# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Transposase_20 PF02371.16 KND95391.1 - 1.2e-21 76.8 0.0 1.8e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DUF4020 PF13212.6 KND95391.1 - 0.09 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) PanZ PF12568.8 KND95392.1 - 0.0049 16.6 0.0 0.0057 16.4 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ LSDAT_euk PF18139.1 KND95398.1 - 0.21 11.0 1.2 11 5.3 0.1 2.1 2 0 0 2 2 2 0 SLOG in TRPM Mastoparan_2 PF08251.11 KND95398.1 - 0.41 11.0 1.5 53 4.5 0.1 3.1 2 0 0 2 2 2 0 Mastoparan peptide PSGP PF07276.11 KND95398.1 - 1.1 9.8 7.7 14 6.4 0.9 2.8 2 0 0 2 2 2 0 Apopolysialoglycoprotein (PSGP) 2-oxogl_dehyd_N PF16078.5 KND95404.1 - 0.15 11.6 0.2 0.26 10.9 0.2 1.3 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus MFS_1 PF07690.16 KND95408.1 - 2e-38 132.3 21.3 4.4e-38 131.1 21.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Myc_target_1 PF15179.6 KND95408.1 - 0.21 11.5 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 Myc target protein 1 Fer4_2 PF12797.7 KND95411.1 - 0.052 13.7 1.0 0.076 13.1 1.0 1.2 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4 PF00037.27 KND95411.1 - 0.098 12.5 0.7 0.13 12.2 0.7 1.2 1 0 0 1 1 1 0 4Fe-4S binding domain SVA PF05326.11 KND95413.1 - 0.5 10.4 2.4 0.53 10.3 1.6 1.5 1 1 0 1 1 1 0 Seminal vesicle autoantigen (SVA) BRCT PF00533.26 KND95415.1 - 2.3e-24 85.6 3.6 9.1e-07 29.2 0.0 4.8 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KND95415.1 - 1.5e-19 69.7 4.7 1.6e-06 28.0 0.1 5.0 5 0 0 5 5 5 4 twin BRCT domain BRCT_2 PF16589.5 KND95415.1 - 3.9e-09 36.8 0.0 0.00076 19.8 0.0 4.1 4 0 0 4 4 4 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KND95415.1 - 0.0051 17.1 0.3 1.2 9.5 0.0 3.5 3 0 0 3 3 3 1 DNA ligase 3 BRCT domain DUF2009 PF09418.10 KND95418.1 - 0.027 13.5 0.1 0.03 13.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) DUF2462 PF09495.10 KND95421.1 - 8.4e-17 61.7 7.4 8.4e-17 61.7 7.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) CTV_P6 PF06706.11 KND95422.1 - 0.0053 16.4 0.4 0.0053 16.4 0.4 1.6 2 0 0 2 2 2 1 Citrus tristeza virus 6-kDa protein Ferric_reduct PF01794.19 KND95422.1 - 0.03 14.4 1.0 0.036 14.2 1.0 1.1 1 0 0 1 1 1 0 Ferric reductase like transmembrane component TadE PF07811.12 KND95422.1 - 0.064 13.5 0.8 0.13 12.5 0.2 1.8 2 0 0 2 2 2 0 TadE-like protein Baculo_E56 PF04639.12 KND95422.1 - 0.087 12.1 0.2 0.24 10.6 0.0 1.6 2 0 0 2 2 2 0 Baculoviral E56 protein, specific to ODV envelope DUF2157 PF09925.9 KND95422.1 - 0.13 12.0 0.2 2.3 8.0 0.0 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) RNA_pol_Rpb8 PF03870.15 KND95423.1 - 9.2e-45 152.2 0.1 1e-44 152.1 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KND95423.1 - 1.5e-07 31.5 0.5 0.013 15.5 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G Lambda_CIII PF02061.16 KND95424.1 - 0.12 12.5 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Lambda Phage CIII Mannosyl_trans3 PF11051.8 KND95425.1 - 4.1e-36 124.7 0.0 6.4e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative DUF2470 PF10615.9 KND95427.1 - 3.1e-12 46.9 0.0 5.5e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Spindle_Spc25 PF08234.12 KND95429.1 - 2.7e-18 66.0 1.8 1.4e-17 63.6 0.0 2.9 3 1 1 4 4 3 1 Chromosome segregation protein Spc25 HBM PF16591.5 KND95429.1 - 0.0013 18.2 6.2 0.0023 17.4 6.2 1.4 1 0 0 1 1 1 1 Helical bimodular sensor domain TolA_bind_tri PF16331.5 KND95429.1 - 0.0017 18.4 5.7 0.0068 16.5 0.5 2.6 2 0 0 2 2 2 1 TolA binding protein trimerisation Dynactin_p22 PF07426.11 KND95429.1 - 0.0022 17.9 7.2 0.031 14.1 0.5 2.7 1 1 1 2 2 2 1 Dynactin subunit p22 DUF5098 PF17023.5 KND95429.1 - 0.0049 15.9 4.8 0.0059 15.6 4.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5098) TMF_DNA_bd PF12329.8 KND95429.1 - 0.0062 16.5 20.2 0.24 11.4 4.8 2.3 1 1 1 2 2 2 2 TATA element modulatory factor 1 DNA binding MPS2 PF17060.5 KND95429.1 - 0.0085 15.4 5.7 0.011 15.0 5.7 1.2 1 0 0 1 1 1 1 Monopolar spindle protein 2 TMPIT PF07851.13 KND95429.1 - 0.014 14.6 8.5 0.023 13.9 8.5 1.3 1 0 0 1 1 1 0 TMPIT-like protein WEMBL PF05701.11 KND95429.1 - 0.015 14.0 15.1 0.019 13.7 13.6 1.7 1 1 1 2 2 2 0 Weak chloroplast movement under blue light DUF724 PF05266.14 KND95429.1 - 0.02 14.7 11.5 0.028 14.2 11.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Filament PF00038.21 KND95429.1 - 0.022 14.4 11.8 0.034 13.7 11.1 1.6 1 1 0 1 1 1 0 Intermediate filament protein DUF1664 PF07889.12 KND95429.1 - 0.029 14.4 12.5 0.22 11.6 8.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF812 PF05667.11 KND95429.1 - 0.043 12.7 12.2 0.054 12.4 12.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) EzrA PF06160.12 KND95429.1 - 0.052 11.7 12.2 0.11 10.6 12.2 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA AAA_13 PF13166.6 KND95429.1 - 0.058 12.0 10.8 0.077 11.6 10.8 1.1 1 0 0 1 1 1 0 AAA domain DUF4988 PF16378.5 KND95429.1 - 0.063 12.9 4.6 0.23 11.1 3.2 2.1 1 1 1 2 2 2 0 Domain of unknown function Halo_GVPC PF05465.13 KND95429.1 - 0.065 13.5 0.9 0.42 10.9 0.0 2.6 3 0 0 3 3 2 0 Halobacterial gas vesicle protein C (GVPC) repeat Exonuc_VII_L PF02601.15 KND95429.1 - 0.098 12.2 6.4 0.13 11.8 6.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit NPV_P10 PF05531.12 KND95429.1 - 0.11 13.0 10.2 9.7 6.7 1.9 3.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein LPP PF04728.13 KND95429.1 - 0.11 12.9 5.4 2.8 8.4 0.8 2.9 1 1 2 3 3 3 0 Lipoprotein leucine-zipper BRE1 PF08647.11 KND95429.1 - 0.12 12.5 17.3 0.26 11.4 4.6 2.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase TRAF_BIRC3_bd PF16673.5 KND95429.1 - 0.14 11.9 10.4 0.13 12.1 6.1 2.8 1 1 1 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain JIP_LZII PF16471.5 KND95429.1 - 0.16 12.2 10.5 1.6 9.0 2.2 2.8 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DHR10 PF18595.1 KND95429.1 - 0.18 11.9 17.1 0.093 12.8 13.4 2.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF4407 PF14362.6 KND95429.1 - 0.22 10.9 8.0 0.3 10.4 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 KND95429.1 - 0.22 10.8 10.9 0.14 11.5 8.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) BST2 PF16716.5 KND95429.1 - 0.27 11.8 13.4 1.4 9.5 2.8 2.6 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 TPR_MLP1_2 PF07926.12 KND95429.1 - 0.29 11.2 19.6 15 5.7 14.0 3.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.9 KND95429.1 - 0.29 11.4 11.2 1.3 9.4 5.1 3.1 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fmp27_WPPW PF10359.9 KND95429.1 - 0.31 9.8 8.5 0.43 9.4 8.5 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF1192 PF06698.11 KND95429.1 - 0.32 11.1 2.7 0.42 10.7 0.3 2.4 2 1 0 2 2 1 0 Protein of unknown function (DUF1192) IFT57 PF10498.9 KND95429.1 - 0.33 9.9 13.1 0.55 9.2 13.1 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DUF948 PF06103.11 KND95429.1 - 0.35 11.1 9.5 0.75 10.1 5.7 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.9 KND95429.1 - 0.43 10.6 17.5 1.8 8.6 8.3 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PHM7_cyt PF14703.6 KND95429.1 - 0.45 10.7 7.6 1.2 9.4 0.7 2.1 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter FAM76 PF16046.5 KND95429.1 - 0.46 9.8 9.5 0.58 9.5 9.5 1.1 1 0 0 1 1 1 0 FAM76 protein Fib_alpha PF08702.10 KND95429.1 - 0.49 10.6 10.0 0.95 9.6 10.0 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Cnn_1N PF07989.11 KND95429.1 - 0.56 10.4 14.9 3 8.1 2.3 2.6 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 ADIP PF11559.8 KND95429.1 - 0.57 10.3 13.9 0.52 10.4 12.2 1.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding OmpH PF03938.14 KND95429.1 - 0.58 10.5 15.7 0.29 11.5 3.4 2.7 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Spc7 PF08317.11 KND95429.1 - 0.61 8.9 16.4 1.1 8.1 16.4 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Cytochrom_B562 PF07361.11 KND95429.1 - 0.63 10.7 10.2 3.2 8.5 0.6 3.2 1 1 1 3 3 3 0 Cytochrome b562 ApoO PF09769.9 KND95429.1 - 0.7 9.9 3.6 2.7 8.0 1.0 2.5 1 1 1 2 2 2 0 Apolipoprotein O Spc29 PF17082.5 KND95429.1 - 0.79 9.5 8.0 0.49 10.2 2.3 2.1 1 1 0 1 1 1 0 Spindle Pole Component 29 bZIP_1 PF00170.21 KND95429.1 - 0.81 9.8 11.2 3.3 7.9 1.5 2.7 2 0 0 2 2 2 0 bZIP transcription factor V_ATPase_I PF01496.19 KND95429.1 - 1.1 7.2 8.0 1.2 6.9 8.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FliJ PF02050.16 KND95429.1 - 1.2 9.4 13.1 0.41 10.9 6.1 2.6 1 1 1 2 2 2 0 Flagellar FliJ protein FlaC_arch PF05377.11 KND95429.1 - 1.4 9.4 10.6 7.1 7.1 2.2 3.0 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) 5_nucleotid PF05761.14 KND95429.1 - 1.5 7.7 7.6 2.5 6.9 7.6 1.5 1 1 0 1 1 1 0 5' nucleotidase family DivIC PF04977.15 KND95429.1 - 1.5 8.7 11.5 0.48 10.2 3.5 2.5 1 1 1 2 2 2 0 Septum formation initiator ATG16 PF08614.11 KND95429.1 - 1.6 8.9 17.0 0.72 10.0 12.6 1.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF16 PF01519.16 KND95429.1 - 1.7 9.2 18.6 0.47 11.0 8.7 2.8 2 1 1 3 3 2 0 Protein of unknown function DUF16 Atg14 PF10186.9 KND95429.1 - 1.9 7.5 9.4 2.6 7.1 9.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Seryl_tRNA_N PF02403.22 KND95429.1 - 2 8.6 15.1 4.1 7.7 3.8 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Snapin_Pallidin PF14712.6 KND95429.1 - 3 8.3 13.2 6 7.4 2.1 2.7 1 1 0 2 2 2 0 Snapin/Pallidin Syntaxin-6_N PF09177.11 KND95429.1 - 3.2 8.4 8.8 18 6.0 8.8 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF2400 PF09674.10 KND95429.1 - 3.5 7.6 6.2 4.3 7.3 4.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) APG6_N PF17675.1 KND95429.1 - 4.8 7.7 14.8 17 6.0 14.9 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 KND95429.1 - 5.8 7.6 18.4 1.6 9.4 4.2 4.0 3 2 1 4 4 3 0 SlyX zf-C4H2 PF10146.9 KND95429.1 - 6.1 7.1 12.4 60 3.9 12.4 2.0 1 1 0 1 1 1 0 Zinc finger-containing protein Spc24 PF08286.11 KND95429.1 - 7.2 6.9 15.1 3.8 7.8 3.0 2.7 2 1 1 3 3 2 0 Spc24 subunit of Ndc80 CLZ PF16526.5 KND95429.1 - 7.2 7.1 14.0 55 4.2 2.1 3.7 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Rho_Binding PF08912.11 KND95429.1 - 7.3 7.5 16.3 1.3 9.9 0.5 3.2 2 1 1 3 3 3 0 Rho Binding Phage_GPO PF05929.11 KND95429.1 - 7.5 6.1 11.7 15 5.1 2.3 1.8 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Cep57_CLD_2 PF14197.6 KND95429.1 - 8.1 6.6 13.7 27 4.9 0.2 3.9 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 Exo_endo_phos PF03372.23 KND95430.1 - 2.9e-14 53.1 0.0 4.3e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2222 PF09984.9 KND95432.1 - 0.021 14.7 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised signal transduction histidine kinase domain (DUF2222) G-patch PF01585.23 KND95433.1 - 2.2e-10 40.2 1.9 5e-10 39.1 1.9 1.7 1 0 0 1 1 1 1 G-patch domain R3H PF01424.22 KND95433.1 - 0.0033 17.4 0.0 0.017 15.1 0.0 2.2 2 0 0 2 2 2 1 R3H domain Peptidase_C54 PF03416.19 KND95434.1 - 4.8e-71 239.4 0.0 6.1e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Ssu72 PF04722.13 KND95435.1 - 6.1e-71 237.9 0.6 6.9e-71 237.8 0.6 1.0 1 0 0 1 1 1 1 Ssu72-like protein Plus-3 PF03126.18 KND95435.1 - 0.013 16.0 0.3 0.02 15.4 0.3 1.3 1 0 0 1 1 1 0 Plus-3 domain POP1 PF06978.11 KND95436.1 - 1.9e-38 132.6 0.8 2.8e-38 132.0 0.8 1.3 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KND95436.1 - 6.3e-18 64.9 0.5 1.2e-17 64.0 0.5 1.5 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.21 KND95436.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain DUF4474 PF14751.6 KND95437.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4474) LRR_4 PF12799.7 KND95437.1 - 3.9 8.0 8.6 30 5.2 2.6 4.3 3 2 0 3 3 3 0 Leucine Rich repeats (2 copies) AP3D1 PF06375.11 KND95439.1 - 0.1 12.8 4.5 0.12 12.6 4.5 1.0 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Peptidase_S24 PF00717.23 KND95440.1 - 5.6e-09 35.8 0.0 8.7e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like V-ATPase_H_C PF11698.8 KND95441.1 - 0.057 13.5 0.1 0.14 12.2 0.1 1.7 1 1 1 2 2 2 0 V-ATPase subunit H Elong_Iki1 PF10483.9 KND95442.1 - 2.4e-63 214.4 0.0 2.8e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 Elongator subunit Iki1 HEAT_2 PF13646.6 KND95443.1 - 2.1e-13 50.4 9.2 0.0037 17.6 0.3 8.1 6 2 2 8 8 8 4 HEAT repeats HEAT_EZ PF13513.6 KND95443.1 - 3.3e-09 37.0 6.8 0.19 12.3 0.0 8.2 8 0 0 8 8 8 1 HEAT-like repeat Adaptin_N PF01602.20 KND95443.1 - 1.7e-08 33.5 1.1 0.00011 20.9 0.0 3.3 1 1 1 3 3 3 2 Adaptin N terminal region HEAT PF02985.22 KND95443.1 - 3e-07 30.1 8.3 1.8 9.0 0.1 8.1 7 0 0 7 7 7 2 HEAT repeat NUC173 PF08161.12 KND95443.1 - 4.4e-06 26.5 1.9 0.11 12.1 0.1 4.0 4 1 1 5 5 5 2 NUC173 domain IFRD PF05004.13 KND95443.1 - 6.1e-05 22.3 0.0 0.39 9.8 0.0 4.0 4 1 0 4 4 4 2 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 KND95443.1 - 0.00075 19.6 5.4 4.4 7.3 0.0 4.8 3 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 KND95443.1 - 0.0015 18.4 0.4 1.7 8.6 0.0 4.8 6 0 0 6 6 6 1 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 KND95443.1 - 0.0039 17.7 0.1 17 6.1 0.0 4.7 5 1 0 6 6 6 0 Vacuolar 14 Fab1-binding region Arm PF00514.23 KND95443.1 - 0.0091 16.0 1.6 6.5 6.9 0.1 5.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 KND95443.1 - 0.18 10.9 9.9 1.5 7.9 0.8 3.9 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal XPG_N PF00752.17 KND95444.1 - 5.8e-34 116.6 0.0 2.2e-33 114.8 0.0 2.1 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KND95444.1 - 6.2e-27 93.8 0.0 2.7e-26 91.7 0.0 2.2 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 KND95444.1 - 0.00056 20.5 0.0 0.0026 18.3 0.0 2.2 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.16 KND95444.1 - 0.0098 16.2 0.1 0.036 14.4 0.0 1.9 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family SLX9 PF15341.6 KND95445.1 - 9.2 6.7 13.6 0.12 12.8 3.3 2.9 2 1 0 2 2 2 0 Ribosome biogenesis protein SLX9 H2TH PF06831.14 KND95447.1 - 8.3e-17 61.0 0.0 1.6e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 KND95447.1 - 3.2e-09 37.4 0.0 7.3e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain Pirin_C PF05726.13 KND95447.1 - 0.021 15.2 0.0 0.049 14.0 0.0 1.6 1 0 0 1 1 1 0 Pirin C-terminal cupin domain FbpA PF05833.11 KND95447.1 - 0.031 13.0 0.0 0.047 12.4 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Malic_M PF03949.15 KND95448.1 - 1.4e-81 273.6 0.0 1.9e-81 273.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KND95448.1 - 1.6e-61 207.3 0.0 2.4e-61 206.7 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Say1_Mug180 PF10340.9 KND95449.1 - 7e-31 107.4 0.0 9.4e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 KND95449.1 - 8.3e-14 52.0 0.0 1.3e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KND95449.1 - 0.057 12.3 0.0 0.094 11.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme ADK PF00406.22 KND95450.1 - 4.2e-61 205.5 0.0 5.4e-61 205.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KND95450.1 - 1.1e-22 81.0 0.3 2.9e-22 79.6 0.1 1.7 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 KND95450.1 - 2.5e-16 59.3 0.0 5.8e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KND95450.1 - 9.1e-06 26.2 0.0 1.7e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KND95450.1 - 1.6e-05 25.1 0.0 3.6e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KND95450.1 - 0.066 12.9 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KND95450.1 - 0.067 12.9 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase TSC22 PF01166.18 KND95450.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family AAA_28 PF13521.6 KND95450.1 - 0.19 12.0 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain CFIA_Pcf11 PF11526.8 KND95451.1 - 3.2e-13 50.0 4.4 2.5e-12 47.1 4.4 2.3 1 1 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 zf_UBZ PF18439.1 KND95451.1 - 0.85 9.3 8.6 1.2 8.8 3.5 3.1 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Mito_carr PF00153.27 KND95452.1 - 6.8e-31 106.1 3.5 1.3e-15 57.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ATP_bind_2 PF03668.15 KND95453.1 - 0.046 13.0 0.5 0.081 12.2 0.0 1.6 2 0 0 2 2 2 0 P-loop ATPase protein family BP28CT PF08146.12 KND95453.1 - 0.15 11.9 2.3 0.19 11.6 0.0 2.1 2 1 0 2 2 2 0 BP28CT (NUC211) domain Flocculin_t3 PF13928.6 KND95458.1 - 1.7e-18 66.8 102.2 5.8e-07 29.9 24.9 5.0 4 1 1 5 5 5 3 Flocculin type 3 repeat Cdc13_OB4_dimer PF18233.1 KND95458.1 - 0.13 12.4 4.3 29 4.8 0.1 3.3 3 0 0 3 3 3 0 Cdc13 OB4 dimerization domain TM1506 PF08973.10 KND95458.1 - 0.36 10.5 2.4 28 4.4 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1893) FANCL_C PF11793.8 KND95458.1 - 0.93 9.7 15.6 6 7.1 1.4 3.5 4 0 0 4 4 4 0 FANCL C-terminal domain SapA PF02199.15 KND95458.1 - 2.7 8.3 9.5 59 4.1 0.3 3.9 3 0 0 3 3 3 0 Saposin A-type domain zf-H2C2_2 PF13465.6 KND95459.1 - 0.0073 16.7 0.2 0.0095 16.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger double domain FAD_binding_1 PF00667.20 KND95461.1 - 2.5e-67 226.7 0.0 3.9e-67 226.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KND95461.1 - 2.7e-08 34.4 0.0 6.7e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 KND95461.1 - 0.0033 17.7 0.1 0.009 16.3 0.1 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II POR PF01558.18 KND95461.1 - 0.062 13.4 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase FAD_binding_6 PF00970.24 KND95461.1 - 0.077 13.4 0.0 0.27 11.6 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain FAD-oxidase_C PF02913.19 KND95462.1 - 2.1e-50 171.7 0.0 3.5e-50 171.0 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KND95462.1 - 5.2e-31 107.3 0.1 1e-30 106.3 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain YL1_C PF08265.11 KND95463.1 - 1.3e-12 47.2 0.0 2.3e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Sedlin_N PF04628.13 KND95464.1 - 2.2e-20 73.1 0.0 2.6e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region BAG PF02179.16 KND95466.1 - 1.6e-21 76.5 3.5 1.6e-21 76.5 3.5 2.0 3 0 0 3 3 3 1 BAG domain AATF-Che1 PF13339.6 KND95466.1 - 0.0059 17.3 2.6 0.0059 17.3 2.6 1.7 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor BCIP PF13862.6 KND95466.1 - 0.0077 16.0 2.5 0.0077 16.0 2.5 2.2 1 1 0 2 2 2 1 p21-C-terminal region-binding protein Transpeptidase PF00905.22 KND95466.1 - 0.045 13.0 2.0 0.065 12.4 1.7 1.4 1 1 0 1 1 1 0 Penicillin binding protein transpeptidase domain AgrB PF04647.15 KND95466.1 - 0.11 11.8 3.4 3.8 6.8 0.4 2.3 2 0 0 2 2 2 0 Accessory gene regulator B Nucleos_tra2_C PF07662.13 KND95466.1 - 0.17 11.7 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter C-terminus FdhE PF04216.12 KND95466.1 - 0.19 11.6 2.9 1.1 9.1 1.4 2.0 1 1 1 2 2 2 0 Protein involved in formate dehydrogenase formation Serinc PF03348.15 KND95466.1 - 0.23 10.4 2.1 0.31 9.9 2.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) CLN3 PF02487.17 KND95466.1 - 0.42 9.6 1.6 0.55 9.2 1.6 1.1 1 0 0 1 1 1 0 CLN3 protein HI0933_like PF03486.14 KND95466.1 - 0.78 8.4 7.6 1.7 7.3 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Phage_int_SAM_5 PF13102.6 KND95466.1 - 0.8 10.1 11.0 1.5 9.2 0.2 3.0 3 1 1 4 4 4 0 Phage integrase SAM-like domain DUF1054 PF06335.12 KND95466.1 - 0.81 9.6 7.8 0.41 10.5 5.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1054) LAM_C PF12544.8 KND95466.1 - 2.4 8.3 9.3 7.8 6.7 3.9 2.8 1 1 1 2 2 2 0 Lysine-2,3-aminomutase DOPA_dioxygen PF08883.11 KND95467.1 - 1.1e-31 109.2 0.3 1.3e-31 108.9 0.3 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family DnaJ-X PF14308.6 KND95468.1 - 5.7e-83 277.5 16.2 5.7e-83 277.5 16.2 3.3 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 KND95468.1 - 1e-24 86.4 0.6 3.1e-24 84.9 0.6 1.9 1 0 0 1 1 1 1 DnaJ domain Ribosomal_S5_C PF03719.15 KND95469.1 - 1.9e-23 81.7 0.0 4.4e-23 80.5 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KND95469.1 - 4.7e-18 64.9 0.5 7.8e-18 64.2 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DUF2838 PF10998.8 KND95470.1 - 2e-36 124.6 12.0 2e-36 124.6 12.0 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) PRESAN PF09687.10 KND95470.1 - 0.013 16.1 0.2 0.076 13.6 0.1 2.1 2 0 0 2 2 2 0 Plasmodium RESA N-terminal Pox_A_type_inc PF04508.12 KND95470.1 - 0.046 13.6 0.2 0.087 12.7 0.2 1.4 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF16 PF01519.16 KND95470.1 - 1.7 9.2 10.0 21 5.6 0.1 3.3 2 1 0 2 2 2 0 Protein of unknown function DUF16 RRM_1 PF00076.22 KND95471.1 - 3e-24 84.6 0.1 9.8e-15 54.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KND95471.1 - 0.0081 16.3 0.0 3.7 7.7 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KND95471.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ADH_N PF08240.12 KND95473.1 - 8.8e-30 102.8 1.1 1.5e-29 102.1 1.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KND95473.1 - 6.5e-28 97.3 0.1 1.2e-27 96.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KND95473.1 - 4.8e-06 27.6 0.0 9.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KND95473.1 - 0.088 12.3 0.4 0.18 11.2 0.2 1.6 1 1 0 1 1 1 0 short chain dehydrogenase Eisosome1 PF12757.7 KND95474.1 - 2e-10 41.0 0.5 2e-10 41.0 0.5 8.9 4 3 0 5 5 5 1 Eisosome protein 1 Baculo_PEP_C PF04513.12 KND95474.1 - 1.1 9.4 5.5 16 5.5 0.0 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Kelch_1 PF01344.25 KND95476.1 - 3.1e-09 36.3 0.0 3.2e-05 23.4 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 KND95476.1 - 3.4e-08 33.6 0.0 1.5e-06 28.3 0.0 3.3 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_4 PF13418.6 KND95476.1 - 9.4e-06 25.5 0.9 0.0026 17.7 0.1 3.9 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.6 KND95476.1 - 0.00018 21.7 0.4 0.0038 17.5 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.6 KND95476.1 - 0.0011 18.9 0.0 0.19 11.7 0.0 3.0 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.15 KND95476.1 - 0.0012 18.8 0.7 0.14 12.2 0.2 3.9 2 1 0 2 2 2 1 Kelch motif Ank_2 PF12796.7 KND95477.1 - 3.2e-10 40.5 0.1 1.8e-09 38.1 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) TIG PF01833.24 KND95477.1 - 5.1e-09 36.1 0.1 1.9e-08 34.2 0.1 2.0 2 0 0 2 2 2 1 IPT/TIG domain Ank_3 PF13606.6 KND95477.1 - 1.2e-06 28.4 0.1 0.067 13.8 0.1 3.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KND95477.1 - 1.5e-05 25.4 3.3 0.00012 22.6 0.1 3.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KND95477.1 - 3.8e-05 23.9 2.3 0.015 15.7 0.3 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KND95477.1 - 4.4e-05 23.7 0.0 0.001 19.3 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) RHD_dimer PF16179.5 KND95477.1 - 0.16 12.0 0.0 0.43 10.6 0.0 1.8 1 0 0 1 1 1 0 Rel homology dimerisation domain HEM4 PF02602.15 KND95478.1 - 8e-47 159.5 0.0 9.1e-47 159.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Antimicrobial17 PF08129.11 KND95478.1 - 0.16 12.0 0.0 0.66 10.0 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta enterocin family AMP-binding PF00501.28 KND95479.1 - 8.9e-89 298.0 0.0 1.1e-88 297.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KND95479.1 - 1.5e-23 83.5 0.1 2e-22 79.9 0.4 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KND95479.1 - 8.6e-17 60.8 0.2 2.5e-16 59.3 0.2 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus OPA3 PF07047.12 KND95483.1 - 8.4e-46 154.8 0.3 1.2e-45 154.3 0.3 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Phage_GP20 PF06810.11 KND95483.1 - 0.0015 18.4 1.7 0.0015 18.4 1.7 1.9 2 0 0 2 2 2 1 Phage minor structural protein GP20 S_4TM PF18159.1 KND95483.1 - 0.0022 17.4 0.1 0.004 16.5 0.1 1.3 1 0 0 1 1 1 1 SMODS-associating 4TM effector domain Striatin PF08232.12 KND95483.1 - 0.0048 17.5 0.4 0.0071 16.9 0.1 1.5 2 0 0 2 2 2 1 Striatin family DUF812 PF05667.11 KND95483.1 - 0.0057 15.6 0.7 0.0061 15.5 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) FmiP_Thoc5 PF09766.9 KND95483.1 - 0.0065 15.8 1.7 0.01 15.1 1.7 1.3 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 SKA2 PF16740.5 KND95483.1 - 0.01 15.6 0.4 0.018 14.8 0.4 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 LPP PF04728.13 KND95483.1 - 0.015 15.7 5.7 0.055 13.9 5.7 1.9 1 1 0 1 1 1 0 Lipoprotein leucine-zipper DUF4407 PF14362.6 KND95483.1 - 0.017 14.5 0.5 0.022 14.1 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Siah-Interact_N PF09032.11 KND95483.1 - 0.02 15.2 6.4 0.26 11.6 6.4 2.4 1 1 0 1 1 1 0 Siah interacting protein, N terminal DivIC PF04977.15 KND95483.1 - 0.021 14.6 3.1 0.021 14.6 1.7 1.8 2 0 0 2 2 2 0 Septum formation initiator ZapA PF05164.13 KND95483.1 - 0.035 14.5 0.5 0.35 11.3 0.5 2.1 1 1 0 1 1 1 0 Cell division protein ZapA DUF1664 PF07889.12 KND95483.1 - 0.1 12.6 1.9 0.2 11.7 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Spc24 PF08286.11 KND95483.1 - 0.11 12.7 3.2 0.24 11.6 3.2 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Spc7 PF08317.11 KND95483.1 - 0.14 11.0 3.7 0.2 10.5 3.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein GrpE PF01025.19 KND95483.1 - 0.19 11.4 5.1 0.31 10.7 5.1 1.3 1 0 0 1 1 1 0 GrpE Ly49 PF08391.10 KND95483.1 - 0.21 11.9 3.1 0.44 10.9 0.9 2.0 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region Fib_alpha PF08702.10 KND95483.1 - 0.27 11.4 3.8 0.16 12.2 1.6 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Histone PF00125.24 KND95484.1 - 5.3e-17 62.4 0.0 6.5e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KND95484.1 - 1e-13 50.7 1.2 1.7e-13 50.0 1.2 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KND95484.1 - 0.0012 19.1 0.0 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone NPR2 PF06218.11 KND95485.1 - 1.5e-181 604.0 2.1 3.1e-181 603.0 0.8 1.8 2 0 0 2 2 2 1 Nitrogen permease regulator 2 NPR3 PF03666.13 KND95485.1 - 0.048 12.5 0.0 0.048 12.5 0.0 2.9 2 1 1 4 4 4 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF89 PF01937.19 KND95486.1 - 2.6e-114 381.9 3.0 3e-114 381.7 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Zn_clus PF00172.18 KND95488.1 - 1.2e-10 41.3 9.1 2.5e-10 40.3 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND95488.1 - 5.5e-07 28.9 0.1 1.1e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cpn60_TCP1 PF00118.24 KND95489.1 - 2.8e-84 283.5 11.7 4.6e-84 282.8 11.7 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rrf2 PF02082.20 KND95489.1 - 0.012 15.9 0.1 0.033 14.5 0.1 1.8 1 0 0 1 1 1 0 Transcriptional regulator RNA_pol_I_TF PF04090.12 KND95490.1 - 1.2e-50 171.8 0.4 2.3e-50 170.9 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase I specific initiation factor zf-BED PF02892.15 KND95490.1 - 4.8e-06 26.5 0.5 4.8e-06 26.5 0.5 1.9 2 0 0 2 2 2 1 BED zinc finger zf-rbx1 PF12678.7 KND95491.1 - 5.9e-08 32.9 5.3 9.9e-08 32.2 5.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KND95491.1 - 6.4e-07 29.6 8.1 2e-06 28.0 8.1 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KND95491.1 - 0.00018 21.3 4.0 0.00063 19.5 0.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KND95491.1 - 0.00022 20.8 0.4 0.00045 19.8 0.4 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 KND95491.1 - 0.00037 20.3 4.8 0.00066 19.5 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KND95491.1 - 0.00041 20.2 3.1 0.00095 19.1 3.0 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KND95491.1 - 0.00049 19.9 2.4 0.00049 19.9 2.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KND95491.1 - 0.00069 19.4 2.1 0.0015 18.3 2.1 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KND95491.1 - 0.014 15.4 4.1 0.044 13.8 4.1 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KND95491.1 - 0.017 15.1 3.5 0.035 14.1 3.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KND95491.1 - 0.054 13.7 3.8 0.059 13.5 0.3 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KND95491.1 - 0.13 12.4 2.1 0.61 10.3 2.1 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KND95491.1 - 0.9 9.9 3.1 0.48 10.8 1.0 1.6 2 0 0 2 2 1 0 RING-like domain Kinesin PF00225.23 KND95492.1 - 3.2e-91 305.7 0.0 3.2e-91 305.7 0.0 2.3 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KND95492.1 - 6.2e-18 65.2 2.2 1.2e-17 64.2 0.0 2.6 3 1 0 3 3 3 1 Microtubule binding GM_CSF PF01109.17 KND95492.1 - 0.012 15.8 2.2 0.018 15.2 0.3 2.3 2 0 0 2 2 2 0 Granulocyte-macrophage colony-stimulating factor Phage_fiber_2 PF03406.13 KND95492.1 - 0.17 11.5 3.8 0.15 11.7 0.2 2.7 3 0 0 3 3 3 0 Phage tail fibre repeat HsbA PF12296.8 KND95492.1 - 0.32 11.4 11.6 0.41 11.1 3.4 3.7 3 0 0 3 3 3 0 Hydrophobic surface binding protein A PKcGMP_CC PF16808.5 KND95492.1 - 0.39 10.6 12.0 0.064 13.1 0.7 4.0 3 1 1 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Baculo_PEP_C PF04513.12 KND95492.1 - 0.9 9.6 24.5 0.13 12.3 3.8 3.8 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 KND95492.1 - 1.7 8.5 21.5 1.6 8.6 9.2 3.7 2 2 0 2 2 2 0 Apolipoprotein A1/A4/E domain Phage_Mu_F PF04233.14 KND95492.1 - 4.4 8.1 5.1 1 10.1 0.3 2.5 3 0 0 3 3 3 0 Phage Mu protein F like protein dsDNA_bind PF01984.20 KND95493.1 - 2.1e-25 89.1 8.4 5.5e-25 87.8 8.4 1.6 1 1 0 1 1 1 1 Double-stranded DNA-binding domain Ras PF00071.22 KND95494.1 - 1e-43 148.7 0.1 1.3e-43 148.4 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND95494.1 - 3.4e-25 88.6 0.2 7.7e-25 87.4 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND95494.1 - 2e-07 30.6 0.1 2.5e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KND95494.1 - 0.0014 18.2 0.1 0.0017 18.0 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain TIR_2 PF13676.6 KND95494.1 - 0.034 14.7 0.1 0.063 13.9 0.1 1.4 1 0 0 1 1 1 0 TIR domain LSM PF01423.22 KND95500.1 - 1.2e-08 34.5 0.3 1.5e-08 34.2 0.3 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KND95500.1 - 0.13 12.4 0.0 0.16 12.1 0.0 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain DUF727 PF05303.12 KND95501.1 - 4.7e-08 33.0 0.1 8.4e-06 25.8 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF727) WBS_methylT PF12589.8 KND95503.1 - 1.7e-12 47.9 6.3 2.7e-12 47.3 6.3 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KND95503.1 - 4.2e-12 46.6 0.0 7.7e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND95503.1 - 2.2e-11 44.3 0.0 5.4e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND95503.1 - 3.7e-07 30.8 0.0 9.5e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND95503.1 - 1e-05 25.4 0.0 1.8e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND95503.1 - 5.9e-05 22.9 0.0 0.00012 21.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 KND95503.1 - 0.0011 19.3 0.0 0.0021 18.4 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase CMAS PF02353.20 KND95503.1 - 0.0033 16.8 0.0 0.013 14.8 0.0 1.9 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase YkyA PF10368.9 KND95503.1 - 0.026 14.2 1.5 0.039 13.6 1.5 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein PCMT PF01135.19 KND95503.1 - 0.057 13.2 0.0 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KND95503.1 - 0.093 12.1 0.1 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KND95503.1 - 0.1 12.6 0.2 1 9.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KND95503.1 - 0.11 12.0 0.2 1.4 8.5 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase small domain N6_N4_Mtase PF01555.18 KND95503.1 - 0.11 12.2 0.1 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 DNA methylase MBOAT PF03062.19 KND95504.1 - 1.3e-39 136.6 31.5 1.7e-38 132.9 31.5 2.3 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KND95504.1 - 0.00063 20.0 3.2 0.0029 17.8 3.2 2.2 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family RAP80_UIM PF18282.1 KND95504.1 - 0.0085 15.9 0.3 0.019 14.7 0.3 1.5 1 0 0 1 1 1 1 RAP80 N-terminal ubiquitin interaction motif Peptidase_M76 PF09768.9 KND95505.1 - 1.4e-69 233.3 0.5 1.7e-69 233.0 0.5 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 KND95505.1 - 0.0012 18.6 0.2 0.0019 18.0 0.2 1.4 1 0 0 1 1 1 1 SprT-like family BSP PF04450.12 KND95505.1 - 0.018 14.8 0.0 0.048 13.4 0.0 1.7 2 0 0 2 2 2 0 Peptidase of plants and bacteria Tox-MPTase2 PF15638.6 KND95505.1 - 0.049 13.4 0.1 0.064 13.0 0.1 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 2 Peptidase_M91 PF14891.6 KND95505.1 - 0.052 13.9 0.1 0.083 13.2 0.1 1.3 1 1 0 1 1 1 0 Effector protein Ank_5 PF13857.6 KND95506.1 - 1.3e-18 66.8 0.0 3.9e-15 55.7 0.0 2.5 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KND95506.1 - 7.2e-15 55.1 0.1 2.1e-10 40.9 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KND95506.1 - 1.6e-13 51.1 0.0 1.1e-11 45.2 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KND95506.1 - 4e-11 42.8 0.1 4.4e-07 30.1 0.3 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KND95506.1 - 4.6e-10 38.8 0.2 1.5e-06 28.1 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeat tRNA_anti-like PF12869.7 KND95506.1 - 0.18 11.4 0.1 0.34 10.5 0.1 1.4 1 0 0 1 1 1 0 tRNA_anti-like DUF533 PF04391.12 KND95506.1 - 0.25 10.9 2.4 9.8 5.7 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF533) DUF1682 PF07946.14 KND95507.1 - 1.7e-90 303.6 7.8 1.9e-90 303.4 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Mitofilin PF09731.9 KND95507.1 - 0.0015 17.4 13.1 0.002 17.1 13.1 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF3692 PF12469.8 KND95507.1 - 0.035 14.3 0.1 0.25 11.6 0.0 2.1 2 0 0 2 2 2 0 CRISPR-associated protein PIEZO PF15917.5 KND95507.1 - 0.054 13.0 12.4 0.079 12.4 12.4 1.2 1 0 0 1 1 1 0 Piezo Stk19 PF10494.9 KND95508.1 - 2.2e-68 230.6 0.3 6.8e-67 225.7 0.1 2.0 2 0 0 2 2 2 2 Serine-threonine protein kinase 19 Mating_N PF12731.7 KND95508.1 - 0.0089 16.1 0.9 0.022 14.9 0.9 1.6 1 0 0 1 1 1 1 Mating-type protein beta 1 S_100 PF01023.19 KND95508.1 - 0.25 11.1 2.4 0.84 9.4 2.4 1.8 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Ribosomal_L9_N PF01281.19 KND95509.1 - 1.9e-07 30.6 0.0 4.6e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain PAG PF15347.6 KND95509.1 - 0.024 13.7 0.9 0.031 13.3 0.9 1.1 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched zf-HIT PF04438.16 KND95511.1 - 1.8e-09 37.3 6.5 2.9e-09 36.6 6.5 1.3 1 0 0 1 1 1 1 HIT zinc finger CDC45 PF02724.14 KND95511.1 - 0.28 9.4 6.0 0.37 9.0 6.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Tnp_zf-ribbon_2 PF13842.6 KND95511.1 - 0.71 10.7 8.2 1.6 9.6 8.2 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon AF-4 PF05110.13 KND95511.1 - 1.7 6.6 16.1 2.8 5.9 16.1 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RRM_1 PF00076.22 KND95512.1 - 1.1e-35 121.2 0.1 5.1e-18 64.7 0.2 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KND95512.1 - 0.0031 17.1 0.0 0.07 12.7 0.0 2.1 1 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 KND95512.1 - 0.0052 16.4 0.8 0.63 9.8 0.0 2.9 3 0 0 3 3 3 1 Ribonuclease B OB domain RRM_7 PF16367.5 KND95512.1 - 0.087 12.9 0.0 0.74 10.0 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif Nup35_RRM PF05172.13 KND95512.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif CBS PF00571.28 KND95513.1 - 3.3e-15 56.3 0.0 5e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 CBS domain Rep_Org_C PF06926.11 KND95513.1 - 0.13 12.6 0.4 0.77 10.1 0.4 2.0 1 1 1 2 2 2 0 Putative replisome organiser protein C-terminus Cyt-b5 PF00173.28 KND95514.1 - 1.3e-13 50.9 0.0 2.5e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 KND95514.1 - 1.1e-12 48.4 14.5 1.1e-12 48.4 14.5 1.5 1 1 0 1 1 1 1 Fatty acid desaturase SWIB PF02201.18 KND95515.1 - 1.1e-09 38.0 1.8 0.00023 21.0 0.1 2.6 2 0 0 2 2 2 2 SWIB/MDM2 domain SPOC PF07744.13 KND95515.1 - 0.05 13.5 0.0 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 SPOC domain WHIM1 PF15612.6 KND95516.1 - 0.0017 17.8 0.1 0.0049 16.4 0.1 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Ras PF00071.22 KND95518.1 - 6.7e-49 165.6 0.0 8.2e-49 165.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND95518.1 - 2.5e-29 101.9 0.0 6e-29 100.7 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND95518.1 - 1.4e-10 40.9 0.0 1.9e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KND95518.1 - 0.00062 19.8 0.0 0.0014 18.7 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KND95518.1 - 0.00075 19.9 0.0 0.0041 17.5 0.0 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 KND95518.1 - 0.0013 18.1 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.12 KND95518.1 - 0.022 14.2 0.1 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.20 KND95518.1 - 0.023 13.9 1.1 1.5 7.9 0.1 2.6 2 1 1 3 3 3 0 G-protein alpha subunit RsgA_GTPase PF03193.16 KND95518.1 - 0.032 14.1 0.1 6.6 6.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 KND95518.1 - 0.037 13.5 0.1 0.065 12.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KND95518.1 - 0.046 13.4 0.1 0.079 12.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KND95518.1 - 0.09 12.8 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KND95518.1 - 0.099 12.8 0.2 0.22 11.7 0.2 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KND95518.1 - 0.13 11.5 0.1 0.25 10.6 0.0 1.5 2 0 0 2 2 2 0 Septin AAA_16 PF13191.6 KND95518.1 - 0.14 12.6 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 KND95518.1 - 0.15 11.4 0.0 0.25 10.8 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit zf-U1 PF06220.12 KND95519.1 - 0.026 14.3 6.1 0.1 12.4 6.1 1.9 1 1 0 1 1 1 0 U1 zinc finger ATP_sub_h PF10775.9 KND95520.1 - 0.0014 18.6 0.7 0.0021 18.0 0.7 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ADIP PF11559.8 KND95521.1 - 2.7e-28 99.0 13.5 2.7e-28 99.0 13.5 3.0 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding FAM76 PF16046.5 KND95521.1 - 0.0045 16.4 4.9 0.0045 16.4 4.9 2.1 2 1 0 2 2 2 1 FAM76 protein ApoLp-III PF07464.11 KND95521.1 - 0.056 13.5 12.8 0.68 10.0 0.1 4.4 3 2 2 5 5 5 0 Apolipophorin-III precursor (apoLp-III) DUF5082 PF16888.5 KND95521.1 - 0.13 12.6 23.1 0.36 11.1 7.2 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF5082) BLOC1_2 PF10046.9 KND95521.1 - 0.34 11.2 24.1 0.24 11.7 3.2 4.3 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2935 PF11155.8 KND95521.1 - 0.6 10.5 7.3 8.4 6.7 0.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) ArdA PF07275.11 KND95521.1 - 1 9.9 4.1 0.95 10.0 0.5 2.5 2 1 1 3 3 3 0 Antirestriction protein (ArdA) Syntaxin-6_N PF09177.11 KND95521.1 - 1 9.9 18.6 13 6.4 0.0 4.3 2 1 0 3 3 3 0 Syntaxin 6, N-terminal DUF4200 PF13863.6 KND95521.1 - 2.1 8.8 25.7 2.7 8.4 1.1 4.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4200) DASH_Dad1 PF08649.10 KND95521.1 - 2.1 8.6 5.3 7.2 6.9 0.9 3.0 2 0 0 2 2 2 0 DASH complex subunit Dad1 SlyX PF04102.12 KND95521.1 - 2.5 8.8 19.5 12 6.6 1.8 5.3 3 2 3 6 6 6 0 SlyX APG6_N PF17675.1 KND95521.1 - 3 8.4 26.5 3.9 8.0 7.9 3.3 2 1 1 3 3 3 0 Apg6 coiled-coil region DUF948 PF06103.11 KND95521.1 - 3.7 7.9 5.7 13 6.1 1.9 3.2 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4795 PF16043.5 KND95521.1 - 4.4 6.9 23.2 5.2 6.6 2.0 3.5 2 2 0 2 2 2 0 Domain of unknown function (DUF4795) Peptidase_S76 PF13611.6 KND95522.1 - 0.018 15.4 0.7 0.033 14.5 0.7 1.4 1 0 0 1 1 1 0 Serine peptidase of plant viral polyprotein, P1 DUF4446 PF14584.6 KND95522.1 - 0.095 12.7 0.7 0.17 11.8 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) EphA2_TM PF14575.6 KND95522.1 - 0.18 12.7 0.4 40 5.2 0.0 2.7 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain MCM PF00493.23 KND95523.1 - 4.1e-103 343.3 0.0 6.3e-103 342.7 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KND95523.1 - 5.8e-37 126.4 0.4 1e-36 125.5 0.4 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KND95523.1 - 5.9e-25 87.5 1.1 1.7e-24 86.1 1.1 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KND95523.1 - 1.1e-15 58.1 0.5 2.9e-15 56.7 0.5 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KND95523.1 - 1.6e-06 27.7 0.0 0.00068 19.1 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KND95523.1 - 1.2e-05 25.3 0.0 3.6e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KND95523.1 - 0.0012 18.7 0.2 0.0055 16.6 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KND95523.1 - 0.029 14.1 0.0 0.42 10.3 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 KND95523.1 - 0.066 13.6 0.0 0.22 11.9 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 KND95523.1 - 0.09 12.9 0.1 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Prefoldin PF02996.17 KND95524.1 - 1.8e-27 95.6 5.8 2e-27 95.5 5.8 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KND95524.1 - 0.022 14.7 8.9 0.018 15.0 4.2 2.1 1 1 1 2 2 2 0 Prefoldin subunit Tsi6 PF18660.1 KND95524.1 - 0.029 14.4 0.1 0.063 13.3 0.1 1.6 1 0 0 1 1 1 0 Tsi6 End3 PF12761.7 KND95524.1 - 0.065 13.4 7.1 0.099 12.8 0.5 2.1 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Syntaxin-6_N PF09177.11 KND95524.1 - 0.52 10.9 6.1 5.8 7.5 6.1 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF5510 PF17629.2 KND95525.1 - 0.043 13.7 0.2 0.16 11.9 0.2 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5510) Ribosomal_L18 PF17135.4 KND95526.1 - 8.1e-71 237.3 2.7 9.3e-71 237.1 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KND95526.1 - 0.0015 19.2 0.4 0.0034 18.0 0.4 1.7 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A AAA_6 PF12774.7 KND95527.1 - 8.6e-103 343.7 0.1 1.7e-101 339.5 0.0 3.0 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KND95527.1 - 2.6e-86 290.2 8.4 2.6e-86 290.2 8.4 4.7 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KND95527.1 - 3.1e-50 170.9 3.6 1.5e-49 168.7 0.0 3.5 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KND95527.1 - 3.7e-45 153.8 0.1 3.7e-45 153.8 0.1 5.3 7 0 0 7 7 6 1 ATP-binding dynein motor region AAA_7 PF12775.7 KND95527.1 - 5e-44 150.0 0.2 1.8e-36 125.4 0.0 5.2 5 0 0 5 5 5 2 P-loop containing dynein motor region DHC_N1 PF08385.12 KND95527.1 - 3.1e-34 118.5 16.2 3.1e-34 118.5 16.2 3.0 3 1 1 4 4 4 1 Dynein heavy chain, N-terminal region 1 MT PF12777.7 KND95527.1 - 3.9e-27 95.2 7.5 6.6e-27 94.4 7.5 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 KND95527.1 - 2.7e-25 88.9 0.0 1.3e-10 41.4 0.0 6.1 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 KND95527.1 - 1.3e-22 80.4 0.0 3.8e-22 78.9 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KND95527.1 - 1.7e-16 60.9 6.7 1.3e-05 25.7 0.0 6.7 7 0 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 KND95527.1 - 2.6e-16 59.8 0.1 4.4e-14 52.6 0.2 3.9 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 KND95527.1 - 2.2e-13 50.6 3.6 0.0044 17.3 0.0 7.1 6 1 0 6 6 5 4 AAA domain Dynein_AAA_lid PF17852.1 KND95527.1 - 4.1e-09 36.6 0.2 4.1e-09 36.6 0.2 3.5 4 0 0 4 4 2 1 Dynein heavy chain AAA lid domain T2SSE PF00437.20 KND95527.1 - 1.4e-08 34.2 0.0 0.29 10.2 0.0 3.8 3 0 0 3 3 3 3 Type II/IV secretion system protein AAA_18 PF13238.6 KND95527.1 - 2.5e-08 34.5 0.2 2.2 8.9 0.0 5.8 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 KND95527.1 - 1.8e-07 31.7 0.0 1 9.7 0.0 5.8 4 0 0 4 4 4 1 AAA ATPase domain AAA_lid_1 PF17857.1 KND95527.1 - 9.2e-07 29.0 0.2 9.7e-06 25.7 0.0 2.9 2 0 0 2 2 1 1 AAA+ lid domain TsaE PF02367.17 KND95527.1 - 6.1e-05 23.0 2.5 0.14 12.2 0.1 4.2 4 0 0 4 4 4 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KND95527.1 - 6.3e-05 23.2 6.8 2 8.6 0.0 6.2 6 0 0 6 6 6 1 AAA domain AAA_29 PF13555.6 KND95527.1 - 0.00012 21.7 0.1 0.57 10.0 0.1 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KND95527.1 - 0.00028 20.7 2.2 12 5.6 0.7 4.8 4 1 0 4 4 4 0 AAA domain AAA_25 PF13481.6 KND95527.1 - 0.0012 18.5 0.3 0.11 12.0 0.0 3.7 4 0 0 4 4 3 1 AAA domain FtsK_SpoIIIE PF01580.18 KND95527.1 - 0.0024 17.3 0.3 4.1 6.7 0.0 3.9 4 0 0 4 4 3 1 FtsK/SpoIIIE family BRE1 PF08647.11 KND95527.1 - 0.0031 17.5 6.5 0.0031 17.5 6.5 4.3 4 0 0 4 4 2 1 BRE1 E3 ubiquitin ligase Zeta_toxin PF06414.12 KND95527.1 - 0.0046 16.3 0.5 6.5 6.0 0.0 3.7 3 0 0 3 3 3 0 Zeta toxin cobW PF02492.19 KND95527.1 - 0.0076 15.9 2.0 0.38 10.3 0.2 3.2 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 KND95527.1 - 0.0095 16.3 7.1 3.7 7.9 0.0 5.4 5 0 0 5 5 5 1 AAA domain NACHT PF05729.12 KND95527.1 - 0.011 15.6 6.1 0.077 12.9 0.0 4.3 5 0 0 5 5 3 0 NACHT domain Mg_chelatase PF01078.21 KND95527.1 - 0.022 14.1 6.0 1.2 8.5 0.0 4.1 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KND95527.1 - 0.025 14.3 3.7 23 4.6 0.0 4.9 5 0 0 5 5 5 0 AAA domain RuvB_N PF05496.12 KND95527.1 - 0.033 13.9 0.3 0.4 10.4 0.0 2.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KND95527.1 - 0.036 13.8 3.2 2.9 7.6 0.0 4.7 5 0 0 5 5 5 0 IstB-like ATP binding protein AAA_lid_7 PF17867.1 KND95527.1 - 0.037 14.2 0.2 0.45 10.7 0.1 3.0 2 0 0 2 2 2 0 Midasin AAA lid domain NTPase_1 PF03266.15 KND95527.1 - 0.055 13.4 0.5 21 5.0 0.0 4.0 3 0 0 3 3 3 0 NTPase ResIII PF04851.15 KND95527.1 - 0.057 13.4 1.3 7.6 6.5 0.0 4.3 4 2 0 4 4 4 0 Type III restriction enzyme, res subunit Roc PF08477.13 KND95527.1 - 0.071 13.3 0.4 3.8 7.7 0.1 3.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 KND95527.1 - 0.073 13.3 1.1 38 4.5 0.0 4.4 4 0 0 4 4 3 0 AAA domain PduV-EutP PF10662.9 KND95527.1 - 0.19 11.4 1.6 8.5 6.1 0.1 3.3 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 KND95527.1 - 0.48 10.9 9.9 2.4 8.7 0.0 5.0 5 0 0 5 5 3 0 ABC transporter SMC_N PF02463.19 KND95527.1 - 7 6.0 6.1 43 3.4 0.0 4.1 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain DUF1664 PF07889.12 KND95527.1 - 7.2 6.7 18.3 25 4.9 0.8 4.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Mpv17_PMP22 PF04117.12 KND95528.1 - 2.5e-18 66.0 6.1 7e-18 64.6 6.0 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.12 KND95529.1 - 2.1e-25 88.7 5.9 3.6e-25 87.9 5.9 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family TetR_C_20 PF17925.1 KND95529.1 - 0.083 13.2 0.1 1 9.7 0.1 2.2 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain B56 PF01603.20 KND95531.1 - 3.5e-173 576.4 17.1 2.5e-162 540.6 12.3 2.1 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) TetR_C_2 PF08361.11 KND95531.1 - 0.036 14.2 0.0 0.13 12.4 0.0 1.9 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region Sec7_N PF12783.7 KND95531.1 - 0.074 12.9 4.0 1.6 8.6 0.3 2.6 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal IMPDH PF00478.25 KND95532.1 - 1.7e-31 109.5 0.0 1.8e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KND95532.1 - 0.052 12.9 0.0 0.067 12.6 0.0 1.1 1 0 0 1 1 1 0 Nitronate monooxygenase Repressor_Mnt PF11423.8 KND95532.1 - 0.097 12.5 0.2 0.23 11.3 0.2 1.6 1 0 0 1 1 1 0 Regulatory protein Mnt IMPDH PF00478.25 KND95533.1 - 6.7e-100 334.4 0.2 7.7e-100 334.2 0.2 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KND95533.1 - 1.5e-07 30.8 4.5 8e-07 28.4 4.3 2.1 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 KND95533.1 - 1.2e-05 24.9 0.7 2.5e-05 23.9 0.7 1.5 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 KND95533.1 - 9.6e-05 21.9 0.5 0.00061 19.3 0.5 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 KND95533.1 - 0.0001 21.7 1.3 0.00029 20.2 0.4 1.9 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG NanE PF04131.14 KND95533.1 - 0.0025 17.0 0.0 0.0053 16.0 0.0 1.5 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase CBS PF00571.28 KND95533.1 - 0.01 16.3 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 0 CBS domain Aldolase PF01081.19 KND95533.1 - 0.022 14.2 0.2 0.077 12.4 0.0 1.9 3 0 0 3 3 3 0 KDPG and KHG aldolase EAL PF00563.20 KND95533.1 - 0.051 13.1 0.0 8.4 5.8 0.0 2.5 2 0 0 2 2 2 0 EAL domain Radical_SAM PF04055.21 KND95533.1 - 0.19 12.1 0.0 2.8 8.3 0.0 2.2 1 1 1 2 2 2 0 Radical SAM superfamily CH PF00307.31 KND95534.1 - 3.7e-15 56.0 0.0 4.9e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF1322 PF07032.11 KND95535.1 - 0.019 15.5 0.0 0.026 15.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1322) Ribosomal_L28e PF01778.17 KND95536.1 - 2.3e-36 125.0 0.6 2.3e-36 125.0 0.6 1.8 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 KND95536.1 - 6.6e-31 106.9 12.9 6.6e-31 106.9 12.9 2.7 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 KND95536.1 - 0.00033 20.1 15.9 0.0004 19.9 15.9 1.1 1 0 0 1 1 1 1 BUD22 Ribosomal_L24e PF01246.20 KND95536.1 - 0.0081 16.4 0.1 0.02 15.1 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e PYC_OADA PF02436.18 KND95536.1 - 0.061 13.1 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Conserved carboxylase domain Nop14 PF04147.12 KND95536.1 - 4.5 5.4 23.5 5.9 5.0 23.5 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 KND95536.1 - 6.6 5.2 27.1 8.7 4.8 27.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RTA1 PF04479.13 KND95537.1 - 1.9e-65 220.3 11.5 3.5e-65 219.5 9.0 2.1 2 0 0 2 2 2 1 RTA1 like protein ERGIC_N PF13850.6 KND95537.1 - 0.05 14.0 0.5 0.35 11.3 0.0 2.4 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) COX7B PF05392.11 KND95537.1 - 0.14 11.8 0.7 0.65 9.7 0.7 2.1 1 1 0 1 1 1 0 Cytochrome C oxidase chain VIIB KilA-N PF04383.13 KND95538.1 - 0.00039 20.3 0.0 0.026 14.4 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain Auxin_repressed PF05564.12 KND95538.1 - 0.033 14.9 0.2 0.058 14.1 0.2 1.4 1 0 0 1 1 1 0 Dormancy/auxin associated protein Period_C PF12114.8 KND95538.1 - 0.042 13.4 4.4 0.061 12.9 4.4 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Aa_trans PF01490.18 KND95540.1 - 1.1e-51 175.9 31.9 1.3e-51 175.7 31.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SH3_13 PF18335.1 KND95541.1 - 0.051 13.4 0.0 0.067 13.0 0.0 1.2 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain RRM_1 PF00076.22 KND95542.1 - 2.9e-13 49.4 2.2 0.00012 21.9 0.1 4.5 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DDE_3 PF13358.6 KND95542.1 - 0.03 14.1 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease STAT1_TAZ2bind PF12162.8 KND95542.1 - 3.5 7.3 6.7 38 4.0 0.2 3.4 3 0 0 3 3 3 0 STAT1 TAZ2 binding domain Shisa PF13908.6 KND95542.1 - 7.6 6.7 5.7 22 5.2 0.4 3.1 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Sugar_tr PF00083.24 KND95543.1 - 6.4e-86 289.0 20.5 7.5e-86 288.8 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND95543.1 - 1.2e-27 96.8 30.6 4.5e-24 85.0 22.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.6 KND95543.1 - 2 8.0 0.0 2 8.0 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) HpaB PF03241.13 KND95544.1 - 0.11 11.5 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Glyco_hydro_3_C PF01915.22 KND95546.1 - 4.3e-52 177.0 0.0 6.5e-52 176.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KND95546.1 - 5.5e-36 124.5 0.0 8.6e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KND95546.1 - 2e-19 69.5 0.2 4.6e-19 68.3 0.2 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KND95546.1 - 0.00039 20.2 0.2 0.0015 18.4 0.0 1.9 2 0 0 2 2 2 1 PA14 domain Pertussis_S2S3 PF02918.15 KND95546.1 - 0.063 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain FMN_dh PF01070.18 KND95549.1 - 3.2e-111 371.7 0.0 3.8e-111 371.5 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KND95549.1 - 4.4e-23 81.2 0.0 8.9e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KND95549.1 - 2.3e-10 40.2 0.2 3.5e-10 39.6 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KND95549.1 - 0.0001 21.8 0.2 0.00016 21.2 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KND95549.1 - 0.00011 21.3 0.8 0.00023 20.3 0.0 1.8 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KND95549.1 - 0.00027 20.5 0.2 0.5 9.8 0.1 2.4 2 0 0 2 2 2 2 Histidine biosynthesis protein Peptidase_M19 PF01244.21 KND95549.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) ThiG PF05690.14 KND95549.1 - 0.14 11.5 1.5 8.1 5.7 0.1 2.5 1 1 2 3 3 3 0 Thiazole biosynthesis protein ThiG DUF5314 PF17241.2 KND95552.1 - 0.0019 17.9 0.1 0.0022 17.7 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5314) UDPGP PF01704.18 KND95554.1 - 8.3e-190 630.8 0.0 9.5e-190 630.6 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NAPRTase PF04095.16 KND95556.1 - 3.8e-65 219.9 0.0 4.9e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KND95556.1 - 1.7e-35 122.2 0.2 3.1e-35 121.3 0.2 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain IBN_N PF03810.19 KND95557.1 - 1.8e-17 63.0 0.3 1.2e-16 60.3 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KND95557.1 - 0.0079 16.3 0.2 0.0079 16.3 0.2 3.6 5 1 0 5 5 5 1 Exportin 1-like protein CtaG_Cox11 PF04442.14 KND95558.1 - 7.1e-52 175.4 0.4 8.6e-52 175.2 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 PPTA PF01239.22 KND95559.1 - 2e-29 100.4 14.5 8.4e-09 34.9 0.2 4.7 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat DUF3950 PF13132.6 KND95559.1 - 0.11 12.2 2.0 3.7 7.4 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3950) GST_N PF02798.20 KND95560.1 - 1.7e-10 41.1 0.0 3.1e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KND95560.1 - 1.1e-09 38.4 0.0 3.1e-09 36.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KND95560.1 - 2e-09 37.6 0.1 3.8e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KND95560.1 - 2.3e-08 34.3 0.1 6.7e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KND95560.1 - 4.3e-07 30.1 0.0 8.7e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KND95560.1 - 3.7e-06 26.9 0.0 6.6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KND95560.1 - 0.09 13.5 0.0 0.19 12.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain TauD PF02668.16 KND95561.1 - 7.3e-56 189.9 0.7 1.3e-55 189.1 0.7 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_transf_15 PF01793.16 KND95562.1 - 3.4e-120 401.2 15.3 4.6e-120 400.8 15.3 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase OPT PF03169.15 KND95563.1 - 8.1e-126 421.1 46.0 9.2e-126 420.9 46.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein tRNA-synt_2 PF00152.20 KND95564.1 - 1.5e-100 336.3 0.0 2e-100 335.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KND95564.1 - 7.5e-05 22.6 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KND95564.1 - 0.0016 18.0 0.1 0.0079 15.7 0.1 2.0 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) PUF PF00806.19 KND95565.1 - 6.9e-24 82.2 0.1 0.00025 20.6 0.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat GST_C PF00043.25 KND95566.1 - 4.4e-11 42.8 0.0 3.1e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KND95566.1 - 1.7e-08 34.6 0.0 3.5e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KND95566.1 - 1.2e-05 25.2 0.1 4.2e-05 23.5 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PIN_6 PF17146.4 KND95567.1 - 3.1e-29 101.3 0.0 8.9e-29 99.8 0.0 1.8 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 KND95567.1 - 1.4e-26 92.4 1.7 2.6e-26 91.6 1.7 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Zn-ribbon_8 PF09723.10 KND95567.1 - 0.0013 18.8 2.9 0.0027 17.8 2.9 1.5 1 0 0 1 1 1 1 Zinc ribbon domain WRNPLPNID PF15017.6 KND95567.1 - 1.9 9.4 17.0 2.3 9.1 8.8 2.9 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box EF-hand_4 PF12763.7 KND95568.1 - 5.5e-05 23.1 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Dfp1_Him1_M PF08630.10 KND95568.1 - 0.066 13.4 0.7 0.24 11.6 0.1 2.2 2 0 0 2 2 2 0 Dfp1/Him1, central region EF-hand_8 PF13833.6 KND95568.1 - 0.092 12.6 0.0 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain pair Ribosomal_L12 PF00542.19 KND95568.1 - 0.12 12.7 1.1 0.3 11.4 1.1 1.7 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain EF-hand_1 PF00036.32 KND95568.1 - 0.21 11.2 0.0 0.51 10.0 0.0 1.7 1 0 0 1 1 1 0 EF hand HDA2-3 PF11496.8 KND95569.1 - 9.3e-52 176.0 1.7 9.3e-52 176.0 1.7 1.8 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 HSP70 PF00012.20 KND95569.1 - 0.25 9.5 10.0 0.47 8.6 10.0 1.4 1 0 0 1 1 1 0 Hsp70 protein V_ATPase_I PF01496.19 KND95569.1 - 0.26 9.1 7.5 0.44 8.4 7.5 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4972 PF16342.5 KND95569.1 - 0.52 10.0 7.2 0.67 9.6 5.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4972) PHM7_cyt PF14703.6 KND95569.1 - 0.74 10.0 9.2 0.51 10.6 6.7 2.1 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter TMEM192 PF14802.6 KND95569.1 - 0.82 8.7 3.0 1.3 8.0 3.0 1.3 1 0 0 1 1 1 0 TMEM192 family SlyX PF04102.12 KND95569.1 - 2.4 8.8 11.7 23 5.7 3.8 3.8 3 1 0 3 3 3 0 SlyX DUF745 PF05335.13 KND95569.1 - 3 7.5 13.8 4.4 7.0 13.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Fib_alpha PF08702.10 KND95569.1 - 5.4 7.2 8.5 19 5.4 8.5 2.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family LMBR1 PF04791.16 KND95569.1 - 6.3 5.6 8.8 4.8 6.0 6.4 1.9 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF948 PF06103.11 KND95569.1 - 6.5 7.1 7.9 26 5.2 1.6 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4164 PF13747.6 KND95569.1 - 7.9 6.8 18.2 1.4 9.2 4.4 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4164) Pyridoxal_deC PF00282.19 KND95570.1 - 5.4e-19 68.1 0.0 8.2e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 KND95570.1 - 1e-08 34.9 0.0 1.5e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KND95570.1 - 1.8e-07 30.4 0.0 1e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KND95570.1 - 9.1e-05 21.8 0.0 0.00013 21.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KND95570.1 - 0.0069 15.0 0.0 0.011 14.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Cadherin_C PF01049.17 KND95570.1 - 0.087 13.2 0.0 0.21 11.9 0.0 1.6 2 0 0 2 2 2 0 Cadherin cytoplasmic region PQ-loop PF04193.14 KND95572.1 - 3.3e-17 62.0 0.1 6.5e-17 61.1 0.1 1.5 1 0 0 1 1 1 1 PQ loop repeat MAP65_ASE1 PF03999.12 KND95574.1 - 1.7e-48 165.8 35.9 1.7e-48 165.8 35.9 2.3 2 1 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) MMR_HSR1 PF01926.23 KND95575.1 - 2.7e-17 62.9 0.1 8.5e-15 54.8 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KND95575.1 - 8.8e-07 28.6 0.3 9.1e-06 25.3 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KND95575.1 - 2.3e-06 27.6 2.2 0.0086 16.0 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase AIG1 PF04548.16 KND95575.1 - 0.0078 15.6 0.1 0.021 14.2 0.1 1.7 1 0 0 1 1 1 1 AIG1 family Arf PF00025.21 KND95575.1 - 0.019 14.4 1.1 0.019 14.4 1.1 2.7 3 0 0 3 3 3 0 ADP-ribosylation factor family cobW PF02492.19 KND95575.1 - 0.041 13.5 0.2 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KND95575.1 - 0.17 10.9 0.0 0.5 9.3 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 KND95575.1 - 1.4 9.3 3.8 26 5.2 0.1 3.0 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 KND95575.1 - 2.5 8.1 7.2 0.32 11.0 0.8 2.8 2 1 1 3 3 3 0 Dynamin family AA_permease PF00324.21 KND95579.1 - 2.1e-19 69.5 0.2 2.2e-19 69.4 0.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND95579.1 - 0.002 17.0 0.4 0.0021 17.0 0.4 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 KND95580.1 - 1.8e-07 30.5 39.1 6.9e-05 21.9 38.2 3.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Mlo PF03094.15 KND95580.1 - 0.016 13.6 0.5 0.03 12.7 0.1 1.6 1 1 0 1 1 1 0 Mlo family DUF2854 PF11016.8 KND95580.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) DUF4131 PF13567.6 KND95580.1 - 2.5 7.7 10.8 0.46 10.1 0.1 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF4131) FmdA_AmdA PF03069.15 KND95583.1 - 5e-168 558.7 0.0 5.7e-168 558.5 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family DUF2161 PF09929.9 KND95583.1 - 0.15 12.1 0.2 0.57 10.3 0.1 1.9 2 0 0 2 2 2 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) Toprim_4 PF13662.6 KND95584.1 - 0.04 14.4 0.1 0.05 14.1 0.1 1.2 1 0 0 1 1 1 0 Toprim domain Flocculin_t3 PF13928.6 KND95585.1 - 0.00069 20.1 28.7 0.0065 17.0 13.1 6.0 3 2 2 5 5 5 3 Flocculin type 3 repeat CFEM PF05730.11 KND95585.1 - 0.34 11.0 0.1 0.34 11.0 0.1 4.3 2 1 1 3 3 3 0 CFEM domain Transp_cyt_pur PF02133.15 KND95586.1 - 8e-67 225.9 33.2 9.9e-67 225.6 33.2 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF681 PF05080.12 KND95586.1 - 0.029 15.0 0.0 0.077 13.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF681) Peptidase_C14 PF00656.22 KND95588.1 - 3.9e-69 233.4 0.0 5.1e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain adh_short_C2 PF13561.6 KND95589.1 - 1.5e-41 142.5 0.9 1.7e-41 142.3 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND95589.1 - 1.1e-33 116.4 1.6 1.4e-33 116.0 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND95589.1 - 1.5e-10 41.3 0.6 2.3e-10 40.7 0.6 1.2 1 0 0 1 1 1 1 KR domain PDZ PF00595.24 KND95589.1 - 0.073 13.4 0.2 0.13 12.6 0.2 1.4 1 0 0 1 1 1 0 PDZ domain Sacchrp_dh_NADP PF03435.18 KND95589.1 - 0.077 13.3 0.2 0.12 12.7 0.2 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Glyco_tran_WecB PF03808.13 KND95589.1 - 0.077 12.9 0.1 1.7 8.6 0.1 2.2 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family DUF1977 PF09320.11 KND95591.1 - 2e-34 118.0 2.8 5e-34 116.7 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KND95591.1 - 5.3e-25 87.3 0.8 9.9e-25 86.5 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain DUF2427 PF10348.9 KND95591.1 - 0.082 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) DUF390 PF04094.14 KND95593.1 - 0.66 8.2 1.3 0.77 8.0 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Peptidase_S49_N PF08496.10 KND95593.1 - 0.84 9.7 3.4 1.3 9.1 3.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Asp PF00026.23 KND95594.1 - 2.2e-67 227.7 3.2 5.8e-60 203.4 0.8 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KND95594.1 - 2.9e-08 34.2 2.3 5.6e-07 30.0 0.4 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KND95594.1 - 0.00015 22.3 0.1 8.9 7.0 0.0 3.5 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KND95594.1 - 0.0028 18.2 0.0 2.9 8.5 0.0 3.6 4 0 0 4 4 4 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KND95594.1 - 0.074 12.8 0.0 0.54 10.0 0.0 2.1 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal HAMP PF00672.25 KND95596.1 - 1.9e-33 114.6 11.7 3.5e-09 36.9 0.8 6.6 6 0 0 6 6 6 5 HAMP domain HATPase_c PF02518.26 KND95596.1 - 1.6e-28 99.5 0.1 3.7e-28 98.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KND95596.1 - 4.7e-26 91.2 0.2 2e-25 89.2 0.2 2.2 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KND95596.1 - 3.2e-18 65.5 0.9 2.5e-17 62.6 0.7 2.8 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain DUF4279 PF14106.6 KND95596.1 - 0.017 15.3 0.1 4.7 7.4 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4279) IL32 PF15225.6 KND95596.1 - 0.15 12.5 0.1 61 4.1 0.0 3.6 3 0 0 3 3 3 0 Interleukin 32 DUF3829 PF12889.7 KND95596.1 - 0.99 8.8 14.1 1.7 8.0 0.1 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF3829) CENP-F_leu_zip PF10473.9 KND95596.1 - 8.2 6.5 13.1 6.9 6.7 0.0 5.4 6 0 0 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DNA_pol_B PF00136.21 KND95597.1 - 2.1e-151 504.7 3.3 2.9e-151 504.3 3.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KND95597.1 - 2.8e-84 283.1 0.4 4.6e-84 282.4 0.4 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KND95597.1 - 6.1e-18 65.1 11.0 1.5e-17 63.8 11.0 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 KND95597.1 - 0.0015 17.5 1.2 0.02 13.8 0.2 2.5 2 1 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 KND95597.1 - 0.011 15.7 0.4 0.2 11.6 0.1 3.0 2 1 0 2 2 2 0 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 KND95597.1 - 0.012 15.3 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Glycohydro_20b2 PF14845.6 KND95597.1 - 0.17 12.5 0.1 2.4 8.8 0.1 2.6 2 0 0 2 2 2 0 beta-acetyl hexosaminidase like Med5 PF08689.10 KND95598.1 - 8.6e-63 212.6 30.1 8.6e-63 212.6 30.1 2.2 2 1 0 2 2 2 1 Mediator complex subunit Med5 AbiJ_NTD3 PF18860.1 KND95598.1 - 0.025 14.1 0.4 0.42 10.1 0.2 2.7 2 0 0 2 2 2 0 AbiJ N-terminal domain 3 FAST_1 PF06743.15 KND95598.1 - 0.14 12.1 1.7 0.35 10.8 0.1 2.7 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 CDC24_OB3 PF17244.2 KND95599.1 - 3.4 7.3 6.6 0.68 9.6 2.0 1.9 1 1 0 2 2 2 0 Cell division control protein 24, OB domain 3 Pex14_N PF04695.13 KND95600.1 - 3.4e-36 125.3 0.7 3.4e-36 125.3 0.7 3.2 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CCDC84 PF14968.6 KND95600.1 - 0.0037 16.9 7.8 0.0037 16.9 7.8 1.6 3 0 0 3 3 3 1 Coiled coil protein 84 CBP_BcsO PF17037.5 KND95600.1 - 0.015 15.5 10.1 0.17 12.0 2.7 2.2 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsO Tup_N PF08581.10 KND95600.1 - 0.1 12.9 9.3 0.11 12.8 6.9 2.3 1 1 0 2 2 2 0 Tup N-terminal DUF1664 PF07889.12 KND95600.1 - 0.24 11.5 6.5 2.1 8.4 6.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FSA_C PF10479.9 KND95600.1 - 0.45 8.6 4.5 0.82 7.7 4.5 1.4 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SpmSyn_N PF17950.1 KND95600.1 - 0.63 10.3 3.4 15 5.9 0.2 2.4 2 0 0 2 2 2 0 S-adenosylmethionine decarboxylase N -terminal UPF0242 PF06785.11 KND95600.1 - 0.99 9.5 12.2 0.12 12.4 3.8 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus NPV_P10 PF05531.12 KND95600.1 - 3.3 8.2 11.7 3.4 8.2 0.7 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Mito_carr PF00153.27 KND95602.1 - 3.6e-44 148.6 1.9 2.5e-16 59.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Prenyltrans PF00432.21 KND95603.1 - 1.3e-23 82.5 0.5 1.3e-05 24.8 0.0 5.6 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat ACPS PF01648.20 KND95604.1 - 1.1e-09 38.4 0.0 2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Beta_elim_lyase PF01212.21 KND95605.1 - 6.5e-77 258.7 0.0 8.2e-77 258.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KND95605.1 - 1.3e-06 27.8 0.0 1.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aldedh PF00171.22 KND95607.1 - 5.6e-176 585.6 4.8 6.3e-176 585.4 4.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KND95607.1 - 3.9e-05 22.9 0.1 5.7e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 KND95607.1 - 0.0013 18.2 0.7 0.0068 15.9 0.7 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) MCM3AP_GANP PF16769.5 KND95607.1 - 0.049 11.9 0.0 0.068 11.4 0.0 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP F-box-like PF12937.7 KND95608.1 - 1.4e-05 24.8 0.2 5e-05 23.1 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KND95608.1 - 0.0024 17.7 0.3 0.014 15.2 0.0 2.4 2 0 0 2 2 2 1 F-box Vezatin PF12632.7 KND95611.1 - 2.9e-09 36.7 7.4 4.9e-09 36.0 6.9 1.7 1 1 0 1 1 1 1 Mysoin-binding motif of peroxisomes DNA_ligase_A_M PF01068.21 KND95611.1 - 0.17 11.5 1.1 0.9 9.1 0.2 2.3 2 1 1 3 3 3 0 ATP dependent DNA ligase domain SNF2_N PF00176.23 KND95612.1 - 5.3e-64 216.1 0.8 1e-63 215.2 0.8 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 KND95612.1 - 3.2e-47 160.3 18.6 3.2e-47 160.3 18.6 2.7 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.31 KND95612.1 - 2.7e-17 63.1 0.0 9.2e-17 61.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KND95612.1 - 1.4e-06 27.7 0.2 1.4e-06 27.7 0.2 3.7 3 2 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KND95612.1 - 4.3e-05 23.6 0.0 4.3e-05 23.6 0.0 3.0 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Fe_hyd_lg_C PF02906.14 KND95612.1 - 0.0042 16.8 0.2 0.0092 15.7 0.2 1.5 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DUF4393 PF14337.6 KND95612.1 - 0.042 13.7 5.6 0.1 12.4 2.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4393) Tmemb_14 PF03647.13 KND95614.1 - 8.2e-24 84.2 4.0 9.2e-24 84.0 4.0 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 KND95614.1 - 0.014 15.7 3.0 0.042 14.2 3.0 1.7 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 19 PEP-CTERM PF07589.11 KND95614.1 - 2.2 8.5 7.6 16 5.7 0.0 3.5 3 0 0 3 3 3 0 PEP-CTERM motif Ribosomal_S3_C PF00189.20 KND95616.1 - 3.6e-23 81.9 0.6 1.7e-22 79.7 0.5 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KND95616.1 - 9.1e-09 35.0 0.4 1.9e-08 34.0 0.4 1.6 1 0 0 1 1 1 1 KH domain GATase_5 PF13507.6 KND95617.1 - 1.1e-99 332.8 0.0 1.7e-99 332.2 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KND95617.1 - 5.8e-41 140.2 2.1 1.1e-28 100.3 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KND95617.1 - 4e-24 84.8 0.0 7.7e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KND95617.1 - 6.9e-22 77.7 0.0 1.7e-21 76.5 0.0 1.8 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain HV_small_capsid PF17086.5 KND95617.1 - 0.071 13.4 0.1 0.19 12.1 0.1 1.7 1 0 0 1 1 1 0 Small capsid protein of Herpesviridae Synaptobrevin PF00957.21 KND95619.1 - 9.7e-27 92.6 1.4 1.1e-26 92.5 1.4 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF1100 PF06500.11 KND95619.1 - 0.043 12.6 0.0 0.047 12.5 0.0 1.0 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) UPF0258 PF06789.12 KND95619.1 - 0.079 13.1 0.2 0.079 13.1 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) SNARE PF05739.19 KND95619.1 - 0.89 9.6 13.3 1.5 8.9 8.2 2.3 2 1 0 2 2 2 0 SNARE domain GCV_H PF01597.19 KND95620.1 - 9.1e-41 138.6 0.4 1.1e-40 138.3 0.4 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 KND95620.1 - 0.027 14.4 0.1 0.045 13.7 0.1 1.3 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 KND95620.1 - 0.03 14.1 0.2 0.064 13.1 0.2 1.5 1 0 0 1 1 1 0 Biotin-requiring enzyme IucA_IucC PF04183.12 KND95620.1 - 0.15 11.6 0.1 0.72 9.4 0.1 1.9 1 1 0 2 2 2 0 IucA / IucC family HSP70 PF00012.20 KND95622.1 - 6e-259 860.3 7.9 6.8e-259 860.1 7.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KND95622.1 - 1.4e-14 53.7 0.1 6.7e-13 48.2 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KND95622.1 - 0.0023 17.7 0.0 0.0054 16.5 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain PilM_2 PF11104.8 KND95622.1 - 0.05 12.6 0.0 0.24 10.4 0.0 2.0 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; SWI-SNF_Ssr4 PF08549.10 KND95622.1 - 2.6 6.6 11.2 0.64 8.6 0.2 2.1 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) Cnd1_N PF12922.7 KND95622.1 - 7.3 6.4 7.7 0.41 10.5 2.4 1.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term Na_Ca_ex PF01699.24 KND95623.1 - 2.6e-35 121.6 52.0 1.1e-18 67.7 16.5 3.1 4 0 0 4 4 4 2 Sodium/calcium exchanger protein S_4TM PF18159.1 KND95623.1 - 0.025 13.9 1.7 0.03 13.6 0.0 2.0 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain AAA PF00004.29 KND95625.1 - 8.7e-98 323.9 0.0 5.9e-48 162.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KND95625.1 - 3.3e-24 84.4 2.7 6.8e-13 48.2 1.0 3.0 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 KND95625.1 - 3.4e-17 62.4 0.8 1.2e-16 60.7 0.3 2.3 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 KND95625.1 - 4.6e-14 52.9 0.0 1.7e-07 31.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KND95625.1 - 7e-14 51.9 0.0 5.4e-06 26.2 0.0 3.0 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KND95625.1 - 2e-11 44.2 0.0 8.7e-06 26.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KND95625.1 - 3.5e-11 43.8 0.0 0.001 19.5 0.0 4.5 2 2 0 2 2 2 2 AAA ATPase domain CDC48_2 PF02933.17 KND95625.1 - 3.8e-11 42.6 0.0 9.2e-11 41.4 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 KND95625.1 - 7.5e-11 42.2 0.6 1.9e-05 24.7 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KND95625.1 - 2.6e-09 36.8 0.1 0.0011 18.2 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 KND95625.1 - 2.2e-08 34.5 2.7 0.064 13.5 0.0 4.7 3 2 1 4 4 4 2 AAA domain IstB_IS21 PF01695.17 KND95625.1 - 2.3e-07 30.7 0.1 0.017 14.8 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein Vps4_C PF09336.10 KND95625.1 - 2.6e-07 30.5 0.5 2.6e-05 24.1 0.0 2.9 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_14 PF13173.6 KND95625.1 - 2.8e-07 30.6 0.0 0.008 16.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KND95625.1 - 4.8e-07 30.1 0.0 0.036 14.5 0.0 3.5 4 0 0 4 4 2 2 RNA helicase Mg_chelatase PF01078.21 KND95625.1 - 5.1e-07 29.3 0.5 0.031 13.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KND95625.1 - 3.6e-06 26.5 0.7 0.46 9.8 0.1 3.5 3 0 0 3 3 3 2 KaiC AAA_18 PF13238.6 KND95625.1 - 4.1e-06 27.4 0.0 0.18 12.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 KND95625.1 - 7e-06 26.6 0.1 0.088 13.3 0.0 4.1 3 1 0 3 3 3 1 ABC transporter AAA_7 PF12775.7 KND95625.1 - 1.8e-05 24.3 0.2 0.11 11.9 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 KND95625.1 - 3e-05 23.8 0.2 0.064 13.0 0.0 3.0 3 1 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 KND95625.1 - 4.1e-05 23.3 0.1 0.25 11.0 0.0 3.4 3 1 0 3 3 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 KND95625.1 - 5.9e-05 22.7 5.6 1.1 8.7 0.1 4.2 2 2 2 4 4 4 1 AAA domain Bac_DnaA PF00308.18 KND95625.1 - 6.3e-05 22.9 0.4 0.057 13.3 0.0 3.3 4 1 0 4 4 3 1 Bacterial dnaA protein AAA_28 PF13521.6 KND95625.1 - 7.3e-05 23.1 0.0 0.47 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 KND95625.1 - 0.00011 21.4 0.1 0.42 9.7 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 KND95625.1 - 0.00011 22.6 0.1 0.35 11.3 0.0 3.1 3 0 0 3 3 2 1 AAA domain ResIII PF04851.15 KND95625.1 - 0.00017 21.7 0.0 0.038 14.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KND95625.1 - 0.00017 21.1 2.1 0.11 11.9 0.1 2.7 3 0 0 3 3 2 2 PhoH-like protein DUF815 PF05673.13 KND95625.1 - 0.00028 20.1 0.0 0.26 10.4 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF815) AAA_3 PF07726.11 KND95625.1 - 0.00037 20.4 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KND95625.1 - 0.00042 20.3 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 KND95625.1 - 0.0017 18.2 1.7 1.5 8.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KND95625.1 - 0.0021 17.8 0.4 2.6 7.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KND95625.1 - 0.0025 18.2 1.2 3.1 8.1 0.0 3.7 3 1 0 4 4 3 1 AAA domain DUF2075 PF09848.9 KND95625.1 - 0.0029 16.9 0.0 2.5 7.3 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 KND95625.1 - 0.0031 16.8 0.2 1.6 7.9 0.0 3.3 4 0 0 4 4 2 1 Zeta toxin NACHT PF05729.12 KND95625.1 - 0.0034 17.3 0.2 5.8 6.8 0.0 3.2 3 0 0 3 3 3 0 NACHT domain ATPase_2 PF01637.18 KND95625.1 - 0.0071 16.3 1.4 1.6 8.6 0.1 4.0 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea IPT PF01745.16 KND95625.1 - 0.017 14.6 0.2 2.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase T2SSE PF00437.20 KND95625.1 - 0.023 13.8 0.0 3.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.22 KND95625.1 - 0.033 13.4 0.2 7.7 5.6 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain Cytidylate_kin PF02224.18 KND95625.1 - 0.037 13.7 0.0 9.8 5.8 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase Sigma54_activ_2 PF14532.6 KND95625.1 - 0.039 14.1 0.0 5.3 7.2 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 KND95625.1 - 0.046 13.6 2.0 8.3 6.3 0.0 4.0 4 0 0 4 4 4 0 NTPase KAP_NTPase PF07693.14 KND95625.1 - 0.076 12.2 0.0 2.6 7.2 0.0 2.6 2 1 1 3 3 3 0 KAP family P-loop domain Viral_helicase1 PF01443.18 KND95625.1 - 0.088 12.5 0.0 17 5.1 0.0 2.9 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Molydop_binding PF01568.21 KND95625.1 - 0.12 12.4 0.1 0.4 10.7 0.1 1.8 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain AAA_6 PF12774.7 KND95625.1 - 0.28 10.1 0.5 9.4 5.1 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region ABC2_membrane PF01061.24 KND95627.1 - 4.6e-81 271.2 45.5 3e-42 144.4 25.1 3.1 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KND95627.1 - 9.5e-41 139.5 0.0 6.4e-19 68.8 0.0 2.9 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KND95627.1 - 2.3e-32 110.7 7.0 1.5e-30 104.9 0.0 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KND95627.1 - 1.7e-18 67.0 0.3 5e-18 65.5 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 KND95627.1 - 1.1e-07 31.9 0.1 6.8e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KND95627.1 - 1.1e-06 28.4 0.2 0.00031 20.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KND95627.1 - 3.1e-05 24.3 0.2 0.037 14.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.6 KND95627.1 - 3.3e-05 23.5 0.7 0.0042 16.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KND95627.1 - 6.3e-05 23.4 0.1 0.0064 16.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 KND95627.1 - 7.1e-05 22.1 35.4 0.0011 18.1 3.9 2.7 3 1 0 3 3 2 2 ABC-2 family transporter protein AAA_33 PF13671.6 KND95627.1 - 0.00014 22.0 1.7 0.61 10.2 0.0 3.1 4 0 0 4 4 2 2 AAA domain AAA_18 PF13238.6 KND95627.1 - 0.00019 22.0 0.0 0.015 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KND95627.1 - 0.00021 20.8 0.0 0.089 12.2 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 KND95627.1 - 0.00042 20.6 0.1 0.012 15.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KND95627.1 - 0.00063 19.8 0.1 0.093 12.8 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 KND95627.1 - 0.00088 19.0 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KND95627.1 - 0.0016 19.0 0.2 0.047 14.2 0.0 2.7 3 0 0 3 3 2 1 AAA domain ABC_ATPase PF09818.9 KND95627.1 - 0.0029 16.5 0.1 0.037 12.8 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class NACHT PF05729.12 KND95627.1 - 0.0043 17.0 0.6 0.26 11.2 0.0 2.8 3 0 0 3 3 3 1 NACHT domain AAA_21 PF13304.6 KND95627.1 - 0.0059 16.5 2.5 0.74 9.6 0.2 3.2 3 1 1 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 KND95627.1 - 0.01 15.4 1.1 0.43 10.1 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain dNK PF01712.19 KND95627.1 - 0.013 15.4 0.0 5.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase IstB_IS21 PF01695.17 KND95627.1 - 0.1 12.3 0.0 1 9.1 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Ploopntkinase3 PF18751.1 KND95627.1 - 0.17 11.8 0.1 26 4.7 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 KND95627.1 - 0.18 11.1 0.1 1.6 8.0 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin YCII PF03795.14 KND95628.1 - 3.4e-06 27.4 0.0 4.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain AAA_2 PF07724.14 KND95630.1 - 4.6e-46 157.0 2.1 1.8e-44 151.8 0.0 3.3 4 0 0 4 4 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KND95630.1 - 3.4e-31 107.3 5.8 8.2e-31 106.0 0.8 3.0 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 KND95630.1 - 9e-23 81.1 0.2 2.9e-12 47.2 0.1 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KND95630.1 - 5.8e-22 77.5 0.5 2.1e-21 75.8 0.5 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KND95630.1 - 6.5e-14 52.1 0.0 2.7e-08 33.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KND95630.1 - 2.5e-12 46.8 0.6 8.6e-07 28.8 0.0 3.3 2 1 0 2 2 2 2 Sigma-54 interaction domain Clp_N PF02861.20 KND95630.1 - 2.5e-11 43.5 1.4 1.3e-08 34.8 0.2 3.5 3 0 0 3 3 3 1 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 KND95630.1 - 2.7e-10 40.9 7.5 7.1e-06 26.5 0.3 4.4 3 2 1 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 KND95630.1 - 5.8e-07 29.9 2.0 0.099 12.9 0.3 4.6 3 2 0 3 3 2 2 AAA domain AAA_14 PF13173.6 KND95630.1 - 9e-07 29.0 0.0 0.071 13.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain ATPase_2 PF01637.18 KND95630.1 - 9.7e-06 25.7 3.8 0.084 12.8 0.2 4.3 3 1 1 4 4 3 2 ATPase domain predominantly from Archaea TniB PF05621.11 KND95630.1 - 4.3e-05 23.0 0.0 0.021 14.2 0.0 3.5 2 1 0 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 KND95630.1 - 0.00013 21.5 0.0 0.046 13.2 0.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_30 PF13604.6 KND95630.1 - 0.00017 21.4 0.1 0.0061 16.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KND95630.1 - 0.00042 20.3 0.0 0.09 12.7 0.0 2.8 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 KND95630.1 - 0.00043 19.7 0.0 2.4 7.5 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 KND95630.1 - 0.0011 18.9 0.3 0.14 12.1 0.0 3.0 3 0 0 3 3 2 1 RsgA GTPase TsaE PF02367.17 KND95630.1 - 0.0019 18.2 0.0 0.097 12.7 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KND95630.1 - 0.0022 18.2 0.0 0.24 11.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 KND95630.1 - 0.0024 18.1 0.0 0.58 10.4 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_3 PF07726.11 KND95630.1 - 0.0072 16.2 0.0 0.25 11.2 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KND95630.1 - 0.013 14.7 0.2 2.6 7.2 0.0 3.1 3 0 0 3 3 3 0 NB-ARC domain IstB_IS21 PF01695.17 KND95630.1 - 0.014 15.2 0.1 0.88 9.3 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 KND95630.1 - 0.015 15.0 0.0 6.3 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_8 PF12780.7 KND95630.1 - 0.015 14.6 0.6 0.48 9.7 0.4 2.8 2 1 0 2 2 2 0 P-loop containing dynein motor region D4 ABC_tran PF00005.27 KND95630.1 - 0.023 15.2 0.1 12 6.4 0.0 3.1 2 0 0 2 2 2 0 ABC transporter Torsin PF06309.11 KND95630.1 - 0.024 14.7 0.0 0.21 11.7 0.0 2.5 3 0 0 3 3 2 0 Torsin AAA_19 PF13245.6 KND95630.1 - 0.025 14.9 0.5 1.2 9.5 0.3 3.5 3 1 0 3 3 2 0 AAA domain SRP54 PF00448.22 KND95630.1 - 0.026 14.1 0.0 1 9.0 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain APS_kinase PF01583.20 KND95630.1 - 0.036 13.9 0.1 0.36 10.7 0.0 2.6 3 0 0 3 3 3 0 Adenylylsulphate kinase PEPCK_ATP PF01293.20 KND95630.1 - 0.064 11.9 0.0 0.35 9.5 0.0 1.9 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase DUF815 PF05673.13 KND95630.1 - 0.068 12.3 1.9 1.2 8.2 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 KND95630.1 - 0.069 12.9 0.1 4.5 7.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KND95630.1 - 0.092 12.0 2.3 0.74 9.1 0.0 3.2 4 0 0 4 4 4 0 Zeta toxin FlaC_arch PF05377.11 KND95630.1 - 0.13 12.7 1.9 0.82 10.1 1.9 2.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) PduV-EutP PF10662.9 KND95630.1 - 0.15 11.8 1.3 11 5.7 0.0 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Nup54 PF13874.6 KND95630.1 - 0.23 11.6 4.4 0.99 9.5 4.4 2.1 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 AAA_18 PF13238.6 KND95630.1 - 0.4 11.2 3.3 13 6.3 0.0 3.6 4 0 0 4 4 2 0 AAA domain V_ATPase_I PF01496.19 KND95630.1 - 2.3 6.0 4.9 3.6 5.4 4.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-H PF05837.12 KND95630.1 - 6 7.3 12.6 2.4 8.6 0.7 3.1 1 1 1 2 2 1 0 Centromere protein H (CENP-H) eIF-6 PF01912.18 KND95631.1 - 1.4e-82 275.8 0.5 1.8e-82 275.5 0.5 1.1 1 0 0 1 1 1 1 eIF-6 family TRP PF06011.12 KND95633.1 - 4.8e-155 516.5 32.9 4.8e-155 516.5 32.9 1.4 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KND95633.1 - 3.2e-38 131.2 2.3 6.7e-38 130.2 2.3 1.6 1 0 0 1 1 1 1 ML-like domain MARVEL PF01284.23 KND95636.1 - 3.8e-08 33.5 15.2 5.3e-08 33.0 15.2 1.2 1 0 0 1 1 1 1 Membrane-associating domain 7tm_2 PF00002.24 KND95636.1 - 0.14 11.4 9.5 0.22 10.8 9.5 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) TMEM192 PF14802.6 KND95636.1 - 5 6.1 7.2 23 4.0 0.1 2.3 2 0 0 2 2 2 0 TMEM192 family 2-oxoacid_dh PF00198.23 KND95637.1 - 1.6e-79 266.6 0.1 2.3e-79 266.1 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KND95637.1 - 7e-19 67.4 3.2 1.2e-18 66.6 3.2 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.19 KND95637.1 - 2.5e-05 24.1 0.9 6.9e-05 22.7 0.6 1.8 2 0 0 2 2 2 1 Glycine cleavage H-protein HlyD_3 PF13437.6 KND95637.1 - 8e-05 23.3 1.1 0.013 16.2 0.2 2.5 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 KND95637.1 - 0.00016 21.4 0.5 0.01 15.6 0.2 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like RnfC_N PF13375.6 KND95637.1 - 0.0083 16.1 0.3 0.063 13.2 0.3 2.3 1 1 0 1 1 1 1 RnfC Barrel sandwich hybrid domain RNA_pol_Rpc4 PF05132.14 KND95637.1 - 0.17 12.3 7.2 0.28 11.6 7.2 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 KND95637.1 - 0.19 11.5 13.8 0.29 10.9 13.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KND95637.1 - 0.59 8.8 5.0 0.84 8.3 5.0 1.2 1 0 0 1 1 1 0 Presenilin GAGA_bind PF06217.12 KND95637.1 - 0.8 9.9 5.8 1.1 9.5 5.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family CPSF100_C PF13299.6 KND95637.1 - 1 9.5 7.4 1.9 8.6 6.5 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal NPR3 PF03666.13 KND95637.1 - 7.1 5.3 9.0 10 4.7 9.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 zf-C2H2 PF00096.26 KND95638.1 - 2.7e-12 46.4 23.7 1.9e-05 24.8 3.8 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND95638.1 - 4.5e-08 33.3 20.4 0.00026 21.5 2.8 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KND95638.1 - 3.3e-06 27.3 18.9 5.8e-06 26.5 0.5 3.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KND95638.1 - 0.0009 19.5 4.5 0.0059 16.9 0.3 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KND95638.1 - 0.013 15.5 1.7 0.013 15.5 1.7 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KND95638.1 - 0.093 12.9 2.6 2 8.6 0.0 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger C5HCH PF17982.1 KND95638.1 - 0.15 12.2 4.8 0.33 11.1 4.8 1.5 1 0 0 1 1 1 0 NSD Cys-His rich domain zf-TRAF PF02176.18 KND95638.1 - 2.7 8.8 9.5 0.076 13.7 1.7 2.2 1 1 2 3 3 3 0 TRAF-type zinc finger zf-C2H2 PF00096.26 KND95639.1 - 1.4e-08 34.7 17.3 0.00023 21.4 1.2 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KND95639.1 - 5.8e-08 32.8 20.7 8.1e-08 32.4 5.5 3.9 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KND95639.1 - 8.3e-06 25.7 8.9 0.00066 19.6 1.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KND95639.1 - 4.6e-05 23.9 18.1 0.011 16.5 1.2 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-MYST PF17772.1 KND95639.1 - 0.0034 17.0 4.0 0.024 14.3 0.7 2.5 1 1 1 2 2 2 1 MYST family zinc finger domain zf-Di19 PF05605.12 KND95639.1 - 0.0046 17.2 3.9 0.016 15.5 3.9 2.0 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KND95639.1 - 0.019 15.3 7.7 2.7 8.5 0.4 3.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KND95639.1 - 0.13 12.5 7.1 0.29 11.5 1.1 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 KND95639.1 - 0.47 10.5 7.9 0.5 10.4 2.6 2.5 1 1 1 2 2 2 0 BED zinc finger zf-C2HC_2 PF13913.6 KND95639.1 - 1.9 8.5 7.4 6.1 6.9 0.2 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Kelch_4 PF13418.6 KND95640.1 - 2.9e-06 27.2 0.8 0.42 10.7 0.0 4.1 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KND95640.1 - 0.00029 21.0 6.4 0.00074 19.7 0.1 4.0 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.25 KND95640.1 - 0.0079 15.8 1.5 2.1 8.0 0.1 3.1 3 0 0 3 3 3 2 Kelch motif DUF5074 PF16819.5 KND95640.1 - 0.12 12.4 0.9 0.6 10.2 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5074) ETRAMP PF09716.10 KND95640.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Kelch_3 PF13415.6 KND95640.1 - 0.98 9.8 5.0 2.6 8.5 0.1 3.6 4 0 0 4 4 4 0 Galactose oxidase, central domain Chorismate_synt PF01264.21 KND95641.1 - 3.3e-140 466.4 0.0 3.8e-140 466.2 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase SRPRB PF09439.10 KND95642.1 - 1.4e-31 109.4 0.1 1.8e-31 109.0 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KND95642.1 - 1.3e-07 31.2 0.0 2.5e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KND95642.1 - 8.1e-07 29.1 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KND95642.1 - 2.2e-06 27.3 0.0 1.1e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KND95642.1 - 0.00012 22.0 1.1 0.0061 16.4 0.2 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 KND95642.1 - 0.0016 17.8 0.5 0.0032 16.9 0.5 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KND95642.1 - 0.0071 15.9 0.1 0.017 14.7 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_21 PF13304.6 KND95642.1 - 0.0071 16.2 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KND95642.1 - 0.016 15.8 1.5 0.025 15.1 1.5 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KND95642.1 - 0.037 13.9 0.4 0.53 10.2 0.4 2.4 1 1 0 1 1 1 0 NACHT domain SRP54 PF00448.22 KND95642.1 - 0.042 13.5 0.1 0.87 9.2 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Roc PF08477.13 KND95642.1 - 0.063 13.5 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KND95642.1 - 0.084 12.8 0.1 0.91 9.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase DLIC PF05783.11 KND95642.1 - 0.1 11.4 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Vfa1 PF08432.10 KND95643.1 - 3.3e-44 151.4 9.2 3.7e-44 151.2 9.2 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 FapA PF03961.13 KND95643.1 - 0.58 8.7 3.3 0.76 8.3 3.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A MBD PF01429.19 KND95646.1 - 0.034 13.9 0.7 0.042 13.6 0.7 1.1 1 0 0 1 1 1 0 Methyl-CpG binding domain Metallophos PF00149.28 KND95647.1 - 1.2e-40 140.2 0.1 1.6e-40 139.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KND95647.1 - 4e-22 78.4 1.1 6.6e-22 77.7 0.6 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Aminotran_1_2 PF00155.21 KND95649.1 - 8.5e-78 262.0 0.0 9.7e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Esterase PF00756.20 KND95649.1 - 0.089 12.4 0.0 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 Putative esterase EMP24_GP25L PF01105.24 KND95651.1 - 6.3e-47 159.9 0.3 7.5e-47 159.6 0.3 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pox_EPC_I2-L1 PF12575.8 KND95651.1 - 0.22 11.8 0.1 0.22 11.8 0.1 1.8 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 Pkinase PF00069.25 KND95653.1 - 3.8e-42 144.5 0.0 4.5e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND95653.1 - 1.6e-16 60.4 0.0 2e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KND95653.1 - 0.043 12.8 0.0 0.069 12.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain NepR PF18557.1 KND95653.1 - 1.9 8.2 5.8 1.3 8.7 0.3 2.5 2 0 0 2 2 2 0 Anti-sigma factor NepR DUF2406 PF10295.9 KND95654.1 - 3.1e-24 85.4 0.1 9.6e-24 83.9 0.1 1.9 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) TPR_1 PF00515.28 KND95657.1 - 7.9e-07 28.6 0.3 0.04 13.7 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KND95657.1 - 1e-05 25.3 0.0 0.48 10.7 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KND95657.1 - 4.5e-05 23.7 0.0 0.0018 18.6 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KND95657.1 - 0.0052 17.3 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KND95657.1 - 0.011 15.8 0.1 2 8.8 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KND95657.1 - 0.026 14.6 0.2 0.5 10.5 0.0 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 KND95657.1 - 0.16 12.1 1.4 0.91 9.6 0.0 2.9 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Trypan_PARP PF05887.11 KND95657.1 - 3.1 7.8 21.5 0.96 9.4 5.1 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Nop10p PF04135.12 KND95658.1 - 3.6e-22 78.2 0.2 4e-22 78.0 0.2 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family DASH_Dad4 PF08650.10 KND95659.1 - 1.4e-28 98.6 4.5 1.6e-28 98.4 4.5 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.10 KND95659.1 - 0.0064 16.7 1.6 0.0087 16.2 1.6 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad2 PF08654.10 KND95659.1 - 0.02 15.3 0.6 0.023 15.1 0.6 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad2 Zn_clus PF00172.18 KND95660.1 - 2.6e-08 33.8 8.8 4.4e-08 33.1 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC45 PF02724.14 KND95660.1 - 1.4 7.1 7.4 2.1 6.5 7.4 1.2 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.16 KND95661.1 - 3.2e-26 92.1 29.1 4.6e-19 68.5 4.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KND95661.1 - 6.6e-07 28.2 20.0 1.5e-06 27.0 9.1 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 KND95661.1 - 9.5e-07 28.0 9.7 9.5e-07 28.0 9.7 2.5 2 1 0 2 2 2 1 MFS_1 like family TRI12 PF06609.13 KND95661.1 - 0.0073 14.8 0.5 0.0073 14.8 0.5 1.8 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) FA_desaturase PF00487.24 KND95661.1 - 2.4 7.9 8.5 6.7 6.5 0.7 2.4 2 0 0 2 2 2 0 Fatty acid desaturase ATG22 PF11700.8 KND95661.1 - 4.2 5.9 16.9 0.053 12.1 7.9 2.2 2 2 0 2 2 2 0 Vacuole effluxer Atg22 like AA_permease PF00324.21 KND95663.1 - 1.9e-116 389.5 46.3 2.4e-116 389.2 46.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND95663.1 - 1.5e-41 142.7 51.2 1.8e-41 142.4 51.2 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3767 PF12597.8 KND95663.1 - 0.044 13.6 0.4 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3767) PQ-loop PF04193.14 KND95665.1 - 0.11 12.3 0.6 0.16 11.7 0.6 1.3 1 0 0 1 1 1 0 PQ loop repeat zf-C2H2 PF00096.26 KND95667.1 - 1.6e-12 47.1 19.5 3.4e-06 27.2 3.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND95667.1 - 7.7e-07 29.4 15.7 0.0073 17.1 2.2 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KND95667.1 - 1.2e-05 25.5 22.6 3.2e-05 24.2 1.9 4.9 5 1 0 5 5 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KND95667.1 - 2.2e-05 24.3 9.3 7.2e-05 22.7 2.2 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KND95667.1 - 0.0053 17.0 16.4 0.0057 16.9 1.0 3.8 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KND95667.1 - 0.013 15.3 1.2 2.4 8.1 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-met PF12874.7 KND95667.1 - 0.19 12.2 4.1 2 8.9 0.5 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type CpXC PF14353.6 KND95667.1 - 0.26 11.4 5.2 0.15 12.1 0.5 2.5 2 0 0 2 2 2 0 CpXC protein Med15 PF09606.10 KND95667.1 - 1.3 7.6 44.5 2.2 6.9 44.5 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.14 KND95667.1 - 2.3 8.1 17.9 4.4 7.2 17.9 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) C5HCH PF17982.1 KND95667.1 - 2.6 8.3 5.0 2.3 8.4 1.1 2.3 2 0 0 2 2 2 0 NSD Cys-His rich domain Rpr2 PF04032.16 KND95667.1 - 4.9 7.5 8.5 0.15 12.4 0.9 2.4 3 0 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Carn_acyltransf PF00755.20 KND95672.1 - 2.5e-142 475.5 0.1 3e-142 475.3 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CRAL_TRIO PF00650.20 KND95674.1 - 6.7e-37 126.7 0.1 9.9e-37 126.1 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KND95674.1 - 1.2e-09 38.2 0.0 2.6e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KND95674.1 - 0.0013 18.9 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RasGAP PF00616.19 KND95675.1 - 9.2e-56 188.8 3.1 1.8e-55 187.9 3.1 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KND95675.1 - 3.3e-05 24.1 0.2 0.00014 22.1 0.2 2.0 1 0 0 1 1 1 1 C2 domain DUF327 PF03885.13 KND95675.1 - 0.073 13.0 0.1 0.073 13.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF327) FAM176 PF14851.6 KND95675.1 - 0.15 11.7 2.4 0.3 10.7 2.4 1.4 1 0 0 1 1 1 0 FAM176 family UPF1_Zn_bind PF09416.10 KND95678.1 - 2.1e-60 203.1 10.1 1.4e-59 200.5 6.3 2.5 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KND95678.1 - 3.5e-56 190.0 0.0 6.2e-56 189.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KND95678.1 - 1.7e-48 165.7 0.9 1.3e-25 90.7 0.1 2.2 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KND95678.1 - 2.6e-20 72.5 0.0 4.8e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KND95678.1 - 2.5e-14 53.4 0.1 1e-13 51.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KND95678.1 - 1.3e-11 45.1 0.1 4.4e-11 43.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KND95678.1 - 7.9e-05 22.7 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KND95678.1 - 0.00013 21.4 0.0 0.024 13.9 0.0 3.2 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 KND95678.1 - 0.00015 21.6 0.1 1.7 8.3 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KND95678.1 - 0.0028 17.2 0.1 0.094 12.2 0.0 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 KND95678.1 - 0.0033 17.3 0.0 0.0067 16.3 0.0 1.5 1 0 0 1 1 1 1 Helicase PIF1 PF05970.14 KND95678.1 - 0.0042 16.3 0.1 0.44 9.7 0.0 2.4 2 0 0 2 2 2 1 PIF1-like helicase PhoH PF02562.16 KND95678.1 - 0.012 15.0 0.0 0.033 13.6 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein DEAD PF00270.29 KND95678.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 KND95678.1 - 0.027 14.5 0.4 0.052 13.5 0.4 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_22 PF13401.6 KND95678.1 - 0.066 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KND95678.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PHD PF00628.29 KND95678.1 - 2.5 8.0 7.5 0.87 9.5 3.7 2.1 2 0 0 2 2 2 0 PHD-finger zf-AN1 PF01428.16 KND95678.1 - 2.7 8.2 5.7 7.2 6.9 5.7 1.7 1 0 0 1 1 1 0 AN1-like Zinc finger PulG PF11773.8 KND95680.1 - 0.2 11.5 0.0 0.34 10.8 0.0 1.4 1 1 0 1 1 1 0 Type II secretory pathway pseudopilin DUF2052 PF09747.9 KND95683.1 - 0.29 11.2 12.1 0.43 10.7 12.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF4366 PF14283.6 KND95683.1 - 0.35 10.9 6.8 0.53 10.3 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) RRN3 PF05327.11 KND95683.1 - 1.2 7.6 4.9 1.4 7.4 4.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 zn-ribbon_14 PF16503.5 KND95695.1 - 0.043 13.3 0.9 0.08 12.5 0.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon eIF-1a PF01176.19 KND95695.1 - 0.054 13.3 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 DUF2892 PF11127.8 KND95698.1 - 4.4 7.4 7.0 0.61 10.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) DUF3488 PF11992.8 KND95699.1 - 0.82 8.6 8.1 1 8.2 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) UQ_con PF00179.26 KND95701.1 - 2.5e-45 153.6 0.0 2.9e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KND95701.1 - 0.00086 19.0 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KND95701.1 - 0.054 13.4 0.0 0.12 12.2 0.0 1.6 1 1 0 1 1 1 0 UEV domain CRCB PF02537.15 KND95704.1 - 4e-31 107.2 29.1 5e-20 71.6 9.3 2.8 2 1 1 3 3 3 2 CrcB-like protein, Camphor Resistance (CrcB) PhoLip_ATPase_C PF16212.5 KND95706.1 - 3.3e-70 236.7 30.7 3.3e-70 236.7 30.7 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KND95706.1 - 8.1e-13 47.9 1.0 1.6e-12 46.9 0.2 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KND95706.1 - 3e-12 46.5 0.0 1.6e-11 44.1 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KND95706.1 - 2e-10 41.3 2.1 8.8e-06 26.2 0.7 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KND95706.1 - 1.6e-05 24.5 0.0 6e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KND95706.1 - 0.0017 18.1 0.2 0.0057 16.4 0.2 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2871 PF11070.8 KND95706.1 - 1.2 9.4 5.6 1.2 9.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2871) Mito_carr PF00153.27 KND95710.1 - 5.3e-67 221.8 6.5 2.4e-23 81.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SAM_decarbox PF01536.16 KND95712.1 - 2.7e-122 408.2 0.0 3.2e-122 408.0 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Pkinase PF00069.25 KND95717.1 - 9.1e-62 208.8 0.0 1.6e-61 208.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND95717.1 - 2.5e-31 108.9 0.0 3.9e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND95717.1 - 1.9e-05 24.2 0.0 4.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 KND95717.1 - 0.00014 22.5 0.7 0.00039 21.1 0.7 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 KND95717.1 - 0.0015 17.4 0.0 0.0025 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Dynamin_M PF01031.20 KND95718.1 - 1e-98 330.1 0.3 1e-98 330.1 0.3 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KND95718.1 - 1.6e-56 190.9 0.0 3.6e-56 189.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KND95718.1 - 4.4e-29 100.5 3.2 1.4e-28 98.9 3.2 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KND95718.1 - 2.9e-05 24.1 0.3 0.00021 21.3 0.2 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KND95718.1 - 0.14 11.7 0.3 14 5.2 0.1 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B DUF2076 PF09849.9 KND95718.1 - 0.18 11.8 2.0 0.31 11.0 2.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Macro PF01661.21 KND95719.1 - 3.8e-26 91.4 0.0 4.6e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Macro domain EGF_3 PF12947.7 KND95721.1 - 0.034 14.3 1.3 0.061 13.5 1.3 1.5 1 0 0 1 1 1 0 EGF domain TruB_N PF01509.18 KND95723.1 - 6.6e-40 136.9 0.1 2e-39 135.3 0.1 1.9 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KND95723.1 - 4.6e-06 26.7 0.1 0.00018 21.6 0.0 3.0 3 0 0 3 3 3 1 tRNA pseudouridylate synthase B C-terminal domain Erf4 PF10256.9 KND95724.1 - 1.7e-25 89.4 0.0 2.4e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family RE_EcoO109I PF14511.6 KND95724.1 - 0.096 12.3 0.0 0.22 11.1 0.0 1.5 1 1 0 1 1 1 0 Type II restriction endonuclease EcoO109I PPR_2 PF13041.6 KND95726.1 - 7.3e-16 58.1 7.9 6.2e-06 26.3 0.3 5.1 4 1 2 6 6 6 4 PPR repeat family PPR PF01535.20 KND95726.1 - 1.5e-07 31.2 11.1 0.013 15.7 0.3 6.6 8 0 0 8 8 8 2 PPR repeat PPR_3 PF13812.6 KND95726.1 - 6e-05 23.1 0.5 1.1 9.4 0.0 4.4 4 0 0 4 4 4 1 Pentatricopeptide repeat domain AEP1 PF17049.5 KND95726.1 - 0.04 13.0 0.9 0.076 12.1 0.9 1.5 1 0 0 1 1 1 0 ATPase expression protein 1 Mad3_BUB1_I_2 PF17014.5 KND95726.1 - 0.084 13.0 3.3 2.2 8.4 0.1 2.9 3 0 0 3 3 3 0 Putative Mad3/BUB1 like region 1 protein Cyto_heme_lyase PF01265.17 KND95728.1 - 4.3e-94 315.4 7.9 7.8e-93 311.2 7.9 2.3 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase OTU PF02338.19 KND95732.1 - 1.3e-21 77.4 0.1 3.4e-21 76.0 0.0 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KND95732.1 - 4.9e-06 26.2 0.2 4.9e-06 26.2 0.2 2.4 2 1 0 2 2 2 1 Peptidase C65 Otubain T2SSM PF04612.12 KND95732.1 - 0.044 13.8 1.1 0.15 12.1 1.1 1.9 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M CbiG_C PF01890.16 KND95732.1 - 0.21 12.2 1.3 1.8 9.2 0.3 2.7 3 0 0 3 3 3 0 Cobalamin synthesis G C-terminus Cep57_MT_bd PF06657.13 KND95732.1 - 6.6 7.3 12.4 0.83 10.2 5.4 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Cyclin_N PF00134.23 KND95734.1 - 1.9e-36 124.6 1.3 2.4e-36 124.3 0.4 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cupin_8 PF13621.6 KND95735.1 - 1.3e-41 143.0 0.0 1.1e-39 136.7 0.0 2.4 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KND95735.1 - 3.1e-08 33.5 0.0 4e-06 26.5 0.0 2.5 2 0 0 2 2 2 2 Cupin superfamily protein PI3K_1B_p101 PF10486.9 KND95735.1 - 0.58 7.9 2.6 0.72 7.6 2.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit ETF_QO PF05187.13 KND95738.1 - 3.5e-45 152.4 0.7 6e-45 151.6 0.7 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 KND95738.1 - 2.9e-08 33.2 0.2 0.00068 18.8 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KND95738.1 - 5.7e-08 32.7 0.1 8.3e-05 22.3 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KND95738.1 - 7.5e-06 26.1 0.0 4.9e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KND95738.1 - 7.6e-06 25.3 0.0 0.0046 16.2 0.0 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 KND95738.1 - 0.00046 19.5 0.0 0.00091 18.5 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KND95738.1 - 0.00051 18.8 0.2 0.0038 16.0 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KND95738.1 - 0.0018 17.6 0.1 0.003 16.9 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KND95738.1 - 0.0018 17.6 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Fer4_7 PF12838.7 KND95738.1 - 0.022 15.3 0.6 0.061 13.9 0.6 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain K_oxygenase PF13434.6 KND95738.1 - 0.029 13.5 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KND95738.1 - 0.061 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KND95738.1 - 0.071 12.2 0.2 0.1 11.6 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 KND95738.1 - 0.22 10.8 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_6 PF08030.12 KND95739.1 - 2.4e-21 76.5 0.0 4.7e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KND95739.1 - 5.2e-21 75.0 14.0 5.2e-21 75.0 14.0 2.3 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KND95739.1 - 3.2e-20 72.2 0.0 6.1e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain ACT_7 PF13840.6 KND95739.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 ACT domain NAD_binding_1 PF00175.21 KND95739.1 - 0.19 12.4 0.0 0.76 10.5 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain CitMHS PF03600.16 KND95739.1 - 4.6 6.3 7.8 8.1 5.5 7.8 1.4 1 0 0 1 1 1 0 Citrate transporter RhoGEF PF00621.20 KND95741.1 - 5.2e-31 108.3 0.8 5.2e-31 108.3 0.8 2.2 3 0 0 3 3 3 1 RhoGEF domain PH_10 PF15411.6 KND95741.1 - 6.7e-24 84.5 0.4 1.4e-23 83.5 0.4 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 KND95741.1 - 1.9e-16 60.1 0.1 5e-16 58.7 0.0 1.8 2 0 0 2 2 2 1 CDC24 Calponin PB1 PF00564.24 KND95741.1 - 1e-07 31.8 2.0 4.8e-07 29.6 0.3 2.6 3 0 0 3 3 3 1 PB1 domain PH PF00169.29 KND95741.1 - 0.12 12.9 0.1 0.43 11.1 0.1 1.9 1 1 0 1 1 1 0 PH domain SpoIISA_toxin PF14171.6 KND95743.1 - 0.021 14.6 0.2 0.021 14.5 0.2 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DUF1398 PF07166.11 KND95744.1 - 0.064 13.3 1.4 0.079 13.0 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) SecE PF00584.20 KND95745.1 - 0.0015 18.4 0.2 0.0015 18.4 0.2 2.8 2 0 0 2 2 2 1 SecE/Sec61-gamma subunits of protein translocation complex DUF3176 PF11374.8 KND95745.1 - 0.083 13.1 0.2 0.56 10.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) Cortexin PF11057.8 KND95745.1 - 0.14 12.0 4.4 0.23 11.3 1.0 2.7 2 0 0 2 2 2 0 Cortexin of kidney PHO4 PF01384.20 KND95745.1 - 1.5 7.8 4.5 0.9 8.5 1.4 2.2 1 1 0 2 2 2 0 Phosphate transporter family Zn_clus PF00172.18 KND95746.1 - 3.5e-08 33.4 14.5 7e-08 32.5 14.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YabA PF06156.13 KND95746.1 - 3.8 8.2 15.2 0.15 12.7 1.7 3.4 3 0 0 3 3 3 0 Initiation control protein YabA TSC22 PF01166.18 KND95746.1 - 5.5 7.4 7.3 7.9 6.9 1.8 3.2 3 0 0 3 3 3 0 TSC-22/dip/bun family Rad9 PF04139.13 KND95748.1 - 1.7e-14 53.9 0.1 2.9e-14 53.2 0.1 1.4 1 1 0 1 1 1 1 Rad9 Rad1 PF02144.16 KND95748.1 - 0.056 12.5 0.1 0.63 9.0 0.1 2.4 2 1 1 3 3 3 0 Repair protein Rad1/Rec1/Rad17 Asp_Glu_race PF01177.22 KND95749.1 - 5.3e-10 39.5 0.0 9.8e-10 38.6 0.0 1.4 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase TLD PF07534.16 KND95750.1 - 7.8e-26 91.0 0.5 1.1e-22 80.7 0.0 2.1 2 0 0 2 2 2 2 TLD MTHFR PF02219.17 KND95751.1 - 2.4e-117 391.3 0.0 4.3e-117 390.5 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Glyco_transf_24 PF18404.1 KND95752.1 - 2.3e-132 440.4 7.0 2.3e-132 440.4 7.0 1.8 2 0 0 2 2 2 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KND95752.1 - 4.9e-32 111.9 0.2 1.3e-31 110.5 0.2 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KND95752.1 - 1.4e-29 103.3 0.1 3.8e-29 101.9 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KND95752.1 - 1.4e-18 67.0 0.0 3.1e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 KND95752.1 - 3.6e-13 49.6 1.2 1.2e-12 47.9 0.2 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KND95752.1 - 1.6e-07 31.1 1.6 4.7e-07 29.6 1.6 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 8 Protamine_like PF06382.11 KND95753.1 - 0.00075 19.7 1.6 0.00092 19.4 1.2 1.4 1 1 0 1 1 1 1 Protamine and protamine like HMG_box_2 PF09011.10 KND95753.1 - 2.3 8.9 6.7 0.18 12.4 0.8 2.3 2 1 0 2 2 2 0 HMG-box domain AAR2 PF05282.11 KND95754.1 - 1e-49 169.8 1.5 1.7e-49 169.1 1.5 1.3 1 0 0 1 1 1 1 AAR2 protein Voltage_CLC PF00654.20 KND95755.1 - 2.6e-73 247.3 17.8 3.6e-73 246.8 17.8 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 KND95755.1 - 0.00026 21.4 0.8 0.039 14.4 0.2 3.2 3 0 0 3 3 3 1 CBS domain WD40 PF00400.32 KND95756.1 - 5.7e-20 71.3 2.1 0.0097 16.7 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND95756.1 - 3.5e-10 40.1 0.0 0.00038 20.7 0.0 5.0 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KND95756.1 - 9.7e-05 21.5 0.6 0.3 10.0 0.0 3.1 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KND95756.1 - 0.0013 18.7 0.0 0.011 15.6 0.0 2.3 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KND95756.1 - 0.0031 16.2 0.1 0.068 11.8 0.1 2.5 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Frtz PF11768.8 KND95756.1 - 0.029 12.7 0.0 1.8 6.8 0.0 2.2 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz zf-RING_14 PF17978.1 KND95756.1 - 0.19 12.2 1.1 0.7 10.4 0.5 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain LisH PF08513.11 KND95758.1 - 0.00019 21.3 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 LisH ALG3 PF05208.13 KND95759.1 - 3.7e-120 401.6 23.5 4.4e-120 401.4 23.5 1.0 1 0 0 1 1 1 1 ALG3 protein TORC_N PF12884.7 KND95760.1 - 0.46 11.3 4.2 2 9.3 4.2 2.1 1 0 0 1 1 1 0 Transducer of regulated CREB activity, N terminus Clc-like PF07062.12 KND95761.1 - 0.05 13.1 0.0 0.051 13.0 0.0 1.1 1 0 0 1 1 1 0 Clc-like Asp PF00026.23 KND95762.1 - 2.7e-63 214.3 3.3 2.5e-53 181.5 0.1 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KND95762.1 - 5.5e-10 39.8 1.1 1.1e-09 38.8 0.1 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KND95762.1 - 4.8e-05 23.9 0.2 2.4 8.8 0.0 4.0 3 1 0 3 3 3 2 Aspartyl protease PmbA_TldD PF01523.16 KND95762.1 - 0.026 14.4 0.2 0.054 13.3 0.2 1.4 1 0 0 1 1 1 0 Putative modulator of DNA gyrase PEX11 PF05648.14 KND95763.1 - 2.1e-46 158.2 0.7 2.3e-46 158.0 0.7 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Spc7 PF08317.11 KND95764.1 - 1.1e-62 211.7 18.5 1.1e-62 211.7 18.5 3.1 3 0 0 3 3 3 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 KND95764.1 - 9.5e-07 28.8 0.1 4e-06 26.8 0.1 2.0 1 0 0 1 1 1 1 Spc7_C2 RRF_GI PF12614.8 KND95764.1 - 0.12 12.5 8.0 0.29 11.3 6.3 2.5 1 1 1 2 2 2 0 Ribosome recycling factor TPR_1 PF00515.28 KND95766.1 - 2.3e-19 68.3 18.8 0.0052 16.6 0.0 14.2 15 1 0 15 15 15 3 Tetratricopeptide repeat TPR_2 PF07719.17 KND95766.1 - 3.2e-19 67.4 29.2 0.00016 21.5 0.1 14.6 16 1 0 16 16 15 3 Tetratricopeptide repeat TPR_8 PF13181.6 KND95766.1 - 4.2e-19 67.1 34.1 0.013 15.6 0.0 15.2 15 1 0 15 15 15 4 Tetratricopeptide repeat TPR_16 PF13432.6 KND95766.1 - 2.1e-16 60.2 4.3 9e-07 29.4 0.2 6.8 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KND95766.1 - 3.1e-15 55.6 17.6 0.033 15.0 0.2 12.1 9 3 4 13 13 11 3 Tetratricopeptide repeat TPR_6 PF13174.6 KND95766.1 - 5e-14 51.9 16.3 0.069 13.8 0.1 11.7 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_12 PF13424.6 KND95766.1 - 1e-12 48.2 23.6 0.034 14.5 0.0 11.5 9 3 3 12 12 11 3 Tetratricopeptide repeat TPR_19 PF14559.6 KND95766.1 - 1.3e-12 48.1 28.7 8.7e-06 26.2 0.4 10.3 9 2 2 11 11 10 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KND95766.1 - 1.3e-08 34.9 22.4 0.023 14.9 0.1 7.3 5 2 2 7 7 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KND95766.1 - 2.1e-08 33.7 22.0 0.015 15.0 0.1 10.0 11 1 1 12 12 12 2 TPR repeat TPR_17 PF13431.6 KND95766.1 - 3.2e-06 27.2 17.6 4.7 7.8 0.0 11.4 13 0 0 13 13 11 1 Tetratricopeptide repeat TPR_7 PF13176.6 KND95766.1 - 3.5e-06 26.7 15.5 0.58 10.3 0.0 9.9 12 1 1 13 13 12 1 Tetratricopeptide repeat TPR_9 PF13371.6 KND95766.1 - 5.8e-06 26.4 10.4 0.063 13.4 0.0 6.5 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 KND95766.1 - 0.00075 19.3 10.1 0.47 10.4 0.1 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat FIVAR PF07554.13 KND95766.1 - 0.055 14.2 5.9 0.71 10.7 0.1 4.2 3 0 0 3 3 3 0 FIVAR domain ATC_hydrolase PF14196.6 KND95766.1 - 2.2 9.0 10.2 2.7 8.7 0.1 3.9 3 1 0 3 3 3 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Sld5 PF05916.11 KND95767.1 - 7.8e-22 77.8 0.5 1e-21 77.5 0.5 1.1 1 0 0 1 1 1 1 GINS complex protein TPR_17 PF13431.6 KND95767.1 - 0.26 11.7 1.3 0.4 11.2 0.0 1.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_PK PF05891.12 KND95769.1 - 3.5e-79 265.3 0.0 4.1e-79 265.1 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KND95769.1 - 0.017 15.8 0.0 0.043 14.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 KND95769.1 - 0.12 11.7 0.0 0.3 10.4 0.0 1.7 1 0 0 1 1 1 0 O-methyltransferase domain ThiF PF00899.21 KND95770.1 - 1.4e-46 158.8 0.1 3.2e-46 157.7 0.0 1.5 2 0 0 2 2 2 1 ThiF family Sacchrp_dh_NADP PF03435.18 KND95770.1 - 0.00039 20.7 5.7 0.0015 18.8 1.9 3.1 3 1 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KND95770.1 - 0.0043 17.1 0.1 0.0087 16.1 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KND95770.1 - 0.016 15.4 0.3 0.15 12.3 0.1 2.4 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_7 PF13241.6 KND95770.1 - 0.06 13.8 0.1 0.28 11.6 0.1 2.2 2 1 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KND95770.1 - 0.071 12.7 0.4 0.14 11.7 0.4 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PglD_N PF17836.1 KND95770.1 - 0.11 13.2 0.8 0.35 11.5 0.1 2.2 2 0 0 2 2 2 0 PglD N-terminal domain DUF1279 PF06916.13 KND95771.1 - 4.4e-26 91.2 0.0 7.2e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Mito_carr PF00153.27 KND95772.1 - 8.7e-60 198.7 0.9 6.5e-21 74.1 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KND95772.1 - 0.007 15.6 0.0 0.7 9.0 0.0 2.2 2 0 0 2 2 2 2 Gammaproteobacterial serine protease Abhydrolase_1 PF00561.20 KND95773.1 - 1.5e-27 96.8 0.2 2.9e-27 96.0 0.2 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KND95773.1 - 2.1e-25 89.4 0.2 4.9e-25 88.2 0.2 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KND95773.1 - 1.8e-19 71.2 0.0 2.2e-19 71.0 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KND95773.1 - 1.4e-06 28.0 0.2 0.0022 17.5 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF915 PF06028.11 KND95773.1 - 0.00015 21.2 0.0 0.0038 16.6 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_2 PF02230.16 KND95773.1 - 0.00035 20.5 0.0 0.00067 19.5 0.0 1.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 KND95773.1 - 0.0015 18.3 0.0 0.92 9.2 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF1749 PF08538.10 KND95773.1 - 0.0035 16.5 0.0 0.36 9.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) AXE1 PF05448.12 KND95773.1 - 0.036 12.8 0.0 5.3 5.6 0.0 2.3 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_4 PF08386.10 KND95773.1 - 0.036 14.2 0.0 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 TAP-like protein Ndr PF03096.14 KND95773.1 - 0.069 11.8 0.0 0.08 11.6 0.0 1.2 1 0 0 1 1 1 0 Ndr family FSH1 PF03959.13 KND95773.1 - 0.085 12.5 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.18 KND95773.1 - 0.17 11.4 0.0 0.42 10.1 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family NDT80_PhoG PF05224.12 KND95775.1 - 9.1e-55 185.8 0.1 1.7e-54 184.9 0.1 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family RhoGAP PF00620.27 KND95779.1 - 2.2e-34 118.5 3.7 1e-20 74.1 0.0 2.7 3 0 0 3 3 3 2 RhoGAP domain Leo1 PF04004.13 KND95780.1 - 1.1e-42 145.7 0.5 1.1e-42 145.7 0.5 2.3 2 0 0 2 2 2 1 Leo1-like protein HUN PF08729.10 KND95780.1 - 0.38 10.8 10.0 1.3 9.0 10.0 2.0 1 0 0 1 1 1 0 HPC2 and ubinuclein domain ADK PF00406.22 KND95781.1 - 8e-43 146.1 0.0 1e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KND95781.1 - 4.1e-20 72.6 0.0 7.5e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 KND95781.1 - 5.6e-11 42.2 0.0 9e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KND95781.1 - 2.3e-06 28.2 0.0 3.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KND95781.1 - 0.031 14.4 1.6 0.11 12.7 0.3 2.2 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KND95781.1 - 0.039 13.3 0.1 0.059 12.8 0.1 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ADK PF00406.22 KND95783.1 - 2.7e-31 108.7 0.0 3.2e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.14 KND95783.1 - 7.7e-14 51.4 0.0 1.3e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 KND95783.1 - 4.7e-12 46.5 0.0 7.1e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KND95783.1 - 0.0002 21.9 0.0 0.00036 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KND95783.1 - 0.0057 16.8 0.0 0.017 15.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KND95783.1 - 0.023 14.4 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KND95783.1 - 0.024 14.9 0.1 0.059 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KND95783.1 - 0.045 14.0 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KND95783.1 - 0.045 13.0 0.0 0.083 12.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.22 KND95783.1 - 0.12 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.18 KND95783.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 KND95783.1 - 0.16 12.4 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DEAD_2 PF06733.15 KND95784.1 - 1.2e-54 184.6 0.5 1.2e-54 184.6 0.5 1.9 3 0 0 3 3 3 1 DEAD_2 HBB PF06777.11 KND95784.1 - 4.4e-48 163.5 2.9 8.1e-44 149.6 0.9 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KND95784.1 - 2.7e-43 148.1 0.0 1e-42 146.2 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 KND95784.1 - 0.00031 20.8 0.5 0.18 11.8 0.0 2.7 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit DEAD PF00270.29 KND95784.1 - 0.0012 18.7 0.0 0.31 10.8 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Actin PF00022.19 KND95785.1 - 6.3e-07 28.3 0.0 0.00035 19.3 0.0 2.9 2 1 1 3 3 3 2 Actin DHOR PF06537.11 KND95785.1 - 0.11 11.1 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Di-haem oxidoreductase, putative peroxidase BAR PF03114.18 KND95787.1 - 1.4e-54 185.2 3.0 1.7e-54 185.0 3.0 1.0 1 0 0 1 1 1 1 BAR domain Jnk-SapK_ap_N PF09744.9 KND95787.1 - 0.041 14.1 0.5 0.041 14.1 0.5 1.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 HAUS-augmin3 PF14932.6 KND95787.1 - 0.14 11.7 1.3 0.19 11.3 0.5 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4164 PF13747.6 KND95787.1 - 0.86 9.9 6.9 0.11 12.7 0.8 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) AAA PF00004.29 KND95791.1 - 3.2e-40 137.6 0.0 5.8e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KND95791.1 - 1.7e-07 30.9 0.0 4.1e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KND95791.1 - 4.8e-05 23.4 0.0 0.0002 21.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KND95791.1 - 6.7e-05 23.2 0.0 0.0027 18.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KND95791.1 - 0.00017 22.0 0.2 0.0041 17.5 0.0 2.4 2 1 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 KND95791.1 - 0.00037 20.7 0.0 0.00076 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KND95791.1 - 0.00088 18.5 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KND95791.1 - 0.0043 16.8 0.0 0.0087 15.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KND95791.1 - 0.012 15.9 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KND95791.1 - 0.017 14.6 0.0 0.047 13.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KND95791.1 - 0.017 15.5 0.0 0.082 13.3 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 KND95791.1 - 0.022 14.1 0.0 0.1 11.9 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KND95791.1 - 0.024 14.5 0.0 0.087 12.7 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KND95791.1 - 0.028 15.0 0.0 0.074 13.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 KND95791.1 - 0.028 14.6 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KND95791.1 - 0.032 13.9 0.1 0.085 12.6 0.1 1.8 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KND95791.1 - 0.039 13.9 0.0 5.2 6.9 0.0 2.4 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 KND95791.1 - 0.041 13.1 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 KND95791.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 KND95791.1 - 0.15 11.8 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_pol_Rbc25 PF08292.12 KND95792.1 - 1.2e-45 154.9 0.6 2.4e-45 153.9 0.6 1.5 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KND95792.1 - 3.5e-14 52.9 0.0 5.7e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KND95792.1 - 0.17 12.3 0.0 0.42 11.0 0.0 1.8 1 1 0 1 1 1 0 S1 RNA binding domain RRM_1 PF00076.22 KND95793.1 - 1.2e-19 69.8 0.1 1.7e-19 69.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KND95793.1 - 0.073 13.2 0.1 0.25 11.5 0.1 2.0 2 1 0 2 2 2 0 RNA recognition motif TMEM223 PF14640.6 KND95794.1 - 4e-05 23.9 0.0 6.4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 223 DUF3961 PF13106.6 KND95794.1 - 0.072 12.7 0.6 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3961) Matrilin_ccoil PF10393.9 KND95795.1 - 0.068 13.0 0.0 0.074 12.9 0.0 1.1 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin HLH PF00010.26 KND95796.1 - 2.6e-11 43.3 0.5 6e-11 42.1 0.5 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF1897 PF09005.10 KND95797.1 - 0.032 13.7 0.1 0.043 13.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) RTC4 PF14474.6 KND95799.1 - 2.6e-24 85.7 0.0 2.6e-24 85.7 0.0 1.8 2 0 0 2 2 2 1 RTC4-like domain Pterin_bind PF00809.22 KND95800.1 - 5.7e-65 219.4 0.0 1.5e-62 211.5 0.0 2.4 1 1 0 1 1 1 1 Pterin binding enzyme FolB PF02152.18 KND95800.1 - 8.6e-33 113.2 0.1 2.7e-19 69.7 0.2 2.6 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.20 KND95800.1 - 2.5e-30 105.3 0.1 8.6e-30 103.5 0.0 2.0 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) RRM_1 PF00076.22 KND95801.1 - 7e-13 48.2 0.1 1.6e-12 47.1 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.21 KND95801.1 - 0.0014 18.9 0.0 0.0024 18.2 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_5 PF13893.6 KND95801.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KND95801.1 - 0.066 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 RRM-like domain adh_short_C2 PF13561.6 KND95802.1 - 1e-60 205.2 0.2 1.2e-60 205.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND95802.1 - 4.6e-44 150.2 1.0 5.5e-44 150.0 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND95802.1 - 3.7e-12 46.5 0.7 5.7e-12 45.9 0.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KND95802.1 - 2e-06 27.5 1.1 1.2e-05 24.9 1.1 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KND95802.1 - 1.3e-05 24.3 0.3 1.8e-05 23.9 0.3 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KND95802.1 - 0.00089 18.7 1.3 0.0032 16.9 0.1 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 KND95802.1 - 0.0075 16.8 0.0 0.016 15.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KND95802.1 - 0.018 14.9 0.1 0.028 14.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KND95802.1 - 0.037 13.1 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DFP PF04127.15 KND95802.1 - 0.065 13.0 0.2 0.13 12.1 0.2 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein FLgD_tudor PF13861.6 KND95802.1 - 0.094 13.0 0.3 0.76 10.1 0.0 2.2 2 0 0 2 2 2 0 FlgD Tudor-like domain Glyco_hydro_63 PF03200.16 KND95803.1 - 1e-08 34.4 2.3 1.8e-05 23.7 0.4 3.6 2 1 0 2 2 2 2 Glycosyl hydrolase family 63 C-terminal domain V-SNARE PF05008.15 KND95804.1 - 9.2e-19 67.6 6.2 9.2e-19 67.6 6.2 2.6 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KND95804.1 - 1.7e-17 63.4 4.4 1.7e-17 63.4 4.4 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Use1 PF09753.9 KND95804.1 - 0.0005 19.9 8.0 0.00079 19.2 8.0 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 Sec20 PF03908.13 KND95804.1 - 0.017 15.0 1.9 0.02 14.8 0.6 1.8 1 1 0 1 1 1 0 Sec20 YqjK PF13997.6 KND95804.1 - 0.078 13.2 0.1 0.078 13.2 0.1 3.4 4 1 0 4 4 4 0 YqjK-like protein EMC3_TMCO1 PF01956.16 KND95804.1 - 0.084 12.6 0.0 0.35 10.6 0.0 2.1 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like MRP-S26 PF14943.6 KND95804.1 - 0.46 10.4 10.3 0.23 11.3 8.2 1.5 1 1 0 1 1 1 0 Mitochondrial ribosome subunit S26 V-ATPase_G_2 PF16999.5 KND95804.1 - 2.1 8.8 10.0 0.46 10.9 5.0 2.4 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF1640 PF07798.11 KND95804.1 - 2.8 7.9 13.7 78 3.2 13.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Fer2 PF00111.27 KND95805.1 - 1.2e-14 54.0 0.3 1.6e-14 53.6 0.3 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain LysM PF01476.20 KND95805.1 - 0.21 11.7 0.0 0.45 10.6 0.0 1.5 2 0 0 2 2 2 0 LysM domain Phage_tail_T PF06223.12 KND95807.1 - 0.09 13.3 0.1 0.09 13.3 0.1 1.0 1 0 0 1 1 1 0 Minor tail protein T DUF4971 PF16341.5 KND95808.1 - 0.11 12.4 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4971) DUF4407 PF14362.6 KND95808.1 - 0.45 9.8 31.0 4.7 6.5 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) KASH_CCD PF14662.6 KND95808.1 - 6.4 6.5 56.9 0.033 14.0 30.5 3.3 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH SAGA-Tad1 PF12767.7 KND95809.1 - 3.3e-55 187.4 3.8 4.9e-55 186.8 3.8 1.3 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.14 KND95809.1 - 1e-06 28.8 0.0 1.8e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family MFS_1 PF07690.16 KND95811.1 - 1.3e-35 123.0 59.7 3e-33 115.2 60.2 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Stevor PF17410.2 KND95811.1 - 4.8 6.7 6.5 1.4 8.4 0.2 2.2 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame DUF5588 PF17826.1 KND95814.1 - 0.15 10.9 0.0 0.15 10.9 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5588) ATP-synt_J PF04911.12 KND95819.1 - 5.1e-08 32.4 0.1 5.5e-08 32.3 0.1 1.1 1 0 0 1 1 1 1 ATP synthase j chain Methyltransf_16 PF10294.9 KND95821.1 - 7.2e-17 61.7 0.0 1.1e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_2 PF00891.18 KND95821.1 - 0.00047 19.5 0.0 0.00073 18.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KND95821.1 - 0.0019 18.9 0.0 0.0037 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND95821.1 - 0.01 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KND95821.1 - 0.027 14.2 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KND95821.1 - 0.13 13.1 0.0 0.23 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Allantoicase PF03561.15 KND95822.1 - 6.4e-87 288.8 0.0 2.7e-42 144.2 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat JIP_LZII PF16471.5 KND95825.1 - 0.92 9.7 12.7 0.98 9.6 3.1 3.3 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II Flagellin_N PF00669.20 KND95825.1 - 1.3 9.2 6.2 0.86 9.7 0.9 3.0 3 0 0 3 3 3 0 Bacterial flagellin N-terminal helical region Baculo_PEP_C PF04513.12 KND95825.1 - 2.4 8.2 6.7 0.39 10.8 0.3 2.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lzipper-MIP1 PF14389.6 KND95825.1 - 5 7.5 20.9 0.42 10.9 5.0 3.9 4 0 0 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 T3SS_needle_E PF08988.10 KND95827.1 - 0.067 13.4 0.1 0.083 13.0 0.1 1.1 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle HTH_Tnp_Tc5 PF03221.16 KND95830.1 - 6.2e-13 48.6 0.1 1.3e-12 47.6 0.1 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain VitK2_biosynth PF02621.14 KND95830.1 - 0.11 12.0 0.3 0.21 11.1 0.3 1.4 1 0 0 1 1 1 0 Menaquinone biosynthesis tRNA_m1G_MT PF01746.21 KND95832.1 - 1.5e-29 103.1 0.0 1.5e-29 103.1 0.0 1.4 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase RRP36 PF06102.12 KND95832.1 - 1.1 9.2 11.0 16 5.4 6.4 2.8 2 1 1 3 3 3 0 rRNA biogenesis protein RRP36 NARP1 PF12569.8 KND95832.1 - 3.7 6.3 6.9 4 6.2 4.7 1.9 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Zn_clus PF00172.18 KND95833.1 - 9.5e-09 35.2 12.7 1.9e-08 34.3 12.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND95833.1 - 3.6e-07 29.5 0.1 3.6e-07 29.5 0.1 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain PQ-loop PF04193.14 KND95834.1 - 6.6e-40 134.7 18.8 4.8e-22 77.5 1.6 2.9 3 0 0 3 3 3 2 PQ loop repeat AMP-binding PF00501.28 KND95835.1 - 4.9e-63 213.2 0.0 2.6e-62 210.8 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme tRNA_int_end_N2 PF12928.7 KND95837.1 - 9.7e-18 64.1 0.0 2.1e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term CBM_11 PF03425.13 KND95837.1 - 0.0064 16.4 0.4 0.028 14.3 0.2 2.0 2 0 0 2 2 2 1 Carbohydrate binding domain (family 11) tRNA_int_endo_N PF02778.14 KND95837.1 - 0.072 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain SAPS PF04499.15 KND95838.1 - 0.044 12.6 0.3 0.078 11.8 0.3 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Smg4_UPF3 PF03467.15 KND95839.1 - 1.6e-22 80.3 0.1 1.6e-22 80.3 0.1 3.1 1 1 1 2 2 2 1 Smg-4/UPF3 family PCI PF01399.27 KND95840.1 - 0.00021 21.8 0.1 0.0022 18.5 0.0 2.8 3 1 0 3 3 3 1 PCI domain INSIG PF07281.12 KND95842.1 - 0.089 12.4 0.0 0.098 12.3 0.0 1.1 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) Ferric_reduct PF01794.19 KND95843.1 - 6.2e-16 58.7 10.2 6.2e-16 58.7 10.2 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KND95843.1 - 0.0013 18.9 0.0 0.07 13.2 0.0 2.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain zf-CCHC PF00098.23 KND95845.1 - 0.003 17.6 1.3 0.003 17.6 1.3 5.5 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_3 PF13917.6 KND95845.1 - 0.03 14.3 1.0 0.03 14.3 1.0 5.5 3 1 3 6 6 6 0 Zinc knuckle zf-CCHC_5 PF14787.6 KND95845.1 - 6.1 6.7 32.0 1.2 8.9 2.3 4.8 2 1 2 4 4 4 0 GAG-polyprotein viral zinc-finger Cg6151-P PF10233.9 KND95846.1 - 4.2e-42 143.0 14.2 5.7e-42 142.6 14.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Comm PF15957.5 KND95846.1 - 0.15 12.5 0.1 0.15 12.5 0.1 2.3 2 0 0 2 2 2 0 Commissureless YwiC PF14256.6 KND95846.1 - 1.7 9.0 10.1 0.9 9.9 3.5 2.1 1 1 0 2 2 2 0 YwiC-like protein DUF5592 PF17332.2 KND95846.1 - 5.8 7.5 9.2 0.75 10.4 3.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5592) MMR_HSR1_C PF08438.10 KND95847.1 - 1.1e-34 119.4 0.0 1.7e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KND95847.1 - 5.9e-21 74.7 0.0 2.2e-20 72.9 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KND95847.1 - 1.4e-08 34.4 0.7 1.1e-06 28.2 0.1 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B ABC_tran PF00005.27 KND95847.1 - 0.0058 17.1 0.1 0.13 12.8 0.1 2.3 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 KND95847.1 - 0.0059 16.5 2.4 0.21 11.5 0.1 2.6 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 KND95847.1 - 0.0077 15.8 5.0 0.19 11.2 0.1 3.1 4 1 0 4 4 4 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 KND95847.1 - 0.0096 14.9 0.9 0.024 13.6 0.1 2.0 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KND95847.1 - 0.011 15.8 0.1 0.029 14.4 0.0 1.7 2 0 0 2 2 2 0 Dynamin family ATP_bind_1 PF03029.17 KND95847.1 - 0.012 15.4 0.4 3.1 7.5 0.1 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 KND95847.1 - 0.082 13.2 0.5 0.17 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KND95847.1 - 0.1 12.9 0.2 1.5 9.1 0.0 2.5 2 1 1 3 3 3 0 AAA domain CRAL_TRIO PF00650.20 KND95848.1 - 1.1e-18 67.4 0.0 1.7e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KND95848.1 - 3.3e-07 30.4 1.2 7.2e-07 29.3 0.1 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain DUF3877 PF12993.7 KND95848.1 - 0.053 13.4 0.4 0.091 12.6 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) DnaJ PF00226.31 KND95849.1 - 6.9e-23 80.6 1.4 1.7e-22 79.3 1.4 1.7 1 0 0 1 1 1 1 DnaJ domain GBP_C PF02841.14 KND95849.1 - 0.014 14.8 16.4 0.025 14.0 16.4 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain PilM PF07419.12 KND95849.1 - 0.038 14.2 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 PilM Spore_III_AF PF09581.10 KND95849.1 - 2.4 8.1 10.9 4.3 7.3 10.9 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Exonuc_VII_L PF02601.15 KND95849.1 - 4.8 6.7 10.5 8.6 5.8 10.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit PigN PF04987.14 KND95850.1 - 1.8e-131 439.1 46.4 3e-131 438.4 46.4 1.4 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KND95850.1 - 1.8e-11 44.3 0.9 1.2e-10 41.6 0.9 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KND95850.1 - 3.7e-07 29.8 0.1 6e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KND95850.1 - 3.4e-05 23.3 0.0 5.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily IGPS PF00218.21 KND95851.1 - 4.4e-71 239.0 0.0 6.3e-71 238.5 0.0 1.2 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 KND95851.1 - 8.8e-44 149.6 0.1 1.4e-43 148.9 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KND95851.1 - 1.7e-07 31.2 0.5 6.6e-07 29.3 0.5 1.9 1 1 0 1 1 1 1 Peptidase C26 Rep_fac-A_3 PF08661.11 KND95852.1 - 6.5e-19 68.2 0.0 7.3e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Ten1_2 PF15490.6 KND95852.1 - 0.0031 17.2 0.0 0.0077 15.9 0.0 1.7 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit tRNA_anti-codon PF01336.25 KND95852.1 - 0.043 13.8 0.4 0.38 10.8 0.4 2.1 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain PFU PF09070.11 KND95853.1 - 6e-43 145.7 0.0 2.9e-42 143.5 0.0 2.2 2 0 0 2 2 2 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 KND95853.1 - 9.8e-32 110.3 5.0 1.6e-31 109.6 5.0 1.3 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 KND95853.1 - 4.4e-27 93.8 21.2 4.9e-06 27.2 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Chorion_S16 PF05836.12 KND95853.1 - 0.046 14.0 0.0 0.35 11.1 0.0 2.3 1 1 1 2 2 2 0 Chorion protein S16 ANAPC4_WD40 PF12894.7 KND95853.1 - 0.12 12.7 0.0 0.69 10.3 0.0 2.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Syja_N PF02383.18 KND95855.1 - 1.8e-82 277.2 1.5 2.8e-82 276.6 1.5 1.3 1 0 0 1 1 1 1 SacI homology domain Cry1Ac_D5 PF17997.1 KND95855.1 - 0.093 12.6 0.2 0.67 9.8 0.0 2.2 2 0 0 2 2 2 0 Insecticidal delta-endotoxin CryIA(c) domain 5 FoP_duplication PF13865.6 KND95857.1 - 3.2e-08 34.0 5.4 5.5e-08 33.3 5.4 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.22 KND95857.1 - 0.056 13.3 0.1 0.15 11.9 0.1 1.8 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 KND95858.1 - 1.2e-33 116.5 13.7 1.2e-33 116.5 13.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TMEM234 PF10639.9 KND95858.1 - 2.7 8.0 7.5 13 5.9 0.0 3.3 4 0 0 4 4 4 0 Putative transmembrane family 234 dsrm PF00035.26 KND95859.1 - 0.00017 22.2 0.0 0.00039 21.1 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 KND95859.1 - 0.00095 19.3 0.4 0.0018 18.4 0.4 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like OAD_gamma PF04277.13 KND95859.1 - 0.074 13.7 0.2 0.18 12.4 0.2 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Mito_carr PF00153.27 KND95860.1 - 8.2e-43 144.3 7.3 1.9e-17 63.0 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Exotox-A_bind PF09101.10 KND95861.1 - 0.1 11.9 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Exotoxin A binding Mce4_CUP1 PF11887.8 KND95862.1 - 0.14 11.5 0.0 0.34 10.3 0.0 1.5 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative RNA_polI_A34 PF08208.11 KND95864.1 - 2.3e-31 109.5 24.2 3.9e-31 108.7 24.2 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Coilin_N PF15862.5 KND95864.1 - 0.014 15.2 15.3 0.021 14.6 15.3 1.3 1 0 0 1 1 1 0 Coilin N-terminus RR_TM4-6 PF06459.12 KND95864.1 - 0.038 13.8 12.1 0.044 13.6 12.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.12 KND95864.1 - 0.16 12.2 10.5 0.17 12.1 10.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Vfa1 PF08432.10 KND95864.1 - 0.19 12.1 24.2 0.31 11.4 24.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2828 PF11443.8 KND95864.1 - 0.38 8.8 10.6 0.42 8.6 10.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Presenilin PF01080.17 KND95864.1 - 0.71 8.6 5.5 0.77 8.5 5.5 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 KND95864.1 - 1.9 6.7 14.7 2.2 6.5 14.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 KND95864.1 - 4.5 6.2 6.8 5.1 6.0 6.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CPSF100_C PF13299.6 KND95864.1 - 7.3 6.8 16.0 5 7.3 14.0 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RraA-like PF03737.15 KND95867.1 - 7.9e-32 110.5 0.1 1e-31 110.1 0.1 1.1 1 0 0 1 1 1 1 Aldolase/RraA PPP4R2 PF09184.11 KND95868.1 - 0.00091 18.9 7.9 0.006 16.2 0.2 2.3 2 0 0 2 2 2 2 PPP4R2 DUF4547 PF15080.6 KND95868.1 - 0.049 13.3 0.1 0.22 11.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4547) Pkinase PF00069.25 KND95869.1 - 3.7e-71 239.6 0.0 4.8e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND95869.1 - 1.7e-39 135.6 0.0 2.4e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND95869.1 - 9.6e-06 25.1 0.1 1.9e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KND95869.1 - 0.032 13.2 0.1 0.051 12.5 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 KND95870.1 - 1.1e-33 116.8 0.0 4.3e-33 114.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND95870.1 - 1.4e-12 47.4 0.2 5.8e-12 45.4 0.2 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KND95870.1 - 0.022 14.1 0.3 0.049 13.0 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KND95873.1 - 1.2e-67 228.0 0.0 2.1e-67 227.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND95873.1 - 2.6e-52 177.7 0.0 4e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KND95873.1 - 1.5e-21 76.5 0.0 4.5e-21 75.0 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 KND95873.1 - 2.4e-06 26.6 0.0 5.1e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase PH PF00169.29 KND95873.1 - 3.2e-06 27.6 0.1 7.8e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 KND95873.1 - 3.3e-06 26.6 0.0 6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KND95873.1 - 0.00032 19.8 0.7 0.00082 18.4 0.7 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KND95873.1 - 0.0042 17.0 0.0 0.0087 16.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KND95873.1 - 0.022 13.9 0.1 0.035 13.2 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 KND95873.1 - 0.022 14.3 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KND95873.1 - 0.05 12.9 0.1 0.09 12.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gti1_Pac2 PF09729.9 KND95875.1 - 1.1e-45 156.0 0.2 5.8e-45 153.6 0.2 2.1 1 1 0 1 1 1 1 Gti1/Pac2 family F-box-like PF12937.7 KND95882.1 - 8.2e-06 25.6 0.0 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KND95882.1 - 0.058 13.3 0.0 0.22 11.4 0.0 2.1 1 0 0 1 1 1 0 F-box domain TFA2_Winged_2 PF18121.1 KND95884.1 - 1.6e-21 75.8 0.2 3.9e-21 74.5 0.1 1.8 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KND95884.1 - 4.3e-17 62.2 0.2 1.6e-16 60.3 0.1 2.1 2 0 0 2 2 2 1 TFIIE beta subunit core domain NTF2 PF02136.20 KND95885.1 - 8.9e-24 84.4 0.0 9.8e-24 84.2 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain KH_1 PF00013.29 KND95886.1 - 0.15 11.9 0.2 0.5 10.2 0.2 1.9 1 0 0 1 1 1 0 KH domain cwf21 PF08312.12 KND95887.1 - 1.6e-12 47.3 14.7 1.6e-12 47.3 14.7 2.5 2 0 0 2 2 2 1 cwf21 domain RGS-like PF09128.11 KND95887.1 - 2.7 7.6 12.9 3.6 7.3 12.9 1.2 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain His_Phos_2 PF00328.22 KND95889.1 - 8.7e-12 45.1 0.1 0.00011 21.7 0.0 2.5 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) EamA PF00892.20 KND95892.1 - 3.5e-28 98.5 27.8 1.9e-18 66.9 4.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KND95892.1 - 0.0023 17.3 1.4 0.005 16.2 1.4 1.5 1 0 0 1 1 1 1 Triose-phosphate Transporter family SLC35F PF06027.12 KND95892.1 - 0.0074 15.8 5.9 0.036 13.6 5.8 2.1 1 1 0 1 1 1 1 Solute carrier family 35 Gaa1 PF04114.14 KND95892.1 - 1.2 8.1 6.2 0.98 8.4 1.8 2.0 1 1 1 2 2 2 0 Gaa1-like, GPI transamidase component PUFD PF16553.5 KND95894.1 - 0.053 13.6 0.0 0.19 11.9 0.0 1.9 1 1 0 1 1 1 0 BCORL-PCGF1-binding domain 4HBT PF03061.22 KND95895.1 - 5.9e-07 29.7 0.0 1e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Asn_synthase PF00733.21 KND95896.1 - 7.9e-16 58.7 1.0 1.9e-10 41.0 0.6 3.3 2 1 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KND95896.1 - 4e-13 49.3 0.0 1.3e-12 47.7 0.0 1.9 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KND95896.1 - 1.9e-07 31.3 0.0 1.1e-06 28.9 0.0 2.3 2 1 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KND95896.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Aluminium induced protein Glyco_hydro_31 PF01055.26 KND95897.1 - 2.9e-151 504.6 4.6 3.8e-151 504.2 4.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KND95897.1 - 3e-24 85.5 0.1 5.6e-24 84.6 0.1 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Rotavirus_VP7 PF05868.11 KND95897.1 - 0.0067 15.8 0.1 0.019 14.4 0.1 1.7 1 0 0 1 1 1 1 Rotavirus major outer capsid protein VP7 ANAPC_CDC26 PF10471.9 KND95898.1 - 7.7e-09 36.3 0.1 1e-08 35.8 0.1 1.3 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 U3_snoRNA_assoc PF08297.11 KND95899.1 - 8.8e-17 61.6 11.8 8.8e-17 61.6 11.8 2.8 2 1 0 2 2 2 1 U3 snoRNA associated CHAD PF05235.14 KND95899.1 - 0.91 9.4 14.5 1.2 9.1 14.5 1.2 1 0 0 1 1 1 0 CHAD domain F-box-like PF12937.7 KND95900.1 - 2.4e-10 40.1 0.8 7.5e-10 38.6 0.4 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KND95900.1 - 6.3e-08 32.3 0.6 2e-07 30.7 0.6 1.9 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.28 KND95900.1 - 6.4e-06 25.8 0.7 0.032 14.1 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KND95900.1 - 1.9e-05 24.4 0.2 0.054 13.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat LRR_6 PF13516.6 KND95900.1 - 0.02 14.9 1.0 0.22 11.7 0.1 3.3 4 0 0 4 4 4 0 Leucine Rich repeat TPR_19 PF14559.6 KND95900.1 - 0.034 14.7 0.2 1.4 9.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KND95900.1 - 0.11 12.3 0.1 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 TPR repeat TPR_12 PF13424.6 KND95900.1 - 0.11 12.8 0.0 13 6.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KND95900.1 - 0.14 12.9 1.4 1.7 9.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_4 PF12799.7 KND95900.1 - 0.94 10.0 12.0 5 7.7 0.1 6.0 5 3 1 6 6 6 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KND95900.1 - 3.1 8.7 11.5 28 5.8 0.1 5.6 5 0 0 5 5 5 0 Leucine Rich Repeat Zip PF02535.22 KND95902.1 - 5.9e-26 91.5 24.3 1.3e-19 70.6 11.0 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter SieB PF14163.6 KND95902.1 - 1.6 8.2 6.4 0.57 9.7 0.1 2.8 3 0 0 3 3 3 0 Super-infection exclusion protein B DUF3336 PF11815.8 KND95903.1 - 9.1e-34 116.1 2.9 2e-33 115.0 2.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KND95903.1 - 1.5e-21 77.6 0.1 4.5e-21 76.0 0.0 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase PLA2_B PF01735.18 KND95905.1 - 6.5e-148 493.2 0.1 7.9e-148 492.9 0.1 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.22 KND95905.1 - 0.012 15.8 0.2 0.022 14.9 0.2 1.5 1 0 0 1 1 1 0 Patatin-like phospholipase Lactamase_B_4 PF13691.6 KND95909.1 - 1.4e-16 59.9 0.2 3.2e-16 58.7 0.2 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 KND95909.1 - 5.1e-07 29.4 0.1 0.056 13.0 0.0 3.4 3 1 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KND95909.1 - 0.15 12.1 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily TPP1 PF10341.9 KND95910.1 - 2.1e-17 63.1 0.0 3.4e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD NUDIX_2 PF13869.6 KND95910.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Nucleotide hydrolase Phosphatase PF15698.5 KND95912.1 - 0.044 12.9 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 Phosphatase Ribosomal_L2_C PF03947.18 KND95913.1 - 2e-51 173.4 3.1 4.2e-51 172.4 3.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KND95913.1 - 2.2e-24 85.2 2.2 9.6e-24 83.1 0.2 2.6 3 0 0 3 3 3 1 Ribosomal Proteins L2, RNA binding domain Prot_ATP_ID_OB PF16450.5 KND95913.1 - 0.033 14.1 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain OSCP PF00213.18 KND95914.1 - 4.4e-46 157.1 1.8 5.2e-46 156.9 1.8 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit AhpC-TSA PF00578.21 KND95916.1 - 5.5e-27 94.1 0.0 7.6e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KND95916.1 - 1.9e-19 69.8 0.0 2.8e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KND95916.1 - 0.0041 17.2 0.0 0.0058 16.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme CDC45 PF02724.14 KND95916.1 - 0.13 10.5 7.1 0.15 10.4 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Mito_carr PF00153.27 KND95923.1 - 1e-62 208.1 4.9 8.1e-22 77.0 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KND95923.1 - 4.4e-22 75.9 17.9 2.5e-05 23.5 0.5 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KND95923.1 - 4.4e-21 75.1 13.4 1.8e-11 44.3 1.8 4.3 2 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 KND95923.1 - 2.8e-20 70.4 18.7 0.00013 21.6 0.2 4.7 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KND95923.1 - 3.8e-19 68.3 9.2 0.00016 21.4 0.1 4.7 4 1 1 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 KND95923.1 - 2.7e-11 42.4 18.0 0.0086 15.5 0.4 4.7 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KND95923.1 - 0.00094 19.5 1.0 0.41 11.0 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KND95923.1 - 0.0036 17.6 2.1 0.54 10.6 0.2 2.5 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region p25-alpha PF05517.12 KND95923.1 - 0.13 12.4 4.8 12 6.0 0.4 3.4 1 1 3 4 4 4 0 p25-alpha SinI PF08671.10 KND95923.1 - 0.2 11.5 1.1 6.9 6.6 0.1 2.5 2 0 0 2 2 2 0 Anti-repressor SinI Dockerin_1 PF00404.18 KND95923.1 - 2.6 8.3 7.1 5.9e+02 0.8 7.3 3.3 2 1 0 2 2 2 0 Dockerin type I domain HORMA PF02301.18 KND95924.1 - 1.8e-05 24.4 0.1 2.6e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 HORMA domain MutL_C PF08676.11 KND95925.1 - 5.6e-29 100.8 0.2 1.2e-28 99.7 0.2 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KND95925.1 - 6.6e-22 77.4 0.1 1.9e-21 76.0 0.0 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KND95925.1 - 5.1e-11 42.5 0.1 1.3e-10 41.2 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KND95925.1 - 1.5e-05 25.5 0.0 3.6e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Dimer_Tnp_Tn5 PF02281.16 KND95926.1 - 0.049 13.3 0.3 0.16 11.7 0.3 1.7 1 1 0 1 1 1 0 Transposase Tn5 dimerisation domain Zn_clus PF00172.18 KND95927.1 - 3.8e-07 30.1 9.2 6.7e-07 29.3 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KND95928.1 - 1.8e-08 34.4 7.3 2.8e-08 33.7 7.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain N2227 PF07942.12 KND95929.1 - 3.9e-79 265.6 0.0 4.8e-79 265.4 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 KND95929.1 - 0.0011 18.9 0.0 0.0021 17.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND95929.1 - 0.0052 17.4 0.1 0.14 12.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND95929.1 - 0.013 16.2 0.0 0.065 14.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DUF4864 PF16156.5 KND95929.1 - 0.054 14.2 0.0 4.7 8.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4864) Methyltransf_25 PF13649.6 KND95929.1 - 0.13 13.0 0.0 9.8 7.0 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Ras PF00071.22 KND95930.1 - 7.7e-60 201.2 0.1 9e-60 200.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND95930.1 - 3.1e-34 117.8 0.0 4.5e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND95930.1 - 1e-14 54.4 0.0 1.1e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KND95930.1 - 1.6e-06 27.6 0.0 2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KND95930.1 - 1.6e-05 25.0 0.0 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KND95930.1 - 2.3e-05 24.4 0.2 0.063 13.2 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KND95930.1 - 0.0001 21.9 0.0 0.00018 21.1 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KND95930.1 - 0.0002 21.8 0.1 0.00029 21.3 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain Phage_sheath_1N PF17481.2 KND95930.1 - 0.03 14.8 0.3 0.046 14.2 0.3 1.5 1 1 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain Rep_1 PF01446.17 KND95930.1 - 0.13 11.7 0.1 0.17 11.3 0.1 1.1 1 0 0 1 1 1 0 Replication protein NMT1 PF09084.11 KND95931.1 - 4.6e-21 75.8 0.1 1.8e-20 73.9 0.1 1.8 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 KND95931.1 - 1.5e-05 24.6 0.0 3e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.6 KND95931.1 - 0.00013 21.8 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 KND95931.1 - 0.00017 21.2 0.0 0.00041 20.0 0.0 1.5 2 0 0 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein VitK2_biosynth PF02621.14 KND95931.1 - 0.00055 19.5 0.0 0.00074 19.1 0.0 1.2 1 0 0 1 1 1 1 Menaquinone biosynthesis LysR_substrate PF03466.20 KND95931.1 - 0.0037 16.7 0.0 0.22 10.9 0.0 2.2 2 0 0 2 2 2 1 LysR substrate binding domain DUF3834 PF12916.7 KND95931.1 - 0.089 12.0 0.0 0.28 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3834) Octopine_DH PF02317.17 KND95931.1 - 0.11 12.5 0.0 0.4 10.8 0.0 1.8 2 0 0 2 2 2 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Y_phosphatase PF00102.27 KND95932.1 - 3.6e-55 187.1 0.0 5.6e-55 186.5 0.0 1.3 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KND95932.1 - 0.0026 17.6 0.0 0.0042 16.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KND95932.1 - 0.022 14.9 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KND95932.1 - 0.097 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family KH_1 PF00013.29 KND95933.1 - 1.3e-11 44.1 0.1 2.6e-11 43.2 0.1 1.5 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 KND95933.1 - 0.032 14.1 0.2 0.057 13.2 0.2 1.4 1 0 0 1 1 1 0 KH domain PFU PF09070.11 KND95933.1 - 0.16 12.2 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) HSP70 PF00012.20 KND95934.1 - 2.1e-229 762.7 7.5 2.6e-229 762.4 7.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KND95934.1 - 1.8e-17 63.1 0.1 5.7e-16 58.2 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KND95934.1 - 0.00052 19.8 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain ATP-synt_DE PF00401.20 KND95934.1 - 0.0073 16.5 2.5 0.069 13.4 1.1 2.8 2 0 0 2 2 2 1 ATP synthase, Delta/Epsilon chain, long alpha-helix domain RIO1 PF01163.22 KND95935.1 - 3.3e-44 150.8 0.1 6.1e-44 149.9 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KND95935.1 - 2.6e-30 104.5 0.1 1.6e-29 102.0 0.0 2.2 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 KND95935.1 - 3.8e-06 27.0 0.1 0.023 14.6 0.2 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KND95935.1 - 0.00011 21.7 0.0 0.0076 15.6 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_8 PF13855.6 KND95937.1 - 0.11 12.3 0.5 0.35 10.7 0.5 1.9 1 1 0 1 1 1 0 Leucine rich repeat LRR_6 PF13516.6 KND95937.1 - 0.14 12.2 1.5 0.34 11.1 0.6 2.1 2 0 0 2 2 2 0 Leucine Rich repeat DCP2 PF05026.13 KND95938.1 - 8.8e-26 90.1 0.0 2e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KND95938.1 - 2.1e-13 50.4 0.0 6e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain ATP-synt_10 PF05176.14 KND95939.1 - 3.7e-80 268.9 0.0 4.3e-80 268.7 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein PQQ PF01011.21 KND95939.1 - 0.0073 16.2 0.1 0.023 14.6 0.0 1.9 2 0 0 2 2 2 1 PQQ enzyme repeat Ribosomal_S10 PF00338.22 KND95940.1 - 1.4e-26 92.6 0.5 1.8e-26 92.2 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e fn3_5 PF06280.12 KND95940.1 - 0.22 12.2 1.6 0.77 10.5 0.1 1.9 1 1 1 2 2 2 0 Fn3-like domain DUF1667 PF07892.11 KND95940.1 - 0.81 9.8 5.9 0.59 10.2 1.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1667) PP2C PF00481.21 KND95942.1 - 1.6e-43 149.2 0.0 3e-43 148.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C DSHCT PF08148.12 KND95943.1 - 1.3e-49 168.0 0.8 4e-49 166.4 0.8 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 KND95943.1 - 3e-37 127.4 0.7 2.7e-36 124.3 0.2 2.6 3 0 0 3 3 3 1 Ski2 N-terminal region DEAD PF00270.29 KND95943.1 - 7.8e-20 71.4 0.6 3.5e-19 69.2 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.6 KND95943.1 - 7.2e-16 58.9 7.1 7.2e-16 58.9 7.1 2.3 2 0 0 2 2 2 1 rRNA-processing arch domain Helicase_C PF00271.31 KND95943.1 - 8.2e-07 29.4 0.5 5.4e-06 26.7 0.0 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain GT-D PF08759.11 KND95943.1 - 0.012 15.3 2.7 2.2 7.9 1.4 2.6 2 0 0 2 2 2 0 Glycosyltransferase GT-D fold AAA PF00004.29 KND95945.1 - 1.6e-88 293.9 0.0 8.1e-43 146.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KND95945.1 - 9.9e-23 79.7 3.3 1.6e-10 40.6 1.2 2.7 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KND95945.1 - 6.4e-14 52.0 0.0 2.8e-06 27.1 0.0 3.1 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KND95945.1 - 9.8e-12 45.6 0.2 3e-05 24.5 0.0 3.8 2 1 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 KND95945.1 - 1.7e-10 41.1 0.2 0.00022 21.2 0.0 3.4 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KND95945.1 - 3.2e-08 33.9 0.0 0.0055 16.8 0.0 3.2 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KND95945.1 - 6.5e-08 32.9 3.7 0.0027 18.0 0.0 4.9 4 2 1 5 5 4 1 AAA domain AAA_33 PF13671.6 KND95945.1 - 6e-07 29.7 0.0 0.016 15.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KND95945.1 - 7.7e-07 29.2 0.0 0.0039 17.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KND95945.1 - 1.1e-06 28.1 0.0 0.027 13.7 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain Bac_DnaA PF00308.18 KND95945.1 - 2.2e-06 27.7 0.0 0.0085 16.0 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein Rad17 PF03215.15 KND95945.1 - 6.7e-06 26.2 0.0 0.0096 15.9 0.0 2.7 2 0 0 2 2 2 2 Rad17 P-loop domain Mg_chelatase PF01078.21 KND95945.1 - 4.4e-05 23.0 0.5 0.13 11.7 0.1 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KND95945.1 - 8.5e-05 22.9 0.0 0.56 10.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase TsaE PF02367.17 KND95945.1 - 0.00036 20.5 0.1 0.3 11.1 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KND95945.1 - 0.00061 20.1 0.1 1.2 9.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 KND95945.1 - 0.00084 19.2 0.0 1 9.2 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KND95945.1 - 0.00091 19.1 0.1 0.37 10.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 KND95945.1 - 0.001 18.9 0.0 0.58 9.9 0.0 3.5 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 KND95945.1 - 0.0013 19.2 0.0 2.4 8.7 0.0 2.9 2 1 1 3 3 2 1 AAA domain IstB_IS21 PF01695.17 KND95945.1 - 0.0014 18.4 0.0 2.2 8.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 KND95945.1 - 0.0021 17.6 0.0 1.8 8.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 KND95945.1 - 0.0027 17.6 0.2 0.096 12.6 0.0 3.2 4 0 0 4 4 3 1 NACHT domain HTH_15 PF12324.8 KND95945.1 - 0.006 16.5 0.8 0.025 14.5 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of alkylmercury lyase AAA_24 PF13479.6 KND95945.1 - 0.0062 16.3 0.0 0.29 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KND95945.1 - 0.0078 15.8 1.9 1.2 8.7 0.0 3.5 2 2 0 3 3 3 1 AAA domain CDC48_N PF02359.18 KND95945.1 - 0.014 15.6 0.0 0.053 13.7 0.0 2.0 2 0 0 2 2 1 0 Cell division protein 48 (CDC48), N-terminal domain Sigma54_activ_2 PF14532.6 KND95945.1 - 0.018 15.2 0.0 0.23 11.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 KND95945.1 - 0.019 14.3 0.0 5.8 6.2 0.0 2.8 2 0 0 2 2 2 0 KaiC Sigma54_activat PF00158.26 KND95945.1 - 0.026 14.2 0.1 43 3.8 0.0 3.8 3 1 0 3 3 3 0 Sigma-54 interaction domain ABC_tran PF00005.27 KND95945.1 - 0.028 14.9 0.0 2.1 8.9 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AcetDehyd-dimer PF09290.11 KND95945.1 - 0.04 14.1 0.0 0.097 12.9 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation AAA_19 PF13245.6 KND95945.1 - 0.046 14.0 0.3 0.83 10.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KND95945.1 - 0.054 13.2 0.8 0.53 10.0 0.0 2.9 3 1 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KND95945.1 - 0.063 12.6 0.1 11 5.2 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin DUF815 PF05673.13 KND95945.1 - 0.075 12.2 0.0 6.2 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AFG1_ATPase PF03969.16 KND95945.1 - 0.12 11.3 0.1 0.5 9.2 0.0 2.0 3 0 0 3 3 3 0 AFG1-like ATPase Vps4_C PF09336.10 KND95945.1 - 0.13 12.3 0.0 1.7 8.7 0.0 2.7 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Pex19 PF04614.12 KND95946.1 - 1.9e-62 211.3 14.6 1.9e-62 211.3 14.6 2.2 1 1 1 2 2 2 1 Pex19 protein family Pup PF05639.11 KND95946.1 - 0.057 14.3 5.4 0.057 14.3 5.4 3.8 3 1 1 4 4 4 0 Pup-like protein PilJ PF13675.6 KND95946.1 - 0.12 12.4 1.5 0.58 10.2 0.1 2.5 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term RGCC PF15151.6 KND95946.1 - 0.14 12.4 0.3 0.14 12.4 0.3 2.5 1 1 0 2 2 2 0 Response gene to complement 32 protein family UQ_con PF00179.26 KND95947.1 - 1.4e-44 151.1 0.1 1.6e-44 150.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KND95947.1 - 0.00076 19.2 0.0 0.00088 19.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KND95947.1 - 0.017 15.0 0.3 0.028 14.3 0.3 1.4 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 KND95947.1 - 0.36 11.1 2.7 1.6 9.1 2.7 2.0 1 1 0 1 1 1 0 RWD domain 6PF2K PF01591.18 KND95948.1 - 9.6e-77 257.2 0.1 1.3e-76 256.8 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KND95948.1 - 1.1e-34 119.8 0.0 1.6e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KND95948.1 - 0.0014 18.8 0.0 0.0034 17.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KND95948.1 - 0.0081 15.6 0.1 0.011 15.2 0.1 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Peptidase_S64 PF08192.11 KND95949.1 - 1.3e-246 820.5 8.3 2.6e-245 816.2 8.3 2.1 1 1 0 1 1 1 1 Peptidase family S64 Flocculin_t3 PF13928.6 KND95953.1 - 0.0015 19.0 1.0 0.0015 19.0 1.0 2.6 2 1 0 2 2 2 1 Flocculin type 3 repeat F_actin_bind PF08919.10 KND95954.1 - 0.28 11.3 1.7 1.6 8.9 0.2 3.0 2 1 2 4 4 4 0 F-actin binding RbsD_FucU PF05025.13 KND95955.1 - 0.051 14.0 0.0 0.058 13.8 0.0 1.1 1 0 0 1 1 1 0 RbsD / FucU transport protein family RIBIOP_C PF04950.12 KND95957.1 - 2e-103 345.9 0.0 4.5e-103 344.7 0.0 1.6 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KND95957.1 - 1.2e-21 76.6 0.0 3.1e-21 75.3 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain zf-C2H2_2 PF12756.7 KND95958.1 - 1.7e-29 102.1 3.2 4.3e-29 100.8 3.2 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) NADH-G_4Fe-4S_3 PF10588.9 KND95958.1 - 0.61 9.7 2.7 3.6 7.2 0.4 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DnaJ_C PF01556.18 KND95960.1 - 7.5e-27 94.2 0.0 1.6e-26 93.2 0.0 1.6 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KND95960.1 - 1.4e-20 73.2 0.7 2.7e-20 72.3 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KND95960.1 - 3.2e-10 40.2 14.6 3.2e-10 40.2 14.6 2.0 2 0 0 2 2 2 1 DnaJ central domain DUF35_N PF12172.8 KND95960.1 - 0.28 11.1 7.5 1.3 9.0 0.0 2.9 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Anti-TRAP PF15777.5 KND95960.1 - 1.1 9.3 14.3 0.7 9.9 3.7 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein SUIM_assoc PF16619.5 KND95960.1 - 1.6 8.9 11.1 1.3 9.2 1.8 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 HypA PF01155.19 KND95960.1 - 4.9 7.2 9.8 3.1 7.9 0.9 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Vac14_Fig4_bd PF11916.8 KND95961.1 - 1.3e-64 217.1 10.9 3e-64 216.0 10.9 1.6 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KND95961.1 - 6.9e-35 119.5 0.5 4.2e-34 117.0 0.3 2.5 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KND95961.1 - 0.00025 21.1 1.3 0.11 12.5 0.0 3.3 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KND95961.1 - 0.0012 19.2 0.0 0.89 10.1 0.0 3.5 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.22 KND95961.1 - 0.0018 18.4 0.1 0.063 13.6 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 KND95961.1 - 0.015 15.7 0.0 1.2 9.6 0.0 3.9 3 1 1 4 4 4 0 HEAT repeats DUF4996 PF16387.5 KND95961.1 - 0.11 13.0 0.5 0.86 10.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function Pyr_redox_2 PF07992.14 KND95964.1 - 6e-11 42.1 0.0 4.8e-09 35.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KND95964.1 - 0.00087 19.3 0.0 0.0058 16.6 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KND95964.1 - 0.0069 16.9 0.7 11 6.7 0.1 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KND95964.1 - 0.007 16.6 0.0 0.2 11.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KND95964.1 - 0.086 12.1 0.9 18 4.5 0.1 3.5 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KND95964.1 - 0.19 11.8 0.6 31 4.6 0.2 3.2 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KND95964.1 - 0.19 11.0 0.0 0.4 9.9 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Lipase_3 PF01764.25 KND95965.1 - 3.5e-34 117.7 0.0 5.4e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 KND95965.1 - 0.00022 20.9 0.0 0.75 9.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 KND95965.1 - 0.042 14.4 0.0 0.065 13.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 KND95965.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Esterase PF00756.20 KND95965.1 - 0.14 11.7 0.0 1 9.0 0.0 2.0 1 1 1 2 2 2 0 Putative esterase Hydrolase_4 PF12146.8 KND95965.1 - 0.15 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 KND95965.1 - 0.17 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 KND95965.1 - 0.19 11.4 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0203 PF05254.12 KND95966.1 - 8.7e-27 93.2 2.7 1e-26 93.0 2.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.10 KND95966.1 - 0.00015 21.7 1.2 0.14 12.2 0.2 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.16 KND95966.1 - 0.0011 19.1 0.7 0.0015 18.6 0.7 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein COX17 PF05051.13 KND95966.1 - 0.017 15.5 0.8 0.039 14.3 0.8 1.6 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) EDS1_EP PF18117.1 KND95966.1 - 0.064 13.7 0.1 0.069 13.6 0.1 1.1 1 0 0 1 1 1 0 Enhanced disease susceptibility 1 protein EP domain DUF3128 PF11326.8 KND95966.1 - 0.082 13.3 2.4 0.5 10.8 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) Pet191_N PF10203.9 KND95966.1 - 0.17 12.2 1.6 2.7 8.3 0.1 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 DASH_Ask1 PF08655.10 KND95968.1 - 6.7e-23 80.4 1.1 1.7e-22 79.0 0.2 2.1 2 0 0 2 2 2 1 DASH complex subunit Ask1 HMG_box PF00505.19 KND95968.1 - 0.18 12.3 0.3 0.48 10.9 0.0 1.9 2 0 0 2 2 2 0 HMG (high mobility group) box MCM PF00493.23 KND95969.1 - 2.5e-97 324.4 0.6 4.3e-97 323.6 0.6 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KND95969.1 - 9.3e-31 106.3 0.0 1.7e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KND95969.1 - 1.5e-24 86.2 2.4 5.7e-24 84.4 2.1 2.2 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KND95969.1 - 2.6e-10 40.8 0.0 8.4e-10 39.2 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KND95969.1 - 2.3e-08 33.7 0.5 3.6e-07 29.8 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KND95969.1 - 0.0013 18.6 0.0 0.0032 17.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KND95969.1 - 0.0021 17.8 0.0 0.0073 16.0 0.0 1.9 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 KND95969.1 - 0.031 14.3 0.0 0.37 10.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KND95969.1 - 0.12 12.8 0.1 0.34 11.3 0.1 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 KND95969.1 - 0.15 11.9 0.2 9.8 5.9 0.0 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase Methyltransf_15 PF09445.10 KND95970.1 - 2.8e-47 160.3 0.1 3.6e-47 160.0 0.1 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KND95970.1 - 3.8e-11 43.5 0.0 6.6e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND95970.1 - 4e-10 39.7 0.0 5.5e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND95970.1 - 4.7e-08 33.6 0.0 8.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 KND95970.1 - 1.1e-06 28.5 0.0 2.4e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 KND95970.1 - 2.1e-05 24.0 0.0 2.9e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Ubie_methyltran PF01209.18 KND95970.1 - 3.5e-05 23.3 0.0 5.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KND95970.1 - 0.00016 21.0 1.6 0.00032 20.1 0.3 1.8 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltr_RsmB-F PF01189.17 KND95970.1 - 0.00016 21.3 0.0 0.00021 21.0 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Cons_hypoth95 PF03602.15 KND95970.1 - 0.0005 19.8 0.0 0.00074 19.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 KND95970.1 - 0.0015 18.1 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KND95970.1 - 0.0038 17.1 0.0 0.0071 16.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KND95970.1 - 0.0049 16.8 0.1 0.0075 16.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.16 KND95970.1 - 0.012 14.7 0.1 0.016 14.3 0.1 1.2 1 0 0 1 1 1 0 mRNA capping enzyme PrmA PF06325.13 KND95970.1 - 0.025 14.0 0.0 0.033 13.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 KND95970.1 - 0.032 15.0 0.0 0.071 13.9 0.0 1.5 2 0 0 2 2 1 0 Methyltransferase domain Met_10 PF02475.16 KND95970.1 - 0.035 13.8 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PCMT PF01135.19 KND95970.1 - 0.055 13.2 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MFS_1 PF07690.16 KND95971.1 - 9.2e-19 67.6 23.9 1.8e-18 66.6 23.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily V_ATPase_I PF01496.19 KND95971.1 - 0.0045 15.0 1.3 0.0066 14.4 1.3 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family MFS_1_like PF12832.7 KND95971.1 - 1.9 7.3 15.8 0.23 10.3 8.0 2.4 1 1 1 2 2 2 0 MFS_1 like family DEAD PF00270.29 KND95972.1 - 2.9e-38 131.4 0.1 5.6e-38 130.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND95972.1 - 2.4e-20 73.0 0.3 7.1e-20 71.4 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND95972.1 - 7.3e-10 39.1 0.0 2e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KND95972.1 - 0.016 14.7 1.0 0.044 13.3 0.0 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KND95972.1 - 0.033 14.5 0.4 0.17 12.2 0.4 2.2 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 KND95972.1 - 0.05 13.6 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain DUF2972 PF11186.8 KND95972.1 - 0.19 11.6 2.5 12 5.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2972) Raftlin PF15250.6 KND95972.1 - 1.8 7.3 10.7 2.7 6.6 10.7 1.2 1 0 0 1 1 1 0 Raftlin Ribosomal_S19 PF00203.21 KND95973.1 - 3e-24 84.7 0.0 3.7e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 PP2C PF00481.21 KND95974.1 - 3.6e-30 105.4 0.0 6.1e-26 91.6 0.0 3.3 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KND95974.1 - 0.00049 19.8 0.0 0.00097 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Ligase_CoA PF00549.19 KND95974.1 - 0.041 13.7 0.1 0.073 12.9 0.1 1.3 1 0 0 1 1 1 0 CoA-ligase Glutaredoxin PF00462.24 KND95975.1 - 1e-18 67.3 0.0 1.4e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 KND95975.1 - 0.0017 18.8 0.1 0.0021 18.5 0.1 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 KND95975.1 - 0.0037 17.6 0.0 0.0048 17.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 KND95975.1 - 0.0047 16.9 0.0 0.0077 16.2 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin domain Thioredoxin_4 PF13462.6 KND95975.1 - 0.0077 16.4 0.2 4.1 7.5 0.1 2.1 2 0 0 2 2 2 2 Thioredoxin DSBA PF01323.20 KND95975.1 - 0.034 13.9 0.3 2.4 7.9 0.1 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain TraF PF13728.6 KND95975.1 - 0.04 13.7 0.0 0.047 13.5 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Glyoxalase PF00903.25 KND95976.1 - 6.1e-35 120.2 0.0 1.7e-17 63.8 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KND95976.1 - 2.8e-13 50.1 0.0 1.4e-06 28.6 0.0 3.9 1 1 2 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 KND95976.1 - 1.8e-05 24.6 2.1 0.57 10.1 0.1 4.3 3 2 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KND95976.1 - 6.4e-05 23.7 0.0 0.11 13.3 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase-like domain CppA_N PF14506.6 KND95976.1 - 0.001 19.1 0.1 2.2 8.3 0.0 2.5 2 0 0 2 2 2 2 CppA N-terminal Glyoxalase_3 PF13468.6 KND95976.1 - 0.056 13.6 0.0 0.49 10.5 0.0 2.3 2 0 0 2 2 2 0 Glyoxalase-like domain Pantoate_transf PF02548.15 KND95977.1 - 1.3e-104 349.2 1.3 1.6e-104 348.9 1.3 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KND95977.1 - 4.3e-09 36.2 0.9 1.2e-08 34.8 0.2 1.9 2 1 0 2 2 2 1 Phosphoenolpyruvate phosphomutase KDGP_aldolase PF07071.11 KND95977.1 - 0.073 12.9 0.3 0.12 12.1 0.3 1.5 1 0 0 1 1 1 0 KDGP aldolase Fungal_trans PF04082.18 KND95979.1 - 1.1e-06 27.9 8.4 2.3e-06 26.9 8.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dus PF01207.17 KND95980.1 - 1.9e-73 247.3 0.0 2.5e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Abhydrolase_2 PF02230.16 KND95981.1 - 4.2e-56 190.2 0.1 4.8e-56 190.0 0.1 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 KND95981.1 - 5.7e-09 35.9 0.0 1.9e-08 34.2 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 KND95981.1 - 2.7e-07 30.1 0.0 0.0025 17.1 0.0 2.8 2 1 1 3 3 3 2 Serine aminopeptidase, S33 DLH PF01738.18 KND95981.1 - 8.9e-06 25.4 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KND95981.1 - 5.7e-05 22.9 0.4 0.0015 18.3 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KND95981.1 - 0.00017 22.2 0.0 0.00021 22.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 KND95981.1 - 0.0023 17.9 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 Cutinase Abhydrolase_3 PF07859.13 KND95981.1 - 0.0038 17.1 0.0 0.0054 16.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KND95981.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase AXE1 PF05448.12 KND95981.1 - 0.19 10.3 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Dopey_N PF04118.14 KND95982.1 - 4.1e-106 354.5 4.0 4.1e-106 354.5 4.0 2.7 3 0 0 3 3 3 1 Dopey, N-terminal UPF0172 PF03665.13 KND95983.1 - 0.14 12.2 0.3 0.27 11.3 0.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF327 PF03885.13 KND95983.1 - 0.33 10.9 3.5 0.34 10.9 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF327) RRM_1 PF00076.22 KND95984.1 - 1.3e-06 28.1 0.1 0.00016 21.4 0.1 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) bPH_5 PF10882.8 KND95984.1 - 0.035 14.2 0.1 0.091 12.8 0.1 1.6 1 0 0 1 1 1 0 Bacterial PH domain HSP9_HSP12 PF04119.12 KND95985.1 - 1.6e-25 89.3 6.5 1.7e-25 89.2 1.8 2.5 2 1 0 2 2 2 1 Heat shock protein 9/12 DUF3391 PF11871.8 KND95985.1 - 0.028 15.0 3.6 0.037 14.5 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) EspB PF05802.11 KND95985.1 - 0.16 12.0 8.2 0.33 10.9 8.3 1.5 1 1 0 1 1 1 0 Enterobacterial EspB protein YtxH PF12732.7 KND95985.1 - 3 8.4 13.0 4.1e+02 1.6 13.0 2.7 1 1 0 1 1 1 0 YtxH-like protein MT0933_antitox PF14013.6 KND95985.1 - 5.8 7.3 14.0 13 6.2 2.1 3.3 2 2 1 3 3 3 0 MT0933-like antitoxin protein AAA PF00004.29 KND95987.1 - 2.8e-92 306.0 0.0 1.1e-46 158.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KND95987.1 - 7.2e-23 80.1 0.1 4.4e-10 39.2 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KND95987.1 - 1.1e-14 54.5 0.0 1.4e-07 31.4 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KND95987.1 - 9.8e-13 48.6 0.0 8.8e-05 22.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KND95987.1 - 1.2e-11 45.3 2.2 0.0015 19.0 0.0 4.8 3 2 0 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 KND95987.1 - 5e-11 43.0 0.5 0.011 16.0 0.0 4.9 2 2 2 4 4 4 2 AAA domain AAA_33 PF13671.6 KND95987.1 - 9.8e-10 38.8 0.0 0.0021 18.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 KND95987.1 - 2.4e-09 37.3 0.3 0.0017 18.4 0.1 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KND95987.1 - 4.9e-09 36.8 0.1 7.5e-05 23.3 0.0 3.6 3 2 1 4 4 2 2 AAA domain TIP49 PF06068.13 KND95987.1 - 6.4e-09 35.5 0.0 0.0002 20.7 0.0 2.7 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 KND95987.1 - 2.3e-08 34.1 0.0 0.0019 18.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KND95987.1 - 3.7e-08 33.8 0.0 0.00069 19.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KND95987.1 - 9e-08 32.5 0.1 0.0081 16.5 0.0 3.2 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.21 KND95987.1 - 2.8e-07 30.1 0.3 0.02 14.3 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KND95987.1 - 3.8e-07 30.2 0.0 0.0014 18.6 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain IstB_IS21 PF01695.17 KND95987.1 - 4.3e-07 29.8 0.1 0.052 13.3 0.0 3.0 2 1 1 3 3 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.12 KND95987.1 - 5.1e-07 29.2 0.0 0.037 13.3 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin ABC_tran PF00005.27 KND95987.1 - 6.3e-07 30.0 0.4 0.055 14.0 0.0 3.4 3 1 0 3 3 3 2 ABC transporter Cytidylate_kin2 PF13189.6 KND95987.1 - 9.3e-07 29.1 0.0 0.00021 21.5 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_17 PF13207.6 KND95987.1 - 2.4e-06 28.0 3.3 0.00093 19.6 0.0 3.4 4 0 0 4 4 2 1 AAA domain Vps4_C PF09336.10 KND95987.1 - 3.1e-06 27.1 0.1 0.058 13.4 0.0 2.6 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain AAA_3 PF07726.11 KND95987.1 - 8.3e-06 25.7 0.0 0.054 13.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KND95987.1 - 9.2e-06 25.4 1.5 0.22 11.1 0.1 4.3 3 1 1 4 4 4 1 AAA domain AAA_7 PF12775.7 KND95987.1 - 1.8e-05 24.3 0.0 0.03 13.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 KND95987.1 - 3.1e-05 23.8 0.0 0.061 13.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain SKI PF01202.22 KND95987.1 - 3.5e-05 24.0 0.0 0.043 13.9 0.0 2.8 2 0 0 2 2 2 1 Shikimate kinase TsaE PF02367.17 KND95987.1 - 4.3e-05 23.5 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KND95987.1 - 4.7e-05 22.7 0.0 1.5 7.9 0.0 3.7 3 0 0 3 3 3 2 NB-ARC domain NACHT PF05729.12 KND95987.1 - 0.00018 21.4 0.1 0.68 9.8 0.0 3.0 3 0 0 3 3 2 2 NACHT domain ATPase PF06745.13 KND95987.1 - 0.00044 19.7 2.5 1.9 7.7 0.0 3.8 5 0 0 5 5 3 2 KaiC Sigma54_activat PF00158.26 KND95987.1 - 0.00053 19.7 0.0 0.24 11.1 0.0 2.7 3 0 0 3 3 2 1 Sigma-54 interaction domain ATPase_2 PF01637.18 KND95987.1 - 0.00086 19.3 2.3 1.3 8.9 0.0 3.5 3 2 0 3 3 2 2 ATPase domain predominantly from Archaea DUF815 PF05673.13 KND95987.1 - 0.0011 18.2 0.0 0.15 11.2 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 KND95987.1 - 0.0011 18.1 0.1 0.83 8.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Viral_helicase1 PF01443.18 KND95987.1 - 0.0014 18.4 0.0 0.63 9.7 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 KND95987.1 - 0.0021 18.0 0.4 0.87 9.5 0.0 2.9 3 0 0 3 3 2 1 NTPase AAA_11 PF13086.6 KND95987.1 - 0.0029 17.4 5.3 1.2 8.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain TniB PF05621.11 KND95987.1 - 0.0049 16.3 0.0 4.7 6.6 0.0 3.5 3 0 0 3 3 3 0 Bacterial TniB protein PduV-EutP PF10662.9 KND95987.1 - 0.0063 16.3 0.0 1.8 8.3 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Sigma54_activ_2 PF14532.6 KND95987.1 - 0.0065 16.6 0.1 6.8 6.8 0.0 3.0 3 0 0 3 3 2 0 Sigma-54 interaction domain Cytidylate_kin PF02224.18 KND95987.1 - 0.0089 15.8 0.1 0.63 9.7 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase PhoH PF02562.16 KND95987.1 - 0.011 15.2 0.2 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Bac_DnaA PF00308.18 KND95987.1 - 0.017 14.9 0.1 3.9 7.2 0.0 3.9 3 2 0 3 3 3 0 Bacterial dnaA protein IPT PF01745.16 KND95987.1 - 0.022 14.2 0.0 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase CorA PF01544.18 KND95987.1 - 0.046 13.0 0.4 0.096 12.0 0.0 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein MMR_HSR1 PF01926.23 KND95987.1 - 0.049 13.7 0.2 1.1 9.4 0.0 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 KND95987.1 - 0.055 13.2 0.0 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain FeoB_N PF02421.18 KND95987.1 - 0.072 12.6 0.2 1.5 8.3 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B ADK PF00406.22 KND95987.1 - 0.079 13.1 2.6 2.2 8.4 0.1 3.0 3 0 0 3 3 3 0 Adenylate kinase CPT PF07931.12 KND95987.1 - 0.084 12.7 0.0 0.86 9.4 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.6 KND95987.1 - 0.088 13.1 2.5 4.7 7.5 0.1 3.1 3 1 0 3 3 2 0 AAA domain PAS_10 PF13596.6 KND95987.1 - 0.089 13.4 0.1 10 6.8 0.0 3.0 2 1 1 3 3 2 0 PAS domain YfbU PF03887.14 KND95987.1 - 0.13 12.3 1.6 0.62 10.1 0.8 2.2 2 0 0 2 2 2 0 YfbU domain AAA_30 PF13604.6 KND95987.1 - 0.14 11.9 0.2 15 5.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KND95987.1 - 0.21 12.1 0.0 0.21 12.1 0.0 3.6 4 0 0 4 4 2 0 AAA domain Hydin_ADK PF17213.3 KND95987.1 - 0.39 11.0 3.4 28 4.9 0.0 3.1 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Abhydrolase_1 PF00561.20 KND95988.1 - 1.3e-24 87.2 0.0 1.5e-23 83.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KND95988.1 - 7.3e-17 62.7 0.0 9.1e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND95988.1 - 6.6e-11 41.9 0.0 9e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KND95988.1 - 0.00098 18.9 0.0 1.4 8.6 0.0 2.2 1 1 1 2 2 2 2 PGAP1-like protein Esterase PF00756.20 KND95988.1 - 0.059 13.0 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase CN_hydrolase PF00795.22 KND95990.1 - 3.3e-55 187.2 0.0 3.7e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase SBBP PF06739.11 KND95990.1 - 0.049 13.6 4.4 3.4 7.7 0.1 2.9 2 1 0 2 2 2 0 Beta-propeller repeat MFS_1 PF07690.16 KND95993.1 - 2.3e-37 128.7 84.3 1.6e-34 119.4 53.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0182 PF03699.13 KND95993.1 - 0.2 9.7 2.1 0.28 9.3 2.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Mannosyl_trans3 PF11051.8 KND95995.1 - 1.1e-78 264.5 0.1 1.5e-78 264.0 0.1 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Shikimate_dh_N PF08501.11 KND95996.1 - 8.8e-19 67.6 0.0 6e-18 64.9 0.0 2.4 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain YoaP PF14268.6 KND95996.1 - 0.018 14.5 0.0 8.9 5.9 0.1 2.4 2 0 0 2 2 2 0 YoaP-like SDH_C PF18317.1 KND95996.1 - 0.032 14.0 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate 5'-dehydrogenase C-terminal domain DSPc PF00782.20 KND95996.1 - 0.085 12.7 0.0 0.15 11.9 0.0 1.5 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain FAM219A PF15260.6 KND95996.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein family FAM219A UPF0061 PF02696.14 KND95997.1 - 2.6e-127 425.4 0.5 3.6e-127 425.0 0.5 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family CdhD PF03599.16 KND95997.1 - 0.21 10.3 0.3 0.46 9.1 0.1 1.6 2 0 0 2 2 2 0 CO dehydrogenase/acetyl-CoA synthase delta subunit SH3_9 PF14604.6 KND96000.1 - 2.4e-09 36.9 0.1 1.2e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KND96000.1 - 1.2e-07 31.2 0.1 2.1e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KND96000.1 - 4.5e-07 29.5 0.0 8.6e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain CDO_I PF05995.12 KND96000.1 - 0.039 13.3 0.1 0.066 12.5 0.1 1.3 1 0 0 1 1 1 0 Cysteine dioxygenase type I Curto_V3 PF07436.11 KND96001.1 - 0.082 13.3 0.1 0.09 13.2 0.1 1.1 1 0 0 1 1 1 0 Curtovirus V3 protein AOX PF01786.17 KND96004.1 - 8e-93 309.9 0.6 9.7e-93 309.7 0.6 1.1 1 0 0 1 1 1 1 Alternative oxidase Aa_trans PF01490.18 KND96005.1 - 1.4e-92 310.5 23.0 1.7e-92 310.3 23.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UPF0060 PF02694.15 KND96005.1 - 0.17 12.2 0.1 0.17 12.2 0.1 3.0 4 0 0 4 4 4 0 Uncharacterised BCR, YnfA/UPF0060 family DUF3377 PF11857.8 KND96006.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Peptidase_M24 PF00557.24 KND96009.1 - 5.5e-44 150.4 0.2 6.8e-44 150.1 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF4710 PF15828.5 KND96009.1 - 1.3 9.2 6.5 14 5.9 5.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) ALG11_N PF15924.5 KND96012.1 - 4.1e-72 242.6 0.2 5.8e-72 242.1 0.2 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KND96012.1 - 5.9e-14 52.0 0.0 1.1e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KND96012.1 - 2.8e-05 24.6 0.0 5.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Coatomer_WDAD PF04053.14 KND96013.1 - 9.4e-166 552.3 2.8 1.5e-165 551.6 2.8 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 KND96013.1 - 2.8e-37 126.1 1.9 1.6e-06 28.7 0.0 9.3 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND96013.1 - 8.4e-08 32.4 0.2 5.5 7.4 0.0 6.3 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KND96013.1 - 0.00054 18.7 5.0 0.014 14.1 0.1 3.6 1 1 4 5 5 5 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KND96013.1 - 0.0016 18.5 0.1 1.6 8.8 0.0 4.4 2 2 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region MetallophosC PF16370.5 KND96013.1 - 0.0048 17.1 0.9 0.037 14.3 0.2 2.6 1 1 1 2 2 2 1 C terminal of Calcineurin-like phosphoesterase PQQ PF01011.21 KND96013.1 - 3.1 7.9 5.9 1.7 8.7 0.0 3.8 5 0 0 5 5 5 0 PQQ enzyme repeat FtsJ PF01728.19 KND96014.1 - 3.6e-21 76.0 0.0 5.5e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 KND96014.1 - 0.0041 17.0 0.0 0.0071 16.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Fungal_trans PF04082.18 KND96015.1 - 3e-16 59.3 2.3 5.8e-16 58.3 2.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND96015.1 - 6e-05 23.1 14.0 0.00014 21.9 14.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.22 KND96017.1 - 0.00022 21.0 0.0 0.072 12.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.27 KND96018.1 - 4.6e-30 103.4 7.3 2.7e-13 49.6 0.0 3.4 2 1 0 3 3 3 3 Mitochondrial carrier protein TPT PF03151.16 KND96019.1 - 2.9e-20 72.8 5.0 6.2e-20 71.7 5.0 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KND96019.1 - 0.02 15.1 16.4 0.14 12.3 16.3 1.9 1 1 0 1 1 1 0 EamA-like transporter family DUF2518 PF10726.9 KND96019.1 - 5.6 6.6 6.8 0.57 9.8 1.7 2.0 2 1 0 2 2 2 0 Protein of function (DUF2518) Cucumo_2B PF03263.13 KND96022.1 - 0.019 15.4 2.8 0.084 13.3 0.0 2.0 2 0 0 2 2 2 0 Cucumovirus protein 2B Na_H_Exchanger PF00999.21 KND96023.1 - 5.4e-69 232.8 38.7 6.9e-69 232.5 38.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CPP1-like PF11833.8 KND96023.1 - 0.66 9.6 2.9 1.5 8.5 0.2 2.7 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Wzy_C PF04932.15 KND96023.1 - 0.85 9.2 0.0 0.85 9.2 0.0 3.7 3 2 0 3 3 3 0 O-Antigen ligase Ndc1_Nup PF09531.10 KND96024.1 - 7e-116 388.3 13.9 7.9e-116 388.2 13.9 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup PSD1 PF07587.11 KND96025.1 - 0.11 12.0 2.0 0.58 9.6 2.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1553) LMBR1 PF04791.16 KND96025.1 - 5.6 5.7 5.4 7 5.4 5.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ERCC4 PF02732.15 KND96026.1 - 7.2e-20 71.8 0.9 1.7e-19 70.5 0.9 1.7 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 KND96026.1 - 0.032 14.6 0.0 0.083 13.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF3470 PF11953.8 KND96027.1 - 0.15 12.1 2.6 15 5.7 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF3470) PRP3 PF08572.10 KND96028.1 - 2.4e-61 207.3 11.5 3.6e-61 206.8 11.5 1.2 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KND96028.1 - 1.9e-39 135.1 0.2 1.9e-39 135.1 0.2 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1115) ADH_N PF08240.12 KND96030.1 - 1.1e-25 89.6 1.6 2.5e-25 88.5 1.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KND96030.1 - 4.5e-17 62.2 0.0 7.5e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KND96030.1 - 1.9e-12 48.4 0.0 4.5e-12 47.2 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KND96030.1 - 1e-05 25.1 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KND96030.1 - 0.0002 20.8 0.4 0.00058 19.2 0.0 1.7 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 KND96030.1 - 0.01 15.2 0.1 0.02 14.2 0.1 1.4 1 0 0 1 1 1 0 ThiF family NAD_binding_7 PF13241.6 KND96030.1 - 0.018 15.5 0.0 0.036 14.5 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KND96030.1 - 0.028 13.7 0.1 0.041 13.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain SIS_2 PF13580.6 KND96030.1 - 0.048 13.7 0.1 12 5.9 0.0 2.4 2 0 0 2 2 2 0 SIS domain 2-Hacid_dh_C PF02826.19 KND96030.1 - 0.058 12.7 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KND96030.1 - 0.075 13.3 0.1 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Ribonuc_red_lgC PF02867.15 KND96031.1 - 4.6e-187 622.7 0.0 5.5e-187 622.5 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KND96031.1 - 4.7e-11 42.5 0.0 1.2e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain 5_3_exonuc PF01367.20 KND96031.1 - 0.15 12.6 0.0 0.45 11.1 0.0 1.7 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold OPT PF03169.15 KND96033.1 - 2.4e-188 627.7 54.2 2.7e-188 627.5 54.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4231 PF14015.6 KND96033.1 - 8.1 7.0 7.1 2.3 8.7 0.2 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) LCCL PF03815.19 KND96035.1 - 7e-05 22.9 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 LCCL domain Coatomer_E PF04733.14 KND96036.1 - 2.1e-16 60.2 3.6 1.9e-14 53.8 0.9 2.2 2 0 0 2 2 2 2 Coatomer epsilon subunit Septin PF00735.18 KND96037.1 - 7.8e-78 261.6 0.8 7.8e-78 261.6 0.8 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KND96037.1 - 5.3e-07 29.7 0.0 1.3e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KND96037.1 - 0.0022 17.9 2.4 0.004 17.1 0.0 2.4 3 0 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 KND96037.1 - 0.0026 18.3 0.1 0.0079 16.7 0.0 1.9 2 0 0 2 2 2 1 ABC transporter Roc PF08477.13 KND96037.1 - 0.003 17.8 0.0 0.006 16.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KND96037.1 - 0.004 16.5 0.5 0.0095 15.3 0.0 1.9 2 0 0 2 2 2 1 AIG1 family AAA_29 PF13555.6 KND96037.1 - 0.0072 16.1 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KND96037.1 - 0.0073 15.9 0.1 1.4 8.4 0.0 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF676 PF05057.14 KND96039.1 - 1.8e-30 106.1 0.0 2.9e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 KND96039.1 - 2.9e-05 24.0 0.0 6.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Palm_thioest PF02089.15 KND96039.1 - 0.0077 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Ysc84 PF04366.12 KND96040.1 - 1.6e-29 102.2 0.1 2.4e-29 101.7 0.1 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KND96040.1 - 1.1e-16 60.1 0.1 1.9e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KND96040.1 - 3.6e-12 45.9 0.0 8.8e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KND96040.1 - 1.5e-11 43.8 0.0 3.4e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Arm PF00514.23 KND96041.1 - 1.8e-63 208.8 33.9 2.7e-10 39.9 0.1 11.5 11 1 1 12 12 12 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KND96041.1 - 1.4e-14 54.2 18.3 0.001 19.5 0.2 7.6 7 2 2 9 9 8 5 HEAT-like repeat HEAT_2 PF13646.6 KND96041.1 - 3.4e-11 43.4 12.4 0.029 14.8 0.3 6.6 4 1 3 8 8 7 4 HEAT repeats KAP PF05804.12 KND96041.1 - 1.2e-10 40.3 7.5 7e-07 27.8 1.5 2.4 1 1 2 3 3 3 2 Kinesin-associated protein (KAP) Adaptin_N PF01602.20 KND96041.1 - 7.5e-10 38.0 7.4 1.6e-05 23.7 2.4 2.5 1 1 1 2 2 2 2 Adaptin N terminal region HEAT PF02985.22 KND96041.1 - 5.2e-08 32.5 16.4 0.24 11.8 0.1 8.4 8 0 0 8 8 8 3 HEAT repeat Arm_2 PF04826.13 KND96041.1 - 1.9e-05 24.2 12.6 0.00013 21.5 2.9 3.0 2 1 0 3 3 3 2 Armadillo-like Vac14_Fab1_bd PF12755.7 KND96041.1 - 0.00024 21.6 0.1 0.96 10.1 0.0 3.0 2 1 0 2 2 2 2 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.8 KND96041.1 - 0.0035 17.4 6.4 1.2 9.3 0.1 4.9 4 2 2 7 7 7 1 V-ATPase subunit H DUF3361 PF11841.8 KND96041.1 - 0.0088 16.0 7.5 0.32 10.9 0.1 4.6 2 1 2 6 6 6 1 Domain of unknown function (DUF3361) DUF5578 PF17741.1 KND96041.1 - 0.011 15.2 3.8 3.6 6.9 0.1 4.3 2 2 4 6 6 6 0 Family of unknown function (DUF5578) Tti2 PF10521.9 KND96041.1 - 0.035 13.7 0.3 1 8.9 0.0 2.9 3 0 0 3 3 3 0 Tti2 family Snf7 PF03357.21 KND96042.1 - 1.4e-16 60.6 16.8 3e-16 59.5 16.8 1.6 1 1 0 1 1 1 1 Snf7 RBFA PF02033.18 KND96042.1 - 0.0038 17.7 5.5 1.1 9.8 2.5 3.3 3 0 0 3 3 3 2 Ribosome-binding factor A PspB PF06667.12 KND96042.1 - 0.0094 16.0 0.1 0.037 14.1 0.1 2.1 1 0 0 1 1 1 1 Phage shock protein B Arg_repressor PF01316.21 KND96042.1 - 0.045 13.5 1.5 0.18 11.6 0.0 2.7 2 1 0 2 2 2 0 Arginine repressor, DNA binding domain Fe_dep_repr_C PF02742.15 KND96042.1 - 0.51 10.5 3.7 15 5.7 0.9 2.6 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain DUF150 PF02576.17 KND96042.1 - 1.9 8.9 4.8 1.5 9.3 0.2 2.9 3 0 0 3 3 3 0 RimP N-terminal domain ParA PF10609.9 KND96043.1 - 3.5e-91 305.0 0.0 4.1e-91 304.8 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KND96043.1 - 5.7e-11 42.6 0.0 1.2e-10 41.5 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KND96043.1 - 2.6e-06 27.5 0.0 1.7e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 KND96043.1 - 7.2e-06 25.5 0.0 1.8e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 KND96043.1 - 8.2e-05 21.9 0.2 0.00077 18.7 0.0 2.1 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.6 KND96043.1 - 0.0011 18.9 0.0 0.13 12.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KND96043.1 - 0.019 14.6 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KND96043.1 - 0.019 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase CBP_BcsQ PF06564.12 KND96043.1 - 0.089 12.3 0.2 0.44 10.0 0.2 1.9 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ NB-ARC PF00931.22 KND96043.1 - 0.15 11.2 0.1 0.23 10.6 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain Zn_Tnp_IS1595 PF12760.7 KND96043.1 - 0.15 12.0 0.4 0.54 10.3 0.2 2.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DnaB_C PF03796.15 KND96043.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain zf_Rg PF17915.1 KND96043.1 - 0.81 9.1 7.3 0.45 10.0 0.1 2.4 2 0 0 2 2 2 0 Reverse gyrase zinc finger Nucleoporin2 PF04096.14 KND96044.1 - 3.8e-37 127.7 0.2 1.9e-36 125.4 0.0 2.3 2 0 0 2 2 2 1 Nucleoporin autopeptidase Nup96 PF12110.8 KND96044.1 - 4.2e-23 81.9 0.2 2.3e-10 40.1 0.0 2.4 1 1 0 2 2 2 2 Nuclear protein 96 Nucleoporin_FG PF13634.6 KND96044.1 - 3.6e-19 69.4 118.2 2.3e-09 38.0 32.3 4.2 1 1 5 6 6 6 5 Nucleoporin FG repeat region DUF3323 PF11796.8 KND96044.1 - 0.056 13.3 0.1 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) YjeF_N PF03853.15 KND96045.1 - 5.7e-29 101.2 0.0 8.9e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 KND96045.1 - 4.9e-08 33.8 4.8 4.9e-08 33.8 4.8 2.3 2 0 0 2 2 2 1 FDF domain LSM PF01423.22 KND96045.1 - 0.054 13.2 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 LSM domain Kinesin PF00225.23 KND96046.1 - 5.5e-96 321.4 1.6 6.2e-96 321.2 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KND96046.1 - 1.3e-25 90.1 0.6 3.3e-25 88.8 0.0 2.0 2 1 0 2 2 2 1 Microtubule binding YabA PF06156.13 KND96046.1 - 0.098 13.3 9.5 2.4 8.8 4.7 3.0 3 0 0 3 3 3 0 Initiation control protein YabA Exonuc_VII_L PF02601.15 KND96046.1 - 1.1 8.8 5.9 1.6 8.2 5.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2530 PF10745.9 KND96047.1 - 0.018 15.2 6.8 1.6 9.1 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Titin_Ig-rpts PF06582.12 KND96050.1 - 0.13 12.2 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 Titin repeat Ac76 PF05814.11 KND96050.1 - 1.4 9.0 5.4 11 6.1 0.2 2.8 2 0 0 2 2 2 0 Orf76 (Ac76) UBX PF00789.20 KND96051.1 - 5.9e-11 42.4 0.0 1.5e-10 41.1 0.0 1.7 2 0 0 2 2 2 1 UBX domain PALP PF00291.25 KND96053.1 - 1.8e-67 227.9 0.0 2.3e-67 227.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KND96053.1 - 2.2e-12 47.2 0.0 3e-08 34.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain E3_binding PF02817.17 KND96053.1 - 1.4 9.3 3.4 15 6.1 0.1 3.2 3 0 0 3 3 3 0 e3 binding domain TFIIS_M PF07500.14 KND96054.1 - 1.3e-29 103.0 3.4 1.3e-29 103.0 3.4 1.9 2 1 1 3 3 3 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KND96054.1 - 4.8e-18 64.7 7.5 7.5e-18 64.1 7.5 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KND96054.1 - 5.2e-11 42.4 1.2 1.6e-10 40.9 0.9 2.1 1 1 0 1 1 1 1 TFIIS helical bundle-like domain Elf1 PF05129.13 KND96054.1 - 0.099 12.7 2.5 0.24 11.5 2.5 1.7 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Baculo_LEF5_C PF11792.8 KND96054.1 - 0.1 12.3 1.7 0.17 11.6 1.7 1.3 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain CSTF2_hinge PF14327.6 KND96055.1 - 2.2e-17 63.2 4.0 3.5e-17 62.6 4.0 1.3 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KND96055.1 - 2.4e-16 59.3 0.0 5e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KND96055.1 - 0.02 14.7 0.0 0.052 13.4 0.0 1.7 1 0 0 1 1 1 0 Occluded RNA-recognition motif BID PF06393.11 KND96055.1 - 0.023 14.2 0.4 0.042 13.4 0.4 1.3 1 0 0 1 1 1 0 BH3 interacting domain (BID) TINF2_N PF14973.6 KND96055.1 - 0.045 14.1 1.0 0.07 13.5 1.0 1.3 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus FluMu_N PF17891.1 KND96055.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain Comm PF15957.5 KND96056.1 - 0.14 12.5 2.1 0.76 10.1 0.0 2.2 2 0 0 2 2 2 0 Commissureless Aldo_ket_red PF00248.21 KND96060.1 - 4.5e-26 91.7 0.0 6.4e-24 84.7 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family Gp58 PF07902.11 KND96060.1 - 0.15 10.3 0.0 0.2 9.9 0.0 1.1 1 0 0 1 1 1 0 gp58-like protein MFS_1 PF07690.16 KND96061.1 - 1.5e-18 66.9 43.3 1.1e-12 47.5 16.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KND96061.1 - 0.00034 19.3 9.7 0.00034 19.3 9.7 3.2 1 1 2 3 3 3 1 MFS/sugar transport protein PEN-2 PF10251.9 KND96061.1 - 3.2 8.2 6.4 2.6 8.5 0.3 3.6 3 0 0 3 3 3 0 Presenilin enhancer-2 subunit of gamma secretase Paf1 PF03985.13 KND96062.1 - 1.1e-88 298.2 22.1 1.2e-88 298.0 22.1 1.0 1 0 0 1 1 1 1 Paf1 DUF1824 PF08854.10 KND96062.1 - 0.048 13.6 0.6 0.14 12.1 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) MINDY_DUB PF04424.13 KND96063.1 - 3.9e-13 49.5 0.3 1.4e-12 47.6 0.3 1.9 1 1 0 1 1 1 1 MINDY deubiquitinase SQS_PSY PF00494.19 KND96064.1 - 3.6e-42 144.7 0.0 4.5e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF1870 PF08965.10 KND96064.1 - 0.018 15.0 0.0 5.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1870) Gtr1_RagA PF04670.12 KND96066.1 - 9.7e-82 273.8 4.1 1.2e-81 273.5 4.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KND96066.1 - 1.7e-05 24.3 0.2 3.9e-05 23.2 0.2 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KND96066.1 - 0.0001 21.9 0.2 0.00019 21.1 0.2 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND96066.1 - 0.001 19.3 0.1 0.0024 18.1 0.1 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ICMT PF04140.14 KND96067.1 - 5.3e-22 78.1 0.3 5.3e-22 78.1 0.3 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KND96067.1 - 2.6e-12 47.1 1.9 2.6e-12 47.1 1.9 2.2 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 KND96067.1 - 1.8e-06 27.7 1.6 2.9e-06 27.0 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF3836 PF12930.7 KND96067.1 - 0.76 9.5 3.6 1.2 8.9 0.1 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF3836) FA_desaturase PF00487.24 KND96068.1 - 4.4e-25 89.0 31.9 6.4e-25 88.4 31.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Endonuclea_NS_2 PF13930.6 KND96068.1 - 0.11 12.6 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease DnaJ PF00226.31 KND96070.1 - 1.3e-21 76.5 1.9 1.8e-21 76.1 0.1 2.3 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 KND96070.1 - 7.1e-14 51.7 8.6 5.4e-12 45.7 2.8 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KND96070.1 - 1.8e-10 40.9 6.8 1.3e-08 35.0 1.2 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KND96070.1 - 3.8e-06 27.2 10.5 0.0021 18.4 0.2 3.5 4 0 0 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KND96070.1 - 2.2e-05 24.7 4.7 0.098 13.2 0.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND96070.1 - 3.3e-05 24.3 5.5 0.13 13.2 0.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KND96070.1 - 0.026 14.9 1.6 0.24 11.9 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 KND96070.1 - 0.64 10.1 11.3 0.092 12.8 0.5 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger FPN1 PF06963.12 KND96070.1 - 0.76 8.3 2.4 0.58 8.6 0.7 1.6 2 0 0 2 2 2 0 Ferroportin1 (FPN1) Evr1_Alr PF04777.13 KND96070.1 - 1.2 9.6 4.8 0.44 11.0 0.6 2.4 2 0 0 2 2 2 0 Erv1 / Alr family DUF948 PF06103.11 KND96072.1 - 0.81 10.0 2.2 2.1 8.7 0.8 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF883 PF05957.13 KND96072.1 - 0.9 10.2 26.9 0.27 11.8 1.1 5.1 2 1 5 7 7 7 0 Bacterial protein of unknown function (DUF883) ING PF12998.7 KND96072.1 - 4.1 8.0 21.8 5.6 7.6 1.2 4.4 2 1 2 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding tRNA-synt_2b PF00587.25 KND96073.1 - 5.4e-36 124.2 0.0 7.9e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KND96073.1 - 0.05 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Anticodon binding domain Ribosomal_L31 PF01197.18 KND96073.1 - 0.11 12.8 0.3 0.28 11.4 0.3 1.7 1 0 0 1 1 1 0 Ribosomal protein L31 Sec61_beta PF03911.16 KND96075.1 - 1.9e-16 59.8 1.7 2.2e-16 59.6 1.6 1.1 1 0 0 1 1 1 1 Sec61beta family Podoplanin PF05808.11 KND96075.1 - 0.1 12.7 0.1 0.11 12.6 0.1 1.1 1 0 0 1 1 1 0 Podoplanin RRM_1 PF00076.22 KND96078.1 - 1.5e-06 27.9 0.1 3.9e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PP2C PF00481.21 KND96079.1 - 9.2e-75 251.6 0.0 1.9e-74 250.6 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C Dpoe2NT PF12213.8 KND96079.1 - 0.1 12.9 1.3 0.15 12.4 0.0 1.8 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal DUF2017 PF09438.10 KND96079.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) MOZ_SAS PF01853.18 KND96081.1 - 4.2e-71 238.3 0.3 6.7e-71 237.7 0.3 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KND96081.1 - 1.8e-20 72.3 3.9 3.7e-20 71.3 3.9 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 KND96081.1 - 0.082 13.3 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain KIX PF02172.16 KND96081.1 - 0.12 12.6 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 KIX domain TatD_DNase PF01026.21 KND96082.1 - 1.8e-41 142.3 0.0 5.9e-41 140.5 0.0 1.8 1 1 0 1 1 1 1 TatD related DNase DUF5610 PF18433.1 KND96082.1 - 0.073 13.6 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5610) DnaJ PF00226.31 KND96083.1 - 7.3e-09 35.6 0.2 7.3e-09 35.6 0.2 2.4 3 1 0 3 3 3 1 DnaJ domain ATP-synt_ab PF00006.25 KND96084.1 - 8.7e-63 211.8 0.0 1.2e-62 211.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATPase PF06745.13 KND96084.1 - 0.0061 15.9 1.2 0.0069 15.8 0.3 1.6 2 0 0 2 2 2 1 KaiC NB-ARC PF00931.22 KND96084.1 - 0.0085 15.3 0.4 0.059 12.6 0.1 2.0 2 0 0 2 2 2 1 NB-ARC domain RsgA_GTPase PF03193.16 KND96084.1 - 0.034 14.1 0.1 0.067 13.1 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 KND96084.1 - 0.039 13.9 0.2 0.094 12.6 0.1 1.7 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 KND96084.1 - 0.061 13.7 0.8 0.38 11.1 0.2 2.1 2 0 0 2 2 2 0 AAA domain DUF463 PF04317.12 KND96084.1 - 0.076 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 T3SS_ATPase_C PF18269.1 KND96084.1 - 0.083 12.8 0.2 0.51 10.2 0.2 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain AAA_16 PF13191.6 KND96084.1 - 0.083 13.3 0.2 0.28 11.6 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 KND96084.1 - 0.09 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 KND96084.1 - 0.18 11.8 0.1 0.41 10.7 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP-synt_ab_N PF02874.23 KND96084.1 - 0.18 12.3 2.2 0.28 11.7 0.6 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, beta-barrel domain Pox_A32 PF04665.12 KND96084.1 - 0.23 10.9 0.1 0.39 10.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein JmjC PF02373.22 KND96086.1 - 1.2e-39 135.3 0.2 2.8e-39 134.1 0.2 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 KND96086.1 - 9.7e-12 44.6 5.2 9.7e-12 44.6 5.2 2.5 2 0 0 2 2 2 1 PHD-finger JmjN PF02375.17 KND96086.1 - 9.1e-10 38.3 0.0 2e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 jmjN domain PHD_2 PF13831.6 KND96086.1 - 0.0053 16.3 1.0 0.0053 16.3 1.0 3.1 3 0 0 3 3 2 1 PHD-finger IGR PF09597.10 KND96086.1 - 0.032 14.3 0.0 1.4 9.1 0.0 3.2 3 0 0 3 3 3 0 IGR protein motif ASD2 PF08687.11 KND96086.1 - 0.13 11.8 4.6 0.22 11.1 4.6 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 zf-HC5HC2H PF13771.6 KND96086.1 - 0.13 12.5 0.1 0.13 12.5 0.1 2.3 2 0 0 2 2 2 0 PHD-like zinc-binding domain C1_2 PF03107.16 KND96086.1 - 0.17 12.2 8.2 0.77 10.1 2.3 2.9 2 0 0 2 2 2 0 C1 domain Prok-RING_1 PF14446.6 KND96086.1 - 0.24 11.3 9.6 0.16 11.9 2.2 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Use1 PF09753.9 KND96086.1 - 1.2 8.8 7.1 2 8.0 7.1 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 BRF1 PF07741.13 KND96086.1 - 2 8.8 5.9 4.6 7.7 5.9 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain P5CR_dimer PF14748.6 KND96087.1 - 1.5e-33 115.1 4.6 3.4e-33 114.0 4.6 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KND96087.1 - 6.5e-09 36.3 0.3 1.7e-08 34.9 0.1 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KND96087.1 - 0.00049 20.1 0.1 0.00069 19.6 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KND96087.1 - 0.0017 18.0 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Fer4_14 PF13394.6 KND96087.1 - 0.016 15.3 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain RcsD_ABL PF16359.5 KND96087.1 - 0.13 12.4 0.0 0.75 10.0 0.0 2.0 2 0 0 2 2 2 0 RcsD-ABL domain STI1 PF17830.1 KND96089.1 - 0.0043 17.0 0.1 0.01 15.8 0.1 1.7 1 1 0 1 1 1 1 STI1 domain Ribonuc_red_lgN PF00317.21 KND96089.1 - 0.021 14.8 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain DUF5365 PF17326.2 KND96089.1 - 0.041 14.3 0.1 0.056 13.9 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5365) ComZ PF10815.8 KND96089.1 - 0.094 12.7 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 ComZ Com_YlbF PF06133.11 KND96089.1 - 0.11 13.1 0.1 1.5 9.5 0.0 2.0 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Helicase_C PF00271.31 KND96091.1 - 3.2e-25 88.6 0.2 1.3e-24 86.6 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KND96091.1 - 2.8e-18 66.3 0.0 7.9e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase CMS1 PF14617.6 KND96091.1 - 0.051 12.9 0.2 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit T5orf172 PF10544.9 KND96092.1 - 9.8e-07 29.3 2.8 0.0018 18.8 0.2 3.1 1 1 1 2 2 2 2 T5orf172 domain MUG113 PF13455.6 KND96092.1 - 1.2e-06 29.0 5.6 3.1e-05 24.5 3.0 3.1 2 1 0 2 2 2 1 Meiotically up-regulated gene 113 zf-primase PF09329.11 KND96092.1 - 0.3 10.9 3.1 0.58 10.0 3.1 1.5 1 0 0 1 1 1 0 Primase zinc finger Cys_Met_Meta_PP PF01053.20 KND96093.1 - 5.1e-145 482.8 0.0 5.9e-145 482.