e-13 50.0 3.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MazG PF03819.12 EMG48228.1 - 0.0071 16.2 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain DUF3981 PF13139.1 EMG48228.1 - 0.11 12.5 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3981) LXG PF04740.7 EMG48228.1 - 0.32 10.7 11.0 1.2 8.8 0.4 3.2 2 1 2 4 4 4 0 LXG domain of WXG superfamily Polyketide_cyc2 PF10604.4 EMG48229.1 - 3.8e-05 23.8 0.0 5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Peptidase_S10 PF00450.17 EMG48230.1 - 2.8e-110 369.3 0.0 3.5e-110 369.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EMG48230.1 - 7.7e-05 22.6 0.0 0.00035 20.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DAO PF01266.19 EMG48231.1 - 1e-11 44.3 0.0 4.3e-11 42.3 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMG48231.1 - 0.023 14.7 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMG48231.1 - 0.083 12.7 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMG48231.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding IBN_N PF03810.14 EMG48232.1 - 0.00096 19.0 3.1 0.018 14.9 0.1 4.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EMG48232.1 - 0.0054 16.6 4.9 0.0054 16.6 3.4 5.3 5 2 0 5 5 5 1 Exportin 1-like protein RAP PF08373.5 EMG48235.1 - 0.039 13.7 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 RAP domain MKT1_C PF12246.3 EMG48237.1 - 4.9e-57 192.7 6.0 7.7e-57 192.0 4.1 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EMG48237.1 - 1.1e-33 115.4 1.4 3.8e-33 113.6 1.0 2.0 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 EMG48237.1 - 9.5e-14 51.2 0.0 2.7e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EMG48237.1 - 1.9e-13 50.5 1.9 7.6e-13 48.6 0.0 2.9 4 0 0 4 4 4 1 XPG N-terminal domain Gpi16 PF04113.9 EMG48238.1 - 1.3e-168 561.5 0.1 1.5e-168 561.3 0.1 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component SNARE PF05739.14 EMG48238.1 - 0.086 12.5 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 SNARE domain Elong_Iki1 PF10483.4 EMG48239.1 - 3.4e-87 292.3 4.5 3.8e-87 292.1 3.1 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 HEAT_2 PF13646.1 EMG48240.1 - 7.7e-12 45.3 0.4 0.31 11.3 0.0 7.0 4 3 4 8 8 8 5 HEAT repeats HEAT_EZ PF13513.1 EMG48240.1 - 2.6e-11 43.6 0.1 0.055 13.9 0.0 7.4 7 2 0 7 7 7 3 HEAT-like repeat HEAT PF02985.17 EMG48240.1 - 3.1e-10 39.2 7.5 0.25 11.5 0.0 9.4 10 0 0 10 10 10 2 HEAT repeat Vac14_Fab1_bd PF12755.2 EMG48240.1 - 2.3e-08 34.2 8.7 4 7.8 0.0 7.7 5 2 0 7 7 7 3 Vacuolar 14 Fab1-binding region SF3b1 PF08920.5 EMG48240.1 - 0.00017 21.6 7.8 0.0079 16.2 5.4 2.4 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 MMS19_C PF12460.3 EMG48240.1 - 0.085 11.5 0.0 0.085 11.5 0.0 5.6 5 1 0 6 6 6 0 RNAPII transcription regulator C-terminal RED_C PF07807.6 EMG48241.1 - 0.019 15.1 0.1 0.044 13.9 0.1 1.6 1 0 0 1 1 1 0 RED-like protein C-terminal region MAGE PF01454.14 EMG48242.1 - 2.2e-32 112.0 0.8 5.4e-32 110.7 0.2 1.7 1 1 1 2 2 2 1 MAGE family TetR_C_7 PF14246.1 EMG48242.1 - 0.084 13.0 0.1 0.28 11.4 0.0 2.0 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal region FAD_binding_1 PF00667.15 EMG48243.1 - 1.2e-74 250.4 0.0 1.8e-74 249.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EMG48243.1 - 7.7e-33 113.5 0.5 1.4e-32 112.6 0.4 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EMG48243.1 - 2.3e-23 82.8 0.1 2.5e-22 79.4 0.0 2.5 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Ins_P5_2-kin PF06090.7 EMG48244.1 - 5.1e-79 265.5 9.0 7.5e-79 264.9 6.2 1.3 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase AIM24 PF01987.12 EMG48244.1 - 7.7e-06 25.5 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 VirB8 PF04335.8 EMG48244.1 - 0.15 11.6 0.1 0.38 10.2 0.0 1.6 1 0 0 1 1 1 0 VirB8 protein DUF3757 PF12582.3 EMG48244.1 - 0.43 10.7 1.7 0.65 10.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3757) Mad3_BUB1_I PF08311.7 EMG48247.1 - 2.3e-43 146.9 1.8 4.7e-43 145.9 1.3 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EMG48247.1 - 6.5e-19 68.0 0.0 1.1e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Mad3_BUB1_II PF08171.6 EMG48247.1 - 3.5e-18 65.2 0.0 3.5e-18 65.2 0.0 3.2 4 0 0 4 4 4 1 Mad3/BUB1 homology region 2 Pkinase_Tyr PF07714.12 EMG48247.1 - 0.001 18.1 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Hydrolase PF00702.21 EMG48248.1 - 6.9e-19 69.1 0.1 3.6e-17 63.5 0.1 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EMG48248.1 - 2.9e-16 59.2 0.0 6.9e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EMG48248.1 - 2.8e-14 53.7 4.0 6.7e-13 49.2 2.8 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMG48248.1 - 1.6e-12 47.1 0.0 6.9e-12 45.1 0.0 2.2 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMG48248.1 - 0.0014 18.2 0.1 0.0014 18.2 0.1 4.1 5 0 0 5 5 5 1 haloacid dehalogenase-like hydrolase AA_permease PF00324.16 EMG48249.1 - 1.7e-14 53.0 5.4 2e-14 52.7 3.8 1.0 1 0 0 1 1 1 1 Amino acid permease UPF0261 PF06792.6 EMG48249.1 - 0.14 10.6 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) Ribonuclease_T2 PF00445.13 EMG48250.1 - 3.3e-31 108.3 1.9 4.6e-31 107.9 1.3 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family PGAMP PF07644.6 EMG48250.1 - 0.078 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Planctomycete PGAMP DUF1684 PF07920.6 EMG48252.1 - 0.041 13.7 0.5 0.041 13.7 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1684) TMF_DNA_bd PF12329.3 EMG48253.1 - 0.00012 21.7 9.4 0.00012 21.7 6.5 8.2 2 1 4 8 8 8 4 TATA element modulatory factor 1 DNA binding Kinetocho_Slk19 PF12709.2 EMG48253.1 - 0.0084 16.1 14.0 0.0084 16.1 9.7 8.4 1 1 8 9 9 9 2 Central kinetochore-associated gpW PF02831.10 EMG48253.1 - 0.045 13.3 1.0 0.26 10.8 0.2 2.7 2 0 0 2 2 2 0 gpW Reo_sigmaC PF04582.7 EMG48253.1 - 5.3 6.1 26.1 5.1 6.1 0.9 4.3 1 1 4 5 5 5 0 Reovirus sigma C capsid protein TFIIA PF03153.8 EMG48254.1 - 1.7e-41 143.4 26.0 5.1e-24 85.8 1.6 2.2 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit CENP-T PF15511.1 EMG48254.1 - 9.3 5.3 8.9 13 4.9 6.2 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T He_PIG PF05345.7 EMG48255.1 - 2e-16 59.7 16.8 1.2e-08 34.8 1.5 5.2 4 0 0 4 4 4 3 Putative Ig domain SKG6 PF08693.5 EMG48255.1 - 4.5e-07 29.0 0.2 4.5e-07 29.0 0.1 2.2 2 0 0 2 2 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 EMG48255.1 - 1.9e-06 27.6 0.2 7e-06 25.8 0.1 2.0 1 0 0 1 1 1 1 TMEM154 protein family Mid2 PF04478.7 EMG48255.1 - 2.1e-06 27.2 0.8 2.1e-06 27.2 0.6 2.3 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor DUF4448 PF14610.1 EMG48255.1 - 0.00015 21.3 0.1 0.0006 19.3 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) DUF1517 PF07466.6 EMG48255.1 - 0.00015 20.8 0.5 0.00032 19.8 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) DAG1 PF05454.6 EMG48255.1 - 0.0022 17.2 0.2 0.0053 15.9 0.1 1.6 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Podoplanin PF05808.6 EMG48255.1 - 0.013 15.0 1.2 0.013 15.0 0.8 2.5 2 0 0 2 2 2 0 Podoplanin Rifin_STEVOR PF02009.11 EMG48255.1 - 0.018 14.7 0.2 0.041 13.5 0.1 1.6 1 0 0 1 1 1 0 Rifin/stevor family DUF912 PF06024.7 EMG48255.1 - 0.022 14.8 0.3 0.14 12.1 0.0 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EphA2_TM PF14575.1 EMG48255.1 - 0.031 14.6 0.0 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 EMG48255.1 - 0.12 12.4 2.8 0.25 11.4 1.2 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Peptidase_M56 PF05569.6 EMG48255.1 - 0.27 10.1 0.0 0.52 9.2 0.0 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 MLANA PF14991.1 EMG48255.1 - 8.3 6.4 7.5 1.4 8.9 0.6 2.5 1 1 1 2 2 2 0 Protein melan-A 4HBT PF03061.17 EMG48256.1 - 6.6e-05 22.9 0.2 0.067 13.3 0.0 2.8 2 1 0 2 2 2 2 Thioesterase superfamily DUF4119 PF13494.1 EMG48256.1 - 0.08 12.9 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) Transket_pyr PF02779.19 EMG48257.1 - 1.5e-44 151.5 0.0 2.4e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EMG48257.1 - 9.3e-38 128.9 0.0 3e-37 127.3 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain FAD_binding_8 PF08022.7 EMG48258.1 - 6.3e-24 83.8 0.0 1.1e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EMG48258.1 - 1e-17 64.3 9.6 1e-17 64.3 6.6 2.5 2 1 0 2 2 2 1 Ferric reductase like transmembrane component DUF2207 PF09972.4 EMG48258.1 - 0.34 9.4 4.2 0.099 11.2 0.6 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DAGK_cat PF00781.19 EMG48260.1 - 2.7e-08 33.3 0.0 4.2e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain XRN_N PF03159.13 EMG48261.1 - 8.9e-109 362.4 0.7 3.2e-108 360.6 0.0 2.2 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus DUF1635 PF07795.6 EMG48261.1 - 0.44 9.8 5.9 0.98 8.7 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) AA_permease PF00324.16 EMG48262.1 - 1.1e-17 63.5 7.7 1.3e-17 63.3 5.3 1.0 1 0 0 1 1 1 1 Amino acid permease DASH_Ask1 PF08655.5 EMG48264.1 - 1e-31 108.5 0.6 3.9e-31 106.6 0.2 2.0 2 0 0 2 2 2 1 DASH complex subunit Ask1 SBF2 PF12335.3 EMG48264.1 - 2.7 7.2 6.7 0.17 11.2 0.8 1.7 2 0 0 2 2 2 0 Myotubularin protein UPF0203 PF05254.7 EMG48265.1 - 4.5e-30 103.3 0.8 5.7e-30 102.9 0.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 EMG48265.1 - 0.00042 20.0 3.4 0.11 12.3 0.1 2.4 2 1 1 3 3 3 2 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 EMG48265.1 - 0.059 13.3 0.6 0.14 12.1 0.4 1.6 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Lipase_3 PF01764.20 EMG48266.1 - 3.8e-17 62.2 0.0 7e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) zf-HIT PF04438.11 EMG48266.1 - 0.84 9.3 15.3 0.1 12.2 7.1 2.0 2 0 0 2 2 2 0 HIT zinc finger NAD_binding_9 PF13454.1 EMG48267.1 - 5.8e-05 22.9 0.0 0.00026 20.7 0.0 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EMG48267.1 - 7.1e-05 22.9 0.0 0.013 15.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMG48267.1 - 0.00015 21.7 0.0 0.00047 20.1 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Atg31 PF09795.4 EMG48267.1 - 0.025 14.3 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 Autophagy-related protein 31 NAD_binding_8 PF13450.1 EMG48267.1 - 0.066 13.2 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Aminotran_1_2 PF00155.16 EMG48268.1 - 5.4e-64 216.4 0.0 6.1e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II zf-C2H2 PF00096.21 EMG48269.1 - 2.3e-10 40.2 11.5 5.2e-06 26.4 1.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMG48269.1 - 7.3e-08 32.2 15.4 0.00036 20.6 0.8 2.9 3 0 0 3 3 2 2 C2H2-type zinc finger zf-met PF12874.2 EMG48269.1 - 1.3e-07 31.5 4.6 0.0059 16.7 0.2 3.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EMG48269.1 - 2.8e-07 30.4 18.6 1.3e-06 28.3 3.6 3.3 3 0 0 3 3 3 2 Zinc-finger double domain RRN7 PF11781.3 EMG48269.1 - 0.036 13.5 1.5 0.81 9.2 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_jaz PF12171.3 EMG48269.1 - 0.039 14.0 16.6 0.11 12.7 1.1 3.3 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding Elf1 PF05129.8 EMG48269.1 - 0.062 12.9 7.0 0.18 11.5 4.8 1.8 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-Di19 PF05605.7 EMG48269.1 - 0.071 13.2 4.5 0.15 12.2 3.1 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 EMG48269.1 - 0.085 12.9 0.4 0.085 12.9 0.3 3.3 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn_Tnp_IS1595 PF12760.2 EMG48269.1 - 0.14 12.0 4.2 0.31 10.8 2.9 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EMG48269.1 - 0.15 12.0 3.0 12 5.9 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain LIM PF00412.17 EMG48269.1 - 0.31 11.1 3.4 0.66 10.0 2.4 1.5 1 0 0 1 1 1 0 LIM domain zf-BED PF02892.10 EMG48269.1 - 0.55 10.0 9.5 1.6 8.5 1.7 2.5 1 1 1 2 2 2 0 BED zinc finger zf-LYAR PF08790.6 EMG48269.1 - 0.75 9.5 3.4 1.5 8.5 0.1 2.7 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.1 EMG48269.1 - 0.85 9.6 15.1 0.19 11.6 0.4 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Zn_Tnp_IS1 PF03811.8 EMG48269.1 - 1.4 8.4 5.5 3.5 7.1 3.8 1.7 1 0 0 1 1 1 0 InsA N-terminal domain PAT1 PF09770.4 EMG48269.1 - 4.8 5.2 62.4 1.5 6.9 27.8 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 SRF-TF PF00319.13 EMG48270.1 - 3.4e-22 77.4 0.1 5.7e-22 76.6 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ribosomal_S6e PF01092.14 EMG48271.1 - 4.7e-65 216.9 0.5 8.2e-65 216.1 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e PRP21_like_P PF12230.3 EMG48272.1 - 2.7e-59 200.4 9.1 5.1e-59 199.5 6.3 1.4 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EMG48272.1 - 3.7e-31 106.5 2.2 3.5e-17 61.8 0.2 2.7 2 0 0 2 2 2 2 Surp module VPS11_C PF12451.3 EMG48272.1 - 0.34 10.7 4.0 3.1 7.7 0.1 3.8 2 1 1 3 3 3 0 Vacuolar protein sorting protein 11 C terminal zinc_ribbon_6 PF14599.1 EMG48273.1 - 2.6e-24 84.7 1.1 2.6e-24 84.7 0.7 4.8 4 2 2 6 6 6 1 Zinc-ribbon zf-CHY PF05495.7 EMG48273.1 - 4.6e-14 52.3 23.1 4.6e-14 52.3 16.0 4.5 3 1 0 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.1 EMG48273.1 - 2.9e-07 30.2 10.7 2.9e-07 30.2 7.4 5.2 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMG48273.1 - 4e-07 29.6 10.5 4e-07 29.6 7.3 5.9 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMG48273.1 - 1.2e-05 25.2 12.5 1.2e-05 25.2 8.7 5.7 5 1 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMG48273.1 - 0.00011 21.8 12.6 0.00011 21.8 8.7 5.8 3 2 2 5 5 5 1 zinc-RING finger domain NIF PF03031.13 EMG48274.1 - 3.4e-47 160.0 1.2 3.4e-47 160.0 0.8 2.1 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase Kei1 PF08552.6 EMG48274.1 - 0.084 12.5 0.3 0.16 11.5 0.2 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Daxx PF03344.10 EMG48274.1 - 0.51 8.7 15.1 1.5 7.1 10.7 1.4 1 1 0 1 1 1 0 Daxx Family GAGA_bind PF06217.7 EMG48274.1 - 0.7 9.7 4.8 1.4 8.8 3.3 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2422 PF10337.4 EMG48274.1 - 2.3 6.8 3.8 3.6 6.2 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) FTCD_C PF04961.7 EMG48274.1 - 4.5 6.6 5.1 7 6.0 3.6 1.2 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase DUF2528 PF10800.3 EMG48275.1 - 0.031 14.6 0.1 0.093 13.1 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2528) Acetyltransf_1 PF00583.19 EMG48277.1 - 1e-10 41.4 0.0 1.6e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMG48277.1 - 3.4e-08 33.5 0.1 5.3e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMG48277.1 - 0.00062 19.8 0.0 0.0012 19.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain NPR3 PF03666.8 EMG48278.1 - 0.014 13.9 3.4 0.018 13.6 2.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF572 PF04502.8 EMG48278.1 - 0.037 13.2 3.7 0.04 13.1 2.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DNA_pol_viral_N PF00242.12 EMG48278.1 - 0.098 11.6 3.9 0.1 11.6 2.7 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Mucin PF01456.12 EMG48278.1 - 0.3 10.8 16.1 0.6 9.8 11.2 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Peptidase_C24 PF03510.9 EMG48278.1 - 0.52 10.5 6.4 0.17 12.0 1.2 1.9 1 1 1 2 2 2 0 2C endopeptidase (C24) cysteine protease family Macoilin PF09726.4 EMG48278.1 - 1.1 7.4 7.3 1.3 7.2 5.1 1.0 1 0 0 1 1 1 0 Transmembrane protein ALS_ss_C PF10369.4 EMG48279.1 - 1.6e-18 66.2 0.0 6.2e-18 64.2 0.0 2.0 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 EMG48279.1 - 1.7e-11 43.3 0.1 3.7e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EMG48279.1 - 2.4e-06 27.2 0.0 4.6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 ACT domain Zn_clus PF00172.13 EMG48280.1 - 1.8e-08 34.1 11.5 3.1e-08 33.3 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 EMG48282.1 - 4.7e-84 282.7 0.0 5.5e-84 282.5 0.0 1.0 1 0 0 1 1 1 1 Amidase OPT PF03169.10 EMG48283.1 - 7e-165 549.9 41.1 8e-165 549.7 28.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4083 PF13314.1 EMG48284.1 - 0.0033 17.2 1.5 0.0073 16.1 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4083) HH_signal PF01085.13 EMG48285.1 - 0.05 13.1 1.0 0.078 12.5 0.7 1.2 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain SR-25 PF10500.4 EMG48285.1 - 0.1 12.0 17.3 0.28 10.6 3.3 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SH3_1 PF00018.23 EMG48286.1 - 1e-22 79.2 0.3 2.5e-11 42.7 0.2 3.1 2 1 0 2 2 2 2 SH3 domain PX PF00787.19 EMG48286.1 - 3.1e-13 49.5 0.1 8e-13 48.1 0.0 1.8 1 0 0 1 1 1 1 PX domain SH3_9 PF14604.1 EMG48286.1 - 3.6e-13 48.8 0.1 4.4e-09 35.7 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EMG48286.1 - 3.9e-09 35.8 0.0 1.4e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain CBFD_NFYB_HMF PF00808.18 EMG48287.1 - 9.3e-21 73.6 0.1 1.6e-20 72.9 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMG48287.1 - 0.026 14.6 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EMG48287.1 - 0.028 14.2 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit NMT PF01233.14 EMG48290.1 - 5.7e-82 273.1 0.1 8.3e-82 272.6 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EMG48290.1 - 3.9e-77 257.9 0.6 6.4e-77 257.2 0.4 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_7 PF13508.1 EMG48290.1 - 0.019 15.1 0.0 0.057 13.5 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Candida_ALS_N PF11766.3 EMG48293.1 - 1.1e-80 270.0 7.2 1.1e-80 270.0 5.0 1.5 2 0 0 2 2 2 1 Cell-wall agglutinin N-terminal ligand-sugar binding Candida_ALS PF05792.8 EMG48293.1 - 0.00044 20.3 19.9 0.00044 20.3 13.8 5.3 6 0 0 6 6 6 1 Candida agglutinin-like (ALS) F-box-like PF12937.2 EMG48295.1 - 2.1e-05 24.1 0.4 4.4e-05 23.1 0.3 1.6 1 0 0 1 1 1 1 F-box-like MIT PF04212.13 EMG48295.1 - 0.0048 16.7 0.2 0.013 15.3 0.1 1.7 1 1 0 1 1 1 1 MIT (microtubule interacting and transport) domain Thioredoxin_4 PF13462.1 EMG48296.1 - 5.1e-09 36.3 0.0 1.7e-08 34.6 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EMG48296.1 - 0.02 15.1 0.0 0.04 14.1 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain WASH-7_mid PF14744.1 EMG48296.1 - 0.044 12.6 0.1 0.059 12.2 0.1 1.2 1 0 0 1 1 1 0 WASH complex subunit 7 WD40 PF00400.27 EMG48297.1 - 7.2e-16 57.3 10.9 4.1e-05 23.2 0.6 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 EMG48297.1 - 0.013 13.6 3.1 0.021 13.0 2.1 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EMG48297.1 - 0.015 15.5 0.0 0.13 12.5 0.0 2.4 2 0 0 2 2 2 0 PQQ-like domain DUF89 PF01937.14 EMG48298.1 - 3.9e-118 394.2 2.2 4.5e-118 394.1 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 eIF-3c_N PF05470.7 EMG48299.1 - 8.1e-141 470.0 17.9 2e-111 372.9 1.5 3.4 3 1 1 4 4 4 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EMG48299.1 - 4.3e-09 36.6 0.9 3.5e-08 33.7 0.1 2.9 3 0 0 3 3 3 1 PCI domain DUF4175 PF13779.1 EMG48299.1 - 2.2 5.8 36.1 3.7 5.1 25.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Band_3_cyto PF07565.8 EMG48299.1 - 8.2 5.8 14.7 4.6 6.6 7.8 2.4 3 0 0 3 3 3 0 Band 3 cytoplasmic domain Candida_ALS PF05792.8 EMG48300.1 - 9.4e-14 51.2 40.6 5.1e-11 42.4 12.6 9.7 9 3 0 9 9 9 2 Candida agglutinin-like (ALS) TAP42 PF04177.7 EMG48301.1 - 7.8e-87 291.3 7.3 8.8e-87 291.2 5.1 1.0 1 0 0 1 1 1 1 TAP42-like family Nup160 PF11715.3 EMG48302.1 - 5.2e-72 242.7 8.4 7.7e-72 242.1 5.8 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DWNN PF08783.6 EMG48303.1 - 1.3e-27 95.4 0.2 1.3e-27 95.4 0.1 2.6 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.1 EMG48303.1 - 4.9e-05 22.7 3.8 0.00011 21.6 2.6 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EMG48303.1 - 5.2e-05 22.9 8.1 0.00012 21.8 1.8 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.1 EMG48303.1 - 0.018 14.4 0.7 0.018 14.4 0.5 2.8 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.1 EMG48303.1 - 0.026 14.2 0.1 0.071 12.8 0.1 1.8 1 0 0 1 1 1 0 Zinc knuckle Zn_Tnp_IS1595 PF12760.2 EMG48303.1 - 0.028 14.2 0.4 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF1610 PF07754.6 EMG48303.1 - 7.2 6.8 7.3 0.96 9.6 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Bul1_N PF04425.7 EMG48304.1 - 2.9e-146 487.5 5.6 2.9e-146 487.5 3.9 2.4 1 1 1 2 2 2 1 Bul1 N terminus CPSase_sm_chain PF00988.17 EMG48304.1 - 1.9e-45 153.5 0.0 4.4e-45 152.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EMG48304.1 - 3.7e-45 153.7 0.0 6.4e-45 152.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Bul1_C PF04426.7 EMG48304.1 - 3.6e-11 42.7 7.7 2.5e-07 30.1 0.9 3.0 2 1 1 3 3 3 2 Bul1 C terminus Peptidase_C26 PF07722.8 EMG48304.1 - 0.00011 21.7 0.3 0.0027 17.1 0.2 2.5 1 1 0 1 1 1 1 Peptidase C26 FA_hydroxylase PF04116.8 EMG48305.1 - 2.7e-15 56.7 18.2 2.7e-15 56.7 12.6 2.2 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily VirB3 PF05101.8 EMG48305.1 - 2 8.4 6.8 0.71 9.8 0.1 2.8 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein Ribosomal_L18ae PF01775.12 EMG48306.1 - 1.7e-56 189.4 0.8 2.4e-56 188.9 0.6 1.2 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain adh_short PF00106.20 EMG48307.1 - 3.1e-29 102.0 0.0 5e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMG48307.1 - 5.7e-13 49.1 0.0 7.4e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMG48307.1 - 1.4e-10 41.0 0.0 2.3e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMG48307.1 - 5.1e-05 22.8 0.1 0.00016 21.2 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMG48307.1 - 0.002 17.1 0.0 0.0027 16.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EMG48307.1 - 0.0099 15.6 0.1 0.022 14.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase LIX1 PF14954.1 EMG48307.1 - 0.058 12.3 0.0 0.09 11.7 0.0 1.2 1 0 0 1 1 1 0 Limb expression 1 NAD_binding_10 PF13460.1 EMG48307.1 - 0.08 12.9 0.2 1 9.3 0.1 2.1 2 0 0 2 2 2 0 NADH(P)-binding ATP_bind_3 PF01171.15 EMG48308.1 - 8.3e-19 67.7 0.0 2e-18 66.5 0.0 1.7 1 1 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 EMG48308.1 - 0.0029 17.9 0.0 0.007 16.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 EMG48308.1 - 0.024 13.1 0.5 0.068 11.7 0.0 1.9 2 1 0 2 2 2 0 tRNA methyl transferase Asn_synthase PF00733.16 EMG48308.1 - 0.04 13.3 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase zf-CCHC_4 PF14392.1 EMG48308.1 - 0.56 9.9 3.9 21 4.8 0.0 3.6 3 0 0 3 3 3 0 Zinc knuckle DUF3970 PF13113.1 EMG48308.1 - 0.63 9.7 3.8 0.28 10.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3970) Cytochrom_c3_2 PF14537.1 EMG48308.1 - 4.6 7.6 9.1 1.6 9.1 0.2 2.5 2 0 0 2 2 2 0 Cytochrome c3 DZR PF12773.2 EMG48308.1 - 6.8 6.5 10.7 8.8 6.2 0.3 3.1 3 0 0 3 3 3 0 Double zinc ribbon CUE PF02845.11 EMG48309.1 - 3.2e-07 29.7 0.4 6.1e-07 28.8 0.3 1.5 1 0 0 1 1 1 1 CUE domain HMG_box PF00505.14 EMG48310.1 - 4.7e-26 90.8 0.9 4.7e-26 90.8 0.6 1.4 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMG48310.1 - 3.7e-19 68.8 1.8 3.9e-19 68.7 0.9 1.3 1 1 0 1 1 1 1 HMG-box domain CHDNT PF08073.7 EMG48310.1 - 0.0039 16.8 0.0 0.0063 16.1 0.0 1.2 1 0 0 1 1 1 1 CHDNT (NUC034) domain HMG_box_5 PF14887.1 EMG48310.1 - 0.0059 16.3 1.4 0.0059 16.3 1.0 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 EMG48310.1 - 0.0078 16.4 1.6 0.023 14.9 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1014) F_bP_aldolase PF01116.15 EMG48311.1 - 4.4e-97 324.6 0.0 5e-97 324.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II zf-Tim10_DDP PF02953.10 EMG48312.1 - 2e-15 55.8 0.3 2.4e-15 55.5 0.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EMG48312.1 - 0.071 12.5 0.1 0.094 12.1 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) TTL PF03133.10 EMG48313.1 - 2.7e-60 203.7 0.4 4.4e-60 203.0 0.3 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 EMG48313.1 - 1.1e-41 142.3 0.0 1.8e-41 141.6 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATP-grasp_4 PF13535.1 EMG48313.1 - 0.00014 21.6 0.1 0.0017 18.1 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain Nro1 PF12753.2 EMG48313.1 - 0.0012 17.8 0.6 0.002 17.1 0.4 1.3 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 ATPgrasp_YheCD PF14398.1 EMG48313.1 - 0.0013 17.5 0.0 0.025 13.3 0.0 2.2 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_Ter PF15632.1 EMG48313.1 - 0.16 10.6 0.1 0.43 9.2 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon BSD PF03909.12 EMG48314.1 - 2.2e-23 81.7 9.1 5.9e-13 48.3 0.0 3.1 3 0 0 3 3 3 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EMG48314.1 - 1.4e-15 56.6 0.0 2.9e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Acetyltransf_1 PF00583.19 EMG48315.1 - 1.3e-12 47.5 0.0 2e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMG48315.1 - 1.9e-08 34.3 0.0 2.9e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EMG48315.1 - 7e-08 32.4 0.0 8.5e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMG48315.1 - 6e-07 29.7 0.0 7.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMG48315.1 - 6e-06 25.9 0.1 1e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EMG48315.1 - 6.3e-05 23.0 0.0 8.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMG48315.1 - 0.0021 18.0 0.2 0.0026 17.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMG48315.1 - 0.0044 16.8 0.0 0.008 16.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMG48315.1 - 0.073 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Coa1 PF08695.5 EMG48316.1 - 2.7e-40 136.5 0.0 3.4e-40 136.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 GP41 PF00517.12 EMG48317.1 - 0.015 14.8 0.4 0.026 14.1 0.0 1.6 2 0 0 2 2 2 0 Retroviral envelope protein Thioredoxin_8 PF13905.1 EMG48317.1 - 0.032 14.3 2.6 0.35 10.9 0.1 2.9 2 1 1 3 3 3 0 Thioredoxin-like DUF843 PF05814.6 EMG48317.1 - 0.1 12.4 0.2 0.1 12.4 0.1 2.4 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Sigma_reg_N PF13800.1 EMG48317.1 - 0.13 12.2 2.3 0.35 10.9 1.6 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal ODV-E18 PF10717.4 EMG48317.1 - 4.6 6.7 6.2 25 4.3 4.3 2.3 1 1 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Prenyltrans PF00432.16 EMG48318.1 - 1.7e-30 104.2 1.6 5.7e-06 25.7 0.0 5.5 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EMG48318.1 - 1.7e-16 60.6 0.0 9.5e-11 42.1 0.0 3.5 2 1 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EMG48318.1 - 0.014 15.3 0.0 1.1 9.3 0.0 3.1 2 1 2 4 4 4 0 Prenyltransferase-like APG6 PF04111.7 EMG48319.1 - 0.0022 17.1 13.5 0.0022 17.1 9.4 3.1 1 1 1 3 3 3 1 Autophagy protein Apg6 ALMT PF11744.3 EMG48319.1 - 4.7 5.7 7.3 6.5 5.2 5.1 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2418 PF10332.4 EMG48320.1 - 9.2e-30 102.8 2.8 9.2e-30 102.8 1.9 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2418) Gemini_AL2 PF01440.11 EMG48320.1 - 0.17 11.9 9.6 0.47 10.5 0.1 2.6 2 1 0 2 2 2 0 Geminivirus AL2 protein PROL5-SMR PF15621.1 EMG48320.1 - 7.9 6.9 21.5 1 9.7 11.2 2.3 1 1 1 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family Nup35_RRM PF05172.8 EMG48321.1 - 6.2e-22 77.2 0.3 1.5e-21 75.9 0.2 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EMG48321.1 - 6.5e-07 29.0 0.0 1.6e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RXT2_N PF08595.6 EMG48322.1 - 4.4e-40 136.9 4.0 4.4e-40 136.9 2.8 2.3 2 0 0 2 2 2 1 RXT2-like, N-terminal Rab5-bind PF09311.6 EMG48322.1 - 0.028 14.3 2.2 0.075 12.9 1.5 1.6 1 0 0 1 1 1 0 Rabaptin-like protein PCNA_C PF02747.10 EMG48323.1 - 6.3e-41 139.2 0.1 9.8e-41 138.6 0.1 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 EMG48323.1 - 2.4e-35 120.8 2.2 4.8e-32 110.1 0.3 3.0 2 1 1 3 3 3 2 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.11 EMG48323.1 - 2.1e-07 29.9 2.3 1.3e-05 24.1 1.6 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 EMG48323.1 - 0.00029 20.0 0.1 0.00034 19.8 0.1 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 EMG48323.1 - 0.014 14.3 0.0 0.91 8.4 0.1 2.2 1 1 1 2 2 2 0 Hus1-like protein FOP_dimer PF09398.5 EMG48323.1 - 0.082 12.9 0.4 0.17 11.9 0.3 1.5 1 0 0 1 1 1 0 FOP N terminal dimerisation domain Calreticulin PF00262.13 EMG48324.1 - 2.6e-106 355.3 7.3 8.5e-82 274.7 0.1 2.3 1 1 1 2 2 2 2 Calreticulin family Alb1 PF09135.6 EMG48325.1 - 1.7e-27 96.2 16.4 1.7e-27 96.2 11.4 1.7 2 0 0 2 2 2 1 Alb1 DUF1016 PF06250.6 EMG48325.1 - 0.031 13.2 7.9 0.047 12.6 5.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1016) Ribosomal_S13 PF00416.17 EMG48325.1 - 3.8 8.0 9.6 1.2 9.6 1.2 2.3 1 1 1 2 2 2 0 Ribosomal protein S13/S18 Abhydrolase_5 PF12695.2 EMG48328.1 - 2.2e-09 37.2 0.0 3.3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMG48328.1 - 6.1e-09 36.0 0.0 1.1e-08 35.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMG48328.1 - 0.00028 20.6 0.5 0.0026 17.5 0.1 2.5 3 0 0 3 3 3 1 Putative lysophospholipase BAAT_C PF08840.6 EMG48328.1 - 0.00028 20.6 0.0 0.00043 20.0 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 EMG48328.1 - 0.079 12.4 0.1 2.2 7.8 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold bZIP_2 PF07716.10 EMG48329.1 - 3.3e-09 36.4 8.2 3.3e-09 36.4 5.7 2.4 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.16 EMG48329.1 - 0.0005 19.9 7.8 0.0014 18.5 5.4 1.8 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.13 EMG48329.1 - 0.16 11.9 6.0 0.14 12.1 1.8 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family SR-25 PF10500.4 EMG48329.1 - 0.16 11.3 9.3 0.27 10.6 6.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Exo_endo_phos PF03372.18 EMG48330.1 - 1.6e-08 34.8 0.5 2.3e-08 34.2 0.4 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PT PF04886.7 EMG48332.1 - 1e-07 31.0 22.1 1e-07 31.0 15.3 2.7 2 1 1 3 3 3 1 PT repeat CT47 PF15623.1 EMG48332.1 - 0.096 12.4 22.6 0.14 11.8 15.7 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 DUF2283 PF10049.4 EMG48332.1 - 0.097 12.5 4.2 0.094 12.5 0.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2283) IER PF05760.7 EMG48332.1 - 0.33 10.8 6.2 0.41 10.5 4.3 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) Pneumo_att_G PF05539.6 EMG48332.1 - 1 8.6 6.8 1.4 8.1 4.7 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G MCPVI PF02993.9 EMG48332.1 - 1.1 9.3 7.0 1.5 8.8 4.9 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Menin PF05053.8 EMG48332.1 - 5 5.1 6.3 6.7 4.7 4.3 1.1 1 0 0 1 1 1 0 Menin RR_TM4-6 PF06459.7 EMG48332.1 - 5.7 6.7 10.0 7.4 6.3 6.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CAF1A PF12253.3 EMG48333.1 - 3.2e-25 88.0 11.1 3.2e-25 88.0 7.7 3.8 2 1 1 3 3 3 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 EMG48333.1 - 1.5e-11 44.1 79.8 1.5e-11 44.1 55.3 2.5 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Mucin PF01456.12 EMG48333.1 - 0.82 9.4 13.7 2.1 8.1 9.5 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein CPSase_L_D2 PF02786.12 EMG48334.1 - 1.7e-79 265.9 0.1 2.7e-79 265.3 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EMG48334.1 - 1.9e-65 219.9 0.0 3.4e-65 219.1 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EMG48334.1 - 9e-36 122.3 0.1 2.3e-35 121.0 0.0 1.8 2 0 0 2 2 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EMG48334.1 - 5.6e-30 103.4 0.0 1.2e-29 102.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EMG48334.1 - 9.5e-24 84.3 0.0 2.1e-23 83.2 0.0 1.6 1 0 0 1 1 1 1 HMGL-like ATPgrasp_Ter PF15632.1 EMG48334.1 - 2.1e-17 62.8 0.0 2.2e-16 59.5 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 EMG48334.1 - 4.6e-16 58.2 1.1 4.6e-16 58.2 0.8 2.6 3 0 0 3 3 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EMG48334.1 - 1.2e-14 54.4 0.2 3.4e-14 52.9 0.1 1.8 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EMG48334.1 - 3.3e-09 36.2 0.0 0.00027 20.5 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EMG48334.1 - 9.5e-08 31.6 0.0 1.9e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EMG48334.1 - 2.9e-06 26.7 0.0 5.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EMG48334.1 - 8.5e-05 22.4 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EMG48334.1 - 0.00016 21.2 0.0 0.022 14.2 0.0 2.3 2 0 0 2 2 2 1 RimK-like ATP-grasp domain HlyD PF00529.15 EMG48334.1 - 0.0052 16.1 0.0 1.3 8.2 0.0 2.3 2 0 0 2 2 2 2 HlyD family secretion protein PYNP_C PF07831.8 EMG48334.1 - 0.038 13.4 0.8 0.84 9.1 0.0 2.8 3 0 0 3 3 3 0 Pyrimidine nucleoside phosphorylase C-terminal domain GCV_H PF01597.14 EMG48334.1 - 0.053 13.2 2.9 3.6 7.2 0.1 3.0 2 1 1 3 3 2 0 Glycine cleavage H-protein GCR1_C PF12550.3 EMG48336.1 - 5.3e-15 55.0 2.5 5.3e-15 55.0 1.7 2.3 2 1 1 3 3 3 1 Transcriptional activator of glycolytic enzymes LRR_8 PF13855.1 EMG48337.1 - 3.6e-13 49.0 38.0 9.5e-09 34.8 0.2 7.6 6 2 2 8 8 8 5 Leucine rich repeat LRR_4 PF12799.2 EMG48337.1 - 6.4e-12 44.8 48.0 0.00049 19.6 0.0 9.6 7 2 3 10 10 10 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMG48337.1 - 2.2e-08 33.0 31.6 0.63 10.2 0.6 9.8 8 1 1 9 9 9 4 Leucine Rich Repeat F-box PF00646.28 EMG48337.1 - 0.049 13.3 0.2 0.21 11.3 0.1 2.2 1 0 0 1 1 1 0 F-box domain FNIP PF05725.7 EMG48337.1 - 1.2 9.1 27.1 8.5 6.4 0.1 8.9 9 2 1 10 10 10 0 FNIP Repeat LRR_7 PF13504.1 EMG48337.1 - 1.3 9.5 33.1 13 6.5 0.0 10.0 10 1 0 10 10 10 0 Leucine rich repeat LRR_6 PF13516.1 EMG48337.1 - 5.9 7.2 34.3 1.3 9.2 0.0 9.3 9 1 1 10 10 10 0 Leucine Rich repeat Sugar_tr PF00083.19 EMG48338.1 - 5.8e-41 140.5 24.5 1e-40 139.6 17.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG48338.1 - 1e-35 123.1 42.4 9.3e-30 103.5 17.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG11 PF10377.4 EMG48339.1 - 3.5e-35 120.7 0.4 3.5e-35 120.7 0.3 2.9 3 1 0 3 3 3 1 Autophagy-related protein 11 Hydantoinase_A PF01968.13 EMG48339.1 - 0.0016 17.6 0.0 0.008 15.3 0.0 2.1 1 1 0 1 1 1 1 Hydantoinase/oxoprolinase Cgr1 PF03879.9 EMG48339.1 - 0.0023 18.1 12.1 0.0023 18.1 8.4 3.4 3 0 0 3 3 3 1 Cgr1 family YhjQ PF06564.7 EMG48339.1 - 0.016 14.6 2.9 0.69 9.2 0.0 2.4 2 0 0 2 2 2 0 YhjQ protein RNase_PH PF01138.16 EMG48340.1 - 1.6e-14 54.3 0.0 2.6e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EMG48340.1 - 2e-07 30.8 0.0 7.1e-07 29.0 0.0 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 N_Asn_amidohyd PF14736.1 EMG48340.1 - 0.096 11.5 0.1 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase SpoU_methylase PF00588.14 EMG48341.1 - 3.3e-27 95.1 0.0 8.3e-27 93.8 0.0 1.7 1 0 0 1 1 1 1 SpoU rRNA Methylase family Dak1 PF02733.12 EMG48341.1 - 0.16 10.5 0.3 0.7 8.4 0.0 2.0 2 0 0 2 2 2 0 Dak1 domain DUF3445 PF11927.3 EMG48342.1 - 6.9e-82 274.5 0.0 8.4e-82 274.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) PX PF00787.19 EMG48343.1 - 7.4e-18 64.3 0.1 7.4e-18 64.3 0.1 2.8 3 0 0 3 3 3 1 PX domain DUF2893 PF11459.3 EMG48343.1 - 0.039 13.7 0.1 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknwon function (DUF2893) Nup84_Nup100 PF04121.8 EMG48344.1 - 8.6e-180 598.8 19.2 1e-179 598.5 13.3 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 PCI PF01399.22 EMG48345.1 - 7.1e-11 42.3 0.8 7.1e-11 42.3 0.5 3.0 2 1 2 4 4 4 1 PCI domain TPR_11 PF13414.1 EMG48345.1 - 7.3e-06 25.5 2.6 0.0078 15.8 0.0 3.5 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.1 EMG48345.1 - 1.7e-05 25.3 0.0 0.015 15.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.4 EMG48345.1 - 3.5e-05 23.7 5.8 0.0074 16.2 1.5 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMG48345.1 - 0.00066 19.4 3.2 0.29 11.1 0.2 4.4 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMG48345.1 - 0.002 18.4 1.1 0.3 11.4 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMG48345.1 - 0.0097 15.8 3.4 0.5 10.3 0.3 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMG48345.1 - 0.074 13.7 0.0 4.4 8.2 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMG48345.1 - 0.11 13.0 3.0 0.91 10.1 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF627 PF04781.7 EMG48345.1 - 0.15 11.6 3.5 0.17 11.4 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF627) TPR_8 PF13181.1 EMG48345.1 - 0.57 10.0 17.2 1.8 8.5 0.3 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_3 PF07720.7 EMG48345.1 - 0.87 9.4 4.5 0.93 9.3 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SNAP PF14938.1 EMG48345.1 - 1.6 7.7 8.9 3.6 6.6 1.7 3.1 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP Apc3 PF12895.2 EMG48345.1 - 2.2 8.4 8.8 0.12 12.5 0.3 3.0 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Methyltransf_23 PF13489.1 EMG48346.1 - 7e-17 61.6 0.0 1.4e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMG48346.1 - 3.1e-14 53.2 0.0 6.7e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMG48346.1 - 2.5e-13 49.8 0.0 4.6e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMG48346.1 - 2.7e-13 50.2 0.0 4.9e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMG48346.1 - 6.8e-12 45.0 0.0 1.2e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EMG48346.1 - 4.8e-10 40.0 0.0 9.7e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMG48346.1 - 8.2e-09 35.7 0.0 1.8e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EMG48346.1 - 0.00061 19.2 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_26 PF13659.1 EMG48346.1 - 0.00067 19.6 0.0 0.0017 18.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EMG48346.1 - 0.042 12.8 0.0 0.066 12.1 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family MTS PF05175.9 EMG48346.1 - 0.071 12.4 0.0 0.15 11.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain M20_dimer PF07687.9 EMG48347.1 - 9e-09 35.0 0.0 1.5e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain YwhD PF08741.5 EMG48347.1 - 0.021 14.2 0.5 0.051 12.9 0.1 1.7 1 1 1 2 2 2 0 YwhD family Ldh_1_N PF00056.18 EMG48348.1 - 5.5e-45 152.6 0.8 8.9e-45 151.9 0.1 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EMG48348.1 - 2.3e-44 151.1 0.1 3.9e-44 150.4 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain NAD_binding_10 PF13460.1 EMG48348.1 - 0.00039 20.4 0.1 0.00082 19.4 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMG48348.1 - 0.00061 18.5 0.0 0.00091 18.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EMG48348.1 - 0.035 14.3 0.1 0.4 10.9 0.0 2.5 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.11 EMG48348.1 - 0.15 11.4 0.7 1.5 8.1 0.2 2.4 2 1 1 3 3 3 0 Family 4 glycosyl hydrolase Arf PF00025.16 EMG48349.1 - 6.9e-76 253.3 0.3 7.8e-76 253.1 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMG48349.1 - 6.6e-13 48.2 0.0 7.8e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EMG48349.1 - 8.7e-13 47.9 0.1 9.9e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EMG48349.1 - 4.6e-12 45.5 0.0 5.7e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EMG48349.1 - 2.3e-11 43.0 1.2 1e-07 30.9 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EMG48349.1 - 6.8e-11 42.7 0.0 9.2e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EMG48349.1 - 1.9e-05 24.2 0.3 0.00037 19.9 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMG48349.1 - 3.7e-05 23.6 0.0 5.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase ArgK PF03308.11 EMG48349.1 - 0.00068 18.4 1.9 0.034 12.9 0.4 2.8 2 1 0 2 2 2 1 ArgK protein ABC_tran PF00005.22 EMG48349.1 - 0.0044 17.3 0.3 0.01 16.1 0.2 1.7 1 1 0 1 1 1 1 ABC transporter cobW PF02492.14 EMG48349.1 - 0.036 13.5 1.0 3.9 6.8 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 EMG48349.1 - 0.042 13.2 1.3 0.5 9.7 0.1 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NACHT PF05729.7 EMG48349.1 - 0.062 12.9 0.3 5.7 6.5 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 EMG48349.1 - 0.28 11.4 1.7 0.67 10.2 0.3 2.0 1 1 0 2 2 2 0 AAA domain PDH PF02153.12 EMG48350.1 - 5.5e-12 45.1 0.0 8e-12 44.5 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 EMG48350.1 - 2.7e-06 27.3 0.0 5.5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EMG48350.1 - 6.6e-06 25.3 0.0 1.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EMG48350.1 - 1.7e-05 25.1 0.0 4.4e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EMG48350.1 - 0.0029 17.3 0.0 0.0063 16.1 0.0 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EMG48350.1 - 0.0034 16.8 0.0 0.0068 15.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Rossmann-like PF10727.4 EMG48350.1 - 0.016 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain IlvN PF07991.7 EMG48350.1 - 0.021 14.1 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EMG48350.1 - 0.12 12.3 0.2 0.32 11.0 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain GHMP_kinases_N PF00288.21 EMG48351.1 - 3.3e-12 46.2 0.1 6.6e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EMG48351.1 - 3.1e-09 36.9 0.0 1.5e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal Flavi_NS2B PF01002.14 EMG48352.1 - 0.035 13.6 2.4 0.13 11.8 0.0 2.9 3 0 0 3 3 3 0 Flavivirus non-structural protein NS2B EssA PF10661.4 EMG48352.1 - 3.4 7.3 6.0 23 4.6 0.1 3.3 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein EssA TPP_enzyme_M PF00205.17 EMG48353.1 - 3.5e-34 117.4 0.0 6.5e-33 113.3 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 EMG48353.1 - 2.1e-28 98.9 0.0 4.1e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EMG48353.1 - 4.8e-17 61.9 0.7 1.1e-16 60.7 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EMG48353.1 - 0.01 14.5 0.0 0.021 13.5 0.0 1.4 1 0 0 1 1 1 0 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EMG48353.1 - 0.02 13.8 0.0 0.039 12.8 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase PHO4 PF01384.15 EMG48354.1 - 1.1e-113 379.2 16.9 1.3e-113 379.0 11.7 1.1 1 0 0 1 1 1 1 Phosphate transporter family KRAP_IP3R_bind PF14722.1 EMG48354.1 - 0.1 12.1 0.1 0.36 10.3 0.0 1.9 2 0 0 2 2 2 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain Sulfate_transp PF00916.15 EMG48355.1 - 2.6e-52 177.5 7.7 2.6e-52 177.5 5.4 2.1 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EMG48355.1 - 1.2e-21 76.0 6.5 1.2e-21 76.0 4.5 2.3 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EMG48355.1 - 1.8e-18 66.0 0.3 3.5e-18 65.1 0.2 1.5 1 0 0 1 1 1 1 STAS domain Oxidored-like PF09791.4 EMG48356.1 - 4.4e-26 90.0 2.1 9.4e-26 89.0 1.5 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DPM3 PF08285.6 EMG48357.1 - 2.6e-34 116.9 0.1 2.9e-34 116.7 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) QueT PF06177.6 EMG48357.1 - 0.029 14.3 0.1 0.033 14.1 0.1 1.1 1 0 0 1 1 1 0 QueT transporter DUF3180 PF11377.3 EMG48357.1 - 0.097 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) Tau95 PF09734.4 EMG48358.1 - 3.5e-59 200.6 6.0 4.9e-59 200.1 4.1 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit S-antigen PF05756.6 EMG48358.1 - 0.092 12.7 6.9 0.25 11.3 4.8 1.7 1 0 0 1 1 1 0 S-antigen protein BUD22 PF09073.5 EMG48358.1 - 2.2 7.2 13.1 0.22 10.5 4.9 1.9 2 0 0 2 2 2 0 BUD22 NOA36 PF06524.7 EMG48358.1 - 3.5 6.7 11.1 1.6 7.9 6.0 1.6 2 0 0 2 2 2 0 NOA36 protein DUF2457 PF10446.4 EMG48358.1 - 4.1 6.0 19.0 5.8 5.5 13.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CobT PF06213.7 EMG48358.1 - 4.6 6.2 13.6 7 5.6 9.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT M20_dimer PF07687.9 EMG48359.1 - 2.6e-14 52.9 0.0 4.3e-14 52.1 0.0 1.4 1 1 0 1 1 1 1 Peptidase dimerisation domain YwhD PF08741.5 EMG48359.1 - 0.047 13.0 0.5 0.11 11.9 0.1 1.7 1 1 1 2 2 2 0 YwhD family LRR_8 PF13855.1 EMG48360.1 - 9.3e-11 41.3 27.3 5e-06 26.1 0.8 6.6 5 2 2 7 7 7 3 Leucine rich repeat LRR_4 PF12799.2 EMG48360.1 - 5.7e-09 35.3 37.8 0.0044 16.6 0.1 7.8 4 2 4 8 8 8 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMG48360.1 - 0.00014 21.4 27.7 0.2 11.8 0.1 10.1 9 1 0 9 9 9 1 Leucine Rich Repeat F-box PF00646.28 EMG48360.1 - 0.022 14.3 0.3 0.022 14.3 0.2 2.7 3 0 0 3 3 3 0 F-box domain LRR_7 PF13504.1 EMG48360.1 - 0.032 14.3 23.2 2.6 8.6 0.1 10.5 12 0 0 12 12 12 0 Leucine rich repeat F-box-like PF12937.2 EMG48360.1 - 0.035 13.8 2.5 0.072 12.8 0.4 2.7 2 1 0 2 2 2 0 F-box-like FNIP PF05725.7 EMG48360.1 - 0.11 12.4 15.6 9.7 6.2 0.7 6.0 4 2 0 4 4 4 0 FNIP Repeat Carn_acyltransf PF00755.15 EMG48361.1 - 1.5e-192 640.8 0.6 1.7e-192 640.6 0.4 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Glyco_transf_21 PF13506.1 EMG48362.1 - 2.9e-17 62.5 0.0 6e-08 32.1 0.1 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 EMG48362.1 - 9e-12 45.2 0.0 2.1e-11 44.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EMG48362.1 - 0.0003 20.5 0.3 0.00094 18.9 0.1 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 2 RhoGAP PF00620.22 EMG48363.1 - 2.7e-44 150.4 0.2 9.1e-44 148.7 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 EMG48363.1 - 2e-13 50.1 27.2 3.7e-08 33.3 6.0 2.4 2 0 0 2 2 2 2 LIM domain HALZ PF02183.13 EMG48363.1 - 0.00021 20.9 0.7 0.00021 20.9 0.5 3.3 4 0 0 4 4 4 1 Homeobox associated leucine zipper Complex1_LYR PF05347.10 EMG48364.1 - 2.2e-14 52.9 0.2 2.6e-14 52.7 0.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMG48364.1 - 3.6e-12 46.2 0.2 4.2e-12 46.1 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DUF1708 PF08101.6 EMG48364.1 - 0.067 12.0 0.0 0.067 12.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Clathrin_lg_ch PF01086.12 EMG48365.1 - 8.4e-55 186.1 24.2 9.7e-55 185.9 16.8 1.0 1 0 0 1 1 1 1 Clathrin light chain UPF0542 PF15086.1 EMG48365.1 - 0.45 10.2 4.8 0.92 9.2 3.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 CBP4 PF07960.6 EMG48366.1 - 0.16 11.6 6.4 0.024 14.2 1.4 1.9 2 0 0 2 2 2 0 CBP4 Rho_Binding PF08912.6 EMG48366.1 - 0.26 11.6 5.4 0.3 11.3 1.0 2.6 2 0 0 2 2 2 0 Rho Binding Lzipper-MIP1 PF14389.1 EMG48366.1 - 0.3 11.2 7.3 3.5 7.7 0.2 3.0 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 F_actin_cap_B PF01115.12 EMG48367.1 - 1.7e-102 341.7 1.1 2.8e-102 341.0 0.8 1.3 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Pribosyl_synth PF14572.1 EMG48367.1 - 9.2e-31 107.0 0.7 1.4e-30 106.4 0.5 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EMG48367.1 - 3.1e-05 23.7 1.1 6.9e-05 22.5 0.7 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF1293 PF06950.6 EMG48367.1 - 0.09 12.6 0.2 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1293) UPRTase PF14681.1 EMG48367.1 - 0.11 11.7 0.1 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase RFX_DNA_binding PF02257.10 EMG48368.1 - 4.9e-12 45.8 0.7 1.7e-10 40.9 0.5 2.6 1 1 0 1 1 1 1 RFX DNA-binding domain Rubella_E2 PF05749.6 EMG48368.1 - 0.1 11.7 0.4 0.37 10.0 0.2 1.9 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 LRR_8 PF13855.1 EMG48369.1 - 1.5e-18 66.2 25.1 1.3e-06 28.0 0.0 6.3 4 1 2 6 6 6 5 Leucine rich repeat LRR_4 PF12799.2 EMG48369.1 - 3.7e-17 61.5 40.2 6.6e-07 28.8 0.0 9.3 7 2 2 9 9 9 5 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EMG48369.1 - 8.2e-09 34.2 16.7 5.5 7.6 0.0 10.8 11 0 0 11 11 11 3 Leucine rich repeat LRR_6 PF13516.1 EMG48369.1 - 1.8e-08 33.5 18.6 0.24 11.6 0.0 9.6 11 0 0 11 11 11 3 Leucine Rich repeat LRR_1 PF00560.28 EMG48369.1 - 8.1e-06 25.1 38.6 0.54 10.4 0.0 11.2 13 2 0 13 13 13 5 Leucine Rich Repeat FNIP PF05725.7 EMG48369.1 - 0.00043 20.1 29.9 0.022 14.6 0.2 7.4 8 2 0 8 8 8 3 FNIP Repeat F-box PF00646.28 EMG48369.1 - 0.032 13.9 0.0 0.1 12.3 0.0 1.9 1 0 0 1 1 1 0 F-box domain RNase_PH PF01138.16 EMG48371.1 - 1.9e-33 115.6 0.1 2.5e-33 115.2 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EMG48371.1 - 8.9e-06 25.5 0.1 2.4e-05 24.1 0.1 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Mito_carr PF00153.22 EMG48372.1 - 4.5e-58 192.9 1.9 8.6e-20 70.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein His_Phos_2 PF00328.17 EMG48373.1 - 1.6e-40 139.4 0.0 2e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TFIIF_alpha PF05793.7 EMG48374.1 - 5.4e-15 54.7 22.2 3.1e-10 39.0 0.5 3.9 2 1 2 4 4 4 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF383 PF04063.9 EMG48375.1 - 4.6e-73 244.8 2.4 1.5e-72 243.1 0.3 2.5 2 1 1 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EMG48375.1 - 2.1e-24 84.8 0.7 6.2e-24 83.3 0.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Amino_oxidase PF01593.19 EMG48376.1 - 5.1e-54 184.0 0.0 1e-53 183.0 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EMG48376.1 - 9.2e-11 41.6 0.0 1.7e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EMG48376.1 - 1.7e-05 24.0 0.0 2.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMG48376.1 - 8.4e-05 22.7 0.0 0.011 15.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMG48376.1 - 0.0001 22.2 0.6 0.00096 19.0 0.1 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMG48376.1 - 0.00019 20.0 0.2 0.051 12.0 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.19 EMG48376.1 - 0.0006 18.8 0.8 0.0013 17.7 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMG48376.1 - 0.00069 18.5 0.2 0.00098 18.0 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EMG48376.1 - 0.0028 16.6 0.3 0.01 14.7 0.1 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EMG48376.1 - 0.0053 15.8 0.3 0.008 15.2 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EMG48376.1 - 0.0081 16.5 0.5 0.044 14.1 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMG48376.1 - 0.095 12.4 0.3 13 5.4 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 EMG48376.1 - 0.15 11.1 0.2 0.28 10.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Kelch_4 PF13418.1 EMG48377.1 - 2.8e-06 26.9 6.9 3e-05 23.6 0.0 5.5 7 0 0 7 7 7 1 Galactose oxidase, central domain Kelch_1 PF01344.20 EMG48377.1 - 0.38 10.3 4.9 14 5.3 0.0 3.5 3 1 0 3 3 3 0 Kelch motif Kelch_3 PF13415.1 EMG48377.1 - 4.3 7.6 9.7 2.2 8.5 0.0 5.1 5 1 0 5 5 5 0 Galactose oxidase, central domain zf-Tim10_DDP PF02953.10 EMG48378.1 - 1.3e-22 78.8 4.4 1.5e-22 78.6 3.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EMG48378.1 - 0.0081 15.6 3.4 0.01 15.2 2.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Cyto_heme_lyase PF01265.12 EMG48379.1 - 2.5e-88 296.0 6.1 2.9e-88 295.8 4.2 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase SURF4 PF02077.10 EMG48380.1 - 1.2e-89 300.2 12.0 1.4e-89 300.0 8.3 1.0 1 0 0 1 1 1 1 SURF4 family CHU_C PF13585.1 EMG48380.1 - 0.036 13.9 0.1 0.078 12.8 0.1 1.5 1 0 0 1 1 1 0 C-terminal domain of CHU protein family CoA_transf_3 PF02515.12 EMG48381.1 - 1.6e-29 102.4 0.0 3.3e-29 101.4 0.0 1.5 2 0 0 2 2 2 1 CoA-transferase family III HIG_1_N PF04588.8 EMG48381.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Hypoxia induced protein conserved region Fungal_trans PF04082.13 EMG48382.1 - 8.8e-23 80.4 2.2 2.2e-22 79.1 1.6 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG48382.1 - 6.3e-07 29.2 9.5 6.3e-07 29.2 6.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3439 PF11921.3 EMG48382.1 - 4.1 7.1 6.7 1.6 8.4 0.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Sporozoite_P67 PF05642.6 EMG48382.1 - 4.8 4.9 13.7 0.016 13.0 3.2 1.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen PGA2 PF07543.7 EMG48382.1 - 6.8 6.4 6.5 11 5.8 0.1 2.9 3 0 0 3 3 3 0 Protein trafficking PGA2 DUF676 PF05057.9 EMG48383.1 - 7.1e-39 133.3 0.0 1.1e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EMG48383.1 - 1.5e-05 24.6 0.0 3.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EMG48383.1 - 0.0058 16.2 0.0 0.0096 15.5 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DLH PF01738.13 EMG48383.1 - 0.1 11.8 0.0 0.37 10.0 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family ABC1 PF03109.11 EMG48384.1 - 3e-24 85.2 0.2 2.1e-16 59.9 0.1 2.6 2 0 0 2 2 2 2 ABC1 family RIO1 PF01163.17 EMG48384.1 - 0.00062 19.1 0.1 0.0023 17.3 0.0 2.0 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EMG48384.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Fungal_trans PF04082.13 EMG48385.1 - 8.6e-20 70.6 2.1 8.6e-20 70.6 1.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG48385.1 - 7.6e-06 25.7 9.9 1.4e-05 24.9 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF573 PF04504.9 EMG48386.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF573 NUDIX PF00293.23 EMG48387.1 - 6.9e-27 93.7 0.0 1e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Radical_SAM PF04055.16 EMG48388.1 - 2.9e-14 53.5 0.0 5e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Hist_deacetyl PF00850.14 EMG48389.1 - 7.5e-69 232.3 0.1 1.1e-68 231.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain RhoGAP PF00620.22 EMG48390.1 - 8.7e-22 77.3 1.8 3.7e-20 72.0 0.6 2.9 2 1 0 2 2 2 1 RhoGAP domain PX PF00787.19 EMG48390.1 - 2.2e-10 40.3 0.2 2.2e-10 40.3 0.2 2.1 2 0 0 2 2 2 1 PX domain PH PF00169.24 EMG48390.1 - 8.2e-08 32.3 0.1 4e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EMG48390.1 - 0.05 13.8 0.0 0.43 10.8 0.0 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain Nucleoplasmin PF03066.10 EMG48390.1 - 5 6.6 16.6 6.8 6.1 0.2 2.4 2 0 0 2 2 2 0 Nucleoplasmin Glyco_hydro_17 PF00332.13 EMG48392.1 - 1.7e-43 148.8 0.5 1.9e-43 148.6 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Rot1 PF10681.4 EMG48393.1 - 1.4e-47 161.8 0.0 1.6e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Dioxygenase_C PF00775.16 EMG48394.1 - 6.9e-51 172.1 0.0 9e-51 171.7 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EMG48394.1 - 8e-13 48.1 0.0 1.4e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EMG48394.1 - 1.2e-06 28.4 0.0 6.2e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 EMG48394.1 - 0.024 14.6 0.0 0.099 12.6 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4480) DUF4198 PF10670.4 EMG48394.1 - 0.059 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) Glyco_hydro_38 PF01074.17 EMG48395.1 - 2.2e-80 269.8 0.6 5e-80 268.6 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EMG48395.1 - 5.4e-62 210.0 3.0 7.8e-62 209.5 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EMG48395.1 - 3e-23 81.8 0.1 1.1e-22 79.9 0.0 2.1 2 0 0 2 2 2 1 Alpha mannosidase, middle domain ARL6IP6 PF15062.1 EMG48396.1 - 0.024 14.5 0.1 0.055 13.3 0.0 1.6 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix Sod_Cu PF00080.15 EMG48397.1 - 1.2e-28 100.0 0.5 1.4e-28 99.8 0.4 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF4561 PF15120.1 EMG48398.1 - 7.2e-05 22.3 0.3 0.0039 16.6 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4561) LRR_4 PF12799.2 EMG48398.1 - 0.00011 21.7 8.6 0.63 9.7 0.1 5.9 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 EMG48398.1 - 0.004 16.7 0.8 0.014 14.9 0.5 1.9 1 1 0 1 1 1 1 Leucine-rich repeat Methyltrn_RNA_3 PF02598.12 EMG48399.1 - 1.4e-72 244.4 4.3 1.9e-72 244.0 3.0 1.2 1 0 0 1 1 1 1 Putative RNA methyltransferase Pox_A_type_inc PF04508.7 EMG48400.1 - 0.52 10.2 19.3 0.75 9.7 0.1 6.4 4 1 0 4 4 4 0 Viral A-type inclusion protein repeat DASH_Dam1 PF08653.5 EMG48400.1 - 5.5 6.8 7.1 31 4.4 0.1 4.6 5 2 1 6 6 6 0 DASH complex subunit Dam1 Flocculin_t3 PF13928.1 EMG48401.1 - 3.1e-17 62.4 24.7 3.1e-17 62.4 17.1 1.8 2 0 0 2 2 2 1 Flocculin type 3 repeat MoCF_biosynth PF00994.19 EMG48401.1 - 0.064 12.6 0.4 0.072 12.4 0.3 1.2 1 0 0 1 1 1 0 Probable molybdopterin binding domain Flocculin_t3 PF13928.1 EMG48403.1 - 1.4e-27 95.5 46.7 9e-15 54.5 14.4 4.2 3 1 0 3 3 3 2 Flocculin type 3 repeat Herpes_pp85 PF04637.7 EMG48403.1 - 0.63 8.2 4.9 0.84 7.8 3.4 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) NigD PF12667.2 EMG48403.1 - 2.9 7.6 6.7 0.75 9.5 2.2 1.7 1 1 1 2 2 2 0 NigD-like protein IncA PF04156.9 EMG48404.1 - 0.00055 19.5 1.5 0.0012 18.4 1.0 1.5 1 1 0 1 1 1 1 IncA protein DUF3671 PF12420.3 EMG48404.1 - 0.015 15.2 0.2 0.015 15.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function Sigma_reg_N PF13800.1 EMG48404.1 - 0.021 14.8 0.1 0.021 14.8 0.1 2.2 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Fzo_mitofusin PF04799.8 EMG48404.1 - 1.3 8.4 6.8 0.24 10.7 1.9 1.8 2 0 0 2 2 2 0 fzo-like conserved region DUF4404 PF14357.1 EMG48404.1 - 1.3 9.4 10.3 0.051 13.9 1.4 2.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) DUF1664 PF07889.7 EMG48404.1 - 2.2 8.0 6.3 0.72 9.6 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ACCA PF03255.9 EMG48404.1 - 9.2 5.8 8.0 25 4.3 1.6 2.7 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Laminin_II PF06009.7 EMG48404.1 - 10 5.9 12.6 0.16 11.7 0.5 3.2 4 0 0 4 4 4 0 Laminin Domain II Thioredoxin PF00085.15 EMG48405.1 - 1.3e-14 53.6 0.1 4.1e-10 39.2 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EMG48405.1 - 4.9e-06 26.7 0.7 0.00018 21.6 0.4 2.9 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.1 EMG48405.1 - 4.2e-05 23.1 0.1 0.001 18.6 0.1 2.4 2 1 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.1 EMG48405.1 - 0.00014 21.9 7.2 0.012 15.7 2.7 3.8 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EMG48405.1 - 0.038 13.9 0.1 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like LAM_C PF12544.3 EMG48405.1 - 0.21 11.6 2.2 0.17 11.9 0.3 1.8 2 0 0 2 2 2 0 Lysine-2,3-aminomutase Flocculin_t3 PF13928.1 EMG48406.1 - 8.1e-29 99.4 99.2 4.6e-14 52.2 16.0 7.8 8 0 0 8 8 8 4 Flocculin type 3 repeat ATP-gua_PtransN PF02807.10 EMG48406.1 - 0.013 15.6 4.4 0.84 9.8 0.5 3.0 2 0 0 2 2 2 0 ATP:guanido phosphotransferase, N-terminal domain CPSF_A PF03178.10 EMG48407.1 - 3.6e-91 305.5 0.4 1.9e-89 299.9 0.0 2.6 3 0 0 3 3 3 2 CPSF A subunit region PIG-F PF06699.6 EMG48408.1 - 7.1e-61 205.4 9.0 8.7e-61 205.2 6.2 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF2798 PF11391.3 EMG48408.1 - 0.019 14.6 0.9 3.2 7.5 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2798) Redoxin PF08534.5 EMG48409.1 - 2.6e-36 124.3 0.0 2.8e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EMG48409.1 - 5.3e-11 42.2 0.0 6.5e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family zf-Tim10_DDP PF02953.10 EMG48410.1 - 8.4e-21 73.0 0.6 1.1e-20 72.6 0.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3398 PF11878.3 EMG48410.1 - 0.056 13.2 0.1 0.084 12.7 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3398) SR-25 PF10500.4 EMG48410.1 - 0.093 12.1 0.5 0.1 12.0 0.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Proteasome PF00227.21 EMG48411.1 - 1.2e-38 132.2 0.1 8.3e-38 129.5 0.1 1.9 1 1 0 1 1 1 1 Proteasome subunit zf-C2H2 PF00096.21 EMG48412.1 - 7.3e-07 29.1 19.2 0.00036 20.6 1.6 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMG48412.1 - 1.1e-05 25.4 9.5 2.9e-05 24.1 3.2 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMG48412.1 - 0.0059 16.8 18.1 0.036 14.3 0.5 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EMG48412.1 - 0.006 16.7 2.2 1.6 9.0 0.0 3.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type Fungal_trans PF04082.13 EMG48413.1 - 4.7e-19 68.2 1.8 8.5e-19 67.4 0.2 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG48413.1 - 7e-08 32.2 10.8 1.4e-07 31.2 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SR-25 PF10500.4 EMG48413.1 - 0.32 10.4 34.1 0.65 9.4 8.0 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Fungal_trans_2 PF11951.3 EMG48414.1 - 4.2e-27 94.7 2.2 6.9e-27 94.0 1.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG48414.1 - 4.8e-10 39.1 8.3 4.8e-10 39.1 5.8 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RXT2_N PF08595.6 EMG48414.1 - 0.071 12.9 11.0 0.37 10.5 0.4 2.8 2 0 0 2 2 2 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 EMG48414.1 - 0.91 9.0 8.4 1.8 8.0 5.8 1.4 1 0 0 1 1 1 0 Nucleoplasmin BTB_2 PF02214.17 EMG48415.1 - 3.1e-07 30.5 1.4 0.00041 20.4 0.3 2.7 2 0 0 2 2 2 2 BTB/POZ domain Dpoe2NT PF12213.3 EMG48415.1 - 0.063 13.2 0.2 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal MFS_1 PF07690.11 EMG48416.1 - 1.2e-30 106.4 48.3 5.9e-28 97.5 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gemini_C4 PF01492.12 EMG48416.1 - 2.3e-05 24.0 1.7 3.9e-05 23.2 1.2 1.3 1 0 0 1 1 1 1 Geminivirus C4 protein Sugar_tr PF00083.19 EMG48416.1 - 0.0044 15.6 41.1 0.0046 15.5 14.0 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter Sulfate_transp PF00916.15 EMG48418.1 - 6.2e-81 271.4 6.7 1.1e-80 270.6 4.7 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EMG48418.1 - 2.6e-33 113.5 2.1 2.6e-33 113.5 1.4 4.1 5 0 0 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EMG48418.1 - 0.0002 20.7 0.0 0.00045 19.6 0.0 1.6 1 0 0 1 1 1 1 STAS domain FGGY_C PF02782.11 EMG48419.1 - 5.8e-54 182.7 0.1 9.3e-54 182.0 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EMG48419.1 - 7.6e-22 77.8 0.0 4.9e-21 75.1 0.0 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.16 EMG48419.1 - 0.025 13.8 0.0 0.074 12.3 0.0 1.7 2 0 0 2 2 2 0 Hexokinase BcrAD_BadFG PF01869.15 EMG48419.1 - 0.048 12.9 0.0 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family NblA PF04485.7 EMG48419.1 - 0.13 12.1 0.4 0.27 11.1 0.3 1.5 1 0 0 1 1 1 0 Phycobilisome degradation protein nblA CBFD_NFYB_HMF PF00808.18 EMG48420.1 - 3.7e-13 49.3 1.0 7e-13 48.4 0.7 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMG48420.1 - 5.4e-06 26.4 0.2 9.7e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF4452 PF14618.1 EMG48420.1 - 0.075 12.8 1.2 0.11 12.3 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) RNA_pol_Rpo13 PF12136.3 EMG48420.1 - 0.081 12.6 2.4 0.67 9.6 0.6 2.7 3 0 0 3 3 3 0 RNA polymerase Rpo13 subunit HTH domain tRNA_int_endo PF01974.12 EMG48421.1 - 1.3e-28 98.6 0.4 2.6e-28 97.6 0.3 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EMG48421.1 - 0.02 14.4 0.0 1.4 8.5 0.0 2.6 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain adh_short PF00106.20 EMG48422.1 - 2.4e-15 56.8 0.0 3.5e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMG48422.1 - 1.1e-08 34.9 0.0 1.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EMG48422.1 - 0.0046 15.9 0.0 0.0074 15.2 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EMG48422.1 - 0.0089 14.9 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EMG48422.1 - 0.11 12.4 0.1 1.3 9.0 0.1 2.2 1 1 0 1 1 1 0 NADH(P)-binding APG6 PF04111.7 EMG48423.1 - 1.5e-90 303.4 14.6 1.5e-90 303.4 10.1 1.8 2 0 0 2 2 2 1 Autophagy protein Apg6 G6PD_C PF02781.11 EMG48423.1 - 0.015 14.1 1.8 1.7 7.3 0.2 2.2 2 0 0 2 2 2 0 Glucose-6-phosphate dehydrogenase, C-terminal domain Zn_clus PF00172.13 EMG48424.1 - 4.7e-07 29.6 6.9 4.7e-07 29.6 4.8 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EMP70 PF02990.11 EMG48425.1 - 3e-195 649.6 14.4 4.1e-195 649.1 10.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Zn_clus PF00172.13 EMG48426.1 - 2.9e-07 30.2 11.9 4.5e-07 29.6 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF221 PF02714.10 EMG48427.1 - 9.7e-75 251.4 16.3 9.7e-75 251.4 11.3 1.4 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EMG48427.1 - 1.6e-07 31.0 2.6 2.6e-07 30.3 0.1 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport Rad4 PF03835.10 EMG48429.1 - 4.6e-29 100.7 0.1 1.5e-28 99.0 0.0 1.9 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EMG48429.1 - 8.2e-25 86.3 0.0 1.7e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EMG48429.1 - 1.5e-15 56.4 1.2 3.5e-15 55.2 0.1 2.3 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EMG48429.1 - 2.1e-14 53.5 0.1 2.1e-14 53.5 0.1 3.9 4 0 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EMG48429.1 - 0.13 12.4 0.0 0.44 10.7 0.0 1.9 1 1 0 1 1 1 0 Transglutaminase-like superfamily RNase_H2_suC PF08615.6 EMG48430.1 - 1.2e-22 80.2 0.0 1.5e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) AAA_11 PF13086.1 EMG48430.1 - 0.066 12.7 0.1 0.077 12.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 EMG48431.1 - 8.1e-44 149.7 55.3 1.7e-43 148.7 37.2 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG48431.1 - 5.8e-12 44.9 15.9 5.8e-12 44.9 11.0 2.6 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EMG48431.1 - 2.4e-10 39.2 15.2 4.4e-08 31.7 8.5 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF997 PF06196.7 EMG48431.1 - 7.6 6.1 11.3 7.4 6.1 0.5 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF997) EamA PF00892.15 EMG48432.1 - 1.3e-10 41.4 0.5 1.3e-10 41.4 0.3 3.4 3 1 1 4 4 4 1 EamA-like transporter family TPT PF03151.11 EMG48432.1 - 6.5e-07 29.1 24.4 0.00095 18.8 3.0 2.6 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 EMG48432.1 - 1.8e-05 24.8 20.9 0.00017 21.7 0.1 3.4 5 0 0 5 5 5 2 Multidrug resistance efflux transporter UAA PF08449.6 EMG48432.1 - 2.1e-05 23.6 16.8 3.8e-05 22.7 11.7 1.5 1 1 0 1 1 1 1 UAA transporter family DIOX_N PF14226.1 EMG48433.1 - 1.6e-17 64.1 0.0 2.8e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMG48433.1 - 1.7e-14 53.8 0.0 5.3e-14 52.3 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Kelch_6 PF13964.1 EMG48433.1 - 0.12 12.5 0.1 0.38 10.9 0.0 1.8 2 0 0 2 2 2 0 Kelch motif Met_10 PF02475.11 EMG48434.1 - 3.6e-70 235.6 0.0 5.9e-70 234.9 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.10 EMG48434.1 - 0.0094 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase TRM PF02005.11 EMG48434.1 - 0.01 14.7 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_18 PF12847.2 EMG48434.1 - 0.056 14.0 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ECR1_N PF14382.1 EMG48435.1 - 1.5e-12 46.6 0.0 5.2e-12 44.8 0.0 2.0 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EMG48435.1 - 0.0077 16.1 0.0 0.16 11.9 0.0 2.4 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 RF-1 PF00472.15 EMG48436.1 - 7.1e-35 119.2 3.7 1.2e-34 118.5 2.6 1.4 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EMG48436.1 - 5.8e-27 93.7 0.2 6.1e-26 90.3 0.0 2.4 2 0 0 2 2 2 1 PCRF domain Oxysterol_BP PF01237.13 EMG48438.1 - 5.7e-108 360.5 0.8 5.7e-108 360.5 0.5 1.5 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 EMG48438.1 - 1.4e-37 127.5 0.4 3.1e-37 126.5 0.3 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EMG48438.1 - 3.8e-06 27.0 0.5 0.00012 22.1 0.1 2.8 2 0 0 2 2 2 1 PH domain PH_3 PF14593.1 EMG48438.1 - 0.00016 21.4 0.1 0.00036 20.3 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMG48438.1 - 0.9 9.8 7.8 0.52 10.5 0.4 3.6 3 1 1 4 4 4 0 Pleckstrin homology domain Troponin-I_N PF11636.3 EMG48438.1 - 1 9.1 6.8 4.4 7.0 4.7 2.1 1 0 0 1 1 1 0 Troponin I residues 1-32 zf-C3HC4_2 PF13923.1 EMG48439.1 - 7e-08 32.3 5.2 7e-08 32.3 3.6 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMG48439.1 - 3.7e-07 29.8 4.6 3.7e-07 29.8 3.2 2.9 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EMG48439.1 - 4.7e-06 26.1 7.3 4.7e-06 26.1 5.0 3.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMG48439.1 - 1.8e-05 24.3 2.0 1.8e-05 24.3 1.4 2.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EMG48439.1 - 7.6e-05 22.3 3.1 7.6e-05 22.3 2.2 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMG48439.1 - 8.5e-05 22.3 5.8 8.5e-05 22.3 4.0 2.5 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EMG48439.1 - 0.00013 21.6 5.5 0.00013 21.6 3.8 3.1 2 1 0 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.3 EMG48439.1 - 0.00092 18.6 2.2 0.00092 18.6 1.5 2.3 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Cript PF10235.4 EMG48439.1 - 0.16 12.3 16.0 0.045 14.0 4.4 2.7 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT G_glu_transpept PF01019.16 EMG48440.1 - 6.2e-127 424.1 0.0 7e-127 423.9 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase ABC2_membrane PF01061.19 EMG48441.1 - 2.5e-83 278.3 62.3 5e-43 146.7 17.7 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EMG48441.1 - 8.3e-42 142.7 0.0 1e-19 71.2 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 EMG48441.1 - 2.3e-31 107.5 0.8 1.6e-27 95.1 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EMG48441.1 - 1.2e-22 79.7 0.0 3.2e-22 78.4 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EMG48441.1 - 2.4e-09 36.8 0.0 0.00019 20.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EMG48441.1 - 3.7e-07 29.4 0.1 4.1e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EMG48441.1 - 6.4e-06 25.6 0.3 0.0013 18.2 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EMG48441.1 - 3.5e-05 23.8 1.0 6.9e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 EMG48441.1 - 0.00015 21.7 0.1 0.049 13.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EMG48441.1 - 0.00016 22.4 0.3 0.0052 17.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain SMC_N PF02463.14 EMG48441.1 - 0.00035 19.8 0.1 0.072 12.3 0.0 2.9 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.2 EMG48441.1 - 0.00039 19.5 49.1 0.019 13.9 13.5 3.1 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EMG48441.1 - 0.0006 19.8 2.4 0.04 13.8 0.0 3.6 4 0 0 4 4 2 1 AAA domain UPF0079 PF02367.12 EMG48441.1 - 0.00065 19.3 0.6 0.038 13.6 0.1 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 EMG48441.1 - 0.001 18.5 2.0 0.043 13.2 0.4 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 EMG48441.1 - 0.0013 18.4 0.2 0.54 10.0 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 EMG48441.1 - 0.0025 17.8 1.5 0.0036 17.2 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMG48441.1 - 0.0028 17.9 0.7 0.023 15.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EMG48441.1 - 0.003 17.4 0.1 0.064 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EMG48441.1 - 0.0039 17.5 0.1 0.11 12.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EMG48441.1 - 0.0049 16.4 0.1 0.3 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EMG48441.1 - 0.0089 15.5 0.0 4.8 6.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.1 EMG48441.1 - 0.013 15.6 0.6 0.25 11.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain NACHT PF05729.7 EMG48441.1 - 0.014 15.0 0.8 0.36 10.4 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_10 PF12846.2 EMG48441.1 - 0.017 14.5 0.4 4 6.7 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain Miro PF08477.8 EMG48441.1 - 0.099 13.1 0.1 19 5.7 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein Thymidylate_kin PF02223.12 EMG48441.1 - 0.14 11.4 0.1 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase ATP_bind_1 PF03029.12 EMG48441.1 - 0.27 10.7 1.8 4.3 6.8 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 EMG48441.1 - 0.33 9.6 0.7 6.9 5.3 0.1 2.2 2 0 0 2 2 2 0 ArgK protein NTPase_1 PF03266.10 EMG48441.1 - 0.44 10.2 3.6 2.4 7.8 0.4 2.9 3 0 0 3 3 3 0 NTPase Dynamin_N PF00350.18 EMG48441.1 - 0.45 10.3 1.7 0.88 9.3 0.0 2.4 3 0 0 3 3 2 0 Dynamin family ABC_ATPase PF09818.4 EMG48441.1 - 0.51 8.8 0.7 0.92 8.0 0.1 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Glyco_hydro_16 PF00722.16 EMG48442.1 - 0.063 12.5 2.8 0.079 12.2 1.9 1.3 1 1 0 1 1 1 0 Glycosyl hydrolases family 16 DUF1517 PF07466.6 EMG48442.1 - 2.7 6.9 8.9 3 6.7 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Period_C PF12114.3 EMG48442.1 - 6.4 6.3 9.1 8.6 5.9 6.3 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF2348 PF09807.4 EMG48444.1 - 0.00015 21.0 0.0 0.014 14.5 0.0 2.3 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2348) DUF3336 PF11815.3 EMG48445.1 - 4.5e-37 126.7 3.5 9.2e-37 125.7 2.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EMG48445.1 - 5.4e-07 29.7 0.0 1.8e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase PP2C_2 PF13672.1 EMG48446.1 - 4.2e-12 45.9 0.0 6.1e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EMG48446.1 - 5.5e-09 35.9 0.0 1.1e-08 35.0 0.0 1.5 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EMG48446.1 - 4e-07 29.6 0.3 0.0039 16.6 0.0 2.2 1 1 1 2 2 2 2 Protein phosphatase 2C AAA_5 PF07728.9 EMG48447.1 - 5.4e-131 431.1 0.8 1.1e-26 93.2 0.0 8.7 8 0 0 8 8 8 8 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EMG48447.1 - 5.6e-33 113.3 0.0 1.4e-08 34.3 0.0 7.0 7 0 0 7 7 7 6 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EMG48447.1 - 7.5e-31 107.0 0.1 0.00011 22.3 0.0 7.3 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EMG48447.1 - 1.4e-21 76.7 5.7 0.00086 19.2 0.0 9.3 8 1 1 9 9 8 4 AAA domain AAA_22 PF13401.1 EMG48447.1 - 3.2e-21 75.8 7.7 0.0013 18.8 0.0 8.6 9 1 0 9 9 6 5 AAA domain Sigma54_activat PF00158.21 EMG48447.1 - 1.8e-20 73.0 0.1 0.00054 19.4 0.0 6.3 6 0 0 6 6 6 5 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EMG48447.1 - 6.1e-20 71.6 3.7 0.0067 16.4 0.0 7.7 8 0 0 8 8 7 4 Sigma-54 interaction domain AAA_16 PF13191.1 EMG48447.1 - 2.1e-18 66.9 0.4 0.0022 18.0 0.0 8.2 7 0 0 7 7 6 4 AAA ATPase domain AAA_33 PF13671.1 EMG48447.1 - 5.2e-17 62.0 0.1 0.006 16.4 0.0 6.9 6 1 0 6 6 6 4 AAA domain T2SE PF00437.15 EMG48447.1 - 1.7e-16 59.9 4.2 0.0079 15.1 0.0 6.6 6 0 0 6 6 6 4 Type II/IV secretion system protein AAA_30 PF13604.1 EMG48447.1 - 5.4e-14 52.2 2.7 0.17 11.4 0.1 7.5 8 0 0 8 8 7 3 AAA domain UPF0079 PF02367.12 EMG48447.1 - 5.9e-14 51.7 3.7 0.064 12.8 0.0 6.8 6 0 0 6 6 6 4 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EMG48447.1 - 1.3e-13 51.0 5.7 0.51 10.5 0.0 8.5 8 0 0 8 8 7 2 RNA helicase ABC_tran PF00005.22 EMG48447.1 - 3.6e-13 49.9 15.8 0.00079 19.7 0.0 7.5 7 0 0 7 7 6 3 ABC transporter Zeta_toxin PF06414.7 EMG48447.1 - 1.1e-12 47.5 1.4 0.26 10.3 0.0 6.3 6 0 0 6 6 6 4 Zeta toxin AAA_17 PF13207.1 EMG48447.1 - 1.7e-12 48.2 36.1 0.015 16.0 0.0 9.4 8 1 0 8 8 6 6 AAA domain AAA_19 PF13245.1 EMG48447.1 - 3.5e-12 45.8 7.9 0.13 12.0 0.0 6.5 6 0 0 6 6 6 3 Part of AAA domain Mg_chelatase PF01078.16 EMG48447.1 - 1.8e-10 40.3 0.1 0.38 9.8 0.0 7.7 8 0 0 8 8 8 1 Magnesium chelatase, subunit ChlI Miro PF08477.8 EMG48447.1 - 2.5e-10 40.8 3.9 0.15 12.5 0.1 7.0 6 0 0 6 6 6 1 Miro-like protein MobB PF03205.9 EMG48447.1 - 5.2e-10 39.1 5.7 0.19 11.4 0.1 6.6 6 0 0 6 6 6 2 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EMG48447.1 - 1.1e-09 37.6 5.3 0.54 9.4 0.2 6.5 7 0 0 7 7 7 3 Protein of unknown function, DUF258 NACHT PF05729.7 EMG48447.1 - 1.2e-09 38.0 6.2 0.49 10.0 0.1 6.2 6 0 0 6 6 5 4 NACHT domain PduV-EutP PF10662.4 EMG48447.1 - 2.4e-08 33.5 4.2 0.12 11.8 0.0 6.0 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation RuvB_N PF05496.7 EMG48447.1 - 2.4e-08 33.3 4.3 0.055 12.5 0.0 6.2 7 0 0 7 7 7 3 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 EMG48447.1 - 4.5e-08 32.5 0.1 1.1 8.8 0.0 6.2 6 0 0 6 6 6 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EMG48447.1 - 7.3e-08 32.0 1.7 1.3 8.3 0.0 5.5 5 0 0 5 5 5 2 AAA domain AAA_28 PF13521.1 EMG48447.1 - 1.8e-07 31.2 9.7 0.86 9.5 0.0 7.2 7 0 0 7 7 7 1 AAA domain IstB_IS21 PF01695.12 EMG48447.1 - 1.8e-07 30.7 0.1 0.092 12.1 0.0 6.2 7 0 0 7 7 6 1 IstB-like ATP binding protein AAA_7 PF12775.2 EMG48447.1 - 2e-07 30.3 1.8 0.022 13.8 0.0 4.2 4 0 0 4 4 4 2 P-loop containing dynein motor region D3 Viral_helicase1 PF01443.13 EMG48447.1 - 3.2e-06 26.8 0.3 0.66 9.4 0.0 5.2 5 0 0 5 5 5 1 Viral (Superfamily 1) RNA helicase SRP54 PF00448.17 EMG48447.1 - 1.4e-05 24.6 8.5 0.4 10.0 0.2 5.6 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain ATP-synt_ab PF00006.20 EMG48447.1 - 2.6e-05 23.8 0.0 3.3 7.1 0.0 4.0 3 1 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 EMG48447.1 - 0.00013 21.7 10.6 2.1 8.0 0.6 6.0 6 0 0 6 6 5 1 NTPase AAA_18 PF13238.1 EMG48447.1 - 0.022 15.0 0.0 0.12 12.6 0.0 10.6 9 2 0 9 9 6 0 AAA domain FtsK_SpoIIIE PF01580.13 EMG48447.1 - 0.089 12.2 1.6 20 4.5 0.0 4.5 5 0 0 5 5 4 0 FtsK/SpoIIIE family Retrotrans_gag PF03732.12 EMG48449.1 - 0.00058 19.8 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein PolyA_pol PF01743.15 EMG48451.1 - 1.5e-11 44.6 0.0 4.6e-11 43.0 0.0 1.9 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EMG48451.1 - 5.1e-11 41.9 0.3 1.4e-10 40.5 0.1 2.0 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EMG48451.1 - 0.00035 20.3 0.0 0.00075 19.3 0.0 1.5 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative EPSP_synthase PF00275.15 EMG48452.1 - 3.6e-131 437.4 0.0 5.3e-131 436.8 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EMG48452.1 - 5.5e-100 333.5 0.0 9e-100 332.8 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EMG48452.1 - 1.8e-54 184.7 0.0 3.4e-54 183.8 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EMG48452.1 - 2.6e-34 118.3 0.1 1.8e-33 115.6 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EMG48452.1 - 4.4e-22 77.9 0.0 1.3e-21 76.4 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EMG48452.1 - 2.9e-15 56.5 0.0 9.7e-15 54.8 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EMG48452.1 - 7.5e-09 35.2 0.0 1.9e-08 33.9 0.0 1.7 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EMG48452.1 - 2.7e-07 31.4 0.0 1.1e-06 29.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain Fe-ADH PF00465.14 EMG48452.1 - 0.00077 18.2 1.3 0.0028 16.3 0.9 1.9 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_18 PF13238.1 EMG48452.1 - 0.0014 18.9 0.1 0.0037 17.5 0.1 1.8 1 0 0 1 1 1 1 AAA domain YqgF PF14639.1 EMG48452.1 - 0.011 15.3 0.1 0.03 13.8 0.1 1.7 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 AAA_33 PF13671.1 EMG48452.1 - 0.013 15.3 0.0 0.038 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EMG48452.1 - 0.032 14.1 0.0 0.1 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EMG48452.1 - 0.076 13.1 0.1 0.45 10.6 0.0 2.3 1 0 0 1 1 1 0 AAA domain MDFI PF15316.1 EMG48453.1 - 0.75 9.7 15.3 1.1 9.2 10.6 1.2 1 0 0 1 1 1 0 MyoD family inhibitor Peptidase_M22 PF00814.20 EMG48454.1 - 1.8e-51 175.1 0.0 2.6e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 Glycoprotease family YycC PF14174.1 EMG48454.1 - 0.088 12.4 0.1 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 YycC-like protein Nse4_C PF08743.5 EMG48455.1 - 2.1e-21 75.7 0.6 7.3e-21 73.9 0.0 2.2 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EMG48455.1 - 0.00085 19.1 5.0 0.003 17.3 3.5 2.0 1 1 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DNA_mis_repair PF01119.14 EMG48456.1 - 3.3e-34 116.8 0.6 6.2e-34 115.9 0.1 1.8 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EMG48456.1 - 4.6e-12 45.7 0.0 1.1e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EMG48456.1 - 6.2e-08 32.3 0.0 1.3e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_14 PF13428.1 EMG48457.1 - 0.0017 18.7 0.0 2.1 9.2 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMG48457.1 - 0.0045 17.6 0.1 4.7 8.0 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.1 EMG48457.1 - 0.012 14.6 2.2 0.045 12.8 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMG48457.1 - 0.069 12.9 11.1 0.51 10.2 0.6 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EMG48457.1 - 0.085 12.5 6.3 20 4.9 0.0 5.1 5 0 0 5 5 5 0 TPR repeat TPR_17 PF13431.1 EMG48457.1 - 0.69 10.2 9.9 20 5.7 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMG48457.1 - 1.8 8.3 10.5 0.42 10.3 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Zn_clus PF00172.13 EMG48458.1 - 2.6e-08 33.6 5.1 4.7e-08 32.8 3.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUI1 PF01253.17 EMG48459.1 - 4.2e-20 71.3 3.9 7.9e-20 70.4 2.7 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cgr1 PF03879.9 EMG48459.1 - 0.00069 19.7 8.9 0.00069 19.7 6.2 1.9 2 0 0 2 2 2 1 Cgr1 family PH_BEACH PF14844.1 EMG48459.1 - 0.061 13.1 0.6 0.11 12.3 0.4 1.4 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH Suc_Fer-like PF06999.7 EMG48459.1 - 0.29 11.1 3.5 0.44 10.5 2.4 1.5 1 1 0 1 1 1 0 Sucrase/ferredoxin-like PIN_2 PF10130.4 EMG48459.1 - 1.2 9.1 4.9 0.32 11.0 0.3 2.1 1 1 1 2 2 2 0 PIN domain adh_short_C2 PF13561.1 EMG48461.1 - 4.4e-27 95.4 0.0 5.5e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMG48461.1 - 2.5e-24 86.0 2.0 3.2e-24 85.7 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMG48461.1 - 2.1e-10 40.5 0.5 3.1e-10 40.0 0.3 1.2 1 0 0 1 1 1 1 KR domain PDZ PF00595.19 EMG48461.1 - 0.098 12.8 0.2 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Mito_carr PF00153.22 EMG48462.1 - 2.3e-62 206.7 1.9 9.7e-22 76.5 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L24e PF01246.15 EMG48463.1 - 8.2e-26 89.6 1.3 8.2e-26 89.6 0.9 2.0 3 0 0 3 3 3 1 Ribosomal protein L24e Daxx PF03344.10 EMG48463.1 - 0.77 8.1 16.8 0.99 7.8 11.7 1.1 1 0 0 1 1 1 0 Daxx Family DltD_M PF04918.7 EMG48463.1 - 0.94 9.6 5.5 1.6 8.9 3.8 1.4 1 0 0 1 1 1 0 DltD central region TRAP_alpha PF03896.11 EMG48463.1 - 5.6 5.8 10.4 8.4 5.2 7.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit HECT PF00632.20 EMG48464.1 - 7.2e-87 291.4 2.5 7.2e-87 291.4 1.8 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 EMG48464.1 - 0.029 14.0 0.0 0.07 12.8 0.0 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif Hydrolase_6 PF13344.1 EMG48465.1 - 2.1e-26 91.7 0.0 3.8e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMG48465.1 - 1.2e-09 37.7 0.0 2.9e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EMG48465.1 - 2.3e-08 34.7 0.0 2.7e-07 31.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMG48465.1 - 3.4e-05 24.1 0.0 0.089 13.0 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Arch_ATPase PF01637.13 EMG48466.1 - 6.4e-06 26.0 2.1 8.9e-06 25.5 0.3 2.0 2 0 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 EMG48466.1 - 6.8e-05 22.9 0.3 0.015 15.3 0.2 3.2 2 1 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 EMG48466.1 - 0.019 15.4 0.1 0.11 13.0 0.0 2.3 1 1 0 1 1 1 0 Miro-like protein AAA_5 PF07728.9 EMG48466.1 - 0.028 14.1 0.5 0.75 9.5 0.1 3.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EMG48466.1 - 0.037 14.2 0.1 0.1 12.8 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMG48466.1 - 0.037 14.1 0.4 0.15 12.2 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EMG48466.1 - 0.13 11.6 0.0 0.32 10.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 EMG48467.1 - 1e-10 40.8 37.3 1e-10 40.8 25.9 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMG48467.1 - 1.5e-06 26.6 22.9 2.1e-06 26.2 15.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UPF0542 PF15086.1 EMG48467.1 - 0.14 11.8 0.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Enoyl_reductase PF12241.3 EMG48467.1 - 0.15 11.0 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region Rpp20 PF12328.3 EMG48468.1 - 5.6e-30 103.8 2.4 7.1e-30 103.5 1.7 1.1 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EMG48468.1 - 2.7e-13 49.2 1.8 4.2e-13 48.6 1.3 1.3 1 0 0 1 1 1 1 Alba WASH-7_mid PF14744.1 EMG48468.1 - 0.0039 16.0 0.4 0.0046 15.8 0.2 1.1 1 0 0 1 1 1 1 WASH complex subunit 7 DUF3779 PF12621.3 EMG48468.1 - 0.0074 16.1 0.4 0.017 15.0 0.1 1.8 1 1 1 2 2 2 1 Phosphate metabolism protein KCl_Cotrans_1 PF03522.10 EMG48469.1 - 2.5 7.6 6.4 2.6 7.6 1.8 2.5 3 0 0 3 3 3 0 K-Cl Co-transporter type 1 (KCC1) Pam16 PF03656.8 EMG48471.1 - 2.6e-07 30.4 0.1 3.2e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.26 EMG48471.1 - 2.6e-06 27.0 0.0 4.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Histone PF00125.19 EMG48472.1 - 2.3e-32 110.9 0.3 2.8e-32 110.6 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EMG48472.1 - 1e-06 28.7 0.0 1.4e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EMG48472.1 - 0.0045 17.0 0.1 0.0066 16.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Y_phosphatase2 PF03162.8 EMG48473.1 - 6.4e-57 191.5 0.2 1e-56 190.8 0.1 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EMG48473.1 - 2e-07 31.4 0.0 4.1e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EMG48473.1 - 6.7e-05 22.4 0.0 0.00015 21.3 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMG48473.1 - 0.0023 17.2 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Protocadherin PF08374.6 EMG48473.1 - 0.056 13.0 0.7 0.095 12.3 0.5 1.3 1 0 0 1 1 1 0 Protocadherin Aminotran_1_2 PF00155.16 EMG48474.1 - 5.2e-77 259.2 0.0 5.8e-77 259.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_transf_15 PF01793.11 EMG48475.1 - 1e-123 412.5 11.7 1e-123 412.5 8.1 2.1 2 0 0 2 2 2 1 Glycolipid 2-alpha-mannosyltransferase Sds3 PF08598.6 EMG48475.1 - 1.4e-47 161.8 4.3 2.3e-47 161.1 2.9 1.4 1 0 0 1 1 1 1 Sds3-like Acetyltransf_1 PF00583.19 EMG48476.1 - 2.6e-05 24.1 0.1 9.4e-05 22.3 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EMG48476.1 - 0.0029 17.5 0.0 0.0052 16.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMG48476.1 - 0.036 14.2 0.1 0.089 12.9 0.1 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMG48476.1 - 0.043 13.9 0.0 0.095 12.8 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain AAA_12 PF13087.1 EMG48478.1 - 1.4e-57 194.2 0.0 3.3e-57 193.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EMG48478.1 - 2.9e-42 144.8 0.2 2.9e-42 144.8 0.1 2.5 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EMG48478.1 - 4.6e-12 45.5 0.0 1e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EMG48478.1 - 2.1e-11 43.7 0.0 1.3e-10 41.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EMG48478.1 - 3.4e-05 23.4 0.0 0.032 13.7 0.0 3.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EMG48478.1 - 0.00064 19.5 0.0 0.00064 19.5 0.0 2.6 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EMG48478.1 - 0.00077 18.9 0.3 0.016 14.6 0.2 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.11 EMG48478.1 - 0.00086 18.5 0.0 0.017 14.3 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein Arch_ATPase PF01637.13 EMG48478.1 - 0.0022 17.7 0.5 0.0068 16.1 0.0 2.0 2 0 0 2 2 2 1 Archaeal ATPase UPF1_Zn_bind PF09416.5 EMG48478.1 - 0.0023 17.5 1.1 0.0061 16.1 0.8 1.6 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) zf-C2H2_jaz PF12171.3 EMG48478.1 - 0.0033 17.5 0.5 0.01 15.9 0.4 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA PF00004.24 EMG48478.1 - 0.004 17.3 0.0 0.015 15.4 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) zf-C2H2_2 PF12756.2 EMG48478.1 - 0.0059 16.6 2.9 0.0071 16.4 0.9 2.0 2 0 0 2 2 1 1 C2H2 type zinc-finger (2 copies) AAA_22 PF13401.1 EMG48478.1 - 0.02 15.0 0.0 0.13 12.4 0.0 2.3 1 1 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.1 EMG48478.1 - 0.022 14.9 0.0 0.06 13.4 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_14 PF13173.1 EMG48478.1 - 0.027 14.3 0.0 0.15 11.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EMG48478.1 - 0.045 14.0 0.2 4.2 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EMG48478.1 - 0.084 12.2 0.0 0.32 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EMG48478.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ThiF PF00899.16 EMG48479.1 - 7.3e-29 100.3 0.0 1.7e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EMG48479.1 - 0.00019 21.5 0.0 0.0012 18.9 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EMG48479.1 - 0.0016 17.6 0.0 0.1 11.7 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Spc97_Spc98 PF04130.8 EMG48480.1 - 8.9e-82 275.1 21.2 1.2e-81 274.7 14.1 1.6 1 1 0 1 1 1 1 Spc97 / Spc98 family Proteasome PF00227.21 EMG48481.1 - 5.6e-55 185.5 0.1 7.4e-55 185.1 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMG48481.1 - 1.9e-13 49.4 0.1 3.8e-13 48.4 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ATP-grasp_2 PF08442.5 EMG48482.1 - 4.9e-72 241.5 0.0 7.3e-72 240.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EMG48482.1 - 3.3e-24 85.2 0.8 7.2e-24 84.1 0.1 2.0 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 EMG48482.1 - 5.9e-11 42.0 0.2 1.5e-10 40.7 0.1 1.7 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 EMG48482.1 - 8.9e-05 22.1 0.1 0.0016 18.0 0.0 2.2 1 1 1 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 EMG48482.1 - 0.00086 19.0 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Phage_sheath_1 PF04984.9 EMG48482.1 - 0.06 11.7 0.1 0.085 11.2 0.1 1.2 1 0 0 1 1 1 0 Phage tail sheath protein CIAPIN1 PF05093.8 EMG48483.1 - 2.4e-34 117.4 3.7 2.4e-34 117.4 2.6 1.9 2 0 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis MFS_1 PF07690.11 EMG48484.1 - 1.9e-20 72.8 18.5 1.9e-20 72.8 12.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3778 PF12620.3 EMG48485.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3778) NAD_binding_6 PF08030.7 EMG48486.1 - 2.1e-22 79.7 0.3 4.6e-22 78.5 0.1 1.6 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMG48486.1 - 7.4e-22 77.2 0.0 1.6e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EMG48486.1 - 5.5e-18 65.2 15.2 5.5e-18 65.2 10.5 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EMG48486.1 - 0.0092 16.5 0.0 0.034 14.6 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NMD3 PF04981.8 EMG48487.1 - 1.2e-76 257.0 2.1 1.2e-76 257.0 1.4 1.6 2 0 0 2 2 2 1 NMD3 family VPS11_C PF12451.3 EMG48487.1 - 0.0051 16.6 1.8 0.011 15.6 1.3 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal HypA PF01155.14 EMG48487.1 - 1.4 8.5 4.7 10 5.8 0.0 2.6 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family FYVE PF01363.16 EMG48487.1 - 1.9 8.4 6.5 3.3 7.6 2.3 2.4 2 0 0 2 2 2 0 FYVE zinc finger zinc_ribbon_6 PF14599.1 EMG48487.1 - 5.5 6.8 9.1 0.32 10.8 0.1 3.3 2 1 1 3 3 3 0 Zinc-ribbon Bromodomain PF00439.20 EMG48488.1 - 4.6e-26 90.5 1.3 1e-25 89.4 0.9 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EMG48488.1 - 4.4e-09 36.3 0.2 8.9e-09 35.3 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMG48488.1 - 1.3e-08 34.7 0.0 2.4e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMG48488.1 - 0.0064 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1492 PF07374.6 EMG48488.1 - 0.04 14.0 0.2 0.086 12.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) CENP-T PF15511.1 EMG48488.1 - 0.32 10.1 11.8 0.48 9.6 8.2 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CDC45 PF02724.9 EMG48488.1 - 4.4 5.2 20.8 8.2 4.3 14.4 1.4 1 0 0 1 1 1 0 CDC45-like protein Glucosamine_iso PF01182.15 EMG48489.1 - 1.1e-55 188.4 0.0 1.3e-55 188.2 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase CPDase PF07823.6 EMG48490.1 - 4.3e-71 238.4 0.2 5.5e-71 238.1 0.2 1.1 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 EMG48490.1 - 1.3e-06 28.2 0.1 0.00012 21.8 0.1 2.4 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 EMG48490.1 - 0.1 12.5 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 LigT like Phosphoesterase DUF3227 PF11537.3 EMG48490.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3227) Adaptin_N PF01602.15 EMG48491.1 - 2e-115 386.1 11.0 2.4e-115 385.8 7.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EMG48491.1 - 5.1e-20 71.9 0.2 1.3e-19 70.5 0.2 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.2 EMG48491.1 - 2e-06 27.7 1.2 0.0043 16.9 0.2 2.6 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Ras PF00071.17 EMG48493.1 - 9.5e-56 187.6 0.0 1.1e-55 187.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMG48493.1 - 1.2e-16 61.3 0.0 1.8e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMG48493.1 - 2.3e-07 30.2 0.0 3.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMG48493.1 - 0.0018 17.7 0.0 0.0087 15.5 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EMG48493.1 - 0.0046 16.1 0.0 0.0067 15.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EMG48493.1 - 0.008 15.3 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region C2 PF00168.25 EMG48494.1 - 6.3e-10 38.7 0.0 1.4e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain OrfB_IS605 PF01385.14 EMG48495.1 - 0.011 15.0 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Probable transposase Sec10 PF07393.6 EMG48495.1 - 0.44 8.6 6.8 0.57 8.2 4.7 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 DUF3810 PF12725.2 EMG48495.1 - 0.53 9.1 4.6 0.73 8.6 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Rifin_STEVOR PF02009.11 EMG48495.1 - 3.8 7.0 7.5 5.6 6.5 5.2 1.3 1 0 0 1 1 1 0 Rifin/stevor family DNA_pol_viral_N PF00242.12 EMG48495.1 - 7.6 5.4 10.5 11 4.9 7.2 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 EMG48495.1 - 9.1 4.4 12.3 10 4.2 8.5 1.0 1 0 0 1 1 1 0 Transmembrane protein Hist_deacetyl PF00850.14 EMG48497.1 - 3.9e-76 256.3 0.1 6.4e-76 255.6 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain DUF1256 PF06866.6 EMG48497.1 - 0.029 13.5 0.0 0.21 10.7 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1256) Pro_CA PF00484.14 EMG48498.1 - 1.9e-24 86.3 0.0 2.7e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Glycos_transf_2 PF00535.21 EMG48499.1 - 1.8e-25 89.5 0.0 2.5e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EMG48499.1 - 1.2e-10 41.6 0.0 1.6e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 EMG48499.1 - 0.00048 20.3 0.0 0.0012 19.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 EMG48499.1 - 0.00057 19.0 0.0 0.00077 18.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 mRNA_triPase PF02940.10 EMG48500.1 - 9.1e-15 54.9 3.2 1.2e-14 54.5 2.2 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain PGM_PMM_I PF02878.11 EMG48501.1 - 5.2e-38 129.6 0.2 7.7e-38 129.0 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EMG48501.1 - 8.6e-24 83.7 0.0 1.9e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EMG48501.1 - 1.7e-14 53.9 0.0 4.4e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EMG48501.1 - 3.2e-11 43.0 0.0 8.3e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GATA PF00320.22 EMG48502.1 - 3.9e-15 54.9 2.9 1.2e-14 53.3 2.0 1.9 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 EMG48502.1 - 0.053 12.8 0.2 0.096 12.0 0.1 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding PGA2 PF07543.7 EMG48503.1 - 1.2e-07 31.5 13.0 0.00098 18.9 2.9 2.0 1 1 1 2 2 2 2 Protein trafficking PGA2 FAM183 PF14886.1 EMG48503.1 - 0.015 15.8 2.2 0.024 15.1 1.5 1.4 1 1 0 1 1 1 0 FAM183A and FAM183B related TIMELESS PF04821.9 EMG48503.1 - 0.12 11.5 1.5 0.12 11.5 0.2 1.6 1 1 1 2 2 2 0 Timeless protein DUF4483 PF14825.1 EMG48503.1 - 0.2 11.2 5.6 0.26 10.9 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) SnAC PF14619.1 EMG48503.1 - 5.3 7.2 9.5 3.6e+02 1.3 6.6 2.3 1 1 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex WD40 PF00400.27 EMG48504.1 - 5.7e-23 79.9 4.5 7.5e-06 25.6 0.4 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat RNA_pol_3_Rpc31 PF11705.3 EMG48505.1 - 3e-61 207.3 16.9 3.3e-61 207.1 11.7 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Methyltransf_31 PF13847.1 EMG48506.1 - 6.4e-26 90.7 0.0 8.6e-26 90.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMG48506.1 - 6.3e-25 87.5 0.0 1.5e-24 86.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMG48506.1 - 1e-15 57.8 0.0 1.5e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMG48506.1 - 4.1e-15 55.5 0.0 5.4e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EMG48506.1 - 3.5e-14 52.9 0.0 6.9e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMG48506.1 - 1.4e-13 51.3 0.0 2.2e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMG48506.1 - 1e-12 48.3 0.0 2.1e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMG48506.1 - 3.7e-09 36.6 0.0 6.9e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMG48506.1 - 7.9e-09 35.3 0.0 1.1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_29 PF03141.11 EMG48506.1 - 2.4e-05 22.8 0.0 3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.12 EMG48506.1 - 2.7e-05 23.3 0.0 6e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_PK PF05891.7 EMG48506.1 - 0.0001 21.7 0.0 0.00019 20.7 0.0 1.5 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase MTS PF05175.9 EMG48506.1 - 0.00015 21.2 0.0 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 EMG48506.1 - 0.0018 17.6 0.0 0.013 14.8 0.0 2.0 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.6 EMG48506.1 - 0.0027 16.4 0.0 0.0038 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) DREV PF05219.7 EMG48506.1 - 0.0069 15.3 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_8 PF05148.10 EMG48506.1 - 0.052 13.1 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase RrnaAD PF00398.15 EMG48506.1 - 0.056 12.4 0.0 0.099 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PrmA PF06325.8 EMG48506.1 - 0.064 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NAS PF03059.11 EMG48506.1 - 0.086 11.9 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Nicotianamine synthase protein Methyltransf_16 PF10294.4 EMG48506.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Zn_clus PF00172.13 EMG48507.1 - 1.1e-07 31.6 9.5 1.1e-07 31.6 6.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med5 PF08689.5 EMG48508.1 - 1.2e-80 271.4 63.3 2.2e-65 221.0 16.5 3.0 2 1 1 3 3 3 3 Mediator complex subunit Med5 Pex14_N PF04695.8 EMG48510.1 - 6.5e-42 142.8 0.1 6.5e-42 142.8 0.1 3.8 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CR6_interact PF10147.4 EMG48510.1 - 0.004 16.5 0.1 0.004 16.5 0.1 2.1 2 1 0 2 2 2 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Tox-WTIP PF15654.1 EMG48510.1 - 0.0098 15.4 0.5 0.026 14.1 0.3 1.7 1 0 0 1 1 1 1 Toxin with a conserved tryptophan and TIP tripeptide motif Baculo_PEP_C PF04513.7 EMG48510.1 - 0.073 12.8 8.6 0.14 11.9 5.9 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EMG48510.1 - 0.32 10.5 3.4 0.16 11.5 0.2 2.0 2 0 0 2 2 2 0 IncA protein Fzo_mitofusin PF04799.8 EMG48510.1 - 0.88 8.9 5.9 3.1 7.1 0.7 2.3 2 0 0 2 2 2 0 fzo-like conserved region FliD_N PF02465.13 EMG48510.1 - 2.7 8.4 18.4 2 8.8 0.4 4.3 4 1 0 4 4 4 0 Flagellar hook-associated protein 2 N-terminus Mito_carr PF00153.22 EMG48511.1 - 1.8e-49 165.3 0.2 1.6e-15 56.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Prenyltrans PF00432.16 EMG48512.1 - 2.2e-23 81.4 8.3 1.3e-08 34.2 0.0 5.9 6 1 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EMG48512.1 - 1.7e-16 60.6 0.0 8.1e-05 22.9 0.0 3.8 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EMG48512.1 - 0.00024 21.0 0.0 0.29 11.1 0.0 2.9 3 0 0 3 3 3 2 Prenyltransferase-like MUG2_C PF08593.5 EMG48514.1 - 0.062 13.5 0.5 0.17 12.1 0.0 1.9 2 0 0 2 2 2 0 Meiotically up-regulated glycoproteins C-terminal Fer2_3 PF13085.1 EMG48515.1 - 5.7e-32 109.8 0.1 1e-31 109.0 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EMG48515.1 - 4.6e-10 39.6 7.3 4.6e-10 39.6 5.1 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EMG48515.1 - 6.7e-09 35.6 5.8 6.7e-09 35.6 4.1 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EMG48515.1 - 1.5e-05 25.2 2.6 1.5e-05 25.2 1.8 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EMG48515.1 - 0.00022 20.9 5.3 0.00022 20.9 3.7 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EMG48515.1 - 0.0029 17.3 1.0 0.0029 17.3 0.7 2.7 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.1 EMG48515.1 - 0.0052 17.0 10.1 0.038 14.2 0.2 3.2 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 EMG48515.1 - 0.021 15.2 7.4 0.021 15.2 5.1 2.9 2 2 1 3 3 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.1 EMG48515.1 - 2.2 9.0 11.6 9.2 7.1 0.3 3.5 3 1 0 3 3 3 0 4Fe-4S double cluster binding domain Fer4_15 PF13459.1 EMG48515.1 - 2.3 8.8 7.9 2.4 8.7 0.2 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain ABC_tran_2 PF12848.2 EMG48516.1 - 0.0085 15.9 2.1 0.014 15.2 1.5 1.3 1 0 0 1 1 1 1 ABC transporter Latarcin PF10279.4 EMG48516.1 - 0.08 13.1 0.5 0.14 12.3 0.3 1.4 1 0 0 1 1 1 0 Latarcin precursor MerR-DNA-bind PF09278.6 EMG48516.1 - 0.13 12.6 2.6 0.2 12.0 1.8 1.3 1 0 0 1 1 1 0 MerR, DNA binding Antifungal_prot PF11402.3 EMG48517.1 - 0.12 12.6 2.4 7.1 6.9 0.1 2.3 2 0 0 2 2 2 0 Antifungal protein PTPLA PF04387.9 EMG48518.1 - 4.5e-16 58.7 8.2 1.1e-15 57.4 5.7 1.6 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA SAPS PF04499.10 EMG48519.1 - 9e-150 499.4 6.6 9e-150 499.4 4.6 3.3 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein BIR PF00653.16 EMG48520.1 - 6.5e-27 93.7 1.9 1.5e-15 57.3 0.2 2.7 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-BED PF02892.10 EMG48520.1 - 0.0023 17.6 3.5 1.3 8.8 0.1 2.7 2 0 0 2 2 2 2 BED zinc finger Sugar_tr PF00083.19 EMG48521.1 - 1.4e-102 343.6 29.1 1.9e-102 343.2 20.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG48521.1 - 4.9e-27 94.5 48.9 1.2e-18 66.9 17.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMG48521.1 - 3e-06 25.9 34.5 0.00053 18.5 5.3 3.2 2 2 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 EMG48521.1 - 7.1e-05 21.2 2.1 7.1e-05 21.2 1.4 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) RhodobacterPufX PF11511.3 EMG48521.1 - 0.37 10.2 6.7 17 4.8 0.0 3.3 2 0 0 2 2 2 0 Intrinsic membrane protein PufX 2-Hacid_dh_C PF02826.14 EMG48522.1 - 4.9e-35 120.2 0.0 1.7e-34 118.4 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMG48522.1 - 3.5e-17 62.1 0.0 5.2e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMG48522.1 - 0.00026 20.8 0.0 0.00056 19.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EMG48522.1 - 0.077 12.3 0.0 0.17 11.2 0.0 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain RAI1 PF08652.6 EMG48523.1 - 7.3e-14 51.3 0.0 2.1e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease AA_permease PF00324.16 EMG48524.1 - 5.7e-77 259.0 47.1 6.9e-77 258.7 32.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG48524.1 - 1.6e-29 102.6 56.0 2.5e-29 102.0 38.7 1.4 1 1 0 1 1 1 1 Amino acid permease Gln-synt_C PF00120.19 EMG48525.1 - 1.1e-62 211.5 0.0 1.3e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EMG48525.1 - 8.6e-19 66.9 0.0 1.4e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Baculo_PEP_N PF04512.7 EMG48527.1 - 0.095 12.6 1.8 1.1 9.3 0.1 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, N terminus FGGY_C PF02782.11 EMG48528.1 - 6.7e-69 231.4 0.3 1.3e-68 230.5 0.2 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EMG48528.1 - 5.8e-53 179.7 0.1 4.2e-44 150.6 0.0 3.1 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain ROK PF00480.15 EMG48528.1 - 0.089 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 ROK family IPK PF03770.11 EMG48530.1 - 1.4e-49 168.4 0.0 1.4e-49 168.4 0.0 1.8 2 0 0 2 2 2 1 Inositol polyphosphate kinase Clat_adaptor_s PF01217.15 EMG48531.1 - 1.6e-52 176.9 4.1 1.9e-52 176.7 2.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mannosyl_trans3 PF11051.3 EMG48532.1 - 5.8e-88 294.7 0.0 2.3e-87 292.7 0.0 2.0 2 0 0 2 2 2 1 Mannosyltransferase putative ADH_N PF08240.7 EMG48536.1 - 2.4e-28 98.0 4.1 3.7e-28 97.4 2.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMG48536.1 - 7e-14 51.4 0.0 1.1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 EMG48536.1 - 0.042 13.9 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMG48536.1 - 0.15 10.8 0.1 0.23 10.3 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pox_T4_C PF04490.7 EMG48537.1 - 0.085 12.6 2.1 0.099 12.3 1.4 1.0 1 0 0 1 1 1 0 Poxvirus T4 protein, C terminus PBD PF00786.23 EMG48537.1 - 0.18 12.2 0.7 0.28 11.6 0.1 1.6 1 1 1 2 2 2 0 P21-Rho-binding domain SR-25 PF10500.4 EMG48537.1 - 2.1 7.7 15.9 2.5 7.5 11.0 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FMN_red PF03358.10 EMG48539.1 - 1.8e-09 37.2 0.0 4.3e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 EMG48539.1 - 0.00049 20.1 0.1 0.0011 18.9 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin Flavodoxin_2 PF02525.12 EMG48539.1 - 0.0027 17.2 0.1 0.0094 15.4 0.0 1.8 1 1 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 EMG48539.1 - 0.03 14.3 0.0 0.37 10.7 0.0 2.2 2 0 0 2 2 2 0 Flavodoxin domain MDFI PF15316.1 EMG48539.1 - 0.35 10.8 3.5 0.51 10.2 2.4 1.3 1 0 0 1 1 1 0 MyoD family inhibitor zf-RING_2 PF13639.1 EMG48540.1 - 2.7e-12 46.3 4.9 4.8e-12 45.5 3.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMG48540.1 - 9.2e-08 32.0 2.1 1.9e-07 31.0 1.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMG48540.1 - 1.1e-07 31.7 7.2 2.7e-07 30.4 5.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMG48540.1 - 1.7e-07 30.7 5.8 3.1e-07 29.9 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMG48540.1 - 5.5e-07 29.2 5.0 9.7e-07 28.4 3.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMG48540.1 - 2.9e-06 26.8 3.3 5.4e-06 25.9 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.17 EMG48540.1 - 3.8e-05 23.3 0.0 7.9e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-Apc11 PF12861.2 EMG48540.1 - 0.00049 19.8 1.0 0.001 18.8 0.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EMG48540.1 - 0.16 12.0 5.2 0.31 11.1 3.6 1.5 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.3 EMG48540.1 - 0.38 10.3 4.2 0.78 9.3 2.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 EMG48540.1 - 0.77 9.7 7.1 2.3 8.2 3.9 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EMG48540.1 - 2.5 7.9 8.2 0.53 10.0 3.0 2.0 2 0 0 2 2 2 0 RING-type zinc-finger C1_3 PF07649.7 EMG48540.1 - 7 6.7 13.6 15 5.7 0.5 3.5 3 0 0 3 3 3 0 C1-like domain Noc2 PF03715.8 EMG48541.1 - 6.4e-128 425.8 4.6 6.4e-128 425.8 3.2 2.4 3 0 0 3 3 3 1 Noc2p family Zn_clus PF00172.13 EMG48542.1 - 1.5e-05 24.8 6.5 2.9e-05 23.8 4.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 EMG48542.1 - 0.16 10.1 80.8 0.0081 14.4 29.7 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Spore_coat_CotO PF14153.1 EMG48542.1 - 0.28 10.5 33.5 0.32 10.4 11.4 3.2 3 0 0 3 3 3 0 Spore coat protein CotO Peptidase_S15 PF02129.13 EMG48542.1 - 4.4 6.6 15.6 2.8 7.2 5.4 2.3 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Glutaredoxin PF00462.19 EMG48543.1 - 0.0013 18.6 0.1 0.0021 18.0 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF1462 PF07315.6 EMG48543.1 - 0.11 12.4 1.5 0.14 12.1 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1462) XPG_N PF00752.12 EMG48544.1 - 0.032 14.4 0.0 0.044 14.0 0.0 1.2 1 0 0 1 1 1 0 XPG N-terminal domain Mito_carr PF00153.22 EMG48545.1 - 7.8e-68 224.2 2.7 2.8e-24 84.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RIIa PF02197.12 EMG48545.1 - 0.084 12.3 0.0 7.6 6.0 0.0 2.4 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit ADH_N PF08240.7 EMG48546.1 - 2.1e-25 88.5 3.9 3.7e-25 87.8 2.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMG48546.1 - 1.6e-16 59.9 0.0 2.5e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_6 PF00970.19 EMG48546.1 - 0.013 15.6 0.0 13 5.9 0.0 3.1 3 0 0 3 3 3 0 Oxidoreductase FAD-binding domain DAO PF01266.19 EMG48546.1 - 0.03 13.2 0.6 0.051 12.4 0.4 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EMG48546.1 - 0.064 12.2 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EMG48546.1 - 0.091 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMG48546.1 - 0.1 12.6 1.1 0.38 10.8 0.1 2.3 2 1 1 3 3 3 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EMG48546.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF2407_C PF13373.1 EMG48547.1 - 3.2e-47 159.9 0.1 5.5e-47 159.2 0.1 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EMG48547.1 - 5.2e-19 68.2 0.1 1.2e-18 67.0 0.1 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EMG48547.1 - 0.03 14.2 0.1 0.05 13.4 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EMG48547.1 - 0.053 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family DUF4257 PF14074.1 EMG48547.1 - 0.093 12.3 0.1 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4257) DUF543 PF04418.7 EMG48547.1 - 0.1 12.5 0.0 0.3 11.0 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF543) Glycophorin_A PF01102.13 EMG48547.1 - 0.12 12.1 0.0 0.5 10.1 0.0 1.8 2 0 0 2 2 2 0 Glycophorin A MTP18 PF10558.4 EMG48548.1 - 2.1e-62 209.4 0.3 2.5e-62 209.1 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) 3-HAO PF06052.7 EMG48549.1 - 1.1e-65 219.6 0.1 1.2e-65 219.5 0.1 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EMG48549.1 - 1.8e-06 27.3 0.1 2.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Cupin domain zf-ribbon_3 PF13248.1 EMG48549.1 - 0.029 13.5 0.9 0.83 8.9 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Rpr2 PF04032.11 EMG48549.1 - 0.065 13.1 0.3 1 9.2 0.2 2.2 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.2 EMG48549.1 - 0.14 11.9 2.5 0.31 10.8 0.9 2.1 2 1 0 2 2 2 0 Double zinc ribbon zf-RanBP PF00641.13 EMG48549.1 - 0.4 9.8 5.4 2.2 7.4 0.3 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Glutaredoxin PF00462.19 EMG48550.1 - 0.0077 16.1 0.3 0.032 14.2 0.1 2.1 2 0 0 2 2 2 1 Glutaredoxin Haemocyan_bet_s PF14830.1 EMG48551.1 - 0.078 12.6 0.1 0.57 9.9 0.0 2.0 2 0 0 2 2 2 0 Haemocyanin beta-sandwich DUF1741 PF08427.5 EMG48552.1 - 3.3e-06 26.7 2.6 3.3e-06 26.7 1.8 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1741) TFIIB PF00382.14 EMG48553.1 - 3.8e-33 113.0 0.1 1.7e-18 66.2 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EMG48553.1 - 2.4e-13 49.1 0.6 4.6e-13 48.2 0.4 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Trp_repressor PF01371.14 EMG48553.1 - 0.0012 18.6 1.1 0.04 13.8 0.0 2.4 2 0 0 2 2 2 1 Trp repressor protein Cyclin_C PF02984.14 EMG48553.1 - 0.0063 16.4 0.2 0.09 12.7 0.0 2.5 2 1 1 3 3 3 1 Cyclin, C-terminal domain Cyclin_N PF00134.18 EMG48553.1 - 0.072 12.6 0.0 0.68 9.5 0.0 2.1 1 1 1 2 2 2 0 Cyclin, N-terminal domain zf-ribbon_3 PF13248.1 EMG48553.1 - 0.44 9.8 2.4 0.32 10.2 0.2 2.0 2 0 0 2 2 2 0 zinc-ribbon domain DPPIV_N PF00930.16 EMG48554.1 - 8.8e-65 218.5 10.0 1.5e-64 217.8 6.9 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EMG48554.1 - 4.9e-45 153.3 0.0 8.8e-45 152.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMG48554.1 - 9.5e-07 28.6 0.0 1.6e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMG48554.1 - 0.00023 21.1 0.0 0.0052 16.7 0.0 2.2 1 1 0 2 2 2 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 EMG48554.1 - 0.0013 17.0 0.0 0.0027 16.0 0.0 1.4 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.15 EMG48554.1 - 0.0018 17.7 0.0 0.0035 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative esterase BRCA-2_OB1 PF09103.5 EMG48554.1 - 0.033 13.8 0.0 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 RNA_pol_Rpb2_6 PF00562.23 EMG48555.1 - 1.9e-116 389.0 0.5 3.1e-116 388.3 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EMG48555.1 - 5.8e-59 198.4 1.8 8.3e-58 194.6 0.5 2.2 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EMG48555.1 - 3.5e-39 134.1 1.8 6.7e-39 133.2 1.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EMG48555.1 - 1.8e-30 105.0 0.1 4.4e-30 103.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EMG48555.1 - 4.9e-28 96.7 0.2 5e-27 93.4 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EMG48555.1 - 8.8e-19 67.0 0.0 1.8e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EMG48555.1 - 1.4e-12 47.3 0.2 3.7e-12 46.0 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 EMG48555.1 - 0.0012 17.3 0.2 0.0022 16.4 0.1 1.3 1 0 0 1 1 1 1 Baculovirus Y142 protein DUF1528 PF07515.6 EMG48555.1 - 0.094 12.7 0.2 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1528) Flavodoxin_1 PF00258.20 EMG48556.1 - 0.025 14.5 0.0 0.028 14.4 0.0 1.0 1 0 0 1 1 1 0 Flavodoxin Ribonuc_red_lgC PF02867.10 EMG48557.1 - 3.9e-214 712.1 0.0 4.8e-214 711.8 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EMG48557.1 - 2.5e-22 78.4 0.1 1.2e-21 76.2 0.1 2.2 3 0 0 3 3 3 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EMG48557.1 - 2e-05 24.9 0.1 8.6e-05 22.8 0.0 2.1 1 0 0 1 1 1 1 ATP cone domain Tfb2 PF03849.9 EMG48558.1 - 2.7e-154 513.2 0.5 2.7e-154 513.2 0.3 1.4 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EMG48558.1 - 0.00014 21.6 0.0 0.00036 20.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Mei5 PF10376.4 EMG48559.1 - 1.8e-07 30.9 15.3 5.3e-06 26.1 3.8 2.6 1 1 1 2 2 2 2 Double-strand recombination repair protein SDA1 PF05285.7 EMG48560.1 - 4.8e-102 341.5 32.2 4.8e-102 341.5 22.3 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 EMG48560.1 - 1.3e-24 86.2 0.8 4.9e-24 84.3 0.1 2.3 2 0 0 2 2 2 1 NUC130/3NT domain TFIIB PF00382.14 EMG48561.1 - 7.2e-51 169.8 1.6 9.3e-26 89.4 0.2 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EMG48561.1 - 1.1e-26 92.9 3.4 1.1e-26 92.9 2.3 2.8 3 0 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EMG48561.1 - 7e-10 38.0 0.8 1.2e-09 37.2 0.5 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 EMG48561.1 - 2.1e-06 27.3 0.6 0.035 13.6 0.1 2.9 2 0 0 2 2 2 2 Cyclin, N-terminal domain DZR PF12773.2 EMG48561.1 - 0.027 14.3 0.6 0.053 13.3 0.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 EMG48561.1 - 0.033 14.1 1.2 0.078 12.9 0.5 1.9 2 0 0 2 2 2 0 Zinc ribbon domain hNIFK_binding PF12196.3 EMG48561.1 - 0.088 12.2 1.6 0.22 10.9 1.1 1.7 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK RRN7 PF11781.3 EMG48561.1 - 0.1 12.0 4.4 0.23 10.9 3.0 1.6 1 1 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 A2L_zn_ribbon PF08792.5 EMG48561.1 - 0.2 11.1 2.1 1.3 8.5 0.4 2.5 2 0 0 2 2 2 0 A2L zinc ribbon domain zinc_ribbon_5 PF13719.1 EMG48561.1 - 0.32 10.6 2.3 16 5.1 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EMG48561.1 - 0.53 10.0 2.7 18 5.0 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain FYDLN_acid PF09538.5 EMG48561.1 - 1 9.9 0.0 1 9.9 0.0 3.6 3 1 0 3 3 2 0 Protein of unknown function (FYDLN_acid) DUF202 PF02656.10 EMG48562.1 - 4.2e-09 36.5 0.0 5.3e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Siah-Interact_N PF09032.6 EMG48562.1 - 0.072 13.1 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Siah interacting protein, N terminal DEAD PF00270.24 EMG48563.1 - 5.8e-42 143.0 0.0 6.1e-41 139.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG48563.1 - 3.5e-28 97.2 0.1 1.2e-27 95.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMG48563.1 - 1.1e-05 25.3 0.3 9.5e-05 22.2 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EMG48563.1 - 0.049 12.9 3.8 1.6 7.9 0.1 2.9 2 1 0 2 2 2 0 SecA DEAD-like domain GTP1_OBG PF01018.17 EMG48564.1 - 9.3e-30 103.3 3.7 7.7e-21 74.3 1.2 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EMG48564.1 - 5.8e-21 74.6 0.0 1.8e-20 73.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMG48564.1 - 5.9e-08 32.1 0.0 1.1e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.16 EMG48564.1 - 4e-05 22.9 0.0 0.00013 21.2 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family Dynamin_N PF00350.18 EMG48564.1 - 0.0032 17.3 0.2 2.9 7.6 0.0 2.8 2 1 1 3 3 3 2 Dynamin family Miro PF08477.8 EMG48564.1 - 0.048 14.1 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Response_reg PF00072.19 EMG48565.1 - 3.6e-14 52.7 0.1 5.5e-14 52.1 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Cwf_Cwc_15 PF04889.7 EMG48565.1 - 0.15 11.7 9.5 0.21 11.2 6.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ATG27 PF09451.5 EMG48565.1 - 0.2 10.8 2.9 0.3 10.2 2.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 Nucleoplasmin PF03066.10 EMG48565.1 - 0.84 9.1 5.9 1.4 8.4 4.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 EMG48565.1 - 0.97 8.0 11.3 1.2 7.8 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 EMG48565.1 - 9.2 5.4 10.0 13 4.9 6.9 1.2 1 0 0 1 1 1 0 NOA36 protein Glyco_transf_20 PF00982.16 EMG48566.1 - 1.5e-203 676.6 0.0 1.7e-203 676.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 EMG48566.1 - 1.5e-05 24.4 0.4 0.021 14.2 0.0 2.8 2 1 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EMG48566.1 - 0.044 13.2 0.1 0.089 12.2 0.0 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain YIF1 PF03878.10 EMG48567.1 - 1.4e-49 168.4 1.1 2.2e-49 167.7 0.8 1.2 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EMG48567.1 - 0.0041 16.6 0.1 0.0068 15.9 0.1 1.3 1 0 0 1 1 1 1 Yip1 domain PAT1 PF09770.4 EMG48567.1 - 0.18 10.0 23.7 0.21 9.8 16.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDK5_activator PF03261.10 EMG48567.1 - 5.2 6.3 9.5 6.7 5.9 6.6 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Acyl_transf_1 PF00698.16 EMG48568.1 - 5.1e-18 65.4 0.0 6.3e-18 65.1 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain HMG_box PF00505.14 EMG48569.1 - 3.6e-07 30.3 3.3 3.6e-07 30.3 2.3 2.6 2 0 0 2 2 2 1 HMG (high mobility group) box Cnd1_N PF12922.2 EMG48569.1 - 9.6 5.8 11.5 1.2 8.6 0.2 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term Vezatin PF12632.2 EMG48571.1 - 1.3e-40 139.0 20.9 1.3e-40 139.0 14.5 3.0 3 1 0 3 3 3 1 Mysoin-binding motif of peroxisomes TOM13 PF08219.6 EMG48571.1 - 0.043 13.5 0.6 0.84 9.4 0.2 3.2 2 0 0 2 2 2 0 Outer membrane protein TOM13 LisH PF08513.6 EMG48572.1 - 6.6e-05 22.5 0.8 0.00011 21.7 0.6 1.4 1 0 0 1 1 1 1 LisH F-box-like PF12937.2 EMG48573.1 - 2.2e-05 24.0 0.6 8.9e-05 22.1 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMG48573.1 - 0.0041 16.7 0.1 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain Aldedh PF00171.17 EMG48574.1 - 5.3e-181 601.9 0.9 6e-181 601.7 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMG48574.1 - 1.1e-06 27.7 0.0 1.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Beta_elim_lyase PF01212.16 EMG48575.1 - 1.8e-74 250.4 0.0 2.2e-74 250.1 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EMG48575.1 - 1.1e-06 27.8 0.0 1.4e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EMG48575.1 - 0.1 11.5 0.1 0.49 9.3 0.0 1.9 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF1811 PF08838.5 EMG48575.1 - 0.15 12.0 0.8 0.24 11.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) 2-Hacid_dh_C PF02826.14 EMG48576.1 - 1.2e-09 37.6 0.0 6.9e-09 35.0 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 EMG48576.1 - 0.0047 16.7 0.0 0.95 9.2 0.0 2.0 1 1 1 2 2 2 2 ThiF family Polysacc_synt_2 PF02719.10 EMG48576.1 - 0.073 11.9 0.0 0.078 11.8 0.0 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.13 EMG48576.1 - 0.097 12.6 0.1 0.68 9.9 0.0 1.9 1 1 1 2 2 2 0 TrkA-N domain 2-Hacid_dh PF00389.25 EMG48577.1 - 3e-17 62.3 0.0 3.2e-17 62.2 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain UDPGP PF01704.13 EMG48578.1 - 2.2e-186 619.4 0.0 2.6e-186 619.2 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase TBCA PF02970.11 EMG48579.1 - 4.5e-30 103.5 13.4 5e-30 103.4 9.3 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor A Phage_GP20 PF06810.6 EMG48579.1 - 0.0082 15.5 10.7 0.012 15.0 7.4 1.3 1 0 0 1 1 1 1 Phage minor structural protein GP20 Arfaptin PF06456.8 EMG48579.1 - 0.0093 15.3 2.1 0.013 14.8 1.2 1.4 1 1 0 1 1 1 1 Arfaptin-like domain Dna2 PF08696.6 EMG48579.1 - 0.019 14.2 2.4 0.023 13.9 1.7 1.1 1 0 0 1 1 1 0 DNA replication factor Dna2 NusB PF01029.13 EMG48579.1 - 0.02 14.8 3.9 0.024 14.6 2.7 1.1 1 0 0 1 1 1 0 NusB family Rab5-bind PF09311.6 EMG48579.1 - 0.022 14.6 6.5 0.025 14.4 4.5 1.1 1 0 0 1 1 1 0 Rabaptin-like protein DUF2075 PF09848.4 EMG48579.1 - 0.033 13.1 2.6 0.036 13.0 1.8 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF342 PF03961.8 EMG48579.1 - 0.036 12.4 8.4 0.04 12.3 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PSII_Pbs27 PF13326.1 EMG48579.1 - 0.042 13.8 0.3 0.058 13.3 0.2 1.4 1 1 0 1 1 1 0 Photosystem II Pbs27 WHEP-TRS PF00458.15 EMG48579.1 - 0.093 12.4 2.5 0.23 11.1 1.4 2.0 1 1 1 2 2 2 0 WHEP-TRS domain Ribosomal_L13 PF00572.13 EMG48579.1 - 0.13 12.3 2.3 0.16 12.0 1.6 1.1 1 0 0 1 1 1 0 Ribosomal protein L13 DUF2191 PF09957.4 EMG48579.1 - 0.13 12.0 2.5 13 5.7 0.2 2.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2191) DUF1501 PF07394.7 EMG48579.1 - 0.19 10.4 0.9 0.18 10.6 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF4535 PF15054.1 EMG48579.1 - 0.21 11.0 1.4 0.26 10.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4535) HSP70 PF00012.15 EMG48579.1 - 0.24 9.2 7.5 0.24 9.2 5.2 1.0 1 0 0 1 1 1 0 Hsp70 protein Tho2 PF11262.3 EMG48579.1 - 0.28 10.2 5.8 0.31 10.0 4.0 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF2664 PF10867.3 EMG48579.1 - 0.29 11.7 3.8 1.4 9.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2664) DUF2361 PF10153.4 EMG48579.1 - 0.32 11.2 7.6 0.36 11.0 5.3 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) IncA PF04156.9 EMG48579.1 - 0.32 10.5 7.5 0.37 10.3 5.2 1.1 1 0 0 1 1 1 0 IncA protein Mnd1 PF03962.10 EMG48579.1 - 0.35 10.5 8.5 0.4 10.3 5.9 1.0 1 0 0 1 1 1 0 Mnd1 family Med11 PF10280.4 EMG48579.1 - 0.53 10.3 4.9 1 9.4 3.4 1.5 1 1 0 1 1 1 0 Mediator complex protein Fzo_mitofusin PF04799.8 EMG48579.1 - 0.59 9.4 4.3 0.67 9.3 3.0 1.2 1 0 0 1 1 1 0 fzo-like conserved region LMBR1 PF04791.11 EMG48579.1 - 0.66 8.4 4.2 0.77 8.2 2.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein PFEMP PF03011.10 EMG48579.1 - 1.2 9.5 7.1 1.3 9.3 4.9 1.1 1 0 0 1 1 1 0 PFEMP DBL domain DUF2570 PF10828.3 EMG48579.1 - 1.3 8.7 8.3 1.9 8.1 5.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) Noc2 PF03715.8 EMG48579.1 - 1.7 7.4 5.5 2 7.2 3.8 1.0 1 0 0 1 1 1 0 Noc2p family DUF2203 PF09969.4 EMG48579.1 - 1.8 8.8 6.3 19 5.4 4.2 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) TMPIT PF07851.8 EMG48579.1 - 2.5 7.1 6.6 2.8 6.9 4.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein MRP-S26 PF14943.1 EMG48579.1 - 2.6 7.5 13.2 1.4 8.4 3.1 2.0 1 1 1 2 2 2 0 Mitochondrial ribosome subunit S26 V_ATPase_I PF01496.14 EMG48579.1 - 3.2 5.5 7.3 3.4 5.4 5.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF896 PF05979.7 EMG48579.1 - 4 7.0 8.8 1.8 8.2 2.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF896) APG6 PF04111.7 EMG48579.1 - 6.4 5.7 11.5 6.9 5.6 8.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DIT1_PvcA PF05141.7 EMG48580.1 - 2.4e-105 351.8 0.0 3e-105 351.5 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein p450 PF00067.17 EMG48581.1 - 5e-45 153.8 0.0 1.9e-44 151.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_A2E PF12382.3 EMG48581.1 - 0.055 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon peptidase Ecm29 PF13001.2 EMG48581.1 - 0.11 10.9 0.2 0.16 10.3 0.1 1.1 1 0 0 1 1 1 0 Proteasome stabiliser MFS_1 PF07690.11 EMG48582.1 - 6e-44 150.1 31.3 6e-44 150.1 21.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG48582.1 - 6.4e-18 64.5 26.8 4e-17 61.9 18.6 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.3 EMG48583.1 - 1.7e-114 382.9 22.5 2e-114 382.7 15.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like CTV_P6 PF06706.6 EMG48583.1 - 2 7.9 6.1 0.45 10.0 0.9 2.4 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein Cupin_8 PF13621.1 EMG48584.1 - 2.2e-13 50.2 0.2 2.2e-13 50.2 0.1 1.8 2 0 0 2 2 2 1 Cupin-like domain JmjC PF02373.17 EMG48584.1 - 6.8e-10 39.1 0.7 2.5e-08 34.1 0.5 2.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 EMG48584.1 - 1.4e-08 34.3 0.2 3.9e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMG48584.1 - 0.00013 21.5 0.0 0.00047 19.7 0.0 2.0 1 0 0 1 1 1 1 F-box domain 2-Hacid_dh_C PF02826.14 EMG48585.1 - 1.2e-09 37.6 0.0 6.9e-09 35.0 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 EMG48585.1 - 0.0047 16.7 0.0 0.95 9.2 0.0 2.0 1 1 1 2 2 2 2 ThiF family Polysacc_synt_2 PF02719.10 EMG48585.1 - 0.073 11.9 0.0 0.078 11.8 0.0 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.13 EMG48585.1 - 0.097 12.6 0.1 0.68 9.9 0.0 1.9 1 1 1 2 2 2 0 TrkA-N domain 2-Hacid_dh PF00389.25 EMG48586.1 - 3e-17 62.3 0.0 3.2e-17 62.2 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Ndc80_HEC PF03801.8 EMG48587.1 - 1.6e-47 160.8 3.3 1.6e-47 160.8 2.3 2.4 2 0 0 2 2 2 1 HEC/Ndc80p family DUF2703 PF10865.3 EMG48587.1 - 0.093 12.6 3.9 0.053 13.4 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) Ubiquitin_2 PF14560.1 EMG48588.1 - 1.4e-27 95.7 0.1 2.6e-27 94.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.20 EMG48588.1 - 3.4e-23 81.1 1.4 4.9e-23 80.6 1.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Glyco_hydro_2 PF00703.16 EMG48589.1 - 1.9e-08 34.6 0.0 4.3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EMG48589.1 - 0.0028 17.2 0.0 0.011 15.2 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EMG48589.1 - 0.018 13.9 0.1 0.049 12.5 0.1 1.6 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain OPT PF03169.10 EMG48591.1 - 6.6e-178 593.0 40.8 7.7e-178 592.7 28.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.10 EMG48592.1 - 1.6e-173 578.5 40.1 1.9e-173 578.3 27.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein RNA_pol_Rpc82 PF05645.8 EMG48593.1 - 1.5e-63 214.7 0.1 2.6e-63 213.9 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EMG48593.1 - 3.3e-20 71.7 0.9 2.8e-19 68.7 0.1 2.6 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EMG48593.1 - 2e-07 30.4 1.2 0.00091 18.7 0.0 3.1 3 0 0 3 3 3 2 TFIIE alpha subunit TrmB PF01978.14 EMG48593.1 - 0.00037 20.1 0.2 0.016 14.9 0.0 2.9 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.1 EMG48593.1 - 0.0087 15.4 4.2 0.009 15.3 1.2 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MIP PF00230.15 EMG48595.1 - 2.3e-42 144.9 15.0 2.7e-42 144.7 10.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein ATG13 PF10033.4 EMG48596.1 - 1.2e-75 253.9 1.5 1.2e-75 253.9 1.0 2.0 2 0 0 2 2 2 1 Autophagy-related protein 13 Cache_3 PF14827.1 EMG48596.1 - 0.026 14.4 0.0 0.073 12.9 0.0 1.7 1 0 0 1 1 1 0 Sensory domain of two-component sensor kinase SRP40_C PF05022.7 EMG48597.1 - 8e-31 106.3 4.2 1.8e-30 105.2 2.9 1.6 1 0 0 1 1 1 1 SRP40, C-terminal domain Utp14 PF04615.8 EMG48597.1 - 2 6.4 50.4 2.5 6.1 34.9 1.1 1 0 0 1 1 1 0 Utp14 protein dsrm PF00035.20 EMG48598.1 - 3.4e-12 46.7 6.1 2.2e-08 34.5 0.1 3.0 3 0 0 3 3 3 2 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 EMG48598.1 - 2.5e-06 27.4 0.0 5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Nucleic_acid_bd PF13820.1 EMG48598.1 - 5.3e-05 22.8 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 Putative nucleic acid-binding region Muted PF14942.1 EMG48598.1 - 0.064 13.1 0.0 4.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Helicase_C_3 PF13625.1 EMG48599.1 - 1.3e-26 92.8 0.1 6.7e-26 90.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMG48599.1 - 2e-14 53.8 1.3 4.3e-14 52.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EMG48599.1 - 4e-12 45.5 0.0 7.2e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMG48599.1 - 1.7e-11 43.8 0.0 4e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMG48599.1 - 2.5e-08 33.6 0.0 5.5e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SBP_bac_6 PF13343.1 EMG48599.1 - 0.031 13.5 0.2 0.093 12.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein AAA_34 PF13872.1 EMG48599.1 - 0.067 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Voldacs PF03517.8 EMG48600.1 - 0.15 11.8 6.5 0.29 10.9 3.4 2.1 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling Ribosomal_S21 PF01165.15 EMG48601.1 - 6.9e-12 44.6 5.6 1.2e-11 43.8 3.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 Mito_carr PF00153.22 EMG48602.1 - 5.5e-42 141.3 3.2 1.6e-17 62.9 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein DmpG_comm PF07836.6 EMG48602.1 - 1.2 8.6 2.9 2.8 7.4 0.1 2.6 3 0 0 3 3 3 0 DmpG-like communication domain Gtr1_RagA PF04670.7 EMG48604.1 - 2.1e-54 184.1 0.9 3.3e-54 183.4 0.6 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region eRF1_1 PF03463.10 EMG48605.1 - 5.8e-29 100.3 1.3 1.2e-28 99.3 0.9 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 EMG48605.1 - 2.2e-25 89.4 0.1 4.1e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EMG48605.1 - 3.3e-24 85.3 0.0 1.1e-23 83.6 0.0 2.0 1 0 0 1 1 1 1 eRF1 domain 3 tRNA_bind PF01588.15 EMG48606.1 - 9e-28 95.9 0.5 2e-27 94.8 0.0 1.8 2 0 0 2 2 2 1 Putative tRNA binding domain GST_C_3 PF14497.1 EMG48606.1 - 2.3e-05 24.7 0.1 0.00024 21.5 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain NARP1 PF12569.3 EMG48606.1 - 0.43 9.2 9.7 0.61 8.7 6.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PAS PF00989.19 EMG48607.1 - 7.9e-07 28.8 0.0 1.8e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.13 EMG48607.1 - 4.2e-06 26.5 13.1 8.8e-06 25.5 9.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_9 PF13426.1 EMG48607.1 - 0.077 13.3 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 PAS domain Sugar_tr PF00083.19 EMG48608.1 - 7.2e-86 288.5 17.2 1e-85 288.0 11.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG48608.1 - 2.6e-27 95.4 27.9 2.9e-27 95.3 16.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 EMG48608.1 - 1e-06 27.6 0.8 1e-06 27.6 0.6 2.2 4 0 0 4 4 4 1 Protein of unknown function (DUF791) TRI12 PF06609.8 EMG48608.1 - 2.5e-06 25.9 2.7 2.5e-06 25.9 1.8 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EMG48608.1 - 0.00075 19.2 0.2 0.27 11.0 0.0 2.9 2 0 0 2 2 2 2 MFS_1 like family KfrA_N PF11740.3 EMG48608.1 - 0.1 13.0 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Ribosomal_L18e PF00828.14 EMG48609.1 - 1e-34 119.6 0.3 1.4e-34 119.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 HD_3 PF13023.1 EMG48610.1 - 3.8e-37 127.5 0.0 5.1e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EMG48610.1 - 4.6e-05 23.4 0.2 0.00012 22.0 0.2 1.7 1 1 0 1 1 1 1 HD domain Evr1_Alr PF04777.8 EMG48611.1 - 9.5e-31 105.5 3.8 9.5e-31 105.5 2.6 1.5 2 0 0 2 2 2 1 Erv1 / Alr family zf-FCS PF06467.9 EMG48611.1 - 0.32 10.6 2.9 1.6 8.4 0.3 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Cass2 PF14526.1 EMG48612.1 - 0.034 14.1 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 Integron-associated effector binding protein FANCL_C PF11793.3 EMG48612.1 - 0.13 12.1 0.1 1.4 8.9 0.0 2.1 2 0 0 2 2 2 0 FANCL C-terminal domain GTP_cyclohydro2 PF00925.15 EMG48613.1 - 2.5e-56 189.5 0.0 4.7e-51 172.3 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II DUF1115 PF06544.7 EMG48613.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) tRNA-synt_2 PF00152.15 EMG48614.1 - 4.6e-84 282.0 0.9 7.3e-84 281.3 0.6 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EMG48614.1 - 5.6e-08 32.5 0.6 1.2e-07 31.4 0.4 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EMG48614.1 - 0.025 13.7 0.5 1.6 7.8 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) TYW3 PF02676.9 EMG48615.1 - 3.5e-54 183.0 0.0 4.8e-54 182.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 GRIP PF01465.15 EMG48616.1 - 1.1e-16 59.9 0.6 2.9e-16 58.7 0.4 1.8 1 0 0 1 1 1 1 GRIP domain IncA PF04156.9 EMG48616.1 - 2.6e-07 30.4 139.2 0.0022 17.6 8.8 7.3 1 1 5 6 6 6 4 IncA protein ATG16 PF08614.6 EMG48616.1 - 5.8e-06 26.2 29.0 0.00025 20.9 7.5 9.0 2 2 3 7 7 6 2 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EMG48616.1 - 0.00027 20.2 12.2 0.00027 20.2 8.4 5.6 1 1 5 6 6 6 4 Reovirus sigma C capsid protein Spc7 PF08317.6 EMG48616.1 - 0.00049 18.8 19.3 0.00049 18.8 13.4 7.2 1 1 6 7 7 6 3 Spc7 kinetochore protein TMF_TATA_bd PF12325.3 EMG48616.1 - 0.00052 19.7 5.5 0.00052 19.7 3.8 9.4 3 2 6 9 9 9 4 TATA element modulatory factor 1 TATA binding Syntaxin PF00804.20 EMG48616.1 - 0.00098 19.2 8.0 0.00098 19.2 5.6 8.8 3 2 3 7 7 5 1 Syntaxin Filament PF00038.16 EMG48616.1 - 0.0011 18.5 111.0 0.12 11.8 4.9 5.3 2 1 3 5 5 5 3 Intermediate filament protein Tropomyosin_1 PF12718.2 EMG48616.1 - 0.0014 18.4 17.6 0.0014 18.4 12.2 7.6 3 1 5 8 8 6 1 Tropomyosin like FlaC_arch PF05377.6 EMG48616.1 - 0.0017 18.1 4.2 0.0017 18.1 2.9 10.4 6 4 2 10 10 10 1 Flagella accessory protein C (FlaC) DUF948 PF06103.6 EMG48616.1 - 0.0019 18.0 3.7 0.0019 18.0 2.6 9.1 4 3 4 9 9 9 2 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.4 EMG48616.1 - 0.0065 16.3 14.9 0.0065 16.3 10.3 8.5 1 1 7 8 8 8 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 EMG48616.1 - 0.076 10.7 143.5 0.2 9.3 15.1 3.8 1 1 2 3 3 3 0 Myosin tail AAA_13 PF13166.1 EMG48616.1 - 0.8 8.0 130.6 0.18 10.2 13.1 4.7 1 1 2 4 4 4 0 AAA domain SNARE PF05739.14 EMG48617.1 - 1.7e-07 30.7 7.1 1.7e-07 30.7 4.9 2.8 3 0 0 3 3 3 1 SNARE domain YjcZ PF13990.1 EMG48617.1 - 0.0073 15.4 1.7 0.009 15.1 0.6 1.5 2 0 0 2 2 2 1 YjcZ-like protein Pex24p PF06398.6 EMG48617.1 - 0.052 12.3 3.5 2.4 6.8 0.1 2.1 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF3901 PF13040.1 EMG48617.1 - 0.13 11.5 3.4 6.1 6.2 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3901) SLY PF12485.3 EMG48617.1 - 0.26 11.5 2.0 0.53 10.5 1.4 1.6 1 1 0 1 1 1 0 Lymphocyte signaling adaptor protein EMP24_GP25L PF01105.19 EMG48617.1 - 1.9 8.1 9.6 0.24 11.0 2.7 2.2 1 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Syntaxin_2 PF14523.1 EMG48617.1 - 3 7.9 13.1 0.67 10.0 4.1 3.0 2 2 0 2 2 2 0 Syntaxin-like protein Fungal_lectin PF07938.7 EMG48618.1 - 0.031 13.5 0.4 0.057 12.6 0.2 1.6 2 0 0 2 2 2 0 Fungal fucose-specific lectin tRNA-synt_1c PF00749.16 EMG48619.1 - 2.1e-102 341.9 0.0 3.5e-102 341.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain AAA_23 PF13476.1 EMG48620.1 - 8.1e-19 68.7 10.2 8.1e-19 68.7 7.1 6.0 2 2 1 3 3 1 1 AAA domain SMC_N PF02463.14 EMG48620.1 - 6.5e-18 64.7 30.7 1.5e-17 63.5 21.2 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EMG48620.1 - 1.2e-06 27.9 0.3 3.5e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain Fib_alpha PF08702.5 EMG48620.1 - 5.9e-05 23.2 62.1 9e-05 22.6 5.0 5.2 3 2 1 5 5 5 3 Fibrinogen alpha/beta chain family AAA_21 PF13304.1 EMG48620.1 - 0.00015 21.8 1.4 0.00015 21.8 1.0 4.1 2 2 1 3 3 3 1 AAA domain AAA_33 PF13671.1 EMG48620.1 - 0.0022 17.8 1.3 0.16 11.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain DUF4200 PF13863.1 EMG48620.1 - 0.003 17.4 6.9 0.003 17.4 4.8 7.6 3 2 2 6 6 3 2 Domain of unknown function (DUF4200) Reo_sigmaC PF04582.7 EMG48620.1 - 0.0055 15.9 3.9 0.0055 15.9 2.7 3.9 3 1 1 4 4 4 1 Reovirus sigma C capsid protein NACHT PF05729.7 EMG48620.1 - 0.0058 16.3 0.2 0.16 11.6 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.1 EMG48620.1 - 0.009 15.4 0.0 0.049 13.0 0.0 2.3 1 0 0 1 1 1 1 AAA domain Baculo_PEP_C PF04513.7 EMG48620.1 - 0.01 15.6 0.6 0.01 15.6 0.4 5.7 4 2 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus MobB PF03205.9 EMG48620.1 - 0.049 13.3 0.1 0.17 11.5 0.1 2.0 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EMG48620.1 - 0.062 13.4 6.4 0.12 12.5 0.1 3.6 2 1 1 3 3 3 0 RNA helicase DUF948 PF06103.6 EMG48620.1 - 0.25 11.2 20.5 0.027 14.3 1.0 4.8 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) AAA_16 PF13191.1 EMG48620.1 - 0.28 11.1 0.0 0.28 11.1 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain DUF812 PF05667.6 EMG48620.1 - 4.1 5.7 76.9 0.088 11.2 6.3 3.8 2 2 2 4 4 4 0 Protein of unknown function (DUF812) AAA_13 PF13166.1 EMG48620.1 - 4.8 5.5 85.8 0.081 11.3 0.1 4.9 3 2 2 5 5 4 0 AAA domain MscS_porin PF12795.2 EMG48620.1 - 5.4 6.2 69.2 0.0089 15.3 13.6 5.6 2 2 2 5 5 5 0 Mechanosensitive ion channel porin domain EF-hand_7 PF13499.1 EMG48621.1 - 3.8e-16 58.9 0.0 4.1e-11 42.8 0.0 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EMG48621.1 - 2.4e-13 48.3 0.1 9e-05 21.5 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EMG48621.1 - 2.7e-13 48.5 0.5 0.00012 21.6 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_9 PF14658.1 EMG48621.1 - 2.5e-11 43.3 0.0 1.5e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EMG48621.1 - 2.6e-08 33.3 0.4 1.5e-06 27.7 0.0 3.1 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 EMG48621.1 - 9.6e-06 24.7 0.5 0.15 11.4 0.0 3.0 3 0 0 3 3 3 2 EF hand UPF0154 PF03672.8 EMG48621.1 - 0.028 14.0 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF211 PF02680.9 EMG48621.1 - 0.034 13.9 0.2 4.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 DUF2305 PF10230.4 EMG48622.1 - 1.5e-62 211.4 0.5 1.8e-62 211.2 0.4 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) NRDE PF05742.7 EMG48623.1 - 5.7e-50 170.1 0.0 3.9e-49 167.4 0.0 1.9 1 1 0 1 1 1 1 NRDE protein RNA_pol_Rpb1_3 PF04983.13 EMG48623.1 - 0.085 12.5 0.0 2.6 7.7 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 3 DUF1752 PF08550.5 EMG48624.1 - 0.0021 17.5 1.9 0.0064 16.0 1.3 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DnaJ PF00226.26 EMG48625.1 - 3.6e-27 93.8 0.8 1.2e-26 92.2 0.6 2.0 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 EMG48625.1 - 1.4e-09 37.7 3.0 3.5e-09 36.5 2.1 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMG48625.1 - 9.8e-07 28.7 1.1 2.2e-06 27.6 0.8 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EMG48625.1 - 0.002 18.1 1.6 0.0075 16.3 1.1 1.9 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Phage_int_SAM_4 PF13495.1 EMG48625.1 - 0.013 15.8 0.6 0.039 14.2 0.4 1.8 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain UPF0167 PF03691.9 EMG48625.1 - 0.015 14.7 0.6 0.037 13.4 0.4 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) G-patch PF01585.18 EMG48626.1 - 3.5e-10 39.4 3.3 7e-10 38.5 2.3 1.5 1 0 0 1 1 1 1 G-patch domain Peptidase_C54 PF03416.14 EMG48627.1 - 1.4e-67 227.7 0.0 9.8e-67 225.0 0.0 2.1 1 1 0 1 1 1 1 Peptidase family C54 Ssu72 PF04722.8 EMG48628.1 - 6.6e-89 296.4 0.6 7.8e-89 296.1 0.4 1.0 1 0 0 1 1 1 1 Ssu72-like protein POP1 PF06978.6 EMG48629.1 - 8e-68 227.7 8.2 1.4e-67 226.9 5.7 1.4 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EMG48629.1 - 1.8e-22 78.9 2.6 4.8e-22 77.5 1.3 2.2 2 0 0 2 2 2 1 POPLD (NUC188) domain MFS_1 PF07690.11 EMG48630.1 - 1.2e-32 113.0 31.7 1.4e-32 112.8 19.