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KND96093.1 - 6.6e-10 38.5 0.2 1.3e-09 37.6 0.2 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KND96093.1 - 1.6e-08 34.2 0.0 2.9e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KND96093.1 - 7.4e-07 28.8 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 KND96093.1 - 4.3e-05 22.2 0.2 6.5e-05 21.6 0.2 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 KND96093.1 - 0.002 17.1 0.0 0.0029 16.5 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KND96093.1 - 0.006 15.9 0.0 0.0085 15.4 0.0 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase Radical_SAM PF04055.21 KND96093.1 - 0.18 12.2 0.0 2.5 8.4 0.0 2.4 2 0 0 2 2 2 0 Radical SAM superfamily SUR7 PF06687.12 KND96095.1 - 4.8e-09 36.1 1.3 8.8e-09 35.3 1.3 1.4 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 KND96095.1 - 0.0067 16.4 4.5 0.013 15.4 4.5 1.4 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 DUF2721 PF11026.8 KND96095.1 - 0.12 12.3 0.1 0.12 12.3 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) RNR_inhib PF08591.10 KND96096.1 - 1.2e-05 26.5 0.1 1.6e-05 26.1 0.1 1.6 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor FAM196 PF15265.6 KND96096.1 - 0.099 12.1 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 FAM196 family Aminotran_3 PF00202.21 KND96098.1 - 1.1e-122 409.7 0.0 1.2e-122 409.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KND96098.1 - 0.0014 17.9 0.0 0.0024 17.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KND96098.1 - 0.0091 15.3 0.0 0.026 13.8 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Pea-VEAacid PF08111.11 KND96098.1 - 0.15 12.4 1.6 0.39 11.1 1.6 1.7 1 0 0 1 1 1 0 Pea-VEAacid family Na_H_Exchanger PF00999.21 KND96099.1 - 1.6e-79 267.5 20.8 1.9e-79 267.2 20.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.10 KND96099.1 - 1.1e-60 206.2 36.1 2.4e-53 182.0 18.1 2.1 1 1 1 2 2 2 2 Alkali metal cation/H+ antiporter Nha1 C terminus Colicin_E5 PF12106.8 KND96099.1 - 0.0075 16.6 0.7 6.3 7.2 0.0 2.5 2 0 0 2 2 2 2 Colicin E5 ribonuclease domain Lys_export PF03956.13 KND96099.1 - 0.031 13.8 6.6 0.071 12.6 0.5 3.0 2 1 1 3 3 3 0 Lysine exporter LysO ChaC PF04752.12 KND96101.1 - 3.3e-52 177.1 0.0 1.1e-51 175.5 0.0 1.7 1 1 0 1 1 1 1 ChaC-like protein TFR_dimer PF04253.15 KND96102.1 - 2.1e-18 66.5 0.0 6.7e-18 64.9 0.0 1.9 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain PA PF02225.22 KND96102.1 - 3.9e-07 30.0 0.1 1.2e-06 28.4 0.1 1.8 1 1 0 1 1 1 1 PA domain Peptidase_M28 PF04389.17 KND96102.1 - 5.1e-07 29.6 0.0 9.5e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Patatin PF01734.22 KND96102.1 - 0.033 14.4 0.3 0.32 11.1 0.3 2.3 1 1 0 1 1 1 0 Patatin-like phospholipase zf-RING_5 PF14634.6 KND96105.1 - 1.1e-06 28.5 3.0 2.5e-06 27.3 3.0 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KND96105.1 - 1.5e-06 28.1 3.6 1.5e-06 28.1 3.6 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KND96105.1 - 3e-06 27.0 5.2 5.7e-06 26.1 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KND96105.1 - 0.00012 22.4 6.8 0.00028 21.2 6.8 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KND96105.1 - 0.00023 20.9 1.7 0.00023 20.9 1.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KND96105.1 - 0.00034 20.4 4.3 0.0012 18.6 4.3 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KND96105.1 - 0.0017 18.2 10.5 1.5 8.7 8.0 3.2 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KND96105.1 - 0.0052 16.9 5.8 0.016 15.4 5.9 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF4174 PF13778.6 KND96105.1 - 0.022 15.2 0.0 0.057 13.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) adh_short PF00106.25 KND96107.1 - 1.8e-29 102.6 0.0 2.3e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND96107.1 - 6.3e-17 61.9 0.0 8.4e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND96107.1 - 7.5e-07 29.2 0.7 2.1e-06 27.8 0.7 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KND96107.1 - 0.0015 18.0 0.1 0.013 15.0 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KND96107.1 - 0.003 16.6 0.4 0.0047 16.0 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1776 PF08643.10 KND96107.1 - 0.012 15.1 1.0 0.017 14.5 1.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF4205 PF13898.6 KND96107.1 - 0.014 14.3 0.4 0.019 13.9 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4205) Diphthamide_syn PF01866.17 KND96108.1 - 4.1e-68 230.1 0.0 7.5e-68 229.2 0.0 1.5 1 1 0 1 1 1 1 Putative diphthamide synthesis protein Nucleoside_tran PF01733.18 KND96111.1 - 1.1e-50 172.8 12.6 4.6e-50 170.8 12.6 1.8 1 1 0 1 1 1 1 Nucleoside transporter Ion_trans_2 PF07885.16 KND96113.1 - 7.3e-27 93.2 29.9 8.2e-16 57.7 7.9 4.4 4 1 1 5 5 5 2 Ion channel Lig_chan PF00060.26 KND96113.1 - 0.045 13.6 10.3 0.19 11.5 0.8 3.1 2 1 1 3 3 3 0 Ligand-gated ion channel NrsF PF06532.11 KND96113.1 - 0.055 13.2 0.4 0.055 13.2 0.4 3.3 4 0 0 4 4 4 0 Negative regulator of sigma F IL32 PF15225.6 KND96113.1 - 0.096 13.1 0.3 0.23 11.8 0.3 1.6 1 0 0 1 1 1 0 Interleukin 32 Ribosomal_S17 PF00366.20 KND96115.1 - 2.7e-19 69.0 1.3 7.1e-19 67.7 1.3 1.8 1 0 0 1 1 1 1 Ribosomal protein S17 DUF2252 PF10009.9 KND96115.1 - 0.094 11.8 3.0 0.13 11.3 3.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Exonuc_VII_L PF02601.15 KND96115.1 - 3.7 7.0 10.2 1.3 8.5 6.9 1.8 1 1 1 2 2 2 0 Exonuclease VII, large subunit PCRF PF03462.18 KND96115.1 - 4.2 7.2 9.5 8.5 6.2 9.5 1.6 1 1 0 1 1 1 0 PCRF domain TPR_1 PF00515.28 KND96117.1 - 5.2e-06 26.0 4.2 6.4e-05 22.6 0.4 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KND96117.1 - 6.2e-06 25.9 3.4 0.00011 22.0 0.3 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KND96117.1 - 0.0016 18.1 1.1 0.0024 17.5 0.1 1.9 2 0 0 2 2 2 1 TPR repeat TPR_9 PF13371.6 KND96117.1 - 0.0048 17.0 0.1 0.0092 16.1 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KND96117.1 - 0.026 14.7 0.5 0.46 10.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat MotY_N PF18393.1 KND96117.1 - 0.063 13.4 0.1 0.16 12.1 0.0 1.7 1 1 1 2 2 2 0 MotY N-terminal domain TPR_14 PF13428.6 KND96117.1 - 0.079 13.8 0.9 0.22 12.4 0.1 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KND96117.1 - 0.091 12.8 0.5 4 7.6 0.0 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 KND96117.1 - 0.12 12.7 0.4 0.54 10.6 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat SNF2_N PF00176.23 KND96118.1 - 9.9e-60 202.1 2.6 1.4e-59 201.6 0.9 1.9 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KND96118.1 - 1.3e-16 60.9 0.0 4.3e-16 59.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND96118.1 - 1.2e-06 28.6 0.6 3.4e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 KND96118.1 - 3e-06 27.0 3.6 6.2e-06 26.0 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KND96118.1 - 0.00012 21.9 3.1 0.00032 20.6 3.3 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KND96118.1 - 0.00022 21.5 5.3 0.0004 20.7 5.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KND96118.1 - 0.00038 20.4 3.8 0.00086 19.3 3.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KND96118.1 - 0.00044 20.1 7.3 0.0091 15.8 7.7 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KND96118.1 - 0.00049 19.9 4.4 0.0012 18.6 4.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KND96118.1 - 0.0016 18.2 2.3 0.0037 17.1 2.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KND96118.1 - 0.28 11.4 7.4 1.3 9.3 7.5 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING FYVE PF01363.21 KND96118.1 - 0.41 10.8 1.5 0.9 9.7 1.5 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-C3HC4_5 PF17121.5 KND96118.1 - 0.55 10.2 4.1 1.2 9.1 4.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KND96118.1 - 1.5 8.6 4.2 3.4 7.5 4.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain V-SNARE PF05008.15 KND96118.1 - 3.1 8.2 6.7 0.65 10.4 0.4 3.0 3 0 0 3 3 2 0 Vesicle transport v-SNARE protein N-terminus Dor1 PF04124.12 KND96119.1 - 1.1e-18 67.0 11.1 2.8e-17 62.4 11.1 2.5 1 1 0 1 1 1 1 Dor1-like family SKA2 PF16740.5 KND96119.1 - 0.067 13.0 1.3 0.42 10.4 0.1 2.7 2 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 vATP-synt_AC39 PF01992.16 KND96120.1 - 1e-106 357.2 0.2 1.2e-106 357.1 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit GCP_N_terminal PF17681.1 KND96120.1 - 0.042 13.5 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal Rad1 PF02144.16 KND96121.1 - 4.4e-50 170.3 0.9 5.3e-50 170.0 0.9 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 AA_permease_2 PF13520.6 KND96123.1 - 1.5e-52 178.8 38.5 1e-51 176.1 38.5 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KND96123.1 - 9.4e-06 24.5 27.2 1.7e-05 23.6 27.2 1.4 1 0 0 1 1 1 1 Amino acid permease SurE PF01975.17 KND96124.1 - 2.5e-11 43.7 0.0 6e-06 26.2 0.0 2.8 2 1 0 2 2 2 2 Survival protein SurE adh_short PF00106.25 KND96125.1 - 8.5e-41 139.6 0.0 1.1e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND96125.1 - 4.5e-31 108.2 0.0 6e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND96125.1 - 2.3e-07 30.9 0.0 4.5e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KND96125.1 - 0.072 12.5 0.0 0.5 9.7 0.0 2.2 2 1 0 2 2 2 0 Fungal family of unknown function (DUF1776) Mur_ligase PF01225.25 KND96125.1 - 0.16 12.3 0.0 0.55 10.6 0.0 1.9 1 1 0 1 1 1 0 Mur ligase family, catalytic domain DUF2370 PF10176.9 KND96126.1 - 3e-78 262.6 0.0 4.3e-78 262.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Sas6_CC PF18594.1 KND96127.1 - 0.086 12.6 0.5 1.8 8.4 0.1 2.2 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain Mito_carr PF00153.27 KND96128.1 - 2.2e-22 78.8 0.3 2.5e-22 78.6 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein TFIIE_alpha PF02002.17 KND96129.1 - 3.4e-18 65.4 2.8 3.6e-18 65.3 0.5 2.0 2 0 0 2 2 2 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 KND96129.1 - 0.00042 19.8 0.5 0.0014 18.1 0.5 2.0 1 1 0 1 1 1 1 TFIIB zinc-binding zf-TFIIB PF13453.6 KND96129.1 - 0.0034 16.7 0.4 0.0073 15.6 0.4 1.5 1 0 0 1 1 1 1 Transcription factor zinc-finger zf_UBZ PF18439.1 KND96129.1 - 0.0097 15.5 0.6 0.53 9.9 0.0 2.7 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger SKIP_SNW PF02731.15 KND96129.1 - 0.012 15.3 0.8 0.035 13.8 0.8 1.8 1 0 0 1 1 1 0 SKIP/SNW domain DUF4946 PF16304.5 KND96129.1 - 0.035 13.8 0.1 0.06 13.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4946) Attacin_N PF03768.15 KND96129.1 - 0.054 13.6 0.4 0.36 11.0 0.1 2.2 2 0 0 2 2 2 0 Attacin, N-terminal region NodS PF05401.11 KND96129.1 - 0.093 12.3 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) zf-FPG_IleRS PF06827.14 KND96129.1 - 0.11 12.4 0.4 4.5 7.2 0.2 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS MAGE_N PF12440.8 KND96129.1 - 3.7 8.3 11.3 0.21 12.3 1.4 2.4 1 1 1 2 2 2 0 Melanoma associated antigen family N terminal LSM14 PF12701.7 KND96131.1 - 0.13 12.4 0.0 0.13 12.4 0.0 1.2 1 1 0 1 1 1 0 Scd6-like Sm domain Forkhead PF00250.18 KND96133.1 - 5.6e-28 97.0 0.1 9.4e-28 96.3 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain G10 PF01125.17 KND96135.1 - 9.3e-58 194.2 9.1 1e-57 194.0 9.1 1.0 1 0 0 1 1 1 1 G10 protein Methyltransf_28 PF02636.17 KND96136.1 - 3e-37 128.7 0.0 6e-37 127.7 0.0 1.5 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Mg_trans_NIPA PF05653.14 KND96138.1 - 1.1e-107 359.6 17.6 1.3e-107 359.3 17.6 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KND96138.1 - 6.7e-06 26.3 5.0 6.7e-06 26.3 5.0 3.8 3 1 0 3 3 3 2 EamA-like transporter family Pkinase PF00069.25 KND96139.1 - 9.8e-19 67.7 0.0 1.8e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KND96139.1 - 3.3e-06 27.7 4.4 0.0094 16.8 0.0 5.0 4 0 0 4 4 4 1 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 KND96139.1 - 1.2e-05 24.7 0.0 2.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 KND96139.1 - 0.0005 20.1 0.0 0.15 12.4 0.0 4.0 3 0 0 3 3 3 1 HEAT repeat APH PF01636.23 KND96139.1 - 0.0056 16.6 0.1 0.01 15.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family HEAT_2 PF13646.6 KND96139.1 - 0.048 14.1 0.0 1.1 9.7 0.0 2.6 1 1 1 2 2 2 0 HEAT repeats UvsW PF11637.8 KND96139.1 - 0.19 11.8 0.0 0.46 10.6 0.0 1.6 1 0 0 1 1 1 0 ATP-dependant DNA helicase UvsW MafB19-deam PF14437.6 KND96140.1 - 0.047 13.4 0.3 0.059 13.1 0.3 1.1 1 0 0 1 1 1 0 MafB19-like deaminase Tfb4 PF03850.14 KND96141.1 - 1.2e-95 320.2 0.8 1.4e-95 320.0 0.8 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 DUF4776 PF16003.5 KND96141.1 - 0.0034 16.5 0.4 0.0054 15.8 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4776) Sin3_corepress PF08295.12 KND96143.1 - 0.053 13.6 0.0 0.067 13.3 0.0 1.1 1 0 0 1 1 1 0 Sin3 family co-repressor SIP1 PF04938.12 KND96145.1 - 6e-19 68.6 0.2 1e-18 67.9 0.2 1.3 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) FliG_N PF14842.6 KND96145.1 - 0.36 11.4 2.6 0.51 10.9 0.9 2.2 2 1 0 2 2 2 0 FliG N-terminal domain UPF0139 PF03669.13 KND96146.1 - 0.0001 22.1 0.4 0.00019 21.2 0.4 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0139) WD40 PF00400.32 KND96147.1 - 1.2e-15 57.6 9.4 0.0068 17.2 0.2 7.9 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND96147.1 - 5e-12 46.0 1.3 3 8.2 0.0 7.3 2 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KND96147.1 - 1.5e-08 34.3 1.4 3.1e-08 33.3 0.3 2.1 2 0 0 2 2 2 1 LisH eIF2A PF08662.11 KND96147.1 - 0.00014 21.8 0.2 0.0036 17.2 0.0 3.0 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Collagen_bind PF05737.12 KND96147.1 - 0.046 13.9 1.6 0.088 13.0 1.6 1.4 1 0 0 1 1 1 0 Collagen binding domain Exo84_C PF16528.5 KND96148.1 - 9.1e-15 55.0 4.1 9.1e-15 55.0 4.1 2.1 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KND96148.1 - 0.0027 17.7 3.3 0.01 15.9 3.3 2.1 1 0 0 1 1 1 1 Vps51/Vps67 DUF2203 PF09969.9 KND96148.1 - 5 7.9 10.4 4.4 8.1 0.5 4.1 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2203) MFS_1 PF07690.16 KND96149.1 - 2.6e-45 154.9 15.5 2.6e-45 154.9 15.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KND96149.1 - 0.00049 19.5 4.7 0.00049 19.5 4.7 2.8 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KND96149.1 - 0.034 12.5 3.3 0.053 11.8 1.7 2.2 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family GAT PF03127.14 KND96152.1 - 0.015 15.5 0.4 0.016 15.5 0.4 1.1 1 0 0 1 1 1 0 GAT domain Acyltransferase PF01553.21 KND96154.1 - 4.6e-23 81.3 0.0 1.1e-22 80.1 0.0 1.6 1 1 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KND96154.1 - 7.5e-09 35.6 0.2 1.3e-06 28.4 0.2 2.5 1 1 0 1 1 1 1 Acyltransferase C-terminus Fig1 PF12351.8 KND96156.1 - 1.4e-36 126.2 8.9 1.8e-36 125.8 8.9 1.0 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 EptA_B_N PF08019.12 KND96156.1 - 2.7 7.9 8.8 0.78 9.6 5.3 1.7 1 1 1 2 2 2 0 Phosphoethanolamine transferase EptA/EptB FAT PF02259.23 KND96157.1 - 4.1e-76 256.4 4.6 1.2e-75 255.0 4.6 1.9 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KND96157.1 - 7.9e-37 127.4 0.1 1.9e-36 126.2 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KND96157.1 - 6.5e-06 25.9 0.1 1.9e-05 24.4 0.1 1.9 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 KND96157.1 - 0.0052 16.7 2.1 0.072 13.0 0.0 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) DUF2013 PF09431.10 KND96157.1 - 0.13 12.4 0.0 0.13 12.4 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2013) PGP_phosphatase PF09419.10 KND96158.1 - 1.4e-70 236.3 0.0 1.7e-70 236.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KND96158.1 - 4.9e-06 26.5 0.0 9.1e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like zf-C3HC4_3 PF13920.6 KND96159.1 - 0.00044 20.0 11.9 0.00044 20.0 11.9 4.1 3 2 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-DNL PF05180.12 KND96160.1 - 1.3e-31 108.3 0.6 1.8e-31 107.9 0.6 1.2 1 0 0 1 1 1 1 DNL zinc finger Zn_ribbon_SprT PF17283.2 KND96160.1 - 0.00027 20.8 0.7 0.65 10.0 0.3 2.2 2 0 0 2 2 2 2 SprT-like zinc ribbon domain zinc_ribbon_4 PF13717.6 KND96160.1 - 0.015 15.2 1.4 0.96 9.4 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.18 KND96160.1 - 0.046 13.6 1.2 7.5 6.5 0.2 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) STAT2_C PF12188.8 KND96160.1 - 0.075 13.0 0.3 0.18 11.7 0.2 1.7 1 1 1 2 2 2 0 Signal transducer and activator of transcription 2 C terminal Zn-ribbon_8 PF09723.10 KND96160.1 - 0.23 11.6 1.7 0.47 10.6 0.5 2.1 2 0 0 2 2 2 0 Zinc ribbon domain ATP11 PF06644.11 KND96161.1 - 1.5e-88 297.1 8.6 1.9e-88 296.8 8.6 1.0 1 0 0 1 1 1 1 ATP11 protein DUF1479 PF07350.12 KND96161.1 - 0.018 13.9 4.2 0.024 13.4 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Peptidase_S49_N PF08496.10 KND96161.1 - 3.9 7.5 8.8 6.4 6.8 8.8 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Mre11_DNA_bind PF04152.14 KND96162.1 - 2.3e-44 151.7 0.5 5.4e-44 150.5 0.5 1.7 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KND96162.1 - 2.8e-11 44.3 0.6 5.1e-11 43.4 0.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HGTP_anticodon2 PF12745.7 KND96163.1 - 1.5e-73 247.6 7.7 1.5e-73 247.6 7.7 3.0 4 0 0 4 4 4 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 KND96163.1 - 8.3e-58 195.8 0.0 1.2e-36 126.4 0.0 3.6 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KND96163.1 - 1.2e-27 96.8 0.0 1.7e-18 66.9 0.0 3.3 3 0 0 3 3 3 2 Protein tyrosine kinase RWD PF05773.22 KND96163.1 - 2.2e-16 60.2 0.6 7.3e-16 58.5 0.6 2.0 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.6 KND96163.1 - 6.7e-08 32.2 0.1 2.2e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 Histidyl-tRNA synthetase Kinase-like PF14531.6 KND96163.1 - 0.0027 17.1 0.0 0.0027 17.1 0.0 2.3 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 KND96163.1 - 0.048 13.6 0.4 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF1682 PF07946.14 KND96163.1 - 0.05 12.8 4.1 0.12 11.6 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Exonuc_VII_L PF02601.15 KND96163.1 - 1.1 8.7 5.5 1.2 8.7 3.7 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit Choline_kinase PF01633.20 KND96164.1 - 2.4e-43 148.2 0.1 6.1e-42 143.6 0.0 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KND96164.1 - 0.0064 16.5 0.0 0.034 14.1 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family PAP2 PF01569.21 KND96165.1 - 2.2e-24 85.7 3.3 2.2e-24 85.7 3.3 1.6 2 0 0 2 2 2 1 PAP2 superfamily DUF3043 PF11241.8 KND96165.1 - 0.28 11.2 0.2 0.56 10.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) PAP2_C PF14360.6 KND96165.1 - 1.8 9.1 5.7 0.43 11.1 0.7 2.3 2 0 0 2 2 2 0 PAP2 superfamily C-terminal PX PF00787.24 KND96167.1 - 4.4e-09 36.3 0.0 1.2e-08 34.9 0.0 1.7 2 0 0 2 2 2 1 PX domain PX PF00787.24 KND96168.1 - 1.1e-06 28.7 0.2 5.3e-06 26.4 0.0 2.2 2 1 0 2 2 2 1 PX domain RecG_N PF17190.4 KND96168.1 - 0.058 14.1 4.9 0.48 11.2 0.4 3.1 2 1 0 2 2 2 0 RecG N-terminal helical domain Yae1_N PF09811.9 KND96169.1 - 1.3e-11 44.0 0.8 1.9e-11 43.5 0.8 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal BTB_2 PF02214.22 KND96170.1 - 0.027 14.8 0.0 0.08 13.3 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain AAA PF00004.29 KND96172.1 - 4.9e-16 59.3 0.0 1.6e-15 57.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 KND96172.1 - 6.2e-15 55.4 0.6 1.3e-14 54.4 0.6 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KND96172.1 - 2.4e-12 46.9 0.1 5e-10 39.4 0.0 2.6 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KND96172.1 - 3.7e-08 33.5 0.0 7.3e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KND96172.1 - 1.7e-05 25.1 0.2 0.00022 21.5 0.0 2.5 2 1 0 2 2 1 1 AAA domain AAA_assoc_2 PF16193.5 KND96172.1 - 3e-05 24.3 0.0 9.4e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 KND96172.1 - 4.1e-05 23.5 0.1 4.9e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KND96172.1 - 4.1e-05 24.0 0.2 0.0034 17.8 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KND96172.1 - 5.4e-05 23.0 0.0 0.00044 20.0 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KND96172.1 - 0.0005 19.3 0.0 0.0012 18.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 KND96172.1 - 0.00058 19.3 0.0 0.025 14.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KND96172.1 - 0.00063 19.8 0.0 0.0025 17.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DNA_pol3_gamma3 PF12169.8 KND96172.1 - 0.0022 17.9 0.1 0.005 16.8 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase III subunits gamma and tau domain III AAA_24 PF13479.6 KND96172.1 - 0.0028 17.4 0.0 0.006 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KND96172.1 - 0.0031 17.9 0.2 0.13 12.6 0.1 3.1 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.6 KND96172.1 - 0.0038 17.3 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KND96172.1 - 0.0092 15.7 0.0 0.034 13.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KND96172.1 - 0.012 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 KND96172.1 - 0.013 15.5 0.0 0.032 14.2 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_3 PF07726.11 KND96172.1 - 0.02 14.8 0.0 0.15 11.9 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KND96172.1 - 0.027 13.7 0.0 0.071 12.3 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 KND96172.1 - 0.052 13.9 0.0 0.16 12.4 0.0 2.0 2 1 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 KND96172.1 - 0.065 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KND96172.1 - 0.072 12.5 0.1 3 7.2 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.6 KND96172.1 - 0.079 13.5 0.3 0.27 11.8 0.0 2.0 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KND96172.1 - 0.11 13.0 0.0 1.1 9.8 0.0 2.3 1 1 1 2 2 2 0 ABC transporter Asp PF00026.23 KND96177.1 - 1e-54 186.1 7.9 1.4e-54 185.7 7.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease zf-SNAP50_C PF12251.8 KND96178.1 - 0.02 14.5 0.0 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal DSPc PF00782.20 KND96179.1 - 1.6e-23 83.0 1.0 1.4e-17 63.8 0.1 3.4 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KND96179.1 - 8.9e-05 22.2 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KND96179.1 - 0.042 14.1 0.1 0.44 10.9 0.0 2.6 2 0 0 2 2 2 0 Rit1 DUSP-like domain DUF3453 PF11935.8 KND96181.1 - 2.3e-40 138.6 0.5 5.2e-40 137.5 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) DUF3826 PF12875.7 KND96181.1 - 0.044 13.9 2.8 0.28 11.3 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3826) DUF4611 PF15387.6 KND96181.1 - 0.72 10.1 6.7 1.9 8.8 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Z1 PF10593.9 KND96181.1 - 8.8 5.8 7.6 1.3 8.5 0.9 2.5 3 0 0 3 3 3 0 Z1 domain KCH PF16944.5 KND96182.1 - 5.8e-72 242.5 16.5 7.3e-72 242.1 16.5 1.1 1 0 0 1 1 1 1 Fungal potassium channel Coiled-coil_56 PF09813.9 KND96183.1 - 0.054 13.6 0.0 0.057 13.5 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 PALP PF00291.25 KND96188.1 - 5e-70 236.2 0.0 5.7e-70 236.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Atx10homo_assoc PF09759.9 KND96190.1 - 1.2e-28 99.1 1.0 1.2e-28 99.1 1.0 2.2 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain DUF5424 PF17462.2 KND96190.1 - 0.08 12.9 0.7 0.2 11.5 0.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5424) Thr_synth_N PF14821.6 KND96191.1 - 2.6e-28 98.0 0.0 7.9e-28 96.5 0.0 1.9 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 KND96191.1 - 2e-14 53.7 0.0 2.8e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Tam41_Mmp37 PF09139.11 KND96192.1 - 1.1e-96 324.0 2.2 1.4e-96 323.7 2.2 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial SAP30_Sin3_bdg PF13867.6 KND96193.1 - 1.1e-10 41.7 0.7 3.9e-08 33.5 0.1 2.4 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 WD40 PF00400.32 KND96194.1 - 3.8e-27 94.0 8.5 3.7e-07 30.7 0.1 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND96194.1 - 3.9e-14 52.7 0.0 0.018 15.4 0.0 5.3 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KND96194.1 - 3.6e-07 29.5 0.5 0.026 13.5 0.1 3.5 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KND96194.1 - 2.3e-05 24.2 4.6 0.53 10.3 0.0 4.2 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KND96194.1 - 4.8e-05 23.3 0.1 0.0033 17.3 0.0 3.3 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KND96194.1 - 0.0079 15.6 0.0 0.15 11.4 0.0 2.7 4 0 0 4 4 4 1 WD40-like domain MMS1_N PF10433.9 KND96194.1 - 0.02 13.5 0.0 0.24 10.0 0.0 2.5 2 1 1 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term CUE PF02845.16 KND96195.1 - 1.4e-05 24.7 0.0 2.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 CUE domain Cue1_U7BR PF18499.1 KND96195.1 - 0.0092 16.0 6.4 0.075 13.1 6.4 2.2 1 1 0 1 1 1 1 Ubc7p-binding region of Cue1 PI31_Prot_N PF11566.8 KND96195.1 - 0.091 12.6 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 PI31 proteasome regulator N-terminal G2BR PF18442.1 KND96195.1 - 1 9.0 7.0 2.1 8.1 7.0 1.5 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) Sugar_tr PF00083.24 KND96197.1 - 2.6e-92 310.0 15.0 3.1e-92 309.8 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND96197.1 - 1.7e-29 102.9 25.4 1.4e-20 73.6 1.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KND96197.1 - 0.0022 16.6 17.2 0.024 13.2 1.5 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein V-SNARE_C PF12352.8 KND96198.1 - 0.033 14.5 0.5 0.16 12.3 0.5 2.2 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Toxin_38 PF14866.6 KND96199.1 - 0.05 13.9 0.3 0.071 13.4 0.3 1.3 1 0 0 1 1 1 0 Potassium channel toxin MFS_1 PF07690.16 KND96200.1 - 3.5e-25 88.7 10.9 3.5e-25 88.7 10.9 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KND96200.1 - 0.0046 16.3 0.3 0.0046 16.3 0.3 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TauE PF01925.19 KND96200.1 - 0.11 12.2 5.5 0.069 12.8 0.5 2.5 2 1 0 2 2 2 0 Sulfite exporter TauE/SafE 5TM-5TMR_LYT PF07694.12 KND96200.1 - 7.3 6.1 12.4 1.5 8.3 3.1 3.5 3 1 1 4 4 4 0 5TMR of 5TMR-LYT Ribosomal_L7Ae PF01248.26 KND96201.1 - 2.6e-27 94.4 0.2 3.7e-27 93.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family LAX PF15681.5 KND96201.1 - 0.035 12.9 0.0 0.051 12.4 0.0 1.2 1 0 0 1 1 1 0 Lymphocyte activation family X ATPase_2 PF01637.18 KND96201.1 - 0.23 11.4 2.3 0.18 11.7 0.8 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea SseC PF04888.12 KND96201.1 - 0.26 10.8 2.9 0.22 11.1 1.7 1.4 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family Adaptin_N PF01602.20 KND96203.1 - 1.3e-96 324.2 11.7 1.9e-96 323.7 11.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 KND96203.1 - 6.7e-56 187.8 0.0 1.7e-55 186.4 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 KND96203.1 - 6.9e-52 175.1 0.7 1.9e-51 173.7 0.7 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region Cnd1 PF12717.7 KND96203.1 - 3.9e-11 43.3 8.5 9.7e-08 32.2 0.2 3.6 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KND96203.1 - 8.8e-09 35.6 0.9 0.00032 21.0 0.0 3.8 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 KND96203.1 - 0.0032 17.6 0.8 0.3 11.5 0.0 4.3 5 0 0 5 5 4 1 HEAT repeat FANCI_S2 PF14676.6 KND96203.1 - 0.004 17.5 4.6 0.005 17.2 0.6 3.0 4 0 0 4 4 4 1 FANCI solenoid 2 AP4E_app_platf PF14807.6 KND96203.1 - 0.0046 17.3 0.4 0.13 12.6 0.0 3.1 2 0 0 2 2 2 1 Adaptin AP4 complex epsilon appendage platform Coatomer_g_Cpla PF16381.5 KND96203.1 - 0.011 15.9 0.1 0.057 13.6 0.0 2.3 2 0 0 2 2 2 0 Coatomer subunit gamma-1 C-terminal appendage platform eIF3_N PF09440.10 KND96203.1 - 0.11 12.9 3.3 0.5 10.8 0.1 2.8 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain DUF5578 PF17741.1 KND96203.1 - 0.66 9.3 5.3 0.71 9.2 0.2 2.8 2 1 1 3 3 3 0 Family of unknown function (DUF5578) DUF4618 PF15397.6 KND96204.1 - 0.021 14.2 0.1 0.053 12.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) LIAS_N PF16881.5 KND96204.1 - 0.12 12.9 0.5 0.94 9.9 0.2 2.5 1 1 1 2 2 2 0 N-terminal domain of lipoyl synthase of Radical_SAM family DUF4594 PF15266.6 KND96204.1 - 0.23 11.8 1.9 0.97 9.8 1.9 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4594) Tnp_22_trimer PF17489.2 KND96204.1 - 0.51 10.3 2.0 1.9 8.5 2.0 2.0 1 0 0 1 1 1 0 L1 transposable element trimerization domain Peptidase_M24 PF00557.24 KND96205.1 - 3.3e-14 53.1 0.0 5.6e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 PHD PF00628.29 KND96206.1 - 6.6e-13 48.3 23.6 1.2e-08 34.7 11.3 2.4 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H_2 PF13832.6 KND96206.1 - 0.18 12.0 6.9 2.6 8.2 3.8 2.4 2 0 0 2 2 2 0 PHD-zinc-finger like domain PHF12_MRG_bd PF16737.5 KND96206.1 - 0.18 11.5 1.4 1.3 8.8 0.0 2.9 3 0 0 3 3 3 0 PHD finger protein 12 MRG binding domain zf-HC5HC2H PF13771.6 KND96206.1 - 0.28 11.5 10.0 0.44 10.8 4.0 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain C1_1 PF00130.22 KND96206.1 - 6.7 6.7 22.5 0.037 13.9 1.5 2.8 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) L51_S25_CI-B8 PF05047.16 KND96207.1 - 3.1e-07 30.2 0.0 4.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ArgJ PF01960.18 KND96208.1 - 1.9e-146 487.7 6.2 2.1e-146 487.5 6.2 1.0 1 0 0 1 1 1 1 ArgJ family MULE PF10551.9 KND96209.1 - 0.15 12.5 0.2 35 4.9 0.0 2.7 2 0 0 2 2 2 0 MULE transposase domain adh_short PF00106.25 KND96210.1 - 4.2e-40 137.3 0.1 5.8e-40 136.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND96210.1 - 6.1e-29 101.2 0.0 8.5e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND96210.1 - 1.4e-06 28.3 0.3 3.3e-05 23.9 0.3 2.2 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KND96210.1 - 0.098 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KND96210.1 - 0.14 11.6 0.1 0.43 10.0 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Hydrolase_6 PF13344.6 KND96210.1 - 0.15 12.2 0.0 2 8.6 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Iwr1 PF08574.10 KND96211.1 - 4.6e-15 56.4 11.0 4.6e-15 56.4 11.0 2.9 3 1 0 3 3 3 1 Transcription factor Iwr1 RNA_pol PF00940.19 KND96212.1 - 1.2e-140 469.0 1.9 1.9e-140 468.4 1.9 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KND96212.1 - 1.8e-21 76.9 0.0 2.4e-19 69.9 0.0 2.5 2 0 0 2 2 2 2 DNA-directed RNA polymerase N-terminal TRAPP PF04051.16 KND96213.1 - 7.3e-37 126.3 0.0 1.2e-36 125.6 0.0 1.3 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component RhoGEF PF00621.20 KND96214.1 - 4e-11 43.5 3.5 7.2e-11 42.7 3.5 1.4 1 0 0 1 1 1 1 RhoGEF domain RRM_1 PF00076.22 KND96216.1 - 5.7e-12 45.3 0.0 4.3e-11 42.5 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CtsR_C PF17727.1 KND96216.1 - 0.024 14.8 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain TFCD_C PF12612.8 KND96216.1 - 1.1 9.1 3.9 0.41 10.5 0.1 1.9 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal Pkinase PF00069.25 KND96218.1 - 1.2e-38 133.0 0.1 1.8e-38 132.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND96218.1 - 6.5e-24 84.6 0.0 8.9e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND96218.1 - 3.1e-07 30.0 0.0 5.3e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KND96218.1 - 0.00022 20.7 0.2 0.0004 19.8 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KND96218.1 - 0.11 11.3 0.1 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase SH3_2 PF07653.17 KND96220.1 - 1.3e-07 31.2 0.0 2.9e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KND96220.1 - 6.5e-07 28.9 0.4 9.8e-06 25.1 0.4 2.5 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KND96220.1 - 0.034 14.0 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain NABP PF07990.12 KND96220.1 - 0.21 11.1 5.6 1.5 8.2 0.9 2.2 2 0 0 2 2 2 0 Nucleic acid binding protein NABP Abhydrolase_1 PF00561.20 KND96221.1 - 2.3e-15 57.0 0.0 3.8e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KND96221.1 - 9.2e-07 28.4 0.0 1.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KND96221.1 - 0.05 14.2 0.0 0.14 12.7 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF1749 PF08538.10 KND96221.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) FAD_binding_6 PF00970.24 KND96224.1 - 7.8e-08 32.6 0.0 4.5e-07 30.1 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KND96224.1 - 0.029 15.0 0.1 15 6.3 0.0 2.6 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4181 PF13789.6 KND96225.1 - 0.026 14.8 0.9 9.8 6.5 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) CBFD_NFYB_HMF PF00808.23 KND96226.1 - 1.2e-10 41.5 0.1 3.1e-10 40.2 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KND96226.1 - 5.6e-06 26.7 0.1 1.1e-05 25.9 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 MRP-L27 PF09809.9 KND96227.1 - 2.2e-28 98.3 0.3 4.6e-28 97.3 0.1 1.6 2 1 0 2 2 2 1 Mitochondrial ribosomal protein L27 DAO PF01266.24 KND96230.1 - 1.9e-28 100.1 0.0 2.2e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KND96230.1 - 0.003 17.7 0.1 0.0076 16.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KND96230.1 - 0.0034 16.7 0.0 0.0091 15.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SNCAIP_SNCA_bd PF16700.5 KND96230.1 - 0.018 14.7 0.1 0.042 13.6 0.1 1.6 1 0 0 1 1 1 0 Synphilin-1 alpha-Synuclein-binding domain Sacchrp_dh_NADP PF03435.18 KND96230.1 - 0.021 15.1 0.0 0.68 10.2 0.0 2.5 2 1 1 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Thi4 PF01946.17 KND96230.1 - 0.032 13.5 1.4 0.034 13.4 0.1 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KND96230.1 - 0.038 14.6 0.1 0.13 12.9 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GRASP55_65 PF04495.14 KND96231.1 - 7.7e-42 142.9 0.0 4.6e-38 130.7 0.0 2.1 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain PfkB PF00294.24 KND96232.1 - 9.6e-18 64.5 0.0 1.2e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KND96232.1 - 4.6e-05 22.9 0.0 7.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase MFS_1 PF07690.16 KND96233.1 - 8.3e-38 130.2 16.7 8.3e-38 130.2 16.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND96233.1 - 1.3e-11 44.1 8.9 1.3e-11 44.1 8.9 3.6 3 1 0 3 3 3 2 Sugar (and other) transporter UCH_C PF18031.1 KND96233.1 - 0.44 10.5 2.6 0.98 9.4 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolases Ank_2 PF12796.7 KND96236.1 - 1.9e-15 57.2 2.7 1.7e-06 28.5 0.3 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KND96236.1 - 7.3e-14 51.5 4.2 5e-05 23.6 0.6 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KND96236.1 - 7.7e-12 45.5 7.1 0.0014 19.1 0.2 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KND96236.1 - 3.2e-11 43.2 6.6 7.4e-05 23.0 0.4 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND96236.1 - 1.1e-10 40.8 3.1 0.00047 20.4 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeat KilA-N PF04383.13 KND96236.1 - 3.7e-05 23.6 3.1 4.5e-05 23.3 0.3 2.5 2 1 0 2 2 2 1 KilA-N domain Kinase-PolyVal PF18762.1 KND96236.1 - 1.1 9.1 5.7 0.15 12.0 1.0 1.9 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins DUF2722 PF10846.8 KND96237.1 - 0.011 14.7 2.7 0.011 14.7 2.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 KND96237.1 - 0.048 13.7 10.3 0.13 12.4 10.3 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 FSAP_sig_propep PF03032.15 KND96237.1 - 0.16 12.1 4.1 0.43 10.7 4.1 1.8 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide Thg1C PF14413.6 KND96237.1 - 0.38 10.9 6.6 0.13 12.4 3.6 1.7 1 1 1 2 2 2 0 Thg1 C terminal domain Presenilin PF01080.17 KND96237.1 - 0.57 8.9 2.6 0.69 8.6 2.6 1.2 1 0 0 1 1 1 0 Presenilin AP-5_subunit_s1 PF15001.6 KND96237.1 - 0.96 9.4 5.8 1.1 9.2 2.7 2.1 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 DUF3682 PF12446.8 KND96237.1 - 3.1 8.3 16.6 6.4 7.3 16.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Aldedh PF00171.22 KND96238.1 - 1.8e-162 541.1 0.0 2e-162 540.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KND96238.1 - 0.0018 17.7 0.0 0.0036 16.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) TPR_12 PF13424.6 KND96238.1 - 0.053 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat UQ_con PF00179.26 KND96241.1 - 1.4e-36 125.2 0.1 1.7e-36 124.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RPN7 PF10602.9 KND96242.1 - 8.6e-52 175.3 4.8 8.6e-52 175.3 4.8 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 KND96242.1 - 3.6e-15 56.4 0.3 3.6e-15 56.4 0.3 2.0 2 1 0 2 2 2 1 PCI domain Peptidase_C2 PF00648.21 KND96242.1 - 0.02 13.9 0.1 5.5 5.9 0.0 2.3 2 0 0 2 2 2 0 Calpain family cysteine protease CSN8_PSD8_EIF3K PF10075.9 KND96242.1 - 0.022 14.7 0.4 0.073 13.0 0.4 2.0 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family Exo5 PF09810.9 KND96242.1 - 0.21 11.0 3.0 0.12 11.8 0.9 1.6 2 0 0 2 2 2 0 Exonuclease V - a 5' deoxyribonuclease Acyl-CoA_dh_1 PF00441.24 KND96244.1 - 2.1e-29 102.7 1.3 3e-29 102.2 1.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KND96244.1 - 2.8e-14 53.7 0.0 5e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KND96244.1 - 1.9e-12 47.2 0.0 4.2e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KND96244.1 - 1.2e-08 35.3 0.2 1.8e-08 34.7 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain LSM PF01423.22 KND96245.1 - 8.3e-15 54.2 0.0 1.2e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 LSM domain TAF1D PF15333.6 KND96246.1 - 0.72 9.6 8.9 0.73 9.5 8.9 1.0 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D GCD14 PF08704.10 KND96248.1 - 4e-78 262.5 0.0 7.3e-78 261.6 0.0 1.4 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KND96248.1 - 0.00045 20.0 0.0 0.00082 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KND96248.1 - 0.0092 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KND96248.1 - 0.062 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family GCD14_N PF14801.6 KND96248.1 - 0.13 12.2 0.0 0.39 10.6 0.0 1.8 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term Actin PF00022.19 KND96249.1 - 4.4e-101 338.4 0.0 2.6e-100 335.9 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KND96249.1 - 0.0021 16.9 0.0 0.0075 15.1 0.0 1.8 1 1 0 1 1 1 1 MreB/Mbl protein Actin_micro PF17003.5 KND96249.1 - 0.11 11.7 0.1 1.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Putative actin-like family Pkinase PF00069.25 KND96250.1 - 2.5e-53 181.1 0.0 4e-53 180.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND96250.1 - 1.9e-23 83.1 0.0 3.2e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KND96250.1 - 0.019 14.6 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KND96250.1 - 0.039 13.5 0.1 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KND96250.1 - 0.04 13.8 0.0 0.75 9.7 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KND96250.1 - 0.041 12.7 0.0 0.041 12.7 0.0 2.0 3 0 0 3 3 3 0 Fungal protein kinase Kinase-like PF14531.6 KND96250.1 - 0.097 12.0 0.0 0.27 10.5 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Peptidase_M16_C PF05193.21 KND96251.1 - 3e-16 59.9 0.0 9.8e-14 51.8 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KND96251.1 - 1.3e-07 31.7 0.0 1.7e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Erf4 PF10256.9 KND96251.1 - 0.058 13.5 0.2 25 5.0 0.0 4.0 3 1 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family DUF3928 PF13065.6 KND96251.1 - 0.26 12.0 1.9 2.6 8.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3928) Mannosyl_trans3 PF11051.8 KND96252.1 - 5.1e-67 226.1 0.1 1.1e-66 225.1 0.0 1.5 2 0 0 2 2 2 1 Mannosyltransferase putative DUF1476 PF07345.11 KND96252.1 - 0.0036 17.7 0.9 0.012 15.9 0.9 1.9 1 0 0 1 1 1 1 ATPase inhibitor subunit zeta Spore_GerAC PF05504.11 KND96252.1 - 3 8.0 8.4 0.73 10.0 4.7 1.9 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal UFD1 PF03152.14 KND96255.1 - 2.8e-24 85.5 0.1 5.6e-24 84.5 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 KND96255.1 - 1.2e-07 31.9 0.3 1.2e-07 31.9 0.3 2.6 2 1 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A PRP21_like_P PF12230.8 KND96255.1 - 0.19 11.6 1.4 2.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein zf-C2H2 PF00096.26 KND96255.1 - 3.2 8.4 17.3 0.048 14.1 1.9 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf_UBZ PF18439.1 KND96255.1 - 4.4 7.0 12.4 2.7 7.6 0.2 4.5 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Peptidase_S8 PF00082.22 KND96257.1 - 5.4e-29 101.4 9.0 8.8e-29 100.7 9.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KND96257.1 - 1.1e-10 42.0 0.1 2.9e-10 40.7 0.1 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 Lectin_N PF03954.14 KND96257.1 - 0.0062 16.3 0.7 0.18 11.5 0.0 2.7 3 0 0 3 3 3 1 Hepatic lectin, N-terminal domain UQ_con PF00179.26 KND96258.1 - 1.4e-49 167.3 0.1 1.6e-49 167.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KND96258.1 - 0.0006 19.5 0.0 0.00073 19.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KND96258.1 - 0.004 17.4 0.0 0.01 16.1 0.0 1.6 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 KND96258.1 - 0.064 13.1 0.0 0.098 12.5 0.0 1.3 1 0 0 1 1 1 0 UEV domain COX4 PF02936.14 KND96259.1 - 1.6e-05 24.9 0.1 4.1e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Med20 PF08612.11 KND96259.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex BCDHK_Adom3 PF10436.9 KND96262.1 - 2.1e-37 128.4 0.4 3.9e-37 127.6 0.4 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KND96262.1 - 9e-08 32.6 0.0 1.2e-06 29.0 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KND96262.1 - 0.00038 20.3 0.0 0.00073 19.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HUN PF08729.10 KND96263.1 - 2.4e-09 37.1 0.1 2.4e-09 37.1 0.1 2.5 2 0 0 2 2 2 1 HPC2 and ubinuclein domain DUF896 PF05979.12 KND96263.1 - 0.014 15.2 6.5 2.9 7.8 3.6 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF896) Kinetochor_Ybp2 PF08568.10 KND96264.1 - 1.8e-139 466.2 12.7 2.4e-139 465.7 12.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin APG12 PF04110.13 KND96265.1 - 1.1e-22 80.2 0.0 2.2e-22 79.3 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin-like autophagy protein Apg12 SUN PF03856.13 KND96266.1 - 8.2e-91 303.8 14.8 8.2e-91 303.8 14.8 1.7 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) Macoilin PF09726.9 KND96266.1 - 0.027 13.1 7.0 0.033 12.8 7.0 1.1 1 0 0 1 1 1 0 Macoilin family zf-MYND PF01753.18 KND96266.1 - 0.071 13.2 1.5 0.17 12.0 1.5 1.5 1 0 0 1 1 1 0 MYND finger Apt1 PF10351.9 KND96266.1 - 0.52 9.1 4.0 0.63 8.8 4.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sporozoite_P67 PF05642.11 KND96266.1 - 2 6.4 14.5 3.4 5.6 14.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Miga PF10265.9 KND96266.1 - 3.8 6.4 4.7 5.3 5.9 4.7 1.1 1 0 0 1 1 1 0 Mitoguardin PI3K_1B_p101 PF10486.9 KND96266.1 - 8.2 4.1 6.8 10 3.7 6.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pkinase PF00069.25 KND96270.1 - 2e-44 151.9 0.5 2.7e-43 148.3 0.5 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND96270.1 - 6.5e-18 65.0 0.0 1.9e-17 63.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KND96270.1 - 0.0011 18.4 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Phasin_2 PF09361.10 KND96276.1 - 0.12 12.6 3.7 5.6 7.3 2.2 2.6 2 0 0 2 2 2 0 Phasin protein XRN_M PF17846.1 KND96279.1 - 9.9e-86 288.4 8.8 9.9e-86 288.4 8.8 2.7 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 KND96279.1 - 2.2e-73 246.7 0.1 2.2e-73 246.7 0.1 2.1 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 KND96279.1 - 3.6e-58 196.5 0.1 3.6e-58 196.5 0.1 2.0 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain Xrn1_D3 PF18194.1 KND96279.1 - 4.4e-31 106.8 1.4 1.3e-30 105.3 1.4 1.9 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 XRN1_D2_D3 PF18334.1 KND96279.1 - 8.9e-27 93.1 0.0 2.7e-26 91.6 0.0 1.9 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KND96279.1 - 2.7e-17 62.6 0.3 5.1e-17 61.7 0.3 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain DUF5526 PF17664.1 KND96279.1 - 0.023 14.2 6.2 0.049 13.2 6.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5526) LicD PF04991.13 KND96279.1 - 5.2 7.1 14.5 2 8.5 2.8 2.9 3 0 0 3 3 3 0 LicD family CHCH PF06747.13 KND96280.1 - 0.0058 16.7 2.3 0.011 15.9 2.3 1.5 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 KND96280.1 - 0.025 14.9 1.4 0.037 14.3 1.4 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COG2 PF06148.11 KND96282.1 - 0.019 15.0 1.7 0.1 12.7 0.2 2.7 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 EzrA PF06160.12 KND96282.1 - 0.1 10.7 0.1 0.15 10.2 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Mito_carr PF00153.27 KND96285.1 - 4.4e-74 244.5 0.5 5.4e-25 87.2 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KND96285.1 - 3.4e-05 23.1 0.7 0.093 12.3 0.1 4.5 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 KND96285.1 - 0.00019 21.2 0.5 2.6 8.0 0.0 4.8 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_6 PF13405.6 KND96285.1 - 0.0088 15.9 14.7 1.6 8.8 0.2 6.8 8 0 0 8 8 8 2 EF-hand domain EF-hand_7 PF13499.6 KND96285.1 - 0.083 13.4 4.4 2.7 8.5 1.2 4.4 3 2 2 5 5 5 0 EF-hand domain pair Bud13 PF09736.9 KND96287.1 - 7.1e-31 107.6 3.0 7.1e-31 107.6 3.0 2.0 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex Gp45_2 PF17470.2 KND96287.1 - 0.032 14.2 0.4 0.066 13.2 0.4 1.5 1 0 0 1 1 1 0 Phage gene product 45.2 APC_u15 PF16636.5 KND96287.1 - 2.1 8.8 13.4 0.12 12.8 2.5 3.3 3 0 0 3 3 3 0 Unstructured region on APC between APC_crr regions 5 and 6 Sde2_N_Ubi PF13019.6 KND96287.1 - 4.7 7.0 13.4 3 7.6 0.5 2.6 2 1 0 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain Nucleoporin_FG PF13634.6 KND96288.1 - 2.6e-20 73.0 128.2 9.5e-07 29.6 39.7 4.8 1 1 4 5 5 5 5 Nucleoporin FG repeat region KxDL PF10241.9 KND96288.1 - 0.02 15.2 1.1 0.15 12.3 0.2 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF948 PF06103.11 KND96288.1 - 0.071 13.4 2.2 0.11 12.7 0.2 2.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) BAR_3 PF16746.5 KND96288.1 - 0.097 12.4 3.4 0.19 11.4 3.3 1.5 1 1 0 1 1 1 0 BAR domain of APPL family GAT PF03127.14 KND96288.1 - 0.34 11.3 2.5 2.3 8.6 0.5 2.6 3 0 0 3 3 3 0 GAT domain BLOC1_2 PF10046.9 KND96288.1 - 1.1 9.6 4.8 21 5.5 1.2 3.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 KND96288.1 - 1.2 9.4 9.2 2.8 8.1 2.0 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KND96288.1 - 1.2 9.2 4.3 12 6.0 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 KND96288.1 - 1.5 8.9 4.9 8.5 6.4 0.4 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Occludin_ELL PF07303.13 KND96288.1 - 2.6 8.8 5.3 24 5.7 0.7 3.0 2 2 0 2 2 2 0 Occludin homology domain DUF16 PF01519.16 KND96288.1 - 4.4 7.8 7.9 11 6.6 0.8 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF745 PF05335.13 KND96288.1 - 5.3 6.7 6.4 3.8 7.2 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) SUIM_assoc PF16619.5 KND96288.1 - 5.4 7.2 16.2 1.4 9.1 1.2 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Asp PF00026.23 KND96290.1 - 1.4e-61 208.7 1.6 1.6e-61 208.4 1.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KND96290.1 - 1.2e-10 41.9 0.1 6.9e-05 23.2 0.0 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KND96290.1 - 0.0018 18.8 0.3 0.091 13.4 0.1 2.7 2 1 0 2 2 2 1 Aspartyl protease SOAR PF16533.5 KND96291.1 - 0.07 13.1 0.1 0.096 12.7 0.1 1.2 1 0 0 1 1 1 0 STIM1 Orai1-activating region YabA PF06156.13 KND96293.1 - 0.00034 21.2 0.8 0.00034 21.2 0.8 2.0 2 0 0 2 2 2 1 Initiation control protein YabA ZapB PF06005.12 KND96293.1 - 0.023 15.2 5.7 0.13 12.8 1.3 2.6 2 0 0 2 2 2 0 Cell division protein ZapB ING PF12998.7 KND96293.1 - 0.27 11.8 5.2 0.18 12.4 2.2 2.3 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding LCD1 PF09798.9 KND96293.1 - 0.78 8.2 5.3 1.1 7.7 5.3 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein KLRAQ PF10205.9 KND96293.1 - 7 7.0 11.0 0.057 13.7 2.1 2.2 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein PUF PF00806.19 KND96295.1 - 1.6e-49 162.9 23.8 1.4e-07 30.8 0.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat SLIDE PF09111.10 KND96295.1 - 0.16 12.0 0.0 0.71 9.9 0.0 2.1 1 1 1 2 2 2 0 SLIDE Sas10_Utp3 PF04000.15 KND96297.1 - 3.3e-11 43.7 3.1 3.3e-11 43.7 3.1 2.4 2 1 0 2 2 1 1 Sas10/Utp3/C1D family Paf1 PF03985.13 KND96297.1 - 0.0049 15.9 9.8 0.0049 15.9 9.8 1.5 2 0 0 2 2 2 1 Paf1 DUF4611 PF15387.6 KND96297.1 - 0.032 14.5 13.0 0.033 14.4 10.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.10 KND96297.1 - 0.033 14.6 16.2 0.1 13.0 16.2 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Astro_capsid_p PF12226.8 KND96297.1 - 0.038 13.2 14.0 0.072 12.2 14.0 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NOA36 PF06524.12 KND96297.1 - 0.068 12.5 12.4 0.13 11.6 12.4 1.4 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.16 KND96297.1 - 0.12 11.5 8.7 0.25 10.5 8.7 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sporozoite_P67 PF05642.11 KND96297.1 - 0.31 9.1 5.9 0.43 8.6 5.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.13 KND96297.1 - 0.5 10.2 14.9 1.6 8.6 14.9 1.9 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF3449 PF11931.8 KND96297.1 - 1.2 8.9 9.9 0.17 11.7 4.7 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) RNA_pol_3_Rpc31 PF11705.8 KND96297.1 - 2 8.6 24.2 0.11 12.8 16.2 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 RXT2_N PF08595.11 KND96297.1 - 2.8 8.0 13.1 0.34 10.9 8.5 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal GEN1_C PF18380.1 KND96297.1 - 5.5 7.9 10.1 1.3 9.9 5.3 2.3 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain RRN3 PF05327.11 KND96297.1 - 9.2 4.7 10.1 15 4.0 10.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ribosomal_S8e PF01201.22 KND96299.1 - 6.5e-46 155.9 0.0 1e-45 155.3 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8e Fungal_trans PF04082.18 KND96300.1 - 3.1e-64 216.6 3.8 5.4e-64 215.8 3.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KND96300.1 - 7.5e-08 32.4 9.4 0.0002 21.6 2.6 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND96300.1 - 2.4e-05 24.8 8.2 0.0049 17.6 1.9 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KND96300.1 - 0.28 11.2 2.2 0.82 9.7 0.6 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Rap1-DNA-bind PF09197.10 KND96301.1 - 0.0057 17.2 0.5 0.024 15.2 0.1 2.1 2 0 0 2 2 2 1 Rap1, DNA-binding T2SSE_N PF05157.15 KND96301.1 - 0.044 14.0 0.9 0.83 9.9 0.1 2.3 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein E, N-terminal domain zf-RING_2 PF13639.6 KND96303.1 - 1.2e-08 35.1 5.5 1.1e-06 28.9 1.8 2.4 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.7 KND96303.1 - 1.7e-08 34.6 4.3 3.6e-08 33.6 1.3 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KND96303.1 - 1.8e-06 27.9 2.3 0.00087 19.3 0.2 2.6 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4 PF00097.25 KND96303.1 - 1.3e-05 24.9 6.0 4.6e-05 23.2 2.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KND96303.1 - 1.4e-05 24.8 6.6 5.2e-05 23.0 2.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KND96303.1 - 3e-05 23.8 2.5 0.00097 18.9 0.8 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KND96303.1 - 8e-05 22.4 3.6 0.001 18.9 0.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KND96303.1 - 0.00066 19.7 1.4 0.0013 18.7 0.5 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KND96303.1 - 0.0015 18.5 5.0 0.012 15.5 1.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain DUF1644 PF07800.12 KND96303.1 - 0.0016 18.5 4.1 0.0078 16.3 0.2 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1644) BIR PF00653.21 KND96303.1 - 0.0087 16.7 0.1 0.0087 16.7 0.1 2.4 3 0 0 3 3 3 1 Inhibitor of Apoptosis domain FANCL_C PF11793.8 KND96303.1 - 0.019 15.1 4.7 0.67 10.2 1.4 3.0 2 1 0 2 2 2 0 FANCL C-terminal domain zf-Di19 PF05605.12 KND96303.1 - 0.024 14.9 0.6 5.6 7.3 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-Nse PF11789.8 KND96303.1 - 0.027 14.3 4.5 0.1 12.4 1.2 3.0 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit YacG PF03884.14 KND96303.1 - 0.075 12.8 2.4 3.4 7.5 0.2 2.6 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG YusW PF14039.6 KND96303.1 - 0.077 13.5 0.6 0.18 12.4 0.6 1.6 1 0 0 1 1 1 0 YusW-like protein Lar_restr_allev PF14354.6 KND96303.1 - 0.11 12.9 0.3 21 5.6 0.0 2.5 2 0 0 2 2 2 0 Restriction alleviation protein Lar DpnI PF06044.12 KND96303.1 - 0.15 11.7 1.4 1.9 8.1 0.1 2.2 2 0 0 2 2 2 0 Dam-replacing family zf-RING_11 PF17123.5 KND96303.1 - 0.15 11.9 2.5 3.9 7.3 0.4 2.7 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_4 PF14570.6 KND96303.1 - 0.54 10.1 3.4 3 7.7 0.5 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 KND96303.1 - 0.87 9.8 4.6 0.18 11.9 0.9 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KND96303.1 - 1.8 8.8 5.4 2.2 8.5 1.7 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zinc_ribbon_4 PF13717.6 KND96303.1 - 3.4 7.7 8.2 2.2 8.3 0.4 3.5 4 0 0 4 4 4 0 zinc-ribbon domain DUF4514 PF14986.6 KND96304.1 - 0.089 12.8 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) CSTF2_hinge PF14327.6 KND96305.1 - 9.5e-22 77.2 3.5 3.9e-21 75.3 3.5 2.1 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KND96305.1 - 7e-10 38.6 0.0 1.2e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KND96305.1 - 4.3e-06 26.2 3.7 4.3e-06 26.2 3.7 3.3 2 1 1 3 3 3 1 Transcription termination and cleavage factor C-terminal TFIIA PF03153.13 KND96305.1 - 9.3 6.1 29.3 14 5.5 29.1 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sulfatase_C PF14707.6 KND96306.1 - 0.018 15.8 0.4 0.018 15.8 0.4 1.9 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase KxDL PF10241.9 KND96306.1 - 0.046 14.0 0.9 0.11 12.7 0.9 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein GLTSCR1 PF15249.6 KND96306.1 - 0.065 13.7 0.1 0.065 13.7 0.1 2.2 2 1 0 2 2 2 0 Conserved region of unknown function on GLTSCR protein FIVAR PF07554.13 KND96306.1 - 0.18 12.6 2.1 2.5 8.9 0.6 2.6 2 0 0 2 2 2 0 FIVAR domain RNA_pol_Rpc34 PF05158.12 KND96307.1 - 2.6e-92 309.8 0.7 2.9e-92 309.6 0.7 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit DUF2326 PF10088.9 KND96307.1 - 0.029 14.1 0.4 1.6 8.5 0.4 2.6 1 1 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2326) UPF0086 PF01868.16 KND96308.1 - 4.8e-20 71.3 0.0 7.5e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 BPL_LplA_LipB PF03099.19 KND96309.1 - 2.1e-06 27.7 0.0 4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF1989 PF09347.10 KND96310.1 - 2.5e-58 196.4 0.0 3.5e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) NAD_binding_2 PF03446.15 KND96312.1 - 7.6e-34 117.2 0.0 1.1e-33 116.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KND96312.1 - 4.6e-17 62.4 0.0 7.4e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KND96312.1 - 0.0018 18.8 0.0 0.0042 17.6 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Nab2 PF11517.8 KND96312.1 - 0.0047 17.2 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) GFO_IDH_MocA PF01408.22 KND96312.1 - 0.056 14.3 0.0 0.85 10.5 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Arrestin_C PF02752.22 KND96313.1 - 2.8e-13 50.5 0.0 2.5e-12 47.4 0.1 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KND96313.1 - 2.7e-05 24.2 0.0 0.0007 19.7 0.0 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain TPR_19 PF14559.6 KND96314.1 - 3.3e-15 56.3 14.8 0.00016 22.1 0.2 7.5 7 2 3 10 10 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 KND96314.1 - 5e-14 52.3 12.2 0.0016 18.7 0.1 7.7 7 3 1 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KND96314.1 - 2.1e-10 40.0 10.2 0.15 12.4 0.0 10.0 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_2 PF07719.17 KND96314.1 - 3.9e-10 39.1 16.2 0.69 10.2 0.0 9.7 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_11 PF13414.6 KND96314.1 - 4.8e-10 39.0 2.6 0.0076 15.9 0.0 5.9 6 0 0 6 6 6 3 TPR repeat TPR_14 PF13428.6 KND96314.1 - 1.1e-08 35.2 0.9 4.7 8.3 0.0 8.4 6 2 3 9 9 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KND96314.1 - 1.6e-08 34.7 6.8 0.00042 20.5 0.6 4.6 4 1 2 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KND96314.1 - 6.1e-08 32.5 10.2 1 9.9 0.0 8.4 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 KND96314.1 - 1.5e-07 30.9 16.1 0.71 9.8 0.0 8.4 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 KND96314.1 - 1.7e-06 28.3 5.0 2.2 9.1 0.2 7.5 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 KND96314.1 - 2.8e-06 27.9 3.6 4.5 8.0 0.1 6.2 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KND96314.1 - 0.0008 19.3 3.6 22 5.4 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 KND96314.1 - 0.0038 17.5 11.5 0.41 11.0 0.1 5.4 4 2 2 6 6 6 1 Tetratricopeptide repeat PPR_2 PF13041.6 KND96314.1 - 0.15 12.3 1.3 0.97 9.7 0.1 3.1 4 0 0 4 4 4 0 PPR repeat family PEP-utilisers_N PF05524.13 KND96314.1 - 0.36 11.0 3.2 1.4 9.1 3.2 2.1 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal TPR_10 PF13374.6 KND96314.1 - 1.2 9.1 3.5 33 4.5 0.3 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat RNase_P_Rpp14 PF01900.19 KND96315.1 - 1.3e-33 115.3 0.0 1.6e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family SPT2 PF08243.11 KND96316.1 - 5.8e-26 91.2 25.0 5.8e-26 91.2 25.0 2.3 2 0 0 2 2 2 1 SPT2 chromatin protein Rit1_C PF17184.4 KND96317.1 - 1.4e-84 283.8 0.0 2e-84 283.3 0.0 1.2 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KND96317.1 - 2.8e-27 95.2 0.2 4.7e-27 94.5 0.2 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain Pox_A32 PF04665.12 KND96317.1 - 0.061 12.8 0.6 0.091 12.2 0.6 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein DUF3217 PF11506.8 KND96317.1 - 0.14 12.2 0.0 2.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3217) FSH1 PF03959.13 KND96318.1 - 1.3e-45 155.7 0.0 1.5e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 KND96318.1 - 0.00022 21.2 0.0 0.00048 20.1 0.0 1.5 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 KND96318.1 - 0.0049 16.7 0.0 0.33 10.7 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DUF2235 PF09994.9 KND96318.1 - 0.0072 15.7 0.0 0.0077 15.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Lipase_3 PF01764.25 KND96318.1 - 0.048 13.5 0.0 0.23 11.3 0.0 1.9 1 1 1 2 2 2 0 Lipase (class 3) Pox_MCEL PF03291.16 KND96321.1 - 1.1e-97 327.2 0.1 1.4e-97 326.8 0.1 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 KND96321.1 - 2.1e-09 38.0 0.0 2.5e-05 24.9 0.0 2.4 1 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KND96321.1 - 9.8e-07 29.5 0.0 3.8e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND96321.1 - 9.9e-06 26.1 0.0 0.18 12.5 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KND96321.1 - 2.7e-05 24.0 0.0 0.00013 21.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 KND96321.1 - 0.0052 16.5 0.0 0.0085 15.8 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Vel1p PF10339.9 KND96321.1 - 0.039 13.3 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Yeast-specific zinc responsive NNMT_PNMT_TEMT PF01234.17 KND96321.1 - 0.12 11.6 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.17 KND96321.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Exo_endo_phos PF03372.23 KND96322.1 - 0.0023 17.5 0.0 0.0078 15.7 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3449 PF11931.8 KND96323.1 - 1.8e-60 203.9 0.8 3.7e-59 199.6 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KND96323.1 - 2.5e-13 50.3 7.4 8e-13 48.7 7.4 1.9 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-met PF12874.7 KND96323.1 - 4.2e-11 42.9 5.6 1.4e-06 28.5 1.5 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KND96323.1 - 1.8e-07 31.2 11.2 7.1e-06 26.2 4.5 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KND96323.1 - 4.9e-05 23.6 1.9 0.0087 16.4 0.6 2.9 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) PRP9_N PF16958.5 KND96323.1 - 0.00047 20.2 10.2 0.00047 20.2 10.2 3.5 3 2 0 3 3 3 1 Pre-mRNA-splicing factor PRP9 N-terminus zf-U1 PF06220.12 KND96323.1 - 0.035 13.9 2.2 0.11 12.3 2.2 1.8 1 0 0 1 1 1 0 U1 zinc finger KIND PF16474.5 KND96323.1 - 0.051 13.5 1.2 0.12 12.2 1.2 1.6 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain zf-BED PF02892.15 KND96323.1 - 0.058 13.4 1.0 1 9.4 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger zf-RRN7 PF11781.8 KND96323.1 - 0.096 12.4 0.4 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-C2H2 PF00096.26 KND96323.1 - 3.8 8.2 5.6 28 5.4 0.3 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND96323.1 - 6 8.0 5.8 20 6.3 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Inv-AAD PF18785.1 KND96324.1 - 2.4e-38 130.9 0.1 5e-38 129.9 0.1 1.6 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase PseudoU_synth_2 PF00849.22 KND96324.1 - 1.6e-31 109.6 0.1 2.5e-31 108.9 0.1 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase dCMP_cyt_deam_1 PF00383.23 KND96324.1 - 2.2e-18 66.0 0.0 5.3e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KND96324.1 - 0.00012 21.9 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase S4 PF01479.25 KND96324.1 - 0.058 13.1 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 S4 domain PalH PF08733.10 KND96325.1 - 8e-77 258.5 18.2 9.7e-77 258.2 18.2 1.1 1 0 0 1 1 1 1 PalH/RIM21 RabGAP-TBC PF00566.18 KND96327.1 - 1.8e-38 132.3 0.1 3.6e-38 131.4 0.1 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Blt1 PF12754.7 KND96328.1 - 0.005 17.2 0.2 0.0094 16.3 0.2 1.5 1 0 0 1 1 1 1 Blt1 N-terminal domain Got1 PF04178.12 KND96329.1 - 3.2e-32 111.3 19.4 4.6e-32 110.8 19.4 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2070 PF09843.9 KND96329.1 - 0.033 12.5 12.4 0.039 12.2 12.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) B PF02216.16 KND96329.1 - 0.081 12.9 0.2 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 B domain DUF4579 PF15158.6 KND96329.1 - 0.63 9.8 4.5 0.25 11.1 2.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) DUF4064 PF13273.6 KND96329.1 - 3.6 7.9 16.1 51 4.2 16.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) NARP1 PF12569.8 KND96330.1 - 9.6e-126 420.7 25.5 1.9e-94 317.4 1.3 4.7 3 3 1 4 4 4 4 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 KND96330.1 - 2.6e-12 45.8 18.5 0.05 13.7 0.0 9.2 9 0 0 9 9 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KND96330.1 - 8.7e-10 38.7 20.6 8.2e-05 22.8 2.2 6.2 4 1 4 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KND96330.1 - 2.3e-07 31.1 1.9 3.2 8.8 0.0 6.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KND96330.1 - 3.1e-07 30.1 17.4 1.7 9.0 0.0 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KND96330.1 - 8e-07 29.6 7.9 0.2 12.3 0.0 7.4 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 KND96330.1 - 0.00056 20.2 11.1 12 6.2 0.0 6.9 5 2 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KND96330.1 - 0.0013 19.1 18.1 0.0098 16.4 0.1 6.5 6 2 1 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 KND96330.1 - 0.0017 18.5 0.2 29 4.9 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Spore_GerAC PF05504.11 KND96330.1 - 0.014 15.7 1.7 0.032 14.4 0.0 2.3 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal TPR_17 PF13431.6 KND96330.1 - 0.022 15.1 6.4 0.54 10.8 0.0 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 KND96330.1 - 0.044 13.9 0.0 0.69 10.0 0.1 2.7 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region TPR_1 PF00515.28 KND96330.1 - 0.09 12.6 25.1 14 5.7 0.0 7.7 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 KND96330.1 - 0.45 10.7 9.3 3.9 7.7 0.0 6.2 7 1 0 7 7 7 0 Tetratricopeptide repeat DUF4358 PF14270.6 KND96330.1 - 0.52 10.6 8.5 6.6 7.1 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4358) TPR_10 PF13374.6 KND96330.1 - 3.2 7.7 10.3 1.4 8.9 0.1 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KND96330.1 - 6.1 7.7 10.4 5.2 7.9 0.1 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat Fungal_trans PF04082.18 KND96333.1 - 8.2e-10 38.2 0.4 2e-09 36.9 0.4 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND96333.1 - 8.5e-10 38.6 11.3 1.5e-09 37.8 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND96334.1 - 1.4e-07 30.8 0.3 1.4e-07 30.8 0.3 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND96334.1 - 2.1e-07 30.9 14.4 2.1e-07 30.9 14.4 2.5 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_1 PF00515.28 KND96335.1 - 5.5e-46 152.6 31.7 1.2e-07 31.2 0.0 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 KND96335.1 - 9.4e-37 122.2 32.2 0.00014 21.7 0.0 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 KND96335.1 - 7.5e-34 115.4 18.0 2.9e-19 68.7 9.0 2.7 2 0 0 2 2 2 2 STI1 domain TPR_11 PF13414.6 KND96335.1 - 8.2e-20 70.2 24.2 0.0003 20.4 0.1 8.0 7 2 1 8 8 8 7 TPR repeat TPR_8 PF13181.6 KND96335.1 - 3.4e-19 67.4 27.7 0.0083 16.3 0.0 9.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 KND96335.1 - 5.2e-18 65.4 5.9 5.4e-05 23.8 0.0 6.1 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KND96335.1 - 2.3e-17 63.0 14.9 4.7e-06 26.8 0.1 7.0 3 3 4 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 KND96335.1 - 3.1e-12 46.8 14.7 0.0065 16.9 0.4 6.7 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KND96335.1 - 3.4e-11 43.0 10.5 3.1 8.9 0.1 8.9 5 2 4 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 KND96335.1 - 1.5e-08 34.7 0.4 0.00042 20.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KND96335.1 - 1.8e-08 34.2 13.2 0.066 13.6 0.0 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 KND96335.1 - 5e-08 32.4 11.6 0.9 9.7 0.0 7.4 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 KND96335.1 - 4.5e-06 26.4 10.6 1.7 8.6 0.2 6.5 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 KND96335.1 - 1.7e-05 25.2 18.4 13 6.7 0.1 8.5 8 0 0 8 8 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KND96335.1 - 0.00061 20.0 12.8 3.8 7.8 0.2 5.3 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF3808 PF10300.9 KND96335.1 - 0.011 14.6 1.5 0.029 13.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) PPR_2 PF13041.6 KND96335.1 - 0.037 14.2 1.7 11 6.3 0.0 4.4 4 1 0 4 4 3 0 PPR repeat family TPM_phosphatase PF04536.14 KND96335.1 - 0.047 13.9 3.0 12 6.1 0.0 3.5 3 0 0 3 3 3 0 TPM domain TPR_21 PF09976.9 KND96335.1 - 0.11 12.2 25.1 0.75 9.5 2.8 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat-like domain DUF357 PF04010.13 KND96335.1 - 0.2 11.7 6.1 1.8 8.7 0.3 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF357) Inhibitor_I9 PF05922.16 KND96335.1 - 0.25 12.0 1.9 0.5 11.1 0.0 2.4 2 0 0 2 2 2 0 Peptidase inhibitor I9 PPR PF01535.20 KND96335.1 - 0.5 10.7 1.7 1.1e+02 3.4 0.0 4.8 5 1 1 6 6 3 0 PPR repeat Fis1_TPR_C PF14853.6 KND96335.1 - 1.2 9.3 10.8 10 6.3 0.1 4.9 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat CDPS PF16715.5 KND96335.1 - 1.3 8.7 4.3 0.74 9.4 0.6 2.4 2 1 1 3 3 3 0 Cyclodipeptide synthase SHNi-TPR PF10516.9 KND96335.1 - 1.3 8.5 12.6 2.4 7.7 0.0 4.6 6 0 0 6 6 6 0 SHNi-TPR bZIP_1 PF00170.21 KND96336.1 - 1.2e-05 25.3 7.8 2.6e-05 24.2 7.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor Cyt-b5 PF00173.28 KND96337.1 - 1.3e-20 73.3 0.0 1.8e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2970 PF11174.8 KND96337.1 - 0.031 14.1 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) UPF0258 PF06789.12 KND96337.1 - 0.28 11.3 0.8 1 9.5 0.5 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0258) ArfGap PF01412.18 KND96339.1 - 8.8e-40 135.4 1.2 1.7e-39 134.5 1.2 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Mito_carr PF00153.27 KND96341.1 - 2.7e-43 145.8 5.5 2.9e-17 62.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Nop14 PF04147.12 KND96342.1 - 1.9e-164 549.2 66.4 2.4e-97 327.2 20.0 2.6 1 1 1 2 2 2 2 Nop14-like family APG9 PF04109.16 KND96343.1 - 7.5e-175 582.5 19.4 9e-175 582.3 19.4 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Epimerase PF01370.21 KND96345.1 - 6e-19 68.5 0.0 8.5e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KND96345.1 - 1.3e-14 53.9 0.0 1.7e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KND96345.1 - 1.1e-08 35.2 0.1 3.4e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KND96345.1 - 7.3e-08 31.9 0.2 0.00099 18.4 0.1 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KND96345.1 - 5.9e-07 29.2 0.2 1.5e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KND96345.1 - 3.9e-06 26.5 0.0 9.2e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KND96345.1 - 0.00023 20.4 0.5 0.00044 19.5 0.1 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KND96345.1 - 0.0033 17.0 0.3 0.0076 15.8 0.1 1.8 2 0 0 2 2 2 1 NmrA-like family adh_short_C2 PF13561.6 KND96345.1 - 0.025 14.1 0.0 0.051 13.1 0.0 1.6 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND96345.1 - 0.054 13.4 0.2 0.37 10.7 0.2 2.2 1 1 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.17 KND96345.1 - 0.086 11.9 0.3 0.4 9.7 0.0 2.2 2 1 0 3 3 3 0 RmlD substrate binding domain Imm63 PF15599.6 KND96345.1 - 0.11 12.9 0.0 0.42 11.1 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 63 ADH_zinc_N PF00107.26 KND96345.1 - 0.12 12.3 0.0 0.36 10.8 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Mito_carr PF00153.27 KND96348.1 - 6.3e-71 234.4 5.3 3.5e-25 87.8 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HAT PF02184.16 KND96348.1 - 1.5 8.8 3.7 1 9.4 0.6 2.2 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat MFS_1 PF07690.16 KND96349.1 - 3.4e-27 95.3 24.3 4.5e-27 94.9 24.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Zip PF02535.22 KND96349.1 - 0.29 10.3 6.1 1.9 7.6 1.6 3.2 3 0 0 3 3 3 0 ZIP Zinc transporter Myb_DNA-binding PF00249.31 KND96352.1 - 0.017 15.3 0.1 5 7.4 0.0 2.6 2 1 0 2 2 2 0 Myb-like DNA-binding domain Thiamine_BP PF01910.17 KND96353.1 - 5.1e-26 90.4 0.2 5.8e-26 90.2 0.2 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Glyco_transf_8 PF01501.20 KND96354.1 - 1.1e-24 87.4 0.2 5.8e-24 85.0 0.2 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KND96354.1 - 0.0011 18.4 0.2 0.0017 17.7 0.2 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Cdh1_DBD_1 PF18196.1 KND96354.1 - 0.045 14.1 0.2 0.31 11.4 0.1 2.3 2 1 1 3 3 3 0 Chromodomain helicase DNA-binding domain 1 COG2 PF06148.11 KND96354.1 - 0.21 11.7 2.3 1.4 9.1 0.4 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Septin PF00735.18 KND96355.1 - 9.4e-109 363.0 0.1 1.1e-108 362.8 0.1 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KND96355.1 - 6.1e-09 36.0 0.0 1.1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KND96355.1 - 2.9e-06 27.3 0.4 7e-06 26.0 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KND96355.1 - 7.6e-05 22.1 0.1 0.00013 21.3 0.1 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 KND96355.1 - 0.00026 20.6 0.1 0.0019 17.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KND96355.1 - 0.0032 17.7 0.0 0.043 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KND96355.1 - 0.0035 17.8 0.1 0.0053 17.2 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 KND96355.1 - 0.004 17.4 0.0 0.0078 16.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KND96355.1 - 0.0045 17.1 0.8 1.2 9.1 0.0 2.4 1 1 1 2 2 2 2 Dynamin family PduV-EutP PF10662.9 KND96355.1 - 0.0049 16.6 0.2 0.078 12.7 0.3 2.6 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 KND96355.1 - 0.0051 16.2 0.1 0.059 12.7 0.0 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region NB-ARC PF00931.22 KND96355.1 - 0.0058 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 KND96355.1 - 0.0088 16.6 0.3 0.02 15.4 0.3 1.6 1 1 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 KND96355.1 - 0.031 13.6 0.1 0.053 12.9 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KND96355.1 - 0.069 12.9 0.1 0.15 11.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 KND96355.1 - 0.082 12.0 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein IIGP PF05049.13 KND96355.1 - 0.095 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Ribosomal_L32p PF01783.23 KND96357.1 - 1.4e-14 54.1 5.3 2.3e-14 53.3 4.3 1.9 2 0 0 2 2 2 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.6 KND96357.1 - 0.0098 15.3 1.4 0.017 14.5 1.4 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_4 PF13717.6 KND96357.1 - 0.016 15.1 1.1 0.028 14.3 0.1 1.9 2 0 0 2 2 2 0 zinc-ribbon domain DUF3656 PF12392.8 KND96357.1 - 0.1 13.2 0.1 0.23 12.1 0.1 1.6 1 1 0 1 1 1 0 Collagenase Elf1 PF05129.13 KND96357.1 - 0.41 10.7 3.3 4 7.5 3.3 2.2 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Cupin_8 PF13621.6 KND96358.1 - 4.8e-12 46.1 0.1 2.2e-11 43.9 0.0 2.1 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 KND96358.1 - 1.8e-08 34.8 0.2 0.00051 20.5 0.1 2.6 2 0 0 2 2 2 2 JmjC domain, hydroxylase F-box-like PF12937.7 KND96358.1 - 2.3e-07 30.6 0.0 7.3e-07 29.0 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KND96358.1 - 0.012 15.5 0.0 0.037 13.9 0.0 1.9 1 0 0 1 1 1 0 F-box domain PNP_phzG_C PF10590.9 KND96360.1 - 6.1e-20 71.0 1.5 1.5e-19 69.7 1.5 1.7 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 KND96360.1 - 2.7e-11 43.5 0.0 4.5e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_red PF03358.15 KND96361.1 - 2.6e-11 43.5 0.0 3.8e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KND96361.1 - 0.00012 21.8 0.0 0.00017 21.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KND96361.1 - 0.081 13.1 0.1 0.97 9.6 0.1 2.3 1 1 0 1 1 1 0 Flavodoxin Pkinase PF00069.25 KND96363.1 - 6.8e-65 219.0 7.1 1.6e-64 217.8 0.1 2.9 2 1 0 2 2 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND96363.1 - 7.5e-34 117.2 0.0 7e-32 110.7 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KND96363.1 - 4.2e-18 64.9 0.0 1.1e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 KND96363.1 - 7.9e-07 28.7 0.0 1.9e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KND96363.1 - 0.00025 20.5 0.0 0.00061 19.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KND96363.1 - 0.023 13.7 0.1 0.023 13.7 0.1 2.6 3 0 0 3 3 3 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KND96363.1 - 0.075 12.1 0.1 0.3 10.1 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 Otopetrin PF03189.13 KND96363.1 - 0.56 9.0 6.3 0.17 10.7 2.6 1.8 2 0 0 2 2 2 0 Otopetrin Pkinase_fungal PF17667.1 KND96363.1 - 1 8.1 0.0 1 8.1 0.0 2.8 3 0 0 3 3 3 0 Fungal protein kinase NPR3 PF03666.13 KND96363.1 - 2.2 7.0 14.9 2.9 6.6 11.4 2.5 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Dicty_REP PF05086.12 KND96363.1 - 3.2 5.6 8.9 5.9 4.7 8.9 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein BRF1 PF07741.13 KND96363.1 - 5.7 7.3 13.0 16 5.9 0.0 3.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain LSM PF01423.22 KND96366.1 - 4.3e-17 61.5 0.4 5.2e-17 61.3 0.4 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KND96366.1 - 3.8e-05 23.8 0.2 4.5e-05 23.5 0.2 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KND96366.1 - 0.0013 18.8 0.2 0.0015 18.6 0.2 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain Hfq PF17209.3 KND96366.1 - 0.0048 16.5 0.1 0.0063 16.1 0.1 1.2 1 0 0 1 1 1 1 Hfq protein COPI_assoc PF08507.10 KND96367.1 - 0.0028 17.7 2.0 0.0033 17.5 2.0 1.1 1 0 0 1 1 1 1 COPI associated protein Ras PF00071.22 KND96368.1 - 4.4e-58 195.5 0.0 5.2e-58 195.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND96368.1 - 8.7e-34 116.3 0.0 1.2e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND96368.1 - 1.3e-14 54.0 0.0 1.7e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KND96368.1 - 3.8e-07 30.2 0.0 5.5e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KND96368.1 - 8.2e-06 25.3 0.1 1e-05 25.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KND96368.1 - 8.9e-06 25.3 0.0 9.8e-05 21.9 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 KND96368.1 - 1.3e-05 24.7 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KND96368.1 - 3.4e-05 23.8 0.0 0.018 15.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KND96368.1 - 0.00086 18.9 0.0 0.0088 15.6 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 KND96368.1 - 0.061 13.1 0.0 0.78 9.5 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KND96368.1 - 0.12 12.8 0.0 0.14 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KND96368.1 - 0.16 11.8 0.0 0.5 10.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain EOS1 PF12326.8 KND96369.1 - 1.7e-42 145.3 16.1 1.4e-32 113.0 8.6 2.7 2 1 1 3 3 3 2 N-glycosylation protein OrfB_IS605 PF01385.19 KND96369.1 - 0.053 13.8 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Probable transposase Ribosomal_S13 PF00416.22 KND96370.1 - 1.3e-17 64.3 1.9 1.6e-15 57.6 1.9 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KND96370.1 - 0.00098 18.0 0.0 0.001 17.9 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) PYNP_C PF07831.13 KND96370.1 - 0.064 12.9 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain TRAUB PF08164.12 KND96371.1 - 1.4e-25 89.6 0.0 1.4e-25 89.6 0.0 2.8 3 1 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KND96371.1 - 2.2e-21 77.0 0.5 2.2e-21 77.0 0.5 3.5 3 2 0 3 3 3 1 Apoptosis antagonizing transcription factor Peptidase_C65 PF10275.9 KND96373.1 - 2.4e-07 30.5 0.0 0.02 14.4 0.0 2.4 1 1 1 2 2 2 2 Peptidase C65 Otubain OTU PF02338.19 KND96373.1 - 3e-07 31.0 0.0 6.1e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Motile_Sperm PF00635.26 KND96373.1 - 0.029 14.2 0.0 0.08 12.8 0.0 1.7 1 0 0 1 1 1 0 MSP (Major sperm protein) domain DWNN PF08783.11 KND96373.1 - 0.095 13.0 0.1 0.24 11.7 0.1 1.6 1 0 0 1 1 1 0 DWNN domain zf-C2H2_jaz PF12171.8 KND96374.1 - 3.4e-08 33.5 2.8 6.3e-08 32.7 2.8 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KND96374.1 - 0.026 14.9 0.0 0.05 13.9 0.0 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KND96374.1 - 0.099 13.5 0.5 0.25 12.3 0.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Ribosomal_L16 PF00252.18 KND96376.1 - 3.6e-41 140.3 0.0 4.5e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RCC1 PF00415.18 KND96378.1 - 9.2e-15 55.0 0.0 0.00073 20.1 0.0 5.6 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KND96378.1 - 9.8e-13 47.5 1.5 0.00028 20.6 0.2 3.8 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat DUF1640 PF07798.11 KND96379.1 - 1.9e-55 187.6 12.2 2.2e-55 187.4 12.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Uds1 PF15456.6 KND96379.1 - 0.017 15.3 4.0 0.017 15.3 4.0 1.9 2 0 0 2 2 2 0 Up-regulated During Septation DUF2267 PF10025.9 KND96379.1 - 0.034 14.4 0.4 0.22 11.8 0.0 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) FlaC_arch PF05377.11 KND96379.1 - 0.034 14.5 4.7 1.1 9.7 0.8 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HalX PF08663.10 KND96379.1 - 0.038 14.3 1.4 1.6 9.1 0.1 2.3 2 0 0 2 2 2 0 HalX domain XhlA PF10779.9 KND96379.1 - 0.1 12.8 10.6 0.4 10.9 0.1 2.9 2 1 1 3 3 3 0 Haemolysin XhlA TraC PF07820.12 KND96379.1 - 0.42 11.0 5.7 2.6 8.4 1.9 2.8 2 1 1 3 3 3 0 TraC-like protein DUF2680 PF10925.8 KND96379.1 - 0.43 10.6 0.2 0.43 10.6 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2680) Fungal_TACC PF12709.7 KND96379.1 - 0.85 10.1 10.5 2.9 8.4 4.6 2.7 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF1451 PF07295.11 KND96379.1 - 1.4 9.0 8.0 7.2 6.6 0.2 2.9 1 1 1 2 2 2 0 Zinc-ribbon containing domain SlyX PF04102.12 KND96379.1 - 1.5 9.5 9.8 33 5.2 0.2 3.5 3 1 1 4 4 4 0 SlyX Mt_ATP-synt_D PF05873.12 KND96379.1 - 2.7 7.8 7.3 0.54 10.1 0.3 2.6 2 1 1 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) Prominin PF05478.11 KND96379.1 - 4 5.3 14.7 0.71 7.8 5.5 1.8 1 1 1 2 2 2 0 Prominin Lectin_N PF03954.14 KND96379.1 - 4.1 7.2 8.3 2.8 7.7 4.6 2.4 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain DUF2203 PF09969.9 KND96379.1 - 5.5 7.7 8.4 2.3e+02 2.5 8.4 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) V-SNARE_C PF12352.8 KND96380.1 - 1.4e-12 47.7 1.2 1.4e-12 47.7 1.2 2.9 3 1 1 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KND96380.1 - 6.7e-08 32.4 3.6 4e-07 29.9 0.0 2.7 2 1 1 3 3 3 1 Sec20 DUF4407 PF14362.6 KND96380.1 - 0.0023 17.4 0.9 0.0031 16.9 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Sigma70_r4 PF04545.16 KND96380.1 - 0.0077 15.7 0.3 0.022 14.3 0.1 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 NYD-SP28 PF14772.6 KND96380.1 - 0.069 13.2 11.8 0.78 9.8 3.8 3.2 2 1 1 3 3 3 0 Sperm tail Katanin_con80 PF13925.6 KND96380.1 - 0.081 13.0 0.3 0.17 11.9 0.3 1.5 1 0 0 1 1 1 0 con80 domain of Katanin TPR_MLP1_2 PF07926.12 KND96380.1 - 0.16 12.0 14.1 1.2 9.2 2.1 3.1 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Syntaxin_2 PF14523.6 KND96380.1 - 0.18 12.2 12.4 3.6 8.0 3.3 2.5 1 1 1 2 2 2 0 Syntaxin-like protein Helo_like_N PF17111.5 KND96380.1 - 0.42 9.9 4.8 0.1 12.0 1.2 1.8 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins OmpH PF03938.14 KND96380.1 - 0.62 10.4 11.6 0.22 11.9 3.2 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FliD_N PF02465.18 KND96380.1 - 1.8 9.3 7.5 0.36 11.5 1.0 2.4 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus HemX PF04375.14 KND96380.1 - 2.6 7.3 14.3 1.7 7.8 2.9 2.0 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase YabA PF06156.13 KND96380.1 - 4 8.1 12.5 2.5 8.8 4.9 2.9 2 2 1 3 3 3 0 Initiation control protein YabA PRKG1_interact PF15898.5 KND96380.1 - 9.7 7.2 13.5 2.1 9.3 4.2 2.6 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Glyco_hydro_17 PF00332.18 KND96381.1 - 3.3e-10 40.1 6.3 5.3e-10 39.4 1.1 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 DUF2076 PF09849.9 KND96381.1 - 1.6 8.7 19.3 0.23 11.4 5.0 3.8 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) Bromodomain PF00439.25 KND96382.1 - 1.8e-32 111.3 0.2 4.2e-15 55.6 0.1 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KND96382.1 - 4.6e-15 55.5 0.0 7.5e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 BAH domain SIR2 PF02146.17 KND96383.1 - 7.9e-41 139.9 0.0 2.2e-40 138.5 0.0 1.6 1 1 0 1 1 1 1 Sir2 family Antimicrobial_1 PF08018.11 KND96386.1 - 0.18 12.0 2.0 0.29 11.3 2.0 1.3 1 0 0 1 1 1 0 Frog antimicrobial peptide MLANA PF14991.6 KND96388.1 - 0.00011 22.5 0.3 0.00018 21.8 0.3 1.3 1 1 0 1 1 1 1 Protein melan-A Phage_holin_2_4 PF16082.5 KND96388.1 - 0.00037 20.2 0.2 0.00055 19.6 0.2 1.2 1 0 0 1 1 1 1 Bacteriophage holin family, superfamily II-like EphA2_TM PF14575.6 KND96388.1 - 0.0046 17.8 0.0 0.0062 17.4 0.0 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain WBP-1 PF11669.8 KND96388.1 - 0.0048 17.5 0.3 0.0062 17.2 0.3 1.1 1 0 0 1 1 1 1 WW domain-binding protein 1 Phage_holin_2_3 PF16080.5 KND96388.1 - 0.095 12.5 0.1 0.39 10.5 0.1 2.0 2 0 0 2 2 2 0 Bacteriophage holin family HP1 NOT2_3_5 PF04153.18 KND96391.1 - 4.3e-32 111.0 0.3 5.5e-32 110.6 0.3 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Metallophos_2 PF12850.7 KND96392.1 - 3.7e-12 46.7 0.0 6.4e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Na_trans_assoc PF06512.13 KND96392.1 - 0.00075 19.8 1.2 0.00085 19.7 1.2 1.1 1 0 0 1 1 1 1 Sodium ion transport-associated MCM_bind PF09739.9 KND96392.1 - 0.0089 14.5 5.8 0.012 14.1 5.8 1.1 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor CDC45 PF02724.14 KND96392.1 - 0.047 12.0 7.4 0.061 11.6 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KND96392.1 - 0.26 9.5 13.3 0.32 9.2 13.3 1.0 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 KND96392.1 - 0.98 9.7 11.8 1.4 9.2 11.8 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RRN3 PF05327.11 KND96392.1 - 1.1 7.8 8.5 1.4 7.4 8.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 KND96392.1 - 1.1 8.6 15.4 1.5 8.2 15.4 1.1 1 0 0 1 1 1 0 SDA1 Choline_transpo PF04515.12 KND96393.1 - 3.2e-74 250.0 23.2 3.2e-74 250.0 23.2 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter Arginase PF00491.21 KND96395.1 - 3.9e-87 292.3 0.2 5e-87 291.9 0.2 1.1 1 0 0 1 1 1 1 Arginase family MFS_1 PF07690.16 KND96397.1 - 5.6e-17 61.7 48.5 5.6e-17 61.7 48.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KND96397.1 - 0.00017 20.3 41.5 0.021 13.4 26.2 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein LRR_4 PF12799.7 KND96398.1 - 1.9e-15 56.7 41.4 7e-05 23.1 1.4 8.7 4 2 6 11 11 11 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KND96398.1 - 2.7e-14 52.7 28.8 0.00046 19.9 3.1 7.2 4 3 3 8 8 8 7 Leucine rich repeat LRR_6 PF13516.6 KND96398.1 - 1.1e-07 31.3 11.5 1.5 9.1 0.1 9.8 11 0 0 11 11 11 1 Leucine Rich repeat FNIP PF05725.12 KND96398.1 - 2e-06 27.8 31.4 0.21 11.8 1.3 7.4 6 1 1 8 8 8 3 FNIP Repeat LRR_5 PF13306.6 KND96398.1 - 0.00094 19.1 1.4 3.7 7.5 0.5 3.9 2 1 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KND96398.1 - 0.001 19.3 33.8 1.5 9.6 1.0 10.4 8 2 1 9 9 9 4 Leucine Rich Repeat LRR_9 PF14580.6 KND96398.1 - 0.0032 17.0 7.6 0.47 9.9 1.2 2.9 2 1 0 2 2 2 2 Leucine-rich repeat EIF_2_alpha PF07541.12 KND96399.1 - 3.4e-38 130.3 0.0 7e-38 129.3 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KND96399.1 - 3.4e-15 56.1 1.5 5.6e-15 55.4 1.5 1.4 1 0 0 1 1 1 1 S1 RNA binding domain LZ3wCH PF18517.1 KND96399.1 - 0.086 13.0 0.0 0.35 11.0 0.0 2.1 1 0 0 1 1 1 0 Leucine zipper with capping helix domain Pkinase PF00069.25 KND96400.1 - 2.4e-05 23.8 0.0 2.9e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND96400.1 - 0.0015 17.9 0.0 0.0017 17.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KND96401.1 - 1.2e-46 159.3 0.0 1.5e-46 158.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND96401.1 - 7.1e-19 68.1 0.0 1.2e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KND96401.1 - 0.0011 18.0 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KND96401.1 - 0.039 13.9 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KND96401.1 - 0.043 12.9 0.1 0.068 12.2 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KND96401.1 - 0.09 11.5 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Rho_GDI PF02115.17 KND96403.1 - 1.5e-16 60.7 0.4 1.6e-16 60.6 0.4 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor PBP5_C PF07943.13 KND96403.1 - 0.022 15.0 1.0 0.038 14.2 1.0 1.4 1 0 0 1 1 1 0 Penicillin-binding protein 5, C-terminal domain Rib PF08428.10 KND96403.1 - 1.2 9.2 4.2 9 6.4 0.2 2.9 1 1 2 3 3 3 0 Rib/alpha-like repeat Par3_HAL_N_term PF12053.8 KND96404.1 - 0.093 13.0 0.0 0.095 12.9 0.0 1.1 1 0 0 1 1 1 0 N-terminal of Par3 and HAL proteins Memo PF01875.17 KND96406.1 - 2.2e-69 233.6 0.0 2.5e-69 233.4 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Adaptin_N PF01602.20 KND96407.1 - 2.2e-80 270.7 6.4 2.8e-80 270.4 6.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KND96407.1 - 1.1e-37 129.5 4.9 2.8e-35 121.8 2.5 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KND96407.1 - 2.4e-10 40.7 6.6 0.0027 18.0 0.2 5.4 5 1 0 5 5 5 3 HEAT repeats HEAT PF02985.22 KND96407.1 - 5.3e-06 26.2 4.8 0.16 12.3 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat RasGEF_N_2 PF14663.6 KND96407.1 - 0.001 19.5 1.6 0.056 13.9 0.2 3.7 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RTP1_C1 PF10363.9 KND96407.1 - 0.0012 19.0 2.2 0.24 11.6 0.1 3.1 2 1 1 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 DUF3361 PF11841.8 KND96407.1 - 0.27 11.2 4.0 36 4.3 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) DEAD PF00270.29 KND96408.1 - 1.1e-24 87.2 0.1 1.3e-23 83.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1998 PF09369.10 KND96408.1 - 2.4e-15 57.0 0.6 2.7e-14 53.7 0.2 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 KND96408.1 - 1.5e-14 54.3 0.0 1.2e-12 48.1 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RPW8 PF05659.11 KND96408.1 - 0.028 14.1 0.1 0.39 10.4 0.0 2.4 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 T2SSE PF00437.20 KND96408.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Cellulase PF00150.18 KND96410.1 - 2.9e-12 46.6 5.2 4.5e-12 46.0 5.2 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Asp PF00026.23 KND96412.1 - 2.1e-104 349.3 0.0 1.4e-102 343.4 0.0 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KND96412.1 - 4.8e-15 56.2 0.6 1.5e-12 48.2 0.6 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KND96412.1 - 0.00031 21.3 0.0 0.11 13.1 0.0 2.6 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KND96412.1 - 0.0007 20.1 0.0 0.14 12.7 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KND96412.1 - 0.023 14.5 0.0 0.11 12.2 0.0 2.1 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal HSP70 PF00012.20 KND96414.1 - 1.1e-265 882.5 15.7 1.3e-265 882.3 15.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KND96414.1 - 1.6e-16 60.1 6.6 6.7e-15 54.7 3.7 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KND96414.1 - 5.4e-05 23.0 0.7 0.00016 21.5 0.0 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF615 PF04751.14 KND96414.1 - 0.11 12.4 3.5 0.31 11.0 3.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF615) FtsA PF14450.6 KND96414.1 - 0.17 12.3 12.9 0.42 11.1 1.9 4.2 4 1 0 4 4 4 0 Cell division protein FtsA HXXSHH PF07586.11 KND96414.1 - 0.25 10.9 4.5 0.44 10.1 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) MRP-S27 PF10037.9 KND96414.1 - 3.6 6.3 14.0 0.81 8.5 9.6 1.9 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 GCR1_C PF12550.8 KND96415.1 - 2.5e-19 69.3 0.1 5.6e-19 68.2 0.1 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes TFIIA PF03153.13 KND96415.1 - 0.00029 21.0 35.9 0.00046 20.3 35.9 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PA26 PF04636.13 KND96415.1 - 0.0041 16.1 5.4 0.0059 15.6 5.4 1.3 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) DUF572 PF04502.13 KND96415.1 - 0.055 13.1 13.4 0.098 12.3 13.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Presenilin PF01080.17 KND96415.1 - 0.059 12.1 15.8 0.077 11.7 15.8 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 KND96415.1 - 0.068 13.0 14.1 0.11 12.3 14.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF775 PF05603.12 KND96415.1 - 0.13 11.8 15.0 0.26 10.8 15.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF2126 PF09899.9 KND96415.1 - 0.18 9.8 7.8 0.24 9.5 7.8 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) TERB2 PF15101.6 KND96415.1 - 0.31 11.1 19.4 0.58 10.2 19.4 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Pex14_N PF04695.13 KND96415.1 - 0.34 11.6 20.4 0.83 10.3 20.4 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ndc1_Nup PF09531.10 KND96415.1 - 0.36 9.5 11.1 0.5 9.0 11.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SLC12 PF03522.15 KND96415.1 - 0.41 9.6 14.4 0.62 9.0 14.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Peptidase_S64 PF08192.11 KND96415.1 - 0.45 9.0 13.8 0.03 12.8 8.6 1.6 2 0 0 2 2 2 0 Peptidase family S64 DUF4407 PF14362.6 KND96415.1 - 1.4 8.2 19.7 0.41 9.9 16.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Hid1 PF12722.7 KND96415.1 - 1.4 6.9 13.2 2 6.5 13.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 KND96415.1 - 1.5 8.8 12.4 2.4 8.1 12.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 KND96415.1 - 1.9 7.6 5.5 2.7 7.1 5.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SID-1_RNA_chan PF13965.6 KND96415.1 - 2.4 6.5 4.0 2.9 6.2 4.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Membralin PF09746.9 KND96415.1 - 4.1 6.3 10.1 7.2 5.5 10.1 1.3 1 0 0 1 1 1 0 Tumour-associated protein MDM10 PF12519.8 KND96415.1 - 4.9 5.9 11.6 7.1 5.4 11.6 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 FAM60A PF15396.6 KND96415.1 - 5.8 6.9 16.1 12 5.8 16.1 1.5 1 0 0 1 1 1 0 Protein Family FAM60A SKA1 PF07160.12 KND96415.1 - 6 6.7 26.3 0.36 10.6 0.6 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 AA_permease PF00324.21 KND96417.1 - 4.2e-121 404.9 37.7 4.2e-121 404.9 37.7 1.4 2 0 0 2 2 2 1 Amino acid permease AA_permease_2 PF13520.6 KND96417.1 - 3.4e-35 121.7 37.3 4.6e-35 121.3 37.3 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KND96419.1 - 1.5e-93 314.0 43.1 1.8e-93 313.7 43.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND96419.1 - 3.5e-26 92.0 48.7 4.2e-26 91.7 48.7 1.1 1 0 0 1 1 1 1 Amino acid permease TNFR_16_TM PF18422.1 KND96419.1 - 7.3 6.6 7.7 0.57 10.2 2.0 2.1 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain SET PF00856.28 KND96420.1 - 6.7e-14 52.6 0.0 1.9e-13 51.2 0.0 1.8 1 1 0 1 1 1 1 SET domain YHS PF04945.13 KND96420.1 - 0.0016 18.5 4.8 0.015 15.4 2.0 2.8 2 0 0 2 2 2 1 YHS domain CwfJ_C_1 PF04677.15 KND96421.1 - 3.8e-26 91.4 0.0 7.3e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KND96421.1 - 7.7e-15 55.6 1.4 7.7e-15 55.6 1.4 1.9 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 Ribosomal_L21e PF01157.18 KND96423.1 - 3.1e-41 139.3 4.9 1.2e-40 137.4 3.5 1.9 2 0 0 2 2 2 1 Ribosomal protein L21e CBF PF03914.17 KND96424.1 - 1.5e-31 109.7 0.4 1.5e-31 109.7 0.4 1.7 2 0 0 2 2 2 1 CBF/Mak21 family Sugar_tr PF00083.24 KND96426.1 - 2.9e-78 263.8 17.4 3.4e-78 263.5 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND96426.1 - 2e-14 53.3 17.8 6e-13 48.4 13.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.12 KND96429.1 - 2.1e-27 95.1 1.8 3.8e-27 94.3 1.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KND96429.1 - 1.8e-22 79.7 0.0 2.9e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KND96429.1 - 0.0004 19.8 0.0 0.00066 19.0 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 KND96429.1 - 0.0022 18.7 0.0 0.004 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Glu_dehyd_C PF16912.5 KND96429.1 - 0.0045 16.5 0.0 0.0069 15.9 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus FAD_binding_3 PF01494.19 KND96429.1 - 0.024 13.9 0.0 0.033 13.4 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain ADH_zinc_N_2 PF13602.6 KND96429.1 - 0.049 14.7 0.0 0.088 13.9 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DUF2105 PF09878.9 KND96430.1 - 0.013 15.3 0.2 0.025 14.3 0.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2105) TPR_2 PF07719.17 KND96431.1 - 0.01 15.9 0.4 7.8 6.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat SicP-binding PF09119.10 KND96431.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 SicP binding Exo5 PF09810.9 KND96436.1 - 9.7e-43 147.1 1.4 1.8e-42 146.1 1.4 1.4 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 KND96436.1 - 1.9e-05 24.7 7.8 0.0019 18.2 0.4 3.1 3 0 0 3 3 3 2 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.17 KND96436.1 - 0.072 13.2 1.6 4.6 7.3 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF83 Citrate_synt PF00285.21 KND96439.1 - 2.1e-100 336.3 0.0 2.4e-100 336.1 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain tRNA-synt_1 PF00133.22 KND96440.1 - 5.4e-163 543.5 0.2 1e-162 542.6 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KND96440.1 - 3e-22 79.2 2.0 5.3e-22 78.4 2.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KND96440.1 - 1.7e-21 76.4 0.0 5.7e-14 51.7 0.0 3.6 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KND96440.1 - 1.9e-05 24.3 0.0 3.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KND96440.1 - 0.0075 15.6 0.0 1.2 8.5 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 KND96440.1 - 0.087 12.7 1.9 0.26 11.2 1.9 1.7 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS SPX PF03105.19 KND96441.1 - 5.7 6.7 28.0 4.2 7.2 13.2 2.2 2 0 0 2 2 2 0 SPX domain Ndc1_Nup PF09531.10 KND96441.1 - 8.8 4.9 18.5 5.5 5.6 4.8 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup zf-RING_4 PF14570.6 KND96443.1 - 3e-16 59.0 7.9 5.8e-16 58.0 7.9 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 KND96443.1 - 2.1e-06 27.5 0.0 0.00038 20.2 0.0 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 KND96443.1 - 0.0001 22.1 3.2 0.00025 20.8 3.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 KND96443.1 - 0.00012 22.0 5.2 0.00067 19.6 1.8 2.5 2 1 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 KND96443.1 - 0.019 14.8 3.4 0.044 13.6 3.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 IL7 PF01415.16 KND96443.1 - 0.023 14.7 1.8 0.023 14.7 1.8 2.1 2 0 0 2 2 2 0 Interleukin 7/9 family Nup35_RRM_2 PF14605.6 KND96443.1 - 0.03 14.3 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-C3HC4 PF00097.25 KND96443.1 - 0.052 13.4 4.7 0.12 12.2 4.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KND96443.1 - 0.35 11.2 4.8 0.78 10.1 4.8 1.6 1 0 0 1 1 1 0 Ring finger domain Pkr1 PF08636.10 KND96444.1 - 4.4e-29 100.4 6.9 5.6e-29 100.1 6.9 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF3397 PF11877.8 KND96444.1 - 0.018 15.3 3.8 0.023 14.9 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3397) DcpS_C PF11969.8 KND96445.1 - 9.6e-19 67.9 0.6 2.1e-18 66.9 0.6 1.5 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding zf-C2HE PF16278.5 KND96445.1 - 1.6e-13 50.9 1.2 8e-13 48.6 1.2 2.1 1 1 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger HIT PF01230.23 KND96445.1 - 2.5e-13 50.6 0.1 5.2e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 HIT domain zf-BED PF02892.15 KND96445.1 - 0.0047 16.9 0.0 0.0097 15.9 0.0 1.5 1 0 0 1 1 1 1 BED zinc finger Yippee-Mis18 PF03226.14 KND96445.1 - 0.08 13.2 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Sugar_tr PF00083.24 KND96446.1 - 2.8e-86 290.2 22.2 3.4e-86 289.9 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND96446.1 - 5.8e-33 114.3 23.6 5.8e-33 114.3 23.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KND96446.1 - 9.6e-05 21.0 4.5 9.6e-05 21.0 4.5 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DSPc PF00782.20 KND96447.1 - 1.8e-25 89.3 0.0 6.4e-25 87.5 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KND96447.1 - 0.0063 16.8 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Rit1 DUSP-like domain Elf1 PF05129.13 KND96447.1 - 0.008 16.2 0.4 0.46 10.6 0.1 2.5 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like Y_phosphatase PF00102.27 KND96447.1 - 0.018 14.7 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase HECT_2 PF09814.9 KND96447.1 - 0.046 12.6 1.7 0.8 8.5 0.1 2.1 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding YwqJ-deaminase PF14431.6 KND96447.1 - 0.071 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 YwqJ-like deaminase HypA PF01155.19 KND96447.1 - 0.18 11.9 0.6 1.2 9.2 0.1 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 KND96447.1 - 0.31 10.7 2.8 10 5.8 0.2 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf_C2H2_10 PF18414.1 KND96447.1 - 0.31 10.6 4.5 0.16 11.5 1.4 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-3CxxC_2 PF17180.4 KND96447.1 - 0.34 11.7 4.3 0.29 11.9 1.3 2.1 2 0 0 2 2 2 0 Zinc-binding domain zinc_ribbon_4 PF13717.6 KND96447.1 - 0.52 10.3 4.0 16 5.5 0.4 2.7 2 0 0 2 2 2 0 zinc-ribbon domain RIG-I_C-RD PF11648.8 KND96447.1 - 0.96 9.7 3.7 53 4.1 3.4 2.4 1 1 1 2 2 2 0 C-terminal domain of RIG-I Apc15p PF05841.11 KND96448.1 - 9.3e-07 29.7 0.0 2.1e-06 28.6 0.0 1.7 2 0 0 2 2 2 1 Apc15p protein H-K_ATPase_N PF09040.11 KND96449.1 - 0.035 14.5 0.0 0.051 14.0 0.0 1.3 1 0 0 1 1 1 0 Gastric H+/K+-ATPase, N terminal domain CTU2 PF10288.9 KND96450.1 - 5.7e-17 62.0 0.2 9.6e-17 61.3 0.2 1.4 1 0 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 Rick_17kDa_Anti PF05433.15 KND96451.1 - 1.6e-05 24.7 18.4 1.6e-05 24.7 18.4 2.0 2 0 0 2 2 2 1 Glycine zipper 2TM domain Bacteriocin_IIc PF10439.9 KND96451.1 - 3.4 7.8 12.4 7.6 6.7 12.4 1.6 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide CHCH PF06747.13 KND96452.1 - 0.00022 21.2 5.5 0.00033 20.7 5.5 1.3 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.13 KND96452.1 - 0.00089 19.6 2.4 0.0016 18.8 2.4 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) DNA_repr_REX1B PF14966.6 KND96453.1 - 0.091 13.4 0.4 1.2 9.8 0.1 2.9 3 0 0 3 3 3 0 DNA repair REX1-B NDUFA12 PF05071.16 KND96456.1 - 1.1e-25 90.3 6.7 1.1e-25 90.3 6.7 1.4 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DS PF01916.17 KND96457.1 - 1.1e-127 425.2 0.0 1.3e-127 425.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Peptidase_M18 PF02127.15 KND96458.1 - 1.8e-139 465.2 0.0 2.1e-139 465.0 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KND96458.1 - 0.00063 18.8 0.1 0.92 8.5 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Ribosomal_S20p PF01649.18 KND96460.1 - 0.11 13.2 1.6 2.4 8.9 0.1 2.5 2 0 0 2 2 2 0 Ribosomal protein S20 RRM_1 PF00076.22 KND96460.1 - 0.12 12.2 0.2 0.49 10.3 0.0 2.0 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spem1 PF15670.5 KND96460.1 - 0.68 9.5 6.0 1.8 8.1 6.0 1.7 1 0 0 1 1 1 0 Spermatid maturation protein 1 G-alpha PF00503.20 KND96461.1 - 7.3e-106 354.3 1.4 9.6e-106 353.9 1.4 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KND96461.1 - 4e-15 55.7 0.1 4.8e-10 39.2 0.0 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KND96461.1 - 0.0019 17.6 0.6 0.69 9.2 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KND96461.1 - 0.0056 16.9 0.3 1.2 9.4 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KND96461.1 - 0.069 12.9 0.0 0.2 11.4 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Pkinase PF00069.25 KND96462.1 - 9.3e-60 202.2 0.0 1.2e-59 201.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND96462.1 - 5.1e-30 104.6 0.0 7.2e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND96462.1 - 0.0019 17.6 0.0 0.0027 17.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KND96462.1 - 0.0067 16.4 0.2 0.014 15.3 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KND96462.1 - 0.038 13.4 0.1 0.075 12.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KND96462.1 - 0.058 13.0 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 RIO1 family SIS PF01380.22 KND96466.1 - 7.2e-64 213.5 0.1 5.3e-34 116.9 0.1 2.2 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KND96466.1 - 1.9e-16 60.4 0.0 3.7e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KND96466.1 - 4.5e-11 42.7 0.0 9.3e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KND96466.1 - 6.6e-05 21.9 0.0 0.00011 21.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 KND96466.1 - 0.17 10.6 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Crp PF00325.20 KND96467.1 - 0.14 11.9 0.1 0.31 10.7 0.0 1.7 1 1 0 1 1 1 0 Bacterial regulatory proteins, crp family DUF155 PF02582.14 KND96468.1 - 1.1e-38 133.1 0.1 1.9e-38 132.3 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 AIG1 PF04548.16 KND96468.1 - 0.085 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Ammonium_transp PF00909.21 KND96470.1 - 8.3e-96 321.1 18.6 9.4e-96 320.9 18.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family CheY-binding PF09078.11 KND96470.1 - 0.032 14.4 0.2 0.064 13.4 0.2 1.4 1 0 0 1 1 1 0 CheY binding HalOD1 PF18545.1 KND96470.1 - 0.037 14.3 0.1 0.071 13.4 0.1 1.4 1 0 0 1 1 1 0 Halobacterial output domain 1 TPP_enzyme_N PF02776.18 KND96473.1 - 3.1e-54 183.2 0.1 6.4e-54 182.1 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KND96473.1 - 2.8e-50 170.1 0.1 3.3e-49 166.6 0.1 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KND96473.1 - 3e-38 130.6 0.5 5.6e-38 129.8 0.5 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 KND96473.1 - 0.00069 19.4 0.3 0.0021 17.8 0.0 1.9 2 0 0 2 2 2 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit DUF1788 PF08747.11 KND96473.1 - 0.014 15.4 0.0 0.064 13.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1788) ZnuA PF01297.17 KND96473.1 - 0.13 11.6 0.1 18 4.6 0.0 2.8 2 1 1 3 3 3 0 Zinc-uptake complex component A periplasmic Zn_clus PF00172.18 KND96476.1 - 1.3e-09 38.0 10.1 2.1e-09 37.3 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40_alt PF14077.6 KND96476.1 - 0.15 12.0 0.7 0.37 10.7 0.7 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif Kinesin_assoc PF16183.5 KND96476.1 - 0.17 12.1 2.6 0.12 12.5 0.4 1.8 2 0 0 2 2 2 0 Kinesin-associated ADH_N PF08240.12 KND96477.1 - 6.2e-26 90.4 0.1 2e-25 88.8 0.0 1.9 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KND96477.1 - 1.9e-25 89.3 0.4 3e-25 88.7 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KND96477.1 - 5.1e-14 52.3 0.1 8e-14 51.6 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KND96477.1 - 5.8e-06 25.8 0.2 1.1e-05 24.9 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KND96477.1 - 0.00012 21.5 0.0 0.0014 18.0 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KND96477.1 - 0.00032 21.2 0.2 0.031 14.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.6 KND96477.1 - 0.0032 18.5 0.0 0.0097 17.0 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 KND96477.1 - 0.017 14.7 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 KND96477.1 - 0.02 14.2 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.19 KND96477.1 - 0.026 13.9 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KND96477.1 - 0.035 13.4 0.0 0.059 12.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KND96477.1 - 0.075 11.7 0.8 0.11 11.2 0.8 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_3 PF03447.16 KND96477.1 - 0.1 13.2 0.1 0.24 12.1 0.1 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain MTS PF05175.14 KND96477.1 - 0.11 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain NAD_binding_7 PF13241.6 KND96477.1 - 0.12 12.8 0.1 0.28 11.6 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Methyltransf_25 PF13649.6 KND96477.1 - 0.14 12.8 0.0 0.34 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain HEXIM PF15313.6 KND96479.1 - 0.0071 16.5 2.7 0.011 16.0 2.7 1.2 1 0 0 1 1 1 1 Hexamethylene bis-acetamide-inducible protein Ribosomal_L30 PF00327.20 KND96482.1 - 2.5e-13 49.7 0.4 3.2e-13 49.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e COA2 PF17051.5 KND96484.1 - 1.9e-06 27.8 0.0 2.1e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 MNE1 PF13762.6 KND96486.1 - 5.5e-23 81.6 3.8 5.5e-23 81.6 3.8 2.8 3 1 0 3 3 3 1 Mitochondrial splicing apparatus component Methyltransf_23 PF13489.6 KND96487.1 - 1e-16 61.2 0.0 1.6e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND96487.1 - 9.2e-12 45.5 0.4 3.5e-10 40.4 0.1 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND96487.1 - 2.7e-10 40.8 0.4 1.6e-07 31.9 0.1 3.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND96487.1 - 8.8e-10 39.2 0.0 3.2e-09 37.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND96487.1 - 9.7e-10 38.4 0.1 1.4e-07 31.4 0.1 2.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KND96487.1 - 0.0021 17.4 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Lon_C PF05362.13 KND96488.1 - 4.4e-47 160.3 0.0 7.8e-47 159.5 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KND96488.1 - 3.1e-26 92.5 1.8 6.1e-26 91.6 0.4 2.2 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KND96488.1 - 7.7e-25 87.8 0.0 2.4e-24 86.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KND96488.1 - 3.5e-07 30.3 0.0 1.9e-06 27.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KND96488.1 - 5.6e-07 29.8 0.0 1.7e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KND96488.1 - 4.6e-05 23.2 0.0 0.00015 21.6 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KND96488.1 - 9.8e-05 22.8 0.0 0.00029 21.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KND96488.1 - 0.00088 19.6 0.0 0.047 14.0 0.0 3.0 1 1 0 1 1 1 1 AAA domain ChlI PF13541.6 KND96488.1 - 0.0011 18.8 0.0 0.0026 17.6 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Rad17 PF03215.15 KND96488.1 - 0.0023 17.9 0.3 0.013 15.5 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 KND96488.1 - 0.0026 18.3 2.3 0.0055 17.3 0.0 2.8 3 0 0 3 3 1 1 AAA domain AAA_3 PF07726.11 KND96488.1 - 0.0028 17.5 0.0 0.0061 16.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KND96488.1 - 0.0059 16.5 0.3 0.064 13.2 0.1 2.4 1 1 1 2 2 2 1 NTPase AAA_14 PF13173.6 KND96488.1 - 0.011 15.8 0.0 0.032 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KND96488.1 - 0.012 15.5 0.1 0.03 14.2 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 KND96488.1 - 0.018 14.2 0.1 0.052 12.7 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 KND96488.1 - 0.026 14.9 0.0 0.084 13.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KND96488.1 - 0.038 13.4 0.0 0.2 11.0 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KND96488.1 - 0.047 12.9 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 KND96488.1 - 0.058 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KND96488.1 - 0.058 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KND96488.1 - 0.06 13.3 0.1 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 KND96488.1 - 0.07 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 KND96488.1 - 0.075 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 KND96488.1 - 0.11 13.0 0.0 0.41 11.2 0.0 2.0 1 0 0 1 1 1 0 ABC transporter TRP PF06011.12 KND96490.1 - 2.1e-150 501.2 25.7 2.6e-150 500.9 25.7 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KND96490.1 - 6e-25 88.2 0.0 1e-24 87.5 0.0 1.4 1 0 0 1 1 1 1 ML-like domain DAOA PF15199.6 KND96493.1 - 0.11 12.9 0.2 0.47 10.9 0.0 2.0 1 1 1 2 2 2 0 D-amino acid oxidase activator RIBIOP_C PF04950.12 KND96494.1 - 1.4e-90 303.6 0.1 1.4e-90 303.6 0.1 2.4 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KND96494.1 - 1.2e-30 105.4 0.0 5.5e-30 103.3 0.0 2.3 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 KND96494.1 - 2.2e-07 30.6 1.6 0.00034 20.2 0.0 3.3 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 KND96494.1 - 8.7e-07 29.2 0.0 3.1e-06 27.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KND96494.1 - 4.7e-06 27.0 0.1 4.7e-06 27.0 0.1 2.2 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KND96494.1 - 1e-05 26.0 0.1 7.5e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KND96494.1 - 1.9e-05 24.9 0.4 7.5e-05 23.0 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.6 KND96494.1 - 0.0011 19.3 0.1 0.0038 17.6 0.1 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KND96494.1 - 0.0016 18.4 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 KND96494.1 - 0.0018 18.9 0.1 0.0018 18.9 0.1 3.7 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KND96494.1 - 0.002 18.5 0.0 0.0066 16.8 0.0 1.9 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 KND96494.1 - 0.0022 17.9 0.5 0.0049 16.8 0.5 1.6 1 0 0 1 1 1 1 NTPase MMR_HSR1 PF01926.23 KND96494.1 - 0.0029 17.7 0.6 0.02 15.0 0.6 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 KND96494.1 - 0.003 17.3 0.0 0.0079 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 KND96494.1 - 0.0032 17.2 0.0 0.0089 15.8 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 KND96494.1 - 0.0033 17.7 0.0 0.016 15.5 0.0 2.3 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KND96494.1 - 0.0042 16.3 0.0 0.012 14.8 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 KND96494.1 - 0.0082 16.7 1.9 0.017 15.6 0.0 2.4 2 0 0 2 2 2 1 ABC transporter Rad17 PF03215.15 KND96494.1 - 0.0086 16.0 0.2 0.051 13.5 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 KND96494.1 - 0.01 15.3 0.2 0.021 14.3 0.2 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KND96494.1 - 0.013 15.5 0.5 0.035 14.1 0.1 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) MobB PF03205.14 KND96494.1 - 0.016 15.1 2.3 0.056 13.3 0.5 2.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_11 PF13086.6 KND96494.1 - 0.019 14.7 0.0 0.019 14.7 0.0 4.1 3 1 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 KND96494.1 - 0.03 13.6 5.6 0.066 12.5 0.1 3.0 2 1 1 3 3 3 0 Zeta toxin TsaE PF02367.17 KND96494.1 - 0.084 12.9 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 KND96494.1 - 0.091 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 KND96494.1 - 0.15 11.6 0.5 0.69 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KND96494.1 - 0.39 10.7 0.0 0.39 10.7 0.0 2.8 4 0 0 4 4 1 0 AAA domain cobW PF02492.19 KND96494.1 - 0.61 9.6 5.3 0.086 12.4 0.5 2.0 2 1 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 KND96494.1 - 9 6.0 6.1 0.83 9.4 0.2 2.3 2 0 0 2 2 1 0 Conserved hypothetical ATP binding protein Cyclin PF08613.11 KND96497.1 - 3.4e-20 73.0 0.1 5.1e-20 72.5 0.1 1.3 1 0 0 1 1 1 1 Cyclin DUF4606 PF15379.6 KND96501.1 - 0.051 13.8 0.1 0.085 13.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) ACPS PF01648.20 KND96506.1 - 4.8e-16 58.9 0.0 5.6e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily GMP_synt_C PF00958.22 KND96507.1 - 1.9e-44 149.6 0.2 4.2e-44 148.5 0.2 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 KND96507.1 - 4.4e-43 147.3 0.0 7.1e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 KND96507.1 - 2.2e-09 36.8 0.1 1.3e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KND96507.1 - 3e-07 30.4 0.2 5.4e-06 26.3 0.2 2.5 1 1 0 1 1 1 1 Peptidase C26 QueC PF06508.13 KND96507.1 - 0.0003 20.3 0.0 0.016 14.7 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KND96507.1 - 0.016 14.1 0.0 0.031 13.1 0.0 1.5 1 0 0 1 1 1 0 tRNA methyl transferase ThiI PF02568.14 KND96507.1 - 0.046 13.3 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) HOASN PF14515.6 KND96507.1 - 0.055 13.9 0.1 0.12 12.8 0.1 1.5 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices ATP_bind_3 PF01171.20 KND96507.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 PP-loop family NLE PF08154.12 KND96509.1 - 1.1e-24 86.8 0.1 1.8e-24 86.0 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 KND96509.1 - 1.1e-24 86.2 6.1 8.4e-07 29.6 0.0 7.1 7 1 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 KND96509.1 - 3.1e-07 29.4 4.0 0.0016 17.2 0.8 2.6 2 1 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KND96509.1 - 0.028 14.7 0.1 1.5 9.2 0.0 3.5 3 2 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain N2227 PF07942.12 KND96510.1 - 6.3e-53 179.7 0.0 8.9e-53 179.2 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein PPTA PF01239.22 KND96512.1 - 3.5e-37 125.1 18.1 8.2e-08 31.7 1.7 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat PSCyt2 PF07583.11 KND96512.1 - 0.21 11.5 3.0 0.49 10.3 0.3 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1549) TPR_2 PF07719.17 KND96512.1 - 2 8.7 7.9 16 5.9 1.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 KND96522.1 - 2e-27 96.2 0.0 9.4e-19 67.8 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KND96522.1 - 4.4e-09 36.0 0.0 1.4e-07 31.1 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KND96522.1 - 0.016 15.1 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KND96522.1 - 0.14 11.5 0.0 25 4.0 0.0 2.9 3 0 0 3 3 3 0 Kinase-like Sugar_tr PF00083.24 KND96524.1 - 6.4e-113 378.0 27.6 7.9e-113 377.7 27.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND96524.1 - 2.6e-27 95.7 35.5 2.6e-23 82.5 22.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 KND96524.1 - 0.082 13.5 1.2 0.27 11.8 1.2 2.0 1 0 0 1 1 1 0 Phage holin family 2 Abhydrolase_1 PF00561.20 KND96525.1 - 6.4e-12 45.7 0.1 7.5e-11 42.1 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KND96525.1 - 2.9e-08 33.3 0.0 1.3e-07 31.1 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KND96525.1 - 0.001 18.9 0.0 0.0039 17.0 0.0 1.9 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KND96525.1 - 0.0014 19.3 0.0 0.027 15.1 0.0 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Cutinase PF01083.22 KND96525.1 - 0.0063 16.5 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Cutinase DUF676 PF05057.14 KND96525.1 - 0.013 15.0 0.0 0.033 13.7 0.0 1.7 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 KND96525.1 - 0.18 11.7 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) MFS_1 PF07690.16 KND96526.1 - 2.1e-40 138.7 20.4 2.1e-40 138.7 20.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily SpoVAB PF13782.6 KND96526.1 - 0.0012 19.1 0.9 0.0035 17.6 0.9 1.8 1 0 0 1 1 1 1 Stage V sporulation protein AB MFS_1 PF07690.16 KND96528.1 - 4.3e-35 121.3 26.4 5.4e-35 121.0 23.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND96528.1 - 1.4e-08 34.1 13.7 3e-08 33.0 13.7 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter SpoVAB PF13782.6 KND96528.1 - 0.84 9.9 7.2 0.095 13.0 0.7 2.6 3 0 0 3 3 3 0 Stage V sporulation protein AB MFS_1 PF07690.16 KND96529.1 - 1.9e-37 129.0 18.6 1.9e-37 129.0 18.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Imm17 PF15562.6 KND96529.1 - 0.041 13.8 4.0 0.12 12.3 0.0 3.1 2 0 0 2 2 2 0 Immunity protein 17 MtrG PF04210.13 KND96533.1 - 0.03 14.2 0.3 0.031 14.1 0.3 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF3027 PF11228.8 KND96534.1 - 0.0044 17.1 0.1 0.0052 16.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3027) CsiV PF10972.8 KND96534.1 - 0.014 15.1 0.6 0.016 15.0 0.6 1.2 1 0 0 1 1 1 0 Peptidoglycan-binding protein, CsiV CENP-O PF09496.10 KND96534.1 - 0.021 14.8 2.1 0.024 14.6 2.1 1.1 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component EPOP PF15223.6 KND96534.1 - 0.063 12.6 4.4 0.078 12.3 4.4 1.1 1 0 0 1 1 1 0 Elongin BC and Polycomb repressive complex 2-associated protein YL1 PF05764.13 KND96534.1 - 4.4 7.4 10.9 5 7.2 10.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF3307 PF11750.8 KND96539.1 - 0.17 12.0 3.0 0.33 11.0 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3307) DUF2235 PF09994.9 KND96545.1 - 6.2e-69 232.5 0.0 7.7e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Peptidase_S9 PF00326.21 KND96545.1 - 0.14 11.6 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Rieske PF00355.26 KND96546.1 - 1.1e-11 44.5 0.0 1.7e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 KND96546.1 - 1.1e-09 38.6 1.7 1.1e-09 38.6 1.7 2.1 2 1 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region HECT PF00632.25 KND96547.1 - 7.7e-78 262.1 0.0 1.5e-77 261.1 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MMS1_N PF10433.9 KND96549.1 - 9.1e-14 51.0 0.0 2e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Nucleopor_Nup85 PF07575.13 KND96550.1 - 4.9e-72 243.3 5.3 6.6e-72 242.9 5.3 1.1 1 0 0 1 1 1 1 Nup85 Nucleoporin Ribosomal_L7Ae PF01248.26 KND96552.1 - 1.7e-26 91.7 0.1 2e-26 91.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KND96552.1 - 0.00027 20.8 0.0 0.00039 20.3 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 KND96552.1 - 0.0015 18.6 0.0 0.0016 18.5 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 Pico_P2B PF01552.17 KND96552.1 - 0.04 14.1 0.0 0.088 13.0 0.0 1.5 1 1 1 2 2 2 0 Picornavirus 2B protein Urb2 PF10441.9 KND96553.1 - 2.9e-48 164.5 3.4 2.9e-48 164.5 3.4 3.3 4 1 0 4 4 4 1 Urb2/Npa2 family TetR_C_8 PF14278.6 KND96553.1 - 0.77 9.9 3.6 67 3.7 0.6 4.6 5 0 0 5 5 5 0 Transcriptional regulator C-terminal region Voltage_CLC PF00654.20 KND96554.1 - 5.5e-82 275.9 25.3 5.5e-82 275.9 25.3 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KND96554.1 - 8.1e-14 51.8 0.8 5.1e-06 26.8 0.1 2.6 2 0 0 2 2 2 2 CBS domain AATase PF07247.12 KND96555.1 - 1e-26 93.6 0.0 5.4e-20 71.4 0.0 2.1 2 0 0 2 2 2 2 Alcohol acetyltransferase Syntaxin_2 PF14523.6 KND96556.1 - 6.6e-17 61.7 2.3 6.6e-17 61.7 2.3 2.7 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KND96556.1 - 1.8e-13 50.2 0.2 3.5e-13 49.3 0.2 1.5 1 0 0 1 1 1 1 SNARE domain Synaptobrevin PF00957.21 KND96556.1 - 0.00022 20.9 0.6 0.00022 20.9 0.6 2.4 2 0 0 2 2 2 1 Synaptobrevin Prominin PF05478.11 KND96556.1 - 0.0033 15.5 7.9 0.004 15.2 7.9 1.2 1 0 0 1 1 1 1 Prominin LAMTOR PF15454.6 KND96556.1 - 0.0074 16.9 7.3 0.96 10.1 0.0 2.9 2 0 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator T2SSF PF00482.23 KND96556.1 - 0.015 15.3 0.6 0.17 11.8 0.1 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Med14 PF08638.11 KND96556.1 - 0.051 13.0 1.7 0.075 12.4 0.3 1.9 2 1 0 2 2 2 0 Mediator complex subunit MED14 Orf78 PF06024.12 KND96556.1 - 0.067 13.5 2.0 0.92 9.8 0.1 2.6 2 0 0 2 2 2 0 Orf78 (ac78) YabA PF06156.13 KND96556.1 - 0.26 11.9 0.2 0.26 11.9 0.2 2.8 2 1 0 2 2 2 0 Initiation control protein YabA CHDCT2 PF08074.11 KND96556.1 - 0.55 10.4 6.0 0.11 12.6 0.5 2.2 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain SOAR PF16533.5 KND96556.1 - 1.4 8.9 7.6 1.1 9.2 5.4 2.0 2 0 0 2 2 2 0 STIM1 Orai1-activating region Syntaxin PF00804.25 KND96556.1 - 2.3 7.8 20.2 0.029 14.0 6.3 2.6 3 0 0 3 3 3 0 Syntaxin Laminin_II PF06009.12 KND96556.1 - 5.1 7.1 10.8 0.77 9.8 4.0 2.3 2 0 0 2 2 2 0 Laminin Domain II Spc7 PF08317.11 KND96556.1 - 8.9 5.1 16.4 1.5 7.6 9.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DNA_pol_B PF00136.21 KND96559.1 - 1.7e-119 399.6 4.6 2.4e-119 399.1 4.6 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KND96559.1 - 2.7e-61 206.5 2.8 5e-61 205.7 2.8 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KND96559.1 - 4.4e-36 124.7 0.0 8.7e-36 123.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KND96559.1 - 1.1e-20 73.5 8.5 1.1e-20 73.5 8.5 2.5 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal Glyoxalase PF00903.25 KND96560.1 - 1.9e-12 47.5 0.0 3.2e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KND96560.1 - 1.5e-05 25.2 0.0 0.0011 19.2 0.0 2.6 3 0 0 3 3 3 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 KND96560.1 - 0.003 17.7 0.0 2.2 8.4 0.0 2.5 2 0 0 2 2 2 2 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal SNF5 PF04855.12 KND96561.1 - 6e-46 157.2 4.3 5.3e-29 101.7 0.0 2.7 2 1 1 3 3 3 2 SNF5 / SMARCB1 / INI1 Cys_Met_Meta_PP PF01053.20 KND96562.1 - 2.2e-68 230.6 0.0 4.2e-68 229.6 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Uricase PF01014.18 KND96563.1 - 4.3e-61 204.9 1.1 2.6e-33 115.1 0.6 2.0 2 0 0 2 2 2 2 Uricase RNB PF00773.19 KND96565.1 - 1.7e-57 195.2 0.1 4.8e-57 193.7 0.1 1.8 1 0 0 1 1 1 1 RNB domain RSN1_7TM PF02714.15 KND96568.1 - 1.4e-88 296.8 21.9 1.4e-88 296.8 21.9 2.1 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KND96568.1 - 2.9e-41 140.8 0.8 2.9e-41 140.8 0.8 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KND96568.1 - 3e-27 96.0 1.8 5.1e-27 95.2 1.8 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KND96568.1 - 1.8e-21 76.1 0.2 4e-21 75.0 0.2 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 KND96568.1 - 0.041 13.7 0.1 0.14 12.0 0.1 1.8 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain Pyrophosphatase PF00719.19 KND96569.1 - 6.8e-54 182.0 0.0 9.5e-54 181.5 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Nup188 PF10487.9 KND96570.1 - 7.1e-245 815.2 27.7 7.1e-245 815.2 27.7 1.5 2 0 0 2 2 2 1 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 KND96570.1 - 2e-13 50.0 1.0 2e-13 50.0 1.0 1.9 2 0 0 2 2 2 1 Nuclear pore protein NUP188 C-terminal domain Cnd1 PF12717.7 KND96570.1 - 1.3 9.1 6.1 0.58 10.2 0.7 3.0 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 GHMP_kinases_N PF00288.26 KND96571.1 - 1.5e-15 57.1 4.2 9.3e-15 54.6 0.4 2.9 2 1 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KND96571.1 - 3.9e-07 30.3 0.0 1.3e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KND96571.1 - 0.00053 19.5 0.2 0.0018 17.8 0.1 2.0 2 0 0 2 2 2 1 Galactokinase galactose-binding signature Mtc PF03820.17 KND96572.1 - 1.7e-122 408.3 0.2 2e-122 408.2 0.2 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier SKG6 PF08693.10 KND96574.1 - 0.00012 21.4 1.9 0.00024 20.4 1.9 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.20 KND96574.1 - 0.09 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain Phage_HK97_TLTM PF06120.11 KND96574.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Tail length tape measure protein EphA2_TM PF14575.6 KND96574.1 - 0.11 13.4 0.0 0.15 12.9 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 KND96574.1 - 0.24 10.2 0.0 0.28 10.0 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF2408 PF10303.9 KND96575.1 - 6.3e-47 159.5 17.8 3e-33 115.3 2.0 5.1 3 2 1 4 4 4 3 Protein of unknown function (DUF2408) Med9 PF07544.13 KND96575.1 - 0.065 13.3 3.6 5.7 7.1 0.1 3.5 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 ACP_PD PF04336.12 KND96575.1 - 0.08 13.4 0.8 12 6.4 0.0 3.7 3 0 0 3 3 3 0 Acyl carrier protein phosphodiesterase DUF724 PF05266.14 KND96575.1 - 3.6 7.4 6.8 6 6.7 1.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Cut8 PF08559.10 KND96576.1 - 2.8e-64 217.0 3.4 3.6e-64 216.7 3.4 1.1 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein XPC-binding PF09280.11 KND96576.1 - 0.1 12.4 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 XPC-binding domain BING4CT PF08149.11 KND96577.1 - 1.5e-39 133.7 0.0 4.8e-36 122.4 0.0 3.1 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.32 KND96577.1 - 5.8e-07 30.1 0.1 0.0022 18.8 0.0 5.4 6 1 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND96577.1 - 3.3e-06 27.3 0.0 0.19 12.1 0.0 4.8 2 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain IFP_35_N PF07334.13 KND96577.1 - 0.76 9.9 3.0 1.9 8.6 3.0 1.7 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DHO_dh PF01180.21 KND96578.1 - 2e-94 316.2 0.0 2.4e-94 315.9 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase DASH_Dam1 PF08653.10 KND96579.1 - 4.9e-13 48.7 1.2 4.9e-13 48.7 1.2 1.9 2 0 0 2 2 2 1 DASH complex subunit Dam1 YjbH PF06082.11 KND96579.1 - 0.041 12.7 0.5 0.053 12.3 0.5 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Nnf1 PF03980.14 KND96579.1 - 0.041 14.2 0.1 0.081 13.3 0.1 1.5 1 0 0 1 1 1 0 Nnf1 DivIC PF04977.15 KND96579.1 - 0.15 11.8 1.8 0.26 11.1 1.8 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF1192 PF06698.11 KND96579.1 - 0.39 10.8 2.6 0.33 11.0 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) GET2 PF08690.10 KND96581.1 - 5.6e-78 262.7 0.1 6.3e-78 262.6 0.1 1.0 1 0 0 1 1 1 1 GET complex subunit GET2 DUF2208 PF09973.9 KND96581.1 - 0.075 12.6 3.2 0.13 11.9 3.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) SGS PF05002.15 KND96581.1 - 0.088 12.9 0.3 12 6.1 0.0 2.5 2 0 0 2 2 2 0 SGS domain SURF1 PF02104.15 KND96582.1 - 1.9e-41 142.2 0.0 3.1e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 SURF1 family Nop PF01798.18 KND96583.1 - 2.2e-86 289.1 0.1 2.2e-86 289.1 0.1 1.8 2 0 0 2 2 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KND96583.1 - 3.5e-21 75.4 1.0 3.5e-21 75.4 1.0 2.6 2 1 0 2 2 1 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 KND96583.1 - 0.0086 16.2 36.7 0.013 15.6 36.7 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 YL1 PF05764.13 KND96583.1 - 0.048 13.8 22.6 0.071 13.2 22.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein RR_TM4-6 PF06459.12 KND96583.1 - 0.32 10.8 15.8 0.49 10.2 15.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RP-C_C PF11800.8 KND96583.1 - 0.85 9.7 7.6 27 4.8 0.0 2.4 2 0 0 2 2 2 0 Replication protein C C-terminal region DDHD PF02862.17 KND96583.1 - 1.4 9.1 5.4 2.2 8.4 5.4 1.4 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 KND96583.1 - 4.2 6.0 9.9 6.8 5.3 9.9 1.3 1 0 0 1 1 1 0 Presenilin DUF1682 PF07946.14 KND96583.1 - 4.6 6.4 21.2 6.7 5.8 21.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Coilin_N PF15862.5 KND96583.1 - 5.2 6.9 25.0 9.8 6.0 25.0 1.4 1 0 0 1 1 1 0 Coilin N-terminus CDC45 PF02724.14 KND96583.1 - 5.6 5.1 19.2 7.6 4.7 19.2 1.2 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 KND96583.1 - 6.9 7.1 17.5 15 6.0 17.5 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF913 PF06025.12 KND96583.1 - 9.9 5.0 9.2 14 4.5 9.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Fungal_trans_2 PF11951.8 KND96585.1 - 7.1e-79 265.4 0.1 1.1e-78 264.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND96585.1 - 3.9e-07 30.1 9.6 7e-07 29.3 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UQ_con PF00179.26 KND96586.1 - 4.2e-43 146.4 0.1 4.6e-43 146.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KND96586.1 - 0.0021 17.8 0.0 0.0025 17.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KND96586.1 - 0.0029 17.9 0.0 0.0045 17.3 0.0 1.3 1 0 0 1 1 1 1 RWD domain Bromodomain PF00439.25 KND96587.1 - 9.8e-17 60.8 0.2 3.5e-16 59.0 0.2 2.0 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 KND96587.1 - 1.2e-09 38.0 0.0 8.8e-09 35.3 0.0 2.4 2 0 0 2 2 2 1 Bromodomain associated GSH_synth_ATP PF03917.17 KND96587.1 - 0.0058 15.5 0.6 0.013 14.3 0.6 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain CENP-T_C PF15511.6 KND96587.1 - 0.065 13.3 0.2 0.84 9.8 0.1 2.6 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold RCC1 PF00415.18 KND96588.1 - 4e-13 49.8 0.1 0.0057 17.3 0.0 4.9 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KND96588.1 - 5.4e-10 39.5 0.6 0.0012 19.0 0.0 3.2 2 1 1 3 3 3 2 BTB/POZ domain RCC1_2 PF13540.6 KND96588.1 - 2.7e-08 33.4 9.1 0.00034 20.3 0.2 4.9 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 KND96588.1 - 0.0059 17.2 0.1 3.7 8.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KND96588.1 - 0.023 15.3 0.1 0.071 13.7 0.1 1.8 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND96588.1 - 0.044 14.3 0.5 3.7 8.4 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.6 KND96588.1 - 0.17 12.2 0.2 5.8 7.4 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DNA_binding_1 PF01035.20 KND96589.1 - 4.1e-22 78.1 0.0 5.4e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Flocculin_t3 PF13928.6 KND96590.1 - 7.2 7.2 12.4 0.64 10.6 5.3 2.3 2 1 0 2 2 2 0 Flocculin type 3 repeat ubiquitin PF00240.23 KND96591.1 - 0.013 15.2 0.0 8.8 6.2 0.0 3.4 3 0 0 3 3 3 0 Ubiquitin family zf-Mss51 PF13824.6 KND96593.1 - 5.7e-17 61.6 2.3 1e-16 60.7 2.3 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 PRKCSH PF07915.13 KND96594.1 - 1.7e-11 44.9 0.6 4.9e-11 43.5 0.6 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Yos9_DD PF17880.1 KND96594.1 - 0.038 14.1 0.0 0.083 13.0 0.0 1.5 1 0 0 1 1 1 0 Yos9 dimerzation domain TBCC_N PF16752.5 KND96595.1 - 0.0017 18.8 4.6 0.0024 18.3 4.6 1.2 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain TBCA PF02970.16 KND96595.1 - 0.02 15.2 4.8 0.024 15.0 4.8 1.2 1 0 0 1 1 1 0 Tubulin binding cofactor A COG5 PF10392.9 KND96595.1 - 0.03 14.5 1.0 0.039 14.1 1.0 1.1 1 0 0 1 1 1 0 Golgi transport complex subunit 5 HSP70 PF00012.20 KND96595.1 - 0.036 12.2 3.1 0.04 12.1 3.1 1.0 1 0 0 1 1 1 0 Hsp70 protein Fzo_mitofusin PF04799.13 KND96595.1 - 0.066 12.8 2.3 0.08 12.5 2.3 1.1 1 0 0 1 1 1 0 fzo-like conserved region ACCA PF03255.14 KND96595.1 - 0.077 12.9 2.0 0.099 12.5 2.0 1.2 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Nbl1_Borealin_N PF10444.9 KND96595.1 - 0.16 11.6 4.4 0.56 9.9 3.8 2.2 1 1 0 1 1 1 0 Nbl1 / Borealin N terminal KIP1 PF07765.12 KND96595.1 - 0.41 10.8 3.3 0.55 10.4 3.3 1.3 1 1 0 1 1 1 0 KIP1-like protein Vpu PF00558.19 KND96595.1 - 4.9 7.0 8.6 3 7.7 2.1 2.1 1 1 1 2 2 2 0 Vpu protein XhlA PF10779.9 KND96595.1 - 5.6 7.3 7.0 14 6.0 1.6 2.1 1 1 0 2 2 2 0 Haemolysin XhlA DUF382 PF04037.13 KND96596.1 - 1.7e-48 163.9 0.3 1.7e-48 163.9 0.3 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 KND96596.1 - 7.4e-13 48.1 0.0 1.4e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 PSP Zn_clus PF00172.18 KND96597.1 - 5.4e-05 23.2 8.0 9.4e-05 22.5 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Molybdopterin PF00384.22 KND96598.1 - 1.5e-67 228.5 0.0 2.7e-65 221.0 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KND96598.1 - 8.8e-21 73.8 0.6 2.7e-20 72.2 0.6 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 KND96598.1 - 4e-15 55.1 0.6 4e-15 55.1 0.6 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 KND96598.1 - 4.3e-15 56.1 0.0 1.2e-14 54.7 0.0 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 KND96598.1 - 1.7e-07 31.1 0.3 1.7e-07 31.1 0.3 2.5 1 1 2 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 KND96598.1 - 0.0016 18.2 0.2 0.037 13.8 0.0 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 KND96598.1 - 0.1 12.4 1.1 3.3 7.7 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain TFX_C PF14601.6 KND96598.1 - 0.14 12.1 0.1 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 DNA_binding protein, TFX, C-term Fer4_19 PF06902.11 KND96598.1 - 0.42 10.7 2.5 7.6 6.7 2.5 2.5 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4_7 PF12838.7 KND96598.1 - 0.57 10.8 2.9 1.6 9.3 0.8 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 KND96598.1 - 8.1 7.2 6.5 1.4 9.6 1.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Lsr2 PF11774.8 KND96600.1 - 0.036 14.2 0.2 1.2 9.3 0.2 2.2 2 0 0 2 2 2 0 Lsr2 Dermcidin PF15291.6 KND96600.1 - 0.16 12.6 0.0 0.23 12.0 0.0 1.2 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide DUF2034 PF10356.9 KND96601.1 - 1.9e-45 154.5 0.0 2.3e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KND96601.1 - 0.00015 21.8 0.1 0.012 15.7 0.0 2.3 2 0 0 2 2 2 2 Restriction endonuclease Glyco_hydro_18 PF00704.28 KND96602.1 - 2.9e-26 92.9 1.8 2.1e-25 90.1 1.8 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 NAD_binding_5 PF07994.12 KND96604.1 - 2.9e-140 467.2 0.1 3.4e-140 467.0 0.1 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KND96604.1 - 1.3e-44 150.9 0.6 2.6e-44 149.9 0.6 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase AMP-binding PF00501.28 KND96605.1 - 1.3e-85 287.5 0.1 1.8e-85 287.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KND96605.1 - 0.002 19.0 0.1 0.0075 17.2 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Asparaginase PF00710.20 KND96606.1 - 4.3e-54 183.0 0.0 5.8e-54 182.5 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KND96606.1 - 4.1e-21 75.3 0.0 2.7e-19 69.5 0.0 2.2 2 0 0 2 2 2 2 Glutaminase/Asparaginase C-terminal domain COX6B PF02297.17 KND96608.1 - 1.1e-21 76.8 5.7 1.3e-21 76.6 5.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb TRAPPC9-Trs120 PF08626.11 KND96609.1 - 0 1051.2 10.4 0 1051.0 10.4 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Proteasome PF00227.26 KND96610.1 - 7e-46 156.1 0.1 8.9e-46 155.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KND96610.1 - 1.5e-13 49.9 0.2 1.5e-13 49.9 0.2 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Aha1_N PF09229.11 KND96611.1 - 1.4e-35 122.5 0.1 2.1e-35 121.9 0.1 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KND96611.1 - 1.7e-16 60.6 0.0 2.7e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DUF2299 PF10061.9 KND96611.1 - 0.034 13.9 0.1 0.051 13.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) DUF4820 PF16091.5 KND96611.1 - 0.041 13.2 1.3 0.063 12.6 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) TerB_C PF15615.6 KND96611.1 - 0.081 13.2 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 TerB-C domain ADH_zinc_N PF00107.26 KND96612.1 - 4.6e-22 78.4 0.3 1.2e-21 77.1 0.3 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KND96612.1 - 3.5e-07 29.9 0.1 7.5e-07 28.8 0.1 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KND96612.1 - 0.0022 19.0 0.0 0.0039 18.3 0.0 1.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KND96612.1 - 0.0039 16.5 0.5 0.0058 16.0 0.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KND96612.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain HycI PF01750.18 KND96612.1 - 0.015 15.1 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase maturation protease UDPG_MGDP_dh_N PF03721.14 KND96612.1 - 0.02 14.5 0.4 0.033 13.8 0.1 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 KND96612.1 - 0.074 13.5 0.1 0.13 12.7 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Iso_dh PF00180.20 KND96613.1 - 1.3e-99 333.6 0.1 1.5e-99 333.4 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Formyl_trans_N PF00551.19 KND96614.1 - 8.7e-45 152.7 1.2 9.9e-44 149.2 1.2 1.9 1 1 0 1 1 1 1 Formyl transferase CNP1 PF08750.11 KND96614.1 - 0.0068 16.4 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 CNP1-like family GTP_EFTU PF00009.27 KND96615.1 - 2.1e-68 229.7 0.7 2.9e-68 229.3 0.7 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KND96615.1 - 5.8e-33 113.2 0.0 2.2e-32 111.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KND96615.1 - 3.6e-21 75.0 0.0 8.8e-21 73.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KND96615.1 - 4.4e-13 49.4 0.1 1.2e-12 48.0 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KND96615.1 - 8.2e-13 48.2 0.0 2.9e-12 46.5 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KND96615.1 - 4.4e-05 23.5 0.3 0.0001 22.3 0.3 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KND96615.1 - 0.085 12.6 1.1 0.66 9.7 0.5 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Cu_amine_oxid PF01179.20 KND96618.1 - 2.2e-143 478.1 0.0 2.8e-143 477.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KND96618.1 - 3e-24 85.3 0.1 7.7e-24 84.0 0.1 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KND96618.1 - 5.2e-18 65.1 0.1 1.1e-17 64.0 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain RNA_Me_trans PF04252.13 KND96619.1 - 4.8e-77 258.1 0.0 5.4e-77 257.9 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase DDHD PF02862.17 KND96620.1 - 3.9e-47 161.3 0.0 3.9e-47 161.3 0.0 2.3 2 1 0 2 2 2 1 DDHD domain WWE PF02825.20 KND96620.1 - 8e-06 26.4 5.0 5.3e-05 23.7 1.8 3.2 2 1 1 3 3 3 1 WWE domain Hydrolase_4 PF12146.8 KND96620.1 - 0.1 11.9 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 KND96620.1 - 0.13 12.0 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 KND96620.1 - 0.16 11.8 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) DUF1689 PF07954.11 KND96621.1 - 2e-20 73.7 0.1 2.8e-20 73.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) Pec_lyase PF09492.10 KND96621.1 - 0.055 12.8 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 Pectic acid lyase tRNA-synt_2b PF00587.25 KND96622.1 - 8.5e-35 120.3 0.0 1.5e-34 119.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KND96622.1 - 3.3e-17 62.4 0.9 3.3e-17 62.4 0.9 2.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA_SAD PF07973.14 KND96622.1 - 1.6e-12 47.3 0.0 4.2e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 KND96622.1 - 4.3e-12 45.9 0.0 1.2e-11 44.5 0.0 1.8 2 0 0 2 2 2 1 TGS domain Ribosomal_L14 PF00238.19 KND96623.1 - 1.4e-47 160.7 0.2 1.6e-47 160.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e UPF0029 PF01205.19 KND96624.1 - 2.7e-28 98.4 0.0 3e-28 98.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 FAD-oxidase_C PF02913.19 KND96625.1 - 1.5e-58 198.3 0.0 2.1e-58 197.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KND96625.1 - 2.2e-35 121.4 0.1 4.1e-35 120.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DUF1402 PF07182.11 KND96625.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1402) AMP-binding PF00501.28 KND96626.1 - 4e-74 249.7 0.0 2.5e-73 247.1 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme Flavin_Reduct PF01613.18 KND96627.1 - 5.1e-18 65.6 0.0 7.4e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain DHquinase_II PF01220.19 KND96628.1 - 6.4e-60 200.8 0.4 7.1e-60 200.7 0.4 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Peripla_BP_1 PF00532.21 KND96628.1 - 0.021 14.3 0.1 0.027 13.9 0.1 1.1 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family PDZ_4 PF17816.1 KND96628.1 - 0.039 14.4 0.0 0.05 14.0 0.0 1.1 1 0 0 1 1 1 0 PDZ domain PAC2 PF09754.9 KND96629.1 - 1e-21 77.9 0.2 1.5e-21 77.4 0.2 1.2 1 0 0 1 1 1 1 PAC2 family CLP1_P PF16575.5 KND96629.1 - 0.17 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AFT PF08731.11 KND96630.1 - 1.7e-22 79.9 1.1 1.8e-10 41.2 0.3 2.3 1 1 1 2 2 2 2 Transcription factor AFT DBD_Tnp_Mut PF03108.15 KND96630.1 - 0.0015 18.5 0.3 0.0023 17.9 0.3 1.3 1 0 0 1 1 1 1 MuDR family transposase HD_assoc PF13286.6 KND96630.1 - 0.19 12.3 0.0 0.4 11.2 0.0 1.5 1 0 0 1 1 1 0 Phosphohydrolase-associated domain Ribosomal_L12 PF00542.19 KND96631.1 - 5.8e-20 71.4 8.5 5.8e-20 71.4 8.5 2.3 3 0 0 3 3 3 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KND96631.1 - 2.7e-16 59.0 1.1 2.7e-16 59.0 1.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain Pkinase PF00069.25 KND96632.1 - 6.3e-72 242.1 0.0 8.4e-72 241.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND96632.1 - 1.5e-38 132.6 0.0 2.3e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND96632.1 - 3e-05 23.5 0.0 9.5e-05 21.8 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KND96632.1 - 0.076 11.9 1.9 0.13 11.2 1.9 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KND96632.1 - 0.17 10.9 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 TFIIA PF03153.13 KND96632.1 - 1.2 9.1 13.2 1.4 8.8 13.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nramp PF01566.18 KND96633.1 - 5e-82 275.7 17.7 8.4e-81 271.7 17.7 2.1 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein 60KD_IMP PF02096.20 KND96633.1 - 0.29 11.0 2.5 0.22 11.4 0.3 2.2 2 1 0 2 2 2 0 60Kd inner membrane protein DUF2964 PF11177.8 KND96633.1 - 3.1 8.1 11.0 0.56 10.5 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2964) Reticulon PF02453.17 KND96633.1 - 9 6.2 14.0 0.55 10.2 0.5 3.7 4 0 0 4 4 4 0 Reticulon Jas PF16135.5 KND96635.1 - 0.045 13.9 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 TPL-binding domain in jasmonate signalling zf-C2HE PF16278.5 KND96635.1 - 0.14 12.7 0.9 0.37 11.3 0.9 1.8 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 KND96635.1 - 0.77 10.1 6.1 0.28 11.5 1.9 2.3 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KND96635.1 - 2 9.5 13.7 0.69 10.9 0.8 4.3 4 1 0 4 4 4 0 C2H2-type zinc finger HAD PF12710.7 KND96636.1 - 5.5e-25 88.9 0.0 6.9e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KND96636.1 - 2.9e-05 23.6 0.0 4.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.26 KND96636.1 - 0.00025 21.4 0.0 0.0083 16.4 0.0 2.9 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KND96636.1 - 0.0029 17.2 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.6 KND96636.1 - 0.0055 16.8 0.0 0.48 10.5 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase SpoU_sub_bind PF08032.12 KND96636.1 - 0.011 16.0 0.0 0.56 10.5 0.0 2.6 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Pkinase PF00069.25 KND96637.1 - 3.1e-72 243.1 0.0 6.7e-72 242.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND96637.1 - 1.1e-34 120.0 0.0 3.7e-34 118.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND96637.1 - 0.00011 21.6 0.3 0.96 8.7 0.0 3.2 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 KND96637.1 - 0.0042 15.9 0.0 0.0077 15.0 0.0 1.6 1 1 0 1 1 1 1 Fungal protein kinase SNF2_N PF00176.23 KND96638.1 - 2.2e-37 128.6 0.4 1.2e-36 126.2 0.0 2.4 2 1 0 2 2 2 1 SNF2 family N-terminal domain zf-RING_2 PF13639.6 KND96638.1 - 2.4e-09 37.3 9.2 5.5e-09 36.2 9.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KND96638.1 - 3e-09 36.6 6.9 7e-09 35.4 6.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KND96638.1 - 1.1e-08 34.8 9.6 2.3e-08 33.8 9.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KND96638.1 - 2.4e-08 33.7 8.7 5.3e-08 32.6 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KND96638.1 - 2.3e-07 31.0 6.0 6e-07 29.7 6.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KND96638.1 - 7.3e-07 28.9 7.3 1.5e-06 27.9 7.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KND96638.1 - 0.00011 22.1 8.0 0.00024 21.0 8.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Helicase_C PF00271.31 KND96638.1 - 0.00031 21.1 0.0 0.0011 19.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 KND96638.1 - 0.0016 18.4 9.2 0.0039 17.2 9.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 KND96638.1 - 0.017 15.2 7.7 0.089 12.9 5.9 2.7 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 KND96638.1 - 0.13 12.3 1.8 0.3 11.2 1.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KND96638.1 - 0.19 11.5 7.2 0.088 12.6 3.9 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KND96638.1 - 0.53 10.5 8.7 1.5 9.1 8.7 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING tRNA_anti-codon PF01336.25 KND96639.1 - 1.7e-08 34.3 1.5 2.8e-08 33.6 0.2 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain RPA_C PF08784.11 KND96639.1 - 7.9e-07 29.7 0.2 2e-06 28.4 0.0 1.8 2 1 0 2 2 2 1 Replication protein A C terminal RMI2 PF16100.5 KND96639.1 - 0.0031 17.3 0.0 0.0067 16.3 0.0 1.5 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 Rrf2 PF02082.20 KND96639.1 - 0.16 12.3 0.0 18 5.8 0.0 2.7 3 0 0 3 3 3 0 Transcriptional regulator MFS_1 PF07690.16 KND96640.1 - 1.5e-36 126.1 35.4 1.5e-36 126.1 35.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND96640.1 - 2.6e-12 46.4 10.9 2.6e-12 46.4 10.9 2.4 2 2 1 3 3 3 1 Sugar (and other) transporter Csm1 PF12539.8 KND96642.1 - 2.1e-22 79.5 0.3 3.9e-22 78.7 0.3 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 SPICE PF15678.5 KND96642.1 - 0.81 9.0 11.0 0.1 11.9 1.6 2.3 2 0 0 2 2 2 0 Centriole duplication and mitotic chromosome congression zf-LYAR PF08790.11 KND96643.1 - 9e-16 57.5 5.6 9e-16 57.5 5.6 1.9 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 KND96643.1 - 0.0069 16.0 0.6 2.7 7.7 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-TRAF PF02176.18 KND96643.1 - 0.011 16.4 2.3 0.02 15.6 2.3 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger DM PF00751.18 KND96643.1 - 0.11 12.4 2.1 0.2 11.6 2.1 1.4 1 0 0 1 1 1 0 DM DNA binding domain RNHCP PF12647.7 KND96643.1 - 0.25 11.4 6.7 0.36 10.8 0.8 2.6 1 1 1 2 2 2 0 RNHCP domain zf-C2H2_4 PF13894.6 KND96643.1 - 1.4 9.9 5.6 12 7.0 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger COX16 PF14138.6 KND96645.1 - 1e-24 86.8 0.5 1.7e-24 86.1 0.5 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Arc_PepC_II PF06847.11 KND96645.1 - 0.15 12.6 0.5 1.2 9.7 0.0 2.1 1 1 1 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II WD40 PF00400.32 KND96646.1 - 2.7e-55 183.1 18.8 2.1e-10 41.0 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 KND96646.1 - 8.4e-30 102.9 10.9 1.6e-29 102.0 10.9 1.5 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 KND96646.1 - 5.5e-18 65.0 0.2 0.00022 21.5 0.0 5.6 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KND96646.1 - 1.5e-07 30.5 2.8 0.28 9.8 0.0 4.1 2 1 2 4 4 4 4 Nucleoporin Nup120/160 WD40_like PF17005.5 KND96646.1 - 7.8e-07 28.7 0.1 0.19 11.1 0.0 5.4 3 2 2 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 KND96646.1 - 0.00015 20.9 0.1 2.5 7.0 0.0 4.2 2 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein SUIM_assoc PF16619.5 KND96646.1 - 0.00088 19.3 0.4 0.00088 19.3 0.4 3.8 2 1 2 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 Ret2_MD PF18528.1 KND96646.1 - 0.043 14.2 0.0 8.1 6.9 0.0 3.3 1 1 2 3 3 3 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Frtz PF11768.8 KND96646.1 - 0.06 11.6 0.0 6.8 4.9 0.0 2.7 2 2 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 KND96646.1 - 0.11 12.5 0.0 30 4.7 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF1664 PF07889.12 KND96646.1 - 0.27 11.3 2.9 0.52 10.4 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) MDD_C PF18376.1 KND96648.1 - 2.6e-68 229.4 0.0 3.2e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain Enterotoxin_a PF01375.17 KND96648.1 - 0.077 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Heat-labile enterotoxin alpha chain CDP-OH_P_transf PF01066.21 KND96650.1 - 9.9e-12 45.5 0.1 9.9e-12 45.5 0.1 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase EF-G-binding_N PF07299.11 KND96651.1 - 0.3 11.7 1.6 9.7 6.8 0.1 2.9 2 1 1 3 3 3 0 Elongation factor G-binding protein, N-terminal Pex24p PF06398.11 KND96652.1 - 0.092 11.7 3.5 0.12 11.4 3.5 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin bZIP_1 PF00170.21 KND96654.1 - 8.3e-11 41.8 14.0 1.4e-10 41.1 14.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KND96654.1 - 0.00072 19.6 13.6 0.0015 18.5 13.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KND96654.1 - 0.0061 17.1 7.9 0.0061 17.1 7.9 2.0 2 0 0 2 2 2 1 bZIP Maf transcription factor DUF4337 PF14235.6 KND96654.1 - 0.77 9.9 3.5 1.2 9.2 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Cpn60_TCP1 PF00118.24 KND96655.1 - 2.9e-148 494.6 7.1 3.2e-148 494.4 7.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PRAI PF00697.22 KND96656.1 - 6.1e-42 143.6 0.0 3.2e-36 124.9 0.0 2.1 1 1 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Vps53_N PF04100.12 KND96657.1 - 3.7e-66 223.6 19.0 3.7e-66 223.6 19.0 2.2 2 1 0 2 2 2 1 Vps53-like, N-terminal PMC2NT PF08066.12 KND96657.1 - 0.25 12.0 1.9 0.82 10.4 0.3 2.9 2 0 0 2 2 2 0 PMC2NT (NUC016) domain CLZ PF16526.5 KND96657.1 - 6.9 7.1 6.1 8.4 6.8 0.0 3.5 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Kelch_5 PF13854.6 KND96658.1 - 1.5e-32 111.0 15.2 2.2e-08 33.9 0.1 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KND96658.1 - 5.1e-30 103.2 7.5 8.3e-07 28.9 0.2 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 KND96658.1 - 2.8e-25 88.1 3.5 4.6e-06 26.8 0.2 5.7 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KND96658.1 - 7.5e-23 80.0 3.1 1.1e-08 35.0 0.1 6.3 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KND96658.1 - 1.3e-20 72.7 3.8 2e-10 40.0 0.1 6.1 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 KND96658.1 - 8.5e-16 57.2 3.9 2.6e-08 33.5 0.3 6.0 6 0 0 6 6 6 2 Kelch motif GAS PF13851.6 KND96658.1 - 0.011 15.1 1.7 0.011 15.1 1.7 4.2 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding RAG2 PF03089.14 KND96658.1 - 0.093 11.7 0.1 3.4 6.6 0.0 2.8 3 0 0 3 3 3 0 Recombination activating protein 2 Baculo_PEP_C PF04513.12 KND96658.1 - 0.15 12.1 16.5 0.57 10.2 0.1 3.7 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 KND96658.1 - 0.42 10.8 27.4 0.18 12.0 0.4 4.7 4 1 1 5 5 5 0 Fibrinogen alpha/beta chain family Golgin_A5 PF09787.9 KND96658.1 - 0.9 8.9 38.8 0.015 14.8 3.3 4.3 2 1 1 4 4 4 0 Golgin subfamily A member 5 Phage_GP20 PF06810.11 KND96658.1 - 1.6 8.5 38.8 0.1 12.4 1.8 4.2 4 0 0 4 4 4 0 Phage minor structural protein GP20 HMMR_N PF15905.5 KND96658.1 - 2.6 7.4 44.8 2.6 7.4 0.6 4.3 3 1 0 3 3 3 0 Hyaluronan mediated motility receptor N-terminal PKcGMP_CC PF16808.5 KND96658.1 - 4.3 7.3 6.5 1.2 9.1 0.1 3.2 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Arrestin_N PF00339.29 KND96660.1 - 1.4e-14 54.4 0.0 2.9e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KND96660.1 - 1.5e-10 41.7 0.0 9.4e-09 35.8 0.0 2.9 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain LIN37 PF15306.6 KND96662.1 - 0.23 11.7 3.9 0.27 11.5 3.9 1.0 1 0 0 1 1 1 0 LIN37 RRM_1 PF00076.22 KND96663.1 - 5.2e-42 141.5 0.0 1.3e-19 69.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KND96663.1 - 0.035 13.7 0.0 0.15 11.7 0.0 2.0 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KND96663.1 - 0.09 12.8 0.0 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif HMGL-like PF00682.19 KND96665.1 - 3.8e-84 282.4 0.0 5.4e-84 281.8 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KND96665.1 - 8.5e-28 96.9 0.1 1.5e-27 96.1 0.1 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Ribosomal_L13 PF00572.18 KND96666.1 - 7.5e-12 45.6 0.7 6.3e-10 39.4 0.1 2.6 2 1 0 2 2 2 1 Ribosomal protein L13 Aldedh PF00171.22 KND96668.1 - 6.9e-113 377.6 0.0 8.3e-113 377.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF676 PF05057.14 KND96669.1 - 3.7e-08 33.1 0.0 3.3e-07 30.1 0.0 2.2 1 1 1 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KND96669.1 - 4.1e-06 26.7 0.0 1.3e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein Palm_thioest PF02089.15 KND96669.1 - 3e-05 24.0 0.0 4.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 KND96669.1 - 5.5e-05 22.6 0.0 0.001 18.4 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.20 KND96669.1 - 0.00017 21.3 0.0 0.00044 20.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.15 KND96669.1 - 0.00084 18.6 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.25 KND96669.1 - 0.0035 17.2 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KND96669.1 - 0.028 13.7 0.0 0.049 12.9 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KND96669.1 - 0.079 13.6 0.0 0.1 13.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_2 PF01674.18 KND96669.1 - 0.15 11.5 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 2) FAD_binding_3 PF01494.19 KND96670.1 - 4.3e-21 75.6 0.1 6.6e-19 68.4 0.1 2.4 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 KND96670.1 - 6e-05 22.2 0.0 9.4e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 KND96670.1 - 0.00019 20.6 0.3 0.0091 15.1 0.1 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KND96670.1 - 0.0002 20.7 0.0 0.00066 19.0 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KND96670.1 - 0.00022 21.2 0.0 0.003 17.6 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KND96670.1 - 0.016 14.1 0.0 1.4 7.6 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase DAO PF01266.24 KND96670.1 - 0.027 14.1 0.1 0.085 12.4 0.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KND96670.1 - 0.11 11.7 0.1 0.57 9.4 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KND96670.1 - 0.14 11.3 0.0 0.33 10.2 0.0 1.5 1 0 0 1 1 1 0 Thi4 family NAP PF00956.18 KND96671.1 - 1.3e-16 60.6 2.2 2.3e-16 59.8 2.2 1.4 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) zinc_ribbon_11 PF11682.8 KND96671.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Probable zinc-ribbon RNA_pol_I_A49 PF06870.12 KND96672.1 - 1.3e-108 363.3 0.2 1.5e-108 363.1 0.2 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DMAP1 PF05499.12 KND96672.1 - 0.00039 20.3 0.3 0.00086 19.2 0.2 1.6 2 0 0 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) DnaJ PF00226.31 KND96673.1 - 3.1e-15 56.1 0.9 4.5e-15 55.5 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 KND96673.1 - 8.9e-15 54.2 0.0 1.5e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 CSL zinc finger Lar_restr_allev PF14354.6 KND96673.1 - 0.013 15.9 0.3 0.022 15.1 0.3 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar LCAT PF02450.15 KND96675.1 - 4.3e-06 26.1 0.0 7.4e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 KND96675.1 - 4.2e-05 22.9 0.0 7.2e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KND96675.1 - 0.00057 20.6 0.0 0.0011 19.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 KND96675.1 - 0.0048 16.4 0.0 0.0077 15.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 KND96675.1 - 0.059 13.0 0.0 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KND96675.1 - 0.18 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_M41 PF01434.18 KND96677.1 - 1.1e-68 230.8 0.0 2.8e-68 229.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 KND96677.1 - 2.3e-42 144.5 0.0 5.2e-42 143.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KND96677.1 - 2.7e-13 49.5 0.2 1.3e-12 47.3 0.2 2.2 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KND96677.1 - 1.5e-06 28.5 0.0 5.2e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 FtsH Extracellular TIP49 PF06068.13 KND96677.1 - 0.0016 17.7 0.1 0.0078 15.5 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 KND96677.1 - 0.014 15.4 0.3 0.058 13.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KND96677.1 - 0.018 14.8 0.0 0.044 13.5 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KND96677.1 - 0.019 15.4 0.6 0.09 13.2 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.6 KND96677.1 - 0.02 15.3 0.0 0.068 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KND96677.1 - 0.026 14.6 0.4 0.15 12.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KND96677.1 - 0.029 14.1 0.0 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_22 PF13401.6 KND96677.1 - 0.082 13.2 0.1 2.2 8.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KND96677.1 - 0.094 13.3 0.7 0.82 10.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain Ovate PF04844.13 KND96677.1 - 0.2 11.7 1.0 2.4 8.2 0.2 2.8 2 0 0 2 2 2 0 Transcriptional repressor, ovate CRC_subunit PF08624.10 KND96679.1 - 1.6e-47 161.3 0.2 2.4e-47 160.7 0.2 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Bro-N PF02498.17 KND96679.1 - 0.037 14.7 0.0 0.14 12.9 0.0 2.0 1 0 0 1 1 1 0 BRO family, N-terminal domain YL1 PF05764.13 KND96679.1 - 0.54 10.3 23.8 1.1 9.3 23.8 1.5 1 0 0 1 1 1 0 YL1 nuclear protein NAM-associated PF14303.6 KND96679.1 - 1.4 9.6 8.3 3.3 8.4 8.3 1.6 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SDA1 PF05285.12 KND96679.1 - 1.7 8.0 26.7 2.7 7.3 26.7 1.4 1 0 0 1 1 1 0 SDA1 LZ_Tnp_IS66 PF13007.7 KND96679.1 - 4.4 8.2 9.0 16 6.4 4.3 2.7 1 1 1 2 2 2 0 Transposase C of IS166 homeodomain CDC45 PF02724.14 KND96679.1 - 5.5 5.2 17.2 8.1 4.6 17.2 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2 PF00096.26 KND96680.1 - 2e-05 24.8 4.6 0.076 13.5 0.1 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 KND96680.1 - 0.02 15.2 1.0 0.073 13.4 1.1 1.9 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf_ZIC PF18366.1 KND96680.1 - 0.22 11.6 0.9 0.43 10.7 0.1 1.9 2 0 0 2 2 2 0 Zic proteins zinc finger domain RPAP1_N PF08621.10 KND96681.1 - 0.014 15.1 3.7 0.29 10.9 1.2 2.8 2 0 0 2 2 2 0 RPAP1-like, N-terminal DUF4085 PF13315.6 KND96681.1 - 0.12 12.0 1.0 0.21 11.2 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) Abhydrolase_1 PF00561.20 KND96683.1 - 2e-26 93.2 0.1 2.7e-26 92.8 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KND96683.1 - 5.1e-18 64.4 0.0 9.7e-18 63.5 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KND96683.1 - 1.2e-05 24.8 0.0 0.00012 21.5 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KND96683.1 - 0.00085 19.2 0.0 0.18 11.6 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DUF2974 PF11187.8 KND96683.1 - 0.063 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Sod_Cu PF00080.20 KND96686.1 - 6.8e-17 62.0 0.2 9.7e-17 61.5 0.2 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) OPT PF03169.15 KND96688.1 - 5e-152 507.7 40.5 5.7e-152 507.5 40.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein YtzH PF14165.6 KND96688.1 - 0.047 14.1 0.1 0.1 13.0 0.1 1.5 1 0 0 1 1 1 0 YtzH-like protein Amidase PF01425.21 KND96689.1 - 2.3e-89 300.5 0.0 2.9e-89 300.1 0.0 1.1 1 0 0 1 1 1 1 Amidase Endonuclease_NS PF01223.23 KND96691.1 - 7.9e-65 218.8 0.0 9.2e-65 218.6 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease DUF1729 PF08354.10 KND96692.1 - 1.3e-159 530.9 0.0 1.9e-159 530.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KND96692.1 - 3.9e-94 315.7 0.0 1.9e-92 310.2 0.0 2.9 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 KND96692.1 - 3.4e-45 153.4 0.0 7.1e-45 152.4 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 KND96692.1 - 3.2e-41 141.7 0.0 5.7e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 KND96692.1 - 2.7e-39 133.6 0.0 5.4e-39 132.6 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain FAS_N PF17828.1 KND96692.1 - 2.7e-28 98.5 0.1 9.4e-28 96.8 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 KND96692.1 - 1.6e-16 60.7 0.0 4.8e-16 59.1 0.0 1.9 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase DUF438 PF04282.13 KND96692.1 - 0.068 13.1 0.7 0.49 10.4 0.4 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF438) His_Phos_2 PF00328.22 KND96693.1 - 5.9e-136 453.8 0.2 1.1e-135 452.9 0.1 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KND96693.1 - 1.1e-36 124.9 0.0 3.7e-36 123.1 0.0 2.0 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KND96693.1 - 9.1e-06 25.4 0.0 1.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain FAM183 PF14886.6 KND96693.1 - 1 10.1 3.7 31 5.3 0.2 3.4 3 0 0 3 3 3 0 FAM183A and FAM183B related Pribosyl_synth PF14572.6 KND96695.1 - 6.4e-40 137.1 1.7 3.4e-38 131.5 1.7 2.1 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KND96695.1 - 3.8e-07 29.8 0.3 3.8e-06 26.5 0.3 2.1 1 1 0 1 1 1 1 Phosphoribosyl transferase domain SRR1 PF07985.12 KND96696.1 - 1.8e-18 66.3 0.4 4.3e-18 65.1 0.4 1.7 1 0 0 1 1 1 1 SRR1 HSF_DNA-bind PF00447.17 KND96697.1 - 5.9e-30 103.7 5.5 1.1e-29 102.8 5.5 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 KND96697.1 - 3.7e-27 94.7 1.2 1.3e-26 93.0 0.8 2.0 2 0 0 2 2 2 1 Response regulator receiver domain Spermine_synth PF01564.17 KND96697.1 - 0.0062 16.0 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Nmad5 PF18757.1 KND96697.1 - 0.0092 16.2 0.7 0.022 15.0 0.7 1.6 1 0 0 1 1 1 1 Nucleotide modification associated domain 5 ZapB PF06005.12 KND96697.1 - 0.02 15.3 0.4 0.051 14.0 0.4 1.7 1 0 0 1 1 1 0 Cell division protein ZapB Ets PF00178.22 KND96697.1 - 0.12 12.8 0.3 0.26 11.8 0.3 1.6 1 0 0 1 1 1 0 Ets-domain GIY-YIG PF01541.24 KND96699.1 - 4e-12 46.2 0.0 1.4e-11 44.5 0.0 1.8 2 0 0 2 2 2 1 GIY-YIG catalytic domain C1_2 PF03107.16 KND96699.1 - 0.001 19.3 2.6 0.001 19.3 2.6 1.9 2 0 0 2 2 2 1 C1 domain zf-rbx1 PF12678.7 KND96699.1 - 0.055 13.8 6.9 0.12 12.7 5.2 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-HC5HC2H PF13771.6 KND96699.1 - 0.15 12.3 3.7 0.36 11.1 3.6 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-ANAPC11 PF12861.7 KND96699.1 - 0.26 11.3 8.9 0.14 12.2 5.6 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KND96699.1 - 0.42 11.0 12.1 1.4 9.3 9.7 2.4 2 0 0 2 2 2 0 Ring finger domain zf-HC5HC2H_2 PF13832.6 KND96699.1 - 1.7 8.8 7.8 3.4 7.9 5.2 2.4 2 1 0 2 2 2 0 PHD-zinc-finger like domain zf-RING_4 PF14570.6 KND96699.1 - 8.2 6.3 11.3 0.87 9.4 6.2 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Glyco_hydro_31 PF01055.26 KND96700.1 - 4.2e-126 421.7 4.9 5.9e-126 421.2 4.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KND96700.1 - 6.5e-22 77.6 0.4 6.5e-22 77.6 0.4 3.2 4 0 0 4 4 4 1 Galactose mutarotase-like DUF5110 PF17137.4 KND96700.1 - 0.0019 18.5 0.0 0.0061 16.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) BRE1 PF08647.11 KND96702.1 - 2.9e-22 78.5 13.1 2.9e-22 78.5 13.1 6.8 5 2 1 6 6 5 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.6 KND96702.1 - 5.4e-09 35.7 6.8 1e-08 34.9 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KND96702.1 - 6.2e-09 35.6 6.1 1e-08 34.9 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KND96702.1 - 8e-08 32.0 5.3 1.5e-07 31.2 5.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KND96702.1 - 1.1e-07 31.7 8.0 2e-07 30.8 8.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KND96702.1 - 4.4e-07 29.7 6.5 8.6e-07 28.7 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KND96702.1 - 1.2e-06 28.7 7.5 2.1e-06 27.9 7.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KND96702.1 - 3.9e-05 23.6 5.6 9.2e-05 22.4 5.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KND96702.1 - 0.0068 16.5 4.8 0.018 15.2 4.8 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING APG6_N PF17675.1 KND96702.1 - 0.0086 16.6 9.1 0.0086 16.6 9.1 7.8 1 1 5 6 6 4 1 Apg6 coiled-coil region zf-rbx1 PF12678.7 KND96702.1 - 0.018 15.3 4.9 0.044 14.1 4.9 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF3755 PF12579.8 KND96702.1 - 0.021 14.4 1.4 0.057 13.1 1.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3755) zf-C2H2 PF00096.26 KND96702.1 - 0.052 14.0 0.2 0.052 14.0 0.2 2.2 2 0 0 2 2 1 0 Zinc finger, C2H2 type zf-RING_10 PF16685.5 KND96702.1 - 0.13 12.5 3.9 0.37 11.0 3.9 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C2H2_4 PF13894.6 KND96702.1 - 0.14 13.1 1.9 0.68 10.9 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KND96702.1 - 0.21 11.6 2.3 2.4 8.2 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-RING_6 PF14835.6 KND96702.1 - 0.32 10.9 2.9 0.68 9.8 2.9 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-met PF12874.7 KND96702.1 - 0.52 10.8 2.2 0.57 10.7 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF1272 PF06906.11 KND96702.1 - 0.6 10.2 4.4 1.3 9.2 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_4 PF14570.6 KND96702.1 - 2.6 7.9 5.8 5.5 6.9 5.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain HypA PF01155.19 KND96702.1 - 6.1 6.9 8.2 34 4.5 8.0 2.5 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Bromodomain PF00439.25 KND96703.1 - 8.8e-41 137.9 1.0 1.8e-21 76.0 0.1 2.7 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KND96703.1 - 5.4e-14 52.1 2.8 1.5e-13 50.7 2.8 1.8 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF1013 PF06242.11 KND96703.1 - 0.018 15.1 4.3 0.079 13.0 2.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1013) VPS38 PF17649.1 KND96703.1 - 0.08 11.8 6.4 0.13 11.1 6.4 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting 38 DUF4441 PF14536.6 KND96703.1 - 0.2 11.9 0.1 0.2 11.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) Dus PF01207.17 KND96704.1 - 1.9e-77 260.4 0.0 2.6e-77 260.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 KND96704.1 - 0.00058 19.2 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase Resolvase PF00239.21 KND96704.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 Resolvase, N terminal domain His_biosynth PF00977.21 KND96704.1 - 0.015 14.8 0.1 0.21 11.0 0.1 2.2 1 1 2 3 3 3 0 Histidine biosynthesis protein MTHFR PF02219.17 KND96704.1 - 0.019 14.3 0.1 3.7 6.8 0.0 2.4 1 1 1 2 2 2 0 Methylenetetrahydrofolate reductase DHO_dh PF01180.21 KND96704.1 - 0.029 13.6 0.0 0.051 12.8 0.0 1.3 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase BtpA PF03437.15 KND96704.1 - 0.061 12.8 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 BtpA family Oxidored_FMN PF00724.20 KND96704.1 - 0.077 12.3 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family MR_MLE_C PF13378.6 KND96704.1 - 0.093 12.3 0.0 1.1 8.8 0.0 2.3 1 1 0 1 1 1 0 Enolase C-terminal domain-like NMO PF03060.15 KND96704.1 - 0.14 11.5 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase SMC_N PF02463.19 KND96705.1 - 3.8e-62 209.6 58.3 3.9e-37 127.8 0.0 3.6 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KND96705.1 - 1.6e-21 76.8 0.0 5.9e-21 75.0 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KND96705.1 - 5.9e-11 42.7 13.1 6.1e-05 23.0 0.8 3.9 3 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KND96705.1 - 0.00021 21.0 0.0 0.00051 19.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF812 PF05667.11 KND96705.1 - 0.0028 16.6 26.6 0.0028 16.6 26.6 5.4 2 2 2 5 5 5 1 Protein of unknown function (DUF812) TolA_bind_tri PF16331.5 KND96705.1 - 0.7 10.0 0.0 0.7 10.0 0.0 8.1 7 1 1 8 8 8 0 TolA binding protein trimerisation DUF1664 PF07889.12 KND96705.1 - 4.6 7.3 88.6 0.069 13.2 9.3 8.3 5 2 2 9 9 9 0 Protein of unknown function (DUF1664) RNA_polI_A14 PF08203.11 KND96706.1 - 6.8e-20 71.6 0.0 6.8e-20 71.6 0.0 2.7 2 1 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 CDC45 PF02724.14 KND96706.1 - 0.021 13.2 18.8 0.021 13.2 18.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4604 PF15377.6 KND96706.1 - 0.03 14.7 32.9 0.043 14.2 32.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) GAGA_bind PF06217.12 KND96706.1 - 1.4 9.1 14.3 1.9 8.7 14.3 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family V_ATPase_I PF01496.19 KND96706.1 - 6.4 4.6 13.3 6.9 4.4 13.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DnaJ_C PF01556.18 KND96709.1 - 7.6e-33 113.7 0.1 1.1e-32 113.1 0.1 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KND96709.1 - 3.9e-24 84.5 3.1 6.6e-24 83.8 3.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KND96709.1 - 3.3e-12 46.6 16.9 8.2e-12 45.3 16.9 1.7 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KND96709.1 - 0.00069 19.5 7.7 0.0054 16.7 0.4 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KND96709.1 - 0.039 14.0 4.8 1.6 8.8 0.2 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KND96709.1 - 0.56 10.3 8.7 1.9 8.5 0.7 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-C2H2 PF00096.26 KND96713.1 - 5.3e-09 36.0 7.6 0.00049 20.4 1.2 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KND96713.1 - 3e-06 27.4 7.2 0.016 15.6 0.1 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KND96713.1 - 1.3e-05 25.7 6.9 0.02 15.7 1.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KND96713.1 - 0.0002 21.6 1.0 0.0028 18.0 0.2 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KND96713.1 - 0.016 15.5 1.7 0.082 13.2 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KND96713.1 - 0.13 12.2 4.9 1.1 9.2 0.3 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PIR PF00399.19 KND96721.1 - 3.6e-13 48.7 74.4 5.9e-06 25.7 8.0 6.6 6 0 0 6 6 6 6 Yeast PIR protein repeat TFIIA PF03153.13 KND96721.1 - 0.82 9.6 13.2 0.98 9.3 13.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 KND96722.1 - 2.5e-73 246.7 0.2 3.7e-73 246.1 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND96722.1 - 1.7e-31 109.4 0.1 1.3e-21 77.1 0.3 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KND96722.1 - 2.6e-08 33.5 0.6 0.00018 20.9 0.0 2.9 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KND96722.1 - 0.0033 16.3 0.6 0.0066 15.3 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KND96722.1 - 0.049 13.0 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_14 PF13428.6 KND96725.1 - 2.6e-05 24.7 11.1 0.36 11.8 1.3 7.0 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 KND96725.1 - 0.00046 20.4 0.5 1.1 9.7 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Suf PF05843.14 KND96725.1 - 0.0016 18.5 11.0 2.8 7.8 0.1 5.3 3 1 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_8 PF13181.6 KND96725.1 - 0.0042 17.2 10.6 0.25 11.7 0.3 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KND96725.1 - 0.0049 16.8 0.9 28 5.0 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KND96725.1 - 0.21 11.9 4.5 3 8.2 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.6 KND96725.1 - 0.32 10.4 5.6 2.4 7.5 0.1 3.1 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 KND96725.1 - 0.49 10.6 10.8 7.3 7.0 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KND96725.1 - 0.64 10.3 3.8 0.64 10.3 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KND96725.1 - 0.97 9.2 7.3 16 5.3 0.1 4.3 5 0 0 5 5 5 0 TPR repeat TPR_1 PF00515.28 KND96725.1 - 1.6 8.7 6.2 75 3.4 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat SBE2 PF17076.5 KND96726.1 - 8.5e-10 37.5 12.8 1.3e-09 36.9 12.8 1.3 1 0 0 1 1 1 1 SBE2, cell-wall formation zf-GRF PF06839.12 KND96727.1 - 0.14 12.2 2.5 6 7.0 0.1 2.3 2 0 0 2 2 2 0 GRF zinc finger Cullin PF00888.22 KND96728.1 - 6.1e-139 464.5 11.4 9.1e-139 463.9 11.4 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KND96728.1 - 9.1e-25 86.5 0.8 9.1e-25 86.5 0.8 2.7 3 0 0 3 3 3 1 Cullin protein neddylation domain ASPRs PF17641.2 KND96728.1 - 0.12 12.7 0.5 0.38 11.0 0.0 2.2 2 0 0 2 2 2 0 Ancylostoma-associated secreted protein related SUIM_assoc PF16619.5 KND96728.1 - 0.12 12.4 3.8 0.14 12.2 1.1 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 NifQ PF04891.12 KND96728.1 - 0.29 11.5 1.4 0.93 9.8 0.1 2.3 2 0 0 2 2 2 0 NifQ DUF4252 PF14060.6 KND96729.1 - 0.027 14.4 0.2 0.027 14.4 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) Aconitase PF00330.20 KND96730.1 - 1.5e-160 535.2 0.1 1.9e-160 534.9 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KND96730.1 - 3.2e-43 147.2 0.0 6.2e-43 146.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Pex14_N PF04695.13 KND96733.1 - 0.066 13.9 0.6 0.066 13.9 0.6 5.6 1 1 2 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1682 PF07946.14 KND96733.1 - 6 6.0 18.0 11 5.1 18.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) OCD_Mu_crystall PF02423.15 KND96734.1 - 6.5e-19 68.0 0.0 7.7e-19 67.8 0.0 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KND96734.1 - 8.9e-07 29.0 0.0 1.8e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KND96734.1 - 0.003 18.1 0.1 0.01 16.4 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Alk_phosphatase PF00245.20 KND96737.1 - 1.2e-112 376.9 0.0 1.5e-112 376.6 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KND96737.1 - 2.4e-05 23.8 0.0 6.2e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Metalloenzyme superfamily MFS_1 PF07690.16 KND96738.1 - 5.7e-34 117.6 25.2 5.7e-34 117.6 25.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND96738.1 - 9.3e-10 37.9 22.1 1.4e-09 37.3 22.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KND96738.1 - 3.1e-05 23.5 1.5 3.1e-05 23.5 1.5 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Wzz PF02706.15 KND96738.1 - 2.4 8.5 4.6 3.9 7.8 1.3 2.8 2 1 0 2 2 2 0 Chain length determinant protein Beta_elim_lyase PF01212.21 KND96739.1 - 4.8e-78 262.4 0.0 6.7e-78 261.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KND96739.1 - 2.7e-06 26.8 0.0 4.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KND96739.1 - 0.041 13.2 0.0 0.16 11.2 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KND96739.1 - 0.091 11.7 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V CooT PF10133.9 KND96739.1 - 0.14 12.5 0.0 0.53 10.6 0.0 2.0 1 0 0 1 1 1 0 CO dehydrogenase accessory protein CooT Golgin_A5 PF09787.9 KND96740.1 - 0.021 14.3 19.1 0.13 11.7 19.1 1.9 1 1 0 1 1 1 0 Golgin subfamily A member 5 Spc7 PF08317.11 KND96740.1 - 0.063 12.1 16.5 0.082 11.8 15.8 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 KND96740.1 - 1.9 9.1 14.4 0.88 10.2 0.8 2.8 1 1 1 2 2 2 0 Initiation control protein YabA ATG16 PF08614.11 KND96740.1 - 3.2 8.0 17.5 5.9 7.1 17.5 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KND96740.1 - 5.7 7.5 22.4 2.8 8.5 2.0 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region MFS_1 PF07690.16 KND96741.1 - 1e-13 51.0 6.5 1e-13 51.0 6.5 2.8 3 0 0 3 3 3 2 Major Facilitator Superfamily TMEM132D_C PF15706.5 KND96741.1 - 0.085 12.6 0.0 0.085 12.6 0.0 2.9 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term RabGAP-TBC PF00566.18 KND96742.1 - 0.0025 17.5 8.2 0.035 13.8 0.0 3.4 3 1 1 4 4 4 3 Rab-GTPase-TBC domain ubiquitin PF00240.23 KND96748.1 - 4.6e-168 545.3 27.6 4.7e-33 112.7 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 KND96748.1 - 4.3e-79 260.4 28.3 2.9e-15 55.9 0.7 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KND96748.1 - 8.3e-28 96.7 14.8 0.00061 20.2 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 KND96748.1 - 5.4e-20 71.1 5.5 0.038 13.9 0.0 5.2 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KND96748.1 - 3.3e-18 65.8 12.2 0.04 14.3 0.1 5.1 5 0 0 5 5 5 5 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KND96748.1 - 2.2e-17 63.2 4.7 0.18 12.0 0.0 6.0 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KND96748.1 - 7e-16 58.7 2.8 0.49 11.0 0.0 5.2 1 1 3 5 5 5 5 DUF2407 ubiquitin-like domain Methyltrans_RNA PF04452.14 KND96748.1 - 3.1e-08 33.3 1.3 2.6 7.3 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase Ubiquitin_4 PF18036.1 KND96748.1 - 9.8e-08 31.9 32.0 22 5.2 0.2 9.9 10 0 0 10 10 10 0 Ubiquitin-like domain DUF2870 PF11069.8 KND96748.1 - 2.4e-07 31.0 0.0 40 4.7 0.0 5.6 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) DUF3861 PF12977.7 KND96748.1 - 5.3e-07 29.7 5.3 18 5.6 0.0 5.2 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 KND96748.1 - 1.6e-06 27.8 7.7 13 5.7 0.0 5.3 5 0 0 5 5 5 0 ACT domain Big_7 PF17957.1 KND96748.1 - 2.4e-06 28.2 0.6 71 4.3 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 KND96748.1 - 1.4e-05 25.2 7.4 9.9 6.3 0.0 4.9 5 0 0 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 KND96748.1 - 3e-05 23.6 0.0 32 3.8 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF969) DUF493 PF04359.14 KND96748.1 - 0.00037 21.0 0.1 1.9e+02 2.7 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF493) YcgR_2 PF12945.7 KND96748.1 - 0.00041 20.5 9.7 38 4.5 0.1 5.2 5 0 0 5 5 5 0 Flagellar protein YcgR ORF11CD3 PF10549.9 KND96748.1 - 0.00068 19.7 0.0 1.2e+02 2.9 0.0 5.1 5 0 0 5 5 5 0 ORF11CD3 domain ACT_4 PF13291.6 KND96748.1 - 0.0018 18.8 2.5 1.9e+02 2.7 0.0 5.1 5 0 0 5 5 5 0 ACT domain Baculo_p48 PF04878.13 KND96748.1 - 0.024 13.6 0.0 84 1.9 0.0 3.8 4 0 0 4 4 4 0 Baculovirus P48 protein ProRS-C_2 PF09181.10 KND96748.1 - 0.14 12.3 9.2 1.4e+02 2.7 0.1 5.0 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 KND96748.1 - 0.19 11.9 36.0 8 6.8 1.4 5.3 5 0 0 5 5 5 0 Tash protein PEST motif HAMP_N3 PF18575.1 KND96748.1 - 0.23 11.1 3.3 2.6e+02 1.3 0.0 4.7 5 0 0 5 5 5 0 HAMP N-terminal domain 3 Myosin_N PF02736.19 KND96748.1 - 0.28 11.0 9.4 1.4e+02 2.4 0.0 6.1 5 0 0 5 5 5 0 Myosin N-terminal SH3-like domain PI3K_p85B PF02192.16 KND96748.1 - 5.6 6.8 13.6 1.3e+02 2.5 0.1 5.1 5 0 0 5 5 5 0 PI3-kinase family, p85-binding domain Ecm29 PF13001.7 KND96749.1 - 5.3e-128 427.8 1.2 2.4e-127 425.6 1.2 2.3 1 0 0 1 1 1 1 Proteasome stabiliser HEAT PF02985.22 KND96749.1 - 3.5e-11 42.4 4.9 0.0059 16.8 0.0 8.9 9 0 0 9 9 9 2 HEAT repeat Vac14_Fab1_bd PF12755.7 KND96749.1 - 9.1e-11 42.2 0.3 0.00015 22.3 0.0 6.0 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KND96749.1 - 6.1e-06 26.6 4.6 2.3 8.8 0.0 7.0 5 0 0 5 5 5 1 HEAT-like repeat NOG1_N PF17835.1 KND96749.1 - 0.27 11.2 2.3 22 5.0 0.2 3.4 3 0 0 3 3 3 0 NOG1 N-terminal helical domain SecE PF00584.20 KND96750.1 - 0.0081 16.1 0.2 0.011 15.7 0.2 1.3 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex IF-2B PF01008.17 KND96751.1 - 7.2e-76 255.1 5.8 4e-39 134.5 0.0 2.4 3 0 0 3 3 3 2 Initiation factor 2 subunit family PhoLip_ATPase_C PF16212.5 KND96752.1 - 3.5e-82 275.9 23.0 3.5e-82 275.9 23.0 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KND96752.1 - 9.7e-23 79.7 9.3 9.7e-23 79.7 9.3 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KND96752.1 - 1.4e-12 47.6 0.0 1.1e-11 44.7 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KND96752.1 - 5e-12 46.6 0.4 8.5e-06 26.2 0.1 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KND96752.1 - 4.9e-05 22.9 0.4 0.00019 21.0 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KND96752.1 - 0.00067 19.5 0.8 0.013 15.2 0.0 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase ACR_tran PF00873.19 KND96752.1 - 0.12 10.1 0.0 0.18 9.4 0.0 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Mt_ATP-synt_B PF05405.14 KND96752.1 - 9.7 5.8 7.5 0.45 10.1 0.1 2.6 4 0 0 4 4 4 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) SMK-1 PF04802.15 KND96753.1 - 0.048 13.5 0.2 0.059 13.2 0.2 1.1 1 0 0 1 1 1 0 Component of IIS longevity pathway SMK-1 CCSAP PF15748.5 KND96755.1 - 1.8 8.6 31.3 3.5 7.7 7.4 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 KND96755.1 - 9.1 6.0 26.7 4.4 7.0 7.6 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Aldedh PF00171.22 KND96756.1 - 9.4e-20 70.5 1.9 3.9e-15 55.3 1.2 2.4 2 1 0 2 2 2 2 Aldehyde dehydrogenase family URO-D PF01208.17 KND96756.1 - 0.02 14.1 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) NPHI_C PF08469.10 KND96756.1 - 0.071 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Nucleoside triphosphatase I C-terminal NAD_binding_7 PF13241.6 KND96757.1 - 3.3e-30 104.6 0.0 5.7e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KND96757.1 - 2.6e-12 46.2 1.2 3.8e-12 45.7 0.1 1.8 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KND96757.1 - 2.2e-10 39.8 0.1 4.2e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central DUF2152 PF10222.9 KND96757.1 - 0.0069 14.8 1.1 0.01 14.2 0.3 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2152) Pyr_redox_3 PF13738.6 KND96757.1 - 0.043 13.1 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AbiJ_NTD4 PF18863.1 KND96757.1 - 0.061 13.8 0.1 0.1 13.0 0.1 1.6 1 1 0 1 1 1 0 AbiJ N-terminal domain 4 LSDAT_prok PF18171.1 KND96757.1 - 0.079 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Shikimate_DH PF01488.20 KND96757.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF2633 PF11119.8 KND96758.1 - 0.062 13.2 0.4 0.084 12.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) GDI PF00996.18 KND96759.1 - 1.2e-37 129.5 1.3 5.6e-37 127.3 0.2 2.3 2 1 0 2 2 2 1 GDP dissociation inhibitor FAD_binding_3 PF01494.19 KND96759.1 - 0.16 11.1 0.0 0.82 8.8 0.0 2.1 2 1 0 2 2 2 0 FAD binding domain Ribosomal_L7Ae PF01248.26 KND96760.1 - 3.9e-25 87.4 1.1 5.3e-25 87.0 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family KNOX2 PF03791.13 KND96760.1 - 0.021 14.3 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 KNOX2 domain NTP_transf_3 PF12804.7 KND96760.1 - 0.027 14.8 0.1 0.04 14.3 0.1 1.4 1 1 0 1 1 1 0 MobA-like NTP transferase domain SBD_N PF07005.11 KND96760.1 - 0.061 13.1 0.3 0.076 12.7 0.3 1.2 1 0 0 1 1 1 0 Sugar-binding N-terminal domain Gin PF10764.9 KND96760.1 - 0.11 12.5 1.0 0.18 11.8 1.0 1.3 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin Fez1 PF06818.15 KND96762.1 - 0.00069 20.1 3.0 0.0013 19.3 3.0 1.5 1 0 0 1 1 1 1 Fez1 DHR10 PF18595.1 KND96762.1 - 0.012 15.6 1.5 0.012 15.6 1.5 1.9 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain APG6_N PF17675.1 KND96762.1 - 0.023 15.2 2.2 0.047 14.2 2.2 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region Nup54 PF13874.6 KND96762.1 - 0.036 14.2 1.5 0.085 13.0 1.5 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 AT_hook PF02178.19 KND96762.1 - 0.26 11.3 6.0 0.65 10.1 6.0 1.7 1 0 0 1 1 1 0 AT hook motif Occludin_ELL PF07303.13 KND96762.1 - 0.27 12.0 5.1 0.21 12.3 2.8 2.1 2 1 0 2 2 2 0 Occludin homology domain DUF1664 PF07889.12 KND96762.1 - 0.54 10.3 4.0 1.3 9.1 3.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CENP-H PF05837.12 KND96762.1 - 2.8 8.4 8.1 0.74 10.2 4.6 2.1 2 1 0 2 2 2 0 Centromere protein H (CENP-H) ATG16 PF08614.11 KND96762.1 - 5.9 7.1 14.0 0.046 14.0 3.5 2.5 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Cornichon PF03311.14 KND96763.1 - 2.5e-43 147.3 4.7 2.8e-43 147.1 4.7 1.0 1 0 0 1 1 1 1 Cornichon protein MAP17 PF15807.5 KND96763.1 - 0.12 12.6 1.7 0.17 12.1 0.9 1.6 1 1 1 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 HRI1 PF16815.5 KND96764.1 - 1.5e-44 152.4 0.3 1.7e-44 152.2 0.3 1.0 1 0 0 1 1 1 1 Protein HRI1 LRR_4 PF12799.7 KND96765.1 - 1.4e-23 82.5 64.3 5.2e-05 23.5 8.2 9.5 8 1 1 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KND96765.1 - 1.2e-21 76.3 62.6 1.5e-05 24.7 4.8 8.0 5 2 2 7 7 7 6 Leucine rich repeat LRR_9 PF14580.6 KND96765.1 - 7.2e-06 25.6 23.3 0.0063 16.0 1.9 4.3 2 1 1 3 3 3 3 Leucine-rich repeat DUF4642 PF15484.6 KND96765.1 - 0.026 14.7 0.3 0.093 13.0 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) LRR_1 PF00560.33 KND96765.1 - 0.98 10.2 39.3 74 4.5 0.1 11.7 9 2 0 9 9 9 0 Leucine Rich Repeat LRR_6 PF13516.6 KND96765.1 - 2.1 8.6 47.0 3.5 7.9 0.2 10.7 10 0 0 10 10 10 0 Leucine Rich repeat RRM_1 PF00076.22 KND96766.1 - 3.8e-39 132.4 0.0 3.7e-14 52.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KND96766.1 - 0.00065 19.5 0.0 0.022 14.6 0.0 2.8 4 0 0 4 4 4 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KND96766.1 - 0.0021 18.1 0.0 0.021 14.8 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KND96766.1 - 0.03 14.4 0.0 0.34 11.1 0.0 2.6 3 0 0 3 3 3 0 RNA recognition motif RRM_3 PF08777.11 KND96766.1 - 0.11 12.6 0.0 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif AAA_15 PF13175.6 KND96767.1 - 0.15 11.8 6.0 0.28 10.9 5.6 1.6 1 1 1 2 2 2 0 AAA ATPase domain Poxvirus_B22R PF04395.12 KND96767.1 - 1.3 8.5 4.7 0.46 10.0 2.1 1.5 1 1 0 1 1 1 0 Poxvirus B22R protein PmbA_TldD PF01523.16 KND96767.1 - 5.7 6.7 7.6 9 6.0 7.6 1.3 1 0 0 1 1 1 0 Putative modulator of DNA gyrase Histone PF00125.24 KND96768.1 - 8e-52 175.1 2.1 8.9e-52 174.9 2.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KND96768.1 - 3.5e-06 27.3 0.0 5.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KND96768.1 - 2.6e-05 24.3 0.4 4.3e-05 23.6 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KND96768.1 - 9.3e-05 23.0 0.9 0.00011 22.8 0.9 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KND96768.1 - 0.0013 19.0 0.8 0.0017 18.6 0.1 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KND96768.1 - 0.023 14.8 0.3 0.035 14.2 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Oxidored_q6 PF01058.22 KND96771.1 - 2e-22 79.4 0.1 3.1e-22 78.8 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit EnY2 PF10163.9 KND96772.1 - 3.8e-26 91.3 0.4 4.3e-26 91.1 0.4 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 NUDIX PF00293.28 KND96773.1 - 2.4e-14 53.5 0.0 3.9e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain MukE PF04288.13 KND96775.1 - 0.12 11.3 0.0 0.14 11.1 0.0 1.0 1 0 0 1 1 1 0 MukE-like family TPR_1 PF00515.28 KND96777.1 - 1.8e-53 176.3 24.5 2.2e-07 30.4 0.0 11.1 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 KND96777.1 - 5.4e-51 166.6 21.2 1.1e-06 28.2 0.0 10.8 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 KND96777.1 - 1e-33 112.7 11.9 9.8e-05 22.3 0.0 11.3 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_17 PF13431.6 KND96777.1 - 2.3e-31 105.9 14.7 0.00023 21.3 0.0 10.1 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 KND96777.1 - 1.1e-27 95.4 24.7 5.3e-06 26.0 0.0 9.6 5 3 4 9 9 9 8 TPR repeat TPR_14 PF13428.6 KND96777.1 - 2.8e-24 83.7 25.7 4.1e-05 24.0 0.1 10.0 4 2 6 10 10 9 6 Tetratricopeptide repeat TPR_16 PF13432.6 KND96777.1 - 4.8e-20 71.9 26.7 2.2e-05 25.0 0.0 7.5 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 KND96777.1 - 2.3e-19 69.4 29.3 0.00038 20.7 0.4 8.2 6 2 2 8 8 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 KND96777.1 - 5.5e-19 66.7 8.4 0.1 12.7 0.1 9.2 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 KND96777.1 - 1.3e-18 67.2 30.2 0.0006 20.3 0.4 8.1 5 3 1 7 7 6 6 Tetratricopeptide repeat TPR_9 PF13371.6 KND96777.1 - 8.1e-17 61.1 20.8 0.0031 17.6 0.3 6.8 4 3 2 7 7 6 6 Tetratricopeptide repeat TPR_6 PF13174.6 KND96777.1 - 2e-15 56.3 20.9 0.011 16.3 0.0 10.0 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_15 PF13429.6 KND96777.1 - 2.6e-07 30.2 20.9 0.0064 15.7 0.1 5.2 3 3 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KND96777.1 - 1.1e-06 28.8 18.6 4.1e-05 23.7 0.4 4.1 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KND96777.1 - 0.026 14.4 19.3 7.5 6.6 0.0 7.6 9 0 0 9 9 8 0 Tetratricopeptide repeat RPN7 PF10602.9 KND96777.1 - 0.07 12.8 1.7 12 5.6 0.0 4.2 5 1 0 5 5 5 0 26S proteasome subunit RPN7 NARP1 PF12569.8 KND96777.1 - 0.12 11.2 0.0 0.12 11.2 0.0 7.0 6 2 2 8 8 6 0 NMDA receptor-regulated protein 1 NAD_kinase PF01513.21 KND96778.1 - 6.2e-51 173.3 0.0 8.4e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KND96778.1 - 0.0022 17.6 0.1 0.0043 16.7 0.1 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Hist_deacetyl PF00850.19 KND96779.1 - 8.3e-83 278.4 0.0 1.1e-82 278.0 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DHHC PF01529.20 KND96781.1 - 4.4e-20 72.2 11.6 6e-20 71.7 11.6 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase UAA PF08449.11 KND96782.1 - 7.7e-44 150.1 17.0 9.5e-44 149.8 17.0 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KND96782.1 - 1.3e-07 31.9 25.6 3e-05 24.2 10.0 3.2 3 0 0 3 3 3 3 EamA-like transporter family Nuc_sug_transp PF04142.15 KND96782.1 - 0.0001 21.6 10.5 0.00013 21.3 10.5 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 KND96782.1 - 0.00033 20.1 9.9 0.0011 18.4 2.3 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family SRP68 PF16969.5 KND96783.1 - 2.7e-53 181.8 16.2 3.6e-53 181.4 16.2 1.1 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 DnaJ PF00226.31 KND96784.1 - 3.5e-20 71.9 1.0 7.1e-20 70.9 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 KND96784.1 - 0.038 13.9 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 A repeated domain in UCH-protein RRM_1 PF00076.22 KND96784.1 - 0.057 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyt-b5 PF00173.28 KND96785.1 - 7.5e-26 90.1 0.1 9.6e-26 89.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HD PF01966.22 KND96786.1 - 5.3e-10 39.6 0.0 8.1e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 HD domain RRM_1 PF00076.22 KND96787.1 - 1.2e-15 57.0 0.1 2.4e-15 56.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KND96787.1 - 0.0033 17.4 0.6 0.0078 16.2 0.2 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Maf PF02545.14 KND96788.1 - 2.1e-37 128.5 0.0 2.4e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein His_Phos_1 PF00300.22 KND96790.1 - 1.4e-18 67.3 0.0 2.9e-18 66.3 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 2-oxoacid_dh PF00198.23 KND96792.1 - 1.6e-74 250.3 0.4 2e-74 250.0 0.4 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KND96792.1 - 1.3e-17 63.4 0.1 2.6e-17 62.4 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KND96792.1 - 3e-14 53.1 0.2 7.6e-14 51.8 0.2 1.7 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.8 KND96792.1 - 0.056 13.9 0.0 0.16 12.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) PA_decarbox PF05870.11 KND96792.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) RNA_pol_Rpc4 PF05132.14 KND96792.1 - 0.078 13.4 1.5 0.17 12.3 1.5 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 Ribosomal_60s PF00428.19 KND96792.1 - 5.6 7.6 20.8 0.99 10.0 13.7 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein RNase_HII PF01351.18 KND96793.1 - 5.9e-57 192.7 0.0 7.5e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII CelTOS PF18659.1 KND96793.1 - 0.12 12.9 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites Mito_carr PF00153.27 KND96794.1 - 1.3e-62 207.7 6.2 1.2e-21 76.5 0.1 3.5 2 1 1 3 3 3 3 Mitochondrial carrier protein Syja_N PF02383.18 KND96796.1 - 1.5e-72 244.7 1.8 1.1e-71 241.8 0.3 2.3 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.23 KND96796.1 - 2.8e-12 46.7 0.0 5.9e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YEATS PF03366.16 KND96797.1 - 6.3e-32 109.4 1.0 1.1e-31 108.6 1.0 1.4 1 0 0 1 1 1 1 YEATS family Luteo_coat PF00894.18 KND96798.1 - 0.19 11.6 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Luteovirus coat protein Sec23_trunk PF04811.15 KND96799.1 - 7.9e-49 166.4 0.0 1.1e-47 162.6 0.0 2.1 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KND96799.1 - 1.9e-28 99.0 0.0 4.3e-28 97.9 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KND96799.1 - 1.2e-18 66.8 0.1 2.6e-18 65.7 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 KND96799.1 - 3.7e-11 42.8 0.0 8.8e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 KND96799.1 - 1.5e-09 37.7 2.3 3.2e-09 36.7 2.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger tRNA-synt_2 PF00152.20 KND96800.1 - 6.3e-65 219.3 0.0 8.6e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KND96800.1 - 2e-07 30.9 0.1 3.6e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KND96800.1 - 0.00044 19.8 0.1 0.074 12.5 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti_2 PF13742.6 KND96800.1 - 0.096 12.9 0.0 0.42 10.8 0.0 2.0 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain RhoGAP PF00620.27 KND96801.1 - 6.8e-37 126.6 0.0 1.8e-36 125.3 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.19 KND96801.1 - 7.4e-19 68.6 2.4 2.1e-14 54.1 0.1 3.6 3 0 0 3 3 3 2 RasGEF domain RasGEF_N PF00618.20 KND96801.1 - 1.8e-13 50.6 2.7 1e-12 48.2 2.7 2.4 1 0 0 1 1 1 1 RasGEF N-terminal motif 60KD_IMP PF02096.20 KND96802.1 - 2.4e-24 86.1 1.1 2.4e-24 86.1 1.1 1.5 2 0 0 2 2 2 1 60Kd inner membrane protein SMC_N PF02463.19 KND96804.1 - 2.6e-15 56.5 45.6 1.9e-14 53.7 45.6 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KND96804.1 - 3.9e-10 40.0 23.7 3.9e-10 40.0 23.7 3.9 1 1 2 3 3 3 1 AAA ATPase domain AAA_23 PF13476.6 KND96804.1 - 1.5e-08 35.4 46.6 1.5e-08 35.4 46.6 6.5 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KND96804.1 - 4.2e-07 30.1 14.3 0.00014 21.8 3.1 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF3584 PF12128.8 KND96804.1 - 0.00017 19.3 28.2 0.00017 19.3 28.2 3.7 2 2 1 3 3 3 1 Protein of unknown function (DUF3584) PI3K_P85_iSH2 PF16454.5 KND96804.1 - 0.00095 18.8 16.9 0.00095 18.8 16.9 5.8 2 2 2 4 4 4 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain AAA_29 PF13555.6 KND96804.1 - 0.0014 18.3 0.1 0.0028 17.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain KxDL PF10241.9 KND96804.1 - 0.0053 17.0 6.2 0.0053 17.0 6.2 6.6 5 1 0 6 6 6 1 Uncharacterized conserved protein SMC_hinge PF06470.13 KND96804.1 - 0.014 15.7 0.1 0.06 13.7 0.0 2.2 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain SSF PF00474.17 KND96806.1 - 1.3e-06 27.5 26.2 2e-06 26.9 24.6 2.0 1 1 0 1 1 1 1 Sodium:solute symporter family Holin_BlyA PF05102.12 KND96806.1 - 0.18 11.8 2.0 0.79 9.7 2.0 2.1 1 0 0 1 1 1 0 holin, BlyA family Ycf70 PF17382.2 KND96806.1 - 0.29 11.6 3.2 0.82 10.1 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized Ycf70-like Haem_degrading PF03928.14 KND96808.1 - 1e-30 106.2 0.0 1.2e-30 106.0 0.0 1.0 1 0 0 1 1 1 1 Haem-degrading RE_Bpu10I PF09549.10 KND96808.1 - 0.04 13.5 0.0 0.14 11.7 0.0 1.9 1 1 1 2 2 2 0 Bpu10I restriction endonuclease Hydrolase_2 PF07486.12 KND96808.1 - 0.07 14.0 0.0 0.098 13.5 0.0 1.3 1 0 0 1 1 1 0 Cell Wall Hydrolase CMD PF02627.20 KND96811.1 - 3.3e-05 23.8 0.0 0.0068 16.4 0.0 2.4 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family CENP-U PF13097.6 KND96811.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit AFG1_ATPase PF03969.16 KND96812.1 - 3.3e-58 197.3 2.2 1.2e-55 188.9 0.4 3.6 2 1 0 3 3 3 1 AFG1-like ATPase AAA_22 PF13401.6 KND96812.1 - 0.018 15.3 0.0 0.066 13.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KND96812.1 - 0.019 15.5 0.3 3.7 8.1 0.0 3.3 3 0 0 3 3 3 0 ABC transporter NACHT PF05729.12 KND96812.1 - 0.026 14.4 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 KND96812.1 - 0.052 13.9 0.1 1.1 9.7 0.0 3.0 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 KND96812.1 - 0.06 13.7 0.0 0.28 11.6 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain ATP_Ca_trans_C PF12424.8 KND96812.1 - 0.074 13.6 0.0 3.4 8.2 0.0 2.8 2 0 0 2 2 2 0 Plasma membrane calcium transporter ATPase C terminal AAA PF00004.29 KND96812.1 - 0.095 13.1 0.0 0.25 11.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KND96812.1 - 0.18 11.6 0.0 0.5 10.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Myotub-related PF06602.14 KND96813.1 - 1.2e-141 471.7 0.1 1.5e-141 471.4 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 KND96813.1 - 0.0023 17.9 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KND96813.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 KND96813.1 - 0.028 14.2 0.0 0.088 12.6 0.0 1.8 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain HTH_29 PF13551.6 KND96813.1 - 0.13 12.4 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix DUF4758 PF15950.5 KND96814.1 - 2.8 8.3 5.6 2.9 8.2 1.2 2.7 2 1 0 2 2 2 0 Putative sperm flagellar membrane protein Oxysterol_BP PF01237.18 KND96815.1 - 2.5e-134 447.8 0.0 4.9e-134 446.9 0.0 1.5 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_5 PF13857.6 KND96815.1 - 7.2e-16 58.1 0.1 1.2e-08 35.0 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KND96815.1 - 1.3e-14 54.4 0.0 1.5e-09 38.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KND96815.1 - 5.1e-14 52.6 0.0 2.6e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND96815.1 - 3.2e-12 45.5 0.0 0.00044 20.5 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KND96815.1 - 1.4e-08 34.8 0.0 0.00015 22.0 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeat PH_8 PF15409.6 KND96815.1 - 3.1e-08 33.8 0.2 7.6e-08 32.5 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KND96815.1 - 5.6e-08 33.2 0.1 1.5e-07 31.9 0.1 1.8 1 0 0 1 1 1 1 PH domain EMP24_GP25L PF01105.24 KND96817.1 - 4.7e-23 82.1 2.5 4.7e-23 82.1 2.5 1.6 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD ECR1_N PF14382.6 KND96818.1 - 2.9e-12 46.2 0.3 1.9e-11 43.6 0.0 2.3 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KND96818.1 - 6.5e-08 32.8 0.1 1.3e-07 31.9 0.1 1.5 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 KND96818.1 - 0.0045 17.6 0.2 1.1 9.8 0.0 3.1 2 1 0 3 3 3 1 Exosome component EXOSC1/CSL4 MtaB PF12176.8 KND96818.1 - 0.1 11.4 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit Met_10 PF02475.16 KND96819.1 - 2.7e-66 223.1 0.0 8.6e-66 221.5 0.0 1.8 1 1 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 KND96819.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase RNase_H2_suC PF08615.11 KND96821.1 - 4.3e-12 46.4 0.1 1.8e-10 41.2 0.1 2.0 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) OTCace PF00185.24 KND96822.1 - 1.3e-46 158.6 0.4 2e-46 157.9 0.4 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KND96822.1 - 5.8e-40 136.7 0.1 9.4e-40 136.0 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Glyco_hydro_4 PF02056.16 KND96822.1 - 0.00027 20.5 0.0 0.00068 19.2 0.0 1.6 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase DNA_pol_B_3 PF08408.10 KND96822.1 - 0.0027 17.9 0.2 0.0063 16.7 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B viral insert Sugar_tr PF00083.24 KND96826.1 - 1.9e-155 518.2 29.4 2.2e-155 518.0 29.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND96826.1 - 7.8e-29 100.7 28.8 3.7e-25 88.6 16.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ni_hydr_CYTB PF01292.20 KND96826.1 - 0.11 12.1 3.2 0.74 9.4 1.2 2.7 3 0 0 3 3 3 0 Prokaryotic cytochrome b561 LMF1 PF06762.14 KND96826.1 - 0.72 8.9 7.5 0.17 11.0 4.3 1.5 2 0 0 2 2 2 0 Lipase maturation factor RRM_1 PF00076.22 KND96827.1 - 4.8e-17 61.5 0.1 8e-08 32.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KND96827.1 - 6.2e-08 32.3 0.1 3.9e-06 26.5 0.1 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KND96827.1 - 0.037 14.1 0.1 0.27 11.3 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 Phage_TAC_4 PF08748.11 KND96827.1 - 0.06 13.7 0.9 0.1 12.9 0.9 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone bZIP_2 PF07716.15 KND96828.1 - 1.3e-07 31.5 13.0 2.5e-07 30.7 13.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KND96828.1 - 2.7e-07 30.6 11.2 5.7e-07 29.5 11.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor HNF-1_N PF04814.13 KND96828.1 - 0.004 17.8 0.9 0.0058 17.3 0.9 1.3 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Uds1 PF15456.6 KND96828.1 - 0.064 13.4 5.9 0.11 12.6 5.9 1.4 1 1 0 1 1 1 0 Up-regulated During Septation HALZ PF02183.18 KND96828.1 - 0.13 12.5 4.3 0.1 12.8 2.1 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper PRCC PF10253.9 KND96828.1 - 0.14 12.9 3.2 0.21 12.4 3.2 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting bZIP_Maf PF03131.17 KND96828.1 - 1.2 9.8 9.8 0.11 13.0 5.0 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor TUG-UBL1 PF11470.8 KND96830.1 - 2.6e-16 59.6 2.7 6.9e-16 58.2 2.7 1.8 1 0 0 1 1 1 1 TUG ubiquitin-like domain YebO PF13974.6 KND96830.1 - 0.74 9.9 3.9 1.9 8.6 3.9 1.8 1 0 0 1 1 1 0 YebO-like protein CSRNP_N PF16019.5 KND96830.1 - 1.2 9.0 5.0 3 7.7 5.0 1.6 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus TMPIT PF07851.13 KND96830.1 - 5.6 6.1 5.7 9.9 5.3 5.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein Abhydrolase_6 PF12697.7 KND96833.1 - 1.2e-13 52.2 0.0 1.9e-13 51.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KND96833.1 - 6.3e-13 49.0 0.1 2.8e-12 46.8 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KND96833.1 - 5e-08 32.5 0.0 0.0001 21.6 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DUF915 PF06028.11 KND96833.1 - 0.013 14.9 0.0 0.033 13.5 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) MutS_V PF00488.21 KND96834.1 - 1.3e-69 234.0 0.1 3e-69 232.8 0.1 1.7 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 KND96834.1 - 4.4e-30 104.2 0.0 1.4e-29 102.6 0.0 1.9 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 KND96834.1 - 2.1e-28 99.9 0.6 3.8e-28 99.0 0.6 1.5 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 KND96834.1 - 3e-11 43.8 0.3 9.9e-11 42.1 0.3 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KND96834.1 - 6.4e-08 32.8 0.6 1.6e-07 31.6 0.1 2.0 2 0 0 2 2 2 1 MutS family domain IV AAA_14 PF13173.6 KND96834.1 - 0.043 13.9 0.3 0.46 10.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain Ank_2 PF12796.7 KND96836.1 - 5.9e-13 49.2 1.9 5.9e-05 23.6 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND96836.1 - 7.3e-11 42.4 4.6 2.7e-05 24.6 0.1 5.2 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KND96836.1 - 2.7e-06 27.5 1.7 0.00037 20.7 0.0 4.3 6 0 0 6 6 6 1 Ankyrin repeats (many copies) Ank PF00023.30 KND96836.1 - 7.7e-05 23.0 5.3 1.9 9.1 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 KND96836.1 - 0.0013 19.0 3.5 0.15 12.7 0.0 4.6 6 0 0 6 6 6 1 Ankyrin repeat DUF2433 PF10360.9 KND96838.1 - 6.3e-16 58.6 0.0 2.6e-15 56.6 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.7 KND96838.1 - 0.0022 18.2 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KND96838.1 - 0.0058 17.1 0.1 0.017 15.6 0.1 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase YAcAr PF10686.9 KND96838.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family Gal4_dimer PF03902.13 KND96838.1 - 0.22 11.7 2.3 3.1 8.0 0.7 2.6 2 0 0 2 2 2 0 Gal4-like dimerisation domain NADH_B2 PF14813.6 KND96839.1 - 1.1e-05 25.1 0.4 1.1e-05 25.1 0.4 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 RhodobacterPufX PF11511.8 KND96842.1 - 0.77 9.4 3.1 1.6 8.4 3.1 1.5 1 1 0 1 1 1 0 Intrinsic membrane protein PufX ABC_tran PF00005.27 KND96844.1 - 2.4e-48 164.1 0.0 3.2e-24 86.0 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 KND96844.1 - 2.7e-30 105.4 33.4 1.7e-16 60.3 12.2 2.5 2 0 0 2 2 2 2 ABC-2 type transporter RsgA_GTPase PF03193.16 KND96844.1 - 2.6e-10 40.5 0.1 0.00014 21.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 KND96844.1 - 1.5e-09 38.1 13.6 0.00013 21.9 0.1 4.4 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KND96844.1 - 3.6e-08 34.2 1.7 0.0052 17.3 0.2 3.0 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KND96844.1 - 7.2e-08 32.8 0.5 0.0055 17.0 0.2 3.0 3 1 0 3 3 2 2 AAA domain SMC_N PF02463.19 KND96844.1 - 1.6e-07 31.0 4.5 0.0021 17.6 0.0 3.9 3 2 0 3 3 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KND96844.1 - 2.4e-07 31.3 0.2 0.0046 17.4 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 KND96844.1 - 3.6e-07 30.6 0.2 0.035 14.4 0.1 3.0 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 KND96844.1 - 2.6e-06 27.1 0.1 0.037 13.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 KND96844.1 - 4e-06 27.2 0.0 0.057 13.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA PF00004.29 KND96844.1 - 1.8e-05 25.2 0.1 0.18 12.2 0.0 3.8 3 1 1 4 4 3 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KND96844.1 - 2e-05 24.6 0.0 0.1 12.5 0.0 2.6 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea Rad17 PF03215.15 KND96844.1 - 2.5e-05 24.3 0.2 0.052 13.5 0.0 2.7 3 0 0 3 3 2 2 Rad17 P-loop domain AAA_18 PF13238.6 KND96844.1 - 4.4e-05 24.0 0.0 0.36 11.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 KND96844.1 - 6e-05 22.2 0.1 0.17 10.9 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein IstB_IS21 PF01695.17 KND96844.1 - 6.8e-05 22.7 0.0 3 7.6 0.0 3.8 4 0 0 4 4 4 1 IstB-like ATP binding protein NACHT PF05729.12 KND96844.1 - 0.00016 21.6 0.0 0.28 11.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_30 PF13604.6 KND96844.1 - 0.00025 20.8 0.1 0.26 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KND96844.1 - 0.00027 21.1 0.1 1.2 9.4 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit dNK PF01712.19 KND96844.1 - 0.00068 19.5 0.0 0.51 10.1 0.0 2.6 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_14 PF13173.6 KND96844.1 - 0.00072 19.6 0.0 0.22 11.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KND96844.1 - 0.0011 18.7 0.1 1.6 8.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KND96844.1 - 0.0013 18.8 0.2 0.34 11.0 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_19 PF13245.6 KND96844.1 - 0.0015 18.9 0.0 0.13 12.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KND96844.1 - 0.0015 18.5 0.0 0.21 11.6 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 KND96844.1 - 0.0024 17.5 0.2 0.65 9.6 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Pox_A32 PF04665.12 KND96844.1 - 0.003 17.1 0.1 0.67 9.4 0.0 2.5 2 0 0 2 2 2 1 Poxvirus A32 protein cobW PF02492.19 KND96844.1 - 0.0036 16.9 0.8 1.6 8.3 0.1 2.7 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain PRK PF00485.18 KND96844.1 - 0.0045 16.7 0.2 0.22 11.2 0.1 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 KND96844.1 - 0.0049 17.0 0.0 5 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 KND96844.1 - 0.0074 15.7 0.1 0.44 9.9 0.0 2.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit FtsK_SpoIIIE PF01580.18 KND96844.1 - 0.0082 15.5 1.7 0.55 9.5 0.1 2.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family RuvB_N PF05496.12 KND96844.1 - 0.0086 15.8 0.0 0.53 10.0 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 KND96844.1 - 0.0093 15.9 0.1 7.2 6.5 0.0 3.2 3 0 0 3 3 3 0 NTPase MobB PF03205.14 KND96844.1 - 0.015 15.2 0.3 0.64 9.9 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.17 KND96844.1 - 0.019 14.8 0.3 4.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 KND96844.1 - 0.02 14.5 0.0 6.8 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KND96844.1 - 0.021 14.1 0.2 1.5 8.1 0.0 3.2 3 0 0 3 3 3 0 KaiC AAA_5 PF07728.14 KND96844.1 - 0.024 14.7 0.1 9 6.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KND96844.1 - 0.029 13.9 0.0 2 7.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_13 PF13166.6 KND96844.1 - 0.03 13.0 0.0 14 4.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain Septin PF00735.18 KND96844.1 - 0.03 13.6 0.1 2.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_17 PF13207.6 KND96844.1 - 0.043 14.2 0.0 1.5 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KND96844.1 - 0.049 12.9 0.0 0.56 9.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Thymidylate_kin PF02223.17 KND96844.1 - 0.051 13.2 0.1 4.3 7.0 0.0 2.7 2 0 0 2 2 2 0 Thymidylate kinase NB-ARC PF00931.22 KND96844.1 - 0.067 12.4 0.9 0.3 10.3 0.0 2.3 2 1 1 3 3 3 0 NB-ARC domain Cytidylate_kin PF02224.18 KND96844.1 - 0.084 12.6 0.0 7.1 6.3 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase DUF87 PF01935.17 KND96844.1 - 0.14 12.3 2.7 0.41 10.7 0.0 2.9 3 0 0 3 3 2 0 Helicase HerA, central domain PduV-EutP PF10662.9 KND96844.1 - 0.14 11.9 0.1 4.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 KND96844.1 - 0.14 11.6 0.0 11 5.4 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Ribonuc_red_2_N PF08471.10 KND96844.1 - 0.16 12.2 0.7 0.65 10.2 0.4 2.3 2 0 0 2 2 1 0 Class II vitamin B12-dependent ribonucleotide reductase Glutaredoxin PF00462.24 KND96846.1 - 1.4e-17 63.7 0.0 2e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Pkinase PF00069.25 KND96848.1 - 1.3e-68 231.3 0.0 2e-68 230.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND96848.1 - 3.6e-28 98.6 0.0 9.1e-28 97.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND96848.1 - 9e-05 21.9 2.4 0.9 8.8 0.0 3.1 2 1 1 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 KND96848.1 - 0.0043 15.9 0.0 0.007 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KND96848.1 - 0.019 14.4 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND96848.1 - 0.15 12.0 0.0 7.5 6.4 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family PI3K_1B_p101 PF10486.9 KND96848.1 - 0.34 8.6 7.8 0.53 8.0 7.8 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PPP4R2 PF09184.11 KND96848.1 - 1.6 8.3 16.6 0.91 9.1 14.0 1.8 2 0 0 2 2 2 0 PPP4R2 SDA1 PF05285.12 KND96848.1 - 3 7.2 13.7 6.1 6.2 13.7 1.5 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KND96848.1 - 3 5.9 15.5 4.4 5.4 15.5 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KND96848.1 - 4 6.7 15.4 7.6 5.8 15.4 1.4 1 0 0 1 1 1 0 BUD22 DUF3561 PF12084.8 KND96849.1 - 0.12 12.4 0.1 0.18 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3561) AP3D1 PF06375.11 KND96849.1 - 3.6 7.8 8.7 4 7.7 8.7 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 MARVEL PF01284.23 KND96851.1 - 0.024 14.6 0.0 0.025 14.6 0.0 1.0 1 0 0 1 1 1 0 Membrane-associating domain Npa1 PF11707.8 KND96852.1 - 2.9e-64 217.6 8.7 3.7e-64 217.2 5.3 2.7 3 0 0 3 3 3 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KND96852.1 - 8.5e-39 133.2 1.1 6.1e-37 127.2 0.0 2.8 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 Chordopox_A13L PF05961.11 KND96852.1 - 0.059 13.6 0.1 0.17 12.2 0.1 1.8 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DEK_C PF08766.11 KND96852.1 - 1 9.3 4.1 1.6 8.7 0.2 3.1 3 0 0 3 3 3 0 DEK C terminal domain AAA_12 PF13087.6 KND96854.1 - 2.8e-60 203.3 0.0 1.2e-59 201.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KND96854.1 - 3.8e-55 187.5 0.0 6.6e-55 186.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KND96854.1 - 8e-10 39.2 0.0 2.7e-08 34.3 0.0 3.2 2 2 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KND96854.1 - 8.9e-10 38.6 0.0 5.5e-07 29.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 KND96854.1 - 8.1e-09 35.6 0.1 0.011 15.5 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KND96854.1 - 7.7e-05 22.8 0.0 0.00025 21.1 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KND96854.1 - 0.00011 21.8 0.0 0.023 14.1 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein Helicase_RecD PF05127.14 KND96854.1 - 0.00028 20.8 0.0 0.011 15.6 0.0 2.8 3 0 0 3 3 3 1 Helicase AAA_22 PF13401.6 KND96854.1 - 0.00041 20.6 0.4 0.0057 16.9 0.0 3.1 5 0 0 5 5 4 1 AAA domain PIF1 PF05970.14 KND96854.1 - 0.0012 18.1 0.0 0.059 12.5 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase AAA_33 PF13671.6 KND96854.1 - 0.0027 17.9 0.0 0.0062 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KND96854.1 - 0.0031 17.9 0.2 0.014 15.8 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KND96854.1 - 0.0041 17.6 0.2 0.017 15.5 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 KND96854.1 - 0.0041 16.7 0.0 0.0086 15.6 0.0 1.7 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_23 PF13476.6 KND96854.1 - 0.0054 17.3 1.5 0.0054 17.3 1.5 2.3 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.14 KND96854.1 - 0.0071 16.3 0.0 0.3 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 KND96854.1 - 0.013 14.8 0.0 0.032 13.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 KND96854.1 - 0.032 13.3 0.1 0.059 12.4 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD_C_2 PF13538.6 KND96854.1 - 0.035 13.9 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_24 PF13479.6 KND96854.1 - 0.039 13.7 0.0 0.41 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KND96854.1 - 0.047 14.2 0.0 0.14 12.7 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 KND96854.1 - 0.056 13.0 0.0 0.16 11.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain CAP PF00188.26 KND96855.1 - 1.7e-19 70.9 3.6 4e-19 69.7 3.6 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SR-25 PF10500.9 KND96855.1 - 2 8.0 6.0 2.7 7.6 6.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Fungal_trans PF04082.18 KND96857.1 - 8.3e-13 48.0 0.1 1.6e-12 47.1 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND96857.1 - 1e-06 28.8 8.7 1.6e-06 28.1 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MSA_2 PF00985.17 KND96857.1 - 0.015 15.7 0.2 0.044 14.1 0.2 1.8 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Filament PF00038.21 KND96857.1 - 0.069 12.7 0.3 0.13 11.8 0.3 1.4 1 0 0 1 1 1 0 Intermediate filament protein Lipoprotein_20 PF13942.6 KND96857.1 - 0.1 12.5 2.6 1.3 9.0 0.2 2.3 2 0 0 2 2 2 0 YfhG lipoprotein TFIIA PF03153.13 KND96858.1 - 0.053 13.5 33.3 0.073 13.0 33.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 KND96858.1 - 8.8 5.8 13.7 14 5.1 13.7 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ETF PF01012.21 KND96859.1 - 6.3e-42 143.5 0.9 6.3e-42 143.5 0.9 1.5 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KND96859.1 - 1.1e-33 115.1 0.2 2.2e-33 114.1 0.2 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Sulfate_transp PF00916.20 KND96864.1 - 1.6e-57 195.0 3.2 2.1e-57 194.6 3.2 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KND96864.1 - 1.7e-16 59.9 0.0 3.4e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KND96864.1 - 0.0018 18.6 3.3 0.0018 18.6 3.3 2.7 3 0 0 3 3 3 1 Molybdate transporter of MFS superfamily DUF1427 PF07235.11 KND96864.1 - 0.033 14.1 0.1 0.09 12.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1427) CAF1C_H4-bd PF12265.8 KND96865.1 - 2e-22 79.2 0.2 4.9e-22 78.0 0.2 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KND96865.1 - 5.1e-19 68.3 13.4 1.6e-06 28.7 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat BING4CT PF08149.11 KND96865.1 - 0.0049 16.6 0.1 6.7 6.6 0.0 3.6 4 0 0 4 4 4 1 BING4CT (NUC141) domain RCC1_2 PF13540.6 KND96865.1 - 0.15 11.9 0.1 0.35 10.7 0.1 1.6 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat Acetyltransf_1 PF00583.25 KND96866.1 - 1.9e-15 57.1 0.0 5.6e-15 55.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KND96866.1 - 5.9e-15 55.3 0.0 9.5e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KND96866.1 - 6.5e-09 36.1 0.0 1e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KND96866.1 - 0.0019 18.2 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KND96866.1 - 0.0067 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KND96866.1 - 0.094 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase CENP-B_dimeris PF09026.10 KND96866.1 - 0.1 13.0 2.6 0.17 12.3 2.6 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Acetyltransf_8 PF13523.6 KND96866.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SAM35 PF10806.8 KND96867.1 - 1.4e-25 90.0 0.0 3.1e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 SAM35, subunit of SAM coomplex JAB PF01398.21 KND96868.1 - 1.4e-31 108.9 0.2 1.4e-31 108.9 0.2 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KND96868.1 - 4.7e-13 49.5 2.2 1.1e-12 48.4 2.2 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KND96868.1 - 1.1e-07 31.7 0.0 1.6e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Peptidase_M24 PF00557.24 KND96870.1 - 1.1e-56 191.8 0.0 1.4e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KND96870.1 - 9.2e-20 70.6 0.0 2.1e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain GDI PF00996.18 KND96871.1 - 4.2e-219 727.4 0.3 4.9e-219 727.2 0.3 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KND96871.1 - 0.12 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Asp_protease PF09668.10 KND96872.1 - 1.6e-40 137.7 0.0 2.3e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KND96872.1 - 6.3e-18 65.1 0.0 4e-17 62.6 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease ubiquitin PF00240.23 KND96872.1 - 4.2e-12 45.6 0.0 8.4e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Asp_protease_2 PF13650.6 KND96872.1 - 5.6e-10 39.7 0.0 1.7e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 KND96872.1 - 4.1e-06 27.0 0.0 1.3e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 KND96872.1 - 5.9e-06 26.1 0.2 2.2e-05 24.2 0.1 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease Ubiquitin_2 PF14560.6 KND96872.1 - 0.00037 20.9 0.0 0.00075 19.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 KND96872.1 - 0.0007 19.4 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like LSM PF01423.22 KND96873.1 - 1.3e-17 63.2 0.2 1.7e-17 62.8 0.2 1.2 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 KND96873.1 - 0.00051 20.1 0.9 0.0029 17.7 0.2 2.0 1 1 1 2 2 2 1 RimP C-terminal SH3 domain SM-ATX PF14438.6 KND96873.1 - 0.0011 19.0 0.1 0.0017 18.4 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Hfq PF17209.3 KND96873.1 - 0.025 14.2 0.1 0.061 13.0 0.1 1.6 2 0 0 2 2 2 0 Hfq protein Response_reg PF00072.24 KND96874.1 - 1.8e-19 70.0 0.0 1.2e-13 51.2 0.0 2.4 1 1 0 2 2 2 2 Response regulator receiver domain AreA_N PF07573.11 KND96874.1 - 0.043 14.5 2.4 0.13 12.9 2.4 1.8 1 0 0 1 1 1 0 Nitrogen regulatory protein AreA N terminus BSD PF03909.17 KND96876.1 - 2.6e-17 62.5 1.6 2.6e-17 62.5 1.6 3.1 3 0 0 3 3 3 1 BSD domain NPV_P10 PF05531.12 KND96876.1 - 0.05 14.1 10.6 0.056 13.9 4.1 3.4 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein FWWh PF14922.6 KND96876.1 - 0.064 13.2 1.2 0.11 12.5 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function Med21 PF11221.8 KND96876.1 - 0.09 13.0 11.8 0.028 14.7 1.6 3.1 1 1 0 2 2 2 0 Subunit 21 of Mediator complex HsbA PF12296.8 KND96876.1 - 0.12 12.8 0.5 0.12 12.8 0.5 2.6 2 1 1 3 3 3 0 Hydrophobic surface binding protein A Sulfatase_C PF14707.6 KND96876.1 - 0.28 11.9 11.3 0.86 10.4 0.2 3.9 2 2 0 2 2 2 0 C-terminal region of aryl-sulfatase Baculo_PEP_C PF04513.12 KND96876.1 - 0.51 10.4 10.5 5.7 7.0 4.1 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 KND96876.1 - 1 7.2 12.1 0.88 7.5 10.6 1.6 2 0 0 2 2 2 0 Prominin Allexi_40kDa PF05549.11 KND96876.1 - 1.5 8.3 9.7 0.14 11.7 1.8 2.3 2 1 2 4 4 4 0 Allexivirus 40kDa protein Lectin_N PF03954.14 KND96876.1 - 3.2 7.5 11.0 0.7 9.6 1.0 3.5 2 1 2 4 4 4 0 Hepatic lectin, N-terminal domain ZapA PF05164.13 KND96876.1 - 5.7 7.4 19.3 7.4 7.1 8.5 4.0 2 2 1 3 3 3 0 Cell division protein ZapA ABC_tran PF00005.27 KND96877.1 - 9.2e-22 78.0 0.1 2.2e-11 44.4 0.0 3.0 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 KND96877.1 - 8.4e-06 25.8 0.0 0.0033 17.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KND96877.1 - 9.8e-06 25.7 0.0 0.14 12.4 0.0 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 KND96877.1 - 0.034 14.4 0.1 6 7.1 0.1 3.2 2 1 0 2 2 2 0 AAA domain Aminotran_1_2 PF00155.21 KND96878.1 - 5.3e-62 210.1 0.0 6.6e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KND96878.1 - 0.0052 16.1 0.0 0.0067 15.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KND96878.1 - 0.048 13.0 0.0 0.27 10.5 0.0 2.0 2 1 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KND96878.1 - 0.25 10.2 0.0 0.37 9.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Y_phosphatase2 PF03162.13 KND96879.1 - 2.8e-42 144.1 0.0 3.6e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KND96879.1 - 0.09 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase UCH PF00443.29 KND96880.1 - 2.5e-60 204.1 2.6 4.3e-60 203.4 2.6 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KND96880.1 - 3.4e-25 89.3 1.1 1.1e-24 87.7 1.1 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-MIZ PF02891.20 KND96880.1 - 0.028 14.1 0.4 0.067 13.0 0.4 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Rhodanese PF00581.20 KND96880.1 - 0.17 12.4 0.0 1.5 9.4 0.0 2.3 2 0 0 2 2 2 0 Rhodanese-like domain IF-2B PF01008.17 KND96881.1 - 7e-67 225.6 0.0 9.2e-67 225.2 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family UPF0052 PF01933.18 KND96882.1 - 3.3e-54 184.1 0.0 6.2e-54 183.2 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised protein family UPF0052 WD40 PF00400.32 KND96883.1 - 5.8e-29 99.7 11.9 5.7e-08 33.3 0.7 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.8 KND96883.1 - 0.00011 21.0 3.1 0.063 11.9 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 KOW PF00467.29 KND96883.1 - 0.16 12.0 0.0 0.96 9.5 0.0 2.3 3 0 0 3 3 3 0 KOW motif WD40 PF00400.32 KND96885.1 - 1.3e-08 35.3 7.5 0.2 12.6 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Mur_ligase_M PF08245.12 KND96886.1 - 4.4e-07 30.1 0.6 1.5e-06 28.3 0.5 2.0 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KND96886.1 - 0.007 16.6 0.0 0.027 14.7 0.0 2.0 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain ANTAR PF03861.14 KND96886.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 ANTAR domain Med11 PF10280.9 KND96887.1 - 2.4e-18 66.9 0.2 3.9e-18 66.2 0.2 1.3 1 0 0 1 1 1 1 Mediator complex protein Sld5 PF05916.11 KND96888.1 - 1.2e-12 48.2 0.5 1.9e-12 47.6 0.5 1.3 1 0 0 1 1 1 1 GINS complex protein DUF3885 PF13021.6 KND96888.1 - 0.084 13.0 0.2 0.2 11.8 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3885) Peptidase_M10_C PF08548.11 KND96888.1 - 0.089 12.7 0.2 0.14 12.0 0.2 1.3 1 0 0 1 1 1 0 Peptidase M10 serralysin C terminal MMM1 PF10296.9 KND96889.1 - 2e-07 30.4 0.1 0.00035 19.7 0.0 2.1 2 0 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 AAA PF00004.29 KND96890.1 - 6.8e-58 194.8 0.0 3.7e-43 147.1 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KND96890.1 - 4.5e-19 68.6 0.1 1.2e-18 67.3 0.1 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KND96890.1 - 2.3e-08 33.7 0.1 8.9e-06 25.4 0.0 2.6 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 KND96890.1 - 7.4e-08 33.0 6.9 0.073 13.5 0.1 4.7 3 2 1 5 5 4 2 AAA ATPase domain ABC_tran PF00005.27 KND96890.1 - 5.1e-07 30.3 2.7 0.00091 19.7 0.1 3.6 3 0 0 3 3 3 2 ABC transporter NACHT PF05729.12 KND96890.1 - 1.3e-06 28.4 8.1 0.0014 18.6 3.6 4.0 3 1 0 3 3 3 2 NACHT domain AAA_22 PF13401.6 KND96890.1 - 3.1e-06 27.5 7.8 0.11 12.7 0.2 4.6 3 2 2 5 5 5 3 AAA domain AAA_18 PF13238.6 KND96890.1 - 5e-06 27.1 0.6 0.34 11.5 0.0 3.9 3 1 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 KND96890.1 - 1.3e-05 25.0 0.1 0.054 13.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.6 KND96890.1 - 3.5e-05 24.0 0.0 0.17 12.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KND96890.1 - 4.1e-05 23.4 0.0 0.18 11.5 0.0 2.8 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 KND96890.1 - 4.3e-05 23.2 2.4 0.66 9.5 0.1 3.9 2 2 1 4 4 4 1 AAA domain AAA_14 PF13173.6 KND96890.1 - 7.7e-05 22.7 0.1 0.76 9.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 KND96890.1 - 0.00013 22.3 0.1 1.4 9.3 0.0 3.3 3 0 0 3 3 2 2 RNA helicase AAA_2 PF07724.14 KND96890.1 - 0.00015 22.0 0.0 0.013 15.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) NB-ARC PF00931.22 KND96890.1 - 0.00032 20.0 0.2 0.15 11.3 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain TsaE PF02367.17 KND96890.1 - 0.00034 20.6 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KND96890.1 - 0.0004 20.4 0.0 1.1 9.3 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KND96890.1 - 0.00099 18.9 0.0 0.019 14.7 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KND96890.1 - 0.0013 18.5 0.1 0.97 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KND96890.1 - 0.0051 16.2 0.1 0.57 9.5 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KND96890.1 - 0.0074 15.5 0.0 0.27 10.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TIP49 PF06068.13 KND96890.1 - 0.0078 15.5 0.0 0.3 10.3 0.0 2.4 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_17 PF13207.6 KND96890.1 - 0.013 15.9 2.5 1.9 8.9 0.1 2.9 3 0 0 3 3 2 0 AAA domain Sigma54_activat PF00158.26 KND96890.1 - 0.017 14.8 0.0 7.8 6.2 0.0 3.1 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 KND96890.1 - 0.022 14.3 1.1 1.7 8.2 0.0 3.1 3 0 0 3 3 3 0 P-loop containing dynein motor region ATPase PF06745.13 KND96890.1 - 0.024 14.0 0.0 4.5 6.5 0.0 2.5 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.6 KND96890.1 - 0.034 14.4 0.0 5.4 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KND96890.1 - 0.039 13.7 0.1 0.81 9.5 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF2075 PF09848.9 KND96890.1 - 0.043 13.1 0.0 5.3 6.2 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Torsin PF06309.11 KND96890.1 - 0.045 13.9 0.1 0.64 10.1 0.0 2.5 2 0 0 2 2 2 0 Torsin Zeta_toxin PF06414.12 KND96890.1 - 0.13 11.5 0.3 5.1 6.3 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 KND96890.1 - 0.3 11.0 8.4 0.59 10.0 0.0 4.1 4 2 1 5 5 4 0 ATPase domain predominantly from Archaea DUF3767 PF12597.8 KND96891.1 - 4.3e-34 116.4 0.1 5.9e-34 115.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) CPP1-like PF11833.8 KND96891.1 - 0.31 10.7 1.7 0.47 10.1 0.5 1.9 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like EMC3_TMCO1 PF01956.16 KND96892.1 - 3.2e-08 33.5 0.0 3.2e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like EMC3_TMCO1 PF01956.16 KND96893.1 - 1.3e-30 106.4 2.5 1.7e-30 106.0 2.5 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like ATP_bind_1 PF03029.17 KND96894.1 - 1.3e-78 264.2 0.2 2.3e-78 263.3 0.2 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KND96894.1 - 5e-09 36.0 0.2 9.2e-08 31.9 0.2 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 KND96894.1 - 2.4e-06 27.4 0.1 9.8e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KND96894.1 - 7.1e-06 25.2 0.0 0.04 12.9 0.0 2.8 2 1 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 KND96894.1 - 3.7e-05 23.3 0.1 0.042 13.3 0.0 3.5 2 2 0 2 2 2 1 ADP-ribosylation factor family AAA_22 PF13401.6 KND96894.1 - 0.00012 22.4 0.3 0.00055 20.2 0.0 2.3 3 1 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.23 KND96894.1 - 0.0002 21.4 0.0 0.0052 16.8 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KND96894.1 - 0.0003 21.0 0.1 0.00084 19.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain RsgA_GTPase PF03193.16 KND96894.1 - 0.00058 19.8 0.2 2.2 8.1 0.0 3.3 3 1 1 4 4 4 2 RsgA GTPase FeoB_N PF02421.18 KND96894.1 - 0.0006 19.4 0.0 0.027 14.0 0.0 2.7 2 1 0 2 2 2 1 Ferrous iron transport protein B NACHT PF05729.12 KND96894.1 - 0.0021 18.0 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain SRP54 PF00448.22 KND96894.1 - 0.0022 17.7 0.0 0.018 14.7 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_18 PF13238.6 KND96894.1 - 0.0035 17.9 0.8 0.037 14.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain G-alpha PF00503.20 KND96894.1 - 0.0051 16.0 1.2 0.053 12.7 0.0 2.8 3 0 0 3 3 3 1 G-protein alpha subunit PduV-EutP PF10662.9 KND96894.1 - 0.0052 16.5 0.1 0.13 12.0 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 KND96894.1 - 0.0089 15.8 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 KND96894.1 - 0.012 15.0 0.0 0.75 9.2 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Zeta_toxin PF06414.12 KND96894.1 - 0.014 14.7 0.0 0.036 13.3 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 KND96894.1 - 0.014 15.8 0.0 0.049 14.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 KND96894.1 - 0.015 14.5 0.0 0.028 13.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 KND96894.1 - 0.017 14.6 0.0 0.064 12.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 KND96894.1 - 0.019 15.1 0.3 2 8.4 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Roc PF08477.13 KND96894.1 - 0.022 15.0 0.0 1.1 9.5 0.0 2.6 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase APS_kinase PF01583.20 KND96894.1 - 0.024 14.5 0.0 0.049 13.5 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_19 PF13245.6 KND96894.1 - 0.026 14.8 0.0 0.37 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 KND96894.1 - 0.031 14.1 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Viral_helicase1 PF01443.18 KND96894.1 - 0.06 13.1 0.1 0.83 9.3 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.14 KND96894.1 - 0.065 12.5 0.1 0.18 11.0 0.1 1.9 1 1 0 1 1 1 0 KAP family P-loop domain RNA_helicase PF00910.22 KND96894.1 - 0.077 13.4 0.2 0.8 10.1 0.0 2.7 3 0 0 3 3 3 0 RNA helicase cobW PF02492.19 KND96894.1 - 0.079 12.5 0.1 1.4 8.5 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GLTSCR1 PF15249.6 KND96894.1 - 0.13 12.7 4.2 0.23 11.9 0.2 2.7 2 0 0 2 2 2 0 Conserved region of unknown function on GLTSCR protein Thymidylate_kin PF02223.17 KND96894.1 - 0.37 10.5 0.0 0.37 10.5 0.0 2.5 4 0 0 4 4 3 0 Thymidylate kinase Glyco_hydro_125 PF06824.11 KND96895.1 - 5e-169 562.6 0.0 5.9e-169 562.4 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) TSC22 PF01166.18 KND96896.1 - 0.039 14.3 1.0 14 6.1 0.1 2.8 2 0 0 2 2 2 0 TSC-22/dip/bun family Methyltransf_16 PF10294.9 KND96897.1 - 6.1e-12 45.6 0.0 1.4e-10 41.2 0.0 2.0 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 KND96897.1 - 0.13 13.0 0.0 0.24 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Antimicrobial_1 PF08018.11 KND96897.1 - 0.51 10.5 2.1 1.1 9.4 2.1 1.5 1 0 0 1 1 1 0 Frog antimicrobial peptide DUF202 PF02656.15 KND96898.1 - 2.8e-21 75.7 4.8 7.1e-21 74.4 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SLATT_5 PF18160.1 KND96898.1 - 0.023 14.0 3.7 3.6 6.9 4.4 2.1 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Phage_holin_3_6 PF07332.11 KND96898.1 - 0.03 14.4 3.3 0.041 13.9 3.3 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III TRIQK PF15168.6 KND96898.1 - 0.15 12.0 6.6 0.27 11.2 0.5 2.3 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family DUF3784 PF12650.7 KND96898.1 - 0.17 12.1 6.6 0.3 11.3 6.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) KRE1 PF17056.5 KND96900.1 - 1.9e-19 69.1 11.9 2e-19 69.0 10.9 1.6 1 1 0 1 1 1 1 Killer toxin-resistance protein 1 Coa1 PF08695.10 KND96900.1 - 0.58 9.9 3.6 2.9 7.7 0.1 2.4 1 1 1 2 2 2 0 Cytochrome oxidase complex assembly protein 1 Mucin PF01456.17 KND96900.1 - 7.3 6.6 15.9 9 6.3 15.9 1.3 1 1 0 1 1 1 0 Mucin-like glycoprotein Metallophos PF00149.28 KND96902.1 - 0.0048 17.4 0.0 0.0077 16.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MCM PF00493.23 KND96903.1 - 2.6e-98 327.6 0.0 3.8e-98 327.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM2_N PF12619.8 KND96903.1 - 1.5e-43 148.7 32.2 1.5e-43 148.7 32.2 3.0 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_OB PF17207.3 KND96903.1 - 6.4e-38 129.4 0.1 1.2e-37 128.6 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KND96903.1 - 7.1e-26 90.5 0.3 1.7e-25 89.3 0.3 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KND96903.1 - 4.4e-11 43.3 1.2 1.1e-10 42.0 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KND96903.1 - 3.7e-08 33.0 0.0 2.5e-06 27.1 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KND96903.1 - 8.6e-07 29.0 0.0 2.1e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KND96903.1 - 0.00034 20.5 0.0 0.0063 16.4 0.0 2.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KND96903.1 - 0.0032 17.2 0.1 0.017 14.8 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain zf-UBR PF02207.20 KND96904.1 - 2.6e-12 46.7 5.8 2.6e-12 46.7 5.8 1.9 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Lon_C PF05362.13 KND96905.1 - 8.2e-62 208.4 0.0 1.8e-61 207.3 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KND96905.1 - 2.8e-23 82.9 4.6 3e-23 82.8 0.1 2.5 1 1 1 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KND96905.1 - 3.9e-21 75.9 1.1 2.6e-20 73.2 0.0 2.6 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KND96905.1 - 1.6e-07 31.4 0.0 5.1e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 KND96905.1 - 8.7e-07 28.2 0.1 7.4e-06 25.1 0.0 2.1 2 0 0 2 2 2 1 PrkA AAA domain RuvB_N PF05496.12 KND96905.1 - 1.3e-05 25.0 0.0 0.00038 20.2 0.0 2.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KND96905.1 - 1.7e-05 25.0 0.0 6.4e-05 23.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KND96905.1 - 2e-05 25.1 0.1 9e-05 22.9 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KND96905.1 - 3.8e-05 24.0 1.0 0.0027 18.0 0.1 2.8 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 KND96905.1 - 0.00017 21.4 0.0 0.00037 20.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein NTPase_1 PF03266.15 KND96905.1 - 0.00021 21.2 0.1 0.006 16.5 0.0 2.4 1 1 1 2 2 2 1 NTPase AAA_18 PF13238.6 KND96905.1 - 0.0004 20.9 0.0 0.0036 17.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain ChlI PF13541.6 KND96905.1 - 0.0019 18.1 0.0 0.0045 16.8 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase TIP49 PF06068.13 KND96905.1 - 0.0022 17.3 0.1 0.0042 16.3 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 KND96905.1 - 0.0037 17.3 0.3 0.012 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KND96905.1 - 0.0047 16.7 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KND96905.1 - 0.0094 16.3 2.0 0.029 14.7 0.1 2.4 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KND96905.1 - 0.013 15.4 0.0 0.13 12.2 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 KND96905.1 - 0.016 14.6 0.0 0.27 10.6 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KND96905.1 - 0.025 14.6 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Exonuc_VII_L PF02601.15 KND96905.1 - 0.026 14.1 2.2 0.046 13.3 2.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_28 PF13521.6 KND96905.1 - 0.027 14.7 0.0 0.088 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KND96905.1 - 0.029 13.5 0.0 0.071 12.2 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 KND96905.1 - 0.036 13.6 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KND96905.1 - 0.039 14.1 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 KND96905.1 - 0.041 13.7 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KND96905.1 - 0.048 12.9 0.1 0.13 11.5 0.1 1.7 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 KND96905.1 - 0.055 13.9 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KND96905.1 - 0.077 12.7 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KND96905.1 - 0.094 12.4 0.0 0.29 10.8 0.0 1.9 1 0 0 1 1 1 0 Cytidylate kinase DUF2956 PF11169.8 KND96905.1 - 0.14 12.4 3.0 0.6 10.3 3.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Rad17 PF03215.15 KND96905.1 - 0.16 11.9 1.7 1.5 8.7 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain ABC_tran PF00005.27 KND96905.1 - 0.22 12.1 0.1 0.22 12.1 0.1 2.8 2 1 0 2 2 2 0 ABC transporter AAA_11 PF13086.6 KND96905.1 - 0.46 10.2 0.0 0.46 10.2 0.0 3.1 4 0 0 4 4 3 0 AAA domain Pox_A_type_inc PF04508.12 KND96906.1 - 0.0081 16.0 3.2 1.5 8.8 0.2 3.6 3 0 0 3 3 3 1 Viral A-type inclusion protein repeat DUF4404 PF14357.6 KND96906.1 - 0.023 15.3 0.5 0.083 13.5 0.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) TSC22 PF01166.18 KND96906.1 - 0.85 10.0 4.4 3.7 7.9 0.1 2.9 2 1 1 3 3 3 0 TSC-22/dip/bun family UAF_Rrn10 PF05234.11 KND96907.1 - 1.9e-05 24.9 0.2 6.6e-05 23.1 0.1 2.0 1 1 0 1 1 1 1 UAF complex subunit Rrn10 Methyltr_RsmB-F PF01189.17 KND96908.1 - 2.5e-38 131.8 0.0 9.7e-38 129.8 0.0 1.9 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KND96908.1 - 8.6e-05 22.7 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase zf-RING_2 PF13639.6 KND96909.1 - 1.2e-11 44.7 5.6 2.2e-11 43.9 5.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KND96909.1 - 4.8e-10 39.1 4.6 9.1e-10 38.2 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KND96909.1 - 6.1e-09 36.0 3.2 1.3e-08 35.0 3.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KND96909.1 - 2e-06 27.5 2.7 4e-06 26.6 2.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KND96909.1 - 4.4e-06 26.6 1.7 5.6e-06 26.3 0.9 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 KND96909.1 - 4.5e-06 26.3 0.9 1.3e-05 24.8 0.9 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KND96909.1 - 1.8e-05 24.5 4.0 3.2e-05 23.7 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KND96909.1 - 2.8e-05 23.9 4.0 4.3e-05 23.3 4.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KND96909.1 - 0.00011 22.1 1.8 0.0002 21.2 1.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KND96909.1 - 0.0019 18.2 1.1 0.0037 17.3 1.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H PF13771.6 KND96909.1 - 0.093 13.0 1.1 0.12 12.6 0.2 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain Zn_ribbon_17 PF17120.5 KND96909.1 - 0.11 12.1 2.8 0.22 11.2 2.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KND96909.1 - 0.17 11.7 2.4 0.64 9.9 2.4 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KND96909.1 - 0.21 11.8 4.9 1.8 8.8 4.9 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 KND96909.1 - 0.4 10.9 2.0 0.86 9.8 2.0 1.6 1 1 0 1 1 1 0 RING-variant domain CBFD_NFYB_HMF PF00808.23 KND96910.1 - 2.1e-25 88.8 0.1 4.1e-25 87.9 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KND96910.1 - 6e-05 23.4 1.8 0.00034 21.0 0.0 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KND96910.1 - 0.032 14.3 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KND96910.1 - 0.036 14.1 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Rft-1 PF04506.13 KND96911.1 - 3.6e-121 405.4 36.9 4.5e-121 405.1 36.9 1.0 1 0 0 1 1 1 1 Rft protein zf-C2H2_10 PF16588.5 KND96912.1 - 9e-09 34.9 6.5 9e-09 34.9 6.5 1.8 2 0 0 2 2 2 1 C2H2 zinc-finger C1_1 PF00130.22 KND96912.1 - 0.052 13.4 3.5 0.13 12.2 0.6 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Snapin_Pallidin PF14712.6 KND96912.1 - 0.053 13.9 0.6 0.053 13.9 0.6 1.7 2 0 0 2 2 2 0 Snapin/Pallidin DUF4211 PF13926.6 KND96912.1 - 0.076 13.1 1.3 0.15 12.1 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) YyzF PF14116.6 KND96912.1 - 0.17 11.9 0.6 0.75 9.9 0.0 2.2 2 0 0 2 2 2 0 YyzF-like protein HWE_HK PF07536.14 KND96912.1 - 0.19 12.4 1.1 0.94 10.2 0.4 2.2 1 1 1 2 2 2 0 HWE histidine kinase zf-CCHC_4 PF14392.6 KND96912.1 - 5.7 6.8 7.4 0.23 11.2 1.5 1.8 2 0 0 2 2 2 0 Zinc knuckle LSM PF01423.22 KND96913.1 - 1.3e-16 60.0 0.6 1.6e-16 59.7 0.6 1.1 1 0 0 1 1 1 1 LSM domain DUF1461 PF07314.11 KND96913.1 - 0.04 13.8 0.0 0.04 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) NDT80_PhoG PF05224.12 KND96914.1 - 5.2e-32 111.6 0.0 1.7e-31 109.9 0.0 1.8 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family GNAT_acetyltr_2 PF13718.6 KND96915.1 - 2.1e-99 331.6 0.0 7.9e-99 329.7 0.0 2.1 2 0 0 2 2 2 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KND96915.1 - 6.2e-89 297.7 5.7 1.2e-88 296.8 5.7 1.5 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KND96915.1 - 1.5e-65 220.4 0.0 1.4e-64 217.2 0.0 2.5 2 1 0 2 2 2 1 Helicase DUF1726 PF08351.11 KND96915.1 - 4.9e-34 116.2 0.5 1.6e-33 114.5 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KND96915.1 - 0.0017 18.1 0.0 0.045 13.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KND96915.1 - 0.0038 17.5 0.0 0.49 10.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KND96915.1 - 0.011 16.0 0.0 0.1 13.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Acetyltransf_1 PF00583.25 KND96915.1 - 0.053 13.7 0.0 0.22 11.8 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KND96915.1 - 0.097 13.1 0.0 0.55 10.7 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PRK PF00485.18 KND96916.1 - 2.9e-08 33.7 0.0 7.6e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KND96916.1 - 5.9e-05 23.6 0.0 0.00015 22.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain CPT PF07931.12 KND96916.1 - 0.0021 17.9 0.0 0.0046 16.8 0.0 1.9 1 1 1 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 KND96916.1 - 0.0026 18.1 0.0 0.0042 17.5 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KND96916.1 - 0.0083 16.4 0.6 0.036 14.3 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 KND96916.1 - 0.0092 15.7 0.0 0.02 14.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KND96916.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_17 PF13207.6 KND96916.1 - 0.042 14.3 0.1 6.8 7.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 KND96916.1 - 0.051 14.1 0.4 0.28 11.6 0.0 2.2 2 1 0 3 3 3 0 AAA domain KTI12 PF08433.10 KND96916.1 - 0.069 12.6 0.0 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_21 PF13304.6 KND96916.1 - 0.088 12.6 0.1 0.13 12.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 KND96916.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 KND96916.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF2722 PF10846.8 KND96918.1 - 5e-17 62.0 17.1 9.2e-13 47.9 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) Presenilin PF01080.17 KND96918.1 - 1.2 7.8 5.7 2.2 6.9 5.7 1.3 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 KND96918.1 - 1.4 7.1 12.6 2.2 6.5 12.6 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 KND96918.1 - 5.5 6.9 34.7 0.27 11.2 27.0 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 KND96918.1 - 7.1 6.5 16.0 0.25 11.3 9.7 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4630 PF15443.6 KND96919.1 - 0.24 11.6 0.1 0.25 11.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) AA_permease_2 PF13520.6 KND96920.1 - 8e-67 225.9 40.0 9.4e-67 225.7 40.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KND96920.1 - 6.7e-14 51.3 33.6 1.1e-13 50.7 33.6 1.3 1 0 0 1 1 1 1 Amino acid permease Phage_holin_2_4 PF16082.5 KND96920.1 - 3.9 7.3 5.3 2.1 8.1 0.4 2.9 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like MFS_1 PF07690.16 KND96921.1 - 1.5e-34 119.5 34.7 1.7e-30 106.2 20.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND96921.1 - 7.6e-09 34.9 10.7 7.6e-09 34.9 10.7 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 KND96921.1 - 0.11 10.7 17.2 0.023 13.0 1.1 3.0 3 1 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Snf7 PF03357.21 KND96922.1 - 7.5e-44 149.4 11.7 8.8e-44 149.1 11.7 1.0 1 0 0 1 1 1 1 Snf7 Seryl_tRNA_N PF02403.22 KND96922.1 - 0.0029 17.8 12.5 0.011 16.0 3.4 2.4 3 0 0 3 3 3 2 Seryl-tRNA synthetase N-terminal domain Prefoldin_2 PF01920.20 KND96922.1 - 0.0095 15.9 14.4 0.27 11.2 0.0 3.3 2 1 0 2 2 2 1 Prefoldin subunit DUF2120 PF09893.9 KND96922.1 - 0.015 15.4 1.6 0.015 15.4 1.6 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DUF1411 PF07199.11 KND96922.1 - 0.025 14.2 0.8 0.036 13.7 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1411) Exonuc_VII_L PF02601.15 KND96922.1 - 0.11 12.0 4.4 0.15 11.6 4.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit PRESAN PF09687.10 KND96922.1 - 0.12 12.9 6.0 1.7 9.2 0.0 2.5 1 1 1 2 2 2 0 Plasmodium RESA N-terminal FlaC_arch PF05377.11 KND96922.1 - 0.25 11.8 11.4 0.33 11.4 0.2 4.0 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) DUF1319 PF07028.11 KND96922.1 - 0.56 10.4 7.8 0.15 12.3 2.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) DUF5344 PF17279.2 KND96922.1 - 0.89 10.2 12.6 3.7 8.2 7.0 2.9 2 2 0 2 2 2 0 Family of unknown function (DUF5344) NPV_P10 PF05531.12 KND96922.1 - 1 9.8 11.7 1.9 9.0 0.1 3.4 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein LRRFIP PF09738.9 KND96922.1 - 1.3 8.4 13.4 0.5 9.8 8.0 2.5 1 1 1 2 2 2 0 LRRFIP family Atg14 PF10186.9 KND96922.1 - 1.4 7.9 10.8 7.5 5.5 10.8 1.9 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 KND96922.1 - 1.5 9.5 12.4 15 6.3 0.5 3.8 1 1 1 3 3 3 0 SlyX FapA PF03961.13 KND96922.1 - 2.5 6.6 12.3 1.3 7.5 8.5 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A ZapB PF06005.12 KND96922.1 - 3.9 8.0 16.5 5.6 7.5 4.4 2.9 2 1 1 3 3 3 0 Cell division protein ZapB Fib_alpha PF08702.10 KND96922.1 - 8.3 6.6 14.7 19 5.4 0.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Cupin_5 PF06172.11 KND96924.1 - 0.1 12.8 0.0 0.1 12.8 0.0 1.0 1 0 0 1 1 1 0 Cupin superfamily (DUF985) MFS_1 PF07690.16 KND96927.1 - 5.6e-38 130.8 17.8 5.6e-38 130.8 17.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND96927.1 - 3.9e-09 35.9 18.9 6e-09 35.3 18.6 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4710 PF15828.5 KND96929.1 - 2.7 8.2 12.4 2.6 8.2 10.4 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4710) Hyr1 PF15789.5 KND96933.1 - 2.1e-65 216.0 395.2 2.8e-07 29.9 12.9 22.8 21 3 1 22 22 22 18 Hyphally regulated cell wall GPI-anchored protein 1 Imm53 PF15580.6 KND96933.1 - 8.4e-12 44.6 42.5 10 5.9 0.1 16.7 18 0 0 18 18 18 3 Immunity protein 53 LpxD PF04613.14 KND96933.1 - 2.3e-10 40.1 3.7 3.3 7.6 0.0 12.9 18 0 0 18 18 18 1 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD DUF3872 PF12988.7 KND96933.1 - 2.8e-09 36.9 0.3 37 4.2 0.0 10.7 4 2 2 11 11 11 0 Domain of unknown function, B. Theta Gene description (DUF3872) FTP PF07504.13 KND96933.1 - 1.7e-06 27.7 63.2 1.4 8.8 0.2 18.6 18 1 0 18 18 18 3 Fungalysin/Thermolysin Propeptide Motif PPV_E2_C PF00511.17 KND96933.1 - 7.8e-06 26.0 96.8 2.4 8.4 0.2 17.8 2 2 15 18 18 18 6 E2 (early) protein, C terminal RNase_P_pop3 PF08228.11 KND96933.1 - 0.00079 19.5 1.9 1.8e+02 2.1 0.0 7.3 8 0 0 8 8 8 0 RNase P subunit Pop3 DUF2888 PF11135.8 KND96933.1 - 0.063 13.2 86.9 3.3 7.7 0.1 16.7 4 2 13 18 18 18 0 Protein of unknown function (DUF2888) FlgD_ig PF13860.6 KND96933.1 - 0.15 11.9 99.3 1.1 9.2 0.7 16.4 3 2 15 18 18 18 0 FlgD Ig-like domain Mannosyl_trans3 PF11051.8 KND96934.1 - 2e-63 214.3 0.0 2.7e-63 213.9 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Amidase PF01425.21 KND96935.1 - 1.1e-98 331.1 0.0 2.7e-98 329.9 0.0 1.5 1 1 0 1 1 1 1 Amidase UPF0180 PF03698.13 KND96935.1 - 0.097 12.9 0.0 0.34 11.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) SSF PF00474.17 KND96936.1 - 2.5e-19 69.4 25.1 2.5e-19 69.4 25.1 2.2 2 0 0 2 2 2 1 Sodium:solute symporter family Asp PF00026.23 KND96937.1 - 1.3e-66 225.2 2.3 1.5e-66 225.0 2.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KND96937.1 - 5e-07 30.1 2.3 0.0011 19.3 0.1 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 KND96937.1 - 0.0022 18.5 0.0 2.6 8.7 0.0 3.7 2 2 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KND96937.1 - 0.0036 17.9 0.0 12 6.7 0.0 3.7 2 2 0 2 2 2 2 Aspartyl protease DUF3912 PF13051.6 KND96937.1 - 0.1 12.9 0.1 0.44 10.8 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3912) p450 PF00067.22 KND96940.1 - 1.4e-45 155.9 0.0 1.8e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GP70 PF17429.2 KND96940.1 - 0.061 13.2 0.1 19 5.2 0.0 2.7 3 0 0 3 3 3 0 Gene product 70 Amidohydro_1 PF01979.20 KND96942.1 - 1.9e-62 211.6 0.0 2.4e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KND96942.1 - 1.2e-08 34.9 0.0 1.3e-06 28.1 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase family Fungal_trans_2 PF11951.8 KND96943.1 - 2.3e-20 72.8 3.0 7.7e-20 71.0 3.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Amidase PF01425.21 KND96945.1 - 2.5e-91 306.9 0.0 4.3e-91 306.1 0.0 1.4 1 1 0 1 1 1 1 Amidase CLP1_P PF16575.5 KND96946.1 - 9.8e-23 80.9 0.0 2.2e-22 79.8 0.0 1.7 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Lectin_leg-like PF03388.13 KND96948.1 - 8e-14 51.5 0.1 1.2e-13 50.9 0.1 1.2 1 0 0 1 1 1 1 Legume-like lectin family MscS_TM PF12794.7 KND96948.1 - 0.18 10.6 4.7 3.9 6.2 1.0 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 SpecificRecomb PF10136.9 KND96948.1 - 0.3 9.4 2.9 0.43 8.8 2.9 1.1 1 0 0 1 1 1 0 Site-specific recombinase HIP1_clath_bdg PF16515.5 KND96948.1 - 0.62 10.7 9.7 6 7.5 0.5 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 muHD PF10291.9 KND96949.1 - 4.2e-50 170.6 0.1 6.9e-50 169.9 0.1 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Adap_comp_sub PF00928.21 KND96949.1 - 0.092 12.1 1.5 0.25 10.7 0.3 2.2 2 1 0 2 2 2 0 Adaptor complexes medium subunit family TFIID-31kDa PF02291.15 KND96949.1 - 0.13 12.4 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Ammonium_transp PF00909.21 KND96951.1 - 6.5e-92 308.3 19.2 7.4e-92 308.1 19.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Tetraspanin PF00335.20 KND96951.1 - 0.071 12.8 0.6 0.14 11.9 0.6 1.4 1 0 0 1 1 1 0 Tetraspanin family UPF0183 PF03676.14 KND96953.1 - 4.5e-54 184.3 0.0 2.9e-53 181.6 0.0 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) LRR_9 PF14580.6 KND96954.1 - 1.4e-31 109.3 3.4 2e-31 108.8 3.4 1.2 1 0 0 1 1 1 1 Leucine-rich repeat Paramyx_P_V_C PF03210.13 KND96954.1 - 0.00056 19.7 2.0 0.18 11.6 0.2 2.2 2 0 0 2 2 2 2 Paramyxovirus P/V phosphoprotein C-terminal UPF0160 PF03690.13 KND96954.1 - 0.059 13.0 0.1 4.8 6.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0160) LRR_4 PF12799.7 KND96954.1 - 0.062 13.7 17.8 0.077 13.4 3.1 4.0 2 2 2 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KND96954.1 - 0.16 11.7 14.3 0.049 13.4 8.1 3.0 1 1 1 2 2 2 0 Leucine rich repeat PHD PF00628.29 KND96955.1 - 4.2e-13 49.0 28.3 5.5e-08 32.6 9.2 6.6 8 1 0 8 8 8 3 PHD-finger BAH PF01426.18 KND96955.1 - 7.4e-12 45.2 2.1 1.1e-11 44.7 0.0 2.3 3 0 0 3 3 3 1 BAH domain PHD_2 PF13831.6 KND96955.1 - 2.5e-09 36.6 13.6 7.9e-07 28.5 3.4 4.2 3 0 0 3 3 3 2 PHD-finger zf-HC5HC2H PF13771.6 KND96955.1 - 4.4e-06 26.8 2.6 4.4e-06 26.8 2.6 6.1 6 1 1 7 7 7 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KND96955.1 - 0.00014 22.0 8.5 0.00014 22.0 8.5 5.6 4 2 0 4 4 4 2 PHD-zinc-finger like domain mRNA_cap_enzyme PF01331.19 KND96956.1 - 1.9e-56 191.0 0.0 2.8e-56 190.4 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KND96956.1 - 1.9e-32 112.1 0.7 3.7e-32 111.2 0.2 1.8 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KND96956.1 - 2.9e-07 30.4 0.0 0.024 14.3 0.0 2.5 1 1 1 2 2 2 2 ATP dependent DNA ligase domain SelP_N PF04592.14 KND96956.1 - 3.1 7.1 11.0 5.7 6.3 11.0 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Prefoldin_2 PF01920.20 KND96957.1 - 2.2e-19 69.4 10.1 2.5e-19 69.2 10.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit DivIC PF04977.15 KND96957.1 - 9.8e-05 22.1 8.0 0.0081 15.9 1.8 2.2 2 0 0 2 2 2 2 Septum formation initiator FliD_C PF07195.12 KND96957.1 - 0.029 13.8 1.8 0.036 13.5 0.3 1.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus HALZ PF02183.18 KND96957.1 - 0.074 13.3 7.4 0.21 11.8 0.3 2.7 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF4600 PF15372.6 KND96957.1 - 0.15 12.5 6.3 2.2 8.8 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) Prefoldin PF02996.17 KND96957.1 - 0.19 11.6 7.9 1.4 8.8 7.9 2.0 1 1 0 1 1 1 0 Prefoldin subunit NPV_P10 PF05531.12 KND96957.1 - 0.23 11.9 3.4 8.2 7.0 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 KND96957.1 - 0.25 11.7 4.4 0.51 10.8 0.2 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.6 KND96957.1 - 0.38 11.2 5.0 23 5.5 5.0 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) bZIP_1 PF00170.21 KND96957.1 - 0.43 10.7 7.0 2.1 8.5 0.1 2.8 2 1 1 3 3 3 0 bZIP transcription factor Med4 PF10018.9 KND96957.1 - 0.88 9.2 6.2 0.26 11.0 2.0 1.9 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 TSC22 PF01166.18 KND96957.1 - 2.3 8.6 7.1 1.6 9.1 0.1 2.8 2 1 1 3 3 3 0 TSC-22/dip/bun family FlxA PF14282.6 KND96957.1 - 3.1 7.8 6.9 0.98 9.4 0.3 2.2 2 0 0 2 2 2 0 FlxA-like protein Acetyltransf_9 PF13527.7 KND96958.1 - 2e-05 24.7 0.1 5.3e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KND96958.1 - 9.9e-05 22.7 0.0 0.00085 19.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KND96958.1 - 0.001 19.3 0.0 0.06 13.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KND96958.1 - 0.017 15.1 0.0 0.043 13.8 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 KND96958.1 - 0.12 12.5 0.0 0.57 10.4 0.0 2.1 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase DUF5549 PF17703.1 KND96961.1 - 0.072 12.7 2.6 0.074 12.7 2.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5549) Homeobox_KN PF05920.11 KND96962.1 - 9.3e-19 67.1 1.5 1.7e-18 66.2 1.5 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KND96962.1 - 1.1e-05 25.1 1.1 1.8e-05 24.4 1.1 1.4 1 0 0 1 1 1 1 Homeodomain Exo70 PF03081.15 KND96964.1 - 2.1e-58 198.2 3.1 2.1e-58 198.2 3.1 1.8 2 1 0 2 2 2 1 Exo70 exocyst complex subunit COG6 PF06419.11 KND96964.1 - 3.2e-05 22.4 5.0 0.0088 14.3 0.4 2.4 2 0 0 2 2 2 2 Conserved oligomeric complex COG6 Sec34 PF04136.15 KND96964.1 - 0.021 14.7 0.5 0.021 14.7 0.5 2.6 2 0 0 2 2 2 0 Sec34-like family RNA_lig_T4_1 PF09511.10 KND96965.1 - 6.8e-71 238.6 0.7 1.6e-70 237.4 0.7 1.7 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 KND96965.1 - 2.8e-39 134.9 0.1 2.1e-38 132.1 0.0 2.4 2 0 0 2 2 2 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 KND96965.1 - 1.3e-23 83.8 0.8 6.2e-23 81.5 0.8 2.0 1 1 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_22 PF13401.6 KND96965.1 - 0.057 13.7 0.0 0.19 12.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain tRNA_lig_kinase PF08303.11 KND96966.1 - 2.8e-27 95.8 0.4 5.1e-27 95.0 0.4 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain Tenui_N PF05733.11 KND96966.1 - 0.042 13.4 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 Tenuivirus/Phlebovirus nucleocapsid protein Fumble PF03630.14 KND96969.1 - 5.2e-124 413.7 0.6 6.3e-124 413.4 0.6 1.1 1 0 0 1 1 1 1 Fumble DUF2181 PF10223.9 KND96969.1 - 0.09 12.2 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2181) PEX11 PF05648.14 KND96970.1 - 1.1e-08 34.9 1.4 0.00033 20.2 0.4 2.3 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) PALP PF00291.25 KND96971.1 - 1.1e-60 205.6 0.0 1.3e-60 205.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FdhE PF04216.12 KND96973.1 - 0.19 11.6 2.5 0.22 11.4 2.5 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation ING PF12998.7 KND96974.1 - 1.9e-22 79.8 7.5 3.1e-22 79.1 7.5 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KND96974.1 - 2.1e-06 27.5 8.1 3.5e-06 26.8 8.1 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KND96974.1 - 0.036 13.6 2.4 0.063 12.8 2.4 1.4 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 KND96974.1 - 0.037 14.3 0.2 0.037 14.3 0.2 1.7 2 0 0 2 2 2 0 PHD-like zinc-binding domain Terminase_4 PF05119.12 KND96974.1 - 0.15 12.5 1.2 1.3 9.5 0.4 2.2 2 0 0 2 2 2 0 Phage terminase, small subunit zf-C4_Topoisom PF01396.19 KND96974.1 - 0.99 9.2 6.3 3.2 7.6 0.9 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger PhnA_Zn_Ribbon PF08274.12 KND96974.1 - 1 9.3 4.8 2.2 8.3 0.3 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Fungal_trans PF04082.18 KND96979.1 - 7.2e-28 97.4 0.1 1.8e-27 96.1 0.0 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND96979.1 - 2.8e-09 36.9 9.6 4.5e-09 36.3 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5102 PF17104.5 KND96980.1 - 4.4e-23 82.8 8.1 9e-23 81.7 8.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF5102) Pept_tRNA_hydro PF01195.19 KND96981.1 - 4.4e-31 108.1 0.1 5.4e-31 107.8 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase DUF3336 PF11815.8 KND96982.1 - 1.7e-48 163.8 4.5 3.6e-48 162.8 4.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KND96982.1 - 7.5e-15 55.6 0.1 4.9e-14 53.0 0.0 2.4 2 1 0 2 2 2 1 Patatin-like phospholipase BUD22 PF09073.10 KND96982.1 - 0.052 12.9 3.2 0.092 12.1 3.2 1.3 1 0 0 1 1 1 0 BUD22 E1_dh PF00676.20 KND96983.1 - 0.08 11.9 0.0 0.094 11.6 0.0 1.1 1 0 0 1 1 1 0 Dehydrogenase E1 component UBA PF00627.31 KND96986.1 - 2.9e-25 87.7 5.4 8.7e-13 47.9 0.6 2.7 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 KND96986.1 - 1.6e-16 59.7 0.9 1.6e-16 59.7 0.9 1.7 2 0 0 2 2 2 1 XPC-binding domain WIYLD PF10440.9 KND96986.1 - 0.007 16.1 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-binding WIYLD domain UBA_3 PF09288.10 KND96986.1 - 0.033 14.0 0.0 2 8.3 0.0 2.3 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain TetR_C_28 PF17937.1 KND96986.1 - 0.05 14.0 0.7 0.12 12.8 0.2 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF3306 PF11748.8 KND96986.1 - 2 9.3 13.9 0.95 10.3 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) DUF3020 PF11223.8 KND96987.1 - 4.4e-21 75.1 10.9 4.4e-21 75.1 10.9 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3020) Creatinase_N_2 PF16189.5 KND96988.1 - 5.7e-37 127.3 0.5 1.5e-35 122.7 0.2 2.3 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KND96988.1 - 1.4e-32 113.1 0.0 2e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KND96988.1 - 2.2e-15 56.5 0.0 5e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KND96988.1 - 2.7e-12 47.5 0.0 8e-10 39.5 0.0 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain SMC_N PF02463.19 KND96989.1 - 1.3e-64 217.7 0.0 4.5e-64 215.9 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KND96989.1 - 7.3e-26 90.8 0.3 4.5e-25 88.2 0.3 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KND96989.1 - 1.3e-12 48.2 4.5 5.3e-08 33.0 2.0 4.1 3 1 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KND96989.1 - 1.9e-07 31.8 30.0 1.9e-07 31.8 30.0 6.8 3 2 2 5 5 4 2 AAA domain AAA_29 PF13555.6 KND96989.1 - 3.1e-07 30.0 0.1 6.4e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tropomyosin_1 PF12718.7 KND96989.1 - 0.0051 17.0 9.6 0.0051 17.0 9.6 7.2 6 2 1 7 7 7 2 Tropomyosin like TPR_MLP1_2 PF07926.12 KND96989.1 - 0.0072 16.4 8.9 0.0072 16.4 8.9 8.0 6 3 0 7 7 7 1 TPR/MLP1/MLP2-like protein AAA_27 PF13514.6 KND96989.1 - 0.024 14.2 0.1 0.024 14.2 0.1 4.6 5 0 0 5 5 5 0 AAA domain ABC_tran PF00005.27 KND96989.1 - 0.13 12.8 0.1 0.13 12.8 0.1 5.4 4 3 0 4 4 2 0 ABC transporter CSF-1 PF05337.11 KND96989.1 - 0.32 11.1 2.6 0.64 10.1 0.2 2.8 3 0 0 3 3 3 0 Macrophage colony stimulating factor-1 (CSF-1) DUF1664 PF07889.12 KND96989.1 - 1.1 9.3 47.7 0.019 15.0 1.5 7.8 6 3 4 10 10 10 0 Protein of unknown function (DUF1664) DUF2730 PF10805.8 KND96989.1 - 1.3 9.1 36.0 1.5 8.9 2.7 7.1 6 2 2 8 8 8 0 Protein of unknown function (DUF2730) DASH_Dam1 PF08653.10 KND96989.1 - 3.6 7.4 8.8 7.9 6.4 0.2 4.7 4 0 0 4 4 4 0 DASH complex subunit Dam1 ERM PF00769.19 KND96989.1 - 5 6.9 90.3 0.061 13.1 24.1 5.7 4 2 2 6 6 6 0 Ezrin/radixin/moesin family tRNA_U5-meth_tr PF05958.11 KND96990.1 - 1.1e-10 41.1 0.0 1.8e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 KND96990.1 - 0.0027 17.5 0.0 0.0092 15.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain TRAM PF01938.20 KND96990.1 - 0.021 14.8 0.2 0.1 12.6 0.0 2.1 2 0 0 2 2 2 0 TRAM domain MTS PF05175.14 KND96990.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 KND96990.1 - 0.13 13.0 0.0 0.31 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MA3 PF02847.17 KND96991.1 - 3.3e-22 78.6 0.5 4.9e-21 74.8 0.0 2.8 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 KND96991.1 - 3.8e-20 72.5 8.0 1.8e-18 67.0 6.6 2.5 2 0 0 2 2 2 2 MIF4G domain AAA PF00004.29 KND96992.1 - 1.8e-33 115.8 0.1 4e-33 114.6 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KND96992.1 - 7.2e-11 41.7 0.0 1.4e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_33 PF13671.6 KND96992.1 - 1.8e-05 24.9 0.0 4.6e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KND96992.1 - 2.5e-05 24.8 1.8 0.0023 18.3 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 KND96992.1 - 3.1e-05 23.8 0.0 7.7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KND96992.1 - 3.3e-05 24.1 0.0 9.9e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KND96992.1 - 5e-05 23.4 0.0 0.00014 21.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 KND96992.1 - 8.1e-05 23.0 0.5 0.39 11.0 0.0 2.6 3 0 0 3 3 3 2 Hydin Adenylate kinase-like domain AAA_22 PF13401.6 KND96992.1 - 0.00011 22.5 0.6 0.0059 16.9 0.2 3.1 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KND96992.1 - 0.00029 20.9 0.2 0.0019 18.2 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.6 KND96992.1 - 0.0012 19.0 0.0 0.0028 17.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.6 KND96992.1 - 0.0021 18.6 0.8 0.0085 16.6 0.0 2.3 2 1 0 3 3 2 1 AAA domain Mg_chelatase PF01078.21 KND96992.1 - 0.0022 17.4 0.1 0.0052 16.2 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KND96992.1 - 0.0031 17.4 0.6 0.015 15.2 0.1 2.2 2 0 0 2 2 2 1 NACHT domain Bac_DnaA PF00308.18 KND96992.1 - 0.0038 17.1 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Bacterial dnaA protein IstB_IS21 PF01695.17 KND96992.1 - 0.005 16.6 0.8 0.021 14.5 0.1 2.4 2 1 1 3 3 3 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KND96992.1 - 0.0057 17.0 0.1 0.016 15.6 0.0 1.8 2 0 0 2 2 1 1 RNA helicase Viral_helicase1 PF01443.18 KND96992.1 - 0.0063 16.3 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.17 KND96992.1 - 0.0076 15.4 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 TIP49 PF06068.13 KND96992.1 - 0.0096 15.2 0.1 0.023 13.9 0.1 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 KND96992.1 - 0.018 14.2 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TniB PF05621.11 KND96992.1 - 0.024 14.1 0.1 7.2 6.0 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein Rad17 PF03215.15 KND96992.1 - 0.024 14.6 0.4 0.11 12.4 0.1 2.2 1 1 0 2 2 2 0 Rad17 P-loop domain AAA_17 PF13207.6 KND96992.1 - 0.025 15.0 0.6 0.38 11.2 0.0 2.9 3 1 0 3 3 3 0 AAA domain NB-ARC PF00931.22 KND96992.1 - 0.031 13.5 0.5 0.082 12.1 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 KND96992.1 - 0.032 14.0 0.2 0.064 13.0 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 KND96992.1 - 0.036 13.6 0.1 0.15 11.5 0.1 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KND96992.1 - 0.041 14.4 0.0 0.12 12.9 0.0 2.0 1 1 0 1 1 1 0 ABC transporter TsaE PF02367.17 KND96992.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KND96992.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KND96992.1 - 0.14 11.9 2.3 1.4 8.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 KND96992.1 - 0.15 11.7 0.0 0.57 9.9 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA12 PF10443.9 KND96996.1 - 2.2e-149 498.0 10.2 6.6e-101 338.2 2.3 2.8 2 1 1 3 3 3 2 RNA12 protein RRM_1 PF00076.22 KND96996.1 - 1.5e-06 27.9 0.0 4.1e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.9 KND96996.1 - 0.00081 19.4 0.7 0.011 15.8 0.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2487) ATPase_2 PF01637.18 KND96996.1 - 1.1 9.2 8.8 0.58 10.0 1.0 3.0 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Peptidase_C48 PF02902.19 KND96997.1 - 3.3e-35 121.9 0.2 6.2e-35 121.0 0.2 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GidB PF02527.15 KND96997.1 - 0.037 13.3 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G TarS_C1 PF18674.1 KND96997.1 - 0.058 13.3 0.1 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 TarS beta-glycosyltransferase C-terminal domain 1 VTC PF09359.10 KND96999.1 - 2.4e-87 292.8 4.6 5.3e-87 291.7 4.6 1.6 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 KND96999.1 - 3.8e-10 40.1 4.3 3.8e-10 40.1 4.3 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 KND96999.1 - 2.5e-09 37.6 31.4 0.00098 19.1 0.8 4.4 3 2 1 4 4 4 3 SPX domain DUF4611 PF15387.6 KND96999.1 - 0.95 9.7 7.5 2.4 8.4 1.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Clat_adaptor_s PF01217.20 KND97000.1 - 1.9e-13 50.6 0.2 2.5e-13 50.2 0.2 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CwfJ_C_1 PF04677.15 KND97000.1 - 0.021 14.7 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Bromo_TP PF07524.13 KND97001.1 - 2.2e-05 24.4 0.0 4.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 KND97001.1 - 0.011 15.9 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 Histone-fold protein Cyclin_N PF00134.23 KND97002.1 - 6e-09 35.7 0.5 1.5e-08 34.4 0.5 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain DUF772 PF05598.11 KND97002.1 - 0.068 13.2 0.1 0.66 10.0 0.0 2.3 2 0 0 2 2 2 0 Transposase domain (DUF772) JAB PF01398.21 KND97004.1 - 4.7e-11 42.7 0.0 1.2e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KND97004.1 - 0.00088 19.7 3.5 0.0016 18.8 3.5 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF763 PF05559.11 KND97004.1 - 0.022 13.9 0.2 0.033 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Polysacc_deac_1 PF01522.21 KND97009.1 - 1.9e-13 50.4 0.0 2.6e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KND97009.1 - 4.4e-05 22.8 0.0 4.8e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF3261 PF11659.8 KND97009.1 - 0.35 10.7 1.6 0.58 10.0 1.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3261) FMN_red PF03358.15 KND97012.1 - 2e-08 34.2 0.0 3.4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KND97012.1 - 0.00021 21.1 0.0 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KND97012.1 - 0.00076 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 KND97012.1 - 0.01 16.1 0.2 10 6.4 0.0 2.8 3 0 0 3 3 3 0 Flavodoxin domain FMN_red PF03358.15 KND97013.1 - 2.8e-09 36.9 0.0 3.8e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 KND97013.1 - 0.0018 18.5 0.3 0.017 15.4 0.3 2.3 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.17 KND97013.1 - 0.002 17.9 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Sugar_tr PF00083.24 KND97014.1 - 3.1e-34 118.6 33.2 2.6e-19 69.4 11.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KND97014.1 - 1.4e-23 83.4 37.7 4.5e-13 48.8 22.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PTPRCAP PF15713.5 KND97016.1 - 0.0015 18.9 3.3 0.0018 18.6 3.3 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated Trypan_PARP PF05887.11 KND97016.1 - 0.002 18.1 21.6 0.002 18.1 21.6 1.6 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) RNA_pol_Rpc4 PF05132.14 KND97016.1 - 0.067 13.6 5.6 0.073 13.5 5.6 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2076 PF09849.9 KND97016.1 - 0.076 13.0 0.3 0.09 12.8 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Mitofilin PF09731.9 KND97016.1 - 0.096 11.5 8.4 0.11 11.3 8.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein RR_TM4-6 PF06459.12 KND97016.1 - 0.25 11.1 4.8 0.26 11.1 4.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 KND97016.1 - 0.78 9.1 3.7 0.96 8.9 3.7 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) ADH_zinc_N PF00107.26 KND97017.1 - 1.1e-23 83.6 0.4 2.7e-23 82.3 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KND97017.1 - 2.7e-18 65.8 0.0 5.6e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KND97017.1 - 1.5e-05 26.0 0.0 3.6e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF4795 PF16043.5 KND97018.1 - 0.07 12.7 0.3 0.077 12.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF2833 PF11090.8 KND97018.1 - 0.099 13.0 0.0 0.13 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) DNAP_B_exo_N PF08452.10 KND97018.1 - 0.82 9.1 4.3 0.43 10.0 0.7 2.2 2 0 0 2 2 2 0 DNA polymerase family B exonuclease domain, N-terminal LicD PF04991.13 KND97019.1 - 4.1e-21 76.2 4.8 3.8e-18 66.5 0.6 2.6 2 1 1 3 3 3 2 LicD family DUF3584 PF12128.8 KND97020.1 - 0.66 7.4 16.7 0.78 7.2 16.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PCM1_C PF15717.5 KND97020.1 - 2.8 6.5 19.7 3.6 6.2 19.7 1.0 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus Tn916-Xis PF09035.10 KND97021.1 - 0.16 12.2 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Excisionase from transposon Tn916 MFS_1 PF07690.16 KND97023.1 - 9.3e-46 156.4 49.2 2.7e-43 148.2 52.3 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KND97023.1 - 5.9e-16 58.0 28.0 7.6e-16 57.7 28.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KND97023.1 - 2.5e-08 33.2 19.3 2.5e-08 33.2 19.3 3.5 2 1 0 3 3 3 2 Sugar (and other) transporter SPC25 PF06703.11 KND97023.1 - 6.7 6.5 6.3 2.8 7.7 0.0 2.8 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Sugar_tr PF00083.24 KND97026.1 - 1e-131 440.0 17.9 1.1e-131 439.8 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND97026.1 - 1.7e-26 93.0 16.2 1.7e-26 93.0 16.2 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.9 KND97026.1 - 0.06 13.6 5.3 0.039 14.2 1.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) Sugar_tr PF00083.24 KND97028.1 - 5.6e-94 315.5 15.9 7.1e-94 315.2 15.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND97028.1 - 2.5e-16 59.6 23.1 1.8e-15 56.7 11.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Fasciclin PF02469.22 KND97030.1 - 5.7e-11 42.7 3.7 0.0002 21.6 0.1 4.6 5 1 0 5 5 5 3 Fasciclin domain RRM_1 PF00076.22 KND97031.1 - 1.2e-18 66.6 0.0 2.2e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KND97031.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.6 1 1 0 1 1 1 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KND97031.1 - 0.17 11.9 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif FMN_bind_2 PF04299.12 KND97032.1 - 1.4e-58 197.3 0.2 1.7e-58 197.0 0.2 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Epimerase PF01370.21 KND97036.1 - 5e-20 72.0 0.0 7.2e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KND97036.1 - 4.2e-11 42.4 0.0 5.7e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KND97036.1 - 1.1e-09 38.1 0.0 2.4e-09 37.0 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KND97036.1 - 7.9e-07 28.5 0.0 4.5e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KND97036.1 - 1.5e-06 27.8 0.0 2.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND97036.1 - 0.00029 20.5 0.0 0.0005 19.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KND97036.1 - 0.00064 18.9 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KND97036.1 - 0.00081 19.3 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KND97036.1 - 0.00097 19.1 0.1 0.0034 17.3 0.1 2.0 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KND97036.1 - 0.0059 16.2 0.0 0.015 14.8 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family CTV_P33 PF07184.11 KND97036.1 - 0.18 10.8 0.0 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 Citrus tristeza virus P33 protein SP2 PF03014.14 KND97037.1 - 0.15 10.4 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 Structural protein 2 VIT1 PF01988.19 KND97039.1 - 2.2e-64 217.3 1.8 3.4e-64 216.6 1.8 1.3 1 0 0 1 1 1 1 VIT family Fun_ATP-synt_8 PF05933.13 KND97039.1 - 0.15 12.2 4.6 0.3 11.3 4.6 1.4 1 0 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) Sugar_tr PF00083.24 KND97043.1 - 1.1e-119 400.2 25.6 1.4e-119 400.0 25.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND97043.1 - 1.7e-16 60.1 27.1 1.6e-12 47.1 1.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.7 KND97046.1 - 1.1e-31 109.2 0.1 9.2e-10 39.0 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KND97046.1 - 2.2e-29 101.1 4.7 2.5e-10 40.4 0.0 4.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KND97046.1 - 1.2e-28 99.1 0.6 1.5e-09 38.2 0.1 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND97046.1 - 5.8e-26 87.7 0.2 0.0048 17.3 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 KND97046.1 - 1.9e-20 72.3 3.8 0.0012 19.2 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat MARVEL PF01284.23 KND97047.1 - 1.8e-27 96.1 22.3 2.1e-27 95.9 22.3 1.0 1 0 0 1 1 1 1 Membrane-associating domain zinc_ribbon_4 PF13717.6 KND97047.1 - 0.1 12.6 0.3 0.17 11.8 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbon domain DUF4956 PF16316.5 KND97047.1 - 0.35 10.5 5.9 3.2 7.4 0.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4956) CcmH PF03918.14 KND97047.1 - 4.8 6.5 4.8 1.5 8.1 0.2 2.3 2 1 1 3 3 3 0 Cytochrome C biogenesis protein SKN1 PF03935.15 KND97050.1 - 8.8e-243 806.2 4.6 1e-242 806.0 4.6 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.15 KND97052.1 - 8.9e-237 786.4 3.7 1e-236 786.2 3.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) ketoacyl-synt PF00109.26 KND97053.1 - 6.3e-57 193.0 0.2 2.8e-56 190.9 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KND97053.1 - 3.5e-35 120.6 0.7 3.5e-35 120.6 0.7 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KND97053.1 - 8.3e-08 31.9 0.4 7.1e-05 22.3 0.1 3.0 3 0 0 3 3 3 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 KND97053.1 - 0.026 14.2 1.0 0.4 10.3 0.2 2.8 3 0 0 3 3 3 0 Thiolase, C-terminal domain WW PF00397.26 KND97054.1 - 5.4e-05 23.2 0.5 0.0001 22.3 0.5 1.5 1 0 0 1 1 1 1 WW domain Pept_S41_N PF18294.1 KND97054.1 - 0.0086 16.0 0.3 0.026 14.5 0.3 1.8 1 0 0 1 1 1 1 Peptidase S41 N-terminal domain FF PF01846.19 KND97054.1 - 0.024 14.8 0.4 0.072 13.3 0.4 1.8 1 0 0 1 1 1 0 FF domain zf-C2H2 PF00096.26 KND97057.1 - 6.8e-11 42.0 9.3 4.5e-05 23.7 4.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND97057.1 - 4.2e-08 33.3 7.9 0.0017 19.0 0.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KND97057.1 - 0.00058 20.1 0.9 0.0057 16.9 0.9 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KND97057.1 - 0.00058 20.2 0.7 0.66 10.4 0.8 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type DUF2256 PF10013.9 KND97057.1 - 0.0037 17.4 1.1 1.5 9.0 0.1 2.4 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2256) zf-MYST PF17772.1 KND97057.1 - 0.0053 16.3 1.1 0.45 10.2 0.0 2.2 1 1 1 2 2 2 1 MYST family zinc finger domain zf-Di19 PF05605.12 KND97057.1 - 0.0097 16.2 3.8 0.023 15.0 3.8 1.7 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 KND97057.1 - 0.011 16.4 0.2 3.1 8.5 0.1 2.2 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats DUF2321 PF10083.9 KND97057.1 - 0.021 14.4 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-H2C2_2 PF13465.6 KND97057.1 - 0.023 15.1 8.5 0.78 10.3 1.0 3.1 3 0 0 3 3 3 0 Zinc-finger double domain TRAF6_Z2 PF18048.1 KND97057.1 - 0.032 14.3 1.9 0.073 13.2 0.4 2.1 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-met2 PF12907.7 KND97057.1 - 0.16 12.1 5.4 0.68 10.1 0.0 2.4 2 1 0 2 2 2 0 Zinc-binding zf_C2H2_ZHX PF18387.1 KND97057.1 - 0.63 9.7 3.8 4.4 7.0 0.0 2.2 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-BED PF02892.15 KND97057.1 - 0.96 9.5 5.6 3.2 7.9 2.3 2.3 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_11 PF16622.5 KND97057.1 - 4.7 7.1 10.1 0.1 12.4 2.3 2.1 2 1 0 2 2 2 0 zinc-finger C2H2-type NCA2 PF08637.10 KND97058.1 - 2.8e-77 259.7 4.9 4.2e-77 259.2 4.9 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Mannosyl_trans3 PF11051.8 KND97060.1 - 6.6e-53 179.8 0.1 1.5e-52 178.7 0.0 1.6 2 0 0 2 2 2 1 Mannosyltransferase putative YusW PF14039.6 KND97060.1 - 0.00034 21.1 1.5 0.0007 20.1 1.5 1.5 1 0 0 1 1 1 1 YusW-like protein Asp PF00026.23 KND97062.1 - 5.1e-64 216.7 4.3 6.1e-64 216.4 4.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KND97062.1 - 1.8e-12 47.8 0.1 5.4e-05 23.5 0.0 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KND97062.1 - 0.0013 19.4 0.1 0.64 10.7 0.1 3.3 2 1 0 2 2 2 2 Aspartyl protease MFS_1 PF07690.16 KND97063.1 - 3.8e-13 49.1 40.1 6e-07 28.7 22.7 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily ESSS PF10183.9 KND97063.1 - 7.9 6.8 6.5 46 4.3 0.1 3.5 3 1 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Utp14 PF04615.13 KND97065.1 - 0.0031 16.2 6.8 0.0043 15.7 6.8 1.1 1 0 0 1 1 1 1 Utp14 protein DUF1011 PF06237.12 KND97065.1 - 0.0062 16.8 5.6 1 9.7 0.1 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1011) Spt5_N PF11942.8 KND97065.1 - 0.075 14.0 6.9 2.7 9.0 0.3 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PBP1_TM PF14812.6 KND97065.1 - 0.17 12.3 12.8 0.68 10.3 2.8 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 KND97065.1 - 0.19 11.0 3.9 2 7.7 0.6 2.2 2 0 0 2 2 2 0 NOA36 protein Importin_rep_4 PF18808.1 KND97065.1 - 3 8.2 9.2 8.4 6.7 1.3 2.3 2 0 0 2 2 2 0 Importin repeat oligo_HPY PF08352.12 KND97065.1 - 3.1 8.4 5.3 15 6.2 1.0 2.7 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region MFS_1 PF07690.16 KND97066.1 - 1.4e-10 40.6 37.6 1.1e-05 24.5 21.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily SLC3A2_N PF16028.5 KND97066.1 - 0.14 11.7 1.4 0.28 10.7 0.0 2.2 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus DUF688 PF05097.12 KND97066.1 - 0.17 11.0 0.4 0.25 10.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) DUF1935 PF09149.10 KND97069.1 - 0.018 15.4 0.1 0.035 14.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) MFS_1 PF07690.16 KND97071.1 - 2.5e-10 39.8 26.4 4.1e-09 35.8 10.0 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily Herpes_US9 PF06072.11 KND97071.1 - 0.0049 16.7 0.0 0.033 14.1 0.0 2.4 1 0 0 1 1 1 1 Alphaherpesvirus tegument protein US9 DUF2721 PF11026.8 KND97071.1 - 0.022 14.7 0.0 0.022 14.7 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2721) dCMP_cyt_deam_1 PF00383.23 KND97071.1 - 0.1 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region UPF0242 PF06785.11 KND97071.1 - 0.11 12.6 0.4 0.16 12.0 0.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2583 PF10762.9 KND97071.1 - 3.8 8.0 5.6 7.2 7.1 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2583) Zn_clus PF00172.18 KND97072.1 - 3.3e-08 33.5 13.9 6.9e-08 32.5 13.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND97072.1 - 0.00024 20.2 0.8 0.00038 19.6 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KND97073.1 - 6e-49 167.0 0.0 9e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FleQ PF06490.11 KND97074.1 - 0.073 13.4 0.1 0.078 13.3 0.1 1.1 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ Sugar_tr PF00083.24 KND97075.1 - 8.7e-87 291.8 28.2 1e-86 291.6 28.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND97075.1 - 1.8e-25 89.6 38.5 6.6e-20 71.3 30.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND97076.1 - 1.9e-88 297.3 24.5 2.3e-88 297.1 24.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND97076.1 - 2.4e-26 92.5 40.3 6.7e-21 74.6 30.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PTR2 PF00854.21 KND97076.1 - 6.8 5.4 17.2 0.27 10.0 2.1 3.7 3 1 1 4 4 4 0 POT family DUF4579 PF15158.6 KND97076.1 - 8.8 6.0 6.7 1.6 8.5 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) Sugar_tr PF00083.24 KND97078.1 - 9.7e-87 291.7 25.7 1.1e-86 291.5 25.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND97078.1 - 4.8e-24 84.9 57.8 4.8e-19 68.5 28.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_5_C PF18564.1 KND97079.1 - 1.4e-11 44.7 0.0 2.8e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KND97079.1 - 8.1e-10 38.6 1.1 1.1e-05 25.1 0.4 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) RVT_1 PF00078.27 KND97084.1 - 2.2e-07 30.6 0.1 4e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Reticulon PF02453.17 KND97086.1 - 0.0079 16.2 0.2 0.0086 16.1 0.2 1.1 1 0 0 1 1 1 1 Reticulon Sugar_tr PF00083.24 KND97087.1 - 1e-91 308.1 27.2 1.1e-91 308.0 27.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND97087.1 - 4.1e-30 104.9 18.8 4.1e-30 104.9 18.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily CCDC24 PF15669.5 KND97087.1 - 0.042 13.7 0.0 0.063 13.1 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family MFS_3 PF05977.13 KND97087.1 - 0.1 11.0 5.6 0.17 10.3 5.6 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector Mer2 PF09074.10 KND97087.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Mer2 Sugar_tr PF00083.24 KND97089.1 - 3.6e-90 303.0 25.6 4.1e-90 302.8 25.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND97089.1 - 1.1e-31 110.1 20.9 1.1e-31 110.1 20.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KND97089.1 - 1.9e-06 26.6 6.1 2.9e-06 26.0 6.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_3_C PF01915.22 KND97090.1 - 1.5e-52 178.5 0.0 2.2e-52 178.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KND97090.1 - 1.5e-35 123.1 0.0 2.6e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KND97090.1 - 6e-16 58.3 0.1 1.2e-15 57.4 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KND97090.1 - 1e-07 31.9 0.0 1.9e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Pex24p PF06398.11 KND97091.1 - 0.017 14.1 3.8 0.032 13.2 3.8 1.5 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin MFS_1 PF07690.16 KND97092.1 - 8.2e-10 38.1 43.6 2.4e-05 23.4 28.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KND97092.1 - 0.00037 19.1 22.7 0.00076 18.0 5.6 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Peptidase_A24 PF01478.18 KND97092.1 - 0.048 14.1 0.7 0.048 14.1 0.7 3.2 2 2 1 3 3 3 0 Type IV leader peptidase family Glyco_hydro_72 PF03198.14 KND97093.1 - 2.3e-63 214.4 0.4 2.9e-63 214.0 0.4 1.1 1 0 0 1 1 1 1 Glucanosyltransferase F-box-like PF12937.7 KND97094.1 - 6.9e-10 38.7 1.1 1.1e-09 38.0 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KND97094.1 - 1.1e-05 25.2 0.6 4.3e-05 23.3 0.1 2.3 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KND97094.1 - 0.001 18.9 0.0 0.0038 17.1 0.0 1.9 2 0 0 2 2 2 1 F-box LUC7 PF03194.15 KND97095.1 - 1.1e-57 195.6 0.2 1.2e-57 195.4 0.2 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DpnI PF06044.12 KND97095.1 - 0.035 13.8 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Dam-replacing family MCR_D PF02505.14 KND97095.1 - 0.061 13.2 0.4 0.1 12.5 0.4 1.4 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein D V-SNARE PF05008.15 KND97095.1 - 0.096 13.1 1.8 0.11 12.9 0.5 1.8 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Peptidase_M48 PF01435.18 KND97096.1 - 3.3e-39 134.7 0.0 5.6e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M48_N PF16491.5 KND97096.1 - 5.8e-32 111.1 9.2 5.8e-32 111.1 9.2 2.1 2 1 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices PH_12 PF16457.5 KND97099.1 - 7.8e-29 100.9 0.2 1.8e-28 99.8 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DEAD PF00270.29 KND97100.1 - 6.6e-46 156.3 0.1 1.4e-45 155.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND97100.1 - 5.7e-27 94.3 0.0 2.7e-26 92.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SYS1 PF09801.9 KND97101.1 - 9.1e-52 175.1 17.1 1.1e-51 174.8 17.1 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network SCP2 PF02036.17 KND97103.1 - 1.9e-17 63.6 0.4 2.3e-17 63.3 0.4 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KND97103.1 - 0.0019 18.5 0.0 0.0024 18.1 0.0 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal p450 PF00067.22 KND97104.1 - 1.1e-63 215.6 0.1 1.5e-63 215.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KND97105.1 - 3.6e-45 154.6 0.0 1.7e-44 152.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Vac7 PF12751.7 KND97106.1 - 7.9e-24 84.8 38.1 3e-19 69.7 0.1 3.9 1 1 3 4 4 4 2 Vacuolar segregation subunit 7 6PF2K PF01591.18 KND97107.1 - 2.8e-75 252.4 0.0 7.6e-75 251.0 0.0 1.7 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KND97107.1 - 1.6e-29 103.0 0.0 1.3e-22 80.4 0.0 2.7 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KND97107.1 - 0.039 14.1 0.2 0.36 11.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain KTI12 PF08433.10 KND97107.1 - 0.054 12.9 0.1 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 eIF_4EBP PF05456.11 KND97107.1 - 5.8 6.9 6.3 20 5.1 1.7 2.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Lysyl_oxidase PF01186.17 KND97108.1 - 0.13 11.9 0.3 0.29 10.8 0.2 1.5 1 1 1 2 2 2 0 Lysyl oxidase Methyltransf_16 PF10294.9 KND97112.1 - 6.1e-06 26.1 0.1 0.00073 19.3 0.0 2.2 1 1 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 KND97112.1 - 0.036 13.9 0.0 0.15 11.9 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Xpo1 PF08389.12 KND97113.1 - 2e-05 24.7 9.9 9.4e-05 22.5 0.5 5.1 6 0 0 6 6 6 1 Exportin 1-like protein IBN_N PF03810.19 KND97113.1 - 0.0016 18.3 0.9 0.21 11.5 0.0 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Brix PF04427.18 KND97115.1 - 4.1e-27 95.5 0.5 6.2e-27 94.9 0.5 1.2 1 0 0 1 1 1 1 Brix domain ATF7IP_BD PF16788.5 KND97115.1 - 5.5 7.0 9.8 2.8 8.0 7.4 1.6 2 0 0 2 2 2 0 ATF-interacting protein binding domain BSD PF03909.17 KND97116.1 - 3e-22 78.4 0.2 2.3e-14 53.1 0.1 2.9 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 KND97116.1 - 1.3e-12 47.9 0.2 2.7e-12 46.9 0.2 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DUF3316 PF11777.8 KND97116.1 - 0.09 12.8 0.1 9.4 6.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3316) MaoC_dehydrat_N PF13452.6 KND97117.1 - 3.2e-05 24.1 0.0 0.054 13.6 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.19 KND97117.1 - 8e-05 22.2 0.0 0.00043 19.8 0.0 1.9 2 0 0 2 2 2 1 MaoC like domain DNA_pack_N PF02500.15 KND97117.1 - 0.031 14.1 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus Ribonuclease_T2 PF00445.18 KND97118.1 - 1.7e-39 135.9 1.3 2e-39 135.7 1.3 1.0 1 0 0 1 1 1 1 Ribonuclease T2 family Sod_Cu PF00080.20 KND97119.1 - 4.9e-38 130.5 2.0 5.4e-38 130.3 2.0 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF1772 PF08592.11 KND97120.1 - 0.004 17.5 0.0 0.0041 17.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) PhoR PF11808.8 KND97120.1 - 0.013 15.9 0.0 0.016 15.6 0.0 1.2 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR Inhibitor_I9 PF05922.16 KND97121.1 - 3.6e-09 37.2 0.0 1.3e-08 35.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase inhibitor I9 Glyco_hydro_38N PF01074.22 KND97122.1 - 1.1e-79 267.8 0.8 1.6e-79 267.3 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KND97122.1 - 4.6e-49 167.4 0.2 8.8e-49 166.5 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KND97122.1 - 1e-26 92.9 0.0 2.6e-26 91.6 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KND97122.1 - 2.2e-08 34.1 0.2 4e-07 30.0 0.2 2.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain SBDS PF01172.18 KND97123.1 - 1.3e-34 118.1 0.4 2.8e-34 117.0 0.4 1.6 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 KND97123.1 - 1.3e-30 105.8 1.6 1.4e-30 105.7 0.6 1.6 2 0 0 2 2 2 1 SBDS protein C-terminal domain RAC_head PF16717.5 KND97124.1 - 1.5e-21 77.2 3.4 1.5e-21 77.2 3.4 3.3 2 1 0 2 2 2 1 Ribosome-associated complex head domain DnaJ PF00226.31 KND97124.1 - 2.9e-16 59.4 0.1 2.9e-16 59.4 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain IPP-2 PF04979.14 KND97125.1 - 6.3e-22 78.7 15.2 6.3e-22 78.7 15.2 1.7 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Arf PF00025.21 KND97126.1 - 2.4e-75 251.8 0.2 2.7e-75 251.6 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KND97126.1 - 2.8e-16 59.8 0.0 3.8e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KND97126.1 - 5.6e-11 42.2 0.0 7.5e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KND97126.1 - 2e-10 40.4 0.6 2.8e-06 26.7 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KND97126.1 - 2.3e-10 40.3 0.0 2.6e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KND97126.1 - 6.3e-10 38.8 0.0 7.9e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KND97126.1 - 0.00013 22.0 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 KND97126.1 - 0.00015 20.8 0.4 0.0051 15.8 0.1 2.4 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 KND97126.1 - 0.0027 17.3 0.1 0.03 13.9 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KND97126.1 - 0.0033 17.9 0.1 0.0085 16.6 0.1 1.7 1 1 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 KND97126.1 - 0.049 14.2 0.1 0.074 13.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain PDH PF02153.17 KND97127.1 - 4.5e-15 55.4 0.0 7e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 KND97127.1 - 2.2e-08 34.4 0.0 4.2e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KND97127.1 - 1.5e-06 28.7 0.1 3.8e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KND97127.1 - 2.6e-05 23.7 0.1 5e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KND97127.1 - 0.00015 21.7 0.1 0.00027 20.9 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KND97127.1 - 0.0022 17.7 0.0 0.0047 16.6 0.0 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 KND97127.1 - 0.0034 17.0 0.2 0.0061 16.1 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KND97127.1 - 0.0088 16.3 0.0 0.027 14.7 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain Rossmann-like PF10727.9 KND97127.1 - 0.0093 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Rossmann-like domain Shikimate_DH PF01488.20 KND97127.1 - 0.035 14.2 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 KND97127.1 - 0.049 13.2 0.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GHMP_kinases_N PF00288.26 KND97129.1 - 3.8e-14 52.7 0.1 9.6e-14 51.4 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KND97129.1 - 1.4e-06 28.5 0.0 8.4e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 GHMP kinases C terminal MitoNEET_N PF10660.9 KND97130.1 - 0.46 10.6 3.5 1.7 8.8 0.3 2.8 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus DUF3681 PF12442.8 KND97130.1 - 0.56 10.7 0.0 0.56 10.7 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3681) Kelch_4 PF13418.6 KND97131.1 - 0.0019 18.1 0.2 0.072 13.1 0.0 3.4 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.6 KND97131.1 - 0.0033 17.4 3.8 6.8 6.8 0.1 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 KND97131.1 - 0.013 15.1 1.5 0.042 13.4 0.1 2.6 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.15 KND97131.1 - 0.057 13.4 4.0 0.31 11.1 0.0 3.8 4 0 0 4 4 4 0 Kelch motif zf-Tim10_DDP PF02953.15 KND97132.1 - 1.6e-20 72.5 1.8 2e-20 72.2 1.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF825 PF05695.12 KND97132.1 - 0.074 10.2 0.1 0.077 10.2 0.1 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) Tom5 PF10642.9 KND97132.1 - 0.21 11.7 1.3 0.23 11.5 0.3 1.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Cyto_heme_lyase PF01265.17 KND97133.1 - 9.8e-44 150.1 4.0 2.5e-43 148.8 4.0 1.5 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase SURF4 PF02077.15 KND97135.1 - 1.1e-90 303.9 12.9 1.2e-90 303.7 12.9 1.0 1 0 0 1 1 1 1 SURF4 family RNase_PH PF01138.21 KND97136.1 - 3.9e-33 114.8 0.1 5.6e-33 114.2 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KND97136.1 - 1.9e-07 31.0 0.3 3.6e-07 30.1 0.3 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Mannosyl_trans PF05007.13 KND97137.1 - 4.8e-73 246.2 21.5 6.8e-73 245.7 21.5 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KND97137.1 - 8.8e-14 51.3 9.4 8.8e-14 51.3 9.4 2.1 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 KND97137.1 - 0.004 16.9 10.8 0.0056 16.4 7.0 2.1 1 1 1 2 2 2 1 Glycosyltransferase family 87 DUF5572 PF17733.1 KND97138.1 - 2.8e-22 78.3 1.5 3.2e-22 78.1 0.3 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5572) Mito_carr PF00153.27 KND97139.1 - 1.1e-48 163.1 1.3 2.8e-19 68.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein LapA_dom PF06305.11 KND97139.1 - 0.24 11.2 0.9 4.2 7.3 0.0 3.1 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain DUF383 PF04063.14 KND97140.1 - 5e-67 225.3 2.0 3.8e-66 222.4 0.2 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KND97140.1 - 1.3e-22 79.4 1.0 7e-22 77.0 1.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF384) Peptidase_C50 PF03568.17 KND97140.1 - 0.0023 17.1 0.0 0.0055 15.9 0.0 1.5 1 1 0 1 1 1 1 Peptidase family C50 Type_III_YscX PF09474.10 KND97140.1 - 0.15 12.4 1.5 4.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) Peptidase_M20 PF01546.28 KND97141.1 - 9.5e-29 100.6 0.0 1.4e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KND97141.1 - 4.3e-13 49.1 0.1 1.4e-12 47.5 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KND97141.1 - 1.4e-06 28.2 0.0 2.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 YwhD PF08741.10 KND97141.1 - 0.16 11.6 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 YwhD family DLH PF01738.18 KND97142.1 - 2.8e-32 112.0 0.0 3.1e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KND97142.1 - 0.038 13.6 0.0 4.1 7.0 0.0 2.4 1 1 1 2 2 2 0 alpha/beta hydrolase fold ABC1 PF03109.16 KND97143.1 - 3.3e-23 82.1 0.2 4.6e-14 52.6 0.1 2.6 2 0 0 2 2 2 2 ABC1 family RIO1 PF01163.22 KND97143.1 - 0.00083 19.0 0.2 0.0035 17.0 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 KND97143.1 - 0.034 13.5 1.6 0.66 9.3 0.5 2.6 2 0 0 2 2 2 0 Protein kinase domain HEPN_DZIP3 PF18738.1 KND97143.1 - 0.095 12.4 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 DZIP3/ hRUL138-like HEPN DUF676 PF05057.14 KND97144.1 - 5.5e-42 143.7 0.0 8.4e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KND97144.1 - 0.00023 21.1 0.0 0.00035 20.5 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 KND97144.1 - 0.0044 16.9 0.0 0.0078 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 KND97144.1 - 0.015 15.1 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein DLH PF01738.18 KND97144.1 - 0.1 12.1 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KND97144.1 - 0.12 13.0 0.0 0.18 12.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Proteasome PF00227.26 KND97145.1 - 1e-37 129.5 0.1 6.1e-37 127.0 0.1 1.8 1 1 0 1 1 1 1 Proteasome subunit ER_lumen_recept PF00810.18 KND97146.1 - 4.6e-52 176.7 11.7 4.6e-52 176.7 11.7 1.7 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KND97146.1 - 0.00082 19.1 13.0 0.31 10.8 0.4 4.4 2 1 2 4 4 4 3 PQ loop repeat DUF1516 PF07457.11 KND97146.1 - 0.0011 19.1 5.5 0.0029 17.8 5.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1516) Thioredoxin PF00085.20 KND97147.1 - 3.2e-15 56.0 0.1 3.8e-13 49.3 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 KND97147.1 - 2.3e-08 34.4 0.5 9.4e-05 22.8 0.3 3.1 2 2 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KND97147.1 - 4.9e-07 29.4 1.7 2.2e-05 24.0 0.1 2.1 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family TraF PF13728.6 KND97147.1 - 1.5e-06 28.2 0.0 3.4e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 KND97147.1 - 4.7e-06 26.8 4.7 0.046 14.1 0.2 4.4 2 2 1 3 3 3 2 Thioredoxin-like Thioredoxin_6 PF13848.6 KND97147.1 - 1.7e-05 24.8 6.5 0.0066 16.4 1.2 2.7 2 1 0 2 2 2 2 Thioredoxin-like domain HyaE PF07449.11 KND97147.1 - 0.00056 19.9 0.0 0.9 9.5 0.0 2.5 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 KND97147.1 - 0.059 13.3 0.2 0.2 11.6 0.1 2.0 1 1 1 2 2 2 0 AhpC/TSA family Flocculin_t3 PF13928.6 KND97148.1 - 5.5e-24 84.4 97.2 8.5e-13 48.6 18.4 5.7 6 0 0 6 6 6 4 Flocculin type 3 repeat DUF5563 PF17718.1 KND97148.1 - 0.24 11.0 1.3 0.4 10.2 1.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5563) CPSF_A PF03178.15 KND97149.1 - 1.8e-91 306.8 0.0 9.7e-90 301.1 0.0 2.4 2 0 0 2 2 2 2 CPSF A subunit region MMS1_N PF10433.9 KND97149.1 - 3.2e-22 78.8 2.1 6.9e-22 77.7 2.1 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PIG-F PF06699.11 KND97151.1 - 1.3e-46 159.1 11.9 1.6e-46 158.7 11.9 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F 7TM_GPCR_Srz PF10325.9 KND97151.1 - 0.02 14.2 4.1 0.026 13.9 4.1 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz GNVR PF13807.6 KND97151.1 - 0.037 13.9 1.1 3.4 7.6 0.3 3.1 3 0 0 3 3 3 0 G-rich domain on putative tyrosine kinase PRA1 PF03208.19 KND97151.1 - 0.053 13.1 15.3 0.027 14.1 10.1 2.2 1 1 2 3 3 3 0 PRA1 family protein tRNA-synt_1b PF00579.25 KND97153.1 - 9.6e-71 238.5 0.0 1.2e-70 238.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) zf-UBR PF02207.20 KND97154.1 - 2.3e-16 59.7 12.6 1.1e-15 57.5 12.6 2.2 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KND97154.1 - 2.4e-06 27.2 0.0 7e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-UBR PF02207.20 KND97155.1 - 1.9e-18 66.4 9.4 7.3e-18 64.5 9.4 2.1 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KND97155.1 - 0.01 15.6 0.0 0.036 13.8 0.0 1.9 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.6 KND97155.1 - 0.025 14.9 0.7 0.025 14.9 0.7 4.1 3 0 0 3 3 3 0 Ring finger domain zf-CXXC PF02008.20 KND97155.1 - 0.17 11.9 2.7 0.66 10.0 2.7 2.0 1 0 0 1 1 1 0 CXXC zinc finger domain UCH PF00443.29 KND97155.1 - 3.7 6.9 4.8 6 6.3 0.0 3.0 3 0 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase SH3_9 PF14604.6 KND97156.1 - 4.5e-24 84.0 4.0 8.7e-12 44.7 0.2 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KND97156.1 - 1.3e-23 82.4 7.2 2.4e-11 43.0 1.2 2.5 2 0 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.20 KND97156.1 - 7.9e-21 74.1 0.0 2.5e-20 72.5 0.0 1.9 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 KND97156.1 - 7.8e-14 51.1 0.2 4.3e-06 26.3 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SPRY PF00622.28 KND97159.1 - 3.7e-14 52.9 0.0 6.8e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 SPRY domain COX4 PF02936.14 KND97159.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Glyco_hydro_17 PF00332.18 KND97160.1 - 4.3e-61 207.2 2.0 4.8e-61 207.1 2.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 VWA_2 PF13519.6 KND97160.1 - 0.029 15.0 0.1 1.2 9.9 0.0 2.2 2 0 0 2 2 2 0 von Willebrand factor type A domain Methyltrn_RNA_3 PF02598.17 KND97162.1 - 1.9e-60 204.8 0.5 2.3e-60 204.6 0.5 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase Dynamitin PF04912.14 KND97163.1 - 0.0024 17.3 12.7 0.0024 17.3 12.7 3.9 1 1 3 4 4 4 1 Dynamitin Baculo_PEP_C PF04513.12 KND97163.1 - 0.057 13.5 19.1 4.4 7.3 0.2 4.9 3 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus V-SNARE PF05008.15 KND97163.1 - 0.17 12.2 0.2 0.17 12.2 0.2 6.3 3 2 2 5 5 5 0 Vesicle transport v-SNARE protein N-terminus DUF3584 PF12128.8 KND97163.1 - 0.18 9.3 46.8 0.073 10.6 38.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 KND97163.1 - 0.64 8.8 55.4 0.22 10.4 12.0 3.8 2 1 2 4 4 4 0 Spc7 kinetochore protein DUF4510 PF14971.6 KND97163.1 - 6.6 7.1 10.4 0.71 10.2 0.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4510) NUDIX PF00293.28 KND97164.1 - 3.7e-19 69.1 0.0 8.1e-19 68.0 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain LIAS_N PF16881.5 KND97165.1 - 2.2e-19 69.9 0.1 4.1e-19 69.0 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KND97165.1 - 5.9e-10 39.8 0.0 9.6e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Hist_deacetyl PF00850.19 KND97167.1 - 4.4e-50 170.9 0.0 1.8e-48 165.6 0.0 2.2 1 1 0 1 1 1 1 Histone deacetylase domain RhoGAP PF00620.27 KND97168.1 - 1.5e-28 99.5 1.2 4.7e-28 97.9 0.0 2.4 3 0 0 3 3 3 1 RhoGAP domain PH PF00169.29 KND97168.1 - 9.9e-12 45.3 0.0 2.9e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 PH domain PX PF00787.24 KND97168.1 - 0.00045 20.2 0.2 0.0039 17.2 0.0 2.5 3 0 0 3 3 3 1 PX domain PH_11 PF15413.6 KND97168.1 - 0.04 14.4 0.8 0.14 12.6 0.0 2.4 2 1 0 2 2 2 0 Pleckstrin homology domain PH_6 PF15406.6 KND97168.1 - 0.051 13.9 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain DUF5433 PF17498.2 KND97168.1 - 0.13 12.4 0.1 0.31 11.3 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5433) TFIIA PF03153.13 KND97169.1 - 2.8e-52 179.1 21.0 2.3e-29 103.7 14.1 2.1 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Rer1 PF03248.13 KND97171.1 - 1.6e-76 255.8 2.4 1.8e-76 255.6 2.4 1.0 1 0 0 1 1 1 1 Rer1 family ANTH PF07651.16 KND97172.1 - 1.4e-77 260.5 0.7 1.4e-77 260.5 0.7 3.3 4 1 1 5 5 5 1 ANTH domain I_LWEQ PF01608.17 KND97172.1 - 1.8e-54 184.1 9.6 1.8e-54 184.1 9.6 5.5 3 1 2 5 5 5 1 I/LWEQ domain Spc7 PF08317.11 KND97172.1 - 3e-05 23.0 19.5 3e-05 23.0 19.5 5.5 2 2 3 5 5 5 1 Spc7 kinetochore protein DDE_Tnp_1_2 PF13586.6 KND97172.1 - 0.14 12.6 0.2 0.14 12.6 0.2 2.5 3 0 0 3 3 3 0 Transposase DDE domain SapB_1 PF05184.15 KND97172.1 - 0.94 9.6 2.8 1.4 9.0 0.0 2.8 2 0 0 2 2 2 0 Saposin-like type B, region 1 Mito_carr PF00153.27 KND97173.1 - 1.3e-55 185.3 1.7 2.7e-17 62.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein UCR_14kD PF02271.16 KND97175.1 - 1.1e-27 95.9 0.3 1.3e-27 95.7 0.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit ATP_transf PF09830.9 KND97176.1 - 1.6e-17 63.4 0.0 2.8e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.23 KND97176.1 - 0.0013 19.4 0.0 0.0034 18.1 0.0 1.6 2 0 0 2 2 2 1 HIT domain DUF4922 PF16269.5 KND97176.1 - 0.0024 17.7 0.2 0.0038 17.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4922) DUF4931 PF16285.5 KND97176.1 - 0.067 12.5 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) Spb1_C PF07780.12 KND97178.1 - 2.3e-81 272.5 16.1 2.3e-81 272.5 16.1 3.2 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 KND97178.1 - 2.4e-54 184.1 0.4 8.2e-54 182.4 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KND97178.1 - 1.6e-39 135.3 16.9 1.6e-39 135.3 16.9 4.1 3 2 1 4 4 4 1 Domain of unknown function (DUF3381) GP24_25 PF17388.2 KND97178.1 - 2.3 8.2 10.4 0.049 13.6 0.7 3.1 3 0 0 3 3 3 0 Tail assembly gene products 24 & 25 Pep3_Vps18 PF05131.14 KND97179.1 - 2.7e-16 59.7 0.1 1.3e-14 54.2 0.0 2.6 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Vps39_2 PF10367.9 KND97179.1 - 2.8e-08 34.2 2.1 2.8e-08 34.2 2.1 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Prok-RING_1 PF14446.6 KND97179.1 - 0.00045 20.1 0.6 0.001 18.9 0.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.6 KND97179.1 - 0.0015 18.3 1.5 0.0044 16.8 1.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KND97179.1 - 0.0016 18.7 1.7 0.0016 18.7 1.7 2.3 3 0 0 3 3 2 1 Ring finger domain Zn_ribbon_17 PF17120.5 KND97179.1 - 0.0017 17.9 1.5 0.0051 16.4 1.5 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KND97179.1 - 0.007 16.6 0.7 0.007 16.6 0.7 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KND97179.1 - 0.011 15.8 1.4 0.024 14.7 1.4 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 KND97179.1 - 0.02 14.6 4.9 0.06 13.1 4.9 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 KND97179.1 - 0.058 13.4 2.0 0.16 12.0 2.0 1.7 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.29 KND97179.1 - 0.22 11.4 1.2 0.52 10.2 1.2 1.6 1 0 0 1 1 1 0 PHD-finger zf-C3H2C3 PF17122.5 KND97179.1 - 0.26 11.3 3.0 0.61 10.2 3.0 1.6 1 0 0 1 1 1 0 Zinc-finger zf-C3HC4 PF00097.25 KND97179.1 - 0.32 10.9 1.2 0.86 9.5 1.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KND97179.1 - 1.1 9.4 3.8 1.1 9.5 1.8 2.0 2 0 0 2 2 2 0 zinc RING finger of MSL2 CH PF00307.31 KND97180.1 - 1.9e-79 262.9 0.0 2.5e-19 69.4 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KND97180.1 - 1.5e-08 34.4 0.0 0.2 11.5 0.0 4.4 4 0 0 4 4 4 3 CAMSAP CH domain CH_2 PF06294.11 KND97180.1 - 8.9e-07 28.9 0.2 0.38 10.9 0.0 4.5 5 0 0 5 5 5 2 CH-like domain in sperm protein EF-hand_1 PF00036.32 KND97180.1 - 0.00058 19.2 0.0 0.057 13.0 0.0 3.1 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KND97180.1 - 0.001 19.5 2.6 0.0014 19.1 0.6 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KND97180.1 - 0.1 12.6 2.0 6 7.1 0.0 3.8 4 0 0 4 4 4 0 EF-hand domain CBF PF03914.17 KND97180.1 - 0.15 12.1 0.1 0.61 10.1 0.0 2.0 2 0 0 2 2 2 0 CBF/Mak21 family Complex1_LYR PF05347.15 KND97181.1 - 3.7e-08 33.3 3.4 5.9e-08 32.6 3.4 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) RL10P_insert PF17777.1 KND97182.1 - 5.5e-20 71.1 0.0 9e-20 70.5 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KND97182.1 - 1.9e-12 47.2 0.1 2.8e-12 46.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 Sipho_tail PF05709.11 KND97182.1 - 0.0066 15.9 0.1 0.017 14.5 0.0 1.6 1 1 1 2 2 2 1 Phage tail protein CENP-C_C PF11699.8 KND97183.1 - 7.8e-15 54.9 0.0 1.9e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 KND97183.1 - 7e-05 23.5 9.0 7e-05 23.5 9.0 2.5 2 2 0 2 2 2 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 KND97183.1 - 0.00021 21.0 0.0 0.00046 19.8 0.0 1.6 1 0 0 1 1 1 1 Cupin domain CRT10 PF08728.10 KND97184.1 - 7.4e-79 265.7 1.1 5.6e-50 170.3 0.3 2.3 1 1 1 2 2 2 2 CRT10 Mycoplasma_p37 PF06646.11 KND97185.1 - 0.11 11.7 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 High affinity transport system protein p37 GAF_2 PF13185.6 KND97186.1 - 6.6e-13 49.1 0.0 8.4e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KND97186.1 - 8.8e-09 36.1 0.0 1e-08 35.9 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KND97186.1 - 9.3e-05 22.8 0.0 0.0002 21.7 0.0 1.5 1 1 0 1 1 1 1 GAF domain SpoVT_C PF15714.5 KND97186.1 - 0.019 15.0 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor KH_1 PF00013.29 KND97187.1 - 1e-39 134.2 0.8 5.4e-16 58.2 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KND97187.1 - 1.1e-08 34.8 5.5 0.012 15.5 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KND97187.1 - 3.3e-08 33.3 5.3 0.039 13.8 0.0 3.7 4 0 0 4 4 4 3 KH domain KH_5 PF13184.6 KND97187.1 - 1.3e-07 31.5 1.0 0.3 11.2 0.0 3.3 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 KND97187.1 - 0.13 12.3 0.0 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 KH-like RNA-binding domain Hemolysin_N PF12563.8 KND97188.1 - 0.051 13.2 0.0 9.2 5.8 0.0 2.2 2 0 0 2 2 2 0 Hemolytic toxin N terminal SRP54 PF00448.22 KND97194.1 - 3.9e-77 258.3 2.2 4.7e-77 258.1 1.0 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KND97194.1 - 5.7e-28 97.5 6.0 5.7e-28 97.5 6.0 3.7 2 1 0 2 2 1 1 Signal peptide binding domain SRP54_N PF02881.19 KND97194.1 - 7.9e-17 61.3 3.5 1.8e-16 60.1 3.5 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KND97194.1 - 2.1e-06 27.4 2.4 0.001 18.7 0.8 3.3 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 KND97194.1 - 0.00024 21.2 0.0 0.0009 19.3 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 KND97194.1 - 0.00075 19.7 0.0 0.0019 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KND97194.1 - 0.0056 15.7 1.6 0.015 14.3 0.1 2.4 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 KND97194.1 - 0.0077 16.1 0.0 0.0077 16.1 0.0 2.0 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.20 KND97194.1 - 0.02 14.8 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_31 PF13614.6 KND97194.1 - 0.021 14.7 1.3 0.13 12.1 0.1 2.5 1 1 0 2 2 2 0 AAA domain MipZ PF09140.11 KND97194.1 - 0.034 13.4 0.2 6.1 6.0 0.0 2.5 2 0 0 2 2 2 0 ATPase MipZ SRPRB PF09439.10 KND97194.1 - 0.039 13.4 4.7 4.5 6.7 0.0 3.8 4 0 0 4 4 4 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 KND97194.1 - 0.06 13.9 0.5 0.42 11.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain 6PF2K PF01591.18 KND97194.1 - 0.088 12.1 1.1 0.24 10.7 0.0 2.1 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Zeta_toxin PF06414.12 KND97194.1 - 0.1 11.8 1.4 0.65 9.2 0.0 2.5 3 0 0 3 3 3 0 Zeta toxin AAA_24 PF13479.6 KND97194.1 - 0.11 12.2 1.5 0.55 9.9 0.1 2.6 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KND97194.1 - 0.16 12.4 0.0 0.46 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 KND97194.1 - 0.21 11.3 0.1 0.21 11.3 0.1 3.1 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 KND97194.1 - 0.64 9.9 3.3 0.45 10.4 0.1 2.3 3 0 0 3 3 3 0 NTPase DUF3145 PF11343.8 KND97195.1 - 0.034 13.7 0.1 0.082 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) LRR_1 PF00560.33 KND97195.1 - 1.2 9.9 8.7 35 5.5 0.0 6.1 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.7 KND97195.1 - 1.3 9.6 13.7 12 6.5 0.2 5.5 5 2 1 6 6 6 0 Leucine Rich repeats (2 copies) Elf1 PF05129.13 KND97196.1 - 1.1e-30 105.4 3.1 1.4e-30 105.1 3.1 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 KND97196.1 - 0.026 14.6 1.5 0.066 13.3 1.5 1.7 1 1 0 1 1 1 0 Zinc ribbon domain EST1_DNA_bind PF10373.9 KND97196.1 - 0.056 12.9 0.0 0.059 12.8 0.0 1.1 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain zf-FCS PF06467.14 KND97196.1 - 0.37 10.8 5.1 5.5 7.0 5.6 2.1 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-Sec23_Sec24 PF04810.15 KND97196.1 - 2 8.5 5.1 7.9 6.6 1.2 2.4 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger RabGAP-TBC PF00566.18 KND97197.1 - 2.2e-13 50.4 10.1 5.5e-13 49.1 10.1 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Bac_surface_Ag PF01103.23 KND97198.1 - 3.2e-12 46.6 9.1 5.5e-12 45.8 9.1 1.4 1 0 0 1 1 1 1 Surface antigen GHMP_kinases_N PF00288.26 KND97199.1 - 3.1e-10 40.1 0.0 6.2e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KND97199.1 - 1.7e-05 25.1 0.0 4.2e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal p450 PF00067.22 KND97200.1 - 1.1e-98 331.0 0.0 1.2e-98 330.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 7tm_3 PF00003.22 KND97200.1 - 0.12 12.0 0.2 0.19 11.4 0.2 1.2 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR HLH PF00010.26 KND97201.1 - 7.7e-16 57.8 0.1 7.7e-16 57.8 0.1 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF3752 PF12572.8 KND97201.1 - 0.025 15.1 2.1 0.062 13.8 2.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3752) NAD_binding_6 PF08030.12 KND97202.1 - 4.3e-24 85.4 0.0 6.3e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KND97202.1 - 2.1e-23 82.8 16.3 2.1e-23 82.8 13.0 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KND97202.1 - 2.1e-20 72.8 0.0 4.3e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain CFEM PF05730.11 KND97202.1 - 0.064 13.4 2.3 0.12 12.5 2.3 1.3 1 0 0 1 1 1 0 CFEM domain NAD_binding_1 PF00175.21 KND97202.1 - 0.13 13.0 0.1 24 5.6 0.0 2.4 1 1 1 2 2 2 0 Oxidoreductase NAD-binding domain Methyltransf_11 PF08241.12 KND97205.1 - 0.035 14.7 0.0 0.13 12.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 KND97205.1 - 0.085 13.6 0.0 0.27 12.0 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KND97205.1 - 0.15 12.8 0.1 0.47 11.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Peptidase_M16_C PF05193.21 KND97206.1 - 2.2e-34 119.0 0.0 2.5e-33 115.7 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KND97206.1 - 7.3e-32 110.4 0.0 1.3e-31 109.6 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) zf-UBP_var PF17807.1 KND97206.1 - 0.16 11.8 0.4 0.33 10.7 0.4 1.5 1 0 0 1 1 1 0 Variant UBP zinc finger PAP_central PF04928.17 KND97207.1 - 7.5e-112 372.3 0.0 1.1e-111 371.7 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KND97207.1 - 1.6e-55 187.3 1.0 2e-55 187.0 0.1 1.6 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KND97207.1 - 2.1e-14 53.6 0.1 5.2e-14 52.3 0.1 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KND97207.1 - 0.005 16.9 0.1 0.065 13.3 0.0 2.4 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase Nrap_D2 PF17403.2 KND97207.1 - 0.0062 16.3 0.3 0.014 15.2 0.1 1.8 2 1 0 2 2 2 1 Nrap protein PAP/OAS-like domain Oxysterol_BP PF01237.18 KND97208.1 - 1.8e-86 290.3 0.6 1.5e-77 260.9 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein PI3_PI4_kinase PF00454.27 KND97209.1 - 2e-39 135.9 0.1 8e-39 133.9 0.1 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 KND97209.1 - 1.1e-15 57.3 2.3 2.8e-15 56.0 1.6 2.2 2 0 0 2 2 2 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.20 KND97209.1 - 0.00025 20.5 1.1 0.00088 18.7 1.1 1.9 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 KND97209.1 - 0.031 13.6 0.0 0.076 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) ELP6 PF09807.9 KND97211.1 - 0.025 14.0 0.5 0.5 9.7 0.1 2.5 2 0 0 2 2 2 0 Elongation complex protein 6 Sec10 PF07393.11 KND97212.1 - 7.5e-64 216.4 20.5 9.5e-64 216.0 20.5 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Iron_permease PF04120.12 KND97213.1 - 0.032 14.0 0.1 0.033 14.0 0.1 1.0 1 0 0 1 1 1 0 Low affinity iron permease Collagen PF01391.18 KND97216.1 - 6.5e-09 35.4 87.7 3e-06 26.9 36.6 3.7 1 1 2 3 3 3 2 Collagen triple helix repeat (20 copies) Flo11 PF10182.9 KND97216.1 - 1.4e-06 28.5 0.0 2.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Flo11 domain Cpn60_TCP1 PF00118.24 KND97219.1 - 4.5e-157 523.6 4.0 5.2e-157 523.4 4.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PNTB_4TM PF12769.7 KND97219.1 - 0.17 12.4 0.0 0.42 11.1 0.0 1.6 1 0 0 1 1 1 0 4TM region of pyridine nucleotide transhydrogenase, mitoch LD_cluster2 PF18163.1 KND97220.1 - 0.042 13.4 0.1 0.045 13.3 0.1 1.0 1 0 0 1 1 1 0 SLOG cluster2 Cyclin_N PF00134.23 KND97222.1 - 3.1e-38 130.4 4.8 3.3e-38 130.3 0.8 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KND97222.1 - 5.7e-07 29.6 0.2 1.9e-06 28.0 0.2 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain zf-C2H2_8 PF15909.5 KND97222.1 - 0.4 11.0 3.4 11 6.3 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc ribbon Myosin_head PF00063.21 KND97223.1 - 7.3e-259 860.6 11.8 7.3e-259 860.6 11.8 2.0 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_N PF02736.19 KND97223.1 - 0.001 18.9 1.0 0.003 17.4 1.0 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KND97223.1 - 0.47 10.7 0.0 0.47 10.7 0.0 4.2 5 0 0 5 5 5 0 AAA domain AAA_16 PF13191.6 KND97223.1 - 1.7 9.0 0.0 1.7 9.0 0.0 4.4 3 1 0 4 4 4 0 AAA ATPase domain Sugar_tr PF00083.24 KND97225.1 - 2.2e-39 135.6 14.3 3.4e-39 135.0 14.3 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND97225.1 - 2.3e-20 72.8 18.0 3.6e-20 72.2 18.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily PAP2 PF01569.21 KND97226.1 - 5.1e-21 74.9 2.5 5.1e-21 74.9 2.5 1.9 2 0 0 2 2 2 1 PAP2 superfamily S-AdoMet_synt_C PF02773.16 KND97228.1 - 1.7e-66 222.4 0.2 4.1e-66 221.2 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KND97228.1 - 1.1e-45 154.8 0.0 2e-45 153.9 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KND97228.1 - 2.5e-44 150.0 0.1 5.3e-44 148.9 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 KND97228.1 - 0.021 13.6 0.1 0.12 11.2 0.1 2.0 1 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) MRC1 PF09444.10 KND97230.1 - 1.5e-35 122.9 21.5 1.5e-35 122.9 21.5 9.1 5 3 4 9 9 9 2 MRC1-like domain RPW8 PF05659.11 KND97231.1 - 0.19 11.4 1.1 0.57 9.9 0.4 2.0 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 KH_8 PF17903.1 KND97233.1 - 6e-32 109.6 0.2 1.6e-31 108.2 0.0 1.9 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 KND97233.1 - 0.022 14.6 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 KH domain TMIE PF16038.5 KND97234.1 - 0.013 15.3 2.3 0.13 12.2 0.1 2.1 2 0 0 2 2 2 0 TMIE protein DASH_Dam1 PF08653.10 KND97234.1 - 0.052 13.4 0.2 0.088 12.6 0.2 1.5 1 0 0 1 1 1 0 DASH complex subunit Dam1 Fmp27_WPPW PF10359.9 KND97234.1 - 0.058 12.2 7.6 0.063 12.1 7.6 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Csm2_III-A PF03750.13 KND97234.1 - 0.099 13.5 5.1 0.12 13.2 5.1 1.1 1 0 0 1 1 1 0 Csm2 Type III-A BshC PF10079.9 KND97234.1 - 0.33 9.7 8.7 0.35 9.5 8.7 1.0 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC BLOC1_2 PF10046.9 KND97234.1 - 0.47 10.8 8.2 0.074 13.4 1.9 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SecD-TM1 PF13721.6 KND97234.1 - 1.1 9.7 4.3 0.67 10.4 2.0 1.7 1 1 1 2 2 2 0 SecD export protein N-terminal TM region AAA_23 PF13476.6 KND97234.1 - 1.4 9.4 8.2 1.7 9.1 8.2 1.1 1 0 0 1 1 1 0 AAA domain V-SNARE PF05008.15 KND97234.1 - 1.6 9.1 12.0 1.5 9.3 1.9 2.8 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF1515 PF07439.11 KND97234.1 - 1.7 8.7 5.9 1 9.4 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) XhlA PF10779.9 KND97234.1 - 2.3 8.5 10.1 0.4 10.9 2.4 2.2 1 1 1 2 2 2 0 Haemolysin XhlA TMPIT PF07851.13 KND97234.1 - 7 5.8 8.5 8.4 5.5 8.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein ANAPC4_WD40 PF12894.7 KND97235.1 - 1.4e-08 34.9 0.9 0.0054 17.0 0.1 4.8 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KND97235.1 - 4.4e-08 33.6 7.4 4.1 8.4 0.0 7.4 8 0 0 8 8 8 3 WD domain, G-beta repeat PQQ PF01011.21 KND97235.1 - 2.4e-05 24.0 0.1 0.16 11.9 0.0 3.5 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.6 KND97235.1 - 0.00092 18.9 0.8 0.026 14.1 0.2 2.8 1 1 2 3 3 3 2 PQQ-like domain PQQ_3 PF13570.6 KND97235.1 - 0.15 12.6 7.3 4.8 7.8 0.0 5.5 7 0 0 7 7 7 0 PQQ-like domain DNA_primase_S PF01896.19 KND97237.1 - 2.2e-64 216.7 0.6 3.2e-64 216.2 0.6 1.2 1 0 0 1 1 1 1 DNA primase small subunit DUF3864 PF12980.7 KND97237.1 - 0.11 12.8 0.1 0.28 11.5 0.1 1.7 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3864) Cellulase PF00150.18 KND97238.1 - 3e-17 63.0 0.1 1.3e-07 31.4 0.0 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 KND97238.1 - 5.6e-08 33.2 0.0 1.3e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_35 PF01301.19 KND97238.1 - 0.05 13.2 0.2 0.092 12.4 0.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 HA2 PF04408.23 KND97240.1 - 1.4e-23 83.2 0.1 1.4e-22 80.0 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KND97240.1 - 7.5e-16 58.3 0.0 1.8e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KND97240.1 - 8.9e-13 48.6 0.0 2.1e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KND97240.1 - 7.3e-11 42.3 0.4 2.2e-10 40.7 0.1 2.0 2 0 0 2 2 1 1 S1 RNA binding domain DEAD PF00270.29 KND97240.1 - 8.6e-07 28.9 0.3 2e-06 27.7 0.3 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KND97240.1 - 6.8e-05 23.2 0.0 0.00025 21.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain W2 PF02020.18 KND97240.1 - 0.00091 19.3 0.1 0.61 10.3 0.0 2.6 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon AAA_30 PF13604.6 KND97240.1 - 0.002 17.9 0.4 0.0046 16.7 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KND97240.1 - 0.0026 17.8 0.2 0.14 12.2 0.2 2.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KND97240.1 - 0.0044 17.5 0.1 0.34 11.4 0.1 2.8 1 1 0 1 1 1 1 ABC transporter AAA_19 PF13245.6 KND97240.1 - 0.012 15.9 0.1 0.029 14.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KND97240.1 - 0.017 14.2 0.0 0.034 13.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 KND97240.1 - 0.021 14.2 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 KaiC Microtub_bd PF16796.5 KND97240.1 - 0.026 14.4 0.0 1.6 8.7 0.0 2.7 2 0 0 2 2 2 0 Microtubule binding SRP54 PF00448.22 KND97240.1 - 0.061 13.0 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PhoH PF02562.16 KND97240.1 - 0.064 12.7 0.0 0.16 11.4 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.22 KND97240.1 - 0.088 12.0 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ResIII PF04851.15 KND97240.1 - 0.11 12.5 0.0 5.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-PHD-like PF15446.6 KND97240.1 - 0.12 12.0 0.1 0.25 10.9 0.1 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Proteasome PF00227.26 KND97241.1 - 3e-34 118.2 0.0 3.4e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF4954 PF16314.5 KND97241.1 - 0.039 12.1 0.0 0.048 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Herpes_UL3 PF03369.13 KND97241.1 - 0.11 13.0 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL3 protein Lum_binding PF00677.17 KND97242.1 - 3.8e-41 139.0 5.1 6.8e-20 70.8 1.1 2.3 2 0 0 2 2 2 2 Lumazine binding domain DUF4834 PF16118.5 KND97247.1 - 0.037 15.0 0.1 0.038 15.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) QCR10 PF09796.9 KND97249.1 - 2.6 8.2 5.0 3.3 7.8 4.5 1.4 1 1 1 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) LicD PF04991.13 KND97250.1 - 1e-27 97.8 5.6 7.4e-26 91.7 0.1 3.3 2 1 1 3 3 3 2 LicD family Phytase PF02333.15 KND97250.1 - 0.0064 15.5 0.1 0.0097 14.9 0.1 1.2 1 0 0 1 1 1 1 Phytase Thiolase_N PF00108.23 KND97253.1 - 2.1e-85 286.2 1.5 2.1e-85 286.2 1.5 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KND97253.1 - 5.2e-46 155.3 0.5 1.1e-45 154.3 0.5 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KND97253.1 - 6.2e-06 26.0 1.4 7.2e-05 22.5 0.1 2.7 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain SelA PF03841.13 KND97253.1 - 0.029 13.4 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase RWD PF05773.22 KND97256.1 - 0.0013 19.0 1.4 1.4 9.2 0.1 3.4 2 1 1 3 3 3 2 RWD domain DUF4288 PF14119.6 KND97256.1 - 0.072 13.5 0.7 13 6.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) MFS_1 PF07690.16 KND97259.1 - 2e-11 43.4 39.4 5.7e-10 38.7 39.4 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Pam17 PF08566.10 KND97259.1 - 0.027 14.3 1.0 0.064 13.1 0.2 2.1 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 His_Phos_2 PF00328.22 KND97262.1 - 5.9e-50 170.7 0.0 7e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF4228 PF14009.6 KND97264.1 - 0.037 14.4 0.2 0.076 13.4 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Drc1-Sld2 PF11719.8 KND97264.1 - 0.15 11.5 2.1 0.21 11.1 2.1 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein UPF0121 PF03661.13 KND97265.1 - 0.0099 15.3 9.7 0.021 14.3 9.7 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) TPR_8 PF13181.6 KND97266.1 - 1.3e-06 28.1 6.7 0.18 12.1 0.3 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KND97266.1 - 4.8e-06 26.3 7.8 0.23 11.7 0.2 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KND97266.1 - 5.6e-05 23.6 7.6 2.4 9.2 0.0 5.6 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KND97266.1 - 7.8e-05 22.3 4.7 0.11 12.4 0.2 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KND97266.1 - 0.0069 17.0 2.8 2.3 8.9 0.0 4.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KND97266.1 - 0.014 15.8 0.0 0.014 15.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KND97266.1 - 0.043 14.1 5.0 0.89 9.9 0.5 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KND97266.1 - 0.35 11.1 5.5 5 7.4 0.5 2.9 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KND97266.1 - 1.3 9.2 4.3 58 4.1 0.1 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 KND97266.1 - 2.2 8.8 8.7 1.1 9.8 0.2 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.25 KND97267.1 - 5.2e-40 137.5 0.0 9.4e-40 136.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND97267.1 - 5.3e-26 91.4 0.0 8.2e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KND97267.1 - 5e-06 26.0 0.1 2e-05 24.1 0.1 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KND97267.1 - 5.8e-05 22.2 1.4 0.00022 20.3 0.1 2.4 2 1 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KND97267.1 - 0.029 13.1 0.1 0.029 13.1 0.1 2.2 2 0 0 2 2 2 0 Fungal protein kinase ORC2 PF04084.14 KND97268.1 - 2.8e-99 332.2 0.1 3.9e-99 331.7 0.1 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 TFIIS_C PF01096.18 KND97269.1 - 6.3e-22 77.1 5.3 1.6e-21 75.9 2.4 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.7 KND97269.1 - 0.0015 18.5 0.9 0.058 13.4 0.3 2.3 2 0 0 2 2 2 1 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 KND97269.1 - 0.0017 18.3 1.5 0.17 11.9 0.2 2.3 2 0 0 2 2 2 2 PhnA Zinc-Ribbon zinc_ribbon_4 PF13717.6 KND97269.1 - 0.0094 15.9 6.0 0.11 12.4 0.4 2.7 3 0 0 3 3 3 2 zinc-ribbon domain RNA_POL_M_15KD PF02150.16 KND97269.1 - 0.067 13.1 3.8 0.081 12.8 0.0 2.5 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit zf-H2C2_2 PF13465.6 KND97269.1 - 0.59 10.7 6.0 0.97 10.0 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger double domain Lactamase_B_2 PF12706.7 KND97270.1 - 8.3e-05 22.2 0.0 0.00045 19.8 0.0 2.1 2 1 0 2 2 2 1 Beta-lactamase superfamily domain PDEase_II PF02112.15 KND97270.1 - 0.21 10.7 1.0 0.3 10.1 0.1 1.6 2 0 0 2 2 2 0 cAMP phosphodiesterases class-II RRM_1 PF00076.22 KND97271.1 - 0.0031 17.3 0.8 0.019 14.8 0.1 2.7 3 1 1 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATC_hydrolase PF14196.6 KND97271.1 - 0.73 10.6 4.1 11 6.7 0.6 2.5 2 1 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase OSTbeta PF15048.6 KND97271.1 - 1 9.5 4.9 0.14 12.3 0.7 1.7 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein DUF2428 PF10350.9 KND97272.1 - 8.7e-38 130.1 0.0 1.8e-37 129.1 0.0 1.5 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT_2 PF13646.6 KND97272.1 - 0.00027 21.3 0.3 1.1 9.7 0.0 4.4 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 KND97272.1 - 0.087 13.1 6.9 6.6 7.3 0.0 5.1 4 0 0 4 4 4 0 HEAT repeat MFS_1 PF07690.16 KND97273.1 - 1.3e-14 53.9 29.6 4.8e-12 45.5 29.2 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Patatin PF01734.22 KND97273.1 - 0.18 12.0 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Patatin-like phospholipase Thy1 PF02511.15 KND97275.1 - 0.097 12.5 0.0 0.099 12.4 0.0 1.0 1 0 0 1 1 1 0 Thymidylate synthase complementing protein MtrF PF09472.10 KND97277.1 - 0.13 11.7 1.8 0.14 11.6 1.8 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) SNF2_N PF00176.23 KND97278.1 - 1.1e-52 178.9 0.0 1.7e-52 178.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KND97278.1 - 1.5e-13 51.1 0.0 1.2e-12 48.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND97278.1 - 3e-13 50.1 0.0 6.3e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KND97278.1 - 1.2e-06 28.4 0.0 2.3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase bVLRF1 PF18826.1 KND97279.1 - 3.3e-61 205.5 0.6 6.8e-61 204.5 0.6 1.5 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank PF00023.30 KND97279.1 - 0.0022 18.4 0.1 0.0052 17.2 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 KND97279.1 - 0.0027 18.0 0.0 0.0055 17.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KND97279.1 - 0.0045 17.6 0.1 0.0087 16.6 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND97279.1 - 0.066 13.8 0.0 0.17 12.5 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat URO-D PF01208.17 KND97281.1 - 2e-112 375.8 0.0 2.5e-112 375.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF1818 PF08848.11 KND97281.1 - 0.088 12.9 0.0 0.21 11.7 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1818) Peptidase_M28 PF04389.17 KND97282.1 - 2e-39 135.4 0.0 4.1e-39 134.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 KND97282.1 - 0.0073 15.3 0.0 0.028 13.4 0.0 1.8 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 KND97282.1 - 0.026 14.2 0.0 0.031 14.0 0.0 1.5 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 Pkinase PF00069.25 KND97284.1 - 5.9e-67 225.8 0.0 7e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND97284.1 - 2.3e-38 132.0 0.0 2.8e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND97284.1 - 1.4e-06 27.9 0.0 4.4e-06 26.2 0.0 1.8 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KND97284.1 - 0.00026 19.9 0.0 0.00039 19.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KND97284.1 - 0.0046 16.3 0.0 0.0074 15.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KND97284.1 - 0.091 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL SCA7 PF08313.12 KND97285.1 - 1.7e-30 104.7 0.5 6e-30 102.9 0.5 2.0 1 0 0 1 1 1 1 SCA7, zinc-binding domain DDHD PF02862.17 KND97285.1 - 0.54 10.4 16.0 1.4 9.0 4.9 2.3 2 0 0 2 2 2 0 DDHD domain UPF0565 PF10561.9 KND97285.1 - 0.82 8.8 7.5 2.8 7.1 0.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 TAF4 PF05236.14 KND97285.1 - 1.6 8.4 34.0 0.71 9.6 7.6 2.5 2 1 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family CCSAP PF15748.5 KND97285.1 - 1.7 8.8 29.6 2.7 8.1 8.7 2.3 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Bacteriocin_IIi PF11758.8 KND97287.1 - 0.026 14.3 0.2 0.088 12.7 0.2 1.9 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin WD40 PF00400.32 KND97287.1 - 0.13 13.2 0.4 1.2 10.1 0.1 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat SSP160 PF06933.11 KND97288.1 - 2.9 6.0 4.6 3.1 5.9 4.6 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 HIG_1_N PF04588.13 KND97289.1 - 1.9e-05 24.8 1.0 3.2e-05 24.1 0.1 1.8 2 0 0 2 2 2 1 Hypoxia induced protein conserved region Med19 PF10278.9 KND97289.1 - 0.55 10.1 12.5 0.94 9.4 12.5 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 BBS2_N PF14781.6 KND97290.1 - 0.032 14.1 0.7 0.032 14.1 0.7 1.0 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal Pex24p PF06398.11 KND97292.1 - 4.4e-75 253.0 14.1 5.2e-75 252.7 14.1 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Cgr1 PF03879.14 KND97293.1 - 5.6e-29 100.7 32.4 6.7e-29 100.4 32.4 1.1 1 0 0 1 1 1 1 Cgr1 family DUF2048 PF09752.9 KND97293.1 - 0.85 8.7 5.2 1.1 8.3 5.2 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 LMBR1 PF04791.16 KND97293.1 - 6 5.7 5.1 6 5.6 5.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein TBP PF00352.21 KND97294.1 - 3.2e-68 225.7 0.1 8e-33 112.3 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KND97294.1 - 2.6e-05 24.3 0.0 0.2 11.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KND97294.1 - 0.1 12.4 0.2 0.61 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Exo_endo_phos PF03372.23 KND97295.1 - 4.7e-13 49.2 0.0 8.8e-13 48.3 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 KND97295.1 - 2.6e-07 30.6 4.2 6.1e-07 29.4 4.2 1.7 1 0 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 KND97295.1 - 0.00036 20.4 0.0 0.89 9.4 0.0 2.4 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase SOGA PF11365.8 KND97296.1 - 7.3 7.8 14.7 0.99 10.6 1.2 3.5 3 0 0 3 3 3 0 Protein SOGA Cohesin_load PF10345.9 KND97297.1 - 3.5e-65 220.6 19.3 4.4e-65 220.3 19.3 1.0 1 0 0 1 1 1 1 Cohesin loading factor SNAP PF14938.6 KND97297.1 - 0.0055 16.2 3.9 0.017 14.6 2.5 2.2 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP RPN7 PF10602.9 KND97297.1 - 0.038 13.7 0.1 0.34 10.6 0.0 2.6 2 1 0 3 3 3 0 26S proteasome subunit RPN7 TPR_12 PF13424.6 KND97297.1 - 0.96 9.8 7.4 0.88 9.9 0.4 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KND97297.1 - 2.6 8.5 4.4 6 7.4 1.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat UEV PF05743.13 KND97298.1 - 1.8e-18 66.6 0.0 3.3e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KND97298.1 - 3e-16 59.1 0.2 9.9e-16 57.4 0.0 1.9 2 0 0 2 2 2 1 Vps23 core domain Lectin_N PF03954.14 KND97298.1 - 0.79 9.5 5.7 5.3 6.8 0.7 2.4 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Phage_GPO PF05929.11 KND97298.1 - 0.83 9.2 3.4 1.4 8.5 3.4 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Sec34 PF04136.15 KND97298.1 - 0.94 9.4 5.6 1.7 8.6 5.6 1.3 1 0 0 1 1 1 0 Sec34-like family UPF0242 PF06785.11 KND97298.1 - 1.7 8.7 11.3 0.93 9.6 9.0 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 KND97298.1 - 2.4 8.3 6.4 4.7 7.4 6.4 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family AA_permease PF00324.21 KND97302.1 - 2.3e-112 376.0 41.3 2.8e-112 375.8 41.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND97302.1 - 1.7e-31 109.5 45.1 2.1e-31 109.2 45.1 1.1 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.22 KND97303.1 - 8.9e-38 130.2 0.0 8.1e-37 127.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 ERO1 PF04137.15 KND97304.1 - 3.2e-117 391.7 0.0 3.9e-117 391.4 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Flocculin_t3 PF13928.6 KND97305.1 - 5.5e-11 42.8 23.3 5.5e-11 42.8 23.3 3.1 2 1 0 2 2 2 1 Flocculin type 3 repeat DUF1924 PF09086.11 KND97305.1 - 0.22 11.9 1.0 0.37 11.2 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1924) GCHY-1 PF02649.14 KND97305.1 - 0.24 10.9 1.3 0.38 10.2 1.3 1.2 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 Arch_flagellin PF01917.16 KND97305.1 - 0.28 11.3 8.3 0.087 13.0 4.8 1.8 2 0 0 2 2 2 0 Archaebacterial flagellin Fungal_trans_2 PF11951.8 KND97306.1 - 6.9e-95 318.1 0.5 9.3e-95 317.7 0.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND97306.1 - 1.8e-09 37.6 6.9 3e-09 36.8 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dak1 PF02733.17 KND97308.1 - 2.6e-101 338.6 0.7 3.7e-101 338.1 0.7 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KND97308.1 - 4.8e-48 163.3 2.3 4.8e-48 163.3 2.3 2.3 2 0 0 2 2 2 1 DAK2 domain Pyr_redox_2 PF07992.14 KND97309.1 - 2.7e-08 33.4 0.1 0.13 11.4 0.0 4.2 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KND97309.1 - 2.3e-06 27.0 0.0 6.7e-05 22.2 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KND97309.1 - 0.00029 20.5 2.4 0.33 10.5 0.0 3.5 3 1 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KND97309.1 - 0.0014 17.9 0.9 4.7 6.4 0.7 4.2 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KND97309.1 - 0.0014 18.6 0.1 0.46 10.5 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KND97309.1 - 0.0031 18.0 2.5 1.3 9.7 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KND97309.1 - 0.0071 15.4 0.3 0.23 10.5 0.2 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KND97309.1 - 0.15 11.3 0.0 0.44 9.8 0.0 1.7 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 KND97309.1 - 0.21 10.8 3.6 3.4 6.8 0.5 2.8 3 0 0 3 3 3 0 FAD binding domain NAD_binding_8 PF13450.6 KND97309.1 - 0.22 11.8 1.8 6.2 7.1 0.0 2.8 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain RACo_linker PF17650.1 KND97311.1 - 0.056 13.3 0.0 0.056 13.3 0.0 1.0 1 0 0 1 1 1 0 RACo linker region Rtt106 PF08512.12 KND97311.1 - 0.12 12.8 0.0 0.12 12.8 0.0 1.1 1 0 0 1 1 1 0 Histone chaperone Rttp106-like Packaging_FI PF14000.6 KND97313.1 - 0.19 12.2 0.2 18 5.8 0.0 2.6 2 0 0 2 2 2 0 DNA packaging protein FI Fungal_trans_2 PF11951.8 KND97314.1 - 7.7e-41 140.2 0.0 1e-40 139.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND97314.1 - 0.00016 21.7 9.5 0.00032 20.8 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_9 PF13901.6 KND97314.1 - 0.26 11.3 2.4 1.8 8.5 2.3 2.0 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Arrestin_N PF00339.29 KND97320.1 - 2.4e-08 34.2 0.6 2.7e-07 30.7 0.6 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain MFS_1 PF07690.16 KND97322.1 - 1.6e-17 63.5 45.0 8.3e-11 41.4 34.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily S1FA PF04689.13 KND97322.1 - 0.017 15.2 0.0 0.052 13.7 0.0 1.9 1 0 0 1 1 1 0 DNA binding protein S1FA DUF4293 PF14126.6 KND97322.1 - 0.8 9.9 5.7 2 8.7 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4293) Pox_A14 PF05767.12 KND97322.1 - 3.5 7.9 8.8 0.41 10.8 0.1 3.5 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 Zip PF02535.22 KND97323.1 - 1.7e-50 172.1 17.9 2.7e-50 171.5 17.9 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Thyroglobulin_1 PF00086.18 KND97323.1 - 1 9.1 3.0 1.1e+02 2.6 0.0 3.6 4 0 0 4 4 4 0 Thyroglobulin type-1 repeat DUF959 PF06121.14 KND97327.1 - 0.71 10.1 12.6 18 5.5 0.0 2.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF959) TFIIF_alpha PF05793.12 KND97327.1 - 1.2 7.7 9.5 1.6 7.2 9.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RAP1 PF07218.11 KND97327.1 - 4.9 5.3 8.9 5.3 5.2 8.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AJAP1_PANP_C PF15298.6 KND97327.1 - 5.2 7.2 9.3 0.56 10.4 2.7 2.0 2 0 0 2 2 2 0 AJAP1/PANP C-terminus tRNA-synt_1_2 PF13603.6 KND97328.1 - 0.019 14.5 0.1 0.038 13.5 0.1 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 CRAL_TRIO PF00650.20 KND97329.1 - 1.3e-26 93.3 1.1 1.8e-26 92.8 0.6 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KND97329.1 - 6.7e-06 26.3 0.3 1.1e-05 25.6 0.3 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain GGDEF_2 PF17853.1 KND97330.1 - 0.02 15.1 0.4 0.038 14.3 0.4 1.5 1 1 0 1 1 1 0 GGDEF-like domain FAD_binding_8 PF08022.12 KND97331.1 - 1.8e-18 66.6 0.0 4.2e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KND97331.1 - 1.7e-17 63.7 3.8 1.7e-17 63.7 3.8 2.1 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KND97331.1 - 2.4e-17 63.5 0.0 3.8e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KND97331.1 - 0.19 12.4 0.0 0.41 11.3 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Glyco_transf_21 PF13506.6 KND97332.1 - 2e-17 63.2 0.1 7.7e-13 48.3 0.1 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KND97332.1 - 7.3e-11 42.4 0.0 1.2e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KND97332.1 - 0.00042 20.2 0.1 0.0038 17.0 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 2 DUF4131 PF13567.6 KND97332.1 - 1.4 8.5 8.3 0.64 9.6 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Clusterin PF01093.17 KND97333.1 - 0.0029 16.7 0.1 0.0029 16.7 0.1 1.0 1 0 0 1 1 1 1 Clusterin Carn_acyltransf PF00755.20 KND97334.1 - 2.6e-186 620.7 0.0 3e-186 620.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ATG11 PF10377.9 KND97335.1 - 2.3e-36 124.7 0.1 2.3e-36 124.7 0.1 3.5 3 1 1 4 4 4 1 Autophagy-related protein 11 TPR_MLP1_2 PF07926.12 KND97335.1 - 0.36 10.9 42.6 0.058 13.5 17.4 4.3 3 1 0 4 4 4 0 TPR/MLP1/MLP2-like protein Mce4_CUP1 PF11887.8 KND97335.1 - 0.6 9.5 3.4 1.5 8.2 0.0 3.3 5 0 0 5 5 5 0 Cholesterol uptake porter CUP1 of Mce4, putative Spc7 PF08317.11 KND97335.1 - 0.7 8.7 46.3 0.49 9.2 16.7 3.9 2 1 1 3 3 3 0 Spc7 kinetochore protein HALZ PF02183.18 KND97335.1 - 0.91 9.8 31.9 0.28 11.4 1.2 5.6 5 0 0 5 5 5 0 Homeobox associated leucine zipper Pribosyltran_N PF13793.6 KND97336.1 - 2.1e-41 140.5 0.2 1.9e-39 134.2 0.0 2.3 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KND97336.1 - 1.8e-39 135.7 0.5 3.8e-36 124.8 0.3 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KND97336.1 - 1.6e-17 63.5 0.3 3.7e-17 62.3 0.3 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KND97336.1 - 0.0023 17.4 0.1 0.0042 16.6 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase ILVD_EDD PF00920.21 KND97337.1 - 7.2e-211 701.3 0.0 8.4e-211 701.1 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family HMGL-like PF00682.19 KND97339.1 - 5.1e-84 281.9 0.1 7.3e-84 281.4 0.1 1.2 1 0 0 1 1 1 1 HMGL-like EXS PF03124.14 KND97341.1 - 5.3e-98 328.4 28.4 7e-98 328.0 28.4 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KND97341.1 - 5.6e-53 181.2 28.9 3.1e-40 139.3 11.2 3.0 2 1 1 3 3 3 2 SPX domain Abhydrolase_6 PF12697.7 KND97342.1 - 2.6e-20 74.0 0.0 4e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KND97342.1 - 5.5e-17 62.3 0.0 1.8e-16 60.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KND97342.1 - 1.5e-10 40.8 0.0 3.9e-10 39.4 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DSPc PF00782.20 KND97342.1 - 2.1e-09 37.3 0.0 1.1e-08 35.0 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain LIDHydrolase PF10230.9 KND97342.1 - 8e-08 32.2 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 KND97342.1 - 1.5e-06 28.1 0.1 4.9e-06 26.4 0.1 1.8 1 1 0 1 1 1 1 PGAP1-like protein Chlorophyllase2 PF12740.7 KND97342.1 - 0.00076 18.5 0.0 0.0015 17.5 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF900 PF05990.12 KND97342.1 - 0.002 17.7 0.1 0.0053 16.3 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.13 KND97342.1 - 0.0026 17.7 0.0 0.0062 16.4 0.0 1.6 1 0 0 1 1 1 1 Serine hydrolase Y_phosphatase PF00102.27 KND97342.1 - 0.004 16.7 0.1 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase BAAT_C PF08840.11 KND97342.1 - 0.013 15.4 0.0 0.3 11.0 0.0 2.2 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PTPlike_phytase PF14566.6 KND97342.1 - 0.026 14.7 0.0 0.093 12.8 0.0 1.9 1 0 0 1 1 1 0 Inositol hexakisphosphate Abhydrolase_2 PF02230.16 KND97342.1 - 0.026 14.3 0.1 10 5.9 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KND97342.1 - 0.026 14.4 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KND97342.1 - 0.059 13.1 0.0 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family LCAT PF02450.15 KND97342.1 - 0.11 11.7 0.0 0.37 9.9 0.0 1.8 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Thioesterase PF00975.20 KND97342.1 - 0.12 12.5 0.0 16 5.5 0.0 2.3 2 0 0 2 2 2 0 Thioesterase domain DUF3089 PF11288.8 KND97342.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Y_phosphatase3 PF13350.6 KND97342.1 - 0.2 11.6 0.0 0.5 10.3 0.0 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family PhoLip_ATPase_C PF16212.5 KND97343.1 - 1.8e-49 168.8 15.3 1.8e-49 168.8 15.3 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KND97343.1 - 9.2e-20 70.1 1.5 2.2e-19 68.9 1.5 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 KND97343.1 - 5.1e-13 48.9 3.7 5.9e-13 48.7 0.1 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KND97343.1 - 1.2e-10 42.1 1.3 9.7e-06 26.0 0.4 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KND97343.1 - 5e-09 36.1 0.0 2.1e-07 30.9 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KND97343.1 - 0.0067 16.2 0.2 0.028 14.2 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ATP-synt_ab PF00006.25 KND97347.1 - 5e-73 245.3 0.0 6.9e-73 244.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KND97347.1 - 1.1e-49 167.9 0.7 1.7e-49 167.3 0.7 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ETS_PEA3_N PF04621.13 KND97348.1 - 1.3 8.9 12.9 2.2e+02 1.5 12.9 2.2 1 1 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain GREB1 PF15782.5 KND97348.1 - 3 4.9 16.4 3.8 4.5 16.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peptidase_M1 PF01433.20 KND97350.1 - 1.8e-85 286.0 1.5 2.8e-85 285.3 1.5 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KND97350.1 - 1.3e-79 268.0 1.4 4e-78 263.1 0.7 2.3 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KND97350.1 - 1.4e-50 172.1 0.6 2.2e-50 171.5 0.1 1.6 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 KND97350.1 - 0.0073 16.3 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2808) Rhodanese PF00581.20 KND97351.1 - 1.5e-07 31.9 0.0 1.9e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Rotamase PF00639.21 KND97352.1 - 9.6e-21 74.6 0.0 1.4e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KND97352.1 - 4.9e-17 62.5 0.0 7.3e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KND97352.1 - 1.4e-09 37.9 3.8 2.4e-09 37.1 3.8 1.4 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 KND97352.1 - 5.5e-07 30.4 0.0 8.1e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain X8 PF07983.13 KND97352.1 - 0.19 12.5 0.0 0.19 12.5 0.0 1.6 2 0 0 2 2 2 0 X8 domain ADK PF00406.22 KND97353.1 - 5.8e-45 153.1 0.0 7.6e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KND97353.1 - 2.7e-34 118.5 0.0 3.7e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KND97353.1 - 1.6e-08 35.2 0.0 2.6e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KND97353.1 - 4e-05 23.8 0.0 9.2e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 KND97353.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 KND97353.1 - 0.18 11.1 0.1 0.51 9.6 0.1 1.9 1 1 0 1 1 1 0 Zeta toxin Ploopntkinase3 PF18751.1 KND97353.1 - 0.19 11.6 0.0 0.37 10.7 0.0 1.5 1 1 0 1 1 1 0 P-loop Nucleotide Kinase3 Thymidylate_kin PF02223.17 KND97353.1 - 0.21 11.2 2.2 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase adh_short PF00106.25 KND97354.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Pan3_PK PF18101.1 KND97355.1 - 5e-39 133.4 0.4 9.7e-39 132.5 0.4 1.4 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KND97355.1 - 0.00011 21.7 0.0 0.00026 20.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Cyclin_N PF00134.23 KND97356.1 - 1.6e-05 24.7 0.4 2.4e-05 24.1 0.4 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Telomere_reg-2 PF10193.9 KND97356.1 - 0.084 13.3 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 Telomere length regulation protein NAP PF00956.18 KND97358.1 - 3.6e-95 318.2 15.0 3.6e-95 318.2 15.0 1.6 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) BSP_II PF05432.11 KND97358.1 - 0.001 18.8 9.4 0.001 18.8 9.4 3.4 3 1 1 4 4 4 1 Bone sialoprotein II (BSP-II) Afaf PF15339.6 KND97358.1 - 0.23 11.1 2.9 0.98 9.1 2.4 2.3 2 0 0 2 2 2 0 Acrosome formation-associated factor Spot_14 PF07084.12 KND97358.1 - 0.65 10.1 8.3 0.36 10.9 2.2 2.6 2 0 0 2 2 2 0 Thyroid hormone-inducible hepatic protein Spot 14 ABC_membrane_2 PF06472.15 KND97359.1 - 8.4e-87 291.0 6.4 1.5e-86 290.2 6.4 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KND97359.1 - 5.3e-18 65.8 0.0 1.8e-17 64.1 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 KND97359.1 - 3.3e-06 27.7 1.1 3.3e-06 27.7 1.1 2.3 3 1 0 3 3 3 1 AAA domain SMC_N PF02463.19 KND97359.1 - 0.0096 15.4 0.1 3.3 7.1 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 KND97359.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 KND97359.1 - 0.07 13.5 0.0 0.32 11.4 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KND97359.1 - 0.075 13.0 0.1 0.79 9.7 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) MFS_1 PF07690.16 KND97361.1 - 3.1e-38 131.6 18.6 3.1e-38 131.6 18.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily RseC_MucC PF04246.12 KND97361.1 - 0.37 10.8 7.3 7 6.6 0.0 3.8 3 1 1 4 4 4 0 Positive regulator of sigma(E), RseC/MucC UPF0203 PF05254.12 KND97363.1 - 5.7e-06 26.5 2.5 8.9e-06 25.9 2.5 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) CX9C PF16860.5 KND97363.1 - 0.00015 21.7 1.8 0.0082 16.1 0.1 2.3 1 1 1 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KND97363.1 - 0.0021 18.0 2.4 0.081 13.0 0.6 1.9 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 KND97363.1 - 0.0031 17.6 3.0 0.009 16.1 0.8 2.0 1 1 1 2 2 2 1 CHCH domain UCR_hinge PF02320.16 KND97363.1 - 0.009 16.2 0.5 0.011 16.0 0.5 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein NDUF_B7 PF05676.13 KND97363.1 - 0.03 14.0 0.6 0.034 13.9 0.6 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX17 PF05051.13 KND97363.1 - 0.039 14.3 1.4 0.18 12.2 1.4 1.8 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Ndufs5 PF10200.9 KND97363.1 - 0.04 14.2 0.1 0.042 14.1 0.1 1.1 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Mito_carr PF00153.27 KND97364.1 - 6.8e-55 183.0 3.7 2e-17 62.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CBS PF00571.28 KND97365.1 - 0.059 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 CBS domain M16C_assoc PF08367.11 KND97367.1 - 3.4e-69 232.8 0.4 5.1e-69 232.2 0.4 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KND97367.1 - 2.6e-14 53.6 0.6 9e-11 42.1 0.1 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KND97367.1 - 2.7e-08 33.9 1.9 1.3e-06 28.4 0.0 3.4 3 1 0 3 3 3 1 Insulinase (Peptidase family M16) Peripla_BP_7 PF18610.1 KND97367.1 - 0.19 11.9 1.2 13 6.0 0.1 3.0 3 0 0 3 3 3 0 Periplasmic binding protein domain Baculo_LEF5 PF04838.12 KND97367.1 - 0.52 10.3 4.3 7.7 6.5 0.2 2.7 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 Ribosomal_L33 PF00471.20 KND97368.1 - 0.00012 22.5 0.2 0.00018 21.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L33 EMP24_GP25L PF01105.24 KND97369.1 - 5.8e-37 127.4 0.0 6.9e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PPTA PF01239.22 KND97370.1 - 0.053 13.3 0.3 0.19 11.5 0.3 2.0 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat Rad33 PF08730.10 KND97371.1 - 4.1e-46 157.0 1.6 5.1e-46 156.7 1.6 1.1 1 0 0 1 1 1 1 Rad33 PALP PF00291.25 KND97372.1 - 5.9e-55 186.7 0.0 7e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DOT1 PF08123.13 KND97374.1 - 3.8e-73 245.4 0.1 6.1e-73 244.7 0.1 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 DUF2852 PF11014.8 KND97374.1 - 0.076 13.2 0.1 0.076 13.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) Resolvase PF00239.21 KND97374.1 - 0.24 11.5 4.2 0.56 10.3 4.2 1.6 1 0 0 1 1 1 0 Resolvase, N terminal domain SNF2_N PF00176.23 KND97375.1 - 2.4e-74 250.2 0.7 4.7e-74 249.2 0.7 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KND97375.1 - 7.9e-36 122.5 3.1 7.9e-36 122.5 3.1 3.1 4 0 0 4 4 4 1 SLIDE HAND PF09110.11 KND97375.1 - 5e-31 107.7 4.7 5e-31 107.7 4.7 4.0 4 0 0 4 4 4 1 HAND Helicase_C PF00271.31 KND97375.1 - 1e-19 70.9 0.0 1.1e-18 67.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND97375.1 - 9.2e-12 45.3 0.0 9.2e-12 45.3 0.0 3.5 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KND97375.1 - 6e-06 26.1 0.0 1.6e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KND97375.1 - 4.1e-05 23.4 0.6 0.0001 22.1 0.0 1.9 2 0 0 2 2 2 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 KND97375.1 - 0.012 14.8 2.0 0.015 14.6 0.1 2.0 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase ACP_PD PF04336.12 KND97375.1 - 0.098 13.1 1.7 0.32 11.4 1.7 1.9 1 0 0 1 1 1 0 Acyl carrier protein phosphodiesterase Agenet PF05641.12 KND97375.1 - 0.14 12.6 0.2 0.39 11.2 0.2 1.8 1 0 0 1 1 1 0 Agenet domain LRS4 PF10422.9 KND97375.1 - 0.44 10.1 8.2 0.27 10.8 5.1 2.2 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 UDG PF03167.19 KND97376.1 - 3.8e-16 59.5 0.1 7.8e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily OST3_OST6 PF04756.13 KND97377.1 - 6.7e-63 212.8 0.0 8e-63 212.5 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family EamA PF00892.20 KND97378.1 - 2.4e-13 50.4 36.0 3.9e-08 33.6 3.4 3.5 3 1 0 3 3 3 2 EamA-like transporter family DUF3955 PF13127.6 KND97378.1 - 0.0019 18.0 1.1 0.0019 18.0 1.1 4.5 4 0 0 4 4 4 1 Protein of unknown function (DUF3955) KRE9 PF05390.11 KND97379.1 - 9.3e-36 122.7 14.5 2.4e-35 121.4 14.5 1.7 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 KND97379.1 - 4.1e-18 65.9 0.8 4.1e-18 65.9 0.8 2.3 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family NAR2 PF16974.5 KND97379.1 - 0.0029 17.0 2.4 0.2 11.1 0.3 2.4 1 1 1 2 2 2 2 High-affinity nitrate transporter accessory DUF2369 PF10179.9 KND97379.1 - 0.019 15.4 3.5 0.044 14.2 3.5 1.7 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) DUF4458 PF14660.6 KND97379.1 - 0.045 14.0 0.2 0.11 12.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4458) KRE9 PF05390.11 KND97382.1 - 1.6e-24 86.5 12.8 2.8e-24 85.8 12.8 1.4 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 KND97382.1 - 3.3e-17 63.0 3.0 3.8e-17 62.8 0.2 2.2 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Big_5 PF13205.6 KND97382.1 - 0.021 15.5 2.0 0.028 15.1 0.1 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain Mgm101p PF06420.12 KND97384.1 - 3.8e-87 290.2 0.0 4.6e-87 289.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Tim17 PF02466.19 KND97385.1 - 0.11 12.9 2.7 0.33 11.4 2.6 1.6 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family MAS20 PF02064.15 KND97386.1 - 1.2e-37 128.9 0.5 1.5e-37 128.6 0.5 1.1 1 0 0 1 1 1 1 MAS20 protein import receptor SARAF PF06682.12 KND97386.1 - 0.16 11.6 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Cellulase PF00150.18 KND97387.1 - 1.7e-18 67.1 7.0 1.7e-18 67.1 7.0 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Homoserine_dh PF00742.19 KND97388.1 - 2.1e-51 174.3 0.0 3e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KND97388.1 - 1.2e-20 74.3 0.0 2.1e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KND97388.1 - 0.0002 21.8 0.0 0.00086 19.7 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KND97388.1 - 0.02 15.5 0.0 0.06 13.9 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KND97388.1 - 0.042 13.5 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KND97388.1 - 0.059 13.2 0.8 0.42 10.5 0.3 2.3 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KND97388.1 - 0.079 12.2 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KND97388.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KND97388.1 - 0.16 12.8 0.0 0.28 12.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold RNA_pol_L_2 PF13656.6 KND97388.1 - 0.18 11.6 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain IML1 PF12257.8 KND97389.1 - 1.6e-95 319.5 0.0 2.4e-95 318.9 0.0 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KND97389.1 - 5.7e-25 87.2 0.1 1.5e-24 85.8 0.1 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) SNO PF01174.19 KND97390.1 - 6.9e-58 195.6 0.0 2.6e-45 154.6 0.0 2.0 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 KND97390.1 - 7.8e-09 35.4 0.0 3.2e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 KND97390.1 - 0.00065 19.5 0.0 0.0022 17.8 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 KND97390.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 DJ-1_PfpI PF01965.24 KND97390.1 - 0.037 13.8 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family SOR_SNZ PF01680.17 KND97392.1 - 6.5e-103 342.9 1.2 8.5e-103 342.5 1.2 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KND97392.1 - 3.6e-11 42.8 1.5 9.7e-09 34.9 0.0 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 KND97392.1 - 0.00027 20.1 0.3 0.038 13.1 0.0 2.4 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 KND97392.1 - 0.0041 16.3 0.2 0.022 14.0 0.0 2.1 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase Ribosomal_S5_C PF03719.15 KND97392.1 - 0.0048 16.3 0.0 0.71 9.4 0.0 2.4 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain NMO PF03060.15 KND97392.1 - 0.0056 16.1 2.3 0.048 13.0 0.1 2.1 2 0 0 2 2 2 1 Nitronate monooxygenase TetR_C_27 PF17935.1 KND97392.1 - 0.019 15.0 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain IGPS PF00218.21 KND97392.1 - 0.066 12.4 0.0 0.92 8.6 0.0 2.2 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Peroxin-22 PF12827.7 KND97393.1 - 3.5e-28 97.8 0.2 4.8e-28 97.4 0.2 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis protein family RasGEF PF00617.19 KND97394.1 - 3.9e-46 157.5 0.9 1.8e-45 155.3 0.9 2.2 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KND97394.1 - 3.3e-13 49.8 3.6 3.3e-13 49.8 3.6 2.8 2 0 0 2 2 2 1 RasGEF N-terminal motif SLX9 PF15341.6 KND97395.1 - 7.8e-11 42.5 1.5 8.7e-11 42.3 1.5 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Forkhead PF00250.18 KND97396.1 - 4.1e-13 49.4 0.0 8.2e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KND97396.1 - 7.6e-10 39.0 0.1 1.5e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 FHA domain Lge1 PF11488.8 KND97396.1 - 0.039 14.2 0.1 0.039 14.2 0.1 3.1 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 RTX_C PF08339.10 KND97396.1 - 2.6 8.1 6.2 0.51 10.4 1.3 2.2 2 0 0 2 2 2 0 RTX C-terminal domain DUF3619 PF12279.8 KND97396.1 - 4.3 7.7 5.5 1.4 9.3 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3619) Proteasome PF00227.26 KND97397.1 - 2.7e-47 160.7 0.1 3.3e-47 160.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Ribosomal_L5_C PF00673.21 KND97398.1 - 1.3e-20 73.3 0.0 2e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KND97398.1 - 1.5e-19 70.0 0.1 5.3e-19 68.3 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 KND97398.1 - 0.0016 18.2 0.3 0.0035 17.0 0.3 1.5 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain BCAS2 PF05700.11 KND97399.1 - 6.7e-13 48.8 1.9 8e-13 48.6 1.9 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Beta_lactamase3 PF17030.5 KND97399.1 - 0.058 12.6 0.3 0.09 12.0 0.3 1.2 1 0 0 1 1 1 0 Putative beta-lactamase-like family PBP1_TM PF14812.6 KND97399.1 - 0.11 12.8 5.3 0.099 13.0 1.3 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FXR_C1 PF16096.5 KND97401.1 - 0.027 14.7 1.8 0.03 14.5 0.1 2.0 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Cofilin_ADF PF00241.20 KND97402.1 - 8.4e-27 93.4 0.0 5.1e-12 45.7 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein STD1 PF17235.2 KND97403.1 - 1.6e-26 93.2 0.3 1.6e-26 93.2 0.3 1.4 2 0 0 2 2 2 1 STD1/MTH1 DUF498 PF04430.14 KND97404.1 - 1.7e-15 57.0 0.0 2.6e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Pil1 PF13805.6 KND97407.1 - 4.2e-127 423.1 0.2 5.1e-127 422.9 0.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.11 KND97407.1 - 0.028 13.9 1.7 0.045 13.2 1.7 1.2 1 0 0 1 1 1 0 FAM92 protein DEADboxA PF12343.8 KND97408.1 - 0.079 13.5 0.0 0.096 13.2 0.0 1.2 1 0 0 1 1 1 0 Cold shock protein DEAD box A Tmemb_170 PF10190.9 KND97410.1 - 1.7e-12 47.6 16.6 4.8e-12 46.2 16.6 1.6 1 1 0 1 1 1 1 Putative transmembrane protein 170 DUF2516 PF10724.9 KND97410.1 - 0.098 12.9 10.3 0.15 12.4 10.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2516) Herpes_US9 PF06072.11 KND97410.1 - 0.32 10.9 4.0 0.12 12.3 0.9 2.0 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Peptidase_C48 PF02902.19 KND97412.1 - 1.6e-12 47.7 1.2 4.6e-12 46.2 1.2 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C5 PF00770.18 KND97412.1 - 0.0013 18.4 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 Adenovirus endoprotease c-SKI_SMAD_bind PF08782.10 KND97412.1 - 0.083 13.1 0.2 0.21 11.8 0.1 1.7 2 0 0 2 2 2 0 c-SKI Smad4 binding domain Peptidase_M24 PF00557.24 KND97413.1 - 2.8e-49 167.7 0.0 3.9e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KND97413.1 - 9.3e-36 122.3 0.0 1.7e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain RE_LlaJI PF09563.10 KND97413.1 - 0.049 12.8 0.0 0.095 11.9 0.0 1.4 1 0 0 1 1 1 0 LlaJI restriction endonuclease Band_7 PF01145.25 KND97414.1 - 9.5e-23 81.1 6.8 2.1e-22 80.0 6.8 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KND97414.1 - 0.00046 19.4 2.7 0.00065 18.9 2.7 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial DUF3103 PF11301.8 KND97414.1 - 0.09 11.5 0.2 0.14 10.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) Atg14 PF10186.9 KND97414.1 - 0.15 11.1 1.6 0.22 10.6 1.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MFS_1 PF07690.16 KND97415.1 - 1e-46 159.5 52.1 5.6e-45 153.8 52.1 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND97415.1 - 3.6e-10 39.3 16.1 3.6e-10 39.3 16.1 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KND97415.1 - 0.012 13.9 18.8 0.0074 14.6 3.8 2.7 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Prenyltransf PF01255.19 KND97418.1 - 0.0055 16.3 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase DUF5099 PF17025.5 KND97418.1 - 0.043 14.2 0.0 0.058 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5099) Arf PF00025.21 KND97419.1 - 1.1e-80 269.2 0.1 1.2e-80 269.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KND97419.1 - 1.6e-14 54.1 0.0 2.1e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KND97419.1 - 3.5e-14 52.7 0.0 4.3e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KND97419.1 - 2.4e-13 50.0 0.0 2.6e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KND97419.1 - 1.3e-12 47.6 0.9 9e-09 34.9 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KND97419.1 - 1.5e-10 40.8 0.0 1.9e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KND97419.1 - 3.5e-06 27.1 0.0 5.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KND97419.1 - 0.0027 17.0 0.5 0.0066 15.8 0.5 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase Ufd2P_core PF10408.9 KND97420.1 - 4.2e-183 610.4 0.8 5.3e-183 610.0 0.8 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KND97420.1 - 1.1e-25 89.5 2.0 1.5e-25 89.1 0.6 2.1 2 0 0 2 2 2 1 U-box domain HypD PF01924.16 KND97425.1 - 0.088 11.9 0.5 0.093 11.8 0.5 1.0 1 0 0 1 1 1 0 Hydrogenase formation hypA family AA_permease PF00324.21 KND97427.1 - 2.8e-132 441.7 41.2 3.4e-132 441.5 41.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND97427.1 - 1.5e-36 126.2 42.7 1.8e-36 125.9 42.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 KND97427.1 - 0.058 12.2 0.1 0.12 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) DUF3591 PF12157.8 KND97428.1 - 1e-176 588.0 5.7 1.6e-176 587.3 5.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 KND97428.1 - 2.4e-07 30.5 2.4 7.9e-07 28.8 2.4 1.9 1 0 0 1 1 1 1 Zinc knuckle RNase_T PF00929.24 KND97430.1 - 3.4e-09 37.5 0.1 7.6e-09 36.3 0.1 1.6 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 KND97430.1 - 5.7e-05 23.2 0.0 0.0002 21.4 0.0 1.9 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like Lipase_3 PF01764.25 KND97430.1 - 0.093 12.6 0.0 0.57 10.0 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 3) RNase_T PF00929.24 KND97431.1 - 4.4e-10 40.4 0.4 1.5e-08 35.4 0.1 2.5 2 0 0 2 2 2 1 Exonuclease DUF5051 PF16473.5 KND97431.1 - 0.00016 21.7 0.0 0.00032 20.7 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like DNA_pol_A_exo1 PF01612.20 KND97431.1 - 0.0043 16.8 0.5 0.034 13.9 0.5 2.2 1 1 0 1 1 1 1 3'-5' exonuclease Pox_C4_C10 PF03336.13 KND97434.1 - 0.023 13.8 0.1 0.024 13.8 0.1 1.0 1 0 0 1 1 1 0 Poxvirus C4/C10 protein Mo-co_dimer PF03404.16 KND97434.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain DUF5568 PF17724.1 KND97435.1 - 0.047 13.5 4.3 0.064 13.1 3.8 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5568) Lipoprotein_20 PF13942.6 KND97435.1 - 0.34 10.8 3.6 0.25 11.2 0.3 2.1 2 0 0 2 2 2 0 YfhG lipoprotein DUF382 PF04037.13 KND97435.1 - 0.66 10.1 0.0 0.66 10.1 0.0 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF382) GTP_EFTU PF00009.27 KND97437.1 - 3.7e-53 180.0 0.0 7.3e-53 179.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KND97437.1 - 7.2e-15 54.8 0.2 2.7e-14 53.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 KND97437.1 - 1.5e-12 47.4 0.0 4.2e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KND97437.1 - 1e-06 29.1 0.1 2.8e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 KND97437.1 - 0.00035 20.3 0.3 0.0021 17.8 0.0 2.5 3 1 0 3 3 3 1 Elongation factor G, domain IV RelB_N PF18506.1 KND97437.1 - 0.057 13.2 0.3 10 6.0 0.0 3.0 3 0 0 3 3 3 0 RelB Antitoxin alpha helical domain DUF3086 PF11285.8 KND97437.1 - 0.069 12.2 0.0 4.7 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) DEAD PF00270.29 KND97439.1 - 9.3e-43 146.0 0.0 1.3e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND97439.1 - 2.7e-28 98.5 0.1 5.4e-27 94.3 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND97439.1 - 0.0079 16.2 0.0 0.018 15.0 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit GATase_6 PF13522.6 KND97441.1 - 7.4e-13 48.9 0.0 1.6e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KND97441.1 - 3.8e-10 39.8 0.0 6.2e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KND97441.1 - 6.6e-08 32.2 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KND97441.1 - 7.5e-05 21.8 0.0 0.00015 20.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II NAC PF01849.18 KND97442.1 - 1.6e-17 63.2 0.2 3e-17 62.3 0.2 1.5 1 0 0 1 1 1 1 NAC domain MFS_1 PF07690.16 KND97443.1 - 6.3e-16 58.2 54.1 5.7e-14 51.8 33.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KND97443.1 - 1e-05 25.2 10.7 1e-05 25.2 10.7 2.1 2 0 0 2 2 2 1 Nodulin-like DEAD PF00270.29 KND97444.1 - 6.3e-46 156.3 0.4 2.7e-45 154.3 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND97444.1 - 4.3e-28 97.9 2.7 1.1e-27 96.5 0.4 2.6 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND97444.1 - 0.0002 21.4 2.4 0.0095 16.0 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KND97444.1 - 0.02 14.2 0.4 0.049 13.0 0.0 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Torus PF16131.5 KND97445.1 - 3.3e-33 114.6 0.0 9.2e-33 113.2 0.0 1.8 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 KND97445.1 - 6.7e-09 35.5 0.0 1.5e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAPA-1 PF04795.12 KND97445.1 - 0.039 14.8 8.9 1.6 9.6 6.6 2.3 2 0 0 2 2 2 0 PAPA-1-like conserved region EloA-BP1 PF15870.5 KND97445.1 - 0.07 13.4 1.7 0.11 12.7 1.7 1.4 1 0 0 1 1 1 0 ElonginA binding-protein 1 zf-CCCH_4 PF18044.1 KND97445.1 - 0.082 12.7 6.5 0.13 12.1 6.5 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger AKAP7_RIRII_bdg PF10470.9 KND97445.1 - 0.18 11.9 5.8 0.34 11.0 1.9 2.4 2 0 0 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein zf-CCCH_2 PF14608.6 KND97445.1 - 0.46 11.0 5.4 0.98 10.0 5.4 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DUF4407 PF14362.6 KND97445.1 - 0.59 9.4 3.4 1.1 8.5 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf_CCCH_4 PF18345.1 KND97445.1 - 1.1 9.4 7.3 1.9 8.6 7.3 1.4 1 0 0 1 1 1 0 Zinc finger domain DUF1923 PF09083.10 KND97448.1 - 0.07 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1923) MFS_1 PF07690.16 KND97455.1 - 3.4e-32 111.7 27.2 3.4e-32 111.7 27.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MMPL PF03176.15 KND97455.1 - 0.68 8.8 2.6 0.5 9.3 0.2 1.9 2 0 0 2 2 2 0 MMPL family Nitro_FeMo-Co PF02579.17 KND97456.1 - 0.052 13.9 0.1 0.058 13.7 0.1 1.1 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor Catalase PF00199.19 KND97458.1 - 7e-74 249.2 0.1 1.1e-73 248.5 0.1 1.3 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KND97458.1 - 1.8e-12 47.3 0.4 2.5e-11 43.6 0.1 2.4 2 0 0 2 2 2 1 Catalase-related immune-responsive RAI1 PF08652.11 KND97460.1 - 1.7e-25 89.0 0.3 4.5e-25 87.6 0.0 1.9 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease Med29 PF11568.8 KND97460.1 - 0.13 12.4 0.6 5.2 7.3 0.0 2.4 1 1 1 2 2 2 0 Mediator complex subunit 29 Sad1_UNC PF07738.13 KND97461.1 - 6.8e-30 103.8 0.1 1.5e-29 102.6 0.1 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal KRAP_IP3R_bind PF14722.6 KND97461.1 - 0.035 13.9 0.0 0.035 13.9 0.0 2.6 3 0 0 3 3 3 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain DUF773 PF05600.12 KND97461.1 - 0.18 10.5 6.2 0.28 9.9 6.2 1.2 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 DEAD PF00270.29 KND97462.1 - 4.1e-31 108.1 0.0 8e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND97462.1 - 2.7e-20 72.8 0.1 9.7e-20 71.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND97462.1 - 2e-05 24.6 0.0 3.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Mso1_Sec1_bdg PF14475.6 KND97463.1 - 1.1e-17 63.3 0.0 1.8e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 NAT PF04768.13 KND97465.1 - 1.1e-52 178.1 0.0 3.4e-52 176.5 0.0 1.8 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 KND97465.1 - 6.8e-30 104.0 0.0 1.5e-29 102.8 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 KND97465.1 - 1.5e-26 93.5 0.0 3.4e-26 92.3 0.0 1.6 2 0 0 2 2 2 1 Amino acid kinase family Semialdhyde_dhC PF02774.18 KND97465.1 - 4.3e-07 30.2 0.1 1.6e-06 28.3 0.1 1.9 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.20 KND97465.1 - 0.0022 18.1 0.0 0.0085 16.2 0.0 2.1 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Ferlin_C PF16165.5 KND97471.1 - 0.23 11.4 5.0 0.32 10.9 5.0 1.2 1 0 0 1 1 1 0 Ferlin C-terminus FMP23 PF17315.2 KND97472.1 - 1.4e-12 48.0 13.7 0.0095 16.1 0.2 6.0 4 2 1 5 5 5 5 Found in mitochondrial proteome Tma16 PF11176.8 KND97473.1 - 2.4e-38 131.3 8.3 2.7e-38 131.1 8.3 1.0 1 0 0 1 1 1 1 Translation machinery-associated protein 16 OmpH PF03938.14 KND97473.1 - 1.1 9.6 5.9 0.19 12.0 2.5 1.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Peptidase_S49_N PF08496.10 KND97473.1 - 4.1 7.4 7.5 6.3 6.8 5.0 1.9 1 1 1 2 2 2 0 Peptidase family S49 N-terminal CAF20 PF17052.5 KND97475.1 - 9.1e-56 188.4 2.5 1e-55 188.2 2.5 1.0 1 0 0 1 1 1 1 Cap associated factor RRP7 PF12923.7 KND97475.1 - 0.002 18.3 2.7 0.0038 17.4 0.6 2.0 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain FAM180 PF15173.6 KND97476.1 - 0.1 12.6 2.1 0.17 11.9 0.8 2.0 2 0 0 2 2 2 0 FAM180 family YqzE PF14038.6 KND97482.1 - 0.28 11.2 3.1 0.4 10.7 3.1 1.3 1 0 0 1 1 1 0 YqzE-like protein PTS_2-RNA PF01885.16 KND97483.1 - 3.8e-56 190.0 0.0 4.3e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Complex1_LYR PF05347.15 KND97484.1 - 6.5e-07 29.3 0.4 1.1e-06 28.6 0.4 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KND97484.1 - 0.0045 17.7 0.8 0.0061 17.3 0.8 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Cystatin PF00031.21 KND97484.1 - 0.03 14.6 0.4 0.05 13.9 0.4 1.5 1 0 0 1 1 1 0 Cystatin domain Utp8 PF10395.9 KND97485.1 - 2.7e-142 475.7 20.4 3.1e-142 475.5 20.4 1.0 1 0 0 1 1 1 1 Utp8 family VPS11_C PF12451.8 KND97486.1 - 2.5e-13 50.0 0.6 8.2e-13 48.4 0.1 2.3 2 0 0 2 2 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 KND97486.1 - 8.7e-08 32.1 2.5 8.7e-08 32.1 2.5 2.0 2 0 0 2 2 2 1 Zinc-finger Clathrin PF00637.20 KND97486.1 - 0.0011 18.9 4.9 0.011 15.6 4.8 2.9 1 1 0 1 1 1 1 Region in Clathrin and VPS zf-RING_5 PF14634.6 KND97486.1 - 0.0011 18.9 4.6 0.0025 17.8 4.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KND97486.1 - 0.0045 17.2 1.9 0.011 16.0 1.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain PPR PF01535.20 KND97486.1 - 0.02 15.1 0.3 0.1 12.9 0.1 2.4 2 0 0 2 2 2 0 PPR repeat zf-C3HC4_2 PF13923.6 KND97486.1 - 0.029 14.2 7.4 0.16 11.9 7.5 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.6 KND97486.1 - 0.069 12.8 0.5 0.2 11.4 0.2 2.0 2 0 0 2 2 2 0 TPR repeat zf-RING_UBOX PF13445.6 KND97486.1 - 0.079 13.0 3.5 0.11 12.5 2.3 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 KND97486.1 - 0.08 13.0 0.2 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KND97486.1 - 0.23 11.2 2.2 0.41 10.4 0.6 2.3 2 0 0 2 2 2 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 KND97486.1 - 0.27 10.9 5.4 0.06 13.0 0.4 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 KND97486.1 - 0.37 11.1 9.1 0.039 14.3 3.8 2.2 2 0 0 2 2 2 0 Ring finger domain zf-MIZ PF02891.20 KND97486.1 - 0.45 10.3 2.0 0.96 9.2 2.0 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger TPR_2 PF07719.17 KND97486.1 - 0.73 10.1 3.5 1.6 9.0 0.2 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-Nse PF11789.8 KND97486.1 - 0.98 9.3 4.6 1.1 9.2 2.6 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.25 KND97486.1 - 3 7.8 12.7 0.054 13.4 5.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Reticulon PF02453.17 KND97488.1 - 5.8e-32 110.8 3.3 8.3e-32 110.3 3.3 1.2 1 0 0 1 1 1 1 Reticulon ESR1_C PF12743.7 KND97488.1 - 0.034 13.9 0.3 0.21 11.4 0.5 2.2 2 0 0 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal Methyltransf_4 PF02390.17 KND97489.1 - 4.6e-60 202.0 0.2 4.6e-60 202.0 0.2 1.5 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KND97489.1 - 2.7e-05 23.8 0.0 0.00022 20.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KND97489.1 - 0.00081 20.1 0.0 0.0032 18.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND97489.1 - 0.0036 17.1 1.1 0.0055 16.5 0.1 1.9 2 1 0 2 2 2 1 Methyltransferase domain CREPT PF16566.5 KND97489.1 - 0.0047 17.1 6.6 0.2 11.8 3.3 2.4 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour Methyltransf_12 PF08242.12 KND97489.1 - 0.0049 17.6 0.3 0.025 15.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain KLRAQ PF10205.9 KND97489.1 - 0.017 15.3 4.1 0.06 13.6 4.1 1.9 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein CMAS PF02353.20 KND97489.1 - 0.019 14.3 0.0 0.039 13.2 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 KND97489.1 - 0.042 13.8 1.3 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain PDGLE PF13190.6 KND97489.1 - 0.091 12.7 0.2 0.25 11.3 0.2 1.8 1 1 0 1 1 1 0 PDGLE domain DUF4739 PF15893.5 KND97489.1 - 0.094 12.3 2.9 0.17 11.4 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4739) MetW PF07021.12 KND97489.1 - 0.095 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DOT1 PF08123.13 KND97489.1 - 0.12 11.9 0.5 0.46 10.0 0.0 2.1 2 1 1 3 3 3 0 Histone methylation protein DOT1 CTNNB1_binding PF08347.11 KND97489.1 - 0.96 9.6 5.8 1.5 9.0 5.8 1.6 1 1 0 1 1 1 0 N-terminal CTNNB1 binding ATP-synt_E PF05680.12 KND97489.1 - 7.4 7.0 11.5 2.2 8.7 7.0 2.2 2 0 0 2 2 2 0 ATP synthase E chain Ribosomal_L10 PF00466.20 KND97490.1 - 3.5e-05 23.9 0.1 6.3e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribonuclease_3 PF00636.26 KND97491.1 - 2.4e-22 79.5 0.1 1e-21 77.5 0.0 2.1 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KND97491.1 - 1.5e-21 76.9 0.4 1.1e-20 74.1 0.1 2.3 2 0 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.26 KND97491.1 - 2.5e-12 47.3 0.3 4.4e-05 24.1 0.3 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif RNase_3_N PF18497.1 KND97491.1 - 0.00031 20.9 0.1 0.00075 19.7 0.1 1.6 1 0 0 1 1 1 1 Ribonuclease III N-terminal domain DAAD PF18752.1 KND97491.1 - 0.032 14.1 0.3 0.065 13.1 0.3 1.5 1 0 0 1 1 1 0 Dictyosteliid AID/APOBEC-like Deaminase TQ PF18202.1 KND97491.1 - 0.19 12.3 1.9 0.31 11.5 0.6 2.1 2 0 0 2 2 2 0 T-Q ester bond containing domain Peptidase_M24 PF00557.24 KND97494.1 - 6.1e-06 26.1 0.0 1.8e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Metallopeptidase family M24 14-3-3 PF00244.20 KND97495.1 - 1.9e-103 344.8 4.7 2.2e-103 344.5 4.7 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 KND97495.1 - 0.00012 22.1 0.3 0.00028 20.9 0.3 1.6 1 0 0 1 1 1 1 Flagellar protein FlaF CDH-cyt PF16010.5 KND97495.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Cytochrome domain of cellobiose dehydrogenase Septin PF00735.18 KND97496.1 - 3e-114 381.1 0.1 4.3e-114 380.5 0.1 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KND97496.1 - 5.3e-07 29.7 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KND97496.1 - 1.9e-05 24.6 5.4 0.0009 19.2 0.4 3.5 3 1 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 KND97496.1 - 5.5e-05 22.8 0.3 0.0055 16.3 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KND97496.1 - 0.0012 19.3 0.2 0.0034 17.8 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KND97496.1 - 0.0058 16.9 0.0 0.017 15.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AIG1 PF04548.16 KND97496.1 - 0.0087 15.4 0.1 0.021 14.2 0.1 1.6 1 0 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.18 KND97496.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Myosin_head PF00063.21 KND97496.1 - 0.011 14.0 0.0 0.019 13.2 0.0 1.3 1 0 0 1 1 1 0 Myosin head (motor domain) AAA_24 PF13479.6 KND97496.1 - 0.018 14.8 0.1 0.038 13.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 KND97496.1 - 0.023 14.9 0.2 0.059 13.6 0.0 1.8 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KND97496.1 - 0.025 14.5 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF5082 PF16888.5 KND97496.1 - 0.032 14.5 0.9 0.059 13.7 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Pox_A32 PF04665.12 KND97496.1 - 0.034 13.6 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein DUF29 PF01724.16 KND97496.1 - 0.034 14.4 1.2 0.91 9.8 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF29 KAP_NTPase PF07693.14 KND97496.1 - 0.039 13.2 0.0 0.063 12.5 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain RNA_helicase PF00910.22 KND97496.1 - 0.064 13.7 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 KND97496.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain XhlA PF10779.9 KND97496.1 - 0.11 12.7 0.6 0.33 11.2 0.6 1.8 1 0 0 1 1 1 0 Haemolysin XhlA Zn_clus PF00172.18 KND97497.1 - 2.1e-07 31.0 11.0 3.3e-07 30.3 11.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homeodomain PF00046.29 KND97500.1 - 0.00046 20.0 1.1 0.00084 19.1 1.1 1.5 1 0 0 1 1 1 1 Homeodomain YjbE PF11106.8 KND97501.1 - 0.0019 18.4 0.7 0.0036 17.5 0.7 1.4 1 0 0 1 1 1 1 Exopolysaccharide production protein YjbE WD40 PF00400.32 KND97502.1 - 5.1e-22 77.8 0.5 0.00012 22.8 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND97502.1 - 2.4e-11 43.7 0.0 0.00073 19.8 0.0 4.5 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KND97502.1 - 0.0038 16.8 0.1 0.0065 16.1 0.1 1.3 1 0 0 1 1 1 1 PQQ-like domain DUF4050 PF13259.6 KND97502.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) DLH PF01738.18 KND97503.1 - 1.7e-27 96.4 0.0 2.1e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family LIDHydrolase PF10230.9 KND97503.1 - 0.057 13.0 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase 4F5 PF04419.14 KND97504.1 - 3.8e-08 34.0 20.0 8.7e-08 32.9 20.0 1.7 1 1 0 1 1 1 1 4F5 protein family Caldesmon PF02029.15 KND97504.1 - 0.1 11.3 12.4 0.11 11.2 12.4 1.0 1 0 0 1 1 1 0 Caldesmon ArsA_ATPase PF02374.15 KND97506.1 - 7.9e-107 357.0 0.2 9.2e-107 356.7 0.2 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KND97506.1 - 1.2e-08 35.0 0.6 3.5e-08 33.6 0.1 1.9 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 KND97506.1 - 2e-07 31.1 0.2 5.5e-07 29.7 0.2 2.0 1 1 1 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KND97506.1 - 0.00019 21.0 4.4 0.013 14.9 1.6 2.8 2 1 1 3 3 3 2 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 KND97506.1 - 0.005 16.3 0.0 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NB-ARC PF00931.22 KND97506.1 - 0.0081 15.4 0.0 0.02 14.1 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain ATPase PF06745.13 KND97506.1 - 0.0092 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 KaiC Zeta_toxin PF06414.12 KND97506.1 - 0.034 13.4 0.0 0.067 12.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.22 KND97506.1 - 0.13 11.9 0.0 0.36 10.4 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF3112 PF11309.8 KND97508.1 - 3.9e-91 304.3 6.7 6.9e-91 303.5 6.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3112) DUF3112 PF11309.8 KND97509.1 - 2.5e-85 285.4 8.8 4.5e-85 284.5 8.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3112) TMEM132D_C PF15706.5 KND97509.1 - 0.1 12.4 3.1 5.7 6.8 0.7 2.5 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF3754 PF12576.8 KND97509.1 - 0.21 11.5 3.1 0.74 9.8 3.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3754) DUF4029 PF13221.6 KND97509.1 - 0.99 10.1 9.3 0.73 10.5 1.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4029) DUF3112 PF11309.8 KND97510.1 - 8.3e-98 326.2 4.8 1.3e-97 325.5 4.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3112) Cortexin PF11057.8 KND97510.1 - 5.3 7.0 7.4 0.57 10.1 0.2 2.8 3 0 0 3 3 3 0 Cortexin of kidney Ctf8 PF09696.10 KND97511.1 - 3e-26 92.4 0.2 7.2e-26 91.2 0.2 1.6 1 1 0 1 1 1 1 Ctf8 Y_phosphatase3 PF13350.6 KND97512.1 - 5.1e-59 200.1 0.0 7.4e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Abhydrolase_1 PF00561.20 KND97512.1 - 9.7e-08 32.0 0.4 7.8e-05 22.4 0.2 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KND97512.1 - 1e-06 28.2 0.1 9.1e-05 21.8 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KND97512.1 - 6.2e-06 25.8 0.1 5e-05 22.9 0.1 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Y_phosphatase PF00102.27 KND97512.1 - 0.0051 16.4 0.0 0.0096 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KND97512.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF2202 PF09968.9 KND97512.1 - 0.12 12.2 0.2 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein domain (DUF2202) EAP30 PF04157.16 KND97514.1 - 1e-47 162.4 0.0 1.2e-47 162.2 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Sec7_N PF12783.7 KND97514.1 - 0.063 13.2 0.1 2.8 7.8 0.1 2.2 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal PseudoU_synth_1 PF01416.20 KND97515.1 - 1.3e-33 115.6 0.0 1.7e-32 112.1 0.0 2.3 2 0 0 2 2 2 1 tRNA pseudouridine synthase DEAD PF00270.29 KND97516.1 - 6.5e-42 143.3 0.1 1.1e-41 142.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND97516.1 - 6.3e-21 74.8 0.0 2.1e-20 73.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KND97516.1 - 5.2e-18 65.0 0.6 1.2e-17 63.9 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KND97516.1 - 2.2e-05 24.6 3.2 0.00019 21.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Pet20 PF08692.10 KND97516.1 - 0.03 15.0 1.2 0.07 13.8 1.2 1.6 1 0 0 1 1 1 0 Mitochondrial protein Pet20 AAA_22 PF13401.6 KND97516.1 - 0.18 12.1 0.5 2 8.7 0.5 2.6 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 KND97516.1 - 0.35 10.2 0.0 0.35 10.2 0.0 2.7 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit SpoIIIAH PF12685.7 KND97516.1 - 1.1 9.0 11.0 2 8.2 11.0 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Transformer PF06495.11 KND97516.1 - 3.9 7.5 6.8 7 6.7 6.8 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein U79_P34 PF03064.16 KND97516.1 - 7 5.9 15.4 14 5.0 15.4 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 ThiF PF00899.21 KND97517.1 - 3.3e-21 75.7 0.0 5.2e-21 75.1 0.0 1.3 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 KND97517.1 - 0.0069 16.6 0.6 2.1 8.6 0.0 3.4 3 0 0 3 3 3 1 Ubiquitin-activating enzyme E1 four-helix bundle VWA_N PF08399.11 KND97517.1 - 0.098 13.1 0.3 0.22 12.0 0.0 1.7 2 0 0 2 2 2 0 VWA N-terminal SPX PF03105.19 KND97518.1 - 1.1e-41 144.0 8.5 1.9e-41 143.2 8.5 1.4 1 0 0 1 1 1 1 SPX domain zf-RING_2 PF13639.6 KND97518.1 - 5.4e-07 29.8 8.6 1e-06 29.0 8.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KND97518.1 - 1.1e-06 28.4 7.8 2.4e-06 27.3 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KND97518.1 - 1.5e-06 28.0 7.2 2.6e-06 27.2 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KND97518.1 - 1.8e-06 27.7 9.1 3.4e-06 26.8 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KND97518.1 - 3.2e-06 27.2 7.7 3.2e-06 27.2 7.7 1.7 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KND97518.1 - 4.4e-05 23.4 7.0 9.5e-05 22.3 7.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KND97518.1 - 0.00081 19.2 9.8 0.015 15.1 10.2 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KND97518.1 - 0.00093 19.1 10.5 0.0053 16.7 10.8 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 KND97518.1 - 0.0017 18.1 2.4 0.0017 18.1 2.4 1.9 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KND97518.1 - 0.043 13.9 3.1 0.085 12.9 3.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 KND97518.1 - 0.1 12.7 3.7 0.64 10.2 4.1 2.0 2 0 0 2 2 2 0 zinc RING finger of MSL2 Thump_like PF18096.1 KND97518.1 - 0.18 11.7 2.1 15 5.6 0.1 3.5 3 0 0 3 3 3 0 THUMP domain-like zf-rbx1 PF12678.7 KND97518.1 - 0.23 11.8 7.9 0.67 10.3 7.9 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain TerY_C PF15616.6 KND97518.1 - 0.3 11.2 3.9 0.64 10.1 3.3 1.8 1 1 0 1 1 1 0 TerY-C metal binding domain Zn-ribbon_8 PF09723.10 KND97518.1 - 0.99 9.6 3.7 1.1 9.5 1.3 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Pyr_redox_2 PF07992.14 KND97519.1 - 2.7e-43 148.3 0.0 3.4e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KND97519.1 - 6.7e-09 36.2 0.0 4e-08 33.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF1358 PF07096.11 KND97519.1 - 0.0098 15.9 1.1 0.048 13.6 0.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1358) Pyr_redox_3 PF13738.6 KND97519.1 - 0.058 12.6 0.2 3.1 7.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase EF-hand_9 PF14658.6 KND97519.1 - 0.17 12.2 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain Mod_r PF07200.13 KND97520.1 - 3.7e-10 40.1 2.6 4.9e-10 39.7 2.6 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Ank_4 PF13637.6 KND97521.1 - 7.3e-09 36.0 0.4 0.0019 18.7 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KND97521.1 - 1.5e-08 35.1 1.9 0.0033 18.0 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) KilA-N PF04383.13 KND97521.1 - 4.1e-07 29.8 0.1 4.9e-06 26.4 0.1 2.6 1 1 0 1 1 1 1 KilA-N domain Ank_3 PF13606.6 KND97521.1 - 1.8e-06 27.8 0.3 0.027 15.0 0.1 4.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KND97521.1 - 2.6e-06 27.6 0.4 0.058 13.7 0.1 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KND97521.1 - 3.4e-05 24.1 0.2 1.2 9.8 0.1 4.4 4 0 0 4 4 4 1 Ankyrin repeat zinc_ribbon_10 PF10058.9 KND97523.1 - 1.6e-19 69.3 0.3 2.6e-19 68.7 0.3 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein ALIX_LYPXL_bnd PF13949.6 KND97523.1 - 0.046 13.0 1.7 0.07 12.4 0.3 1.8 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV DivIC PF04977.15 KND97523.1 - 0.1 12.4 0.2 16 5.4 0.2 2.9 3 0 0 3 3 3 0 Septum formation initiator NAC PF01849.18 KND97524.1 - 3.5e-16 58.9 1.2 3.5e-16 58.9 1.2 2.5 3 0 0 3 3 3 1 NAC domain PhoLip_ATPase_C PF16212.5 KND97525.1 - 4.6e-73 246.0 29.4 4.6e-73 246.0 29.4 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KND97525.1 - 3.6e-17 61.8 0.1 1.7e-16 59.7 0.1 2.1 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KND97525.1 - 2.9e-10 40.1 0.0 6.8e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KND97525.1 - 1.9e-09 38.1 0.4 0.0028 18.0 0.0 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KND97525.1 - 5.8e-07 29.2 0.3 1.6e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KND97525.1 - 0.00034 20.4 0.3 0.0011 18.8 0.3 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Lactamase_B_6 PF16661.5 KND97526.1 - 4.5e-54 182.8 0.0 7.1e-54 182.2 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KND97526.1 - 3e-19 69.9 13.3 3.3e-18 66.4 0.1 4.0 3 1 1 4 4 4 2 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KND97526.1 - 9e-12 45.3 0.0 2.4e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 KND97526.1 - 7.2e-06 25.8 0.0 2e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Ndufs5 PF10200.9 KND97527.1 - 5.8e-05 23.3 0.2 6.7e-05 23.1 0.2 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CHCH PF06747.13 KND97527.1 - 0.019 15.1 2.3 0.047 13.8 2.2 1.7 1 1 0 1 1 1 0 CHCH domain DUF3128 PF11326.8 KND97527.1 - 0.057 13.8 3.7 1.9 8.9 3.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) COX6B PF02297.17 KND97527.1 - 0.062 13.5 6.3 0.38 11.0 6.3 2.0 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb NOC3p PF07540.11 KND97528.1 - 3.5e-21 75.5 0.4 1.3e-20 73.6 0.4 2.1 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 KND97528.1 - 7.2e-15 55.4 1.3 7.2e-15 55.4 1.3 2.0 2 0 0 2 2 2 1 CBF/Mak21 family Lipoprotein_2 PF00921.17 KND97528.1 - 2.1 7.8 4.9 0.33 10.5 0.3 1.8 2 0 0 2 2 2 0 Borrelia lipoprotein PAP_central PF04928.17 KND97528.1 - 8.2 5.3 6.1 1.5 7.7 0.1 2.4 3 0 0 3 3 3 0 Poly(A) polymerase central domain p450 PF00067.22 KND97529.1 - 4.1e-48 164.3 0.0 7.2e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 SinI PF08671.10 KND97529.1 - 0.074 12.8 0.3 0.17 11.7 0.3 1.6 1 0 0 1 1 1 0 Anti-repressor SinI 6PGD PF00393.19 KND97530.1 - 5.2e-127 423.2 0.0 6.9e-127 422.8 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KND97530.1 - 1.6e-51 174.6 0.0 2.4e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KND97530.1 - 0.0057 17.2 0.1 0.011 16.2 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KND97530.1 - 0.013 15.6 0.2 0.1 12.7 0.1 2.2 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KND97530.1 - 0.023 14.1 0.0 0.052 12.9 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_11 PF14833.6 KND97530.1 - 0.053 13.8 0.0 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Attachment_P66 PF11263.8 KND97531.1 - 0.023 13.9 0.0 0.023 13.9 0.0 1.0 1 0 0 1 1 1 0 Borrelia burgdorferi attachment protein P66 ATP-sulfurylase PF01747.17 KND97532.1 - 4.2e-81 271.5 0.0 5.6e-81 271.1 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 KND97532.1 - 3.1e-48 163.4 0.0 5e-48 162.8 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain CTP_transf_like PF01467.26 KND97532.1 - 0.014 15.6 0.0 0.041 14.1 0.0 1.8 2 0 0 2 2 2 0 Cytidylyltransferase-like Acid_PPase PF12689.7 KND97534.1 - 3.9e-45 153.7 0.0 4.3e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_SAK_2 PF18143.1 KND97534.1 - 0.047 14.0 0.0 0.057 13.7 0.0 1.1 1 0 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins ZZ PF00569.17 KND97535.1 - 3.5 7.5 10.7 14 5.6 10.7 1.9 1 1 0 1 1 1 0 Zinc finger, ZZ type DRIM PF07539.12 KND97537.1 - 1.3e-79 268.2 12.7 1.3e-79 268.2 12.7 3.4 3 0 0 3 3 3 1 Down-regulated in metastasis Suppressor_P21 PF11479.8 KND97537.1 - 0.1 12.8 0.9 27 5.0 0.0 4.3 3 0 0 3 3 3 0 RNA silencing suppressor P21 C-terminal domain DUF155 PF02582.14 KND97538.1 - 2.7e-53 180.7 1.3 4.5e-53 179.9 1.3 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 KND97538.1 - 0.02 15.4 0.1 0.052 14.0 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 AIM24 PF01987.17 KND97542.1 - 9.2e-21 74.6 0.0 1.2e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 PIP5K PF01504.18 KND97543.1 - 1.7e-95 319.4 1.0 3.2e-95 318.5 0.5 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF5611 PF18446.1 KND97543.1 - 0.11 13.3 0.7 3.9 8.4 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5611) DUF1157 PF06636.11 KND97544.1 - 0.023 13.6 0.1 0.032 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1157) MAF_flag10 PF01973.18 KND97544.1 - 0.03 14.0 0.1 0.14 11.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF115 Suc_Fer-like PF06999.12 KND97545.1 - 5.2e-50 170.0 0.0 6.2e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Thioredoxin PF00085.20 KND97546.1 - 4.9e-08 32.9 0.0 1.7e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin ERp29_N PF07912.13 KND97546.1 - 0.087 13.0 0.1 0.32 11.1 0.0 1.9 2 0 0 2 2 2 0 ERp29, N-terminal domain DUF836 PF05768.14 KND97547.1 - 2.2e-14 53.6 0.9 2.9e-14 53.2 0.9 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KND97547.1 - 0.0069 16.6 0.3 0.013 15.8 0.3 1.5 1 0 0 1 1 1 1 Glutaredoxin adh_short PF00106.25 KND97548.1 - 3.9e-45 153.7 0.0 5.1e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND97548.1 - 9.5e-28 97.3 0.0 1.2e-27 97.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND97548.1 - 2e-07 31.1 0.0 3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KND97548.1 - 7.5e-07 28.8 0.0 5.6e-06 25.9 0.0 2.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KND97548.1 - 0.00045 20.2 0.0 0.00071 19.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KND97548.1 - 0.00083 18.9 0.0 0.0019 17.7 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KND97548.1 - 0.048 12.8 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DNA_pol_lambd_f PF10391.9 KND97548.1 - 0.065 13.1 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda NmrA PF05368.13 KND97548.1 - 0.066 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DUF676 PF05057.14 KND97549.1 - 1.2e-40 139.4 0.0 1.9e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 KND97549.1 - 0.013 14.7 0.2 0.024 13.8 0.2 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Transket_pyr PF02779.24 KND97550.1 - 1.5e-64 216.9 0.0 3.5e-64 215.7 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KND97550.1 - 1.4e-56 191.7 0.0 2e-56 191.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KND97550.1 - 7.3e-52 175.1 0.0 1.1e-51 174.5 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KND97550.1 - 6.5e-19 67.3 1.3 6.5e-19 67.3 1.3 1.8 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus Pam17 PF08566.10 KND97551.1 - 4.5e-58 195.7 0.0 5.5e-58 195.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 BPD_transp_2 PF02653.16 KND97551.1 - 0.001 18.3 0.2 0.0014 17.8 0.2 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component SNF2_N PF00176.23 KND97552.1 - 1.9e-71 240.6 1.3 4.5e-71 239.4 1.3 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KND97552.1 - 6.7e-23 81.2 0.0 2.5e-20 72.9 0.0 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 KND97552.1 - 2.9e-19 68.9 0.4 1.3e-18 66.8 0.4 2.2 1 0 0 1 1 1 1 Bromodomain ResIII PF04851.15 KND97552.1 - 1.5e-12 47.9 0.0 1.5e-12 47.9 0.0 3.6 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit SnAC PF14619.6 KND97552.1 - 1.3e-08 35.3 2.3 1.3e-08 35.3 2.3 4.3 4 1 1 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.13 KND97552.1 - 6.2e-05 23.2 7.1 6.2e-05 23.2 7.1 3.6 3 0 0 3 3 3 1 HSA Rop-like PF05082.13 KND97552.1 - 0.0044 16.8 1.1 2.6 7.9 0.0 3.1 2 0 0 2 2 2 2 Rop-like CheR_N PF03705.15 KND97552.1 - 0.025 14.3 1.2 3.1 7.6 0.0 4.2 5 0 0 5 5 5 0 CheR methyltransferase, all-alpha domain peroxidase PF00141.23 KND97553.1 - 2.6e-39 135.3 0.0 5.8e-39 134.1 0.0 1.6 2 0 0 2 2 2 1 Peroxidase Ribosomal_L6 PF00347.23 KND97554.1 - 5e-29 100.8 4.7 1.9e-16 60.5 0.7 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 PDT PF00800.18 KND97555.1 - 0.00013 21.9 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 KND97555.1 - 0.0009 19.0 0.0 0.0077 16.0 0.0 2.1 1 1 1 2 2 2 1 ACT domain zf-rbx1 PF12678.7 KND97556.1 - 1.1e-22 80.1 12.8 1.6e-22 79.5 12.8 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KND97556.1 - 1.3e-15 57.2 10.2 1.8e-15 56.8 10.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KND97556.1 - 9.6e-05 22.6 13.6 0.0031 17.8 13.6 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KND97556.1 - 0.00015 21.6 2.8 0.00015 21.6 2.8 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KND97556.1 - 0.011 15.5 1.6 0.011 15.5 1.6 2.4 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4 PF00097.25 KND97556.1 - 0.012 15.5 11.5 0.12 12.3 11.5 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KND97556.1 - 0.17 12.0 7.7 0.98 9.5 7.7 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KND97556.1 - 0.55 10.4 7.8 2.2 8.5 0.4 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-HC5HC2H PF13771.6 KND97556.1 - 1.5 9.1 9.9 71 3.7 9.9 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_5 PF14634.6 KND97556.1 - 6.3 6.8 10.4 36 4.4 10.4 2.1 1 1 0 1 1 1 0 zinc-RING finger domain Med7 PF05983.11 KND97557.1 - 6.4e-58 196.0 2.5 7.4e-58 195.8 2.5 1.0 1 0 0 1 1 1 1 MED7 protein Adaptin_N PF01602.20 KND97558.1 - 1.9e-116 389.7 11.7 2.7e-116 389.2 11.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KND97558.1 - 5e-59 199.0 1.3 5e-59 199.0 1.3 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KND97558.1 - 3.2e-09 37.0 0.4 1.4e-05 25.4 0.0 3.9 3 1 1 4 4 4 1 HEAT repeats HEAT PF02985.22 KND97558.1 - 7.3e-08 32.0 0.9 0.41 11.0 0.0 4.6 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.6 KND97558.1 - 0.0003 21.2 0.8 0.21 12.1 0.1 3.9 3 1 1 4 4 4 1 HEAT-like repeat Arm PF00514.23 KND97558.1 - 0.099 12.7 0.0 2 8.6 0.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Guanylate_kin PF00625.21 KND97558.1 - 0.11 12.2 0.1 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 Guanylate kinase Mog1 PF04603.12 KND97559.1 - 7e-31 107.4 0.0 2.6e-30 105.6 0.0 1.8 1 1 0 1 1 1 1 Ran-interacting Mog1 protein Gly_transf_sug PF04488.15 KND97561.1 - 1.8e-14 54.1 0.0 4.5e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Sacchrp_dh_C PF16653.5 KND97562.1 - 8.4e-95 317.8 0.0 1.2e-94 317.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KND97562.1 - 1.8e-25 89.7 0.4 2.7e-25 89.1 0.4 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KND97562.1 - 1e-07 32.1 0.1 2.3e-07 31.0 0.1 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KND97562.1 - 5.9e-06 26.3 0.5 1.2e-05 25.3 0.5 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KND97562.1 - 0.0079 16.6 0.2 0.019 15.4 0.2 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KND97562.1 - 0.0089 16.1 0.2 0.019 15.1 0.2 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 KND97562.1 - 0.02 15.7 0.5 0.083 13.7 0.2 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.18 KND97562.1 - 0.033 14.5 0.3 0.061 13.6 0.3 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_3 PF03447.16 KND97562.1 - 0.1 13.3 0.2 0.23 12.1 0.2 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain NmrA PF05368.13 KND97562.1 - 0.11 12.0 0.2 0.2 11.2 0.2 1.4 1 0 0 1 1 1 0 NmrA-like family Tubulin_3 PF14881.6 KND97563.1 - 5.8e-26 91.3 0.2 1.1e-25 90.4 0.2 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 KND97563.1 - 1.4e-11 44.7 0.2 2.5e-11 43.9 0.2 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 KND97563.1 - 0.0028 17.9 0.0 0.02 15.1 0.0 2.3 3 0 0 3 3 3 1 Tubulin/FtsZ family, GTPase domain DUF3134 PF11332.8 KND97563.1 - 2.4 8.5 4.9 0.95 9.8 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3134) LIP PF03583.14 KND97564.1 - 3.3e-88 295.7 0.0 4.4e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 KND97564.1 - 0.0013 18.3 0.0 0.45 9.9 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family DnaJ PF00226.31 KND97568.1 - 1.1e-24 86.3 1.7 1.7e-24 85.7 1.7 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 KND97568.1 - 2e-21 76.7 0.0 2.6e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KND97568.1 - 1.7e-14 53.9 22.2 3.3e-14 53.0 22.2 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KND97568.1 - 0.00012 22.0 7.1 0.067 13.2 0.6 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein RPT PF13446.6 KND97568.1 - 0.058 13.3 0.0 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 A repeated domain in UCH-protein HypA PF01155.19 KND97568.1 - 0.86 9.6 13.0 3.3 7.8 2.2 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PIG-X PF08320.12 KND97569.1 - 6e-40 137.4 0.0 9.1e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 DUF2526 PF10735.9 KND97569.1 - 0.1 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) PEMT PF04191.13 KND97570.1 - 9.9e-34 115.9 2.8 2e-33 115.0 2.8 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase Vac_ImportDeg PF09783.9 KND97571.1 - 2.5e-53 180.2 0.1 3.1e-53 179.9 0.1 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein DUF3929 PF13066.6 KND97572.1 - 0.028 14.5 0.0 0.03 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3929) TFB6 PF17110.5 KND97574.1 - 3.2e-10 40.0 0.7 2.6e-09 37.0 0.0 2.4 2 1 0 2 2 2 1 Subunit 11 of the general transcription factor TFIIH DUF2267 PF10025.9 KND97575.1 - 0.023 15.0 0.0 0.045 14.0 0.1 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) UDG PF03167.19 KND97576.1 - 9.7e-11 41.9 0.0 1.4e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Brr6_like_C_C PF10104.9 KND97577.1 - 2.7e-45 153.4 0.4 4.1e-45 152.8 0.4 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Ion_trans PF00520.31 KND97577.1 - 0.0004 19.7 0.4 0.00058 19.2 0.4 1.2 1 0 0 1 1 1 1 Ion transport protein DUF3959 PF13105.6 KND97577.1 - 0.017 14.6 0.2 0.03 13.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) DUF4446 PF14584.6 KND97577.1 - 0.26 11.3 3.1 0.29 11.1 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Sugarporin_N PF11471.8 KND97577.1 - 0.63 10.0 2.8 1.2 9.2 0.8 2.2 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Fungal_trans_2 PF11951.8 KND97579.1 - 1.5e-10 40.5 0.5 1.9e-09 36.8 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND97579.1 - 1.5e-07 31.4 7.4 2.7e-07 30.6 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_membrane PF00664.23 KND97580.1 - 3.3e-36 125.4 16.6 4.1e-36 125.1 16.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KND97580.1 - 1.2e-08 35.5 0.0 2.5e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KND97580.1 - 8.7e-06 25.7 0.0 2.2e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 KND97580.1 - 0.00022 21.2 0.0 0.00042 20.3 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_23 PF13476.6 KND97580.1 - 0.00032 21.3 0.0 0.00058 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KND97580.1 - 0.00054 19.6 0.0 0.0015 18.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KND97580.1 - 0.003 18.0 0.0 0.0073 16.7 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 KND97580.1 - 0.0072 16.1 0.1 0.011 15.5 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KND97580.1 - 0.016 15.2 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KND97580.1 - 0.021 15.1 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KND97580.1 - 0.079 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SMC_N PF02463.19 KND97580.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KND97580.1 - 0.13 12.1 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 KND97580.1 - 0.13 12.7 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KND97580.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain HR_lesion PF05514.11 KND97580.1 - 1 9.6 5.0 1.2 9.3 0.4 2.6 3 0 0 3 3 3 0 HR-like lesion-inducing ABC_membrane PF00664.23 KND97581.1 - 1.1e-47 163.0 15.7 1.7e-47 162.4 15.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KND97581.1 - 1.9e-31 109.4 0.0 6.1e-27 94.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KND97581.1 - 3.5e-08 33.1 1.7 0.016 14.7 0.1 3.3 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KND97581.1 - 7.7e-08 32.5 0.0 0.0015 18.4 0.0 3.2 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KND97581.1 - 0.0067 16.2 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KND97581.1 - 0.035 14.4 1.1 3.2 8.0 0.1 3.2 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 KND97581.1 - 0.047 13.9 0.0 13 6.1 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 KND97581.1 - 0.055 13.6 0.0 0.23 11.6 0.0 2.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 KND97581.1 - 0.057 14.0 0.0 0.16 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain ThiF PF00899.21 KND97582.1 - 8.7e-108 359.3 0.0 6.6e-75 251.6 0.0 2.3 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KND97582.1 - 3.5e-91 305.6 0.7 5.8e-91 304.9 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 KND97582.1 - 6.1e-36 123.0 0.1 1.4e-35 121.9 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 KND97582.1 - 3.5e-28 97.6 0.1 7.7e-28 96.5 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KND97582.1 - 4e-25 87.8 1.8 1.1e-24 86.4 1.8 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Thioredoxin PF00085.20 KND97583.1 - 3e-16 59.3 0.4 5.5e-12 45.6 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KND97583.1 - 1.3e-06 28.5 3.0 4e-06 26.9 0.6 2.9 4 0 0 4 4 4 1 Thioredoxin-like domain O-antigen_lig PF13425.6 KND97583.1 - 0.14 10.9 1.2 0.31 9.8 1.2 1.5 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Hexapep PF00132.24 KND97584.1 - 1.1e-11 44.0 11.7 5e-05 22.9 0.4 4.7 4 1 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KND97584.1 - 6.7e-05 22.5 7.6 0.065 13.0 0.7 3.0 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase PMI_typeI PF01238.21 KND97585.1 - 1.6e-152 508.0 0.0 1.9e-152 507.8 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 KND97585.1 - 0.022 14.7 0.0 0.26 11.2 0.0 2.3 2 0 0 2 2 2 0 AraC-like ligand binding domain Cupin_2 PF07883.11 KND97585.1 - 0.096 12.4 0.1 2.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Cupin domain RRM_1 PF00076.22 KND97586.1 - 5.1e-15 55.1 0.0 7.7e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KND97586.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif GRP PF07172.11 KND97586.1 - 0.45 11.2 14.2 0.21 12.3 10.7 1.9 2 0 0 2 2 2 0 Glycine rich protein family API5 PF05918.11 KND97586.1 - 2.5 6.8 8.2 0.79 8.5 4.4 1.9 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Nop16 PF09420.10 KND97587.1 - 6.5e-49 166.8 12.1 8.4e-49 166.5 12.1 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 KTI12 PF08433.10 KND97587.1 - 0.038 13.4 1.7 0.069 12.6 1.0 1.7 1 1 1 2 2 2 0 Chromatin associated protein KTI12 Integrin_b_cyt PF08725.11 KND97587.1 - 0.044 13.5 1.0 0.1 12.3 0.1 2.1 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain DUF4337 PF14235.6 KND97587.1 - 8.5 6.5 8.2 0.4 10.8 0.7 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4337) ParA PF10609.9 KND97588.1 - 1.7e-95 319.1 0.2 2.1e-95 318.9 0.2 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KND97588.1 - 5.4e-11 42.7 0.0 1.5e-10 41.2 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KND97588.1 - 7.9e-08 32.4 0.2 4e-07 30.1 0.2 2.0 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 KND97588.1 - 2.5e-07 30.3 0.0 2.2e-06 27.2 0.0 2.2 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 KND97588.1 - 3.5e-06 26.4 0.2 3.2e-05 23.3 0.2 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 KND97588.1 - 0.00011 21.8 0.0 0.00017 21.1 0.0 1.3 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 KND97588.1 - 0.0021 17.7 0.2 0.0042 16.7 0.2 1.4 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KND97588.1 - 0.0035 16.4 0.3 0.0056 15.7 0.3 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_26 PF13500.6 KND97588.1 - 0.011 15.6 0.1 3 7.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 KND97588.1 - 0.012 15.1 0.1 0.022 14.2 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family APS_kinase PF01583.20 KND97588.1 - 0.032 14.1 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 KND97588.1 - 0.035 13.4 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 KND97588.1 - 0.16 12.4 0.2 0.32 11.4 0.2 1.5 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KND97588.1 - 0.28 11.0 0.9 0.69 9.8 0.9 1.6 1 0 0 1 1 1 0 RsgA GTPase Use1 PF09753.9 KND97589.1 - 0.0039 16.9 0.0 0.0045 16.7 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Syntaxin_2 PF14523.6 KND97589.1 - 0.02 15.3 1.5 0.54 10.7 0.4 2.0 2 0 0 2 2 2 0 Syntaxin-like protein DUF2105 PF09878.9 KND97589.1 - 0.43 10.3 3.3 0.56 9.9 3.