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMG48630.1 - 0.059 11.7 22.9 0.37 9.1 14.3 3.1 1 1 0 1 1 1 0 MFS/sugar transport protein DUF308 PF03729.8 EMG48630.1 - 3.8 7.5 27.6 0.13 12.3 3.2 4.4 3 1 1 4 4 4 0 Short repeat of unknown function (DUF308) MFS_1 PF07690.11 EMG48631.1 - 5.7e-28 97.6 14.6 5.7e-28 97.6 10.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EMG48631.1 - 6.7e-06 24.8 2.4 1.2e-05 23.9 1.7 1.5 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like Pkinase PF00069.20 EMG48632.1 - 1.8e-47 161.6 0.0 1.1e-46 159.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG48632.1 - 2.7e-23 82.3 0.0 1.4e-22 79.9 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase VIT PF08487.5 EMG48632.1 - 0.0034 17.0 0.1 0.008 15.8 0.0 1.6 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain GATase_5 PF13507.1 EMG48632.1 - 0.0054 15.6 0.1 0.0095 14.8 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain MRG PF05712.8 EMG48632.1 - 0.058 12.2 0.2 0.51 9.1 0.1 2.0 2 0 0 2 2 2 0 MRG ADH_zinc_N PF00107.21 EMG48633.1 - 6.9e-12 45.0 0.0 1.2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMG48633.1 - 2.1e-09 37.1 0.0 3.8e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain RRN7 PF11781.3 EMG48634.1 - 0.13 11.7 0.1 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-CCCH PF00642.19 EMG48635.1 - 0.00016 21.2 0.9 0.00016 21.2 0.6 4.8 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EMG48635.1 - 0.02 14.8 1.3 0.02 14.8 0.9 5.1 6 0 0 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type ANAPC15 PF15243.1 EMG48635.1 - 1.4 9.0 10.7 3.6 7.7 7.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 ADH_zinc_N PF00107.21 EMG48636.1 - 7.3e-14 51.4 0.1 2.5e-13 49.7 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMG48636.1 - 2.8e-08 33.4 0.7 2.4e-07 30.4 0.3 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain CAF1 PF04857.15 EMG48636.1 - 0.053 12.8 0.0 0.28 10.4 0.0 1.9 2 0 0 2 2 2 0 CAF1 family ribonuclease tRNA-synt_1 PF00133.17 EMG48637.1 - 6.1e-159 529.8 5.3 8.3e-159 529.3 3.7 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EMG48637.1 - 9.4e-27 93.6 0.4 2e-26 92.5 0.3 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EMG48637.1 - 1.1e-20 73.7 0.9 2.1e-11 43.1 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EMG48637.1 - 6.4e-05 22.3 0.0 0.00014 21.2 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EMG48637.1 - 0.00026 20.2 0.0 0.025 13.6 0.0 2.6 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EMG48637.1 - 0.00032 19.4 0.3 0.019 13.6 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (K) zf-FPG_IleRS PF06827.9 EMG48637.1 - 0.0015 18.1 6.8 0.0032 17.0 4.7 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS Ku PF02735.11 EMG48638.1 - 1.2e-16 60.7 0.0 2.7e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain VWA_2 PF13519.1 EMG48638.1 - 1.4e-11 44.8 0.0 2.1e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EMG48638.1 - 3.2e-07 30.2 2.0 8.2e-07 28.9 1.4 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Ku_N PF03731.10 EMG48638.1 - 6.6e-07 28.9 1.4 4.8e-06 26.1 1.0 2.3 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain MMR_HSR1 PF01926.18 EMG48639.1 - 1e-11 44.8 0.2 2.9e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMG48639.1 - 6.2e-05 22.3 0.1 0.0003 20.1 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B IIGP PF05049.8 EMG48639.1 - 0.0018 17.1 0.0 0.0026 16.6 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) DUF258 PF03193.11 EMG48639.1 - 0.0019 17.4 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EMG48639.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 AIG1 family BCDHK_Adom3 PF10436.4 EMG48639.1 - 0.13 11.7 0.0 0.29 10.6 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase KTI12 PF08433.5 EMG48640.1 - 1.4e-88 296.6 0.1 1.6e-88 296.4 0.1 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 EMG48640.1 - 2.4e-05 24.6 0.2 8.2e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EMG48640.1 - 0.00017 21.4 0.0 0.00068 19.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 EMG48640.1 - 0.022 14.4 0.1 0.067 12.8 0.0 1.8 1 1 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.1 EMG48640.1 - 0.026 15.3 0.0 0.048 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMG48640.1 - 0.029 14.5 0.1 0.13 12.4 0.0 2.1 2 1 1 3 3 3 0 RNA helicase Utp11 PF03998.8 EMG48641.1 - 1.7e-70 237.6 33.2 1.9e-70 237.4 23.0 1.0 1 0 0 1 1 1 1 Utp11 protein Big_1 PF02369.11 EMG48641.1 - 0.078 12.8 0.1 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) Oligomerisation PF02410.10 EMG48642.1 - 2.1e-14 53.3 0.0 6.5e-14 51.7 0.0 1.9 2 0 0 2 2 2 1 Oligomerisation domain Drc1-Sld2 PF11719.3 EMG48643.1 - 1.6e-58 198.8 40.2 2.7e-57 194.8 27.9 2.3 1 1 0 1 1 1 1 DNA replication and checkpoint protein SPT6_acidic PF14632.1 EMG48643.1 - 0.78 9.9 16.2 0.16 12.1 2.9 2.6 2 0 0 2 2 2 0 Acidic N-terminal SPT6 zf-C2HC5 PF06221.8 EMG48644.1 - 2.3e-23 81.6 4.9 4.2e-23 80.8 3.4 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type MFS_1 PF07690.11 EMG48646.1 - 1.5e-26 92.9 13.8 1.5e-26 92.9 9.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EMG48646.1 - 4.3e-06 25.4 2.5 7.4e-06 24.7 1.8 1.5 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like DUF308 PF03729.8 EMG48646.1 - 0.056 13.4 18.3 0.24 11.4 1.9 4.1 3 1 1 4 4 4 0 Short repeat of unknown function (DUF308) DcpS_C PF11969.3 EMG48647.1 - 6.8e-22 77.8 4.5 1.3e-21 76.9 3.1 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EMG48647.1 - 7.9e-17 61.5 1.8 2.2e-16 60.1 1.3 1.8 1 1 0 1 1 1 1 HIT domain zf-H2C2_2 PF13465.1 EMG48647.1 - 0.0046 17.1 0.6 0.016 15.4 0.4 2.0 1 0 0 1 1 1 1 Zinc-finger double domain DDE_Tnp_IS1595 PF12762.2 EMG48647.1 - 0.086 12.6 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 ISXO2-like transposase domain Pkr1 PF08636.5 EMG48648.1 - 7.4e-33 112.4 9.1 9.2e-33 112.1 6.3 1.1 1 0 0 1 1 1 1 ER protein Pkr1 O-antigen_lig PF13425.1 EMG48648.1 - 0.0017 18.3 0.1 0.0019 18.1 0.1 1.1 1 0 0 1 1 1 1 O-antigen ligase like membrane protein DUF1189 PF06691.6 EMG48648.1 - 0.0054 16.0 1.0 0.0063 15.8 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1189) DUF4131 PF13567.1 EMG48648.1 - 0.0059 16.0 0.0 0.0062 15.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) Papilloma_E5A PF05776.7 EMG48648.1 - 0.033 14.3 4.2 0.046 13.8 2.9 1.2 1 0 0 1 1 1 0 Papillomavirus E5A protein YfhO PF09586.5 EMG48648.1 - 0.035 12.1 0.3 0.039 11.9 0.2 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO LMF1 PF06762.9 EMG48648.1 - 0.062 12.0 0.3 0.066 11.9 0.2 1.0 1 0 0 1 1 1 0 Lipase maturation factor DGF-1_4 PF11024.3 EMG48648.1 - 0.44 10.9 5.4 0.14 12.5 0.9 1.9 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 zf-RING_4 PF14570.1 EMG48649.1 - 2e-19 68.9 9.9 4e-19 67.9 6.8 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_5 PF13893.1 EMG48649.1 - 5.3e-08 32.5 0.0 1.5e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMG48649.1 - 3e-07 29.9 0.0 2.8e-06 26.8 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 EMG48649.1 - 6.5e-05 22.6 2.4 0.00019 21.2 1.7 1.7 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) RRM_6 PF14259.1 EMG48649.1 - 0.00047 20.0 0.0 0.0021 17.9 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 EMG48649.1 - 0.0068 16.0 4.6 0.0068 16.0 3.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMG48649.1 - 0.022 14.4 6.9 0.055 13.1 4.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMG48649.1 - 0.058 13.2 5.3 0.13 12.0 3.6 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 EMG48649.1 - 0.78 9.8 6.9 1.7 8.7 4.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Lipase_GDSL PF00657.17 EMG48650.1 - 0.0099 15.7 0.1 0.014 15.1 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase HalX PF08663.5 EMG48650.1 - 0.014 15.3 0.2 19 5.2 0.1 3.4 3 0 0 3 3 3 0 HalX domain RusA PF05866.6 EMG48650.1 - 0.057 13.8 1.2 0.22 11.8 0.8 1.9 2 0 0 2 2 2 0 Endodeoxyribonuclease RusA NlpE PF04170.7 EMG48650.1 - 0.13 12.7 0.5 3.3 8.1 0.1 2.4 2 0 0 2 2 2 0 NlpE N-terminal domain Bromo_TP PF07524.8 EMG48651.1 - 9.2e-08 31.7 0.0 1.7e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated Yqai PF09466.5 EMG48651.1 - 0.21 11.6 5.2 4.6 7.3 0.6 2.6 2 0 0 2 2 2 0 Hypothetical protein Yqai Citrate_synt PF00285.16 EMG48653.1 - 9.6e-101 337.0 0.0 1.2e-100 336.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Exo5 PF09810.4 EMG48654.1 - 3.7e-31 108.5 0.0 3.3e-18 66.0 0.0 2.7 2 1 0 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 EMG48654.1 - 0.00015 21.2 0.1 0.011 15.1 0.1 2.5 2 1 0 2 2 2 2 PD-(D/E)XK nuclease superfamily LRR_8 PF13855.1 EMG48655.1 - 3.6e-15 55.4 14.9 2.2e-08 33.7 1.0 6.2 4 1 4 8 8 8 4 Leucine rich repeat FNIP PF05725.7 EMG48655.1 - 7.8e-09 35.3 0.7 3.7 7.5 0.1 8.4 8 4 0 8 8 8 2 FNIP Repeat LRR_4 PF12799.2 EMG48655.1 - 8.1e-09 34.9 25.0 0.0049 16.4 1.9 7.6 7 1 1 8 8 8 4 Leucine Rich repeats (2 copies) Luteo_P1-P2 PF08467.5 EMG48655.1 - 0.024 13.4 0.8 0.047 12.4 0.0 1.8 3 0 0 3 3 3 0 Luteovirus RNA polymerase P1-P2/replicase LRR_1 PF00560.28 EMG48655.1 - 0.031 14.2 20.8 0.11 12.5 0.7 7.7 7 1 0 7 7 7 0 Leucine Rich Repeat LRR_7 PF13504.1 EMG48655.1 - 0.16 12.2 16.3 3.8 8.1 0.1 9.1 11 0 0 11 11 11 0 Leucine rich repeat DUF1399 PF07173.7 EMG48656.1 - 1.1e-25 90.4 0.1 1.4e-23 83.6 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) DUF1399 PF07173.7 EMG48657.1 - 1.2e-23 83.8 5.7 5.4e-22 78.5 0.7 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF1399) SMC_N PF02463.14 EMG48658.1 - 7.1e-51 172.5 53.6 2.8e-49 167.3 37.2 3.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EMG48658.1 - 1e-26 93.2 1.1 4.5e-26 91.1 0.0 2.8 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EMG48658.1 - 1.2e-09 38.7 31.8 1.2e-09 38.7 22.0 7.1 3 2 1 5 5 5 2 AAA domain AAA_21 PF13304.1 EMG48658.1 - 7.7e-08 32.6 26.3 2.9e-06 27.4 4.1 5.3 2 2 2 4 4 4 2 AAA domain AAA_29 PF13555.1 EMG48658.1 - 1.2e-07 31.0 0.2 3.6e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EMG48658.1 - 0.4 9.8 32.5 0.012 14.8 4.5 4.7 3 1 1 4 4 4 0 Reovirus sigma C capsid protein DSPc PF00782.15 EMG48659.1 - 2.3e-28 98.3 0.1 8.6e-28 96.5 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMG48659.1 - 0.00081 18.7 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 EMG48659.1 - 0.01 14.7 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase zf-FPG_IleRS PF06827.9 EMG48659.1 - 0.026 14.1 0.8 4.3 7.0 0.1 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS PHD PF00628.24 EMG48659.1 - 0.069 12.8 2.3 4.8 6.9 0.2 2.6 2 0 0 2 2 2 0 PHD-finger PqqD PF05402.7 EMG48659.1 - 0.13 12.3 0.1 0.55 10.2 0.0 2.0 3 0 0 3 3 3 0 Coenzyme PQQ synthesis protein D (PqqD) Yippee-Mis18 PF03226.9 EMG48659.1 - 0.27 11.2 2.0 0.82 9.7 0.5 2.3 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn_Tnp_IS1595 PF12760.2 EMG48659.1 - 0.72 9.7 7.1 9.1 6.1 0.3 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF2392 PF10288.4 EMG48660.1 - 3.9e-31 107.5 0.4 1.1e-30 106.1 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) Apc15p PF05841.6 EMG48660.1 - 5.9e-18 65.7 0.6 1.6e-17 64.3 0.4 1.9 1 0 0 1 1 1 1 Apc15p protein ATP_bind_3 PF01171.15 EMG48660.1 - 6.6e-06 25.7 0.0 0.033 13.6 0.0 2.4 1 1 0 1 1 1 1 PP-loop family Racemase_4 PF13615.1 EMG48660.1 - 0.019 15.2 1.1 0.89 9.8 0.5 2.7 2 1 0 2 2 2 0 Putative alanine racemase Mitofilin PF09731.4 EMG48661.1 - 1.9e-130 436.2 36.1 2.4e-129 432.6 25.1 2.2 1 1 0 1 1 1 1 Mitochondrial inner membrane protein YebG PF07130.7 EMG48661.1 - 0.94 9.2 4.7 0.82 9.4 1.4 2.4 2 0 0 2 2 2 0 YebG protein DUF4407 PF14362.1 EMG48661.1 - 3 6.7 11.4 3.2 6.6 6.4 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Endotoxin_N PF03945.9 EMG48661.1 - 3.1 7.1 12.4 1.6 8.0 0.5 2.6 2 1 1 3 3 3 0 delta endotoxin, N-terminal domain WD40 PF00400.27 EMG48662.1 - 1.1e-43 145.5 13.8 1.8e-06 27.5 0.0 9.8 10 0 0 10 10 10 9 WD domain, G-beta repeat PD40 PF07676.7 EMG48662.1 - 0.012 15.2 4.2 5 6.8 0.2 5.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Lactonase PF10282.4 EMG48662.1 - 0.022 13.8 0.0 0.14 11.2 0.0 2.3 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Cyt-b5 PF00173.23 EMG48664.1 - 1.1e-11 44.3 0.0 1.5e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acetyltransf_1 PF00583.19 EMG48665.1 - 4.8e-16 58.5 0.0 6.9e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMG48665.1 - 3.8e-11 42.9 0.1 5.4e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMG48665.1 - 5.2e-07 29.7 0.9 1.1e-06 28.6 0.6 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMG48665.1 - 1.6e-05 24.9 0.0 1.9e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMG48665.1 - 7e-05 22.5 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EMG48665.1 - 0.00037 20.4 0.0 0.00039 20.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMG48665.1 - 0.044 13.9 0.0 0.11 12.6 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMG48665.1 - 0.093 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DnaJ PF00226.26 EMG48666.1 - 5.1e-18 64.5 1.6 5.1e-18 64.5 1.1 2.4 2 0 0 2 2 2 1 DnaJ domain Sec63 PF02889.11 EMG48666.1 - 2.1e-14 53.4 0.1 8.6e-14 51.4 0.1 1.7 1 1 1 2 2 2 1 Sec63 Brl domain AICARFT_IMPCHas PF01808.13 EMG48667.1 - 6.1e-117 390.1 0.0 8e-117 389.8 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EMG48667.1 - 3.3e-24 84.6 0.0 9.1e-24 83.2 0.0 1.8 1 0 0 1 1 1 1 MGS-like domain DUF3664 PF12406.3 EMG48667.1 - 0.021 15.3 0.2 0.056 14.0 0.1 1.6 1 0 0 1 1 1 0 Surface protein Ribosomal_L15e PF00827.12 EMG48668.1 - 2.6e-91 304.3 13.8 3e-91 304.1 9.5 1.0 1 0 0 1 1 1 1 Ribosomal L15 AAA PF00004.24 EMG48669.1 - 8.8e-43 145.6 0.0 1.5e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMG48669.1 - 7.2e-07 29.3 0.1 3e-05 24.0 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EMG48669.1 - 1.4e-06 28.0 0.1 2.2e-05 24.2 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EMG48669.1 - 2.8e-06 27.3 0.0 5.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EMG48669.1 - 2.1e-05 24.6 0.1 0.0029 17.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMG48669.1 - 7.2e-05 21.9 0.0 0.00014 21.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EMG48669.1 - 0.00012 21.7 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EMG48669.1 - 0.00021 22.0 0.7 0.001 19.8 0.1 2.5 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EMG48669.1 - 0.0004 20.0 0.0 0.00075 19.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 EMG48669.1 - 0.0023 16.7 0.0 0.0039 15.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 EMG48669.1 - 0.0025 17.9 0.0 0.0058 16.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.12 EMG48669.1 - 0.0029 17.0 0.1 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 EMG48669.1 - 0.0046 16.3 0.7 0.031 13.6 0.3 2.2 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EMG48669.1 - 0.0047 16.1 0.1 0.0098 15.0 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EMG48669.1 - 0.006 16.4 0.0 0.015 15.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EMG48669.1 - 0.0068 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EMG48669.1 - 0.0081 16.1 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMG48669.1 - 0.011 16.0 0.4 0.087 13.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EMG48669.1 - 0.012 15.2 0.4 0.024 14.2 0.3 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EMG48669.1 - 0.015 14.4 0.2 0.098 11.7 0.0 2.3 2 0 0 2 2 2 0 KaiC DUF4200 PF13863.1 EMG48669.1 - 0.025 14.5 0.3 0.062 13.2 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) PhoH PF02562.11 EMG48669.1 - 0.036 13.3 0.1 0.065 12.4 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.7 EMG48669.1 - 0.055 12.5 0.1 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.12 EMG48669.1 - 0.072 11.9 0.1 0.13 11.0 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 EMG48669.1 - 0.073 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EMG48669.1 - 0.094 12.2 0.3 0.83 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EMG48669.1 - 0.1 12.2 0.1 0.29 10.7 0.0 1.8 1 1 1 2 2 2 0 NACHT domain AAA_23 PF13476.1 EMG48669.1 - 0.1 12.9 1.8 7.3 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EMG48669.1 - 0.11 11.9 0.1 0.41 10.0 0.1 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain KOW PF00467.24 EMG48670.1 - 0.00054 19.5 0.0 0.0016 18.0 0.0 1.8 1 0 0 1 1 1 1 KOW motif EF-hand_7 PF13499.1 EMG48671.1 - 2.2e-21 75.7 10.8 3.4e-11 43.1 1.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EMG48671.1 - 8.7e-20 68.4 13.1 7.8e-08 31.0 0.1 4.9 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 EMG48671.1 - 1.2e-16 60.0 12.9 2.4e-08 33.4 1.0 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EMG48671.1 - 2.4e-16 58.0 8.8 2.7e-07 29.8 0.1 4.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 EMG48671.1 - 6.2e-14 50.5 5.8 5.2e-05 22.3 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.2 EMG48671.1 - 5e-06 26.1 3.7 0.00013 21.6 0.1 2.7 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EMG48671.1 - 0.0022 17.8 0.3 0.025 14.4 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain FIVAR PF07554.8 EMG48671.1 - 0.021 15.0 2.7 0.044 14.0 1.9 1.6 1 0 0 1 1 1 0 Uncharacterised Sugar-binding Domain H-kinase_dim PF02895.9 EMG48671.1 - 0.036 14.4 0.3 0.12 12.7 0.0 2.0 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain VCBS PF13517.1 EMG48671.1 - 0.71 10.2 4.4 0.78 10.1 0.1 2.8 2 2 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella CAP_GLY PF01302.20 EMG48672.1 - 6.7e-20 70.5 0.7 1.1e-19 69.8 0.5 1.4 1 0 0 1 1 1 1 CAP-Gly domain MbeD_MobD PF04899.7 EMG48672.1 - 0.057 13.3 8.0 0.2 11.5 0.2 4.3 3 1 0 3 3 3 0 MbeD/MobD like TraF_2 PF13729.1 EMG48672.1 - 3.1 6.5 10.3 2.9 6.6 0.8 3.6 3 2 1 5 5 5 0 F plasmid transfer operon, TraF, protein PIGA PF08288.7 EMG48673.1 - 1.1e-44 150.6 0.5 3.2e-44 149.2 0.3 1.8 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EMG48673.1 - 2.3e-34 118.2 0.1 3.2e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EMG48673.1 - 1.2e-15 57.6 0.1 2.6e-15 56.5 0.1 1.6 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EMG48673.1 - 6.8e-15 55.4 0.0 1.6e-14 54.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EMG48673.1 - 1.5e-11 44.7 0.0 2.2e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 EMG48673.1 - 0.002 17.9 0.1 0.0035 17.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 EMG48673.1 - 0.0028 17.8 0.0 0.0053 16.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 MFS_1 PF07690.11 EMG48674.1 - 2.2e-49 168.0 24.3 5.4e-41 140.4 11.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG48674.1 - 1e-10 40.8 27.7 2.3e-08 33.0 7.9 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter PIRT PF15099.1 EMG48674.1 - 0.023 13.8 0.1 0.91 8.7 0.0 2.4 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family LRR_4 PF12799.2 EMG48675.1 - 1.3e-06 27.8 11.0 1.5e-06 27.6 0.6 3.8 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG48675.1 - 0.0042 16.8 8.6 0.0043 16.7 3.0 2.8 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 EMG48675.1 - 0.0047 16.7 6.2 3.7 7.9 0.1 4.5 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_9 PF14580.1 EMG48675.1 - 0.005 16.4 0.5 0.0088 15.6 0.4 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_7 PF13504.1 EMG48675.1 - 1.7 9.1 6.5 49 4.7 0.1 4.3 4 0 0 4 4 4 0 Leucine rich repeat MCM PF00493.18 EMG48677.1 - 8.3e-138 458.7 0.8 1.3e-137 458.0 0.6 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EMG48677.1 - 1.1e-35 122.9 37.0 1.1e-35 122.9 25.6 3.5 4 0 0 4 4 4 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EMG48677.1 - 3.2e-16 59.9 0.1 1.1e-15 58.2 0.1 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EMG48677.1 - 3.9e-08 32.7 0.0 5.5e-06 25.6 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EMG48677.1 - 7.6e-08 32.1 1.2 5.1e-06 26.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EMG48677.1 - 0.0019 17.8 0.0 0.038 13.6 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EMG48677.1 - 0.0021 17.5 0.1 0.013 14.9 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain ApoO PF09769.4 EMG48677.1 - 0.13 11.9 0.4 0.26 10.9 0.3 1.4 1 0 0 1 1 1 0 Apolipoprotein O Longin PF13774.1 EMG48678.1 - 2e-24 84.9 0.3 3.4e-24 84.2 0.2 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EMG48678.1 - 1.3e-15 56.6 0.3 2.5e-15 55.8 0.2 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 EMG48678.1 - 0.0048 16.6 0.4 0.0072 16.1 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF3932 PF13068.1 EMG48678.1 - 0.0069 16.4 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3932) DUF4588 PF15251.1 EMG48679.1 - 3.9e-35 121.9 15.6 2e-33 116.3 10.8 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) DUF650 PF04894.7 EMG48679.1 - 0.046 13.2 1.3 0.13 11.7 0.1 2.0 2 1 1 3 3 3 0 Archaeal protein of unknown function (DUF650) Hexapep PF00132.19 EMG48680.1 - 7.5e-09 34.7 6.5 0.00047 19.5 0.5 3.7 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EMG48680.1 - 2.1e-05 24.6 0.0 4.1e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 EMG48680.1 - 0.0001 21.7 0.0 0.00017 20.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase CTP_transf_3 PF02348.14 EMG48680.1 - 0.00013 21.7 0.0 0.00035 20.2 0.0 1.7 1 0 0 1 1 1 1 Cytidylyltransferase Hexapep_2 PF14602.1 EMG48680.1 - 0.26 10.8 8.8 0.99 9.0 0.7 3.3 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase TPR_16 PF13432.1 EMG48681.1 - 0.0022 18.5 0.7 0.067 13.8 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMG48681.1 - 0.0024 17.7 9.1 0.25 11.2 0.0 3.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMG48681.1 - 0.0076 15.8 1.5 4.8 6.8 0.5 2.9 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EMG48681.1 - 0.056 13.3 9.2 1.4 9.0 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMG48681.1 - 0.1 12.2 9.9 1.3 8.7 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMG48681.1 - 0.16 12.7 1.1 27 5.7 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Sugar_tr PF00083.19 EMG48682.1 - 3.4e-82 276.4 14.2 4e-82 276.1 9.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG48682.1 - 2e-26 92.5 27.1 7.2e-18 64.4 0.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TB2_DP1_HVA22 PF03134.14 EMG48682.1 - 0.035 13.8 1.1 0.11 12.2 0.8 1.8 1 0 0 1 1 1 0 TB2/DP1, HVA22 family Brr6_like_C_C PF10104.4 EMG48683.1 - 1.3e-42 144.4 7.0 2.5e-42 143.6 4.9 1.4 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain MFS_1 PF07690.11 EMG48684.1 - 5e-28 97.8 38.9 5e-28 97.8 27.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TFIID_20kDa PF03847.8 EMG48685.1 - 1.8e-17 63.3 0.0 3.8e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A eIF3_subunit PF08597.5 EMG48685.1 - 4.8 6.6 24.1 0.078 12.5 7.3 2.9 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Pkinase PF00069.20 EMG48686.1 - 7.5e-61 205.5 0.0 2.2e-60 204.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG48686.1 - 2.7e-35 121.7 0.0 4.2e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EMG48686.1 - 0.0067 15.7 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Med25_SD1 PF11235.3 EMG48686.1 - 0.021 15.1 8.2 0.048 13.9 5.7 1.5 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 zinc_ribbon_2 PF13240.1 EMG48687.1 - 0.0059 16.0 0.8 0.0059 16.0 0.5 4.1 6 0 0 6 6 6 1 zinc-ribbon domain HypA PF01155.14 EMG48687.1 - 0.026 14.2 1.5 0.026 14.2 1.1 3.6 2 2 1 3 3 3 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EMG48687.1 - 0.24 11.2 32.3 1.7 8.5 6.9 4.7 1 1 4 5 5 5 0 Double zinc ribbon zf-CHY PF05495.7 EMG48687.1 - 1.1 9.4 26.3 5.4 7.2 2.4 4.7 3 1 0 3 3 3 0 CHY zinc finger zinc-ribbons_6 PF07191.7 EMG48687.1 - 5.1 6.9 24.8 1.6 8.5 5.3 4.4 3 1 1 4 4 4 0 zinc-ribbons TPR_14 PF13428.1 EMG48689.1 - 0.00073 19.9 0.0 1.1 10.1 0.0 4.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMG48689.1 - 0.00088 19.0 1.4 5.1 7.2 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMG48689.1 - 0.0013 19.3 0.0 0.17 12.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMG48689.1 - 0.0025 18.1 0.2 0.15 12.4 0.1 3.1 3 1 1 4 4 4 2 Tetratricopeptide repeat NRDE-2 PF08424.5 EMG48689.1 - 0.017 13.9 3.8 0.019 13.8 0.5 2.4 3 0 0 3 3 3 0 NRDE-2, necessary for RNA interference TPR_11 PF13414.1 EMG48689.1 - 0.03 13.9 0.9 2.8 7.6 0.2 2.8 2 1 0 2 2 2 0 TPR repeat TPR_8 PF13181.1 EMG48689.1 - 0.56 10.1 11.0 0.81 9.6 0.1 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat Methyltransf_16 PF10294.4 EMG48690.1 - 6.5e-13 48.4 0.0 1.1e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EMG48690.1 - 1.2e-06 29.0 0.0 2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMG48690.1 - 0.00067 19.4 0.0 0.0013 18.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMG48690.1 - 0.0017 18.8 0.1 0.01 16.2 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMG48690.1 - 0.0072 15.9 0.0 0.021 14.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMG48690.1 - 0.031 14.7 0.0 0.056 13.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF202 PF02656.10 EMG48691.1 - 2.3e-26 91.8 0.1 2.3e-26 91.8 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SdpI PF13630.1 EMG48691.1 - 1 9.1 8.0 0.86 9.3 3.6 2.0 2 0 0 2 2 2 0 SdpI/YhfL protein family NfeD PF01957.13 EMG48691.1 - 1.3 9.1 6.0 0.59 10.2 2.6 1.5 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF3784 PF12650.2 EMG48691.1 - 2.6 8.0 7.4 0.58 10.1 2.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) Metallophos PF00149.23 EMG48693.1 - 7.7e-40 136.4 0.4 9.4e-40 136.1 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMG48693.1 - 0.096 12.5 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Mon1 PF03164.9 EMG48694.1 - 6.7e-69 232.4 10.4 9.6e-69 231.9 7.2 1.2 1 0 0 1 1 1 1 Trafficking protein Mon1 BRCA-2_OB3 PF09104.5 EMG48694.1 - 0.019 14.7 0.1 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 IPPT PF01715.12 EMG48694.1 - 0.049 12.6 0.0 0.084 11.8 0.0 1.3 1 0 0 1 1 1 0 IPP transferase RRF PF01765.14 EMG48695.1 - 4.4e-35 120.5 1.7 4.4e-35 120.5 1.2 1.5 2 0 0 2 2 2 1 Ribosome recycling factor Spore_III_AB PF09548.5 EMG48695.1 - 0.0013 18.5 0.6 0.009 15.7 0.4 2.0 2 0 0 2 2 2 1 Stage III sporulation protein AB (spore_III_AB) WAC_Acf1_DNA_bd PF10537.4 EMG48695.1 - 0.038 14.1 0.8 0.9 9.7 0.2 2.6 2 1 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal DAGAT PF03982.8 EMG48695.1 - 0.13 10.9 1.3 1.8 7.1 0.2 2.2 2 0 0 2 2 2 0 Diacylglycerol acyltransferase Ipi1_N PF12333.3 EMG48696.1 - 1.5e-25 89.1 1.7 1.5e-25 89.1 1.2 2.0 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Transaldolase PF00923.14 EMG48697.1 - 1.7e-97 325.9 1.5 2e-97 325.8 1.0 1.0 1 0 0 1 1 1 1 Transaldolase Flavokinase PF01687.12 EMG48698.1 - 2.9e-39 133.8 0.0 3.5e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase GSCFA PF08885.6 EMG48698.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 GSCFA family Peptidase_M24 PF00557.19 EMG48700.1 - 7.6e-18 64.8 0.0 9.7e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF1769 PF08588.5 EMG48702.1 - 2.8e-25 88.0 0.7 7.4e-25 86.6 0.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Clat_adaptor_s PF01217.15 EMG48703.1 - 3.3e-16 59.2 3.0 9e-16 57.8 2.1 1.6 1 1 0 1 1 1 1 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.1 EMG48703.1 - 0.17 11.8 2.5 0.41 10.5 0.4 2.1 1 1 1 2 2 2 0 AP-5 complex subunit sigma-1 VTC PF09359.5 EMG48704.1 - 3.9e-57 193.4 9.7 1.8e-56 191.2 6.8 2.0 1 1 0 1 1 1 1 VTC domain SPX PF03105.14 EMG48704.1 - 1e-12 48.4 45.1 9.7e-06 25.5 0.7 5.1 2 2 4 6 6 6 3 SPX domain DUF202 PF02656.10 EMG48704.1 - 1e-07 32.0 2.4 2.1e-07 31.0 1.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) H_lectin PF09458.5 EMG48704.1 - 0.0022 17.6 0.2 0.0052 16.4 0.1 1.6 1 0 0 1 1 1 1 H-type lectin domain Osteopontin PF00865.13 EMG48704.1 - 0.031 13.5 20.1 0.19 10.9 2.9 2.4 2 0 0 2 2 2 0 Osteopontin AF1Q PF15017.1 EMG48704.1 - 4.5 7.2 16.7 0.57 10.1 3.9 2.9 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Inhibitor_I53 PF11714.3 EMG48704.1 - 6.6 6.7 7.9 2.3 8.2 0.8 2.4 2 0 0 2 2 2 0 Thrombin inhibitor Madanin Peptidase_C48 PF02902.14 EMG48705.1 - 1.1e-30 106.8 0.4 1.8e-30 106.2 0.1 1.5 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain RNA12 PF10443.4 EMG48706.1 - 9e-147 489.0 1.7 1.9e-145 484.6 0.3 2.7 2 1 0 2 2 2 1 RNA12 protein RRM_1 PF00076.17 EMG48706.1 - 0.0013 18.3 0.0 0.0081 15.7 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG48706.1 - 0.01 15.6 0.0 0.056 13.2 0.0 2.3 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.24 EMG48707.1 - 1.3e-38 132.1 0.0 4.3e-38 130.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMG48707.1 - 3.2e-07 30.4 0.3 0.00077 19.4 0.0 2.9 3 1 1 4 4 4 2 AAA ATPase domain AAA_14 PF13173.1 EMG48707.1 - 9.6e-07 28.7 0.1 1.1e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EMG48707.1 - 1.7e-06 28.2 0.5 0.0019 18.3 0.2 3.2 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EMG48707.1 - 2.6e-06 26.6 0.0 1.7e-05 24.0 0.0 2.1 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EMG48707.1 - 1.8e-05 25.5 0.0 6.9e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EMG48707.1 - 5.8e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EMG48707.1 - 0.00011 21.9 0.2 0.0031 17.2 0.1 2.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EMG48707.1 - 0.00016 21.5 0.0 0.00027 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EMG48707.1 - 0.00051 19.4 0.0 0.0015 17.9 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.13 EMG48707.1 - 0.00077 19.1 0.1 0.003 17.2 0.0 2.0 2 1 0 2 2 2 1 Bacterial dnaA protein Zeta_toxin PF06414.7 EMG48707.1 - 0.00098 18.2 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 EMG48707.1 - 0.001 18.5 0.4 0.072 12.4 0.1 2.5 1 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EMG48707.1 - 0.001 19.1 0.0 0.0025 17.9 0.0 1.9 1 1 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.16 EMG48707.1 - 0.0011 18.2 0.1 0.0024 17.0 0.0 1.5 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EMG48707.1 - 0.0018 17.9 0.1 0.022 14.4 0.1 2.2 2 0 0 2 2 2 1 NACHT domain Sigma54_activ_2 PF14532.1 EMG48707.1 - 0.0021 18.1 0.0 0.0042 17.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EMG48707.1 - 0.0027 16.6 0.0 0.0045 15.9 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_18 PF13238.1 EMG48707.1 - 0.0029 17.9 0.0 0.012 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EMG48707.1 - 0.0031 16.4 0.0 0.055 12.3 0.0 2.4 2 1 0 2 2 2 1 NB-ARC domain Arch_ATPase PF01637.13 EMG48707.1 - 0.0032 17.2 2.0 0.16 11.6 0.0 3.1 1 1 2 3 3 3 1 Archaeal ATPase TIP49 PF06068.8 EMG48707.1 - 0.0042 15.8 0.0 0.0074 15.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus DUF815 PF05673.8 EMG48707.1 - 0.0082 15.0 0.0 0.016 14.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 EMG48707.1 - 0.011 15.3 0.1 0.023 14.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EMG48707.1 - 0.019 14.4 0.0 0.081 12.3 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 EMG48707.1 - 0.024 14.5 0.0 0.069 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EMG48707.1 - 0.025 14.9 2.3 0.13 12.5 0.1 2.5 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.10 EMG48707.1 - 0.026 13.1 0.1 0.2 10.2 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein ABC_tran PF00005.22 EMG48707.1 - 0.027 14.7 0.0 0.066 13.5 0.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 EMG48707.1 - 0.029 13.7 0.5 0.65 9.3 0.0 2.7 2 1 1 3 3 3 0 AAA-like domain Viral_helicase1 PF01443.13 EMG48707.1 - 0.055 12.9 0.0 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EMG48707.1 - 0.06 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain SMC_N PF02463.14 EMG48707.1 - 0.12 11.6 0.2 5.6 6.1 0.1 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain Sugar_tr PF00083.19 EMG48708.1 - 1.1e-80 271.4 25.5 1.5e-80 271.0 17.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG48708.1 - 4.2e-27 94.7 29.7 4.2e-27 94.7 20.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily tRNA_U5-meth_tr PF05958.6 EMG48709.1 - 8.2e-21 74.0 0.5 5.1e-20 71.4 0.1 2.0 1 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EMG48709.1 - 2.2e-10 40.3 1.0 1.2e-09 37.9 0.1 2.5 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 EMG48709.1 - 3.8e-10 39.6 0.1 7.7e-10 38.6 0.1 1.6 1 0 0 1 1 1 1 Met-10+ like-protein TRAM PF01938.15 EMG48709.1 - 9.6e-07 28.5 0.1 3.1e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 TRAM domain Methyltransf_18 PF12847.2 EMG48709.1 - 1.3e-05 25.7 0.1 0.00019 22.0 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EMG48709.1 - 0.00011 21.5 0.0 0.0003 20.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EMG48709.1 - 0.00038 19.5 0.1 0.00094 18.2 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EMG48709.1 - 0.0011 18.1 0.0 0.0028 16.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EMG48709.1 - 0.0031 16.6 0.2 0.0094 15.0 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EMG48709.1 - 0.0037 17.2 0.0 0.0072 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TRM PF02005.11 EMG48709.1 - 0.016 14.1 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase PCMT PF01135.14 EMG48709.1 - 0.024 14.1 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MA3 PF02847.12 EMG48710.1 - 5.8e-24 83.9 0.0 3e-22 78.4 0.0 2.9 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.14 EMG48710.1 - 1.1e-20 73.9 10.9 2.3e-19 69.6 5.7 2.8 2 1 0 2 2 2 2 MIF4G domain CAP_N PF01213.14 EMG48711.1 - 4.4e-98 328.4 3.4 6.6e-98 327.8 2.4 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EMG48711.1 - 6.9e-55 184.7 3.1 1e-54 184.1 2.1 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Actin PF00022.14 EMG48712.1 - 3.3e-50 170.6 0.0 1.2e-30 106.2 0.0 2.4 2 1 0 2 2 2 2 Actin Nol1_Nop2_Fmu PF01189.12 EMG48713.1 - 7.3e-107 356.9 0.0 1.2e-106 356.2 0.0 1.4 1 0 0 1 1 1 1 NOL1/NOP2/sun family Met_10 PF02475.11 EMG48713.1 - 0.00064 19.3 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 Met-10+ like-protein FtsJ PF01728.14 EMG48713.1 - 0.0022 18.0 0.0 0.0048 16.8 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 EMG48713.1 - 0.016 14.8 0.0 0.036 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Gcd10p PF04189.8 EMG48714.1 - 1.2e-100 336.4 3.2 1.8e-100 335.9 2.2 1.2 1 0 0 1 1 1 1 Gcd10p family Methyltransf_12 PF08242.7 EMG48714.1 - 0.038 14.4 0.0 1.1 9.8 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain S4 PF01479.20 EMG48715.1 - 2.6e-14 52.3 0.1 9.7e-14 50.5 0.0 2.1 2 0 0 2 2 2 1 S4 domain Methyltransf_26 PF13659.1 EMG48715.1 - 3.6e-13 49.5 0.0 9.4e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMG48715.1 - 3e-12 46.3 0.8 4.3e-11 42.6 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMG48715.1 - 2.1e-08 34.6 0.0 1.5e-07 31.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EMG48715.1 - 1.1e-07 31.3 0.0 3.4e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EMG48715.1 - 6.5e-06 25.4 1.1 1.7e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 EMG48715.1 - 2.4e-05 24.6 0.0 8.2e-05 22.9 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_10 PF05971.7 EMG48715.1 - 7.2e-05 22.0 0.0 0.00014 21.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Cons_hypoth95 PF03602.10 EMG48715.1 - 0.00031 20.1 0.1 0.0018 17.7 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical protein 95 ResB PF05140.9 EMG48715.1 - 0.00091 17.8 1.5 0.0017 16.9 1.0 1.5 1 1 0 1 1 1 1 ResB-like family UPF0020 PF01170.13 EMG48715.1 - 0.0026 17.3 0.0 0.0066 16.0 0.0 1.7 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 AviRa PF11599.3 EMG48715.1 - 0.0044 16.0 0.9 0.038 13.0 0.2 2.2 1 1 1 2 2 2 1 RRNA methyltransferase AviRa Methyltransf_15 PF09445.5 EMG48715.1 - 0.0064 16.0 0.0 0.016 14.7 0.0 1.7 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_12 PF08242.7 EMG48715.1 - 0.01 16.2 0.2 0.076 13.4 0.0 2.6 3 0 0 3 3 2 0 Methyltransferase domain S4_2 PF13275.1 EMG48715.1 - 0.05 13.1 0.0 0.18 11.4 0.0 1.9 1 0 0 1 1 1 0 S4 domain Methyltransf_11 PF08241.7 EMG48715.1 - 0.053 14.0 0.0 0.26 11.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain MutS_V PF00488.16 EMG48716.1 - 8.6e-78 260.9 0.0 1.6e-77 260.0 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EMG48716.1 - 8.9e-34 117.0 0.2 8.9e-34 117.0 0.1 2.6 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.15 EMG48716.1 - 3e-20 72.3 0.0 2.5e-19 69.3 0.0 2.3 2 0 0 2 2 2 1 MutS domain I Eaf7 PF07904.8 EMG48716.1 - 3.1e-15 55.9 1.4 3.1e-15 55.9 0.9 3.9 3 1 0 3 3 3 1 Chromatin modification-related protein EAF7 MutS_II PF05188.12 EMG48716.1 - 6.2e-11 42.5 0.0 6.2e-11 42.5 0.0 2.4 2 0 0 2 2 2 1 MutS domain II Gar1 PF04410.9 EMG48717.1 - 4.4e-50 169.1 3.8 4.4e-50 169.1 2.7 2.3 2 1 0 2 2 2 1 Gar1/Naf1 RNA binding region Snapin_Pallidin PF14712.1 EMG48718.1 - 0.021 15.1 0.5 0.037 14.3 0.4 1.4 1 0 0 1 1 1 0 Snapin/Pallidin Tox-MPTase2 PF15638.1 EMG48718.1 - 0.048 13.1 0.1 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 2 MFS_1 PF07690.11 EMG48719.1 - 1.8e-37 128.8 30.6 1.8e-37 128.8 21.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG48719.1 - 1.1e-07 30.8 11.3 1.1e-07 30.8 7.8 3.3 3 0 0 3 3 3 3 Sugar (and other) transporter E1-E2_ATPase PF00122.15 EMG48719.1 - 0.0071 15.4 0.6 0.0071 15.4 0.4 2.2 2 0 0 2 2 2 1 E1-E2 ATPase DnaJ PF00226.26 EMG48720.1 - 1.9e-27 94.7 3.6 3.6e-27 93.8 2.5 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EMG48720.1 - 1.4e-20 73.0 1.0 2.7e-18 65.6 0.0 3.2 3 1 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EMG48720.1 - 7e-13 48.4 20.4 1.3e-12 47.5 14.2 1.5 1 0 0 1 1 1 1 DnaJ central domain COP23 PF14218.1 EMG48720.1 - 0.0085 15.6 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Circadian oscillating protein COP23 Malate_DH PF12434.3 EMG48720.1 - 0.0099 15.5 1.0 0.025 14.2 0.7 1.7 1 0 0 1 1 1 1 Malate dehydrogenase enzyme HypA PF01155.14 EMG48720.1 - 0.011 15.4 13.2 0.11 12.1 0.7 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family NDT80_PhoG PF05224.7 EMG48721.1 - 6.6e-41 140.3 0.3 1.3e-40 139.4 0.2 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family GNAT_acetyltr_2 PF13718.1 EMG48722.1 - 1.8e-80 268.8 0.0 3.9e-80 267.8 0.0 1.6 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EMG48722.1 - 6e-67 224.6 0.0 4.2e-66 221.9 0.0 2.4 2 1 0 2 2 2 1 Helicase tRNA_bind_2 PF13725.1 EMG48722.1 - 2.7e-40 136.5 1.9 1.1e-39 134.6 1.3 2.1 1 0 0 1 1 1 1 Possible tRNA binding domain DUF1726 PF08351.6 EMG48722.1 - 2.7e-40 135.9 0.3 8.9e-40 134.2 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) Acetyltransf_7 PF13508.1 EMG48722.1 - 0.0043 17.1 0.0 0.018 15.2 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Sigma70_r4_2 PF08281.7 EMG48722.1 - 0.021 14.2 0.5 0.32 10.4 0.0 2.9 3 0 0 3 3 3 0 Sigma-70, region 4 Acetyltransf_1 PF00583.19 EMG48722.1 - 0.065 13.2 0.0 0.24 11.4 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family AAA_18 PF13238.1 EMG48723.1 - 4.3e-09 36.7 0.2 1.8e-08 34.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EMG48723.1 - 4.1e-07 29.7 0.0 8.5e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EMG48723.1 - 5.9e-07 30.3 0.2 5e-06 27.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMG48723.1 - 0.00064 18.8 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_21 PF13304.1 EMG48723.1 - 0.00075 19.5 2.7 0.00089 19.2 1.9 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMG48723.1 - 0.011 15.6 0.0 0.036 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 EMG48723.1 - 0.014 14.9 0.0 0.034 13.7 0.0 1.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_14 PF13173.1 EMG48723.1 - 0.016 15.1 0.1 0.063 13.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 EMG48723.1 - 0.02 13.6 0.0 0.023 13.3 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit KTI12 PF08433.5 EMG48723.1 - 0.097 11.8 0.1 0.13 11.3 0.1 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_22 PF13401.1 EMG48723.1 - 0.14 12.3 0.0 0.31 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain CBFD_NFYB_HMF PF00808.18 EMG48724.1 - 9.4e-28 96.0 0.2 1.2e-27 95.7 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMG48724.1 - 4.1e-07 30.0 0.0 6.5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EMG48724.1 - 0.028 14.1 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.8 EMG48724.1 - 0.031 14.5 1.4 0.18 12.1 0.1 2.4 2 1 1 3 3 3 0 Transcription initiation factor TFIID subunit A TFIID-18kDa PF02269.11 EMG48724.1 - 0.035 13.9 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Rft-1 PF04506.8 EMG48725.1 - 1.3e-98 330.7 48.5 2.3e-98 329.9 33.6 1.4 1 1 0 1 1 1 1 Rft protein Polysacc_synt PF01943.12 EMG48725.1 - 1.5e-06 27.6 25.1 1.5e-06 27.6 17.4 2.2 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein DUF4201 PF13870.1 EMG48726.1 - 0.00049 19.5 0.1 0.00049 19.5 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) zf-CCHC PF00098.18 EMG48726.1 - 0.011 15.6 1.2 0.011 15.6 0.8 1.6 2 0 0 2 2 2 0 Zinc knuckle zf-CHY PF05495.7 EMG48726.1 - 0.071 13.2 3.9 0.41 10.8 0.6 2.3 2 0 0 2 2 2 0 CHY zinc finger DUF4279 PF14106.1 EMG48726.1 - 0.085 12.7 0.1 2 8.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) zinc_ribbon_5 PF13719.1 EMG48726.1 - 0.098 12.2 3.5 1.9 8.1 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EMG48726.1 - 0.13 12.0 3.3 2.4 7.9 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-FCS PF06467.9 EMG48726.1 - 0.14 11.7 9.1 2.5 7.8 2.3 2.6 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-LITAF-like PF10601.4 EMG48726.1 - 0.17 11.7 6.3 3.6 7.5 0.8 2.4 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Kinesin-related PF06548.6 EMG48726.1 - 0.43 9.0 5.0 4.2 5.8 1.2 2.1 2 0 0 2 2 2 0 Kinesin-related DUF2296 PF10058.4 EMG48726.1 - 0.44 10.3 3.4 1.5 8.6 0.3 2.5 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) zinc-ribbons_6 PF07191.7 EMG48726.1 - 0.5 10.2 6.5 2.9 7.7 0.4 2.5 2 1 0 2 2 2 0 zinc-ribbons Tnp_zf-ribbon_2 PF13842.1 EMG48726.1 - 1.1 9.7 7.2 28 5.2 0.1 2.7 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon LSM PF01423.17 EMG48727.1 - 4.1e-17 61.4 0.2 5.6e-17 61.0 0.2 1.2 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 EMG48727.1 - 0.037 13.7 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Gem-associated protein 7 (Gemin7) PLU-1 PF08429.6 EMG48727.1 - 0.056 12.3 0.0 0.065 12.1 0.0 1.1 1 0 0 1 1 1 0 PLU-1-like protein SM-ATX PF14438.1 EMG48727.1 - 0.081 12.8 0.0 0.1 12.5 0.0 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain Peptidase_C1_2 PF03051.10 EMG48728.1 - 6e-154 512.7 6.5 7.2e-154 512.4 4.5 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EMG48728.1 - 4.5e-06 26.6 0.7 0.00067 19.5 0.1 2.8 2 1 0 2 2 2 2 Papain family cysteine protease DUF3332 PF11810.3 EMG48729.1 - 0.054 13.1 1.2 0.059 13.0 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) Ycf1 PF05758.7 EMG48729.1 - 6.8 4.2 6.2 6.1 4.4 4.3 1.0 1 0 0 1 1 1 0 Ycf1 Spore_coat_CotO PF14153.1 EMG48729.1 - 6.8 6.0 10.4 7.9 5.8 7.2 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Leu_zip PF15294.1 EMG48730.1 - 0.0017 17.5 1.4 0.0031 16.6 1.0 1.4 1 0 0 1 1 1 1 Leucine zipper DivIC PF04977.10 EMG48730.1 - 0.097 12.1 2.0 0.22 11.0 1.4 1.7 1 0 0 1 1 1 0 Septum formation initiator UAF_Rrn10 PF05234.6 EMG48731.1 - 9e-12 45.0 0.2 2.4e-11 43.7 0.2 1.7 1 1 0 1 1 1 1 UAF complex subunit Rrn10 Nucleoplasmin PF03066.10 EMG48731.1 - 0.22 11.0 8.0 0.3 10.5 5.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin TEX19 PF15553.1 EMG48731.1 - 1.1 9.0 4.2 1.8 8.3 2.9 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 CENP-B_dimeris PF09026.5 EMG48731.1 - 4 7.7 16.9 2.7 8.2 9.4 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nol1_Nop2_Fmu PF01189.12 EMG48732.1 - 6.2e-55 186.5 0.0 1.3e-40 139.5 0.0 2.5 1 1 1 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 EMG48732.1 - 0.0068 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EMG48732.1 - 0.029 14.4 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Palm_thioest PF02089.10 EMG48733.1 - 3.5e-58 196.7 0.1 4.5e-58 196.4 0.1 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.13 EMG48733.1 - 0.00096 18.5 0.0 0.021 14.1 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 2) FSH1 PF03959.8 EMG48733.1 - 0.001 18.5 0.4 0.032 13.6 0.3 2.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EMG48733.1 - 0.0014 18.5 0.0 0.0019 18.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EMG48733.1 - 0.0037 16.5 0.0 0.0059 15.9 0.0 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EMG48733.1 - 0.0039 16.8 0.0 0.017 14.7 0.0 2.0 1 1 0 1 1 1 1 PGAP1-like protein Lyase_1 PF00206.15 EMG48734.1 - 6.4e-10 38.7 0.0 7e-10 38.5 0.0 1.0 1 0 0 1 1 1 1 Lyase Adaptin_N PF01602.15 EMG48736.1 - 1.6e-99 333.6 8.8 2.3e-99 333.1 6.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EMG48736.1 - 1.5e-63 212.3 0.0 5.7e-63 210.4 0.0 2.0 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EMG48736.1 - 1.2e-55 187.0 1.2 1.2e-55 187.0 0.9 2.2 2 0 0 2 2 2 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EMG48736.1 - 6e-12 45.6 2.1 5.7e-07 29.7 0.0 4.8 4 2 2 6 6 6 2 HEAT repeats Cnd1 PF12717.2 EMG48736.1 - 3.3e-06 27.0 15.7 0.053 13.3 0.0 5.1 3 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EMG48736.1 - 2.3e-05 24.0 0.5 0.049 13.7 0.0 5.2 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 EMG48736.1 - 0.00037 20.9 0.3 2.2 8.8 0.0 4.9 3 1 1 4 4 4 1 HEAT-like repeat AP4E_app_platf PF14807.1 EMG48736.1 - 0.0047 17.1 0.1 0.028 14.6 0.0 2.4 2 0 0 2 2 2 1 Adaptin AP4 complex epsilon appendage platform Ribosomal_L7Ae PF01248.21 EMG48737.1 - 2.2e-26 91.1 0.4 3.7e-26 90.4 0.2 1.4 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EMG48737.1 - 0.00079 19.2 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 DUF438 PF04282.8 EMG48737.1 - 0.21 11.3 2.0 5.4 6.8 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF438) zf-UBR PF02207.15 EMG48738.1 - 2.8e-17 62.2 10.0 2.8e-17 62.2 6.9 1.9 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) zf-AD PF07776.10 EMG48738.1 - 0.05 13.6 4.7 3.1 7.8 0.0 2.9 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Lon_C PF05362.8 EMG48739.1 - 2.3e-65 219.7 0.0 6.6e-65 218.2 0.0 1.8 2 0 0 2 2 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EMG48739.1 - 1e-27 97.1 2.9 1e-27 97.1 2.0 2.6 2 1 1 3 3 3 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EMG48739.1 - 5.4e-21 75.1 0.1 3.1e-20 72.7 0.0 2.3 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMG48739.1 - 1.4e-08 34.5 0.0 5.6e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EMG48739.1 - 1.7e-06 27.5 0.0 5.1e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase RuvB_N PF05496.7 EMG48739.1 - 3.8e-06 26.1 0.0 0.00011 21.3 0.0 2.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_PrkA PF08298.6 EMG48739.1 - 6.9e-06 24.9 0.0 1.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.1 EMG48739.1 - 2.1e-05 24.5 0.7 0.00012 22.1 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EMG48739.1 - 6.3e-05 22.6 0.3 0.00027 20.6 0.2 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EMG48739.1 - 9.1e-05 22.6 0.2 0.00058 20.0 0.0 2.4 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.8 EMG48739.1 - 0.00013 20.8 1.3 0.001 17.8 0.1 2.5 2 0 0 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 EMG48739.1 - 0.00031 21.5 0.1 0.00031 21.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 EMG48739.1 - 0.00049 20.4 2.2 0.0042 17.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.6 EMG48739.1 - 0.00054 19.5 0.1 0.0099 15.4 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EMG48739.1 - 0.001 18.2 0.6 0.0043 16.1 0.1 2.1 2 0 0 2 2 2 1 Zeta toxin NTPase_1 PF03266.10 EMG48739.1 - 0.0018 18.0 0.0 0.023 14.3 0.0 2.6 1 1 1 2 2 2 1 NTPase Mg_chelatase PF01078.16 EMG48739.1 - 0.0019 17.4 0.1 0.033 13.3 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EMG48739.1 - 0.0024 17.3 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.7 EMG48739.1 - 0.0034 17.0 0.0 0.15 11.6 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.1 EMG48739.1 - 0.0073 16.2 0.0 0.031 14.1 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.1 EMG48739.1 - 0.009 15.6 0.9 0.021 14.3 0.1 2.0 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EMG48739.1 - 0.0092 15.6 0.1 0.026 14.1 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 EMG48739.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 EMG48739.1 - 0.016 15.3 0.0 0.061 13.5 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 EMG48739.1 - 0.018 14.4 0.2 0.039 13.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EMG48739.1 - 0.024 14.5 0.0 0.066 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EMG48739.1 - 0.034 14.1 0.4 0.41 10.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain TOM13 PF08219.6 EMG48740.1 - 2.6e-32 110.3 0.0 3.5e-32 109.9 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein TOM13 Hexokinase_2 PF03727.11 EMG48741.1 - 7.8e-96 319.9 0.0 1.7e-95 318.8 0.0 1.5 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.16 EMG48741.1 - 8.9e-80 266.8 0.0 1.3e-79 266.2 0.0 1.3 1 0 0 1 1 1 1 Hexokinase DIOX_N PF14226.1 EMG48742.1 - 7.9e-30 103.7 0.0 1.7e-29 102.7 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMG48742.1 - 1.2e-16 60.8 0.1 4.8e-16 58.8 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily V_ATPase_I PF01496.14 EMG48743.1 - 3.4 5.4 11.4 4.5 5.0 7.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WD40 PF00400.27 EMG48744.1 - 1.1e-65 215.2 18.8 1.2e-14 53.5 0.5 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EMG48744.1 - 1.1e-51 174.6 1.1 1.1e-51 174.6 0.8 1.9 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 EMG48744.1 - 1.7e-07 29.8 11.8 0.0082 14.3 0.0 4.8 4 1 1 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.6 EMG48744.1 - 4e-06 26.6 0.1 0.0054 16.4 0.0 3.2 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 EMG48744.1 - 1.2e-05 24.8 0.1 3.7e-05 23.3 0.1 1.9 1 0 0 1 1 1 1 LisH Med15 PF09606.5 EMG48744.1 - 0.33 9.1 41.5 0.084 11.0 13.4 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal LMBR1 PF04791.11 EMG48744.1 - 7.8 4.9 5.4 0.72 8.3 0.1 1.8 2 0 0 2 2 2 0 LMBR1-like membrane protein Rifin_STEVOR PF02009.11 EMG48745.1 - 0.098 12.2 9.5 0.13 11.8 6.6 1.2 1 0 0 1 1 1 0 Rifin/stevor family DUF883 PF05957.8 EMG48745.1 - 1.6 9.1 6.3 3.5 8.0 4.4 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) MCLC PF05934.6 EMG48745.1 - 2.9 6.0 7.2 3.3 5.9 5.0 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) SRP1_TIP1 PF00660.12 EMG48746.1 - 3.1e-15 55.8 0.2 5.5e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 Seripauperin and TIP1 family Atg14 PF10186.4 EMG48747.1 - 7.2e-07 28.4 2.4 1.2e-06 27.6 1.6 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 CENP-F_leu_zip PF10473.4 EMG48747.1 - 0.0064 16.3 5.6 0.014 15.2 3.9 1.5 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Snapin_Pallidin PF14712.1 EMG48747.1 - 0.099 12.9 13.8 0.35 11.1 1.0 3.2 1 1 2 3 3 3 0 Snapin/Pallidin IncA PF04156.9 EMG48747.1 - 0.32 10.5 9.2 0.64 9.5 6.4 1.4 1 0 0 1 1 1 0 IncA protein Reo_sigmaC PF04582.7 EMG48747.1 - 0.37 9.9 4.9 0.58 9.2 3.4 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein LPP PF04728.8 EMG48747.1 - 1.6 8.6 4.5 0.82 9.5 1.0 2.1 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF948 PF06103.6 EMG48747.1 - 2.3 8.1 8.4 3.1 7.7 3.8 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) SNF2_N PF00176.18 EMG48748.1 - 2.7e-70 236.5 0.9 6.5e-70 235.2 0.7 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 EMG48748.1 - 9.3e-52 174.7 22.4 9.3e-52 174.7 15.6 2.5 2 0 0 2 2 2 1 DNA-binding domain Helicase_C PF00271.26 EMG48748.1 - 2.2e-15 56.2 0.0 8.5e-15 54.3 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PNPOx_C PF10590.4 EMG48749.1 - 4.7e-18 64.3 2.3 8.6e-18 63.5 1.6 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EMG48749.1 - 1.4e-09 37.8 0.0 2.1e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 EMG48749.1 - 0.073 13.3 0.0 0.16 12.2 0.0 1.7 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Ribosomal_L32p PF01783.18 EMG48750.1 - 5.4e-12 45.7 3.8 8.9e-12 45.0 2.6 1.4 1 0 0 1 1 1 1 Ribosomal L32p protein family GATase_4 PF13230.1 EMG48750.1 - 0.012 14.3 0.0 0.021 13.4 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II zf-UBR PF02207.15 EMG48750.1 - 0.032 13.9 0.6 0.055 13.2 0.4 1.3 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DZR PF12773.2 EMG48750.1 - 0.065 13.0 0.5 0.12 12.2 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EMG48750.1 - 0.17 11.1 2.7 0.28 10.4 1.9 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Stc1 PF12898.2 EMG48750.1 - 0.43 10.6 3.3 0.28 11.2 0.4 2.0 3 0 0 3 3 3 0 Stc1 domain Septin PF00735.13 EMG48751.1 - 5.2e-111 370.1 0.7 6.2e-111 369.9 0.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EMG48751.1 - 3.6e-09 36.5 0.0 6.4e-09 35.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMG48751.1 - 4.7e-07 29.1 0.2 8.4e-07 28.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EMG48751.1 - 1e-06 28.0 0.9 1.7e-06 27.2 0.6 1.5 1 1 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 EMG48751.1 - 4.5e-05 22.9 0.2 0.00036 20.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 EMG48751.1 - 0.0015 18.0 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Miro PF08477.8 EMG48751.1 - 0.0017 18.8 0.7 0.0061 17.0 0.5 2.1 1 1 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EMG48751.1 - 0.0018 18.0 2.7 0.37 10.6 0.5 2.5 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 EMG48751.1 - 0.0019 17.6 0.4 0.003 17.0 0.3 1.4 1 1 0 1 1 1 1 AAA-like domain T2SE PF00437.15 EMG48751.1 - 0.0067 15.3 0.3 0.011 14.6 0.2 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 EMG48751.1 - 0.0094 16.2 1.9 0.014 15.6 0.4 2.0 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 EMG48751.1 - 0.011 15.6 0.1 0.028 14.4 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EMG48751.1 - 0.013 15.6 0.2 0.076 13.1 0.1 2.3 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EMG48751.1 - 0.02 13.7 0.4 0.041 12.7 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain Gtr1_RagA PF04670.7 EMG48751.1 - 0.036 13.2 0.3 0.085 11.9 0.2 1.8 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EMG48751.1 - 0.036 13.5 0.1 0.63 9.5 0.2 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EMG48751.1 - 0.048 13.2 0.1 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.17 EMG48751.1 - 0.077 12.3 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Ras family IIGP PF05049.8 EMG48751.1 - 0.079 11.7 1.4 0.097 11.4 0.1 1.7 1 1 1 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.1 EMG48751.1 - 0.091 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMG48751.1 - 0.098 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase FeoB_N PF02421.13 EMG48751.1 - 0.32 10.2 1.4 2.2 7.5 0.5 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B XPG_N PF00752.12 EMG48752.1 - 1e-32 112.3 0.0 1.8e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EMG48752.1 - 3.8e-27 94.1 0.1 7.8e-27 93.1 0.1 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EMG48752.1 - 1.3e-07 31.8 0.1 4.6e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold CLTH PF10607.4 EMG48752.1 - 0.1 12.3 0.3 13 5.5 0.0 2.2 2 0 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain Proteasome PF00227.21 EMG48753.1 - 1.8e-57 193.7 0.0 2.2e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMG48753.1 - 0.03 13.6 0.1 0.083 12.2 0.0 1.8 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature KN_motif PF12075.3 EMG48753.1 - 0.069 12.9 2.2 0.21 11.3 0.3 2.3 2 0 0 2 2 2 0 KN motif FumaraseC_C PF10415.4 EMG48754.1 - 5.9e-27 93.4 0.0 9.2e-27 92.8 0.0 1.3 1 0 0 1 1 1 1 Fumarase C C-terminus GATase_5 PF13507.1 EMG48755.1 - 9.8e-98 326.1 0.0 1.4e-97 325.6 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EMG48755.1 - 6.2e-42 143.1 0.5 1.3e-24 86.9 0.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EMG48755.1 - 1.2e-23 83.1 0.1 3.6e-23 81.6 0.0 2.0 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Tmemb_14 PF03647.8 EMG48756.1 - 5.1e-27 94.1 5.7 5.9e-27 93.9 4.0 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Peptidase_M50B PF13398.1 EMG48756.1 - 0.53 9.6 2.6 0.59 9.4 1.8 1.1 1 0 0 1 1 1 0 Peptidase M50B-like AA_permease_N PF08403.5 EMG48757.1 - 0.028 13.7 0.5 0.036 13.3 0.3 1.3 1 0 0 1 1 1 0 Amino acid permease N-terminal RNA_pol_Rpb8 PF03870.10 EMG48759.1 - 5.9e-45 152.8 0.1 6.7e-45 152.6 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 CsgG PF03783.9 EMG48759.1 - 0.094 11.7 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Curli production assembly/transport component CsgG PBP1_TM PF14812.1 EMG48760.1 - 5.7e-05 23.3 6.3 0.067 13.5 2.4 2.4 2 0 0 2 2 2 2 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1510 PF07423.6 EMG48760.1 - 0.0013 18.1 1.6 0.0017 17.7 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) U79_P34 PF03064.11 EMG48760.1 - 0.0061 16.1 1.1 0.0072 15.8 0.8 1.1 1 0 0 1 1 1 1 HSV U79 / HCMV P34 Vfa1 PF08432.5 EMG48760.1 - 0.027 14.5 4.5 0.034 14.1 3.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4131 PF13567.1 EMG48760.1 - 0.055 12.8 0.0 2.7 7.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DctQ PF04290.7 EMG48760.1 - 0.099 12.4 0.1 0.45 10.2 0.0 1.8 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Sporozoite_P67 PF05642.6 EMG48760.1 - 0.1 10.4 3.8 0.12 10.2 2.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.1 EMG48760.1 - 0.13 11.8 2.0 0.23 11.1 1.4 1.4 1 0 0 1 1 1 0 FAM176 family DUF912 PF06024.7 EMG48760.1 - 0.19 11.8 2.9 0.085 12.9 0.3 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CobT PF06213.7 EMG48760.1 - 0.6 9.1 8.7 0.72 8.9 6.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 EMG48760.1 - 1.3 7.0 9.8 1.5 6.7 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Herpes_LMP1 PF05297.6 EMG48760.1 - 5.5 5.7 8.4 10 4.9 5.8 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) MFS_1 PF07690.11 EMG48761.1 - 7e-06 24.9 25.0 1.8e-05 23.6 16.5 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily PspC PF04024.7 EMG48761.1 - 5.5 6.5 8.9 0.96 8.9 0.0 3.8 4 0 0 4 4 4 0 PspC domain DUF2462 PF09495.5 EMG48762.1 - 2.5e-25 89.0 11.9 2.5e-25 89.0 8.2 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) Ribosomal_S3_C PF00189.15 EMG48763.1 - 5.3e-15 55.4 0.2 1.1e-14 54.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EMG48763.1 - 6.5e-09 35.2 0.2 1.4e-08 34.1 0.2 1.6 1 0 0 1 1 1 1 KH domain Mannosyl_trans3 PF11051.3 EMG48764.1 - 3e-46 157.9 0.1 6.4e-46 156.8 0.1 1.6 1 0 0 1 1 1 1 Mannosyltransferase putative Guanylate_kin PF00625.16 EMG48764.1 - 0.0014 18.0 0.0 0.0034 16.8 0.0 1.6 1 0 0 1 1 1 1 Guanylate kinase PP2C PF00481.16 EMG48765.1 - 2.5e-54 184.3 0.0 3.2e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EMG48765.1 - 2.4e-05 23.8 0.0 9.2e-05 21.9 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C STAT_alpha PF01017.15 EMG48766.1 - 0.0022 17.7 0.4 0.0047 16.6 0.2 1.6 1 1 0 1 1 1 1 STAT protein, all-alpha domain Exo_endo_phos PF03372.18 EMG48767.1 - 3.6e-17 63.1 0.0 5.5e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1469 PF07332.6 EMG48767.1 - 0.14 11.9 3.3 0.24 11.1 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Spindle_Spc25 PF08234.7 EMG48768.1 - 8.1e-19 67.3 1.4 3.1e-18 65.5 1.0 2.1 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Spc7 PF08317.6 EMG48768.1 - 1.1e-05 24.2 6.8 1.1e-05 24.2 4.7 2.5 1 1 2 3 3 3 2 Spc7 kinetochore protein Reo_sigmaC PF04582.7 EMG48768.1 - 3.5e-05 23.1 3.2 5e-05 22.6 2.2 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein HAUS5 PF14817.1 EMG48768.1 - 0.0035 15.9 9.6 0.0054 15.3 6.7 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 HlyD PF00529.15 EMG48768.1 - 0.023 13.9 8.5 0.033 13.4 5.9 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Uds1 PF15456.1 EMG48768.1 - 0.14 12.1 11.8 0.09 12.7 6.4 2.0 1 1 0 1 1 1 0 Up-regulated During Septation DUF2229 PF09989.4 EMG48768.1 - 0.21 11.0 5.6 0.76 9.1 3.1 2.2 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Atg14 PF10186.4 EMG48768.1 - 0.21 10.4 16.0 0.36 9.7 11.1 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GvpK PF05121.7 EMG48768.1 - 0.35 10.7 9.6 0.094 12.5 2.9 2.8 1 1 1 3 3 3 0 Gas vesicle protein K Baculo_PEP_C PF04513.7 EMG48768.1 - 0.36 10.6 14.3 0.42 10.4 7.8 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IFT57 PF10498.4 EMG48768.1 - 0.39 9.3 25.0 0.76 8.4 0.5 2.3 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 MCPsignal PF00015.16 EMG48768.1 - 0.41 10.1 8.8 0.35 10.3 4.8 1.7 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain She9_MDM33 PF05546.6 EMG48768.1 - 0.47 9.9 15.3 0.22 11.0 8.1 2.2 2 1 1 3 3 3 0 She9 / Mdm33 family DUF479 PF04336.7 EMG48768.1 - 0.57 10.3 4.5 1.4 9.0 0.4 3.2 2 1 2 4 4 3 0 Protein of unknown function, DUF479 DUF4164 PF13747.1 EMG48768.1 - 0.91 9.7 17.2 4.5 7.4 1.9 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Prominin PF05478.6 EMG48768.1 - 1 6.8 16.4 1.4 6.3 11.4 1.2 1 0 0 1 1 1 0 Prominin zf-C4H2 PF10146.4 EMG48768.1 - 1.2 9.0 18.7 0.35 10.8 10.2 1.9 2 0 0 2 2 2 0 Zinc finger-containing protein UPF0184 PF03670.8 EMG48768.1 - 1.5 9.0 14.7 1.3 9.2 5.4 2.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) APG6 PF04111.7 EMG48768.1 - 3.6 6.5 26.1 1.1 8.1 14.6 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 HAUS6_N PF14661.1 EMG48768.1 - 3.7 6.8 16.7 4.9 6.4 3.2 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus TMPIT PF07851.8 EMG48768.1 - 4.4 6.2 14.8 0.68 8.9 6.5 2.1 1 1 1 2 2 2 0 TMPIT-like protein ALMT PF11744.3 EMG48768.1 - 5.3 5.5 7.3 7.9 5.0 5.1 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2935 PF11155.3 EMG48768.1 - 8.3 6.5 13.8 3.1e+02 1.4 9.4 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Pro_isomerase PF00160.16 EMG48769.1 - 5.7e-05 23.3 0.0 5.7e-05 23.3 0.0 2.5 2 2 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CDC45 PF02724.9 EMG48769.1 - 0.019 13.0 9.6 0.023 12.7 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RelB_N PF12910.2 EMG48769.1 - 0.022 14.1 0.1 0.056 12.8 0.0 1.7 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin stability system N-terminal Cytomega_UL84 PF06284.6 EMG48769.1 - 1.1 7.5 4.9 5.2 5.3 2.8 1.9 2 0 0 2 2 2 0 Cytomegalovirus UL84 protein CENP-T PF15511.1 EMG48769.1 - 1.4 8.0 10.0 1.5 8.0 4.8 1.9 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Presenilin PF01080.12 EMG48769.1 - 2.3 6.9 7.1 3.3 6.4 4.9 1.1 1 0 0 1 1 1 0 Presenilin Cwf_Cwc_15 PF04889.7 EMG48769.1 - 2.3 7.8 17.9 3.5 7.2 12.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 EMG48769.1 - 5.3 4.8 25.7 7.4 4.3 17.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2992 PF11208.3 EMG48771.1 - 0.0028 17.5 1.6 0.0044 16.9 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2992) UBA_e1_C PF09358.5 EMG48771.1 - 0.11 12.6 5.1 7.2 6.8 0.3 3.1 2 1 1 3 3 3 0 Ubiquitin-activating enzyme e1 C-terminal domain ATP-synt_ab PF00006.20 EMG48772.1 - 3.5e-61 206.4 0.0 4.6e-61 206.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EMG48772.1 - 1.6e-17 63.9 0.5 3.3e-17 62.9 0.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EMG48772.1 - 1e-12 48.0 1.5 2.2e-12 47.0 1.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EMG48772.1 - 0.00036 20.3 0.7 0.0012 18.7 0.5 1.9 1 0 0 1 1 1 1 HAS barrel domain DUF4473 PF14747.1 EMG48773.1 - 0.0011 19.1 0.4 0.0068 16.6 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4473) G-alpha PF00503.15 EMG48774.1 - 0.06 12.0 0.0 0.063 11.9 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Miro PF08477.8 EMG48774.1 - 0.065 13.7 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein DUF377 PF04041.8 EMG48775.1 - 3.3e-51 173.8 0.0 3.8e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF377) Glyco_hydro_32N PF00251.15 EMG48775.1 - 3e-08 33.3 1.9 1.4e-06 27.9 0.0 2.6 3 0 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.9 EMG48775.1 - 6.8e-06 25.3 0.1 0.82 8.6 0.0 3.9 3 1 1 4 4 4 3 Glycosyl hydrolases family 43 VPS9 PF02204.13 EMG48776.1 - 6.2e-11 42.2 6.2 6.2e-11 42.2 4.3 2.8 2 1 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Aconitase PF00330.15 EMG48779.1 - 3.1e-173 576.5 0.1 5.7e-173 575.6 0.0 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EMG48779.1 - 2e-42 144.4 0.1 3.5e-42 143.6 0.1 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain LRR_8 PF13855.1 EMG48780.1 - 7.6e-06 25.5 11.2 0.0051 16.5 2.9 3.7 2 1 1 3 3 3 3 Leucine rich repeat F-box-like PF12937.2 EMG48780.1 - 0.00035 20.2 0.3 0.0011 18.6 0.2 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EMG48780.1 - 0.00044 19.8 0.1 0.0017 17.9 0.1 2.0 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.2 EMG48780.1 - 0.01 15.4 16.9 1.1 8.9 5.8 3.9 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMG48780.1 - 0.11 12.6 10.2 0.92 9.7 0.1 4.4 3 1 0 3 3 3 0 Leucine Rich Repeat PEMT PF04191.8 EMG48781.1 - 6.1e-57 190.2 13.5 1e-34 118.7 1.9 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase CALCOCO1 PF07888.6 EMG48781.1 - 0.016 13.5 0.0 0.021 13.1 0.0 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like RNase_PH PF01138.16 EMG48782.1 - 2.3e-27 95.9 0.0 4e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 PRESAN PF09687.5 EMG48782.1 - 0.077 13.0 0.5 0.79 9.7 0.0 2.2 2 0 0 2 2 2 0 Plasmodium RESA N-terminal Imm45 PF15603.1 EMG48782.1 - 0.099 12.8 0.5 0.35 11.0 0.2 2.1 2 1 0 2 2 2 0 Immunity protein 45 OPT PF03169.10 EMG48783.1 - 6.3e-182 606.2 39.1 7.3e-182 606.0 27.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.10 EMG48784.1 - 2.4e-173 577.9 35.1 2.8e-173 577.7 24.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Cnd1 PF12717.2 EMG48785.1 - 0.00013 21.9 6.3 0.043 13.6 2.8 2.6 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EMG48785.1 - 0.0065 16.4 0.0 3.4 7.9 0.0 3.5 3 0 0 3 3 3 2 HEAT repeat zf-C2H2 PF00096.21 EMG48786.1 - 3e-20 71.2 27.6 3.9e-05 23.7 0.3 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMG48786.1 - 2.4e-19 68.6 37.5 1.5e-08 34.4 0.6 4.8 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMG48786.1 - 1.3e-13 50.2 24.4 0.0019 18.3 1.5 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 EMG48786.1 - 0.00094 19.3 0.1 0.00094 19.3 0.1 4.7 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EMG48786.1 - 0.0075 16.3 9.1 0.11 12.6 0.9 2.7 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EMG48786.1 - 0.33 10.9 19.9 0.13 12.1 1.1 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EMG48786.1 - 5.9 6.6 13.7 0.35 10.5 1.2 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type RNA_pol_L_2 PF13656.1 EMG48787.1 - 5.3e-30 102.6 0.0 7e-30 102.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EMG48787.1 - 4.1e-15 54.6 0.0 5.6e-15 54.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DEAD PF00270.24 EMG48788.1 - 2.5e-44 150.7 0.0 4.8e-43 146.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG48788.1 - 2.7e-23 81.6 0.0 2.7e-23 81.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMG48788.1 - 0.00084 19.2 0.0 0.0021 17.8 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EMG48788.1 - 0.0053 15.2 0.0 0.03 12.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) AAA_19 PF13245.1 EMG48788.1 - 0.056 13.2 0.1 4.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain Peptidase_S8 PF00082.17 EMG48789.1 - 6.1e-26 91.2 5.0 8.1e-26 90.8 3.4 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMG48789.1 - 0.00065 20.2 0.1 0.0034 17.9 0.0 2.1 2 0 0 2 2 2 1 Peptidase inhibitor I9 Hyphal_reg_CWP PF11765.3 EMG48790.1 - 2.9e-96 322.1 10.5 4.8e-96 321.4 7.3 1.4 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal ETRAMP PF09716.5 EMG48790.1 - 9.3 6.2 7.6 0.6 10.0 0.1 3.0 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Acetyltransf_1 PF00583.19 EMG48792.1 - 8.1e-10 38.6 0.0 1.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMG48792.1 - 1e-08 35.2 0.0 1.7e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMG48792.1 - 1.1e-05 25.5 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMG48792.1 - 0.00016 21.3 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EMG48792.1 - 0.007 16.2 0.1 0.018 14.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain OPT PF03169.10 EMG48793.1 - 8.1e-160 533.2 45.2 9.7e-160 533.0 31.4 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SID PF11778.3 EMG48793.1 - 5e-05 23.2 1.1 0.00013 21.8 0.7 1.7 1 0 0 1 1 1 1 Septation initiation Flagellin_N PF00669.15 EMG48793.1 - 0.014 15.2 0.4 0.19 11.5 0.6 2.3 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region OmpH PF03938.9 EMG48793.1 - 2.5 7.9 12.3 5.3 6.9 8.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.1 EMG48793.1 - 8.6 5.2 7.5 18 4.1 5.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Bax1-I PF01027.15 EMG48794.1 - 3.2e-46 157.5 31.4 3.7e-46 157.3 21.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4131 PF13567.1 EMG48794.1 - 0.72 9.2 13.6 1.6 8.0 3.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Collagen PF01391.13 EMG48795.1 - 0.14 11.7 11.7 0.3 10.6 8.1 1.7 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) CDC45 PF02724.9 EMG48796.1 - 0.05 11.6 1.2 0.057 11.4 0.8 1.0 1 0 0 1 1 1 0 CDC45-like protein SspB PF04386.8 EMG48796.1 - 0.065 12.8 1.6 0.094 12.3 1.1 1.1 1 0 0 1 1 1 0 Stringent starvation protein B SMN PF06003.7 EMG48796.1 - 0.077 12.0 9.6 0.1 11.6 6.6 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) CENP-B_dimeris PF09026.5 EMG48796.1 - 2.9 8.1 11.5 4.5 7.5 8.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 EMG48796.1 - 7.4 6.1 8.2 9.8 5.7 5.7 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Peptidase_S8 PF00082.17 EMG48797.1 - 3e-07 29.8 0.0 3e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 Subtilase family ICE2 PF08426.5 EMG48798.1 - 2e-129 431.8 13.3 2.6e-129 431.4 9.3 1.2 1 0 0 1 1 1 1 ICE2 Herpes_BLLF1 PF05109.8 EMG48798.1 - 0.36 8.7 17.8 0.49 8.3 12.3 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF1776 PF08643.5 EMG48799.1 - 8.7e-111 369.8 0.6 1.1e-110 369.4 0.4 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) STE2 PF02116.10 EMG48800.1 - 1.2e-74 250.9 19.7 1.6e-74 250.4 13.6 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR RGS PF00615.14 EMG48801.1 - 2.3e-11 43.8 0.2 3.9e-11 43.0 0.1 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain FNIP PF05725.7 EMG48802.1 - 0.51 10.3 13.5 2.5 8.1 0.1 4.2 3 0 0 3 3 3 0 FNIP Repeat LRR_7 PF13504.1 EMG48802.1 - 1.7 9.1 9.5 22 5.8 0.0 6.4 5 2 2 7 7 7 0 Leucine rich repeat LRR_1 PF00560.28 EMG48802.1 - 8 6.9 10.4 1.4e+02 3.1 2.6 5.6 3 1 0 3 3 3 0 Leucine Rich Repeat HMG_box PF00505.14 EMG48804.1 - 7.6e-18 64.5 0.5 7.6e-18 64.5 0.3 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMG48804.1 - 1.4e-08 34.9 0.1 1.4e-08 34.9 0.1 2.7 2 0 0 2 2 2 1 HMG-box domain COX4 PF02936.9 EMG48804.1 - 0.02 14.6 0.1 0.065 12.9 0.1 1.9 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Pantoate_ligase PF02569.10 EMG48805.1 - 4.1e-86 288.2 0.1 4.6e-86 288.0 0.1 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Phage_connector PF05352.7 EMG48805.1 - 0.083 12.0 0.0 0.15 11.2 0.0 1.6 1 1 0 1 1 1 0 Phage Connector (GP10) HA2 PF04408.18 EMG48806.1 - 4e-22 78.1 0.6 2.5e-21 75.5 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EMG48806.1 - 4.8e-19 68.2 0.6 1.3e-18 66.9 0.4 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EMG48806.1 - 3.9e-14 52.2 0.0 9.6e-14 51.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMG48806.1 - 2.7e-07 30.2 1.4 3.8e-07 29.7 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EMG48806.1 - 1e-06 28.9 0.1 3e-06 27.4 0.1 1.8 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 EMG48806.1 - 0.00019 21.1 0.0 0.00039 20.2 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_14 PF13173.1 EMG48806.1 - 0.0066 16.3 1.0 0.46 10.3 0.7 3.0 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EMG48806.1 - 0.012 14.5 0.0 0.026 13.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 EMG48806.1 - 0.018 14.1 0.0 0.042 12.9 0.0 1.5 1 0 0 1 1 1 0 KaiC SRP54 PF00448.17 EMG48806.1 - 0.038 13.4 0.0 0.083 12.3 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.1 EMG48806.1 - 0.082 12.4 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EMG48806.1 - 0.093 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMG48806.1 - 0.12 12.1 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 EMG48806.1 - 0.27 11.5 4.2 0.32 11.2 0.1 2.9 2 1 0 2 2 2 0 ABC transporter ResIII PF04851.10 EMG48806.1 - 1.1 9.1 8.7 2.5 7.8 1.2 3.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Nucleoporin_FG PF13634.1 EMG48807.1 - 2.5e-46 156.5 308.2 8.3e-15 55.0 32.6 4.8 1 1 5 6 6 6 6 Nucleoporin FG repeat region Nup54 PF13874.1 EMG48807.1 - 7.3e-45 152.0 0.9 1.7e-44 150.9 0.1 1.9 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Colipase-like PF15083.1 EMG48808.1 - 0.012 15.5 3.0 0.019 14.9 2.1 1.3 1 0 0 1 1 1 0 Colipase-like CHCH PF06747.8 EMG48808.1 - 0.053 13.4 4.4 0.053 13.4 3.0 2.8 3 0 0 3 3 3 0 CHCH domain Pet191_N PF10203.4 EMG48808.1 - 2.1 8.4 6.8 43 4.2 4.1 2.8 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 EMG48808.1 - 2.4 8.2 10.7 1.6 8.8 3.1 2.4 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb COG2 PF06148.6 EMG48809.1 - 1.8e-13 50.5 1.4 1.8e-13 50.5 1.0 1.5 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Recep_L_domain PF01030.19 EMG48809.1 - 0.0089 15.9 2.1 0.0089 15.9 1.5 1.8 2 0 0 2 2 2 1 Receptor L domain Vps51 PF08700.6 EMG48809.1 - 0.043 13.6 0.5 0.043 13.6 0.3 1.7 2 0 0 2 2 2 0 Vps51/Vps67 Fungal_trans PF04082.13 EMG48810.1 - 2.4e-35 121.6 1.6 2.4e-35 121.6 1.1 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG48810.1 - 8.4e-10 38.3 11.1 8.4e-10 38.3 7.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pigment_DH PF06324.6 EMG48810.1 - 0.0003 19.9 0.1 0.0003 19.9 0.1 2.0 2 0 0 2 2 2 1 Pigment-dispersing hormone (PDH) Abhydrolase_6 PF12697.2 EMG48811.1 - 9.9e-25 87.7 0.0 1.2e-24 87.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMG48811.1 - 2.8e-08 33.6 0.0 5.5e-08 32.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMG48811.1 - 3.2e-07 30.1 0.0 4.3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EMG48811.1 - 1.4e-05 24.6 0.0 1.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DUF2920 PF11144.3 EMG48811.1 - 0.0019 17.2 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Peptidase_S9 PF00326.16 EMG48811.1 - 0.0034 16.6 0.0 0.0097 15.1 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EMG48811.1 - 0.0062 16.0 0.0 0.11 11.9 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase PGAP1 PF07819.8 EMG48811.1 - 0.026 14.0 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Ribosomal_S19 PF00203.16 EMG48811.1 - 0.095 12.3 0.1 0.56 9.8 0.0 2.3 3 0 0 3 3 3 0 Ribosomal protein S19 Lyase_1 PF00206.15 EMG48813.1 - 5.7e-24 84.8 0.0 8.3e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EMG48813.1 - 5e-16 58.4 0.0 1.8e-15 56.7 0.0 2.0 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.6 EMG48813.1 - 0.055 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) AsiA PF09010.5 EMG48813.1 - 0.097 12.5 0.1 0.57 10.0 0.0 2.1 2 0 0 2 2 2 0 Anti-Sigma Factor A DASH_Dad3 PF08656.5 EMG48814.1 - 2.1e-22 78.6 4.1 3e-22 78.0 2.8 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad3 Katanin_con80 PF13925.1 EMG48814.1 - 0.013 15.2 0.3 0.026 14.2 0.2 1.5 1 1 0 1 1 1 0 con80 domain of Katanin DUF3461 PF11944.3 EMG48814.1 - 0.036 13.8 1.1 0.063 13.1 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) WD40 PF00400.27 EMG48816.1 - 1.1e-27 94.8 14.5 8.5e-09 34.9 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat PD40 PF07676.7 EMG48816.1 - 2.1e-07 30.4 2.0 0.72 9.5 0.0 5.3 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 EMG48816.1 - 0.0042 16.5 0.0 0.014 14.7 0.0 1.9 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain DPPIV_N PF00930.16 EMG48816.1 - 0.012 14.1 0.3 9.3 4.7 0.0 3.4 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF3312 PF11768.3 EMG48816.1 - 0.016 13.4 0.0 0.024 12.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3312) Rax2 PF12768.2 EMG48816.1 - 0.048 12.8 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Cortical protein marker for cell polarity eIF2A PF08662.6 EMG48816.1 - 0.052 13.2 0.1 1 9.0 0.0 2.7 2 2 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 EMG48816.1 - 5.7 6.3 5.8 29 4.1 0.0 3.9 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Cation_efflux PF01545.16 EMG48817.1 - 5.4e-34 117.5 9.8 7.4e-34 117.1 6.8 1.1 1 0 0 1 1 1 1 Cation efflux family Zn_clus PF00172.13 EMG48818.1 - 0.00019 21.2 11.0 0.00034 20.4 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EMG48818.1 - 1.9 8.7 12.0 2.2 8.5 3.1 2.5 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Ribosomal_L30 PF00327.15 EMG48819.1 - 2.7e-10 39.6 0.8 7.2e-10 38.3 0.5 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Rgp1 PF08737.5 EMG48819.1 - 0.54 9.2 7.2 0.79 8.7 5.0 1.3 1 0 0 1 1 1 0 Rgp1 Lge1 PF11488.3 EMG48820.1 - 1.4e-22 79.6 3.0 2.4e-22 78.8 2.1 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 adh_short PF00106.20 EMG48821.1 - 2.4e-19 69.8 0.0 3.4e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMG48821.1 - 7.4e-11 42.2 0.4 1.2e-10 41.5 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMG48821.1 - 0.00057 19.9 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EMG48821.1 - 0.00071 19.2 0.2 0.004 16.8 0.1 2.0 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EMG48821.1 - 0.023 13.5 0.4 0.032 13.1 0.3 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1863 PF08937.6 EMG48821.1 - 0.044 13.8 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) Shikimate_DH PF01488.15 EMG48821.1 - 0.057 13.5 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MUG2_C PF08593.5 EMG48821.1 - 0.17 12.1 0.4 0.56 10.4 0.1 1.9 2 0 0 2 2 2 0 Meiotically up-regulated glycoproteins C-terminal DnaJ PF00226.26 EMG48822.1 - 1.5e-24 85.5 1.0 2.2e-24 84.9 0.7 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EMG48822.1 - 9.6e-24 83.0 0.2 2.8e-20 72.0 0.0 2.5 2 1 0 2 2 2 2 DnaJ C terminal domain Malate_DH PF12434.3 EMG48822.1 - 0.042 13.5 0.2 0.086 12.5 0.1 1.6 1 0 0 1 1 1 0 Malate dehydrogenase enzyme WD40 PF00400.27 EMG48823.1 - 8.4e-46 152.2 16.9 1.2e-10 40.8 0.4 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EMG48823.1 - 1.1e-09 36.9 13.8 0.011 13.8 0.1 5.0 3 2 2 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMG48823.1 - 9e-06 24.6 5.8 0.2 10.3 0.0 4.0 1 1 2 4 4 4 3 Nup133 N terminal like DUF3312 PF11768.3 EMG48823.1 - 0.00018 19.9 0.4 0.002 16.4 0.0 2.4 1 1 2 3 3 3 1 Protein of unknown function (DUF3312) Hira PF07569.6 EMG48823.1 - 0.049 12.8 7.8 1.7 7.7 0.0 3.9 2 1 3 5 5 5 0 TUP1-like enhancer of split SET PF00856.23 EMG48824.1 - 0.0088 16.3 0.4 0.026 14.8 0.2 1.9 2 0 0 2 2 2 1 SET domain RFX_DNA_binding PF02257.10 EMG48825.1 - 4.7e-32 109.9 0.0 1.2e-31 108.6 0.0 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.11 EMG48825.1 - 0.031 14.5 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 Poxvirus D5 protein-like Cpn60_TCP1 PF00118.19 EMG48826.1 - 1.6e-116 389.8 8.9 1.8e-116 389.6 6.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rrf2 PF02082.15 EMG48826.1 - 0.042 13.9 0.1 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator Mito_fiss_reg PF05308.6 EMG48827.1 - 0.05 12.9 0.1 0.067 12.5 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Acyl-CoA_ox_N PF14749.1 EMG48827.1 - 0.1 12.9 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Viral_P18 PF04521.8 EMG48828.1 - 0.097 12.1 1.8 0.4 10.1 0.1 2.3 2 1 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Ras PF00071.17 EMG48829.1 - 3.5e-55 185.7 0.5 4.3e-55 185.5 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMG48829.1 - 6.2e-21 75.1 0.4 1.3e-20 74.0 0.1 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMG48829.1 - 8e-15 54.5 0.7 1e-14 54.1 0.5 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMG48829.1 - 2.8e-06 26.6 0.3 4e-06 26.1 0.2 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EMG48829.1 - 5.3e-06 26.0 0.1 4.9e-05 22.8 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMG48829.1 - 1.6e-05 24.1 0.5 2e-05 23.8 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMG48829.1 - 9.6e-05 22.3 0.0 0.00015 21.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EMG48829.1 - 0.0025 17.5 0.6 0.01 15.5 0.4 1.8 1 1 0 1 1 1 1 Archaeal ATPase PduV-EutP PF10662.4 EMG48829.1 - 0.0028 17.1 0.8 0.077 12.4 0.6 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF3048 PF11258.3 EMG48829.1 - 0.0087 15.2 0.1 0.02 14.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3048) Antitoxin-MazE PF04014.13 EMG48829.1 - 0.027 14.1 0.4 0.063 13.0 0.3 1.6 1 0 0 1 1 1 0 Antidote-toxin recognition MazE FeoB_N PF02421.13 EMG48829.1 - 0.033 13.4 0.1 4.3 6.5 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B dsDNA_bind PF01984.15 EMG48830.1 - 6.6e-33 112.9 11.9 7.6e-33 112.7 8.2 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF1870 PF08965.5 EMG48830.1 - 0.068 12.8 0.2 0.087 12.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) EF-1_beta_acid PF10587.4 EMG48830.1 - 0.1 12.7 1.0 0.1 12.7 0.7 2.8 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Kinesin PF00225.18 EMG48831.1 - 3.6e-103 344.7 9.3 3.6e-103 344.7 6.4 2.9 3 0 0 3 3 3 1 Kinesin motor domain ALIX_LYPXL_bnd PF13949.1 EMG48831.1 - 0.86 8.5 36.5 3 6.7 0.4 4.0 1 1 2 3 3 3 0 ALIX V-shaped domain binding to HIV DUF4140 PF13600.1 EMG48831.1 - 1.4 9.4 5.3 4.1 7.9 1.1 2.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF947 PF06102.7 EMG48831.1 - 4.9 6.9 24.9 10 5.8 0.9 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF947) Pox_A_type_inc PF04508.7 EMG48831.1 - 9.6 6.2 18.8 0.17 11.7 0.5 5.2 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Clp1 PF06807.9 EMG48832.1 - 1.1e-05 25.2 0.0 2.4e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MMR_HSR1 PF01926.18 EMG48832.1 - 8.4e-05 22.5 0.2 0.00031 20.6 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMG48832.1 - 0.00057 19.7 0.9 0.0016 18.2 0.0 2.1 2 0 0 2 2 2 1 Dynamin family MobB PF03205.9 EMG48832.1 - 0.0013 18.4 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.13 EMG48832.1 - 0.0019 17.2 0.0 0.0037 16.3 0.0 1.4 1 0 0 1 1 1 1 Septin RNA_helicase PF00910.17 EMG48832.1 - 0.01 15.9 0.0 0.076 13.1 0.0 2.6 1 1 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 EMG48832.1 - 0.013 15.4 0.0 0.04 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EMG48832.1 - 0.014 14.6 0.3 3.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B FtsK_SpoIIIE PF01580.13 EMG48832.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Miro PF08477.8 EMG48832.1 - 0.019 15.4 0.0 0.043 14.3 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein PPV_E1_C PF00519.12 EMG48832.1 - 0.071 11.7 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_17 PF13207.1 EMG48832.1 - 0.072 13.9 0.0 0.25 12.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.21 EMG48832.1 - 0.085 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain GST_N_3 PF13417.1 EMG48833.1 - 2e-10 40.7 0.0 3.3e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMG48833.1 - 4.3e-10 39.3 0.3 9e-10 38.3 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMG48833.1 - 8.6e-10 38.4 0.2 1.5e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMG48833.1 - 2.4e-09 37.0 0.0 5.3e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMG48833.1 - 2e-08 34.2 0.0 4.3e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMG48833.1 - 4.4e-06 27.0 0.1 6.6e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EMG48833.1 - 0.1 12.9 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 MetRS-N binding domain zf-rbx1 PF12678.2 EMG48834.1 - 2.8e-11 43.3 0.6 5e-11 42.5 0.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EMG48834.1 - 7.3e-11 41.7 5.0 1.9e-10 40.3 3.5 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMG48834.1 - 5.6e-07 29.1 2.9 4.7e-05 22.9 0.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMG48834.1 - 4.4e-06 26.3 1.4 8.9e-06 25.3 1.0 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMG48834.1 - 3.1e-05 23.5 3.8 5.5e-05 22.7 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMG48834.1 - 6.1e-05 22.9 1.5 6.1e-05 22.9 1.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMG48834.1 - 0.001 18.7 2.3 0.0027 17.3 1.6 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EMG48834.1 - 0.0014 18.4 2.6 0.006 16.3 1.8 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EMG48834.1 - 0.011 15.5 0.7 0.011 15.5 0.5 1.7 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EMG48834.1 - 0.028 14.3 2.4 0.13 12.2 1.7 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain PGA2 PF07543.7 EMG48834.1 - 0.045 13.5 1.0 0.084 12.6 0.7 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 RINGv PF12906.2 EMG48834.1 - 0.23 11.5 4.3 0.97 9.5 3.0 2.0 1 1 0 1 1 1 0 RING-variant domain zf-P11 PF03854.9 EMG48834.1 - 0.23 10.9 2.8 0.29 10.6 0.6 2.0 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_4 PF14570.1 EMG48834.1 - 0.51 9.9 1.8 0.82 9.3 0.4 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PAT1 PF09770.4 EMG48834.1 - 0.63 8.2 5.5 0.95 7.6 3.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RNA_pol_I_TF PF04090.7 EMG48835.1 - 4.3e-59 199.1 3.9 8.8e-59 198.1 2.2 1.9 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor MADF_DNA_bdg PF10545.4 EMG48835.1 - 0.048 13.8 2.5 0.18 11.9 1.7 2.0 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Metallophos PF00149.23 EMG48836.1 - 3.2e-38 131.1 0.1 4.2e-38 130.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GldM_N PF12081.3 EMG48837.1 - 0.015 14.8 0.3 0.11 11.9 0.1 2.0 2 0 0 2 2 2 0 GldM N-terminal domain Phage_GPO PF05929.6 EMG48837.1 - 0.13 11.5 0.1 0.37 9.9 0.0 1.7 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase zf-C2H2_4 PF13894.1 EMG48838.1 - 3.8e-10 39.3 9.8 1.5e-05 25.0 1.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EMG48838.1 - 9.6e-09 35.0 18.6 1.6e-05 24.9 1.3 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMG48838.1 - 1e-08 34.9 4.8 1e-08 34.9 3.3 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EMG48838.1 - 1.7e-06 27.7 4.9 3.5e-06 26.7 0.2 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.7 EMG48838.1 - 0.0019 18.2 0.4 0.0019 18.2 0.3 1.8 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EMG48838.1 - 0.035 14.2 0.4 0.035 14.2 0.3 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 EMG48838.1 - 0.32 10.6 5.5 0.07 12.7 0.5 2.5 2 1 1 3 3 3 0 GAGA factor zf-met PF12874.2 EMG48838.1 - 2.5 8.4 5.2 22 5.4 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Pkinase PF00069.20 EMG48841.1 - 8.2e-75 251.3 0.0 9.3e-75 251.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG48841.1 - 6.6e-31 107.3 0.0 8.4e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG48841.1 - 0.00013 21.0 0.0 0.00024 20.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EMG48841.1 - 0.00014 20.8 0.2 0.00022 20.1 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EMG48841.1 - 0.0062 16.3 0.0 0.013 15.1 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EMG48841.1 - 0.023 13.7 0.1 0.048 12.7 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1892 PF08987.5 EMG48843.1 - 5.2e-32 110.2 10.1 5.2e-32 110.2 7.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1892) PDCD2_C PF04194.8 EMG48843.1 - 0.052 13.1 0.1 0.052 13.1 0.1 2.0 1 1 1 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain DUF2201_N PF13203.1 EMG48843.1 - 0.14 11.3 0.5 0.17 11.0 0.4 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain PBP1_TM PF14812.1 EMG48843.1 - 0.41 10.9 10.1 0.89 9.9 7.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.6 EMG48843.1 - 0.57 7.9 3.6 0.52 8.1 2.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nro1 PF12753.2 EMG48843.1 - 0.82 8.5 12.4 1.4 7.7 8.6 1.5 1 1 0 1 1 1 0 Nuclear pore complex subunit Nro1 Rep_4 PF05797.6 EMG48843.1 - 1.5 7.4 7.1 5.1 5.6 5.0 1.7 1 1 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Nucleoplasmin PF03066.10 EMG48843.1 - 7.8 6.0 16.7 9.5 5.7 11.6 1.3 1 1 0 1 1 1 0 Nucleoplasmin PGI PF00342.14 EMG48844.1 - 3.2e-221 734.9 0.9 3.6e-221 734.7 0.6 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Mhr1 PF12829.2 EMG48844.1 - 0.0019 17.9 0.1 0.024 14.4 0.0 2.3 2 0 0 2 2 2 1 Transcriptional regulation of mitochondrial recombination Pkinase PF00069.20 EMG48845.1 - 4.4e-65 219.3 0.0 7.3e-65 218.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG48845.1 - 1.3e-27 96.5 0.0 2e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG48845.1 - 0.00072 18.6 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMG48845.1 - 0.024 13.7 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RAB3GAP2_N PF14655.1 EMG48845.1 - 5.3 5.9 6.8 0.94 8.4 0.3 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus LcrG PF07216.7 EMG48845.1 - 6.8 6.7 8.3 4.6 7.3 0.7 2.7 2 0 0 2 2 2 0 LcrG protein Tcp11 PF05794.8 EMG48846.1 - 5.1e-157 523.0 14.1 8.6e-157 522.3 9.8 1.3 1 0 0 1 1 1 1 T-complex protein 11 DUF3186 PF11382.3 EMG48847.1 - 0.023 13.8 0.3 0.055 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3186) Endotoxin_C PF03944.9 EMG48848.1 - 0.075 13.1 1.3 0.17 12.0 0.9 1.6 1 0 0 1 1 1 0 delta endotoxin Glyco_hydro_92 PF07971.7 EMG48849.1 - 8.8e-164 545.8 9.4 1.1e-163 545.5 6.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 HSF_DNA-bind PF00447.12 EMG48850.1 - 1e-33 115.5 8.7 1e-33 115.5 6.0 2.1 2 0 0 2 2 2 1 HSF-type DNA-binding Oxidored_FMN PF00724.15 EMG48851.1 - 4.8e-74 249.3 0.0 5.8e-74 249.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF2673 PF10880.3 EMG48851.1 - 0.099 12.6 0.1 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) Oxidored_FMN PF00724.15 EMG48852.1 - 1.1e-77 261.4 0.0 1.3e-77 261.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 EMG48852.1 - 0.053 12.8 0.0 2.2 7.5 0.0 2.5 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel LRR_6 PF13516.1 EMG48853.1 - 6.7e-05 22.5 0.5 0.31 11.2 0.1 4.2 2 0 0 2 2 2 2 Leucine Rich repeat LRR_4 PF12799.2 EMG48853.1 - 0.0015 18.1 16.9 0.024 14.2 1.5 5.2 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMG48853.1 - 0.028 14.3 9.5 1.1 9.5 0.1 5.8 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 EMG48853.1 - 0.13 12.5 4.8 0.93 9.9 0.0 4.5 4 0 0 4 4 4 0 Leucine rich repeat Elf1 PF05129.8 EMG48854.1 - 3.9e-30 103.3 2.0 4.9e-30 103.0 1.4 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Ribosomal_L37ae PF01780.14 EMG48854.1 - 0.043 13.6 0.5 0.058 13.2 0.3 1.2 1 0 0 1 1 1 0 Ribosomal L37ae protein family Pox_A51 PF04948.8 EMG48854.1 - 0.044 12.4 0.7 0.057 12.0 0.5 1.1 1 0 0 1 1 1 0 Poxvirus A51 protein EST1_DNA_bind PF10373.4 EMG48854.1 - 0.14 11.3 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Zn-ribbon_8 PF09723.5 EMG48854.1 - 0.16 11.9 2.0 0.64 10.0 1.4 2.0 1 1 0 1 1 1 0 Zinc ribbon domain zf-C2H2_6 PF13912.1 EMG48854.1 - 0.22 11.4 3.4 0.64 10.0 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EMG48854.1 - 0.25 11.4 3.5 4.4 7.4 0.4 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) NAP PF00956.13 EMG48856.1 - 1.1e-32 113.1 8.4 1.8e-32 112.4 5.8 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) FOP_dimer PF09398.5 EMG48856.1 - 0.29 11.1 2.6 0.53 10.3 0.2 2.3 2 0 0 2 2 2 0 FOP N terminal dimerisation domain Nucleoplasmin PF03066.10 EMG48856.1 - 1.7 8.1 7.6 0.33 10.4 2.5 1.9 2 0 0 2 2 2 0 Nucleoplasmin RXT2_N PF08595.6 EMG48856.1 - 3.8 7.2 8.3 7.1 6.4 2.3 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal HTH_Tnp_Tc3_2 PF01498.13 EMG48857.1 - 2.4e-07 30.6 2.2 0.00038 20.4 0.1 2.5 2 0 0 2 2 2 2 Transposase HTH_29 PF13551.1 EMG48857.1 - 3.3e-06 27.2 0.6 5.6e-06 26.4 0.4 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EMG48857.1 - 7.1e-06 26.7 2.6 3.6e-05 24.4 0.5 2.3 1 1 1 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EMG48857.1 - 8.7e-06 25.5 0.1 0.027 14.3 0.0 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_24 PF13412.1 EMG48857.1 - 1.7e-05 24.1 2.8 0.0068 15.7 0.1 2.4 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_23 PF13384.1 EMG48857.1 - 5.2e-05 22.7 0.6 0.0096 15.5 0.1 2.6 2 1 0 2 2 2 1 Homeodomain-like domain DDRGK PF09756.4 EMG48857.1 - 7.1e-05 22.2 1.9 0.00012 21.5 1.3 1.5 1 1 0 1 1 1 1 DDRGK domain HTH_11 PF08279.7 EMG48857.1 - 0.00018 21.0 1.8 0.023 14.3 0.1 2.4 2 0 0 2 2 2 1 HTH domain HTH_38 PF13936.1 EMG48857.1 - 0.0002 20.8 5.7 0.00044 19.7 0.3 3.2 3 1 0 3 3 3 1 Helix-turn-helix domain HTH_17 PF12728.2 EMG48857.1 - 0.0005 20.2 0.3 0.0046 17.1 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.2 EMG48857.1 - 0.0025 17.4 0.3 0.21 11.2 0.0 2.4 2 0 0 2 2 2 1 MarR family Sigma70_ECF PF07638.6 EMG48857.1 - 0.0051 16.4 0.6 0.024 14.3 0.1 2.1 1 1 1 2 2 2 1 ECF sigma factor MarR PF01047.17 EMG48857.1 - 0.0095 15.6 0.3 4 7.2 0.0 2.4 2 0 0 2 2 2 1 MarR family HTH_10 PF04967.7 EMG48857.1 - 0.011 15.2 0.2 0.083 12.4 0.0 2.5 2 1 2 4 4 4 0 HTH DNA binding domain NUMOD1 PF07453.8 EMG48857.1 - 0.012 15.3 0.0 0.049 13.4 0.0 2.0 2 0 0 2 2 2 0 NUMOD1 domain HTH_28 PF13518.1 EMG48857.1 - 0.018 15.0 0.1 0.8 9.7 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Fe_dep_repress PF01325.14 EMG48857.1 - 0.029 14.3 0.4 0.96 9.4 0.0 2.4 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_5 PF01022.15 EMG48857.1 - 0.056 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Sigma70_r4 PF04545.11 EMG48857.1 - 0.08 12.2 0.5 0.23 10.8 0.3 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 GntR PF00392.16 EMG48857.1 - 0.11 11.9 0.4 0.29 10.5 0.1 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family UCH PF00443.24 EMG48858.1 - 5.7e-49 166.6 4.0 2.6e-48 164.4 2.8 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EMG48858.1 - 7.5e-37 124.5 12.2 3.8e-18 64.6 0.2 5.0 4 0 0 4 4 4 3 A repeated domain in UCH-protein UCH_1 PF13423.1 EMG48858.1 - 1.1e-09 38.1 8.3 2.7e-06 27.0 0.2 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RcsC PF09456.5 EMG48858.1 - 0.033 13.8 1.0 3.8 7.2 0.1 3.3 3 0 0 3 3 3 0 RcsC Alpha-Beta-Loop (ABL) BCS1_N PF08740.6 EMG48859.1 - 6.4e-47 159.5 0.0 1.3e-46 158.6 0.0 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EMG48859.1 - 2.9e-22 79.2 0.0 4.8e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMG48859.1 - 3.9e-06 27.6 0.0 1.5e-05 25.7 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EMG48859.1 - 0.00023 21.4 0.0 0.0012 19.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMG48859.1 - 0.00027 21.0 0.0 0.00042 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 EMG48859.1 - 0.00041 19.3 0.0 0.00064 18.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_21 PF13304.1 EMG48859.1 - 0.00053 20.0 0.2 0.0015 18.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMG48859.1 - 0.00055 19.8 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMG48859.1 - 0.0021 18.1 0.0 0.0061 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EMG48859.1 - 0.0043 16.4 0.0 0.0077 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMG48859.1 - 0.0044 16.7 0.0 0.012 15.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EMG48859.1 - 0.0053 15.8 0.0 0.0091 15.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 EMG48859.1 - 0.0055 16.4 0.0 0.026 14.2 0.0 2.1 1 1 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EMG48859.1 - 0.0063 15.5 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus ABC_tran PF00005.22 EMG48859.1 - 0.008 16.4 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Miro PF08477.8 EMG48859.1 - 0.012 16.1 0.0 0.046 14.2 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 EMG48859.1 - 0.013 14.9 0.0 0.036 13.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 EMG48859.1 - 0.014 15.0 0.0 0.045 13.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.1 EMG48859.1 - 0.02 15.1 0.0 0.059 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EMG48859.1 - 0.022 14.6 0.0 0.049 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EMG48859.1 - 0.023 14.3 0.0 0.09 12.4 0.0 1.8 1 1 0 2 2 2 0 Archaeal ATPase MetJ PF01340.15 EMG48859.1 - 0.023 14.4 0.1 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Met Apo-repressor, MetJ RNA_helicase PF00910.17 EMG48859.1 - 0.028 14.5 0.0 0.068 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 EMG48859.1 - 0.033 13.2 0.0 0.076 12.1 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_28 PF13521.1 EMG48859.1 - 0.042 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EMG48859.1 - 0.05 13.2 0.0 0.54 9.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 EMG48859.1 - 0.094 12.2 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EMG48859.1 - 0.098 12.3 0.0 0.27 10.8 0.0 1.7 2 0 0 2 2 2 0 NACHT domain ABC2_membrane PF01061.19 EMG48860.1 - 4.7e-35 120.6 13.6 4.7e-35 120.6 9.4 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EMG48860.1 - 4e-27 95.1 0.0 7.9e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EMG48860.1 - 2.2e-09 37.7 1.4 2.2e-09 37.7 1.0 2.6 2 1 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 EMG48860.1 - 2.4e-06 26.8 21.5 2.4e-06 26.8 14.9 1.8 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_15 PF13175.1 EMG48860.1 - 0.0013 17.8 0.1 0.63 9.0 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EMG48860.1 - 0.0026 17.1 0.0 1 8.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EMG48860.1 - 0.0041 17.1 0.0 0.009 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EMG48860.1 - 0.0085 15.2 0.1 0.029 13.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EMG48860.1 - 0.025 14.1 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.1 EMG48860.1 - 0.025 14.4 0.0 0.067 13.1 0.0 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit T2SE PF00437.15 EMG48860.1 - 0.064 12.1 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.1 EMG48860.1 - 0.075 12.9 0.5 0.14 12.1 0.4 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMG48860.1 - 0.11 12.8 0.1 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EMG48860.1 - 0.15 12.1 0.1 0.33 11.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.20 EMG48861.1 - 4.5e-72 242.3 0.0 6.7e-72 241.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG48861.1 - 1.4e-32 112.7 0.0 1.9e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMG48861.1 - 0.0017 18.1 0.1 0.017 14.8 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EMG48861.1 - 0.011 14.7 0.5 0.017 14.1 0.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EMG48861.1 - 0.018 14.3 0.6 0.031 13.6 0.4 1.3 1 0 0 1 1 1 0 RIO1 family DUF2470 PF10615.4 EMG48863.1 - 8.3e-16 57.9 0.1 1.2e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Voltage_CLC PF00654.15 EMG48864.1 - 2.5e-98 329.4 27.6 5.1e-98 328.3 14.7 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel MT-A70 PF05063.9 EMG48865.1 - 4.8e-13 49.0 0.0 8.5e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 MT-A70 Glucosaminidase PF01832.15 EMG48865.1 - 0.027 14.5 0.9 0.058 13.5 0.6 1.5 1 0 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase MFS_1 PF07690.11 EMG48866.1 - 1.6e-34 119.1 34.0 1.6e-34 119.1 23.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily FA_hydroxylase PF04116.8 EMG48868.1 - 5.9e-15 55.6 23.4 5.9e-15 55.6 16.2 2.1 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily VirB3 PF05101.8 EMG48868.1 - 0.13 12.2 0.2 3.5 7.6 0.0 2.5 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein Iso_dh PF00180.15 EMG48869.1 - 1.7e-72 244.2 0.0 2e-72 244.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2543 PF10820.3 EMG48869.1 - 0.061 13.3 0.7 0.15 12.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2543) His_Phos_2 PF00328.17 EMG48870.1 - 6.3e-31 107.9 0.0 7.3e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Fcf1 PF04900.7 EMG48871.1 - 9.9e-34 115.4 0.9 9.9e-34 115.4 0.6 1.8 2 0 0 2 2 2 1 Fcf1 R3H PF01424.17 EMG48872.1 - 9.2e-11 41.2 0.0 1.8e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 EMG48872.1 - 2.2e-05 24.2 10.6 2.2e-05 24.2 7.4 11.9 13 1 0 13 13 13 3 NF-X1 type zinc finger Pkinase PF00069.20 EMG48873.1 - 2.5e-69 233.3 0.0 6.3e-69 232.0 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG48873.1 - 3.5e-41 141.0 0.0 6.3e-41 140.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG48873.1 - 4.1e-09 35.7 0.0 7.6e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMG48873.1 - 0.0016 17.5 0.0 0.0029 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMG48873.1 - 0.023 14.4 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Rubis-subs-bind PF09273.6 EMG48874.1 - 0.0025 17.7 0.8 0.021 14.7 0.2 2.6 2 1 0 2 2 2 1 Rubisco LSMT substrate-binding Abhydrolase_1 PF00561.15 EMG48875.1 - 2e-38 132.2 0.0 2.4e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMG48875.1 - 2.6e-10 40.5 0.0 3.7e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMG48875.1 - 0.00019 21.1 0.0 0.00072 19.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EMG48875.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein LRR_4 PF12799.2 EMG48876.1 - 4e-09 35.8 9.0 5.6e-07 29.0 2.0 3.7 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG48876.1 - 6.7e-08 32.1 9.6 3.4e-07 29.9 1.0 3.0 2 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EMG48876.1 - 7.3e-07 28.3 8.6 0.0086 15.9 0.3 4.6 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.1 EMG48876.1 - 5.6e-05 22.8 8.2 0.41 10.8 0.2 4.5 4 0 0 4 4 4 2 Leucine Rich repeat LRR_7 PF13504.1 EMG48876.1 - 0.0062 16.5 10.4 0.24 11.7 0.1 4.8 5 0 0 5 5 5 1 Leucine rich repeat 5_nucleotid_C PF02872.13 EMG48876.1 - 0.033 14.1 0.0 0.7 9.8 0.0 2.1 2 0 0 2 2 2 0 5'-nucleotidase, C-terminal domain HOK_GEF PF01848.11 EMG48877.1 - 0.033 13.5 0.2 0.081 12.2 0.1 1.7 1 1 1 2 2 2 0 Hok/gef family Glyco_transf_28 PF03033.15 EMG48878.1 - 1.2e-27 96.3 0.0 2.8e-27 95.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 EMG48878.1 - 8.2e-18 63.6 0.4 2.6e-12 46.0 0.1 2.7 2 0 0 2 2 2 2 GRAM domain PH PF00169.24 EMG48878.1 - 8.5e-10 38.7 0.3 1.9e-08 34.4 0.0 3.4 3 0 0 3 3 3 1 PH domain UDPGT PF00201.13 EMG48878.1 - 1.8e-07 30.1 0.0 2.9e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_2 PF08458.5 EMG48878.1 - 0.0027 17.6 0.0 0.0077 16.1 0.0 1.7 1 0 0 1 1 1 1 Plant pleckstrin homology-like region MafB19-deam PF14437.1 EMG48878.1 - 0.057 13.0 2.0 0.12 12.0 0.9 1.8 2 0 0 2 2 2 0 MafB19-like deaminase DUF3439 PF11921.3 EMG48878.1 - 0.47 10.2 5.8 1.7 8.3 4.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Fungal_trans PF04082.13 EMG48879.1 - 9.2e-19 67.3 2.5 2.7e-18 65.7 1.7 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG48879.1 - 9e-09 35.1 10.1 1.5e-08 34.3 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.16 EMG48879.1 - 0.1 12.5 0.2 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 bZIP transcription factor MCM PF00493.18 EMG48880.1 - 5.4e-136 452.7 0.3 7.5e-136 452.2 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EMG48880.1 - 2.7e-19 69.8 0.1 2.7e-19 69.8 0.1 2.9 3 1 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 EMG48880.1 - 2.4e-06 26.8 0.0 7.1e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EMG48880.1 - 0.0027 17.3 0.0 0.014 14.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EMG48880.1 - 0.0053 16.2 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain GST_N_2 PF13409.1 EMG48881.1 - 3.5e-25 87.7 0.0 9e-25 86.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMG48881.1 - 1.1e-11 44.3 0.0 2.1e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMG48881.1 - 1.8e-05 24.8 0.0 0.17 12.1 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMG48881.1 - 4.5e-05 23.3 0.0 8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMG48881.1 - 0.00086 19.7 0.0 0.0015 18.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1566 PF07603.6 EMG48881.1 - 0.057 13.1 0.0 0.16 11.7 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1566) Ras PF00071.17 EMG48882.1 - 3.6e-51 172.7 0.1 5.8e-51 172.0 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMG48882.1 - 9.2e-21 74.5 0.0 9.2e-21 74.5 0.0 2.1 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMG48882.1 - 2.2e-07 30.2 0.1 2.2e-07 30.2 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMG48882.1 - 1.5e-06 27.7 2.0 1.8e-06 27.5 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMG48882.1 - 1.8e-05 24.6 0.9 2.9e-05 23.9 0.0 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EMG48882.1 - 0.015 15.2 1.0 5 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.15 EMG48882.1 - 0.18 10.4 0.1 0.18 10.4 0.0 3.3 1 1 2 4 4 4 0 G-protein alpha subunit CobT PF06213.7 EMG48882.1 - 0.3 10.1 9.9 0.45 9.5 6.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4175 PF13779.1 EMG48882.1 - 10 3.7 19.2 13 3.3 13.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ABC_membrane PF00664.18 EMG48883.1 - 1.5e-52 178.7 8.3 1.9e-52 178.3 5.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EMG48883.1 - 2e-34 118.8 0.1 8.9e-34 116.7 0.0 2.1 2 0 0 2 2 2 1 ABC transporter ABC_ATPase PF09818.4 EMG48883.1 - 1.1e-06 27.5 0.1 1.8e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_21 PF13304.1 EMG48883.1 - 1.3e-06 28.6 2.4 0.014 15.3 0.2 3.4 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 EMG48883.1 - 4.1e-05 22.9 2.7 0.0025 17.0 1.8 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EMG48883.1 - 6.2e-05 23.0 0.0 0.00014 21.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMG48883.1 - 0.00014 21.9 0.3 0.0012 18.9 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMG48883.1 - 0.00021 22.1 0.0 0.00052 20.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EMG48883.1 - 0.00032 20.2 0.0 0.2 11.0 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_29 PF13555.1 EMG48883.1 - 0.00042 19.7 0.0 0.00091 18.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EMG48883.1 - 0.00075 18.9 0.0 0.0024 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMG48883.1 - 0.0011 18.6 0.0 0.029 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EMG48883.1 - 0.0029 17.9 0.0 0.016 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EMG48883.1 - 0.0092 15.8 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EMG48883.1 - 0.011 15.1 0.4 0.12 11.8 0.0 2.5 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF258 PF03193.11 EMG48883.1 - 0.021 14.0 0.0 0.044 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EMG48883.1 - 0.033 14.1 0.4 0.2 11.5 0.3 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EMG48883.1 - 0.098 12.3 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EMG48883.1 - 0.099 12.8 0.8 3.3 7.9 0.6 2.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad51 PF08423.6 EMG48884.1 - 1.1e-138 460.2 0.0 1.4e-138 459.9 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EMG48884.1 - 1.6e-13 50.4 0.0 2.3e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EMG48884.1 - 7.1e-10 38.4 0.0 1e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 EMG48884.1 - 7.6e-08 32.4 0.1 2.1e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 EMG48884.1 - 6.5e-07 28.7 0.0 1.3e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.1 EMG48884.1 - 0.022 14.8 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.10 EMG48884.1 - 0.053 12.3 0.1 0.11 11.4 0.1 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 EMG48884.1 - 0.1 11.3 0.0 0.24 10.2 0.0 1.5 1 0 0 1 1 1 0 PAXNEB protein mRNA_triPase PF02940.10 EMG48885.1 - 4.5e-57 193.2 8.9 7.6e-57 192.5 6.1 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain OPT PF03169.10 EMG48886.1 - 9.5e-180 599.0 44.1 1.1e-179 598.8 30.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein His_Phos_2 PF00328.17 EMG48887.1 - 6.5e-28 98.0 0.0 7.2e-28 97.9 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) OPT PF03169.10 EMG48888.1 - 2.5e-108 363.1 15.1 3.1e-108 362.8 10.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4131 PF13567.1 EMG48888.1 - 0.01 15.2 8.9 0.37 10.1 0.1 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) BofA PF07441.6 EMG48888.1 - 0.013 15.4 7.0 0.013 15.4 4.8 2.3 3 0 0 3 3 3 0 SigmaK-factor processing regulatory protein BofA DUF3093 PF11292.3 EMG48888.1 - 0.019 14.7 4.1 0.042 13.6 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) ADH_N PF08240.7 EMG48889.1 - 1.9e-25 88.7 2.5 3.2e-25 88.0 1.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMG48889.1 - 3e-19 68.8 0.0 6.3e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMG48889.1 - 7.8e-09 36.5 0.0 1.7e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EMG48889.1 - 2.1e-08 33.9 0.7 2.9e-08 33.4 0.0 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EMG48889.1 - 0.00028 20.1 0.1 0.00055 19.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EMG48889.1 - 0.0068 16.7 0.8 0.059 13.7 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EMG48889.1 - 0.012 15.2 0.8 0.066 12.8 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EMG48889.1 - 0.024 14.8 0.0 0.04 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding XdhC_C PF13478.1 EMG48889.1 - 0.031 14.5 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain DapB_N PF01113.15 EMG48889.1 - 0.032 14.1 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 EMG48889.1 - 0.11 12.5 0.1 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.15 EMG48889.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase His_Phos_1 PF00300.17 EMG48890.1 - 1.5e-17 64.1 0.0 2e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_S27 PF01599.14 EMG48890.1 - 0.09 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S27a Hist_deacetyl PF00850.14 EMG48891.1 - 2e-96 322.9 0.0 2.5e-96 322.6 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EMG48891.1 - 1.1e-50 171.5 0.6 1.8e-50 170.8 0.4 1.3 1 0 0 1 1 1 1 Arb2 domain Pkinase PF00069.20 EMG48892.1 - 1.1e-41 142.6 0.0 1.8e-41 142.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG48892.1 - 1.6e-26 92.9 0.0 2.3e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG48892.1 - 0.00051 19.0 0.0 0.00097 18.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMG48892.1 - 0.15 11.7 0.1 0.88 9.2 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Nol1_Nop2_Fmu PF01189.12 EMG48893.1 - 3.5e-17 62.7 0.0 6e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EMG48893.1 - 0.00018 21.5 0.0 0.00089 19.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EMG48893.1 - 0.046 13.7 0.0 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase OPT PF03169.10 EMG48894.1 - 2e-42 145.4 7.1 2.4e-42 145.2 4.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Mito_carr PF00153.22 EMG48895.1 - 6.6e-52 173.2 5.1 4e-22 77.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Spc97_Spc98 PF04130.8 EMG48896.1 - 1e-69 235.3 25.0 2e-69 234.3 17.4 1.5 1 0 0 1 1 1 1 Spc97 / Spc98 family Anth_synt_I_N PF04715.8 EMG48896.1 - 0.014 15.4 0.0 0.052 13.5 0.0 1.9 2 0 0 2 2 2 0 Anthranilate synthase component I, N terminal region Aminotran_1_2 PF00155.16 EMG48897.1 - 1.4e-73 247.9 0.0 2.1e-73 247.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EMG48897.1 - 3.5e-06 25.5 0.0 5.6e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EMG48897.1 - 1.3e-05 24.0 0.0 2.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EMG48897.1 - 0.024 13.6 0.3 0.15 11.0 0.2 2.0 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Abi_C PF14355.1 EMG48897.1 - 0.033 14.1 0.6 0.11 12.4 0.1 2.1 2 0 0 2 2 2 0 Abortive infection C-terminus Adeno_hexon_C PF03678.9 EMG48897.1 - 0.11 11.9 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, C-terminal domain vATP-synt_E PF01991.13 EMG48898.1 - 1.8e-58 197.0 18.6 2.2e-58 196.8 12.9 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit FliH PF02108.11 EMG48898.1 - 0.00083 19.2 0.4 0.2 11.5 0.0 2.6 2 1 0 2 2 2 2 Flagellar assembly protein FliH HK97-gp10_like PF04883.7 EMG48898.1 - 0.027 15.3 7.9 0.25 12.2 0.3 3.1 2 1 1 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component FNIP PF05725.7 EMG48899.1 - 0.33 10.9 4.9 7.8 6.5 0.0 4.2 5 1 0 5 5 5 0 FNIP Repeat CreD PF06123.7 EMG48900.1 - 0.048 12.1 0.8 0.063 11.7 0.6 1.1 1 0 0 1 1 1 0 Inner membrane protein CreD Trypan_PARP PF05887.6 EMG48900.1 - 0.17 11.7 10.9 0.34 10.7 7.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ABM PF03992.11 EMG48901.1 - 1.6e-05 24.8 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF4188 PF13826.1 EMG48901.1 - 0.0019 18.2 0.0 0.0022 18.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.1 EMG48901.1 - 0.047 12.7 0.1 0.053 12.5 0.1 1.2 1 0 0 1 1 1 0 Haem-containing dehydratase Augurin PF15187.1 EMG48901.1 - 0.066 13.0 0.2 0.086 12.7 0.1 1.3 1 1 0 1 1 1 0 Oesophageal cancer-related gene 4 HALZ PF02183.13 EMG48902.1 - 0.027 14.1 9.9 0.029 14.0 2.4 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper CCDC92 PF14916.1 EMG48902.1 - 0.035 13.7 1.0 0.035 13.7 0.7 2.5 2 0 0 2 2 2 0 Coiled-coil domain of unknown function DivIVA PF05103.8 EMG48902.1 - 0.086 12.8 4.1 1.4 8.9 0.8 2.4 2 0 0 2 2 2 0 DivIVA protein DUF904 PF06005.7 EMG48902.1 - 0.22 11.8 12.9 1.4 9.2 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Mto2_bdg PF12808.2 EMG48902.1 - 0.43 10.7 5.5 1.1 9.4 0.5 2.5 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Herpes_BLRF2 PF05812.7 EMG48902.1 - 0.48 10.2 6.9 0.17 11.6 0.2 2.3 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein IFP_35_N PF07334.8 EMG48902.1 - 0.48 10.4 6.8 0.23 11.4 2.2 2.3 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus bZIP_1 PF00170.16 EMG48902.1 - 1.1 9.3 11.6 1.9 8.4 2.0 2.9 3 0 0 3 3 3 0 bZIP transcription factor MerR_2 PF13591.1 EMG48902.1 - 4.2 7.0 5.6 0.71 9.5 0.4 2.1 2 0 0 2 2 2 0 MerR HTH family regulatory protein DivIC PF04977.10 EMG48902.1 - 6.9 6.2 8.4 13 5.3 1.2 2.3 2 0 0 2 2 2 0 Septum formation initiator Myc_N PF01056.13 EMG48903.1 - 0.0027 16.9 5.3 0.0027 16.9 3.7 2.2 2 1 0 3 3 3 1 Myc amino-terminal region U79_P34 PF03064.11 EMG48903.1 - 0.15 11.5 11.8 0.082 12.4 6.5 1.8 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Asp PF00026.18 EMG48904.1 - 9.3e-06 25.1 0.0 1.1e-05 24.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Polysacc_deac_1 PF01522.16 EMG48905.1 - 2.9e-25 88.2 0.0 5.3e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EMG48905.1 - 0.0014 17.5 0.0 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Asp PF00026.18 EMG48906.1 - 8e-25 87.7 1.6 9.5e-25 87.4 1.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMG48906.1 - 0.0014 18.6 0.2 0.038 13.9 0.2 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal RNase_PH PF01138.16 EMG48906.1 - 0.067 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 3' exoribonuclease family, domain 1 Apolipoprotein PF01442.13 EMG48907.1 - 0.0054 16.2 0.0 0.0077 15.7 0.0 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Activator-TraM PF11657.3 EMG48907.1 - 0.094 12.1 1.3 6.9 6.1 0.2 2.2 1 1 1 2 2 2 0 Transcriptional activator TraM CWC25 PF12542.3 EMG48907.1 - 0.18 12.2 2.1 0.28 11.6 1.3 1.5 1 1 0 1 1 1 0 Pre-mRNA splicing factor YtxH PF12732.2 EMG48907.1 - 0.67 10.3 5.3 0.22 11.8 0.7 2.1 1 1 1 2 2 2 0 YtxH-like protein CTP_transf_2 PF01467.21 EMG48908.1 - 2.5e-37 128.3 0.0 4.1e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase Aconitase PF00330.15 EMG48909.1 - 4.2e-191 635.4 0.2 5.5e-191 635.0 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EMG48909.1 - 7.9e-44 148.9 0.0 1.7e-43 147.8 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Cullin PF00888.17 EMG48910.1 - 2.5e-90 303.7 26.8 2.5e-90 303.7 18.6 1.8 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 EMG48910.1 - 3.4e-25 87.6 6.1 3.4e-25 87.6 4.2 2.9 3 0 0 3 3 3 1 Cullin protein neddylation domain NAP PF00956.13 EMG48911.1 - 4.3e-82 274.8 18.1 4.3e-82 274.8 12.5 2.3 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Ribosomal_S4 PF00163.14 EMG48913.1 - 1.3e-22 79.9 2.2 1.9e-22 79.4 1.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EMG48913.1 - 5.3e-11 41.7 0.0 1.4e-10 40.4 0.0 1.7 2 0 0 2 2 2 1 S4 domain DUF4315 PF14193.1 EMG48913.1 - 0.29 11.0 1.3 5.2 7.0 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4315) Ribosomal_L22e PF01776.12 EMG48913.1 - 7.4 6.6 9.0 3.3 7.7 2.0 2.7 3 0 0 3 3 3 0 Ribosomal L22e protein family ABC_membrane_2 PF06472.10 EMG48914.1 - 7.2e-87 291.0 8.3 1.1e-86 290.4 5.8 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EMG48914.1 - 2e-14 54.0 0.1 7.4e-14 52.2 0.0 2.1 2 1 0 2 2 2 1 ABC transporter AAA_23 PF13476.1 EMG48914.1 - 0.0038 17.5 1.5 0.021 15.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EMG48914.1 - 0.0061 15.8 0.2 3.2 6.9 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.12 EMG48914.1 - 0.017 14.5 0.1 2.4 7.5 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.1 EMG48914.1 - 0.046 13.2 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 EMG48914.1 - 0.055 13.2 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 EMG48914.1 - 0.22 10.6 0.0 0.39 9.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RhoGAP PF00620.22 EMG48915.1 - 1.1e-35 122.5 0.1 2.9e-35 121.1 0.1 1.8 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EMG48915.1 - 6e-29 99.9 54.9 4.2e-11 42.7 6.3 4.5 4 0 0 4 4 4 4 LIM domain DUF3620 PF12281.3 EMG48915.1 - 0.025 14.3 0.0 2.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3620) Candida_ALS_N PF11766.3 EMG48916.1 - 4.2e-85 284.6 4.3 1.1e-84 283.2 3.0 1.7 1 0 0 1 1 1 1 Cell-wall agglutinin N-terminal ligand-sugar binding BolA PF01722.13 EMG48917.1 - 4.5e-20 71.3 0.0 5.3e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein KAT11 PF08214.6 EMG48918.1 - 3.2e-73 246.8 0.4 3.5e-73 246.6 0.2 1.0 1 0 0 1 1 1 1 Histone acetylation protein Caldesmon PF02029.10 EMG48919.1 - 1.9e-06 26.5 25.8 2.6e-06 26.1 17.9 1.2 1 0 0 1 1 1 1 Caldesmon DUF913 PF06025.7 EMG48919.1 - 6.7 5.3 11.5 14 4.2 8.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Mus7 PF09462.5 EMG48920.1 - 7.6e-64 216.6 17.9 7.6e-64 216.6 12.4 3.2 3 1 0 3 3 3 1 Mus7/MMS22 family Oxidored_FMN PF00724.15 EMG48921.1 - 5.4e-88 295.2 0.0 3.3e-80 269.6 0.0 2.0 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family MFS_1 PF07690.11 EMG48922.1 - 5.3e-31 107.6 46.2 4.8e-30 104.4 14.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EMG48922.1 - 0.018 15.0 6.0 0.17 11.9 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) Ribosomal_L3 PF00297.17 EMG48923.1 - 2.4e-35 122.1 2.9 5.5e-33 114.4 2.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L3 Ribosomal_L6 PF00347.18 EMG48923.1 - 3.6e-19 69.0 1.9 1.9e-09 37.8 0.0 2.9 2 0 0 2 2 2 2 Ribosomal protein L6 CRM1_C PF08767.6 EMG48924.1 - 1.3e-122 408.7 2.4 1.3e-122 408.7 1.7 2.8 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 EMG48924.1 - 1.7e-38 131.8 6.3 1.7e-38 131.8 4.4 5.4 7 1 1 8 8 8 1 Exportin 1-like protein IBN_N PF03810.14 EMG48924.1 - 4.1e-15 55.4 0.8 4.1e-15 55.4 0.6 3.7 4 0 0 4 4 4 1 Importin-beta N-terminal domain DALR_1 PF05746.10 EMG48924.1 - 9.6e-05 22.3 3.1 0.096 12.6 0.0 4.5 4 0 0 4 4 4 2 DALR anticodon binding domain V-ATPase_H_C PF11698.3 EMG48924.1 - 0.086 12.7 6.1 16 5.4 0.1 4.5 4 0 0 4 4 4 0 V-ATPase subunit H Ldh_1_N PF00056.18 EMG48925.1 - 6.2e-42 142.7 0.1 9.6e-42 142.1 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EMG48925.1 - 1.2e-41 142.2 0.1 1.7e-41 141.8 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EMG48925.1 - 0.00021 20.1 0.0 0.0003 19.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMG48925.1 - 0.024 14.6 1.7 0.15 12.0 1.2 2.0 1 1 0 1 1 1 0 NADH(P)-binding Glyco_hydro_4 PF02056.11 EMG48925.1 - 0.041 13.2 0.2 1.7 7.9 0.0 2.8 2 1 1 3 3 3 0 Family 4 glycosyl hydrolase TnpV PF14198.1 EMG48926.1 - 0.078 12.8 0.2 0.11 12.3 0.2 1.2 1 0 0 1 1 1 0 Transposon-encoded protein TnpV ArsC PF03960.10 EMG48926.1 - 0.17 11.9 0.8 0.57 10.2 0.2 2.1 1 1 1 2 2 2 0 ArsC family Trehalase PF01204.13 EMG48927.1 - 4e-186 619.6 3.4 5.1e-186 619.2 2.3 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EMG48927.1 - 2.6e-17 61.8 0.7 5.3e-17 60.8 0.5 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Ran_BP1 PF00638.13 EMG48928.1 - 4e-53 178.6 0.9 6.5e-53 177.9 0.6 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EMG48928.1 - 0.00013 21.6 0.4 0.0018 17.9 0.3 2.2 1 1 0 1 1 1 1 WH1 domain Cellulose_synt PF03552.9 EMG48928.1 - 0.0066 14.8 0.9 0.0098 14.2 0.6 1.2 1 0 0 1 1 1 1 Cellulose synthase DUF1681 PF07933.9 EMG48928.1 - 0.35 10.4 3.2 0.1 12.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1681) polyprenyl_synt PF00348.12 EMG48929.1 - 1.7e-51 174.5 0.2 4.8e-24 84.6 0.0 3.1 3 0 0 3 3 3 3 Polyprenyl synthetase Ank_2 PF12796.2 EMG48930.1 - 1.5e-48 163.0 4.0 5.8e-16 58.6 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EMG48930.1 - 2.6e-31 105.8 0.2 2e-07 30.4 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 EMG48930.1 - 3.9e-26 88.4 3.1 1.6e-05 24.6 0.0 7.7 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 EMG48930.1 - 1.1e-25 89.5 1.4 4.1e-07 30.3 0.0 5.1 2 2 4 6 6 6 6 Ankyrin repeats (many copies) SPX PF03105.14 EMG48930.1 - 1.7e-25 90.3 24.5 3.3e-25 89.4 11.8 3.1 3 1 0 3 3 3 1 SPX domain Ank_5 PF13857.1 EMG48930.1 - 7e-23 80.1 0.5 2e-07 31.0 0.0 5.9 4 1 1 5 5 5 5 Ankyrin repeats (many copies) GDPD PF03009.12 EMG48930.1 - 0.005 16.3 0.0 0.018 14.5 0.0 1.9 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family BCDHK_Adom3 PF10436.4 EMG48931.1 - 5.9e-30 103.9 2.6 8.8e-30 103.3 1.3 1.6 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EMG48931.1 - 2e-13 50.0 0.0 5.7e-13 48.5 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EMG48931.1 - 1.5e-05 24.6 0.0 2.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EMG48931.1 - 0.021 14.5 0.0 0.061 13.1 0.0 1.7 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain DUF2013 PF09431.5 EMG48932.1 - 6.7e-41 139.3 14.8 6.7e-41 139.3 10.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) Arginosuc_synth PF00764.14 EMG48933.1 - 7e-157 522.4 0.0 8e-157 522.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 EMG48933.1 - 2.3e-06 27.3 0.0 3.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EMG48933.1 - 6.4e-05 22.3 0.0 0.0001 21.6 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EMG48933.1 - 0.00055 18.5 0.0 0.00089 17.9 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase Cas_Cmr3 PF09700.5 EMG48933.1 - 0.071 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr3) Cupin_8 PF13621.1 EMG48934.1 - 3.1e-13 49.8 0.4 5.5e-13 49.0 0.3 1.5 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EMG48934.1 - 2.5e-09 37.3 1.4 3.5e-09 36.9 0.2 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase PHD PF00628.24 EMG48934.1 - 4.9e-09 35.7 9.4 9.6e-09 34.7 6.5 1.5 1 0 0 1 1 1 1 PHD-finger Cupin_2 PF07883.6 EMG48934.1 - 0.0016 17.8 0.0 0.012 15.0 0.0 2.2 2 0 0 2 2 2 1 Cupin domain Cupin_4 PF08007.7 EMG48934.1 - 0.0021 17.3 0.0 0.0033 16.7 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_1 PF00190.17 EMG48934.1 - 0.0062 15.9 0.0 0.24 10.8 0.0 2.2 2 0 0 2 2 2 1 Cupin Prok-RING_1 PF14446.1 EMG48934.1 - 0.02 14.6 2.6 0.02 14.6 1.8 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Peptidase_S8 PF00082.17 EMG48935.1 - 2.1e-65 220.6 14.6 1.6e-40 139.0 1.8 2.1 2 0 0 2 2 2 2 Subtilase family Inhibitor_I9 PF05922.11 EMG48935.1 - 4.2e-12 46.4 0.1 2.2e-06 28.1 0.0 2.9 3 0 0 3 3 3 2 Peptidase inhibitor I9 Big_2 PF02368.13 EMG48935.1 - 0.0084 15.9 1.1 0.18 11.6 0.1 2.4 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 2) Esterase_phd PF10503.4 EMG48935.1 - 0.028 13.6 0.2 26 3.9 0.0 3.5 2 2 2 4 4 4 0 Esterase PHB depolymerase ACC_central PF08326.7 EMG48936.1 - 5.5e-266 884.2 0.0 7e-266 883.8 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EMG48936.1 - 1.6e-171 571.0 0.0 2.2e-171 570.5 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EMG48936.1 - 4.1e-50 170.0 0.0 8.6e-50 168.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EMG48936.1 - 3.2e-24 85.1 0.1 6.3e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EMG48936.1 - 3.2e-21 75.3 0.0 2.2e-20 72.6 0.0 2.4 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EMG48936.1 - 1.5e-16 59.8 0.1 3.3e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EMG48936.1 - 2.6e-10 40.3 0.0 7.8e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EMG48936.1 - 6.4e-10 38.2 0.0 3.5e-08 32.5 0.0 3.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EMG48936.1 - 0.0036 17.1 0.0 0.027 14.3 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EMG48936.1 - 0.0046 16.3 0.0 0.013 14.9 0.0 1.8 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EMG48936.1 - 0.02 14.5 0.1 3.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Biotin-lipoyl like Vhr1 PF04001.8 EMG48937.1 - 1.8e-46 155.9 4.5 3.8e-46 154.9 3.1 1.6 1 0 0 1 1 1 1 Transcription factor Vhr1 Ribonuclease_3 PF00636.21 EMG48937.1 - 0.0019 18.6 0.8 0.014 15.8 0.0 2.6 2 1 0 2 2 2 1 Ribonuclease III domain Mito_fiss_reg PF05308.6 EMG48937.1 - 0.0052 16.1 1.4 0.0052 16.1 1.0 3.4 3 1 0 3 3 3 1 Mitochondrial fission regulator CRA PF06589.6 EMG48937.1 - 0.088 12.1 0.8 0.19 11.0 0.6 1.5 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) adh_short PF00106.20 EMG48938.1 - 2.4e-22 79.6 0.0 9.6e-22 77.6 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMG48938.1 - 1.9e-12 47.4 0.1 2.7e-12 47.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMG48938.1 - 4.4e-05 23.2 0.0 0.00091 18.9 0.0 2.1 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EMG48938.1 - 0.0011 19.0 0.0 0.0025 17.8 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EMG48938.1 - 0.04 13.3 0.1 0.056 12.8 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EMG48938.1 - 0.062 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PRKCSH-like PF12999.2 EMG48940.1 - 8.8e-74 246.8 5.4 8.8e-74 246.8 3.7 2.6 3 0 0 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EMG48940.1 - 5.6e-35 120.0 0.1 5.6e-35 120.0 0.1 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Reo_sigmaC PF04582.7 EMG48940.1 - 0.012 14.8 1.2 0.012 14.8 0.9 2.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF1192 PF06698.6 EMG48940.1 - 0.034 13.9 2.4 0.049 13.4 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Syntaxin-6_N PF09177.6 EMG48940.1 - 0.06 13.7 17.9 0.23 11.8 0.5 3.8 2 1 1 3 3 3 0 Syntaxin 6, N-terminal WWE PF02825.15 EMG48940.1 - 0.081 12.3 0.5 0.24 10.8 0.1 2.0 2 0 0 2 2 2 0 WWE domain DUF3107 PF11305.3 EMG48940.1 - 0.18 11.6 0.7 5.7 6.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3107) NPV_P10 PF05531.7 EMG48940.1 - 0.25 11.5 14.7 0.22 11.7 1.6 3.8 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein ArsR PF09824.4 EMG48940.1 - 0.41 9.9 6.0 4.6 6.5 0.1 3.1 3 0 0 3 3 3 0 ArsR transcriptional regulator Prefoldin PF02996.12 EMG48940.1 - 0.6 9.7 25.0 0.11 12.1 0.7 4.7 4 1 1 5 5 5 0 Prefoldin subunit Spectrin PF00435.16 EMG48940.1 - 0.67 10.2 16.9 1.6 9.0 1.6 3.9 3 1 1 4 4 4 0 Spectrin repeat YvrJ PF12841.2 EMG48940.1 - 1.1 8.6 6.6 2.1 7.7 0.5 3.1 2 0 0 2 2 2 0 YvrJ protein family Mnd1 PF03962.10 EMG48940.1 - 1.7 8.3 22.2 2.8 7.5 2.6 3.1 2 1 0 3 3 3 0 Mnd1 family ATP-synt_B PF00430.13 EMG48940.1 - 4.9 6.9 17.5 0.099 12.4 3.3 3.3 3 2 0 3 3 3 0 ATP synthase B/B' CF(0) DUF349 PF03993.7 EMG48940.1 - 8.2 6.6 9.1 2 8.6 1.9 2.8 2 1 1 3 3 3 0 Domain of Unknown Function (DUF349) BUD22 PF09073.5 EMG48941.1 - 2.3e-96 323.5 49.3 3.1e-96 323.0 34.2 1.2 1 0 0 1 1 1 1 BUD22 TRM13 PF05206.9 EMG48942.1 - 3.7e-71 239.4 1.4 7.7e-71 238.3 1.0 1.4 1 1 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.7 EMG48942.1 - 2.2e-12 46.3 2.2 4.5e-12 45.4 1.5 1.5 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.1 EMG48942.1 - 2.6e-05 23.9 0.2 6e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMG48942.1 - 0.0057 16.2 0.3 0.011 15.3 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMG48942.1 - 0.038 14.4 0.0 0.081 13.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Glycogen_syn PF05693.8 EMG48943.1 - 0 1096.9 0.0 0 1096.7 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EMG48943.1 - 1.3e-07 31.1 0.0 6.9e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EMG48943.1 - 5.7e-07 29.8 0.0 1.2e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 EMG48943.1 - 5.6e-05 22.7 0.1 0.00013 21.5 0.0 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 EMG48943.1 - 0.0013 18.8 0.0 0.014 15.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 TCTP PF00838.12 EMG48945.1 - 1.1e-68 230.4 1.1 1.2e-68 230.2 0.8 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein gp32 PF08804.5 EMG48945.1 - 0.055 13.5 0.0 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 gp32 DNA binding protein like GerPC PF10737.4 EMG48945.1 - 0.083 12.6 0.1 0.14 11.9 0.0 1.3 1 1 0 1 1 1 0 Spore germination protein GerPC Glucan_synthase PF02364.10 EMG48946.1 - 0 1360.4 0.7 0 1360.4 0.5 1.4 2 0 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EMG48946.1 - 4.3e-37 126.6 0.1 1.3e-36 125.0 0.1 1.9 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 TPR_1 PF00515.23 EMG48947.1 - 0.00031 20.2 0.0 0.00056 19.3 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EMG48947.1 - 0.0027 17.3 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 TPR repeat TPR_16 PF13432.1 EMG48947.1 - 0.0047 17.5 0.0 0.0082 16.7 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMG48947.1 - 0.0056 16.4 0.0 0.015 15.1 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat PIN_4 PF13638.1 EMG48947.1 - 0.074 13.1 0.4 0.099 12.7 0.3 1.2 1 0 0 1 1 1 0 PIN domain TPR_8 PF13181.1 EMG48947.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat UPF0029 PF01205.14 EMG48948.1 - 6.4e-30 103.0 0.0 9.8e-30 102.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EMG48948.1 - 1.3e-09 37.9 3.0 2.5e-09 37.0 2.1 1.5 1 0 0 1 1 1 1 RWD domain WD40 PF00400.27 EMG48949.1 - 1.7e-57 189.3 11.4 1.3e-10 40.6 0.1 13.1 13 0 0 13 13 13 8 WD domain, G-beta repeat Utp12 PF04003.7 EMG48949.1 - 3.1e-26 91.4 0.3 5.3e-26 90.6 0.2 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 EMG48949.1 - 2.2e-07 30.0 2.9 0.11 11.2 0.2 4.9 2 2 1 3 3 3 3 Nup133 N terminal like Nbas_N PF15492.1 EMG48949.1 - 0.00054 19.1 0.5 0.87 8.6 0.0 4.0 4 1 0 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 EMG48949.1 - 0.013 13.8 0.6 4.3 5.5 0.0 3.9 5 0 0 5 5 5 0 Cytochrome D1 heme domain Flavoprotein PF02441.14 EMG48950.1 - 1.4e-39 134.6 0.2 4.7e-39 133.0 0.1 1.9 1 1 0 1 1 1 1 Flavoprotein Nop14 PF04147.7 EMG48950.1 - 1 7.2 52.5 2.3 6.0 36.4 1.6 1 0 0 1 1 1 0 Nop14-like family DUF2420 PF10336.4 EMG48951.1 - 0.0049 16.4 0.9 0.0049 16.4 0.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2420) TMEM171 PF15471.1 EMG48951.1 - 0.057 12.1 0.8 0.11 11.2 0.6 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 TRM PF02005.11 EMG48952.1 - 1.7e-108 362.9 0.3 1.7e-108 362.9 0.2 2.2 2 1 0 2 2 2 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_31 PF13847.1 EMG48952.1 - 2.2e-06 27.3 0.6 0.00066 19.2 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Met_10 PF02475.11 EMG48952.1 - 3.7e-05 23.3 0.0 8.3e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EMG48952.1 - 0.00036 20.5 0.0 0.00066 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMG48952.1 - 0.002 18.7 0.0 0.0045 17.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EMG48952.1 - 0.003 16.9 0.0 0.0081 15.5 0.0 1.7 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.9 EMG48952.1 - 0.0043 16.4 0.1 0.016 14.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 EMG48952.1 - 0.02 14.5 0.0 0.051 13.1 0.0 1.7 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_3 PF01596.12 EMG48952.1 - 0.022 13.7 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase MF_alpha_N PF05436.6 EMG48953.1 - 0.053 13.1 1.4 0.064 12.9 0.9 1.3 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus DUF4157 PF13699.1 EMG48953.1 - 0.46 10.6 2.7 0.52 10.4 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4157) ADP_ribosyl_GH PF03747.9 EMG48953.1 - 0.61 9.8 3.5 0.6 9.8 2.4 1.0 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Ydc2-catalyt PF09159.5 EMG48954.1 - 2.6e-33 115.6 0.5 7.4e-32 110.9 0.4 2.1 1 1 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 EMG48954.1 - 0.0029 17.4 0.6 9 6.1 0.0 3.3 2 1 0 2 2 2 2 Poxvirus A22 protein Grp1_Fun34_YaaH PF01184.14 EMG48955.1 - 2.4e-57 193.6 20.5 2.9e-57 193.3 14.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Flavi_NS4A PF01350.12 EMG48955.1 - 0.05 13.1 0.6 0.094 12.2 0.4 1.4 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A Grp1_Fun34_YaaH PF01184.14 EMG48956.1 - 9.2e-64 214.5 18.6 1.2e-63 214.2 12.9 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3589 PF12141.3 EMG48957.1 - 6.3e-117 390.8 0.6 8.3e-117 390.4 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3589) HATPase_c PF02518.21 EMG48958.1 - 1.5e-27 95.4 0.0 1.1e-21 76.6 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMG48958.1 - 1.8e-27 95.5 0.3 5.9e-27 93.9 0.2 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EMG48958.1 - 6.3e-13 48.5 0.3 1.5e-12 47.3 0.2 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 EMG48958.1 - 1.5e-05 25.0 0.5 0.00018 21.6 0.0 2.8 2 1 0 2 2 2 1 HAMP domain Mid2 PF04478.7 EMG48958.1 - 0.0021 17.4 0.2 0.0021 17.4 0.2 2.6 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor Peptidase_S24 PF00717.18 EMG48959.1 - 3.8e-09 36.0 0.0 6e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Ten1 PF12658.2 EMG48960.1 - 8.3e-12 44.9 0.0 9.5e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit WD40 PF00400.27 EMG48961.1 - 2.4e-08 33.5 0.4 8.2e-06 25.5 0.0 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat Fungal_trans PF04082.13 EMG48962.1 - 3.4e-29 101.5 0.4 3.4e-29 101.5 0.3 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG48962.1 - 7.4e-05 22.5 12.6 7.4e-05 22.5 8.7 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EMG48964.1 - 1.4e-05 25.0 0.0 0.0053 16.6 0.0 2.9 2 1 1 3 3 3 2 short chain dehydrogenase KR PF08659.5 EMG48964.1 - 0.14 11.8 0.1 0.67 9.5 0.0 2.0 2 0 0 2 2 2 0 KR domain AAA PF00004.24 EMG48965.1 - 4.1e-11 43.2 0.0 1.1e-10 41.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EMG48965.1 - 8.6e-09 34.6 1.3 9.8e-06 24.5 0.1 2.6 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EMG48965.1 - 7.9e-06 26.0 0.1 6.1e-05 23.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMG48965.1 - 6.6e-05 22.8 0.0 0.00025 20.