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2105) VHS PF00790.19 KND97591.1 - 5e-09 36.1 0.0 1.1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KND97591.1 - 0.0062 16.8 0.1 0.022 15.0 0.1 2.0 1 1 0 1 1 1 1 GAT domain Mito_fiss_reg PF05308.11 KND97591.1 - 6.6 6.7 11.1 1.8 8.6 4.0 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator GTP_EFTU PF00009.27 KND97593.1 - 4.4e-44 150.3 0.0 8.6e-44 149.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KND97593.1 - 2.4e-34 118.0 0.3 2.4e-34 118.0 0.3 2.3 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KND97593.1 - 3.6e-08 33.7 0.3 9.5e-08 32.3 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KND97593.1 - 0.0017 18.4 0.1 0.012 15.7 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Peptidase_U32_C PF16325.5 KND97593.1 - 0.049 13.9 0.1 0.14 12.5 0.1 1.8 1 0 0 1 1 1 0 Peptidase family U32 C-terminal domain Ndc1_Nup PF09531.10 KND97593.1 - 2.5 6.7 9.1 4.4 5.9 9.1 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF908 PF06012.12 KND97593.1 - 9.7 5.5 9.2 13 5.0 9.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) IPK PF03770.16 KND97594.1 - 1e-51 175.6 0.0 1.3e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Syntaxin PF00804.25 KND97597.1 - 2.9e-22 79.3 19.0 2.9e-22 79.3 19.0 1.6 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 KND97597.1 - 5.5e-14 51.9 1.1 2e-13 50.1 1.1 2.0 1 0 0 1 1 1 1 SNARE domain Pox_EPC_I2-L1 PF12575.8 KND97597.1 - 0.019 15.2 1.8 0.23 11.7 0.1 2.7 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 GP57 PF17594.2 KND97597.1 - 0.068 12.9 0.3 3.8 7.3 0.2 2.5 2 0 0 2 2 2 0 Phage Tail fiber assembly helper gene product 57 PBP1_TM PF14812.6 KND97597.1 - 0.071 13.5 0.4 0.25 11.7 0.0 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF805 PF05656.14 KND97597.1 - 0.24 11.8 0.4 0.37 11.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF805) NAPRTase_N PF17767.1 KND97597.1 - 0.65 10.4 7.5 15 6.0 0.4 3.1 2 1 0 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF948 PF06103.11 KND97597.1 - 1.3 9.3 9.4 1.4 9.2 1.5 3.4 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 KND97597.1 - 3.9 7.5 13.9 5 7.2 1.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3394 PF11874.8 KND97597.1 - 5.8 6.6 7.9 1.7 8.3 3.7 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF3394) Syntaxin_2 PF14523.6 KND97597.1 - 7.3 7.0 23.3 0.49 10.8 12.3 2.8 1 1 2 3 3 3 0 Syntaxin-like protein Transp_cyt_pur PF02133.15 KND97598.1 - 1.2e-60 205.6 42.1 1.5e-60 205.2 42.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin HEAT PF02985.22 KND97599.1 - 0.035 14.3 1.3 52 4.5 0.0 5.4 8 0 0 8 8 8 0 HEAT repeat GIT_CC PF16559.5 KND97599.1 - 0.048 13.5 4.0 0.17 11.8 4.0 2.1 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Pinin_SDK_N PF04697.13 KND97599.1 - 4.4 7.9 14.0 0.84 10.3 3.7 3.3 3 0 0 3 3 3 0 pinin/SDK conserved region ETF PF01012.21 KND97600.1 - 1.1e-41 142.7 0.5 1.3e-41 142.5 0.5 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain KAP_NTPase PF07693.14 KND97601.1 - 3.7e-06 26.4 0.0 3.7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.6 KND97601.1 - 0.00017 22.0 0.1 0.00046 20.6 0.0 1.7 2 1 0 2 2 2 1 AAA ATPase domain PRK PF00485.18 KND97601.1 - 0.00072 19.4 0.0 0.0017 18.1 0.0 1.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Sigma54_activ_2 PF14532.6 KND97601.1 - 0.002 18.2 0.0 0.0033 17.6 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain cobW PF02492.19 KND97601.1 - 0.0025 17.4 0.0 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Torsin PF06309.11 KND97601.1 - 0.0036 17.4 0.0 0.0068 16.5 0.0 1.4 1 0 0 1 1 1 1 Torsin T2SSE PF00437.20 KND97601.1 - 0.011 14.9 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.22 KND97601.1 - 0.022 14.0 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 KND97601.1 - 0.025 14.3 0.0 0.47 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KND97601.1 - 0.03 13.6 0.0 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 KND97601.1 - 0.031 14.2 0.0 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 KND97601.1 - 0.037 14.5 0.0 0.063 13.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter MobB PF03205.14 KND97601.1 - 0.053 13.4 0.0 3.5 7.5 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Virul_Fac PF10139.9 KND97601.1 - 0.056 11.7 0.0 0.089 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative bacterial virulence factor AAA_14 PF13173.6 KND97601.1 - 0.07 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KND97601.1 - 0.099 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Adeno_IVa2 PF02456.15 KND97601.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein RNA_helicase PF00910.22 KND97601.1 - 0.12 12.8 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 KND97601.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KND97601.1 - 0.19 12.0 0.8 3.9 7.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain Proteasome PF00227.26 KND97602.1 - 3e-47 160.6 0.2 3.4e-47 160.4 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Oxidored_FMN PF00724.20 KND97605.1 - 7e-98 328.0 0.0 8.3e-98 327.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ELM2 PF01448.24 KND97605.1 - 0.23 12.2 0.8 0.51 11.1 0.8 1.6 1 0 0 1 1 1 0 ELM2 domain GATase PF00117.28 KND97606.1 - 0.096 12.4 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Pro_isomerase PF00160.21 KND97607.1 - 8.3e-40 136.6 0.1 1.2e-39 136.1 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KND97608.1 - 8.8e-16 57.5 0.2 1.8e-15 56.5 0.0 1.6 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4111 PF13427.6 KND97608.1 - 0.1 12.8 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) Ribophorin_I PF04597.14 KND97609.1 - 3.7e-104 349.4 1.1 4.2e-104 349.2 1.1 1.0 1 0 0 1 1 1 1 Ribophorin I Peptidase_A22B PF04258.13 KND97612.1 - 4.3e-57 193.8 6.1 8.3e-57 192.9 6.1 1.4 1 1 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 KND97612.1 - 1e-07 31.7 2.1 1e-07 31.7 2.1 2.6 4 0 0 4 4 4 1 Signal-peptide peptidase, presenilin aspartyl protease LRR19-TM PF15176.6 KND97612.1 - 1.4 9.0 5.5 11 6.1 3.4 2.4 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain Oxidored_FMN PF00724.20 KND97613.1 - 2.9e-88 296.4 0.0 3.3e-88 296.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Phasin_2 PF09361.10 KND97613.1 - 0.11 12.7 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 Phasin protein Dynamin_M PF01031.20 KND97615.1 - 1.6e-106 355.7 0.0 2.9e-106 354.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KND97615.1 - 4.7e-48 163.4 0.0 4.7e-48 163.4 0.0 2.1 3 0 0 3 3 3 1 Dynamin family GED PF02212.18 KND97615.1 - 5.1e-29 100.3 5.4 1.4e-28 98.9 5.4 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain RF-1 PF00472.20 KND97615.1 - 0.046 13.7 0.9 0.12 12.3 0.9 1.7 1 0 0 1 1 1 0 RF-1 domain Mesd PF10185.9 KND97615.1 - 0.084 12.8 0.3 0.29 11.0 0.4 1.8 2 0 0 2 2 2 0 Chaperone for wingless signalling and trafficking of LDL receptor Saw1 PF11561.8 KND97616.1 - 7.8e-10 38.7 3.8 5e-09 36.1 1.3 2.4 2 1 0 2 2 2 1 Single strand annealing-weakened 1 G-7-MTase PF12803.7 KND97616.1 - 0.02 14.1 0.1 0.025 13.8 0.1 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) PMSI1 PF15322.6 KND97616.1 - 0.17 11.3 0.1 0.23 10.9 0.1 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative DIOX_N PF14226.6 KND97624.1 - 1.6e-17 64.3 0.1 3.3e-17 63.3 0.1 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KND97624.1 - 9.8e-17 61.3 0.0 1.9e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAS_I_H PF18314.1 KND97626.1 - 4.6e-73 245.2 0.4 9e-73 244.2 0.4 1.5 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 KND97626.1 - 1.9e-72 242.9 0.0 1.1e-71 240.5 0.0 2.3 3 0 0 3 3 3 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 KND97626.1 - 2e-21 76.7 0.1 4e-21 75.8 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 KND97626.1 - 4.1e-17 62.3 0.1 9.2e-17 61.2 0.1 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 KND97626.1 - 5.1e-13 49.1 0.0 1.5e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 KND97626.1 - 1.5e-06 27.8 0.0 1.1e-05 25.0 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KND97626.1 - 0.0039 17.1 0.0 0.016 15.2 0.0 2.0 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KND97626.1 - 0.063 13.9 0.0 0.29 11.7 0.0 2.1 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MnmE_helical PF12631.7 KND97626.1 - 0.23 11.6 2.4 13 5.9 0.4 2.6 2 0 0 2 2 2 0 MnmE helical domain Sec7 PF01369.20 KND97628.1 - 3.4e-73 245.2 0.1 1.4e-72 243.2 0.1 2.2 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KND97628.1 - 1.4e-42 145.3 3.2 1.4e-42 145.3 3.2 3.7 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KND97628.1 - 2.5e-31 107.4 0.7 2.5e-31 107.4 0.7 4.6 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) DCB PF16213.5 KND97628.1 - 7.6e-08 32.2 2.3 1.9e-07 30.9 0.1 2.7 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Stb3 PF10330.9 KND97630.1 - 4.1e-29 100.5 0.0 8.3e-29 99.5 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein MCM PF00493.23 KND97631.1 - 4.4e-101 336.7 0.0 1.1e-100 335.4 0.0 1.6 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KND97631.1 - 1.9e-31 108.5 0.2 3.4e-31 107.7 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KND97631.1 - 1.1e-21 77.1 0.3 2.8e-21 75.7 0.3 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KND97631.1 - 1.1e-15 58.1 1.9 3.8e-15 56.4 1.9 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KND97631.1 - 3.2e-08 33.2 0.1 2.2e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KND97631.1 - 3.2e-06 27.2 0.0 1.4e-05 25.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KND97631.1 - 0.033 14.1 0.0 0.093 12.6 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KND97631.1 - 0.1 12.3 0.1 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.6 KND97631.1 - 0.13 12.6 0.5 2.4 8.5 0.0 2.8 2 1 0 3 3 3 0 AAA ATPase domain Mg_chelatase_C PF13335.6 KND97631.1 - 0.18 12.4 0.4 0.63 10.7 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal DUF202 PF02656.15 KND97632.1 - 3.3e-17 62.7 1.9 3.3e-17 62.7 1.9 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF202) Oxidored_q2 PF00420.24 KND97632.1 - 0.061 13.0 1.8 0.12 12.0 1.8 1.5 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L CopD PF05425.13 KND97632.1 - 2 8.9 9.7 1.1 9.7 5.3 2.2 1 1 1 2 2 2 0 Copper resistance protein D Tho1_MOS11_C PF18592.1 KND97633.1 - 3e-23 81.4 1.7 6.3e-23 80.3 1.7 1.6 1 0 0 1 1 1 1 Tho1/MOS11 C-terminal domain SAP PF02037.27 KND97633.1 - 2.2e-11 43.2 0.6 4.3e-11 42.3 0.6 1.5 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 KND97633.1 - 0.0013 18.4 0.4 0.0042 16.8 0.4 1.9 1 1 0 1 1 1 1 HeH/LEM domain Usp PF00582.26 KND97633.1 - 0.48 10.9 9.7 0.71 10.4 8.9 1.8 1 1 1 2 2 2 0 Universal stress protein family FGF-BP1 PF06473.12 KND97633.1 - 1.4 8.7 9.6 2.2 8.1 9.6 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Presenilin PF01080.17 KND97633.1 - 2.5 6.8 4.1 2.9 6.6 4.1 1.0 1 0 0 1 1 1 0 Presenilin TauD PF02668.16 KND97634.1 - 7.7e-57 193.1 1.0 1e-56 192.7 1.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.6 KND97634.1 - 0.085 13.8 0.2 0.22 12.4 0.0 1.8 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Peptidase_M1 PF01433.20 KND97635.1 - 3.8e-76 255.5 0.5 8.7e-76 254.3 0.5 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KND97635.1 - 3.2e-52 177.4 2.2 6.6e-52 176.4 2.2 1.6 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 KND97635.1 - 1.1e-51 176.2 0.9 2.1e-51 175.3 0.9 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Asn_synthase PF00733.21 KND97636.1 - 1.7e-88 297.7 0.1 3.7e-47 161.7 0.1 2.0 1 1 1 2 2 2 2 Asparagine synthase CSN8_PSD8_EIF3K PF10075.9 KND97638.1 - 9.9e-14 51.5 1.0 9.9e-14 51.5 1.0 1.6 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KND97638.1 - 0.0006 19.3 0.3 0.001 18.5 0.3 1.3 1 0 0 1 1 1 1 SAC3/GANP family VPS28 PF03997.12 KND97639.1 - 5.1e-60 202.4 1.0 6.4e-60 202.1 1.0 1.1 1 0 0 1 1 1 1 VPS28 protein DUF1400 PF07176.11 KND97639.1 - 0.043 14.1 0.3 0.091 13.0 0.3 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) Sod_Fe_C PF02777.18 KND97639.1 - 0.061 13.5 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, C-terminal domain Gag_p30 PF02093.16 KND97639.1 - 0.11 12.0 0.0 0.29 10.6 0.0 1.7 1 1 1 2 2 2 0 Gag P30 core shell protein ISG65-75 PF11727.8 KND97639.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Invariant surface glycoprotein Arrestin_C PF02752.22 KND97640.1 - 0.0001 22.8 0.0 0.00025 21.5 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Steroid_dh PF02544.16 KND97641.1 - 8.6e-11 42.0 15.4 8.6e-11 42.0 15.4 2.4 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase MFS_1 PF07690.16 KND97642.1 - 2.1e-08 33.5 38.4 4e-05 22.7 14.8 3.2 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF3671 PF12420.8 KND97642.1 - 8.4 6.5 14.8 0.6 10.2 4.4 3.3 3 0 0 3 3 3 0 Protein of unknown function Transp_cyt_pur PF02133.15 KND97643.1 - 6.2e-65 219.7 41.1 7.8e-65 219.4 41.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NADH_u_ox_C PF12853.7 KND97644.1 - 2.7e-47 158.7 1.5 3.9e-47 158.1 1.5 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.9 KND97644.1 - 5.9e-28 97.4 0.2 8.8e-28 96.8 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Mpv17_PMP22 PF04117.12 KND97647.1 - 4.1e-19 68.6 2.8 4.1e-19 68.6 2.8 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family POC1 PF10450.9 KND97648.1 - 1.3e-07 30.9 0.0 1.5e-07 30.6 0.0 1.2 1 1 0 1 1 1 1 POC1 chaperone COQ9 PF08511.11 KND97650.1 - 5.3e-25 87.0 0.3 8e-25 86.4 0.3 1.3 1 0 0 1 1 1 1 COQ9 Prefoldin_2 PF01920.20 KND97651.1 - 9.5e-23 80.2 12.0 1.2e-22 79.9 12.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit UPF0270 PF06794.12 KND97651.1 - 0.022 14.8 2.7 0.32 11.1 0.6 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) Herpes_UL14 PF03580.14 KND97651.1 - 0.034 14.4 0.7 0.034 14.4 0.7 2.0 2 0 0 2 2 2 0 Herpesvirus UL14-like protein MIP-T3_C PF17749.1 KND97651.1 - 0.04 13.9 1.8 0.04 13.9 1.8 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region DUF1192 PF06698.11 KND97651.1 - 0.044 13.9 0.9 0.044 13.9 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) ABC_tran_CTD PF16326.5 KND97651.1 - 0.066 13.5 15.3 0.22 11.8 4.2 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF5082 PF16888.5 KND97651.1 - 0.24 11.7 11.4 9.3 6.5 9.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Tropomyosin_1 PF12718.7 KND97651.1 - 0.24 11.6 11.0 0.52 10.5 11.0 1.6 1 1 0 1 1 1 0 Tropomyosin like DUF1664 PF07889.12 KND97651.1 - 0.29 11.2 8.2 0.85 9.7 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) THOC7 PF05615.13 KND97651.1 - 0.57 10.5 13.8 0.3 11.4 2.5 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 PspA_IM30 PF04012.12 KND97651.1 - 0.61 9.6 14.0 0.91 9.1 11.4 1.8 1 1 1 2 2 2 0 PspA/IM30 family FlaC_arch PF05377.11 KND97651.1 - 4.2 7.8 8.9 5.6 7.4 0.8 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Prefoldin PF02996.17 KND97651.1 - 4.5 7.2 12.1 4.2 7.3 1.8 2.3 1 1 1 2 2 2 0 Prefoldin subunit Spc24 PF08286.11 KND97651.1 - 5.6 7.3 11.4 2.1 8.6 2.3 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 RNA_pol_3_Rpc31 PF11705.8 KND97652.1 - 0.0018 18.5 12.0 0.0029 17.9 12.0 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.11 KND97652.1 - 0.073 12.7 8.4 0.099 12.2 8.4 1.2 1 0 0 1 1 1 0 PPP4R2 SGT1 PF07093.11 KND97652.1 - 0.11 10.9 4.8 0.11 10.9 4.8 1.1 1 0 0 1 1 1 0 SGT1 protein Nop14 PF04147.12 KND97652.1 - 0.44 8.7 14.6 0.45 8.7 14.6 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KND97652.1 - 0.49 8.6 10.4 0.6 8.3 10.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 KND97652.1 - 0.95 7.5 2.5 1.2 7.2 2.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EBV-NA3 PF05009.12 KND97652.1 - 5.4 6.5 5.5 7.9 5.9 5.5 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) PRELI PF04707.14 KND97653.1 - 5.9e-34 117.2 0.1 6.8e-34 117.0 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family Gemini_AL1_M PF08283.11 KND97653.1 - 0.03 14.4 0.7 0.076 13.1 0.1 1.9 2 0 0 2 2 2 0 Geminivirus rep protein central domain AA_permease PF00324.21 KND97654.1 - 2.8e-121 405.4 29.8 3.2e-121 405.2 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND97654.1 - 9.6e-38 130.1 35.8 1.1e-37 129.9 35.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF21 PF01595.20 KND97655.1 - 5.7e-33 114.1 0.0 1.1e-32 113.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KND97655.1 - 0.0032 17.9 0.0 2 8.9 0.0 2.9 2 0 0 2 2 2 2 CBS domain ATR13 PF16829.5 KND97655.1 - 0.14 12.5 0.1 3.6 8.0 0.0 2.9 3 0 0 3 3 3 0 Avirulence protein ATR13, RxLR effector SWIRM-assoc_2 PF16496.5 KND97655.1 - 0.68 8.7 7.8 1.1 8.1 7.8 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Pkinase PF00069.25 KND97657.1 - 1.3e-50 172.2 0.0 2.2e-50 171.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND97657.1 - 3.2e-23 82.3 0.0 4.7e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND97657.1 - 0.00021 20.7 0.0 0.0032 16.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KND97657.1 - 0.0015 18.2 0.4 0.05 13.2 0.1 2.3 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 SCAB_CC PF16712.5 KND97657.1 - 0.024 14.5 0.9 0.043 13.6 0.9 1.3 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein Kdo PF06293.14 KND97657.1 - 0.039 13.3 0.2 0.071 12.4 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND97657.1 - 0.052 13.5 0.2 0.1 12.5 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KND97657.1 - 0.47 9.3 4.8 0.54 9.2 0.2 2.2 1 1 0 2 2 2 0 Haspin like kinase domain TRAPP PF04051.16 KND97658.1 - 0.027 14.2 0.0 0.027 14.2 0.0 1.0 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component Solute_trans_a PF03619.16 KND97659.1 - 2e-72 243.9 5.9 2.6e-72 243.6 5.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha mIF3 PF14877.6 KND97660.1 - 4.9e-48 163.1 0.4 4.9e-48 163.1 0.4 1.9 2 0 0 2 2 2 1 Mitochondrial translation initiation factor Fungal_trans PF04082.18 KND97661.1 - 2.2e-32 112.1 4.3 2.2e-32 112.1 4.3 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain GTP_cyclohydro2 PF00925.20 KND97664.1 - 9.5e-56 187.9 0.0 1.4e-55 187.3 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Fer4 PF00037.27 KND97667.1 - 2.1e-14 52.6 15.4 3.5e-08 32.9 4.1 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KND97667.1 - 6.6e-13 49.0 9.6 1.4e-12 48.0 9.6 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KND97667.1 - 2e-10 40.6 21.1 2.6e-07 30.7 11.7 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KND97667.1 - 2.8e-10 41.0 10.9 3.9e-05 24.5 1.4 2.3 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 KND97667.1 - 9.9e-10 38.4 21.0 3.6e-08 33.5 10.1 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KND97667.1 - 1.4e-09 38.0 31.1 3.8e-06 26.9 11.8 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.6 KND97667.1 - 2.5e-08 34.2 5.9 7.9e-05 23.0 0.8 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 KND97667.1 - 5.7e-07 29.3 10.7 0.0041 17.1 2.3 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 KND97667.1 - 1.5e-06 28.0 17.5 0.00038 20.4 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KND97667.1 - 2.6e-05 24.4 12.1 0.00048 20.4 2.5 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KND97667.1 - 0.00022 21.7 12.6 0.025 15.1 2.3 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 KND97667.1 - 0.022 15.3 14.5 0.37 11.4 3.6 2.7 2 1 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 KND97667.1 - 0.053 14.5 15.7 0.11 13.5 3.5 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 KND97667.1 - 0.095 12.8 5.5 0.32 11.1 0.4 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S c-SKI_SMAD_bind PF08782.10 KND97667.1 - 0.2 11.9 6.6 2.3 8.5 0.3 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 KND97667.1 - 0.2 11.9 10.1 1.6 8.9 1.4 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 KND97667.1 - 0.26 12.1 11.5 0.65 10.9 1.3 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain ABC2_membrane PF01061.24 KND97668.1 - 6.9e-88 293.5 40.8 6.1e-44 150.0 15.1 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KND97668.1 - 1.5e-38 132.4 0.0 5.5e-19 69.0 0.1 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KND97668.1 - 7.2e-31 105.9 6.4 2.5e-28 97.8 0.1 3.5 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KND97668.1 - 3.6e-16 59.6 0.0 8e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KND97668.1 - 4.2e-09 36.0 19.1 6.9e-05 22.1 5.6 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KND97668.1 - 1.3e-07 31.6 0.2 4e-05 23.6 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KND97668.1 - 1.5e-06 27.9 0.2 0.00044 19.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KND97668.1 - 3.5e-05 24.3 0.1 0.00074 19.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KND97668.1 - 5.4e-05 23.5 0.1 0.024 14.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KND97668.1 - 0.00035 20.4 0.1 0.067 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KND97668.1 - 0.00088 19.3 0.2 0.29 11.2 0.2 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KND97668.1 - 0.0012 19.4 0.0 0.038 14.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KND97668.1 - 0.0021 18.3 0.1 0.57 10.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KND97668.1 - 0.0026 17.5 1.4 0.066 13.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 KND97668.1 - 0.0026 17.2 0.1 0.11 11.9 0.0 2.8 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 KND97668.1 - 0.0029 17.9 1.3 0.024 14.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KND97668.1 - 0.0053 16.7 1.0 0.72 9.8 0.2 3.0 3 0 0 3 3 3 1 NACHT domain cobW PF02492.19 KND97668.1 - 0.0093 15.6 1.4 0.29 10.7 0.4 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KND97668.1 - 0.011 16.2 0.1 1.5 9.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain COesterase PF00135.28 KND97668.1 - 0.012 14.5 0.2 0.019 13.8 0.2 1.2 1 0 0 1 1 1 0 Carboxylesterase family AAA_21 PF13304.6 KND97668.1 - 0.018 14.9 0.9 2.6 7.8 0.3 2.5 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NTPase_1 PF03266.15 KND97668.1 - 0.038 13.9 0.8 0.45 10.4 0.0 2.8 3 0 0 3 3 3 0 NTPase dNK PF01712.19 KND97668.1 - 0.053 13.4 0.0 0.8 9.5 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase ABC_ATPase PF09818.9 KND97668.1 - 0.06 12.1 0.1 0.59 8.9 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class RNA_helicase PF00910.22 KND97668.1 - 0.067 13.6 0.0 2.7 8.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 KND97668.1 - 0.074 12.8 0.0 0.61 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KND97668.1 - 0.09 13.2 0.1 3.6 8.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 KND97668.1 - 0.15 11.4 0.1 6.9 5.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Glyco_hydro_47 PF01532.20 KND97670.1 - 6.9e-111 371.4 0.0 8.8e-111 371.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Fcf1 PF04900.12 KND97670.1 - 0.12 12.7 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Fcf1 Aminotran_4 PF01063.19 KND97671.1 - 5.4e-40 137.6 0.0 6.6e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Mo25 PF08569.11 KND97672.1 - 1.1e-104 350.4 13.1 1.2e-104 350.2 13.1 1.0 1 0 0 1 1 1 1 Mo25-like Pkip-1 PF06878.11 KND97672.1 - 0.65 10.1 8.6 0.12 12.5 0.4 2.7 3 0 0 3 3 3 0 Pkip-1 protein EAP30 PF04157.16 KND97674.1 - 4.9e-24 84.9 0.0 8.3e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 KND97674.1 - 6.8e-22 77.5 0.1 2.2e-21 75.9 0.1 1.9 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 KND97674.1 - 8.3e-18 63.5 0.7 8.3e-18 63.5 0.7 2.5 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain DZR PF12773.7 KND97674.1 - 0.00045 20.2 4.0 0.002 18.1 0.7 2.4 2 0 0 2 2 2 1 Double zinc ribbon zf-RanBP PF00641.18 KND97674.1 - 0.19 11.1 12.4 0.047 13.0 1.3 3.3 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others zinc_ribbon_15 PF17032.5 KND97674.1 - 1.2 10.0 7.2 3.2 8.6 7.2 1.8 1 1 0 1 1 1 0 zinc-ribbon family zf-Sec23_Sec24 PF04810.15 KND97674.1 - 1.4 9.1 8.3 4.7 7.3 0.6 2.7 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-ribbon_3 PF13248.6 KND97674.1 - 9.2 5.8 6.2 3.1 7.3 1.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain SSF PF00474.17 KND97675.1 - 4.3e-19 68.7 26.6 7.9e-19 67.8 26.6 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Amidase PF01425.21 KND97676.1 - 9.7e-91 305.0 0.1 1.3e-90 304.5 0.1 1.2 1 0 0 1 1 1 1 Amidase CT_A_B PF02626.15 KND97676.1 - 5.7e-90 301.5 0.0 1.1e-89 300.6 0.0 1.5 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 KND97676.1 - 7.1e-61 205.4 0.0 1.8e-60 204.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CT_C_D PF02682.16 KND97676.1 - 2.5e-44 151.5 0.0 4.7e-44 150.6 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_N PF00289.22 KND97676.1 - 2.6e-42 143.8 0.2 8.3e-42 142.2 0.2 2.0 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KND97676.1 - 1.9e-32 111.6 0.0 5.5e-32 110.1 0.0 1.9 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KND97676.1 - 6.1e-17 61.2 4.0 1.1e-16 60.3 2.9 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KND97676.1 - 3.8e-10 39.6 0.0 7.7e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KND97676.1 - 1.9e-05 24.3 0.0 4.9e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KND97676.1 - 0.00019 21.5 0.0 0.00049 20.2 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.6 KND97676.1 - 0.0037 17.2 0.2 0.0085 16.0 0.2 1.6 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain NQRA PF05896.11 KND97676.1 - 0.0074 15.8 0.3 0.014 14.9 0.3 1.3 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATP-grasp_5 PF13549.6 KND97676.1 - 0.0082 15.6 0.0 0.024 14.1 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain Glyco_trans_1_4 PF13692.6 KND97676.1 - 0.021 15.2 2.5 0.092 13.2 0.6 3.0 3 0 0 3 3 2 0 Glycosyl transferases group 1 DUF5101 PF17031.5 KND97676.1 - 0.097 12.8 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5101) Biotin_lipoyl_2 PF13533.6 KND97676.1 - 0.29 11.0 4.3 4 7.3 0.1 2.8 2 1 1 3 3 3 0 Biotin-lipoyl like Hat1_N PF10394.9 KND97677.1 - 9.1e-39 133.3 0.1 1.5e-38 132.5 0.1 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 KND97677.1 - 0.00082 19.6 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KND97677.1 - 0.052 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pil1 PF13805.6 KND97679.1 - 4.1e-124 413.3 0.9 5e-124 413.0 0.9 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 AATF-Che1 PF13339.6 KND97679.1 - 0.049 14.3 0.4 0.11 13.2 0.2 1.6 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor PCP_red PF08369.10 KND97679.1 - 0.19 12.0 6.8 7.3 6.9 0.6 3.7 3 0 0 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit Nop10p PF04135.12 KND97679.1 - 0.22 11.6 3.4 3.9 7.6 0.1 2.4 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family HIP1_clath_bdg PF16515.5 KND97679.1 - 2.6 8.7 7.4 3.7 8.2 2.0 2.6 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Rad21_Rec8_N PF04825.13 KND97680.1 - 1.6e-17 63.7 0.0 2.6e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KND97680.1 - 8.3e-05 21.8 0.0 0.0002 20.6 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein E1_DerP2_DerF2 PF02221.15 KND97681.1 - 9.6e-27 94.0 0.3 1.1e-26 93.8 0.3 1.1 1 0 0 1 1 1 1 ML domain Sulfate_transp PF00916.20 KND97682.1 - 7.2e-75 252.1 22.0 1.2e-74 251.4 22.0 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KND97682.1 - 1.6e-10 40.6 0.1 3.8e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.29 KND97682.1 - 0.0024 17.9 0.0 0.0051 16.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PCDO_beta_N PF12391.8 KND97682.1 - 0.097 12.3 0.5 0.17 11.5 0.5 1.4 1 0 0 1 1 1 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal GCOM2 PF15328.6 KND97682.1 - 0.14 12.5 0.2 0.25 11.7 0.2 1.3 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 PA PF02225.22 KND97683.1 - 6.8e-05 22.8 0.0 0.00015 21.7 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M28 PF04389.17 KND97683.1 - 0.00056 19.7 0.0 0.00097 18.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Shadoo PF14999.6 KND97683.1 - 0.042 13.9 0.1 0.073 13.2 0.1 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective MFS_1 PF07690.16 KND97684.1 - 4.5e-13 48.9 33.4 6e-12 45.2 33.4 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KND97684.1 - 2.4e-07 29.6 18.2 2.1e-06 26.5 8.6 2.4 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) TMEM43 PF07787.12 KND97684.1 - 0.2 11.0 3.5 5.3 6.3 0.4 2.4 2 0 0 2 2 2 0 Transmembrane protein 43 TssN PF17555.2 KND97684.1 - 2.3 7.6 6.4 0.13 11.7 0.4 2.0 2 0 0 2 2 2 0 Type VI secretion system, TssN SH3_1 PF00018.28 KND97685.1 - 5.3e-05 22.7 0.3 0.00071 19.1 0.0 2.4 1 1 1 2 2 2 1 SH3 domain SH3_9 PF14604.6 KND97685.1 - 0.05 13.5 0.2 0.88 9.5 0.2 2.5 1 1 1 2 2 2 0 Variant SH3 domain hSH3 PF14603.6 KND97685.1 - 0.85 10.1 3.7 1.8 9.1 0.0 2.6 2 0 0 2 2 2 0 Helically-extended SH3 domain HEAT_EZ PF13513.6 KND97686.1 - 1.2e-20 73.6 17.8 3.1e-10 40.3 0.0 10.0 9 3 3 12 12 11 3 HEAT-like repeat HEAT_2 PF13646.6 KND97686.1 - 8.8e-17 61.3 11.7 0.011 16.1 0.1 9.2 5 3 2 8 8 8 4 HEAT repeats HEAT PF02985.22 KND97686.1 - 2.1e-15 55.5 29.1 0.0051 17.0 0.0 11.7 13 0 0 13 13 11 3 HEAT repeat Vac14_Fab1_bd PF12755.7 KND97686.1 - 7.6e-12 45.7 0.2 0.0059 17.2 0.0 5.0 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KND97686.1 - 9e-11 42.1 2.4 0.002 18.2 0.0 5.4 4 2 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KND97686.1 - 1.2e-06 28.3 1.6 0.63 9.6 0.0 5.4 4 1 0 4 4 4 2 CLASP N terminal IBN_N PF03810.19 KND97686.1 - 1.9e-05 24.5 0.2 0.00018 21.4 0.0 2.8 4 0 0 4 4 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 KND97686.1 - 0.00064 18.4 2.2 0.14 10.7 0.0 3.8 3 1 0 4 4 4 1 Adaptin N terminal region Arm PF00514.23 KND97686.1 - 0.0048 16.9 7.6 24 5.2 0.0 6.2 7 0 0 7 7 6 0 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 KND97686.1 - 0.01 15.0 0.4 3.3 6.7 0.0 4.1 5 0 0 5 5 5 0 RNAPII transcription regulator C-terminal RIX1 PF08167.12 KND97686.1 - 0.017 14.9 0.7 34 4.1 0.0 5.2 5 2 0 5 5 5 0 rRNA processing/ribosome biogenesis UME PF08064.13 KND97686.1 - 0.042 13.8 0.3 23 5.0 0.0 4.2 3 1 1 4 4 4 0 UME (NUC010) domain RTP1_C1 PF10363.9 KND97686.1 - 0.079 13.2 0.4 35 4.6 0.0 4.7 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 MFAP1 PF06991.11 KND97686.1 - 0.11 12.4 6.6 0.24 11.2 6.6 1.5 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing HEAT_PBS PF03130.16 KND97686.1 - 0.46 11.3 3.5 1.2e+02 3.8 0.0 5.4 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Bravo_FIGEY PF13882.6 KND97686.1 - 2.9 9.3 7.6 1.6 10.1 4.5 2.2 2 0 0 2 2 1 0 Bravo-like intracellular region Cwf_Cwc_15 PF04889.12 KND97686.1 - 4.2 7.0 15.3 8.6 6.0 15.3 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PIG-P PF08510.12 KND97687.1 - 1.9e-35 121.4 5.7 2.3e-35 121.1 5.7 1.1 1 0 0 1 1 1 1 PIG-P CPSase_L_D2 PF02786.17 KND97688.1 - 2e-110 367.3 0.0 5.6e-84 280.9 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KND97688.1 - 2e-39 134.7 0.0 5.6e-39 133.2 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KND97688.1 - 1.2e-21 77.0 0.0 1.8e-09 37.4 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KND97688.1 - 9.6e-18 64.5 0.1 1.3e-08 34.6 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KND97688.1 - 1.4e-10 41.0 0.0 0.00021 21.0 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 KND97688.1 - 4.6e-06 26.3 0.1 0.034 13.6 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 KND97688.1 - 5.8e-05 22.8 0.0 0.42 10.2 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.19 KND97688.1 - 0.00054 19.8 0.0 0.067 13.0 0.0 2.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 KND97688.1 - 0.0012 18.9 0.1 1.1 9.3 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain TrkA_N PF02254.18 KND97688.1 - 0.032 14.5 2.2 0.085 13.1 0.0 2.8 4 0 0 4 4 3 0 TrkA-N domain MGS PF02142.22 KND97688.1 - 0.043 14.0 0.0 0.16 12.2 0.0 2.1 1 0 0 1 1 1 0 MGS-like domain Epimerase PF01370.21 KND97688.1 - 0.15 11.5 0.0 0.48 9.8 0.0 1.8 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family SNAP PF14938.6 KND97689.1 - 7e-101 337.4 8.1 7.9e-101 337.2 8.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_14 PF13428.6 KND97689.1 - 4e-05 24.1 0.8 3.2 8.8 0.1 4.2 3 1 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KND97689.1 - 4.1e-05 23.5 9.9 0.0075 16.4 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KND97689.1 - 4.1e-05 23.4 15.8 0.17 12.1 0.0 5.5 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KND97689.1 - 5.9e-05 23.3 4.7 0.07 13.4 1.6 3.2 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 KND97689.1 - 8.6e-05 22.2 16.5 0.073 12.9 1.6 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat DUF410 PF04190.13 KND97689.1 - 0.00016 21.6 4.1 0.0011 18.9 3.7 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF410) TPR_MalT PF17874.1 KND97689.1 - 0.0014 18.1 0.0 0.0038 16.6 0.0 1.4 1 1 0 1 1 1 1 MalT-like TPR region TPR_6 PF13174.6 KND97689.1 - 0.002 18.7 6.6 0.39 11.4 0.6 4.3 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KND97689.1 - 0.0022 17.9 4.9 0.19 11.9 0.1 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.9 KND97689.1 - 0.0032 17.2 2.4 0.3 10.8 0.8 3.1 1 1 1 2 2 2 1 26S proteasome subunit RPN7 TPR_16 PF13432.6 KND97689.1 - 0.0081 16.8 2.0 1.1 10.0 0.0 3.1 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KND97689.1 - 0.02 15.4 2.7 1.2 9.7 0.3 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KND97689.1 - 0.052 13.9 0.4 0.86 10.1 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Imm49 PF15575.6 KND97689.1 - 0.097 12.4 1.0 0.13 12.0 0.1 1.6 2 0 0 2 2 2 0 Immunity protein 49 Foie-gras_1 PF11817.8 KND97689.1 - 0.11 12.1 0.5 1.3 8.5 0.1 2.2 1 1 1 2 2 2 0 Foie gras liver health family 1 MIT PF04212.18 KND97689.1 - 0.72 10.0 6.4 5.8 7.1 0.2 3.9 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 KND97689.1 - 2.3 7.9 7.4 39 4.0 0.3 4.1 4 0 0 4 4 4 0 TPR repeat NSF PF02071.20 KND97689.1 - 2.4 9.3 12.3 8.4 7.7 0.1 5.9 7 0 0 7 7 6 0 Aromatic-di-Alanine (AdAR) repeat ANAPC3 PF12895.7 KND97689.1 - 2.6 8.3 7.4 5.9 7.2 0.3 3.3 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4320 PF14208.6 KND97691.1 - 0.018 15.1 0.1 0.019 15.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) DASH_Dad4 PF08650.10 KND97691.1 - 0.021 14.8 0.5 0.025 14.5 0.5 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad4 DUF4781 PF16013.5 KND97691.1 - 0.092 11.5 0.2 0.11 11.3 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) KIP1 PF07765.12 KND97691.1 - 0.19 11.8 3.9 0.28 11.3 3.8 1.3 1 1 0 1 1 1 0 KIP1-like protein Nnf1 PF03980.14 KND97692.1 - 7.2e-21 74.6 3.7 1.5e-20 73.6 3.7 1.5 1 0 0 1 1 1 1 Nnf1 HALZ PF02183.18 KND97692.1 - 2.6 8.3 8.5 0.25 11.6 1.0 3.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper Ribosomal_S15 PF00312.22 KND97693.1 - 3.6e-25 88.0 0.2 3.6e-25 88.0 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein S15 DP PF08781.10 KND97693.1 - 0.028 14.3 0.6 0.079 12.9 0.6 1.8 1 0 0 1 1 1 0 Transcription factor DP PseudoU_synth_2 PF00849.22 KND97695.1 - 2.7e-23 82.8 0.0 5e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase GATA PF00320.27 KND97698.1 - 9.3e-15 54.0 4.5 2.4e-14 52.7 4.5 1.8 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 KND97698.1 - 0.0032 16.9 0.5 0.0061 16.0 0.5 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Pox_A_type_inc PF04508.12 KND97698.1 - 1.1 9.3 5.9 12 5.9 0.0 2.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Pyocin_S PF06958.12 KND97698.1 - 1.1 9.8 5.2 0.28 11.7 0.7 2.3 2 0 0 2 2 2 0 S-type Pyocin Spt20 PF12090.8 KND97698.1 - 3.5 7.2 24.5 1.4 8.5 8.6 2.3 2 0 0 2 2 2 0 Spt20 family Vfa1 PF08432.10 KND97698.1 - 5.7 7.2 11.8 0.098 13.0 4.2 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Macoilin PF09726.9 KND97698.1 - 8.6 4.8 21.5 0.048 12.2 11.7 1.9 2 0 0 2 2 2 0 Macoilin family PGM_PMM_I PF02878.16 KND97699.1 - 4e-36 123.8 0.3 6.6e-36 123.1 0.3 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KND97699.1 - 6.8e-25 87.5 0.0 1.6e-24 86.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KND97699.1 - 1.1e-13 51.7 0.0 6.5e-13 49.2 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KND97699.1 - 1.2e-08 35.0 0.0 3e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Med19 PF10278.9 KND97700.1 - 0.51 10.2 10.6 0.54 10.2 10.6 1.0 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Aminotran_1_2 PF00155.21 KND97701.1 - 8.6e-81 271.9 0.0 9.8e-81 271.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4250 PF14056.6 KND97701.1 - 0.025 14.5 0.5 0.066 13.2 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) CHDNT PF08073.12 KND97701.1 - 0.032 14.2 0.1 0.6 10.1 0.0 2.7 3 0 0 3 3 3 0 CHDNT (NUC034) domain ADH_zinc_N PF00107.26 KND97704.1 - 8.5e-24 84.0 0.0 1.4e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KND97704.1 - 7.4e-14 52.9 0.1 6.7e-13 49.8 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KND97704.1 - 3.2e-10 39.8 0.0 7.2e-10 38.7 0.0 1.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KND97704.1 - 0.027 13.9 0.1 0.047 13.1 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Sugar_tr PF00083.24 KND97705.1 - 2.1e-149 498.2 32.9 2.4e-149 498.1 32.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND97705.1 - 1.2e-29 103.4 31.6 5.1e-27 94.7 12.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KND97705.1 - 0.004 15.5 0.4 0.004 15.5 0.4 3.2 1 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Snurportin1 PF11538.8 KND97706.1 - 2.4 8.4 5.6 0.27 11.4 1.4 1.6 2 0 0 2 2 2 0 Snurportin1 Sugar_tr PF00083.24 KND97707.1 - 3.3e-154 514.1 30.9 3.8e-154 513.9 30.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND97707.1 - 2.4e-29 102.4 27.5 1.6e-26 93.1 13.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KND97707.1 - 0.00056 18.5 1.8 0.0012 17.4 1.8 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RAMP4 PF06624.12 KND97707.1 - 0.058 13.5 0.0 0.058 13.5 0.0 2.0 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Ni_hydr_CYTB PF01292.20 KND97707.1 - 0.084 12.5 8.5 2.5 7.7 3.1 3.6 4 1 1 5 5 5 0 Prokaryotic cytochrome b561 DUF4293 PF14126.6 KND97707.1 - 1.5 9.0 10.9 1.9 8.7 1.5 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) Bmt2 PF11968.8 KND97711.1 - 5.7e-85 284.6 0.0 7.3e-85 284.3 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 UPF0697 PF15117.6 KND97711.1 - 0.13 12.3 0.1 2.7 8.1 0.1 2.9 3 0 0 3 3 3 0 Uncharacterised protein family UPF0697 DEAD PF00270.29 KND97713.1 - 6.5e-39 133.5 0.0 1.4e-38 132.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND97713.1 - 5.2e-28 97.6 0.0 3.8e-27 94.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KND97713.1 - 0.00089 19.5 0.0 0.003 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain DDHD PF02862.17 KND97713.1 - 0.067 13.3 0.2 0.067 13.3 0.2 1.9 2 0 0 2 2 2 0 DDHD domain CPSF100_C PF13299.6 KND97713.1 - 3.4 7.8 13.9 1 9.5 7.1 2.9 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 KND97713.1 - 4.2 6.0 7.8 7.2 5.3 7.8 1.3 1 0 0 1 1 1 0 Presenilin eRF1_2 PF03464.15 KND97715.1 - 2.5e-46 157.3 0.1 4.3e-46 156.5 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KND97715.1 - 1.1e-35 122.5 0.1 2.3e-35 121.5 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KND97715.1 - 1e-18 67.6 0.0 1.6e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 KND97715.1 - 1.5e-11 44.7 0.0 2.3e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 KND97715.1 - 2.3e-10 40.8 0.1 3.5e-10 40.3 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor Tnp_DNA_bind PF14706.6 KND97715.1 - 0.0054 16.5 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Transposase DNA-binding CDC50 PF03381.15 KND97717.1 - 2.8e-84 282.9 1.8 3.8e-84 282.5 1.8 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Pkinase PF00069.25 KND97720.1 - 4.3e-63 213.1 0.0 1.2e-62 211.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND97720.1 - 1.7e-44 152.1 0.0 3.5e-44 151.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND97720.1 - 0.0011 18.3 0.3 0.0031 16.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KND97720.1 - 0.0015 17.4 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KND97720.1 - 0.035 13.7 0.0 1.1 8.8 0.0 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pex2_Pex12 PF04757.14 KND97721.1 - 7.2e-38 130.4 8.9 9.3e-38 130.0 8.9 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 KND97721.1 - 5.3e-05 23.1 6.1 0.0001 22.1 6.1 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KND97721.1 - 0.00036 20.3 6.9 0.0012 18.7 7.0 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KND97721.1 - 0.00073 19.7 3.4 0.00073 19.7 3.4 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KND97721.1 - 0.0021 18.3 6.1 0.0046 17.3 6.1 1.6 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KND97721.1 - 0.0038 17.1 6.8 0.0081 16.0 6.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KND97721.1 - 0.0047 16.7 4.8 0.011 15.6 4.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KND97721.1 - 0.0049 16.9 3.7 0.0097 15.9 3.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KND97721.1 - 0.33 11.3 5.0 0.55 10.6 5.0 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KND97721.1 - 0.41 10.5 5.9 0.96 9.3 5.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 KND97721.1 - 1.5 8.8 10.0 0.43 10.5 5.6 2.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KND97721.1 - 2.4 8.4 5.7 5.9 7.1 5.7 1.7 1 1 0 1 1 1 0 FYVE zinc finger IBR PF01485.21 KND97721.1 - 3.9 7.8 5.8 1.2 9.4 2.6 1.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain WD40 PF00400.32 KND97722.1 - 4.9e-08 33.5 2.0 0.27 12.2 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat HPS3_N PF14761.6 KND97722.1 - 0.025 14.1 0.1 0.078 12.5 0.1 1.9 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 SART-1 PF03343.13 KND97723.1 - 2.6e-48 165.1 60.0 3.9e-34 118.2 48.6 3.7 2 1 1 3 3 3 3 SART-1 family Fucose_iso_N2 PF07882.12 KND97723.1 - 0.004 16.7 1.0 0.094 12.3 0.1 2.7 3 0 0 3 3 3 1 L-fucose isomerase, second N-terminal domain DUF150_C PF17384.2 KND97723.1 - 0.17 12.0 4.0 0.96 9.6 1.5 3.3 3 0 0 3 3 3 0 RimP C-terminal SH3 domain E1-E2_ATPase PF00122.20 KND97724.1 - 6.9e-45 152.8 0.3 6.9e-45 152.8 0.3 2.8 3 0 0 3 3 3 1 E1-E2 ATPase HMA PF00403.26 KND97724.1 - 1.1e-41 141.0 10.8 2.9e-14 53.3 0.4 4.0 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase PF00702.26 KND97724.1 - 8.6e-32 111.1 0.3 4e-31 108.9 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KND97724.1 - 0.00012 22.5 0.0 0.00042 20.8 0.0 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KND97724.1 - 0.0074 16.1 0.3 0.055 13.2 0.1 2.2 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HopW1-1 PF15457.6 KND97724.1 - 0.15 11.3 2.4 0.59 9.4 0.3 2.4 3 0 0 3 3 3 0 Type III T3SS secreted effector HopW1-1/HopPmaA SRP54_N PF02881.19 KND97725.1 - 0.47 10.7 0.1 0.47 10.7 0.1 3.6 3 2 0 3 3 3 0 SRP54-type protein, helical bundle domain Cadherin_tail PF15974.5 KND97727.1 - 9.9 6.5 9.8 6.1 7.2 0.3 2.1 1 1 1 2 2 2 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region Xpo1 PF08389.12 KND97730.1 - 3.3e-24 85.7 9.2 1.1e-23 84.0 5.3 3.3 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 KND97730.1 - 9.1e-06 25.5 0.5 0.00028 20.8 0.3 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain UME PF08064.13 KND97730.1 - 0.0048 16.8 1.4 2.3 8.2 0.1 3.7 3 0 0 3 3 3 2 UME (NUC010) domain HEAT PF02985.22 KND97730.1 - 0.063 13.6 0.1 28 5.3 0.0 4.3 5 0 0 5 5 5 0 HEAT repeat Peptidase_S66C PF17676.1 KND97730.1 - 0.15 12.6 0.0 0.45 11.1 0.0 1.8 1 0 0 1 1 1 0 LD-carboxypeptidase C-terminal domain Guanylate_kin PF00625.21 KND97731.1 - 6e-66 221.6 0.0 6.7e-66 221.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 KND97731.1 - 2.4e-07 31.3 0.0 4.4e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KND97731.1 - 1e-05 25.9 0.1 9.3e-05 22.8 0.0 2.3 2 1 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 KND97731.1 - 2.9e-05 24.3 0.1 0.00056 20.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KND97731.1 - 9.2e-05 23.0 0.2 0.00034 21.1 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KND97731.1 - 0.00043 20.6 0.0 0.00076 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KND97731.1 - 0.00058 19.6 0.5 0.0014 18.3 0.5 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KND97731.1 - 0.00062 20.0 0.0 0.002 18.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KND97731.1 - 0.00096 19.7 0.0 0.0013 19.3 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 KND97731.1 - 0.0017 17.9 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KND97731.1 - 0.0022 17.9 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 KND97731.1 - 0.0023 17.9 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain MMR_HSR1 PF01926.23 KND97731.1 - 0.0028 17.7 0.1 0.0051 16.9 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 KND97731.1 - 0.0031 17.2 0.0 0.0052 16.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KND97731.1 - 0.004 17.6 0.3 0.013 16.0 0.1 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KND97731.1 - 0.0049 16.8 0.0 0.0085 16.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 KND97731.1 - 0.0053 16.7 0.1 0.011 15.7 0.1 1.7 1 1 0 1 1 1 1 NTPase Viral_helicase1 PF01443.18 KND97731.1 - 0.0055 16.5 0.0 0.0092 15.7 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 KND97731.1 - 0.0067 16.5 0.0 0.011 15.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 KND97731.1 - 0.0069 15.5 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 KND97731.1 - 0.0076 16.0 0.4 0.019 14.7 0.1 1.8 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 KND97731.1 - 0.0097 15.9 0.0 0.054 13.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KND97731.1 - 0.01 15.8 0.3 0.019 14.9 0.3 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 KND97731.1 - 0.011 15.0 0.2 0.064 12.5 0.2 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_2 PF07724.14 KND97731.1 - 0.012 15.8 0.1 0.32 11.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) cobW PF02492.19 KND97731.1 - 0.023 14.3 0.1 0.065 12.8 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KND97731.1 - 0.035 14.0 0.0 0.086 12.7 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Adeno_IVa2 PF02456.15 KND97731.1 - 0.035 12.9 0.0 0.062 12.1 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein Cytidylate_kin PF02224.18 KND97731.1 - 0.059 13.1 0.1 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase AAA_17 PF13207.6 KND97731.1 - 0.1 13.1 0.3 0.56 10.6 0.0 2.2 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.6 KND97731.1 - 0.11 12.9 0.7 0.26 11.6 0.7 2.0 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KND97731.1 - 0.23 11.9 1.7 0.29 11.6 1.7 1.7 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 KND97734.1 - 9.7e-72 241.5 0.0 1.1e-71 241.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND97734.1 - 6.2e-28 97.8 0.0 9.7e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KND97734.1 - 8.6e-05 21.6 0.1 0.00021 20.3 0.1 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KND97734.1 - 0.00022 20.7 0.0 0.00035 20.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KND97734.1 - 0.0007 18.7 0.1 0.0012 18.0 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 KND97734.1 - 0.0027 17.6 0.1 0.0084 16.1 0.1 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KND97734.1 - 0.0049 16.3 0.3 0.012 15.0 0.3 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pyr_redox_2 PF07992.14 KND97736.1 - 7.2e-30 104.2 0.0 8.8e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KND97736.1 - 2.6e-08 34.3 0.3 2.1e-07 31.4 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KND97736.1 - 1.4e-05 25.2 1.6 0.051 13.6 0.0 3.4 3 1 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 KND97736.1 - 0.00037 19.7 0.0 0.00063 19.0 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KND97736.1 - 0.035 13.2 0.0 0.066 12.2 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein DUF5023 PF16426.5 KND97736.1 - 0.066 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5023) adh_short PF00106.25 KND97739.1 - 1.6e-35 122.4 0.2 2.2e-35 121.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND97739.1 - 4.2e-20 72.3 0.1 5.4e-20 71.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND97739.1 - 3e-05 24.0 0.1 0.00023 21.1 0.0 2.0 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KND97739.1 - 0.056 13.3 0.1 0.14 12.0 0.1 1.6 1 1 0 1 1 1 0 NAD(P)H-binding ApbA PF02558.16 KND97739.1 - 0.1 12.3 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Mitochondr_Som1 PF11093.8 KND97740.1 - 4.7e-21 74.6 1.7 7.3e-21 74.0 1.7 1.3 1 0 0 1 1 1 1 Mitochondrial export protein Som1 UQ_con PF00179.26 KND97741.1 - 1.8e-18 66.5 0.0 2.1e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KND97741.1 - 0.014 15.6 0.0 0.016 15.5 0.0 1.2 1 0 0 1 1 1 0 RWD domain MAD PF05557.13 KND97742.1 - 3.7e-19 68.6 66.6 6e-19 67.9 66.6 1.3 1 0 0 1 1 1 1 Mitotic checkpoint protein VPS9 PF02204.18 KND97742.1 - 0.012 15.8 2.5 5.4 7.3 0.3 3.4 2 0 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain JIP_LZII PF16471.5 KND97742.1 - 0.017 15.3 2.6 0.017 15.3 2.6 8.8 8 4 2 10 10 10 0 JNK-interacting protein leucine zipper II CSN5_C PF18323.1 KND97742.1 - 0.021 15.7 3.7 0.021 15.7 3.7 5.3 5 2 1 6 6 6 0 Cop9 signalosome subunit 5 C-terminal domain DUF4407 PF14362.6 KND97742.1 - 0.71 9.2 48.9 13 5.0 5.0 4.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) WXG100 PF06013.12 KND97742.1 - 4.4 7.6 10.3 3.3 8.0 0.1 4.8 5 0 0 5 5 5 0 Proteins of 100 residues with WXG PRP1_N PF06424.12 KND97743.1 - 4e-27 95.4 4.6 4e-27 95.4 4.6 3.8 3 1 0 3 3 3 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 KND97743.1 - 2e-20 71.7 8.0 0.072 13.9 1.7 10.7 6 4 5 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.6 KND97743.1 - 7.6e-13 48.8 16.0 0.02 15.4 0.4 7.7 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 KND97743.1 - 1.3e-06 28.4 4.8 1 9.9 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 KND97743.1 - 6.3e-05 23.5 0.3 5.6 7.7 0.0 4.9 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KND97743.1 - 7.2e-05 22.6 12.5 1.2 9.4 0.0 7.7 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 KND97743.1 - 0.0028 17.9 2.2 2.5 8.4 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KND97743.1 - 0.014 15.5 12.1 2.2 8.7 0.1 7.5 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 KND97743.1 - 0.019 14.8 1.7 56 3.8 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat IL32 PF15225.6 KND97743.1 - 0.025 14.9 0.3 0.11 12.9 0.1 2.2 2 1 0 2 2 2 0 Interleukin 32 Mad3_BUB1_I PF08311.12 KND97743.1 - 0.061 13.3 0.5 1.4 8.9 0.0 3.4 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 YcgR PF07317.12 KND97743.1 - 0.15 12.0 0.3 0.79 9.6 0.1 2.2 2 0 0 2 2 2 0 Flagellar regulator YcgR TPR_9 PF13371.6 KND97743.1 - 0.17 12.1 4.0 7.5 6.8 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat CAF1C_H4-bd PF12265.8 KND97744.1 - 1.1e-14 54.4 0.2 3e-14 53.0 0.0 1.9 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KND97744.1 - 3.3e-12 46.7 13.1 0.0016 19.2 0.1 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND97744.1 - 5.3e-07 29.8 1.6 0.01 16.1 0.3 3.4 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3246 PF11596.8 KND97744.1 - 0.0059 16.1 1.3 0.012 15.0 1.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) Myc_N PF01056.18 KND97744.1 - 0.013 15.4 0.2 0.021 14.7 0.2 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Kelch_4 PF13418.6 KND97745.1 - 1.8e-43 146.3 1.0 6.2e-09 35.7 0.0 6.8 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KND97745.1 - 1.9e-33 114.1 2.3 2.5e-09 37.2 0.0 7.1 7 1 0 7 7 7 4 Galactose oxidase, central domain DUF4110 PF13422.6 KND97745.1 - 1.4e-25 89.2 0.0 1.4e-25 89.2 0.0 4.4 4 1 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.6 KND97745.1 - 1.5e-22 79.1 3.7 3.4e-05 23.9 0.1 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 KND97745.1 - 2.5e-19 68.8 3.7 0.00098 19.1 0.1 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 KND97745.1 - 4.8e-15 54.9 7.0 1.1e-06 28.1 0.1 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 KND97745.1 - 4.7e-12 45.4 15.5 0.00034 20.5 0.2 6.2 6 1 0 6 6 6 4 Kelch motif BUD22 PF09073.10 KND97745.1 - 1.3 8.3 45.8 0.12 11.7 24.9 2.2 2 0 0 2 2 2 0 BUD22 DUF3597 PF12200.8 KND97745.1 - 3.4 8.2 8.1 1.1 9.8 3.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Retinin_C PF04527.12 KND97746.1 - 0.087 13.1 0.1 0.78 10.0 0.0 2.1 2 0 0 2 2 2 0 Drosophila Retinin like protein RrnaAD PF00398.20 KND97747.1 - 7.5e-69 231.7 0.0 9.4e-69 231.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KND97747.1 - 4.1e-06 27.4 0.0 1.3e-05 25.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND97747.1 - 0.00097 19.7 0.0 0.0029 18.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND97747.1 - 0.0027 18.4 0.0 0.006 17.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KND97747.1 - 0.0044 16.4 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KND97747.1 - 0.0044 16.6 0.0 0.0087 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KND97747.1 - 0.0051 16.6 0.0 0.0083 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 KND97747.1 - 0.0066 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_2 PF00891.18 KND97747.1 - 0.045 13.1 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_18 PF12847.7 KND97747.1 - 0.075 13.0 0.0 3.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 KND97747.1 - 0.09 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain KAR9 PF08580.10 KND97749.1 - 9.7e-51 173.1 6.6 7.6e-45 153.7 7.0 2.8 1 1 1 2 2 2 2 Yeast cortical protein KAR9 Myb_DNA-binding PF00249.31 KND97749.1 - 0.33 11.2 1.0 2 8.6 0.1 2.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain Ni_hydr_CYTB PF01292.20 KND97750.1 - 0.087 12.4 0.0 0.099 12.2 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 PGM_PMM_I PF02878.16 KND97751.1 - 5.1e-16 58.6 0.0 2.2e-08 33.9 0.0 2.7 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KND97751.1 - 1.8e-13 50.4 0.4 5.5e-13 48.9 0.4 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 KND97751.1 - 1.3e-05 25.8 1.1 0.00069 20.2 0.2 3.4 3 2 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KND97751.1 - 0.0041 17.3 0.0 0.015 15.5 0.0 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III CinA_KH PF18146.1 KND97751.1 - 0.0091 16.1 2.1 0.061 13.5 0.2 2.9 3 0 0 3 3 3 1 Damage-inducible protein CinA KH domain SNase PF00565.17 KND97753.1 - 4.3e-25 88.3 0.2 5.9e-25 87.8 0.2 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue EAF PF09816.9 KND97754.1 - 7.8e-10 39.1 0.0 2.2e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor TC1 PF15063.6 KND97754.1 - 0.088 12.7 0.2 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 Thyroid cancer protein 1 TMEM214 PF10151.9 KND97754.1 - 7.3 4.9 12.5 10 4.4 12.5 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Dynactin_p22 PF07426.11 KND97755.1 - 0.00023 21.1 4.3 0.00041 20.2 4.2 1.6 1 1 0 1 1 1 1 Dynactin subunit p22 DUF2969 PF11184.8 KND97755.1 - 0.024 15.0 0.1 0.75 10.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2969) DUF5076 PF16826.5 KND97755.1 - 0.11 12.4 0.9 1.4 8.9 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5076) SHE3 PF17078.5 KND97756.1 - 2.5e-58 197.5 30.0 3.8e-58 196.9 30.0 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 GAS PF13851.6 KND97756.1 - 3.7e-06 26.4 27.9 0.0085 15.5 8.3 3.2 2 1 1 3 3 3 3 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 KND97756.1 - 0.0086 15.9 22.7 0.025 14.4 6.8 3.0 1 1 2 3 3 3 2 Coiled-coil region of CCDC155 or KASH ZapB PF06005.12 KND97756.1 - 0.021 15.2 15.7 1.2e+02 3.3 0.0 4.4 2 1 0 2 2 2 0 Cell division protein ZapB PHA_synth_III_E PF09712.10 KND97756.1 - 0.022 13.9 2.1 0.043 12.9 1.5 1.7 1 1 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) DUF3450 PF11932.8 KND97756.1 - 0.025 13.9 17.3 1.1 8.5 2.0 3.8 1 1 2 4 4 4 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.21 KND97756.1 - 0.086 13.0 26.9 0.097 12.8 3.2 4.7 4 1 0 4 4 4 0 bZIP transcription factor ADIP PF11559.8 KND97756.1 - 0.35 10.9 24.3 0.16 12.0 3.9 3.5 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 KND97756.1 - 0.39 10.5 19.8 0.1 12.4 3.4 3.8 3 1 1 4 4 4 0 Septum formation initiator DUF1664 PF07889.12 KND97756.1 - 0.44 10.6 11.9 0.71 9.9 0.2 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) TLE_N PF03920.15 KND97756.1 - 0.46 10.6 6.1 0.27 11.3 1.0 2.6 1 1 1 3 3 3 0 Groucho/TLE N-terminal Q-rich domain Hemerythrin PF01814.23 KND97756.1 - 0.5 11.0 5.9 0.28 11.8 0.4 2.6 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain Jnk-SapK_ap_N PF09744.9 KND97756.1 - 1 9.6 20.1 0.12 12.6 12.7 2.8 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 KND97756.1 - 1.3 9.6 29.5 0.55 10.8 11.7 3.2 1 1 2 3 3 3 0 Apg6 coiled-coil region TMPIT PF07851.13 KND97756.1 - 1.6 7.9 16.5 0.59 9.3 3.9 2.8 1 1 2 3 3 3 0 TMPIT-like protein HAUS-augmin3 PF14932.6 KND97756.1 - 1.7 8.2 18.8 0.42 10.2 4.6 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DivIVA PF05103.13 KND97756.1 - 1.7 8.7 21.0 7.6 6.6 0.2 4.4 1 1 2 4 4 4 0 DivIVA protein UPF0242 PF06785.11 KND97756.1 - 1.8 8.6 27.3 0.16 12.1 7.3 3.2 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 KND97756.1 - 3.1 7.0 12.9 2e+02 1.1 12.9 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Tup_N PF08581.10 KND97756.1 - 3.3 8.1 13.2 7.6 6.9 4.6 3.5 2 1 1 3 3 3 0 Tup N-terminal FlaC_arch PF05377.11 KND97756.1 - 3.3 8.2 16.2 2.6 8.5 0.5 4.1 4 1 1 5 5 4 0 Flagella accessory protein C (FlaC) Cep57_CLD_2 PF14197.6 KND97756.1 - 4 7.6 24.6 8.6 6.5 0.9 4.5 3 1 0 4 4 4 0 Centrosome localisation domain of PPC89 TolA_bind_tri PF16331.5 KND97756.1 - 4.6 7.4 10.2 0.24 11.5 1.9 2.9 3 0 0 3 3 3 0 TolA binding protein trimerisation HIP1_clath_bdg PF16515.5 KND97756.1 - 4.8 7.9 21.0 11 6.8 0.3 4.0 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fungal_TACC PF12709.7 KND97756.1 - 4.9 7.7 20.3 2.9 8.4 0.9 4.2 3 1 2 5 5 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins SlyX PF04102.12 KND97756.1 - 5.5 7.7 13.6 5.4 7.7 0.3 4.9 2 1 4 6 6 6 0 SlyX BLOC1_2 PF10046.9 KND97756.1 - 5.5 7.4 20.4 1.8 8.9 2.7 4.1 1 1 4 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 KND97756.1 - 6.9 6.9 19.1 6.6 6.9 6.7 2.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family YabA PF06156.13 KND97756.1 - 7.5 7.3 21.8 2.3 8.9 3.5 4.0 1 1 2 3 3 3 0 Initiation control protein YabA Fez1 PF06818.15 KND97756.1 - 8.7 6.7 23.2 54 4.1 2.7 3.0 1 1 1 2 2 2 0 Fez1 WD40 PF00400.32 KND97757.1 - 5.4e-06 27.1 0.7 0.13 13.2 0.4 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Aminotran_5 PF00266.19 KND97759.1 - 5e-24 84.9 0.1 6.1e-24 84.7 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KND97759.1 - 0.00016 21.0 0.1 0.00022 20.5 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Baculo_LEF-11 PF06385.12 KND97759.1 - 0.1 13.1 0.1 0.2 12.1 0.1 1.4 1 0 0 1 1 1 0 Baculovirus LEF-11 protein DnaJ PF00226.31 KND97760.1 - 4e-20 71.7 1.7 1.4e-19 69.9 1.7 2.0 1 0 0 1 1 1 1 DnaJ domain HalX PF08663.10 KND97760.1 - 0.0019 18.5 0.5 2.4 8.5 0.1 2.7 2 0 0 2 2 2 2 HalX domain Recombinase PF07508.13 KND97760.1 - 0.025 14.9 1.2 5.1 7.5 0.0 2.8 2 1 1 3 3 3 0 Recombinase DNA_topoisoIV PF00521.20 KND97761.1 - 1.3e-126 423.0 0.1 1.3e-126 423.0 0.1 1.6 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KND97761.1 - 5.6e-50 168.9 0.3 2.4e-49 166.9 0.3 2.2 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KND97761.1 - 3.9e-26 91.6 5.2 8.4e-26 90.5 5.2 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KND97761.1 - 1.3e-14 54.6 0.1 4e-14 53.1 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KND97761.1 - 4.6e-07 30.0 0.0 1.6e-06 28.2 0.0 2.0 1 0 0 1 1 1 1 Toprim domain DUF2576 PF10845.8 KND97761.1 - 0.095 12.3 2.5 0.096 12.3 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) Presenilin PF01080.17 KND97764.1 - 2.1 7.0 4.7 3 6.5 4.7 1.2 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 KND97764.1 - 4 6.1 7.8 5.2 5.8 7.8 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Lin-8 PF03353.15 KND97764.1 - 6.7 6.2 12.4 12 5.3 12.4 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Rdx PF10262.9 KND97765.1 - 1.1e-08 35.2 0.0 1.7e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Rdx family DUF3017 PF11222.8 KND97766.1 - 0.045 14.0 0.6 0.052 13.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3017) GATA PF00320.27 KND97768.1 - 2.2e-16 59.1 5.3 4.2e-16 58.3 5.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 KND97768.1 - 1e-07 31.7 4.4 2.5e-07 30.4 4.4 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.12 KND97768.1 - 0.17 11.4 1.9 0.18 11.3 0.4 1.8 2 0 0 2 2 2 0 TFIIB zinc-binding DUF3984 PF13136.6 KND97771.1 - 0.0057 16.1 0.9 0.0074 15.7 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) CUE PF02845.16 KND97772.1 - 5.9e-10 38.7 0.1 2.2e-09 36.8 0.0 1.9 2 0 0 2 2 2 1 CUE domain SARAF PF06682.12 KND97772.1 - 1.1 8.8 7.3 14 5.2 7.0 2.2 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Presenilin PF01080.17 KND97772.1 - 2.8 6.6 15.9 6.9 5.3 10.6 2.1 2 0 0 2 2 2 0 Presenilin NDUF_B7 PF05676.13 KND97774.1 - 4.6e-13 48.7 2.1 5.6e-13 48.4 2.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) UPF0203 PF05254.12 KND97774.1 - 0.071 13.4 0.6 0.071 13.4 0.6 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) COX6B PF02297.17 KND97774.1 - 0.64 10.3 6.5 13 6.1 6.4 2.0 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb GATA PF00320.27 KND97779.1 - 3.2e-16 58.6 5.3 5.4e-16 57.9 5.3 1.4 1 0 0 1 1 1 1 GATA zinc finger Nudix_N_2 PF14803.6 KND97779.1 - 0.028 14.3 2.8 0.057 13.3 2.8 1.5 1 0 0 1 1 1 0 Nudix N-terminal Zn-ribbon_8 PF09723.10 KND97779.1 - 0.75 10.0 2.7 0.63 10.2 0.5 2.0 2 0 0 2 2 2 0 Zinc ribbon domain Hydrolase_6 PF13344.6 KND97782.1 - 3.4e-22 78.5 0.0 6e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KND97782.1 - 3.8e-20 71.7 0.0 2.2e-19 69.3 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KND97782.1 - 0.0017 18.7 0.0 5.8 7.1 0.0 3.4 3 1 1 4 4 4 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KND97782.1 - 0.12 12.5 0.0 2.3 8.3 0.0 2.6 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase TP_methylase PF00590.20 KND97783.1 - 7e-45 153.6 0.0 2.2e-44 151.9 0.0 1.9 3 0 0 3 3 3 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 KND97783.1 - 7e-12 45.7 0.0 1.5e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KND97783.1 - 0.0007 19.2 0.2 0.057 13.1 0.2 2.4 1 1 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KND97783.1 - 0.0068 15.8 1.2 0.0084 15.5 0.0 1.8 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central ANAPC2 PF08672.11 KND97783.1 - 0.11 13.1 0.2 0.52 10.9 0.0 2.3 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 Tropomodulin PF03250.14 KND97784.1 - 0.015 15.4 0.1 0.016 15.3 0.1 1.0 1 0 0 1 1 1 0 Tropomodulin Nro1 PF12753.7 KND97785.1 - 1.1e-147 492.3 22.8 1.2e-145 485.6 22.8 2.0 1 1 0 1 1 1 1 Nuclear pore complex subunit Nro1 Acyltransferase PF01553.21 KND97787.1 - 1.9e-08 34.0 0.0 0.002 17.7 0.0 2.9 3 0 0 3 3 3 2 Acyltransferase CotJB PF12652.7 KND97787.1 - 0.43 10.8 1.9 0.4 10.9 0.1 1.9 2 0 0 2 2 2 0 CotJB protein TRAPP PF04051.16 KND97788.1 - 3.4e-31 107.9 0.1 4.1e-31 107.7 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component FA_hydroxylase PF04116.13 KND97790.1 - 3.4e-23 82.5 6.9 3.4e-23 82.5 6.9 2.1 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily Methyltransf_11 PF08241.12 KND97791.1 - 3.8e-18 65.9 0.0 6.5e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND97791.1 - 9.6e-16 58.3 0.0 1.9e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND97791.1 - 2.6e-11 43.5 0.0 4.3e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND97791.1 - 4.9e-10 40.0 0.0 1.1e-09 39.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KND97791.1 - 1.9e-07 30.7 0.0 2.7e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KND97791.1 - 1.6e-05 24.8 0.0 2.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KND97791.1 - 0.0013 18.3 0.0 0.0032 17.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KND97791.1 - 0.0016 17.8 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.12 KND97791.1 - 0.0068 15.5 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_32 PF13679.6 KND97791.1 - 0.017 15.1 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Pirin PF02678.16 KND97792.1 - 4.2e-24 84.6 0.2 9.5e-24 83.5 0.2 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 KND97792.1 - 2.2e-19 69.7 0.0 5e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Pirin C-terminal cupin domain CDC27 PF09507.10 KND97793.1 - 2.5e-19 70.0 32.3 7.2e-19 68.5 32.3 1.7 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 HTH_Tnp_ISL3 PF13542.6 KND97793.1 - 0.016 14.6 0.1 0.033 13.6 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Myelin_PLP PF01275.19 KND97796.1 - 0.22 11.4 0.5 0.32 10.8 0.5 1.1 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) PARG_cat PF05028.14 KND97798.1 - 0.0074 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) DUF3371 PF11851.8 KND97798.1 - 0.011 16.8 2.7 0.027 15.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) zf-C3HC4_3 PF13920.6 KND97798.1 - 0.62 10.0 6.4 1.4 8.9 3.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KND97798.1 - 1.8 9.0 9.8 8.2 6.9 9.8 2.0 1 1 0 1 1 1 0 Ring finger domain LURAP PF14854.6 KND97799.1 - 0.013 15.4 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 Leucine rich adaptor protein Pkinase PF00069.25 KND97801.1 - 1.2e-62 211.7 0.0 1.7e-62 211.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND97801.1 - 6.4e-35 120.7 0.0 1e-34 120.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KND97801.1 - 3.6e-05 22.7 0.0 7.1e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KND97801.1 - 0.0054 15.7 0.4 0.016 14.1 0.4 1.7 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KND97801.1 - 0.011 15.4 0.4 0.022 14.3 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Kinase-like PF14531.6 KND97801.1 - 0.035 13.4 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RskA PF10099.9 KND97801.1 - 0.073 13.4 4.0 0.12 12.7 4.0 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Seadorna_VP7 PF07387.11 KND97801.1 - 0.083 11.9 0.0 0.18 10.8 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 DUF4148 PF13663.6 KND97801.1 - 0.85 9.8 3.5 1.9 8.7 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Glyco_hydro_92 PF07971.12 KND97806.1 - 0.021 13.7 0.9 0.024 13.6 0.9 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 UPF0542 PF15086.6 KND97807.1 - 7.4 6.6 8.9 9 6.3 8.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 DUF5004 PF16395.5 KND97808.1 - 0.021 14.8 0.1 0.021 14.8 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5004) Ferlin_C PF16165.5 KND97808.1 - 0.043 13.8 4.3 0.046 13.7 4.3 1.0 1 0 0 1 1 1 0 Ferlin C-terminus TPR_12 PF13424.6 KND97809.1 - 0.00067 19.9 4.4 0.48 10.7 0.0 4.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KND97809.1 - 0.0087 16.1 1.8 3.6 7.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Peptidase_C97 PF05903.14 KND97809.1 - 0.01 15.7 0.1 0.02 14.7 0.1 1.4 1 0 0 1 1 1 0 PPPDE putative peptidase domain IFP_35_N PF07334.13 KND97809.1 - 0.078 13.1 2.2 0.17 12.0 0.3 2.4 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus TPR_1 PF00515.28 KND97809.1 - 0.11 12.4 4.3 2.1 8.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat FadA PF09403.10 KND97809.1 - 3.6 8.1 6.9 1.5 9.3 3.0 2.4 2 0 0 2 2 2 0 Adhesion protein FadA Adap_comp_sub PF00928.21 KND97810.1 - 1.6e-11 44.1 0.1 3.4e-11 43.0 0.0 1.5 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KND97810.1 - 4e-09 36.6 0.3 7e-09 35.8 0.2 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Glyco_hydro_38 PF18438.1 KND97810.1 - 0.041 13.9 0.0 0.18 11.8 0.0 2.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain 1 PDEase_II PF02112.15 KND97811.1 - 3.5e-61 207.2 0.0 2.1e-60 204.7 0.0 1.8 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 KND97811.1 - 8.7e-09 35.2 0.0 1.2e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KND97811.1 - 0.0077 16.2 0.1 0.012 15.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KND97811.1 - 0.042 13.3 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain zf-Di19 PF05605.12 KND97811.1 - 0.59 10.5 3.2 0.36 11.1 0.2 2.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Proteasome PF00227.26 KND97812.1 - 1e-26 93.6 0.0 1.3e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Trm5_N PF18093.1 KND97814.1 - 0.21 11.5 0.9 24 4.9 0.0 3.2 3 0 0 3 3 3 0 tRNA methyltransferase 5 N-terminal domain DUF410 PF04190.13 KND97815.1 - 3.4e-71 240.0 1.0 4.1e-71 239.8 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) DUF1175 PF06672.11 KND97815.1 - 0.096 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1175) NUDIX PF00293.28 KND97816.1 - 2.5e-12 47.0 0.1 3.2e-12 46.6 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain EF-hand_6 PF13405.6 KND97817.1 - 2.7e-09 36.2 0.1 0.0025 17.6 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KND97817.1 - 1.5e-07 31.8 0.2 0.00028 21.3 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KND97817.1 - 2.3e-06 26.7 0.3 3.6e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KND97817.1 - 9.1e-06 24.9 0.0 2.8e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KND97817.1 - 0.022 14.6 0.1 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair HABP4_PAI-RBP1 PF04774.15 KND97817.1 - 0.072 13.9 0.3 0.18 12.6 0.0 1.7 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family Peptidase_S24 PF00717.23 KND97818.1 - 4.5e-08 32.9 0.0 1.2e-07 31.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KND97818.1 - 0.00088 19.1 0.0 0.1 12.4 0.0 2.5 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 CX9C PF16860.5 KND97819.1 - 1.3e-24 85.9 14.3 4e-17 62.0 1.9 2.0 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 KND97819.1 - 3.9e-06 26.8 11.6 0.0015 18.6 4.3 2.7 2 1 0 2 2 2 2 CHCH domain COX6B PF02297.17 KND97819.1 - 0.00094 19.4 8.5 0.039 14.2 0.3 2.2 1 1 1 2 2 2 2 Cytochrome oxidase c subunit VIb MTCP1 PF08991.10 KND97819.1 - 0.0026 18.0 3.4 0.0026 18.0 3.4 2.0 2 1 0 2 2 2 1 Mature-T-Cell Proliferation I type NDUF_B7 PF05676.13 KND97819.1 - 0.055 13.2 9.5 0.064 13.0 1.9 2.2 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) UPF0203 PF05254.12 KND97819.1 - 0.076 13.3 10.0 21 5.5 0.2 3.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) COX17 PF05051.13 KND97819.1 - 0.21 12.0 11.9 0.46 10.9 1.6 3.5 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) GCK PF07802.11 KND97819.1 - 0.26 11.7 7.3 3.9 7.9 0.1 2.8 1 1 1 3 3 3 0 GCK domain DUF3128 PF11326.8 KND97819.1 - 5.1 7.5 10.4 11 6.4 2.5 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3128) LicD PF04991.13 KND97820.1 - 2.5e-26 93.3 1.0 3.8e-25 89.4 1.0 2.3 1 1 0 1 1 1 1 LicD family Folliculin PF11704.8 KND97821.1 - 5e-41 140.6 0.1 3.5e-40 137.9 0.1 1.9 1 1 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Atg14 PF10186.9 KND97822.1 - 9.9e-07 28.1 1.6 5.2e-06 25.8 1.6 1.8 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KND97822.1 - 1e-06 27.9 0.5 0.00034 19.6 0.1 2.3 2 0 0 2 2 2 2 Vacuolar protein sorting 38 DUF4470 PF14737.6 KND97822.1 - 0.062 13.5 0.1 0.18 12.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4470) MBT PF02820.18 KND97822.1 - 0.097 13.0 0.0 0.35 11.2 0.0 1.9 1 1 0 1 1 1 0 mbt repeat SRP1_TIP1 PF00660.17 KND97823.1 - 2.1e-18 66.2 0.0 2.7e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Seripauperin and TIP1 family UPF0126 PF03458.13 KND97823.1 - 0.0057 16.5 0.2 0.0057 16.5 0.2 2.2 2 0 0 2 2 2 1 UPF0126 domain Diphtheria_T PF02764.14 KND97823.1 - 0.14 12.1 0.3 4.1 7.4 0.1 2.2 1 1 1 2 2 2 0 Diphtheria toxin, T domain Bacteriocin_IIc PF10439.9 KND97823.1 - 2.6 8.2 10.2 2 8.6 4.0 2.2 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Serglycin PF04360.12 KND97823.1 - 3.3 7.6 9.4 4.2 7.3 7.5 1.8 1 1 0 2 2 2 0 Serglycin AF-4 PF05110.13 KND97823.1 - 5.7 4.9 7.5 5.3 5.0 7.5 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein VWA PF00092.28 KND97825.1 - 0.09 13.0 0.0 0.25 11.6 0.0 1.7 2 0 0 2 2 2 0 von Willebrand factor type A domain GPI2 PF06432.11 KND97826.1 - 5.9e-71 239.2 22.4 6.6e-71 239.0 22.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF5315 PF17242.2 KND97827.1 - 3.7e-18 65.1 4.1 1.1e-17 63.7 4.1 1.8 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) WXG100 PF06013.12 KND97827.1 - 0.074 13.3 3.1 3.4 8.0 1.0 2.7 2 0 0 2 2 2 0 Proteins of 100 residues with WXG QRPTase_C PF01729.19 KND97827.1 - 0.11 12.3 0.6 0.17 11.6 0.2 1.4 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain LMWPc PF01451.21 KND97827.1 - 0.29 11.5 4.4 0.47 10.8 0.1 2.2 1 1 1 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase Fzo_mitofusin PF04799.13 KND97827.1 - 0.67 9.5 4.4 4 7.0 0.0 2.5 1 1 0 2 2 2 0 fzo-like conserved region Mrpl_C PF18502.1 KND97827.1 - 0.68 10.2 5.4 0.69 10.2 3.0 2.1 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain Hexokinase_2 PF03727.16 KND97828.1 - 1.2e-78 263.9 0.0 1.7e-78 263.3 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KND97828.1 - 1.9e-73 246.6 0.0 2.8e-73 246.1 0.0 1.3 1 0 0 1 1 1 1 Hexokinase DUF1366 PF07104.11 KND97828.1 - 0.0092 15.7 0.1 12 5.7 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF1366) FGGY_N PF00370.21 KND97828.1 - 0.18 11.3 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain TOM13 PF08219.11 KND97829.1 - 3.4e-26 91.0 0.1 4.9e-26 90.5 0.1 1.4 1 1 0 1 1 1 1 Outer membrane protein TOM13 Rpr2 PF04032.16 KND97831.1 - 3.4e-23 81.7 2.4 4.4e-23 81.4 2.4 1.1 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Mut7-C PF01927.16 KND97831.1 - 0.015 15.4 0.4 0.019 15.1 0.4 1.1 1 0 0 1 1 1 0 Mut7-C RNAse domain CxC3 PF18804.1 KND97831.1 - 0.051 13.4 0.3 0.087 12.7 0.3 1.3 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases Proteasome PF00227.26 KND97832.1 - 5e-54 182.7 0.1 5.8e-54 182.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit TMEM51 PF15345.6 KND97832.1 - 0.033 14.0 0.9 0.054 13.3 0.9 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 IL6 PF00489.17 KND97832.1 - 0.043 13.4 0.3 0.07 12.7 0.3 1.3 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family XPG_I PF00867.18 KND97833.1 - 3e-27 94.8 0.0 5.5e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KND97833.1 - 2.5e-25 88.9 0.0 5.4e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KND97833.1 - 2.3e-08 34.5 0.0 9.5e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 KND97833.1 - 0.022 15.3 0.0 0.14 12.8 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH_2 PF12826.7 KND97833.1 - 0.065 13.3 0.1 0.26 11.4 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif Nucleoporin2 PF04096.14 KND97834.1 - 7.8e-45 152.6 0.0 1.3e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KND97834.1 - 1.2e-20 74.1 360.0 4.1e-09 37.2 35.7 11.0 3 3 6 9 9 9 7 Nucleoporin FG repeat region AP_endonuc_2 PF01261.24 KND97835.1 - 4.1e-31 108.1 0.0 6.8e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Telomere_reg-2 PF10193.9 KND97838.1 - 1.2e-28 99.7 4.5 3.5e-28 98.2 0.4 3.8 4 0 0 4 4 4 1 Telomere length regulation protein ABC2_membrane_3 PF12698.7 KND97839.1 - 0.17 11.0 11.1 0.22 10.6 11.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein FAM196 PF15265.6 KND97839.1 - 2.5 7.5 19.7 3.2 7.2 19.7 1.0 1 0 0 1 1 1 0 FAM196 family GREB1 PF15782.5 KND97839.1 - 3.5 4.6 12.8 4.2 4.4 12.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer XRN_M PF17846.1 KND97839.1 - 8 5.3 8.1 10 4.9 8.1 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Utp14 PF04615.13 KND97839.1 - 9.5 4.6 20.2 11 4.4 20.2 1.0 1 0 0 1 1 1 0 Utp14 protein Patatin PF01734.22 KND97839.1 - 10 6.3 21.2 2.9e+02 1.5 21.1 2.5 1 1 0 1 1 1 0 Patatin-like phospholipase TFR_dimer PF04253.15 KND97840.1 - 2.2e-23 82.7 0.5 5.5e-23 81.4 0.5 1.7 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KND97840.1 - 8.8e-21 74.5 0.0 1.5e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KND97840.1 - 1.2e-12 47.7 0.4 4.3e-12 45.9 0.4 1.9 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KND97840.1 - 0.0069 16.1 0.0 0.02 14.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KND97840.1 - 0.022 14.3 0.0 0.05 13.0 0.0 1.6 1 0 0 1 1 1 0 Nicastrin Synaptobrevin PF00957.21 KND97840.1 - 4.1 7.3 4.4 0.6 9.9 0.3 1.7 2 0 0 2 2 2 0 Synaptobrevin Zn_clus PF00172.18 KND97841.1 - 2.1e-06 27.7 13.0 4.2e-06 26.8 13.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KND97841.1 - 1.1e-05 24.4 3.3 0.0001 21.3 0.7 2.8 1 1 0 2 2 2 1 Fungal specific transcription factor domain Peptidase_M20 PF01546.28 KND97842.1 - 9.8e-33 113.6 0.0 1.4e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KND97842.1 - 0.00017 21.4 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.14 KND97842.1 - 0.00081 19.3 0.0 0.0034 17.3 0.0 2.1 2 1 0 2 2 2 1 Peptidase dimerisation domain SEA PF01390.20 KND97842.1 - 0.083 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 SEA domain MFS_1 PF07690.16 KND97843.1 - 1.5e-32 112.9 19.9 2.2e-32 112.4 19.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3792 PF12670.7 KND97843.1 - 0.016 15.3 0.9 0.016 15.3 0.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) Cytokin_check_N PF10407.9 KND97844.1 - 0.0083 16.1 0.9 0.046 13.7 0.1 2.2 2 0 0 2 2 2 1 Cdc14 phosphatase binding protein N-terminus TFIIB PF00382.19 KND97845.1 - 6.8e-43 144.6 0.6 6.2e-22 77.4 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KND97845.1 - 1.9e-12 46.5 1.5 3.6e-12 45.6 1.5 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 KND97845.1 - 0.008 16.2 0.3 0.021 14.9 0.2 1.6 1 1 0 1 1 1 1 Retinoblastoma-associated protein B domain FAM180 PF15173.6 KND97845.1 - 0.015 15.3 0.1 0.03 14.3 0.1 1.5 1 0 0 1 1 1 0 FAM180 family zf-ribbon_3 PF13248.6 KND97845.1 - 0.045 13.2 1.3 0.56 9.7 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain MFS_1 PF07690.16 KND97846.1 - 3.2e-21 75.6 39.6 1.7e-17 63.4 38.8 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 KND97846.1 - 0.00023 19.7 0.6 0.00023 19.7 0.6 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector DUF2976 PF11190.8 KND97846.1 - 0.37 10.6 8.5 0.26 11.1 0.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) Pox_A14 PF05767.12 KND97846.1 - 0.99 9.6 4.4 0.78 9.9 0.5 2.8 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Candida_ALS_N PF11766.8 KND97848.1 - 4.5e-64 216.1 2.6 4.5e-64 216.1 2.6 2.6 3 0 0 3 3 3 1 Cell-wall agglutinin N-terminal ligand-sugar binding Candida_ALS PF05792.13 KND97848.1 - 1.8e-10 41.2 29.8 2.4e-07 31.2 15.3 7.4 8 0 0 8 8 8 2 Candida agglutinin-like (ALS) Big_8 PF17961.1 KND97848.1 - 2.8e-06 27.4 0.1 2.8e-06 27.4 0.1 3.5 2 1 0 2 2 2 1 Bacterial Ig domain MFS_1 PF07690.16 KND97849.1 - 1e-15 57.6 24.4 1.4e-15 57.1 24.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KND97849.1 - 0.0028 16.6 0.8 0.0028 16.6 0.8 1.8 2 0 0 2 2 2 1 MFS_1 like family WD40 PF00400.32 KND97852.1 - 8.2e-25 86.6 14.4 1.6e-05 25.5 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND97852.1 - 2e-18 66.4 7.6 7.9e-07 29.3 0.2 4.4 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KND97852.1 - 2.3e-07 30.9 3.4 0.019 14.9 0.3 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KND97852.1 - 0.0064 15.5 0.0 0.065 12.2 0.0 2.2 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Aminotran_1_2 PF00155.21 KND97853.1 - 9.2e-20 71.1 0.0 1.1e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KND97853.1 - 0.007 15.7 0.0 0.0098 15.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase WD40 PF00400.32 KND97854.1 - 4.1e-29 100.2 6.5 3.6e-09 37.1 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND97854.1 - 7.5e-14 51.8 0.0 0.12 12.7 0.0 5.4 3 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 KND97854.1 - 7.7e-11 41.6 1.2 1.9e-10 40.4 1.2 1.7 1 0 0 1 1 1 1 HIRA B motif Hira PF07569.11 KND97854.1 - 4e-10 39.8 0.0 6.6e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 TUP1-like enhancer of split PD40 PF07676.12 KND97854.1 - 1e-05 25.3 0.1 8.7 6.4 0.0 4.8 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat IKI3 PF04762.12 KND97854.1 - 0.098 10.6 0.0 12 3.7 0.0 2.8 2 1 0 3 3 3 0 IKI3 family CHD5 PF04420.14 KND97855.1 - 1.4e-48 164.8 4.9 1.7e-48 164.5 4.9 1.1 1 0 0 1 1 1 1 CHD5-like protein CK_II_beta PF01214.18 KND97856.1 - 1.8e-64 216.9 0.0 2.4e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit HSCB_C PF07743.13 KND97857.1 - 3.6e-18 65.8 5.9 1.1e-17 64.3 2.5 2.5 3 0 0 3 3 3 1 HSCB C-terminal oligomerisation domain PolyA_pol PF01743.20 KND97857.1 - 0.061 13.8 0.0 0.086 13.3 0.0 1.3 1 0 0 1 1 1 0 Poly A polymerase head domain DnaJ PF00226.31 KND97857.1 - 0.061 13.5 0.1 0.29 11.3 0.0 2.1 2 0 0 2 2 2 0 DnaJ domain Sec23_trunk PF04811.15 KND97860.1 - 2.5e-65 220.4 0.0 3.5e-65 220.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KND97860.1 - 2.2e-31 108.4 0.2 4.8e-31 107.4 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KND97860.1 - 3.4e-22 78.2 0.0 6.7e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 KND97860.1 - 3.1e-14 52.6 0.0 6.7e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 KND97860.1 - 7e-13 48.4 2.5 1.4e-12 47.5 2.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 KND97860.1 - 0.0055 16.1 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-RanBP PF00641.18 KND97860.1 - 0.0067 15.7 0.1 0.013 14.8 0.1 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF3895 PF13034.6 KND97862.1 - 0.14 12.2 0.0 0.35 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3895) HDA2-3 PF11496.8 KND97863.1 - 2.9e-100 335.2 2.9 2.9e-100 335.2 2.9 2.0 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 HMMR_N PF15905.5 KND97863.1 - 0.00039 20.0 26.9 0.0023 17.5 13.4 2.2 2 0 0 2 2 2 2 Hyaluronan mediated motility receptor N-terminal THOC7 PF05615.13 KND97863.1 - 0.03 14.6 20.1 0.043 14.1 5.5 3.4 2 1 1 3 3 3 0 Tho complex subunit 7 PMEI PF04043.15 KND97863.1 - 0.058 13.7 1.5 0.15 12.4 1.5 1.6 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor DUF3932 PF13068.6 KND97863.1 - 0.089 13.1 0.2 0.28 11.5 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3932) Spc7 PF08317.11 KND97863.1 - 0.17 10.7 26.9 0.63 8.9 26.5 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein DHR10 PF18595.1 KND97863.1 - 0.18 11.8 27.6 0.35 10.9 10.2 2.6 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain MerR-DNA-bind PF09278.11 KND97863.1 - 0.23 12.0 7.1 1.4 9.5 1.0 2.7 2 0 0 2 2 2 0 MerR, DNA binding TPR_MLP1_2 PF07926.12 KND97863.1 - 0.4 10.7 28.1 0.68 10.0 3.6 3.0 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein AAA_23 PF13476.6 KND97863.1 - 0.76 10.3 17.9 0.68 10.4 15.2 2.3 2 0 0 2 2 2 0 AAA domain Syntaxin-6_N PF09177.11 KND97863.1 - 1.6 9.3 13.4 4.6 7.9 1.9 2.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF4200 PF13863.6 KND97863.1 - 2 8.8 32.8 9.3 6.7 11.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) HrpB7 PF09486.10 KND97863.1 - 2.3 8.6 16.1 3.9 7.9 2.8 2.7 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) COG2 PF06148.11 KND97863.1 - 2.4 8.3 17.0 1.4 9.0 2.4 3.1 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF724 PF05266.14 KND97863.1 - 2.6 7.8 25.4 0.88 9.4 11.2 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF724) CC2-LZ PF16516.5 KND97863.1 - 3.7 8.0 23.0 0.17 12.3 2.7 3.0 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF1664 PF07889.12 KND97863.1 - 3.9 7.5 14.2 3.2 7.8 3.0 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4160 PF13711.6 KND97863.1 - 4 7.8 8.3 39 4.7 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4160) Atg14 PF10186.9 KND97863.1 - 4.1 6.4 24.4 7.9 5.5 9.4 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAM76 PF16046.5 KND97863.1 - 4.4 6.6 14.4 8.8 5.6 14.4 1.6 1 0 0 1 1 1 0 FAM76 protein DUF1515 PF07439.11 KND97863.1 - 5.6 7.0 7.9 1.7 8.7 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Sec8_exocyst PF04048.14 KND97863.1 - 9.2 6.1 14.0 1.9 8.4 0.5 3.7 2 1 2 4 4 4 0 Sec8 exocyst complex component specific domain WD40 PF00400.32 KND97865.1 - 1.3e-34 117.6 19.1 6.8e-08 33.1 0.5 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND97865.1 - 6.7e-14 52.0 0.3 0.045 14.0 0.0 5.6 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 KND97865.1 - 1.1e-10 40.9 3.1 1.8e-10 40.2 3.1 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Ge1_WD40 PF16529.5 KND97865.1 - 3e-07 29.7 0.0 1.3 7.9 0.0 5.4 2 1 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KND97865.1 - 1.3e-05 25.2 0.0 0.021 14.7 0.0 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KND97865.1 - 0.012 14.9 0.0 18 4.6 0.0 3.6 3 1 0 3 3 3 0 WD40-like domain Nbas_N PF15492.6 KND97865.1 - 0.09 12.1 0.5 19 4.5 0.0 3.2 3 1 2 5 5 5 0 Neuroblastoma-amplified sequence, N terminal DHFR_2 PF06442.11 KND97865.1 - 0.098 12.5 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 R67 dihydrofolate reductase DUF1373 PF07117.11 KND97865.1 - 0.52 10.3 1.3 1.6 8.7 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1373) DUF4695 PF15766.5 KND97865.1 - 0.89 9.8 5.9 0.11 12.8 1.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4695) 2OG-FeII_Oxy PF03171.20 KND97866.1 - 6.1e-05 23.5 0.0 0.00033 21.1 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF713 PF05218.14 KND97866.1 - 0.014 15.1 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF713) Peptidase_M16 PF00675.20 KND97867.1 - 3.5e-30 104.9 0.0 7.3e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KND97867.1 - 3.6e-12 46.7 0.3 1.6e-06 28.3 0.0 3.5 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16_M PF16187.5 KND97867.1 - 4.4e-11 42.6 0.0 1.4e-10 41.0 0.0 1.8 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M44 PF03410.13 KND97867.1 - 0.028 13.0 0.0 0.053 12.1 0.0 1.4 1 0 0 1 1 1 0 Metallopeptidase from vaccinia pox Cu_amine_oxid PF01179.20 KND97869.1 - 6e-152 506.3 0.2 7.3e-152 506.0 0.2 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Peptidase_M99 PF17033.5 KND97869.1 - 0.043 13.3 0.1 0.07 12.6 0.1 1.2 1 0 0 1 1 1 0 Carboxypeptidase controlling helical cell shape catalytic LRR_8 PF13855.6 KND97870.1 - 3e-15 55.7 19.2 2e-10 40.3 1.3 4.0 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 KND97870.1 - 5e-13 49.0 26.0 3.3e-07 30.5 5.1 4.8 3 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KND97870.1 - 0.00073 19.1 5.0 0.00073 19.1 5.0 2.6 3 1 1 4 4 4 1 Leucine-rich repeat LRR_5 PF13306.6 KND97870.1 - 0.0028 17.6 0.8 0.0028 17.6 0.8 2.5 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KND97870.1 - 0.62 10.3 15.0 0.94 9.7 1.0 4.6 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 KND97870.1 - 6.9 7.6 18.8 36 5.5 0.1 5.7 3 1 1 4 4 4 0 Leucine Rich Repeat Glyco_hydro_3_C PF01915.22 KND97871.1 - 1.7e-41 142.5 0.0 2.5e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KND97871.1 - 2e-36 126.0 0.0 4.5e-36 124.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KND97871.1 - 3.7e-21 75.0 0.0 7.6e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain YtxH PF12732.7 KND97872.1 - 2.7 8.6 6.5 40 4.8 0.2 3.5 2 1 0 2 2 2 0 YtxH-like protein DNA_pol_E_B PF04042.16 KND97873.1 - 3.6e-41 140.8 0.1 5.3e-41 140.3 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Prenyltrans PF00432.21 KND97874.1 - 2.7e-56 187.0 1.2 7e-12 44.9 0.0 5.2 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KND97874.1 - 2.4e-05 23.6 0.0 0.047 12.8 0.0 3.6 2 1 3 5 5 5 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KND97874.1 - 0.032 13.3 0.0 0.27 10.3 0.0 2.3 1 1 1 2 2 2 0 Squalene-hopene cyclase C-terminal domain Mannosyl_trans3 PF11051.8 KND97875.1 - 4e-77 259.3 2.8 4e-77 259.3 2.8 1.8 2 0 0 2 2 2 1 Mannosyltransferase putative Glyco_transf_8 PF01501.20 KND97875.1 - 0.00036 20.2 3.8 0.0042 16.7 0.4 2.7 1 1 0 2 2 2 2 Glycosyl transferase family 8 Aldolase_II PF00596.21 KND97876.1 - 6.7e-41 140.3 0.0 8.7e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain AA_permease PF00324.21 KND97877.1 - 1.3e-143 479.1 43.4 1.6e-143 478.8 43.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND97877.1 - 1.4e-42 146.0 45.6 2e-42 145.6 45.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 KND97877.1 - 0.0054 15.6 2.1 0.021 13.6 0.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4781) AA_permease PF00324.21 KND97878.1 - 1.1e-142 476.1 36.5 1.2e-142 475.9 36.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND97878.1 - 5.3e-43 147.4 39.5 6.8e-43 147.1 39.5 1.1 1 0 0 1 1 1 1 Amino acid permease Nop PF01798.18 KND97880.1 - 1.1e-84 283.5 0.2 1.1e-84 283.5 0.2 2.2 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KND97880.1 - 4.3e-19 68.7 2.9 4.3e-19 68.7 2.9 2.8 2 1 0 2 2 2 1 NOP5NT (NUC127) domain Dna2 PF08696.11 KND97881.1 - 4.2e-54 183.5 0.0 1.4e-53 181.7 0.0 1.9 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.6 KND97881.1 - 2.5e-50 170.9 0.0 6.2e-50 169.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KND97881.1 - 3.9e-28 99.0 0.1 2e-13 50.7 0.0 3.1 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 KND97881.1 - 4e-12 46.2 0.0 8.5e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KND97881.1 - 1e-10 42.1 0.0 2.4e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KND97881.1 - 4.2e-06 26.7 2.0 1.4 8.6 0.0 4.2 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase Cas_Cas4 PF01930.17 KND97881.1 - 4.4e-06 26.9 0.0 8.1e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF83 UvrD-helicase PF00580.21 KND97881.1 - 3.7e-05 23.4 0.7 0.00015 21.4 0.0 2.3 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_18 PF13238.6 KND97881.1 - 0.0058 17.2 0.1 0.094 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KND97881.1 - 0.01 15.5 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SH3_2 PF07653.17 KND97881.1 - 0.04 13.6 0.0 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 Variant SH3 domain ResIII PF04851.15 KND97881.1 - 0.087 12.8 0.1 0.25 11.4 0.1 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_5 PF07728.14 KND97881.1 - 0.088 12.8 0.1 0.26 11.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KND97881.1 - 0.11 12.9 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Helicase_RecD PF05127.14 KND97881.1 - 0.13 12.1 0.0 0.42 10.4 0.0 1.9 1 1 0 1 1 1 0 Helicase DUF87 PF01935.17 KND97881.1 - 0.16 12.0 1.3 0.6 10.2 0.4 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Sel1 PF08238.12 KND97882.1 - 3.3e-24 84.8 13.8 0.0015 19.2 0.1 7.9 7 0 0 7 7 7 6 Sel1 repeat TPR_16 PF13432.6 KND97882.1 - 0.0054 17.3 1.8 0.053 14.2 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KND97882.1 - 0.025 14.9 1.4 35 4.8 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 KND97882.1 - 0.052 13.6 0.1 6.5 6.9 0.0 3.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 KND97882.1 - 0.13 12.2 0.2 0.13 12.2 0.2 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Sec61_beta PF03911.16 KND97882.1 - 0.5 10.4 3.4 0.9 9.6 3.4 1.4 1 0 0 1 1 1 0 Sec61beta family TPR_8 PF13181.6 KND97882.1 - 2.6 8.5 8.4 15 6.1 0.0 5.6 4 1 1 5 5 5 0 Tetratricopeptide repeat V_ATPase_I PF01496.19 KND97883.1 - 2.4e-285 948.6 13.0 7.1e-218 725.5 14.0 2.0 2 0 0 2 2 2 2 V-type ATPase 116kDa subunit family DUF5082 PF16888.5 KND97883.1 - 2.8 8.3 5.6 18 5.6 0.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) TetR_C_8 PF14278.6 KND97884.1 - 0.1 12.7 0.0 0.13 12.4 0.0 1.3 1 1 0 1 1 1 0 Transcriptional regulator C-terminal region NDC10_II PF16787.5 KND97885.1 - 9.6e-20 70.9 9.6 9e-18 64.4 9.6 2.3 1 1 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 SurE PF01975.17 KND97889.1 - 5.1e-41 140.6 0.0 7e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Peroxin-3 PF04882.12 KND97890.1 - 2.9e-95 320.0 16.1 9.2e-92 308.5 16.1 2.6 1 1 0 1 1 1 1 Peroxin-3 XPC-binding PF09280.11 KND97890.1 - 0.058 13.1 0.6 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 XPC-binding domain Skp1 PF01466.19 KND97891.1 - 2.7e-24 85.0 0.3 5.4e-24 84.1 0.3 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KND97891.1 - 6.7e-21 74.2 1.1 1.8e-20 72.8 1.1 1.8 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Sds3 PF08598.11 KND97892.1 - 0.0061 16.6 10.3 0.014 15.4 10.0 1.7 1 1 0 1 1 1 1 Sds3-like Thioredoxin_7 PF13899.6 KND97893.1 - 3e-23 81.8 0.0 6.7e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 KND97893.1 - 2.9e-10 39.8 0.4 5.4e-10 38.9 0.4 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KND97893.1 - 2.3e-09 37.3 0.0 4.5e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin_2 PF13098.6 KND97893.1 - 0.0063 17.0 0.0 0.019 15.4 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredox_DsbH PF03190.15 KND97893.1 - 0.016 15.1 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Lipocalin_5 PF13924.6 KND97893.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Lipocalin-like domain Pkinase PF00069.25 KND97895.1 - 3.4e-46 157.8 0.2 2e-44 151.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND97895.1 - 1.1e-23 83.8 0.0 3.3e-23 82.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KND97895.1 - 0.00013 21.0 0.1 0.0002 20.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KND97895.1 - 0.02 14.8 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Fungal_trans PF04082.18 KND97896.1 - 3.9e-11 42.5 0.7 6.2e-11 41.8 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1479 PF07350.12 KND97897.1 - 2.5e-149 497.6 0.0 3.4e-149 497.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 KND97897.1 - 0.0013 19.0 0.2 0.037 14.3 0.2 2.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Epimerase PF01370.21 KND97898.1 - 1.4e-18 67.3 0.0 2e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KND97898.1 - 2.3e-15 56.4 0.0 3.1e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KND97898.1 - 1.1e-11 44.4 0.1 8.3e-06 25.2 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KND97898.1 - 3.9e-09 36.4 0.0 5.9e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KND97898.1 - 8.6e-09 35.5 0.0 1.4e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KND97898.1 - 0.00011 21.5 0.1 0.00024 20.3 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KND97898.1 - 0.00077 19.1 0.1 0.0019 17.8 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 KND97898.1 - 0.0056 16.2 0.0 0.011 15.2 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND97898.1 - 0.0078 16.1 0.0 0.02 14.8 0.0 1.6 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KND97898.1 - 0.0094 16.5 0.0 0.033 14.8 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 KND97898.1 - 0.069 12.2 0.1 0.26 10.3 0.1 2.0 1 1 0 1 1 1 0 RmlD substrate binding domain Circo_capsid PF02443.15 KND97898.1 - 0.081 12.5 0.2 0.12 12.0 0.2 1.1 1 0 0 1 1 1 0 Circovirus capsid protein Semialdhyde_dh PF01118.24 KND97898.1 - 0.11 13.0 0.1 0.46 10.9 0.0 2.1 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain WD40 PF00400.32 KND97899.1 - 1.1e-14 54.6 22.7 0.00014 22.6 0.0 10.8 12 1 0 12 12 12 4 WD domain, G-beta repeat CPSF_A PF03178.15 KND97899.1 - 5.5e-07 29.2 0.1 0.00095 18.6 0.0 2.5 2 0 0 2 2 2 2 CPSF A subunit region WD40_like PF17005.5 KND97899.1 - 0.016 14.6 5.5 0.96 8.7 0.2 4.3 3 1 1 4 4 4 0 WD40-like domain Hira PF07569.11 KND97899.1 - 0.023 14.4 0.0 10 5.8 0.0 3.2 3 0 0 3 3 3 0 TUP1-like enhancer of split tRNA-synt_1 PF00133.22 KND97900.1 - 1.7e-232 773.0 0.7 3.2e-232 772.1 0.2 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KND97900.1 - 2.5e-26 92.5 0.0 5.8e-26 91.3 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KND97900.1 - 1.5e-15 56.8 1.3 1.2e-05 24.3 0.1 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KND97900.1 - 0.0019 17.7 0.3 0.081 12.4 0.1 2.4 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KND97900.1 - 0.0055 16.1 0.0 0.04 13.3 0.0 2.3 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain ATP_bind_3 PF01171.20 KND97901.1 - 6.7e-46 156.3 0.0 1.1e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 PP-loop family Asn_synthase PF00733.21 KND97901.1 - 0.00032 20.5 0.0 0.00059 19.6 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.16 KND97901.1 - 0.042 12.6 0.0 0.07 11.9 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase Peptidase_M1_N PF17900.1 KND97902.1 - 0.0029 17.8 0.5 2.7 8.1 0.1 2.8 2 1 0 2 2 2 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 KND97902.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.7 1 1 0 1 1 1 0 Peptidase family M1 domain Ntox28 PF15605.6 KND97902.1 - 0.13 12.5 0.9 4.3 7.6 0.0 3.1 3 0 0 3 3 3 0 Bacterial toxin 28 VPS9 PF02204.18 KND97903.1 - 2.6e-31 107.9 0.4 5e-31 107.0 0.4 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KND97903.1 - 3.4e-09 36.9 2.9 1.1e-08 35.3 0.1 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF5601) CUE PF02845.16 KND97903.1 - 1.4e-05 24.7 0.7 5.1e-05 22.9 0.1 2.3 2 0 0 2 2 2 1 CUE domain CBM46 PF18448.1 KND97903.1 - 0.076 13.3 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Carbohydrate binding domain EutQ PF06249.12 KND97904.1 - 4.9e-09 36.1 0.0 5.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 KND97904.1 - 1.8e-08 34.0 0.1 2.5e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 KND97904.1 - 1.3e-06 28.0 0.1 1.8e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KND97904.1 - 0.0025 17.4 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.7 KND97904.1 - 0.019 14.7 0.0 0.03 14.0 0.0 1.3 1 1 0 1 1 1 0 Cupin Pirin PF02678.16 KND97904.1 - 0.028 14.4 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Pirin ARD PF03079.14 KND97904.1 - 0.11 12.6 0.1 0.16 12.2 0.1 1.2 1 0 0 1 1 1 0 ARD/ARD' family CDC37_N PF03234.14 KND97905.1 - 5.1e-44 150.3 5.4 5.1e-44 150.3 5.4 3.4 3 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KND97905.1 - 5.2e-40 136.1 2.7 7.9e-40 135.5 1.4 2.0 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KND97905.1 - 7.4e-19 67.7 3.1 7.4e-19 67.7 3.1 2.7 3 1 0 3 3 3 1 Cdc37 C terminal domain AAA_6 PF12774.7 KND97905.1 - 0.032 13.2 0.4 0.067 12.1 0.4 1.5 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region RRM_1 PF00076.22 KND97906.1 - 2.2e-10 40.2 0.0 4.2e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KND97906.1 - 7.6e-05 22.3 0.0 0.00035 20.2 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vma12 PF11712.8 KND97906.1 - 0.47 10.5 2.9 7.9 6.6 3.2 2.6 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase GFO_IDH_MocA PF01408.22 KND97907.1 - 2.8e-21 76.6 0.1 1.4e-20 74.3 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KND97907.1 - 3.5e-05 23.8 0.0 8.3e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sec20 PF03908.13 KND97908.1 - 4.1e-26 90.7 1.8 4.1e-26 90.7 1.8 3.7 3 2 1 4 4 4 1 Sec20 FOXP-CC PF16159.5 KND97908.1 - 2.8 8.7 6.7 0.4 11.3 0.5 2.8 2 1 0 2 2 2 0 FOXP coiled-coil domain Exo_endo_phos PF03372.23 KND97909.1 - 1.2e-26 93.7 0.1 1.7e-26 93.2 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Mob1_phocein PF03637.17 KND97910.1 - 4.3e-73 244.9 0.4 5e-73 244.7 0.4 1.0 1 0 0 1 1 1 1 Mob1/phocein family Med5 PF08689.10 KND97910.1 - 0.027 12.3 0.0 0.041 11.7 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit Med5 ATG7_N PF16420.5 KND97912.1 - 0.076 12.6 0.1 0.094 12.3 0.1 1.1 1 0 0 1 1 1 0 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus RNA_polI_A34 PF08208.11 KND97916.1 - 0.071 13.2 0.2 0.12 12.4 0.2 1.4 1 1 1 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF4404 PF14357.6 KND97916.1 - 0.11 13.1 0.3 0.17 12.5 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Sod_Cu PF00080.20 KND97917.1 - 5e-15 55.9 0.0 8.6e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Fe-S_biosyn PF01521.20 KND97918.1 - 3.6e-19 69.0 0.0 5.5e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis LPD38 PF18857.1 KND97918.1 - 0.0052 17.0 0.7 0.0077 16.4 0.7 1.2 1 0 0 1 1 1 1 Large polyvalent protein associated domain 38 Ndc1_Nup PF09531.10 KND97918.1 - 0.062 12.0 5.4 0.065 11.9 5.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mitofilin PF09731.9 KND97918.1 - 0.46 9.3 10.2 0.56 9.0 10.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Presenilin PF01080.17 KND97918.1 - 1.6 7.4 3.7 1.7 7.3 3.7 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_S30 PF01577.16 KND97918.1 - 4.3 6.9 8.7 7.7 6.0 8.5 1.5 2 0 0 2 2 2 0 Potyvirus P1 protease GREB1 PF15782.5 KND97918.1 - 8 3.4 7.4 9.2 3.2 7.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2981 PF11200.8 KND97918.1 - 9.6 5.8 7.1 12 5.5 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Creatinase_N_2 PF16189.5 KND97919.1 - 2.7e-50 170.6 0.8 5.9e-50 169.5 0.8 1.6 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KND97919.1 - 8.7e-36 123.6 0.0 1.2e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KND97919.1 - 1.6e-20 72.9 2.1 4.4e-20 71.5 1.1 2.4 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KND97919.1 - 3.1e-11 44.0 0.0 2.2e-07 31.6 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Importin_rep PF18773.1 KND97922.1 - 0.16 11.7 1.1 4.2 7.2 0.0 2.5 2 0 0 2 2 2 0 Importin 13 repeat DUF577 PF04510.12 KND97922.1 - 0.18 11.7 2.6 11 5.9 0.0 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF577) Rep_fac-A_C PF08646.10 KND97923.1 - 1.2e-53 180.8 6.4 2.1e-51 173.5 1.5 3.2 4 0 0 4 4 4 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KND97923.1 - 1.7e-35 120.9 4.5 5.6e-33 112.8 0.4 3.5 4 0 0 4 4 4 2 Replication protein A OB domain tRNA_anti-codon PF01336.25 KND97923.1 - 7.4e-16 57.9 0.2 1.5e-09 37.7 0.0 4.1 4 1 0 4 4 4 3 OB-fold nucleic acid binding domain Rep-A_N PF04057.12 KND97923.1 - 1.5e-11 44.2 0.0 5.7e-11 42.3 0.0 1.9 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain CDC24_OB3 PF17244.2 KND97923.1 - 6.2e-07 29.4 0.0 7.1e-06 25.9 0.0 2.2 1 1 0 1 1 1 1 Cell division control protein 24, OB domain 3 TPP1 PF10341.9 KND97923.1 - 0.047 13.7 0.4 0.19 11.7 0.2 2.2 2 0 0 2 2 2 0 Shelterin complex subunit, TPP1/ACD Cys_Met_Meta_PP PF01053.20 KND97924.1 - 3.6e-134 447.1 0.0 4.2e-134 446.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KND97924.1 - 4.3e-06 26.3 0.0 0.00012 21.5 0.0 2.6 2 1 1 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KND97924.1 - 3.8e-05 23.0 0.0 6.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KND97924.1 - 0.0044 16.0 0.1 0.011 14.7 0.1 1.6 1 1 0 1 1 1 1 Aminotransferase class-V 2Fe-2S_thioredx PF01257.19 KND97925.1 - 6.6e-61 204.4 0.3 8.1e-61 204.1 0.3 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Transp_cyt_pur PF02133.15 KND97926.1 - 2e-52 178.4 28.8 2.5e-52 178.1 28.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4149 PF13664.6 KND97926.1 - 4.3 7.7 11.1 0.16 12.3 1.7 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4149) ELP6 PF09807.9 KND97927.1 - 0.00012 21.6 0.0 0.00041 19.9 0.0 1.7 1 1 0 1 1 1 1 Elongation complex protein 6 TrbI_Ftype PF09677.10 KND97927.1 - 0.0098 16.2 0.0 0.025 14.9 0.0 1.6 1 0 0 1 1 1 1 Type-F conjugative transfer system protein (TrbI_Ftype) DUF3336 PF11815.8 KND97928.1 - 2e-33 115.1 4.5 3.3e-33 114.3 4.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KND97928.1 - 2.5e-05 24.5 2.1 6.7e-05 23.2 2.1 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase DUF4386 PF14329.6 KND97928.1 - 0.041 13.8 0.1 0.082 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) MFS_1 PF07690.16 KND97929.1 - 1.7e-25 89.7 34.4 1.4e-15 57.1 13.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KND97929.1 - 0.00029 19.8 21.2 0.0086 15.0 7.5 2.1 2 0 0 2 2 2 2 MFS_1 like family ATG22 PF11700.8 KND97929.1 - 0.57 8.7 21.1 0.15 10.7 10.8 3.6 3 1 0 3 3 3 0 Vacuole effluxer Atg22 like MFS_3 PF05977.13 KND97929.1 - 5 5.4 10.4 0.036 12.5 0.8 1.9 2 0 0 2 2 2 0 Transmembrane secretion effector UTP15_C PF09384.10 KND97930.1 - 2.7e-43 147.2 0.0 4.3e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KND97930.1 - 1.4e-08 35.2 8.6 0.061 14.2 0.1 6.4 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND97930.1 - 0.0011 19.2 0.0 7.6 6.9 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain TBPIP PF07106.13 KND97930.1 - 0.065 13.2 0.0 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain PHD PF00628.29 KND97931.1 - 0.00012 21.9 6.3 0.00027 20.8 6.3 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KND97931.1 - 0.002 18.3 1.6 0.0051 17.0 1.6 1.8 1 1 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KND97931.1 - 0.1 12.8 2.1 0.22 11.7 1.9 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain AT_hook PF02178.19 KND97931.1 - 1.7 8.8 9.4 0.08 12.9 2.1 2.6 2 0 0 2 2 2 0 AT hook motif DUF2829 PF11195.8 KND97931.1 - 1.8 8.9 5.1 2.1 8.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2829) Ribosomal_L3 PF00297.22 KND97932.1 - 1.3e-185 616.7 12.3 1.4e-185 616.5 12.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 IL6Ra-bind PF09240.10 KND97933.1 - 0.026 14.9 1.0 0.053 14.0 0.5 1.7 1 1 0 1 1 1 0 Interleukin-6 receptor alpha chain, binding NAD_binding_10 PF13460.6 KND97934.1 - 0.00042 20.3 0.2 0.00083 19.3 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KND97934.1 - 0.00073 18.6 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KND97934.1 - 0.025 14.1 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KND97934.1 - 0.074 13.3 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain MalF_P2 PF14785.6 KND97935.1 - 0.034 14.2 1.4 0.17 11.9 0.1 2.4 3 0 0 3 3 3 0 Maltose transport system permease protein MalF P2 domain AT_hook PF02178.19 KND97935.1 - 0.085 12.8 5.6 0.29 11.1 5.6 2.0 1 0 0 1 1 1 0 AT hook motif ERG4_ERG24 PF01222.17 KND97936.1 - 8.3e-148 492.7 13.5 9.4e-148 492.5 13.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KND97936.1 - 2.2e-08 33.9 2.4 2.2e-08 33.9 2.4 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1295) ATP-synt_S1 PF05827.12 KND97937.1 - 7e-06 25.9 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) VMA21 PF09446.10 KND97938.1 - 3.3e-07 30.3 10.5 8.7e-07 29.0 10.5 1.6 1 1 0 1 1 1 1 VMA21-like domain Med18 PF09637.10 KND97939.1 - 1e-83 281.0 1.7 1.2e-83 280.8 1.7 1.0 1 0 0 1 1 1 1 Med18 protein DUF5605 PF18310.1 KND97939.1 - 0.12 12.2 0.0 0.85 9.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5605) DUF5452 PF17533.2 KND97940.1 - 0.00089 19.4 0.5 0.0015 18.7 0.1 1.5 2 0 0 2 2 2 1 Family of unknown function (DUF5452) Pescadillo_N PF06732.11 KND97941.1 - 5.5e-120 400.0 0.5 5.5e-120 400.0 0.5 1.9 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 KND97941.1 - 1.5e-08 34.9 0.0 9.1e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KND97941.1 - 0.13 12.6 0.0 0.66 10.3 0.0 2.3 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain Acyltransferase PF01553.21 KND97942.1 - 1.3e-10 41.0 0.0 9.1e-10 38.3 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase PPR PF01535.20 KND97943.1 - 0.022 15.0 0.8 68 4.1 0.0 4.9 5 0 0 5 5 5 0 PPR repeat PPR_2 PF13041.6 KND97943.1 - 0.035 14.3 1.2 39 4.5 0.0 4.8 5 1 0 5 5 5 0 PPR repeat family Kinesin PF00225.23 KND97944.1 - 9.9e-98 327.1 3.2 9.9e-98 327.1 3.2 2.4 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KND97944.1 - 1.4e-44 151.7 0.1 1.4e-44 151.7 0.1 3.2 2 1 1 3 3 3 1 Microtubule binding YhzD PF14120.6 KND97944.1 - 0.064 13.4 0.2 0.44 10.7 0.1 2.5 2 0 0 2 2 2 0 YhzD-like protein AAA_24 PF13479.6 KND97944.1 - 0.44 10.2 4.7 4 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain Rrp15p PF07890.12 KND97945.1 - 4.5e-32 111.2 13.1 4.5e-32 111.2 13.1 2.2 2 1 0 2 2 2 1 Rrp15p DUF3333 PF11812.8 KND97945.1 - 0.11 12.7 2.0 0.55 10.4 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) DHHW PF14286.6 KND97945.1 - 0.57 9.5 4.4 0.83 8.9 4.4 1.2 1 0 0 1 1 1 0 DHHW protein CDC45 PF02724.14 KND97945.1 - 0.99 7.6 13.3 1.1 7.4 13.3 1.2 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.16 KND97946.1 - 4.7e-29 101.4 24.4 9.3e-24 84.0 12.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KND97946.1 - 0.0013 17.6 5.4 0.0013 17.6 5.4 2.3 1 1 1 2 2 2 2 MFS_1 like family LapD_MoxY_N PF16448.5 KND97946.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 LapD/MoxY periplasmic domain SGS PF05002.15 KND97947.1 - 4.8e-28 97.1 1.4 1.3e-27 95.7 1.4 1.8 1 0 0 1 1 1 1 SGS domain CS PF04969.16 KND97947.1 - 5e-19 69.1 1.0 1.2e-18 67.9 1.0 1.6 1 0 0 1 1 1 1 CS domain TPR_16 PF13432.6 KND97947.1 - 1.9e-05 25.2 0.7 0.00018 22.1 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KND97947.1 - 6.3e-05 22.8 9.9 0.44 10.8 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KND97947.1 - 0.00045 19.9 11.7 0.9 9.5 0.9 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KND97947.1 - 0.0081 16.4 0.6 0.0081 16.4 0.6 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KND97947.1 - 0.015 15.4 7.8 0.55 10.6 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KND97947.1 - 0.025 15.1 2.2 0.39 11.2 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KND97947.1 - 0.16 11.7 5.9 0.24 11.1 0.5 2.4 2 0 0 2 2 2 0 TPR repeat SRP9-21 PF05486.12 KND97950.1 - 2.5e-18 66.3 0.6 2.5e-18 66.3 0.6 2.0 1 1 1 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) DNA_pol3_delta PF06144.13 KND97950.1 - 0.024 14.4 1.4 0.037 13.8 1.4 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Nramp PF01566.18 KND97952.1 - 3.2e-87 292.8 14.7 9.6e-52 176.1 5.0 2.9 3 0 0 3 3 3 2 Natural resistance-associated macrophage protein Biotin_lipoyl PF00364.22 KND97953.1 - 1.3e-19 69.7 0.9 2.4e-19 68.9 0.9 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KND97953.1 - 4.6e-08 33.3 0.5 1.5e-07 31.6 0.1 2.1 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KND97953.1 - 0.08 12.8 0.2 0.54 10.1 0.0 2.3 2 0 0 2 2 2 0 Biotin-lipoyl like AT_hook PF02178.19 KND97954.1 - 0.0033 17.1 21.9 0.011 15.5 0.8 3.5 3 0 0 3 3 3 3 AT hook motif TFIIIC_delta PF12657.7 KND97957.1 - 4.1e-13 49.7 0.1 3.5e-12 46.6 0.0 2.4 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 KND97957.1 - 2.8e-05 24.0 0.0 0.00025 20.9 0.0 2.3 1 1 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex ANAPC4_WD40 PF12894.7 KND97957.1 - 0.085 13.2 0.0 0.35 11.2 0.0 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain NHL PF01436.21 KND97957.1 - 0.15 12.2 0.5 30 4.9 0.0 3.4 3 0 0 3 3 3 0 NHL repeat EI24 PF07264.11 KND97958.1 - 0.0062 16.8 9.6 0.17 12.1 9.6 2.6 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) PALP PF00291.25 KND97960.1 - 3e-60 204.1 0.2 3.7e-60 203.8 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme 2OG-FeII_Oxy_3 PF13640.6 KND97961.1 - 8.3e-09 36.2 0.1 1.4e-08 35.5 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SUB1_ProdP9 PF18213.1 KND97961.1 - 0.078 12.8 1.7 0.21 11.5 1.1 1.9 1 1 1 2 2 2 0 SUB1 protease Prodomain ProdP9 Nic96 PF04097.14 KND97962.1 - 2.9e-187 623.9 4.8 3.9e-187 623.5 4.8 1.2 1 0 0 1 1 1 1 Nup93/Nic96 AA_permease_2 PF13520.6 KND97963.1 - 8.1e-50 169.9 53.7 1e-49 169.6 53.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KND97963.1 - 8.5e-17 60.9 46.4 1.1e-16 60.5 46.4 1.0 1 0 0 1 1 1 1 Amino acid permease LNS2 PF08235.13 KND97964.1 - 1.2e-96 322.5 0.0 1.7e-96 322.1 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KND97964.1 - 1.2e-38 131.2 0.0 2.9e-38 129.9 0.0 1.7 1 0 0 1 1 1 1 lipin, N-terminal conserved region Hydrolase_6 PF13344.6 KND97964.1 - 0.0085 16.2 0.0 0.028 14.5 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase SDA1 PF05285.12 KND97964.1 - 3.1 7.1 29.6 5.9 6.2 29.6 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KND97964.1 - 3.9 5.6 32.7 0.12 10.6 26.8 1.3 2 0 0 2 2 2 0 Nop14-like family DUF3589 PF12141.8 KND97965.1 - 2e-166 554.4 0.0 2.4e-166 554.2 0.0 1.1 1 0 0 1 1 1 1 Beta-mannosyltransferases RRM_1 PF00076.22 KND97966.1 - 1.3e-21 76.2 0.1 3.3e-14 52.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KND97966.1 - 2.6e-06 27.4 0.2 0.0024 17.9 0.0 2.1 1 1 1 2 2 2 2 RNA binding motif RRM_occluded PF16842.5 KND97966.1 - 0.00027 20.7 0.0 0.016 15.0 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif BRAP2 PF07576.12 KND97966.1 - 0.0091 16.2 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 Calcipressin PF04847.12 KND97966.1 - 0.052 13.3 0.1 0.2 11.4 0.0 1.9 2 1 1 3 3 3 0 Calcipressin Limkain-b1 PF11608.8 KND97966.1 - 0.085 12.9 0.1 0.23 11.6 0.0 1.7 2 0 0 2 2 2 0 Limkain b1 Abhydrolase_3 PF07859.13 KND97967.1 - 2.9e-10 40.4 0.0 4.2e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KND97967.1 - 0.0023 16.8 0.0 0.0038 16.1 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 KND97967.1 - 0.0062 17.2 0.0 0.0091 16.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family AhpC-TSA PF00578.21 KND97967.1 - 0.013 15.5 0.0 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 AhpC/TSA family LIDHydrolase PF10230.9 KND97967.1 - 0.016 14.7 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 KND97967.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF915 PF06028.11 KND97967.1 - 0.031 13.6 0.0 0.12 11.7 0.0 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.8 KND97967.1 - 0.086 12.1 0.0 0.57 9.4 0.0 2.3 2 1 0 2 2 2 0 Serine aminopeptidase, S33 VirJ PF06057.11 KND97967.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) COesterase PF00135.28 KND97967.1 - 0.11 11.3 0.0 0.68 8.7 0.0 2.1 2 1 0 2 2 2 0 Carboxylesterase family eIF3g PF12353.8 KND97968.1 - 3.3e-43 147.1 3.1 4.5e-43 146.6 3.1 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KND97968.1 - 6.8e-15 54.6 0.0 1.1e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KND97968.1 - 0.015 14.8 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KND97969.1 - 2.6e-21 75.5 16.7 4.5e-07 30.5 0.0 7.0 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND97969.1 - 7e-07 29.5 0.1 1.5 9.1 0.0 4.8 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KND97969.1 - 0.014 13.9 0.2 0.82 8.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain STAG PF08514.11 KND97970.1 - 9.1e-30 102.9 2.6 2.8e-29 101.3 1.0 2.8 2 0 0 2 2 2 1 STAG domain DNA_pol3_a_NII PF11490.8 KND97970.1 - 0.075 12.9 2.4 0.37 10.7 2.4 2.2 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II SWIRM PF04433.17 KND97971.1 - 8.8e-29 99.7 1.6 3.1e-28 98.0 0.2 2.6 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.31 KND97971.1 - 1.3e-08 34.9 0.1 3.2e-08 33.6 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM-assoc_1 PF16495.5 KND97971.1 - 8.1e-06 25.7 8.2 2.5e-05 24.1 8.2 1.8 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-bind_6 PF13921.6 KND97971.1 - 0.00013 22.2 0.1 0.00013 22.2 0.1 3.5 4 0 0 4 4 4 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KND97971.1 - 0.012 16.0 0.1 0.049 14.0 0.1 2.1 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain PolyA_pol PF01743.20 KND97971.1 - 0.09 13.2 0.4 0.31 11.5 0.1 2.1 2 0 0 2 2 2 0 Poly A polymerase head domain GUN4 PF05419.12 KND97971.1 - 0.14 12.3 2.4 0.46 10.6 0.1 2.9 3 1 1 4 4 4 0 GUN4-like tRNA_Me_trans PF03054.16 KND97972.1 - 3.6e-117 391.1 0.0 4.1e-117 390.9 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 KND97972.1 - 8.8e-05 22.3 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.17 KND97972.1 - 0.0021 17.2 0.0 0.0097 15.0 0.0 1.9 2 0 0 2 2 2 1 NAD synthase ATP_bind_3 PF01171.20 KND97972.1 - 0.019 14.7 0.1 0.031 14.0 0.1 1.3 1 0 0 1 1 1 0 PP-loop family zf-C2H2 PF00096.26 KND97973.1 - 2.9e-08 33.7 15.4 1.4e-05 25.3 3.5 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KND97973.1 - 0.00011 22.1 1.1 0.00028 20.8 1.1 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KND97973.1 - 0.00036 20.8 2.1 0.00036 20.8 2.1 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KND97973.1 - 0.00079 20.1 1.8 0.00079 20.1 1.8 3.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KND97973.1 - 0.0091 16.3 4.6 0.024 14.9 2.5 2.5 2 0 0 2 2 2 1 C2H2-type zinc ribbon zf-met PF12874.7 KND97973.1 - 0.043 14.2 1.0 0.043 14.2 1.0 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FAM195 PF14799.6 KND97973.1 - 0.045 14.1 3.1 0.076 13.4 0.5 2.8 2 0 0 2 2 2 0 FAM195 family zf-C2H2_jaz PF12171.8 KND97973.1 - 0.069 13.5 0.3 0.3 11.4 0.3 2.2 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KND97973.1 - 0.21 12.2 0.3 0.21 12.2 0.3 3.9 3 1 1 4 4 4 0 FOXP coiled-coil domain LtrA PF06772.11 KND97974.1 - 4.9e-33 114.8 24.7 6.2e-33 114.5 24.7 1.0 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF4006 PF13179.6 KND97974.1 - 2.2 8.3 4.3 2 8.4 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF4006) AATase PF07247.12 KND97975.1 - 2.7e-51 174.7 1.1 4e-51 174.1 1.1 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 KND97975.1 - 0.0015 17.3 0.1 0.0027 16.5 0.1 1.3 1 0 0 1 1 1 1 Condensation domain DUF3481 PF11980.8 KND97977.1 - 0.0098 15.6 0.1 0.018 14.7 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of neuropilin glycoprotein CD99L2 PF12301.8 KND97977.1 - 0.041 14.2 1.8 0.041 14.2 1.8 1.8 1 1 1 2 2 2 0 CD99 antigen like protein 2 CAS_CSE1 PF03378.15 KND97978.1 - 0.18 10.3 2.8 0.19 10.2 2.8 1.0 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus LupA PF18242.1 KND97981.1 - 0.05 13.2 0.0 0.053 13.2 0.0 1.0 1 0 0 1 1 1 0 Legionella ubiquitin-specific protease A domain CENP-O PF09496.10 KND97983.1 - 2.2e-16 60.5 0.2 5e-16 59.3 0.2 1.5 1 1 0 1 1 1 1 Cenp-O kinetochore centromere component SlyX PF04102.12 KND97983.1 - 0.1 13.2 0.0 0.28 11.8 0.0 1.7 1 0 0 1 1 1 0 SlyX Clathrin PF00637.20 KND97984.1 - 9.7e-185 605.9 55.7 2.5e-31 108.5 0.2 7.8 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 KND97984.1 - 3.3e-27 94.2 0.7 3.3e-27 94.2 0.7 2.3 2 0 0 2 2 1 1 Clathrin-H-link Clathrin_propel PF01394.20 KND97984.1 - 1.5e-23 81.9 3.7 0.003 17.8 0.0 6.8 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin-link PF09268.10 KND97984.1 - 3.6e-07 29.4 0.0 1.1e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_2 PF07719.17 KND97984.1 - 5.3e-05 23.0 2.6 16 5.9 0.1 7.5 7 0 0 7 7 7 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 KND97984.1 - 0.00012 21.3 1.5 1.1 8.2 0.2 3.7 3 0 0 3 3 3 2 Coatomer WD associated region TPR_1 PF00515.28 KND97984.1 - 0.0011 18.6 11.5 10 6.1 0.1 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 KND97984.1 - 0.0036 17.5 2.4 30 5.0 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KND97984.1 - 0.013 15.5 6.4 69 3.8 0.0 7.1 8 0 0 8 8 6 0 Tetratricopeptide repeat PQQ_2 PF13360.6 KND97984.1 - 0.067 12.8 0.2 3.7 7.1 0.0 2.5 3 0 0 3 3 3 0 PQQ-like domain TPR_19 PF14559.6 KND97984.1 - 0.11 13.0 1.2 77 3.9 0.0 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat PPR PF01535.20 KND97984.1 - 0.15 12.4 4.2 69 4.0 0.0 5.8 6 0 0 6 6 5 0 PPR repeat TPR_17 PF13431.6 KND97984.1 - 1 9.9 4.1 6.3 7.4 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat PRP9_N PF16958.5 KND97984.1 - 1.1 9.3 4.6 0.32 11.0 0.4 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor PRP9 N-terminus Utp13 PF08625.11 KND97984.1 - 1.4 8.8 4.1 2.4 8.1 0.1 3.6 4 0 0 4 4 4 0 Utp13 specific WD40 associated domain Abhydrolase_1 PF00561.20 KND97987.1 - 1.1e-12 48.1 0.1 5e-12 46.0 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KND97987.1 - 4.8e-09 37.1 0.0 1.6e-08 35.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND97987.1 - 5.4e-08 32.4 0.0 7.1e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KND97987.1 - 1.1e-06 28.9 0.0 1.7e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KND97987.1 - 0.0024 17.7 0.5 0.07 12.8 0.5 2.1 1 1 0 1 1 1 1 PGAP1-like protein Ndr PF03096.14 KND97987.1 - 0.038 12.7 0.0 0.058 12.1 0.0 1.3 1 0 0 1 1 1 0 Ndr family DUF2920 PF11144.8 KND97987.1 - 0.049 12.8 0.0 0.069 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) ECH_2 PF16113.5 KND97987.1 - 0.13 11.7 0.1 10 5.5 0.0 2.1 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase CBFD_NFYB_HMF PF00808.23 KND97988.1 - 2.1e-13 50.3 3.4 3.5e-13 49.6 3.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KND97988.1 - 0.00022 21.3 0.1 0.00033 20.7 0.1 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KND97988.1 - 0.0074 16.7 0.1 0.0074 16.7 0.1 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KND97988.1 - 0.035 14.5 0.3 0.15 12.5 0.3 1.9 1 1 1 2 2 2 0 CENP-S protein NAD_Gly3P_dh_N PF01210.23 KND97988.1 - 0.087 12.8 0.8 0.15 12.0 0.8 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Bromo_TP PF07524.13 KND97988.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Orthopox_B11R PF07033.11 KND97988.1 - 0.64 9.8 6.1 0.1 12.4 1.5 2.1 2 2 0 2 2 2 0 Orthopoxvirus B11R protein Yos1 PF08571.10 KND97989.1 - 2.3e-32 111.1 0.8 2.6e-32 110.9 0.8 1.0 1 0 0 1 1 1 1 Yos1-like AXH PF08517.12 KND97989.1 - 0.034 14.7 0.0 0.045 14.3 0.0 1.1 1 0 0 1 1 1 0 Ataxin-1 and HBP1 module (AXH) TMEM191C PF15194.6 KND97989.1 - 0.096 12.9 0.7 0.14 12.4 0.2 1.5 2 0 0 2 2 2 0 TMEM191C family Cse1 PF08506.10 KND97990.1 - 2.4e-11 43.1 3.8 2.4e-11 43.1 3.8 4.0 2 2 1 3 3 3 1 Cse1 IBN_N PF03810.19 KND97990.1 - 2.4e-11 43.4 0.1 1.2e-10 41.2 0.1 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain HAUS-augmin3 PF14932.6 KND97990.1 - 0.0047 16.5 0.6 0.26 10.8 0.2 2.4 2 0 0 2 2 2 2 HAUS augmin-like complex subunit 3 UFD1 PF03152.14 KND97991.1 - 4e-71 238.0 0.0 5.1e-71 237.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Pribosyltran PF00156.27 KND97992.1 - 1e-08 34.9 0.2 2.6e-08 33.5 0.2 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DUF2141 PF09912.9 KND97992.1 - 0.018 14.9 0.3 0.03 14.2 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2141) Fe-ADH PF00465.19 KND97992.1 - 0.02 13.7 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase HSP70 PF00012.20 KND97994.1 - 7.1e-48 163.2 6.4 7.1e-48 163.2 6.4 2.9 1 1 2 3 3 3 1 Hsp70 protein RBM39linker PF15519.6 KND97994.1 - 0.32 12.1 4.0 3.3 8.8 2.7 2.9 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein OAD_gamma PF04277.13 KND97994.1 - 1.6 9.4 5.4 9.6 6.9 5.4 2.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain RRM_1 PF00076.22 KND97995.1 - 2.2e-11 43.4 0.0 0.0076 16.0 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KND97995.1 - 0.00071 19.4 0.0 0.55 10.1 0.0 2.7 2 0 0 2 2 2 2 Occluded RNA-recognition motif RabGAP-TBC PF00566.18 KND97996.1 - 8.2e-38 130.2 0.0 1.1e-37 129.8 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RRM_Rrp7 PF17799.1 KND97997.1 - 9.3e-51 171.8 0.0 2e-50 170.8 0.0 1.5 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRP7 PF12923.7 KND97997.1 - 3.1e-30 104.8 11.2 5.2e-30 104.0 11.2 1.4 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF45 PF01863.17 KND97997.1 - 0.89 9.6 4.7 1.4 9.0 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 Aminotran_4 PF01063.19 KND97998.1 - 2.2e-22 80.0 0.0 3.3e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Hydrolase PF00702.26 KND97999.1 - 1.3e-17 64.8 0.7 2.1e-17 64.1 0.2 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KND97999.1 - 3.5e-17 63.4 0.0 5.4e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KND97999.1 - 2.9e-12 46.9 0.5 1.5e-09 38.0 0.0 3.3 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KND97999.1 - 5.5e-05 23.3 2.9 0.24 11.5 0.0 3.0 3 1 0 3 3 3 2 Haloacid dehalogenase-like hydrolase S6PP PF05116.13 KND97999.1 - 0.043 13.3 2.3 0.53 9.8 0.0 2.8 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase CRAL_TRIO PF00650.20 KND98000.1 - 4e-36 124.1 0.0 6.3e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KND98000.1 - 1.2e-16 60.6 0.3 2.2e-16 59.8 0.3 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF1912 PF08930.10 KND98000.1 - 0.025 14.8 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) NNMT_PNMT_TEMT PF01234.17 KND98000.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family CENP-Q PF13094.6 KND98001.1 - 5.3e-15 56.0 7.8 5.3e-15 56.0 7.8 1.6 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Gam PF06064.11 KND98001.1 - 0.023 15.0 0.2 0.26 11.5 0.1 2.5 1 1 1 2 2 2 0 Host-nuclease inhibitor protein Gam DUF4420 PF14390.6 KND98001.1 - 0.031 13.5 1.1 0.21 10.8 0.3 2.2 2 0 0 2 2 2 0 Putative PD-(D/E)XK family member, (DUF4420) tRNA-synt_1d PF00750.19 KND98001.1 - 0.13 11.2 1.2 0.2 10.6 1.2 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (R) zf-RRN7 PF11781.8 KND98002.1 - 4.5e-07 29.4 0.7 4.5e-07 29.4 0.7 2.1 1 1 1 2 2 2 2 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Aldedh PF00171.22 KND98003.1 - 3.2e-179 596.3 0.5 3.7e-179 596.1 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KND98003.1 - 0.023 14.2 0.1 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) LuxC PF05893.14 KND98003.1 - 0.1 11.6 0.0 0.25 10.3 0.0 1.8 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Glucosaminidase PF01832.20 KND98003.1 - 0.14 12.7 0.0 0.81 10.2 0.0 2.3 2 0 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Ribosomal_S24e PF01282.19 KND98004.1 - 1.6e-35 120.9 0.0 2.8e-35 120.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e IPK PF03770.16 KND98005.1 - 2.3e-46 158.1 0.0 3.4e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase FAM194 PF14977.6 KND98006.1 - 0.11 11.8 2.2 0.19 11.0 2.2 1.4 1 1 0 1 1 1 0 FAM194 protein Glyco_transf_15 PF01793.16 KND98007.1 - 4.4e-104 348.3 3.2 5.3e-104 348.0 3.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Mannosyl_trans3 PF11051.8 KND98008.1 - 1.8e-78 263.7 0.0 2.9e-78 263.0 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Clat_adaptor_s PF01217.20 KND98010.1 - 1.9e-51 173.8 1.7 2.2e-51 173.5 1.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RexB PF15968.5 KND98010.1 - 0.09 13.2 0.1 0.12 12.8 0.1 1.2 1 0 0 1 1 1 0 Membrane-anchored ion channel, Abi component DEAD PF00270.29 KND98011.1 - 6.7e-51 172.5 0.0 1.8e-50 171.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND98011.1 - 2.4e-24 85.8 0.3 9.2e-23 80.7 0.0 3.4 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KND98011.1 - 7.7e-17 61.3 7.4 7.7e-17 61.3 7.4 3.2 3 1 0 3 3 3 1 DBP10CT (NUC160) domain ERCC3_RAD25_C PF16203.5 KND98011.1 - 0.061 12.5 1.5 0.074 12.2 0.0 1.9 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase RRM_1 PF00076.22 KND98012.1 - 2e-33 114.0 0.0 9.6e-16 57.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KND98012.1 - 2.4e-11 43.6 0.1 4.6e-06 26.7 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif RL PF17797.1 KND98012.1 - 0.048 13.6 0.0 11 6.0 0.0 2.4 2 0 0 2 2 2 0 RL domain TFIIA PF03153.13 KND98012.1 - 4.6 7.1 44.4 2.6 7.9 16.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit UPF0020 PF01170.18 KND98014.1 - 3e-11 43.4 0.0 9.7e-10 38.4 0.0 2.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 KND98014.1 - 0.0039 16.5 0.2 0.018 14.3 0.0 2.2 2 1 0 2 2 2 1 N-6 DNA Methylase N6_N4_Mtase PF01555.18 KND98014.1 - 0.013 15.2 0.1 0.86 9.3 0.0 2.5 2 1 0 2 2 2 0 DNA methylase Thi4 PF01946.17 KND98015.1 - 2.4e-114 380.4 0.0 2.9e-114 380.2 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KND98015.1 - 4.6e-07 29.8 1.7 2.6e-06 27.3 0.8 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KND98015.1 - 5.7e-07 29.7 0.1 3.2e-06 27.3 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KND98015.1 - 1.2e-06 27.9 2.3 7.5e-05 22.0 1.1 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KND98015.1 - 4.8e-06 25.9 0.6 1.2e-05 24.6 0.5 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KND98015.1 - 5.2e-06 25.9 0.0 6.1e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KND98015.1 - 0.00055 20.0 0.8 0.0018 18.3 0.0 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KND98015.1 - 0.001 18.5 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KND98015.1 - 0.0023 16.7 0.4 0.0039 16.0 0.4 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 KND98015.1 - 0.0039 16.3 0.5 0.007 15.5 0.3 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KND98015.1 - 0.0075 15.5 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KND98015.1 - 0.016 14.4 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KND98015.1 - 0.089 11.6 0.2 0.13 11.1 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase CPSF73-100_C PF11718.8 KND98016.1 - 1.9e-62 210.6 8.9 3.1e-62 210.0 8.9 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KND98016.1 - 9e-33 112.9 0.1 3.5e-32 111.0 0.0 2.1 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.27 KND98016.1 - 1.1e-19 71.3 0.4 2.1e-19 70.3 0.4 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KND98016.1 - 7.9e-18 64.6 0.0 2.1e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KND98016.1 - 4.3e-13 49.0 0.0 9.2e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_3 PF13483.6 KND98016.1 - 5.1e-06 26.5 0.0 4.9e-05 23.3 0.0 2.5 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KND98016.1 - 3.4e-05 23.5 0.5 0.00028 20.5 0.3 2.4 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KND98016.1 - 0.0018 17.5 0.0 0.0043 16.3 0.0 1.6 1 0 0 1 1 1 1 Putative beta-lactamase-like family DUF5407 PF17401.2 KND98016.1 - 0.066 13.5 0.3 0.15 12.4 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5407) LSM PF01423.22 KND98017.1 - 1.6e-15 56.5 0.2 2.4e-15 56.0 0.2 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KND98017.1 - 0.1 12.2 0.0 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 Hfq protein Hus1 PF04005.12 KND98018.1 - 1.1e-67 228.2 1.4 1.3e-67 228.0 1.4 1.0 1 0 0 1 1 1 1 Hus1-like protein HipN PF18253.1 KND98018.1 - 0.14 11.9 0.2 2.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Hsp70-interacting protein N N-terminal domain Aminotran_5 PF00266.19 KND98019.1 - 1.5e-37 129.4 0.0 1.8e-37 129.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Mog1 PF04603.12 KND98019.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Ran-interacting Mog1 protein GTP_EFTU PF00009.27 KND98020.1 - 7.2e-49 166.0 0.0 1.1e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KND98020.1 - 6.2e-39 132.4 6.9 6.2e-39 132.4 6.9 2.2 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KND98020.1 - 7.7e-21 73.9 0.0 1.6e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KND98020.1 - 1.6e-07 31.6 0.0 3.7e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KND98020.1 - 5.1e-05 23.3 0.1 0.00022 21.3 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 KND98020.1 - 0.00021 21.0 0.0 0.00038 20.1 0.0 1.4 1 0 0 1 1 1 1 Ras family RF3_C PF16658.5 KND98020.1 - 0.0004 20.2 0.2 0.0021 17.9 0.0 2.1 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 KND98020.1 - 0.0026 17.8 0.0 0.01 15.9 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II SRPRB PF09439.10 KND98020.1 - 0.014 14.8 0.0 0.043 13.3 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 KND98020.1 - 0.03 14.3 0.0 0.073 13.1 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Roc PF08477.13 KND98020.1 - 0.075 13.3 0.0 0.2 11.8 0.0 1.8 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase LBR_tudor PF09465.10 KND98020.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain PALP PF00291.25 KND98021.1 - 1.8e-78 264.0 0.0 2.3e-78 263.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KND98021.1 - 1e-42 143.8 0.2 1e-24 86.1 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase DUF4993 PF16384.5 KND98021.1 - 0.058 12.4 0.0 0.081 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function EF-hand_1 PF00036.32 KND98022.1 - 1.3e-11 43.1 0.8 0.00028 20.2 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 KND98022.1 - 3.8e-10 38.8 0.5 0.0003 20.1 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KND98022.1 - 2.6e-09 36.2 3.0 0.017 15.0 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 KND98022.1 - 1.5e-08 35.0 2.8 1.3e-05 25.5 0.1 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KND98022.1 - 0.00092 19.0 1.9 0.074 12.9 0.1 3.8 3 2 1 4 4 4 1 EF-hand domain pair TFIIA PF03153.13 KND98022.1 - 0.2 11.6 24.2 0.25 11.3 24.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_11 PF00457.17 KND98022.1 - 7.3 6.2 8.5 17 5.0 8.3 1.6 2 0 0 2 2 2 0 Glycosyl hydrolases family 11 Per1 PF04080.13 KND98025.1 - 1.5e-81 273.9 12.4 2e-81 273.5 12.4 1.1 1 0 0 1 1 1 1 Per1-like family Phage_XkdX PF09693.10 KND98025.1 - 0.19 11.8 0.6 0.48 10.5 0.6 1.7 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) OST_IS PF18246.1 KND98027.1 - 0.11 12.8 0.0 0.14 12.5 0.0 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase Insert domain GKAP PF03359.13 KND98028.1 - 0.62 9.6 5.7 0.15 11.6 2.6 1.6 2 0 0 2 2 2 0 Guanylate-kinase-associated protein (GKAP) protein PH_11 PF15413.6 KND98029.1 - 7.1e-15 55.3 0.1 2.9e-14 53.3 0.1 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain MMM1 PF10296.9 KND98029.1 - 2e-06 27.1 0.0 8.6e-06 25.0 0.0 2.1 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 PH PF00169.29 KND98029.1 - 0.0031 18.0 0.2 0.078 13.5 0.2 2.8 1 1 0 1 1 1 1 PH domain PI3_PI4_kinase PF00454.27 KND98030.1 - 1.7e-49 168.9 0.2 1.7e-49 168.9 0.2 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KND98030.1 - 5e-23 81.9 5.0 1.8e-22 80.0 5.0 1.9 1 1 0 1 1 1 1 FAT domain UME PF08064.13 KND98030.1 - 3e-21 75.2 5.2 4e-21 74.8 0.5 3.8 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.20 KND98030.1 - 7.7e-13 48.0 0.0 1.6e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 FATC domain CKS PF01111.19 KND98031.1 - 9.8e-33 112.2 0.1 1.3e-32 111.9 0.1 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit PRMT5 PF05185.16 KND98032.1 - 1.7e-39 135.4 0.0 3e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 KND98032.1 - 2.7e-19 69.7 0.5 5.8e-19 68.6 0.5 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 KND98032.1 - 3.5e-06 27.6 0.0 2.2e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KND98032.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 KND98032.1 - 0.11 13.1 0.0 0.26 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KND98032.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Cir_N PF10197.9 KND98033.1 - 9.7e-14 51.3 11.5 9.7e-14 51.3 11.5 2.8 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR CWC25 PF12542.8 KND98033.1 - 1.2e-10 42.2 0.2 1.2e-10 42.2 0.2 2.9 2 1 1 3 3 3 1 Pre-mRNA splicing factor CTP_transf_1 PF01148.20 KND98036.1 - 6.4e-79 265.5 14.2 8.7e-79 265.0 14.2 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family CaKB PF03185.15 KND98036.1 - 0.056 13.1 0.1 0.093 12.4 0.1 1.3 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit DUF962 PF06127.11 KND98036.1 - 2.6 8.2 7.4 4.5 7.4 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF962) SPX PF03105.19 KND98037.1 - 0.024 14.5 5.2 0.03 14.3 5.2 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 KND98037.1 - 0.15 10.9 3.6 0.17 10.7 3.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KND98037.1 - 0.31 9.5 5.3 0.4 9.2 5.3 1.1 1 0 0 1 1 1 0 Macoilin family IQCJ-SCHIP1 PF15157.6 KND98037.1 - 1.5 8.6 5.9 3.2 7.6 5.9 1.5 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif RAP1 PF07218.11 KND98037.1 - 8.3 4.6 13.6 12 4.0 13.6 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MIOX PF05153.15 KND98038.1 - 1.1e-119 398.6 5.6 1.6e-119 398.0 5.6 1.3 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 KND98038.1 - 0.025 14.8 0.3 0.87 9.8 0.0 2.6 1 1 1 2 2 2 0 HD domain Complex1_51K PF01512.17 KND98039.1 - 9e-46 155.5 0.0 2.4e-45 154.1 0.0 1.7 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KND98039.1 - 1.4e-28 98.8 0.1 2.8e-28 97.8 0.1 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KND98039.1 - 1.4e-06 28.0 0.0 3.6e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 SLBB domain Glyco_transf_15 PF01793.16 KND98040.1 - 1.5e-105 353.1 12.5 1.9e-105 352.7 12.5 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ebp2 PF05890.12 KND98041.1 - 4.4e-87 292.0 20.8 4.4e-87 292.0 20.8 2.6 3 0 0 3 3 3 1 Eukaryotic rRNA processing protein EBP2 polyprenyl_synt PF00348.17 KND98042.1 - 2.7e-95 318.3 0.1 3.3e-95 318.0 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase UcrQ PF02939.16 KND98043.1 - 2.4e-31 107.5 0.9 2.7e-31 107.3 0.9 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 KND98043.1 - 0.076 13.4 0.0 0.096 13.1 0.0 1.3 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 Ribosomal_L22 PF00237.19 KND98045.1 - 8e-37 125.6 0.3 1.2e-36 125.0 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e SWIRM PF04433.17 KND98046.1 - 1.1e-30 105.8 0.7 1.7e-29 102.0 0.1 2.5 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KND98046.1 - 1.4e-20 73.0 0.4 3e-20 71.9 0.4 1.5 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KND98046.1 - 1.6e-07 31.4 0.1 3.2e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KND98046.1 - 0.00015 21.9 0.0 0.00037 20.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain GTP_EFTU PF00009.27 KND98048.1 - 3e-32 111.8 0.0 4.4e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KND98048.1 - 1.3e-16 60.5 0.0 2.3e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KND98048.1 - 2.2e-16 59.6 0.0 1.2e-15 57.3 0.0 2.3 3 0 0 3 3 3 1 Elongation factor G C-terminus EFTUD2 PF16004.5 KND98048.1 - 5.6e-06 26.9 1.5 1.3e-05 25.8 1.5 1.6 1 1 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus MMR_HSR1 PF01926.23 KND98048.1 - 1.3e-05 25.3 0.0 2.9e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KND98048.1 - 0.0013 18.9 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EFG_II PF14492.6 KND98048.1 - 0.0062 16.6 0.0 0.021 14.9 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II FeoB_N PF02421.18 KND98048.1 - 0.03 13.9 0.2 9.4 5.7 0.1 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KND98048.1 - 0.048 13.6 0.1 14 5.5 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase RNA_pol_Rpb4 PF03874.16 KND98049.1 - 1.2e-31 109.6 7.8 1.7e-31 109.1 7.8 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 GCV_T PF01571.21 KND98049.1 - 0.046 13.1 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain Pkinase PF00069.25 KND98050.1 - 3.7e-51 174.0 0.0 1.3e-50 172.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND98050.1 - 2.8e-22 79.2 0.0 5e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KND98050.1 - 1.8e-05 24.8 0.0 3.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND98050.1 - 0.0024 17.5 0.5 0.0041 16.7 0.5 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KND98050.1 - 0.026 14.1 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KND98050.1 - 0.029 13.7 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tim17 PF02466.19 KND98051.1 - 2.3e-31 108.4 10.3 3e-31 108.0 10.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Phage_holin_3_3 PF16083.5 KND98051.1 - 0.54 10.4 11.9 1.2 9.3 5.8 2.7 2 1 1 3 3 3 0 LydA holin phage, holin superfamily III AA_permease_2 PF13520.6 KND98053.1 - 9.4e-49 166.4 50.6 1.2e-48 166.0 50.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KND98053.1 - 1.5e-31 109.5 45.5 2e-31 109.2 45.5 1.0 1 0 0 1 1 1 1 Amino acid permease MadM PF03818.13 KND98053.1 - 3.8 7.5 10.0 0.11 12.3 0.5 3.5 4 0 0 4 4 4 0 Malonate/sodium symporter MadM subunit DUF1129 PF06570.11 KND98053.1 - 6.6 6.2 13.2 4.4 6.7 5.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) Ribosomal_L1 PF00687.21 KND98054.1 - 1.1e-38 133.0 0.2 1.7e-38 132.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Palm_thioest PF02089.15 KND98055.1 - 6.1e-71 239.1 0.0 6.9e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 KND98055.1 - 0.0068 15.9 0.1 0.011 15.3 0.1 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) DUF98 PF01947.16 KND98055.1 - 0.088 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 p-hydroxybenzoic acid synthase cwf18 PF08315.12 KND98057.1 - 2.8e-05 24.8 7.6 5.8e-05 23.8 7.6 1.5 1 1 0 1 1 1 1 cwf18 pre-mRNA splicing factor CAF1C_H4-bd PF12265.8 KND98060.1 - 4.6e-19 68.4 0.4 1.4e-18 66.9 0.2 1.9 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KND98060.1 - 1.1e-08 35.5 18.4 0.011 16.5 1.2 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND98060.1 - 9.4e-08 32.3 1.1 0.092 13.1 0.0 4.5 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KND98060.1 - 0.00015 21.7 2.1 0.23 11.3 0.0 3.5 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Vps51 PF08700.11 KND98061.1 - 2.9e-08 33.7 0.8 6.1e-08 32.6 0.8 1.6 1 1 0 1 1 1 1 Vps51/Vps67 Methyltransf_31 PF13847.6 KND98062.1 - 5.1e-24 84.8 0.1 7e-24 84.4 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND98062.1 - 2.7e-09 37.6 0.0 4.5e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND98062.1 - 2.5e-07 31.3 0.0 5e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND98062.1 - 9.7e-06 25.5 0.0 1.4e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND98062.1 - 6.3e-05 23.5 0.0 0.00013 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KND98062.1 - 0.0011 18.9 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KND98062.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Ran_BP1 PF00638.18 KND98063.1 - 1e-25 90.4 0.1 1.8e-25 89.6 0.1 1.4 1 0 0 1 1 1 1 RanBP1 domain zf-C3HC4_3 PF13920.6 KND98064.1 - 8.2e-09 35.2 6.0 8.2e-09 35.2 6.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KND98064.1 - 8.6e-09 35.6 9.8 8.6e-09 35.6 9.8 2.2 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 KND98064.1 - 3.2e-08 33.3 7.7 3.2e-08 33.3 7.7 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KND98064.1 - 3.5e-08 33.2 9.8 3.5e-08 33.2 9.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KND98064.1 - 8e-08 32.2 8.1 2.2e-07 30.8 8.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KND98064.1 - 1.2e-07 31.4 10.6 1.2e-07 31.4 10.6 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KND98064.1 - 2.7e-06 27.2 8.9 2.7e-06 27.2 8.9 2.2 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KND98064.1 - 5.8e-06 26.4 7.7 5.8e-06 26.4 7.7 2.6 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KND98064.1 - 0.0002 21.5 9.5 0.0002 21.5 9.5 2.1 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KND98064.1 - 0.0041 17.0 1.9 0.0041 17.0 1.9 2.5 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KND98064.1 - 0.0047 17.0 4.4 0.013 15.7 4.4 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_11 PF17123.5 KND98064.1 - 0.23 11.2 7.9 0.6 9.9 7.9 1.8 1 0 0 1 1 1 0 RING-like zinc finger DZR PF12773.7 KND98064.1 - 2.1 8.4 10.8 12 6.0 0.3 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf-ANAPC11 PF12861.7 KND98064.1 - 2.2 8.4 8.2 0.17 11.9 2.4 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KND98064.1 - 4.1 7.3 14.1 0.096 12.5 6.8 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_14 PF17978.1 KND98064.1 - 5.6 7.5 8.6 0.81 10.2 4.4 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain NTF2 PF02136.20 KND98066.1 - 2.4e-14 53.9 0.1 4.5e-14 53.0 0.1 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Ribosomal_S21 PF01165.20 KND98068.1 - 1.3e-07 31.3 0.0 1.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 DUF1681 PF07933.14 KND98070.1 - 3.5e-05 23.6 0.2 0.0011 18.7 0.2 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1681) ERCC3_RAD25_C PF16203.5 KND98071.1 - 3.2e-126 419.6 0.9 6.3e-126 418.6 0.9 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KND98071.1 - 1.9e-35 121.8 0.0 4.9e-35 120.4 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND98071.1 - 1.1e-15 58.1 0.0 2.2e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KND98071.1 - 3.2e-12 46.8 0.1 6.9e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KND98071.1 - 9.1e-10 37.8 0.0 1.2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KND98071.1 - 4e-05 23.5 0.0 8.5e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SRP40_C PF05022.12 KND98072.1 - 1.6e-24 86.5 3.8 4.3e-24 85.2 3.8 1.7 1 0 0 1 1 1 1 SRP40, C-terminal domain Zip PF02535.22 KND98072.1 - 0.36 10.0 8.0 0.38 9.9 8.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RAP1 PF07218.11 KND98072.1 - 0.76 8.0 17.4 0.67 8.2 17.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 KND98072.1 - 1.3 7.5 18.9 1.3 7.5 18.9 1.2 1 0 0 1 1 1 0 Macoilin family CDC45 PF02724.14 KND98072.1 - 2.2 6.5 16.2 2.2 6.4 16.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 KND98072.1 - 2.2 7.0 21.9 2.3 7.0 21.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Raftlin PF15250.6 KND98072.1 - 3.8 6.2 12.1 4.4 5.9 12.1 1.1 1 0 0 1 1 1 0 Raftlin SDA1 PF05285.12 KND98072.1 - 4.1 6.7 22.3 4.6 6.6 22.3 1.2 1 0 0 1 1 1 0 SDA1 SOBP PF15279.6 KND98072.1 - 6.5 7.3 12.8 7.7 7.0 12.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Menin PF05053.13 KND98072.1 - 9.1 4.5 14.1 11 4.3 14.1 1.1 1 0 0 1 1 1 0 Menin Tmemb_cc2 PF10267.9 KND98072.1 - 9.2 5.3 12.1 11 5.1 12.1 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Abhydrolase_6 PF12697.7 KND98074.1 - 2e-16 61.3 0.0 2.5e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KND98074.1 - 2.2e-09 37.3 0.4 3.7e-09 36.6 0.4 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KND98074.1 - 6.9e-08 32.0 0.2 2.6e-07 30.2 0.2 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KND98074.1 - 1e-05 25.3 0.0 1.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KND98074.1 - 0.00011 21.7 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KND98074.1 - 0.00081 19.3 0.6 0.0077 16.1 0.6 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase PGAP1 PF07819.13 KND98074.1 - 0.002 17.9 0.1 0.0033 17.2 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Chlorophyllase2 PF12740.7 KND98074.1 - 0.0035 16.3 0.0 0.0071 15.3 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme LCAT PF02450.15 KND98074.1 - 0.024 13.8 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Thioesterase PF00975.20 KND98074.1 - 0.11 12.5 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain DUF3589 PF12141.8 KND98075.1 - 8.2e-143 476.6 0.0 9.9e-143 476.3 0.0 1.1 1 0 0 1 1 1 1 Beta-mannosyltransferases Pkinase PF00069.25 KND98076.1 - 8e-63 212.3 0.0 1.2e-62 211.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND98076.1 - 6.7e-48 163.2 0.0 1.1e-47 162.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND98076.1 - 5.4e-05 22.6 0.6 0.00033 20.1 0.0 2.2 3 0 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 KND98076.1 - 0.00044 19.2 0.0 0.0012 17.7 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KND98076.1 - 0.0011 18.9 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KND98076.1 - 0.028 13.4 0.1 0.028 13.4 0.1 2.9 3 0 0 3 3 3 0 Haspin like kinase domain RIO1 PF01163.22 KND98076.1 - 0.12 12.0 0.0 0.36 10.4 0.0 1.7 1 1 0 1 1 1 0 RIO1 family Kdo PF06293.14 KND98076.1 - 0.16 11.3 0.0 0.49 9.7 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3987 PF13148.6 KND98077.1 - 0.12 11.4 9.0 0.33 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Mit_ribos_Mrp51 PF11709.8 KND98078.1 - 6.9e-54 183.8 2.5 1.9e-51 175.8 2.5 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit MDM10 PF12519.8 KND98079.1 - 8.2e-150 499.7 3.4 9.3e-150 499.5 3.4 1.0 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 CDC14 PF08045.11 KND98080.1 - 2.5e-37 128.5 4.8 1.1e-33 116.5 5.9 2.9 1 1 1 2 2 2 2 Cell division control protein 14, SIN component Leptin PF02024.15 KND98080.1 - 0.009 15.8 0.2 0.019 14.8 0.2 1.5 1 0 0 1 1 1 1 Leptin Gpr1_Fun34_YaaH PF01184.19 KND98082.1 - 2.7e-78 262.3 22.3 3.1e-78 262.1 22.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2448 PF10476.9 KND98082.1 - 0.21 11.4 2.0 1.5 8.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) Las1 PF04031.13 KND98084.1 - 1.6e-34 119.3 0.1 2.5e-34 118.6 0.1 1.3 1 0 0 1 1 1 1 Las1-like ATG2_CAD PF13329.6 KND98085.1 - 3.5e-43 147.0 0.1 2.2e-42 144.4 0.0 2.6 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 KND98085.1 - 2.2e-27 95.2 2.8 3.5e-27 94.6 0.1 2.7 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 KND98085.1 - 8.6e-05 22.4 0.7 0.00064 19.5 0.7 2.5 1 1 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Fungal_trans_2 PF11951.8 KND98085.1 - 0.00051 19.0 0.5 0.0016 17.4 0.5 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nucleos_tra2_C PF07662.13 KND98087.1 - 1.5e-63 214.4 1.2 1.5e-63 214.4 1.2 2.3 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KND98087.1 - 4.2e-21 75.3 3.2 4.2e-21 75.3 3.2 3.9 5 0 0 5 5 5 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 KND98087.1 - 4.7 7.5 14.6 0.73 10.1 6.8 3.2 3 0 0 3 3 3 0 Nucleoside recognition Vps35 PF03635.17 KND98088.1 - 8.7e-245 814.7 24.6 1e-244 814.5 24.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 PNGaseA PF12222.8 KND98089.1 - 2e-111 372.9 0.0 2.5e-111 372.6 0.0 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A tRNA_int_endo PF01974.17 KND98090.1 - 2.5e-17 62.7 0.0 4.1e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KND98090.1 - 0.055 13.1 0.0 0.15 11.7 0.0 1.7 1 1 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain zf-CSL PF05207.13 KND98096.1 - 3.8e-20 71.4 0.2 5.7e-20 70.8 0.2 1.3 1 0 0 1 1 1 1 CSL zinc finger Prok-RING_1 PF14446.6 KND98096.1 - 0.15 12.0 2.2 0.31 11.0 2.2 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Ribosomal_S8e PF01201.22 KND98097.1 - 1.7e-57 193.4 2.2 2e-57 193.2 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Ribosomal_L27A PF00828.19 KND98097.1 - 0.015 15.9 5.0 0.027 15.2 5.0 1.3 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF4771 PF15995.5 KND98097.1 - 0.085 13.1 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4771) Peptidase_C1_2 PF03051.15 KND98098.1 - 2.2e-156 521.0 4.3 2.6e-156 520.8 4.3 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KND98098.1 - 1.1e-06 28.9 1.0 0.0068 16.5 1.0 3.3 3 1 1 4 4 4 2 Papain family cysteine protease DUF1307 PF06998.11 KND98098.1 - 0.029 14.4 0.7 0.081 12.9 0.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1307) AA_permease PF00324.21 KND98099.1 - 4.7e-119 398.1 42.7 5.8e-119 397.8 42.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND98099.1 - 2.3e-28 99.2 45.5 3.1e-28 98.8 45.5 1.1 1 0 0 1 1 1 1 Amino acid permease BP28CT PF08146.12 KND98103.1 - 1.7e-41 141.7 2.4 1.7e-41 141.7 2.4 4.3 4 0 0 4 4 4 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KND98103.1 - 1e-09 38.7 0.2 1e-09 38.7 0.2 7.1 8 0 0 8 8 8 1 U3 small nucleolar RNA-associated protein 10 DUF3385 PF11865.8 KND98103.1 - 0.0095 15.9 7.1 1.1 9.2 0.0 5.6 4 2 0 4 4 4 1 Domain of unknown function (DUF3385) Cpn10 PF00166.21 KND98104.1 - 1.5e-30 105.1 0.0 1.7e-30 104.9 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit MARVEL PF01284.23 KND98105.1 - 0.0016 18.5 12.5 0.0026 17.8 12.5 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF2759 PF10958.8 KND98105.1 - 0.01 15.6 2.4 0.028 14.1 2.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2759) Ras PF00071.22 KND98106.1 - 3.7e-52 176.2 0.2 6.5e-52 175.4 0.2 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KND98106.1 - 9e-36 122.7 0.0 1.4e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND98106.1 - 8.7e-16 57.9 0.0 1.1e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KND98106.1 - 3.5e-06 26.5 0.0 4.4e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KND98106.1 - 8.9e-06 25.4 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KND98106.1 - 1.6e-05 25.0 0.0 2.3e-05 24.4 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KND98106.1 - 0.00052 20.0 0.0 0.29 11.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KND98106.1 - 0.0058 16.9 0.1 1.7 8.9 0.0 2.3 2 1 0 2 2 2 2 AAA domain TniB PF05621.11 KND98106.1 - 0.018 14.5 0.0 0.049 13.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein G-alpha PF00503.20 KND98106.1 - 0.02 14.0 0.0 1.1 8.4 0.0 2.6 1 1 1 3 3 3 0 G-protein alpha subunit AAA_16 PF13191.6 KND98106.1 - 0.036 14.4 0.7 0.11 12.8 0.7 1.9 1 1 0 1 1 1 0 AAA ATPase domain DUF3294 PF07957.11 KND98106.1 - 0.11 12.2 0.2 0.17 11.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) MBF1 PF08523.10 KND98107.1 - 4.8e-25 87.8 3.4 4.8e-25 87.8 3.4 2.2 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KND98107.1 - 2.6e-15 56.2 0.4 8.8e-15 54.5 0.3 1.8 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 KND98107.1 - 5.5e-07 29.8 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KND98107.1 - 8e-06 25.8 0.1 1.6e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MAJIN PF15077.6 KND98107.1 - 0.19 11.5 1.5 0.23 11.2 1.5 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein Steroid_dh PF02544.16 KND98109.1 - 5.4e-33 114.1 7.8 5.4e-33 114.1 7.8 1.8 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase SelR PF01641.18 KND98110.1 - 9.1e-50 167.8 0.0 1e-49 167.6 0.0 1.0 1 0 0 1 1 1 1 SelR domain Zn_ribbon_SprT PF17283.2 KND98110.1 - 0.026 14.4 1.8 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain TackOD1 PF18551.1 KND98110.1 - 0.14 11.8 0.3 0.14 11.8 0.3 1.5 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 zf-Mss51 PF13824.6 KND98110.1 - 0.18 11.9 2.6 0.22 11.6 0.2 2.3 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Methyltransf_25 PF13649.6 KND98111.1 - 2.9e-12 47.1 0.0 9.6e-12 45.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KND98111.1 - 1.2e-11 44.6 0.0 1.6e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KND98111.1 - 1.4e-11 44.4 0.1 3.4e-11 43.2 0.1 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND98111.1 - 1.2e-09 38.7 0.0 4.1e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 KND98111.1 - 6.6e-07 28.6 0.1 9.5e-07 28.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 KND98111.1 - 1.5e-06 28.2 0.0 2.4e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KND98111.1 - 1.7e-05 24.8 0.1 2.8e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KND98111.1 - 1.9e-05 24.1 0.0 2.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KND98111.1 - 2e-05 24.2 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KND98111.1 - 0.00012 22.8 0.0 0.00024 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KND98111.1 - 0.0011 18.7 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_32 PF13679.6 KND98111.1 - 0.0079 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KND98111.1 - 0.0089 16.2 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KND98111.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PRMT5 PF05185.16 KND98111.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase TehB PF03848.14 KND98111.1 - 0.021 14.2 0.2 0.052 13.0 0.1 1.7 2 0 0 2 2 2 0 Tellurite resistance protein TehB PCMT PF01135.19 KND98111.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MFS_1 PF07690.16 KND98112.1 - 1.7e-34 119.3 19.3 1.7e-34 119.3 19.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily ERK-JNK_inhib PF15002.6 KND98112.1 - 0.074 12.7 0.6 0.12 12.0 0.6 1.2 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor LIDHydrolase PF10230.9 KND98113.1 - 4.7e-61 206.7 0.3 5.5e-61 206.5 0.3 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 KND98113.1 - 0.0019 17.5 0.1 0.0029 16.9 0.1 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KND98113.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KND98113.1 - 0.027 15.1 0.0 0.03 14.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 KND98113.1 - 0.03 13.8 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) TANGO2 PF05742.12 KND98114.1 - 3.1e-66 224.0 0.0 3.5e-66 223.8 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Pkinase PF00069.25 KND98115.1 - 1.2e-47 162.5 0.0 5.9e-47 160.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND98115.1 - 2.8e-25 89.1 0.1 1.8e-24 86.5 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KND98115.1 - 0.0074 15.7 0.2 0.017 14.5 0.2 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C2HC5 PF06221.13 KND98117.1 - 1.5e-23 82.5 6.9 2.4e-23 81.9 6.9 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type TerY_C PF15616.6 KND98117.1 - 0.035 14.2 0.9 0.072 13.2 0.9 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain Drc1-Sld2 PF11719.8 KND98118.1 - 1.1e-62 213.1 28.3 3.3e-62 211.5 28.3 1.6 1 1 0 1 1 1 1 DNA replication and checkpoint protein RsfS PF02410.15 KND98119.1 - 1.4e-17 63.9 0.0 2.9e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation mRNA_stabil PF13929.6 KND98119.1 - 0.002 17.2 2.6 0.23 10.4 2.6 2.4 1 1 0 1 1 1 1 mRNA stabilisation Exonuc_VIII PF06630.11 KND98119.1 - 0.019 14.8 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII Utp11 PF03998.13 KND98121.1 - 1.2e-65 221.9 35.1 1.3e-65 221.7 35.1 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 KND98121.1 - 0.019 14.3 0.6 0.019 14.3 0.6 2.4 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 Borealin PF10512.9 KND98121.1 - 1.2 9.1 4.1 0.7 9.9 0.2 2.3 2 0 0 2 2 2 0 Cell division cycle-associated protein 8 KTI12 PF08433.10 KND98122.1 - 2.4e-96 322.4 0.0 2.7e-96 322.2 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CLP1_P PF16575.5 KND98122.1 - 0.00021 21.1 0.2 0.00043 20.1 0.0 1.6 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 KND98122.1 - 0.0003 21.0 0.0 0.0015 18.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KND98122.1 - 0.00041 20.9 0.0 0.00086 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KND98122.1 - 0.046 14.0 0.0 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KND98123.1 - 3.6e-13 49.6 0.1 1.3e-12 47.8 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KND98123.1 - 0.0001 22.2 0.2 0.00026 20.9 0.2 1.7 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KND98123.1 - 0.00015 21.3 0.4 0.0048 16.4 0.4 2.4 1 1 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 KND98123.1 - 0.0046 16.3 0.0 0.011 15.1 0.0 1.7 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KND98123.1 - 0.15 12.1 0.7 31 4.6 0.0 3.2 3 1 1 4 4 4 0 Dynamin family Ku PF02735.16 KND98124.1 - 7.5e-21 74.8 0.3 1.7e-20 73.6 0.3 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KND98124.1 - 0.00029 20.7 0.0 0.00082 19.2 0.0 1.8 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain ADPRTs_Tse2 PF18648.1 KND98124.1 - 0.075 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Tse2 ADP-ribosyltransferase toxins Fungal_trans_2 PF11951.8 KND98125.1 - 3.7e-05 22.7 1.3 5.4e-05 22.2 1.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Alpha-amylase_C PF02806.18 KND98126.1 - 5.5e-25 87.7 0.1 2.2e-24 85.7 0.0 2.2 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 KND98126.1 - 2.6e-16 60.1 0.5 5.5e-15 55.8 0.2 2.2 1 1 1 2 2 2 1 Alpha amylase, catalytic domain CBM_48 PF02922.18 KND98126.1 - 5.1e-16 58.8 0.0 1.2e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) GHL6 PF14871.6 KND98126.1 - 0.02 15.0 0.0 0.055 13.6 0.0 1.8 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Glyco_hydro_66 PF13199.6 KND98126.1 - 0.061 12.0 0.7 0.094 11.3 0.7 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 WD40 PF00400.32 KND98127.1 - 5e-29 99.9 20.6 3.8e-06 27.5 0.3 10.1 9 1 1 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND98127.1 - 1.9e-14 53.7 0.2 0.00024 21.4 0.0 6.3 6 2 1 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 KND98127.1 - 0.0084 15.4 0.0 0.055 12.7 0.0 2.3 3 0 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus PD40 PF07676.12 KND98127.1 - 0.0094 15.9 6.5 3.6 7.6 0.0 5.4 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Rav1p_C PF12234.8 KND98127.1 - 0.02 13.4 0.0 0.15 10.5 0.0 2.0 2 0 0 2 2 2 0 RAVE protein 1 C terminal PQQ_3 PF13570.6 KND98127.1 - 0.034 14.7 0.0 9.7 6.8 0.0 3.9 3 0 0 3 3 3 0 PQQ-like domain DUF1668 PF07893.13 KND98127.1 - 0.07 12.5 0.0 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1668) CPSF_A PF03178.15 KND98127.1 - 0.084 12.2 0.0 15 4.8 0.0 2.4 2 0 0 2 2 2 0 CPSF A subunit region Actin PF00022.19 KND98128.1 - 2.2e-112 375.7 0.0 2.6e-112 375.4 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KND98128.1 - 0.013 14.3 0.0 1.2 7.8 0.0 2.6 3 0 0 3 3 3 0 MreB/Mbl protein Mitofilin PF09731.9 KND98129.1 - 6.6e-49 167.3 27.9 1.7e-43 149.4 22.4 2.1 1 1 1 2 2 2 2 Mitochondrial inner membrane protein DASH_Dad1 PF08649.10 KND98129.1 - 0.0012 19.0 2.0 0.036 14.3 0.2 3.0 2 0 0 2 2 2 1 DASH complex subunit Dad1 DUF4837 PF16125.5 KND98129.1 - 0.14 11.2 4.6 0.23 10.4 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4837) PI3K_P85_iSH2 PF16454.5 KND98129.1 - 0.15 11.6 20.1 0.066 12.8 10.5 2.7 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Phasin PF05597.11 KND98129.1 - 0.15 12.0 17.2 1.7 8.6 0.1 3.7 1 1 3 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) RSS_P20 PF11757.8 KND98129.1 - 1.1 9.7 7.0 0.17 12.4 1.6 2.4 2 1 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain Sulfatase PF00884.23 KND98130.1 - 9.4e-73 245.3 0.0 4.6e-72 243.0 0.0 1.8 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KND98130.1 - 0.0002 21.1 0.1 0.2 11.2 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KND98130.1 - 0.002 16.8 0.0 0.0028 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.6 KND98130.1 - 0.0065 17.2 1.2 0.29 11.9 0.3 2.7 2 1 0 2 2 2 1 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 KND98130.1 - 0.0071 16.2 0.1 0.026 14.4 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function DUF4976 PF16347.5 KND98130.1 - 0.066 13.5 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) Cupin_5 PF06172.11 KND98131.1 - 3.2e-42 144.0 0.0 3.7e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) HRXXH PF13933.6 KND98132.1 - 1.3e-94 316.3 0.6 2e-94 315.8 0.6 1.2 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 KND98132.1 - 6.2e-05 23.6 1.2 9.5e-05 23.0 0.0 2.0 2 1 0 2 2 2 1 Lysine-specific metallo-endopeptidase Pox_P4A PF03395.14 KND98132.1 - 0.15 9.6 0.0 0.19 9.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus P4A protein Pkinase PF00069.25 KND98133.1 - 8e-56 189.3 4.2 1e-35 123.4 0.0 2.8 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND98133.1 - 7e-35 120.6 0.1 3.6e-22 78.9 0.0 2.6 2 1 1 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KND98133.1 - 1.6e-05 23.8 0.0 1.6e-05 23.8 0.0 3.2 3 1 0 3 3 3 1 Fungal protein kinase APH PF01636.23 KND98133.1 - 0.012 15.5 0.8 0.11 12.4 0.0 2.7 2 2 1 3 3 3 0 Phosphotransferase enzyme family IMD PF08397.11 KND98133.1 - 6.2 6.1 21.3 3.2 7.1 11.0 2.3 1 1 1 2 2 2 0 IRSp53/MIM homology domain SAICAR_synt PF01259.18 KND98134.1 - 6e-101 337.3 0.3 7.7e-101 336.9 0.3 1.1 1 0 0 1 1 1 1 SAICAR synthetase APS_kinase PF01583.20 KND98136.1 - 3.2e-73 244.8 0.0 4e-73 244.5 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KND98136.1 - 6.7e-06 26.3 0.0 1.4e-05 25.3 0.0 1.6 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.10 KND98136.1 - 0.00022 20.8 0.0 0.00026 20.5 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 KND98136.1 - 0.002 17.5 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 KND98136.1 - 0.0034 17.1 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KND98136.1 - 0.004 17.7 0.0 0.0063 17.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain CPT PF07931.12 KND98136.1 - 0.015 15.2 0.1 0.52 10.1 0.1 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein G-alpha PF00503.20 KND98136.1 - 0.021 14.0 0.1 0.071 12.3 0.0 1.7 1 1 0 2 2 2 0 G-protein alpha subunit CbiA PF01656.23 KND98136.1 - 0.042 13.9 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 KND98136.1 - 0.052 13.9 0.0 0.053 13.9 0.0 1.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KND98136.1 - 0.084 13.4 0.2 0.1 13.1 0.2 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KND98136.1 - 0.17 12.4 0.0 0.28 11.7 0.0 1.3 1 1 0 1 1 1 0 ABC transporter Snf7 PF03357.21 KND98137.1 - 1.1e-27 96.7 25.7 5.3e-27 94.5 22.6 2.0 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 KND98137.1 - 3.8e-05 23.7 6.0 6.9e-05 22.8 5.9 1.5 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway NA37 PF04245.13 KND98137.1 - 0.0049 16.4 2.9 0.0053 16.3 2.4 1.3 1 1 0 1 1 1 1 37-kD nucleoid-associated bacterial protein Uds1 PF15456.6 KND98137.1 - 0.019 15.1 0.3 0.019 15.1 0.3 2.5 2 0 0 2 2 2 0 Up-regulated During Septation DUF2652 PF10851.8 KND98137.1 - 0.028 14.5 2.2 0.03 14.5 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2652) CtIP_N PF10482.9 KND98137.1 - 0.72 9.9 9.9 0.12 12.4 5.0 2.2 2 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Sec16_N PF12935.7 KND98137.1 - 6.2 6.9 11.9 12 6.0 11.5 1.6 1 1 0 1 1 1 0 Vesicle coat trafficking protein Sec16 N-terminus LUC7 PF03194.15 KND98137.1 - 9.7 5.8 16.3 2.9e+03 -2.3 16.3 2.1 1 1 0 1 1 1 0 LUC7 N_terminus Cu-oxidase_2 PF07731.14 KND98138.1 - 1.8e-47 160.5 10.2 4.2e-42 143.1 0.5 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KND98138.1 - 3.2e-45 153.0 1.1 1.1e-42 144.8 0.2 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KND98138.1 - 1e-35 123.2 2.8 1.3e-31 109.9 0.2 2.9 3 0 0 3 3 3 2 Multicopper oxidase C1q PF00386.21 KND98138.1 - 0.017 15.3 0.0 5.2 7.3 0.0 2.6 2 0 0 2 2 2 0 C1q domain Cupredoxin_1 PF13473.6 KND98138.1 - 0.087 12.9 0.0 24 5.1 0.0 3.1 3 0 0 3 3 3 0 Cupredoxin-like domain GA PF01468.17 KND98139.1 - 0.51 10.6 2.2 7 7.0 0.1 2.6 2 0 0 2 2 2 0 GA module Tup_N PF08581.10 KND98140.1 - 1.4 9.3 24.9 0.088 13.1 13.0 3.5 2 2 1 3 3 3 0 Tup N-terminal Spc7 PF08317.11 KND98140.1 - 3.7 6.3 31.8 0.56 9.0 16.9 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Myb_DNA-binding PF00249.31 KND98141.1 - 1.4e-21 76.4 11.8 6.1e-10 39.1 1.2 3.8 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KND98141.1 - 3.7e-20 71.9 8.2 4.1e-14 52.6 1.8 3.4 3 1 1 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KND98141.1 - 0.015 15.7 11.8 0.021 15.2 1.8 3.3 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain TEA PF01285.18 KND98141.1 - 0.019 15.0 2.1 3.1 7.9 0.1 3.1 2 1 0 2 2 2 0 TEA/ATTS domain Atg29_N PF18388.1 KND98141.1 - 0.12 12.2 5.8 3.2 7.7 0.3 3.6 4 0 0 4 4 4 0 Atg29 N-terminal domain MADF_DNA_bdg PF10545.9 KND98141.1 - 0.52 10.7 7.6 8.5 6.8 2.6 3.3 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Sec5 PF15469.6 KND98142.1 - 3.2e-38 131.4 15.0 3.2e-38 131.4 15.0 3.6 4 1 0 4 4 4 1 Exocyst complex component Sec5 Vps51 PF08700.11 KND98142.1 - 0.0017 18.4 1.9 0.0017 18.4 1.9 3.7 4 0 0 4 4 4 1 Vps51/Vps67 Tsi6 PF18660.1 KND98142.1 - 0.0034 17.4 3.4 0.088 12.9 0.1 3.8 3 0 0 3 3 3 1 Tsi6 Sigma70_ECF PF07638.11 KND98142.1 - 0.019 14.8 0.1 0.07 13.0 0.0 2.0 2 0 0 2 2 2 0 ECF sigma factor YliH PF10799.8 KND98142.1 - 0.12 12.3 0.9 0.75 9.7 0.0 2.8 3 0 0 3 3 3 0 Biofilm formation protein (YliH/bssR) FTR1 PF03239.14 KND98143.1 - 1.3e-95 320.1 7.1 1.6e-95 319.8 7.1 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family PHO4 PF01384.20 KND98143.1 - 2.7 7.0 5.5 0.99 8.4 0.1 2.2 1 1 1 2 2 2 0 Phosphate transporter family Alba PF01918.21 KND98146.1 - 5e-11 42.3 1.9 1e-10 41.3 0.6 2.0 2 1 1 3 3 3 1 Alba Ribosomal_S8 PF00410.19 KND98146.1 - 0.073 13.0 0.9 0.14 12.1 0.9 1.6 1 1 0 1 1 1 0 Ribosomal protein S8 Chordopox_L2 PF05803.12 KND98147.1 - 0.028 14.3 0.2 2.3 8.1 0.0 2.1 2 0 0 2 2 2 0 Chordopoxvirus L2 protein NFACT-R_1 PF05670.13 KND98148.1 - 3.5e-35 120.9 0.4 7.3e-35 119.9 0.4 1.6 1 0 0 1 1 1 1 NFACT protein RNA binding domain RabGAP-TBC PF00566.18 KND98150.1 - 2.7e-33 115.4 5.7 4.8e-33 114.6 5.7 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Not1 PF04054.15 KND98152.1 - 2.1e-109 365.8 1.0 6.1e-109 364.3 1.0 1.8 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KND98152.1 - 7.8e-84 280.5 2.9 7.8e-84 280.5 2.9 2.5 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_HEAT_N PF16419.5 KND98152.1 - 3.2e-65 220.0 1.2 1.4e-64 217.9 1.2 2.3 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat CNOT1_TTP_bind PF16417.5 KND98152.1 - 1.2e-48 164.8 2.1 1.2e-48 164.8 2.1 2.2 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 KND98152.1 - 7.5e-35 120.0 3.3 2.1e-34 118.6 3.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 KND98152.1 - 1.1e-15 58.1 0.4 3.8e-15 56.3 0.4 2.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF3802 PF12290.8 KND98152.1 - 0.0023 18.4 0.2 0.06 13.8 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3802) DUF2420 PF10336.9 KND98152.1 - 0.012 15.6 0.3 0.091 12.8 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2420) UQ_con PF00179.26 KND98153.1 - 8.7e-44 148.6 0.1 1.2e-43 148.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 KND98153.1 - 2.1e-19 69.1 0.1 4e-19 68.2 0.1 1.5 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 KND98153.1 - 0.00013 21.7 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KND98153.1 - 0.066 13.5 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 RWD domain UBA PF00627.31 KND98153.1 - 0.099 12.6 1.3 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 UBA/TS-N domain DBR1 PF05011.13 KND98154.1 - 5.3e-23 82.0 0.1 1e-22 81.0 0.1 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KND98154.1 - 0.00013 22.5 0.0 0.00019 22.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NAD_binding_1 PF00175.21 KND98155.1 - 1e-28 100.1 0.0 1.8e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KND98155.1 - 2.8e-23 82.1 0.0 4.9e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KND98155.1 - 1.8e-05 24.9 0.0 0.00042 20.5 0.0 2.3 1 1 0 2 2 2 1 Ferric reductase NAD binding domain Carb_kinase PF01256.17 KND98156.1 - 2.4e-49 168.0 0.0 2.6e-48 164.6 0.0 1.9 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KND98156.1 - 0.00015 21.2 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase NS3_envE PF02723.14 KND98158.1 - 0.064 13.3 0.3 0.084 13.0 0.3 1.2 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E NAD_Gly3P_dh_N PF01210.23 KND98159.1 - 1.5e-51 174.5 0.1 2.6e-51 173.7 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KND98159.1 - 8.1e-40 136.4 0.0 1.7e-39 135.4 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 KND98159.1 - 0.0071 16.9 0.1 0.13 12.8 0.1 2.4 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NUDIX PF00293.28 KND98160.1 - 5e-09 36.3 0.1 1.9e-08 34.4 0.0 2.1 2 1 0 2 2 2 1 NUDIX domain Brix PF04427.18 KND98162.1 - 1.4e-45 155.8 1.1 2.3e-45 155.1 1.1 1.3 1 0 0 1 1 1 1 Brix domain TT_ORF2 PF02957.15 KND98162.1 - 0.086 13.8 4.5 0.17 12.8 4.5 1.4 1 0 0 1 1 1 0 TT viral ORF2 AIF_C PF14721.6 KND98162.1 - 0.11 12.8 2.8 0.13 12.6 1.7 1.8 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FGF-BP1 PF06473.12 KND98162.1 - 0.76 9.6 8.6 1.5 8.6 8.4 1.6 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) NARP1 PF12569.8 KND98162.1 - 1.2 7.9 11.7 1.7 7.4 11.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Presenilin PF01080.17 KND98162.1 - 1.9 7.1 6.2 2.9 6.6 6.2 1.2 1 0 0 1 1 1 0 Presenilin DEAD PF00270.29 KND98163.1 - 6.3e-49 166.1 0.0 1.1e-48 165.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND98163.1 - 2.4e-30 105.1 0.0 8.7e-30 103.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND98163.1 - 8.3e-06 25.9 0.0 1.9e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KND98163.1 - 0.00022 20.5 1.2 0.0003 20.1 0.1 1.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase AAA_30 PF13604.6 KND98163.1 - 0.0022 17.7 0.0 0.0046 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain zf-RING_2 PF13639.6 KND98164.1 - 3.2e-09 37.0 7.5 3.9e-09 36.7 2.5 2.5 3 0 0 3 3 2 1 Ring finger domain zf-RING_11 PF17123.5 KND98164.1 - 5e-07 29.3 3.4 1.5e-06 27.9 3.4 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KND98164.1 - 2.8e-06 27.1 5.1 3.2e-05 23.7 1.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KND98164.1 - 9.7e-05 21.9 3.9 0.00042 19.9 2.1 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 KND98164.1 - 0.00011 22.0 3.5 0.00038 20.3 1.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KND98164.1 - 0.0015 18.5 3.0 0.0015 18.5 3.0 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KND98164.1 - 0.0024 17.8 3.9 0.042 13.8 2.3 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 KND98164.1 - 0.0092 16.3 3.4 0.0092 16.3 3.4 2.7 2 2 1 3 3 3 1 RING-H2 zinc finger domain zf-RING-like PF08746.11 KND98164.1 - 0.031 14.6 1.9 0.031 14.6 1.9 1.9 2 0 0 2 2 2 0 RING-like domain zf-C3HC4_3 PF13920.6 KND98164.1 - 0.061 13.2 4.3 0.77 9.7 1.6 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KND98164.1 - 0.067 13.3 1.2 0.067 13.3 1.2 2.0 2 1 0 2 2 2 0 RING-variant domain Atracotoxin PF05353.11 KND98164.1 - 0.099 12.7 0.7 0.26 11.3 0.7 1.6 1 0 0 1 1 1 0 Delta Atracotoxin Prok-RING_1 PF14446.6 KND98164.1 - 0.54 10.2 9.5 2.8 7.9 0.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 AA_permease PF00324.21 KND98165.1 - 6.6e-95 318.5 43.6 8.2e-95 318.2 43.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND98165.1 - 7.3e-27 94.3 50.4 9.1e-27 93.9 50.4 1.1 1 0 0 1 1 1 1 Amino acid permease NCE101 PF11654.8 KND98165.1 - 0.22 11.3 0.5 19 5.0 0.1 2.5 2 0 0 2 2 2 0 Non-classical export protein 1 Med21 PF11221.8 KND98166.1 - 1.1e-46 158.6 1.2 1.4e-46 158.3 1.2 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex EspA PF03433.13 KND98166.1 - 0.032 14.1 0.2 0.069 13.0 0.2 1.5 1 0 0 1 1 1 0 EspA-like secreted protein LepB_GAP_N PF18172.1 KND98166.1 - 0.057 13.3 0.5 0.1 12.5 0.1 1.6 2 0 0 2 2 2 0 LepB GAP domain N-terminal subdomain DUF948 PF06103.11 KND98166.1 - 0.11 12.7 0.7 6.5 7.1 0.1 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) PMT PF02366.18 KND98167.1 - 9.2e-65 218.6 15.7 9.2e-65 218.6 15.7 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KND98167.1 - 2.9e-48 164.1 15.6 2.9e-48 164.1 15.6 2.2 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KND98167.1 - 7.8e-22 78.0 2.5 1e-21 77.7 1.7 1.5 1 1 0 1 1 1 1 MIR domain DUF2518 PF10726.9 KND98167.1 - 0.077 12.6 1.0 0.32 10.6 1.0 2.0 1 0 0 1 1 1 0 Protein of function (DUF2518) Ins145_P3_rec PF08709.11 KND98167.1 - 0.11 11.6 0.4 2.2 7.4 0.2 2.1 1 1 1 2 2 2 0 Inositol 1,4,5-trisphosphate/ryanodine receptor NADH-u_ox-rdase PF10785.9 KND98167.1 - 0.15 12.8 0.5 3.1 8.6 0.5 3.0 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit SR-25 PF10500.9 KND98170.1 - 0.014 15.0 6.9 0.016 14.9 6.9 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF5316 PF17247.2 KND98170.1 - 0.065 13.3 0.2 0.12 12.4 0.1 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5316) Rsm22 PF09243.10 KND98172.1 - 9.4e-24 84.1 2.0 6e-10 38.8 1.9 4.2 2 2 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 KND98172.1 - 4.3e-05 23.4 0.0 0.00012 21.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain ApoO PF09769.9 KND98173.1 - 4.8e-38 130.1 0.0 1e-37 129.0 0.0 1.5 1 0 0 1 1 1 1 Apolipoprotein O PEP-utilisers_N PF05524.13 KND98174.1 - 0.026 14.7 0.0 0.088 13.0 0.0 1.9 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Mito_carr PF00153.27 KND98175.1 - 7.8e-61 202.0 3.3 7e-25 86.8 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein PsaL PF02605.15 KND98175.1 - 0.029 14.0 0.9 0.073 12.7 0.2 2.0 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI Serine_protease PF18405.1 KND98175.1 - 0.057 12.6 0.1 2.3 7.3 0.1 2.7 2 1 1 3 3 3 0 Gammaproteobacterial serine protease FOXO_KIX_bdg PF16675.5 KND98176.1 - 0.078 13.3 2.2 3.3 8.1 0.3 2.4 2 1 0 2 2 2 0 KIX-binding domain of forkhead box O, CR2 Raptor_N PF14538.6 KND98177.1 - 1.6e-67 226.0 0.0 3.1e-67 225.1 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 KND98177.1 - 3e-06 27.8 2.4 2.7 9.0 0.1 6.2 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND98177.1 - 2.2e-05 24.6 0.1 0.066 13.5 0.0 3.9 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain HEAT PF02985.22 KND98177.1 - 0.00053 20.0 0.4 2.9 8.4 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 KND98177.1 - 0.0028 17.7 0.0 0.097 12.7 0.0 2.8 1 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KND98177.1 - 0.09 13.2 0.0 0.67 10.4 0.0 2.5 2 0 0 2 2 2 0 HEAT repeats MFAP1 PF06991.11 KND98180.1 - 7.2e-09 35.8 14.1 2.1e-06 27.8 11.4 3.0 2 1 0 2 2 2 2 Microfibril-associated/Pre-mRNA processing CDO_I PF05995.12 KND98182.1 - 1.6e-41 141.5 0.0 2.1e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KND98182.1 - 0.016 14.7 0.6 0.79 9.1 0.6 2.1 1 1 0 1 1 1 0 PCO_ADO SLAC1 PF03595.17 KND98183.1 - 3.1e-68 230.4 45.0 3.5e-68 230.2 45.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Trs65 PF12735.7 KND98185.1 - 1.7e-55 188.7 4.6 1e-54 186.1 4.6 2.0 1 1 0 1 1 1 1 TRAPP trafficking subunit Trs65 TFIID_30kDa PF03540.13 KND98187.1 - 2.9e-25 87.9 0.0 9.2e-25 86.4 0.0 1.9 2 0 0 2 2 2 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 KND98187.1 - 0.31 11.6 1.9 0.54 10.8 0.1 2.1 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Zn_ribbon_17 PF17120.5 KND98188.1 - 3.3e-17 61.8 12.3 8.1e-17 60.6 12.3 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 KND98188.1 - 8.1e-05 23.3 19.8 0.021 15.7 0.1 6.1 5 0 0 5 5 5 2 WD domain, G-beta repeat C1_2 PF03107.16 KND98188.1 - 0.013 15.7 0.1 0.035 14.4 0.1 1.7 1 0 0 1 1 1 0 C1 domain RWD PF05773.22 KND98188.1 - 0.042 14.1 0.3 0.12 12.7 0.3 1.7 1 0 0 1 1 1 0 RWD domain zf-RING_2 PF13639.6 KND98188.1 - 0.52 10.7 9.9 1.4 9.3 9.9 1.8 1 0 0 1 1 1 0 Ring finger domain C1_1 PF00130.22 KND98188.1 - 0.59 10.1 6.6 0.12 12.3 2.8 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ANAPC11 PF12861.7 KND98188.1 - 1.5 8.9 6.4 5 7.2 6.4 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger adh_short PF00106.25 KND98189.1 - 1.1e-05 25.0 0.0 7.2e-05 22.3 0.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND98189.1 - 0.0048 16.5 0.0 0.99 8.9 0.0 2.5 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase MFS_1 PF07690.16 KND98191.1 - 1.2e-36 126.4 16.8 1.2e-36 126.4 16.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND98191.1 - 5.3e-05 22.3 21.8 0.00013 21.0 21.8 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter HECT PF00632.25 KND98192.1 - 8.3e-70 235.7 0.1 1.4e-69 235.0 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) TSLP PF15216.6 KND98192.1 - 0.057 13.7 0.4 0.21 11.8 0.4 1.9 1 0 0 1 1 1 0 Thymic stromal lymphopoietin SDA1 PF05285.12 KND98192.1 - 3.1 7.1 21.9 4.9 6.5 21.9 1.2 1 0 0 1 1 1 0 SDA1 F-actin_cap_A PF01267.17 KND98193.1 - 3.1e-52 177.7 0.5 3.5e-52 177.4 0.5 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit PilJ PF13675.6 KND98195.1 - 0.018 15.1 0.1 0.021 14.8 0.1 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Sec20 PF03908.13 KND98195.1 - 0.024 14.5 0.3 0.055 13.4 0.3 1.6 1 1 0 1 1 1 0 Sec20 Syntaxin_2 PF14523.6 KND98195.1 - 0.039 14.3 2.4 0.049 14.0 2.4 1.1 1 0 0 1 1 1 0 Syntaxin-like protein DDE_Tnp_1_7 PF13843.6 KND98195.1 - 0.073 12.4 0.2 0.079 12.3 0.2 1.1 1 0 0 1 1 1 0 Transposase IS4 HalX PF08663.10 KND98195.1 - 0.091 13.1 0.1 6.8 7.1 0.1 2.1 1 1 1 2 2 2 0 HalX domain DUF1043 PF06295.12 KND98195.1 - 0.094 12.7 0.6 0.17 11.9 0.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) VHS PF00790.19 KND98196.1 - 1.6e-28 99.3 0.7 1.6e-28 99.3 0.7 2.0 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.28 KND98196.1 - 1.2e-15 56.8 0.0 2.1e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KND98196.1 - 1.2e-12 47.3 0.0 2.3e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KND98196.1 - 6.2e-12 45.2 0.0 1.1e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KND98196.1 - 0.016 15.5 0.9 0.098 13.0 0.9 2.4 1 0 0 1 1 1 0 GAT domain HAGH_C PF16123.5 KND98196.1 - 0.034 14.7 3.3 0.062 13.8 0.1 2.4 2 0 0 2 2 2 0 Hydroxyacylglutathione hydrolase C-terminus UIM PF02809.20 KND98196.1 - 0.31 11.1 7.2 0.053 13.5 3.0 2.0 2 0 0 2 2 2 0 Ubiquitin interaction motif TRAM_LAG1_CLN8 PF03798.16 KND98197.1 - 2.4e-36 125.4 22.9 2.4e-36 125.4 22.9 2.3 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KND98197.1 - 5.7e-19 67.5 0.5 5.7e-19 67.5 0.5 2.3 2 0 0 2 2 2 1 TRAM1-like protein Ribosomal_S2 PF00318.20 KND98198.1 - 7.4e-63 211.6 5.7 1.8e-62 210.4 0.1 2.9 2 1 0 2 2 2 1 Ribosomal protein S2 Pex14_N PF04695.13 KND98198.1 - 5.1 7.7 6.8 22 5.7 0.1 2.3 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CS PF04969.16 KND98199.1 - 0.0011 19.9 0.0 0.0024 18.8 0.0 1.6 1 1 0 1 1 1 1 CS domain Syja_N PF02383.18 KND98201.1 - 1e-77 261.6 3.1 1.2e-77 261.3 0.1 2.2 2 0 0 2 2 2 1 SacI homology domain SNF5 PF04855.12 KND98203.1 - 6.4e-48 163.6 3.1 2.2e-29 102.9 0.5 2.2 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 Tic110 PF16940.5 KND98203.1 - 0.059 11.9 0.0 0.092 11.2 0.0 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter CID_GANP PF16766.5 KND98204.1 - 0.033 14.4 0.4 0.067 13.4 0.0 1.6 2 0 0 2 2 2 0 Binding region of GANP to ENY2 PARG_cat PF05028.14 KND98204.1 - 0.037 13.3 0.1 0.038 13.3 0.1 1.1 1 0 0 1 1 1 0 Poly (ADP-ribose) glycohydrolase (PARG) dCMP_cyt_deam_1 PF00383.23 KND98205.1 - 7.9e-08 32.1 0.1 1.3e-07 31.4 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KND98205.1 - 2.5e-06 27.3 0.0 7.6e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 MafB19-like deaminase Telomerase_RBD PF12009.8 KND98206.1 - 1.3e-20 73.8 2.5 4.1e-20 72.2 2.5 1.9 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 KND98206.1 - 3e-11 43.3 0.2 3.2e-08 33.4 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) AIP3 PF03915.13 KND98207.1 - 6.6e-117 391.1 12.4 6.6e-117 391.1 12.4 2.1 2 0 0 2 2 2 1 Actin interacting protein 3 Laminin_II PF06009.12 KND98207.1 - 0.064 13.3 6.1 0.063 13.3 2.9 2.6 2 0 0 2 2 2 0 Laminin Domain II CSN5_C PF18323.1 KND98207.1 - 1.4 9.9 0.0 1.4 9.9 0.0 3.7 3 2 0 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain HBM PF16591.5 KND98207.1 - 1.8 8.0 7.9 0.35 10.2 0.1 3.2 2 1 1 3 3 3 0 Helical bimodular sensor domain Baculo_PEP_C PF04513.12 KND98207.1 - 3.1 7.9 13.4 0.11 12.5 1.5 4.0 5 1 0 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF507 PF04368.13 KND98207.1 - 7.1 6.5 10.9 3 7.7 1.6 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF507) Importin_rep_4 PF18808.1 KND98208.1 - 5.4e-27 93.9 10.5 1.2e-26 92.8 0.6 4.6 4 1 1 5 5 4 1 Importin repeat Importin_rep_6 PF18829.1 KND98208.1 - 1.3e-25 89.7 4.7 1.3e-25 89.7 4.7 3.2 3 0 0 3 3 2 1 Importin repeat 6 HEAT_EZ PF13513.6 KND98208.1 - 4.6e-14 52.5 12.2 4.4e-07 30.3 0.2 7.3 6 2 2 8 8 7 3 HEAT-like repeat HEAT_2 PF13646.6 KND98208.1 - 7.5e-13 48.7 1.9 0.0022 18.4 0.0 6.7 5 1 3 8 8 8 4 HEAT repeats Importin_rep_5 PF18816.1 KND98208.1 - 5.8e-12 45.7 0.2 5.8e-12 45.7 0.2 2.1 2 0 0 2 2 1 1 Importin repeat Arm PF00514.23 KND98208.1 - 5.4e-06 26.3 4.2 0.02 14.9 0.1 5.0 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 KND98208.1 - 1e-05 24.9 21.9 0.0011 18.2 2.9 5.7 5 1 1 6 6 6 3 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 KND98208.1 - 9.2e-05 22.4 4.2 0.31 10.9 0.0 5.6 6 1 2 8 8 8 2 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 KND98208.1 - 0.00033 21.2 0.7 0.56 10.8 0.0 5.4 4 2 1 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KND98208.1 - 0.0012 18.9 0.0 0.0012 18.9 0.0 8.9 13 0 0 13 13 10 1 HEAT repeat ParcG PF10274.9 KND98208.1 - 0.0071 16.5 0.9 1 9.4 0.0 4.1 4 1 1 5 5 5 1 Parkin co-regulated protein RIX1 PF08167.12 KND98208.1 - 0.069 12.9 6.7 0.77 9.5 0.1 4.2 4 1 1 5 5 5 0 rRNA processing/ribosome biogenesis UME PF08064.13 KND98208.1 - 0.86 9.5 6.2 4.7 7.2 0.1 3.8 3 1 0 3 3 3 0 UME (NUC010) domain MMR_HSR1_Xtn PF16897.5 KND98209.1 - 7.4e-39 132.0 0.3 1.9e-38 130.7 0.1 1.8 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KND98209.1 - 1.2e-21 76.5 0.1 2.4e-21 75.6 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KND98209.1 - 1.3e-21 76.8 0.3 5.3e-21 74.8 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KND98209.1 - 9.2e-10 38.3 0.1 2.1e-09 37.1 0.1 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KND98209.1 - 0.004 17.2 0.5 2.3 8.2 0.0 2.5 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 KND98209.1 - 0.0077 15.2 1.0 0.017 14.1 0.3 1.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KND98209.1 - 0.03 14.2 1.8 1.8 8.4 0.1 3.1 2 1 1 3 3 3 0 RsgA GTPase AAA_22 PF13401.6 KND98209.1 - 0.14 12.4 0.0 8.4 6.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 KND98210.1 - 2.1e-33 115.5 0.5 7.5e-33 113.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KND98210.1 - 4.5e-21 74.9 0.0 4.5e-21 74.9 0.0 2.1 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KND98210.1 - 4.4e-12 46.2 0.7 4.6e-08 33.3 0.0 3.2 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KND98210.1 - 5.2e-07 29.7 0.1 1.3e-05 25.3 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KND98210.1 - 1.7e-05 24.6 0.1 5.9e-05 22.9 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Roc PF08477.13 KND98210.1 - 0.00064 19.9 0.0 0.002 18.4 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KND98210.1 - 0.013 15.3 0.0 0.013 15.3 0.0 2.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KND98210.1 - 0.11 12.8 0.4 1 9.7 0.4 2.6 1 1 0 1 1 1 0 AAA domain GRIM-19 PF06212.12 KND98211.1 - 1.5e-20 73.5 0.0 1.8e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 GRIM-19 protein BRD4_CDT PF17105.5 KND98211.1 - 0.088 12.4 4.0 4.2 7.0 0.6 2.3 2 0 0 2 2 2 0 C-terminal domain of bromodomain protein 4 Hydrolase_6 PF13344.6 KND98212.1 - 2.8e-28 98.0 0.0 6.6e-28 96.8 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KND98212.1 - 4e-18 65.3 0.0 7.7e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KND98212.1 - 8.4e-12 45.8 0.0 1.3e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KND98212.1 - 0.00016 21.8 3.5 0.027 14.6 0.0 2.5 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KND98212.1 - 0.04 13.5 0.0 0.46 10.1 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Hpt PF01627.23 KND98213.1 - 3.8e-09 36.7 0.0 4.9e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Hpt domain FbpA PF05833.11 KND98213.1 - 0.0015 17.4 0.2 0.0018 17.2 0.2 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NADPH_Ox PF08414.10 KND98213.1 - 0.041 14.2 0.3 0.098 13.0 0.2 1.6 2 0 0 2 2 2 0 Respiratory burst NADPH oxidase Glyco_transf_22 PF03901.17 KND98214.1 - 8.2e-76 255.9 31.9 1e-75 255.6 31.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PDR_assoc PF08370.11 KND98214.1 - 0.4 10.5 4.9 0.23 11.2 0.2 2.7 2 0 0 2 2 2 0 Plant PDR ABC transporter associated SecE PF00584.20 KND98214.1 - 6.8 6.7 8.3 0.44 10.5 1.1 2.8 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex Adenylsucc_synt PF00709.21 KND98215.1 - 5.6e-178 592.1 0.0 6.4e-178 592.0 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Complex1_LYR_2 PF13233.6 KND98217.1 - 6.9e-15 55.6 9.3 4.5e-14 52.9 9.3 2.0 1 1 0 1 1 1 1 Complex1_LYR-like Blo-t-5 PF11642.8 KND98217.1 - 0.053 13.5 5.8 0.035 14.1 3.6 1.7 1 1 1 2 2 2 0 Mite allergen Blo t 5 Bcr-Abl_Oligo PF09036.10 KND98217.1 - 0.95 9.5 7.2 1.3 9.1 4.8 2.0 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain TetR_C_10 PF16295.5 KND98218.1 - 0.035 14.4 0.2 0.074 13.4 0.2 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain FUN14 PF04930.15 KND98220.1 - 3.1e-08 33.9 0.5 5.9e-08 33.0 0.5 1.4 1 1 0 1 1 1 1 FUN14 family RNA_pol_Rpb1_5 PF04998.17 KND98221.1 - 5.9e-95 317.7 0.1 1.2e-94 316.8 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KND98221.1 - 2.3e-68 229.6 0.2 4.3e-68 228.7 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KND98221.1 - 1.4e-39 135.5 0.0 8.1e-39 133.1 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KND98221.1 - 2.3e-26 92.9 0.1 7.4e-25 87.9 0.0 3.0 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KND98221.1 - 6.3e-22 77.6 1.1 1.9e-21 76.1 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Glycos_transf_4 PF00953.21 KND98222.1 - 7e-30 104.1 16.4 7e-30 104.1 16.4 3.0 3 1 0 3 3 3 1 Glycosyl transferase family 4 DUF202 PF02656.15 KND98222.1 - 0.37 11.3 4.7 2 8.9 0.4 4.1 3 2 0 3 3 3 0 Domain of unknown function (DUF202) WD40 PF00400.32 KND98223.1 - 3.8e-20 71.8 9.0 2.4e-05 25.0 0.7 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND98223.1 - 1.2e-10 41.6 2.4 0.028 14.7 0.0 4.2 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KND98223.1 - 0.0032 16.5 0.1 1.9 7.4 0.0 3.5 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KND98224.1 - 0.021 15.7 0.0 0.4 11.6 0.0 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat Cue1_U7BR PF18499.1 KND98225.1 - 0.087 12.9 0.1 0.15 12.1 0.1 1.5 1 1 0 1 1 1 0 Ubc7p-binding region of Cue1 HSP70 PF00012.20 KND98226.1 - 4.1e-69 233.3 2.9 6.6e-69 232.7 1.3 1.8 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KND98226.1 - 9e-06 24.7 0.0 1.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein RabGAP-TBC PF00566.18 KND98227.1 - 1.6e-48 165.2 3.2 1.6e-47 161.9 3.2 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain THF_DHG_CYH PF00763.23 KND98228.1 - 5.8e-25 87.8 0.0 1.2e-24 86.8 0.0 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KND98228.1 - 6.6e-18 64.5 0.0 1.1e-11 44.3 0.0 2.7 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 KND98228.1 - 0.019 15.4 0.0 0.038 14.4 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KND98228.1 - 0.085 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Biopterin_H PF00351.21 KND98229.1 - 0.13 11.3 0.0 0.16 11.0 0.0 1.0 1 0 0 1 1 1 0 Biopterin-dependent aromatic amino acid hydroxylase Myb_DNA-bind_6 PF13921.6 KND98230.1 - 4.9e-32 110.0 9.8 1.3e-13 51.0 1.7 3.9 3 1 1 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KND98230.1 - 7.2e-31 106.1 23.7 7.9e-14 51.6 0.9 4.1 4 0 0 4 4 4 3 Myb-like DNA-binding domain SLIDE PF09111.10 KND98230.1 - 1e-06 28.7 0.7 0.15 12.1 0.2 3.4 1 1 2 3 3 3 3 SLIDE MADF_DNA_bdg PF10545.9 KND98230.1 - 0.0016 18.8 8.7 1.3 9.4 0.1 3.7 1 1 2 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like SANT_DAMP1_like PF16282.5 KND98230.1 - 0.46 10.7 4.0 4.9 7.4 0.1 3.5 3 1 0 4 4 4 0 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 KND98230.1 - 1.3 9.1 7.4 3.7 7.7 0.7 3.2 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain UCH PF00443.29 KND98232.1 - 1.2e-46 159.3 0.1 2.2e-46 158.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KND98232.1 - 2.1e-11 44.0 0.1 1.5e-10 41.2 0.1 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HoxA13_N PF12284.8 KND98232.1 - 0.015 15.9 6.3 0.015 15.9 6.3 2.1 3 0 0 3 3 3 0 Hox protein A13 N terminal zinc_ribbon_10 PF10058.9 KND98232.1 - 2.1 8.1 4.7 12 5.8 1.5 2.5 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Kin17_mid PF10357.9 KND98233.1 - 7.8e-37 126.0 1.9 1.2e-36 125.3 1.9 1.2 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 KND98233.1 - 1.1e-05 25.6 1.8 2.3e-05 24.6 1.8 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KND98233.1 - 0.00015 22.0 1.7 0.00034 20.9 1.7 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF640 PF04852.12 KND98233.1 - 0.031 14.4 0.8 0.22 11.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF640) zf-C2H2_2 PF12756.7 KND98233.1 - 0.034 14.5 2.9 0.055 13.8 0.2 2.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KND98233.1 - 0.05 14.5 0.5 0.15 13.0 0.5 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KND98233.1 - 0.22 12.0 1.4 0.57 10.7 1.4 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Peptidase_M48 PF01435.18 KND98235.1 - 1.5e-26 93.4 0.0 3.4e-26 92.2 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M48 Yos9_DD PF17880.1 KND98235.1 - 0.0012 19.0 0.4 0.65 10.1 0.0 3.4 3 1 1 4 4 4 1 Yos9 dimerzation domain TMEM51 PF15345.6 KND98236.1 - 0.006 16.5 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Transmembrane protein 51 S_4TM PF18159.1 KND98236.1 - 0.19 11.0 0.0 0.39 10.0 0.0 1.4 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain Coa1 PF08695.10 KND98238.1 - 4.3e-41 139.3 0.0 7.4e-41 138.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Alb1 PF09135.11 KND98240.1 - 7.3e-12 46.1 6.7 7.3e-12 46.1 6.7 2.0 2 1 0 2 2 2 1 Alb1 Calreticulin PF00262.18 KND98241.1 - 1.8e-130 435.1 5.7 2.2e-130 434.8 5.7 1.1 1 0 0 1 1 1 1 Calreticulin family RELT PF12606.8 KND98241.1 - 2 7.5 8.4 4.4 6.4 8.4 1.5 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 Exo_endo_phos PF03372.23 KND98243.1 - 1.8e-12 47.3 0.0 9.5e-12 44.9 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KND98243.1 - 0.0022 17.9 0.1 0.25 11.2 0.1 2.4 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase Sugar_tr PF00083.24 KND98250.1 - 1.5e-37 129.5 18.4 2.1e-37 129.1 18.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND98250.1 - 1.3e-32 113.1 22.9 1.3e-32 113.1 22.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRAPPC10 PF12584.8 KND98253.1 - 1.5e-21 76.7 0.1 3.4e-21 75.6 0.1 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.7 KND98253.1 - 0.058 13.4 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Foie-gras_1 PF11817.8 KND98253.1 - 0.062 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 CUE PF02845.16 KND98257.1 - 0.00055 19.6 0.0 0.0012 18.5 0.0 1.7 1 0 0 1 1 1 1 CUE domain HIM1 PF08732.10 KND98257.1 - 0.0019 17.8 0.1 0.027 14.0 0.0 2.2 2 0 0 2 2 2 1 HIM1 PABP PF00658.18 KND98257.1 - 0.1 12.8 0.2 0.37 11.0 0.1 2.0 2 0 0 2 2 2 0 Poly-adenylate binding protein, unique domain Pribosyl_synth PF14572.6 KND98258.1 - 2.6e-36 125.4 0.1 4.2e-36 124.7 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KND98258.1 - 7.9e-36 122.5 0.1 4.5e-35 120.1 0.0 2.2 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KND98258.1 - 1.9e-15 56.7 0.3 5.5e-15 55.2 0.1 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Adap_comp_sub PF00928.21 KND98259.1 - 5.8e-70 235.7 0.0 7.1e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KND98259.1 - 0.0041 17.1 0.0 0.021 14.8 0.0 2.0 2 0 0 2 2 2 1 Clathrin adaptor complex small chain PVL_ORF50 PF07768.11 KND98260.1 - 3.1 8.1 10.3 0.067 13.5 2.5 2.1 2 0 0 2 2 2 0 PVL ORF-50-like family ELFV_dehydrog PF00208.21 KND98269.1 - 3.2e-67 226.8 0.1 4.2e-67 226.4 0.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KND98269.1 - 4.2e-14 51.1 0.1 2.4e-08 32.0 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 KND98269.1 - 0.0037 17.1 0.0 0.042 13.7 0.0 2.4 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ABG_transport PF03806.13 KND98270.1 - 0.0071 14.6 0.0 0.0071 14.6 0.0 1.0 1 0 0 1 1 1 1 AbgT putative transporter family PQQ PF01011.21 KND98271.1 - 0.019 14.9 0.1 0.26 11.3 0.1 2.7 2 0 0 2 2 2 0 PQQ enzyme repeat Flavi_glycop_C PF02832.16 KND98271.1 - 0.075 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Flavivirus glycoprotein, immunoglobulin-like domain PQQ_2 PF13360.6 KND98271.1 - 0.095 12.3 0.2 0.46 10.0 0.1 1.9 1 1 1 2 2 2 0 PQQ-like domain WD40 PF00400.32 KND98271.1 - 0.2 12.6 4.7 15 6.6 0.2 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat Tafi-CsgC PF10610.9 KND98276.1 - 0.12 12.6 0.1 0.13 12.4 0.1 1.0 1 0 0 1 1 1 0 Thin aggregative fimbriae synthesis protein Frataxin_Cyay PF01491.16 KND98277.1 - 2.2e-36 124.2 0.0 2.7e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain PTR2 PF00854.21 KND98279.1 - 1.5e-94 317.1 12.6 1.5e-93 313.8 12.6 2.0 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 KND98279.1 - 2.5e-05 23.4 24.4 0.00019 20.5 4.6 3.1 2 1 2 4 4 4 2 Major Facilitator Superfamily ATP13 PF12921.7 KND98281.1 - 0.00033 20.5 0.1 0.73 9.7 0.0 2.9 3 0 0 3 3 3 2 Mitochondrial ATPase expression PPR_2 PF13041.6 KND98281.1 - 0.0055 16.9 0.2 2.6 8.3 0.0 3.2 3 0 0 3 3 3 2 PPR repeat family PPR_1 PF12854.7 KND98281.1 - 0.0085 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 PPR repeat MRP-S25 PF13741.6 KND98282.1 - 2.8e-83 279.0 4.8 3.3e-83 278.8 4.8 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 KND98282.1 - 0.0012 19.1 1.8 0.16 12.2 0.5 2.9 1 1 1 2 2 2 1 Mitochondrial ribosomal protein S23 CdiI_N PF18228.1 KND98282.1 - 0.066 13.0 1.4 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 CdiI N-terminal domain NDUF_B12 PF08122.12 KND98283.1 - 1.2e-21 76.5 0.1 1.2e-21 76.4 0.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Potass_KdpF PF09604.10 KND98283.1 - 0.66 10.0 3.1 0.91 9.6 3.1 1.2 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) DUF1771 PF08590.10 KND98286.1 - 3.8e-19 68.8 12.5 7.3e-19 67.9 12.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 KND98286.1 - 1.7e-11 44.3 2.5 2.3e-11 43.9 0.2 2.3 2 1 1 3 3 3 1 Smr domain Peptidase_M3_N PF08439.10 KND98286.1 - 0.0076 16.5 1.6 0.02 15.1 1.6 1.8 1 1 0 1 1 1 1 Oligopeptidase F T3SSipB PF16535.5 KND98286.1 - 0.04 14.4 2.4 0.04 14.4 2.4 2.1 1 1 1 2 2 2 0 Type III cell invasion protein SipB Seryl_tRNA_N PF02403.22 KND98286.1 - 0.054 13.7 5.6 0.1 12.8 5.6 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Cep57_MT_bd PF06657.13 KND98286.1 - 0.25 11.8 5.9 0.53 10.8 5.9 1.5 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF2203 PF09969.9 KND98286.1 - 0.27 11.9 4.0 1.3 9.8 4.0 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) YtxH PF12732.7 KND98286.1 - 4.2 8.0 5.5 8.4 7.0 5.5 1.6 1 1 0 1 1 1 0 YtxH-like protein Ras PF00071.22 KND98287.1 - 2.9e-52 176.5 0.1 3.6e-52 176.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND98287.1 - 9.4e-34 116.2 0.1 1.4e-33 115.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND98287.1 - 1.8e-14 53.6 0.1 2.2e-14 53.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KND98287.1 - 9.7e-07 28.4 0.1 1.2e-06 28.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KND98287.1 - 1.3e-06 28.5 0.0 1.9e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KND98287.1 - 3.5e-06 26.7 0.1 9.6e-05 22.0 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KND98287.1 - 6e-06 26.3 0.2 0.013 15.4 0.2 2.5 1 1 2 3 3 3 2 RsgA GTPase ATP_bind_1 PF03029.17 KND98287.1 - 6.2e-05 22.9 0.2 0.0059 16.4 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KND98287.1 - 0.00013 22.4 0.0 0.00019 21.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 KND98287.1 - 0.00044 19.7 0.1 0.00063 19.2 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KND98287.1 - 0.00092 19.5 0.1 0.0076 16.5 0.0 2.3 1 1 1 2 2 2 1 AAA domain PduV-EutP PF10662.9 KND98287.1 - 0.0029 17.3 0.4 0.0077 16.0 0.1 1.9 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 KND98287.1 - 0.0052 16.7 0.0 0.008 16.1 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_7 PF12775.7 KND98287.1 - 0.0083 15.7 0.1 0.014 14.9 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region ATPase_2 PF01637.18 KND98287.1 - 0.0087 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KND98287.1 - 0.0095 15.7 0.1 0.039 13.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain Septin PF00735.18 KND98287.1 - 0.011 15.0 0.2 0.026 13.8 0.2 1.6 1 0 0 1 1 1 0 Septin TniB PF05621.11 KND98287.1 - 0.022 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 KND98287.1 - 0.03 13.5 1.0 0.043 13.0 1.0 1.7 1 1 0 1 1 1 0 G-protein alpha subunit NB-ARC PF00931.22 KND98287.1 - 0.045 12.9 0.1 0.076 12.2 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.14 KND98287.1 - 0.052 13.5 0.1 0.21 11.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 KND98287.1 - 0.061 13.8 0.1 0.12 12.9 0.1 1.5 1 0 0 1 1 1 0 ABC transporter NTPase_1 PF03266.15 KND98287.1 - 0.069 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 NTPase MCM PF00493.23 KND98287.1 - 0.075 12.1 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 MCM P-loop domain cobW PF02492.19 KND98287.1 - 0.079 12.5 0.1 0.16 11.5 0.1 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 KND98287.1 - 0.088 12.8 0.2 0.26 11.3 0.0 1.8 2 1 0 2 2 2 0 AAA domain DAP3 PF10236.9 KND98287.1 - 0.11 11.6 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 RNA_helicase PF00910.22 KND98287.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Retrotran_gag_3 PF14244.6 KND98287.1 - 0.12 12.2 0.1 21 5.0 0.0 2.4 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type RuvB_N PF05496.12 KND98287.