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMG48965.1 - 0.0024 17.8 0.1 0.16 11.9 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EMG48965.1 - 0.0027 18.0 0.1 0.013 15.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EMG48965.1 - 0.0062 16.7 0.5 0.24 11.5 0.0 3.3 3 0 0 3 3 3 1 RNA helicase AAA_17 PF13207.1 EMG48965.1 - 0.0071 17.1 0.0 0.028 15.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMG48965.1 - 0.03 14.0 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain RuvB_N PF05496.7 EMG48965.1 - 0.03 13.3 0.0 0.065 12.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EMG48965.1 - 0.032 13.9 0.0 0.14 11.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EMG48965.1 - 0.037 13.2 0.0 0.086 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MFS_1 PF07690.11 EMG48966.1 - 2e-40 138.6 18.9 3.1e-40 137.9 13.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Me-amine-dh_L PF02975.9 EMG48966.1 - 0.037 13.9 0.1 0.075 13.0 0.1 1.5 1 0 0 1 1 1 0 Methylamine dehydrogenase, L chain HEAT PF02985.17 EMG48967.1 - 8.6e-05 22.3 0.1 5.8 7.2 0.0 5.4 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 EMG48967.1 - 0.0049 17.1 0.0 10 6.4 0.0 4.6 5 0 0 5 5 5 1 HEAT repeats DUF1359 PF07097.6 EMG48968.1 - 0.00014 21.8 2.8 0.00014 21.8 1.9 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1359) MRP-L46 PF11788.3 EMG48968.1 - 0.037 14.6 4.2 1.8 9.2 0.1 2.7 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 CENP-F_leu_zip PF10473.4 EMG48968.1 - 0.31 10.8 27.6 0.71 9.7 15.5 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.7 EMG48968.1 - 0.48 10.2 17.6 0.16 11.7 8.2 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Myosin_tail_1 PF01576.14 EMG48968.1 - 1 6.9 31.4 0.13 10.0 19.0 1.4 2 0 0 2 2 2 0 Myosin tail Alpha-mann_mid PF09261.6 EMG48968.1 - 1.5 9.0 4.9 1.5 9.0 1.0 2.7 1 1 0 2 2 2 0 Alpha mannosidase, middle domain DUF2937 PF11157.3 EMG48968.1 - 1.6 8.0 3.7 2.7 7.3 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) IncA PF04156.9 EMG48968.1 - 4.3 6.8 29.6 4.9 6.6 12.9 2.9 1 1 1 3 3 3 0 IncA protein NPV_P10 PF05531.7 EMG48968.1 - 6.3 7.1 12.0 2.1 8.6 2.8 3.5 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.6 EMG48968.1 - 6.4 6.7 14.2 1.5 8.8 1.1 3.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) TRAM_LAG1_CLN8 PF03798.11 EMG48969.1 - 4.9e-33 114.3 24.0 4.9e-33 114.3 16.6 2.1 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EMG48969.1 - 2.1e-22 78.4 0.4 2.1e-22 78.4 0.3 2.1 2 0 0 2 2 2 1 TRAM1-like protein FF PF01846.14 EMG48970.1 - 3.1e-22 78.2 14.1 1.6e-09 37.5 0.3 4.7 4 0 0 4 4 4 3 FF domain WW PF00397.21 EMG48970.1 - 4.4e-18 64.8 18.2 6.2e-10 38.7 4.2 2.7 2 0 0 2 2 2 2 WW domain DUF1128 PF06569.6 EMG48970.1 - 1.1 9.0 9.5 0.047 13.4 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1128) ARPC4 PF05856.7 EMG48971.1 - 1.4e-74 249.1 5.2 1.5e-74 248.9 3.6 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) DUF3832 PF12909.2 EMG48971.1 - 0.081 12.9 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3832) VHS PF00790.14 EMG48972.1 - 6.7e-33 113.2 0.5 6.7e-33 113.2 0.4 1.8 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.23 EMG48972.1 - 3.5e-14 51.9 0.0 7e-14 50.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMG48972.1 - 1.2e-13 50.4 0.6 2e-13 49.7 0.1 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EMG48972.1 - 3.7e-13 48.7 0.0 6.3e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 EMG48972.1 - 0.0033 16.8 1.7 0.0078 15.6 1.2 1.6 1 0 0 1 1 1 1 Ubiquitin interaction motif M11L PF11099.3 EMG48972.1 - 0.017 14.8 0.7 0.017 14.8 0.5 1.9 2 0 0 2 2 2 0 Apoptosis regulator M11L like CPSF100_C PF13299.1 EMG48972.1 - 0.021 15.0 1.6 0.021 15.0 1.1 2.4 2 1 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF664 PF04978.7 EMG48972.1 - 0.093 12.9 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF664) PAT1 PF09770.4 EMG48972.1 - 0.45 8.6 38.6 0.18 9.9 18.8 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 MFS_1 PF07690.11 EMG48973.1 - 5.7e-35 120.6 17.7 9e-35 120.0 12.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily ATP1G1_PLM_MAT8 PF02038.11 EMG48973.1 - 0.18 10.8 1.1 1.2 8.1 0.0 2.6 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family SRP54 PF00448.17 EMG48975.1 - 1.9e-78 262.4 1.2 5.1e-78 261.0 0.4 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EMG48975.1 - 4.1e-25 88.0 4.9 4.1e-25 88.0 3.4 3.8 5 1 0 5 5 2 1 Signal peptide binding domain SRP54_N PF02881.14 EMG48975.1 - 1e-12 47.9 2.1 1e-12 47.9 1.5 1.9 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EMG48975.1 - 1.4e-06 27.9 2.0 0.00018 20.9 0.3 3.2 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EMG48975.1 - 8.5e-06 25.5 0.5 0.00017 21.2 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EMG48975.1 - 1.8e-05 24.6 0.0 3.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 EMG48975.1 - 0.00014 21.3 0.5 0.0009 18.6 0.3 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EMG48975.1 - 0.00046 20.1 0.1 0.14 12.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EMG48975.1 - 0.0014 18.8 0.1 0.025 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EMG48975.1 - 0.0015 19.3 0.0 0.003 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 EMG48975.1 - 0.0034 16.2 0.5 0.013 14.2 0.0 2.2 2 1 0 2 2 2 1 ArgK protein APS_kinase PF01583.15 EMG48975.1 - 0.011 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase SRPRB PF09439.5 EMG48975.1 - 0.019 14.2 0.3 12 5.0 0.0 3.3 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit MipZ PF09140.6 EMG48975.1 - 0.023 13.7 0.1 0.48 9.4 0.1 2.4 1 1 0 1 1 1 0 ATPase MipZ AAA_22 PF13401.1 EMG48975.1 - 0.035 14.2 0.1 0.25 11.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain CRAL_TRIO PF00650.15 EMG48975.1 - 0.055 12.9 0.0 0.055 12.9 0.0 1.8 2 0 0 2 2 1 0 CRAL/TRIO domain Arf PF00025.16 EMG48975.1 - 0.065 12.4 0.1 0.63 9.2 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_28 PF13521.1 EMG48975.1 - 0.11 12.4 0.0 0.75 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EMG48975.1 - 0.11 11.5 1.8 0.31 10.1 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin XPC-binding PF09280.6 EMG48975.1 - 0.33 10.4 29.9 0.47 9.9 2.8 3.6 2 1 1 3 3 3 0 XPC-binding domain PAT1 PF09770.4 EMG48975.1 - 4.3 5.4 19.6 6.1 4.9 13.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIID_30kDa PF03540.8 EMG48976.1 - 1.6e-27 95.0 0.1 2.8e-27 94.2 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.8 EMG48976.1 - 0.02 14.6 0.3 5.9 6.7 0.0 2.7 3 0 0 3 3 3 0 Bromodomain associated Orbi_VP6 PF01516.11 EMG48976.1 - 0.039 13.0 0.0 0.063 12.3 0.0 1.5 1 0 0 1 1 1 0 Orbivirus helicase VP6 Pribosyl_synth PF14572.1 EMG48976.1 - 0.098 12.4 0.2 0.2 11.3 0.1 1.6 1 1 0 1 1 1 0 Phosphoribosyl synthetase-associated domain DUF908 PF06012.7 EMG48976.1 - 3.2 6.9 6.1 2.4 7.3 1.8 2.0 1 1 1 2 2 2 0 Domain of Unknown Function (DUF908) Pox_RNA_Pol_19 PF05320.7 EMG48976.1 - 10 5.8 9.9 1.8 8.3 2.7 2.5 1 1 1 3 3 3 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit HECT PF00632.20 EMG48977.1 - 1.5e-77 260.8 1.6 1.8e-77 260.5 0.1 2.0 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) F-actin_cap_A PF01267.12 EMG48978.1 - 1.3e-71 240.8 4.0 1.5e-71 240.6 2.8 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Mer2 PF09074.5 EMG48978.1 - 0.066 13.1 4.0 0.45 10.4 0.5 2.1 2 0 0 2 2 2 0 Mer2 TPR_11 PF13414.1 EMG48979.1 - 3e-35 119.6 14.4 9.5e-13 47.5 0.2 7.4 4 1 4 8 8 8 7 TPR repeat TPR_2 PF07719.12 EMG48979.1 - 3.7e-35 117.0 9.9 8.8e-07 28.3 0.0 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.23 EMG48979.1 - 2.9e-32 108.9 21.7 1.8e-07 30.4 0.1 10.2 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.1 EMG48979.1 - 2.8e-26 89.2 17.6 1.5e-07 30.7 0.1 9.8 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.1 EMG48979.1 - 9.2e-26 89.5 2.3 6.1e-05 22.8 0.1 7.1 6 1 1 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 EMG48979.1 - 4.5e-24 84.3 23.8 2.1e-17 63.0 0.9 5.4 4 1 1 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EMG48979.1 - 1.5e-16 59.0 9.5 0.01 15.9 0.3 8.7 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 EMG48979.1 - 4e-15 56.0 0.0 0.00094 19.7 0.0 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMG48979.1 - 2.6e-11 43.2 2.4 0.011 16.1 0.0 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMG48979.1 - 2.9e-09 36.7 0.0 0.82 10.4 0.0 5.4 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMG48979.1 - 4.2e-08 33.4 0.0 0.55 10.6 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMG48979.1 - 5.7e-07 29.3 0.0 0.028 14.2 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMG48979.1 - 8.5e-07 28.3 0.8 13 5.8 0.0 7.0 6 1 1 7 7 6 0 Tetratricopeptide repeat PH PF00169.24 EMG48980.1 - 1.2e-15 57.5 0.0 4.4e-15 55.7 0.0 2.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMG48980.1 - 9.7e-11 41.9 0.3 6.7e-10 39.2 0.0 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain SH3_9 PF14604.1 EMG48980.1 - 9.6e-10 37.9 0.0 1.9e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMG48980.1 - 4.5e-09 35.5 0.1 1.2e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SAM_2 PF07647.12 EMG48980.1 - 2.7e-06 27.1 0.0 6e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 EMG48980.1 - 0.00028 20.2 0.0 0.00066 19.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.1 EMG48980.1 - 0.0007 19.6 0.0 0.03 14.3 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain SAM_1 PF00536.25 EMG48980.1 - 0.014 15.5 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) MFS_1 PF07690.11 EMG48981.1 - 8.3e-15 54.3 41.0 3.2e-13 49.1 27.1 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EMG48981.1 - 1.2e-09 37.0 24.6 1.5e-09 36.6 17.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) EMP70 PF02990.11 EMG48982.1 - 4.4e-111 371.9 16.3 5.5e-111 371.5 11.3 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 SNAP PF14938.1 EMG48983.1 - 1.1e-104 349.5 4.8 1.3e-104 349.3 3.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EMG48983.1 - 1.6e-07 31.1 9.2 6.4e-05 22.8 0.5 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EMG48983.1 - 2.4e-06 26.9 1.5 0.015 15.0 0.1 4.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMG48983.1 - 4.4e-06 26.2 6.8 0.23 11.4 0.3 5.0 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 EMG48983.1 - 5.1e-06 25.8 6.9 0.65 9.7 0.2 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EMG48983.1 - 5.3e-05 22.7 11.1 0.033 13.8 2.9 3.8 1 1 2 3 3 3 3 TPR repeat Apc3 PF12895.2 EMG48983.1 - 0.0001 22.3 4.4 0.11 12.6 0.1 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EMG48983.1 - 0.0008 19.7 4.0 1.3 9.6 0.4 4.3 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMG48983.1 - 0.0033 17.9 1.2 11 6.9 0.1 4.7 1 1 4 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EMG48983.1 - 0.0072 16.9 3.2 1.2 9.9 0.1 3.6 2 1 2 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.4 EMG48983.1 - 0.0079 15.5 0.9 0.17 11.2 0.0 2.9 1 1 1 3 3 3 1 26S proteasome subunit RPN7 Foie-gras_1 PF11817.3 EMG48983.1 - 0.012 15.0 0.3 0.033 13.6 0.2 1.8 1 1 0 1 1 1 0 Foie gras liver health family 1 NSF PF02071.15 EMG48983.1 - 0.04 14.3 19.7 0.23 12.1 0.2 6.3 7 0 0 7 7 6 0 Aromatic-di-Alanine (AdAR) repeat DUF2811 PF10929.3 EMG48983.1 - 0.076 13.0 0.4 17 5.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2811) TPR_8 PF13181.1 EMG48983.1 - 0.3 10.9 13.4 0.3 10.9 0.4 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF2225 PF09986.4 EMG48983.1 - 0.94 8.8 5.5 1.5 8.2 0.2 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) ATP-synt PF00231.14 EMG48985.1 - 1.3e-70 238.0 9.1 1.5e-70 237.8 6.3 1.0 1 0 0 1 1 1 1 ATP synthase Phage_Gp14 PF10666.4 EMG48985.1 - 0.028 14.2 0.1 0.079 12.8 0.1 1.8 1 0 0 1 1 1 0 Phage protein Gp14 NDUFB10 PF10249.4 EMG48986.1 - 0.00047 20.3 0.8 0.00061 19.9 0.6 1.3 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Frag1 PF10277.4 EMG48987.1 - 5.1e-39 133.9 13.9 5.1e-39 133.9 9.6 3.2 3 1 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 EMG48987.1 - 0.00061 19.7 0.0 0.0017 18.3 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FTR1 PF03239.9 EMG48988.1 - 1.9e-72 243.8 5.6 2.5e-49 167.9 1.7 2.1 2 0 0 2 2 2 2 Iron permease FTR1 family DUF3816 PF12822.2 EMG48988.1 - 0.00011 22.2 11.6 0.022 14.6 1.5 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF3816) Pex2_Pex12 PF04757.9 EMG48988.1 - 0.021 14.2 0.0 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region Fig1 PF12351.3 EMG48988.1 - 0.041 13.7 0.3 0.041 13.7 0.2 2.3 3 0 0 3 3 3 0 Ca2+ regulator and membrane fusion protein Fig1 Tetraspannin PF00335.15 EMG48988.1 - 0.073 12.3 8.6 0.22 10.7 0.2 3.0 3 0 0 3 3 3 0 Tetraspanin family E1_DerP2_DerF2 PF02221.10 EMG48989.1 - 1.2e-24 87.0 0.4 1.6e-24 86.6 0.3 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EMG48989.1 - 0.01 15.8 0.1 0.042 13.8 0.1 2.0 1 1 0 1 1 1 0 ML-like domain DUF1091 PF06477.8 EMG48989.1 - 0.1 13.0 0.0 3.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1091) Nnf1 PF03980.9 EMG48990.1 - 3.9e-29 100.8 3.1 3.9e-29 100.8 2.2 1.8 2 0 0 2 2 2 1 Nnf1 DegS PF05384.6 EMG48990.1 - 0.044 12.9 2.0 2.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Sensor protein DegS ATP-synt_E_2 PF08112.6 EMG48990.1 - 6.5 6.8 8.6 1.3 9.1 1.0 2.4 2 0 0 2 2 2 0 ATP synthase epsilon subunit Ribosomal_S15 PF00312.17 EMG48991.1 - 1.2e-12 47.3 0.7 1.2e-12 47.3 0.5 3.1 3 0 0 3 3 3 1 Ribosomal protein S15 GrpE PF01025.14 EMG48993.1 - 4e-49 166.3 9.1 8.5e-49 165.2 6.3 1.5 1 1 0 1 1 1 1 GrpE DUF2205 PF10224.4 EMG48993.1 - 0.0028 17.1 0.8 0.0028 17.1 0.6 2.5 1 1 1 2 2 2 1 Predicted coiled-coil protein (DUF2205) DUF812 PF05667.6 EMG48993.1 - 0.019 13.4 7.0 0.023 13.2 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) OmpH PF03938.9 EMG48993.1 - 0.023 14.6 8.8 0.035 14.0 6.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ATG16 PF08614.6 EMG48993.1 - 0.071 12.9 9.9 0.094 12.5 6.8 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4201 PF13870.1 EMG48993.1 - 0.15 11.4 8.6 0.11 11.8 5.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) TerB-N PF13208.1 EMG48993.1 - 0.16 11.4 1.4 0.24 10.8 1.0 1.3 1 0 0 1 1 1 0 TerB-N APG6 PF04111.7 EMG48993.1 - 0.19 10.7 7.8 0.54 9.2 5.9 1.4 2 0 0 2 2 2 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EMG48993.1 - 0.28 8.9 3.3 0.3 8.8 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EMG48993.1 - 1.3 8.5 6.3 1.9 8.0 4.4 1.2 1 0 0 1 1 1 0 IncA protein DUF334 PF03904.8 EMG48993.1 - 1.4 8.2 5.4 2.4 7.4 3.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF334) Mnd1 PF03962.10 EMG48993.1 - 2 8.0 11.9 3 7.4 7.7 1.5 1 1 0 1 1 1 0 Mnd1 family Adeno_PIX PF03955.9 EMG48993.1 - 2.1 8.9 6.2 1.8 9.0 2.8 2.0 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF3347 PF11827.3 EMG48993.1 - 2.7 7.9 10.5 3.5 7.5 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) YlqD PF11068.3 EMG48993.1 - 6 6.9 8.1 1.4 8.9 2.7 1.9 1 1 1 2 2 2 0 YlqD protein Iso_dh PF00180.15 EMG48994.1 - 4.9e-105 351.3 0.1 8.7e-105 350.4 0.0 1.4 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Transposase_24 PF03004.9 EMG48994.1 - 0.17 11.7 0.7 0.37 10.6 0.5 1.5 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) WD40 PF00400.27 EMG48995.1 - 7.3e-15 54.1 0.7 0.00016 21.4 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat YqfQ PF14181.1 EMG48995.1 - 4.2 7.3 7.1 7 6.6 4.9 1.3 1 0 0 1 1 1 0 YqfQ-like protein Myb_DNA-binding PF00249.26 EMG48996.1 - 8.8e-09 35.2 0.0 2.3e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMG48996.1 - 0.015 15.3 0.2 0.076 13.1 0.0 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain K_oxygenase PF13434.1 EMG48996.1 - 0.07 12.0 1.1 0.16 10.8 0.2 1.9 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) PIG-H PF10181.4 EMG48997.1 - 1e-26 92.3 0.4 2e-26 91.4 0.3 1.5 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Sulfate_transp PF00916.15 EMG48999.1 - 3.4e-44 150.9 3.4 3.4e-44 150.9 2.3 1.8 2 0 0 2 2 2 1 Sulfate transporter family STAS PF01740.16 EMG48999.1 - 2.3e-13 49.5 0.5 1.6e-11 43.6 0.2 2.5 2 0 0 2 2 2 2 STAS domain cNMP_binding PF00027.24 EMG48999.1 - 0.00049 19.8 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CPSase_L_D2 PF02786.12 EMG49000.1 - 4.6e-111 369.1 0.1 6.6e-85 283.6 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EMG49000.1 - 1.5e-40 137.7 0.0 4.8e-40 136.1 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EMG49000.1 - 7.8e-39 133.3 0.0 3.9e-21 75.6 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 EMG49000.1 - 7.6e-36 122.5 0.0 8.8e-17 61.1 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 EMG49000.1 - 8.1e-26 90.5 0.0 7.4e-10 38.0 0.0 3.6 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EMG49000.1 - 2.5e-21 75.7 0.0 1.3e-09 37.6 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EMG49000.1 - 6.9e-18 64.7 0.3 3.4e-08 33.1 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EMG49000.1 - 2e-11 43.7 0.2 1.2e-06 28.1 0.1 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.14 EMG49000.1 - 3.4e-05 23.4 0.2 0.041 13.4 0.1 2.8 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 EMG49000.1 - 0.00036 19.8 0.1 0.29 10.3 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Epimerase PF01370.16 EMG49000.1 - 0.0079 15.6 0.0 0.15 11.4 0.0 2.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EMG49000.1 - 0.014 15.4 0.3 0.091 12.7 0.0 2.6 3 0 0 3 3 2 0 TrkA-N domain EAP30 PF04157.11 EMG49000.1 - 0.062 12.4 0.0 0.16 11.1 0.0 1.7 1 0 0 1 1 1 0 EAP30/Vps36 family MFS_1 PF07690.11 EMG49001.1 - 7e-14 51.3 12.8 1.9e-13 49.8 5.4 2.6 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.8 EMG49001.1 - 6.1e-05 21.3 0.1 7.7e-05 20.9 0.0 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector Candida_ALS_N PF11766.3 EMG49002.1 - 2.7e-78 262.3 0.8 3.3e-78 262.0 0.5 1.1 1 0 0 1 1 1 1 Cell-wall agglutinin N-terminal ligand-sugar binding MFS_1 PF07690.11 EMG49003.1 - 2.7e-24 85.5 6.5 3.1e-24 85.3 4.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG49003.1 - 2.5e-07 29.6 1.5 2.5e-07 29.6 1.0 1.6 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EMG49003.1 - 2.6e-05 22.6 2.4 3.6e-05 22.1 1.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EMG49003.1 - 0.00035 18.8 1.5 0.00043 18.5 1.0 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector DUF2207 PF09972.4 EMG49004.1 - 0.0079 14.8 6.5 0.011 14.4 4.5 1.4 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) Sec61_beta PF03911.11 EMG49005.1 - 1.4e-18 66.4 0.9 1.8e-18 66.0 0.6 1.1 1 0 0 1 1 1 1 Sec61beta family Podoplanin PF05808.6 EMG49005.1 - 0.17 11.4 0.9 0.29 10.6 0.6 1.5 1 1 0 1 1 1 0 Podoplanin tRNA-synt_2b PF00587.20 EMG49006.1 - 1.9e-34 118.7 0.0 3.8e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMG49006.1 - 7.7e-07 28.9 0.0 1.7e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EMG49006.1 - 0.0072 15.1 0.1 0.014 14.1 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF883 PF05957.8 EMG49007.1 - 0.091 13.1 17.9 13 6.2 2.7 5.1 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 EMG49007.1 - 0.097 12.1 12.5 0.78 9.2 1.9 2.7 2 2 0 2 2 2 0 Apolipoprotein A1/A4/E domain IncA PF04156.9 EMG49007.1 - 0.62 9.6 8.0 3.7 7.1 1.2 2.5 2 1 0 2 2 2 0 IncA protein Senescence PF06911.7 EMG49007.1 - 0.72 9.5 5.7 0.28 10.8 1.0 2.2 2 0 0 2 2 2 0 Senescence-associated protein Rsd_AlgQ PF04353.8 EMG49007.1 - 2.6 7.7 11.2 4.6 6.9 0.6 2.9 2 1 1 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ RRM_6 PF14259.1 EMG49008.1 - 5.8e-07 29.4 0.1 1.5e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMG49008.1 - 3.6e-06 26.5 0.1 7.4e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG49008.1 - 8.4e-05 22.3 0.0 0.00019 21.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MOZ_SAS PF01853.13 EMG49009.1 - 1.2e-73 246.3 1.8 1.9e-73 245.7 1.3 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-met PF12874.2 EMG49009.1 - 0.49 10.6 3.2 0.32 11.2 0.5 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EMG49009.1 - 0.59 10.5 3.1 1.5 9.3 2.2 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type PP2C PF00481.16 EMG49010.1 - 4.6e-73 245.7 0.3 9.7e-70 234.8 0.1 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Nucleoplasmin PF03066.10 EMG49010.1 - 0.012 15.1 25.9 0.084 12.3 5.7 3.3 3 0 0 3 3 3 0 Nucleoplasmin RNase_H2_suC PF08615.6 EMG49010.1 - 0.08 12.7 0.1 0.08 12.7 0.0 2.8 2 1 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Candida_ALS_N PF11766.3 EMG49011.1 - 2.6e-76 255.8 0.0 3.2e-76 255.5 0.0 1.1 1 0 0 1 1 1 1 Cell-wall agglutinin N-terminal ligand-sugar binding PTH2 PF01981.11 EMG49012.1 - 1e-43 147.7 0.0 2.5e-43 146.4 0.0 1.7 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DnaJ PF00226.26 EMG49012.1 - 1.9e-08 33.9 0.2 1.9e-08 33.9 0.1 2.3 2 1 1 3 3 3 1 DnaJ domain DUF445 PF04286.7 EMG49012.1 - 0.46 9.9 5.7 0.71 9.3 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) SRP19 PF01922.12 EMG49013.1 - 4.6e-28 97.6 0.0 8.5e-28 96.7 0.0 1.5 1 0 0 1 1 1 1 SRP19 protein Tyr-DNA_phospho PF06087.7 EMG49013.1 - 0.11 11.0 0.1 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Tyrosyl-DNA phosphodiesterase Pribosyltran PF00156.22 EMG49014.1 - 3.3e-16 59.1 0.1 6.2e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain E1-E2_ATPase PF00122.15 EMG49015.1 - 6.8e-54 182.3 0.3 1.2e-53 181.4 0.2 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMG49015.1 - 1.2e-33 116.1 9.6 1.2e-33 116.1 6.6 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMG49015.1 - 5.2e-30 105.4 0.0 4e-29 102.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMG49015.1 - 2.9e-18 66.7 0.4 6.6e-18 65.5 0.3 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMG49015.1 - 1.2e-13 50.7 0.0 2.5e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EMG49015.1 - 4.1e-11 42.1 0.0 1.4e-10 40.4 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EMG49015.1 - 0.0061 16.1 0.2 0.0061 16.1 0.1 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase PASTA PF03793.14 EMG49015.1 - 0.0079 15.8 0.0 3.7 7.2 0.0 2.8 2 0 0 2 2 2 2 PASTA domain DUF4131 PF13567.1 EMG49015.1 - 9.4 5.6 9.2 3.7 6.9 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Meth_synt_2 PF01717.13 EMG49016.1 - 6.2e-144 478.9 0.0 3.3e-137 456.8 0.0 2.9 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EMG49016.1 - 8.4e-125 416.1 0.1 4.1e-114 381.0 0.1 3.2 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain DUF3502 PF12010.3 EMG49016.1 - 0.00026 20.9 0.2 0.069 13.1 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF3502) MCP_N PF05581.7 EMG49016.1 - 0.074 13.2 0.9 0.19 11.8 0.6 1.7 1 0 0 1 1 1 0 Vibrio chemotaxis protein N terminus SEP PF08059.8 EMG49017.1 - 4.3e-26 91.0 0.0 1.3e-25 89.5 0.0 1.9 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 EMG49017.1 - 1.1e-16 60.6 0.0 2.3e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EMG49017.1 - 1.9e-09 36.9 0.5 3.1e-09 36.1 0.3 1.4 1 0 0 1 1 1 1 UBA-like domain RNB PF00773.14 EMG49018.1 - 0.00053 19.3 0.0 0.18 11.0 0.0 2.3 2 0 0 2 2 2 2 RNB domain Chorismate_bind PF00425.13 EMG49019.1 - 4.8e-89 298.0 0.0 6.9e-89 297.5 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EMG49019.1 - 6.9e-30 103.8 0.0 1.8e-27 96.0 0.0 3.1 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region DUF2312 PF10073.4 EMG49019.1 - 0.02 14.2 0.0 0.075 12.3 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) Myb_DNA-bind_6 PF13921.1 EMG49020.1 - 4.1e-13 49.2 1.3 2.2e-11 43.6 0.1 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EMG49020.1 - 3.3e-08 33.4 2.0 3.9e-06 26.8 0.2 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF4348 PF14254.1 EMG49020.1 - 0.16 11.0 1.9 0.26 10.3 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4348) Ras PF00071.17 EMG49021.1 - 2.2e-64 215.7 0.2 2.6e-64 215.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMG49021.1 - 1.1e-19 71.0 0.0 1.9e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMG49021.1 - 6.8e-16 58.0 0.1 7.8e-16 57.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMG49021.1 - 1.5e-08 34.0 0.1 1.8e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMG49021.1 - 1.8e-07 30.8 0.1 3.8e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EMG49021.1 - 2.3e-05 23.6 0.1 3.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EMG49021.1 - 9.9e-05 22.2 0.0 0.00039 20.3 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMG49021.1 - 0.00018 20.8 0.1 0.00085 18.6 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.1 EMG49021.1 - 0.0024 17.9 0.1 0.055 13.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMG49021.1 - 0.0026 17.9 0.1 0.039 14.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain CPT PF07931.7 EMG49021.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF258 PF03193.11 EMG49021.1 - 0.011 14.9 0.1 0.047 12.8 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function, DUF258 Septin PF00735.13 EMG49021.1 - 0.023 13.6 0.0 0.055 12.4 0.0 1.6 1 0 0 1 1 1 0 Septin Arch_ATPase PF01637.13 EMG49021.1 - 0.089 12.4 0.2 0.31 10.7 0.1 1.8 1 1 0 1 1 1 0 Archaeal ATPase MCM PF00493.18 EMG49021.1 - 0.11 11.2 0.0 0.19 10.4 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family ABC_tran PF00005.22 EMG49021.1 - 0.12 12.6 1.6 0.36 11.1 0.8 2.0 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EMG49021.1 - 0.14 11.6 0.1 0.14 11.6 0.1 2.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain G-alpha PF00503.15 EMG49021.1 - 0.16 10.6 2.0 3.7 6.1 0.2 2.6 1 1 1 2 2 2 0 G-protein alpha subunit ETC_C1_NDUFA5 PF04716.9 EMG49022.1 - 5.6e-25 86.6 0.1 9e-25 85.9 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region WW PF00397.21 EMG49022.1 - 1.3e-06 28.1 2.5 1.4e-06 28.0 0.3 2.3 2 0 0 2 2 2 1 WW domain Yae1_N PF09811.4 EMG49022.1 - 0.0011 18.4 0.8 0.0047 16.4 0.6 2.1 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Pro-rich PF15240.1 EMG49022.1 - 0.047 13.7 38.1 0.072 13.1 26.4 1.2 1 0 0 1 1 1 0 Proline-rich DUF605 PF04652.11 EMG49022.1 - 0.29 10.4 11.9 0.37 10.1 8.3 1.1 1 0 0 1 1 1 0 Vta1 like PXA PF02194.10 EMG49023.1 - 1.4e-45 155.1 3.3 1.4e-45 155.1 2.3 2.6 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 EMG49023.1 - 8.9e-29 99.8 4.9 1.5e-28 99.1 0.0 3.4 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.19 EMG49023.1 - 5.5e-21 74.4 2.9 5.5e-21 74.4 2.0 2.8 2 0 0 2 2 2 1 PX domain RGS PF00615.14 EMG49023.1 - 1.7e-10 40.9 0.7 1.7e-10 40.9 0.5 4.4 4 1 0 4 4 4 1 Regulator of G protein signaling domain DUF2855 PF11017.3 EMG49023.1 - 0.042 12.9 0.0 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2855) G-patch PF01585.18 EMG49024.1 - 0.0001 21.9 0.3 0.00043 20.0 0.2 2.1 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.17 EMG49025.1 - 6.3e-35 118.6 6.4 7.5e-15 54.3 0.0 5.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG49025.1 - 1.3e-29 101.9 1.7 1.4e-10 40.9 0.0 5.2 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG49025.1 - 2.5e-17 62.4 0.2 1.6e-07 31.0 0.0 3.9 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMG49025.1 - 0.015 15.0 0.0 3.5 7.4 0.0 3.7 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif DUF1438 PF07270.6 EMG49025.1 - 0.039 13.8 0.7 0.2 11.4 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1438) tRNA-synt_1 PF00133.17 EMG49026.1 - 5.5e-43 146.8 0.0 2e-33 115.3 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EMG49026.1 - 1.1e-18 67.0 1.0 1.9e-10 39.9 0.0 3.4 4 0 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EMG49026.1 - 1.9e-13 50.4 0.1 1e-12 48.0 0.0 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EMG49026.1 - 1.6e-06 27.5 0.0 3.4e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain WD40 PF00400.27 EMG49027.1 - 3.7e-49 162.9 19.4 1.4e-11 43.7 0.2 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EMG49027.1 - 2.7e-11 43.0 0.1 5.4e-11 42.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMG49027.1 - 6.5e-11 41.5 0.5 1.2e-10 40.6 0.3 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EMG49027.1 - 0.00045 18.5 2.6 0.15 10.1 0.2 3.9 3 1 1 4 4 4 1 Nucleoporin Nup120/160 Imm40 PF15582.1 EMG49027.1 - 0.01 14.5 1.6 0.017 13.8 1.1 1.2 1 0 0 1 1 1 0 Immunity protein 40 MSV199 PF10553.4 EMG49027.1 - 0.029 14.2 1.3 0.059 13.2 0.9 1.4 1 0 0 1 1 1 0 MSV199 domain PRANC PF09372.5 EMG49027.1 - 0.081 12.9 0.2 0.081 12.9 0.2 2.4 2 1 0 2 2 2 0 PRANC domain zf-C3HC PF07967.8 EMG49028.1 - 6.5e-36 123.0 0.9 2.9e-33 114.4 0.5 2.5 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 EMG49028.1 - 0.0073 16.1 6.1 0.07 12.9 0.1 3.4 3 1 0 3 3 3 2 Rsm1-like BIR PF00653.16 EMG49028.1 - 0.068 13.5 0.9 0.2 12.0 0.1 2.2 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain B3_4 PF03483.12 EMG49030.1 - 3.3e-25 88.5 0.1 5.7e-25 87.7 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EMG49030.1 - 2.2e-20 72.2 0.1 3.5e-16 58.7 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF3441 PF11923.3 EMG49031.1 - 9.2e-38 128.3 0.7 4e-37 126.2 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) FbpA PF05833.6 EMG49031.1 - 3.2e-26 91.9 28.0 3.2e-26 91.9 19.4 3.2 3 1 0 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EMG49031.1 - 8.4e-08 32.0 0.0 2.9e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Epimerase PF01370.16 EMG49032.1 - 2e-17 63.4 0.1 3.3e-17 62.7 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMG49032.1 - 6.1e-12 44.8 0.0 8.1e-12 44.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMG49032.1 - 2.1e-11 44.1 0.2 3.7e-11 43.3 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMG49032.1 - 1.2e-06 28.0 0.3 0.0031 16.8 0.1 2.2 2 0 0 2 2 2 2 NmrA-like family NAD_binding_4 PF07993.7 EMG49032.1 - 1.7e-05 23.8 0.2 0.00037 19.5 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EMG49032.1 - 0.0012 18.8 0.0 0.0073 16.2 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase DUF3110 PF11360.3 EMG49032.1 - 0.051 13.3 0.2 7 6.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3110) MtrA PF04208.9 EMG49032.1 - 0.078 12.4 0.1 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A SIR2 PF02146.12 EMG49033.1 - 9.3e-62 207.8 0.0 1.5e-61 207.2 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Cytochrome_C7 PF14522.1 EMG49033.1 - 0.025 14.2 1.0 0.054 13.1 0.7 1.5 1 0 0 1 1 1 0 Cytochrome c7 Bac_DnaA PF00308.13 EMG49033.1 - 0.065 12.8 0.2 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein DUF164 PF02591.10 EMG49033.1 - 0.12 12.1 0.8 0.24 11.2 0.5 1.4 1 0 0 1 1 1 0 Putative zinc ribbon domain FYVE_2 PF02318.11 EMG49033.1 - 1.9 8.3 5.8 0.42 10.5 0.1 2.4 2 1 1 3 3 3 0 FYVE-type zinc finger MutS_V PF00488.16 EMG49034.1 - 2e-68 230.2 0.4 4.4e-68 229.1 0.0 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 EMG49034.1 - 8.4e-30 104.0 3.6 1.5e-29 103.2 2.5 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EMG49034.1 - 1.5e-12 47.5 0.2 3.6e-12 46.2 0.1 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EMG49034.1 - 1.4e-07 31.6 0.1 3.9e-07 30.2 0.1 1.8 1 0 0 1 1 1 1 MutS domain II AAA_14 PF13173.1 EMG49034.1 - 0.001 18.9 0.3 0.2 11.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain DUF3115 PF11312.3 EMG49035.1 - 1.2e-101 339.7 0.0 1.4e-101 339.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) DUF726 PF05277.7 EMG49036.1 - 1.7e-137 457.9 1.8 2.5e-137 457.3 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Hyphal_reg_CWP PF11765.3 EMG49037.1 - 4e-90 301.9 20.4 6.6e-90 301.2 14.1 1.3 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Sec16 PF12932.2 EMG49037.1 - 0.033 14.1 9.0 0.45 10.4 0.3 3.8 3 1 0 4 4 4 0 Vesicle coat trafficking protein Sec16 mid-region CopC PF04234.7 EMG49037.1 - 0.087 13.4 19.3 1.2 9.8 0.4 4.3 1 1 1 4 4 4 0 CopC domain Qn_am_d_aII PF14930.1 EMG49037.1 - 2 8.4 8.1 16 5.4 0.1 4.5 2 2 4 6 6 6 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II Pput2613-deam PF14427.1 EMG49037.1 - 9.7 5.8 16.0 6.2 6.5 0.3 5.0 1 1 3 5 5 5 0 Pput_2613-like deaminase DEAD PF00270.24 EMG49038.1 - 3e-46 157.0 2.2 4e-46 156.5 0.0 2.3 3 1 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG49038.1 - 1.1e-24 86.0 0.0 3.5e-24 84.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EMG49038.1 - 0.11 12.6 0.1 0.11 12.6 0.1 2.3 3 0 0 3 3 3 0 AAA domain Colicin_C PF12106.3 EMG49039.1 - 3.6e-08 32.8 33.8 4.9e-05 22.8 6.2 3.9 4 0 0 4 4 4 3 Colicin C terminal ribonuclease domain ING PF12998.2 EMG49040.1 - 0.0085 16.3 2.0 0.31 11.3 0.4 2.1 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding DUF904 PF06005.7 EMG49040.1 - 0.014 15.6 7.5 3.4 8.0 0.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF904) UBN2_2 PF14227.1 EMG49040.1 - 0.025 14.1 0.4 0.07 12.6 0.2 1.9 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type DUF148 PF02520.12 EMG49040.1 - 0.042 13.6 1.6 0.54 10.0 0.2 2.5 2 2 0 2 2 2 0 Domain of unknown function DUF148 ParB PF08775.5 EMG49040.1 - 0.25 11.6 3.1 0.18 12.1 0.7 1.7 2 0 0 2 2 2 0 ParB family DUF1843 PF08898.5 EMG49040.1 - 0.27 11.2 1.3 0.38 10.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) BLOC1_2 PF10046.4 EMG49040.1 - 1.2 9.2 6.5 4.5 7.4 0.2 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Exonuc_VII_S PF02609.11 EMG49040.1 - 3.7 7.3 9.6 8.8 6.1 2.3 3.6 4 1 0 4 4 4 0 Exonuclease VII small subunit DUF2454 PF10521.4 EMG49041.1 - 1.1e-19 70.5 10.7 1.4e-17 63.6 7.4 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2454) Indigoidine_A PF04227.7 EMG49042.1 - 4.5e-102 341.2 0.2 6.4e-102 340.7 0.2 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein Chalcone PF02431.10 EMG49042.1 - 2.7e-58 196.6 0.0 6.3e-58 195.4 0.0 1.7 1 0 0 1 1 1 1 Chalcone-flavanone isomerase PfkB PF00294.19 EMG49042.1 - 7.8e-11 41.6 1.0 6.7e-05 22.1 0.0 3.2 3 1 0 3 3 3 2 pfkB family carbohydrate kinase NTP_transferase PF00483.18 EMG49043.1 - 7.7e-49 166.2 0.0 1.1e-48 165.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EMG49043.1 - 1.9e-13 49.2 8.1 1.3e-07 30.7 1.1 3.7 3 2 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EMG49043.1 - 4e-11 43.2 0.0 6.2e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EMG49043.1 - 4.9e-05 22.8 3.4 0.029 13.9 0.1 3.2 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 EMG49043.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Cytidylyltransferase MMR_HSR1 PF01926.18 EMG49045.1 - 2.1e-07 30.9 0.0 4.9e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMG49045.1 - 0.0013 18.1 0.0 0.11 11.9 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EMG49045.1 - 0.035 14.5 0.0 0.094 13.2 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 EMG49045.1 - 0.041 14.1 0.7 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 ABC transporter DUF258 PF03193.11 EMG49045.1 - 0.06 12.5 0.0 0.15 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EMG49045.1 - 0.12 11.9 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 EMG49045.1 - 0.19 11.4 0.1 0.51 10.0 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Init_tRNA_PT PF04179.7 EMG49046.1 - 2.7e-119 398.9 0.6 2.7e-119 398.9 0.4 1.7 2 0 0 2 2 2 1 Initiator tRNA phosphoribosyl transferase SPT2 PF08243.6 EMG49046.1 - 1.6e-19 70.3 20.9 1.6e-19 70.3 14.5 2.5 2 0 0 2 2 2 1 SPT2 chromatin protein FumaraseC_C PF10415.4 EMG49046.1 - 1.9e-10 40.6 0.5 5e-10 39.2 0.2 1.8 2 0 0 2 2 2 1 Fumarase C C-terminus OmpH PF03938.9 EMG49046.1 - 9.9 6.0 15.8 2.8 7.8 2.6 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TIP120 PF08623.5 EMG49047.1 - 3.3e-12 46.3 0.3 3.3e-12 46.3 0.2 3.6 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EMG49047.1 - 4.1e-07 30.1 0.0 0.0016 18.6 0.0 3.6 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.17 EMG49047.1 - 7e-06 25.6 0.1 0.0017 18.2 0.0 4.6 4 1 1 5 5 5 1 HEAT repeat UME PF08064.8 EMG49047.1 - 0.0042 17.0 0.8 0.2 11.6 0.0 3.6 3 0 0 3 3 3 1 UME (NUC010) domain HEAT_EZ PF13513.1 EMG49047.1 - 0.022 15.2 0.0 1.1 9.8 0.0 3.3 3 0 0 3 3 3 0 HEAT-like repeat CLASP_N PF12348.3 EMG49047.1 - 0.065 12.5 4.4 0.2 11.0 0.0 3.8 4 1 1 5 5 5 0 CLASP N terminal DUF2435 PF10363.4 EMG49047.1 - 0.36 10.7 6.2 0.27 11.1 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) DUF2373 PF10180.4 EMG49048.1 - 4.1e-25 87.1 0.2 7.2e-25 86.3 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Peptidase_S49_N PF08496.5 EMG49048.1 - 0.016 15.0 0.7 0.016 15.0 0.5 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF1427 PF07235.6 EMG49048.1 - 0.025 14.6 0.3 0.062 13.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1427) Casc1 PF12366.3 EMG49048.1 - 0.27 10.6 14.8 0.43 10.0 2.8 2.2 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 VSG_B PF13206.1 EMG49048.1 - 0.89 8.6 9.9 1.2 8.2 6.9 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain FliS PF02561.9 EMG49049.1 - 0.0097 15.7 0.5 0.012 15.4 0.4 1.2 1 0 0 1 1 1 1 Flagellar protein FliS DUF2924 PF11149.3 EMG49049.1 - 0.1 12.6 2.1 0.12 12.4 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) SAS4 PF15460.1 EMG49049.1 - 0.4 10.5 3.2 2 8.3 2.2 1.9 1 1 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 RasGAP_C PF03836.10 EMG49049.1 - 0.72 9.5 4.5 4.2 7.0 3.1 2.1 1 1 0 1 1 1 0 RasGAP C-terminus RmuC PF02646.11 EMG49050.1 - 0.0006 18.7 0.0 0.21 10.4 0.0 2.1 1 1 1 2 2 2 2 RmuC family Val_tRNA-synt_C PF10458.4 EMG49050.1 - 0.0096 15.9 2.4 32 4.6 0.0 4.3 1 1 2 3 3 3 0 Valyl tRNA synthetase tRNA binding arm Cast PF10174.4 EMG49050.1 - 0.012 13.6 0.0 0.015 13.4 0.0 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF3552 PF12072.3 EMG49050.1 - 0.04 13.1 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF869 PF05911.6 EMG49050.1 - 0.064 11.4 0.0 0.073 11.2 0.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) PEARLI-4 PF05278.7 EMG49050.1 - 0.075 12.3 3.5 0.47 9.7 0.7 2.0 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) BAR PF03114.13 EMG49050.1 - 0.19 11.2 0.5 2.2 7.7 0.0 2.2 1 1 1 2 2 2 0 BAR domain DUF3166 PF11365.3 EMG49050.1 - 1.5 9.2 4.8 3.3 8.2 0.4 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3166) HAD PF12710.2 EMG49051.1 - 2e-17 63.9 0.0 2.7e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMG49051.1 - 3.4e-06 27.6 0.1 4.7e-06 27.1 0.1 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMG49051.1 - 1.8e-05 25.0 0.0 4.6e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EMG49051.1 - 0.00045 19.4 1.8 0.55 9.3 0.1 3.0 3 0 0 3 3 3 2 Putative Phosphatase UMPH-1 PF05822.7 EMG49051.1 - 0.00052 19.3 0.1 0.00071 18.9 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) S_layer_N PF05123.7 EMG49051.1 - 0.015 14.9 0.3 0.023 14.3 0.2 1.2 1 0 0 1 1 1 0 S-layer like family, N-terminal region TPR_11 PF13414.1 EMG49052.1 - 4.3e-20 71.1 14.5 6.4e-07 28.9 1.7 6.5 1 1 8 9 9 9 8 TPR repeat TPR_14 PF13428.1 EMG49052.1 - 1.1e-12 47.3 0.6 0.037 14.6 0.1 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMG49052.1 - 2.8e-10 40.5 4.7 0.011 16.3 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMG49052.1 - 1.1e-09 37.5 5.9 0.00024 20.5 0.5 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMG49052.1 - 1.4e-08 34.0 10.6 0.00053 19.6 0.3 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMG49052.1 - 6.1e-06 25.9 2.3 0.019 14.7 0.5 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMG49052.1 - 1.5e-05 24.7 0.2 1.5e-05 24.7 0.2 4.7 3 2 2 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMG49052.1 - 1.8e-05 24.1 5.0 0.071 12.9 0.6 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat Borrelia_P83 PF05262.6 EMG49052.1 - 0.12 10.6 8.1 0.22 9.7 5.6 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein TPR_6 PF13174.1 EMG49052.1 - 0.14 12.7 6.7 25 5.6 0.4 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMG49052.1 - 0.3 11.3 15.2 19 5.7 0.1 6.5 5 1 1 6 6 5 0 Tetratricopeptide repeat ChAPs PF09295.5 EMG49052.1 - 0.33 9.6 7.1 1.9 7.1 0.1 3.6 3 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.1 EMG49052.1 - 3.5 6.6 16.7 0.7 8.9 0.0 3.7 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EMG49052.1 - 4.1 7.8 24.2 0.09 13.1 0.7 4.9 5 1 1 6 6 5 0 Tetratricopeptide repeat Lyase_1 PF00206.15 EMG49053.1 - 1.2e-47 162.6 0.0 1.3e-47 162.5 0.0 1.0 1 0 0 1 1 1 1 Lyase PQ-loop PF04193.9 EMG49055.1 - 9.5e-23 79.5 8.9 3e-19 68.3 0.2 2.8 2 0 0 2 2 2 2 PQ loop repeat PalH PF08733.5 EMG49055.1 - 0.052 12.3 4.5 0.12 11.1 3.1 1.8 1 1 0 1 1 1 0 PalH/RIM21 Adipogenin PF15202.1 EMG49055.1 - 1 9.2 5.9 9.9 6.1 0.0 2.7 2 1 0 2 2 2 0 Adipogenin YfhO PF09586.5 EMG49055.1 - 1.3 6.9 9.7 0.52 8.2 0.5 2.0 1 1 1 2 2 2 0 Bacterial membrane protein YfhO Rad4 PF03835.10 EMG49056.1 - 6.6e-34 116.3 6.3 1.8e-33 115.0 4.4 1.8 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EMG49056.1 - 9.6e-24 82.9 0.3 2.2e-23 81.7 0.0 1.8 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EMG49056.1 - 2.4e-22 78.2 0.1 5.4e-22 77.0 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EMG49056.1 - 0.00032 20.9 2.1 0.016 15.4 1.4 3.1 1 1 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EMG49056.1 - 0.00064 19.9 0.0 0.002 18.3 0.0 1.9 2 0 0 2 2 2 1 Transglutaminase-like superfamily Pox_MCEL PF03291.11 EMG49057.1 - 1.3e-105 352.9 0.2 1.8e-105 352.4 0.2 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_12 PF08242.7 EMG49057.1 - 2.1e-05 24.8 0.3 0.00015 22.1 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMG49057.1 - 4.7e-05 23.6 0.6 0.00016 21.9 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMG49057.1 - 0.0001 22.7 0.3 0.69 10.4 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_18 PF12847.2 EMG49057.1 - 0.00057 20.4 0.1 0.0019 18.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMG49057.1 - 0.0006 19.4 0.2 0.0037 16.8 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EMG49057.1 - 0.028 13.3 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family FSH1 PF03959.8 EMG49058.1 - 9.2e-57 191.8 0.0 1.1e-56 191.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.6 EMG49058.1 - 0.0009 19.0 0.0 0.012 15.3 0.0 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.2 EMG49058.1 - 0.0013 18.4 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Translin PF01997.11 EMG49059.1 - 9.7e-12 44.9 0.3 1.2e-11 44.5 0.2 1.3 1 0 0 1 1 1 1 Translin family DUF3885 PF13021.1 EMG49059.1 - 0.017 14.7 0.6 0.06 13.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) Suf PF05843.9 EMG49059.1 - 0.037 13.7 0.1 0.037 13.7 0.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) bZIP_1 PF00170.16 EMG49059.1 - 0.13 12.2 0.7 0.2 11.6 0.1 1.6 2 0 0 2 2 2 0 bZIP transcription factor TPR_11 PF13414.1 EMG49060.1 - 0.19 11.4 3.3 2.6 7.7 0.8 3.5 3 1 0 3 3 3 0 TPR repeat TMF_TATA_bd PF12325.3 EMG49061.1 - 3.4e-36 123.6 17.3 3.4e-36 123.6 12.0 6.3 4 3 1 5 5 5 4 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EMG49061.1 - 8.3e-15 54.3 14.1 8.3e-15 54.3 9.8 9.1 6 3 2 9 9 9 3 TATA element modulatory factor 1 DNA binding zf-C2H2_4 PF13894.1 EMG49062.1 - 0.029 14.6 0.4 0.083 13.2 0.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EMG49062.1 - 0.34 11.3 4.4 0.19 12.1 0.7 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type CAP_GLY PF01302.20 EMG49063.1 - 3.8e-17 61.7 0.1 7.4e-17 60.8 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain IncA PF04156.9 EMG49063.1 - 0.0019 17.8 30.1 0.12 11.9 8.3 2.9 1 1 1 2 2 2 2 IncA protein TMF_DNA_bd PF12329.3 EMG49063.1 - 0.0046 16.7 27.7 0.083 12.7 0.0 4.6 2 1 0 4 4 4 2 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.2 EMG49063.1 - 0.019 14.8 32.7 0.024 14.4 14.3 2.4 1 1 1 2 2 2 0 Tropomyosin like ArgK PF03308.11 EMG49063.1 - 0.019 13.7 1.1 0.033 12.9 0.8 1.3 1 0 0 1 1 1 0 ArgK protein SlyX PF04102.7 EMG49063.1 - 0.032 14.5 21.9 0.05 13.9 2.3 4.4 2 1 2 4 4 4 0 SlyX Filament PF00038.16 EMG49063.1 - 0.039 13.4 27.2 0.44 9.9 6.7 2.3 1 1 2 3 3 3 0 Intermediate filament protein AAA_13 PF13166.1 EMG49063.1 - 1.1 7.6 24.9 0.063 11.7 7.1 1.7 1 1 0 1 1 1 0 AAA domain P4Ha_N PF08336.6 EMG49063.1 - 2.8 7.7 13.0 1.1 9.0 4.6 3.1 1 1 2 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region HSP70 PF00012.15 EMG49063.1 - 3.3 5.5 14.5 0.99 7.2 7.7 1.7 1 1 1 2 2 2 0 Hsp70 protein SAB PF04382.8 EMG49063.1 - 4 7.2 9.0 1.8 8.3 0.6 3.2 3 0 0 3 3 3 0 SAB domain Syntaxin PF00804.20 EMG49063.1 - 4 7.6 21.2 0.55 10.4 2.2 2.9 1 1 0 2 2 2 0 Syntaxin Uds1 PF15456.1 EMG49063.1 - 4.2 7.3 20.5 6.5 6.7 7.2 3.6 1 1 1 2 2 2 0 Up-regulated During Septation Phage_lysis PF03245.8 EMG49063.1 - 5.2 7.0 15.8 0.25 11.3 1.1 3.1 2 1 1 3 3 3 0 Bacteriophage Rz lysis protein DUF1664 PF07889.7 EMG49063.1 - 5.4 6.8 17.9 6.7 6.5 0.4 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) KxDL PF10241.4 EMG49063.1 - 8.3 6.3 12.0 3.1 7.7 2.0 3.1 1 1 2 3 3 3 0 Uncharacterized conserved protein Abhydrolase_6 PF12697.2 EMG49064.1 - 2.9e-27 96.0 0.0 3.6e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMG49064.1 - 8.6e-17 61.4 0.0 1.4e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMG49064.1 - 6.3e-09 35.7 0.0 1.1e-08 34.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EMG49064.1 - 0.00071 18.9 0.0 0.0021 17.3 0.0 1.7 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_8 PF06259.7 EMG49064.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase IKI3 PF04762.7 EMG49067.1 - 0.046 11.5 0.1 0.057 11.2 0.0 1.1 1 0 0 1 1 1 0 IKI3 family KRTAP PF11759.3 EMG49067.1 - 5.2 7.3 24.2 8.9 6.6 16.8 1.3 1 0 0 1 1 1 0 Keratin-associated matrix Fcf2 PF08698.6 EMG49068.1 - 2.5e-37 126.8 6.4 2.5e-37 126.8 4.5 1.7 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing Integrin_alpha PF00357.15 EMG49068.1 - 1.5 8.8 5.6 3.1 7.8 0.1 3.6 2 0 0 2 2 2 0 Integrin alpha cytoplasmic region Bot1p PF12298.3 EMG49069.1 - 0.036 13.9 1.0 0.11 12.4 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic mitochondrial regulator protein PBS_linker_poly PF00427.16 EMG49069.1 - 0.66 9.6 3.2 1.2 8.7 0.0 2.7 4 0 0 4 4 4 0 Phycobilisome Linker polypeptide FBPase PF00316.15 EMG49070.1 - 6e-121 403.2 0.1 6.8e-121 403.0 0.1 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 EMG49070.1 - 0.042 13.1 0.0 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 Inositol monophosphatase family SecY PF00344.15 EMG49072.1 - 6.8e-92 308.0 11.1 9.4e-92 307.5 7.7 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EMG49072.1 - 5.4e-18 64.1 0.2 2.2e-17 62.2 0.1 2.2 1 0 0 1 1 1 1 Plug domain of Sec61p DUF2018 PF09442.5 EMG49075.1 - 0.074 13.6 0.5 0.12 12.9 0.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2018) Zn_clus PF00172.13 EMG49076.1 - 5.1e-06 26.2 5.9 7.5e-06 25.7 4.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UAA PF08449.6 EMG49077.1 - 1.2e-54 185.3 18.3 1.2e-54 185.3 12.7 4.2 3 1 0 3 3 3 1 UAA transporter family zf-DHHC PF01529.15 EMG49077.1 - 2.3e-32 111.7 23.8 2.3e-32 111.7 16.5 3.9 2 2 2 4 4 4 1 DHHC palmitoyltransferase hNIFK_binding PF12196.3 EMG49078.1 - 0.19 11.1 1.9 0.24 10.7 1.3 1.3 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK NAD_kinase PF01513.16 EMG49079.1 - 3.1e-55 186.9 0.1 4.1e-55 186.5 0.1 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DUF4411 PF14367.1 EMG49079.1 - 0.022 14.4 0.1 0.041 13.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) Hist_deacetyl PF00850.14 EMG49080.1 - 7.1e-79 265.3 0.0 1.1e-78 264.6 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain FAM181 PF15238.1 EMG49081.1 - 0.0047 17.0 0.3 0.009 16.1 0.0 1.5 1 1 1 2 2 2 1 FAM181 Nop14 PF04147.7 EMG49081.1 - 0.096 10.5 7.7 0.079 10.8 5.3 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 EMG49081.1 - 8.1 5.6 7.0 12 5.0 4.8 1.2 1 0 0 1 1 1 0 NOA36 protein Histone PF00125.19 EMG49082.1 - 3.1e-32 110.5 0.3 5.1e-32 109.8 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EMG49082.1 - 3.3e-06 27.1 0.0 5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EMG49082.1 - 0.004 17.1 0.0 0.0088 16.0 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EMG49082.1 - 0.071 12.3 0.7 0.26 10.4 0.0 1.8 1 1 1 2 2 2 0 Centromere kinetochore component CENP-T Oxidored_q6 PF01058.17 EMG49084.1 - 1e-22 80.1 0.1 1.5e-22 79.5 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit NUDIX PF00293.23 EMG49085.1 - 5.8e-15 55.1 0.0 1e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain RHH_1 PF01402.16 EMG49085.1 - 0.1 12.5 0.1 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family RINGv PF12906.2 EMG49086.1 - 0.017 15.1 1.2 0.051 13.6 0.8 1.8 1 0 0 1 1 1 0 RING-variant domain Phage_holin_3 PF05106.7 EMG49086.1 - 0.062 13.2 0.6 0.78 9.7 0.1 2.7 2 1 1 3 3 3 0 Phage holin family (Lysis protein S) FANCL_C PF11793.3 EMG49086.1 - 0.091 12.7 3.5 0.3 11.0 0.4 3.0 3 0 0 3 3 3 0 FANCL C-terminal domain TPR_11 PF13414.1 EMG49087.1 - 1.2e-53 178.6 40.0 2.6e-11 43.0 0.1 7.4 4 2 6 10 10 10 9 TPR repeat TPR_1 PF00515.23 EMG49087.1 - 1.5e-51 169.9 28.1 2e-07 30.3 0.0 11.0 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 EMG49087.1 - 2.6e-46 151.8 32.3 1e-05 25.0 0.0 10.7 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_8 PF13181.1 EMG49087.1 - 1.1e-31 106.1 19.1 0.002 17.7 0.0 10.7 8 2 3 11 11 11 8 Tetratricopeptide repeat TPR_12 PF13424.1 EMG49087.1 - 1.7e-30 104.7 33.1 1e-06 28.5 3.0 8.3 4 2 5 9 9 9 8 Tetratricopeptide repeat TPR_17 PF13431.1 EMG49087.1 - 1.2e-29 99.9 32.0 0.0015 18.5 0.1 11.5 12 1 0 12 12 11 7 Tetratricopeptide repeat TPR_16 PF13432.1 EMG49087.1 - 4.5e-29 100.4 32.2 4.7e-07 30.2 2.5 7.4 6 1 1 7 7 6 6 Tetratricopeptide repeat TPR_14 PF13428.1 EMG49087.1 - 9.4e-26 87.9 26.5 4.2e-05 23.8 0.2 10.2 4 2 6 10 10 9 7 Tetratricopeptide repeat TPR_7 PF13176.1 EMG49087.1 - 1.2e-20 71.5 12.6 0.022 14.5 0.1 9.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.1 EMG49087.1 - 1.6e-18 66.2 7.7 0.00082 19.1 0.0 6.8 3 2 4 7 7 7 7 Tetratricopeptide repeat TPR_19 PF14559.1 EMG49087.1 - 1.1e-17 64.1 37.8 6.4e-05 23.2 0.3 7.4 6 1 1 7 7 6 6 Tetratricopeptide repeat TPR_6 PF13174.1 EMG49087.1 - 2.6e-17 61.9 20.5 0.014 15.7 0.0 10.2 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_15 PF13429.1 EMG49087.1 - 5.5e-05 22.3 21.5 0.033 13.2 0.1 4.8 3 3 1 4 4 4 2 Tetratricopeptide repeat ChAPs PF09295.5 EMG49087.1 - 0.0081 14.9 0.2 0.37 9.4 0.0 3.0 3 1 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 EMG49087.1 - 9.8 6.2 19.6 1.3 9.0 0.2 6.9 9 0 0 9 9 9 0 Tetratricopeptide repeat RRM_1 PF00076.17 EMG49088.1 - 1.5e-42 143.0 0.0 5.3e-17 61.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG49088.1 - 2.5e-30 104.2 0.0 9.5e-11 41.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG49088.1 - 4.2e-25 87.3 0.0 2.6e-12 46.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMG49088.1 - 1.8e-05 24.3 0.0 0.00031 20.4 0.0 2.6 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EMG49088.1 - 0.0039 17.0 0.0 0.0039 17.0 0.0 2.5 4 0 0 4 4 4 1 RNA binding motif Nup35_RRM PF05172.8 EMG49088.1 - 0.0049 16.5 0.0 1.2 8.9 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Ribosomal_L7Ae PF01248.21 EMG49090.1 - 5.5e-25 86.7 0.7 7e-25 86.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family NTP_transf_3 PF12804.2 EMG49090.1 - 0.01 15.9 0.1 0.015 15.4 0.0 1.3 1 1 0 1 1 1 0 MobA-like NTP transferase domain DUF1269 PF06897.7 EMG49090.1 - 0.066 13.2 0.1 0.15 12.1 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1269) Rep_Org_C PF06926.6 EMG49091.1 - 0.031 14.3 0.1 0.21 11.7 0.1 2.2 2 0 0 2 2 2 0 Putative replisome organiser protein C-terminus DUF2450 PF10475.4 EMG49091.1 - 0.15 10.8 5.1 0.25 10.2 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) V_ATPase_I PF01496.14 EMG49091.1 - 0.39 8.5 5.7 0.76 7.5 3.9 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.6 EMG49091.1 - 2.1 8.2 8.8 9 6.2 0.2 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.7 EMG49091.1 - 4.3 7.6 9.0 9.7 6.5 0.6 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Cornichon PF03311.9 EMG49092.1 - 2.5e-54 182.8 10.3 2.8e-54 182.6 7.1 1.0 1 0 0 1 1 1 1 Cornichon protein Claudin_3 PF06653.6 EMG49092.1 - 0.021 14.5 6.6 0.041 13.6 4.5 1.5 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DUF1634 PF07843.6 EMG49092.1 - 0.069 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) YWFCY PF14293.1 EMG49092.1 - 0.21 11.4 0.5 0.21 11.4 0.3 2.2 3 0 0 3 3 3 0 YWFCY protein LRR_4 PF12799.2 EMG49094.1 - 1.2e-29 101.4 68.2 4.7e-08 32.4 3.0 8.9 8 1 2 10 10 10 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG49094.1 - 1.9e-20 72.3 52.9 1.5e-07 31.0 1.9 7.1 4 2 4 8 8 8 6 Leucine rich repeat LRR_1 PF00560.28 EMG49094.1 - 4.8e-07 28.9 56.5 2.7 8.3 0.3 14.9 9 5 2 11 11 11 6 Leucine Rich Repeat LRR_9 PF14580.1 EMG49094.1 - 9.7e-05 21.9 23.3 0.0012 18.3 3.8 5.1 1 1 5 6 6 6 2 Leucine-rich repeat LRR_7 PF13504.1 EMG49094.1 - 0.0001 21.9 37.3 9.3 6.9 0.0 12.0 13 1 0 13 13 13 2 Leucine rich repeat LRR_6 PF13516.1 EMG49094.1 - 0.03 14.3 49.0 0.25 11.5 0.4 11.8 9 3 3 13 13 13 0 Leucine Rich repeat DUF3272 PF11676.3 EMG49094.1 - 0.087 12.8 0.8 0.17 11.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3272) LRR_3 PF07725.7 EMG49094.1 - 0.26 11.1 2.3 46 4.0 0.0 4.3 3 0 0 3 3 3 0 Leucine Rich Repeat Zn_clus PF00172.13 EMG49095.1 - 3.2e-07 30.1 7.7 6.3e-07 29.2 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3589 PF12141.3 EMG49096.1 - 8.4e-164 545.4 5.8 1.2e-163 545.0 4.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3589) DUF4473 PF14747.1 EMG49096.1 - 0.0014 18.8 0.6 0.0041 17.3 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4473) GDI PF00996.13 EMG49097.1 - 9.8e-51 172.4 3.5 5.8e-50 169.8 0.4 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor FAD_binding_3 PF01494.14 EMG49097.1 - 0.037 13.0 0.1 0.22 10.5 0.0 2.2 2 1 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.1 EMG49097.1 - 0.066 13.2 0.0 8.8 6.4 0.0 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ENTH PF01417.15 EMG49098.1 - 1.6e-38 131.3 1.7 2.2e-38 130.9 1.2 1.2 1 0 0 1 1 1 1 ENTH domain Pap_E4 PF02711.9 EMG49098.1 - 0.37 11.6 12.9 0.5 11.2 3.3 2.7 2 0 0 2 2 2 0 E4 protein ubiquitin PF00240.18 EMG49099.1 - 9.8e-103 335.6 15.6 6.5e-34 115.1 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 EMG49099.1 - 1.8e-59 197.3 13.8 2.5e-19 68.7 0.5 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EMG49099.1 - 6.1e-19 68.0 6.5 9e-05 22.6 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EMG49099.1 - 1e-16 61.0 0.3 0.00061 19.5 0.0 3.0 3 0 0 3 3 3 3 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EMG49099.1 - 6.8e-11 42.0 1.2 0.078 12.8 0.0 3.8 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EMG49099.1 - 1.2e-10 41.4 0.7 0.076 13.2 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EMG49099.1 - 5.5e-08 32.7 0.0 0.99 9.4 0.0 3.9 3 0 0 3 3 3 3 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 EMG49099.1 - 2e-05 24.3 2.6 2.8 7.9 0.0 3.2 3 0 0 3 3 3 3 GLUT4 regulating protein TUG DUF3221 PF11518.3 EMG49099.1 - 0.00019 21.0 0.4 8.7 6.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3221) FlgD_ig PF13860.1 EMG49099.1 - 0.00044 19.9 2.4 9.2 6.0 0.0 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain Plexin_cytopl PF08337.7 EMG49099.1 - 0.00083 17.7 8.1 1.5 7.0 0.2 4.5 4 2 0 4 4 4 2 Plexin cytoplasmic RasGAP domain Methyltrans_RNA PF04452.9 EMG49099.1 - 0.00086 18.4 0.1 1.2 8.2 0.0 2.3 2 0 0 2 2 2 2 RNA methyltransferase Big_3_3 PF13750.1 EMG49099.1 - 0.011 15.2 0.0 30 3.9 0.0 3.1 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) DUF3861 PF12977.2 EMG49099.1 - 0.015 15.3 2.7 31 4.7 0.0 3.4 1 1 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_4 PF13291.1 EMG49099.1 - 0.02 15.2 0.4 68 3.9 0.0 3.2 3 0 0 3 3 3 0 ACT domain GABP-alpha PF11620.3 EMG49099.1 - 0.034 14.1 3.9 26 4.8 0.1 3.1 3 0 0 3 3 3 0 GA-binding protein alpha chain Tash_PEST PF07708.6 EMG49099.1 - 0.036 13.9 19.8 2.5 8.1 1.2 3.4 3 0 0 3 3 3 0 Tash protein PEST motif CTDII PF01556.13 EMG49099.1 - 0.052 13.4 9.2 5 7.0 0.2 3.4 1 1 2 3 3 3 0 DnaJ C terminal domain EMG1 PF03587.9 EMG49099.1 - 0.06 12.6 0.9 16 4.6 0.0 2.9 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase FERM_N PF09379.5 EMG49099.1 - 0.089 12.8 8.6 28 4.8 0.2 4.7 3 3 0 3 3 3 0 FERM N-terminal domain DUF3781 PF12636.2 EMG49099.1 - 0.29 11.1 3.6 70 3.4 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) CDC48_2 PF02933.12 EMG49099.1 - 3.3 7.4 7.5 46 3.7 0.1 3.1 3 0 0 3 3 3 0 Cell division protein 48 (CDC48), domain 2 KID PF02524.9 EMG49099.1 - 6.8 7.2 8.1 2.1e+02 2.8 0.1 4.8 3 0 0 3 3 3 0 KID repeat Ecm29 PF13001.2 EMG49100.1 - 4e-138 461.0 0.6 4e-138 461.0 0.4 2.5 3 0 0 3 3 3 1 Proteasome stabiliser HEAT PF02985.17 EMG49100.1 - 1.1e-06 28.2 12.3 0.55 10.4 0.0 8.5 9 0 0 9 9 9 4 HEAT repeat IF-2B PF01008.12 EMG49101.1 - 3.5e-77 259.1 1.5 1.7e-39 135.4 0.2 2.8 3 0 0 3 3 3 2 Initiation factor 2 subunit family DUF367 PF04034.8 EMG49101.1 - 0.057 13.0 0.0 7 6.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF367) DDRGK PF09756.4 EMG49101.1 - 0.59 9.5 15.7 1.5 8.2 10.9 1.6 1 0 0 1 1 1 0 DDRGK domain DUF2317 PF10079.4 EMG49101.1 - 6.7 5.1 15.7 21 3.5 8.5 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) E1-E2_ATPase PF00122.15 EMG49102.1 - 7.5e-18 64.4 0.4 1.3e-17 63.6 0.3 1.3 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EMG49102.1 - 4.7e-17 62.7 0.0 1.4e-16 61.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMG49102.1 - 2.2e-14 54.3 0.9 4.9e-13 49.9 0.6 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMG49102.1 - 1.5e-11 44.0 0.0 5.6e-11 42.2 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMG49102.1 - 0.0017 18.0 0.2 0.024 14.2 0.1 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMG49102.1 - 0.08 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Aldedh PF00171.17 EMG49103.1 - 3.9e-13 48.5 0.1 1.1e-12 47.0 0.1 1.6 1 1 0 1 1 1 1 Aldehyde dehydrogenase family NAD_binding_7 PF13241.1 EMG49104.1 - 1.9e-29 101.9 0.0 3.9e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EMG49104.1 - 3.7e-21 74.2 0.0 7e-21 73.3 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EMG49104.1 - 7.8e-15 53.5 0.4 1.6e-14 52.5 0.3 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ELFV_dehydrog PF00208.16 EMG49104.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF3812 PF12757.2 EMG49105.1 - 2.9e-18 66.0 2.2 2.9e-18 66.0 1.5 10.0 5 3 3 8 8 8 1 Protein of unknown function (DUF3812) Reo_sigmaC PF04582.7 EMG49105.1 - 0.15 11.1 5.3 0.46 9.6 3.6 1.8 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Romo1 PF10247.4 EMG49105.1 - 0.57 10.4 4.4 1.2 9.3 3.1 1.4 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 RRM_1 PF00076.17 EMG49106.1 - 4.2e-28 96.7 0.7 1.1e-19 69.8 0.1 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG49106.1 - 9e-25 86.4 0.2 2.7e-14 52.8 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG49106.1 - 6.1e-08 32.3 0.4 0.0015 18.3 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMG49106.1 - 0.00018 21.1 0.0 0.00033 20.3 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Kelch_3 PF13415.1 EMG49108.1 - 7e-10 38.7 0.1 1e-06 28.7 0.0 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_4 PF13418.1 EMG49108.1 - 6.7e-09 35.3 0.3 5.7e-07 29.1 0.0 3.6 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 EMG49108.1 - 4.8e-07 29.6 0.0 0.027 14.4 0.0 3.1 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 EMG49108.1 - 5.7e-07 28.9 0.1 0.00013 21.3 0.0 3.7 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 EMG49108.1 - 2.2e-06 27.5 2.5 0.00095 19.2 0.0 4.3 4 1 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 EMG49108.1 - 4.6e-06 26.1 0.0 0.00056 19.5 0.0 3.4 2 0 0 2 2 2 1 Kelch motif DUF2238 PF09997.4 EMG49108.1 - 0.14 11.5 0.1 15 4.9 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2238) JAB PF01398.16 EMG49109.1 - 5.8e-06 26.0 0.0 3e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Remorin_C PF03763.8 EMG49109.1 - 0.0056 16.1 4.0 0.0092 15.4 2.8 1.3 1 0 0 1 1 1 1 Remorin, C-terminal region COX_ARM PF06481.9 EMG49109.1 - 0.021 14.4 0.0 0.046 13.3 0.0 1.6 1 0 0 1 1 1 0 COX Aromatic Rich Motif Terpene_synth_C PF03936.11 EMG49109.1 - 0.087 12.0 3.0 0.17 11.0 2.1 1.4 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain Aldo_ket_red PF00248.16 EMG49110.1 - 2.5e-52 177.4 0.0 3e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family tRNA-synt_2 PF00152.15 EMG49111.1 - 9.1e-89 297.5 0.6 9.1e-89 297.5 0.4 1.9 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EMG49111.1 - 2.2e-10 40.2 0.1 4.5e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EMG49111.1 - 7.8e-08 31.8 0.0 0.0018 17.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EMG49111.1 - 0.0079 15.7 0.2 0.39 10.2 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) FtsJ PF01728.14 EMG49112.1 - 3e-67 226.1 0.0 3.8e-67 225.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 EMG49112.1 - 0.00021 21.8 0.0 0.011 16.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMG49112.1 - 0.00058 19.4 0.0 0.022 14.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Nol1_Nop2_Fmu PF01189.12 EMG49112.1 - 0.044 13.1 0.0 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 NOL1/NOP2/sun family zf-RING_2 PF13639.1 EMG49113.1 - 2.1e-12 46.6 2.7 3.4e-12 45.9 1.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMG49113.1 - 3.7e-08 33.3 0.8 6.5e-08 32.5 0.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EMG49113.1 - 1.1e-05 25.0 1.1 2e-05 24.1 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMG49113.1 - 1.4e-05 25.0 4.1 2.3e-05 24.3 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMG49113.1 - 0.00027 20.7 1.1 0.00042 20.1 0.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_3 PF14369.1 EMG49113.1 - 0.001 18.9 0.7 0.044 13.7 0.2 2.4 2 0 0 2 2 2 1 zinc-finger zf-RING_5 PF14634.1 EMG49113.1 - 0.0017 18.0 0.9 0.004 16.8 0.7 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMG49113.1 - 0.0019 17.8 2.2 0.004 16.7 1.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 EMG49113.1 - 0.0055 16.4 0.4 0.0078 15.9 0.3 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Rad50_zn_hook PF04423.9 EMG49113.1 - 0.0078 15.6 4.7 0.24 10.8 1.6 2.6 2 0 0 2 2 2 1 Rad50 zinc hook motif RINGv PF12906.2 EMG49113.1 - 0.042 13.8 0.6 0.075 13.0 0.4 1.4 1 0 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.1 EMG49113.1 - 0.079 12.5 4.0 1.8 8.1 0.1 2.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 U-box PF04564.10 EMG49113.1 - 0.08 12.9 0.1 1.5 8.8 0.0 2.6 2 1 1 3 3 3 0 U-box domain zf-RING_6 PF14835.1 EMG49113.1 - 0.088 12.6 3.7 0.54 10.0 2.6 2.0 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EMG49113.1 - 0.12 12.1 2.7 0.69 9.6 0.2 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EMG49113.1 - 1 9.3 5.1 6.3 6.7 3.8 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Ly49 PF08391.5 EMG49114.1 - 0.15 12.2 0.4 0.28 11.2 0.3 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region FAD-oxidase_C PF02913.14 EMG49115.1 - 5.9e-53 179.7 0.0 7.8e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EMG49115.1 - 6.5e-40 135.8 0.1 1.3e-39 134.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain DUF4356 PF14266.1 EMG49115.1 - 0.014 13.8 0.6 0.034 12.5 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4356) Yip1 PF04893.12 EMG49116.1 - 3.9e-11 42.7 20.3 6.8e-11 41.9 14.1 1.3 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 EMG49116.1 - 0.082 12.5 13.9 0.15 11.6 9.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) PGM_PMM_I PF02878.11 EMG49117.1 - 8.5e-37 125.7 0.2 9.1e-34 115.9 0.1 2.5 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EMG49117.1 - 1.3e-21 76.8 0.0 4.5e-21 75.1 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EMG49117.1 - 6.8e-13 48.6 0.0 1.2e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EMG49117.1 - 3.3e-05 23.8 0.0 0.00011 22.1 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Anp1 PF03452.9 EMG49118.1 - 1.9e-123 410.9 0.0 2.6e-123 410.4 0.0 1.2 1 0 0 1 1 1 1 Anp1 TatD_DNase PF01026.16 EMG49119.1 - 3.3e-29 101.8 0.0 4.2e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase TIM PF00121.13 EMG49120.1 - 2.2e-61 207.0 0.0 2.6e-61 206.8 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase His_Phos_1 PF00300.17 EMG49121.1 - 1.7e-33 115.9 0.0 3.6e-33 114.9 0.0 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Baculo_p74_N PF08404.5 EMG49121.1 - 0.0065 15.2 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Baculoviridae P74 N-terminal His_Phos_2 PF00328.17 EMG49121.1 - 0.025 13.9 0.1 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) Cnl2_NKP2 PF09447.5 EMG49121.1 - 0.092 12.4 1.0 0.22 11.2 0.7 1.6 1 0 0 1 1 1 0 Cnl2/NKP2 family protein SUR7 PF06687.7 EMG49122.1 - 7.2e-70 234.8 6.8 8.5e-70 234.6 4.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family Prominin PF05478.6 EMG49122.1 - 0.0054 14.3 0.2 0.021 12.3 0.0 1.9 2 0 0 2 2 2 1 Prominin Tetraspannin PF00335.15 EMG49122.1 - 0.055 12.7 15.2 0.26 10.5 3.8 3.1 3 0 0 3 3 3 0 Tetraspanin family MxiM PF11441.3 EMG49122.1 - 0.07 13.2 0.2 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Pilot protein MxiM DUF624 PF04854.9 EMG49122.1 - 0.99 9.3 8.8 0.3 10.9 2.6 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF624 Collagen PF01391.13 EMG49122.1 - 1.5 8.3 18.9 3.4 7.2 13.1 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) NIF PF03031.13 EMG49123.1 - 4.3e-27 94.7 0.1 1.4e-26 93.0 0.0 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.21 EMG49123.1 - 2.1e-05 24.5 0.0 0.0001 22.3 0.0 2.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EMG49123.1 - 0.00015 21.5 0.0 0.00058 19.6 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain NYD-SP28_assoc PF14775.1 EMG49123.1 - 0.0043 16.7 1.5 0.0095 15.6 0.0 2.2 2 0 0 2 2 2 1 Sperm tail C-terminal domain Prp19 PF08606.6 EMG49124.1 - 2.7e-30 103.8 1.7 4.8e-30 103.1 1.2 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.10 EMG49124.1 - 5.7e-07 29.4 0.1 1.7e-06 27.9 0.1 1.8 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 EMG49124.1 - 0.0072 15.8 0.0 0.019 14.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Aldo_ket_red PF00248.16 EMG49125.1 - 1.2e-53 181.7 0.0 1.5e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family SPX PF03105.14 EMG49126.1 - 5.2e-12 46.1 33.7 2.9e-08 33.8 2.5 4.4 2 1 1 3 3 3 3 SPX domain zf-C2H2 PF00096.21 EMG49127.1 - 1.8e-10 40.5 8.6 1.2e-05 25.3 0.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMG49127.1 - 1.1e-07 31.6 9.5 0.0031 17.7 2.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EMG49127.1 - 0.00034 20.7 0.8 0.026 14.7 0.3 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EMG49127.1 - 0.0019 18.4 14.3 0.0026 17.9 1.8 3.3 4 0 0 4 4 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMG49127.1 - 0.0052 16.8 0.5 0.087 12.9 0.3 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding KRTDAP PF15200.1 EMG49127.1 - 0.019 14.7 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Keratinocyte differentiation-associated Peptidase_S30 PF01577.11 EMG49127.1 - 0.027 13.8 1.0 0.039 13.3 0.7 1.2 1 0 0 1 1 1 0 Potyvirus P1 protease zf-C2H2_6 PF13912.1 EMG49127.1 - 0.039 13.8 3.6 3.7 7.5 0.7 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 EMG49127.1 - 0.13 12.3 2.7 0.6 10.2 1.5 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF2256 PF10013.4 EMG49127.1 - 0.13 12.0 1.1 5 6.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) FAM176 PF14851.1 EMG49127.1 - 3.6 7.2 7.2 6.7 6.3 0.1 2.3 2 0 0 2 2 2 0 FAM176 family zf-met2 PF12907.2 EMG49127.1 - 7.3 6.6 11.6 9 6.3 3.3 2.7 2 1 1 3 3 3 0 Zinc-binding FF PF01846.14 EMG49128.1 - 3.5e-05 23.6 0.8 8.4e-05 22.4 0.5 1.7 1 0 0 1 1 1 1 FF domain WW PF00397.21 EMG49128.1 - 0.012 15.4 0.3 0.021 14.6 0.2 1.4 1 0 0 1 1 1 0 WW domain WYL PF13280.1 EMG49128.1 - 0.024 14.5 1.5 0.042 13.7 1.0 1.4 1 0 0 1 1 1 0 WYL domain ketoacyl-synt PF00109.21 EMG49129.1 - 1.3e-60 205.0 0.3 1.6e-58 198.1 0.0 2.8 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EMG49129.1 - 4.4e-34 116.8 0.2 7.1e-34 116.2 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EMG49129.1 - 3.4e-07 29.5 0.3 3.3e-06 26.2 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Preseq_ALAS PF09029.5 EMG49129.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence Thiolase_C PF02803.13 EMG49129.1 - 0.028 13.8 1.1 0.083 12.3 0.0 2.3 2 1 1 3 3 3 0 Thiolase, C-terminal domain ADH_zinc_N PF00107.21 EMG49130.1 - 3.8e-09 36.1 0.0 1.3e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMG49130.1 - 4.2e-08 32.9 0.0 7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Sigma70_ner PF04546.8 EMG49130.1 - 9.6e-05 22.0 9.6 0.00016 21.3 6.7 1.4 1 0 0 1 1 1 1 Sigma-70, non-essential region BSP_II PF05432.6 EMG49130.1 - 0.00095 18.5 15.2 0.0015 17.8 10.5 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) DUF981 PF06168.6 EMG49130.1 - 0.003 17.3 0.6 0.0049 16.6 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF981) Cnd2 PF05786.9 EMG49130.1 - 0.014 13.9 9.8 0.024 13.1 6.8 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 SURF6 PF04935.7 EMG49130.1 - 0.02 14.2 15.9 0.018 14.3 6.9 2.1 2 0 0 2 2 2 0 Surfeit locus protein 6 RNase_H2-Ydr279 PF09468.5 EMG49130.1 - 0.029 13.5 8.9 0.013 14.6 4.2 1.7 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) Tim54 PF11711.3 EMG49130.1 - 0.038 12.5 5.8 0.06 11.9 4.0 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Nop14 PF04147.7 EMG49130.1 - 0.057 11.3 17.6 0.078 10.8 12.2 1.1 1 0 0 1 1 1 0 Nop14-like family CKAP2_C PF15297.1 EMG49130.1 - 0.074 11.8 12.7 0.16 10.7 8.8 1.4 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus DUF2413 PF10310.4 EMG49130.1 - 0.13 11.0 11.6 0.24 10.1 8.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) CobT PF06213.7 EMG49130.1 - 0.16 11.0 18.4 0.25 10.4 12.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sporozoite_P67 PF05642.6 EMG49130.1 - 0.19 9.5 12.5 0.26 9.1 8.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Hid1 PF12722.2 EMG49130.1 - 0.2 9.3 3.4 0.28 8.7 2.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RP-C_C PF11800.3 EMG49130.1 - 0.21 11.2 2.7 0.35 10.5 1.9 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF913 PF06025.7 EMG49130.1 - 0.22 10.2 2.7 0.33 9.6 1.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DDHD PF02862.12 EMG49130.1 - 0.22 11.3 6.8 0.43 10.3 4.7 1.4 1 0 0 1 1 1 0 DDHD domain DUF2201_N PF13203.1 EMG49130.1 - 0.22 10.6 1.8 0.31 10.1 1.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain TFIIF_alpha PF05793.7 EMG49130.1 - 0.24 9.7 23.0 0.37 9.1 16.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 EMG49130.1 - 0.29 9.1 14.0 0.42 8.5 9.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 EMG49130.1 - 0.3 9.5 20.3 0.45 8.9 14.1 1.2 1 0 0 1 1 1 0 Daxx Family FLO_LFY PF01698.11 EMG49130.1 - 0.32 9.7 6.9 0.49 9.1 4.8 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1510 PF07423.6 EMG49130.1 - 0.63 9.3 20.5 1.2 8.4 14.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Cellulose_synt PF03552.9 EMG49130.1 - 0.94 7.6 3.5 1.4 7.1 2.4 1.2 1 0 0 1 1 1 0 Cellulose synthase Anoctamin PF04547.7 EMG49130.1 - 0.94 8.0 2.6 1.5 7.4 1.8 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel Vfa1 PF08432.5 EMG49130.1 - 1.8 8.5 19.9 0.033 14.2 9.0 1.6 2 0 0 2 2 1 0 AAA-ATPase Vps4-associated protein 1 Myc_N PF01056.13 EMG49130.1 - 1.8 7.6 14.7 2 7.5 8.2 2.0 2 0 0 2 2 2 0 Myc amino-terminal region NPR3 PF03666.8 EMG49130.1 - 2 6.8 7.9 3.4 6.1 5.5 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RXT2_N PF08595.6 EMG49130.1 - 3.3 7.4 16.0 8.2 6.2 11.1 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal Paf1 PF03985.8 EMG49130.1 - 3.4 6.3 22.8 5.7 5.5 15.8 1.3 1 0 0 1 1 1 0 Paf1 TRAP_alpha PF03896.11 EMG49130.1 - 4.2 6.2 15.2 7.1 5.5 10.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Prog_receptor PF02161.10 EMG49130.1 - 4.6 5.9 11.5 6.4 5.4 7.9 1.1 1 0 0 1 1 1 0 Progesterone receptor Pox_Ag35 PF03286.9 EMG49130.1 - 5.2 6.5 21.7 0.25 10.8 10.7 1.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF2457 PF10446.4 EMG49130.1 - 6.9 5.2 23.7 10 4.6 16.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ycf1 PF05758.7 EMG49130.1 - 7 4.2 13.8 0.15 9.7 5.2 1.4 2 0 0 2 2 2 0 Ycf1 GOLD_2 PF13897.1 EMG49130.1 - 7.2 6.8 8.7 8.6 6.5 4.5 2.4 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking RNA_pol_3_Rpc31 PF11705.3 EMG49130.1 - 7.3 6.4 23.9 15 5.4 16.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TEX19 PF15553.1 EMG49130.1 - 9.1 6.1 7.7 16 5.3 5.4 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 RRN3 PF05327.6 EMG49130.1 - 9.2 4.2 12.5 14 3.6 8.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 F-box-like_2 PF13013.1 EMG49131.1 - 0.0055 16.3 0.8 0.039 13.6 0.4 2.6 3 1 0 3 3 3 1 F-box-like domain F-box PF00646.28 EMG49131.1 - 0.016 14.8 4.3 0.18 11.4 3.0 2.6 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 EMG49131.1 - 0.66 9.7 9.0 0.071 12.8 1.5 2.7 2 1 0 2 2 2 0 F-box-like Ribosomal_L18e PF00828.14 EMG49132.1 - 2.1e-22 79.8 0.0 3.3e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Prefoldin PF02996.12 EMG49133.1 - 8.8e-27 93.1 10.1 1.5e-26 92.3 7.0 1.4 1 0 0 1 1 1 1 Prefoldin subunit DUF1664 PF07889.7 EMG49133.1 - 0.39 10.5 3.8 4.6 7.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.7 EMG49133.1 - 2.5 8.5 8.8 0.38 11.1 1.0 2.8 3 1 0 3 3 3 0 SlyX Cortex-I_coil PF09304.5 EMG49133.1 - 2.8 8.0 12.6 0.28 11.2 2.8 2.5 1 1 1 2 2 2 0 Cortexillin I, coiled coil Syntaxin-6_N PF09177.6 EMG49133.1 - 2.8 8.3 7.2 3.2 8.2 0.7 2.5 1 1 0 2 2 2 0 Syntaxin 6, N-terminal FlxA PF14282.1 EMG49133.1 - 8 6.4 7.9 23 5.0 1.6 2.2 2 0 0 2 2 2 0 FlxA-like protein EMP24_GP25L PF01105.19 EMG49133.1 - 8.7 6.0 7.7 18 5.0 0.8 2.3 1 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD RRM_1 PF00076.17 EMG49134.1 - 4.4e-37 125.5 0.1 2.5e-18 65.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG49134.1 - 9.6e-31 105.5 0.0 6.5e-15 54.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG49134.1 - 2.4e-15 56.0 0.0 1.5e-06 27.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMG49134.1 - 0.033 13.9 0.0 8.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif ABC_trans_N PF14510.1 EMG49135.1 - 1.6e-27 95.4 0.0 2.8e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC_tran PF00005.22 EMG49135.1 - 4.1e-07 30.3 0.0 8e-07 29.4 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_25 PF13481.1 EMG49135.1 - 0.029 13.7 0.0 0.061 12.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EMG49135.1 - 0.051 13.3 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain MFS_1 PF07690.11 EMG49136.1 - 4.6e-42 143.9 31.1 7.7e-42 143.2 18.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily APG9 PF04109.11 EMG49137.1 - 2e-163 543.6 13.4 2e-163 543.6 9.3 1.7 2 0 0 2 2 2 1 Autophagy protein Apg9 DUF778 PF05608.7 EMG49137.1 - 0.13 12.1 4.0 0.17 11.8 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF778) Nop14 PF04147.7 EMG49138.1 - 2.9e-229 763.2 67.7 3.9e-132 441.9 11.1 2.7 1 1 1 2 2 2 2 Nop14-like family TCTP PF00838.12 EMG49138.1 - 0.002 18.1 0.5 0.002 18.1 0.4 2.8 3 0 0 3 3 3 1 Translationally controlled tumour protein ABC2_membrane PF01061.19 EMG49139.1 - 3.1e-82 274.8 49.3 1.5e-42 145.1 11.7 3.3 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 EMG49139.1 - 3.9e-42 142.1 0.7 6e-36 122.2 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 EMG49139.1 - 2.4e-26 92.6 0.0 4e-18 66.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 EMG49139.1 - 2.2e-05 23.7 0.0 4.8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EMG49139.1 - 8.5e-05 22.0 0.0 0.0002 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMG49139.1 - 0.00038 20.5 0.1 0.00072 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 EMG49139.1 - 0.006 16.5 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EMG49139.1 - 0.0077 16.2 0.3 0.26 11.1 0.1 2.8 1 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 EMG49139.1 - 0.0086 15.3 0.0 0.19 10.9 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EMG49139.1 - 0.0091 15.0 0.1 0.049 12.6 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EMG49139.1 - 0.011 15.2 0.1 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EMG49139.1 - 0.027 15.2 0.0 0.089 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMG49139.1 - 0.036 14.3 0.1 0.17 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EMG49139.1 - 0.061 12.7 0.2 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 EMG49139.1 - 0.073 13.3 1.5 0.15 12.4 0.2 2.0 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.1 EMG49139.1 - 0.089 12.9 0.1 0.39 10.8 0.0 2.2 2 0 0 2 2 1 0 AAA domain ABC_ATPase PF09818.4 EMG49139.1 - 0.14 10.7 0.1 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_19 PF13245.1 EMG49139.1 - 0.2 11.4 0.0 0.47 10.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EMG49139.1 - 0.21 11.2 0.5 2.7 7.6 0.1 2.5 2 0 0 2 2 2 0 NACHT domain ABC2_membrane_3 PF12698.2 EMG49139.1 - 5.3 5.9 50.1 1.6 7.6 11.3 3.3 2 2 0 2 2 2 0 ABC-2 family transporter protein Prenyltransf PF01255.14 EMG49140.1 - 0.00085 18.5 0.0 0.0031 16.6 0.0 2.0 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase PRTP PF01366.13 EMG49140.1 - 0.14 10.0 0.0 0.65 7.9 0.0 1.8 2 0 0 2 2 2 0 Herpesvirus processing and transport protein Sugar_tr PF00083.19 EMG49141.1 - 8.3e-118 393.8 26.1 1.1e-117 393.3 18.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG49141.1 - 9.9e-15 54.0 40.4 2.9e-10 39.4 8.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3249 PF11615.3 EMG49141.1 - 0.053 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3249) Ank_2 PF12796.2 EMG49142.1 - 5.7e-32 109.9 1.0 1e-12 48.1 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMG49142.1 - 4.2e-28 97.1 6.2 1.5e-08 34.8 0.0 4.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 EMG49142.1 - 1.1e-26 91.2 1.2 3.8e-06 26.4 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EMG49142.1 - 2.4e-25 87.9 0.3 2.5e-10 40.2 0.0 5.4 1 1 5 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMG49142.1 - 5.5e-21 72.5 0.5 8e-05 22.5 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat DUF3447 PF11929.3 EMG49142.1 - 5.5e-06 26.0 2.9 0.13 12.0 0.0 3.2 1 1 1 3 3 3 2 Domain of unknown function (DUF3447) Shigella_OspC PF06128.6 EMG49142.1 - 0.013 15.0 0.6 0.32 10.4 0.1 2.6 1 1 1 3 3 3 0 Shigella flexneri OspC protein MARVEL PF01284.18 EMG49143.1 - 1e-26 93.5 18.2 1.2e-26 93.2 12.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.7 EMG49143.1 - 0.003 17.1 11.8 0.021 14.4 8.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF588) Tetraspannin PF00335.15 EMG49143.1 - 0.0037 16.5 5.3 0.0037 16.5 3.7 2.0 1 1 1 2 2 2 2 Tetraspanin family 7TM-7TMR_HD PF07698.6 EMG49143.1 - 0.64 9.4 13.7 0.046 13.1 5.3 1.8 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase CytB6-F_Fe-S PF08802.5 EMG49143.1 - 3 7.9 10.5 1.9 8.5 2.8 3.0 2 1 1 3 3 3 0 Cytochrome B6-F complex Fe-S subunit Arf PF00025.16 EMG49144.1 - 6.2e-81 269.7 0.1 7e-81 269.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMG49144.1 - 2.9e-14 52.6 0.0 3.6e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EMG49144.1 - 1.8e-13 50.1 0.0 2e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EMG49144.1 - 9.9e-12 44.2 0.8 8.6e-09 34.5 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EMG49144.1 - 3.4e-11 42.7 0.0 4.1e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EMG49144.1 - 1.4e-08 35.2 0.0 1.9e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMG49144.1 - 3.9e-05 23.5 0.0 5.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EMG49144.1 - 0.0029 16.6 0.2 0.0046 16.0 0.2 1.6 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EMG49144.1 - 0.026 13.9 0.1 0.18 11.2 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EMG49144.1 - 0.077 12.8 0.1 0.13 12.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EMG49144.1 - 0.11 11.9 0.1 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CBM_5_12 PF02839.9 EMG49145.1 - 0.041 13.4 0.2 0.16 11.5 0.1 2.0 1 0 0 1 1 1 0 Carbohydrate binding domain UvrD_C PF13361.1 EMG49146.1 - 2.3e-68 231.2 0.0 4.6e-68 230.2 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EMG49146.1 - 1.4e-59 201.9 3.6 1.4e-59 201.9 2.5 2.5 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EMG49146.1 - 1.1e-10 41.6 0.0 4.9e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EMG49146.1 - 2.2e-09 36.9 0.0 8.1e-09 35.1 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_11 PF13086.1 EMG49146.1 - 0.0016 18.1 2.6 0.0055 16.3 1.8 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EMG49146.1 - 0.0087 15.6 0.3 0.045 13.3 0.0 2.3 3 1 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.13 EMG49146.1 - 0.0096 15.4 1.3 11 5.4 0.1 3.9 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 EMG49146.1 - 0.059 13.0 0.0 0.22 11.1 0.0 2.1 1 1 0 1 1 1 0 Helicase Rho_GDI PF02115.12 EMG49147.1 - 9.1e-52 175.3 0.4 1.1e-51 175.1 0.3 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor RNA_pol_Rpb8 PF03870.10 EMG49147.1 - 0.025 14.7 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb8 Big_1 PF02369.11 EMG49147.1 - 0.056 13.3 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) R3H PF01424.17 EMG49148.1 - 9e-05 22.1 0.0 0.0002 20.9 0.0 1.6 1 0 0 1 1 1 1 R3H domain CDC45 PF02724.9 EMG49148.1 - 0.028 12.4 8.3 0.053 11.5 5.8 1.5 1 0 0 1 1 1 0 CDC45-like protein SprA-related PF12118.3 EMG49148.1 - 0.54 9.5 23.0 1.2 8.4 15.9 1.7 1 0 0 1 1 1 0 SprA-related family CENP-B_dimeris PF09026.5 EMG49148.1 - 2.1 8.6 16.9 1.4 9.1 7.2 2.9 3 0 0 3 3 3 0 Centromere protein B dimerisation domain CAML PF14963.1 EMG49148.1 - 4.1 6.7 11.4 6.6 6.0 7.9 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Ufd2P_core PF10408.4 EMG49149.1 - 1.8e-199 664.0 7.7 2.4e-199 663.6 5.4 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EMG49149.1 - 1.6e-27 95.2 0.9 4.2e-27 93.9 0.6 1.8 1 0 0 1 1 1 1 U-box domain GATase_2 PF00310.16 EMG49149.1 - 0.12 11.0 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Ribosomal_L29 PF00831.18 EMG49150.1 - 3.8e-15 55.2 4.4 3.8e-15 55.2 3.1 2.2 2 0 0 2 2 2 1 Ribosomal L29 protein DUF615 PF04751.9 EMG49150.1 - 0.015 14.9 6.7 0.023 14.3 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF615) Cortex-I_coil PF09304.5 EMG49150.1 - 0.029 14.3 4.3 0.45 10.5 0.7 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil MRP-L47 PF06984.8 EMG49150.1 - 0.31 10.9 2.7 0.36 10.7 0.9 1.9 2 1 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Pox_polyA_pol_N PF12630.2 EMG49150.1 - 0.4 10.8 2.4 0.49 10.5 1.7 1.2 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain DUF2361 PF10153.4 EMG49150.1 - 1.5 9.0 11.7 2.4 8.3 1.3 2.1 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2361) RRM_1 PF00076.17 EMG49151.1 - 1.7e-56 187.7 0.1 2.4e-21 75.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG49151.1 - 3.8e-40 135.7 0.0 1.6e-15 56.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG49151.1 - 3.3e-30 103.7 0.0 3.6e-09 36.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMG49151.1 - 0.01 15.6 0.1 0.47 10.2 0.0 3.0 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 EMG49151.1 - 0.012 15.4 0.2 0.24 11.3 0.0 2.7 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_Cas2CT1978) UCH PF00443.24 EMG49152.1 - 1.6e-47 161.8 0.6 2.2e-47 161.4 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMG49152.1 - 1.8e-15 57.1 0.1 3.9e-15 56.0 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase GST_N_3 PF13417.1 EMG49153.1 - 1.4e-14 54.0 0.0 3.2e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMG49153.1 - 4.1e-12 45.9 0.0 8.1e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMG49153.1 - 5.7e-12 45.4 0.3 9.3e-12 44.7 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMG49153.1 - 6.3e-10 39.0 0.0 1.9e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMG49153.1 - 1.2e-06 28.2 0.1 2.5e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMG49153.1 - 1.6e-06 28.4 0.1 2.6e-06 27.8 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EMG49153.1 - 0.0036 17.6 0.0 0.0082 16.5 0.0 1.7 1 1 0 1 1 1 1 MetRS-N binding domain SH3_1 PF00018.23 EMG49154.1 - 4.6e-13 48.3 0.1 9e-13 47.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMG49154.1 - 1.3e-10 40.6 0.1 2.5e-10 39.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMG49154.1 - 1.5e-09 37.2 0.0 2.3e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain PAT1 PF09770.4 EMG49154.1 - 0.87 7.7 11.5 1.1 7.4 8.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_7 PF01145.20 EMG49155.1 - 2.3e-23 82.9 2.5 3.8e-23 82.3 1.8 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family E_Pc_C PF06752.7 EMG49155.1 - 0.025 14.0 0.5 0.055 12.9 0.4 1.5 1 1 0 1 1 1 0 Enhancer of Polycomb C-terminus M16C_assoc PF08367.6 EMG49156.1 - 2.3e-73 246.0 4.9 3.5e-73 245.5 3.4 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EMG49156.1 - 2e-19 70.0 0.1 6.7e-13 48.7 0.0 3.0 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EMG49156.1 - 2.4e-07 30.6 0.3 9e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Hexokinase_1 PF00349.16 EMG49156.1 - 0.034 13.4 0.1 0.17 11.2 0.0 2.2 2 1 0 2 2 2 0 Hexokinase EMP24_GP25L PF01105.19 EMG49157.1 - 1.3e-39 135.7 0.2 1.8e-39 135.3 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.7 EMG49157.1 - 0.032 12.4 1.7 0.051 11.7 1.2 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DASH_Dad2 PF08654.5 EMG49157.1 - 0.069 13.1 0.2 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 DASH complex subunit Dad2 Rad33 PF08730.5 EMG49158.1 - 1.5e-63 213.2 8.7 3.4e-63 212.1 6.0 1.6 1 0 0 1 1 1 1 Rad33 zf-C2H2 PF00096.21 EMG49158.1 - 8e-09 35.3 16.6 3.3e-06 27.1 2.1 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMG49158.1 - 2.2e-08 33.9 12.0 7.7e-08 32.2 0.6 3.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMG49158.1 - 2.9e-05 24.0 12.8 0.0042 17.3 1.3 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMG49158.1 - 0.0011 19.0 3.9 0.0077 16.3 0.3 3.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMG49158.1 - 0.0051 16.9 0.3 0.0051 16.9 0.2 2.6 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Met_10 PF02475.11 EMG49159.1 - 9.1e-08 31.9 0.0 2.3e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EMG49159.1 - 0.0027 17.7 0.0 0.0039 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMG49159.1 - 0.01 15.1 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Candida_ALS_N PF11766.3 EMG49160.1 - 9.2e-76 254.0 13.4 1.5e-75 253.3 9.3 1.3 1 0 0 1 1 1 1 Cell-wall agglutinin N-terminal ligand-sugar binding Candida_ALS PF05792.8 EMG49160.1 - 3.7e-66 218.8 343.3 5.8e-11 42.3 8.0 17.8 18 0 0 18 18 18 14 Candida agglutinin-like (ALS) zf-Nse PF11789.3 EMG49161.1 - 1.4e-18 66.1 0.1 2.9e-18 65.1 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 EMG49161.1 - 1.2e-05 25.2 0.1 2.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-RING_2 PF13639.1 EMG49161.1 - 0.0014 18.4 0.2 0.0027 17.4 0.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMG49161.1 - 0.0015 18.5 0.0 0.0057 16.7 0.0 2.0 2 1 0 2 2 2 1 RING-H2 zinc finger Eco57I PF07669.6 EMG49161.1 - 0.021 15.1 0.9 0.055 13.8 0.6 1.6 1 1 0 1 1 1 0 Eco57I restriction-modification methylase zf-RING_UBOX PF13445.1 EMG49161.1 - 0.11 12.2 0.8 0.28 10.9 0.2 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EMG49161.1 - 0.12 12.4 0.2 0.3 11.1 0.2 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMG49161.1 - 0.12 12.0 0.2 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-MYND PF01753.13 EMG49162.1 - 2.4e-08 33.6 18.3 4.7e-08 32.7 12.7 1.5 1 0 0 1 1 1 1 MYND finger TFIIA PF03153.8 EMG49162.1 - 0.025 14.4 22.2 0.29 10.9 5.0 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Sigma70_ner PF04546.8 EMG49162.1 - 0.089 12.3 7.3 0.19 11.3 5.0 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Mito_carr PF00153.22 EMG49163.1 - 2.7e-59 196.8 4.6 2e-19 69.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1049 PF06305.6 EMG49163.1 - 0.0021 17.5 0.7 0.71 9.3 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1049) TRAUB PF08164.7 EMG49164.1 - 2.6e-28 97.9 0.1 2.6e-28 97.9 0.1 3.5 4 1 0 4 4 4 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EMG49164.1 - 9.1e-24 84.0 5.0 9.1e-24 84.0 3.5 3.4 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor DUF1476 PF07345.6 EMG49164.1 - 0.0013 18.9 0.3 0.048 13.9 0.0 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1476) TFIID-18kDa PF02269.11 EMG49165.1 - 1.2e-36 124.4 1.4 1.8e-35 120.6 0.0 2.8 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit Abhydrolase_5 PF12695.2 EMG49166.1 - 1.4e-19 70.2 0.0 1.9e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMG49166.1 - 1.4e-14 54.5 0.0 6.1e-13 49.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMG49166.1 - 3.7e-08 33.1 0.1 6.2e-05 22.6 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMG49166.1 - 4.8e-06 25.9 0.0 1.6e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 EMG49166.1 - 3e-05 23.8 0.3 0.63 9.7 0.0 3.1 1 1 2 3 3 3 2 BAAT / Acyl-CoA thioester hydrolase C terminal DUF818 PF05677.7 EMG49166.1 - 0.00016 20.5 0.3 0.00024 19.9 0.2 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.11 EMG49166.1 - 0.00016 21.2 0.3 0.14 11.5 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 EMG49166.1 - 0.008 15.7 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.3 EMG49166.1 - 0.0084 15.9 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase LIP PF03583.9 EMG49166.1 - 0.014 14.6 0.6 0.033 13.4 0.0 1.8 1 1 1 2 2 2 0 Secretory lipase Peptidase_S15 PF02129.13 EMG49166.1 - 0.04 13.3 0.0 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 EMG49166.1 - 0.048 12.1 0.2 1.7 7.0 0.0 2.6 2 1 1 3 3 3 0 Acetyl xylan esterase (AXE1) IF4E PF01652.13 EMG49167.1 - 4.3e-60 202.0 2.7 5.2e-60 201.7 1.9 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Baculo_LEF-11 PF06385.7 EMG49167.1 - 0.014 15.5 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Baculovirus LEF-11 protein Med2 PF11214.3 EMG49169.1 - 4.3e-35 119.8 2.2 4.3e-35 119.8 1.5 4.7 2 1 1 3 3 3 1 Mediator complex subunit 2 SprA-related PF12118.3 EMG49169.1 - 0.73 9.1 32.4 0.26 10.5 17.2 2.2 2 0 0 2 2 2 0 SprA-related family MAP7 PF05672.6 EMG49169.1 - 0.85 8.9 53.7 1.9 7.8 37.2 1.5 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Asp-B-Hydro_N PF05279.6 EMG49169.1 - 6.3 6.5 30.4 1.7 8.4 18.7 1.7 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Rad21_Rec8_N PF04825.8 EMG49170.1 - 8.9e-32 109.3 0.1 1.8e-31 108.3 0.1 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EMG49170.1 - 1.1e-07 30.8 0.0 2.7e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein WD40 PF00400.27 EMG49171.1 - 0.018 14.9 1.1 12 5.9 0.1 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat WD40 PF00400.27 EMG49172.1 - 5e-16 57.8 1.9 1.9e-08 33.8 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat zf-RING_2 PF13639.1 EMG49172.1 - 0.00077 19.2 5.1 0.00077 19.2 3.6 2.5 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EMG49172.1 - 0.0031 17.5 7.3 0.014 15.4 5.0 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMG49172.1 - 0.037 14.0 12.1 0.046 13.7 4.2 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) BBS2_Mid PF14783.1 EMG49172.1 - 0.069 12.9 0.0 0.53 10.0 0.0 2.5 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region zf-C3HC4 PF00097.20 EMG49172.1 - 0.23 11.1 6.0 2.1 8.0 4.2 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EMG49172.1 - 0.53 10.3 6.4 1.9 8.5 4.4 2.0 1 1 0 1 1 1 0 RING-like domain C1_1 PF00130.17 EMG49172.1 - 1.6 8.4 10.0 2.3 8.0 1.6 2.6 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DER1 PF04511.10 EMG49173.1 - 1.1e-23 83.7 12.0 5.5e-22 78.2 8.3 2.1 1 1 0 1 1 1 1 Der1-like family CR6_interact PF10147.4 EMG49174.1 - 0.017 14.4 1.8 0.025 13.9 1.2 1.3 1 1 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 ADH_zinc_N PF00107.21 EMG49175.1 - 7.6e-29 99.8 0.1 1.3e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMG49175.1 - 4.3e-26 90.8 0.1 1.7e-25 88.9 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Pyr_redox PF00070.22 EMG49175.1 - 0.00036 20.8 0.2 0.051 13.9 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EMG49175.1 - 0.0068 15.8 0.1 0.01 15.1 0.1 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 EMG49175.1 - 0.02 14.4 0.6 0.038 13.5 0.2 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_11 PF08241.7 EMG49175.1 - 0.02 15.3 0.0 0.035 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain HI0933_like PF03486.9 EMG49175.1 - 0.029 12.8 0.8 0.04 12.3 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 EMG49175.1 - 0.051 12.6 0.0 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain PALP PF00291.20 EMG49175.1 - 0.064 12.4 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme ATP-synt_DE_N PF02823.11 EMG49176.1 - 3.9e-22 77.7 0.0 5.8e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain RNA_pol_Rpb1_1 PF04997.7 EMG49177.1 - 5.2e-119 397.4 0.0 1.1e-118 396.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EMG49177.1 - 9.3e-110 366.2 0.1 1.5e-109 365.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EMG49177.1 - 9.7e-71 237.0 0.0 2.7e-70 235.6 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EMG49177.1 - 1.4e-65 220.5 3.1 4.6e-65 218.8 0.1 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EMG49177.1 - 1.5e-49 167.7 0.0 3.4e-49 166.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EMG49177.1 - 2.9e-49 166.2 3.7 2.9e-49 166.2 2.6 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EMG49177.1 - 4.2e-38 129.3 0.1 1.1e-37 128.0 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EMG49177.1 - 6.4e-14 50.7 295.4 0.029 14.4 7.7 15.6 11 1 0 14 14 14 12 RNA polymerase Rpb1 C-terminal repeat PIF1 PF05970.9 EMG49178.1 - 9.3e-54 182.7 3.6 5.2e-51 173.7 2.5 2.5 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EMG49178.1 - 2.4e-17 63.1 0.0 5.1e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EMG49178.1 - 3e-07 29.7 0.8 5.4e-07 28.9 0.0 1.9 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EMG49178.1 - 1.2e-06 28.7 0.0 2.6e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMG49178.1 - 0.00057 19.5 0.1 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain TrwB_AAD_bind PF10412.4 EMG49178.1 - 0.00079 18.1 0.3 0.025 13.2 0.0 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain T2SE PF00437.15 EMG49178.1 - 0.0047 15.8 0.0 0.0088 14.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.11 EMG49178.1 - 0.011 14.9 0.3 0.081 12.1 0.0 2.5 3 0 0 3 3 3 0 PhoH-like protein AAA_16 PF13191.1 EMG49178.1 - 0.027 14.4 0.0 0.053 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF3472 PF11958.3 EMG49178.1 - 0.047 14.0 1.1 0.099 12.9 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3472) Helicase_RecD PF05127.9 EMG49178.1 - 0.064 12.8 0.1 0.33 10.5 0.1 2.2 1 1 0 1 1 1 0 Helicase IstB_IS21 PF01695.12 EMG49178.1 - 0.11 11.9 0.0 2.5 7.4 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_tran PF00005.22 EMG49178.1 - 0.15 12.3 2.3 0.3 11.3 0.0 2.5 2 1 1 3 3 3 0 ABC transporter DUF1777 PF08648.7 EMG49178.1 - 0.18 11.5 3.4 0.28 10.9 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) SAICAR_synt PF01259.13 EMG49179.1 - 1.6e-99 332.0 0.1 1.9e-99 331.8 0.1 1.0 1 0 0 1 1 1 1 SAICAR synthetase Phage_XkdX PF09693.5 EMG49179.1 - 0.061 12.8 0.1 0.21 11.1 0.1 2.0 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) BAR PF03114.13 EMG49180.1 - 8.8e-56 188.9 9.9 1.1e-55 188.6 6.9 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EMG49180.1 - 1.2e-14 53.3 0.0 2.2e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMG49180.1 - 5.7e-14 51.4 0.1 1e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMG49180.1 - 5.2e-09 35.4 0.0 1.1e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain GCV_H PF01597.14 EMG49180.1 - 0.01 15.4 0.2 0.039 13.6 0.1 2.0 2 0 0 2 2 2 0 Glycine cleavage H-protein APG6 PF04111.7 EMG49180.1 - 7.1 5.5 13.0 24 3.8 7.7 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 HIG_1_N PF04588.8 EMG49181.1 - 3.1e-05 23.6 1.0 3.1e-05 23.6 0.7 3.1 2 2 1 3 3 3 1 Hypoxia induced protein conserved region FA_desaturase PF00487.19 EMG49181.1 - 0.023 14.1 1.0 0.032 13.6 0.6 1.3 1 1 0 1 1 1 0 Fatty acid desaturase PHO4 PF01384.15 EMG49181.1 - 0.065 11.8 0.6 0.082 11.5 0.4 1.2 1 1 0 1 1 1 0 Phosphate transporter family DUF4396 PF14342.1 EMG49181.1 - 0.07 13.2 1.7 4.2 7.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4396) Na_Ca_ex PF01699.19 EMG49182.1 - 6.1e-26 90.6 39.5 1.5e-16 60.3 7.1 3.8 4 1 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EMG49182.1 - 1e-13 51.4 8.1 1e-13 51.4 5.6 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF307) LDB19 PF13002.2 EMG49182.1 - 0.26 10.7 1.0 0.6 9.5 0.7 1.5 1 0 0 1 1 1 0 Arrestin_N terminal like Pro_isomerase PF00160.16 EMG49183.1 - 2.5e-46 157.7 0.0 4.8e-46 156.7 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EMG49183.1 - 3.7e-12 45.7 2.8 5.6e-07 29.1 0.2 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EMG49183.1 - 2.2e-09 36.5 4.9 5e-05 22.9 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EMG49183.1 - 3.9e-08 32.5 5.3 0.00024 20.5 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMG49183.1 - 9.2e-06 25.5 4.4 0.0009 19.1 1.9 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMG49183.1 - 0.0036 17.9 1.7 0.0082 16.7 1.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMG49183.1 - 0.0078 15.9 0.1 0.0078 15.9 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMG49183.1 - 0.021 15.4 1.5 0.086 13.5 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMG49183.1 - 0.085 13.3 0.5 0.085 13.3 0.3 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc5 PF12862.2 EMG49183.1 - 0.11 12.3 0.3 0.29 11.0 0.1 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 5 MIT PF04212.13 EMG49183.1 - 0.13 12.1 9.4 2.5 8.0 0.0 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 EMG49183.1 - 0.45 10.8 3.6 1.7 9.0 0.7 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 EMG49184.1 - 2.3e-59 200.6 0.1 2.7e-59 200.4 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG49184.1 - 6.9e-21 74.4 0.0 1.1e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMG49184.1 - 4e-06 26.7 0.0 2.1e-05 24.3 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMG49184.1 - 0.00068 19.2 0.2 0.0013 18.3 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase ABC1 PF03109.11 EMG49184.1 - 0.05 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 ABC1 family LTV PF04180.9 EMG49185.1 - 1.6e-76 258.5 43.6 2.1e-76 258.1 30.2 1.1 1 0 0 1 1 1 1 Low temperature viability protein MatE PF01554.13 EMG49186.1 - 1.2e-61 207.0 28.3 8e-33 113.3 7.8 3.0 4 0 0 4 4 4 2 MatE Polysacc_synt_C PF14667.1 EMG49186.1 - 1.4e-05 24.9 9.7 1.4e-05 24.9 6.7 4.8 2 1 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain TMEM247 PF15444.1 EMG49186.1 - 0.13 12.0 0.7 0.21 11.4 0.5 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 DUF3789 PF12664.2 EMG49186.1 - 0.86 8.9 6.0 0.19 11.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3789) PIH1 PF08190.7 EMG49187.1 - 1.9e-28 99.9 4.2 2.7e-28 99.3 2.9 1.2 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 DUF1664 PF07889.7 EMG49187.1 - 0.0022 17.7 0.5 0.0022 17.7 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Poxvirus_B22R_N PF13169.1 EMG49187.1 - 0.79 9.9 4.2 0.28 11.4 0.3 2.2 3 0 0 3 3 3 0 Poxvirus B22R protein N-terminal BPL_N PF09825.4 EMG49188.1 - 3.1e-134 447.3 0.1 4.1e-134 446.9 0.1 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal zf-Apc11 PF12861.2 EMG49188.1 - 4.4e-36 122.6 4.6 9.7e-36 121.5 3.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger UbiA PF01040.13 EMG49188.1 - 2.3e-29 102.4 13.8 3.4e-29 101.8 9.6 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family zf-rbx1 PF12678.2 EMG49188.1 - 2.1e-23 82.1 5.5 4.3e-23 81.2 3.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger BPL_LplA_LipB PF03099.14 EMG49188.1 - 3.9e-14 52.7 0.0 8.3e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family zf-RING_2 PF13639.1 EMG49188.1 - 1e-06 28.4 11.4 2.9e-06 27.0 7.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMG49188.1 - 0.018 14.6 10.2 0.046 13.3 7.0 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMG49188.1 - 0.023 14.7 9.0 0.066 13.2 6.3 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EMG49188.1 - 0.069 13.1 5.6 0.18 11.8 3.8 1.8 1 0 0 1 1 1 0 RING-like domain Glyco_hydro_42M PF08532.5 EMG49188.1 - 0.17 11.0 0.1 4.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Beta-galactosidase trimerisation domain zf-RING_4 PF14570.1 EMG49188.1 - 0.35 10.4 8.2 0.29 10.7 0.4 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EMG49188.1 - 0.83 9.4 6.6 1.7 8.3 4.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.1 EMG49188.1 - 1.3 8.8 10.8 2.7 7.7 7.5 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMG49188.1 - 3.1 7.7 7.7 7.8 6.4 5.4 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Alpha-amylase PF00128.19 EMG49189.1 - 1.2e-104 350.0 1.9 2.1e-104 349.3 0.7 1.9 2 0 0 2 2 2 1 Alpha amylase, catalytic domain AA_kinase PF00696.23 EMG49189.1 - 9.4e-30 103.9 0.4 2e-29 102.8 0.3 1.5 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EMG49189.1 - 2.5e-14 52.7 0.1 7.1e-14 51.2 0.1 1.9 1 0 0 1 1 1 1 PUA domain Vps39_2 PF10367.4 EMG49189.1 - 2.7e-05 24.2 0.0 8e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 DUF4224 PF13986.1 EMG49189.1 - 0.029 13.9 0.0 0.081 12.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) MFS_1 PF07690.11 EMG49190.1 - 6.8e-31 107.2 16.9 6.8e-31 107.2 11.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Y_phosphatase PF00102.22 EMG49191.1 - 4e-60 203.0 0.1 7.2e-60 202.2 0.1 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 EMG49191.1 - 3.6e-06 27.3 0.0 1.2e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain DSPc PF00782.15 EMG49191.1 - 2.6e-05 23.8 0.6 0.0001 21.8 0.4 2.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EMG49191.1 - 0.0011 18.9 0.1 0.003 17.6 0.0 1.8 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EMG49191.1 - 0.0065 16.7 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family BUD22 PF09073.5 EMG49192.1 - 0.96 8.4 17.1 1.4 7.9 11.8 1.3 1 0 0 1 1 1 0 BUD22 UvrD-helicase PF00580.16 EMG49193.1 - 1.6e-30 106.5 4.5 2.6e-15 56.5 0.0 3.1 2 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 EMG49193.1 - 2.7e-23 83.0 1.5 1.2e-21 77.5 0.2 2.5 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EMG49193.1 - 4.1e-12 45.6 0.0 7.6e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EMG49193.1 - 4.4e-10 39.5 0.1 8.8e-10 38.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EMG49193.1 - 2.4e-08 33.7 0.0 9.6e-05 22.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMG49193.1 - 0.0025 17.9 0.4 2.2 8.4 0.0 2.5 1 1 0 2 2 2 2 AAA domain DEAD PF00270.24 EMG49193.1 - 0.01 15.3 0.2 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase HTH_28 PF13518.1 EMG49193.1 - 0.013 15.4 0.1 0.48 10.4 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain UvrD_C_2 PF13538.1 EMG49193.1 - 0.014 15.5 0.0 0.037 14.1 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.9 EMG49193.1 - 0.032 13.8 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Helicase DUF2075 PF09848.4 EMG49193.1 - 0.042 12.8 1.3 0.81 8.5 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EMG49193.1 - 0.049 13.4 3.2 0.072 12.9 0.4 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Vps52 PF04129.7 EMG49194.1 - 1.6e-41 142.4 14.2 3.3e-40 138.0 9.8 2.0 1 1 0 1 1 1 1 Vps52 / Sac2 family Mating_N PF12731.2 EMG49194.1 - 0.02 14.7 0.8 0.051 13.4 0.5 1.7 1 0 0 1 1 1 0 Mating-type protein beta 1 Laminin_II PF06009.7 EMG49194.1 - 3.9 7.2 9.4 0.54 10.0 0.7 2.4 2 1 0 2 2 2 0 Laminin Domain II EIF4E-T PF10477.4 EMG49194.1 - 4.2 6.0 6.2 2.5 6.7 0.1 2.3 2 1 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Rep_fac_C PF08542.6 EMG49195.1 - 1.9e-21 75.8 0.2 5.9e-21 74.2 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.24 EMG49195.1 - 8.8e-12 45.3 0.0 1.6e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EMG49195.1 - 9.8e-12 44.8 0.2 4.2e-10 39.5 0.1 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 EMG49195.1 - 1.7e-08 34.3 0.0 2.7e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMG49195.1 - 7.5e-07 29.3 0.0 2.4e-05 24.4 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.10 EMG49195.1 - 9.8e-07 27.8 0.0 0.00026 19.8 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 EMG49195.1 - 4.2e-06 26.3 0.0 7.4e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMG49195.1 - 1.7e-05 24.9 0.0 0.066 13.3 0.0 2.5 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.7 EMG49195.1 - 2.4e-05 23.5 0.0 6.7e-05 22.0 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_10 PF12846.2 EMG49195.1 - 6.9e-05 22.4 0.0 0.015 14.7 0.0 2.6 1 1 2 3 3 3 1 AAA-like domain Viral_helicase1 PF01443.13 EMG49195.1 - 0.00033 20.2 0.0 0.00052 19.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.16 EMG49195.1 - 0.0022 17.1 0.0 0.03 13.4 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 EMG49195.1 - 0.0031 17.0 0.0 0.0061 16.0 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family DNA_pol3_delta PF06144.8 EMG49195.1 - 0.0072 15.8 0.1 0.014 14.9 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_19 PF13245.1 EMG49195.1 - 0.019 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain ATP13 PF12921.2 EMG49195.1 - 0.023 14.0 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ATPase expression NTPase_1 PF03266.10 EMG49195.1 - 0.025 14.2 0.0 0.24 11.0 0.0 2.3 1 1 0 2 2 2 0 NTPase AAA_25 PF13481.1 EMG49195.1 - 0.031 13.6 0.0 0.48 9.8 0.0 2.3 1 1 1 2 2 2 0 AAA domain ArgK PF03308.11 EMG49195.1 - 0.056 12.2 0.0 1.1 7.9 0.0 2.3 1 1 1 2 2 2 0 ArgK protein DEAD PF00270.24 EMG49195.1 - 0.077 12.4 0.0 1.9 7.9 0.0 2.4 1 1 0 2 2 2 0 DEAD/DEAH box helicase DUF3650 PF12368.3 EMG49195.1 - 0.16 11.5 0.6 0.69 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) RNase_P_pop3 PF08228.6 EMG49196.1 - 2.5e-24 85.9 0.0 3.2e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 KH_1 PF00013.24 EMG49197.1 - 0.00017 21.1 1.0 0.00058 19.4 0.3 2.1 2 0 0 2 2 2 1 KH domain AvrE PF11725.3 EMG49197.1 - 0.1 9.5 1.7 0.15 9.0 1.2 1.2 1 0 0 1 1 1 0 Pathogenicity factor TRAPP PF04051.11 EMG49198.1 - 6.4e-41 139.3 0.0 8e-41 139.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component eIF3_subunit PF08597.5 EMG49199.1 - 2.4e-71 240.1 24.2 2.7e-71 240.0 16.7 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF740 PF05340.7 EMG49199.1 - 2.5 6.3 9.7 3 6.0 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Thioredoxin PF00085.15 EMG49201.1 - 6.4e-31 106.1 0.0 7.1e-31 105.9 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EMG49201.1 - 4.5e-09 36.2 0.3 1.9e-06 27.8 0.1 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EMG49201.1 - 1.2e-08 35.0 0.2 1.4e-07 31.7 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EMG49201.1 - 8.3e-06 25.3 0.0 8.8e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 EMG49201.1 - 0.00079 18.2 0.0 0.00087 18.0 0.0 1.0 1 0 0 1 1 1 1 Phosducin Redoxin PF08534.5 EMG49201.1 - 0.0016 18.0 0.1 0.016 14.7 0.0 1.9 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.16 EMG49201.1 - 0.0023 17.5 0.1 0.004 16.8 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.1 EMG49201.1 - 0.0028 17.4 0.0 0.0039 16.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain TraF PF13728.1 EMG49201.1 - 0.0047 16.4 0.0 0.0077 15.7 0.0 1.3 1 1 0 1 1 1 1 F plasmid transfer operon protein Glutaredoxin PF00462.19 EMG49201.1 - 0.0057 16.6 0.0 0.0086 16.0 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DIM1 PF02966.11 EMG49201.1 - 0.0067 15.9 0.0 0.0074 15.8 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 PAS_8 PF13188.1 EMG49201.1 - 0.0086 15.9 0.0 1.8 8.5 0.0 2.2 2 0 0 2 2 2 1 PAS domain DUF2847 PF11009.3 EMG49201.1 - 0.047 13.2 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) HyaE PF07449.6 EMG49201.1 - 0.051 13.4 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 EMG49201.1 - 0.056 13.4 0.2 0.12 12.4 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like Lipase_GDSL_2 PF13472.1 EMG49202.1 - 4.1e-24 85.6 0.0 4.8e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EMG49202.1 - 1.9e-23 83.5 0.2 2.2e-23 83.2 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AP_endonuc_2 PF01261.19 EMG49202.1 - 0.0043 16.3 0.0 0.0077 15.5 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DsrH PF04077.7 EMG49202.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 DsrH like protein zf-LYAR PF08790.6 EMG49203.1 - 1.1e-14 53.7 6.5 1.1e-14 53.7 4.5 2.1 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger LIM PF00412.17 EMG49203.1 - 0.16 12.0 4.9 0.39 10.8 3.4 1.6 1 1 0 1 1 1 0 LIM domain Ribonuclease_T2 PF00445.13 EMG49203.1 - 0.3 10.6 10.7 0.47 10.0 7.4 1.3 1 1 0 1 1 1 0 Ribonuclease T2 family Serinc PF03348.10 EMG49203.1 - 0.39 9.3 3.4 0.41 9.3 2.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) RabGAP-TBC PF00566.13 EMG49203.1 - 3.8 6.9 6.7 5.2 6.4 4.6 1.2 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Csm1 PF12539.3 EMG49204.1 - 1.1e-23 83.5 1.4 1.2e-23 83.3 0.2 1.7 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 LUC7 PF03194.10 EMG49204.1 - 0.064 12.7 4.3 0.062 12.8 3.0 1.2 1 0 0 1 1 1 0 LUC7 N_terminus DUF3629 PF12302.3 EMG49204.1 - 0.064 12.6 2.8 0.09 12.1 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) Exonuc_VII_L PF02601.10 EMG49204.1 - 0.069 12.3 4.7 0.071 12.2 3.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.11 EMG49204.1 - 0.27 9.7 1.4 0.29 9.6 1.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein SSXT PF05030.7 EMG49204.1 - 0.46 10.0 3.7 0.23 11.0 0.4 2.0 1 1 1 2 2 2 0 SSXT protein (N-terminal region) SlyX PF04102.7 EMG49204.1 - 2.4 8.5 8.6 1.1 9.6 1.7 2.6 1 1 1 2 2 2 0 SlyX Ecm29 PF13001.2 EMG49205.1 - 0.031 12.7 5.2 0.046 12.2 3.2 1.5 1 1 1 2 2 2 0 Proteasome stabiliser DASH_Dad1 PF08649.5 EMG49205.1 - 0.034 13.8 1.9 2.2 8.0 0.1 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad1 DUF3408 PF11888.3 EMG49205.1 - 0.036 13.9 3.7 0.045 13.6 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Peptidase_S64 PF08192.6 EMG49205.1 - 0.065 11.5 9.3 0.066 11.5 6.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF935 PF06074.7 EMG49205.1 - 0.094 11.4 7.7 0.1 11.2 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) DUF4584 PF15223.1 EMG49205.1 - 0.11 11.7 10.3 0.12 11.5 7.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4584) DUF1433 PF07252.6 EMG49205.1 - 0.17 12.1 2.8 0.24 11.6 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1433) DUF3530 PF12048.3 EMG49205.1 - 0.17 10.8 10.6 0.22 10.4 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Glyco_hydro_57 PF03065.10 EMG49205.1 - 0.2 10.5 3.5 0.25 10.2 2.4 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Adaptin_binding PF10199.4 EMG49205.1 - 0.21 11.8 6.9 0.29 11.4 4.8 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 POX PF07526.6 EMG49205.1 - 0.31 11.2 4.0 0.38 10.9 2.8 1.2 1 0 0 1 1 1 0 Associated with HOX Adeno_PIX PF03955.9 EMG49205.1 - 0.35 11.4 7.1 0.46 11.0 4.9 1.3 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) ARD PF03079.9 EMG49205.1 - 0.39 10.6 4.4 0.49 10.3 3.1 1.1 1 0 0 1 1 1 0 ARD/ARD' family Dynein_heavy PF03028.10 EMG49205.1 - 0.39 8.6 5.7 0.4 8.6 3.9 1.0 1 0 0 1 1 1 0 Dynein heavy chain and region D6 of dynein motor eIF3_N PF09440.5 EMG49205.1 - 0.42 10.7 6.9 0.68 10.0 4.8 1.4 1 1 0 1 1 1 0 eIF3 subunit 6 N terminal domain Dict-STAT-coil PF09267.5 EMG49205.1 - 0.43 10.8 7.0 0.21 11.8 3.1 1.7 1 1 1 2 2 2 0 Dictyostelium STAT, coiled coil PAF-AH_p_II PF03403.8 EMG49205.1 - 0.47 8.6 4.2 0.58 8.3 2.9 1.0 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Muted PF14942.1 EMG49205.1 - 0.55 10.1 5.2 0.78 9.6 3.6 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein SSP160 PF06933.6 EMG49205.1 - 0.89 7.4 8.3 0.88 7.4 5.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF1501 PF07394.7 EMG49205.1 - 1.4 7.6 4.6 1.5 7.5 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF1098 PF06497.6 EMG49205.1 - 1.6 8.8 9.2 3 7.9 6.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1098) DUF3275 PF11679.3 EMG49205.1 - 1.6 8.2 5.8 1.9 8.0 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) vMSA PF00695.14 EMG49205.1 - 1.8 7.6 5.4 1.9 7.5 3.7 1.0 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DHHW PF14286.1 EMG49205.1 - 2.1 7.5 9.6 2.5 7.3 6.7 1.1 1 0 0 1 1 1 0 DHHW protein PP_M1 PF03012.9 EMG49205.1 - 2.4 7.4 9.0 2.8 7.2 6.3 1.1 1 0 0 1 1 1 0 Phosphoprotein Mit_KHE1 PF10173.4 EMG49205.1 - 3.2 7.5 6.5 5.6 6.7 4.5 1.5 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Macoilin PF09726.4 EMG49205.1 - 3.4 5.8 11.0 4 5.5 7.7 1.0 1 0 0 1 1 1 0 Transmembrane protein RR_TM4-6 PF06459.7 EMG49205.1 - 3.5 7.4 12.4 3.9 7.3 8.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3450 PF11932.3 EMG49205.1 - 3.8 6.6 10.8 4.7 6.4 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DDHD PF02862.12 EMG49205.1 - 4 7.1 9.1 4.8 6.9 6.3 1.2 1 0 0 1 1 1 0 DDHD domain DUF4544 PF15077.1 EMG49205.1 - 6.8 6.1 7.2 9.4 5.6 5.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4544) FlaG PF03646.10 EMG49205.1 - 8.9 6.5 17.2 51 4.0 11.9 1.9 1 1 0 1 1 1 0 FlaG protein Mucin PF01456.12 EMG49205.1 - 9.9 5.9 20.5 13 5.5 14.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein NAD_binding_5 PF07994.7 EMG49206.1 - 1.1e-113 379.5 0.1 1.3e-113 379.3 0.1 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EMG49206.1 - 1.3e-45 153.8 0.3 2.8e-45 152.7 0.2 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF936 PF06075.7 EMG49208.1 - 4.2 6.1 37.8 5.3 5.8 26.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) AF1Q PF15017.1 EMG49209.1 - 0.0028 17.5 0.8 0.0055 16.5 0.5 1.5 1 0 0 1 1 1 1 Drug resistance and apoptosis regulator DUF1980 PF09323.5 EMG49209.1 - 0.012 15.3 1.9 0.012 15.3 1.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Rabaptin PF03528.10 EMG49209.1 - 0.029 14.2 2.2 0.041 13.7 1.5 1.3 1 0 0 1 1 1 0 Rabaptin DUF3394 PF11874.3 EMG49209.1 - 0.08 12.4 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) Molybdopterin PF00384.17 EMG49210.1 - 4.5e-72 243.1 0.0 4e-69 233.4 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 EMG49210.1 - 8.9e-19 67.0 0.5 2.4e-18 65.7 0.4 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 EMG49210.1 - 2.1e-17 62.0 0.3 6.1e-17 60.5 0.2 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 EMG49210.1 - 4e-16 58.9 0.0 9.7e-16 57.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 EMG49210.1 - 3.7e-08 33.0 0.3 3.7e-08 33.0 0.2 2.2 1 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 EMG49210.1 - 0.0086 15.8 0.0 0.26 11.0 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.22 EMG49210.1 - 0.095 12.3 1.0 3 7.6 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.6 EMG49210.1 - 0.21 11.4 2.2 2.8 7.8 1.5 2.5 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Zn_clus PF00172.13 EMG49211.1 - 3.9e-06 26.6 6.2 8.4e-06 25.6 4.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF382 PF04037.8 EMG49212.1 - 5.1e-49 165.3 0.8 1.4e-48 163.9 0.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 EMG49212.1 - 7.3e-19 66.8 0.3 1.3e-18 66.1 0.2 1.4 1 0 0 1 1 1 1 PSP RFXA_RFXANK_bdg PF15289.1 EMG49212.1 - 4.5 7.4 9.0 1.5 9.0 0.9 3.4 3 2 0 3 3 3 0 Regulatory factor X-associated C-terminal binding domain DUF1120 PF06551.7 EMG49213.1 - 0.044 14.0 0.3 0.05 13.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1120) His_Phos_1 PF00300.17 EMG49215.1 - 2.3e-18 66.7 0.0 3.2e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CENP-X PF09415.5 EMG49216.1 - 7.1e-20 70.5 0.0 6.4e-16 57.9 0.0 2.7 2 1 0 2 2 2 2 CENP-S associating Centromere protein X Asparaginase PF00710.15 EMG49217.1 - 3.1e-76 256.2 0.0 4.1e-76 255.8 0.0 1.1 1 0 0 1 1 1 1 Asparaginase DUF1027 PF06265.6 EMG49217.1 - 0.45 10.4 1.9 12 5.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1027) AMP-binding PF00501.23 EMG49218.1 - 8.2e-78 261.6 0.0 1.3e-77 261.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Proteasome PF00227.21 EMG49219.1 - 1.6e-47 161.2 0.1 2.6e-47 160.5 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EMG49219.1 - 5.7e-13 47.8 0.0 1.3e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal TRAPPC9-Trs120 PF08626.6 EMG49220.1 - 0 1039.0 23.6 0 1038.8 16.4 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TRAPPC-Trs85 PF12739.2 EMG49220.1 - 0.0027 16.4 0.5 0.013 14.1 0.2 2.0 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit COX6B PF02297.12 EMG49221.1 - 5.1e-21 74.4 6.5 6.1e-21 74.2 4.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 EMG49221.1 - 1 9.4 4.1 12 6.0 2.9 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EMG49221.1 - 2.1 8.1 6.2 6.1 6.7 0.2 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Aha1_N PF09229.6 EMG49222.1 - 8.8e-38 129.2 0.0 1.4e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EMG49222.1 - 1.6e-14 54.0 0.0 3.7e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein FtsJ PF01728.14 EMG49223.1 - 8.3e-48 162.7 0.0 1e-47 162.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase ADH_N PF08240.7 EMG49224.1 - 1.5e-26 92.3 3.8 1.5e-26 92.3 2.7 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMG49224.1 - 9.2e-19 67.2 0.2 1.8e-18 66.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EMG49224.1 - 0.0072 15.7 0.2 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF2249 PF10006.4 EMG49224.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) 3HCDH_N PF02737.13 EMG49224.1 - 0.14 11.8 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Utp12 PF04003.7 EMG49225.1 - 3e-20 72.1 0.7 5.3e-20 71.3 0.5 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family RAB3GAP2_N PF14655.1 EMG49225.1 - 0.00044 19.3 0.1 0.00097 18.2 0.0 1.5 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40 PF00400.27 EMG49225.1 - 0.031 14.1 0.6 12 5.9 0.0 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat Chordopox_A15 PF05846.7 EMG49226.1 - 0.046 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A15 protein Pneumovirus_M2 PF06436.6 EMG49226.1 - 0.26 10.5 5.2 0.093 11.9 0.4 2.4 3 0 0 3 3 3 0 Pneumovirus matrix protein 2 (M2) Brevenin PF03032.10 EMG49226.1 - 0.48 10.3 5.2 1.2 8.9 3.6 1.7 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family OKR_DC_1_N PF03709.10 EMG49227.1 - 0.076 13.0 0.0 0.092 12.8 0.0 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain FAP PF07174.6 EMG49228.1 - 0.00053 19.3 18.5 0.00059 19.2 12.8 1.0 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) DUF2076 PF09849.4 EMG49228.1 - 0.65 9.9 3.7 0.86 9.5 2.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Mito_fiss_reg PF05308.6 EMG49228.1 - 8 5.7 7.2 9.4 5.5 5.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Gemin6 PF06372.7 EMG49229.1 - 0.00027 20.3 1.5 7.5 5.8 0.0 4.0 1 1 3 4 4 4 1 Gemin6 protein DUF3446 PF11928.3 EMG49229.1 - 0.028 14.5 12.3 0.082 13.1 8.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) DUF3566 PF12089.3 EMG49229.1 - 0.089 12.8 0.1 1.3e+02 2.6 0.0 3.8 4 0 0 4 4 4 0 Transmembrane domain of unknown function (DUF3566) DUF1517 PF07466.6 EMG49229.1 - 0.31 9.9 5.3 0.47 9.3 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Period_C PF12114.3 EMG49229.1 - 5.2 6.6 9.0 8 6.0 6.2 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region RAP1 PF07218.6 EMG49229.1 - 9.8 4.1 9.6 12 3.8 6.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Lamp PF01299.12 EMG49230.1 - 3.4 6.7 9.3 4.8 6.2 6.4 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Utp14 PF04615.8 EMG49232.1 - 7.4e-203 675.7 74.2 7.4e-203 675.7 51.4 2.1 1 1 1 2 2 2 1 Utp14 protein ALO PF04030.9 EMG49233.1 - 1.3e-105 352.6 0.2 2.2e-105 351.9 0.1 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EMG49233.1 - 8e-21 73.9 0.0 2.5e-20 72.3 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain SIS_2 PF13580.1 EMG49233.1 - 0.025 14.2 0.0 0.06 13.0 0.0 1.6 2 0 0 2 2 2 0 SIS domain MFS_1 PF07690.11 EMG49234.1 - 8.2e-45 153.0 42.3 1.1e-43 149.2 29.3 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EMG49234.1 - 3.6e-14 51.9 23.3 4.8e-14 51.4 16.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMG49234.1 - 1.7e-12 46.6 8.6 1.7e-12 46.6 5.9 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter ATG22 PF11700.3 EMG49234.1 - 8.1e-06 24.5 7.1 8.1e-06 24.5 4.9 2.9 2 1 0 2 2 2 1 Vacuole effluxer Atg22 like AAA PF00004.24 EMG49235.1 - 5.6e-38 130.1 0.0 1.3e-37 128.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EMG49235.1 - 2.1e-07 30.7 0.0 5.3e-06 26.2 0.0 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 EMG49235.1 - 5.6e-07 28.8 0.0 9.9e-07 28.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EMG49235.1 - 4.6e-05 23.5 1.4 0.0011 19.1 0.3 2.7 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EMG49235.1 - 0.00029 20.8 0.3 0.023 14.6 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 EMG49235.1 - 0.0012 18.7 0.0 0.0031 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMG49235.1 - 0.0014 18.3 0.1 0.0048 16.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EMG49235.1 - 0.0014 17.4 0.0 0.0023 16.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 EMG49235.1 - 0.0015 17.9 0.0 0.0032 16.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.8 EMG49235.1 - 0.0031 16.4 0.0 0.0057 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EMG49235.1 - 0.0036 18.1 0.5 0.019 15.7 0.0 2.5 3 1 0 3 3 1 1 AAA domain Mg_chelatase PF01078.16 EMG49235.1 - 0.0045 16.1 0.1 0.0084 15.2 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EMG49235.1 - 0.0069 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EMG49235.1 - 0.0092 15.9 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 EMG49235.1 - 0.011 15.1 0.2 0.065 12.6 0.1 2.0 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 EMG49235.1 - 0.014 15.6 0.1 0.051 13.8 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.1 EMG49235.1 - 0.016 14.9 0.1 0.045 13.5 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 EMG49235.1 - 0.026 14.2 0.0 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase KaiC PF06745.8 EMG49235.1 - 0.032 13.3 0.5 2.1 7.3 0.1 2.2 1 1 1 2 2 2 0 KaiC PhoH PF02562.11 EMG49235.1 - 0.035 13.3 0.0 0.064 12.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.1 EMG49235.1 - 0.036 14.0 0.3 0.065 13.2 0.2 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EMG49235.1 - 0.051 13.2 0.0 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 EMG49235.1 - 0.063 12.7 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EMG49235.1 - 0.069 13.1 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 EMG49235.1 - 0.079 13.1 0.0 0.25 11.5 0.0 1.9 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 EMG49235.1 - 0.085 13.1 0.3 0.28 11.4 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_24 PF13479.1 EMG49235.1 - 0.11 12.1 0.2 0.24 10.9 0.2 1.6 1 1 0 1 1 1 0 AAA domain Guanylate_kin PF00625.16 EMG49235.1 - 0.14 11.5 0.1 0.46 9.8 0.0 1.9 2 0 0 2 2 2 0 Guanylate kinase TMF_DNA_bd PF12329.3 EMG49236.1 - 0.0078 16.0 9.1 0.0078 16.0 6.3 4.2 3 1 1 4 4 4 2 TATA element modulatory factor 1 DNA binding GAS PF13851.1 EMG49236.1 - 0.079 12.1 39.5 0.18 10.9 26.0 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EMG49236.1 - 0.39 10.5 36.9 1 9.2 25.6 1.8 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2353 PF09789.4 EMG49236.1 - 1.3 8.1 34.5 2.4 7.3 5.8 2.3 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Phage_lysis PF03245.8 EMG49236.1 - 3.5 7.6 21.8 0.66 9.9 5.5 3.1 2 1 0 3 3 3 0 Bacteriophage Rz lysis protein ATG16 PF08614.6 EMG49236.1 - 8.4 6.1 37.8 0.17 11.6 10.3 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) zinc_ribbon_6 PF14599.1 EMG49237.1 - 0.096 12.4 0.4 0.1 12.4 0.3 1.0 1 0 0 1 1 1 0 Zinc-ribbon Myb_DNA-bind_6 PF13921.1 EMG49238.1 - 1.2e-11 44.4 0.2 2.9e-11 43.3 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EMG49238.1 - 3.5e-06 26.9 0.3 7.8e-06 25.8 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain TAP42 PF04177.7 EMG49239.1 - 2 7.3 10.1 2.1 7.2 7.0 1.0 1 0 0 1 1 1 0 TAP42-like family AA_permease PF00324.16 EMG49240.1 - 3e-115 385.2 37.7 4.1e-115 384.8 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG49240.1 - 6.3e-28 97.4 41.3 9.4e-28 96.9 28.6 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMG49241.1 - 3e-109 365.4 35.5 3.5e-109 365.3 24.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG49241.1 - 3e-28 98.5 37.6 4e-28 98.1 26.0 1.1 1 0 0 1 1 1 1 Amino acid permease DNA_pol_E_B PF04042.11 EMG49242.1 - 1.2e-34 119.4 1.3 2e-34 118.7 0.9 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Prenyltrans PF00432.16 EMG49243.1 - 1.3e-58 194.2 1.5 1.1e-11 44.0 0.0 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EMG49243.1 - 2.3e-32 111.7 0.0 1.4e-13 51.2 0.0 3.7 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EMG49243.1 - 2.7e-09 37.0 0.0 6.3e-07 29.3 0.0 3.2 1 1 2 3 3 3 1 Prenyltransferase-like RuBisCO_small PF00101.15 EMG49243.1 - 0.042 13.7 0.2 0.3 10.9 0.1 2.0 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase, small chain DUF1183 PF06682.7 EMG49245.1 - 0.32 10.5 3.2 0.35 10.4 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) FAD_binding_6 PF00970.19 EMG49246.1 - 2.5e-08 33.9 0.0 4.3e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EMG49246.1 - 4e-07 30.5 0.0 1.3e-06 28.9 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.17 EMG49246.1 - 0.00072 19.8 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 Globin Bromodomain PF00439.20 EMG49247.1 - 1.5e-18 66.4 0.1 6.5e-18 64.4 0.1 2.2 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 EMG49247.1 - 7.7e-07 28.7 0.0 2e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Bromodomain associated DUF575 PF04746.7 EMG49247.1 - 0.51 10.3 1.9 4.1 7.5 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF575) UQ_con PF00179.21 EMG49248.1 - 5.2e-51 171.7 0.0 5.9e-51 171.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMG49248.1 - 2.5e-05 24.0 0.0 3e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMG49248.1 - 0.00034 20.4 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EMG49248.1 - 0.015 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain Fungal_trans_2 PF11951.3 EMG49249.1 - 1.9e-82 276.9 0.9 4.3e-82 275.7 0.6 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG49249.1 - 4e-07 29.8 10.3 8.1e-07 28.8 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nucleoplasmin PF03066.10 EMG49249.1 - 0.93 8.9 11.0 7 6.1 0.2 3.1 3 0 0 3 3 3 0 Nucleoplasmin Sigma70_ner PF04546.8 EMG49249.1 - 1.2 8.7 13.7 0.49 9.9 3.7 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Nop PF01798.13 EMG49250.1 - 3.3e-60 201.7 1.1 4.6e-60 201.2 0.0 1.8 1 1 1 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 EMG49250.1 - 1e-27 95.6 0.2 2.3e-27 94.5 0.1 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EMG49250.1 - 5.7e-06 26.3 0.0 5.7e-06 26.3 0.0 2.9 2 1 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 EMG49250.1 - 0.00028 20.6 38.9 0.00046 19.9 26.9 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.7 EMG49250.1 - 0.3 11.0 17.9 0.47 10.3 12.4 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.12 EMG49250.1 - 0.34 10.6 10.3 0.68 9.6 7.1 1.6 1 0 0 1 1 1 0 DDHD domain MIP-T3 PF10243.4 EMG49250.1 - 2.5 6.4 41.3 3.8 5.8 28.6 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RR_TM4-6 PF06459.7 EMG49250.1 - 3 7.6 21.5 4.8 6.9 14.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 YqfQ PF14181.1 EMG49250.1 - 5.7 6.9 26.3 16 5.5 18.2 1.8 1 0 0 1 1 1 0 YqfQ-like protein F-actin_cap_A PF01267.12 EMG49251.1 - 0.0035 16.4 0.2 0.0046 16.0 0.2 1.2 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Perilipin PF03036.11 EMG49251.1 - 0.0076 15.1 0.1 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Perilipin family CheZ PF04344.8 EMG49251.1 - 0.11 12.1 0.3 7.8 6.0 0.4 2.3 1 1 1 2 2 2 0 Chemotaxis phosphatase, CheZ LamB_YcsF PF03746.11 EMG49251.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 LamB/YcsF family DUF2841 PF11001.3 EMG49252.1 - 5.7e-31 106.9 2.4 1.1e-30 106.0 1.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) RCC1 PF00415.13 EMG49254.1 - 4.8e-17 61.8 0.1 0.00035 20.7 0.0 4.9 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMG49254.1 - 6e-15 54.3 0.7 3.6e-07 29.6 0.1 4.2 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EMG49254.1 - 1.3e-08 34.7 1.0 0.0012 18.8 0.1 2.7 2 0 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.2 EMG49254.1 - 0.00015 22.0 0.2 0.00093 19.4 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMG49254.1 - 0.00021 21.6 1.6 0.1 13.1 0.2 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EMG49254.1 - 0.1 12.4 1.2 9.5 6.2 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat DNA_binding_1 PF01035.15 EMG49255.1 - 4.3e-11 42.3 0.1 7.3e-05 22.4 0.0 2.7 2 1 0 2 2 2 2 6-O-methylguanine DNA methyltransferase, DNA binding domain ComK PF06338.6 EMG49256.1 - 0.084 12.3 1.7 0.15 11.4 1.2 1.3 1 0 0 1 1 1 0 ComK protein PRKCSH PF07915.8 EMG49257.1 - 4.5e-11 43.4 0.7 7.5e-11 42.6 0.5 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EMG49257.1 - 0.075 12.5 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein zf-Mss51 PF13824.1 EMG49258.1 - 4.2e-20 71.3 0.7 9.1e-20 70.2 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 FAD_binding_6 PF00970.19 EMG49260.1 - 7.9e-09 35.5 0.0 1.5e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 EMG49260.1 - 6.1e-07 29.7 0.0 1.7e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Globin NAD_binding_1 PF00175.16 EMG49260.1 - 1e-06 29.2 0.0 2.6e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Coatomer_b_Cpla PF14806.1 EMG49260.1 - 0.011 15.4 0.0 0.09 12.4 0.0 2.1 2 0 0 2 2 2 0 Coatomer beta subunit appendage platform PA-IIL PF07472.6 EMG49261.1 - 0.039 14.1 0.8 3.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Fucose-binding lectin II (PA-IIL) LIM_bind PF01803.11 EMG49262.1 - 0.07 12.2 0.5 0.079 12.0 0.3 1.0 1 0 0 1 1 1 0 LIM-domain binding protein CDC45 PF02724.9 EMG49262.1 - 8.1 4.3 11.2 8.4 4.2 7.8 1.0 1 0 0 1 1 1 0 CDC45-like protein NUDIX PF00293.23 EMG49263.1 - 8.1e-09 35.2 0.0 1.8e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain Brix PF04427.13 EMG49264.1 - 1.7e-55 187.6 4.1 2.7e-55 186.9 2.8 1.3 1 0 0 1 1 1 1 Brix domain DEAD PF00270.24 EMG49265.1 - 1.2e-47 161.5 0.0 7.9e-47 158.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG49265.1 - 6.6e-27 93.1 0.0 1.4e-26 92.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMG49265.1 - 1.5e-05 24.9 0.2 0.0005 19.9 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit FYVE PF01363.16 EMG49266.1 - 2.9e-20 71.9 5.8 2.9e-20 71.9 4.1 3.1 3 1 1 4 4 4 1 FYVE zinc finger zf-RING_2 PF13639.1 EMG49266.1 - 1.2e-11 44.2 2.1 1.2e-11 44.2 1.4 3.8 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMG49266.1 - 7.9e-05 22.6 3.6 7.9e-05 22.6 2.5 4.4 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMG49266.1 - 0.00034 20.6 0.8 0.00034 20.6 0.6 4.0 3 1 1 4 4 4 2 RING-H2 zinc finger zf-C3HC4 PF00097.20 EMG49266.1 - 0.00054 19.5 1.4 0.00054 19.5 1.0 4.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMG49266.1 - 0.041 13.5 1.6 0.041 13.5 1.1 3.1 3 0 0 3 3 3 0 RING-type zinc-finger RINGv PF12906.2 EMG49266.1 - 0.042 13.9 1.9 0.042 13.9 1.3 3.4 3 1 1 4 4 3 0 RING-variant domain zf-dskA_traR PF01258.12 EMG49266.1 - 0.24 11.1 0.1 0.24 11.1 0.0 2.8 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger FYVE_2 PF02318.11 EMG49266.1 - 0.31 10.9 22.2 0.029 14.2 7.0 3.7 3 2 1 4 4 4 0 FYVE-type zinc finger Macoilin PF09726.4 EMG49266.1 - 0.33 9.1 8.2 0.39 8.9 5.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Zip PF02535.17 EMG49266.1 - 3.1 6.6 8.4 4.3 6.2 5.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Med21 PF11221.3 EMG49267.1 - 2.7e-47 160.3 21.5 1.1e-46 158.4 14.9 1.7 1 1 0 1 1 1 1 Subunit 21 of Mediator complex TCP PF03634.8 EMG49267.1 - 0.3 11.4 5.6 0.53 10.6 3.9 1.4 1 0 0 1 1 1 0 TCP family transcription factor Borrelia_lipo_1 PF05714.6 EMG49267.1 - 0.36 9.8 10.5 0.062 12.3 3.7 2.0 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein Plasmodium_Vir PF05795.6 EMG49267.1 - 1.3 8.1 6.8 0.32 10.1 1.6 1.9 2 0 0 2 2 2 0 Plasmodium vivax Vir protein CDK2AP PF09806.4 EMG49267.1 - 1.7 8.8 10.3 2.7 8.1 4.5 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Ndc1_Nup PF09531.5 EMG49267.1 - 3.3 6.0 7.2 3.6 5.8 5.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spore_III_AB PF09548.5 EMG49267.1 - 5.1 6.8 9.9 0.095 12.4 0.9 2.1 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) PMT PF02366.13 EMG49268.1 - 4.6e-52 176.8 13.5 4.6e-52 176.8 9.4 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EMG49268.1 - 5.2e-26 91.3 0.6 6.9e-26 90.9 0.4 1.2 1 0 0 1 1 1 1 MIR domain Ins145_P3_rec PF08709.6 EMG49268.1 - 0.0015 17.5 0.1 0.0029 16.6 0.1 1.3 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor LRR_4 PF12799.2 EMG49269.1 - 8.9e-13 47.5 58.1 2.2e-07 30.3 3.0 9.2 5 3 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG49269.1 - 1.9e-11 43.5 50.4 5.7e-07 29.1 6.5 7.5 6 2 1 7 7 7 3 Leucine rich repeat LRR_1 PF00560.28 EMG49269.1 - 1.6e-07 30.3 42.3 0.15 12.1 0.1 10.0 9 1 1 10 10 10 5 Leucine Rich Repeat LRR_7 PF13504.1 EMG49269.1 - 4.1 8.0 40.6 0.26 11.6 0.7 10.0 12 1 0 12 12 12 0 Leucine rich repeat TMA7 PF09072.5 EMG49270.1 - 6.7e-27 93.7 17.9 7.3e-27 93.6 12.4 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 PBP1_TM PF14812.1 EMG49270.1 - 0.074 13.3 1.2 0.083 13.2 0.9 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FinO_N PF12602.3 EMG49270.1 - 5.6 7.3 9.1 7.4 6.9 6.3 1.3 1 0 0 1 1 1 0 Fertility inhibition protein N terminal WH1 PF00568.18 EMG49271.1 - 3.9e-31 107.0 0.0 5.5e-31 106.5 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 EMG49271.1 - 1.5e-06 27.6 1.2 3.7e-06 26.3 0.8 1.7 1 0 0 1 1 1 1 WH2 motif GCIP PF13324.1 EMG49272.1 - 1.2e-05 24.7 0.0 1.6e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Nit_Regul_Hom PF10126.4 EMG49272.1 - 0.048 13.4 0.1 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII Esterase PF00756.15 EMG49273.1 - 9.7e-51 172.6 0.0 1.2e-50 172.3 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EMG49273.1 - 1.1e-07 31.7 0.0 1.6e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EMG49273.1 - 0.00018 20.4 0.0 0.00028 19.8 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 EMG49273.1 - 0.005 16.0 0.0 0.0082 15.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EMG49273.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 EMG49273.1 - 0.043 13.4 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.15 EMG49273.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMG49273.