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain CBS PF00571.28 KND98288.1 - 8.6e-23 80.5 0.0 6.5e-07 29.7 0.0 4.3 4 0 0 4 4 4 4 CBS domain BH4 PF02180.17 KND98288.1 - 0.18 11.7 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 Bcl-2 homology region 4 FA_desaturase PF00487.24 KND98292.1 - 1.1e-17 64.7 17.2 1.1e-17 64.7 17.2 1.5 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KND98292.1 - 3.4e-13 49.5 0.0 7.2e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Flu_M2 PF00599.17 KND98296.1 - 0.034 14.2 0.1 0.042 13.9 0.1 1.1 1 0 0 1 1 1 0 Influenza Matrix protein (M2) ADH_N PF08240.12 KND98298.1 - 1.9e-29 101.7 0.1 4e-29 100.7 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KND98298.1 - 7.1e-29 100.4 1.3 1.2e-28 99.7 1.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KND98298.1 - 6.9e-06 27.1 0.0 1.4e-05 26.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 KND98298.1 - 0.006 16.3 0.4 0.0096 15.7 0.4 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Epimerase PF01370.21 KND98298.1 - 0.03 13.8 0.1 0.043 13.3 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TFX_C PF14601.6 KND98298.1 - 0.13 12.2 0.1 0.85 9.6 0.0 2.2 2 0 0 2 2 2 0 DNA_binding protein, TFX, C-term Transketolase_N PF00456.21 KND98299.1 - 2.7e-160 532.8 0.0 3.5e-160 532.5 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KND98299.1 - 8e-47 159.2 0.0 1.3e-46 158.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KND98299.1 - 5.9e-10 39.1 0.0 1.9e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KND98299.1 - 8.5e-07 28.5 0.0 4.2e-06 26.2 0.0 1.9 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 KND98299.1 - 4.5e-05 22.6 0.0 7.2e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KND98299.1 - 0.014 15.2 0.2 0.13 12.0 0.2 2.4 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Terpene_synth PF01397.21 KND98299.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain Beta_elim_lyase PF01212.21 KND98299.1 - 0.064 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase BMC PF00936.19 KND98299.1 - 0.083 12.9 0.2 17 5.4 0.0 2.6 2 0 0 2 2 2 0 BMC domain OB_RNB PF08206.11 KND98303.1 - 0.13 11.9 0.5 0.21 11.3 0.1 1.5 2 0 0 2 2 2 0 Ribonuclease B OB domain Not3 PF04065.15 KND98304.1 - 2.3e-74 249.7 20.3 4.4e-74 248.8 20.3 1.5 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KND98304.1 - 1.7e-39 134.9 3.5 4.3e-39 133.6 3.5 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 KND98304.1 - 6.6 7.2 12.4 0.12 12.7 1.9 3.1 1 1 1 2 2 2 0 Syntaxin-like protein LMWPc PF01451.21 KND98305.1 - 2.6e-32 112.2 0.0 2.9e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Med15_fungi PF05397.12 KND98306.1 - 1.8e-25 89.4 2.1 1.8e-25 89.4 2.1 5.9 7 2 0 7 7 7 1 Mediator complex subunit 15 Gal11_ABD1 PF18535.1 KND98306.1 - 6.7e-23 80.6 6.7 6.7e-23 80.6 6.7 6.8 7 1 0 7 7 7 1 Gal11 activator-binding domain (ABD1) KIX_2 PF16987.5 KND98306.1 - 1.6e-16 60.0 3.4 1.7e-16 60.0 0.1 3.0 2 0 0 2 2 2 1 KIX domain EloA-BP1 PF15870.5 KND98306.1 - 0.00041 20.6 3.0 0.00041 20.6 3.0 3.3 4 0 0 4 4 4 1 ElonginA binding-protein 1 KIX PF02172.16 KND98306.1 - 0.0068 16.7 0.9 0.015 15.5 0.1 2.1 2 0 0 2 2 2 1 KIX domain Med15 PF09606.10 KND98306.1 - 0.03 13.0 0.2 0.03 13.0 0.2 4.2 3 1 1 4 4 4 0 ARC105 or Med15 subunit of Mediator complex non-fungal WD40 PF00400.32 KND98307.1 - 6.2e-51 169.3 27.6 1.7e-07 31.8 0.9 11.4 11 0 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND98307.1 - 1.6e-18 66.7 4.6 0.0069 16.7 0.0 8.7 3 2 7 10 10 10 5 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KND98307.1 - 1e-16 61.2 1.1 2.3e-16 60.0 1.1 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.8 KND98307.1 - 4.2e-11 42.2 2.5 0.025 13.3 0.0 5.7 4 2 1 5 5 5 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KND98307.1 - 4.8e-07 29.0 3.5 0.073 12.0 0.2 5.4 3 2 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KND98307.1 - 5.4e-07 29.2 1.7 0.0013 18.2 0.3 4.6 4 1 0 4 4 4 1 WD40-like domain Nucleoporin_N PF08801.11 KND98307.1 - 0.00021 20.2 7.3 1.3 7.7 0.0 5.3 3 2 3 6 6 6 2 Nup133 N terminal like Hira PF07569.11 KND98307.1 - 0.019 14.7 0.0 0.99 9.1 0.0 3.5 3 0 0 3 3 3 0 TUP1-like enhancer of split Methyltransf_FA PF12248.8 KND98307.1 - 0.078 13.3 0.1 13 6.1 0.0 3.5 3 0 0 3 3 3 0 Farnesoic acid 0-methyl transferase Nbas_N PF15492.6 KND98307.1 - 0.088 12.1 0.4 52 3.0 0.0 4.3 3 1 2 6 6 6 0 Neuroblastoma-amplified sequence, N terminal PLA2_B PF01735.18 KND98308.1 - 4.1e-170 566.4 0.0 4.9e-170 566.2 0.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF3172 PF11371.8 KND98308.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) IBR PF01485.21 KND98308.1 - 0.16 12.3 2.5 0.28 11.4 2.5 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Sporozoite_P67 PF05642.11 KND98308.1 - 0.89 7.6 6.5 1.2 7.1 6.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PRR18 PF15671.5 KND98308.1 - 0.99 9.2 6.4 1.6 8.5 6.4 1.3 1 0 0 1 1 1 0 Proline-rich protein family 18 HSP20 PF00011.21 KND98310.1 - 8.8e-05 22.6 10.0 0.07 13.3 0.3 3.8 4 0 0 4 4 4 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KND98310.1 - 0.14 11.8 0.0 0.62 9.7 0.0 2.1 2 0 0 2 2 2 0 HSP20-like domain found in ArsA DUF1635 PF07795.11 KND98310.1 - 7.1 6.4 12.4 30 4.4 12.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) AA_permease PF00324.21 KND98311.1 - 2.1e-81 273.9 48.2 4.9e-80 269.4 48.2 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND98311.1 - 2.6e-27 95.8 37.6 6.9e-27 94.3 37.6 1.7 1 1 0 1 1 1 1 Amino acid permease DpnI_C PF17726.1 KND98311.1 - 2.9 8.1 5.0 0.67 10.1 1.2 2.0 2 0 0 2 2 2 0 Dam-replacing HTH domain Rer1 PF03248.13 KND98311.1 - 3.6 7.3 5.7 4.1 7.1 0.1 2.8 2 0 0 2 2 2 0 Rer1 family DHR-2 PF06920.13 KND98312.1 - 1.1e-45 156.3 1.5 2.4e-45 155.2 0.3 2.1 2 1 0 2 2 2 1 Dock homology region 2 DOCK_N PF16172.5 KND98312.1 - 4.1e-16 58.9 0.0 3.4e-15 55.9 0.0 2.4 1 1 0 1 1 1 1 DOCK N-terminus rve_3 PF13683.6 KND98312.1 - 0.0025 17.5 0.1 4.5 7.1 0.0 3.0 2 0 0 2 2 2 2 Integrase core domain PP-binding PF00550.25 KND98313.1 - 1.5e-11 44.5 0.6 2.1e-11 44.0 0.6 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KND98313.1 - 1.8e-05 24.9 1.4 3.9e-05 23.8 0.9 1.6 1 1 1 2 2 2 1 Acyl-carrier LRR_4 PF12799.7 KND98314.1 - 3.6e-32 109.8 41.9 3.9e-09 36.6 1.5 7.7 3 2 3 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KND98314.1 - 1.7e-21 75.7 32.4 2.9e-05 23.7 2.5 5.8 5 0 0 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 KND98314.1 - 1.4e-15 57.3 20.8 8.4e-07 28.7 2.7 4.8 1 1 5 6 6 6 6 Leucine-rich repeat LRR_6 PF13516.6 KND98314.1 - 8.1e-06 25.5 23.8 0.19 11.9 0.2 8.3 8 1 1 9 9 9 4 Leucine Rich repeat LRR_1 PF00560.33 KND98314.1 - 0.35 11.6 28.6 18 6.4 0.1 8.8 9 3 0 9 9 9 0 Leucine Rich Repeat HSP20 PF00011.21 KND98315.1 - 4.7e-05 23.5 2.1 6.4e-05 23.0 2.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Pih1_fungal_CS PF18482.1 KND98315.1 - 0.0045 17.5 1.3 0.0053 17.2 0.5 1.5 2 0 0 2 2 2 1 Fungal Pih1 CS domain Lipocalin_8 PF16585.5 KND98315.1 - 0.085 13.3 0.2 0.13 12.7 0.2 1.2 1 0 0 1 1 1 0 Lipocalin-like domain ACOX PF01756.19 KND98317.1 - 5.9e-37 127.0 0.0 1e-36 126.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 KND98317.1 - 2e-22 79.2 0.0 3.5e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 KND98317.1 - 1.6e-13 51.3 0.0 3.6e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 KND98317.1 - 0.00047 20.4 0.1 0.01 16.1 0.1 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain IF-2B PF01008.17 KND98318.1 - 6.2e-63 212.6 0.3 2.3e-62 210.8 0.3 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family Gag_p24 PF00607.20 KND98318.1 - 0.1 12.5 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) Med1 PF10744.9 KND98319.1 - 9.3e-40 136.9 3.8 4.2e-38 131.5 3.8 2.7 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Ubie_methyltran PF01209.18 KND98320.1 - 2.3e-87 292.2 0.0 2.7e-87 292.0 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KND98320.1 - 3.5e-13 50.1 0.0 8.9e-13 48.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND98320.1 - 2e-10 41.2 0.0 3.5e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND98320.1 - 6.3e-10 39.0 0.0 4.9e-09 36.2 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND98320.1 - 5.2e-09 36.7 0.0 1.5e-08 35.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND98320.1 - 4.3e-05 23.4 0.0 6.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KND98320.1 - 0.056 13.3 0.0 1.3 8.8 0.0 2.5 3 0 0 3 3 3 0 Hypothetical methyltransferase PK PF00224.21 KND98321.1 - 3.9e-169 562.0 2.1 5.1e-169 561.6 2.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KND98321.1 - 4.4e-38 130.1 0.1 1.4e-37 128.5 0.1 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KND98321.1 - 0.0015 17.7 0.2 0.0036 16.5 0.1 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family DnaJ PF00226.31 KND98322.1 - 6.4e-06 26.2 0.1 1.1e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 KND98322.1 - 0.00022 21.2 0.9 0.00027 20.9 0.9 1.4 1 1 0 1 1 1 1 Pam16 HTH_37 PF13744.6 KND98322.1 - 0.034 14.1 1.7 0.43 10.6 0.1 2.3 1 1 0 2 2 2 0 Helix-turn-helix domain TLV_coat PF00429.19 KND98322.1 - 0.096 11.3 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) AAA PF00004.29 KND98323.1 - 9.9e-57 191.0 0.0 5.3e-43 146.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KND98323.1 - 3.9e-12 45.8 0.3 4.1e-05 23.3 0.0 3.3 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 KND98323.1 - 2.7e-06 27.9 0.0 0.028 14.8 0.0 4.4 4 0 0 4 4 4 1 AAA ATPase domain RuvB_N PF05496.12 KND98323.1 - 4.6e-06 26.5 0.0 0.0014 18.4 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 KND98323.1 - 0.00015 21.7 0.2 0.0035 17.3 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Parvo_NS1 PF01057.17 KND98323.1 - 0.0003 20.0 0.0 0.00057 19.1 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_2 PF07724.14 KND98323.1 - 0.00058 20.0 0.0 0.0059 16.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) TsaE PF02367.17 KND98323.1 - 0.00061 19.8 0.1 0.22 11.6 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KND98323.1 - 0.0026 18.1 0.0 0.018 15.4 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 KND98323.1 - 0.0027 18.0 0.3 0.053 13.8 0.0 3.2 3 1 1 4 4 4 1 AAA domain DUF1280 PF06918.14 KND98323.1 - 0.0063 16.1 0.3 0.028 14.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1280) AAA_7 PF12775.7 KND98323.1 - 0.0064 16.0 0.0 0.031 13.8 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 KND98323.1 - 0.0068 16.6 0.0 0.52 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KND98323.1 - 0.0071 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 KND98323.1 - 0.0083 16.1 0.4 0.069 13.1 0.0 2.9 3 1 0 3 3 1 1 AAA domain (dynein-related subfamily) ATPase PF06745.13 KND98323.1 - 0.0096 15.3 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 1 KaiC TIP49 PF06068.13 KND98323.1 - 0.01 15.0 0.0 0.028 13.6 0.0 1.7 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 KND98323.1 - 0.015 15.3 0.0 0.44 10.6 0.0 2.9 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KND98323.1 - 0.016 14.6 0.0 0.045 13.1 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KND98323.1 - 0.018 14.5 0.0 0.18 11.3 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.6 KND98323.1 - 0.022 15.3 0.3 0.13 12.8 0.0 2.5 3 0 0 3 3 1 0 AAA domain AAA_28 PF13521.6 KND98323.1 - 0.031 14.5 0.0 0.18 12.1 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 KND98323.1 - 0.04 13.8 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KND98323.1 - 0.07 12.7 0.5 0.67 9.5 0.1 2.6 2 1 1 3 3 3 0 AAA domain NACHT PF05729.12 KND98323.1 - 0.073 13.0 0.0 3.3 7.6 0.0 2.7 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 KND98323.1 - 0.075 12.2 0.0 3.8 6.6 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain AAA_11 PF13086.6 KND98323.1 - 0.094 12.5 0.0 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KND98323.1 - 0.12 12.1 0.0 0.57 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain TerD PF02342.18 KND98323.1 - 0.13 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 TerD domain Ribosomal_L31e PF01198.19 KND98324.1 - 9.1e-16 57.9 0.2 1.1e-15 57.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e APC_N_CC PF16689.5 KND98326.1 - 0.073 13.2 2.6 3.7 7.7 0.1 3.1 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain Wtap PF17098.5 KND98326.1 - 0.089 12.7 5.2 0.046 13.7 2.8 1.7 1 1 1 2 2 2 0 WTAP/Mum2p family DivIVA PF05103.13 KND98326.1 - 0.1 12.7 6.4 0.14 12.2 2.0 2.5 2 1 0 2 2 2 0 DivIVA protein Vps51 PF08700.11 KND98326.1 - 0.11 12.5 5.9 0.092 12.8 1.5 2.5 2 1 0 2 2 2 0 Vps51/Vps67 UPF0147 PF03685.13 KND98326.1 - 0.21 11.7 3.9 0.84 9.7 0.6 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0147) HIP1_clath_bdg PF16515.5 KND98326.1 - 0.25 12.0 7.8 0.08 13.6 3.3 2.0 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ThiD2 PF17792.1 KND98326.1 - 0.41 11.1 5.1 0.31 11.5 0.7 2.1 2 0 0 2 2 2 0 ThiD2 family DUF724 PF05266.14 KND98326.1 - 0.56 10.0 4.7 0.16 11.8 2.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 KND98326.1 - 0.67 9.2 4.5 1.1 8.5 4.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4600 PF15372.6 KND98326.1 - 0.81 10.1 7.9 0.15 12.5 4.5 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) XhlA PF10779.9 KND98326.1 - 1.7 8.9 6.9 0.92 9.8 1.0 2.5 1 1 1 2 2 2 0 Haemolysin XhlA LMBR1 PF04791.16 KND98326.1 - 2 7.2 3.3 2.4 7.0 3.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4050 PF13259.6 KND98327.1 - 1.7e-16 61.1 3.6 5.2e-12 46.5 0.2 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF4050) Rxt3 PF08642.10 KND98328.1 - 5.5e-22 78.9 0.1 5.5e-22 78.9 0.1 4.1 3 2 1 4 4 4 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 KND98328.1 - 0.078 13.1 0.0 3 8.0 0.0 2.4 2 0 0 2 2 2 0 LCCL domain Spore_YtfJ PF09579.10 KND98328.1 - 0.094 12.9 0.0 0.24 11.6 0.0 1.6 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) EMP24_GP25L PF01105.24 KND98328.1 - 0.094 12.6 0.3 0.17 11.8 0.3 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Vps39_1 PF10366.9 KND98329.1 - 2.3e-30 105.1 1.2 2.3e-30 105.1 1.2 3.0 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KND98329.1 - 1.7e-15 57.4 0.0 5.1e-15 55.8 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 KND98329.1 - 0.00056 19.8 0.7 0.0021 18.0 0.7 2.0 1 0 0 1 1 1 1 Region in Clathrin and VPS Utp21 PF04192.12 KND98330.1 - 6.6e-71 238.5 0.4 9.6e-71 238.0 0.4 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 KND98330.1 - 7.7e-16 58.2 0.0 6e-05 23.3 0.0 5.2 4 2 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KND98330.1 - 8.2e-12 45.5 10.7 1.1e-07 32.3 0.3 8.0 9 0 0 9 9 9 1 WD domain, G-beta repeat PQQ_2 PF13360.6 KND98330.1 - 0.0012 18.5 0.0 0.018 14.6 0.0 2.7 3 0 0 3 3 3 1 PQQ-like domain Nup160 PF11715.8 KND98330.1 - 0.0079 14.9 0.1 0.047 12.3 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 eIF2A PF08662.11 KND98330.1 - 0.039 13.8 0.0 1.2 8.9 0.0 2.9 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Dus PF01207.17 KND98331.1 - 4e-46 157.5 0.1 4.9e-44 150.7 0.0 2.8 2 1 0 2 2 2 1 Dihydrouridine synthase (Dus) Bap31 PF05529.12 KND98332.1 - 4.4e-46 156.1 1.2 5.5e-46 155.8 1.2 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KND98332.1 - 9.2e-06 25.6 5.3 1.7e-05 24.7 5.3 1.4 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain Clp1 PF06807.14 KND98332.1 - 0.016 15.6 0.1 0.045 14.2 0.0 1.7 2 0 0 2 2 2 0 Pre-mRNA cleavage complex II protein Clp1 DivIC PF04977.15 KND98332.1 - 0.091 12.5 0.9 0.55 10.0 0.9 2.1 2 0 0 2 2 2 0 Septum formation initiator Spc7 PF08317.11 KND98332.1 - 0.14 11.1 0.1 0.18 10.7 0.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Mem_trans PF03547.18 KND98333.1 - 6.7e-31 107.1 0.0 1.5e-30 105.9 0.0 1.6 1 1 0 1 1 1 1 Membrane transport protein SSrecog PF03531.14 KND98335.1 - 3.4e-33 113.4 3.4 2.7e-29 100.9 0.1 4.2 4 0 0 4 4 4 2 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 KND98335.1 - 2.6e-27 95.1 0.1 1e-25 90.0 0.0 3.0 3 0 0 3 3 3 1 POB3-like N-terminal PH domain Rtt106 PF08512.12 KND98335.1 - 7.8e-27 93.5 0.0 1.1e-24 86.6 0.0 3.5 4 0 0 4 4 4 1 Histone chaperone Rttp106-like Vps39_1 PF10366.9 KND98336.1 - 0.11 12.8 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Semialdhyde_dhC PF02774.18 KND98337.1 - 5.7e-42 143.9 0.0 8.1e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KND98337.1 - 9.1e-31 106.8 0.0 1.6e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 KND98337.1 - 0.0028 18.4 0.0 0.0069 17.1 0.0 1.7 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Sacchrp_dh_NADP PF03435.18 KND98337.1 - 0.027 14.7 0.0 0.066 13.5 0.0 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_16 PF10294.9 KND98338.1 - 4.4e-12 46.1 0.0 3.8e-05 23.5 0.0 2.1 1 1 1 2 2 2 2 Lysine methyltransferase SAC3_GANP PF03399.16 KND98339.1 - 9.9e-108 360.0 0.3 9.9e-108 360.0 0.3 1.7 2 0 0 2 2 2 1 SAC3/GANP family SAC3 PF12209.8 KND98339.1 - 1.7e-16 60.1 0.2 5.9e-16 58.4 0.2 2.0 1 0 0 1 1 1 1 Leucine permease transcriptional regulator helical domain SlyX PF04102.12 KND98339.1 - 0.13 12.9 3.8 0.93 10.2 0.2 3.7 2 1 0 2 2 2 0 SlyX ENTH PF01417.20 KND98340.1 - 1e-44 151.6 0.1 1.4e-44 151.1 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KND98340.1 - 0.00091 18.3 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 ANTH domain EspB PF05802.11 KND98340.1 - 0.076 13.0 0.8 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Enterobacterial EspB protein DUF5102 PF17104.5 KND98340.1 - 0.076 13.0 3.3 0.082 12.9 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) VHS PF00790.19 KND98340.1 - 0.086 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 VHS domain Pro_isomerase PF00160.21 KND98341.1 - 8.4e-48 162.6 0.0 1e-47 162.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SNRNP27 PF08648.12 KND98343.1 - 0.0018 18.3 0.2 0.0056 16.7 0.2 1.9 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins zf-C2H2 PF00096.26 KND98343.1 - 0.0021 18.4 0.1 0.004 17.5 0.1 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KND98343.1 - 0.0029 17.8 0.0 0.0051 17.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KND98343.1 - 0.0049 17.2 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KND98343.1 - 0.019 15.3 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 KND98343.1 - 0.036 14.4 0.0 0.068 13.5 0.0 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KND98343.1 - 0.047 14.5 0.0 0.1 13.5 0.0 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KND98343.1 - 0.053 13.4 0.1 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Ntox4 PF15541.6 KND98343.1 - 0.082 13.3 0.0 0.18 12.2 0.0 1.6 1 1 0 1 1 1 0 Bacterial toxin 4 TPX2 PF06886.11 KND98343.1 - 0.25 11.6 22.1 0.25 11.6 13.0 2.5 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) PNK3P PF08645.11 KND98344.1 - 1.9e-43 148.0 0.0 2.5e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase HAD_2 PF13419.6 KND98344.1 - 0.26 11.3 2.3 13 5.9 0.0 2.8 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase ADK PF00406.22 KND98345.1 - 0.0065 16.6 0.1 0.011 15.9 0.1 1.4 1 1 0 1 1 1 1 Adenylate kinase Ribosomal_S8 PF00410.19 KND98346.1 - 9.8e-06 25.5 0.0 1.9e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein S8 TMEM192 PF14802.6 KND98347.1 - 0.11 11.6 0.2 0.3 10.2 0.2 1.7 1 0 0 1 1 1 0 TMEM192 family Zip PF02535.22 KND98349.1 - 1.2e-70 238.4 1.0 1.4e-70 238.2 1.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter CBS PF00571.28 KND98350.1 - 1.9e-26 92.2 6.3 2.8e-11 43.7 0.1 4.4 4 0 0 4 4 4 4 CBS domain OPT PF03169.15 KND98351.1 - 1.6e-144 482.9 26.4 1.8e-144 482.7 26.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein KH_1 PF00013.29 KND98352.1 - 2.4e-39 133.0 1.2 5.8e-13 48.5 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KND98352.1 - 4.4e-11 42.5 0.8 0.0023 17.7 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KND98352.1 - 9.3e-07 28.6 0.1 0.11 12.3 0.0 3.4 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 KND98352.1 - 0.01 15.9 3.6 6.3 7.0 0.2 3.3 3 0 0 3 3 3 0 NusA-like KH domain KLRAQ PF10205.9 KND98352.1 - 0.011 16.0 2.3 0.021 15.0 2.3 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein BCNT PF07572.12 KND98353.1 - 1.5e-23 82.6 1.9 4.2e-23 81.2 1.9 1.7 1 0 0 1 1 1 1 Bucentaur or craniofacial development Peptidase_M49 PF03571.15 KND98354.1 - 9.1e-227 753.8 0.0 1.2e-226 753.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M49 MogR_DNAbind PF12181.8 KND98354.1 - 0.034 14.1 0.3 0.088 12.7 0.3 1.6 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) RAI1 PF08652.11 KND98354.1 - 0.08 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease EF-hand_3 PF09069.11 KND98354.1 - 0.084 13.3 0.4 7.3 7.1 0.1 3.1 3 0 0 3 3 3 0 EF-hand UPF0228 PF05727.11 KND98354.1 - 0.15 11.9 0.3 0.32 10.8 0.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0228) ABC_membrane PF00664.23 KND98355.1 - 3.2e-48 164.7 4.8 4.3e-48 164.3 4.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KND98355.1 - 2.1e-28 99.6 0.0 7.4e-28 97.8 0.0 2.0 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KND98355.1 - 1.8e-06 27.5 0.0 3.1e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 KND98355.1 - 7.2e-05 23.2 0.1 0.0022 18.4 0.1 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 KND98355.1 - 0.00038 19.4 0.1 0.00073 18.4 0.1 1.4 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 KND98355.1 - 0.0012 19.2 0.0 0.0064 16.9 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KND98355.1 - 0.0019 18.5 0.2 0.044 14.1 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KND98355.1 - 0.015 14.9 0.0 0.047 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF2073 PF09846.9 KND98355.1 - 0.032 14.1 0.1 0.098 12.5 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2073) AAA_18 PF13238.6 KND98355.1 - 0.06 13.9 0.1 3.2 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 KND98355.1 - 0.1 12.4 0.1 0.71 9.6 0.1 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase SbcCD_C PF13558.6 KND98355.1 - 0.18 12.1 0.3 2 8.7 0.3 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 KND98355.1 - 2.2 8.3 12.4 1.8 8.6 0.0 3.8 4 0 0 4 4 4 0 Helicase HerA, central domain ATP-synt_Eps PF04627.13 KND98356.1 - 5.2e-20 71.2 0.3 6.2e-20 70.9 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DNA_pol_phi PF04931.13 KND98357.1 - 8.6e-173 576.4 40.5 1.2e-172 575.9 40.5 1.2 1 0 0 1 1 1 1 DNA polymerase phi GAT PF03127.14 KND98357.1 - 1.4 9.3 8.0 0.16 12.3 0.2 3.3 3 0 0 3 3 3 0 GAT domain PfkB PF00294.24 KND98358.1 - 6.5e-73 245.7 1.1 7.5e-73 245.5 1.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KND98358.1 - 0.036 13.4 0.1 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase TRAM_LAG1_CLN8 PF03798.16 KND98359.1 - 2.5e-38 131.8 23.2 3.7e-38 131.3 23.2 1.3 1 0 0 1 1 1 1 TLC domain Ras PF00071.22 KND98360.1 - 6e-65 217.8 0.5 7.3e-65 217.5 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND98360.1 - 1.1e-36 125.7 0.2 1.8e-36 125.0 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND98360.1 - 1.3e-17 63.8 0.1 1.7e-17 63.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KND98360.1 - 8.5e-07 28.6 0.1 9.5e-07 28.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KND98360.1 - 2.2e-05 24.4 0.5 0.098 12.6 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KND98360.1 - 6.2e-05 23.1 0.0 0.0001 22.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KND98360.1 - 7.5e-05 22.4 0.2 0.00019 21.0 0.2 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KND98360.1 - 0.0014 18.0 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 KND98360.1 - 0.0015 19.0 0.0 0.013 16.0 0.0 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KND98360.1 - 0.0052 17.2 0.0 0.0079 16.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KND98360.1 - 0.013 15.8 0.0 0.041 14.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KND98360.1 - 0.02 14.6 0.2 0.3 10.8 0.2 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation CENP-M PF11111.8 KND98360.1 - 0.024 13.8 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) FeoB_N PF02421.18 KND98360.1 - 0.028 13.9 0.0 0.19 11.2 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 KND98360.1 - 0.038 13.5 0.3 0.077 12.5 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 KND98360.1 - 0.038 14.5 0.0 0.054 14.0 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KND98360.1 - 0.043 13.6 0.0 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 KND98360.1 - 0.046 13.0 0.0 0.1 11.8 0.0 1.6 2 0 0 2 2 2 0 Septin Pam16 PF03656.13 KND98360.1 - 0.058 13.4 0.9 0.36 10.9 0.3 2.2 2 0 0 2 2 2 0 Pam16 AAA_5 PF07728.14 KND98360.1 - 0.071 13.1 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TniB PF05621.11 KND98360.1 - 0.077 12.4 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein DUF3237 PF11578.8 KND98361.1 - 2e-23 82.9 0.0 2.2e-23 82.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Rpn3_C PF08375.11 KND98363.1 - 3.1e-25 88.4 0.9 1e-24 86.7 0.3 2.1 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KND98363.1 - 2.4e-21 76.2 2.2 5.3e-21 75.1 1.0 2.3 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 KND98363.1 - 0.017 15.2 2.5 0.99 9.7 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat SAM_Ste50p PF09235.10 KND98363.1 - 0.051 13.8 0.1 2.7 8.3 0.0 2.9 1 1 1 2 2 2 0 Ste50p, sterile alpha motif CSN8_PSD8_EIF3K PF10075.9 KND98363.1 - 0.085 12.8 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family Med17 PF10156.9 KND98364.1 - 3.7e-106 355.6 11.0 4.7e-106 355.3 11.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Ilm1 PF10311.9 KND98365.1 - 5.4e-14 52.2 7.5 1.3e-10 41.2 7.5 2.1 1 1 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 FAM199X PF15814.5 KND98365.1 - 0.066 12.3 0.0 0.096 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein family FAM199X UAA PF08449.11 KND98365.1 - 0.19 10.9 6.9 0.38 9.9 0.6 2.1 2 0 0 2 2 2 0 UAA transporter family Ribophorin_II PF05817.14 KND98367.1 - 4.3e-09 35.5 1.9 5.6e-09 35.1 1.9 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Peptidase_S24 PF00717.23 KND98368.1 - 0.0029 17.5 0.0 0.013 15.4 0.0 2.2 1 1 1 2 2 2 2 Peptidase S24-like Peptidase_S26 PF10502.9 KND98368.1 - 0.035 13.9 0.0 0.18 11.6 0.0 2.2 1 1 0 1 1 1 0 Signal peptidase, peptidase S26 Med26 PF08711.11 KND98369.1 - 5e-09 36.0 0.0 1.3e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain LSM14 PF12701.7 KND98370.1 - 6.4e-25 87.1 0.0 9.5e-25 86.5 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KND98370.1 - 1.5e-06 29.0 13.9 0.00089 20.1 0.5 3.1 3 1 1 4 4 4 2 FDF domain SM-ATX PF14438.6 KND98370.1 - 0.00012 22.1 0.0 0.00021 21.4 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain FoP_duplication PF13865.6 KND98370.1 - 0.56 10.8 15.3 1.5 9.4 15.3 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 API5 PF05918.11 KND98370.1 - 1.2 7.8 5.2 1.6 7.5 5.2 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Ribosom_S12_S23 PF00164.25 KND98371.1 - 3e-51 171.8 0.2 3.9e-51 171.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Mito_carr PF00153.27 KND98372.1 - 1.1e-52 176.0 3.9 9.7e-19 67.1 1.0 3.9 3 2 0 3 3 3 3 Mitochondrial carrier protein Aldo_ket_red PF00248.21 KND98373.1 - 9.7e-53 179.3 0.3 4.8e-43 147.4 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Hexapep_2 PF14602.6 KND98374.1 - 5.7e-09 35.6 5.6 2.4e-08 33.6 4.6 2.1 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 KND98374.1 - 7.8e-08 31.7 6.0 7.8e-08 31.7 6.0 2.8 3 0 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 KND98374.1 - 2.8e-05 24.3 1.6 7.8e-05 22.8 1.6 1.7 1 1 0 1 1 1 1 Maltose acetyltransferase Yip1 PF04893.17 KND98375.1 - 2.3e-12 47.0 16.6 3.9e-12 46.2 16.6 1.3 1 0 0 1 1 1 1 Yip1 domain Asp PF00026.23 KND98376.1 - 1.1e-40 140.0 4.0 1.6e-40 139.5 4.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KND98376.1 - 0.047 13.5 0.0 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KND98376.1 - 0.048 14.3 0.1 12 6.7 0.0 2.7 2 1 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 KND98376.1 - 0.072 13.7 0.0 6 7.5 0.0 2.9 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_N PF14543.6 KND98376.1 - 0.19 12.0 8.8 0.13 12.5 1.9 2.9 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal DUF4599 PF15371.6 KND98377.1 - 0.11 13.0 0.0 0.13 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4599) Anp1 PF03452.14 KND98378.1 - 6.4e-110 366.7 0.0 7.8e-110 366.4 0.0 1.1 1 0 0 1 1 1 1 Anp1 PGM_PMM_I PF02878.16 KND98380.1 - 1.1e-35 122.4 1.1 8.7e-35 119.4 1.1 2.1 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KND98380.1 - 3.4e-22 79.0 0.0 6.8e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KND98380.1 - 5.9e-15 55.5 0.0 1e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KND98380.1 - 5.2e-06 26.5 0.0 1.5e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Prp19 PF08606.11 KND98381.1 - 6.5e-31 106.1 4.5 2.2e-30 104.5 2.8 2.3 2 0 0 2 2 2 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 KND98381.1 - 4.9e-06 26.8 0.1 0.0013 19.0 0.0 2.9 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 KND98381.1 - 0.0073 16.4 0.1 0.021 15.0 0.0 1.8 2 0 0 2 2 2 1 U-box domain Cytochrom_D1 PF02239.16 KND98381.1 - 0.067 11.7 0.0 0.15 10.6 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain zf-Nse PF11789.8 KND98381.1 - 0.16 11.8 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SUR7 PF06687.12 KND98383.1 - 1.4e-60 204.5 0.0 5.2e-60 202.7 0.0 1.8 1 1 0 1 1 1 1 SUR7/PalI family PMP22_Claudin PF00822.20 KND98383.1 - 0.0077 16.1 3.9 0.017 15.0 3.9 1.6 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family NIF PF03031.18 KND98385.1 - 3.2e-24 85.5 0.0 8.1e-24 84.2 0.0 1.7 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 KND98385.1 - 1.4e-05 25.4 0.0 3.5e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KND98385.1 - 0.021 14.7 2.3 0.044 13.7 0.0 2.8 4 0 0 4 4 4 0 twin BRCT domain BRCT_2 PF16589.5 KND98385.1 - 0.09 13.2 0.1 0.4 11.1 0.0 2.1 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KND98385.1 - 0.11 12.8 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain TAF8_C PF10406.9 KND98387.1 - 4.7e-16 59.1 0.7 4.7e-16 59.1 0.7 2.8 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term CCSAP PF15748.5 KND98387.1 - 0.25 11.5 25.8 0.011 15.9 15.8 2.9 2 1 0 2 2 2 0 Centriole, cilia and spindle-associated ubiquitin PF00240.23 KND98389.1 - 3.3e-19 68.4 0.1 5e-19 67.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KND98389.1 - 4.6e-11 42.4 0.1 7.3e-11 41.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 KND98389.1 - 4e-08 33.0 0.0 9.6e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Ubiquitin_4 PF18036.1 KND98389.1 - 0.0033 17.4 0.3 0.4 10.8 0.1 2.2 1 1 1 2 2 2 1 Ubiquitin-like domain DUF2407 PF10302.9 KND98389.1 - 0.0061 17.1 0.0 0.01 16.4 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.6 KND98389.1 - 0.013 16.0 0.1 0.029 14.8 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KND98389.1 - 0.014 15.4 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like HOIP-UBA PF16678.5 KND98389.1 - 0.028 14.4 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 HOIP UBA domain pair GerD PF17898.1 KND98389.1 - 1 9.3 8.3 1.9 8.5 8.3 1.4 1 0 0 1 1 1 0 Spore germination GerD central core domain DUF1282 PF06930.12 KND98390.1 - 0.0083 15.9 0.1 0.01 15.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) GATA PF00320.27 KND98391.1 - 1.2e-08 34.4 5.5 2.8e-08 33.2 5.5 1.6 1 0 0 1 1 1 1 GATA zinc finger DZR PF12773.7 KND98391.1 - 0.6 10.2 5.9 9.5 6.3 5.9 2.4 1 1 0 1 1 1 0 Double zinc ribbon ADD_DNMT3 PF17980.1 KND98391.1 - 0.83 9.7 5.9 0.22 11.5 2.4 1.8 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 Ribosomal_S4e PF00900.20 KND98397.1 - 3e-37 126.4 1.4 1.1e-36 124.6 0.4 2.1 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 KND98397.1 - 8.3e-24 83.0 0.1 1.7e-23 82.0 0.1 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KND98397.1 - 6.9e-20 70.9 5.9 1.1e-19 70.2 5.4 1.7 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 KND98397.1 - 7.6e-08 32.0 0.0 1.5e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KND98397.1 - 5.7e-05 22.9 4.8 5.7e-05 22.9 4.8 2.7 2 0 0 2 2 2 1 KOW motif Sipho_tail PF05709.11 KND98397.1 - 0.08 12.3 0.0 0.21 10.9 0.1 1.6 1 1 0 1 1 1 0 Phage tail protein DUF4224 PF13986.6 KND98397.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) RabGAP-TBC PF00566.18 KND98399.1 - 2.1e-45 155.0 3.0 2.1e-45 155.0 3.0 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF4201 PF13870.6 KND98399.1 - 0.0013 18.5 3.2 0.0013 18.5 3.2 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4201) Calici_MSP PF05752.11 KND98399.1 - 0.055 13.3 0.6 0.11 12.3 0.6 1.4 1 0 0 1 1 1 0 Calicivirus minor structural protein bZIP_1 PF00170.21 KND98399.1 - 0.13 12.4 14.0 1.4 9.1 0.5 4.2 4 0 0 4 4 4 0 bZIP transcription factor bZIP_2 PF07716.15 KND98399.1 - 2.8 8.1 19.6 3.4 7.8 2.6 4.0 3 1 0 3 3 3 0 Basic region leucine zipper Lectin_N PF03954.14 KND98399.1 - 4.4 7.1 6.5 0.41 10.4 1.0 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Zn_clus PF00172.18 KND98402.1 - 4.9e-08 33.0 18.2 8.9e-08 32.1 18.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KND98402.1 - 4.7e-07 29.9 0.1 1e-06 28.8 0.1 1.6 1 0 0 1 1 1 1 Gal4-like dimerisation domain DUF483 PF04467.12 KND98402.1 - 0.0095 15.9 1.6 0.024 14.6 1.5 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF483) PAS_3 PF08447.12 KND98405.1 - 0.0057 16.9 0.0 0.0071 16.6 0.0 1.1 1 0 0 1 1 1 1 PAS fold RQC PF09382.10 KND98406.1 - 4.1e-26 91.0 0.3 1.6e-25 89.1 0.1 2.0 2 0 0 2 2 2 1 RQC domain Helicase_C PF00271.31 KND98406.1 - 1.6e-22 79.9 0.0 2.4e-17 63.2 0.0 3.0 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 KND98406.1 - 7.2e-22 78.0 0.0 1.5e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KND98406.1 - 9.1e-15 55.1 8.0 9.1e-15 55.1 8.0 2.8 3 0 0 3 3 3 1 RecQ zinc-binding HRDC PF00570.23 KND98406.1 - 1.1e-07 31.8 0.4 6.3e-07 29.3 0.3 2.5 2 0 0 2 2 2 1 HRDC domain Helicase_Sgs1 PF11408.8 KND98406.1 - 1.3e-07 31.6 0.6 3.9e-07 30.0 0.6 1.8 1 0 0 1 1 1 1 Sgs1 RecQ helicase ResIII PF04851.15 KND98406.1 - 0.0035 17.4 0.1 0.015 15.3 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KND98406.1 - 0.018 13.7 0.0 0.03 13.1 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain HipN PF18253.1 KND98406.1 - 0.42 10.3 1.9 3.2 7.5 0.2 2.7 2 0 0 2 2 2 0 Hsp70-interacting protein N N-terminal domain zf-CCCH PF00642.24 KND98410.1 - 3.6e-19 68.2 14.6 2.5e-11 43.2 0.8 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KND98410.1 - 4e-08 33.0 19.1 1.2e-06 28.4 1.0 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KND98410.1 - 6.5e-06 25.8 15.1 0.0028 17.4 0.4 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KND98410.1 - 0.0085 16.5 13.5 0.11 13.0 0.3 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KND98410.1 - 0.2 12.3 16.0 0.04 14.6 2.8 2.9 2 1 1 3 3 3 0 Torus domain SR-25 PF10500.9 KND98410.1 - 1.9 8.1 8.7 1.5 8.4 5.1 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-HIT PF04438.16 KND98411.1 - 0.0028 17.5 17.3 0.0046 16.8 17.3 1.4 1 0 0 1 1 1 1 HIT zinc finger Gcn1_N PF12074.8 KND98412.1 - 1.3e-63 215.4 10.6 3e-62 211.0 0.3 4.8 3 1 1 4 4 4 2 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT_EZ PF13513.6 KND98412.1 - 8.2e-34 115.6 15.8 0.00056 20.4 0.0 15.1 15 1 0 15 15 14 7 HEAT-like repeat HEAT PF02985.22 KND98412.1 - 5.6e-27 91.5 27.2 0.092 13.1 0.0 20.3 22 1 0 22 22 21 4 HEAT repeat HEAT_2 PF13646.6 KND98412.1 - 1.1e-25 89.8 29.7 0.011 16.1 1.1 15.1 11 3 3 15 15 15 7 HEAT repeats CLASP_N PF12348.8 KND98412.1 - 6e-23 81.6 3.7 1.5e-08 34.5 0.0 8.0 8 1 2 10 10 10 3 CLASP N terminal Vac14_Fab1_bd PF12755.7 KND98412.1 - 2.5e-16 60.1 0.1 0.16 12.6 0.0 11.4 10 2 2 13 13 12 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KND98412.1 - 4.3e-09 36.6 25.4 0.011 15.8 1.3 11.2 9 2 4 13 13 13 2 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 KND98412.1 - 9.3e-07 28.9 7.4 0.94 9.4 0.0 8.7 8 3 0 8 8 8 2 Domain of unknown function (DUF3385) Tti2 PF10521.9 KND98412.1 - 0.00038 20.1 0.1 0.25 10.9 0.0 4.2 3 0 0 3 3 3 1 Tti2 family FANCI_S2 PF14676.6 KND98412.1 - 0.00065 20.0 4.0 2.2 8.6 0.3 6.4 5 1 0 5 5 5 1 FANCI solenoid 2 DUF2267 PF10025.9 KND98412.1 - 0.026 14.8 1.1 0.16 12.3 0.2 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) ALF PF03752.13 KND98412.1 - 0.41 10.7 4.4 10 6.2 0.0 4.6 4 0 0 4 4 3 0 Short repeats of unknown function ADSL_C PF10397.9 KND98412.1 - 0.81 10.3 2.6 2.6 8.6 0.0 3.4 4 0 0 4 4 2 0 Adenylosuccinate lyase C-terminus Xpo1 PF08389.12 KND98412.1 - 2 8.5 10.0 24 5.0 0.1 6.6 8 0 0 8 8 7 0 Exportin 1-like protein Cohesin_HEAT PF12765.7 KND98412.1 - 5.7 7.3 15.4 2.4 8.6 0.3 6.3 7 0 0 7 7 6 0 HEAT repeat associated with sister chromatid cohesion R3H-assoc PF13902.6 KND98418.1 - 0.084 13.3 0.4 0.35 11.2 0.1 1.8 2 0 0 2 2 2 0 R3H-associated N-terminal domain RRM_1 PF00076.22 KND98420.1 - 1.9e-26 91.7 1.7 9.7e-13 47.8 0.1 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KND98420.1 - 1.9e-06 27.8 0.1 0.094 12.7 0.0 2.8 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KND98420.1 - 0.00058 19.7 0.0 0.0049 16.7 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 KND98420.1 - 0.0018 18.5 0.0 0.032 14.5 0.1 2.4 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 KND98420.1 - 0.07 13.2 0.2 1 9.5 0.1 2.8 2 1 0 2 2 2 0 RNA recognition motif JAB PF01398.21 KND98421.1 - 1e-31 109.4 0.2 2.5e-31 108.1 0.2 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KND98421.1 - 7.5e-05 22.5 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF2457 PF10446.9 KND98421.1 - 0.0039 16.4 26.8 0.0065 15.7 26.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) UPF0172 PF03665.13 KND98421.1 - 0.027 14.5 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Astro_capsid_p PF12226.8 KND98421.1 - 0.044 13.0 12.6 0.061 12.5 12.6 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 KND98421.1 - 0.19 10.0 16.6 0.3 9.3 16.6 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 KND98421.1 - 0.44 10.6 19.4 0.82 9.7 19.4 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 KND98421.1 - 0.48 8.6 22.7 0.7 8.0 22.7 1.2 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KND98421.1 - 1.4 8.2 19.9 2.5 7.4 19.9 1.5 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.11 KND98421.1 - 2.2 6.3 9.6 3.2 5.7 9.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pes-10 PF07149.11 KND98421.1 - 5.8 5.9 14.7 9.2 5.2 14.7 1.3 1 0 0 1 1 1 0 Pes-10 Rhabdo_ncap PF00945.18 KND98421.1 - 6.5 5.5 7.9 12 4.6 7.6 1.6 2 0 0 2 2 2 0 Rhabdovirus nucleocapsid protein UCH PF00443.29 KND98422.1 - 2.2e-49 168.3 1.5 2.2e-49 168.3 1.5 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KND98422.1 - 1.1e-16 61.3 6.0 8.3e-16 58.5 6.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KND98422.1 - 0.02 14.4 0.4 0.19 11.2 0.5 2.5 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Yippee-Mis18 PF03226.14 KND98423.1 - 1.4e-10 41.3 0.5 2.1e-10 40.7 0.5 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Rsm1 PF08600.10 KND98423.1 - 0.048 13.8 0.2 1 9.6 0.0 2.2 2 0 0 2 2 2 0 Rsm1-like Gin PF10764.9 KND98423.1 - 0.11 12.5 3.4 2.3 8.3 0.2 2.4 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin Eapp_C PF10238.9 KND98423.1 - 0.11 12.5 2.5 0.92 9.6 0.2 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein Ribosomal_L22 PF00237.19 KND98428.1 - 9.6e-19 67.5 0.1 1.4e-18 67.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF1409 PF07197.12 KND98428.1 - 0.025 14.4 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) DUF2147 PF09917.9 KND98428.1 - 0.06 14.0 0.0 0.19 12.4 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2147) SHR3_chaperone PF08229.11 KND98430.1 - 5.9e-68 227.6 0.1 7.6e-68 227.2 0.1 1.2 1 0 0 1 1 1 1 ER membrane protein SH3 BT1 PF03092.16 KND98430.1 - 0.032 12.5 0.0 0.047 11.9 0.0 1.2 1 0 0 1 1 1 0 BT1 family Ras PF00071.22 KND98431.1 - 9.8e-57 191.1 0.0 1.2e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND98431.1 - 2e-20 73.2 0.0 3.7e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND98431.1 - 1.7e-08 34.2 0.0 2.1e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KND98431.1 - 0.1 12.5 0.3 11 5.9 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 KND98431.1 - 0.15 11.6 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region RRM_1 PF00076.22 KND98433.1 - 1e-08 34.9 0.0 2.4e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KND98433.1 - 0.034 14.3 0.0 0.18 11.9 0.0 2.3 1 1 0 1 1 1 0 RNA recognition motif DDHD PF02862.17 KND98433.1 - 1.8 8.7 14.5 2.5 8.2 1.2 2.1 2 0 0 2 2 2 0 DDHD domain RNA_pol_Rpc4 PF05132.14 KND98433.1 - 2.4 8.6 19.6 1.1 9.6 11.6 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 LYRIC PF15686.5 KND98433.1 - 4.5 6.7 29.8 8.1 5.9 29.7 1.4 1 1 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family WD40 PF00400.32 KND98434.1 - 5e-11 43.0 3.6 0.00021 22.0 0.3 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND98434.1 - 2.6e-05 24.4 0.0 0.65 10.3 0.0 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Gluconate_2-dh3 PF13618.6 KND98434.1 - 0.069 13.4 0.3 0.11 12.7 0.3 1.3 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 adh_short PF00106.25 KND98435.1 - 1.2e-11 44.5 0.0 1.9e-09 37.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KND98435.1 - 5e-10 39.6 0.0 8e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KND98435.1 - 5.7e-05 22.8 0.0 0.0003 20.4 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Pkinase PF00069.25 KND98436.1 - 6.4e-51 173.2 0.0 9.2e-51 172.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND98436.1 - 3.6e-25 88.7 0.0 5.9e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KND98436.1 - 0.0089 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KND98436.1 - 0.039 13.6 0.2 1.2 8.8 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KND98436.1 - 0.044 12.7 0.0 0.044 12.7 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Ribosomal_L11_N PF03946.14 KND98437.1 - 7.4e-25 86.6 0.4 1.2e-24 85.9 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KND98437.1 - 1.1e-24 86.7 0.0 1.6e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Mid2 PF04478.12 KND98440.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor WD40 PF00400.32 KND98445.1 - 2.7e-08 34.3 12.7 0.0014 19.4 0.3 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND98445.1 - 0.15 12.4 0.8 11 6.4 0.0 3.6 2 2 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain GDC-P PF02347.16 KND98448.1 - 9e-191 634.3 0.0 5.1e-179 595.6 0.0 2.2 2 0 0 2 2 2 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 KND98448.1 - 5.7e-05 22.2 0.1 0.0043 16.1 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-V Rhabdo_M1 PF03342.13 KND98451.1 - 0.077 12.3 0.1 0.081 12.3 0.1 1.0 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) Arm-DNA-bind_5 PF17293.2 KND98452.1 - 0.0054 17.1 0.2 0.0078 16.6 0.2 1.2 1 0 0 1 1 1 1 Arm DNA-binding domain Gaa1 PF04114.14 KND98452.1 - 0.049 12.7 0.1 0.057 12.4 0.1 1.0 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component Peptidase_M3 PF01432.20 KND98453.1 - 2.8e-104 349.9 0.0 4.4e-104 349.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 MinE PF03776.14 KND98453.1 - 0.05 13.6 0.2 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Septum formation topological specificity factor MinE AA_permease PF00324.21 KND98455.1 - 4e-144 480.8 34.5 4.9e-144 480.5 34.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND98455.1 - 2.4e-41 141.9 37.8 3.3e-41 141.5 37.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3767 PF12597.8 KND98455.1 - 0.24 11.2 0.5 0.74 9.7 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) DUF3671 PF12420.8 KND98455.1 - 0.89 9.7 6.5 12 6.0 0.3 4.0 3 1 0 3 3 3 0 Protein of unknown function Arrestin_N PF00339.29 KND98456.1 - 0.00034 20.7 0.7 0.0014 18.7 0.7 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_N PF00339.29 KND98457.1 - 3.9e-06 27.0 0.2 1.2e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain GRAS PF03514.14 KND98457.1 - 0.065 12.2 0.0 0.093 11.7 0.0 1.1 1 0 0 1 1 1 0 GRAS domain family AF-4 PF05110.13 KND98459.1 - 0.057 11.5 10.0 0.06 11.4 10.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.9 KND98459.1 - 1.5 7.3 6.5 1.5 7.3 6.5 1.0 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 KND98459.1 - 1.9 8.0 12.6 2.9 7.4 12.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC24 PF15669.5 KND98461.1 - 0.23 11.3 2.1 0.27 11.1 2.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family FAM70 PF14967.6 KND98461.1 - 0.62 9.5 5.1 0.68 9.3 5.1 1.1 1 0 0 1 1 1 0 FAM70 protein DUF515 PF04415.12 KND98466.1 - 9.8 4.4 6.1 11 4.3 6.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF4998 PF16389.5 KND98468.1 - 0.052 13.1 1.4 0.07 12.7 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF11 PF01345.18 KND98468.1 - 0.2 12.0 14.9 0.14 12.4 9.8 2.3 2 1 0 2 2 2 0 Domain of unknown function DUF11 GH97_C PF14509.6 KND98468.1 - 0.51 10.6 4.1 0.7 10.2 1.0 2.1 2 0 0 2 2 2 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation Arrestin_N PF00339.29 KND98471.1 - 6.5e-16 58.7 0.9 4.8e-15 55.9 0.9 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Vps26 PF03643.15 KND98471.1 - 0.01 14.9 0.1 0.028 13.4 0.0 1.7 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 26 RTA1 PF04479.13 KND98472.1 - 3.4e-63 213.0 13.6 3.4e-63 213.0 13.6 1.8 2 0 0 2 2 2 1 RTA1 like protein HemY_N PF07219.13 KND98472.1 - 0.12 12.6 0.0 0.12 12.6 0.0 3.6 3 1 1 4 4 4 0 HemY protein N-terminus GWT1 PF06423.12 KND98472.1 - 0.15 12.2 2.5 0.17 12.0 0.7 2.0 2 0 0 2 2 2 0 GWT1 DUF996 PF06195.13 KND98472.1 - 0.57 10.5 18.7 7.5 6.8 0.1 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF996) RTA1 PF04479.13 KND98475.1 - 1.1e-56 191.7 13.7 1.1e-56 191.7 13.7 1.6 2 0 0 2 2 2 1 RTA1 like protein GWT1 PF06423.12 KND98475.1 - 0.082 13.0 0.2 0.082 13.0 0.2 2.1 2 1 0 2 2 2 0 GWT1 DUF898 PF05987.13 KND98475.1 - 0.72 8.8 11.2 0.71 8.9 2.8 2.1 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF898) CRAL_TRIO PF00650.20 KND98478.1 - 1.1e-36 125.9 0.0 3.6e-36 124.3 0.0 1.8 1 1 1 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KND98478.1 - 7.5e-08 32.4 0.0 2.1e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KND98478.1 - 0.00012 22.2 0.0 0.00023 21.3 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1769 PF08588.10 KND98478.1 - 0.027 14.7 0.0 0.068 13.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) DUF3694 PF12473.8 KND98483.1 - 0.084 13.5 0.0 0.085 13.5 0.0 1.0 1 0 0 1 1 1 0 Kinesin protein KH_1 PF00013.29 KND98484.1 - 2.7e-27 94.4 7.6 2.4e-05 24.0 0.1 9.0 8 1 0 8 8 8 6 KH domain FidL_like PF15941.5 KND98484.1 - 0.053 14.0 0.2 0.46 11.0 0.0 2.4 2 0 0 2 2 2 0 FidL-like putative membrane protein p450 PF00067.22 KND98485.1 - 2.4e-54 184.9 0.0 2.8e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Maf_N PF08383.11 KND98485.1 - 0.37 10.6 1.1 5.5 6.9 1.1 2.3 1 1 0 1 1 1 0 Maf N-terminal region TraD_N PF12615.8 KND98488.1 - 0.025 15.3 0.4 0.059 14.1 0.4 1.6 1 0 0 1 1 1 0 F sex factor protein N terminal DUF1195 PF06708.11 KND98488.1 - 0.18 11.5 1.6 3.1 7.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1195) CFEM PF05730.11 KND98490.1 - 0.0014 18.7 1.2 0.004 17.2 1.2 1.8 1 0 0 1 1 1 1 CFEM domain Sporozoite_P67 PF05642.11 KND98490.1 - 0.0065 14.6 8.7 0.0071 14.5 8.7 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Mucin PF01456.17 KND98490.1 - 0.028 14.4 20.4 0.033 14.2 20.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Presenilin PF01080.17 KND98490.1 - 0.23 10.2 3.9 0.29 9.9 3.9 1.0 1 0 0 1 1 1 0 Presenilin SOG2 PF10428.9 KND98490.1 - 0.94 8.6 13.7 1.1 8.4 13.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein NUDE_C PF04880.13 KND98490.1 - 1.4 9.3 13.1 2 8.9 13.1 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Podoplanin PF05808.11 KND98490.1 - 1.6 8.8 9.9 2.2 8.3 9.9 1.3 1 0 0 1 1 1 0 Podoplanin Macoilin PF09726.9 KND98490.1 - 2 6.9 5.8 2 6.9 5.8 1.0 1 0 0 1 1 1 0 Macoilin family Lin-8 PF03353.15 KND98490.1 - 2.1 7.8 5.4 2.4 7.7 5.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GREB1 PF15782.5 KND98490.1 - 2.6 5.1 9.9 2.7 5.0 9.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PP_M1 PF03012.14 KND98490.1 - 3.4 7.1 5.4 4.3 6.8 5.4 1.1 1 0 0 1 1 1 0 Phosphoprotein Apt1 PF10351.9 KND98490.1 - 3.4 6.4 5.4 3.6 6.3 5.4 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hid1 PF12722.7 KND98490.1 - 3.5 5.6 5.3 3.8 5.5 5.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ATF7IP_BD PF16788.5 KND98490.1 - 3.9 7.5 10.3 5.6 7.0 10.3 1.3 1 0 0 1 1 1 0 ATF-interacting protein binding domain Plasmodium_Vir PF05795.11 KND98490.1 - 5.6 6.3 6.0 6.9 6.0 6.0 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein KAR9 PF08580.10 KND98490.1 - 9.2 4.7 10.2 10 4.5 10.2 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 CFEM PF05730.11 KND98494.1 - 5.5e-13 48.8 5.2 9.1e-13 48.1 5.2 1.4 1 0 0 1 1 1 1 CFEM domain Y2_Tnp PF04986.13 KND98498.1 - 0.1 12.6 0.1 0.65 10.0 0.0 1.8 1 1 1 2 2 2 0 Putative transposase Ferric_reduct PF01794.19 KND98499.1 - 9.6e-21 74.2 11.8 9.6e-21 74.2 11.8 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KND98499.1 - 4.5e-15 55.7 0.1 1.4e-14 54.1 0.1 1.9 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KND98499.1 - 5.1e-10 39.7 0.0 8.4e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain SH3_6 PF12913.7 KND98499.1 - 0.071 12.7 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 SH3 domain (SH3b1 type) LapA_dom PF06305.11 KND98499.1 - 0.15 11.9 1.4 0.59 10.0 0.0 2.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Aldo_ket_red PF00248.21 KND98500.1 - 1e-36 126.7 0.1 7.2e-35 120.6 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family GntR PF00392.21 KND98500.1 - 0.0043 16.7 0.0 0.32 10.7 0.0 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Glycos_trans_3N PF02885.17 KND98500.1 - 0.64 9.9 4.2 9.4 6.2 0.0 2.5 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain RTTN_N PF14726.6 KND98501.1 - 0.04 14.7 0.2 0.067 14.0 0.2 1.4 1 0 0 1 1 1 0 Rotatin, an armadillo repeat protein, centriole functioning G_glu_transpept PF01019.21 KND98502.1 - 4.1e-129 431.7 0.0 4.6e-129 431.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Rho_GDI PF02115.17 KND98507.1 - 4.9e-54 183.0 0.2 5.9e-54 182.8 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor UvrD-helicase PF00580.21 KND98508.1 - 3.3e-63 214.1 2.9 5.9e-63 213.3 2.9 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KND98508.1 - 4.5e-55 187.4 0.0 2.4e-27 96.2 0.0 2.9 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KND98508.1 - 7.7e-28 97.7 0.0 2.4e-27 96.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KND98508.1 - 1.3e-11 44.1 0.1 6.8e-11 41.8 0.1 2.2 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_12 PF13087.6 KND98508.1 - 1.2e-05 25.0 0.0 0.017 14.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KND98508.1 - 2.8e-05 23.9 0.3 0.00041 20.1 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KND98508.1 - 2.8e-05 24.0 0.1 5.2e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KND98508.1 - 0.0027 17.5 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Viral_helicase1 PF01443.18 KND98508.1 - 0.0029 17.4 0.1 19 4.9 0.0 3.6 3 1 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KND98508.1 - 0.0091 15.9 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Helicase DUF3410 PF11890.8 KND98508.1 - 0.039 13.8 1.0 0.47 10.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) Lectin_C PF00059.21 KND98509.1 - 0.011 16.4 0.9 0.051 14.3 1.0 2.1 2 0 0 2 2 2 0 Lectin C-type domain Band_7 PF01145.25 KND98510.1 - 8.7e-24 84.5 1.9 1.5e-23 83.7 1.9 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF3416 PF11896.8 KND98510.1 - 0.12 12.6 1.1 0.22 11.8 0.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3416) SH3_9 PF14604.6 KND98511.1 - 2.4e-10 40.1 0.2 4.9e-10 39.1 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KND98511.1 - 5.6e-09 35.5 0.1 1.1e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KND98511.1 - 5.1e-08 32.5 0.0 8.6e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF2076 PF09849.9 KND98511.1 - 0.27 11.3 6.3 0.52 10.3 6.3 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) ALS_ss_C PF10369.9 KND98514.1 - 1.6e-16 60.3 0.2 4.9e-16 58.7 0.0 1.9 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.25 KND98514.1 - 6.4e-11 41.8 0.1 1.2e-10 40.9 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 KND98514.1 - 0.00024 20.9 0.0 0.00041 20.1 0.0 1.4 1 0 0 1 1 1 1 ACT domain Limkain-b1 PF11608.8 KND98514.1 - 0.16 12.0 0.0 0.7 10.0 0.0 2.0 2 0 0 2 2 2 0 Limkain b1 CBFD_NFYB_HMF PF00808.23 KND98519.1 - 8.2e-24 83.7 0.1 1.4e-23 82.9 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KND98519.1 - 0.0011 19.4 1.6 0.0025 18.2 0.1 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KND98519.1 - 0.0023 17.9 0.0 0.0048 16.9 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 KND98519.1 - 0.025 14.7 0.1 0.039 14.1 0.1 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold zf-Tim10_DDP PF02953.15 KND98519.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Tim10/DDP family zinc finger ATP-synt_ab_C PF00306.27 KND98519.1 - 0.071 13.4 0.8 2.7 8.3 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta chain, C terminal domain TFIID_20kDa PF03847.13 KND98519.1 - 0.3 11.6 1.9 1.7 9.2 0.0 2.6 3 0 0 3 3 3 0 Transcription initiation factor TFIID subunit A SH3_1 PF00018.28 KND98520.1 - 1.2e-23 82.4 0.0 2.3e-12 46.3 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KND98520.1 - 4.7e-17 61.6 0.2 3.8e-10 39.4 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 KND98520.1 - 2.1e-11 43.8 0.6 4.4e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 PX domain SH3_2 PF07653.17 KND98520.1 - 2.1e-09 36.9 0.0 7.9e-08 31.9 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain PG_binding_4 PF12229.8 KND98520.1 - 0.12 12.6 0.2 0.35 11.2 0.0 1.9 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Thioredoxin_4 PF13462.6 KND98524.1 - 1.9e-09 37.9 0.0 4.7e-09 36.6 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KND98524.1 - 0.027 14.9 0.1 1.7 9.1 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KND98524.1 - 0.17 12.0 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain Pannexin_like PF12534.8 KND98526.1 - 1.1 8.2 5.8 1.9 7.5 3.4 1.9 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 ABC2_membrane PF01061.24 KND98528.1 - 4.4e-73 245.2 51.0 1.5e-45 155.2 16.5 3.5 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KND98528.1 - 8.9e-39 133.1 0.0 7.6e-19 68.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KND98528.1 - 8.6e-28 96.1 4.6 4.2e-26 90.7 0.1 3.8 4 0 0 4 4 4 2 CDR ABC transporter ABC_trans_N PF14510.6 KND98528.1 - 2e-11 44.3 0.0 4.6e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KND98528.1 - 2.5e-10 40.0 9.9 2.5e-10 40.0 9.9 3.2 2 1 1 3 3 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KND98528.1 - 7.3e-06 26.0 0.1 9.5e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KND98528.1 - 0.00029 21.4 0.0 0.0048 17.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KND98528.1 - 0.00099 19.5 1.1 0.0026 18.2 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KND98528.1 - 0.001 18.9 0.2 0.97 9.2 0.1 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KND98528.1 - 0.0011 18.5 0.0 0.53 9.7 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KND98528.1 - 0.0015 18.3 0.3 0.03 14.1 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KND98528.1 - 0.0042 17.6 0.1 0.018 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KND98528.1 - 0.0053 17.0 0.6 0.021 15.1 0.1 2.4 2 1 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.23 KND98528.1 - 0.0085 16.2 0.1 0.17 12.0 0.1 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KND98528.1 - 0.014 15.5 0.4 0.056 13.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KND98528.1 - 0.019 14.6 0.1 0.049 13.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 KND98528.1 - 0.029 14.0 0.1 0.076 12.6 0.1 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.9 KND98528.1 - 0.029 13.2 0.0 0.055 12.3 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_28 PF13521.6 KND98528.1 - 0.03 14.6 0.6 0.21 11.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KND98528.1 - 0.047 13.7 0.1 0.17 11.9 0.1 1.9 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TrpP PF17099.5 KND98528.1 - 0.055 13.2 2.3 1.1 9.0 0.0 3.5 3 0 0 3 3 3 0 Tryptophan transporter TrpP AAA_17 PF13207.6 KND98528.1 - 0.071 13.5 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KND98528.1 - 0.081 12.7 1.0 1.8 8.3 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 KND98528.1 - 0.12 12.3 0.1 0.35 10.8 0.1 1.8 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 KND98528.1 - 0.28 10.9 0.7 1.2 8.9 0.2 2.0 2 0 0 2 2 2 0 AAA domain Hyphal_reg_CWP PF11765.8 KND98529.1 - 1.2e-59 201.9 5.5 2.3e-59 201.0 5.5 1.5 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal NMT1 PF09084.11 KND98530.1 - 2.1e-78 263.2 0.0 2.6e-78 262.9 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 KND98530.1 - 0.011 15.5 0.0 1.4 8.6 0.0 2.6 3 0 0 3 3 3 0 NMT1-like family MFS_1 PF07690.16 KND98533.1 - 2.5e-30 105.6 25.5 2.5e-30 105.6 25.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KND98533.1 - 0.65 9.7 8.8 0.51 10.0 5.4 2.4 2 1 0 2 2 2 0 Ion channel regulatory protein UNC-93 Mannosyl_trans3 PF11051.8 KND98534.1 - 2.5e-59 200.9 0.0 3.2e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative Nore1-SARAH PF16517.5 KND98534.1 - 0.03 14.2 0.3 0.067 13.1 0.3 1.6 1 0 0 1 1 1 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain ABC_tran PF00005.27 KND98535.1 - 1.2e-07 32.4 0.8 5.1e-07 30.3 0.6 2.2 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KND98535.1 - 0.0002 21.3 0.0 0.00031 20.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KND98535.1 - 0.0036 17.8 4.6 0.0044 17.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KND98535.1 - 0.0075 16.3 0.4 0.059 13.4 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KND98535.1 - 0.0093 16.2 0.5 0.025 14.8 0.1 2.1 2 1 1 3 3 3 1 AAA domain ATPase_2 PF01637.18 KND98535.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 KND98535.1 - 0.025 14.5 0.1 0.08 12.9 0.1 1.7 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 KND98535.1 - 0.042 13.6 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KND98535.1 - 0.046 13.4 0.1 0.21 11.3 0.0 2.0 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 KND98535.1 - 0.049 14.2 0.1 0.094 13.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KND98535.1 - 0.05 13.8 1.0 0.23 11.7 0.8 2.2 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 KND98535.1 - 0.066 12.6 0.0 0.12 11.8 0.0 1.7 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 KND98535.1 - 0.069 13.6 3.0 0.45 11.0 3.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KND98535.1 - 0.1 12.3 0.4 0.18 11.5 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain ATP-synt_ab PF00006.25 KND98535.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 KND98535.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KND98535.1 - 0.22 11.9 3.3 0.72 10.2 3.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain DUF4306 PF14154.6 KND98536.1 - 0.14 12.3 0.0 0.15 12.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) FAD_binding_7 PF03441.14 KND98537.1 - 8.6e-76 253.9 0.1 1.5e-75 253.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KND98537.1 - 1.2e-29 103.5 0.2 2.2e-29 102.6 0.2 1.4 1 0 0 1 1 1 1 DNA photolyase F-box-like PF12937.7 KND98538.1 - 1.8e-05 24.5 0.1 7e-05 22.6 0.1 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KND98538.1 - 0.0028 17.5 1.0 0.019 14.8 0.0 2.7 2 0 0 2 2 2 1 F-box domain zf-C2H2_aberr PF17017.5 KND98542.1 - 0.001 19.3 9.0 0.019 15.1 0.2 2.7 3 0 0 3 3 3 2 Aberrant zinc-finger TFIIA PF03153.13 KND98542.1 - 0.0023 18.0 5.5 0.0025 17.9 5.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit zf-C2H2 PF00096.26 KND98542.1 - 0.0059 17.0 9.4 0.019 15.4 1.0 4.5 6 0 0 6 6 6 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND98542.1 - 0.0077 17.0 5.3 0.033 15.0 0.5 4.4 5 0 0 5 5 5 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KND98542.1 - 0.05 14.1 0.6 0.05 14.1 0.6 3.9 5 0 0 5 5 5 0 Zinc-finger double domain SAG PF04092.13 KND98542.1 - 0.1 13.4 0.1 0.23 12.2 0.1 1.6 1 0 0 1 1 1 0 SRS domain SUIM_assoc PF16619.5 KND98542.1 - 0.66 10.1 11.2 0.059 13.4 4.0 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Seipin PF06775.14 KND98545.1 - 0.0027 17.8 5.4 0.049 13.7 5.4 2.2 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DUF1765 PF08578.10 KND98547.1 - 2.3e-36 125.0 10.5 5e-36 123.9 8.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) Choline_kinase PF01633.20 KND98548.1 - 1.4e-52 178.4 0.0 2.3e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 KND98548.1 - 9e-12 44.5 0.7 6.4e-11 41.8 0.2 2.3 2 0 0 2 2 2 1 Choline kinase N terminus APH PF01636.23 KND98548.1 - 2.5e-06 27.6 0.7 9.2e-06 25.7 0.7 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family WD40 PF00400.32 KND98549.1 - 2.1e-13 50.5 13.4 0.0097 16.7 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat UPF0728 PF15092.6 KND98550.1 - 0.061 13.2 0.1 0.066 13.1 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0728 KH_1 PF00013.29 KND98552.1 - 1.2e-13 50.7 0.0 5.8e-08 32.4 0.1 4.2 4 0 0 4 4 4 3 KH domain Cu2_monoox_C PF03712.15 KND98554.1 - 0.12 11.8 0.5 4 6.9 0.0 2.2 1 1 1 2 2 2 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Sugar_tr PF00083.24 KND98555.1 - 6.7e-99 331.8 18.1 8.3e-99 331.5 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND98555.1 - 2.3e-30 105.7 28.3 4.8e-30 104.7 20.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KND98555.1 - 0.069 11.4 5.5 0.13 10.5 5.5 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4927 PF16279.5 KND98556.1 - 0.11 13.5 0.1 0.25 12.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4927) Ribosomal_L7Ae PF01248.26 KND98558.1 - 6.1e-23 80.4 0.6 1.1e-22 79.6 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family UCR_hinge PF02320.16 KND98559.1 - 6.8e-26 90.3 10.7 1.1e-25 89.6 10.7 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein DUF913 PF06025.12 KND98559.1 - 0.015 14.3 4.9 0.018 14.1 4.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nop14 PF04147.12 KND98559.1 - 0.033 12.4 23.9 0.037 12.3 23.9 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KND98559.1 - 0.18 11.2 23.2 0.2 10.9 23.2 1.1 1 0 0 1 1 1 0 BUD22 SpoIIIAH PF12685.7 KND98559.1 - 0.28 11.0 10.8 0.37 10.6 10.8 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein CDC45 PF02724.14 KND98559.1 - 0.41 8.9 15.0 0.51 8.6 15.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 KND98559.1 - 0.76 8.2 18.0 0.92 8.0 18.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3732 PF12532.8 KND98559.1 - 0.85 9.2 5.2 1 8.9 4.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3732) SAPS PF04499.15 KND98559.1 - 3.7 6.2 9.4 4.2 6.0 9.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2076 PF09849.9 KND98559.1 - 4.9 7.1 12.8 6.9 6.6 12.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SDA1 PF05285.12 KND98559.1 - 5 6.4 29.5 6.5 6.1 29.5 1.1 1 0 0 1 1 1 0 SDA1 RRM_1 PF00076.22 KND98561.1 - 1.2e-22 79.5 10.8 1.4e-13 50.5 0.7 4.2 4 1 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KND98561.1 - 0.0069 16.5 0.0 0.3 11.2 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif Rtf2 PF04641.12 KND98561.1 - 0.1 12.0 10.1 0.17 11.3 10.1 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Limkain-b1 PF11608.8 KND98561.1 - 0.13 12.4 0.1 0.13 12.4 0.1 2.1 3 0 0 3 3 3 0 Limkain b1 BRAP2 PF07576.12 KND98561.1 - 0.17 12.1 0.4 2.9 8.2 0.0 2.3 2 0 0 2 2 2 0 BRCA1-associated protein 2 Ureide_permease PF07168.11 KND98561.1 - 0.33 9.7 6.5 0.52 9.0 6.5 1.2 1 0 0 1 1 1 0 Ureide permease NPR3 PF03666.13 KND98561.1 - 0.4 9.4 4.8 0.47 9.2 4.8 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cellulose_synt PF03552.14 KND98561.1 - 0.46 8.9 1.6 0.59 8.6 1.6 1.1 1 0 0 1 1 1 0 Cellulose synthase FancD2 PF14631.6 KND98561.1 - 1.2 6.4 7.9 1.6 6.0 7.9 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease XRN_M PF17846.1 KND98561.1 - 3.3 6.6 7.9 1.4 7.8 5.9 1.4 2 0 0 2 2 2 0 Xrn1 helical domain Afi1 PF07792.12 KND98561.1 - 9 6.8 11.3 0.7 10.4 5.0 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Ribosomal_L2_C PF03947.18 KND98562.1 - 2.3e-42 144.2 4.5 3.8e-42 143.4 4.5 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KND98562.1 - 9.1e-15 54.4 0.1 2.4e-14 53.0 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain ABC_tran PF00005.27 KND98565.1 - 1.1e-55 187.9 0.0 9.3e-33 113.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KND98565.1 - 1.8e-55 188.5 42.0 1.4e-38 133.1 14.1 4.1 4 1 0 4 4 4 2 ABC transporter transmembrane region AAA_23 PF13476.6 KND98565.1 - 2.9e-09 37.7 6.2 2.3e-05 25.0 0.1 3.4 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 KND98565.1 - 3.4e-07 30.4 0.6 0.0052 16.6 0.0 3.5 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KND98565.1 - 6.7e-07 29.0 5.9 0.016 14.6 3.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KND98565.1 - 8e-07 28.7 0.1 0.0086 15.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KND98565.1 - 3.2e-06 27.2 0.0 0.0053 16.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KND98565.1 - 2.9e-05 24.5 0.1 0.069 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 KND98565.1 - 3e-05 23.9 5.3 0.09 12.5 0.1 3.2 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 KND98565.1 - 4.5e-05 23.5 0.3 0.15 12.1 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KND98565.1 - 0.00012 22.3 0.4 0.79 10.0 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KND98565.1 - 0.00072 19.3 0.1 0.054 13.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KND98565.1 - 0.0016 18.0 0.1 0.41 10.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 KND98565.1 - 0.007 15.7 0.0 0.95 8.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 KND98565.1 - 0.0088 15.8 0.0 2 8.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KND98565.1 - 0.015 14.4 0.0 0.8 8.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA PF00004.29 KND98565.1 - 0.015 15.7 0.2 7.5 7.0 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 KND98565.1 - 0.035 14.3 0.2 14 6.0 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KND98565.1 - 0.038 14.0 0.8 5 7.1 0.1 2.7 2 0 0 2 2 2 0 Dynamin family AAA_27 PF13514.6 KND98565.1 - 0.052 13.1 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 KND98565.1 - 0.097 11.4 0.0 0.36 9.6 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_33 PF13671.6 KND98565.1 - 0.11 12.7 0.0 3.1 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KND98565.1 - 0.15 11.6 0.0 2.3 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KND98565.1 - 0.15 11.4 0.4 12 5.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 KND98565.1 - 0.21 11.2 1.7 1.5 8.4 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 KND98565.1 - 1.4 8.9 5.4 2 8.4 0.1 2.7 3 0 0 3 3 2 0 Helicase HerA, central domain AA_permease_2 PF13520.6 KND98566.1 - 2.4e-65 221.1 35.8 2.9e-65 220.8 35.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KND98566.1 - 3.8e-10 39.0 33.8 5.6e-10 38.4 33.8 1.2 1 0 0 1 1 1 1 Amino acid permease NdhL PF10716.9 KND98566.1 - 4.1 7.4 10.5 1.3 9.1 0.7 3.6 3 0 0 3 3 3 0 NADH dehydrogenase transmembrane subunit Mito_carr PF00153.27 KND98568.1 - 4.1e-58 193.3 4.6 2.1e-23 82.1 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KND98568.1 - 0.0068 15.6 0.6 0.33 10.1 0.0 2.3 2 0 0 2 2 2 2 Gammaproteobacterial serine protease YtxH PF12732.7 KND98568.1 - 0.35 11.4 1.0 1 9.9 1.0 1.8 1 0 0 1 1 1 0 YtxH-like protein TUG-UBL1 PF11470.8 KND98569.1 - 0.056 13.7 0.1 0.076 13.2 0.1 1.2 1 0 0 1 1 1 0 TUG ubiquitin-like domain Peptidase_M22 PF00814.25 KND98570.1 - 1.1e-52 179.4 0.0 2.3e-52 178.4 0.0 1.4 1 1 0 1 1 1 1 Glycoprotease family Nse4_C PF08743.10 KND98571.1 - 4.2e-26 91.0 0.0 1.1e-25 89.7 0.0 1.8 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KND98571.1 - 8.3e-08 32.2 0.2 1.8e-07 31.1 0.2 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Mt_ATP-synt_D PF05873.12 KND98571.1 - 0.14 12.0 1.9 0.16 11.8 0.5 1.7 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Mlh1_C PF16413.5 KND98572.1 - 1.5e-65 221.3 0.2 4e-64 216.6 0.2 2.4 1 1 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KND98572.1 - 3.4e-31 107.4 0.0 5.7e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KND98572.1 - 3.5e-09 36.6 0.0 8.7e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KND98572.1 - 2.1e-06 28.2 0.0 4.4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3346 PF11826.8 KND98572.1 - 0.031 14.0 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3346) CIDE-N PF02017.15 KND98572.1 - 0.15 12.1 0.0 0.81 9.8 0.0 2.2 2 0 0 2 2 2 0 CIDE-N domain TPR_8 PF13181.6 KND98574.1 - 3e-07 30.1 3.0 0.003 17.6 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KND98574.1 - 3e-06 27.6 0.2 3 8.9 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KND98574.1 - 6.5e-05 23.4 0.3 0.4 11.2 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KND98574.1 - 0.0011 18.7 0.1 2.7 8.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KND98574.1 - 0.0017 19.0 0.3 4.2 8.1 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat SPOB_a PF14689.6 KND98574.1 - 0.048 13.4 2.7 2.3 8.0 0.2 3.5 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_7 PF13176.6 KND98574.1 - 0.05 13.6 0.1 18 5.7 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KND98574.1 - 0.056 13.7 3.7 1.5 9.1 0.0 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KND98574.1 - 0.067 13.5 1.4 13 6.2 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KND98574.1 - 0.13 12.4 10.9 1.6 9.0 0.0 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KND98574.1 - 0.54 10.4 6.0 0.93 9.6 0.2 3.7 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 5 SUI1 PF01253.22 KND98575.1 - 2.1e-20 73.0 1.7 2.1e-20 73.0 1.7 1.9 2 1 0 2 2 2 1 Translation initiation factor SUI1 R3H-assoc PF13902.6 KND98575.1 - 0.022 15.2 0.9 0.022 15.2 0.9 1.9 2 0 0 2 2 2 0 R3H-associated N-terminal domain MoCF_biosynth PF00994.24 KND98575.1 - 0.087 12.5 1.5 0.18 11.5 0.5 1.9 1 1 0 2 2 2 0 Probable molybdopterin binding domain DUF1788 PF08747.11 KND98575.1 - 2.9 7.9 5.4 0.62 10.1 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1788) DUF4710 PF15828.5 KND98575.1 - 5.6 7.2 13.2 1.4 9.1 3.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) PI_PP_C PF18365.1 KND98576.1 - 0.014 15.3 0.3 5.3 7.0 0.0 2.8 3 0 0 3 3 3 0 Phosphoinositide phosphatase C-terminal domain TPR_17 PF13431.6 KND98576.1 - 0.043 14.2 0.0 0.13 12.7 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KND98576.1 - 0.13 12.5 0.4 0.35 11.2 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Zn_clus PF00172.18 KND98577.1 - 2.4e-08 34.0 5.7 4.2e-08 33.2 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_16 PF13191.6 KND98579.1 - 2.5e-08 34.5 0.7 7.1e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 KND98579.1 - 2.1e-05 24.5 0.0 2.1e-05 24.5 0.0 2.4 4 0 0 4 4 3 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KND98579.1 - 0.0002 21.4 0.0 0.012 15.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KND98579.1 - 0.0032 17.0 0.0 0.0073 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 KND98579.1 - 0.0059 17.0 0.1 0.018 15.5 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Abi_2 PF07751.11 KND98579.1 - 0.0085 16.4 1.6 0.038 14.3 0.0 2.6 3 0 0 3 3 3 1 Abi-like protein AAA_22 PF13401.6 KND98579.1 - 0.0094 16.2 0.0 0.03 14.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KND98579.1 - 0.012 15.4 2.4 1 9.1 0.2 2.7 3 0 0 3 3 3 0 AAA domain TIP49 PF06068.13 KND98579.1 - 0.023 13.9 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain GLTSCR1 PF15249.6 KND98579.1 - 0.043 14.2 0.1 0.043 14.2 0.1 4.0 5 0 0 5 5 4 0 Conserved region of unknown function on GLTSCR protein NTPase_1 PF03266.15 KND98579.1 - 0.061 13.2 0.1 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 NTPase ATP-synt_ab PF00006.25 KND98579.1 - 0.072 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain CbiA PF01656.23 KND98579.1 - 0.086 12.9 0.0 0.32 11.0 0.0 2.0 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase PF06745.13 KND98579.1 - 0.088 12.1 0.1 0.088 12.1 0.1 2.0 2 0 0 2 2 2 0 KaiC AAA_29 PF13555.6 KND98579.1 - 0.13 12.1 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF5320 PF17253.2 KND98579.1 - 4.8 8.3 10.6 0.48 11.5 1.8 2.9 3 0 0 3 3 2 0 Family of unknown function (DUF5320) HECT PF00632.25 KND98581.1 - 5.9e-82 275.6 0.1 9.1e-82 275.0 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pho88 PF10032.9 KND98581.1 - 0.017 14.4 0.5 0.031 13.5 0.5 1.3 1 0 0 1 1 1 0 Phosphate transport (Pho88) IQ PF00612.27 KND98581.1 - 0.03 14.1 0.1 0.095 12.5 0.1 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF4050 PF13259.6 KND98581.1 - 0.16 12.3 0.3 0.34 11.2 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Hydrolase_6 PF13344.6 KND98583.1 - 1.1e-27 96.1 0.0 2.2e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KND98583.1 - 1.5e-09 37.8 0.0 2.9e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KND98583.1 - 1.7e-06 28.4 0.0 7.2e-06 26.4 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KND98583.1 - 4.4e-06 26.9 0.2 0.12 12.4 0.0 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Arf PF00025.21 KND98584.1 - 0.092 12.2 0.4 0.34 10.3 0.2 1.9 1 1 1 2 2 2 0 ADP-ribosylation factor family Methyltransf_32 PF13679.6 KND98585.1 - 0.031 14.3 0.6 0.046 13.7 0.6 1.2 1 0 0 1 1 1 0 Methyltransferase domain PmrD PF11183.8 KND98585.1 - 0.087 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Polymyxin resistance protein PmrD Rpp20 PF12328.8 KND98586.1 - 7.6e-27 93.9 0.4 1.4e-26 93.1 0.4 1.4 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KND98586.1 - 5.1e-07 29.4 0.2 7.9e-07 28.8 0.2 1.3 1 0 0 1 1 1 1 Alba EF-hand_1 PF00036.32 KND98586.1 - 0.081 12.5 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 EF hand Ribosomal_L24e PF01246.20 KND98589.1 - 1.7e-18 66.6 4.2 1.7e-18 66.6 4.2 2.2 3 0 0 3 3 3 1 Ribosomal protein L24e Astro_capsid_p PF12226.8 KND98589.1 - 0.26 10.4 5.8 0.34 10.0 5.8 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Pam16 PF03656.13 KND98590.1 - 3.9e-07 30.1 0.0 4.8e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 KND98590.1 - 0.00016 21.7 0.0 0.00028 20.9 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain ANTH PF07651.16 KND98592.1 - 4.9e-63 212.7 0.9 4.9e-63 212.7 0.9 2.6 3 0 0 3 3 3 1 ANTH domain ENTH PF01417.20 KND98592.1 - 2.7e-07 30.7 0.1 2.7e-07 30.7 0.1 2.5 3 0 0 3 3 3 1 ENTH domain Glyco_hydro_16 PF00722.21 KND98593.1 - 2.5e-46 157.4 0.3 2.5e-46 157.4 0.3 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Nop14 PF04147.12 KND98593.1 - 2.1 6.4 7.1 3 6.0 7.1 1.1 1 0 0 1 1 1 0 Nop14-like family NPR3 PF03666.13 KND98593.1 - 2.7 6.7 14.7 3.5 6.3 14.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SPX PF03105.19 KND98593.1 - 5 6.9 24.9 7.7 6.3 24.9 1.3 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 KND98593.1 - 7.5 5.6 31.2 11 5.1 31.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Rhodanese PF00581.20 KND98597.1 - 6.8e-11 42.6 0.0 7.9e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain CAMSAP_CC1 PF17095.5 KND98597.1 - 0.017 15.0 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin CTP_transf_like PF01467.26 KND98599.1 - 1.4e-33 116.1 0.0 2.9e-33 115.0 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase-like MMM1 PF10296.9 KND98600.1 - 2.2e-135 451.0 0.0 3.2e-135 450.5 0.0 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 OAD_gamma PF04277.13 KND98600.1 - 0.049 14.2 1.4 0.11 13.2 1.4 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF2718 PF10918.8 KND98600.1 - 0.15 12.5 0.0 0.3 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2718) APH PF01636.23 KND98601.1 - 4.2e-08 33.4 0.0 0.00051 20.0 0.2 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KND98601.1 - 2.6e-07 30.4 0.1 9.8e-07 28.6 0.1 1.9 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 KND98601.1 - 1.1e-06 28.2 0.0 1.9e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KND98601.1 - 4.1e-05 23.1 0.0 5.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WaaY PF06176.11 KND98601.1 - 0.00058 19.6 0.0 0.00086 19.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) EcKinase PF02958.20 KND98601.1 - 0.0096 15.3 0.8 0.016 14.5 0.7 1.4 1 1 0 1 1 1 1 Ecdysteroid kinase Pkinase_Tyr PF07714.17 KND98601.1 - 0.022 14.1 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Choline_kinase PF01633.20 KND98601.1 - 0.14 11.7 0.2 0.24 11.0 0.1 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase CLTH PF10607.9 KND98602.1 - 3.2e-11 43.3 5.0 3.2e-11 43.3 5.0 2.3 3 0 0 3 3 3 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KND98602.1 - 0.0065 16.6 0.1 0.015 15.4 0.1 1.7 1 0 0 1 1 1 1 SPRY domain DHFR_2 PF06442.11 KND98602.1 - 0.023 14.5 0.1 0.059 13.2 0.1 1.6 1 0 0 1 1 1 0 R67 dihydrofolate reductase Ribosomal_L29 PF00831.23 KND98602.1 - 0.11 12.5 2.0 21 5.2 0.1 3.6 3 0 0 3 3 3 0 Ribosomal L29 protein HHH PF00633.23 KND98603.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif SapB_2 PF03489.17 KND98603.1 - 0.074 13.2 0.2 2.2 8.5 0.0 2.4 2 0 0 2 2 2 0 Saposin-like type B, region 2 60KD_IMP PF02096.20 KND98604.1 - 1e-11 45.1 0.3 1.5e-11 44.5 0.3 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein Spt4 PF06093.13 KND98605.1 - 2e-28 98.3 0.0 2.8e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger AAA PF00004.29 KND98606.1 - 3.1e-51 173.3 0.0 2e-42 144.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KND98606.1 - 2.1e-10 40.2 0.0 6e-09 35.6 0.0 2.6 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 KND98606.1 - 5.4e-06 26.9 2.7 0.0001 22.8 0.0 4.0 3 2 1 4 4 4 1 AAA ATPase domain IstB_IS21 PF01695.17 KND98606.1 - 1.3e-05 25.0 0.0 0.00035 20.4 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 KND98606.1 - 1.7e-05 25.0 0.0 7.2e-05 23.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KND98606.1 - 0.00032 21.0 0.6 0.19 12.0 0.2 4.2 3 1 0 3 3 3 1 AAA domain Bromodomain PF00439.25 KND98606.1 - 0.00043 20.3 0.0 0.0015 18.6 0.0 1.9 1 0 0 1 1 1 1 Bromodomain AAA_5 PF07728.14 KND98606.1 - 0.00072 19.6 0.0 0.0042 17.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.6 KND98606.1 - 0.0033 17.5 0.0 0.88 9.7 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 KND98606.1 - 0.009 16.0 0.0 0.028 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KND98606.1 - 0.012 15.3 0.0 1.9 8.1 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KND98606.1 - 0.018 14.1 0.0 0.73 8.9 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 TIP49 PF06068.13 KND98606.1 - 0.02 14.1 0.0 0.084 12.1 0.0 1.9 2 0 0 2 2 2 0 TIP49 P-loop domain Mg_chelatase PF01078.21 KND98606.1 - 0.02 14.3 0.2 0.13 11.6 0.1 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 KND98606.1 - 0.023 15.2 0.0 0.28 11.7 0.0 2.9 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 KND98606.1 - 0.026 14.7 0.0 0.091 12.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KND98606.1 - 0.028 14.8 0.0 0.11 12.9 0.0 2.1 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.15 KND98606.1 - 0.047 13.7 0.0 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RuvB_N PF05496.12 KND98606.1 - 0.058 13.1 0.0 0.28 10.9 0.0 2.2 2 0 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KND98606.1 - 0.061 13.9 1.9 0.17 12.4 0.0 2.8 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 KND98606.1 - 0.077 12.7 0.1 0.87 9.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KND98606.1 - 0.12 11.9 0.0 0.46 10.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 KND98606.1 - 0.13 11.7 0.0 0.7 9.3 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 KND98606.1 - 0.17 11.5 0.0 0.46 10.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KND98606.1 - 0.58 9.9 0.0 0.58 9.9 0.0 3.3 3 1 0 3 3 2 0 AAA domain tRNA-synt_1g PF09334.11 KND98608.1 - 7.8e-85 285.0 2.2 3.8e-83 279.4 2.2 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KND98608.1 - 5.7e-21 74.4 3.8 2.7e-13 49.0 0.0 3.9 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KND98608.1 - 1e-06 28.3 0.9 0.0016 17.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 KND98608.1 - 0.0022 17.9 0.1 0.0059 16.6 0.1 1.7 1 1 1 2 2 2 1 Anticodon-binding domain of tRNA Yip1 PF04893.17 KND98609.1 - 3.2e-10 40.0 11.9 5e-10 39.4 11.9 1.3 1 0 0 1 1 1 1 Yip1 domain DUF2070 PF09843.9 KND98609.1 - 0.1 10.9 9.9 0.12 10.7 9.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) GDPD PF03009.17 KND98610.1 - 1.4e-73 247.8 0.0 4.6e-73 246.1 0.0 1.9 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 KND98610.1 - 1.8e-23 82.9 0.1 1.5e-06 28.7 0.0 4.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) SPX PF03105.19 KND98610.1 - 2.8e-17 63.7 21.6 2.3e-12 47.5 0.3 4.6 3 1 1 4 4 4 3 SPX domain Ank_4 PF13637.6 KND98610.1 - 1.3e-13 51.1 0.4 0.00039 20.9 0.0 4.3 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KND98610.1 - 6.2e-11 42.2 2.2 0.59 10.7 0.0 5.6 4 1 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KND98610.1 - 6.1e-10 38.5 1.5 0.77 10.5 0.0 6.6 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KND98610.1 - 1.7e-08 34.6 0.7 0.093 13.1 0.2 4.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Sec34 PF04136.15 KND98610.1 - 0.56 10.1 4.7 0.94 9.4 0.2 3.0 2 0 0 2 2 2 0 Sec34-like family TIP41 PF04176.13 KND98612.1 - 1.9e-66 222.8 0.0 2.6e-66 222.3 0.0 1.2 1 0 0 1 1 1 1 TIP41-like family Serglycin PF04360.12 KND98612.1 - 0.0059 16.6 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Serglycin Sod_Fe_C PF02777.18 KND98613.1 - 1.4e-16 60.5 0.4 3.2e-14 52.9 0.1 2.6 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Dynamitin PF04912.14 KND98614.1 - 0.0035 16.8 2.0 0.045 13.1 0.4 2.1 2 0 0 2 2 2 2 Dynamitin TPR_2 PF07719.17 KND98616.1 - 1.1e-05 25.2 1.4 0.0096 16.0 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KND98616.1 - 0.006 16.4 0.5 0.15 11.9 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KND98616.1 - 0.012 15.7 1.9 3.9 7.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KND98616.1 - 0.019 15.3 0.0 0.28 11.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat MRP-S27 PF10037.9 KND98616.1 - 0.032 13.1 0.1 0.032 13.1 0.1 1.8 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 TPR_14 PF13428.6 KND98616.1 - 0.049 14.5 0.4 8.4 7.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat CTP_synth_N PF06418.14 KND98617.1 - 5.5e-122 406.2 0.2 9.8e-122 405.4 0.2 1.4 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KND98617.1 - 7.7e-54 182.4 0.0 1.2e-53 181.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KND98617.1 - 3.8e-05 23.6 0.2 0.00029 20.7 0.2 2.4 1 1 0 1 1 1 1 Peptidase C26 DUF4019 PF13211.6 KND98618.1 - 0.11 12.9 0.1 0.14 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4019) ESCRT-II PF05871.12 KND98619.1 - 2.4e-40 138.0 0.1 4.7e-40 137.1 0.0 1.5 2 0 0 2 2 2 1 ESCRT-II complex subunit Rap_GAP PF02145.15 KND98619.1 - 0.038 13.6 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Rap/ran-GAP CARD_2 PF16739.5 KND98619.1 - 0.1 12.6 0.3 0.65 10.0 0.0 2.3 3 0 0 3 3 3 0 Caspase recruitment domain SCA7 PF08313.12 KND98621.1 - 0.0045 16.8 0.4 0.0045 16.8 0.4 1.8 2 0 0 2 2 2 1 SCA7, zinc-binding domain LRR_4 PF12799.7 KND98623.1 - 1.5e-11 44.3 13.2 0.48 10.9 0.1 7.6 6 1 2 8 8 8 6 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KND98623.1 - 2.8e-11 43.1 0.7 6.4e-11 42.0 0.7 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KND98623.1 - 1.4e-06 28.0 1.2 4.9e-06 26.3 1.2 2.0 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KND98623.1 - 0.0006 19.7 0.6 0.0014 18.5 0.0 2.0 2 0 0 2 2 2 1 F-box QLQ PF08880.11 KND98623.1 - 0.0018 18.0 1.4 0.0055 16.4 0.3 2.2 2 0 0 2 2 2 1 QLQ LRR_6 PF13516.6 KND98623.1 - 0.017 15.1 14.5 21 5.5 0.0 8.0 10 0 0 10 10 10 0 Leucine Rich repeat LRR_8 PF13855.6 KND98623.1 - 0.045 13.5 0.5 31 4.4 0.1 4.4 4 1 0 4 4 4 0 Leucine rich repeat PRANC PF09372.10 KND98623.1 - 0.049 14.0 0.9 0.15 12.4 0.0 2.3 3 0 0 3 3 3 0 PRANC domain PUF PF00806.19 KND98624.1 - 6.6e-22 75.9 3.1 5.4e-07 28.9 0.0 6.2 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat Peptidase_S78_2 PF14550.6 KND98624.1 - 0.057 13.5 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Putative phage serine protease XkdF PCI PF01399.27 KND98627.1 - 5.4e-15 55.8 2.2 2.9e-14 53.5 2.2 2.3 1 0 0 1 1 1 1 PCI domain eIF-5_eIF-2B PF01873.17 KND98628.1 - 2.2e-33 114.6 0.0 5e-33 113.4 0.0 1.6 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 KND98628.1 - 2e-22 79.1 0.3 2e-22 79.1 0.3 2.6 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon PH PF00169.29 KND98629.1 - 5e-11 43.1 0.2 1.4e-10 41.6 0.2 1.9 1 0 0 1 1 1 1 PH domain DUF1241 PF06840.11 KND98629.1 - 0.088 12.5 0.3 0.32 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1241) PTPlike_phytase PF14566.6 KND98629.1 - 0.74 9.9 5.4 4 7.5 5.4 2.4 1 0 0 1 1 1 0 Inositol hexakisphosphate SUIM_assoc PF16619.5 KND98631.1 - 0.0066 16.5 6.4 0.011 15.8 6.4 1.6 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Recep_L_domain PF01030.24 KND98633.1 - 1.2e-09 38.3 9.0 0.017 15.2 0.9 4.6 1 1 3 4 4 4 4 Receptor L domain LRR_5 PF13306.6 KND98633.1 - 0.087 12.8 11.7 0.27 11.2 4.1 3.1 1 1 2 3 3 3 0 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KND98633.1 - 0.14 11.7 0.6 0.27 10.7 0.6 1.5 1 0 0 1 1 1 0 Leucine-rich repeat LRR_4 PF12799.7 KND98633.1 - 1.1 9.7 24.6 0.16 12.4 3.9 5.9 3 2 3 6 6 6 0 Leucine Rich repeats (2 copies) Macoilin PF09726.9 KND98633.1 - 4.5 5.7 9.8 6.1 5.3 9.8 1.1 1 0 0 1 1 1 0 Macoilin family UDPGP PF01704.18 KND98634.1 - 2.7e-44 151.4 0.0 5.4e-44 150.5 0.0 1.4 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KND98634.1 - 0.027 14.8 0.0 0.051 13.9 0.0 1.7 1 1 0 1 1 1 0 MobA-like NTP transferase domain NTP_transferase PF00483.23 KND98634.1 - 0.032 13.8 0.3 0.21 11.1 0.3 2.2 1 1 0 1 1 1 0 Nucleotidyl transferase DUF1801 PF08818.11 KND98634.1 - 0.063 13.8 0.1 0.27 11.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DU1801) TolA_bind_tri PF16331.5 KND98636.1 - 0.028 14.5 4.8 0.028 14.5 1.7 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation Rx_N PF18052.1 KND98636.1 - 0.27 11.5 2.8 0.26 11.6 0.8 1.9 2 0 0 2 2 2 0 Rx N-terminal domain NPV_P10 PF05531.12 KND98636.1 - 0.43 11.1 5.5 2.6 8.6 0.3 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein kleA_kleC PF17383.2 KND98636.1 - 0.53 10.7 2.6 0.49 10.8 0.5 2.0 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A UPF0242 PF06785.11 KND98636.1 - 1.2 9.2 13.0 0.15 12.1 9.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FliD_N PF02465.18 KND98636.1 - 2 9.2 7.9 15 6.4 1.3 2.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus HAD_2 PF13419.6 KND98641.1 - 1.6e-14 54.4 0.0 2.5e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KND98641.1 - 2.7e-10 40.9 0.0 8.9e-06 26.1 0.0 2.6 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KND98641.1 - 1.2e-06 29.0 0.0 2.1e-06 28.3 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KND98641.1 - 5.8e-05 23.1 0.2 9.9e-05 22.3 0.2 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Phage_attach PF05354.11 KND98641.1 - 0.029 14.3 0.1 0.061 13.2 0.1 1.5 1 0 0 1 1 1 0 Phage Head-Tail Attachment Hydrolase_6 PF13344.6 KND98641.1 - 0.042 14.0 0.1 0.44 10.7 0.1 2.3 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase NUC PF18510.1 KND98641.1 - 0.093 13.2 0.2 11 6.5 0.2 2.2 2 0 0 2 2 2 0 Nuclease domain PITH PF06201.13 KND98645.1 - 9.9e-35 120.0 1.0 1.2e-34 119.7 1.0 1.1 1 0 0 1 1 1 1 PITH domain Holin_SPP1 PF04688.13 KND98646.1 - 0.025 14.8 1.8 0.58 10.4 0.2 2.6 2 0 0 2 2 2 0 SPP1 phage holin His_Phos_1 PF00300.22 KND98647.1 - 2.9e-35 121.7 0.0 6.6e-30 104.3 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Nsp1_C PF05064.13 KND98648.1 - 1.7e-34 118.1 8.3 1.7e-34 118.1 8.3 1.8 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KND98648.1 - 1e-12 48.7 193.1 2.5e-05 25.0 16.8 8.5 1 1 7 8 8 8 5 Nucleoporin FG repeat region Bul1_C PF04426.12 KND98648.1 - 0.024 14.1 0.5 0.052 12.9 0.5 1.6 1 0 0 1 1 1 0 Bul1 C terminus Rota_NSP3 PF01665.16 KND98648.1 - 0.035 13.2 0.6 0.058 12.5 0.6 1.2 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 SesA PF17107.5 KND98648.1 - 0.13 12.4 0.7 0.33 11.2 0.1 1.9 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases FliT PF05400.13 KND98648.1 - 1.4 9.8 4.7 8.1 7.3 0.1 2.6 2 1 0 2 2 2 0 Flagellar protein FliT PQ-loop PF04193.14 KND98649.1 - 5.9e-18 64.4 1.5 4e-11 42.5 0.3 3.5 2 1 0 2 2 2 2 PQ loop repeat ALAD PF00490.21 KND98650.1 - 4.3e-111 371.1 0.0 5.4e-111 370.8 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase DUF3687 PF12459.8 KND98650.1 - 0.057 12.9 3.8 0.11 12.0 3.8 1.5 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein Snf7 PF03357.21 KND98652.1 - 5.2e-30 104.3 13.7 6e-30 104.1 13.7 1.0 1 0 0 1 1 1 1 Snf7 BRE1 PF08647.11 KND98652.1 - 0.024 14.7 4.4 0.024 14.7 4.4 3.1 2 2 1 3 3 3 0 BRE1 E3 ubiquitin ligase Exog_C PF18026.1 KND98652.1 - 0.082 13.0 1.0 0.082 13.0 1.0 2.2 3 0 0 3 3 3 0 Endo/exonuclease (EXOG) C-terminal domain Prominin PF05478.11 KND98652.1 - 0.49 8.3 4.2 0.68 7.8 4.2 1.1 1 0 0 1 1 1 0 Prominin Cas_Cas02710 PF09670.10 KND98652.1 - 0.93 8.2 7.1 0.38 9.5 3.3 1.9 1 1 0 2 2 2 0 CRISPR-associated protein (Cas_Cas02710) Cytochrom_B562 PF07361.11 KND98652.1 - 1.3 9.7 9.8 0.14 12.8 3.1 2.5 2 1 0 3 3 3 0 Cytochrome b562 zf-C4H2 PF10146.9 KND98652.1 - 3.1 8.1 9.6 6.5 7.0 9.4 1.7 1 1 0 1 1 1 0 Zinc finger-containing protein ANAPC4_WD40 PF12894.7 KND98654.1 - 4e-15 55.9 1.5 1.1e-05 25.7 0.1 4.1 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KND98654.1 - 3.4e-13 49.8 7.7 0.00043 21.0 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KND98654.1 - 7.5e-07 28.4 0.0 0.0001 21.4 0.0 2.9 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KND98654.1 - 0.0003 20.7 0.0 0.075 12.9 0.1 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Pkinase PF00069.25 KND98656.1 - 9e-67 225.2 0.0 1.2e-66 224.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND98656.1 - 7e-31 107.5 0.0 1e-30 106.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KND98656.1 - 5.6e-05 22.2 0.1 7.8e-05 21.8 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KND98656.1 - 0.00018 21.5 0.6 0.03 14.3 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KND98656.1 - 0.00065 19.1 0.2 0.003 16.9 0.2 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KND98656.1 - 0.0014 18.0 0.1 0.021 14.2 0.0 2.4 2 1 0 3 3 3 1 Kinase-like RIO1 PF01163.22 KND98656.1 - 0.061 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KND98656.1 - 0.079 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Rgp1 PF08737.10 KND98657.1 - 6.9e-22 78.2 0.5 1.4e-10 41.0 0.0 2.6 2 1 0 2 2 2 2 Rgp1 Mito_carr PF00153.27 KND98661.1 - 5e-69 228.3 1.6 7.6e-23 80.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Scramblase PF03803.15 KND98662.1 - 1.7e-62 210.6 0.0 2.2e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Scramblase Peptidase_C12 PF01088.21 KND98663.1 - 5.2e-39 134.2 0.0 8.6e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KND98663.1 - 2.6e-07 30.4 0.1 7.7e-07 28.9 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Thioredoxin PF00085.20 KND98664.1 - 2e-21 75.9 0.0 1.1e-20 73.6 0.0 2.2 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 KND98664.1 - 2.3e-05 24.8 0.1 0.00016 22.1 0.0 2.3 1 1 2 3 3 3 1 Thioredoxin-like domain TraF PF13728.6 KND98664.1 - 4.5e-05 23.4 0.0 7.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 KND98664.1 - 5.1e-05 23.5 0.0 0.0074 16.6 0.0 2.7 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 KND98664.1 - 5.3e-05 22.7 0.0 0.00012 21.6 0.0 1.5 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KND98664.1 - 0.002 18.1 0.0 0.041 13.8 0.0 2.2 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 KND98664.1 - 0.0097 15.6 0.1 0.018 14.7 0.1 1.4 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 KND98664.1 - 0.14 11.9 0.0 0.64 9.8 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin TMEM82 PF15816.5 KND98664.1 - 0.26 10.2 0.0 0.4 9.6 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 82 FSH1 PF03959.13 KND98665.1 - 1.3e-54 185.1 0.0 9.3e-54 182.3 0.0 1.8 1 1 1 2 2 2 1 Serine hydrolase (FSH1) DLH PF01738.18 KND98665.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.4 1 1 0 1 1 1 0 Dienelactone hydrolase family HAD_2 PF13419.6 KND98666.1 - 0.0015 18.6 1.9 0.0019 18.3 0.9 1.7 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KND98666.1 - 0.012 15.9 0.0 0.11 12.7 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase ATP-synt_E_2 PF08112.11 KND98667.1 - 0.3 11.4 2.1 0.99 9.7 2.1 1.9 1 0 0 1 1 1 0 ATP synthase epsilon subunit Peptidase_M20 PF01546.28 KND98668.1 - 1.7e-32 112.8 0.0 2.6e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KND98668.1 - 2.2e-12 46.9 0.0 3.6e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KND98668.1 - 0.0014 18.4 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 IF4E PF01652.18 KND98669.1 - 1.4e-25 89.9 0.5 2.6e-25 89.1 0.1 1.6 2 0 0 2 2 2 1 Eukaryotic initiation factor 4E Zn_clus PF00172.18 KND98672.1 - 2.6e-05 24.2 7.5 4.5e-05 23.5 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND98672.1 - 0.00088 18.4 5.4 0.0011 18.1 0.3 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain IRF-3 PF10401.9 KND98673.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Interferon-regulatory factor 3 AdoHcyase PF05221.17 KND98674.1 - 1e-129 431.9 0.0 1.9e-74 250.5 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KND98674.1 - 1.3e-82 275.7 3.0 2.1e-82 275.0 3.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KND98674.1 - 7.3e-08 32.0 0.2 4.5e-07 29.4 0.1 2.2 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KND98674.1 - 0.014 14.9 0.2 0.025 14.2 0.2 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KND98674.1 - 0.089 13.1 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain IMS_HHH PF11798.8 KND98675.1 - 0.036 14.4 0.0 0.062 13.6 0.0 1.4 1 0 0 1 1 1 0 IMS family HHH motif Ribonuclease_T2 PF00445.18 KND98676.1 - 1.4e-37 129.7 2.1 2.8e-37 128.7 2.1 1.5 1 0 0 1 1 1 1 Ribonuclease T2 family Adaptin_N PF01602.20 KND98678.1 - 4.8e-72 243.2 1.2 6e-72 242.9 1.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KND98678.1 - 1.6e-11 44.5 0.4 1.1e-10 41.8 0.0 2.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KND98678.1 - 0.0011 19.0 1.9 0.45 10.9 0.1 3.8 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 KND98678.1 - 0.0034 17.7 7.4 0.1 13.0 1.7 4.6 4 1 2 6 6 6 2 HEAT repeats SAPS PF04499.15 KND98678.1 - 0.17 10.6 7.4 0.28 9.9 7.4 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein HEAT_EZ PF13513.6 KND98678.1 - 0.64 10.6 2.6 1.5 9.4 0.1 3.0 3 0 0 3 3 3 0 HEAT-like repeat NOA36 PF06524.12 KND98678.1 - 3.3 6.9 23.7 5.5 6.2 23.7 1.2 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 KND98678.1 - 4.3 6.7 28.5 5.8 6.2 28.5 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KND98678.1 - 5.9 6.1 25.5 8.4 5.6 25.5 1.2 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 KND98678.1 - 7.2 6.1 26.8 12 5.4 26.8 1.3 1 0 0 1 1 1 0 PPP4R2 MPM1 PF17234.2 KND98679.1 - 0.0015 18.8 2.2 0.089 13.0 0.2 2.3 1 1 1 2 2 2 2 Mitochondrial peculiar membrane protein 1 Gal-3-0_sulfotr PF06990.11 KND98679.1 - 0.04 12.8 0.2 0.056 12.3 0.2 1.1 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase Gpi16 PF04113.14 KND98680.1 - 1.4e-188 627.9 0.0 1.6e-188 627.7 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Mad3_BUB1_I PF08311.12 KND98681.1 - 6.3e-43 145.7 0.7 8.9e-43 145.2 0.1 1.6 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 KND98681.1 - 1.2e-07 31.9 0.0 2.1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Mad3_BUB1_II PF08171.11 KND98681.1 - 1.6e-07 31.4 0.0 5e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Pyr_redox_2 PF07992.14 KND98682.1 - 6.4e-28 97.8 0.0 8.6e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KND98682.1 - 1.8e-09 38.0 0.1 1.9e-06 28.3 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KND98682.1 - 4.7e-05 23.4 0.2 0.29 11.1 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 KND98682.1 - 8.2e-05 21.9 0.0 0.00022 20.5 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KND98682.1 - 0.018 14.7 0.0 12 5.4 0.0 2.9 2 1 1 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.17 KND98682.1 - 0.088 12.0 0.0 3.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 KND98682.1 - 0.17 10.9 0.0 0.51 9.3 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein PhoLip_ATPase_C PF16212.5 KND98683.1 - 1.1e-65 221.9 24.9 1.1e-65 221.9 24.9 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KND98683.1 - 3.3e-22 77.9 1.9 3.3e-22 77.9 1.9 3.3 4 0 0 4 4 4 2 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KND98683.1 - 2.1e-14 54.3 0.5 1.5e-06 28.7 0.1 3.5 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KND98683.1 - 6.7e-12 45.3 0.0 4.1e-11 42.8 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KND98683.1 - 1e-09 38.2 0.0 2.7e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KND98683.1 - 0.003 17.3 4.3 0.0042 16.9 1.3 2.8 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KND98683.1 - 0.073 13.1 1.3 0.17 11.9 0.1 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase VTC PF09359.10 KND98684.1 - 7.4e-102 340.4 0.1 7.4e-102 340.4 0.1 2.1 2 1 1 3 3 3 1 VTC domain DUF202 PF02656.15 KND98684.1 - 7e-13 48.8 2.9 2e-12 47.4 2.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 KND98684.1 - 3.6e-11 43.6 22.7 2.2e-07 31.2 1.4 4.0 2 2 1 4 4 4 3 SPX domain ApoLp-III PF07464.11 KND98684.1 - 0.0043 17.2 2.9 0.0043 17.2 2.9 1.9 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) bacHORMA_1 PF18138.1 KND98684.1 - 0.014 15.3 0.7 0.031 14.1 0.1 2.0 2 0 0 2 2 2 0 Bacterial HORMA domain family 1 Syntaxin-6_N PF09177.11 KND98684.1 - 0.052 14.1 0.3 0.052 14.1 0.3 2.7 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.12 KND98684.1 - 0.059 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.13 KND98684.1 - 0.071 12.7 4.1 0.36 10.4 0.8 2.4 2 0 0 2 2 2 0 fzo-like conserved region LXG PF04740.12 KND98684.1 - 0.1 12.3 12.0 0.12 12.0 5.2 3.4 3 1 1 4 4 4 0 LXG domain of WXG superfamily EnY2 PF10163.9 KND98684.1 - 0.12 12.8 1.9 0.17 12.3 0.2 2.2 2 0 0 2 2 2 0 Transcription factor e(y)2 YscO-like PF16789.5 KND98684.1 - 3.5 7.7 11.4 2.1 8.3 2.4 2.6 2 0 0 2 2 2 0 YscO-like protein DAO PF01266.24 KND98687.1 - 8.7e-59 199.9 0.0 9.7e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KND98687.1 - 1.4e-05 25.2 0.0 3.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KND98687.1 - 0.00016 21.0 0.1 0.0011 18.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KND98687.1 - 0.00097 19.6 0.2 0.0066 17.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KND98687.1 - 0.011 15.4 0.1 0.017 14.7 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KND98687.1 - 0.034 14.4 0.0 0.064 13.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_2 PF00890.24 KND98687.1 - 0.055 12.5 0.2 0.081 12.0 0.2 1.4 1 1 0 1 1 1 0 FAD binding domain GMC_oxred_N PF00732.19 KND98687.1 - 0.066 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 GMC oxidoreductase AlaDh_PNT_C PF01262.21 KND98687.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KND98687.1 - 0.11 11.6 0.1 0.46 9.5 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KND98687.1 - 0.2 10.8 2.1 0.16 11.2 0.4 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 KND98688.1 - 8e-70 235.2 0.0 9.1e-70 235.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND98688.1 - 1.3e-29 103.3 0.0 2.3e-29 102.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND98688.1 - 0.00031 20.1 0.0 0.0006 19.2 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KND98688.1 - 0.0022 18.0 0.2 0.0038 17.2 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family SH3_1 PF00018.28 KND98689.1 - 5.1e-08 32.4 0.5 1.1e-07 31.3 0.5 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KND98689.1 - 7.1e-05 22.4 0.2 0.00014 21.5 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KND98689.1 - 0.0053 16.6 0.1 0.012 15.4 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Transglut_core PF01841.19 KND98689.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily Cpn60_TCP1 PF00118.24 KND98691.1 - 1.7e-167 558.0 4.1 2e-167 557.8 4.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RINT1_TIP1 PF04437.13 KND98692.1 - 6.2e-105 351.9 9.5 9.9e-105 351.3 9.5 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Pkinase PF00069.25 KND98694.1 - 3.8e-68 229.7 0.0 4.9e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND98694.1 - 6.5e-32 110.8 0.0 8.1e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KND98694.1 - 3.1e-15 56.3 0.0 7.8e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 FHA domain Pkinase_fungal PF17667.1 KND98694.1 - 5.4e-05 22.2 0.0 8.9e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 KND98694.1 - 9.5e-05 22.6 0.0 0.00022 21.5 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 KND98694.1 - 0.00038 19.9 0.0 0.00058 19.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KND98694.1 - 0.00049 19.5 0.6 6.1 6.1 0.0 3.2 2 1 1 3 3 3 2 Kinase-like FHA_2 PF17913.1 KND98694.1 - 0.0012 19.0 0.0 0.0031 17.7 0.0 1.7 1 0 0 1 1 1 1 FHA domain FTA2 PF13095.6 KND98694.1 - 0.0038 16.9 0.3 0.22 11.1 0.1 2.3 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KND98694.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KND98694.1 - 0.14 11.8 0.2 0.53 9.8 0.2 1.9 1 1 0 1 1 1 0 RIO1 family Sel1 PF08238.12 KND98695.1 - 0.00017 22.2 0.1 23 5.9 0.0 4.8 5 0 0 5 5 5 1 Sel1 repeat TPR_2 PF07719.17 KND98695.1 - 0.00088 19.2 5.1 0.98 9.7 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat GGA_N-GAT PF18308.1 KND98695.1 - 0.0098 15.5 0.1 0.037 13.7 0.1 1.9 1 0 0 1 1 1 1 GGA N-GAT domain TPR_8 PF13181.6 KND98695.1 - 0.029 14.6 4.7 20 5.7 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KND98695.1 - 0.066 13.2 0.4 5.7 7.0 0.0 2.6 2 1 0 2 2 2 0 Putative TPR-like repeat Homeodomain PF00046.29 KND98696.1 - 1.8e-17 62.9 3.1 3.7e-17 61.9 3.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KND98696.1 - 0.0014 18.5 1.3 0.0032 17.3 1.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain Nup54_57_C PF18570.1 KND98696.1 - 0.06 12.9 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain Sigma70_r4_2 PF08281.12 KND98696.1 - 0.2 11.4 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 ATG16 PF08614.11 KND98703.1 - 4.9e-17 62.8 23.9 7.8e-16 58.9 20.7 2.6 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) SlyX PF04102.12 KND98703.1 - 0.0038 17.8 2.1 0.0038 17.8 2.1 3.4 1 1 2 3 3 3 2 SlyX Atg14 PF10186.9 KND98703.1 - 3.2 6.8 9.5 4.4 6.3 9.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 KND98703.1 - 5.7 7.1 10.0 0.6 10.3 4.0 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 KND98703.1 - 8.1 7.0 12.5 1.2e+02 3.2 12.2 2.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 ADH_zinc_N PF00107.26 KND98704.1 - 6.5e-29 100.5 0.9 1e-28 99.9 0.9 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KND98704.1 - 1.3e-28 99.1 0.3 2.8e-28 98.0 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KND98704.1 - 5.5e-06 27.5 0.1 1.4e-05 26.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KND98704.1 - 0.014 14.7 0.5 0.022 14.1 0.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 KND98704.1 - 0.028 13.9 0.1 0.047 13.1 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Glyco_transf_22 PF03901.17 KND98707.1 - 4.8e-84 283.0 27.1 5.6e-84 282.8 27.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Peptidase_C2 PF00648.21 KND98708.1 - 4.8e-07 29.1 0.0 1.1e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KND98708.1 - 1.5e-05 25.3 0.0 0.00028 21.2 0.0 2.6 2 0 0 2 2 2 1 Calpain large subunit, domain III Phage_AlpA PF05930.12 KND98708.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) Alpha-amylase_C PF02806.18 KND98708.1 - 0.14 12.6 0.1 0.73 10.3 0.0 2.2 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain OST3_OST6 PF04756.13 KND98709.1 - 1.8e-87 293.4 1.1 2.2e-87 293.1 1.1 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Peptidase_M56 PF05569.11 KND98709.1 - 0.0056 15.9 1.8 0.0087 15.3 1.8 1.2 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF1240 PF06836.12 KND98709.1 - 0.012 16.1 2.1 0.034 14.7 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) Thioredoxin PF00085.20 KND98709.1 - 0.014 15.4 0.0 0.049 13.6 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin GAPES3 PF17154.4 KND98709.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain Snapin_Pallidin PF14712.6 KND98710.1 - 3e-07 30.8 1.2 3.6e-07 30.5 1.2 1.1 1 0 0 1 1 1 1 Snapin/Pallidin DUF16 PF01519.16 KND98710.1 - 0.00037 20.9 1.3 0.1 13.1 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function DUF16 Seryl_tRNA_N PF02403.22 KND98710.1 - 0.0019 18.4 0.7 0.0021 18.3 0.7 1.1 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain XhlA PF10779.9 KND98710.1 - 0.003 17.7 1.0 1.5 9.1 0.4 2.2 2 0 0 2 2 2 2 Haemolysin XhlA Sipho_Gp157 PF05565.11 KND98710.1 - 0.0067 16.5 0.4 0.0073 16.3 0.4 1.1 1 0 0 1 1 1 1 Siphovirus Gp157 DUF4559 PF15112.6 KND98710.1 - 0.012 15.3 0.3 0.014 15.1 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) SesA PF17107.5 KND98710.1 - 0.019 15.2 0.2 0.022 14.9 0.2 1.1 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Vip3A_N PF12495.8 KND98710.1 - 0.027 14.4 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal DUF4349 PF14257.6 KND98710.1 - 0.03 13.8 0.3 0.033 13.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) SOAR PF16533.5 KND98710.1 - 0.036 14.0 0.8 1.2 9.1 1.1 2.0 1 1 1 2 2 2 0 STIM1 Orai1-activating region NPV_P10 PF05531.12 KND98710.1 - 0.038 14.5 1.5 0.097 13.1 1.0 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2730 PF10805.8 KND98710.1 - 0.044 13.9 1.2 0.11 12.6 1.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF1664 PF07889.12 KND98710.1 - 0.046 13.8 0.6 0.055 13.5 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KND98710.1 - 0.12 12.8 1.3 3 8.3 1.9 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF676 PF05057.14 KND98711.1 - 2.7e-51 174.2 0.0 4.9e-51 173.3 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 KND98711.1 - 0.00075 19.4 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Palm_thioest PF02089.15 KND98711.1 - 0.0028 17.5 0.0 0.0047 16.8 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase LCAT PF02450.15 KND98711.1 - 0.031 13.5 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 KND98711.1 - 0.066 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 KND98711.1 - 0.066 13.8 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND98711.1 - 0.095 12.0 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 RNA_pol_Rpb4 PF03874.16 KND98712.1 - 1.3e-27 96.6 0.5 1.6e-27 96.3 0.5 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 ING PF12998.7 KND98712.1 - 0.1 13.2 1.0 0.84 10.3 0.4 2.2 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding AA_permease PF00324.21 KND98713.1 - 1e-86 291.5 37.1 1.3e-86 291.2 37.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND98713.1 - 5.7e-17 61.7 39.9 7.4e-17 61.3 39.9 1.2 1 0 0 1 1 1 1 Amino acid permease Phage_holin_2_3 PF16080.5 KND98713.1 - 0.4 10.5 2.5 1.1 9.0 0.3 2.7 2 0 0 2 2 2 0 Bacteriophage holin family HP1 S_4TM PF18159.1 KND98713.1 - 2.1 7.6 5.2 1.1 8.5 0.1 2.9 3 0 0 3 3 3 0 SMODS-associating 4TM effector domain GCD14 PF08704.10 KND98714.1 - 3.1e-06 27.1 0.0 0.00077 19.2 0.0 2.3 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 KND98714.1 - 0.044 13.6 0.0 0.23 11.2 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain DEAD PF00270.29 KND98716.1 - 5.7e-47 159.7 0.6 1e-46 158.9 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND98716.1 - 1.4e-23 83.4 0.0 8.5e-23 80.8 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KND98716.1 - 1.1e-17 64.0 0.3 2.5e-17 62.8 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_22 PF13401.6 KND98716.1 - 0.12 12.6 0.8 0.59 10.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain Peptidase_S64 PF08192.11 KND98716.1 - 0.9 8.0 4.3 1.4 7.3 4.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 Sec63 PF02889.16 KND98719.1 - 3.9e-126 419.5 0.9 3.6e-77 259.0 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KND98719.1 - 7.2e-51 172.4 0.9 5.9e-25 88.0 0.6 3.7 5 0 0 5 5 5 2 DEAD/DEAH box helicase ResIII PF04851.15 KND98719.1 - 3.5e-27 95.5 0.0 6.7e-14 52.2 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KND98719.1 - 6.7e-18 65.0 0.0 1.3e-07 31.9 0.0 3.7 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KND98719.1 - 4.4e-08 33.5 0.2 0.0058 16.9 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KND98719.1 - 6.7e-06 26.5 0.3 0.074 13.4 0.5 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KND98719.1 - 3e-05 24.4 1.4 0.13 12.7 0.0 4.2 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KND98719.1 - 0.0058 16.4 0.4 5.8 6.6 0.0 3.5 4 0 0 4 4 4 1 IstB-like ATP binding protein PhoH PF02562.16 KND98719.1 - 0.0062 16.0 0.0 0.39 10.2 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein Helicase_PWI PF18149.1 KND98719.1 - 0.0091 16.2 1.0 0.02 15.1 0.3 2.0 2 0 0 2 2 1 1 N-terminal helicase PWI domain Alba PF01918.21 KND98719.1 - 0.02 14.7 0.0 0.082 12.7 0.0 2.1 2 0 0 2 2 2 0 Alba SpoVIF PF14069.6 KND98719.1 - 0.023 14.5 0.0 0.072 12.9 0.0 1.9 1 0 0 1 1 1 0 Stage VI sporulation protein F TniB PF05621.11 KND98719.1 - 0.15 11.5 1.7 25 4.2 0.1 3.6 3 0 0 3 3 3 0 Bacterial TniB protein Efg1 PF10153.9 KND98720.1 - 2.3e-32 111.7 17.0 2.3e-32 111.7 17.0 1.8 2 0 0 2 2 2 1 rRNA-processing protein Efg1 YfdX PF10938.8 KND98720.1 - 0.046 13.7 8.2 5.3 7.0 0.1 2.5 1 1 1 2 2 2 0 YfdX protein CBP4 PF07960.11 KND98720.1 - 8.8 6.2 14.1 1.5 8.6 0.5 2.8 1 1 1 2 2 2 0 CBP4 MMR_HSR1_Xtn PF16897.5 KND98721.1 - 1.9e-38 130.7 1.9 3.2e-38 130.0 1.0 1.8 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KND98721.1 - 4.4e-20 71.9 0.1 1e-19 70.7 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 KND98721.1 - 8.2e-20 70.6 0.0 2e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KND98721.1 - 3.2e-13 49.5 0.0 6.8e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KND98721.1 - 0.00088 19.4 1.0 0.042 13.9 0.0 2.6 1 1 1 2 2 2 1 Dynamin family Roc PF08477.13 KND98721.1 - 0.021 15.0 0.1 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NAT PF04768.13 KND98721.1 - 0.043 13.5 0.0 0.085 12.5 0.0 1.5 1 1 0 1 1 1 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase AIG1 PF04548.16 KND98721.1 - 0.097 12.0 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 AIG1 family Dynamitin PF04912.14 KND98722.1 - 2.8e-38 132.3 11.7 1.9e-32 113.1 5.6 2.0 1 1 1 2 2 2 2 Dynamitin Fib_alpha PF08702.10 KND98722.1 - 0.00028 21.1 5.7 0.17 12.0 0.3 3.3 2 1 1 3 3 3 2 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 KND98722.1 - 0.0095 16.0 1.5 0.21 11.6 0.1 2.8 1 1 2 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.19 KND98722.1 - 0.07 11.0 5.8 0.25 9.2 0.7 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family LXG PF04740.12 KND98722.1 - 0.083 12.6 7.5 2.8 7.6 1.4 2.9 2 1 1 3 3 3 0 LXG domain of WXG superfamily DUF4795 PF16043.5 KND98722.1 - 0.19 11.3 10.1 1.9 8.1 10.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DASH_Dad3 PF08656.10 KND98722.1 - 0.22 11.7 3.0 0.58 10.3 0.6 2.8 3 0 0 3 3 3 0 DASH complex subunit Dad3 DUF724 PF05266.14 KND98722.1 - 0.22 11.3 16.3 0.21 11.4 1.7 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF724) DUF1515 PF07439.11 KND98722.1 - 0.37 10.8 4.0 9.9 6.2 1.1 3.3 2 2 2 4 4 4 0 Protein of unknown function (DUF1515) Sec5 PF15469.6 KND98722.1 - 0.88 9.3 7.7 0.16 11.7 0.6 2.7 2 1 0 2 2 2 0 Exocyst complex component Sec5 Prominin PF05478.11 KND98722.1 - 1 7.2 5.9 0.98 7.3 1.5 2.3 2 1 1 3 3 3 0 Prominin DUF3867 PF12983.7 KND98722.1 - 1.2 9.2 5.2 0.93 9.5 1.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3867) BLOC1_2 PF10046.9 KND98722.1 - 1.9 8.8 14.1 18 5.7 0.5 4.1 2 1 3 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fzo_mitofusin PF04799.13 KND98722.1 - 2.3 7.8 9.7 1.4 8.5 0.4 3.2 2 2 0 3 3 3 0 fzo-like conserved region Syntaxin-6_N PF09177.11 KND98722.1 - 5.2 7.7 7.0 31 5.2 0.2 3.3 1 1 1 3 3 3 0 Syntaxin 6, N-terminal SlyX PF04102.12 KND98722.1 - 9.7 6.9 14.3 10 6.8 0.7 5.1 3 3 1 5 5 5 0 SlyX Aldedh PF00171.22 KND98723.1 - 1.5e-108 363.3 0.0 1.9e-108 363.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.6 KND98723.1 - 0.03 14.3 0.1 0.072 13.1 0.1 1.6 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated SPEG_u2 PF16650.5 KND98725.1 - 0.024 14.8 0.0 0.035 14.3 0.0 1.2 1 0 0 1 1 1 0 Unstructured region on SPEG complex protein Cas_csx3 PF09620.10 KND98726.1 - 0.0048 16.8 0.1 0.013 15.4 0.1 1.7 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_csx3) NOP19 PF10863.8 KND98730.1 - 1e-18 67.5 4.5 1e-18 67.5 4.5 3.1 1 1 1 2 2 2 1 Nucleolar protein 19 DUF3245 PF11595.8 KND98730.1 - 0.017 15.6 0.1 0.017 15.6 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3245) DUF572 PF04502.13 KND98730.1 - 1.8 8.1 20.7 2.2 7.8 20.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4995 PF16386.5 KND98733.1 - 0.14 12.1 0.1 0.17 11.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function Wbp11 PF09429.10 KND98734.1 - 0.012 16.0 2.2 0.012 16.0 2.2 2.1 2 0 0 2 2 2 0 WW domain binding protein 11 Cryptochrome_C PF12546.8 KND98734.1 - 0.044 14.4 0.2 0.053 14.1 0.2 1.1 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal CDC45 PF02724.14 KND98734.1 - 0.31 9.3 2.2 0.32 9.2 2.2 1.0 1 0 0 1 1 1 0 CDC45-like protein PFK PF00365.20 KND98744.1 - 5.8e-181 600.1 1.2 4.2e-103 344.6 0.7 2.1 2 0 0 2 2 2 2 Phosphofructokinase Pfk_N PF18468.1 KND98744.1 - 4.2e-31 107.3 0.0 9.3e-31 106.2 0.0 1.6 1 0 0 1 1 1 1 Phosphofructokinase N-terminal domain yeast PhoH PF02562.16 KND98744.1 - 0.0055 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DAGK_cat PF00781.24 KND98744.1 - 0.071 12.7 0.2 0.23 11.1 0.1 1.9 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain TgMIC1 PF11476.8 KND98744.1 - 0.13 12.0 1.8 0.35 10.6 0.0 2.3 2 0 0 2 2 2 0 Toxoplasma gondii micronemal protein 1 TgMIC1 Glyco_hydro_16 PF00722.21 KND98747.1 - 2.7e-40 137.7 0.6 3.8e-40 137.2 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SMC_Nse1 PF07574.13 KND98748.1 - 2.7e-19 69.9 0.0 4.6e-14 52.8 0.0 2.1 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KND98748.1 - 9e-09 35.5 7.2 1.4e-08 34.9 7.2 1.3 1 0 0 1 1 1 1 RING-like domain C1_1 PF00130.22 KND98748.1 - 0.00041 20.2 1.4 0.00071 19.4 1.4 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.6 KND98748.1 - 0.055 13.6 2.9 0.1 12.7 2.9 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_2 PF13639.6 KND98748.1 - 0.063 13.6 6.9 0.11 12.8 6.9 1.4 1 0 0 1 1 1 0 Ring finger domain zf-HC5HC2H PF13771.6 KND98748.1 - 0.16 12.3 5.7 0.15 12.3 4.5 1.5 1 1 0 1 1 1 0 PHD-like zinc-binding domain Zf_RING PF16744.5 KND98748.1 - 0.91 9.7 4.5 1.7 8.8 4.5 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 KND98748.1 - 2 8.4 6.7 13 5.8 7.4 1.9 1 1 1 2 2 2 0 PHD-finger SPRY PF00622.28 KND98749.1 - 1.5e-05 25.1 0.0 0.0008 19.5 0.0 2.5 2 0 0 2 2 2 2 SPRY domain DUF1406 PF07190.11 KND98755.1 - 0.0009 19.2 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1406) PhoD PF09423.10 KND98755.1 - 0.0052 15.8 0.4 1.1 8.2 0.0 2.6 2 1 0 2 2 2 2 PhoD-like phosphatase Fungal_trans PF04082.18 KND98756.1 - 1.3e-30 106.4 1.7 7.3e-30 103.9 1.7 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND98756.1 - 2.9e-11 43.3 10.3 2.9e-11 43.3 10.3 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ten1 PF12658.7 KND98757.1 - 2.5e-09 37.1 0.0 2.9e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit DUF4839 PF16127.5 KND98757.1 - 0.13 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4839) DNA_pol_E_B PF04042.16 KND98758.1 - 2.8e-35 121.6 0.0 4.1e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KND98758.1 - 1.1e-29 103.2 0.0 1.7e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain RNB PF00773.19 KND98760.1 - 2.3e-60 204.7 2.7 3.7e-60 204.0 2.7 1.3 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KND98760.1 - 1.5e-23 82.6 0.1 4e-23 81.2 0.0 1.8 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 KND98760.1 - 4.3e-22 78.2 0.1 1.8e-21 76.2 0.0 2.2 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 KND98760.1 - 8.1e-09 35.5 0.1 3.8e-06 27.0 0.0 3.1 3 0 0 3 3 3 1 Cold shock domain OB_RNB PF08206.11 KND98760.1 - 0.0033 17.1 0.1 1.4 8.6 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease B OB domain Rrp44_CSD1 PF17216.3 KND98760.1 - 0.022 14.5 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 KND98760.1 - 0.033 14.1 0.1 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 S1 domain Cas_Csm6 PF09659.10 KND98760.1 - 0.059 12.1 0.2 0.28 9.9 0.0 2.0 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csm6) GTP_cyclohydroI PF01227.22 KND98761.1 - 1.5e-76 255.8 0.5 1.9e-76 255.5 0.5 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KND98761.1 - 5.3e-05 23.3 0.0 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein Amidase PF01425.21 KND98762.1 - 1.6e-106 357.0 0.0 1.9e-106 356.7 0.0 1.0 1 0 0 1 1 1 1 Amidase tRNA-synt_1g PF09334.11 KND98763.1 - 4.2e-159 529.5 1.0 5.4e-159 529.1 1.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KND98763.1 - 5.3e-09 34.9 0.9 0.00012 20.5 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) MetRS-N PF09635.10 KND98763.1 - 5.6e-08 33.4 0.2 1.5e-07 32.0 0.2 1.8 1 1 0 1 1 1 1 MetRS-N binding domain tRNA-synt_1e PF01406.19 KND98763.1 - 0.017 14.5 0.0 0.054 12.8 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain PS_Dcarbxylase PF02666.15 KND98765.1 - 1.8e-54 184.3 0.0 2.9e-54 183.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KND98765.1 - 2e-25 89.1 0.1 1.1e-15 57.8 0.1 2.5 2 0 0 2 2 2 2 C2 domain SRP54 PF00448.22 KND98766.1 - 4.9e-47 160.1 0.9 1.3e-46 158.8 0.9 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain MeaB PF03308.16 KND98766.1 - 4.5e-07 29.1 0.0 1.2e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP-alpha_N PF04086.13 KND98766.1 - 8e-06 26.0 1.6 1.1e-05 25.5 1.6 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 KND98766.1 - 8.4e-05 22.7 0.0 0.00029 21.0 0.0 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 KND98766.1 - 0.00019 21.5 0.2 0.32 11.0 0.0 2.5 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 KND98766.1 - 0.00036 20.3 0.2 0.0016 18.2 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_31 PF13614.6 KND98766.1 - 0.0018 18.2 0.5 0.027 14.4 0.3 2.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KND98766.1 - 0.0036 17.1 0.0 0.0065 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KND98766.1 - 0.0074 15.5 0.0 0.59 9.3 0.0 2.5 1 1 1 2 2 2 1 Anion-transporting ATPase Zeta_toxin PF06414.12 KND98766.1 - 0.0084 15.4 0.0 0.32 10.2 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 KND98766.1 - 0.013 15.7 0.0 0.049 13.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KND98766.1 - 0.016 14.8 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KND98766.1 - 0.06 13.8 0.1 0.65 10.4 0.1 2.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KND98766.1 - 0.082 13.3 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Arginase PF00491.21 KND98768.1 - 1.1e-34 120.2 0.0 1.3e-34 120.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family WBP-1 PF11669.8 KND98770.1 - 0.042 14.5 0.9 0.049 14.3 0.9 1.1 1 0 0 1 1 1 0 WW domain-binding protein 1 A_deaminase PF00962.22 KND98772.1 - 8.8e-118 393.4 0.0 1.3e-117 392.9 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Phos_pyr_kin PF08543.12 KND98773.1 - 2e-65 220.6 0.2 3e-65 220.0 0.2 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KND98773.1 - 1.4e-31 109.9 0.1 2.1e-31 109.4 0.1 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family HK PF02110.15 KND98773.1 - 0.0029 17.0 0.2 1.3 8.4 0.1 2.2 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family DUF572 PF04502.13 KND98774.1 - 0.099 12.2 22.2 0.12 11.9 22.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) EF-hand_4 PF12763.7 KND98777.1 - 3.2e-22 78.4 0.0 1.1e-12 47.8 0.0 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.11 KND98777.1 - 4.4e-14 52.6 181.2 1.6e-06 28.4 53.8 11.9 7 3 5 12 12 12 5 Domain of unknown function (DUF1720) WH2 PF02205.20 KND98777.1 - 3.8e-05 23.4 0.1 0.00011 21.9 0.1 1.9 1 0 0 1 1 1 1 WH2 motif EF-hand_1 PF00036.32 KND98777.1 - 0.00017 20.9 0.0 0.13 11.9 0.0 3.2 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 KND98777.1 - 0.017 15.6 0.0 1.1 9.8 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain pair CBM9_1 PF06452.11 KND98777.1 - 0.025 14.5 0.8 0.065 13.1 0.8 1.6 1 0 0 1 1 1 0 Carbohydrate family 9 binding domain-like EF-hand_6 PF13405.6 KND98777.1 - 0.034 14.1 0.1 2.9 8.0 0.0 3.5 4 0 0 4 4 4 0 EF-hand domain E3_binding PF02817.17 KND98777.1 - 0.1 13.0 1.1 0.48 10.8 0.2 2.5 2 0 0 2 2 2 0 e3 binding domain Herpes_BBRF1 PF04793.12 KND98777.1 - 0.56 9.2 1.5 0.91 8.5 1.5 1.2 1 0 0 1 1 1 0 BRRF1-like protein AAA_2 PF07724.14 KND98778.1 - 1e-50 172.2 0.0 1e-50 172.2 0.0 3.0 4 0 0 4 4 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KND98778.1 - 2.4e-34 117.4 0.4 2.4e-34 117.4 0.4 2.7 1 1 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KND98778.1 - 2e-26 91.9 0.6 1e-25 89.6 0.1 2.6 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KND98778.1 - 4.5e-20 72.4 0.3 3.9e-10 40.3 0.1 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KND98778.1 - 2.1e-16 60.2 2.4 7.4e-11 42.2 0.0 3.5 3 2 1 4 4 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KND98778.1 - 2.9e-11 44.0 5.9 0.00011 22.6 0.1 4.6 3 2 0 3 3 2 2 AAA ATPase domain AAA_7 PF12775.7 KND98778.1 - 7.3e-09 35.4 0.9 0.0029 17.1 0.0 3.3 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_22 PF13401.6 KND98778.1 - 3.8e-08 33.7 2.5 0.011 16.0 0.1 4.2 2 2 2 4 4 4 2 AAA domain Sigma54_activat PF00158.26 KND98778.1 - 4.7e-08 32.9 0.1 2.8e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 KND98778.1 - 1.4e-06 28.4 4.9 0.029 14.4 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_28 PF13521.6 KND98778.1 - 1.7e-05 25.1 1.1 0.59 10.4 0.0 3.7 3 1 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 KND98778.1 - 4.3e-05 23.8 0.4 0.38 11.2 0.0 3.3 3 1 0 3 3 3 2 RNA helicase IstB_IS21 PF01695.17 KND98778.1 - 5.6e-05 23.0 0.0 0.25 11.1 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase_2 PF01637.18 KND98778.1 - 5.7e-05 23.1 13.3 1 9.2 0.2 4.8 3 2 2 5 5 5 3 ATPase domain predominantly from Archaea NACHT PF05729.12 KND98778.1 - 6.3e-05 22.9 0.2 0.24 11.3 0.0 3.0 3 0 0 3 3 3 2 NACHT domain AAA_30 PF13604.6 KND98778.1 - 0.00014 21.6 2.3 0.09 12.5 0.0 3.5 4 1 0 4 4 3 1 AAA domain PhoH PF02562.16 KND98778.1 - 0.00023 20.7 0.1 0.17 11.3 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein TsaE PF02367.17 KND98778.1 - 0.00029 20.8 0.0 1.4 8.9 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KND98778.1 - 0.00035 19.8 2.4 0.12 11.5 0.5 3.7 2 2 0 2 2 2 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 KND98778.1 - 0.00067 19.0 0.0 0.055 12.7 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.21 KND98778.1 - 0.001 18.5 0.1 1.8 7.9 0.0 3.2 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI Roc PF08477.13 KND98778.1 - 0.0011 19.1 0.1 1.1 9.5 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 KND98778.1 - 0.0018 17.9 0.1 0.42 10.2 0.0 3.1 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.9 KND98778.1 - 0.002 17.1 0.1 0.58 9.0 0.1 2.5 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.6 KND98778.1 - 0.0021 18.6 4.6 0.43 11.1 0.0 3.6 5 0 0 5 5 2 1 AAA domain DUF87 PF01935.17 KND98778.1 - 0.0022 18.1 5.3 1.3 9.0 0.0 3.9 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_6 PF12774.7 KND98778.1 - 0.0031 16.5 0.0 0.083 11.8 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_24 PF13479.6 KND98778.1 - 0.0033 17.2 0.1 0.67 9.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 KND98778.1 - 0.0037 17.0 0.1 0.5 10.1 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 KND98778.1 - 0.004 17.5 2.6 1.1 9.6 0.1 3.7 3 1 1 4 4 3 1 AAA domain Orbi_NS1 PF01718.16 KND98778.1 - 0.0059 15.1 0.0 0.0092 14.5 0.0 1.2 1 0 0 1 1 1 1 Orbivirus non-structural protein NS1, or hydrophobic tubular protein ResIII PF04851.15 KND98778.1 - 0.0081 16.2 7.0 1.3 9.0 0.0 3.7 4 1 0 5 5 3 2 Type III restriction enzyme, res subunit Torsin PF06309.11 KND98778.1 - 0.0081 16.3 0.0 0.072 13.2 0.0 2.3 2 0 0 2 2 2 1 Torsin AAA_33 PF13671.6 KND98778.1 - 0.011 15.9 0.0 2.3 8.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF853 PF05872.12 KND98778.1 - 0.013 14.1 5.7 0.027 13.1 0.1 3.0 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF853) ABC_tran PF00005.27 KND98778.1 - 0.016 15.7 6.2 0.86 10.1 0.0 3.8 3 1 0 3 3 3 0 ABC transporter T2SSE PF00437.20 KND98778.1 - 0.083 11.9 2.8 0.88 8.6 1.0 2.8 2 1 0 2 2 2 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KND98778.1 - 0.1 12.7 0.6 4.1 7.5 0.2 3.3 2 2 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 KND98778.1 - 0.12 12.1 0.1 7.5 6.4 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KND98778.1 - 0.12 11.9 0.0 18 4.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain dNK PF01712.19 KND98778.1 - 0.25 11.2 5.6 2.4 8.0 1.2 3.4 3 0 0 3 3 3 0 Deoxynucleoside kinase OEP PF02321.18 KND98778.1 - 0.27 11.0 5.4 0.47 10.2 5.4 1.3 1 0 0 1 1 1 0 Outer membrane efflux protein Cob_adeno_trans PF01923.18 KND98778.1 - 0.39 10.8 2.5 1.1 9.4 2.5 1.8 1 0 0 1 1 1 0 Cobalamin adenosyltransferase V_ATPase_I PF01496.19 KND98778.1 - 1.8 6.4 6.5 2.6 5.8 6.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.6 KND98778.1 - 2.3 8.7 25.2 40 4.6 0.0 3.7 2 1 0 2 2 2 0 AAA domain Seryl_tRNA_N PF02403.22 KND98778.1 - 2.4 8.4 16.1 1.5 9.1 11.3 3.2 2 1 1 3 3 2 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 KND98778.1 - 2.6 7.3 7.3 4.4 6.6 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UvrD-helicase PF00580.21 KND98778.1 - 3.3 7.1 12.4 1.5 8.3 0.1 2.8 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF4094 PF13334.6 KND98778.1 - 6.4 7.3 6.9 2.3 8.7 0.3 3.2 2 1 1 3 3 2 0 Domain of unknown function (DUF4094) Sec20 PF03908.13 KND98779.1 - 0.28 11.1 1.9 0.6 10.1 0.0 2.5 2 1 1 3 3 3 0 Sec20 RR_TM4-6 PF06459.12 KND98779.1 - 3.6 7.4 22.4 2 8.1 3.9 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RloB PF13707.6 KND98781.1 - 0.074 13.2 0.6 0.1 12.8 0.1 1.6 2 0 0 2 2 2 0 RloB-like protein PalH PF08733.10 KND98782.1 - 4.8e-57 193.4 19.8 6.6e-57 193.0 19.8 1.2 1 0 0 1 1 1 1 PalH/RIM21 HXXEE PF13787.6 KND98782.1 - 1.1 10.1 15.1 14 6.5 11.0 3.1 2 1 0 2 2 2 0 Protein of unknown function with HXXEE motif UNC45-central PF11701.8 KND98785.1 - 6e-16 58.8 5.2 2.3e-15 56.9 0.1 4.0 3 1 1 4 4 4 1 Myosin-binding striated muscle assembly central Arm PF00514.23 KND98785.1 - 0.0099 15.9 9.6 0.11 12.6 0.0 5.5 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KND98785.1 - 0.61 10.5 4.4 69 4.1 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat Sec23_trunk PF04811.15 KND98786.1 - 2.7e-45 154.8 0.0 5.5e-45 153.8 0.0 1.5 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KND98786.1 - 6.7e-18 64.4 0.5 1.4e-17 63.4 0.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KND98786.1 - 3.6e-15 56.5 0.0 7.6e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KND98786.1 - 5.2e-10 39.2 8.8 1e-09 38.3 8.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger TFIIA PF03153.13 KND98786.1 - 1.4 8.9 10.5 2 8.3 10.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Serglycin PF04360.12 KND98787.1 - 0.074 13.0 2.6 0.096 12.6 2.6 1.2 1 0 0 1 1 1 0 Serglycin AF-4 PF05110.13 KND98787.1 - 0.87 7.6 4.1 1 7.4 4.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Mgr1 PF08602.10 KND98790.1 - 5.3e-14 51.8 2.5 3e-05 23.1 0.0 4.0 1 1 2 3 3 3 3 Mgr1-like, i-AAA protease complex subunit PAXIP1_C PF15364.6 KND98790.1 - 0.19 12.0 1.3 2.5 8.4 0.1 2.2 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein HEPN_RiboL-PSP PF18735.1 KND98794.1 - 0.053 13.4 2.0 2.1 8.2 0.1 2.4 2 0 0 2 2 2 0 RiboL-PSP-HEPN bZIP_1 PF00170.21 KND98795.1 - 4.5e-08 33.1 17.1 1.1e-06 28.6 17.1 2.1 1 1 0 1 1 1 1 bZIP transcription factor DUF737 PF05300.11 KND98795.1 - 0.00051 20.5 5.0 0.00066 20.1 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF737) MPS2 PF17060.5 KND98795.1 - 0.0086 15.4 1.6 0.011 15.1 1.6 1.1 1 0 0 1 1 1 1 Monopolar spindle protein 2 TolA_bind_tri PF16331.5 KND98795.1 - 0.012 15.6 4.2 0.017 15.2 3.6 1.6 1 1 0 1 1 1 0 TolA binding protein trimerisation Cep57_CLD_2 PF14197.6 KND98795.1 - 0.014 15.4 4.7 0.028 14.5 4.7 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 CCDC92 PF14916.6 KND98795.1 - 0.059 13.1 1.1 0.13 12.0 1.1 1.7 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Hemagglutinin PF00509.18 KND98795.1 - 0.092 11.1 0.8 0.12 10.8 0.8 1.1 1 0 0 1 1 1 0 Haemagglutinin bZIP_2 PF07716.15 KND98795.1 - 0.28 11.3 17.3 0.31 11.1 2.0 2.2 1 1 1 2 2 2 0 Basic region leucine zipper DivIC PF04977.15 KND98795.1 - 0.43 10.4 5.0 0.12 12.2 1.5 1.8 1 1 1 2 2 2 0 Septum formation initiator Ndc1_Nup PF09531.10 KND98795.1 - 3.7 6.1 8.4 4.3 5.9 8.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AvrPto PF11592.8 KND98796.1 - 0.093 12.8 0.0 0.094 12.8 0.0 1.0 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto PBP PF01161.20 KND98801.1 - 0.016 15.5 0.1 0.037 14.4 0.1 1.5 1 0 0 1 1 1 0 Phosphatidylethanolamine-binding protein Qua1 PF16274.5 KND98801.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Qua1 domain MIF4G PF02854.19 KND98803.1 - 2.5e-14 53.5 22.0 1.1e-08 35.0 0.0 4.7 3 2 1 4 4 4 2 MIF4G domain Upf2 PF04050.14 KND98803.1 - 6.4e-10 39.9 0.5 2.5e-09 38.0 0.5 2.1 1 0 0 1 1 1 1 Up-frameshift suppressor 2 CDC45 PF02724.14 KND98803.1 - 1.5 7.0 10.4 2.6 6.2 10.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid_p PF12226.8 KND98803.1 - 2.9 7.0 12.0 4.8 6.2 12.0 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein SpoIIE PF07228.12 KND98804.1 - 4e-24 85.6 0.0 5.9e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KND98804.1 - 1.7e-07 31.2 2.0 0.0004 20.1 0.0 2.5 2 1 0 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.6 KND98804.1 - 1e-05 25.3 0.0 2.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C ATP-synt_E PF05680.12 KND98805.1 - 2.5e-22 79.0 0.3 2.8e-22 78.9 0.3 1.0 1 0 0 1 1 1 1 ATP synthase E chain FYVE PF01363.21 KND98806.1 - 7.4e-19 67.7 15.1 3.4e-15 55.9 0.8 2.9 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 KND98806.1 - 2e-11 43.4 0.4 5.6e-11 42.0 0.4 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 KND98806.1 - 0.00017 21.7 3.8 0.00017 21.7 3.8 3.1 3 1 1 4 4 4 1 AN1-like Zinc finger zf-Di19 PF05605.12 KND98806.1 - 0.00074 19.8 3.1 0.0032 17.7 0.3 2.7 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_12 PF18658.1 KND98806.1 - 0.047 13.3 1.8 0.1 12.2 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KND98806.1 - 1.2 10.2 0.0 1.2 10.2 0.0 5.0 6 1 1 7 7 7 0 C2H2-type zinc finger Sugar_tr PF00083.24 KND98808.1 - 1.4e-111 373.6 22.3 1.9e-111 373.2 22.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND98808.1 - 2e-19 69.8 22.0 2e-19 69.8 22.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.24 KND98809.1 - 0.0023 17.6 0.0 0.0024 17.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase CDC45 PF02724.14 KND98810.1 - 4.9e-195 649.5 0.5 6.1e-195 649.2 0.5 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF4380 PF14315.6 KND98810.1 - 0.17 10.8 0.0 0.46 9.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4380) DUF2415 PF10313.9 KND98811.1 - 3.1e-17 62.2 1.0 6.8e-17 61.1 1.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 KND98811.1 - 0.061 13.6 0.0 1.5 9.2 0.0 2.9 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Cation_efflux PF01545.21 KND98814.1 - 3.1e-53 180.5 0.6 3.8e-53 180.2 0.6 1.1 1 0 0 1 1 1 1 Cation efflux family Opi1 PF08618.10 KND98817.1 - 2e-19 70.2 17.2 2.9e-08 33.4 0.1 5.0 2 1 1 5 5 5 4 Transcription factor Opi1 DUF1993 PF09351.10 KND98817.1 - 0.076 13.2 2.6 0.11 12.6 0.5 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF1993) WW PF00397.26 KND98818.1 - 1.1e-09 38.2 1.9 1.9e-09 37.4 1.9 1.4 1 0 0 1 1 1 1 WW domain ETC_C1_NDUFA5 PF04716.14 KND98820.1 - 1.2e-28 98.6 0.2 2.1e-28 97.9 0.2 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region Ras PF00071.22 KND98821.1 - 1.5e-63 213.3 0.1 1.7e-63 213.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND98821.1 - 7.1e-37 126.3 0.1 1.4e-36 125.4 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND98821.1 - 1.3e-15 57.3 0.0 1.6e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KND98821.1 - 7.5e-07 28.7 0.0 9.2e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KND98821.1 - 1.7e-06 27.7 0.0 7.4e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KND98821.1 - 3e-05 24.0 0.4 0.19 11.6 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KND98821.1 - 6.1e-05 23.1 0.1 0.00014 21.9 0.1 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 KND98821.1 - 0.00013 21.5 0.0 0.00019 20.9 0.0 1.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KND98821.1 - 0.00072 19.1 0.0 0.0022 17.5 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_7 PF12775.7 KND98821.1 - 0.021 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 KND98821.1 - 0.021 14.1 0.1 0.05 12.9 0.1 1.6 1 0 0 1 1 1 0 Septin CENP-M PF11111.8 KND98821.1 - 0.023 13.9 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) AAA_22 PF13401.6 KND98821.1 - 0.031 14.5 0.1 0.12 12.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KND98821.1 - 0.038 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KND98821.1 - 0.042 13.6 0.3 0.14 11.8 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KND98821.1 - 0.076 13.4 0.1 0.13 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 KND98821.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein tRNA_synthFbeta PF17759.1 KND98822.1 - 2.1e-39 135.2 0.0 3.8e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KND98822.1 - 4.5e-28 97.3 0.5 6.1e-27 93.7 0.1 2.6 2 1 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KND98822.1 - 7.7e-27 94.1 0.0 1.4e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KND98822.1 - 1.9e-19 69.7 0.0 3.1e-16 59.4 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain VPS13 PF16908.5 KND98822.1 - 0.043 13.6 0.0 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 Vacuolar sorting-associated protein 13, N-terminal DUF726 PF05277.12 KND98823.1 - 7.1e-125 416.5 1.0 1.1e-124 415.9 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Methyltransf_34 PF11312.8 KND98824.1 - 2e-86 290.0 0.1 3.3e-86 289.3 0.1 1.3 1 1 0 1 1 1 1 Putative SAM-dependent methyltransferase SIR2 PF02146.17 KND98825.1 - 4.6e-56 189.5 0.0 7.3e-56 188.9 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Tim54 PF11711.8 KND98825.1 - 1.1 7.9 6.1 1.8 7.2 6.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Paired_CXXCH_1 PF09699.10 KND98825.1 - 1.2 9.0 4.4 2.8 7.8 4.4 1.7 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) NFACT-C PF11923.8 KND98826.1 - 5e-30 103.5 0.1 5e-30 103.5 0.1 3.6 3 0 0 3 3 3 1 NFACT protein C-terminal domain NFACT-R_1 PF05670.13 KND98826.1 - 1.6e-22 80.2 0.1 9.4e-22 77.7 0.0 2.5 3 0 0 3 3 3 1 NFACT protein RNA binding domain ADH_N PF08240.12 KND98827.1 - 1.6e-26 92.3 0.1 2.8e-26 91.5 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KND98827.1 - 3e-21 75.8 0.0 4.8e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KND98827.1 - 1.2e-13 52.3 0.0 1.9e-13 51.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KND98827.1 - 6.5e-05 22.3 0.0 9.9e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KND98827.1 - 0.11 12.4 0.0 0.65 9.9 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KND98827.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GST_C PF00043.25 KND98828.1 - 8.5e-23 80.4 0.0 1.5e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KND98828.1 - 1.4e-17 63.8 0.0 3.1e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KND98828.1 - 1.1e-10 41.8 0.0 2.2e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KND98828.1 - 1.4e-08 34.9 0.0 3e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KND98828.1 - 3.6e-05 23.9 0.0 8e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KND98828.1 - 0.036 14.1 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF3824 PF12868.7 KND98829.1 - 0.59 10.8 3.8 0.62 10.7 3.8 1.0 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) GATase PF00117.28 KND98830.1 - 4.3e-07 29.9 0.0 1.1e-06 28.6 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Cyt-b5 PF00173.28 KND98834.1 - 3e-11 43.3 0.0 3.8e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Flavi_M PF01004.19 KND98834.1 - 0.18 11.6 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M RRM_1 PF00076.22 KND98835.1 - 3.4e-17 62.0 0.0 6.3e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 KND98835.1 - 6.7e-14 52.3 5.5 6.7e-14 52.3 5.5 1.8 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_7 PF16367.5 KND98835.1 - 0.0022 18.1 0.0 0.005 16.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif DUF2541 PF10807.8 KND98835.1 - 0.14 12.2 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2541) PPR_3 PF13812.6 KND98836.1 - 0.0063 16.6 0.1 0.026 14.6 0.1 2.2 2 0 0 2 2 2 1 Pentatricopeptide repeat domain Glyco_hydro_8 PF01270.17 KND98836.1 - 0.078 11.8 0.1 0.13 11.1 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 8 Kri1_C PF12936.7 KND98839.1 - 1.3e-29 102.2 4.1 1.3e-29 102.2 4.1 4.6 3 2 1 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.12 KND98839.1 - 3.4e-19 69.3 13.6 3.4e-19 69.3 13.6 5.7 3 1 0 4 4 4 1 KRI1-like family Effector_1 PF04518.12 KND98839.1 - 1.2 8.1 7.8 0.044 12.9 0.8 2.0 2 0 0 2 2 2 0 Effector from type III secretion system CorA PF01544.18 KND98840.1 - 2.1e-39 135.6 0.7 1.6e-25 90.0 0.0 2.5 3 0 0 3 3 3 2 CorA-like Mg2+ transporter protein Coprogen_oxidas PF01218.18 KND98843.1 - 1.8e-136 453.7 0.1 2e-136 453.5 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase XLF PF09302.11 KND98844.1 - 2.4e-12 47.4 0.0 3.7e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component AAA_33 PF13671.6 KND98845.1 - 5.8e-06 26.5 0.0 0.00077 19.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 KND98845.1 - 3e-05 23.9 0.0 4.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family MeaB PF03308.16 KND98845.1 - 5.7e-05 22.2 0.0 9.6e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KND98845.1 - 7.8e-05 23.1 0.1 0.00019 21.8 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KND98845.1 - 0.00062 20.3 0.0 0.0018 18.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KND98845.1 - 0.00062 19.5 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KND98845.1 - 0.0011 18.4 0.0 0.0032 16.9 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 KND98845.1 - 0.0017 17.7 0.1 0.0068 15.7 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin NTPase_1 PF03266.15 KND98845.1 - 0.0023 17.9 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 NTPase AAA_17 PF13207.6 KND98845.1 - 0.0066 16.9 0.1 0.072 13.5 0.1 2.2 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 KND98845.1 - 0.008 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KND98845.1 - 0.0086 16.4 0.1 0.021 15.1 0.0 1.7 1 1 1 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KND98845.1 - 0.0088 15.8 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 KND98845.1 - 0.011 15.7 0.0 0.039 13.9 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 KND98845.1 - 0.023 14.8 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.14 KND98845.1 - 0.027 14.4 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 KND98845.1 - 0.036 13.3 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 KND98845.1 - 0.048 13.6 0.1 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 KND98845.1 - 0.065 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 KND98845.1 - 0.084 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein TsaE PF02367.17 KND98845.1 - 0.088 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KND98845.1 - 0.098 12.2 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KND98845.1 - 0.1 13.1 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter SRP54 PF00448.22 KND98845.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PIN_4 PF13638.6 KND98846.1 - 1.6e-32 112.6 1.6 5.4e-32 110.8 0.4 2.4 3 0 0 3 3 3 1 PIN domain PIN_9 PF18477.1 KND98846.1 - 7.9e-05 22.9 0.6 0.00069 19.9 0.6 2.3 1 1 0 1 1 1 1 PIN like domain PIN_12 PF16289.5 KND98846.1 - 0.0033 17.9 0.8 0.0081 16.7 0.1 2.0 2 1 0 2 2 2 1 PIN domain DUF155 PF02582.14 KND98847.1 - 1.7e-50 171.5 0.8 3.4e-50 170.6 0.1 1.8 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 tRNA-synt_1c PF00749.21 KND98848.1 - 5.3e-117 390.2 0.0 7.2e-117 389.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KND98848.1 - 2.1e-40 138.5 3.6 5e-40 137.2 3.6 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GluRS_N PF18466.1 KND98848.1 - 3.1e-11 43.5 3.8 6.3e-11 42.5 2.0 2.6 2 0 0 2 2 2 1 Glutamate--tRNA ligase N-terminal domain GST_C PF00043.25 KND98848.1 - 2e-05 24.7 0.1 8.4e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KND98848.1 - 2.8e-05 24.0 0.0 8.1e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KND98848.1 - 0.0058 16.8 0.0 0.021 15.0 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF720 PF05302.11 KND98848.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF720) NADHdh PF00146.21 KND98849.1 - 1.2e-25 90.5 2.0 1.3e-25 90.3 2.0 1.0 1 0 0 1 1 1 1 NADH dehydrogenase COX1 PF00115.20 KND98851.1 - 1.8e-15 56.7 4.2 2e-15 56.6 4.2 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I CTD_bind PF04818.13 KND98852.1 - 1.7e-19 70.4 0.9 5.8e-19 68.7 0.1 2.4 3 0 0 3 3 3 1 RNA polymerase II-binding domain. CDC27 PF09507.10 KND98852.1 - 0.12 11.7 14.7 0.19 11.1 14.7 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4164 PF13747.6 KND98852.1 - 0.23 11.7 6.5 0.57 10.5 6.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) ANAPC_CDC26 PF10471.9 KND98852.1 - 0.41 11.5 0.2 0.41 11.5 0.2 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Zn_clus PF00172.18 KND98853.1 - 2e-05 24.6 16.4 3.5e-05 23.8 16.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UvrD-helicase PF00580.21 KND98854.1 - 1.5e-33 116.7 0.0 1.2e-29 103.9 0.0 3.6 2 2 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KND98854.1 - 7.5e-22 78.2 0.0 1.4e-20 73.9 0.0 2.6 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KND98854.1 - 1.3e-20 74.2 0.3 5.6e-20 72.2 0.3 2.1 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 KND98854.1 - 6.1e-11 42.0 0.0 2.3e-10 40.1 0.0 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 KND98854.1 - 1.6e-05 24.9 0.0 0.0001 22.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KND98854.1 - 0.00021 21.1 0.0 0.00077 19.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KND98854.1 - 0.00051 19.9 0.0 0.027 14.2 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 KND98854.1 - 0.0057 16.3 0.0 3.3 7.3 0.0 3.1 3 1 0 3 3 3 2 AAA domain MukB PF04310.12 KND98854.1 - 0.0069 16.2 0.0 0.51 10.1 0.0 2.4 1 1 1 2 2 2 1 MukB N-terminal PAZ PF02170.22 KND98854.1 - 0.026 14.3 0.1 0.057 13.2 0.1 1.5 1 0 0 1 1 1 0 PAZ domain ResIII PF04851.15 KND98854.1 - 0.086 12.8 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Snapin_Pallidin PF14712.6 KND98854.1 - 0.14 12.6 1.1 0.62 10.5 0.1 2.6 3 0 0 3 3 3 0 Snapin/Pallidin Helicase_RecD PF05127.14 KND98854.1 - 0.21 11.4 0.5 0.78 9.6 0.0 2.1 3 0 0 3 3 3 0 Helicase DUF2075 PF09848.9 KND98854.1 - 0.32 10.2 0.8 2.2 7.4 0.0 2.6 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2075) Synapsin_N PF10581.9 KND98854.1 - 0.85 9.6 5.8 0.22 11.5 1.5 2.1 2 0 0 2 2 2 0 Synapsin N-terminal Vps52 PF04129.12 KND98855.1 - 4.5e-73 246.7 4.8 4e-49 167.7 0.7 2.0 2 0 0 2 2 2 2 Vps52 / Sac2 family Rep_fac_C PF08542.11 KND98856.1 - 2.6e-21 75.8 0.0 7.4e-21 74.4 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 KND98856.1 - 4.1e-11 43.4 0.0 7.1e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KND98856.1 - 1.3e-10 41.2 0.1 1.9e-08 34.2 0.1 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 KND98856.1 - 9e-07 29.0 0.0 1.5e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KND98856.1 - 1e-06 28.6 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KND98856.1 - 8.7e-06 26.2 0.0 0.0018 18.7 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KND98856.1 - 3e-05 23.8 0.0 8.5e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KND98856.1 - 3.5e-05 24.1 0.1 0.1 12.9 0.0 2.4 1 1 1 2 2 2 2 AAA domain Rad17 PF03215.15 KND98856.1 - 0.00031 20.7 0.0 0.0006 19.8 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain Viral_helicase1 PF01443.18 KND98856.1 - 0.0015 18.4 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 KND98856.1 - 0.0017 17.8 0.0 0.02 14.3 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_assoc_2 PF16193.5 KND98856.1 - 0.017 15.5 0.0 0.047 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain TniB PF05621.11 KND98856.1 - 0.02 14.3 0.1 6.1 6.2 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein AAA_19 PF13245.6 KND98856.1 - 0.027 14.8 0.0 0.15 12.4 0.0 2.3 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 KND98856.1 - 0.06 12.3 0.0 0.81 8.6 0.0 2.3 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FtsK_SpoIIIE PF01580.18 KND98856.1 - 0.097 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_5 PF07728.14 KND98856.1 - 0.13 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KND98856.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KND98856.1 - 0.16 11.9 0.1 0.51 10.2 0.1 1.9 1 1 1 2 2 2 0 NTPase AAA_7 PF12775.7 KND98856.1 - 0.17 11.3 0.3 0.33 10.5 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region RNase_P_pop3 PF08228.11 KND98857.1 - 3e-14 53.4 0.0 5.1e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 RNase P subunit Pop3 RNA_pol_Rpb1_5 PF04998.17 KND98858.1 - 8.9e-110 366.3 0.1 1.3e-109 365.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 KND98858.1 - 1.2e-100 336.9 0.0 2.3e-100 335.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 KND98858.1 - 6.1e-77 257.5 0.0 2.8e-76 255.3 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KND98858.1 - 2.3e-65 220.0 0.1 5.3e-65 218.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 KND98858.1 - 3e-50 169.7 2.7 3e-50 169.7 2.7 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 KND98858.1 - 4.3e-50 169.7 0.0 9e-50 168.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KND98858.1 - 1.3e-37 128.1 0.1 3.2e-37 126.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KND98858.1 - 5e-25 86.5 353.2 0.0043 17.3 9.9 18.1 7 1 7 21 21 21 19 RNA polymerase Rpb1 C-terminal repeat Alpha-amylase PF00128.24 KND98859.1 - 2.7e-123 411.8 1.4 2.7e-123 411.8 1.4 1.6 2 0 0 2 2 2 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KND98859.1 - 0.00019 20.7 0.2 0.0023 17.1 0.0 2.3 2 0 0 2 2 2 1 Glycogen debranching enzyme, glucanotransferase domain Malt_amylase_C PF16657.5 KND98859.1 - 0.0024 17.9 0.1 0.005 16.9 0.1 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Na_Ca_ex PF01699.24 KND98860.1 - 2.5e-23 82.7 47.6 1.5e-17 64.0 14.0 4.1 4 1 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 KND98860.1 - 2.8e-14 53.5 5.3 2.8e-14 53.5 5.3 4.7 6 0 0 6 6 6 1 Inner membrane component domain DUF3295 PF11702.8 KND98860.1 - 0.061 12.7 8.8 0.17 11.2 8.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DER1 PF04511.15 KND98861.1 - 5.6e-25 88.4 16.0 1.5e-21 77.2 11.3 2.1 2 0 0 2 2 2 2 Der1-like family EIIC-GAT PF03611.14 KND98861.1 - 0.16 11.0 3.7 0.22 10.6 3.7 1.2 1 0 0 1 1 1 0 PTS system sugar-specific permease component LSM PF01423.22 KND98862.1 - 9.9e-12 44.4 0.0 1.3e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain Mitoc_mL59 PF18126.1 KND98863.1 - 2.8e-32 111.7 1.1 4.3e-32 111.1 1.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 AMP_N PF05195.16 KND98863.1 - 0.023 14.4 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain ATP-synt_DE_N PF02823.16 KND98864.1 - 6.6e-17 61.2 0.0 1.1e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain HisKA_2 PF07568.12 KND98864.1 - 0.064 13.3 0.2 2.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Histidine kinase Med2 PF11214.8 KND98865.1 - 8.4e-34 115.7 0.5 8.4e-34 115.7 0.5 4.0 1 1 1 2 2 1 1 Mediator complex subunit 2 Caldesmon PF02029.15 KND98865.1 - 0.00019 20.4 30.7 0.00023 20.1 30.7 1.1 1 0 0 1 1 1 1 Caldesmon Dsh_C PF12316.8 KND98865.1 - 0.007 16.8 1.7 0.011 16.2 1.7 1.2 1 0 0 1 1 1 1 Segment polarity protein dishevelled (Dsh) C terminal Presenilin PF01080.17 KND98865.1 - 0.05 12.4 16.9 0.059 12.1 16.9 1.1 1 0 0 1 1 1 0 Presenilin GAGA_bind PF06217.12 KND98865.1 - 0.078 13.3 12.7 0.1 12.9 12.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family MMR1 PF08505.10 KND98865.1 - 0.089 13.1 13.9 0.12 12.7 13.9 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein CDC45 PF02724.14 KND98865.1 - 0.096 11.0 27.0 0.12 10.7 27.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2151 PF10221.9 KND98865.1 - 0.19 10.3 12.6 0.22 10.1 12.6 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DUF765 PF05570.11 KND98865.1 - 0.2 11.9 0.2 0.34 11.1 0.2 1.3 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF765) ALMT PF11744.8 KND98865.1 - 0.33 9.7 12.7 0.4 9.5 12.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter NPR3 PF03666.13 KND98865.1 - 0.95 8.2 19.2 1.3 7.8 19.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Sec62 PF03839.16 KND98865.1 - 1.6 8.2 14.0 2.3 7.7 14.0 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Asp-B-Hydro_N PF05279.11 KND98865.1 - 2.3 8.2 33.6 3.5 7.6 33.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SOBP PF15279.6 KND98865.1 - 2.5 8.6 5.3 3.5 8.2 5.3 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Hid1 PF12722.7 KND98865.1 - 2.5 6.1 17.0 2.9 5.9 17.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF5401 PF17380.2 KND98865.1 - 2.6 6.0 40.1 3.1 5.8 40.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) LRIF1 PF15741.5 KND98865.1 - 8.7 4.7 16.0 11 4.4 16.0 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Rad21_Rec8_N PF04825.13 KND98867.1 - 4.6e-28 97.6 0.0 1e-27 96.5 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KND98867.1 - 2e-07 30.2 0.0 5.1e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein WD40 PF00400.32 KND98868.1 - 0.024 15.5 8.5 9.2 7.3 0.2 4.1 5 0 0 5 5 5 0 WD domain, G-beta repeat SLD5_C PF16922.5 KND98869.1 - 9.6e-11 41.7 1.2 2e-10 40.7 1.2 1.6 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KND98869.1 - 4.4e-06 27.1 2.3 1.2e-05 25.8 2.3 1.9 1 1 0 1 1 1 1 GINS complex protein WD40 PF00400.32 KND98870.1 - 8.3e-13 48.6 3.6 0.00021 22.0 0.1 5.7 5 0 0 5 5 5 2 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 KND98870.1 - 4.1e-07 29.5 9.7 9.9e-07 28.3 9.7 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 KND98870.1 - 4.2e-05 23.8 5.8 0.00019 21.7 5.8 2.3 1 0 0 1 1 1 1 Ring finger domain ANAPC4_WD40 PF12894.7 KND98870.1 - 0.0071 16.6 0.1 0.09 13.1 0.0 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain zf-C3HC4 PF00097.25 KND98870.1 - 0.13 12.2 7.2 0.61 10.0 7.2 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KND98870.1 - 0.21 11.9 12.2 0.57 10.5 12.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain MC1 PF05854.11 KND98870.1 - 0.22 11.8 2.3 0.5 10.7 0.9 2.1 2 0 0 2 2 2 0 Non-histone chromosomal protein MC1 zf-C3HC4_2 PF13923.6 KND98870.1 - 1.6 8.6 9.0 0.087 12.7 2.9 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Hydrolase_4 PF12146.8 KND98872.1 - 8.5e-19 67.8 0.0 7.1e-12 45.1 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KND98872.1 - 2.1e-11 43.9 0.1 7.8e-07 29.0 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KND98872.1 - 0.00085 19.2 0.2 0.28 11.0 0.1 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase AXE1 PF05448.12 KND98872.1 - 0.0013 17.5 0.1 1.4 7.5 0.0 2.5 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) DUF818 PF05677.12 KND98872.1 - 0.0025 16.9 0.1 0.0039 16.2 0.1 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.21 KND98872.1 - 0.0055 16.2 0.2 0.041 13.3 0.2 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 KND98872.1 - 0.019 14.6 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) BAAT_C PF08840.11 KND98872.1 - 0.029 14.3 0.1 13 5.7 0.0 2.8 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 KND98872.1 - 0.19 12.3 0.0 0.31 11.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family IF4E PF01652.18 KND98873.1 - 8.3e-55 184.9 0.5 1e-54 184.7 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E KRE1 PF17056.5 KND98874.1 - 4.3e-19 68.0 15.0 4.3e-19 68.0 15.0 1.4 2 0 0 2 2 2 1 Killer toxin-resistance protein 1 Aa_trans PF01490.18 KND98875.1 - 2.9e-79 266.7 33.3 4.6e-79 266.0 33.3 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein ApoO PF09769.9 KND98876.1 - 3e-17 62.8 0.7 1.6e-16 60.4 0.1 2.1 2 0 0 2 2 2 1 Apolipoprotein O ApbA_C PF08546.11 KND98877.1 - 5.8e-10 39.4 0.0 1.2e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DUF603 PF04645.12 KND98877.1 - 0.021 14.5 0.6 0.037 13.7 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF603 FapA PF03961.13 KND98877.1 - 0.36 9.4 15.5 0.033 12.8 9.9 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF3552 PF12072.8 KND98877.1 - 2 7.8 29.2 0.2 11.1 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Golgin_A5 PF09787.9 KND98877.1 - 8.5 5.7 30.2 0.073 12.5 18.2 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 HARP PF07443.13 KND98879.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 HepA-related protein (HARP) Thymidylate_kin PF02223.17 KND98880.1 - 1.1e-38 132.7 0.0 1.3e-38 132.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.6 KND98880.1 - 2e-05 25.1 0.0 3.9e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KND98880.1 - 0.0016 18.6 0.0 0.0025 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain dNK PF01712.19 KND98880.1 - 0.003 17.4 0.0 0.012 15.5 0.0 1.9 1 1 0 1 1 1 1 Deoxynucleoside kinase CPT PF07931.12 KND98880.1 - 0.058 13.2 0.0 0.19 11.5 0.0 1.8 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Clat_adaptor_s PF01217.20 KND98881.1 - 6.2e-50 168.8 4.9 7e-50 168.6 4.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TFIID_NTD2 PF04494.15 KND98881.1 - 0.037 14.3 2.2 0.05 13.8 2.2 1.3 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain Ku PF02735.16 KND98882.1 - 3.2e-24 85.8 0.1 6e-24 84.9 0.1 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.14 KND98882.1 - 6.4e-08 33.2 0.5 6.4e-08 33.2 0.5 3.1 3 0 0 3 3 3 1 Ku70/Ku80 C-terminal arm Ku_N PF03731.15 KND98882.1 - 0.0028 17.4 0.6 0.0028 17.4 0.6 2.0 2 1 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain KHA PF11834.8 KND98885.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel IMUP PF15761.5 KND98885.1 - 2.3 8.9 9.6 8.4 7.1 4.8 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein Zn_clus PF00172.18 KND98892.1 - 2.8e-08 33.7 15.3 4.2e-08 33.2 15.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain His_Phos_1 PF00300.22 KND98893.1 - 5.3e-05 23.0 0.0 0.00016 21.5 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HEAT PF02985.22 KND98894.1 - 1.3e-38 127.7 8.5 0.0027 17.8 0.0 12.7 13 0 0 13 13 13 8 HEAT repeat HEAT_2 PF13646.6 KND98894.1 - 1.6e-27 95.7 0.2 4.6e-09 36.5 0.0 8.1 4 3 5 9 9 9 7 HEAT repeats Vac14_Fab1_bd PF12755.7 KND98894.1 - 1.5e-10 41.5 1.8 0.0076 16.8 0.0 6.4 5 2 1 7 7 7 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KND98894.1 - 1.7e-07 31.4 11.0 7.9e-05 22.8 0.3 5.9 2 2 5 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KND98894.1 - 3.3e-06 26.0 5.6 0.0036 15.9 0.2 4.0 1 1 3 4 4 4 3 Adaptin N terminal region HEAT_EZ PF13513.6 KND98894.1 - 1.8e-05 25.1 6.7 3.4 8.3 0.0 7.3 8 0 0 8 8 8 1 HEAT-like repeat RTP1_C1 PF10363.9 KND98894.1 - 0.0015 18.7 3.2 1.3 9.2 0.1 4.9 5 0 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 TAF6_C PF07571.13 KND98894.1 - 0.0018 18.5 0.0 1.1 9.6 0.1 4.3 2 1 1 3 3 3 1 TAF6 C-terminal HEAT repeat domain API5 PF05918.11 KND98894.1 - 0.002 17.0 1.6 0.22 10.3 0.3 3.6 3 1 2 5 5 5 1 Apoptosis inhibitory protein 5 (API5) DUF3385 PF11865.8 KND98894.1 - 0.027 14.4 0.2 0.2 11.6 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) M11L PF11099.8 KND98894.1 - 0.032 14.5 5.9 4.6 7.5 1.0 3.7 2 2 2 4 4 4 0 Apoptosis regulator M11L like CLASP_N PF12348.8 KND98894.1 - 0.13 11.8 1.7 9.3 5.7 0.1 4.2 5 2 1 6 6 6 0 CLASP N terminal Cohesin_HEAT PF12765.7 KND98894.1 - 5.9 7.3 7.6 64 4.0 0.1 4.4 5 0 0 5 5 4 0 HEAT repeat associated with sister chromatid cohesion Fe-S_biosyn PF01521.20 KND98895.1 - 8.8e-13 48.4 0.2 1.4e-12 47.8 0.2 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis PMT PF02366.18 KND98896.1 - 3.8e-90 301.7 17.4 3.8e-90 301.7 17.4 1.9 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KND98896.1 - 3e-60 203.3 10.6 3e-60 203.3 10.6 2.6 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KND98896.1 - 5.6e-24 85.0 0.0 9.7e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KND98896.1 - 4.1e-06 27.1 9.6 4.1e-06 27.1 9.6 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Gp_dh_C PF02800.20 KND98900.1 - 2.4e-69 232.0 0.0 3.5e-69 231.4 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KND98900.1 - 2.2e-39 133.9 0.0 4.7e-39 132.8 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KND98900.1 - 0.022 14.9 0.4 0.067 13.3 0.2 2.1 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 KND98900.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SYCP2_ARLD PF18581.1 KND98901.1 - 0.041 13.9 0.0 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 Synaptonemal complex 2 armadillo-repeat-like domain SPX PF03105.19 KND98902.1 - 1.6e-06 28.3 0.0 1.6e-06 28.3 0.0 3.0 3 1 0 3 3 3 1 SPX domain DUF1265 PF06887.14 KND98902.1 - 0.31 11.0 2.7 4.5 7.3 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1265) NIR_SIR PF01077.22 KND98904.1 - 1.7e-51 173.9 0.0 3.5e-50 169.6 0.0 2.3 2 0 0 2 2 2 1 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KND98904.1 - 7e-31 105.9 0.0 3.9e-14 52.3 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KND98904.1 - 1e-27 97.1 0.1 2.4e-27 95.9 0.1 1.7 1 0 0 1 1 1 1 Flavodoxin VWA_2 PF13519.6 KND98906.1 - 1.7e-21 76.9 0.7 1.5e-20 73.8 0.0 2.3 2 1 1 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 KND98906.1 - 2.1e-07 31.4 0.6 3.2e-07 30.8 0.6 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 KND98906.1 - 0.00037 20.4 0.0 0.00049 20.0 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 KND98906.1 - 0.0053 16.6 0.3 0.016 15.1 0.3 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF4362 PF14275.6 KND98906.1 - 0.016 15.5 0.1 4.2 7.7 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4362) Prp18 PF02840.15 KND98906.1 - 0.044 13.8 0.2 0.044 13.8 0.2 1.5 2 0 0 2 2 2 0 Prp18 domain Phage_T4_Ndd PF06591.11 KND98907.1 - 0.011 15.5 0.0 0.04 13.7 0.0 2.0 2 0 0 2 2 2 0 T4-like phage nuclear disruption protein (Ndd) Swi3 PF07962.12 KND98908.1 - 1.6e-18 66.4 0.3 2.6e-18 65.8 0.3 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 TSA PF03249.13 KND98909.1 - 0.053 12.3 0.0 0.057 12.2 0.0 1.0 1 0 0 1 1 1 0 Type specific antigen Phage_P2_GpE PF06528.12 KND98909.1 - 0.058 12.9 0.2 0.088 12.4 0.2 1.3 1 0 0 1 1 1 0 Phage P2 GpE HECT_2 PF09814.9 KND98913.1 - 4e-58 197.1 2.7 8.9e-58 195.9 2.7 1.5 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DHHA2 PF02833.14 KND98914.1 - 2.8e-26 92.4 0.0 5.8e-26 91.4 0.0 1.5 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 KND98914.1 - 2.8e-09 37.1 0.0 5.8e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 DHH family TetR_C_24 PF17932.1 KND98914.1 - 0.017 15.4 0.0 0.45 10.8 0.0 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain PMT PF02366.18 KND98915.1 - 9e-79 264.5 22.6 9e-79 264.5 22.6 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KND98915.1 - 9.5e-60 201.6 6.5 9.5e-60 201.6 6.5 2.9 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KND98915.1 - 5.4e-11 42.7 0.1 9.1e-11 41.9 0.1 1.3 1 0 0 1 1 1 1 MIR domain Hamartin PF04388.12 KND98916.1 - 9.4e-05 21.3 0.1 9.4e-05 21.3 0.1 3.0 3 1 0 3 3 3 1 Hamartin protein SOGA PF11365.8 KND98916.1 - 0.078 14.1 19.1 0.097 13.8 4.0 3.6 2 2 1 3 3 3 0 Protein SOGA FlaC_arch PF05377.11 KND98916.1 - 0.19 12.1 14.1 1.6 9.1 0.7 4.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Filament PF00038.21 KND98916.1 - 0.33 10.5 25.0 0.34 10.5 20.2 3.1 2 1 0 2 2 2 0 Intermediate filament protein Phage_GP20 PF06810.11 KND98916.1 - 0.43 10.4 12.5 1.3 8.8 0.5 2.9 2 0 0 2 2 2 0 Phage minor structural protein GP20 DivIC PF04977.15 KND98916.1 - 2.1 8.2 6.4 1.1 9.1 1.2 2.9 2 0 0 2 2 2 0 Septum formation initiator MFS_1 PF07690.16 KND98918.1 - 4.9e-40 137.5 35.1 4.1e-39 134.5 27.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND98918.1 - 4.7e-11 42.2 8.3 4.7e-11 42.2 8.3 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KND98918.1 - 3.1e-07 29.2 2.2 4.7e-07 28.6 2.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KND98918.1 - 0.0012 18.3 1.3 0.0012 18.3 1.3 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF4574 PF15141.6 KND98918.1 - 0.018 14.9 0.2 0.1 12.5 0.0 2.2 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 PQ-loop PF04193.14 KND98920.1 - 3.7e-21 74.7 8.4 5.9e-17 61.2 2.5 2.5 2 0 0 2 2 2 2 PQ loop repeat ABC2_membrane_5 PF13346.6 KND98920.1 - 6.9 6.2 14.9 1.3 8.5 9.7 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein Rad4 PF03835.15 KND98921.1 - 7.2e-28 97.1 2.4 2.6e-27 95.3 2.4 1.9 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KND98921.1 - 6.2e-17 61.8 0.0 1.4e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KND98921.1 - 2e-16 59.5 0.0 4.3e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KND98921.1 - 1.1e-11 45.6 3.1 2.6e-11 44.3 0.5 3.1 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KND98921.1 - 0.0081 16.6 0.0 0.023 15.2 0.0 1.8 1 1 0 1 1 1 1 Transglutaminase-like superfamily Lyase_1 PF00206.20 KND98924.1 - 4.1e-117 391.0 0.0 5.5e-117 390.6 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KND98924.1 - 3.4e-25 88.2 0.0 7.6e-25 87.1 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus AATase PF07247.12 KND98925.1 - 9e-53 179.5 0.2 1.2e-52 179.2 0.2 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 KND98925.1 - 0.012 14.4 0.0 0.044 12.5 0.0 1.7 2 0 0 2 2 2 0 Condensation domain HK PF02110.15 KND98926.1 - 2.5e-70 236.7 0.0 3.9e-70 236.0 0.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KND98926.1 - 1.5e-59 200.3 0.1 6.9e-58 194.9 0.1 2.2 2 0 0 2 2 2 2 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 KND98926.1 - 3e-05 23.5 0.1 0.00011 21.7 0.0 1.9 2 1 1 3 3 3 1 Phosphomethylpyrimidine kinase WLM PF08325.10 KND98927.1 - 5.4e-51 173.4 0.1 1.6e-50 171.9 0.0 1.8 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.17 KND98927.1 - 0.024 14.7 0.2 0.024 14.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF45 INSIG PF07281.12 KND98928.1 - 1e-24 87.4 7.1 2.6e-24 86.1 7.1 1.7 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) DUF3792 PF12670.7 KND98928.1 - 4 7.6 10.3 0.52 10.5 5.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Autophagy_act_C PF03987.15 KND98930.1 - 0.013 16.1 2.6 0.013 16.1 2.6 2.1 2 1 0 2 2 2 0 Autophagocytosis associated protein, active-site domain Endosulfine PF04667.17 KND98931.1 - 4.1e-30 103.7 0.8 5.6e-30 103.3 0.8 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Pga1 PF10333.9 KND98932.1 - 4.4e-30 104.8 3.4 5.6e-30 104.5 3.4 1.1 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator DUF4840 PF16128.5 KND98932.1 - 0.0063 16.6 1.2 0.012 15.6 1.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4840) F-box-like PF12937.7 KND98933.1 - 0.023 14.6 0.7 0.27 11.2 0.1 2.6 2 0 0 2 2 2 0 F-box-like NVEALA PF14055.6 KND98934.1 - 0.017 15.1 1.2 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 NVEALA protein COX4_pro_2 PF07835.12 KND98934.1 - 4 7.6 7.8 14 5.9 0.9 2.1 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV CFEM PF05730.11 KND98936.1 - 5.4e-13 48.8 6.4 7.4e-13 48.4 6.4 1.2 1 0 0 1 1 1 1 CFEM domain CTK3 PF12243.8 KND98937.1 - 0.089 12.8 0.0 0.27 11.2 0.0 1.8 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Septin PF00735.18 KND98938.1 - 2.2e-89 299.5 0.1 3.9e-89 298.7 0.1 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KND98938.1 - 1.2e-05 25.3 0.0 2.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KND98938.1 - 0.0052 16.7 0.0 0.031 14.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase T2SSE PF00437.20 KND98938.1 - 0.0052 15.9 0.0 0.015 14.4 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 KND98938.1 - 0.015 15.6 0.0 0.1 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 KND98938.1 - 0.022 14.2 0.1 0.043 13.3 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_24 PF13479.6 KND98938.1 - 0.04 13.6 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KND98938.1 - 0.053 13.9 0.0 0.17 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.10 KND98938.1 - 0.06 12.8 0.7 0.1 12.0 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KND98938.1 - 0.061 13.8 0.0 0.41 11.1 0.0 2.4 3 0 0 3 3 3 0 ABC transporter RNA_helicase PF00910.22 KND98938.1 - 0.17 12.3 0.0 0.52 10.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.18 KND98938.1 - 0.18 11.1 4.5 0.24 10.7 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family PIN_4 PF13638.6 KND98939.1 - 9e-06 26.0 0.0 5.5e-05 23.5 0.0 2.2 1 1 0 1 1 1 1 PIN domain SNF2_N PF00176.23 KND98940.1 - 1.4e-72 244.3 1.9 4.6e-72 242.7 1.9 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KND98940.1 - 1.7e-21 76.6 4.4 1.7e-19 70.2 0.0 3.6 4 0 0 4 4 4 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 KND98940.1 - 4.4e-20 71.6 0.2 1.3e-19 70.0 0.2 1.8 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.6 KND98940.1 - 3.8e-13 49.9 5.2 3.8e-13 49.9 5.2 3.4 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 KND98940.1 - 1.4e-09 38.2 0.5 1.4e-09 38.2 0.5 3.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HSA PF07529.13 KND98940.1 - 5e-07 30.0 12.0 5e-07 30.0 12.0 3.4 3 0 0 3 3 3 1 HSA Vps36_ESCRT-II PF11605.8 KND98941.1 - 0.0026 17.9 0.1 0.0063 16.7 0.1 1.7 1 1 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 RrnaAD PF00398.20 KND98942.1 - 1.3e-27 96.5 0.0 1.6e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 KND98942.1 - 0.006 16.6 0.0 0.0096 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Suf PF05843.14 KND98944.1 - 3.1e-58 198.1 18.3 1.5e-57 195.9 3.1 4.4 3 2 0 3 3 3 2 Suppressor of forked protein (Suf) Tom37 PF10568.9 KND98945.1 - 2.3e-30 105.5 1.7 3.5e-30 104.9 1.7 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KND98945.1 - 0.011 16.5 0.0 0.024 15.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Tom37_C PF11801.8 KND98945.1 - 0.012 15.6 0.4 0.03 14.3 0.0 1.8 2 0 0 2 2 2 0 Tom37 C-terminal domain DUF4448 PF14610.6 KND98946.1 - 1.9e-59 200.6 0.5 1.9e-59 200.6 0.5 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) Zip PF02535.22 KND98948.1 - 1.6e-22 80.2 16.6 7.1e-14 51.8 5.1 2.3 1 1 1 2 2 2 2 ZIP Zinc transporter DUF2946 PF11162.8 KND98948.1 - 9.7 6.9 7.8 3.8 8.2 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) PNRC PF15365.6 KND98949.1 - 1.3e-07 31.2 4.0 1.3e-07 31.2 4.0 2.7 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif EPL1 PF10513.9 KND98949.1 - 0.046 14.1 0.6 0.068 13.6 0.6 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like Proton_antipo_M PF00361.20 KND98950.1 - 2.3e-12 46.8 4.7 2.5e-12 46.6 4.7 1.0 1 0 0 1 1 1 1 Proton-conducting membrane transporter DUF5083 PF16890.5 KND98950.1 - 0.2 11.4 3.9 0.22 11.3 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) Proton_antipo_M PF00361.20 KND98954.1 - 2.6e-19 69.5 6.6 2.6e-19 69.5 6.6 2.0 2 0 0 2 2 2 1 Proton-conducting membrane transporter NADH5_C PF06455.11 KND98954.1 - 2.3e-06 27.3 1.3 2.3e-06 27.3 1.3 2.4 2 1 1 3 3 3 1 NADH dehydrogenase subunit 5 C-terminus LAGLIDADG_1 PF00961.19 KND98955.1 - 3.3e-09 37.6 6.3 3.3e-09 37.6 6.3 2.0 1 1 1 2 2 2 1 LAGLIDADG endonuclease LAGLIDADG_3 PF14528.6 KND98955.1 - 0.0023 18.2 1.0 0.0034 17.7 0.9 1.7 1 1 0 1 1 1 1 LAGLIDADG-like domain Ca_bind_SSO6904 PF18249.1 KND98955.1 - 0.47 10.8 6.0 6.1 7.3 0.0 2.2 1 1 1 2 2 2 0 Calcium binding protein SSO6904 LAGLIDADG_1 PF00961.19 KND98956.1 - 7.1e-05 23.7 2.4 8.6e-05 23.5 2.4 1.1 1 0 0 1 1 1 1 LAGLIDADG endonuclease LAGLIDADG_1 PF00961.19 KND98957.1 - 2e-05 25.5 11.0 2.5e-05 25.2 11.0 1.2 1 0 0 1 1 1 1 LAGLIDADG endonuclease CRS1_YhbY PF01985.21 KND98959.1 - 0.0046 17.1 0.4 0.005 17.0 0.4 1.0 1 0 0 1 1 1 1 CRS1 / YhbY (CRM) domain SnoaL_3 PF13474.6 KND98964.1 - 0.18 12.1 1.0 7 6.9 0.0 3.0 3 0 0 3 3 3 0 SnoaL-like domain Nanovirus_coat PF04660.12 KND98964.1 - 0.22 11.6 6.4 8.2 6.5 0.2 3.4 4 0 0 4 4 4 0 Nanovirus coat protein ABC_tran PF00005.27 KND98968.1 - 9.2e-09 35.9 0.0 1e-08 35.8 0.0 1.0 1 0 0 1 1 1 1 ABC transporter DUF2199 PF09965.9 KND98968.1 - 0.037 14.1 0.0 0.043 13.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) Coatamer_beta_C PF07718.12 KND98976.1 - 0.45 10.4 4.9 4.7 7.1 2.8 2.7 1 1 2 3 3 3 0 Coatomer beta C-terminal region Hyr1 PF15789.5 KND98977.1 - 3e-90 295.5 502.9 4.2e-09 35.8 13.0 28.5 28 3 0 28 28 28 24 Hyphally regulated cell wall GPI-anchored protein 1 Imm53 PF15580.6 KND98977.1 - 3e-14 52.5 47.0 6.2 6.6 0.0 20.3 21 1 0 21 21 21 4 Immunity protein 53 DUF3872 PF12988.7 KND98977.1 - 3.2e-06 27.0 2.3 9 6.1 0.1 9.0 6 1 2 10 10 10 1 Domain of unknown function, B. Theta Gene description (DUF3872) LpxD PF04613.14 KND98977.1 - 0.00025 20.7 14.4 4.3 7.2 0.0 11.7 18 0 0 18 18 18 1 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD FTP PF07504.13 KND98977.1 - 0.038 13.8 82.1 3 7.8 0.3 22.3 24 1 1 25 25 25 0 Fungalysin/Thermolysin Propeptide Motif PPV_E2_C PF00511.17 KND98977.1 - 0.16 12.2 133.9 2.8 8.2 1.0 21.5 4 4 18 22 22 22 0 E2 (early) protein, C terminal ABC_trans_aux PF03886.13 KND98977.1 - 4.1 7.0 6.8 15 5.1 0.3 3.9 3 0 0 3 3 3 0 ABC-type transport auxiliary lipoprotein component Hyphal_reg_CWP PF11765.8 KND98979.1 - 5e-74 249.2 7.7 6.7e-74 248.8 7.7 1.2 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Hyr1 PF15789.5 KND98979.1 - 0.013 15.0 6.1 0.013 15.0 6.1 4.6 4 1 0 4 4 4 0 Hyphally regulated cell wall GPI-anchored protein 1 LIP PF03583.14 KND98980.1 - 3.3e-90 302.3 0.0 1.5e-89 300.2 0.0 1.9 2 0 0 2 2 2 1 Secretory lipase Peptidase_S9 PF00326.21 KND98980.1 - 0.01 15.3 0.0 0.88 9.0 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KND98980.1 - 0.011 15.3 0.2 0.019 14.6 0.2 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Proton_antipo_N PF00662.20 KND98982.1 - 2 8.6 8.5 1.6 8.8 0.5 2.3 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus DUF2299 PF10061.9 KND98982.1 - 3.5 7.4 10.3 6.2 6.6 1.7 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2299) MFS_1 PF07690.16 KND98987.1 - 1e-27 97.0 17.7 1e-27 97.0 17.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND98987.1 - 7.2e-08 31.7 8.8 2.8e-07 29.8 6.8 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KND98987.1 - 0.00068 18.2 1.2 0.001 17.6 1.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Branch PF02485.21 KND98988.1 - 0.038 13.5 0.0 0.039 13.4 0.0 1.1 1 0 0 1 1 1 0 Core-2/I-Branching enzyme adh_short_C2 PF13561.6 KND98989.1 - 3e-54 184.1 0.8 4e-54 183.6 0.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND98989.1 - 1.3e-50 171.6 1.2 1.6e-50 171.3 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND98989.1 - 5.4e-11 42.7 1.2 8e-11 42.2 1.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KND98989.1 - 1.6e-05 24.5 0.0 0.00034 20.1 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Transketolase_C PF02780.20 KND98989.1 - 0.0023 17.8 0.1 0.005 16.7 0.1 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Peripla_BP_6 PF13458.6 KND98989.1 - 0.041 13.6 0.5 0.083 12.5 0.5 1.5 1 1 0 1 1 1 0 Periplasmic binding protein Pro_isomerase PF00160.21 KND98990.1 - 2.5e-48 164.3 1.0 3.1e-48 164.0 0.1 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KND98990.1 - 0.0073 16.3 0.2 0.0073 16.3 0.2 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KND98990.1 - 0.046 13.5 0.2 0.046 13.5 0.2 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KND98990.1 - 0.054 13.7 0.1 0.054 13.7 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 KND98991.1 - 3.3e-61 207.0 0.1 3.9e-61 206.7 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND98991.1 - 6.9e-16 58.3 0.0 1.3e-15 57.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KND98991.1 - 1.2e-05 25.4 0.0 0.00015 21.8 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KND98991.1 - 0.026 13.3 0.0 0.042 12.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 KND98991.1 - 0.046 13.3 0.2 0.083 12.5 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase ABC1 PF03109.16 KND98991.1 - 0.056 13.6 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 ABC1 family DED PF01335.21 KND98991.1 - 0.61 10.4 2.2 4.2 7.7 0.0 2.6 3 0 0 3 3 3 0 Death effector domain LTV PF04180.14 KND98992.1 - 3e-108 363.0 29.3 3.5e-108 362.8 29.3 1.0 1 0 0 1 1 1 1 Low temperature viability protein MatE PF01554.18 KND98993.1 - 9.8e-56 187.9 35.0 5.8e-31 107.3 9.1 3.4 4 0 0 4 4 4 2 MatE Polysacc_synt_C PF14667.6 KND98993.1 - 1.2e-05 25.4 11.3 1.2e-05 25.4 11.3 4.6 3 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain PIH1 PF08190.12 KND98995.1 - 1.7e-21 76.4 0.1 3.2e-21 75.5 0.1 1.4 1 0 0 1 1 1 1 PIH1 N-terminal domain Pih1_fungal_CS PF18482.1 KND98995.1 - 0.0006 20.3 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 Fungal Pih1 CS domain BPL_N PF09825.9 KND98996.1 - 1.1e-128 429.5 0.0 1.5e-128 429.1 0.0 1.2 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KND98996.1 - 6.2e-16 58.5 0.0 1e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 KND98996.1 - 1.8e-08 34.1 0.1 3.4e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain zf-ANAPC11 PF12861.7 KND98997.1 - 9.6e-44 147.4 8.2 1.2e-43 147.1 8.2 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KND98997.1 - 3.3e-21 75.3 9.1 5.4e-21 74.6 9.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KND98997.1 - 4.5e-07 30.1 15.7 8.2e-06 26.1 15.6 2.6 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KND98997.1 - 0.00055 19.7 6.2 0.00055 19.7 6.2 2.5 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KND98997.1 - 0.0089 16.2 1.0 0.0089 16.2 1.0 2.2 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KND98997.1 - 0.011 15.6 11.0 0.036 13.8 0.7 3.1 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 KND98997.1 - 0.014 15.3 13.6 0.073 12.9 13.6 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KND98997.1 - 0.015 15.3 12.2 0.019 15.0 7.2 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-PHD-like PF15446.6 KND98997.1 - 0.027 14.1 1.2 0.041 13.5 1.2 1.3 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-HIT PF04438.16 KND98997.1 - 0.067 13.1 1.5 0.067 13.1 1.5 2.2 2 0 0 2 2 2 0 HIT zinc finger PHD PF00628.29 KND98997.1 - 0.38 10.7 10.1 1.1 9.2 10.1 1.8 1 1 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 KND98997.1 - 0.56 9.9 9.8 9.5 5.9 9.8 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KND98997.1 - 0.74 9.6 9.4 5.1 6.9 9.4 2.3 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 KND98997.1 - 0.98 9.4 12.5 4.2 7.4 12.6 2.2 1 1 1 2 2 2 0 zinc-RING finger domain RINGv PF12906.7 KND98997.1 - 2.5 8.3 11.5 0.12 12.5 4.7 2.1 2 0 0 2 2 2 0 RING-variant domain zf-Di19 PF05605.12 KND98997.1 - 3 8.2 9.8 3.1e+02 1.7 7.3 3.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_3 PF13920.6 KND98997.1 - 3.4 7.6 12.5 7.2 6.6 7.9 2.6 1 1 2 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KND98997.1 - 4.2 7.8 9.9 26 5.2 9.9 2.3 1 1 1 2 2 2 0 RING-like domain zinc_ribbon_9 PF14369.6 KND98997.1 - 4.5 7.6 9.3 3.5 8.0 0.1 3.2 2 1 0 2 2 2 0 zinc-ribbon UbiA PF01040.18 KND98999.1 - 1.4e-47 162.2 18.1 1.7e-47 161.8 18.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family CNH PF00780.22 KND99000.1 - 0.0021 17.8 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 CNH domain Vps39_2 PF10367.9 KND99000.1 - 0.0041 17.5 0.1 0.022 15.2 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 AA_kinase PF00696.28 KND99001.1 - 5e-35 121.2 1.1 8.2e-35 120.5 1.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KND99001.1 - 4e-15 55.5 0.4 8.5e-15 54.5 0.1 1.8 2 0 0 2 2 2 1 PUA domain RF-1 PF00472.20 KND99002.1 - 6.2e-25 87.4 3.3 9.2e-25 86.8 3.3 1.3 1 0 0 1 1 1 1 RF-1 domain SOUL PF04832.12 KND99002.1 - 0.0081 16.4 0.0 0.012 15.8 0.0 1.4 1 1 0 1 1 1 1 SOUL heme-binding protein DUF2439 PF10382.9 KND99002.1 - 0.59 10.5 4.6 20 5.6 3.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2439) Lipase_GDSL_2 PF13472.6 KND99004.1 - 1.3e-24 87.6 0.0 2.9e-24 86.5 0.0 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KND99004.1 - 2.1e-15 57.3 0.0 2.8e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Cellulase PF00150.18 KND99004.1 - 0.01 15.3 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) DUF1574 PF07611.11 KND99004.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) Carb_kinase PF01256.17 KND99004.1 - 0.24 10.8 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate kinase ABC_tran PF00005.27 KND99005.1 - 2.9e-49 167.1 0.1 4.7e-24 85.5 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KND99005.1 - 4.6e-22 77.8 0.8 4.6e-22 77.8 0.8 3.4 4 1 0 4 4 2 1 ABC transporter AAA_21 PF13304.6 KND99005.1 - 5e-19 69.2 0.8 1.4e-05 25.1 0.1 4.2 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KND99005.1 - 8.2e-11 41.8 0.5 0.18 11.2 0.0 4.4 3 1 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KND99005.1 - 3.3e-09 37.4 0.6 8e-05 23.1 0.0 2.8 3 0 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.6 KND99005.1 - 6e-08 32.3 0.0 0.0023 17.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KND99005.1 - 8e-07 29.1 0.5 0.004 17.1 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase AAA_22 PF13401.6 KND99005.1 - 8.6e-07 29.3 0.4 0.047 14.0 0.1 3.1 3 1 0 3 3 2 2 AAA domain AAA_28 PF13521.6 KND99005.1 - 4.2e-06 27.1 0.0 0.015 15.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KND99005.1 - 1.7e-05 25.4 0.0 0.07 13.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 KND99005.1 - 2.8e-05 24.1 0.5 0.16 11.9 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_23 PF13476.6 KND99005.1 - 3.7e-05 24.3 10.8 0.061 13.8 0.0 4.2 4 0 0 4 4 3 2 AAA domain AAA_5 PF07728.14 KND99005.1 - 4.3e-05 23.5 0.1 0.32 11.0 0.1 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 KND99005.1 - 4.6e-05 23.5 0.0 0.2 11.8 0.0 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase RNA_helicase PF00910.22 KND99005.1 - 4.8e-05 23.7 0.1 0.72 10.3 0.0 3.1 3 0 0 3 3 2 2 RNA helicase AAA_33 PF13671.6 KND99005.1 - 7.5e-05 22.9 0.5 0.44 10.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.6 KND99005.1 - 0.00011 22.3 0.0 0.73 9.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain Roc PF08477.13 KND99005.1 - 0.00016 21.8 0.0 0.21 11.8 0.1 2.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 KND99005.1 - 0.00018 21.4 8.4 0.035 13.8 0.0 3.9 4 1 0 5 5 5 2 AAA ATPase domain AAA_24 PF13479.6 KND99005.1 - 0.00029 20.6 0.6 0.29 10.8 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 KND99005.1 - 0.00036 20.9 0.0 1.5 9.2 0.1 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KND99005.1 - 0.00059 19.5 0.1 2.9 7.4 0.0 4.1 4 1 1 5 5 5 1 AAA domain NB-ARC PF00931.22 KND99005.1 - 0.00062 19.0 0.0 0.86 8.7 0.1 3.2 3 0 0 3 3 3 1 NB-ARC domain AAA_7 PF12775.7 KND99005.1 - 0.0014 18.1 0.0 0.29 10.7 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 KND99005.1 - 0.0017 17.6 0.2 1.4 8.1 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF815) Rad17 PF03215.15 KND99005.1 - 0.0021 18.0 0.0 2.4 8.1 0.0 2.6 3 0 0 3 3 2 1 Rad17 P-loop domain MCM PF00493.23 KND99005.1 - 0.005 16.0 0.0 1.2 8.2 0.0 2.3 2 0 0 2 2 2 1 MCM P-loop domain PduV-EutP PF10662.9 KND99005.1 - 0.0061 16.3 0.4 13 5.5 0.0 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 KND99005.1 - 0.0078 15.4 0.2 5.3 6.1 0.0 3.0 3 1 1 4 4 4 0 G-protein alpha subunit Septin PF00735.18 KND99005.1 - 0.011 15.0 0.0 2 7.6 0.0 2.5 2 0 0 2 2 2 0 Septin Ras PF00071.22 KND99005.1 - 0.012 15.2 0.1 4.5 6.8 0.0 2.7 3 0 0 3 3 2 0 Ras family DAP3 PF10236.9 KND99005.1 - 0.047 12.8 0.3 5.9 6.0 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NTPase_1 PF03266.15 KND99005.1 - 0.052 13.5 0.1 2.3 8.1 0.1 2.5 2 0 0 2 2 2 0 NTPase TniB PF05621.11 KND99005.1 - 0.064 12.7 0.1 5 6.5 0.0 3.0 3 1 0 3 3 3 0 Bacterial TniB protein MeaB PF03308.16 KND99005.1 - 0.066 12.2 0.1 9.8 5.1 0.0 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Mrr_cat PF04471.12 KND99005.1 - 0.088 12.8 0.7 0.7 9.9 0.0 2.7 3 0 0 3 3 2 0 Restriction endonuclease DUF2813 PF11398.8 KND99005.1 - 0.11 11.7 0.7 5.3 6.2 0.0 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF2813) ATPase_2 PF01637.18 KND99005.1 - 0.12 12.3 4.8 4.2 7.2 0.0 3.3 4 0 0 4 4 3 0 ATPase domain predominantly from Archaea DUF87 PF01935.17 KND99005.1 - 0.56 10.3 4.9 12 5.9 0.0 3.4 3 1 0 4 4 3 0 Helicase HerA, central domain AAA_30 PF13604.6 KND99005.1 - 0.7 9.6 8.1 0.61 9.8 0.1 3.9 4 1 0 4 4 4 0 AAA domain AAA_17 PF13207.6 KND99005.1 - 1.3 9.5 6.7 26 5.3 0.0 3.9 4 0 0 4 4 3 0 AAA domain DLIC PF05783.11 KND99005.1 - 2.3 7.0 6.3 1.1 8.1 0.0 2.8 4 0 0 4 4 3 0 Dynein light intermediate chain (DLIC) Dynamin_N PF00350.23 KND99005.1 - 2.9 7.9 7.1 20 5.2 0.0 3.8 3 1 1 4 4 4 0 Dynamin family Utp12 PF04003.12 KND99006.1 - 8.8e-14 51.7 2.2 1.7e-13 50.8 2.2 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Pribosyltran PF00156.27 KND99007.1 - 4.7e-10 39.2 0.0 6.5e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Syntaxin-6_N PF09177.11 KND99007.1 - 0.0019 18.7 0.1 0.0036 17.8 0.1 1.4 1 0 0 1 1 1 1 Syntaxin 6, N-terminal IBN_N PF03810.19 KND99010.1 - 3.9e-16 58.7 0.0 1.5e-15 56.8 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KND99010.1 - 5.6e-06 26.5 1.1 2.6e-05 24.3 0.1 2.7 2 0 0 2 2 2 1 Exportin 1-like protein Cse1 PF08506.10 KND99010.1 - 2.1e-05 23.5 0.1 6.7e-05 21.9 0.0 1.8 2 0 0 2 2 2 1 Cse1 Glypican PF01153.19 KND99010.1 - 0.13 11.0 0.8 9.7 4.9 0.1 2.3 2 0 0 2 2 2 0 Glypican DUF4375 PF14300.6 KND99010.1 - 0.2 12.0 2.9 0.79 10.0 0.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4375) Clathrin_lg_ch PF01086.17 KND99010.1 - 0.28 11.2 4.0 20 5.2 3.9 2.3 2 0 0 2 2 2 0 Clathrin light chain BLM10_mid PF16507.5 KND99011.1 - 1.2e-167 558.7 0.0 1.2e-167 558.7 0.0 2.7 3 0 0 3 3 3 1 Proteasome-substrate-size regulator, mid region BLM10_N PF16547.5 KND99011.1 - 7.2e-30 103.1 0.1 3.7e-29 100.8 0.1 2.4 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal DUF3437 PF11919.8 KND99011.1 - 2.3e-25 88.3 0.0 1e-24 86.2 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) TMF_TATA_bd PF12325.8 KND99012.1 - 8.4e-28 96.9 18.3 8.4e-28 96.9 18.3 6.9 2 1 3 6 6 6 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KND99012.1 - 3.1e-12 46.3 13.5 3.1e-12 46.3 13.5 10.2 5 4 3 9 9 9 3 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 KND99012.1 - 0.0035 17.5 8.1 0.0035 17.5 8.1 5.6 2 1 3 5 5 5 1 Uncharacterised protein family (UPF0242) N-terminus DUF2746 PF10874.8 KND99012.1 - 1.1 9.8 3.5 45 4.5 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2746) DrsE_2 PF13686.6 KND99012.1 - 8.8 6.2 10.6 0.27 11.1 3.2 2.4 2 0 0 2 2 2 0 DsrE/DsrF/DrsH-like family Ig_mannosidase PF17753.1 KND99023.1 - 0.063 13.0 0.0 0.083 12.7 0.0 1.1 1 0 0 1 1 1 0 Ig-fold domain F-box-like PF12937.7 KND99029.1 - 0.0091 15.9 0.1 0.026 14.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like Pox_D2 PF04701.13 KND99029.1 - 0.049 13.8 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 Pox virus D2 protein LRR_11 PF18831.1 KND99031.1 - 0.12 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeat Sec2p PF06428.11 KND99033.1 - 3.9e-20 71.6 12.8 3.9e-20 71.6 12.8 3.7 2 2 1 3 3 3 1 GDP/GTP exchange factor Sec2p Tropomyosin_1 PF12718.7 KND99033.1 - 0.00032 20.9 18.6 0.00032 20.9 18.6 3.7 2 2 1 3 3 3 1 Tropomyosin like GAS PF13851.6 KND99033.1 - 0.0015 17.9 14.6 0.0015 17.9 14.6 3.5 2 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding SlyX PF04102.12 KND99033.1 - 0.045 14.4 0.9 0.045 14.4 0.9 4.7 3 1 1 4 4 4 0 SlyX Las1 PF04031.13 KND99033.1 - 0.055 13.6 0.1 0.15 12.2 0.1 1.7 1 0 0 1 1 1 0 Las1-like FUSC PF04632.12 KND99033.1 - 0.57 8.6 8.8 0.033 12.8 3.4 1.5 2 0 0 2 2 2 0 Fusaric acid resistance protein family Mrx7 PF10906.8 KND99033.1 - 0.58 10.4 4.2 6.4 7.1 0.4 3.3 2 0 0 2 2 2 0 MIOREX complex component 7 Exonuc_VII_L PF02601.15 KND99033.1 - 2.4 7.7 18.8 0.39 10.3 7.7 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF3584 PF12128.8 KND99033.1 - 4.8 4.6 41.2 0.11 10.0 19.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) FH2 PF02181.23 KND99036.1 - 2.2e-88 296.9 8.5 2.2e-88 296.9 8.5 3.2 4 0 0 4 4 4 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 KND99036.1 - 2.1e-47 161.3 0.3 2.1e-47 161.3 0.3 4.7 5 1 1 6 6 6 2 Diaphanous FH3 Domain Drf_GBD PF06371.13 KND99036.1 - 1.1e-34 119.6 0.4 1.1e-34 119.6 0.4 3.5 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain MMS1_N PF10433.9 KND99037.1 - 3.3e-32 111.8 0.0 7.8e-32 110.5 0.0 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DNA_gyraseA_C PF03989.13 KND99037.1 - 0.02 14.4 0.1 1.3 8.6 0.0 2.8 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller Sugar_tr PF00083.24 KND99040.1 - 8e-08 31.6 20.1 1.2e-07 31.0 20.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Yip1 PF04893.17 KND99041.1 - 1.1e-13 51.2 6.0 1.1e-13 51.2 6.0 1.3 2 0 0 2 2 2 1 Yip1 domain DUF3784 PF12650.7 KND99041.1 - 3.7 7.8 9.3 0.29 11.4 2.9 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3784) Pkinase PF00069.25 KND99042.1 - 1.2e-55 188.7 0.0 1.4e-55 188.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND99042.1 - 1.3e-33 116.4 0.0 1.4e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND99042.1 - 6.3e-05 22.4 0.0 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KND99042.1 - 0.083 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PPR_2 PF13041.6 KND99043.1 - 7.8e-08 32.4 2.9 0.036 14.3 0.0 4.8 5 0 0 5 5 5 2 PPR repeat family PPR PF01535.20 KND99043.1 - 0.00072 19.6 3.2 22 5.6 0.0 5.9 6 0 0 6 6 6 2 PPR repeat PPR_long PF17177.4 KND99043.1 - 0.0031 16.9 0.8 3.2 7.1 0.0 3.6 4 0 0 4 4 4 2 Pentacotripeptide-repeat region of PRORP DUF3106 PF11304.8 KND99043.1 - 0.086 13.3 0.7 1.3 9.6 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) SPC22 PF04573.12 KND99044.1 - 1.4e-57 193.9 0.3 1.6e-57 193.7 0.3 1.0 1 0 0 1 1 1 1 Signal peptidase subunit LtrA PF06772.11 KND99044.1 - 0.058 12.6 0.6 0.074 12.3 0.6 1.1 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) tRNA-synt_1e PF01406.19 KND99045.1 - 4.3e-133 443.3 0.2 4.3e-133 443.3 0.2 2.0 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KND99045.1 - 3.1e-10 39.3 1.8 2.5e-05 23.2 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 KND99045.1 - 8.5e-05 21.6 0.1 0.0024 16.9 0.1 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 KND99045.1 - 9.2e-05 20.9 6.8 0.00026 19.4 0.0 3.1 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) Glu-tRNAGln PF02686.15 KND99045.1 - 0.11 12.8 0.0 5.9 7.3 0.0 3.3 3 1 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit GTP_EFTU PF00009.27 KND99049.1 - 1.4e-62 210.7 0.2 2.7e-62 209.8 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KND99049.1 - 2.6e-33 114.3 0.1 7.1e-33 113.0 0.1 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 KND99049.1 - 3.1e-29 100.9 0.0 6.5e-29 99.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KND99049.1 - 1.7e-22 79.3 0.1 3.7e-22 78.2 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KND99049.1 - 3.7e-11 43.2 0.1 1.1e-10 41.7 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KND99049.1 - 2e-07 30.9 0.0 4.6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KND99049.1 - 0.01 15.9 0.0 0.035 14.2 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase AvrPtoB_bdg PF16847.5 KND99049.1 - 0.011 16.2 0.0 1.9 9.1 0.0 2.6 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain SLATT_4 PF18186.1 KND99050.1 - 0.042 13.5 1.6 19 4.8 0.0 3.3 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 4 FA_desaturase PF00487.24 KND99052.1 - 1.2e-24 87.6 22.6 1.7e-24 87.1 22.6 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KND99052.1 - 7.5e-05 22.9 0.0 0.00014 22.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Chitin_synth_2 PF03142.15 KND99054.1 - 3.2e-272 903.8 0.4 3.2e-272 903.8 0.4 1.5 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KND99054.1 - 1.8e-12 47.6 3.6 8.6e-12 45.4 3.6 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KND99054.1 - 4.2e-10 39.9 0.0 2.6e-08 34.1 0.0 2.4 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KND99054.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KND99054.1 - 0.014 15.2 0.0 0.38 10.6 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 Cyt-b5 PF00173.28 KND99054.1 - 0.13 12.5 0.0 0.48 10.6 0.0 2.0 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Sec7_N PF12783.7 KND99056.1 - 8e-30 103.8 0.6 8e-30 103.8 0.6 3.8 4 1 1 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KND99056.1 - 6.4e-21 74.8 0.7 6.4e-21 74.8 0.7 3.9 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 KND99056.1 - 8.9e-14 50.6 0.2 2.3e-13 49.3 0.1 1.8 2 0 0 2 2 2 1 C-terminal region of Mon2 protein DUF1981 PF09324.10 KND99056.1 - 0.031 14.1 0.5 2.2 8.2 0.0 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) Heme_oxygenase PF01126.20 KND99059.1 - 2.3e-22 79.8 3.6 4.3e-22 78.9 3.6 1.4 1 1 0 1 1 1 1 Heme oxygenase Ribosomal_S6 PF01250.17 KND99059.1 - 0.053 13.8 0.1 0.17 12.2 0.1 1.9 2 0 0 2 2 2 0 Ribosomal protein S6 AAA_18 PF13238.6 KND99060.1 - 7.7e-27 94.4 0.2 7.7e-27 94.4 0.2 2.3 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.6 KND99060.1 - 2e-05 25.0 0.0 2e-05 25.0 0.0 2.3 1 1 2 3 3 3 1 AAA domain AAA_22 PF13401.6 KND99060.1 - 0.00015 22.0 0.0 0.00036 20.8 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 KND99060.1 - 0.00022 21.4 0.1 0.012 15.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KND99060.1 - 0.00051 20.5 1.6 0.0014 19.1 1.6 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KND99060.1 - 0.00066 19.7 0.0 0.0015 18.6 0.0 1.6 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KND99060.1 - 0.00072 19.8 0.0 0.00072 19.8 0.0 2.5 3 1 0 3 3 2 1 AAA domain Viral_helicase1 PF01443.18 KND99060.1 - 0.00091 19.0 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA PF00004.29 KND99060.1 - 0.00093 19.6 0.0 0.0025 18.2 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KND99060.1 - 0.0013 18.2 0.0 0.0029 17.1 0.0 1.5 2 0 0 2 2 1 1 P-loop containing dynein motor region KTI12 PF08433.10 KND99060.1 - 0.0021 17.6 0.2 0.0059 16.1 0.0 1.8 2 0 0 2 2 2 1 Chromatin associated protein KTI12 RNA_helicase PF00910.22 KND99060.1 - 0.0025 18.2 0.1 0.0071 16.7 0.0 1.8 2 0 0 2 2 2 1 RNA helicase Na_trans_assoc PF06512.13 KND99060.1 - 0.0033 17.7 18.5 0.0045 17.3 18.5 1.2 1 0 0 1 1 1 1 Sodium ion transport-associated NTPase_1 PF03266.15 KND99060.1 - 0.0037 17.2 0.2 0.012 15.5 0.0 1.9 2 0 0 2 2 2 1 NTPase PPP4R2 PF09184.11 KND99060.1 - 0.0046 16.6 20.2 0.0053 16.4 20.2 1.2 1 0 0 1 1 1 1 PPP4R2 Mg_chelatase PF01078.21 KND99060.1 - 0.0049 16.3 0.0 0.0077 15.6 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KND99060.1 - 0.0064 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 KND99060.1 - 0.01 15.8 0.2 0.061 13.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KND99060.1 - 0.013 14.6 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein CDC45 PF02724.14 KND99060.1 - 0.016 13.6 19.5 0.018 13.4 19.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SRPRB PF09439.10 KND99060.1 - 0.027 13.9 0.3 0.099 12.1 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KND99060.1 - 0.063 13.8 0.7 0.13 12.8 0.6 1.8 1 1 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 KND99060.1 - 0.094 13.0 0.0 0.23 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KND99060.1 - 0.1 12.7 0.2 0.28 11.3 0.2 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KND99060.1 - 0.11 11.8 0.3 0.23 10.8 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.17 KND99060.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_polI_A34 PF08208.11 KND99060.1 - 3.6 7.6 18.5 5.9 6.9 18.5 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 AAA_11 PF13086.6 KND99060.1 - 4.4 7.0 0.0 4.4 7.0 0.0 2.4 2 1 0 2 2 1 0 AAA domain DUF4746 PF15928.5 KND99060.1 - 6 6.2 23.8 8.7 5.7 23.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RNA_pol_Rpc4 PF05132.14 KND99060.1 - 6.7 7.1 9.2 9.5 6.6 9.2 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 SDA1 PF05285.12 KND99060.1 - 9.1 5.6 36.4 13 5.1 36.4 1.2 1 0 0 1 1 1 0 SDA1 Cytomega_UL20A PF05984.12 KND99061.1 - 0.17 12.2 0.0 0.23 11.8 0.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein RSN1_TM PF13967.6 KND99061.1 - 0.18 11.6 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport DUF347 PF03988.12 KND99063.1 - 0.034 14.3 2.4 0.074 13.3 2.4 1.5 1 1 0 1 1 1 0 Repeat of Unknown Function (DUF347) DUF2615 PF11027.8 KND99063.1 - 0.15 12.2 0.0 0.16 12.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Aa_trans PF01490.18 KND99066.1 - 6.8e-30 104.1 37.8 8.2e-30 103.8 37.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2976 PF11190.8 KND99066.1 - 0.42 10.4 7.3 0.68 9.8 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) Tyr_Deacylase PF02580.16 KND99067.1 - 1.9e-51 174.4 0.0 2.1e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase LIP PF03583.14 KND99069.1 - 1.9e-95 319.5 0.0 5.3e-95 318.0 0.0 1.6 2 0 0 2 2 2 1 Secretory lipase Hydrolase_4 PF12146.8 KND99069.1 - 0.013 14.8 0.0 0.11 11.7 0.0 2.2 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KND99069.1 - 0.031 13.9 0.0 0.77 9.4 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KND99069.1 - 0.033 13.7 0.5 2.6 7.4 0.0 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase family SecY PF00344.20 KND99070.1 - 8.5e-47 159.9 8.4 1.1e-46 159.6 8.4 1.1 1 0 0 1 1 1 1 SecY translocase DMRL_synthase PF00885.19 KND99072.1 - 6.3e-54 181.6 0.0 7.4e-54 181.4 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase zf-CHY PF05495.12 KND99076.1 - 5.3e-16 58.9 11.6 9.6e-16 58.0 11.6 1.4 1 0 0 1 1 1 1 CHY zinc finger p450 PF00067.22 KND99077.1 - 3e-61 207.6 0.0 4e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cyclin_N PF00134.23 KND99078.1 - 1e-42 144.9 0.5 1.9e-42 144.0 0.5 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KND99078.1 - 3.5e-37 127.1 0.1 9e-37 125.8 0.1 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain MAM33 PF02330.16 KND99079.1 - 3.3e-41 141.6 8.6 3.9e-41 141.3 8.6 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF1889 PF08986.10 KND99079.1 - 0.1 13.0 0.0 0.62 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1889) RRM_1 PF00076.22 KND99080.1 - 4.5e-79 260.2 8.1 3.1e-19 68.6 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KND99080.1 - 1.8e-12 46.9 0.0 0.00074 19.1 0.0 5.0 4 1 1 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KND99080.1 - 3.9e-09 36.4 1.9 0.35 10.9 0.0 5.8 6 0 0 6 6 6 4 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KND99080.1 - 4.5e-09 36.0 0.8 0.029 14.2 0.0 5.5 5 1 1 6 6 6 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KND99080.1 - 0.0024 17.9 0.1 0.42 10.7 0.0 3.4 3 0 0 3 3 3 1 Limkain b1 Acyltransferase PF01553.21 KND99081.1 - 0.0042 16.7 0.0 0.011 15.3 0.0 1.7 1 1 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KND99081.1 - 0.055 13.6 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 Acyltransferase C-terminus AAA_23 PF13476.6 KND99082.1 - 1.5e-30 107.2 0.4 1.5e-30 107.2 0.4 8.8 2 1 3 5 5 1 1 AAA domain AAA_15 PF13175.6 KND99082.1 - 3.7e-09 36.8 6.4 3.7e-09 36.8 6.4 5.4 1 1 3 4 4 2 1 AAA ATPase domain AAA_21 PF13304.6 KND99082.1 - 3.1e-07 30.5 10.3 0.0012 18.7 0.0 4.2 4 2 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KND99082.1 - 2.1e-05 24.7 0.0 7.4e-05 22.9 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 KND99082.1 - 9e-05 22.0 0.0 9e-05 22.0 0.0 3.7 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain Rad50_zn_hook PF04423.14 KND99082.1 - 0.00059 19.6 0.1 0.00059 19.6 0.1 6.9 9 0 0 9 9 8 1 Rad50 zinc hook motif Spc7 PF08317.11 KND99082.1 - 0.0028 16.6 10.6 0.0028 16.6 10.6 8.2 2 2 6 8 8 8 4 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KND99082.1 - 0.006 16.6 23.0 0.006 16.6 23.0 11.1 4 3 5 9 9 7 1 TPR/MLP1/MLP2-like protein GAS PF13851.6 KND99082.1 - 0.0067 15.8 4.0 0.0067 15.8 4.0 9.5 3 2 5 9 9 9 3 Growth-arrest specific micro-tubule binding GP57 PF17594.2 KND99082.1 - 0.013 15.3 1.8 2 8.2 0.1 3.8 2 0 0 2 2 2 0 Phage Tail fiber assembly helper gene product 57 AAA_29 PF13555.6 KND99082.1 - 0.014 15.2 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KND99082.1 - 0.14 12.6 0.0 0.14 12.6 0.0 5.5 4 2 0 4 4 2 0 AAA ATPase domain WD40_alt PF14077.6 KND99082.1 - 0.15 11.9 3.0 6 6.8 0.2 4.8 4 0 0 4 4 4 0 Alternative WD40 repeat motif AAA_22 PF13401.6 KND99082.1 - 0.26 11.6 0.1 0.26 11.6 0.1 5.7 4 2 1 5 5 4 0 AAA domain AAA PF00004.29 KND99082.1 - 0.6 10.5 4.3 10 6.5 0.2 4.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 KND99082.1 - 0.69 8.5 0.0 0.11 11.1 24.1 7.2 3 1 5 8 8 6 0 AAA domain MtrG PF04210.13 KND99082.1 - 0.74 9.7 4.7 26 4.8 0.1 4.9 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF4407 PF14362.6 KND99082.1 - 0.98 8.7 109.2 0.34 10.2 10.2 6.7 2 2 5 7 7 7 0 Domain of unknown function (DUF4407) zf-C2H2 PF00096.26 KND99083.1 - 9.2e-22 76.2 28.1 1.6e-06 28.3 0.4 4.9 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KND99083.1 - 1.5e-21 75.8 29.2 4.1e-09 36.5 0.7 4.8 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KND99083.1 - 3.4e-14 52.3 22.5 0.00032 21.3 0.3 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 KND99083.1 - 2.9e-05 24.3 14.7 0.00066 20.0 0.3 4.6 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KND99083.1 - 0.00045 20.2 25.2 0.00065 19.6 1.0 5.0 5 0 0 5 5 5 2 C2H2-type zinc finger zf-Di19 PF05605.12 KND99083.1 - 0.0016 18.7 7.9 0.038 14.3 0.6 2.5 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KND99083.1 - 0.0099 16.1 10.4 0.054 13.8 0.0 3.8 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KND99083.1 - 0.18 12.1 11.3 13 6.2 0.1 3.7 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KND99083.1 - 0.33 10.8 3.2 4.5 7.2 0.1 3.2 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 KND99083.1 - 2.5 8.1 13.5 1.5 8.8 0.2 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type SID PF11778.8 KND99084.1 - 4.9e-06 26.7 0.3 1.4e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 Septation initiation YabA PF06156.13 KND99084.1 - 0.61 10.7 6.5 0.09 13.4 1.1 2.3 2 1 0 2 2 2 0 Initiation control protein YabA RNA_pol_L_2 PF13656.6 KND99085.1 - 5.8e-34 115.7 0.1 9e-34 115.