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family PLA2_B PF01735.13 EMG49274.1 - 4.6e-205 681.4 7.6 5.7e-205 681.1 5.3 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain MFS_1 PF07690.11 EMG49275.1 - 1e-31 109.9 39.7 8.1e-27 93.8 13.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG49275.1 - 2.2e-24 85.8 16.4 3.8e-24 85.0 11.4 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4131 PF13567.1 EMG49275.1 - 0.5 9.7 0.0 0.5 9.7 0.0 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF4131) PRELI PF04707.9 EMG49276.1 - 1.3e-41 141.7 0.1 1.5e-41 141.5 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family COQ9 PF08511.6 EMG49277.1 - 2.5e-27 94.1 0.1 4.3e-27 93.4 0.0 1.4 1 0 0 1 1 1 1 COQ9 POC1 PF10450.4 EMG49279.1 - 3.2e-07 29.3 2.0 1.1e-06 27.6 1.4 2.0 1 1 0 1 1 1 1 POC1 chaperone NADH_u_ox_C PF12853.2 EMG49281.1 - 4e-38 129.0 0.5 5.8e-38 128.5 0.4 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.4 EMG49281.1 - 1.8e-32 111.4 0.0 2.4e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Polysacc_synt_4 PF04669.8 EMG49282.1 - 3.8e-23 81.8 2.2 2.9e-22 78.9 1.6 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis Striatin PF08232.7 EMG49283.1 - 1.9e-26 93.0 11.9 1.9e-26 93.0 8.2 3.9 5 0 0 5 5 5 1 Striatin family 2OG-FeII_Oxy PF03171.15 EMG49284.1 - 1.3e-06 28.5 0.0 2.6e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 EMG49285.1 - 6.3e-30 101.9 7.6 1e-05 25.1 0.1 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat PRP4 PF08799.6 EMG49285.1 - 0.49 9.7 1.8 2.7 7.3 0.1 2.3 2 0 0 2 2 2 0 pre-mRNA processing factor 4 (PRP4) like HDA2-3 PF11496.3 EMG49286.1 - 5.5e-94 314.3 2.9 5.5e-94 314.3 2.0 1.7 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ETF PF01012.16 EMG49287.1 - 9.9e-33 113.1 0.1 1.8e-32 112.3 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ThiF PF00899.16 EMG49287.1 - 5.1e-09 36.0 0.0 1.2e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 ThiF family AAA_17 PF13207.1 EMG49287.1 - 8.7e-05 23.3 0.3 0.0011 19.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EMG49287.1 - 0.0011 18.8 0.1 0.0079 16.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Torsin PF06309.6 EMG49287.1 - 0.0048 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Torsin RNA_helicase PF00910.17 EMG49287.1 - 0.005 17.0 0.2 0.033 14.3 0.1 2.3 2 0 0 2 2 2 1 RNA helicase KAP_NTPase PF07693.9 EMG49287.1 - 0.0055 15.7 0.2 0.0091 15.0 0.0 1.5 2 0 0 2 2 2 1 KAP family P-loop domain PRK PF00485.13 EMG49287.1 - 0.008 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Shikimate_DH PF01488.15 EMG49287.1 - 0.0093 16.0 0.0 0.18 11.8 0.0 2.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Zeta_toxin PF06414.7 EMG49287.1 - 0.014 14.5 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.14 EMG49287.1 - 0.035 13.5 0.2 0.086 12.2 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EMG49287.1 - 0.054 13.8 0.4 0.25 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EMG49287.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 EMG49287.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 EMG49288.1 - 0.0092 15.5 5.9 0.019 14.5 4.1 1.6 1 0 0 1 1 1 1 IncA protein HEAT PF02985.17 EMG49288.1 - 0.013 15.5 0.0 1.8 8.8 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat V_ATPase_I PF01496.14 EMG49288.1 - 0.22 9.3 5.2 0.38 8.5 3.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.6 EMG49288.1 - 0.92 9.2 19.2 0.35 10.5 5.9 2.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 APG6 PF04111.7 EMG49288.1 - 1.9 7.4 18.6 5.1 6.0 12.9 1.7 1 0 0 1 1 1 0 Autophagy protein Apg6 Macoilin PF09726.4 EMG49288.1 - 1.9 6.6 28.6 0.012 13.9 7.7 2.1 1 1 1 2 2 2 0 Transmembrane protein Fib_alpha PF08702.5 EMG49288.1 - 2.2 8.3 20.2 1.2 9.2 11.0 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Phage_GP20 PF06810.6 EMG49288.1 - 5.7 6.3 28.4 2.8 7.3 6.8 2.9 2 1 1 3 3 3 0 Phage minor structural protein GP20 TMPIT PF07851.8 EMG49288.1 - 6.4 5.7 13.1 29 3.6 9.4 1.9 2 0 0 2 2 2 0 TMPIT-like protein TSC22 PF01166.13 EMG49288.1 - 9.4 6.2 17.4 0.068 13.1 0.5 3.7 1 1 2 3 3 3 0 TSC-22/dip/bun family SCO1-SenC PF02630.9 EMG49289.1 - 4.2e-60 202.3 0.0 5.7e-60 201.8 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EMG49289.1 - 0.00066 19.3 0.0 0.0033 17.1 0.0 2.1 1 1 1 2 2 2 1 AhpC/TSA family DUF4366 PF14283.1 EMG49289.1 - 0.045 13.1 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3295 PF11702.3 EMG49289.1 - 0.17 10.8 0.2 0.19 10.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) SET PF00856.23 EMG49290.1 - 0.00027 21.2 0.0 0.001 19.4 0.0 2.1 1 1 0 1 1 1 1 SET domain Pho88 PF10032.4 EMG49291.1 - 6.8e-87 289.6 0.1 7.6e-87 289.5 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Glucos_trans_II PF14264.1 EMG49291.1 - 0.019 13.9 0.3 0.025 13.5 0.2 1.2 1 0 0 1 1 1 0 Glucosyl transferase GtrII SNase PF00565.12 EMG49292.1 - 3.3e-38 130.2 2.9 5e-10 39.6 0.1 5.9 5 1 1 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EMG49292.1 - 3.2e-13 49.5 0.0 6.7e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Tudor domain Cren7 PF11520.3 EMG49292.1 - 0.13 11.9 0.0 24 4.6 0.0 3.3 3 0 0 3 3 3 0 Chromatin protein Cren7 Amino_oxidase PF01593.19 EMG49293.1 - 1.2e-62 212.5 0.0 4.2e-62 210.7 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase UQ_con PF00179.21 EMG49293.1 - 1.9e-43 147.2 0.0 3.1e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NAD_binding_8 PF13450.1 EMG49293.1 - 2.2e-14 53.2 0.0 4.3e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMG49293.1 - 0.00013 21.7 0.0 0.00076 19.2 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EMG49293.1 - 0.0006 18.8 0.0 0.044 12.6 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMG49293.1 - 0.0026 17.8 0.0 0.031 14.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMG49293.1 - 0.016 13.7 0.1 0.14 10.6 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein DUF1829 PF08862.5 EMG49293.1 - 0.03 14.5 0.6 0.083 13.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF1829 Pyr_redox PF00070.22 EMG49293.1 - 0.032 14.6 0.1 0.32 11.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Transp_cyt_pur PF02133.10 EMG49294.1 - 2.6e-21 75.7 27.7 3.8e-21 75.1 19.2 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2663 PF10864.3 EMG49294.1 - 0.15 12.3 3.3 4.5 7.4 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2663) Bunya_G2 PF03563.8 EMG49294.1 - 0.15 10.8 4.6 0.31 9.8 3.2 1.4 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 TENA_THI-4 PF03070.11 EMG49295.1 - 1.3e-12 47.9 0.6 1.6e-12 47.6 0.4 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family HAUS6_N PF14661.1 EMG49295.1 - 0.0099 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Proteasome PF00227.21 EMG49296.1 - 1.5e-60 203.7 0.0 1.7e-60 203.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMG49296.1 - 7.9e-08 31.4 1.1 2.4e-07 29.9 0.0 2.4 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature ABC_tran PF00005.22 EMG49297.1 - 1.3e-50 171.2 0.0 2.7e-27 95.7 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EMG49297.1 - 7.1e-14 52.4 7.1 0.00021 21.3 0.1 5.2 4 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 EMG49297.1 - 7.4e-13 48.2 0.0 9.7e-05 21.6 0.0 3.5 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EMG49297.1 - 6.4e-09 35.2 0.2 0.0019 17.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Chromo PF00385.19 EMG49297.1 - 2.2e-08 33.6 1.7 5.3e-08 32.4 1.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.1 EMG49297.1 - 5.5e-08 33.3 5.3 0.00044 20.6 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_17 PF13207.1 EMG49297.1 - 2.2e-07 31.7 0.0 0.046 14.5 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EMG49297.1 - 6.5e-07 28.7 0.1 0.078 12.0 0.0 3.9 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 EMG49297.1 - 1.2e-06 27.8 0.0 0.0063 15.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EMG49297.1 - 1.8e-06 27.8 0.0 0.029 14.3 0.0 3.2 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_28 PF13521.1 EMG49297.1 - 9.4e-06 25.6 0.0 0.067 13.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 EMG49297.1 - 1.7e-05 24.3 0.3 0.2 11.0 0.0 3.6 3 0 0 3 3 3 2 AAA-like domain AAA_22 PF13401.1 EMG49297.1 - 2.1e-05 24.7 0.0 0.42 10.7 0.0 3.2 3 0 0 3 3 2 2 AAA domain ArgK PF03308.11 EMG49297.1 - 7e-05 21.7 0.2 0.16 10.7 0.0 2.4 2 0 0 2 2 2 2 ArgK protein DUF87 PF01935.12 EMG49297.1 - 9.4e-05 22.3 4.7 0.0082 15.9 0.0 4.2 4 0 0 4 4 4 1 Domain of unknown function DUF87 AAA_18 PF13238.1 EMG49297.1 - 0.00015 22.0 1.2 0.095 13.0 0.0 3.6 4 0 0 4 4 2 1 AAA domain Miro PF08477.8 EMG49297.1 - 0.00027 21.4 0.0 0.33 11.4 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein RNA_helicase PF00910.17 EMG49297.1 - 0.00033 20.7 0.1 0.46 10.6 0.0 3.0 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 EMG49297.1 - 0.00083 19.2 0.0 0.78 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EMG49297.1 - 0.0013 18.5 0.1 5 7.1 0.0 3.7 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EMG49297.1 - 0.0015 18.2 0.0 0.19 11.4 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EMG49297.1 - 0.0022 17.1 0.2 3.4 6.7 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin NACHT PF05729.7 EMG49297.1 - 0.0028 17.3 0.0 2.4 7.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA PF00004.24 EMG49297.1 - 0.0058 16.8 0.0 4.8 7.3 0.0 3.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EMG49297.1 - 0.0069 15.9 0.8 3.9 7.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EMG49297.1 - 0.0078 16.2 1.0 0.25 11.2 0.0 3.1 4 0 0 4 4 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EMG49297.1 - 0.01 15.3 0.4 0.64 9.4 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_14 PF13173.1 EMG49297.1 - 0.013 15.4 0.0 0.84 9.5 0.0 3.0 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EMG49297.1 - 0.013 14.4 0.5 0.91 8.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Thymidylate_kin PF02223.12 EMG49297.1 - 0.014 14.7 0.3 0.13 11.6 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase AAA_25 PF13481.1 EMG49297.1 - 0.022 14.1 0.0 5.4 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EMG49297.1 - 0.026 14.2 0.1 3.2 7.4 0.0 2.9 3 0 0 3 3 2 0 NTPase cobW PF02492.14 EMG49297.1 - 0.035 13.5 0.9 14 5.0 0.0 3.5 4 0 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 EMG49297.1 - 0.039 13.7 0.9 6.7 6.5 0.0 3.6 3 1 0 3 3 3 0 Dynamin family MutS_V PF00488.16 EMG49297.1 - 0.081 12.3 0.1 9.4 5.5 0.0 2.4 2 0 0 2 2 2 0 MutS domain V AAA_19 PF13245.1 EMG49297.1 - 0.11 12.2 0.5 2.2 8.0 0.0 2.9 3 0 0 3 3 3 0 Part of AAA domain LRR_4 PF12799.2 EMG49298.1 - 2.1e-14 52.7 28.8 5e-08 32.4 1.9 5.5 5 1 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG49298.1 - 3.4e-12 45.9 13.6 3.2e-08 33.2 0.5 4.1 3 1 1 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 EMG49298.1 - 0.0022 17.7 18.5 0.17 11.9 1.1 6.5 5 1 1 6 6 6 1 Leucine Rich Repeat LRR_7 PF13504.1 EMG49298.1 - 0.044 13.9 11.4 9.2 6.9 0.9 6.0 5 0 0 5 5 5 0 Leucine rich repeat Glyco_hydro_3 PF00933.16 EMG49299.1 - 1.3e-89 300.1 0.0 1.7e-89 299.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMG49299.1 - 2e-51 174.6 0.0 3.7e-51 173.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMG49299.1 - 7.3e-22 77.0 0.0 1.4e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Ldl_recept_a PF00057.13 EMG49299.1 - 1.5 8.7 4.7 13 5.7 0.0 2.6 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A MFS_1 PF07690.11 EMG49300.1 - 2.2e-50 171.3 31.7 2.3e-49 167.9 22.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG49300.1 - 1.8e-14 53.1 25.6 2.1e-13 49.6 6.3 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EMG49300.1 - 2.8e-14 52.2 21.6 6.2e-14 51.1 15.0 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 EMG49300.1 - 2.6e-05 22.9 6.5 2.6e-05 22.9 4.5 3.4 3 1 0 4 4 4 1 Vacuole effluxer Atg22 like DUF4131 PF13567.1 EMG49300.1 - 0.2 11.0 11.4 13 5.1 0.1 4.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) Macoilin PF09726.4 EMG49301.1 - 3.5 5.7 21.1 4.1 5.5 14.6 1.1 1 0 0 1 1 1 0 Transmembrane protein FAM176 PF14851.1 EMG49301.1 - 6.6 6.4 6.5 2.5 7.7 2.7 1.7 2 0 0 2 2 2 0 FAM176 family LIP PF03583.9 EMG49302.1 - 3.4e-75 252.9 0.0 4.5e-75 252.5 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.16 EMG49302.1 - 0.028 13.6 0.1 7.1 5.7 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Peptidase_M16 PF00675.15 EMG49303.1 - 5.3e-29 100.9 0.0 2.2e-28 98.8 0.0 2.1 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EMG49303.1 - 9.1e-10 38.5 2.0 2.3e-05 24.1 0.2 2.9 2 0 0 2 2 2 2 Peptidase M16 inactive domain HSD3 PF15244.1 EMG49304.1 - 0.094 11.9 0.7 0.095 11.9 0.5 1.0 1 0 0 1 1 1 0 Hydroxy-steroid dehydrogenase VAD1-2 PF15310.1 EMG49304.1 - 0.57 9.7 3.9 0.56 9.8 2.7 1.0 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling SRP1_TIP1 PF00660.12 EMG49305.1 - 2.7e-15 56.0 0.1 3.3e-15 55.7 0.1 1.1 1 0 0 1 1 1 1 Seripauperin and TIP1 family YebO PF13974.1 EMG49305.1 - 0.021 14.5 0.2 0.031 14.0 0.2 1.3 1 0 0 1 1 1 0 YebO-like protein FAD_binding_6 PF00970.19 EMG49306.1 - 9.7e-23 80.1 0.0 1.5e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EMG49306.1 - 2.7e-18 66.5 0.0 2.6e-17 63.3 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EMG49306.1 - 9.2e-10 38.6 0.2 3.1e-07 30.4 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EMG49306.1 - 0.02 14.8 0.0 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Aldo_ket_red PF00248.16 EMG49307.1 - 8e-41 139.7 0.0 9.1e-41 139.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HMG_CoA_synt_C PF08540.5 EMG49309.1 - 3e-111 371.4 4.8 3.7e-111 371.1 3.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EMG49309.1 - 1.1e-90 301.7 0.5 1.7e-90 301.1 0.4 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal PTR PF12789.2 EMG49310.1 - 0.14 12.0 2.9 0.26 11.1 2.0 1.4 1 0 0 1 1 1 0 Phage tail repeat like Ish1 PF10281.4 EMG49311.1 - 6.4e-41 138.0 27.6 8.2e-12 44.9 0.8 8.0 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein SAP PF02037.22 EMG49311.1 - 4.9e-09 35.4 0.0 3.5 7.2 0.0 7.4 8 1 0 8 8 8 2 SAP domain HeH PF12949.2 EMG49311.1 - 1.8e-07 30.5 1.2 0.0066 15.9 0.0 4.8 6 0 0 6 6 6 2 HeH/LEM domain Endonuc-dimeris PF09124.5 EMG49311.1 - 0.00011 21.8 5.3 0.3 10.7 0.0 4.5 4 0 0 4 4 4 2 T4 recombination endonuclease VII, dimerisation Apolipoprotein PF01442.13 EMG49311.1 - 0.00021 20.8 6.9 0.0086 15.6 0.4 3.3 4 0 0 4 4 4 2 Apolipoprotein A1/A4/E domain Slx4 PF09494.5 EMG49311.1 - 0.044 13.5 3.5 27 4.5 0.0 5.1 5 0 0 5 5 5 0 Slx4 endonuclease DUF725 PF05267.7 EMG49311.1 - 0.055 13.3 1.6 0.43 10.4 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF725) HiaBD2 PF15403.1 EMG49311.1 - 0.093 12.8 1.7 5.9 7.1 0.0 3.5 3 0 0 3 3 3 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) DUF883 PF05957.8 EMG49311.1 - 0.57 10.6 12.2 11 6.5 1.5 4.7 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF883) Prominin PF05478.6 EMG49311.1 - 1.1 6.7 11.4 0.85 7.0 0.4 3.5 2 1 2 4 4 4 0 Prominin Tape_meas_lam_C PF09718.5 EMG49311.1 - 5.2 7.0 12.2 4.3 7.3 0.1 5.2 4 1 1 5 5 5 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Tubulin PF00091.20 EMG49312.1 - 5.2e-67 225.8 0.0 7.5e-67 225.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMG49312.1 - 2.6e-49 166.4 0.1 4.3e-49 165.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain PIR PF00399.14 EMG49314.1 - 1.5e-12 46.3 116.1 0.0036 16.5 2.6 10.5 10 0 0 10 10 10 9 Yeast PIR protein repeat Med15 PF09606.5 EMG49314.1 - 4.5 5.3 44.2 5.5 5.0 30.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pkinase PF00069.20 EMG49315.1 - 5.2e-71 238.8 0.5 2.6e-70 236.5 0.4 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG49315.1 - 5.6e-33 114.1 0.1 6.6e-23 81.1 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EMG49315.1 - 3.8e-07 29.3 0.2 0.036 13.0 0.0 3.0 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 EMG49315.1 - 0.0086 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Fzo_mitofusin PF04799.8 EMG49315.1 - 0.047 13.0 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 fzo-like conserved region APH PF01636.18 EMG49315.1 - 0.071 12.8 0.0 9.1 5.9 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family 2-Hacid_dh_C PF02826.14 EMG49316.1 - 2.6e-50 170.0 0.0 3.8e-50 169.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMG49316.1 - 3.9e-15 55.4 0.0 4.9e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMG49316.1 - 6.5e-06 26.0 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EMG49316.1 - 4.3e-05 23.8 0.1 8.9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 EMG49316.1 - 0.00017 21.0 0.0 0.0003 20.2 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 EMG49316.1 - 0.0047 17.0 0.1 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 EMG49316.1 - 0.022 14.5 0.1 0.96 9.1 0.1 2.3 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AdoHcyase_NAD PF00670.16 EMG49316.1 - 0.051 13.4 0.0 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UPF0081 PF03652.10 EMG49316.1 - 0.13 12.4 0.5 0.26 11.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0081) VPS28 PF03997.7 EMG49317.1 - 2.6e-41 141.3 1.1 5e-40 137.1 0.7 2.0 1 1 0 1 1 1 1 VPS28 protein AKAP95 PF04988.7 EMG49317.1 - 0.088 12.5 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.21 EMG49318.1 - 6.3e-10 38.7 8.7 0.00028 21.0 0.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMG49318.1 - 1.7e-07 31.0 7.8 0.0011 19.1 1.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMG49318.1 - 3.9e-06 26.8 12.1 3.9e-06 26.8 0.0 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.2 EMG49318.1 - 0.00013 22.0 2.6 0.00016 21.7 0.4 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF1712 PF08217.6 EMG49318.1 - 0.0039 15.4 7.8 0.0061 14.8 5.4 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) zf-C2H2_jaz PF12171.3 EMG49318.1 - 0.0082 16.2 2.2 0.01 15.9 0.3 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EMG49318.1 - 0.012 15.3 4.1 0.024 14.3 0.3 2.4 2 0 0 2 2 2 0 BED zinc finger DUF2433 PF10360.4 EMG49320.1 - 1.2e-34 119.5 1.8 6.5e-34 117.0 0.1 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.2 EMG49320.1 - 0.001 18.9 0.0 0.0023 17.7 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NADH_B2 PF14813.1 EMG49321.1 - 0.00053 19.5 0.2 0.00058 19.4 0.1 1.2 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 Bac_luciferase PF00296.15 EMG49322.1 - 1.4e-55 188.6 0.1 2.4e-55 187.8 0.0 1.4 1 0 0 1 1 1 1 Luciferase-like monooxygenase SAP PF02037.22 EMG49323.1 - 5.7e-15 54.4 0.1 1.5e-14 53.0 0.1 1.8 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 EMG49323.1 - 0.00014 21.3 1.5 0.0003 20.2 0.2 2.2 2 1 0 2 2 2 1 HeH/LEM domain DUF966 PF06136.8 EMG49323.1 - 0.87 8.9 9.8 1.1 8.6 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) LUC7 PF03194.10 EMG49323.1 - 6.2 6.2 13.4 25 4.3 9.3 1.9 1 1 0 1 1 1 0 LUC7 N_terminus Ank_2 PF12796.2 EMG49324.1 - 1e-10 41.7 0.0 1.7e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMG49324.1 - 6.4e-08 32.9 0.0 0.00017 22.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EMG49324.1 - 1.5e-06 27.6 0.0 0.00071 19.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EMG49324.1 - 3.6e-06 27.0 0.0 1.4e-05 25.1 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMG49324.1 - 0.0013 18.7 0.1 4 7.9 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Y_phosphatase2 PF03162.8 EMG49325.1 - 2.4e-50 170.1 0.1 2.8e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EMG49325.1 - 1.9e-07 31.5 0.0 2.9e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EMG49325.1 - 0.0039 16.7 0.2 0.014 14.9 0.1 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain GIY-YIG PF01541.19 EMG49325.1 - 0.0067 16.7 0.1 0.015 15.6 0.1 1.6 2 0 0 2 2 2 1 GIY-YIG catalytic domain Y_phosphatase PF00102.22 EMG49325.1 - 0.093 12.0 0.1 0.16 11.2 0.1 1.5 1 1 0 1 1 1 0 Protein-tyrosine phosphatase LAP1C PF05609.7 EMG49326.1 - 0.89 8.1 5.0 0.28 9.8 0.8 1.8 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) LRR_8 PF13855.1 EMG49327.1 - 1.3e-14 53.7 18.6 9.7e-06 25.2 0.0 6.9 6 1 1 7 7 7 4 Leucine rich repeat LRR_4 PF12799.2 EMG49327.1 - 1.1e-07 31.3 30.1 0.00066 19.2 0.0 8.2 4 4 3 8 8 8 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMG49327.1 - 0.00029 20.4 22.0 7.2 7.0 0.1 8.6 8 2 0 8 8 8 4 Leucine Rich Repeat LRR_7 PF13504.1 EMG49327.1 - 0.057 13.6 17.7 25 5.6 0.1 8.9 12 1 0 12 12 12 0 Leucine rich repeat FNIP PF05725.7 EMG49327.1 - 0.18 11.8 30.3 7.2 6.6 0.1 7.3 6 2 1 7 7 7 0 FNIP Repeat LRR_6 PF13516.1 EMG49327.1 - 0.72 10.1 20.4 1.5 9.1 0.3 7.0 9 0 0 9 9 9 0 Leucine Rich repeat Ras PF00071.17 EMG49328.1 - 3.1e-57 192.4 0.0 4.2e-57 192.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMG49328.1 - 3e-19 69.6 0.3 7e-19 68.4 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMG49328.1 - 8.2e-10 38.1 0.0 1.2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMG49328.1 - 7.8e-07 28.7 0.1 4.5e-06 26.2 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMG49328.1 - 4.8e-05 23.2 0.0 0.0001 22.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMG49328.1 - 0.076 12.2 0.1 0.25 10.6 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_25 PF13481.1 EMG49328.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DAD PF02109.11 EMG49329.1 - 5.6e-44 148.8 5.3 6.7e-44 148.5 3.6 1.0 1 0 0 1 1 1 1 DAD family DUF3432 PF11914.3 EMG49329.1 - 0.019 14.9 0.5 0.029 14.4 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) DUF3989 PF13150.1 EMG49329.1 - 0.066 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) CCD PF07860.6 EMG49329.1 - 0.14 11.5 0.1 0.2 11.1 0.1 1.2 1 0 0 1 1 1 0 WisP family C-Terminal Region ING PF12998.2 EMG49331.1 - 1.7e-23 82.8 0.4 5.9e-23 81.1 0.3 2.0 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EMG49331.1 - 1.2e-08 34.5 7.8 2.3e-08 33.5 5.4 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EMG49331.1 - 0.04 13.2 2.0 0.078 12.3 1.4 1.5 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.1 EMG49331.1 - 0.06 13.4 0.8 0.16 12.1 0.6 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain Hyphal_reg_CWP PF11765.3 EMG49332.1 - 3.3e-116 387.6 7.6 3.8e-116 387.4 5.3 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal GIDE PF12483.3 EMG49332.1 - 0.008 15.5 0.0 0.13 11.5 0.0 2.1 2 0 0 2 2 2 1 E3 Ubiquitin ligase LRR_8 PF13855.1 EMG49334.1 - 0.05 13.3 19.3 0.18 11.5 0.3 6.4 7 1 0 7 7 7 0 Leucine rich repeat bZIP_1 PF00170.16 EMG49335.1 - 1.8e-16 59.8 1.5 3.5e-16 58.9 1.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMG49335.1 - 1.4e-10 40.8 6.0 2.7e-10 39.9 4.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMG49335.1 - 0.00088 19.5 3.2 0.0017 18.6 2.2 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF904 PF06005.7 EMG49335.1 - 0.019 15.2 0.9 0.032 14.5 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) HALZ PF02183.13 EMG49335.1 - 0.08 12.6 1.0 0.14 11.8 0.7 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Sec2p PF06428.6 EMG49335.1 - 0.25 11.1 3.8 0.16 11.7 0.9 1.8 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p TUG-UBL1 PF11470.3 EMG49336.1 - 5.6e-18 64.6 1.8 1.2e-17 63.5 1.3 1.6 1 0 0 1 1 1 1 GLUT4 regulating protein TUG Transp_cyt_pur PF02133.10 EMG49337.1 - 2.9e-73 246.9 38.3 3.8e-73 246.5 26.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2207 PF09972.4 EMG49337.1 - 0.17 10.4 6.2 0.4 9.2 0.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) UCH PF00443.24 EMG49338.1 - 1.1e-56 191.9 5.9 1.1e-56 191.9 4.1 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMG49338.1 - 2.2e-29 102.8 5.7 2.2e-29 102.8 3.9 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EMG49338.1 - 3.1e-13 49.6 10.7 3.1e-13 49.6 7.4 2.7 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_C98 PF15499.1 EMG49338.1 - 0.00089 18.6 0.1 0.00089 18.6 0.1 3.6 4 0 0 4 4 4 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Fer4_10 PF13237.1 EMG49338.1 - 0.015 15.0 0.9 0.015 15.0 0.6 3.4 3 1 0 3 3 3 0 4Fe-4S dicluster domain stn_TNFRSF12A PF12191.3 EMG49338.1 - 0.05 13.6 0.1 0.05 13.6 0.1 2.5 3 0 0 3 3 3 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Glyco_hydro_76 PF03663.9 EMG49339.1 - 9.4e-29 100.9 23.0 1.2e-28 100.5 16.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Prenyltrans_2 PF13249.1 EMG49339.1 - 1.2e-06 28.8 2.7 1.2e-06 28.8 1.8 2.0 1 1 1 2 2 2 1 Prenyltransferase-like C5-epim_C PF06662.8 EMG49339.1 - 8.4e-06 25.1 3.8 0.00031 20.0 0.0 3.2 3 1 1 4 4 4 2 D-glucuronyl C5-epimerase C-terminus GlcNAc_2-epim PF07221.6 EMG49339.1 - 0.023 13.7 0.3 2.4 7.1 0.0 2.4 1 1 1 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Rap1-DNA-bind PF09197.5 EMG49340.1 - 3.7e-24 85.2 14.2 1.2e-20 73.9 1.9 3.9 3 1 0 3 3 3 2 Rap1, DNA-binding Myb_DNA-bind_2 PF08914.6 EMG49340.1 - 7.6e-08 32.0 5.1 7.6e-05 22.4 0.1 2.8 2 1 0 2 2 2 2 Rap1 Myb domain Myb_DNA-binding PF00249.26 EMG49340.1 - 0.91 9.6 5.3 0.45 10.6 0.5 2.9 3 1 0 3 3 3 0 Myb-like DNA-binding domain ABC_membrane PF00664.18 EMG49341.1 - 3.2e-59 200.6 44.3 7.9e-38 130.4 10.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMG49341.1 - 7e-46 155.9 0.7 9.2e-30 103.7 0.0 3.5 3 1 0 3 3 2 2 ABC transporter SMC_N PF02463.14 EMG49341.1 - 9.7e-10 38.0 8.2 0.0082 15.3 0.1 4.3 2 2 2 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMG49341.1 - 2.6e-07 30.9 29.6 0.0013 18.7 0.3 6.6 5 2 1 6 6 5 2 AAA domain AAA_17 PF13207.1 EMG49341.1 - 8.1e-07 29.8 1.4 0.067 14.0 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EMG49341.1 - 1e-06 28.1 1.3 0.016 14.7 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EMG49341.1 - 4.6e-06 25.9 1.3 0.019 14.1 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EMG49341.1 - 7.4e-06 25.9 0.4 0.037 13.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 EMG49341.1 - 4.8e-05 23.7 6.2 0.18 12.0 0.4 3.6 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EMG49341.1 - 0.00024 21.1 0.7 0.029 14.3 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain Miro PF08477.8 EMG49341.1 - 0.00033 21.1 1.9 0.27 11.7 0.1 2.9 2 0 0 2 2 2 1 Miro-like protein Zeta_toxin PF06414.7 EMG49341.1 - 0.00051 19.1 3.1 0.26 10.3 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin AAA_18 PF13238.1 EMG49341.1 - 0.00061 20.1 4.7 0.12 12.7 0.0 3.8 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.1 EMG49341.1 - 0.0015 18.1 0.5 0.99 8.9 0.1 2.6 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 EMG49341.1 - 0.0018 17.7 0.1 1.7 7.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMG49341.1 - 0.0031 17.6 1.1 1.3 9.1 0.0 3.4 2 1 0 2 2 2 1 AAA domain Vps51 PF08700.6 EMG49341.1 - 0.005 16.6 0.1 0.038 13.8 0.0 2.6 2 0 0 2 2 1 1 Vps51/Vps67 T2SE PF00437.15 EMG49341.1 - 0.011 14.7 1.5 0.021 13.7 0.1 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP_bind_1 PF03029.12 EMG49341.1 - 0.011 15.2 0.5 8.7 5.7 0.1 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein cobW PF02492.14 EMG49341.1 - 0.027 13.9 2.5 0.069 12.5 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.4 EMG49341.1 - 0.029 12.9 2.0 4.2 5.8 0.1 3.1 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA PF00004.24 EMG49341.1 - 0.031 14.4 1.9 2 8.6 0.2 3.3 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EMG49341.1 - 0.036 13.8 1.2 0.72 9.6 0.1 2.9 3 0 0 3 3 2 0 Part of AAA domain Arch_ATPase PF01637.13 EMG49341.1 - 0.044 13.4 3.6 0.18 11.4 0.0 3.6 3 2 1 4 4 4 0 Archaeal ATPase AAA_14 PF13173.1 EMG49341.1 - 0.059 13.2 1.0 1.5 8.7 0.1 3.3 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 EMG49341.1 - 0.099 12.5 0.4 1 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EMG49341.1 - 0.13 11.0 1.1 8.5 5.0 0.0 2.4 2 0 0 2 2 2 0 ArgK protein NACHT PF05729.7 EMG49341.1 - 0.17 11.5 2.1 0.58 9.7 0.1 2.7 3 0 0 3 3 2 0 NACHT domain PduV-EutP PF10662.4 EMG49341.1 - 0.26 10.7 2.2 3.8 6.9 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EMG49341.1 - 0.29 10.9 6.6 1.2 8.9 0.1 2.8 3 0 0 3 3 2 0 Dynamin family UPF0079 PF02367.12 EMG49341.1 - 0.34 10.5 4.0 0.18 11.4 0.1 2.4 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 EMG49341.1 - 0.37 10.2 1.7 19 4.6 0.2 2.5 3 0 0 3 3 2 0 FtsK/SpoIIIE family Phosducin PF02114.11 EMG49342.1 - 2.6e-13 49.3 1.8 2.6e-13 49.3 1.2 1.7 1 1 1 2 2 2 1 Phosducin DHQS PF01959.11 EMG49342.1 - 0.0054 15.4 0.2 0.0099 14.6 0.1 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase (EC 4.6.1.3) ICAT PF06384.6 EMG49342.1 - 0.035 13.8 0.2 0.067 12.9 0.1 1.5 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT GOLD_2 PF13897.1 EMG49342.1 - 3.4 7.8 5.3 0.6 10.3 0.6 1.8 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking LRR_4 PF12799.2 EMG49343.1 - 2e-07 30.4 63.7 0.034 13.7 1.3 12.2 6 3 5 12 12 12 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG49343.1 - 3.7e-06 26.5 57.1 0.0012 18.5 2.2 9.7 7 1 5 12 12 12 7 Leucine rich repeat LRR_1 PF00560.28 EMG49343.1 - 0.00036 20.1 42.0 8.7 6.8 0.3 13.1 11 3 3 14 14 14 4 Leucine Rich Repeat LRR_7 PF13504.1 EMG49343.1 - 0.02 14.9 34.5 7.8 7.1 0.0 12.9 14 1 1 15 15 15 0 Leucine rich repeat LRR_6 PF13516.1 EMG49343.1 - 1.7 8.9 45.5 0.38 10.9 0.1 11.9 12 1 0 12 12 12 0 Leucine Rich repeat Glyco_hydro_17 PF00332.13 EMG49344.1 - 3e-07 29.7 0.6 6.9e-07 28.5 0.4 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 PPR_2 PF13041.1 EMG49345.1 - 5.3e-15 55.1 0.1 2.7e-11 43.2 0.0 3.1 3 0 0 3 3 3 2 PPR repeat family MA3 PF02847.12 EMG49346.1 - 2.2e-17 62.7 1.9 3.2e-17 62.2 0.4 1.9 2 0 0 2 2 2 1 MA3 domain DUF1777 PF08648.7 EMG49346.1 - 2.8 7.6 20.7 5.7 6.6 14.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Cytochrom_C PF00034.16 EMG49347.1 - 3.3e-10 40.6 0.0 4.5e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EMG49347.1 - 1e-06 28.7 2.4 1.1e-05 25.5 1.7 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EMG49347.1 - 0.06 12.7 1.3 0.21 11.0 0.1 2.1 2 1 1 3 3 3 0 Cytochrome c-550 domain PI31_Prot_N PF11566.3 EMG49348.1 - 2.1e-30 105.3 0.2 2.9e-30 104.9 0.1 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EMG49348.1 - 2.7e-15 56.7 16.0 5.9e-15 55.6 11.1 1.6 1 0 0 1 1 1 1 PI31 proteasome regulator CTP_transf_2 PF01467.21 EMG49349.1 - 3.2e-07 30.5 0.0 9e-07 29.0 0.0 1.8 1 1 0 1 1 1 1 Cytidylyltransferase USP7_ICP0_bdg PF12436.3 EMG49350.1 - 3.5e-45 154.1 3.8 1.6e-44 152.0 1.1 3.0 3 1 0 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.24 EMG49350.1 - 1.8e-40 138.7 2.9 4.7e-40 137.4 2.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 EMG49350.1 - 3.3e-24 85.5 1.6 3.3e-24 85.5 1.1 5.2 5 1 1 6 6 6 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.1 EMG49350.1 - 1.4e-20 73.9 0.0 5.6e-20 71.9 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EMG49350.1 - 2.3e-10 40.7 3.5 1e-08 35.4 0.2 3.5 3 0 0 3 3 3 1 MATH domain Rhodanese PF00581.15 EMG49351.1 - 3e-17 62.9 0.0 3.5e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain Glucosamine_iso PF01182.15 EMG49352.1 - 9.2e-49 165.8 0.0 1.4e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase ABC_membrane PF00664.18 EMG49353.1 - 5.6e-58 196.5 40.2 1.8e-30 106.2 15.4 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMG49353.1 - 1.2e-48 164.9 0.7 7.2e-29 100.8 0.0 3.3 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMG49353.1 - 9.8e-09 34.7 6.6 0.018 14.2 0.1 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EMG49353.1 - 3.7e-08 32.7 0.8 0.0007 19.0 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EMG49353.1 - 1.5e-07 31.6 15.9 2.7e-05 24.3 0.1 5.8 3 2 2 5 5 5 2 AAA domain AAA_17 PF13207.1 EMG49353.1 - 2.6e-05 25.0 2.3 0.39 11.5 0.0 3.7 2 1 1 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 EMG49353.1 - 0.00012 22.0 1.1 0.26 11.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EMG49353.1 - 0.00018 20.7 0.7 0.19 10.9 0.2 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EMG49353.1 - 0.00047 20.6 0.4 0.87 10.1 0.0 3.3 2 0 0 2 2 2 1 Miro-like protein AAA_23 PF13476.1 EMG49353.1 - 0.00064 20.1 21.7 0.003 17.9 3.1 3.9 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.1 EMG49353.1 - 0.0013 18.7 0.8 0.11 12.5 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 EMG49353.1 - 0.0018 17.3 0.0 0.97 8.4 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 EMG49353.1 - 0.0072 15.7 0.0 0.46 9.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 EMG49353.1 - 0.0081 15.7 0.7 9.1 5.7 0.1 3.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.1 EMG49353.1 - 0.0091 15.5 0.9 2.3 7.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 EMG49353.1 - 0.017 13.9 0.1 1.8 7.4 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 EMG49353.1 - 0.026 13.9 0.7 2 7.7 0.0 2.8 2 0 0 2 2 2 0 AAA-like domain ArgK PF03308.11 EMG49353.1 - 0.037 12.7 0.1 6.5 5.4 0.0 2.5 2 0 0 2 2 2 0 ArgK protein FtsK_SpoIIIE PF01580.13 EMG49353.1 - 0.18 11.2 1.2 5.9 6.3 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_18 PF13238.1 EMG49353.1 - 0.27 11.5 10.3 1.6 9.0 0.0 4.1 5 0 0 5 5 3 0 AAA domain cobW PF02492.14 EMG49353.1 - 0.37 10.2 3.8 1.6 8.1 0.1 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EMG49353.1 - 0.75 9.9 6.4 27 4.9 0.2 3.6 2 1 0 2 2 2 0 AAA domain NDUF_B4 PF07225.7 EMG49357.1 - 0.045 13.5 0.2 0.062 13.1 0.1 1.3 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Mis12 PF05859.7 EMG49358.1 - 2.1e-36 124.9 0.5 4e-36 123.9 0.4 1.5 1 0 0 1 1 1 1 Mis12 protein Lzipper-MIP1 PF14389.1 EMG49358.1 - 0.15 12.1 2.9 0.45 10.6 2.0 1.8 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DIOX_N PF14226.1 EMG49359.1 - 2.2e-09 37.8 0.0 4e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMG49359.1 - 7.1e-09 35.8 0.0 1.3e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Dus PF01207.12 EMG49360.1 - 7.4e-47 159.6 0.0 1.5e-46 158.6 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) FMN_dh PF01070.13 EMG49360.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Tim17 PF02466.14 EMG49361.1 - 5.5e-31 107.2 0.2 9.1e-31 106.5 0.1 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ost4 PF10215.4 EMG49362.1 - 1.1e-15 56.7 1.5 1.4e-15 56.4 1.0 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase DUF92 PF01940.11 EMG49362.1 - 0.028 13.5 0.0 0.028 13.5 0.0 1.0 1 0 0 1 1 1 0 Integral membrane protein DUF92 Neugrin PF06413.6 EMG49363.1 - 0.00017 21.5 0.9 0.00042 20.2 0.1 1.8 2 0 0 2 2 2 1 Neugrin DUF4065 PF13274.1 EMG49363.1 - 0.12 13.0 0.2 0.19 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) G3P_antiterm PF04309.7 EMG49364.1 - 0.074 12.0 1.6 0.15 11.1 0.4 2.0 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Peptidase_M20 PF01546.23 EMG49365.1 - 3.5e-27 95.1 0.0 4.3e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMG49365.1 - 1.5e-08 34.3 0.2 3.5e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EMG49365.1 - 0.002 17.8 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 RRM_1 PF00076.17 EMG49366.1 - 7.4e-18 63.9 0.0 1e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG49366.1 - 1.3e-14 53.8 0.0 1.9e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG49366.1 - 8.2e-09 35.1 0.0 1.4e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PMI_typeI PF01238.16 EMG49367.1 - 9.8e-156 518.4 0.0 1.2e-155 518.1 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 EMG49367.1 - 0.00046 19.8 0.0 0.19 11.4 0.0 2.7 3 0 0 3 3 3 2 AraC-like ligand binding domain Thioredoxin PF00085.15 EMG49368.1 - 3.2e-16 58.8 2.2 9.8e-15 54.1 0.0 3.5 4 0 0 4 4 4 1 Thioredoxin Thioredoxin_6 PF13848.1 EMG49368.1 - 2e-07 30.9 6.4 9.8e-06 25.4 0.2 4.2 3 1 0 4 4 4 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EMG49368.1 - 9.7e-05 22.4 4.9 0.00016 21.7 0.0 3.6 3 1 0 3 3 3 1 Thioredoxin-like Thioredoxin_4 PF13462.1 EMG49368.1 - 0.024 14.6 3.0 0.11 12.5 0.2 2.6 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_2 PF13098.1 EMG49368.1 - 0.038 14.1 0.4 0.78 9.9 0.1 2.9 2 0 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EMG49368.1 - 0.067 13.2 0.1 0.23 11.5 0.1 1.9 1 0 0 1 1 1 0 Thioredoxin-like Mito_carr PF00153.22 EMG49369.1 - 3.2e-79 260.7 5.7 3.6e-28 97.1 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NAD_binding_6 PF08030.7 EMG49370.1 - 8.1e-26 90.7 0.0 1.2e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMG49370.1 - 1.6e-24 85.8 0.0 4.5e-24 84.3 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 EMG49370.1 - 9e-18 64.5 12.1 9e-18 64.5 8.4 2.0 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EMG49370.1 - 0.01 16.4 0.0 8.4 7.0 0.0 2.6 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain LRR_4 PF12799.2 EMG49371.1 - 4.7e-05 22.9 29.4 0.013 15.1 0.0 8.5 5 3 2 7 7 7 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG49371.1 - 0.00029 20.5 24.9 0.46 10.2 0.1 7.7 5 3 4 9 9 9 6 Leucine rich repeat FNIP PF05725.7 EMG49371.1 - 0.041 13.8 23.4 5.3 7.0 0.3 7.9 9 0 0 9 9 9 0 FNIP Repeat LRR_2 PF07723.8 EMG49371.1 - 1.6 9.3 6.4 51 4.5 0.1 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat Bac_luciferase PF00296.15 EMG49372.1 - 3.6e-58 197.1 0.0 5.2e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase PQ-loop PF04193.9 EMG49373.1 - 1.9e-34 117.0 7.2 1.8e-19 68.9 0.5 3.6 5 0 0 5 5 5 2 PQ loop repeat TRAM_LAG1_CLN8 PF03798.11 EMG49373.1 - 0.0056 16.2 3.6 0.52 9.8 0.4 2.4 2 0 0 2 2 2 2 TLC domain Zip PF02535.17 EMG49373.1 - 0.0072 15.3 1.0 0.01 14.9 0.1 1.7 2 0 0 2 2 2 1 ZIP Zinc transporter YrhC PF14143.1 EMG49373.1 - 0.028 14.3 1.1 0.073 13.0 0.1 2.3 2 0 0 2 2 2 0 YrhC-like protein RseC_MucC PF04246.7 EMG49373.1 - 1.1 8.8 3.7 2 8.0 0.5 2.7 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF4306 PF14154.1 EMG49373.1 - 2.1 8.4 8.8 0.067 13.1 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4306) SWIRM PF04433.12 EMG49374.1 - 2.6e-12 46.6 0.0 7e-12 45.3 0.0 1.8 2 0 0 2 2 2 1 SWIRM domain ParA PF10609.4 EMG49375.1 - 1.2e-20 73.1 0.2 2.5e-20 72.1 0.1 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EMG49375.1 - 6.8e-15 54.9 0.0 8.6e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EMG49375.1 - 1.6e-08 33.9 0.1 8e-07 28.3 0.0 2.1 1 1 1 2 2 2 1 ATPase MipZ AAA_31 PF13614.1 EMG49375.1 - 4.4e-05 23.4 0.0 0.00013 21.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 EMG49375.1 - 4.7e-05 22.5 0.1 8e-05 21.8 0.1 1.4 2 0 0 2 2 2 1 Anion-transporting ATPase ArgK PF03308.11 EMG49375.1 - 0.00073 18.3 0.1 0.0011 17.8 0.1 1.2 1 0 0 1 1 1 1 ArgK protein APS_kinase PF01583.15 EMG49375.1 - 0.0036 16.9 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase YhjQ PF06564.7 EMG49375.1 - 0.02 14.2 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 YhjQ protein DUF258 PF03193.11 EMG49375.1 - 0.025 13.7 0.1 0.039 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EMG49375.1 - 0.06 12.7 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EMG49375.1 - 0.087 12.2 0.1 1.5 8.2 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MobB PF03205.9 EMG49375.1 - 0.1 12.2 0.3 0.2 11.3 0.2 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EMG49375.1 - 0.13 12.0 0.7 2.5 7.8 0.0 2.4 2 1 0 2 2 2 0 Part of AAA domain Nop16 PF09420.5 EMG49376.1 - 2.5e-58 196.7 13.2 3e-58 196.5 9.1 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Nsp1_C PF05064.8 EMG49377.1 - 0.00055 19.5 0.4 0.00061 19.4 0.3 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region FimP PF09766.4 EMG49377.1 - 0.011 14.8 1.4 0.011 14.7 1.0 1.0 1 0 0 1 1 1 0 Fms-interacting protein DUF2450 PF10475.4 EMG49377.1 - 0.012 14.5 0.1 0.013 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) PAP_RNA-bind PF04926.10 EMG49377.1 - 0.016 14.7 0.1 0.017 14.6 0.1 1.0 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain MscS_porin PF12795.2 EMG49377.1 - 0.02 14.2 4.0 0.021 14.1 2.8 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain LXG PF04740.7 EMG49377.1 - 0.026 14.3 2.5 0.028 14.2 1.8 1.0 1 0 0 1 1 1 0 LXG domain of WXG superfamily Laminin_II PF06009.7 EMG49377.1 - 0.035 13.8 0.5 0.039 13.7 0.3 1.2 1 0 0 1 1 1 0 Laminin Domain II DUF3450 PF11932.3 EMG49377.1 - 0.057 12.6 1.1 0.06 12.6 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) EAP30 PF04157.11 EMG49377.1 - 0.083 12.0 1.4 0.082 12.0 1.0 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family IncA PF04156.9 EMG49377.1 - 0.16 11.5 3.2 0.16 11.5 2.2 1.1 1 0 0 1 1 1 0 IncA protein SGT1 PF07093.6 EMG49377.1 - 0.21 9.8 4.5 0.22 9.8 3.1 1.0 1 0 0 1 1 1 0 SGT1 protein Spc24 PF08286.6 EMG49377.1 - 0.23 11.1 2.8 0.25 11.0 1.9 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 GrpE PF01025.14 EMG49377.1 - 0.32 10.5 4.0 0.32 10.5 2.8 1.0 1 0 0 1 1 1 0 GrpE HMGL-like PF00682.14 EMG49378.1 - 1.1e-69 234.6 0.0 3.8e-69 232.9 0.0 1.8 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.5 EMG49378.1 - 1.2e-27 96.2 0.0 2.3e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain SNARE PF05739.14 EMG49379.1 - 5.6e-13 48.3 3.4 5.6e-13 48.3 2.3 3.0 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EMG49379.1 - 3.8e-05 23.7 9.3 3.8e-05 23.7 6.4 3.2 1 1 2 3 3 3 2 Syntaxin Synaptobrevin PF00957.16 EMG49379.1 - 0.083 12.5 0.3 0.083 12.5 0.2 3.2 3 1 0 3 3 3 0 Synaptobrevin DUF3753 PF12575.3 EMG49379.1 - 0.11 12.2 7.6 2.7 7.8 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) DUF1664 PF07889.7 EMG49379.1 - 5 6.9 11.4 1.5 8.5 0.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) IPK PF03770.11 EMG49380.1 - 2.5e-55 187.1 0.0 3.3e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase GTP_EFTU PF00009.22 EMG49381.1 - 2.1e-46 157.7 0.0 2.8e-45 154.0 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EMG49381.1 - 1.8e-26 92.1 0.2 4.4e-26 90.9 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EMG49381.1 - 2.4e-07 30.7 0.2 6.3e-07 29.4 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMG49381.1 - 0.00012 22.0 0.0 0.00038 20.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase VHS PF00790.14 EMG49382.1 - 3.3e-16 59.2 0.0 6.7e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EMG49382.1 - 0.0012 18.8 0.0 0.0033 17.3 0.0 1.7 1 0 0 1 1 1 1 GAT domain Mito_fiss_reg PF05308.6 EMG49382.1 - 0.67 9.2 12.8 2.9 7.1 1.0 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator CutA1 PF03091.10 EMG49383.1 - 0.94 9.1 5.0 12 5.6 0.1 2.7 1 1 1 2 2 2 0 CutA1 divalent ion tolerance protein SNARE PF05739.14 EMG49384.1 - 0.0004 20.0 2.7 0.00054 19.6 1.8 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 EMG49384.1 - 0.0049 16.3 0.0 0.0059 16.0 0.0 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 AIP3 PF03915.8 EMG49384.1 - 0.01 14.7 0.4 0.011 14.6 0.3 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 Syja_N PF02383.13 EMG49385.1 - 1e-38 132.9 0.3 1.4e-38 132.4 0.2 1.2 1 0 0 1 1 1 1 SacI homology domain Metallophos PF00149.23 EMG49385.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Hyphal_reg_CWP PF11765.3 EMG49386.1 - 1.1e-154 514.1 17.7 1.2e-154 514.0 12.3 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal SRI PF08236.6 EMG49388.1 - 4.3e-22 77.8 6.5 4.3e-22 77.8 4.5 2.9 3 1 0 3 3 3 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.23 EMG49388.1 - 1.1e-19 71.3 0.4 1.1e-19 71.3 0.3 3.5 2 2 0 2 2 2 1 SET domain WW PF00397.21 EMG49388.1 - 1.2e-10 41.0 4.7 2.6e-10 39.9 3.3 1.6 1 0 0 1 1 1 1 WW domain HTH_15 PF12324.3 EMG49388.1 - 0.11 12.2 0.2 0.28 10.8 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase Med26 PF08711.6 EMG49388.1 - 0.22 11.0 2.8 0.66 9.5 1.1 2.5 2 0 0 2 2 2 0 TFIIS helical bundle-like domain Condensin2nSMC PF12422.3 EMG49388.1 - 1 9.0 5.0 0.27 10.9 0.7 2.0 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit NAD_Gly3P_dh_N PF01210.18 EMG49389.1 - 1e-50 171.4 0.0 1.6e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EMG49389.1 - 1.2e-45 154.9 0.4 1.7e-45 154.3 0.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 EMG49389.1 - 0.002 18.5 0.0 2.6 8.5 0.0 2.5 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 EMG49389.1 - 0.02 15.2 0.0 0.11 12.7 0.0 2.1 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain zf-C2H2_4 PF13894.1 EMG49390.1 - 2.6e-10 39.8 2.1 0.00017 21.6 0.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EMG49390.1 - 1.5e-09 37.6 8.1 5.1e-05 23.3 1.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EMG49390.1 - 0.028 14.5 4.3 1 9.6 0.0 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EMG49390.1 - 0.45 10.8 11.1 1.8 8.9 0.6 3.3 3 1 0 3 3 3 0 Zinc-finger double domain TruD PF01142.13 EMG49392.1 - 4.2e-59 200.0 3.8 6.6e-59 199.4 0.1 2.8 3 1 0 3 3 3 1 tRNA pseudouridine synthase D (TruD) Pkinase PF00069.20 EMG49393.1 - 5.2e-71 238.8 0.0 7.1e-71 238.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG49393.1 - 1.9e-38 132.0 0.0 2.6e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG49393.1 - 1.7e-08 33.8 0.0 3.2e-06 26.3 0.0 2.2 1 1 1 2 2 2 2 Kinase-like YrbL-PhoP_reg PF10707.4 EMG49393.1 - 0.0053 16.1 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL DUF4120 PF13496.1 EMG49393.1 - 0.033 14.2 0.1 0.14 12.2 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4120) APH PF01636.18 EMG49393.1 - 0.059 13.0 0.6 0.56 9.8 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family AMP-binding PF00501.23 EMG49394.1 - 1.3e-88 297.1 0.0 1.7e-88 296.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMG49394.1 - 5.7e-21 75.2 0.3 3.7e-19 69.4 0.2 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain HEM4 PF02602.10 EMG49395.1 - 1e-34 119.8 0.0 1.3e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD DUF3788 PF12663.2 EMG49395.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) TIG PF01833.19 EMG49396.1 - 8.3e-12 44.9 0.1 8.3e-12 44.9 0.1 2.6 3 0 0 3 3 3 1 IPT/TIG domain RRM_1 PF00076.17 EMG49397.1 - 4.1e-08 32.7 0.0 6e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG49397.1 - 7.1e-05 22.7 0.0 0.0001 22.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG49397.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.18 EMG49399.1 - 2.4e-96 322.3 1.4 2.4e-96 322.3 1.0 2.0 3 0 0 3 3 3 1 Kinesin motor domain Phage_lysis PF03245.8 EMG49399.1 - 0.012 15.5 2.3 0.22 11.5 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein DUF641 PF04859.7 EMG49399.1 - 0.1 12.3 10.6 0.1 12.3 0.4 3.3 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) Med9 PF07544.8 EMG49399.1 - 0.19 11.4 8.8 0.054 13.2 0.7 2.9 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Pox_A_type_inc PF04508.7 EMG49399.1 - 0.79 9.6 4.1 4.6 7.2 0.0 3.9 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat End3 PF12761.2 EMG49399.1 - 4.1 7.0 10.8 0.26 10.9 1.3 2.9 3 0 0 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 Rho_Binding PF08912.6 EMG49399.1 - 8.4 6.7 9.7 3.7 7.9 0.3 3.3 3 0 0 3 3 3 0 Rho Binding COMP PF11598.3 EMG49399.1 - 8.8 6.4 7.8 3.9 7.6 1.3 2.7 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Metallophos PF00149.23 EMG49400.1 - 1.8e-09 37.2 10.4 3.6e-09 36.3 7.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 EMG49401.1 - 3.7e-09 36.0 6.6 2.9e-07 30.0 0.1 5.3 5 1 2 8 8 8 1 TPR repeat TPR_12 PF13424.1 EMG49401.1 - 4.2e-05 23.3 0.1 8.1 6.4 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMG49401.1 - 7.2e-05 22.2 1.8 7.1 6.6 0.0 5.6 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMG49401.1 - 7.2e-05 22.2 0.6 0.11 12.0 0.1 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMG49401.1 - 0.00022 21.5 0.4 5.5 7.9 0.0 5.0 2 2 2 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMG49401.1 - 0.00093 19.2 4.0 0.13 12.5 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EMG49401.1 - 0.012 15.6 2.3 0.21 11.7 0.4 3.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EMG49401.1 - 0.019 15.2 0.2 2 8.8 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EMG49401.1 - 0.075 13.7 0.2 40 5.0 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMG49401.1 - 2.4 8.2 12.9 1.4 8.9 0.0 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Pkinase PF00069.20 EMG49402.1 - 4.8e-39 134.0 0.0 9.5e-39 133.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG49402.1 - 2.9e-28 98.6 0.0 4.3e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMG49402.1 - 1.2e-05 24.4 0.1 4.5e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMG49402.1 - 0.00077 18.5 0.0 0.0018 17.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like ORC2 PF04084.9 EMG49403.1 - 1.5e-102 342.8 0.4 2.2e-102 342.2 0.3 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Daxx PF03344.10 EMG49403.1 - 0.0072 14.8 19.1 0.01 14.3 13.2 1.1 1 0 0 1 1 1 1 Daxx Family GyrI-like PF06445.10 EMG49403.1 - 0.048 13.6 0.1 1.6 8.7 0.1 2.4 2 0 0 2 2 2 0 GyrI-like small molecule binding domain Lactamase_B_2 PF12706.2 EMG49404.1 - 3e-08 33.4 0.0 5.8e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.9 EMG49404.1 - 2.8e-05 24.1 0.1 8.4e-05 22.5 0.1 1.8 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.22 EMG49404.1 - 0.00077 19.1 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 EMG49404.1 - 0.0052 16.5 0.0 0.025 14.3 0.0 2.2 2 0 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase RRM_1 PF00076.17 EMG49405.1 - 2.9e-05 23.5 0.1 6.3e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG49405.1 - 6.9e-05 22.6 0.0 0.0002 21.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2854 PF11016.3 EMG49405.1 - 0.013 15.0 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) RRM_3 PF08777.6 EMG49405.1 - 0.016 15.0 0.9 0.12 12.2 0.0 2.4 3 0 0 3 3 3 0 RNA binding motif DUF3527 PF12043.3 EMG49405.1 - 0.025 14.0 0.4 0.7 9.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) RRM_6 PF14259.1 EMG49405.1 - 0.042 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Laminin_II PF06009.7 EMG49405.1 - 1.6 8.4 6.0 0.18 11.5 0.4 2.1 3 0 0 3 3 3 0 Laminin Domain II DUF2428 PF10350.4 EMG49406.1 - 1.2e-36 126.0 0.2 7.5e-36 123.4 0.1 2.1 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 EMG49406.1 - 1.4e-05 24.7 1.6 4.6 7.5 0.0 5.4 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.1 EMG49406.1 - 0.041 14.1 0.0 2.5 8.4 0.0 3.6 3 1 0 3 3 3 0 HEAT repeats SNF2_N PF00176.18 EMG49407.1 - 1.3e-61 208.0 0.3 2e-61 207.4 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMG49407.1 - 2.8e-13 49.5 0.0 8.4e-13 48.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMG49407.1 - 3.1e-12 46.3 0.1 1.2e-11 44.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EMG49407.1 - 3.9e-10 39.8 0.0 1.1e-09 38.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EMG49407.1 - 1.7e-05 23.8 3.0 3e-05 23.0 2.1 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF2075 PF09848.4 EMG49407.1 - 0.0064 15.5 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Ank_5 PF13857.1 EMG49408.1 - 2.2e-07 30.8 0.3 4.8e-07 29.8 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMG49408.1 - 0.0011 19.4 0.6 0.075 13.5 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMG49408.1 - 0.0045 17.2 0.1 0.0094 16.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EMG49408.1 - 0.048 13.9 0.6 0.6 10.5 0.1 2.6 2 0 0 2 2 2 0 Ankyrin repeat Cupin_8 PF13621.1 EMG49408.1 - 0.056 12.9 0.9 0.17 11.3 0.0 2.2 2 1 0 2 2 2 0 Cupin-like domain Ank PF00023.25 EMG49408.1 - 0.065 13.0 0.6 0.17 11.7 0.4 1.7 1 0 0 1 1 1 0 Ankyrin repeat Usp PF00582.21 EMG49408.1 - 0.19 11.9 3.7 0.17 12.0 0.2 2.6 3 0 0 3 3 3 0 Universal stress protein family URO-D PF01208.12 EMG49409.1 - 2.6e-121 404.7 0.0 2.9e-121 404.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF2024 PF09630.5 EMG49409.1 - 0.027 14.1 0.1 0.083 12.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) Peptidase_M28 PF04389.12 EMG49410.1 - 2.8e-34 118.4 0.1 6.6e-34 117.1 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 EMG49410.1 - 0.00035 20.1 0.0 0.0005 19.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EMG49410.1 - 0.0019 16.9 0.0 0.0049 15.6 0.0 1.5 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase P63C PF10546.4 EMG49410.1 - 0.042 13.7 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 P63C domain Gly-zipper_OmpA PF13436.1 EMG49411.1 - 0.1 12.2 6.2 0.11 12.1 4.3 1.0 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF533 PF04391.7 EMG49411.1 - 0.1 11.9 1.2 0.12 11.7 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) TraT PF05818.7 EMG49411.1 - 0.22 10.9 3.9 0.25 10.7 2.7 1.0 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Bacteriocin_IIc PF10439.4 EMG49411.1 - 1 9.5 6.9 1.3 9.2 4.8 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Rick_17kDa_Anti PF05433.10 EMG49411.1 - 1.5 8.5 15.0 10 5.8 10.8 1.9 1 1 1 2 2 2 0 Glycine zipper 2TM domain Ldh_1_N PF00056.18 EMG49412.1 - 2.4e-44 150.5 1.0 3.7e-44 149.9 0.7 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EMG49412.1 - 1.9e-33 115.6 0.0 3.4e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EMG49412.1 - 0.00043 19.0 0.0 0.0007 18.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EMG49412.1 - 0.08 13.2 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ATG27 PF09451.5 EMG49413.1 - 1.5e-72 244.0 0.9 1.7e-72 243.8 0.6 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 MTHFR PF02219.12 EMG49414.1 - 4.4e-107 357.4 0.0 6.3e-107 356.9 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ERCC4 PF02732.10 EMG49415.1 - 2.1e-25 89.1 8.3 3.1e-24 85.3 0.0 4.6 5 1 0 5 5 5 2 ERCC4 domain DUF4366 PF14283.1 EMG49416.1 - 0.14 11.5 0.4 1.2 8.4 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) RAP1 PF07218.6 EMG49416.1 - 1.6 6.7 12.7 2 6.4 8.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Porphobil_deam PF01379.15 EMG49417.1 - 1.1e-88 295.7 0.0 1.6e-88 295.2 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EMG49417.1 - 5.5e-19 68.0 0.1 9.3e-19 67.3 0.1 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain GATA PF00320.22 EMG49418.1 - 3.3e-08 32.7 6.9 3.3e-08 32.7 4.8 1.9 2 0 0 2 2 2 1 GATA zinc finger Suf PF05843.9 EMG49418.1 - 0.054 13.2 10.2 0.11 12.2 7.1 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 EMG49418.1 - 0.72 8.0 27.9 1.2 7.2 19.3 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ubiquitin PF00240.18 EMG49419.1 - 4.2e-22 77.3 0.2 6.2e-22 76.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EMG49419.1 - 5.1e-12 45.3 0.1 7.8e-12 44.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 EMG49419.1 - 8.5e-09 34.9 0.0 8.5e-09 34.9 0.0 2.7 3 0 0 3 3 3 1 UBA/TS-N domain DUF2407 PF10302.4 EMG49419.1 - 6.5e-07 29.4 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 EMG49419.1 - 9.4e-07 29.0 0.2 2.1e-06 27.8 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EMG49419.1 - 4.2e-06 26.6 0.1 7.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF4625 PF15418.1 EMG49419.1 - 0.0062 16.6 0.1 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4625) YukD PF08817.5 EMG49419.1 - 0.014 15.9 0.0 0.029 14.9 0.0 1.6 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD L27_2 PF09045.5 EMG49419.1 - 0.15 11.6 0.8 0.44 10.1 0.0 2.0 2 0 0 2 2 2 0 L27_2 MSA-2c PF12238.3 EMG49419.1 - 0.36 10.4 4.2 0.12 12.0 0.3 1.9 2 0 0 2 2 2 0 Merozoite surface antigen 2c XPC-binding PF09280.6 EMG49419.1 - 5.4 6.5 18.6 29 4.1 12.5 2.2 1 1 1 2 2 2 0 XPC-binding domain DUF3720 PF12517.3 EMG49419.1 - 8.8 7.0 13.9 58 4.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3720) TAF8_C PF10406.4 EMG49420.1 - 5.9e-23 80.6 1.6 5.9e-23 80.6 1.1 2.7 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 EMG49420.1 - 9.3e-05 22.0 0.0 0.00029 20.5 0.0 1.8 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.1 EMG49420.1 - 0.00011 22.3 0.0 0.00042 20.4 0.0 2.0 1 0 0 1 1 1 1 Kinetochore component CENP-S DUF1816 PF08846.5 EMG49420.1 - 0.0063 16.1 2.8 1.3 8.7 0.1 3.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1816) Glyco_transf_20 PF00982.16 EMG49421.1 - 1.6e-150 501.7 0.4 2.2e-150 501.2 0.3 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EMG49421.1 - 1.4e-15 56.8 0.0 2.8e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase CTK3 PF12243.3 EMG49422.1 - 1.3e-28 99.3 7.0 2.3e-28 98.5 3.2 2.3 3 0 0 3 3 3 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EMG49422.1 - 3.4e-24 84.6 4.0 8e-24 83.4 2.8 1.7 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus EF-hand_4 PF12763.2 EMG49422.1 - 0.36 10.5 5.9 6.7 6.5 0.4 3.0 3 1 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand eIF-1a PF01176.14 EMG49423.1 - 5.2e-27 93.0 0.5 7.4e-27 92.5 0.3 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Myb_DNA-bind_6 PF13921.1 EMG49423.1 - 0.084 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain DAGK_acc PF00609.14 EMG49423.1 - 0.099 12.7 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase accessory domain Mg_trans_NIPA PF05653.9 EMG49424.1 - 1.2e-110 369.1 14.8 1.4e-110 368.9 10.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EMG49424.1 - 1.3e-06 28.5 2.5 1.3e-06 28.5 1.7 3.0 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EMG49424.1 - 0.00064 19.7 7.7 0.00064 19.7 5.4 2.8 2 1 0 2 2 2 1 EamA-like transporter family DUF2937 PF11157.3 EMG49424.1 - 0.048 12.9 0.3 0.11 11.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) MARVEL PF01284.18 EMG49424.1 - 1.6 8.5 13.2 0.28 11.0 5.3 2.3 1 1 1 2 2 2 0 Membrane-associating domain DUF1282 PF06930.7 EMG49424.1 - 5.9 6.5 23.7 0.26 10.9 7.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1282) Gal4_dimer PF03902.8 EMG49425.1 - 1.1e-20 73.2 2.3 2.8e-20 71.9 1.6 1.7 1 0 0 1 1 1 1 Gal4-like dimerisation domain Zn_clus PF00172.13 EMG49425.1 - 3.2e-07 30.1 17.9 5.4e-07 29.4 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2797 PF10977.3 EMG49425.1 - 0.93 9.0 3.8 1.7 8.2 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) RabGAP-TBC PF00566.13 EMG49427.1 - 5.7e-48 163.2 4.0 5.7e-48 163.2 2.7 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain APG6 PF04111.7 EMG49427.1 - 0.0018 17.4 2.1 0.0018 17.4 1.5 3.0 2 1 1 3 3 3 1 Autophagy protein Apg6 DUF972 PF06156.8 EMG49427.1 - 0.0047 17.2 3.0 0.0047 17.2 2.1 4.0 2 1 2 4 4 4 1 Protein of unknown function (DUF972) Reo_sigmaC PF04582.7 EMG49427.1 - 0.0056 15.8 2.7 0.0056 15.8 1.9 1.9 2 0 0 2 2 2 1 Reovirus sigma C capsid protein bZIP_1 PF00170.16 EMG49427.1 - 0.18 11.7 11.3 0.32 10.9 0.7 3.8 3 0 0 3 3 3 0 bZIP transcription factor Filament PF00038.16 EMG49427.1 - 0.23 10.9 15.5 0.17 11.3 6.6 2.3 2 0 0 2 2 2 0 Intermediate filament protein FlaC_arch PF05377.6 EMG49427.1 - 0.51 10.2 8.1 0.42 10.5 0.9 3.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Seryl_tRNA_N PF02403.17 EMG49427.1 - 1.9 8.5 18.0 0.14 12.2 1.7 3.5 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Syntaxin-6_N PF09177.6 EMG49427.1 - 2.3 8.6 14.1 0.43 11.0 1.0 4.1 2 1 2 4 4 4 0 Syntaxin 6, N-terminal TPR_MLP1_2 PF07926.7 EMG49427.1 - 2.7 7.7 19.9 2.8 7.6 8.4 3.2 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DEAD PF00270.24 EMG49428.1 - 1.1e-21 77.0 0.0 6.2e-21 74.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.5 EMG49428.1 - 2.5e-21 75.3 0.2 6e-21 74.1 0.2 1.7 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.26 EMG49428.1 - 1.4e-19 69.7 0.0 1.7e-17 63.0 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_34 PF13872.1 EMG49428.1 - 0.13 10.9 0.1 1.7 7.2 0.1 2.1 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 UQ_con PF00179.21 EMG49429.1 - 1.2e-21 76.5 0.2 1.6e-21 76.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMG49429.1 - 1.2e-05 25.1 0.1 1.9e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 Prokaryotic E2 family B zf-CCCH PF00642.19 EMG49430.1 - 3.8e-21 74.2 14.9 3.8e-13 48.7 1.0 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EMG49430.1 - 0.0044 16.9 12.0 0.049 13.6 0.8 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type zf-H2C2_2 PF13465.1 EMG49431.1 - 1.2e-11 44.2 20.7 1.7e-07 31.1 2.3 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EMG49431.1 - 4.7e-08 32.9 16.0 0.00075 19.6 4.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMG49431.1 - 1.3e-05 25.1 14.8 0.0089 16.3 1.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger RPAP2_Rtr1 PF04181.8 EMG49431.1 - 0.039 14.0 1.2 0.069 13.2 0.6 1.6 1 1 0 1 1 1 0 Rtr1/RPAP2 family zf-C2H2_jaz PF12171.3 EMG49431.1 - 0.055 13.6 6.3 0.15 12.2 1.7 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EMG49431.1 - 0.072 13.2 5.8 0.12 12.5 4.0 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EMG49431.1 - 0.082 12.8 2.3 0.64 10.0 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Ogr_Delta PF04606.7 EMG49431.1 - 0.11 12.1 3.7 0.3 10.7 2.6 1.7 1 1 0 1 1 1 0 Ogr/Delta-like zinc finger DUF605 PF04652.11 EMG49431.1 - 3.1 7.0 16.4 3.8 6.8 11.4 1.2 1 0 0 1 1 1 0 Vta1 like DUF3554 PF12074.3 EMG49432.1 - 2e-38 132.7 17.4 3.2e-36 125.4 2.9 5.8 4 1 0 4 4 4 2 Domain of unknown function (DUF3554) HEAT PF02985.17 EMG49432.1 - 8.1e-32 106.4 11.0 0.019 15.0 0.0 14.5 15 0 0 15 15 15 8 HEAT repeat HEAT_EZ PF13513.1 EMG49432.1 - 2e-28 98.1 20.2 0.012 16.0 0.0 16.0 13 3 4 17 17 17 8 HEAT-like repeat HEAT_2 PF13646.1 EMG49432.1 - 1e-27 96.1 29.5 0.00044 20.4 0.0 15.0 9 2 5 15 15 15 9 HEAT repeats CLASP_N PF12348.3 EMG49432.1 - 3.4e-16 59.3 1.5 0.0016 17.8 0.0 8.8 7 1 2 9 9 9 6 CLASP N terminal Vac14_Fab1_bd PF12755.2 EMG49432.1 - 8.5e-14 51.7 0.1 0.025 14.9 0.0 8.4 8 1 1 9 9 9 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EMG49432.1 - 3.7e-13 49.7 8.3 0.013 15.3 0.0 9.3 7 2 1 8 8 8 2 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.4 EMG49432.1 - 0.0035 17.0 0.2 0.048 13.4 0.0 2.6 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Ipi1_N PF12333.3 EMG49432.1 - 0.0076 16.1 0.0 3 7.8 0.0 5.2 7 1 0 7 7 7 1 Rix1 complex component involved in 60S ribosome maturation Pkinase PF00069.20 EMG49433.1 - 1.6e-63 214.2 0.1 3.2e-63 213.2 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG49433.1 - 1.1e-37 129.5 0.0 1.4e-36 125.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase HAUS6_N PF14661.1 EMG49433.1 - 0.038 13.3 7.4 0.063 12.6 5.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Mago_nashi PF02792.9 EMG49433.1 - 0.072 12.7 0.1 0.072 12.7 0.1 1.8 2 0 0 2 2 2 0 Mago nashi protein Bacillus_HBL PF05791.6 EMG49433.1 - 0.19 11.0 5.4 0.53 9.6 3.4 1.9 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) V_ATPase_I PF01496.14 EMG49433.1 - 0.19 9.5 8.1 0.29 8.9 5.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.9 EMG49433.1 - 0.76 9.7 12.8 1.3 8.9 8.8 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4239 PF14023.1 EMG49433.1 - 0.93 8.8 2.5 2 7.7 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) IncA PF04156.9 EMG49433.1 - 3.8 7.0 15.6 6.1 6.3 10.8 1.4 1 0 0 1 1 1 0 IncA protein FH2 PF02181.18 EMG49434.1 - 1.6e-83 280.6 9.4 1.6e-83 280.6 6.5 2.7 2 1 1 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 EMG49434.1 - 1.1e-52 178.2 1.5 1.1e-52 178.2 1.0 4.0 3 1 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 EMG49434.1 - 5.2e-35 120.5 0.3 5.2e-35 120.5 0.2 3.7 4 0 0 4 4 4 1 Diaphanous GTPase-binding Domain Sugar_tr PF00083.19 EMG49435.1 - 4e-44 150.9 22.5 5.4e-44 150.5 15.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG49435.1 - 8.4e-10 37.8 14.8 8.4e-10 37.8 10.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MMS1_N PF10433.4 EMG49436.1 - 7.9e-115 383.8 6.8 1.5e-114 382.8 4.7 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PilJ PF13675.1 EMG49437.1 - 0.0053 17.0 0.5 0.006 16.8 0.4 1.1 1 0 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term TSC22 PF01166.13 EMG49437.1 - 0.045 13.7 1.4 0.045 13.7 1.0 1.8 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF1203 PF06718.6 EMG49437.1 - 0.11 12.2 0.2 0.15 11.9 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1203) Speriolin_N PF15058.1 EMG49437.1 - 0.21 11.4 0.6 0.25 11.2 0.4 1.1 1 0 0 1 1 1 0 Speriolin N terminus DUF724 PF05266.9 EMG49437.1 - 0.58 9.7 7.7 0.68 9.5 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TPD52 PF04201.10 EMG49437.1 - 0.69 9.6 6.3 0.56 9.9 3.7 1.3 1 1 0 1 1 1 0 Tumour protein D52 family bZIP_1 PF00170.16 EMG49437.1 - 0.77 9.7 7.7 5.4 7.0 5.3 2.0 1 1 0 1 1 1 0 bZIP transcription factor NYD-SP28_assoc PF14775.1 EMG49437.1 - 1.8 8.3 6.3 4.6 7.0 0.5 2.6 1 1 2 3 3 3 0 Sperm tail C-terminal domain zf-C4H2 PF10146.4 EMG49437.1 - 2.4 8.1 8.4 2.5 8.0 5.8 1.0 1 0 0 1 1 1 0 Zinc finger-containing protein Lip_prot_lig_C PF10437.4 EMG49437.1 - 2.9 7.6 6.0 0.24 11.1 0.4 1.8 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus DivIC PF04977.10 EMG49437.1 - 5.7 6.5 8.8 0.66 9.4 2.1 2.0 1 1 1 2 2 2 0 Septum formation initiator bZIP_2 PF07716.10 EMG49437.1 - 5.9 6.7 8.0 3.9 7.3 0.6 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Yip1 PF04893.12 EMG49438.1 - 9.6e-07 28.4 6.4 1.3e-06 28.0 4.4 1.2 1 0 0 1 1 1 1 Yip1 domain DUF3337 PF11816.3 EMG49439.1 - 1.2e-42 146.5 3.4 1.2e-42 146.5 2.4 2.2 2 1 2 4 4 4 1 Domain of unknown function (DUF3337) WD40 PF00400.27 EMG49439.1 - 6.1e-23 79.8 14.5 3e-07 30.0 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat CENP-S PF15630.1 EMG49440.1 - 6.8e-24 83.8 0.1 1.5e-23 82.7 0.0 1.5 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EMG49440.1 - 0.0046 16.2 0.0 0.0058 15.9 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T NBP1 PF08537.5 EMG49440.1 - 0.11 11.6 0.2 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Mitochondr_Som1 PF11093.3 EMG49441.1 - 4.5e-36 122.5 2.5 6e-36 122.1 1.7 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 BCIP PF13862.1 EMG49442.1 - 2.3e-64 216.4 6.8 3.1e-64 216.0 4.7 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein PCI PF01399.22 EMG49443.1 - 1.4e-10 41.4 0.5 1.4e-10 41.4 0.4 2.9 3 0 0 3 3 3 1 PCI domain MAD PF05557.8 EMG49444.1 - 5.1e-19 67.8 87.8 1.7e-18 66.1 60.9 1.6 1 1 0 1 1 1 1 Mitotic checkpoint protein PRP1_N PF06424.7 EMG49445.1 - 7.7e-31 107.1 0.6 7.7e-31 107.1 0.4 2.4 3 0 0 3 3 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EMG49445.1 - 2.7e-18 64.8 0.0 0.32 11.7 0.0 10.7 5 3 7 12 12 11 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMG49445.1 - 1.5e-12 47.6 2.0 0.0042 17.3 0.0 7.9 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMG49445.1 - 3e-10 40.5 0.0 0.00095 19.7 0.0 5.6 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMG49445.1 - 7e-09 35.2 7.7 0.011 15.3 0.0 6.6 5 1 3 8 8 7 3 TPR repeat TPR_2 PF07719.12 EMG49445.1 - 7.5e-07 28.5 4.9 9.4 6.4 0.0 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMG49445.1 - 3e-05 23.8 10.9 8.2 6.9 0.1 7.4 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMG49445.1 - 4.6e-05 22.8 5.7 0.62 9.9 0.1 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMG49445.1 - 0.0053 16.5 0.0 0.42 10.5 0.0 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMG49445.1 - 0.0087 15.9 1.3 7.4 6.5 0.0 4.7 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMG49445.1 - 0.034 14.6 1.9 88 3.8 0.1 5.7 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMG49445.1 - 4.1 7.1 7.5 13 5.5 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat CAF1C_H4-bd PF12265.3 EMG49446.1 - 7.7e-19 67.3 0.0 2.1e-18 65.9 0.0 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 EMG49446.1 - 9.6e-17 60.1 20.4 4.5e-07 29.5 0.0 5.9 7 0 0 7 7 7 3 WD domain, G-beta repeat Tom37_C PF11801.3 EMG49446.1 - 0.063 13.1 4.6 0.31 10.9 0.6 2.3 2 0 0 2 2 2 0 Tom37 C-terminal domain ELH PF02323.10 EMG49446.1 - 0.071 12.2 4.6 0.085 11.9 0.1 2.3 2 0 0 2 2 2 0 Egg-laying hormone precursor TFIIF_alpha PF05793.7 EMG49446.1 - 4.3 5.5 28.3 5.5 5.2 14.5 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Myc_N PF01056.13 EMG49446.1 - 7.5 5.6 15.8 0.68 9.0 0.3 2.3 2 0 0 2 2 2 0 Myc amino-terminal region DUF3449 PF11931.3 EMG49446.1 - 9.1 5.7 13.0 10 5.5 4.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) Pro_isomerase PF00160.16 EMG49447.1 - 1.4e-43 148.7 1.2 2.4e-43 148.0 0.5 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Transketolase_N PF00456.16 EMG49447.1 - 0.06 12.1 0.4 0.1 11.4 0.2 1.3 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain EAF PF09816.4 EMG49448.1 - 5.4e-26 90.6 1.4 5.4e-26 90.6 1.0 2.1 3 0 0 3 3 3 1 RNA polymerase II transcription elongation factor DUF1054 PF06335.7 EMG49448.1 - 0.0069 16.0 3.7 0.72 9.4 0.3 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1054) BAR PF03114.13 EMG49449.1 - 1.1e-41 142.8 9.9 1.4e-41 142.5 6.9 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 EMG49449.1 - 0.022 14.1 0.5 0.022 14.1 0.3 2.4 3 0 0 3 3 3 0 Arfaptin-like domain Uds1 PF15456.1 EMG49449.1 - 0.11 12.4 6.7 2.6 8.0 0.1 2.6 3 0 0 3 3 3 0 Up-regulated During Septation DUF3150 PF11348.3 EMG49449.1 - 0.26 10.3 4.0 0.18 10.8 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3150) NPV_P10 PF05531.7 EMG49449.1 - 0.31 11.3 9.4 0.89 9.8 0.7 3.3 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF2730 PF10805.3 EMG49449.1 - 0.37 10.5 3.3 0.31 10.8 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) Mt_ATP-synt_D PF05873.7 EMG49449.1 - 1.7 8.2 10.6 1.1 8.8 1.1 3.2 1 1 2 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) Fib_alpha PF08702.5 EMG49449.1 - 5.3 7.1 17.9 0.72 9.9 4.0 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family UCH_1 PF13423.1 EMG49450.1 - 1.4e-50 172.4 0.6 2.2e-50 171.7 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 EMG49451.1 - 2.2e-30 103.4 1.9 1.2e-07 31.3 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EMG49451.1 - 0.00068 18.5 0.1 0.16 10.7 0.0 2.3 2 0 0 2 2 2 2 Coatomer WD associated region ELO PF01151.13 EMG49452.1 - 3.1e-59 200.2 27.6 4.2e-59 199.8 19.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family RNA_pol_Rpb5_C PF01191.14 EMG49453.1 - 2.1e-33 113.7 1.4 2.3e-33 113.6 0.3 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EMG49453.1 - 2.9e-32 110.9 0.2 4.8e-32 110.2 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain SH3_2 PF07653.12 EMG49453.1 - 0.14 11.7 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Prp19_bind PF06991.6 EMG49454.1 - 1.8e-12 47.1 18.1 1.2e-11 44.4 12.5 1.8 1 1 0 1 1 1 1 Splicing factor, Prp19-binding domain GIT_SHD PF08518.6 EMG49455.1 - 1e-26 91.9 4.8 3.8e-14 51.7 0.7 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT IncA PF04156.9 EMG49455.1 - 0.0049 16.4 14.7 0.0049 16.4 10.2 4.7 4 2 2 6 6 6 1 IncA protein Cwf_Cwc_15 PF04889.7 EMG49456.1 - 2.5e-21 76.4 35.2 1.5e-08 34.6 4.2 3.0 1 1 2 3 3 3 3 Cwf15/Cwc15 cell cycle control protein DUF740 PF05340.7 EMG49456.1 - 0.0015 16.9 16.6 0.0018 16.7 11.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF740) DUF3450 PF11932.3 EMG49456.1 - 0.056 12.6 4.4 0.079 12.2 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Merozoite_SPAM PF07133.6 EMG49456.1 - 2.1 8.2 34.2 0.37 10.6 21.0 1.6 1 1 0 2 2 2 0 Merozoite surface protein (SPAM) APG6 PF04111.7 EMG49456.1 - 8.3 5.3 16.1 13 4.7 11.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Hyphal_reg_CWP PF11765.3 EMG49457.1 - 1e-57 195.4 8.5 1e-57 195.4 5.9 1.8 2 0 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal DEAD PF00270.24 EMG49458.1 - 6.1e-42 142.9 0.7 2.3e-41 141.1 0.4 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG49458.1 - 8.2e-27 92.8 0.1 4.8e-26 90.4 0.1 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EMG49458.1 - 0.055 13.6 1.1 0.43 10.7 0.7 2.3 1 1 0 1 1 1 0 AAA domain Ribonucleas_3_3 PF14622.1 EMG49459.1 - 2.6e-26 92.0 0.0 3.8e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Serinc PF03348.10 EMG49461.1 - 4.3e-162 539.7 17.9 4.9e-162 539.5 12.4 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF1077 PF06417.7 EMG49461.1 - 0.49 9.7 5.2 2.3 7.5 3.6 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1077) DUF3566 PF12089.3 EMG49461.1 - 2.9 7.9 9.8 0.073 13.0 1.5 2.3 2 1 0 2 2 2 0 Transmembrane domain of unknown function (DUF3566) ATP-synt_G PF04718.10 EMG49462.1 - 1.6e-20 73.6 0.2 2e-20 73.3 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit Rax2 PF12768.2 EMG49463.1 - 2.8e-91 305.6 41.4 3.4e-88 295.5 1.2 5.1 4 2 1 5 5 5 3 Cortical protein marker for cell polarity VTC PF09359.5 EMG49463.1 - 0.019 13.9 0.5 0.85 8.5 0.0 2.4 2 0 0 2 2 2 0 VTC domain TRAPPC-Trs85 PF12739.2 EMG49464.1 - 2.2e-111 372.4 5.0 2.2e-111 372.4 3.5 1.4 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF1751 PF08551.5 EMG49465.1 - 1.2e-23 83.3 3.5 1.2e-23 83.3 2.4 2.2 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EMG49465.1 - 2.8e-06 27.4 9.5 4.3e-06 26.7 6.6 1.3 1 0 0 1 1 1 1 Rhomboid family RseC_MucC PF04246.7 EMG49465.1 - 0.17 11.4 0.2 0.44 10.1 0.1 1.6 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC MCM PF00493.18 EMG49467.1 - 5.9e-139 462.4 0.1 8.4e-139 461.9 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EMG49467.1 - 1.1e-21 77.5 1.2 1e-20 74.4 0.6 2.8 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EMG49467.1 - 5.5e-06 25.6 0.0 0.00022 20.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EMG49467.1 - 1.3e-05 24.9 0.0 5.2e-05 22.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EMG49467.1 - 0.00065 19.3 0.0 0.0058 16.2 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EMG49467.1 - 0.056 12.9 0.3 3.3 7.1 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain TFIIS_C PF01096.13 EMG49467.1 - 4.1 7.1 6.0 14 5.4 0.3 3.1 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) IncA PF04156.9 EMG49467.1 - 4.3 6.8 6.9 0.34 10.4 0.1 2.3 3 0 0 3 3 3 0 IncA protein Rad51 PF08423.6 EMG49468.1 - 2.2e-127 423.2 0.3 3.1e-127 422.8 0.0 1.3 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 EMG49468.1 - 2e-10 40.4 0.0 2.8e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EMG49468.1 - 2.3e-10 40.0 0.0 3e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EMG49468.1 - 2.2e-09 36.7 0.0 4.9e-09 35.6 0.0 1.6 2 1 0 2 2 2 1 KaiC HHH_5 PF14520.1 EMG49468.1 - 6.7e-07 29.3 1.8 1e-06 28.7 0.3 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain DUF128 PF01995.11 EMG49468.1 - 0.0023 16.9 0.1 0.0035 16.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF128 RNA_pol_A_CTD PF03118.10 EMG49468.1 - 0.0025 17.1 0.3 0.0057 16.0 0.2 1.6 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain AAA_22 PF13401.1 EMG49468.1 - 0.015 15.3 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PAXNEB PF05625.6 EMG49469.1 - 3.4e-119 397.9 1.4 4.1e-119 397.6 1.0 1.0 1 0 0 1 1 1 1 PAXNEB protein BNR PF02012.15 EMG49471.1 - 3.2e-13 47.3 37.3 0.029 14.1 0.2 11.4 12 0 0 12 12 12 6 BNR/Asp-box repeat BNR_2 PF13088.1 EMG49471.1 - 2.2e-08 33.7 0.2 0.088 12.0 0.0 5.6 4 3 0 4 4 4 2 BNR repeat-like domain PSII_BNR PF14870.1 EMG49471.1 - 3.1e-07 29.7 0.1 0.068 12.1 0.0 4.8 5 0 0 5 5 5 3 Photosynthesis system II assembly factor YCF48 Ribosomal_L27e PF01777.13 EMG49472.1 - 5e-27 93.8 11.3 1.4e-26 92.3 7.8 1.8 1 0 0 1 1 1 1 Ribosomal L27e protein family tRNA-synt_1b PF00579.20 EMG49472.1 - 3e-16 59.4 0.4 2.2e-10 40.1 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (W and Y) KOW PF00467.24 EMG49472.1 - 0.0014 18.2 1.3 0.004 16.8 0.9 1.8 1 0 0 1 1 1 1 KOW motif Pkinase PF00069.20 EMG49473.1 - 2.9e-65 220.0 0.1 2.9e-65 220.0 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG49473.1 - 1.9e-34 118.9 0.0 2.9e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG49473.1 - 1.8e-07 30.3 0.0 1.3e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMG49473.1 - 4.7e-06 25.8 0.0 9.8e-06 24.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMG49473.1 - 0.0056 16.4 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EMG49473.1 - 0.0092 15.3 0.3 0.021 14.1 0.2 1.6 1 0 0 1 1 1 1 RIO1 family RNase_T PF00929.19 EMG49474.1 - 3.8e-21 76.0 0.0 1.4e-20 74.2 0.0 2.1 1 0 0 1 1 1 1 Exonuclease RasGAP PF00616.14 EMG49475.1 - 5.4e-38 130.6 0.5 5.4e-38 130.6 0.3 3.4 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase DUF1518 PF07469.7 EMG49476.1 - 0.41 10.8 5.6 1 9.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1518) Brix PF04427.13 EMG49477.1 - 9.2e-42 142.8 1.1 1.2e-41 142.4 0.7 1.2 1 0 0 1 1 1 1 Brix domain DUF2611 PF11022.3 EMG49478.1 - 1.2e-22 79.7 0.0 1.3e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) RNB PF00773.14 EMG49480.1 - 3.6e-94 315.6 0.1 5.6e-94 315.0 0.1 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EMG49480.1 - 3.5e-17 62.7 0.5 8.6e-17 61.4 0.4 1.7 1 0 0 1 1 1 1 PIN domain DHBP_synthase PF00926.14 EMG49481.1 - 3.6e-82 274.2 0.0 4e-82 274.1 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Multi_ubiq PF14452.1 EMG49481.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Multiubiquitin Prenyltransf PF01255.14 EMG49482.1 - 7.2e-75 250.9 0.6 1.7e-74 249.7 0.0 1.8 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase Vma12 PF11712.3 EMG49482.1 - 2.5e-41 140.7 1.1 5.3e-41 139.6 0.8 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase ATP_synt_I PF03899.10 EMG49482.1 - 0.01 15.9 4.9 0.02 15.0 3.4 1.4 1 0 0 1 1 1 0 ATP synthase I chain Ribosomal_L50 PF10501.4 EMG49483.1 - 4.2e-28 97.5 0.0 1.9e-27 95.4 0.0 2.0 2 0 0 2 2 2 1 Ribosomal subunit 39S Rhomboid PF01694.17 EMG49484.1 - 4.6e-31 107.8 15.7 1.4e-30 106.2 10.9 1.8 1 0 0 1 1 1 1 Rhomboid family PIG-P PF08510.7 EMG49484.1 - 6.6 6.3 8.1 0.81 9.3 0.1 3.5 4 0 0 4 4 4 0 PIG-P E1-E2_ATPase PF00122.15 EMG49485.1 - 1.3e-50 171.6 0.0 3.2e-50 170.3 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EMG49485.1 - 3.5e-40 138.6 0.3 7.1e-40 137.7 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EMG49485.1 - 2.8e-19 69.0 5.4 1.9e-07 31.1 0.1 5.1 4 1 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 EMG49485.1 - 3.7e-18 66.3 0.0 7.8e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMG49485.1 - 0.0067 16.0 6.8 0.24 10.9 0.0 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase tRNA_SAD PF07973.9 EMG49486.1 - 2.3e-11 43.3 0.1 7.3e-11 41.7 0.0 2.0 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 EMG49486.1 - 2.9e-07 29.1 0.0 4.3e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) TBPIP PF07106.8 EMG49486.1 - 0.0059 16.1 0.4 0.015 14.8 0.3 1.6 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Penicillinase_R PF03965.11 EMG49486.1 - 0.011 15.8 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Penicillinase repressor AAA_32 PF13654.1 EMG49486.1 - 0.12 11.0 0.0 0.2 10.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain CBS PF00571.23 EMG49487.1 - 3.4e-37 125.9 10.1 5.6e-10 38.8 0.0 5.3 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 EMG49487.1 - 4.4e-08 32.6 0.1 9e-08 31.6 0.1 1.5 1 0 0 1 1 1 1 PB1 domain PP2C PF00481.16 EMG49488.1 - 7.2e-66 222.1 0.1 6.5e-65 219.0 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EMG49488.1 - 0.064 12.9 0.0 0.21 11.2 0.0 2.0 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Ustilago_mating PF05722.7 EMG49488.1 - 1.9 7.7 7.9 2.8 7.1 5.5 1.2 1 0 0 1 1 1 0 Ustilago B locus mating-type protein RAP1 PF07218.6 EMG49488.1 - 2.8 5.9 8.9 3.6 5.5 6.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) F-box-like PF12937.2 EMG49489.1 - 2.7e-06 27.0 0.2 6.8e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like DnaJ PF00226.26 EMG49490.1 - 7.7e-18 64.0 1.4 7.7e-18 64.0 0.9 3.3 3 0 0 3 3 3 1 DnaJ domain PigN PF04987.9 EMG49491.1 - 9.2e-138 459.5 41.7 1.3e-137 459.0 28.9 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) IGPS PF00218.16 EMG49491.1 - 9.2e-79 264.0 0.1 1.4e-78 263.5 0.1 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 EMG49491.1 - 1.4e-45 155.0 0.0 3.2e-45 153.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Phosphodiest PF01663.17 EMG49491.1 - 2.5e-12 46.8 0.0 2.4e-09 36.9 0.0 2.5 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EMG49491.1 - 1.3e-08 34.3 0.0 5.2e-08 32.4 0.0 1.8 1 1 1 2 2 2 1 Sulfatase Peptidase_C26 PF07722.8 EMG49491.1 - 1.9e-06 27.4 0.0 3.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 Metalloenzyme PF01676.13 EMG49491.1 - 5.3e-06 26.0 0.0 1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily GlutR_dimer PF00745.15 EMG49491.1 - 0.07 13.0 0.3 0.14 12.1 0.2 1.5 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain MFS_1 PF07690.11 EMG49492.1 - 6.5e-35 120.4 33.9 6.5e-35 120.4 23.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMG49492.1 - 8.5e-06 24.2 5.7 1.4e-05 23.5 4.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EMG49492.1 - 0.00056 18.1 4.7 0.00085 17.5 3.2 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector AAA_22 PF13401.1 EMG49493.1 - 6e-12 45.8 0.1 2e-11 44.1 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EMG49493.1 - 4e-11 43.2 0.1 1e-10 41.9 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMG49493.1 - 1.3e-10 41.5 0.1 3.7e-10 40.0 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.1 EMG49493.1 - 0.00022 20.8 0.8 0.00066 19.3 0.3 1.9 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 EMG49493.1 - 0.00076 18.5 0.3 0.98 8.3 0.0 2.6 1 1 1 2 2 2 2 KAP family P-loop domain Sigma54_activat PF00158.21 EMG49493.1 - 0.0014 18.1 0.4 0.05 13.0 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain T2SE PF00437.15 EMG49493.1 - 0.0022 16.9 0.2 0.0056 15.6 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.1 EMG49493.1 - 0.0022 17.6 0.0 0.0082 15.8 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 EMG49493.1 - 0.0059 16.5 0.9 0.15 11.9 0.1 2.7 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 EMG49493.1 - 0.0093 14.9 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EMG49493.1 - 0.014 15.0 0.3 0.073 12.7 0.2 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 EMG49493.1 - 0.034 14.2 0.1 0.13 12.2 0.1 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF2075 PF09848.4 EMG49493.1 - 0.035 13.0 0.2 0.11 11.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 EMG49493.1 - 0.052 13.0 1.2 1.3 8.5 0.3 2.4 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_2 PF07724.9 EMG49493.1 - 0.061 13.2 0.0 2.9 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Cdc6_C PF09079.6 EMG49493.1 - 0.063 13.0 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 CDC6, C terminal Myb_DNA-binding PF00249.26 EMG49494.1 - 3.1e-14 52.7 0.0 1.6e-07 31.2 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain CDC45 PF02724.9 EMG49494.1 - 0.049 11.6 12.4 0.11 10.5 8.6 1.5 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_S9 PF00380.14 EMG49495.1 - 5.6e-39 133.1 0.1 1e-38 132.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF-hand_4 PF12763.2 EMG49496.1 - 6.1e-33 112.6 0.0 2.4e-11 43.2 0.1 3.7 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.26 EMG49496.1 - 4.9e-11 42.1 0.4 1.3e-10 40.8 0.3 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Macoilin PF09726.4 EMG49496.1 - 6.4e-05 21.4 19.7 6.4e-05 21.4 13.7 3.1 3 1 0 3 3 2 1 Transmembrane protein EF-hand_7 PF13499.1 EMG49496.1 - 7.3e-05 22.8 0.0 0.3 11.2 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMG49496.1 - 0.0022 17.7 0.0 0.31 11.0 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain CUE PF02845.11 EMG49496.1 - 0.0062 16.0 0.1 0.015 14.7 0.0 1.7 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.1 EMG49496.1 - 0.0066 15.9 0.2 0.014 14.9 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain DUF4201 PF13870.1 EMG49496.1 - 0.038 13.4 31.1 0.011 15.2 10.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) MADF_DNA_bdg PF10545.4 EMG49496.1 - 0.042 14.0 0.5 0.12 12.5 0.4 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Gly-zipper_OmpA PF13436.1 EMG49496.1 - 0.21 11.2 4.6 0.052 13.2 0.3 2.2 2 0 0 2 2 1 0 Glycine-zipper containing OmpA-like membrane domain Reo_sigmaC PF04582.7 EMG49496.1 - 0.46 9.5 20.3 1 8.4 8.3 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EMG49496.1 - 1.8 8.4 41.3 30 4.4 17.3 3.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG2 PF06148.6 EMG49496.1 - 2.7 7.8 23.5 2.3 8.0 3.1 3.2 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TauD PF02668.11 EMG49497.1 - 7.6e-44 150.3 0.3 9.9e-44 149.9 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Zn_clus PF00172.13 EMG49498.1 - 0.00023 21.0 13.9 0.00023 21.0 9.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phage_1_1 PF08200.6 EMG49498.1 - 7.8 6.7 6.5 0.51 10.5 0.8 1.8 2 0 0 2 2 2 0 Bacteriophage 1.1 Protein SH3_1 PF00018.23 EMG49499.1 - 1.9e-08 33.5 0.0 4.8e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMG49499.1 - 6.8e-06 25.5 0.0 2.7e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain Plasmodium_Vir PF05795.6 EMG49499.1 - 0.0016 17.7 0.9 0.0024 17.1 0.6 1.4 1 0 0 1 1 1 1 Plasmodium vivax Vir protein DUF4448 PF14610.1 EMG49499.1 - 0.0034 16.8 0.2 0.027 13.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) SH3_3 PF08239.6 EMG49499.1 - 0.0065 16.6 0.2 0.025 14.7 0.0 2.1 2 0 0 2 2 1 1 Bacterial SH3 domain DUF1183 PF06682.7 EMG49499.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) SH3_2 PF07653.12 EMG49499.1 - 0.015 14.8 0.0 0.049 13.1 0.0 2.0 2 1 0 2 2 2 0 Variant SH3 domain Sarcoglycan_2 PF05510.8 EMG49499.1 - 0.021 13.1 0.0 0.071 11.3 0.0 1.7 1 1 1 2 2 2 0 Sarcoglycan alpha/epsilon TMEM154 PF15102.1 EMG49499.1 - 0.059 13.0 6.6 0.43 10.2 4.6 2.4 1 1 0 1 1 1 0 TMEM154 protein family DUF202 PF02656.10 EMG49499.1 - 0.069 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Ctr PF04145.10 EMG49499.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 Ctr copper transporter family Abhydrolase_1 PF00561.15 EMG49501.1 - 6.3e-17 61.9 0.0 5.5e-16 58.8 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMG49501.1 - 3.5e-08 33.6 0.0 1.6e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EMG49501.1 - 0.00018 21.0 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase PLDc PF00614.17 EMG49502.1 - 2.2e-15 55.8 0.3 3e-08 33.1 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EMG49502.1 - 6e-12 45.4 0.6 9.9e-08 31.7 0.2 2.8 2 1 0 2 2 2 2 PLD-like domain DOPA_dioxygen PF08883.6 EMG49503.1 - 4.3e-36 123.1 0.2 4.8e-36 122.9 0.1 1.0 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family ACP PF06857.6 EMG49503.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) VanZ PF04892.7 EMG49504.1 - 1.8e-08 34.4 2.7 2.5e-08 33.9 1.9 1.2 1 0 0 1 1 1 1 VanZ like family PBP1_TM PF14812.1 EMG49504.1 - 0.41 10.9 5.1 0.6 10.4 3.5 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MMR_HSR1 PF01926.18 EMG49505.1 - 8.7e-16 57.9 0.0 2.2e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMG49505.1 - 3e-07 30.0 0.1 9.4e-07 28.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EMG49505.1 - 1.2e-06 27.7 0.0 2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EMG49505.1 - 3.1e-06 26.4 0.1 2.3e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.18 EMG49505.1 - 3.4e-06 26.9 3.3 0.038 13.8 0.0 3.2 3 1 1 4 4 4 2 Dynamin family SRPRB PF09439.5 EMG49505.1 - 4.6e-06 25.9 0.4 1.9e-05 23.9 0.0 2.0 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EMG49505.1 - 9.4e-05 21.7 0.0 0.00016 21.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.13 EMG49505.1 - 0.0021 17.1 0.1 0.0049 15.9 0.0 1.7 1 0 0 1 1 1 1 Septin Miro PF08477.8 EMG49505.1 - 0.0025 18.2 0.1 0.013 16.0 0.1 2.3 1 1 0 1 1 1 1 Miro-like protein MobB PF03205.9 EMG49505.1 - 0.12 12.0 1.4 0.29 10.8 0.0 2.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Aa_trans PF01490.13 EMG49506.1 - 1.7e-85 287.0 29.8 2.1e-85 286.6 20.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EMG49506.1 - 0.084 11.3 40.7 0.0046 15.5 23.7 1.8 1 1 1 2 2 2 0 Amino acid permease ATG27 PF09451.5 EMG49506.1 - 0.23 10.6 4.2 0.079 12.1 0.6 1.9 2 0 0 2 2 2 0 Autophagy-related protein 27 PAP2 PF01569.16 EMG49507.1 - 1e-22 80.1 3.0 1e-22 80.1 2.1 1.7 2 1 0 2 2 2 1 PAP2 superfamily ABC2_membrane_4 PF12730.2 EMG49507.1 - 0.17 11.0 0.1 0.17 11.0 0.1 2.3 2 1 0 2 2 2 0 ABC-2 family transporter protein Chromate_transp PF02417.10 EMG49507.1 - 6.3 6.3 7.9 1.1 8.8 1.0 2.4 3 0 0 3 3 3 0 Chromate transporter DUF1700 PF08006.6 EMG49507.1 - 8.8 5.5 7.0 5.7 6.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Sel1 PF08238.7 EMG49508.1 - 6.3e-17 61.6 8.3 0.004 17.7 0.0 7.2 6 1 0 6 6 6 4 Sel1 repeat TPR_11 PF13414.1 EMG49508.1 - 4.1e-08 32.7 5.7 3.9e-07 29.6 0.3 3.5 2 1 2 4 4 4 1 TPR repeat TPR_1 PF00515.23 EMG49508.1 - 0.00028 20.3 10.1 0.015 14.8 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMG49508.1 - 0.00053 19.7 6.1 1.1 9.2 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMG49508.1 - 0.00066 19.6 0.5 0.025 14.7 0.0 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMG49508.1 - 0.00097 18.7 0.5 1.6 8.7 0.2 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMG49508.1 - 0.0012 19.4 0.0 0.028 15.0 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMG49508.1 - 0.019 14.8 9.7 0.14 12.1 0.1 5.4 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMG49508.1 - 0.022 14.5 13.4 1.2 9.0 0.0 4.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Nucleoplasmin PF03066.10 EMG49508.1 - 0.034 13.6 15.7 0.08 12.4 3.6 2.6 2 0 0 2 2 2 0 Nucleoplasmin TPR_14 PF13428.1 EMG49508.1 - 0.063 13.9 0.1 40 5.2 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat ASCH PF04266.9 EMG49508.1 - 0.12 12.7 0.3 0.39 11.1 0.2 1.9 1 0 0 1 1 1 0 ASCH domain NOA36 PF06524.7 EMG49508.1 - 0.13 11.4 16.1 0.0091 15.2 3.8 2.4 2 0 0 2 2 2 0 NOA36 protein Sigma70_ner PF04546.8 EMG49508.1 - 0.83 9.2 14.7 0.49 9.9 2.5 2.7 2 0 0 2 2 2 0 Sigma-70, non-essential region ADH_zinc_N PF00107.21 EMG49510.1 - 4.9e-07 29.3 0.0 8.2e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMG49510.1 - 0.00014 21.6 0.1 0.00027 20.6 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EMG49510.1 - 0.014 16.2 0.0 0.16 12.8 0.0 2.1 1 1 1 2 2 2 0 Zinc-binding dehydrogenase GATA PF00320.22 EMG49511.1 - 1.1e-15 56.6 4.5 2.8e-15 55.3 3.1 1.8 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 EMG49511.1 - 0.012 14.8 0.7 0.032 13.5 0.5 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding DUF1774 PF08611.5 EMG49512.1 - 4.8e-31 106.7 6.5 4.8e-31 106.7 4.5 2.7 3 0 0 3 3 3 1 Fungal protein of unknown function (DUF1774) Pyridoxal_deC PF00282.14 EMG49513.1 - 1.7e-56 191.3 0.0 2.5e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EMG49513.1 - 3.5e-07 29.3 0.1 7.5e-07 28.2 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V YebO PF13974.1 EMG49513.1 - 0.51 10.1 2.2 0.71 9.7 0.7 1.8 2 0 0 2 2 2 0 YebO-like protein NAC PF01849.13 EMG49514.1 - 2.4e-18 65.3 0.0 5.3e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 NAC domain DUF3860 PF12976.2 EMG49514.1 - 0.072 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) MFS_1 PF07690.11 EMG49515.1 - 3.7e-16 58.7 22.2 3.8e-10 39.0 5.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 EMG49515.1 - 6.5e-11 41.9 11.0 6.5e-11 41.9 7.7 2.3 1 1 0 2 2 2 2 Nodulin-like PUCC PF03209.10 EMG49515.1 - 0.00077 18.2 2.7 0.00077 18.2 1.9 2.2 2 0 0 2 2 2 1 PUCC protein ApoO PF09769.4 EMG49516.1 - 1.4e-40 138.6 0.0 3.5e-40 137.3 0.0 1.6 2 0 0 2 2 2 1 Apolipoprotein O Ku PF02735.11 EMG49517.1 - 6.5e-18 64.8 1.9 1.3e-12 47.5 0.0 3.7 3 1 0 3 3 3 2 Ku70/Ku80 beta-barrel domain Spore_II_R PF09551.5 EMG49517.1 - 0.26 11.3 3.3 0.86 9.6 2.3 1.9 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) Ku_C PF03730.9 EMG49517.1 - 3.3 8.2 27.6 0.052 14.0 5.8 5.1 5 1 0 5 5 5 0 Ku70/Ku80 C-terminal arm Thymidylate_kin PF02223.12 EMG49518.1 - 1e-39 135.8 0.0 6.7e-39 133.1 0.0 1.9 1 1 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.5 EMG49518.1 - 0.00087 18.5 0.0 0.0018 17.5 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 EMG49518.1 - 0.0013 19.0 0.0 0.0039 17.5 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 EMG49518.1 - 0.08 12.8 0.2 0.29 11.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain ApbA_C PF08546.6 EMG49519.1 - 0.00042 20.3 0.0 0.00075 19.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Atg14 PF10186.4 EMG49519.1 - 0.93 8.3 18.7 1.9 7.3 12.9 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AA_permease_2 PF13520.1 EMG49520.1 - 6.3e-78 262.2 52.1 7.9e-78 261.8 36.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMG49520.1 - 2e-18 65.9 45.9 2.8e-18 65.5 31.8 1.1 1 0 0 1 1 1 1 Amino acid permease KH_1 PF00013.24 EMG49521.1 - 7.1e-66 217.7 46.6 1.9e-11 43.3 0.2 11.6 12 0 0 12 12 12 8 KH domain KH_3 PF13014.1 EMG49521.1 - 1.3e-47 158.6 30.1 1.7e-08 33.9 0.6 10.3 10 0 0 10 10 10 7 KH domain SLS PF14611.1 EMG49521.1 - 2.3e-08 33.7 24.9 0.056 12.8 1.5 7.2 4 2 4 8 8 8 4 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.1 EMG49521.1 - 5.8e-06 25.8 7.4 1.3 8.6 0.1 5.9 5 1 0 5 5 5 2 KH domain KH_2 PF07650.12 EMG49521.1 - 7.8e-06 25.3 18.4 0.062 12.8 0.1 6.7 6 0 0 6 6 6 4 KH domain Smg4_UPF3 PF03467.10 EMG49523.1 - 5.8e-13 49.2 9.4 5.8e-13 49.2 6.5 2.4 1 1 2 3 3 3 1 Smg-4/UPF3 family MKT1_C PF12246.3 EMG49523.1 - 0.0036 16.3 0.7 0.0087 15.0 0.5 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication PCI PF01399.22 EMG49524.1 - 1e-06 28.9 2.0 5.9e-06 26.5 1.4 2.0 1 1 0 1 1 1 1 PCI domain DUF605 PF04652.11 EMG49525.1 - 3.5e-71 240.6 13.3 4.5e-71 240.2 9.2 1.1 1 0 0 1 1 1 1 Vta1 like PH PF00169.24 EMG49526.1 - 4.5e-07 30.0 0.1 9.7e-05 22.5 0.0 2.7 2 0 0 2 2 2 2 PH domain Aa_trans PF01490.13 EMG49528.1 - 1.3e-83 280.7 36.8 1.6e-83 280.5 25.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EMG49528.1 - 4.4 5.7 43.5 16 3.8 30.2 1.9 1 1 0 1 1 1 0 Amino acid permease LRR_8 PF13855.1 EMG49529.1 - 3.7e-07 29.7 26.1 0.00014 21.5 1.3 6.6 5 3 1 6 6 6 2 Leucine rich repeat LRR_4 PF12799.2 EMG49529.1 - 5.7e-06 25.8 38.2 0.00064 19.2 2.1 7.7 4 3 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EMG49529.1 - 2e-05 24.0 24.1 0.13 12.5 0.1 9.4 9 3 0 9 9 9 2 Leucine rich repeat LRR_1 PF00560.28 EMG49529.1 - 0.0019 17.9 19.4 0.052 13.5 0.1 7.3 6 3 2 8 8 8 2 Leucine Rich Repeat hSac2 PF12456.3 EMG49529.1 - 0.036 13.4 0.3 0.39 10.1 0.1 2.4 1 1 1 2 2 2 0 Inositol phosphatase Xylo_C PF12529.3 EMG49529.1 - 0.082 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Xylosyltransferase C terminal LRR_6 PF13516.1 EMG49529.1 - 0.67 10.2 26.6 1.9 8.7 0.1 8.1 9 3 0 9 9 9 0 Leucine Rich repeat FNIP PF05725.7 EMG49529.1 - 8.9 6.3 16.6 6.5 6.7 1.1 5.5 5 1 1 6 6 6 0 FNIP Repeat LRR_4 PF12799.2 EMG49530.1 - 2.6e-06 26.9 3.7 0.078 12.6 0.0 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG49530.1 - 0.0066 16.1 4.5 0.16 11.7 0.5 3.2 2 1 0 2 2 2 1 Leucine rich repeat DUF2577 PF10844.3 EMG49530.1 - 0.1 12.6 0.0 0.12 12.4 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2577) LRR_6 PF13516.1 EMG49530.1 - 0.21 11.7 3.5 64 4.0 0.1 3.9 3 2 0 3 3 3 0 Leucine Rich repeat LRR_7 PF13504.1 EMG49530.1 - 0.66 10.4 2.8 28 5.5 0.0 4.0 2 1 0 2 2 2 0 Leucine rich repeat CMD PF02627.15 EMG49531.1 - 0.0039 16.9 0.0 0.013 15.3 0.0 1.7 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Med10 PF09748.4 EMG49532.1 - 2.2e-40 137.4 0.4 2.5e-40 137.2 0.2 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Flagellin_N PF00669.15 EMG49532.1 - 0.17 11.6 2.2 5.5 6.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF2217 PF10265.4 EMG49533.1 - 1.5 7.5 10.8 1.8 7.2 7.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Kinesin PF00225.18 EMG49534.1 - 8.7e-103 343.5 6.8 1.7e-102 342.6 4.7 1.4 1 0 0 1 1 1 1 Kinesin motor domain Fib_alpha PF08702.5 EMG49534.1 - 2.1 8.4 22.5 0.5 10.4 0.4 3.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DNA_ligase_A_M PF01068.16 EMG49535.1 - 0.065 12.5 0.1 0.078 12.3 0.1 1.0 1 0 0 1 1 1 0 ATP dependent DNA ligase domain GAD-like PF08887.6 EMG49536.1 - 0.078 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 GAD-like domain DUF566 PF04484.7 EMG49536.1 - 1.3 8.5 8.3 1.6 8.1 5.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Apt1 PF10351.4 EMG49536.1 - 1.8 7.3 6.0 2.4 6.9 4.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain PAP1 PF08601.5 EMG49536.1 - 2.1 7.9 18.8 2.5 7.6 13.1 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF605 PF04652.11 EMG49536.1 - 4.4 6.6 16.8 4.8 6.4 11.7 1.1 1 0 0 1 1 1 0 Vta1 like Secretin_N_2 PF07655.8 EMG49536.1 - 5 7.5 24.5 2 8.8 4.8 2.6 2 1 1 3 3 3 0 Secretin N-terminal domain Macoilin PF09726.4 EMG49536.1 - 6.5 4.9 9.9 7 4.7 6.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Menin PF05053.8 EMG49536.1 - 9.5 4.2 10.1 11 4.0 7.0 1.1 1 0 0 1 1 1 0 Menin Turandot PF07240.6 EMG49537.1 - 0.042 13.3 0.2 0.16 11.5 0.1 1.9 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot TFIIE_alpha PF02002.12 EMG49537.1 - 0.051 13.0 2.2 0.086 12.3 0.7 1.7 1 1 1 2 2 2 0 TFIIE alpha subunit DUF4296 PF14129.1 EMG49537.1 - 0.11 12.6 1.3 0.12 12.5 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4296) ABC_membrane_2 PF06472.10 EMG49538.1 - 1.1e-67 228.0 0.0 1.6e-67 227.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EMG49538.1 - 1.7e-19 70.5 0.0 4.4e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EMG49538.1 - 1.3e-05 25.3 0.1 6.6e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EMG49538.1 - 0.0012 18.3 0.0 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EMG49538.1 - 0.0014 18.9 5.9 0.0022 18.3 0.1 2.9 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EMG49538.1 - 0.009 16.0 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 EMG49538.1 - 0.019 14.1 0.2 0.047 12.9 0.2 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.12 EMG49538.1 - 0.028 13.8 0.0 0.066 12.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.8 EMG49538.1 - 0.043 12.7 0.0 0.1 11.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF815) DUF258 PF03193.11 EMG49538.1 - 0.092 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EMG49538.1 - 0.099 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EMG49538.1 - 0.1 12.0 0.2 0.48 9.7 0.1 2.0 2 0 0 2 2 2 0 AAA-like domain Mg_chelatase PF01078.16 EMG49538.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Peripla_BP_4 PF13407.1 EMG49539.1 - 0.00035 20.0 0.0 0.00065 19.1 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein domain Reo_sigmaC PF04582.7 EMG49539.1 - 0.32 10.1 21.2 0.42 9.7 1.8 2.7 2 1 0 3 3 3 0 Reovirus sigma C capsid protein TMF_TATA_bd PF12325.3 EMG49539.1 - 0.37 10.5 25.7 0.063 13.0 10.6 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding zf-C4H2 PF10146.4 EMG49539.1 - 0.48 10.4 27.4 0.14 12.1 9.6 2.6 1 1 1 2 2 2 0 Zinc finger-containing protein Shugoshin_N PF07558.6 EMG49539.1 - 0.75 9.5 12.6 0.59 9.8 0.3 3.8 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region IncA PF04156.9 EMG49539.1 - 1.3 8.5 28.7 58 3.1 19.9 2.6 1 1 0 1 1 1 0 IncA protein ADIP PF11559.3 EMG49539.1 - 2 8.3 32.8 0.41 10.5 13.1 3.4 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 EMG49539.1 - 2.6 7.5 20.3 0.2 11.1 2.6 4.0 2 1 1 3 3 3 0 Septum formation initiator SlyX PF04102.7 EMG49539.1 - 5.5 7.4 15.6 2.8 8.4 1.5 3.9 2 1 2 4 4 4 0 SlyX Syntaxin-6_N PF09177.6 EMG49539.1 - 6.6 7.2 24.9 0.17 12.2 2.0 3.9 3 1 1 4 4 4 0 Syntaxin 6, N-terminal Macoilin PF09726.4 EMG49539.1 - 6.8 4.8 32.9 48 2.0 22.8 2.0 1 1 0 1 1 1 0 Transmembrane protein DivIVA PF05103.8 EMG49539.1 - 7.6 6.5 29.0 6 6.9 8.8 3.8 1 1 2 3 3 3 0 DivIVA protein ApoO PF09769.4 EMG49539.1 - 8.1 6.1 6.9 2.9 7.5 1.9 2.3 1 1 2 3 3 3 0 Apolipoprotein O Lebercilin PF15619.1 EMG49539.1 - 9.4 5.6 32.6 6.7 6.0 6.2 2.6 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DAGK_cat PF00781.19 EMG49540.1 - 1.6e-25 89.0 0.0 2.5e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain LRR_4 PF12799.2 EMG49541.1 - 6e-30 102.3 72.1 2.8e-06 26.7 2.0 10.0 7 3 2 10 10 10 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG49541.1 - 3e-18 65.3 57.8 1.2e-05 24.9 2.9 9.0 3 2 5 10 10 10 8 Leucine rich repeat LRR_7 PF13504.1 EMG49541.1 - 1.9e-12 45.1 48.6 0.36 11.2 0.0 15.5 16 0 0 16 16 16 4 Leucine rich repeat LRR_1 PF00560.28 EMG49541.1 - 5.4e-12 43.9 52.9 0.62 10.3 0.0 14.8 12 4 3 15 15 15 7 Leucine Rich Repeat LRR_6 PF13516.1 EMG49541.1 - 1.6e-09 36.8 52.4 0.037 14.0 0.1 14.3 14 1 1 15 15 15 4 Leucine Rich repeat LRR_9 PF14580.1 EMG49541.1 - 0.02 14.4 8.6 0.7 9.4 0.5 3.9 1 1 2 3 3 3 0 Leucine-rich repeat LRR_2 PF07723.8 EMG49541.1 - 0.067 13.7 12.5 29 5.3 0.0 6.9 6 0 0 6 6 6 0 Leucine Rich Repeat FNIP PF05725.7 EMG49541.1 - 0.26 11.2 0.1 0.26 11.2 0.1 8.6 8 2 1 9 9 9 0 FNIP Repeat PC_rep PF01851.17 EMG49542.1 - 1.2e-40 135.4 21.7 1.3e-06 28.3 0.3 9.7 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EMG49542.1 - 4.2e-16 58.9 2.6 1.6e-10 41.1 0.0 4.5 4 0 0 4 4 4 3 HEAT repeats HEAT PF02985.17 EMG49542.1 - 1.5e-05 24.6 0.3 1.7 8.8 0.0 4.9 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EMG49542.1 - 6.3e-05 23.3 0.5 1.2 9.7 0.0 5.0 4 1 1 5 5 5 3 HEAT-like repeat TPR_8 PF13181.1 EMG49542.1 - 0.076 12.8 0.1 2.6 8.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat 2-Hacid_dh_C PF02826.14 EMG49543.1 - 5.2e-55 185.3 0.1 1.2e-54 184.1 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMG49543.1 - 3.3e-38 130.1 0.1 4.4e-38 129.7 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMG49543.1 - 3.9e-05 23.5 1.5 5.4e-05 23.0 0.1 1.9 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EMG49543.1 - 0.00018 21.3 0.2 0.00049 19.9 0.0 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.1 EMG49543.1 - 0.011 16.0 0.0 0.096 12.9 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain IlvN PF07991.7 EMG49543.1 - 0.013 14.8 0.2 0.042 13.2 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain ACT PF01842.20 EMG49543.1 - 0.014 14.8 0.0 0.047 13.1 0.0 1.9 1 0 0 1 1 1 0 ACT domain Acetyltransf_1 PF00583.19 EMG49543.1 - 0.017 15.1 0.0 0.067 13.2 0.0 2.1 2 1 0 2 2 2 0 Acetyltransferase (GNAT) family Mso1_Sec1_bdg PF14475.1 EMG49544.1 - 3.2e-20 71.2 0.1 8e-20 69.9 0.1 1.7 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Mso1_C PF14477.1 EMG49544.1 - 2e-08 34.4 3.5 2e-08 34.4 2.4 2.8 2 1 1 3 3 3 1 Membrane-polarising domain of Mso1 Y_phosphatase2 PF03162.8 EMG49545.1 - 5.4e-32 110.4 3.9 5.4e-32 110.4 2.7 2.8 2 2 0 2 2 2 1 Tyrosine phosphatase family CoA_binding_2 PF13380.1 EMG49546.1 - 5.8e-32 110.2 0.0 7.1e-32 110.0 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 EMG49546.1 - 0.0027 18.1 0.0 0.0043 17.5 0.0 1.4 1 1 0 1 1 1 1 CoA binding domain BBS1 PF14779.1 EMG49546.1 - 0.12 11.2 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 DUF1649 PF07855.7 EMG49547.1 - 7.3e-23 81.0 0.5 8.5e-23 80.8 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) Pkinase PF00069.20 EMG49548.1 - 1.8e-49 168.2 0.2 3.7e-49 167.2 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG49548.1 - 2.1e-21 76.2 0.0 3.6e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMG49548.1 - 0.023 14.4 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC1 PF03109.11 EMG49548.1 - 0.036 14.0 0.0 0.088 12.7 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Fungal_trans PF04082.13 EMG49549.1 - 0.00027 19.8 0.0 0.001 18.0 0.0 2.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG49549.1 - 0.00035 20.3 12.4 0.00064 19.5 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldolase_II PF00596.16 EMG49551.1 - 4.2e-48 163.3 0.2 5.1e-48 163.1 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Phage_Gp15 PF06854.6 EMG49551.1 - 0.019 14.5 0.1 0.03 13.8 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage Gp15 protein DUF619 PF04768.8 EMG49552.1 - 3.5e-50 169.7 1.3 9.2e-50 168.3 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EMG49552.1 - 8.4e-31 106.7 0.0 1.8e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EMG49552.1 - 1.6e-20 73.7 0.0 3.1e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 EMG49552.1 - 0.0075 16.1 0.0 0.022 14.6 0.0 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Herpes_UL92 PF03048.9 EMG49553.1 - 0.038 13.5 0.1 0.052 13.1 0.1 1.2 1 0 0 1 1 1 0 UL92 family RRP7 PF12923.2 EMG49555.1 - 0.22 11.5 2.4 0.21 11.6 0.4 2.0 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) DUF2962 PF11176.3 EMG49556.1 - 5.9e-53 178.5 7.7 6.7e-53 178.4 5.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) DUF2962 PF11176.3 EMG49558.1 - 5.9e-53 178.5 7.7 6.7e-53 178.4 5.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) RGS PF00615.14 EMG49560.1 - 1.2e-09 38.3 0.7 0.00031 20.8 0.2 2.5 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF1199 PF06712.6 EMG49560.1 - 0.81 9.5 5.2 0.21 11.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1199) Pyrophosphatase PF00719.14 EMG49561.1 - 0.056 12.8 0.4 3.9 6.8 0.1 2.6 2 0 0 2 2 2 0 Inorganic pyrophosphatase IPPT PF01715.12 EMG49563.1 - 7e-71 238.2 0.5 1.2e-70 237.4 0.2 1.4 2 0 0 2 2 2 1 IPP transferase AAA_17 PF13207.1 EMG49563.1 - 9e-06 26.5 0.1 3.2e-05 24.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMG49563.1 - 0.00018 21.8 0.8 0.0075 16.5 0.5 2.8 1 1 0 1 1 1 1 AAA domain IPT PF01745.11 EMG49563.1 - 0.00032 19.9 0.0 0.0009 18.4 0.0 1.7 2 0 0 2 2 2 1 Isopentenyl transferase AAA_33 PF13671.1 EMG49563.1 - 0.003 17.4 0.0 0.15 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain PPV_E1_C PF00519.12 EMG49563.1 - 0.028 13.0 0.5 0.19 10.2 0.0 2.1 2 0 0 2 2 2 0 Papillomavirus helicase DUF2309 PF10070.4 EMG49563.1 - 0.028 12.5 0.0 0.04 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) PRK PF00485.13 EMG49563.1 - 0.029 13.9 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 EMG49563.1 - 0.032 14.4 0.1 0.11 12.7 0.0 2.0 1 1 0 1 1 1 0 RNA helicase Arginase PF00491.16 EMG49563.1 - 0.063 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Arginase family BRO1 PF03097.13 EMG49564.1 - 1.4e-105 353.1 1.6 2.3e-105 352.4 1.1 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EMG49564.1 - 2e-63 214.1 10.3 3.2e-63 213.4 7.1 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF1380 PF07128.7 EMG49564.1 - 0.022 14.5 0.0 6.6 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1380) Myb_DNA-binding PF00249.26 EMG49565.1 - 1.1e-24 86.2 3.3 4.4e-12 45.8 0.1 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMG49565.1 - 2.2e-22 78.9 7.1 4.2e-14 52.3 0.9 3.4 3 1 1 4 4 4 2 Myb-like DNA-binding domain Rap1_C PF11626.3 EMG49565.1 - 0.0045 16.8 3.7 0.0065 16.3 0.0 3.0 3 0 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF718 PF05336.8 EMG49565.1 - 0.47 10.2 3.5 8.9 6.1 0.5 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF718) DASH_Hsk3 PF08227.6 EMG49565.1 - 7.9 6.7 7.0 12 6.1 0.0 3.4 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like LIP PF03583.9 EMG49566.1 - 4.6e-09 35.8 0.0 6.1e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase FNIP PF05725.7 EMG49567.1 - 0.2 11.6 17.5 1.3 9.0 0.0 6.5 6 1 1 7 7 7 0 FNIP Repeat F-box-like PF12937.2 EMG49567.1 - 0.92 9.2 4.0 1.2 8.9 0.6 2.4 2 0 0 2 2 2 0 F-box-like LIP PF03583.9 EMG49568.1 - 8.9e-110 366.4 0.0 1.1e-109 366.1 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 EMG49568.1 - 5.8e-06 26.1 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMG49568.1 - 0.002 18.0 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMG49568.1 - 0.05 12.8 0.0 0.53 9.4 0.1 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family FNIP PF05725.7 EMG49569.1 - 0.0012 18.7 16.6 0.0048 16.8 0.3 5.1 4 1 0 4 4 4 2 FNIP Repeat DUF3045 PF11243.3 EMG49569.1 - 0.083 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) LRR_8 PF13855.1 EMG49569.1 - 4.3 7.1 10.1 5.4 6.8 0.1 4.9 6 1 0 6 6 6 0 Leucine rich repeat Nup188 PF10487.4 EMG49570.1 - 0 1035.9 37.4 0 1035.4 25.9 1.2 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Pyrophosphatase PF00719.14 EMG49571.1 - 4.8e-39 133.3 0.2 6.8e-39 132.8 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF221 PF02714.10 EMG49572.1 - 2.2e-107 358.6 22.5 2.2e-107 358.6 15.6 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EMG49572.1 - 3e-38 130.8 0.3 3e-38 130.8 0.2 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EMG49572.1 - 1.1e-25 89.3 0.0 2.7e-25 88.0 0.0 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EMG49572.1 - 1.1e-14 54.6 1.8 1.1e-14 54.6 1.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) CAAD PF14159.1 EMG49572.1 - 2.8 7.6 8.9 0.13 11.8 0.5 3.2 3 1 1 4 4 4 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase PPTA PF01239.17 EMG49574.1 - 2.2e-39 131.1 12.9 7.6e-10 37.7 1.3 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat PSCyt2 PF07583.6 EMG49574.1 - 0.031 13.8 0.6 0.049 13.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1549) TPR_17 PF13431.1 EMG49574.1 - 0.12 12.6 0.3 7.8 6.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat N2227 PF07942.7 EMG49575.1 - 8.5e-47 159.3 0.0 1.3e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein WD40 PF00400.27 EMG49576.1 - 2e-33 113.0 10.2 1.9e-08 33.8 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.7 EMG49576.1 - 3e-24 84.8 0.2 5.1e-24 84.0 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 EMG49576.1 - 4e-06 25.2 3.7 0.021 12.9 0.1 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 FAM117 PF15388.1 EMG49576.1 - 0.062 12.5 0.0 0.45 9.6 0.0 2.2 1 1 0 1 1 1 0 Protein Family FAM117 GATase PF00117.23 EMG49577.1 - 4.3e-41 140.4 0.0 7.6e-41 139.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 EMG49577.1 - 8.9e-40 134.3 0.1 3e-39 132.6 0.1 1.9 2 0 0 2 2 2 1 GMP synthase C terminal domain NAD_synthase PF02540.12 EMG49577.1 - 1.2e-09 37.4 0.1 2e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EMG49577.1 - 5.3e-08 32.5 0.1 3.4e-07 29.9 0.0 2.3 1 1 0 1 1 1 1 Peptidase C26 QueC PF06508.8 EMG49577.1 - 0.0019 17.5 0.0 0.077 12.2 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EMG49577.1 - 0.022 13.3 0.1 0.044 12.3 0.1 1.5 1 0 0 1 1 1 0 tRNA methyl transferase Asn_synthase PF00733.16 EMG49577.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase ACPS PF01648.15 EMG49578.1 - 3.6e-16 58.9 0.1 4.2e-16 58.7 0.0 1.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Mtc PF03820.12 EMG49579.1 - 1.6e-117 391.5 0.1 1.8e-117 391.3 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Polysacc_synt_C PF14667.1 EMG49579.1 - 0.37 10.5 7.0 0.033 13.9 1.6 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain GHMP_kinases_N PF00288.21 EMG49580.1 - 5.9e-22 77.5 0.9 2.6e-21 75.4 0.1 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EMG49580.1 - 1.2e-08 35.0 0.0 2.7e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 EMG49580.1 - 0.0011 18.1 0.0 0.0033 16.6 0.0 1.8 1 0 0 1 1 1 1 Galactokinase galactose-binding signature LRR_4 PF12799.2 EMG49581.1 - 0.045 13.3 3.4 35 4.1 0.0 5.0 6 1 0 6 6 6 0 Leucine Rich repeats (2 copies) FNIP PF05725.7 EMG49581.1 - 0.13 12.2 7.8 7.7 6.5 0.0 4.7 4 1 2 6 6 5 0 FNIP Repeat LRR_7 PF13504.1 EMG49581.1 - 6.1 7.5 6.1 59 4.5 0.0 5.1 6 1 0 6 6 6 0 Leucine rich repeat LIP PF03583.9 EMG49582.1 - 2.2e-106 355.3 0.0 3.1e-106 354.8 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 EMG49582.1 - 7.2e-06 25.8 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family FNIP PF05725.7 EMG49582.1 - 0.68 9.9 11.9 30 4.6 0.1 5.3 5 2 0 5 5 5 0 FNIP Repeat FNIP PF05725.7 EMG49583.1 - 6.2e-06 26.0 9.3 0.075 12.9 0.0 5.5 4 1 0 4 4 4 3 FNIP Repeat BSP_II PF05432.6 EMG49583.1 - 0.28 10.4 8.5 0.4 9.9 5.9 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CDC45 PF02724.9 EMG49583.1 - 2.9 5.7 12.2 4.2 5.2 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_28 PF02636.12 EMG49584.1 - 3.5e-37 128.1 0.0 5.8e-37 127.4 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Iso_dh PF00180.15 EMG49586.1 - 5.9e-82 275.4 0.1 7.5e-82 275.0 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Rep_fac-A_3 PF08661.6 EMG49587.1 - 1.1e-25 89.5 0.1 1.3e-25 89.4 0.1 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Ten1_2 PF15490.1 EMG49587.1 - 0.0048 16.4 0.0 0.0058 16.2 0.0 1.2 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit DUF2518 PF10726.4 EMG49587.1 - 0.039 13.4 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of function (DUF2518) PUL PF08324.6 EMG49588.1 - 4.2e-52 176.5 3.2 6.2e-52 176.0 2.2 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 EMG49588.1 - 3e-45 152.9 0.1 5.3e-45 152.1 0.1 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 EMG49588.1 - 3.3e-45 150.3 12.1 2.6e-08 33.4 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat BBS2_Mid PF14783.1 EMG49588.1 - 0.0023 17.6 0.0 0.13 12.0 0.0 3.3 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Adenylsucc_synt PF00709.16 EMG49589.1 - 2e-168 560.4 0.0 2.2e-168 560.2 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase MCD PF05292.6 EMG49589.1 - 0.098 11.3 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase (MCD) CMAS PF02353.15 EMG49590.1 - 1.4e-64 217.8 0.3 1.7e-64 217.5 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EMG49590.1 - 2.2e-16 60.0 0.0 3.7e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMG49590.1 - 1.6e-07 31.6 0.0 2.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMG49590.1 - 5.9e-06 26.8 0.0 1.2e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMG49590.1 - 3.2e-05 23.5 0.0 5.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMG49590.1 - 0.00012 22.0 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EMG49590.1 - 0.00027 20.9 0.2 0.0007 19.6 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.7 EMG49590.1 - 0.00049 20.5 0.0 0.00098 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMG49590.1 - 0.00097 19.4 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EMG49590.1 - 0.0016 17.7 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.9 EMG49590.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 EMG49590.1 - 0.022 14.2 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) BING4CT PF08149.6 EMG49591.1 - 4.7e-40 134.9 0.0 4.8e-37 125.3 0.0 3.0 2 0 0 2 2 2 2 BING4CT (NUC141) domain WD40 PF00400.27 EMG49591.1 - 6.5e-06 25.8 0.0 0.00014 21.5 0.0 3.1 4 0 0 4 4 4 1 WD domain, G-beta repeat Mid2 PF04478.7 EMG49591.1 - 0.048 13.0 0.1 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Malate_synthase PF01274.17 EMG49592.1 - 5.6e-225 747.2 0.0 6.3e-225 747.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.9 EMG49592.1 - 0.01 14.7 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Mito_carr PF00153.22 EMG49593.1 - 4e-47 157.8 7.7 1.5e-19 69.4 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-CCHC PF00098.18 EMG49594.1 - 2.3e-05 24.1 38.8 0.016 15.1 1.3 5.5 5 1 0 5 5 5 3 Zinc knuckle zf-CCHC_3 PF13917.1 EMG49594.1 - 1 9.1 29.5 0.041 13.6 1.6 5.2 2 1 3 5 5 5 0 Zinc knuckle DUF35_N PF12172.3 EMG49594.1 - 1.9 8.5 0.0 1.9 8.5 0.0 3.6 4 0 0 4 4 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) FAD_binding_8 PF08022.7 EMG49596.1 - 0.055 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 FAD-binding domain SURF1 PF02104.10 EMG49597.1 - 2.6e-56 190.7 0.0 3.4e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 SURF1 family GET2 PF08690.5 EMG49598.1 - 1e-98 330.3 0.0 1.1e-98 330.1 0.0 1.0 1 0 0 1 1 1 1 GET complex subunit GET2 DASH_Dam1 PF08653.5 EMG49599.1 - 1.6e-25 88.5 1.4 3e-25 87.7 0.2 1.9 2 0 0 2 2 2 1 DASH complex subunit Dam1 Herpes_U30 PF04523.8 EMG49599.1 - 0.014 12.8 0.1 0.018 12.4 0.0 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 DUF2265 PF10023.4 EMG49599.1 - 0.016 14.3 0.1 0.022 13.9 0.0 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) Syntaxin PF00804.20 EMG49599.1 - 0.036 14.2 0.2 0.16 12.1 0.1 2.1 1 1 0 1 1 1 0 Syntaxin DivIVA PF05103.8 EMG49599.1 - 0.11 12.5 0.8 0.39 10.7 0.3 2.0 2 0 0 2 2 2 0 DivIVA protein Mcm10 PF09332.6 EMG49599.1 - 0.13 11.6 3.9 0.2 10.9 2.7 1.3 1 0 0 1 1 1 0 Mcm10 replication factor V_ATPase_I PF01496.14 EMG49599.1 - 0.23 9.2 2.6 0.43 8.3 0.9 1.6 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 EMG49599.1 - 1.4 7.8 6.2 1.1 8.1 3.4 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CDC37_N PF03234.9 EMG49599.1 - 1.9 8.8 5.1 4.4 7.5 2.7 2.1 2 1 0 2 2 2 0 Cdc37 N terminal kinase binding DHO_dh PF01180.16 EMG49600.1 - 3.4e-99 331.5 0.0 4.2e-99 331.2 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 EMG49600.1 - 0.015 14.1 0.0 0.68 8.7 0.0 2.4 2 1 0 2 2 2 0 FMN-dependent dehydrogenase PcrB PF01884.12 EMG49600.1 - 0.12 11.5 0.3 14 4.8 0.1 2.6 3 0 0 3 3 3 0 PcrB family NAD_binding_10 PF13460.1 EMG49604.1 - 3.1e-09 37.1 0.0 3.9e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding HIM1 PF08732.5 EMG49604.1 - 1.1e-07 30.7 0.0 1.9e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 HIM1 Epimerase PF01370.16 EMG49604.1 - 0.00023 20.6 0.0 0.00039 19.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMG49604.1 - 0.0033 16.3 0.0 0.63 8.9 0.0 2.5 1 1 1 3 3 3 2 Male sterility protein NmrA PF05368.8 EMG49604.1 - 0.011 15.0 0.3 0.046 12.9 0.2 1.9 1 1 0 1 1 1 0 NmrA-like family DapB_N PF01113.15 EMG49604.1 - 0.013 15.4 0.0 0.14 12.1 0.0 2.4 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EMG49604.1 - 0.023 14.9 0.3 0.093 13.0 0.0 2.2 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF1399 PF07173.7 EMG49605.1 - 1.8e-38 131.8 2.3 2.5e-36 124.9 0.1 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1399) TPR_11 PF13414.1 EMG49606.1 - 1.8e-39 133.2 35.9 5.1e-09 35.6 0.4 12.1 9 4 3 13 13 13 8 TPR repeat TPR_19 PF14559.1 EMG49606.1 - 5.1e-31 106.8 20.7 2.8e-09 37.1 0.0 10.8 10 2 2 12 12 10 7 Tetratricopeptide repeat TPR_14 PF13428.1 EMG49606.1 - 9.2e-31 103.5 10.9 0.0023 18.4 0.0 12.0 8 4 4 12 12 10 9 Tetratricopeptide repeat TPR_16 PF13432.1 EMG49606.1 - 3.9e-30 103.8 9.2 9.8e-06 26.1 0.0 9.9 8 2 2 10 10 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 EMG49606.1 - 5.4e-29 97.7 32.0 5.1e-05 22.8 0.3 15.0 15 0 0 15 15 13 6 Tetratricopeptide repeat TPR_1 PF00515.23 EMG49606.1 - 4.2e-26 89.4 38.4 9.9e-05 21.7 0.3 14.8 16 0 0 16 16 15 6 Tetratricopeptide repeat TPR_12 PF13424.1 EMG49606.1 - 4.8e-24 84.0 24.7 1.6e-05 24.7 0.0 10.3 7 3 2 10 10 9 5 Tetratricopeptide repeat TPR_17 PF13431.1 EMG49606.1 - 9.3e-19 66.0 17.2 0.0026 17.8 0.2 11.2 12 0 0 12 12 11 4 Tetratricopeptide repeat Apc3 PF12895.2 EMG49606.1 - 1.2e-16 60.6 12.6 1.1e-05 25.4 0.5 7.5 6 1 1 7 7 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EMG49606.1 - 1.7e-14 53.1 15.3 0.095 13.2 0.0 12.8 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_7 PF13176.1 EMG49606.1 - 1.4e-13 49.5 10.6 0.039 13.7 0.1 9.5 10 0 0 10 10 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 EMG49606.1 - 1.6e-13 49.3 34.5 0.00089 18.8 0.0 13.0 16 0 0 16 16 12 3 Tetratricopeptide repeat TPR_9 PF13371.1 EMG49606.1 - 2.3e-13 49.8 0.5 0.0016 18.2 0.0 6.0 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 EMG49606.1 - 2.2e-07 30.5 8.1 0.81 9.7 0.2 7.0 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_4 PF07721.9 EMG49606.1 - 6.9e-05 22.8 0.0 16 6.2 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMG49606.1 - 7.1e-05 22.6 11.5 0.96 9.3 0.0 7.1 7 0 0 7 7 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.1 EMG49606.1 - 0.00026 20.1 14.1 0.078 12.0 0.0 5.4 4 2 1 6 6 6 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 EMG49606.1 - 0.0015 17.6 3.8 4.7 6.5 0.0 5.1 5 0 0 5 5 5 1 SHNi-TPR TPR_20 PF14561.1 EMG49606.1 - 0.016 15.2 9.9 7.7 6.7 0.0 6.2 8 0 0 8 8 5 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 EMG49606.1 - 0.057 12.8 9.1 0.43 10.0 1.6 3.7 3 1 1 4 4 4 0 Foie gras liver health family 1 Sel1 PF08238.7 EMG49606.1 - 0.31 11.7 4.5 39 5.0 0.0 4.9 5 0 0 5 5 3 0 Sel1 repeat MMR_HSR1_C PF08438.5 EMG49607.1 - 3e-32 111.0 0.0 4.8e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EMG49607.1 - 4.9e-16 58.7 0.0 9.4e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMG49607.1 - 4.4e-08 32.5 0.1 9.8e-06 24.9 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 EMG49607.1 - 0.0015 18.0 0.0 0.64 9.4 0.0 2.5 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 EMG49607.1 - 0.0052 15.5 0.4 0.017 13.9 0.1 1.9 2 0 0 2 2 2 1 ArgK protein AAA_10 PF12846.2 EMG49607.1 - 0.037 13.4 0.0 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain Dynamin_N PF00350.18 EMG49607.1 - 0.045 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Dynamin family ATP_bind_1 PF03029.12 EMG49607.1 - 0.047 13.2 0.1 6.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Cg6151-P PF10233.4 EMG49608.1 - 2.2e-38 130.7 15.8 2.6e-38 130.4 11.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Na_Ala_symp PF01235.12 EMG49608.1 - 0.6 8.6 7.4 0.034 12.7 1.8 1.4 2 0 0 2 2 2 0 Sodium:alanine symporter family MFS_2 PF13347.1 EMG49608.1 - 1.5 7.1 11.9 0.099 11.0 3.6 1.9 2 0 0 2 2 2 0 MFS/sugar transport protein Glyco_trans_1_3 PF13528.1 EMG49609.1 - 0.038 13.1 0.1 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF4367 PF14285.1 EMG49609.1 - 0.63 9.3 9.0 0.086 12.1 3.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4367) Ribosomal_L44 PF00935.14 EMG49610.1 - 1.6e-33 114.5 14.6 2.6e-33 113.8 10.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Mannosyl_trans3 PF11051.3 EMG49611.1 - 4.4e-84 282.0 0.0 7.5e-84 281.2 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative NTF2 PF02136.15 EMG49613.1 - 3e-32 111.4 0.1 5.4e-32 110.6 0.1 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain TFIIE_beta PF02186.10 EMG49613.1 - 2.7e-26 91.3 0.6 7.2e-26 89.9 0.4 1.8 1 0 0 1 1 1 1 TFIIE beta subunit core domain F-box-like PF12937.2 EMG49614.1 - 0.0011 18.6 0.0 0.0029 17.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like Gti1_Pac2 PF09729.4 EMG49615.1 - 7e-53 178.9 0.2 7e-53 178.9 0.1 2.6 2 1 0 2 2 2 1 Gti1/Pac2 family ERO1 PF04137.10 EMG49616.1 - 8.9e-115 383.5 3.6 1.4e-114 382.9 2.5 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DEAD PF00270.24 EMG49618.1 - 3.1e-48 163.4 0.1 8.3e-47 158.8 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG49618.1 - 1.4e-27 95.3 0.0 9.5e-27 92.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMG49618.1 - 5.1e-06 26.4 0.0 5.1e-06 26.4 0.0 2.7 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EMG49618.1 - 6.1e-05 21.6 0.8 6.1e-05 21.6 0.5 3.4 3 1 0 3 3 3 2 Protein of unknown function (DUF1253) CMS1 PF14617.1 EMG49618.1 - 0.00031 19.8 14.0 0.0072 15.4 0.0 2.8 2 0 0 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit Tim54 PF11711.3 EMG49618.1 - 7.5 5.0 12.9 3.6 6.0 7.4 1.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 GATA PF00320.22 EMG49619.1 - 6.5e-31 105.3 22.4 2e-16 59.0 4.3 3.1 3 0 0 3 3 3 2 GATA zinc finger ArfGap PF01412.13 EMG49619.1 - 0.00032 20.4 7.4 0.06 13.1 0.1 2.9 3 0 0 3 3 3 2 Putative GTPase activating protein for Arf TF_Zn_Ribbon PF08271.7 EMG49619.1 - 0.0047 16.2 0.3 0.0047 16.2 0.2 2.9 3 0 0 3 3 3 2 TFIIB zinc-binding RRN7 PF11781.3 EMG49619.1 - 0.0067 15.8 14.1 0.046 13.2 0.3 2.9 3 0 0 3 3 3 2 RNA polymerase I-specific transcription initiation factor Rrn7 OrfB_Zn_ribbon PF07282.6 EMG49619.1 - 0.023 14.3 0.4 0.023 14.3 0.3 2.9 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 EMG49619.1 - 0.63 10.0 9.6 4.1 7.4 0.1 3.5 3 0 0 3 3 3 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.12 EMG49619.1 - 0.84 9.3 3.7 11 5.6 0.3 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-C2H2_3 PF13878.1 EMG49619.1 - 0.91 9.1 7.1 9.6 5.8 0.0 4.1 4 0 0 4 4 4 0 zinc-finger of acetyl-transferase ESCO Auto_anti-p27 PF06677.7 EMG49619.1 - 5.8 6.7 11.9 0.83 9.4 0.4 3.0 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Pkinase PF00069.20 EMG49620.1 - 1.3e-40 139.1 0.8 5.1e-40 137.2 0.0 2.4 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG49620.1 - 6.4e-25 87.6 0.0 2e-24 86.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase DSPc PF00782.15 EMG49622.1 - 5.4e-30 103.6 0.2 5.4e-30 103.6 0.1 2.4 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMG49622.1 - 4.6e-05 22.8 0.8 9.4e-05 21.8 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Syja_N PF02383.13 EMG49623.1 - 9e-71 238.2 4.8 1.1e-70 238.0 3.3 1.1 1 0 0 1 1 1 1 SacI homology domain Cut8_C PF08559.5 EMG49624.1 - 4.9e-48 162.5 3.2 8e-48 161.9 2.2 1.3 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 EMG49624.1 - 1.1e-13 50.7 3.2 1.1e-13 50.7 2.2 1.7 2 0 0 2 2 2 1 Cut8 dimerisation domain Cut8_N PF14482.1 EMG49624.1 - 0.0061 16.5 8.8 0.0061 16.5 6.1 2.4 1 1 1 2 2 2 1 Cut8 proteasome-binding domain VPS28 PF03997.7 EMG49624.1 - 0.022 14.3 1.2 0.62 9.6 0.1 2.4 2 0 0 2 2 2 0 VPS28 protein Abhydrolase_6 PF12697.2 EMG49625.1 - 2.8e-15 56.8 0.0 3.2e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMG49625.1 - 1.1e-14 54.0 0.0 2.1e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 EMG49625.1 - 6.9e-14 51.8 0.0 7.7e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMG49625.1 - 1.5e-11 44.2 0.0 1.9e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2305 PF10230.4 EMG49625.1 - 0.027 13.9 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 EMG49625.1 - 0.053 13.1 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF915 PF06028.6 EMG49625.1 - 0.17 10.9 0.6 0.37 9.8 0.1 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) 2-Hacid_dh PF00389.25 EMG49626.1 - 9.2e-15 54.2 0.0 1.1e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DUF2325 PF10087.4 EMG49626.1 - 0.044 13.6 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) DUF2408 PF10303.4 EMG49627.1 - 4.4e-51 172.4 28.5 1.6e-35 122.1 7.1 5.2 4 1 1 5 5 5 4 Protein of unknown function (DUF2408) DUF3391 PF11871.3 EMG49627.1 - 0.054 13.7 0.3 0.49 10.6 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3391) 2-Hacid_dh_C PF02826.14 EMG49628.1 - 2.5e-36 124.4 0.0 7.2e-36 122.9 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EMG49628.1 - 0.00042 20.2 0.0 0.00072 19.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EMG49628.1 - 0.011 15.8 0.0 0.12 12.5 0.0 2.1 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EMG49628.1 - 0.053 13.3 0.1 2.5 7.9 0.0 2.3 1 1 1 2 2 2 0 ThiF family TFIIE_alpha PF02002.12 EMG49629.1 - 1.9e-22 78.7 2.3 1.1e-21 76.2 0.1 2.4 2 0 0 2 2 2 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 EMG49629.1 - 0.00017 20.8 2.3 0.001 18.3 1.5 2.2 1 1 0 1 1 1 1 TFIIB zinc-binding NodS PF05401.6 EMG49629.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Zn_Tnp_IS1595 PF12760.2 EMG49629.1 - 0.14 12.0 0.1 0.32 10.8 0.1 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain RRN7 PF11781.3 EMG49629.1 - 0.36 10.3 2.4 3.3 7.2 0.6 2.4 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Selenoprotein_S PF06936.6 EMG49629.1 - 3.1 7.2 10.8 2.3 7.7 3.1 2.4 1 1 0 2 2 2 0 Selenoprotein S (SelS) Fork_head PF00250.13 EMG49630.1 - 7.3e-33 112.4 0.2 2.2e-32 110.9 0.1 1.8 1 0 0 1 1 1 1 Fork head domain PBP1_TM PF14812.1 EMG49630.1 - 0.4 11.0 8.0 0.18 12.1 0.3 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Complex1_LYR_2 PF13233.1 EMG49631.1 - 9e-18 64.6 1.1 1.1e-17 64.4 0.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Med11 PF10280.4 EMG49631.1 - 0.019 15.0 0.6 0.028 14.4 0.4 1.3 1 1 0 1 1 1 0 Mediator complex protein DDE_1 PF03184.14 EMG49632.1 - 7.6e-38 129.8 0.5 3.6e-37 127.6 0.4 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EMG49632.1 - 1.6e-13 50.2 0.2 4e-13 48.9 0.2 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain PEP-utilisers_N PF05524.8 EMG49633.1 - 0.028 14.2 0.1 0.033 13.9 0.1 1.1 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal GvpL_GvpF PF06386.6 EMG49633.1 - 0.081 12.4 0.2 0.091 12.3 0.1 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF HTH_31 PF13560.1 EMG49633.1 - 0.081 13.1 0.3 0.15 12.2 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain FeoA PF04023.9 EMG49633.1 - 0.087 12.8 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 FeoA domain HTH_25 PF13413.1 EMG49633.1 - 0.34 10.5 2.9 0.4 10.3 1.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Cwf_Cwc_15 PF04889.7 EMG49633.1 - 0.35 10.5 4.6 0.44 10.2 3.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF846 PF05832.7 EMG49634.1 - 1e-53 180.8 10.7 1.3e-53 180.5 7.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Pex14_N PF04695.8 EMG49634.1 - 0.12 12.4 1.0 0.19 11.8 0.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2360 PF10152.4 EMG49634.1 - 1.1 9.4 3.8 1.7 8.9 2.6 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) MFS_1 PF07690.11 EMG49634.1 - 3.7 6.1 15.7 7.8 5.0 10.6 1.6 1 1 1 2 2 2 0 Major Facilitator Superfamily Clathrin PF00637.15 EMG49636.1 - 1.2e-27 96.2 9.2 3.6e-27 94.7 1.7 3.2 3 1 0 3 3 3 2 Region in Clathrin and VPS WD40 PF00400.27 EMG49636.1 - 0.003 17.3 0.5 0.03 14.2 0.0 2.9 4 0 0 4 4 4 1 WD domain, G-beta repeat Vps39_1 PF10366.4 EMG49636.1 - 0.022 14.7 7.8 0.024 14.6 0.5 3.0 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 APG5 PF04106.7 EMG49636.1 - 0.081 12.3 2.5 0.08 12.4 0.3 2.0 2 1 1 3 3 3 0 Autophagy protein Apg5 Sporozoite_P67 PF05642.6 EMG49636.1 - 8.5 4.0 6.9 15 3.2 4.8 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NAD_binding_10 PF13460.1 EMG49637.1 - 6.7e-16 58.8 0.1 8.8e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding HIM1 PF08732.5 EMG49637.1 - 1.6e-06 26.8 0.2 5.2e-06 25.1 0.0 1.7 1 1 1 2 2 2 1 HIM1 Semialdhyde_dh PF01118.19 EMG49637.1 - 0.0015 18.8 0.3 0.22 11.8 0.0 2.7 2 1 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EMG49637.1 - 0.0034 16.8 0.0 0.0063 15.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EMG49637.1 - 0.0048 15.8 0.0 0.9 8.3 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain NmrA PF05368.8 EMG49637.1 - 0.0079 15.4 0.2 0.021 14.0 0.1 1.9 1 1 0 1 1 1 1 NmrA-like family DapB_N PF01113.15 EMG49637.1 - 0.0093 15.8 0.0 0.085 12.7 0.0 2.3 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus DsrH PF04077.7 EMG49637.1 - 0.088 12.4 0.1 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 DsrH like protein DNA_pol3_theta PF06440.6 EMG49637.1 - 0.094 12.3 1.0 1.4 8.5 0.1 2.2 2 0 0 2 2 2 0 DNA polymerase III, theta subunit MAGE PF01454.14 EMG49637.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 MAGE family LRR_1 PF00560.28 EMG49638.1 - 2.8e-08 32.6 27.3 0.51 10.5 0.1 11.0 6 3 2 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.1 EMG49638.1 - 2.9e-08 33.3 25.9 0.00041 20.0 0.9 8.1 7 3 4 11 11 11 3 Leucine rich repeat LRR_7 PF13504.1 EMG49638.1 - 1.4e-05 24.5 17.8 13 6.4 0.0 10.6 10 1 0 10 10 10 2 Leucine rich repeat LRR_9 PF14580.1 EMG49638.1 - 0.0025 17.3 0.8 0.012 15.2 0.1 2.4 2 1 1 3 3 3 1 Leucine-rich repeat LRR_4 PF12799.2 EMG49638.1 - 0.0054 16.3 2.9 0.0054 16.3 2.0 11.5 9 5 3 12 12 12 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EMG49638.1 - 0.039 14.0 24.7 6.7 7.1 0.1 9.8 9 1 2 11 11 11 0 Leucine Rich repeat SRP-alpha_N PF04086.8 EMG49639.1 - 0.034 13.5 0.1 0.053 12.9 0.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Arrestin_C PF02752.17 EMG49640.1 - 3.3e-30 104.9 3.7 2.2e-29 102.2 0.0 3.7 3 2 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain dsDNA_bind PF01984.15 EMG49640.1 - 0.33 10.9 0.0 0.33 10.9 0.0 3.1 3 0 0 3 3 3 0 Double-stranded DNA-binding domain DUF3715 PF12509.3 EMG49641.1 - 0.04 13.7 0.0 0.041 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3715) Pkinase PF00069.20 EMG49642.1 - 1.8e-69 233.7 0.6 2.9e-69 233.1 0.4 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG49642.1 - 8e-52 175.8 0.2 1.2e-51 175.3 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EMG49642.1 - 1.6e-20 73.2 0.3 1.6e-20 73.2 0.2 3.2 3 0 0 3 3 3 1 P21-Rho-binding domain Kinase-like PF14531.1 EMG49642.1 - 1.8e-08 33.6 1.1 2.2e-08 33.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like PH PF00169.24 EMG49642.1 - 8.2e-05 22.7 0.5 0.0003 20.9 0.3 2.0 1 0 0 1 1 1 1 PH domain Seadorna_VP7 PF07387.6 EMG49642.1 - 0.0014 17.5 0.1 0.0027 16.6 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EMG49642.1 - 0.019 14.6 0.1 0.049 13.3 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.11 EMG49643.1 - 4.7e-31 107.7 13.4 4.7e-31 107.7 9.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily FoP_duplication PF13865.1 EMG49644.1 - 3.8e-15 56.0 5.5 3.8e-15 56.0 3.8 2.4 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Ivy PF08816.6 EMG49644.1 - 0.002 18.0 0.1 0.0046 16.9 0.0 1.5 2 0 0 2 2 2 1 Inhibitor of vertebrate lysozyme (Ivy) RRM_3 PF08777.6 EMG49644.1 - 0.0054 16.5 0.4 0.044 13.6 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif RRM_6 PF14259.1 EMG49644.1 - 0.012 15.6 0.1 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMG49644.1 - 0.012 15.2 0.1 0.025 14.2 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 EMG49645.1 - 3.6e-69 232.7 0.0 5.6e-69 232.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG49645.1 - 5.6e-39 133.7 0.0 7.6e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG49645.1 - 9.8e-06 24.7 0.0 1.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EMG49645.1 - 0.039 13.3 0.2 0.34 10.2 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL PH_5 PF15405.1 EMG49645.1 - 0.047 13.6 1.2 0.074 13.0 0.8 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Pkinase PF00069.20 EMG49646.1 - 9.6e-32 110.1 1.6 2.1e-31 109.0 1.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG49646.1 - 2e-14 53.3 0.0 3.9e-14 52.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase RNA_polI_A34 PF08208.6 EMG49647.1 - 2.4e-48 164.4 18.1 3.3e-48 164.0 12.6 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 TRAP_alpha PF03896.11 EMG49647.1 - 0.41 9.5 11.3 0.36 9.7 0.1 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit SspB PF04386.8 EMG49647.1 - 0.9 9.1 5.6 1.7 8.2 3.9 1.5 1 0 0 1 1 1 0 Stringent starvation protein B Methyltransf_6 PF03737.10 EMG49648.1 - 1.8e-23 83.0 0.1 4.2e-23 81.8 0.0 1.6 2 0 0 2 2 2 1 Demethylmenaquinone methyltransferase DUF3715 PF12509.3 EMG49650.1 - 0.037 13.8 0.0 0.04 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3715) Glyco_hydro_31 PF01055.21 EMG49651.1 - 6.4e-156 519.6 4.4 8.1e-156 519.2 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Mannosyl_trans3 PF11051.3 EMG49652.1 - 1.6e-71 240.8 0.7 1.6e-71 240.8 0.5 1.9 2 0 0 2 2 2 1 Mannosyltransferase putative OKR_DC_1_N PF03709.10 EMG49652.1 - 0.052 13.6 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain AAA_14 PF13173.1 EMG49652.1 - 1.9 8.4 6.9 0.52 10.2 1.8 2.3 2 1 0 2 2 2 0 AAA domain Bul1_C PF04426.7 EMG49655.1 - 2.5e-12 46.5 2.4 4.6e-06 26.0 0.0 2.3 1 1 1 2 2 2 2 Bul1 C terminus DUF4519 PF15012.1 EMG49658.1 - 0.0057 16.5 0.1 3 7.8 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4519) DUF2759 PF10958.3 EMG49658.1 - 0.018 14.5 0.6 0.018 14.5 0.4 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF2759) DUF2306 PF10067.4 EMG49658.1 - 3.8 7.6 9.1 9.4 6.4 2.3 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2306) DUF2838 PF10998.3 EMG49659.1 - 2.6e-37 127.0 12.9 2.6e-37 127.0 8.9 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) HALZ PF02183.13 EMG49659.1 - 0.0059 16.3 2.9 0.018 14.7 2.0 1.8 1 0 0 1 1 1 1 Homeobox associated leucine zipper DivIC PF04977.10 EMG49659.1 - 0.047 13.1 1.0 0.15 11.5 0.1 2.4 2 0 0 2 2 2 0 Septum formation initiator FUN14 PF04930.10 EMG49659.1 - 0.15 12.3 0.2 11 6.3 0.0 2.4 2 0 0 2 2 2 0 FUN14 family DnaJ-X PF14308.1 EMG49660.1 - 8.3e-64 214.6 29.5 1.1e-36 126.0 7.5 3.1 2 2 1 3 3 3 2 X-domain of DnaJ-containing DnaJ PF00226.26 EMG49660.1 - 1.1e-18 66.6 2.9 1.1e-18 66.6 2.0 2.5 2 0 0 2 2 2 1 DnaJ domain Ribosomal_S5 PF00333.15 EMG49660.1 - 8.6e-16 57.4 0.1 7e-15 54.5 0.1 2.4 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EMG49660.1 - 3e-10 39.2 0.0 4.8e-09 35.3 0.0 2.6 3 0 0 3 3 3 1 Ribosomal protein S5, C-terminal domain Peptidase_M1 PF01433.15 EMG49661.1 - 4.5e-62 210.3 0.0 8.6e-62 209.4 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EMG49661.1 - 6.4e-43 145.7 0.0 1.3e-42 144.7 0.0 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EMG49661.1 - 2.6e-13 50.1 0.1 4.6e-13 49.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EMG49661.1 - 0.34 10.8 2.0 2 8.4 1.4 2.2 1 1 0 1 1 1 0 M61 glycyl aminopeptidase DOPA_dioxygen PF08883.6 EMG49662.1 - 4.7e-31 106.9 0.0 5.7e-31 106.6 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family BAG PF02179.11 EMG49663.1 - 1.2e-23 83.0 2.0 2.8e-23 81.8 1.4 1.6 1 0 0 1 1 1 1 BAG domain DUF2935 PF11155.3 EMG49663.1 - 0.2 11.7 2.5 0.37 10.9 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) DUF1690 PF07956.6 EMG49663.1 - 0.21 11.5 3.4 0.45 10.4 2.3 1.6 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) ING PF12998.2 EMG49663.1 - 1.2 9.4 6.9 0.86 9.9 0.6 3.0 1 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF4473 PF14747.1 EMG49663.1 - 2.9 8.1 5.9 3 8.1 0.1 3.0 2 2 2 4 4 4 0 Domain of unknown function (DUF4473) PIG-L PF02585.12 EMG49664.1 - 3e-27 95.6 0.0 3.7e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase MFS_1 PF07690.11 EMG49666.1 - 3e-11 42.6 18.4 3e-11 42.6 12.7 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Alk_phosphatase PF00245.15 EMG49667.1 - 2.3e-82 276.9 0.0 3.1e-82 276.5 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.18 EMG49667.1 - 0.023 13.8 0.9 4.1 6.4 0.6 3.1 1 1 1 2 2 2 0 Sulfatase Phosphodiest PF01663.17 EMG49667.1 - 0.041 13.1 2.2 0.077 12.3 0.4 2.0 1 1 0 3 3 3 0 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EMG49667.1 - 0.058 12.7 0.1 0.17 11.2 0.2 1.6 2 0 0 2 2 2 0 Metalloenzyme superfamily fn3 PF00041.16 EMG49668.1 - 0.00044 20.3 0.0 0.0025 17.9 0.0 2.4 1 1 0 1 1 1 1 Fibronectin type III domain Filament PF00038.16 EMG49668.1 - 0.062 12.7 29.0 0.6 9.5 13.0 2.7 1 1 1 2 2 2 0 Intermediate filament protein Uds1 PF15456.1 EMG49668.1 - 0.34 10.9 15.5 0.062 13.3 7.1 2.2 1 1 1 2 2 2 0 Up-regulated During Septation PEARLI-4 PF05278.7 EMG49668.1 - 6.1 6.1 25.7 0.13 11.5 5.2 2.9 2 1 1 3 3 3 0 Arabidopsis phospholipase-like protein (PEARLI 4) Beta_elim_lyase PF01212.16 EMG49669.1 - 9.2e-80 267.8 0.0 1.1e-79 267.6 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EMG49669.1 - 5.8e-05 22.2 0.0 8.6e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF692 PF05114.8 EMG49669.1 - 0.052 12.4 0.0 0.089 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF692) Actin PF00022.14 EMG49670.1 - 8.2e-67 225.3 0.0 1e-66 225.0 0.0 1.1 1 0 0 1 1 1 1 Actin LDB19 PF13002.2 EMG49671.1 - 1.5e-63 213.8 0.6 2.6e-63 212.9 0.4 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_C PF02752.17 EMG49671.1 - 6.5e-07 29.5 2.7 0.0008 19.5 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EMG49671.1 - 1.8e-05 24.6 1.0 5.3e-05 23.0 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain zf-BED PF02892.10 EMG49672.1 - 3.5e-07 29.8 1.6 3.9e-07 29.7 0.2 1.8 2 0 0 2 2 2 1 BED zinc finger DASH_Spc19 PF08287.6 EMG49672.1 - 0.063 12.9 1.1 0.14 11.7 0.8 1.5 1 0 0 1 1 1 0 Spc19 Soyouz_module PF14313.1 EMG49672.1 - 0.078 12.5 0.3 0.18 11.4 0.2 1.6 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) DUF605 PF04652.11 EMG49673.1 - 0.75 9.1 21.7 1.1 8.5 15.0 1.3 1 0 0 1 1 1 0 Vta1 like Ribosomal_L44 PF00935.14 EMG49674.1 - 3.7e-34 116.5 10.8 5.5e-34 116.0 7.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L44 PF00935.14 EMG49675.1 - 1.3e-33 114.7 12.2 2e-33 114.2 8.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L33 PF00471.15 EMG49675.1 - 5.4 7.3 10.9 1.3 9.2 0.8 2.8 2 1 0 2 2 2 0 Ribosomal protein L33 Pkinase PF00069.20 EMG49676.1 - 1e-59 201.7 6.4 5.5e-41 140.4 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMG49676.1 - 6.2e-27 94.2 4.8 1.2e-21 76.9 0.0 2.6 2 1 1 3 3 3 2 Protein tyrosine kinase Kdo PF06293.9 EMG49676.1 - 0.00018 20.6 0.1 0.00068 18.7 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMG49676.1 - 0.00033 19.7 0.0 0.00033 19.7 0.0 2.2 3 0 0 3 3 3 1 Kinase-like Pkinase_C PF00433.19 EMG49676.1 - 0.014 15.8 0.3 0.014 15.8 0.2 3.3 2 1 0 2 2 2 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.6 EMG49676.1 - 0.027 13.2 0.1 0.056 12.2 0.1 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 EMG49676.1 - 0.032 13.0 0.0 0.053 12.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EMG49676.1 - 0.082 12.6 7.6 0.13 11.9 0.2 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family tRNA-synt_1d PF00750.14 EMG49676.1 - 4.8 5.8 9.9 0.6 8.8 3.5 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (R) Ytp1 PF10355.4 EMG49677.1 - 6.4e-109 363.3 10.5 6.4e-109 363.3 7.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EMG49677.1 - 3.5e-29 100.4 8.4 3.5e-29 100.4 5.8 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Bul1_C PF04426.7 EMG49678.1 - 9.6e-13 47.9 3.8 1.4e-05 24.4 0.0 2.2 1 1 1 2 2 2 2 Bul1 C terminus Bul1_N PF04425.7 EMG49680.1 - 1.6e-15 56.6 14.8 1.5e-05 23.7 0.3 3.1 1 1 2 3 3 3 3 Bul1 N terminus Arrestin_N PF00339.24 EMG49680.1 - 0.00037 20.3 0.0 0.0017 18.2 0.0 1.9 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF1517 PF07466.6 EMG49682.1 - 2.2 7.2 8.8 3.3 6.6 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Sdh5 PF03937.11 EMG49683.1 - 1.5e-25 88.6 1.6 2.3e-25 88.0 1.1 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase EndoU_bacteria PF14436.1 EMG49683.1 - 0.0044 16.8 0.0 0.0067 16.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial EndoU nuclease EF-hand_6 PF13405.1 EMG49684.1 - 2.8e-13 48.5 3.0 8.1e-05 22.1 0.1 5.4 5 1 1 6 6 6 3 EF-hand domain EF-hand_7 PF13499.1 EMG49684.1 - 1e-12 48.0 8.8 5.7e-06 26.3 0.2 3.5 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EMG49684.1 - 4.9e-12 44.2 4.0 4.8e-05 22.3 0.1 5.4 6 1 0 6 6 6 3 EF hand EF-hand_8 PF13833.1 EMG49684.1 - 3.9e-09 35.9 3.2 1.7e-05 24.3 0.4 4.1 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 EMG49684.1 - 0.0021 17.3 6.0 3.5 7.1 0.1 5.0 5 0 0 5 5 5 1 EF hand EF-hand_9 PF14658.1 EMG49684.1 - 0.0071 16.2 1.1 0.83 9.6 0.1 3.5 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 EMG49684.1 - 0.028 14.4 0.0 14 5.7 0.0 2.8 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EMG49684.1 - 0.03 14.0 0.9 0.41 10.4 0.1 2.8 1 1 3 4 4 4 0 Cytoskeletal-regulatory complex EF hand GH114_assoc PF14741.1 EMG49684.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain HARP PF07443.8 EMG49684.1 - 0.44 9.9 2.8 0.64 9.4 0.1 2.5 3 0 0 3 3 3 0 HepA-related protein (HARP) Ank_2 PF12796.2 EMG49685.1 - 1.3e-10 41.4 0.3 1.3e-08 35.0 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMG49685.1 - 7.7e-10 38.7 0.0 1.2e-06 28.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMG49685.1 - 7.7e-09 35.8 1.1 1.1e-05 25.7 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMG49685.1 - 2.2e-08 33.5 0.2 0.00085 19.3 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 EMG49685.1 - 3.8e-08 32.7 0.0 0.001 18.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat KilA-N PF04383.8 EMG49685.1 - 5.4e-05 22.7 0.1 0.00022 20.7 0.1 2.1 1 0 0 1 1 1 1 KilA-N domain Cas6 PF09559.5 EMG49685.1 - 0.0015 18.3 0.1 0.0076 15.9 0.0 2.1 2 0 0 2 2 2 1 Cas6 Crispr Adeno_PIX PF03955.9 EMG49685.1 - 0.77 10.2 2.0 1.5 9.3 0.3 2.2 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) zf-met PF12874.2 EMG49686.1 - 6.5e-07 29.3 0.5 3.2e-06 27.1 0.6 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type TLP-20 PF06088.6 EMG49686.1 - 0.0041 16.7 2.0 0.006 16.2 1.2 1.5 1 1 0 1 1 1 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) VBS PF08913.5 EMG49686.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Vinculin Binding Site PAPS_reduct PF01507.14 EMG49687.1 - 9e-27 94.0 0.0 1e-23 84.0 0.0 2.6 2 1 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family HLH PF00010.21 EMG49688.1 - 3.6e-16 58.5 0.0 7.8e-16 57.5 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RRP14 PF15459.1 EMG49688.1 - 0.19 11.7 0.9 0.55 10.3 0.0 2.2 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 UPF0061 PF02696.9 EMG49690.1 - 1.1e-117 393.3 0.0 1.3e-117 393.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Glyco_hydro_3 PF00933.16 EMG49690.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 N terminal domain Sec23_trunk PF04811.10 EMG49691.1 - 1.4e-62 211.2 0.0 2.2e-62 210.6 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EMG49691.1 - 2.9e-24 84.4 0.0 9e-24 82.8 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EMG49691.1 - 2.6e-17 63.1 0.0 5.6e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EMG49691.1 - 7.5e-17 60.6 5.0 1.5e-16 59.6 3.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EMG49691.1 - 3.5e-05 23.3 0.0 0.00011 21.7 0.0 1.9 1 0 0 1 1 1 1 Gelsolin repeat COG5 PF10392.4 EMG49692.1 - 8.5e-37 126.0 8.6 1.1e-36 125.6 0.8 3.3 2 1 0 2 2 2 2 Golgi transport complex subunit 5 DUF2011 PF09428.5 EMG49692.1 - 1.1e-26 93.2 19.6 2.1e-26 92.3 13.6 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Ank_2 PF12796.2 EMG49693.1 - 1.5e-43 147.0 3.8 1.2e-19 70.3 0.1 3.4 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EMG49693.1 - 2.9e-29 99.3 0.1 1.3e-11 43.6 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EMG49693.1 - 1e-25 89.1 0.2 5e-06 26.5 0.0 5.5 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMG49693.1 - 1.1e-23 83.1 0.1 1.9e-07 31.4 0.0 5.4 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMG49693.1 - 1.3e-23 80.7 0.5 1.8e-07 30.7 0.1 6.0 6 0 0 6 6 6 5 Ankyrin repeat OCD_Mu_crystall PF02423.10 EMG49694.1 - 1.9e-25 89.2 0.0 2.5e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EMG49694.1 - 2.4e-07 30.9 0.0 6.8e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Mito_carr PF00153.22 EMG49696.1 - 9.7e-52 172.6 0.8 3.1e-16 58.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein BAR PF03114.13 EMG49697.1 - 1.2e-13 51.0 4.3 1.9e-13 50.4 3.0 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EMG49697.1 - 3.9e-12 45.3 0.2 7.1e-12 44.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMG49697.1 - 2.2e-11 43.1 0.1 3.7e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMG49697.1 - 3.4e-10 39.2 0.0 5.4e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 EMG49697.1 - 0.0049 16.1 9.0 0.012 14.8 6.2 1.6 1 1 0 1 1 1 1 Vps5 C terminal like DUF1018 PF06252.7 EMG49697.1 - 0.053 14.0 0.3 0.11 13.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) DUF4319 PF14203.1 EMG49697.1 - 0.12 11.9 1.4 0.35 10.4 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4319) DUF3571 PF12095.3 EMG49697.1 - 0.17 12.1 0.1 0.17 12.1 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3571) DUF641 PF04859.7 EMG49697.1 - 0.24 11.1 3.6 4.1 7.1 0.2 2.9 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) DivIVA PF05103.8 EMG49697.1 - 0.59 10.1 8.0 0.35 10.9 0.2 2.3 2 0 0 2 2 2 0 DivIVA protein Phage_GP20 PF06810.6 EMG49697.1 - 0.7 9.3 10.6 0.37 10.2 0.1 2.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 Baculo_PEP_C PF04513.7 EMG49697.1 - 6.1 6.6 9.0 3.3 7.5 0.1 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DEAD PF00270.24 EMG49698.1 - 1.9e-32 112.1 0.1 2.3e-31 108.5 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Pept_tRNA_hydro PF01195.14 EMG49698.1 - 2.9e-23 82.3 0.0 6.5e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Helicase_C PF00271.26 EMG49698.1 - 8.5e-20 70.4 0.1 2.5e-19 68.9 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMG49698.1 - 6.1e-07 29.4 0.1 1.9e-06 27.8 0.1 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EMG49698.1 - 7.9e-05 22.0 0.0 0.00021 20.7 0.0 1.7 1 0 0 1 1 1 1 SecA DEAD-like domain PhoH PF02562.11 EMG49698.1 - 0.043 13.0 0.4 0.71 9.0 0.0 2.7 3 0 0 3 3 3 0 PhoH-like protein Glyco_hydro_47 PF01532.15 EMG49698.1 - 0.073 11.7 0.5 0.14 10.7 0.4 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 47 Sad1_UNC PF07738.8 EMG49699.1 - 3.4e-38 130.5 0.1 1e-37 128.9 0.1 1.9 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal MFS_1 PF07690.11 EMG49700.1 - 1.1e-31 109.8 26.3 1.1e-31 109.8 18.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG49700.1 - 4.6e-14 51.8 25.0 6.8e-14 51.2 17.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Alk_phosphatase PF00245.15 EMG49701.1 - 4.6e-116 387.9 0.0 5.5e-116 387.7 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EMG49701.1 - 3.9e-05 23.1 0.4 0.00028 20.3 0.1 2.1 2 0 0 2 2 2 1 Metalloenzyme superfamily SH3_9 PF14604.1 EMG49702.1 - 4.9e-10 38.8 0.1 8.6e-10 38.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMG49702.1 - 4.5e-08 32.3 0.2 9.5e-08 31.3 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMG49702.1 - 3e-07 29.8 0.0 5.8e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Aldo_ket_red PF00248.16 EMG49703.1 - 6.5e-49 166.2 0.0 7.7e-49 166.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SpoU_sub_bind PF08032.7 EMG49703.1 - 0.019 15.1 0.4 0.21 11.7 0.0 2.9 3 1 1 4 4 4 0 RNA 2'-O ribose methyltransferase substrate binding Bul1_N PF04425.7 EMG49705.1 - 2.2e-90 303.3 2.9 3.5e-90 302.6 2.0 1.2 1 0 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.7 EMG49705.1 - 4.3e-21 75.3 8.2 3.8e-11 42.6 0.2 3.0 2 1 0 3 3 3 2 Bul1 C terminus Bul1_N PF04425.7 EMG49706.1 - 8.9e-98 327.6 0.6 1.4e-97 327.0 0.4 1.3 1 0 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.7 EMG49706.1 - 2.4e-25 89.2 7.8 6.8e-14 51.7 2.3 3.0 2 1 1 3 3 3 2 Bul1 C terminus PfkB PF00294.19 EMG49707.1 - 3.6e-59 200.3 0.1 4e-59 200.1 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EMG49707.1 - 4e-05 22.9 0.1 6.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase RPA_C PF08784.6 EMG49707.1 - 0.06 13.7 0.5 0.34 11.3 0.1 2.2 2 1 0 2 2 2 0 Replication protein A C terminal DKCLD PF08068.7 EMG49708.1 - 4.3e-31 106.6 0.1 1.8e-30 104.6 0.1 2.1 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EMG49708.1 - 7.7e-22 78.0 4.3 2.2e-20 73.3 0.0 3.4 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EMG49708.1 - 6.4e-21 73.8 0.6 1.3e-20 72.9 0.4 1.5 1 0 0 1 1 1 1 PUA domain HSF_DNA-bind PF00447.12 EMG49709.1 - 7.1e-34 116.0 3.1 7.1e-34 116.0 2.1 3.1 3 0 0 3 3 3 1 HSF-type DNA-binding AOX PF01786.12 EMG49711.1 - 1.4e-80 269.6 0.0 1.6e-80 269.3 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase AOX PF01786.12 EMG49712.1 - 1.9e-86 288.7 0.0 2.2e-86 288.5 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase DUF4248 PF14053.1 EMG49712.1 - 0.026 14.1 0.2 1.1 8.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) Dak1 PF02733.12 EMG49713.1 - 4.8e-113 377.0 0.3 8.2e-113 376.2 0.2 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EMG49713.1 - 3.3e-45 153.8 0.1 6.7e-45 152.8 0.1 1.5 1 0 0 1 1 1 1 DAK2 domain DNA_pol3_delta PF06144.8 EMG49713.1 - 0.00095 18.7 0.2 0.0024 17.4 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit K_oxygenase PF13434.1 EMG49714.1 - 7.4e-11 41.5 0.0 1.1e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EMG49714.1 - 1.1e-07 32.1 0.0 0.0032 17.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMG49714.1 - 0.029 14.7 0.1 2.2 8.7 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMG49714.1 - 0.033 13.0 0.1 1.4 7.7 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Fungal_trans_2 PF11951.3 EMG49715.1 - 2.3e-33 115.3 0.1 2.9e-32 111.7 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG49715.1 - 5e-08 32.7 11.5 1e-07 31.7 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 EMG49715.1 - 0.96 7.6 43.3 1.6 6.8 30.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sugar_tr PF00083.19 EMG49716.1 - 4e-39 134.4 19.6 5e-39 134.1 13.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG49716.1 - 3.7e-22 78.5 30.3 8.7e-18 64.1 13.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 EMG49717.1 - 2.9e-99 332.2 0.6 4e-99 331.8 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG49717.1 - 2e-09 37.2 7.0 3.1e-09 36.5 4.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flocculin_t3 PF13928.1 EMG49718.1 - 2.4e-13 49.9 18.4 2.4e-13 49.9 12.8 2.6 2 2 1 3 3 3 1 Flocculin type 3 repeat DUF202 PF02656.10 EMG49718.1 - 0.96 9.7 3.9 3.1 8.0 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) UCH_1 PF13423.1 EMG49719.1 - 1.2e-41 143.0 11.4 2.1e-41 142.3 7.9 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EMG49719.1 - 8.8e-24 84.6 0.0 1.9e-23 83.5 0.0 1.6 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 EMG49719.1 - 3e-11 42.9 10.7 5.8e-11 42.0 7.4 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 EMG49719.1 - 0.048 13.5 0.1 0.64 9.9 0.1 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat Ribosomal_L37e PF01907.14 EMG49720.1 - 2.5e-22 78.4 10.0 2.5e-22 78.4 6.9 1.6 2 0 0 2 2 2 1 Ribosomal protein L37e DZR PF12773.2 EMG49720.1 - 0.00092 18.9 2.6 0.0013 18.5 1.8 1.2 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 EMG49720.1 - 0.0063 16.2 0.3 0.0081 15.8 0.2 1.3 1 1 0 1 1 1 1 SelR domain zf-C2HC5 PF06221.8 EMG49720.1 - 0.11 12.3 1.8 0.15 11.8 1.2 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-RING_5 PF14634.1 EMG49720.1 - 0.12 12.0 3.3 0.19 11.4 2.3 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-ribbon_3 PF13248.1 EMG49720.1 - 0.15 11.2 3.9 0.48 9.7 2.7 1.8 1 1 1 2 2 2 0 zinc-ribbon domain zinc_ribbon_6 PF14599.1 EMG49720.1 - 0.19 11.5 2.6 0.27 11.0 1.8 1.3 1 0 0 1 1 1 0 Zinc-ribbon GATA PF00320.22 EMG49720.1 - 0.2 11.0 6.3 0.67 9.3 0.9 2.4 1 1 1 2 2 2 0 GATA zinc finger zinc_ribbon_2 PF13240.1 EMG49720.1 - 1.1 8.8 6.1 34 4.0 0.2 2.2 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4 PF00097.20 EMG49720.1 - 1.2 8.8 5.4 2 8.1 3.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMG49720.1 - 1.5 8.9 5.3 2.4 8.2 3.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ISL3 PF14690.1 EMG49720.1 - 5.1 7.2 7.6 1.5 8.9 0.4 2.6 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 PAP2 PF01569.16 EMG49721.1 - 1.8e-21 76.1 0.9 2.5e-21 75.6 0.2 1.6 2 0 0 2 2 2 1 PAP2 superfamily ABC2_membrane_4 PF12730.2 EMG49721.1 - 0.031 13.4 5.2 0.38 9.8 2.4 2.5 1 1 1 2 2 2 0 ABC-2 family transporter protein Fungal_trans_2 PF11951.3 EMG49722.1 - 1.8e-34 119.0 0.0 2.4e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG49722.1 - 6.8e-09 35.5 8.7 1.2e-08 34.7 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LCD1 PF09798.4 EMG49723.1 - 4.2e-117 391.8 24.0 4.9e-117 391.5 16.6 1.0 1 0 0 1 1 1 1 DNA damage checkpoint protein DUF2360 PF10152.4 EMG49723.1 - 0.0036 17.5 8.4 0.0036 17.5 5.8 2.7 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein (DUF2360) NPHI_C PF08469.5 EMG49723.1 - 0.005 16.7 0.3 0.015 15.1 0.2 1.8 1 0 0 1 1 1 1 Nucleoside triphosphatase I C-terminal TMF_TATA_bd PF12325.3 EMG49723.1 - 0.012 15.3 8.0 0.043 13.5 4.7 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF947 PF06102.7 EMG49723.1 - 0.044 13.5 2.5 0.097 12.4 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF947) ACCA PF03255.9 EMG49723.1 - 0.26 10.8 2.0 0.74 9.3 1.4 1.9 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF342 PF03961.8 EMG49723.1 - 0.89 7.8 4.5 1.5 7.1 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) EMG1 PF03587.9 EMG49724.1 - 5.4e-75 251.1 0.0 6.4e-75 250.8 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DUF1180 PF06679.7 EMG49724.1 - 1.1 9.1 4.0 2 8.3 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Tantalus PF15386.1 EMG49725.1 - 0.055 13.2 0.3 0.13 12.0 0.2 1.6 1 0 0 1 1 1 0 Drosophila Tantalus-like Pkinase PF00069.20 EMG49726.1 - 7.7e-75 251.3 0.0 2.1e-74 249.9 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG49726.1 - 1.3e-37 129.3 0.0 2.3e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG49726.1 - 6e-07 28.6 0.1 4.9e-05 22.4 0.0 2.6 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EMG49726.1 - 0.022 14.5 2.0 0.08 12.6 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF501 PF04417.7 EMG49726.1 - 0.071 12.9 2.1 0.21 11.4 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF501) KH_1 PF00013.24 EMG49727.1 - 0.0022 17.5 0.0 0.0085 15.7 0.0 1.9 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 EMG49727.1 - 0.046 13.3 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 KH domain Med11 PF10280.4 EMG49728.1 - 0.023 14.7 0.4 1 9.3 0.0 2.8 2 0 0 2 2 2 0 Mediator complex protein MRC1 PF09444.5 EMG49729.1 - 5.1e-41 140.3 14.4 5.1e-41 140.3 10.0 7.5 6 3 2 8 8 8 1 MRC1-like domain S-AdoMet_synt_C PF02773.11 EMG49730.1 - 7.9e-77 255.6 0.2 1.4e-76 254.8 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EMG49730.1 - 2e-48 163.2 0.0 3.6e-48 162.4 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EMG49730.1 - 3e-43 146.0 1.3 3.5e-43 145.8 0.1 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Rad60-SLD PF11976.3 EMG49732.1 - 2.5e-18 65.5 0.3 3.4e-18 65.1 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EMG49732.1 - 1.1e-06 27.9 0.1 1.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family SH3_1 PF00018.23 EMG49732.1 - 0.053 12.9 0.1 0.087 12.2 0.1 1.4 1 0 0 1 1 1 0 SH3 domain FAINT PF04385.10 EMG49732.1 - 0.13 12.1 0.9 0.17 11.7 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function, DUF529 5TM-5TMR_LYT PF07694.7 EMG49733.1 - 0.028 13.7 0.6 0.028 13.7 0.4 3.0 5 0 0 5 5 5 0 5TMR of 5TMR-LYT FHA PF00498.21 EMG49734.1 - 0.00074 19.5 0.1 0.0031 17.6 0.1 2.1 1 0 0 1 1 1 1 FHA domain EB1 PF03271.12 EMG49735.1 - 9.7e-15 54.3 0.6 2.1e-14 53.2 0.4 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EMG49735.1 - 4.5e-07 29.8 0.8 4.5e-07 29.8 0.5 1.5 2 0 0 2 2 2 1 Calponin homology (CH) domain NHR2 PF08788.6 EMG49735.1 - 0.014 14.9 0.4 0.03 13.7 0.0 1.8 2 0 0 2 2 2 0 NHR2 domain like YadA_head PF05658.9 EMG49736.1 - 0.0034 17.5 11.7 0.017 15.3 7.6 2.8 1 1 0 1 1 1 1 Head domain of trimeric autotransporter adhesin CobT PF06213.7 EMG49736.1 - 0.016 14.3 7.5 0.02 14.0 5.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.5 EMG49736.1 - 0.098 11.7 16.3 0.12 11.4 11.3 1.1 1 0 0 1 1 1 0 BUD22 Plasmodium_Vir PF05795.6 EMG49736.1 - 0.19 10.8 6.6 0.3 10.2 4.6 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Nop14 PF04147.7 EMG49736.1 - 0.7 7.7 10.6 0.87 7.4 7.3 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EMG49736.1 - 2.2 6.1 7.4 2.9 5.8 5.1 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 EMG49736.1 - 3 7.0 11.3 3.9 6.6 7.9 1.1 1 0 0 1 1 1 0 SDA1 Hid1 PF12722.2 EMG49736.1 - 5 4.6 10.2 5.5 4.5 7.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RRM_5 PF13893.1 EMG49737.1 - 2e-07 30.7 0.1 4.2e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMG49737.1 - 0.026 14.1 0.1 0.068 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAPA-1 PF04795.7 EMG49737.1 - 0.14 12.9 6.0 0.18 12.5 3.4 1.7 1 1 0 1 1 1 0 PAPA-1-like conserved region Oxidored_FMN PF00724.15 EMG49738.1 - 1.9e-47 161.9 0.0 2.3e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DEAD PF00270.24 EMG49739.1 - 2.6e-44 150.6 0.0 9.8e-44 148.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG49739.1 - 1.2e-25 89.1 0.1 2.8e-25 87.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PSP1 PF04468.7 EMG49740.1 - 1.2e-28 98.9 0.6 3.1e-28 97.5 0.4 1.8 1 0 0 1 1 1 1 PSP1 C-terminal conserved region CDP-OH_P_transf PF01066.16 EMG49742.1 - 3.6e-12 46.4 4.3 3.6e-12 46.4 3.0 1.6 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Hap4_Hap_bind PF10297.4 EMG49744.1 - 2.9e-09 36.4 7.4 7.1e-09 35.2 5.1 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 EMG49744.1 - 5.4e-06 26.2 19.6 7.4e-05 22.6 7.7 2.8 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 EMG49744.1 - 0.15 11.9 21.6 0.16 11.8 7.6 3.0 1 1 1 2 2 2 0 Basic region leucine zipper Herpes_UL6 PF01763.11 EMG49744.1 - 0.21 9.7 5.2 0.052 11.7 0.4 2.0 2 0 0 2 2 2 0 Herpesvirus UL6 like PP2C_C PF07830.8 EMG49744.1 - 6 7.0 6.9 0.91 9.6 0.0 2.9 4 0 0 4 4 4 0 Protein serine/threonine phosphatase 2C, C-terminal domain NIF PF03031.13 EMG49745.1 - 7.9e-41 139.3 0.1 1.4e-40 138.5 0.1 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ARD PF03079.9 EMG49747.1 - 4e-42 143.8 2.7 4.7e-42 143.6 1.9 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EMG49747.1 - 1e-08 34.5 0.0 1.7e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EMG49747.1 - 3.8e-06 26.6 0.0 5.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EMG49747.1 - 0.00031 20.1 0.0 0.00041 19.8 0.0 1.3 1 0 0 1 1 1 1 Cupin Aromatic_hydrox PF11723.3 EMG49747.1 - 0.058 12.6 0.4 0.086 12.1 0.3 1.2 1 0 0 1 1 1 0 Homotrimeric ring hydroxylase BAR_2 PF10455.4 EMG49748.1 - 1.1e-95 319.8 10.4 1.4e-95 319.5 7.2 1.0 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking PhaP_Bmeg PF09602.5 EMG49748.1 - 0.025 14.4 0.8 0.025 14.4 0.6 2.0 2 1 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) HSP9_HSP12 PF04119.7 EMG49748.1 - 0.04 14.0 0.6 0.1 12.6 0.4 1.7 1 0 0 1 1 1 0 Heat shock protein 9/12 Syntaxin_2 PF14523.1 EMG49748.1 - 0.52 10.3 6.3 0.68 10.0 0.3 3.3 2 1 0 2 2 2 0 Syntaxin-like protein Fib_alpha PF08702.5 EMG49748.1 - 5.5 7.1 9.7 0.29 11.2 1.2 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family PRP38 PF03371.10 EMG49749.1 - 1.4e-54 184.2 2.0 1.8e-54 183.9 1.4 1.1 1 0 0 1 1 1 1 PRP38 family EamA PF00892.15 EMG49750.1 - 9e-10 38.6 31.5 8.7e-05 22.5 11.2 3.1 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EMG49750.1 - 3.6e-06 27.1 28.2 5.6e-05 23.3 2.6 2.9 3 1 0 3 3 3 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 EMG49750.1 - 2.7e-05 23.4 5.4 9.3e-05 21.6 0.1 2.7 3 1 0 3 3 3 1 Nucleotide-sugar transporter TPT PF03151.11 EMG49750.1 - 6.5e-05 22.6 27.5 0.0012 18.4 11.4 3.3 2 2 1 3 3 3 2 Triose-phosphate Transporter family UAA PF08449.6 EMG49750.1 - 0.00084 18.3 13.2 0.0014 17.5 9.2 1.3 1 1 0 1 1 1 1 UAA transporter family ISK_Channel PF02060.10 EMG49750.1 - 0.022 14.3 0.7 0.15 11.6 0.2 2.2 2 0 0 2 2 2 0 Slow voltage-gated potassium channel Ycf1 PF05758.7 EMG49750.1 - 2.7 5.5 6.8 3.7 5.1 4.7 1.1 1 0 0 1 1 1 0 Ycf1 PDZ_2 PF13180.1 EMG49751.1 - 2.7e-08 33.5 0.1 5.6e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 EMG49751.1 - 0.0007 19.5 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.19 EMG49751.1 - 0.031 14.4 0.1 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) DDOST_48kD PF03345.9 EMG49752.1 - 2.4e-117 392.0 4.7 9.7e-116 386.7 3.3 2.0 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Zn_peptidase_2 PF04298.7 EMG49752.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Arf PF00025.16 EMG49753.1 - 5.7e-37 126.6 3.7 2e-28 98.7 0.2 2.4 1 1 1 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 EMG49753.1 - 2.3e-13 49.6 2.1 2e-08 33.3 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EMG49753.1 - 1.7e-09 37.2 0.7 2.5e-08 33.5 0.0 2.3 1 1 1 2 2 2 1 Ras family Miro PF08477.8 EMG49753.1 - 4.1e-09 36.9 1.1 6.3e-08 33.1 0.8 2.7 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EMG49753.1 - 1.4e-08 34.3 0.2 4e-08 32.9 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EMG49753.1 - 1e-07 31.3 3.7 0.00067 18.9 0.0 2.8 2 1 1 3 3 3 2 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EMG49753.1 - 5.3e-07 29.5 0.3 1.1e-06 28.5 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMG49753.1 - 1.2e-06 27.9 0.4 3.4e-06 26.3 0.2 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EMG49753.1 - 0.0003 20.9 0.0 0.00052 20.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 EMG49753.1 - 0.014 14.3 0.3 0.025 13.6 0.2 1.4 1 0 0 1 1 1 0 Septin ABC_tran PF00005.22 EMG49753.1 - 0.086 13.1 0.1 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Diacid_rec PF05651.8 EMG49753.1 - 0.091 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative sugar diacid recognition FtsK_SpoIIIE PF01580.13 EMG49753.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.1 EMG49753.1 - 0.13 12.5 4.3 0.17 12.2 3.0 1.3 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.13 EMG49754.1 - 1.6e-45 154.9 8.8 1.6e-45 154.9 6.1 1.5 2 0 0 2 2 2 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 EMG49754.1 - 2.8e-07 30.5 0.0 5.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMG49754.1 - 1.7e-05 25.6 0.2 7.1e-05 23.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMG49754.1 - 2.5e-05 24.6 0.4 9e-05 22.7 0.1 2.2 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 EMG49754.1 - 5.4e-05 22.5 5.3 0.00013 21.3 0.4 2.9 1 1 1 2 2 2 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 EMG49754.1 - 0.0021 17.1 0.0 0.0055 15.8 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin T2SE PF00437.15 EMG49754.1 - 0.015 14.2 0.1 0.025 13.4 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ADK PF00406.17 EMG49754.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Adenylate kinase Arf PF00025.16 EMG49754.1 - 0.016 14.4 0.0 0.036 13.2 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_22 PF13401.1 EMG49754.1 - 0.019 15.1 0.0 0.035 14.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EMG49754.1 - 0.019 14.9 0.2 0.054 13.4 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 EMG49754.1 - 0.027 14.3 1.5 0.3 11.0 0.0 2.9 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.1 EMG49754.1 - 0.035 14.1 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.15 EMG49754.1 - 0.047 13.3 0.0 0.095 12.3 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase MutS_V PF00488.16 EMG49754.1 - 0.088 12.2 0.1 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 MutS domain V WD40 PF00400.27 EMG49755.1 - 1.5e-45 151.4 12.0 2.3e-10 39.9 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EMG49755.1 - 1e-07 31.8 2.8 0.0051 16.5 0.2 3.7 2 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EMG49755.1 - 0.049 12.7 0.1 2.9 6.9 0.0 3.0 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal AvrPtoB-E3_ubiq PF09046.5 EMG49755.1 - 0.11 12.5 0.0 0.43 10.5 0.0 2.1 2 0 0 2 2 2 0 AvrPtoB E3 ubiquitin ligase SWIRM PF04433.12 EMG49756.1 - 9.5e-19 67.3 0.4 4.4e-18 65.2 0.0 2.2 2 0 0 2 2 2 1 SWIRM domain ZZ PF00569.12 EMG49756.1 - 4.2e-14 51.8 7.1 7.6e-14 50.9 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EMG49756.1 - 1.5e-10 40.9 0.0 4.3e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMG49756.1 - 1.5e-06 28.2 0.0 1.5e-06 28.2 0.0 2.1 3 0 0 3 3 3 1 Myb-like DNA-binding domain DnaB_2 PF07261.6 EMG49756.1 - 0.079 12.5 1.9 0.14 11.7 0.1 2.3 3 0 0 3 3 3 0 Replication initiation and membrane attachment Baculo_IE-1 PF05290.6 EMG49756.1 - 0.18 11.5 3.0 0.47 10.1 2.0 1.7 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) TLD PF07534.11 EMG49757.1 - 5.7e-26 91.1 3.1 4.2e-23 81.8 2.3 2.3 1 1 1 2 2 2 2 TLD NUC153 PF08159.7 EMG49758.1 - 3.5e-14 52.0 3.5 3.5e-14 52.0 2.4 3.2 3 0 0 3 3 3 2 NUC153 domain HLH PF00010.21 EMG49760.1 - 2.1e-14 52.9 0.8 5.5e-14 51.5 0.5 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Cgr1 PF03879.9 EMG49761.1 - 3.7e-37 126.8 31.2 4.3e-37 126.6 21.6 1.0 1 0 0 1 1 1 1 Cgr1 family DUF342 PF03961.8 EMG49761.1 - 1.6 7.0 9.5 1.7 6.9 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PRP1_N PF06424.7 EMG49761.1 - 3.4 7.9 11.5 4.9 7.4 8.0 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Pex24p PF06398.6 EMG49762.1 - 6.6e-79 265.2 15.4 8.1e-79 265.0 10.7 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin FAD_binding_8 PF08022.7 EMG49763.1 - 4.7e-23 81.0 0.1 1e-22 79.9 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EMG49763.1 - 1e-18 67.7 0.0 2.2e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMG49763.1 - 3.4e-16 59.4 14.1 3.4e-16 59.4 9.8 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EMG49763.1 - 0.026 15.0 0.0 0.13 12.8 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Ribosomal_L7Ae PF01248.21 EMG49764.1 - 4.8e-23 80.4 0.6 8e-23 79.7 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EMG49764.1 - 0.0027 17.5 0.1 0.0043 16.8 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 RRM_6 PF14259.1 EMG49765.1 - 5.1e-11 42.3 0.5 1.2e-08 34.8 0.0 3.5 2 2 1 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMG49765.1 - 2.3e-10 39.9 1.4 2.9e-08 33.2 0.1 3.7 3 1 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG49765.1 - 0.041 13.7 0.1 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF320 PF03777.8 EMG49765.1 - 0.13 12.0 0.6 16 5.3 0.0 2.5 2 0 0 2 2 2 0 Small secreted domain (DUF320) Ribosomal_L2_C PF03947.13 EMG49766.1 - 2.5e-39 134.0 2.8 2.5e-39 134.0 2.0 1.4 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EMG49766.1 - 5.4e-15 55.1 0.1 1.2e-14 54.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SpoA PF01052.15 EMG49766.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Surface presentation of antigens (SPOA) Ribosomal_S17e PF00833.13 EMG49767.1 - 2e-55 185.7 0.6 2.4e-55 185.5 0.4 1.0 1 0 0 1 1 1 1 Ribosomal S17 UPF0262 PF06793.7 EMG49767.1 - 0.0069 16.1 0.1 0.035 13.8 0.1 1.9 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0262) Pet127 PF08634.5 EMG49768.1 - 1.4e-92 309.7 1.6 1.4e-92 309.7 1.1 2.4 3 0 0 3 3 3 1 Mitochondrial protein Pet127 U3_assoc_6 PF08640.6 EMG49769.1 - 3.5e-32 110.0 3.1 1.2e-30 105.0 0.0 2.7 2 1 0 2 2 2 2 U3 small nucleolar RNA-associated protein 6 DUF2250 PF10007.4 EMG49769.1 - 0.0047 16.8 7.5 11 6.0 0.1 4.2 4 0 0 4 4 4 3 Uncharacterized protein conserved in archaea (DUF2250) NRDE-2 PF08424.5 EMG49769.1 - 0.019 13.8 4.2 0.54 9.0 1.2 2.9 2 1 0 2 2 2 0 NRDE-2, necessary for RNA interference Suf PF05843.9 EMG49769.1 - 0.038 13.7 4.3 0.43 10.2 1.6 3.3 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EMG49769.1 - 0.047 14.3 0.0 2.3 9.1 0.0 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat Nup96 PF12110.3 EMG49770.1 - 0.034 13.2 0.0 0.038 13.0 0.0 1.1 1 0 0 1 1 1 0 Nuclear protein 96 RIO1 PF01163.17 EMG49771.1 - 4e-74 248.0 1.3 4e-74 248.0 0.9 2.2 2 0 0 2 2 2 1 RIO1 family EMP24_GP25L PF01105.19 EMG49771.1 - 1.7e-44 151.7 2.6 1.7e-44 151.7 1.8 1.9 2 1 0 2 2 2 1 emp24/gp25L/p24 family/GOLD APH PF01636.18 EMG49771.1 - 0.0031 17.3 0.1 1.2 8.8 0.0 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family SDA1 PF05285.7 EMG49771.1 - 2.3 7.4 33.4 0.24 10.6 19.3 2.0 2 0 0 2 2 2 0 SDA1 ThiF PF00899.16 EMG49772.1 - 8.4e-39 132.5 0.1 1.4e-38 131.8 0.1 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EMG49772.1 - 2.2e-25 88.0 0.1 5.1e-25 86.8 0.1 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EMG49772.1 - 1.6e-15 57.4 0.0 3.1e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Herpes_BLRF2 PF05812.7 EMG49772.1 - 0.0014 18.4 0.5 0.0029 17.4 0.3 1.5 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein Shikimate_DH PF01488.15 EMG49772.1 - 0.0021 18.1 0.1 0.01 15.9 0.1 2.1 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EMG49772.1 - 0.017 15.3 0.0 0.053 13.7 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Rad60-SLD PF11976.3 EMG49774.1 - 4.2e-21 74.4 3.4 5.7e-21 73.9 1.2 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.3 EMG49774.1 - 0.0031 17.3 0.0 0.009 15.9 0.0 1.8 1 0 0 1 1 1 1 GLUT4 regulating protein TUG CD99L2 PF12301.3 EMG49774.1 - 0.15 11.7 9.8 0.019 14.6 3.2 2.0 2 0 0 2 2 2 0 CD99 antigen like protein 2 Kei1 PF08552.6 EMG49775.1 - 1.9e-11 43.9 0.7 2.5e-11 43.6 0.5 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF475 PF04332.10 EMG49775.1 - 0.015 14.8 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF475) MRP-S25 PF13741.1 EMG49776.1 - 2e-91 305.5 5.0 2.6e-91 305.2 3.5 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 EMG49776.1 - 1.4e-06 28.1 0.0 4.2e-05 23.4 0.0 2.5 2 0 0 2 2 2 1 Mitochondrial ribosomal protein S23 PPR_2 PF13041.1 EMG49777.1 - 0.31 11.0 2.5 0.42 10.6 0.0 2.5 2 0 0 2 2 2 0 PPR repeat family ATP-synt_S1 PF05827.7 EMG49778.1 - 5.7e-48 163.6 0.0 6.4e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) DAO PF01266.19 EMG49779.1 - 5e-58 196.7 0.0 1.8e-57 194.8 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMG49779.1 - 5.1e-06 26.4 0.2 1.7e-05 24.7 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Prothymosin PF03247.9 EMG49779.1 - 0.0019 18.3 16.8 0.0019 18.3 11.6 2.3 2 0 0 2 2 2 1 Prothymosin/parathymosin family NAD_binding_9 PF13454.1 EMG49779.1 - 0.0021 17.8 0.1 0.0091 15.7 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 EMG49779.1 - 0.0033 16.5 0.1 0.0057 15.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Strep_67kDa_ant PF06100.6 EMG49779.1 - 0.066 11.5 0.2 0.12 10.7 0.1 1.4 2 0 0 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Nop14 PF04147.7 EMG49779.1 - 0.066 11.1 14.3 0.11 10.4 9.9 1.3 1 0 0 1 1 1 0 Nop14-like family Trp_halogenase PF04820.9 EMG49779.1 - 0.13 10.8 0.1 0.21 10.1 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Daxx PF03344.10 EMG49779.1 - 0.16 10.4 9.9 0.27 9.6 6.9 1.3 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 EMG49779.1 - 1 8.3 15.0 2 7.3 10.4 1.4 1 0 0 1 1 1 0 BUD22 Hid1 PF12722.2 EMG49779.1 - 2 5.9 4.8 2.5 5.6 3.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nucleoplasmin PF03066.10 EMG49779.1 - 3.6 7.0 20.4 4.3 6.8 10.6 2.3 2 0 0 2 2 2 0 Nucleoplasmin Herpes_LMP1 PF05297.6 EMG49779.1 - 7.5 5.3 7.4 10 4.9 4.3 1.7 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) zf-C2H2 PF00096.21 EMG49780.1 - 2.1e-11 43.4 19.4 2.8e-06 27.3 1.3 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMG49780.1 - 5.6e-09 35.7 17.7 4.7e-05 23.4 2.1 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMG49780.1 - 2.2e-07 30.8 19.3 1.1e-06 28.6 3.1 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMG49780.1 - 0.00013 22.0 8.2 0.0017 18.4 0.6 5.0 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMG49780.1 - 0.00042 20.1 6.0 0.0077 16.1 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.10 EMG49780.1 - 0.0071 16.0 0.4 0.0071 16.0 0.3 2.9 3 0 0 3 3 3 2 BED zinc finger Evr1_Alr PF04777.8 EMG49780.1 - 0.0093 15.8 3.7 0.098 12.5 0.2 3.0 1 1 1 2 2 2 1 Erv1 / Alr family PyrI_C PF02748.10 EMG49780.1 - 0.048 13.0 1.0 0.2 11.0 0.1 2.3 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Di19 PF05605.7 EMG49780.1 - 1.3 9.1 4.9 3.9 7.6 3.4 1.8 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding G6PD_C PF02781.11 EMG49781.1 - 2.7e-133 443.3 0.0 3.4e-133 443.0 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EMG49781.1 - 1.4e-61 207.9 0.0 2.1e-61 207.3 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain 6PF2K PF01591.13 EMG49783.1 - 4.5e-78 261.3 0.1 1.5e-77 259.6 0.0 1.9 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EMG49783.1 - 3.5e-24 85.7 0.1 9.1e-24 84.3 0.0 1.8 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EMG49783.1 - 0.00098 19.0 0.1 0.0034 17.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMG49783.1 - 0.0097 16.7 0.0 0.044 14.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain DUF3822 PF12864.2 EMG49783.1 - 0.013 14.7 0.0 0.032 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3822) Fe_hyd_lg_C PF02906.9 EMG49784.1 - 2.4e-72 243.5 0.0 3.5e-72 243.0 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Ytp1 PF10355.4 EMG49785.1 - 2.1e-84 282.9 12.4 3.1e-84 282.3 8.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF4064 PF13273.1 EMG49785.1 - 5.3 7.2 14.1 0.56 10.3 0.6 4.2 3 2 2 5 5 5 0 Protein of unknown function (DUF4064) Peptidase_S8 PF00082.17 EMG49786.1 - 6.9e-54 182.9 4.4 1.2e-53 182.1 3.1 1.4 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 EMG49786.1 - 3.9e-24 84.2 0.1 8.5e-24 83.1 0.1 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain DUF912 PF06024.7 EMG49786.1 - 0.11 12.5 0.0 0.11 12.5 0.0 3.6 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RNA_pol_Rpb1_5 PF04998.12 EMG49787.1 - 5e-98 327.7 0.0 6.5e-97 324.1 0.0 2.7 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EMG49787.1 - 5.2e-65 218.4 0.0 2e-64 216.5 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EMG49787.1 - 3.4e-38 130.8 0.6 5.3e-37 126.9 0.0 3.3 4 0 0 4 4 4 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EMG49787.1 - 1.5e-24 85.7 0.1 1.5e-23 82.6 0.0 2.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.7 EMG49787.1 - 2.7e-21 76.1 0.1 2.7e-21 76.1 0.1 3.9 4 0 0 4 4 4 2 RNA polymerase Rpb1, domain 1 CDC45 PF02724.9 EMG49787.1 - 0.00052 18.1 8.7 0.00052 18.1 6.1 2.2 2 0 0 2 2 2 1 CDC45-like protein SIR2 PF02146.12 EMG49788.1 - 2.1e-62 210.0 0.0 3.1e-62 209.4 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EMG49788.1 - 2.4e-24 85.6 2.7 1.7e-12 47.1 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EMG49788.1 - 0.0011 18.7 0.0 0.45 10.2 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF1387 PF07139.6 EMG49788.1 - 0.065 12.8 4.4 0.098 12.2 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Zn_Tnp_IS1595 PF12760.2 EMG49788.1 - 0.17 11.7 0.2 0.4 10.5 0.0 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain PBP1_TM PF14812.1 EMG49788.1 - 1.1 9.6 4.2 3.6 7.9 2.9 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Methyltransf_16 PF10294.4 EMG49789.1 - 9.3e-06 25.2 0.0 0.0011 18.4 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_31 PF13847.1 EMG49789.1 - 0.0019 17.7 0.4 0.031 13.8 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMG49789.1 - 0.019 14.7 0.0 0.039 13.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain COX4 PF02936.9 EMG49790.1 - 2.3e-31 108.4 0.0 2.8e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Fer4 PF00037.22 EMG49791.1 - 8.3e-14 50.5 16.9 3.3e-08 32.8 2.8 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EMG49791.1 - 3.6e-12 46.4 10.7 7.1e-12 45.5 7.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EMG49791.1 - 1.6e-10 40.6 23.7 1.8e-08 34.0 8.6 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 EMG49791.1 - 5.5e-10 39.8 10.5 3.2e-05 24.5 0.9 2.7 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.1 EMG49791.1 - 1.4e-09 37.7 4.3 4.6e-05 23.3 0.5 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EMG49791.1 - 2.9e-09 37.0 12.3 5e-09 36.2 8.0 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EMG49791.1 - 2.3e-08 33.7 32.8 1.7e-05 24.5 8.8 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 EMG49791.1 - 1e-07 31.4 14.5 0.00041 20.0 1.5 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EMG49791.1 - 4.2e-07 29.7 12.8 0.00059 19.9 2.1 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EMG49791.1 - 5.9e-07 29.0 17.4 0.0013 18.5 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EMG49791.1 - 5.5e-06 26.6 11.2 0.00062 20.0 7.9 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 EMG49791.1 - 1.6e-05 25.2 9.4 0.012 16.0 0.5 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 EMG49791.1 - 0.0062 17.0 13.0 0.27 11.8 1.3 2.8 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.1 EMG49791.1 - 0.0084 16.4 15.7 0.31 11.4 3.2 2.9 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 EMG49791.1 - 0.016 15.7 17.5 0.042 14.4 2.8 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EMG49791.1 - 0.099 12.7 6.1 0.25 11.4 0.1 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain C2 PF00168.25 EMG49792.1 - 1.3e-56 188.4 1.8 3.3e-18 65.3 0.1 4.5 4 0 0 4 4 4 4 C2 domain Vfa1 PF08432.5 EMG49792.1 - 0.098 12.6 12.6 0.2 11.6 8.7 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RNA_pol_3_Rpc31 PF11705.3 EMG49792.1 - 0.13 12.2 12.9 0.23 11.3 9.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 APG6 PF04111.7 EMG49792.1 - 0.18 10.8 15.4 0.3 10.0 10.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3810 PF12725.2 EMG49792.1 - 6.7 5.4 13.9 0.016 14.1 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Abhydrolase_6 PF12697.2 EMG49793.1 - 3.8e-32 112.0 0.0 5e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMG49793.1 - 1.5e-17 63.8 0.0 1.4e-16 60.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMG49793.1 - 1.3e-15 57.3 0.0 3.9e-15 55.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EMG49793.1 - 0.00016 21.3 0.0 0.00026 20.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 EMG49793.1 - 0.0014 18.2 0.0 0.0018 17.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EMG49793.1 - 0.0057 16.4 0.0 0.0099 15.7 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EMG49793.1 - 0.024 13.8 0.0 0.062 12.5 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.15 EMG49793.1 - 0.071 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.2 EMG49793.1 - 0.093 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme CN_hydrolase PF00795.17 EMG49794.1 - 3.3e-31 108.0 0.0 3.8e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase YoaP PF14268.1 EMG49794.1 - 2.2 7.5 4.4 0.49 9.6 0.6 1.7 2 0 0 2 2 2 0 YoaP-like TPX2 PF06886.6 EMG49795.1 - 1.3 9.1 7.8 28 4.8 0.0 3.0 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) Cohesin_load PF10345.4 EMG49796.1 - 9e-108 361.0 31.5 1.3e-107 360.5 21.8 1.2 1 0 0 1 1 1 1 Cohesin loading factor PFU PF09070.6 EMG49796.1 - 0.055 13.4 1.8 0.18 11.8 0.3 2.7 2 0 0 2 2 2 0 PFU (PLAA family ubiquitin binding) TPR_12 PF13424.1 EMG49796.1 - 0.33 10.9 9.7 4 7.4 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMG49796.1 - 1.6 8.8 10.7 33 4.7 1.7 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMG49796.1 - 1.9 8.4 15.3 4.6 7.2 0.9 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Myotub-related PF06602.9 EMG49797.1 - 7e-121 403.3 0.2 1.1e-120 402.6 0.1 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EMG49797.1 - 0.0051 17.0 0.0 0.01 16.0 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EMG49797.1 - 0.0075 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EMG49797.1 - 0.034 13.7 0.0 0.11 12.0 0.0 1.9 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain SDA1 PF05285.7 EMG49798.1 - 0.0024 17.1 20.7 0.0062 15.8 14.3 1.7 1 0 0 1 1 1 1 SDA1 WD40 PF00400.27 EMG49798.1 - 0.0039 17.0 3.0 6.4 6.8 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat Nop14 PF04147.7 EMG49798.1 - 2.6 5.8 24.0 1.9 6.3 14.4 2.0 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.9 EMG49798.1 - 3.7 5.4 17.0 6.9 4.5 11.8 1.4 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 EMG49798.1 - 8.3 5.9 29.2 0.75 9.3 16.5 1.9 2 0 0 2 2 2 0 YL1 nuclear protein NAD_binding_8 PF13450.1 EMG49799.1 - 8.8e-12 44.8 0.0 1.9e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMG49799.1 - 0.00032 19.7 0.0 0.00048 19.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EMG49799.1 - 0.00039 19.6 0.0 0.0019 17.3 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Mqo PF06039.10 EMG49799.1 - 0.00039 18.7 0.0 0.0069 14.6 0.0 2.2 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.22 EMG49799.1 - 0.00087 19.6 0.0 0.51 10.7 0.0 3.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMG49799.1 - 0.00094 19.2 0.0 0.021 14.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMG49799.1 - 0.0012 18.0 0.0 0.0029 16.7 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase TBP PF00352.16 EMG49800.1 - 9.5e-69 226.8 0.1 9e-34 114.7 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EMG49800.1 - 0.00027 20.9 0.7 0.86 9.7 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF3378) ABC_membrane PF00664.18 EMG49801.1 - 3e-62 210.5 37.2 2.6e-33 115.5 8.9 2.6 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMG49801.1 - 2e-49 167.3 0.2 8.4e-27 94.1 0.0 3.0 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.14 EMG49801.1 - 2.6e-10 39.9 13.1 0.00022 20.5 2.3 4.5 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMG49801.1 - 1.4e-07 31.8 4.9 0.028 14.3 0.2 5.0 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EMG49801.1 - 1.9e-07 31.2 0.3 0.012 15.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EMG49801.1 - 8.7e-07 28.3 1.1 0.0023 17.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EMG49801.1 - 1.4e-06 27.5 0.0 0.0017 17.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EMG49801.1 - 1.2e-05 25.2 3.1 0.1 12.5 0.0 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_23 PF13476.1 EMG49801.1 - 4.7e-05 23.8 8.1 0.15 12.3 4.3 3.5 2 1 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EMG49801.1 - 0.00055 19.4 0.2 0.26 10.6 0.1 2.9 3 0 0 3 3 3 1 AAA-like domain AAA_25 PF13481.1 EMG49801.1 - 0.0011 18.4 0.0 1.7 7.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMG49801.1 - 0.0019 18.3 4.1 0.47 10.5 0.0 3.7 3 1 0 3 3 2 1 AAA domain Miro PF08477.8 EMG49801.1 - 0.0021 18.5 6.7 0.19 12.2 0.0 3.8 4 0 0 4 4 3 2 Miro-like protein DNA_ligase_aden PF01653.13 EMG49801.1 - 0.0021 17.0 0.1 0.004 16.1 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain T2SE PF00437.15 EMG49801.1 - 0.0047 15.8 0.1 1.8 7.3 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.12 EMG49801.1 - 0.008 16.0 1.9 1.3 8.7 0.1 3.0 2 0 0 2 2 2 1 Domain of unknown function DUF87 ABC_ATPase PF09818.4 EMG49801.1 - 0.011 14.3 1.5 1.5 7.3 0.4 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class ArgK PF03308.11 EMG49801.1 - 0.021 13.6 0.2 2.4 6.8 0.0 2.4 2 0 0 2 2 2 0 ArgK protein AAA_30 PF13604.1 EMG49801.1 - 0.021 14.3 3.4 2 7.9 0.5 3.2 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EMG49801.1 - 0.033 13.0 0.2 2.6 6.8 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 EMG49801.1 - 0.034 13.6 0.0 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EMG49801.1 - 0.035 13.2 0.1 6.5 5.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF815 PF05673.8 EMG49801.1 - 0.049 12.5 0.0 4 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 EMG49801.1 - 0.055 13.7 0.1 10 6.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 EMG49801.1 - 0.073 12.4 0.5 1.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MobB PF03205.9 EMG49801.1 - 0.08 12.6 4.8 1.6 8.4 0.5 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EMG49801.1 - 0.12 13.2 6.0 7.9 7.3 0.5 3.1 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EMG49801.1 - 0.14 11.9 6.5 0.13 12.0 0.1 3.1 3 0 0 3 3 3 0 Dynamin family cobW PF02492.14 EMG49801.1 - 0.72 9.2 3.2 0.67 9.3 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain HhH-GPD PF00730.20 EMG49802.1 - 3e-19 69.2 0.0 4.8e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EMG49802.1 - 3.9e-06 26.2 0.0 9.3e-06 25.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Fungal_trans PF04082.13 EMG49803.1 - 2.2e-35 121.8 1.0 4.3e-35 120.8 0.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG49803.1 - 1.1e-10 41.2 11.0 1.9e-10 40.4 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.16 EMG49803.1 - 0.026 14.4 1.0 0.026 14.4 0.7 2.3 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 EMG49803.1 - 0.07 12.9 0.9 0.29 11.0 0.6 2.0 1 0 0 1 1 1 0 Basic region leucine zipper Oxysterol_BP PF01237.13 EMG49804.1 - 1.4e-124 415.1 0.0 3e-124 414.0 0.0 1.6 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_2 PF12796.2 EMG49804.1 - 8.8e-19 67.6 0.6 1.7e-12 47.5 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMG49804.1 - 2e-15 56.4 0.6 9.7e-07 28.8 0.0 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EMG49804.1 - 7.6e-15 53.8 0.1 5.8e-06 25.8 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 EMG49804.1 - 1.7e-13 49.3 0.3 2.2e-05 24.2 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EMG49804.1 - 1.6e-12 47.5 0.1 1.5e-08 34.8 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH PF00169.24 EMG49804.1 - 1.3e-09 38.1 1.0 5e-09 36.3 0.1 2.4 2 0 0 2 2 2 1 PH domain PH_8 PF15409.1 EMG49804.1 - 1.2e-07 31.7 0.3 3.3e-07 30.2 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EMG49804.1 - 0.00034 20.8 2.0 0.0008 19.6 0.3 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain CRAL_TRIO PF00650.15 EMG49805.1 - 8.2e-21 74.1 0.0 1.1e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMG49805.1 - 0.001 19.1 0.1 0.0033 17.5 0.1 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Prok_Ub PF14454.1 EMG49805.1 - 0.098 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic Ubiquitin Mannosyl_trans3 PF11051.3 EMG49806.1 - 1.5e-85 286.8 0.2 2.2e-85 286.3 0.1 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 EMG49806.1 - 0.00057 19.2 0.5 0.0011 18.3 0.4 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 MFS_1 PF07690.11 EMG49807.1 - 3.5e-33 114.7 48.2 9.1e-33 113.4 31.0 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG49807.1 - 0.00011 20.9 26.7 0.0002 20.0 10.9 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter Exo_endo_phos PF03372.18 EMG49808.1 - 9.1e-15 55.2 0.1 1.2e-14 54.9 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EMG49808.1 - 2.7e-10 39.9 0.2 0.00019 21.0 0.0 2.4 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase Med15_fungi PF05397.7 EMG49809.1 - 7.3e-41 138.7 1.7 7.3e-41 138.7 1.2 6.5 7 1 0 7 7 7 1 Mediator complex subunit 15 WD40 PF00400.27 EMG49810.1 - 1.2e-74 243.7 22.1 1.6e-09 37.2 0.3 11.7 12 0 0 12 12 12 11 WD domain, G-beta repeat Utp12 PF04003.7 EMG49810.1 - 9.2e-24 83.4 0.7 1.7e-23 82.6 0.5 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EMG49810.1 - 7.6e-06 24.3 1.2 0.36 8.9 0.0 4.5 5 0 0 5 5 5 3 Nucleoporin Nup120/160 PLA2_B PF01735.13 EMG49811.1 - 1.2e-187 624.0 3.5 1.6e-187 623.5 2.4 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain His_Phos_1 PF00300.17 EMG49812.1 - 1.1e-15 58.0 0.0 2e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Exo_endo_phos PF03372.18 EMG49813.1 - 2.9e-21 76.5 0.0 4.4e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EMG49813.1 - 5.3e-20 70.5 14.0 2.5e-12 46.1 3.5 2.9 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMG49813.1 - 8e-12 43.4 13.4 0.0033 17.2 0.1 5.1 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_8 PF13855.1 EMG49813.1 - 8.1e-12 44.7 9.6 3.8e-09 36.1 2.2 2.6 1 1 0 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 EMG49813.1 - 5.6e-06 25.7 9.7 0.16 12.2 0.0 4.5 5 0 0 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 EMG49813.1 - 0.00019 21.1 3.8 0.43 10.8 0.0 4.1 3 0 0 3 3 3 2 Leucine Rich repeat Not3 PF04065.10 EMG49814.1 - 2.4e-83 278.9 29.0 2.4e-83 278.9 20.1 2.4 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EMG49814.1 - 2.2e-26 92.3 2.7 2.2e-26 92.3 1.9 3.0 4 0 0 4 4 4 1 NOT2 / NOT3 / NOT5 family DUF572 PF04502.8 EMG49814.1 - 0.002 17.4 27.4 0.002 17.4 19.0 2.7 2 1 1 3 3 3 1 Family of unknown function (DUF572) Orthopox_F8 PF05886.6 EMG49814.1 - 8.6 6.2 10.7 17 5.3 0.6 3.5 3 0 0 3 3 3 0 Orthopoxvirus F8 protein LMWPc PF01451.16 EMG49815.1 - 5.3e-35 120.7 0.0 6.1e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Opy2 PF09463.5 EMG49816.1 - 1.4e-09 37.8 22.0 2.2e-09 37.2 15.2 1.3 1 0 0 1 1 1 1 Opy2 protein Adeno_E3_CR2 PF02439.10 EMG49816.1 - 0.073 12.6 0.5 0.16 11.5 0.4 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.5 EMG49816.1 - 0.11 11.7 1.3 0.25 10.6 0.9 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Enolase_C PF00113.17 EMG49817.1 - 7.5e-154 511.0 0.1 1.1e-153 510.4 0.1 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EMG49817.1 - 4.7e-56 188.3 0.1 1.1e-55 187.1 0.1 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EMG49817.1 - 0.006 16.5 0.1 0.03 14.3 0.0 2.1 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.6 EMG49817.1 - 0.0085 15.0 0.2 0.02 13.8 0.0 1.7 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Transketolase_N PF00456.16 EMG49818.1 - 5.3e-151 502.1 0.0 1.5e-150 500.6 0.0 1.7 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EMG49818.1 - 4.2e-45 153.4 0.0 8e-45 152.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EMG49818.1 - 4.4e-12 46.0 0.0 1e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 EMG49818.1 - 7.5e-07 28.1 0.1 4.4e-06 25.6 0.1 1.9 2 0 0 2 2 2 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EMG49818.1 - 5e-05 22.3 0.0 0.0099 14.8 0.0 2.5 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 EMG49818.1 - 0.00063 19.3 0.4 0.0099 15.4 0.1 2.8 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Alba PF01918.16 EMG49818.1 - 0.076 12.6 0.0 0.45 10.1 0.0 2.3 2 0 0 2 2 2 0 Alba Pkinase PF00069.20 EMG49819.1 - 5.5e-70 235.4 0.0 8.4e-70 234.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG49819.1 - 5.3e-30 104.3 0.0 7.8e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EMG49819.1 - 7e-11 42.4 3.4 7e-11 42.4 2.4 3.0 3 0 0 3 3 3 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMG49819.1 - 0.00051 19.1 0.0 0.0035 16.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMG49819.1 - 0.1 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMG49819.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF605 PF04652.11 EMG49819.1 - 1.4 8.2 19.8 2.4 7.4 13.8 1.3 1 0 0 1 1 1 0 Vta1 like NuA4 PF09340.5 EMG49821.1 - 3e-24 84.4 1.5 3e-24 84.4 1.0 1.9 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 HTH_16 PF12645.2 EMG49821.1 - 0.091 12.6 0.1 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Secretin_N_2 PF07655.8 EMG49821.1 - 0.29 11.5 11.6 0.063 13.6 5.4 1.8 2 0 0 2 2 2 0 Secretin N-terminal domain SR-25 PF10500.4 EMG49821.1 - 0.4 10.1 13.6 0.63 9.4 9.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CBP4 PF07960.6 EMG49822.1 - 4.5e-48 162.0 2.2 5.1e-48 161.9 1.5 1.0 1 0 0 1 1 1 1 CBP4 PSP1 PF04468.7 EMG49822.1 - 0.57 10.2 3.5 0.28 11.1 0.4 1.9 1 1 1 2 2 2 0 PSP1 C-terminal conserved region DUF3810 PF12725.2 EMG49822.1 - 1.5 7.6 4.0 0.61 8.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Clat_adaptor_s PF01217.15 EMG49823.1 - 3.2e-49 166.2 1.3 3.8e-49 166.0 0.9 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF2183 PF09949.4 EMG49823.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) Aminotran_5 PF00266.14 EMG49824.1 - 9.5e-10 37.7 0.0 1.5e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EMG49824.1 - 0.059 11.6 0.0 0.077 11.2 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Na_Ca_ex PF01699.19 EMG49825.1 - 2.3e-50 169.8 30.9 2.2e-25 88.9 11.1 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein YWFCY PF14293.1 EMG49825.1 - 0.056 13.2 0.4 0.2 11.4 0.3 2.0 1 0 0 1 1 1 0 YWFCY protein DUF1352 PF07086.7 EMG49825.1 - 0.069 12.7 0.4 0.23 11.0 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1352) PGPGW PF09656.5 EMG49825.1 - 3 7.2 9.1 4.2 6.7 0.1 3.8 3 0 0 3 3 3 0 Putative transmembrane protein (PGPGW) 7tm_3 PF00003.17 EMG49825.1 - 3.7 6.8 19.9 0.046 13.0 0.8 3.5 2 1 1 3 3 3 0 7 transmembrane sweet-taste receptor of 3 GCPR Cyclin_N PF00134.18 EMG49826.1 - 6e-14 51.7 0.5 1.2e-13 50.6 0.3 1.6 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EMG49826.1 - 2.2e-13 50.8 0.8 3.4e-13 50.2 0.1 1.6 2 0 0 2 2 2 1 Cyclin Cpn60_TCP1 PF00118.19 EMG49827.1 - 7.7e-146 486.5 16.4 8.7e-146 486.3 11.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1466 PF07326.6 EMG49828.1 - 0.011 14.9 1.0 0.017 14.4 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1466) HMG_box PF00505.14 EMG49828.1 - 0.074 13.3 0.7 0.069 13.4 1.5 4.1 3 2 1 4 4 4 0 HMG (high mobility group) box DUF3106 PF11304.3 EMG49828.1 - 0.14 12.5 14.4 1.6 9.2 1.5 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF3106) HMG_box_2 PF09011.5 EMG49828.1 - 0.18 12.1 0.3 0.18 12.1 0.2 4.8 3 1 1 4 4 4 0 HMG-box domain GAS PF13851.1 EMG49828.1 - 0.27 10.3 10.4 0.5 9.5 7.2 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Tox-URI2 PF15653.1 EMG49828.1 - 1 9.6 9.1 2.2 8.5 0.2 2.7 2 1 1 3 3 3 0 URI fold toxin 2 Fungal_trans_2 PF11951.3 EMG49829.1 - 7.4e-11 41.2 0.4 1.2e-10 40.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG49829.1 - 5e-08 32.7 9.8 5e-08 32.7 6.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GDC-P PF02347.11 EMG49830.1 - 2.9e-194 645.6 0.0 2e-180 600.0 0.0 2.2 2 0 0 2 2 2 2 Glycine cleavage system P-protein Aminotran_5 PF00266.14 EMG49830.1 - 5.6e-06 25.3 0.3 0.0093 14.7 0.0 2.4 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 EMG49830.1 - 0.00027 20.1 0.0 0.00046 19.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_3 PF00202.16 EMG49830.1 - 0.023 13.5 0.0 0.078 11.8 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class-III S-methyl_trans PF02574.11 EMG49831.1 - 3.5e-55 187.4 0.0 3.9e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase PTA_PTB PF01515.14 EMG49831.1 - 0.049 12.6 0.1 0.077 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase MIF4G_like PF09088.6 EMG49832.1 - 4e-76 254.7 3.5 1.2e-75 253.1 2.4 1.9 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 EMG49832.1 - 1.4e-50 171.9 9.7 1.6e-50 171.6 5.1 2.4 2 1 0 2 2 2 1 MIF4G like MIF4G PF02854.14 EMG49832.1 - 1.4e-15 57.2 7.8 1.4e-15 57.2 5.4 3.7 4 1 0 5 5 5 1 MIF4G domain ABC_tran PF00005.22 EMG49833.1 - 2.3e-15 57.0 0.0 6.9e-15 55.5 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EMG49833.1 - 4.2e-11 43.3 3.8 2.8e-09 37.3 0.7 2.6 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 EMG49833.1 - 4e-06 26.2 0.0 0.054 12.7 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EMG49833.1 - 4.6e-06 25.9 0.0 0.028 13.4 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EMG49833.1 - 0.00096 18.6 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EMG49833.1 - 0.0013 19.1 1.0 0.0022 18.3 0.1 1.8 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EMG49833.1 - 0.0029 17.2 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 EMG49833.1 - 0.0038 18.0 1.5 0.02 15.7 1.0 2.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EMG49833.1 - 0.005 16.0 0.1 0.01 15.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 EMG49833.1 - 0.0079 15.6 0.2 0.053 12.9 0.1 1.9 1 1 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 EMG49833.1 - 0.011 16.0 0.0 0.028 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.1 EMG49833.1 - 0.018 13.5 0.0 0.025 13.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EMG49833.1 - 0.022 14.9 0.4 0.18 11.9 0.3 2.1 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EMG49833.1 - 0.025 13.9 0.1 0.33 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Epiglycanin_C PF14654.1 EMG49833.1 - 0.034 14.1 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region AAA PF00004.24 EMG49833.1 - 0.053 13.7 0.0 1.6 8.9 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMG49833.1 - 0.053 13.4 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 EMG49833.1 - 0.06 13.0 0.2 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MutS_V PF00488.16 EMG49833.1 - 0.081 12.3 0.0 0.33 10.3 0.0 1.9 2 0 0 2 2 2 0 MutS domain V AAA_33 PF13671.1 EMG49833.1 - 0.095 12.5 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ras PF00071.17 EMG49835.1 - 2.8e-51 173.0 0.0 3.3e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMG49835.1 - 8.6e-15 55.2 0.0 1.3e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMG49835.1 - 7.7e-07 28.5 0.0 1e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family ABC_tran PF00005.22 EMG49836.1 - 2.1e-09 37.7 0.0 2.4e-09 37.5 0.0 1.0 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EMG49836.1 - 0.032 13.4 0.0 0.032 13.4 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain PTCRA PF15028.1 EMG49837.1 - 2.6 7.5 6.6 14 5.2 0.1 2.2 1 1 1 2 2 2 0 Pre-T-cell antigen receptor Flocculin_t3 PF13928.1 EMG49838.1 - 1.8e-11 44.0 25.6 1.8e-11 44.0 17.8 2.5 2 1 1 3 3 3 1 Flocculin type 3 repeat Mso1_C PF14477.1 EMG49838.1 - 0.069 13.4 3.3 0.17 12.2 2.3 1.7 1 0 0 1 1 1 0 Membrane-polarising domain of Mso1 Cpn60_TCP1 PF00118.19 EMG49839.1 - 2e-131 438.9 12.1 2.4e-131 438.7 8.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Apc9 PF12856.2 EMG49839.1 - 0.023 14.7 0.3 0.066 13.3 0.2 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 Dus PF01207.12 EMG49840.1 - 1.7e-72 243.8 0.0 2.2e-72 243.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Mito_carr PF00153.22 EMG49840.1 - 4e-11 42.4 0.1 8.9e-11 41.3 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial carrier protein PEMT PF04191.8 EMG49840.1 - 0.067 13.2 1.1 0.97 9.5 0.0 2.3 2 0 0 2 2 2 0 Phospholipid methyltransferase Mito_carr PF00153.22 EMG49841.1 - 7.5e-65 214.6 1.6 6.3e-21 73.8 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EMG49841.1 - 2.4e-27 94.8 10.3 1.1e-12 47.8 2.3 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EMG49841.1 - 6.1e-22 75.1 20.1 2.1e-05 23.4 0.3 5.4 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.1 EMG49841.1 - 2.1e-18 64.4 21.1 0.00042 19.9 0.0 5.4 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 EMG49841.1 - 3.4e-17 61.7 9.9 2.1e-05 24.0 0.0 5.0 4 1 1 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.1 EMG49841.1 - 1.4e-12 46.3 16.6 0.00036 19.7 0.0 5.4 5 0 0 5 5 5 4 EF hand SPARC_Ca_bdg PF10591.4 EMG49841.1 - 5.8e-05 23.0 2.4 0.0025 17.8 1.3 3.0 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EMG49841.1 - 0.0012 18.7 0.1 1.1 9.2 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain p25-alpha PF05517.7 EMG49841.1 - 0.004 17.4 4.0 4.3 7.5 0.2 3.4 1 1 2 3 3 3 2 p25-alpha DUF2984 PF11203.3 EMG49841.1 - 0.018 15.1 0.2 0.073 13.1 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2984) EF-hand_like PF09279.6 EMG49841.1 - 0.24 11.4 3.3 21 5.2 0.0 3.3 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like DUF866 PF05907.8 EMG49842.1 - 1.6e-42 144.7 2.1 1.8e-42 144.5 1.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Ribosomal_L44 PF00935.14 EMG49842.1 - 0.028 14.4 1.0 3.7 7.6 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein L44 Lar_restr_allev PF14354.1 EMG49842.1 - 0.1 12.9 0.3 5.8 7.2 0.0 2.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar Mcm10 PF09332.6 EMG49842.1 - 0.31 10.3 2.8 0.42 9.9 1.9 1.1 1 0 0 1 1 1 0 Mcm10 replication factor zf-like PF04071.7 EMG49842.1 - 0.42 10.3 3.1 12 5.7 0.1 2.2 1 1 1 2 2 2 0 Cysteine-rich small domain 4HBT PF03061.17 EMG49843.1 - 5.7e-09 35.9 0.0 9.1e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Zn_clus PF00172.13 EMG49844.1 - 3.8e-06 26.7 10.9 6.5e-06 25.9 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.5 EMG49844.1 - 4.2 7.5 7.6 7.8 6.6 5.2 1.4 1 0 0 1 1 1 0 Opy2 protein Zn_clus PF00172.13 EMG49845.1 - 5.6e-08 32.5 11.4 9.3e-08 31.8 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Coatomer_WDAD PF04053.9 EMG49846.1 - 1.2e-140 469.3 9.6 2e-140 468.5 6.7 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EMG49846.1 - 2.4e-79 266.8 0.0 3.4e-79 266.3 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EMG49846.1 - 1.9e-54 179.7 18.1 1.1e-10 40.9 0.7 8.1 8 0 0 8 8 8 5 WD domain, G-beta repeat Nup160 PF11715.3 EMG49846.1 - 4.8e-06 24.9 7.5 0.016 13.3 0.2 3.8 1 1 3 4 4 4 2 Nucleoporin Nup120/160 eIF2A PF08662.6 EMG49846.1 - 0.052 13.2 1.0 1.2 8.8 0.0 3.2 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A MARVEL PF01284.18 EMG49847.1 - 0.00024 20.9 4.8 0.00049 19.9 3.3 1.5 1 1 0 1 1 1 1 Membrane-associating domain Cullin PF00888.17 EMG49848.1 - 4.3e-145 484.5 26.1 5.4e-145 484.2 18.1 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EMG49848.1 - 2e-22 78.8 1.7 2.4e-21 75.3 0.2 2.9 2 0 0 2 2 2 1 Cullin protein neddylation domain Metallophos PF00149.23 EMG49849.1 - 2.1e-38 131.7 0.0 3.5e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 EMG49849.1 - 3.2e-22 77.9 4.8 4.3e-22 77.5 0.3 2.4 1 1 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EMG49849.1 - 1.7e-17 62.2 8.3 1.5e-07 30.6 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat PPP5 PF08321.7 EMG49849.1 - 5.1e-16 58.4 0.3 3e-13 49.6 0.1 4.0 3 1 0 3 3 3 1 PPP5 TPR repeat region TPR_2 PF07719.12 EMG49849.1 - 2.7e-12 45.5 6.5 5.6e-05 22.7 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMG49849.1 - 3.9e-10 39.0 1.0 0.00048 20.1 0.1 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMG49849.1 - 4.1e-08 33.6 0.1 2.2e-07 31.3 0.0 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMG49849.1 - 1.1e-05 25.6 0.4 3.7e-05 23.9 0.1 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMG49849.1 - 9.1e-05 22.7 0.0 0.089 13.4 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMG49849.1 - 0.00017 21.4 2.3 0.065 13.1 0.1 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMG49849.1 - 0.0096 15.6 4.3 1.8 8.5 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMG49849.1 - 0.013 15.3 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMG49849.1 - 0.026 14.2 0.9 4 7.4 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMG49849.1 - 0.068 13.6 0.4 26 5.5 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Med7 PF05983.6 EMG49850.1 - 3.2e-70 235.0 1.7 4.4e-70 234.6 1.2 1.2 1 0 0 1 1 1 1 MED7 protein CBM_20 PF00686.14 EMG49850.1 - 0.22 11.1 1.2 19 4.9 0.0 2.2 2 0 0 2 2 2 0 Starch binding domain CaM_binding PF07839.6 EMG49850.1 - 0.39 10.9 6.2 0.055 13.6 1.5 1.6 2 0 0 2 2 2 0 Plant calmodulin-binding domain RBD-FIP PF09457.5 EMG49850.1 - 1.6 8.6 7.1 0.13 12.0 0.5 2.4 3 0 0 3 3 3 0 FIP domain Adaptin_N PF01602.15 EMG49851.1 - 5.5e-128 427.5 11.9 7.5e-128 427.1 8.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EMG49851.1 - 1.4e-22 80.4 0.5 1.4e-22 80.4 0.3 3.0 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EMG49851.1 - 2.7e-12 46.7 0.2 1.4e-06 28.4 0.0 4.3 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EMG49851.1 - 3.2e-10 39.2 0.2 0.16 12.1 0.0 5.5 4 0 0 4 4 4 3 HEAT repeat Atx10homo_assoc PF09759.4 EMG49851.1 - 0.012 15.3 0.1 3.8 7.2 0.0 3.1 2 1 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.1 EMG49851.1 - 0.012 16.0 0.0 30 5.2 0.0 4.3 3 1 1 4 4 4 0 HEAT-like repeat Metallophos PF00149.23 EMG49852.1 - 5.6e-39 133.6 0.3 8.3e-39 133.0 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WTX PF09422.5 EMG49852.1 - 0.14 11.0 5.9 0.21 10.5 4.1 1.1 1 0 0 1 1 1 0 WTX protein CDK2AP PF09806.4 EMG49852.1 - 0.44 10.7 6.3 0.71 10.0 4.3 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein GAGA_bind PF06217.7 EMG49852.1 - 0.93 9.3 6.8 1.7 8.5 4.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Pex16 PF08610.5 EMG49852.1 - 2.2 7.1 7.2 3.2 6.6 5.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) APC_CDC26 PF10471.4 EMG49852.1 - 3 8.6 18.0 6.5 7.5 12.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Epimerase PF01370.16 EMG49853.1 - 5e-14 52.3 0.1 2.1e-13 50.2 0.1 2.2 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMG49853.1 - 5.5e-13 49.3 0.0 8.3e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMG49853.1 - 4.5e-12 45.7 0.0 6.6e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EMG49853.1 - 8.6e-10 37.7 0.1 2.6e-09 36.1 0.0 1.7 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EMG49853.1 - 9.9e-09 34.4 0.0 2.4e-07 29.9 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain Saccharop_dh PF03435.13 EMG49853.1 - 1.2e-05 24.4 0.0 2.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 EMG49853.1 - 0.00014 20.9 1.7 0.39 9.6 0.1 3.0 1 1 2 3 3 3 2 Male sterility protein DDE_Tnp_1_3 PF13612.1 EMG49853.1 - 0.0077 15.9 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Transposase DDE domain HIM1 PF08732.5 EMG49853.1 - 0.017 13.5 0.0 0.21 9.9 0.0 2.0 2 0 0 2 2 2 0 HIM1 Semialdhyde_dh PF01118.19 EMG49853.1 - 0.07 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain OHCU_decarbox PF09349.5 EMG49854.1 - 3.4e-44 150.9 0.2 3.9e-44 150.7 0.2 1.0 1 0 0 1 1 1 1 OHCU decarboxylase ATP-synt_ab PF00006.20 EMG49855.1 - 1.9e-118 393.5 0.1 2.9e-118 393.0 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Hom_end_hint PF05203.11 EMG49855.1 - 2.2e-67 226.9 0.4 3.2e-67 226.3 0.3 1.2 1 0 0 1 1 1 1 Hom_end-associated Hint Hom_end PF05204.9 EMG49855.1 - 3.1e-39 133.3 3.2 2.8e-33 114.1 0.1 3.1 3 0 0 3 3 3 2 Homing endonuclease ATP-synt_ab_C PF00306.22 EMG49855.1 - 9.5e-19 67.9 0.2 2.4e-18 66.6 0.1 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EMG49855.1 - 1.2e-15 57.4 2.8 3.5e-15 55.9 1.9 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain LAGLIDADG_3 PF14528.1 EMG49855.1 - 1.3e-06 28.5 0.0 0.0014 18.8 0.0 2.7 2 0 0 2 2 2 2 LAGLIDADG-like domain Hint_2 PF13403.1 EMG49855.1 - 8.3e-05 22.5 0.1 0.00031 20.7 0.1 2.0 1 1 0 1 1 1 1 Hint domain Hint PF01079.15 EMG49855.1 - 0.00071 18.8 0.0 0.0017 17.5 0.0 1.6 1 0 0 1 1 1 1 Hint module Mit_KHE1 PF10173.4 EMG49857.1 - 1.7e-52 178.0 3.4 2e-52 177.7 0.3 1.9 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related SKG6 PF08693.5 EMG49857.1 - 0.091 12.0 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MSV199 PF10553.4 EMG49857.1 - 0.24 11.2 5.2 3.6 7.4 0.3 2.4 2 0 0 2 2 2 0 MSV199 domain TerC PF03741.11 EMG49858.1 - 0.14 11.5 0.0 0.15 11.4 0.0 1.0 1 0 0 1 1 1 0 Integral membrane protein TerC family XhlA PF10779.4 EMG49858.1 - 1.3 8.9 5.4 0.41 10.6 0.7 1.9 2 0 0 2 2 2 0 Haemolysin XhlA Pam17 PF08566.5 EMG49859.1 - 3.3e-68 228.7 0.1 3.7e-68 228.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 BPD_transp_2 PF02653.11 EMG49859.1 - 0.00033 19.6 0.5 0.00044 19.3 0.4 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component MFS_1 PF07690.11 EMG49859.1 - 0.0082 14.8 0.9 0.01 14.5 0.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ATPase_gene1 PF09527.5 EMG49859.1 - 0.27 11.0 6.4 5.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) SNF2_N PF00176.18 EMG49860.1 - 2.4e-84 282.6 0.8 2.4e-84 282.6 0.6 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EMG49860.1 - 1.1e-19 70.1 0.1 4.9e-19 68.0 0.0 2.2 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 EMG49860.1 - 2.4e-18 65.7 0.0 1.7e-16 59.8 0.0 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SnAC PF14619.1 EMG49860.1 - 1.4e-13 50.8 4.5 1.4e-13 50.8 3.1 4.4 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex DEAD PF00270.24 EMG49860.1 - 3.1e-07 30.0 1.8 4e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase HSA PF07529.8 EMG49860.1 - 0.015 15.0 17.7 0.019 14.7 5.9 4.0 3 1 0 3 3 3 0 HSA peroxidase PF00141.18 EMG49861.1 - 3.8e-38 131.2 0.0 7.1e-38 130.3 0.0 1.4 1 0 0 1 1 1 1 Peroxidase Ribosomal_L6 PF00347.18 EMG49862.1 - 1.4e-29 102.4 8.6 3.2e-15 56.3 1.6 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 YbbR PF07949.7 EMG49862.1 - 0.034 14.2 2.0 0.47 10.6 1.0 2.7 1 1 0 1 1 1 0 YbbR-like protein DUF2096 PF09869.4 EMG49862.1 - 0.12 12.2 0.8 0.4 10.5 0.5 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) PDT PF00800.13 EMG49863.1 - 2.3e-65 219.5 0.1 2.8e-65 219.2 0.1 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 EMG49863.1 - 0.005 16.2 0.0 0.012 15.0 0.0 1.6 2 0 0 2 2 2 1 ACT domain Histone PF00125.19 EMG49864.1 - 2.1e-26 91.8 0.0 2.5e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMG49864.1 - 3.3e-06 27.0 0.0 4.1e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Coprogen_oxidas PF01218.13 EMG49865.1 - 6.3e-130 432.0 0.0 7.2e-130 431.8 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase UCR_hinge PF02320.11 EMG49866.1 - 2.4e-25 88.2 8.0 3.7e-25 87.6 5.5 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Merozoite_SPAM PF07133.6 EMG49866.1 - 0.029 14.2 12.4 0.04 13.8 8.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DnaG_DnaB_bind PF08278.6 EMG49866.1 - 0.14 12.3 0.3 0.18 12.0 0.2 1.4 1 1 0 1 1 1 0 DNA primase DnaG DnaB-binding Vanabin-2 PF11437.3 EMG49866.1 - 0.17 11.9 2.6 0.25 11.3 1.8 1.2 1 0 0 1 1 1 0 Vanadium-binding protein 2 RRN3 PF05327.6 EMG49866.1 - 0.77 7.7 6.0 0.83 7.6 4.2 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 EBV-NA3 PF05009.7 EMG49866.1 - 0.9 8.7 7.2 1.3 8.2 5.0 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CDC45 PF02724.9 EMG49866.1 - 1.2 7.0 5.6 1.2 7.0 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 EMG49866.1 - 5.4 5.9 11.7 6.3 5.7 8.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.7 EMG49866.1 - 6.4 4.5 14.1 6.8 4.4 9.8 1.1 1 0 0 1 1 1 0 Nop14-like family Actin PF00022.14 EMG49867.1 - 5.5e-13 48.1 0.1 2e-12 46.2 0.1 1.8 1 1 0 1 1 1 1 Actin DsbC_N PF10411.4 EMG49867.1 - 0.015 14.5 3.0 0.031 13.5 0.1 2.7 3 0 0 3 3 3 0 Disulfide bond isomerase protein N-terminus Vps26 PF03643.10 EMG49868.1 - 4.1e-119 396.4 0.1 4.8e-119 396.1 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EMG49868.1 - 1.1e-05 25.3 5.6 0.00018 21.3 0.8 2.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain RasGEF PF00617.14 EMG49869.1 - 5.9e-60 202.2 0.9 1.4e-59 200.9 0.6 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EMG49869.1 - 1.9e-23 82.5 0.8 1e-22 80.1 0.2 2.6 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.23 EMG49869.1 - 1.1e-16 59.8 0.0 3.2e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMG49869.1 - 6.5e-11 41.6 0.1 1.3e-09 37.5 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EMG49869.1 - 2.5e-08 33.2 0.0 1.1e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain Zn_clus PF00172.13 EMG49870.1 - 0.00011 22.0 7.2 0.00022 21.0 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SNF2_N PF00176.18 EMG49871.1 - 4.8e-39 133.9 0.0 2.1e-38 131.8 0.0 2.1 2 1 0 2 2 2 1 SNF2 family N-terminal domain Peptidase_M41 PF01434.13 EMG49872.1 - 4.3e-74 248.5 0.4 6.6e-74 247.9 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EMG49872.1 - 6.6e-42 142.8 0.0 1.5e-41 141.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMG49872.1 - 2.6e-05 25.0 2.8 0.00018 22.3 0.0 3.4 3 1 1 4 4 4 1 AAA domain FtsH_ext PF06480.10 EMG49872.1 - 0.00011 22.3 0.2 0.0005 20.2 0.1 2.1 2 0 0 2 2 2 1 FtsH Extracellular AAA_22 PF13401.1 EMG49872.1 - 0.00017 21.7 0.8 0.17 12.0 0.1 3.0 3 0 0 3 3 3 2 AAA domain TIP49 PF06068.8 EMG49872.1 - 0.0025 16.6 0.8 0.0062 15.2 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus AAA_19 PF13245.1 EMG49872.1 - 0.005 16.5 0.7 0.013 15.2 0.5 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EMG49872.1 - 0.0072 15.3 0.0 0.016 14.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EMG49872.1 - 0.0079 15.6 0.2 0.04 13.3 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.9 EMG49872.1 - 0.013 15.1 1.2 0.039 13.6 0.1 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMG49872.1 - 0.017 15.1 0.0 0.051 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 EMG49872.1 - 0.02 13.9 0.0 0.062 12.3 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_2 PF07724.9 EMG49872.1 - 0.05 13.5 0.0 0.05 13.5 0.0 2.9 4 0 0 4 4 4 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 EMG49872.1 - 0.079 12.3 1.7 0.28 10.5 0.7 2.3 2 1 0 2 2 2 0 AAA domain NYD-SP28 PF14772.1 EMG49872.1 - 0.08 13.0 13.2 0.18 11.9 0.3 2.5 2 0 0 2 2 2 0 Sperm tail AAA_33 PF13671.1 EMG49872.1 - 0.099 12.5 0.7 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Fe-ADH_2 PF13685.1 EMG49872.1 - 0.17 11.1 0.1 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase AAA_11 PF13086.1 EMG49872.1 - 1.5 8.3 7.3 6.7 6.2 0.0 3.0 2 1 0 2 2 2 0 AAA domain Glyco_transf_15 PF01793.11 EMG49874.1 - 7.5e-146 485.2 13.2 9.2e-146 485.0 9.2 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_hydro_3 PF00933.16 EMG49875.1 - 1.9e-78 263.4 0.0 2.8e-78 262.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMG49875.1 - 2e-63 213.9 0.0 1.3e-62 211.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMG49875.1 - 1.3e-24 85.9 1.6 7.8e-24 83.4 1.5 2.1 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 EMG49875.1 - 2.1e-14 53.4 0.6 3.9e-14 52.5 0.4 1.4 1 0 0 1 1 1 1 PA14 domain Lipase_GDSL_2 PF13472.1 EMG49875.1 - 0.066 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Glyco_transf_15 PF01793.11 EMG49876.1 - 4.9e-149 495.7 18.0 6.3e-149 495.4 12.5 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SAP18 PF06487.7 EMG49876.1 - 0.017 14.8 0.0 0.044 13.5 0.0 1.7 1 0 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) Peptidase_C37 PF05416.7 EMG49876.1 - 0.038 12.2 0.5 0.05 11.8 0.4 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DUF1510 PF07423.6 EMG49876.1 - 0.041 13.2 6.8 0.065 12.6 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CENP-H PF05837.7 EMG49876.1 - 0.19 11.9 2.3 0.36 11.0 1.6 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Glyco_hydro_15 PF00723.16 EMG49877.1 - 3.3e-49 167.6 0.0 4.4e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Sec7 PF01369.15 EMG49878.1 - 2.1e-62 210.2 0.7 6.5e-62 208.5 0.5 1.9 1 0 0 1 1 1 1 Sec7 domain PHB_depo_C PF06850.6 EMG49879.1 - 0.045 12.9 0.1 0.058 12.5 0.1 1.2 1 0 0 1 1 1 0 PHB de-polymerase C-terminus DUF2401 PF10287.4 EMG49880.1 - 6.7e-96 320.3 0.6 6.7e-96 320.3 0.4 1.8 2 1 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EMG49880.1 - 3.3e-29 100.8 0.3 7.9e-29 99.6 0.2 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) CHCH PF06747.8 EMG49881.1 - 3.4e-06 26.8 4.4 6.1e-06 26.0 3.1 1.5 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 EMG49881.1 - 0.79 9.5 4.6 1.5 8.6 3.2 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Glyco_hydro_16 PF00722.16 EMG49882.1 - 2.4e-42 144.3 9.6 2.4e-42 144.3 6.7 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 EMG49882.1 - 0.00056 19.8 13.4 0.0011 18.9 9.3 1.4 1 0 0 1 1 1 1 Chitin recognition protein BRO1 PF03097.13 EMG49884.1 - 4.2e-126 420.6 6.6 4.2e-126 420.6 4.6 2.3 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EMG49884.1 - 5e-40 137.2 20.8 1.2e-38 132.7 14.4 2.5 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV Syntaxin-6_N PF09177.6 EMG49884.1 - 0.055 13.8 7.1 0.2 12.0 0.1 3.9 4 0 0 4 4 4 0 Syntaxin 6, N-terminal OMPdecase PF00215.19 EMG49885.1 - 2.5e-77 259.2 0.0 2.9e-77 259.1 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Mito_carr PF00153.22 EMG49886.1 - 1.3e-16 60.0 0.2 1.3e-08 34.4 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF4402 PF14352.1 EMG49888.1 - 0.072 13.5 14.8 0.34 11.3 2.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4402) DUF374 PF04028.8 EMG49888.1 - 0.15 11.3 0.7 2.5 7.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF374) Qn_am_d_aIII PF09099.5 EMG49888.1 - 0.36 11.1 3.6 2.5 8.4 0.3 2.3 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III DUF3415 PF11895.3 EMG49888.1 - 1.7 8.6 4.1 20 5.1 0.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3415) DUF4234 PF14018.1 EMG49889.1 - 0.0069 16.1 6.4 1.3 8.7 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4234) DUF1980 PF09323.5 EMG49889.1 - 0.029 14.1 0.4 0.029 14.1 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF308 PF03729.8 EMG49889.1 - 0.071 13.1 0.2 0.071 13.1 0.2 2.5 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) DUF3611 PF12263.3 EMG49889.1 - 0.085 12.2 0.1 0.085 12.2 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) DUF4448 PF14610.1 EMG49889.1 - 0.086 12.3 0.7 0.55 9.6 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) STE3 PF02076.10 EMG49889.1 - 0.094 11.7 3.6 0.19 10.7 2.5 1.4 1 1 0 1 1 1 0 Pheromone A receptor FtsX PF02687.16 EMG49889.1 - 0.15 11.8 4.3 0.42 10.3 0.6 2.1 2 0 0 2 2 2 0 FtsX-like permease family DUF4064 PF13273.1 EMG49889.1 - 0.51 10.4 6.0 0.41 10.7 1.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4282 PF14110.1 EMG49889.1 - 0.95 9.6 6.9 1.2 9.3 1.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4282) DUF3671 PF12420.3 EMG49889.1 - 1.3 9.0 5.1 0.37 10.7 0.8 1.9 1 1 2 3 3 3 0 Protein of unknown function Rav1p_C PF12234.3 EMG49890.1 - 4.9e-191 636.1 17.7 8.5e-191 635.3 7.8 2.6 3 0 0 3 3 3 2 RAVE protein 1 C terminal WD40 PF00400.27 EMG49890.1 - 3.9e-06 26.5 4.1 1.4 8.8 0.0 6.1 6 1 0 6 6 6 3 WD domain, G-beta repeat E1-E2_ATPase PF00122.15 EMG49891.1 - 3.7e-61 206.0 2.1 3.7e-61 206.0 1.5 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMG49891.1 - 6.5e-44 149.6 7.4 6.5e-44 149.6 5.1 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMG49891.1 - 3.8e-26 92.8 0.0 3.7e-25 89.6 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMG49891.1 - 7.1e-17 61.1 0.0 1.5e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EMG49891.1 - 3.3e-13 50.2 0.0 1.3e-12 48.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMG49891.1 - 3.6e-12 45.5 0.0 1e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EMG49891.1 - 7.1e-05 22.5 0.1 0.0011 18.6 0.1 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SNF2_N PF00176.18 EMG49892.1 - 1.1e-71 241.0 2.2 2e-71 240.2 1.6 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMG49892.1 - 2.1e-17 62.7 0.0 1.2e-16 60.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMG49892.1 - 4e-07 29.6 0.1 1.9e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Pro_CA PF00484.14 EMG49893.1 - 1.2e-40 139.0 0.0 1.5e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Lysine_decarbox PF03641.9 EMG49894.1 - 1.7e-38 131.4 0.0 2.2e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase DUF3354 PF11834.3 EMG49894.1 - 0.089 12.4 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3354) Cu_amine_oxidN1 PF07833.6 EMG49895.1 - 0.072 13.4 7.4 3.7 7.9 0.2 3.5 1 1 1 3 3 3 0 Copper amine oxidase N-terminal domain Aldo_ket_red PF00248.16 EMG49897.1 - 1.5e-42 145.3 0.0 2e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family GntR PF00392.16 EMG49897.1 - 0.0067 15.8 0.0 0.49 9.8 0.0 2.7 2 0 0 2 2 2 2 Bacterial regulatory proteins, gntR family Maf1 PF09174.5 EMG49898.1 - 1.8e-29 102.8 15.1 8.8e-21 74.5 0.5 3.6 3 1 0 3 3 3 2 Maf1 regulator Rtt106 PF08512.7 EMG49898.1 - 0.0024 17.7 0.2 0.01 15.8 0.1 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like UPF0147 PF03685.8 EMG49898.1 - 0.06 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Rad51 PF08423.6 EMG49899.1 - 4.2e-14 52.0 0.3 2.8e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.1 EMG49899.1 - 7.2e-07 28.8 0.0 0.00021 20.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain KaiC PF06745.8 EMG49899.1 - 1.5e-06 27.4 2.7 0.00012 21.2 0.5 3.0 1 1 1 2 2 2 1 KaiC RecA PF00154.16 EMG49899.1 - 2.5e-05 23.5 0.1 5.8e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 recA bacterial DNA recombination protein ABC_tran PF00005.22 EMG49899.1 - 0.00055 20.2 0.1 0.0014 18.9 0.1 1.8 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EMG49899.1 - 0.0051 16.9 0.1 0.016 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EMG49899.1 - 0.023 14.5 0.9 0.27 11.1 0.4 2.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EMG49899.1 - 0.027 14.1 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DnaB_C PF03796.10 EMG49899.1 - 0.04 12.7 1.0 3.3 6.5 0.0 2.8 2 1 1 3 3 3 0 DnaB-like helicase C terminal domain RNA_helicase PF00910.17 EMG49899.1 - 0.043 13.9 0.0 0.16 12.1 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 EMG49899.1 - 0.073 13.8 0.0 0.82 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EMG49899.1 - 0.085 12.3 0.0 0.25 10.8 0.0 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.1 EMG49899.1 - 0.1 12.4 0.0 0.36 10.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain LRR_4 PF12799.2 EMG49900.1 - 3.8e-08 32.7 29.2 0.0011 18.5 0.0 8.3 5 2 4 9 9 9 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG49900.1 - 1.7e-06 27.6 17.0 0.01 15.5 0.1 7.0 6 1 1 7 7 7 3 Leucine rich repeat LRR_7 PF13504.1 EMG49900.1 - 4.1e-06 26.1 6.3 2.9 8.4 0.1 9.5 11 0 0 11 11 11 1 Leucine rich repeat LRR_1 PF00560.28 EMG49900.1 - 0.0002 20.9 15.0 0.042 13.8 0.4 8.4 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_2 PF07723.8 EMG49900.1 - 4.9 7.8 8.8 15 6.3 0.0 5.2 6 0 0 6 6 6 0 Leucine Rich Repeat Fungal_trans PF04082.13 EMG49901.1 - 1.6e-09 37.0 0.9 1.6e-09 37.0 0.6 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pyridoxal_deC PF00282.14 EMG49902.1 - 2.3e-72 243.5 0.0 3.3e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EMG49902.1 - 1.1e-07 31.3 0.0 1.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EMG49902.1 - 0.00012 20.9 0.0 0.00034 19.4 0.0 1.7 2 1 0 2 2 2 1 Aminotransferase class-V MFS_1 PF07690.11 EMG49903.1 - 2.6e-16 59.3 34.3 3.9e-16 58.7 23.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EMG49903.1 - 2.5e-10 40.0 15.5 2.6e-10 40.0 6.2 3.1 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 DUF4164 PF13747.1 EMG49903.1 - 0.19 11.8 8.2 1.6 8.9 0.3 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4164) FlaC_arch PF05377.6 EMG49903.1 - 2.9 7.8 15.0 0.34 10.8 3.5 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4149 PF13664.1 EMG49903.1 - 3.6 7.7 18.7 38 4.4 5.9 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) ABC_tran PF00005.22 EMG49904.1 - 1.2e-47 161.6 0.4 2.2e-22 79.8 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 EMG49904.1 - 2.5e-21 75.3 0.6 2.5e-21 75.3 0.4 3.3 4 0 0 4 4 1 1 ABC transporter AAA_21 PF13304.1 EMG49904.1 - 9.6e-20 71.7 0.1 8e-05 22.7 0.0 4.3 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EMG49904.1 - 2e-10 40.2 0.7 0.027 13.7 0.1 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EMG49904.1 - 1.1e-08 34.4 0.0 0.00082 18.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EMG49904.1 - 3.4e-07 30.4 0.0 0.04 14.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EMG49904.1 - 4.2e-07 30.1 3.1 0.0077 16.2 0.1 3.3 3 2 0 3 3 2 2 AAA ATPase domain AAA_17 PF13207.1 EMG49904.1 - 1.2e-06 29.3 0.1 0.032 15.0 0.0 3.2 3 0 0 3 3 2 2 AAA domain NACHT PF05729.7 EMG49904.1 - 5.4e-06 26.1 0.1 0.12 11.9 0.0 2.7 2 0 0 2 2 2 2 NACHT domain Miro PF08477.8 EMG49904.1 - 1.1e-05 25.8 0.9 0.05 14.1 0.0 3.3 3 0 0 3 3 3 2 Miro-like protein DUF258 PF03193.11 EMG49904.1 - 2e-05 23.8 0.0 0.022 13.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EMG49904.1 - 2.9e-05 24.5 19.5 0.044 14.1 0.0 4.3 4 0 0 4 4 3 2 AAA domain RNA_helicase PF00910.17 EMG49904.1 - 3.7e-05 23.8 0.0 0.17 12.0 0.0 2.9 2 0 0 2 2 2 2 RNA helicase NB-ARC PF00931.17 EMG49904.1 - 6.6e-05 21.9 0.0 0.098 11.4 0.0 2.7 2 1 0 2 2 2 2 NB-ARC domain AAA_5 PF07728.9 EMG49904.1 - 0.0001 22.0 0.0 0.47 10.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EMG49904.1 - 0.00012 21.6 0.2 0.47 9.8 0.0 3.2 3 0 0 3 3 3 1 AAA-like domain AAA_14 PF13173.1 EMG49904.1 - 0.00012 21.9 0.0 0.44 10.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA PF00004.24 EMG49904.1 - 0.00016 21.8 0.0 0.2 11.8 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EMG49904.1 - 0.00021 21.6 0.1 0.28 11.5 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 EMG49904.1 - 0.00042 19.7 0.0 1.9 7.8 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.1 EMG49904.1 - 0.00045 20.2 1.1 0.6 10.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain Arch_ATPase PF01637.13 EMG49904.1 - 0.00099 18.8 5.8 0.14 11.8 0.0 3.7 4 0 0 4 4 4 1 Archaeal ATPase AAA_33 PF13671.1 EMG49904.1 - 0.0012 18.7 0.0 1.5 8.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EMG49904.1 - 0.0019 17.8 2.7 0.1 12.3 0.0 3.1 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B MCM PF00493.18 EMG49904.1 - 0.0025 16.6 1.2 2 7.1 0.0 3.1 3 0 0 3 3 3 1 MCM2/3/5 family MMR_HSR1 PF01926.18 EMG49904.1 - 0.0038 17.1 2.2 3.2 7.7 0.0 3.5 4 2 1 5 5 3 2 50S ribosome-binding GTPase AAA_15 PF13175.1 EMG49904.1 - 0.0085 15.1 5.7 0.5 9.3 0.0 3.5 4 1 1 5 5 5 2 AAA ATPase domain SbcCD_C PF13558.1 EMG49904.1 - 0.01 15.7 0.5 0.39 10.6 0.1 3.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.4 EMG49904.1 - 0.019 14.4 0.4 6.8 6.1 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 EMG49904.1 - 0.027 13.3 3.0 4.6 6.1 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 EMG49904.1 - 0.028 14.0 0.0 1.7 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EMG49904.1 - 0.029 13.5 0.0 0.3 10.2 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 EMG49904.1 - 0.03 14.0 0.1 3.7 7.2 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_13 PF13166.1 EMG49904.1 - 0.036 12.5 9.7 8.6 4.6 0.0 4.0 4 0 0 4 4 4 0 AAA domain ATP-synt_ab PF00006.20 EMG49904.1 - 0.069 12.6 0.0 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.18 EMG49904.1 - 0.07 12.9 4.4 5.2 6.8 0.0 4.4 4 1 0 4 4 4 0 Dynamin family DUF87 PF01935.12 EMG49904.1 - 8.3 6.1 10.5 2.8 7.6 0.0 3.8 4 1 1 5 5 3 0 Domain of unknown function DUF87 DUF3437 PF11919.3 EMG49905.1 - 3.7e-28 97.0 0.0 1.2e-27 95.4 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) Nop14 PF04147.7 EMG49905.1 - 0.11 10.4 6.2 0.24 9.2 4.3 1.5 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 EMG49905.1 - 0.76 9.2 9.6 1.8 8.0 6.6 1.5 1 0 0 1 1 1 0 Nucleoplasmin EF-hand_1 PF00036.27 EMG49906.1 - 1.5e-13 48.9 2.7 0.00028 19.9 0.0 4.3 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.1 EMG49906.1 - 1.3e-12 46.4 1.1 0.00014 21.0 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EMG49906.1 - 3.2e-11 42.1 9.3 0.0002 20.9 0.0 4.6 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.1 EMG49906.1 - 1.5e-10 41.0 6.1 4.3e-05 23.5 0.3 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EMG49906.1 - 0.00014 21.4 2.0 0.14 11.7 0.0 3.6 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_10 PF14788.1 EMG49906.1 - 0.44 10.2 3.7 17 5.1 0.1 3.3 3 1 1 4 4 4 0 EF hand TFIIA PF03153.8 EMG49906.1 - 1.2 8.9 40.6 1.5 8.6 28.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit S10_plectin PF03501.10 EMG49907.1 - 3.7e-37 126.0 0.1 4.3e-37 125.8 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain PadR PF03551.9 EMG49907.1 - 0.07 12.8 0.2 0.15 11.8 0.1 1.7 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family MFS_1 PF07690.11 EMG49908.1 - 3.4e-07 29.3 54.4 1.5e-06 27.1 36.8 3.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG49908.1 - 0.0011 17.6 15.6 0.0011 17.6 10.8 2.9 4 0 0 4 4 4 2 Sugar (and other) transporter Mito_carr PF00153.22 EMG49909.1 - 3.1e-66 219.1 2.2 2.3e-23 81.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M1 PF01433.15 EMG49910.1 - 4e-121 404.7 0.2 6.7e-120 400.7 0.0 2.3 3 0 0 3 3 3 1 Peptidase family M1 ERAP1_C PF11838.3 EMG49910.1 - 3.1e-42 144.9 0.1 4.5e-42 144.4 0.1 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EMG49910.1 - 1.1e-16 60.9 0.0 2.3e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily DUF1360 PF07098.6 EMG49910.1 - 0.0086 15.7 0.1 6.9 6.4 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1360) DUF2265 PF10023.4 EMG49910.1 - 0.016 14.3 0.1 0.029 13.5 0.1 1.3 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) Gag_p10 PF02337.12 EMG49910.1 - 0.083 12.6 0.2 8.2 6.2 0.0 3.0 3 0 0 3 3 3 0 Retroviral GAG p10 protein Pribosyl_synth PF14572.1 EMG49912.1 - 8.2e-40 136.5 1.9 1.4e-39 135.7 1.3 1.4 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EMG49912.1 - 1.4e-31 108.5 0.4 9.1e-31 105.9 0.0 2.5 3 1 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EMG49912.1 - 1.8e-12 47.0 0.2 6.6e-12 45.2 0.1 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EMG49912.1 - 0.071 12.3 0.2 0.13 11.4 0.1 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase ELFV_dehydrog PF00208.16 EMG49914.1 - 2e-63 214.2 0.0 3e-63 213.6 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EMG49914.1 - 9.8e-21 73.0 0.0 1.2e-15 56.1 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EMG49914.1 - 4.7e-05 22.9 0.0 0.0023 17.5 0.0 3.0 3 0 0 3 3 3 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DWNN PF08783.6 EMG49915.1 - 0.043 13.7 2.1 0.86 9.5 0.0 3.1 3 0 0 3 3 3 0 DWNN domain Rpp20 PF12328.3 EMG49915.1 - 0.49 10.0 3.8 1 8.9 2.6 1.6 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P WH2 PF02205.15 EMG49916.1 - 2.6e-13 49.0 0.0 2.9e-10 39.4 0.1 2.9 2 0 0 2 2 2 2 WH2 motif Asn_synthase PF00733.16 EMG49919.1 - 1.9e-46 158.6 0.0 2.8e-46 158.0 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EMG49919.1 - 8.1e-11 41.7 0.0 4.5e-10 39.3 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EMG49919.1 - 6.3e-07 29.4 0.0 2.3e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase domain FlxA PF14282.1 EMG49919.1 - 0.0083 16.0 4.9 0.02 14.7 3.4 1.6 1 0 0 1 1 1 1 FlxA-like protein PHD PF00628.24 EMG49920.1 - 5.7e-06 25.9 7.0 1.4e-05 24.6 4.9 1.7 1 0 0 1 1 1 1 PHD-finger Ecl1 PF12855.2 EMG49920.1 - 0.025 13.8 3.1 0.09 12.0 0.0 2.7 3 0 0 3 3 3 0 Life-span regulatory factor Astro_capsid PF03115.9 EMG49920.1 - 0.039 12.2 4.4 0.049 11.8 3.0 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor zf-HC5HC2H PF13771.1 EMG49920.1 - 0.083 13.0 3.9 0.24 11.5 2.7 1.9 1 0 0 1 1 1 0 PHD-like zinc-binding domain GAGA_bind PF06217.7 EMG49920.1 - 0.33 10.8 12.6 0.57 10.0 8.8 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Ndc1_Nup PF09531.5 EMG49920.1 - 1.1 7.5 4.5 1.4 7.2 3.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zip PF02535.17 EMG49921.1 - 2.3e-47 161.5 8.9 2.8e-47 161.2 6.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF805 PF05656.9 EMG49921.1 - 0.038 13.8 2.0 0.14 12.0 0.0 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF805) Zip PF02535.17 EMG49922.1 - 4.2e-27 94.9 0.5 4.6e-27 94.8 0.4 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter RNB PF00773.14 EMG49923.1 - 2.2e-52 178.3 4.2 2.2e-52 178.3 2.9 2.6 2 1 0 2 2 2 1 RNB domain FAA_hydrolase PF01557.13 EMG49924.1 - 3.8e-59 199.7 0.0 4.7e-59 199.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family NAD_binding_6 PF08030.7 EMG49927.1 - 1.5e-26 93.1 0.2 2.3e-26 92.5 0.1 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMG49927.1 - 2.2e-24 85.3 0.0 5.3e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EMG49927.1 - 4.8e-21 75.1 16.9 4.8e-21 75.1 11.7 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component CFEM PF05730.6 EMG49927.1 - 0.017 14.9 3.3 0.037 13.8 2.3 1.5 1 0 0 1 1 1 0 CFEM domain NAD_binding_1 PF00175.16 EMG49927.1 - 0.023 15.2 0.2 2.8 8.5 0.0 2.7 1 1 1 2 2 2 0 Oxidoreductase NAD-binding domain MARVEL PF01284.18 EMG49927.1 - 5 6.9 14.3 1.2e+02 2.5 9.8 2.9 2 1 1 3 3 3 0 Membrane-associating domain T2SM PF04612.7 EMG49928.1 - 0.032 14.0 0.0 0.037 13.8 0.0 1.0 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Methyltransf_31 PF13847.1 EMG49928.1 - 0.042 13.4 0.1 0.051 13.1 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain LRR_8 PF13855.1 EMG49929.1 - 1.8e-05 24.3 12.9 0.00048 19.8 0.4 6.0 6 0 0 6 6 6 2 Leucine rich repeat F-box-like PF12937.2 EMG49929.1 - 0.009 15.7 0.4 0.028 14.1 0.3 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EMG49929.1 - 0.19 11.3 20.6 0.7 9.5 1.2 6.8 6 2 1 7 7 7 0 Leucine Rich repeats (2 copies) FNIP PF05725.7 EMG49929.1 - 1.1 9.3 19.5 1.1 9.3 0.3 7.2 8 0 0 8 8 8 0 FNIP Repeat MCM PF00493.18 EMG49930.1 - 4.5e-134 446.4 0.0 6.5e-134 445.9 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EMG49930.1 - 1.8e-25 89.7 0.9 8.4e-25 87.6 0.2 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EMG49930.1 - 1.2e-07 31.1 0.1 2e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EMG49930.1 - 1.5e-07 31.2 0.0 2.5e-06 27.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Phage_int_SAM_4 PF13495.1 EMG49930.1 - 0.0084 16.4 0.0 0.68 10.2 0.0 2.7 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain AAA_3 PF07726.6 EMG49930.1 - 0.011 15.3 0.0 0.034 13.7 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EMG49930.1 - 0.11 12.0 0.0 0.72 9.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Stb3 PF10330.4 EMG49931.1 - 1.2e-30 105.0 0.0 3e-30 103.7 0.0 1.7 1 0 0 1 1 1 1 Putative Sin3 binding protein RCR PF12273.3 EMG49934.1 - 0.00032 21.2 2.8 0.00065 20.2 2.0 1.6 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Acyltransferase PF01553.16 EMG49935.1 - 5.7e-14 51.6 0.0 1.2e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Asn_synthase PF00733.16 EMG49936.1 - 2.2e-68 230.5 0.0 3e-68 230.0 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EMG49936.1 - 7e-35 119.4 0.0 1.4e-34 118.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EMG49936.1 - 2.8e-28 98.4 0.0 5.9e-28 97.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EMG49936.1 - 1.1e-06 28.0 0.0 2.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EMG49936.1 - 3.4e-05 22.7 0.0 0.097 11.3 0.0 3.0 1 1 2 3 3 3 3 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EMG49936.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 NAD synthase Pmp3 PF01679.12 EMG49937.1 - 1.5e-18 66.1 3.5 2.1e-18 65.7 2.4 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Abhydrolase_6 PF12697.2 EMG49938.1 - 5.6e-15 55.8 0.0 7.1e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMG49938.1 - 1.5e-09 37.8 0.0 4.3e-09 36.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMG49938.1 - 1.4e-06 28.1 0.0 2.1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 EMG49938.1 - 9.7e-05 21.5 0.1 0.00021 20.4 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.8 EMG49938.1 - 0.00012 21.6 0.0 0.00022 20.9 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF2305 PF10230.4 EMG49938.1 - 0.00093 18.6 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_3 PF07859.8 EMG49938.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 EMG49938.1 - 0.013 14.3 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.15 EMG49938.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.3 EMG49938.1 - 0.019 14.8 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Thioesterase PF00975.15 EMG49938.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain MutS_V PF00488.16 EMG49939.1 - 2.6e-79 265.9 0.3 1.3e-78 263.6 0.0 2.1 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 EMG49939.1 - 1.6e-29 103.2 2.9 2.4e-29 102.5 1.3 1.9 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 EMG49939.1 - 4.3e-22 78.2 0.1 1.5e-21 76.5 0.0 2.0 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EMG49939.1 - 1e-09 38.5 1.7 2e-09 37.6 0.1 2.4 2 1 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EMG49939.1 - 5.4e-09 36.0 4.4 3.1e-08 33.6 3.0 2.3 1 0 0 1 1 1 1 MutS family domain IV ATP-sulfurylase PF01747.12 EMG49940.1 - 5.9e-82 274.1 0.0 9.2e-82 273.5 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 EMG49940.1 - 1.8e-51 173.7 0.0 2.9e-51 173.0 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain zf-C2H2 PF00096.21 EMG49941.1 - 1.2e-08 34.7 8.7 0.00055 20.1 0.8 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMG49941.1 - 1.9e-06 27.8 11.0 9.6e-06 25.6 2.1 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMG49941.1 - 0.0032 17.7 12.1 0.081 13.2 1.8 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger MFS_1 PF07690.11 EMG49942.1 - 6.7e-29 100.6 27.0 6.7e-29 100.6 18.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily JAB PF01398.16 EMG49943.1 - 1.6e-05 24.6 0.2 7.9e-05 22.3 0.0 2.1 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease 6PGD PF00393.14 EMG49944.1 - 1.3e-133 444.7 0.0 1.6e-133 444.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EMG49944.1 - 2e-53 180.5 0.0 2.9e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EMG49944.1 - 0.0047 17.3 0.1 0.0091 16.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EMG49944.1 - 0.016 14.3 0.0 0.037 13.1 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_11 PF14833.1 EMG49944.1 - 0.044 13.8 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase ApbA PF02558.11 EMG49944.1 - 0.06 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EMG49944.1 - 0.075 12.6 0.1 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SSF PF00474.12 EMG49945.1 - 1.2e-22 80.1 13.8 1.8e-22 79.5 9.5 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Biotin_lipoyl PF00364.17 EMG49946.1 - 9.4e-20 70.0 0.4 1.8e-19 69.0 0.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EMG49946.1 - 3e-07 29.9 0.0 7.6e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EMG49946.1 - 0.0017 18.0 0.3 0.063 12.9 0.0 3.0 2 1 1 3 3 3 1 Biotin-lipoyl like HlyD_3 PF13437.1 EMG49946.1 - 0.046 14.0 0.5 2.1 8.7 0.0 3.0 2 1 1 3 3 3 0 HlyD family secretion protein Ribosomal_60s PF00428.14 EMG49946.1 - 0.19 12.1 10.5 1.3 9.4 1.5 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Nramp PF01566.13 EMG49947.1 - 7.1e-90 301.3 5.5 1.1e-49 169.1 3.1 2.1 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein DUF2919 PF11143.3 EMG49947.1 - 0.055 13.2 3.3 0.19 11.5 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) SSF PF00474.12 EMG49948.1 - 2.1e-25 89.2 26.7 3.5e-25 88.5 18.5 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family AT_hook PF02178.14 EMG49950.1 - 0.18 11.5 13.5 0.31 10.8 2.1 2.6 2 0 0 2 2 2 0 AT hook motif SSF PF00474.12 EMG49951.1 - 2.6e-25 88.9 24.3 3.4e-25 88.5 16.8 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Response_reg PF00072.19 EMG49952.1 - 1.5e-19 70.0 0.0 5.6e-13 48.8 0.0 2.4 1 1 1 2 2 2 2 Response regulator receiver domain SUN PF03856.8 EMG49954.1 - 1.7e-100 335.4 19.5 2.3e-100 335.0 13.5 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF3145 PF11343.3 EMG49954.1 - 0.096 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) zf-MYND PF01753.13 EMG49954.1 - 0.13 12.1 2.2 0.31 10.9 1.5 1.5 1 0 0 1 1 1 0 MYND finger Kinetochor_Ybp2 PF08568.5 EMG49955.1 - 3.2e-151 504.7 21.9 3.9e-151 504.4 15.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin AKAP_110 PF05716.8 EMG49955.1 - 0.031 12.2 0.6 0.15 10.0 0.3 1.9 2 0 0 2 2 2 0 A-kinase anchor protein 110 kDa (AKAP 110) zf-SAP30 PF13866.1 EMG49955.1 - 0.14 11.8 0.3 0.4 10.3 0.2 1.7 1 0 0 1 1 1 0 SAP30 zinc-finger HUN PF08729.5 EMG49956.1 - 1.8e-10 40.5 0.7 1.8e-10 40.5 0.5 2.4 2 0 0 2 2 2 1 HPC2 and ubinuclein domain BCDHK_Adom3 PF10436.4 EMG49957.1 - 9e-42 142.3 0.7 1.5e-41 141.6 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EMG49957.1 - 3.3e-11 42.8 0.0 1.5e-08 34.2 0.0 3.2 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EMG49957.1 - 2.6e-06 27.1 0.0 4.2e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ABC_tran PF00005.22 EMG49958.1 - 1.4e-25 90.1 0.0 4.8e-13 49.5 0.0 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EMG49958.1 - 7.7e-06 26.0 14.7 0.00034 20.6 0.1 3.6 3 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EMG49958.1 - 7.8e-05 22.5 0.0 0.14 12.0 0.0 2.4 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EMG49958.1 - 0.00067 19.8 0.7 0.58 10.3 0.2 3.2 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EMG49958.1 - 0.01 14.9 0.0 0.04 13.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EMG49958.1 - 0.032 13.7 0.0 0.078 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EMG49958.1 - 0.045 13.1 0.2 0.77 9.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 EMG49958.1 - 0.09 13.2 0.0 0.26 11.7 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 EMG49958.1 - 0.55 10.5 7.4 0.31 11.3 1.3 2.7 1 1 1 2 2 2 0 AAA domain BSD PF03909.12 EMG49959.1 - 8.1e-13 47.8 1.5 8.1e-13 47.8 1.0 2.7 3 0 0 3 3 3 1 BSD domain CHD5 PF04420.9 EMG49959.1 - 0.15 11.7 0.1 0.15 11.7 0.0 3.0 2 1 1 3 3 3 0 CHD5-like protein TraC PF07820.7 EMG49959.1 - 0.72 10.0 0.0 0.72 10.0 0.0 3.1 4 0 0 4 4 4 0 TraC-like protein Sod_Fe_N PF00081.17 EMG49959.1 - 1.8 8.9 7.0 1.2 9.4 2.1 2.8 2 1 0 2 2 2 0 Iron/manganese superoxide dismutases, alpha-hairpin domain UPF0118 PF01594.11 EMG49959.1 - 2 7.3 2.9 3.6 6.4 1.9 1.5 1 1 0 1 1 1 0 Domain of unknown function DUF20 IL22 PF14565.1 EMG49959.1 - 2.2 8.3 6.8 0.58 10.2 1.0 2.5 2 2 1 3 3 3 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor OEP PF02321.13 EMG49959.1 - 4.5 6.8 14.7 9 5.8 5.7 3.0 2 1 1 3 3 3 0 Outer membrane efflux protein DUF2089 PF09862.4 EMG49959.1 - 9.2 6.0 10.3 0.35 10.6 1.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2089) UCH PF00443.24 EMG49960.1 - 8.3e-46 156.2 0.4 1e-45 155.9 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMG49960.1 - 1.6e-23 83.5 0.2 1.9e-23 83.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C2H2_2 PF12756.2 EMG49960.1 - 0.43 10.7 3.0 9.5 6.3 0.1 2.7 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EMG49960.1 - 5.1 7.6 6.9 17 6.0 0.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger Aminotran_1_2 PF00155.16 EMG49961.1 - 2.9e-61 207.4 0.0 3.7e-61 207.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EMG49961.1 - 1.3e-05 24.4 0.0 1.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EMG49961.1 - 3.9e-05 22.5 0.0 6e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EMG49961.1 - 0.0053 15.8 0.0 0.019 14.0 0.0 1.8 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pkinase PF00069.20 EMG49962.1 - 8.6e-64 215.1 0.0 1.1e-63 214.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG49962.1 - 4.6e-31 107.8 0.0 6.5e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMG49962.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EMG49962.1 - 0.041 12.8 0.0 0.07 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Macoilin PF09726.4 EMG49962.1 - 0.042 12.1 0.2 0.059 11.6 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Kdo PF06293.9 EMG49962.1 - 0.049 12.7 0.0 0.096 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Katanin_con80 PF13925.1 EMG49962.1 - 0.14 11.9 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 con80 domain of Katanin Rho_GDI PF02115.12 EMG49963.1 - 1.3e-19 70.3 0.1 1.5e-19 70.2 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Memo PF01875.12 EMG49964.1 - 9.7e-71 237.8 0.0 1.1e-70 237.6 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Adaptin_N PF01602.15 EMG49965.1 - 3.8e-100 335.6 11.8 4.8e-100 335.3 8.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EMG49965.1 - 1e-17 64.1 0.3 7e-07 29.4 0.0 6.0 3 1 3 6 6 6 4 HEAT repeats HEAT PF02985.17 EMG49965.1 - 2.7e-12 45.6 0.1 0.0004 20.2 0.0 6.0 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.2 EMG49965.1 - 1.9e-10 40.9 4.6 1.7e-09 37.7 0.7 3.3 2 2 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EMG49965.1 - 6e-08 32.2 0.5 0.029 14.1 0.0 5.0 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EMG49965.1 - 1.4e-06 28.5 0.1 0.22 12.0 0.0 5.5 6 0 0 6 6 6 1 HEAT-like repeat CLASP_N PF12348.3 EMG49965.1 - 0.0047 16.3 0.0 0.18 11.1 0.0 2.4 2 0 0 2 2 2 1 CLASP N terminal DNA_alkylation PF08713.6 EMG49965.1 - 0.0088 15.5 0.0 4.5 6.7 0.0 2.7 2 1 1 3 3 3 2 DNA alkylation repair enzyme Pes-10 PF07149.6 EMG49965.1 - 0.012 14.4 0.9 0.038 12.7 0.2 2.1 3 0 0 3 3 3 0 Pes-10 DUF3361 PF11841.3 EMG49965.1 - 0.033 13.9 0.6 0.14 11.8 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) DEAD PF00270.24 EMG49966.1 - 4.2e-24 84.9 0.0 5.4e-22 78.0 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG49966.1 - 6.6e-14 51.5 0.2 1e-12 47.7 0.1 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 EMG49966.1 - 4.2e-10 40.0 0.2 1.3e-09 38.4 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) AA_permease PF00324.16 EMG49968.1 - 5.3e-115 384.4 47.0 6.6e-115 384.1 32.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG49968.1 - 7.9e-26 90.5 52.3 1.1e-25 90.1 36.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMG49969.1 - 1.1e-114 383.3 46.1 1.4e-114 383.0 32.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG49969.1 - 1.9e-29 102.4 50.2 2.6e-29 102.0 34.8 1.1 1 0 0 1 1 1 1 Amino acid permease Orthoreo_P10 PF07204.6 EMG49969.1 - 0.39 10.4 2.2 1.2 8.8 1.5 1.9 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 HemY_N PF07219.8 EMG49969.1 - 8.9 5.9 6.6 33 4.1 0.0 3.1 3 0 0 3 3 3 0 HemY protein N-terminus FTR1 PF03239.9 EMG49970.1 - 4.2e-63 213.1 0.9 5.5e-63 212.7 0.6 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family PIRT PF15099.1 EMG49970.1 - 0.15 11.3 3.8 0.33 10.1 2.7 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF3487 PF11990.3 EMG49970.1 - 9.6 5.6 6.9 1.4 8.3 2.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) UCH PF00443.24 EMG49971.1 - 8.7e-64 215.2 3.8 1.1e-63 214.8 2.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMG49971.1 - 1.1e-27 97.2 2.6 2.1e-27 96.3 1.8 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase FTR1 PF03239.9 EMG49972.1 - 1.7e-17 63.3 0.6 1.8e-17 63.2 0.4 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF2516 PF10724.4 EMG49972.1 - 0.034 14.1 0.9 0.04 13.9 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2516) FtsX PF02687.16 EMG49972.1 - 7.1 6.4 8.6 1.2 8.9 1.7 1.9 1 1 0 1 1 1 0 FtsX-like permease family CAP PF00188.21 EMG49973.1 - 6e-17 62.2 0.5 6e-17 62.2 0.4 1.9 2 1 0 2 2 2 1 Cysteine-rich secretory protein family PAP1 PF08601.5 EMG49973.1 - 0.62 9.7 29.8 0.96 9.0 20.6 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 DUF605 PF04652.11 EMG49973.1 - 0.92 8.8 29.1 1.1 8.5 20.2 1.1 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 EMG49973.1 - 1.9 8.3 15.2 2.3 8.0 10.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF966 PF06136.8 EMG49973.1 - 2.1 7.6 20.0 2.5 7.4 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) KAR9 PF08580.5 EMG49973.1 - 3.1 5.9 23.0 3.8 5.6 15.9 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Peptidase_S64 PF08192.6 EMG49973.1 - 3.2 5.9 17.8 3.9 5.6 12.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 TATR PF03430.8 EMG49973.1 - 3.7 6.0 9.5 4.4 5.8 6.6 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Macoilin PF09726.4 EMG49973.1 - 4.7 5.3 23.7 6.3 4.9 16.4 1.2 1 0 0 1 1 1 0 Transmembrane protein Mitofilin PF09731.4 EMG49973.1 - 7.9 4.9 12.3 9.7 4.6 8.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF566 PF04484.7 EMG49973.1 - 8.2 5.8 29.3 11 5.3 20.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) FTR1 PF03239.9 EMG49974.1 - 3.6e-59 200.2 0.8 4.3e-59 199.9 0.6 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family Bystin PF05291.6 EMG49974.1 - 0.061 12.2 0.2 0.085 11.7 0.1 1.2 1 0 0 1 1 1 0 Bystin Ras PF00071.17 EMG49975.1 - 1.6e-54 183.6 0.1 2.1e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMG49975.1 - 3.4e-21 75.9 0.0 5.5e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMG49975.1 - 2.4e-17 62.7 0.1 2.7e-17 62.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMG49975.1 - 2.1e-08 33.5 0.0 2.8e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMG49975.1 - 3.3e-06 27.0 0.0 4.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMG49975.1 - 6.8e-05 22.3 0.0 0.00013 21.4 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EMG49975.1 - 0.017 14.3 0.1 0.032 13.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EMG49975.1 - 0.019 14.9 0.0 0.074 13.0 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain G-alpha PF00503.15 EMG49975.1 - 0.023 13.3 0.1 0.54 8.8 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit Arch_ATPase PF01637.13 EMG49975.1 - 0.029 14.0 1.0 0.035 13.8 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase MoaE PF02391.12 EMG49975.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 MoaE protein AAA_22 PF13401.1 EMG49975.1 - 0.14 12.3 0.0 0.71 10.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain Cpn10 PF00166.16 EMG49976.1 - 6.3e-29 99.7 0.1 7.1e-29 99.6 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit BP28CT PF08146.7 EMG49977.1 - 5.3e-45 152.8 1.4 5.3e-45 152.8 1.0 4.8 4 0 0 4 4 4 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EMG49977.1 - 6.6e-18 64.8 0.6 6.6e-18 64.8 0.4 3.7 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 10 HEAT_EZ PF13513.1 EMG49977.1 - 0.038 14.4 0.3 3.8 8.1 0.0 4.3 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.17 EMG49977.1 - 0.48 10.6 2.9 39 4.6 0.1 4.5 4 0 0 4 4 4 0 HEAT repeat DUF3808 PF10300.4 EMG49978.1 - 6.3e-121 404.1 1.1 9.2e-121 403.6 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_9 PF13371.1 EMG49978.1 - 0.036 13.8 0.9 11 5.9 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMG49978.1 - 0.039 13.8 1.9 1.9 8.5 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat UNC-50 PF05216.8 EMG49979.1 - 2.2e-88 295.4 15.4 2.6e-88 295.1 10.6 1.0 1 0 0 1 1 1 1 UNC-50 family Sulfotransfer_1 PF00685.22 EMG49979.1 - 0.12 11.5 0.1 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain Sigma70_ner PF04546.8 EMG49980.1 - 0.1 12.2 8.7 0.16 11.5 6.0 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 EMG49980.1 - 0.92 7.4 7.6 1.5 6.7 5.3 1.3 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.5 EMG49980.1 - 1.6 9.0 10.3 3.1 8.1 7.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain IBR PF01485.16 EMG49981.1 - 6.1e-17 61.2 47.4 1.5e-09 37.5 11.7 4.6 3 1 1 4 4 4 2 IBR domain zf-C3HC4 PF00097.20 EMG49981.1 - 1.2e-06 28.0 47.6 2.5e-06 27.0 5.5 4.9 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMG49981.1 - 1.5e-05 24.8 10.3 1.5e-05 24.8 7.2 4.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMG49981.1 - 0.0002 21.1 8.5 0.0002 21.1 5.9 3.7 2 1 1 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 EMG49981.1 - 0.0021 17.7 10.0 0.0021 17.7 6.9 3.7 3 0 0 3 3 3 2 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMG49981.1 - 0.017 14.9 8.1 0.017 14.9 5.6 4.8 2 1 2 4 4 4 0 zinc finger of C3HC4-type, RING Pam16 PF03656.8 EMG49983.1 - 5.3e-33 113.5 1.0 5.9e-33 113.3 0.7 1.0 1 0 0 1 1 1 1 Pam16 PHD PF00628.24 EMG49984.1 - 3.1e-07 29.9 11.4 6.2e-07 29.0 7.9 1.5 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 EMG49984.1 - 0.0016 18.7 0.0 0.0016 18.7 0.0 4.0 4 1 0 4 4 4 1 SET domain Ribosomal_L4 PF00573.17 EMG49985.1 - 1.2e-44 152.0 1.8 2.2e-44 151.1 1.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EMG49985.1 - 1.2e-29 102.0 2.7 8.7e-29 99.2 1.2 2.4 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain LIP PF03583.9 EMG49987.1 - 4.2e-119 397.0 0.0 5e-119 396.7 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 EMG49987.1 - 8.3e-06 25.6 0.0 2.6e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMG49987.1 - 0.0013 17.9 0.1 0.58 9.3 0.2 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EMG49987.1 - 0.0036 17.1 0.0 0.0074 16.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family STAG PF08514.6 EMG49988.1 - 2.9e-15 56.0 0.7 2.9e-15 56.0 0.5 3.9 4 0 0 4 4 4 1 STAG domain DUF1664 PF07889.7 EMG49988.1 - 3 7.6 24.7 0.07 12.9 0.2 4.6 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) WD40 PF00400.27 EMG49989.1 - 7.2e-32 108.1 3.8 2.1e-10 40.0 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat SWIRM PF04433.12 EMG49990.1 - 6.9e-33 112.6 0.4 5.6e-32 109.7 0.1 2.4 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 EMG49990.1 - 2.6e-06 27.3 0.0 6.6e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMG49990.1 - 0.0028 17.7 0.1 0.014 15.5 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.12 EMG49990.1 - 0.016 14.7 2.6 0.053 13.0 0.3 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type Chordopox_RPO7 PF05864.7 EMG49990.1 - 0.074 13.1 0.1 0.29 11.2 0.0 2.1 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Sigma70_ner PF04546.8 EMG49990.1 - 1.7 8.1 12.9 0.069 12.7 3.8 2.5 2 1 1 3 3 3 0 Sigma-70, non-essential region LIP PF03583.9 EMG49992.1 - 2.4e-123 410.9 0.0 2.9e-123 410.7 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 EMG49992.1 - 1.6e-05 24.7 0.0 4.8e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMG49992.1 - 0.00051 19.9 0.0 0.0012 18.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMG49992.1 - 0.037 13.2 0.2 5.8 6.0 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family RRM_1 PF00076.17 EMG49993.1 - 3.3e-19 68.2 0.2 5.7e-14 51.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG49993.1 - 2e-15 56.4 0.0 9.5e-11 41.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG49993.1 - 1.1e-07 31.6 0.0 1.6e-06 27.8 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMG49993.1 - 0.00026 20.7 0.2 0.43 10.4 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.3 EMG49993.1 - 0.0076 15.9 0.0 0.047 13.4 0.0 2.0 2 0 0 2 2 2 1 Limkain b1 eIF3g PF12353.3 EMG49995.1 - 9.6e-48 161.3 5.3 1.4e-47 160.7 2.7 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EMG49995.1 - 2.9e-16 58.8 0.0 5.3e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG49995.1 - 5.5e-12 45.4 0.0 1.2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG49995.1 - 2.6e-08 33.5 0.0 9.5e-08 31.7 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMG49995.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif LTXXQ PF07813.7 EMG49996.1 - 0.098 13.1 2.4 0.12 12.8 1.7 1.1 1 0 0 1 1 1 0 LTXXQ motif family protein Med3 PF11593.3 EMG49996.1 - 2.5 7.2 6.3 2.7 7.1 4.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CBM_48 PF02922.13 EMG49997.1 - 0.0089 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF1168 PF06658.7 EMG49997.1 - 0.015 14.7 5.7 0.03 13.8 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) NARP1 PF12569.3 EMG49997.1 - 0.082 11.6 3.6 0.11 11.2 2.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 zf-H2C2_2 PF13465.1 EMG49998.1 - 9.7e-05 22.4 3.4 9.7e-05 22.4 2.3 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EMG49998.1 - 0.00085 19.5 3.0 0.00085 19.5 2.1 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMG49998.1 - 0.026 14.8 1.0 0.026 14.8 0.7 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.2 EMG49998.1 - 0.027 14.6 1.1 0.027 14.6 0.8 3.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type tRNA_Me_trans PF03054.11 EMG49999.1 - 6.4e-116 386.7 0.0 7.5e-116 386.5 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.12 EMG49999.1 - 0.0013 17.7 0.0 0.0051 15.7 0.0 1.9 2 0 0 2 2 2 1 NAD synthase QueC PF06508.8 EMG49999.1 - 0.1 11.8 0.0 0.28 10.4 0.0 1.7 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ThiI PF02568.9 EMG49999.1 - 0.17 11.3 0.0 0.61 9.5 0.0 1.8 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) FAA_hydrolase PF01557.13 EMG50000.1 - 1.1e-51 175.3 0.0 1.4e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family dCMP_cyt_deam_1 PF00383.17 EMG50001.1 - 2.2e-14 52.9 0.0 3.4e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_18 PF13238.1 EMG50001.1 - 1.4e-08 35.1 0.0 2e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMG50001.1 - 0.00055 20.7 0.0 0.0011 19.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 EMG50001.1 - 0.0046 16.8 0.3 1.4 8.8 0.0 2.5 2 1 0 2 2 2 2 Cytidylate kinase-like family CoaE PF01121.15 EMG50001.1 - 0.018 14.4 0.0 0.041 13.2 0.0 1.6 2 0 0 2 2 2 0 Dephospho-CoA kinase Thymidylate_kin PF02223.12 EMG50001.1 - 0.062 12.6 0.2 0.32 10.3 0.0 2.0 2 1 0 2 2 2 0 Thymidylate kinase Patched PF02460.13 EMG50002.1 - 6.8e-67 226.0 23.5 2.1e-47 161.5 0.6 3.1 3 0 0 3 3 3 3 Patched family Sterol-sensing PF12349.3 EMG50002.1 - 7.9e-46 155.2 6.8 7.9e-46 155.2 4.7 3.1 3 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation Pox_P35 PF03213.9 EMG50002.1 - 0.62 9.0 7.1 0.021 13.8 0.7 1.5 2 0 0 2 2 2 0 Poxvirus P35 protein Epiglycanin_C PF14654.1 EMG50002.1 - 0.63 10.0 4.9 0.84 9.6 0.0 2.6 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Mitofilin PF09731.4 EMG50003.1 - 0.98 7.9 15.2 1.6 7.2 10.6 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PMP1_2 PF08114.6 EMG50003.1 - 2.4 7.7 4.8 4.8 6.7 3.3 1.4 1 0 0 1 1 1 0 ATPase proteolipid family Tetraspannin PF00335.15 EMG50003.1 - 6.7 5.9 10.4 23 4.1 7.2 2.1 1 1 0 1 1 1 0 Tetraspanin family PPI_Ypi1 PF07491.6 EMG50004.1 - 1.7e-24 85.2 17.7 1.7e-24 85.2 12.3 2.1 2 1 0 2 2 2 1 Protein phosphatase inhibitor Pox_P35 PF03213.9 EMG50004.1 - 1.1 8.2 4.0 1.4 7.8 2.8 1.1 1 0 0 1 1 1 0 Poxvirus P35 protein Cwf_Cwc_15 PF04889.7 EMG50004.1 - 3.5 7.2 18.0 5.7 6.5 12.5 1.3 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Apc15p PF05841.6 EMG50004.1 - 8.2 7.1 16.7 2.3 8.9 5.0 2.1 2 0 0 2 2 2 0 Apc15p protein PPR_2 PF13041.1 EMG50005.1 - 0.00022 21.1 0.1 0.0014 18.5 0.0 2.5 2 0 0 2 2 2 1 PPR repeat family Med31 PF05669.7 EMG50005.1 - 0.081 12.6 0.2 0.081 12.6 0.1 3.0 2 1 0 3 3 3 0 SOH1 HATPase_c_3 PF13589.1 EMG50006.1 - 3.5e-14 52.6 0.1 7.8e-14 51.5 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 EMG50006.1 - 5e-14 52.1 0.4 2.8e-13 49.6 0.3 2.1 1 1 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 EMG50006.1 - 2.7e-10 39.9 0.1 8.6e-10 38.3 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_RNApol_7kD PF03604.8 EMG50007.1 - 1.1e-15 56.8 3.0 1.4e-15 56.3 2.1 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 EMG50007.1 - 0.00042 19.9 0.2 0.00046 19.8 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family Prok-RING_1 PF14446.1 EMG50007.1 - 0.0032 17.1 0.8 0.0044 16.7 0.6 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 FYDLN_acid PF09538.5 EMG50007.1 - 0.0071 16.9 0.2 0.0077 16.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) PhnA_Zn_Ribbon PF08274.7 EMG50007.1 - 0.01 15.5 0.4 0.014 15.1 0.3 1.2 1 0 0 1 1 1 0 PhnA Zinc-Ribbon C1_1 PF00130.17 EMG50007.1 - 0.014 15.0 0.9 0.02 14.5 0.6 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 EMG50007.1 - 0.015 15.1 0.9 0.025 14.3 0.6 1.4 1 1 0 1 1 1 0 Double zinc ribbon NCD3G PF07562.9 EMG50007.1 - 0.016 14.8 0.2 0.023 14.4 0.1 1.2 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR ZZ PF00569.12 EMG50007.1 - 0.024 14.1 0.8 4.3 6.9 0.0 2.1 2 0 0 2 2 2 0 Zinc finger, ZZ type DUF2318 PF10080.4 EMG50007.1 - 0.025 14.3 0.2 0.028 14.2 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) TFIIS_C PF01096.13 EMG50007.1 - 0.031 13.9 0.9 1.7 8.3 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) FYVE PF01363.16 EMG50007.1 - 0.039 13.8 1.1 0.048 13.5 0.8 1.2 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.11 EMG50007.1 - 0.065 13.1 0.5 0.069 13.0 0.3 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger Zn-ribbon_8 PF09723.5 EMG50007.1 - 0.07 13.1 3.8 0.23 11.4 2.6 1.8 1 1 0 1 1 1 0 Zinc ribbon domain zf-trcl PF13451.1 EMG50007.1 - 0.11 12.1 1.3 0.64 9.7 0.0 2.1 1 1 1 2 2 2 0 Probable zinc-binding domain zf-C3HC PF07967.8 EMG50007.1 - 0.12 12.0 0.5 0.15 11.7 0.4 1.3 1 1 0 1 1 1 0 C3HC zinc finger-like CpXC PF14353.1 EMG50007.1 - 0.26 11.2 1.9 12 5.8 0.1 2.1 1 1 1 2 2 2 0 CpXC protein zf-dskA_traR PF01258.12 EMG50007.1 - 0.27 11.0 2.8 0.38 10.5 1.5 1.6 1 1 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger RRN7 PF11781.3 EMG50007.1 - 0.28 10.7 4.3 1.6 8.2 0.2 2.3 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 PHD PF00628.24 EMG50007.1 - 0.29 10.8 2.4 2 8.1 2.0 1.9 1 1 1 2 2 2 0 PHD-finger zinc_ribbon_5 PF13719.1 EMG50007.1 - 0.37 10.4 4.5 9.6 5.8 3.2 2.2 1 1 1 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 EMG50007.1 - 0.4 10.5 5.5 6.5 6.6 3.8 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Zn_ribbon_recom PF13408.1 EMG50007.1 - 0.46 10.7 4.3 0.2 11.9 0.7 1.8 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain zinc_ribbon_4 PF13717.1 EMG50007.1 - 0.66 9.7 4.5 11 5.7 3.2 2.2 1 1 1 2 2 2 0 zinc-ribbon domain Tnp_zf-ribbon_2 PF13842.1 EMG50007.1 - 0.76 10.2 4.9 3.4 8.1 3.0 2.1 1 1 1 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Ribosomal_L44 PF00935.14 EMG50007.1 - 0.83 9.7 3.9 11 6.1 0.8 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 Copper-fist PF00649.13 EMG50007.1 - 9.5 5.5 7.3 1.3e+02 1.8 5.0 2.3 1 1 0 1 1 1 0 Copper fist DNA binding domain MFS_1 PF07690.11 EMG50008.1 - 1.3e-41 142.4 48.2 1.6e-40 138.9 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG50008.1 - 1.3e-14 53.6 20.9 2e-14 53.0 14.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EMG50008.1 - 3.6e-05 22.1 2.0 3.6e-05 22.1 1.4 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Acetyltransf_7 PF13508.1 EMG50009.1 - 2.5e-08 33.9 0.0 3.7e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMG50009.1 - 4.9e-08 32.8 0.0 7.9e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EMG50009.1 - 0.0011 18.9 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3245 PF11595.3 EMG50009.1 - 0.0037 17.5 2.0 0.0059 16.9 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3245) Isy1 PF06246.7 EMG50009.1 - 0.0039 16.6 0.1 0.0045 16.4 0.0 1.1 1 0 0 1 1 1 1 Isy1-like splicing family Acetyltransf_10 PF13673.1 EMG50009.1 - 0.0096 16.0 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMG50009.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.1 EMG50009.1 - 0.018 14.9 0.0 6.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain BTV_NS2 PF04514.7 EMG50009.1 - 0.093 11.5 0.8 0.13 11.1 0.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Acetyltransf_4 PF13420.1 EMG50009.1 - 0.12 12.3 0.1 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Tom22 PF04281.8 EMG50009.1 - 0.21 11.0 1.9 0.33 10.4 1.3 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF2731 PF10806.3 EMG50010.1 - 4e-24 85.2 0.0 6.8e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2731) Lipase_GDSL_2 PF13472.1 EMG50010.1 - 0.015 15.4 0.0 0.02 15.0 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family UCH PF00443.24 EMG50011.1 - 3.2e-09 36.2 0.3 5.2e-09 35.5 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EMG50011.1 - 9.6e-09 35.2 0.6 2.1e-08 34.1 0.4 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein JAB PF01398.16 EMG50012.1 - 1e-34 118.6 0.3 1e-34 118.6 0.2 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EMG50012.1 - 5.6e-25 87.6 5.1 1.5e-24 86.3 3.4 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EMG50012.1 - 1.5e-08 34.1 0.0 2.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Peptidase_M24 PF00557.19 EMG50013.1 - 1.1e-54 185.2 0.0 1.4e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EMG50013.1 - 8.4e-25 86.7 0.1 5e-24 84.2 0.0 2.1 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain GDI PF00996.13 EMG50014.1 - 1.9e-198 659.2 0.0 2.2e-198 659.0 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor LRR_4 PF12799.2 EMG50015.1 - 1.1e-12 47.2 36.3 1e-05 24.9 1.6 9.4 5 1 3 9 9 9 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG50015.1 - 9.8e-12 44.4 21.7 4.4e-06 26.3 0.3 6.8 5 2 2 7 7 7 3 Leucine rich repeat FNIP PF05725.7 EMG50015.1 - 4.5e-06 26.5 30.5 0.033 14.1 0.9 7.9 8 0 0 8 8 8 3 FNIP Repeat LRR_7 PF13504.1 EMG50015.1 - 0.00071 19.3 17.6 24 5.6 0.0 10.4 12 1 0 12 12 12 0 Leucine rich repeat LRR_6 PF13516.1 EMG50015.1 - 0.00088 19.1 22.7 4.3 7.7 0.0 9.5 10 1 1 11 11 11 1 Leucine Rich repeat LRR_1 PF00560.28 EMG50015.1 - 0.0041 16.9 29.9 11 6.4 0.2 10.3 9 2 2 11 11 11 1 Leucine Rich Repeat F-box PF00646.28 EMG50015.1 - 0.03 13.9 0.0 0.1 12.2 0.0 2.0 1 0 0 1 1 1 0 F-box domain LRR_4 PF12799.2 EMG50016.1 - 3.7e-12 45.5 40.3 0.00015 21.2 0.1 8.2 7 1 0 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG50016.1 - 5.1e-08 32.5 31.2 4.8e-05 23.0 0.2 7.1 5 2 3 8 8 8 5 Leucine rich repeat LRR_1 PF00560.28 EMG50016.1 - 0.00032 20.3 29.3 0.14 12.2 0.1 10.4 9 2 1 10 10 10 2 Leucine Rich Repeat UPF0728 PF15092.1 EMG50016.1 - 0.07 13.0 0.1 0.52 10.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0728 F-box-like PF12937.2 EMG50016.1 - 0.08 12.6 0.1 0.23 11.1 0.1 1.8 1 0 0 1 1 1 0 F-box-like LRR_7 PF13504.1 EMG50016.1 - 0.39 11.0 35.0 2.8 8.5 0.1 12.3 15 1 0 15 15 15 0 Leucine rich repeat Aldo_ket_red PF00248.16 EMG50017.1 - 1.3e-40 139.0 0.0 1.5e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Asp_protease PF09668.5 EMG50018.1 - 5.6e-32 109.9 0.0 9.3e-32 109.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 EMG50018.1 - 1.2e-10 40.6 0.0 2.7e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family gag-asp_proteas PF13975.1 EMG50018.1 - 5.4e-08 32.5 0.0 9.6e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EMG50018.1 - 3.1e-07 30.8 0.0 6.3e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Rad60-SLD PF11976.3 EMG50018.1 - 4.2e-06 26.3 0.0 1.1e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EMG50018.1 - 0.022 15.0 0.2 0.048 13.9 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain RsmJ PF04378.8 EMG50018.1 - 0.024 13.6 0.4 2.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Ribosomal RNA small subunit methyltransferase D, RsmJ FAM183 PF14886.1 EMG50018.1 - 2.6 8.6 6.3 1.1 9.7 1.4 2.0 2 0 0 2 2 2 0 FAM183A and FAM183B related V_ATPase_I PF01496.14 EMG50018.1 - 4.2 5.0 6.6 5.2 4.7 4.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MFS_1 PF07690.11 EMG50019.1 - 1.7e-39 135.5 29.0 1.7e-39 135.5 20.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG50019.1 - 2.2e-09 36.4 27.3 6.6e-09 34.8 18.5 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EMG50019.1 - 5e-05 21.7 3.0 9.4e-05 20.7 2.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cid2 PF09774.4 EMG50019.1 - 0.087 12.9 0.4 0.15 12.1 0.3 1.3 1 0 0 1 1 1 0 Caffeine-induced death protein 2 DUF2207 PF09972.4 EMG50019.1 - 8.4 4.8 7.9 3.2 6.2 0.0 3.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Amidohydro_1 PF01979.15 EMG50020.1 - 1.9e-07 31.0 0.0 6.7e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EMG50020.1 - 3.4e-06 26.5 0.0 6.8e-05 22.2 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 EMG50020.1 - 2.1e-05 24.2 0.0 6.2e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EMG50020.1 - 4.3e-05 23.6 0.0 0.029 14.4 0.0 2.4 3 0 0 3 3 3 2 Amidohydrolase Glucosamine_iso PF01182.15 EMG50021.1 - 2.1e-19 70.0 0.0 3.3e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hexokinase_1 PF00349.16 EMG50022.1 - 3.9e-22 78.5 0.0 7.1e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EMG50022.1 - 3.9e-21 75.3 0.1 8.9e-20 70.9 0.0 2.2 1 1 0 1 1 1 1 Hexokinase T4_Gp59_C PF08994.5 EMG50022.1 - 0.01 15.9 0.7 0.036 14.2 0.5 2.0 1 1 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term FWWh PF14922.1 EMG50022.1 - 0.011 15.1 0.0 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function RHD3 PF05879.7 EMG50023.1 - 3.1e-267 888.3 19.9 3.7e-267 888.1 13.8 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EMG50023.1 - 4.3e-09 35.8 0.1 8e-09 34.9 0.1 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 EMG50023.1 - 1.3e-06 28.3 0.1 3.4e-06 26.9 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMG50023.1 - 6.4e-05 22.8 0.0 0.00023 21.0 0.0 2.0 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.1 EMG50023.1 - 0.0013 18.6 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EMG50023.1 - 0.0044 17.4 0.0 0.012 16.0 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein ETF_alpha PF00766.14 EMG50024.1 - 7.8e-36 121.5 1.0 1.1e-35 121.0 0.1 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 EMG50024.1 - 3.9e-34 117.7 0.2 6.4e-34 117.0 0.2 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Sulfate_transp PF00916.15 EMG50025.1 - 3.6e-50 170.5 3.9 8.4e-50 169.3 2.7 1.6 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EMG50025.1 - 4.9e-25 87.0 3.7 4.9e-25 87.0 2.6 2.5 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EMG50025.1 - 1e-16 60.3 0.1 2.3e-16 59.2 0.1 1.5 1 0 0 1 1 1 1 STAS domain WD40 PF00400.27 EMG50026.1 - 9.7e-24 82.3 8.2 1.2e-07 31.3 0.0 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EMG50026.1 - 1.5e-23 82.4 0.8 2.7e-23 81.6 0.6 1.4 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 EMG50026.1 - 4.6e-05 23.2 2.7 0.034 13.8 0.3 3.2 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A BING4CT PF08149.6 EMG50026.1 - 0.015 14.7 0.0 10 5.7 0.0 3.5 3 0 0 3 3 3 0 BING4CT (NUC141) domain DUF2415 PF10313.4 EMG50026.1 - 0.06 13.0 0.0 3.7 7.2 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) ATE_C PF04377.10 EMG50029.1 - 7.9e-46 155.2 0.2 2e-45 153.9 0.1 1.7 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EMG50029.1 - 1.6e-21 75.8 2.9 2.1e-20 72.2 2.6 2.2 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Sod_Cu PF00080.15 EMG50030.1 - 6.1e-20 71.8 0.4 1.2e-19 70.9 0.3 1.4 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Mito_carr PF00153.22 EMG50031.1 - 8.2e-62 204.9 0.0 9.2e-23 79.7 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF1279 PF06916.8 EMG50032.1 - 4.6e-33 113.3 0.1 6.9e-33 112.