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KND99085.1 - 2.7e-16 58.7 0.0 3.8e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DEAD PF00270.29 KND99086.1 - 1.2e-50 171.8 0.0 5.8e-50 169.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND99086.1 - 2.6e-14 53.5 0.0 1.7e-13 50.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND99086.1 - 1.4e-05 25.2 0.0 2.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KND99086.1 - 0.00028 21.3 0.0 1.1 9.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KND99086.1 - 0.014 15.1 0.0 0.27 11.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain HLH PF00010.26 KND99088.1 - 3.9e-15 55.5 0.4 7.1e-15 54.7 0.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SR-25 PF10500.9 KND99088.1 - 7.4e-05 22.5 8.7 9.4e-05 22.1 8.7 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Bul1_C PF04426.12 KND99088.1 - 0.00056 19.4 5.3 0.00081 18.9 5.3 1.3 1 0 0 1 1 1 1 Bul1 C terminus IMUP PF15761.5 KND99088.1 - 0.28 11.9 8.6 0.4 11.4 8.6 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein Phage-tail_1 PF09097.10 KND99091.1 - 0.21 11.4 0.1 0.24 11.2 0.1 1.1 1 0 0 1 1 1 0 Baseplate structural protein, domain 1 LIP PF03583.14 KND99093.1 - 3.3e-96 322.0 0.2 6.3e-96 321.0 0.0 1.5 2 0 0 2 2 2 1 Secretory lipase Peptidase_S9 PF00326.21 KND99093.1 - 0.012 15.1 0.5 1.1 8.7 0.0 2.6 3 0 0 3 3 3 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KND99093.1 - 0.017 14.4 0.0 0.17 11.1 0.0 2.1 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KND99093.1 - 0.026 14.2 0.0 0.76 9.4 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Cutinase PF01083.22 KND99093.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Cutinase Transp_inhibit PF18791.1 KND99093.1 - 0.15 11.6 0.5 0.66 9.5 0.1 2.3 2 0 0 2 2 2 0 Transport inhibitor response 1 protein domain LIP PF03583.14 KND99095.1 - 6.1e-94 314.5 0.2 1.2e-93 313.6 0.0 1.5 2 0 0 2 2 2 1 Secretory lipase Peptidase_S9 PF00326.21 KND99095.1 - 0.0038 16.7 1.4 0.7 9.3 0.0 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KND99095.1 - 0.084 12.1 0.0 0.57 9.4 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 LIP PF03583.14 KND99098.1 - 7.2e-84 281.5 0.1 1.1e-83 280.9 0.1 1.2 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 KND99098.1 - 0.016 14.7 0.4 0.35 10.3 0.0 2.6 2 1 1 3 3 3 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KND99098.1 - 0.13 11.5 0.0 0.35 10.1 0.0 1.8 1 1 0 1 1 1 0 Serine aminopeptidase, S33 LIP PF03583.14 KND99100.1 - 6.5e-96 321.0 0.0 8.6e-96 320.6 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 KND99100.1 - 0.0039 16.7 0.8 0.93 8.9 0.0 2.6 2 1 0 2 2 2 2 Prolyl oligopeptidase family LIP PF03583.14 KND99102.1 - 1.4e-86 290.4 0.0 1.9e-86 289.9 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 KND99102.1 - 0.0085 15.6 2.8 0.45 9.9 0.0 2.9 2 1 1 3 3 3 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KND99102.1 - 0.2 10.9 0.0 0.5 9.6 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 BAR_3 PF16746.5 KND99106.1 - 3.7e-10 39.9 0.5 9.1e-10 38.6 0.5 1.7 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KND99106.1 - 6.2e-09 36.3 0.8 3.1e-08 34.1 0.0 2.5 3 0 0 3 3 3 1 PH domain VASt PF16016.5 KND99106.1 - 0.00054 20.4 0.0 0.0014 19.1 0.0 1.7 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain DUF896 PF05979.12 KND99106.1 - 0.033 14.1 0.5 0.57 10.1 0.0 3.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) E2R135 PF11570.8 KND99106.1 - 0.07 13.4 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 UMPH-1 PF05822.12 KND99108.1 - 0.18 11.3 0.0 1.7 8.1 0.0 1.9 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) RNase_PH PF01138.21 KND99110.1 - 2.9e-28 99.0 0.0 4.1e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 PEMT PF04191.13 KND99111.1 - 2.4e-59 198.3 13.5 1.3e-34 118.8 2.1 3.3 3 0 0 3 3 3 2 Phospholipid methyltransferase SKICH PF17751.1 KND99111.1 - 0.00022 21.7 0.4 0.00055 20.4 0.4 1.7 1 0 0 1 1 1 1 SKICH domain Cupin_8 PF13621.6 KND99111.1 - 0.06 13.0 0.1 0.092 12.4 0.1 1.2 1 0 0 1 1 1 0 Cupin-like domain MFS_1 PF07690.16 KND99113.1 - 3.1e-30 105.3 45.4 9.4e-23 80.7 25.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND99113.1 - 5.7e-19 68.3 19.0 1.4e-18 67.0 19.0 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 KND99113.1 - 0.00012 21.1 2.6 0.00012 21.1 2.6 1.7 1 1 0 1 1 1 1 MFS_1 like family zf-MIZ PF02891.20 KND99114.1 - 2.6e-10 39.9 0.9 9.7e-08 31.6 0.2 2.5 2 0 0 2 2 2 2 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KND99114.1 - 0.0037 17.0 0.5 0.012 15.4 0.1 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit SPATIAL PF15256.6 KND99114.1 - 0.0065 16.8 1.7 0.016 15.6 1.7 1.6 1 0 0 1 1 1 1 SPATIAL Ribosomal_L38e PF01781.18 KND99116.1 - 0.059 13.5 0.0 0.079 13.1 0.0 1.3 1 1 0 1 1 1 0 Ribosomal L38e protein family Aldedh PF00171.22 KND99117.1 - 1.9e-151 504.7 0.0 2.1e-151 504.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KND99117.1 - 0.18 11.2 0.1 2.3 7.6 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) DUF1308 PF07000.11 KND99118.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) zf-rbx1 PF12678.7 KND99119.1 - 2.6e-09 37.2 1.2 5.3e-09 36.2 1.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KND99119.1 - 9.6e-09 35.4 4.4 1.7e-08 34.6 1.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KND99119.1 - 2e-07 30.7 6.2 1.6e-06 27.8 2.0 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KND99119.1 - 8.1e-07 28.7 2.6 0.00021 20.9 0.2 2.9 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4 PF00097.25 KND99119.1 - 3.4e-06 26.8 2.2 6.9e-06 25.8 2.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KND99119.1 - 5.5e-06 26.2 1.0 1.2e-05 25.1 1.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KND99119.1 - 9.7e-05 22.3 1.1 0.00036 20.5 0.2 2.5 2 1 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KND99119.1 - 0.00015 21.6 1.8 0.00031 20.5 1.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KND99119.1 - 0.0022 18.0 0.5 0.005 16.9 0.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KND99119.1 - 0.0022 17.8 1.2 0.0022 17.8 1.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KND99119.1 - 0.01 15.4 1.7 0.036 13.7 1.7 1.9 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KND99119.1 - 0.66 10.2 4.8 3.2 8.0 4.8 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KND99119.1 - 0.86 9.5 3.7 1.4 8.8 0.4 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 KND99119.1 - 1.7 8.7 5.5 2.2 8.4 2.3 2.4 2 0 0 2 2 2 0 Zinc-finger Seryl_tRNA_N PF02403.22 KND99121.1 - 1.4 9.2 5.0 0.35 11.1 0.9 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Complex1_LYR_2 PF13233.6 KND99126.1 - 2.9e-18 66.4 0.1 3.9e-18 66.0 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KND99126.1 - 2.9e-08 33.6 0.1 7.8e-08 32.3 0.0 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) GLTP PF08718.11 KND99127.1 - 9e-47 159.1 0.1 1.5e-46 158.4 0.0 1.4 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) DUF1798 PF08807.10 KND99127.1 - 0.061 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) Corona_NS2 PF04753.12 KND99127.1 - 0.1 13.2 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 Coronavirus non-structural protein NS2 Med10 PF09748.9 KND99130.1 - 2.8e-33 114.4 0.0 3.4e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex L_protein_N PF15518.6 KND99130.1 - 0.041 13.7 0.0 11 5.9 0.0 2.3 2 0 0 2 2 2 0 L protein N-terminus Usp PF00582.26 KND99132.1 - 2e-05 25.2 0.0 4.6e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Universal stress protein family Cwf_Cwc_15 PF04889.12 KND99132.1 - 0.31 10.8 12.4 0.29 10.8 3.7 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Mid1 PF12929.7 KND99133.1 - 5.7e-132 440.9 5.3 7.6e-132 440.5 5.3 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KND99133.1 - 0.0038 17.8 6.3 0.17 12.5 6.3 2.6 1 1 0 1 1 1 1 Fz domain Rep_fac_C PF08542.11 KND99136.1 - 1.5e-15 57.4 0.4 1.2e-14 54.4 0.0 2.4 2 1 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KND99136.1 - 4.1e-11 42.9 0.1 4.1e-11 42.9 0.1 2.0 3 0 0 3 3 3 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 KND99136.1 - 8.2e-07 29.3 0.1 1.8e-06 28.1 0.1 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KND99136.1 - 2.2e-06 28.1 0.2 4.3e-06 27.2 0.2 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 KND99136.1 - 4.5e-06 26.6 0.9 7.1e-06 25.9 0.2 1.6 2 1 0 2 2 2 1 DNA polymerase III, delta subunit DEAD PF00270.29 KND99136.1 - 0.027 14.2 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Trns_repr_metal PF02583.17 KND99136.1 - 0.047 14.1 0.3 0.18 12.2 0.0 2.1 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor L27_1 PF09058.10 KND99136.1 - 0.068 13.2 1.5 0.14 12.1 0.1 2.3 3 0 0 3 3 3 0 L27_1 DDE_3 PF13358.6 KND99136.1 - 0.08 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease PH PF00169.29 KND99137.1 - 3.9e-27 94.8 10.4 4.7e-14 52.8 4.7 2.1 2 0 0 2 2 2 2 PH domain PH_3 PF14593.6 KND99137.1 - 2.1e-09 37.4 9.8 1.8e-06 28.0 1.9 2.5 2 1 0 2 2 2 2 PH domain PH_8 PF15409.6 KND99137.1 - 6.5e-07 29.5 9.2 3.2e-05 24.1 2.7 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 KND99137.1 - 9.3e-07 29.2 19.5 2.6e-05 24.6 8.8 3.8 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 KND99137.1 - 0.00023 21.5 15.0 0.058 13.8 6.7 3.9 2 2 0 2 2 2 2 Pleckstrin homology domain PH_13 PF16652.5 KND99137.1 - 0.00035 20.4 6.8 0.0086 15.9 2.5 2.4 2 1 0 2 2 2 2 Pleckstrin homology domain PH_2 PF08458.10 KND99137.1 - 0.0011 19.3 10.0 0.04 14.3 1.1 2.4 2 0 0 2 2 2 2 Plant pleckstrin homology-like region CagX PF03524.15 KND99137.1 - 0.0074 16.0 3.7 0.083 12.6 2.2 2.4 1 1 1 2 2 2 1 Conjugal transfer protein Mcp5_PH PF12814.7 KND99137.1 - 0.0092 16.1 13.1 0.36 11.0 0.2 2.5 2 1 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology PH_6 PF15406.6 KND99137.1 - 0.014 15.6 0.1 0.85 9.9 0.1 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain PEX-2N PF09263.10 KND99137.1 - 0.015 15.6 0.3 0.042 14.2 0.3 1.8 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal DUF4154 PF13689.6 KND99137.1 - 0.081 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 YfiR/HmsC-like Hydrolase_3 PF08282.12 KND99137.1 - 0.49 10.1 4.2 0.86 9.3 4.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase BCL_N PF04714.13 KND99137.1 - 2.7 8.1 8.2 0.28 11.3 1.1 2.9 3 0 0 3 3 3 0 BCL7, N-terminal conserver region CUE PF02845.16 KND99138.1 - 2.9e-08 33.3 0.3 0.0002 21.0 0.1 2.7 2 0 0 2 2 2 2 CUE domain Smr PF01713.21 KND99138.1 - 4.6e-06 26.9 0.0 2.9e-05 24.3 0.0 2.3 2 1 0 2 2 2 1 Smr domain DUF5393 PF17371.2 KND99138.1 - 0.041 12.0 0.0 0.061 11.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5393) Metal_resist PF13801.6 KND99138.1 - 0.17 12.1 1.0 0.38 10.9 0.1 1.9 2 0 0 2 2 2 0 Heavy-metal resistance Peptidase_M22 PF00814.25 KND99139.1 - 6.7e-85 285.1 0.0 8e-85 284.8 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KND99139.1 - 0.14 11.8 0.0 0.41 10.2 0.0 1.7 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus DASH_Spc34 PF08657.10 KND99140.1 - 4e-32 112.0 0.0 2.5e-29 102.9 0.0 2.1 1 1 0 1 1 1 1 DASH complex subunit Spc34 Prefoldin_2 PF01920.20 KND99140.1 - 0.0059 16.5 0.5 0.0059 16.5 0.5 2.2 2 0 0 2 2 2 1 Prefoldin subunit DUF948 PF06103.11 KND99140.1 - 0.19 12.0 0.9 2.5 8.4 0.0 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Ribosomal_L7Ae PF01248.26 KND99141.1 - 6.3e-22 77.1 0.0 6.9e-22 77.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L24e PF01246.20 KND99143.1 - 6.8e-30 103.1 0.1 6.8e-30 103.1 0.1 2.2 2 1 0 2 2 2 1 Ribosomal protein L24e Asparaginase_2 PF01112.18 KND99144.1 - 2.5e-15 56.3 0.0 5.4e-14 51.9 0.0 2.6 1 1 0 1 1 1 1 Asparaginase HCO3_cotransp PF00955.21 KND99145.1 - 1.6e-78 264.8 13.2 1.4e-43 149.5 7.2 2.0 1 1 1 2 2 2 2 HCO3- transporter family La PF05383.17 KND99147.1 - 1.1e-16 60.6 0.0 2.4e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 La domain Tim17 PF02466.19 KND99149.1 - 3.3e-06 27.4 0.2 6.8e-06 26.4 0.1 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family ABC2_membrane PF01061.24 KND99149.1 - 0.011 15.2 0.6 0.089 12.2 0.0 2.0 2 0 0 2 2 2 0 ABC-2 type transporter DCA16 PF15349.6 KND99149.1 - 0.054 13.0 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 Thioredoxin PF00085.20 KND99150.1 - 4.1e-53 177.7 0.5 2.2e-26 91.9 0.0 3.9 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 KND99150.1 - 6.8e-22 78.3 3.3 9.2e-17 61.5 0.3 2.7 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KND99150.1 - 1.3e-09 38.5 0.8 0.0015 18.9 0.0 3.2 3 1 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KND99150.1 - 1.5e-07 31.0 0.0 0.023 14.0 0.0 2.7 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KND99150.1 - 9.9e-07 28.9 0.0 0.052 13.7 0.0 3.0 3 0 0 3 3 2 2 Thioredoxin-like Calsequestrin PF01216.17 KND99150.1 - 1.9e-05 23.9 0.6 1.9e-05 23.9 0.6 1.9 1 1 1 2 2 2 1 Calsequestrin Thioredoxin_8 PF13905.6 KND99150.1 - 6.9e-05 23.1 0.2 0.71 10.2 0.0 3.7 4 0 0 4 4 4 2 Thioredoxin-like Redoxin PF08534.10 KND99150.1 - 0.00063 19.5 0.2 0.28 10.9 0.0 3.5 3 1 1 4 4 4 1 Redoxin AhpC-TSA PF00578.21 KND99150.1 - 0.0023 17.8 0.6 0.83 9.6 0.0 3.4 3 1 0 3 3 3 1 AhpC/TSA family Thioredoxin_9 PF14595.6 KND99150.1 - 0.017 14.9 0.1 3.9 7.3 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin TraF PF13728.6 KND99150.1 - 0.048 13.5 0.0 0.54 10.0 0.0 2.2 2 0 0 2 2 2 0 F plasmid transfer operon protein EBV-NA1 PF02905.14 KND99150.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain WD40 PF00400.32 KND99151.1 - 1e-12 48.3 13.3 0.00097 19.9 0.3 6.7 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND99151.1 - 3.1e-07 30.6 0.0 0.31 11.3 0.0 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KND99151.1 - 0.031 13.3 0.2 5.8 5.8 0.0 2.7 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein dCache_1 PF02743.18 KND99151.1 - 0.088 12.6 1.3 0.61 9.8 0.3 2.4 2 0 0 2 2 2 0 Cache domain Fungal_trans PF04082.18 KND99155.1 - 7.7e-08 31.7 0.2 1.8e-07 30.5 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_1 PF00561.20 KND99157.1 - 4e-50 170.8 0.0 4.9e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KND99157.1 - 0.00055 20.6 0.0 0.00084 20.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Glyco_transf_28 PF03033.20 KND99158.1 - 8.5e-32 110.1 0.3 5.1e-31 107.6 0.0 2.5 4 0 0 4 4 4 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 KND99158.1 - 1.2e-27 96.1 0.2 6.1e-22 77.7 0.1 2.7 2 0 0 2 2 2 2 GRAM domain UDPGT PF00201.18 KND99158.1 - 2.4e-10 39.8 0.0 4.7e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.29 KND99158.1 - 0.0013 19.2 0.0 0.094 13.2 0.0 3.6 2 1 0 2 2 2 1 PH domain Glyco_tran_28_C PF04101.16 KND99158.1 - 0.13 12.3 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain ABC_membrane PF00664.23 KND99159.1 - 3.3e-55 187.7 1.1 4.1e-55 187.4 1.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KND99159.1 - 1.1e-33 116.6 0.0 2.3e-33 115.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KND99159.1 - 1.2e-06 28.1 0.0 0.00034 20.1 0.0 2.5 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KND99159.1 - 1.8e-05 25.0 0.3 0.00022 21.5 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KND99159.1 - 0.00011 22.7 0.5 0.0017 18.8 0.5 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KND99159.1 - 0.00028 20.7 0.3 0.01 15.6 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 KND99159.1 - 0.00063 20.2 0.0 0.0014 19.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KND99159.1 - 0.00095 18.9 0.0 0.0027 17.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 KND99159.1 - 0.0011 19.0 0.0 0.014 15.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KND99159.1 - 0.0023 17.4 0.0 0.0043 16.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 KND99159.1 - 0.0041 17.3 0.0 0.019 15.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KND99159.1 - 0.0058 16.4 0.1 0.28 10.9 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 KND99159.1 - 0.0066 16.4 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 KND99159.1 - 0.0085 16.6 0.0 0.026 15.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.6 KND99159.1 - 0.0087 15.6 0.0 3.9 7.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 KND99159.1 - 0.036 14.1 0.0 0.69 10.0 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_21 PF13304.6 KND99159.1 - 0.058 13.2 0.5 0.26 11.1 0.1 2.2 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KND99159.1 - 0.068 13.7 0.5 0.15 12.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain TniB PF05621.11 KND99159.1 - 0.068 12.6 0.0 4.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein SbcCD_C PF13558.6 KND99159.1 - 0.091 13.0 1.4 0.95 9.7 1.4 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DEAD PF00270.29 KND99159.1 - 0.1 12.4 0.0 6.2 6.6 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_30 PF13604.6 KND99159.1 - 0.12 12.1 0.0 6.6 6.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KND99159.1 - 0.15 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase LRR_8 PF13855.6 KND99160.1 - 0.0016 18.2 19.1 0.15 11.9 3.0 4.7 2 2 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 KND99160.1 - 0.0098 16.3 18.1 0.038 14.4 3.0 4.4 2 2 2 4 4 4 2 Leucine Rich repeats (2 copies) F-box PF00646.33 KND99160.1 - 0.021 14.7 0.9 0.052 13.4 0.9 1.8 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KND99160.1 - 0.099 12.6 1.1 0.22 11.5 1.1 1.6 1 0 0 1 1 1 0 F-box-like LRR_1 PF00560.33 KND99160.1 - 0.36 11.5 15.4 4.5 8.2 0.0 5.8 5 0 0 5 5 5 0 Leucine Rich Repeat SYF2 PF08231.12 KND99161.1 - 3.5e-09 37.3 26.3 2.8e-08 34.3 17.6 3.0 1 1 1 2 2 2 1 SYF2 splicing factor Methyltransf_24 PF13578.6 KND99162.1 - 2.9e-10 41.1 0.0 4.6e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KND99162.1 - 4.4e-10 39.1 0.1 9.9e-10 37.9 0.1 1.5 1 1 0 1 1 1 1 O-methyltransferase Syntaxin-18_N PF10496.9 KND99163.1 - 8.7e-10 38.7 0.1 8.7e-10 38.7 0.1 2.6 2 2 2 4 4 4 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 KND99163.1 - 0.013 15.5 0.2 0.026 14.5 0.2 1.6 1 0 0 1 1 1 0 SNARE domain DUF349 PF03993.12 KND99163.1 - 1.2 9.5 9.4 0.14 12.4 2.4 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) HSF_DNA-bind PF00447.17 KND99163.1 - 3.2 8.4 8.2 0.3 11.7 1.7 2.3 1 1 1 2 2 2 0 HSF-type DNA-binding DUF2115 PF09888.9 KND99163.1 - 4.5 7.8 7.5 18 5.8 0.8 3.0 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) GTP_EFTU PF00009.27 KND99164.1 - 6.6e-47 159.6 0.1 1.1e-46 158.8 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KND99164.1 - 2.7e-09 37.3 0.3 1.4e-08 35.0 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KND99164.1 - 1e-06 28.8 0.3 7.2e-05 22.8 0.1 3.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 KND99164.1 - 0.0072 15.8 0.0 0.54 9.7 0.0 2.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KND99164.1 - 0.057 13.7 0.1 0.19 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain HBS1_N PF08938.10 KND99165.1 - 2e-15 56.8 2.2 2.5e-15 56.5 2.2 1.0 1 0 0 1 1 1 1 HBS1 N-terminus V-ATPase_H_N PF03224.14 KND99166.1 - 6e-39 134.2 8.1 6e-39 134.2 8.1 1.7 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KND99166.1 - 2.4e-28 98.6 3.6 1e-27 96.6 0.1 2.8 2 1 0 2 2 2 1 V-ATPase subunit H BIR PF00653.21 KND99168.1 - 1.8e-31 108.6 3.9 4.4e-19 68.9 0.9 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-BED PF02892.15 KND99168.1 - 0.44 10.6 1.8 0.66 10.0 0.1 2.1 2 0 0 2 2 2 0 BED zinc finger PyrI_C PF02748.15 KND99168.1 - 0.71 9.8 2.3 17 5.4 0.1 2.6 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain SAPS PF04499.15 KND99170.1 - 3.4e-146 487.9 0.8 3.4e-146 487.9 0.8 2.3 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein PAD PF03068.15 KND99170.1 - 0.0073 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) Post_transc_reg PF13797.6 KND99170.1 - 0.081 12.8 0.1 0.27 11.1 0.1 1.9 1 0 0 1 1 1 0 Post-transcriptional regulator DnaJ PF00226.31 KND99171.1 - 1.9e-14 53.5 0.1 3.6e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain OAD_gamma PF04277.13 KND99171.1 - 1.8 9.2 0.0 1.8 9.2 0.0 2.6 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain PTPLA PF04387.14 KND99172.1 - 8.7e-10 38.6 7.3 8.7e-10 38.6 7.3 1.8 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA ACT PF01842.25 KND99173.1 - 0.015 15.1 0.4 0.041 13.7 0.1 1.8 2 0 0 2 2 2 0 ACT domain RXT2_N PF08595.11 KND99173.1 - 0.088 12.8 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal MRP_L53 PF10780.9 KND99175.1 - 8.5e-15 54.7 0.0 1.2e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 NMO PF03060.15 KND99176.1 - 1.2e-41 143.2 0.4 1.8e-41 142.6 0.4 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KND99176.1 - 2.6e-07 30.0 0.1 1.9e-06 27.1 0.1 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KND99176.1 - 2.9e-05 23.3 1.9 0.00091 18.4 0.2 2.2 2 0 0 2 2 2 2 FMN-dependent dehydrogenase DHO_dh PF01180.21 KND99176.1 - 0.0034 16.6 0.1 0.037 13.3 0.0 2.2 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase FAD_binding_6 PF00970.24 KND99177.1 - 1.6e-11 44.5 0.0 3.6e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KND99177.1 - 2.1e-08 34.8 0.0 6.5e-07 30.0 0.0 2.7 2 2 0 2 2 2 1 Oxidoreductase NAD-binding domain Globin PF00042.22 KND99177.1 - 2.4e-06 28.1 0.5 6.3e-06 26.7 0.0 2.0 2 1 0 2 2 2 1 Globin NAD_binding_6 PF08030.12 KND99177.1 - 0.0023 18.1 0.0 0.0044 17.2 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain D-ser_dehydrat PF14031.6 KND99178.1 - 4.5e-22 78.5 0.0 1e-21 77.4 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KND99178.1 - 1.8e-12 47.4 0.1 2.5e-12 46.9 0.1 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Fer2_3 PF13085.6 KND99180.1 - 6.8e-33 112.9 0.1 1.1e-32 112.3 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KND99180.1 - 1.7e-09 38.1 8.0 1.7e-09 38.1 8.0 2.1 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KND99180.1 - 3.2e-08 33.9 7.7 3.2e-08 33.9 7.7 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KND99180.1 - 1.5e-07 31.4 3.7 1.5e-07 31.4 3.7 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KND99180.1 - 0.00073 20.1 5.4 0.00073 20.1 5.4 2.6 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 KND99180.1 - 0.0028 17.6 5.7 0.0041 17.0 1.7 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 KND99180.1 - 0.087 13.0 12.4 0.045 13.9 7.6 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain 2-Hacid_dh_C PF02826.19 KND99182.1 - 8.7e-40 136.0 0.0 3.2e-39 134.1 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KND99182.1 - 2e-17 63.1 0.0 2.7e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Zn_clus PF00172.18 KND99183.1 - 5e-05 23.3 8.8 0.0001 22.3 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND99183.1 - 0.0022 17.1 1.4 0.01 14.9 1.2 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sec62 PF03839.16 KND99183.1 - 0.03 13.8 0.3 0.051 13.1 0.3 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 MFS_1 PF07690.16 KND99185.1 - 3.2e-25 88.8 32.6 3.9e-25 88.5 32.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily NDT80_PhoG PF05224.12 KND99186.1 - 4.2e-17 63.0 0.6 4.2e-17 63.0 0.6 2.4 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Aminotran_1_2 PF00155.21 KND99187.1 - 8.1e-44 150.3 0.0 9.5e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KND99187.1 - 6.4e-08 31.5 0.0 9e-08 31.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KND99187.1 - 4.1e-07 29.3 0.0 1.1e-06 27.9 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KND99187.1 - 1.4e-05 24.6 0.0 2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Alliinase_C PF04864.13 KND99187.1 - 0.025 13.5 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Allinase Chordopox_A35R PF05989.12 KND99187.1 - 0.086 12.7 0.2 0.66 9.8 0.0 2.2 2 0 0 2 2 2 0 Chordopoxvirus A35R protein Aminotran_3 PF00202.21 KND99187.1 - 0.15 10.6 0.0 0.27 9.9 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III Pkinase PF00069.25 KND99189.1 - 6.8e-62 209.2 0.1 1.4e-61 208.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND99189.1 - 5.5e-29 101.2 0.0 1e-28 100.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KND99189.1 - 0.0087 15.0 0.3 0.059 12.3 0.0 2.3 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KND99189.1 - 0.13 12.2 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family VASP_tetra PF08776.11 KND99189.1 - 0.15 11.6 0.4 0.34 10.5 0.4 1.6 1 0 0 1 1 1 0 VASP tetramerisation domain WD40 PF00400.32 KND99190.1 - 1.3e-06 29.1 0.9 0.088 13.7 0.2 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat EPL1 PF10513.9 KND99191.1 - 2.5e-27 96.2 9.7 2.5e-27 96.2 9.7 3.8 3 0 0 3 3 3 1 Enhancer of polycomb-like NAD_binding_10 PF13460.6 KND99192.1 - 1.5e-37 129.3 2.3 1.8e-37 129.0 2.3 1.0 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KND99192.1 - 5.6e-09 35.8 0.3 1.5e-08 34.4 0.2 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KND99192.1 - 8.2e-07 28.8 4.1 3e-06 27.0 4.1 1.7 1 1 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KND99192.1 - 5.7e-05 23.4 1.0 8.3e-05 22.9 1.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KND99192.1 - 0.00021 20.4 0.8 0.00029 19.9 0.8 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KND99192.1 - 0.00038 20.9 0.2 0.00077 19.9 0.2 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KND99192.1 - 0.0013 18.9 1.0 0.0028 17.8 1.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 KND99192.1 - 0.0023 17.4 2.5 0.0031 17.0 2.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KND99192.1 - 0.0047 16.1 0.1 0.0086 15.2 0.1 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 KND99192.1 - 0.014 15.4 1.1 0.021 14.7 0.9 1.5 1 1 0 1 1 1 0 KR domain ApbA PF02558.16 KND99192.1 - 0.073 12.7 0.2 0.12 12.0 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ldh_1_N PF00056.23 KND99192.1 - 0.12 12.5 2.6 0.21 11.7 2.6 1.5 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain FTHFS PF01268.19 KND99193.1 - 3.4e-242 804.6 2.1 4.2e-242 804.3 2.1 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KND99193.1 - 4.6e-67 224.3 1.3 2e-66 222.2 0.6 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KND99193.1 - 2.6e-34 117.9 0.3 1e-33 116.0 0.3 2.1 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 KND99193.1 - 0.053 12.4 0.1 0.11 11.4 0.1 1.5 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family SUB1_ProdP9 PF18213.1 KND99193.1 - 0.11 12.3 0.3 0.7 9.8 0.0 2.3 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 FH2 PF02181.23 KND99194.1 - 2e-68 231.2 12.7 2e-68 231.2 12.7 2.5 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KND99194.1 - 4.3e-15 55.8 7.7 4.3e-15 55.8 7.7 4.6 3 1 0 3 3 3 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KND99194.1 - 2e-12 47.2 4.4 2e-12 47.2 4.4 3.7 4 1 0 4 4 4 1 Diaphanous FH3 Domain SlyX PF04102.12 KND99194.1 - 0.057 14.0 0.3 0.057 14.0 0.3 4.4 4 0 0 4 4 4 0 SlyX DUF1192 PF06698.11 KND99194.1 - 0.088 12.9 4.3 1.7 8.8 0.5 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) TSC22 PF01166.18 KND99194.1 - 0.22 11.9 2.6 11 6.4 0.0 3.4 1 1 0 2 2 2 0 TSC-22/dip/bun family TMEM108 PF15759.5 KND99196.1 - 2.5 7.0 3.8 2.7 6.9 3.8 1.0 1 0 0 1 1 1 0 TMEM108 family PIF1 PF05970.14 KND99197.1 - 2.3e-51 175.1 0.5 6.4e-40 137.4 0.1 2.4 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KND99197.1 - 2e-22 79.9 0.0 3.2e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KND99197.1 - 3.2e-09 37.3 0.0 7.3e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 KND99197.1 - 2.2e-06 25.9 0.0 2.4e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Helicase DUF2075 PF09848.9 KND99197.1 - 6.5e-06 25.6 0.0 1.3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KND99197.1 - 2.4e-05 24.6 0.0 7.8e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain SH3_13 PF18335.1 KND99197.1 - 0.00085 19.1 1.5 0.0019 18.0 0.0 2.4 3 0 0 3 3 3 1 ATP-dependent RecD-like DNA helicase SH3 domain Viral_helicase1 PF01443.18 KND99197.1 - 0.0014 18.5 0.3 2.2 8.0 0.0 3.0 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA PF00004.29 KND99197.1 - 0.0014 19.0 0.4 0.0035 17.8 0.1 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 KND99197.1 - 0.0021 17.8 0.1 0.0061 16.4 0.1 1.8 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_7 PF12775.7 KND99197.1 - 0.0039 16.7 0.0 0.0074 15.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 KND99197.1 - 0.0049 16.0 0.0 0.008 15.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 KND99197.1 - 0.0066 16.8 0.0 0.018 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.16 KND99197.1 - 0.0066 15.9 0.0 0.019 14.5 0.0 1.7 1 0 0 1 1 1 1 PhoH-like protein AAA_11 PF13086.6 KND99197.1 - 0.025 14.4 0.0 0.025 14.4 0.0 2.5 3 1 1 4 4 4 0 AAA domain UvrD-helicase PF00580.21 KND99197.1 - 0.029 13.9 0.0 0.029 13.9 0.0 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF87 PF01935.17 KND99197.1 - 0.03 14.4 2.4 0.065 13.3 0.0 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_24 PF13479.6 KND99197.1 - 0.051 13.3 0.5 1.1 9.0 0.1 2.5 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KND99197.1 - 0.062 13.0 0.2 1 9.1 0.0 2.3 1 1 1 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KND99197.1 - 0.073 13.5 0.1 0.21 12.0 0.1 1.8 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 KND99197.1 - 0.083 13.4 0.1 0.31 11.5 0.1 2.1 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 KND99197.1 - 0.09 12.5 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.15 KND99197.1 - 0.12 12.3 0.7 9.1 6.2 0.2 2.5 2 0 0 2 2 2 0 NTPase Helicase_RecD PF05127.14 KND99197.1 - 0.15 11.9 0.2 0.66 9.8 0.2 2.1 1 1 0 1 1 1 0 Helicase ResIII PF04851.15 KND99197.1 - 0.31 11.0 2.1 0.34 10.9 0.0 2.1 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit DUF2625 PF10946.8 KND99199.1 - 0.14 11.2 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF2625 Fungal_trans PF04082.18 KND99200.1 - 1.4e-27 96.5 1.8 2.4e-27 95.6 1.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-RING_2 PF13639.6 KND99201.1 - 4.2e-07 30.2 9.0 1.1e-06 28.9 9.0 1.8 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KND99201.1 - 9e-06 25.8 6.1 2.8e-05 24.2 6.1 1.8 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KND99201.1 - 0.00058 19.9 2.9 0.0013 18.8 2.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KND99201.1 - 0.0015 18.7 7.5 0.0037 17.5 7.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain RINGv PF12906.7 KND99201.1 - 0.011 15.8 7.7 0.024 14.8 7.7 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4 PF00097.25 KND99201.1 - 0.027 14.3 9.9 0.07 13.0 9.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KND99201.1 - 0.047 14.0 7.9 0.097 13.0 7.9 1.6 1 0 0 1 1 1 0 RING-like domain DUF4609 PF15382.6 KND99201.1 - 0.055 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4609) Zn_ribbon_17 PF17120.5 KND99201.1 - 0.093 12.4 6.4 0.24 11.0 6.4 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KND99201.1 - 0.5 10.2 9.1 1.2 9.0 9.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 KND99201.1 - 2 8.4 7.3 0.96 9.4 4.9 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 KND99201.1 - 7.9 6.5 7.5 15 5.5 7.5 1.5 1 0 0 1 1 1 0 PHD-finger PTPA PF03095.15 KND99202.1 - 8.6e-95 317.7 0.0 1e-94 317.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein XPG_I PF00867.18 KND99203.1 - 1.5e-25 89.4 0.1 1.3e-24 86.4 0.0 2.4 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.7 KND99203.1 - 8.4e-06 25.4 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing XPG_N PF00752.17 KND99203.1 - 0.0072 16.8 0.0 0.02 15.3 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain Glyco_hydro_3 PF00933.21 KND99204.1 - 5.8e-55 186.9 0.0 8.8e-55 186.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PEPCK_ATP PF01293.20 KND99205.1 - 1.2e-218 726.4 0.0 1.4e-218 726.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase ATPase PF06745.13 KND99205.1 - 0.082 12.2 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.6 KND99205.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain p450 PF00067.22 KND99207.1 - 1.1e-62 212.3 0.0 1.4e-62 212.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Nup192 PF11894.8 KND99208.1 - 0 1377.8 56.1 0 1377.6 56.1 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 AA_permease PF00324.21 KND99211.1 - 9.1e-108 360.9 35.7 1.1e-107 360.6 35.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND99211.1 - 1.6e-23 83.3 35.7 2.2e-23 82.8 35.7 1.2 1 0 0 1 1 1 1 Amino acid permease PIN_4 PF13638.6 KND99212.1 - 8.7e-18 64.9 0.3 2.2e-17 63.6 0.3 1.7 1 0 0 1 1 1 1 PIN domain PIN_12 PF16289.5 KND99212.1 - 0.087 13.3 0.3 0.087 13.3 0.3 2.6 3 0 0 3 3 3 0 PIN domain TPR_MLP1_2 PF07926.12 KND99213.1 - 1.1e-06 28.7 20.1 1.1e-06 28.7 20.1 18.2 7 5 10 19 19 19 6 TPR/MLP1/MLP2-like protein DUF4231 PF14015.6 KND99213.1 - 0.084 13.3 3.1 22 5.6 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF2015 PF09435.10 KND99213.1 - 1 9.2 6.5 0.46 10.4 2.4 2.7 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2015) MFS_1 PF07690.16 KND99214.1 - 8e-38 130.3 29.4 8e-38 130.3 29.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND99214.1 - 1.1e-08 34.4 34.8 2.1e-06 26.9 14.4 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 KND99214.1 - 4.6e-05 22.5 7.6 4.6e-05 22.5 7.6 3.1 2 2 0 2 2 2 1 MFS_1 like family DAGK_cat PF00781.24 KND99215.1 - 5.7e-13 48.6 0.0 1.6e-12 47.2 0.0 1.7 1 1 1 2 2 2 1 Diacylglycerol kinase catalytic domain XRN_M PF17846.1 KND99216.1 - 5.6e-134 447.4 1.9 1.5e-133 446.0 1.9 1.7 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KND99216.1 - 1.2e-96 322.8 0.0 3.2e-96 321.4 0.0 1.8 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Sugar_tr PF00083.24 KND99217.1 - 1.8e-82 277.6 24.8 2.2e-82 277.4 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND99217.1 - 1.5e-18 66.9 24.9 1.1e-16 60.7 21.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily ATG11 PF10377.9 KND99217.1 - 0.049 13.7 0.0 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 Autophagy-related protein 11 Motilin_ghrelin PF04644.12 KND99218.1 - 0.088 12.6 2.8 0.14 12.0 2.8 1.3 1 0 0 1 1 1 0 Motilin/ghrelin PLU-1 PF08429.11 KND99220.1 - 1.4e-49 169.1 5.5 5.7e-49 167.1 2.0 2.6 2 1 0 2 2 2 1 PLU-1-like protein JmjC PF02373.22 KND99220.1 - 7.2e-21 74.7 0.4 3.6e-10 40.3 0.4 2.9 2 0 0 2 2 2 2 JmjC domain, hydroxylase ARID PF01388.21 KND99220.1 - 3.8e-14 53.1 0.0 1.6e-13 51.1 0.0 2.2 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 KND99220.1 - 6.2e-09 35.6 9.8 1.2e-08 34.7 9.8 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KND99220.1 - 0.0068 16.6 1.9 0.021 15.0 1.9 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KND99220.1 - 0.019 15.1 2.1 0.049 13.8 2.1 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain STI1 PF17830.1 KND99220.1 - 0.062 13.2 0.0 0.31 11.0 0.0 2.2 1 0 0 1 1 1 0 STI1 domain PHD_4 PF16866.5 KND99220.1 - 2.4 8.3 7.3 7.9 6.7 7.3 1.9 1 0 0 1 1 1 0 PHD-finger MPS2 PF17060.5 KND99221.1 - 0.0014 18.0 7.2 0.0072 15.6 0.8 2.4 1 1 2 3 3 3 3 Monopolar spindle protein 2 SlyX PF04102.12 KND99221.1 - 0.12 13.1 3.4 0.24 12.0 0.5 2.5 1 1 1 2 2 2 0 SlyX AA_permease_2 PF13520.6 KND99222.1 - 1.2e-60 205.6 46.7 1.4e-60 205.3 46.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KND99222.1 - 5.5e-14 51.6 40.9 1.1e-13 50.6 40.9 1.5 1 1 0 1 1 1 1 Amino acid permease Peptidase_S10 PF00450.22 KND99223.1 - 1.2e-123 413.6 0.0 1.6e-123 413.3 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DPRP PF04244.13 KND99224.1 - 0.024 14.5 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein RTP1_C1 PF10363.9 KND99224.1 - 0.027 14.7 0.5 0.086 13.0 0.5 1.9 1 1 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 NTR PF01759.21 KND99224.1 - 0.2 11.5 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 UNC-6/NTR/C345C module COX14 PF14880.6 KND99225.1 - 1.1e-11 44.4 0.1 1.5e-11 44.0 0.1 1.3 1 1 0 1 1 1 1 Cytochrome oxidase c assembly BRX PF08381.11 KND99225.1 - 0.15 11.4 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 Prefoldin PF02996.17 KND99226.1 - 2e-23 82.6 3.0 2e-23 82.6 3.0 1.3 1 1 0 1 1 1 1 Prefoldin subunit RSS_P20 PF11757.8 KND99226.1 - 0.056 13.9 2.1 4.1 7.9 0.1 2.1 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain LEM PF03020.15 KND99226.1 - 0.14 11.7 0.1 0.14 11.7 0.1 1.8 2 0 0 2 2 2 0 LEM domain CdvA PF18822.1 KND99226.1 - 0.26 11.1 7.4 0.32 10.8 1.8 2.3 2 0 0 2 2 2 0 CdvA-like coiled-coil domain SYCE1 PF15233.6 KND99226.1 - 0.37 10.8 14.8 0.068 13.2 5.8 2.1 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 Rad10 PF03834.14 KND99227.1 - 1.2e-37 128.4 0.3 2.4e-37 127.4 0.1 1.6 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) UTP25 PF06862.12 KND99228.1 - 7.1e-194 645.0 8.5 8.6e-194 644.7 8.5 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 KND99228.1 - 0.0018 18.1 0.0 0.27 11.0 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase DUF5347 PF17282.2 KND99228.1 - 0.088 13.1 0.3 6.8 7.1 0.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5347) ICE2 PF08426.10 KND99229.1 - 2.5e-139 464.9 22.1 3.2e-139 464.5 22.1 1.1 1 0 0 1 1 1 1 ICE2 DUF1776 PF08643.10 KND99231.1 - 9e-83 278.0 0.0 1.5e-82 277.3 0.0 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short_C2 PF13561.6 KND99231.1 - 0.012 15.2 0.0 0.032 13.8 0.0 1.6 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND99231.1 - 0.17 11.3 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase OPT PF03169.15 KND99232.1 - 3.2e-131 439.0 44.0 3.7e-131 438.8 44.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PetM PF08041.11 KND99232.1 - 0.83 9.3 4.3 3.5 7.3 4.3 2.2 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 Gln-synt_C PF00120.24 KND99234.1 - 3.1e-21 75.7 0.0 2.2e-20 72.9 0.0 1.9 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KND99234.1 - 4.1e-14 52.1 0.0 6.7e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain ERAP1_C PF11838.8 KND99238.1 - 0.026 14.1 0.0 0.026 14.1 0.0 1.0 1 0 0 1 1 1 0 ERAP1-like C-terminal domain OPT PF03169.15 KND99239.1 - 3.8e-161 537.8 46.0 4.4e-161 537.6 46.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pox_C4_C10 PF03336.13 KND99239.1 - 0.066 12.3 0.1 0.1 11.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus C4/C10 protein DUF1687 PF07955.11 KND99241.1 - 3.5e-31 108.3 0.2 4.4e-31 108.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) DSPc PF00782.20 KND99243.1 - 5.4e-28 97.4 0.0 1.4e-27 96.1 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KND99243.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ank_2 PF12796.7 KND99244.1 - 6.7e-36 122.7 4.6 3.3e-19 69.2 0.3 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND99244.1 - 4.1e-26 91.0 0.2 6.3e-10 39.4 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KND99244.1 - 1e-24 86.3 4.3 2.9e-07 30.6 0.0 5.4 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND99244.1 - 1e-23 80.8 0.5 8.2e-07 28.9 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 KND99244.1 - 1.1e-21 76.3 3.2 7.7e-06 26.1 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat DUF2011 PF09428.10 KND99245.1 - 1.7e-10 41.0 0.1 4.3e-10 39.7 0.1 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) COG5 PF10392.9 KND99246.1 - 3.5e-37 127.5 1.3 3.5e-37 127.5 1.3 1.7 2 0 0 2 2 2 1 Golgi transport complex subunit 5 DUF4864 PF16156.5 KND99246.1 - 0.011 16.4 1.0 4 8.2 0.1 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4864) Sec23_trunk PF04811.15 KND99247.1 - 1.2e-62 211.7 0.0 2e-62 210.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KND99247.1 - 3.2e-19 68.6 0.0 9.4e-19 67.1 0.0 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KND99247.1 - 4.3e-18 65.9 0.0 9.4e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KND99247.1 - 3e-16 59.2 4.9 5.6e-16 58.3 4.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 KND99247.1 - 0.066 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Gelsolin PF00626.22 KND99247.1 - 0.19 11.7 2.0 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 Gelsolin repeat Peptidase_M48 PF01435.18 KND99249.1 - 5.6e-38 130.7 0.0 9.6e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M48_N PF16491.5 KND99249.1 - 2.6e-31 108.9 12.6 2.6e-31 108.9 12.6 1.7 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices GtrA PF04138.14 KND99249.1 - 0.0015 18.7 11.3 0.0015 18.7 11.3 2.0 2 0 0 2 2 2 1 GtrA-like protein MgtE PF01769.16 KND99249.1 - 7.3 7.0 9.9 0.35 11.3 2.7 2.4 2 1 1 3 3 3 0 Divalent cation transporter Peptidase_S8 PF00082.22 KND99250.1 - 7.9e-27 94.3 5.2 1.6e-26 93.2 5.2 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KND99250.1 - 1.4e-08 35.2 0.0 2.8e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.22 KND99251.1 - 8.8e-29 100.7 8.4 1.9e-28 99.6 8.4 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KND99251.1 - 1.1e-10 42.0 0.1 2e-10 41.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 G6PD_C PF02781.16 KND99253.1 - 1.5e-108 362.4 0.0 2e-108 362.0 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KND99253.1 - 5.3e-60 203.1 0.1 1.1e-59 202.1 0.1 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Peptidase_S8 PF00082.22 KND99254.1 - 2.7e-38 131.9 3.5 2.7e-38 131.9 3.5 1.9 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.20 KND99254.1 - 3.2e-24 84.7 0.5 1e-23 83.2 0.5 1.9 1 0 0 1 1 1 1 Proprotein convertase P-domain Macoilin PF09726.9 KND99254.1 - 0.14 10.7 6.7 0.22 10.0 6.7 1.2 1 0 0 1 1 1 0 Macoilin family BUD22 PF09073.10 KND99254.1 - 0.25 10.6 24.7 0.49 9.7 24.7 1.4 1 0 0 1 1 1 0 BUD22 Med13_C PF06333.12 KND99254.1 - 0.31 10.2 6.8 0.56 9.4 6.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Mucin PF01456.17 KND99254.1 - 0.39 10.7 20.8 0.99 9.4 20.8 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF4820 PF16091.5 KND99254.1 - 6.8 6.0 12.9 16 4.7 12.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Fe_hyd_lg_C PF02906.14 KND99256.1 - 1.3e-61 208.4 0.0 2.3e-61 207.6 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Ytp1 PF10355.9 KND99258.1 - 1.3e-63 214.8 15.9 2.6e-62 210.5 15.9 2.1 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) Thioredoxin PF00085.20 KND99259.1 - 2.7e-10 40.2 0.0 5.2e-10 39.2 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KND99259.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.6 KND99259.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin AhpC-TSA PF00578.21 KND99259.1 - 0.11 12.4 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 AhpC/TSA family OPT PF03169.15 KND99263.1 - 6.9e-160 533.7 41.6 7.9e-160 533.5 41.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4064 PF13273.6 KND99263.1 - 0.091 13.0 0.3 0.091 13.0 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Phage_holin_2_3 PF16080.5 KND99263.1 - 0.32 10.8 2.6 22 4.9 0.3 2.8 2 0 0 2 2 2 0 Bacteriophage holin family HP1 OPT PF03169.15 KND99264.1 - 3.4e-166 554.5 43.2 3.9e-166 554.3 43.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TMEM192 PF14802.6 KND99264.1 - 7.2 5.6 7.8 0.48 9.5 1.0 2.3 3 0 0 3 3 3 0 TMEM192 family PTPLA PF04387.14 KND99265.1 - 9.7e-42 142.5 11.8 1.8e-41 141.6 11.8 1.5 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA PTPLA PF04387.14 KND99266.1 - 1.5e-52 177.7 9.6 2.1e-52 177.2 9.6 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA ChAPs PF09295.10 KND99267.1 - 1.5e-24 86.8 0.1 5e-17 62.0 0.0 2.4 2 1 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 KND99267.1 - 4.7e-05 23.8 0.0 8.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KND99267.1 - 0.009 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat LRR_8 PF13855.6 KND99268.1 - 1.3e-48 162.5 69.4 3e-09 36.5 9.8 10.1 5 3 6 11 11 11 9 Leucine rich repeat PP2C PF00481.21 KND99268.1 - 1.7e-35 122.9 0.0 3.5e-35 121.9 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 KND99268.1 - 3.7e-30 103.4 87.5 6.2e-07 29.6 1.7 13.6 3 3 10 15 15 15 13 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 KND99268.1 - 2.5e-29 102.2 0.0 6.3e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 KND99268.1 - 0.00019 21.0 31.0 0.0019 17.8 1.5 5.4 3 1 2 5 5 5 2 Leucine-rich repeat LRR_1 PF00560.33 KND99268.1 - 0.0085 16.5 58.6 9.4 7.2 0.0 15.4 15 1 0 15 15 15 2 Leucine Rich Repeat LRR_5 PF13306.6 KND99268.1 - 0.0096 15.9 11.5 0.43 10.6 0.6 3.9 3 1 1 4 4 4 2 BspA type Leucine rich repeat region (6 copies) AA_permease PF00324.21 KND99269.1 - 1.2e-64 218.7 42.8 1.4e-64 218.5 42.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND99269.1 - 3.3e-15 55.9 47.3 4.1e-15 55.5 47.3 1.1 1 0 0 1 1 1 1 Amino acid permease OPT PF03169.15 KND99270.1 - 1.5e-170 568.9 41.0 1.7e-170 568.7 41.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.15 KND99272.1 - 5.8e-160 533.9 45.7 6.7e-160 533.7 45.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Arrestin_N PF00339.29 KND99273.1 - 8.1e-14 51.9 0.5 2.5e-11 43.8 0.0 3.1 4 0 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KND99273.1 - 0.0048 17.3 0.0 0.1 13.0 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DUF3641 PF12345.8 KND99273.1 - 0.13 12.3 0.3 4.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3641) Arrestin_N PF00339.29 KND99274.1 - 1.6e-07 31.5 0.0 4.7e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain ROF PF07073.12 KND99274.1 - 0.005 17.0 0.1 0.011 15.8 0.1 1.6 1 0 0 1 1 1 1 Modulator of Rho-dependent transcription termination (ROF) Arrestin_C PF02752.22 KND99274.1 - 0.01 16.3 1.3 0.64 10.5 0.6 2.4 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Glyco_hydro_32N PF00251.20 KND99275.1 - 4.1e-84 282.7 3.2 5.8e-84 282.2 3.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KND99275.1 - 9.7e-19 67.9 1.5 1.8e-18 67.0 1.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal MFS_1 PF07690.16 KND99276.1 - 9.2e-19 67.6 21.5 1.4e-18 67.0 21.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KND99276.1 - 9.4e-05 21.4 2.9 9.4e-05 21.4 2.9 1.7 1 1 0 1 1 1 1 MFS_1 like family V_ATPase_I PF01496.19 KND99276.1 - 0.0033 15.4 0.0 0.0051 14.8 0.0 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family BatD PF13584.6 KND99276.1 - 0.23 10.3 0.2 0.38 9.5 0.2 1.4 1 0 0 1 1 1 0 Oxygen tolerance Wzy_C_2 PF11846.8 KND99276.1 - 1 9.3 4.5 1.2 9.0 0.1 2.6 1 1 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal Glyco_hydro81C PF17652.1 KND99277.1 - 2.4e-142 474.3 0.6 3e-142 474.0 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KND99277.1 - 2.1e-81 273.6 0.0 2.6e-81 273.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Arginase PF00491.21 KND99279.1 - 3.1e-86 289.3 0.0 3.9e-86 289.0 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KND99279.1 - 0.017 15.4 0.3 0.029 14.6 0.3 1.3 1 0 0 1 1 1 0 UPF0489 domain DUF5424 PF17462.2 KND99280.1 - 0.22 11.4 0.4 0.51 10.2 0.4 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5424) Arm PF00514.23 KND99281.1 - 1.4e-87 285.3 15.4 1.1e-11 44.3 0.0 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KND99281.1 - 6.1e-23 81.1 4.6 1.2e-22 80.1 3.7 2.0 2 0 0 2 2 2 1 Importin beta binding domain Arm_3 PF16186.5 KND99281.1 - 2.7e-20 71.6 3.3 2.7e-20 71.6 3.3 1.9 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 KND99281.1 - 4.4e-19 68.6 4.5 4.4e-06 27.1 0.1 5.4 3 1 2 5 5 5 4 HEAT-like repeat HEAT_2 PF13646.6 KND99281.1 - 2.4e-12 47.1 0.2 0.0022 18.4 0.0 4.8 1 1 2 4 4 4 2 HEAT repeats HEAT PF02985.22 KND99281.1 - 2.8e-11 42.6 0.5 0.054 13.8 0.0 7.0 8 0 0 8 8 8 2 HEAT repeat Arm_2 PF04826.13 KND99281.1 - 4.1e-06 26.4 0.0 0.07 12.6 0.0 3.8 2 1 2 4 4 4 2 Armadillo-like V-ATPase_H_C PF11698.8 KND99281.1 - 3.7e-05 23.8 0.1 0.77 9.9 0.0 4.2 3 1 1 4 4 4 1 V-ATPase subunit H RICTOR_V PF14668.6 KND99281.1 - 3.9e-05 23.8 0.8 0.4 10.9 0.0 4.8 5 1 1 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 Adaptin_N PF01602.20 KND99281.1 - 9.4e-05 21.1 0.1 0.0065 15.1 0.0 2.4 1 1 1 2 2 2 2 Adaptin N terminal region Atx10homo_assoc PF09759.9 KND99281.1 - 0.0013 18.7 0.1 0.62 10.1 0.0 3.6 3 1 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Usp PF00582.26 KND99283.1 - 1.8e-07 31.8 0.0 5.7e-07 30.1 0.0 1.9 1 1 0 1 1 1 1 Universal stress protein family ADK PF00406.22 KND99283.1 - 0.052 13.7 0.3 0.088 12.9 0.3 1.3 1 0 0 1 1 1 0 Adenylate kinase Peptidase_M14 PF00246.24 KND99284.1 - 6e-67 226.5 0.0 9.3e-67 225.8 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Aldo_ket_red PF00248.21 KND99287.1 - 4.3e-44 150.9 0.3 2.6e-42 145.1 0.3 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family NiFe-hyd_HybE PF11939.8 KND99287.1 - 0.16 11.9 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 [NiFe]-hydrogenase assembly, chaperone, HybE Ras PF00071.22 KND99288.1 - 2.6e-47 160.4 0.0 5.5e-47 159.4 0.0 1.5 1 1 1 2 2 2 1 Ras family Roc PF08477.13 KND99288.1 - 2.8e-33 114.7 0.0 4.1e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND99288.1 - 4.1e-12 45.9 0.0 5.3e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KND99288.1 - 2.6e-07 30.7 0.0 0.02 14.8 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KND99288.1 - 2.5e-06 27.0 0.0 3.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KND99288.1 - 1.2e-05 25.3 0.0 2.1e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KND99288.1 - 3.5e-05 23.9 0.0 0.00058 20.0 0.0 2.1 2 0 0 2 2 2 1 Dynamin family SRPRB PF09439.10 KND99288.1 - 0.00025 20.6 0.0 0.00039 19.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KND99288.1 - 0.00086 18.9 0.0 0.11 12.0 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KND99288.1 - 0.0035 16.9 0.0 0.06 12.9 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 KND99288.1 - 0.0038 17.6 0.0 0.0061 17.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain DLIC PF05783.11 KND99288.1 - 0.013 14.3 0.0 0.029 13.2 0.0 1.3 1 1 0 1 1 1 0 Dynein light intermediate chain (DLIC) Type2_restr_D3 PF16902.5 KND99288.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain AAA_28 PF13521.6 KND99288.1 - 0.16 12.2 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTP_transf_2 PF01909.23 KND99289.1 - 1.8e-14 53.8 0.6 3.5e-13 49.6 0.0 2.6 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 KND99289.1 - 5.9e-14 52.0 0.0 1.4e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 KND99289.1 - 0.00012 22.1 0.1 0.00049 20.1 0.0 2.1 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase TLP-20 PF06088.11 KND99289.1 - 0.085 12.7 0.2 0.085 12.7 0.2 2.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Pkinase PF00069.25 KND99290.1 - 2.4e-23 82.9 0.3 1.1e-16 61.0 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND99290.1 - 2.2e-13 50.1 0.1 5.3e-10 39.0 0.0 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KND99290.1 - 0.057 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KND99290.1 - 0.06 12.1 0.0 0.086 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KND99290.1 - 0.14 12.0 1.1 0.2 11.5 0.2 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF35_N PF12172.8 KND99290.1 - 1.3 9.0 3.8 2.5 8.1 3.8 1.4 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Rif1_N PF12231.8 KND99291.1 - 4.5e-31 108.2 4.5 4.5e-31 108.2 4.5 1.9 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal SIX1_SD PF16878.5 KND99291.1 - 0.13 12.8 0.7 0.52 10.9 0.3 2.4 2 0 0 2 2 2 0 Transcriptional regulator, SIX1, N-terminal SD domain DUF3212 PF11486.8 KND99291.1 - 0.77 9.8 6.3 4.7 7.2 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3212) efThoc1 PF11957.8 KND99293.1 - 1.7e-38 132.6 12.5 1.7e-38 132.6 12.5 1.9 2 0 0 2 2 2 1 THO complex subunit 1 transcription elongation factor GnHR_trans PF12369.8 KND99293.1 - 0.012 16.4 0.2 0.09 13.6 0.0 2.6 2 0 0 2 2 2 0 Gonadotropin hormone receptor transmembrane region RF-1 PF00472.20 KND99294.1 - 2e-21 76.1 0.2 2.7e-21 75.6 0.2 1.1 1 0 0 1 1 1 1 RF-1 domain Redoxin PF08534.10 KND99295.1 - 1.9e-31 108.8 0.0 2.2e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KND99295.1 - 1.7e-08 34.4 0.0 2.2e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DCP1 PF06058.13 KND99296.1 - 5.4e-28 97.3 0.0 8.5e-28 96.6 0.0 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family DUF2185 PF09951.9 KND99296.1 - 0.039 13.8 0.1 0.063 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2185) Spt20 PF12090.8 KND99297.1 - 3.8e-52 177.2 3.4 3.8e-52 177.2 3.4 8.7 3 2 1 4 4 4 1 Spt20 family SEP PF08059.13 KND99297.1 - 1.4 9.6 0.0 1.4 9.6 0.0 4.4 4 1 0 4 4 4 0 SEP domain FHA PF00498.26 KND99298.1 - 3.8e-14 52.8 0.1 7.4e-14 51.9 0.1 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KND99298.1 - 0.038 14.3 0.0 0.14 12.4 0.0 2.0 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain PhyH PF05721.13 KND99299.1 - 1.3e-42 146.4 0.0 1.6e-42 146.2 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Transp_cyt_pur PF02133.15 KND99300.1 - 5.6e-13 48.5 46.5 1.4e-12 47.1 46.5 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3043 PF11241.8 KND99300.1 - 9 6.3 7.4 10 6.1 2.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) SCO1-SenC PF02630.14 KND99301.1 - 8.3e-45 152.0 0.0 1.4e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KND99301.1 - 0.00033 20.6 0.0 0.0005 20.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family PAP_PilO PF06864.12 KND99301.1 - 0.094 11.5 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) SET PF00856.28 KND99303.1 - 1.7e-08 35.0 0.2 4.4e-08 33.7 0.1 1.8 2 0 0 2 2 2 1 SET domain GP24_25 PF17388.2 KND99303.1 - 0.092 12.7 0.1 0.27 11.2 0.1 1.7 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 DUF2735 PF10931.8 KND99304.1 - 0.15 12.8 0.0 0.15 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2735) Pho88 PF10032.9 KND99305.1 - 2.7e-71 238.6 0.0 3e-71 238.4 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) SNase PF00565.17 KND99306.1 - 5.2e-40 136.3 0.0 3.7e-10 40.2 0.0 5.8 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KND99306.1 - 1.4e-13 50.9 0.0 3.6e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 Tudor domain LBR_tudor PF09465.10 KND99306.1 - 0.039 13.8 0.0 0.09 12.6 0.0 1.6 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain HicB-like_2 PF15970.5 KND99306.1 - 0.046 13.9 0.2 0.38 10.9 0.0 2.7 2 0 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system UQ_con PF00179.26 KND99307.1 - 3.2e-50 169.4 0.0 3.6e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Amino_oxidase PF01593.24 KND99308.1 - 2.8e-65 221.4 0.0 3.4e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KND99308.1 - 4.1e-12 46.2 0.0 9.1e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 KND99308.1 - 0.00011 21.2 0.4 0.00022 20.2 0.0 1.6 2 0 0 2 2 2 1 MCRA family DAO PF01266.24 KND99308.1 - 0.00033 20.3 0.0 0.00088 19.0 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KND99308.1 - 0.00099 18.4 0.2 0.87 8.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KND99308.1 - 0.0021 18.0 0.1 0.59 10.1 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 KND99308.1 - 0.0083 14.9 0.1 0.77 8.4 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 KND99308.1 - 0.05 14.2 0.3 0.13 12.8 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KND99308.1 - 0.085 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KND99308.1 - 0.14 11.4 0.1 0.27 10.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KND99308.1 - 0.2 10.9 1.0 0.38 9.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Polysacc_synt_4 PF04669.13 KND99309.1 - 4.8e-20 71.9 2.1 2.5e-18 66.3 2.1 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis Striatin PF08232.12 KND99310.1 - 5.1e-13 49.9 0.1 1.1e-12 48.8 0.1 1.6 1 0 0 1 1 1 1 Striatin family Coatomer_WDAD PF04053.14 KND99310.1 - 0.002 17.3 0.0 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region TPD52 PF04201.15 KND99310.1 - 0.96 9.0 3.9 0.6 9.7 0.7 2.1 2 0 0 2 2 2 0 Tumour protein D52 family ABC_tran PF00005.27 KND99311.1 - 1.8e-51 174.3 0.1 1e-26 94.1 0.0 5.4 4 2 0 4 4 3 2 ABC transporter AAA_21 PF13304.6 KND99311.1 - 9.1e-14 52.0 3.3 0.00053 19.9 1.1 5.0 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KND99311.1 - 5.8e-11 42.3 0.0 0.012 15.0 0.0 4.5 3 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain Chromo PF00385.24 KND99311.1 - 6.2e-09 35.6 0.6 1.5e-08 34.4 0.6 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 KND99311.1 - 9.7e-08 32.8 10.8 0.00047 20.7 0.1 4.0 4 0 0 4 4 4 2 AAA domain MMR_HSR1 PF01926.23 KND99311.1 - 1.1e-07 31.9 0.0 0.0056 16.8 0.0 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KND99311.1 - 1.7e-07 30.9 0.2 0.011 15.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KND99311.1 - 2.1e-06 27.8 0.0 0.019 14.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KND99311.1 - 6.4e-06 26.5 0.3 0.31 11.3 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 KND99311.1 - 2.2e-05 24.8 0.0 0.17 12.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KND99311.1 - 7e-05 23.4 0.3 0.41 11.2 0.0 3.6 3 0 0 3 3 3 1 AAA domain MeaB PF03308.16 KND99311.1 - 0.00012 21.2 0.3 0.34 9.8 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 KND99311.1 - 0.00098 19.3 6.2 0.081 13.0 0.1 4.7 4 1 1 5 5 5 1 Helicase HerA, central domain AAA_16 PF13191.6 KND99311.1 - 0.0011 19.4 0.2 0.2 12.0 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_27 PF13514.6 KND99311.1 - 0.0011 18.6 0.0 1 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KND99311.1 - 0.0012 18.2 0.6 1.9 7.7 0.0 3.6 4 0 0 4 4 3 1 Zeta toxin RNA_helicase PF00910.22 KND99311.1 - 0.0013 19.1 0.0 1.7 9.1 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 KND99311.1 - 0.0017 18.5 0.0 1.1 9.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KND99311.1 - 0.0025 17.5 0.0 1.1 8.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KND99311.1 - 0.0036 17.7 0.4 2.5 8.5 0.0 3.7 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KND99311.1 - 0.0043 16.8 7.1 0.4 10.3 0.3 3.5 3 2 0 3 3 3 2 AAA ATPase domain Dynamin_N PF00350.23 KND99311.1 - 0.0048 17.0 0.9 0.15 12.1 0.0 3.2 3 0 0 3 3 2 1 Dynamin family NACHT PF05729.12 KND99311.1 - 0.018 15.0 0.1 7.5 6.4 0.0 2.6 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 KND99311.1 - 0.022 14.7 0.1 2.9 7.8 0.1 2.9 3 0 0 3 3 2 0 NTPase AAA_24 PF13479.6 KND99311.1 - 0.022 14.5 0.3 1 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KND99311.1 - 0.024 14.6 0.1 0.92 9.4 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain DUF815 PF05673.13 KND99311.1 - 0.024 13.8 0.1 2.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 KND99311.1 - 0.037 13.2 0.1 5.3 6.1 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 KND99311.1 - 0.041 13.9 0.2 1.8 8.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF3361 PF11841.8 KND99311.1 - 0.046 13.7 2.4 1.6 8.6 0.1 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF3361) Roc PF08477.13 KND99311.1 - 0.058 13.6 0.0 6.2 7.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 KND99311.1 - 0.074 13.1 0.1 22 5.1 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Vac14_Fab1_bd PF12755.7 KND99311.1 - 0.085 13.5 0.2 0.37 11.4 0.2 2.1 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KND99311.1 - 0.097 13.0 0.3 34 5.1 0.1 3.9 3 0 0 3 3 3 0 HEAT repeat MukB PF04310.12 KND99311.1 - 0.097 12.5 0.1 13 5.5 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal cobW PF02492.19 KND99311.1 - 0.098 12.2 1.6 10 5.7 0.0 3.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Thymidylate_kin PF02223.17 KND99311.1 - 0.11 12.2 0.2 1.1 8.9 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase Ploopntkinase3 PF18751.1 KND99311.1 - 0.14 12.1 0.0 24 4.8 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_7 PF12775.7 KND99311.1 - 0.17 11.4 0.1 4.5 6.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_13 PF13166.6 KND99311.1 - 1 8.0 8.4 1.5 7.3 0.1 3.2 3 1 1 4 4 4 0 AAA domain Proteasome PF00227.26 KND99312.1 - 2.8e-41 141.1 0.0 3.2e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Utp14 PF04615.13 KND99313.1 - 9e-178 593.3 76.8 9e-178 593.3 76.8 2.2 1 1 1 2 2 2 1 Utp14 protein ALO PF04030.14 KND99314.1 - 3.9e-104 348.1 0.1 1.1e-103 346.6 0.0 1.7 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KND99314.1 - 8.9e-24 83.8 0.0 1.2e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain MciZ PF13072.6 KND99314.1 - 0.043 13.6 0.2 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Mother cell inhibitor of FtsZ HMG_CoA_synt_C PF08540.10 KND99317.1 - 9.9e-105 350.2 4.1 1.2e-104 349.8 4.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KND99317.1 - 6.8e-93 309.4 0.4 1.3e-92 308.4 0.4 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Tubulin_C PF03953.17 KND99320.1 - 2.5e-26 92.3 0.0 3.4e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain TALPID3 PF15324.6 KND99322.1 - 0.019 12.7 2.6 0.019 12.7 2.6 1.1 1 0 0 1 1 1 0 Hedgehog signalling target ChpA-C PF03777.13 KND99322.1 - 5.9 6.9 5.5 3.4e+02 1.2 5.5 2.6 1 1 0 1 1 1 0 ChpA-C NAD_binding_1 PF00175.21 KND99327.1 - 9.7e-29 100.2 0.0 3.5e-28 98.4 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KND99327.1 - 2.7e-27 95.0 0.0 4.6e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KND99327.1 - 3e-05 24.2 0.0 0.0005 20.2 0.0 2.1 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Anoctamin PF04547.12 KND99327.1 - 0.097 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Aldo_ket_red PF00248.21 KND99328.1 - 2.1e-42 145.3 0.0 2.5e-42 145.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-CCCH PF00642.24 KND99329.1 - 4.3e-11 42.4 11.0 1.7e-06 27.8 0.9 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KND99329.1 - 3.2e-06 27.0 13.7 0.00078 19.4 1.3 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 KND99329.1 - 0.022 15.0 2.1 1.2 9.4 0.5 2.6 2 1 0 2 2 2 0 Zinc-finger containing family zf-CCCH_4 PF18044.1 KND99329.1 - 0.032 14.0 11.8 0.41 10.5 1.1 2.5 2 0 0 2 2 2 0 CCCH-type zinc finger Torus PF16131.5 KND99329.1 - 0.48 11.1 0.1 0.48 11.1 0.1 2.9 3 1 0 3 3 3 0 Torus domain Zip PF02535.22 KND99329.1 - 1.3 8.2 3.9 1.7 7.8 3.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Cation_efflux PF01545.21 KND99330.1 - 4.5e-43 147.3 8.9 6.7e-43 146.7 8.9 1.3 1 0 0 1 1 1 1 Cation efflux family CLU PF13236.6 KND99331.1 - 6.8e-73 245.1 0.0 1.5e-72 244.1 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 KND99331.1 - 8.9e-51 172.4 1.4 2.7e-50 170.8 0.0 2.4 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 KND99331.1 - 7e-19 67.9 7.3 7.2e-08 32.6 0.2 4.0 2 2 3 5 5 5 5 Tetratricopeptide repeat CLU_N PF15044.6 KND99331.1 - 3.9e-17 62.4 0.3 1.3e-16 60.7 0.3 2.0 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 KND99331.1 - 7.6e-13 47.9 0.0 0.0047 16.8 0.0 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KND99331.1 - 0.00091 19.2 1.1 1.4 9.2 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF727 PF05303.12 KND99331.1 - 0.002 18.2 1.0 0.017 15.2 0.0 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF727) CAC1F_C PF16885.5 KND99331.1 - 0.024 14.3 1.9 0.11 12.2 0.1 2.5 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term TPR_8 PF13181.6 KND99331.1 - 0.051 13.8 0.7 64 4.1 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat CPSF100_C PF13299.6 KND99331.1 - 0.063 13.5 10.7 0.15 12.2 0.2 3.7 4 0 0 4 4 4 0 Cleavage and polyadenylation factor 2 C-terminal Tim54 PF11711.8 KND99331.1 - 0.087 11.6 14.1 0.031 13.1 0.7 2.8 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 BSMAP PF12280.8 KND99331.1 - 0.11 12.8 1.8 12 6.0 0.1 2.8 2 0 0 2 2 2 0 Brain specific membrane anchored protein SET PF00856.28 KND99331.1 - 0.12 12.7 3.5 1.7 9.0 0.1 3.2 3 0 0 3 3 3 0 SET domain RXT2_N PF08595.11 KND99331.1 - 1.6 8.7 11.8 7.3 6.6 1.1 2.9 2 0 0 2 2 2 0 RXT2-like, N-terminal RP-C_C PF11800.8 KND99331.1 - 2.7 8.1 9.2 17 5.4 3.3 3.3 3 0 0 3 3 3 0 Replication protein C C-terminal region RasGAP PF00616.19 KND99331.1 - 6.1 6.5 16.3 0.083 12.6 1.9 3.5 3 0 0 3 3 3 0 GTPase-activator protein for Ras-like GTPase DUF4471 PF14740.6 KND99331.1 - 6.8 5.8 9.8 24 4.0 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) F-box-like PF12937.7 KND99332.1 - 2.4e-09 36.9 0.1 5.2e-09 35.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KND99332.1 - 1e-07 31.6 0.3 2.1e-07 30.6 0.3 1.6 1 0 0 1 1 1 1 F-box domain UIM PF02809.20 KND99332.1 - 0.0096 15.8 13.7 0.015 15.2 3.2 3.5 3 0 0 3 3 3 1 Ubiquitin interaction motif WD40_like PF17005.5 KND99332.1 - 0.1 11.9 0.1 0.54 9.5 0.1 2.1 2 1 1 3 3 3 0 WD40-like domain RPM2 PF08579.11 KND99333.1 - 6.8e-24 84.6 4.2 9.5e-24 84.1 0.7 2.9 2 0 0 2 2 2 1 Mitochondrial ribonuclease P subunit (RPM2) DUF5340 PF17275.2 KND99333.1 - 0.0047 17.0 0.2 0.028 14.5 0.2 2.3 2 0 0 2 2 2 1 Family of unknown function (DUF5340) PPR_2 PF13041.6 KND99333.1 - 0.042 14.1 0.3 20 5.5 0.0 4.5 5 0 0 5 5 5 0 PPR repeat family Mannosyl_trans3 PF11051.8 KND99334.1 - 5e-66 222.9 0.0 8.2e-66 222.2 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Adaptin_N PF01602.20 KND99335.1 - 6.7e-92 308.7 22.7 1.1e-91 308.1 22.7 1.3 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KND99335.1 - 5.9e-45 153.1 2.6 7.3e-45 152.8 0.8 2.1 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KND99335.1 - 2.9e-28 98.3 0.0 9.4e-28 96.7 0.0 2.0 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform Cnd1 PF12717.7 KND99335.1 - 3.8e-13 49.8 17.2 7.5e-06 26.1 0.2 5.8 6 1 0 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KND99335.1 - 6e-12 45.8 0.1 1.3e-06 28.7 0.0 4.8 3 1 2 5 5 5 2 HEAT repeats HEAT PF02985.22 KND99335.1 - 0.00076 19.5 5.1 7 7.2 0.1 6.3 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 KND99335.1 - 0.032 14.7 2.6 0.99 10.0 0.1 3.9 4 0 0 4 4 4 0 HEAT-like repeat Man-6-P_recep PF02157.15 KND99336.1 - 2.7e-11 43.1 0.0 3.9e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.18 KND99336.1 - 4.9e-10 39.7 0.5 1.3e-05 25.3 0.2 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 KND99336.1 - 1.5e-05 25.0 0.0 2.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein 27 PRKCSH_1 PF13015.6 KND99336.1 - 0.0065 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF4131 PF13567.6 KND99336.1 - 0.12 12.0 0.9 4.5 6.9 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DIL PF01843.19 KND99337.1 - 9.6e-21 74.0 3.5 1.8e-19 70.0 3.5 2.7 1 1 0 1 1 1 1 DIL domain Ank_5 PF13857.6 KND99337.1 - 1.6e-08 34.6 0.0 0.007 16.7 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KND99337.1 - 1.1e-07 31.9 0.0 0.0035 17.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KND99337.1 - 2.1e-07 31.4 0.0 9.7e-07 29.3 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND99337.1 - 2.7e-06 27.3 0.0 0.0037 17.6 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KND99337.1 - 2.9e-05 24.5 0.5 0.00073 20.1 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ribosomal_L37 PF08561.10 KND99338.1 - 2e-20 73.5 7.6 1.1e-16 61.4 0.3 2.0 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 YchF-GTPase_C PF06071.13 KND99339.1 - 1.9e-36 124.1 0.3 4.3e-36 122.9 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KND99339.1 - 1.7e-16 60.3 0.0 8.1e-16 58.1 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KND99339.1 - 0.0057 16.2 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 KND99339.1 - 0.0059 16.6 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 TGS domain MTCP1 PF08991.10 KND99341.1 - 2.6e-28 98.0 13.1 3e-28 97.8 13.1 1.0 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 KND99341.1 - 0.0022 18.1 4.5 0.0022 18.1 4.5 1.9 2 1 0 2 2 2 1 CHCH domain Cmc1 PF08583.10 KND99341.1 - 0.38 10.8 8.5 0.14 12.2 2.0 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF1640 PF07798.11 KND99342.1 - 2.7e-32 112.2 3.3 3.8e-32 111.7 3.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF4972 PF16342.5 KND99342.1 - 0.065 12.9 0.3 0.065 12.9 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4972) Hs1pro-1_C PF07014.12 KND99344.1 - 0.077 12.5 0.2 0.17 11.3 0.2 1.6 1 1 1 2 2 2 0 Hs1pro-1 protein C-terminus Pkinase PF00069.25 KND99345.1 - 7.3e-06 25.5 0.0 1.6e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Cnd1 PF12717.7 KND99345.1 - 7.9e-05 22.8 1.0 0.00031 20.8 0.3 2.2 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KND99345.1 - 0.00026 19.7 0.3 0.00048 18.8 0.3 1.4 1 0 0 1 1 1 1 Adaptin N terminal region COMPASS-Shg1 PF05205.12 KND99345.1 - 0.47 11.2 2.1 0.59 10.9 0.1 2.2 3 0 0 3 3 3 0 COMPASS (Complex proteins associated with Set1p) component shg1 OPT PF03169.15 KND99347.1 - 2e-173 578.4 42.5 2.3e-173 578.2 42.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein p450 PF00067.22 KND99348.1 - 2.4e-64 217.8 0.0 3.2e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cellulase PF00150.18 KND99350.1 - 2.7e-08 33.6 3.5 8.6e-08 31.9 0.0 2.7 2 1 0 3 3 3 1 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.16 KND99353.1 - 9e-16 57.7 36.8 1.2e-12 47.4 20.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ninjurin PF04923.12 KND99353.1 - 0.02 14.8 0.3 6.5 6.8 0.1 3.8 4 0 0 4 4 4 0 Ninjurin DUF624 PF04854.14 KND99353.1 - 0.024 14.7 0.3 0.024 14.7 0.3 3.1 4 1 0 4 4 4 0 Protein of unknown function, DUF624 DUF4225 PF13988.6 KND99353.1 - 0.71 9.4 4.2 9.9 5.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) MFS_1 PF07690.16 KND99354.1 - 2.4e-12 46.5 36.6 4.7e-10 38.9 35.6 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MatE PF01554.18 KND99358.1 - 7.9e-46 155.6 28.7 7.1e-32 110.3 11.6 2.4 3 0 0 3 3 3 2 MatE MFS_1 PF07690.16 KND99359.1 - 2.4e-07 30.0 3.7 1.9e-06 27.1 5.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Exosortase_EpsH PF09721.10 KND99359.1 - 0.18 11.3 5.7 0.23 11.0 5.7 1.1 1 0 0 1 1 1 0 Transmembrane exosortase (Exosortase_EpsH) MFS_1 PF07690.16 KND99360.1 - 1.2e-23 83.6 8.6 1.6e-23 83.3 8.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.9 KND99360.1 - 0.0074 16.5 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ERGIC_N PF13850.6 KND99360.1 - 0.13 12.7 4.4 0.42 11.0 0.0 3.1 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) MHYT PF03707.16 KND99360.1 - 0.63 10.3 6.4 0.5 10.6 2.8 2.2 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat Band_7_C PF16200.5 KND99361.1 - 0.24 11.5 1.3 0.77 9.9 0.1 2.1 2 0 0 2 2 2 0 C-terminal region of band_7 AcetylCoA_hydro PF02550.15 KND99362.1 - 7.6e-64 215.3 0.0 1.2e-63 214.6 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KND99362.1 - 1.8e-41 141.7 0.0 2.8e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DnaJ_C PF01556.18 KND99363.1 - 8.7e-31 107.0 0.1 1.3e-30 106.5 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KND99363.1 - 8.7e-24 83.4 5.9 1.8e-23 82.4 5.9 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KND99363.1 - 4.3e-12 46.2 17.7 7.7e-12 45.4 17.7 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KND99363.1 - 0.014 15.4 16.4 0.019 14.9 4.9 3.9 2 1 2 4 4 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF5351 PF17302.2 KND99363.1 - 4.3 7.6 20.0 2.7 8.2 0.2 4.2 4 0 0 4 4 4 0 Family of unknown function (DUF5351) HypA PF01155.19 KND99363.1 - 6.1 6.9 7.6 10 6.2 5.7 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 KND99363.1 - 7.3 6.9 5.7 29 5.0 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon Ran_BP1 PF00638.18 KND99364.1 - 5.9e-15 55.6 0.0 9.4e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 KND99364.1 - 2.1e-08 34.7 0.0 5.1e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 NUP50 (Nucleoporin 50 kDa) Metaviral_G PF09595.10 KND99364.1 - 0.082 13.0 7.3 0.09 12.9 6.0 1.7 1 1 1 2 2 2 0 Metaviral_G glycoprotein Ribosomal_S25 PF03297.15 KND99365.1 - 4.6e-41 139.1 3.8 5.1e-41 139.0 3.8 1.0 1 0 0 1 1 1 1 S25 ribosomal protein FtsK_gamma PF09397.10 KND99365.1 - 0.0054 16.5 0.0 0.0077 16.0 0.0 1.3 1 0 0 1 1 1 1 Ftsk gamma domain DUF365 PF04033.12 KND99365.1 - 0.027 14.7 0.1 0.039 14.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF365) HTH_CodY PF08222.11 KND99365.1 - 0.049 13.2 0.1 0.077 12.6 0.1 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain EAP30 PF04157.16 KND99365.1 - 0.087 12.1 0.0 0.096 12.0 0.0 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family Polyketide_cyc PF03364.20 KND99366.1 - 1.1e-12 48.3 0.1 1.4e-12 47.9 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KND99366.1 - 0.0021 18.3 0.0 0.0028 17.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport A_amylase_inhib PF01356.19 KND99366.1 - 0.057 13.4 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha amylase inhibitor PH_9 PF15410.6 KND99367.1 - 4.5e-05 23.8 0.2 0.0073 16.7 0.0 2.9 3 0 0 3 3 3 2 Pleckstrin homology domain PH PF00169.29 KND99367.1 - 0.067 13.7 0.0 3.5 8.2 0.0 2.8 2 0 0 2 2 2 0 PH domain CENP-B_dimeris PF09026.10 KND99367.1 - 7.4 7.0 13.6 15 6.0 13.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GRDA PF04723.14 KND99368.1 - 0.19 11.5 1.3 0.2 11.4 1.3 1.0 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A Pcc1 PF09341.10 KND99369.1 - 2e-18 66.3 0.1 2.3e-18 66.1 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 DNApol_Exo PF18136.1 KND99370.1 - 5.2e-99 330.9 0.1 7.9e-99 330.3 0.1 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KND99370.1 - 1.1e-52 179.4 0.1 1.9e-52 178.6 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 KND99370.1 - 0.1 12.3 0.1 0.66 9.7 0.0 2.1 2 0 0 2 2 2 0 3'-5' exonuclease PDDEXK_10 PF07788.11 KND99372.1 - 0.016 15.2 0.1 0.035 14.0 0.1 1.6 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily SBP_bac_5 PF00496.22 KND99372.1 - 0.12 11.3 0.2 0.18 10.7 0.2 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle CENP-B_dimeris PF09026.10 KND99372.1 - 1.3 9.4 8.8 15 6.0 6.6 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PWWP PF00855.17 KND99375.1 - 3.9e-17 62.4 0.2 9.6e-17 61.2 0.2 1.7 1 0 0 1 1 1 1 PWWP domain Med26 PF08711.11 KND99375.1 - 1.5e-08 34.5 1.2 1.9e-08 34.2 0.1 1.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain PI3K_1B_p101 PF10486.9 KND99375.1 - 0.039 11.8 5.1 0.05 11.4 5.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit eIF-5a PF01287.20 KND99378.1 - 1.8e-30 104.8 1.0 2.5e-30 104.4 1.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KND99378.1 - 0.0091 16.0 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain zf-RING_2 PF13639.6 KND99381.1 - 1.1e-12 48.1 6.8 1.8e-12 47.4 6.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KND99381.1 - 1.6e-08 34.3 5.7 2.7e-08 33.5 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KND99381.1 - 1.3e-07 31.2 2.6 1.3e-07 31.2 2.6 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KND99381.1 - 3.8e-07 30.0 4.3 4.4e-06 26.6 1.2 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KND99381.1 - 6.8e-07 29.1 4.9 1.3e-06 28.2 4.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KND99381.1 - 1.6e-06 28.3 6.9 5.2e-06 26.7 6.9 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KND99381.1 - 2.8e-06 27.1 5.2 5.3e-06 26.2 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KND99381.1 - 4.7e-05 23.4 1.8 8.7e-05 22.5 1.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KND99381.1 - 0.00037 20.3 4.2 0.00061 19.6 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KND99381.1 - 0.0095 15.5 5.2 0.018 14.6 5.2 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KND99381.1 - 0.015 15.2 5.0 0.031 14.1 5.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zf_RING PF16744.5 KND99381.1 - 0.024 14.8 0.8 0.024 14.8 0.8 2.3 1 1 1 2 2 2 0 KIAA1045 RING finger PHD PF00628.29 KND99381.1 - 0.028 14.3 5.6 0.054 13.4 5.6 1.5 1 0 0 1 1 1 0 PHD-finger Rtf2 PF04641.12 KND99381.1 - 0.07 12.5 0.1 0.07 12.5 0.1 2.8 2 1 1 3 3 3 0 Rtf2 RING-finger Plasmodium_Vir PF05795.11 KND99381.1 - 0.1 12.0 7.2 0.49 9.8 0.3 2.3 2 0 0 2 2 2 0 Plasmodium vivax Vir protein zf-C3H2C3 PF17122.5 KND99381.1 - 0.8 9.8 3.9 2.5 8.2 3.9 1.9 1 0 0 1 1 1 0 Zinc-finger RINGv PF12906.7 KND99381.1 - 0.87 9.8 6.8 1.7 8.8 6.8 1.5 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 KND99381.1 - 3 7.9 6.6 0.3 11.0 1.0 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 KND99381.1 - 3.5 7.5 7.0 7.4 6.4 7.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 KND99383.1 - 7.7e-11 41.7 0.0 1.5e-10 40.7 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KND99383.1 - 0.06 13.5 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Fmp27 PF10344.9 KND99385.1 - 1.1e-95 321.6 12.8 1.1e-95 321.6 12.8 2.3 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 KND99385.1 - 9.6e-92 308.3 20.2 9.6e-92 308.3 20.2 1.8 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 KND99385.1 - 8.8e-61 206.2 21.7 1.7e-36 126.1 0.2 3.6 2 1 0 3 3 3 2 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 KND99385.1 - 1.2e-52 178.1 0.0 1.5e-51 174.6 0.0 2.7 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KND99385.1 - 1.7e-43 148.2 0.5 7.9e-43 146.0 0.5 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 KND99385.1 - 3.9e-24 85.3 0.6 4.4e-23 81.9 0.0 3.2 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain Vps4_C PF09336.10 KND99385.1 - 0.085 12.9 0.3 0.42 10.7 0.1 2.3 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Ribosomal_L32e PF01655.18 KND99389.1 - 3.4e-11 43.5 2.0 3.8e-11 43.4 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Pkinase PF00069.25 KND99390.1 - 4.9e-38 131.0 0.0 6.7e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND99390.1 - 9.1e-23 80.8 0.0 1.6e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND99390.1 - 2.6e-08 33.5 0.0 4.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 KND99390.1 - 0.0061 16.1 0.0 0.031 13.8 0.0 1.9 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL FTA2 PF13095.6 KND99390.1 - 0.0086 15.7 0.4 0.21 11.2 0.0 2.2 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KND99390.1 - 0.026 13.9 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KND99390.1 - 0.11 11.6 0.1 0.21 10.6 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KND99390.1 - 0.14 12.1 0.2 0.24 11.3 0.2 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family SUR7 PF06687.12 KND99393.1 - 2.4e-33 115.6 14.0 2.9e-33 115.3 14.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF2301 PF10063.9 KND99393.1 - 0.0079 16.6 1.6 0.0079 16.6 1.6 1.7 2 0 0 2 2 2 1 Uncharacterized integral membrane protein (DUF2301) Claudin_3 PF06653.11 KND99393.1 - 4.9 7.1 12.2 0.18 11.7 6.3 1.6 2 0 0 2 2 2 0 Tight junction protein, Claudin-like Lipase_3 PF01764.25 KND99394.1 - 4.8e-07 29.7 0.0 1.2e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KND99394.1 - 0.0098 16.5 0.0 0.02 15.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KND99394.1 - 0.045 13.5 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.12 KND99394.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) HMG_box PF00505.19 KND99395.1 - 3.2e-07 30.6 1.4 8.1e-07 29.4 1.4 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box Phos_pyr_kin PF08543.12 KND99395.1 - 2e-05 24.1 0.0 3.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KND99395.1 - 0.037 13.3 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 pfkB family carbohydrate kinase ANAPC4_WD40 PF12894.7 KND99396.1 - 5.2e-06 26.7 0.0 0.0054 17.0 0.0 2.9 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KND99396.1 - 0.0086 16.9 0.2 0.077 13.9 0.0 2.8 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF4432 PF14486.6 KND99396.1 - 0.86 8.3 4.2 1.8 7.3 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4432) SAP PF02037.27 KND99398.1 - 2.8e-06 27.0 0.0 6.1e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 SAP domain zf-Di19 PF05605.12 KND99398.1 - 0.0033 17.7 0.6 0.39 11.0 0.2 2.8 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-WRNIP1_ubi PF18279.1 KND99398.1 - 0.03 14.9 1.3 0.075 13.7 0.1 2.2 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Zn-C2H2_12 PF18112.1 KND99398.1 - 0.11 13.0 1.2 11 6.5 0.1 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2HC_2 PF13913.6 KND99398.1 - 0.15 12.0 0.3 0.15 12.0 0.3 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Sgf11 PF08209.11 KND99398.1 - 9.4 5.9 8.8 0.55 9.8 1.3 2.5 2 1 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Form_Nir_trans PF01226.17 KND99400.1 - 1.7e-60 204.3 24.6 2.2e-60 204.0 24.6 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter DEAD PF00270.29 KND99401.1 - 1.5e-38 132.3 1.6 2.4e-38 131.6 1.6 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND99401.1 - 2.2e-32 111.7 1.9 2.8e-29 101.7 0.0 2.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 KND99401.1 - 2.9e-07 30.6 0.0 6.5e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KND99401.1 - 0.0043 17.3 0.2 0.011 16.0 0.2 1.7 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 KND99401.1 - 0.023 14.7 1.0 0.059 13.4 0.1 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain DnaI_N PF07319.11 KND99401.1 - 0.059 14.0 0.1 3.1 8.5 0.0 2.9 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus Mpv17_PMP22 PF04117.12 KND99402.1 - 1.8e-05 24.9 7.9 4.7e-05 23.5 7.4 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family YL1 PF05764.13 KND99406.1 - 9.1e-37 127.5 58.9 9.1e-37 127.5 58.9 5.9 3 2 0 4 4 4 1 YL1 nuclear protein YL1_C PF08265.11 KND99406.1 - 1.6e-09 37.4 0.2 4.1e-09 36.0 0.2 1.8 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Methyltransf_23 PF13489.6 KND99407.1 - 1.1e-21 77.4 0.0 1.6e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND99407.1 - 2.2e-15 57.2 0.0 1.2e-14 54.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND99407.1 - 1.2e-14 54.7 0.0 2.5e-14 53.7 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND99407.1 - 4.1e-11 43.4 0.0 7.3e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND99407.1 - 5.1e-11 42.6 0.0 8.9e-11 41.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KND99407.1 - 4.9e-06 26.0 0.0 6.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KND99407.1 - 0.00011 21.7 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 KND99407.1 - 0.00034 20.3 0.0 0.00051 19.7 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 KND99407.1 - 0.0041 16.1 0.0 0.0071 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 KND99407.1 - 0.0045 16.4 0.0 0.0061 15.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 KND99407.1 - 0.015 14.9 0.0 0.04 13.5 0.0 1.6 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW DREV PF05219.12 KND99407.1 - 0.015 14.4 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase FliG_N PF14842.6 KND99407.1 - 0.07 13.7 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 FliG N-terminal domain MTS PF05175.14 KND99407.1 - 0.084 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain CAP_N PF01213.19 KND99408.1 - 3.5e-112 375.0 0.6 5e-112 374.5 0.6 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KND99408.1 - 1.7e-52 177.2 3.4 2.5e-52 176.7 3.4 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Actin PF00022.19 KND99409.1 - 2.5e-47 161.4 0.0 3.3e-25 88.6 0.0 2.4 2 0 0 2 2 2 2 Actin Methyltr_RsmB-F PF01189.17 KND99410.1 - 1.7e-82 275.9 0.0 3.9e-82 274.7 0.0 1.6 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KND99410.1 - 3.2e-08 33.9 0.0 1.1e-07 32.2 0.0 2.0 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF DUF2431 PF10354.9 KND99410.1 - 0.0093 16.2 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) FtsJ PF01728.19 KND99410.1 - 0.017 15.2 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Bradykinin PF06753.12 KND99410.1 - 2 8.2 4.3 3.9 7.3 4.3 1.5 1 0 0 1 1 1 0 Bradykinin PIEZO PF15917.5 KND99410.1 - 2.1 7.8 8.6 7.5 6.0 8.6 1.9 1 0 0 1 1 1 0 Piezo Gcd10p PF04189.13 KND99411.1 - 4.8e-98 328.0 2.1 6.6e-98 327.5 2.1 1.2 1 0 0 1 1 1 1 Gcd10p family AvrM_N PF18247.1 KND99411.1 - 0.00012 21.9 0.3 0.00037 20.4 0.3 1.8 1 0 0 1 1 1 1 Flax-rust effector AvrM N-terminal domain z-alpha PF02295.17 KND99411.1 - 0.021 14.9 0.3 0.055 13.5 0.3 1.7 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain NTase_sub_bind PF08780.11 KND99411.1 - 0.06 13.3 2.2 0.11 12.5 2.2 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase substrate binding protein like MTS PF05175.14 KND99412.1 - 4.5e-14 52.3 0.0 6.7e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KND99412.1 - 3e-10 40.7 0.0 5.5e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND99412.1 - 9.2e-10 38.5 0.0 1.4e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KND99412.1 - 4.7e-07 29.5 0.0 7e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KND99412.1 - 7e-07 29.8 0.0 1.4e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmC_N PF17827.1 KND99412.1 - 0.00083 19.9 0.1 0.0019 18.7 0.1 1.6 1 0 0 1 1 1 1 PrmC N-terminal domain N6_Mtase PF02384.16 KND99412.1 - 0.0011 18.3 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_15 PF09445.10 KND99412.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Ubie_methyltran PF01209.18 KND99412.1 - 0.0013 18.1 0.1 0.0019 17.5 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KND99412.1 - 0.0013 18.6 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 KND99412.1 - 0.0053 16.5 0.0 0.0088 15.7 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 KND99412.1 - 0.0061 17.3 0.1 0.014 16.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KND99412.1 - 0.014 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 KND99412.1 - 0.015 15.2 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AviRa PF11599.8 KND99412.1 - 0.04 13.4 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Methyltransf_32 PF13679.6 KND99412.1 - 0.061 13.3 0.0 0.097 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_10 PF05971.12 KND99412.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 RNA methyltransferase Eco57I PF07669.11 KND99412.1 - 0.14 12.6 0.0 0.79 10.3 0.0 2.1 2 0 0 2 2 2 0 Eco57I restriction-modification methylase TRM PF02005.16 KND99412.1 - 0.21 10.7 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase S4 PF01479.25 KND99413.1 - 3e-16 58.8 0.0 6.6e-16 57.8 0.0 1.6 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 KND99413.1 - 0.005 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 S4 domain Eaf7 PF07904.13 KND99414.1 - 3.3e-17 62.8 0.3 3.3e-17 62.8 0.3 2.8 2 1 0 2 2 2 1 Chromatin modification-related protein EAF7 AA_permease PF00324.21 KND99416.1 - 7.1e-126 420.6 49.8 8.9e-126 420.3 49.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND99416.1 - 5.4e-33 114.4 54.8 7e-33 114.1 54.8 1.2 1 0 0 1 1 1 1 Amino acid permease MitoNEET_N PF10660.9 KND99416.1 - 0.24 11.5 2.3 4 7.6 0.2 3.2 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus SUN PF03856.13 KND99421.1 - 2.8e-97 325.0 15.1 3.6e-97 324.6 15.1 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Glyco_hydro2_C5 PF18565.1 KND99421.1 - 0.15 11.9 0.0 0.47 10.3 0.0 1.8 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 Gar1 PF04410.14 KND99423.1 - 2.2e-44 150.9 3.0 2.2e-44 150.9 3.0 3.0 2 1 0 2 2 2 1 Gar1/Naf1 RNA binding region MutS_V PF00488.21 KND99424.1 - 9.3e-68 228.0 0.0 1.7e-67 227.1 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KND99424.1 - 9e-25 88.0 6.9 9e-25 88.0 6.9 2.4 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.20 KND99424.1 - 6.2e-24 84.4 0.0 3e-23 82.2 0.0 2.2 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 KND99424.1 - 4e-11 43.4 0.0 1.1e-10 42.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain II N-SET PF11764.8 KND99425.1 - 1.3e-47 162.1 1.8 1.3e-47 162.1 1.8 3.2 4 0 0 4 4 4 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 KND99425.1 - 1.7e-25 88.4 1.8 3.9e-25 87.3 1.8 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.28 KND99425.1 - 1.8e-19 70.8 0.1 1.8e-19 70.8 0.1 3.6 2 1 0 3 3 3 1 SET domain ETC_C1_NDUFA4 PF04800.12 KND99426.1 - 3.3e-33 113.8 1.5 4.2e-33 113.5 1.5 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region ORC6 PF05460.13 KND99427.1 - 2.7e-70 237.4 0.0 3.4e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) PDZ_1 PF12812.7 KND99428.1 - 9.5e-52 172.9 0.0 1.5e-35 121.0 0.0 3.0 3 0 0 3 3 3 2 PDZ-like domain Trypsin_2 PF13365.6 KND99428.1 - 7.5e-25 88.6 0.1 2.1e-19 70.9 0.0 2.7 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.6 KND99428.1 - 4.6e-11 42.9 1.1 0.079 13.3 0.0 4.4 4 0 0 4 4 4 3 PDZ domain PDZ_6 PF17820.1 KND99428.1 - 1.4e-09 37.6 0.3 1.9e-06 27.6 0.0 3.7 4 0 0 4 4 4 1 PDZ domain PDZ PF00595.24 KND99428.1 - 2.6e-07 30.9 0.0 1.4e-05 25.3 0.0 2.9 3 0 0 3 3 3 1 PDZ domain Trypsin PF00089.26 KND99428.1 - 1e-05 25.5 0.0 3.1e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Trypsin Peptidase_S7 PF00949.21 KND99428.1 - 0.0014 18.5 0.1 0.0031 17.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Tricorn_PDZ PF14685.6 KND99428.1 - 0.0032 17.4 0.0 4.6 7.3 0.0 3.6 4 0 0 4 4 4 1 Tricorn protease PDZ domain DUF31 PF01732.16 KND99428.1 - 0.0069 16.0 0.4 0.011 15.4 0.4 1.2 1 0 0 1 1 1 1 Putative peptidase (DUF31) Peptidase_S46 PF10459.9 KND99428.1 - 0.024 13.3 1.9 0.035 12.8 0.1 1.9 2 0 0 2 2 2 0 Peptidase S46 Ribosomal_L35p PF01632.19 KND99429.1 - 2.2e-08 34.5 6.2 2.7e-08 34.2 6.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L35 Frag1 PF10277.9 KND99430.1 - 1.4e-38 132.6 13.0 1.4e-38 132.6 13.0 3.2 3 2 1 4 4 4 1 Frag1/DRAM/Sfk1 family NDUFB10 PF10249.9 KND99431.1 - 0.0067 16.9 0.0 0.0068 16.9 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 ATP-synt PF00231.19 KND99433.1 - 1.6e-76 257.7 9.7 1.8e-76 257.5 9.7 1.0 1 0 0 1 1 1 1 ATP synthase NTS PF15447.6 KND99433.1 - 0.025 15.1 0.3 0.12 12.9 0.0 2.1 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 EMP70 PF02990.16 KND99434.1 - 7.1e-137 457.2 16.3 8.6e-137 456.9 16.3 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF962 PF06127.11 KND99434.1 - 0.0099 15.9 0.6 0.14 12.3 0.0 3.1 2 2 0 2 2 2 1 Protein of unknown function (DUF962) TPR_1 PF00515.28 KND99435.1 - 1.6e-36 122.6 12.2 8.6e-08 31.7 0.0 9.2 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 KND99435.1 - 7.9e-35 116.2 11.7 5.8e-05 22.9 0.0 10.0 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 KND99435.1 - 1.1e-30 103.2 12.6 1.5e-05 24.8 0.0 9.0 9 0 0 9 9 9 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KND99435.1 - 1.7e-21 76.3 25.3 2.3e-16 59.8 1.7 4.3 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KND99435.1 - 3.1e-18 65.2 14.2 0.0021 17.7 0.2 8.3 6 1 3 9 9 9 4 TPR repeat TPR_17 PF13431.6 KND99435.1 - 5e-16 57.8 16.1 0.25 11.8 0.1 9.4 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 KND99435.1 - 1.9e-14 53.7 6.6 0.073 13.4 0.3 7.2 8 1 0 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 KND99435.1 - 4.3e-14 52.0 3.7 0.0081 16.9 0.1 8.2 6 2 3 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 KND99435.1 - 3.4e-13 48.6 2.4 0.21 11.7 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KND99435.1 - 5.3e-12 46.2 12.3 0.019 15.6 0.0 7.0 6 2 2 8 8 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 KND99435.1 - 1.1e-11 44.8 0.7 5.9e-05 23.1 0.0 5.0 4 3 2 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KND99435.1 - 4.1e-11 43.2 10.4 0.82 10.2 1.7 7.4 5 2 1 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 KND99435.1 - 3.3e-08 33.6 8.6 1.4 9.7 0.0 7.6 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_3 PF07720.12 KND99435.1 - 6.2e-05 22.9 0.7 0.013 15.4 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR PF01535.20 KND99435.1 - 0.22 11.9 4.6 2.8 8.4 0.0 4.5 5 0 0 5 5 5 0 PPR repeat PH PF00169.29 KND99437.1 - 1.5e-14 54.3 0.0 4.7e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.6 KND99437.1 - 8.3e-10 38.4 0.0 2e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KND99437.1 - 8.3e-09 34.9 0.0 2e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.17 KND99437.1 - 6.4e-07 29.4 0.0 1.7e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 KND99437.1 - 0.00015 21.4 0.0 0.00034 20.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 KND99437.1 - 0.00048 20.5 0.4 0.013 15.9 0.4 2.9 1 1 0 1 1 1 1 Pleckstrin homology domain SAM_1 PF00536.30 KND99437.1 - 0.004 17.6 0.1 0.0081 16.6 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) BORCS8 PF10167.9 KND99437.1 - 0.11 12.5 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 8 Agenet PF05641.12 KND99437.1 - 0.16 12.5 0.1 0.4 11.2 0.1 1.7 1 0 0 1 1 1 0 Agenet domain Titin_Z PF09042.11 KND99437.1 - 1.2 9.1 3.1 5 7.2 0.7 2.6 2 0 0 2 2 2 0 Titin Z MFS_1 PF07690.16 KND99441.1 - 1e-36 126.6 24.8 1e-36 126.6 24.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily SpoVAB PF13782.6 KND99441.1 - 4.2 7.7 8.6 0.086 13.1 0.7 2.2 2 1 1 3 3 3 0 Stage V sporulation protein AB PAP1 PF08601.10 KND99443.1 - 1.5e-23 84.2 17.7 7.9e-21 75.2 2.1 2.7 2 2 0 2 2 2 2 Transcription factor PAP1 bZIP_1 PF00170.21 KND99443.1 - 1.4e-08 34.7 10.2 2.9e-08 33.7 10.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KND99443.1 - 4.4e-05 23.5 12.1 9.3e-05 22.4 12.1 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KND99443.1 - 0.0051 17.3 10.3 0.0095 16.4 10.3 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor KASH_CCD PF14662.6 KND99443.1 - 0.012 15.5 2.8 0.02 14.7 2.8 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DivIC PF04977.15 KND99443.1 - 0.23 11.3 3.2 0.44 10.4 3.2 1.4 1 0 0 1 1 1 0 Septum formation initiator SHE3 PF17078.5 KND99443.1 - 0.3 10.8 4.3 0.2 11.3 2.3 1.6 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Med21 PF11221.8 KND99443.1 - 1.9 8.7 6.1 6.2 7.1 5.2 2.4 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Mak10 PF04112.13 KND99445.1 - 3.4e-35 121.0 0.6 3.6e-34 117.7 0.0 2.6 3 0 0 3 3 3 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Cnd3 PF12719.7 KND99446.1 - 1.3e-80 270.8 1.5 1.8e-79 267.0 1.4 2.5 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KND99446.1 - 5e-07 30.0 1.9 0.0032 17.8 0.4 5.3 3 2 2 5 5 5 2 HEAT repeats HEAT PF02985.22 KND99446.1 - 3.9e-06 26.7 0.7 1.5 9.2 0.0 5.7 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 KND99446.1 - 0.052 13.6 6.8 0.35 10.9 0.1 4.8 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Sterol_MT_C PF08498.10 KND99447.1 - 6.3e-27 93.7 0.5 9.8e-27 93.1 0.5 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KND99447.1 - 2.6e-18 66.4 0.0 4.8e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND99447.1 - 1.1e-16 61.3 0.0 2.7e-16 60.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND99447.1 - 8.7e-15 54.8 0.0 1.3e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KND99447.1 - 7.1e-11 41.9 0.6 9.7e-11 41.5 0.6 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KND99447.1 - 8.7e-11 42.5 0.0 1.7e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND99447.1 - 2.2e-10 40.6 0.0 3.3e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KND99447.1 - 4.1e-07 29.6 0.0 6.8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 KND99447.1 - 0.00015 21.4 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 KND99447.1 - 0.0018 17.7 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KND99447.1 - 0.015 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KND99447.1 - 0.021 14.4 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_29 PF03141.16 KND99447.1 - 0.028 13.0 0.0 0.041 12.4 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.6 KND99447.1 - 0.059 13.4 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 KND99447.1 - 0.068 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Glyco_hydro_76 PF03663.14 KND99449.1 - 1.3e-37 130.2 0.6 1.7e-37 129.8 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KND99449.1 - 1e-05 24.8 1.8 0.1 11.6 0.1 3.0 1 1 2 3 3 3 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 KND99449.1 - 0.00041 19.9 0.0 0.001 18.6 0.0 1.6 2 0 0 2 2 2 1 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_127 PF07944.12 KND99449.1 - 0.0028 16.2 0.1 0.25 9.8 0.0 2.2 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 GlcNAc_2-epim PF07221.11 KND99449.1 - 0.0028 16.9 0.1 0.021 14.1 0.0 2.3 3 0 0 3 3 3 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) WD40 PF00400.32 KND99450.1 - 4.2e-11 43.2 8.5 0.061 14.2 0.3 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND99450.1 - 4.1e-07 30.2 3.1 0.26 11.6 0.0 6.1 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain ACBP PF00887.19 KND99451.1 - 6.4e-09 35.9 0.2 1.3e-08 34.9 0.2 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Ribosomal_L11_N PF03946.14 KND99454.1 - 9.7e-22 76.6 0.4 2.2e-21 75.4 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KND99454.1 - 8.4e-17 61.4 0.4 2.1e-16 60.2 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Asp PF00026.23 KND99455.1 - 2.3e-61 208.0 0.4 6.7e-50 170.3 0.2 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KND99455.1 - 8.2e-08 32.7 3.5 0.00048 20.4 0.7 2.5 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KND99455.1 - 3.5e-05 24.4 0.0 4.4 8.0 0.0 3.5 3 0 0 3 3 3 3 Aspartyl protease gag-asp_proteas PF13975.6 KND99455.1 - 0.0013 19.2 0.0 5.6 7.6 0.0 3.4 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease RA PF00788.23 KND99456.1 - 3.1e-14 53.4 0.1 6.4e-14 52.4 0.1 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.17 KND99456.1 - 2.7e-08 33.8 0.1 9e-08 32.1 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KND99456.1 - 1.1e-05 25.8 0.0 2.6e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 KND99456.1 - 0.083 13.1 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Metallophos PF00149.28 KND99460.1 - 1.2e-19 71.6 0.1 3.6e-19 70.1 0.1 1.9 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CDC45 PF02724.14 KND99460.1 - 0.0031 15.9 2.2 0.0037 15.6 2.2 1.1 1 0 0 1 1 1 1 CDC45-like protein PIEZO PF15917.5 KND99460.1 - 0.2 11.1 6.6 0.42 10.1 6.6 1.4 1 0 0 1 1 1 0 Piezo DUF4358 PF14270.6 KND99460.1 - 0.83 10.0 7.4 1.7 9.0 6.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) Pkinase PF00069.25 KND99462.1 - 5e-65 219.5 0.0 6.7e-65 219.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND99462.1 - 9.3e-49 166.0 0.0 1.5e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 KND99462.1 - 5.7e-27 94.0 0.0 1.1e-26 93.1 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 KND99462.1 - 6.9e-10 39.2 0.1 1.8e-09 37.9 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KND99462.1 - 2.6e-09 37.0 0.1 9.4e-09 35.3 0.1 2.0 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 KND99462.1 - 4e-05 23.1 0.0 0.019 14.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KND99462.1 - 0.00069 18.5 0.2 0.0017 17.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase SAM_4 PF18017.1 KND99462.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Pkinase PF00069.25 KND99464.1 - 4.4e-36 124.6 0.0 8.3e-22 77.8 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND99464.1 - 8.5e-16 58.0 0.0 5e-12 45.6 0.0 2.9 2 2 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KND99464.1 - 0.00033 20.7 0.0 0.00087 19.3 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KND99464.1 - 0.0032 17.1 0.1 0.021 14.4 0.1 2.1 2 0 0 2 2 2 1 RIO1 family YrbL-PhoP_reg PF10707.9 KND99464.1 - 0.0049 16.4 0.2 0.013 15.0 0.1 1.8 2 1 0 2 2 2 1 PhoP regulatory network protein YrbL Haspin_kinase PF12330.8 KND99464.1 - 0.0086 15.1 0.1 0.016 14.2 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KND99464.1 - 0.055 12.8 0.1 0.055 12.8 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ADH_zinc_N PF00107.26 KND99466.1 - 1.9e-11 44.1 0.0 3.4e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KND99466.1 - 7.7e-10 39.9 0.0 1.4e-09 39.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KND99466.1 - 0.023 14.6 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DFP PF04127.15 KND99466.1 - 0.025 14.4 0.0 0.084 12.7 0.0 1.8 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein CSD PF00313.22 KND99467.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain DUF1373 PF07117.11 KND99467.1 - 0.14 12.2 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) Acetyltransf_1 PF00583.25 KND99469.1 - 1e-14 54.7 0.0 1.2e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KND99469.1 - 5.3e-07 30.0 0.0 6.9e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KND99469.1 - 9.9e-07 28.7 0.0 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KND99469.1 - 0.014 15.4 0.0 0.019 15.1 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KND99469.1 - 0.069 13.3 0.0 0.22 11.6 0.0 1.6 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain IFT57 PF10498.9 KND99469.1 - 0.18 10.8 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 LSM PF01423.22 KND99470.1 - 8.1e-06 25.5 0.1 8.5e-06 25.4 0.1 1.0 1 0 0 1 1 1 1 LSM domain THOC7 PF05615.13 KND99471.1 - 0.018 15.3 2.6 0.032 14.5 2.6 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 Phage_Orf51 PF06194.11 KND99471.1 - 0.018 15.0 0.6 0.049 13.7 0.6 1.6 1 0 0 1 1 1 0 Phage Conserved Open Reading Frame 51 JIP_LZII PF16471.5 KND99471.1 - 0.24 11.6 1.4 0.7 10.1 1.1 2.0 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Clr5 PF14420.6 KND99473.1 - 0.061 13.6 0.2 0.069 13.4 0.2 1.1 1 0 0 1 1 1 0 Clr5 domain Ribosomal_S2 PF00318.20 KND99474.1 - 5.2e-22 78.1 0.2 4.9e-13 48.8 0.0 2.4 2 1 1 3 3 3 2 Ribosomal protein S2 40S_SA_C PF16122.5 KND99474.1 - 1.2e-06 29.8 10.1 2.7e-06 28.6 10.1 1.6 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus MFS_1 PF07690.16 KND99477.1 - 2.5e-09 36.5 36.2 7e-09 35.1 10.2 2.5 3 0 0 3 3 3 2 Major Facilitator Superfamily MFS_1 PF07690.16 KND99480.1 - 1.9e-10 40.2 33.6 2.5e-09 36.5 12.5 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KND99480.1 - 8e-05 21.1 0.1 0.00018 20.0 0.1 1.6 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Gpi1 PF05024.15 KND99481.1 - 1.9e-59 200.9 12.9 1.9e-59 200.9 12.9 1.6 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Zn_clus PF00172.18 KND99482.1 - 5.1e-11 42.5 29.2 9e-06 25.7 8.9 3.4 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldose_epim PF01263.20 KND99487.1 - 2.3e-37 128.9 0.2 2.9e-37 128.6 0.2 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase PAP2_3 PF14378.6 KND99489.1 - 5.3e-22 78.4 12.3 5.3e-22 78.4 12.3 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KND99489.1 - 2.1e-08 34.0 9.5 2.1e-08 34.0 9.5 2.6 2 1 0 2 2 2 1 PAP2 superfamily Ribosomal_S6 PF01250.17 KND99490.1 - 5.2e-25 87.5 0.0 6.2e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 MutS_V PF00488.21 KND99494.1 - 2.3e-76 256.1 0.1 4.3e-76 255.2 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KND99494.1 - 2.6e-33 115.8 2.8 6.9e-33 114.5 2.8 1.8 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 KND99494.1 - 9.8e-17 61.1 1.0 3.5e-16 59.3 1.0 2.0 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 KND99494.1 - 2.7e-09 37.3 0.2 1.9e-08 34.6 0.1 2.3 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 KND99494.1 - 4.1e-07 30.4 2.7 1.3e-06 28.7 0.8 2.8 2 1 0 2 2 2 1 MutS domain II Ceramidase PF05875.12 KND99495.1 - 3.5e-92 308.6 11.7 4.1e-92 308.3 11.7 1.0 1 0 0 1 1 1 1 Ceramidase MotA_ExbB PF01618.16 KND99495.1 - 0.091 12.5 0.1 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family p450 PF00067.22 KND99498.1 - 1.4e-48 165.8 0.0 1.8e-48 165.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M99_m PF17130.4 KND99498.1 - 0.049 13.6 0.0 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 beta-barrel domain of carboxypeptidase M99 PAPS_reduct PF01507.19 KND99499.1 - 2.4e-43 148.2 0.0 3e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DegQ PF08181.11 KND99500.1 - 0.085 13.0 0.2 0.093 12.8 0.2 1.1 1 0 0 1 1 1 0 DegQ (SacQ) family Nas2_N PF18265.1 KND99501.1 - 3.1e-20 71.9 0.1 5.7e-20 71.0 0.1 1.4 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_2 PF13180.6 KND99501.1 - 1.4e-07 31.7 0.2 2.8e-07 30.8 0.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KND99501.1 - 0.00015 22.0 0.0 0.00026 21.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KND99501.1 - 0.00029 20.6 0.1 0.0012 18.7 0.1 2.1 1 1 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KND99501.1 - 0.00053 20.3 0.0 0.00097 19.5 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain ERCC3_RAD25_C PF16203.5 KND99501.1 - 0.088 12.0 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Urm1 PF09138.11 KND99502.1 - 2.1e-33 114.6 0.2 2.3e-33 114.4 0.2 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) DDOST_48kD PF03345.14 KND99504.1 - 4.7e-107 358.4 0.5 9.2e-106 354.1 0.5 2.1 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF1254 PF06863.12 KND99504.1 - 0.018 15.1 0.1 0.034 14.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1254) Prefoldin_2 PF01920.20 KND99505.1 - 6.6e-19 67.8 11.6 8.6e-19 67.5 11.6 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 KND99505.1 - 1.4e-05 25.0 13.2 2.9e-05 24.0 2.1 2.1 2 0 0 2 2 2 2 Prefoldin subunit Sipho_Gp157 PF05565.11 KND99505.1 - 0.0019 18.2 6.3 0.0019 18.2 6.3 1.6 1 1 1 2 2 2 2 Siphovirus Gp157 TPR_MLP1_2 PF07926.12 KND99505.1 - 0.0068 16.5 3.9 0.0068 16.5 3.9 2.1 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein CK2S PF15011.6 KND99505.1 - 0.016 15.1 4.6 0.019 14.9 4.6 1.1 1 0 0 1 1 1 0 Casein Kinase 2 substrate Phage_HK97_TLTM PF06120.11 KND99505.1 - 0.14 11.4 7.5 0.3 10.2 7.5 1.5 1 1 0 1 1 1 0 Tail length tape measure protein PRKG1_interact PF15898.5 KND99505.1 - 0.89 10.5 11.9 2.6 9.0 8.3 2.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain WSD PF15613.6 KND99505.1 - 1.2 9.7 5.0 0.35 11.4 0.6 1.9 2 0 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Peptidase_S46 PF10459.9 KND99505.1 - 1.5 7.3 8.2 1.6 7.2 8.2 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF1664 PF07889.12 KND99505.1 - 4.7 7.3 11.0 4.3 7.4 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Nop25 PF09805.9 KND99505.1 - 5.2 7.5 11.9 11 6.5 3.6 2.0 1 1 1 2 2 2 0 Nucleolar protein 12 (25kDa) LMBR1 PF04791.16 KND99505.1 - 5.4 5.8 5.9 5.9 5.7 5.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein KELK PF15796.5 KND99505.1 - 6.8 7.2 18.6 4.3 7.8 3.5 2.3 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Seryl_tRNA_N PF02403.22 KND99505.1 - 7.4 6.8 13.4 9.3 6.5 4.3 2.1 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Swi5 PF07061.11 KND99505.1 - 7.9 6.6 12.4 4.6 7.4 2.5 2.4 1 1 1 2 2 2 0 Swi5 CorA PF01544.18 KND99505.1 - 9.5 5.4 7.6 6.3 6.0 1.8 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein ARD PF03079.14 KND99506.1 - 6.2e-41 140.2 1.0 7.6e-41 139.9 1.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KND99506.1 - 1.3e-09 37.7 0.0 2.1e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KND99506.1 - 5.6e-06 26.3 0.0 8.3e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KND99506.1 - 7.5e-06 25.6 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.6 KND99506.1 - 0.026 14.2 0.0 0.072 12.8 0.0 1.5 1 1 1 2 2 2 0 Cupin-like domain Cupin_3 PF05899.12 KND99506.1 - 0.041 13.6 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_6 PF12852.7 KND99506.1 - 0.12 12.1 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Cupin Kri1 PF05178.12 KND99506.1 - 0.2 12.2 5.6 0.38 11.3 5.5 1.6 1 1 0 1 1 1 0 KRI1-like family WD40 PF00400.32 KND99508.1 - 6.4e-30 102.8 11.4 1.8e-06 28.6 0.6 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND99508.1 - 3.9e-12 46.3 1.0 0.28 11.5 0.0 5.7 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KND99508.1 - 6.6e-05 22.9 0.9 0.1 12.5 0.1 2.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KND99508.1 - 0.001 18.5 0.0 0.23 10.7 0.0 2.2 1 1 1 2 2 2 2 WD40-like domain 6PF2K PF01591.18 KND99510.1 - 3.6e-45 154.0 4.2 4.8e-45 153.6 4.2 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.6 KND99510.1 - 1.8e-12 47.7 0.1 2.7e-12 47.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KND99510.1 - 4.9e-08 32.7 0.1 1.1e-07 31.6 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.6 KND99510.1 - 4.4e-06 27.1 0.0 7.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KND99510.1 - 1.3e-05 25.7 0.0 0.00011 22.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 KND99510.1 - 3.6e-05 23.7 0.0 7.9e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.6 KND99510.1 - 0.00031 21.0 0.0 0.00079 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KND99510.1 - 0.00099 18.9 0.2 0.0014 18.4 0.2 1.2 1 0 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 KND99510.1 - 0.0019 18.0 0.1 0.0048 16.7 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 KND99510.1 - 0.0071 15.9 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 KND99510.1 - 0.0088 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin SRP54 PF00448.22 KND99510.1 - 0.012 15.3 0.1 0.037 13.7 0.1 1.9 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KND99510.1 - 0.015 15.7 0.0 0.029 14.8 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 KND99510.1 - 0.024 14.9 0.0 0.056 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KND99510.1 - 0.026 15.0 0.1 0.038 14.5 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 KND99510.1 - 0.042 13.4 0.0 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KND99510.1 - 0.047 14.1 0.6 1.3 9.4 0.6 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KND99510.1 - 0.049 13.7 0.4 0.26 11.4 0.0 2.4 3 0 0 3 3 2 0 50S ribosome-binding GTPase RB_A PF01858.17 KND99510.1 - 0.08 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Retinoblastoma-associated protein A domain NTPase_1 PF03266.15 KND99510.1 - 0.085 12.8 0.0 0.15 12.0 0.0 1.6 1 1 0 1 1 1 0 NTPase AAA_5 PF07728.14 KND99510.1 - 0.099 12.6 0.0 3.3 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 KND99510.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Pet127 PF08634.10 KND99511.1 - 1.6e-104 349.2 0.6 2.6e-104 348.5 0.6 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 QSregVF PF13652.6 KND99511.1 - 0.058 13.4 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor IL15 PF02372.15 KND99511.1 - 0.098 12.7 0.2 0.25 11.3 0.2 1.7 1 0 0 1 1 1 0 Interleukin 15 Hap4_Hap_bind PF10297.9 KND99512.1 - 2.4e-08 33.8 7.1 5e-08 32.8 7.1 1.6 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 KND99512.1 - 2.1e-05 24.5 14.6 0.0033 17.5 11.4 2.6 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 KND99512.1 - 0.0036 17.4 16.8 0.15 12.2 11.2 2.7 1 1 1 2 2 2 2 Basic region leucine zipper FliD_N PF02465.18 KND99512.1 - 0.11 13.2 6.2 1.8 9.3 6.2 2.9 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus NIF PF03031.18 KND99514.1 - 1.5e-41 141.7 0.1 2.5e-41 141.1 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase CDP-OH_P_transf PF01066.21 KND99516.1 - 6.4e-12 46.1 0.5 6.4e-12 46.1 0.5 1.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PH PF00169.29 KND99518.1 - 0.0001 22.8 3.9 0.0004 20.9 3.9 2.1 1 1 0 1 1 1 1 PH domain HTH_AsnC-type PF13404.6 KND99522.1 - 0.12 12.2 0.2 0.25 11.2 0.2 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain DNA_binding_1 PF01035.20 KND99523.1 - 1.7e-23 82.5 0.1 3.4e-23 81.5 0.1 1.5 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF3545 PF12065.8 KND99523.1 - 0.069 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) AA_permease PF00324.21 KND99524.1 - 3.9e-144 480.8 38.3 4.4e-144 480.6 38.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND99524.1 - 8.5e-43 146.7 39.7 1e-42 146.5 39.7 1.1 1 0 0 1 1 1 1 Amino acid permease CTNNBL PF08216.11 KND99524.1 - 0.17 12.0 0.5 0.41 10.8 0.0 1.7 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear PCI PF01399.27 KND99525.1 - 1.2e-05 25.7 1.8 2.6e-05 24.7 0.3 2.4 3 0 0 3 3 3 1 PCI domain Glyco_hydro_98C PF08307.11 KND99525.1 - 0.048 13.1 0.4 0.099 12.1 0.4 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 C-terminal domain Asp PF00026.23 KND99527.1 - 1.3e-51 176.0 1.1 1.5e-51 175.8 1.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KND99527.1 - 0.0075 16.5 1.6 0.13 12.5 0.4 2.2 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KND99527.1 - 0.0097 15.7 0.1 0.11 12.2 0.0 2.1 1 1 1 2 2 2 1 Xylanase inhibitor C-terminal V-ATPase_C PF03223.15 KND99529.1 - 4.3e-113 378.5 4.9 4.9e-113 378.3 4.9 1.0 1 0 0 1 1 1 1 V-ATPase subunit C SURF6 PF04935.12 KND99530.1 - 1.2e-44 152.5 49.9 1.2e-44 152.5 49.9 2.2 2 0 0 2 2 2 1 Surfeit locus protein 6 TB2_DP1_HVA22 PF03134.19 KND99531.1 - 1.9e-26 91.8 3.4 2.9e-26 91.2 3.4 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Git3 PF11710.8 KND99531.1 - 0.085 12.6 8.5 0.13 12.0 8.3 1.5 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Adaptin_N PF01602.20 KND99532.1 - 8.2e-120 400.8 9.0 9.9e-120 400.5 9.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KND99532.1 - 2.5e-17 63.2 0.2 5.5e-17 62.1 0.2 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KND99532.1 - 0.0087 16.1 6.4 0.029 14.4 0.1 3.5 3 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Nudc_N PF14050.6 KND99532.1 - 0.071 13.1 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 N-terminal conserved domain of Nudc. Pro_isomerase PF00160.21 KND99533.1 - 3.9e-19 69.5 0.1 3.9e-19 69.5 0.1 1.7 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.25 KND99534.1 - 4.9e-43 147.4 0.0 9e-43 146.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND99534.1 - 6.3e-14 51.9 0.0 4.5e-13 49.1 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KND99534.1 - 0.031 13.6 0.3 0.099 11.9 0.0 1.9 2 0 0 2 2 2 0 Kinase-like AGA2 PF17366.2 KND99534.1 - 0.097 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 A-agglutinin-binding subunit Aga2 Ribosomal_S14 PF00253.21 KND99536.1 - 5.9e-19 67.6 0.0 3.7e-17 61.8 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein S14p/S29e Baculo_p74_N PF08404.10 KND99536.1 - 0.029 13.5 0.0 0.037 13.1 0.0 1.1 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal ADH_N_2 PF16884.5 KND99537.1 - 6.8e-23 80.6 0.0 1.3e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KND99537.1 - 5.9e-20 71.6 0.0 9.6e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KND99537.1 - 1.7e-06 29.1 0.0 3.5e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 KND99537.1 - 0.059 13.1 0.1 6 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2855) Ost5 PF05251.12 KND99537.1 - 0.15 12.4 0.2 0.26 11.6 0.2 1.3 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit 5 AMP-binding PF00501.28 KND99539.1 - 1.1e-51 175.7 0.0 1.5e-28 99.6 0.0 2.8 2 1 0 2 2 2 2 AMP-binding enzyme Nup_retrotrp_bd PF10599.9 KND99540.1 - 0.00053 20.6 8.2 0.00053 20.6 8.2 9.5 3 2 3 6 6 6 2 Retro-transposon transporting motif CRAL_TRIO PF00650.20 KND99541.1 - 3.2e-35 121.2 0.0 5.1e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KND99541.1 - 5.4e-06 26.6 0.0 1.1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KND99541.1 - 1.5e-05 25.1 0.0 4.6e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain PHD PF00628.29 KND99542.1 - 1.3e-08 34.5 2.5 1.3e-08 34.5 2.5 1.8 2 0 0 2 2 2 1 PHD-finger DUF1033 PF06279.11 KND99542.1 - 0.04 14.1 0.0 0.09 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) PHD_2 PF13831.6 KND99542.1 - 0.23 11.1 4.1 0.37 10.4 4.1 1.4 1 0 0 1 1 1 0 PHD-finger Sec1 PF00995.23 KND99543.1 - 9.5e-107 358.6 24.2 1.1e-106 358.4 24.2 1.0 1 0 0 1 1 1 1 Sec1 family Syntaxin-18_N PF10496.9 KND99543.1 - 0.78 10.0 4.7 0.63 10.3 1.9 2.4 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Peptidase_M16_M PF16187.5 KND99545.1 - 2.6e-78 263.1 0.9 2.6e-78 263.1 0.9 1.6 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KND99545.1 - 2.1e-42 144.6 0.3 2.3e-41 141.2 0.0 2.6 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KND99545.1 - 9.7e-26 90.9 1.5 2.3e-14 53.8 0.0 3.7 4 0 0 4 4 4 2 Peptidase M16 inactive domain HNHc_6 PF16784.5 KND99545.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative HNHc nuclease Rogdi_lz PF10259.9 KND99546.1 - 2.4e-65 220.7 3.1 2.8e-65 220.4 3.1 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein HSP9_HSP12 PF04119.12 KND99546.1 - 0.023 15.1 0.4 0.052 13.9 0.4 1.6 1 0 0 1 1 1 0 Heat shock protein 9/12 SUIM_assoc PF16619.5 KND99547.1 - 0.1 12.7 0.0 0.1 12.7 0.0 4.9 3 2 1 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 KND99547.1 - 1.5 9.1 9.6 0.74 10.1 1.9 2.6 2 1 1 3 3 3 0 Anti-sigma-K factor rskA DUF898 PF05987.13 KND99548.1 - 0.013 14.5 0.3 0.02 13.9 0.3 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) LRR_2 PF07723.13 KND99548.1 - 0.97 10.2 4.9 0.85 10.4 0.1 3.1 3 0 0 3 3 3 0 Leucine Rich Repeat CFEM PF05730.11 KND99549.1 - 2.1e-10 40.6 12.4 4.1e-10 39.6 12.4 1.5 1 0 0 1 1 1 1 CFEM domain Pol_alpha_B_N PF08418.10 KND99549.1 - 0.2 11.6 8.8 0.25 11.3 8.8 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal SOG2 PF10428.9 KND99549.1 - 0.36 10.0 23.5 0.42 9.8 23.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Utp14 PF04615.13 KND99549.1 - 1.9 7.0 9.6 2.2 6.7 9.6 1.0 1 0 0 1 1 1 0 Utp14 protein Hamartin PF04388.12 KND99549.1 - 2.9 6.4 14.5 3.3 6.3 14.5 1.1 1 0 0 1 1 1 0 Hamartin protein Plasmodium_Vir PF05795.11 KND99549.1 - 6 6.2 9.5 8.2 5.7 9.5 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ndc1_Nup PF09531.10 KND99549.1 - 9 4.8 12.0 10 4.7 12.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup QWRF PF04484.12 KND99549.1 - 9.4 5.9 19.0 12 5.5 19.0 1.3 1 0 0 1 1 1 0 QWRF family Amidohydro_1 PF01979.20 KND99551.1 - 6.7e-72 242.7 0.0 8e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KND99551.1 - 4e-10 39.8 0.1 7.8e-07 28.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KND99551.1 - 0.00026 20.4 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase zf-RRPl_C4 PF17026.5 KND99551.1 - 0.0028 17.8 0.5 0.0054 16.8 0.5 1.4 1 0 0 1 1 1 1 Putative ribonucleoprotein zinc-finger pf C4 type SKG6 PF08693.10 KND99554.1 - 0.00069 19.0 0.4 0.0013 18.1 0.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KND99554.1 - 0.058 13.2 1.5 0.06 13.1 0.1 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4448) ACC_central PF08326.12 KND99554.1 - 0.064 11.5 0.2 0.08 11.1 0.2 1.0 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region PAP2 PF01569.21 KND99555.1 - 9.1e-24 83.8 1.4 9.1e-24 83.8 1.4 2.2 1 1 2 3 3 3 1 PAP2 superfamily DUF2834 PF11196.8 KND99555.1 - 0.46 10.9 10.9 0.27 11.6 2.3 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF2834) PAP2_C PF14360.6 KND99555.1 - 8.5 7.0 13.1 2.5 8.7 4.0 3.3 3 1 0 3 3 3 0 PAP2 superfamily C-terminal PSP1 PF04468.12 KND99556.1 - 5e-28 97.2 1.6 5e-28 97.2 1.6 1.9 2 0 0 2 2 2 1 PSP1 C-terminal conserved region DUF4131 PF13567.6 KND99557.1 - 0.021 14.5 1.9 0.023 14.4 1.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Rad60-SLD PF11976.8 KND99558.1 - 1.6e-18 66.3 0.0 1.9e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KND99558.1 - 7.9e-10 38.3 0.0 9.2e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Vasohibin PF14822.6 KND99558.1 - 0.12 11.5 0.1 0.15 11.3 0.1 1.1 1 0 0 1 1 1 0 Vasohibin DUF948 PF06103.11 KND99559.1 - 0.016 15.4 0.5 0.016 15.4 0.5 4.1 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) TarH PF02203.15 KND99559.1 - 0.034 14.1 2.2 0.054 13.4 0.6 2.1 2 0 0 2 2 2 0 Tar ligand binding domain homologue NPV_P10 PF05531.12 KND99559.1 - 0.13 12.8 4.6 1.1 9.7 0.2 3.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein SesA PF17107.5 KND99559.1 - 0.26 11.5 2.8 13 6.0 0.1 3.1 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Baculo_PEP_C PF04513.12 KND99559.1 - 0.98 9.5 23.4 3 7.9 5.6 4.1 3 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus MgsA_C PF12002.8 KND99560.1 - 1.4e-54 184.5 0.0 2.8e-54 183.6 0.0 1.5 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KND99560.1 - 5.7e-20 71.4 0.0 1.9e-19 69.8 0.0 2.0 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KND99560.1 - 9.5e-18 64.9 0.0 2.1e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KND99560.1 - 7.9e-15 55.0 0.0 1.4e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KND99560.1 - 1.1e-08 35.0 0.0 2.6e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.6 KND99560.1 - 6.3e-08 32.7 0.0 2.2e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KND99560.1 - 2.5e-07 30.8 0.1 1.6e-06 28.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KND99560.1 - 6.4e-07 29.6 0.0 1.6e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 KND99560.1 - 7.3e-05 22.2 0.1 0.02 14.3 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KND99560.1 - 0.00022 21.7 4.7 0.034 14.5 0.1 3.1 2 1 1 3 3 3 2 AAA ATPase domain AAA_3 PF07726.11 KND99560.1 - 0.0016 18.3 0.0 0.0067 16.3 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KND99560.1 - 0.0052 16.6 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 KND99560.1 - 0.0082 16.7 0.2 0.055 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 KND99560.1 - 0.01 16.0 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KND99560.1 - 0.027 14.2 0.0 0.058 13.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_8 PF12780.7 KND99560.1 - 0.12 11.7 0.0 0.35 10.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 AAA_22 PF13401.6 KND99560.1 - 0.36 11.1 6.2 2.4 8.5 0.6 3.3 3 1 0 3 3 2 0 AAA domain ResIII PF04851.15 KND99560.1 - 0.48 10.4 2.2 1.7 8.6 0.1 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_17 PF13207.6 KND99560.1 - 0.64 10.4 4.3 1.3 9.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain OGG_N PF07934.12 KND99563.1 - 5.3e-30 104.0 0.1 1e-29 103.1 0.1 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KND99563.1 - 6.9e-18 65.1 0.0 1.3e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KND99563.1 - 0.0016 18.2 0.0 0.0041 16.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif LCD1 PF09798.9 KND99566.1 - 1.3e-147 493.0 15.8 1.5e-147 492.8 15.8 1.0 1 0 0 1 1 1 1 DNA damage checkpoint protein PAS_3 PF08447.12 KND99566.1 - 0.016 15.5 0.0 0.058 13.7 0.0 2.0 2 0 0 2 2 2 0 PAS fold TMF_TATA_bd PF12325.8 KND99566.1 - 0.048 13.9 5.6 3.7 7.8 2.4 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 KND99566.1 - 0.1 13.1 4.2 0.21 12.0 4.2 1.5 1 0 0 1 1 1 0 Fez1 HIP1_clath_bdg PF16515.5 KND99566.1 - 2.2 8.9 8.8 3.3 8.4 5.9 2.6 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DivIC PF04977.15 KND99566.1 - 2.9 7.7 4.9 3.6 7.4 1.0 2.5 1 1 1 2 2 2 0 Septum formation initiator EMG1 PF03587.14 KND99567.1 - 4.5e-79 264.6 0.0 5.4e-79 264.4 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase RP854 PF17460.2 KND99567.1 - 0.19 11.4 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein RP854 Cyclin_C_2 PF16899.5 KND99568.1 - 7.9e-29 100.1 0.2 4.6e-26 91.2 0.0 2.5 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 KND99568.1 - 4.9e-12 45.7 0.5 9.2e-12 44.8 0.5 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 KND99568.1 - 0.012 15.6 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat DUF326 PF03860.16 KND99568.1 - 2 8.5 4.2 2 8.5 0.9 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF326) Pkinase PF00069.25 KND99569.1 - 3.6e-72 242.9 0.0 6.3e-72 242.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND99569.1 - 4.9e-36 124.3 0.0 7.9e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 KND99569.1 - 5e-31 106.9 0.6 1.1e-30 105.8 0.6 1.6 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Kinase-like PF14531.6 KND99569.1 - 0.00012 21.5 0.0 0.00025 20.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KND99569.1 - 0.11 12.4 2.4 0.12 12.3 0.1 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family Prenyltransf PF01255.19 KND99572.1 - 8e-73 244.7 0.0 1.1e-72 244.2 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase SHP PF03579.13 KND99572.1 - 0.2 11.6 0.4 0.44 10.5 0.4 1.5 1 0 0 1 1 1 0 Small hydrophobic protein HisG PF01634.18 KND99573.1 - 4e-38 130.9 0.0 5.6e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KND99573.1 - 9.5e-28 96.2 0.0 1.5e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 KND99573.1 - 0.0089 16.0 0.1 0.016 15.1 0.1 1.4 1 1 0 1 1 1 1 NMT1/THI5 like PCI PF01399.27 KND99574.1 - 6.3e-15 55.6 0.7 2.8e-14 53.5 0.7 2.2 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 KND99574.1 - 2.2e-13 50.0 2.9 2.2e-13 50.0 2.9 2.5 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN5 C-terminal domain DS PF01916.17 KND99574.1 - 0.071 12.4 0.4 0.17 11.1 0.2 1.7 1 1 0 1 1 1 0 Deoxyhypusine synthase Glyco_hydro_72 PF03198.14 KND99575.1 - 4.7e-133 443.3 5.2 6.1e-133 442.9 5.2 1.1 1 0 0 1 1 1 1 Glucanosyltransferase TraG-D_C PF12696.7 KND99575.1 - 0.026 14.5 3.9 0.05 13.6 3.9 1.4 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG T4SS-DNA_transf PF02534.14 KND99575.1 - 0.071 11.9 1.1 0.12 11.2 1.1 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Adap_comp_sub PF00928.21 KND99577.1 - 7.5e-87 291.0 0.9 1.1e-86 290.6 0.9 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KND99577.1 - 5.8e-08 32.8 3.5 8.8e-08 32.2 2.9 1.7 1 1 1 2 2 2 1 Clathrin adaptor complex small chain DUF2458 PF10454.9 KND99578.1 - 1.2e-06 28.3 2.3 1.9e-06 27.6 0.9 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2458) E3_UbLigase_R4 PF13764.6 KND99578.1 - 0.0016 16.7 2.2 0.0018 16.5 2.2 1.1 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase UBR4 Globin PF00042.22 KND99578.1 - 0.023 15.3 0.3 13 6.4 0.0 2.6 2 1 0 2 2 2 0 Globin Pescadillo_N PF06732.11 KND99578.1 - 0.082 12.4 5.5 0.95 9.0 1.8 2.2 2 0 0 2 2 2 0 Pescadillo N-terminus Selenoprotein_S PF06936.11 KND99578.1 - 0.094 12.5 1.7 0.15 11.9 1.7 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) CorA PF01544.18 KND99578.1 - 0.74 9.1 6.3 1.1 8.6 6.3 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein RFX_DNA_binding PF02257.15 KND99579.1 - 4.4e-13 49.7 0.2 1.1e-12 48.4 0.2 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain Phage_glycop_gL PF11108.8 KND99579.1 - 0.092 12.8 0.0 0.4 10.8 0.0 2.1 1 0 0 1 1 1 0 Viral glycoprotein L PCNA_N PF00705.18 KND99580.1 - 1.3e-48 163.9 6.5 5.7e-48 161.8 2.9 2.7 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KND99580.1 - 1.1e-46 158.1 0.0 2.2e-46 157.2 0.0 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 KND99580.1 - 5.7e-06 25.6 1.0 0.0002 20.5 0.3 2.0 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 KND99580.1 - 4.8e-05 22.9 0.2 5.8e-05 22.7 0.2 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 KND99580.1 - 0.0011 18.2 0.0 0.094 11.8 0.0 2.1 2 0 0 2 2 2 2 Hus1-like protein Phyto-Amp PF15438.6 KND99580.1 - 0.031 14.1 0.2 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 Antigenic membrane protein of phytoplasma RVT_2 PF07727.14 KND99580.1 - 0.055 13.1 0.3 0.16 11.6 0.1 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF229 PF02995.17 KND99580.1 - 0.087 11.4 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) PCNA_N PF00705.18 KND99581.1 - 2.8e-29 101.4 1.0 3.1e-29 101.3 1.0 1.0 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Oxysterol_BP PF01237.18 KND99582.1 - 7e-104 347.6 0.5 1.9e-103 346.2 0.5 1.8 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KND99582.1 - 1.5e-35 121.3 0.7 3.9e-35 120.0 0.7 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain EMP24_GP25L PF01105.24 KND99582.1 - 0.0057 16.6 1.4 0.13 12.2 0.1 2.8 3 0 0 3 3 3 1 emp24/gp25L/p24 family/GOLD PH PF00169.29 KND99582.1 - 0.011 16.3 0.3 0.048 14.2 0.3 2.2 1 0 0 1 1 1 0 PH domain zf-RING_UBOX PF13445.6 KND99583.1 - 2.4e-09 37.1 8.9 7.7e-09 35.4 8.9 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KND99583.1 - 3.7e-07 29.9 8.3 3.7e-07 29.9 8.3 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KND99583.1 - 1.9e-06 27.6 6.8 1.9e-06 27.6 6.8 3.1 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KND99583.1 - 4.8e-06 26.8 6.9 4.8e-06 26.8 6.9 3.8 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KND99583.1 - 8.5e-06 25.8 8.4 8.5e-06 25.8 8.4 2.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KND99583.1 - 1e-05 25.4 6.8 1e-05 25.4 6.8 2.7 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KND99583.1 - 0.00018 21.3 5.1 0.00018 21.3 5.1 3.0 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KND99583.1 - 0.0003 20.5 3.9 0.0003 20.5 3.9 2.6 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Csm1_N PF18504.1 KND99583.1 - 0.008 16.5 0.3 0.049 14.0 0.1 2.3 2 0 0 2 2 2 1 Csm1 N-terminal domain Sina PF03145.16 KND99583.1 - 0.07 13.1 14.4 0.38 10.7 5.3 2.6 1 1 0 2 2 2 0 Seven in absentia protein family Shugoshin_N PF07558.11 KND99583.1 - 0.38 10.7 3.8 4.1 7.3 0.2 2.7 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region zf-TRAF PF02176.18 KND99583.1 - 1.7 9.4 31.7 0.84 10.4 6.8 4.3 2 1 2 4 4 3 0 TRAF-type zinc finger MAGE PF01454.19 KND99584.1 - 5.7e-14 52.3 0.8 1e-12 48.2 0.8 2.1 1 1 0 1 1 1 1 MAGE family FTA2 PF13095.6 KND99584.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 FAD_binding_1 PF00667.20 KND99585.1 - 2.2e-69 233.4 0.0 3.4e-69 232.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KND99585.1 - 5.1e-34 117.5 1.1 1.2e-33 116.4 1.1 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KND99585.1 - 4.6e-19 69.1 0.1 1.3e-18 67.6 0.0 1.9 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Ins_P5_2-kin PF06090.12 KND99586.1 - 3.9e-27 95.6 0.0 5.2e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase AIM24 PF01987.17 KND99587.1 - 3.6e-08 33.4 0.0 5.6e-08 32.8 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial biogenesis AIM24 MKT1_C PF12246.8 KND99588.1 - 3.8e-35 121.3 0.4 1.1e-34 119.8 0.1 1.9 3 0 0 3 3 3 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KND99588.1 - 4.5e-23 81.4 0.0 1.3e-22 80.0 0.0 1.9 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 KND99588.1 - 4.4e-12 46.4 0.0 3.5e-10 40.2 0.0 2.7 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 KND99588.1 - 0.00017 21.9 0.0 0.00063 20.0 0.0 2.0 1 1 0 1 1 1 1 XPG I-region DUF5010 PF16402.5 KND99588.1 - 0.039 12.8 0.0 0.064 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) UbiA PF01040.18 KND99590.1 - 1e-48 165.9 10.5 1.8e-48 165.1 10.5 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family JAB PF01398.21 KND99591.1 - 5.4e-32 110.2 0.0 9.7e-32 109.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KND99591.1 - 5.5e-30 104.1 0.2 9.7e-30 103.3 0.2 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.13 KND99591.1 - 0.087 12.9 0.0 0.28 11.2 0.0 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF2999 PF11212.8 KND99591.1 - 0.093 13.0 0.0 0.33 11.2 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) ATP_bind_1 PF03029.17 KND99592.1 - 1.1e-67 228.4 0.0 1.3e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 KND99592.1 - 0.00012 21.9 0.0 0.00039 20.3 0.0 1.8 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MipZ PF09140.11 KND99592.1 - 0.00049 19.5 0.0 0.00082 18.7 0.0 1.4 1 0 0 1 1 1 1 ATPase MipZ AAA_10 PF12846.7 KND99592.1 - 0.00059 18.9 0.0 0.00087 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_33 PF13671.6 KND99592.1 - 0.00068 19.8 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KND99592.1 - 0.0019 17.2 0.0 0.0031 16.6 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 KND99592.1 - 0.0025 17.4 0.0 0.011 15.3 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_31 PF13614.6 KND99592.1 - 0.0065 16.4 0.0 0.77 9.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 KND99592.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 KND99592.1 - 0.025 15.1 0.6 0.11 13.0 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KND99592.1 - 0.053 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 KND99592.1 - 0.074 13.0 0.0 0.29 11.1 0.0 2.0 1 1 0 1 1 1 0 NTPase AAA_30 PF13604.6 KND99592.1 - 0.076 12.7 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KND99592.1 - 0.083 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 IstB_IS21 PF01695.17 KND99592.1 - 0.094 12.4 0.3 19 4.9 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein PPV_E1_C PF00519.17 KND99592.1 - 0.097 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase MMR_HSR1 PF01926.23 KND99592.1 - 0.099 12.7 0.0 0.52 10.4 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 KND99592.1 - 0.15 12.4 0.0 0.39 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Prefoldin PF02996.17 KND99593.1 - 0.011 15.7 0.0 0.067 13.1 0.0 2.5 1 1 0 1 1 1 0 Prefoldin subunit Thioredox_DsbH PF03190.15 KND99594.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF255 AA_permease PF00324.21 KND99595.1 - 4.9e-118 394.8 36.6 6e-118 394.5 36.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND99595.1 - 5.8e-31 107.8 37.3 7.3e-31 107.4 37.3 1.1 1 0 0 1 1 1 1 Amino acid permease EMC3_TMCO1 PF01956.16 KND99595.1 - 0.14 11.9 2.7 1.1 8.9 0.0 3.0 2 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Hyphal_reg_CWP PF11765.8 KND99597.1 - 7.8e-72 242.0 10.3 1.9e-71 240.7 10.3 1.7 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Hyr1 PF15789.5 KND99597.1 - 4.4e-41 138.1 445.3 6.2e-06 25.6 15.7 22.2 19 1 1 20 20 20 18 Hyphally regulated cell wall GPI-anchored protein 1 Imm53 PF15580.6 KND99597.1 - 0.00016 21.3 20.7 1.2e+02 2.4 0.0 12.8 16 0 0 16 16 16 0 Immunity protein 53 TFR_dimer PF04253.15 KND99598.1 - 3.3e-22 78.9 1.2 6.8e-22 77.8 0.3 1.9 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KND99598.1 - 1.5e-19 70.5 0.0 2.6e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KND99598.1 - 5.1e-10 39.2 0.0 1.9e-09 37.4 0.0 1.9 1 0 0 1 1 1 1 PA domain DUF1411 PF07199.11 KND99598.1 - 0.19 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) Aldedh PF00171.22 KND99599.1 - 9.4e-176 584.8 0.9 1.1e-175 584.7 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Asp PF00026.23 KND99601.1 - 2.3e-60 204.7 0.2 2.7e-60 204.4 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KND99601.1 - 1.3e-11 45.0 0.7 5.6e-06 26.7 0.2 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Sfi1_C PF10638.9 KND99601.1 - 0.034 14.9 0.1 0.08 13.7 0.1 1.5 2 0 0 2 2 2 0 Spindle body associated protein C-terminus FMN_dh PF01070.18 KND99602.1 - 6.4e-118 393.8 0.0 7.4e-118 393.5 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KND99602.1 - 1.3e-07 31.0 0.1 5.2e-07 29.0 0.0 2.0 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KND99602.1 - 5.1e-06 26.1 0.0 6.7e-05 22.5 0.0 2.4 2 1 0 3 3 3 1 Histidine biosynthesis protein Glu_synthase PF01645.17 KND99602.1 - 5.5e-05 22.5 0.0 0.00013 21.3 0.0 1.6 1 1 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KND99602.1 - 5.5e-05 22.7 0.6 8.8e-05 22.0 0.6 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KND99602.1 - 0.00022 20.6 0.6 0.24 10.7 0.0 2.4 1 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Aa_trans PF01490.18 KND99604.1 - 8.8e-25 87.2 35.0 6.6e-24 84.4 29.4 2.1 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KND99604.1 - 0.045 12.8 30.0 0.13 11.3 27.5 2.4 1 1 1 2 2 2 0 Tryptophan/tyrosine permease family ELMO_CED12 PF04727.13 KND99604.1 - 0.062 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 ELMO/CED-12 family Aa_trans PF01490.18 KND99605.1 - 5.3e-21 74.8 41.7 1.4e-19 70.1 41.7 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KND99605.1 - 8.9e-05 21.7 17.0 8.9e-05 21.7 17.0 3.3 1 1 1 3 3 3 2 Tryptophan/tyrosine permease family NAD_binding_10 PF13460.6 KND99606.1 - 2e-10 40.9 0.1 3.1e-10 40.2 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KND99606.1 - 2.3e-09 37.2 0.0 1.2e-08 34.9 0.1 1.8 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 KND99606.1 - 2.2e-07 30.6 0.0 8.5e-06 25.4 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KND99606.1 - 0.00087 19.7 0.1 0.0015 18.9 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KND99606.1 - 0.0061 16.7 0.1 0.012 15.8 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 KND99606.1 - 0.0063 15.6 0.0 0.067 12.3 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KND99606.1 - 0.0067 15.5 0.0 0.1 11.6 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family YjeF_N PF03853.15 KND99606.1 - 0.011 15.7 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus adh_short PF00106.25 KND99606.1 - 0.02 14.4 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Ldh_1_N PF00056.23 KND99606.1 - 0.071 13.2 0.4 0.15 12.2 0.4 1.7 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KND99606.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KND99606.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Fungal_trans PF04082.18 KND99607.1 - 3.6e-26 91.8 1.0 6.5e-26 90.9 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DHDPS PF00701.22 KND99608.1 - 3.3e-59 200.0 0.0 3.7e-59 199.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.6 KND99608.1 - 2.3e-05 24.0 0.0 3.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase PC4 PF02229.16 KND99608.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) Aa_trans PF01490.18 KND99610.1 - 1.6e-27 96.3 29.6 2.1e-27 95.9 29.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KND99610.1 - 0.00021 20.4 19.3 0.00021 20.4 19.3 2.3 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family MFS_1 PF07690.16 KND99612.1 - 1.2e-15 57.3 39.8 5.8e-09 35.3 24.7 2.8 2 1 2 4 4 4 3 Major Facilitator Superfamily TRI12 PF06609.13 KND99612.1 - 8.6e-05 21.1 23.2 0.002 16.7 6.0 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Conotoxin PF02950.17 KND99612.1 - 0.23 12.5 2.2 0.42 11.7 0.1 2.5 3 0 0 3 3 3 0 Conotoxin EphA2_TM PF14575.6 KND99612.1 - 0.54 11.2 3.2 56 4.7 0.0 3.9 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain DUF1418 PF07214.12 KND99612.1 - 4.8 7.1 7.8 3.3 7.6 1.5 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) TP_methylase PF00590.20 KND99613.1 - 1.3e-24 87.4 0.1 1.9e-24 86.8 0.1 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Per1 PF04080.13 KND99614.1 - 3.8e-85 285.7 13.9 3.8e-85 285.7 13.9 1.6 2 0 0 2 2 2 1 Per1-like family Kelch_2 PF07646.15 KND99614.1 - 0.37 10.9 1.7 0.91 9.6 1.7 1.7 1 0 0 1 1 1 0 Kelch motif Aldolase_II PF00596.21 KND99615.1 - 2.3e-48 164.6 0.1 2.9e-48 164.3 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Asp PF00026.23 KND99617.1 - 4.8e-64 216.7 7.1 6.3e-64 216.4 7.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KND99617.1 - 5.6e-07 30.0 1.2 0.0017 18.6 1.2 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal MFS_1 PF07690.16 KND99618.1 - 8.6e-18 64.4 36.3 2.7e-12 46.3 20.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND99618.1 - 5.8e-05 22.1 9.1 5.8e-05 22.1 9.1 3.3 1 1 0 3 3 3 1 Sugar (and other) transporter ARL6IP6 PF15062.6 KND99618.1 - 0.11 12.7 0.3 8 6.7 0.0 3.0 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix Inhibitor_I24 PF10465.9 KND99619.1 - 0.055 13.5 0.0 0.073 13.1 0.0 1.1 1 0 0 1 1 1 0 PinA peptidase inhibitor FIT1_2 PF17357.2 KND99619.1 - 0.43 10.7 16.7 0.68 10.1 0.7 2.3 1 1 1 2 2 2 0 Facilitor Of iron transport 1 and 2 Ferric_reduct PF01794.19 KND99621.1 - 2.9e-16 59.7 13.6 7.7e-16 58.4 10.0 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KND99621.1 - 6.4e-11 42.6 0.0 1.9e-10 41.1 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KND99621.1 - 1.2e-08 35.0 2.5 1.3e-08 34.9 0.1 2.3 3 0 0 3 3 3 1 FAD-binding domain FIT1_2 PF17357.2 KND99622.1 - 0.011 15.9 37.2 0.016 15.3 20.1 2.3 1 1 1 2 2 2 0 Facilitor Of iron transport 1 and 2 DUF4367 PF14285.6 KND99622.1 - 0.33 11.4 2.5 0.49 10.8 2.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4367) PTCB-BRCT PF12738.7 KND99622.1 - 1.7 8.6 5.9 0.54 10.3 0.7 2.5 1 1 1 2 2 2 0 twin BRCT domain Arrestin_N PF00339.29 KND99623.1 - 1.4e-14 54.4 1.9 8.9e-14 51.8 1.9 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Vps26 PF03643.15 KND99623.1 - 0.009 15.0 0.0 0.018 14.1 0.0 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 KND99623.1 - 0.042 14.3 0.8 4.4 7.8 0.1 2.6 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain polyprenyl_synt PF00348.17 KND99624.1 - 1.7e-49 168.2 0.0 2.1e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Rhabdo_ncap PF00945.18 KND99624.1 - 0.1 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DER1 PF04511.15 KND99625.1 - 3.7e-08 33.5 12.5 6e-08 32.8 9.6 2.3 1 1 1 2 2 2 1 Der1-like family VPS9 PF02204.18 KND99627.1 - 4e-14 52.7 1.7 4.5e-08 33.2 0.2 4.0 3 1 0 3 3 3 2 Vacuolar sorting protein 9 (VPS9) domain DUF87 PF01935.17 KND99628.1 - 0.001 19.2 0.3 0.0022 18.1 0.3 1.6 1 1 0 1 1 1 1 Helicase HerA, central domain SH2_2 PF14633.6 KND99629.1 - 1e-74 250.6 1.2 3.1e-74 249.0 1.2 1.9 1 0 0 1 1 1 1 SH2 domain HTH_44 PF14641.6 KND99629.1 - 1e-36 125.8 1.1 1e-36 125.8 1.1 2.9 4 0 0 4 4 4 1 Helix-turn-helix DNA-binding domain of SPT6 YqgF PF14639.6 KND99629.1 - 3.6e-31 108.0 0.0 1.4e-30 106.1 0.0 2.1 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 KND99629.1 - 4.3e-31 107.3 0.0 9.9e-31 106.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.6 KND99629.1 - 5.2e-20 71.8 23.6 5.2e-20 71.8 23.6 5.6 4 1 2 6 6 6 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 KND99629.1 - 5.6e-06 27.2 0.2 5.9e-05 23.9 0.2 3.0 1 1 0 1 1 1 1 HHH domain Tex_N PF09371.10 KND99629.1 - 0.02 14.6 1.4 2.5 7.7 0.0 3.3 3 0 0 3 3 3 0 Tex-like protein N-terminal domain TauD PF02668.16 KND99630.1 - 2.1e-50 172.0 0.0 2.9e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KND99630.1 - 0.0015 17.7 0.0 0.0032 16.6 0.0 1.5 1 0 0 1 1 1 1 CsiD DUF971 PF06155.12 KND99630.1 - 0.0021 18.7 0.0 0.0045 17.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) ThrE PF06738.12 KND99631.1 - 2.5e-67 226.8 14.5 1.5e-65 220.9 4.3 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KND99631.1 - 1.9e-07 31.3 9.3 1.9e-07 31.3 9.3 2.3 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE CdiA_C PF18451.1 KND99631.1 - 5.8 7.2 6.1 3.7 7.8 0.0 2.9 3 0 0 3 3 3 0 Contact-dependent growth inhibition CdiA C-terminal domain TT_ORF1 PF02956.14 KND99632.1 - 1.2 7.7 9.7 1.2 7.7 9.7 1.0 1 0 0 1 1 1 0 TT viral orf 1 PDCD2_C PF04194.13 KND99633.1 - 9.1e-39 133.3 0.8 9.8e-36 123.4 0.0 2.9 3 0 0 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain ADK_lid PF05191.14 KND99633.1 - 0.14 12.1 0.4 0.38 10.8 0.4 1.7 1 0 0 1 1 1 0 Adenylate kinase, active site lid Codanin-1_C PF15296.6 KND99633.1 - 0.74 9.9 3.3 0.43 10.7 0.4 2.0 2 0 0 2 2 2 0 Codanin-1 C-terminus GTP_EFTU PF00009.27 KND99634.1 - 3e-32 111.7 8.4 2.4e-31 108.8 3.9 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KND99634.1 - 3.3e-26 91.5 1.4 3.3e-26 91.5 1.4 2.1 2 0 0 2 2 2 1 Translation-initiation factor 2 IF2_N PF04760.15 KND99634.1 - 9.6e-11 41.3 0.0 2.1e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.23 KND99634.1 - 6.6e-09 35.8 0.2 2.1e-08 34.2 0.2 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KND99634.1 - 0.00087 18.8 0.7 0.0021 17.6 0.1 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 KND99634.1 - 0.0096 15.4 0.0 0.0096 15.4 0.0 2.0 3 0 0 3 3 3 1 ADP-ribosylation factor family GTP_EFTU_D2 PF03144.25 KND99634.1 - 0.013 15.9 0.9 4.8 7.6 0.1 3.3 2 0 0 2 2 2 0 Elongation factor Tu domain 2 MS_channel PF00924.18 KND99634.1 - 0.018 14.6 2.2 0.11 12.1 1.0 2.4 2 0 0 2 2 2 0 Mechanosensitive ion channel GTP_EFTU_D4 PF14578.6 KND99634.1 - 0.038 13.9 2.2 0.22 11.5 0.3 2.6 2 0 0 2 2 2 0 Elongation factor Tu domain 4 MMR_HSR1_Xtn PF16897.5 KND99634.1 - 0.07 13.2 0.1 0.07 13.2 0.1 2.8 3 0 0 3 3 3 0 C-terminal region of MMR_HSR1 domain Ras PF00071.22 KND99634.1 - 0.13 11.8 0.1 0.13 11.8 0.1 1.9 2 0 0 2 2 2 0 Ras family SRPRB PF09439.10 KND99634.1 - 0.76 9.2 7.4 0.057 12.9 0.6 2.5 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Dfp1_Him1_M PF08630.10 KND99635.1 - 7.2e-33 113.5 0.0 2.3e-32 111.9 0.0 2.0 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 KND99635.1 - 1.3e-21 76.5 1.4 2.4e-21 75.5 1.4 1.5 1 0 0 1 1 1 1 DBF zinc finger Parathyroid PF01279.17 KND99635.1 - 0.02 15.5 1.6 2.4 8.8 0.3 2.9 2 0 0 2 2 2 0 Parathyroid hormone family SLM4 PF16818.5 KND99636.1 - 3.4e-10 40.1 2.2 8.1e-09 35.6 2.2 2.2 1 1 0 1 1 1 1 Protein SLM4 UQ_con PF00179.26 KND99637.1 - 6.7e-41 139.2 0.0 8.7e-41 138.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KND99637.1 - 0.037 13.7 0.0 0.12 12.1 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B BTK PF00779.19 KND99637.1 - 0.25 11.2 0.3 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 BTK motif CAF1A PF12253.8 KND99637.1 - 1.1 9.5 9.8 1.9 8.7 9.8 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A SH3BGR PF04908.15 KND99640.1 - 3.2e-07 30.4 0.1 4.4e-06 26.8 0.0 3.2 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 KND99640.1 - 0.0074 16.5 0.0 0.0074 16.5 0.0 3.5 4 0 0 4 4 4 1 Glutaredoxin Hormone_3 PF00159.18 KND99640.1 - 0.058 13.5 0.0 1.5 9.0 0.0 2.7 2 0 0 2 2 2 0 Pancreatic hormone peptide KH_1 PF00013.29 KND99641.1 - 4.7e-76 250.6 24.0 4.1e-11 42.5 0.2 10.2 10 0 0 10 10 10 8 KH domain KH_4 PF13083.6 KND99641.1 - 1e-05 25.3 2.1 0.11 12.4 0.1 5.5 4 0 0 4 4 4 1 KH domain SLS PF14611.6 KND99641.1 - 0.0002 21.2 20.4 0.014 15.2 1.5 7.2 6 2 2 8 8 8 2 Mitochondrial inner-membrane-bound regulator DUF4974 PF16344.5 KND99641.1 - 0.045 13.7 0.1 8.1 6.5 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4974) EIF_2_alpha PF07541.12 KND99641.1 - 0.071 13.2 0.4 4.7 7.3 0.0 3.5 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 2 alpha subunit KH_2 PF07650.17 KND99641.1 - 0.26 11.1 23.8 3.4 7.6 1.5 6.8 6 2 1 7 7 7 0 KH domain Ribosomal_S10 PF00338.22 KND99641.1 - 0.52 10.6 0.0 0.52 10.6 0.0 3.9 5 0 0 5 5 5 0 Ribosomal protein S10p/S20e Ribosomal_S30AE PF02482.19 KND99641.1 - 2.6 8.9 8.8 8.5 7.2 0.1 5.7 5 2 1 6 6 6 0 Sigma 54 modulation protein / S30EA ribosomal protein FeoB_Cyto PF17910.1 KND99641.1 - 5.5 7.6 8.9 26 5.4 0.1 4.7 4 0 0 4 4 4 0 FeoB cytosolic helical domain AA_permease_2 PF13520.6 KND99642.1 - 1.6e-86 290.8 46.2 2e-86 290.5 46.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KND99642.1 - 3.6e-18 65.4 38.6 7.3e-18 64.4 38.7 1.3 1 1 0 1 1 1 1 Amino acid permease L51_S25_CI-B8 PF05047.16 KND99643.1 - 9.5e-06 25.4 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain IMP_cyclohyd PF07826.11 KND99643.1 - 0.0061 16.2 0.0 0.0074 15.9 0.0 1.1 1 0 0 1 1 1 1 IMP cyclohydrolase-like protein Zn_clus PF00172.18 KND99645.1 - 5e-05 23.3 9.8 5e-05 23.3 9.8 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zinc_ribbon_6 PF14599.6 KND99645.1 - 1.5 8.9 6.9 2.9 8.0 6.0 1.9 1 1 0 1 1 1 0 Zinc-ribbon TauD PF02668.16 KND99646.1 - 3.7e-60 204.0 1.7 4.6e-60 203.7 1.7 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TauD PF02668.16 KND99647.1 - 2.7e-56 191.3 3.1 3.8e-56 190.9 3.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family EF-hand_4 PF12763.7 KND99648.1 - 5.7e-24 84.1 0.0 5e-12 45.7 0.0 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand UBA PF00627.31 KND99648.1 - 1.2e-09 37.9 0.1 3.5e-09 36.4 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.32 KND99648.1 - 0.00036 19.9 0.1 0.41 10.3 0.0 3.5 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 KND99648.1 - 0.003 17.4 0.6 0.19 11.7 0.1 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 KND99648.1 - 0.0057 17.1 0.0 0.25 11.8 0.1 3.3 2 0 0 2 2 2 1 EF-hand domain pair CUE PF02845.16 KND99648.1 - 0.017 14.9 0.1 0.068 12.9 0.0 2.1 2 0 0 2 2 2 0 CUE domain MADF_DNA_bdg PF10545.9 KND99648.1 - 0.098 13.0 2.8 0.3 11.4 0.7 2.6 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3584 PF12128.8 KND99648.1 - 0.62 7.5 34.5 1.1 6.6 34.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 KND99648.1 - 1.5 7.6 41.1 0.027 13.4 24.8 2.8 1 1 2 3 3 3 0 Spc7 kinetochore protein GAS PF13851.6 KND99648.1 - 2.3 7.5 40.6 1.3 8.4 23.7 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KND99648.1 - 5.6 7.0 22.2 3.5 7.7 4.9 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4201 PF13870.6 KND99648.1 - 9.1 6.0 33.9 13 5.5 1.3 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) Gar1 PF04410.14 KND99650.1 - 3.6e-40 137.3 0.0 4.5e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region MMR_HSR1 PF01926.23 KND99651.1 - 1.3e-14 54.3 0.0 2.3e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KND99651.1 - 4.4e-06 26.4 0.1 5.9e-05 22.7 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KND99651.1 - 0.00026 21.1 0.0 0.29 11.2 0.0 2.4 2 0 0 2 2 2 2 Dynamin family SRPRB PF09439.10 KND99651.1 - 0.0005 19.5 0.0 0.00084 18.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KND99651.1 - 0.002 18.0 0.0 0.0059 16.5 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KND99651.1 - 0.0027 17.1 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 KND99651.1 - 0.0086 16.6 0.0 0.014 15.9 0.0 1.7 1 1 0 1 1 1 1 ABC transporter Septin PF00735.18 KND99651.1 - 0.017 14.5 0.0 0.038 13.3 0.0 1.6 1 1 0 1 1 1 0 Septin MecA PF05389.12 KND99651.1 - 0.017 14.7 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) FeoB_N PF02421.18 KND99651.1 - 0.025 14.1 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Gtr1_RagA PF04670.12 KND99651.1 - 0.039 13.3 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 KND99651.1 - 0.098 12.0 0.1 0.26 10.6 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family VanZ PF04892.12 KND99652.1 - 1.3e-06 29.1 0.6 1.5e-06 28.9 0.6 1.1 1 0 0 1 1 1 1 VanZ like family PLDc PF00614.22 KND99653.1 - 1.6e-17 62.9 0.3 2.8e-07 30.4 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KND99653.1 - 2.2e-12 47.0 0.0 3.5e-07 30.2 0.0 2.7 2 0 0 2 2 2 2 PLD-like domain Erv26 PF04148.13 KND99654.1 - 2.3e-75 252.9 8.9 3.6e-75 252.3 8.9 1.2 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 BCCT PF02028.17 KND99654.1 - 0.019 13.5 0.5 0.025 13.1 0.5 1.3 1 0 0 1 1 1 0 BCCT, betaine/carnitine/choline family transporter DUF3522 PF12036.8 KND99654.1 - 0.025 14.9 1.2 0.039 14.2 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) DUF2909 PF11137.8 KND99654.1 - 0.043 13.7 0.3 0.091 12.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) DctQ PF04290.12 KND99654.1 - 5.3 7.0 8.0 3.1 7.7 3.7 2.3 2 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Abhydrolase_1 PF00561.20 KND99655.1 - 9.7e-47 159.8 0.0 2.4e-46 158.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KND99655.1 - 3e-05 23.8 0.0 4.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KND99655.1 - 0.022 14.1 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MMACHC PF16690.5 KND99655.1 - 0.041 13.5 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type C family Abhydrolase_6 PF12697.7 KND99655.1 - 0.044 14.4 0.0 0.062 13.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KND99655.1 - 0.18 11.3 0.0 1.1 8.7 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Scs3p PF10261.9 KND99656.1 - 6.4e-16 58.6 4.9 2.1e-07 30.7 0.0 2.5 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM PP2C PF00481.21 KND99657.1 - 4.7e-64 216.5 0.1 7.1e-63 212.6 0.1 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C Ldh_1_C PF02866.18 KND99657.1 - 0.15 11.9 0.0 4.3 7.2 0.0 2.2 2 0 0 2 2 2 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain E1-E2_ATPase PF00122.20 KND99658.1 - 2.1e-42 144.7 1.6 2.1e-42 144.7 1.6 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KND99658.1 - 7.4e-34 117.0 5.8 7.4e-34 117.0 5.8 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KND99658.1 - 3.9e-22 79.6 0.0 2.5e-19 70.4 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KND99658.1 - 5.6e-12 45.6 0.0 1.3e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KND99658.1 - 3.4e-08 33.0 0.0 1.3e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KND99658.1 - 0.029 14.1 0.4 0.12 12.1 0.2 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF2399 PF09664.10 KND99658.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) Hydrolase_4 PF12146.8 KND99660.1 - 7.1e-41 140.0 0.0 8.7e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KND99660.1 - 1.3e-17 64.3 0.0 9.6e-17 61.5 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KND99660.1 - 2e-09 38.4 0.0 2.3e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KND99660.1 - 2.5e-05 23.8 0.0 0.093 12.2 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 KND99660.1 - 3.6e-05 23.6 0.0 0.018 14.8 0.0 3.0 3 0 0 3 3 3 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 KND99660.1 - 3.9e-05 22.7 0.0 6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 KND99660.1 - 0.00041 20.2 0.0 0.8 9.5 0.0 2.6 2 1 0 3 3 3 2 Phospholipase/Carboxylesterase Esterase PF00756.20 KND99660.1 - 0.00074 19.2 0.0 0.0017 18.0 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Chlorophyllase PF07224.11 KND99660.1 - 0.044 12.8 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase LIDHydrolase PF10230.9 KND99660.1 - 0.089 12.3 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 KND99660.1 - 0.24 11.3 0.0 0.34 10.7 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold DDE_1 PF03184.19 KND99661.1 - 5.5e-30 104.3 0.1 2.8e-29 102.0 0.1 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KND99661.1 - 3.6e-15 55.7 0.9 2.1e-14 53.3 0.3 2.6 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 KND99661.1 - 4.3e-07 29.5 0.3 2.1e-06 27.3 0.3 2.2 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain Cwf_Cwc_15 PF04889.12 KND99662.1 - 0.34 10.6 3.7 0.38 10.5 3.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF846 PF05832.12 KND99663.1 - 8.8e-54 181.3 12.1 1.1e-53 181.1 12.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Clathrin PF00637.20 KND99664.1 - 1.4e-25 89.9 2.5 1.4e-25 89.9 2.5 2.2 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.32 KND99664.1 - 0.00099 19.9 0.1 0.0037 18.1 0.1 2.1 1 0 0 1 1 1 1 WD domain, G-beta repeat Vps39_1 PF10366.9 KND99664.1 - 0.001 19.3 0.5 0.0062 16.8 0.1 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 HALZ PF02183.18 KND99664.1 - 6.3 7.1 7.0 10 6.4 0.7 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Tfb5 PF06331.12 KND99665.1 - 5.9e-24 83.8 0.2 6.5e-24 83.7 0.2 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Sec34 PF04136.15 KND99666.1 - 7.7e-35 120.0 5.7 7.7e-35 120.0 5.7 3.2 3 0 0 3 3 3 1 Sec34-like family CheX PF13690.6 KND99666.1 - 0.14 12.3 0.4 0.51 10.5 0.2 2.0 1 1 1 2 2 2 0 Chemotaxis phosphatase CheX zf-primase PF09329.11 KND99667.1 - 1.7e-11 43.7 0.7 4.4e-11 42.4 0.7 1.7 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.25 KND99667.1 - 0.00033 20.6 0.0 0.00062 19.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain POT1 PF02765.17 KND99667.1 - 0.0061 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 p450 PF00067.22 KND99669.1 - 3.2e-62 210.8 0.0 4.1e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UPF0160 PF03690.13 KND99670.1 - 3.8e-131 437.4 0.0 4.3e-131 437.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) AP_endonuc_2_N PF07582.12 KND99671.1 - 0.056 13.2 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus DUF1774 PF08611.10 KND99672.1 - 2.8e-28 98.1 3.8 2.8e-28 98.1 3.8 2.6 3 0 0 3 3 3 1 Fungal protein of unknown function (DUF1774) Pyridoxal_deC PF00282.19 KND99673.1 - 9.4e-62 208.9 0.0 1.3e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KND99673.1 - 2.6e-06 26.7 0.0 4.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V dCache_3 PF14827.6 KND99673.1 - 0.034 13.8 0.0 0.41 10.3 0.0 2.2 2 0 0 2 2 2 0 Double sensory domain of two-component sensor kinase PHO4 PF01384.20 KND99676.1 - 0.78 8.7 18.6 0.035 13.2 5.6 2.5 1 1 0 2 2 2 0 Phosphate transporter family Cse1 PF08506.10 KND99677.1 - 2e-144 481.0 12.0 2e-144 481.0 12.0 1.6 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.15 KND99677.1 - 2.1e-105 352.8 7.9 3.4e-105 352.1 7.9 1.3 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 KND99677.1 - 1.7e-13 50.3 0.1 1.5e-12 47.3 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KND99677.1 - 0.0044 17.1 4.9 0.0065 16.5 0.1 3.7 3 1 0 3 3 3 1 Exportin 1-like protein Speriolin_C PF15059.6 KND99677.1 - 0.023 14.8 0.7 0.15 12.2 0.1 2.4 2 0 0 2 2 2 0 Speriolin C-terminus Cnd1 PF12717.7 KND99677.1 - 0.29 11.1 8.4 0.055 13.5 1.6 3.3 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 CBFB_NFYA PF02045.15 KND99678.1 - 9.9e-29 99.7 7.3 1.9e-28 98.8 7.3 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B PBP_N PF17093.5 KND99678.1 - 2.3 8.5 4.6 0.76 10.0 1.1 1.9 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus Vps51 PF08700.11 KND99680.1 - 4.5e-10 39.5 1.3 2.1e-09 37.3 0.1 2.7 2 0 0 2 2 2 1 Vps51/Vps67 CMS1 PF14617.6 KND99681.1 - 9.2e-22 77.6 16.5 2e-11 43.7 4.3 2.5 1 1 2 3 3 3 2 U3-containing 90S pre-ribosomal complex subunit GIDA PF01134.22 KND99682.1 - 5.4e-125 417.5 0.0 6.7e-125 417.2 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KND99682.1 - 4.3e-62 210.0 0.0 6e-62 209.6 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain DUF3898 PF13037.6 KND99682.1 - 0.18 11.9 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3898) CENP-T_C PF15511.6 KND99683.1 - 6.4e-09 35.9 0.0 1.4e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Mito_carr PF00153.27 KND99684.1 - 6e-27 93.4 7.4 2.8e-09 36.8 0.1 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein Acetyltransf_13 PF13880.6 KND99685.1 - 9.8e-20 70.3 0.1 3e-19 68.8 0.0 1.7 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KND99685.1 - 1.5e-09 37.5 0.6 2.5e-09 36.8 0.6 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.25 KND99685.1 - 1e-05 25.8 0.0 1.6e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KND99685.1 - 3.1e-05 24.3 0.0 6.7e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KND99685.1 - 0.00064 19.7 0.0 0.0032 17.4 0.0 2.1 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_16 PF05301.11 KND99685.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 QRPTase_C PF01729.19 KND99686.1 - 8.5e-57 191.6 0.0 1.5e-56 190.8 0.0 1.4 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KND99686.1 - 3.9e-20 71.7 0.2 2.5e-19 69.1 0.0 2.4 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain FMN_dh PF01070.18 KND99686.1 - 0.062 12.3 0.0 0.075 12.0 0.0 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase SUI1 PF01253.22 KND99686.1 - 0.11 13.0 0.0 12 6.6 0.0 3.0 2 1 0 2 2 2 0 Translation initiation factor SUI1 ANAPC10 PF03256.16 KND99687.1 - 6.2e-41 140.1 0.1 3.7e-39 134.3 0.1 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) SMI1_KNR4 PF09346.10 KND99688.1 - 9.9e-32 110.1 0.0 2.8e-31 108.6 0.0 1.8 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) GCS PF03074.16 KND99689.1 - 3e-144 480.9 0.0 4.2e-144 480.4 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 KND99689.1 - 0.15 11.4 0.0 0.35 10.2 0.0 1.5 2 0 0 2 2 2 0 Glutamate-cysteine ligase family 2(GCS2) GARS_A PF01071.19 KND99691.1 - 4.4e-80 268.0 0.0 9.6e-80 266.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 KND99691.1 - 3.1e-35 121.6 0.1 7.1e-35 120.4 0.1 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 KND99691.1 - 1.6e-33 115.3 0.2 2.3e-32 111.6 0.0 3.0 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 KND99691.1 - 1.2e-24 86.4 1.6 2.6e-24 85.3 1.6 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KND99691.1 - 1.5e-15 57.6 3.3 8.3e-15 55.2 3.6 2.1 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 KND99691.1 - 0.0001 21.9 0.0 0.00022 20.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KND99691.1 - 0.00011 22.2 0.1 0.00063 19.8 0.0 2.3 3 0 0 3 3 3 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KND99691.1 - 0.0058 16.2 0.1 0.012 15.2 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 KND99691.1 - 0.28 10.8 2.6 0.59 9.7 0.0 2.7 4 0 0 4 4 4 0 RimK-like ATP-grasp domain Ribonucleas_3_3 PF14622.6 KND99693.1 - 0.00017 21.7 0.2 0.00049 20.3 0.2 1.8 1 1 1 2 2 2 1 Ribonuclease-III-like dsrm PF00035.26 KND99693.1 - 0.0013 19.4 0.0 0.0033 18.1 0.0 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif EXS PF03124.14 KND99695.1 - 2.1e-60 204.8 23.4 2.5e-60 204.6 23.4 1.0 1 0 0 1 1 1 1 EXS family Nop25 PF09805.9 KND99697.1 - 4.5e-35 121.1 27.8 4.5e-35 121.1 27.8 2.2 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) CytadhesinP1 PF12378.8 KND99697.1 - 0.95 9.7 0.1 0.95 9.7 0.1 2.6 3 1 0 3 3 3 0 Trypsin-sensitive surface-exposed protein Sas10_Utp3 PF04000.15 KND99698.1 - 1.5e-11 44.8 4.1 2.1e-11 44.3 0.0 2.6 2 1 1 3 3 3 1 Sas10/Utp3/C1D family DUF2802 PF10975.8 KND99698.1 - 0.0022 18.1 0.1 0.0022 18.1 0.1 3.0 3 1 1 4 4 4 1 Protein of unknown function (DUF2802) DUF2951 PF11166.8 KND99698.1 - 0.069 13.4 0.6 0.2 11.9 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Ribonuc_2-5A PF06479.12 KND99699.1 - 1.7e-44 151.1 1.0 4.7e-44 149.6 0.3 2.1 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase PF00069.25 KND99699.1 - 4.1e-39 134.5 0.0 2.2e-29 102.6 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND99699.1 - 2e-21 76.5 0.0 5.4e-20 71.8 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KND99699.1 - 4.1e-06 25.8 2.0 6.9e-05 21.8 0.1 2.8 3 1 0 3 3 3 1 Fungal protein kinase PQQ_2 PF13360.6 KND99699.1 - 4.9e-05 23.0 0.0 0.0075 15.9 0.0 2.8 1 1 1 2 2 2 1 PQQ-like domain PQQ PF01011.21 KND99699.1 - 0.0003 20.6 0.0 1.3 9.1 0.0 3.2 3 0 0 3 3 3 2 PQQ enzyme repeat Kdo PF06293.14 KND99699.1 - 0.048 13.0 0.1 0.081 12.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KND99699.1 - 0.095 12.3 0.1 2.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KND99699.1 - 0.13 11.6 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pns11_12 PF17464.2 KND99699.1 - 4.1 7.1 10.4 0.54 9.9 6.2 1.6 2 0 0 2 2 2 0 Non-structural protein 11 and 12 VASt PF16016.5 KND99700.1 - 3.6e-39 134.6 0.2 6.5e-39 133.8 0.2 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KND99700.1 - 2.8e-27 94.9 0.1 6.2e-27 93.7 0.1 1.5 1 0 0 1 1 1 1 GRAM domain Orthopox_F8 PF05886.11 KND99700.1 - 0.17 12.0 0.6 0.86 9.8 0.3 2.3 2 0 0 2 2 2 0 Orthopoxvirus F8 protein SurE PF01975.17 KND99701.1 - 8e-42 143.2 0.0 1.1e-41 142.8 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE MF_alpha_N PF05436.11 KND99701.1 - 0.084 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus HSF_DNA-bind PF00447.17 KND99703.1 - 1.5e-29 102.5 1.7 1.5e-29 102.5 1.7 2.2 2 0 0 2 2 2 1 HSF-type DNA-binding BCS1_N PF08740.11 KND99704.1 - 8.2e-46 156.3 0.0 1.2e-45 155.8 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KND99704.1 - 5.7e-22 78.6 0.0 9.3e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KND99704.1 - 0.00099 19.5 0.0 0.0045 17.4 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KND99704.1 - 0.0015 17.7 0.0 0.0024 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 KND99704.1 - 0.002 17.6 0.0 0.0043 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 KND99704.1 - 0.0071 16.9 0.0 0.013 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KND99704.1 - 0.0087 15.8 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KND99704.1 - 0.012 15.8 0.0 0.021 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KND99704.1 - 0.015 15.3 0.0 0.04 13.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KND99704.1 - 0.043 14.1 0.1 0.25 11.6 0.0 2.2 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 KND99704.1 - 0.045 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 KND99704.1 - 0.054 14.0 0.0 0.094 13.2 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Rad17 PF03215.15 KND99704.1 - 0.06 13.3 0.0 0.47 10.4 0.0 2.3 2 1 1 3 3 3 0 Rad17 P-loop domain AAA_29 PF13555.6 KND99704.1 - 0.079 12.7 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.6 KND99704.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KND99704.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain SL4P PF17618.2 KND99704.1 - 0.14 12.2 0.1 0.34 11.0 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein AAA_28 PF13521.6 KND99704.1 - 0.19 12.0 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KND99704.1 - 0.19 11.1 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_11 PF13086.6 KND99704.1 - 0.21 11.3 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain UCH PF00443.29 KND99707.1 - 1.4e-45 155.9 1.5 2.7e-45 154.9 1.5 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 KND99707.1 - 3.1e-39 132.7 6.8 9.6e-15 54.3 0.4 5.4 3 1 2 5 5 5 5 A repeated domain in UCH-protein UCH_1 PF13423.6 KND99707.1 - 0.013 15.1 14.9 0.036 13.7 11.2 3.0 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Csm1_N PF18504.1 KND99707.1 - 0.07 13.5 2.0 1.4 9.3 0.3 3.1 3 0 0 3 3 3 0 Csm1 N-terminal domain ABC2_membrane PF01061.24 KND99708.1 - 1.4e-38 132.4 11.7 1.4e-38 132.4 11.7 1.8 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 KND99708.1 - 9.1e-29 100.7 0.0 2.4e-28 99.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KND99708.1 - 3.9e-07 29.5 15.8 9.2e-07 28.3 15.8 1.6 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 KND99708.1 - 3.5e-06 27.1 0.0 0.039 13.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 KND99708.1 - 0.0089 16.0 0.3 0.36 10.7 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KND99708.1 - 0.013 15.8 0.0 0.027 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KND99708.1 - 0.014 15.1 0.1 0.041 13.6 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KND99708.1 - 0.027 14.4 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ABC2_membrane_2 PF12679.7 KND99708.1 - 0.034 13.4 6.8 0.082 12.2 6.8 1.6 1 0 0 1 1 1 0 ABC-2 family transporter protein SMC_N PF02463.19 KND99708.1 - 0.055 12.9 0.0 0.44 9.9 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 KND99708.1 - 0.11 12.7 0.2 0.21 11.8 0.2 1.4 1 0 0 1 1 1 0 AAA domain IL1_propep PF02394.16 KND99708.1 - 0.16 12.9 0.3 0.41 11.6 0.3 1.7 1 0 0 1 1 1 0 Interleukin-1 propeptide AAA_22 PF13401.6 KND99708.1 - 0.17 12.2 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KND99708.1 - 0.25 11.8 0.7 0.75 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2955 PF11168.8 KND99708.1 - 0.72 9.7 7.7 0.27 11.1 4.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2955) Form-deh_trans PF09163.11 KND99708.1 - 0.78 9.6 2.8 2.6 7.9 2.8 1.9 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane Epimerase PF01370.21 KND99709.1 - 9.4e-14 51.5 0.0 1.5e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KND99709.1 - 2.7e-09 36.4 0.0 3.7e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KND99709.1 - 2.5e-05 24.3 0.0 5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KND99709.1 - 6.1e-05 22.6 0.1 0.00011 21.7 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KND99709.1 - 7.5e-05 22.3 0.0 0.00016 21.2 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KND99709.1 - 0.0045 16.2 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KND99709.1 - 0.0098 15.5 0.3 0.096 12.2 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family MucBP_2 PF17965.1 KND99709.1 - 0.082 13.5 0.2 1.5 9.4 0.2 2.5 1 1 0 1 1 1 0 Mucin binding domain DUF1776 PF08643.10 KND99709.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Svf1 PF08622.10 KND99711.1 - 2.6e-66 222.7 0.1 4.1e-66 222.1 0.1 1.3 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Svf1_C PF17187.4 KND99711.1 - 4.8e-62 208.6 0.5 8.6e-62 207.8 0.5 1.4 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain CrtC PF07143.11 KND99711.1 - 0.099 13.3 0.0 0.19 12.4 0.0 1.5 1 0 0 1 1 1 0 CrtC N-terminal lipocalin domain DUF1151 PF06625.11 KND99715.1 - 0.014 15.3 1.4 0.014 15.3 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) Ku_C PF03730.14 KND99715.1 - 0.1 13.3 5.1 0.22 12.3 1.6 2.4 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm Actin PF00022.19 KND99718.1 - 5.6e-22 77.9 0.1 2.4e-13 49.5 0.1 4.4 3 1 0 3 3 3 2 Actin Actin_micro PF17003.5 KND99718.1 - 1.8e-07 30.7 0.3 0.0016 17.7 0.1 2.5 2 0 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 KND99718.1 - 5.9e-05 22.0 0.3 0.0036 16.2 0.2 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KND99718.1 - 0.0069 16.8 0.2 0.02 15.3 0.2 2.0 1 1 0 1 1 1 1 Cell division protein FtsA NOA36 PF06524.12 KND99718.1 - 0.29 10.4 15.6 0.93 8.8 15.6 1.8 1 0 0 1 1 1 0 NOA36 protein OrfB_IS605 PF01385.19 KND99718.1 - 0.33 11.2 2.3 0.58 10.4 0.1 2.3 2 0 0 2 2 2 0 Probable transposase DNA_pol_phi PF04931.13 KND99718.1 - 0.67 8.0 14.6 0.0057 14.8 5.8 1.8 2 0 0 2 2 2 0 DNA polymerase phi CoA_binding PF02629.19 KND99719.1 - 2.2e-25 89.2 2.8 2.2e-25 89.2 2.8 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KND99719.1 - 2.4e-25 89.1 0.0 4.6e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KND99719.1 - 2.6e-06 27.3 0.0 4.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KND99719.1 - 1.2e-05 25.8 0.1 2.9e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 CoA binding domain IGR PF09597.10 KND99720.1 - 1e-21 76.8 3.9 1.1e-21 76.6 0.3 2.4 3 0 0 3 3 3 1 IGR protein motif Pro_isomerase PF00160.21 KND99721.1 - 2.5e-43 148.1 0.1 3.2e-43 147.7 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Med6 PF04934.14 KND99722.1 - 7.5e-52 174.7 0.7 1.1e-51 174.1 0.7 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component HIT PF01230.23 KND99723.1 - 1.3e-23 83.6 0.0 2e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KND99723.1 - 3.4e-05 24.3 0.0 4.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KND99723.1 - 0.013 15.4 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 SPOB_a PF14689.6 KND99723.1 - 0.03 14.0 0.1 0.061 13.0 0.1 1.4 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain AhpC-TSA PF00578.21 KND99724.1 - 1.6e-33 115.2 0.0 2.2e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KND99724.1 - 4e-16 59.0 0.0 5.3e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KND99724.1 - 1.5e-12 47.1 0.0 3.5e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 KND99724.1 - 0.00031 20.6 0.0 0.0011 18.9 0.0 1.8 2 0 0 2 2 2 1 SCO1/SenC DUF5341 PF17276.2 KND99725.1 - 5.9e-20 72.1 11.5 1.4e-10 41.6 3.4 2.8 2 1 1 3 3 3 2 Family of unknown function (DUF5341) AAA PF00004.29 KND99726.1 - 1.1e-51 174.7 0.7 4.9e-38 130.5 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KND99726.1 - 1.9e-10 41.1 0.7 0.00013 22.2 0.1 4.0 3 2 1 4 4 3 2 AAA domain AAA_lid_3 PF17862.1 KND99726.1 - 3.9e-10 39.4 0.0 1.1e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KND99726.1 - 1.6e-09 38.4 0.0 0.00047 20.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 KND99726.1 - 7e-09 35.6 0.2 0.00091 19.0 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain CDC48_N PF02359.18 KND99726.1 - 1.2e-07 31.9 0.0 4.1e-07 30.1 0.0 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_5 PF07728.14 KND99726.1 - 1.7e-07 31.4 0.3 0.0027 17.7 0.1 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KND99726.1 - 4.7e-07 30.1 0.1 7.8e-05 22.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 KND99726.1 - 4.6e-06 26.5 0.0 0.031 14.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 KND99726.1 - 8.2e-06 25.6 0.1 0.024 14.4 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain TIP49 PF06068.13 KND99726.1 - 8.8e-06 25.1 0.7 0.12 11.6 0.0 2.7 3 0 0 3 3 3 2 TIP49 P-loop domain Mg_chelatase PF01078.21 KND99726.1 - 1.2e-05 24.8 0.6 0.008 15.6 0.2 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KND99726.1 - 3e-05 24.4 0.0 0.16 12.4 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_18 PF13238.6 KND99726.1 - 3e-05 24.6 0.3 0.028 15.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_3 PF07726.11 KND99726.1 - 5e-05 23.2 0.0 0.041 13.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KND99726.1 - 5.3e-05 23.0 0.0 0.12 12.1 0.0 2.7 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 KND99726.1 - 5.3e-05 22.8 0.0 0.071 12.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region TsaE PF02367.17 KND99726.1 - 6.3e-05 23.0 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KND99726.1 - 9.9e-05 21.6 0.1 0.14 11.4 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain TniB PF05621.11 KND99726.1 - 0.00027 20.4 1.0 0.55 9.6 0.0 3.8 3 2 1 4 4 3 1 Bacterial TniB protein ATPase PF06745.13 KND99726.1 - 0.00052 19.4 1.1 0.06 12.7 0.1 3.1 2 1 1 3 3 3 1 KaiC ABC_tran PF00005.27 KND99726.1 - 0.00057 20.4 0.1 0.14 12.7 0.1 2.7 2 0 0 2 2 2 1 ABC transporter CDC48_2 PF02933.17 KND99726.1 - 0.00072 19.3 0.9 0.017 14.9 0.1 2.8 3 0 0 3 3 2 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.6 KND99726.1 - 0.00091 19.3 0.2 0.32 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KND99726.1 - 0.0014 18.0 0.1 0.26 10.5 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 KND99726.1 - 0.0015 18.5 0.1 0.97 9.3 0.0 2.8 2 1 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 KND99726.1 - 0.0016 18.6 0.0 0.65 10.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 KND99726.1 - 0.0022 17.6 0.2 2.8 7.5 0.0 3.0 2 1 0 3 3 3 1 AAA domain Torsin PF06309.11 KND99726.1 - 0.004 17.2 0.0 0.9 9.6 0.0 3.3 3 0 0 3 3 3 1 Torsin AAA_11 PF13086.6 KND99726.1 - 0.0075 16.1 0.0 0.52 10.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 KND99726.1 - 0.0078 15.7 0.0 3 7.3 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein Parvo_NS1 PF01057.17 KND99726.1 - 0.0081 15.3 0.0 0.7 8.9 0.0 2.5 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 DEAD PF00270.29 KND99726.1 - 0.0085 15.9 0.9 3.1 7.5 0.1 3.3 2 2 1 3 3 3 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KND99726.1 - 0.0095 16.3 0.1 1.1 9.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KND99726.1 - 0.017 14.4 0.0 0.36 10.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Sigma54_activ_2 PF14532.6 KND99726.1 - 0.021 14.9 0.0 5.8 7.0 0.0 2.9 2 1 0 2 2 2 0 Sigma-54 interaction domain Rad17 PF03215.15 KND99726.1 - 0.029 14.3 0.0 0.37 10.7 0.0 2.5 2 1 0 2 2 2 0 Rad17 P-loop domain AAA_30 PF13604.6 KND99726.1 - 0.036 13.8 0.0 2.7 7.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_17 PF13207.6 KND99726.1 - 0.046 14.1 0.1 18 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 KND99726.1 - 0.052 12.7 0.0 2.6 7.1 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NTPase_1 PF03266.15 KND99726.1 - 0.11 12.5 0.2 22 4.9 0.0 2.6 2 0 0 2 2 2 0 NTPase W2 PF02020.18 KND99727.1 - 0.012 15.8 0.3 0.035 14.3 0.3 1.8 1 0 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon Hydin_ADK PF17213.3 KND99727.1 - 0.16 12.2 2.0 0.26 11.6 2.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Aldo_ket_red PF00248.21 KND99729.1 - 7.1e-37 127.2 0.0 1e-36 126.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family MRP-S28 PF10213.9 KND99731.1 - 3.7e-34 117.9 1.2 6.4e-34 117.1 1.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF1086 PF06461.11 KND99731.1 - 0.0098 15.7 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) Ada3 PF10198.9 KND99733.1 - 1e-38 132.5 4.0 1e-38 132.5 4.0 2.5 3 1 0 3 3 3 1 Histone acetyltransferases subunit 3 DUF4778 PF16008.5 KND99733.1 - 2.5 8.1 10.4 0.27 11.3 5.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) Peptidase_M16 PF00675.20 KND99734.1 - 7.3e-48 162.3 0.1 3.7e-46 156.8 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KND99734.1 - 1e-29 103.8 0.0 2.1e-29 102.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain RPA_interact_M PF14767.6 KND99734.1 - 0.043 14.4 0.1 0.15 12.6 0.0 1.9 2 0 0 2 2 2 0 Replication protein A interacting middle Syntaxin-6_N PF09177.11 KND99734.1 - 0.13 12.8 3.1 0.95 10.1 0.5 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal PRELI PF04707.14 KND99737.1 - 7.4e-48 162.3 0.0 9.1e-48 162.0 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family Diphtheria_C PF02763.14 KND99737.1 - 0.016 14.9 0.1 0.026 14.2 0.1 1.3 1 0 0 1 1 1 0 Diphtheria toxin, C domain Phosducin PF02114.16 KND99740.1 - 7.8e-09 34.9 0.2 9.4e-09 34.6 0.2 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 KND99740.1 - 4e-06 26.8 0.1 7.2e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Mt_ATP_synt PF15704.5 KND99740.1 - 0.062 13.2 4.6 0.084 12.8 4.6 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase subunit ubiquitin PF00240.23 KND99742.1 - 3.4e-34 116.4 0.6 7.4e-34 115.3 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 KND99742.1 - 1.7e-26 92.1 2.2 4.2e-26 90.8 2.2 1.7 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KND99742.1 - 2.2e-16 59.4 0.8 4.6e-16 58.4 0.7 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KND99742.1 - 2.3e-05 24.8 0.4 0.00012 22.5 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KND99742.1 - 0.0014 18.7 0.3 0.0031 17.6 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KND99742.1 - 0.0037 17.6 0.4 0.0075 16.6 0.0 1.6 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KND99742.1 - 0.0053 16.7 0.0 0.0078 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DZR PF12773.7 KND99742.1 - 0.0059 16.6 1.1 0.013 15.5 1.1 1.5 1 1 0 1 1 1 1 Double zinc ribbon DUF2407 PF10302.9 KND99742.1 - 0.012 16.1 0.5 0.017 15.7 0.5 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KND99742.1 - 0.018 15.1 1.0 5.6 7.1 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain zinc_ribbon_5 PF13719.6 KND99742.1 - 0.21 11.4 2.9 2.5 7.9 0.1 2.7 2 1 0 2 2 2 0 zinc-ribbon domain Auto_anti-p27 PF06677.12 KND99742.1 - 0.35 11.0 1.9 0.53 10.5 1.3 1.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zinc_ribbon_2 PF13240.6 KND99742.1 - 1.3 8.8 6.7 1.8 8.4 0.6 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Sec10 PF07393.11 KND99743.1 - 2.4e-167 558.5 15.5 3.2e-167 558.1 15.5 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 BLOC1_2 PF10046.9 KND99743.1 - 0.0024 18.1 6.4 0.11 12.8 2.4 3.2 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 FAM184 PF15665.5 KND99743.1 - 0.0039 17.0 4.1 0.004 17.0 2.3 1.9 2 0 0 2 2 2 1 Family with sequence similarity 184, A and B Vps51 PF08700.11 KND99743.1 - 0.0085 16.2 5.5 0.051 13.6 1.0 3.1 2 0 0 2 2 2 1 Vps51/Vps67 DUF2730 PF10805.8 KND99743.1 - 0.009 16.1 2.6 1.3 9.1 0.9 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2730) Occludin_ELL PF07303.13 KND99743.1 - 0.074 13.8 2.5 1.3 9.7 0.1 3.9 2 1 1 3 3 3 0 Occludin homology domain DUF16 PF01519.16 KND99743.1 - 0.11 13.1 8.6 0.26 11.8 1.5 3.8 4 0 0 4 4 4 0 Protein of unknown function DUF16 DUF2894 PF11445.8 KND99743.1 - 0.18 12.2 0.3 0.96 9.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) APAF1_C PF17908.1 KND99743.1 - 0.47 10.4 4.4 0.3 11.1 0.9 2.5 2 0 0 2 2 2 0 APAF-1 helical domain Lebercilin PF15619.6 KND99743.1 - 0.6 9.7 7.3 6.3 6.4 3.0 2.6 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Laminin_II PF06009.12 KND99743.1 - 1.4 8.9 4.5 2.3 8.3 1.5 2.8 2 0 0 2 2 2 0 Laminin Domain II DUF148 PF02520.17 KND99743.1 - 2.9 8.0 14.2 0.57 10.3 1.1 4.3 4 0 0 4 4 4 0 Domain of unknown function DUF148 DUF1664 PF07889.12 KND99743.1 - 4.7 7.3 5.5 3.6 7.6 0.9 3.0 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 KND99743.1 - 5.7 7.3 8.8 0.57 10.5 0.9 3.2 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Metallophos PF00149.28 KND99744.1 - 7.5e-15 56.0 1.0 1.2e-14 55.3 1.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KND99744.1 - 0.013 15.7 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain SAS4 PF15460.6 KND99745.1 - 1.3e-29 102.2 2.0 1.3e-29 102.2 2.0 2.5 4 0 0 4 4 4 1 Something about silencing, SAS, complex subunit 4 Nipped-B_C PF12830.7 KND99746.1 - 6e-38 130.7 0.4 6e-38 130.7 0.4 4.4 5 1 0 5 5 5 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KND99746.1 - 1.6 9.1 8.2 0.45 10.9 3.4 2.7 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion DHHC PF01529.20 KND99748.1 - 1.8e-31 109.0 15.2 1.8e-31 109.0 15.2 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase ATP-synt_I PF03899.15 KND99748.1 - 0.18 12.2 11.9 2.6 8.5 1.0 2.6 2 1 0 2 2 2 0 ATP synthase I chain Ca_bind_SSO6904 PF18249.1 KND99749.1 - 0.095 13.1 0.1 0.31 11.4 0.1 1.8 1 0 0 1 1 1 0 Calcium binding protein SSO6904 CybS PF05328.12 KND99750.1 - 8e-50 168.0 0.0 9.1e-50 167.8 0.0 1.0 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit PCI PF01399.27 KND99751.1 - 0.0016 18.9 0.1 0.0035 17.8 0.0 1.6 2 0 0 2 2 2 1 PCI domain RTT107_BRCT_5 PF16770.5 KND99751.1 - 0.061 13.2 0.0 0.19 11.6 0.0 1.9 2 1 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain PXA PF02194.15 KND99752.1 - 5.5e-29 101.4 0.4 1.2e-28 100.3 0.4 1.6 1 0 0 1 1 1 1 PXA domain BPL_LplA_LipB PF03099.19 KND99754.1 - 3.5e-10 39.9 0.1 5.2e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DASH_Spc19 PF08287.11 KND99755.1 - 2.2e-33 115.4 12.1 4.4e-33 114.4 12.1 1.5 1 1 0 1 1 1 1 Spc19 DUF1843 PF08898.10 KND99755.1 - 0.097 13.2 0.3 0.31 11.6 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) HAUS-augmin3 PF14932.6 KND99755.1 - 0.28 10.7 5.8 0.38 10.3 5.8 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 FHA PF00498.26 KND99756.1 - 7.7e-10 39.0 0.7 6.7e-08 32.8 0.1 2.7 2 0 0 2 2 2 1 FHA domain zf-C4H2 PF10146.9 KND99756.1 - 0.0042 17.4 6.2 0.0072 16.7 6.2 1.4 1 0 0 1 1 1 1 Zinc finger-containing protein Yop-YscD_cpl PF16697.5 KND99756.1 - 0.016 15.5 0.8 0.059 13.7 0.0 2.4 3 0 0 3 3 2 0 Inner membrane component of T3SS, cytoplasmic domain DivIC PF04977.15 KND99756.1 - 0.043 13.6 9.6 0.49 10.2 0.3 2.6 2 0 0 2 2 2 0 Septum formation initiator BBP1_C PF15272.6 KND99756.1 - 0.049 13.5 9.5 0.36 10.6 9.5 2.3 2 1 0 2 2 2 0 Spindle pole body component BBP1, C-terminal ParE-like_toxin PF15781.5 KND99756.1 - 0.071 13.1 0.4 0.23 11.5 0.2 2.0 2 0 0 2 2 2 0 ParE-like toxin of type II bacterial toxin-antitoxin system DUF2205 PF10224.9 KND99756.1 - 0.085 12.9 12.3 0.091 12.8 1.0 2.7 2 0 0 2 2 2 0 Short coiled-coil protein Fib_alpha PF08702.10 KND99756.1 - 0.085 13.0 11.6 0.091 12.9 9.9 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HAUS6_N PF14661.6 KND99756.1 - 0.1 12.2 4.8 0.18 11.4 4.8 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF16 PF01519.16 KND99756.1 - 0.11 12.9 9.8 0.14 12.6 6.2 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF4200 PF13863.6 KND99756.1 - 0.2 12.1 13.5 3.4 8.1 13.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF641 PF04859.12 KND99756.1 - 0.2 12.0 7.7 0.56 10.5 7.6 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) LMBR1 PF04791.16 KND99756.1 - 0.39 9.6 1.4 0.47 9.3 1.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Halogen_Hydrol PF10112.9 KND99756.1 - 0.46 10.5 7.2 3.8 7.5 6.6 2.3 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Spc7 PF08317.11 KND99756.1 - 0.62 8.9 15.4 0.1 11.4 11.7 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 KND99756.1 - 0.65 10.3 8.4 7.5 6.9 0.6 2.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.19 KND99756.1 - 0.85 7.5 10.2 0.21 9.5 3.4 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Swi5 PF07061.11 KND99756.1 - 1.3 9.1 9.7 5.4 7.2 1.9 2.9 2 1 0 2 2 2 0 Swi5 Fzo_mitofusin PF04799.13 KND99756.1 - 4.7 6.7 11.4 4.5 6.8 6.7 2.3 1 1 1 2 2 2 0 fzo-like conserved region NPV_P10 PF05531.12 KND99756.1 - 6.6 7.3 9.6 5.4 7.5 1.5 2.9 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein ZapB PF06005.12 KND99756.1 - 6.6 7.3 14.8 17 5.9 7.3 2.8 2 0 0 2 2 2 0 Cell division protein ZapB Coq4 PF05019.13 KND99757.1 - 3.7e-98 327.3 0.0 4.7e-98 326.9 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 GyrI-like PF06445.15 KND99757.1 - 0.089 13.1 0.0 0.91 9.8 0.0 2.1 2 0 0 2 2 2 0 GyrI-like small molecule binding domain DUF4570 PF15134.6 KND99757.1 - 0.13 12.2 0.4 6.2 6.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) DUF4112 PF13430.6 KND99759.1 - 3.7e-18 65.7 0.1 4.2e-18 65.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) IIGP PF05049.13 KND99760.1 - 0.011 14.9 0.7 0.012 14.7 0.7 1.0 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF1296 PF06972.11 KND99760.1 - 0.046 13.9 0.1 0.1 12.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1296) MSA-2c PF12238.8 KND99760.1 - 0.05 13.6 2.1 0.052 13.5 2.1 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c Alpha_adaptinC2 PF02883.20 KND99761.1 - 6.3e-17 61.9 0.5 1.1e-16 61.1 0.0 1.7 2 0 0 2 2 2 1 Adaptin C-terminal domain GAT PF03127.14 KND99761.1 - 3.3e-16 59.4 0.6 7.6e-16 58.2 0.1 2.0 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 KND99761.1 - 1.3e-06 27.9 0.2 4.1e-06 26.3 0.2 1.9 1 0 0 1 1 1 1 GGA N-GAT domain Hrs_helical PF12210.8 KND99761.1 - 0.00091 19.7 0.2 0.003 18.0 0.1 2.0 2 0 0 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate Pannexin_like PF12534.8 KND99762.1 - 1.2 8.2 3.2 1.5 7.9 3.2 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF2116 PF09889.9 KND99765.1 - 0.0006 19.7 0.2 0.00073 19.5 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) NapE PF06796.11 KND99765.1 - 0.038 13.5 0.1 0.052 13.1 0.1 1.2 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE GATase_2 PF00310.21 KND99766.1 - 2.1e-175 583.5 0.0 3e-175 583.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KND99766.1 - 1.4e-151 504.9 0.0 2.9e-151 503.8 0.0 1.6 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KND99766.1 - 2.3e-112 375.0 0.0 8.5e-112 373.2 0.0 1.8 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KND99766.1 - 1.2e-82 276.2 4.0 1.9e-82 275.5 4.0 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.6 KND99766.1 - 3.3e-22 78.4 0.3 7.2e-22 77.3 0.3 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 KND99766.1 - 1e-20 74.2 0.2 2.2e-19 69.8 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KND99766.1 - 5.5e-10 39.7 0.0 1.7e-06 28.5 0.0 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KND99766.1 - 3.7e-09 36.7 0.0 1.6e-08 34.6 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KND99766.1 - 2.9e-06 26.9 0.0 5.2e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 KND99766.1 - 3.6e-05 23.1 0.1 0.00029 20.2 0.0 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KND99766.1 - 7.3e-05 22.2 0.1 0.00016 21.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KND99766.1 - 8.4e-05 21.4 0.1 8.4e-05 21.4 0.1 1.9 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 KND99766.1 - 8.6e-05 22.3 0.2 0.00063 19.4 0.1 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KND99766.1 - 9e-05 21.7 0.0 0.00027 20.2 0.0 1.9 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KND99766.1 - 0.00029 20.3 0.0 0.00081 18.8 0.0 1.8 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KND99766.1 - 0.00034 20.0 0.1 0.11 11.8 0.0 2.7 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KND99766.1 - 0.00072 20.0 0.6 0.34 11.4 0.0 2.9 2 0 0 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KND99766.1 - 0.0052 16.2 0.1 0.062 12.7 0.0 2.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KND99766.1 - 0.02 14.0 0.6 0.09 11.8 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KND99766.1 - 0.061 12.6 0.0 1.6 8.0 0.0 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_hydro_65C PF03633.15 KND99766.1 - 0.071 13.0 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain DUF3336 PF11815.8 KND99766.1 - 0.085 12.6 0.0 0.35 10.6 0.1 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF3336) Lycopene_cycl PF05834.12 KND99766.1 - 0.11 11.5 0.1 0.23 10.5 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.23 KND99766.1 - 0.13 12.3 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF5452 PF17533.2 KND99767.1 - 0.043 13.9 0.0 0.05 13.7 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5452) DUF4653 PF15546.6 KND99768.1 - 0.15 11.6 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) RNase_PH PF01138.21 KND99769.1 - 2.4e-14 54.0 0.1 9.7e-13 48.8 0.0 2.6 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 StbA PF06406.11 KND99769.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 StbA protein UCH PF00443.29 KND99770.1 - 4.7e-72 242.6 0.2 9.1e-72 241.6 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KND99770.1 - 1.2e-13 51.4 3.7 1e-05 25.3 1.1 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase CW_binding_1 PF01473.20 KND99770.1 - 0.025 14.9 1.5 0.088 13.2 1.5 1.9 1 0 0 1 1 1 0 Putative cell wall binding repeat Apidaecin PF00807.17 KND99770.1 - 0.44 10.7 0.0 0.44 10.7 0.0 2.8 3 0 0 3 3 3 0 Apidaecin Beach PF02138.18 KND99771.1 - 3.7e-121 403.7 1.0 1.6e-120 401.6 0.2 2.2 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 KND99771.1 - 2.7e-11 43.4 0.0 8.1e-11 41.9 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH TPT PF03151.16 KND99772.1 - 1.1e-23 84.0 20.4 1.4e-11 44.3 10.6 2.8 2 1 0 2 2 2 2 Triose-phosphate Transporter family AOX PF01786.17 KND99772.1 - 0.075 12.6 0.1 0.19 11.3 0.1 1.6 1 1 0 1 1 1 0 Alternative oxidase DUF2012 PF09430.10 KND99773.1 - 0.00031 20.9 0.0 0.00045 20.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) SOP4 PF17081.5 KND99773.1 - 0.0019 17.7 0.1 0.13 11.8 0.1 2.1 2 0 0 2 2 2 2 Suppressor of PMA 1-7 protein MFS_1 PF07690.16 KND99774.1 - 1.7e-31 109.5 56.4 1e-22 80.6 33.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND99774.1 - 0.66 8.8 41.0 0.042 12.7 12.8 2.8 2 2 0 2 2 2 0 Sugar (and other) transporter DUF3445 PF11927.8 KND99776.1 - 5.7e-63 212.6 0.3 7.1e-63 212.3 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Ribosomal_S11 PF00411.19 KND99777.1 - 1.6e-46 157.3 1.8 1.9e-46 157.0 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2767 PF10965.8 KND99781.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2767) Peptidase_M1 PF01433.20 KND99782.1 - 1.9e-48 164.9 0.4 2.9e-48 164.3 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KND99782.1 - 7.2e-35 119.5 0.0 1.7e-34 118.3 0.0 1.7 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KND99782.1 - 8.1e-27 94.6 0.0 1.2e-26 94.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 KND99782.1 - 0.042 13.5 0.1 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 Peptidase MA superfamily Peptidase_M61 PF05299.12 KND99782.1 - 1.2 9.6 4.9 6 7.3 1.8 3.0 2 1 0 2 2 2 0 M61 glycyl aminopeptidase Sel1 PF08238.12 KND99783.1 - 2.9e-10 40.5 6.5 0.0047 17.6 2.2 3.5 3 0 0 3 3 3 3 Sel1 repeat SAC3_GANP PF03399.16 KND99785.1 - 2.1e-17 63.5 2.8 1.6e-15 57.2 2.6 2.5 1 1 0 1 1 1 1 SAC3/GANP family TFIIA PF03153.13 KND99785.1 - 4.5 7.2 30.3 9.9 6.0 30.3 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_C12 PF01088.21 KND99786.1 - 3.3e-52 177.3 0.0 3.9e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 U6-snRNA_bdg PF10596.9 KND99787.1 - 0.027 14.4 1.5 0.71 9.8 0.4 2.3 2 0 0 2 2 2 0 U6-snRNA interacting domain of PrP8 Pkinase PF00069.25 KND99788.1 - 4e-73 246.0 0.2 5.2e-73 245.7 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND99788.1 - 1.2e-42 146.0 0.0 1.6e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND99788.1 - 3.2e-05 23.4 0.0 7.1e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KND99788.1 - 0.0008 18.3 0.0 0.0018 17.1 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KND99788.1 - 0.0093 14.9 0.4 0.015 14.3 0.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_C PF00433.24 KND99788.1 - 0.031 15.0 0.3 0.099 13.4 0.3 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain GramPos_pilinBB PF16569.5 KND99788.1 - 0.052 14.4 0.3 0.12 13.1 0.3 1.6 1 0 0 1 1 1 0 Gram-positive pilin backbone subunit 2, Cna-B-like domain PX PF00787.24 KND99791.1 - 8.6e-09 35.4 0.3 2.2e-08 34.1 0.1 1.8 2 0 0 2 2 2 1 PX domain SH3_9 PF14604.6 KND99791.1 - 0.00067 19.5 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KND99791.1 - 0.0055 16.3 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Peptidase_M15_2 PF05951.13 KND99791.1 - 0.36 10.5 1.3 5.9 6.5 0.2 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF882) DUF2332 PF10094.9 KND99792.1 - 0.034 13.6 0.1 0.041 13.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2332) SH3_1 PF00018.28 KND99793.1 - 3.3e-12 45.8 0.0 9e-12 44.4 0.0 1.8 1 0 0 1 1 1 1 SH3 domain PX PF00787.24 KND99793.1 - 1.1e-09 38.3 0.3 2.9e-09 36.9 0.3 1.7 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 KND99793.1 - 5.5e-06 26.0 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KND99793.1 - 7.1e-06 25.8 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3367 PF11847.8 KND99793.1 - 0.074 10.9 0.0 0.1 10.5 0.0 1.1 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase Zn_clus PF00172.18 KND99796.1 - 3.3e-07 30.3 10.6 5.7e-07 29.6 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RSN1_7TM PF02714.15 KND99798.1 - 3.9e-79 265.8 31.5 8e-79 264.8 31.5 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KND99798.1 - 8.5e-31 106.8 4.7 8.5e-31 106.8 4.7 2.6 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KND99798.1 - 3.1e-19 69.9 0.0 4.6e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter zf-RanBP PF00641.18 KND99800.1 - 1.4e-12 46.7 14.8 2.4e-09 36.3 0.8 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 KND99800.1 - 4.6e-05 23.2 0.0 0.00016 21.4 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 KND99800.1 - 2.2 8.2 16.1 3.3 7.6 16.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glycos_transf_2 PF00535.26 KND99801.1 - 2.8e-35 121.6 0.0 3.4e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KND99801.1 - 3.8e-13 49.8 0.0 4.8e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KND99801.1 - 0.0002 20.9 0.0 0.00028 20.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KND99801.1 - 0.0004 19.9 0.0 0.00085 18.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 21 ThiF PF00899.21 KND99802.1 - 1.2e-61 208.2 0.0 1.7e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 KND99802.1 - 1.7e-06 28.2 9.6 3.5e-05 23.8 0.2 2.9 2 1 1 3 3 3 2 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.20 KND99802.1 - 0.0025 17.9 0.0 0.0059 16.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KND99802.1 - 0.077 13.6 0.1 2 9.0 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HEPN_Apea PF18739.1 KND99802.1 - 0.24 11.8 1.0 1.3 9.5 0.1 2.3 2 0 0 2 2 2 0 Apea-like HEPN Sacchrp_dh_NADP PF03435.18 KND99802.1 - 0.3 11.3 1.1 4.3 7.6 0.0 2.8 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Profilin PF00235.19 KND99803.1 - 4.7e-47 159.4 0.2 5.2e-47 159.3 0.2 1.0 1 0 0 1 1 1 1 Profilin BPTA PF17044.5 KND99805.1 - 0.014 15.2 0.0 0.019 14.9 0.0 1.1 1 0 0 1 1 1 0 Borrelial persistence in ticks protein A ArfGap PF01412.18 KND99808.1 - 1.2e-27 96.3 0.1 3e-27 95.0 0.0 1.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf UBA PF00627.31 KND99808.1 - 0.0034 17.2 0.0 0.0082 16.0 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain DUF3585 PF12130.8 KND99808.1 - 0.78 9.9 0.0 0.78 9.9 0.0 2.0 2 0 0 2 2 2 0 Bivalent Mical/EHBP Rab binding domain HVSL PF09749.9 KND99809.1 - 0.0097 15.4 0.2 0.015 14.8 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein Sugar_tr PF00083.24 KND99810.1 - 2.9e-115 385.7 22.5 3.5e-115 385.4 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND99810.1 - 8.2e-25 87.5 28.4 8.2e-25 87.5 28.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily GMC_oxred_N PF00732.19 KND99811.1 - 1.3e-57 195.4 0.2 2e-57 194.9 0.2 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KND99811.1 - 5.1e-25 88.7 0.3 7.8e-24 84.8 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KND99811.1 - 4.5e-09 35.9 1.7 3.3e-08 33.1 1.6 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KND99811.1 - 0.00082 18.7 0.1 0.011 15.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KND99811.1 - 0.0012 19.0 0.5 0.0031 17.7 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KND99811.1 - 0.005 16.5 0.5 0.024 14.2 0.5 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KND99811.1 - 0.012 14.9 0.1 0.94 8.7 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Mss4 PF04421.13 KND99813.1 - 1.2e-15 57.3 0.0 1.7e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Mss4 protein APH PF01636.23 KND99814.1 - 1.9e-34 119.7 0.0 2.3e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KND99814.1 - 2e-07 30.7 0.0 2.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KND99814.1 - 9.5e-07 28.6 0.0 1.5e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 KND99814.1 - 0.001 18.0 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) LRR_4 PF12799.7 KND99815.1 - 0.27 11.7 12.2 0.1 13.0 2.5 4.3 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KND99815.1 - 0.3 11.3 3.8 28 5.1 0.4 3.9 3 0 0 3 3 3 0 Leucine Rich repeat Myticin-prepro PF10690.9 KND99816.1 - 0.032 14.5 0.2 0.036 14.3 0.2 1.1 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel EIN3 PF04873.13 KND99818.1 - 0.058 12.7 0.1 0.059 12.7 0.1 1.1 1 0 0 1 1 1 0 Ethylene insensitive 3 UPF0126 PF03458.13 KND99818.1 - 0.084 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 UPF0126 domain MelC1 PF06236.11 KND99818.1 - 0.11 12.6 0.0 2.8 8.1 0.0 2.1 1 1 1 2 2 2 0 Tyrosinase co-factor MelC1 Aminotran_1_2 PF00155.21 KND99819.1 - 6e-35 121.1 0.0 7.7e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II cNMP_binding PF00027.29 KND99820.1 - 2.3e-22 78.8 0.1 3.1e-11 43.2 0.0 4.7 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.22 KND99820.1 - 1.2e-20 74.6 0.3 3.5e-20 73.1 0.3 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase DEAD PF00270.29 KND99821.1 - 3.9e-05 23.5 0.0 0.00013 21.8 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase PIF1 PF05970.14 KND99822.1 - 2.4e-64 217.8 0.1 3.1e-50 171.4 0.1 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KND99822.1 - 4e-20 72.3 0.0 9.3e-20 71.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KND99822.1 - 1e-10 42.1 0.0 1.8e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KND99822.1 - 3.9e-06 26.4 0.2 0.0073 15.6 0.0 3.1 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KND99822.1 - 5.1e-06 26.1 0.0 1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KND99822.1 - 5.4e-06 26.7 0.2 2.2e-05 24.7 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KND99822.1 - 3.9e-05 24.1 0.0 8.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Herpes_Helicase PF02689.14 KND99822.1 - 0.00015 19.9 0.1 0.0015 16.6 0.0 2.0 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 KND99822.1 - 0.0012 18.6 0.0 0.004 16.9 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.14 KND99822.1 - 0.0018 18.2 0.2 0.0061 16.4 0.2 1.9 1 1 0 1 1 1 1 Helicase AAA_16 PF13191.6 KND99822.1 - 0.0026 18.1 0.0 0.0085 16.5 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KND99822.1 - 0.0029 17.5 0.1 0.0075 16.2 0.1 1.7 1 0 0 1 1 1 1 NACHT domain DEAD PF00270.29 KND99822.1 - 0.0063 16.3 0.6 2.7 7.7 0.1 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase UvrD-helicase PF00580.21 KND99822.1 - 0.02 14.5 0.3 0.02 14.5 0.3 1.8 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KND99822.1 - 0.02 14.6 0.8 0.78 9.4 0.3 2.8 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 KND99822.1 - 0.022 14.8 0.8 0.09 12.8 0.1 2.5 3 1 0 3 3 1 0 AAA domain NTPase_1 PF03266.15 KND99822.1 - 0.022 14.7 0.3 0.085 12.8 0.1 2.0 2 0 0 2 2 2 0 NTPase RsgA_GTPase PF03193.16 KND99822.1 - 0.026 14.4 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 KND99822.1 - 0.028 14.9 0.6 0.11 13.0 0.3 2.0 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 KND99822.1 - 0.038 14.4 0.1 0.12 12.8 0.1 1.8 1 0 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.18 KND99822.1 - 0.047 13.0 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family PhoH PF02562.16 KND99822.1 - 0.049 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.22 KND99822.1 - 0.052 12.7 0.1 0.096 11.8 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain SH3_13 PF18335.1 KND99822.1 - 0.062 13.1 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain ATPase_2 PF01637.18 KND99822.1 - 0.065 13.1 1.1 0.5 10.2 1.1 2.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KND99822.1 - 0.13 11.9 0.1 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KND99822.1 - 0.33 10.0 1.2 0.74 8.8 1.2 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein DUF87 PF01935.17 KND99822.1 - 1.8 8.6 4.4 2.4 8.2 0.2 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain BNIP3 PF06553.12 KND99822.1 - 5.5 6.6 8.1 2 8.0 4.6 2.0 1 1 0 1 1 1 0 BNIP3 Sec39 PF08314.11 KND99823.1 - 3.9e-45 154.6 7.6 6.7e-45 153.8 7.6 1.3 1 1 0 1 1 1 1 Secretory pathway protein Sec39 Peptidase_M3_N PF08439.10 KND99823.1 - 0.035 14.4 1.1 17 5.7 0.1 3.4 2 0 0 2 2 2 0 Oligopeptidase F zf-C2H2_2 PF12756.7 KND99823.1 - 6.6 7.1 6.2 4.7 7.6 2.5 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) STAT_alpha PF01017.20 KND99824.1 - 0.011 15.7 3.4 0.015 15.2 1.4 2.1 2 0 0 2 2 2 0 STAT protein, all-alpha domain bZIP_1 PF00170.21 KND99824.1 - 0.04 14.0 0.2 0.04 14.0 0.2 3.2 3 0 0 3 3 3 0 bZIP transcription factor Bacillus_HBL PF05791.11 KND99824.1 - 0.042 13.7 1.3 0.28 11.0 1.0 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) ZapB PF06005.12 KND99824.1 - 0.056 13.9 6.7 0.11 12.9 0.1 3.6 4 0 0 4 4 4 0 Cell division protein ZapB DivIC PF04977.15 KND99824.1 - 0.089 12.6 0.5 0.089 12.6 0.5 3.2 3 1 0 3 3 3 0 Septum formation initiator Mit_KHE1 PF10173.9 KND99824.1 - 0.16 12.0 1.6 0.29 11.2 1.6 1.4 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Prominin PF05478.11 KND99824.1 - 0.19 9.7 1.5 0.29 9.1 1.5 1.2 1 0 0 1 1 1 0 Prominin Nup54 PF13874.6 KND99824.1 - 0.47 10.5 3.4 0.33 11.0 0.3 2.2 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 DivIVA PF05103.13 KND99824.1 - 0.64 10.1 9.5 2.2 8.4 0.3 3.7 3 1 0 4 4 4 0 DivIVA protein FapA PF03961.13 KND99824.1 - 3.3 6.2 6.7 0.95 8.0 2.5 2.0 1 1 0 2 2 2 0 Flagellar Assembly Protein A LSM PF01423.22 KND99825.1 - 1.6e-19 69.4 0.1 1.8e-19 69.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 KND99825.1 - 0.077 13.1 0.1 0.23 11.6 0.0 1.7 1 1 1 2 2 2 0 RimP C-terminal SH3 domain FAD_binding_8 PF08022.12 KND99826.1 - 5.3e-22 78.0 0.0 1.1e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KND99826.1 - 1.2e-21 77.5 0.0 1.9e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KND99826.1 - 1.2e-21 77.1 14.3 1.2e-21 77.1 14.3 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component TerC PF03741.16 KND99826.1 - 1.3 8.6 7.7 0.22 11.2 2.4 2.2 2 0 0 2 2 2 0 Integral membrane protein TerC family AIM5 PF17050.5 KND99828.1 - 2.2e-13 50.8 0.2 3.2e-13 50.3 0.2 1.3 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 adh_short PF00106.25 KND99830.1 - 1.7e-29 102.7 0.0 2.2e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND99830.1 - 5e-22 78.6 0.0 7e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND99830.1 - 3.6e-11 43.3 0.0 5.2e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 KR domain ApbA PF02558.16 KND99830.1 - 0.0025 17.5 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Epimerase PF01370.21 KND99830.1 - 0.0057 16.1 0.0 0.0095 15.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KND99830.1 - 0.017 14.4 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 KND99830.1 - 0.02 14.8 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KND99830.1 - 0.038 13.3 0.0 0.097 11.9 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3104 PF11302.8 KND99830.1 - 0.083 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Ribosomal_L17 PF01196.19 KND99831.1 - 4.8e-21 75.5 0.6 6.9e-21 75.0 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L17 Mrpl_C PF18502.1 KND99831.1 - 0.0043 17.3 0.1 0.011 16.0 0.0 1.7 2 0 0 2 2 2 1 54S ribosomal protein L8 C-terminal domain TMA7 PF09072.10 KND99832.1 - 1.5e-26 93.0 21.7 1.6e-26 92.9 21.7 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 LAP2alpha PF11560.8 KND99832.1 - 0.081 12.3 0.3 0.087 12.2 0.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 2 alpha cobW PF02492.19 KND99833.1 - 1.6e-49 167.9 9.1 5.9e-48 162.8 6.8 2.6 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KND99833.1 - 1.7e-19 69.5 0.0 5.8e-16 58.2 0.0 2.6 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain MeaB PF03308.16 KND99833.1 - 0.0012 17.9 0.2 1 8.3 0.0 2.6 2 1 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 KND99833.1 - 0.0037 16.8 3.6 0.57 9.7 0.9 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain CDC45 PF02724.14 KND99833.1 - 0.0053 15.1 5.0 0.0079 14.5 5.0 1.2 1 0 0 1 1 1 1 CDC45-like protein MobB PF03205.14 KND99833.1 - 0.0055 16.6 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF4637 PF15470.6 KND99833.1 - 0.012 15.3 0.9 0.022 14.5 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) TFIIA PF03153.13 KND99833.1 - 0.016 15.2 5.4 0.027 14.5 5.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_16 PF13191.6 KND99833.1 - 0.025 15.0 0.3 0.053 13.9 0.0 1.7 2 0 0 2 2 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KND99833.1 - 0.026 14.5 2.6 4.6 7.1 0.2 2.9 2 1 0 2 2 2 0 RsgA GTPase ATP_bind_1 PF03029.17 KND99833.1 - 0.033 14.0 0.1 1.7 8.3 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 KND99833.1 - 0.038 14.5 0.0 0.12 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 KND99833.1 - 0.049 13.5 0.1 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase TsaE PF02367.17 KND99833.1 - 0.051 13.6 0.2 0.1 12.6 0.2 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KND99833.1 - 0.072 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Astro_capsid_p PF12226.8 KND99833.1 - 0.1 11.7 6.9 0.17 11.0 6.9 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein T2SSE PF00437.20 KND99833.1 - 0.11 11.5 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 KND99833.1 - 0.18 11.6 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_pol_3_Rpc31 PF11705.8 KND99833.1 - 0.18 12.0 12.6 0.38 11.0 12.6 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 KND99833.1 - 0.29 9.3 11.5 0.44 8.7 11.5 1.2 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 KND99833.1 - 0.31 11.1 5.1 0.87 9.6 5.1 1.8 1 0 0 1 1 1 0 RXT2-like, N-terminal RRN3 PF05327.11 KND99833.1 - 0.37 9.3 5.4 0.61 8.6 5.4 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GEN1_C PF18380.1 KND99833.1 - 0.77 10.7 6.1 2.2 9.2 6.1 1.7 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain DUF2457 PF10446.9 KND99833.1 - 0.88 8.6 20.4 1.3 8.1 20.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAM176 PF14851.6 KND99833.1 - 3.4 7.3 7.1 3.5 7.3 5.8 1.7 2 0 0 2 2 1 0 FAM176 family Cnd2 PF05786.14 KND99833.1 - 3.9 6.0 10.0 6.1 5.4 10.0 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 SDA1 PF05285.12 KND99833.1 - 4 6.8 13.6 7.6 5.8 13.6 1.4 1 0 0 1 1 1 0 SDA1 GP67 PF17634.2 KND99833.1 - 4.2 7.9 22.0 1.3 9.4 18.6 2.0 2 0 0 2 2 1 0 Gene product 67 WH1 PF00568.23 KND99837.1 - 1.8e-30 105.2 0.0 3.4e-30 104.2 0.0 1.4 2 0 0 2 2 2 1 WH1 domain WH2 PF02205.20 KND99837.1 - 1.5e-06 27.8 0.9 3.6e-06 26.6 0.9 1.7 1 0 0 1 1 1 1 WH2 motif GCIP PF13324.6 KND99838.1 - 6.3e-17 62.0 2.3 9.1e-17 61.5 2.3 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Esterase PF00756.20 KND99839.1 - 1.4e-54 185.4 0.0 1.8e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KND99839.1 - 1.7e-07 31.0 0.1 3.1e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KND99839.1 - 0.00015 20.8 0.0 0.00043 19.3 0.0 1.7 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KND99839.1 - 0.00037 19.8 0.0 0.012 14.9 0.0 2.3 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KND99839.1 - 0.0012 17.9 0.1 0.61 9.0 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase AXE1 PF05448.12 KND99839.1 - 0.0045 15.7 0.0 0.0071 15.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 KND99839.1 - 0.0062 16.4 0.0 0.0086 15.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KND99839.1 - 0.011 15.4 0.6 0.06 13.0 0.3 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold Esterase_phd PF10503.9 KND99839.1 - 0.052 13.0 0.0 0.41 10.1 0.0 2.1 2 1 0 2 2 2 0 Esterase PHB depolymerase DUF915 PF06028.11 KND99839.1 - 0.086 12.2 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 KND99839.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) MFS_1 PF07690.16 KND99840.1 - 5.7e-30 104.4 43.5 6.5e-26 91.1 21.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND99840.1 - 2.1e-19 69.7 23.6 2.9e-18 66.0 23.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 KND99840.1 - 0.0004 19.4 4.3 0.0004 19.4 4.3 2.1 1 1 1 2 2 2 1 MFS_1 like family SNARE_assoc PF09335.11 KND99842.1 - 4.4e-17 62.7 4.7 9.9e-17 61.5 2.1 2.3 2 0 0 2 2 2 1 SNARE associated Golgi protein TctB PF07331.11 KND99842.1 - 0.00021 21.6 6.3 0.00021 21.6 6.3 1.8 2 1 0 2 2 2 1 Tripartite tricarboxylate transporter TctB family YqhR PF11085.8 KND99842.1 - 0.047 13.6 4.7 0.092 12.7 1.1 2.3 2 0 0 2 2 2 0 Conserved membrane protein YqhR T2SSM PF04612.12 KND99842.1 - 0.15 12.1 0.1 0.33 11.0 0.1 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M DUF2207 PF09972.9 KND99842.1 - 0.17 10.7 1.4 0.35 9.6 1.4 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TRIQK PF15168.6 KND99842.1 - 0.79 9.7 2.2 6.3 6.8 0.2 2.3 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family DUF2157 PF09925.9 KND99842.1 - 4.5 7.1 9.2 22 4.8 8.7 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) LIM PF00412.22 KND99843.1 - 5.6e-12 45.7 20.8 7.1e-08 32.6 6.8 2.7 2 0 0 2 2 2 2 LIM domain HTH_32 PF13565.6 KND99844.1 - 0.018 15.6 0.1 0.023 15.3 0.1 1.3 1 0 0 1 1 1 0 Homeodomain-like domain DUF550 PF04447.12 KND99844.1 - 0.073 13.2 0.0 0.087 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF550) PikAIV_N PF18605.1 KND99844.1 - 0.077 12.6 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Ribosomal_S11 PF00411.19 KND99846.1 - 0.079 13.4 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S11 CN_hydrolase PF00795.22 KND99846.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 1 0 1 1 1 0 Carbon-nitrogen hydrolase Pkinase PF00069.25 KND99848.1 - 5.2e-57 193.2 0.0 8.1e-57 192.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND99848.1 - 1.1e-27 97.0 0.0 1.6e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND99848.1 - 4.9e-05 22.8 0.0 7.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KND99848.1 - 0.00019 20.8 0.0 0.00031 20.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KND99848.1 - 0.026 13.5 0.2 0.041 12.8 0.2 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 KND99848.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KND99848.1 - 0.16 10.7 0.0 0.28 9.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase UPF0220 PF05255.11 KND99850.1 - 2.5e-71 238.6 4.9 2.9e-71 238.4 4.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF1689 PF07954.11 KND99850.1 - 0.14 12.6 0.9 1.6 9.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) WD40 PF00400.32 KND99851.1 - 3.5e-29 100.4 14.8 5.1e-06 27.1 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND99851.1 - 7.7e-20 71.0 0.8 0.00019 21.7 0.1 5.8 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KND99851.1 - 9.7e-08 31.1 4.5 0.0082 14.8 0.4 3.6 1 1 3 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 KND99851.1 - 5.8e-06 26.3 0.1 0.076 12.9 0.2 3.7 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KND99851.1 - 6e-06 25.8 3.3 0.0024 17.3 0.0 3.4 2 2 1 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 KND99851.1 - 1.5e-05 24.1 0.8 0.44 9.5 0.1 4.5 1 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KND99851.1 - 8.8e-05 21.4 1.1 0.11 11.2 0.1 3.4 1 1 2 3 3 3 2 Nup133 N terminal like Utp8 PF10395.9 KND99851.1 - 0.00039 19.1 0.5 0.45 8.9 0.1 2.3 1 1 0 2 2 2 2 Utp8 family Frtz PF11768.8 KND99851.1 - 0.0016 16.8 0.5 0.0056 15.1 0.1 1.9 2 1 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 KND99851.1 - 0.0075 15.2 1.7 0.077 11.9 0.0 2.8 1 1 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain USP7_C2 PF14533.6 KND99851.1 - 0.016 14.9 0.0 0.06 13.1 0.0 2.0 2 1 1 3 3 3 0 Ubiquitin-specific protease C-terminal PQQ_2 PF13360.6 KND99851.1 - 0.018 14.6 0.1 0.48 10.0 0.0 2.6 1 1 1 3 3 3 0 PQQ-like domain Pkinase PF00069.25 KND99852.1 - 2.5e-67 227.0 0.0 7.9e-67 225.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND99852.1 - 2.7e-42 144.8 0.0 4.1e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KND99852.1 - 1.9e-06 27.0 0.3 1.2e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KND99852.1 - 6.1e-05 22.5 0.0 0.00019 20.9 0.0 1.8 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KND99852.1 - 0.014 15.3 0.0 5 7.0 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KND99852.1 - 0.016 14.6 1.6 0.047 13.0 0.0 2.4 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAS_N PF17828.1 KND99852.1 - 0.13 12.2 0.5 0.78 9.7 0.3 2.2 2 1 0 2 2 2 0 N-terminal domain in fatty acid synthase subunit beta DUF4923 PF16270.5 KND99853.1 - 0.071 12.9 0.4 0.15 11.9 0.4 1.5 1 0 0 1 1 1 0 Lipocalin-like domain (DUF4923) Glycos_transf_4 PF00953.21 KND99853.1 - 0.1 12.6 0.7 0.16 11.9 0.7 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 4 CorA PF01544.18 KND99853.1 - 0.23 10.7 12.2 1.1 8.5 12.2 2.1 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein RhoGAP PF00620.27 KND99854.1 - 0.049 13.5 0.0 0.049 13.5 0.0 2.6 2 1 0 2 2 2 0 RhoGAP domain PPR_2 PF13041.6 KND99855.1 - 0.023 14.9 1.6 0.54 10.5 0.1 3.7 4 0 0 4 4 4 0 PPR repeat family PPR_3 PF13812.6 KND99855.1 - 6.2 7.0 5.7 84 3.4 0.5 3.7 1 1 1 2 2 2 0 Pentatricopeptide repeat domain eIF3_subunit PF08597.10 KND99856.1 - 7.7e-59 199.5 27.6 8.8e-59 199.3 27.6 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Peptidase_C58 PF03543.14 KND99856.1 - 4 7.1 8.2 0.6 9.8 3.8 1.8 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen SET PF00856.28 KND99857.1 - 5.3e-13 49.7 0.0 3e-12 47.3 0.0 2.1 2 0 0 2 2 2 1 SET domain ParB PF08775.10 KND99857.1 - 0.058 13.9 0.2 0.24 11.9 0.0 2.1 2 0 0 2 2 2 0 ParB family Thioredoxin PF00085.20 KND99858.1 - 1.4e-32 111.7 0.2 1.6e-32 111.5 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KND99858.1 - 1.9e-07 31.5 0.3 8.2e-07 29.4 0.3 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KND99858.1 - 3.7e-07 30.4 0.1 4.7e-05 23.6 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 KND99858.1 - 5.6e-07 29.4 0.0 5.9e-07 29.3 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.24 KND99858.1 - 6.6e-05 23.1 0.3 0.00023 21.3 0.1 1.9 1 1 1 2 2 2 1 Glutaredoxin Phosducin PF02114.16 KND99858.1 - 0.00019 20.5 0.0 0.00019 20.5 0.0 1.0 1 0 0 1 1 1 1 Phosducin DIM1 PF02966.16 KND99858.1 - 0.0003 20.6 0.0 0.00032 20.5 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Redoxin PF08534.10 KND99858.1 - 0.00034 20.3 0.3 0.0087 15.8 0.1 2.0 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.21 KND99858.1 - 0.00058 19.8 0.1 0.0043 16.9 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 KND99858.1 - 0.00088 18.7 0.0 0.00093 18.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HyaE PF07449.11 KND99858.1 - 0.0029 17.6 0.0 0.0044 17.0 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE TraF PF13728.6 KND99858.1 - 0.0034 17.3 0.1 0.004 17.0 0.1 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 KND99858.1 - 0.0062 16.7 0.1 0.02 15.1 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like Methyltransf_2 PF00891.18 KND99858.1 - 0.036 13.4 0.0 0.061 12.6 0.1 1.3 2 0 0 2 2 2 0 O-methyltransferase domain Thioredoxin_5 PF13743.6 KND99858.1 - 0.043 13.5 0.3 0.098 12.3 0.1 1.7 1 1 1 2 2 2 0 Thioredoxin PCYCGC PF13798.6 KND99858.1 - 0.14 12.0 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif Y_phosphatase PF00102.27 KND99859.1 - 3.8e-51 173.9 0.0 5.9e-51 173.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 KND99859.1 - 1.4e-06 28.8 0.0 4.9e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 KND99859.1 - 0.026 14.5 0.5 0.054 13.4 0.5 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family TRAPP PF04051.16 KND99864.1 - 1.7e-43 147.8 0.0 2.1e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Acetyltransf_1 PF00583.25 KND99865.1 - 1.6e-13 50.9 0.0 2.3e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KND99865.1 - 4.2e-07 30.0 0.1 5.4e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KND99865.1 - 8.8e-06 26.1 0.0 1.4e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KND99865.1 - 1.4e-05 24.9 0.0 2.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KND99865.1 - 0.00081 19.5 0.2 0.0021 18.1 0.2 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KND99865.1 - 0.0086 15.6 0.6 0.019 14.4 0.2 1.7 2 0 0 2 2 2 1 Putative acetyl-transferase Acetyltransf_3 PF13302.7 KND99865.1 - 0.078 13.6 0.0 0.16 12.6 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain KH_8 PF17903.1 KND99866.1 - 1.1e-06 28.7 0.0 2.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KND99866.1 - 0.057 13.2 0.3 0.13 12.1 0.3 1.6 1 0 0 1 1 1 0 KH domain MDM31_MDM32 PF08118.11 KND99868.1 - 2.2e-102 343.4 8.8 2.7e-68 231.0 9.5 2.2 1 1 1 2 2 2 2 Yeast mitochondrial distribution and morphology (MDM) proteins G-patch_2 PF12656.7 KND99869.1 - 1.2e-15 57.4 0.1 3e-15 56.0 0.1 1.7 1 0 0 1 1 1 1 G-patch domain SE PF08491.10 KND99869.1 - 0.096 11.7 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Squalene epoxidase AAA PF00004.29 KND99871.1 - 0.00019 21.8 0.0 0.00056 20.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KND99871.1 - 0.00079 19.4 0.1 0.95 9.4 0.0 3.3 2 1 1 3 3 3 2 Rad17 P-loop domain AAA_16 PF13191.6 KND99871.1 - 0.11 12.9 0.0 0.32 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KND99871.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TFIID-18kDa PF02269.16 KND99872.1 - 3.7e-32 110.2 3.3 5.2e-32 109.7 0.2 2.6 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit TAFII28 PF04719.14 KND99872.1 - 0.65 10.1 3.4 0.34 11.0 0.5 2.1 2 1 0 2 2 2 0 hTAFII28-like protein conserved region Syntaxin-6_N PF09177.11 KND99873.1 - 8.8e-12 45.4 7.1 3.8e-11 43.4 1.4 2.9 2 2 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KND99873.1 - 8.9e-09 35.2 1.3 2.1e-08 34.0 1.3 1.6 1 0 0 1 1 1 1 SNARE domain Laminin_II PF06009.12 KND99873.1 - 0.016 15.2 4.8 0.049 13.6 0.4 2.2 2 0 0 2 2 2 0 Laminin Domain II DUF16 PF01519.16 KND99873.1 - 0.027 15.0 3.6 0.027 15.0 3.6 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF1664 PF07889.12 KND99873.1 - 0.57 10.2 7.3 0.45 10.6 0.6 2.8 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DUF1732 PF08340.11 KND99873.1 - 1.5 8.9 6.5 0.15 12.1 0.8 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1732) BST2 PF16716.5 KND99873.1 - 2.5 8.8 11.1 0.49 11.0 1.4 2.8 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 Dpy-30 PF05186.13 KND99874.1 - 1.5e-12 47.0 0.0 9.1e-12 44.5 0.0 2.0 2 0 0 2 2 2 1 Dpy-30 motif Mito_carr PF00153.27 KND99875.1 - 2.1e-10 40.4 0.8 0.0013 18.6 0.0 3.7 3 1 0 3 3 3 2 Mitochondrial carrier protein Vps5 PF09325.10 KND99876.1 - 5e-06 26.2 11.5 1.2e-05 25.0 11.5 1.6 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KND99876.1 - 0.00084 19.3 2.5 0.0009 19.2 0.1 2.3 3 0 0 3 3 3 1 PX domain Prok-TraM PF09228.10 KND99876.1 - 0.0095 16.3 0.9 0.038 14.4 0.7 2.2 1 1 0 1 1 1 1 Prokaryotic Transcriptional repressor TraM Sod_Fe_C PF02777.18 KND99877.1 - 1e-32 112.3 0.8 2.2e-32 111.3 0.8 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KND99877.1 - 1e-28 99.6 0.8 2.1e-28 98.6 0.8 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Snf7 PF03357.21 KND99878.1 - 1.4e-09 37.8 17.8 2e-09 37.3 17.9 1.3 1 1 0 1 1 1 1 Snf7 FKBP_C PF00254.28 KND99878.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase BORCS7 PF16088.5 KND99878.1 - 0.32 11.3 5.5 0.15 12.3 1.2 2.4 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 7 DUF948 PF06103.11 KND99878.1 - 0.87 9.9 5.4 0.47 10.7 1.6 2.5 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TPR_1 PF00515.28 KND99879.1 - 1.1e-06 28.2 2.3 0.0099 15.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KND99879.1 - 7.8e-06 25.6 1.1 0.82 9.9 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KND99879.1 - 0.0035 17.6 2.7 0.068 13.5 0.1 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KND99879.1 - 0.0063 16.2 0.4 4.1 7.2 0.1 3.0 1 1 1 2 2 2 2 TPR repeat TPR_9 PF13371.6 KND99879.1 - 0.027 14.6 0.0 0.07 13.3 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat MIT PF04212.18 KND99879.1 - 0.078 13.1 0.5 9.8 6.3 0.0 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 KND99879.1 - 0.22 11.8 1.4 4.5 7.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Cid2 PF09774.9 KND99880.1 - 1e-30 107.3 7.2 4.1e-30 105.3 7.2 1.7 1 1 0 1 1 1 1 Caffeine-induced death protein 2 Pkinase PF00069.25 KND99881.1 - 5.9e-61 206.1 0.0 1.1e-60 205.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND99881.1 - 4.9e-29 101.4 0.0 2.8e-28 98.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND99881.1 - 6.2e-05 22.5 0.0 0.00055 19.3 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KND99881.1 - 0.025 13.5 1.3 0.037 13.0 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 KND99881.1 - 0.17 11.3 0.1 0.45 9.8 0.0 1.6 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M3 PF01432.20 KND99882.1 - 1.6e-109 367.2 1.4 2.1e-109 366.8 1.4 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KND99882.1 - 0.042 13.5 0.1 0.074 12.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like tRNA-synt_2b PF00587.25 KND99884.1 - 3.5e-26 92.3 0.0 6.3e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KND99884.1 - 1.1e-06 28.8 1.5 1.4e-06 28.4 0.6 1.6 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain APAF1_C PF17908.1 KND99885.1 - 0.018 15.0 0.1 0.018 15.0 0.1 2.3 2 1 0 2 2 2 0 APAF-1 helical domain CENP-T_C PF15511.6 KND99885.1 - 0.032 14.4 1.3 0.94 9.6 0.1 2.6 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold CENP-Q PF13094.6 KND99885.1 - 0.3 11.3 13.6 0.19 11.9 2.3 2.6 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ECH_2 PF16113.5 KND99885.1 - 0.34 10.3 4.5 0.81 9.1 2.7 2.1 1 1 1 2 2 2 0 Enoyl-CoA hydratase/isomerase SF-assemblin PF06705.11 KND99885.1 - 1.6 8.0 15.4 0.043 13.2 4.9 2.7 2 1 1 3 3 3 0 SF-assemblin/beta giardin Lgl_C PF08596.10 KND99887.1 - 9.4e-104 347.2 0.0 1.6e-102 343.2 0.0 2.1 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 KND99887.1 - 1.3e-10 41.4 0.9 0.13 12.6 0.0 6.7 6 2 2 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KND99887.1 - 6e-05 23.7 1.3 3 8.9 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat DPM2 PF07297.12 KND99889.1 - 4.1e-27 94.3 2.7 4.8e-27 94.1 2.7 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 KND99889.1 - 0.0034 17.3 0.6 0.0037 17.2 0.6 1.1 1 0 0 1 1 1 1 PIG-P Colicin_V PF02674.16 KND99889.1 - 0.0059 16.6 0.3 0.0066 16.4 0.3 1.2 1 0 0 1 1 1 1 Colicin V production protein O-ag_pol_Wzy PF14296.6 KND99889.1 - 0.027 13.1 0.2 0.03 13.0 0.2 1.0 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy Adap_comp_sub PF00928.21 KND99890.1 - 5e-40 137.5 0.0 1e-32 113.6 0.0 2.1 2 0 0 2 2 2 2 Adaptor complexes medium subunit family Cu-oxidase_2 PF07731.14 KND99891.1 - 1.5e-47 160.8 3.3 4.3e-41 139.9 0.3 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KND99891.1 - 1.9e-44 150.5 2.3 1.6e-40 137.8 0.2 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KND99891.1 - 3.8e-35 121.4 2.6 4.1e-28 98.5 0.2 3.3 3 0 0 3 3 3 3 Multicopper oxidase Cupredoxin_1 PF13473.6 KND99891.1 - 0.013 15.6 0.0 0.77 9.9 0.0 3.2 2 1 0 2 2 2 0 Cupredoxin-like domain C1q PF00386.21 KND99891.1 - 0.042 14.0 0.1 0.22 11.7 0.0 2.1 2 0 0 2 2 2 0 C1q domain KH_dom-like PF14714.6 KND99892.1 - 0.064 13.6 0.0 0.064 13.6 0.0 1.1 1 0 0 1 1 1 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Abhydrolase_6 PF12697.7 KND99894.1 - 1.3e-13 52.1 0.2 1.9e-13 51.6 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KND99894.1 - 1.6e-13 50.9 0.0 3.1e-13 50.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KND99894.1 - 0.0002 20.7 0.0 0.00048 19.5 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KND99894.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase ThiF PF00899.21 KND99896.1 - 4.1e-63 213.0 0.0 5.8e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KND99896.1 - 1.5e-22 79.5 0.0 2.8e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 KND99896.1 - 0.00011 22.3 0.5 0.00064 19.8 0.0 2.3 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase DNA_ligase_ZBD PF03119.16 KND99896.1 - 0.055 13.5 0.3 0.14 12.2 0.3 1.7 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain NAD_binding_7 PF13241.6 KND99896.1 - 0.059 13.8 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 KND99896.1 - 0.081 13.5 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PglD_N PF17836.1 KND99896.1 - 0.15 12.8 3.5 0.29 11.8 0.3 2.7 3 0 0 3 3 3 0 PglD N-terminal domain Ecm33 PF12454.8 KND99896.1 - 0.17 12.1 0.8 0.34 11.1 0.8 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Rad52_Rad22 PF04098.15 KND99897.1 - 1.3e-56 190.7 0.0 2.7e-56 189.8 0.0 1.5 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein BLM10_N PF16547.5 KND99897.1 - 0.28 11.5 3.7 1.4 9.3 0.1 2.6 2 0 0 2 2 2 0 Proteasome-substrate-size regulator, N-terminal Tropomodulin PF03250.14 KND99898.1 - 0.13 12.3 3.8 0.17 11.9 3.8 1.1 1 0 0 1 1 1 0 Tropomodulin DUF4986 PF16375.5 KND99898.1 - 0.22 12.2 1.7 3 8.6 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function LSM PF01423.22 KND99899.1 - 1.7e-14 53.2 0.1 2e-14 53.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KND99899.1 - 0.0079 15.8 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Hfq protein HECT PF00632.25 KND99900.1 - 6.7e-95 318.1 0.0 1.8e-94 316.7 0.0 1.8 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 KND99900.1 - 4e-65 220.6 1.8 2.9e-64 217.7 1.8 2.5 1 1 0 1 1 1 1 Domain of Unknown Function (DUF908) DUF913 PF06025.12 KND99900.1 - 2.1e-47 161.9 0.0 2.1e-47 161.9 0.0 3.6 3 1 0 3 3 3 1 Domain of Unknown Function (DUF913) UBM PF14377.6 KND99900.1 - 4.5e-18 64.0 9.3 1.3e-09 37.2 0.8 2.7 2 0 0 2 2 2 2 Ubiquitin binding region Phage_Gp23 PF10669.9 KND99900.1 - 0.35 11.2 10.9 1.8 8.9 10.9 2.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) 4HBT_2 PF13279.6 KND99901.1 - 2e-09 38.0 0.1 3e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily ELO PF01151.18 KND99905.1 - 7.3e-60 202.6 24.0 9.4e-60 202.2 24.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CNH PF00780.22 KND99907.1 - 2.5e-70 237.2 0.0 7.6e-70 235.6 0.0 1.8 2 0 0 2 2 2 1 CNH domain RhoGEF PF00621.20 KND99907.1 - 7.5e-40 137.1 1.8 8.1e-40 137.0 0.2 1.9 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.6 KND99907.1 - 3.9e-24 85.3 0.3 7.8e-24 84.3 0.3 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 KND99907.1 - 6.2e-14 51.8 0.0 1.3e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) NuA4 PF09340.10 KND99908.1 - 0.089 12.7 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 P21-Arc PF04062.14 KND99910.1 - 1.6e-75 252.9 0.0 1.8e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Metallophos PF00149.28 KND99911.1 - 1.3e-09 38.9 3.6 1.3e-09 38.9 3.6 3.1 3 1 0 4 4 4 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KND99911.1 - 0.065 13.4 0.0 9.8 6.3 0.0 2.9 3 0 0 3 3 3 0 Calcineurin-like phosphoesterase superfamily domain RRM_1 PF00076.22 KND99912.1 - 2.9e-14 52.6 0.0 4.4e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 KND99913.1 - 1.8e-18 66.9 0.9 2.5e-18 66.4 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain FAD_binding_2 PF00890.24 KND99915.1 - 5.4e-123 411.1 2.6 6.8e-123 410.8 2.6 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KND99915.1 - 4.6e-45 152.7 0.7 7e-45 152.1 0.7 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 KND99915.1 - 2.9e-06 26.6 0.4 0.0012 18.0 0.7 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 KND99915.1 - 4.5e-06 26.1 0.2 0.0035 16.6 0.1 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 KND99915.1 - 2e-05 24.0 0.3 0.00014 21.2 0.1 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KND99915.1 - 0.003 16.9 0.1 0.0063 15.8 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KND99915.1 - 0.011 15.3 1.2 0.039 13.6 1.2 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KND99915.1 - 0.023 13.4 0.0 0.11 11.1 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein ATP-synt_D PF01813.17 KND99916.1 - 7.7e-71 238.0 4.6 1e-70 237.6 4.6 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Ribosomal_L6e PF01159.19 KND99916.1 - 1.8 9.1 6.4 0.3 11.7 1.2 2.2 2 1 0 2 2 2 0 Ribosomal protein L6e Trm112p PF03966.16 KND99917.1 - 3.3e-17 62.8 0.1 4.3e-17 62.4 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein ADK_lid PF05191.14 KND99917.1 - 0.029 14.4 0.6 0.062 13.3 0.6 1.5 1 0 0 1 1 1 0 Adenylate kinase, active site lid DUF2312 PF10073.9 KND99918.1 - 0.058 13.0 3.1 0.16 11.7 3.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) RTT107_BRCT_5 PF16770.5 KND99919.1 - 0.039 13.8 0.0 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain A2M PF00207.22 KND99919.1 - 0.06 13.2 0.3 0.58 10.0 0.1 2.2 2 0 0 2 2 2 0 Alpha-2-macroglobulin family Syja_N PF02383.18 KND99920.1 - 9.6e-47 159.8 0.1 2.1e-46 158.8 0.1 1.4 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 KND99920.1 - 3.2e-07 30.1 0.0 5.2e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Sugar_tr PF00083.24 KND99922.1 - 5.4e-52 177.2 27.7 5.1e-51 173.9 27.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND99922.1 - 1.6e-19 70.0 33.2 9.9e-12 44.4 18.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 KND99922.1 - 0.00044 18.6 0.8 0.47 8.6 0.0 2.2 2 0 0 2 2 2 2 BT1 family MFS_3 PF05977.13 KND99922.1 - 0.0014 17.2 0.2 0.0014 17.2 0.2 2.5 2 1 0 2 2 2 1 Transmembrane secretion effector MFS_2 PF13347.6 KND99922.1 - 0.0019 16.9 17.4 0.014 14.0 5.2 3.2 3 1 0 3 3 3 3 MFS/sugar transport protein DMT_YdcZ PF04657.13 KND99922.1 - 0.0096 16.2 14.9 0.0097 16.2 0.5 3.7 2 2 1 3 3 3 2 Putative inner membrane exporter, YdcZ RSN1_7TM PF02714.15 KND99924.1 - 6.1e-77 258.6 24.5 6.1e-77 258.6 24.5 2.0 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KND99924.1 - 2.8e-42 144.1 2.4 2.8e-42 144.1 2.4 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KND99924.1 - 1e-26 94.3 0.1 2.9e-26 92.8 0.1 1.8 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KND99924.1 - 1.4e-21 76.4 0.1 3.7e-21 75.1 0.1 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RCR PF12273.8 KND99925.1 - 4.9e-34 117.5 7.1 1.3e-33 116.1 6.2 1.8 1 1 1 2 2 2 1 Chitin synthesis regulation, resistance to Congo red DUF2167 PF09935.9 KND99925.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) TP6A_N PF04406.14 KND99926.1 - 2.5e-07 30.6 0.1 5.2e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Pyrophosphatase PF00719.19 KND99927.1 - 9.8e-59 197.7 0.1 1.4e-58 197.2 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Rad51 PF08423.11 KND99929.1 - 1.7e-16 60.2 0.2 6.3e-15 55.1 0.2 2.2 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 KND99929.1 - 1.4e-05 24.5 0.0 3.1e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 KaiC AAA_22 PF13401.6 KND99929.1 - 0.042 14.1 0.1 0.13 12.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain RecA PF00154.21 KND99929.1 - 0.049 13.1 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Viral_helicase1 PF01443.18 KND99929.1 - 0.07 12.9 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Dynactin_p22 PF07426.11 KND99929.1 - 0.17 11.7 0.6 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Dynactin subunit p22 Maf1 PF09174.10 KND99930.1 - 4.2e-09 36.8 0.2 6.9e-09 36.1 0.2 1.4 1 0 0 1 1 1 1 Maf1 regulator SET PF00856.28 KND99934.1 - 1.4e-10 41.8 0.0 3.5e-10 40.5 0.0 1.7 1 1 0 1 1 1 1 SET domain NPV_P10 PF05531.12 KND99934.1 - 0.12 12.9 0.1 0.3 11.6 0.0 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Myticin-prepro PF10690.9 KND99934.1 - 1.3 9.3 4.3 15 5.9 0.4 2.5 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel 5-FTHF_cyc-lig PF01812.20 KND99935.1 - 2.4e-39 135.2 0.0 2.6e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Cyt-b5 PF00173.28 KND99936.1 - 1.3e-24 86.1 0.0 1.7e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain UCH PF00443.29 KND99937.1 - 5.9e-23 81.7 11.1 2.4e-21 76.4 9.2 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Rota_NS6 PF04866.12 KND99937.1 - 0.077 13.2 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 Rotavirus non-structural protein 6 DUF883 PF05957.13 KND99937.1 - 0.11 13.1 0.2 4.4 8.0 0.0 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) SPX PF03105.19 KND99938.1 - 4.8e-41 142.0 6.2 8.9e-26 91.7 2.9 2.2 1 1 1 2 2 2 2 SPX domain CitMHS PF03600.16 KND99938.1 - 7.3e-26 91.1 61.7 1.1e-22 80.6 38.9 2.1 1 1 1 2 2 2 2 Citrate transporter Na_sulph_symp PF00939.19 KND99938.1 - 2.1e-20 73.3 38.6 3.1e-20 72.7 38.6 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region TMEM208_SND2 PF05620.11 KND99940.1 - 4.9e-42 143.5 2.1 5.3e-42 143.4 2.1 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 PEMT PF04191.13 KND99940.1 - 2.8e-05 24.5 0.7 4.7e-05 23.7 0.7 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase BolA PF01722.18 KND99941.1 - 1e-27 96.2 2.0 1.4e-27 95.8 2.0 1.1 1 0 0 1 1 1 1 BolA-like protein Myosin_head PF00063.21 KND99942.1 - 7.9e-234 777.9 7.8 7.9e-234 777.9 7.8 1.8 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.19 KND99942.1 - 5.2e-26 91.0 1.0 5.2e-26 91.0 1.0 3.1 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 KND99942.1 - 3e-12 45.2 24.7 4.5e-05 22.9 0.1 6.8 6 0 0 6 6 6 4 IQ calmodulin-binding motif KASH_CCD PF14662.6 KND99942.1 - 0.0019 18.1 20.7 0.0088 15.9 20.7 2.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH AAA_22 PF13401.6 KND99942.1 - 0.0057 16.9 1.6 0.04 14.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain Ntox35 PF15534.6 KND99942.1 - 0.013 15.9 0.0 0.057 13.9 0.0 2.1 1 0 0 1 1 1 0 Bacterial toxin 35 AAA_16 PF13191.6 KND99942.1 - 0.1 13.0 0.7 0.68 10.3 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 KND99942.1 - 0.12 12.8 1.7 1.3 9.4 0.0 3.2 3 0 0 3 3 2 0 RNA helicase T6PP_N PF18572.1 KND99942.1 - 0.18 11.7 9.8 0.4 10.5 0.0 4.0 2 1 0 2 2 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain ABC_tran PF00005.27 KND99942.1 - 0.24 11.9 0.1 0.24 11.9 0.1 3.1 3 1 0 3 3 1 0 ABC transporter Peptidase_M75 PF09375.10 KND99942.1 - 1 8.8 9.1 2 7.8 9.1 1.5 1 0 0 1 1 1 0 Imelysin Tup_N PF08581.10 KND99942.1 - 1.3 9.3 15.5 4.8 7.6 5.7 4.5 2 1 1 4 4 4 0 Tup N-terminal YabA PF06156.13 KND99942.1 - 6.1 7.5 14.9 5.5 7.7 2.4 3.8 1 1 1 2 2 2 0 Initiation control protein YabA FMN_dh PF01070.18 KND99943.1 - 1.8e-114 382.4 0.0 2.2e-114 382.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KND99943.1 - 9.4e-25 86.6 0.2 2.1e-24 85.4 0.2 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KND99943.1 - 3.3e-08 33.1 0.1 5.3e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KND99943.1 - 0.00075 18.6 0.9 0.0018 17.4 0.4 1.7 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain InvH PF04741.12 KND99944.1 - 0.059 13.3 0.2 0.18 11.7 0.2 1.8 1 0 0 1 1 1 0 InvH outer membrane lipoprotein DUF1837 PF08878.11 KND99944.1 - 0.071 12.9 0.4 0.11 12.3 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1837) Ran-binding PF05508.11 KND99945.1 - 1.9e-76 257.1 2.1 2.9e-76 256.4 2.1 1.3 1 0 0 1 1 1 1 RanGTP-binding protein FlxA PF14282.6 KND99945.1 - 0.022 14.7 1.1 0.022 14.7 1.1 2.0 2 0 0 2 2 2 0 FlxA-like protein DUF948 PF06103.11 KND99945.1 - 0.13 12.6 0.9 0.36 11.1 0.9 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) TBCA PF02970.16 KND99945.1 - 0.17 12.2 0.3 0.17 12.2 0.3 2.8 3 0 0 3 3 3 0 Tubulin binding cofactor A DUF2457 PF10446.9 KND99945.1 - 0.55 9.3 25.6 1.5 7.9 25.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 KND99945.1 - 5.8 4.9 28.6 0.52 8.3 23.7 1.7 2 0 0 2 2 2 0 DNA polymerase phi ABC_tran_CTD PF16326.5 KND99945.1 - 9.6 6.5 11.6 1.3 9.3 5.6 2.6 2 1 0 2 2 2 0 ABC transporter C-terminal domain SNF2_N PF00176.23 KND99946.1 - 2e-57 194.5 0.0 3.2e-57 193.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 KND99946.1 - 2.1e-39 135.5 0.2 3.7e-39 134.8 0.2 1.4 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 KND99946.1 - 1.6e-16 60.6 0.0 3.7e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KND99946.1 - 6.2e-07 28.9 0.1 3.8e-06 26.3 0.1 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KND99946.1 - 6.9e-06 26.2 0.0 1.6e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KND99946.1 - 1.4e-05 24.4 0.4 9.4e-05 21.7 0.1 2.0 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 KND99946.1 - 0.0037 17.5 0.0 0.12 12.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain FAD_binding_2 PF00890.24 KND99948.1 - 7.8e-77 259.1 0.0 1.4e-76 258.3 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain Cyt-b5 PF00173.28 KND99948.1 - 7.8e-22 77.2 0.0 3.6e-21 75.1 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KND99948.1 - 1.4e-12 47.9 0.1 3.7e-12 46.5 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KND99948.1 - 1.2e-07 31.5 0.1 1e-06 28.4 0.3 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KND99948.1 - 2.6e-07 30.8 0.8 1.1e-06 28.7 0.3 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KND99948.1 - 6.8e-07 28.8 0.7 2.5e-05 23.7 0.3 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KND99948.1 - 1.4e-05 24.0 0.4 0.0055 15.4 0.1 2.8 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 KND99948.1 - 0.00039 19.6 2.2 0.0036 16.5 0.0 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KND99948.1 - 0.002 17.4 0.3 0.0034 16.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KND99948.1 - 0.0032 16.8 0.0 0.006 15.9 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KND99948.1 - 0.091 12.0 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Actin PF00022.19 KND99949.1 - 3.9e-143 476.9 0.0 1.3e-142 475.3 0.0 1.7 1 1 0 1 1 1 1 Actin GerD PF17898.1 KND99949.1 - 0.14 12.1 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 Spore germination GerD central core domain 3Beta_HSD PF01073.19 KND99953.1 - 1.3e-83 280.3 0.0 1.6e-83 280.0 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KND99953.1 - 4.1e-28 98.5 0.0 5.3e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KND99953.1 - 3.5e-20 72.7 0.0 9.8e-20 71.2 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KND99953.1 - 1.3e-14 54.0 0.0 8.9e-14 51.3 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 KND99953.1 - 1.4e-09 37.4 0.0 2.3e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KND99953.1 - 6.6e-08 32.7 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KND99953.1 - 3.9e-07 29.5 0.0 7.2e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KND99953.1 - 3.5e-05 23.8 0.0 0.00028 20.9 0.0 2.1 1 1 0 1 1 1 1 KR domain Mus7 PF09462.10 KND99957.1 - 1.7e-34 119.7 24.8 1.7e-27 96.6 5.5 2.8 2 1 1 3 3 3 2 Mus7/MMS22 family FliH PF02108.16 KND99957.1 - 0.0098 16.0 0.1 0.025 14.6 0.1 1.7 1 0 0 1 1 1 1 Flagellar assembly protein FliH SANT_DAMP1_like PF16282.5 KND99958.1 - 2.8e-17 62.7 4.1 1.5e-16 60.4 0.3 2.6 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 KND99958.1 - 0.00072 19.7 0.1 0.0026 18.0 0.1 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KND99958.1 - 0.076 13.2 0.9 0.17 12.1 0.1 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain AFG1_ATPase PF03969.16 KND99959.1 - 1.2e-72 244.8 0.0 2.1e-69 234.2 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KND99959.1 - 0.00026 21.4 0.2 0.88 9.9 0.2 2.6 1 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KND99959.1 - 0.043 14.1 0.0 0.12 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KND99959.1 - 0.043 14.2 0.0 0.089 13.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KND99959.1 - 0.045 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATG13 PF10033.9 KND99960.1 - 2.2e-68 230.5 0.1 1.7e-67 227.7 0.1 2.2 2 0 0 2 2 2 1 Autophagy-related protein 13 TPR_2 PF07719.17 KND99962.1 - 1.1e-27 93.8 40.5 5.4e-05 23.0 0.3 14.1 14 0 0 14 14 13 7 Tetratricopeptide repeat TPR_1 PF00515.28 KND99962.1 - 4e-27 92.9 37.5 8.7e-05 22.2 0.4 14.1 14 0 0 14 14 13 6 Tetratricopeptide repeat TPR_16 PF13432.6 KND99962.1 - 2.5e-24 85.6 23.9 5.3e-05 23.8 0.0 11.2 10 3 3 13 13 11 6 Tetratricopeptide repeat TPR_19 PF14559.6 KND99962.1 - 9e-24 83.8 30.7 9.4e-05 22.8 0.0 13.4 12 2 2 14 14 13 7 Tetratricopeptide repeat TPR_14 PF13428.6 KND99962.1 - 1.5e-22 78.3 32.7 0.0044 17.7 0.0 14.2 13 2 3 16 16 12 6 Tetratricopeptide repeat TPR_8 PF13181.6 KND99962.1 - 1.5e-21 74.7 28.8 0.00041 20.3 0.3 13.2 14 0 0 14 14 12 5 Tetratricopeptide repeat TPR_12 PF13424.6 KND99962.1 - 1e-16 61.0 28.1 0.49 10.7 0.2 11.6 9 2 3 12 12 12 7 Tetratricopeptide repeat TPR_11 PF13414.6 KND99962.1 - 1.7e-14 53.2 16.0 0.0025 17.4 0.1 10.2 10 2 2 12 12 10 3 TPR repeat TPR_17 PF13431.6 KND99962.1 - 3.7e-14 52.0 19.2 0.026 14.9 0.0 12.8 11 2 2 13 13 13 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KND99962.1 - 3.3e-13 49.7 10.6 0.026 14.7 0.0 8.6 7 3 1 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_22 PF18833.1 KND99962.1 - 2.2e-11 43.7 0.0 7.6e-11 42.0 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 KND99962.1 - 3.9e-11 42.8 25.1 0.16 12.7 0.1 12.9 15 0 0 15 15 11 2 Tetratricopeptide repeat TPR_9 PF13371.6 KND99962.1 - 4.4e-06 26.8 15.8 0.19 11.9 0.0 7.1 7 1 1 8 8 6 3 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KND99962.1 - 8.2e-06 25.5 0.7 0.021 14.5 0.2 4.8 4 1 0 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_7 PF13176.6 KND99962.1 - 1.3e-05 24.9 23.3 2.5 8.3 0.0 11.1 12 0 0 12 12 10 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KND99962.1 - 5.2e-05 23.2 1.7 0.55 10.4 0.0 5.0 4 0 0 4 4 3 1 Fis1 C-terminal tetratricopeptide repeat Sel1 PF08238.12 KND99962.1 - 0.00082 20.0 6.3 4.2 8.2 0.0 5.8 6 0 0 6 6 5 1 Sel1 repeat PknG_TPR PF16918.5 KND99962.1 - 0.025 13.3 2.1 3.3 6.4 0.0 3.5 4 0 0 4 4 4 0 Protein kinase G tetratricopeptide repeat VWA_2 PF13519.6 KND99962.1 - 0.037 14.7 0.2 1.6 9.4 0.0 3.9 4 1 0 4 4 3 0 von Willebrand factor type A domain ANAPC5 PF12862.7 KND99962.1 - 0.67 10.1 7.0 24 5.1 0.0 5.2 7 0 0 7 7 4 0 Anaphase-promoting complex subunit 5 SHNi-TPR PF10516.9 KND99962.1 - 1.7 8.1 9.3 4.7 6.7 0.1 4.0 5 0 0 5 5 5 0 SHNi-TPR TPR_4 PF07721.14 KND99962.1 - 3.1 8.7 14.0 44 5.1 0.0 6.1 5 0 0 5 5 4 0 Tetratricopeptide repeat RNA_pol_Rpc82 PF05645.13 KND99963.1 - 4.6e-53 180.6 0.1 4.6e-53 180.6 0.1 2.3 2 1 1 3 3 3 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 KND99963.1 - 4.4e-17 61.9 13.0 8.8e-17 61.0 0.3 4.2 5 0 0 5 5 5 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KND99963.1 - 1.6e-05 24.7 1.0 0.075 12.9 0.4 3.2 3 0 0 3 3 3 2 TFIIE alpha subunit SMC_ScpB PF04079.16 KND99963.1 - 0.013 15.1 0.5 0.44 10.1 0.0 2.5 2 0 0 2 2 2 0 Segregation and condensation complex subunit ScpB MIP PF00230.20 KND99964.1 - 7.1e-42 143.7 17.0 8.8e-42 143.3 17.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein Hexapep_loop PF18776.1 KND99964.1 - 0.39 10.4 2.0 0.89 9.2 0.0 2.5 2 0 0 2 2 2 0 Hexapeptide repeat including loop PRA1 PF03208.19 KND99964.1 - 0.96 9.1 4.6 2.8 7.6 4.5 1.9 1 1 0 1 1 1 0 PRA1 family protein Ribosomal_60s PF00428.19 KND99967.1 - 1 10.0 12.3 1.4 9.5 12.3 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein RNA_pol_Rpc4 PF05132.14 KND99968.1 - 0.12 12.8 2.7 0.17 12.3 2.7 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Mito_carr PF00153.27 KND99970.1 - 4.3e-36 122.7 10.5 8.6e-14 51.2 0.2 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein TnpV PF14198.6 KND99971.1 - 0.017 15.1 2.1 0.04 13.9 1.0 2.2 2 0 0 2 2 2 0 Transposon-encoded protein TnpV DUF592 PF04574.13 KND99971.1 - 0.018 14.8 0.1 0.055 13.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF592) DUF3164 PF11363.8 KND99971.1 - 0.031 13.9 0.2 0.072 12.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3164) CDC50 PF03381.15 KND99972.1 - 6.1e-94 314.7 0.2 7.9e-94 314.3 0.2 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Plant_vir_prot PF01307.17 KND99972.1 - 0.01 16.0 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 Plant viral movement protein DUF202 PF02656.15 KND99972.1 - 0.31 11.5 0.8 15 6.1 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) CAF1 PF04857.20 KND99973.1 - 8.7e-05 21.8 7.2 0.0039 16.4 0.0 2.7 2 1 0 3 3 3 2 CAF1 family ribonuclease DUF4820 PF16091.5 KND99974.1 - 0.58 9.5 4.8 0.7 9.2 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) NGP1NT PF08153.12 KND99975.1 - 2.5e-50 170.0 0.5 3.9e-50 169.3 0.5 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KND99975.1 - 0.044 13.9 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF3818 PF12825.7 KND99976.1 - 2.1e-86 290.0 16.4 2.1e-86 290.0 16.4 2.0 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KND99976.1 - 1.2e-26 93.2 0.9 1.2e-26 93.2 0.9 2.1 2 0 0 2 2 2 1 PX-associated PX PF00787.24 KND99976.1 - 6.4e-07 29.3 0.3 6.4e-07 29.3 0.3 3.8 4 0 0 4 4 4 1 PX domain UPF0149 PF03695.13 KND99976.1 - 0.017 15.4 0.3 0.26 11.6 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) LicD PF04991.13 KND99977.1 - 8e-22 78.5 26.2 2.1e-20 73.8 0.3 5.0 3 2 2 5 5 5 3 LicD family HlyIII PF03006.20 KND99978.1 - 4e-48 164.1 13.3 5.6e-48 163.6 13.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related AP3D1 PF06375.11 KND99979.1 - 0.0026 18.0 4.2 0.0036 17.5 4.2 1.1 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 Agouti PF05039.12 KND99979.1 - 0.11 13.3 1.9 0.14 12.9 1.9 1.2 1 0 0 1 1 1 0 Agouti protein Sugar_tr PF00083.24 KND99982.1 - 1.3e-112 377.0 19.1 1.5e-112 376.8 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND99982.1 - 1e-20 74.0 31.0 3.6e-16 59.0 5.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OppC_N PF12911.7 KND99982.1 - 0.84 9.7 5.0 0.75 9.8 0.1 3.2 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Zn_clus PF00172.18 KND99984.1 - 1.8e-08 34.3 8.7 4.4e-08 33.1 8.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND99984.1 - 2.6e-05 23.4 1.6 6.9e-05 22.0 1.6 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-PHD-like PF15446.6 KND99984.1 - 0.00089 18.9 2.4 0.0016 18.1 2.4 1.3 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain Sybindin PF04099.12 KND99988.1 - 1.8e-33 115.5 1.0 4.9e-32 110.8 1.0 2.1 1 1 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KND99988.1 - 1.4e-08 34.9 0.1 1.7e-08 34.6 0.1 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Methyltransf_23 PF13489.6 KND99990.1 - 1.6e-16 60.5 0.0 2.2e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND99990.1 - 1.1e-14 55.0 0.2 4.7e-14 52.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND99990.1 - 6.7e-13 49.2 0.0 1.5e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND99990.1 - 7.1e-11 42.6 0.0 1.3e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND99990.1 - 2.3e-08 34.0 0.0 4.8e-08 33.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KND99990.1 - 0.00044 19.7 0.0 0.00068 19.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 KND99990.1 - 0.0037 16.5 0.0 1.6 7.8 0.0 2.1 2 0 0 2 2 2 2 NNMT/PNMT/TEMT family TehB PF03848.14 KND99990.1 - 0.011 15.1 0.1 0.11 11.9 0.0 2.4 2 1 0 2 2 2 0 Tellurite resistance protein TehB MTS PF05175.14 KND99990.1 - 0.043 13.4 0.0 0.12 11.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain MdoG PF04349.12 KND99990.1 - 0.045 12.7 0.0 0.063 12.2 0.0 1.1 1 0 0 1 1 1 0 Periplasmic glucan biosynthesis protein, MdoG APG5 PF04106.12 KND99991.1 - 1.8e-44 152.0 0.4 2.2e-44 151.8 0.4 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 YjeF_N PF03853.15 KND99995.1 - 1.7e-36 125.7 0.0 2.1e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus DUF429 PF04250.13 KND99995.1 - 0.18 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF429) Septin PF00735.18 KND99997.1 - 2.5e-90 302.6 0.3 6.5e-90 301.2 0.3 1.7 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KND99997.1 - 6.9e-06 26.1 0.2 4e-05 23.7 0.1 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KND99997.1 - 2e-05 24.2 0.1 0.00017 21.2 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 KND99997.1 - 0.0016 18.2 0.0 0.0058 16.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain Synaptobrevin PF00957.21 KND99997.1 - 0.0031 17.3 1.2 0.0074 16.1 1.2 1.6 1 0 0 1 1 1 1 Synaptobrevin AAA_22 PF13401.6 KND99997.1 - 0.01 16.1 0.0 0.059 13.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KND99997.1 - 0.01 16.2 0.3 0.14 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 KND99997.1 - 0.015 15.2 3.2 0.037 13.9 0.0 2.6 2 1 0 2 2 2 0 RsgA GTPase AAA_19 PF13245.6 KND99997.1 - 0.019 15.3 0.5 0.082 13.2 0.0 2.3 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 KND99997.1 - 0.04 13.0 0.0 0.1 11.7 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.6 KND99997.1 - 0.054 13.3 9.3 0.12 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KND99997.1 - 0.063 13.3 2.3 13 5.8 0.0 3.3 3 0 0 3 3 3 0 Dynamin family FtsK_SpoIIIE PF01580.18 KND99997.1 - 0.065 12.6 0.3 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family FeoB_N PF02421.18 KND99997.1 - 0.098 12.2 0.2 0.27 10.7 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.29 KND99997.1 - 0.098 13.1 0.0 0.3 11.5 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4570 PF15134.6 KND99997.1 - 0.56 10.2 7.2 1.4 8.9 5.6 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4570) DUF87 PF01935.17 KND99997.1 - 2.9 7.9 7.8 2 8.4 0.0 2.8 2 1 0 2 2 2 0 Helicase HerA, central domain HEAT PF02985.22 KND99999.1 - 3.6e-14 51.6 16.0 0.0004 20.4 0.0 11.0 11 1 0 11 11 10 2 HEAT repeat HEAT_EZ PF13513.6 KND99999.1 - 3e-11 43.6 8.2 5.8e-08 33.1 0.0 7.0 7 3 2 9 9 8 1 HEAT-like repeat HEAT_2 PF13646.6 KND99999.1 - 3e-09 37.1 1.2 0.099 13.0 0.0 7.4 3 2 3 7 7 7 2 HEAT repeats IBN_N PF03810.19 KND99999.1 - 6.4e-09 35.6 0.7 1.1e-06 28.4 0.1 3.7 2 1 1 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.23 KND99999.1 - 1.4e-06 28.2 4.3 0.017 15.2 0.0 5.8 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KND99999.1 - 2.3e-06 27.7 4.1 0.00012 22.2 0.3 4.4 2 2 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KND99999.1 - 2.2e-05 24.2 0.2 0.3 10.6 0.0 4.0 3 1 1 4 4 4 2 CLASP N terminal Tti2 PF10521.9 KND99999.1 - 0.0007 19.2 0.1 2.5 7.5 0.0 4.1 2 1 1 4 4 4 2 Tti2 family TIP120 PF08623.10 KND99999.1 - 0.0051 16.6 0.5 0.79 9.5 0.0 3.8 3 1 1 4 4 4 1 TATA-binding protein interacting (TIP20) Telomere_reg-2 PF10193.9 KND99999.1 - 0.038 14.4 0.4 0.31 11.5 0.1 2.7 2 0 0 2 2 2 0 Telomere length regulation protein ZIP4_domain PF18292.1 KND99999.1 - 0.15 12.0 0.7 0.69 9.8 0.7 2.2 1 1 0 1 1 1 0 Zinc transporter ZIP4 domain PAP2 PF01569.21 KNE00002.1 - 1e-16 60.9 1.6 1.5e-16 60.4 1.6 1.3 1 0 0 1 1 1 1 PAP2 superfamily DUF4203 PF13886.6 KNE00002.1 - 0.095 12.3 8.4 0.14 11.8 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) DUF212 PF02681.14 KNE00002.1 - 0.62 10.2 3.2 18 5.5 0.5 2.3 1 1 1 2 2 2 0 Divergent PAP2 family ArfGap PF01412.18 KNE00003.1 - 1.6e-32 112.0 0.8 3.9e-32 110.8 0.0 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf adh_short_C2 PF13561.6 KNE00004.1 - 5.1e-44 150.6 1.0 6.5e-44 150.2 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNE00004.1 - 2.5e-34 118.5 0.8 3e-34 118.2 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KNE00004.1 - 1.7e-09 37.9 0.9 2.5e-09 37.3 0.9 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KNE00004.1 - 0.016 14.7 0.8 0.022 14.2 0.2 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family SMK-1 PF04802.15 KNE00005.1 - 3.8e-48 163.9 5.9 8.1e-46 156.3 2.0 2.4 2 0 0 2 2 2 2 Component of IIS longevity pathway SMK-1 WH1 PF00568.23 KNE00005.1 - 0.033 14.1 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 WH1 domain ATP12 PF07542.11 KNE00007.1 - 5.9e-33 113.7 0.1 9e-33 113.1 0.1 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Prefoldin_2 PF01920.20 KNE00008.1 - 5.6e-11 42.3 3.0 6.6e-11 42.1 3.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit PP-binding_2 PF14573.6 KNE00008.1 - 0.00062 20.0 0.5 0.00073 19.7 0.5 1.3 1 0 0 1 1 1 1 Acyl-carrier DivIVA PF05103.13 KNE00008.1 - 0.0082 16.2 2.7 0.0094 16.0 0.5 1.9 2 0 0 2 2 2 1 DivIVA protein RasGAP_C PF03836.15 KNE00008.1 - 0.014 15.6 3.1 0.22 11.7 0.3 2.1 2 0 0 2 2 2 0 RasGAP C-terminus NPV_P10 PF05531.12 KNE00008.1 - 0.023 15.1 5.0 1.4 9.4 0.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Peptidase_M32 PF02074.15 KNE00008.1 - 0.024 13.4 0.3 0.028 13.2 0.3 1.0 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase Laminin_II PF06009.12 KNE00008.1 - 0.059 13.4 4.3 0.2 11.7 0.7 2.0 2 0 0 2 2 2 0 Laminin Domain II Tropomyosin_1 PF12718.7 KNE00008.1 - 0.076 13.2 4.0 1.7 8.8 0.5 2.1 2 0 0 2 2 2 0 Tropomyosin like DUF2508 PF10704.9 KNE00008.1 - 0.087 13.0 1.9 2 8.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Herpes_heli_pri PF05774.11 KNE00008.1 - 0.096 12.9 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus helicase-primase complex component Prefoldin PF02996.17 KNE00008.1 - 0.1 12.5 5.5 0.6 10.0 0.4 2.4 2 1 1 3 3 3 0 Prefoldin subunit KxDL PF10241.9 KNE00008.1 - 0.11 12.7 4.2 0.5 10.7 1.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein DHR10 PF18595.1 KNE00008.1 - 0.12 12.5 3.7 2.6 8.1 0.6 2.3 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain Baculo_PEP_C PF04513.12 KNE00008.1 - 0.16 12.0 9.2 0.34 10.9 3.7 2.0 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3552 PF12072.8 KNE00008.1 - 0.31 10.4 3.9 0.92 8.9 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF948 PF06103.11 KNE00008.1 - 0.95 9.8 7.1 0.48 10.7 1.6 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) UPF0449 PF15136.6 KNE00008.1 - 2 8.9 5.8 12 6.4 0.5 2.3 1 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Gon7 PF08738.10 KNE00009.1 - 3.4e-25 88.2 0.0 4e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 Gon7 family 6PF2K PF01591.18 KNE00010.1 - 7e-55 185.8 0.0 1e-54 185.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KNE00010.1 - 4.7e-13 49.3 0.0 6.8e-11 42.2 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) VP4_haemagglut PF00426.18 KNE00010.1 - 0.0086 16.3 0.8 0.015 15.5 0.8 1.4 1 0 0 1 1 1 1 Outer Capsid protein VP4 (Hemagglutinin) Concanavalin-like domain AAA_33 PF13671.6 KNE00010.1 - 0.044 13.9 0.0 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KNE00010.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Ribosomal_L26 PF16906.5 KNE00011.1 - 3e-23 82.1 0.8 3.5e-23 81.8 0.8 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KNE00011.1 - 0.0039 17.1 0.7 0.0056 16.6 0.1 1.5 2 0 0 2 2 2 1 KOW motif Sensor_TM1 PF13755.6 KNE00011.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain TIM21 PF08294.11 KNE00012.1 - 2.2e-38 131.4 0.0 2.5e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 TIM21 Glyco_hydro_72 PF03198.14 KNE00014.1 - 5.1e-104 347.9 0.0 6.5e-104 347.6 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KNE00014.1 - 2.5e-07 31.3 0.0 5.4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 X8 domain Arf PF00025.21 KNE00017.1 - 6.7e-45 152.7 0.1 7.7e-45 152.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KNE00017.1 - 6.4e-11 42.0 0.0 7.4e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KNE00017.1 - 1.1e-09 38.6 0.1 2.2e-09 37.6 0.1 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KNE00017.1 - 2.1e-08 33.8 0.9 0.00059 19.1 0.2 2.5 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KNE00017.1 - 4e-08 33.3 0.0 8.3e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KNE00017.1 - 3.1e-07 30.1 0.0 1.3e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.22 KNE00017.1 - 1e-06 28.4 0.0 1.2e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Ras family cobW PF02492.19 KNE00017.1 - 0.0075 15.9 0.0 0.029 14.0 0.0 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KNE00017.1 - 0.012 15.6 0.1 2 8.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 KNE00017.1 - 0.032 13.7 3.0 2.7 7.5 3.0 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 KNE00017.1 - 0.044 13.2 0.0 0.073 12.5 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 KNE00017.1 - 0.056 13.5 0.4 0.72 9.9 0.0 2.3 2 1 1 3 3 3 0 Dynamin family Septin PF00735.18 KNE00017.1 - 0.074 12.3 0.1 4.4 6.5 0.1 2.1 2 0 0 2 2 2 0 Septin AAA_29 PF13555.6 KNE00017.1 - 0.18 11.5 0.3 0.96 9.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain DRMBL PF07522.14 KNE00018.1 - 8.5e-20 71.0 0.1 1.6e-19 70.1 0.1 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 KNE00018.1 - 0.19 11.7 0.8 0.43 10.6 0.8 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF1751 PF08551.10 KNE00019.1 - 4.1e-24 85.0 2.4 4.1e-24 85.0 2.4 2.0 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Phageshock_PspG PF09583.10 KNE00019.1 - 0.0084 16.4 0.9 0.0084 16.4 0.9 4.0 4 0 0 4 4 4 2 Phage shock protein G (Phageshock_PspG) Rhomboid PF01694.22 KNE00019.1 - 0.87 9.6 9.2 1.7 8.7 9.2 1.4 1 0 0 1 1 1 0 Rhomboid family COPI_C PF06957.11 KNE00020.1 - 0.057 12.2 0.1 0.062 12.0 0.1 1.0 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Glyco_transf_34 PF05637.12 KNE00021.1 - 2.7e-48 164.8 0.2 3.6e-48 164.4 0.2 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF3605 PF12239.8 KNE00021.1 - 0.0017 18.7 0.9 0.02 15.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3605) Glucan_synthase PF02364.15 KNE00023.1 - 0 1326.4 0.0 0 1326.4 0.0 2.5 3 0 0 3 3 3 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KNE00023.1 - 2.1e-41 141.2 0.2 5.7e-41 139.9 0.2 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 eIF2A PF08662.11 KNE00024.1 - 2.8e-76 255.7 0.0 4.3e-76 255.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Sel1 PF08238.12 KNE00025.1 - 1.3e-13 51.1 2.8 2.4e-05 24.9 0.0 5.3 5 0 0 5 5 5 3 Sel1 repeat TPR_17 PF13431.6 KNE00025.1 - 0.0093 16.3 0.2 0.11 12.9 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat HCNGP PF07818.13 KNE00025.1 - 0.087 13.5 1.3 21 5.8 0.0 2.9 2 0 0 2 2 2 0 HCNGP-like protein TPR_2 PF07719.17 KNE00025.1 - 0.089 13.0 6.5 0.75 10.1 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KNE00025.1 - 0.098 12.5 4.8 1.6 8.7 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat SHR3_chaperone PF08229.11 KNE00025.1 - 0.13 11.2 0.1 0.3 10.0 0.1 1.5 1 0 0 1 1 1 0 ER membrane protein SH3 TPR_8 PF13181.6 KNE00025.1 - 0.46 10.8 0.0 0.46 10.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat CCDC-167 PF15188.6 KNE00025.1 - 0.76 10.2 2.7 1.6 9.1 0.0 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Lzipper-MIP1 PF14389.6 KNE00025.1 - 4.6 7.6 7.2 0.88 9.9 2.9 2.1 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 GATA PF00320.27 KNE00029.1 - 2e-14 52.9 3.9 3.6e-14 52.1 3.9 1.4 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 KNE00029.1 - 0.0002 21.1 0.1 0.00046 20.0 0.1 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.12 KNE00029.1 - 0.005 16.3 0.3 0.0096 15.4 0.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding ArfGap PF01412.18 KNE00029.1 - 0.075 13.1 0.3 0.25 11.4 0.3 1.8 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Elf1 PF05129.13 KNE00029.1 - 0.12 12.5 0.1 0.27 11.3 0.1 1.7 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like SF3b10 PF07189.11 KNE00031.1 - 1.1e-29 102.4 0.2 1.2e-29 102.2 0.2 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) E1-E2_ATPase PF00122.20 KNE00032.1 - 4.4e-31 107.8 17.3 1e-29 103.4 1.9 3.8 5 0 0 5 5 5 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KNE00032.1 - 8.5e-26 90.8 3.1 8.5e-26 90.8 3.1 2.9 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KNE00032.1 - 2.9e-17 63.7 0.0 2.4e-16 60.6 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KNE00032.1 - 1.1e-13 51.1 0.0 2.3e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KNE00032.1 - 3.7e-05 23.6 1.0 0.00035 20.4 0.4 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase CAP_GLY PF01302.25 KNE00033.1 - 3e-13 49.6 0.4 5.5e-13 48.7 0.4 1.5 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 KNE00033.1 - 0.0057 16.5 0.7 0.011 15.7 0.7 1.4 1 0 0 1 1 1 1 CLIP1 zinc knuckle FAM76 PF16046.5 KNE00033.1 - 0.0073 15.7 11.7 0.0073 15.7 11.7 4.0 1 1 3 4 4 4 2 FAM76 protein SHE3 PF17078.5 KNE00033.1 - 0.43 10.3 67.5 0.015 15.0 15.5 3.8 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 Cast PF10174.9 KNE00033.1 - 1.5 7.0 74.1 5 5.2 74.1 1.6 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone ATG16 PF08614.11 KNE00033.1 - 1.8 8.7 85.6 0.029 14.6 19.8 5.1 1 1 2 4 4 4 0 Autophagy protein 16 (ATG16) NUP214 PF16755.5 KNE00034.1 - 9e-25 87.7 0.1 1.4e-19 70.6 0.0 2.6 2 0 0 2 2 2 2 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 NYD-SP28 PF14772.6 KNE00034.1 - 8.6 6.5 11.4 2.6 8.1 7.5 2.2 2 0 0 2 2 2 0 Sperm tail XhlA PF10779.9 KNE00034.1 - 9.5 6.5 11.0 1 9.6 0.8 3.4 3 0 0 3 3 3 0 Haemolysin XhlA STD1 PF17235.2 KNE00035.1 - 1.8e-56 191.0 7.7 3.1e-56 190.3 7.7 1.3 1 0 0 1 1 1 1 STD1/MTH1 Fcf2 PF08698.11 KNE00036.1 - 7.7e-35 119.2 2.7 7.7e-35 119.2 2.7 2.5 3 0 0 3 3 3 1 Fcf2 pre-rRNA processing Integrin_alpha PF00357.20 KNE00036.1 - 2.5 8.3 6.5 2.3 8.4 0.2 3.2 2 0 0 2 2 2 0 Integrin alpha cytoplasmic region AAA_lid_9 PF17871.1 KNE00036.1 - 5 7.1 10.5 2.9 7.8 2.7 2.7 1 1 1 2 2 2 0 AAA lid domain zf-H2C2_2 PF13465.6 KNE00037.1 - 1.1e-06 28.7 3.3 1.1e-06 28.7 3.3 2.1 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 KNE00037.1 - 0.00024 21.4 11.4 0.00074 19.8 0.3 3.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 KNE00037.1 - 0.0003 21.4 16.4 0.015 15.9 0.2 4.2 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KNE00037.1 - 0.0033 18.1 7.9 0.033 15.0 0.4 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger FlaF PF07309.11 KNE00037.1 - 0.054 13.5 0.9 0.13 12.2 0.7 1.7 2 0 0 2 2 2 0 Flagellar protein FlaF zf-C2H2_jaz PF12171.8 KNE00037.1 - 0.065 13.5 1.3 0.16 12.3 0.8 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 KNE00037.1 - 0.36 11.5 4.0 1.1 9.9 0.2 2.7 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats Zap1_zf2 PF18217.1 KNE00037.1 - 1.5 8.9 6.1 1.9 8.5 0.8 3.1 3 1 0 3 3 3 0 Zap1 zinc finger 2 tRNA-synt_2d PF01409.20 KNE00038.1 - 3.1e-88 295.4 0.0 4.7e-88 294.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KNE00038.1 - 1.2e-14 54.3 1.3 2.5e-14 53.3 0.2 2.3 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KNE00038.1 - 2.5e-08 33.6 0.0 2.8e-06 26.9 0.0 2.1 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 KNE00038.1 - 0.00014 21.1 0.2 0.0028 16.8 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 KNE00038.1 - 0.00019 21.5 0.0 0.00036 20.5 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) PheRS_DBD2 PF18554.1 KNE00038.1 - 0.0022 17.9 2.5 0.0053 16.7 2.5 1.7 1 0 0 1 1 1 1 PheRS DNA binding domain 2 DUF4019 PF13211.6 KNE00039.1 - 0.14 12.5 0.0 0.15 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4019) Pyr_redox_2 PF07992.14 KNE00042.1 - 2e-66 224.2 4.3 2e-66 224.2 4.3 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KNE00042.1 - 1.2e-41 141.4 0.8 2e-41 140.7 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KNE00042.1 - 8.2e-20 71.2 7.6 5.6e-18 65.3 1.5 3.6 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KNE00042.1 - 7.4e-09 35.7 3.0 0.0012 19.0 0.2 2.8 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KNE00042.1 - 3.7e-08 33.0 4.9 7.6e-06 25.4 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KNE00042.1 - 4.2e-08 32.7 1.9 5.7e-06 25.7 0.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 KNE00042.1 - 3.6e-06 26.6 4.3 3.6e-05 23.3 0.0 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KNE00042.1 - 7.3e-06 25.4 3.3 0.0039 16.5 0.0 2.4 2 1 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 KNE00042.1 - 8.1e-05 21.5 7.4 0.027 13.2 0.0 3.4 2 1 1 3 3 3 2 HI0933-like protein 3HCDH_N PF02737.18 KNE00042.1 - 0.0011 18.9 0.9 0.0022 17.9 0.9 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.6 KNE00042.1 - 0.0014 17.9 0.2 1.5 7.9 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KNE00042.1 - 0.0015 17.8 8.3 0.3 10.3 3.3 3.1 2 1 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 KNE00042.1 - 0.0017 17.5 0.6 0.0017 17.5 0.6 2.3 2 1 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KNE00042.1 - 0.0019 17.6 2.1 0.0035 16.7 0.2 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KNE00042.1 - 0.0059 15.7 1.2 2.5 7.1 0.0 2.9 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.24 KNE00042.1 - 0.027 14.0 14.7 1 8.8 2.6 3.5 2 2 1 3 3 3 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KNE00042.1 - 0.24 11.9 0.9 3.7 8.0 0.4 3.0 2 1 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KNE00042.1 - 0.33 10.5 4.1 0.069 12.7 0.5 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Mannosyl_trans3 PF11051.8 KNE00043.1 - 2.5e-66 223.9 0.0 5e-66 222.9 0.0 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative GerPC PF10737.9 KNE00043.1 - 0.0075 16.4 0.4 0.018 15.1 0.4 1.6 1 0 0 1 1 1 1 Spore germination protein GerPC Ribosomal_S16 PF00886.19 KNE00043.1 - 0.15 12.1 0.3 1.1 9.3 0.0 2.5 3 0 0 3 3 3 0 Ribosomal protein S16 Glycos_transf_2 PF00535.26 KNE00045.1 - 1.6e-25 89.9 0.0 2e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KNE00045.1 - 5.1e-12 46.2 0.0 7.3e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KNE00045.1 - 8.3e-06 25.5 0.0 1.1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KNE00045.1 - 0.00022 21.7 0.0 0.00044 20.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 mRNA_triPase PF02940.15 KNE00046.1 - 7.5e-55 186.0 0.3 1.2e-54 185.4 0.3 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Iso_dh PF00180.20 KNE00047.1 - 3.5e-72 243.5 0.0 4e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MT-A70 PF05063.14 KNE00048.1 - 7.3e-09 35.8 0.0 2.5e-07 30.8 0.0 2.2 1 1 0 1 1 1 1 MT-A70 Voltage_CLC PF00654.20 KNE00050.1 - 1.9e-83 280.7 17.9 1.9e-83 280.7 17.9 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel PqiA PF04403.13 KNE00050.1 - 0.017 14.9 2.3 0.022 14.6 0.1 2.3 2 0 0 2 2 2 0 Paraquat-inducible protein A CBS PF00571.28 KNE00050.1 - 0.039 14.4 0.0 0.092 13.2 0.0 1.6 1 0 0 1 1 1 0 CBS domain UL45 PF05473.12 KNE00050.1 - 0.05 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like DUF543 PF04418.12 KNE00052.1 - 5.9e-17 61.4 6.3 6.6e-17 61.3 6.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Pkinase PF00069.25 KNE00053.1 - 4.5e-72 242.6 0.0 6.6e-72 242.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE00053.1 - 2.4e-48 164.7 0.3 4.4e-48 163.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 KNE00053.1 - 7.9e-12 45.4 0.0 5e-11 42.8 0.0 2.5 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 KNE00053.1 - 9.2e-06 25.2 0.2 1.9e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KNE00053.1 - 3.8e-05 22.7 0.5 0.00012 21.0 0.5 1.9 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KNE00053.1 - 0.066 13.1 0.8 0.51 10.2 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family DSHCT PF08148.12 KNE00053.1 - 0.097 12.3 0.1 0.22 11.2 0.1 1.6 1 1 0 1 1 1 0 DSHCT (NUC185) domain DUF3292 PF11696.8 KNE00053.1 - 7.6 4.8 7.9 14 3.9 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Haspin_kinase PF12330.8 KNE00053.1 - 7.6 5.4 6.5 4.9 6.0 3.6 2.3 2 1 0 2 2 2 0 Haspin like kinase domain Glu-tRNAGln PF02686.15 KNE00055.1 - 0.0092 16.3 0.1 0.045 14.1 0.0 2.1 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit DUF2040 PF09745.9 KNE00056.1 - 0.0083 16.2 11.5 0.018 15.1 7.4 2.2 1 1 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) CdiI_4 PF18624.1 KNE00056.1 - 0.026 15.0 0.1 0.038 14.5 0.1 1.4 1 0 0 1 1 1 0 CDI immunity protein DUF2408 PF10303.9 KNE00056.1 - 0.033 14.8 3.6 0.042 14.4 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) SUIM_assoc PF16619.5 KNE00056.1 - 9.6 6.4 8.6 0.54 10.4 0.4 2.6 2 1 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Band_7 PF01145.25 KNE00058.1 - 1.8e-29 103.0 1.3 2.6e-29 102.5 1.3 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KNE00058.1 - 0.00041 20.1 0.1 0.00062 19.5 0.1 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family Fungal_trans_2 PF11951.8 KNE00059.1 - 7.6e-59 199.4 0.2 9.1e-59 199.2 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNE00059.1 - 0.0011 19.0 6.4 0.0011 19.0 6.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ApbA PF02558.16 KNE00060.1 - 3.1e-27 95.1 0.1 4.4e-27 94.6 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KNE00060.1 - 6.8e-25 87.7 0.1 1.7e-24 86.4 0.1 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal Ldh_1_N PF00056.23 KNE00060.1 - 0.029 14.5 0.2 0.072 13.2 0.0 1.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain DAO PF01266.24 KNE00060.1 - 0.04 13.5 0.2 0.063 12.8 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KNE00060.1 - 0.061 12.6 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KNE00060.1 - 0.085 13.4 0.2 0.19 12.3 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KNE00060.1 - 0.089 11.9 0.3 0.16 11.0 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.21 KNE00060.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 ThiF family Aminotran_3 PF00202.21 KNE00061.1 - 2.7e-62 210.7 0.0 3.3e-62 210.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DUF3456 PF11938.8 KNE00061.1 - 0.097 13.2 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP DcrB PF08786.11 KNE00061.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 DcrB tRNA_int_endo PF01974.17 KNE00062.1 - 4.9e-24 84.2 0.7 8.9e-24 83.4 0.1 1.7 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KNE00062.1 - 0.014 15.0 0.4 1.4 8.6 0.4 2.5 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain CBFD_NFYB_HMF PF00808.23 KNE00064.1 - 4.8e-14 52.4 2.5 7.3e-14 51.8 2.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KNE00064.1 - 0.00017 22.0 0.2 0.00022 21.6 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 KNE00064.1 - 0.1 12.7 1.6 0.18 11.9 1.6 1.4 1 0 0 1 1 1 0 hTAFII28-like protein conserved region FGGY_C PF02782.16 KNE00066.1 - 2.7e-54 183.9 0.3 6e-54 182.8 0.2 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KNE00066.1 - 4.3e-21 75.6 0.0 1.2e-20 74.2 0.0 1.8 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KNE00066.1 - 0.14 11.6 0.1 0.63 9.5 0.1 2.0 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Sulfate_transp PF00916.20 KNE00067.1 - 1.5e-116 389.3 11.1 2.4e-116 388.6 11.1 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KNE00067.1 - 3.5e-07 29.8 0.0 7.4e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KNE00067.1 - 0.011 16.1 0.5 0.011 16.1 0.5 2.3 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily DEAD PF00270.29 KNE00068.1 - 7.3e-46 156.1 1.6 1e-45 155.6 0.8 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNE00068.1 - 8.2e-33 113.1 0.5 4.4e-31 107.5 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNE00068.1 - 4e-07 30.2 0.0 8.2e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KNE00068.1 - 0.00049 19.9 0.1 0.00079 19.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KNE00068.1 - 0.0029 18.0 0.2 0.0064 16.8 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KNE00068.1 - 0.01 16.1 0.2 0.041 14.2 0.2 2.0 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 KNE00068.1 - 0.014 14.7 0.0 0.052 12.9 0.0 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit TniB PF05621.11 KNE00068.1 - 0.016 14.6 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Flavi_DEAD PF07652.14 KNE00068.1 - 0.026 14.5 0.1 0.19 11.7 0.1 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain Glyco_transf_8 PF01501.20 KNE00069.1 - 7.2e-17 61.8 0.0 3.2e-16 59.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 DNA_pol_phi PF04931.13 KNE00069.1 - 0.59 8.2 11.4 0.91 7.6 11.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi tRNA_U5-meth_tr PF05958.11 KNE00071.1 - 1.6e-19 70.1 0.8 2.2e-18 66.4 0.3 2.3 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.20 KNE00071.1 - 1.3e-10 41.1 0.0 2.5e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 TRAM domain Methyltransf_31 PF13847.6 KNE00071.1 - 4.6e-07 29.7 0.0 9.1e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNE00071.1 - 6.1e-06 26.9 0.0 1.3e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 KNE00071.1 - 4.2e-05 23.2 0.1 8.7e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 KNE00071.1 - 8e-05 22.2 0.1 0.00014 21.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 KNE00071.1 - 0.00011 22.0 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 KNE00071.1 - 0.00024 20.9 0.0 0.00049 19.9 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 KNE00071.1 - 0.0018 18.9 0.0 0.0041 17.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KNE00071.1 - 0.0024 17.4 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KNE00071.1 - 0.03 13.6 0.0 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family ATP-grasp_4 PF13535.6 KNE00071.1 - 0.058 13.0 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 ATP-grasp domain PAP2 PF01569.21 KNE00073.1 - 4.7e-15 55.5 5.6 4.7e-15 55.5 5.6 2.0 2 0 0 2 2 2 1 PAP2 superfamily Ras PF00071.22 KNE00074.1 - 4.6e-47 159.6 0.0 5.8e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNE00074.1 - 6e-23 81.3 0.0 9.6e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNE00074.1 - 4.6e-08 32.7 0.0 7.3e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family NB-ARC PF00931.22 KNE00074.1 - 0.076 12.2 0.0 0.21 10.7 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 KNE00074.1 - 0.13 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 KNE00074.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KNE00074.1 - 0.19 12.0 0.1 1.5 9.1 0.1 2.4 1 1 1 2 2 2 0 AAA domain DUF2401 PF10287.9 KNE00076.1 - 7.8e-92 307.0 0.1 7.8e-92 307.0 0.1 2.0 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 KNE00076.1 - 2.9e-29 101.3 0.1 6.3e-29 100.2 0.1 1.6 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Macoilin PF09726.9 KNE00076.1 - 4.1 5.8 7.6 5 5.5 7.6 1.1 1 0 0 1 1 1 0 Macoilin family Gryzun-like PF12742.7 KNE00077.1 - 0.13 12.2 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking FGGY_C PF02782.16 KNE00078.1 - 2.3e-06 27.5 0.0 4.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KNE00078.1 - 0.004 16.8 0.0 0.009 15.6 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DUF1027 PF06265.11 KNE00078.1 - 0.14 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) Zn_clus PF00172.18 KNE00079.1 - 3.4e-09 36.7 11.3 5.4e-09 36.0 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain vATP-synt_E PF01991.18 KNE00080.1 - 6.3e-62 208.5 22.4 7e-62 208.4 22.4 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit VTC PF09359.10 KNE00080.1 - 0.017 14.5 4.2 0.02 14.3 4.2 1.2 1 0 0 1 1 1 0 VTC domain DUF4162 PF13732.6 KNE00080.1 - 5 7.9 9.9 0.62 10.8 3.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4162) Asp-B-Hydro_N PF05279.11 KNE00080.1 - 8.6 6.3 18.1 0.28 11.2 9.9 2.0 1 1 1 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region CorA PF01544.18 KNE00082.1 - 1.1e-05 24.9 5.9 4.3e-05 23.0 5.9 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein RPA43_OB PF17875.1 KNE00083.1 - 2.7e-26 92.6 0.3 2.7e-26 92.6 0.3 2.2 2 1 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 KNE00083.1 - 1.8e-13 50.6 0.0 3.1e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 MetOD2 PF18548.1 KNE00084.1 - 0.11 12.6 2.0 1.6 8.9 0.0 2.8 2 0 0 2 2 2 0 Metanogen output domain 2 DUF4160 PF13711.6 KNE00084.1 - 0.12 12.7 0.7 21 5.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) Mis12 PF05859.12 KNE00086.1 - 1.7e-40 138.2 0.9 1.7e-40 138.2 0.9 2.0 1 1 1 2 2 2 2 Mis12 protein GlnD_UR_UTase PF08335.11 KNE00086.1 - 0.1 12.7 1.0 0.21 11.7 1.0 1.5 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase SWIRM PF04433.17 KNE00090.1 - 4.3e-10 39.8 0.0 1.1e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain Flavi_NS4B PF01349.17 KNE00090.1 - 0.064 12.6 0.0 0.091 12.1 0.0 1.2 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4B Dus PF01207.17 KNE00093.1 - 1.9e-48 165.2 0.0 3.4e-48 164.3 0.0 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) NCD1 PF04904.13 KNE00093.1 - 0.079 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) COX5A PF02284.16 KNE00093.1 - 0.08 13.0 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va DNA_pol_P_Exo PF18049.1 KNE00093.1 - 0.15 11.4 0.0 0.32 10.4 0.0 1.5 2 0 0 2 2 2 0 DNA polymerase nu pseudo-exo Tim17 PF02466.19 KNE00094.1 - 2.4e-24 85.8 0.4 3.5e-24 85.3 0.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Sugar_tr PF00083.24 KNE00095.1 - 1.8e-101 340.3 15.9 2.3e-101 339.9 15.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNE00095.1 - 1e-20 74.0 23.3 3e-15 56.0 8.0 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KNE00095.1 - 0.0029 16.1 1.2 0.0029 16.1 1.2 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF697 PF05128.12 KNE00095.1 - 0.026 14.3 2.0 0.058 13.1 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF697) Sugar_tr PF00083.24 KNE00098.1 - 4.6e-99 332.3 21.8 5.9e-99 331.9 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNE00098.1 - 1.9e-17 63.2 30.9 6.6e-13 48.3 13.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1899 PF08953.11 KNE00099.1 - 0.094 12.6 0.0 0.4 10.6 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1899) Sugar_tr PF00083.24 KNE00100.1 - 1e-100 337.7 21.1 1.2e-100 337.5 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNE00100.1 - 1.8e-22 79.8 29.0 3.3e-17 62.5 11.9 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KNE00100.1 - 1.5e-05 23.8 16.0 0.0013 17.4 1.9 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein DUF697 PF05128.12 KNE00100.1 - 0.19 11.5 0.7 0.46 10.2 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF697) DUF3281 PF11685.8 KNE00102.1 - 0.0015 17.9 0.1 0.0018 17.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3281) ACC_central PF08326.12 KNE00103.1 - 6.9e-264 877.5 0.1 9e-264 877.2 0.1 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KNE00103.1 - 1.5e-181 604.4 0.0 2.1e-181 603.9 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KNE00103.1 - 2e-52 177.8 0.0 4.3e-52 176.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KNE00103.1 - 7.4e-30 103.7 0.1 1.5e-29 102.7 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KNE00103.1 - 5.2e-23 81.2 0.0 5.3e-21 74.7 0.0 3.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KNE00103.1 - 2.8e-18 65.5 0.4 8e-18 64.1 0.4 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 KNE00103.1 - 0.00013 22.0 0.1 0.00096 19.2 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KNE00103.1 - 0.0021 17.6 0.0 0.0067 16.0 0.0 1.8 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KNE00103.1 - 0.0066 16.2 0.1 4.7 7.1 0.0 2.6 2 0 0 2 2 2 2 Biotin-lipoyl like ATPgrasp_Ter PF15632.6 KNE00103.1 - 0.058 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon GxGYxYP_N PF16216.5 KNE00103.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal Peptidase_S8 PF00082.22 KNE00104.1 - 2.2e-29 102.6 1.3 3.3e-29 102.1 1.3 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KNE00104.1 - 1.2e-05 25.8 0.0 2.8e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Glucan_synthase PF02364.15 KNE00105.1 - 0 1212.2 0.2 0 1211.9 0.2 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KNE00105.1 - 4e-36 124.2 4.3 5.3e-35 120.6 4.3 2.6 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 TPR_2 PF07719.17 KNE00106.1 - 1.4e-13 49.9 0.8 4.4e-05 23.3 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KNE00106.1 - 8.7e-12 44.3 0.9 4.8e-05 23.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KNE00106.1 - 7.2e-07 28.8 2.5 0.00011 21.8 0.3 2.5 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 KNE00106.1 - 1.2e-06 28.2 0.6 4.1e-05 23.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat RPAP3_C PF13877.6 KNE00106.1 - 1.4e-06 28.7 0.5 7.5e-06 26.4 0.1 2.1 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 TPR_19 PF14559.6 KNE00106.1 - 2.5e-05 24.7 1.7 0.026 15.0 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KNE00106.1 - 3e-05 24.6 1.8 0.0064 17.1 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KNE00106.1 - 0.00041 20.9 1.1 0.15 12.9 0.1 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KNE00106.1 - 0.0048 17.0 0.7 0.055 13.6 0.2 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KNE00106.1 - 0.0052 16.8 0.4 0.019 15.0 0.1 2.1 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 KNE00106.1 - 0.019 15.3 0.6 2.3 8.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KNE00106.1 - 0.08 13.2 1.5 21 5.5 0.1 2.9 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 KNE00106.1 - 0.097 12.7 0.9 0.26 11.3 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat UPF0029 PF01205.19 KNE00107.1 - 2.6e-14 53.4 0.5 5.6e-14 52.4 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KNE00107.1 - 1.2e-09 38.5 1.0 1.2e-09 38.5 1.0 2.0 2 1 0 2 2 2 1 RWD domain Ofd1_CTDD PF10637.9 KNE00107.1 - 0.047 13.0 0.3 0.059 12.7 0.3 1.2 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Glyco_trans_1_2 PF13524.6 KNE00107.1 - 0.1 13.0 0.2 1.5 9.3 0.1 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 UPF0029 PF01205.19 KNE00108.1 - 2.5e-13 50.2 0.0 2.8e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 MPP6 PF10175.9 KNE00109.1 - 1.2e-11 45.2 17.4 2e-11 44.5 17.4 1.3 1 0 0 1 1 1 1 M-phase phosphoprotein 6 WD40 PF00400.32 KNE00110.1 - 2.1e-40 136.0 11.0 1.7e-07 31.8 0.1 10.3 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNE00110.1 - 1.3e-21 76.7 0.1 0.0069 16.7 0.0 9.3 4 2 6 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KNE00110.1 - 4.8e-21 75.1 0.0 7.5e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 KNE00110.1 - 2.7e-07 29.9 1.5 0.07 12.1 0.0 5.7 3 3 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KNE00110.1 - 0.00033 19.5 0.7 1.4 7.4 0.0 3.6 3 1 1 4 4 4 2 Nucleoporin Nup120/160 WD40_3 PF15911.5 KNE00110.1 - 0.00076 19.4 0.0 0.0032 17.4 0.0 2.1 1 0 0 1 1 1 1 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 KNE00110.1 - 0.024 13.2 0.5 8.4 4.8 0.0 3.3 3 1 1 4 4 4 0 Cytochrome D1 heme domain NOA36 PF06524.12 KNE00110.1 - 0.53 9.5 6.2 6.3 6.0 1.5 2.2 2 0 0 2 2 2 0 NOA36 protein S-antigen PF05756.11 KNE00110.1 - 9.7 6.6 12.0 0.54 10.7 1.6 2.6 2 0 0 2 2 2 0 S-antigen protein Glycogen_syn PF05693.13 KNE00113.1 - 0 1130.3 0.0 0 1130.0 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_trans_1_4 PF13692.6 KNE00113.1 - 6.2e-07 29.9 0.0 0.0028 18.1 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KNE00113.1 - 7.9e-07 28.8 0.0 6.6e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KNE00113.1 - 5e-06 27.0 0.3 1.5e-05 25.5 0.0 2.0 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KNE00113.1 - 3.1e-05 24.0 1.9 3.5e-05 23.9 0.7 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 KNE00113.1 - 3.7e-05 23.5 0.1 7.6e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain LSM PF01423.22 KNE00115.1 - 1.2e-16 60.1 0.2 2.2e-16 59.3 0.2 1.5 1 0 0 1 1 1 1 LSM domain NT-C2 PF10358.9 KNE00117.1 - 6.5e-36 123.2 0.3 9.7e-36 122.7 0.3 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins SR-25 PF10500.9 KNE00118.1 - 0.017 14.7 6.1 0.029 14.0 6.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FeS_assembly_P PF01883.19 KNE00119.1 - 1.8e-08 34.5 0.0 3.2e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein Foie-gras_1 PF11817.8 KNE00120.1 - 2.3e-15 56.9 3.2 2.5e-13 50.2 3.2 2.3 1 1 0 1 1 1 1 Foie gras liver health family 1 TPR_1 PF00515.28 KNE00120.1 - 0.02 14.7 0.1 0.064 13.1 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 KNE00120.1 - 0.048 13.9 1.2 3.6 8.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KNE00120.1 - 0.063 13.4 0.2 0.48 10.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KNE00120.1 - 0.14 11.9 0.1 5.4 6.8 0.0 2.5 2 0 0 2 2 2 0 TPR repeat FKBP_C PF00254.28 KNE00122.1 - 1e-33 115.5 0.0 1.2e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Arrestin_N PF00339.29 KNE00123.1 - 1.8e-13 50.8 0.3 1.7e-08 34.6 0.1 2.7 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain TPR_2 PF07719.17 KNE00125.1 - 1.1e-28 97.0 27.9 6.7e-06 25.8 0.0 10.5 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_17 PF13431.6 KNE00125.1 - 3.3e-22 77.2 1.0 0.0035 17.6 0.0 7.4 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 KNE00125.1 - 1.4e-21 75.3 30.2 9.4e-06 25.2 0.1 10.4 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 KNE00125.1 - 9.5e-21 74.2 6.7 5.4e-06 26.9 0.0 6.4 5 1 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 KNE00125.1 - 2.6e-17 62.9 11.3 0.00044 20.5 0.1 7.6 5 2 3 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 KNE00125.1 - 3.1e-16 58.2 23.6 0.00031 20.7 0.0 10.3 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 KNE00125.1 - 7.9e-16 58.3 15.6 0.001 19.5 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KNE00125.1 - 3.8e-15 55.3 21.9 5.6e-05 22.7 0.2 8.8 7 1 2 9 9 8 5 TPR repeat TPR_14 PF13428.6 KNE00125.1 - 6.9e-11 42.0 13.4 0.35 11.8 0.0 9.0 6 4 4 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 KNE00125.1 - 1e-07 31.4 5.8 0.39 10.8 0.0 7.7 9 0 0 9 9 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KNE00125.1 - 1.9e-07 31.2 9.0 1.4e-05 25.2 0.1 4.6 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 KNE00125.1 - 1.5e-06 28.1 15.4 0.0092 15.7 0.0 5.4 5 1 0 5 5 5 3 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 KNE00125.1 - 1.6e-05 24.5 3.0 0.048 13.0 0.4 3.3 2 1 1 3 3 3 2 MalT-like TPR region TPR_9 PF13371.6 KNE00125.1 - 0.00013 22.1 0.0 10 6.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KNE00125.1 - 0.00049 19.9 15.8 5.4 7.0 0.0 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat AP3D1 PF06375.11 KNE00125.1 - 0.0012 19.1 7.8 0.0012 19.1 4.5 2.4 2 0 0 2 2 2 1 AP-3 complex subunit delta-1 TPR_4 PF07721.14 KNE00125.1 - 0.0026 18.2 0.1 2.6 8.9 0.2 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KNE00125.1 - 0.0037 17.8 22.1 0.19 12.4 0.0 7.8 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_20 PF14561.6 KNE00125.1 - 0.0067 16.7 4.7 16 5.9 0.0 4.8 4 1 1 5 5 4 0 Tetratricopeptide repeat Nefa_Nip30_N PF10187.9 KNE00125.1 - 0.038 14.4 0.9 0.038 14.4 0.9 3.5 3 0 0 3 3 3 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF4810 PF16068.5 KNE00125.1 - 0.053 14.1 0.2 0.47 11.0 0.0 5.5 6 1 1 7 7 6 0 Domain of unknown function (DUF4810) BTAD PF03704.17 KNE00125.1 - 0.12 12.8 5.9 4.1 7.8 0.1 4.9 4 2 2 6 6 6 0 Bacterial transcriptional activator domain PPR_2 PF13041.6 KNE00125.1 - 0.45 10.8 3.1 49 4.2 0.0 4.4 4 0 0 4 4 4 0 PPR repeat family Exonuc_VII_S PF02609.16 KNE00125.1 - 0.47 10.6 7.9 7.5 6.7 0.1 4.3 4 0 0 4 4 4 0 Exonuclease VII small subunit HemY_N PF07219.13 KNE00125.1 - 2.8 8.2 0.0 2.8 8.2 0.0 3.5 4 1 0 4 4 3 0 HemY protein N-terminus DSPc PF00782.20 KNE00126.1 - 5.2e-07 29.5 0.1 8.5e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KNE00126.1 - 1.2e-05 25.0 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KNE00126.1 - 0.0025 17.5 0.1 0.004 16.9 0.1 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Prim-Pol PF09250.11 KNE00126.1 - 0.15 12.4 0.0 0.5 10.7 0.0 1.8 2 0 0 2 2 2 0 Bifunctional DNA primase/polymerase, N-terminal AD PF09793.9 KNE00127.1 - 3.6e-12 46.2 6.2 5.4e-10 39.3 6.2 2.7 1 1 0 1 1 1 1 Anticodon-binding domain PI_PP_I PF18363.1 KNE00127.1 - 0.0049 17.0 4.1 0.0096 16.1 4.1 1.4 1 0 0 1 1 1 1 Phosphoinositide phosphatase insertion domain TFIIA PF03153.13 KNE00127.1 - 0.021 14.9 12.1 0.021 14.8 12.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM222A PF15258.6 KNE00127.1 - 0.024 13.8 10.0 0.026 13.6 10.0 1.2 1 0 0 1 1 1 0 Protein family of FAM222A USP19_linker PF16602.5 KNE00127.1 - 0.051 14.1 0.4 0.096 13.2 0.1 1.5 1 1 0 1 1 1 0 Linker region of USP19 deubiquitinase PRC2_HTH_1 PF18118.1 KNE00127.1 - 0.25 12.2 6.6 0.45 11.3 6.6 1.5 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain FAM70 PF14967.6 KNE00127.1 - 0.31 10.4 1.8 0.41 10.1 1.8 1.1 1 0 0 1 1 1 0 FAM70 protein V_ATPase_I PF01496.19 KNE00127.1 - 0.33 8.8 6.5 0.39 8.6 6.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PAT1 PF09770.9 KNE00127.1 - 0.37 9.0 13.7 0.41 8.9 13.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 REC114-like PF15165.6 KNE00127.1 - 2.7 7.7 10.1 13 5.5 10.1 1.9 1 1 0 1 1 1 0 Meiotic recombination protein REC114-like Presenilin PF01080.17 KNE00127.1 - 3.1 6.5 7.9 3.4 6.3 7.9 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 KNE00127.1 - 4 6.5 6.1 4.3 6.4 6.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 KNE00127.1 - 4.8 7.2 8.0 7.5 6.5 8.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 KNE00127.1 - 7.6 5.2 7.1 8.8 5.0 7.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter YqzE PF14038.6 KNE00129.1 - 0.028 14.4 1.8 0.046 13.7 1.8 1.3 1 0 0 1 1 1 0 YqzE-like protein Cadherin_tail PF15974.5 KNE00129.1 - 2.3 8.5 5.8 2.9 8.2 5.8 1.1 1 0 0 1 1 1 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region CDP-OH_P_transf PF01066.21 KNE00131.1 - 1.2e-06 29.2 0.1 1.2e-06 29.2 0.1 3.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Tom22 PF04281.13 KNE00132.1 - 3.4e-41 140.3 1.4 3.9e-41 140.1 1.4 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Mitoc_L55 PF09776.9 KNE00132.1 - 0.83 9.4 3.8 1.4 8.7 1.6 2.0 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L55 DUF3402 PF11882.8 KNE00133.1 - 1.8e-80 271.4 18.5 6.8e-45 154.0 1.7 2.4 2 1 1 3 3 3 2 Domain of unknown function (DUF3402) N1221 PF07923.13 KNE00133.1 - 1.7e-43 148.9 4.5 5.3e-41 140.7 4.5 2.6 1 1 0 1 1 1 1 N1221-like protein PBP1_TM PF14812.6 KNE00133.1 - 0.85 10.0 5.2 0.32 11.4 1.5 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hydrolase_6 PF13344.6 KNE00134.1 - 3.6e-19 68.8 0.0 8.2e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KNE00134.1 - 1.2e-13 50.9 0.0 1.2e-12 47.7 0.0 2.7 2 1 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KNE00134.1 - 0.036 14.3 0.0 0.33 11.2 0.0 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Kre28 PF17097.5 KNE00135.1 - 3e-06 26.5 24.3 5.2e-06 25.7 24.3 1.4 1 1 0 1 1 1 1 Spindle pole body component GLE1 PF07817.13 KNE00135.1 - 0.00096 18.4 5.4 0.073 12.3 0.8 2.2 2 0 0 2 2 2 2 GLE1-like protein Mod_r PF07200.13 KNE00135.1 - 0.00097 19.3 30.3 0.0078 16.3 11.1 2.7 1 1 2 3 3 3 2 Modifier of rudimentary (Mod(r)) protein ADIP PF11559.8 KNE00135.1 - 0.0024 17.9 24.1 0.0097 16.0 10.2 2.5 2 1 0 2 2 2 2 Afadin- and alpha -actinin-Binding Bacillus_HBL PF05791.11 KNE00135.1 - 0.0098 15.7 12.6 0.37 10.6 4.2 2.8 1 1 1 2 2 2 2 Bacillus haemolytic enterotoxin (HBL) DHR10 PF18595.1 KNE00135.1 - 0.012 15.7 25.8 0.19 11.8 8.5 2.7 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain FUSC PF04632.12 KNE00135.1 - 0.022 13.3 2.4 0.029 12.9 2.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Csm1_N PF18504.1 KNE00135.1 - 0.028 14.8 8.3 0.028 14.8 8.3 4.4 4 1 1 5 5 5 0 Csm1 N-terminal domain ATG16 PF08614.11 KNE00135.1 - 0.034 14.4 25.7 0.078 13.2 9.2 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) UPF0565 PF10561.9 KNE00135.1 - 0.1 11.8 5.9 0.66 9.1 1.6 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0565 GAS PF13851.6 KNE00135.1 - 0.11 11.9 28.9 0.25 10.7 11.6 2.9 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF948 PF06103.11 KNE00135.1 - 0.11 12.8 5.8 0.21 11.9 1.3 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Lectin_N PF03954.14 KNE00135.1 - 0.13 12.0 14.7 1.3 8.7 4.3 3.4 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain MbeD_MobD PF04899.12 KNE00135.1 - 0.33 11.1 7.4 5.2 7.3 0.2 3.0 2 1 1 3 3 2 0 MbeD/MobD like TMF_TATA_bd PF12325.8 KNE00135.1 - 0.37 11.0 29.1 0.15 12.3 5.6 2.9 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 KNE00135.1 - 0.49 10.5 33.3 0.95 9.5 8.3 3.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein She9_MDM33 PF05546.11 KNE00135.1 - 0.65 9.8 14.1 0.088 12.6 8.2 2.2 1 1 1 2 2 2 0 She9 / Mdm33 family DUF1664 PF07889.12 KNE00135.1 - 0.65 10.0 15.9 1.4 9.0 4.0 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) BST2 PF16716.5 KNE00135.1 - 0.68 10.6 27.7 0.39 11.3 8.5 3.2 3 1 0 3 3 3 0 Bone marrow stromal antigen 2 DUF1465 PF07323.12 KNE00135.1 - 0.82 9.5 10.1 0.26 11.1 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) Spc7 PF08317.11 KNE00135.1 - 0.87 8.4 35.5 0.075 11.9 11.0 2.3 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF3450 PF11932.8 KNE00135.1 - 1 8.6 23.6 0.11 11.8 9.9 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) YabA PF06156.13 KNE00135.1 - 1 10.0 22.1 1.7 9.4 9.1 2.9 2 1 1 3 3 3 0 Initiation control protein YabA UPF0242 PF06785.11 KNE00135.1 - 1.3 9.1 33.0 2.4 8.2 15.4 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1722 PF08349.11 KNE00135.1 - 1.4 9.2 9.3 0.99 9.7 0.3 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1722) Caldesmon PF02029.15 KNE00135.1 - 1.5 7.5 24.5 2.5 6.7 24.5 1.4 1 1 0 1 1 1 0 Caldesmon PDZ_4 PF17816.1 KNE00135.1 - 1.7 9.1 5.5 0.42 11.0 0.3 2.2 2 1 0 2 2 2 0 PDZ domain DUF2935 PF11155.8 KNE00135.1 - 1.7 9.0 7.9 3.6 7.9 1.8 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF2481 PF10654.9 KNE00135.1 - 1.9 8.5 6.7 0.44 10.5 0.9 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2481) IMD PF08397.11 KNE00135.1 - 2 7.8 15.8 0.33 10.3 5.8 2.3 2 0 0 2 2 2 0 IRSp53/MIM homology domain Plk4_PB2 PF18409.1 KNE00135.1 - 2 9.1 9.7 7.4 7.3 1.4 2.5 2 1 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 HrpB7 PF09486.10 KNE00135.1 - 2.1 8.8 19.3 3.9 7.8 5.4 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Flagellin_N PF00669.20 KNE00135.1 - 2.4 8.3 10.3 12 6.0 0.3 3.1 1 1 2 3 3 3 0 Bacterial flagellin N-terminal helical region Vfa1 PF08432.10 KNE00135.1 - 2.8 8.2 15.8 6 7.2 4.1 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Spore_II_R PF09551.10 KNE00135.1 - 2.8 8.4 14.8 0.14 12.6 4.3 2.5 2 1 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) YscO PF07321.12 KNE00135.1 - 3 7.8 32.7 4 7.4 15.6 2.5 2 1 0 2 2 2 0 Type III secretion protein YscO EMP24_GP25L PF01105.24 KNE00135.1 - 3.8 7.4 16.1 3.7 7.5 3.5 2.3 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DivIC PF04977.15 KNE00135.1 - 4 7.3 30.9 1.3 8.9 6.6 4.0 3 1 1 4 4 4 0 Septum formation initiator Laminin_II PF06009.12 KNE00135.1 - 4.6 7.3 18.7 3.2 7.8 3.2 2.4 3 0 0 3 3 2 0 Laminin Domain II DUF4337 PF14235.6 KNE00135.1 - 4.7 7.3 19.7 4.7 7.3 5.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) FlaC_arch PF05377.11 KNE00135.1 - 5.3 7.5 15.4 8.2 6.9 2.6 3.2 3 1 0 3 3 2 0 Flagella accessory protein C (FlaC) Spectrin PF00435.21 KNE00135.1 - 5.9 7.4 25.4 8.2 7.0 10.8 3.4 2 2 1 3 3 2 0 Spectrin repeat PspA_IM30 PF04012.12 KNE00135.1 - 6.8 6.2 29.8 63 3.0 29.8 2.2 1 1 0 1 1 1 0 PspA/IM30 family Uso1_p115_C PF04871.13 KNE00135.1 - 7 7.0 37.2 4 7.8 16.5 2.8 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-F_leu_zip PF10473.9 KNE00135.1 - 8.3 6.4 36.5 0.44 10.6 7.6 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.8 KNE00135.1 - 8.6 3.7 30.9 44 1.4 31.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) APG6_N PF17675.1 KNE00135.1 - 8.6 6.9 42.1 2.2 8.8 20.6 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Rotamase PF00639.21 KNE00135.1 - 9.2 7.3 12.5 4 8.5 2.4 2.7 3 0 0 3 3 2 0 PPIC-type PPIASE domain PEX11 PF05648.14 KNE00136.1 - 6.8e-06 25.7 0.2 6.8e-06 25.7 0.2 2.2 1 1 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) PRIMA1 PF16101.5 KNE00136.1 - 0.068 13.2 1.1 0.12 12.4 1.1 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Connexin PF00029.19 KNE00136.1 - 5 6.8 6.1 23 4.6 1.2 2.4 2 1 0 2 2 2 0 Connexin Dsl1_C PF11989.8 KNE00137.1 - 7.2e-16 58.5 0.4 7.2e-16 58.5 0.4 2.9 3 0 0 3 3 3 1 Retrograde transport protein Dsl1 C terminal Anillin_N PF16018.5 KNE00137.1 - 3.3 8.4 5.3 11 6.7 1.9 2.6 2 0 0 2 2 2 0 Anillin N-terminus DnaGprimase_HBD PF16730.5 KNE00137.1 - 3.3 7.8 7.6 0.43 10.7 0.8 2.9 3 0 0 3 3 3 0 DnaG-primase C-terminal, helicase-binding domain Fur_reg_FbpB PF13040.6 KNE00137.1 - 6.1 6.5 7.0 15 5.3 0.6 2.7 2 0 0 2 2 2 0 Fur-regulated basic protein B HMA PF00403.26 KNE00138.1 - 3.7e-11 43.3 0.2 4.3e-11 43.1 0.2 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Srg PF02118.21 KNE00139.1 - 0.23 11.1 0.1 0.27 10.8 0.1 1.0 1 0 0 1 1 1 0 Srg family chemoreceptor TB2_DP1_HVA22 PF03134.19 KNE00140.1 - 3.8e-08 33.2 4.9 5.7e-08 32.6 3.1 2.1 2 0 0 2 2 2 1 TB2/DP1, HVA22 family DUF3967 PF13152.6 KNE00140.1 - 0.8 9.5 3.4 0.96 9.3 2.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3967) Ribosomal_L23 PF00276.20 KNE00141.1 - 2.6e-08 34.1 0.0 5.9e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 RNA_pol_Rpb2_6 PF00562.28 KNE00142.1 - 4.8e-126 420.9 0.1 1.6e-125 419.3 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KNE00142.1 - 2.3e-68 229.7 0.0 3.5e-68 229.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KNE00142.1 - 5.4e-48 163.2 0.0 1.1e-47 162.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KNE00142.1 - 1.8e-34 118.0 0.2 4.1e-34 116.8 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 KNE00142.1 - 6.8e-25 87.1 0.7 1.6e-24 86.0 0.7 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KNE00142.1 - 2.4e-24 85.3 0.1 5.1e-24 84.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KNE00142.1 - 1.9e-23 82.8 0.7 6.1e-23 81.2 0.7 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 KNE00142.1 - 0.011 16.4 0.1 0.032 14.9 0.1 1.8 1 0 0 1 1 1 0 MRN-interacting protein RNA_pol_Rpb2_45 PF10385.9 KNE00142.1 - 0.24 11.7 0.8 3.3 8.1 0.2 2.5 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain Ribosomal_L13 PF00572.18 KNE00143.1 - 3.1e-46 156.7 0.3 4.7e-46 156.1 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 oligo_HPY PF08352.12 KNE00143.1 - 0.018 15.5 0.0 0.037 14.6 0.0 1.5 1 0 0 1 1 1 0 Oligopeptide/dipeptide transporter, C-terminal region SHS2_Rpb7-N PF03876.17 KNE00144.1 - 8.3e-17 61.3 0.0 1.4e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KNE00144.1 - 9.6e-17 61.1 0.1 1.4e-16 60.5 0.1 1.3 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 KNE00144.1 - 0.056 13.7 0.0 0.081 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 PINIT PF14324.6 KNE00145.1 - 7.4e-24 84.7 2.5 8.9e-23 81.2 0.0 3.4 3 0 0 3 3 3 1 PINIT domain zf-MIZ PF02891.20 KNE00145.1 - 1.4e-20 72.8 3.6 2.8e-20 71.8 3.6 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KNE00145.1 - 5.3e-11 42.2 2.2 6.6e-11 41.9 1.0 1.8 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 KNE00145.1 - 3.4e-06 26.6 2.8 6.3e-06 25.8 2.8 1.5 1 0 0 1 1 1 1 SAP domain zf-C3HC4_2 PF13923.6 KNE00145.1 - 0.029 14.2 3.0 0.065 13.1 3.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KNE00145.1 - 0.81 9.9 2.4 1.6 9.0 2.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING tRNA-synt_1d PF00750.19 KNE00146.1 - 5.8e-116 387.3 4.1 7.6e-116 386.9 4.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KNE00146.1 - 3.2e-27 95.1 0.3 7.1e-27 93.9 0.3 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KNE00146.1 - 0.00043 20.8 0.2 0.0015 19.1 0.0 2.1 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain POT1 PF02765.17 KNE00146.1 - 0.0049 16.7 0.2 0.023 14.6 0.0 2.1 3 0 0 3 3 3 1 Telomeric single stranded DNA binding POT1/CDC13 DUF4393 PF14337.6 KNE00146.1 - 0.057 13.2 0.4 0.24 11.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4393) UBA PF00627.31 KNE00148.1 - 4.8e-10 39.1 0.0 1.2e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain LPD38 PF18857.1 KNE00151.1 - 0.027 14.6 0.0 0.03 14.5 0.0 1.1 1 0 0 1 1 1 0 Large polyvalent protein associated domain 38 Equine_IAV_S2 PF06502.11 KNE00159.1 - 0.19 11.9 1.3 0.28 11.3 1.3 1.3 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein Lyase_1 PF00206.20 KNE00163.1 - 6.9e-24 84.8 0.0 1.1e-23 84.1 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KNE00163.1 - 3.6e-16 59.5 0.0 1.3e-15 57.6 0.0 2.0 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.11 KNE00163.1 - 0.061 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) GcnA_N PF18229.1 KNE00163.1 - 0.085 12.9 0.7 0.28 11.2 0.3 2.0 2 0 0 2 2 2 0 N-acetyl-beta-D-glucosaminidase N-terminal domain DASH_Dad3 PF08656.10 KNE00165.1 - 5.4e-21 74.4 2.3 7.2e-21 74.1 2.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad3 UPF0121 PF03661.13 KNE00166.1 - 0.015 14.7 15.6 0.062 12.7 10.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0121) WD40 PF00400.32 KNE00168.1 - 1.6e-20 73.0 10.0 9e-07 29.5 0.1 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNE00168.1 - 3e-10 40.3 0.0 1.6e-06 28.3 0.0 4.5 4 2 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KNE00168.1 - 0.01 14.2 0.0 0.029 12.7 0.0 1.6 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KNE00168.1 - 0.012 14.7 0.1 4.7 6.1 0.0 2.9 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 KNE00168.1 - 0.031 14.0 0.1 1.9 8.2 0.0 2.9 2 1 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain Cation_efflux PF01545.21 KNE00170.1 - 1.3e-21 77.2 17.7 1.8e-21 76.8 17.7 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KNE00170.1 - 2.1e-05 24.6 0.0 4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Zn_clus PF00172.18 KNE00171.1 - 1.5e-05 25.0 11.2 3e-05 24.0 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PGI PF00342.19 KNE00176.1 - 2.9e-240 797.9 5.1 3.4e-240 797.7 5.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF1892 PF08987.10 KNE00177.1 - 8.6e-14 51.7 1.6 8.6e-14 51.7 1.6 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1892) DUF4138 PF13595.6 KNE00177.1 - 0.044 13.0 0.0 0.055 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4138) P16-Arc PF04699.14 KNE00178.1 - 3.6e-44 150.8 0.0 4.2e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) AAA_23 PF13476.6 KNE00179.1 - 2.2e-05 25.1 2.2 0.00042 20.9 0.7 5.6 2 1 1 3 3 2 2 AAA domain AAA_22 PF13401.6 KNE00179.1 - 6.1e-05 23.3 0.0 6.1e-05 23.3 0.0 3.7 3 2 1 4 4 4 1 AAA domain T2SSE PF00437.20 KNE00179.1 - 0.00055 19.1 0.0 0.00055 19.1 0.0 2.9 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_5 PF07728.14 KNE00179.1 - 0.0038 17.2 0.9 0.55 10.2 0.0 3.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KNE00179.1 - 0.0081 15.7 0.0 0.028 13.9 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 KNE00179.1 - 0.011 15.9 0.9 0.085 13.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KNE00179.1 - 0.014 15.6 0.0 0.12 12.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 KNE00179.1 - 0.018 14.5 1.2 0.22 10.9 0.0 3.0 2 1 1 3 3 3 0 Poxvirus A32 protein CENP-H PF05837.12 KNE00179.1 - 0.018 15.4 9.4 0.018 15.4 9.4 6.1 1 1 5 6 6 6 0 Centromere protein H (CENP-H) TsaE PF02367.17 KNE00179.1 - 0.024 14.6 0.0 0.16 12.0 0.0 2.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 KNE00179.1 - 0.03 14.8 0.0 0.03 14.8 0.0 3.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 KNE00179.1 - 0.032 14.3 0.2 0.032 14.3 0.2 5.8 3 1 2 6 6 6 0 Helicase HerA, central domain TPR_MLP1_2 PF07926.12 KNE00179.1 - 0.041 14.0 86.9 0.04 14.0 24.3 5.1 2 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein AAA_16 PF13191.6 KNE00179.1 - 0.047 14.1 0.0 0.047 14.1 0.0 3.7 2 1 0 2 2 1 0 AAA ATPase domain AAA_29 PF13555.6 KNE00179.1 - 0.048 13.4 0.2 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KNE00179.1 - 0.056 14.0 0.0 0.056 14.0 0.0 4.3 2 1 1 3 3 2 0 ABC transporter RNA_helicase PF00910.22 KNE00179.1 - 0.078 13.4 0.1 0.56 10.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 KNE00179.1 - 0.087 12.9 0.0 0.087 12.9 0.0 3.5 3 2 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 KNE00179.1 - 0.099 12.0 0.0 0.099 12.0 0.0 2.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family CBP_BcsN PF17038.5 KNE00179.1 - 0.17 11.3 3.1 0.39 10.0 3.1 1.6 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsN AAA_18 PF13238.6 KNE00179.1 - 0.34 11.4 0.0 0.34 11.4 0.0 4.2 2 1 1 3 3 3 0 AAA domain GAS PF13851.6 KNE00179.1 - 0.4 10.0 89.0 0.38 10.1 9.0 5.4 1 1 5 6 6 6 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 KNE00179.1 - 0.45 10.0 69.4 1.7 8.1 26.9 3.8 1 1 2 3 3 3 0 Intermediate filament protein AAA_28 PF13521.6 KNE00179.1 - 0.48 10.7 0.0 0.48 10.7 0.0 2.9 3 1 1 4 4 4 0 AAA domain AAA_19 PF13245.6 KNE00179.1 - 0.74 10.1 9.0 0.14 12.4 4.0 2.6 1 1 1 2 2 2 0 AAA domain Spc7 PF08317.11 KNE00179.1 - 1.2 7.9 85.1 1.7 7.4 23.5 4.2 1 1 3 4 4 4 0 Spc7 kinetochore protein TEX12 PF15219.6 KNE00179.1 - 3 8.2 11.1 0.23 11.8 1.8 3.0 2 1 1 3 3 2 0 Testis-expressed 12 Aldo_ket_red PF00248.21 KNE00180.1 - 1.3e-48 165.7 0.0 1.8e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2380 PF09533.10 KNE00180.1 - 0.093 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) DUF2969 PF11184.8 KNE00180.1 - 0.11 12.9 0.0 0.33 11.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2969) TauD PF02668.16 KNE00181.1 - 4.3e-40 138.2 0.0 6.4e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KNE00181.1 - 2.6e-13 50.4 1.7 3.5e-13 50.0 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF971) RabGAP-TBC PF00566.18 KNE00183.1 - 5.9e-14 52.2 4.0 2.5e-13 50.2 4.0 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain WD40 PF00400.32 KNE00185.1 - 7.1e-13 48.8 9.8 0.038 14.9 0.2 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat NDK PF00334.19 KNE00187.1 - 2e-52 176.8 0.0 2.3e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Bcr-Abl_Oligo PF09036.10 KNE00188.1 - 0.051 13.6 0.9 0.071 13.1 0.9 1.3 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain ABC_tran PF00005.27 KNE00189.1 - 1.4e-17 64.5 0.0 3.7e-17 63.1 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KNE00189.1 - 2.8e-10 40.5 0.4 3.6e-05 23.7 0.6 2.5 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KNE00189.1 - 5.3e-05 22.8 1.0 0.21 11.0 0.0 2.9 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KNE00189.1 - 0.00043 20.2 0.1 0.00092 19.1 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 KNE00189.1 - 0.00063 20.3 1.8 0.0017 18.9 0.3 2.1 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KNE00189.1 - 0.0011 18.7 0.1 0.0022 17.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KNE00189.1 - 0.0011 18.7 0.0 0.0014 18.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KNE00189.1 - 0.0036 17.7 0.0 0.14 12.6 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KNE00189.1 - 0.0079 16.7 0.1 0.028 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KNE00189.1 - 0.02 14.5 0.0 0.043 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KNE00189.1 - 0.043 13.7 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 KNE00189.1 - 0.064 13.4 0.1 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KNE00189.1 - 0.086 13.1 0.2 0.93 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KNE00189.1 - 0.096 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_13 PF13166.6 KNE00189.1 - 0.1 11.3 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KNE00189.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 KNE00189.1 - 0.42 10.6 1.4 1.2 9.1 0.4 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MIF4G_like PF09088.11 KNE00190.1 - 3.1e-56 190.2 2.8 1.9e-55 187.6 0.6 2.4 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.11 KNE00190.1 - 1.2e-43 149.5 6.9 1.1e-41 143.0 6.9 2.5 1 1 0 1 1 1 1 MIF4G like DUF5377 PF17347.2 KNE00190.1 - 0.073 13.4 0.2 0.56 10.6 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5377) MIF4G PF02854.19 KNE00190.1 - 6.5 6.3 11.1 0.073 12.7 0.6 3.0 4 1 0 4 4 4 0 MIF4G domain S-methyl_trans PF02574.16 KNE00191.1 - 3.8e-64 217.1 0.0 4.3e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Ytp1 PF10355.9 KNE00193.1 - 5.4e-106 353.8 8.6 7.9e-106 353.3 8.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KNE00193.1 - 6.5e-23 80.5 6.6 6.5e-23 80.5 6.6 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Pkinase PF00069.25 KNE00196.1 - 1.2e-58 198.6 5.0 8.8e-42 143.3 0.4 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNE00196.1 - 5.9e-27 94.6 0.7 5.2e-21 75.1 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KNE00196.1 - 1.2e-05 24.5 0.2 2.2e-05 23.6 0.2 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KNE00196.1 - 0.001 18.5 1.2 0.0039 16.6 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KNE00196.1 - 0.0044 16.1 0.1 0.0082 15.2 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 KNE00196.1 - 0.0047 16.9 0.1 0.32 10.9 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KNE00196.1 - 0.02 14.2 0.3 0.064 12.6 0.0 1.9 2 0 0 2 2 2 0 Kinase-like eIF_4EBP PF05456.11 KNE00196.1 - 0.076 13.0 12.9 0.49 10.4 0.1 3.6 3 1 0 3 3 3 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF1087 PF06465.13 KNE00196.1 - 9.9 6.3 9.9 4.2 7.5 0.1 3.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1087) CCDC53 PF10152.9 KNE00198.1 - 1.4 9.3 11.4 4.2 7.8 11.3 1.8 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex SOG2 PF10428.9 KNE00198.1 - 3.5 6.7 16.4 4.3 6.4 16.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein zf-BED PF02892.15 KNE00200.1 - 7.4e-06 25.9 0.0 2.1e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 BED zinc finger Arc_trans_TRASH PF08394.10 KNE00200.1 - 0.017 15.4 0.6 0.032 14.5 0.6 1.4 1 0 0 1 1 1 0 Archaeal TRASH domain PyrI_C PF02748.15 KNE00200.1 - 0.21 11.6 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF4743 PF15916.5 KNE00203.1 - 5.6e-12 45.7 0.0 9.4e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 KNE00203.1 - 1.1e-07 31.9 0.0 5.3e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain Trypsin_2 PF13365.6 KNE00206.1 - 2.2e-16 61.1 0.1 5.3e-15 56.6 0.0 2.2 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 KNE00206.1 - 0.00023 21.1 0.0 0.00041 20.2 0.0 1.4 1 0 0 1 1 1 1 Trypsin TIP120 PF08623.10 KNE00210.1 - 0.22 11.3 4.5 0.21 11.3 4.5 1.1 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) Cecropin PF00272.19 KNE00210.1 - 0.72 9.6 7.0 0.72 9.6 2.6 2.3 2 0 0 2 2 2 0 Cecropin family Peptidase_S49_N PF08496.10 KNE00210.1 - 2.5 8.1 10.0 2.7 8.0 10.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Phage_tail_NK PF16532.5 KNE00213.1 - 0.069 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales Na_H_Exchanger PF00999.21 KNE00215.1 - 4.4e-62 210.1 37.5 6e-62 209.6 37.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Asp-B-Hydro_N PF05279.11 KNE00216.1 - 5.9 6.9 37.8 0.13 12.3 19.4 2.7 3 0 0 3 3 3 0 Aspartyl beta-hydroxylase N-terminal region SLATT_3 PF18184.1 KNE00217.1 - 0.82 9.8 3.1 1.2 9.3 0.7 2.2 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 NAD_binding_4 PF07993.12 KNE00218.1 - 5.7e-05 22.4 0.0 0.00023 20.4 0.0 1.7 1 1 1 2 2 2 1 Male sterility protein Epimerase PF01370.21 KNE00218.1 - 0.00051 19.6 0.0 0.00073 19.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KNE00218.1 - 0.00056 19.8 0.0 0.0039 17.1 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KNE00218.1 - 0.0094 15.0 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family E1-E2_ATPase PF00122.20 KNE00219.1 - 1.7e-49 167.8 0.1 1.7e-49 167.8 0.1 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KNE00219.1 - 4.9e-44 150.2 1.6 4.9e-44 150.2 1.6 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KNE00219.1 - 5.3e-25 88.9 0.0 1.4e-24 87.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KNE00219.1 - 8.1e-15 54.7 0.0 1.7e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KNE00219.1 - 6.6e-12 44.9 0.0 1.4e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KNE00219.1 - 3.1e-09 37.0 1.3 2.5e-06 27.4 1.5 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Sensor_TM1 PF13755.6 KNE00219.1 - 0.094 12.5 0.7 1.1 9.0 0.1 2.6 2 0 0 2 2 2 0 Sensor N-terminal transmembrane domain Sua5_yciO_yrdC PF01300.18 KNE00222.1 - 4.4e-53 179.4 0.0 6.6e-53 178.9 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KNE00222.1 - 2.9e-29 102.3 0.0 4.9e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding HEAT PF02985.22 KNE00223.1 - 0.00037 20.5 0.1 0.72 10.3 0.0 3.7 2 0 0 2 2 2 2 HEAT repeat Xpo1 PF08389.12 KNE00223.1 - 0.0013 18.8 0.1 0.082 13.0 0.0 3.5 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 KNE00223.1 - 0.0016 18.3 0.0 0.029 14.3 0.0 3.1 1 1 1 2 2 2 2 Importin-beta N-terminal domain FliG_N PF14842.6 KNE00223.1 - 0.054 14.1 0.0 0.2 12.2 0.0 2.0 1 0 0 1 1 1 0 FliG N-terminal domain PH_4 PF15404.6 KNE00226.1 - 8.8e-56 188.6 0.9 1.8e-52 177.8 0.4 3.4 2 1 0 2 2 2 1 Pleckstrin homology domain Spo7_2_N PF15407.6 KNE00226.1 - 3.8e-17 61.7 0.1 1.1e-16 60.2 0.1 1.9 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.29 KNE00226.1 - 0.00014 22.3 1.7 0.51 10.9 0.0 3.9 4 0 0 4 4 4 2 PH domain DIM1 PF02966.16 KNE00226.1 - 0.098 12.4 1.7 37 4.1 0.0 3.4 3 0 0 3 3 3 0 Mitosis protein DIM1 zf-RING_2 PF13639.6 KNE00227.1 - 0.014 15.7 0.5 0.031 14.6 0.5 1.6 1 0 0 1 1 1 0 Ring finger domain C1_1 PF00130.22 KNE00227.1 - 0.07 13.0 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 KNE00227.1 - 0.13 11.9 0.2 0.24 11.0 0.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KNE00227.1 - 0.24 11.3 0.7 0.49 10.3 0.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RNase_3_N PF18497.1 KNE00228.1 - 0.0039 17.4 0.1 0.0057 16.9 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease III N-terminal domain DUF5427 PF10310.9 KNE00229.1 - 3.6e-93 313.1 3.7 4.3e-93 312.8 3.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5427) DUF1687 PF07955.11 KNE00232.1 - 0.00084 19.8 0.1 0.0018 18.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) CN_hydrolase PF00795.22 KNE00233.1 - 8.1e-49 166.3 0.0 9.6e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase BCDHK_Adom3 PF10436.9 KNE00237.1 - 1.5e-59 200.4 0.0 2.8e-59 199.6 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KNE00237.1 - 1.9e-11 44.5 0.0 3.9e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peroxin-13_N PF04088.13 KNE00238.1 - 2.9e-51 173.6 1.1 4.6e-51 172.9 1.1 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 KNE00238.1 - 1.5e-06 27.8 0.0 3.8e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KNE00238.1 - 4.2e-06 26.3 0.0 7.6e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KNE00238.1 - 8.6e-06 25.5 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Pex2_Pex12 PF04757.14 KNE00238.1 - 0.0009 18.9 0.0 0.0016 18.1 0.0 1.4 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region SH3_3 PF08239.11 KNE00238.1 - 0.0085 16.3 0.1 0.017 15.4 0.1 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain DUF883 PF05957.13 KNE00239.1 - 3.6e-05 24.3 26.1 0.022 15.3 7.1 3.8 1 1 2 3 3 3 2 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 KNE00239.1 - 0.00011 22.1 19.4 0.0002 21.3 19.4 1.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 KNE00239.1 - 0.00038 20.9 34.8 0.84 10.2 6.0 4.2 1 1 1 2 2 2 1 YtxH-like protein Mitofilin PF09731.9 KNE00239.1 - 0.03 13.2 28.3 0.036 12.9 28.3 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ribosomal_L11_N PF03946.14 KNE00239.1 - 0.062 13.2 0.1 2.2 8.2 0.1 2.7 2 0 0 2 2 2 0 Ribosomal protein L11, N-terminal domain Prominin PF05478.11 KNE00239.1 - 0.19 9.7 7.3 0.25 9.2 7.3 1.2 1 0 0 1 1 1 0 Prominin KxDL PF10241.9 KNE00239.1 - 0.74 10.1 7.1 7.3 6.9 0.3 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein GARP PF16731.5 KNE00239.1 - 1.2 8.8 37.6 4.2 7.0 24.3 2.5 1 1 1 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma EspB PF05802.11 KNE00239.1 - 2.3 8.2 28.5 2.5 8.1 8.1 2.3 1 1 1 2 2 2 0 Enterobacterial EspB protein CdvA PF18822.1 KNE00239.1 - 3.1 7.7 16.1 1.7 8.5 1.6 3.6 1 1 3 4 4 4 0 CdvA-like coiled-coil domain ATP-synt_B PF00430.18 KNE00239.1 - 5.9 7.0 31.7 0.23 11.5 12.8 2.7 1 1 2 3 3 3 0 ATP synthase B/B' CF(0) XRN_M PF17846.1 KNE00239.1 - 6.6 5.6 10.7 8.5 5.2 10.7 1.2 1 0 0 1 1 1 0 Xrn1 helical domain CsbD PF05532.12 KNE00239.1 - 8.8 6.3 29.1 0.53 10.2 3.4 4.8 3 1 1 4 4 4 0 CsbD-like Pyr_redox_2 PF07992.14 KNE00240.1 - 1.5e-35 122.9 0.4 1.8e-35 122.6 0.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KNE00240.1 - 9.8e-12 45.3 1.1 2.6e-08 34.3 0.1 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KNE00240.1 - 1.8e-07 30.7 0.2 3.6e-07 29.7 0.2 1.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KNE00240.1 - 0.0011 18.9 0.6 1.4 8.9 0.0 3.4 4 0 0 4 4 4 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KNE00240.1 - 0.0023 17.3 0.0 0.15 11.4 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KNE00240.1 - 0.04 13.5 2.0 0.19 11.2 0.0 2.6 2 1 2 4 4 4 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 KNE00240.1 - 0.064 12.4 0.5 0.31 10.1 0.2 2.1 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KNE00240.1 - 0.073 11.8 0.6 9.6 4.8 0.1 2.7 3 0 0 3 3 3 0 HI0933-like protein DUF1398 PF07166.11 KNE00240.1 - 0.15 12.1 0.4 0.37 10.9 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) HMA PF00403.26 KNE00240.1 - 0.2 12.1 0.7 11 6.6 0.2 3.0 3 0 0 3 3 3 0 Heavy-metal-associated domain GIDA PF01134.22 KNE00240.1 - 1.1 8.3 4.9 6.1 5.8 0.1 3.2 4 0 0 4 4 4 0 Glucose inhibited division protein A Lipoprotein_Ltp PF07553.11 KNE00241.1 - 0.039 14.2 0.0 0.042 14.1 0.0 1.2 1 0 0 1 1 1 0 Host cell surface-exposed lipoprotein HAT_KAT11 PF08214.11 KNE00243.1 - 3.4e-75 253.5 0.0 4.3e-75 253.2 0.0 1.0 1 0 0 1 1 1 1 Histone acetylation protein AA_permease_2 PF13520.6 KNE00245.1 - 1.6e-48 165.6 47.6 2e-48 165.3 47.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KNE00245.1 - 8.8e-14 50.9 39.9 1.2e-13 50.5 39.9 1.1 1 0 0 1 1 1 1 Amino acid permease SieB PF14163.6 KNE00245.1 - 8.1 5.9 7.4 2.6 7.5 0.7 2.7 2 0 0 2 2 2 0 Super-infection exclusion protein B Pyridox_oxase_2 PF12766.7 KNE00246.1 - 2.6e-28 98.5 0.0 4.4e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 KNE00246.1 - 8.7e-06 25.8 0.0 2.1e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DHFR_1 PF00186.19 KNE00248.1 - 6.6e-28 97.4 0.0 8e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase DSPc PF00782.20 KNE00249.1 - 4e-12 46.1 0.1 4.7e-11 42.6 0.0 2.8 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KNE00249.1 - 0.057 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein-tyrosine phosphatase YqeY PF09424.10 KNE00251.1 - 1.8e-21 76.7 4.8 2.2e-21 76.5 4.8 1.1 1 0 0 1 1 1 1 Yqey-like protein Snf7 PF03357.21 KNE00251.1 - 0.027 14.1 3.8 0.039 13.5 3.8 1.3 1 1 0 1 1 1 0 Snf7 Tn7_Tnp_TnsA_C PF08721.11 KNE00251.1 - 0.043 14.5 0.2 0.15 12.7 0.0 2.0 1 1 0 2 2 2 0 TnsA endonuclease C terminal PP2C_C PF07830.13 KNE00251.1 - 0.28 11.6 3.4 5.5 7.5 0.2 2.6 2 1 1 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain FtsK_SpoIIIE PF01580.18 KNE00252.1 - 0.057 12.8 0.2 0.062 12.6 0.2 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family YEATS PF03366.16 KNE00254.1 - 1.3e-21 76.3 0.0 2.2e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KNE00254.1 - 1.8e-07 31.2 0.5 4e-07 30.1 0.5 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DNA_ligase_A_N PF04675.14 KNE00254.1 - 0.012 15.9 0.2 0.019 15.3 0.2 1.2 1 0 0 1 1 1 0 DNA ligase N terminus Neurokinin_B PF03823.14 KNE00254.1 - 0.17 11.9 0.0 0.52 10.4 0.0 1.8 2 0 0 2 2 2 0 Neurokinin B WD40 PF00400.32 KNE00255.1 - 4.3e-24 84.3 10.5 0.0013 19.5 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNE00255.1 - 7.5e-08 32.6 0.3 0.012 15.9 0.1 5.3 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KNE00255.1 - 0.00089 18.3 0.0 0.14 11.1 0.0 2.5 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KNE00255.1 - 0.022 13.5 0.2 1.6 7.4 0.0 2.7 2 1 0 2 2 2 0 Nup133 N terminal like TRF PF08558.10 KNE00256.1 - 2.7e-91 305.4 0.0 3.8e-91 304.9 0.0 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 KNE00256.1 - 6.1e-07 29.5 0.4 1.4e-06 28.4 0.4 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KNE00256.1 - 0.027 14.7 0.1 0.072 13.4 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Aminotran_3 PF00202.21 KNE00258.1 - 2.8e-105 352.3 0.0 3.3e-105 352.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KNE00258.1 - 0.007 15.6 0.0 0.012 14.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Mito_carr PF00153.27 KNE00259.1 - 7.6e-65 214.9 0.6 4.7e-23 80.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 KNE00259.1 - 0.6 10.2 4.0 5.8 7.1 0.2 2.6 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif B12D PF06522.11 KNE00260.1 - 2.6e-05 23.9 0.0 3.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Transcrip_reg PF01709.20 KNE00261.1 - 9.6e-71 238.0 3.6 1.1e-70 237.8 3.6 1.0 1 0 0 1 1 1 1 Transcriptional regulator OsmC PF02566.19 KNE00261.1 - 0.11 12.9 0.1 2 8.9 0.1 2.5 2 0 0 2 2 2 0 OsmC-like protein ATP-synt_F PF01990.17 KNE00262.1 - 8.9e-32 109.3 0.1 1e-31 109.1 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit ResIII PF04851.15 KNE00262.1 - 0.042 13.8 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit fn3_2 PF16893.5 KNE00263.1 - 1.1e-38 131.2 0.1 2.3e-38 130.2 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 KNE00263.1 - 5e-25 87.2 0.1 8.6e-25 86.4 0.1 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 KNE00263.1 - 1.2e-10 41.6 1.5 2.8e-10 40.4 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KNE00263.1 - 6.4e-06 26.0 0.0 1.4e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain DUF3006 PF11213.8 KNE00263.1 - 0.00075 19.7 0.8 0.0024 18.0 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 KNE00263.1 - 0.12 12.7 0.2 0.39 11.1 0.0 2.0 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain DUF3993 PF13158.6 KNE00263.1 - 0.13 12.5 0.4 0.28 11.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) DUF2606 PF10794.9 KNE00263.1 - 0.17 11.6 2.1 0.43 10.3 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Sds3 PF08598.11 KNE00264.1 - 5.6e-44 150.7 0.1 5.6e-44 150.7 0.1 1.9 2 0 0 2 2 2 1 Sds3-like PPPI_inhib PF14895.6 KNE00267.1 - 0.021 14.0 0.1 0.025 13.8 0.1 1.1 1 0 0 1 1 1 0 Protein phosphatase 1 inhibitor RRM_1 PF00076.22 KNE00268.1 - 1e-14 54.1 0.9 4.2e-10 39.3 0.1 3.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.6 KNE00268.1 - 0.042 13.5 0.0 0.17 11.6 0.0 2.0 1 0 0 1 1 1 0 Sporulation protein family 7 RRM_7 PF16367.5 KNE00268.1 - 0.053 13.6 0.0 2.1 8.5 0.0 2.9 2 0 0 2 2 2 0 RNA recognition motif Peptidase_C1_2 PF03051.15 KNE00269.1 - 1.3e-156 521.8 2.6 1.5e-156 521.6 2.6 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KNE00269.1 - 8.4e-06 26.0 1.2 0.002 18.3 0.9 2.6 2 1 0 2 2 2 2 Papain family cysteine protease DUF2258 PF10015.9 KNE00269.1 - 0.1 12.8 0.6 0.3 11.3 0.6 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) COG4 PF08318.12 KNE00270.1 - 1.6e-87 293.7 4.0 3.6e-87 292.6 4.0 1.6 1 0 0 1 1 1 1 COG4 transport protein Vps53_N PF04100.12 KNE00270.1 - 0.0044 16.0 1.4 0.015 14.3 1.4 1.9 1 0 0 1 1 1 1 Vps53-like, N-terminal L27_N PF09060.10 KNE00270.1 - 0.022 14.8 0.2 0.077 13.1 0.2 1.9 1 0 0 1 1 1 0 L27_N CdvA PF18822.1 KNE00270.1 - 0.42 10.5 0.0 0.42 10.5 0.0 3.2 3 0 0 3 3 3 0 CdvA-like coiled-coil domain zf_CCCH_4 PF18345.1 KNE00271.1 - 3.3e-15 55.5 28.6 1.2e-05 25.2 3.9 4.3 4 0 0 4 4 4 4 Zinc finger domain Torus PF16131.5 KNE00271.1 - 2.7e-11 44.1 18.7 0.0072 17.0 0.7 4.1 1 1 3 4 4 4 4 Torus domain zf-CCCH PF00642.24 KNE00271.1 - 3.9e-10 39.4 26.2 0.001 18.9 1.1 4.3 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KNE00271.1 - 6.8e-07 28.9 14.9 0.00096 18.9 0.9 3.8 3 0 0 3 3 3 3 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KNE00271.1 - 0.0022 18.2 14.9 0.077 13.2 6.8 2.5 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 KNE00271.1 - 0.048 14.1 24.7 1.5 9.4 3.4 4.8 4 1 0 4 4 4 0 RNA-binding, Nab2-type zinc finger FAD_binding_2 PF00890.24 KNE00272.1 - 3.2e-75 253.8 0.2 3.6e-75 253.6 0.2 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KNE00272.1 - 1.9e-11 44.2 0.6 9.7e-10 38.5 0.6 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KNE00272.1 - 1.4e-09 37.7 1.6 7e-08 32.1 0.7 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KNE00272.1 - 2.4e-08 33.8 0.8 5e-08 32.7 0.8 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KNE00272.1 - 1.3e-07 31.7 0.6 3.6e-07 30.3 0.1 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KNE00272.1 - 1.3e-06 27.5 4.8 0.0043 15.8 0.3 3.2 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 KNE00272.1 - 4.8e-05 22.6 0.3 0.00053 19.2 0.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KNE00272.1 - 0.00014 21.3 1.0 0.00024 20.5 0.5 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KNE00272.1 - 0.00014 22.4 0.3 0.0028 18.2 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KNE00272.1 - 0.00062 19.1 2.0 0.0038 16.5 0.6 2.2 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KNE00272.1 - 0.0011 18.1 0.1 0.0026 16.9 0.3 1.4 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KNE00272.1 - 0.052 12.8 0.2 1.6 7.9 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3939 PF13075.6 KNE00272.1 - 0.14 12.2 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3939) Mqo PF06039.15 KNE00272.1 - 0.15 10.6 0.0 1.8 7.0 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Amino_oxidase PF01593.24 KNE00272.1 - 0.15 11.3 0.2 0.25 10.6 0.2 1.4 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase GDI PF00996.18 KNE00272.1 - 0.16 10.5 0.0 0.65 8.4 0.0 1.8 2 0 0 2 2 2 0 GDP dissociation inhibitor Spo7 PF03907.13 KNE00273.1 - 9.9e-64 214.8 2.9 1.6e-63 214.1 2.9 1.3 1 0 0 1 1 1 1 Spo7-like protein DUF2157 PF09925.9 KNE00273.1 - 0.0025 17.6 0.4 0.0039 17.0 0.4 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2157) GWT1 PF06423.12 KNE00274.1 - 3.3e-37 127.9 8.1 7.5e-37 126.7 5.5 2.5 2 0 0 2 2 2 1 GWT1 Oxysterol_BP PF01237.18 KNE00275.1 - 6.3e-64 216.1 1.0 7.9e-62 209.2 1.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Ribosomal_L35Ae PF01247.18 KNE00276.1 - 1.2e-43 147.2 1.2 1.3e-43 147.0 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KNE00276.1 - 0.0043 17.2 0.1 3.6 7.9 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain GRAB PF10375.9 KNE00277.1 - 1.5e-06 27.8 2.6 3.2e-06 26.8 2.6 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Golgin_A5 PF09787.9 KNE00277.1 - 0.0078 15.7 26.3 0.0078 15.7 26.3 2.3 1 1 1 2 2 2 1 Golgin subfamily A member 5 DUF3450 PF11932.8 KNE00277.1 - 0.012 15.0 12.8 0.012 15.0 12.8 4.4 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) DUF3391 PF11871.8 KNE00277.1 - 0.022 15.3 2.1 0.022 15.3 2.1 3.9 1 1 1 2 2 1 0 Domain of unknown function (DUF3391) ZapB PF06005.12 KNE00277.1 - 0.025 15.0 3.3 0.025 15.0 3.3 6.5 2 1 2 4 4 2 0 Cell division protein ZapB Spc7 PF08317.11 KNE00277.1 - 0.16 10.8 62.0 0.83 8.5 15.2 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein T2SSG PF08334.11 KNE00277.1 - 0.42 10.7 3.8 2.7 8.1 0.6 2.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein G TMF_TATA_bd PF12325.8 KNE00277.1 - 0.73 10.1 57.3 0.26 11.5 8.1 4.3 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding KASH_CCD PF14662.6 KNE00277.1 - 1 9.2 64.4 0.14 12.0 41.0 4.1 1 1 2 3 3 2 0 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 KNE00277.1 - 1.3 9.2 65.4 2.3 8.4 37.5 3.3 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF2353 PF09789.9 KNE00277.1 - 1.3 8.3 48.5 0.016 14.6 27.5 2.3 1 1 1 2 2 1 0 Uncharacterized coiled-coil protein (DUF2353) Filament PF00038.21 KNE00277.1 - 1.5 8.4 58.1 0.45 10.0 21.8 3.1 1 1 2 3 3 3 0 Intermediate filament protein TACC_C PF05010.14 KNE00277.1 - 2 8.2 54.0 1.4 8.6 8.2 3.2 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF1664 PF07889.12 KNE00277.1 - 4.9 7.2 30.7 0.4 10.7 4.9 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) YabA PF06156.13 KNE00277.1 - 5.2 7.8 48.6 0.18 12.4 9.9 4.8 1 1 4 5 5 5 0 Initiation control protein YabA RFC1 PF08519.12 KNE00279.1 - 9e-54 181.9 0.8 1.9e-53 180.8 0.2 1.8 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.29 KNE00279.1 - 6.5e-11 42.8 0.0 2e-10 41.2 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KNE00279.1 - 1.3e-07 31.7 0.0 3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KNE00279.1 - 2.8e-05 24.6 2.2 5.5e-05 23.6 0.0 2.6 3 1 0 3 3 1 1 AAA ATPase domain RuvB_N PF05496.12 KNE00279.1 - 6.7e-05 22.7 0.0 0.0002 21.1 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 KNE00279.1 - 0.00052 19.8 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 KNE00279.1 - 0.00053 20.0 0.0 0.0015 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KNE00279.1 - 0.0016 18.6 0.0 0.0075 16.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KNE00279.1 - 0.0027 18.1 0.1 0.015 15.7 0.0 2.4 2 1 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 KNE00279.1 - 0.0046 17.2 0.1 0.04 14.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KNE00279.1 - 0.0056 17.2 0.0 0.0056 17.2 0.0 2.7 3 0 0 3 3 1 1 AAA domain AAA_29 PF13555.6 KNE00279.1 - 0.025 14.3 0.1 0.057 13.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.6 KNE00279.1 - 0.035 14.5 0.0 0.035 14.5 0.0 2.7 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.15 KNE00279.1 - 0.048 13.6 0.3 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 KNE00279.1 - 0.059 13.1 0.1 0.16 11.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_assoc_2 PF16193.5 KNE00279.1 - 0.061 13.7 1.5 0.097 13.0 0.0 2.1 2 0 0 2 2 1 0 AAA C-terminal domain NACHT PF05729.12 KNE00279.1 - 0.083 12.8 0.0 0.38 10.7 0.0 2.2 1 1 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 KNE00279.1 - 0.14 12.4 0.0 0.14 12.4 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.6 KNE00279.1 - 0.63 9.8 0.0 0.63 9.8 0.0 3.1 4 1 0 4 4 4 0 AAA domain Macoilin PF09726.9 KNE00279.1 - 6.6 5.2 10.8 15 4.0 10.8 1.5 1 0 0 1 1 1 0 Macoilin family CPSF100_C PF13299.6 KNE00279.1 - 7.2 6.8 8.6 2.5 8.3 3.4 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Pkinase PF00069.25 KNE00280.1 - 8.4e-71 238.4 0.0 1.1e-70 238.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE00280.1 - 1.1e-37 129.7 0.0 1.7e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNE00280.1 - 9.8e-06 25.1 0.3 3.1e-05 23.4 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 KNE00280.1 - 3.9e-05 22.9 0.1 5.9e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 KNE00280.1 - 0.0011 17.8 0.1 0.0016 17.3 0.1 1.3 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KNE00280.1 - 0.0015 18.5 0.6 0.0059 16.6 0.6 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KNE00280.1 - 0.0024 17.5 0.1 0.16 11.5 0.1 2.3 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KNE00280.1 - 0.015 14.3 0.3 0.025 13.5 0.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KNE00280.1 - 0.023 14.1 0.2 0.051 12.9 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MWFE PF15879.5 KNE00281.1 - 6e-21 74.4 0.7 8e-21 74.0 0.7 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit Nop53 PF07767.11 KNE00282.1 - 5e-74 250.1 43.2 5.8e-74 249.9 43.2 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) POC3_POC4 PF10448.9 KNE00284.1 - 4.4e-05 23.5 0.0 4.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 20S proteasome chaperone assembly proteins 3 and 4 PAC4 PF16093.5 KNE00284.1 - 7.8e-05 22.8 0.0 0.0001 22.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Albumin_I PF08027.11 KNE00285.1 - 0.82 9.3 4.9 0.17 11.5 1.2 1.8 2 0 0 2 2 2 0 Albumin I chain b RRM_1 PF00076.22 KNE00286.1 - 0.0025 17.6 0.9 0.57 10.0 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAM2 PF07145.15 KNE00286.1 - 1.5 8.7 4.2 0.88 9.4 0.5 2.5 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Nfu_N PF08712.11 KNE00287.1 - 1.4e-28 98.7 0.0 2.6e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KNE00287.1 - 4.8e-27 93.9 0.0 7.5e-27 93.3 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain SNF2_N PF00176.23 KNE00288.1 - 2.7e-56 190.8 0.1 4.5e-56 190.1 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KNE00288.1 - 9e-19 67.9 0.1 8.6e-17 61.5 0.1 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNE00288.1 - 6e-12 45.9 0.0 3e-11 43.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KNE00288.1 - 0.03 13.5 0.2 0.03 13.5 0.2 2.0 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase RCC1 PF00415.18 KNE00289.1 - 6.4e-25 87.5 11.4 0.0001 22.8 0.0 6.9 6 2 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KNE00289.1 - 1e-14 53.8 22.1 9.9e-08 31.6 0.1 5.8 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat DUF775 PF05603.12 KNE00290.1 - 3.5e-65 219.3 0.1 3.9e-65 219.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) DUF1722 PF08349.11 KNE00293.1 - 0.12 12.7 0.2 0.17 12.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) PI-TkoII_IV PF18714.1 KNE00296.1 - 0.062 12.8 0.0 0.062 12.8 0.0 1.0 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV Alb1 PF09135.11 KNE00297.1 - 2.2e-08 34.9 6.9 2.2e-08 34.9 6.9 1.6 1 1 0 1 1 1 1 Alb1 Ribul_P_3_epim PF00834.19 KNE00298.1 - 1.8e-65 220.0 0.0 2.1e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family MFS_1 PF07690.16 KNE00300.1 - 1.6e-25 89.8 20.9 1.6e-25 89.8 20.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KNE00300.1 - 0.00034 19.6 4.8 0.00034 19.6 4.8 3.0 2 2 0 2 2 2 1 Sugar (and other) transporter Ank_2 PF12796.7 KNE00301.1 - 2.2e-07 31.3 0.0 1e-06 29.2 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KNE00301.1 - 3.6e-07 30.3 0.0 0.015 15.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KNE00301.1 - 8.8e-06 25.7 0.0 0.083 13.5 0.0 3.1 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KNE00301.1 - 2.8e-05 24.6 0.0 0.025 15.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KNE00301.1 - 0.00038 20.7 0.1 0.12 12.7 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) HATPase_c_2 PF13581.6 KNE00301.1 - 0.048 13.6 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain A_deamin PF02137.18 KNE00302.1 - 1.7e-27 96.8 0.0 2.3e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Fis1_TPR_C PF14853.6 KNE00303.1 - 2.8e-23 81.7 0.3 6.1e-23 80.6 0.3 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KNE00303.1 - 5.7e-12 45.1 0.1 1.1e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KNE00303.1 - 0.0011 18.9 1.2 0.004 17.2 1.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KNE00303.1 - 0.0053 17.3 0.6 0.043 14.5 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KNE00303.1 - 0.1 13.1 0.8 0.58 10.7 0.3 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Alg6_Alg8 PF03155.15 KNE00304.1 - 4.5e-167 556.9 36.0 5.3e-167 556.6 36.0 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family TPP_enzyme_N PF02776.18 KNE00305.1 - 2.5e-25 89.1 0.0 4.7e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KNE00305.1 - 2.3e-21 76.0 0.1 1.2e-20 73.7 0.0 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KNE00305.1 - 1.4e-15 57.4 0.0 2.5e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF362 PF04015.12 KNE00305.1 - 0.025 14.8 0.0 0.062 13.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF362) CO_dh PF02552.16 KNE00305.1 - 0.037 13.8 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Fungal_trans PF04082.18 KNE00306.1 - 4.7e-30 104.5 4.8 4.7e-30 104.5 4.8 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNE00306.1 - 6.5e-10 39.0 7.9 1.1e-09 38.2 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aa_trans PF01490.18 KNE00307.1 - 1.9e-79 267.3 33.4 2.2e-79 267.1 33.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 KNE00307.1 - 2.8e-05 23.2 36.5 7.4e-05 21.7 36.5 1.6 1 1 0 1 1 1 1 Amino acid permease DNA_ligase_A_M PF01068.21 KNE00308.1 - 1.8e-43 148.6 0.6 4e-43 147.4 0.6 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KNE00308.1 - 7.7e-25 88.2 0.2 1.9e-24 86.9 0.2 1.8 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 KNE00308.1 - 5.5e-14 52.3 0.0 1.1e-05 25.7 0.0 2.8 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 KNE00308.1 - 3.1e-08 34.1 0.4 1.6e-07 31.8 0.1 2.3 2 0 0 2 2 2 1 RNA ligase BRCT PF00533.26 KNE00308.1 - 3.5e-07 30.5 0.0 0.00014 22.2 0.0 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C PF04679.15 KNE00308.1 - 2e-06 28.3 0.0 6.8e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.19 KNE00308.1 - 5.1e-06 26.5 0.9 0.016 15.1 0.0 2.5 2 0 0 2 2 2 2 mRNA capping enzyme, catalytic domain DUF4401 PF14351.6 KNE00309.1 - 0.012 14.9 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) DUF1752 PF08550.10 KNE00312.1 - 2.4e-05 24.0 0.4 5.7e-05 22.9 0.4 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Pol_alpha_B_N PF08418.10 KNE00318.1 - 0.0034 17.4 0.1 0.0036 17.3 0.1 1.0 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Helicase_C PF00271.31 KNE00319.1 - 2.6e-20 72.8 1.7 2.2e-18 66.6 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNE00319.1 - 3.5e-19 69.5 0.0 3.5e-19 69.5 0.0 3.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KNE00319.1 - 7e-19 68.3 0.0 9.6e-16 58.0 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KNE00319.1 - 0.00041 20.1 0.0 0.0016 18.2 0.0 2.0 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 KNE00319.1 - 0.046 14.0 0.0 0.38 11.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KNE00319.1 - 0.14 11.9 0.0 11 5.8 0.0 2.8 2 1 0 2 2 2 0 IstB-like ATP binding protein Pre-PUA PF17832.1 KNE00321.1 - 7.5e-22 77.8 0.5 1.1e-21 77.3 0.5 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KNE00321.1 - 1.1e-18 66.9 0.1 1.8e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 KNE00321.1 - 0.0065 16.8 1.8 0.0076 16.5 0.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1947) CAP_GLY PF01302.25 KNE00322.1 - 4.1e-16 58.7 0.1 8.5e-16 57.7 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 KNE00322.1 - 1.6e-15 56.9 1.9 0.00088 19.6 0.1 5.5 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KNE00322.1 - 2.7e-05 23.8 7.5 0.098 12.4 1.3 4.4 3 2 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 KNE00322.1 - 0.00024 20.9 1.2 30 5.0 0.0 5.2 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 KNE00322.1 - 0.00024 21.2 14.5 9.5 7.2 0.3 7.2 5 2 1 6 6 6 1 Leucine Rich Repeat Ubiquitin_2 PF14560.6 KNE00322.1 - 0.00028 21.3 0.0 0.00061 20.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_9 PF14580.6 KNE00322.1 - 0.0071 15.9 1.9 0.2 11.2 0.2 3.0 1 1 2 3 3 3 1 Leucine-rich repeat ubiquitin PF00240.23 KNE00322.1 - 0.12 12.2 0.0 0.35 10.6 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin family GN3L_Grn1 PF08701.11 KNE00323.1 - 1.1e-22 79.9 16.1 2.7e-22 78.7 16.1 1.7 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KNE00323.1 - 1.4e-19 70.3 0.5 2e-15 56.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KNE00323.1 - 7.7e-11 41.8 0.3 2.6e-09 36.8 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KNE00323.1 - 3e-05 24.0 0.2 0.0011 18.9 0.2 2.4 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 KNE00323.1 - 0.00025 20.7 0.0 0.046 13.3 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KNE00323.1 - 0.00026 21.1 5.4 0.52 10.4 0.0 3.8 2 2 1 3 3 3 2 Dynamin family MeaB PF03308.16 KNE00323.1 - 0.019 14.0 1.7 0.021 13.8 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KNE00323.1 - 0.028 14.0 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KNE00323.1 - 0.033 14.7 0.9 0.083 13.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain TniB PF05621.11 KNE00323.1 - 0.071 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 KNE00323.1 - 0.1 12.8 0.0 3.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF3347 PF11827.8 KNE00323.1 - 0.11 12.6 6.7 0.24 11.5 6.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) YL1 PF05764.13 KNE00324.1 - 0.0014 18.9 3.3 0.0016 18.6 3.3 1.1 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 KNE00324.1 - 0.0067 14.8 0.2 0.0067 14.8 0.2 1.1 1 0 0 1 1 1 1 CDC45-like protein Cwf_Cwc_15 PF04889.12 KNE00324.1 - 0.014 15.2 6.5 0.015 15.0 6.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KNE00324.1 - 0.029 12.6 4.0 0.03 12.5 4.0 1.2 1 0 0 1 1 1 0 Nop14-like family CmlA_N PF18456.1 KNE00324.1 - 0.031 13.6 0.1 0.042 13.1 0.1 1.1 1 0 0 1 1 1 0 Diiron non-heme beta-hydroxylase N-terminal domain Sporozoite_P67 PF05642.11 KNE00324.1 - 0.034 12.2 1.7 0.039 12.1 1.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.12 KNE00324.1 - 0.043 13.1 8.6 0.049 13.0 8.6 1.1 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 KNE00324.1 - 0.061 13.4 2.8 0.077 13.0 2.8 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP1_TM PF14812.6 KNE00324.1 - 0.15 12.5 8.3 0.34 11.3 8.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.13 KNE00324.1 - 0.22 11.4 3.5 0.26 11.1 3.5 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2076 PF09849.9 KNE00324.1 - 0.29 11.2 3.9 0.37 10.8 3.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DASH_Dad2 PF08654.10 KNE00324.1 - 0.56 10.7 2.1 0.89 10.0 2.1 1.4 1 1 0 1 1 1 0 DASH complex subunit Dad2 MFMR_assoc PF16596.5 KNE00324.1 - 2 8.9 6.0 3.2 8.2 6.0 1.3 1 0 0 1 1 1 0 Disordered region downstream of MFMR GDA1_CD39 PF01150.17 KNE00325.1 - 3.8e-125 417.9 0.1 5.5e-125 417.4 0.1 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF5355 PF17306.2 KNE00326.1 - 1.4e-83 280.7 3.7 1.9e-83 280.3 3.7 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5355) BRO1 PF03097.18 KNE00326.1 - 0.00021 20.2 0.4 0.00076 18.4 0.1 2.0 2 1 0 2 2 2 1 BRO1-like domain Unstab_antitox PF09720.10 KNE00326.1 - 0.51 10.4 2.2 1.1 9.3 2.2 1.5 1 0 0 1 1 1 0 Putative addiction module component EF1_GNE PF00736.19 KNE00327.1 - 2.6e-20 72.4 0.1 2.8e-20 72.3 0.1 1.0 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain N6-adenineMlase PF10237.9 KNE00329.1 - 2e-50 170.7 0.0 2.7e-50 170.3 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase B-block_TFIIIC PF04182.12 KNE00330.1 - 2.4e-11 43.6 0.2 8.4e-10 38.7 0.0 3.1 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC HTH_24 PF13412.6 KNE00330.1 - 0.041 13.5 0.3 0.21 11.2 0.2 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_12 PF08461.10 KNE00330.1 - 0.041 13.8 0.3 0.22 11.5 0.1 2.4 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain ABC_tran_CTD PF16326.5 KNE00330.1 - 0.37 11.1 3.3 1.2 9.4 0.1 2.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain G-patch PF01585.23 KNE00331.1 - 1.1e-12 47.6 0.2 2.6e-12 46.4 0.2 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KNE00331.1 - 0.00057 19.9 0.1 0.00057 19.9 0.1 3.6 2 1 0 2 2 2 1 G-patch domain Glyco_hydro_72 PF03198.14 KNE00332.1 - 1.9e-136 454.5 10.3 2.5e-136 454.0 10.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KNE00332.1 - 8.2e-25 87.3 4.3 3.1e-24 85.4 4.3 2.1 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 KNE00332.1 - 0.00019 21.0 0.9 0.0074 15.8 0.9 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KNE00332.1 - 0.00031 19.9 3.7 0.00058 19.1 3.7 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF3454 PF11936.8 KNE00334.1 - 0.016 15.6 0.0 0.047 14.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3454) Latexin PF06907.12 KNE00334.1 - 0.09 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Latexin Trypan_PARP PF05887.11 KNE00335.1 - 0.00041 20.3 14.1 0.00044 20.2 14.1 1.1 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.13 KNE00335.1 - 0.36 9.3 6.3 0.37 9.2 6.3 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein TonB_N PF16031.5 KNE00335.1 - 8.8 6.9 19.1 13 6.3 19.1 1.4 1 1 0 1 1 1 0 TonB polyproline region Gsf2 PF11055.8 KNE00338.1 - 1.8e-135 451.5 0.1 2.1e-135 451.3 0.1 1.0 1 0 0 1 1 1 1 Glucose signalling factor 2 Sad1_UNC PF07738.13 KNE00338.1 - 0.12 12.4 0.0 0.68 9.9 0.0 2.1 2 0 0 2 2 2 0 Sad1 / UNC-like C-terminal Meth_synt_2 PF01717.18 KNE00339.1 - 1.9e-151 503.9 0.0 2.2e-147 490.6 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KNE00339.1 - 2.8e-118 395.0 0.1 7.1e-112 374.0 0.0 2.6 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.9 KNE00339.1 - 1.9 8.3 4.7 0.84 9.5 0.1 2.9 3 0 0 3 3 3 0 Short C-terminal domain Ank_4 PF13637.6 KNE00340.1 - 0.21 12.2 0.0 0.25 12.0 0.0 1.2 1 1 0 1 1 1 0 Ankyrin repeats (many copies) SEP PF08059.13 KNE00341.1 - 9.4e-25 87.0 0.3 3.6e-24 85.1 0.0 2.1 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 KNE00341.1 - 7.5e-15 54.9 0.0 1.6e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KNE00341.1 - 1.8e-10 40.5 0.7 3.6e-10 39.5 0.7 1.6 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 KNE00341.1 - 0.0066 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 TAP C-terminal domain RNB PF00773.19 KNE00342.1 - 0.047 13.0 0.0 0.16 11.3 0.0 2.0 1 1 0 1 1 1 0 RNB domain Chorismate_bind PF00425.18 KNE00343.1 - 1.1e-92 310.2 0.0 1.6e-92 309.8 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme DUF2312 PF10073.9 KNE00343.1 - 0.021 14.5 0.1 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) POR PF01558.18 KNE00343.1 - 0.022 14.8 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Anth_synt_I_N PF04715.13 KNE00343.1 - 0.041 14.1 3.3 16 5.7 0.2 3.5 2 1 0 2 2 2 0 Anthranilate synthase component I, N terminal region Myb_DNA-bind_6 PF13921.6 KNE00344.1 - 1.9e-10 40.8 1.2 2e-09 37.5 0.2 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KNE00344.1 - 8.2e-10 38.7 2.3 4.5e-08 33.1 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain AvrPphF-ORF-2 PF09143.10 KNE00344.1 - 0.093 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 AvrPphF-ORF-2 PTH2 PF01981.16 KNE00345.1 - 1e-40 138.7 0.0 1.3e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 U62_UL91 PF17442.2 KNE00346.1 - 0.0003 20.7 0.5 0.038 14.0 0.0 3.0 2 0 0 2 2 2 1 Functional domain of U62 and UL91 proteins UvrA_inter PF17760.1 KNE00346.1 - 0.0026 17.8 1.2 0.0026 17.8 1.2 2.0 2 0 0 2 2 2 1 UvrA interaction domain PMEI PF04043.15 KNE00346.1 - 0.31 11.4 0.1 0.31 11.4 0.1 2.5 3 0 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor Collectrin PF16959.5 KNE00346.1 - 0.6 9.9 2.9 0.55 10.0 0.1 2.3 2 0 0 2 2 2 0 Renal amino acid transporter DUF1798 PF08807.10 KNE00347.1 - 0.0011 19.0 5.4 0.17 12.0 0.5 2.4 1 1 1 2 2 2 2 Bacterial domain of unknown function (DUF1798) Apolipoprotein PF01442.18 KNE00347.1 - 0.0033 17.3 0.1 0.014 15.2 0.1 1.9 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 KNE00347.1 - 0.067 13.7 0.6 0.12 13.0 0.6 1.6 1 1 0 1 1 1 0 YtxH-like protein SMI1_KNR4 PF09346.10 KNE00348.1 - 9.7e-37 126.3 0.0 2.3e-36 125.1 0.0 1.7 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) DIE2_ALG10 PF04922.12 KNE00349.1 - 5.9e-102 341.9 34.7 5.9e-102 341.9 34.7 1.9 2 1 0 2 2 2 1 DIE2/ALG10 family PNTB_4TM PF12769.7 KNE00349.1 - 3.5 8.2 6.8 5.5 7.5 0.0 3.6 4 0 0 4 4 4 0 4TM region of pyridine nucleotide transhydrogenase, mitoch PQQ_3 PF13570.6 KNE00350.1 - 0.011 16.2 0.1 0.23 12.0 0.0 2.7 3 0 0 3 3 3 0 PQQ-like domain DUF1057 PF06342.12 KNE00352.1 - 0.059 12.4 0.0 0.059 12.4 0.0 1.0 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Gtr1_RagA PF04670.12 KNE00353.1 - 3.1e-68 229.6 0.3 4.4e-68 229.1 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 KNE00353.1 - 0.029 14.4 0.0 0.065 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KNE00353.1 - 0.098 11.8 0.0 0.24 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) adh_short_C2 PF13561.6 KNE00358.1 - 1.4e-53 181.9 1.4 2.4e-53 181.1 1.4 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNE00358.1 - 2.2e-38 131.7 1.6 5.5e-38 130.4 1.6 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KNE00358.1 - 1.9e-06 27.9 0.2 2.8e-06 27.4 0.2 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KNE00358.1 - 0.004 17.0 0.2 0.006 16.5 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KNE00358.1 - 0.016 14.3 0.3 0.04 13.0 0.1 1.7 2 1 0 2 2 2 0 RmlD substrate binding domain DFP PF04127.15 KNE00358.1 - 0.11 12.3 0.1 0.26 11.1 0.1 1.6 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Epimerase PF01370.21 KNE00358.1 - 0.11 11.9 0.2 0.34 10.3 0.2 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 KNE00363.1 - 4.1e-42 144.4 28.3 4.1e-42 144.4 28.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FPN1 PF06963.12 KNE00363.1 - 0.0042 15.7 0.1 0.0042 15.7 0.1 1.7 2 0 0 2 2 2 1 Ferroportin1 (FPN1) FA_hydroxylase PF04116.13 KNE00365.1 - 1.3e-07 32.0 8.6 1.5e-07 31.9 8.6 1.0 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily MMgT PF10270.9 KNE00366.1 - 1.5e-19 70.1 0.0 2.2e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Membrane magnesium transporter Glyco_hydro_15 PF00723.21 KNE00367.1 - 2.2e-56 191.5 0.0 3e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Sialidase PF02973.16 KNE00368.1 - 0.089 12.3 0.0 0.093 12.2 0.0 1.0 1 0 0 1 1 1 0 Sialidase, N-terminal domain SNF2_N PF00176.23 KNE00369.1 - 9.1e-62 208.8 0.1 9.1e-62 208.8 0.1 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KNE00369.1 - 1.5e-20 73.6 0.0 4.6e-20 72.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNE00369.1 - 4.7e-08 33.2 2.7 2.7e-07 30.8 0.0 3.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Pro_CA PF00484.19 KNE00373.1 - 1.2e-41 142.6 0.0 1.5e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Lysine_decarbox PF03641.14 KNE00375.1 - 5.7e-39 133.2 0.0 7.1e-39 132.9 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KNE00375.1 - 1.8e-14 53.6 0.0 3.1e-14 52.9 0.0 1.5 1 1 0 1 1 1 1 SLOG cluster4 family SNARE PF05739.19 KNE00378.1 - 2.9e-05 24.0 0.1 5.4e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 SNARE domain Vps55 PF04133.14 KNE00379.1 - 4.5e-37 126.6 5.7 5.1e-37 126.4 5.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF2157 PF09925.9 KNE00379.1 - 0.0051 16.6 2.4 0.0069 16.2 2.4 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2157) Wzy_C PF04932.15 KNE00379.1 - 1 9.0 8.0 1 9.0 0.1 2.1 2 0 0 2 2 2 0 O-Antigen ligase MPM1 PF17234.2 KNE00380.1 - 9.3e-50 169.2 1.4 1.4e-49 168.7 1.4 1.3 1 0 0 1 1 1 1 Mitochondrial peculiar membrane protein 1 Spc29 PF17082.5 KNE00380.1 - 0.098 12.5 1.8 0.25 11.1 0.4 2.1 1 1 1 2 2 2 0 Spindle Pole Component 29 tRNA-synt_1c PF00749.21 KNE00382.1 - 2.4e-100 335.5 0.0 3e-100 335.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain SMC_N PF02463.19 KNE00383.1 - 1.2e-23 83.7 3.5 2.5e-23 82.7 3.5 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KNE00383.1 - 4.1e-13 50.3 28.0 4.1e-13 50.3 28.0 6.3 2 2 1 3 3 2 1 AAA domain AAA_15 PF13175.6 KNE00383.1 - 2.2e-08 34.2 18.7 2.2e-08 34.2 18.7 3.4 2 1 1 3 3 2 1 AAA ATPase domain AAA_29 PF13555.6 KNE00383.1 - 0.0013 18.4 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KNE00383.1 - 0.0028 17.5 15.5 0.018 14.9 0.2 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF812 PF05667.11 KNE00383.1 - 0.0029 16.6 5.9 0.0029 16.6 5.9 4.3 2 2 2 4 4 3 1 Protein of unknown function (DUF812) AAA PF00004.29 KNE00383.1 - 0.029 14.8 9.9 0.059 13.8 0.1 3.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 KNE00383.1 - 0.035 13.7 0.0 0.035 13.7 0.0 4.7 3 2 1 5 5 5 0 AAA domain LPP PF04728.13 KNE00383.1 - 0.066 13.6 0.3 0.066 13.6 0.3 6.4 8 1 0 8 8 8 0 Lipoprotein leucine-zipper AAA_33 PF13671.6 KNE00383.1 - 0.067 13.4 0.7 0.34 11.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KNE00383.1 - 0.11 13.0 0.1 0.11 13.0 0.1 4.6 3 1 0 3 3 2 0 ABC transporter RNA_helicase PF00910.22 KNE00383.1 - 0.28 11.6 1.2 0.89 10.0 0.1 2.6 3 0 0 3 3 2 0 RNA helicase SR-25 PF10500.9 KNE00385.1 - 0.5 9.9 8.4 0.44 10.1 8.4 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein eRF1_1 PF03463.15 KNE00387.1 - 1.8e-37 128.2 1.5 3.3e-37 127.4 1.5 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 KNE00387.1 - 2.1e-25 89.6 0.2 3.3e-25 88.9 0.2 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KNE00387.1 - 2.7e-22 79.4 0.4 1.5e-21 77.0 0.0 2.4 3 0 0 3 3 3 1 eRF1 domain 3 Methyltransf_15 PF09445.10 KNE00388.1 - 1.4e-45 154.8 0.0 1.9e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KNE00388.1 - 4e-09 37.1 0.0 1.4e-08 35.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNE00388.1 - 1.3e-07 31.5 0.0 1.9e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNE00388.1 - 4.1e-06 27.4 0.1 1.4e-05 25.6 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNE00388.1 - 1.1e-05 25.3 0.0 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 KNE00388.1 - 0.00024 20.9 0.0 0.00048 19.9 0.0 1.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 KNE00388.1 - 0.00031 20.1 0.0 0.00048 19.5 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_12 PF08242.12 KNE00388.1 - 0.00062 20.5 0.0 0.0021 18.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KNE00388.1 - 0.0012 18.3 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Pox_MCEL PF03291.16 KNE00388.1 - 0.0022 17.2 0.0 0.0032 16.6 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme tRNA_U5-meth_tr PF05958.11 KNE00388.1 - 0.0027 16.7 0.0 0.004 16.2 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Cons_hypoth95 PF03602.15 KNE00388.1 - 0.0031 17.2 0.0 0.005 16.5 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 CMAS PF02353.20 KNE00388.1 - 0.0044 16.4 0.0 0.0068 15.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KNE00388.1 - 0.014 15.0 0.0 0.039 13.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KNE00388.1 - 0.027 14.0 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase SepF PF04472.12 KNE00388.1 - 0.17 12.2 0.0 0.59 10.5 0.0 1.9 2 0 0 2 2 2 0 Cell division protein SepF tRNA_bind PF01588.20 KNE00389.1 - 4.7e-27 93.9 0.0 9.7e-27 92.9 0.0 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_6 PF17171.4 KNE00389.1 - 0.021 14.6 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF2201_N PF13203.6 KNE00389.1 - 0.046 13.3 6.6 0.068 12.8 6.6 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain SR-25 PF10500.9 KNE00389.1 - 0.069 12.7 14.0 0.1 12.2 14.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2894 PF11445.8 KNE00389.1 - 0.69 10.4 6.3 1.2 9.5 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) DUF3807 PF12720.7 KNE00389.1 - 0.91 9.8 11.0 1.7 8.9 11.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Neur_chan_memb PF02932.16 KNE00389.1 - 0.94 9.5 2.7 1.5 8.8 2.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 KNE00389.1 - 0.95 7.7 7.1 1.2 7.3 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KNE00389.1 - 2.2 7.0 6.5 2.9 6.5 6.5 1.1 1 0 0 1 1 1 0 Presenilin Med3 PF11593.8 KNE00389.1 - 2.2 7.4 10.7 0.99 8.5 8.4 1.5 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF4554 PF15091.6 KNE00389.1 - 3.4 6.5 6.4 4.8 6.0 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Hid1 PF12722.7 KNE00389.1 - 3.5 5.6 5.6 4.7 5.2 5.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NPR3 PF03666.13 KNE00389.1 - 4.3 6.0 8.4 6.2 5.5 8.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.12 KNE00389.1 - 6.7 6.4 18.2 11 5.7 18.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GFO_IDH_MocA PF01408.22 KNE00390.1 - 2e-21 77.0 0.9 4.3e-21 75.9 0.4 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KNE00390.1 - 3.8e-06 27.5 0.3 6.1e-06 26.9 0.3 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KNE00390.1 - 0.00059 20.4 0.0 0.0014 19.1 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 KNE00390.1 - 0.055 13.9 0.1 0.14 12.6 0.1 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain PhyH PF05721.13 KNE00391.1 - 5.8e-15 56.1 0.0 1.4e-14 54.9 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PAS PF00989.25 KNE00393.1 - 1.1e-05 25.4 0.0 2.2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold Ser_hydrolase PF06821.13 KNE00393.1 - 0.038 13.8 0.4 0.08 12.8 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase Sugar_tr PF00083.24 KNE00394.1 - 2.8e-92 310.0 19.7 3.5e-92 309.6 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNE00394.1 - 1.2e-29 103.4 26.9 1.6e-21 76.6 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KNE00394.1 - 2.2e-06 26.4 15.0 9.1e-05 21.1 2.1 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KNE00394.1 - 4.4e-05 22.9 5.6 4.4e-05 22.9 5.6 2.8 2 2 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB SPC12 PF06645.13 KNE00394.1 - 3.5 7.8 10.3 5.5 7.2 1.5 4.0 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Ribosomal_L27A PF00828.19 KNE00395.1 - 3.4e-22 79.5 0.1 5.4e-22 78.8 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Spem1 PF15670.5 KNE00395.1 - 0.16 11.5 0.1 0.38 10.3 0.1 1.6 1 1 0 1 1 1 0 Spermatid maturation protein 1 HD_3 PF13023.6 KNE00396.1 - 4.5e-39 134.0 0.0 5.9e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KNE00396.1 - 2.4e-08 33.9 0.0 3.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KNE00396.1 - 9.4e-06 25.9 0.0 1.5e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 HD domain Evr1_Alr PF04777.13 KNE00399.1 - 2.7e-32 111.2 3.4 3.7e-32 110.8 3.4 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin_2 PF13098.6 KNE00400.1 - 6.5e-06 26.6 0.0 1.2e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KNE00400.1 - 0.0028 18.0 0.1 0.033 14.5 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin PF00085.20 KNE00400.1 - 0.0031 17.5 0.0 0.0042 17.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Mito_carr PF00153.27 KNE00401.1 - 1.1e-51 172.7 4.7 5.7e-17 61.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tox-GHH PF15636.6 KNE00404.1 - 0.023 14.7 0.2 0.023 14.7 0.2 1.1 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Pkinase PF00069.25 KNE00407.1 - 8.1e-46 156.5 0.0 1.7e-45 155.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE00407.1 - 5e-27 94.8 0.0 8.7e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase COX4 PF02936.14 KNE00409.1 - 1.4e-34 119.1 0.1 2.3e-34 118.4 0.1 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase subunit IV DctP PF03480.13 KNE00409.1 - 0.054 12.8 0.1 0.081 12.3 0.1 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 UvrA_DNA-bind PF17755.1 KNE00409.1 - 0.11 12.9 0.1 0.69 10.3 0.1 2.2 1 1 1 2 2 2 0 UvrA DNA-binding domain Sec3_C PF09763.9 KNE00410.1 - 8.3e-113 378.2 29.6 1.6e-112 377.2 29.6 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KNE00410.1 - 8.9e-15 54.6 0.3 7.9e-14 51.6 0.0 2.7 3 0 0 3 3 3 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Baculo_PEP_C PF04513.12 KNE00410.1 - 0.065 13.3 4.6 0.21 11.6 0.3 3.8 2 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2120 PF09893.9 KNE00410.1 - 1.2 9.3 6.8 0.37 10.9 0.3 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) Sec66 PF09802.9 KNE00411.1 - 4e-59 199.2 0.7 5.2e-59 198.8 0.7 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 SieB PF14163.6 KNE00411.1 - 0.013 15.0 1.5 0.02 14.4 0.1 2.0 2 0 0 2 2 2 0 Super-infection exclusion protein B HLH PF00010.26 KNE00411.1 - 0.07 13.1 0.3 0.23 11.4 0.3 2.0 1 1 0 1 1 1 0 Helix-loop-helix DNA-binding domain Oxidored_q2 PF00420.24 KNE00411.1 - 0.097 12.3 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L R2K_3 PF14243.6 KNE00411.1 - 0.11 12.5 0.3 0.55 10.2 0.1 1.9 1 1 1 2 2 2 0 ATP-grasp domain, R2K clade family 3 Arf PF00025.21 KNE00414.1 - 6.2e-38 130.0 0.1 2.2e-30 105.4 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 KNE00414.1 - 1.3e-11 44.3 0.0 3.5e-05 23.1 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KNE00414.1 - 1.2e-10 41.6 0.0 2.2e-08 34.3 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KNE00414.1 - 1.2e-09 38.0 0.0 6.1e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 Ras family SRPRB PF09439.10 KNE00414.1 - 3e-08 33.3 0.0 2.7e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KNE00414.1 - 3.3e-05 23.4 0.0 0.00035 20.0 0.0 2.0 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KNE00414.1 - 0.00027 21.0 0.0 0.0024 17.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KNE00414.1 - 0.0005 19.6 0.0 0.0012 18.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF1704 PF08014.11 KNE00414.1 - 0.0025 16.9 0.0 0.0035 16.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1704) BAR_2 PF10455.9 KNE00416.1 - 4.7e-84 281.9 14.7 6e-84 281.6 14.7 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking PRP38 PF03371.15 KNE00417.1 - 5.9e-48 163.0 0.2 6.6e-48 162.9 0.2 1.0 1 0 0 1 1 1 1 PRP38 family Nup84_Nup100 PF04121.13 KNE00419.1 - 1.2e-157 526.1 12.7 1.4e-157 526.0 12.7 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Pept_S41_N PF18294.1 KNE00419.1 - 0.039 14.0 1.6 0.7 9.9 0.1 3.2 3 0 0 3 3 3 0 Peptidase S41 N-terminal domain DUF5638 PF18688.1 KNE00419.1 - 0.042 14.2 2.7 0.12 12.7 0.7 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5638) ROK PF00480.20 KNE00419.1 - 0.17 11.3 0.1 0.65 9.4 0.0 1.9 2 0 0 2 2 2 0 ROK family RPN6_N PF18055.1 KNE00420.1 - 1.4e-33 115.7 3.3 1.4e-33 115.7 3.3 3.0 3 1 1 4 4 4 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KNE00420.1 - 3.2e-17 63.0 0.2 3.2e-17 63.0 0.2 2.6 2 1 1 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 KNE00420.1 - 8e-11 41.5 0.8 1.8e-10 40.4 0.8 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_MalT PF17874.1 KNE00420.1 - 0.0048 16.3 0.6 0.0096 15.3 0.6 1.4 1 0 0 1 1 1 1 MalT-like TPR region TPR_12 PF13424.6 KNE00420.1 - 0.01 16.1 7.7 2.1 8.7 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat DDRGK PF09756.9 KNE00420.1 - 0.011 15.4 0.7 0.011 15.4 0.7 2.5 2 1 1 3 3 3 0 DDRGK domain TPR_20 PF14561.6 KNE00420.1 - 0.33 11.3 5.1 6.9 7.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KNE00420.1 - 0.38 11.4 2.7 63 4.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KNE00420.1 - 3.3 8.0 11.4 49 4.4 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Methyltransf_23 PF13489.6 KNE00421.1 - 6.5e-20 71.6 0.0 1.2e-19 70.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNE00421.1 - 1.9e-13 50.9 0.0 4.3e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KNE00421.1 - 9.3e-13 48.0 0.0 1.5e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KNE00421.1 - 2.2e-12 47.5 0.0 4.8e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNE00421.1 - 6.5e-11 42.7 0.0 1.1e-10 42.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNE00421.1 - 8.1e-10 38.7 0.0 2.6e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Glyco_tran_WecB PF03808.13 KNE00421.1 - 0.043 13.8 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Synaptobrevin PF00957.21 KNE00421.1 - 0.047 13.5 0.2 0.97 9.3 0.0 2.5 2 0 0 2 2 2 0 Synaptobrevin SlyX PF04102.12 KNE00422.1 - 0.0033 18.0 1.6 0.0033 18.0 1.6 1.9 1 1 1 2 2 2 1 SlyX Macscav_rec PF03523.13 KNE00422.1 - 0.0054 16.6 1.6 0.26 11.2 0.1 2.2 2 0 0 2 2 2 1 Macrophage scavenger receptor Casc1_N PF15927.5 KNE00422.1 - 0.0066 16.2 3.8 0.0077 16.0 3.8 1.2 1 0 0 1 1 1 1 Cancer susceptibility candidate 1 N-terminus DivIC PF04977.15 KNE00422.1 - 0.0068 16.2 2.0 0.0068 16.2 2.0 1.9 2 0 0 2 2 2 1 Septum formation initiator MCC-bdg_PDZ PF10506.9 KNE00422.1 - 0.034 14.2 2.3 0.15 12.1 0.6 2.3 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF489 PF04356.12 KNE00422.1 - 0.066 13.2 0.5 0.073 13.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF2594 PF10769.9 KNE00422.1 - 0.076 13.1 0.8 7.2 6.7 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2594) DUF1664 PF07889.12 KNE00422.1 - 0.1 12.6 1.8 0.13 12.3 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.21 KNE00422.1 - 0.29 11.3 4.1 0.67 10.1 3.4 2.0 1 1 1 2 2 2 0 bZIP transcription factor PCRF PF03462.18 KNE00423.1 - 2.8e-47 161.1 0.1 8e-47 159.6 0.0 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KNE00423.1 - 1.4e-35 121.7 2.2 2.8e-35 120.7 2.2 1.5 1 0 0 1 1 1 1 RF-1 domain RRM_1 PF00076.22 KNE00424.1 - 1.3e-09 37.7 0.0 1.9e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KNE00424.1 - 1.7e-07 30.9 0.1 1.9e-07 30.7 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KNE00424.1 - 0.013 15.6 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 RRM_occluded PF16842.5 KNE00424.1 - 0.023 14.5 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Amino_oxidase PF01593.24 KNE00425.1 - 1.3e-15 57.7 0.0 1.6e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KNE00425.1 - 4.4e-12 46.1 0.0 8.4e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KNE00425.1 - 1.7e-06 27.5 0.1 9.5e-06 25.0 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KNE00425.1 - 1.3e-05 25.7 0.0 0.013 16.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KNE00425.1 - 0.0005 19.8 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase CHDCT2 PF08074.11 KNE00425.1 - 0.0014 18.8 0.0 0.0028 17.9 0.0 1.4 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain NAD_binding_9 PF13454.6 KNE00425.1 - 0.0019 18.2 0.0 0.004 17.2 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Mqo PF06039.15 KNE00425.1 - 0.002 16.7 0.0 0.0062 15.1 0.0 1.8 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) PSDC PF12588.8 KNE00425.1 - 0.035 14.1 0.5 0.19 11.7 0.1 2.3 2 0 0 2 2 2 0 Phophatidylserine decarboxylase Pyr_redox_2 PF07992.14 KNE00425.1 - 0.051 12.8 0.0 0.25 10.6 0.0 2.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Arrestin_C PF02752.22 KNE00426.1 - 2.2e-09 37.9 0.2 7.5e-05 23.2 0.0 2.7 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain DAGK_cat PF00781.24 KNE00428.1 - 8.7e-24 83.5 0.0 1.4e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Thioredoxin PF00085.20 KNE00429.1 - 4.7e-15 55.4 0.0 6e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 KNE00429.1 - 3.3e-05 23.6 0.0 4e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KNE00429.1 - 0.00023 21.6 0.2 0.00045 20.6 0.2 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KNE00429.1 - 0.0033 17.7 0.0 0.18 12.1 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 KNE00429.1 - 0.081 12.6 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 Redoxin Thioredoxin_4 PF13462.6 KNE00429.1 - 0.096 12.8 0.5 2.9 8.0 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin Sugar_tr PF00083.24 KNE00431.1 - 6.5e-86 289.0 26.7 7.6e-86 288.7 26.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNE00431.1 - 5.9e-15 55.0 49.0 6.2e-13 48.4 20.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4293 PF14126.6 KNE00431.1 - 0.12 12.6 1.3 0.39 11.0 1.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) 2-Hacid_dh_C PF02826.19 KNE00432.1 - 6.5e-55 185.2 0.0 1.1e-54 184.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KNE00432.1 - 1.5e-37 128.2 0.1 2e-37 127.8 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KNE00432.1 - 4.9e-06 26.8 0.6 1.2e-05 25.5 0.3 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 KNE00432.1 - 2.3e-05 24.5 0.1 4.4e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.25 KNE00432.1 - 0.00011 21.8 0.0 0.00032 20.4 0.0 1.7 1 0 0 1 1 1 1 ACT domain IlvN PF07991.12 KNE00432.1 - 0.0016 18.0 0.3 0.0039 16.8 0.1 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 KNE00432.1 - 0.011 16.2 0.0 0.032 14.7 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain DpaA_N PF16924.5 KNE00432.1 - 0.016 15.3 0.1 1.4 9.0 0.0 2.9 2 1 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain 3HCDH_N PF02737.18 KNE00432.1 - 0.031 14.1 0.0 0.08 12.8 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain A_deaminase PF00962.22 KNE00433.1 - 2.5e-44 152.0 0.0 3.9e-44 151.3 0.0 1.2 1 1 0 1 1 1 1 Adenosine/AMP deaminase MFS_1 PF07690.16 KNE00434.1 - 6.3e-27 94.4 24.2 8.7e-27 94.0 24.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KNE00434.1 - 2.3e-09 37.1 0.4 2.3e-09 37.1 0.4 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF2650 PF10853.8 KNE00434.1 - 0.68 9.7 3.6 0.65 9.8 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2650) Kinesin PF00225.23 KNE00435.1 - 1.5e-99 333.1 0.0 1.5e-99 333.1 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KNE00435.1 - 3e-23 82.4 0.1 4.3e-22 78.7 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding Pox_A_type_inc PF04508.12 KNE00435.1 - 0.06 13.2 4.0 0.7 9.8 4.1 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat rve_3 PF13683.6 KNE00435.1 - 1.4 8.7 3.5 6.3 6.7 0.1 2.8 3 0 0 3 3 3 0 Integrase core domain EamA PF00892.20 KNE00437.1 - 0.00012 22.2 48.4 0.00019 21.6 6.8 3.3 3 2 0 3 3 3 2 EamA-like transporter family Ifi-6-16 PF06140.13 KNE00437.1 - 1.3 9.0 5.5 0.8 9.7 0.4 2.5 2 0 0 2 2 2 0 Interferon-induced 6-16 family PX PF00787.24 KNE00438.1 - 8.3e-20 70.9 0.2 2.2e-19 69.5 0.2 1.8 1 0 0 1 1 1 1 PX domain Peptidase_C10 PF01640.17 KNE00438.1 - 0.00077 19.8 1.4 0.37 11.1 0.2 2.6 2 0 0 2 2 2 2 Peptidase C10 family Mei5_like PF17021.5 KNE00438.1 - 0.012 15.7 2.1 0.97 9.5 0.0 3.5 3 0 0 3 3 3 0 Putative double-strand recombination repair-like FidL_like PF15941.5 KNE00438.1 - 0.27 11.7 4.3 0.64 10.5 0.1 3.4 3 0 0 3 3 3 0 FidL-like putative membrane protein DUF3445 PF11927.8 KNE00439.1 - 1.7e-68 230.6 0.0 2.3e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) SpoU_methylase PF00588.19 KNE00440.1 - 7.2e-26 91.1 0.0 2.6e-24 86.0 0.0 2.5 2 0 0 2 2 2 1 SpoU rRNA Methylase family DUF592 PF04574.13 KNE00440.1 - 0.062 13.1 0.0 0.5 10.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF592) RNase_PH PF01138.21 KNE00441.1 - 7.9e-08 32.9 0.1 5.2e-07 30.2 0.1 2.0 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KNE00441.1 - 0.00027 20.9 0.0 0.00087 19.3 0.0 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Nup35_RRM PF05172.13 KNE00442.1 - 7.1e-25 86.9 0.0 1.4e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 KNE00442.1 - 0.00026 20.9 0.1 0.0021 18.0 0.1 2.2 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF2418 PF10332.9 KNE00443.1 - 2.6e-24 85.6 2.5 5.5e-24 84.5 2.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) Wzy_C PF04932.15 KNE00443.1 - 0.057 13.1 0.1 9.4 5.9 0.0 2.3 2 0 0 2 2 2 0 O-Antigen ligase SlyX PF04102.12 KNE00444.1 - 0.0031 18.1 10.5 0.27 11.9 0.5 4.3 3 1 1 4 4 4 1 SlyX CASP_C PF08172.12 KNE00444.1 - 0.0051 16.2 7.4 0.0051 16.2 7.4 2.0 2 0 0 2 2 2 1 CASP C terminal Spc110_C PF18520.1 KNE00444.1 - 0.024 14.2 0.3 0.065 12.9 0.3 1.7 1 0 0 1 1 1 0 Spindle pole body component 110 C-terminal domain DUF1664 PF07889.12 KNE00444.1 - 0.092 12.8 2.5 2.5 8.1 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YabA PF06156.13 KNE00444.1 - 0.27 11.9 15.0 0.17 12.5 1.1 3.4 2 1 0 3 3 3 0 Initiation control protein YabA FlaC_arch PF05377.11 KNE00444.1 - 0.31 11.5 4.3 1.2 9.6 0.2 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) SHE3 PF17078.5 KNE00444.1 - 0.41 10.3 11.4 0.023 14.4 3.4 2.5 1 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 ADIP PF11559.8 KNE00444.1 - 4 7.5 24.0 0.57 10.3 3.1 3.4 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding XRN_M PF17846.1 KNE00444.1 - 4.4 6.1 9.6 0.07 12.1 1.7 1.7 2 0 0 2 2 2 0 Xrn1 helical domain Y_phosphatase PF00102.27 KNE00445.1 - 1.2e-56 191.9 0.6 1.7e-56 191.4 0.6 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 KNE00445.1 - 8.2e-07 29.5 0.0 8.8e-06 26.2 0.0 2.6 3 0 0 3 3 3 1 Rhodanese-like domain DSPc PF00782.20 KNE00445.1 - 0.051 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KNE00445.1 - 0.074 13.0 0.0 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family DUF3802 PF12290.8 KNE00445.1 - 0.13 12.7 0.0 0.74 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3802) Prenyltrans PF00432.21 KNE00448.1 - 1.1e-42 143.4 11.6 2.3e-10 40.0 0.1 5.2 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat DUF3575 PF12099.8 KNE00448.1 - 0.099 11.9 0.0 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3575) UBX PF00789.20 KNE00449.1 - 1.8e-08 34.4 0.0 4.2e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 UBX domain TSNAXIP1_N PF15739.5 KNE00449.1 - 0.026 14.9 7.4 0.048 14.0 7.4 1.4 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus SRP14 PF02290.15 KNE00451.1 - 1.3e-23 83.2 0.0 1.3e-23 83.2 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle 14kD protein MFS_1 PF07690.16 KNE00453.1 - 5.7e-25 88.0 19.9 1.1e-24 87.0 19.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KNE00453.1 - 4.1e-18 65.8 6.8 4.1e-18 65.8 6.8 2.6 2 1 1 3 3 3 1 Nodulin-like Sugar_tr PF00083.24 KNE00453.1 - 4e-06 26.0 22.3 0.00037 19.5 4.7 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TarH PF02203.15 KNE00453.1 - 0.48 10.3 2.7 4.9 7.0 0.1 2.8 2 1 1 3 3 3 0 Tar ligand binding domain homologue MFS_3 PF05977.13 KNE00453.1 - 0.53 8.6 6.9 0.98 7.7 0.5 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Dynamin_N PF00350.23 KNE00454.1 - 3.2e-16 59.8 0.0 1.1e-15 58.2 0.0 2.0 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KNE00454.1 - 6.7e-11 42.3 0.0 2.8e-10 40.3 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KNE00454.1 - 4.3e-06 26.4 0.2 0.0021 17.6 0.4 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Roc PF08477.13 KNE00454.1 - 0.013 15.7 0.0 4.2 7.6 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KNE00454.1 - 0.02 15.4 0.0 0.088 13.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KNE00454.1 - 0.039 13.9 1.9 13 5.7 0.2 3.6 2 1 1 3 3 3 0 RsgA GTPase DUF3883 PF13020.6 KNE00454.1 - 0.068 13.2 0.2 0.25 11.4 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3883) PglZ PF08665.12 KNE00454.1 - 1.2 9.2 6.2 0.71 10.0 0.1 3.4 4 0 0 4 4 4 0 PglZ domain Ureidogly_lyase PF04115.12 KNE00455.1 - 8.4e-59 198.5 0.0 1e-58 198.2 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase Adaptin_binding PF10199.9 KNE00456.1 - 2.3e-06 28.2 5.8 2.2e-05 25.0 4.3 2.5 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 DUF2951 PF11166.8 KNE00456.1 - 0.038 14.2 2.7 0.47 10.7 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) AAA_18 PF13238.6 KNE00456.1 - 0.11 13.0 0.2 0.56 10.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain Sec15 PF04091.12 KNE00457.1 - 4.9e-86 289.0 2.5 4.9e-86 289.0 2.5 1.7 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Protoglobin PF11563.8 KNE00457.1 - 0.053 13.4 1.2 2.2 8.2 0.1 3.0 3 0 0 3 3 3 0 Protoglobin DUF3920 PF13058.6 KNE00457.1 - 0.069 13.4 1.9 2.7 8.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3920) Sec8_exocyst PF04048.14 KNE00457.1 - 0.077 12.9 5.5 0.35 10.8 5.5 2.2 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain LOH1CR12 PF10158.9 KNE00457.1 - 0.085 12.9 4.6 0.11 12.5 2.6 2.2 2 0 0 2 2 2 0 Tumour suppressor protein AAA_lid_10 PF17872.1 KNE00457.1 - 0.14 12.3 1.4 0.58 10.3 1.4 2.0 1 1 0 1 1 1 0 AAA lid domain Rtt106 PF08512.12 KNE00457.1 - 0.2 12.1 1.5 0.54 10.7 0.4 2.3 2 0 0 2 2 2 0 Histone chaperone Rttp106-like DUF3929 PF13066.6 KNE00458.1 - 0.19 11.8 0.5 0.3 11.2 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3929) NuA4 PF09340.10 KNE00459.1 - 1.5e-26 92.1 2.3 2.1e-26 91.6 2.3 1.2 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 ZapB PF06005.12 KNE00459.1 - 0.043 14.3 3.9 0.064 13.7 3.9 1.2 1 0 0 1 1 1 0 Cell division protein ZapB MRP-L28 PF09812.9 KNE00460.1 - 1.7e-31 109.5 2.9 2e-31 109.3 2.9 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 TssO PF17561.2 KNE00460.1 - 0.072 13.2 1.1 0.092 12.8 0.7 1.4 1 1 0 1 1 1 0 Type VI secretion system, TssO Pkinase PF00069.25 KNE00462.1 - 2.4e-71 240.2 0.0 3.9e-71 239.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE00462.1 - 4e-32 111.5 0.0 5.7e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KNE00462.1 - 5.5e-11 43.0 1.0 1.4e-10 41.7 1.0 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KNE00462.1 - 1.9e-06 27.1 0.2 4.2e-06 25.9 0.2 1.5 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KNE00462.1 - 0.0024 17.5 0.1 2.2 7.9 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KNE00462.1 - 0.0025 17.2 0.0 0.0054 16.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KNE00462.1 - 0.0053 16.1 0.0 0.015 14.6 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KNE00463.1 - 3.2e-69 233.3 0.0 7.1e-69 232.1 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE00463.1 - 2.5e-36 125.3 0.0 4.8e-36 124.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 KNE00463.1 - 2e-13 50.0 0.4 7.2e-13 48.3 0.4 1.9 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Kinase-like PF14531.6 KNE00463.1 - 0.0059 16.0 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KNE00463.1 - 0.0077 15.6 0.2 0.037 13.4 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KNE00463.1 - 0.057 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family zinc_ribbon_16 PF17034.5 KNE00464.1 - 1.5e-25 89.8 10.6 1.5e-25 89.8 10.6 1.9 2 0 0 2 2 2 1 Zinc-ribbon like family WD40 PF00400.32 KNE00464.1 - 0.00031 21.5 3.6 0.71 10.9 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat zf-PHD-like PF15446.6 KNE00464.1 - 0.012 15.3 0.1 0.035 13.7 0.1 1.7 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Zn_ribbon_17 PF17120.5 KNE00464.1 - 0.019 14.6 7.5 0.061 13.0 7.5 1.9 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zinc_ribbon_2 PF13240.6 KNE00464.1 - 0.062 13.0 1.6 0.32 10.8 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KNE00464.1 - 0.095 12.1 2.7 0.54 9.7 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KNE00464.1 - 5.7 7.1 7.5 0.66 10.1 0.3 2.7 3 0 0 3 3 3 0 Zinc ribbon domain Pkinase PF00069.25 KNE00465.1 - 5e-61 206.4 0.0 9.3e-61 205.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE00465.1 - 1.6e-36 125.9 0.0 2.8e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 KNE00465.1 - 8.3e-20 70.7 18.2 6.7e-10 38.9 4.0 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 KNE00465.1 - 5.9e-18 64.5 40.6 4.3e-11 42.5 14.5 2.8 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KNE00465.1 - 9.7e-13 48.6 1.6 9.7e-13 48.6 1.6 2.3 2 0 0 2 2 1 1 Protein kinase C terminal domain C2 PF00168.30 KNE00465.1 - 9.1e-05 22.7 0.0 0.00018 21.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain Haspin_kinase PF12330.8 KNE00465.1 - 0.00018 20.6 1.5 0.0067 15.4 0.1 2.2 1 1 1 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 KNE00465.1 - 0.01 15.2 0.1 0.038 13.3 0.0 2.0 2 0 0 2 2 2 0 Kinase-like DUF2443 PF10398.9 KNE00465.1 - 0.098 12.7 0.0 0.4 10.7 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) C1_2 PF03107.16 KNE00465.1 - 0.64 10.4 27.9 1.1 9.6 12.4 2.7 2 0 0 2 2 2 0 C1 domain Uds1 PF15456.6 KNE00465.1 - 0.85 9.8 4.2 0.18 12.0 0.3 1.8 2 0 0 2 2 2 0 Up-regulated During Septation Ras PF00071.22 KNE00466.1 - 3.9e-21 75.3 0.0 6.1e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNE00466.1 - 1e-08 35.4 0.0 2.1e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KNE00466.1 - 0.00082 19.7 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_32 PF13654.6 KNE00466.1 - 0.0011 17.9 0.0 0.0016 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KNE00466.1 - 0.0021 18.5 0.0 0.0036 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KNE00466.1 - 0.0093 15.5 0.0 0.027 14.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KNE00466.1 - 0.0096 15.8 0.0 0.021 14.7 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 KNE00466.1 - 0.019 14.7 0.1 0.14 11.9 0.0 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 KNE00466.1 - 0.022 14.5 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 KNE00466.1 - 0.037 13.5 0.1 0.17 11.4 0.1 2.0 1 1 0 1 1 1 0 HPr Serine kinase C-terminal domain MMR_HSR1 PF01926.23 KNE00466.1 - 0.04 14.0 0.0 0.089 12.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 KNE00466.1 - 0.045 13.1 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Septin PF00735.18 KNE00466.1 - 0.058 12.7 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 Septin NACHT PF05729.12 KNE00466.1 - 0.09 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 KNE00466.1 - 0.098 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain UPF0767 PF15990.5 KNE00466.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 UPF0767 family ATPase PF06745.13 KNE00466.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 KaiC Myosin_head PF00063.21 KNE00466.1 - 0.13 10.4 0.0 0.19 9.9 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) DLIC PF05783.11 KNE00466.1 - 0.15 10.9 0.0 0.15 10.9 0.0 1.7 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_5 PF07728.14 KNE00466.1 - 0.18 11.8 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CBF PF03914.17 KNE00467.1 - 8.8e-46 156.0 0.2 8.8e-46 156.0 0.2 3.2 4 1 0 4 4 4 1 CBF/Mak21 family DUF1512 PF07431.12 KNE00467.1 - 0.036 13.1 0.3 0.082 11.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) NOC3p PF07540.11 KNE00467.1 - 0.12 12.8 0.9 0.75 10.3 0.4 2.8 2 0 0 2 2 2 0 Nucleolar complex-associated protein Pkinase PF00069.25 KNE00468.1 - 1.9e-61 207.7 0.0 2.7e-61 207.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE00468.1 - 5.2e-34 117.7 0.0 6.9e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNE00468.1 - 2.1e-06 27.3 0.2 1.1e-05 24.9 0.0 2.3 2 1 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 KNE00468.1 - 6.6e-06 25.2 0.0 1.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Hamartin PF04388.12 KNE00468.1 - 0.25 9.9 4.4 0.36 9.5 4.4 1.1 1 0 0 1 1 1 0 Hamartin protein DIT1_PvcA PF05141.12 KNE00469.1 - 2.1e-86 289.8 0.0 3.1e-86 289.3 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein HNH_4 PF13395.6 KNE00469.1 - 0.015 15.2 0.2 0.043 13.7 0.1 1.9 2 0 0 2 2 2 0 HNH endonuclease UPF0047 PF01894.17 KNE00470.1 - 5.5e-37 126.4 0.0 6.8e-37 126.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 PHD PF00628.29 KNE00471.1 - 1.5e-09 37.6 7.7 1.5e-09 37.6 7.7 2.0 2 0 0 2 2 2 1 PHD-finger PEPcase PF00311.17 KNE00471.1 - 0.046 11.8 1.8 0.06 11.4 1.8 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase V_ATPase_I PF01496.19 KNE00471.1 - 0.14 10.1 5.0 0.18 9.7 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S49_N PF08496.10 KNE00471.1 - 0.62 10.1 6.2 1.3 9.0 6.2 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal zf-HC5HC2H PF13771.6 KNE00471.1 - 0.71 10.2 9.5 0.18 12.0 4.4 2.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain DUF3835 PF12927.7 KNE00471.1 - 3.3 8.6 9.1 5.4 7.9 4.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) CAF1C_H4-bd PF12265.8 KNE00472.1 - 2.2e-14 53.4 0.1 9.2e-14 51.5 0.1 2.1 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KNE00472.1 - 7.8e-09 36.0 9.1 2.6 9.0 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNE00472.1 - 0.0012 19.1 0.1 0.38 11.1 0.0 3.4 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Vps55 PF04133.14 KNE00473.1 - 2.2e-32 111.5 4.3 2.6e-32 111.2 4.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF1206 PF06724.11 KNE00473.1 - 0.033 14.3 2.9 5.9 7.0 0.0 2.8 2 1 0 3 3 3 0 Domain of Unknown Function (DUF1206) DUF1077 PF06417.12 KNE00474.1 - 3e-43 146.6 3.4 3.7e-43 146.3 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) THUMP PF02926.17 KNE00475.1 - 2e-23 83.1 0.8 3.3e-23 82.4 0.8 1.4 1 0 0 1 1 1 1 THUMP domain F-box-like PF12937.7 KNE00476.1 - 8.6e-06 25.6 0.1 1.9e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KNE00476.1 - 2.3e-05 24.1 0.1 5.2e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 F-box domain COMMD1_N PF17221.3 KNE00476.1 - 0.0098 16.2 0.4 0.019 15.3 0.4 1.5 1 0 0 1 1 1 1 COMMD1 N-terminal domain HSP70 PF00012.20 KNE00477.1 - 2e-223 743.0 8.0 2.3e-223 742.7 8.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KNE00477.1 - 2e-16 59.7 9.2 2.3e-16 59.5 1.6 2.7 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 KNE00477.1 - 3.9e-05 23.5 0.0 8.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 KNE00477.1 - 0.0027 17.3 0.3 0.31 10.5 0.0 2.8 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 KNE00477.1 - 0.043 14.2 4.9 2 8.9 0.0 4.5 4 2 0 4 4 4 0 Cell division protein FtsA Proteasome PF00227.26 KNE00478.1 - 1.2e-47 161.8 0.0 1.6e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KNE00478.1 - 1e-10 41.0 0.1 1e-10 41.0 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Phage_CRI PF05144.14 KNE00478.1 - 0.045 13.1 0.1 0.072 12.4 0.1 1.2 1 0 0 1 1 1 0 Phage replication protein CRI DUF2406 PF10295.9 KNE00478.1 - 0.1 13.3 0.8 2 9.2 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein (DUF2406) Enolase_C PF00113.22 KNE00479.1 - 4.9e-154 511.9 0.1 8e-154 511.2 0.1 1.3 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KNE00479.1 - 3.4e-56 189.0 0.1 6e-56 188.2 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KNE00479.1 - 0.0002 21.0 0.0 0.00034 20.3 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like Aminotran_5 PF00266.19 KNE00480.1 - 7.8e-11 41.5 0.0 1.2e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KNE00480.1 - 0.18 11.1 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family CBP4 PF07960.11 KNE00482.1 - 2.7e-53 179.3 0.7 3.1e-53 179.1 0.7 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 KNE00482.1 - 0.075 13.0 0.3 0.14 12.1 0.0 1.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Fungal_trans_2 PF11951.8 KNE00483.1 - 2.1e-12 46.6 0.3 3.6e-12 45.8 0.4 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNE00483.1 - 4.9e-08 33.0 8.4 7.8e-08 32.3 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ras PF00071.22 KNE00484.1 - 2.1e-50 170.5 0.0 2.6e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNE00484.1 - 5.1e-18 65.4 0.0 7e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNE00484.1 - 1.9e-07 30.7 0.0 2.5e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family HMG_box_2 PF09011.10 KNE00485.1 - 3.2e-08 34.0 21.8 1.6e-05 25.4 2.8 4.6 3 2 0 3 3 3 2 HMG-box domain HMG_box PF00505.19 KNE00485.1 - 9.7e-07 29.1 17.2 0.0031 17.9 0.5 4.8 4 1 1 5 5 5 2 HMG (high mobility group) box Protamine_like PF06382.11 KNE00485.1 - 0.0037 17.4 6.1 0.26 11.5 0.1 2.6 1 1 1 2 2 2 2 Protamine and protamine like Med2 PF11214.8 KNE00485.1 - 0.055 13.6 6.0 0.14 12.3 6.0 1.7 1 0 0 1 1 1 0 Mediator complex subunit 2 DUF501 PF04417.12 KNE00485.1 - 0.12 12.1 1.1 0.25 11.1 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF501) THOC7 PF05615.13 KNE00485.1 - 9.5 6.5 15.3 2.6 8.3 7.1 2.7 1 1 0 2 2 2 0 Tho complex subunit 7 Say1_Mug180 PF10340.9 KNE00486.1 - 5e-23 81.6 0.0 1.3e-22 80.2 0.0 1.6 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 KNE00486.1 - 4.9e-12 46.2 0.0 8.1e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold TruD PF01142.18 KNE00486.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 tRNA pseudouridine synthase D (TruD) Cpn60_TCP1 PF00118.24 KNE00488.1 - 3.8e-152 507.4 12.7 4.3e-152 507.2 12.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cyclin_N PF00134.23 KNE00489.1 - 3.6e-14 52.6 0.0 5.9e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KNE00489.1 - 8.4e-09 36.0 0.4 2.7e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 Cyclin FAM199X PF15814.5 KNE00489.1 - 0.023 13.7 3.6 0.032 13.3 3.6 1.2 1 0 0 1 1 1 0 Protein family FAM199X Na_Ca_ex PF01699.24 KNE00491.1 - 1.4e-44 151.7 36.3 6.4e-23 81.4 8.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein YscJ_FliF PF01514.17 KNE00491.1 - 0.0075 15.9 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 Secretory protein of YscJ/FliF family 7tm_3 PF00003.22 KNE00491.1 - 0.0094 15.7 1.9 0.0094 15.7 1.9 3.5 2 1 1 3 3 3 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF2157 PF09925.9 KNE00491.1 - 3 7.6 13.1 0.44 10.3 3.9 3.3 2 2 0 2 2 2 0 Predicted membrane protein (DUF2157) SE PF08491.10 KNE00492.1 - 2.6e-118 394.1 0.0 3.2e-118 393.8 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KNE00492.1 - 7.3e-10 38.6 0.0 5.6e-09 35.7 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KNE00492.1 - 1.6e-07 31.3 0.1 2.8e-05 23.9 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KNE00492.1 - 0.00034 20.8 0.1 0.00095 19.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KNE00492.1 - 0.00069 19.1 0.3 0.014 14.8 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KNE00492.1 - 0.0012 18.0 0.6 0.0045 16.1 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.18 KNE00492.1 - 0.0029 17.5 0.1 0.0047 16.8 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KNE00492.1 - 0.0037 17.3 0.0 0.0066 16.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KNE00492.1 - 0.011 16.2 0.1 0.038 14.5 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KNE00492.1 - 0.017 14.3 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 KNE00492.1 - 0.036 14.3 0.0 0.062 13.6 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Thi4 PF01946.17 KNE00492.1 - 0.039 13.2 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KNE00492.1 - 0.047 12.8 0.1 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A ApbA PF02558.16 KNE00492.1 - 0.048 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 KNE00492.1 - 0.055 12.2 0.0 0.077 11.7 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 KNE00492.1 - 0.098 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KNE00492.1 - 0.19 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain W2 PF02020.18 KNE00493.1 - 5.1e-16 58.6 5.9 5.1e-16 58.6 5.9 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KNE00493.1 - 1.5e-09 37.2 19.4 0.0025 17.5 2.8 4.0 2 1 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KNE00493.1 - 1.4e-07 31.4 1.2 9e-07 28.7 0.0 2.6 3 1 0 3 3 3 1 Nucleotidyl transferase Hexapep_2 PF14602.6 KNE00493.1 - 0.00013 21.6 15.9 0.0011 18.7 2.8 3.7 1 1 2 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KNE00493.1 - 0.051 12.5 3.8 0.033 13.1 1.4 1.8 2 1 0 2 2 2 0 L-fucokinase NTP_transf_3 PF12804.7 KNE00493.1 - 0.062 13.7 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain DUF2118 PF09891.9 KNE00493.1 - 0.11 12.4 0.9 2.8 7.9 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2118) MFS_2 PF13347.6 KNE00494.1 - 0.11 11.0 0.6 1.9 6.9 0.1 2.0 2 0 0 2 2 2 0 MFS/sugar transport protein Ctr PF04145.15 KNE00495.1 - 7.9e-17 62.2 19.7 5.6e-15 56.2 19.7 2.0 1 1 0 1 1 1 1 Ctr copper transporter family 60KD_IMP PF02096.20 KNE00495.1 - 0.06 13.2 2.1 0.087 12.7 2.1 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein U3_assoc_6 PF08640.11 KNE00496.1 - 1.2e-28 99.0 4.8 1.1e-27 95.9 0.4 2.7 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KNE00496.1 - 1.3e-05 25.6 0.3 0.00052 20.6 0.3 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KNE00496.1 - 0.0063 16.8 0.6 1.2 9.6 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KNE00496.1 - 0.016 15.3 1.0 0.039 14.1 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat HAT PF02184.16 KNE00496.1 - 0.02 14.8 0.1 3.5 7.7 0.0 3.5 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat TPR_11 PF13414.6 KNE00496.1 - 0.021 14.5 0.2 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.6 KNE00496.1 - 0.029 15.0 1.4 0.22 12.2 0.7 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Saw1 PF11561.8 KNE00496.1 - 0.062 12.8 2.6 0.06 12.9 0.3 2.0 2 0 0 2 2 2 0 Single strand annealing-weakened 1 TPR_1 PF00515.28 KNE00496.1 - 0.089 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat NRDE-2 PF08424.10 KNE00496.1 - 0.17 11.0 3.1 3.9 6.5 0.1 3.2 2 1 2 4 4 4 0 NRDE-2, necessary for RNA interference FNIP PF05725.12 KNE00497.1 - 0.085 13.0 0.5 0.25 11.6 0.5 1.8 1 0 0 1 1 1 0 FNIP Repeat SWIRM PF04433.17 KNE00498.1 - 5.9e-14 52.2 3.1 1.2e-13 51.2 0.1 2.7 2 1 0 2 2 2 1 SWIRM domain ZZ PF00569.17 KNE00498.1 - 3.7e-13 49.1 7.7 6.6e-13 48.2 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 KNE00498.1 - 2.4e-10 40.4 0.1 6.6e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KNE00498.1 - 1e-06 28.8 0.2 4.5e-06 26.8 0.0 2.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain Baculo_IE-1 PF05290.11 KNE00498.1 - 0.56 10.2 4.0 1.5 8.8 4.0 1.7 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Ribosomal_S17e PF00833.18 KNE00499.1 - 1e-20 73.8 0.0 1.2e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal S17 Exotox-A_cataly PF09009.10 KNE00499.1 - 0.071 12.9 0.0 0.075 12.8 0.0 1.1 1 0 0 1 1 1 0 Exotoxin A catalytic DAO PF01266.24 KNE00500.1 - 1.5e-67 228.7 0.0 1.8e-67 228.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KNE00500.1 - 2.7e-05 24.3 0.1 5.7e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 KNE00500.1 - 0.00048 19.1 0.1 0.0007 18.5 0.1 1.2 1 0 0 1 1 1 1 MCRA family Pyr_redox_2 PF07992.14 KNE00500.1 - 0.0041 16.4 0.0 0.24 10.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KNE00500.1 - 0.0058 15.9 0.2 0.0097 15.2 0.2 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KNE00500.1 - 0.013 15.5 0.1 0.069 13.1 0.1 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 KNE00500.1 - 0.031 14.5 0.1 0.081 13.2 0.1 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Peptidase_M18 PF02127.15 KNE00503.1 - 7.5e-163 542.3 0.0 8.6e-163 542.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KNE00503.1 - 1.5e-05 24.2 0.0 0.035 13.1 0.0 2.7 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase HLH PF00010.26 KNE00504.1 - 2.7e-12 46.4 4.7 3.6e-12 46.0 0.5 2.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain BPL_N PF09825.9 KNE00504.1 - 0.13 11.3 1.5 0.19 10.8 1.5 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Nrap_D6 PF17407.2 KNE00504.1 - 0.9 9.8 4.1 1.8 8.8 0.1 3.1 2 1 2 4 4 4 0 Nrap protein domain 6 RIO1 PF01163.22 KNE00506.1 - 1.2e-71 240.3 2.4 1.2e-71 240.3 2.4 2.1 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KNE00506.1 - 0.00083 19.3 0.1 1 9.2 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family YL1 PF05764.13 KNE00506.1 - 0.27 11.3 35.4 0.064 13.4 30.6 2.0 2 0 0 2 2 2 0 YL1 nuclear protein CDC45 PF02724.14 KNE00506.1 - 0.65 8.2 24.1 0.99 7.6 24.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.16 KNE00506.1 - 0.73 9.9 3.1 1.1 9.2 3.1 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.7 KNE00506.1 - 3.6 5.6 11.3 4.9 5.2 11.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.12 KNE00506.1 - 9.1 6.0 19.9 8 6.2 18.3 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Kei1 PF08552.11 KNE00507.1 - 4e-09 36.6 0.1 4.7e-09 36.4 0.1 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 TLD PF07534.16 KNE00508.1 - 1.5e-25 90.1 0.8 3.1e-23 82.5 0.8 2.3 1 1 0 1 1 1 1 TLD AfaD PF05775.12 KNE00508.1 - 0.02 15.3 0.0 0.056 13.9 0.0 1.8 1 0 0 1 1 1 0 Enterobacteria AfaD invasin protein NUC153 PF08159.12 KNE00509.1 - 2.7e-13 49.5 1.4 2.7e-13 49.5 1.4 3.1 3 0 0 3 3 3 1 NUC153 domain Y_phosphatase3 PF13350.6 KNE00510.1 - 1.7e-37 129.6 0.0 2.6e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Hydrolase_4 PF12146.8 KNE00510.1 - 6.3e-07 28.9 0.1 0.00014 21.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Y_phosphatase2 PF03162.13 KNE00510.1 - 0.00012 21.8 0.0 0.0003 20.4 0.0 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family Abhydrolase_6 PF12697.7 KNE00510.1 - 0.00082 20.0 1.1 0.0028 18.3 1.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KNE00510.1 - 0.0019 17.9 0.4 0.084 12.5 0.1 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold CRPV_capsid PF08762.10 KNE00511.1 - 0.19 11.3 0.1 0.19 11.3 0.1 1.0 1 0 0 1 1 1 0 CRPV capsid protein like EMP24_GP25L PF01105.24 KNE00512.1 - 2.7e-54 183.9 0.6 3.1e-54 183.7 0.6 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ThiF PF00899.21 KNE00513.1 - 4.5e-60 203.0 0.0 5.9e-60 202.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KNE00513.1 - 1.8e-17 63.8 0.0 8.3e-17 61.7 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 KNE00513.1 - 0.0012 18.9 0.0 0.0039 17.3 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Herpes_BLRF2 PF05812.12 KNE00513.1 - 0.047 13.8 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Phage_holin_3_1 PF05106.12 KNE00513.1 - 0.049 14.1 0.0 0.094 13.2 0.0 1.5 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) JAKMIP_CC3 PF16034.5 KNE00513.1 - 0.054 13.4 1.2 0.086 12.8 1.2 1.3 1 0 0 1 1 1 0 JAKMIP CC3 domain UDPG_MGDP_dh_N PF03721.14 KNE00513.1 - 0.18 11.4 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TSC22 PF01166.18 KNE00513.1 - 0.19 12.1 0.7 0.48 10.8 0.7 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Wtap PF17098.5 KNE00513.1 - 0.36 10.8 3.3 0.35 10.8 1.3 1.8 2 0 0 2 2 2 0 WTAP/Mum2p family Cep57_CLD_2 PF14197.6 KNE00513.1 - 0.71 10.0 6.3 0.13 12.3 2.5 1.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Rad60-SLD PF11976.8 KNE00515.1 - 1.6e-17 63.1 0.4 4e-17 61.8 0.4 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Got1 PF04178.12 KNE00516.1 - 1.3e-33 115.8 20.8 1.9e-33 115.3 20.8 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family HIT PF01230.23 KNE00517.1 - 3.2e-24 85.5 0.1 4.1e-24 85.2 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KNE00517.1 - 7.1e-12 45.8 0.1 1.4e-11 44.9 0.0 1.4 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KNE00517.1 - 0.0031 17.4 1.2 0.0061 16.4 1.2 1.7 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 MBOAT PF03062.19 KNE00519.1 - 2e-57 195.1 16.3 2e-57 195.1 16.3 1.7 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family DnaJ_C PF01556.18 KNE00520.1 - 6.5e-40 136.6 0.1 8.4e-40 136.3 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KNE00520.1 - 1e-22 80.0 0.5 1.7e-22 79.3 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain RsgI_N PF12791.7 KNE00520.1 - 0.0064 16.4 0.2 0.015 15.2 0.2 1.5 1 0 0 1 1 1 1 Anti-sigma factor N-terminus SET PF00856.28 KNE00522.1 - 0.0012 19.3 0.0 0.018 15.5 0.0 2.3 2 1 0 2 2 2 1 SET domain DUF4590 PF15257.6 KNE00522.1 - 0.018 14.9 0.4 0.11 12.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4590) RFX_DNA_binding PF02257.15 KNE00524.1 - 1.8e-31 108.6 0.0 3.3e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 KNE00524.1 - 0.0039 17.7 0.0 0.032 14.7 0.0 2.5 2 1 1 3 3 3 1 Poxvirus D5 protein-like Ribosomal_L30 PF00327.20 KNE00527.1 - 9.5e-10 38.2 0.2 2.2e-09 37.0 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Dcc1 PF09724.9 KNE00528.1 - 1.4e-53 182.3 1.3 1.7e-53 182.1 1.3 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 XLF PF09302.11 KNE00528.1 - 0.024 14.8 3.5 2.3 8.4 0.1 2.5 3 0 0 3 3 3 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Mito_carr PF00153.27 KNE00529.1 - 2.3e-29 101.2 0.5 2.1e-16 59.6 0.1 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein Aminotran_5 PF00266.19 KNE00532.1 - 2.5e-91 306.4 0.0 2.9e-91 306.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KNE00532.1 - 1.7e-08 34.1 0.0 2.1e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 KNE00532.1 - 2e-05 23.5 0.0 3.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 KNE00532.1 - 0.00014 21.3 0.0 0.00027 20.4 0.0 1.4 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3369 PF11849.8 KNE00532.1 - 0.042 14.0 0.1 0.092 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3369) Iso_dh PF00180.20 KNE00533.1 - 2.8e-127 424.6 0.0 3.2e-127 424.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF3507 PF12015.8 KNE00534.1 - 3.6e-50 170.2 0.1 7.5e-50 169.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) RhoGEF PF00621.20 KNE00534.1 - 2.2e-06 28.0 5.2 2.3e-06 28.0 1.4 2.3 2 0 0 2 2 2 1 RhoGEF domain Peptidase_C15 PF01470.17 KNE00534.1 - 0.13 12.4 0.1 6.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Pyroglutamyl peptidase DUF2015 PF09435.10 KNE00535.1 - 1.1e-33 115.4 0.1 1.4e-33 115.1 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) WBP-1 PF11669.8 KNE00535.1 - 0.0043 17.7 0.2 0.0065 17.1 0.2 1.3 1 0 0 1 1 1 1 WW domain-binding protein 1 Ly49 PF08391.10 KNE00535.1 - 0.066 13.6 0.0 0.08 13.3 0.0 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region BatD PF13584.6 KNE00535.1 - 0.38 9.5 0.7 0.46 9.2 0.7 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF2897 PF11446.8 KNE00535.1 - 6.9 6.6 5.1 14 5.6 5.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) RRM_1 PF00076.22 KNE00536.1 - 1.6e-57 191.2 0.2 1.3e-21 76.