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF3196 PF11428.3 EMG50032.1 - 0.022 14.0 0.1 0.03 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3196) Bac_small_YrzI PF09501.5 EMG50032.1 - 0.92 9.4 4.0 0.28 11.1 0.7 1.7 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) Uricase PF01014.13 EMG50033.1 - 4.7e-58 195.1 6.7 3.4e-37 127.5 1.6 2.3 2 0 0 2 2 2 2 Uricase ThiF PF00899.16 EMG50033.1 - 7.9e-39 132.5 0.0 1.9e-38 131.3 0.0 1.7 1 0 0 1 1 1 1 ThiF family ApbA PF02558.11 EMG50033.1 - 0.0032 16.9 0.5 0.0085 15.5 0.1 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EMG50033.1 - 0.0041 16.5 2.3 0.011 15.1 0.1 2.5 2 1 1 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 EMG50033.1 - 0.0046 17.0 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EMG50033.1 - 0.0096 14.9 0.7 0.031 13.2 0.5 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase NAD_Gly3P_dh_N PF01210.18 EMG50033.1 - 0.013 15.2 0.0 0.037 13.7 0.0 1.8 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EMG50033.1 - 0.014 15.0 0.5 0.12 12.0 0.1 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 EMG50033.1 - 0.025 13.5 0.4 0.044 12.6 0.3 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 EMG50033.1 - 0.026 14.5 0.4 0.093 12.7 0.1 2.1 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_3 PF01494.14 EMG50033.1 - 0.031 13.3 0.2 0.072 12.1 0.1 1.6 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EMG50033.1 - 0.069 13.5 0.1 0.29 11.5 0.1 2.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pex24p PF06398.6 EMG50034.1 - 4.7e-95 318.4 17.1 4.7e-95 318.4 11.8 1.3 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin Prp18 PF02840.10 EMG50035.1 - 5.2e-44 149.5 1.2 5.2e-44 149.5 0.9 2.5 2 2 0 2 2 2 1 Prp18 domain DUF1660 PF07874.6 EMG50035.1 - 0.89 9.8 4.4 22 5.4 0.0 3.4 3 0 0 3 3 3 0 Prophage protein (DUF1660) TFIIF_beta PF02270.10 EMG50036.1 - 2.9e-61 207.7 0.1 3.7e-61 207.3 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Tau95 PF09734.4 EMG50036.1 - 0.027 13.7 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit NDT80_PhoG PF05224.7 EMG50037.1 - 3.7e-60 203.1 0.7 3.7e-60 203.1 0.5 3.8 2 1 1 3 3 3 1 NDT80 / PhoG like DNA-binding family POPLD PF08170.7 EMG50037.1 - 0.0065 16.2 5.5 0.0065 16.2 3.8 4.8 4 1 2 7 7 7 1 POPLD (NUC188) domain Glyco_hydro_76 PF03663.9 EMG50038.1 - 7.7e-30 104.4 13.9 1.1e-29 104.0 9.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EMG50038.1 - 5.8e-07 28.8 1.5 1.1e-06 27.9 0.8 1.7 1 1 1 2 2 2 1 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.8 EMG50038.1 - 1.5e-06 27.6 0.9 0.0012 18.1 0.0 2.5 1 1 1 2 2 2 2 D-glucuronyl C5-epimerase C-terminus Prenyltrans_2 PF13249.1 EMG50038.1 - 0.00011 22.6 4.5 0.0073 16.7 0.2 2.9 1 1 2 3 3 3 2 Prenyltransferase-like DUF1680 PF07944.7 EMG50038.1 - 0.0072 14.6 0.0 0.023 12.9 0.0 1.6 1 1 0 2 2 2 1 Putative glycosyl hydrolase of unknown function (DUF1680) GlcNAc_2-epim PF07221.6 EMG50038.1 - 0.0095 14.9 0.0 1 8.2 0.0 2.9 2 1 2 4 4 4 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Prenyltrans_1 PF13243.1 EMG50038.1 - 0.012 15.6 0.7 0.44 10.5 0.0 2.7 1 1 2 3 3 3 0 Prenyltransferase-like DUF2401 PF10287.4 EMG50039.1 - 1e-90 303.3 4.2 1.6e-90 302.7 2.9 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EMG50039.1 - 3.2e-27 94.4 1.6 9.1e-27 93.0 0.2 2.3 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) AAA_13 PF13166.1 EMG50040.1 - 0.013 13.9 34.1 0.021 13.3 23.6 1.3 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 EMG50040.1 - 0.022 12.1 24.7 0.029 11.7 17.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) bZIP_2 PF07716.10 EMG50040.1 - 0.049 13.4 0.6 0.049 13.4 0.4 4.1 4 1 1 5 5 5 0 Basic region leucine zipper MscS_porin PF12795.2 EMG50040.1 - 0.21 10.8 33.4 0.56 9.4 16.8 2.9 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain IncA PF04156.9 EMG50040.1 - 0.43 10.1 33.0 0.68 9.4 5.6 2.7 1 1 1 2 2 2 0 IncA protein DUF4140 PF13600.1 EMG50040.1 - 1.6 9.2 13.3 24 5.4 0.1 3.9 1 1 3 4 4 4 0 N-terminal domain of unknown function (DUF4140) WEMBL PF05701.6 EMG50040.1 - 1.7 6.9 33.1 0.083 11.3 13.6 1.9 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Mpp10 PF04006.7 EMG50041.1 - 4.6e-106 355.5 70.4 6.1e-106 355.1 48.8 1.1 1 0 0 1 1 1 1 Mpp10 protein Apis_Csd PF11671.3 EMG50041.1 - 4.9 6.9 9.4 21 4.8 6.5 2.0 1 0 0 1 1 1 0 Complementary sex determiner protein SSF PF00474.12 EMG50042.1 - 7.7e-19 67.6 18.8 7.7e-19 67.6 13.0 2.3 2 1 0 2 2 2 1 Sodium:solute symporter family peroxidase PF00141.18 EMG50043.1 - 3.3e-49 167.4 0.0 7.5e-49 166.2 0.0 1.6 2 0 0 2 2 2 1 Peroxidase DUF2424 PF10340.4 EMG50043.1 - 1.8e-26 92.6 2.8 1.4e-25 89.7 1.9 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 EMG50043.1 - 1.7e-16 60.4 0.0 2.9e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMG50043.1 - 0.00023 20.9 0.0 0.00039 20.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family G-patch_2 PF12656.2 EMG50044.1 - 6e-10 38.8 2.9 6.5e-10 38.7 0.1 2.3 2 0 0 2 2 2 1 DExH-box splicing factor binding site Rad17 PF03215.10 EMG50045.1 - 0.0016 17.2 1.0 0.15 10.7 0.0 2.6 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein RRN3 PF05327.6 EMG50046.1 - 1.7e-182 607.4 13.7 3.6e-182 606.4 9.5 1.5 1 1 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 EMG50046.1 - 0.39 8.6 16.3 0.69 7.8 11.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid PF03115.9 EMG50046.1 - 1.6 6.9 6.0 2.3 6.3 4.2 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor RNA_pol_3_Rpc31 PF11705.3 EMG50046.1 - 6.4 6.6 25.9 0.02 14.8 11.2 1.7 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Hyphal_reg_CWP PF11765.3 EMG50047.1 - 5.8e-24 84.4 0.1 1e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Calpain_III PF01067.17 EMG50047.1 - 0.14 11.8 0.3 12 5.5 0.0 2.2 1 1 1 2 2 2 0 Calpain large subunit, domain III Pput2613-deam PF14427.1 EMG50047.1 - 0.18 11.4 1.1 4.2 7.0 0.1 2.5 1 1 2 3 3 3 0 Pput_2613-like deaminase Pput2613-deam PF14427.1 EMG50049.1 - 0.0056 16.3 5.2 0.069 12.8 0.9 2.2 1 1 1 2 2 2 2 Pput_2613-like deaminase DUF4196 PF13846.1 EMG50049.1 - 0.13 12.5 3.1 0.54 10.5 2.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4196) DUF4114 PF13448.1 EMG50049.1 - 1.1 10.1 5.5 18 6.2 3.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4114) DUF3254 PF11630.3 EMG50049.1 - 1.9 8.4 5.4 4.4 7.3 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3254) Podoplanin PF05808.6 EMG50049.1 - 7 6.1 18.0 9.1 5.8 12.5 1.1 1 0 0 1 1 1 0 Podoplanin DUF3254 PF11630.3 EMG50050.1 - 0.094 12.6 3.8 0.29 11.1 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3254) Adeno_E3_CR1 PF02440.10 EMG50050.1 - 0.68 9.4 4.6 7.6 6.1 0.1 3.0 3 0 0 3 3 3 0 Adenovirus E3 region protein CR1 DUF3284 PF11687.3 EMG50050.1 - 1.3 8.7 4.0 0.88 9.3 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3284) DUF4425 PF14466.1 EMG50050.1 - 3.4 7.8 7.4 6.4 6.9 0.5 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4425) NifU PF01106.12 EMG50052.1 - 1.6e-22 79.0 0.1 3.1e-22 78.1 0.0 1.5 2 0 0 2 2 2 1 NifU-like domain Nfu_N PF08712.6 EMG50052.1 - 6.7e-09 35.2 0.0 1.8e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal SRPRB PF09439.5 EMG50053.1 - 5.2e-32 110.5 0.0 6.8e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EMG50053.1 - 2.8e-11 42.9 0.0 4.3e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMG50053.1 - 2e-07 30.9 0.1 2e-07 30.9 0.1 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMG50053.1 - 6e-07 28.8 0.0 7.3e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 EMG50053.1 - 9.4e-06 25.3 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 EMG50053.1 - 3.9e-05 22.9 0.3 9.4e-05 21.7 0.2 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EMG50053.1 - 0.00028 21.3 0.0 0.00049 20.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EMG50053.1 - 0.0024 17.3 0.0 0.0044 16.4 0.0 1.4 1 1 0 1 1 1 1 Ras family EF-hand_2 PF09068.6 EMG50053.1 - 0.0089 16.1 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 EF hand AAA_14 PF13173.1 EMG50053.1 - 0.022 14.6 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EMG50053.1 - 0.065 13.5 0.1 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EMG50053.1 - 0.077 12.4 0.0 0.24 10.8 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Metallophos PF00149.23 EMG50054.1 - 1.5e-44 151.8 0.2 1.8e-44 151.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Vfa1 PF08432.5 EMG50055.1 - 1.9e-47 161.6 0.8 2.9e-47 161.0 0.6 1.3 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 RasGAP_C PF03836.10 EMG50055.1 - 0.15 11.7 5.9 0.26 10.9 4.1 1.3 1 0 0 1 1 1 0 RasGAP C-terminus Bap31 PF05529.7 EMG50055.1 - 0.56 9.6 3.4 0.89 8.9 2.4 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF2663 PF10864.3 EMG50055.1 - 5.3 7.2 6.6 1.6 8.9 2.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) Ribosomal_S27e PF01667.12 EMG50056.1 - 1.5e-29 101.2 6.0 1.9e-29 100.9 4.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EMG50056.1 - 0.00034 20.4 2.7 0.0004 20.2 1.8 1.1 1 0 0 1 1 1 1 IBR domain zf-CSL PF05207.8 EMG50056.1 - 0.097 12.1 1.3 0.17 11.4 0.9 1.5 1 0 0 1 1 1 0 CSL zinc finger DUF3133 PF11331.3 EMG50056.1 - 1.6 8.3 5.7 1.5 8.4 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3133) RRM_1 PF00076.17 EMG50057.1 - 0.00011 21.7 4.5 0.024 14.2 0.2 3.8 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SR-25 PF10500.4 EMG50057.1 - 0.0022 17.4 13.1 0.0022 17.4 9.1 3.7 4 0 0 4 4 4 2 Nuclear RNA-splicing-associated protein RRM_6 PF14259.1 EMG50057.1 - 0.0024 17.7 2.3 1.1 9.2 0.1 3.4 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Spore_coat_CotO PF14153.1 EMG50057.1 - 3.8 6.8 29.2 0.14 11.5 4.6 3.4 3 0 0 3 3 3 0 Spore coat protein CotO TRAP_alpha PF03896.11 EMG50057.1 - 4.3 6.2 25.1 0.41 9.6 1.7 3.1 3 0 0 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit FAD_binding_6 PF00970.19 EMG50058.1 - 2.1e-13 50.1 0.0 3.9e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EMG50058.1 - 1.4e-11 44.8 0.0 4.3e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Globin PF00042.17 EMG50058.1 - 2.2e-09 37.6 0.1 1.1e-08 35.3 0.0 2.2 2 0 0 2 2 2 1 Globin NAD_binding_6 PF08030.7 EMG50058.1 - 0.0057 16.5 0.0 0.0097 15.8 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Protoglobin PF11563.3 EMG50058.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Protoglobin FAD_binding_6 PF00970.19 EMG50059.1 - 8.3e-10 38.6 0.0 1.5e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 EMG50059.1 - 5.7e-08 33.0 0.2 1.1e-07 32.1 0.2 1.5 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.16 EMG50059.1 - 7.3e-08 32.9 0.0 1.5e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EMG50059.1 - 0.03 14.2 0.1 0.091 12.6 0.0 1.8 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Sugar_tr PF00083.19 EMG50060.1 - 3.5e-103 345.5 30.5 4.2e-103 345.3 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG50060.1 - 3e-22 78.8 27.0 3e-22 78.8 18.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily CDC45 PF02724.9 EMG50061.1 - 2e-117 392.8 5.6 2.6e-63 214.0 3.0 2.4 1 1 1 2 2 2 2 CDC45-like protein Nop14 PF04147.7 EMG50061.1 - 0.00016 19.7 2.4 0.00024 19.1 1.7 1.2 1 0 0 1 1 1 1 Nop14-like family Sigma70_ner PF04546.8 EMG50061.1 - 0.21 11.1 8.4 0.1 12.2 3.9 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region Chorismate_synt PF01264.16 EMG50062.1 - 4.8e-134 446.2 0.0 5.6e-134 446.0 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase APH PF01636.18 EMG50063.1 - 2.5e-31 109.2 0.0 3.1e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMG50063.1 - 1.9e-07 30.9 0.2 3.3e-07 30.0 0.2 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EMG50063.1 - 1e-06 28.1 0.1 1.7e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EMG50063.1 - 0.0018 16.9 0.4 0.0034 16.0 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Pkinase PF00069.20 EMG50063.1 - 0.38 9.8 2.2 0.58 9.2 0.3 2.2 3 1 0 3 3 3 0 Protein kinase domain FAD_binding_3 PF01494.14 EMG50064.1 - 2.8e-75 253.5 0.0 5.5e-73 246.0 0.0 2.7 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EMG50064.1 - 7.5e-51 172.0 0.0 1.6e-50 171.0 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.9 EMG50064.1 - 0.012 15.5 0.0 0.029 14.2 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMG50064.1 - 0.02 13.3 0.0 0.031 12.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EMG50064.1 - 0.043 12.9 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DUF2199 PF09965.4 EMG50064.1 - 0.076 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) Trp_halogenase PF04820.9 EMG50064.1 - 0.11 11.1 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 EMG50064.1 - 0.15 10.8 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EMG50064.1 - 0.19 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain DUF1712 PF08217.6 EMG50065.1 - 2.5e-19 68.9 14.5 4.6e-17 61.5 7.9 3.2 1 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) ADH_N PF08240.7 EMG50066.1 - 7.6e-05 22.4 0.1 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain YndJ PF14158.1 EMG50066.1 - 0.18 10.8 0.0 0.25 10.3 0.0 1.1 1 0 0 1 1 1 0 YndJ-like protein FAD_binding_6 PF00970.19 EMG50067.1 - 3.1e-12 46.4 0.0 6.1e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EMG50067.1 - 2.2e-09 37.8 0.0 2e-08 34.7 0.0 2.3 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain Globin PF00042.17 EMG50067.1 - 0.0026 18.0 0.0 0.0053 17.0 0.0 1.6 1 0 0 1 1 1 1 Globin LMBR1 PF04791.11 EMG50070.1 - 1.2e-19 70.2 27.0 2.3e-19 69.3 18.7 1.4 1 1 0 1 1 1 1 LMBR1-like membrane protein PP2C PF00481.16 EMG50071.1 - 5e-44 150.5 0.1 6.1e-38 130.6 0.0 3.0 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EMG50071.1 - 6.1e-06 25.7 0.0 2e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EMG50071.1 - 0.015 15.0 0.1 0.18 11.4 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) DEAD PF00270.24 EMG50072.1 - 1e-37 129.2 0.6 2.4e-37 128.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG50072.1 - 7e-21 73.8 0.4 7e-21 73.8 0.3 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMG50072.1 - 1.6e-07 31.3 0.0 1.6e-07 31.3 0.0 3.0 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EMG50072.1 - 0.00058 18.7 0.2 0.0084 14.9 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain SDA1 PF05285.7 EMG50072.1 - 1.8 7.7 21.0 3.3 6.8 14.5 1.3 1 0 0 1 1 1 0 SDA1 CesA PF11439.3 EMG50073.1 - 0.0022 17.8 0.2 0.0026 17.6 0.2 1.0 1 0 0 1 1 1 1 Type III secretion system filament chaperone CesA Cluap1 PF10234.4 EMG50073.1 - 0.046 12.9 1.2 0.054 12.7 0.8 1.0 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF948 PF06103.6 EMG50073.1 - 0.17 11.7 0.6 0.19 11.5 0.4 1.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Sugar_tr PF00083.19 EMG50074.1 - 6.5e-103 344.7 27.1 7.4e-103 344.5 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG50074.1 - 5.8e-20 71.3 26.2 5.8e-20 71.3 18.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily ASF1_hist_chap PF04729.8 EMG50076.1 - 1.6e-67 225.9 0.1 2.2e-67 225.4 0.1 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Radial_spoke PF04712.7 EMG50076.1 - 0.088 11.5 12.9 0.11 11.2 8.9 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein RNA_pol_Rpc4 PF05132.9 EMG50076.1 - 2.6 8.0 5.9 4 7.4 4.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 VID27 PF08553.5 EMG50076.1 - 4.9 5.2 14.1 5.9 4.9 9.8 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein FAM176 PF14851.1 EMG50076.1 - 6.1 6.5 11.5 12 5.5 8.0 1.6 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.9 EMG50076.1 - 6.9 4.5 13.5 8.6 4.2 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EMG50076.1 - 8.1 4.2 26.3 9.5 3.9 18.2 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 EMG50076.1 - 8.7 5.5 15.6 12 5.0 10.8 1.3 1 0 0 1 1 1 0 NOA36 protein eIF-3c_N PF05470.7 EMG50076.1 - 9.2 4.2 11.4 11 3.9 7.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CobT PF06213.7 EMG50076.1 - 9.9 5.2 22.0 13 4.8 15.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.8 EMG50077.1 - 0.011 15.3 2.4 0.017 14.7 1.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF3530 PF12048.3 EMG50077.1 - 0.072 12.0 1.8 0.1 11.5 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF4613 PF15390.1 EMG50077.1 - 0.076 11.1 1.0 0.1 10.7 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) RICTOR_M PF14666.1 EMG50078.1 - 1.8e-77 259.4 3.5 1.8e-77 259.4 2.4 6.0 8 1 1 9 9 9 2 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_N PF14664.1 EMG50078.1 - 5.7e-75 252.2 15.5 2.8e-74 249.9 10.8 2.1 1 1 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_V PF14668.1 EMG50078.1 - 1.6e-19 69.6 7.4 2.8e-19 68.7 0.1 4.6 6 0 0 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.1 EMG50078.1 - 3.4e-17 62.4 2.2 1.1e-14 54.3 0.1 4.2 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Mem_trans PF03547.13 EMG50079.1 - 4.1e-42 143.8 1.6 5.5e-42 143.4 1.1 1.1 1 0 0 1 1 1 1 Membrane transport protein adh_short PF00106.20 EMG50081.1 - 1.5e-28 99.8 0.1 1.8e-28 99.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMG50081.1 - 4.5e-28 98.6 0.0 5.3e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMG50081.1 - 8.8e-12 45.0 0.0 1.2e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMG50081.1 - 2.9e-05 23.6 0.6 5.7e-05 22.6 0.4 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMG50081.1 - 0.0013 17.5 0.4 0.0018 17.0 0.2 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.13 EMG50081.1 - 0.0027 17.3 0.3 0.0045 16.6 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EMG50081.1 - 0.015 14.2 0.1 0.024 13.6 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF4454 PF14628.1 EMG50081.1 - 0.049 13.2 0.1 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4454) RmlD_sub_bind PF04321.12 EMG50081.1 - 0.087 11.6 0.0 0.19 10.5 0.0 1.6 1 1 1 2 2 2 0 RmlD substrate binding domain DHquinase_II PF01220.14 EMG50081.1 - 0.09 12.1 0.0 1 8.6 0.0 2.1 2 0 0 2 2 2 0 Dehydroquinase class II F420_oxidored PF03807.12 EMG50081.1 - 0.099 13.0 0.3 0.18 12.2 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Zn_clus PF00172.13 EMG50082.1 - 2.6e-07 30.4 7.1 5.5e-07 29.3 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexokinase_2 PF03727.11 EMG50084.1 - 2.6e-70 236.3 0.0 3.7e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EMG50084.1 - 4.9e-65 218.7 0.0 7.5e-65 218.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF1560 PF07597.6 EMG50084.1 - 0.14 12.1 0.6 0.27 11.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1560) FAD_binding_8 PF08022.7 EMG50085.1 - 2e-24 85.4 0.2 5.5e-24 84.0 0.1 1.8 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 EMG50085.1 - 3.6e-24 85.4 0.0 5.4e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMG50085.1 - 1.6e-20 73.4 20.0 1.9e-20 73.1 11.9 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component p450 PF00067.17 EMG50086.1 - 1.9e-63 214.5 0.0 2.6e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SNF2_N PF00176.18 EMG50087.1 - 1.1e-73 247.6 0.0 1.1e-73 247.6 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMG50087.1 - 1.3e-14 53.8 0.0 5.8e-14 51.7 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Flu_M1 PF00598.14 EMG50087.1 - 0.16 11.3 1.3 0.42 9.9 0.9 1.7 1 0 0 1 1 1 0 Influenza Matrix protein (M1) CHZ PF09649.5 EMG50088.1 - 8.7e-21 72.8 1.9 8.7e-21 72.8 1.3 3.6 4 3 0 4 4 4 1 Histone chaperone domain CHZ Cyclin PF08613.6 EMG50089.1 - 5.9e-09 36.4 0.1 1.2e-08 35.5 0.1 1.5 1 0 0 1 1 1 1 Cyclin LSM PF01423.17 EMG50090.1 - 3e-18 65.1 3.3 3.1e-18 65.0 1.5 1.6 1 1 1 2 2 2 1 LSM domain Ras PF00071.17 EMG50091.1 - 7.7e-59 197.6 0.1 9.1e-59 197.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMG50091.1 - 9.8e-21 74.4 0.0 1.5e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMG50091.1 - 5.5e-12 45.2 0.0 7.1e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMG50091.1 - 6.8e-07 29.2 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.1 EMG50091.1 - 0.0019 17.3 1.4 0.012 14.7 1.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMG50091.1 - 0.0021 18.1 0.1 0.016 15.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain GTP_EFTU PF00009.22 EMG50091.1 - 0.0023 17.3 0.0 0.0076 15.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EMG50091.1 - 0.0047 16.1 0.1 0.0082 15.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 KAP_NTPase PF07693.9 EMG50091.1 - 0.0053 15.7 0.0 0.0072 15.3 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain Gtr1_RagA PF04670.7 EMG50091.1 - 0.0057 15.8 0.0 0.01 14.9 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 EMG50091.1 - 0.0072 16.3 0.2 0.017 15.1 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 EMG50091.1 - 0.012 15.9 0.0 0.019 15.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter DUF1128 PF06569.6 EMG50091.1 - 0.016 14.8 0.2 0.037 13.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) AAA_18 PF13238.1 EMG50091.1 - 0.028 14.7 0.0 0.095 13.0 0.0 1.9 1 1 1 2 2 2 0 AAA domain NTPase_1 PF03266.10 EMG50091.1 - 0.039 13.6 0.1 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 NTPase PduV-EutP PF10662.4 EMG50091.1 - 0.056 12.9 0.0 0.11 11.9 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EMG50091.1 - 0.077 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.5 EMG50091.1 - 0.097 11.8 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_32 PF13654.1 EMG50091.1 - 0.12 11.0 0.1 3.6 6.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_21 PF13304.1 EMG50091.1 - 0.53 10.1 4.6 1.6 8.5 3.2 1.8 1 1 0 1 1 1 0 AAA domain TPP_enzyme_N PF02776.13 EMG50093.1 - 2.9e-22 78.9 0.0 4.9e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EMG50093.1 - 1.3e-12 47.5 0.0 4.7e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMG50093.1 - 9.4e-08 31.8 0.0 2.5e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF1242 PF06842.7 EMG50094.1 - 5.6e-18 64.1 1.1 7.4e-18 63.7 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DUF1253 PF06862.7 EMG50095.1 - 2.4e-168 560.1 11.3 2.4e-168 560.1 7.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) P16-Arc PF04699.9 EMG50096.1 - 3e-53 179.9 0.0 3.3e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Methyltransf_28 PF02636.12 EMG50097.1 - 3.7e-81 272.2 0.0 4.9e-81 271.8 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DEP PF00610.16 EMG50098.1 - 6.3e-17 61.0 0.0 1.4e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.18 EMG50098.1 - 2.8e-15 56.2 6.2 1.9e-14 53.6 0.3 3.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 EMG50098.1 - 1.6e-13 50.4 1.0 7.7e-13 48.3 0.7 2.2 1 0 0 1 1 1 1 RhoGAP domain Lectin_leg-like PF03388.8 EMG50099.1 - 3.8e-16 58.8 0.6 6.1e-16 58.2 0.4 1.2 1 0 0 1 1 1 1 Legume-like lectin family Amnionless PF14828.1 EMG50099.1 - 0.00089 17.8 2.2 0.00089 17.8 1.5 1.8 3 0 0 3 3 3 1 Amnionless SF-assemblin PF06705.6 EMG50099.1 - 0.0039 16.3 5.7 0.0039 16.3 3.9 1.8 2 0 0 2 2 2 1 SF-assemblin/beta giardin FlaC_arch PF05377.6 EMG50099.1 - 0.67 9.8 5.2 0.67 9.8 0.4 3.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Spectrin PF00435.16 EMG50099.1 - 0.87 9.8 10.0 0.52 10.6 2.0 2.7 2 1 0 2 2 2 0 Spectrin repeat Cortex-I_coil PF09304.5 EMG50099.1 - 4.2 7.4 11.4 0.22 11.5 2.8 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil WSC PF01822.14 EMG50100.1 - 5.2e-13 48.7 18.1 5.2e-13 48.7 12.5 3.3 2 1 0 2 2 2 1 WSC domain SKG6 PF08693.5 EMG50100.1 - 0.0016 17.7 0.6 0.0016 17.7 0.4 3.9 4 0 0 4 4 4 1 Transmembrane alpha-helix domain Syndecan PF01034.15 EMG50100.1 - 0.018 14.6 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain DUF605 PF04652.11 EMG50100.1 - 9.3 5.5 41.3 0.2 11.0 20.3 2.1 2 0 0 2 2 2 0 Vta1 like EMP24_GP25L PF01105.19 EMG50101.1 - 1.7e-45 154.9 0.2 2e-45 154.7 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF307 PF03733.8 EMG50101.1 - 0.05 14.0 0.3 0.12 12.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF307) NUDE_C PF04880.8 EMG50101.1 - 0.058 13.7 0.0 0.086 13.1 0.0 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region SNF2_N PF00176.18 EMG50102.1 - 5.4e-62 209.2 0.0 1.1e-61 208.2 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMG50102.1 - 8e-15 54.4 0.0 1.8e-13 50.1 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMG50102.1 - 5e-07 29.7 0.0 5e-07 29.7 0.0 3.3 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Peptidase_M1 PF01433.15 EMG50103.1 - 1.4e-67 228.5 7.2 2.1e-67 227.8 5.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EMG50103.1 - 1.6e-59 201.7 0.4 1.6e-59 201.7 0.3 1.7 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EMG50103.1 - 3.1e-12 46.6 0.0 7.3e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily SCFA_trans PF02667.9 EMG50103.1 - 0.023 13.5 0.1 0.037 12.7 0.0 1.3 1 0 0 1 1 1 0 Short chain fatty acid transporter PI3_PI4_kinase PF00454.22 EMG50104.1 - 1.4e-42 145.7 0.3 9.2e-42 143.1 0.0 2.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EMG50104.1 - 1.1e-35 122.6 7.0 1.1e-35 122.6 4.9 2.8 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 EMG50104.1 - 4.6e-12 45.1 0.1 1.4e-11 43.6 0.0 1.9 1 0 0 1 1 1 1 FATC domain RRM_6 PF14259.1 EMG50106.1 - 7.4e-34 115.5 2.5 5.4e-10 39.1 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMG50106.1 - 9.6e-28 95.6 5.6 3.1e-10 39.5 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG50106.1 - 8.5e-21 73.5 3.5 8.2e-07 28.7 0.3 4.8 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMG50106.1 - 0.00038 20.1 0.3 0.9 9.3 0.1 3.6 3 1 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EMG50106.1 - 0.055 13.3 1.0 0.62 9.9 0.1 2.7 3 0 0 3 3 3 0 RNA binding motif Use1 PF09753.4 EMG50107.1 - 6.3e-05 22.5 7.8 0.00014 21.4 5.4 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 Lipoprotein_17 PF04200.7 EMG50107.1 - 8.9 6.5 11.4 1.7 8.8 5.1 2.0 2 0 0 2 2 2 0 Lipoprotein associated domain HD_3 PF13023.1 EMG50108.1 - 0.032 13.9 0.1 0.047 13.4 0.1 1.2 1 0 0 1 1 1 0 HD domain ABC_tran PF00005.22 EMG50110.1 - 1.8e-35 122.2 0.4 4.4e-35 120.9 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 EMG50110.1 - 2.9e-34 118.7 18.2 4.5e-34 118.1 12.6 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EMG50110.1 - 2.1e-09 37.7 2.9 0.011 15.7 0.0 3.8 3 1 1 4 4 3 2 AAA domain SMC_N PF02463.14 EMG50110.1 - 1.1e-07 31.3 1.1 6.1e-05 22.3 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EMG50110.1 - 0.00019 22.2 0.2 0.00049 20.9 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMG50110.1 - 0.00046 20.3 0.3 0.0048 17.0 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EMG50110.1 - 0.00049 19.5 0.1 0.0014 18.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EMG50110.1 - 0.0031 17.5 0.1 0.0088 16.0 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 EMG50110.1 - 0.0064 15.9 0.3 0.019 14.4 0.2 1.7 1 1 0 1 1 1 1 AAA-like domain AAA_14 PF13173.1 EMG50110.1 - 0.011 15.5 0.1 0.2 11.5 0.0 2.6 1 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EMG50110.1 - 0.025 14.4 0.1 0.18 11.7 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 EMG50110.1 - 0.026 13.9 0.0 0.064 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EMG50110.1 - 0.031 13.9 0.0 0.09 12.4 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EMG50110.1 - 0.038 13.8 0.0 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EMG50110.1 - 0.046 13.9 0.0 0.34 11.1 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EMG50110.1 - 0.06 12.9 0.1 0.43 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EMG50110.1 - 0.061 12.5 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 EMG50110.1 - 0.081 12.4 0.1 0.75 9.2 0.1 2.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.1 EMG50110.1 - 0.087 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 EMG50110.1 - 0.11 12.8 2.0 0.15 12.4 0.0 2.3 2 1 1 3 3 2 0 AAA domain Aminotran_5 PF00266.14 EMG50111.1 - 1.2e-28 99.8 0.0 1.5e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 EMG50111.1 - 9e-05 22.3 0.5 0.00051 19.8 0.1 2.3 2 0 0 2 2 2 1 B12 binding domain RCR PF12273.3 EMG50112.1 - 3.8 8.0 10.2 5 7.6 4.0 2.3 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Alba PF01918.16 EMG50113.1 - 1e-10 41.0 0.5 1.8e-10 40.2 0.4 1.4 1 0 0 1 1 1 1 Alba DUF845 PF05820.6 EMG50113.1 - 0.074 12.7 0.3 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF845) Rpp20 PF12328.3 EMG50113.1 - 0.12 12.0 1.9 0.15 11.7 1.3 1.1 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P COX6B PF02297.12 EMG50114.1 - 4.9e-18 64.9 1.5 6.1e-18 64.6 1.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb DUF814 PF05670.8 EMG50115.1 - 1.8e-18 66.2 0.2 4.6e-18 64.8 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF814) TipAS PF07739.8 EMG50115.1 - 0.067 13.5 2.1 0.15 12.3 1.5 1.6 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain CGI-121 PF08617.5 EMG50115.1 - 0.88 9.2 10.1 0.22 11.1 4.0 1.9 2 0 0 2 2 2 0 Kinase binding protein CGI-121 Ribosomal_S2 PF00318.15 EMG50116.1 - 3.9e-57 192.8 0.8 7.1e-57 192.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S2 CS PF04969.11 EMG50117.1 - 1.4e-07 31.9 0.1 2.3e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 CS domain LRR_4 PF12799.2 EMG50118.1 - 2.7e-09 36.4 24.2 0.0042 16.6 0.1 7.9 7 1 2 9 9 9 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG50118.1 - 1.2e-05 24.9 26.4 0.0042 16.8 1.8 6.5 4 2 4 8 8 8 4 Leucine rich repeat LRR_1 PF00560.28 EMG50118.1 - 0.00011 21.7 25.4 0.32 11.1 0.1 8.9 7 2 1 8 8 8 3 Leucine Rich Repeat LRR_7 PF13504.1 EMG50118.1 - 0.0056 16.6 15.3 6.3 7.4 0.0 8.3 8 0 0 8 8 8 2 Leucine rich repeat LRR_6 PF13516.1 EMG50118.1 - 0.73 10.0 0.0 0.73 10.0 0.0 6.7 9 1 1 10 10 10 0 Leucine Rich repeat PALP PF00291.20 EMG50119.1 - 8.6e-57 192.6 0.0 1e-56 192.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PEX11 PF05648.9 EMG50120.1 - 3e-06 26.6 1.7 0.046 12.9 0.0 2.7 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Fumble PF03630.9 EMG50121.1 - 3e-115 384.7 4.0 6.5e-115 383.6 2.8 1.5 1 1 0 1 1 1 1 Fumble Presenilin PF01080.12 EMG50121.1 - 0.84 8.3 3.0 1.3 7.7 2.1 1.2 1 0 0 1 1 1 0 Presenilin NGP1NT PF08153.7 EMG50122.1 - 2.3e-53 179.5 1.1 4.4e-53 178.6 0.8 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EMG50122.1 - 2e-19 69.6 0.0 5.7e-15 55.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EMG50122.1 - 0.00018 20.8 0.0 0.00081 18.6 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EMG50122.1 - 0.00099 18.9 0.5 0.34 10.7 0.0 3.8 3 1 1 4 4 4 1 Dynamin family Arf PF00025.16 EMG50122.1 - 0.002 17.4 0.1 0.13 11.4 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family DUF258 PF03193.11 EMG50122.1 - 0.0037 16.4 0.0 0.0079 15.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EMG50122.1 - 0.0037 16.7 0.0 0.81 9.0 0.0 3.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SusD-like_3 PF14322.1 EMG50122.1 - 0.026 14.6 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Starch-binding associating with outer membrane CAF1 PF04857.15 EMG50123.1 - 2.1e-38 132.1 3.3 2.1e-38 132.1 2.3 2.2 2 1 0 2 2 2 1 CAF1 family ribonuclease Baculo_LEF-11 PF06385.7 EMG50123.1 - 0.012 15.6 0.0 0.064 13.3 0.0 2.2 1 0 0 1 1 1 0 Baculovirus LEF-11 protein CDC50 PF03381.10 EMG50124.1 - 2.3e-99 332.0 4.2 2.7e-99 331.8 2.9 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family tRNA-synt_2c PF01411.14 EMG50125.1 - 8.1e-225 747.3 0.3 1.5e-224 746.3 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EMG50125.1 - 3e-18 65.4 0.2 7.9e-18 64.0 0.1 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF4363 PF14276.1 EMG50125.1 - 0.08 12.6 3.6 0.26 11.0 2.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Oligomerisation PF02410.10 EMG50125.1 - 0.16 11.9 1.8 1.1 9.3 1.2 2.3 1 1 0 1 1 1 0 Oligomerisation domain DUF1992 PF09350.5 EMG50126.1 - 1.2e-19 69.8 0.4 9.8e-19 66.9 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) ORF6N PF10543.4 EMG50126.1 - 0.15 12.0 0.9 5.8 7.0 0.1 2.7 2 1 0 2 2 2 0 ORF6N domain p450 PF00067.17 EMG50127.1 - 6e-64 216.2 0.0 7.4e-64 215.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LisH PF08513.6 EMG50128.1 - 1.1e-06 28.2 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 LisH Glycos_transf_1 PF00534.15 EMG50129.1 - 3e-09 36.5 0.0 5.6e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EMG50129.1 - 4.3e-07 29.8 0.0 1.6e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase Family 4 WD40 PF00400.27 EMG50130.1 - 4.8e-30 102.3 3.1 1.2e-05 25.0 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat CNH PF00780.17 EMG50130.1 - 0.0035 16.8 0.0 0.04 13.3 0.0 2.0 1 1 0 1 1 1 1 CNH domain Voltage_CLC PF00654.15 EMG50131.1 - 1.4e-85 287.4 14.8 1.9e-85 287.0 10.2 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel His_Phos_1 PF00300.17 EMG50132.1 - 1.8e-14 54.1 0.0 3.8e-14 53.0 0.0 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) zf-RAG1 PF10426.4 EMG50132.1 - 0.043 13.7 0.2 0.096 12.6 0.1 1.5 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain DNA_pol_viral_N PF00242.12 EMG50132.1 - 0.081 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain FF PF01846.14 EMG50132.1 - 0.09 12.7 0.4 12 5.9 0.0 3.1 3 0 0 3 3 3 0 FF domain Spc7 PF08317.6 EMG50133.1 - 7.1e-46 156.3 17.6 7.1e-46 156.3 12.2 2.3 2 1 0 2 2 2 1 Spc7 kinetochore protein ACR_tran PF00873.14 EMG50133.1 - 0.32 8.3 1.4 0.5 7.6 1.0 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Aa_trans PF01490.13 EMG50134.1 - 4.9e-98 328.2 25.1 5.6e-98 328.1 17.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TIMELESS PF04821.9 EMG50134.1 - 0.034 13.4 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 Timeless protein Motile_Sperm PF00635.21 EMG50135.1 - 2e-24 85.3 0.0 5.8e-24 83.8 0.0 1.8 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Med15 PF09606.5 EMG50135.1 - 0.051 11.7 41.0 0.067 11.3 28.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 EMG50135.1 - 0.87 7.7 38.0 1.1 7.4 26.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Plasmodium_Vir PF05795.6 EMG50135.1 - 1.6 7.8 7.4 5.6 6.0 1.8 2.1 1 1 1 2 2 2 0 Plasmodium vivax Vir protein DUF1109 PF06532.6 EMG50135.1 - 1.9 7.8 6.1 0.33 10.3 1.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1109) Microtub_assoc PF07989.6 EMG50135.1 - 2.9 7.7 6.1 0.4 10.5 0.2 2.1 2 0 0 2 2 2 0 Microtubule associated Peptidase_M24 PF00557.19 EMG50136.1 - 2.7e-43 147.9 0.4 3.4e-43 147.6 0.3 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 CDC45 PF02724.9 EMG50136.1 - 1.5 6.7 6.3 2.1 6.2 4.4 1.2 1 0 0 1 1 1 0 CDC45-like protein ALG3 PF05208.8 EMG50138.1 - 4e-100 335.6 28.7 5.9e-100 335.0 19.9 1.2 1 0 0 1 1 1 1 ALG3 protein RRM_5 PF13893.1 EMG50138.1 - 1.7e-05 24.5 0.0 3.7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pik1 PF11522.3 EMG50138.1 - 0.6 9.8 3.4 0.71 9.6 0.2 2.5 2 0 0 2 2 2 0 Yeast phosphatidylinositol-4-OH kinase Pik1 zf-C4H2 PF10146.4 EMG50141.1 - 0.042 13.8 0.5 0.065 13.2 0.3 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein DUF2272 PF10030.4 EMG50142.1 - 0.037 13.5 0.0 0.089 12.2 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2272) DUF1289 PF06945.8 EMG50142.1 - 0.53 9.7 11.2 8.4 5.9 0.0 4.7 6 0 0 6 6 6 0 Protein of unknown function (DUF1289) DUF1413 PF07205.6 EMG50142.1 - 2 7.9 9.8 13 5.4 0.1 4.5 5 1 0 5 5 5 0 Domain of unknown function (DUF1413) PEX11 PF05648.9 EMG50143.1 - 1.9e-72 243.1 0.6 2.1e-72 243.0 0.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUSP PF06337.7 EMG50144.1 - 0.047 14.0 0.3 0.047 14.0 0.2 1.5 2 0 0 2 2 2 0 DUSP domain NTF2 PF02136.15 EMG50145.1 - 8.8e-14 51.8 0.4 8.8e-14 51.8 0.3 1.6 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain Daxx PF03344.10 EMG50145.1 - 3.1 6.1 28.0 4.4 5.6 19.4 1.1 1 0 0 1 1 1 0 Daxx Family Spore_II_R PF09551.5 EMG50145.1 - 4.4 7.3 10.0 0.76 9.8 2.9 2.4 1 1 1 2 2 2 0 Stage II sporulation protein R (spore_II_R) UQ_con PF00179.21 EMG50146.1 - 4.3e-44 149.3 0.0 5.3e-44 149.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EMG50146.1 - 8.1e-19 66.9 0.1 1.3e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 EMG50146.1 - 2.8e-06 27.1 0.0 4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMG50146.1 - 0.033 14.0 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 RWD domain UBA_2 PF08587.6 EMG50146.1 - 0.038 14.1 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) DUF4224 PF13986.1 EMG50146.1 - 0.15 11.6 0.0 3.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) Not1 PF04054.10 EMG50147.1 - 9.2e-142 472.3 0.4 2.7e-141 470.8 0.3 1.9 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EMG50147.1 - 8.2e-34 116.4 2.4 8.2e-34 116.4 1.6 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3819) SCA7 PF08313.7 EMG50148.1 - 8.8e-09 34.8 0.0 8.8e-09 34.8 0.0 2.7 3 0 0 3 3 3 1 SCA7, zinc-binding domain DUF4626 PF15422.1 EMG50148.1 - 0.16 11.9 1.1 0.39 10.6 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4626) Rtt102p PF09510.5 EMG50148.1 - 1.1 9.3 5.7 1.4 8.9 0.1 2.5 2 0 0 2 2 2 0 Rtt102p-like transcription regulator protein Hom_end_hint PF05203.11 EMG50148.1 - 3.3 7.3 13.3 2.1 8.0 3.8 2.3 2 1 0 2 2 2 0 Hom_end-associated Hint Pkinase PF00069.20 EMG50149.1 - 7.4e-61 205.5 0.1 1e-60 205.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50149.1 - 2e-37 128.6 0.0 2.6e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG50149.1 - 0.00012 21.1 0.0 0.00079 18.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EMG50149.1 - 0.035 13.4 0.2 0.055 12.8 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 EMG50149.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMG50149.1 - 0.2 11.3 0.0 0.42 10.2 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Radical_SAM PF04055.16 EMG50150.1 - 1.7e-24 86.8 0.0 5.6e-24 85.1 0.0 1.9 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 EMG50150.1 - 4e-22 78.0 0.0 1.3e-21 76.4 0.0 2.0 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 EMG50150.1 - 3.6e-15 56.2 0.0 1.4e-14 54.3 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin Glycos_transf_1 PF00534.15 EMG50152.1 - 3.1e-15 56.0 0.0 6.1e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EMG50152.1 - 0.0013 18.8 0.0 0.0031 17.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Coatomer_WDAD PF04053.9 EMG50153.1 - 1.3e-171 571.3 3.7 1.3e-171 571.3 2.6 1.7 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EMG50153.1 - 4.4e-47 156.3 9.0 5e-10 38.8 0.0 8.1 9 0 0 9 9 9 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 EMG50153.1 - 2.6e-05 23.9 0.3 0.081 12.7 0.0 4.6 3 2 3 6 6 6 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 EMG50153.1 - 0.00023 19.4 2.9 0.023 12.8 0.0 3.9 2 2 2 4 4 4 2 Nucleoporin Nup120/160 NAD_binding_11 PF14833.1 EMG50153.1 - 0.13 12.2 0.0 13 5.8 0.0 2.5 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase FtsJ PF01728.14 EMG50154.1 - 1e-22 81.0 0.0 1.5e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 EMG50154.1 - 0.1 12.2 0.0 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Ribosomal_L1 PF00687.16 EMG50155.1 - 2.8e-46 157.6 4.0 3.4e-46 157.3 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Arf PF00025.16 EMG50156.1 - 1.1e-58 197.2 1.8 1e-55 187.6 0.0 3.6 3 1 0 3 3 3 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMG50156.1 - 9e-24 83.6 0.0 3.2e-14 52.8 0.0 3.7 3 0 0 3 3 3 2 50S ribosome-binding GTPase Miro PF08477.8 EMG50156.1 - 9.5e-12 45.4 0.3 2.1e-06 28.2 0.0 3.6 4 0 0 4 4 4 2 Miro-like protein SRPRB PF09439.5 EMG50156.1 - 1.4e-09 37.3 0.0 2.1e-08 33.6 0.0 2.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EMG50156.1 - 2.8e-09 36.1 5.8 8.3e-07 28.0 0.0 3.7 3 1 1 4 4 4 2 G-protein alpha subunit Ras PF00071.17 EMG50156.1 - 2.5e-08 33.4 1.9 8.5e-07 28.4 0.0 3.4 4 0 0 4 4 4 1 Ras family FeoB_N PF02421.13 EMG50156.1 - 9.3e-07 28.2 3.4 4.9e-05 22.6 0.0 3.9 5 0 0 5 5 5 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EMG50156.1 - 4.3e-05 22.7 0.1 0.0029 16.7 0.0 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EMG50156.1 - 6.5e-05 22.1 0.0 0.0011 18.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EMG50156.1 - 0.0017 18.1 0.0 0.026 14.3 0.0 2.9 3 0 0 3 3 3 1 Dynamin family AIG1 PF04548.11 EMG50156.1 - 0.035 13.2 1.4 0.039 13.0 0.0 1.8 2 0 0 2 2 2 0 AIG1 family MobB PF03205.9 EMG50156.1 - 0.05 13.2 0.4 11 5.7 0.2 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Sgf11 PF08209.6 EMG50157.1 - 0.0004 19.6 0.2 0.00059 19.1 0.1 1.3 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) DUF3505 PF12013.3 EMG50157.1 - 0.0031 17.7 1.6 0.0059 16.8 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) Elongin_A PF06881.6 EMG50157.1 - 0.007 16.7 0.3 0.013 15.8 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DHC PF09626.5 EMG50157.1 - 0.016 15.8 0.1 0.025 15.2 0.1 1.5 1 0 0 1 1 1 0 Dihaem cytochrome c DUF2256 PF10013.4 EMG50157.1 - 0.025 14.3 0.1 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) Rsm1 PF08600.5 EMG50157.1 - 0.078 12.8 0.3 0.17 11.7 0.2 1.5 1 0 0 1 1 1 0 Rsm1-like DUF4463 PF14703.1 EMG50157.1 - 0.1 13.1 0.4 0.46 11.0 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) 60KD_IMP PF02096.15 EMG50157.1 - 1.2 8.8 4.3 1.7 8.2 3.0 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein TRP PF06011.7 EMG50158.1 - 0.022 13.3 0.1 0.028 12.9 0.1 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF1673 PF07895.6 EMG50158.1 - 0.056 12.9 0.1 0.069 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) GCV_T PF01571.16 EMG50159.1 - 1.1e-63 214.4 0.0 1.3e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EMG50159.1 - 5.5e-16 58.3 0.0 8.8e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 EMG50159.1 - 6e-08 32.6 0.0 0.002 17.9 0.0 2.5 1 1 1 2 2 2 2 Sarcosine oxidase, gamma subunit family TrmE_N PF10396.4 EMG50159.1 - 0.059 13.3 0.0 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 GTP-binding protein TrmE N-terminus TPR_6 PF13174.1 EMG50159.1 - 0.13 12.7 0.4 2.6 8.6 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M41 PF01434.13 EMG50160.1 - 0.00064 19.2 0.4 0.00084 18.8 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M41 APC_CDC26 PF10471.4 EMG50162.1 - 1e-15 58.2 20.7 5.7e-15 55.8 14.4 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 MCLC PF05934.6 EMG50162.1 - 0.026 12.8 2.4 0.032 12.5 1.7 1.0 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) TraV PF09676.5 EMG50162.1 - 0.41 11.3 3.1 0.52 11.0 2.2 1.1 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) BAF1_ABF1 PF04684.8 EMG50162.1 - 3.3 6.4 10.8 3.6 6.3 7.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TMPIT PF07851.8 EMG50162.1 - 5 6.1 7.7 5.6 5.9 5.3 1.0 1 0 0 1 1 1 0 TMPIT-like protein LCD1 PF09798.4 EMG50162.1 - 6.1 4.7 11.2 6 4.7 7.8 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein Med3 PF11593.3 EMG50162.1 - 6.3 5.9 15.3 2.3 7.3 8.7 1.5 1 1 1 2 2 2 0 Mediator complex subunit 3 fungal p450 PF00067.17 EMG50163.1 - 9.1e-60 202.4 0.0 1.2e-59 202.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EMG50164.1 - 3.8e-60 203.7 0.0 5e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2304 PF10066.4 EMG50165.1 - 0.0053 16.6 5.2 0.01 15.6 3.6 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2304) TRP PF06011.7 EMG50167.1 - 5e-155 516.3 37.5 5e-155 516.3 26.0 1.4 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EMG50167.1 - 1.4e-45 154.8 2.8 2.2e-45 154.1 1.9 1.3 1 0 0 1 1 1 1 ML-like domain Neur_chan_memb PF02932.11 EMG50167.1 - 0.0096 15.8 0.2 0.067 13.0 0.0 2.4 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region KilA-N PF04383.8 EMG50168.1 - 1.2e-05 24.8 0.8 0.00016 21.2 0.0 2.9 2 1 0 2 2 2 1 KilA-N domain zf-C2H2 PF00096.21 EMG50170.1 - 3.5e-10 39.5 17.1 0.00067 19.8 1.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMG50170.1 - 4.2e-08 32.9 14.5 0.017 15.4 0.5 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMG50170.1 - 5.8e-06 26.3 13.5 0.00046 20.3 0.4 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMG50170.1 - 0.092 12.9 0.1 0.092 12.9 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 EMG50170.1 - 0.76 10.1 6.3 0.29 11.5 1.9 2.0 1 1 1 2 2 2 0 TRAF-type zinc finger zf-C2H2 PF00096.21 EMG50171.1 - 5.9e-09 35.7 15.8 8.2e-05 22.7 1.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMG50171.1 - 4.8e-08 32.7 13.9 0.0018 18.4 0.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EMG50171.1 - 3.5e-07 30.1 9.4 0.0032 17.6 0.4 3.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EMG50171.1 - 1.5e-05 25.0 18.1 4e-05 23.6 4.8 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMG50171.1 - 0.0012 18.8 11.5 0.02 15.0 1.0 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMG50171.1 - 0.071 13.0 6.5 0.38 10.7 0.8 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 EMG50171.1 - 1.3 8.8 13.9 0.1 12.3 1.3 3.1 3 0 0 3 3 3 0 BED zinc finger DUF4448 PF14610.1 EMG50172.1 - 1.7e-05 24.4 0.0 4.5e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.5 EMG50172.1 - 0.00012 21.3 0.0 0.00022 20.4 0.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_6 PF13964.1 EMG50172.1 - 0.00073 19.6 1.5 0.044 13.9 0.1 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 EMG50172.1 - 0.0025 17.9 1.3 0.03 14.4 0.1 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain FixQ PF05545.6 EMG50172.1 - 0.02 14.5 0.3 0.043 13.4 0.2 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF912 PF06024.7 EMG50172.1 - 0.021 14.8 0.0 0.021 14.8 0.0 3.1 4 0 0 4 4 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2762 PF10960.3 EMG50172.1 - 0.021 14.5 1.2 0.46 10.2 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) Kelch_4 PF13418.1 EMG50172.1 - 0.11 12.2 0.1 0.11 12.2 0.0 3.4 4 0 0 4 4 4 0 Galactose oxidase, central domain YajC PF02699.10 EMG50172.1 - 0.13 11.9 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit DUF1191 PF06697.7 EMG50172.1 - 0.14 10.9 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Kelch_1 PF01344.20 EMG50172.1 - 0.27 10.8 3.0 0.97 9.0 0.3 3.1 3 0 0 3 3 3 0 Kelch motif 2-oxoacid_dh PF00198.18 EMG50173.1 - 1.9e-80 269.4 0.1 3e-80 268.8 0.1 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EMG50173.1 - 4.3e-18 64.7 3.7 7.9e-18 63.8 2.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EMG50173.1 - 0.00011 21.7 1.8 0.03 13.9 0.6 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.14 EMG50173.1 - 0.00029 20.5 0.2 0.00061 19.4 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.1 EMG50173.1 - 0.025 14.2 0.3 0.099 12.3 0.2 2.0 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain MRP-L47 PF06984.8 EMG50174.1 - 1.3e-15 57.0 0.6 2.1e-15 56.3 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF2031 PF09592.5 EMG50175.1 - 0.0064 15.6 0.8 0.0072 15.5 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2031) adh_short PF00106.20 EMG50176.1 - 1.9e-19 70.2 0.0 2.4e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMG50176.1 - 4.2e-09 36.5 0.0 5.2e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMG50176.1 - 5.9e-08 32.5 0.0 9e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Glyco_tran_WecB PF03808.8 EMG50176.1 - 0.0023 17.3 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family THF_DHG_CYH_C PF02882.14 EMG50176.1 - 0.0031 16.6 0.0 0.0051 15.8 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 EMG50176.1 - 0.0067 16.4 0.0 0.057 13.4 0.0 2.1 2 1 0 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 EMG50176.1 - 0.019 14.1 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 EMG50176.1 - 0.043 12.6 0.0 0.056 12.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ribosomal_L17 PF01196.14 EMG50177.1 - 4.1e-23 81.7 0.1 6.3e-23 81.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 Pyr_redox_dim PF02852.17 EMG50178.1 - 1.9e-43 146.9 0.1 4.6e-43 145.7 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EMG50178.1 - 4.2e-40 137.7 15.1 1.9e-38 132.3 10.5 3.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMG50178.1 - 8.2e-20 71.0 12.3 3e-18 66.0 1.4 3.4 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMG50178.1 - 9.6e-13 47.7 7.6 1.6e-11 43.7 0.7 2.7 2 1 1 3 3 3 2 Glucose inhibited division protein A FAD_oxidored PF12831.2 EMG50178.1 - 1.7e-12 47.1 8.9 6.2e-11 42.0 0.4 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMG50178.1 - 1e-11 45.3 0.3 4.8e-08 33.3 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMG50178.1 - 1.9e-09 37.3 4.7 0.00087 19.2 0.3 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMG50178.1 - 7.4e-09 35.0 3.7 1.7e-05 24.0 0.1 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 EMG50178.1 - 1.2e-07 31.0 16.7 0.004 16.1 1.6 3.9 2 2 1 3 3 3 3 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMG50178.1 - 1.9e-07 30.3 3.5 1.9e-07 30.3 2.4 3.3 3 1 1 4 4 4 1 FAD binding domain HI0933_like PF03486.9 EMG50178.1 - 8.9e-07 27.7 11.8 0.00044 18.8 1.0 4.0 4 0 0 4 4 4 2 HI0933-like protein FAD_binding_3 PF01494.14 EMG50178.1 - 4.2e-06 26.0 9.6 0.021 13.8 0.6 3.5 3 1 0 3 3 3 3 FAD binding domain K_oxygenase PF13434.1 EMG50178.1 - 4.2e-05 22.6 1.0 0.024 13.5 0.0 3.0 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 EMG50178.1 - 0.00058 18.8 0.4 0.079 11.8 0.0 2.4 2 0 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EMG50178.1 - 0.00094 18.7 1.7 0.12 11.9 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EMG50178.1 - 0.004 16.8 0.6 0.004 16.8 0.4 2.6 3 0 0 3 3 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 EMG50178.1 - 0.022 15.0 0.0 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain UDPG_MGDP_dh_N PF03721.9 EMG50178.1 - 0.26 10.6 0.1 0.26 10.6 0.0 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.9 EMG50178.1 - 0.6 8.6 5.0 1.9 7.0 0.4 2.3 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.1 EMG50178.1 - 0.7 10.1 4.0 9.4 6.5 0.4 3.1 3 1 0 3 3 3 0 Putative NAD(P)-binding SNARE_assoc PF09335.6 EMG50179.1 - 8.6e-18 64.7 3.0 8.6e-18 64.7 2.1 3.1 3 1 0 3 3 3 1 SNARE associated Golgi protein 2OG-FeII_Oxy_4 PF13661.1 EMG50179.1 - 0.065 12.8 0.7 0.25 11.0 0.0 2.1 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily CbiQ PF02361.11 EMG50179.1 - 1.3 8.5 11.7 2.2 7.7 8.1 1.3 1 0 0 1 1 1 0 Cobalt transport protein NdhL PF10716.4 EMG50179.1 - 1.9 8.2 6.5 5.5 6.8 4.5 1.7 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit NOA36 PF06524.7 EMG50179.1 - 3.2 6.9 6.8 4.6 6.4 4.7 1.1 1 0 0 1 1 1 0 NOA36 protein Dsl1_C PF11989.3 EMG50180.1 - 6.5e-18 64.9 23.5 6.5e-18 64.9 16.3 3.6 3 2 0 3 3 3 1 Retrograde transport protein Dsl1 C terminal GspH PF12019.3 EMG50180.1 - 0.034 14.2 0.1 0.075 13.1 0.1 1.6 1 1 0 1 1 1 0 Type II transport protein GspH Med27 PF11571.3 EMG50180.1 - 0.047 13.8 0.8 3.5 7.8 0.0 3.4 3 0 0 3 3 3 0 Mediator complex subunit 27 Vac_Fusion PF02346.11 EMG50180.1 - 0.099 12.0 1.3 2.4 7.6 0.1 3.6 3 0 0 3 3 3 0 Chordopoxvirus fusion protein PEX11 PF05648.9 EMG50181.1 - 0.00077 18.7 1.1 0.0011 18.3 0.5 1.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) NAD_binding_6 PF08030.7 EMG50182.1 - 6.2e-25 87.9 0.0 1.3e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMG50182.1 - 2.5e-22 78.7 0.0 6.5e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EMG50182.1 - 2.5e-18 66.3 15.9 6.2e-18 65.0 11.0 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EMG50182.1 - 0.019 15.5 0.0 3.7 8.1 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Amidase PF01425.16 EMG50183.1 - 7.4e-96 321.6 0.0 9e-96 321.4 0.0 1.1 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.11 EMG50184.1 - 1.8e-28 99.2 16.8 1.8e-28 99.2 11.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Asp PF00026.18 EMG50186.1 - 3.4e-81 272.9 14.0 4e-81 272.7 9.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMG50186.1 - 0.00015 21.7 5.6 0.0002 21.3 2.0 2.2 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EMG50186.1 - 0.012 15.1 1.8 0.27 10.7 0.0 2.9 3 1 0 3 3 3 0 Xylanase inhibitor C-terminal PI3_PI4_kinase PF00454.22 EMG50187.1 - 1.9e-42 145.3 0.0 7e-42 143.4 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EMG50187.1 - 2.9e-23 82.0 1.2 1.2e-22 80.0 0.2 2.4 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) eIF-6 PF01912.13 EMG50188.1 - 2.1e-85 284.8 0.8 2.6e-85 284.5 0.6 1.1 1 0 0 1 1 1 1 eIF-6 family Phage_holin_6 PF10746.4 EMG50188.1 - 0.1 12.3 0.1 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 Phage holin family 6 GYF PF02213.11 EMG50189.1 - 7.7e-14 51.0 0.9 2.1e-13 49.6 0.6 1.8 1 0 0 1 1 1 1 GYF domain DUF3513 PF12026.3 EMG50189.1 - 0.22 11.0 1.6 0.39 10.2 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) ORC5_C PF14630.1 EMG50190.1 - 9.9e-35 120.2 0.1 1.5e-34 119.7 0.1 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EMG50190.1 - 1.1e-10 41.7 0.1 7.1e-10 39.1 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMG50190.1 - 1.5e-05 25.1 0.0 2.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EMG50190.1 - 0.00016 21.8 0.0 0.00028 21.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EMG50190.1 - 0.00022 21.0 0.7 0.00033 20.4 0.5 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 EMG50190.1 - 0.056 13.3 0.2 0.17 11.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMG50190.1 - 0.12 12.5 0.8 7.3 6.8 0.2 3.2 2 1 0 2 2 2 0 RNA helicase DUF2990 PF11693.3 EMG50190.1 - 0.25 11.2 1.4 4.1 7.3 0.2 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2990) RRM_1 PF00076.17 EMG50191.1 - 1.9e-08 33.8 0.0 4.5e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG50191.1 - 7.2e-07 29.0 0.0 1.8e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG50191.1 - 0.025 14.4 0.0 0.052 13.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC37_N PF03234.9 EMG50192.1 - 1.1e-63 214.7 9.3 1.1e-63 214.7 6.4 2.9 2 1 1 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EMG50192.1 - 2.7e-51 173.5 9.3 4.7e-51 172.6 4.4 2.3 2 1 0 2 2 2 1 Cdc37 Hsp90 binding domain Vpu PF00558.14 EMG50192.1 - 0.025 14.1 1.2 0.089 12.3 0.8 1.9 1 0 0 1 1 1 0 Vpu protein DUF2556 PF10831.3 EMG50192.1 - 0.058 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2556) E2_bind PF08825.5 EMG50192.1 - 0.15 11.8 2.5 35 4.2 0.2 3.5 2 1 1 3 3 3 0 E2 binding domain EutQ PF06249.7 EMG50193.1 - 2e-11 43.6 0.0 2.3e-11 43.4 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 EMG50193.1 - 1.4e-07 30.8 0.2 2e-07 30.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 EMG50193.1 - 9.1e-05 21.8 0.1 0.00015 21.1 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 EMG50193.1 - 0.00054 19.6 0.0 0.0008 19.0 0.0 1.3 1 1 0 1 1 1 1 Cupin Pirin PF02678.11 EMG50193.1 - 0.088 12.6 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Pirin ARD PF03079.9 EMG50193.1 - 0.11 12.4 0.1 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 ARD/ARD' family VPS9 PF02204.13 EMG50194.1 - 5.6e-30 103.4 0.5 1.3e-29 102.2 0.3 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EMG50194.1 - 3.4e-08 32.8 0.1 8.4e-08 31.5 0.0 1.7 1 0 0 1 1 1 1 CUE domain Fe-S_biosyn PF01521.15 EMG50195.1 - 9.9e-20 70.5 0.0 1.6e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3853 PF12964.2 EMG50195.1 - 0.093 12.5 0.0 0.49 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3853) F-actin_cap_A PF01267.12 EMG50196.1 - 0.0019 17.3 0.5 0.0025 16.9 0.3 1.3 1 1 0 1 1 1 1 F-actin capping protein alpha subunit Med15_fungi PF05397.7 EMG50196.1 - 0.085 12.8 0.3 0.29 11.1 0.2 1.8 1 1 0 1 1 1 0 Mediator complex subunit 15 DUF1828 PF08861.5 EMG50196.1 - 0.13 11.9 0.6 1.7 8.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF1828 LRR_5 PF13306.1 EMG50198.1 - 0.0043 16.7 0.2 0.0087 15.7 0.1 1.5 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) GFO_IDH_MocA PF01408.17 EMG50199.1 - 1.5e-19 70.6 0.3 1.8e-18 67.1 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EMG50199.1 - 1e-05 25.3 0.0 2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Mfa2 PF08842.5 EMG50199.1 - 0.013 14.8 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 Fimbrillin-A associated anchor proteins Mfa1 and Mfa2 NTPase_1 PF03266.10 EMG50199.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 NTPase Sec20 PF03908.8 EMG50200.1 - 1.7e-35 120.5 2.9 1.7e-35 120.5 2.0 2.6 3 0 0 3 3 3 1 Sec20 IF3_C PF00707.17 EMG50200.1 - 1 9.1 4.6 0.51 10.1 0.7 2.4 2 0 0 2 2 2 0 Translation initiation factor IF-3, C-terminal domain Exo_endo_phos PF03372.18 EMG50201.1 - 2.1e-17 63.8 0.2 3e-17 63.4 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Mob1_phocein PF03637.12 EMG50202.1 - 3.8e-23 82.0 0.0 5.2e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family WAC_Acf1_DNA_bd PF10537.4 EMG50203.1 - 7.8e-40 135.1 0.7 3.5e-39 133.0 0.5 2.3 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EMG50203.1 - 1.1e-11 44.2 0.0 3.3e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 EMG50203.1 - 7.7e-07 28.7 0.2 3e-06 26.9 0.1 2.1 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 EMG50203.1 - 0.00016 21.3 0.2 0.0011 18.7 0.3 2.3 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 3 Ubiq_cyt_C_chap PF03981.7 EMG50205.1 - 4.2e-38 130.3 0.2 6.4e-38 129.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone SRP72 PF08492.7 EMG50206.1 - 2.5e-11 43.7 4.8 2.5e-11 43.7 3.3 2.6 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_12 PF13424.1 EMG50206.1 - 1.9e-06 27.7 4.2 0.033 14.1 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMG50206.1 - 0.00022 21.7 0.0 1.1 10.0 0.1 3.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMG50206.1 - 0.00029 21.0 4.7 0.041 14.3 0.1 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMG50206.1 - 0.00088 18.8 2.8 0.7 9.8 0.2 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EMG50206.1 - 0.0013 18.8 15.7 0.068 13.3 0.8 4.6 3 2 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EMG50206.1 - 0.0013 18.4 15.2 0.0058 16.4 0.5 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMG50206.1 - 0.0023 18.2 4.9 0.37 11.1 0.1 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMG50206.1 - 0.0042 16.7 10.3 0.4 10.5 0.1 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.15 EMG50206.1 - 0.013 15.4 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 0 PPR repeat TPR_14 PF13428.1 EMG50206.1 - 0.023 15.3 0.0 1 10.1 0.0 3.6 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMG50206.1 - 0.035 13.7 6.8 0.46 10.1 0.3 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.4 EMG50206.1 - 0.05 12.9 3.3 2.3 7.5 0.1 2.9 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_10 PF13374.1 EMG50206.1 - 0.073 13.0 0.0 2.1 8.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 EMG50206.1 - 0.14 11.6 0.4 0.96 8.8 0.1 2.1 1 1 1 2 2 2 0 Foie gras liver health family 1 TPR_11 PF13414.1 EMG50206.1 - 0.19 11.4 10.6 1.2 8.8 0.3 4.1 3 1 0 4 4 4 0 TPR repeat LIP PF03583.9 EMG50207.1 - 2.5e-110 368.2 0.0 2.9e-110 368.0 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 EMG50207.1 - 0.00011 22.1 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMG50207.1 - 0.00044 20.0 0.0 0.001 18.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMG50207.1 - 0.1 11.7 0.9 10 5.2 0.1 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase family NUDIX PF00293.23 EMG50208.1 - 1.1e-13 50.9 0.1 2.2e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 EMG50208.1 - 6.5e-08 31.9 0.1 1.1e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NUDIX-like PF09296.6 EMG50208.1 - 0.00081 19.6 0.0 0.0036 17.5 0.0 2.2 2 1 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zinc_ribbon_2 PF13240.1 EMG50208.1 - 0.057 12.9 0.7 0.2 11.2 0.5 1.9 1 0 0 1 1 1 0 zinc-ribbon domain Nudix_N_2 PF14803.1 EMG50208.1 - 0.61 9.8 2.3 1.9 8.2 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal Sec5 PF15469.1 EMG50209.1 - 4.3e-39 134.1 18.5 4.3e-39 134.1 12.9 3.4 4 0 0 4 4 4 1 Exocyst complex component Sec5 DDE_1 PF03184.14 EMG50210.1 - 4.5e-32 110.9 0.1 1e-31 109.8 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EMG50210.1 - 8.3e-08 31.9 0.1 1.1e-06 28.2 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain GDPD PF03009.12 EMG50211.1 - 5.9e-21 75.1 0.0 1.4e-20 73.8 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Myb_DNA-bind_6 PF13921.1 EMG50213.1 - 2.8e-19 68.9 6.6 4.4e-14 52.3 0.3 3.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EMG50213.1 - 1.9e-14 53.4 2.4 7.1e-10 38.7 0.1 3.7 5 0 0 5 5 5 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EMG50213.1 - 1.4e-05 25.1 3.1 1.4e-05 25.1 2.2 4.4 3 2 1 4 4 4 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EMG50213.1 - 0.00035 20.4 3.8 0.0011 18.8 0.4 3.1 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain HTH_37 PF13744.1 EMG50213.1 - 0.015 15.1 0.1 0.037 13.8 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain ACOX PF01756.14 EMG50214.1 - 3.7e-46 156.8 0.0 6.7e-46 156.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 EMG50214.1 - 8.6e-16 57.1 0.6 2e-15 56.0 0.4 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 EMG50214.1 - 2.7e-11 43.8 0.0 7e-11 42.5 0.0 1.7 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 EMG50214.1 - 9.2e-06 25.8 0.2 0.00097 19.2 0.0 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain MFS_1 PF07690.11 EMG50215.1 - 3.8e-20 71.9 26.7 5.7e-20 71.3 16.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2887 PF11103.3 EMG50215.1 - 0.013 15.0 0.1 0.02 14.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2887) Hpre_diP_synt_I PF07456.6 EMG50215.1 - 0.047 13.5 0.3 0.047 13.5 0.2 2.8 4 0 0 4 4 4 0 Heptaprenyl diphosphate synthase component I Metallophos PF00149.23 EMG50216.1 - 3.8e-42 143.9 1.9 5.7e-42 143.3 1.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MoCF_biosynth PF00994.19 EMG50217.1 - 9.1e-28 96.4 0.0 1.6e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain MFS_1 PF07690.11 EMG50218.1 - 1e-54 185.5 89.2 5.2e-29 101.0 22.6 3.4 2 2 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG50218.1 - 5.2e-09 35.1 76.6 0.0061 15.1 9.1 5.4 2 2 0 3 3 3 3 Sugar (and other) transporter MFS_2 PF13347.1 EMG50218.1 - 4.4e-08 31.9 32.5 1.1e-05 23.9 8.3 4.2 3 2 1 4 4 4 2 MFS/sugar transport protein Ion_trans_N PF08412.5 EMG50218.1 - 0.097 11.9 1.5 11 5.3 0.0 3.5 3 0 0 3 3 3 0 Ion transport protein N-terminal ChlI PF13541.1 EMG50218.1 - 0.12 11.8 0.0 15 5.1 0.0 2.4 2 0 0 2 2 2 0 Subunit ChlI of Mg-chelatase Syja_N PF02383.13 EMG50219.1 - 7e-92 307.5 3.4 7e-92 307.5 2.4 2.9 3 1 1 4 4 4 1 SacI homology domain RR_TM4-6 PF06459.7 EMG50219.1 - 0.53 10.1 14.5 1.1 9.0 10.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ABC2_membrane PF01061.19 EMG50220.1 - 8e-07 28.4 2.2 1.1e-06 28.0 1.5 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EMG50221.1 - 8.2e-16 58.5 0.0 9.8e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EMG50221.1 - 2.5e-05 23.5 0.0 3.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EMG50221.1 - 3.4e-05 23.3 0.0 4.6e-05 22.9 0.0 1.3 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 EMG50221.1 - 0.00012 21.6 0.7 0.00019 20.9 0.1 1.6 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EMG50221.1 - 0.00031 21.5 0.0 0.00085 20.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMG50221.1 - 0.001 19.3 0.1 0.0022 18.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EMG50221.1 - 0.0021 17.5 0.2 0.0085 15.5 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EMG50221.1 - 0.0022 18.0 0.0 0.0027 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMG50221.1 - 0.0049 17.0 0.0 0.0068 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EMG50221.1 - 0.0058 16.2 0.2 0.01 15.4 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EMG50221.1 - 0.015 15.0 0.2 0.023 14.3 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_21 PF13304.1 EMG50221.1 - 0.017 15.1 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.4 EMG50221.1 - 0.019 13.5 0.1 0.028 12.9 0.1 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_33 PF13671.1 EMG50221.1 - 0.019 14.8 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMG50221.1 - 0.026 14.6 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.1 EMG50221.1 - 0.033 14.4 0.5 0.06 13.6 0.3 1.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMG50221.1 - 0.044 13.5 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain MMR_HSR1 PF01926.18 EMG50221.1 - 0.058 13.3 0.1 0.089 12.7 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.1 EMG50221.1 - 0.064 13.2 0.1 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EMG50221.1 - 0.093 12.2 0.1 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 EMG50221.1 - 0.1 12.1 0.1 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Herpes_Helicase PF02689.9 EMG50221.1 - 0.11 10.1 0.0 0.12 10.1 0.0 1.1 1 0 0 1 1 1 0 Helicase AAA PF00004.24 EMG50221.1 - 0.12 12.5 0.0 0.17 12.1 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.13 EMG50221.1 - 0.13 11.2 0.2 0.2 10.6 0.1 1.4 1 1 0 1 1 1 0 Septin AAA_15 PF13175.1 EMG50221.1 - 0.16 10.9 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain PDR_CDR PF06422.7 EMG50222.1 - 5.7e-28 96.6 0.0 9e-28 95.9 0.0 1.3 1 0 0 1 1 1 1 CDR ABC transporter ABC2_membrane PF01061.19 EMG50222.1 - 5.5e-12 45.3 2.1 5.5e-12 45.3 1.5 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 EMG50222.1 - 0.00042 19.4 5.1 0.0022 17.1 3.5 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein Cyclin PF08613.6 EMG50223.1 - 3.2e-32 111.9 4.2 9.3e-32 110.5 3.0 1.8 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EMG50223.1 - 0.00034 20.1 1.4 0.00061 19.3 0.3 1.9 1 1 1 2 2 2 1 Cyclin, N-terminal domain SieB PF14163.1 EMG50223.1 - 0.011 15.2 0.1 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Superinfection exclusion protein B RXT2_N PF08595.6 EMG50223.1 - 0.61 9.8 11.5 0.98 9.2 4.9 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal FYDLN_acid PF09538.5 EMG50223.1 - 5.2 7.6 22.8 1.2 9.7 10.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF3295 PF11702.3 EMG50223.1 - 8.5 5.2 21.5 0.88 8.4 8.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) GET2 PF08690.5 EMG50223.1 - 9.9 5.3 14.3 0.93 8.6 0.4 2.2 2 0 0 2 2 2 0 GET complex subunit GET2 ABC_trans_N PF14510.1 EMG50224.1 - 1.7e-12 47.2 0.0 3.3e-12 46.3 0.0 1.5 1 1 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC_tran PF00005.22 EMG50224.1 - 9.5e-06 25.9 0.0 2.2e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_25 PF13481.1 EMG50224.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Inhibitor_I29 PF08246.7 EMG50224.1 - 0.12 12.6 1.1 0.28 11.4 0.7 1.6 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) DUF908 PF06012.7 EMG50225.1 - 0.076 12.3 1.2 0.18 11.1 0.8 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SHMT PF00464.14 EMG50226.1 - 2.7e-210 697.7 0.0 3.2e-210 697.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 EMG50226.1 - 1.3e-07 30.8 0.0 3.1e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EMG50226.1 - 3.4e-06 26.0 0.0 4.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EMG50226.1 - 0.0054 15.9 0.0 0.01 15.0 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase UDPG_MGDP_dh_N PF03721.9 EMG50226.1 - 0.076 12.3 0.0 0.71 9.2 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Cut12 PF11500.3 EMG50226.1 - 0.17 11.5 0.8 0.26 10.9 0.0 1.6 2 0 0 2 2 2 0 Spindle pole body formation-associated protein ORMDL PF04061.9 EMG50227.1 - 4.3e-58 194.7 5.1 5.6e-58 194.3 3.6 1.1 1 0 0 1 1 1 1 ORMDL family LAP1C PF05609.7 EMG50227.1 - 0.039 12.6 0.1 0.049 12.2 0.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RCC1 PF00415.13 EMG50228.1 - 1.2e-18 67.0 1.8 0.0012 19.0 0.0 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMG50228.1 - 1.2e-14 53.4 19.2 3e-09 36.2 0.1 6.5 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat NapE PF06796.6 EMG50228.1 - 0.17 11.2 1.0 0.37 10.1 0.7 1.5 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE Sugar_tr PF00083.19 EMG50229.1 - 7.2e-108 361.0 24.5 8.3e-108 360.8 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG50229.1 - 7.7e-23 80.7 37.6 1.1e-15 57.2 10.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG50230.1 - 1e-105 353.9 25.4 1.2e-105 353.6 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG50230.1 - 3.4e-18 65.5 36.9 1.2e-12 47.2 7.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily HlyIII PF03006.15 EMG50231.1 - 8.3e-54 182.3 11.4 1.3e-53 181.7 7.9 1.2 1 0 0 1 1 1 1 Haemolysin-III related Flavi_M PF01004.14 EMG50233.1 - 0.095 12.1 0.1 0.095 12.1 0.1 1.9 2 1 1 3 3 3 0 Flavivirus envelope glycoprotein M NAD_binding_2 PF03446.10 EMG50234.1 - 2.2e-36 125.1 0.0 3.2e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EMG50234.1 - 4e-17 62.4 0.0 6.5e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase GFO_IDH_MocA PF01408.17 EMG50234.1 - 0.00048 20.6 0.0 0.0026 18.2 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold OCD_Mu_crystall PF02423.10 EMG50234.1 - 0.14 10.8 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family NAD_binding_1 PF00175.16 EMG50235.1 - 8.5e-25 87.4 0.0 1.3e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EMG50235.1 - 1.7e-22 79.4 0.0 2.7e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EMG50235.1 - 9.2e-08 32.1 0.1 0.00021 21.2 0.0 2.6 2 1 1 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EMG50235.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain SR-25 PF10500.4 EMG50236.1 - 0.00051 19.5 4.7 0.00074 19.0 3.3 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF605 PF04652.11 EMG50236.1 - 0.02 14.3 9.4 0.022 14.1 6.5 1.1 1 0 0 1 1 1 0 Vta1 like DUF966 PF06136.8 EMG50236.1 - 0.075 12.4 5.2 0.092 12.1 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4614 PF15391.1 EMG50236.1 - 0.078 12.7 11.3 0.12 12.1 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) TraG-D_C PF12696.2 EMG50236.1 - 0.35 10.7 2.9 0.52 10.1 2.0 1.3 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG DNA_pol_viral_N PF00242.12 EMG50236.1 - 0.83 8.6 6.3 0.98 8.3 4.4 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 EMG50236.1 - 1.2 7.2 8.0 1.3 7.2 5.5 1.1 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 EMG50236.1 - 1.3 8.8 8.5 1.5 8.6 5.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAP1 PF07218.6 EMG50236.1 - 1.7 6.6 9.8 1.9 6.4 6.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Arrestin_C PF02752.17 EMG50238.1 - 1.9e-17 63.6 0.6 3.6e-13 49.7 0.0 2.8 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EMG50238.1 - 3.2e-10 40.0 0.0 3.5e-07 30.1 0.1 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain RNA_pol_Rpc34 PF05158.7 EMG50240.1 - 3.8e-86 289.2 3.4 4.2e-86 289.0 2.4 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_36 PF13730.1 EMG50240.1 - 3.8e-05 23.7 0.8 0.043 13.9 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain Rrf2 PF02082.15 EMG50240.1 - 0.0097 16.0 1.4 0.018 15.1 0.1 1.9 2 0 0 2 2 2 1 Transcriptional regulator RPA_C PF08784.6 EMG50240.1 - 0.028 14.8 0.1 0.11 12.9 0.0 1.9 2 0 0 2 2 2 0 Replication protein A C terminal TrmB PF01978.14 EMG50240.1 - 0.037 13.7 0.5 0.12 12.0 0.1 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.1 EMG50240.1 - 0.047 13.7 1.1 0.37 10.8 0.1 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain DUF3431 PF11913.3 EMG50240.1 - 0.06 12.8 0.1 0.11 11.9 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3431) Cyclin_C PF02984.14 EMG50240.1 - 0.11 12.4 1.8 0.24 11.3 0.5 2.0 2 1 0 2 2 2 0 Cyclin, C-terminal domain EIAV_GP90 PF00971.13 EMG50241.1 - 0.14 10.5 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 EIAV coat protein, gp90 OTCace_N PF02729.16 EMG50242.1 - 3.1e-42 143.5 0.2 6.1e-42 142.6 0.1 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EMG50242.1 - 3.1e-41 140.8 0.1 5.2e-41 140.1 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Epimerase PF01370.16 EMG50243.1 - 2.2e-18 66.5 0.1 2.8e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMG50243.1 - 7.1e-16 57.7 0.1 1e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMG50243.1 - 1.5e-10 40.4 0.1 2e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EMG50243.1 - 4.9e-10 39.7 0.9 2.5e-09 37.4 0.6 2.1 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMG50243.1 - 0.00012 21.4 0.5 0.0005 19.3 0.1 2.1 2 1 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EMG50243.1 - 0.0016 18.4 0.0 0.0038 17.1 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EMG50243.1 - 0.0019 17.1 0.4 0.0035 16.2 0.3 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein HAD PF12710.2 EMG50243.1 - 0.038 14.1 0.2 4.1 7.5 0.0 2.6 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase KR PF08659.5 EMG50243.1 - 0.038 13.6 0.1 0.25 11.0 0.1 2.0 1 1 0 1 1 1 0 KR domain DUF3589 PF12141.3 EMG50245.1 - 1.8e-153 511.3 0.9 4.7e-153 510.0 0.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) AIF_C PF14721.1 EMG50245.1 - 7.1 6.8 10.0 11 6.3 4.6 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Anp1 PF03452.9 EMG50246.1 - 4.4e-61 206.4 0.3 5.5e-61 206.0 0.2 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 EMG50246.1 - 0.04 13.5 0.1 0.083 12.5 0.1 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 MSC PF09402.5 EMG50247.1 - 3.5e-98 328.4 0.3 9.5e-98 326.9 0.2 1.8 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EMG50247.1 - 3.4e-10 39.3 1.3 7.3e-10 38.2 0.0 2.4 2 0 0 2 2 2 1 HeH/LEM domain MttA_Hcf106 PF02416.11 EMG50247.1 - 0.035 13.2 0.2 0.19 10.8 0.0 2.5 2 0 0 2 2 2 0 mttA/Hcf106 family EndIII_4Fe-2S PF10576.4 EMG50247.1 - 0.13 12.4 4.3 0.31 11.3 3.0 1.7 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Wzy_C PF04932.10 EMG50247.1 - 0.17 11.6 0.3 0.28 10.9 0.2 1.5 1 1 0 1 1 1 0 O-Antigen ligase Vps51 PF08700.6 EMG50248.1 - 1.7e-07 30.9 2.5 1.7e-07 30.9 1.7 1.9 2 0 0 2 2 2 1 Vps51/Vps67 NPR1_like_C PF12313.3 EMG50248.1 - 0.013 14.9 0.1 0.021 14.2 0.1 1.4 1 0 0 1 1 1 0 NPR1/NIM1 like defence protein C terminal DUF4559 PF15112.1 EMG50248.1 - 0.06 12.5 7.3 0.022 13.9 2.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) BPL_LplA_LipB PF03099.14 EMG50249.1 - 2.7e-15 56.4 0.0 5.1e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF1989 PF09347.5 EMG50250.1 - 3.4e-54 182.7 0.0 4.6e-54 182.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) FeS PF04060.8 EMG50250.1 - 0.025 14.1 0.3 0.068 12.7 0.0 1.9 2 0 0 2 2 2 0 Putative Fe-S cluster MFS_1 PF07690.11 EMG50251.1 - 2e-18 66.2 24.9 1.1e-17 63.7 15.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2887 PF11103.3 EMG50251.1 - 0.024 14.2 0.1 0.039 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2887) DUF3589 PF12141.3 EMG50252.1 - 3.3e-151 503.9 4.5 4.3e-151 503.5 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3589) FBA PF04300.8 EMG50252.1 - 0.008 16.1 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 F-box associated region PfkB PF00294.19 EMG50253.1 - 6.6e-71 238.8 0.3 7.8e-71 238.6 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EMG50253.1 - 2.6e-06 26.8 0.0 4.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Spb1_C PF07780.7 EMG50254.1 - 4.8e-76 255.0 29.1 4.8e-76 255.0 20.2 4.0 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 EMG50254.1 - 4e-53 180.0 0.1 4.6e-52 176.6 0.0 2.4 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.3 EMG50254.1 - 6e-52 175.3 15.4 6e-52 175.3 10.7 5.3 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) GMC_oxred_C PF05199.8 EMG50257.1 - 4.8e-25 88.5 0.0 6.3e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMG50258.1 - 4.3e-31 108.1 0.0 5.2e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EMG50258.1 - 0.00013 21.0 0.0 0.0002 20.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMG50258.1 - 0.00025 21.0 0.1 0.00058 19.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMG50258.1 - 0.0079 16.0 0.2 0.011 15.6 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMG50258.1 - 0.077 12.0 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain CBS PF00571.23 EMG50260.1 - 0.061 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 CBS domain DBR1 PF05011.8 EMG50261.1 - 2.7e-11 43.5 1.5 6.1e-11 42.3 0.2 2.1 1 1 1 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EMG50261.1 - 2.7e-06 26.9 3.9 5.7e-06 25.8 2.7 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Arginase PF00491.16 EMG50263.1 - 2.7e-86 289.3 0.0 3.2e-86 289.0 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EMG50263.1 - 0.029 14.5 0.8 0.049 13.8 0.6 1.3 1 0 0 1 1 1 0 UPF0489 domain F-box-like PF12937.2 EMG50264.1 - 5.2e-06 26.0 0.0 1.5e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMG50264.1 - 2.6e-05 23.7 0.1 0.00013 21.4 0.0 2.2 2 0 0 2 2 2 1 F-box domain PRANC PF09372.5 EMG50264.1 - 0.11 12.4 2.5 0.14 12.1 0.0 2.5 3 0 0 3 3 3 0 PRANC domain Malic_M PF03949.10 EMG50265.1 - 1.4e-78 264.0 0.0 2e-78 263.4 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EMG50265.1 - 1.9e-62 210.0 0.0 3.9e-62 209.0 0.0 1.5 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Zn_clus PF00172.13 EMG50266.1 - 1.2e-06 28.2 6.1 2.2e-06 27.4 4.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_1 PF00175.16 EMG50267.1 - 5.1e-25 88.1 0.0 8.3e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EMG50267.1 - 5.3e-22 77.8 0.0 9.3e-22 77.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EMG50267.1 - 5.1e-08 32.9 0.1 0.00014 21.7 0.0 2.7 2 1 1 3 3 3 2 Ferric reductase NAD binding domain Mito_carr PF00153.22 EMG50268.1 - 1.5e-29 101.4 0.7 1e-14 53.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein NAD_Gly3P_dh_N PF01210.18 EMG50269.1 - 4.2e-52 176.0 0.0 6.9e-52 175.3 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EMG50269.1 - 6.6e-39 133.0 0.0 1.1e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 EMG50269.1 - 0.00019 21.8 0.4 0.2 12.0 0.0 2.6 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 EMG50269.1 - 0.0066 16.7 0.0 0.015 15.5 0.0 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain ComX PF05952.7 EMG50269.1 - 0.034 13.6 0.1 0.23 10.9 0.0 2.4 2 0 0 2 2 2 0 Bacillus competence pheromone ComX Med15 PF09606.5 EMG50270.1 - 2.4 6.2 64.3 3.2 5.8 44.6 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Carb_kinase PF01256.12 EMG50271.1 - 5.6e-51 173.1 0.0 9.1e-50 169.1 0.0 2.0 1 1 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 EMG50271.1 - 0.00094 18.4 0.0 0.002 17.3 0.0 1.6 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.7 EMG50271.1 - 0.016 14.3 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase PfkB PF00294.19 EMG50271.1 - 0.079 12.0 0.4 0.24 10.4 0.3 2.0 1 1 0 1 1 1 0 pfkB family carbohydrate kinase TPR_11 PF13414.1 EMG50273.1 - 0.023 14.3 4.6 0.2 11.3 0.4 2.4 2 0 0 2 2 2 0 TPR repeat TPR_12 PF13424.1 EMG50273.1 - 0.14 12.1 2.8 12 5.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2357 PF09823.4 EMG50274.1 - 0.016 14.2 1.3 0.031 13.3 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) Ribosomal_L23 PF00276.15 EMG50275.1 - 1.2e-21 76.4 1.2 1.2e-21 76.4 0.8 1.8 2 0 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 EMG50275.1 - 2.9e-21 75.2 8.8 2.9e-21 75.2 6.1 1.9 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_S11 PF00411.14 EMG50276.1 - 4.6e-06 26.7 0.0 7.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S11 PLA2_B PF01735.13 EMG50277.1 - 4.9e-198 658.2 5.1 6.5e-198 657.8 3.5 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain C1_4 PF07975.7 EMG50277.1 - 0.07 13.1 0.5 0.14 12.1 0.4 1.5 1 0 0 1 1 1 0 TFIIH C1-like domain PLA2_B PF01735.13 EMG50278.1 - 4.4e-188 625.4 4.5 5.4e-188 625.1 3.1 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PLA2_B PF01735.13 EMG50279.1 - 1.9e-185 616.7 2.1 1.9e-185 616.7 1.4 1.4 2 0 0 2 2 2 1 Lysophospholipase catalytic domain C1_4 PF07975.7 EMG50279.1 - 0.055 13.4 0.5 0.11 12.4 0.4 1.5 1 0 0 1 1 1 0 TFIIH C1-like domain ADK PF00406.17 EMG50280.1 - 4.7e-60 201.8 0.0 6.8e-60 201.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EMG50280.1 - 1.3e-14 53.5 0.0 3.7e-14 52.0 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EMG50280.1 - 9.2e-05 22.3 0.0 0.00015 21.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMG50280.1 - 0.00011 22.9 0.0 0.00022 22.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMG50280.1 - 0.00067 19.9 0.2 0.0021 18.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMG50280.1 - 0.085 11.9 0.1 0.17 10.9 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 EMG50280.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain CFIA_Pcf11 PF11526.3 EMG50281.1 - 5.1e-19 68.2 6.3 5.1e-19 68.2 4.4 2.6 2 1 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 Endonuclease_7 PF02945.10 EMG50281.1 - 0.014 15.1 0.5 0.43 10.3 0.0 2.4 2 0 0 2 2 2 0 Recombination endonuclease VII DUF2175 PF09943.4 EMG50281.1 - 0.11 12.5 11.4 10 6.2 0.6 4.2 4 0 0 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2175) zf-BED PF02892.10 EMG50281.1 - 0.15 11.8 1.2 1.4 8.7 0.1 2.6 2 0 0 2 2 2 0 BED zinc finger zf-C3HC4_3 PF13920.1 EMG50281.1 - 0.18 11.4 0.6 2.4 7.8 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) C1_2 PF03107.11 EMG50281.1 - 0.25 11.4 1.7 6.6 6.9 0.1 2.4 2 0 0 2 2 2 0 C1 domain GCC2_GCC3 PF07699.8 EMG50281.1 - 0.29 10.7 2.8 0.47 10.0 0.4 2.1 2 0 0 2 2 2 0 GCC2 and GCC3 DEAD PF00270.24 EMG50282.1 - 8.5e-36 122.9 0.3 1.8e-35 121.9 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG50282.1 - 7.1e-23 80.2 0.1 4.8e-11 42.3 0.0 3.4 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 EMG50282.1 - 2.5e-06 27.4 7.2 3.2e-06 27.0 0.1 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CENP-B_dimeris PF09026.5 EMG50282.1 - 0.018 15.2 0.8 0.049 13.8 0.3 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 EMG50282.1 - 1.9 8.8 8.0 6.2 7.2 5.5 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HAD_2 PF13419.1 EMG50283.1 - 9.1e-12 45.5 0.0 1.1e-11 45.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMG50283.1 - 5.1e-07 30.3 0.0 4.2e-05 24.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMG50283.1 - 0.00065 19.3 0.0 0.0016 18.1 0.0 1.7 1 1 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EMG50283.1 - 0.0036 17.4 0.0 0.0043 17.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EMG50283.1 - 0.023 14.5 0.0 6.4 6.7 0.0 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase YL1 PF05764.8 EMG50284.1 - 1.1e-51 175.7 53.9 1.1e-51 175.7 37.4 4.5 3 2 1 4 4 4 1 YL1 nuclear protein YL1_C PF08265.6 EMG50284.1 - 6.2e-11 41.6 0.1 9.8e-11 41.0 0.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Aha1_N PF09229.6 EMG50285.1 - 5.6e-37 126.6 2.4 6.6e-37 126.3 1.7 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal Gemini_coat PF00844.13 EMG50285.1 - 0.075 12.2 0.0 0.096 11.9 0.0 1.2 1 0 0 1 1 1 0 Geminivirus coat protein/nuclear export factor BR1 family MFS_1 PF07690.11 EMG50286.1 - 1e-40 139.5 28.8 1e-40 139.5 20.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Fapy_DNA_glyco PF01149.19 EMG50287.1 - 9e-27 93.7 0.1 1.5e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 EMG50287.1 - 1.6e-25 88.6 0.0 4.2e-25 87.3 0.0 1.8 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase H2TH domain Snf7 PF03357.16 EMG50288.1 - 1.8e-45 154.3 13.3 2.2e-45 154.1 9.2 1.0 1 0 0 1 1 1 1 Snf7 Seryl_tRNA_N PF02403.17 EMG50288.1 - 0.042 13.8 13.3 0.062 13.3 2.3 2.6 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Exonuc_VII_L PF02601.10 EMG50288.1 - 0.062 12.4 5.5 0.075 12.2 3.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1395 PF07160.7 EMG50288.1 - 0.28 10.6 7.3 0.52 9.7 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1395) Prefoldin_2 PF01920.15 EMG50288.1 - 0.29 10.9 0.0 0.29 10.9 0.0 3.6 2 1 1 3 3 2 0 Prefoldin subunit DUF4337 PF14235.1 EMG50288.1 - 1 9.1 5.9 0.21 11.4 1.2 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4337) FlaC_arch PF05377.6 EMG50288.1 - 1.6 8.7 0.0 1.6 8.7 0.0 3.7 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) DUF2802 PF10975.3 EMG50288.1 - 1.6 8.5 5.0 0.79 9.5 0.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) Reo_sigmaC PF04582.7 EMG50288.1 - 1.7 7.7 6.2 6.6 5.8 2.7 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Atg14 PF10186.4 EMG50288.1 - 1.9 7.3 8.7 2.9 6.7 6.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 EMG50288.1 - 3 6.1 12.8 1.4 7.2 4.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) FliJ PF02050.11 EMG50288.1 - 4.2 7.4 13.9 6 6.9 3.5 2.8 1 1 2 3 3 3 0 Flagellar FliJ protein NPV_P10 PF05531.7 EMG50288.1 - 4.9 7.4 13.5 5.2 7.3 0.0 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4446 PF14584.1 EMG50288.1 - 5.6 6.7 7.9 10 5.9 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) COG2 PF06148.6 EMG50288.1 - 6.4 6.6 8.8 4.8 7.0 0.9 2.9 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Methyltransf_23 PF13489.1 EMG50289.1 - 1.1e-19 70.6 0.0 1.7e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMG50289.1 - 7.5e-17 61.3 0.0 1.2e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMG50289.1 - 1.2e-15 57.7 0.0 2.3e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMG50289.1 - 2e-11 44.4 0.0 3.1e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMG50289.1 - 4.8e-11 43.0 0.0 9.4e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMG50289.1 - 2.9e-07 30.7 0.0 5.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMG50289.1 - 6.8e-07 28.6 0.0 9.2e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EMG50289.1 - 3.2e-06 26.6 0.0 7e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 EMG50289.1 - 2.8e-05 23.0 0.0 4.5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.13 EMG50289.1 - 5.7e-05 22.3 0.0 8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 EMG50289.1 - 6e-05 22.3 0.0 8.9e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 EMG50289.1 - 0.0008 18.8 0.3 0.0022 17.4 0.2 1.7 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 EMG50289.1 - 0.0019 18.1 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EMG50289.1 - 0.0026 17.2 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) DREV PF05219.7 EMG50289.1 - 0.0036 16.2 0.1 0.0067 15.3 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_32 PF13679.1 EMG50289.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cofilin_ADF PF00241.15 EMG50289.1 - 0.037 13.9 0.0 0.09 12.6 0.0 1.6 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein Lipoprotein_9 PF03180.9 EMG50290.1 - 0.0002 20.3 0.2 0.00027 19.8 0.1 1.2 1 0 0 1 1 1 1 NLPA lipoprotein PH PF00169.24 EMG50291.1 - 1e-14 54.6 3.2 8.1e-14 51.6 1.7 2.5 2 0 0 2 2 2 1 PH domain Ribosomal_L14 PF00238.14 EMG50292.1 - 4.4e-32 110.3 0.0 4.9e-32 110.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e LIM PF00412.17 EMG50293.1 - 1.1e-10 41.4 26.3 1.3e-05 25.1 6.7 2.6 2 0 0 2 2 2 2 LIM domain Glyco_hydro_81 PF03639.8 EMG50294.1 - 8.6e-209 695.0 2.1 1.1e-208 694.7 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Zn_clus PF00172.13 EMG50295.1 - 5.3e-06 26.2 9.9 5.3e-06 26.2 6.9 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sas10_Utp3 PF04000.10 EMG50295.1 - 0.045 13.9 0.5 0.19 11.9 0.1 2.3 2 0 0 2 2 2 0 Sas10/Utp3/C1D family Cyclophil_like PF04126.8 EMG50295.1 - 0.11 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Cyclophilin-like Dickkopf_N PF04706.7 EMG50295.1 - 0.73 10.0 8.9 1.7 8.8 6.2 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Zn_clus PF00172.13 EMG50296.1 - 2.2e-05 24.2 6.8 4.1e-05 23.3 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_8 PF13855.1 EMG50298.1 - 4.2e-08 32.8 16.7 1.8e-05 24.3 0.0 7.2 6 1 1 7 7 7 2 Leucine rich repeat FNIP PF05725.7 EMG50298.1 - 0.0075 16.1 15.0 2.8 7.9 0.1 6.6 7 1 1 8 8 8 2 FNIP Repeat LRR_6 PF13516.1 EMG50298.1 - 0.029 14.3 15.6 2.6 8.3 0.1 7.3 9 0 0 9 9 9 0 Leucine Rich repeat LRR_4 PF12799.2 EMG50298.1 - 0.031 13.8 37.1 0.048 13.3 0.0 8.5 6 4 4 10 10 10 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EMG50298.1 - 0.18 12.1 21.3 6.8 7.3 0.0 10.2 13 0 0 13 13 13 0 Leucine rich repeat Pkinase PF00069.20 EMG50299.1 - 4.1e-56 190.0 0.0 1.5e-55 188.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50299.1 - 6.9e-25 87.5 0.0 2.7e-23 82.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG50299.1 - 0.00023 20.2 0.0 0.00043 19.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMG50299.1 - 0.0046 16.0 0.0 0.0069 15.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YodA PF09223.6 EMG50299.1 - 0.037 13.6 0.6 0.22 11.1 0.2 2.0 1 1 0 2 2 2 0 YodA lipocalin-like domain APH PF01636.18 EMG50299.1 - 0.045 13.4 0.0 0.12 12.0 0.0 1.5 1 1 0 2 2 2 0 Phosphotransferase enzyme family UPF0220 PF05255.6 EMG50300.1 - 8.8e-71 236.5 5.6 9.7e-71 236.3 3.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF3169 PF11368.3 EMG50300.1 - 0.93 8.6 4.0 0.31 10.2 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) WD40 PF00400.27 EMG50301.1 - 1.5e-45 151.5 14.8 2e-09 36.9 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EMG50301.1 - 1.4e-07 30.0 2.9 0.044 11.9 0.4 4.5 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMG50301.1 - 6.8e-05 21.7 8.7 0.2 10.3 1.1 4.7 1 1 3 4 4 4 4 Nup133 N terminal like PQQ_2 PF13360.1 EMG50301.1 - 0.00087 18.8 0.2 0.016 14.6 0.0 2.6 2 1 1 3 3 3 1 PQQ-like domain DUF3312 PF11768.3 EMG50301.1 - 0.0015 16.8 0.2 0.026 12.7 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3312) Utp8 PF10395.4 EMG50301.1 - 0.0022 16.3 0.5 0.017 13.4 0.1 2.4 2 1 0 3 3 3 1 Utp8 family Cytochrom_D1 PF02239.11 EMG50301.1 - 0.0039 15.5 0.0 0.16 10.2 0.0 2.7 3 0 0 3 3 3 1 Cytochrome D1 heme domain USP7_C2 PF14533.1 EMG50301.1 - 0.017 14.5 0.0 13 5.1 0.0 3.4 3 1 0 3 3 3 0 Ubiquitin-specific protease C-terminal IKI3 PF04762.7 EMG50301.1 - 0.023 12.5 0.0 0.26 9.0 0.0 2.0 1 1 0 2 2 2 0 IKI3 family Pkinase PF00069.20 EMG50302.1 - 2e-68 230.3 0.1 2e-68 230.3 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50302.1 - 9.8e-47 159.1 0.0 1.9e-46 158.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG50302.1 - 1.9e-08 33.6 0.0 5.4e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Antimicrobial19 PF08225.6 EMG50303.1 - 0.28 10.6 5.5 1.3 8.5 0.0 2.8 2 0 0 2 2 2 0 Pseudin antimicrobial peptide DUF745 PF05335.8 EMG50303.1 - 0.35 10.3 2.0 0.98 8.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF745) RhoGAP PF00620.22 EMG50304.1 - 0.00013 21.6 4.3 0.00019 21.0 0.1 3.0 3 0 0 3 3 3 1 RhoGAP domain TAFH PF07531.9 EMG50304.1 - 0.028 14.0 3.8 0.044 13.4 0.1 3.0 3 0 0 3 3 3 0 NHR1 homology to TAF CENP-O PF09496.5 EMG50305.1 - 9e-20 70.7 1.0 2.2e-19 69.4 0.1 2.0 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component APG6 PF04111.7 EMG50305.1 - 0.05 12.6 2.4 0.8 8.6 0.2 2.5 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF972 PF06156.8 EMG50305.1 - 0.21 11.9 3.0 4.5 7.6 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 EMG50305.1 - 0.53 9.8 4.4 0.35 10.3 1.4 2.0 2 0 0 2 2 2 0 Septum formation initiator Kinetocho_Slk19 PF12709.2 EMG50305.1 - 0.54 10.3 3.8 0.48 10.5 0.9 2.2 2 0 0 2 2 2 0 Central kinetochore-associated TBPIP PF07106.8 EMG50305.1 - 0.74 9.3 6.5 0.18 11.3 1.0 2.2 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DASH_Dad3 PF08656.5 EMG50305.1 - 1.1 8.9 4.3 0.41 10.3 0.9 1.8 2 0 0 2 2 2 0 DASH complex subunit Dad3 CENP-F_leu_zip PF10473.4 EMG50305.1 - 1.3 8.8 7.7 0.067 13.0 1.2 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nsp1_C PF05064.8 EMG50305.1 - 2.5 7.7 5.7 1.5 8.5 0.9 2.5 3 0 0 3 3 3 0 Nsp1-like C-terminal region FlaC_arch PF05377.6 EMG50305.1 - 4.7 7.1 7.7 3.8 7.4 2.8 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Clathrin PF00637.15 EMG50306.1 - 5.6e-198 648.4 55.1 5.8e-33 113.4 1.3 8.6 8 1 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EMG50306.1 - 7.2e-26 89.8 1.2 7.2e-26 89.8 0.8 2.3 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 EMG50306.1 - 1.3e-14 53.3 8.5 0.026 14.8 0.0 7.2 7 0 0 7 7 7 3 Clathrin propeller repeat TPR_2 PF07719.12 EMG50306.1 - 1.2e-06 27.9 3.3 0.89 9.6 0.0 7.6 7 1 1 8 8 8 1 Tetratricopeptide repeat Clathrin-link PF09268.5 EMG50306.1 - 2.7e-05 23.1 0.2 8.9e-05 21.4 0.2 2.0 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_7 PF13176.1 EMG50306.1 - 3e-05 23.4 3.2 22 5.1 0.0 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMG50306.1 - 6.2e-05 22.8 0.9 2.6 8.0 0.0 6.5 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.1 EMG50306.1 - 0.0031 17.1 9.6 2.4 7.8 0.4 7.2 7 1 0 7 7 7 1 TPR repeat TPR_14 PF13428.1 EMG50306.1 - 0.0043 17.5 0.1 93 4.0 0.0 6.6 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMG50306.1 - 0.082 13.1 2.9 1.7 9.0 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EMG50306.1 - 0.083 13.2 4.3 32 4.9 0.0 6.2 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMG50306.1 - 3.4 7.4 19.5 4.3 7.1 0.0 7.2 10 0 0 10 10 10 0 Tetratricopeptide repeat adh_short PF00106.20 EMG50307.1 - 6.4e-23 81.4 0.0 8e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMG50307.1 - 3.7e-22 79.2 0.0 4.4e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMG50307.1 - 8.6e-09 35.3 0.0 1.2e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EMG50307.1 - 0.03 13.4 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ATP-synt_Eps PF04627.8 EMG50308.1 - 1.6e-17 62.7 0.1 1.8e-17 62.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain T2SF PF00482.18 EMG50308.1 - 0.14 12.0 0.1 0.17 11.7 0.1 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F DNA_pol_phi PF04931.8 EMG50309.1 - 9.8e-55 185.6 71.6 2.2e-36 125.0 35.3 3.3 1 1 1 2 2 2 2 DNA polymerase phi WD40 PF00400.27 EMG50310.1 - 0.00013 21.7 1.3 0.00013 21.7 0.9 3.4 4 0 0 4 4 4 1 WD domain, G-beta repeat BBS2_Mid PF14783.1 EMG50310.1 - 0.03 14.1 0.2 3.3 7.5 0.0 2.7 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region HALZ PF02183.13 EMG50311.1 - 0.66 9.7 8.4 18 5.1 0.1 3.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.4 EMG50311.1 - 1.2 8.9 22.9 0.41 10.4 7.3 3.1 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.7 EMG50311.1 - 1.5 9.2 11.3 6.5 7.2 1.7 3.8 3 0 0 3 3 3 0 SlyX Cep57_MT_bd PF06657.8 EMG50311.1 - 1.7 8.6 12.2 0.81 9.6 3.5 3.6 1 1 3 4 4 4 0 Centrosome microtubule-binding domain of Cep57 IncA PF04156.9 EMG50311.1 - 2.5 7.6 25.1 1.8e+02 1.5 17.4 2.5 1 1 0 1 1 1 0 IncA protein DEAD PF00270.24 EMG50312.1 - 1.5e-23 83.1 0.1 1.3e-22 80.1 0.0 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG50312.1 - 5.5e-14 51.7 0.0 1.6e-13 50.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMG50312.1 - 1.1e-07 31.8 0.1 1.9e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EMG50312.1 - 0.08 13.0 0.1 5.6 7.1 0.0 3.4 4 0 0 4 4 4 0 AAA domain DAP3 PF10236.4 EMG50313.1 - 8.6e-68 228.5 2.1 1.3e-67 227.8 1.5 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 DUF1877 PF08974.5 EMG50313.1 - 0.0023 17.5 0.2 0.0064 16.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1877) MobB PF03205.9 EMG50313.1 - 0.0099 15.5 0.3 0.06 13.0 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EMG50313.1 - 0.013 15.4 1.7 0.032 14.1 0.4 2.4 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EMG50313.1 - 0.12 12.3 0.0 0.46 10.4 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 EMG50313.1 - 1 9.7 5.9 0.94 9.7 1.1 2.7 2 1 1 3 3 3 0 AAA domain UPF0113 PF03657.8 EMG50314.1 - 1.1e-09 38.1 0.0 1.5e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PseudoU_synth_1 PF01416.15 EMG50315.1 - 2.1e-26 92.4 0.0 2.6e-12 47.0 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase Pkinase PF00069.20 EMG50316.1 - 4.8e-39 134.0 1.6 6.8e-39 133.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50316.1 - 1.2e-14 53.9 0.1 2.5e-14 52.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EMG50316.1 - 1.6e-06 28.0 2.3 0.0032 17.2 0.0 3.2 3 0 0 3 3 3 2 Phosphotransferase enzyme family Mitofilin PF09731.4 EMG50316.1 - 3.2 6.3 18.2 4.4 5.8 12.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein WD40 PF00400.27 EMG50317.1 - 5.7e-09 35.5 3.6 6e-05 22.7 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat PspB PF06667.7 EMG50318.1 - 0.13 12.2 0.5 0.42 10.5 0.3 1.8 1 0 0 1 1 1 0 Phage shock protein B DUF3106 PF11304.3 EMG50318.1 - 0.64 10.4 4.7 1.8 9.0 1.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) Fib_alpha PF08702.5 EMG50318.1 - 1.9 8.5 18.7 0.95 9.5 1.0 3.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.1 EMG50318.1 - 3.7 7.9 12.7 1.2 9.4 2.6 3.1 1 1 2 3 3 3 0 Snapin/Pallidin RRM_6 PF14259.1 EMG50319.1 - 9.8e-13 47.8 0.1 2.1e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMG50319.1 - 9.7e-12 44.3 1.4 4.7e-11 42.1 0.1 2.6 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG50319.1 - 2.8e-05 23.8 0.4 0.00016 21.4 0.0 2.3 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EMG50319.1 - 0.0093 15.6 1.9 0.051 13.3 0.1 2.5 2 1 0 2 2 2 1 Limkain b1 CBS PF00571.23 EMG50320.1 - 1.1e-31 108.2 2.0 1.2e-11 44.1 0.1 4.9 4 1 1 5 5 5 4 CBS domain DUF2733 PF10813.3 EMG50320.1 - 0.032 13.7 0.1 0.17 11.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) HTH_9 PF08221.6 EMG50320.1 - 0.11 12.4 0.8 1.3 8.9 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain OPT PF03169.10 EMG50321.1 - 1.1e-149 499.7 21.0 1.3e-149 499.5 14.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein KH_1 PF00013.24 EMG50322.1 - 1.8e-32 110.7 5.0 1.3e-12 47.1 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EMG50322.1 - 3.4e-23 80.8 6.3 3.1e-09 36.2 0.3 3.8 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EMG50322.1 - 4.6e-09 35.7 3.9 0.0083 15.6 0.0 3.6 4 0 0 4 4 4 3 KH domain KH_4 PF13083.1 EMG50322.1 - 2.4e-05 23.8 0.3 1.8 8.2 0.0 3.8 4 0 0 4 4 4 3 KH domain BCNT PF07572.7 EMG50323.1 - 1.1e-24 86.1 3.0 2.7e-24 84.8 2.1 1.7 1 0 0 1 1 1 1 Bucentaur or craniofacial development Peptidase_M49 PF03571.10 EMG50324.1 - 1.9e-222 739.2 0.5 3e-222 738.5 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M49 ABC_membrane PF00664.18 EMG50324.1 - 1.3e-43 149.3 8.3 2.1e-43 148.7 5.7 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EMG50324.1 - 4.2e-29 101.5 2.5 4.4e-29 101.5 0.0 2.5 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EMG50324.1 - 4.4e-07 29.3 0.0 7e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EMG50324.1 - 5.1e-05 23.4 1.1 0.0024 18.0 0.3 3.3 2 1 0 2 2 2 1 AAA domain ABC_ATPase PF09818.4 EMG50324.1 - 0.00042 19.0 0.2 0.0008 18.1 0.2 1.4 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_16 PF13191.1 EMG50324.1 - 0.0018 18.3 0.4 0.014 15.3 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EMG50324.1 - 0.012 16.4 1.4 0.032 15.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EMG50324.1 - 0.038 13.4 0.0 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mt_ATP-synt_D PF05873.7 EMG50325.1 - 0.02 14.5 0.0 0.021 14.4 0.0 1.1 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) HTH_7 PF02796.10 EMG50325.1 - 0.11 12.4 0.3 0.99 9.3 0.0 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase GMC_oxred_N PF00732.14 EMG50326.1 - 9.2e-25 87.3 0.2 1.1e-24 87.1 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EMG50326.1 - 5.4e-05 22.2 0.7 6.6e-05 21.9 0.5 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMG50326.1 - 0.00013 21.9 0.2 0.00025 21.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMG50326.1 - 0.015 15.1 0.4 0.022 14.6 0.3 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMG50326.1 - 0.064 12.1 0.2 0.085 11.7 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Stirrup PF09061.1 EMG50326.1 - 0.11 12.3 0.1 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Stirrup FAD_binding_3 PF01494.14 EMG50326.1 - 0.12 11.3 0.1 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain GMC_oxred_C PF05199.8 EMG50327.1 - 1.4e-24 87.0 0.0 1.8e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase WD40 PF00400.27 EMG50328.1 - 4.5e-06 26.3 0.0 3.8e-05 23.3 0.0 2.4 3 0 0 3 3 3 1 WD domain, G-beta repeat MCPsignal PF00015.16 EMG50328.1 - 0.0045 16.5 10.9 0.0045 16.5 7.5 3.9 2 1 1 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.6 EMG50328.1 - 0.026 14.3 6.6 0.69 9.8 1.7 4.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF445 PF04286.7 EMG50328.1 - 0.41 10.1 30.2 0.72 9.3 7.6 4.0 2 1 1 3 3 3 0 Protein of unknown function (DUF445) Tweety PF04906.8 EMG50328.1 - 3.4 5.9 5.4 7.1 4.9 0.5 2.2 2 0 0 2 2 2 0 Tweety DUF883 PF05957.8 EMG50328.1 - 9 6.7 8.6 1.6 9.1 0.3 3.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) SAP PF02037.22 EMG50329.1 - 5.5e-08 32.1 0.0 2.6e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 SAP domain zf-RING_2 PF13639.1 EMG50329.1 - 1e-07 31.6 17.6 2.3e-07 30.4 8.3 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EMG50329.1 - 2.9e-07 30.0 13.9 2.9e-07 30.0 9.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMG50329.1 - 6.5e-07 29.2 12.9 6.5e-07 29.2 8.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMG50329.1 - 9.5e-07 28.5 8.8 9.5e-07 28.5 6.1 2.4 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EMG50329.1 - 3.9e-06 26.5 8.7 4.2e-06 26.4 3.6 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 EMG50329.1 - 6.6e-06 25.7 15.9 0.00013 21.5 8.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMG50329.1 - 0.00056 19.5 21.5 0.00066 19.3 11.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain U-box PF04564.10 EMG50329.1 - 0.02 14.8 0.1 0.12 12.3 0.0 2.3 2 0 0 2 2 2 0 U-box domain zf-RING_UBOX PF13445.1 EMG50329.1 - 0.033 13.8 16.8 0.23 11.1 7.6 3.5 2 1 1 3 3 3 0 RING-type zinc-finger Pex14_N PF04695.8 EMG50329.1 - 0.23 11.4 3.1 0.47 10.4 2.1 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-rbx1 PF12678.2 EMG50329.1 - 2.4 8.3 17.6 0.37 10.9 6.7 2.7 2 2 0 2 2 2 0 RING-H2 zinc finger DUF2360 PF10152.4 EMG50329.1 - 4.4 7.5 13.2 28 4.9 9.1 2.1 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Prok-RING_4 PF14447.1 EMG50329.1 - 4.6 6.8 11.1 21 4.7 5.5 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF605 PF04652.11 EMG50329.1 - 4.6 6.5 14.6 6.6 6.0 10.1 1.2 1 0 0 1 1 1 0 Vta1 like DZR PF12773.2 EMG50329.1 - 5.1 7.0 10.9 8.3 6.3 4.5 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-MIZ PF02891.15 EMG50329.1 - 5.2 6.6 16.0 41 3.7 0.0 2.5 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Form_Nir_trans PF01226.12 EMG50330.1 - 8.1e-64 214.9 27.5 9.6e-64 214.6 19.0 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Phos_pyr_kin PF08543.7 EMG50331.1 - 6.1e-10 38.7 0.0 9.2e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EMG50331.1 - 5.9e-08 32.2 0.0 7.6e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase SUR7 PF06687.7 EMG50332.1 - 1.4e-33 116.2 13.6 1.7e-33 115.9 9.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 EMG50332.1 - 4.5e-05 23.4 9.5 4.5e-05 23.4 6.6 1.5 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Claudin_2 PF13903.1 EMG50332.1 - 0.00021 21.0 7.3 0.00021 21.0 5.0 2.0 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Tetraspannin PF00335.15 EMG50332.1 - 0.98 8.6 17.0 19 4.4 11.8 2.4 1 1 0 1 1 1 0 Tetraspanin family Cytochrom_B_N PF00033.14 EMG50332.1 - 1.8 7.8 11.6 10 5.3 6.8 2.6 2 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Lipase_3 PF01764.20 EMG50333.1 - 3.6e-07 29.8 0.0 7.2e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.7 EMG50333.1 - 0.022 14.4 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.2 EMG50333.1 - 0.043 13.5 0.0 0.21 11.3 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EMG50333.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Fmp27 PF10344.4 EMG50334.1 - 6.9e-183 609.6 37.6 6.9e-183 609.6 26.0 1.6 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Fmp27_WPPW PF10359.4 EMG50334.1 - 1.1e-87 294.5 16.7 2.2e-87 293.4 11.6 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 EMG50334.1 - 4.8e-55 185.7 0.1 1.6e-54 184.0 0.0 2.0 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EMG50334.1 - 3e-53 179.7 0.4 1.5e-52 177.5 0.3 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EMG50334.1 - 8.4e-32 109.6 0.6 4.4e-31 107.3 0.1 2.7 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Tropomyosin_1 PF12718.2 EMG50334.1 - 0.048 13.4 0.3 0.13 12.1 0.2 1.7 1 0 0 1 1 1 0 Tropomyosin like Ribosomal_L32e PF01655.13 EMG50335.1 - 2.2e-46 156.4 2.0 2.7e-46 156.1 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 DUF3437 PF11919.3 EMG50335.1 - 0.023 14.3 0.1 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) tRNA-synt_1e PF01406.14 EMG50335.1 - 0.028 13.5 0.2 0.046 12.8 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Pkinase PF00069.20 EMG50336.1 - 1.1e-45 155.8 0.0 1.6e-45 155.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50336.1 - 1e-21 77.1 0.0 1.7e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG50336.1 - 2.6e-06 26.6 0.0 5.2e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMG50336.1 - 0.024 13.7 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EMG50336.1 - 0.038 13.3 0.0 0.083 12.2 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL ChAPs PF09295.5 EMG50336.1 - 0.041 12.6 0.5 0.079 11.7 0.3 1.4 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Rubella_Capsid PF05750.6 EMG50336.1 - 1.2 8.4 11.7 2.7 7.3 8.1 1.5 1 0 0 1 1 1 0 Rubella capsid protein SDA1 PF05285.7 EMG50336.1 - 9.9 5.3 15.6 9.6 5.3 0.1 2.2 2 0 0 2 2 2 0 SDA1 MFS_1 PF07690.11 EMG50337.1 - 5.1e-06 25.4 18.2 3.7e-05 22.6 10.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMG50337.1 - 1.5e-05 23.6 8.5 2.3e-05 22.9 5.9 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein Apt1 PF10351.4 EMG50338.1 - 3.1e-113 379.0 19.3 3.9e-113 378.7 13.4 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain DNA_pol_A PF00476.15 EMG50339.1 - 4.9e-89 298.6 0.0 9.2e-89 297.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 EMG50339.1 - 0.024 14.1 0.1 1.4 8.3 0.0 2.6 2 0 0 2 2 2 0 3'-5' exonuclease CDC45 PF02724.9 EMG50340.1 - 0.0025 15.9 16.8 0.0031 15.6 11.6 1.1 1 0 0 1 1 1 1 CDC45-like protein SAPS PF04499.10 EMG50340.1 - 0.0068 15.0 1.0 0.0081 14.8 0.7 1.2 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Nop14 PF04147.7 EMG50340.1 - 0.026 12.4 32.1 0.034 12.0 22.3 1.1 1 0 0 1 1 1 0 Nop14-like family Ycf1 PF05758.7 EMG50340.1 - 0.045 11.4 4.5 0.052 11.2 3.1 1.2 1 0 0 1 1 1 0 Ycf1 CENP-T PF15511.1 EMG50340.1 - 0.12 11.5 18.4 0.16 11.1 12.8 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T NifU PF01106.12 EMG50340.1 - 0.16 11.8 0.1 0.38 10.5 0.1 1.6 1 0 0 1 1 1 0 NifU-like domain Vfa1 PF08432.5 EMG50340.1 - 0.19 11.7 12.3 0.29 11.1 8.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Daxx PF03344.10 EMG50340.1 - 0.2 10.0 27.4 0.25 9.7 19.0 1.1 1 0 0 1 1 1 0 Daxx Family CobT PF06213.7 EMG50340.1 - 0.27 10.3 27.7 0.36 9.9 19.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.5 EMG50340.1 - 0.46 9.5 23.2 0.59 9.1 16.1 1.1 1 0 0 1 1 1 0 BUD22 Spore_coat_CotO PF14153.1 EMG50340.1 - 0.86 9.0 11.3 1.1 8.6 7.9 1.2 1 0 0 1 1 1 0 Spore coat protein CotO SDA1 PF05285.7 EMG50340.1 - 1.3 8.2 31.8 1.8 7.7 22.0 1.1 1 0 0 1 1 1 0 SDA1 Tim54 PF11711.3 EMG50340.1 - 1.5 7.3 6.9 2.4 6.6 4.8 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF1510 PF07423.6 EMG50340.1 - 1.6 8.0 26.1 0.19 11.0 14.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Nop53 PF07767.6 EMG50340.1 - 1.6 7.6 17.6 2.1 7.2 12.2 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PBP_sp32 PF07222.7 EMG50340.1 - 2.6 7.1 15.0 4.2 6.4 10.4 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 SDA1 PF05285.7 EMG50341.1 - 9.5 5.3 32.5 0.14 11.3 3.5 2.5 2 0 0 2 2 2 0 SDA1 PWWP PF00855.12 EMG50342.1 - 1.4e-13 50.8 0.0 1.4e-13 50.8 0.0 3.3 3 1 0 3 3 3 1 PWWP domain DUF4582 PF15189.1 EMG50342.1 - 0.0047 16.1 0.1 0.011 14.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4582) Med26 PF08711.6 EMG50342.1 - 0.035 13.6 0.1 0.16 11.4 0.1 2.2 1 1 0 1 1 1 0 TFIIS helical bundle-like domain DUF3439 PF11921.3 EMG50342.1 - 0.056 13.1 2.4 0.14 11.9 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) YL1 PF05764.8 EMG50342.1 - 5 6.6 38.7 0.39 10.2 23.2 1.7 2 0 0 2 2 2 0 YL1 nuclear protein eIF-5a PF01287.15 EMG50343.1 - 1.5e-28 98.5 0.5 2.3e-28 97.9 0.4 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EMG50343.1 - 0.00015 21.3 0.6 0.00032 20.2 0.4 1.6 1 0 0 1 1 1 1 KOW motif TcdB_toxin_midN PF12256.3 EMG50343.1 - 0.01 15.2 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region EFP_N PF08207.7 EMG50343.1 - 0.026 14.3 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain zf-RING_2 PF13639.1 EMG50344.1 - 2.5e-13 49.5 6.9 4.2e-13 48.8 4.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMG50344.1 - 6e-08 32.6 4.1 1.4e-07 31.5 2.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EMG50344.1 - 7.5e-07 28.7 5.0 1.2e-06 28.1 3.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMG50344.1 - 1.3e-06 27.9 6.0 2.4e-06 27.1 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMG50344.1 - 1.3e-06 28.1 1.8 2.7e-06 27.1 1.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EMG50344.1 - 5.4e-06 26.3 7.7 8.7e-06 25.6 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMG50344.1 - 0.00022 20.8 4.7 0.00034 20.2 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMG50344.1 - 0.0025 17.5 4.8 0.0059 16.3 3.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger FYDLN_acid PF09538.5 EMG50344.1 - 0.0083 16.6 3.1 0.0083 16.6 2.1 3.6 3 1 0 3 3 2 1 Protein of unknown function (FYDLN_acid) PHD PF00628.24 EMG50344.1 - 0.032 13.9 6.4 0.056 13.1 4.4 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 EMG50344.1 - 0.057 13.0 6.1 0.11 12.1 4.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.1 EMG50344.1 - 0.12 12.0 6.0 0.43 10.3 4.1 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 RINGv PF12906.2 EMG50344.1 - 0.18 11.9 7.3 0.33 11.0 5.1 1.5 1 0 0 1 1 1 0 RING-variant domain SKG6 PF08693.5 EMG50344.1 - 0.39 10.0 1.2 1.1 8.6 0.8 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FANCL_C PF11793.3 EMG50344.1 - 0.43 10.5 3.9 1.5 8.8 2.7 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Rtf2 PF04641.7 EMG50344.1 - 0.66 9.1 7.6 0.07 12.3 1.2 2.1 2 1 0 2 2 2 0 Rtf2 RING-finger zf-C3HC4_4 PF15227.1 EMG50344.1 - 1.5 8.7 6.3 3 7.7 4.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ctr PF04145.10 EMG50344.1 - 5.2 7.1 5.4 18 5.3 0.0 3.3 3 1 1 4 4 4 0 Ctr copper transporter family RRM_6 PF14259.1 EMG50345.1 - 4.6e-11 42.5 0.0 7.1e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMG50345.1 - 3.2e-10 39.4 0.0 6.1e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_S49_N PF08496.5 EMG50345.1 - 0.34 10.6 1.5 0.52 10.0 1.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Rox3 PF08633.5 EMG50346.1 - 6.2e-27 95.1 0.1 1.4e-23 84.2 0.0 2.1 1 1 1 2 2 2 2 Rox3 mediator complex subunit Gly_transf_sug PF04488.10 EMG50347.1 - 2.9e-13 50.0 0.0 1.1e-12 48.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EMG50347.1 - 0.016 13.7 1.1 0.2 10.1 0.0 2.3 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain KIAA1430 PF13879.1 EMG50347.1 - 0.022 15.1 0.1 0.048 14.0 0.1 1.6 1 0 0 1 1 1 0 KIAA1430 homologue Abhydro_lipase PF04083.11 EMG50348.1 - 0.11 11.9 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region zf-H2C2_2 PF13465.1 EMG50349.1 - 0.0001 22.3 16.0 0.00097 19.3 4.0 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMG50349.1 - 0.00018 21.6 17.9 0.049 14.0 1.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMG50349.1 - 0.046 14.0 18.8 0.89 10.0 2.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger MFS_1 PF07690.11 EMG50351.1 - 2.6e-39 134.9 36.3 8.6e-37 126.6 27.4 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG50351.1 - 3.4e-14 52.2 7.2 3.4e-14 52.2 5.0 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EMG50351.1 - 2.2e-09 36.0 26.8 3.8e-09 35.2 18.6 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EMG50351.1 - 0.11 10.5 22.6 0.058 11.4 3.3 3.4 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PIRT PF15099.1 EMG50351.1 - 0.32 10.2 3.7 0.32 10.2 0.1 2.6 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Grp1_Fun34_YaaH PF01184.14 EMG50352.1 - 2.3e-79 265.5 22.7 2.7e-79 265.3 15.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Oxidored_FMN PF00724.15 EMG50353.1 - 1.9e-100 336.2 0.0 2.4e-100 335.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family HH_signal PF01085.13 EMG50353.1 - 0.066 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain Grp1_Fun34_YaaH PF01184.14 EMG50354.1 - 3.2e-75 252.0 22.6 3.8e-75 251.7 15.7 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Grp1_Fun34_YaaH PF01184.14 EMG50355.1 - 6.6e-70 234.6 18.8 8.3e-70 234.3 13.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Oxidored_FMN PF00724.15 EMG50356.1 - 3e-113 378.2 0.0 3.5e-113 378.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF3890 PF13029.1 EMG50357.1 - 5.5 7.1 8.1 1 9.4 0.8 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3890) DnaJ PF00226.26 EMG50358.1 - 4.7e-28 96.7 1.2 7.7e-28 96.0 0.8 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EMG50358.1 - 2.7e-15 56.1 19.4 4.6e-15 55.4 13.4 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 EMG50358.1 - 3.3e-07 30.1 0.7 5.4e-05 23.0 0.0 3.0 3 0 0 3 3 3 1 DnaJ C terminal domain HypA PF01155.14 EMG50358.1 - 0.056 13.1 5.7 0.21 11.2 0.5 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family PIG-X PF08320.7 EMG50359.1 - 6.2e-37 126.8 0.1 1.3e-36 125.8 0.0 1.6 1 0 0 1 1 1 1 PIG-X / PBN1 Mog1 PF04603.7 EMG50360.1 - 4e-15 56.0 0.4 6e-14 52.1 0.3 2.1 1 1 0 1 1 1 1 Ran-interacting Mog1 protein Flocculin_t3 PF13928.1 EMG50361.1 - 2.2e-08 34.1 28.5 2.2e-08 34.1 19.7 5.5 3 1 0 3 3 3 1 Flocculin type 3 repeat AA_permease_2 PF13520.1 EMG50362.1 - 1.4e-59 201.7 40.5 1.7e-59 201.4 28.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMG50362.1 - 2.5e-15 55.8 37.9 3.3e-15 55.3 26.3 1.0 1 0 0 1 1 1 1 Amino acid permease Pam17 PF08566.5 EMG50362.1 - 0.11 12.2 0.1 0.3 10.7 0.1 1.8 1 1 0 1 1 1 0 Mitochondrial import protein Pam17 DEAD PF00270.24 EMG50363.1 - 4.7e-44 149.8 0.0 3.3e-43 147.0 0.0 2.3 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG50363.1 - 4.3e-22 77.7 0.2 1.8e-21 75.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EMG50363.1 - 1.4e-19 69.6 7.9 1.4e-19 69.6 5.5 2.6 2 0 0 2 2 2 1 DBP10CT (NUC160) domain Ribosomal_S19e PF01090.14 EMG50364.1 - 4.3e-52 175.2 0.0 5e-52 175.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Channel_Tsx PF03502.8 EMG50364.1 - 0.092 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Nucleoside-specific channel-forming protein, Tsx Peptidase_C14 PF00656.17 EMG50365.1 - 1.5e-70 237.7 0.1 2.1e-70 237.2 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Ras PF00071.17 EMG50366.1 - 3.9e-46 156.3 0.8 6.8e-46 155.5 0.5 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EMG50366.1 - 2.2e-13 50.7 0.1 8.5e-11 42.3 0.0 2.2 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EMG50366.1 - 1.4e-05 24.9 0.2 2.1e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMG50366.1 - 0.00084 18.8 0.3 0.21 11.0 0.2 2.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EMG50366.1 - 0.0017 17.6 0.1 0.0062 15.7 0.1 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMG50366.1 - 0.0025 17.0 0.0 0.0042 16.3 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EMG50366.1 - 0.0033 16.7 0.1 2.1 7.6 0.0 2.3 2 1 0 2 2 2 2 Ferrous iron transport protein B AAA_14 PF13173.1 EMG50366.1 - 0.02 14.7 1.5 0.024 14.5 0.1 1.8 2 1 0 2 2 2 0 AAA domain Zn_clus PF00172.13 EMG50367.1 - 2.6e-09 36.8 9.3 4.8e-09 35.9 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_E2-like PF04497.7 EMG50367.1 - 0.18 9.8 1.4 0.31 9.0 1.0 1.3 1 0 0 1 1 1 0 Poxviridae protein FAD-oxidase_C PF02913.14 EMG50368.1 - 2.2e-57 194.2 0.0 2.9e-57 193.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EMG50368.1 - 4e-35 120.3 0.0 8.1e-35 119.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Peptidase_M14 PF00246.19 EMG50369.1 - 5.9e-58 196.6 0.0 8.7e-58 196.1 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase F-box PF00646.28 EMG50370.1 - 0.00023 20.7 0.2 0.00051 19.6 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMG50370.1 - 0.0098 15.6 0.1 0.0098 15.6 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 EMG50370.1 - 0.032 13.9 0.1 0.061 13.0 0.1 1.4 1 0 0 1 1 1 0 F-box-like domain Endosulfine PF04667.12 EMG50371.1 - 4.9e-28 96.9 1.2 6.8e-28 96.4 0.8 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region S-antigen PF05756.6 EMG50371.1 - 0.015 15.2 0.1 0.036 14.0 0.1 1.6 1 0 0 1 1 1 0 S-antigen protein Autophagy_act_C PF03987.10 EMG50372.1 - 3e-12 46.5 1.4 7.6e-12 45.2 1.0 1.7 1 1 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Thi4 PF01946.12 EMG50374.1 - 5.2e-97 323.4 0.0 6.3e-97 323.1 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EMG50374.1 - 2.9e-09 36.3 0.2 1.2e-07 31.0 0.2 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMG50374.1 - 9.4e-07 28.9 0.3 1.8e-06 27.9 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMG50374.1 - 1e-06 28.9 0.6 0.0018 18.4 0.1 1.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMG50374.1 - 1e-06 27.9 0.2 6e-06 25.4 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EMG50374.1 - 1.6e-06 27.2 0.9 5.8e-05 22.1 0.5 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EMG50374.1 - 2.3e-05 24.3 0.1 5.6e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EMG50374.1 - 0.00037 19.7 0.0 0.00061 18.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EMG50374.1 - 0.00063 18.7 0.2 0.0011 17.8 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EMG50374.1 - 0.00067 19.4 0.6 0.0026 17.5 0.0 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EMG50374.1 - 0.0011 17.5 0.3 0.0019 16.7 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 EMG50374.1 - 0.0022 16.6 0.2 0.0037 15.9 0.1 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Shikimate_DH PF01488.15 EMG50374.1 - 0.083 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UPF0020 PF01170.13 EMG50375.1 - 3.9e-14 52.6 0.0 8.3e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EMG50375.1 - 2.2e-10 40.5 0.0 3.8e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 EMG50375.1 - 0.00044 19.8 0.0 0.012 15.0 0.0 2.4 2 1 0 2 2 2 1 DNA methylase N6_Mtase PF02384.11 EMG50375.1 - 0.0013 17.8 0.0 0.0092 15.0 0.0 2.4 2 1 0 2 2 2 1 N-6 DNA Methylase Cons_hypoth95 PF03602.10 EMG50375.1 - 0.016 14.5 0.0 0.098 12.0 0.0 2.2 1 1 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_15 PF09445.5 EMG50375.1 - 0.046 13.2 0.2 0.12 11.9 0.1 1.7 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 EMG50375.1 - 0.074 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein MFS_1 PF07690.11 EMG50376.1 - 8.2e-05 21.4 8.9 0.00069 18.4 5.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Bax1-I PF01027.15 EMG50376.1 - 1 8.8 12.6 1.4 8.4 8.2 1.5 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Flocculin_t3 PF13928.1 EMG50377.1 - 3.4e-16 59.0 60.1 2e-09 37.4 12.5 9.5 5 2 1 6 6 6 2 Flocculin type 3 repeat MFS_1 PF07690.11 EMG50378.1 - 2e-06 26.7 8.2 6.6e-05 21.7 6.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily HlyIII PF03006.15 EMG50378.1 - 0.073 12.4 4.5 0.095 12.0 3.1 1.2 1 0 0 1 1 1 0 Haemolysin-III related Apq12 PF12716.2 EMG50378.1 - 0.1 12.3 1.0 0.29 10.8 0.0 2.3 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis FtsX PF02687.16 EMG50378.1 - 0.48 10.1 10.3 36 4.1 7.1 2.3 1 1 0 1 1 1 0 FtsX-like permease family Tmemb_170 PF10190.4 EMG50378.1 - 0.75 9.8 4.4 0.38 10.8 1.0 2.0 1 1 1 2 2 2 0 Putative transmembrane protein 170 Flavi_NS4A PF01350.12 EMG50378.1 - 2 7.9 6.4 5.8 6.4 0.3 2.1 1 1 0 2 2 2 0 Flavivirus non-structural protein NS4A Bax1-I PF01027.15 EMG50378.1 - 2.1 7.9 13.2 7.1 6.1 9.1 1.7 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF4282 PF14110.1 EMG50378.1 - 5.1 7.3 7.1 1.9 8.7 0.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4282) DUF3533 PF12051.3 EMG50379.1 - 7.8e-130 433.0 22.2 1.1e-129 432.6 15.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) PDR_CDR PF06422.7 EMG50379.1 - 0.0038 16.8 0.2 0.0038 16.8 0.1 2.8 4 0 0 4 4 4 1 CDR ABC transporter SAGA-Tad1 PF12767.2 EMG50380.1 - 2.4e-56 191.1 5.7 2.4e-56 191.1 4.0 1.6 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Reo_sigmaC PF04582.7 EMG50381.1 - 0.015 14.4 0.9 5.5 6.0 1.1 2.8 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF4328 PF14219.1 EMG50382.1 - 0.12 11.6 0.5 0.3 10.3 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) MFS_1 PF07690.11 EMG50383.1 - 1.3e-26 93.2 68.9 2.6e-26 92.2 43.8 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Transp_cyt_pur PF02133.10 EMG50384.1 - 6.8e-146 486.2 31.2 7.9e-146 486.0 21.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Transp_cyt_pur PF02133.10 EMG50385.1 - 1.3e-146 488.6 28.6 1.5e-146 488.4 19.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Abhydrolase_6 PF12697.2 EMG50386.1 - 2.4e-15 57.0 0.0 6e-15 55.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMG50386.1 - 3.4e-11 43.1 0.0 8.6e-09 35.2 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMG50386.1 - 5.6e-05 22.9 0.0 0.0011 18.7 0.0 2.5 2 1 1 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EMG50386.1 - 0.0043 16.5 0.0 0.38 10.1 0.0 2.8 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Esterase PF00756.15 EMG50386.1 - 0.012 15.0 0.0 0.062 12.7 0.0 1.9 2 0 0 2 2 2 0 Putative esterase Ser_hydrolase PF06821.8 EMG50386.1 - 0.18 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase GCV_T PF01571.16 EMG50387.1 - 8.5e-05 22.0 0.0 0.34 10.2 0.0 2.4 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain S1-like PF14444.1 EMG50387.1 - 0.0057 16.3 0.2 0.36 10.5 0.0 2.5 2 0 0 2 2 2 1 S1-like GCV_T_C PF08669.6 EMG50387.1 - 0.042 13.8 0.0 0.087 12.8 0.0 1.7 1 1 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain PNP_UDP_1 PF01048.15 EMG50388.1 - 1.2e-45 155.3 0.0 1.4e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily WD40 PF00400.27 EMG50389.1 - 8.1e-28 95.2 15.3 7.6e-10 38.2 0.1 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat Kelch_6 PF13964.1 EMG50389.1 - 0.079 13.1 0.0 0.8 9.9 0.0 2.4 2 0 0 2 2 2 0 Kelch motif PG_binding_1 PF01471.13 EMG50390.1 - 0.088 12.7 0.6 0.3 11.1 0.0 2.2 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Methyltransf_31 PF13847.1 EMG50394.1 - 7.8e-13 48.2 0.5 3e-12 46.3 0.4 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMG50394.1 - 2.4e-12 46.8 0.0 3.8e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMG50394.1 - 1.5e-08 35.0 0.4 6.3e-08 32.9 0.3 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMG50394.1 - 2.5e-08 34.3 0.1 1.9e-07 31.4 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMG50394.1 - 0.0066 15.5 0.1 0.0096 15.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 EMG50394.1 - 0.011 15.1 0.0 2.9 7.2 0.0 2.7 2 1 1 3 3 3 0 Nodulation protein S (NodS) Zn_clus PF00172.13 EMG50396.1 - 2.6e-09 36.8 15.0 4.3e-09 36.1 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAF1_ABF1 PF04684.8 EMG50396.1 - 1.6 7.4 18.0 2.6 6.7 12.5 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Ammonium_transp PF00909.16 EMG50397.1 - 6.5e-106 354.1 26.7 7.7e-106 353.9 18.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family TPP_enzyme_N PF02776.13 EMG50398.1 - 2e-57 193.4 0.4 6.7e-57 191.7 0.1 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EMG50398.1 - 8.1e-50 168.3 1.7 2.6e-48 163.4 0.3 3.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMG50398.1 - 2.4e-40 137.4 0.6 1.9e-39 134.5 0.2 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 EMG50398.1 - 0.0031 17.0 0.1 0.0072 15.8 0.0 1.6 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg CO_dh PF02552.11 EMG50398.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit adh_short PF00106.20 EMG50399.1 - 7.3e-18 65.0 0.0 1e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMG50399.1 - 2.5e-09 37.0 0.0 3.4e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMG50399.1 - 0.00026 20.4 0.0 0.00041 19.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMG50399.1 - 0.0028 16.5 0.1 0.0037 16.2 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EMG50399.1 - 0.1 12.5 0.1 0.8 9.6 0.0 2.1 1 1 0 1 1 1 0 NADH(P)-binding Shikimate_DH PF01488.15 EMG50399.1 - 0.12 12.4 0.5 0.4 10.7 0.3 1.9 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.11 EMG50400.1 - 2.5e-35 121.8 38.2 2.5e-35 121.8 26.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMG50400.1 - 0.00093 17.5 4.6 0.00093 17.5 3.2 2.1 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Kri1_C PF12936.2 EMG50402.1 - 4.7e-33 112.9 6.4 4.7e-33 112.9 4.4 4.7 4 1 1 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.7 EMG50402.1 - 2e-19 69.7 16.3 2e-19 69.7 11.3 6.1 3 1 2 6 6 6 1 KRI1-like family DUF1249 PF06853.7 EMG50402.1 - 0.021 14.4 1.8 0.086 12.4 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1249) HTH_30 PF13556.1 EMG50402.1 - 0.051 13.1 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain zf-C3HC4 PF00097.20 EMG50403.1 - 8.3e-10 38.1 10.2 8.3e-10 38.1 7.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMG50403.1 - 2.2e-09 36.9 9.1 2.2e-09 36.9 6.3 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMG50403.1 - 1.1e-08 34.9 10.6 1.1e-08 34.9 7.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMG50403.1 - 3.1e-07 29.9 7.5 3.1e-07 29.9 5.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMG50403.1 - 5.2e-07 29.4 11.2 5.2e-07 29.4 7.8 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMG50403.1 - 3.4e-06 26.6 4.0 3.4e-06 26.6 2.8 1.9 2 0 0 2 2 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EMG50403.1 - 1e-05 25.5 7.2 1e-05 25.5 5.0 2.6 3 1 0 3 3 3 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EMG50403.1 - 1.3e-05 24.8 9.4 1.3e-05 24.8 6.5 2.4 2 1 0 2 2 2 1 zinc-RING finger domain U-box PF04564.10 EMG50403.1 - 0.0078 16.1 0.0 0.049 13.5 0.0 2.1 2 0 0 2 2 2 1 U-box domain PolC_DP2 PF03833.8 EMG50403.1 - 0.1 10.2 6.0 0.27 8.8 2.0 2.2 2 0 0 2 2 2 0 DNA polymerase II large subunit DP2 Prok-RING_4 PF14447.1 EMG50403.1 - 0.28 10.7 6.0 0.8 9.2 4.2 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 EMG50403.1 - 0.59 10.0 9.5 0.067 13.0 3.0 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EMG50403.1 - 2.3 8.0 13.5 0.13 12.0 4.7 2.4 2 1 1 3 3 3 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EMG50403.1 - 2.8 7.6 15.5 0.054 13.0 5.4 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.2 EMG50403.1 - 3.8 7.3 12.3 19 5.1 0.3 3.0 2 1 0 2 2 2 0 Double zinc ribbon DUF1272 PF06906.6 EMG50403.1 - 4.4 7.2 16.0 1.4 8.8 1.8 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1272) DUF155 PF02582.9 EMG50405.1 - 5.2e-43 146.9 0.3 8.6e-43 146.2 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 SIS PF01380.17 EMG50406.1 - 3.2e-65 217.6 0.1 2.9e-33 114.2 0.1 2.2 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EMG50406.1 - 7.6e-24 84.0 0.0 3.1e-17 62.3 0.0 2.4 2 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EMG50406.1 - 1.3e-18 67.2 0.0 2.6e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EMG50406.1 - 3.2e-11 43.0 0.0 7e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EMG50406.1 - 8.5e-08 31.2 0.1 1.6e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EMG50406.1 - 0.009 15.7 0.0 0.051 13.2 0.0 2.1 2 0 0 2 2 2 1 SIS domain Enkurin PF13864.1 EMG50407.1 - 0.0019 18.3 1.8 0.0019 18.3 1.3 2.4 2 0 0 2 2 2 1 Calmodulin-binding RRM_1 PF00076.17 EMG50407.1 - 0.022 14.3 0.1 0.071 12.7 0.0 2.0 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M18 PF02127.10 EMG50408.1 - 5.6e-137 456.7 0.0 6.6e-137 456.5 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) DS PF01916.12 EMG50409.1 - 1.3e-142 474.2 0.0 1.5e-142 474.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase NDUFA12 PF05071.11 EMG50410.1 - 3.4e-25 88.5 2.3 3.4e-25 88.5 1.6 1.4 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Mak10 PF04112.8 EMG50411.1 - 5.4e-36 123.3 0.1 1.2e-35 122.2 0.1 1.6 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Sec7_N PF12783.2 EMG50411.1 - 0.00088 18.7 1.9 0.0018 17.7 0.3 2.3 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Glyco_hydro_19 PF00182.14 EMG50411.1 - 0.055 13.1 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 Chitinase class I RAMPs PF03787.10 EMG50411.1 - 0.086 12.6 0.0 0.35 10.6 0.0 2.1 2 1 0 2 2 2 0 RAMP superfamily G-alpha PF00503.15 EMG50412.1 - 8.3e-114 380.2 23.5 7.7e-113 377.0 16.3 1.9 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EMG50412.1 - 3e-15 55.9 0.1 3.9e-10 39.2 0.0 2.8 2 0 0 2 2 2 2 ADP-ribosylation factor family Tbf5 PF06331.7 EMG50412.1 - 0.016 14.9 0.1 0.1 12.4 0.0 2.3 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 AAA_29 PF13555.1 EMG50412.1 - 0.03 13.8 0.1 0.071 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EMG50412.1 - 0.035 13.5 0.2 0.088 12.2 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Miro PF08477.8 EMG50412.1 - 0.15 12.5 5.6 0.81 10.1 0.2 3.4 3 1 0 3 3 3 0 Miro-like protein Macoilin PF09726.4 EMG50412.1 - 0.18 10.0 11.0 0.22 9.7 7.6 1.2 1 0 0 1 1 1 0 Transmembrane protein Gtr1_RagA PF04670.7 EMG50412.1 - 0.59 9.2 9.6 0.96 8.5 0.0 2.9 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region FAM60A PF15396.1 EMG50412.1 - 4.8 6.8 11.8 11 5.7 8.2 1.5 1 0 0 1 1 1 0 Protein Family FAM60A Pkinase PF00069.20 EMG50413.1 - 1.8e-73 246.8 0.0 2.6e-73 246.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50413.1 - 5.5e-35 120.6 0.0 8e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG50413.1 - 6.1e-06 25.4 0.0 8e-05 21.7 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EMG50413.1 - 0.065 12.0 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EMG50413.1 - 0.094 12.4 1.2 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Nop25 PF09805.4 EMG50413.1 - 1.1 9.2 12.9 2 8.4 9.0 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) RA PF00788.18 EMG50414.1 - 9.4e-13 48.4 0.0 7.1e-12 45.6 0.0 2.4 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.12 EMG50414.1 - 6.8e-06 25.8 0.0 3.9e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMG50414.1 - 2.7e-05 24.2 0.3 0.0015 18.7 0.0 2.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PAT1 PF09770.4 EMG50414.1 - 0.063 11.5 36.2 0.09 11.0 25.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_L11_N PF03946.9 EMG50415.1 - 9e-18 63.4 0.3 3.1e-17 61.7 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EMG50415.1 - 1.5e-11 44.2 0.6 2.8e-11 43.3 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain ACBP PF00887.14 EMG50416.1 - 1.2e-26 92.1 0.0 2.9e-26 90.9 0.0 1.7 1 0 0 1 1 1 1 Acyl CoA binding protein Med15 PF09606.5 EMG50416.1 - 0.00045 18.5 9.9 0.00051 18.3 6.9 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Mem_trans PF03547.13 EMG50416.1 - 0.72 8.0 6.0 0.19 9.9 0.1 2.0 2 0 0 2 2 2 0 Membrane transport protein ABC2_membrane_3 PF12698.2 EMG50416.1 - 0.86 8.5 4.2 0.36 9.7 0.7 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein Activator_LAG-3 PF11498.3 EMG50416.1 - 1.3 7.7 21.1 1.9 7.1 14.6 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 bZIP_C PF12498.3 EMG50416.1 - 3.2 9.0 11.8 6.2 8.0 8.1 1.4 1 0 0 1 1 1 0 Basic leucine-zipper C terminal WD40 PF00400.27 EMG50417.1 - 4.2e-13 48.6 20.4 0.042 13.7 0.1 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat PQQ_2 PF13360.1 EMG50417.1 - 0.00012 21.6 0.1 1.6 8.1 0.0 4.4 1 1 1 5 5 5 2 PQQ-like domain PQQ_3 PF13570.1 EMG50417.1 - 0.0061 16.8 0.1 1.7 9.0 0.0 3.9 4 0 0 4 4 4 1 PQQ-like domain Nucleoporin_N PF08801.6 EMG50417.1 - 0.027 13.2 1.6 0.071 11.8 0.1 2.2 1 1 1 2 2 2 0 Nup133 N terminal like Hira PF07569.6 EMG50417.1 - 0.045 12.9 0.0 0.24 10.6 0.0 2.2 1 1 1 2 2 2 0 TUP1-like enhancer of split Glyco_hydro_76 PF03663.9 EMG50418.1 - 4.3e-49 167.8 5.1 5.6e-49 167.4 3.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF1680 PF07944.7 EMG50418.1 - 1.9e-05 23.1 0.1 0.028 12.6 0.0 2.3 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) GlcNAc_2-epim PF07221.6 EMG50418.1 - 9.2e-05 21.6 0.1 0.0033 16.5 0.0 2.6 1 1 2 3 3 3 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_88 PF07470.8 EMG50418.1 - 0.00026 20.1 5.9 0.25 10.3 0.6 3.1 1 1 2 3 3 3 3 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.8 EMG50418.1 - 0.0031 16.8 1.0 0.0054 16.0 0.0 1.9 3 0 0 3 3 3 1 D-glucuronyl C5-epimerase C-terminus Sterol_MT_C PF08498.5 EMG50419.1 - 7.4e-31 105.9 0.4 1.1e-30 105.3 0.3 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EMG50419.1 - 3.5e-18 65.8 0.0 6.5e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMG50419.1 - 9.5e-18 64.2 0.0 1.6e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMG50419.1 - 3.5e-13 49.5 0.0 5.8e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMG50419.1 - 4.5e-12 45.6 1.2 6.5e-12 45.0 0.9 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EMG50419.1 - 4.8e-12 46.1 0.0 1.1e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMG50419.1 - 3.5e-11 43.4 0.0 7.2e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMG50419.1 - 4.2e-11 43.4 0.0 9.9e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMG50419.1 - 1.5e-08 34.7 0.0 3.6e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMG50419.1 - 2.9e-07 29.8 0.0 5.2e-07 29.0 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.5 EMG50419.1 - 4.5e-06 26.3 0.1 7.2e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EMG50419.1 - 7.4e-05 22.1 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EMG50419.1 - 0.00027 20.1 0.0 0.00049 19.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 EMG50419.1 - 0.0016 17.5 0.0 0.0028 16.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 EMG50419.1 - 0.0029 17.3 0.3 0.0064 16.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EMG50419.1 - 0.0063 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 EMG50419.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Cnd3 PF12719.2 EMG50420.1 - 1.4e-88 296.7 8.0 1.4e-88 296.7 5.6 3.2 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EMG50420.1 - 5.3e-14 52.2 0.6 2.5e-07 30.8 0.0 5.1 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 EMG50420.1 - 1e-08 34.5 0.3 0.02 14.9 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EMG50420.1 - 0.002 18.5 0.1 5 7.7 0.0 4.2 3 1 1 4 4 4 1 HEAT-like repeat bZIP_1 PF00170.16 EMG50421.1 - 6.8e-10 38.7 7.2 1.7e-09 37.5 5.0 1.6 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.5 EMG50421.1 - 2e-09 37.6 5.3 2e-09 37.6 3.7 3.7 1 1 1 3 3 3 1 Transcription factor PAP1 bZIP_2 PF07716.10 EMG50421.1 - 0.0003 20.5 10.8 0.0003 20.5 7.5 2.0 2 1 0 2 2 2 1 Basic region leucine zipper dsrm PF00035.20 EMG50421.1 - 0.091 13.3 0.8 0.22 12.1 0.1 1.9 2 0 0 2 2 2 0 Double-stranded RNA binding motif NPV_P10 PF05531.7 EMG50421.1 - 0.41 10.9 3.5 1.9 8.7 0.3 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein bZIP_Maf PF03131.12 EMG50421.1 - 0.88 9.9 11.5 0.18 12.1 4.9 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor DivIC PF04977.10 EMG50421.1 - 1.8 8.0 5.1 3 7.3 1.5 2.2 2 0 0 2 2 2 0 Septum formation initiator FmdA_AmdA PF03069.10 EMG50422.1 - 1.9e-147 490.7 0.0 2.2e-147 490.5 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family TauD PF02668.11 EMG50423.1 - 3.7e-44 151.3 0.0 4.7e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sec23_trunk PF04811.10 EMG50424.1 - 3.7e-18 65.7 0.2 1.6e-13 50.6 0.0 2.3 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EMG50424.1 - 1.9e-15 56.1 0.0 6.1e-15 54.5 0.0 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EMG50424.1 - 6.5e-09 36.1 0.0 1.8e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EMG50424.1 - 8e-05 22.1 0.6 0.00027 20.4 0.4 1.9 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger DUF1749 PF08538.5 EMG50425.1 - 6.5e-116 386.4 0.0 7.3e-116 386.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EMG50425.1 - 1e-07 32.0 0.0 1.5e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMG50425.1 - 1.4e-07 31.4 0.0 1e-06 28.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 EMG50425.1 - 0.00083 18.8 0.0 0.0081 15.6 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_1 PF00561.15 EMG50425.1 - 0.0018 17.8 0.0 0.035 13.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EMG50425.1 - 0.002 17.7 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase LCAT PF02450.10 EMG50425.1 - 0.0061 15.5 0.0 0.0097 14.9 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 EMG50425.1 - 0.0093 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Peptidase_S9 PF00326.16 EMG50425.1 - 0.036 13.2 0.0 0.31 10.2 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF915 PF06028.6 EMG50425.1 - 0.039 13.0 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DLH PF01738.13 EMG50425.1 - 0.081 12.1 0.0 9.8 5.3 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family ACOX PF01756.14 EMG50426.1 - 3.8e-57 192.6 0.0 6.6e-57 191.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 EMG50426.1 - 4.9e-17 61.1 0.9 1.1e-16 60.0 0.6 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 EMG50426.1 - 1.5e-13 51.1 0.0 2.7e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 EMG50426.1 - 2e-06 28.0 0.1 5.8e-05 23.2 0.1 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 EMG50426.1 - 0.035 14.3 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain LRR_4 PF12799.2 EMG50428.1 - 4.1e-13 48.6 21.8 0.0016 18.0 0.6 6.8 3 1 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EMG50428.1 - 3.4e-12 45.0 13.7 0.071 13.2 0.0 8.8 9 0 0 9 9 9 4 Leucine Rich repeat LRR_8 PF13855.1 EMG50428.1 - 3.4e-08 33.1 16.3 0.0098 15.6 0.4 5.4 4 1 0 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 EMG50428.1 - 5.4e-06 25.7 10.3 11 6.4 0.0 7.9 9 1 0 9 9 9 2 Leucine Rich Repeat LRR_7 PF13504.1 EMG50428.1 - 0.004 17.1 8.3 1.4 9.4 0.0 6.6 8 0 0 8 8 8 1 Leucine rich repeat AAA PF00004.24 EMG50428.1 - 0.14 12.4 1.3 0.33 11.1 0.9 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) LRR_3 PF07725.7 EMG50428.1 - 0.68 9.8 3.8 12 5.9 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich Repeat AAA_23 PF13476.1 EMG50429.1 - 8.1e-18 65.4 29.4 8.1e-18 65.4 20.4 8.5 1 1 2 3 3 3 1 AAA domain SbcCD_C PF13558.1 EMG50429.1 - 1.5e-10 40.8 0.0 5.4e-10 39.0 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 EMG50429.1 - 1.6e-06 27.5 0.1 1.6e-06 27.5 0.1 4.5 3 2 1 4 4 4 1 RecF/RecN/SMC N terminal domain Rad50_zn_hook PF04423.9 EMG50429.1 - 0.0034 16.8 2.0 0.0034 16.8 1.4 6.7 5 0 0 5 5 5 1 Rad50 zinc hook motif AAA_13 PF13166.1 EMG50429.1 - 0.0057 15.1 0.0 0.0057 15.1 0.0 7.9 1 1 5 7 7 7 3 AAA domain AAA_29 PF13555.1 EMG50429.1 - 0.034 13.6 0.0 0.081 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EMG50429.1 - 0.29 11.2 7.5 0.2 11.8 0.1 3.9 4 0 0 4 4 4 0 AAA domain RRM_1 PF00076.17 EMG50430.1 - 3.5e-78 257.2 10.2 5.8e-18 64.3 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG50430.1 - 4.9e-67 221.8 2.8 1.2e-14 54.0 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG50430.1 - 4.9e-42 141.5 0.4 2.9e-09 36.6 0.1 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMG50430.1 - 2.6e-05 23.9 0.3 0.81 9.5 0.0 4.9 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EMG50430.1 - 0.0016 18.1 0.3 5 6.9 0.0 4.3 3 1 1 4 4 4 1 Limkain b1 Rhomboid PF01694.17 EMG50431.1 - 2.2e-22 79.6 20.7 2.8e-22 79.3 11.9 2.1 2 0 0 2 2 2 1 Rhomboid family ACOX PF01756.14 EMG50433.1 - 1e-48 165.1 0.0 1.8e-48 164.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 EMG50433.1 - 1.4e-14 53.2 0.5 2.7e-14 52.3 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 EMG50433.1 - 2.2e-10 40.8 0.3 4.5e-10 39.8 0.2 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 EMG50433.1 - 0.0058 16.7 0.3 0.11 12.5 0.2 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Far-17a_AIG1 PF04750.9 EMG50434.1 - 5.2e-13 48.6 11.3 3e-12 46.1 7.8 1.8 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein FYVE PF01363.16 EMG50435.1 - 1.3e-12 47.4 6.3 3.1e-12 46.2 4.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger zf-C2H2_3 PF13878.1 EMG50435.1 - 0.66 9.5 3.8 15 5.2 1.3 2.6 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO DEAD PF00270.24 EMG50438.1 - 1.3e-35 122.4 0.7 3.2e-35 121.1 0.2 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG50438.1 - 2.6e-25 88.0 0.0 5e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.1 EMG50438.1 - 0.039 13.5 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Helicase_C_2 PF13307.1 EMG50438.1 - 0.052 13.5 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain Pal1 PF08316.6 EMG50439.1 - 1.4e-41 142.2 2.3 1.4e-41 142.2 1.6 2.5 2 0 0 2 2 2 1 Pal1 cell morphology protein Sod_Fe_C PF02777.13 EMG50439.1 - 1.1e-11 44.5 0.1 0.00017 21.4 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Alg6_Alg8 PF03155.10 EMG50440.1 - 1.2e-137 459.6 44.5 1.4e-137 459.3 30.8 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family TPP_enzyme_N PF02776.13 EMG50441.1 - 4.5e-31 107.6 0.0 6.8e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMG50441.1 - 2.6e-26 92.0 0.0 1.2e-25 89.8 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EMG50441.1 - 1.2e-16 60.6 0.0 2.9e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF3920 PF13058.1 EMG50441.1 - 0.09 12.5 0.0 0.29 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3920) DXP_synthase_N PF13292.1 EMG50441.1 - 0.096 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Fungal_trans PF04082.13 EMG50442.1 - 4.8e-31 107.5 5.5 8.3e-31 106.8 3.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG50442.1 - 8.8e-09 35.1 9.9 1.8e-08 34.1 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.4 EMG50442.1 - 0.15 12.0 8.1 0.13 12.3 3.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Aa_trans PF01490.13 EMG50443.1 - 5.6e-76 255.6 36.5 7.3e-76 255.2 25.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EMG50443.1 - 0.023 13.2 40.6 0.05 12.1 28.1 1.6 1 1 0 1 1 1 0 Amino acid permease DUF21 PF01595.15 EMG50445.1 - 7.6e-32 110.0 0.0 1.2e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EMG50445.1 - 9.6e-06 25.2 0.0 0.1 12.3 0.0 2.5 2 0 0 2 2 2 2 CBS domain Pkinase PF00069.20 EMG50446.1 - 5.5e-50 169.9 0.0 9.4e-50 169.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50446.1 - 3.8e-19 68.7 0.1 8e-19 67.7 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG50446.1 - 0.0079 15.1 0.0 0.035 13.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMG50446.1 - 0.16 11.7 0.1 0.56 9.8 0.2 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ndc1_Nup PF09531.5 EMG50446.1 - 2.1 6.6 13.9 2.7 6.2 9.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF605 PF04652.11 EMG50446.1 - 4.9 6.4 22.0 7.3 5.8 15.3 1.2 1 0 0 1 1 1 0 Vta1 like Solute_trans_a PF03619.11 EMG50447.1 - 8.3e-74 248.3 4.2 1.2e-73 247.8 2.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha mIF3 PF14877.1 EMG50448.1 - 3.4e-32 111.2 9.2 5.4e-32 110.6 6.3 1.3 1 0 0 1 1 1 1 Mitochondrial translation initiation factor Ndc1_Nup PF09531.5 EMG50448.1 - 3 6.1 8.7 2.2 6.6 4.9 1.4 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ribosomal_S2 PF00318.15 EMG50450.1 - 2.6e-41 141.1 0.1 3.1e-21 75.5 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 MFS_1 PF07690.11 EMG50451.1 - 1.1e-17 63.8 37.4 4.6e-17 61.7 16.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DNA_pol3_delta PF06144.8 EMG50451.1 - 0.039 13.4 1.4 0.12 11.8 0.2 2.0 2 0 0 2 2 2 0 DNA polymerase III, delta subunit SMI1_KNR4 PF09346.5 EMG50452.1 - 1.8e-50 170.3 0.6 1.8e-50 170.3 0.4 2.6 3 1 0 3 3 3 1 SMI1 / KNR4 family (SUKH-1) CBM_20 PF00686.14 EMG50452.1 - 0.0044 16.5 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain Pyr_redox_2 PF07992.9 EMG50453.1 - 1.2e-14 54.6 0.0 3.1e-14 53.3 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMG50453.1 - 1.2e-08 35.2 0.9 8.1e-05 22.7 0.1 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMG50453.1 - 2e-06 28.1 0.0 6.7e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMG50453.1 - 7.1e-05 21.8 0.4 0.0051 15.7 0.1 2.3 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EMG50453.1 - 0.0034 17.1 0.6 2.3 7.9 0.0 3.8 4 0 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.19 EMG50453.1 - 0.045 12.6 1.5 1.8 7.3 0.2 3.2 3 1 1 4 4 4 0 FAD dependent oxidoreductase CheB_methylest PF01339.12 EMG50453.1 - 0.066 12.6 0.2 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 CheB methylesterase Abhydrolase_6 PF12697.2 EMG50453.1 - 0.068 13.0 0.0 0.15 11.9 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family GIDA PF01134.17 EMG50453.1 - 2.4 6.9 7.0 0.75 8.5 0.8 2.8 3 1 1 4 4 4 0 Glucose inhibited division protein A Cyclin_N PF00134.18 EMG50454.1 - 4.1e-14 52.2 1.1 8.4e-14 51.2 0.4 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain VAD1-2 PF15310.1 EMG50454.1 - 0.059 13.0 7.9 0.084 12.5 5.5 1.1 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling DFP PF04127.10 EMG50455.1 - 2.6e-18 66.3 0.0 6.8e-11 42.1 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Phage_sheath_1 PF04984.9 EMG50455.1 - 0.12 10.8 0.0 0.2 10.0 0.0 1.3 1 0 0 1 1 1 0 Phage tail sheath protein Bac_surface_Ag PF01103.18 EMG50456.1 - 4.1e-34 118.4 10.5 6.7e-34 117.8 7.3 1.3 1 0 0 1 1 1 1 Surface antigen RNase_Zc3h12a PF11977.3 EMG50456.1 - 0.072 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain WD40 PF00400.27 EMG50457.1 - 2e-08 33.7 9.8 0.18 11.7 0.0 6.2 6 1 1 7 7 7 3 WD domain, G-beta repeat CPSF_A PF03178.10 EMG50457.1 - 0.0011 18.1 0.3 0.0041 16.2 0.1 2.0 2 1 1 3 3 3 1 CPSF A subunit region DIE2_ALG10 PF04922.7 EMG50458.1 - 6.2e-83 278.9 23.4 9e-83 278.3 16.2 1.2 1 0 0 1 1 1 1 DIE2/ALG10 family CDC45 PF02724.9 EMG50458.1 - 0.2 9.6 1.4 0.25 9.3 0.3 1.5 2 0 0 2 2 2 0 CDC45-like protein Rick_17kDa_Anti PF05433.10 EMG50459.1 - 6.5e-08 32.1 7.8 6.5e-08 32.1 5.4 2.8 2 1 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 EMG50459.1 - 0.0023 17.6 3.5 0.0023 17.6 2.4 2.2 1 1 1 2 2 2 1 Glycine-zipper containing OmpA-like membrane domain Kinesin PF00225.18 EMG50460.1 - 4.2e-118 393.8 0.3 6.4e-118 393.2 0.2 1.3 1 0 0 1 1 1 1 Kinesin motor domain TRAM_LAG1_CLN8 PF03798.11 EMG50461.1 - 1.4e-32 112.9 18.0 1.7e-32 112.5 12.4 1.0 1 0 0 1 1 1 1 TLC domain DUF1510 PF07423.6 EMG50461.1 - 0.0046 16.3 1.9 0.0066 15.8 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Trypan_PARP PF05887.6 EMG50461.1 - 0.13 12.0 2.9 0.21 11.3 2.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PIG-P PF08510.7 EMG50461.1 - 0.17 11.5 0.0 0.17 11.5 0.0 2.5 2 1 0 2 2 2 0 PIG-P TRAP_alpha PF03896.11 EMG50461.1 - 0.23 10.4 3.6 0.35 9.8 2.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF3488 PF11992.3 EMG50461.1 - 0.27 9.8 1.5 0.33 9.5 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) TLP-20 PF06088.6 EMG50461.1 - 0.48 10.0 5.9 0.71 9.5 4.1 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF2457 PF10446.4 EMG50461.1 - 2.5 6.7 13.3 3.3 6.3 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pkinase PF00069.20 EMG50462.1 - 3e-32 111.7 0.2 1.3e-31 109.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50462.1 - 5.8e-12 45.2 0.0 1.1e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 EMG50462.1 - 0.41 9.9 0.0 0.41 9.9 0.0 2.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL 2OG-Fe_Oxy_2 PF10014.4 EMG50463.1 - 0.02 14.2 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe dioxygenase Methyltransf_23 PF13489.1 EMG50464.1 - 9.7e-15 54.6 0.0 1.4e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMG50464.1 - 1.3e-14 54.0 0.1 2e-14 53.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMG50464.1 - 2e-14 53.8 0.0 3.6e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMG50464.1 - 1.4e-13 51.1 0.0 2.4e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMG50464.1 - 2.4e-10 40.9 0.0 4e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMG50464.1 - 1.3e-09 38.3 0.0 3.3e-09 37.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMG50464.1 - 1.3e-06 27.7 0.0 2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EMG50464.1 - 7.5e-06 25.2 0.0 1.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EMG50464.1 - 1.5e-05 25.0 0.0 2.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMG50464.1 - 0.00027 20.3 0.0 0.00048 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EMG50464.1 - 0.0061 15.7 0.0 0.0089 15.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Pox_MCEL PF03291.11 EMG50464.1 - 0.0089 14.9 0.1 0.013 14.3 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme NNMT_PNMT_TEMT PF01234.12 EMG50464.1 - 0.027 13.4 0.0 0.055 12.4 0.0 1.5 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family PCMT PF01135.14 EMG50464.1 - 0.052 13.0 0.0 0.1 12.0 0.0 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CmcI PF04989.7 EMG50464.1 - 0.055 12.7 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase CheR PF01739.13 EMG50464.1 - 0.066 12.4 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain DUF4385 PF14328.1 EMG50464.1 - 0.08 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4385) UQ_con PF00179.21 EMG50465.1 - 4.6e-29 100.6 0.2 7.8e-29 99.8 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EMG50465.1 - 0.0042 16.9 1.3 0.0053 16.6 0.1 1.9 2 0 0 2 2 2 1 RWD domain Sel1 PF08238.7 EMG50466.1 - 5.9e-42 141.1 27.3 1.2e-08 35.3 0.2 8.3 7 1 1 8 8 8 7 Sel1 repeat Fox-1_C PF12414.3 EMG50466.1 - 0.049 14.0 0.1 0.16 12.4 0.0 1.9 1 0 0 1 1 1 0 Calcitonin gene-related peptide regulator C terminal TauD PF02668.11 EMG50467.1 - 1.1e-23 84.1 0.1 5.7e-23 81.9 0.0 1.8 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family EF-hand_4 PF12763.2 EMG50468.1 - 2.2e-07 30.5 0.2 2.2e-07 30.5 0.2 2.7 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.1 EMG50468.1 - 0.0037 16.8 0.0 0.014 15.0 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair NOB1_Zn_bind PF08772.6 EMG50469.1 - 4.5e-28 96.8 1.0 9.2e-28 95.8 0.7 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like eIF-3c_N PF05470.7 EMG50469.1 - 0.03 12.4 4.7 0.045 11.8 3.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Zn-ribbon_8 PF09723.5 EMG50469.1 - 0.048 13.6 1.4 0.11 12.4 1.0 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Herpes_LMP2 PF07415.6 EMG50469.1 - 0.42 9.1 1.8 0.62 8.5 1.3 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Trypan_PARP PF05887.6 EMG50469.1 - 5.1 6.9 26.6 8.7 6.1 18.5 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GST_N_3 PF13417.1 EMG50470.1 - 4.3e-08 33.2 0.0 1.4e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMG50470.1 - 5.1e-08 32.8 0.0 1.3e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMG50470.1 - 4.7e-07 29.7 0.0 1.1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMG50470.1 - 4.8e-07 29.8 0.0 8.6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMG50470.1 - 1.9e-06 27.6 0.0 2.6e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMG50470.1 - 2.3e-06 28.0 0.0 4.4e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HDA2-3 PF11496.3 EMG50471.1 - 5.5e-69 232.2 9.3 5.5e-69 232.2 6.4 2.5 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_13 PF13166.1 EMG50471.1 - 3.2e-06 25.9 17.1 3.2e-06 25.9 11.8 2.2 2 0 0 2 2 2 2 AAA domain Reo_sigmaC PF04582.7 EMG50471.1 - 0.15 11.2 4.5 0.044 12.9 0.8 1.8 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Pyridoxal_deC PF00282.14 EMG50472.1 - 1.6e-19 69.6 0.0 2.3e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.12 EMG50472.1 - 4.3e-08 32.5 0.0 6.6e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EMG50472.1 - 1.1e-05 24.3 0.0 2.8e-05 23.0 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EMG50472.1 - 0.046 11.9 0.0 0.074 11.3 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme VIT1 PF01988.14 EMG50473.1 - 5.6e-60 202.4 4.1 5.6e-60 202.4 2.8 1.5 2 0 0 2 2 2 1 VIT family PQ-loop PF04193.9 EMG50474.1 - 7.8e-34 115.0 20.7 2.6e-17 62.1 0.9 3.2 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 EMG50474.1 - 0.18 11.6 0.1 0.18 11.6 0.1 2.5 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange TauD PF02668.11 EMG50476.1 - 2.5e-13 50.3 0.3 7.5e-13 48.7 0.1 1.7 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family Proteasome PF00227.21 EMG50477.1 - 4.7e-59 198.8 0.2 5.7e-59 198.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMG50477.1 - 7.9e-14 50.6 1.2 1.2e-13 50.0 0.3 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature GPAT_N PF14829.1 EMG50478.1 - 0.04 13.6 1.2 0.097 12.3 0.1 2.2 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal Peptidase_C48 PF02902.14 EMG50479.1 - 4.5e-09 36.2 4.7 4.5e-09 36.2 3.3 1.9 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_M24 PF00557.19 EMG50480.1 - 5.1e-48 163.4 0.0 6.6e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EMG50480.1 - 5.2e-29 100.3 0.0 8.2e-29 99.6 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_C74 PF12387.3 EMG50480.1 - 0.074 12.2 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Pestivirus NS2 peptidase Cortex-I_coil PF09304.5 EMG50481.1 - 0.043 13.8 0.2 0.047 13.7 0.1 1.1 1 0 0 1 1 1 0 Cortexillin I, coiled coil SCF PF02404.10 EMG50481.1 - 0.053 12.7 0.0 0.058 12.5 0.0 1.1 1 0 0 1 1 1 0 Stem cell factor DUF4163 PF13739.1 EMG50481.1 - 0.1 13.4 0.8 0.14 12.9 0.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4163) HCNGP PF07818.8 EMG50481.1 - 0.11 12.5 0.2 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 HCNGP-like protein GLTP PF08718.6 EMG50481.1 - 0.13 12.2 0.2 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) Podoplanin PF05808.6 EMG50482.1 - 0.3 10.6 8.1 0.32 10.5 5.6 1.0 1 0 0 1 1 1 0 Podoplanin Phage_sheath_1 PF04984.9 EMG50482.1 - 2.7 6.3 9.2 3.7 5.8 6.4 1.2 1 0 0 1 1 1 0 Phage tail sheath protein Herpes_BLLF1 PF05109.8 EMG50482.1 - 2.9 5.7 16.0 3 5.6 11.1 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Mitofilin PF09731.4 EMG50483.1 - 0.23 10.0 12.5 0.24 10.0 8.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein AvrE PF11725.3 EMG50483.1 - 0.69 6.8 9.0 0.77 6.7 6.3 1.0 1 0 0 1 1 1 0 Pathogenicity factor GEMIN8 PF15348.1 EMG50483.1 - 0.78 9.7 9.1 1 9.3 6.3 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DUF1510 PF07423.6 EMG50483.1 - 1.1 8.6 15.7 1.3 8.3 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF605 PF04652.11 EMG50483.1 - 2.9 7.2 21.3 3.1 7.1 14.7 1.1 1 0 0 1 1 1 0 Vta1 like DUF2052 PF09747.4 EMG50483.1 - 3.9 7.3 9.8 5.3 6.9 6.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Hid1 PF12722.2 EMG50483.1 - 4.3 4.8 14.2 4.6 4.7 9.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDHD PF02862.12 EMG50483.1 - 5.4 6.7 12.5 8.3 6.1 8.7 1.4 1 0 0 1 1 1 0 DDHD domain NPR3 PF03666.8 EMG50483.1 - 7.9 4.8 11.5 9.3 4.6 8.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SDA1 PF05285.7 EMG50483.1 - 8.7 5.5 12.7 9.6 5.3 8.8 1.1 1 0 0 1 1 1 0 SDA1 RR_TM4-6 PF06459.7 EMG50483.1 - 8.7 6.1 12.5 10 5.8 8.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Herpes_LMP2 PF07415.6 EMG50483.1 - 9.1 4.7 12.0 11 4.5 8.3 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Arginase PF00491.16 EMG50484.1 - 2.2e-72 243.6 0.2 2.8e-72 243.3 0.1 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EMG50484.1 - 0.023 14.8 0.4 0.051 13.7 0.2 1.7 1 1 0 1 1 1 0 UPF0489 domain KRE9 PF05390.6 EMG50485.1 - 6.8e-44 148.6 16.1 6.8e-44 148.6 11.1 1.7 2 0 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 EMG50485.1 - 6.6e-15 55.3 6.4 7.7e-15 55.1 1.4 2.3 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF912 PF06024.7 EMG50486.1 - 0.0057 16.6 0.0 0.0072 16.3 0.0 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) SKN1 PF03935.10 EMG50487.1 - 1.1e-250 832.0 5.0 1.4e-250 831.7 3.4 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Aminotran_1_2 PF00155.16 EMG50489.1 - 7.3e-39 133.7 0.0 9.7e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EMG50489.1 - 0.016 14.3 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Aldedh PF00171.17 EMG50490.1 - 1.3e-151 505.0 0.0 1.5e-151 504.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Arginase PF00491.16 EMG50493.1 - 8.9e-81 271.2 0.1 1.1e-80 270.9 0.1 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EMG50493.1 - 0.029 14.5 0.4 0.076 13.2 0.3 1.7 1 1 0 1 1 1 0 UPF0489 domain DUF963 PF06131.6 EMG50494.1 - 0.13 11.5 1.8 1.4 8.2 0.2 2.5 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) FAM47 PF14642.1 EMG50495.1 - 3.8 6.7 5.1 12 5.0 1.8 1.9 1 1 2 3 3 3 0 FAM47 family HA2 PF04408.18 EMG50496.1 - 3.6e-22 78.2 0.1 1e-21 76.8 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EMG50496.1 - 9.4e-16 57.6 0.0 2.9e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EMG50496.1 - 1.9e-13 50.0 0.0 4.5e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EMG50496.1 - 8.3e-09 35.6 0.1 8.7e-08 32.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 EMG50496.1 - 3e-08 33.3 0.1 6.3e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EMG50496.1 - 0.00084 18.3 0.0 0.0016 17.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 EMG50496.1 - 0.001 18.5 0.3 0.0038 16.6 0.2 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 EMG50496.1 - 0.0083 16.1 1.1 0.061 13.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EMG50496.1 - 0.013 15.3 4.6 0.36 10.7 0.1 3.8 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EMG50496.1 - 0.023 14.1 0.1 4.4 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_30 PF13604.1 EMG50496.1 - 0.047 13.2 0.2 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EMG50496.1 - 0.076 12.4 0.0 0.2 11.0 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Flavi_DEAD PF07652.9 EMG50496.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_19 PF13245.1 EMG50496.1 - 0.17 11.6 0.1 0.79 9.5 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain DUF4407 PF14362.1 EMG50496.1 - 8.8 5.1 6.8 17 4.2 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) WSC PF01822.14 EMG50497.1 - 5.6e-11 42.2 12.8 5.6e-11 42.2 8.9 2.8 2 1 0 2 2 2 1 WSC domain SKG6 PF08693.5 EMG50497.1 - 0.031 13.5 0.0 0.13 11.6 0.0 2.2 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.1 EMG50497.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Yip1 PF04893.12 EMG50497.1 - 0.16 11.4 0.8 0.23 10.9 0.1 1.5 2 0 0 2 2 2 0 Yip1 domain DUF605 PF04652.11 EMG50497.1 - 0.18 11.2 12.4 0.22 10.8 8.6 1.3 1 0 0 1 1 1 0 Vta1 like Rick_17kDa_Anti PF05433.10 EMG50497.1 - 9.4 5.9 11.6 25 4.6 8.1 1.7 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF2370 PF10176.4 EMG50498.1 - 6.7e-84 280.8 0.0 6.7e-84 280.8 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) Mito_carr PF00153.22 EMG50499.1 - 2.8e-63 209.6 7.2 1.2e-22 79.3 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 EMG50499.1 - 0.19 11.7 2.8 10 6.1 0.0 3.1 2 1 2 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family adh_short PF00106.20 EMG50500.1 - 6.2e-27 94.5 0.0 1.5e-26 93.3 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMG50500.1 - 2e-20 73.6 0.1 4.3e-20 72.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMG50500.1 - 3.6e-09 36.5 0.0 2.7e-08 33.6 0.0 2.3 1 1 1 2 2 2 1 KR domain DUF1776 PF08643.5 EMG50500.1 - 1.2e-05 24.5 0.0 0.00069 18.8 0.0 2.2 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EMG50500.1 - 2.7e-05 23.7 0.0 5.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMG50500.1 - 0.087 12.8 0.0 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EMG50500.1 - 0.11 12.2 0.1 0.38 10.5 0.1 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PRK PF00485.13 EMG50501.1 - 5.2e-58 195.8 0.1 1.7e-57 194.0 0.0 1.8 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 EMG50501.1 - 5.3e-34 117.2 0.0 8.4e-34 116.5 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 EMG50501.1 - 4.7e-06 27.4 0.0 1.3e-05 25.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMG50501.1 - 5.8e-06 26.6 0.0 1.6e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 EMG50501.1 - 0.00063 19.4 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.7 EMG50501.1 - 0.0011 18.1 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin KAP_NTPase PF07693.9 EMG50501.1 - 0.0017 17.3 0.0 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain Miro PF08477.8 EMG50501.1 - 0.0031 17.9 0.1 0.65 10.5 0.1 3.1 2 1 0 3 3 3 1 Miro-like protein AAA_16 PF13191.1 EMG50501.1 - 0.011 15.6 0.0 0.044 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 EMG50501.1 - 0.014 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EMG50501.1 - 0.065 12.7 0.0 0.098 12.1 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.17 EMG50501.1 - 0.089 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Asp-B-Hydro_N PF05279.6 EMG50503.1 - 5.6 6.7 32.9 9.1 6.0 22.8 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SNF5 PF04855.7 EMG50504.1 - 2.8e-60 203.8 1.0 2.8e-60 203.8 0.7 3.8 3 2 0 3 3 3 1 SNF5 / SMARCB1 / INI1 DNA_pol_B PF00136.16 EMG50506.1 - 1.6e-116 389.9 10.3 2.4e-116 389.2 7.2 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EMG50506.1 - 7e-68 227.6 0.9 1.8e-67 226.3 0.6 1.8 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EMG50506.1 - 1e-35 123.1 0.0 2.6e-35 121.8 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EMG50506.1 - 4.7e-23 80.7 12.8 1.4e-22 79.2 8.9 1.9 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal Pup PF05639.6 EMG50506.1 - 0.31 11.5 0.1 0.31 11.5 0.0 4.0 4 0 0 4 4 4 0 Pup-like protein Voltage_CLC PF00654.15 EMG50507.1 - 6.5e-14 51.7 1.0 6.5e-14 51.7 0.7 2.3 1 1 2 3 3 3 1 Voltage gated chloride channel DUF2963 PF11178.3 EMG50507.1 - 0.084 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2963) AATase PF07247.7 EMG50508.1 - 3.7e-113 378.6 3.5 4.4e-113 378.3 2.4 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase DUF3186 PF11382.3 EMG50509.1 - 0.033 13.3 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) Cwf_Cwc_15 PF04889.7 EMG50509.1 - 0.34 10.6 8.7 0.39 10.3 6.0 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.3 EMG50509.1 - 0.37 10.6 13.5 0.48 10.3 9.4 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2076 PF09849.4 EMG50509.1 - 7.7 6.4 9.2 9.3 6.2 6.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Syntaxin_2 PF14523.1 EMG50510.1 - 2e-20 72.6 7.2 2e-20 72.6 5.0 2.8 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EMG50510.1 - 9.4e-18 63.6 13.1 3.5e-17 61.8 4.6 3.0 3 0 0 3 3 3 1 SNARE domain Synaptobrevin PF00957.16 EMG50510.1 - 0.00039 19.9 1.4 0.00039 19.9 1.0 2.6 3 0 0 3 3 3 1 Synaptobrevin TBPIP PF07106.8 EMG50510.1 - 0.0062 16.1 4.3 0.0062 16.1 3.0 2.4 1 1 0 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) MT PF12777.2 EMG50510.1 - 0.0069 15.1 0.2 0.0069 15.1 0.2 1.5 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor MCPsignal PF00015.16 EMG50510.1 - 0.012 15.1 13.3 0.025 14.1 3.0 2.5 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF912 PF06024.7 EMG50510.1 - 0.073 13.1 0.3 0.073 13.1 0.2 3.2 2 1 2 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) COG2 PF06148.6 EMG50510.1 - 0.097 12.5 4.0 1.1 9.1 0.2 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.7 EMG50510.1 - 0.91 9.3 8.9 3.8 7.3 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TrbI PF03743.9 EMG50510.1 - 1.1 8.7 3.9 1.4 8.3 0.1 2.5 2 1 1 3 3 3 0 Bacterial conjugation TrbI-like protein Laminin_II PF06009.7 EMG50510.1 - 5.5 6.7 13.7 0.96 9.1 0.7 2.6 1 1 0 2 2 2 0 Laminin Domain II Voltage_CLC PF00654.15 EMG50511.1 - 2.3e-53 181.4 11.9 2.8e-53 181.1 8.2 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 EMG50511.1 - 1.5e-15 56.6 0.2 4.6e-10 39.1 0.1 2.6 2 0 0 2 2 2 2 CBS domain CBF PF03914.12 EMG50512.1 - 9.8e-44 148.6 0.1 9.8e-44 148.6 0.1 3.9 5 1 0 5 5 5 1 CBF/Mak21 family ATP-synt_C PF00137.16 EMG50513.1 - 2.1e-31 107.6 19.0 6.4e-19 67.6 7.6 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 EMG50513.1 - 0.13 11.8 1.9 0.12 11.9 0.2 1.6 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A DUF2970 PF11174.3 EMG50513.1 - 4.7 6.8 8.5 0.85 9.2 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Ras PF00071.17 EMG50514.1 - 2.1e-19 69.4 0.1 5.2e-19 68.2 0.1 1.6 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EMG50514.1 - 3.5e-14 53.3 0.2 1e-13 51.8 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Pkinase PF00069.20 EMG50515.1 - 6.4e-65 218.8 0.0 1.8e-64 217.4 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50515.1 - 2.8e-36 124.9 0.0 7.9e-36 123.4 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EMG50515.1 - 8.2e-29 99.1 12.5 6.1e-15 54.7 0.9 2.7 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 EMG50515.1 - 3.6e-20 71.4 33.6 1.3e-11 44.0 8.4 2.7 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EMG50515.1 - 6.6e-12 45.7 1.5 6.6e-12 45.7 1.0 3.0 3 0 0 3 3 3 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMG50515.1 - 0.0018 17.3 0.0 0.0044 16.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Uds1 PF15456.1 EMG50515.1 - 0.025 14.5 0.1 0.025 14.5 0.1 4.0 4 1 0 4 4 4 0 Up-regulated During Septation Mut7-C PF01927.11 EMG50516.1 - 0.49 10.3 4.6 1 9.2 0.3 2.5 2 0 0 2 2 2 0 Mut7-C RNAse domain SUN PF03856.8 EMG50517.1 - 3.2e-73 246.0 10.5 4e-73 245.7 7.3 1.0 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF2235 PF09994.4 EMG50518.1 - 1.1e-78 264.3 0.0 1.4e-78 264.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Rieske PF00355.21 EMG50519.1 - 7e-19 67.1 0.0 1.1e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 EMG50519.1 - 1.7e-18 66.5 3.0 2.7e-18 65.9 2.1 1.3 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region HECT PF00632.20 EMG50520.1 - 3.4e-87 292.5 0.5 6.5e-87 291.6 0.4 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-LSD1 PF06943.7 EMG50520.1 - 0.0019 17.7 1.6 0.0045 16.5 1.1 1.7 1 0 0 1 1 1 1 LSD1 zinc finger Nucleopor_Nup85 PF07575.8 EMG50521.1 - 1.9e-63 214.5 5.9 3e-63 213.9 4.1 1.3 1 0 0 1 1 1 1 Nup85 Nucleoporin TEA PF01285.13 EMG50522.1 - 3.9e-32 111.9 1.3 3.9e-32 111.9 0.9 3.0 2 1 0 2 2 2 2 TEA/ATTS domain family Pkinase PF00069.20 EMG50523.1 - 3e-57 193.7 0.0 7.3e-57 192.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain zf-HC5HC2H_2 PF13832.1 EMG50523.1 - 6e-31 106.7 7.9 6e-31 106.7 5.5 2.6 2 0 0 2 2 2 1 PHD-zinc-finger like domain Pkinase_Tyr PF07714.12 EMG50523.1 - 7.9e-28 97.2 0.0 1.5e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase zf-HC5HC2H PF13771.1 EMG50523.1 - 1.5e-27 95.5 5.2 1.5e-27 95.5 3.6 3.6 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 EMG50523.1 - 6.5e-14 52.4 5.9 6.5e-14 52.4 4.1 2.2 3 0 0 3 3 3 1 Enhancer of polycomb-like PHD_2 PF13831.1 EMG50523.1 - 1.2e-13 50.0 2.1 1.2e-13 50.0 1.5 2.4 2 0 0 2 2 2 1 PHD-finger Kinase-like PF14531.1 EMG50523.1 - 1.5e-10 40.4 0.0 3.9e-10 39.1 0.0 1.7 1 1 0 1 1 1 1 Kinase-like PHD PF00628.24 EMG50523.1 - 7.3e-08 31.9 9.9 7.3e-08 31.9 6.9 3.2 3 0 0 3 3 3 1 PHD-finger RGS PF00615.14 EMG50524.1 - 1.9e-06 27.9 0.5 0.00013 22.0 0.0 2.7 2 0 0 2 2 2 2 Regulator of G protein signaling domain Ribosomal_L19e PF01280.15 EMG50525.1 - 4.8e-58 195.1 10.4 4.8e-58 195.1 7.2 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e DUF349 PF03993.7 EMG50525.1 - 6 7.0 15.0 31 4.8 0.0 3.0 2 1 1 3 3 3 0 Domain of Unknown Function (DUF349) DUF2423 PF10338.4 EMG50526.1 - 2.9e-19 68.7 7.7 2.9e-19 68.7 5.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Sporozoite_P67 PF05642.6 EMG50526.1 - 4.5 5.0 8.1 4.5 5.0 5.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Uds1 PF15456.1 EMG50526.1 - 7.6 6.5 9.4 9.8 6.1 6.5 1.4 1 0 0 1 1 1 0 Up-regulated During Septation ATP-grasp PF02222.17 EMG50527.1 - 6.2e-65 217.7 0.0 9.1e-65 217.1 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain AIRC PF00731.15 EMG50527.1 - 2.1e-63 212.0 0.9 3.6e-63 211.3 0.6 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp_4 PF13535.1 EMG50527.1 - 7.3e-10 38.8 0.0 1.5e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EMG50527.1 - 2.1e-07 30.4 0.0 4.4e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain 2-Hacid_dh_C PF02826.14 EMG50527.1 - 0.00013 21.1 0.0 0.00028 20.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dala_Dala_lig_C PF07478.8 EMG50527.1 - 0.00017 21.0 0.0 0.0028 17.0 0.0 2.4 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EMG50527.1 - 0.0053 16.6 0.0 0.018 14.9 0.0 2.0 2 1 0 2 2 2 1 ATP-grasp domain CoA_binding_2 PF13380.1 EMG50527.1 - 0.013 15.6 0.1 25 5.0 0.0 3.6 3 1 1 4 4 4 0 CoA binding domain CPSase_L_chain PF00289.17 EMG50527.1 - 0.013 15.5 0.1 0.05 13.7 0.0 2.0 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain XdhC_C PF13478.1 EMG50527.1 - 0.069 13.4 0.0 0.56 10.5 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain ATPgrasp_Ter PF15632.1 EMG50527.1 - 0.07 11.8 0.0 0.33 9.6 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon Colicin_Ia PF11504.3 EMG50527.1 - 0.083 12.7 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 Colicin Ia RRM_1 PF00076.17 EMG50528.1 - 1.1e-12 47.3 0.3 1.1e-12 47.3 0.2 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG50528.1 - 1.1e-10 41.2 0.0 2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EMG50528.1 - 0.00048 20.5 1.3 0.00048 20.5 0.9 3.0 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EMG50528.1 - 0.0041 16.9 0.1 0.0041 16.9 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMG50528.1 - 0.0057 16.4 0.5 0.0057 16.4 0.4 2.5 2 1 1 3 3 3 1 RNA binding motif Na_H_antiport_2 PF13726.1 EMG50528.1 - 0.02 14.8 0.0 0.075 12.9 0.0 1.9 1 1 1 2 2 2 0 Na+-H+ antiporter family K_channel_TID PF07941.6 EMG50528.1 - 5.9 7.2 10.7 3 8.1 2.3 3.0 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain SPA PF08616.5 EMG50529.1 - 2.3e-35 120.6 0.2 7.7e-35 119.0 0.1 2.0 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.7 EMG50529.1 - 8e-33 113.4 0.1 1.9e-32 112.2 0.1 1.7 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.4 EMG50529.1 - 1.8e-16 59.6 0.9 1.2e-11 43.7 0.0 2.6 2 1 0 2 2 2 2 Transport protein Avl9 DUF2347 PF09804.4 EMG50529.1 - 1.6e-05 24.3 1.4 0.0059 15.9 0.4 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) DENN PF02141.16 EMG50529.1 - 0.056 13.1 5.0 3.3 7.3 0.2 3.5 4 0 0 4 4 4 0 DENN (AEX-3) domain zf-C2H2_4 PF13894.1 EMG50531.1 - 0.00017 21.6 10.0 0.018 15.3 0.2 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EMG50531.1 - 0.0047 17.2 0.5 0.0047 17.2 0.3 4.4 4 1 0 4 4 4 2 Zinc finger, C2H2 type Pap_E4 PF02711.9 EMG50531.1 - 8.1 7.3 18.1 4 8.3 9.2 2.5 2 1 0 2 2 2 0 E4 protein Mito_carr PF00153.22 EMG50532.1 - 2.3e-44 148.9 8.2 1.3e-16 60.0 0.2 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein AAA PF00004.24 EMG50533.1 - 1.9e-43 147.8 0.2 1e-42 145.4 0.0 2.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DnaJ PF00226.26 EMG50533.1 - 8.4e-22 76.6 4.2 2.4e-21 75.2 2.9 1.9 1 0 0 1 1 1 1 DnaJ domain AAA_2 PF07724.9 EMG50533.1 - 5e-07 29.7 0.1 2.1e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EMG50533.1 - 6.5e-07 29.1 0.0 2e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMG50533.1 - 1.8e-05 24.8 0.0 7.6e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMG50533.1 - 3.2e-05 24.0 1.5 0.00075 19.6 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMG50533.1 - 0.00043 19.9 0.1 0.00086 19.0 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EMG50533.1 - 0.00051 19.1 0.0 0.001 18.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EMG50533.1 - 0.00055 20.7 3.6 0.0011 19.7 0.0 3.3 4 0 0 4 4 3 1 AAA domain AAA_14 PF13173.1 EMG50533.1 - 0.00078 19.3 0.4 0.0072 16.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EMG50533.1 - 0.0011 18.4 1.7 0.0012 18.2 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.1 EMG50533.1 - 0.0014 18.6 1.1 0.012 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EMG50533.1 - 0.0088 15.9 0.0 0.0088 15.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain PhoH PF02562.11 EMG50533.1 - 0.011 14.9 0.1 0.13 11.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.6 EMG50533.1 - 0.019 14.5 0.0 0.061 12.9 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EMG50533.1 - 0.02 15.0 0.0 0.13 12.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.16 EMG50533.1 - 0.032 13.3 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EMG50533.1 - 0.075 13.3 0.0 0.075 13.3 0.0 3.5 4 0 0 4 4 3 0 AAA domain AAA_25 PF13481.1 EMG50533.1 - 0.089 12.1 1.8 0.36 10.1 0.0 2.7 3 1 1 4 4 4 0 AAA domain TPR_8 PF13181.1 EMG50533.1 - 1.3 8.9 11.0 11 6.1 0.0 5.3 6 0 0 6 6 4 0 Tetratricopeptide repeat Peptidase_M28 PF04389.12 EMG50534.1 - 3e-33 115.0 0.0 5.1e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EMG50534.1 - 3.3e-14 52.4 0.0 7e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M42 PF05343.9 EMG50534.1 - 0.016 14.0 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Pyrophosphatase PF00719.14 EMG50535.1 - 3.3e-52 176.0 0.1 5.9e-52 175.2 0.1 1.4 1 0 0 1 1 1 1 Inorganic pyrophosphatase TP6A_N PF04406.9 EMG50535.1 - 3.3e-06 26.6 0.3 7.4e-06 25.5 0.2 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase RCR PF12273.3 EMG50536.1 - 3.7e-40 137.4 16.0 4.7e-39 133.9 10.5 2.6 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF1443 PF07280.6 EMG50536.1 - 0.14 11.7 0.7 0.21 11.1 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1443) LIM_bind PF01803.11 EMG50537.1 - 8e-52 175.7 0.4 8e-52 175.7 0.3 4.9 5 0 0 5 5 5 1 LIM-domain binding protein PAPA-1 PF04795.7 EMG50537.1 - 1.5e-07 32.0 8.0 1.5e-07 32.0 5.6 3.1 3 0 0 3 3 3 1 PAPA-1-like conserved region Flocculin_t3 PF13928.1 EMG50538.1 - 7.9e-05 22.7 17.4 7.9e-05 22.7 12.1 10.2 3 2 2 5 5 5 1 Flocculin type 3 repeat ProRS-C_1 PF09180.6 EMG50538.1 - 0.024 14.5 5.6 1 9.3 0.2 4.3 3 1 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal Response_reg PF00072.19 EMG50538.1 - 0.07 13.1 1.1 3.7 7.6 0.0 3.0 2 1 1 3 3 3 0 Response regulator receiver domain cNMP_binding PF00027.24 EMG50538.1 - 0.17 11.7 4.5 0.12 12.1 0.2 3.0 3 0 0 3 3 3 0 Cyclic nucleotide-binding domain Pkinase PF00069.20 EMG50540.1 - 1.6e-71 240.5 0.2 5.2e-71 238.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50540.1 - 3.3e-34 118.1 0.0 1.7e-33 115.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG50540.1 - 0.00084 18.3 0.1 0.06 12.2 0.0 2.6 2 0 0 2 2 2 2 Kinase-like MIF4G PF02854.14 EMG50542.1 - 4.4e-42 143.8 1.0 4.4e-42 143.8 0.7 2.1 2 0 0 2 2 2 1 MIF4G domain eIF_4G1 PF12152.3 EMG50542.1 - 4.5e-25 87.3 0.3 2.5e-24 84.9 0.2 2.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 DUF3359 PF11839.3 EMG50542.1 - 0.52 10.6 6.8 1.8 8.9 4.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3359) AFT PF08731.6 EMG50543.1 - 5.8e-28 97.3 7.4 5.8e-28 97.3 5.2 5.4 6 2 0 6 6 6 1 Transcription factor AFT DBD_Tnp_Mut PF03108.10 EMG50543.1 - 0.014 14.9 1.5 0.17 11.4 1.0 2.2 1 1 0 1 1 1 0 MuDR family transposase Nramp PF01566.13 EMG50544.1 - 4.5e-87 292.1 22.0 1.8e-85 286.8 15.3 2.2 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein HAD PF12710.2 EMG50545.1 - 2.3e-15 57.2 0.1 3.4e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMG50545.1 - 1.2e-06 28.8 0.0 3.2e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EMG50545.1 - 4.3e-05 22.9 0.0 0.00018 20.9 0.0 1.8 1 1 0 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.7 EMG50545.1 - 0.00049 19.3 0.3 0.0074 15.4 0.0 2.0 2 0 0 2 2 2 1 Putative Phosphatase Ish1 PF10281.4 EMG50545.1 - 0.024 14.6 0.0 8.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Ribosomal_L12 PF00542.14 EMG50546.1 - 1.4e-20 73.0 5.3 1.4e-20 73.0 3.7 2.2 3 0 0 3 3 3 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 EMG50546.1 - 0.63 10.4 9.8 0.22 11.9 2.5 2.3 1 1 0 2 2 2 0 60s Acidic ribosomal protein TFIIS_C PF01096.13 EMG50548.1 - 1.5e-16 59.7 15.0 1.1e-14 53.8 4.4 3.0 3 0 0 3 3 3 2 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EMG50548.1 - 1.9e-14 53.0 3.9 1.9e-14 53.0 2.7 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit C1_4 PF07975.7 EMG50548.1 - 0.00084 19.2 11.9 0.15 12.0 0.2 3.2 2 1 1 3 3 3 2 TFIIH C1-like domain DZR PF12773.2 EMG50548.1 - 0.0048 16.6 0.6 0.0048 16.6 0.4 2.7 2 1 0 2 2 2 1 Double zinc ribbon Lar_restr_allev PF14354.1 EMG50548.1 - 0.012 15.8 6.0 0.78 10.0 1.2 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar Zn_ribbon_recom PF13408.1 EMG50548.1 - 0.025 14.8 4.6 0.18 12.1 0.3 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Elf1 PF05129.8 EMG50548.1 - 0.086 12.5 5.2 1.5 8.5 0.9 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like IBR PF01485.16 EMG50548.1 - 0.089 12.6 7.9 1.9 8.3 0.4 2.3 2 0 0 2 2 2 0 IBR domain zf-ribbon_3 PF13248.1 EMG50548.1 - 0.099 11.8 13.0 4.3 6.6 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-UBP PF02148.14 EMG50548.1 - 0.21 11.7 8.6 3.9 7.6 1.2 2.6 2 2 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Ogr_Delta PF04606.7 EMG50548.1 - 0.24 11.0 14.3 0.051 13.2 2.3 2.7 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger DUF2082 PF09855.4 EMG50548.1 - 0.31 10.9 0.3 0.31 10.9 0.2 3.1 2 2 1 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-FPG_IleRS PF06827.9 EMG50548.1 - 0.59 9.8 6.1 36 4.1 0.0 3.5 3 1 0 3 3 3 0 Zinc finger found in FPG and IleRS DUF3268 PF11672.3 EMG50548.1 - 0.73 9.9 6.8 2.6 8.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) UPF0547 PF10571.4 EMG50548.1 - 1 9.1 14.2 3.6 7.3 0.3 4.2 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.1 EMG50548.1 - 1.4 8.4 12.3 1.3 8.5 0.6 3.6 3 1 0 3 3 3 0 zinc-ribbon domain Ribosomal_L44 PF00935.14 EMG50548.1 - 2 8.4 0.0 2 8.4 0.0 2.6 2 2 1 3 3 3 0 Ribosomal protein L44 zf-C4_Topoisom PF01396.14 EMG50548.1 - 2.1 7.9 13.8 0.47 9.9 0.7 2.6 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Zn_Tnp_IS1595 PF12760.2 EMG50548.1 - 2.2 8.1 13.8 7.2 6.5 0.8 2.9 2 1 0 2 2 2 0 Transposase zinc-ribbon domain DUF2296 PF10058.4 EMG50548.1 - 2.3 8.0 12.9 4.5 7.0 1.2 2.8 2 1 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Zn-ribbon_8 PF09723.5 EMG50548.1 - 2.9 7.9 14.2 17 5.4 0.7 4.0 4 0 0 4 4 4 0 Zinc ribbon domain A2L_zn_ribbon PF08792.5 EMG50548.1 - 8.1 6.0 14.6 28 4.3 0.3 4.3 4 0 0 4 4 4 0 A2L zinc ribbon domain PADR1 PF08063.7 EMG50548.1 - 8.8 5.8 11.6 5.9 6.3 0.5 3.3 4 0 0 4 4 4 0 PADR1 (NUC008) domain Pkinase PF00069.20 EMG50549.1 - 2.3e-70 236.7 0.0 4.2e-70 235.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50549.1 - 1.2e-39 135.9 0.0 2e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG50549.1 - 2.2e-05 23.5 0.1 5.8e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 EMG50549.1 - 0.0088 15.3 0.7 0.069 12.4 0.0 2.4 2 1 0 2 2 2 1 PhoP regulatory network protein YrbL Peptidase_C14 PF00656.17 EMG50549.1 - 0.73 9.4 7.5 1.1 8.8 5.2 1.2 1 0 0 1 1 1 0 Caspase domain TFIIA PF03153.8 EMG50549.1 - 1.2 8.9 14.7 1.6 8.5 10.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fungal_trans PF04082.13 EMG50550.1 - 1.5e-16 60.1 1.3 2.7e-16 59.2 0.6 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG50550.1 - 3.4e-10 39.6 13.5 6.5e-10 38.7 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAC2 PF09754.4 EMG50551.1 - 4.4e-32 111.7 0.5 2.6e-30 105.9 0.3 2.0 1 1 0 1 1 1 1 PAC2 family TFIIS_C PF01096.13 EMG50552.1 - 9e-19 66.8 2.0 9e-19 66.8 1.4 2.8 4 0 0 4 4 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EMG50552.1 - 7.8e-08 31.8 8.6 3.1e-05 23.5 0.2 3.1 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit zf-ribbon_3 PF13248.1 EMG50552.1 - 0.00022 20.3 11.5 1.3 8.3 0.2 4.2 4 0 0 4 4 4 3 zinc-ribbon domain DZR PF12773.2 EMG50552.1 - 0.00027 20.6 8.4 0.031 14.1 0.2 2.9 2 1 0 2 2 2 2 Double zinc ribbon Lar_restr_allev PF14354.1 EMG50552.1 - 0.00059 20.0 7.9 0.0016 18.7 0.3 2.7 2 1 0 2 2 2 1 Restriction alleviation protein Lar Baculo_LEF5_C PF11792.3 EMG50552.1 - 0.0023 17.2 1.9 0.063 12.6 0.0 3.0 3 0 0 3 3 3 1 Baculoviridae late expression factor 5 C-terminal domain TF_Zn_Ribbon PF08271.7 EMG50552.1 - 0.0026 17.0 11.8 0.016 14.5 2.4 3.0 2 2 0 2 2 2 1 TFIIB zinc-binding Ogr_Delta PF04606.7 EMG50552.1 - 0.0047 16.5 2.8 0.0047 16.5 2.0 2.5 2 1 0 2 2 2 1 Ogr/Delta-like zinc finger Zn-ribbon_8 PF09723.5 EMG50552.1 - 0.0064 16.4 10.7 1.8 8.6 0.1 3.4 3 0 0 3 3 3 1 Zinc ribbon domain zinc_ribbon_2 PF13240.1 EMG50552.1 - 0.0067 15.8 17.4 1.4 8.5 1.0 3.5 3 1 0 3 3 3 2 zinc-ribbon domain zf-PHD-like PF15446.1 EMG50552.1 - 0.0099 15.1 1.1 0.0099 15.1 0.7 1.6 1 1 1 2 2 2 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 EMG50552.1 - 0.01 15.5 3.6 0.37 10.5 0.2 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-TFIIB PF13453.1 EMG50552.1 - 0.017 14.2 0.8 0.044 12.9 0.6 1.7 1 0 0 1 1 1 0 Transcription factor zinc-finger zf-C4_Topoisom PF01396.14 EMG50552.1 - 0.019 14.4 3.3 0.019 14.4 2.3 3.0 2 2 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Terminase_GpA PF05876.7 EMG50552.1 - 0.021 13.1 0.4 0.028 12.7 0.3 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) DUF2387 PF09526.5 EMG50552.1 - 0.038 13.8 1.4 0.053 13.4 0.2 1.8 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) K167R PF08065.7 EMG50552.1 - 0.072 13.1 0.1 0.089 12.9 0.1 1.1 1 0 0 1 1 1 0 K167R (NUC007) repeat DUF523 PF04463.7 EMG50552.1 - 0.081 12.6 0.2 0.12 12.1 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF523) Zn_Tnp_IS1595 PF12760.2 EMG50552.1 - 0.086 12.6 7.9 0.06 13.1 1.4 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Elf1 PF05129.8 EMG50552.1 - 0.089 12.5 7.0 0.19 11.4 0.3 2.5 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.1 EMG50552.1 - 0.11 12.1 8.6 5.5 6.7 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain zf-C3HC4_3 PF13920.1 EMG50552.1 - 0.12 12.0 3.5 7.5 6.3 0.2 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF2072 PF09845.4 EMG50552.1 - 0.12 12.2 0.1 0.12 12.2 0.1 2.9 1 1 2 3 3 3 0 Zn-ribbon containing protein (DUF2072) OrfB_Zn_ribbon PF07282.6 EMG50552.1 - 0.14 11.8 8.1 3.6 7.3 2.0 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Nop10p PF04135.7 EMG50552.1 - 0.16 11.6 1.8 0.22 11.2 0.2 2.1 2 0 0 2 2 1 0 Nucleolar RNA-binding protein, Nop10p family zinc_ribbon_5 PF13719.1 EMG50552.1 - 0.24 11.0 9.0 6 6.5 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain IBR PF01485.16 EMG50552.1 - 0.26 11.1 7.9 6.1 6.8 1.7 2.7 2 1 0 2 2 2 0 IBR domain DUF3268 PF11672.3 EMG50552.1 - 0.28 11.2 2.7 3.4 7.7 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) zf-CHY PF05495.7 EMG50552.1 - 0.32 11.1 6.8 1.6 8.9 0.1 2.8 2 1 0 2 2 2 0 CHY zinc finger zf-DNA_Pol PF08996.5 EMG50552.1 - 0.33 10.2 5.2 0.097 12.0 0.7 2.0 1 1 0 2 2 2 0 DNA Polymerase alpha zinc finger zf-HYPF PF07503.7 EMG50552.1 - 0.46 9.9 0.2 0.46 9.9 0.1 3.3 4 0 0 4 4 3 0 HypF finger HypA PF01155.14 EMG50552.1 - 0.62 9.7 8.5 98 2.6 0.1 2.9 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family RRN7 PF11781.3 EMG50552.1 - 0.64 9.5 8.3 31 4.1 0.0 4.2 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF3797 PF12677.2 EMG50552.1 - 0.84 9.3 9.0 10 5.8 4.0 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3797) PolC_DP2 PF03833.8 EMG50552.1 - 1.6 6.2 3.9 0.58 7.7 0.6 1.6 1 1 1 2 2 2 0 DNA polymerase II large subunit DP2 zf-HIT PF04438.11 EMG50552.1 - 1.8 8.3 13.9 8.4 6.1 0.5 4.0 4 0 0 4 4 4 0 HIT zinc finger A2L_zn_ribbon PF08792.5 EMG50552.1 - 2.1 7.8 13.0 5 6.7 1.2 3.4 3 1 0 3 3 3 0 A2L zinc ribbon domain RecR PF02132.10 EMG50552.1 - 2.2 7.7 11.1 0.17 11.3 0.4 3.1 3 0 0 3 3 3 0 RecR protein UPF0547 PF10571.4 EMG50552.1 - 2.7 7.7 10.6 13 5.5 0.2 3.5 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Rpr2 PF04032.11 EMG50552.1 - 2.7 7.9 7.5 61 3.5 5.2 2.5 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C3HC4_4 PF15227.1 EMG50552.1 - 3.1 7.7 6.0 4.3 7.3 0.9 2.8 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Rubredoxin PF00301.15 EMG50552.1 - 3.3 7.6 11.7 14 5.6 0.2 3.9 3 1 1 4 4 4 0 Rubredoxin zf-ISL3 PF14690.1 EMG50552.1 - 3.4 7.7 9.8 3.7 7.6 0.1 3.5 3 1 1 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_ribbon_recom PF13408.1 EMG50552.1 - 3.5 7.9 13.3 6.7 7.0 0.2 3.4 2 2 1 3 3 3 0 Recombinase zinc beta ribbon domain DUF3716 PF12511.3 EMG50552.1 - 3.6 7.2 6.1 0.36 10.4 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) zf-Mss51 PF13824.1 EMG50552.1 - 4.3 7.2 9.1 9.2 6.2 1.6 2.8 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-Di19 PF05605.7 EMG50552.1 - 4.6 7.4 10.2 1.7 8.8 0.3 3.3 3 1 1 4 4 3 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 EMG50552.1 - 7.2 7.1 16.4 0.39 11.0 0.9 3.9 3 1 1 4 4 4 0 Zinc-finger double domain zf-C2H2 PF00096.21 EMG50552.1 - 7.5 7.1 14.9 0.69 10.3 1.0 3.9 4 0 0 4 4 3 0 Zinc finger, C2H2 type zf-AN1 PF01428.11 EMG50552.1 - 7.9 6.4 9.5 28 4.6 0.2 3.4 3 1 1 4 4 4 0 AN1-like Zinc finger zf-MYND PF01753.13 EMG50552.1 - 8.3 6.3 8.5 11 5.9 0.9 2.5 2 1 0 2 2 2 0 MYND finger CpXC PF14353.1 EMG50552.1 - 9.8 6.1 10.3 1.1 9.1 0.1 2.9 2 2 1 4 4 2 0 CpXC protein HEAT_2 PF13646.1 EMG50553.1 - 1.8e-34 117.8 3.1 1e-16 60.9 0.1 3.5 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.11 EMG50553.1 - 3.1e-22 76.7 0.4 2.1e-06 27.6 0.0 6.7 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT PF02985.17 EMG50553.1 - 2.3e-14 52.1 0.3 0.083 13.0 0.0 6.0 6 0 0 6 6 6 4 HEAT repeat HEAT_EZ PF13513.1 EMG50553.1 - 5.9e-14 52.0 1.1 0.013 15.9 0.0 5.4 3 1 2 5 5 5 4 HEAT-like repeat Arm PF00514.18 EMG50553.1 - 0.01 15.6 0.1 0.3 10.9 0.0 3.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 EMG50553.1 - 0.12 12.4 0.4 0.67 9.9 0.1 2.5 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Macro PF01661.16 EMG50554.1 - 2.7e-32 111.1 0.2 5.2e-32 110.2 0.1 1.5 1 0 0 1 1 1 1 Macro domain Flavin_Reduct PF01613.13 EMG50555.1 - 1e-20 74.1 0.0 1.5e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DHquinase_II PF01220.14 EMG50556.1 - 1.1e-55 186.7 0.5 1.3e-55 186.6 0.3 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Dioxygenase_C PF00775.16 EMG50557.1 - 4.8e-54 182.4 0.0 6.4e-54 181.9 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EMG50557.1 - 3.6e-16 58.9 0.0 6.6e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EMG50557.1 - 0.0001 22.2 0.0 0.00024 21.0 0.0 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CoA_trans PF01144.18 EMG50558.1 - 2.9e-97 324.0 0.8 4.7e-56 189.3 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Epimerase PF01370.16 EMG50559.1 - 4.3e-26 91.7 0.0 5.6e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMG50559.1 - 8.6e-15 54.1 0.0 1.1e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMG50559.1 - 6.2e-13 49.1 0.0 9.2e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMG50559.1 - 1.8e-12 46.7 0.0 1.1e-10 40.8 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EMG50559.1 - 2.2e-10 40.6 0.0 1.6e-09 37.9 0.0 2.3 3 0 0 3 3 3 1 short chain dehydrogenase NmrA PF05368.8 EMG50559.1 - 1.4e-07 30.9 0.6 8.9e-06 25.1 0.1 2.5 1 1 0 2 2 2 1 NmrA-like family KR PF08659.5 EMG50559.1 - 3.2e-05 23.6 0.0 0.00023 20.8 0.0 2.3 2 1 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EMG50559.1 - 0.00038 19.4 0.0 0.00063 18.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 EMG50559.1 - 0.0058 17.0 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 EMG50559.1 - 0.063 12.1 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain Semialdhyde_dh PF01118.19 EMG50559.1 - 0.086 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EMG50559.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sigma54_activ_2 PF14532.1 EMG50559.1 - 0.13 12.3 0.0 0.4 10.7 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Cpn60_TCP1 PF00118.19 EMG50560.1 - 1e-144 482.7 2.9 1.2e-144 482.5 2.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Epimerase PF01370.16 EMG50561.1 - 6.9e-19 68.2 0.0 9.2e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMG50561.1 - 1e-15 57.1 0.0 1.5e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMG50561.1 - 2.7e-12 46.1 0.0 1.4e-11 43.8 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EMG50561.1 - 5.5e-09 36.2 0.3 2.5e-08 34.1 0.2 1.9 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMG50561.1 - 4.4e-06 26.7 0.0 8.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMG50561.1 - 0.0008 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EMG50561.1 - 0.001 18.3 0.1 0.0028 16.9 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 EMG50561.1 - 0.0032 16.4 0.0 0.0047 15.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 EMG50561.1 - 0.048 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 EMG50562.1 - 3.5e-15 56.0 0.0 4.8e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMG50562.1 - 2.2e-12 46.3 0.0 3.4e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMG50562.1 - 1.5e-09 38.1 0.0 5.8e-09 36.2 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMG50562.1 - 1.1e-08 34.3 0.0 2.4e-08 33.2 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EMG50562.1 - 0.0019 18.1 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EMG50562.1 - 0.0031 16.8 0.0 0.17 11.1 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 EMG50562.1 - 0.0099 14.8 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 EMG50562.1 - 0.037 14.4 0.0 0.08 13.3 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1771 PF08590.5 EMG50563.1 - 1.5e-24 85.7 11.1 2.7e-24 84.9 7.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 EMG50563.1 - 8.5e-16 57.9 0.1 2.5e-15 56.4 0.1 1.8 1 0 0 1 1 1 1 Smr domain PMC2NT PF08066.7 EMG50563.1 - 0.055 13.7 3.1 0.34 11.2 0.7 2.6 1 1 1 2 2 2 0 PMC2NT (NUC016) domain Seryl_tRNA_N PF02403.17 EMG50563.1 - 0.072 13.1 8.4 0.12 12.3 5.5 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF643 PF04867.7 EMG50563.1 - 0.14 12.5 2.7 0.24 11.8 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF643) DUF2992 PF11208.3 EMG50563.1 - 0.26 11.1 6.9 0.45 10.4 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF883 PF05957.8 EMG50563.1 - 7.4 7.0 7.0 16 6.0 2.1 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Ras PF00071.17 EMG50564.1 - 8.1e-52 174.8 0.3 9.9e-52 174.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMG50564.1 - 1.3e-20 74.0 0.1 2e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMG50564.1 - 2.4e-17 62.7 0.1 2.7e-17 62.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMG50564.1 - 4.3e-10 39.1 0.2 5.5e-10 38.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMG50564.1 - 1.3e-08 34.5 0.2 1.8e-07 30.7 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMG50564.1 - 9e-07 28.8 0.1 1.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EMG50564.1 - 2.8e-05 23.7 0.3 0.0037 16.8 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EMG50564.1 - 0.00029 20.9 0.1 0.0011 19.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 EMG50564.1 - 0.0004 19.6 0.2 0.00067 18.9 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 EMG50564.1 - 0.0005 19.8 0.1 0.00052 19.7 0.0 1.4 1 1 0 1 1 1 1 Archaeal ATPase PduV-EutP PF10662.4 EMG50564.1 - 0.00067 19.1 0.2 0.0057 16.1 0.1 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EMG50564.1 - 0.0015 18.1 0.0 0.0032 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EMG50564.1 - 0.0019 17.3 0.0 0.0076 15.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NACHT PF05729.7 EMG50564.1 - 0.0025 17.4 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_5 PF07728.9 EMG50564.1 - 0.0034 17.0 0.2 0.047 13.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMG50564.1 - 0.0055 16.7 0.0 0.012 15.5 0.0 1.5 2 0 0 2 2 1 1 AAA ATPase domain Septin PF00735.13 EMG50564.1 - 0.0096 14.9 0.4 0.02 13.9 0.1 1.6 2 0 0 2 2 2 1 Septin MobB PF03205.9 EMG50564.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.5 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EMG50564.1 - 0.016 14.9 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 NTPase AAA_10 PF12846.2 EMG50564.1 - 0.021 14.2 0.1 0.039 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain NB-ARC PF00931.17 EMG50564.1 - 0.023 13.5 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.1 EMG50564.1 - 0.033 14.0 0.3 0.08 12.8 0.2 1.9 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EMG50564.1 - 0.057 12.9 0.0 0.12 11.9 0.0 1.2 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PRK PF00485.13 EMG50564.1 - 0.061 12.8 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 EMG50564.1 - 0.076 13.2 0.1 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 RNA helicase cobW PF02492.14 EMG50564.1 - 0.081 12.3 0.4 0.23 10.8 0.1 1.8 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.13 EMG50564.1 - 0.1 11.8 0.2 10 5.3 0.1 2.7 2 1 1 3 3 3 0 Ferrous iron transport protein B ABC_tran PF00005.22 EMG50564.1 - 0.12 12.6 0.9 0.16 12.2 0.6 1.6 1 1 0 1 1 1 0 ABC transporter AAA PF00004.24 EMG50564.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.15 EMG50564.1 - 0.27 9.8 6.3 0.16 10.6 0.2 2.4 1 1 1 2 2 2 0 G-protein alpha subunit MCM PF00493.18 EMG50565.1 - 1.9e-127 424.6 0.2 2.8e-127 424.0 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EMG50565.1 - 4.4e-22 78.8 0.0 1.3e-21 77.2 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EMG50565.1 - 1.1e-07 31.2 0.0 9.4e-07 28.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EMG50565.1 - 0.0017 17.8 0.0 0.0062 16.0 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 EMG50565.1 - 0.0017 17.9 0.0 0.0036 16.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMG50565.1 - 0.056 13.1 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Cwf_Cwc_15 PF04889.7 EMG50565.1 - 0.086 12.5 7.5 0.16 11.6 5.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CBF PF03914.12 EMG50566.1 - 6.2e-43 146.0 2.6 6.2e-43 146.0 1.8 1.9 2 0 0 2 2 2 1 CBF/Mak21 family FAT PF02259.18 EMG50567.1 - 1e-138 462.1 4.4 1e-138 462.1 3.1 3.1 3 1 0 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.22 EMG50567.1 - 1.9e-60 204.3 0.1 5.8e-60 202.6 0.1 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EMG50567.1 - 1.3e-58 197.4 8.8 1.6e-58 197.1 0.6 4.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EMG50567.1 - 7.6e-41 138.2 8.2 9.2e-41 137.9 1.2 3.6 3 0 0 3 3 3 1 Rapamycin binding domain FATC PF02260.15 EMG50567.1 - 6.8e-18 63.8 0.1 1.6e-17 62.5 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.1 EMG50567.1 - 7.1e-16 58.2 4.2 0.021 15.0 0.0 9.1 8 2 3 11 11 10 3 HEAT repeats HEAT_EZ PF13513.1 EMG50567.1 - 5.3e-13 49.0 4.9 0.00013 22.2 0.0 9.7 8 1 4 12 12 10 3 HEAT-like repeat HEAT PF02985.17 EMG50567.1 - 1.3e-12 46.6 1.8 0.0065 16.4 0.0 8.5 7 0 0 7 7 7 2 HEAT repeat CLASP_N PF12348.3 EMG50567.1 - 1.5e-08 34.3 0.2 0.063 12.6 0.0 5.1 4 2 0 5 5 5 3 CLASP N terminal TPR_19 PF14559.1 EMG50567.1 - 0.00027 21.2 0.4 7.9 6.8 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMG50567.1 - 0.00056 20.5 0.0 1.6 9.5 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMG50567.1 - 0.019 15.5 0.2 5.5 7.9 0.0 4.6 4 1 1 5 5 3 0 Tetratricopeptide repeat DUF1104 PF06518.6 EMG50567.1 - 0.14 12.3 0.0 0.14 12.3 0.0 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF1104) Actin PF00022.14 EMG50568.1 - 9.1e-92 307.4 0.0 1.9e-91 306.4 0.0 1.4 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EMG50568.1 - 0.0024 16.5 0.0 0.1 11.1 0.0 2.3 2 1 0 2 2 2 2 MreB/Mbl protein DUF498 PF04430.9 EMG50570.1 - 1.9e-18 66.0 0.0 2.5e-18 65.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) DUF469 PF04320.9 EMG50571.1 - 0.2 12.4 1.7 0.42 11.4 1.1 1.6 1 0 0 1 1 1 0 Protein with unknown function (DUF469) Pil1 PF13805.1 EMG50572.1 - 3.4e-153 508.4 0.4 4e-153 508.2 0.3 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 EMG50572.1 - 0.064 12.5 2.4 0.1 11.9 1.7 1.4 1 0 0 1 1 1 0 FAM92 protein V_ATPase_I PF01496.14 EMG50572.1 - 0.11 10.3 2.0 0.14 9.9 1.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RasGEF PF00617.14 EMG50573.1 - 5e-39 133.9 0.1 1.4e-38 132.5 0.1 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EMG50573.1 - 6.2e-12 45.5 4.2 6.2e-12 45.5 2.9 3.1 4 0 0 4 4 4 1 RasGEF N-terminal motif Ribosomal_L5_C PF00673.16 EMG50574.1 - 1.8e-23 82.0 0.1 2.7e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EMG50574.1 - 2e-19 69.1 1.6 3.4e-19 68.3 0.0 2.2 3 0 0 3 3 3 1 Ribosomal protein L5 Proteasome PF00227.21 EMG50575.1 - 3.5e-47 160.1 0.8 4.7e-47 159.7 0.1 1.6 2 0 0 2 2 2 1 Proteasome subunit Fork_head PF00250.13 EMG50575.1 - 1.9e-14 53.4 0.3 4.7e-14 52.1 0.2 1.7 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EMG50575.1 - 6.7e-10 38.9 0.2 1.7e-09 37.6 0.2 1.8 1 0 0 1 1 1 1 FHA domain Cellulase PF00150.13 EMG50576.1 - 5.8e-07 28.9 4.5 8.9e-06 25.1 3.1 2.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SLX9 PF15341.1 EMG50577.1 - 3.2e-13 50.1 16.8 3.2e-13 50.1 11.6 2.0 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 Cu_amine_oxid PF01179.15 EMG50579.1 - 1.1e-161 538.1 0.1 1.3e-161 537.9 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EMG50579.1 - 0.00074 19.5 0.2 0.002 18.1 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cofilin_ADF PF00241.15 EMG50580.1 - 4.8e-28 97.5 0.2 2.2e-13 50.1 0.0 2.4 2 1 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein PolyG_pol PF01518.11 EMG50580.1 - 0.043 12.2 0.0 0.062 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma NS protein Asparaginase PF00710.15 EMG50580.1 - 0.12 11.2 0.1 0.18 10.6 0.1 1.3 1 0 0 1 1 1 0 Asparaginase zf-RING_2 PF13639.1 EMG50581.1 - 7.2e-10 38.5 29.4 9.2e-08 31.8 6.2 2.3 2 0 0 2 2 2 2 Ring finger domain PHD PF00628.24 EMG50581.1 - 0.00064 19.3 13.5 0.00064 19.3 9.4 3.0 2 1 1 3 3 3 1 PHD-finger zf-C3HC4_3 PF13920.1 EMG50581.1 - 0.011 15.4 8.4 0.011 15.4 5.8 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.1 EMG50581.1 - 0.011 15.0 7.5 0.011 15.0 5.2 2.8 3 1 1 4 4 4 0 PHD-finger zf-rbx1 PF12678.2 EMG50581.1 - 1.4 9.0 25.4 0.048 13.7 4.8 3.2 2 1 0 2 2 2 0 RING-H2 zinc finger C1_1 PF00130.17 EMG50581.1 - 8 6.2 25.0 0.2 11.4 3.4 3.3 2 2 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.1 EMG50581.1 - 8.1 6.5 33.3 1.9 8.5 7.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMG50581.1 - 8.3 6.2 30.6 0.4 10.4 6.9 2.3 2 0 0 2 2 2 0 zinc-RING finger domain BCAS2 PF05700.6 EMG50582.1 - 2.2e-06 27.2 17.2 0.014 14.8 11.9 2.4 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Salt_tol_Pase PF09506.5 EMG50582.1 - 0.01 14.4 0.7 0.01 14.4 0.5 1.7 2 0 0 2 2 2 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) RICH PF05062.7 EMG50582.1 - 0.084 13.0 4.2 0.32 11.1 0.6 2.6 1 1 1 2 2 2 0 RICH domain AAA_23 PF13476.1 EMG50582.1 - 5.2 7.3 13.9 10 6.3 9.6 1.5 1 1 0 1 1 1 0 AAA domain SH3_1 PF00018.23 EMG50583.1 - 3e-05 23.3 0.0 0.00016 20.9 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EMG50583.1 - 0.00012 21.5 0.0 0.01 15.3 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain Aminotran_1_2 PF00155.16 EMG50584.1 - 1.7e-74 250.9 0.0 2e-74 250.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Rxt3 PF08642.5 EMG50585.1 - 1.3e-29 102.7 0.0 1.3e-29 102.7 0.0 2.9 2 1 0 2 2 2 1 Histone deacetylation protein Rxt3 Aminotran_3 PF00202.16 EMG50586.1 - 2.4e-79 266.6 0.1 2.8e-79 266.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EMG50586.1 - 0.0026 16.9 0.0 0.0045 16.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DUF1746 PF08508.5 EMG50587.1 - 4.1e-33 113.7 0.8 5.6e-33 113.3 0.5 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) RNA_pol_A_bac PF01000.21 EMG50588.1 - 2.6e-26 91.9 0.0 4.8e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EMG50588.1 - 2.6e-15 55.3 0.0 5.2e-15 54.3 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Hormone_4 PF00220.12 EMG50588.1 - 0.16 11.7 1.0 0.38 10.5 0.7 1.7 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain Pkinase PF00069.20 EMG50590.1 - 2.5e-39 135.0 0.0 1.2e-22 80.3 0.0 3.8 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50590.1 - 7.5e-16 57.9 0.0 6.8e-12 44.9 0.0 3.4 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EMG50590.1 - 0.0049 16.6 0.0 0.0094 15.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Bot1p PF12298.3 EMG50591.1 - 3.5e-51 173.5 0.5 6.3e-51 172.7 0.3 1.4 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein EMP24_GP25L PF01105.19 EMG50591.1 - 1.4e-48 165.0 2.0 3.6e-48 163.7 1.4 1.7 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PIG-P PF08510.7 EMG50592.1 - 1.5e-34 118.2 3.1 1.9e-34 118.0 2.1 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.7 EMG50592.1 - 0.00014 22.0 3.4 0.00021 21.5 2.4 1.3 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) HEAT_EZ PF13513.1 EMG50593.1 - 3.7e-21 74.9 1.2 1.3e-10 41.4 0.0 7.7 9 0 0 9 9 9 2 HEAT-like repeat HEAT PF02985.17 EMG50593.1 - 7.9e-20 69.1 7.5 0.0055 16.6 0.0 11.9 13 0 0 13 13 13 4 HEAT repeat HEAT_2 PF13646.1 EMG50593.1 - 8.8e-19 67.5 0.0 2.4e-06 27.7 0.0 7.4 5 3 2 7 7 7 4 HEAT repeats Vac14_Fab1_bd PF12755.2 EMG50593.1 - 1.6e-06 28.3 1.4 0.0091 16.3 0.0 5.0 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 EMG50593.1 - 0.0014 18.4 2.0 0.014 15.2 0.0 3.6 5 0 0 5 5 5 1 Importin-beta N-terminal domain Arm PF00514.18 EMG50593.1 - 0.031 14.0 5.8 0.73 9.7 0.0 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Xpo1 PF08389.7 EMG50593.1 - 0.95 9.3 13.7 2.5 8.0 4.1 4.8 3 2 1 4 4 4 0 Exportin 1-like protein PBP1_TM PF14812.1 EMG50593.1 - 1.2 9.5 8.8 2.8 8.2 6.1 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_L28 PF00830.14 EMG50594.1 - 3.1e-15 55.7 1.1 5.7e-15 54.8 0.7 1.5 1 0 0 1 1 1 1 Ribosomal L28 family Ded_cyto PF06920.8 EMG50595.1 - 3.6e-22 78.5 0.0 8.2e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 Dedicator of cytokinesis AA_permease PF00324.16 EMG50596.1 - 5.3e-75 252.5 46.7 2.4e-74 250.4 32.4 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG50596.1 - 2.8e-26 92.0 41.6 5.5e-26 91.0 28.8 1.5 1 1 0 1 1 1 1 Amino acid permease DUF2417 PF10329.4 EMG50596.1 - 5.3 6.3 11.0 16 4.7 7.4 1.9 2 0 0 2 2 2 0 Region of unknown function (DUF2417) DUF1640 PF07798.6 EMG50597.1 - 2.7e-09 37.3 3.2 8.4e-09 35.7 2.2 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Ubie_methyltran PF01209.13 EMG50598.1 - 1.1e-88 296.2 0.0 1.3e-88 296.0 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EMG50598.1 - 1.3e-10 41.0 0.0 2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMG50598.1 - 1e-09 38.7 0.0 2e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMG50598.1 - 1.5e-09 38.2 0.0 2.4e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMG50598.1 - 1.2e-06 28.3 0.0 1.9e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMG50598.1 - 2.1e-06 28.0 0.0 3.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMG50598.1 - 0.00087 19.3 0.0 0.0029 17.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMG50598.1 - 0.003 18.1 0.0 0.0055 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EMG50598.1 - 0.064 12.8 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Mito_fiss_reg PF05308.6 EMG50598.1 - 0.068 12.5 1.8 0.099 12.0 1.3 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator PK PF00224.16 EMG50599.1 - 4.4e-171 568.1 3.2 5.6e-171 567.8 2.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EMG50599.1 - 7.5e-32 109.3 0.1 3.7e-31 107.1 0.0 2.2 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EMG50599.1 - 9.2e-05 21.4 0.7 0.00018 20.4 0.1 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family DnaJ PF00226.26 EMG50600.1 - 4.1e-08 32.8 0.1 8.4e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EMG50600.1 - 1.3e-05 25.0 0.8 9.3e-05 22.2 0.6 2.2 1 1 0 1 1 1 1 Pam16 AAA PF00004.24 EMG50601.1 - 2e-56 189.7 0.0 2.9e-43 147.2 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMG50601.1 - 1.4e-05 25.8 0.3 0.0019 19.0 0.0 3.6 2 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EMG50601.1 - 3e-05 24.0 0.5 0.024 14.6 0.0 3.5 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EMG50601.1 - 3.9e-05 22.8 0.0 0.0015 17.6 0.0 2.9 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EMG50601.1 - 7.1e-05 22.7 0.0 0.005 16.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 EMG50601.1 - 0.00011 21.7 0.2 0.0033 16.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 EMG50601.1 - 0.00032 19.6 0.0 0.00067 18.6 0.0 1.5 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_22 PF13401.1 EMG50601.1 - 0.00037 20.6 0.2 0.0062 16.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EMG50601.1 - 0.00064 19.6 0.0 0.078 12.8 0.0 3.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EMG50601.1 - 0.001 19.2 0.0 0.011 15.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.12 EMG50601.1 - 0.0013 18.2 0.0 0.003 16.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein KaiC PF06745.8 EMG50601.1 - 0.0052 15.9 0.0 0.015 14.4 0.0 1.7 1 0 0 1 1 1 1 KaiC AAA_5 PF07728.9 EMG50601.1 - 0.0068 16.1 0.0 0.04 13.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EMG50601.1 - 0.0082 14.9 0.0 0.02 13.5 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EMG50601.1 - 0.011 15.4 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 EMG50601.1 - 0.013 14.6 0.0 0.037 13.2 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EMG50601.1 - 0.025 14.4 0.0 0.31 10.9 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.1 EMG50601.1 - 0.028 14.3 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EMG50601.1 - 0.031 14.5 3.0 0.081 13.2 0.0 3.3 3 2 0 3 3 3 0 AAA domain AAA_24 PF13479.1 EMG50601.1 - 0.034 13.7 0.6 0.18 11.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EMG50601.1 - 0.05 13.2 0.1 0.92 9.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 EMG50601.1 - 0.053 12.7 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EMG50601.1 - 0.072 12.7 0.0 2.3 7.8 0.0 2.7 3 0 0 3 3 3 0 NACHT domain Ribosomal_L31e PF01198.14 EMG50602.1 - 1e-35 121.2 1.9 1.2e-35 121.0 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e COG5 PF10392.4 EMG50604.1 - 0.5 10.3 9.3 0.11 12.5 3.4 2.0 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Syntaxin-6_N PF09177.6 EMG50604.1 - 0.95 9.9 5.5 0.9 9.9 1.3 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Ribosomal_L36e PF01158.13 EMG50605.1 - 1.6e-36 124.1 8.4 1.7e-36 124.0 5.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DUF4050 PF13259.1 EMG50606.1 - 8e-19 67.7 5.2 8e-19 67.7 3.6 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF4050) DUF434 PF04256.7 EMG50606.1 - 0.064 12.6 0.2 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF434) ArfGap PF01412.13 EMG50606.1 - 0.22 11.3 2.5 15 5.3 0.0 2.9 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf Angiomotin_C PF12240.3 EMG50606.1 - 2.2 7.7 5.6 8.6 5.8 2.4 2.6 2 0 0 2 2 2 0 Angiomotin C terminal DUF3439 PF11921.3 EMG50606.1 - 4.6 7.0 8.4 7.9 6.2 1.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) PRCC PF10253.4 EMG50607.1 - 0.034 14.8 3.5 0.05 14.2 2.4 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting FemAB PF02388.11 EMG50607.1 - 0.06 12.0 3.0 0.087 11.5 2.1 1.2 1 0 0 1 1 1 0 FemAB family DUF2797 PF10977.3 EMG50607.1 - 0.077 12.6 0.5 0.12 12.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Med1 PF10744.4 EMG50608.1 - 1.4e-60 205.1 13.8 1.4e-60 205.1 9.6 2.1 2 0 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 EF-hand_3 PF09069.6 EMG50608.1 - 0.009 16.0 0.0 0.15 12.1 0.0 2.8 1 1 2 3 3 3 1 EF-hand MAP PF03642.8 EMG50608.1 - 0.041 14.1 1.2 0.27 11.4 0.3 2.8 2 0 0 2 2 2 0 MAP domain IF-2B PF01008.12 EMG50609.1 - 3e-59 200.3 4.0 2.2e-58 197.4 2.8 1.9 1 1 0 1 1 1 1 Initiation factor 2 subunit family ABC_sub_bind PF04392.7 EMG50609.1 - 0.00056 18.9 0.2 0.00056 18.9 0.2 1.8 2 0 0 2 2 2 1 ABC transporter substrate binding protein Fes1 PF08609.5 EMG50609.1 - 0.089 13.2 5.5 0.82 10.1 0.5 2.4 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 HSP20 PF00011.16 EMG50610.1 - 0.0033 17.2 0.1 0.036 13.9 0.1 2.0 2 0 0 2 2 2 1 Hsp20/alpha crystallin family CS PF04969.11 EMG50610.1 - 0.12 12.9 0.0 0.31 11.6 0.0 1.8 1 1 0 1 1 1 0 CS domain LRR_4 PF12799.2 EMG50611.1 - 4.2e-45 150.7 48.9 1.8e-11 43.4 1.7 8.2 6 2 4 10 10 10 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMG50611.1 - 5.3e-23 80.5 46.1 9.2e-08 31.7 2.1 6.0 2 2 5 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 EMG50611.1 - 5.7e-13 46.9 42.8 0.03 14.3 0.4 10.8 9 1 0 9 9 9 5 Leucine Rich Repeat LRR_9 PF14580.1 EMG50611.1 - 1.4e-11 44.2 18.0 9.3e-08 31.8 2.7 3.4 1 1 2 3 3 3 3 Leucine-rich repeat LRR_7 PF13504.1 EMG50611.1 - 4e-10 38.2 28.8 0.83 10.1 0.1 10.8 10 2 0 10 10 10 5 Leucine rich repeat LRR_6 PF13516.1 EMG50611.1 - 8.2e-10 37.7 38.5 0.33 11.1 0.2 11.0 8 2 3 11 11 11 6 Leucine Rich repeat PP-binding PF00550.20 EMG50612.1 - 1.4e-11 44.4 0.5 2e-11 43.9 0.3 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EMG50612.1 - 9.9e-06 25.5 0.5 2.4e-05 24.3 0.3 1.6 1 1 1 2 2 2 1 Acyl-carrier DUF1493 PF07377.7 EMG50612.1 - 0.023 14.7 0.1 0.032 14.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Ded_cyto PF06920.8 EMG50613.1 - 3.1e-24 85.2 0.1 1.1e-23 83.4 0.0 2.0 2 0 0 2 2 2 1 Dedicator of cytokinesis Phosphodiest PF01663.17 EMG50615.1 - 1.8e-13 50.5 0.2 3.4e-13 49.6 0.2 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EMG50615.1 - 2.6e-05 23.7 0.3 4.3e-05 23.0 0.2 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EMG50615.1 - 0.00024 20.3 0.5 0.00048 19.4 0.1 1.7 2 0 0 2 2 2 1 Sulfatase Cellulase PF00150.13 EMG50615.1 - 0.17 11.0 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_47 PF01532.15 EMG50616.1 - 2.2e-125 418.8 0.3 2.7e-125 418.5 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF3445 PF11927.3 EMG50617.1 - 3.6e-71 239.4 0.1 4.3e-71 239.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) adh_short PF00106.20 EMG50618.1 - 1.5e-26 93.3 0.0 2.2e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMG50618.1 - 1.2e-18 67.7 0.0 1.6e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMG50618.1 - 5.5e-10 39.1 0.0 9.1e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EMG50618.1 - 1.8e-07 30.5 0.0 3.9e-05 22.9 0.0 2.6 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EMG50618.1 - 2.2e-06 27.3 0.0 7e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EMG50618.1 - 0.034 13.9 0.0 0.082 12.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF2665 PF11654.3 EMG50618.1 - 0.12 11.9 0.1 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2665) DUF1399 PF07173.7 EMG50619.1 - 3.5e-35 121.2 1.3 1.1e-31 109.8 0.2 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1399) Pkinase PF00069.20 EMG50620.1 - 1.7e-67 227.3 0.0 3e-67 226.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50620.1 - 4.6e-28 97.9 0.0 7.5e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EMG50620.1 - 2.3e-11 44.0 0.2 2.3e-11 44.0 0.1 2.6 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMG50620.1 - 7.1e-10 38.3 0.0 2.3e-09 36.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 EMG50620.1 - 1.6e-05 24.6 0.1 0.00026 20.7 0.0 2.8 1 1 0 1 1 1 1 C2 domain APH PF01636.18 EMG50620.1 - 0.12 12.1 0.1 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EMG50620.1 - 0.12 11.6 0.0 0.31 10.3 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Peptidase_M1 PF01433.15 EMG50620.1 - 0.35 9.8 7.4 0.59 9.1 5.1 1.2 1 0 0 1 1 1 0 Peptidase family M1 zf-met PF12874.2 EMG50621.1 - 1.9e-05 24.7 0.0 3.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMG50621.1 - 0.0019 18.2 0.0 0.0034 17.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EMG50621.1 - 0.021 15.1 0.1 0.042 14.2 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type AKAP95 PF04988.7 EMG50621.1 - 0.056 13.2 0.0 0.056 13.2 0.0 2.2 1 1 1 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.2 EMG50621.1 - 0.11 12.6 1.3 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Anp1 PF03452.9 EMG50621.1 - 0.13 11.3 4.0 0.19 10.8 2.8 1.2 1 0 0 1 1 1 0 Anp1 DDHD PF02862.12 EMG50621.1 - 0.17 11.6 2.3 0.21 11.3 1.6 1.2 1 0 0 1 1 1 0 DDHD domain TPX2 PF06886.6 EMG50621.1 - 1.1 9.3 15.7 2 8.5 10.9 1.4 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) TMEM237 PF15383.1 EMG50621.1 - 1.4 7.9 5.2 1.9 7.5 3.0 1.6 2 0 0 2 2 2 0 Transmembrane protein 237 DUF4140 PF13600.1 EMG50621.1 - 1.8 9.0 6.2 0.52 10.7 2.3 1.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Pro_isomerase PF00160.16 EMG50623.1 - 5.4e-46 156.6 0.1 6.6e-46 156.3 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD adh_short PF00106.20 EMG50624.1 - 9.6e-27 93.9 0.0 1.4e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMG50624.1 - 5.2e-20 72.2 0.0 7e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMG50624.1 - 8.6e-10 38.5 0.0 2.6e-09 37.0 0.0 1.7 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 EMG50624.1 - 1.1e-07 31.3 0.0 1.9e-06 27.2 0.0 2.4 2 1 0 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EMG50624.1 - 2.6e-05 23.7 0.0 9.2e-05 21.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EMG50624.1 - 0.035 13.8 0.0 0.091 12.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF904 PF06005.7 EMG50625.1 - 0.00035 20.8 0.6 0.00035 20.8 0.4 3.6 2 1 0 2 2 1 1 Protein of unknown function (DUF904) Striatin PF08232.7 EMG50625.1 - 0.0035 17.6 0.5 0.0035 17.6 0.3 3.1 1 1 1 2 2 1 1 Striatin family TMF_DNA_bd PF12329.3 EMG50625.1 - 0.0043 16.8 11.5 0.0043 16.8 8.0 2.8 3 0 0 3 3 2 1 TATA element modulatory factor 1 DNA binding TMEM192 PF14802.1 EMG50625.1 - 0.017 14.0 1.2 0.017 14.0 0.9 1.8 2 0 0 2 2 2 0 TMEM192 family ADIP PF11559.3 EMG50625.1 - 0.028 14.3 7.3 0.028 14.3 5.0 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding MIP-T3 PF10243.4 EMG50625.1 - 0.082 11.3 43.5 0.1 11.0 30.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Reo_sigmaC PF04582.7 EMG50625.1 - 0.083 12.0 0.5 0.15 11.2 0.4 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein PilJ PF13675.1 EMG50625.1 - 0.091 13.0 2.0 0.11 12.8 0.1 2.0 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term MAGSP PF03082.9 EMG50625.1 - 0.32 10.3 8.9 0.055 12.8 0.5 2.1 2 0 0 2 2 2 0 Male accessory gland secretory protein Glyco_hydro_2_N PF02837.13 EMG50625.1 - 1.4 8.4 7.9 1.2 8.6 4.2 1.8 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, sugar binding domain FliD_N PF02465.13 EMG50625.1 - 2.8 8.3 13.6 0.053 13.8 1.5 2.6 3 0 0 3 3 2 0 Flagellar hook-associated protein 2 N-terminus Ribosomal_S8 PF00410.14 EMG50626.1 - 4.1e-15 55.7 0.0 5.6e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 PNK3P PF08645.6 EMG50628.1 - 1e-12 47.8 0.1 2.6e-12 46.4 0.0 1.6 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase Peptidase_M74 PF03411.8 EMG50628.1 - 0.079 12.1 0.0 0.083 12.0 0.0 1.3 1 1 0 1 1 1 0 Penicillin-insensitive murein endopeptidase Aminotran_1_2 PF00155.16 EMG50629.1 - 1.6e-05 24.0 0.0 2.1e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II MFS_1 PF07690.11 EMG50630.1 - 1.3e-33 116.1 39.6 5.5e-21 74.6 9.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMG50630.1 - 8.5e-06 24.6 44.7 1.1e-05 24.2 3.0 3.9 2 2 1 4 4 4 3 Sugar (and other) transporter Novirhabdo_Nv PF05554.6 EMG50630.1 - 0.012 15.1 0.1 0.024 14.1 0.1 1.5 1 0 0 1 1 1 0 Viral hemorrhagic septicemia virus non-virion protein MFS_1 PF07690.11 EMG50631.1 - 8.7e-33 113.4 8.7 8.7e-33 113.4 6.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMG50631.1 - 8.2e-06 24.2 0.3 1.3e-05 23.6 0.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pol_alpha_B_N PF08418.5 EMG50631.1 - 0.03 13.8 0.1 0.047 13.2 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Aminotran_1_2 PF00155.16 EMG50633.1 - 8.9e-05 21.5 0.0 0.00011 21.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Sec1 PF00995.18 EMG50634.1 - 1.7e-33 116.1 15.7 3.3e-33 115.1 10.9 1.5 1 1 0 1 1 1 1 Sec1 family ATP-synt_E_2 PF08112.6 EMG50634.1 - 0.0047 16.9 0.6 4.3 7.4 0.0 3.3 2 0 0 2 2 2 2 ATP synthase epsilon subunit 4HBT_3 PF13622.1 EMG50635.1 - 4.4e-24 85.6 0.0 5.6e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EMG50635.1 - 3.5e-09 36.3 0.1 5.7e-06 25.9 0.0 2.9 2 1 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.1 EMG50636.1 - 8.3e-26 91.2 0.0 3.8e-25 89.0 0.0 1.8 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EMG50636.1 - 3.5e-17 62.2 0.8 3.2e-12 46.2 0.4 2.9 2 1 0 2 2 2 2 Acyl-CoA thioesterase DUF1674 PF07896.7 EMG50637.1 - 2.3e-13 50.1 0.5 3.4e-13 49.5 0.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) DUF3597 PF12200.3 EMG50637.1 - 0.11 12.8 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) PI-PLC-X PF00388.14 EMG50638.1 - 8.8e-19 67.3 0.0 1.7e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Zip PF02535.17 EMG50639.1 - 1.1e-63 215.1 1.9 1.3e-63 214.9 1.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Cation_ATPase_C PF00689.16 EMG50639.1 - 4.3 6.8 9.4 10 5.6 0.3 3.2 2 2 0 2 2 2 0 Cation transporting ATPase, C-terminus Iso_dh PF00180.15 EMG50640.1 - 1.1e-71 241.6 0.0 1.2e-71 241.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-RING_5 PF14634.1 EMG50641.1 - 5.2e-10 38.8 4.7 8.8e-10 38.1 3.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EMG50641.1 - 0.0014 18.3 3.2 0.0024 17.6 2.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMG50641.1 - 0.002 17.7 1.7 0.0036 16.9 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Phage_GP20 PF06810.6 EMG50641.1 - 0.0026 17.2 2.6 0.0057 16.1 1.8 1.5 1 0 0 1 1 1 1 Phage minor structural protein GP20 Filament PF00038.16 EMG50641.1 - 0.0068 15.9 2.4 0.0078 15.7 0.6 1.7 2 0 0 2 2 2 1 Intermediate filament protein zf-C3HC4_2 PF13923.1 EMG50641.1 - 0.013 15.5 3.7 0.037 14.0 2.6 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4618 PF15397.1 EMG50641.1 - 0.027 13.8 3.3 0.042 13.1 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF603 PF04645.7 EMG50641.1 - 0.037 13.9 1.4 0.086 12.7 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF603 V-SNARE PF05008.10 EMG50641.1 - 0.058 13.5 1.6 0.93 9.6 0.1 2.7 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus ARS2 PF04959.8 EMG50641.1 - 0.07 13.3 0.6 0.15 12.2 0.2 1.7 1 1 0 1 1 1 0 Arsenite-resistance protein 2 BLOC1_2 PF10046.4 EMG50641.1 - 0.096 12.8 7.2 0.84 9.8 0.8 2.6 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PH_3 PF14593.1 EMG50641.1 - 0.1 12.5 0.5 20 5.1 0.3 3.0 2 1 1 3 3 3 0 PH domain zf-MIZ PF02891.15 EMG50641.1 - 0.1 12.1 5.2 0.83 9.2 3.6 2.3 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Rad50_zn_hook PF04423.9 EMG50641.1 - 0.11 12.0 1.1 3.3 7.2 0.0 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif SlyX PF04102.7 EMG50641.1 - 0.13 12.6 0.6 0.67 10.3 0.1 2.2 1 1 1 2 2 2 0 SlyX Laminin_II PF06009.7 EMG50641.1 - 0.17 11.6 3.0 0.14 11.8 0.2 2.1 2 0 0 2 2 2 0 Laminin Domain II Uds1 PF15456.1 EMG50641.1 - 0.2 11.6 0.2 0.2 11.6 0.1 2.1 2 1 0 2 2 2 0 Up-regulated During Septation TMF_DNA_bd PF12329.3 EMG50641.1 - 0.29 10.9 5.7 1.3 8.9 4.0 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Prok-RING_4 PF14447.1 EMG50641.1 - 0.32 10.5 2.3 15 5.2 0.0 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.20 EMG50641.1 - 0.9 9.2 4.7 1.8 8.2 3.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) COX7C PF02935.11 EMG50643.1 - 3.5e-14 52.3 1.6 4.5e-14 51.9 1.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc RFC1 PF08519.7 EMG50647.1 - 3.3e-53 179.6 1.8 3.3e-53 179.6 1.2 3.6 4 1 2 6 6 5 1 Replication factor RFC1 C terminal domain AAA PF00004.24 EMG50647.1 - 5.6e-11 42.7 0.6 3.4e-10 40.2 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.21 EMG50647.1 - 1.9e-09 37.5 5.0 5.5e-09 36.0 0.0 4.0 5 0 0 5 5 3 1 BRCA1 C Terminus (BRCT) domain AAA_17 PF13207.1 EMG50647.1 - 9.8e-06 26.3 0.0 0.00016 22.4 0.0 3.2 2 0 0 2 2 1 1 AAA domain GRAB PF10375.4 EMG50647.1 - 1.7e-05 24.2 1.1 4.6e-05 22.9 0.8 1.8 1 0 0 1 1 1 1 GRIP-related Arf-binding domain AAA_22 PF13401.1 EMG50647.1 - 0.00016 21.8 0.1 0.0019 18.3 0.0 3.0 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EMG50647.1 - 0.00067 19.6 0.0 0.00067 19.6 0.0 4.4 4 1 0 4 4 3 1 AAA ATPase domain Mnd1 PF03962.10 EMG50647.1 - 0.00081 19.0 15.4 0.00081 19.0 10.7 4.7 2 1 2 4 4 4 1 Mnd1 family RuvB_N PF05496.7 EMG50647.1 - 0.0012 17.9 0.0 0.0025 16.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Bacillus_HBL PF05791.6 EMG50647.1 - 0.0025 17.2 10.6 0.0025 17.2 7.3 4.3 3 1 1 4 4 3 2 Bacillus haemolytic enterotoxin (HBL) PTCB-BRCT PF12738.2 EMG50647.1 - 0.0041 16.9 0.0 0.018 14.9 0.0 2.2 1 0 0 1 1 1 1 twin BRCT domain AAA_19 PF13245.1 EMG50647.1 - 0.016 14.9 0.0 0.067 12.9 0.0 2.0 2 0 0 2 2 1 0 Part of AAA domain AAA_5 PF07728.9 EMG50647.1 - 0.018 14.7 3.3 0.96 9.1 0.0 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EMG50647.1 - 0.043 14.1 0.0 0.043 14.1 0.0 4.6 4 1 0 4 4 2 0 AAA domain ATG16 PF08614.6 EMG50647.1 - 0.091 12.5 66.0 2.2 8.0 8.4 4.8 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) FtsH_ext PF06480.10 EMG50647.1 - 0.57 10.3 7.6 0.31 11.2 0.7 3.3 2 0 0 2 2 2 0 FtsH Extracellular NPV_P10 PF05531.7 EMG50647.1 - 1.4 9.1 29.5 6.7 7.0 0.4 5.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EMG50647.1 - 4.1 6.9 72.3 0.19 11.3 10.6 5.1 2 1 3 5 5 5 0 IncA protein CALCOCO1 PF07888.6 EMG50647.1 - 5.3 5.2 52.3 0.16 10.2 31.6 1.7 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2722 PF10846.3 EMG50648.1 - 3.4e-105 352.4 62.0 9.7e-59 199.4 23.5 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2722) SHQ1 PF04925.10 EMG50650.1 - 1.8e-77 259.0 2.8 2.5e-77 258.6 1.9 1.2 1 0 0 1 1 1 1 SHQ1 protein Diphthamide_syn PF01866.12 EMG50651.1 - 3.6e-112 374.5 0.0 4.4e-112 374.2 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein COG6 PF06419.6 EMG50652.1 - 4.9e-141 470.9 28.2 2.9e-95 319.7 8.6 2.8 2 1 1 3 3 3 2 Conserved oligomeric complex COG6 NCD1 PF04904.8 EMG50652.1 - 0.015 15.0 0.4 1.8 8.3 0.0 3.1 3 0 0 3 3 3 0 NAB conserved region 1 (NCD1) T2SF PF00482.18 EMG50652.1 - 0.1 12.4 0.0 0.61 10.0 0.0 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF3355 PF11835.3 EMG50652.1 - 9.1 6.0 9.2 0.16 11.7 0.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3355) ADH_zinc_N_2 PF13602.1 EMG50653.1 - 4.1e-15 56.7 0.0 7.6e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EMG50653.1 - 2.2e-11 43.4 0.0 3.5e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMG50653.1 - 7.7e-07 28.8 0.0 1.2e-05 25.0 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain vATP-synt_E PF01991.13 EMG50653.1 - 0.034 13.4 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit THF_DHG_CYH_C PF02882.14 EMG50653.1 - 0.089 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Nop53 PF07767.6 EMG50654.1 - 2.9e-91 306.3 49.2 3.4e-91 306.1 34.1 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) bZIP_1 PF00170.16 EMG50654.1 - 0.093 12.6 17.7 0.24 11.4 11.2 2.6 2 0 0 2 2 2 0 bZIP transcription factor DUF4140 PF13600.1 EMG50654.1 - 0.97 9.9 11.5 0.33 11.4 2.5 2.9 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) MerR-DNA-bind PF09278.6 EMG50654.1 - 1 9.7 7.6 5 7.6 0.2 2.7 2 0 0 2 2 2 0 MerR, DNA binding Zn_clus PF00172.13 EMG50656.1 - 0.00016 21.5 8.9 0.00025 20.8 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EMG50657.1 - 5.8e-60 202.6 0.0 8.2e-60 202.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50657.1 - 3.1e-40 137.9 0.0 4.1e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG50657.1 - 2.2e-07 30.1 0.0 4.2e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EMG50657.1 - 0.0005 18.9 0.0 0.00081 18.3 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 EMG50657.1 - 0.0046 16.0 0.0 0.0095 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EMG50657.1 - 0.017 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 EMG50657.1 - 0.034 13.8 0.0 0.091 12.4 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Epimerase PF01370.16 EMG50658.1 - 7.5e-21 74.6 0.1 1.3e-20 73.9 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMG50658.1 - 6.5e-18 64.4 0.1 1.1e-17 63.6 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMG50658.1 - 1.1e-15 58.0 0.1 1.7e-15 57.4 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMG50658.1 - 5.4e-14 51.7 0.0 9.7e-13 47.6 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EMG50658.1 - 1.8e-07 31.2 0.0 4.5e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EMG50658.1 - 5.4e-06 25.8 1.2 5.7e-05 22.4 0.3 2.3 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 EMG50658.1 - 2.3e-05 24.1 0.0 4.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EMG50658.1 - 5.1e-05 22.3 0.6 8.9e-05 21.5 0.4 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DapB_N PF01113.15 EMG50658.1 - 0.0035 17.2 0.1 0.0081 16.0 0.1 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.12 EMG50658.1 - 0.0038 16.1 0.0 0.0081 15.0 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain Sigma54_activ_2 PF14532.1 EMG50658.1 - 0.009 16.0 0.0 0.051 13.6 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain Semialdhyde_dh PF01118.19 EMG50658.1 - 0.054 13.7 0.1 0.39 11.0 0.0 2.2 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF867 PF05908.6 EMG50658.1 - 0.069 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF867) Abhydrolase_1 PF00561.15 EMG50658.1 - 0.073 12.6 0.0 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold COG4 PF08318.7 EMG50659.1 - 4.6e-114 380.6 6.8 4.6e-114 380.6 4.7 3.0 3 0 0 3 3 3 2 COG4 transport protein zf-CCCH PF00642.19 EMG50660.1 - 1.3e-14 53.4 31.4 0.00011 21.7 0.9 5.8 6 0 0 6 6 6 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EMG50660.1 - 0.061 13.3 39.8 0.33 11.0 0.7 6.8 5 2 1 7 7 7 0 Zinc finger C-x8-C-x5-C-x3-H type FAD_binding_2 PF00890.19 EMG50661.1 - 1e-73 248.5 0.0 1.2e-73 248.3 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMG50661.1 - 5.5e-10 38.6 0.0 3.4e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMG50661.1 - 2.5e-09 37.0 0.0 1.8e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMG50661.1 - 7e-09 35.8 0.6 0.00029 20.7 0.0 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMG50661.1 - 2.5e-08 32.8 0.9 0.00082 17.9 0.0 3.9 4 0 0 4 4 4 3 HI0933-like protein Thi4 PF01946.12 EMG50661.1 - 6.8e-08 31.8 0.8 0.0083 15.2 0.1 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox_3 PF13738.1 EMG50661.1 - 1.9e-05 24.8 0.0 0.00042 20.4 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMG50661.1 - 0.00011 21.4 0.0 0.00026 20.1 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EMG50661.1 - 0.00043 19.2 0.0 0.0064 15.4 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EMG50661.1 - 0.01 14.9 0.1 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EMG50661.1 - 0.042 12.7 0.0 1 8.1 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein GMC_oxred_N PF00732.14 EMG50661.1 - 0.086 11.9 0.0 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase NAD_binding_9 PF13454.1 EMG50661.1 - 0.15 11.8 0.1 3.5 7.4 0.1 2.6 1 1 0 1 1 1 0 FAD-NAD(P)-binding Ribosomal_L35Ae PF01247.13 EMG50662.1 - 2.7e-40 136.0 0.8 3e-40 135.8 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EMG50662.1 - 0.02 14.7 0.0 5.9 6.8 0.0 2.2 2 0 0 2 2 2 0 RimM N-terminal domain Oxysterol_BP PF01237.13 EMG50663.1 - 2.6e-93 312.3 3.0 3.1e-93 312.1 2.1 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Kinesin-relat_1 PF12711.2 EMG50663.1 - 0.041 14.2 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 Kinesin motor GWT1 PF06423.7 EMG50664.1 - 1.7e-40 138.2 9.3 1.7e-40 138.2 6.4 2.4 2 0 0 2 2 2 1 GWT1 UPF0233 PF06781.7 EMG50664.1 - 0.66 9.6 5.4 3.3 7.4 0.0 3.7 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0233) Spo7 PF03907.8 EMG50665.1 - 2e-78 262.7 5.6 3.3e-78 262.0 3.9 1.3 1 0 0 1 1 1 1 Spo7-like protein rve PF00665.21 EMG50665.1 - 8.4e-07 29.1 0.1 2.6e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain ADH_zinc_N_2 PF13602.1 EMG50666.1 - 1e-16 62.0 0.0 1.7e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EMG50666.1 - 1.6e-12 47.0 0.0 2.6e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMG50666.1 - 4.6e-07 29.5 0.0 4.9e-06 26.2 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain THF_DHG_CYH_C PF02882.14 EMG50666.1 - 0.081 12.0 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CTP_transf_3 PF02348.14 EMG50666.1 - 0.088 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase vATP-synt_E PF01991.13 EMG50666.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit zf-CSL PF05207.8 EMG50667.1 - 4.1e-24 83.8 1.5 5.1e-24 83.5 1.1 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 EMG50667.1 - 0.096 12.6 1.4 0.18 11.8 1.0 1.5 1 1 0 1 1 1 0 Zinc ribbon domain Ribosomal_S8e PF01201.17 EMG50668.1 - 1.8e-50 170.4 1.7 2.1e-50 170.2 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e GATase PF00117.23 EMG50669.1 - 3.6e-06 26.5 0.3 1e-05 25.0 0.2 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EMG50669.1 - 0.12 11.7 0.2 0.35 10.2 0.1 1.7 1 1 0 1 1 1 0 Peptidase C26 Myb_DNA-binding PF00249.26 EMG50671.1 - 8.9e-27 92.9 2.5 5.2e-14 52.0 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMG50671.1 - 3.6e-18 65.4 1.7 4.6e-13 49.0 0.1 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain TMPIT PF07851.8 EMG50671.1 - 5.4 5.9 11.8 10 5.0 8.2 1.4 1 0 0 1 1 1 0 TMPIT-like protein DUF3043 PF11241.3 EMG50671.1 - 8 6.0 7.0 15 5.1 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) ADH_N PF08240.7 EMG50672.1 - 3.9e-06 26.5 0.0 1.4e-05 24.7 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain PNGaseA PF12222.3 EMG50673.1 - 3.7e-57 194.1 2.1 2.2e-29 102.5 0.4 2.2 2 0 0 2 2 2 2 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Vps35 PF03635.12 EMG50674.1 - 2e-246 819.8 34.6 2.3e-246 819.6 24.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 ADH_zinc_N_2 PF13602.1 EMG50675.1 - 1.6e-16 61.3 0.0 2.6e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EMG50675.1 - 6.6e-13 48.3 0.0 9.5e-13 47.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CTP_transf_3 PF02348.14 EMG50675.1 - 0.041 13.4 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase vATP-synt_E PF01991.13 EMG50675.1 - 0.086 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit THF_DHG_CYH_C PF02882.14 EMG50675.1 - 0.099 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 EMG50675.1 - 0.14 11.5 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMG50675.1 - 0.14 12.0 0.0 0.34 10.8 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase Epimerase PF01370.16 EMG50676.1 - 7.5e-20 71.3 0.2 2e-19 69.9 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMG50676.1 - 6.9e-17 61.0 0.0 9.5e-17 60.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMG50676.1 - 8.1e-16 58.5 0.1 1.3e-15 57.9 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMG50676.1 - 1e-12 47.5 0.0 3.6e-11 42.4 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EMG50676.1 - 7.8e-07 28.5 1.2 3.3e-05 23.2 0.2 2.3 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EMG50676.1 - 8.7e-07 29.0 0.0 2.5e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMG50676.1 - 0.00011 21.8 0.0 0.00026 20.7 0.0 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EMG50676.1 - 0.00013 20.9 0.2 0.00023 20.1 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DapB_N PF01113.15 EMG50676.1 - 0.011 15.7 0.1 0.024 14.5 0.0 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sigma54_activ_2 PF14532.1 EMG50676.1 - 0.016 15.2 0.0 0.072 13.1 0.0 2.0 1 1 1 2 2 2 0 Sigma-54 interaction domain RmlD_sub_bind PF04321.12 EMG50676.1 - 0.039 12.8 0.0 0.079 11.8 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain Abhydrolase_1 PF00561.15 EMG50676.1 - 0.061 12.8 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF867 PF05908.6 EMG50676.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF867) ADH_zinc_N PF00107.21 EMG50677.1 - 5.8e-13 48.5 0.0 9.4e-13 47.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMG50677.1 - 8.2e-07 28.7 0.0 1.4e-05 24.7 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain vATP-synt_E PF01991.13 EMG50677.1 - 0.028 13.6 0.0 0.041 13.1 0.0 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit THF_DHG_CYH_C PF02882.14 EMG50677.1 - 0.1 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain tRNA_int_endo PF01974.12 EMG50678.1 - 8.3e-08 31.9 0.9 1.3e-07 31.2 0.6 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain AATase PF07247.7 EMG50679.1 - 7.3e-45 153.4 2.5 7.3e-45 153.4 1.7 2.2 3 0 0 3 3 3 1 Alcohol acetyltransferase Ran_BP1 PF00638.13 EMG50680.1 - 1.2e-23 83.4 0.1 2.1e-23 82.6 0.1 1.4 1 0 0 1 1 1 1 RanBP1 domain Herpes_UL6 PF01763.11 EMG50680.1 - 0.046 11.9 0.1 0.075 11.1 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like U1snRNP70_N PF12220.3 EMG50681.1 - 6.7e-17 61.6 7.3 1.9e-16 60.1 5.1 1.8 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EMG50681.1 - 1.4e-15 56.6 0.0 2.5e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG50681.1 - 2.6e-12 46.5 0.0 4.3e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG50681.1 - 4.9e-08 32.6 0.0 8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lipoprotein_7 PF01540.11 EMG50681.1 - 0.0096 15.0 0.5 0.014 14.5 0.4 1.1 1 0 0 1 1 1 1 Adhesin lipoprotein Cyt-b5 PF00173.23 EMG50682.1 - 1e-10 41.2 0.1 1.3e-10 40.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AA_permease PF00324.16 EMG50683.1 - 1.7e-90 303.6 40.0 2.3e-90 303.2 27.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMG50683.1 - 3.1e-22 78.7 44.5 4.4e-22 78.2 30.9 1.2 1 0 0 1 1 1 1 Amino acid permease Homeobox PF00046.24 EMG50683.1 - 0.26 10.9 1.4 2.8 7.6 0.1 2.4 2 0 0 2 2 2 0 Homeobox domain Nucleos_tra2_C PF07662.8 EMG50684.1 - 8.9e-65 218.0 2.2 8.9e-65 218.0 1.5 2.5 2 2 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EMG50684.1 - 2.8e-21 75.6 2.0 2.8e-21 75.6 1.4 4.0 4 1 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus DUF912 PF06024.7 EMG50684.1 - 0.041 13.9 0.1 0.041 13.9 0.1 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ATG2_CAD PF13329.1 EMG50685.1 - 2.5e-47 160.3 0.6 1.5e-46 157.8 0.0 2.8 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 EMG50685.1 - 6.2e-24 83.9 0.0 1.9e-23 82.4 0.0 1.9 1 0 0 1 1 1 1 ATG C terminal domain Las1 PF04031.8 EMG50686.1 - 9e-53 178.0 0.2 6e-52 175.4 0.1 2.1 2 0 0 2 2 2 1 Las1-like 4HBT_3 PF13622.1 EMG50687.1 - 1.8e-37 129.4 0.0 2.4e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EMG50687.1 - 3.5e-10 39.6 4.0 7.6e-05 22.3 0.8 3.9 2 2 1 3 3 3 3 Acyl-CoA thioesterase DUF4230 PF14014.1 EMG50687.1 - 0.053 13.3 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) 4HBT_3 PF13622.1 EMG50688.1 - 1.2e-20 74.3 0.0 1.6e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EMG50688.1 - 1.8e-12 47.0 0.7 2.4e-10 40.1 0.2 2.8 2 1 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.1 EMG50689.1 - 1.6e-27 96.8 0.0 2.1e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EMG50689.1 - 8.8e-19 67.4 1.6 8.8e-11 41.5 0.4 3.2 2 1 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.1 EMG50690.1 - 3.7e-31 108.7 0.0 4.3e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EMG50690.1 - 2.3e-14 53.1 0.1 3.7e-11 42.7 0.1 2.9 2 1 0 2 2 2 2 Acyl-CoA thioesterase Methyltransf_31 PF13847.1 EMG50691.1 - 1.4e-20 73.3 0.1 2.7e-20 72.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMG50691.1 - 4.8e-12 46.4 0.0 8.5e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMG50691.1 - 5.1e-08 33.2 0.7 1.2e-07 32.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMG50691.1 - 1.5e-07 31.7 0.1 3.8e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMG50691.1 - 1.8e-06 28.3 0.0 3.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMG50691.1 - 2.8e-05 24.1 0.0 4.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EMG50691.1 - 4.4e-05 23.1 0.0 5.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMG50691.1 - 0.0018 17.4 0.0 0.0024 17.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF748 PF05359.6 EMG50691.1 - 0.0036 17.3 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF748) Methyltransf_23 PF13489.1 EMG50691.1 - 0.0036 17.0 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 EMG50691.1 - 0.02 14.2 0.0 0.04 13.3 0.0 1.4 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 EMG50691.1 - 0.091 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain RVT_1 PF00078.22 EMG50692.1 - 2.2e-27 95.8 0.5 7.8e-27 94.0 0.3 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 EMG50692.1 - 5e-05 23.3 0.0 9.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RdRP_1 PF00680.15 EMG50692.1 - 0.00023 19.5 0.3 0.00054 18.3 0.0 1.7 2 0 0 2 2 2 1 RNA dependent RNA polymerase HEXIM PF15313.1 EMG50692.1 - 0.67 10.1 4.8 5.7 7.1 0.2 3.0 3 0 0 3 3 3 0 Hexamethylene bis-acetamide-inducible protein Aminotran_5 PF00266.14 EMG50693.1 - 2e-38 132.1 0.0 2.4e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V DHHA2 PF02833.9 EMG50694.1 - 8.9e-27 93.8 0.6 1.9e-26 92.7 0.4 1.6 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EMG50694.1 - 5.3e-12 45.6 0.2 1e-11 44.7 0.1 1.4 1 0 0 1 1 1 1 DHH family DUF1959 PF09218.5 EMG50694.1 - 0.00072 19.3 0.2 3.5 7.4 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF1959) PMT PF02366.13 EMG50695.1 - 1e-79 267.3 24.2 2e-79 266.4 16.8 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EMG50695.1 - 3.5e-21 75.6 0.9 7e-21 74.6 0.6 1.5 1 0 0 1 1 1 1 MIR domain Hamartin PF04388.7 EMG50696.1 - 1.8e-19 69.9 2.1 1.8e-19 69.9 1.5 2.0 2 1 1 3 3 3 1 Hamartin protein DUF3556 PF12077.3 EMG50696.1 - 0.29 9.0 0.0 0.43 8.5 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein of unknown function (DUF3556) FlxA PF14282.1 EMG50696.1 - 5.8 6.9 19.2 10 6.1 3.0 3.4 1 1 1 2 2 2 0 FlxA-like protein NUDIX PF00293.23 EMG50697.1 - 1e-05 25.1 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain AMP-binding PF00501.23 EMG50698.1 - 6.5e-66 222.4 0.0 8.9e-66 221.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Mre11_DNA_bind PF04152.9 EMG50698.1 - 0.044 13.6 0.1 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 Mre11 DNA-binding presumed domain rpo132 PF12415.3 EMG50699.1 - 0.13 11.2 1.1 0.36 9.8 0.5 1.9 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase GTP_EFTU PF00009.22 EMG50700.1 - 3.9e-48 163.3 0.0 6.7e-48 162.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EMG50700.1 - 1.7e-35 121.1 3.7 3.4e-35 120.2 2.6 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EMG50700.1 - 1.1e-21 76.4 0.0 2.6e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EMG50700.1 - 1e-05 25.5 0.4 6.3e-05 23.0 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Ras PF00071.17 EMG50700.1 - 0.00054 19.3 0.0 0.00096 18.5 0.0 1.4 1 0 0 1 1 1 1 Ras family EFG_II PF14492.1 EMG50700.1 - 0.0035 17.1 0.0 0.009 15.8 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 EMG50700.1 - 0.0061 15.7 0.0 0.015 14.5 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EMG50700.1 - 0.034 14.6 0.0 0.076 13.5 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein PALP PF00291.20 EMG50701.1 - 7.8e-73 245.3 0.0 1.1e-72 244.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EMG50701.1 - 1.7e-18 65.9 0.0 3.2e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 C-terminal regulatory domain of Threonine dehydratase UPF0180 PF03698.8 EMG50701.1 - 0.092 12.5 0.0 0.65 9.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) NIR_SIR PF01077.17 EMG50703.1 - 9.3e-51 171.2 0.0 1.4e-45 154.4 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EMG50703.1 - 4.1e-30 103.2 0.0 1.5e-14 53.3 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EMG50703.1 - 9.3e-28 97.0 0.1 2.9e-27 95.4 0.1 1.9 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 EMG50703.1 - 1.9e-07 30.8 0.0 6.7e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg VWA_2 PF13519.1 EMG50704.1 - 1.7e-11 44.5 0.0 2.4e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ku_N PF03731.10 EMG50704.1 - 9.2e-07 28.5 0.2 0.0011 18.4 0.2 2.3 1 1 1 2 2 2 2 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.23 EMG50704.1 - 1.3e-05 24.9 0.7 2.1e-05 24.3 0.5 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EMG50704.1 - 2.5e-05 23.9 0.0 3.4e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 EMG50704.1 - 0.016 14.6 1.0 0.053 13.1 0.7 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif PDH PF02153.12 EMG50704.1 - 0.018 13.9 0.0 0.03 13.2 0.0 1.4 1 0 0 1 1 1 0 Prephenate dehydrogenase Prp18 PF02840.10 EMG50704.1 - 0.69 9.7 3.3 0.24 11.2 0.2 1.7 2 0 0 2 2 2 0 Prp18 domain GAF_3 PF13492.1 EMG50705.1 - 2.9e-05 24.1 0.0 6.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 EMG50705.1 - 0.00016 21.8 0.0 0.00028 21.0 0.0 1.4 1 0 0 1 1 1 1 GAF domain Swi3 PF07962.7 EMG50706.1 - 7.8e-31 105.5 0.1 1.3e-30 104.8 0.1 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 HECT_2 PF09814.4 EMG50707.1 - 1.6e-39 135.6 0.2 1.9e-39 135.3 0.1 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Hyphal_reg_CWP PF11765.3 EMG50709.1 - 7.7e-42 143.2 10.6 1.3e-41 142.4 7.3 1.3 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal DUF4176 PF13780.1 EMG50709.1 - 0.054 13.2 0.4 25 4.6 0.0 3.7 2 1 2 4 4 4 0 Domain of unknown function (DUF4176) Hus1 PF04005.7 EMG50710.1 - 3.8e-67 226.3 1.4 4.3e-67 226.1 1.0 1.0 1 0 0 1 1 1 1 Hus1-like protein CPSF73-100_C PF11718.3 EMG50711.1 - 4.7e-77 258.1 2.0 8.3e-77 257.3 1.4 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EMG50711.1 - 1.5e-33 115.4 0.1 1.5e-32 112.2 0.0 2.4 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 EMG50711.1 - 1.4e-15 57.5 1.1 2.8e-15 56.4 0.2 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMG50711.1 - 1.1e-12 47.8 0.3 2.7e-12 46.6 0.2 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EMG50711.1 - 1.5e-07 31.1 1.1 3.7e-07 29.8 0.1 2.2 2 0 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EMG50711.1 - 5.6e-07 29.4 0.5 1.3e-05 24.9 0.0 2.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain VirionAssem_T7 PF11653.3 EMG50711.1 - 0.033 14.9 0.4 0.46 11.2 0.3 2.3 2 0 0 2 2 2 0 Bacteriophage T7 virion assembly protein DUF2457 PF10446.4 EMG50711.1 - 1.3 7.7 9.1 1.9 7.1 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RTA1 PF04479.8 EMG50712.1 - 5.8e-58 196.0 9.0 1.5e-57 194.6 6.3 1.6 1 1 0 1 1 1 1 RTA1 like protein RTA1 PF04479.8 EMG50713.1 - 1.7e-56 191.2 12.0 5.5e-56 189.5 8.3 1.8 1 1 0 1 1 1 1 RTA1 like protein S-antigen PF05756.6 EMG50713.1 - 0.11 12.4 1.0 0.36 10.8 0.7 1.9 1 0 0 1 1 1 0 S-antigen protein Glyoxalase_2 PF12681.2 EMG50714.1 - 8.7e-10 39.1 0.0 1.4e-09 38.4 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EMG50714.1 - 3.6e-09 36.6 0.0 1.5e-08 34.6 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EMG50714.1 - 9e-06 25.6 0.0 1.4e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EMG50714.1 - 0.016 15.1 0.0 0.055 13.3 0.0 1.9 1 1 0 1 1 1 0 Glyoxalase-like domain ADIP PF11559.3 EMG50715.1 - 5.9e-29 100.9 21.7 7.5e-29 100.5 15.1 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 EMG50715.1 - 0.00069 18.8 2.4 0.00093 18.4 1.6 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Rabaptin PF03528.10 EMG50715.1 - 0.0046 16.8 5.2 0.0096 15.8 3.6 1.6 1 0 0 1 1 1 1 Rabaptin FlxA PF14282.1 EMG50715.1 - 0.0057 16.5 18.6 0.02 14.8 2.2 2.8 2 1 1 3 3 2 2 FlxA-like protein Ax_dynein_light PF10211.4 EMG50715.1 - 0.0076 16.1 6.8 0.0076 16.1 4.7 2.3 2 0 0 2 2 2 1 Axonemal dynein light chain DUF641 PF04859.7 EMG50715.1 - 0.0094 15.7 9.6 0.082 12.6 2.4 2.4 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) CENP-F_leu_zip PF10473.4 EMG50715.1 - 0.048 13.5 9.3 0.099 12.5 6.4 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 EMG50715.1 - 0.054 11.2 14.8 0.11 10.2 10.4 1.4 1 1 0 1 1 1 0 Myosin tail Colicin PF01024.14 EMG50715.1 - 0.092 12.3 6.4 0.16 11.5 4.5 1.4 1 0 0 1 1 1 0 Colicin pore forming domain Mto2_bdg PF12808.2 EMG50715.1 - 0.1 12.7 1.2 0.54 10.4 0.5 2.5 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region FemAB PF02388.11 EMG50715.1 - 0.1 11.2 6.8 0.15 10.7 4.7 1.3 1 0 0 1 1 1 0 FemAB family SlyX PF04102.7 EMG50715.1 - 0.14 12.5 4.9 0.48 10.8 0.5 3.2 2 1 1 3 3 3 0 SlyX IncA PF04156.9 EMG50715.1 - 0.24 11.0 7.7 0.63 9.6 5.4 1.8 1 1 0 1 1 1 0 IncA protein Nup54 PF13874.1 EMG50715.1 - 0.24 11.0 11.8 1.8 8.2 3.0 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF3573 PF12097.3 EMG50715.1 - 0.36 9.3 15.8 0.2 10.2 9.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) DUF4200 PF13863.1 EMG50715.1 - 0.46 10.4 16.1 0.78 9.7 10.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) LMBR1 PF04791.11 EMG50715.1 - 0.62 8.5 4.5 0.76 8.2 3.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein FlaC_arch PF05377.6 EMG50715.1 - 0.76 9.7 7.3 12 5.9 1.3 3.0 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF2524 PF10732.4 EMG50715.1 - 0.97 9.6 6.2 2 8.5 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2524) DUF2802 PF10975.3 EMG50715.1 - 1.1 9.0 4.1 19 5.1 0.4 2.9 2 1 1 3 3 2 0 Protein of unknown function (DUF2802) IFT20 PF14931.1 EMG50715.1 - 1.1 9.1 14.2 0.4 10.5 4.3 2.4 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF2779 PF11074.3 EMG50715.1 - 1.5 8.8 5.3 4.1 7.4 3.6 1.8 1 1 0 1 1 1 0 Domain of unknown function(DUF2779) TMF_DNA_bd PF12329.3 EMG50715.1 - 2.4 8.0 19.3 0.29 10.9 4.1 3.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding AKNA PF12443.3 EMG50715.1 - 2.6 8.1 7.8 0.89 9.6 2.3 2.3 1 1 1 2 2 2 0 AT-hook-containing transcription factor Remorin_C PF03763.8 EMG50715.1 - 2.8 7.5 12.1 0.38 10.2 4.8 2.0 1 1 1 2 2 2 0 Remorin, C-terminal region TPR_MLP1_2 PF07926.7 EMG50715.1 - 5.7 6.6 18.1 0.83 9.4 3.1 2.8 2 1 1 3 3 2 0 TPR/MLP1/MLP2-like protein Sec2p PF06428.6 EMG50715.1 - 7.6 6.4 13.8 11 5.9 5.5 3.1 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p RF-1 PF00472.15 EMG50716.1 - 7.4e-23 80.5 2.4 7.4e-23 80.5 1.6 1.8 1 1 1 2 2 2 1 RF-1 domain DUF2422 PF10337.4 EMG50716.1 - 0.061 12.1 0.7 0.092 11.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) MCM PF00493.18 EMG50717.1 - 1.8e-141 470.7 0.1 2.6e-141 470.2 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EMG50717.1 - 5.5e-22 78.5 1.2 5.5e-22 78.5 0.8 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EMG50717.1 - 1.3e-06 27.7 0.0 0.00077 18.6 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EMG50717.1 - 2.2e-05 24.1 0.0 6e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EMG50717.1 - 0.00027 20.5 0.1 0.0022 17.5 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 EMG50717.1 - 0.034 14.5 0.4 0.15 12.4 0.3 2.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EMG50717.1 - 0.052 13.0 0.0 1.9 7.9 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Imm19 PF15567.1 EMG50717.1 - 0.15 12.1 0.0 0.44 10.5 0.0 1.8 1 0 0 1 1 1 0 Immunity protein 19 KilA-N PF04383.8 EMG50719.1 - 0.00028 20.4 0.1 0.00028 20.4 0.1 3.5 2 2 0 2 2 2 1 KilA-N domain Glyoxalase PF00903.20 EMG50720.1 - 1.9e-08 34.3 0.1 6.6e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EMG50720.1 - 5.6e-06 26.3 0.0 0.0011 18.9 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Tn7_Tnp_TnsA_C PF08721.6 EMG50720.1 - 0.00044 20.2 1.9 0.091 12.7 0.1 2.6 2 0 0 2 2 2 2 TnsA endonuclease C terminal Glyoxalase_3 PF13468.1 EMG50720.1 - 0.088 12.7 0.0 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 Glyoxalase-like domain RTA1 PF04479.8 EMG50721.1 - 3.3e-51 173.9 12.4 7.9e-51 172.7 8.6 1.6 1 1 0 1 1 1 1 RTA1 like protein Pox_D5 PF03288.11 EMG50721.1 - 0.056 13.7 0.4 0.11 12.7 0.3 1.4 1 0 0 1 1 1 0 Poxvirus D5 protein-like DUF3754 PF12576.3 EMG50721.1 - 0.44 10.1 3.9 0.41 10.2 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3754) zf-DHHC PF01529.15 EMG50721.1 - 1.6 8.1 12.2 0.11 11.8 0.5 2.8 2 1 0 2 2 2 0 DHHC palmitoyltransferase RTA1 PF04479.8 EMG50722.1 - 2.7e-56 190.5 16.0 5.5e-56 189.5 11.1 1.5 1 1 0 1 1 1 1 RTA1 like protein WHIM2 PF15613.1 EMG50722.1 - 0.79 9.7 5.3 10 6.2 0.3 4.0 4 0 0 4 4 4 0 WSTF, HB1, Itc1p, MBD9 motif 2 RRM_6 PF14259.1 EMG50723.1 - 8.8e-12 44.8 1.3 3.1e-07 30.2 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 EMG50723.1 - 1.7e-10 40.2 12.4 1.7e-10 40.2 8.6 3.6 3 0 0 3 3 3 1 Putative RRM domain RRM_1 PF00076.17 EMG50723.1 - 1.9e-09 37.0 2.8 0.0061 16.1 0.0 4.5 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG50723.1 - 0.00016 21.4 1.1 1 9.2 0.1 4.3 4 1 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aa_trans PF01490.13 EMG50724.1 - 8.2e-53 179.3 31.7 1e-52 179.0 22.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein B56 PF01603.15 EMG50725.1 - 2.3e-150 500.7 17.6 6.8e-144 479.4 8.3 2.4 3 0 0 3 3 3 2 Protein phosphatase 2A regulatory B subunit (B56 family) IMPDH PF00478.20 EMG50726.1 - 4.5e-142 473.1 2.2 5.2e-142 472.9 1.5 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EMG50726.1 - 2.3e-13 49.7 0.1 5e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 EMG50726.1 - 1.6e-08 33.8 1.1 7.5e-08 31.6 0.9 2.0 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 EMG50726.1 - 2e-08 33.7 6.4 7.6e-05 22.0 3.5 2.5 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.16 EMG50726.1 - 4.5e-05 22.8 1.2 0.00078 18.7 0.8 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 EMG50726.1 - 0.0014 17.7 2.0 0.003 16.6 0.3 2.0 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG EAL PF00563.15 EMG50726.1 - 0.0031 17.0 0.1 0.047 13.1 0.0 2.1 2 0 0 2 2 2 1 EAL domain Aldolase PF01081.14 EMG50726.1 - 0.0083 15.3 0.1 0.026 13.6 0.0 1.8 1 0 0 1 1 1 1 KDPG and KHG aldolase DUF1273 PF06908.6 EMG50726.1 - 0.035 13.7 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) B12-binding PF02310.14 EMG50726.1 - 0.088 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain Ribosomal_L28e PF01778.12 EMG50727.1 - 1.6e-31 109.1 4.4 1.6e-31 109.1 3.0 2.2 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 EMG50727.1 - 2.6e-29 101.2 25.9 2.6e-29 101.2 17.9 2.5 1 1 1 2 2 2 1 Mak16 protein C-terminal region CH PF00307.26 EMG50727.1 - 9.6e-06 25.6 0.1 2.5e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain BUD22 PF09073.5 EMG50727.1 - 0.00031 19.9 24.0 0.00048 19.3 16.7 1.3 1 0 0 1 1 1 1 BUD22 TFIIF_alpha PF05793.7 EMG50727.1 - 0.0033 15.8 27.0 0.0049 15.3 18.7 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Na_trans_assoc PF06512.8 EMG50727.1 - 0.016 15.1 20.2 0.03 14.3 14.0 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.7 EMG50727.1 - 0.82 7.5 40.2 1.2 6.9 27.9 1.2 1 0 0 1 1 1 0 Nop14-like family ATP_sub_h PF10775.4 EMG50728.1 - 5.1e-24 83.7 0.6 6.8e-24 83.3 0.4 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h zf-U1 PF06220.7 EMG50729.1 - 3.9e-18 64.6 10.9 8.9e-18 63.5 7.5 1.6 1 1 0 1 1 1 1 U1 zinc finger PyrI_C PF02748.10 EMG50729.1 - 3.1 7.3 7.3 12 5.3 0.1 2.4 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Ras PF00071.17 EMG50730.1 - 4.6e-49 165.9 0.0 5.7e-49 165.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMG50730.1 - 8.6e-15 55.2 0.0 1.8e-14 54.2 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMG50730.1 - 1.5e-10 40.5 0.0 1.9e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EMG50730.1 - 0.00038 20.5 0.1 0.0018 18.4 0.0 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 EMG50730.1 - 0.00075 18.7 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 EMG50730.1 - 0.028 13.7 0.1 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.15 EMG50730.1 - 0.058 12.0 2.4 1.1 7.8 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit AAA_22 PF13401.1 EMG50730.1 - 0.061 13.4 0.2 0.19 11.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EMG50730.1 - 0.08 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EMG50730.1 - 0.08 12.0 0.2 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 KaiC Pkinase PF00069.20 EMG50732.1 - 1.3e-37 129.3 0.4 2.9e-18 65.9 0.0 3.9 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50732.1 - 1.9e-12 46.8 0.1 0.0033 16.5 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase Kdo PF06293.9 EMG50732.1 - 0.014 14.4 0.0 0.03 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMG50732.1 - 0.026 13.5 0.1 0.14 11.0 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Tbf5 PF06331.7 EMG50732.1 - 0.21 11.4 4.3 0.29 10.9 1.4 2.2 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 Epimerase PF01370.16 EMG50733.1 - 1.8e-15 57.0 0.0 2.5e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMG50733.1 - 7.9e-14 51.0 0.0 1.1e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMG50733.1 - 1.4e-08 33.9 0.0 4.7e-08 32.2 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EMG50733.1 - 2.2e-08 34.3 0.7 6.8e-08 32.7 0.5 1.8 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMG50733.1 - 2.6e-06 27.4 0.0 4.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EMG50733.1 - 9.5e-06 24.7 0.0 1.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EMG50733.1 - 4.2e-05 23.2 0.0 7.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 EMG50733.1 - 0.0018 18.6 0.0 0.004 17.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF3502 PF12010.3 EMG50733.1 - 0.013 15.5 0.3 0.16 11.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3502) NmrA PF05368.8 EMG50733.1 - 0.024 13.9 0.6 0.038 13.2 0.2 1.6 2 1 0 2 2 2 0 NmrA-like family RmlD_sub_bind PF04321.12 EMG50733.1 - 0.079 11.8 0.0 0.46 9.3 0.0 2.1 2 1 0 2 2 2 0 RmlD substrate binding domain Mpv17_PMP22 PF04117.7 EMG50734.1 - 1.4e-21 75.9 5.6 2.9e-21 74.8 3.9 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.7 EMG50735.1 - 2e-25 88.2 7.4 1.1e-24 85.7 3.3 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family RRN9 PF10680.4 EMG50735.1 - 0.22 11.2 2.4 11 5.8 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor BACK PF07707.10 EMG50736.1 - 0.16 11.7 0.7 0.49 10.2 0.2 1.9 2 0 0 2 2 2 0 BTB And C-terminal Kelch HAD PF12710.2 EMG50739.1 - 7.2e-23 81.7 0.1 1.3e-22 80.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMG50739.1 - 1e-22 81.6 0.0 4.9e-22 79.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EMG50739.1 - 9.3e-21 73.9 0.1 2.4e-20 72.5 0.0 1.7 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EMG50739.1 - 1.6e-06 28.0 0.0 6.6e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMG50739.1 - 9.9e-06 25.3 0.3 2.4e-05 24.0 0.2 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EMG50739.1 - 0.04 13.2 0.0 0.13 11.4 0.0 1.7 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Sugar_tr PF00083.19 EMG50740.1 - 1e-49 169.4 30.4 3.5e-49 167.5 21.1 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG50740.1 - 3.6e-20 71.9 53.5 4.5e-14 51.9 23.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMG50740.1 - 0.00099 17.6 20.3 0.31 9.3 0.0 3.3 3 1 0 3 3 3 3 MFS/sugar transport protein BT1 PF03092.11 EMG50740.1 - 0.0013 17.5 1.0 0.051 12.2 0.0 2.3 2 0 0 2 2 2 2 BT1 family DUF606 PF04657.8 EMG50740.1 - 0.0017 18.4 2.0 0.0017 18.4 1.4 3.8 2 2 1 3 3 3 2 Protein of unknown function, DUF606 Pkinase PF00069.20 EMG50741.1 - 1.1e-52 178.7 2.0 3.4e-52 177.1 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50741.1 - 2.4e-27 95.6 0.0 3.1e-19 69.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EMG50741.1 - 2.8e-06 27.7 1.0 1.7e-05 25.2 0.7 2.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMG50741.1 - 1.2e-05 24.4 0.0 0.0043 16.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EMG50741.1 - 0.008 15.2 0.0 0.017 14.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMG50741.1 - 0.013 15.2 0.0 0.056 13.1 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Prp31_C PF09785.4 EMG50742.1 - 5.3e-35 120.5 8.4 5.3e-35 120.5 5.8 1.9 2 0 0 2 2 2 1 Prp31 C terminal domain Nop PF01798.13 EMG50742.1 - 5.4e-30 103.6 0.8 1.3e-29 102.4 0.1 2.0 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 EMG50742.1 - 6.3e-15 54.7 6.6 2.2e-14 52.9 1.5 2.7 2 0 0 2 2 2 1 NOSIC (NUC001) domain BRE PF06113.7 EMG50742.1 - 0.052 12.5 0.2 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) DUF760 PF05542.6 EMG50742.1 - 8.4 6.6 7.9 29 4.9 1.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF760) tRNA-synt_1 PF00133.17 EMG50743.1 - 3.7e-225 748.5 0.5 3.7e-225 748.5 0.4 2.7 3 1 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EMG50743.1 - 1.7e-35 122.0 0.1 1.7e-35 122.0 0.1 2.2 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EMG50743.1 - 3.2e-20 72.1 0.4 2e-10 39.9 0.1 4.7 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EMG50743.1 - 3.8e-09 36.1 12.4 3.5e-07 29.7 0.0 3.6 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EMG50743.1 - 0.042 12.9 2.2 0.41 9.7 0.0 2.8 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain DUF2342 PF10103.4 EMG50743.1 - 0.063 12.2 0.2 0.12 11.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2342) tRNA-synt_1c PF00749.16 EMG50743.1 - 0.18 10.3 11.9 3.9 6.0 0.0 4.3 4 0 0 4 4 4 0 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1b PF00579.20 EMG50743.1 - 6 5.8 13.5 0.4 9.7 0.0 3.7 4 0 0 4 4 4 0 tRNA synthetases class I (W and Y) tRNA_m1G_MT PF01746.16 EMG50745.1 - 6.1e-30 104.2 0.1 6.1e-30 104.2 0.1 1.5 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase Rad4 PF03835.10 EMG50746.1 - 7.7e-09 35.1 0.8 1.7e-08 33.9 0.6 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EMG50746.1 - 7.3e-05 22.9 0.8 0.00032 20.8 0.6 2.0 1 1 0 1 1 1 1 Transglutaminase-like superfamily Desulfoferrod_N PF06397.7 EMG50746.1 - 0.024 13.9 0.5 0.058 12.7 0.3 1.5 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain CPL PF08144.6 EMG50747.1 - 1.9e-12 47.2 1.9 4.3e-12 46.0 0.1 2.7 2 0 0 2 2 2 1 CPL (NUC119) domain PUF PF00806.14 EMG50747.1 - 0.00013 21.2 2.0 5.8 6.6 0.0 5.6 6 0 0 6 6 6 2 Pumilio-family RNA binding repeat Daxx PF03344.10 EMG50747.1 - 0.34 9.3 20.7 0.49 8.8 14.3 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EMG50747.1 - 0.89 7.3 26.6 0.099 10.5 15.4 1.7 2 0 0 2 2 2 0 Nop14-like family Pex2_Pex12 PF04757.9 EMG50748.1 - 1.9e-37 128.8 8.0 2.5e-37 128.5 5.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.1 EMG50748.1 - 8.2e-06 25.4 4.2 1.6e-05 24.4 2.9 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMG50748.1 - 2.2e-05 24.3 3.5 0.00025 20.9 1.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMG50748.1 - 0.00025 20.6 4.7 0.00042 19.9 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMG50748.1 - 0.0032 17.3 3.0 0.0032 17.3 2.1 1.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EMG50748.1 - 0.0047 16.7 4.4 0.018 14.8 3.0 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMG50748.1 - 0.0074 15.9 3.7 0.018 14.7 2.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMG50748.1 - 0.011 15.4 0.2 0.031 13.9 0.2 1.9 1 1 0 1 1 1 0 RING-type zinc-finger Pkinase PF00069.20 EMG50749.1 - 1.5e-64 217.6 0.1 4.1e-64 216.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50749.1 - 2.3e-50 171.0 0.1 8.8e-50 169.1 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG50749.1 - 0.001 18.1 0.0 0.0019 17.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EMG50749.1 - 0.021 14.1 0.1 0.049 12.9 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 EMG50749.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EMG50749.1 - 0.14 11.2 0.0 0.29 10.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Epimerase PF01370.16 EMG50750.1 - 1.6e-16 60.4 0.0 2.1e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMG50750.1 - 3e-14 52.4 0.0 4.3e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMG50750.1 - 3.6e-10 40.1 0.6 1.2e-09 38.4 0.4 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMG50750.1 - 4.3e-07 29.1 0.2 1.3e-06 27.5 0.1 1.8 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EMG50750.1 - 4.8e-06 26.6 0.0 8.7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EMG50750.1 - 1.2e-05 24.4 0.2 2.3e-05 23.4 0.1 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 EMG50750.1 - 0.00017 21.3 0.0 0.00033 20.3 0.0 1.5 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 EMG50750.1 - 0.0014 19.0 0.0 0.0032 17.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Zeta_toxin PF06414.7 EMG50750.1 - 0.0014 17.7 0.0 0.0039 16.3 0.0 1.8 1 1 0 1 1 1 1 Zeta toxin NmrA PF05368.8 EMG50750.1 - 0.0027 16.9 0.7 0.015 14.5 0.2 2.2 2 1 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.12 EMG50750.1 - 0.024 13.5 0.0 0.21 10.4 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain DapB_N PF01113.15 EMG50750.1 - 0.072 13.0 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.21 EMG50751.1 - 7.4e-23 80.5 0.0 1.1e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMG50751.1 - 0.0042 17.9 0.0 0.0089 16.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Nucleoporin_C PF03177.9 EMG50752.1 - 1.5e-62 211.9 15.3 2.5e-62 211.2 10.6 1.3 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EMG50752.1 - 6e-60 203.1 3.8 1.4e-59 201.9 2.7 1.7 1 0 0 1 1 1 1 Nup133 N terminal like Brix PF04427.13 EMG50752.1 - 1.6e-35 122.4 3.1 4.7e-35 120.9 2.2 1.8 1 0 0 1 1 1 1 Brix domain DASH_Dad2 PF08654.5 EMG50753.1 - 6.8e-26 90.2 3.2 1.6e-25 89.0 2.2 1.7 1 1 0 1 1 1 1 DASH complex subunit Dad2 Baculo_PEP_C PF04513.7 EMG50753.1 - 0.00049 19.9 1.2 0.00058 19.6 0.8 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Duo1 PF08651.5 EMG50753.1 - 0.0011 18.4 0.6 0.002 17.6 0.4 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 NPV_P10 PF05531.7 EMG50753.1 - 0.029 14.5 1.4 0.029 14.5 1.0 1.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein P_gingi_FimA PF06321.6 EMG50753.1 - 0.11 11.6 1.0 0.15 11.2 0.7 1.3 1 1 0 1 1 1 0 Major fimbrial subunit protein (FimA) WEMBL PF05701.6 EMG50754.1 - 0.00046 18.7 0.2 0.00071 18.1 0.1 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light FliJ PF02050.11 EMG50754.1 - 0.0094 15.9 3.8 0.047 13.7 1.3 2.4 2 1 1 3 3 3 2 Flagellar FliJ protein DUF489 PF04356.7 EMG50754.1 - 0.067 12.7 2.8 0.14 11.7 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DASH_Dad4 PF08650.5 EMG50754.1 - 0.077 12.9 6.1 0.22 11.4 4.3 1.9 1 0 0 1 1 1 0 DASH complex subunit Dad4 Pox_A_type_inc PF04508.7 EMG50754.1 - 0.087 12.6 3.2 5.8 6.9 0.2 3.6 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat FlaC_arch PF05377.6 EMG50754.1 - 0.13 12.1 4.5 0.41 10.5 3.1 2.0 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) IncA PF04156.9 EMG50754.1 - 0.26 10.8 3.3 0.47 10.0 2.3 1.4 1 0 0 1 1 1 0 IncA protein Sugarporin_N PF11471.3 EMG50754.1 - 0.35 10.5 5.7 0.75 9.4 3.9 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Mod_r PF07200.8 EMG50754.1 - 0.67 9.8 14.0 0.087 12.7 5.3 2.5 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF3450 PF11932.3 EMG50754.1 - 1.4 8.1 8.6 1.2 8.3 4.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ATG16 PF08614.6 EMG50754.1 - 3.9 7.2 15.9 0.15 11.8 5.1 2.3 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.3 EMG50754.1 - 4.6 7.1 10.8 0.16 11.7 2.1 2.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Shugoshin_C PF07557.6 EMG50754.1 - 7.1 6.2 8.7 26 4.3 6.0 2.1 1 1 0 1 1 1 0 Shugoshin C terminus Thymidylat_synt PF00303.14 EMG50755.1 - 5.5e-119 396.1 0.0 6.2e-119 395.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase HSP9_HSP12 PF04119.7 EMG50756.1 - 4.7e-24 84.2 6.5 5.2e-24 84.0 4.5 1.0 1 0 0 1 1 1 1 Heat shock protein 9/12 MT0933_antitox PF14013.1 EMG50756.1 - 0.65 10.1 6.6 1.3 9.1 4.6 1.6 1 1 0 1 1 1 0 MT0933-like antitoxin protein 4HBT PF03061.17 EMG50757.1 - 1.8e-06 27.9 0.0 2.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF3918 PF13056.1 EMG50757.1 - 0.034 13.4 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) Peroxin-22 PF12827.2 EMG50758.1 - 5.6e-33 113.1 1.9 6.7e-33 112.8 1.0 1.4 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family DUF2140 PF09911.4 EMG50758.1 - 0.036 13.2 2.0 0.083 12.0 0.7 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) FBA_2 PF07735.12 EMG50758.1 - 0.71 9.7 10.9 3.7 7.4 1.4 2.7 2 1 0 2 2 2 0 F-box associated Grp1_Fun34_YaaH PF01184.14 EMG50759.1 - 1.9e-91 305.0 17.3 2.2e-91 304.8 12.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3784 PF12650.2 EMG50759.1 - 3.1 7.8 11.8 0.6 10.0 3.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) Sugar_tr PF00083.19 EMG50760.1 - 1.9e-149 498.0 35.9 2.2e-149 497.8 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG50760.1 - 1.7e-29 102.6 33.3 2.2e-27 95.7 13.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3321 PF11968.3 EMG50761.1 - 1.4e-91 306.0 0.0 1.5e-91 305.8 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EMG50761.1 - 9.1e-05 22.2 0.0 0.00015 21.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain DEAD PF00270.24 EMG50762.1 - 1.2e-38 132.3 0.0 3e-38 130.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG50762.1 - 1.8e-24 85.4 0.0 4.1e-24 84.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EMG50762.1 - 0.028 14.5 1.8 0.065 13.3 0.2 2.5 2 1 0 2 2 2 0 AAA domain Mig-14 PF07395.6 EMG50762.1 - 0.028 13.4 0.7 0.068 12.1 0.1 1.9 2 0 0 2 2 2 0 Mig-14 eRF1_2 PF03464.10 EMG50763.1 - 7.5e-47 158.9 0.2 1.3e-46 158.1 0.2 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EMG50763.1 - 8e-37 125.9 0.1 1.9e-36 124.7 0.1 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EMG50763.1 - 1.4e-26 92.5 0.1 5.2e-26 90.7 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 1 CDC50 PF03381.10 EMG50764.1 - 5.9e-90 301.1 0.5 5.9e-90 301.1 0.3 1.4 2 0 0 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family ADH_zinc_N PF00107.21 EMG50765.1 - 6.6e-22 77.4 0.0 1.2e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMG50765.1 - 0.00026 21.8 0.0 0.0011 19.9 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PLA2_B PF01735.13 EMG50767.1 - 5.7e-183 608.5 16.5 9.3e-92 307.7 2.0 2.0 1 1 1 2 2 2 2 Lysophospholipase catalytic domain ParBc PF02195.13 EMG50768.1 - 3.5e-13 49.4 0.0 4e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain NAD_binding_6 PF08030.7 EMG50769.1 - 4e-25 88.5 0.1 1.1e-24 87.0 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMG50769.1 - 6e-22 77.4 0.0 1.1e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EMG50769.1 - 1.1e-15 57.7 19.3 2.8e-15 56.5 12.0 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EMG50769.1 - 7e-06 26.5 0.0 0.00015 22.3 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Sugar_tr PF00083.19 EMG50771.1 - 2.1e-116 389.1 33.8 2.7e-116 388.8 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG50771.1 - 5.1e-29 101.1 41.1 6.6e-29 100.7 20.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 EMG50772.1 - 6.3e-67 225.4 0.0 9e-67 224.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50772.1 - 9.6e-32 110.0 0.0 1.6e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMG50772.1 - 0.0027 16.7 0.0 0.0056 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMG50772.1 - 0.0052 15.7 0.0 0.011 14.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EMG50772.1 - 0.16 11.6 0.1 0.29 10.8 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L18e PF00828.14 EMG50773.1 - 1.2e-17 64.4 0.5 2.7e-17 63.3 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Feld-I_B PF09252.5 EMG50773.1 - 0.086 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Allergen Fel d I-B chain Pkinase PF00069.20 EMG50774.1 - 1.9e-53 181.2 0.0 2.3e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50774.1 - 4.8e-16 58.6 0.0 1.3e-15 57.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EMG50774.1 - 2.7e-06 27.3 0.0 2.9e-05 23.9 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMG50774.1 - 0.0032 17.0 0.2 0.0067 16.0 0.1 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 EMG50774.1 - 0.021 13.6 0.0 0.041 12.7 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 CH PF00307.26 EMG50775.1 - 2.3e-12 46.8 9.9 3.6e-11 43.0 0.1 4.1 3 2 0 3 3 3 2 Calponin homology (CH) domain Baculo_PEP_C PF04513.7 EMG50775.1 - 4.2 7.1 8.5 0.25 11.1 0.7 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2340 PF10209.4 EMG50776.1 - 1.3e-56 189.9 0.7 1.5e-56 189.7 0.5 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) DUF4177 PF13783.1 EMG50776.1 - 0.0069 15.9 0.1 0.016 14.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4177) Cytochrom_C1 PF02167.10 EMG50777.1 - 4.4e-82 274.9 0.0 5.3e-82 274.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EMG50777.1 - 0.0031 17.6 0.0 0.0064 16.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EMG50777.1 - 0.061 14.1 0.2 0.14 13.0 0.1 1.7 1 1 0 1 1 1 0 Cytochrome c Ras PF00071.17 EMG50778.1 - 3.6e-58 195.5 0.0 4.2e-58 195.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMG50778.1 - 2.8e-16 60.0 0.0 3.8e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMG50778.1 - 6.4e-09 35.2 0.0 1.1e-08 34.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMG50778.1 - 0.0012 18.1 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EMG50778.1 - 0.0012 18.3 0.0 0.024 14.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMG50778.1 - 0.0071 16.2 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMG50778.1 - 0.0073 15.4 0.0 0.0083 15.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arch_ATPase PF01637.13 EMG50778.1 - 0.017 14.8 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 EMG50778.1 - 0.026 14.8 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter G-alpha PF00503.15 EMG50778.1 - 0.11 11.2 0.0 0.13 10.9 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit DUF3128 PF11326.3 EMG50779.1 - 9.1e-30 102.6 1.6 9.6e-30 102.5 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) Plasmodium_Vir PF05795.6 EMG50781.1 - 0.0011 18.2 0.2 0.0011 18.2 0.1 1.5 2 0 0 2 2 2 1 Plasmodium vivax Vir protein Glycophorin_A PF01102.13 EMG50781.1 - 0.083 12.6 0.2 0.083 12.6 0.1 2.2 3 0 0 3 3 3 0 Glycophorin A FAD_binding_8 PF08022.7 EMG50782.1 - 1.3e-23 82.8 0.0 3e-23 81.6 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EMG50782.1 - 1.8e-22 79.9 0.0 2.8e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMG50782.1 - 1.4e-18 67.1 9.9 1.4e-18 67.1 6.9 2.3 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EMG50782.1 - 0.0086 16.6 0.1 0.25 11.9 0.0 2.7 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain DUF500 PF04366.7 EMG50783.1 - 7.8e-09 35.0 0.4 1.3e-08 34.3 0.3 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) zf-C2H2 PF00096.21 EMG50784.1 - 1.3e-34 116.4 64.9 3.7e-06 26.9 1.4 9.4 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMG50784.1 - 2.3e-25 87.0 56.6 9e-05 22.5 0.7 9.3 9 0 0 9 9 9 8 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMG50784.1 - 1.4e-19 69.3 64.4 1.5e-06 28.1 0.6 10.3 9 1 1 10 10 10 7 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMG50784.1 - 2e-11 43.6 31.2 0.1 12.7 0.3 8.5 8 1 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMG50784.1 - 2.7e-09 36.8 23.8 0.11 12.7 0.6 7.6 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMG50784.1 - 0.0045 16.8 0.6 0.0045 16.8 0.4 5.7 6 0 0 6 6 6 1 C2H2-type zinc finger IBR PF01485.16 EMG50784.1 - 0.013 15.3 1.9 0.013 15.3 1.3 5.3 3 2 1 4 4 4 0 IBR domain zf-FCS PF06467.9 EMG50784.1 - 0.069 12.8 0.6 0.069 12.8 0.4 4.9 5 1 0 5 5 5 0 MYM-type Zinc finger with FCS sequence motif Tho2 PF11262.3 EMG50785.1 - 1.8e-73 247.1 9.7 1.8e-73 247.1 6.7 3.2 3 0 0 3 3 3 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EMG50785.1 - 2.2e-24 85.0 0.1 6.1e-24 83.6 0.1 1.9 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Tim17 PF02466.14 EMG50786.1 - 7.8e-31 106.7 6.8 9.7e-31 106.4 4.7 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3180 PF11377.3 EMG50786.1 - 5.5 6.8 8.1 9 6.1 0.4 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3180) Pkinase PF00069.20 EMG50787.1 - 8.3e-67 225.0 0.0 1.5e-66 224.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50787.1 - 3.3e-49 167.2 0.0 7.1e-49 166.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG50787.1 - 2.5e-08 33.2 0.1 1.9e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EMG50787.1 - 0.026 14.2 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EMG50787.1 - 0.038 13.0 0.0 0.14 11.1 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mg_trans_NIPA PF05653.9 EMG50788.1 - 0.003 16.5 26.9 0.013 14.5 7.5 2.4 2 1 0 3 3 3 2 Magnesium transporter NIPA RNA_pol_Rpb2_6 PF00562.23 EMG50788.1 - 0.025 13.3 0.0 0.039 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 Tir_receptor_C PF07489.6 EMG50788.1 - 0.79 9.4 4.3 3.4 7.3 0.3 2.4 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus SpoU_methylase PF00588.14 EMG50789.1 - 4.1e-27 94.7 0.0 5.3e-26 91.2 0.0 2.2 2 0 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EMG50789.1 - 1.3e-10 41.3 0.1 3.7e-10 39.8 0.1 1.9 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding DUF676 PF05057.9 EMG50790.1 - 6.4e-40 136.7 0.0 1e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EMG50790.1 - 0.0013 18.3 0.0 0.0027 17.3 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein SHP PF03579.8 EMG50790.1 - 0.018 14.3 0.3 0.036 13.4 0.2 1.5 1 0 0 1 1 1 0 Small hydrophobic protein Lipase_3 PF01764.20 EMG50790.1 - 0.02 14.5 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.2 EMG50790.1 - 0.038 13.7 0.0 0.096 12.4 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMG50790.1 - 0.13 12.1 0.0 0.46 10.3 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family SH3_1 PF00018.23 EMG50791.1 - 2.9e-16 58.5 0.1 5e-16 57.8 0.1 1.4 1 0 0 1 1 1 1 SH3 domain DUF500 PF04366.7 EMG50791.1 - 5.6e-15 54.9 0.0 9.6e-15 54.1 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_9 PF14604.1 EMG50791.1 - 3.1e-12 45.8 0.1 5.8e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMG50791.1 - 3.6e-11 42.3 0.0 7.1e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain AA_permease_2 PF13520.1 EMG50792.1 - 1.9e-50 171.6 50.6 2.5e-50 171.2 35.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMG50792.1 - 6.2e-34 117.1 44.0 8.4e-34 116.7 30.5 1.0 1 0 0 1 1 1 1 Amino acid permease Ribosomal_L1 PF00687.16 EMG50793.1 - 3.3e-33 114.8 11.2 4e-31 108.0 7.8 2.0 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family GST_C PF00043.20 EMG50794.1 - 9.3e-17 60.8 0.0 1.5e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMG50794.1 - 4e-14 52.5 0.0 7.5e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMG50794.1 - 1.2e-11 44.4 0.0 2.3e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMG50794.1 - 2.4e-10 40.4 0.0 4.9e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMG50794.1 - 0.021 14.7 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1387 PF07139.6 EMG50794.1 - 0.28 10.7 5.0 0.41 10.1 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) NPCC PF08058.6 EMG50795.1 - 1.4e-34 118.9 0.8 1.4e-34 118.9 0.6 1.9 2 0 0 2 2 2 1 Nuclear pore complex component CRF PF00473.12 EMG50795.1 - 0.31 11.1 0.0 0.31 11.1 0.0 2.6 2 0 0 2 2 2 0 Corticotropin-releasing factor family IGPD PF00475.13 EMG50796.1 - 2.3e-60 202.6 0.7 4.2e-60 201.8 0.5 1.4 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Arena_RNA_pol PF06317.6 EMG50796.1 - 0.083 9.4 0.0 0.11 9.1 0.0 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase DUF3722 PF12519.3 EMG50797.1 - 4.2e-70 235.9 1.6 4.2e-70 235.9 1.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3722) APG5 PF04106.7 EMG50797.1 - 0.071 12.5 0.6 0.38 10.1 0.4 2.0 1 1 0 1 1 1 0 Autophagy protein Apg5 Mit_ribos_Mrp51 PF11709.3 EMG50798.1 - 5.4e-96 321.5 3.0 6.2e-96 321.3 2.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit BSD PF03909.12 EMG50798.1 - 0.024 14.3 0.1 0.057 13.1 0.1 1.6 1 0 0 1 1 1 0 BSD domain DUF605 PF04652.11 EMG50799.1 - 0.0012 18.2 44.6 0.0012 18.2 30.9 4.1 3 1 1 4 4 4 1 Vta1 like DUF2420 PF10336.4 EMG50800.1 - 1.8e-24 85.4 5.9 1.8e-24 85.4 4.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2420) GTP_EFTU PF00009.22 EMG50801.1 - 9.9e-32 109.8 0.5 2.3e-31 108.6 0.4 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EMG50801.1 - 2.3e-20 72.3 0.0 4.3e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 EMG50801.1 - 8.3e-10 38.6 0.1 1.7e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_C PF00679.19 EMG50801.1 - 1.5e-07 31.1 0.0 5.1e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 EMG50801.1 - 2.3e-06 27.5 1.3 5e-06 26.4 0.2 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EMG50801.1 - 4.6e-05 23.8 0.5 0.00011 22.6 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 EMG50801.1 - 0.0049 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EMG50801.1 - 0.019 14.4 0.3 0.056 12.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain EFG_II PF14492.1 EMG50801.1 - 0.021 14.6 0.0 0.075 12.8 0.0 1.9 1 0 0 1 1 1 0 Elongation Factor G, domain II cobW PF02492.14 EMG50801.1 - 0.024 14.0 0.4 2.7 7.4 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.17 EMG50801.1 - 0.026 13.9 0.1 0.071 12.5 0.1 1.7 1 1 0 1 1 1 0 Ras family RNA_pol_Rpb4 PF03874.11 EMG50802.1 - 2.5e-30 104.8 11.4 9.5e-30 103.0 7.9 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb4 CENP-B_dimeris PF09026.5 EMG50802.1 - 0.0031 17.7 2.6 0.035 14.3 2.1 2.1 2 0 0 2 2 2 1 Centromere protein B dimerisation domain GRP PF07172.6 EMG50802.1 - 0.017 15.6 0.3 0.029 14.8 0.2 1.5 1 0 0 1 1 1 0 Glycine rich protein family DUF2457 PF10446.4 EMG50802.1 - 0.13 11.0 5.8 0.17 10.5 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Prothymosin PF03247.9 EMG50802.1 - 0.14 12.2 12.7 0.069 13.3 6.8 1.9 2 0 0 2 2 2 0 Prothymosin/parathymosin family EBV-NA3 PF05009.7 EMG50802.1 - 0.24 10.6 1.4 0.36 10.0 1.0 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) NOA36 PF06524.7 EMG50802.1 - 0.29 10.3 2.9 0.44 9.7 2.0 1.3 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.20 EMG50803.1 - 1.4e-53 181.7 0.1 4.4e-52 176.7 0.1 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50803.1 - 7.4e-22 77.6 0.0 1.6e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMG50803.1 - 0.00012 21.9 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMG50803.1 - 0.0011 18.5 0.7 0.0034 17.0 0.5 1.8 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EMG50803.1 - 0.018 14.3 1.2 0.027 13.8 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.9 EMG50803.1 - 0.024 13.7 0.0 0.05 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SWIRM PF04433.12 EMG50804.1 - 6.5e-32 109.5 0.1 1.7e-31 108.1 0.1 1.8 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.1 EMG50804.1 - 5e-09 36.1 0.1 1.9e-08 34.3 0.1 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EMG50804.1 - 3.7e-08 33.3 0.0 1e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF1014 PF06244.7 EMG50805.1 - 1.1e-28 99.9 0.6 1.7e-28 99.2 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1014) HMG_box PF00505.14 EMG50805.1 - 0.027 14.7 0.1 0.056 13.7 0.1 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box Phytochelatin PF05023.9 EMG50805.1 - 0.1 11.5 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Phytochelatin synthase UcrQ PF02939.11 EMG50806.1 - 2.3e-29 101.0 1.1 2.7e-29 100.8 0.8 1.0 1 0 0 1 1 1 1 UcrQ family Ribosomal_L22 PF00237.14 EMG50807.1 - 1.4e-32 111.7 0.2 2.3e-32 111.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF2960 PF11173.3 EMG50807.1 - 0.15 12.3 0.2 0.44 10.8 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2960) DUF3535 PF12054.3 EMG50808.1 - 2.1e-141 471.5 4.6 1.6e-140 468.6 1.1 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EMG50808.1 - 2.4e-76 256.3 0.1 4.3e-76 255.5 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 EMG50808.1 - 4.2e-16 57.5 3.3 0.54 10.4 0.0 9.6 9 0 0 9 9 9 5 HEAT repeat Helicase_C PF00271.26 EMG50808.1 - 1.7e-13 50.1 0.0 3.8e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_EZ PF13513.1 EMG50808.1 - 9.3e-09 35.5 4.7 1.1 9.7 0.0 9.2 9 1 1 10 10 10 1 HEAT-like repeat HEAT_2 PF13646.1 EMG50808.1 - 2.3e-08 34.1 2.8 0.0037 17.5 0.0 6.7 5 2 1 6 6 6 1 HEAT repeats Vac14_Fab1_bd PF12755.2 EMG50808.1 - 2.1e-07 31.2 0.1 0.015 15.6 0.0 5.5 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region Mito_carr PF00153.22 EMG50809.1 - 5.8e-75 247.1 2.2 1.8e-25 88.4 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein NpwBP PF12622.2 EMG50810.1 - 1.5e-09 38.2 11.9 3.2e-09 37.1 0.0 3.1 2 1 1 3 3 3 2 mRNA biogenesis factor Cytokin-bind PF09265.5 EMG50810.1 - 0.067 12.3 3.9 0.093 11.8 2.7 1.1 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding UPF0016 PF01169.14 EMG50811.1 - 7.8e-40 134.8 21.5 6e-21 74.3 3.6 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.11 EMG50811.1 - 0.2 11.0 13.7 0.085 12.2 2.6 2.6 2 1 0 2 2 2 0 Integral membrane protein TerC family Complex1_51K PF01512.12 EMG50812.1 - 2.7e-46 157.0 0.0 7.2e-46 155.6 0.0 1.7 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EMG50812.1 - 1.7e-19 68.6 0.7 3.6e-19 67.6 0.5 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EMG50812.1 - 9.9e-08 31.7 0.0 2.9e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 SLBB domain Glyco_transf_15 PF01793.11 EMG50813.1 - 5.4e-133 443.0 12.4 6.6e-133 442.7 8.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ebp2 PF05890.7 EMG50814.1 - 1e-89 300.4 21.1 1e-89 300.4 14.6 2.4 1 1 2 3 3 3 1 Eukaryotic rRNA processing protein EBP2 polyprenyl_synt PF00348.12 EMG50815.1 - 1.3e-78 263.4 0.0 1.6e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase nsp8 PF08717.5 EMG50815.1 - 0.12 11.9 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 nsp8 replicase HMGL-like PF00682.14 EMG50816.1 - 4e-50 170.6 0.7 7.3e-50 169.8 0.2 1.6 2 0 0 2 2 2 1 HMGL-like FliG_N PF14842.1 EMG50816.1 - 0.028 14.5 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 FliG N-terminal domain ADH_N PF08240.7 EMG50817.1 - 7.6e-23 80.3 0.1 1.1e-22 79.8 0.1 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMG50817.1 - 1.8e-10 40.4 0.0 5.4e-09 35.6 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EMG50817.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain zf-CXXC PF02008.15 EMG50817.1 - 0.022 14.5 1.8 0.041 13.7 1.2 1.4 1 0 0 1 1 1 0 CXXC zinc finger domain Myb_DNA-binding PF00249.26 EMG50818.1 - 9.2e-09 35.2 1.1 1.7e-08 34.4 0.8 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMG50818.1 - 0.00021 21.3 0.0 0.00057 19.9 0.0 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain DUF605 PF04652.11 EMG50818.1 - 0.65 9.3 17.2 0.67 9.2 11.9 1.1 1 0 0 1 1 1 0 Vta1 like Thiolase_N PF00108.18 EMG50819.1 - 1.6e-99 332.2 1.5 2e-99 331.8 1.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMG50819.1 - 6.2e-43 145.1 0.6 6.2e-43 145.1 0.4 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EMG50819.1 - 4.7e-05 23.0 0.8 8.6e-05 22.1 0.6 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SGT1 PF07093.6 EMG50820.1 - 2e-22 79.3 37.5 1.5e-21 76.4 26.0 1.9 1 1 0 1 1 1 1 SGT1 protein Spt5_N PF11942.3 EMG50820.1 - 8 7.1 34.5 5.3 7.7 13.3 2.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal adh_short PF00106.20 EMG50821.1 - 1.5e-09 38.0 0.0 2.7e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMG50821.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 KR domain SUV3_C PF12513.3 EMG50822.1 - 3e-14 52.2 0.4 7e-14 51.0 0.3 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EMG50822.1 - 3.9e-11 42.6 0.0 1e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SKI PF01202.17 EMG50822.1 - 6.1e-11 42.4 0.0 3e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 Shikimate kinase AAA_17 PF13207.1 EMG50822.1 - 1.7e-07 32.0 0.1 8.6e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMG50822.1 - 2e-07 31.3 0.0 9.2e-07 29.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMG50822.1 - 2.6e-07 30.5 0.0 1.6e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EMG50822.1 - 0.0048 17.0 0.2 0.084 13.0 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 EMG50822.1 - 0.01 15.5 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase SopE_GEF PF07487.8 EMG50822.1 - 0.012 15.6 0.0 2 8.3 0.0 2.6 2 0 0 2 2 2 0 SopE GEF domain AAA_16 PF13191.1 EMG50822.1 - 0.014 15.4 0.1 0.41 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain PhoH PF02562.11 EMG50822.1 - 0.014 14.5 0.1 2.8 7.1 0.1 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.1 EMG50822.1 - 0.02 15.0 0.2 0.65 10.1 0.0 3.2 4 0 0 4 4 3 0 AAA domain AAA_30 PF13604.1 EMG50822.1 - 0.02 14.4 0.1 0.13 11.7 0.0 2.1 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.7 EMG50822.1 - 0.031 13.3 0.1 0.28 10.2 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 EMG50822.1 - 0.076 12.7 0.1 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 EMG50822.1 - 0.17 10.7 0.2 6.2 5.6 0.1 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein MobB PF03205.9 EMG50822.1 - 0.23 11.1 2.2 13 5.5 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Pkinase PF00069.20 EMG50823.1 - 2.2e-67 226.9 0.2 2.2e-67 226.9 0.1 2.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50823.1 - 1.6e-39 135.5 0.0 2.9e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG50823.1 - 1.3e-05 24.3 2.7 1.9e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Mur_ligase_M PF08245.7 EMG50824.1 - 0.00012 22.2 0.5 0.0023 18.0 0.4 2.8 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EMG50824.1 - 0.00094 19.1 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Cyclin PF08613.6 EMG50826.1 - 0.61 10.4 5.2 4.1 7.8 3.7 2.2 1 1 0 1 1 1 0 Cyclin WD40 PF00400.27 EMG50827.1 - 8.6e-40 133.2 19.8 2.1e-06 27.3 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat YEATS PF03366.11 EMG50828.1 - 4.4e-27 93.6 0.1 8.4e-27 92.7 0.1 1.5 1 0 0 1 1 1 1 YEATS family Aminotran_4 PF01063.14 EMG50829.1 - 8.5e-33 113.7 0.0 1.1e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Mo25 PF08569.6 EMG50830.1 - 3.3e-128 427.4 14.8 3.7e-128 427.2 10.3 1.0 1 0 0 1 1 1 1 Mo25-like EAP30 PF04157.11 EMG50831.1 - 2.6e-41 141.2 0.4 5.2e-41 140.2 0.3 1.5 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EMG50831.1 - 1.2e-27 95.5 0.8 2.6e-27 94.4 0.5 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 DZR PF12773.2 EMG50831.1 - 0.0052 16.5 0.4 0.0052 16.5 0.3 2.2 1 1 1 2 2 2 2 Double zinc ribbon zf-RanBP PF00641.13 EMG50831.1 - 0.016 14.2 2.1 0.016 14.2 1.5 3.0 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others GRAM PF02893.15 EMG50831.1 - 0.036 13.5 0.0 0.1 12.1 0.0 1.8 1 0 0 1 1 1 0 GRAM domain Fe-ADH_2 PF13685.1 EMG50831.1 - 0.062 12.5 0.1 0.19 10.9 0.0 1.8 1 1 1 2 2 2 0 Iron-containing alcohol dehydrogenase DUF35_N PF12172.3 EMG50831.1 - 0.34 10.8 1.5 1.1 9.2 0.1 2.1 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-ribbon_3 PF13248.1 EMG50831.1 - 1.4 8.1 8.4 0.6 9.4 1.6 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Pkinase PF00069.20 EMG50832.1 - 7.5e-86 287.4 3.0 5.3e-58 196.2 0.1 4.7 5 1 0 5 5 5 3 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50832.1 - 1.9e-43 148.3 4.0 5.2e-27 94.5 0.0 4.2 4 0 0 4 4 4 2 Protein tyrosine kinase Kinase-like PF14531.1 EMG50832.1 - 0.00016 20.7 0.0 0.036 13.0 0.0 2.8 3 0 0 3 3 3 2 Kinase-like Pkinase PF00069.20 EMG50833.1 - 6.6e-62 209.0 0.9 1.8e-61 207.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50833.1 - 5.3e-23 81.4 2.0 6.8e-22 77.7 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG50833.1 - 0.00014 20.9 0.0 0.00029 19.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMG50833.1 - 0.011 15.4 0.9 0.031 14.0 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMG50833.1 - 0.011 15.3 0.0 0.011 15.3 0.0 2.8 3 1 0 3 3 3 0 Choline/ethanolamine kinase FLILHELTA PF10306.4 EMG50834.1 - 1.5e-29 101.8 0.6 3.1e-29 100.8 0.2 1.7 2 0 0 2 2 2 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 EMG50834.1 - 0.02 15.1 0.3 0.053 13.8 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) DUF788 PF05620.6 EMG50834.1 - 9.9 5.9 8.0 0.37 10.6 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF788) ADH_N PF08240.7 EMG50835.1 - 1.4e-23 82.7 0.0 1.9e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMG50835.1 - 6.2e-06 25.7 0.0 1.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-CXXC PF02008.15 EMG50835.1 - 0.018 14.8 1.7 0.03 14.1 1.2 1.3 1 0 0 1 1 1 0 CXXC zinc finger domain AlaDh_PNT_C PF01262.16 EMG50835.1 - 0.026 14.1 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Aminotran_3 PF00202.16 EMG50836.1 - 1.5e-84 283.7 0.0 1.8e-84 283.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EMG50836.1 - 0.0012 17.8 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II TRF PF08558.5 EMG50837.1 - 1.3e-76 257.0 0.0 3.1e-76 255.8 0.0 1.6 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Mito_carr PF00153.22 EMG50838.1 - 4.1e-62 205.9 0.3 1.6e-26 91.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein B12D PF06522.6 EMG50838.1 - 1.8e-05 24.3 0.0 4.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit PT-VENN PF04829.8 EMG50838.1 - 0.028 13.9 0.8 6.4 6.4 0.0 2.8 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif DUF1014 PF06244.7 EMG50839.1 - 8e-29 100.3 1.7 1.3e-28 99.6 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1014) HMG_box PF00505.14 EMG50839.1 - 0.03 14.5 0.1 0.07 13.4 0.1 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box Phytochelatin PF05023.9 EMG50839.1 - 0.12 11.3 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Phytochelatin synthase Transcrip_reg PF01709.15 EMG50840.1 - 9.1e-55 185.3 0.6 1e-54 185.1 0.4 1.0 1 0 0 1 1 1 1 Transcriptional regulator DUF1947 PF09183.5 EMG50840.1 - 0.082 12.6 0.0 0.25 11.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) Cas_APE2256 PF09651.5 EMG50840.1 - 0.091 12.4 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) AA_permease_2 PF13520.1 EMG50841.1 - 0.06 11.8 5.3 0.069 11.6 3.7 1.1 1 0 0 1 1 1 0 Amino acid permease DUF485 PF04341.7 EMG50841.1 - 1 9.1 5.5 0.95 9.2 2.2 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Methyltransf_16 PF10294.4 EMG50842.1 - 2.8e-16 59.4 0.0 5e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EMG50842.1 - 0.034 13.8 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EMG50842.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain 4HBT_3 PF13622.1 EMG50843.1 - 2.2e-29 102.9 0.0 2.9e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EMG50843.1 - 1.6e-17 63.3 1.9 1.3e-10 41.0 0.2 3.7 2 1 1 3 3 3 2 Acyl-CoA thioesterase CAF1C_H4-bd PF12265.3 EMG50844.1 - 3.2e-22 78.2 0.1 7.9e-22 76.9 0.1 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 EMG50844.1 - 7.7e-18 63.6 8.6 0.00019 21.2 0.5 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat Mt_ATP-synt_B PF05405.9 EMG50845.1 - 7.7e-51 171.7 10.1 9.1e-51 171.5 7.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) SRX PF09201.5 EMG50845.1 - 0.055 13.1 1.2 0.084 12.5 0.9 1.4 1 0 0 1 1 1 0 SRX DASH_Duo1 PF08651.5 EMG50845.1 - 2.1 7.9 8.9 5.2 6.7 0.3 3.2 2 1 1 3 3 3 0 DASH complex subunit Duo1 cwf18 PF08315.7 EMG50846.1 - 0.026 14.9 11.8 0.33 11.4 8.2 2.1 1 1 0 1 1 1 0 cwf18 pre-mRNA splicing factor Pap_E4 PF02711.9 EMG50846.1 - 0.44 11.3 3.7 0.77 10.6 2.6 1.4 1 0 0 1 1 1 0 E4 protein DUF3070 PF11270.3 EMG50846.1 - 2.2 8.0 4.3 5.3 6.8 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3070) CAML PF14963.1 EMG50846.1 - 2.3 7.5 4.4 2.4 7.4 3.0 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Macoilin PF09726.4 EMG50846.1 - 2.9 6.0 6.2 3.4 5.8 4.3 1.0 1 0 0 1 1 1 0 Transmembrane protein Paramyxo_ncap PF00973.14 EMG50846.1 - 3.7 6.1 6.4 4 6.0 4.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Sec63 PF02889.11 EMG50847.1 - 9.9e-44 149.8 0.1 1.6e-43 149.1 0.1 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EMG50847.1 - 1.9e-27 95.7 0.2 7.8e-27 93.8 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMG50847.1 - 4.1e-12 45.7 0.0 5.4e-11 42.2 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMG50847.1 - 2.6e-10 40.4 0.1 1.1e-09 38.4 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EMG50847.1 - 0.0012 18.9 0.0 0.026 14.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EMG50847.1 - 0.045 12.6 0.0 0.091 11.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein RRM_1 PF00076.17 EMG50848.1 - 2.9e-16 58.8 10.7 1e-10 41.0 0.1 4.7 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG50848.1 - 1.8e-10 40.6 1.7 9.2e-07 28.7 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG50848.1 - 4.4e-07 29.6 6.2 0.014 15.2 0.0 4.1 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sds3 PF08598.6 EMG50849.1 - 5.8e-41 140.2 0.0 5.8e-41 140.2 0.0 3.2 2 1 0 2 2 2 1 Sds3-like MRP-L47 PF06984.8 EMG50849.1 - 0.098 12.5 2.2 5.5 6.9 0.0 3.1 2 0 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) BRCT PF00533.21 EMG50850.1 - 2.1e-13 50.1 0.0 4.7e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EMG50850.1 - 1.7e-07 30.9 0.0 3.1e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain FA_hydroxylase PF04116.8 EMG50852.1 - 1.2e-15 57.9 6.8 1.2e-15 57.9 4.7 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PAS_8 PF13188.1 EMG50852.1 - 0.13 12.2 0.0 4.1 7.4 0.0 2.6 2 0 0 2 2 2 0 PAS domain TRAPP PF04051.11 EMG50853.1 - 1.8e-36 124.9 0.0 2.2e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component TATR PF03430.8 EMG50853.1 - 0.078 11.6 0.0 0.099 11.2 0.0 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Y_phosphatase PF00102.22 EMG50854.1 - 1.4e-61 207.8 1.0 1.9e-61 207.4 0.7 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EMG50854.1 - 9e-05 22.0 0.0 0.0022 17.5 0.0 2.6 2 1 1 3 3 3 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EMG50854.1 - 0.021 14.9 0.2 0.3 11.1 0.0 2.7 2 2 0 2 2 2 0 Inositol hexakisphosphate Oxidored_FMN PF00724.15 EMG50855.1 - 2.7e-89 299.5 0.0 3.1e-89 299.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MGS PF02142.17 EMG50855.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 MGS-like domain zf-AN1 PF01428.11 EMG50856.1 - 4.8e-10 39.1 11.6 7.6e-10 38.5 8.1 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger ubiquitin PF00240.18 EMG50856.1 - 0.00017 20.8 0.2 0.00088 18.6 0.2 2.2 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EMG50856.1 - 0.0019 18.3 0.4 0.0041 17.2 0.3 1.7 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.3 EMG50856.1 - 0.0073 15.9 0.0 0.019 14.6 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Dicty_REP PF05086.7 EMG50856.1 - 0.019 12.7 2.1 0.021 12.6 1.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Fe_dep_repr_C PF02742.10 EMG50856.1 - 0.064 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain NLE PF08154.7 EMG50856.1 - 0.11 12.5 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 NLE (NUC135) domain Nro1 PF12753.2 EMG50857.1 - 6.8e-158 525.8 39.2 9.9e-158 525.3 27.2 1.2 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 Sigma70_ner PF04546.8 EMG50857.1 - 0.002 17.7 11.1 0.002 17.7 7.7 3.6 3 1 0 4 4 4 1 Sigma-70, non-essential region TP_methylase PF00590.15 EMG50858.1 - 4.3e-44 150.7 0.1 6.2e-44 150.2 0.1 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EMG50858.1 - 3.3e-09 36.9 0.0 7.9e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EMG50858.1 - 5.2e-06 25.6 0.6 0.017 14.3 0.0 3.4 3 0 0 3 3 3 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EMG50858.1 - 0.0097 14.8 0.0 0.024 13.6 0.0 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Aminotran_1_2 PF00155.16 EMG50859.1 - 9e-67 225.5 0.0 1e-66 225.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EMG50859.1 - 2e-05 23.8 0.0 3.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EMG50859.1 - 0.00077 17.8 0.0 0.0013 17.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.6 EMG50859.1 - 0.0057 15.0 0.0 0.0077 14.5 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.16 EMG50859.1 - 0.0066 15.6 0.0 0.0095 15.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EMG50859.1 - 0.01 14.5 0.1 0.027 13.1 0.0 1.6 1 1 0 1 1 1 0 Aminotransferase class-V AA_permease_2 PF13520.1 EMG50860.1 - 5e-46 157.1 31.3 5.5e-46 156.9 21.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMG50860.1 - 1.2e-12 46.9 25.8 1.9e-12 46.3 17.9 1.3 1 0 0 1 1 1 1 Amino acid permease CBFD_NFYB_HMF PF00808.18 EMG50861.1 - 2.8e-15 56.0 2.2 4.8e-15 55.3 1.5 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMG50861.1 - 0.0013 18.8 0.1 0.002 18.2 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF3753 PF12575.3 EMG50861.1 - 0.0089 15.8 0.5 0.019 14.7 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3753) DUF1043 PF06295.7 EMG50861.1 - 0.021 14.4 2.7 0.028 14.0 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Tht1 PF04163.7 EMG50861.1 - 0.088 11.1 2.2 0.097 11.0 1.5 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein BSD PF03909.12 EMG50861.1 - 0.8 9.4 4.8 2 8.1 0.3 2.9 2 1 1 3 3 3 0 BSD domain Orthopox_B11R PF07033.6 EMG50861.1 - 1.9 8.0 8.3 0.24 10.9 1.5 2.6 2 2 0 2 2 2 0 Orthopoxvirus B11R protein Abhydrolase_6 PF12697.2 EMG50862.1 - 3.5e-36 125.2 0.0 4.3e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMG50862.1 - 8.2e-21 74.6 0.0 1.4e-20 73.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMG50862.1 - 5.6e-16 58.6 0.0 5.2e-15 55.4 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EMG50862.1 - 2.6e-09 37.0 0.0 3.9e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 EMG50862.1 - 2e-07 31.5 0.0 2.7e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.8 EMG50862.1 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 EMG50862.1 - 0.0023 16.4 0.0 0.007 14.8 0.0 1.6 1 1 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 EMG50862.1 - 0.0069 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 EMG50862.1 - 0.016 14.8 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.6 EMG50862.1 - 0.062 12.3 0.0 1.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF2920 PF11144.3 EMG50862.1 - 0.08 11.9 0.0 0.3 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) DUF2305 PF10230.4 EMG50862.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Esterase PF00756.15 EMG50862.1 - 0.11 11.8 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase TPR_11 PF13414.1 EMG50863.1 - 1.8e-27 94.7 3.7 1.2e-18 66.5 0.1 2.6 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EMG50863.1 - 9.1e-18 63.0 1.3 2.7e-07 29.9 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMG50863.1 - 2e-16 58.4 0.9 5.5e-05 22.7 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMG50863.1 - 1.1e-10 40.7 1.3 7.1e-05 22.6 0.1 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMG50863.1 - 3e-07 29.7 3.0 0.12 12.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMG50863.1 - 5.3e-07 29.4 3.2 0.00018 21.3 0.3 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMG50863.1 - 7.5e-07 29.6 1.2 0.0011 19.5 0.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMG50863.1 - 1.4e-06 28.3 0.1 0.05 14.2 0.0 3.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EMG50863.1 - 7e-06 25.4 0.1 0.18 11.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMG50863.1 - 1.7e-05 25.0 1.4 0.15 12.4 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMG50863.1 - 0.021 15.2 4.0 10 6.8 0.8 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.12 EMG50863.1 - 0.021 15.1 0.1 0.3 11.4 0.0 2.3 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_9 PF13371.1 EMG50863.1 - 0.05 13.4 0.1 0.7 9.7 0.0 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat VPS9 PF02204.13 EMG50864.1 - 1.3e-14 54.0 2.5 2.1e-14 53.3 0.8 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Ank_4 PF13637.1 EMG50864.1 - 5.6e-05 23.5 0.2 1.2 9.7 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMG50864.1 - 7.9e-05 22.9 0.1 1.4 9.3 0.0 3.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMG50864.1 - 0.013 15.6 0.1 1.9 8.8 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeats (many copies) AA_permease_2 PF13520.1 EMG50865.1 - 4.6e-44 150.6 35.1 5.2e-44 150.4 24.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMG50865.1 - 1.6e-10 39.9 29.8 2.1e-10 39.5 20.7 1.1 1 0 0 1 1 1 1 Amino acid permease ADH_zinc_N_2 PF13602.1 EMG50866.1 - 1e-16 61.9 0.0 1.6e-16 61.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EMG50866.1 - 1.2e-09 37.7 0.0 2e-09 37.0 0.0 1.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.14 EMG50866.1 - 0.037 13.0 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short PF00106.20 EMG50866.1 - 0.06 13.2 0.3 0.4 10.5 0.1 2.2 3 0 0 3 3 3 0 short chain dehydrogenase Semialdhyde_dh PF01118.19 EMG50866.1 - 0.065 13.5 0.0 0.094 13.0 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AA_permease_2 PF13520.1 EMG50867.1 - 1.8e-05 23.4 5.9 2.2e-05 23.2 4.1 1.1 1 0 0 1 1 1 1 Amino acid permease Polysacc_synt PF01943.12 EMG50867.1 - 0.08 12.1 4.5 0.12 11.6 0.7 2.0 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein ADH_N PF08240.7 EMG50868.1 - 1.1e-06 28.2 0.0 1.5e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain RRP7 PF12923.2 EMG50870.1 - 1.3e-36 125.5 15.1 2.1e-36 124.8 10.5 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 EMG50870.1 - 0.0028 17.2 0.1 0.7 9.5 0.0 3.0 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF45 PF01863.12 EMG50870.1 - 0.14 11.9 4.9 0.24 11.1 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 PAH PF02671.16 EMG50870.1 - 0.81 9.3 4.7 5.8 6.6 0.0 3.0 2 1 1 3 3 3 0 Paired amphipathic helix repeat HAD PF12710.2 EMG50871.1 - 2.3e-13 50.7 0.1 3.4e-13 50.1 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMG50871.1 - 3.1e-09 36.8 0.2 3.1e-09 36.8 0.1 2.6 2 2 1 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMG50871.1 - 4.8e-08 33.6 0.3 2.6e-06 28.0 0.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMG50871.1 - 9e-07 29.2 0.1 6.7e-06 26.4 0.0 2.4 2 2 1 3 3 3 1 Haloacid dehalogenase-like hydrolase S6PP PF05116.8 EMG50871.1 - 0.03 13.6 0.1 0.16 11.2 0.0 2.0 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Aha1_N PF09229.6 EMG50871.1 - 0.075 12.8 1.3 0.33 10.7 0.1 2.3 1 1 1 2 2 2 0 Activator of Hsp90 ATPase, N-terminal CRAL_TRIO PF00650.15 EMG50872.1 - 3.3e-36 124.1 0.0 5.3e-36 123.4 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMG50872.1 - 1.8e-16 59.9 1.9 4.7e-16 58.6 1.3 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EMG50872.1 - 0.067 13.0 0.0 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain NNMT_PNMT_TEMT PF01234.12 EMG50872.1 - 0.12 11.2 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Aldedh PF00171.17 EMG50873.1 - 1.1e-160 535.0 4.4 2.4e-157 523.9 3.0 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EMG50873.1 - 0.035 13.3 0.0 5.1 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) FAD-oxidase_C PF02913.14 EMG50874.1 - 7e-50 169.6 0.0 2.5e-49 167.8 0.0 1.8 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EMG50874.1 - 4.7e-31 107.1 0.0 1.2e-30 105.8 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain RRN7 PF11781.3 EMG50874.1 - 1.7e-09 36.9 0.1 3.2e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 RabGAP-TBC PF00566.13 EMG50875.1 - 2.7e-39 134.8 0.3 3.9e-39 134.3 0.2 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.17 EMG50876.1 - 1.8e-11 43.4 0.5 0.00039 19.9 0.0 4.1 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMG50876.1 - 2.2e-08 33.7 0.5 5.4e-05 22.9 0.0 3.8 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMG50876.1 - 1.2e-05 25.2 0.1 0.16 11.9 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HSP70 PF00012.15 EMG50877.1 - 4.5e-58 196.6 16.5 4.5e-58 196.6 11.4 2.6 2 1 0 2 2 2 1 Hsp70 protein Polyoma_agno PF01736.11 EMG50878.1 - 0.06 13.0 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 Polyomavirus agnoprotein Pribosyltran PF00156.22 EMG50879.1 - 2.4e-11 43.4 0.1 5e-11 42.3 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Fe-ADH PF00465.14 EMG50879.1 - 0.014 14.0 0.0 0.022 13.4 0.0 1.2 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Mito_fiss_Elm1 PF06258.6 EMG50879.1 - 0.082 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission ELM1 UFD1 PF03152.9 EMG50880.1 - 2.6e-75 251.3 0.0 3.4e-75 251.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF3256 PF11644.3 EMG50880.1 - 0.062 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) IBN_N PF03810.14 EMG50881.1 - 1e-10 41.3 0.9 1.1e-09 38.1 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain YpjP PF14005.1 EMG50881.1 - 0.046 13.4 0.3 0.44 10.3 0.0 2.9 3 0 0 3 3 3 0 YpjP-like protein Hydantoinase_B PF02538.9 EMG50882.1 - 2e-192 640.1 0.0 3.6e-192 639.2 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EMG50882.1 - 2.8e-83 279.3 0.0 5.2e-83 278.4 0.0 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase DUF367 PF04034.8 EMG50882.1 - 6.9e-53 177.6 0.1 1.4e-52 176.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF367) Hydant_A_N PF05378.8 EMG50882.1 - 7.2e-51 172.1 0.9 3.5e-49 166.6 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region RLI PF04068.10 EMG50882.1 - 4.2e-13 48.6 0.2 1.4e-12 47.0 0.3 1.8 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI Ribonuc_red_sm PF00268.16 EMG50884.1 - 2.5e-120 400.7 4.1 3.5e-120 400.2 2.8 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Formyl_trans_N PF00551.14 EMG50885.1 - 9.4e-44 149.1 0.5 1.9e-42 144.8 0.4 2.0 1 1 0 1 1 1 1 Formyl transferase Iso_dh PF00180.15 EMG50886.1 - 1.7e-99 333.0 0.0 2e-99 332.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4591 PF15261.1 EMG50886.1 - 0.092 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4591) Glyco_transf_22 PF03901.12 EMG50887.1 - 4.1e-63 213.8 35.5 5.5e-63 213.4 24.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family AAA PF00004.24 EMG50888.1 - 1.1e-45 155.1 0.1 3.4e-45 153.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EMG50888.1 - 5.8e-09 36.0 0.0 1.2e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EMG50888.1 - 3.1e-08 33.4 0.1 1.3e-07 31.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMG50888.1 - 1.8e-07 31.3 0.0 7.8e-07 29.2 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMG50888.1 - 9.2e-07 29.0 0.6 0.00016 21.8 0.4 2.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMG50888.1 - 2.9e-05 23.9 0.1 0.00011 22.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EMG50888.1 - 5.6e-05 22.1 0.0 0.0001 21.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EMG50888.1 - 0.00021 22.1 0.2 0.0007 20.4 0.0 1.9 2 1 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 EMG50888.1 - 0.00039 19.5 0.0 0.00071 18.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin RuvB_N PF05496.7 EMG50888.1 - 0.00043 19.4 0.0 0.00094 18.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 EMG50888.1 - 0.00073 19.2 0.0 0.0022 17.7 0.0 1.9 2 0 0 2 2 1 1 NTPase NACHT PF05729.7 EMG50888.1 - 0.00092 18.9 0.2 0.056 13.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_3 PF07726.6 EMG50888.1 - 0.0013 18.3 0.0 0.0067 16.0 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EMG50888.1 - 0.0014 18.3 0.1 0.0037 16.9 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EMG50888.1 - 0.0017 18.2 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EMG50888.1 - 0.0033 17.4 0.0 0.0073 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EMG50888.1 - 0.004 17.3 0.0 0.0084 16.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.1 EMG50888.1 - 0.0043 16.4 2.0 0.056 12.8 0.0 2.7 2 1 1 3 3 3 1 AAA domain TIP49 PF06068.8 EMG50888.1 - 0.0051 15.5 0.0 0.011 14.4 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus AAA_24 PF13479.1 EMG50888.1 - 0.0059 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EMG50888.1 - 0.0068 16.7 0.5 0.75 10.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EMG50888.1 - 0.007 15.9 0.1 0.022 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EMG50888.1 - 0.0071 15.5 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 EMG50888.1 - 0.015 14.8 0.0 0.039 13.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.12 EMG50888.1 - 0.015 14.7 0.0 0.038 13.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein UPF0079 PF02367.12 EMG50888.1 - 0.017 14.7 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EMG50888.1 - 0.02 14.6 1.3 0.19 11.4 0.0 2.7 2 1 1 3 3 3 0 Archaeal ATPase Sigma54_activat PF00158.21 EMG50888.1 - 0.023 14.1 0.2 0.28 10.6 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain NUDE_C PF04880.8 EMG50888.1 - 0.038 14.3 0.2 0.066 13.5 0.2 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Bac_DnaA PF00308.13 EMG50888.1 - 0.04 13.5 0.1 0.09 12.4 0.0 1.6 2 0 0 2 2 1 0 Bacterial dnaA protein AAA_18 PF13238.1 EMG50888.1 - 0.041 14.1 0.1 0.16 12.3 0.0 2.1 2 1 0 2 2 1 0 AAA domain NB-ARC PF00931.17 EMG50888.1 - 0.071 11.9 0.2 0.25 10.1 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 EMG50888.1 - 0.083 11.9 1.8 0.7 8.9 0.0 2.4 3 0 0 3 3 2 0 KaiC Viral_Hsp90 PF03225.9 EMG50888.1 - 0.1 10.8 0.2 0.15 10.3 0.1 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue ABC_tran PF00005.22 EMG50888.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.9 1 1 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.12 EMG50888.1 - 0.17 10.6 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 She9_MDM33 PF05546.6 EMG50889.1 - 2e-96 321.5 10.9 2e-96 321.5 7.6 2.2 2 0 0 2 2 2 1 She9 / Mdm33 family PLRV_ORF5 PF01690.12 EMG50889.1 - 0.007 15.5 1.6 0.007 15.5 1.1 2.4 2 1 0 2 2 2 1 Potato leaf roll virus readthrough protein PsbH PF00737.15 EMG50889.1 - 0.086 12.4 0.8 0.18 11.4 0.6 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Imm42 PF15601.1 EMG50889.1 - 0.1 12.0 2.4 0.25 10.7 0.1 2.5 1 1 0 2 2 2 0 Immunity protein 42 DUF2254 PF10011.4 EMG50889.1 - 1.2 7.4 5.3 0.56 8.6 1.8 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) ACR_tran PF00873.14 EMG50889.1 - 8.2 3.6 6.7 5.8 4.1 3.5 1.5 1 1 0 1 1 1 0 AcrB/AcrD/AcrF family PI-PLC-X PF00388.14 EMG50890.1 - 8.7e-19 67.3 0.0 1.3e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain CENP-Q PF13094.1 EMG50891.1 - 2.1e-19 70.0 0.8 2.1e-19 70.0 0.6 1.6 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit P53_tetramer PF07710.6 EMG50891.1 - 0.086 11.9 2.8 0.95 8.6 1.0 2.6 1 1 1 2 2 2 0 P53 tetramerisation motif DNA_ligase_A_M PF01068.16 EMG50892.1 - 3.5e-60 202.8 0.6 8e-60 201.6 0.4 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EMG50892.1 - 3.6e-27 95.3 0.1 7.1e-27 94.3 0.1 1.5 1 0 0 1 1 1 1 DNA ligase N terminus BRCT PF00533.21 EMG50892.1 - 3.6e-09 36.6 1.5 4.3e-08 33.1 0.2 2.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C PF04679.10 EMG50892.1 - 2.5e-06 27.7 0.0 5.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.14 EMG50892.1 - 3.8e-05 23.4 2.5 0.15 11.7 0.1 3.0 2 1 0 2 2 2 2 mRNA capping enzyme, catalytic domain GTP_EFTU PF00009.22 EMG50893.1 - 2.9e-63 212.7 0.4 4.1e-63 212.2 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EMG50893.1 - 1.2e-37 128.1 0.0 3.8e-37 126.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EMG50893.1 - 1.9e-21 75.7 0.0 4.3e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EMG50893.1 - 1.3e-13 50.5 0.0 3.6e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EMG50893.1 - 1.9e-12 47.1 1.4 5.3e-12 45.6 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMG50893.1 - 2.5e-05 24.1 0.2 5.8e-05 23.0 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase SUKH-4 PF14435.1 EMG50893.1 - 0.11 12.2 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 SUKH-4 immunity protein Ribonuc_red_lgC PF02867.10 EMG50894.1 - 7.5e-220 731.0 0.0 1e-219 730.6 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EMG50894.1 - 1.1e-21 76.3 0.0 2.9e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EMG50894.1 - 4.9e-16 58.9 3.0 6.1e-16 58.6 0.0 2.7 3 0 0 3 3 3 1 ATP cone domain NRDD PF13597.1 EMG50894.1 - 0.006 14.7 0.4 0.011 13.8 0.0 1.6 2 0 0 2 2 2 1 Anaerobic ribonucleoside-triphosphate reductase LCCL PF03815.14 EMG50895.1 - 2.8e-05 24.0 0.1 6.7e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 LCCL domain DDHD PF02862.12 EMG50896.1 - 2e-48 165.1 0.1 2e-48 165.1 0.1 3.9 2 2 0 2 2 2 1 DDHD domain Lipase_3 PF01764.20 EMG50896.1 - 0.049 13.2 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) DDHD PF02862.12 EMG50897.1 - 1.3e-54 185.4 0.0 7.1e-54 182.9 0.0 2.0 2 0 0 2 2 2 1 DDHD domain Lipase_3 PF01764.20 EMG50897.1 - 0.0095 15.5 0.0 0.028 14.0 0.0 1.8 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EMG50897.1 - 0.018 14.7 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EMG50897.1 - 0.021 14.3 0.0 0.082 12.4 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein DUF999 PF06198.6 EMG50897.1 - 0.069 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF999) DUF2305 PF10230.4 EMG50897.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EMG50897.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sugar_tr PF00083.19 EMG50898.1 - 7.8e-68 229.0 12.5 1.1e-67 228.5 8.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG50898.1 - 2.1e-26 92.5 18.8 3.8e-16 58.7 0.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Keratin_assoc PF09775.4 EMG50898.1 - 0.097 12.2 3.9 0.64 9.5 0.0 2.9 2 0 0 2 2 2 0 Keratinocyte-associated protein 2 Cu_amine_oxid PF01179.15 EMG50899.1 - 1.4e-157 524.6 0.1 1.8e-157 524.3 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain RNA_Me_trans PF04252.8 EMG50899.1 - 4e-44 150.3 0.0 6.8e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Cu_amine_oxidN3 PF02728.11 EMG50899.1 - 1.2e-24 86.2 0.0 3e-24 84.9 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EMG50899.1 - 1.6e-18 66.5 0.0 3.3e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF3810 PF12725.2 EMG50900.1 - 0.45 9.3 4.1 0.35 9.7 2.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) DUF2611 PF11022.3 EMG50901.1 - 7e-14 51.6 0.3 1.1e-13 51.0 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2611) PRP3 PF08572.5 EMG50902.1 - 1.1e-69 234.2 16.3 1.1e-69 234.2 11.3 1.5 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EMG50902.1 - 4.5e-32 110.4 1.5 4.5e-32 110.4 1.1 2.8 2 2 0 2 2 2 1 Protein of unknown function (DUF1115) HECT PF00632.20 EMG50903.1 - 1.2e-94 317.0 0.0 2.7e-94 315.8 0.0 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 EMG50903.1 - 8.8e-79 265.1 5.8 8.8e-79 265.1 4.0 2.5 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF913 PF06025.7 EMG50903.1 - 6.7e-48 163.3 0.5 6.7e-48 163.3 0.3 3.5 4 0 0 4 4 4 1 Domain of Unknown Function (DUF913) DUF4414 PF14377.1 EMG50903.1 - 4.2e-17 62.0 3.3 4.2e-17 62.0 2.3 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4414) SSP160 PF06933.6 EMG50903.1 - 2.4 6.0 13.6 4 5.3 9.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 AIF_C PF14721.1 EMG50903.1 - 8.6 6.6 9.5 3.9 7.7 0.5 2.8 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term zf-H2C2_2 PF13465.1 EMG50904.1 - 0.02 15.1 2.4 0.02 15.1 1.6 4.8 3 2 1 4 4 4 0 Zinc-finger double domain zf-C2H2 PF00096.21 EMG50904.1 - 0.022 15.0 3.3 0.022 15.0 2.3 5.4 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-CHCC PF10276.4 EMG50904.1 - 0.091 12.6 0.1 0.091 12.6 0.1 2.4 3 0 0 3 3 3 0 Zinc-finger domain zf-C2H2_jaz PF12171.3 EMG50904.1 - 0.15 12.2 0.1 0.15 12.2 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EMG50904.1 - 0.86 10.0 25.0 0.31 11.4 2.1 5.3 5 0 0 5 5 5 0 C2H2-type zinc finger ELO PF01151.13 EMG50905.1 - 1.7e-59 201.1 27.2 2e-59 200.8 18.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CNH PF00780.17 EMG50906.1 - 1.3e-72 244.5 0.8 1.7e-72 244.1 0.0 1.6 2 0 0 2 2 2 1 CNH domain RhoGEF PF00621.15 EMG50906.1 - 6.8e-40 136.8 1.3 1.9e-39 135.4 0.9 1.8 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EMG50906.1 - 1.7e-25 89.5 0.3 1.7e-25 89.5 0.2 3.5 3 1 1 4 4 4 1 Pleckstrin homology domain DEP PF00610.16 EMG50906.1 - 5.6e-12 45.2 0.1 1.5e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_10 PF15411.1 EMG50906.1 - 0.14 12.2 2.7 0.31 11.2 0.1 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain His_Phos_1 PF00300.17 EMG50907.1 - 1e-39 136.2 0.0 1.3e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PITH PF06201.8 EMG50908.1 - 4.1e-41 140.2 0.7 5.4e-41 139.8 0.5 1.1 1 0 0 1 1 1 1 PITH domain Aa_trans PF01490.13 EMG50909.1 - 1.7e-94 316.6 31.2 1.9e-94 316.4 21.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EMG50909.1 - 0.0077 14.8 34.9 0.05 12.1 24.2 2.0 1 1 0 1 1 1 1 Amino acid permease Nucleoporin_FG PF13634.1 EMG50910.1 - 5.6e-24 84.5 138.9 1.2e-09 38.3 23.5 5.2 1 1 3 4 4 4 4 Nucleoporin FG repeat region Nsp1_C PF05064.8 EMG50911.1 - 7e-36 122.4 8.1 7e-36 122.4 5.6 2.7 2 1 0 3 3 3 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 EMG50911.1 - 1.4e-17 63.9 56.8 1.8e-12 47.4 12.2 3.2 2 1 1 3 3 3 2 Nucleoporin FG repeat region DUF745 PF05335.8 EMG50911.1 - 0.2 11.1 7.0 0.26 10.8 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF745) WEMBL PF05701.6 EMG50911.1 - 0.61 8.4 16.9 5.9 5.2 11.7 2.0 1 1 0 1 1 1 0 Weak chloroplast movement under blue light HATPase_c PF02518.21 EMG50912.1 - 9.1e-26 89.7 0.2 2.3e-25 88.4 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMG50912.1 - 2.7e-18 65.9 0.1 1e-17 64.1 0.0 2.1 1 0 0 1 1 1 1 Response regulator receiver domain Pkinase PF00069.20 EMG50912.1 - 2e-16 59.9 0.0 4.1e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain GAF_3 PF13492.1 EMG50912.1 - 8.5e-15 55.0 0.0 2.7e-14 53.3 0.0 1.9 2 0 0 2 2 2 1 GAF domain HisKA PF00512.20 EMG50912.1 - 1.3e-14 53.9 0.1 4.5e-14 52.1 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 EMG50912.1 - 2.7e-10 40.5 0.0 5.1e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain GAF_2 PF13185.1 EMG50912.1 - 4.7e-08 33.6 0.0 4.9e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 GAF domain GAF PF01590.21 EMG50912.1 - 5.9e-08 32.9 0.0 1.7e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 GAF domain Snf7 PF03357.16 EMG50913.1 - 3.1e-28 98.2 17.1 3.9e-28 97.9 11.8 1.1 1 0 0 1 1 1 1 Snf7 ALAD PF00490.16 EMG50914.1 - 4e-116 387.4 0.0 4.9e-116 387.1 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase PQ-loop PF04193.9 EMG50915.1 - 2.8e-14 52.3 4.5 2.6e-09 36.4 0.1 3.6 2 1 0 2 2 2 2 PQ loop repeat Pkinase PF00069.20 EMG50916.1 - 1.9e-72 243.5 0.0 2.4e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG50916.1 - 4.3e-31 107.9 0.0 6.8e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMG50916.1 - 1.6e-05 24.0 0.0 0.0013 17.7 0.0 2.6 2 1 0 3 3 3 1 Kinase-like Kdo PF06293.9 EMG50916.1 - 2.7e-05 23.3 0.1 0.00013 21.1 0.1 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMG50916.1 - 0.00072 19.3 0.1 0.0026 17.5 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EMG50916.1 - 0.14 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Dus PF01207.12 EMG50917.1 - 5.4e-47 160.1 0.0 5e-46 156.9 0.0 2.0 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EMG50917.1 - 0.2 11.3 3.0 3 7.6 0.1 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) IL6 PF00489.12 EMG50918.1 - 0.013 15.0 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family Vps39_1 PF10366.4 EMG50920.1 - 4.6e-35 119.8 5.1 1.1e-34 118.7 0.6 3.3 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EMG50920.1 - 5.2e-18 65.2 0.1 1.7e-17 63.5 0.1 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 BBS2_N PF14781.1 EMG50920.1 - 0.064 12.8 1.0 2 8.0 0.1 3.2 1 1 2 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal SEEEED PF14797.1 EMG50920.1 - 1.3 9.1 12.9 0.017 15.2 3.7 1.8 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex Utp21 PF04192.7 EMG50921.1 - 1.1e-75 253.8 1.4 1.8e-75 253.0 1.0 1.4 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EMG50921.1 - 1.9e-18 65.5 10.6 1.5e-09 37.3 0.1 8.5 9 1 0 9 9 9 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EMG50921.1 - 1.8e-08 34.1 0.0 3.9e-06 26.5 0.0 3.2 2 2 1 3 3 3 1 PQQ-like domain Cytochrom_D1 PF02239.11 EMG50921.1 - 0.0035 15.7 0.0 0.01 14.1 0.0 1.7 2 0 0 2 2 2 1 Cytochrome D1 heme domain Nrap PF03813.9 EMG50922.1 - 0 1255.6 9.4 0 1255.2 6.5 1.2 1 0 0 1 1 1 1 Nrap protein DUF2890 PF11081.3 EMG50922.1 - 2.1 8.3 15.1 3.9 7.4 10.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Prenyltrans_2 PF13249.1 EMG50923.1 - 2.6e-26 92.2 0.0 1.6e-13 51.0 0.0 4.5 2 1 2 4 4 4 4 Prenyltransferase-like Prenyltrans PF00432.16 EMG50923.1 - 9e-25 85.9 8.5 8.5e-08 31.6 0.4 4.6 4 1 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 EMG50923.1 - 2.5e-24 85.3 0.0 8.1e-14 51.5 0.0 5.8 3 3 3 6 6 6 4 Prenyltransferase-like Pec_lyase PF09492.5 EMG50923.1 - 3.3e-05 23.2 0.7 0.44 9.6 0.0 4.7 3 1 2 5 5 5 2 Pectic acid lyase A2M_comp PF07678.9 EMG50923.1 - 0.067 12.4 0.0 0.4 9.8 0.0 2.2 2 0 0 2 2 2 0 A-macroglobulin complement component Grp1_Fun34_YaaH PF01184.14 EMG50924.1 - 1.6e-54 184.3 25.4 2.2e-54 183.9 17.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family BRAP2 PF07576.7 EMG50925.1 - 5.7e-28 96.6 1.3 1.5e-27 95.3 0.1 2.1 2 0 0 2 2 2 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EMG50925.1 - 9.3e-20 70.5 3.7 2.2e-19 69.3 2.6 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EMG50925.1 - 7.8e-09 35.2 10.9 7.8e-09 35.2 7.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EMG50925.1 - 3.7e-05 23.3 8.1 3.7e-05 23.3 5.6 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMG50925.1 - 4.1e-05 23.1 10.0 0.00013 21.5 7.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMG50925.1 - 5.4e-05 22.7 7.7 5.4e-05 22.7 5.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMG50925.1 - 0.00012 21.9 9.8 0.00012 21.9 6.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMG50925.1 - 0.00056 19.9 5.2 0.00056 19.9 3.6 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EMG50925.1 - 0.0041 16.7 4.7 0.013 15.2 1.9 2.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 EMG50925.1 - 0.0062 16.3 5.4 0.016 15.0 3.8 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TMF_DNA_bd PF12329.3 EMG50925.1 - 0.018 14.8 6.9 0.018 14.8 4.8 3.9 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding TerY-C PF15616.1 EMG50925.1 - 0.22 11.4 13.4 0.033 14.0 2.6 2.8 1 1 1 2 2 2 0 TerY-C metal binding domain Reo_sigmaC PF04582.7 EMG50925.1 - 0.32 10.1 4.4 0.55 9.3 3.1 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein ATG16 PF08614.6 EMG50925.1 - 9.7 5.9 33.1 0.28 11.0 14.8 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) zf-RING_4 PF14570.1 EMG50925.1 - 10 5.8 17.4 0.05 13.1 5.4 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Pribosyl_synth PF14572.1 EMG50926.1 - 3.5e-42 144.2 2.5 4.3e-36 124.3 1.2 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EMG50926.1 - 2.6e-38 130.3 0.8 1.2e-37 128.1 0.0 2.2 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EMG50926.1 - 4.3e-11 42.6 1.7 1e-10 41.4 1.2 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EMG50926.1 - 0.0073 15.5 0.2 0.012 14.7 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.3 EMG50926.1 - 0.075 12.7 1.5 0.16 11.6 1.1 1.5 1 0 0 1 1 1 0 Chlorosome envelope protein C TAFII55_N PF04658.8 EMG50927.1 - 2.1e-43 147.6 0.3 2.1e-43 147.6 0.2 2.5 2 1 1 3 3 3 1 TAFII55 protein conserved region P5-ATPase PF12409.3 EMG50928.1 - 6.3e-37 126.0 0.2 2.5e-36 124.1 0.1 2.1 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 EMG50928.1 - 1.5e-28 100.3 0.1 3.4e-28 99.1 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EMG50928.1 - 1.2e-27 96.4 0.1 2.2e-27 95.5 0.1 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EMG50928.1 - 1.5e-16 61.4 0.1 1.5e-15 58.1 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMG50928.1 - 2.5e-07 30.5 0.0 7.2e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EMG50928.1 - 5.8e-05 22.4 0.0 0.00018 20.8 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EMG50928.1 - 0.00029 20.5 0.3 0.72 9.3 0.0 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase GATA PF00320.22 EMG50929.1 - 4.3e-14 51.5 5.5 9.9e-14 50.4 3.8 1.6 1 0 0 1 1 1 1 GATA zinc finger S1 PF00575.18 EMG50930.1 - 3.8e-63 209.5 48.5 5.4e-15 55.2 0.4 13.5 13 0 0 13 13 13 10 S1 RNA binding domain Suf PF05843.9 EMG50930.1 - 1.4e-05 24.9 2.4 1.4e-05 24.9 1.7 4.7 3 1 1 4 4 4 1 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EMG50930.1 - 0.00021 21.5 0.0 5.6 7.3 0.0 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMG50930.1 - 0.0017 18.8 0.0 20 6.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat FAM176 PF14851.1 EMG50930.1 - 0.0019 17.8 0.5 0.0019 17.8 0.4 5.3 3 1 1 4 4 4 1 FAM176 family PPR PF01535.15 EMG50930.1 - 0.027 14.4 0.3 0.52 10.4 0.2 2.8 2 0 0 2 2 2 0 PPR repeat TPR_16 PF13432.1 EMG50930.1 - 0.1 13.3 0.0 58 4.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Globin PF00042.17 EMG50931.1 - 0.0051 17.1 0.1 0.0087 16.4 0.1 1.4 1 0 0 1 1 1 1 Globin zf-C3HC4_2 PF13923.1 EMG50932.1 - 0.001 19.0 1.9 0.002 18.1 0.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMG50932.1 - 0.0037 16.9 2.4 0.0037 16.9 1.7 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EMG50932.1 - 0.0045 16.7 0.4 0.011 15.5 0.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMG50932.1 - 0.0071 15.9 2.6 0.0071 15.9 1.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMG50932.1 - 0.011 15.5 0.2 0.035 13.9 0.1 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Fer2_3 PF13085.1 EMG50932.1 - 0.069 12.9 0.9 0.17 11.6 0.2 2.0 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain zf-C3HC4_3 PF13920.1 EMG50932.1 - 0.1 12.2 3.7 0.061 13.0 0.6 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Opi1 PF08618.5 EMG50933.1 - 1.9e-17 63.3 20.8 1.9e-08 33.6 1.6 3.8 2 1 2 4 4 4 3 Transcription factor Opi1 Cation_efflux PF01545.16 EMG50934.1 - 1.6e-75 253.8 0.0 3.4e-75 252.7 0.0 1.6 1 1 0 1 1 1 1 Cation efflux family Dehydrin PF00257.14 EMG50934.1 - 0.032 14.5 7.9 0.056 13.7 5.5 1.3 1 0 0 1 1 1 0 Dehydrin Zip PF02535.17 EMG50934.1 - 0.073 12.0 8.7 0.22 10.5 6.0 1.8 1 1 0 1 1 1 0 ZIP Zinc transporter SNARE PF05739.14 EMG50935.1 - 3.7e-17 61.7 1.6 9.5e-17 60.4 1.1 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 EMG50935.1 - 1.2e-05 25.3 0.2 1.2e-05 25.3 0.1 2.6 2 1 0 2 2 2 1 Syntaxin DUF3357 PF11837.3 EMG50935.1 - 0.031 14.1 0.0 0.082 12.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Septin PF00735.13 EMG50937.1 - 1.4e-76 257.1 2.0 2.5e-76 256.3 1.4 1.4 1 0 0 1 1 1 1 Septin Miro PF08477.8 EMG50937.1 - 0.00053 20.4 0.0 0.0022 18.4 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMG50937.1 - 0.0009 19.1 0.1 0.0031 17.4 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMG50937.1 - 0.0021 17.8 2.5 0.035 13.9 0.0 2.5 2 0 0 2 2 2 1 Dynamin family Lipoprotein_X PF03305.8 EMG50937.1 - 0.0086 15.4 3.9 0.016 14.6 2.7 1.3 1 0 0 1 1 1 1 Mycoplasma MG185/MG260 protein AKNA PF12443.3 EMG50937.1 - 0.014 15.3 2.8 0.035 14.1 2.0 1.6 1 0 0 1 1 1 0 AT-hook-containing transcription factor FeoB_N PF02421.13 EMG50937.1 - 0.019 14.2 0.1 0.047 12.9 0.0 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 EMG50937.1 - 0.025 14.0 0.2 0.19 11.1 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Nsp1_C PF05064.8 EMG50937.1 - 0.081 12.5 7.7 0.25 10.9 4.7 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF4407 PF14362.1 EMG50937.1 - 0.21 10.5 1.1 0.3 9.9 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Dzip-like_N PF13815.1 EMG50937.1 - 3.9 7.3 9.6 0.31 10.8 1.4 2.4 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF3589 PF12141.3 EMG50938.1 - 1.6e-15 56.3 0.0 1.8e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3589) Zip PF02535.17 EMG50939.1 - 4.6e-29 101.4 23.0 6.4e-24 84.5 15.9 2.2 1 1 0 1 1 1 1 ZIP Zinc transporter PNRC PF15365.1 EMG50940.1 - 0.00039 20.3 0.4 0.00039 20.3 0.3 3.7 4 1 0 4 4 4 1 Proline-rich nuclear receptor coactivator DUF3560 PF12083.3 EMG50940.1 - 0.29 11.2 4.1 0.46 10.5 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) PIN_4 PF13638.1 EMG50941.1 - 1.4e-06 28.4 0.0 8.3e-05 22.7 0.0 2.4 1 1 0 1 1 1 1 PIN domain SNF2_N PF00176.18 EMG50942.1 - 1.3e-79 267.1 1.0 1.3e-79 267.1 0.7 2.8 3 0 0 3 3 3 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EMG50942.1 - 5.8e-21 74.2 0.4 1.9e-20 72.5 0.3 1.9 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 EMG50942.1 - 4.7e-17 61.6 3.7 8.9e-17 60.7 0.0 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SnAC PF14619.1 EMG50942.1 - 8.4e-16 57.9 10.2 8.4e-16 57.9 7.0 4.1 3 2 1 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex RrnaAD PF00398.15 EMG50943.1 - 1.7e-26 92.8 0.0 2.2e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase GidB PF02527.10 EMG50943.1 - 0.012 14.8 0.0 0.023 13.8 0.0 1.5 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_32 PF13679.1 EMG50943.1 - 0.17 11.6 0.1 0.55 9.9 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain Pex16 PF08610.5 EMG50944.1 - 0.0029 16.6 0.5 0.0043 16.1 0.3 1.1 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) PAT1 PF09770.4 EMG50944.1 - 3 5.9 12.7 3.8 5.6 8.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 EMG50945.1 - 5.3e-69 233.0 8.4 5.3e-69 233.0 5.9 4.1 3 2 1 4 4 4 2 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EMG50945.1 - 0.00067 19.9 0.1 0.021 15.1 0.0 3.1 3 1 1 4 4 4 1 Tetratricopeptide repeat Tom37_C PF11801.3 EMG50946.1 - 6.2e-58 195.3 5.5 7.9e-58 195.0 3.8 1.1 1 0 0 1 1 1 1 Tom37 C-terminal domain Sec16_N PF12935.2 EMG50946.1 - 0.024 14.5 0.6 0.037 13.9 0.4 1.2 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 N-terminus DUF3740 PF12548.3 EMG50946.1 - 0.046 14.0 0.2 0.046 14.0 0.2 1.7 2 0 0 2 2 2 0 Sulfatase protein DUF4448 PF14610.1 EMG50947.1 - 6.1e-60 201.9 0.2 1.2e-59 200.9 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Grp1_Fun34_YaaH PF01184.14 EMG50948.1 - 5.6e-60 202.2 21.4 6.9e-60 201.9 14.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Flavi_NS4A PF01350.12 EMG50948.1 - 0.64 9.5 2.5 1.1 8.7 0.1 2.1 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A DAHP_synth_1 PF00793.15 EMG50949.1 - 6.2e-104 346.4 0.0 7.1e-104 346.2 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family UCH PF00443.24 EMG50952.1 - 1.7e-46 158.5 1.5 3.5e-46 157.5 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMG50952.1 - 3.9e-21 75.7 0.6 4.6e-20 72.2 0.0 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EMG50952.1 - 7.6e-21 73.9 7.1 2.3e-20 72.4 4.9 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 EMG50952.1 - 9.9e-19 66.6 0.1 6.2e-08 32.2 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain SUR7 PF06687.7 EMG50954.1 - 8.8e-19 67.9 24.2 8.8e-19 67.9 16.8 1.8 2 0 0 2 2 2 1 SUR7/PalI family PIP5K PF01504.13 EMG50955.1 - 6.2e-64 215.5 6.4 1.8e-63 214.0 4.4 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EMG50955.1 - 5.5e-23 81.3 1.6 1e-22 80.4 1.1 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EMG50955.1 - 8.2e-17 60.8 8.7 8.2e-17 60.8 6.0 2.5 2 0 0 2 2 2 1 FYVE zinc finger GPP34 PF05719.6 EMG50956.1 - 1.7e-58 198.1 0.0 2.1e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Glyco_hydro_18 PF00704.23 EMG50957.1 - 8.3e-83 278.6 2.6 9.5e-83 278.4 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.8 EMG50957.1 - 0.018 14.1 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 DUF3142 PF11340.3 EMG50957.1 - 0.083 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) LRR_4 PF12799.2 EMG50958.1 - 0.00075 19.0 9.9 1 9.0 0.1 4.3 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) Leader_CPA1 PF08252.6 EMG50958.1 - 0.029 13.6 0.7 0.086 12.1 0.5 1.8 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide LRR_6 PF13516.1 EMG50958.1 - 2.7 8.3 11.4 44 4.6 0.4 5.8 7 0 0 7 7 7 0 Leucine Rich repeat PLA2_B PF01735.13 EMG50959.1 - 9.7e-167 555.0 17.5 5.4e-166 552.5 12.1 1.8 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Pox_L3_FP4 PF03339.9 EMG50959.1 - 0.045 12.2 0.1 0.073 11.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus L3/FP4 protein DUF2977 PF11192.3 EMG50960.1 - 0.024 14.4 3.1 0.024 14.4 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2977) Arrestin_C PF02752.17 EMG50961.1 - 1.2e-21 77.2 0.0 2e-19 70.0 0.0 2.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EMG50961.1 - 8.6e-10 38.6 0.1 2.1e-06 27.6 0.0 2.6 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EMG50961.1 - 0.091 12.2 0.0 0.24 10.8 0.0 1.7 1 0 0 1 1 1 0 Arrestin_N terminal like Cyclin_N PF00134.18 EMG50962.1 - 1.7e-42 143.9 0.8 3.5e-40 136.5 0.1 2.7 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMG50962.1 - 6.5e-32 109.9 0.0 2.4e-31 108.0 0.0 2.0 1 0 0 1 1 1 1 Cyclin, C-terminal domain TFIIA PF03153.8 EMG50962.1 - 0.017 15.0 8.9 0.021 14.7 6.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPARC_Ca_bdg PF10591.4 EMG50962.1 - 0.53 10.3 4.1 2.5 8.1 2.9 2.2 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3439 PF11921.3 EMG50962.1 - 1.5 8.5 8.4 3 7.6 5.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) BRCT PF00533.21 EMG50963.1 - 2.5e-26 91.6 9.8 1.9e-07 31.1 0.0 6.7 6 1 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EMG50963.1 - 1.5e-18 66.3 3.1 5.5e-13 48.5 0.2 5.0 5 1 0 5 5 5 2 twin BRCT domain TFIIA PF03153.8 EMG50963.1 - 4.6 7.0 10.4 7.2 6.3 7.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ENTH PF01417.15 EMG50964.1 - 3.7e-43 146.3 0.1 3.7e-43 146.3 0.1 1.6 2 0 0 2 2 2 1 ENTH domain UIM PF02809.15 EMG50964.1 - 0.0025 17.2 4.4 0.3 10.7 0.3 3.1 2 0 0 2 2 2 2 Ubiquitin interaction motif VHS PF00790.14 EMG50964.1 - 0.047 13.3 0.1 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 VHS domain PAT1 PF09770.4 EMG50964.1 - 7 4.7 70.9 0.014 13.6 36.3 2.1 1 1 1 2 2 2 0 Topoisomerase II-associated protein PAT1 HD PF01966.17 EMG50965.1 - 7.9e-06 25.8 0.0 1.1e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 HD domain Pribosyltran PF00156.22 EMG50966.1 - 1.3e-17 63.6 0.0 1.8e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EMG50966.1 - 0.029 13.5 0.0 0.038 13.1 0.0 1.1 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase ADIP PF11559.3 EMG50967.1 - 0.021 14.7 3.6 0.021 14.7 2.5 3.4 2 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 EMG50967.1 - 0.024 14.1 16.3 0.022 14.2 1.9 3.4 3 1 0 3 3 3 0 Septum formation initiator FadA PF09403.5 EMG50967.1 - 0.1 12.6 20.7 0.029 14.3 6.3 2.7 1 1 1 2 2 2 0 Adhesion protein FadA bZIP_1 PF00170.16 EMG50967.1 - 0.23 11.4 18.9 0.049 13.6 2.4 4.2 1 1 3 4 4 4 0 bZIP transcription factor TSC22 PF01166.13 EMG50967.1 - 9.1 6.3 11.9 0.29 11.1 0.9 3.4 3 1 0 3 3 3 0 TSC-22/dip/bun family IncA PF04156.9 EMG50967.1 - 9.8 5.7 24.9 59 3.1 16.2 2.8 2 1 0 2 2 2 0 IncA protein WD40 PF00400.27 EMG50969.1 - 4.5e-15 54.8 2.9 0.00068 19.4 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat CDC45 PF02724.9 EMG50969.1 - 0.0036 15.4 8.0 0.0051 14.9 5.5 1.1 1 0 0 1 1 1 1 CDC45-like protein eIF2A PF08662.6 EMG50969.1 - 0.0046 16.7 1.3 0.18 11.4 0.2 3.4 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nop14 PF04147.7 EMG50969.1 - 0.24 9.2 13.0 0.34 8.7 9.0 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.1 EMG50969.1 - 4.9 6.8 7.6 3.3 7.3 4.0 1.7 2 0 0 2 2 2 0 FAM176 family RXT2_N PF08595.6 EMG50969.1 - 6.7 6.4 10.5 4.6 7.0 5.8 1.8 1 1 0 1 1 1 0 RXT2-like, N-terminal Ssl1 PF04056.9 EMG50970.1 - 2.6e-63 213.1 0.0 3.7e-63 212.6 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EMG50970.1 - 4.2e-21 74.7 14.0 1.1e-20 73.4 6.1 2.5 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EMG50970.1 - 9.5e-09 35.5 0.0 1.8e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EMG50970.1 - 2.8e-05 23.9 0.2 4.4e-05 23.2 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain DZR PF12773.2 EMG50970.1 - 9.7e-05 22.1 12.1 0.012 15.3 0.1 3.3 2 1 0 2 2 2 2 Double zinc ribbon DUF2296 PF10058.4 EMG50970.1 - 0.19 11.4 4.8 5.6 6.7 0.0 3.5 2 1 1 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) CpXC PF14353.1 EMG50970.1 - 1 9.3 8.4 6.9 6.6 1.8 2.9 2 1 0 2 2 2 0 CpXC protein IBR PF01485.16 EMG50970.1 - 1.4 8.8 17.1 14 5.6 11.8 2.7 1 1 0 1 1 1 0 IBR domain zf-AN1 PF01428.11 EMG50970.1 - 1.8 8.4 15.8 0.92 9.4 0.4 2.8 2 1 0 2 2 2 0 AN1-like Zinc finger Spt5-NGN PF03439.8 EMG50971.1 - 5.7e-23 80.4 0.0 1.3e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 EMG50971.1 - 7.8e-20 71.2 16.9 7.8e-20 71.2 11.7 3.6 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 EMG50971.1 - 1.2e-13 50.1 12.2 8e-06 25.3 1.1 5.1 5 0 0 5 5 5 3 KOW motif NusG PF02357.14 EMG50971.1 - 0.00087 19.4 0.3 0.083 13.1 0.0 3.1 3 0 0 3 3 3 1 Transcription termination factor nusG Daxx PF03344.10 EMG50971.1 - 0.58 8.5 34.3 0.95 7.8 23.8 1.3 1 0 0 1 1 1 0 Daxx Family Med13_C PF06333.7 EMG50972.1 - 1.3e-117 392.9 11.8 1.8e-67 227.7 0.3 3.8 4 0 0 4 4 4 2 Mediator complex subunit 13 C-terminal COX6A PF02046.10 EMG50973.1 - 5.6e-44 148.7 2.3 6.3e-44 148.6 1.6 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa RNase_T PF00929.19 EMG50974.1 - 1.7e-29 103.2 0.0 2.3e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Exonuclease MinE PF03776.9 EMG50974.1 - 0.023 14.1 0.0 0.072 12.6 0.0 1.8 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE DUF3589 PF12141.3 EMG50975.1 - 3e-156 520.5 1.4 3.5e-156 520.3 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3589) DUF3589 PF12141.3 EMG50976.1 - 4.2e-171 569.5 13.6 5.1e-171 569.2 9.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3589) LNS2 PF08235.8 EMG50977.1 - 1.5e-70 235.7 0.0 3.9e-70 234.4 0.0 1.7 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) TauD PF02668.11 EMG50977.1 - 1.9e-52 178.4 0.1 3.2e-52 177.7 0.0 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Lipin_N PF04571.9 EMG50977.1 - 1e-37 128.1 0.0 2.8e-37 126.7 0.0 1.8 1 0 0 1 1 1 1 lipin, N-terminal conserved region Hydrolase_6 PF13344.1 EMG50977.1 - 0.08 12.8 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase CN_hydrolase PF00795.17 EMG50978.1 - 1.5e-26 92.8 0.0 2.3e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EMG50978.1 - 2.2e-22 79.1 0.0 7.7e-22 77.3 0.0 1.8 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 EMG50978.1 - 0.082 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase Abhydrolase_6 PF12697.2 EMG50979.1 - 3.3e-19 69.6 0.0 4.4e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMG50979.1 - 2.2e-14 53.4 0.0 2.7e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMG50979.1 - 4.5e-13 49.2 0.0 8.7e-13 48.3 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EMG50979.1 - 1.1e-07 31.6 0.0 2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 EMG50979.1 - 0.00019 21.0 0.0 0.00034 20.2 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EMG50979.1 - 0.00042 19.9 0.1 0.00061 19.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Pax7 PF12360.3 EMG50979.1 - 0.005 17.0 0.1 3.6 7.9 0.0 2.5 2 0 0 2 2 2 2 Paired box protein 7 Ser_hydrolase PF06821.8 EMG50979.1 - 0.027 14.0 0.0 0.26 10.8 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase Ndr PF03096.9 EMG50979.1 - 0.027 12.9 0.0 0.034 12.6 0.0 1.2 1 0 0 1 1 1 0 Ndr family Thioesterase PF00975.15 EMG50979.1 - 0.036 14.2 0.0 0.087 13.0 0.0 1.6 1 1 0 1 1 1 0 Thioesterase domain DUF2305 PF10230.4 EMG50979.1 - 0.078 12.3 0.1 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_3 PF07859.8 EMG50979.1 - 0.086 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF915 PF06028.6 EMG50979.1 - 0.098 11.7 0.0 0.26 10.3 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydro_lipase PF04083.11 EMG50979.1 - 0.11 11.8 0.0 0.45 9.8 0.0 1.9 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Rep_2 PF01719.12 EMG50980.1 - 0.011 15.2 0.9 0.016 14.7 0.5 1.3 1 1 0 1 1 1 0 Plasmid replication protein DUF2150 PF09920.4 EMG50980.1 - 0.048 13.2 0.1 0.076 12.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) COX5B PF01215.14 EMG50981.1 - 2.1e-42 144.0 0.0 2.4e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Ribosomal_S26e PF01283.14 EMG50982.1 - 4.7e-52 175.0 9.1 5.6e-52 174.8 6.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e mono-CXXC PF15626.1 EMG50982.1 - 0.022 14.7 1.0 0.07 13.0 0.7 1.9 1 0 0 1 1 1 0 single CXXC unit Fer4_7 PF12838.2 EMG50982.1 - 0.036 14.4 0.6 0.21 11.9 0.2 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 EMG50982.1 - 0.13 12.0 0.5 0.13 12.0 0.3 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain FYVE PF01363.16 EMG50983.1 - 2.8e-15 55.9 5.0 6.2e-15 54.8 3.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.11 EMG50983.1 - 4.9 7.1 13.4 0.88 9.4 6.6 1.8 2 0 0 2 2 2 0 AN1-like Zinc finger STT3 PF02516.9 EMG50984.1 - 5.4e-142 474.1 47.6 1.2e-138 463.1 30.8 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit MT-A70 PF05063.9 EMG50985.1 - 7.9e-52 175.3 1.0 3.3e-51 173.3 0.1 2.0 2 0 0 2 2 2 1 MT-A70 SH3_1 PF00018.23 EMG50986.1 - 1.3e-36 123.6 13.8 3.5e-14 51.9 0.4 4.3 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.7 EMG50986.1 - 3.3e-36 122.7 0.0 6e-36 121.9 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 EMG50986.1 - 1.4e-34 117.4 7.6 4.7e-11 42.1 0.1 4.5 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 EMG50986.1 - 4.2e-26 90.1 0.3 2e-08 33.5 0.1 4.9 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.6 EMG50986.1 - 0.57 10.4 4.9 17 5.6 0.1 3.5 3 0 0 3 3 3 0 Bacterial SH3 domain Pox_F17 PF04767.7 EMG50986.1 - 3.4 7.9 0.0 3.4 7.9 0.0 3.1 3 0 0 3 3 3 0 DNA-binding 11 kDa phosphoprotein Spc24 PF08286.6 EMG50987.1 - 3.2e-23 81.6 9.7 9.9e-23 80.0 1.9 2.3 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Snapin_Pallidin PF14712.1 EMG50987.1 - 1.6e-05 25.1 12.6 0.0011 19.2 0.7 3.3 1 1 1 3 3 3 2 Snapin/Pallidin DUF4618 PF15397.1 EMG50987.1 - 0.00026 20.4 9.0 0.00063 19.1 6.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4618) Lipoprotein_20 PF13942.1 EMG50987.1 - 0.041 13.4 9.3 0.12 11.8 0.7 2.3 2 0 0 2 2 2 0 YfhG lipoprotein DUF3552 PF12072.3 EMG50987.1 - 0.15 11.2 7.6 0.12 11.5 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) SlyX PF04102.7 EMG50987.1 - 0.28 11.5 9.0 0.64 10.4 0.7 2.8 2 0 0 2 2 2 0 SlyX Atg14 PF10186.4 EMG50987.1 - 0.55 9.1 7.0 1.2 8.0 4.9 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 MerR-DNA-bind PF09278.6 EMG50987.1 - 0.63 10.4 4.2 10 6.5 0.0 3.6 3 2 0 3 3 3 0 MerR, DNA binding Prefoldin PF02996.12 EMG50987.1 - 0.94 9.1 7.9 4.2 7.0 0.4 2.4 2 0 0 2 2 2 0 Prefoldin subunit Rootletin PF15035.1 EMG50987.1 - 0.98 9.3 9.2 3.3 7.6 6.1 1.8 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Baculo_PEP_C PF04513.7 EMG50987.1 - 1.3 8.8 17.3 0.71 9.6 5.5 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliD_N PF02465.13 EMG50987.1 - 1.8 8.9 6.2 1.4 9.3 0.3 2.7 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF848 PF05852.6 EMG50987.1 - 2.4 8.0 9.3 1.9 8.3 2.3 2.5 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) EMP24_GP25L PF01105.19 EMG50987.1 - 2.9 7.5 11.0 3.2 7.4 1.8 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF948 PF06103.6 EMG50987.1 - 4.1 7.3 13.4 1.4 8.7 0.3 3.4 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF4200 PF13863.1 EMG50987.1 - 6.2 6.7 10.0 10 6.1 1.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF2730 PF10805.3 EMG50987.1 - 6.7 6.5 8.4 3.7 7.3 0.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) Cmc1 PF08583.5 EMG50988.1 - 2.1e-07 30.6 4.3 2.1e-07 30.6 3.0 1.8 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like AICARFT_IMPCHas PF01808.13 EMG50988.1 - 0.3 10.1 2.6 0.34 9.9 1.8 1.0 1 0 0 1 1 1 0 AICARFT/IMPCHase bienzyme DASH_Hsk3 PF08227.6 EMG50989.1 - 3.7e-15 55.8 0.9 5e-15 55.3 0.6 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like FlhD PF05247.8 EMG50989.1 - 0.053 13.5 0.1 0.065 13.2 0.1 1.2 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhD) AKNA PF12443.3 EMG50989.1 - 0.056 13.4 0.1 0.069 13.1 0.1 1.2 1 0 0 1 1 1 0 AT-hook-containing transcription factor ImcF-related_N PF14331.1 EMG50989.1 - 0.1 11.5 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 ImcF-related N-terminal domain Hap4_Hap_bind PF10297.4 EMG50990.1 - 2.1e-07 30.5 10.4 5e-07 29.3 7.2 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 Tir_receptor_C PF07489.6 EMG50990.1 - 7.4 6.2 21.0 0.66 9.6 3.9 3.0 3 0 0 3 3 3 0 Translocated intimin receptor (Tir) C-terminus Sdh_cyt PF01127.17 EMG50991.1 - 3e-26 91.6 1.3 3.8e-26 91.2 0.9 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ecl1 PF12855.2 EMG50992.1 - 2.9e-16 58.4 10.4 5.6e-16 57.5 7.2 1.5 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 EMG50992.1 - 0.048 13.5 6.2 0.048 13.5 4.3 2.4 2 1 0 2 2 2 0 MYND finger SDA1 PF05285.7 EMG50992.1 - 0.084 12.1 0.9 0.1 11.8 0.6 1.1 1 0 0 1 1 1 0 SDA1 BAF1_ABF1 PF04684.8 EMG50992.1 - 0.1 11.3 16.6 0.12 11.2 11.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Shisa PF13908.1 EMG50992.1 - 0.11 12.6 5.7 0.15 12.2 3.9 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator GTSE1_N PF15259.1 EMG50992.1 - 1.4 8.8 6.3 1.7 8.5 3.7 1.6 1 1 1 2 2 2 0 G-2 and S-phase expressed 1 Zip PF02535.17 EMG50992.1 - 1.4 7.8 5.8 1.7 7.5 4.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter HSP70 PF00012.15 EMG50993.1 - 3.3e-264 877.3 14.3 3.8e-264 877.1 9.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMG50993.1 - 2.3e-19 69.1 1.8 1.5e-18 66.4 0.4 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 EMG50993.1 - 0.00043 19.2 1.0 0.00088 18.2 0.5 1.5 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 EMG50993.1 - 0.01 14.9 4.7 0.096 11.7 0.2 3.2 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.1 EMG50993.1 - 0.23 11.3 9.4 2.8 7.8 1.0 3.5 2 2 0 2 2 2 0 Cell division protein FtsA cNMP_binding PF00027.24 EMG50994.1 - 4.7e-45 151.3 0.1 3.7e-23 81.1 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 EMG50994.1 - 8.9e-11 41.0 0.9 3.4e-10 39.1 0.1 2.4 3 0 0 3 3 3 1 Regulatory subunit of type II PKA R-subunit ABC2_membrane_3 PF12698.2 EMG50994.1 - 1.5 7.7 3.4 0.29 10.1 0.1 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein Erg28 PF03694.8 EMG50995.1 - 4.7e-44 148.9 0.3 5.7e-44 148.6 0.2 1.1 1 0 0 1 1 1 1 Erg28 like protein Vps54 PF07928.7 EMG50996.1 - 1.1e-15 57.9 4.6 1.1e-15 57.9 3.2 3.8 3 1 0 3 3 3 1 Vps54-like protein DUF2450 PF10475.4 EMG50996.1 - 1.4e-07 30.7 10.2 6.2e-05 22.0 1.9 2.5 2 0 0 2 2 2 2 Protein of unknown function N-terminal domain (DUF2450) IF-2B PF01008.12 EMG50997.1 - 1.1e-47 162.3 0.1 2.6e-47 161.1 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family Pex2_Pex12 PF04757.9 EMG50998.1 - 2.5e-60 203.7 15.4 3.4e-60 203.3 10.7 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EMG50998.1 - 0.00083 19.1 0.5 0.0016 18.3 0.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EMG50998.1 - 0.0023 17.9 0.4 0.0058 16.6 0.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PBP1_TM PF14812.1 EMG50998.1 - 0.11 12.8 2.6 0.35 11.1 1.8 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.6 EMG50998.1 - 0.82 9.4 7.8 0.28 10.9 3.2 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 EMG50998.1 - 6.9 6.1 12.0 12 5.3 8.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin Not3 PF04065.10 EMG50999.1 - 9.5e-42 142.8 30.7 9.7e-40 136.2 21.3 2.4 1 1 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EMG50999.1 - 0.0037 17.1 1.0 0.0037 17.1 0.7 4.5 5 2 0 5 5 5 2 NOT2 / NOT3 / NOT5 family Lge1 PF11488.3 EMG50999.1 - 0.13 12.5 0.2 0.13 12.5 0.1 3.1 3 1 0 3 3 3 0 Transcriptional regulatory protein LGE1 DUF3596 PF12167.3 EMG50999.1 - 1.5 8.3 6.6 1.6 8.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3596) Cep57_MT_bd PF06657.8 EMG50999.1 - 3.5 7.6 10.9 0.17 11.8 2.5 2.6 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DUF1752 PF08550.5 EMG51000.1 - 2.7e-11 42.8 3.1 5.3e-11 41.9 2.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF3661 PF12400.3 EMG51001.1 - 1.8e-42 144.4 9.2 1.8e-42 144.4 6.4 1.8 2 0 0 2 2 2 1 Vaculolar membrane protein Pkinase PF00069.20 EMG51002.1 - 2.1e-45 154.9 0.2 6.3e-45 153.3 0.2 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG51002.1 - 2.5e-22 79.2 0.4 3.3e-19 68.9 0.3 2.9 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EMG51002.1 - 7.8e-06 25.6 2.3 1.1e-05 25.0 0.1 2.3 2 1 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EMG51002.1 - 1.9e-05 24.5 0.1 3.9e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EMG51002.1 - 0.0017 17.7 1.5 0.0044 16.3 1.0 1.7 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EMG51002.1 - 0.039 13.0 2.3 0.071 12.1 0.9 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PLD_C PF12357.3 EMG51002.1 - 0.072 12.6 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 Phospholipase D C terminal Metallophos PF00149.23 EMG51003.1 - 1.5e-09 37.5 0.0 7e-09 35.3 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMG51003.1 - 0.0011 18.8 0.0 0.0021 17.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Mpp10 PF04006.7 EMG51003.1 - 0.34 9.2 29.2 0.48 8.7 20.2 1.1 1 0 0 1 1 1 0 Mpp10 protein Vfa1 PF08432.5 EMG51003.1 - 0.57 10.1 22.9 1.2 9.0 15.8 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GAGA_bind PF06217.7 EMG51003.1 - 1.7 8.5 11.7 3.6 7.4 8.1 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family Pkinase PF00069.20 EMG51004.1 - 1.1e-64 218.0 0.0 1.8e-64 217.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMG51004.1 - 1.3e-48 165.3 0.0 2e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EMG51004.1 - 6.1e-35 119.3 0.1 1.2e-34 118.3 0.1 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 EMG51004.1 - 4.6e-09 35.9 0.1 1.1e-08 34.7 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMG51004.1 - 1.4e-08 34.7 0.1 4.3e-08 33.2 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 EMG51004.1 - 4.5e-06 25.8 0.0 8.1e-05 21.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF1104 PF06518.6 EMG51005.1 - 0.59 10.3 4.1 1.2 9.3 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1104) Ferric_reduct PF01794.14 EMG51006.1 - 6.2e-15 55.3 6.5 6.2e-15 55.3 4.5 2.7 2 1 1 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EMG51006.1 - 5.8e-08 32.7 0.0 5.4e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMG51006.1 - 1.4e-07 31.2 0.2 3e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EMG51006.1 - 0.0025 18.3 0.0 0.0084 16.6 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF2244 PF10003.4 EMG51006.1 - 3.9 6.8 7.6 0.41 10.0 1.3 2.1 1 1 1 2 2 2 0 Integral membrane protein (DUF2244) HLH PF00010.21 EMG51007.1 - 7.7e-08 31.9 1.4 7.7e-08 31.9 1.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain TEBP_beta PF07404.6 EMG51007.1 - 0.042 12.9 0.7 0.049 12.7 0.5 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) DUF837 PF05769.6 EMG51007.1 - 0.057 12.9 2.6 0.069 12.6 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF837) DUF4662 PF15578.1 EMG51007.1 - 0.19 11.3 1.8 0.21 11.1 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) DUF3713 PF12506.3 EMG51007.1 - 1.5 8.9 9.4 2.2 8.3 4.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3713) ATP_bind_4 PF01902.12 EMG51008.1 - 3.7e-41 140.9 0.0 8.6e-41 139.6 0.0 1.6 1 1 0 1 1 1 1 ATP-binding region Ribonuc_L-PSP PF01042.16 EMG51008.1 - 3e-19 68.9 0.0 1.3e-10 41.0 0.0 2.3 2 0 0 2 2 2 2 Endoribonuclease L-PSP QueC PF06508.8 EMG51008.1 - 0.098 11.9 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC S4 PF01479.20 EMG51009.1 - 1.5e-13 49.9 0.8 4.9e-13 48.2 0.2 1.9 2 0 0 2 2 2 1 S4 domain Ribosomal_L21e PF01157.13 EMG51010.1 - 6.7e-42 141.3 6.6 1.8e-41 139.9 3.8 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e LRS4 PF10422.4 EMG51010.1 - 0.00044 19.6 0.0 0.00053 19.4 0.0 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 CASP_C PF08172.7 EMG51011.1 - 4.1e-81 271.6 8.2 4.1e-81 271.6 5.7 3.8 3 1 0 3 3 3 1 CASP C terminal NPV_P10 PF05531.7 EMG51011.1 - 4.8e-05 23.5 1.1 4.8e-05 23.5 0.8 6.3 6 2 0 6 6 6 1 Nucleopolyhedrovirus P10 protein PglZ PF08665.7 EMG51011.1 - 0.042 13.5 0.1 0.042 13.5 0.1 3.4 3 1 1 4 4 4 0 PglZ domain IncA PF04156.9 EMG51011.1 - 0.33 10.5 72.0 0.034 13.7 3.0 5.9 3 1 3 6 6 6 0 IncA protein TPR_MLP1_2 PF07926.7 EMG51011.1 - 1.1 8.9 69.6 0.012 15.4 5.4 6.0 3 3 1 4 4 4 0 TPR/MLP1/MLP2-like protein DUF2935 PF11155.3 EMG51011.1 - 1.6 8.8 32.4 0.37 10.8 0.6 5.5 3 1 1 4 4 4 0 Domain of unknown function (DUF2935) Hemerythrin PF01814.18 EMG51011.1 - 2.2 8.4 7.9 3.5 7.7 0.2 4.0 3 1 1 4 4 4 0 Hemerythrin HHE cation binding domain Reo_sigmaC PF04582.7 EMG51011.1 - 4.5 6.3 22.6 0.057 12.5 0.4 3.5 3 1 1 4 4 4 0 Reovirus sigma C capsid protein Ada_Zn_binding PF02805.11 EMG51013.1 - 8.4e-12 44.5 0.4 1.4e-11 43.7 0.3 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada zf-FPG_IleRS PF06827.9 EMG51013.1 - 0.0028 17.2 1.7 0.0045 16.5 0.0 2.2 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS HTH_AraC PF00165.18 EMG51013.1 - 0.0042 16.8 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 EMG51013.1 - 0.015 15.4 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain CN_hydrolase PF00795.17 EMG51016.1 - 1.3e-17 63.7 0.0 2.4e-17 62.9 0.0 1.5 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase LicD PF04991.8 EMG51017.1 - 1.4e-45 155.9 0.9 1.4e-45 155.9 0.6 3.4 3 1 0 3 3 3 1 LicD family DUF3589 PF12141.3 EMG51018.1 - 2.6e-167 557.0 0.4 3.3e-167 556.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3589) DUF3688 PF12461.3 EMG51018.1 - 6.6 7.1 7.8 0.44 10.9 0.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3688) Pyr_redox_3 PF13738.1 EMG51019.1 - 4.3e-20 72.6 0.0 8.9e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMG51019.1 - 3.3e-14 51.9 0.7 8.5e-11 40.7 0.2 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EMG51019.1 - 2.6e-11 43.0 0.1 4.9e-09 35.5 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EMG51019.1 - 2.1e-07 30.8 0.0 4.6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMG51019.1 - 0.00013 21.8 0.0 0.0013 18.5 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMG51019.1 - 0.00046 20.1 0.0 0.0016 18.3 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EMG51019.1 - 0.0023 18.0 0.0 0.62 10.1 0.0 3.3 3 1 1 4 4 4 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 EMG51019.1 - 0.0064 15.4 0.1 0.11 11.3 0.1 2.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMG51019.1 - 0.035 12.9 0.0 0.062 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EMG51019.1 - 0.041 12.9 0.1 0.15 11.0 0.0 2.0 3 0 0 3 3 3 0 Thi4 family Aminotran_3 PF00202.16 EMG51021.1 - 1.4e-93 313.4 0.0 1.6e-93 313.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EMG51021.1 - 0.011 14.7 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II ADH_zinc_N_2 PF13602.1 EMG51024.1 - 1.1e-19 71.5 0.0 2.6e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EMG51024.1 - 1.1e-08 34.6 0.0 3e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMG51024.1 - 0.00085 19.0 0.0 0.0027 17.4 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Polysacc_synt_2 PF02719.10 EMG51024.1 - 0.018 13.9 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EMG51024.1 - 0.038 14.1 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 EMG51024.1 - 0.081 11.9 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TMV_coat PF00721.16 EMG51025.1 - 0.14 12.0 1.7 0.15 11.9 1.2 1.0 1 0 0 1 1 1 0 Virus coat protein (TMV like) TcdA_TcdB_pore PF12920.2 EMG51025.1 - 0.19 9.6 3.4 0.2 9.5 2.4 1.0 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain LicD PF04991.8 EMG51026.1 - 2.8e-51 174.5 4.3 2.8e-51 174.5 3.0 3.3 3 2 0 3 3 3 1 LicD family Mgr1 PF08602.5 EMG51028.1 - 9.2e-97 324.2 0.8 3.4e-50 171.0 0.9 2.1 1 1 1 2 2 2 2 Mgr1-like, i-AAA protease complex subunit SR-25 PF10500.4 EMG51028.1 - 5.1 6.5 12.8 8.4 5.7 8.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein COX5A PF02284.11 EMG51029.1 - 6.2e-41 138.7 1.0 8.6e-41 138.2 0.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va AMP-binding_C_2 PF14535.1 EMG51029.1 - 0.11 12.6 0.2 0.25 11.4 0.1 1.6 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain bZIP_1 PF00170.16 EMG51031.1 - 2.2e-08 33.9 13.8 2.6e-05 24.0 9.6 2.2 1 1 0 1 1 1 1 bZIP transcription factor Phage_GP20 PF06810.6 EMG51031.1 - 0.032 13.6 3.4 0.045 13.1 2.4 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 ADIP PF11559.3 EMG51031.1 - 0.15 11.9 7.2 0.21 11.5 5.0 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Clathrin_lg_ch PF01086.12 EMG51031.1 - 0.15 11.9 5.8 0.19 11.6 4.0 1.1 1 0 0 1 1 1 0 Clathrin light chain Phlebovirus_NSM PF07246.6 EMG51031.1 - 0.21 10.7 2.6 0.26 10.4 1.8 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M HAUS6_N PF14661.1 EMG51031.1 - 0.36 10.1 5.2 0.48 9.7 3.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF972 PF06156.8 EMG51031.1 - 0.55 10.5 3.5 0.58 10.5 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 EMG51031.1 - 0.79 9.5 14.7 2.3 8.0 1.5 2.2 1 1 1 2 2 2 0 Basic region leucine zipper PBP PF01161.15 EMG51032.1 - 3.7e-12 46.3 0.1 7.2e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF688 PF05097.7 EMG51032.1 - 0.0022 17.0 0.7 0.0022 17.0 0.5 2.0 2 1 1 3 3 3 1 Protein of unknown function (DUF688) Nucleoplasmin PF03066.10 EMG51032.1 - 0.27 10.7 7.0 0.52 9.8 4.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin MIF4G PF02854.14 EMG51033.1 - 1.6e-20 73.4 43.1 1.5e-10 40.8 2.2 4.4 4 1 0 4 4 4 3 MIF4G domain Upf2 PF04050.9 EMG51033.1 - 4e-13 49.4 43.6 1.6e-11 44.2 30.2 2.7 1 1 0 1 1 1 1 Up-frameshift suppressor 2 Nop14 PF04147.7 EMG51033.1 - 8.4e-06 24.0 34.0 2.7e-05 22.3 23.6 1.9 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 EMG51033.1 - 0.037 13.3 36.0 0.079 12.2 25.0 1.6 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 EMG51033.1 - 0.47 8.8 35.7 0.8 8.1 24.8 1.3 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EMG51033.1 - 2.7 5.9 36.5 0.87 7.5 23.0 1.8 2 0 0 2 2 2 0 CDC45-like protein IMS PF00817.15 EMG51034.1 - 4e-43 146.7 0.0 6.8e-43 146.0 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EMG51034.1 - 2.3e-09 37.2 0.1 4.2e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EMG51034.1 - 2.4e-05 24.1 0.0 5.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif Sec23_trunk PF04811.10 EMG51035.1 - 5.7e-42 143.7 0.0 1.3e-41 142.6 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EMG51035.1 - 2.7e-24 84.5 0.5 6.6e-24 83.3 0.4 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EMG51035.1 - 3e-18 66.0 0.0 3e-18 66.0 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EMG51035.1 - 5.3e-15 54.6 6.9 9.9e-15 53.8 4.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger DUF1676 PF07898.8 EMG51035.1 - 0.005 17.1 0.2 0.013 15.7 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1676) UNC45-central PF11701.3 EMG51036.1 - 7.9e-32 110.0 3.8 7.9e-32 110.0 2.6 2.8 3 1 0 3 3 3 1 Myosin-binding striated muscle assembly central Arm PF00514.18 EMG51036.1 - 0.89 9.4 4.6 2.8 7.9 0.5 3.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat ING PF12998.2 EMG51037.1 - 7.7e-16 58.2 4.8 1.2e-15 57.6 3.4 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EMG51037.1 - 7.2e-10 38.4 8.4 1.4e-09 37.5 5.8 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EMG51037.1 - 0.025 14.7 0.3 0.066 13.3 0.2 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.1 EMG51037.1 - 0.046 13.0 2.9 0.093 12.0 2.0 1.6 1 0 0 1 1 1 0 PHD-finger GAPT PF11770.3 EMG51037.1 - 0.068 12.8 0.1 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) DDHD PF02862.12 EMG51037.1 - 0.089 12.5 0.8 0.18 11.5 0.1 1.7 2 0 0 2 2 2 0 DDHD domain zf-RING-like PF08746.6 EMG51037.1 - 0.25 11.3 2.9 0.46 10.5 2.0 1.4 1 0 0 1 1 1 0 RING-like domain PhnA_Zn_Ribbon PF08274.7 EMG51037.1 - 0.27 11.0 2.8 2.6 7.9 0.2 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-C4_Topoisom PF01396.14 EMG51037.1 - 3.7 7.1 7.6 5.3 6.6 0.8 2.4 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger PalH PF08733.5 EMG51038.1 - 2.1e-82 276.7 18.9 3.4e-82 276.0 13.1 1.2 1 0 0 1 1 1 1 PalH/RIM21 DUF3295 PF11702.3 EMG51038.1 - 2.8 6.8 13.1 3.7 6.4 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) AAA_2 PF07724.9 EMG51039.1 - 1.6e-51 174.6 0.4 3e-50 170.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EMG51039.1 - 3.5e-23 81.3 0.5 1.4e-22 79.3 0.3 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EMG51039.1 - 7.5e-21 74.7 0.1 5.5e-11 42.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMG51039.1 - 7.2e-16 58.1 0.0 3.3e-10 39.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMG51039.1 - 3e-14 53.4 0.0 0.00057 19.9 0.0 4.3 2 2 2 4 4 4 3 AAA ATPase domain AAA_22 PF13401.1 EMG51039.1 - 3.2e-10 40.2 0.8 5.4e-05 23.3 0.0 3.8 2 2 2 4 4 4 2 AAA domain Sigma54_activat PF00158.21 EMG51039.1 - 1.1e-08 34.6 0.1 1.3e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 EMG51039.1 - 6.3e-08 32.5 0.9 0.011 15.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 EMG51039.1 - 7.6e-06 25.4 0.1 0.073 12.4 0.0 2.9 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_28 PF13521.1 EMG51039.1 - 2.9e-05 24.0 0.4 1.6 8.6 0.0 4.0 4 1 0 4 4 3 2 AAA domain TrwB_AAD_bind PF10412.4 EMG51039.1 - 3.6e-05 22.5 0.4 0.2 10.2 0.1 2.7 2 1 0 3 3 3 2 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 EMG51039.1 - 3.9e-05 23.3 0.1 0.23 11.1 0.0 3.0 3 0 0 3 3 2 2 NACHT domain RNA_helicase PF00910.17 EMG51039.1 - 5.7e-05 23.2 0.5 0.23 11.6 0.0 3.5 3 1 0 3 3 3 1 RNA helicase MobB PF03205.9 EMG51039.1 - 5.8e-05 22.8 0.0 0.12 12.1 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EMG51039.1 - 6.6e-05 22.5 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 Part of AAA domain AAA_30 PF13604.1 EMG51039.1 - 9.5e-05 22.0 0.0 0.21 11.1 0.0 3.3 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EMG51039.1 - 0.00019 21.1 12.2 0.035 13.7 0.4 4.8 4 2 0 4 4 3 1 Archaeal ATPase MMR_HSR1 PF01926.18 EMG51039.1 - 0.00051 19.9 0.1 0.036 14.0 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase T2SE PF00437.15 EMG51039.1 - 0.00072 18.5 0.7 0.1 11.4 0.1 3.0 2 1 1 3 3 3 1 Type II/IV secretion system protein DUF815 PF05673.8 EMG51039.1 - 0.0015 17.5 0.8 0.39 9.6 0.1 3.4 2 2 0 2 2 2 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EMG51039.1 - 0.0017 19.2 10.4 0.09 13.6 0.2 4.2 2 2 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMG51039.1 - 0.0017 17.4 3.0 0.016 14.3 0.0 3.4 4 1 0 4 4 3 1 Zeta toxin ResIII PF04851.10 EMG51039.1 - 0.0018 18.0 7.0 1.7 8.4 0.0 4.3 3 1 1 4 4 4 2 Type III restriction enzyme, res subunit PhoH PF02562.11 EMG51039.1 - 0.0021 17.3 0.0 2.1 7.5 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein SRP54 PF00448.17 EMG51039.1 - 0.0024 17.3 0.1 0.38 10.1 0.0 3.0 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain UPF0079 PF02367.12 EMG51039.1 - 0.0051 16.4 0.0 2 8.0 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 EMG51039.1 - 0.0054 15.9 0.1 1.7 7.7 0.0 2.7 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EMG51039.1 - 0.0071 16.6 2.8 0.39 11.0 0.0 3.6 3 1 0 3 3 3 1 ABC transporter PduV-EutP PF10662.4 EMG51039.1 - 0.008 15.6 0.3 0.7 9.3 0.0 2.9 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation DUF853 PF05872.7 EMG51039.1 - 0.0095 14.3 0.2 0.12 10.6 0.1 2.4 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF853) DUF87 PF01935.12 EMG51039.1 - 0.01 15.6 5.9 1.2 8.9 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_24 PF13479.1 EMG51039.1 - 0.014 14.9 0.2 0.92 9.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EMG51039.1 - 0.019 14.3 0.0 3.7 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EMG51039.1 - 0.027 14.3 0.5 3 7.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain Torsin PF06309.6 EMG51039.1 - 0.029 14.2 0.0 1.2 8.9 0.0 2.6 2 0 0 2 2 2 0 Torsin Malic_M PF03949.10 EMG51039.1 - 0.038 13.5 0.1 0.088 12.3 0.1 1.5 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain CbiA PF01656.18 EMG51039.1 - 0.044 13.1 0.1 0.25 10.7 0.0 2.3 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.1 EMG51039.1 - 0.057 13.7 15.8 0.41 10.9 0.1 4.2 4 1 0 4 4 2 0 AAA domain AAA_10 PF12846.2 EMG51039.1 - 0.057 12.8 2.1 3.5 6.9 0.2 3.2 2 2 0 2 2 2 0 AAA-like domain PDE6_gamma PF04868.7 EMG51039.1 - 0.099 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit AAA_29 PF13555.1 EMG51039.1 - 0.1 12.1 0.0 10 5.7 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain EF-hand_4 PF12763.2 EMG51040.1 - 1.4e-24 85.8 0.0 6.6e-12 45.0 0.0 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.6 EMG51040.1 - 3.5e-05 23.7 223.5 0.0034 17.4 32.8 9.9 4 2 4 8 8 8 6 Domain of unknown function (DUF1720) WH2 PF02205.15 EMG51040.1 - 0.00011 21.7 0.1 0.00031 20.2 0.1 1.8 1 0 0 1 1 1 1 WH2 motif EF-hand_7 PF13499.1 EMG51040.1 - 0.0003 20.8 0.0 0.0039 17.2 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 EMG51040.1 - 0.0015 18.0 0.5 0.38 10.4 0.0 3.8 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.27 EMG51040.1 - 0.0022 17.1 0.0 0.23 10.8 0.0 2.8 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 EMG51040.1 - 0.16 11.9 0.1 3.3 7.8 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain Phos_pyr_kin PF08543.7 EMG51041.1 - 2e-68 230.2 0.0 3.4e-68 229.5 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EMG51041.1 - 3.9e-46 157.4 0.4 5.4e-46 157.0 0.3 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 EMG51041.1 - 0.0019 17.4 0.1 0.0051 15.9 0.0 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 EMG51041.1 - 0.027 13.6 0.1 0.14 11.2 0.1 2.0 1 1 0 1 1 1 0 Hydroxyethylthiazole kinase family DUF4087 PF13316.1 EMG51041.1 - 0.088 13.0 0.0 4.9 7.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4087) A_deaminase PF00962.17 EMG51042.1 - 1.2e-109 366.2 0.1 1.6e-109 365.8 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Calpain_inhib PF00748.14 EMG51043.1 - 0.084 13.2 0.7 3 8.2 0.0 2.6 1 1 1 2 2 2 0 Calpain inhibitor Rgp1 PF08737.5 EMG51044.1 - 5.1e-101 338.7 4.7 5.1e-101 338.7 3.3 2.7 2 1 1 3 3 3 1 Rgp1 Mem_trans PF03547.13 EMG51044.1 - 1.9e-54 184.4 1.7 9.8e-54 182.1 1.2 1.9 1 1 0 1 1 1 1 Membrane transport protein Arrestin_C PF02752.17 EMG51044.1 - 6.1e-06 26.3 0.4 6.1e-06 26.3 0.2 3.1 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain ADH_zinc_N_2 PF13602.1 EMG51046.1 - 1.1e-20 74.7 0.0 2.9e-20 73.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EMG51046.1 - 3.9e-12 45.8 0.0 7.6e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMG51046.1 - 6.8e-06 25.8 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Shikimate_DH PF01488.15 EMG51046.1 - 0.0031 17.6 0.1 0.0055 16.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 EMG51046.1 - 0.016 14.3 0.1 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Acetyltransf_1 PF00583.19 EMG51047.1 - 0.14 12.2 0.2 17 5.5 0.0 2.2 1 1 1 2 2 2 0 Acetyltransferase (GNAT) family LSM PF01423.17 EMG51048.1 - 6.3e-16 57.6 0.4 7.2e-16 57.5 0.3 1.0 1 0 0 1 1 1 1 LSM domain tRNA-synt_1e PF01406.14 EMG51049.1 - 0.0089 15.1 1.1 0.017 14.2 0.8 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain ENTH PF01417.15 EMG51050.1 - 2e-45 153.6 0.1 3.4e-45 152.9 0.1 1.4 1 0 0 1 1 1 1 ENTH domain DUF605 PF04652.11 EMG51050.1 - 0.00038 19.9 20.5 0.00046 19.6 14.2 1.2 1 0 0 1 1 1 1 Vta1 like ANTH PF07651.11 EMG51050.1 - 0.001 17.8 0.0 0.0015 17.2 0.0 1.3 1 0 0 1 1 1 1 ANTH domain DUF572 PF04502.8 EMG51050.1 - 0.87 8.7 11.4 1.9 7.6 7.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF572) SSP160 PF06933.6 EMG51050.1 - 5.5 4.8 17.1 14 3.4 11.8 1.6 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SAC3_GANP PF03399.11 EMG51051.1 - 7.2e-66 221.6 0.4 7.2e-66 221.6 0.3 2.3 3 0 0 3 3 3 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family SAC3 PF12209.3 EMG51051.1 - 4.7e-17 61.8 1.1 4.7e-17 61.8 0.7 2.5 2 0 0 2 2 2 1 Leucine permease transcriptional regulator helical domain Methyltransf_16 PF10294.4 EMG51052.1 - 6.1e-20 71.3 0.2 9e-20 70.8 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EMG51052.1 - 0.03 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Semialdhyde_dhC PF02774.13 EMG51053.1 - 7e-43 146.6 0.0 1.1e-42 145.9 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EMG51053.1 - 5.2e-31 107.4 0.0 8.9e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 EMG51053.1 - 0.00057 20.4 0.0 0.0014 19.1 0.0 1.7 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Saccharop_dh PF03435.13 EMG51053.1 - 0.0015 17.5 0.2 0.0053 15.7 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase DapB_N PF01113.15 EMG51053.1 - 0.02 14.7 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus SSrecog PF03531.9 EMG51054.1 - 3.3e-77 258.7 0.6 8.4e-77 257.4 0.4 1.7 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EMG51054.1 - 6e-30 103.0 0.0 1.4e-27 95.4 0.0 3.4 3 0 0 3 3 3 1 Histone chaperone Rttp106-like CDC45 PF02724.9 EMG51054.1 - 0.14 10.1 11.0 0.2 9.6 7.6 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIIC_delta PF12657.2 EMG51055.1 - 9.9e-06 25.3 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 EMG51055.1 - 0.027 14.3 0.0 0.084 12.7 0.0 1.9 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex Helicase_C_2 PF13307.1 EMG51056.1 - 2.4e-56 190.2 0.1 7.4e-56 188.6 0.0 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EMG51056.1 - 3.6e-46 156.7 1.9 7.7e-46 155.6 0.7 2.1 2 0 0 2 2 2 1 DEAD_2 Phage_RpbA PF10789.4 EMG51056.1 - 0.0045 16.8 0.5 0.014 15.2 0.3 1.8 1 0 0 1 1 1 1 Phage RNA polymerase binding, RpbA NTS_2 PF15448.1 EMG51056.1 - 0.076 13.3 3.8 0.27 11.5 0.5 2.9 2 0 0 2 2 2 0 N-terminal segments of P. falciparum erythrocyte membrane protein Nic96 PF04097.9 EMG51057.1 - 3.1e-210 699.4 8.7 5e-210 698.7 6.0 1.3 1 0 0 1 1 1 1 Nup93/Nic96 DUF2802 PF10975.3 EMG51057.1 - 0.23 11.2 4.0 0.42 10.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) AA_permease_2 PF13520.1 EMG51058.1 - 3.3e-46 157.6 51.3 4.1e-46 157.3 35.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMG51058.1 - 3e-23 81.9 46.3 4.2e-23 81.4 32.1 1.1 1 0 0 1 1 1 1 Amino acid permease SPC25 PF06703.6 EMG51058.1 - 0.92 9.0 3.2 1.1 8.8 0.4 2.4 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) SIR2 PF02146.12 EMG51059.1 - 3.8e-61 205.8 0.0 5.3e-61 205.4 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EMG51059.1 - 0.0026 17.3 0.1 0.019 14.5 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF592) SSP160 PF06933.6 EMG51059.1 - 0.0098 13.9 0.6 0.013 13.5 0.4 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 TPP_enzyme_M PF00205.17 EMG51059.1 - 0.038 13.7 0.0 0.36 10.5 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Dicty_REP PF05086.7 EMG51059.1 - 0.31 8.7 3.5 0.54 7.9 0.3 2.1 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein PALP PF00291.20 EMG51060.1 - 1.5e-57 195.1 0.0 1.7e-57 195.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme YjeF_N PF03853.10 EMG51060.1 - 0.04 13.5 0.0 0.089 12.3 0.0 1.6 1 0 0 1 1 1 0 YjeF-related protein N-terminus Fungal_trans PF04082.13 EMG51061.1 - 9.3e-31 106.6 0.1 9.3e-31 106.6 0.1 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG51061.1 - 9.1e-09 35.0 10.6 1.6e-08 34.3 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMG51062.1 - 1.5e-17 63.3 2.5 5.1e-17 61.5 1.8 2.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG51062.1 - 1.5e-06 27.9 10.9 3.3e-06 26.9 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_76 PF03663.9 EMG51063.1 - 2.4e-146 487.8 25.4 2.9e-146 487.5 17.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 PX PF00787.19 EMG51064.1 - 1.4e-16 60.2 1.8 1.4e-16 60.2 1.2 3.1 4 0 0 4 4 4 1 PX domain Vps5 PF09325.5 EMG51064.1 - 0.0011 18.2 11.2 0.0014 17.9 2.3 2.3 2 0 0 2 2 2 2 Vps5 C terminal like DUF972 PF06156.8 EMG51064.1 - 0.0013 19.0 2.2 0.0013 19.0 1.6 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF972) DUF2400 PF09674.5 EMG51064.1 - 0.012 15.3 1.9 0.012 15.3 1.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2400) YPEB PF14620.1 EMG51064.1 - 0.073 12.0 8.1 0.45 9.4 0.5 2.3 2 0 0 2 2 2 0 YpeB sporulation DUF1664 PF07889.7 EMG51064.1 - 0.078 12.7 5.2 2.1 8.1 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Nup54 PF13874.1 EMG51064.1 - 0.1 12.2 4.3 0.19 11.3 0.7 2.5 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 GrpE PF01025.14 EMG51064.1 - 1 8.9 9.6 1.5 8.3 1.1 2.8 2 0 0 2 2 2 0 GrpE IncA PF04156.9 EMG51064.1 - 2 7.9 17.0 2.2 7.8 0.8 2.8 2 1 0 2 2 2 0 IncA protein Lung_7-TM_R PF06814.8 EMG51065.1 - 1.8e-55 187.9 20.0 3.4e-55 187.0 13.9 1.4 1 1 0 1 1 1 1 Lung seven transmembrane receptor RNA_pol_Rpb2_1 PF04563.10 EMG51065.1 - 0.058 12.3 0.0 0.09 11.6 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase beta subunit DUF1625 PF07787.7 EMG51065.1 - 5.3 6.2 12.3 0.078 12.2 3.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1625) PCI PF01399.22 EMG51066.1 - 1.3e-10 41.5 1.2 1.3e-10 41.5 0.9 2.4 2 0 0 2 2 2 1 PCI domain TPR_19 PF14559.1 EMG51066.1 - 0.0061 16.8 0.3 0.57 10.5 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat PX PF00787.19 EMG51067.1 - 1.2e-18 66.9 4.9 3.3e-17 62.3 0.7 2.5 2 0 0 2 2 2 2 PX domain BLOC1_2 PF10046.4 EMG51067.1 - 0.38 10.9 12.9 0.37 10.9 0.4 3.8 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mannosyl_trans3 PF11051.3 EMG51068.1 - 3e-89 298.9 0.0 5e-89 298.2 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative Acyl_transf_2 PF02273.10 EMG51068.1 - 0.032 13.2 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 Acyl transferase HAD_2 PF13419.1 EMG51070.1 - 1e-17 64.9 0.0 2.9e-17 63.4 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMG51070.1 - 0.0016 18.0 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like PWI PF01480.12 EMG51071.1 - 1e-05 25.5 3.5 1.3e-05 25.1 1.0 2.3 2 0 0 2 2 2 1 PWI domain NRDE-2 PF08424.5 EMG51072.1 - 7.8e-05 21.7 10.0 0.003 16.5 0.1 4.0 2 2 1 3 3 3 3 NRDE-2, necessary for RNA interference Mad3_BUB1_I PF08311.7 EMG51072.1 - 1.3 8.8 16.1 0.3 10.8 2.9 4.2 2 2 1 3 3 3 0 Mad3/BUB1 homology region 1 C1_1 PF00130.17 EMG51073.1 - 0.3 10.8 2.9 0.16 11.6 0.2 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) LRR_6 PF13516.1 EMG51073.1 - 0.92 9.7 20.5 2.7 8.3 0.0 7.2 8 0 0 8 8 8 0 Leucine Rich repeat UBA PF00627.26 EMG51074.1 - 1.2e-20 72.7 5.6 2.7e-12 46.1 0.1 3.0 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.18 EMG51074.1 - 5.9e-19 67.2 1.1 6.2e-18 63.9 1.0 2.5 3 0 0 3 3 3 1 Ubiquitin family XPC-binding PF09280.6 EMG51074.1 - 2.2e-16 59.0 6.9 4.5e-16 58.0 4.8 1.5 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.3 EMG51074.1 - 4.3e-09 35.9 1.5 1e-08 34.7 1.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EMG51074.1 - 0.00047 20.0 0.1 0.0011 18.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EMG51074.1 - 0.0045 17.1 0.1 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Macoilin PF09726.4 EMG51074.1 - 0.15 10.3 10.1 0.19 9.9 7.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Ashwin PF15323.1 EMG51074.1 - 0.41 10.6 10.1 0.28 11.1 5.1 1.9 2 0 0 2 2 2 0 Developmental protein DUF1455 PF07306.6 EMG51074.1 - 2.2 8.3 5.2 0.35 10.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1455) DUF3336 PF11815.3 EMG51075.1 - 5.3e-46 155.7 4.5 1e-45 154.8 3.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EMG51075.1 - 1.2e-17 64.5 0.0 2.2e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Pept_tRNA_hydro PF01195.14 EMG51076.1 - 1.6e-24 86.4 0.0 2e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase DUF2341 PF10102.4 EMG51076.1 - 0.09 12.9 0.1 0.2 11.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2341) Lin-8 PF03353.10 EMG51077.1 - 0.016 14.4 6.2 0.034 13.4 4.3 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF605 PF04652.11 EMG51077.1 - 2.6 7.3 16.6 3.2 7.0 11.5 1.2 1 0 0 1 1 1 0 Vta1 like RNA_pol_I_A49 PF06870.7 EMG51079.1 - 3.3e-128 427.5 2.1 3.7e-128 427.3 1.4 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Sugar_tr PF00083.19 EMG51080.1 - 2.3e-141 471.4 28.4 2.7e-141 471.2 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG51080.1 - 3.6e-27 94.9 33.8 4.5e-27 94.7 16.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMG51080.1 - 0.00016 20.0 3.0 0.00031 19.0 2.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LMF1 PF06762.9 EMG51080.1 - 0.066 11.9 0.2 0.13 11.0 0.2 1.5 1 0 0 1 1 1 0 Lipase maturation factor FA_desaturase PF00487.19 EMG51080.1 - 4.6 6.6 15.1 0.057 12.8 2.8 2.7 2 1 0 2 2 2 0 Fatty acid desaturase Ribosomal_L16 PF00252.13 EMG51081.1 - 1.9e-34 118.2 0.3 2.6e-34 117.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e zf-CSL PF05207.8 EMG51082.1 - 6.7e-17 60.7 2.2 9e-17 60.3 1.5 1.2 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EMG51082.1 - 1.4e-14 53.5 0.1 2.4e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Lar_restr_allev PF14354.1 EMG51082.1 - 0.034 14.4 0.8 0.051 13.8 0.6 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar Sugar_tr PF00083.19 EMG51083.1 - 1.5e-147 491.8 35.2 1.8e-147 491.5 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMG51083.1 - 1.3e-26 93.1 35.7 9.2e-23 80.5 16.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily 6PGD PF00393.14 EMG51083.1 - 0.076 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 6-phosphogluconate dehydrogenase, C-terminal domain HTH_29 PF13551.1 EMG51084.1 - 3.3e-06 27.2 0.0 4.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix Sigma70_r4_2 PF08281.7 EMG51084.1 - 0.00089 18.6 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.1 EMG51084.1 - 0.0045 16.6 0.0 0.0068 16.0 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.1 EMG51084.1 - 0.0049 17.6 0.5 0.0094 16.7 0.2 1.5 1 1 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.1 EMG51084.1 - 0.0051 16.1 0.3 0.089 12.1 0.2 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_7 PF02796.10 EMG51084.1 - 0.012 15.4 0.2 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Acetyltransf_11 PF13720.1 EMG51084.1 - 0.016 15.3 0.1 0.025 14.7 0.0 1.4 1 1 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 HTH_Tnp_Tc3_2 PF01498.13 EMG51084.1 - 0.039 13.9 0.4 2.4 8.3 0.1 2.3 2 0 0 2 2 2 0 Transposase HTH_38 PF13936.1 EMG51084.1 - 0.049 13.1 0.1 0.38 10.3 0.0 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_11 PF08279.7 EMG51084.1 - 0.11 12.1 0.8 2.8 7.6 0.0 2.5 2 1 1 3 3 3 0 HTH domain UCH PF00443.24 EMG51085.1 - 1.8e-63 214.1 2.1 1.9e-62 210.8 1.5 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMG51085.1 - 1.1e-28 100.5 11.7 4.1e-22 78.9 0.7 2.9 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase CTP_transf_1 PF01148.15 EMG51086.1 - 1.1e-18 67.9 10.5 2.1e-16 60.3 7.3 2.1 1 1 0 1 1 1 1 Cytidylyltransferase family DUF2457 PF10446.4 EMG51086.1 - 0.14 10.8 17.2 0.19 10.3 11.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 EMG51086.1 - 0.23 9.4 11.2 0.58 8.1 7.7 1.6 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.7 EMG51086.1 - 0.48 8.2 19.5 0.62 7.9 13.5 1.0 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 EMG51086.1 - 2.6 6.9 9.8 4 6.3 6.8 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2890 PF11081.3 EMG51086.1 - 3 7.8 10.1 4.6 7.2 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Daxx PF03344.10 EMG51086.1 - 3.6 5.9 14.7 4.5 5.6 10.2 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 EMG51086.1 - 4.8 6.3 16.7 6.2 6.0 11.6 1.1 1 0 0 1 1 1 0 SDA1 VID27 PF08553.5 EMG51086.1 - 5 5.2 13.3 6.6 4.8 9.2 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Astro_capsid PF03115.9 EMG51086.1 - 10 4.2 9.7 13 3.8 6.7 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Snf7 PF03357.16 EMG51087.1 - 4.7e-23 81.4 22.2 4.7e-23 81.4 15.4 1.6 1 1 1 2 2 2 1 Snf7 Glucosaminidase PF01832.15 EMG51087.1 - 0.071 13.2 0.8 0.13 12.3 0.5 1.4 1 0 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase HD_4 PF13328.1 EMG51087.1 - 0.27 10.9 5.3 0.031 13.9 0.8 1.6 2 0 0 2 2 2 0 HD domain Eno-Rase_FAD_bd PF07055.7 EMG51087.1 - 1.2 9.1 5.1 0.37 10.7 0.5 2.4 3 0 0 3 3 3 0 Enoyl reductase FAD binding domain Pmp3 PF01679.12 EMG51088.1 - 1.3e-14 53.6 8.9 1.8e-14 53.1 6.2 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF2628 PF10947.3 EMG51088.1 - 0.22 11.3 0.7 0.38 10.5 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) DNA_pol3_delta2 PF13177.1 EMG51089.1 - 1e-13 51.2 0.2 2.2e-13 50.1 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EMG51089.1 - 4e-07 30.2 0.4 1.5e-06 28.4 0.3 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EMG51089.1 - 5e-07 29.6 0.1 2.6e-05 24.1 0.0 2.6 2 0 0 2 2 2 1 Replication factor C C-terminal domain Rad17 PF03215.10 EMG51089.1 - 7.3e-06 24.9 0.1 1e-05 24.4 0.1 1.4 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EMG51089.1 - 3.3e-05 24.0 1.6 0.00044 20.4 0.5 2.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EMG51089.1 - 0.00062 19.8 1.0 0.028 14.3 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain DNA_pol3_delta PF06144.8 EMG51089.1 - 0.0013 18.2 0.2 0.0023 17.4 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Sigma54_activ_2 PF14532.1 EMG51089.1 - 0.0015 18.6 0.0 0.033 14.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_10 PF12846.2 EMG51089.1 - 0.0087 15.5 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain T4SS-DNA_transf PF02534.9 EMG51089.1 - 0.017 13.6 0.1 0.068 11.7 0.0 1.9 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer PMSR PF01625.16 EMG51090.1 - 2e-51 173.9 0.2 2.4e-51 173.7 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase ParA PF10609.4 EMG51091.1 - 1.9e-35 120.5 0.9 8.7e-35 118.4 0.4 2.3 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 EMG51091.1 - 4e-13 49.2 0.0 8.2e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.13 EMG51091.1 - 1.2e-08 34.5 0.8 0.0036 16.5 0.1 2.5 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.6 EMG51091.1 - 3.6e-08 32.8 0.0 6.1e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 EMG51091.1 - 1.2e-07 31.7 0.1 4.3e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 EMG51091.1 - 0.00013 21.1 0.7 0.00042 19.4 0.5 1.8 1 0 0 1 1 1 1 Anion-transporting ATPase BUD22 PF09073.5 EMG51091.1 - 0.022 13.8 4.7 0.031 13.3 3.3 1.1 1 0 0 1 1 1 0 BUD22 VirC1 PF07015.6 EMG51091.1 - 0.056 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein PhnA_Zn_Ribbon PF08274.7 EMG51091.1 - 0.16 11.7 0.3 0.36 10.6 0.2 1.5 1 0 0 1 1 1 0 PhnA Zinc-Ribbon YhjQ PF06564.7 EMG51091.1 - 0.17 11.1 0.1 0.37 10.0 0.0 1.5 1 0 0 1 1 1 0 YhjQ protein TrmE_N PF10396.4 EMG51092.1 - 1.4e-33 115.2 0.0 5.4e-33 113.3 0.0 2.0 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 EMG51092.1 - 3.5e-20 72.1 1.8 5.5e-19 68.2 0.4 2.4 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTPase_Cys_C PF12631.2 EMG51092.1 - 1.6e-15 57.2 0.0 5.6e-14 52.3 0.0 2.7 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE Arf PF00025.16 EMG51092.1 - 1.9e-07 30.4 1.3 0.00015 21.0 0.3 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family FeoB_N PF02421.13 EMG51092.1 - 8.3e-07 28.4 0.6 1.4e-06 27.7 0.4 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EMG51092.1 - 5.9e-06 25.8 0.8 3.7e-05 23.2 0.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EMG51092.1 - 0.00011 22.1 0.8 0.0014 18.4 0.0 2.8 2 2 0 2 2 2 1 Dynamin family AAA_22 PF13401.1 EMG51092.1 - 0.001 19.1 0.4 0.0062 16.6 0.0 2.4 3 0 0 3 3 3 1 AAA domain Gtr1_RagA PF04670.7 EMG51092.1 - 0.0011 18.2 0.5 0.014 14.5 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EMG51092.1 - 0.0029 18.0 0.4 0.017 15.6 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 EMG51092.1 - 0.0072 15.5 0.1 0.026 13.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 eIF3_subunit PF08597.5 EMG51092.1 - 0.018 14.5 3.4 1.7 8.1 0.1 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit AAA_17 PF13207.1 EMG51092.1 - 0.023 15.4 0.1 0.12 13.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 EMG51092.1 - 0.052 13.7 1.7 0.58 10.3 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Syntaxin_2 PF14523.1 EMG51092.1 - 0.37 10.8 6.7 3.8 7.5 0.5 3.2 2 1 1 3 3 3 0 Syntaxin-like protein AAA_18 PF13238.1 EMG51092.1 - 0.52 10.6 3.8 0.69 10.2 0.6 2.8 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EMG51092.1 - 2.2 8.5 10.3 0.072 13.3 1.2 2.6 2 1 1 3 3 3 0 ABC transporter Bromodomain PF00439.20 EMG51093.1 - 5.4e-32 109.5 1.6 5e-17 61.5 0.0 3.1 3 0 0 3 3 3 2 Bromodomain CENP-B_dimeris PF09026.5 EMG51093.1 - 0.14 12.3 2.6 0.3 11.3 1.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain tRNA-synt_2d PF01409.15 EMG51094.1 - 4.8e-46 156.9 0.1 7.3e-24 84.3 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EMG51094.1 - 1.6e-28 98.7 0.0 4.1e-28 97.3 0.0 1.8 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Flavodoxin_1 PF00258.20 EMG51094.1 - 4.8e-27 94.7 0.0 4.8e-26 91.4 0.0 2.2 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.15 EMG51094.1 - 1.6e-17 63.7 0.0 1.4e-11 44.2 0.0 2.6 1 1 1 2 2 2 2 FAD binding domain NAD_binding_1 PF00175.16 EMG51094.1 - 3.1e-14 53.4 0.1 1e-13 51.7 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.2 EMG51094.1 - 0.0086 15.5 0.1 0.065 12.6 0.0 2.3 2 1 1 3 3 3 1 Flavodoxin domain tRNA-synt_2 PF00152.15 EMG51094.1 - 0.015 14.0 0.5 1.8 7.2 0.1 2.6 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) Flavodoxin_5 PF12724.2 EMG51094.1 - 0.023 14.7 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Oxidored_FMN PF00724.15 EMG51095.1 - 5.6e-92 308.3 0.0 6.3e-92 308.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family LAMTOR PF15454.1 EMG51096.1 - 9.1e-15 54.7 6.3 9.1e-15 54.7 4.4 1.7 1 1 1 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF1241 PF06840.6 EMG51096.1 - 0.044 13.0 0.2 0.069 12.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) DUF695 PF05117.7 EMG51096.1 - 0.055 13.3 0.6 0.13 12.1 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF695) DUF267 PF03268.9 EMG51096.1 - 0.49 9.1 1.8 0.67 8.7 1.2 1.1 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF267 GFO_IDH_MocA PF01408.17 EMG51097.1 - 2.3e-20 73.3 0.0 4.7e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold OpuAC PF04069.7 EMG51097.1 - 0.0088 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system NAD_binding_3 PF03447.11 EMG51097.1 - 0.024 15.0 0.0 0.045 14.1 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EMG51097.1 - 0.046 14.0 0.0 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EMG51097.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Zip PF02535.17 EMG51098.1 - 0.47 9.4 3.4 0.71 8.8 2.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 EMG51098.1 - 0.77 9.0 11.7 1.7 7.9 8.1 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Abhydrolase_1 PF00561.15 EMG51099.1 - 9.9e-21 74.3 0.3 1.6e-20 73.7 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 EMG51099.1 - 1.4e-19 69.2 0.4 3.1e-19 68.0 0.1 1.8 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EMG51099.1 - 3e-10 40.3 0.0 4.9e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMG51099.1 - 2.4e-06 27.3 0.0 7.6e-05 22.4 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EMG51099.1 - 0.0073 15.7 0.1 2.2 7.6 0.0 2.5 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Nha1_C PF08619.5 EMG51099.1 - 0.1 11.8 0.1 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF3522 PF12036.3 EMG51102.1 - 0.033 14.0 0.1 0.043 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) Viral_Beta_CD PF04530.7 EMG51102.1 - 0.14 12.3 0.5 0.16 12.1 0.4 1.3 1 0 0 1 1 1 0 Viral Beta C/D like family Zn_ribbon_recom PF13408.1 EMG51102.1 - 2.3 8.5 10.6 2.7 8.3 3.9 2.3 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain AMMECR1 PF01871.12 EMG51103.1 - 1.1e-39 135.2 0.0 1.4e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 Thiolase_N PF00108.18 EMG51104.1 - 4e-76 255.4 0.1 5.2e-76 255.1 0.1 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMG51104.1 - 1.6e-38 130.8 0.3 1e-37 128.3 0.0 2.2 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EMG51104.1 - 0.013 15.0 0.1 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain zf-C2H2_2 PF12756.2 EMG51105.1 - 0.017 15.1 0.9 0.037 14.1 0.6 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) P16-Arc PF04699.9 EMG51105.1 - 0.065 13.2 0.5 0.22 11.5 0.3 1.9 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) zf-C2H2_4 PF13894.1 EMG51105.1 - 0.14 12.5 7.7 0.11 12.9 0.6 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EMG51105.1 - 0.61 10.5 6.9 2 8.9 0.5 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type CRC_subunit PF08624.5 EMG51106.1 - 1.1e-56 190.5 0.1 2.4e-56 189.4 0.1 1.6 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit DUF3138 PF11336.3 EMG51106.1 - 0.089 10.9 0.5 0.12 10.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CDC45 PF02724.9 EMG51106.1 - 4.2 5.2 12.0 5.9 4.7 8.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 EMG51106.1 - 7.3 6.1 17.2 1.5 8.3 0.0 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region zf-C2H2_4 PF13894.1 EMG51107.1 - 4.1e-05 23.5 7.2 0.018 15.3 0.5 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EMG51107.1 - 0.00021 21.4 8.9 0.015 15.6 0.1 3.3 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-Di19 PF05605.7 EMG51107.1 - 0.015 15.4 1.7 0.04 14.0 1.0 1.9 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 EMG51107.1 - 2.6 8.4 8.5 0.73 10.2 1.4 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-H2C2_5 PF13909.1 EMG51107.1 - 9 6.7 6.6 11 6.4 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Peptidase_M41 PF01434.13 EMG51108.1 - 5.8e-73 244.8 0.0 1.1e-72 243.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EMG51108.1 - 2.2e-43 147.6 0.0 2.8e-42 144.0 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EMG51108.1 - 2e-11 44.0 0.9 4.6e-11 42.8 0.6 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.1 EMG51108.1 - 0.00024 21.9 2.9 0.00055 20.7 0.0 3.1 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.1 EMG51108.1 - 0.0013 18.9 1.9 0.1 12.7 0.3 3.3 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 EMG51108.1 - 0.0027 16.5 0.0 0.0068 15.1 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EMG51108.1 - 0.0053 16.4 0.5 0.014 15.1 0.4 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EMG51108.1 - 0.0057 15.7 0.0 0.022 13.8 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EMG51108.1 - 0.0069 15.8 0.0 0.02 14.3 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 EMG51108.1 - 0.0085 15.8 0.6 0.057 13.1 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EMG51108.1 - 0.021 14.7 2.7 0.027 14.3 0.0 2.6 4 0 0 4 4 3 0 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EMG51108.1 - 0.036 14.0 0.2 0.11 12.4 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 EMG51108.1 - 0.053 12.6 0.1 0.16 11.0 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.1 EMG51108.1 - 0.056 12.8 0.9 0.26 10.6 0.2 2.1 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 EMG51108.1 - 0.062 13.6 4.3 0.27 11.5 0.0 3.8 4 1 0 4 4 4 0 AAA domain AAA_33 PF13671.1 EMG51108.1 - 0.15 11.9 0.9 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Adap_comp_sub PF00928.16 EMG51109.1 - 1.6e-49 168.3 2.0 3e-49 167.4 1.4 1.4 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Nramp PF01566.13 EMG51110.1 - 1.8e-89 300.0 14.5 6e-89 298.3 10.1 1.7 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein DUF1352 PF07086.7 EMG51110.1 - 7.9 6.0 10.5 0.89 9.1 2.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1352) Nfu_N PF08712.6 EMG51112.1 - 1.7e-27 94.8 0.1 6e-27 93.0 0.0 1.9 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EMG51112.1 - 2.7e-22 78.3 0.1 4.3e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain ATP-synt_J PF04911.7 EMG51112.1 - 1.9e-19 68.8 0.5 3.5e-19 68.0 0.4 1.4 1 0 0 1 1 1 1 ATP synthase j chain YojJ PF10372.4 EMG51112.1 - 0.0091 15.8 0.8 0.021 14.6 0.6 1.6 1 0 0 1 1 1 1 Bacterial membrane-spanning protein N-terminus RhoGAP PF00620.22 EMG51112.1 - 0.033 13.7 0.2 0.16 11.5 0.0 2.1 3 0 0 3 3 3 0 RhoGAP domain Herpes_UL6 PF01763.11 EMG51112.1 - 0.5 8.4 2.1 1.6 6.7 1.5 1.6 1 1 0 1 1 1 0 Herpesvirus UL6 like Methyltransf_16 PF10294.4 EMG51113.1 - 2.3e-25 89.0 0.4 3.6e-25 88.4 0.3 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EMG51113.1 - 1.9e-08 33.8 0.0 3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EMG51113.1 - 5.8e-08 33.3 0.1 1.5e-07 31.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMG51113.1 - 4.6e-06 26.2 0.1 8.4e-06 25.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMG51113.1 - 6.9e-05 23.2 0.1 0.00014 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMG51113.1 - 9e-05 21.6 0.1 0.00015 20.8 0.1 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EMG51113.1 - 0.00018 21.2 0.0 0.0003 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMG51113.1 - 0.00026 21.4 0.0 0.00048 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 EMG51113.1 - 0.00052 18.8 0.0 0.0009 18.0 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase PrmA PF06325.8 EMG51113.1 - 0.0008 18.6 0.1 0.0012 18.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EMG51113.1 - 0.0028 17.6 0.0 0.0065 16.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMG51113.1 - 0.019 15.2 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TRM PF02005.11 EMG51113.1 - 0.053 12.4 0.0 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase CMAS PF02353.15 EMG51113.1 - 0.12 11.4 0.1 0.25 10.3 0.1 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Allantoicase PF03561.10 EMG51114.1 - 8.6e-99 327.2 0.6 1.5e-52 177.0 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat F5_F8_type_C PF00754.20 EMG51114.1 - 0.014 15.2 0.5 0.041 13.7 0.0 2.0 3 0 0 3 3 3 0 F5/8 type C domain DUF2422 PF10337.4 EMG51115.1 - 3.6e-134 448.0 2.0 3.6e-134 448.0 1.4 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EMG51115.1 - 1.4e-71 240.8 0.5 5.2e-71 238.8 0.1 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 EMG51115.1 - 5e-07 29.6 14.2 5e-07 29.6 9.8 2.9 2 0 0 2 2 2 1 Fusaric acid resistance protein-like DUF2422 PF10337.4 EMG51116.1 - 1.4e-140 469.1 4.7 1.4e-140 469.1 3.3 2.4 3 1 0 3 3 3 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EMG51116.1 - 3.3e-80 268.9 0.2 3.1e-78 262.5 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 EMG51116.1 - 1.2e-06 28.5 11.7 1.2e-06 28.5 8.1 2.3 2 0 0 2 2 2 1 Fusaric acid resistance protein-like Sod_Cu PF00080.15 EMG51117.1 - 3e-24 85.7 0.4 3.9e-24 85.4 0.3 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Fmp27 PF10344.4 EMG51117.1 - 0.014 13.1 0.6 0.018 12.7 0.4 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 SOG2 PF10428.4 EMG51117.1 - 0.017 13.8 5.5 0.021 13.4 3.8 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein RAP1 PF07218.6 EMG51117.1 - 0.16 10.0 16.1 0.19 9.7 11.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CDK2AP PF09806.4 EMG51117.1 - 0.33 11.1 7.4 0.53 10.4 5.1 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF515 PF04415.7 EMG51117.1 - 2.4 6.3 15.0 3.3 5.8 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Macoilin PF09726.4 EMG51117.1 - 9.5 4.3 12.7 12 4.0 8.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Exo_endo_phos PF03372.18 EMG51118.1 - 1.5e-10 41.4 0.2 1.8e-10 41.1 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Tubulin-binding PF00418.14 EMG51118.1 - 0.13 11.9 0.6 0.27 10.9 0.4 1.5 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat Exo_endo_phos PF03372.18 EMG51119.1 - 3.8e-10 40.1 0.1 5.1e-10 39.7 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EMG51119.1 - 0.00012 21.6 0.1 0.00039 20.0 0.1 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase DUF3610 PF12272.3 EMG51119.1 - 0.11 12.1 0.4 0.23 11.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3610) AA_permease_2 PF13520.1 EMG51120.1 - 1.3e-46 159.0 55.8 1.6e-46 158.7 38.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMG51120.1 - 8.2e-25 87.0 48.2 1.1e-24 86.6 33.4 1.0 1 0 0 1 1 1 1 Amino acid permease MatE PF01554.13 EMG51121.1 - 3.1e-57 192.7 32.3 2.3e-32 111.8 5.0 3.2 4 0 0 4 4 4 2 MatE Glyco_hydro_76 PF03663.9 EMG51122.1 - 1.5e-140 468.8 18.6 1.9e-140 468.4 12.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 HAD_2 PF13419.1 EMG51123.1 - 1.4e-18 67.7 0.3 3.3e-18 66.5 0.2 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMG51123.1 - 1.6e-07 30.9 0.0 3.7e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EMG51123.1 - 7.5e-06 26.5 0.0 5.5e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Fungal_trans_2 PF11951.3 EMG51124.1 - 6.5e-47 159.9 8.3 3.1e-46 157.7 5.8 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMG51124.1 - 2.1e-07 30.7 9.2 2.1e-07 30.7 6.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CtIP_N PF10482.4 EMG51124.1 - 0.05 13.4 0.1 0.05 13.4 0.0 2.3 3 0 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain AA_permease_2 PF13520.1 EMG51125.1 - 3.8e-45 154.2 57.4 4.6e-45 153.9 39.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMG51125.1 - 8.7e-19 67.2 47.0 1.1e-18 66.8 32.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2910 PF11139.3 EMG51125.1 - 0.0043 16.2 0.1 0.0043 16.2 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2910) AA_permease_2 PF13520.1 EMG51126.1 - 7.6e-41 140.0 59.8 9.5e-41 139.7 41.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMG51126.1 - 6.6e-16 57.7 49.5 8.7e-16 57.3 34.3 1.1 1 0 0 1 1 1 1 Amino acid permease CBFD_NFYB_HMF PF00808.18 EMG51128.1 - 4.4e-09 36.2 0.2 8.6e-09 35.3 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMG51128.1 - 3.2e-07 30.3 0.1 5.9e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 BUD22 PF09073.5 EMG51128.1 - 0.004 16.2 36.1 0.0052 15.9 25.0 1.1 1 0 0 1 1 1 1 BUD22 TrmB PF01978.14 EMG51128.1 - 0.083 12.6 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB CDC27 PF09507.5 EMG51128.1 - 0.44 9.7 31.9 0.59 9.2 22.1 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Transposase_24 PF03004.9 EMG51129.1 - 0.046 13.5 0.2 0.057 13.3 0.1 1.1 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) HA2 PF04408.18 EMG51130.1 - 6.4e-22 77.5 0.0 2.2e-21 75.7 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EMG51130.1 - 3e-13 49.4 0.0 1.1e-12 47.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EMG51130.1 - 9.4e-09 35.1 0.0 3e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EMG51130.1 - 3.5e-08 33.1 0.0 7.8e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EMG51130.1 - 0.00078 19.5 0.0 0.003 17.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EMG51130.1 - 0.035 13.0 0.0 0.1 11.4 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein 2Fe-2S_thioredx PF01257.14 EMG51131.1 - 1.5e-59 199.7 0.2 1.9e-59 199.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin U1snRNP70_N PF12220.3 EMG51132.1 - 0.2 12.0 3.7 0.24 11.7 2.5 1.1 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Nefa_Nip30_N PF10187.4 EMG51132.1 - 0.26 11.5 2.3 0.3 11.2 1.6 1.1 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF4613 PF15390.1 EMG51132.1 - 0.28 9.2 1.1 0.28 9.3 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) WD40 PF00400.27 EMG51134.1 - 2.6e-36 122.1 8.7 1.2e-07 31.3 0.0 6.1 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EMG51134.1 - 3.3e-07 30.2 0.9 0.00016 21.4 0.2 2.9 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A MOZ_SAS PF01853.13 EMG51135.1 - 8.6e-51 171.8 0.7 1.2e-50 171.3 0.5 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-C2H2 PF00096.21 EMG51135.1 - 0.0029 17.8 1.3 0.0072 16.6 0.9 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMG51135.1 - 0.051 13.9 1.3 0.17 12.2 0.9 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger SNF2_N PF00176.18 EMG51136.1 - 3.3e-68 229.6 0.5 5.3e-68 229.0 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMG51136.1 - 1.5e-10 40.8 0.0 3.1e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.6 EMG51136.1 - 1.7e-10 40.7 0.0 4.9e-10 39.2 0.0 1.9 1 0 0 1 1 1 1 HIRAN domain zf-RING_2 PF13639.1 EMG51136.1 - 1.7e-07 30.9 9.2 3.3e-07 30.0 6.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMG51136.1 - 3.5e-06 26.5 10.7 7.2e-06 25.5 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMG51136.1 - 3.6e-06 26.5 6.7 6.3e-06 25.7 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMG51136.1 - 9.2e-06 25.2 8.7 1.9e-05 24.3 6.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMG51136.1 - 1.6e-05 24.7 9.6 3.5e-05 23.7 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 EMG51136.1 - 4.4e-05 23.3 0.8 0.00016 21.5 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Dot_icm_IcmQ PF09475.5 EMG51136.1 - 0.0033 16.6 0.0 1 8.5 0.0 2.8 2 0 0 2 2 2 1 Dot/Icm secretion system protein (dot_icm_IcmQ) zf-C3HC4_4 PF15227.1 EMG51136.1 - 0.0061 16.4 9.3 0.015 15.1 6.4 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EMG51136.1 - 0.03 14.1 1.9 0.17 11.7 1.3 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EMG51136.1 - 0.034 13.7 4.5 0.081 12.5 3.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EMG51136.1 - 0.43 10.3 6.6 1.1 9.0 4.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.2 EMG51136.1 - 0.85 9.7 11.9 0.3 11.2 4.8 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger Peptidase_M24 PF00557.19 EMG51137.1 - 9.2e-35 120.0 0.0 1.7e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EMG51137.1 - 1.3e-16 61.2 0.0 5.3e-13 49.5 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Rep_fac-A_C PF08646.5 EMG51139.1 - 2.8e-49 166.5 6.9 2.5e-48 163.4 0.8 3.0 3 1 0 3 3 3 2 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 EMG51139.1 - 3.6e-16 58.7 2.2 1.4e-08 34.4 0.0 4.5 3 1 0 4 4 4 3 OB-fold nucleic acid binding domain Rep-A_N PF04057.7 EMG51139.1 - 3.6e-13 49.1 0.2 7.4e-13 48.1 0.1 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain DUF223 PF02721.9 EMG51139.1 - 0.00013 21.9 0.2 0.00045 20.2 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function DUF223 Cys_Met_Meta_PP PF01053.15 EMG51140.1 - 6.7e-136 452.5 0.0 7.8e-136 452.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.6 EMG51140.1 - 3.7e-06 25.5 0.0 3.5e-05 22.2 0.0 2.0 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.16 EMG51140.1 - 2.1e-05 23.6 0.0 3.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EMG51140.1 - 2.4e-05 23.5 0.0 4.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EMG51140.1 - 0.0046 15.7 0.1 0.01 14.5 0.0 1.6 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EMG51140.1 - 0.038 13.1 0.1 0.14 11.3 0.0 1.7 1 1 0 1 1 1 0 Beta-eliminating lyase GDC-P PF02347.11 EMG51140.1 - 0.12 11.0 0.0 0.22 10.1 0.0 1.5 1 0 0 1 1 1 0 Glycine cleavage system P-protein Aminotran_1_2 PF00155.16 EMG51141.1 - 1.7e-06 27.2 0.0 2.1e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1406 PF07190.6 EMG51141.1 - 0.027 14.1 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1406) DegT_DnrJ_EryC1 PF01041.12 EMG51141.1 - 0.12 11.3 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Sel1 PF08238.7 EMG51141.1 - 0.14 12.8 0.0 0.74 10.5 0.0 2.3 3 0 0 3 3 3 0 Sel1 repeat HABP4_PAI-RBP1 PF04774.10 EMG51142.1 - 4e-05 24.0 1.7 5.1e-05 23.7 1.2 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family ORF6N PF10543.4 EMG51142.1 - 0.23 11.5 1.3 0.59 10.2 0.3 1.8 2 0 0 2 2 2 0 ORF6N domain CTP_transf_2 PF01467.21 EMG51143.1 - 1.1e-21 77.5 0.0 1.1e-12 48.2 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 EMG51143.1 - 0.00021 20.9 0.0 0.011 15.3 0.0 2.7 3 0 0 3 3 3 1 FAD synthetase DUF3370 PF11850.3 EMG51143.1 - 0.058 11.8 0.0 0.099 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3370) DUF4112 PF13430.1 EMG51144.1 - 1.1e-30 105.6 0.3 2e-30 104.7 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) zf-CCCH PF00642.19 EMG51144.1 - 2e-09 36.9 1.9 3.9e-09 35.9 1.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 EMG51144.1 - 4.5e-08 32.9 5.6 9.9e-08 31.8 3.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMG51144.1 - 8.9e-06 25.2 5.4 1.9e-05 24.2 3.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMG51144.1 - 4.5e-05 23.1 3.9 9.4e-05 22.1 2.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMG51144.1 - 0.00016 21.2 3.7 0.00034 20.2 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMG51144.1 - 0.002 17.7 6.4 0.002 17.7 4.4 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMG51144.1 - 0.0022 17.8 5.4 0.0054 16.5 3.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMG51144.1 - 0.011 15.4 2.4 0.037 13.7 1.6 2.0 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 EMG51144.1 - 0.024 14.1 1.4 0.068 12.7 1.0 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Spt20 PF12090.3 EMG51144.1 - 0.17 11.1 7.0 0.061 12.6 1.6 2.1 2 0 0 2 2 2 0 Spt20 family PAT1 PF09770.4 EMG51144.1 - 6.4 4.8 26.6 9.6 4.3 18.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HSCB_C PF07743.8 EMG51145.1 - 1.5e-13 51.0 4.5 2.4e-13 50.3 3.1 1.3 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EMG51145.1 - 1.1e-07 31.4 0.9 2.6e-07 30.2 0.0 2.0 2 1 0 2 2 2 1 DnaJ domain GLF PF03275.8 EMG51145.1 - 0.047 13.2 0.3 0.062 12.8 0.2 1.3 1 0 0 1 1 1 0 UDP-galactopyranose mutase SURF6 PF04935.7 EMG51145.1 - 0.083 12.1 1.1 0.1 11.8 0.8 1.1 1 0 0 1 1 1 0 Surfeit locus protein 6 CK_II_beta PF01214.13 EMG51146.1 - 7.2e-69 230.9 1.3 4e-68 228.5 0.9 2.0 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Secretin_N_2 PF07655.8 EMG51146.1 - 0.27 11.6 8.6 0.47 10.8 5.9 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain TLP-20 PF06088.6 EMG51146.1 - 0.37 10.4 7.9 1.3 8.7 0.3 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Senescence_reg PF04520.8 EMG51146.1 - 0.46 10.9 5.5 0.27 11.7 0.3 2.1 2 0 0 2 2 2 0 Senescence regulator DUF2600 PF10776.4 EMG51146.1 - 2.3 6.9 5.3 7.4 5.3 3.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2600) DUF912 PF06024.7 EMG51146.1 - 3 7.9 9.4 0.056 13.4 1.2 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RXT2_N PF08595.6 EMG51146.1 - 7.6 6.3 14.8 11 5.8 5.9 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal WD40 PF00400.27 EMG51147.1 - 2.5e-45 150.7 15.9 3.6e-09 36.1 0.1 7.8 7 1 1 8 8 8 6 WD domain, G-beta repeat Hira PF07569.6 EMG51147.1 - 6.3e-16 58.2 0.2 1.4e-15 57.1 0.1 1.6 1 0 0 1 1 1 1 TUP1-like enhancer of split HIRA_B PF09453.5 EMG51147.1 - 4.2e-10 38.8 1.3 1e-09 37.6 0.9 1.7 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 EMG51147.1 - 2.8e-05 23.6 0.5 21 4.9 0.0 4.7 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EMG51147.1 - 0.029 13.4 0.0 4.4 6.3 0.0 3.0 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Reg_prop PF07494.6 EMG51147.1 - 0.14 12.2 1.1 47 4.5 0.0 3.6 3 0 0 3 3 3 0 Two component regulator propeller TFIIIC_delta PF12657.2 EMG51147.1 - 0.35 10.5 3.8 1.1 8.8 0.3 3.3 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Aminotran_1_2 PF00155.16 EMG51148.1 - 5.5e-05 22.2 0.0 7e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II