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KNE00536.1 - 8.2e-06 25.8 0.9 0.4 10.8 0.0 3.7 3 2 0 3 3 3 3 Limkain b1 RRM_Rrp7 PF17799.1 KNE00536.1 - 2.3e-05 24.2 0.0 0.64 9.8 0.0 3.2 3 0 0 3 3 3 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 KNE00536.1 - 0.00014 21.9 0.1 3.4 7.8 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif RRM_occluded PF16842.5 KNE00536.1 - 0.0025 17.6 0.0 7 6.6 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif DUF1325 PF07039.11 KNE00537.1 - 1.2e-36 125.7 0.0 1.8e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 KNE00537.1 - 0.00045 20.0 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 KNE00537.1 - 0.0027 17.7 0.0 0.0065 16.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Spc7 PF08317.11 KNE00537.1 - 0.013 14.4 1.4 0.017 14.0 1.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Ntox11 PF15521.6 KNE00537.1 - 0.023 14.3 0.0 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 Novel toxin 11 Agenet PF05641.12 KNE00537.1 - 0.03 14.8 0.1 4.7 7.8 0.0 2.5 2 0 0 2 2 2 0 Agenet domain Trep_Strep PF09605.10 KNE00538.1 - 2.3 8.2 7.8 0.16 11.9 1.2 2.3 2 1 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) YchF-GTPase_C PF06071.13 KNE00539.1 - 2.6e-31 107.6 0.1 6.2e-31 106.4 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KNE00539.1 - 1.6e-15 57.2 0.0 4.7e-15 55.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 KNE00539.1 - 2.8e-06 27.3 0.0 1.1e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 TGS domain FeoB_N PF02421.18 KNE00539.1 - 0.0021 17.6 0.0 0.007 15.9 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B DASH_Duo1 PF08651.10 KNE00539.1 - 0.054 13.3 0.1 0.39 10.5 0.1 2.4 2 1 1 3 3 3 0 DASH complex subunit Duo1 Plasmid_RAQPRD PF09686.10 KNE00539.1 - 0.093 13.0 0.1 0.34 11.1 0.1 1.9 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) PLDc_2 PF13091.6 KNE00541.1 - 1e-17 64.3 0.0 4.4e-08 33.1 0.0 2.6 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.22 KNE00541.1 - 3.8e-07 30.0 0.3 0.018 15.2 0.1 3.0 2 1 0 2 2 2 2 Phospholipase D Active site motif DUF3533 PF12051.8 KNE00543.1 - 2.4e-129 431.6 19.1 3.1e-129 431.2 19.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF3810 PF12725.7 KNE00543.1 - 0.0031 16.9 0.1 0.0031 16.9 0.1 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3810) PDR_CDR PF06422.12 KNE00543.1 - 0.58 10.1 0.0 0.58 10.1 0.0 3.1 3 1 2 5 5 5 0 CDR ABC transporter Ribosomal_L27_C PF18471.1 KNE00545.1 - 3.8e-40 137.8 11.0 4.6e-40 137.6 11.0 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein C-terminal domain Ribosomal_L27 PF01016.19 KNE00545.1 - 3.2e-31 107.2 0.0 6.3e-31 106.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein DUF1104 PF06518.11 KNE00545.1 - 8.7 6.8 14.4 0.47 10.8 1.1 3.5 2 2 2 4 4 4 0 Protein of unknown function (DUF1104) Peptidase_M20 PF01546.28 KNE00546.1 - 5.6e-31 107.9 0.0 2.5e-30 105.8 0.0 1.9 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KNE00546.1 - 1e-11 44.7 0.0 2.1e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KNE00546.1 - 0.0014 18.4 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 RNA_pol_N PF01194.17 KNE00547.1 - 2.5e-30 104.6 0.8 2.8e-30 104.4 0.8 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 KNE00547.1 - 0.0065 16.7 0.3 0.008 16.4 0.3 1.2 1 0 0 1 1 1 1 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) WD40 PF00400.32 KNE00548.1 - 8.1e-05 23.3 0.3 0.044 14.7 0.0 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat Dynamin_N PF00350.23 KNE00549.1 - 8.7e-42 143.0 0.0 3.7e-41 141.0 0.0 2.2 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KNE00549.1 - 6.2e-06 26.3 0.0 2.4e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_M PF01031.20 KNE00549.1 - 0.012 14.8 13.2 0.025 13.8 3.5 3.5 3 2 0 3 3 3 0 Dynamin central region Zeta_toxin PF06414.12 KNE00549.1 - 0.013 14.8 0.9 4.9 6.4 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin DAGK_prokar PF01219.19 KNE00549.1 - 0.029 14.2 0.1 0.058 13.2 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic diacylglycerol kinase BCIP PF13862.6 KNE00549.1 - 0.036 13.8 2.8 0.047 13.5 0.2 2.3 2 0 0 2 2 2 0 p21-C-terminal region-binding protein AAA_21 PF13304.6 KNE00549.1 - 0.037 13.8 0.2 0.091 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KNE00549.1 - 0.042 14.2 0.3 0.25 11.7 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain DUF1140 PF06600.11 KNE00549.1 - 0.045 14.2 4.2 1.6 9.2 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1140) AAA_15 PF13175.6 KNE00549.1 - 0.047 13.4 0.0 0.047 13.4 0.0 3.7 2 1 0 2 2 1 0 AAA ATPase domain Serglycin PF04360.12 KNE00549.1 - 0.47 10.4 3.0 21 5.0 3.3 2.5 2 0 0 2 2 2 0 Serglycin AAA_23 PF13476.6 KNE00549.1 - 2.7 8.4 0.0 2.7 8.4 0.0 3.9 2 1 0 2 2 1 0 AAA domain Lectin_N PF03954.14 KNE00550.1 - 0.026 14.3 0.7 0.034 13.9 0.7 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain LapA_dom PF06305.11 KNE00550.1 - 0.043 13.6 1.1 0.059 13.2 1.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain BUD22 PF09073.10 KNE00555.1 - 0.94 8.7 9.6 1.2 8.3 9.6 1.2 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 KNE00555.1 - 2.7 7.2 7.6 4.1 6.6 7.6 1.3 1 0 0 1 1 1 0 NOA36 protein Ribosomal_60s PF00428.19 KNE00557.1 - 1.2e-24 86.7 13.4 1.5e-24 86.4 13.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Rhomboid PF01694.22 KNE00558.1 - 2.4e-26 92.5 15.3 3.8e-26 91.9 15.3 1.3 1 0 0 1 1 1 1 Rhomboid family Sec23_trunk PF04811.15 KNE00560.1 - 1.2e-27 97.0 0.1 2e-18 66.9 0.0 2.5 1 1 1 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KNE00560.1 - 3.3e-17 62.2 0.0 7.3e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KNE00560.1 - 3.5e-05 23.7 1.3 6.8e-05 22.8 1.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 KNE00560.1 - 0.00015 22.4 0.1 0.031 15.0 0.1 3.4 3 1 0 3 3 3 1 Sec23/Sec24 beta-sandwich domain A2L_zn_ribbon PF08792.10 KNE00560.1 - 0.029 14.1 0.8 0.1 12.4 0.8 1.9 1 0 0 1 1 1 0 A2L zinc ribbon domain CBF PF03914.17 KNE00560.1 - 0.076 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 CBF/Mak21 family Med2 PF11214.8 KNE00560.1 - 0.42 10.8 2.6 4.1 7.6 0.0 3.6 4 0 0 4 4 4 0 Mediator complex subunit 2 zf-ribbon_3 PF13248.6 KNE00560.1 - 2.5 7.6 6.2 9.8 5.7 0.2 2.8 3 0 0 3 3 3 0 zinc-ribbon domain DUF1749 PF08538.10 KNE00561.1 - 1.4e-81 273.8 0.0 1.6e-81 273.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KNE00561.1 - 3.2e-06 27.9 0.0 3.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNE00561.1 - 3.8e-06 26.4 0.0 4.1e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KNE00561.1 - 0.003 17.2 0.0 0.0057 16.3 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF900 PF05990.12 KNE00561.1 - 0.0031 17.0 0.0 0.0048 16.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DLH PF01738.18 KNE00561.1 - 0.0088 15.6 0.1 0.42 10.1 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family LIDHydrolase PF10230.9 KNE00561.1 - 0.017 14.7 0.0 0.046 13.3 0.0 1.6 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 KNE00561.1 - 0.023 14.3 0.0 1.4 8.5 0.0 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 KNE00561.1 - 0.026 14.2 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein LCAT PF02450.15 KNE00561.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase CASP_C PF08172.12 KNE00562.1 - 1.7e-66 224.2 10.1 1.7e-66 224.2 10.1 4.2 3 1 1 4 4 4 1 CASP C terminal YabA PF06156.13 KNE00562.1 - 0.01 16.5 4.4 0.01 16.5 4.4 7.4 4 1 2 6 6 6 0 Initiation control protein YabA Sec34 PF04136.15 KNE00562.1 - 0.019 14.8 2.3 0.019 14.8 2.3 5.6 5 1 0 5 5 5 0 Sec34-like family DUF2935 PF11155.8 KNE00562.1 - 0.42 11.0 19.4 6 7.2 0.9 4.9 3 1 0 4 4 4 0 Domain of unknown function (DUF2935) ubiquitin PF00240.23 KNE00562.1 - 0.44 10.3 10.6 0.71 9.7 0.9 3.9 3 0 0 3 3 3 0 Ubiquitin family HTH_40 PF14493.6 KNE00562.1 - 3.5 8.2 8.5 1.7 9.2 0.1 4.0 4 0 0 4 4 4 0 Helix-turn-helix domain UPF0242 PF06785.11 KNE00562.1 - 6 6.9 75.4 0.93 9.6 6.0 5.6 4 1 1 5 5 5 0 Uncharacterised protein family (UPF0242) N-terminus LPP PF04728.13 KNE00562.1 - 8.9 6.8 27.2 5.8 7.4 2.6 6.6 4 1 3 7 7 7 0 Lipoprotein leucine-zipper S4 PF01479.25 KNE00563.1 - 2.2e-11 43.3 1.2 4.4e-11 42.3 0.3 1.8 2 0 0 2 2 2 1 S4 domain Diphthami_syn_2 PF01902.17 KNE00565.1 - 1.4e-39 135.9 0.0 6.6e-39 133.7 0.0 2.1 2 1 0 2 2 2 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 KNE00565.1 - 1.3e-20 73.7 0.2 1.8e-11 44.1 0.0 2.3 2 0 0 2 2 2 2 Endoribonuclease L-PSP PPR_2 PF13041.6 KNE00566.1 - 1.2e-11 44.6 1.5 0.0072 16.5 0.0 5.7 2 1 4 6 6 6 3 PPR repeat family PPR PF01535.20 KNE00566.1 - 1.1e-10 41.1 0.1 0.019 15.2 0.0 4.8 4 0 0 4 4 4 3 PPR repeat PPR_long PF17177.4 KNE00566.1 - 8.5e-09 35.1 2.6 8e-05 22.1 0.0 2.9 2 1 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 KNE00566.1 - 0.00027 20.9 3.4 0.004 17.2 0.1 3.7 5 0 0 5 5 5 1 Pentatricopeptide repeat domain ERAP1_C PF11838.8 KNE00566.1 - 0.0021 17.7 0.1 0.016 14.7 0.0 2.4 3 0 0 3 3 3 1 ERAP1-like C-terminal domain DUF2767 PF10965.8 KNE00566.1 - 0.13 12.3 1.5 2.1 8.4 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2767) tRNA-synt_1 PF00133.22 KNE00567.1 - 1e-49 169.4 0.0 1.9e-29 102.4 0.2 6.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 KNE00567.1 - 7.2e-44 149.5 0.0 1.4e-43 148.6 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KNE00567.1 - 7.9e-28 97.3 0.8 1.1e-19 70.5 0.0 4.4 4 1 1 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KNE00567.1 - 6.2e-11 42.5 0.0 1.5e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KNE00567.1 - 0.0002 20.8 0.0 0.27 10.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain RIC1 PF07064.13 KNE00568.1 - 0.0064 15.9 0.2 0.011 15.1 0.2 1.4 1 0 0 1 1 1 1 RIC1 TPT PF03151.16 KNE00568.1 - 0.04 13.3 0.1 0.069 12.5 0.1 1.3 1 0 0 1 1 1 0 Triose-phosphate Transporter family WD40 PF00400.32 KNE00569.1 - 4.8e-07 30.4 2.4 9.5e-05 23.1 0.2 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNE00569.1 - 1.5e-06 28.4 0.0 0.0025 18.1 0.0 3.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 KNE00569.1 - 0.017 14.4 0.0 1.4 8.1 0.0 2.3 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller Taxilin PF09728.9 KNE00570.1 - 0.1 11.7 40.4 0.034 13.3 32.4 2.4 1 1 1 2 2 2 0 Myosin-like coiled-coil protein Herpes_UL17 PF04559.12 KNE00570.1 - 0.36 9.6 6.9 0.54 9.0 4.7 2.1 2 0 0 2 2 2 0 Herpesvirus UL17 protein KELK PF15796.5 KNE00570.1 - 0.73 10.3 44.0 0.46 11.0 10.9 4.9 2 1 1 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Mut7-C PF01927.16 KNE00570.1 - 3.1 7.9 10.6 0.37 10.9 2.8 2.9 1 1 0 2 2 2 0 Mut7-C RNAse domain Nup54 PF13874.6 KNE00572.1 - 0.00015 21.9 3.1 0.00029 20.9 3.1 1.5 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Say1_Mug180 PF10340.9 KNE00573.1 - 4.7e-56 190.2 1.1 5.6e-56 190.0 1.1 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 KNE00573.1 - 3.8e-18 66.1 0.0 5.4e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KNE00573.1 - 0.033 13.7 0.0 0.1 12.0 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2974 PF11187.8 KNE00573.1 - 0.048 13.2 0.0 8.9 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) SF1-HH PF16275.5 KNE00574.1 - 4.9e-36 123.5 0.1 1.4e-35 122.0 0.1 1.8 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 KNE00574.1 - 1.7e-06 27.8 0.0 8.5e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 KH domain zf-CCHC PF00098.23 KNE00574.1 - 5.9e-06 26.1 0.6 9.6e-06 25.4 0.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KNE00574.1 - 0.06 13.2 2.8 0.11 12.3 2.8 1.4 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.8 KNE00574.1 - 0.18 12.2 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G MTS PF05175.14 KNE00575.1 - 3.1e-09 36.6 0.0 1.5e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KNE00575.1 - 0.00035 21.3 0.0 0.024 15.4 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNE00575.1 - 0.0057 17.3 0.0 0.014 16.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 KNE00575.1 - 0.0079 15.9 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase DUF938 PF06080.12 KNE00575.1 - 0.056 13.2 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.19 KNE00575.1 - 0.08 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KNE00575.1 - 0.091 12.6 0.0 1.9 8.3 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KNE00575.1 - 0.15 11.9 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 KNE00575.1 - 0.17 11.6 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein RNA_pol_Rpb2_6 PF00562.28 KNE00576.1 - 8.9e-113 377.3 0.0 2e-112 376.1 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KNE00576.1 - 8.2e-39 133.2 0.0 1.2e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KNE00576.1 - 2.8e-28 97.9 0.0 6.7e-28 96.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 KNE00576.1 - 5.8e-28 97.8 0.0 1.1e-27 96.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 KNE00576.1 - 5.6e-24 83.9 0.0 1.3e-23 82.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 KNE00576.1 - 1.6e-16 60.5 0.1 5e-15 55.7 0.0 2.7 2 1 0 2 2 2 1 RNA polymerase Rpb2, domain 7 FUSC_2 PF13515.6 KNE00577.1 - 1e-33 116.1 5.8 1e-33 116.1 5.8 2.7 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KNE00577.1 - 2.5e-09 37.3 2.4 1.7e-08 34.6 0.1 2.4 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC PF04632.12 KNE00577.1 - 1.8e-05 23.5 1.4 0.023 13.2 0.0 3.0 3 0 0 3 3 3 2 Fusaric acid resistance protein family ALMT PF11744.8 KNE00577.1 - 0.003 16.5 7.9 0.003 16.5 7.9 2.6 2 2 0 2 2 2 1 Aluminium activated malate transporter LAGLIDADG_WhiA PF14527.6 KNE00577.1 - 0.071 13.2 0.2 0.38 10.9 0.1 2.2 2 0 0 2 2 2 0 WhiA LAGLIDADG-like domain Peptidase_S49_N PF08496.10 KNE00579.1 - 0.87 9.6 6.5 0.93 9.5 6.5 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ETRAMP PF09716.10 KNE00579.1 - 1.5 8.9 9.4 1.8 8.7 9.4 1.1 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) OB_NTP_bind PF07717.16 KNE00580.1 - 5.3e-24 84.4 0.0 2.9e-23 82.0 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KNE00580.1 - 5.2e-19 68.5 0.0 1.2e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KNE00580.1 - 2.1e-12 47.3 0.0 5.6e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KNE00580.1 - 2e-05 24.5 0.1 4.4e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.22 KNE00580.1 - 0.00013 21.6 0.1 0.00034 20.3 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KNE00580.1 - 0.00022 21.5 0.2 0.00078 19.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KNE00580.1 - 0.025 14.3 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KNE00580.1 - 0.047 12.8 0.0 0.091 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Flavi_DEAD PF07652.14 KNE00580.1 - 0.16 11.9 0.1 0.31 11.0 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain Arf PF00025.21 KNE00581.1 - 9e-66 220.6 0.1 1e-65 220.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KNE00581.1 - 2e-16 60.3 0.0 2.6e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KNE00581.1 - 1.9e-13 50.3 0.0 2.1e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KNE00581.1 - 1.1e-12 47.8 2.0 2.5e-09 36.7 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KNE00581.1 - 9.9e-11 41.4 0.0 1.2e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KNE00581.1 - 4.3e-10 39.3 0.0 5.2e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KNE00581.1 - 3.4e-06 27.1 0.0 4.6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.14 KNE00581.1 - 0.018 14.9 0.1 0.03 14.2 0.1 1.4 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.18 KNE00581.1 - 0.032 13.8 0.6 0.35 10.4 0.6 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Rib_5-P_isom_A PF06026.14 KNE00582.1 - 3e-59 199.5 0.0 3.6e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 KNE00582.1 - 0.067 13.1 0.0 4.6 7.2 0.0 2.3 1 1 1 2 2 2 0 DeoR C terminal sensor domain DUF3240 PF11582.8 KNE00583.1 - 0.057 13.6 0.0 0.061 13.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) Ribosomal_S7e PF01251.18 KNE00584.1 - 8.5e-79 263.6 0.5 9.5e-79 263.4 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e SH3_1 PF00018.28 KNE00585.1 - 1.1e-24 85.8 0.5 1.5e-12 46.9 0.1 2.5 2 0 0 2 2 2 2 SH3 domain FCH PF00611.23 KNE00585.1 - 2.7e-20 72.4 0.3 2.7e-20 72.4 0.3 2.9 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 KNE00585.1 - 8.6e-20 70.3 3.9 1.5e-10 40.7 0.1 3.2 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 KNE00585.1 - 2.2e-12 46.5 0.0 3.9e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_10 PF17902.1 KNE00585.1 - 0.024 14.7 0.0 6.6 6.9 0.0 3.0 3 0 0 3 3 3 0 SH3 domain Spectrin_like PF18373.1 KNE00585.1 - 0.026 14.6 0.5 0.084 12.9 0.1 2.1 2 0 0 2 2 2 0 Spectrin like domain Elongin_A PF06881.11 KNE00585.1 - 2.7 8.5 9.3 2 9.0 2.3 3.5 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF2183 PF09949.9 KNE00588.1 - 2.1e-34 117.8 0.1 4.9e-34 116.6 0.1 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Spermine_synt_N PF17284.2 KNE00588.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Spermidine synthase tetramerisation domain DFRP_C PF16543.5 KNE00589.1 - 7.3e-21 74.5 12.5 7.3e-21 74.5 12.5 4.0 4 1 0 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 KNE00589.1 - 1.9e-05 24.5 0.6 1.9e-05 24.5 0.6 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KNE00589.1 - 4.5e-05 23.1 2.1 4.5e-05 23.1 2.1 2.9 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KNE00589.1 - 8.1e-05 22.5 6.5 8.1e-05 22.5 6.5 3.1 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 KNE00589.1 - 0.00022 21.9 21.8 0.00075 20.2 7.9 4.3 2 1 1 3 3 3 2 Torus domain zf-CCCH_2 PF14608.6 KNE00589.1 - 0.0029 18.0 11.7 0.088 13.3 5.6 2.8 2 1 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KNE00589.1 - 0.0057 16.8 3.6 0.21 11.8 0.5 2.8 1 1 1 2 2 2 1 Zinc-finger containing family MOR2-PAG1_N PF14222.6 KNE00590.1 - 4.5e-150 501.2 2.5 8.7e-150 500.3 2.5 1.5 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KNE00590.1 - 4.1e-89 298.8 1.4 1.5e-88 297.0 0.1 2.6 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KNE00590.1 - 5.1e-22 77.5 17.1 1.6e-08 32.7 4.0 4.8 2 2 1 3 3 3 3 Cell morphogenesis central region Cnd1 PF12717.7 KNE00590.1 - 0.25 11.4 6.9 0.77 9.8 0.2 3.8 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 MMS19_N PF14500.6 KNE00591.1 - 1.3e-77 260.9 6.4 1.3e-77 260.9 6.4 2.8 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 KNE00591.1 - 1.5e-74 251.6 21.3 4.7e-73 246.7 6.0 5.2 5 1 1 6 6 6 2 RNAPII transcription regulator C-terminal HEAT_2 PF13646.6 KNE00591.1 - 8e-06 26.2 2.1 0.81 10.1 0.0 4.3 5 0 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 KNE00591.1 - 0.047 14.2 4.7 23 5.6 0.0 6.0 7 1 0 7 7 7 0 HEAT-like repeat HEAT PF02985.22 KNE00591.1 - 0.089 13.1 0.5 56 4.4 0.0 4.6 3 0 0 3 3 3 0 HEAT repeat ParcG PF10274.9 KNE00591.1 - 0.22 11.6 1.8 5 7.2 0.0 3.6 3 0 0 3 3 3 0 Parkin co-regulated protein DUF4042 PF13251.6 KNE00591.1 - 0.32 10.7 4.3 3.5 7.3 0.2 3.8 4 1 0 4 4 4 0 Domain of unknown function (DUF4042) DUF4404 PF14357.6 KNE00591.1 - 3.7 8.3 6.6 0.58 10.8 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Vac14_Fab1_bd PF12755.7 KNE00591.1 - 4.1 8.1 5.8 3.3 8.4 0.6 3.7 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region RRT14 PF17075.5 KNE00592.1 - 5.2e-46 157.3 13.4 6.9e-46 156.9 13.4 1.1 1 0 0 1 1 1 1 Regular of rDNA transcription protein 14 DUF4639 PF15479.6 KNE00592.1 - 0.062 12.3 0.7 0.07 12.1 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) RGS-like PF09128.11 KNE00592.1 - 0.41 10.3 6.7 0.36 10.5 5.1 1.7 1 1 1 2 2 2 0 Regulator of G protein signalling-like domain SCP2 PF02036.17 KNE00593.1 - 6.3e-23 81.2 3.0 7.3e-23 81.0 3.0 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KNE00593.1 - 3.1e-05 24.3 0.4 3.9e-05 23.9 0.4 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal WD40 PF00400.32 KNE00594.1 - 6.9e-08 33.0 0.0 0.15 13.0 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNE00594.1 - 3e-05 24.2 0.1 0.74 10.2 0.0 4.1 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KNE00594.1 - 0.0089 14.4 0.0 3.5 5.8 0.0 3.0 2 1 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Utp8 PF10395.9 KNE00594.1 - 0.11 11.0 0.2 3 6.3 0.1 2.1 1 1 0 2 2 2 0 Utp8 family DUF948 PF06103.11 KNE00595.1 - 0.28 11.5 1.3 32 4.9 0.0 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.12 KNE00595.1 - 2.2 9.0 7.5 26 5.5 0.4 3.2 3 1 0 3 3 3 0 SlyX Cation_ATPase_C PF00689.21 KNE00596.1 - 1.4e-46 158.5 6.7 1.4e-46 158.5 6.7 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KNE00596.1 - 3.3e-40 137.5 0.4 3.3e-40 137.5 0.4 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KNE00596.1 - 3.3e-22 78.4 0.0 6.6e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KNE00596.1 - 1.6e-14 54.7 1.1 2e-13 51.1 1.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KNE00596.1 - 2.7e-12 46.2 0.1 2.4e-11 43.1 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KNE00596.1 - 0.0015 18.3 0.3 0.0076 16.0 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cys_Met_Meta_PP PF01053.20 KNE00598.1 - 1.9e-139 464.5 0.1 2.1e-139 464.3 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KNE00598.1 - 3.9e-06 26.4 0.0 0.00042 19.7 0.0 2.4 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 KNE00598.1 - 0.00036 19.2 0.0 0.00057 18.5 0.0 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.21 KNE00598.1 - 0.00095 18.4 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KNE00598.1 - 0.006 15.9 0.0 0.016 14.5 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Cytochrom_C1 PF02167.15 KNE00599.1 - 5.8e-95 317.2 0.0 7e-95 316.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KNE00599.1 - 0.0019 18.4 0.0 0.0048 17.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KNE00599.1 - 0.011 16.8 0.2 0.051 14.7 0.2 2.1 2 1 0 2 2 2 0 Cytochrome c Sugar_tr PF00083.24 KNE00601.1 - 2.2e-107 359.8 26.9 2.5e-107 359.6 26.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNE00601.1 - 5.7e-27 94.6 35.5 4.4e-25 88.4 25.8 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF2583 PF10762.9 KNE00601.1 - 5.5 7.5 7.7 1.1 9.8 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2583) Pkinase PF00069.25 KNE00603.1 - 2.6e-63 213.9 0.0 3.2e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE00603.1 - 4.1e-30 104.9 0.0 5.9e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KNE00603.1 - 0.0081 15.5 0.3 0.027 13.8 0.3 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KNE00603.1 - 0.015 14.3 0.1 0.028 13.4 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KNE00603.1 - 0.092 11.8 0.2 0.25 10.4 0.2 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 APH PF01636.23 KNE00603.1 - 0.099 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTR1 PF03239.14 KNE00604.1 - 9.5e-82 274.6 10.2 1.1e-81 274.4 10.2 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF4229 PF14012.6 KNE00604.1 - 1.4 9.1 12.6 2.5 8.3 0.3 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF4229) ParBc PF02195.18 KNE00605.1 - 1.9e-13 50.5 0.0 2.4e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain NAD_binding_6 PF08030.12 KNE00606.1 - 1.1e-19 71.1 0.0 2.2e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KNE00606.1 - 1.4e-18 67.2 15.6 1.4e-18 67.2 15.6 2.5 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KNE00606.1 - 1.9e-17 63.3 0.0 8.7e-17 61.2 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain Suf PF05843.14 KNE00607.1 - 6.2e-15 55.9 23.8 1.5e-07 31.7 1.7 6.9 4 4 2 6 6 6 3 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KNE00607.1 - 2.8e-12 46.4 5.1 2.2 9.3 0.0 9.0 8 1 2 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 KNE00607.1 - 0.00025 21.5 0.0 0.075 13.6 0.0 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KNE00607.1 - 0.0018 18.4 0.3 4.3 7.8 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat HBS1_N PF08938.10 KNE00607.1 - 0.049 13.9 0.6 6 7.3 0.2 3.3 3 0 0 3 3 3 0 HBS1 N-terminus HAT PF02184.16 KNE00607.1 - 0.071 13.1 39.7 0.33 10.9 0.4 9.4 9 2 0 9 9 9 0 HAT (Half-A-TPR) repeat U3_assoc_6 PF08640.11 KNE00607.1 - 0.83 9.8 19.0 0.58 10.3 1.4 5.2 5 1 0 5 5 5 0 U3 small nucleolar RNA-associated protein 6 TPR_2 PF07719.17 KNE00607.1 - 0.93 9.8 10.3 25 5.3 0.0 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat ubiquitin PF00240.23 KNE00608.1 - 8.3e-23 79.9 0.1 9.3e-23 79.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KNE00608.1 - 7.8e-14 51.3 0.1 8.5e-14 51.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KNE00608.1 - 0.0073 16.3 0.1 1.7 8.7 0.1 2.0 2 0 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 KNE00608.1 - 0.01 15.7 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KNE00608.1 - 0.1 13.0 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_2 PF14560.6 KNE00608.1 - 0.15 12.5 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain MAJIN PF15077.6 KNE00609.1 - 1.9 8.2 9.9 2 8.1 9.9 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein CDC45 PF02724.14 KNE00609.1 - 3.8 5.7 7.8 3.7 5.7 7.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 KNE00609.1 - 5.5 5.3 14.0 5.6 5.3 14.0 1.0 1 0 0 1 1 1 0 Mpp10 protein Presenilin PF01080.17 KNE00609.1 - 9.9 4.8 5.9 10 4.8 5.9 1.1 1 0 0 1 1 1 0 Presenilin ABC2_membrane PF01061.24 KNE00610.1 - 5.4e-84 280.8 62.3 1.2e-44 152.2 20.0 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KNE00610.1 - 6e-39 133.7 0.0 1.6e-18 67.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KNE00610.1 - 1.5e-34 117.8 7.6 2.8e-30 104.1 0.0 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KNE00610.1 - 1.4e-20 73.7 0.0 3.7e-20 72.3 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 KNE00610.1 - 7.9e-08 32.4 0.0 1.7e-05 24.8 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KNE00610.1 - 4.1e-06 26.5 0.1 0.00033 20.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KNE00610.1 - 1.4e-05 25.5 0.1 0.0005 20.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KNE00610.1 - 4.6e-05 23.1 0.3 0.053 13.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KNE00610.1 - 0.00011 22.8 0.7 0.055 14.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain SMC_N PF02463.19 KNE00610.1 - 0.00029 20.3 0.0 0.53 9.7 0.0 3.3 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 KNE00610.1 - 0.00071 18.8 13.5 0.00071 18.8 13.5 3.4 2 1 1 3 3 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 KNE00610.1 - 0.00076 19.4 0.0 1.7 8.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KNE00610.1 - 0.0017 18.6 1.1 0.075 13.3 0.1 3.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KNE00610.1 - 0.0031 17.8 0.7 0.029 14.6 0.2 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KNE00610.1 - 0.0046 16.9 6.5 1 9.2 0.1 3.8 4 0 0 4 4 3 1 NACHT domain AAA_30 PF13604.6 KNE00610.1 - 0.0054 16.5 0.2 0.89 9.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KNE00610.1 - 0.0096 16.5 0.1 0.24 12.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KNE00610.1 - 0.012 15.7 0.1 0.83 9.8 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 KNE00610.1 - 0.016 15.6 0.3 14 6.1 0.1 3.3 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KNE00610.1 - 0.043 13.5 0.1 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 KNE00610.1 - 0.063 13.1 0.0 0.48 10.2 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase cobW PF02492.19 KNE00610.1 - 0.065 12.8 2.6 2.6 7.6 0.6 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KNE00610.1 - 0.073 13.2 0.1 2.1 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KNE00610.1 - 0.13 12.1 0.5 5.1 7.0 0.1 2.9 3 0 0 3 3 3 0 NTPase ABC_ATPase PF09818.9 KNE00610.1 - 0.19 10.5 0.2 2.1 7.0 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Thg1C PF14413.6 KNE00611.1 - 1.3e-48 164.1 1.4 1.8e-48 163.7 1.4 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.12 KNE00611.1 - 8.6e-47 158.3 0.2 1.7e-46 157.3 0.1 1.5 2 0 0 2 2 2 1 tRNAHis guanylyltransferase Vta1 PF04652.16 KNE00613.1 - 0.015 15.2 0.6 0.031 14.2 0.0 1.7 2 0 0 2 2 2 0 Vta1 like DUF1041 PF06292.17 KNE00613.1 - 0.067 13.6 0.4 0.22 11.9 0.4 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) NPBW PF15180.6 KNE00613.1 - 0.096 12.5 0.2 0.3 11.0 0.2 1.8 2 0 0 2 2 2 0 Neuropeptides B and W ADK_lid PF05191.14 KNE00613.1 - 0.45 10.5 3.2 2.2 8.3 3.2 2.2 1 1 0 1 1 1 0 Adenylate kinase, active site lid PWI PF01480.17 KNE00615.1 - 6.6e-07 29.6 0.8 2.2e-06 27.9 0.8 1.9 1 0 0 1 1 1 1 PWI domain DUF2303 PF10065.9 KNE00619.1 - 0.021 14.0 0.2 0.022 13.9 0.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) DUF3052 PF11253.8 KNE00619.1 - 0.29 11.1 7.1 0.31 11.0 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) L31 PF09784.9 KNE00625.1 - 2.5e-41 140.2 2.9 2.8e-41 140.1 2.9 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Spc24 PF08286.11 KNE00626.1 - 1.5e-23 83.0 14.4 3.4e-22 78.7 6.0 2.3 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 DUF3847 PF12958.7 KNE00626.1 - 0.007 16.5 0.8 0.007 16.5 0.8 2.6 1 1 2 3 3 3 1 Protein of unknown function (DUF3847) XhlA PF10779.9 KNE00626.1 - 0.022 15.0 1.9 0.022 15.0 1.9 2.5 2 0 0 2 2 2 0 Haemolysin XhlA ABC_tran_CTD PF16326.5 KNE00626.1 - 0.022 15.0 3.5 0.022 15.0 3.5 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain Swi5 PF07061.11 KNE00626.1 - 0.024 14.7 1.8 0.024 14.7 1.8 2.6 2 1 0 2 2 2 0 Swi5 DUF4140 PF13600.6 KNE00626.1 - 0.027 14.9 5.7 0.068 13.6 1.3 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.6 KNE00626.1 - 0.038 13.3 7.4 0.057 12.8 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HIP1_clath_bdg PF16515.5 KNE00626.1 - 0.042 14.4 3.2 0.042 14.4 3.2 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Exonuc_VII_L PF02601.15 KNE00626.1 - 0.084 12.4 8.0 0.1 12.1 8.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FlxA PF14282.6 KNE00626.1 - 0.1 12.6 19.4 1.4 8.9 6.3 2.7 1 1 1 2 2 2 0 FlxA-like protein Prefoldin_2 PF01920.20 KNE00626.1 - 0.11 12.4 12.3 0.17 11.8 3.2 2.6 2 0 0 2 2 2 0 Prefoldin subunit Raptor_N PF14538.6 KNE00626.1 - 0.2 11.6 1.8 0.47 10.4 1.8 1.7 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain BST2 PF16716.5 KNE00626.1 - 0.2 12.2 11.5 0.38 11.4 2.7 2.4 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DUF5082 PF16888.5 KNE00626.1 - 0.21 11.9 10.0 0.49 10.7 2.0 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) Lipoprotein_20 PF13942.6 KNE00626.1 - 0.28 11.1 10.0 0.085 12.8 3.9 2.3 1 1 1 2 2 2 0 YfhG lipoprotein FAM76 PF16046.5 KNE00626.1 - 0.3 10.4 7.4 2.5 7.4 1.6 2.1 2 0 0 2 2 2 0 FAM76 protein Taxilin PF09728.9 KNE00626.1 - 0.3 10.2 16.8 10 5.2 16.1 2.0 1 1 0 1 1 1 0 Myosin-like coiled-coil protein Pox_A_type_inc PF04508.12 KNE00626.1 - 0.45 10.5 2.1 0.56 10.2 0.1 2.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Remorin_C PF03763.13 KNE00626.1 - 0.63 9.9 10.3 0.31 10.9 0.4 2.2 2 0 0 2 2 2 0 Remorin, C-terminal region Atg14 PF10186.9 KNE00626.1 - 0.72 8.9 14.4 3.2 6.8 14.4 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 KNE00626.1 - 0.97 9.8 16.8 20 5.5 16.5 2.2 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) NPV_P10 PF05531.12 KNE00626.1 - 1.1 9.8 9.2 5.9 7.4 7.1 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4094 PF13334.6 KNE00626.1 - 1.7 9.1 7.1 0.15 12.5 0.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) CCDC-167 PF15188.6 KNE00626.1 - 2.3 8.6 8.0 19 5.7 8.0 2.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 LMBR1 PF04791.16 KNE00626.1 - 2.7 6.8 7.2 3.2 6.5 7.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.12 KNE00626.1 - 3.4 7.7 10.8 0.5 10.4 1.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) YjcZ PF13990.6 KNE00626.1 - 3.6 6.9 10.0 6.5 6.0 2.6 2.1 1 1 1 2 2 2 0 YjcZ-like protein UPF0242 PF06785.11 KNE00626.1 - 3.8 7.6 14.3 6.2 6.9 14.3 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF489 PF04356.12 KNE00626.1 - 3.9 7.5 10.2 0.61 10.1 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF489) SlyX PF04102.12 KNE00626.1 - 4.5 8.0 10.2 1 10.0 2.5 2.6 2 1 1 3 3 3 0 SlyX Jnk-SapK_ap_N PF09744.9 KNE00626.1 - 4.7 7.4 16.3 0.41 10.9 5.1 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Spc7 PF08317.11 KNE00626.1 - 5 5.9 17.6 1.4 7.7 4.8 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF5320 PF17253.2 KNE00626.1 - 5.5 8.1 7.3 1.1 10.3 1.4 2.4 2 1 1 3 3 2 0 Family of unknown function (DUF5320) SKA1 PF07160.12 KNE00626.1 - 5.7 6.7 16.4 0.98 9.2 3.8 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 V_ATPase_I PF01496.19 KNE00626.1 - 5.9 4.7 11.8 10 3.9 11.8 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 KNE00626.1 - 7.2 6.5 11.3 0.68 9.7 1.2 3.0 2 1 0 2 2 2 0 Septum formation initiator Cdh1_DBD_1 PF18196.1 KNE00626.1 - 7.3 6.9 13.0 0.54 10.6 2.4 2.6 1 1 1 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Cmc1 PF08583.10 KNE00627.1 - 6e-16 58.2 6.6 1e-15 57.5 6.6 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.9 KNE00627.1 - 0.0071 16.6 0.4 0.0093 16.2 0.4 1.3 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DASH_Hsk3 PF08227.11 KNE00628.1 - 2.1e-12 47.2 1.1 2.8e-12 46.8 1.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Hap4_Hap_bind PF10297.9 KNE00630.1 - 7.2e-07 29.1 10.3 7.2e-07 29.1 10.3 2.3 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 LRR_8 PF13855.6 KNE00631.1 - 1.2e-14 53.8 38.4 0.00011 21.8 7.0 9.4 7 2 3 10 10 10 6 Leucine rich repeat LRR_4 PF12799.7 KNE00631.1 - 3.7e-12 46.2 52.3 0.00032 21.0 2.3 10.3 4 2 7 12 12 12 8 Leucine Rich repeats (2 copies) FNIP PF05725.12 KNE00631.1 - 2.5e-08 34.0 16.9 0.021 15.0 0.0 7.7 7 0 0 7 7 7 3 FNIP Repeat LRR_9 PF14580.6 KNE00631.1 - 3.2e-05 23.5 6.9 2.2 7.8 2.1 4.3 3 1 1 4 4 4 2 Leucine-rich repeat LRR_5 PF13306.6 KNE00631.1 - 5.3e-05 23.2 3.3 0.0021 18.0 0.1 3.6 3 1 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KNE00631.1 - 0.0057 16.6 43.5 0.97 9.7 0.1 13.0 16 0 0 16 16 16 1 Leucine Rich repeat LRR_1 PF00560.33 KNE00631.1 - 9.1 7.3 44.9 22 6.1 0.0 12.8 13 2 1 14 14 14 0 Leucine Rich Repeat CcmD PF04995.14 KNE00632.1 - 0.26 11.4 3.0 0.59 10.3 3.0 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Sdh_cyt PF01127.22 KNE00634.1 - 4.1e-28 97.9 1.4 4.7e-28 97.7 1.4 1.0 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit FYVE PF01363.21 KNE00635.1 - 5.1e-16 58.6 6.7 1e-15 57.6 6.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 KNE00635.1 - 0.012 15.8 8.9 0.03 14.5 8.9 1.7 1 0 0 1 1 1 0 AN1-like Zinc finger CBFB_NFYA PF02045.15 KNE00635.1 - 0.053 14.2 0.1 0.32 11.6 0.1 2.4 1 0 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B STT3 PF02516.14 KNE00636.1 - 1.3e-155 519.1 40.7 6.1e-152 507.0 37.6 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit DUF962 PF06127.11 KNE00637.1 - 1.4e-24 86.0 0.1 2.6e-24 85.1 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF4084 PF13321.6 KNE00637.1 - 0.075 12.6 2.8 0.25 10.8 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4084) MT-A70 PF05063.14 KNE00638.1 - 4.6e-47 160.1 0.1 7.3e-47 159.5 0.1 1.3 1 0 0 1 1 1 1 MT-A70 SHD1 PF03983.12 KNE00639.1 - 7.6e-32 109.0 0.0 1.3e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.28 KNE00639.1 - 5.4e-31 106.0 11.7 2.8e-11 42.8 0.2 4.3 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 KNE00639.1 - 1.9e-28 98.1 9.6 9.3e-11 41.4 0.2 4.1 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 KNE00639.1 - 2.4e-23 81.6 0.1 1e-07 31.5 0.0 4.4 4 0 0 4 4 4 3 Variant SH3 domain SAM_4 PF18017.1 KNE00639.1 - 0.00031 20.7 0.0 0.00063 19.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) 2-Hacid_dh_C PF02826.19 KNE00640.1 - 2.3e-40 137.9 0.0 3.8e-40 137.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KNE00640.1 - 3.4e-09 36.5 0.0 4.1e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 KNE00640.1 - 0.00021 21.8 0.0 0.00055 20.5 0.0 1.7 2 0 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 KNE00640.1 - 0.0007 19.2 0.1 0.0016 18.0 0.0 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 KNE00640.1 - 0.0026 18.0 0.0 0.0054 16.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 KNE00640.1 - 0.0034 17.6 0.0 0.006 16.8 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain AdoHcyase_NAD PF00670.21 KNE00640.1 - 0.0051 16.9 0.0 0.0092 16.1 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ApbA PF02558.16 KNE00640.1 - 0.0059 16.3 0.0 0.0099 15.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 KNE00640.1 - 0.036 13.3 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 KNE00640.1 - 0.074 13.5 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_binding_7 PF13241.6 KNE00640.1 - 0.079 13.4 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 KNE00640.1 - 0.17 12.4 0.0 0.33 11.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase COX5B PF01215.19 KNE00641.1 - 4.9e-52 175.0 0.1 5.7e-52 174.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 KNE00641.1 - 0.0027 17.7 2.8 0.0043 17.1 2.8 1.3 1 0 0 1 1 1 1 Zinc-finger domain Kelch_3 PF13415.6 KNE00641.1 - 0.078 13.3 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Galactose oxidase, central domain Ribosomal_S26e PF01283.19 KNE00642.1 - 1.1e-52 177.0 10.5 1.2e-52 176.8 10.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e WD40 PF00400.32 KNE00644.1 - 1.3e-10 41.7 1.0 0.019 15.8 0.1 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNE00644.1 - 0.0041 17.4 0.1 8 6.8 0.0 4.1 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain NOA36 PF06524.12 KNE00644.1 - 0.28 10.5 3.7 0.45 9.8 3.7 1.3 1 0 0 1 1 1 0 NOA36 protein UPF0239 PF06783.11 KNE00645.1 - 0.17 12.1 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) LicD PF04991.13 KNE00646.1 - 1.1e-30 107.5 11.1 8.3e-26 91.5 0.9 3.3 3 1 1 4 4 4 2 LicD family RGS12_usC PF16612.5 KNE00648.1 - 0.056 13.9 0.0 0.061 13.8 0.0 1.1 1 0 0 1 1 1 0 C-terminal unstructured region of RGS12 ATE_C PF04377.15 KNE00649.1 - 6.5e-50 169.2 0.0 1.3e-49 168.3 0.0 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KNE00649.1 - 1.2e-23 83.3 2.3 2.6e-23 82.2 2.3 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus TFIIF_beta_N PF17683.1 KNE00650.1 - 2.8e-37 128.4 2.3 5.9e-37 127.4 2.3 1.6 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 KNE00650.1 - 1e-28 99.2 1.6 1.4e-28 98.8 0.7 1.7 2 0 0 2 2 2 1 TFIIF, beta subunit HTH domain Tau95 PF09734.9 KNE00650.1 - 0.0017 19.2 1.6 0.0063 17.3 1.5 2.1 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Prp18 PF02840.15 KNE00651.1 - 1.3e-32 112.9 0.1 1.3e-32 112.9 0.1 2.2 2 0 0 2 2 2 1 Prp18 domain Pex24p PF06398.11 KNE00652.1 - 1.7e-96 323.4 5.8 2e-96 323.2 5.8 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF986 PF06173.12 KNE00652.1 - 0.064 13.3 4.9 1.1 9.3 4.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF986) Wzy_C PF04932.15 KNE00652.1 - 0.071 12.7 4.8 2.8 7.6 1.1 2.3 2 0 0 2 2 2 0 O-Antigen ligase SMC_N PF02463.19 KNE00653.1 - 1.3e-72 243.8 0.6 5.1e-71 238.6 0.6 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KNE00653.1 - 2.7e-17 63.2 0.9 1.1e-16 61.2 0.1 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain EzrA PF06160.12 KNE00653.1 - 1.7e-05 23.3 26.6 1.7e-05 23.3 26.6 6.1 4 1 1 6 6 6 3 Septation ring formation regulator, EzrA AAA_21 PF13304.6 KNE00653.1 - 4.2e-05 23.5 0.2 4.2e-05 23.5 0.2 4.8 3 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KNE00653.1 - 5.2e-05 23.1 25.0 5.2e-05 23.1 25.0 4.5 2 2 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 KNE00653.1 - 6.3e-05 22.6 0.0 0.00015 21.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Nup54 PF13874.6 KNE00653.1 - 0.012 15.7 0.4 0.012 15.7 0.4 7.5 3 2 2 5 5 5 0 Nucleoporin complex subunit 54 AAA_23 PF13476.6 KNE00653.1 - 0.6 10.6 125.4 0.86 10.1 53.6 6.8 2 2 1 3 3 3 0 AAA domain NPV_P10 PF05531.12 KNE00653.1 - 1.2 9.6 40.7 1.9 9.0 0.7 9.3 6 2 4 10 10 10 0 Nucleopolyhedrovirus P10 protein DUF3135 PF11333.8 KNE00653.1 - 2.6 8.4 10.0 20 5.5 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3135) Anp1 PF03452.14 KNE00654.1 - 3.2e-112 374.2 0.0 4.3e-112 373.8 0.0 1.1 1 0 0 1 1 1 1 Anp1 RhoGAP PF00620.27 KNE00655.1 - 2.9e-39 134.3 0.0 7.8e-39 132.9 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain NRBF2 PF08961.10 KNE00655.1 - 0.0015 18.1 2.1 0.0066 16.1 2.1 2.2 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator CtIP_N PF10482.9 KNE00655.1 - 0.054 13.5 3.6 0.22 11.6 3.7 2.1 1 1 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain YabA PF06156.13 KNE00655.1 - 0.092 13.4 8.0 0.19 12.4 6.4 2.5 1 1 0 1 1 1 0 Initiation control protein YabA DUF1708 PF08101.11 KNE00655.1 - 0.097 11.8 0.0 0.097 11.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1708) TMF_TATA_bd PF12325.8 KNE00655.1 - 0.51 10.6 15.5 0.53 10.5 0.7 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding ZapB PF06005.12 KNE00655.1 - 0.79 10.2 11.3 0.35 11.4 5.6 2.8 1 1 1 2 2 2 0 Cell division protein ZapB TMCO5 PF14992.6 KNE00655.1 - 1.7 8.2 10.2 5.6 6.5 10.3 1.8 2 0 0 2 2 2 0 TMCO5 family JIP_LZII PF16471.5 KNE00655.1 - 5.7 7.2 10.9 0.61 10.3 3.8 2.5 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II APG6_N PF17675.1 KNE00655.1 - 8.5 6.9 10.2 10 6.7 6.1 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region IGPD PF00475.18 KNE00657.1 - 4.7e-59 198.8 0.6 6.9e-59 198.3 0.6 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase SpoU_methylase PF00588.19 KNE00658.1 - 4.4e-22 78.8 0.0 7.9e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KNE00658.1 - 5.8e-15 55.3 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding DUF3106 PF11304.8 KNE00658.1 - 0.17 12.3 2.5 0.52 10.8 2.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) Aa_trans PF01490.18 KNE00659.1 - 2.2e-61 207.8 27.9 2.6e-61 207.6 27.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Med14 PF08638.11 KNE00660.1 - 1.6e-56 190.8 0.1 4.6e-56 189.3 0.1 1.9 1 0 0 1 1 1 1 Mediator complex subunit MED14 Pkinase PF00069.25 KNE00662.1 - 1.6e-38 132.6 0.0 2.6e-38 131.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE00662.1 - 2e-18 66.6 0.0 1.3e-11 44.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KNE00662.1 - 0.037 13.4 0.0 3.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Kinase-like DUF454 PF04304.13 KNE00665.1 - 0.12 12.4 3.1 1.3 9.1 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF454) WD40 PF00400.32 KNE00666.1 - 8.7e-08 32.7 2.4 0.0036 18.1 0.1 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNE00666.1 - 0.0002 21.6 0.0 10 6.5 0.0 4.3 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KNE00666.1 - 0.029 13.7 0.0 0.064 12.6 0.0 1.6 2 0 0 2 2 2 0 WD40-like domain PQQ_3 PF13570.6 KNE00666.1 - 0.05 14.1 2.6 17 6.1 0.0 4.1 5 0 0 5 5 5 0 PQQ-like domain SET PF00856.28 KNE00668.1 - 1.3e-14 54.9 0.2 5.9e-14 52.8 0.0 2.0 2 0 0 2 2 2 1 SET domain Lipoprotein_10 PF03202.13 KNE00668.1 - 0.03 14.7 1.3 3.8 8.0 0.1 2.5 2 0 0 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region YpjP PF14005.6 KNE00668.1 - 0.048 13.7 0.8 18 5.4 0.0 3.2 2 1 1 3 3 3 0 YpjP-like protein CX9C PF16860.5 KNE00669.1 - 0.016 15.2 0.8 0.025 14.6 0.8 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DB PF01682.19 KNE00669.1 - 0.037 14.3 0.1 0.039 14.2 0.1 1.1 1 0 0 1 1 1 0 DB module Cmc1 PF08583.10 KNE00669.1 - 0.049 13.7 0.3 0.068 13.2 0.3 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHASE9 PF17153.4 KNE00670.1 - 0.055 13.6 0.1 0.34 11.1 0.0 2.2 2 0 0 2 2 2 0 Periplasmic sensor domain, extracellular Cyclin_N PF00134.23 KNE00671.1 - 2.5e-21 75.7 0.0 5.9e-21 74.5 0.0 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KNE00671.1 - 1.5e-10 41.7 1.2 5.8e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 Cyclin Zn_clus PF00172.18 KNE00673.1 - 1.5e-09 37.8 10.5 2.9e-09 36.9 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KNE00673.1 - 2e-08 33.6 0.1 3.9e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain HTH_57 PF18679.1 KNE00673.1 - 0.17 12.2 0.2 0.71 10.2 0.0 2.1 2 0 0 2 2 2 0 ThcOx helix turn helix domain Fungal_trans PF04082.18 KNE00674.1 - 7.3e-10 38.3 0.6 1.4e-09 37.3 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain TIMELESS PF04821.14 KNE00676.1 - 9.8e-75 251.4 3.6 8.3e-73 245.0 0.4 2.4 2 0 0 2 2 2 2 Timeless protein MCM6_C PF18263.1 KNE00676.1 - 0.0065 16.7 0.3 0.033 14.4 0.3 2.2 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain Aa_trans PF01490.18 KNE00677.1 - 1.7e-72 244.4 29.8 2e-72 244.1 29.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein rRNA_processing PF08524.11 KNE00678.1 - 1.4e-33 116.0 36.6 6.7e-33 113.8 36.6 1.8 1 1 0 1 1 1 1 rRNA processing SpoIIIAH PF12685.7 KNE00678.1 - 0.026 14.4 16.6 0.034 14.0 16.6 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein XRCC4 PF06632.12 KNE00678.1 - 0.18 10.7 17.9 0.26 10.1 17.9 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 BLOC1S3 PF15753.5 KNE00678.1 - 0.29 11.3 11.6 0.45 10.6 11.6 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 CDC45 PF02724.14 KNE00678.1 - 0.86 7.8 19.3 1.1 7.5 19.3 1.1 1 0 0 1 1 1 0 CDC45-like protein GREB1 PF15782.5 KNE00678.1 - 7.5 3.5 10.5 8.3 3.4 10.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ABC1 PF03109.16 KNE00679.1 - 9.7e-35 119.3 0.0 1.9e-34 118.4 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 KNE00679.1 - 3.8e-05 23.4 0.0 0.00027 20.6 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Zn_clus PF00172.18 KNE00680.1 - 3e-07 30.4 9.6 3e-07 30.4 9.6 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MALT1_Ig PF18703.1 KNE00680.1 - 0.21 11.6 1.3 1.3 9.0 0.5 2.6 3 0 0 3 3 3 0 MALT1 Ig-like domain Dickkopf_N PF04706.12 KNE00680.1 - 3.5 8.2 7.8 8.7 6.9 7.8 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region LSM PF01423.22 KNE00681.1 - 5e-15 54.9 0.5 5.9e-15 54.7 0.5 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KNE00681.1 - 0.0005 20.1 0.2 0.00078 19.5 0.1 1.4 1 1 1 2 2 2 1 Ataxin 2 SM domain ANAPC9 PF12856.7 KNE00682.1 - 2.8e-16 59.7 1.0 1.9e-14 53.9 1.0 3.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 9 Glutaredoxin PF00462.24 KNE00685.1 - 4.2e-12 46.1 0.0 9.6e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin Peptidase_C93 PF06035.11 KNE00685.1 - 0.025 14.4 0.4 0.059 13.2 0.3 1.7 2 1 0 2 2 2 0 Bacterial transglutaminase-like cysteine proteinase BTLCP Malate_synthase PF01274.22 KNE00688.1 - 4.3e-227 754.5 0.0 4.9e-227 754.4 0.0 1.0 1 0 0 1 1 1 1 Malate synthase CMAS PF02353.20 KNE00689.1 - 3.1e-57 193.9 0.2 3.9e-57 193.6 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KNE00689.1 - 7.6e-11 42.1 0.0 1.6e-10 41.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNE00689.1 - 1.6e-09 38.3 0.0 2.9e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNE00689.1 - 5.9e-08 33.3 0.0 1.1e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNE00689.1 - 3.1e-05 24.6 0.0 5.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNE00689.1 - 8.3e-05 22.4 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain COX7C PF02935.16 KNE00689.1 - 0.00032 20.9 2.1 0.0011 19.2 2.1 1.9 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc DOT1 PF08123.13 KNE00689.1 - 0.0016 18.0 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 FtsJ PF01728.19 KNE00689.1 - 0.0059 16.7 0.0 0.0097 16.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase VOMI PF03762.17 KNE00689.1 - 0.0071 16.5 0.1 0.011 15.9 0.1 1.2 1 0 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) MTS PF05175.14 KNE00689.1 - 0.032 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain SIR2 PF02146.17 KNE00691.1 - 8.5e-65 218.0 0.0 1.3e-64 217.3 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 KNE00691.1 - 3.6e-26 91.8 4.6 1.4e-12 47.6 1.6 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 KNE00691.1 - 1.5e-05 24.8 0.1 0.019 14.7 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain zf-RING_7 PF02591.15 KNE00691.1 - 0.03 14.5 0.6 0.1 12.8 0.6 2.0 1 0 0 1 1 1 0 C4-type zinc ribbon domain HypA PF01155.19 KNE00691.1 - 0.098 12.7 0.4 0.23 11.5 0.3 1.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF836 PF05768.14 KNE00691.1 - 0.12 12.8 0.0 0.42 11.0 0.0 1.9 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KNE00691.1 - 0.38 11.0 1.3 1.6 9.0 0.1 2.6 2 0 0 2 2 2 0 Glutaredoxin HLH PF00010.26 KNE00693.1 - 1.9e-16 59.7 0.0 3.5e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3263 PF11662.8 KNE00693.1 - 0.0069 16.2 0.4 1.8 8.4 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3263) PAPS_reduct PF01507.19 KNE00694.1 - 2.4e-20 73.3 0.0 6.4e-18 65.4 0.0 2.1 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family SF3A2 PF16835.5 KNE00696.1 - 1.1e-25 89.9 1.7 4.1e-25 88.0 1.7 1.9 1 1 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KNE00696.1 - 2.2e-07 31.0 0.4 6.4e-07 29.6 0.4 1.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Ank_2 PF12796.7 KNE00697.1 - 2e-06 28.3 1.6 0.024 15.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KNE00697.1 - 0.00065 20.0 0.0 0.97 10.0 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KNE00697.1 - 0.0021 18.6 0.2 9.4 6.9 0.0 3.9 4 1 1 5 5 5 2 Ankyrin repeats (many copies) KilA-N PF04383.13 KNE00697.1 - 0.021 14.6 1.0 0.06 13.2 0.0 2.3 2 0 0 2 2 2 0 KilA-N domain Ank_3 PF13606.6 KNE00697.1 - 0.39 11.4 1.9 75 4.4 0.0 4.0 4 0 0 4 4 4 0 Ankyrin repeat EF-hand_6 PF13405.6 KNE00698.1 - 4.5e-16 57.4 4.5 2.3e-05 23.9 0.4 5.1 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 KNE00698.1 - 3.3e-14 53.1 8.2 9.4e-08 32.4 0.1 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KNE00698.1 - 5.2e-13 47.5 7.0 6.5e-06 25.3 0.3 5.4 4 1 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KNE00698.1 - 8.2e-08 32.0 2.6 0.00055 19.7 2.7 4.1 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_4 PF12763.7 KNE00698.1 - 0.00019 21.4 0.6 0.29 11.1 0.1 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 KNE00698.1 - 0.0023 17.3 12.6 0.28 10.7 0.0 4.9 6 0 0 6 6 6 2 EF hand S10_plectin PF03501.15 KNE00698.1 - 0.028 14.5 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 Plectin/S10 domain EF-hand_9 PF14658.6 KNE00698.1 - 0.14 12.5 1.5 5.3 7.4 0.2 3.3 3 1 0 3 3 3 0 EF-hand domain Sdh5 PF03937.16 KNE00699.1 - 6.7e-27 93.3 1.9 1.1e-26 92.6 1.9 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase HTH_24 PF13412.6 KNE00699.1 - 0.069 12.7 0.4 2.2 7.9 0.1 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Vta1 PF04652.16 KNE00700.1 - 2.5e-32 111.8 1.0 4.7e-32 110.9 0.1 1.8 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 KNE00700.1 - 9.8e-17 60.4 0.0 1.9e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Vta1 C-terminal domain DUF438 PF04282.13 KNE00700.1 - 0.00086 19.2 1.6 0.0077 16.2 0.4 2.4 2 0 0 2 2 2 1 Family of unknown function (DUF438) Slu7 PF11708.8 KNE00701.1 - 1.5e-18 67.5 13.2 1.4e-16 61.1 13.2 2.2 1 1 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor PFEMP PF03011.15 KNE00701.1 - 0.18 12.4 11.8 2.2 8.9 2.1 2.3 2 0 0 2 2 2 0 PFEMP DBL domain Nop52 PF05997.12 KNE00702.1 - 2.2e-67 227.0 6.4 3.1e-67 226.5 6.4 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 CFIA_Pcf11 PF11526.8 KNE00702.1 - 0.0059 17.1 4.2 0.013 16.0 4.2 1.6 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 BUD22 PF09073.10 KNE00702.1 - 0.0095 15.3 7.1 0.0095 15.3 7.1 1.9 3 0 0 3 3 3 1 BUD22 CPSF100_C PF13299.6 KNE00702.1 - 0.034 14.4 1.2 0.055 13.6 1.2 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal MOR2-PAG1_N PF14222.6 KNE00702.1 - 0.14 11.1 0.7 0.27 10.2 0.1 1.6 2 0 0 2 2 2 0 Cell morphogenesis N-terminal RRN3 PF05327.11 KNE00702.1 - 0.18 10.3 8.4 0.32 9.5 8.4 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Astro_capsid_p PF12226.8 KNE00702.1 - 0.3 10.2 4.6 0.42 9.7 4.6 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CobT PF06213.12 KNE00702.1 - 1.1 8.6 12.1 0.1 12.0 7.6 1.5 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF4637 PF15470.6 KNE00702.1 - 1.1 9.0 9.0 2 8.1 9.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Sporozoite_P67 PF05642.11 KNE00702.1 - 1.4 6.9 9.1 2.1 6.4 9.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.10 KNE00702.1 - 2.7 8.4 25.2 0.11 12.9 15.2 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 KNE00702.1 - 2.9 5.9 28.2 0.2 9.7 23.1 1.5 2 0 0 2 2 2 0 DNA polymerase phi SecE PF00584.20 KNE00703.1 - 0.0013 18.6 0.0 0.0015 18.4 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex ATP13 PF12921.7 KNE00704.1 - 7.8e-23 80.5 0.3 2.2e-22 79.1 0.1 2.0 2 0 0 2 2 2 1 Mitochondrial ATPase expression CCSMST1 PF15013.6 KNE00704.1 - 0.075 13.2 1.8 0.099 12.8 0.1 2.1 2 0 0 2 2 2 0 CCSMST1 family DUF4252 PF14060.6 KNE00704.1 - 0.13 12.1 0.2 1.3 8.9 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4252) ECH_1 PF00378.20 KNE00705.1 - 1.1e-23 83.9 0.0 1.6e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KNE00705.1 - 1.2e-20 74.3 0.0 1.5e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DEAD PF00270.29 KNE00706.1 - 2.5e-50 170.7 0.0 9.2e-50 168.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNE00706.1 - 1.8e-25 89.4 0.0 9.5e-25 87.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNE00706.1 - 0.0021 18.1 0.0 0.0069 16.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AA_permease PF00324.21 KNE00707.1 - 3.1e-48 164.6 39.0 4.1e-48 164.2 39.0 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KNE00707.1 - 5.7e-13 48.7 9.3 3.9e-06 26.2 0.0 3.8 4 0 0 4 4 4 3 Solute carrier family 12 TAF6_C PF07571.13 KNE00711.1 - 7e-28 96.8 0.0 1.9e-27 95.4 0.0 1.8 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KNE00711.1 - 1.7e-25 88.9 0.0 1.8e-24 85.6 0.0 2.5 3 0 0 3 3 3 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 KNE00711.1 - 0.00024 21.5 0.6 0.027 14.8 0.1 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KNE00711.1 - 0.0058 16.9 0.2 0.017 15.4 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF348 PF03990.14 KNE00711.1 - 0.23 11.2 1.2 2 8.3 0.0 2.6 2 1 0 2 2 2 0 G5-linked-Ubiquitin-like domain PXA PF02194.15 KNE00711.1 - 0.61 10.0 3.4 12 5.9 0.0 3.0 2 1 1 3 3 3 0 PXA domain SLD3 PF08639.10 KNE00712.1 - 9.6e-22 77.4 16.8 3.4e-20 72.3 16.8 2.2 1 1 0 1 1 1 1 DNA replication regulator SLD3 Pkinase PF00069.25 KNE00713.1 - 1.8e-56 191.5 0.0 3e-56 190.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE00713.1 - 6.1e-21 74.9 0.0 9.4e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNE00713.1 - 2e-06 27.3 0.0 3.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PAS PF00989.25 KNE00713.1 - 0.0018 18.3 0.0 1.6 8.8 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KNE00713.1 - 0.0019 18.4 0.1 0.06 13.6 0.0 3.0 3 0 0 3 3 3 1 PAS domain Kdo PF06293.14 KNE00713.1 - 0.0023 17.3 0.0 0.0064 15.9 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KNE00713.1 - 0.008 16.1 0.1 0.016 15.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KNE00713.1 - 0.024 14.3 0.6 0.1 12.2 0.3 2.0 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KNE00713.1 - 0.032 13.0 0.0 0.074 11.8 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KNE00713.1 - 0.16 11.6 0.5 0.41 10.2 0.5 1.6 1 0 0 1 1 1 0 RIO1 family LDB19 PF13002.7 KNE00714.1 - 5.4e-57 192.6 0.3 8.6e-57 192.0 0.3 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 KNE00714.1 - 0.17 11.9 0.2 0.51 10.4 0.0 1.9 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Actin PF00022.19 KNE00716.1 - 1.9e-62 211.2 0.0 4.2e-61 206.8 0.0 2.0 1 1 0 1 1 1 1 Actin PIG-L PF02585.17 KNE00718.1 - 2.4e-23 83.2 0.0 3.4e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Methyltransf_11 PF08241.12 KNE00719.1 - 2.8e-16 59.9 0.0 5.6e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNE00719.1 - 1.5e-14 54.4 0.0 3.4e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNE00719.1 - 1.2e-13 51.2 0.0 1.8e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNE00719.1 - 1.6e-12 48.0 0.0 3.4e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KNE00719.1 - 1.5e-10 40.8 0.0 2.5e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KNE00719.1 - 2.7e-07 30.6 0.0 3.5e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KNE00719.1 - 0.00061 19.4 0.0 0.0039 16.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KNE00719.1 - 0.011 15.7 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.18 KNE00720.1 - 3.7e-34 118.0 0.4 1e-33 116.6 0.4 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNE00720.1 - 3e-10 40.1 11.7 6.5e-10 39.0 11.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HhH-GPD PF00730.25 KNE00721.1 - 4.4e-18 65.7 0.0 9.4e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF356 PF04009.12 KNE00721.1 - 8.9e-05 22.7 0.3 0.00017 21.8 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF356) HHH PF00633.23 KNE00721.1 - 0.00012 21.8 0.0 0.00025 20.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif DNA_primase_S PF01896.19 KNE00721.1 - 0.032 14.3 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 DNA primase small subunit Pro_sub2 PF18513.1 KNE00721.1 - 0.18 12.0 0.0 0.48 10.6 0.0 1.6 1 0 0 1 1 1 0 Prodomain subtilisin 2 Exo_endo_phos PF03372.23 KNE00722.1 - 5.5e-15 55.5 0.0 8e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KNE00722.1 - 0.023 14.5 0.1 0.1 12.5 0.1 2.1 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase AFOR_N PF02730.15 KNE00722.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain YolD PF08863.10 KNE00723.1 - 0.13 12.3 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 YolD-like protein Exo_endo_phos PF03372.23 KNE00724.1 - 4.2e-23 82.1 0.0 3.5e-22 79.1 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 KNE00724.1 - 8.4e-15 54.3 9.1 3.1e-09 36.4 1.0 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KNE00724.1 - 8.6e-12 45.1 8.9 8.2e-07 29.3 0.5 2.9 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KNE00724.1 - 0.0006 20.0 7.7 6.6 7.7 0.0 5.4 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 KNE00724.1 - 0.028 14.4 5.1 2.7 8.3 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich repeat Exo_endo_phos_2 PF14529.6 KNE00724.1 - 0.081 12.8 0.4 1.7 8.5 0.4 2.8 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase His_Phos_1 PF00300.22 KNE00725.1 - 1.1e-05 25.2 0.2 1.1e-05 25.2 0.2 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AF0941-like PF14591.6 KNE00725.1 - 0.1 13.2 0.1 0.26 11.9 0.1 1.7 1 0 0 1 1 1 0 AF0941-like Sugar_tr PF00083.24 KNE00726.1 - 7.7e-29 100.8 33.6 5.3e-19 68.4 11.5 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KNE00726.1 - 5.2e-19 68.4 37.7 5.7e-11 41.9 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_2 PF04909.14 KNE00729.1 - 1.6e-06 28.2 0.0 2.4e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 KNE00729.1 - 2.9e-05 23.5 0.0 4.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family DIM1 PF02966.16 KNE00731.1 - 1.4e-68 228.8 0.7 1.5e-68 228.6 0.7 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 DUF3192 PF11399.8 KNE00731.1 - 0.038 13.9 0.1 0.056 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) PBP PF01161.20 KNE00732.1 - 1.5e-23 83.6 0.3 2e-23 83.1 0.3 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein CBFD_NFYB_HMF PF00808.23 KNE00734.1 - 8.8e-19 67.6 1.0 1.4e-18 66.9 1.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KNE00734.1 - 1.3e-16 61.1 0.2 2.2e-16 60.4 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KNE00734.1 - 0.028 14.7 0.1 0.055 13.8 0.1 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X PMT PF02366.18 KNE00735.1 - 1.6e-78 263.7 20.2 1.6e-78 263.7 20.2 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KNE00735.1 - 9.1e-56 188.6 13.8 9.1e-56 188.6 13.8 2.8 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KNE00735.1 - 4.9e-19 68.9 0.0 1.2e-18 67.7 0.0 1.5 1 1 0 1 1 1 1 MIR domain CENP-K PF11802.8 KNE00735.1 - 0.14 11.7 0.1 0.23 11.0 0.1 1.2 1 0 0 1 1 1 0 Centromere-associated protein K PhzC-PhzF PF02567.16 KNE00736.1 - 1.4e-55 188.8 0.0 1.6e-55 188.6 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 KNE00736.1 - 2.1e-09 36.9 0.0 5.4e-07 29.0 0.0 2.3 2 1 0 2 2 2 2 Proline racemase HrpB4 PF09502.10 KNE00737.1 - 0.053 13.3 0.0 0.06 13.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB4) Mcp5_PH PF12814.7 KNE00739.1 - 1.2e-41 141.7 0.6 4.4e-41 139.8 0.6 2.1 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.12 KNE00739.1 - 3.2e-06 27.2 4.1 3.2e-06 27.2 4.1 4.9 2 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein PH PF00169.29 KNE00739.1 - 0.00041 20.8 0.1 0.0017 18.8 0.1 2.2 1 0 0 1 1 1 1 PH domain Jnk-SapK_ap_N PF09744.9 KNE00739.1 - 0.0056 16.9 6.4 0.0056 16.9 6.4 6.7 5 1 1 6 6 6 1 JNK_SAPK-associated protein-1 RILP PF11461.8 KNE00739.1 - 0.028 14.6 4.1 0.27 11.5 4.1 2.9 1 0 0 1 1 1 0 Rab interacting lysosomal protein DUF2757 PF10955.8 KNE00739.1 - 0.21 11.9 1.6 32 4.9 0.1 4.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) bZIP_1 PF00170.21 KNE00739.1 - 0.32 11.1 25.0 0.72 10.0 3.7 5.6 5 0 0 5 5 5 0 bZIP transcription factor Tup_N PF08581.10 KNE00739.1 - 0.33 11.3 23.2 0.0096 16.2 1.8 7.0 4 1 2 6 6 6 0 Tup N-terminal RNase_Zc3h12a PF11977.8 KNE00739.1 - 6.2 6.6 15.2 0.67 9.7 0.0 6.5 8 0 0 8 8 8 0 Zc3h12a-like Ribonuclease NYN domain KxDL PF10241.9 KNE00739.1 - 9.6 6.6 9.6 15 5.9 3.4 4.7 2 1 1 3 3 3 0 Uncharacterized conserved protein EF-hand_1 PF00036.32 KNE00740.1 - 3.6e-28 95.0 4.3 9.5e-09 34.2 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KNE00740.1 - 4e-25 88.1 0.8 2.7e-16 59.8 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KNE00740.1 - 1.6e-24 85.5 3.1 4.1e-10 39.3 0.1 3.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KNE00740.1 - 1.2e-21 75.2 4.2 4.8e-08 32.1 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KNE00740.1 - 1.4e-17 62.1 3.3 1.7e-08 33.7 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_9 PF14658.6 KNE00740.1 - 5.9e-09 36.1 0.2 0.00037 20.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KNE00740.1 - 4.6e-07 29.7 1.9 0.0043 17.0 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KNE00740.1 - 8.4e-07 29.3 0.1 7.6e-05 23.0 0.0 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KNE00740.1 - 1.8e-06 28.1 4.8 0.0011 19.2 1.1 3.0 1 1 2 3 3 3 3 Dockerin type I domain UPF0154 PF03672.13 KNE00740.1 - 1.4e-05 25.0 0.0 0.23 11.5 0.0 2.8 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 KNE00740.1 - 0.00036 21.4 0.0 0.04 14.8 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 KNE00740.1 - 0.00061 19.8 0.4 0.0065 16.4 0.1 2.0 1 1 0 2 2 2 1 Tellurite resistance protein TerB EF-hand_10 PF14788.6 KNE00740.1 - 0.0085 15.9 0.7 0.019 14.8 0.1 1.8 2 1 0 2 2 2 1 EF hand Poly_export PF02563.16 KNE00740.1 - 0.0092 16.2 0.0 0.034 14.4 0.0 1.9 1 1 1 2 2 2 1 Polysaccharide biosynthesis/export protein DUF5580 PF17743.1 KNE00740.1 - 0.041 12.4 0.0 0.043 12.4 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 KNE00740.1 - 0.082 13.3 0.1 0.25 11.7 0.1 1.9 1 1 0 2 2 2 0 EF-hand domain Spore_III_AB PF09548.10 KNE00740.1 - 0.1 12.7 0.1 0.14 12.3 0.1 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) IMS PF00817.20 KNE00742.1 - 4.9e-36 124.0 0.1 3.1e-35 121.4 0.0 2.3 2 0 0 2 2 2 1 impB/mucB/samB family BRCT_2 PF16589.5 KNE00742.1 - 7.1e-12 45.6 0.0 1.8e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_C PF11799.8 KNE00742.1 - 2.2e-11 44.5 0.0 7e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain LIG3_BRCT PF16759.5 KNE00742.1 - 2.2e-06 27.8 0.0 6.1e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT PF00533.26 KNE00742.1 - 0.00035 20.9 0.0 0.0011 19.3 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain REV1_C PF16727.5 KNE00742.1 - 0.00043 20.6 0.0 0.0012 19.2 0.0 1.8 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain Glycos_transf_1 PF00534.20 KNE00743.1 - 3.7e-10 39.6 0.0 5.3e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KNE00743.1 - 1.4e-09 38.5 0.0 3.2e-09 37.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KNE00743.1 - 0.00035 20.6 0.0 0.00055 20.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KNE00743.1 - 0.0064 16.9 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 zf-CCCH PF00642.24 KNE00744.1 - 8.2e-10 38.3 2.0 1.8e-09 37.3 2.0 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_UBOX PF13445.6 KNE00744.1 - 1.1e-09 38.2 6.1 4.1e-08 33.1 6.9 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KNE00744.1 - 1.2e-08 34.6 8.7 2.7e-08 33.5 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KNE00744.1 - 1.8e-06 28.1 11.3 4.1e-06 27.0 11.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KNE00744.1 - 2.2e-06 27.5 12.7 6.4e-06 26.0 12.7 1.8 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KNE00744.1 - 2.2e-06 27.4 10.1 8e-06 25.6 10.0 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KNE00744.1 - 4.7e-06 26.3 11.1 4.7e-06 26.3 11.1 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 KNE00744.1 - 4.9e-06 26.4 4.7 1e-05 25.4 4.7 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4 PF00097.25 KNE00744.1 - 2.2e-05 24.2 12.3 5.2e-05 23.0 12.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KNE00744.1 - 2.8e-05 24.2 10.2 6.3e-05 23.0 10.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-CCCH_4 PF18044.1 KNE00744.1 - 0.00075 19.2 1.5 0.0021 17.8 1.5 1.8 1 0 0 1 1 1 1 CCCH-type zinc finger zf-RING_6 PF14835.6 KNE00744.1 - 0.051 13.4 3.2 0.096 12.6 3.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 KNE00744.1 - 0.078 12.8 9.0 0.16 11.8 9.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KNE00744.1 - 0.47 10.3 11.6 3.2 7.6 0.5 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 KNE00744.1 - 0.58 10.3 7.4 1.8 8.8 7.4 1.8 1 1 0 1 1 1 0 zinc RING finger of MSL2 DUF4112 PF13430.6 KNE00745.1 - 3.8e-21 75.3 0.3 4.8e-21 75.0 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) CTP_transf_like PF01467.26 KNE00746.1 - 1.3e-30 106.5 0.0 2.1e-16 60.4 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 KNE00746.1 - 0.006 16.5 0.0 0.27 11.1 0.0 2.3 2 0 0 2 2 2 2 FAD synthetase HABP4_PAI-RBP1 PF04774.15 KNE00747.1 - 0.00088 20.1 0.7 0.00088 20.1 0.7 1.6 1 1 1 2 2 2 1 Hyaluronan / mRNA binding family RWD PF05773.22 KNE00748.1 - 7.6e-16 58.4 0.3 2.4e-15 56.8 0.1 1.9 2 0 0 2 2 2 1 RWD domain IBR PF01485.21 KNE00748.1 - 1.6e-15 57.1 33.4 2.3e-08 34.1 4.0 4.3 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 KNE00748.1 - 1.6e-05 24.8 7.5 1.6e-05 24.8 7.5 3.5 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 KNE00748.1 - 5.7e-05 23.0 9.4 5.7e-05 23.0 9.4 4.4 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KNE00748.1 - 7.5e-05 22.5 5.4 7.5e-05 22.5 5.4 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KNE00748.1 - 0.00019 21.7 8.5 0.00019 21.7 8.5 4.4 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 KNE00748.1 - 0.0002 21.1 6.2 0.0002 21.1 6.2 4.9 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KNE00748.1 - 0.006 16.3 6.1 0.006 16.3 6.1 2.3 2 0 0 2 2 2 1 RING-like zinc finger FYVE PF01363.21 KNE00748.1 - 0.92 9.7 29.9 0.13 12.5 1.6 3.5 3 0 0 3 3 3 0 FYVE zinc finger CN_hydrolase PF00795.22 KNE00749.1 - 2.6e-18 66.3 0.0 1e-15 57.8 0.0 3.0 3 0 0 3 3 3 3 Carbon-nitrogen hydrolase Rav1p_C PF12234.8 KNE00750.1 - 1.1e-212 708.0 6.1 1.9e-212 707.2 6.1 1.4 1 0 0 1 1 1 1 RAVE protein 1 C terminal MFS_1 PF07690.16 KNE00751.1 - 4.9e-11 42.2 48.3 4.6e-08 32.4 29.7 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily UNC-93 PF05978.16 KNE00751.1 - 5.1e-06 26.3 6.4 5.1e-06 26.3 6.4 2.9 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 Pyridoxal_deC PF00282.19 KNE00753.1 - 2.1e-74 250.5 0.0 2.6e-74 250.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KNE00753.1 - 8.8e-06 24.9 0.0 1.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KNE00753.1 - 0.00032 20.1 0.0 0.00044 19.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KNE00753.1 - 0.074 12.3 0.0 0.091 12.1 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family ING PF12998.7 KNE00754.1 - 0.055 14.1 0.0 0.063 13.9 0.0 1.1 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding MMS1_N PF10433.9 KNE00755.1 - 2.3e-90 303.6 1.5 4.6e-90 302.6 1.5 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KNE00755.1 - 1e-65 222.2 0.6 3e-65 220.6 0.2 2.1 2 0 0 2 2 2 1 CPSF A subunit region Forkhead PF00250.18 KNE00756.1 - 6.3e-36 122.5 1.1 1.2e-35 121.7 1.1 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KNE00756.1 - 6.3e-08 32.9 0.0 1.5e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Linker_histone PF00538.19 KNE00756.1 - 0.053 13.9 0.3 0.2 12.0 0.1 2.0 2 0 0 2 2 2 0 linker histone H1 and H5 family WD40 PF00400.32 KNE00757.1 - 1.7e-09 38.1 6.9 0.072 14.0 0.9 6.2 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNE00757.1 - 4.5e-07 30.1 1.1 0.061 13.6 0.0 4.5 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KNE00757.1 - 5.2e-07 29.7 2.8 0.02 14.8 0.8 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A ArsA_HSP20 PF17886.1 KNE00757.1 - 0.069 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 HSP20-like domain found in ArsA DUF4852 PF16144.5 KNE00757.1 - 0.77 9.9 4.9 1.9 8.7 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4852) EMP24_GP25L PF01105.24 KNE00758.1 - 3.8e-36 124.7 0.0 4.9e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Vps8 PF12816.7 KNE00759.1 - 7.2e-50 169.2 3.3 7.2e-50 169.2 3.3 2.2 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 WD40 PF00400.32 KNE00759.1 - 0.0039 18.0 0.1 0.046 14.6 0.0 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat zf-RING_2 PF13639.6 KNE00759.1 - 0.17 12.2 7.6 0.086 13.2 3.6 2.4 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 KNE00759.1 - 0.34 10.9 6.1 0.2 11.6 3.3 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KNE00759.1 - 0.6 10.0 3.6 1.7 8.5 3.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KNE00759.1 - 2.6 8.4 7.6 0.16 12.3 1.9 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain Chitin_synth_1 PF01644.17 KNE00760.1 - 3e-64 215.9 0.1 4.4e-64 215.4 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KNE00760.1 - 7.8e-24 83.4 0.0 1.9e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KNE00760.1 - 1.7e-22 79.8 3.9 8.6e-18 64.2 0.0 3.3 3 2 1 4 4 4 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KNE00760.1 - 1.5e-14 54.4 3.7 1.5e-14 54.4 3.7 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KNE00760.1 - 0.0015 18.4 0.0 0.004 17.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KNE00760.1 - 0.01 15.6 0.0 2.9 7.7 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KNE00760.1 - 0.012 15.1 0.0 0.096 12.1 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 21 ANAPC3 PF12895.7 KNE00761.1 - 0.18 12.0 1.6 9.5 6.5 0.1 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 E1-E2_ATPase PF00122.20 KNE00763.1 - 6.4e-48 162.7 8.0 1.9e-47 161.1 6.9 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KNE00763.1 - 2.8e-19 70.3 0.1 5.8e-19 69.2 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KNE00763.1 - 3e-10 39.6 0.0 6.6e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KNE00763.1 - 0.0031 17.3 0.1 0.0031 17.3 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KNE00763.1 - 0.022 14.8 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) UreE_N PF02814.15 KNE00763.1 - 0.07 12.7 0.1 4.6 6.9 0.0 2.5 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain O-antigen_lig PF13425.6 KNE00763.1 - 3.2 6.5 11.1 0.27 10.0 5.6 1.9 2 0 0 2 2 2 0 O-antigen ligase like membrane protein PUF PF00806.19 KNE00765.1 - 1.3e-61 200.9 2.2 1.2e-08 34.1 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat HTH_16 PF12645.7 KNE00765.1 - 0.2 11.7 0.0 0.76 9.9 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Fungal_trans_2 PF11951.8 KNE00766.1 - 5.9e-12 45.1 0.6 6.9e-11 41.6 0.8 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNE00766.1 - 2.1e-09 37.3 12.8 4e-09 36.5 12.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ERG4_ERG24 PF01222.17 KNE00767.1 - 2.2e-158 527.6 23.7 2.4e-158 527.4 23.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Proteasome PF00227.26 KNE00768.1 - 1.8e-33 115.6 0.1 2.1e-33 115.4 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Tudor_2 PF18104.1 KNE00768.1 - 0.17 11.6 0.5 0.47 10.2 0.5 1.7 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain Hist_deacetyl PF00850.19 KNE00769.1 - 4e-82 276.1 0.0 5.4e-82 275.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Pkinase PF00069.25 KNE00770.1 - 2.2e-53 181.3 0.9 3.1e-53 180.8 0.9 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE00770.1 - 9.4e-32 110.3 0.1 1.9e-31 109.3 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNE00770.1 - 0.0004 19.8 0.0 0.0029 17.0 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KNE00770.1 - 0.00045 19.1 0.0 0.00077 18.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Tricorn_C1 PF14684.6 KNE00770.1 - 0.13 12.3 0.1 0.33 11.0 0.1 1.7 1 0 0 1 1 1 0 Tricorn protease C1 domain Rhodanese PF00581.20 KNE00772.1 - 8.3e-09 35.9 0.0 1.8e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain adh_short PF00106.25 KNE00774.1 - 5.8e-86 286.9 10.2 8.8e-46 155.8 1.3 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KNE00774.1 - 4.7e-71 239.1 3.8 7.3e-38 130.4 0.2 3.1 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 KNE00774.1 - 5.2e-33 113.2 0.0 1.1e-32 112.2 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 KNE00774.1 - 2.2e-32 112.4 3.1 1.8e-15 57.4 0.2 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KNE00774.1 - 0.18 11.2 1.8 7.4 5.9 0.2 2.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GCIP PF13324.6 KNE00774.1 - 0.38 10.3 4.3 0.68 9.5 4.3 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting RNA_pol_3_Rpc31 PF11705.8 KNE00774.1 - 1 9.6 8.2 1.9 8.7 8.2 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PglL_A PF15864.5 KNE00774.1 - 1.8 8.4 7.6 8.1 6.3 0.8 2.4 2 0 0 2 2 2 0 Protein glycosylation ligase NOA36 PF06524.12 KNE00774.1 - 4 6.7 12.1 6.1 6.1 12.1 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KNE00774.1 - 7.4 4.5 11.4 10 4.0 11.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi TFIIA PF03153.13 KNE00774.1 - 7.6 6.4 7.6 12 5.8 7.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 KNE00774.1 - 8.1 5.7 7.9 13 5.0 7.9 1.2 1 0 0 1 1 1 0 BUD22 Dicty_REP PF05086.12 KNE00774.1 - 9.1 4.1 6.3 13 3.6 6.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2457 PF10446.9 KNE00774.1 - 9.5 5.2 11.7 14 4.7 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Acyltransferase PF01553.21 KNE00776.1 - 2.2e-09 37.0 0.0 1.1e-08 34.7 0.0 2.1 1 1 0 1 1 1 1 Acyltransferase Rtf2 PF04641.12 KNE00776.1 - 0.0092 15.4 1.4 0.016 14.6 1.4 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger CAF20 PF17052.5 KNE00776.1 - 0.011 15.9 0.5 0.027 14.7 0.5 1.7 1 0 0 1 1 1 0 Cap associated factor DNA_ligase_A_M PF01068.21 KNE00777.1 - 5.1e-62 209.2 0.1 8.1e-62 208.5 0.1 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KNE00777.1 - 2.4e-46 158.2 0.1 8.7e-46 156.4 0.0 2.0 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KNE00777.1 - 3.9e-25 88.3 0.0 8.7e-25 87.2 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KNE00777.1 - 0.00039 20.8 0.0 0.00077 19.8 0.0 1.5 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 KNE00777.1 - 0.097 12.7 0.3 21 5.2 0.1 2.8 2 0 0 2 2 2 0 DNA ligase OB-like domain Actin PF00022.19 KNE00778.1 - 5.4e-23 81.3 0.0 3e-22 78.8 0.0 1.8 1 1 0 1 1 1 1 Actin ChpXY PF10216.9 KNE00779.1 - 0.01 15.0 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 CO2 hydration protein (ChpXY) ABC_membrane PF00664.23 KNE00779.1 - 0.087 12.5 1.4 0.13 11.9 1.4 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region Eisosome1 PF12757.7 KNE00780.1 - 1.2e-19 70.8 6.5 1.2e-19 70.8 6.5 7.3 3 1 4 7 7 7 1 Eisosome protein 1 GHMP_kinases_N PF00288.26 KNE00780.1 - 0.024 14.9 1.8 0.085 13.1 1.8 2.0 1 0 0 1 1 1 0 GHMP kinases N terminal domain Histone PF00125.24 KNE00783.1 - 4.3e-43 146.8 0.0 4.6e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KNE00783.1 - 0.00032 21.0 0.0 0.00045 20.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KNE00783.1 - 0.00066 19.8 0.0 0.001 19.2 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KNE00783.1 - 0.0054 17.0 0.5 0.01 16.1 0.5 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KNE00783.1 - 0.008 16.2 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit zf-C2H2 PF00096.26 KNE00784.1 - 4.2e-13 49.0 13.4 9.1e-07 29.0 1.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KNE00784.1 - 3.1e-09 36.9 13.0 0.00015 22.3 1.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KNE00784.1 - 5.9e-09 36.0 7.4 0.00029 21.0 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KNE00784.1 - 2.9e-08 33.8 20.1 7.7e-06 26.1 5.3 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 KNE00784.1 - 1.7e-05 24.7 10.6 0.011 15.7 3.8 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KNE00784.1 - 2.5e-05 24.5 4.3 0.22 11.9 2.3 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KNE00784.1 - 0.00011 22.6 10.0 0.07 13.6 0.7 2.5 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-BED PF02892.15 KNE00784.1 - 0.00025 21.0 5.0 0.018 15.1 0.8 2.6 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_2 PF12756.7 KNE00784.1 - 0.0022 18.3 5.1 0.14 12.5 1.0 2.3 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-AN1 PF01428.16 KNE00784.1 - 0.028 14.6 2.7 1.8 8.8 0.3 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger zf-Di19 PF05605.12 KNE00784.1 - 0.029 14.6 6.0 0.029 14.6 6.0 2.0 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 KNE00784.1 - 0.038 13.8 1.0 1.7 8.5 0.8 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf_UBZ PF18439.1 KNE00784.1 - 0.19 11.3 3.2 2.1 8.0 0.3 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger FOXP-CC PF16159.5 KNE00784.1 - 0.36 11.5 3.5 3.1 8.5 0.3 2.6 2 0 0 2 2 2 0 FOXP coiled-coil domain Actin_micro PF17003.5 KNE00784.1 - 0.46 9.6 4.9 7.5 5.6 4.9 2.3 1 1 0 1 1 1 0 Putative actin-like family Zn-ribbon_8 PF09723.10 KNE00784.1 - 0.57 10.3 3.4 4.5 7.5 0.5 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_5 PF13909.6 KNE00784.1 - 1 9.2 18.6 1.7 8.5 5.5 3.2 2 1 0 2 2 2 0 C2H2-type zinc-finger domain DUF629 PF04780.12 KNE00784.1 - 2.5 6.5 6.2 8.5 4.8 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF629) PyrI_C PF02748.15 KNE00784.1 - 5.2 7.1 8.7 0.26 11.2 0.8 2.9 3 1 1 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf_C2H2_ZHX PF18387.1 KNE00784.1 - 8.6 6.1 9.5 4.5 7.0 0.2 2.8 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain SBF_like PF13593.6 KNE00787.1 - 3.6e-121 404.3 17.3 4.1e-121 404.1 17.3 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Colicin_im PF03857.13 KNE00787.1 - 0.67 9.9 8.0 0.06 13.3 2.7 1.9 2 0 0 2 2 2 0 Colicin immunity protein FCH PF00611.23 KNE00789.1 - 4.1e-11 43.0 0.4 5.6e-10 39.4 0.3 2.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KNE00789.1 - 8.5e-10 38.1 0.1 1.5e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KNE00789.1 - 8.1e-07 28.8 0.1 1.6e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KNE00789.1 - 0.00016 21.3 0.1 0.00031 20.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain C12orf66_like PF09404.10 KNE00789.1 - 0.03 13.2 4.9 0.049 12.5 4.9 1.2 1 0 0 1 1 1 0 KICSTOR complex C12orf66 like Aldo_ket_red PF00248.21 KNE00790.1 - 3.8e-42 144.5 0.0 4.8e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PC4 PF02229.16 KNE00791.1 - 9.4e-22 76.4 0.9 1.7e-21 75.5 0.9 1.5 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) CorA PF01544.18 KNE00792.1 - 1.1e-35 123.4 3.4 1.6e-17 63.8 0.1 3.6 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein Bap31 PF05529.12 KNE00793.1 - 9.9e-34 116.1 4.4 1.6e-33 115.4 4.4 1.3 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KNE00793.1 - 1.7e-07 31.1 5.9 1.7e-07 31.1 5.9 1.9 3 0 0 3 3 3 1 Bap31/Bap29 cytoplasmic coiled-coil domain Cep57_MT_bd PF06657.13 KNE00793.1 - 0.0088 16.5 1.8 0.016 15.7 1.8 1.4 1 0 0 1 1 1 1 Centrosome microtubule-binding domain of Cep57 Mod_r PF07200.13 KNE00793.1 - 0.036 14.2 6.5 1.7 8.8 3.8 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein KilA-N PF04383.13 KNE00794.1 - 1.8e-05 24.5 0.0 0.00026 20.8 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain Suc_Fer-like PF06999.12 KNE00796.1 - 3e-46 157.7 0.0 3.6e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like SNF2_N PF00176.23 KNE00797.1 - 2.5e-66 223.8 0.0 6.7e-66 222.4 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KNE00797.1 - 4e-21 75.4 0.0 9.8e-21 74.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNE00797.1 - 1.5e-07 31.6 2.6 6.6e-07 29.5 0.0 3.2 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Gpr1_Fun34_YaaH PF01184.19 KNE00798.1 - 1.2e-89 299.4 17.2 1.4e-89 299.2 17.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family S_4TM PF18159.1 KNE00798.1 - 0.2 11.0 1.7 0.31 10.3 1.7 1.3 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain DUF3784 PF12650.7 KNE00798.1 - 6.7 7.0 13.1 0.63 10.3 3.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) adh_short PF00106.25 KNE00801.1 - 1.3e-42 145.5 0.0 1.7e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNE00801.1 - 2.1e-32 112.6 0.0 2.7e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNE00801.1 - 4.1e-08 33.4 0.0 7.9e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KNE00801.1 - 0.0039 16.7 0.0 0.015 14.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KNE00801.1 - 0.054 12.9 0.0 0.11 11.8 0.0 1.5 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) LDcluster4 PF18306.1 KNE00801.1 - 0.081 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 SLOG cluster4 family Pkinase PF00069.25 KNE00802.1 - 3e-56 190.7 0.0 1.7e-55 188.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE00802.1 - 1.7e-26 93.0 0.0 5.4e-19 68.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KNE00802.1 - 2.1e-05 25.1 2.6 6.6e-05 23.5 1.4 2.3 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 KNE00802.1 - 9.4e-05 21.9 0.0 0.0089 15.4 0.0 2.5 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 KNE00802.1 - 0.0017 17.4 0.0 0.0028 16.7 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KNE00802.1 - 0.0037 17.2 0.0 0.051 13.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KNE00802.1 - 0.0044 16.4 0.1 0.0083 15.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RNase_PH PF01138.21 KNE00803.1 - 9.2e-16 58.6 0.2 1.6e-15 57.8 0.2 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KNE00803.1 - 0.00017 21.5 0.0 0.00042 20.3 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Nop PF01798.18 KNE00804.1 - 2.3e-55 187.6 0.1 5.9e-55 186.2 0.0 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KNE00804.1 - 4.2e-25 89.0 4.5 9.1e-25 87.9 4.5 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain RecC_C PF17946.1 KNE00804.1 - 0.063 13.1 0.0 0.17 11.7 0.0 1.8 1 1 0 1 1 1 0 RecC C-terminal domain tRNA-synt_1 PF00133.22 KNE00805.1 - 1e-231 770.4 3.8 1.5e-230 766.6 3.8 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KNE00805.1 - 1.3e-36 125.9 0.3 1.3e-36 125.9 0.3 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KNE00805.1 - 4.1e-16 58.7 1.3 4e-08 32.4 0.1 4.9 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KNE00805.1 - 1.3e-10 41.1 16.1 8.1e-08 32.0 0.0 4.4 4 1 1 5 5 5 2 Leucyl-tRNA synthetase, Domain 2 TALPID3 PF15324.6 KNE00805.1 - 0.0028 15.4 1.1 0.0028 15.4 1.1 2.0 2 0 0 2 2 2 1 Hedgehog signalling target SPECT1 PF18680.1 KNE00805.1 - 0.11 12.2 0.0 0.11 12.2 0.0 3.1 3 0 0 3 3 3 0 Plasmodium host cell traversal SPECT1 tRNA-synt_1e PF01406.19 KNE00805.1 - 0.46 9.8 0.0 0.46 9.8 0.0 3.5 4 1 0 4 4 4 0 tRNA synthetases class I (C) catalytic domain S-antigen PF05756.11 KNE00807.1 - 0.11 12.8 1.5 0.12 12.8 1.5 1.2 1 0 0 1 1 1 0 S-antigen protein CDT1_C PF16679.5 KNE00808.1 - 2.8e-07 30.9 0.1 7.6e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain AHD PF17793.1 KNE00808.1 - 0.12 12.2 0.2 2 8.2 0.0 2.5 2 0 0 2 2 2 0 ANC1 homology domain (AHD) E1-E2_ATPase PF00122.20 KNE00809.1 - 8.8e-20 71.0 0.0 1.6e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KNE00809.1 - 6.4e-17 62.5 0.0 1.2e-09 38.7 0.1 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KNE00809.1 - 2e-05 24.6 0.0 5.2e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KNE00809.1 - 0.00098 18.9 0.2 0.003 17.3 0.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KNE00809.1 - 0.032 13.8 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase IF-2B PF01008.17 KNE00810.1 - 6.6e-55 186.3 0.0 2e-54 184.7 0.0 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family Pex2_Pex12 PF04757.14 KNE00811.1 - 1.1e-51 175.6 12.1 1.5e-51 175.1 12.1 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KNE00811.1 - 3.1e-05 24.1 3.2 6.2e-05 23.1 3.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KNE00811.1 - 0.00093 19.0 0.5 0.0017 18.1 0.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KNE00811.1 - 0.0013 18.5 1.2 0.0025 17.6 0.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KNE00811.1 - 0.0014 18.6 0.7 0.0032 17.4 0.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KNE00811.1 - 0.022 14.6 2.3 0.044 13.7 2.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KNE00811.1 - 0.084 13.2 0.6 0.22 11.9 0.6 1.7 1 0 0 1 1 1 0 Ring finger domain RXT2_N PF08595.11 KNE00811.1 - 0.21 11.6 2.2 0.29 11.1 1.0 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF4637 PF15470.6 KNE00811.1 - 8.4 6.1 7.3 16 5.2 7.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Not3 PF04065.15 KNE00813.1 - 7.9e-31 107.3 13.9 1.7e-30 106.2 13.9 1.6 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KNE00813.1 - 0.00028 21.0 0.6 1.1 9.3 0.0 2.8 2 0 0 2 2 2 2 NOT2 / NOT3 / NOT5 family DUF866 PF05907.13 KNE00813.1 - 0.024 14.5 0.2 0.078 12.9 0.2 1.8 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) CytochromB561_N PF09786.9 KNE00813.1 - 0.49 9.3 15.7 0.71 8.8 15.7 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal HSP70 PF00012.20 KNE00814.1 - 1.9e-256 852.0 18.2 2.1e-256 851.8 18.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KNE00814.1 - 2.5e-19 69.3 3.2 2e-18 66.3 1.2 2.3 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.18 KNE00814.1 - 5e-05 22.7 1.0 0.035 13.4 0.1 2.8 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase DDR PF08841.10 KNE00814.1 - 0.001 18.1 1.5 0.0066 15.5 1.5 2.1 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.6 KNE00814.1 - 0.0013 19.1 10.5 0.78 10.2 0.8 3.8 3 2 0 3 3 3 3 Cell division protein FtsA NPR2 PF06218.11 KNE00814.1 - 0.041 12.6 2.3 0.1 11.4 2.3 1.6 1 0 0 1 1 1 0 Nitrogen permease regulator 2 TENA_THI-4 PF03070.16 KNE00814.1 - 0.26 11.1 2.4 0.54 10.0 2.4 1.5 1 0 0 1 1 1 0 TENA/THI-4/PQQC family Prp19 PF08606.11 KNE00814.1 - 0.28 11.2 2.5 0.31 11.1 0.1 2.2 2 0 0 2 2 2 0 Prp19/Pso4-like BcrAD_BadFG PF01869.20 KNE00814.1 - 0.53 9.7 4.0 6.7 6.1 0.1 2.8 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family Nup54 PF13874.6 KNE00814.1 - 3.9 7.6 8.1 7 6.8 3.1 3.0 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 CREPT PF16566.5 KNE00814.1 - 4.3 7.5 12.1 2.5 8.3 7.8 2.5 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour cNMP_binding PF00027.29 KNE00815.1 - 3.5e-43 145.6 0.1 3.9e-21 74.9 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 KNE00815.1 - 3.5e-08 33.0 1.1 9.1e-08 31.6 1.1 1.8 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Erg28 PF03694.13 KNE00816.1 - 1.9e-46 157.0 0.6 2.3e-46 156.7 0.6 1.1 1 0 0 1 1 1 1 Erg28 like protein Mito_carr PF00153.27 KNE00817.1 - 3.8e-64 212.6 1.5 3.3e-21 75.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ammonium_transp PF00909.21 KNE00818.1 - 1.1e-74 251.5 26.6 2.9e-44 151.4 12.7 2.0 2 0 0 2 2 2 2 Ammonium Transporter Family PLA2_B PF01735.18 KNE00819.1 - 3.6e-95 319.2 7.1 1.7e-72 244.4 0.0 2.1 1 1 0 2 2 2 2 Lysophospholipase catalytic domain DUF1405 PF07187.11 KNE00819.1 - 0.072 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1405) ABC_tran PF00005.27 KNE00820.1 - 1.6e-45 155.0 0.8 7.2e-23 81.6 0.0 4.7 4 2 0 4 4 2 2 ABC transporter 4HB PF17947.1 KNE00820.1 - 2.8e-27 94.6 0.2 1.3e-26 92.4 0.0 2.3 2 0 0 2 2 1 1 Four helical bundle domain AAA_21 PF13304.6 KNE00820.1 - 7.6e-18 65.4 0.0 0.0052 16.6 0.0 4.6 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KNE00820.1 - 2.9e-15 56.3 0.1 2.2e-05 24.0 0.0 4.1 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KNE00820.1 - 2.5e-11 44.5 1.8 0.00036 21.1 0.0 3.6 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KNE00820.1 - 2.4e-09 37.3 0.0 0.00016 21.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KNE00820.1 - 9.7e-09 34.8 0.0 0.006 16.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 KNE00820.1 - 5.6e-08 33.2 0.0 0.0015 18.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KNE00820.1 - 1.1e-07 31.9 0.0 0.0025 17.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KNE00820.1 - 3.5e-07 30.6 0.0 0.028 14.7 0.0 4.0 4 1 0 4 4 2 2 AAA domain MMS19_C PF12460.8 KNE00820.1 - 3.9e-06 26.2 2.3 0.0032 16.6 0.4 2.4 2 0 0 2 2 2 2 RNAPII transcription regulator C-terminal AAA_15 PF13175.6 KNE00820.1 - 1.1e-05 25.4 0.0 0.095 12.4 0.0 3.7 3 1 0 3 3 2 2 AAA ATPase domain RNA_helicase PF00910.22 KNE00820.1 - 1.3e-05 25.5 0.0 0.2 12.1 0.0 3.2 3 0 0 3 3 2 2 RNA helicase Dynamin_N PF00350.23 KNE00820.1 - 1.4e-05 25.2 0.0 0.0006 19.9 0.0 2.9 2 0 0 2 2 2 1 Dynamin family AAA_18 PF13238.6 KNE00820.1 - 2.5e-05 24.8 0.0 0.56 10.8 0.0 3.2 3 0 0 3 3 2 2 AAA domain MeaB PF03308.16 KNE00820.1 - 2.9e-05 23.2 0.1 0.12 11.3 0.0 2.8 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 KNE00820.1 - 5.7e-05 23.5 0.1 0.59 10.6 0.0 4.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KNE00820.1 - 6.3e-05 23.2 0.0 0.52 10.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain DRIM PF07539.12 KNE00820.1 - 7.4e-05 21.3 2.8 0.017 13.4 0.0 2.2 2 0 0 2 2 2 2 Down-regulated in metastasis AAA_16 PF13191.6 KNE00820.1 - 0.00011 22.6 0.2 0.24 11.8 0.0 3.5 4 0 0 4 4 4 1 AAA ATPase domain SbcCD_C PF13558.6 KNE00820.1 - 0.00013 22.2 0.5 0.76 10.1 0.0 4.5 4 1 0 4 4 4 1 Putative exonuclease SbcCD, C subunit AAA_27 PF13514.6 KNE00820.1 - 0.00024 20.8 0.0 0.24 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KNE00820.1 - 0.00094 18.9 0.1 1.6 8.4 0.1 3.4 3 1 0 3 3 3 1 AAA domain DUF87 PF01935.17 KNE00820.1 - 0.00099 19.3 3.4 0.4 10.7 0.0 4.4 5 0 0 5 5 3 1 Helicase HerA, central domain AAA_24 PF13479.6 KNE00820.1 - 0.0016 18.2 0.1 1.6 8.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain PduV-EutP PF10662.9 KNE00820.1 - 0.0021 17.8 0.0 0.13 12.0 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Adaptin_N PF01602.20 KNE00820.1 - 0.0032 16.1 7.2 0.041 12.4 1.9 3.0 2 1 1 3 3 3 1 Adaptin N terminal region Rad17 PF03215.15 KNE00820.1 - 0.0039 17.2 0.0 2.1 8.2 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain NACHT PF05729.12 KNE00820.1 - 0.0043 17.0 0.1 1.1 9.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 KNE00820.1 - 0.0057 16.7 0.0 8 6.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain CLP1_P PF16575.5 KNE00820.1 - 0.0064 16.3 0.0 1.3 8.8 0.0 3.1 3 0 0 3 3 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop ATPase_2 PF01637.18 KNE00820.1 - 0.008 16.1 0.2 5.8 6.8 0.0 3.2 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea ParcG PF10274.9 KNE00820.1 - 0.0091 16.1 0.2 0.47 10.6 0.1 2.7 2 0 0 2 2 2 1 Parkin co-regulated protein cobW PF02492.19 KNE00820.1 - 0.011 15.3 0.0 5.8 6.5 0.0 2.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Cytidylate_kin PF02224.18 KNE00820.1 - 0.014 15.2 0.0 6.5 6.4 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase IstB_IS21 PF01695.17 KNE00820.1 - 0.017 14.9 0.0 3.9 7.2 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Roc PF08477.13 KNE00820.1 - 0.02 15.1 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Mg_chelatase PF01078.21 KNE00820.1 - 0.03 13.7 0.1 1.5 8.2 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Ploopntkinase3 PF18751.1 KNE00820.1 - 0.032 14.2 0.0 5.8 6.8 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 HEAT_2 PF13646.6 KNE00820.1 - 0.042 14.2 4.7 0.051 14.0 1.9 2.7 2 2 0 2 2 1 0 HEAT repeats CLASP_N PF12348.8 KNE00820.1 - 0.044 13.3 0.2 0.47 10.0 0.2 2.4 1 1 0 1 1 1 0 CLASP N terminal G-alpha PF00503.20 KNE00820.1 - 0.052 12.7 0.0 9.3 5.3 0.0 2.5 2 0 0 2 2 2 0 G-protein alpha subunit Septin PF00735.18 KNE00820.1 - 0.059 12.7 0.3 3.8 6.7 0.0 2.9 3 0 0 3 3 2 0 Septin Zeta_toxin PF06414.12 KNE00820.1 - 0.059 12.6 0.2 13 5.0 0.0 3.2 4 0 0 4 4 3 0 Zeta toxin MutS_V PF00488.21 KNE00820.1 - 0.059 13.4 0.1 6.4 6.7 0.1 2.5 2 0 0 2 2 2 0 MutS domain V AAA_7 PF12775.7 KNE00820.1 - 0.061 12.8 0.0 13 5.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 KNE00820.1 - 0.077 13.0 0.0 6.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 KNE00820.1 - 0.084 12.8 0.1 19 5.2 0.1 2.7 2 0 0 2 2 2 0 NTPase MukB PF04310.12 KNE00820.1 - 0.089 12.6 0.1 11 5.8 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal UME PF08064.13 KNE00820.1 - 0.1 12.5 0.8 0.39 10.6 0.5 2.1 1 1 1 2 2 2 0 UME (NUC010) domain ATP_bind_1 PF03029.17 KNE00820.1 - 0.13 12.1 2.3 7.8 6.2 0.1 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein RE_HindVP PF09519.10 KNE00820.1 - 0.13 11.2 0.3 0.28 10.2 0.3 1.4 1 0 0 1 1 1 0 HindVP restriction endonuclease Adeno_IVa2 PF02456.15 KNE00820.1 - 0.15 10.8 0.1 6.9 5.4 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_17 PF13207.6 KNE00820.1 - 0.45 10.9 3.1 33 4.9 0.7 3.6 2 1 0 2 2 2 0 AAA domain DUF3349 PF11829.8 KNE00820.1 - 0.96 10.3 3.8 2.1 9.2 0.1 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF3349) AAA_13 PF13166.6 KNE00820.1 - 3.5 6.2 11.0 1.6 7.3 0.0 3.8 5 0 0 5 5 5 0 AAA domain Flavoprotein PF02441.19 KNE00821.1 - 1.8e-50 170.8 0.4 2.7e-50 170.2 0.4 1.3 1 0 0 1 1 1 1 Flavoprotein Nop14 PF04147.12 KNE00821.1 - 0.57 8.3 40.1 1.1 7.3 40.1 1.4 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KNE00821.1 - 0.87 7.8 29.3 1.8 6.8 29.3 1.5 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KNE00821.1 - 1.9 7.9 44.1 3.4 7.0 44.1 1.3 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 KNE00821.1 - 2.2 6.7 29.8 4.1 5.8 29.8 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4100 PF13352.6 KNE00821.1 - 7.5 6.3 13.4 2 8.2 4.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4100) Ydc2-catalyt PF09159.10 KNE00822.1 - 6.6e-39 134.3 0.0 9.6e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 TMEM100 PF16311.5 KNE00823.1 - 9.5 5.8 6.5 3 7.4 0.4 2.1 2 0 0 2 2 2 0 Transmembrane protein 100 PLA2_B PF01735.18 KNE00826.1 - 3e-197 655.9 2.2 3.6e-197 655.7 2.2 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 KNE00826.1 - 0.017 15.3 2.9 0.031 14.5 2.9 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain TRM PF02005.16 KNE00827.1 - 1.1e-120 403.3 0.0 1.5e-120 402.8 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase DUF2067 PF09840.9 KNE00827.1 - 0.0058 16.2 0.0 0.014 15.0 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2067) GP88 PF17338.2 KNE00827.1 - 0.013 15.0 0.5 1.5 8.3 0.0 2.9 4 0 0 4 4 4 0 Gene product 88 Met_10 PF02475.16 KNE00827.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Pox_int_trans PF05718.12 KNE00827.1 - 0.16 10.7 1.4 0.19 10.4 0.0 1.7 2 0 0 2 2 2 0 Poxvirus intermediate transcription factor DHHC PF01529.20 KNE00832.1 - 7.8e-31 107.0 12.0 7.8e-31 107.0 12.0 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase CorA PF01544.18 KNE00832.1 - 0.1 11.9 1.6 0.19 11.0 1.6 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1131 PF06572.12 KNE00832.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) Virul_fac_BrkB PF03631.15 KNE00832.1 - 1.7 8.2 13.2 0.11 12.1 5.7 2.3 2 1 0 2 2 2 0 Virulence factor BrkB DREPP PF05558.12 KNE00833.1 - 0.064 13.1 3.5 0.28 11.0 0.2 2.2 2 0 0 2 2 2 0 DREPP plasma membrane polypeptide Ku_C PF03730.14 KNE00833.1 - 0.13 13.0 2.2 0.77 10.5 0.3 2.8 2 1 1 3 3 3 0 Ku70/Ku80 C-terminal arm Glyco_hydro81C PF17652.1 KNE00834.1 - 1.5e-149 498.0 4.9 2e-149 497.6 4.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KNE00834.1 - 1e-91 307.5 0.0 1.7e-91 306.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Fungal_trans PF04082.18 KNE00835.1 - 1.7e-25 89.6 3.7 1.7e-25 89.6 3.7 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNE00835.1 - 2.6e-06 27.4 11.6 4.6e-06 26.7 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ARPC4 PF05856.12 KNE00836.1 - 1.1e-14 54.3 0.3 1.2e-14 54.3 0.3 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) FF PF01846.19 KNE00837.1 - 2.9e-24 85.0 17.8 4.2e-08 33.2 0.0 5.9 6 0 0 6 6 6 4 FF domain WW PF00397.26 KNE00837.1 - 1.2e-19 70.1 14.0 5.6e-10 39.1 3.8 2.7 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 KNE00837.1 - 0.05 13.9 6.8 0.32 11.3 0.7 3.2 2 1 1 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain Apidaecin PF00807.17 KNE00837.1 - 0.11 12.7 0.3 0.2 11.8 0.3 1.4 1 0 0 1 1 1 0 Apidaecin DUF5106 PF17127.4 KNE00837.1 - 0.11 12.8 0.2 0.11 12.8 0.2 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF5106) Sortilin-Vps10 PF15902.5 KNE00840.1 - 1.2e-214 713.2 4.0 5.1e-128 427.7 0.5 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KNE00840.1 - 1.2e-71 240.5 22.0 2.8e-44 151.5 6.5 2.3 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KNE00840.1 - 2.2e-10 38.9 42.5 0.073 13.1 0.3 11.9 11 0 0 11 11 11 5 BNR/Asp-box repeat CHB_HEX_C PF03174.13 KNE00840.1 - 0.01 15.8 4.0 33 4.6 0.0 5.2 4 1 1 5 5 5 0 Chitobiase/beta-hexosaminidase C-terminal domain PSII_BNR PF14870.6 KNE00840.1 - 0.022 14.0 4.4 2.9 7.1 0.1 4.5 4 2 0 4 4 4 0 Photosynthesis system II assembly factor YCF48 Rax2 PF12768.7 KNE00841.1 - 9.1e-55 185.4 0.8 9.1e-55 185.4 0.8 3.5 4 0 0 4 4 4 1 Cortical protein marker for cell polarity DUF3642 PF12182.8 KNE00841.1 - 0.086 13.1 2.0 0.51 10.7 0.5 3.0 2 0 0 2 2 2 0 Bacterial lipoprotein TRAPPC-Trs85 PF12739.7 KNE00843.1 - 3.8e-90 302.8 4.2 4.8e-90 302.4 4.2 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF1751 PF08551.10 KNE00844.1 - 1.9e-16 60.4 2.7 1.9e-16 60.4 2.7 2.3 3 0 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KNE00844.1 - 0.5 10.4 14.5 0.095 12.7 10.7 1.7 2 0 0 2 2 2 0 Rhomboid family DUF5321 PF17254.2 KNE00845.1 - 2e-05 24.1 0.1 2.4e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5321) DUF2666 PF10869.8 KNE00845.1 - 0.055 13.7 0.2 0.11 12.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) MCM PF00493.23 KNE00846.1 - 1.6e-101 338.1 0.0 2.4e-101 337.5 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KNE00846.1 - 1.5e-37 128.3 0.1 2.9e-37 127.3 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KNE00846.1 - 9.9e-28 96.4 7.1 9.8e-27 93.2 2.7 3.3 3 0 0 3 3 3 1 MCM AAA-lid domain MCM_N PF14551.6 KNE00846.1 - 3e-20 72.7 1.4 1.1e-19 70.9 0.3 2.7 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.21 KNE00846.1 - 1.7e-06 27.6 0.0 0.00019 20.9 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KNE00846.1 - 8.3e-06 25.9 0.0 3.6e-05 23.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KNE00846.1 - 0.00022 21.1 0.0 0.0039 17.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KNE00846.1 - 0.02 14.6 0.0 2.4 7.8 0.0 3.6 4 0 0 4 4 4 0 Sigma-54 interaction domain AAA_16 PF13191.6 KNE00846.1 - 0.1 13.0 1.5 1.5 9.2 0.1 3.2 2 2 0 2 2 2 0 AAA ATPase domain AD PF09793.9 KNE00848.1 - 0.08 13.1 0.0 0.082 13.1 0.0 1.1 1 0 0 1 1 1 0 Anticodon-binding domain Ldh_1_N PF00056.23 KNE00849.1 - 1.1e-44 151.9 0.5 1.7e-44 151.4 0.5 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KNE00849.1 - 3.4e-35 121.4 0.0 6.2e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 KNE00849.1 - 0.0029 16.7 0.0 0.0044 16.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 KNE00849.1 - 0.067 12.7 0.2 3.4 7.2 0.2 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase MFS_1 PF07690.16 KNE00850.1 - 8.5e-27 94.0 26.5 8.5e-27 94.0 26.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Beta-lactamase PF00144.24 KNE00851.1 - 1.6e-51 175.5 0.0 2.2e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Histidinol_dh PF00815.20 KNE00852.1 - 3.5e-156 520.3 1.1 5.7e-156 519.6 1.1 1.3 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 KNE00852.1 - 2e-21 75.6 0.1 4.6e-21 74.4 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KNE00852.1 - 1.8e-15 57.2 0.1 5.7e-15 55.5 0.1 1.9 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 KNE00852.1 - 0.01 16.0 0.1 0.023 14.8 0.1 1.6 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain TPR_1 PF00515.28 KNE00853.1 - 1.3e-22 78.6 1.2 6.4e-06 25.8 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 KNE00853.1 - 1e-18 66.7 0.7 7.6e-06 25.5 0.0 5.6 3 1 2 5 5 5 3 TPR repeat TPR_14 PF13428.6 KNE00853.1 - 2.9e-16 58.8 2.9 0.00038 21.0 0.0 6.0 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KNE00853.1 - 3.7e-16 57.9 5.2 0.0026 17.8 0.0 6.7 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 KNE00853.1 - 4e-16 58.2 3.8 0.0024 18.1 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KNE00853.1 - 4.3e-13 48.3 1.2 0.027 14.6 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KNE00853.1 - 1.3e-12 48.2 2.0 0.0019 18.8 0.2 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KNE00853.1 - 1.5e-11 44.6 3.2 0.012 16.1 0.1 4.7 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 KNE00853.1 - 8.4e-08 32.3 0.2 0.0016 18.5 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_20 PF14561.6 KNE00853.1 - 3.2e-06 27.4 5.9 0.031 14.6 0.0 5.0 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KNE00853.1 - 6.6e-05 23.3 1.9 14 6.6 0.0 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 KNE00853.1 - 0.00025 20.3 1.7 0.18 11.0 0.2 2.8 2 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KNE00853.1 - 0.0005 20.2 2.4 0.25 11.6 0.1 3.3 2 2 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KNE00853.1 - 0.00055 19.8 0.2 3.5 7.9 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KNE00853.1 - 0.00056 20.1 1.2 0.044 14.1 0.0 3.7 3 2 0 4 4 4 1 Tetratricopeptide repeat AChE_tetra PF08674.10 KNE00853.1 - 0.094 12.4 5.1 3.2 7.5 0.1 3.8 4 0 0 4 4 4 0 Acetylcholinesterase tetramerisation domain CCP_MauG PF03150.14 KNE00853.1 - 1.4 9.6 13.5 4.5 7.9 11.6 2.5 2 1 0 2 2 1 0 Di-haem cytochrome c peroxidase Ring_hydroxyl_A PF00848.19 KNE00854.1 - 2.9e-26 92.8 0.1 5e-26 92.0 0.1 1.3 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KNE00854.1 - 2.1e-16 59.6 0.1 6e-16 58.2 0.0 1.8 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain PIH1 PF08190.12 KNE00854.1 - 0.076 12.5 0.2 0.92 8.9 0.1 2.2 2 0 0 2 2 2 0 PIH1 N-terminal domain ARID PF01388.21 KNE00855.1 - 9.7e-12 45.4 0.1 3.4e-11 43.7 0.1 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Glyco_transf_34 PF05637.12 KNE00856.1 - 5e-67 226.1 0.1 6.1e-67 225.8 0.1 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Pex2_Pex12 PF04757.14 KNE00857.1 - 8.2e-35 120.4 2.6 1.1e-34 120.0 2.6 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 KNE00857.1 - 4.5e-09 36.5 14.6 7.6e-09 35.8 14.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KNE00857.1 - 1.5e-07 31.2 14.0 2.1e-07 30.7 14.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KNE00857.1 - 1.4e-06 28.1 12.8 2.3e-06 27.3 12.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KNE00857.1 - 3.1e-06 26.9 14.6 5.3e-06 26.2 14.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KNE00857.1 - 8.9e-06 25.6 6.4 8.9e-06 25.6 6.4 1.7 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KNE00857.1 - 0.00012 21.8 14.2 0.00019 21.2 14.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KNE00857.1 - 0.00019 21.3 9.9 0.00032 20.6 9.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KNE00857.1 - 0.00032 20.9 13.5 0.0007 19.8 13.5 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KNE00857.1 - 0.0016 18.5 13.0 0.003 17.7 13.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING CdiI PF07262.11 KNE00857.1 - 0.077 12.8 0.2 0.17 11.7 0.2 1.6 1 0 0 1 1 1 0 CDI immunity protein zf-RING_10 PF16685.5 KNE00857.1 - 0.21 11.7 11.4 0.44 10.7 11.4 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 KNE00857.1 - 1 9.5 8.1 1.6 8.8 8.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KNE00857.1 - 3 7.7 7.3 9.6 6.1 7.3 1.9 1 0 0 1 1 1 0 RING-like zinc finger IBR PF01485.21 KNE00857.1 - 7.3 6.9 11.0 20 5.5 11.1 1.6 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain IMS PF00817.20 KNE00858.1 - 4.1e-36 124.2 0.0 7.1e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 KNE00858.1 - 0.00011 21.7 0.1 0.00027 20.4 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Ferric_reduct PF01794.19 KNE00859.1 - 2.4e-13 50.3 14.0 2.4e-13 50.3 14.0 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KNE00859.1 - 1.2e-09 38.5 0.0 2.4e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KNE00859.1 - 1.1e-08 35.1 0.0 2.1e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Curto_V2 PF07325.11 KNE00859.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 0 Curtovirus V2 protein NAD_binding_1 PF00175.21 KNE00859.1 - 0.16 12.6 0.0 12 6.6 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF1461 PF07314.11 KNE00859.1 - 4.1 7.3 8.7 0.17 11.8 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) Imm75 PF15660.6 KNE00860.1 - 0.096 13.0 0.0 0.096 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative Immunity protein 75 CbiQ PF02361.16 KNE00862.1 - 6.2 6.4 17.8 8.3 6.0 17.8 1.2 1 0 0 1 1 1 0 Cobalt transport protein MotB_plug PF13677.6 KNE00863.1 - 0.44 10.2 2.9 0.55 9.9 2.9 1.2 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Ada_Zn_binding PF02805.16 KNE00865.1 - 2.4e-16 59.5 4.9 4.4e-16 58.6 4.9 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 KNE00865.1 - 3.4e-05 23.8 0.0 0.00011 22.1 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 KNE00865.1 - 0.00011 22.4 0.1 0.00036 20.8 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain Pkinase PF00069.25 KNE00868.1 - 1.9e-71 240.5 0.0 3e-71 239.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE00868.1 - 3e-38 131.6 0.0 4.5e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNE00868.1 - 6.5e-11 42.1 0.0 1.3e-07 31.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KNE00868.1 - 6.1e-07 28.6 1.1 1.3e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KNE00868.1 - 0.019 14.5 0.0 0.051 13.1 0.0 1.7 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.14 KNE00868.1 - 0.023 14.0 0.1 0.045 13.1 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nif11 PF07862.11 KNE00868.1 - 0.36 11.2 4.8 1.7 9.0 0.0 3.8 5 0 0 5 5 5 0 Nif11 domain Aminotran_3 PF00202.21 KNE00871.1 - 4.3e-110 368.2 0.0 4.9e-110 368.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KNE00871.1 - 0.0015 17.8 0.0 0.0024 17.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II SpoVAE PF14097.6 KNE00872.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.0 1 0 0 1 1 1 0 Stage V sporulation protein AE1 Longin_2 PF18639.1 KNE00873.1 - 1.5e-08 34.7 0.1 0.012 15.5 0.1 3.0 3 0 0 3 3 3 2 Yeast longin domain FNIP_N PF14636.6 KNE00873.1 - 0.0022 19.0 0.1 0.0022 19.0 0.1 3.8 2 2 1 3 3 3 1 Folliculin-interacting protein N-terminus SRI PF08236.11 KNE00875.1 - 5.2e-25 87.4 2.0 5.2e-25 87.4 2.0 2.7 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 KNE00875.1 - 2.7e-18 67.0 0.1 2.7e-18 67.0 0.1 3.4 2 2 1 3 3 3 1 SET domain AWS PF17907.1 KNE00875.1 - 1.3e-13 50.7 10.2 1.3e-13 50.7 10.2 2.0 2 0 0 2 2 2 1 AWS domain WW PF00397.26 KNE00875.1 - 7.9e-10 38.7 0.8 1.8e-09 37.5 0.8 1.6 1 0 0 1 1 1 1 WW domain Med26 PF08711.11 KNE00875.1 - 5.5e-05 23.1 1.6 0.00022 21.2 1.6 2.1 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF2116 PF09889.9 KNE00875.1 - 3.2 7.8 8.8 2.4 8.2 5.3 2.7 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) AP1AR PF15745.5 KNE00875.1 - 9.2 5.8 13.4 22 4.5 13.4 1.6 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein NAD_Gly3P_dh_N PF01210.23 KNE00876.1 - 8.1e-51 172.1 0.0 1.3e-50 171.5 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KNE00876.1 - 1e-41 142.5 0.3 1.8e-41 141.8 0.3 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 KNE00876.1 - 0.0064 17.0 0.0 2.6 8.7 0.0 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent DNA_ligase_A_N PF04675.14 KNE00876.1 - 0.18 12.1 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 DNA ligase N terminus zf-C2H2 PF00096.26 KNE00878.1 - 4.7e-10 39.4 5.2 0.00031 21.1 2.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KNE00878.1 - 7.5e-06 26.3 3.1 0.11 13.4 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KNE00878.1 - 0.033 14.6 0.3 3 8.3 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-LYAR PF08790.11 KNE00878.1 - 0.045 13.7 0.5 3.4 7.7 0.0 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-CHY PF05495.12 KNE00878.1 - 0.15 12.6 1.4 0.29 11.7 1.4 1.4 1 0 0 1 1 1 0 CHY zinc finger zf-C2H2_jaz PF12171.8 KNE00878.1 - 0.18 12.2 0.7 22 5.5 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KNE00878.1 - 0.19 11.5 1.3 0.43 10.4 0.0 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type ING PF12998.7 KNE00880.1 - 2.6e-24 85.7 0.1 4.7e-24 84.9 0.1 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KNE00880.1 - 3.6e-05 23.6 7.5 6e-05 22.8 7.5 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KNE00880.1 - 0.019 14.5 1.7 0.032 13.8 1.7 1.4 1 0 0 1 1 1 0 PHD-finger Ras PF00071.22 KNE00881.1 - 1.1e-57 194.2 0.1 1.3e-57 193.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNE00881.1 - 1.9e-21 76.5 0.0 2.7e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNE00881.1 - 8e-10 38.4 0.0 9.6e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KNE00881.1 - 5.4e-05 22.8 0.2 0.00023 20.7 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KNE00881.1 - 7.6e-05 22.8 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNE00881.1 - 0.00015 21.7 1.4 0.37 10.7 0.0 2.6 1 1 2 3 3 3 2 RsgA GTPase FeoB_N PF02421.18 KNE00881.1 - 0.0013 18.2 0.9 0.015 14.8 0.9 2.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 KNE00881.1 - 0.0015 17.9 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF2075 PF09848.9 KNE00881.1 - 0.033 13.4 0.2 2.1 7.5 0.0 2.0 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Septin PF00735.18 KNE00881.1 - 0.053 12.8 0.1 0.19 11.0 0.0 1.8 2 1 1 3 3 3 0 Septin ATP_bind_1 PF03029.17 KNE00881.1 - 0.48 10.2 2.1 4.2 7.1 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DAD PF02109.16 KNE00882.1 - 1.3e-42 144.5 4.5 1.8e-42 144.1 4.5 1.2 1 0 0 1 1 1 1 DAD family SWIB PF02201.18 KNE00883.1 - 0.038 13.9 0.1 0.05 13.5 0.1 1.2 1 0 0 1 1 1 0 SWIB/MDM2 domain Y_phosphatase2 PF03162.13 KNE00884.1 - 8.1e-49 165.4 0.0 9.8e-49 165.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KNE00884.1 - 6.2e-06 26.4 0.0 1.2e-05 25.4 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KNE00884.1 - 0.011 15.6 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain CRA PF06589.11 KNE00885.1 - 0.029 14.5 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) DUF5305 PF17231.2 KNE00885.1 - 0.11 11.9 2.9 0.12 11.8 0.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5305) KCT2 PF17818.1 KNE00885.1 - 0.15 12.2 2.9 0.23 11.6 2.9 1.2 1 0 0 1 1 1 0 Keratinocyte-associated gene product GSHPx PF00255.19 KNE00886.1 - 1.4e-46 156.5 0.1 1.8e-46 156.1 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KNE00886.1 - 2.2e-07 30.8 0.1 5.3e-06 26.4 0.1 2.1 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KNE00886.1 - 3.4e-06 26.8 0.0 1.6e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 Redoxin Xrn1_D3 PF18194.1 KNE00886.1 - 0.079 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Exoribonuclease 1 Domain-3 DUF3116 PF11313.8 KNE00887.1 - 0.024 14.5 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3116) Pkinase PF00069.25 KNE00888.1 - 1.1e-47 162.7 0.0 1.4e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE00888.1 - 2.5e-31 108.9 0.0 6.9e-31 107.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KNE00888.1 - 7.1e-05 22.8 0.0 0.0036 17.2 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KNE00888.1 - 0.01 15.1 0.0 0.13 11.5 0.0 2.1 1 1 0 2 2 2 0 Kinase-like CENP-B_dimeris PF09026.10 KNE00888.1 - 0.14 12.6 2.4 0.16 12.4 1.1 1.8 1 1 0 1 1 1 0 Centromere protein B dimerisation domain IlvN PF07991.12 KNE00889.1 - 8.6e-44 149.0 0.0 1.3e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KNE00889.1 - 1.5e-41 142.1 0.0 2.3e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TatD_DNase PF01026.21 KNE00889.1 - 0.22 10.9 0.0 0.5 9.7 0.0 1.6 1 0 0 1 1 1 0 TatD related DNase VASt PF16016.5 KNE00890.1 - 6.4e-32 111.1 0.1 1.3e-31 110.1 0.1 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KNE00890.1 - 1.5e-26 92.5 0.0 3.2e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 GRAM domain SspB PF04386.13 KNE00890.1 - 1.7 8.6 0.0 1.7 8.6 0.0 3.0 4 0 0 4 4 4 0 Stringent starvation protein B MMU163 PF17119.5 KNE00892.1 - 9.9e-20 70.7 0.0 1.3e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial protein up-regulated during meiosis HrpB1_HrpK PF09613.10 KNE00892.1 - 0.16 11.6 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) AhpC-TSA PF00578.21 KNE00893.1 - 2.1e-34 118.1 0.0 2.7e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KNE00893.1 - 5e-15 55.5 0.0 6.1e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KNE00893.1 - 1.9e-12 46.8 0.1 3.1e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DHHC PF01529.20 KNE00895.1 - 3.6e-34 117.7 5.0 6.2e-34 117.0 5.0 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Baculo_11_kDa PF06143.11 KNE00895.1 - 0.15 11.6 1.2 0.35 10.5 1.2 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family Proteasome PF00227.26 KNE00896.1 - 3e-53 180.1 0.0 3.6e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Cytochrom_B562 PF07361.11 KNE00897.1 - 0.0064 17.1 3.9 0.0064 17.1 3.9 5.5 3 1 2 5 5 5 1 Cytochrome b562 SNCAIP_SNCA_bd PF16700.5 KNE00897.1 - 2.1 8.1 13.3 0.71 9.6 1.9 3.5 3 0 0 3 3 3 0 Synphilin-1 alpha-Synuclein-binding domain ATG16 PF08614.11 KNE00897.1 - 2.3 8.4 66.8 0.55 10.4 3.4 4.9 5 0 0 5 5 5 0 Autophagy protein 16 (ATG16) eIF2A PF08662.11 KNE00898.1 - 2.7e-38 131.8 1.3 2.9e-34 118.6 1.2 2.9 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KNE00898.1 - 1.2e-05 25.0 0.0 3.2e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC4_WD40 PF12894.7 KNE00898.1 - 0.025 14.9 0.1 14 6.1 0.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain AAA_23 PF13476.6 KNE00898.1 - 6.3 7.3 8.3 12 6.3 7.4 1.9 1 1 0 1 1 1 0 AAA domain BolA PF01722.18 KNE00899.1 - 7.4e-14 51.8 0.0 2.3e-13 50.2 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein EF_assoc_1 PF08355.12 KNE00900.1 - 1.9e-29 101.0 0.3 4.4e-29 99.9 0.3 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_2 PF08356.12 KNE00900.1 - 5.8e-26 90.3 0.0 1.2e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KNE00900.1 - 6.5e-24 84.4 0.0 4.6e-12 45.8 0.0 3.2 2 1 0 2 2 2 2 Ras family Roc PF08477.13 KNE00900.1 - 1.2e-12 48.2 0.0 0.00016 21.9 0.0 3.5 3 0 0 3 3 3 3 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 KNE00900.1 - 5.7e-10 38.0 4.9 0.0002 20.7 0.1 3.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KNE00900.1 - 9e-09 35.7 1.2 4.3e-05 23.9 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KNE00900.1 - 3.4e-08 32.8 3.9 0.0037 17.1 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KNE00900.1 - 3.5e-07 29.4 3.1 0.0086 15.5 2.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KNE00900.1 - 2.3e-05 24.1 2.1 0.047 13.5 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair Arf PF00025.21 KNE00900.1 - 2.4e-05 23.9 0.0 0.37 10.2 0.0 3.5 3 1 0 3 3 3 2 ADP-ribosylation factor family AAA_14 PF13173.6 KNE00900.1 - 0.0023 17.9 0.1 0.44 10.6 0.2 3.2 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KNE00900.1 - 0.0046 17.0 0.0 5.4 7.1 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KNE00900.1 - 0.022 14.3 0.0 4.9 6.6 0.0 2.8 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KNE00900.1 - 0.039 14.0 0.0 1.6 8.8 0.0 2.6 2 1 0 2 2 2 0 Dynamin family SRPRB PF09439.10 KNE00900.1 - 0.077 12.4 0.0 0.59 9.6 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Cyclase_polyket PF04673.12 KNE00900.1 - 0.1 12.9 0.0 2.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Polyketide synthesis cyclase EF-hand_4 PF12763.7 KNE00900.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand TniB PF05621.11 KNE00900.1 - 0.15 11.4 0.0 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein SPARC_Ca_bdg PF10591.9 KNE00900.1 - 0.32 11.3 1.0 22 5.4 0.0 3.1 3 0 0 3 3 2 0 Secreted protein acidic and rich in cysteine Ca binding region RRS1 PF04939.12 KNE00901.1 - 5e-60 202.0 6.4 5.9e-60 201.8 6.4 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Acetyltransf_4 PF13420.7 KNE00903.1 - 0.054 13.6 0.0 0.06 13.5 0.0 1.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SWIB PF02201.18 KNE00904.1 - 5.3e-29 99.9 1.1 9.6e-29 99.1 1.1 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DUF4611 PF15387.6 KNE00904.1 - 2.6 8.3 11.2 0.053 13.7 4.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) S-antigen PF05756.11 KNE00904.1 - 6.1 7.3 8.3 1.8 9.0 3.0 2.3 2 0 0 2 2 2 0 S-antigen protein Membr_traf_MHD PF10540.9 KNE00905.1 - 2.1e-39 135.1 1.2 2.1e-39 135.1 1.2 2.1 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KNE00905.1 - 1.3e-08 35.0 0.0 5.6e-08 33.0 0.0 2.1 1 0 0 1 1 1 1 C2 domain TBCC_N PF16752.5 KNE00905.1 - 7.6 7.0 9.3 20 5.6 0.1 4.0 4 0 0 4 4 4 0 Tubulin-specific chaperone C N-terminal domain Sin3a_C PF16879.5 KNE00906.1 - 8.1e-82 275.2 4.5 8.1e-82 275.2 4.5 4.3 5 0 0 5 5 5 1 C-terminal domain of Sin3a protein PAH PF02671.21 KNE00906.1 - 1e-46 156.8 10.1 1.9e-18 66.3 1.3 4.1 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KNE00906.1 - 7.2e-42 141.4 0.1 2.1e-41 140.0 0.1 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor Pkinase PF00069.25 KNE00907.1 - 8e-72 241.8 0.3 1.6e-71 240.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE00907.1 - 3.2e-36 125.0 0.0 6.2e-36 124.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KNE00907.1 - 9.7e-23 80.1 2.8 2.6e-11 43.5 0.0 3.1 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.6 KNE00907.1 - 2e-10 40.4 0.0 4.2e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KNE00907.1 - 0.0084 15.5 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KNE00907.1 - 0.045 13.7 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4205 PF13898.6 KNE00907.1 - 0.18 10.7 1.9 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4205) RNase_H PF00075.24 KNE00908.1 - 1.1e-30 106.7 1.4 2.4e-30 105.6 1.4 1.6 1 1 0 1 1 1 1 RNase H Cauli_VI PF01693.16 KNE00908.1 - 1.5e-16 60.4 1.1 1.5e-16 60.4 1.1 1.8 2 0 0 2 2 2 1 Caulimovirus viroplasmin Spem1 PF15670.5 KNE00909.1 - 0.12 11.9 3.2 2.7 7.5 1.0 2.2 2 0 0 2 2 2 0 Spermatid maturation protein 1 NB PF04159.13 KNE00910.1 - 0.057 13.5 0.2 0.071 13.1 0.2 1.1 1 0 0 1 1 1 0 NB glycoprotein Topoisom_I_N PF02919.15 KNE00911.1 - 1.2e-97 325.6 0.1 1.2e-97 325.6 0.1 3.5 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 KNE00911.1 - 2e-96 321.7 5.2 2e-96 321.7 5.2 2.3 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 KNE00911.1 - 1.4e-30 105.0 0.9 1.4e-30 105.0 0.9 2.7 2 0 0 2 2 2 1 C-terminal topoisomerase domain Connexin PF00029.19 KNE00912.1 - 0.004 16.9 0.0 0.0058 16.4 0.0 1.2 1 0 0 1 1 1 1 Connexin TMEM154 PF15102.6 KNE00912.1 - 0.0053 16.7 6.9 1.5 8.7 0.0 2.2 1 1 1 2 2 2 2 TMEM154 protein family DUF4271 PF14093.6 KNE00912.1 - 0.0084 16.0 0.2 0.013 15.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) DUF2207 PF09972.9 KNE00912.1 - 0.01 14.6 1.1 0.15 10.7 1.1 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Insulin_TMD PF17870.1 KNE00912.1 - 0.021 14.9 0.3 0.043 13.9 0.3 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4389 PF14333.6 KNE00912.1 - 0.03 14.3 1.4 0.055 13.4 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) NPR3 PF03666.13 KNE00912.1 - 0.032 13.0 1.7 0.046 12.5 1.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Orf78 PF06024.12 KNE00912.1 - 0.037 14.3 3.9 1 9.7 0.1 2.6 1 1 0 2 2 2 0 Orf78 (ac78) Cu_amine_oxid PF01179.20 KNE00912.1 - 0.065 12.1 0.4 0.088 11.7 0.4 1.1 1 0 0 1 1 1 0 Copper amine oxidase, enzyme domain SAPS PF04499.15 KNE00912.1 - 0.068 11.9 1.7 0.084 11.6 1.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein stn_TNFRSF12A PF12191.8 KNE00912.1 - 0.074 13.3 0.3 4.9 7.4 0.2 2.5 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Gemini_mov PF01708.16 KNE00912.1 - 0.13 12.0 0.2 0.33 10.7 0.2 1.6 1 0 0 1 1 1 0 Geminivirus putative movement protein Tim54 PF11711.8 KNE00912.1 - 0.17 10.6 3.1 0.23 10.2 3.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Adeno_E3_CR2 PF02439.15 KNE00912.1 - 0.2 11.4 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PPL5 PF18168.1 KNE00912.1 - 0.48 9.7 4.0 0.67 9.2 4.0 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Mucin PF01456.17 KNE00912.1 - 0.73 9.8 16.5 1.3 9.1 16.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF4381 PF14316.6 KNE00912.1 - 0.92 9.7 2.5 2 8.6 2.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) FAM176 PF14851.6 KNE00912.1 - 1.2 8.8 4.7 6.3 6.4 2.6 2.4 2 0 0 2 2 2 0 FAM176 family RNA_pol_Rpc4 PF05132.14 KNE00912.1 - 1.2 9.6 9.2 2 8.8 9.2 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 CPSF100_C PF13299.6 KNE00912.1 - 1.2 9.3 6.5 2 8.6 6.5 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4834 PF16118.5 KNE00912.1 - 2.9 8.9 6.2 27 5.8 3.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Podoplanin PF05808.11 KNE00912.1 - 7 6.7 12.6 15 5.6 12.6 1.5 1 1 0 1 1 1 0 Podoplanin Sec-ASP3 PF15432.6 KNE00913.1 - 0.059 13.5 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Accessory Sec secretory system ASP3 DUF2076 PF09849.9 KNE00915.1 - 1.7e-06 28.3 4.1 1.8e-06 28.2 4.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 KNE00915.1 - 0.00064 19.8 3.9 0.0013 18.9 3.9 1.5 1 0 0 1 1 1 1 CHCH domain Trypan_glycop_C PF10659.9 KNE00915.1 - 0.073 13.4 2.5 0.11 12.9 2.5 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain Nucleoporin_FG PF13634.6 KNE00915.1 - 0.08 13.8 10.5 0.12 13.2 10.5 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeat region Na_K-ATPase PF00287.18 KNE00915.1 - 0.68 9.1 5.7 1.3 8.1 5.7 1.4 1 1 0 1 1 1 0 Sodium / potassium ATPase beta chain DnaJ PF00226.31 KNE00917.1 - 3.9e-15 55.7 5.6 7.2e-15 54.9 5.6 1.5 1 0 0 1 1 1 1 DnaJ domain Enkurin PF13864.6 KNE00917.1 - 0.03 14.7 0.8 0.072 13.5 0.8 1.6 1 0 0 1 1 1 0 Calmodulin-binding DUF1296 PF06972.11 KNE00917.1 - 0.11 12.6 0.2 0.21 11.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Complex1_49kDa PF00346.19 KNE00919.1 - 7.6e-122 405.6 0.0 9.5e-122 405.3 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KNE00919.1 - 0.013 14.4 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase Helicase_C PF00271.31 KNE00920.1 - 2.1e-15 57.0 0.0 8.2e-15 55.1 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KNE00920.1 - 4e-12 46.3 0.0 1.9e-11 44.2 0.0 2.2 1 1 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KNE00920.1 - 1.2e-11 44.9 2.6 1.5e-11 44.5 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 KNE00920.1 - 2.9e-08 33.7 0.4 5.7e-08 32.7 0.4 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RWD PF05773.22 KNE00920.1 - 2.6e-07 30.9 2.3 2.7e-07 30.9 0.3 2.2 2 0 0 2 2 2 1 RWD domain AAA_29 PF13555.6 KNE00920.1 - 0.0013 18.5 0.0 0.0033 17.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KNE00920.1 - 0.011 16.0 0.3 0.081 13.2 0.3 2.4 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KNE00920.1 - 0.012 16.0 0.0 0.039 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KNE00920.1 - 0.015 14.7 0.1 0.035 13.5 0.1 1.6 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 KNE00920.1 - 0.026 14.6 2.4 1.6 8.8 0.6 3.6 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 KNE00920.1 - 0.041 12.9 0.0 0.084 11.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein UBA_2 PF08587.11 KNE00920.1 - 0.049 13.7 0.1 0.18 12.0 0.1 2.0 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) AAA_7 PF12775.7 KNE00920.1 - 0.05 13.1 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region dsRBD2 PF17842.1 KNE00920.1 - 0.095 12.9 1.3 0.16 12.1 0.0 2.0 2 0 0 2 2 1 0 Double-stranded RNA binding domain 2 PhoH PF02562.16 KNE00920.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein HNF-1_N PF04814.13 KNE00920.1 - 0.47 11.1 0.0 0.47 11.1 0.0 2.8 4 0 0 4 4 3 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus OPT PF03169.15 KNE00922.1 - 5.9e-124 415.0 44.9 6.9e-124 414.7 44.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Sm_multidrug_ex PF06695.11 KNE00922.1 - 0.0072 17.0 2.0 0.56 10.9 0.2 3.0 2 0 0 2 2 2 2 Putative small multi-drug export protein TFIID_20kDa PF03847.13 KNE00923.1 - 1.6e-29 102.2 0.1 2.7e-29 101.5 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.15 KNE00923.1 - 0.0023 18.0 0.0 0.0054 16.8 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DUF2156 PF09924.9 KNE00923.1 - 0.0084 15.1 0.7 0.014 14.4 0.7 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) CBFD_NFYB_HMF PF00808.23 KNE00923.1 - 0.034 14.4 0.0 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone V-SNARE PF05008.15 KNE00923.1 - 0.047 14.1 0.6 0.047 14.1 0.6 2.7 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus MtrG PF04210.13 KNE00923.1 - 0.085 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G Osmo_CC PF08946.10 KNE00923.1 - 0.17 12.1 0.5 0.42 10.9 0.5 1.6 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Med15_fungi PF05397.12 KNE00923.1 - 1.4 9.2 6.5 0.7 10.2 1.3 2.6 2 1 1 3 3 3 0 Mediator complex subunit 15 Cullin PF00888.22 KNE00924.1 - 3.2e-12 45.9 2.8 4.3e-12 45.5 0.0 2.3 3 0 0 3 3 3 1 Cullin family Cullin_binding PF03556.15 KNE00925.1 - 7.6e-29 100.6 3.9 9.9e-29 100.2 3.9 1.2 1 0 0 1 1 1 1 Cullin binding HLH PF00010.26 KNE00926.1 - 5.8e-11 42.2 0.0 1.9e-10 40.5 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain AATase PF07247.12 KNE00927.1 - 5.4e-45 153.9 0.0 1.7e-44 152.2 0.0 1.7 1 1 0 1 1 1 1 Alcohol acetyltransferase NAD_binding_6 PF08030.12 KNE00927.1 - 0.11 12.6 0.0 11 6.2 0.0 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain TetR_C_13 PF16925.5 KNE00928.1 - 0.12 12.3 0.0 0.13 12.2 0.0 1.0 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Zn_clus PF00172.18 KNE00931.1 - 4.1e-08 33.2 8.7 9.4e-08 32.1 8.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KH_6 PF15985.5 KNE00934.1 - 2.5e-15 56.6 0.2 4.6e-15 55.7 0.2 1.4 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 KNE00934.1 - 3e-11 43.1 0.0 5.4e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain tRNA_anti-codon PF01336.25 KNE00934.1 - 0.05 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain LCM PF04072.14 KNE00935.1 - 4.3e-21 75.7 0.0 8e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 KNE00935.1 - 1.2e-14 54.0 2.2 4.1e-09 36.3 0.2 5.1 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_3 PF13415.6 KNE00935.1 - 1.3e-08 34.9 1.1 0.0042 17.4 0.2 4.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KNE00935.1 - 1.8e-07 30.8 5.2 1.2e-06 28.3 0.6 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.6 KNE00935.1 - 1.4e-06 28.4 8.2 1.8e-06 28.0 0.1 4.3 4 1 1 5 5 5 1 Kelch motif Kelch_1 PF01344.25 KNE00935.1 - 0.00064 19.3 0.7 0.00064 19.3 0.7 5.2 7 0 0 7 7 7 2 Kelch motif Kelch_5 PF13854.6 KNE00935.1 - 0.0034 17.3 2.0 1.8 8.6 0.1 4.1 4 0 0 4 4 4 1 Kelch motif CBM_21 PF03370.13 KNE00938.1 - 2.1e-36 124.5 0.0 3.8e-36 123.7 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KNE00938.1 - 1.3e-07 32.0 0.0 7.7e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) NAPRTase PF04095.16 KNE00938.1 - 0.014 15.1 0.0 0.033 13.8 0.0 1.6 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) family WD40 PF00400.32 KNE00939.1 - 7e-44 146.9 19.8 5.2e-07 30.3 0.8 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.8 KNE00939.1 - 2.3e-14 52.9 6.4 0.0013 17.5 0.2 5.5 3 1 3 6 6 6 4 Nucleoporin Nup120/160 F-box-like PF12937.7 KNE00939.1 - 8.2e-14 51.2 0.7 1.7e-13 50.2 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KNE00939.1 - 6.1e-11 41.9 0.6 1.5e-10 40.6 0.6 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KNE00939.1 - 2.5e-08 34.1 2.1 0.086 13.2 0.0 5.5 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KNE00939.1 - 5.6e-06 26.4 0.0 0.098 12.7 0.0 3.8 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 KNE00939.1 - 1.4e-05 24.6 0.3 0.00048 19.5 0.1 2.1 2 0 0 2 2 2 1 WD40-like domain eIF2A PF08662.11 KNE00939.1 - 0.00056 19.8 1.5 0.75 9.6 0.1 2.8 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A F-box_4 PF15966.5 KNE00939.1 - 0.0024 17.7 0.0 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 F-box PRANC PF09372.10 KNE00939.1 - 0.03 14.7 0.1 0.064 13.6 0.1 1.6 1 0 0 1 1 1 0 PRANC domain CDC37_M PF08565.11 KNE00939.1 - 0.093 12.7 0.1 0.31 11.0 0.1 1.9 1 1 0 1 1 1 0 Cdc37 Hsp90 binding domain zf-ZPR1 PF03367.13 KNE00943.1 - 9.5e-117 386.3 2.4 1.2e-57 194.2 0.1 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain EzrA PF06160.12 KNE00943.1 - 0.018 13.2 0.8 0.034 12.3 0.8 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Cytochrom_C_2 PF01322.20 KNE00943.1 - 0.033 15.1 6.7 0.42 11.5 0.6 3.9 4 0 0 4 4 4 0 Cytochrome C' zinc-ribbons_6 PF07191.12 KNE00943.1 - 0.26 11.3 4.6 1.7 8.7 0.5 2.6 2 0 0 2 2 2 0 zinc-ribbons zf-RRPl_C4 PF17026.5 KNE00943.1 - 1.9 8.6 6.8 8.5 6.5 1.0 2.9 3 0 0 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type Ion_trans PF00520.31 KNE00944.1 - 2.8e-124 413.2 105.7 8.3e-37 126.7 11.0 5.1 5 0 0 5 5 5 5 Ion transport protein GPHH PF16905.5 KNE00944.1 - 0.00068 19.4 0.0 0.0019 17.9 0.0 1.8 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_7 PF13499.6 KNE00944.1 - 0.0015 18.9 0.0 0.0047 17.4 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KNE00944.1 - 0.034 14.1 0.0 0.14 12.2 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 KNE00944.1 - 0.056 13.0 0.0 0.28 10.8 0.0 2.3 2 0 0 2 2 2 0 EF hand CysG_dimeriser PF10414.9 KNE00944.1 - 0.25 11.1 0.5 0.64 9.8 0.0 1.9 2 0 0 2 2 2 0 Sirohaem synthase dimerisation region MRP-S33 PF08293.11 KNE00946.1 - 2.3e-28 98.2 0.1 2.7e-28 98.0 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 DCP1 PF06058.13 KNE00947.1 - 0.021 14.7 0.0 0.067 13.1 0.0 1.9 1 0 0 1 1 1 0 Dcp1-like decapping family YfhO PF09586.10 KNE00948.1 - 0.021 13.1 1.1 0.021 13.1 1.1 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO MIS13 PF08202.11 KNE00949.1 - 2.3e-43 148.6 0.3 4e-43 147.8 0.3 1.3 1 0 0 1 1 1 1 Mis12-Mtw1 protein family PBP1_TM PF14812.6 KNE00949.1 - 0.56 10.6 6.2 6.6 7.2 3.5 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_hydro_65m PF03632.15 KNE00950.1 - 2.9e-33 115.3 3.3 3.6e-30 105.1 1.4 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 KNE00950.1 - 1.6e-25 90.1 0.0 4.3e-25 88.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain F5_F8_type_C PF00754.25 KNE00950.1 - 0.032 14.3 0.1 0.12 12.5 0.1 2.0 1 0 0 1 1 1 0 F5/8 type C domain Mucin_bdg PF03272.13 KNE00950.1 - 0.1 12.6 0.0 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 Putative mucin or carbohydrate-binding module WD40 PF00400.32 KNE00951.1 - 5.9e-11 42.7 3.6 0.0052 17.6 0.1 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat SRA1 PF07304.11 KNE00951.1 - 2.3e-10 40.5 0.0 2.3e-10 40.5 0.0 4.6 7 0 0 7 7 7 1 Steroid receptor RNA activator (SRA1) DUF1204 PF06721.11 KNE00951.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) Ribonuc_L-PSP PF01042.21 KNE00954.1 - 4.6e-11 42.8 0.0 4.8e-11 42.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Eclosion PF04736.12 KNE00954.1 - 0.017 14.8 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Eclosion hormone AIM24 PF01987.17 KNE00957.1 - 0.0012 18.7 0.0 0.0013 18.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 RTA1 PF04479.13 KNE00958.1 - 8.7e-68 228.0 11.1 1.5e-67 227.3 11.1 1.3 1 0 0 1 1 1 1 RTA1 like protein PDR_CDR PF06422.12 KNE00958.1 - 0.31 11.0 1.7 0.84 9.6 0.3 2.3 2 0 0 2 2 2 0 CDR ABC transporter DUF202 PF02656.15 KNE00958.1 - 0.74 10.3 3.2 2.1 8.8 0.7 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Flavi_NS2B PF01002.19 KNE00959.1 - 0.056 13.3 0.1 0.064 13.1 0.1 1.1 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B RTA1 PF04479.13 KNE00960.1 - 3.1e-67 226.2 9.1 3.1e-67 226.2 9.1 1.5 2 0 0 2 2 2 1 RTA1 like protein Cyclin PF08613.11 KNE00961.1 - 3.6e-41 141.2 0.4 1e-40 139.7 0.4 1.7 1 1 0 1 1 1 1 Cyclin PET117 PF15786.5 KNE00962.1 - 9.8e-24 83.4 1.2 1.1e-23 83.2 1.2 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial DUF4748 PF15932.5 KNE00962.1 - 0.46 10.3 2.8 4.1 7.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4748) zf-H2C2_2 PF13465.6 KNE00963.1 - 0.039 14.4 1.5 4.3 7.9 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 KNE00963.1 - 0.043 14.3 0.3 0.12 12.8 0.3 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KNE00963.1 - 0.068 13.5 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KNE00963.1 - 0.15 13.0 0.5 0.48 11.4 0.5 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger EB1 PF03271.17 KNE00965.1 - 3e-12 46.6 0.5 7.2e-12 45.4 0.5 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 KNE00965.1 - 7.4e-08 32.6 0.4 1.4e-07 31.7 0.4 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain FliD_N PF02465.18 KNE00965.1 - 0.099 13.3 1.0 0.33 11.7 0.0 2.3 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus UQ_con PF00179.26 KNE00966.1 - 4.8e-39 133.2 0.4 7.6e-39 132.6 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IATP PF04568.12 KNE00968.1 - 1.7e-10 41.2 4.4 1.7e-10 41.1 4.4 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP CASP_C PF08172.12 KNE00968.1 - 0.024 14.0 2.6 0.024 14.0 2.6 1.3 1 1 0 1 1 1 0 CASP C terminal Glutaredoxin2_C PF04399.13 KNE00968.1 - 0.043 13.6 1.3 0.046 13.6 1.3 1.0 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain U1snRNP70_N PF12220.8 KNE00968.1 - 0.3 11.8 5.3 0.33 11.6 5.3 1.1 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal FliD_N PF02465.18 KNE00968.1 - 0.32 11.7 2.6 0.43 11.3 2.6 1.3 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus XhlA PF10779.9 KNE00968.1 - 0.53 10.5 5.7 0.5 10.6 5.0 1.3 1 1 0 1 1 1 0 Haemolysin XhlA Ribosomal_S18 PF01084.20 KNE00970.1 - 1.9e-15 56.8 0.0 3.8e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 Metallophos PF00149.28 KNE00971.1 - 3.5e-37 128.9 0.2 4.7e-37 128.5 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KNE00971.1 - 0.023 15.1 0.8 0.055 13.9 0.8 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 KNE00971.1 - 0.053 13.1 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF5378 PF17349.2 KNE00971.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) RRM_1 PF00076.22 KNE00972.1 - 2.5e-52 174.6 0.2 1.5e-14 53.5 0.0 5.6 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KNE00972.1 - 1.8e-06 28.0 0.2 0.031 14.4 0.0 4.3 4 0 0 4 4 4 2 RNA recognition motif RRM_Rrp7 PF17799.1 KNE00972.1 - 0.0058 16.4 0.5 2.6 7.8 0.1 3.9 3 1 1 4 4 4 2 Rrp7 RRM-like N-terminal domain CENP-N PF05238.13 KNE00973.1 - 6.1e-99 332.1 0.2 7.5e-99 331.9 0.2 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like Vps16_N PF04841.13 KNE00974.1 - 4e-47 160.9 3.1 4.7e-45 154.1 0.1 3.6 2 1 0 2 2 2 1 Vps16, N-terminal region Vps16_C PF04840.12 KNE00974.1 - 1.2e-33 116.5 14.0 4.4e-23 81.8 5.5 2.4 1 1 1 2 2 2 2 Vps16, C-terminal region YedD PF13987.6 KNE00974.1 - 0.011 15.5 0.1 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 YedD-like protein MmlI PF09448.10 KNE00974.1 - 0.091 13.2 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase Skp1_POZ PF03931.15 KNE00975.1 - 1.3e-06 28.5 0.1 2e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain CLTH PF10607.9 KNE00976.1 - 4.1e-13 49.4 0.1 9.7e-13 48.2 0.1 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain AdoMet_MTase PF07757.13 KNE00978.1 - 2e-40 137.6 0.0 4.2e-40 136.6 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Pkinase PF00069.25 KNE00979.1 - 3.3e-59 200.4 0.0 3.7e-59 200.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE00979.1 - 4.1e-26 91.8 0.0 5.3e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DisA-linker PF10635.9 KNE00979.1 - 0.0061 16.3 0.1 0.0083 15.9 0.1 1.2 1 0 0 1 1 1 1 DisA bacterial checkpoint controller linker region Kinase-like PF14531.6 KNE00979.1 - 0.022 14.1 0.1 0.043 13.1 0.1 1.5 1 1 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KNE00979.1 - 0.043 12.7 0.0 0.063 12.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KNE00979.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KNE00979.1 - 0.065 12.3 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PBCV_basic_adap PF08789.10 KNE00980.1 - 0.092 12.9 0.2 0.17 12.1 0.2 1.4 1 0 0 1 1 1 0 PBCV-specific basic adaptor domain ICL PF00463.21 KNE00981.1 - 1.1e-303 1007.5 2.2 1.3e-303 1007.3 2.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KNE00981.1 - 1.3e-11 44.5 0.0 2.3e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF3197 PF11432.8 KNE00981.1 - 0.029 14.3 0.3 0.36 10.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3197) Humanin PF15040.6 KNE00983.1 - 0.33 10.4 0.1 0.33 10.4 0.1 1.8 2 0 0 2 2 2 0 Humanin family PQ-loop PF04193.14 KNE00984.1 - 3.1e-11 42.9 9.4 1.3e-07 31.2 2.7 3.9 5 1 0 5 5 5 2 PQ loop repeat ER_lumen_recept PF00810.18 KNE00984.1 - 0.072 13.9 13.6 0.21 12.4 9.6 2.8 1 1 0 1 1 1 0 ER lumen protein retaining receptor MtN3_slv PF03083.16 KNE00984.1 - 0.15 12.1 12.5 0.48 10.5 3.0 2.4 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange zf-C2H2 PF00096.26 KNE00986.1 - 4.6e-06 26.8 4.1 0.018 15.5 1.8 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type Cir_Bir_Yir PF06022.11 KNE00986.1 - 0.0053 16.3 0.5 0.0086 15.6 0.5 1.3 1 0 0 1 1 1 1 Plasmodium variant antigen protein Cir/Yir/Bir zf_ZIC PF18366.1 KNE00986.1 - 0.029 14.5 0.1 1.5 9.0 0.3 2.3 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-Di19 PF05605.12 KNE00986.1 - 0.057 13.7 0.1 0.13 12.6 0.1 1.6 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KNE00986.1 - 0.12 13.3 8.5 1.4 9.9 0.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger His_Phos_1 PF00300.22 KNE00987.1 - 6.8e-34 117.3 0.0 7.4e-24 84.5 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF5128 PF17170.4 KNE00989.1 - 0.1 11.7 0.0 0.12 11.4 0.0 1.0 1 0 0 1 1 1 0 6-bladed beta-propeller DUF3605 PF12239.8 KNE00990.1 - 1.5e-49 168.2 0.6 1.7e-49 168.0 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) CENP-T_C PF15511.6 KNE00991.1 - 9.1e-10 38.6 0.1 1.1e-09 38.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KNE00991.1 - 1.7e-05 24.9 0.1 2.4e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KNE00991.1 - 3.8e-05 23.9 0.1 6.5e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KNE00991.1 - 8.4e-05 22.9 0.1 9.8e-05 22.7 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KNE00991.1 - 8.8e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KNE00991.1 - 0.0026 17.8 0.0 0.0031 17.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KNE00991.1 - 0.0047 16.9 0.0 0.0056 16.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated UPF0137 PF03677.13 KNE00991.1 - 0.019 14.8 0.2 0.023 14.5 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TAFII28 PF04719.14 KNE00991.1 - 0.051 13.7 0.0 0.06 13.4 0.0 1.1 1 0 0 1 1 1 0 hTAFII28-like protein conserved region TFIID_20kDa PF03847.13 KNE00991.1 - 0.069 13.7 0.1 0.13 12.8 0.1 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.24 KNE00993.1 - 2.2e-51 173.6 2.4 2.5e-51 173.5 2.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KNE00993.1 - 3.8e-06 27.2 0.0 5.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 KNE00993.1 - 4.1e-05 24.2 1.1 4.9e-05 23.9 1.1 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 KNE00993.1 - 5e-05 23.4 0.5 7.9e-05 22.7 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KNE00993.1 - 0.0054 17.0 0.6 0.0079 16.5 0.1 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KNE00993.1 - 0.023 14.8 0.1 0.039 14.0 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit DUF3445 PF11927.8 KNE00994.1 - 1.7e-78 263.3 0.0 2.1e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Mannosyl_trans2 PF04188.13 KNE00995.1 - 2.4e-48 165.5 32.9 2.2e-43 149.2 20.1 2.0 1 1 1 2 2 2 2 Mannosyltransferase (PIG-V) AMP-binding PF00501.28 KNE00996.1 - 8.5e-89 298.1 0.0 1.2e-88 297.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KNE00996.1 - 8.6e-26 90.7 1.1 4.3e-25 88.5 0.2 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KNE00996.1 - 2.7e-19 68.8 0.2 1e-18 67.0 0.2 2.1 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus HSP70 PF00012.20 KNE00998.1 - 2.3e-261 868.3 7.9 2.6e-261 868.1 7.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KNE00998.1 - 1.3e-17 63.6 0.0 2e-16 59.8 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KNE00998.1 - 0.0023 17.7 0.0 0.0063 16.3 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 KNE00998.1 - 0.018 14.3 0.1 0.072 12.3 0.1 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase PMBR PF09373.10 KNE00998.1 - 0.48 10.7 0.0 0.48 10.7 0.0 2.8 4 0 0 4 4 4 0 Pseudomurein-binding repeat Ras PF00071.22 KNE00999.1 - 1.4e-42 145.0 0.0 1.7e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNE00999.1 - 2.6e-18 66.4 0.0 3.8e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNE00999.1 - 3.8e-06 26.5 0.0 5.3e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KNE00999.1 - 0.036 14.2 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 KNE00999.1 - 0.049 13.1 0.1 0.059 12.8 0.1 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KNE00999.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KNE00999.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KNE00999.1 - 0.11 12.3 0.1 0.26 11.0 0.1 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation UPF0121 PF03661.13 KNE01000.1 - 3.8e-30 105.0 8.2 4.9e-30 104.7 8.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Fumarate_red_C PF02300.17 KNE01000.1 - 8.2 6.5 9.6 0.82 9.8 0.2 2.7 2 1 1 3 3 3 0 Fumarate reductase subunit C Septin PF00735.18 KNE01001.1 - 2.8e-107 358.2 0.2 2.8e-107 358.2 0.2 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KNE01001.1 - 9.5e-05 22.4 0.8 0.00023 21.2 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNE01001.1 - 0.00018 21.5 3.2 0.017 15.0 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 KNE01001.1 - 0.0011 19.3 0.2 0.0054 17.0 0.2 2.4 1 1 0 1 1 1 1 AAA domain Strep_SA_rep PF06696.11 KNE01001.1 - 0.0032 17.4 2.1 0.0032 17.4 2.1 2.2 2 0 0 2 2 2 1 Streptococcal surface antigen repeat ABC_tran PF00005.27 KNE01001.1 - 0.0033 18.0 1.9 0.2 12.1 0.0 2.6 2 1 0 2 2 2 1 ABC transporter AAA_5 PF07728.14 KNE01001.1 - 0.0091 16.0 0.7 3.8 7.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KNE01001.1 - 0.011 16.1 0.2 0.046 14.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 KNE01001.1 - 0.014 15.8 0.1 0.65 10.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 KNE01001.1 - 0.031 14.5 0.0 0.085 13.1 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KNE01001.1 - 0.051 13.1 4.0 0.22 11.0 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 KNE01001.1 - 0.097 12.4 3.9 0.18 11.5 1.1 2.7 1 1 1 2 2 2 0 AAA domain Exonuc_VII_L PF02601.15 KNE01001.1 - 5.9 6.4 9.5 9.5 5.7 9.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CinA PF02464.17 KNE01002.1 - 2.7e-30 105.0 0.0 3.4e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Competence-damaged protein GP52 PF17468.2 KNE01002.1 - 0.025 14.7 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 Phage gene product 52 HlyD_D4 PF16572.5 KNE01002.1 - 0.033 14.1 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB Proteasom_Rpn13 PF04683.13 KNE01004.1 - 2.7e-23 82.3 0.0 3.5e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Pkinase PF00069.25 KNE01006.1 - 9.4e-51 172.7 0.0 4.9e-33 114.6 0.0 3.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNE01006.1 - 2.1e-23 82.9 0.0 4.8e-21 75.2 0.0 3.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNE01006.1 - 0.00014 21.3 0.0 0.018 14.4 0.0 2.3 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KNE01006.1 - 0.0012 17.7 0.0 0.0029 16.5 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase SpoVIF PF14069.6 KNE01006.1 - 0.12 12.2 0.0 0.36 10.7 0.0 1.8 1 0 0 1 1 1 0 Stage VI sporulation protein F DUF3899 PF13038.6 KNE01007.1 - 0.25 11.8 1.9 0.25 11.9 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) Ac76 PF05814.11 KNE01007.1 - 8.7 6.4 8.4 11 6.1 8.4 1.2 1 1 0 1 1 1 0 Orf76 (Ac76) DUF3543 PF12063.8 KNE01008.1 - 1.2e-84 283.6 3.7 2.1e-84 282.8 3.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 KNE01008.1 - 2.8e-63 213.7 0.0 5.9e-63 212.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE01008.1 - 2.8e-43 148.1 0.0 4.3e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNE01008.1 - 1.6e-07 30.9 0.1 0.048 13.0 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 KNE01008.1 - 0.052 12.3 0.0 0.11 11.2 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase FOP_dimer PF09398.10 KNE01008.1 - 0.098 12.9 0.1 0.32 11.3 0.1 1.8 1 0 0 1 1 1 0 FOP N terminal dimerisation domain VPS13_mid_rpt PF16910.5 KNE01011.1 - 5.9e-89 297.5 13.5 8e-84 280.7 0.7 5.5 5 2 0 5 5 5 2 Repeating coiled region of VPS13 SHR-BD PF06650.12 KNE01011.1 - 8.8e-89 297.5 0.6 3.8e-84 282.3 0.3 2.5 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 KNE01011.1 - 7.1e-73 245.3 8.7 7e-71 238.8 3.2 3.7 3 0 0 3 3 3 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KNE01011.1 - 1.3e-72 243.3 12.9 2.5e-68 229.4 0.8 3.3 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 KNE01011.1 - 2.5e-40 137.2 2.8 3e-40 136.9 0.4 2.6 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KNE01011.1 - 2.4e-05 24.6 0.0 7.4e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain CssAB PF16831.5 KNE01011.1 - 0.072 13.5 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 CS6 fimbrial subunits A and B, Coli surface antigen 6 Formyl_trans_N PF00551.19 KNE01012.1 - 6.8e-30 104.1 0.0 1.1e-29 103.5 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 KNE01012.1 - 9.1e-06 25.8 0.1 1.6e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain MFS_1 PF07690.16 KNE01014.1 - 2.9e-06 26.4 26.5 0.0002 20.4 11.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF21 PF01595.20 KNE01014.1 - 0.0067 16.1 0.6 0.4 10.4 0.3 2.9 3 0 0 3 3 3 1 Cyclin M transmembrane N-terminal domain CSN8_PSD8_EIF3K PF10075.9 KNE01015.1 - 7.3e-07 29.3 0.1 1.2e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Ran-binding PF05508.11 KNE01016.1 - 7.6e-05 21.8 0.3 8.8e-05 21.6 0.3 1.0 1 0 0 1 1 1 1 RanGTP-binding protein CLZ PF16526.5 KNE01016.1 - 0.032 14.6 1.1 2.1 8.8 0.1 2.1 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4349 PF14257.6 KNE01016.1 - 0.075 12.5 0.5 0.24 10.8 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) TPR_21 PF09976.9 KNE01016.1 - 0.08 12.6 0.2 0.1 12.3 0.2 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain Trp_syntA PF00290.20 KNE01017.1 - 9.9e-93 309.7 0.3 1.5e-92 309.1 0.3 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KNE01017.1 - 8.3e-48 163.3 1.1 1.3e-47 162.7 1.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rrn6 PF10214.9 KNE01018.1 - 2.3e-44 152.2 30.2 1.8e-42 145.9 30.2 2.1 1 1 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Glyco_hydro_63 PF03200.16 KNE01019.1 - 2.3e-178 593.9 2.1 2.2e-177 590.8 2.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KNE01019.1 - 4.2e-68 229.8 0.4 2.8e-67 227.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 KNE01019.1 - 6.3e-05 22.0 1.4 0.00012 21.1 1.4 1.3 1 0 0 1 1 1 1 Trehalase RP853 PF17542.2 KNE01019.1 - 0.028 13.6 0.0 0.059 12.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized RP853 CLTH PF10607.9 KNE01020.1 - 1.4e-28 99.6 5.5 1.6e-28 99.4 4.4 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KNE01020.1 - 0.0024 17.8 0.0 0.0055 16.6 0.0 1.6 1 0 0 1 1 1 1 LisH DCA16 PF15349.6 KNE01021.1 - 0.17 11.4 0.1 0.26 10.8 0.1 1.3 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 LAMTOR PF15454.6 KNE01023.1 - 2.4e-08 34.4 6.0 6e-08 33.2 6.0 1.7 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator LRR_4 PF12799.7 KNE01024.1 - 1.8e-07 31.3 31.0 0.0021 18.4 8.8 4.7 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KNE01024.1 - 3.7e-06 26.6 19.6 3.7e-06 26.6 19.6 5.2 3 1 3 6 6 6 4 Leucine rich repeat LRR_6 PF13516.6 KNE01024.1 - 0.00045 20.1 0.6 0.00045 20.1 0.6 5.1 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 KNE01024.1 - 0.00053 20.2 21.7 1.7 9.5 0.7 6.4 5 1 0 5 5 5 3 Leucine Rich Repeat AMMECR1 PF01871.17 KNE01025.1 - 9e-41 139.3 0.0 1.1e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 Zip PF02535.22 KNE01026.1 - 2.4e-62 211.1 6.3 2.8e-62 210.9 6.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter UCH PF00443.29 KNE01027.1 - 1.3e-51 175.6 0.0 2.8e-51 174.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KNE01027.1 - 4.2e-24 85.7 0.3 4e-18 66.1 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PMSR PF01625.21 KNE01028.1 - 8.5e-54 181.9 0.2 1e-53 181.7 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DNA_pol3_delta2 PF13177.6 KNE01029.1 - 2.4e-09 37.2 0.3 6.3e-09 35.8 0.3 1.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KNE01029.1 - 7.3e-07 29.3 0.1 1.6e-06 28.2 0.1 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 KNE01029.1 - 1.2e-06 29.0 0.6 4.5e-06 27.1 0.6 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KNE01029.1 - 0.00016 22.0 0.0 0.0013 19.0 0.0 2.4 2 1 1 3 3 3 1 AAA domain AAA_24 PF13479.6 KNE01029.1 - 0.0034 17.1 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KNE01029.1 - 0.013 14.6 0.0 0.031 13.4 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 KNE01029.1 - 0.038 13.4 0.0 0.25 10.7 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KNE01029.1 - 0.094 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Rep_fac_C PF08542.11 KNE01029.1 - 0.12 12.8 0.1 0.25 11.8 0.1 1.6 1 0 0 1 1 1 0 Replication factor C C-terminal domain AAA_16 PF13191.6 KNE01029.1 - 0.15 12.5 0.3 0.82 10.0 0.0 2.4 1 1 1 2 2 2 0 AAA ATPase domain Pmp3 PF01679.17 KNE01030.1 - 0.86 9.8 11.2 13 6.1 11.2 2.3 1 1 0 1 1 1 0 Proteolipid membrane potential modulator Pmp3 PF01679.17 KNE01031.1 - 1.8e-07 31.2 9.0 2.8e-07 30.6 9.0 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF3810 PF12725.7 KNE01031.1 - 0.16 11.3 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Ribosomal_60s PF00428.19 KNE01031.1 - 3.1 8.5 6.8 5.5 7.7 6.8 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Snf7 PF03357.21 KNE01032.1 - 4.1e-26 91.6 20.2 6.2e-26 91.0 20.2 1.2 1 0 0 1 1 1 1 Snf7 SKI PF01202.22 KNE01032.1 - 0.029 14.5 0.8 0.029 14.5 0.8 2.0 2 1 1 3 3 3 0 Shikimate kinase ZIP4_domain PF18292.1 KNE01032.1 - 0.094 12.6 7.1 0.84 9.5 0.5 2.1 1 1 1 2 2 2 0 Zinc transporter ZIP4 domain Eno-Rase_FAD_bd PF07055.12 KNE01032.1 - 0.35 11.3 4.8 0.19 12.1 1.8 2.1 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain DUF4172 PF13776.6 KNE01032.1 - 0.4 11.1 4.8 8.5 6.8 0.3 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4172) DUF4523 PF15023.6 KNE01032.1 - 0.46 10.3 4.5 0.45 10.3 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) Na_trans_assoc PF06512.13 KNE01032.1 - 0.6 10.3 5.2 0.86 9.9 5.2 1.3 1 1 0 1 1 1 0 Sodium ion transport-associated Cwf_Cwc_15 PF04889.12 KNE01033.1 - 0.05 13.3 10.0 0.076 12.7 10.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 KNE01033.1 - 0.12 11.7 6.5 0.18 11.2 6.5 1.3 1 0 0 1 1 1 0 BUD22 Rrp44_CSD1 PF17216.3 KNE01033.1 - 4.1 7.1 6.0 2.7 7.7 0.5 2.2 2 0 0 2 2 2 0 Rrp44-like cold shock domain PBP1_TM PF14812.6 KNE01033.1 - 5.3 7.5 13.0 0.33 11.4 5.7 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NESP55 PF06390.12 KNE01034.1 - 0.25 10.9 8.1 0.33 10.5 8.1 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Trypan_PARP PF05887.11 KNE01034.1 - 1.9 8.5 5.7 3.3 7.7 5.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) BLOC1_2 PF10046.9 KNE01035.1 - 1.2e-18 67.2 8.2 1.4e-18 67.0 8.2 1.0 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 KNE01035.1 - 0.007 16.4 2.9 0.0094 16.0 2.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) DUF4763 PF15960.5 KNE01035.1 - 0.0095 15.3 2.5 0.012 15.0 2.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4763) ATG16 PF08614.11 KNE01035.1 - 0.016 15.5 5.8 0.018 15.3 5.8 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KNE01035.1 - 0.04 12.8 7.5 0.044 12.7 7.5 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Ribosomal_L16 PF00252.18 KNE01036.1 - 1.5e-30 105.9 0.6 2.1e-30 105.5 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e tRNA-synt_2d PF01409.20 KNE01037.1 - 8.9e-52 176.0 0.3 8.1e-26 91.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KNE01037.1 - 1.5e-21 76.6 0.0 3.8e-21 75.3 0.0 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Flavodoxin_1 PF00258.25 KNE01038.1 - 6.4e-27 94.5 0.0 2.3e-26 92.7 0.0 1.9 3 0 0 3 3 3 1 Flavodoxin FAD_binding_1 PF00667.20 KNE01038.1 - 6.4e-23 81.5 0.0 9.7e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KNE01038.1 - 3.3e-13 50.2 0.0 5.8e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KNE01038.1 - 0.097 12.9 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain YycC PF14174.6 KNE01038.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 YycC-like protein Flavodoxin_3 PF12641.7 KNE01038.1 - 0.2 11.3 0.0 1 9.0 0.0 2.0 2 0 0 2 2 2 0 Flavodoxin domain Bromodomain PF00439.25 KNE01039.1 - 1.9e-35 120.8 3.6 9.8e-18 64.0 0.1 2.9 3 0 0 3 3 3 2 Bromodomain MnmE_helical PF12631.7 KNE01040.1 - 8.9e-40 137.1 0.1 1.1e-39 136.7 0.1 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 KNE01040.1 - 2.7e-37 127.6 0.0 4.6e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 KNE01040.1 - 4.5e-17 62.2 0.2 1.7e-16 60.3 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KNE01040.1 - 1.5e-07 31.1 0.1 2.4e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KNE01040.1 - 6.2e-07 29.5 0.1 0.028 14.3 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KNE01040.1 - 0.0029 17.7 0.2 0.19 11.8 0.0 2.9 2 1 1 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 KNE01040.1 - 0.0037 16.8 0.1 0.085 12.4 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 KNE01040.1 - 0.0074 16.3 0.1 0.076 13.0 0.0 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain DUF2443 PF10398.9 KNE01040.1 - 0.12 12.4 0.1 0.42 10.7 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) ParA PF10609.9 KNE01041.1 - 1.6e-94 316.0 0.2 1.9e-94 315.7 0.2 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KNE01041.1 - 1.5e-09 38.0 0.0 2.9e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 KNE01041.1 - 2.5e-07 30.2 0.0 3.4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.6 KNE01041.1 - 1.4e-06 28.3 3.3 5.4e-05 23.2 1.2 2.2 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 KNE01041.1 - 0.00011 21.7 0.1 0.053 13.0 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 KNE01041.1 - 0.00012 21.4 2.7 0.00085 18.6 1.4 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase APS_kinase PF01583.20 KNE01041.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.6 KNE01041.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KNE01041.1 - 0.24 10.6 0.2 0.39 9.9 0.2 1.3 1 0 0 1 1 1 0 NB-ARC domain CBP_BcsQ PF06564.12 KNE01041.1 - 0.46 9.9 1.4 5 6.5 0.1 2.6 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsQ CTP_transf_1 PF01148.20 KNE01044.1 - 5.9e-07 29.5 4.5 8.1e-07 29.1 4.5 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family ABC_membrane PF00664.23 KNE01046.1 - 5.2e-60 203.4 38.1 3.5e-36 125.3 23.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KNE01046.1 - 2.9e-49 167.1 0.8 1e-29 103.8 0.1 3.3 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KNE01046.1 - 4.4e-09 36.1 8.1 2.1e-05 24.0 1.0 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KNE01046.1 - 7.9e-07 29.1 0.5 0.0014 18.5 0.2 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KNE01046.1 - 1.7e-06 27.7 1.8 0.012 15.3 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KNE01046.1 - 1.4e-05 25.1 0.6 2.9 7.6 0.1 4.3 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KNE01046.1 - 4.5e-05 23.5 0.7 0.22 11.6 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KNE01046.1 - 4.5e-05 23.9 0.0 0.013 15.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 KNE01046.1 - 0.00074 18.9 0.0 0.15 11.3 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 KNE01046.1 - 0.00079 20.0 1.1 0.62 10.6 0.0 3.2 3 0 0 3 3 2 1 AAA domain T2SSE PF00437.20 KNE01046.1 - 0.0036 16.4 0.5 0.23 10.5 0.4 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 KNE01046.1 - 0.005 16.6 0.2 0.62 9.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 KNE01046.1 - 0.0054 17.2 20.4 0.19 12.2 0.1 4.3 3 1 1 4 4 3 2 AAA domain AAA_22 PF13401.6 KNE01046.1 - 0.0056 17.0 2.1 4.2 7.6 0.1 3.2 2 1 0 2 2 2 2 AAA domain cobW PF02492.19 KNE01046.1 - 0.0058 16.2 0.6 0.052 13.1 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 KNE01046.1 - 0.0078 16.6 0.1 1.4 9.4 0.0 3.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KNE01046.1 - 0.015 15.1 0.6 6.4 6.5 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein ATP_bind_1 PF03029.17 KNE01046.1 - 0.024 14.4 0.1 11 5.7 0.0 3.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Vps51 PF08700.11 KNE01046.1 - 0.041 14.0 2.6 0.087 12.9 0.3 2.5 2 0 0 2 2 2 0 Vps51/Vps67 Roc PF08477.13 KNE01046.1 - 0.12 12.6 0.2 7.2 6.9 0.1 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KNE01046.1 - 0.16 12.0 5.1 1.7 8.7 0.1 3.1 3 0 0 3 3 2 0 Dynamin family Sensor PF13796.6 KNE01046.1 - 0.25 11.4 11.5 0.24 11.5 2.6 2.9 2 1 0 2 2 2 0 Putative sensor S_4TM PF18159.1 KNE01046.1 - 2.3 7.4 8.8 0.62 9.3 0.2 3.3 3 0 0 3 3 3 0 SMODS-associating 4TM effector domain PHD PF00628.29 KNE01048.1 - 1.7e-07 31.0 12.3 3.4e-07 30.0 12.3 1.5 1 0 0 1 1 1 1 PHD-finger Urease_beta PF00699.20 KNE01048.1 - 0.13 12.3 0.1 0.65 10.1 0.0 2.1 2 0 0 2 2 2 0 Urease beta subunit Pam16 PF03656.13 KNE01049.1 - 3.9e-33 114.2 2.2 4.4e-33 114.0 2.2 1.0 1 0 0 1 1 1 1 Pam16 IBR PF01485.21 KNE01051.1 - 5.9e-18 64.9 40.9 1.9e-09 37.6 2.4 4.2 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KNE01051.1 - 0.013 15.3 8.5 0.013 15.3 8.5 5.3 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DUF2666 PF10869.8 KNE01051.1 - 0.051 13.8 0.5 0.12 12.6 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) zf-RAG1 PF10426.9 KNE01051.1 - 0.29 11.3 6.3 31 4.8 0.1 3.7 3 0 0 3 3 3 0 Recombination-activating protein 1 zinc-finger domain THRAP3_BCLAF1 PF15440.6 KNE01053.1 - 0.02 14.0 0.3 0.025 13.6 0.3 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Sporozoite_P67 PF05642.11 KNE01053.1 - 0.27 9.3 0.6 0.33 9.0 0.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen UNC-50 PF05216.13 KNE01054.1 - 1.6e-87 292.8 20.0 1.8e-87 292.5 20.0 1.0 1 0 0 1 1 1 1 UNC-50 family DUF3808 PF10300.9 KNE01055.1 - 1.7e-124 416.2 1.1 2.2e-124 415.8 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 KNE01055.1 - 0.22 11.7 3.7 5 7.5 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L4 PF00573.22 KNE01061.1 - 2e-42 145.1 2.2 3.2e-42 144.4 2.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KNE01061.1 - 6.3e-30 103.0 4.9 1.3e-27 95.6 2.2 2.5 2 0 0 2 2 2 2 60S ribosomal protein L4 C-terminal domain Pro_isomerase PF00160.21 KNE01062.1 - 2.2e-29 102.8 0.1 8.9e-29 100.8 0.1 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KNE01062.1 - 1e-06 28.3 3.5 0.0065 16.5 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KNE01062.1 - 2.4e-06 27.1 1.1 0.0044 16.8 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KNE01062.1 - 0.0087 16.2 0.1 0.0087 16.2 0.1 3.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KNE01062.1 - 0.0098 16.5 0.3 0.033 14.8 0.3 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KNE01062.1 - 0.012 16.3 0.1 0.084 13.7 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KNE01062.1 - 0.038 14.5 1.0 1.8 9.2 0.6 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 KNE01062.1 - 0.043 14.0 0.1 0.088 13.0 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KNE01062.1 - 0.074 13.4 0.4 0.46 10.8 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TraE PF05309.11 KNE01062.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 TraE protein Fis1_TPR_C PF14853.6 KNE01062.1 - 0.22 11.6 4.4 0.15 12.1 0.6 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat SQS_PSY PF00494.19 KNE01063.1 - 6.2e-20 71.8 0.0 9.2e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase EMG1 PF03587.14 KNE01063.1 - 0.096 12.3 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 EMG1/NEP1 methyltransferase GABP-alpha PF11620.8 KNE01063.1 - 0.11 12.7 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 GA-binding protein alpha chain Sec7 PF01369.20 KNE01064.1 - 4.6e-66 222.0 0.4 8.5e-66 221.1 0.4 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KNE01064.1 - 7.4e-14 52.0 1.2 7.4e-14 52.0 1.2 3.6 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3361 PF11841.8 KNE01064.1 - 0.0015 18.4 0.5 0.0015 18.4 0.5 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF3361) OMPdecase PF00215.24 KNE01065.1 - 5.3e-78 261.7 0.0 6.1e-78 261.5 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Mito_carr PF00153.27 KNE01066.1 - 5.2e-13 48.7 3.4 3.7e-08 33.2 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Vps26 PF03643.15 KNE01068.1 - 1.4e-109 365.4 1.2 1.6e-109 365.2 1.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KNE01068.1 - 3.6e-05 23.8 0.5 0.037 14.1 0.0 2.4 1 1 1 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Gp_dh_C PF02800.20 KNE01069.1 - 6.5e-71 237.0 0.0 9.4e-71 236.5 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KNE01069.1 - 5.4e-40 135.8 0.1 1.3e-39 134.6 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KNE01069.1 - 0.016 15.3 0.9 0.067 13.3 0.3 2.5 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 KNE01069.1 - 0.029 13.7 0.0 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RasGEF PF00617.19 KNE01071.1 - 1.7e-55 188.0 3.8 5.3e-55 186.4 2.5 2.5 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KNE01071.1 - 1.2e-21 76.9 0.5 4.9e-21 75.0 0.0 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.28 KNE01071.1 - 5.2e-15 54.8 0.0 1.2e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KNE01071.1 - 2.4e-10 40.1 0.1 5.1e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KNE01071.1 - 1e-06 28.3 0.0 3.2e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain GRIP PF01465.20 KNE01072.1 - 3.8e-13 49.1 1.5 5.3e-13 48.6 0.1 2.1 2 0 0 2 2 2 1 GRIP domain THOC7 PF05615.13 KNE01072.1 - 0.00059 20.1 16.7 0.00059 20.1 16.7 9.3 1 1 5 6 6 6 1 Tho complex subunit 7 KASH_CCD PF14662.6 KNE01072.1 - 0.00085 19.2 21.9 0.00085 19.2 21.9 7.5 2 1 4 7 7 7 2 Coiled-coil region of CCDC155 or KASH Filament PF00038.21 KNE01072.1 - 0.00085 19.0 19.6 0.00085 19.0 19.6 6.9 1 1 4 5 5 5 2 Intermediate filament protein FAM184 PF15665.5 KNE01072.1 - 0.0012 18.7 22.7 0.0012 18.7 22.7 7.7 2 1 5 7 7 7 2 Family with sequence similarity 184, A and B TACC_C PF05010.14 KNE01072.1 - 0.0019 18.0 21.4 0.0019 18.0 21.4 7.0 1 1 5 7 7 7 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FliJ PF02050.16 KNE01072.1 - 0.0026 18.0 11.8 0.0026 18.0 11.8 10.2 3 2 6 9 9 9 3 Flagellar FliJ protein SlyX PF04102.12 KNE01072.1 - 0.0077 16.8 3.4 0.0077 16.8 3.4 12.6 8 3 4 12 12 12 2 SlyX GAS PF13851.6 KNE01072.1 - 0.85 8.9 169.5 0.33 10.3 16.5 7.7 1 1 4 7 7 7 0 Growth-arrest specific micro-tubule binding FUSC PF04632.12 KNE01072.1 - 6.6 5.1 34.9 0.24 9.9 3.3 4.6 2 1 1 4 4 4 0 Fusaric acid resistance protein family TYW3 PF02676.14 KNE01073.1 - 1.9e-64 216.9 0.0 2.6e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 zf-RING_2 PF13639.6 KNE01074.1 - 7.9e-10 38.9 12.7 6e-09 36.1 4.5 2.3 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.7 KNE01074.1 - 1.5e-07 31.5 2.7 1.5e-07 31.5 2.7 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KNE01074.1 - 9.4e-07 28.6 2.0 9.4e-07 28.6 2.0 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KNE01074.1 - 1.3e-06 28.3 8.0 1.7e-05 24.7 1.6 2.6 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KNE01074.1 - 2.4e-06 27.3 10.5 4.4e-06 26.4 2.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KNE01074.1 - 0.00011 22.0 9.1 0.00011 22.0 1.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KNE01074.1 - 0.00015 21.5 10.4 0.00027 20.8 2.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KNE01074.1 - 0.00049 20.2 2.0 0.00049 20.2 2.0 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KNE01074.1 - 0.00052 19.9 8.6 0.00086 19.2 1.5 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KNE01074.1 - 0.0055 16.7 4.9 0.038 14.0 0.8 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.15 KNE01074.1 - 0.09 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-RING_11 PF17123.5 KNE01074.1 - 0.17 11.6 5.9 1.9 8.3 0.3 2.5 2 0 0 2 2 2 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 KNE01074.1 - 0.23 11.1 4.6 0.07 12.8 1.7 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KNE01074.1 - 1.2 9.4 10.1 1.4e+03 -0.4 10.1 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 KNE01074.1 - 4.9 7.4 6.0 0.73 10.0 0.8 2.1 2 0 0 2 2 2 0 RING-variant domain INTAP PF16617.5 KNE01076.1 - 0.0011 19.3 0.4 0.0013 19.1 0.4 1.1 1 0 0 1 1 1 1 Intersectin and clathrin adaptor AP2 binding region Complex1_30kDa PF00329.19 KNE01083.1 - 3.8e-45 153.4 0.0 6.8e-45 152.6 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit End3 PF12761.7 KNE01084.1 - 2.2e-69 233.7 5.7 2.8e-69 233.3 5.7 1.1 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 KNE01084.1 - 1.3e-55 185.7 0.1 1.5e-54 182.3 0.1 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KNE01084.1 - 0.00015 21.0 1.7 0.00046 19.6 0.2 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KNE01084.1 - 0.00022 21.6 0.1 0.0017 18.8 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KNE01084.1 - 0.02 14.7 0.1 0.043 13.7 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain pair DUF16 PF01519.16 KNE01084.1 - 0.041 14.4 1.4 0.09 13.3 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF16 Prominin PF05478.11 KNE01084.1 - 0.058 11.4 3.1 0.077 10.9 3.1 1.1 1 0 0 1 1 1 0 Prominin EF-hand_5 PF13202.6 KNE01084.1 - 0.068 12.7 0.4 0.7 9.5 0.1 2.5 2 0 0 2 2 2 0 EF hand DUF1664 PF07889.12 KNE01084.1 - 0.098 12.7 2.1 0.18 11.8 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) EF-hand_6 PF13405.6 KNE01084.1 - 0.26 11.3 0.2 0.26 11.3 0.2 2.5 3 0 0 3 3 2 0 EF-hand domain UPF0242 PF06785.11 KNE01084.1 - 0.27 11.3 11.2 0.11 12.5 6.6 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 KNE01084.1 - 0.3 11.3 3.8 0.49 10.6 3.8 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family KLRAQ PF10205.9 KNE01084.1 - 1.8 8.9 7.6 9 6.6 0.1 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein APG6_N PF17675.1 KNE01084.1 - 8.7 6.9 11.8 18 5.9 5.6 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region WD40 PF00400.32 KNE01085.1 - 6.4e-07 30.0 11.1 0.017 16.0 0.3 5.7 5 1 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.8 KNE01085.1 - 0.0016 17.2 0.1 0.024 13.3 0.1 2.1 2 0 0 2 2 2 1 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KNE01085.1 - 0.092 13.3 0.1 0.64 10.6 0.0 2.5 3 0 0 3 3 3 0 PQQ-like domain YcxB PF14317.6 KNE01086.1 - 0.1 12.3 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 YcxB-like protein NMT_C PF02799.15 KNE01088.1 - 1.4e-80 269.7 0.2 2.2e-80 269.1 0.2 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KNE01088.1 - 3.4e-72 241.5 0.1 1.1e-71 239.8 0.0 1.8 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 KNE01088.1 - 0.0011 19.0 0.0 0.086 12.9 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KNE01088.1 - 0.025 14.8 0.0 0.069 13.4 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family F-box-like PF12937.7 KNE01089.1 - 1.2e-05 25.1 0.1 2.8e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like EndoU_bacteria PF14436.6 KNE01089.1 - 0.14 12.5 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial EndoU nuclease eIF-3c_N PF05470.12 KNE01091.1 - 4.1e-139 464.6 29.5 4e-112 375.5 4.3 3.1 2 1 0 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KNE01091.1 - 1e-07 32.4 0.3 1e-07 32.4 0.3 3.3 3 0 0 3 3 3 1 PCI domain DDRGK PF09756.9 KNE01091.1 - 0.027 14.1 0.2 0.027 14.1 0.2 3.4 2 1 1 3 3 3 0 DDRGK domain HTH_40 PF14493.6 KNE01091.1 - 0.044 14.2 0.5 1.1 9.8 0.2 3.2 2 0 0 2 2 2 0 Helix-turn-helix domain ANAPC3 PF12895.7 KNE01091.1 - 0.083 13.1 2.1 0.81 10.0 0.0 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 FeoC PF09012.10 KNE01091.1 - 0.092 12.8 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 FeoC like transcriptional regulator Neur_chan_memb PF02932.16 KNE01091.1 - 0.27 11.3 2.1 3.6 7.6 0.4 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region MID_MedPIWI PF18296.1 KNE01091.1 - 2.1 8.1 12.5 0.29 10.9 7.1 2.1 2 0 0 2 2 2 0 MID domain of medPIWI ATP_bind_3 PF01171.20 KNE01092.1 - 7.5e-18 64.9 0.0 1.3e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 KNE01092.1 - 6.3e-16 57.6 3.3 6.3e-16 57.6 3.3 3.7 4 0 0 4 4 4 1 Zinc-ribbon tRNA_Me_trans PF03054.16 KNE01092.1 - 0.059 12.1 0.1 0.11 11.3 0.1 1.4 1 1 0 1 1 1 0 tRNA methyl transferase DUF2616 PF11077.8 KNE01092.1 - 0.28 10.9 5.9 1.6 8.4 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) Cytochrom_c3_2 PF14537.6 KNE01092.1 - 5.6 7.5 7.6 5 7.7 0.6 2.5 2 0 0 2 2 2 0 Cytochrome c3 adh_short PF00106.25 KNE01093.1 - 4.2e-51 173.2 0.1 5.5e-51 172.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNE01093.1 - 1.1e-34 120.0 0.2 1.4e-34 119.7 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNE01093.1 - 4e-12 46.4 0.0 6e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KNE01093.1 - 0.0056 15.9 0.1 0.012 14.8 0.1 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KNE01093.1 - 0.036 13.5 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KNE01093.1 - 0.053 12.9 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ThiF PF00899.21 KNE01093.1 - 0.12 11.7 0.2 0.25 10.6 0.2 1.5 1 0 0 1 1 1 0 ThiF family CBM_21 PF03370.13 KNE01094.1 - 1e-24 86.9 3.3 2.1e-24 85.9 3.3 1.5 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KNE01094.1 - 2.9e-10 40.6 1.8 6.6e-10 39.4 1.8 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) DrsE PF02635.15 KNE01095.1 - 0.064 13.6 0.0 0.071 13.5 0.0 1.2 1 0 0 1 1 1 0 DsrE/DsrF-like family tRNA-synt_1c PF00749.21 KNE01099.1 - 1.1e-111 372.7 0.0 6.8e-111 370.1 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 KNE01099.1 - 1.4e-47 161.7 3.6 2.3e-47 161.0 3.6 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 KNE01099.1 - 2.8e-30 105.5 1.2 6.7e-29 101.0 0.1 2.8 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 KNE01099.1 - 3.9e-12 46.9 3.0 1.1e-11 45.5 3.0 1.8 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Abhydrolase_1 PF00561.20 KNE01101.1 - 3.3e-18 66.2 0.2 1.5e-14 54.2 0.0 2.5 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNE01101.1 - 1.5e-15 58.4 0.0 2.9e-15 57.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNE01101.1 - 5e-14 52.1 0.0 4e-10 39.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 KNE01101.1 - 0.0021 17.7 0.0 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 KNE01101.1 - 0.012 15.4 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 KNE01101.1 - 0.02 15.0 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain DUF915 PF06028.11 KNE01101.1 - 0.033 13.5 0.0 0.073 12.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Plus-3 PF03126.18 KNE01102.1 - 1.1e-23 83.8 2.2 1.3e-23 83.6 0.3 2.2 2 0 0 2 2 2 1 Plus-3 domain Lectin_C PF00059.21 KNE01104.1 - 0.1 13.4 0.1 0.1 13.3 0.1 1.1 1 0 0 1 1 1 0 Lectin C-type domain DUF1129 PF06570.11 KNE01104.1 - 0.11 12.0 0.0 0.11 11.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) ACBP PF00887.19 KNE01107.1 - 1e-11 44.9 0.6 1.1e-11 44.8 0.6 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein DUF2781 PF10914.8 KNE01108.1 - 4e-40 137.6 11.9 5.6e-40 137.1 11.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) GRDP-like PF07173.12 KNE01109.1 - 7.7e-09 36.3 0.1 1.4e-08 35.5 0.1 1.4 1 0 0 1 1 1 1 Glycine-rich domain-containing protein-like PUMA PF15826.5 KNE01111.1 - 0.055 13.6 0.2 0.055 13.6 0.2 1.0 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis RNase_T PF00929.24 KNE01112.1 - 1.3e-33 116.9 0.0 1.7e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 Exonuclease Pkinase PF00069.25 KNE01113.1 - 4.6e-60 203.2 0.0 2.1e-38 132.2 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNE01113.1 - 3e-27 95.5 0.2 4.2e-21 75.4 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KNE01113.1 - 3.8e-10 39.9 0.1 8.2e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KNE01113.1 - 0.0001 21.7 0.1 0.0017 17.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KNE01113.1 - 0.0013 18.8 0.1 0.016 15.1 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KNE01113.1 - 0.0059 15.6 0.1 0.031 13.2 0.1 2.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KNE01113.1 - 0.022 14.1 0.7 0.045 13.1 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KNE01113.1 - 0.027 13.5 0.0 0.06 12.4 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 AAA_lid_11 PF18198.1 KNE01113.1 - 0.04 13.7 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain GlutR_dimer PF00745.20 KNE01113.1 - 0.068 13.6 3.3 0.2 12.1 0.9 2.8 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain bZIP_2 PF07716.15 KNE01114.1 - 1.3e-10 41.2 12.9 1.3e-10 41.2 12.9 2.8 3 0 0 3 3 3 1 Basic region leucine zipper SUIM_assoc PF16619.5 KNE01114.1 - 5.1 7.2 14.1 0.6 10.2 1.0 2.8 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PSP1 PF04468.12 KNE01115.1 - 1.5e-33 114.9 1.6 2.9e-33 114.0 1.6 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region FSA_C PF10479.9 KNE01115.1 - 0.2 9.7 1.5 0.28 9.3 1.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SRF-TF PF00319.18 KNE01120.1 - 4.3e-21 74.1 0.1 6.1e-21 73.7 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Synaphin PF05835.12 KNE01120.1 - 0.16 12.2 7.4 0.17 12.2 1.0 2.4 2 0 0 2 2 2 0 Synaphin protein AP-5_subunit_s1 PF15001.6 KNE01120.1 - 0.34 10.9 2.7 11 5.9 0.0 2.1 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 Pex14_N PF04695.13 KNE01120.1 - 4 8.1 16.5 0.7 10.5 12.7 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PWWP PF00855.17 KNE01121.1 - 6.7e-19 68.1 0.1 2.1e-18 66.5 0.1 1.9 1 0 0 1 1 1 1 PWWP domain DUF4594 PF15266.6 KNE01121.1 - 0.85 9.9 7.9 1.8 8.9 7.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4594) WD40 PF00400.32 KNE01122.1 - 0.00034 21.4 1.2 2.3 9.2 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat IKI3 PF04762.12 KNE01122.1 - 0.26 9.2 0.1 0.33 8.9 0.1 1.1 1 0 0 1 1 1 0 IKI3 family Phosphorylase PF00343.20 KNE01124.1 - 0 1017.0 0.0 0 1016.7 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase DUF4709 PF15821.5 KNE01124.1 - 0.1 12.8 0.3 1.2e+02 3.0 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF4709) Peptidase_S10 PF00450.22 KNE01126.1 - 9e-103 344.9 0.1 1.2e-102 344.5 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Ribosomal_L4 PF00573.22 KNE01127.1 - 8.7e-45 152.8 0.0 1e-44 152.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Herpes_UL14 PF03580.14 KNE01127.1 - 0.028 14.7 0.1 0.044 14.0 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL14-like protein Ribosomal_S13 PF00416.22 KNE01128.1 - 2.3e-55 186.4 2.7 2.7e-55 186.2 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KNE01128.1 - 0.0063 15.3 0.0 0.0071 15.2 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NAD_binding_4 PF07993.12 KNE01130.1 - 2.5e-69 233.3 0.0 3.6e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KNE01130.1 - 1.4e-65 221.6 0.0 2e-65 221.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KNE01130.1 - 4.9e-11 42.8 0.0 1.2e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KNE01130.1 - 4.4e-09 36.2 0.0 8.5e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Condensation PF00668.20 KNE01130.1 - 2.4e-05 23.2 0.8 0.00015 20.6 0.8 2.1 1 1 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.6 KNE01130.1 - 0.0006 20.7 0.1 0.0023 18.9 0.1 2.1 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 KNE01130.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KNE01130.1 - 0.022 13.8 0.0 0.083 11.9 0.0 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KNE01130.1 - 0.031 13.4 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Vta1 PF04652.16 KNE01131.1 - 0.15 12.0 1.5 0.32 10.9 0.5 1.8 1 1 1 2 2 2 0 Vta1 like Exonuc_VII_L PF02601.15 KNE01131.1 - 0.19 11.3 3.7 0.31 10.6 3.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit CLZ PF16526.5 KNE01131.1 - 0.2 12.0 10.1 2.3 8.7 1.7 3.4 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CENP-F_leu_zip PF10473.9 KNE01131.1 - 0.47 10.5 9.2 0.89 9.6 9.2 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CorA PF01544.18 KNE01131.1 - 0.85 8.9 6.5 0.91 8.8 2.7 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein HIP1_clath_bdg PF16515.5 KNE01131.1 - 1.1 10.0 7.1 0.4 11.3 2.9 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fungal_trans PF04082.18 KNE01132.1 - 2.8e-25 88.9 0.0 4.5e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNE01132.1 - 5e-06 26.5 11.6 9.6e-06 25.6 11.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KNE01132.1 - 0.0097 16.0 0.5 0.026 14.7 0.5 1.7 1 0 0 1 1 1 1 Gal4-like dimerisation domain adh_short_C2 PF13561.6 KNE01134.1 - 4.3e-58 196.6 0.4 5.1e-58 196.4 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNE01134.1 - 2.4e-42 144.6 0.4 3.1e-42 144.3 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KNE01134.1 - 4.4e-13 49.5 0.3 7.9e-13 48.7 0.3 1.3 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KNE01134.1 - 0.014 14.8 0.2 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KNE01134.1 - 0.068 12.6 1.0 0.43 10.0 1.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_N PF08240.12 KNE01136.1 - 1.8e-29 101.8 1.1 3.7e-29 100.8 1.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KNE01136.1 - 3.4e-22 78.8 0.0 7.4e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KNE01136.1 - 3.1e-08 33.4 0.3 0.0053 16.3 0.0 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KNE01136.1 - 2.4e-06 28.6 0.0 9.4e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KNE01136.1 - 0.00057 20.5 0.0 0.0013 19.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 KNE01136.1 - 0.0082 15.7 0.2 0.016 14.8 0.2 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_11 PF08241.12 KNE01136.1 - 0.015 15.9 0.0 0.033 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 KNE01136.1 - 0.016 14.6 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_31 PF13847.6 KNE01136.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain adh_short_C2 PF13561.6 KNE01137.1 - 8.1e-60 202.3 0.2 1e-59 202.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNE01137.1 - 2.9e-45 154.2 0.8 3.4e-45 153.9 0.8 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KNE01137.1 - 9.3e-15 55.0 0.2 1.4e-14 54.4 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KNE01137.1 - 0.004 16.6 0.0 0.0055 16.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KNE01137.1 - 0.011 14.7 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KNE01137.1 - 0.014 15.3 0.1 0.019 14.9 0.1 1.4 1 1 0 1 1 1 0 NAD(P)H-binding DapB_N PF01113.20 KNE01137.1 - 0.015 15.4 0.1 0.033 14.3 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 KNE01137.1 - 0.018 14.2 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KNE01137.1 - 0.02 15.2 0.1 0.038 14.3 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Glyco_hydro_99 PF16317.5 KNE01137.1 - 0.08 12.0 0.2 0.34 10.0 0.0 1.9 1 1 1 2 2 2 0 Glycosyl hydrolase family 99 GDP_Man_Dehyd PF16363.5 KNE01137.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase PDEase_I PF00233.19 KNE01139.1 - 3.1e-52 177.7 0.8 2.2e-45 155.2 0.0 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase SAM_2 PF07647.17 KNE01140.1 - 1.5e-06 28.2 0.1 3.4e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KNE01140.1 - 3.3e-05 24.2 0.1 8.1e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4253 PF14062.6 KNE01140.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) IGR PF09597.10 KNE01140.1 - 0.2 11.8 0.1 0.41 10.8 0.1 1.5 1 0 0 1 1 1 0 IGR protein motif Synaptobrevin PF00957.21 KNE01141.1 - 1.5e-15 56.7 0.7 2.6e-15 56.0 0.7 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KNE01141.1 - 6.8e-11 42.1 0.0 1.2e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Ras PF00071.22 KNE01142.1 - 4.2e-37 127.2 0.0 7.7e-37 126.4 0.0 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KNE01142.1 - 2.1e-29 102.2 0.0 2.1e-28 98.9 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNE01142.1 - 1.9e-08 34.0 0.2 7e-08 32.1 0.2 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KNE01142.1 - 1.5e-05 24.6 0.0 2.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KNE01142.1 - 0.00074 19.6 0.0 0.0015 18.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KNE01142.1 - 0.0012 18.2 0.0 0.0044 16.4 0.0 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KNE01142.1 - 0.014 15.3 0.1 1 9.2 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KNE01142.1 - 0.046 14.1 0.0 0.089 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KNE01142.1 - 0.17 12.2 0.0 0.94 9.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KNE01142.1 - 0.18 11.8 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CHCH PF06747.13 KNE01144.1 - 8.2e-09 35.4 2.9 1.5e-08 34.6 2.9 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KNE01144.1 - 0.0088 16.4 3.4 0.0088 16.4 3.4 1.8 2 0 0 2 2 2 1 GCK domain PT PF04886.12 KNE01144.1 - 0.04 13.4 5.3 0.4 10.3 0.3 2.5 2 0 0 2 2 2 0 PT repeat ADSL_C PF10397.9 KNE01144.1 - 0.052 14.1 0.9 0.72 10.4 0.2 2.1 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminus eIF-3c_N PF05470.12 KNE01144.1 - 8.2 4.6 8.4 0.49 8.6 0.2 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SpoVAE PF14097.6 KNE01145.1 - 0.076 12.7 0.0 0.089 12.4 0.0 1.1 1 0 0 1 1 1 0 Stage V sporulation protein AE1 Fer4_20 PF14691.6 KNE01145.1 - 0.15 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster G-patch PF01585.23 KNE01146.1 - 1.3e-12 47.4 5.2 2.2e-12 46.7 5.2 1.3 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KNE01146.1 - 1.2e-06 28.5 1.5 2.2e-06 27.6 1.5 1.4 1 0 0 1 1 1 1 G-patch domain KTSC PF13619.6 KNE01146.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 KTSC domain Glyco_transf_41 PF13844.6 KNE01146.1 - 0.081 11.3 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 APG17 PF04108.12 KNE01147.1 - 8.1e-61 206.3 13.6 1e-60 206.0 13.6 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF1835 PF08874.10 KNE01147.1 - 0.056 13.7 0.1 0.29 11.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1835) DUF1140 PF06600.11 KNE01147.1 - 1.3 9.5 4.5 0.71 10.3 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1140) MbeD_MobD PF04899.12 KNE01147.1 - 5.5 7.2 10.0 12 6.1 0.2 3.5 3 1 1 4 4 4 0 MbeD/MobD like CDC73_C PF05179.14 KNE01148.1 - 3.6e-49 166.5 0.9 7.8e-49 165.4 0.9 1.6 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal tRNA-synt_2b PF00587.25 KNE01149.1 - 5.8e-40 137.2 0.0 9.2e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KNE01149.1 - 7.5e-17 61.3 0.3 1.4e-16 60.4 0.3 1.4 1 0 0 1 1 1 1 Anticodon binding domain Ribosomal_S3_C PF00189.20 KNE01149.1 - 0.14 12.7 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S3, C-terminal domain INO80_Ies4 PF08193.11 KNE01150.1 - 1.8e-09 38.0 6.3 2.3e-08 34.4 1.9 2.1 1 1 0 2 2 2 2 INO80 complex subunit Ies4 DUF202 PF02656.15 KNE01151.1 - 0.0017 18.7 2.0 0.004 17.6 2.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF202) COX4_pro_2 PF07835.12 KNE01151.1 - 0.054 13.6 1.7 0.13 12.4 0.0 2.4 3 0 0 3 3 3 0 Bacterial aa3 type cytochrome c oxidase subunit IV MDM31_MDM32 PF08118.11 KNE01152.1 - 8.1e-213 707.8 4.3 9.2e-213 707.7 4.3 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Aminotran_5 PF00266.19 KNE01153.1 - 6.3e-17 61.6 0.0 9.3e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KNE01153.1 - 0.00017 20.9 0.0 0.00025 20.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KNE01153.1 - 0.0039 16.5 0.1 0.009 15.4 0.1 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KNE01153.1 - 0.027 13.0 0.0 0.039 12.5 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Cellulase PF00150.18 KNE01154.1 - 3.5e-10 39.8 11.5 1.4e-09 37.8 11.5 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ribosomal_60s PF00428.19 KNE01158.1 - 4e-25 88.2 14.6 4.8e-25 88.0 14.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_L13e PF01294.18 KNE01159.1 - 1e-65 221.0 8.8 1.4e-65 220.5 8.1 1.6 1 1 0 1 1 1 1 Ribosomal protein L13e RIC1 PF07064.13 KNE01160.1 - 2.1e-29 102.7 2.0 4.1e-29 101.7 2.0 1.5 1 0 0 1 1 1 1 RIC1 BBS2_N PF14781.6 KNE01160.1 - 0.54 10.2 5.8 0.33 10.9 0.3 3.3 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, N-terminal Complex1_LYR PF05347.15 KNE01161.1 - 1.3e-11 44.4 0.7 2.2e-11 43.6 0.7 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KNE01161.1 - 0.0003 21.5 1.0 0.00049 20.8 1.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Tubulin_C PF03953.17 KNE01162.1 - 5e-42 143.0 0.0 8.3e-42 142.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 KNE01162.1 - 2.6e-33 115.9 0.0 5e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 KNE01162.1 - 0.00099 18.8 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KNE01162.1 - 0.0041 16.4 0.0 0.0092 15.2 0.0 1.6 1 0 0 1 1 1 1 Tubulin like SNARE PF05739.19 KNE01163.1 - 5e-13 48.8 0.0 1.7e-12 47.1 0.1 1.9 2 0 0 2 2 2 1 SNARE domain DUF16 PF01519.16 KNE01163.1 - 9.9e-05 22.8 1.1 9.9e-05 22.8 1.1 2.6 2 1 0 2 2 2 1 Protein of unknown function DUF16 Syntaxin PF00804.25 KNE01163.1 - 0.00028 20.6 9.7 0.00045 19.9 0.2 2.8 3 0 0 3 3 3 2 Syntaxin Syntaxin-5_N PF11416.8 KNE01163.1 - 0.0017 17.5 0.2 0.0053 15.9 0.2 1.8 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain FlaC_arch PF05377.11 KNE01163.1 - 0.0081 16.5 0.3 0.0081 16.5 0.3 3.4 2 2 1 3 3 3 1 Flagella accessory protein C (FlaC) MCPsignal PF00015.21 KNE01163.1 - 0.011 15.6 0.9 0.011 15.6 0.9 2.4 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Serine_rich PF08824.10 KNE01163.1 - 0.02 14.9 1.8 4.8 7.2 0.1 2.3 2 0 0 2 2 2 0 Serine rich protein interaction domain Muted PF14942.6 KNE01163.1 - 0.021 15.2 2.5 0.021 15.2 2.5 2.8 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein Syntaxin-18_N PF10496.9 KNE01163.1 - 0.057 13.7 3.1 0.059 13.6 0.3 2.3 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus V-SNARE PF05008.15 KNE01163.1 - 0.39 11.1 7.6 1 9.8 0.2 3.3 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF745 PF05335.13 KNE01163.1 - 0.45 10.2 8.6 1.3 8.7 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF745) ATP-synt_G PF04718.15 KNE01163.1 - 0.49 11.2 2.2 16 6.4 0.1 2.7 2 0 0 2 2 2 0 Mitochondrial ATP synthase g subunit Osmo_CC PF08946.10 KNE01163.1 - 1.5 9.1 5.6 2.5 8.4 0.3 3.3 3 0 0 3 3 3 0 Osmosensory transporter coiled coil DUF1664 PF07889.12 KNE01163.1 - 2.3 8.2 7.0 1.4 8.9 1.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF148 PF02520.17 KNE01163.1 - 6 7.0 12.6 6.3 7.0 2.4 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF148 Snf7 PF03357.21 KNE01164.1 - 3e-42 144.1 22.7 3e-42 144.1 22.7 1.9 1 1 1 2 2 2 1 Snf7 DUF4407 PF14362.6 KNE01164.1 - 0.26 10.6 21.7 0.027 13.8 9.6 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) DASH_Dad4 PF08650.10 KNE01164.1 - 0.9 9.6 7.5 0.4 10.7 1.4 2.9 3 0 0 3 3 3 0 DASH complex subunit Dad4 DUF2730 PF10805.8 KNE01164.1 - 2.1 8.5 12.7 0.057 13.5 2.6 2.5 2 1 0 3 3 3 0 Protein of unknown function (DUF2730) Osmo_CC PF08946.10 KNE01164.1 - 2.6 8.4 18.1 5.3 7.4 0.5 4.5 4 0 0 4 4 4 0 Osmosensory transporter coiled coil DivIC PF04977.15 KNE01164.1 - 3.1 7.6 19.4 1.9 8.3 1.5 4.0 2 1 1 4 4 4 0 Septum formation initiator ISG65-75 PF11727.8 KNE01164.1 - 3.7 6.7 18.8 0.052 12.8 4.8 2.4 1 1 0 2 2 2 0 Invariant surface glycoprotein DUF3984 PF13136.6 KNE01164.1 - 4.2 6.7 9.1 0.63 9.4 5.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3984) ArAE_2_N PF10337.9 KNE01164.1 - 7.9 5.4 8.0 10 5.0 8.0 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal RNA_pol PF00940.19 KNE01165.1 - 3.7e-179 595.9 0.0 6.9e-179 595.0 0.0 1.5 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KNE01165.1 - 8.3e-95 318.0 0.2 1.8e-94 316.9 0.2 1.6 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal TcdB_N PF12918.7 KNE01165.1 - 0.077 13.3 0.1 0.44 10.9 0.1 2.4 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain Mob1_phocein PF03637.17 KNE01166.1 - 7.2e-69 231.1 0.8 8.3e-69 230.9 0.8 1.0 1 0 0 1 1 1 1 Mob1/phocein family PS_Dcarbxylase PF02666.15 KNE01168.1 - 4.4e-75 251.6 0.0 2.5e-73 245.9 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Big_5 PF13205.6 KNE01168.1 - 0.0022 18.6 0.4 0.0044 17.7 0.4 1.4 1 0 0 1 1 1 1 Bacterial Ig-like domain NADH_oxidored PF08040.11 KNE01168.1 - 0.025 14.3 0.0 0.074 12.7 0.0 1.8 1 0 0 1 1 1 0 MNLL subunit ANAPC1 PF12859.7 KNE01170.1 - 5.1e-11 43.2 0.1 1.9e-10 41.4 0.1 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KNE01170.1 - 1.2 9.7 6.5 17 6.0 0.2 4.6 4 0 0 4 4 4 0 Proteasome/cyclosome repeat GTP_EFTU PF00009.27 KNE01171.1 - 2.4e-58 196.9 0.1 3.2e-58 196.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KNE01171.1 - 6.4e-25 87.6 0.0 1.4e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KNE01171.1 - 1.7e-19 69.9 1.8 1.7e-19 69.9 1.8 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KNE01171.1 - 3.4e-05 23.9 0.0 5.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 KNE01171.1 - 0.017 14.7 1.1 0.021 14.4 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KNE01171.1 - 0.021 14.7 0.0 0.046 13.6 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 KNE01171.1 - 0.095 12.4 0.6 13 5.5 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Bul1_N PF04425.12 KNE01172.1 - 1e-77 261.8 0.7 3e-68 230.6 0.0 2.3 1 1 1 2 2 2 2 Bul1 N terminus Bul1_C PF04426.12 KNE01172.1 - 1.8e-17 63.7 0.5 1.6e-08 34.3 0.0 2.7 1 1 1 2 2 2 2 Bul1 C terminus INCENP_ARK-bind PF03941.15 KNE01174.1 - 1.8e-11 43.8 0.2 5.8e-11 42.2 0.2 2.0 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region TPR_1 PF00515.28 KNE01175.1 - 1.7e-12 46.6 14.8 1.6e-05 24.5 1.7 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KNE01175.1 - 7e-12 44.5 6.7 0.0053 16.8 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KNE01175.1 - 2.2e-05 24.9 0.4 0.0029 18.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KNE01175.1 - 3.2e-05 23.8 9.8 0.33 11.3 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KNE01175.1 - 4.7e-05 23.1 0.1 0.036 14.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KNE01175.1 - 0.0003 21.0 7.3 0.12 12.7 1.0 3.1 3 1 0 3 3 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KNE01175.1 - 0.0014 18.7 4.1 2.7 8.1 0.0 3.5 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 KNE01175.1 - 0.0019 18.4 4.0 0.0076 16.5 2.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KNE01175.1 - 0.021 14.5 2.0 4.4 7.1 0.1 3.2 2 1 1 3 3 3 0 TPR repeat DUF3808 PF10300.9 KNE01175.1 - 0.024 13.4 1.5 0.033 12.9 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) DUF4840 PF16128.5 KNE01175.1 - 0.053 13.6 1.7 3 7.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4840) Pox_T4_N PF04491.12 KNE01175.1 - 0.073 12.9 0.2 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Poxvirus T4 protein, N terminus Bul1_N PF04425.12 KNE01176.1 - 3.4e-86 289.8 0.1 1.1e-85 288.1 0.1 1.7 1 1 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.12 KNE01176.1 - 6.7e-24 84.7 2.7 3.6e-22 79.0 2.7 2.5 1 1 0 1 1 1 1 Bul1 C terminus G_glu_transpept PF01019.21 KNE01177.1 - 8.9e-137 456.9 0.0 1.1e-136 456.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Carn_acyltransf PF00755.20 KNE01178.1 - 9.8e-209 694.8 0.0 1.2e-208 694.5 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF1708 PF08101.11 KNE01179.1 - 1.4e-121 406.7 4.7 1.2e-119 400.3 4.7 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) bZIP_1 PF00170.21 KNE01180.1 - 3.1e-06 27.2 7.4 3.1e-06 27.2 7.4 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KNE01180.1 - 0.0001 22.3 9.6 0.0001 22.3 9.6 2.5 1 1 1 2 2 2 1 Basic region leucine zipper Aft1_HRA PF11786.8 KNE01180.1 - 0.00092 19.5 1.5 0.00092 19.5 1.5 3.0 2 1 0 2 2 2 1 Aft1 HRA domain DUF3584 PF12128.8 KNE01180.1 - 0.012 13.1 3.9 0.015 12.8 3.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FAM76 PF16046.5 KNE01180.1 - 0.065 12.6 9.1 0.096 12.0 9.1 1.2 1 0 0 1 1 1 0 FAM76 protein RNA_pol_Rpc4 PF05132.14 KNE01180.1 - 0.4 11.1 13.7 5.5 7.4 8.6 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 Phlebovirus_NSM PF07246.11 KNE01180.1 - 1.4 8.2 6.3 2 7.7 6.3 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M FancD2 PF14631.6 KNE01180.1 - 1.7 5.9 6.5 2.2 5.6 6.5 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease RR_TM4-6 PF06459.12 KNE01180.1 - 3.2 7.5 14.4 4.8 6.9 14.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glyco_hydro_47 PF01532.20 KNE01182.1 - 1.5e-167 558.2 0.2 1.7e-167 557.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 CEP76-C2 PF15627.6 KNE01183.1 - 0.12 11.9 0.0 0.15 11.7 0.0 1.0 1 0 0 1 1 1 0 CEP76 C2 domain ZapB PF06005.12 KNE01184.1 - 0.00022 21.6 1.4 0.00067 20.0 1.4 1.8 1 0 0 1 1 1 1 Cell division protein ZapB TSC22 PF01166.18 KNE01184.1 - 0.00034 20.9 0.6 0.001 19.3 0.6 1.8 1 0 0 1 1 1 1 TSC-22/dip/bun family Zn_clus PF00172.18 KNE01184.1 - 0.00055 20.0 8.2 0.00097 19.2 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4407 PF14362.6 KNE01184.1 - 0.0011 18.4 2.2 0.0017 17.8 2.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) FlxA PF14282.6 KNE01184.1 - 0.0012 18.8 8.3 0.0025 17.8 8.3 1.5 1 0 0 1 1 1 1 FlxA-like protein SlyX PF04102.12 KNE01184.1 - 0.0013 19.3 8.2 0.0042 17.7 8.2 1.9 1 0 0 1 1 1 1 SlyX RasGAP_C PF03836.15 KNE01184.1 - 0.014 15.5 0.2 0.078 13.1 0.1 2.1 2 0 0 2 2 2 0 RasGAP C-terminus DUF4140 PF13600.6 KNE01184.1 - 0.015 15.7 3.1 0.036 14.5 3.1 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4349 PF14257.6 KNE01184.1 - 0.017 14.6 0.9 0.028 13.9 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Spc24 PF08286.11 KNE01184.1 - 0.018 15.3 1.4 0.046 14.0 0.4 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Trimer_CC PF08954.11 KNE01184.1 - 0.022 14.3 4.7 0.15 11.7 5.8 1.8 2 0 0 2 2 1 0 Trimerisation motif YlqD PF11068.8 KNE01184.1 - 0.024 15.0 3.1 0.048 14.0 3.1 1.4 1 0 0 1 1 1 0 YlqD protein BBS2_C PF14782.6 KNE01184.1 - 0.063 12.0 0.1 0.095 11.4 0.1 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Uso1_p115_C PF04871.13 KNE01184.1 - 0.081 13.3 2.1 0.16 12.3 2.1 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Ribosomal_L29 PF00831.23 KNE01184.1 - 0.13 12.3 4.7 0.38 10.8 4.7 1.8 1 0 0 1 1 1 0 Ribosomal L29 protein Prefoldin PF02996.17 KNE01184.1 - 0.19 11.6 5.9 0.45 10.4 5.9 1.6 1 0 0 1 1 1 0 Prefoldin subunit Macoilin PF09726.9 KNE01184.1 - 0.2 10.1 2.0 0.32 9.5 2.0 1.2 1 0 0 1 1 1 0 Macoilin family Seryl_tRNA_N PF02403.22 KNE01184.1 - 0.21 11.9 2.4 0.55 10.5 2.4 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain IFP_35_N PF07334.13 KNE01184.1 - 0.29 11.3 4.0 0.76 9.9 4.0 1.8 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus GrpE PF01025.19 KNE01184.1 - 0.31 10.7 5.4 0.65 9.6 5.4 1.5 1 0 0 1 1 1 0 GrpE Med9 PF07544.13 KNE01184.1 - 0.39 10.8 4.4 0.9 9.7 4.4 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Cep57_MT_bd PF06657.13 KNE01184.1 - 0.4 11.2 3.8 1.1 9.8 3.8 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 CCDC-167 PF15188.6 KNE01184.1 - 0.48 10.8 2.8 0.58 10.5 1.0 2.1 2 0 0 2 2 1 0 Coiled-coil domain-containing protein 167 Spc7 PF08317.11 KNE01184.1 - 0.52 9.1 4.5 1 8.1 4.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Myosin_tail_1 PF01576.19 KNE01184.1 - 0.59 7.9 4.9 0.87 7.3 4.9 1.1 1 0 0 1 1 1 0 Myosin tail HalX PF08663.10 KNE01184.1 - 0.71 10.2 3.5 1.7 9.0 3.5 1.6 1 0 0 1 1 1 0 HalX domain TolA_bind_tri PF16331.5 KNE01184.1 - 1.1 9.4 12.2 2.5 8.2 12.2 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation Flg_hook PF02120.16 KNE01184.1 - 1.4 8.8 6.3 2.6 8.0 6.3 1.4 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Swi5 PF07061.11 KNE01184.1 - 1.9 8.7 4.7 1 9.5 2.1 1.8 2 0 0 2 2 1 0 Swi5 LPP PF04728.13 KNE01184.1 - 2.4 8.6 6.6 6.6 7.2 6.6 1.7 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Plasmid_RAQPRD PF09686.10 KNE01184.1 - 4 7.7 6.8 6.3 7.1 5.1 2.2 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DivIC PF04977.15 KNE01184.1 - 8.1 6.3 9.0 24 4.8 9.0 1.8 1 0 0 1 1 1 0 Septum formation initiator Cyt-b5 PF00173.28 KNE01185.1 - 1.1e-10 41.5 0.0 1.5e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cys_Met_Meta_PP PF01053.20 KNE01186.1 - 5.3e-36 124.0 0.0 7.1e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KNE01186.1 - 6.9e-06 25.5 0.0 1.4e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II HMG-CoA_red PF00368.18 KNE01187.1 - 3.4e-142 473.8 0.6 4.7e-142 473.4 0.6 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 KNE01187.1 - 4.5e-11 42.8 9.2 4.5e-11 42.8 9.2 1.9 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation HPIH PF13323.6 KNE01187.1 - 5.3e-11 42.6 5.0 9.3e-10 38.6 1.1 3.3 2 1 0 2 2 2 1 N-terminal domain with HPIH motif DUF4282 PF14110.6 KNE01187.1 - 1.5 9.6 7.0 0.52 11.1 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Imm25 PF15564.6 KNE01189.1 - 0.013 15.4 0.2 3.8 7.5 0.0 2.7 2 1 1 3 3 3 0 Immunity protein 25 NPV_P10 PF05531.12 KNE01189.1 - 0.18 12.3 3.7 2.7 8.5 0.2 3.1 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Tubulin PF00091.25 KNE01191.1 - 6e-54 183.2 0.1 1.5e-53 182.0 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KNE01191.1 - 1.3e-13 51.2 0.0 2.5e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 KNE01191.1 - 0.13 11.4 0.0 0.27 10.4 0.0 1.6 2 0 0 2 2 2 0 Tubulin like Aminotran_1_2 PF00155.21 KNE01192.1 - 4.2e-23 82.1 0.0 5.2e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II BAR_2 PF10455.9 KNE01193.1 - 1e-62 211.9 7.9 1.5e-62 211.3 7.9 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KNE01193.1 - 1.9e-14 53.9 6.0 6.3e-14 52.2 6.0 1.8 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 KNE01193.1 - 0.0038 17.0 10.7 0.0051 16.5 2.6 2.2 2 0 0 2 2 2 1 BAR domain of APPL family Arfaptin PF06456.13 KNE01193.1 - 0.031 13.8 2.8 0.22 11.0 0.1 2.8 2 1 0 2 2 2 0 Arfaptin-like domain Transcrip_act PF04949.13 KNE01193.1 - 0.15 12.0 3.0 0.14 12.1 0.6 2.1 2 0 0 2 2 2 0 Transcriptional activator Frataxin_Cyay PF01491.16 KNE01193.1 - 0.18 11.9 1.6 6.8 6.8 0.1 3.2 3 0 0 3 3 3 0 Frataxin-like domain Plk4_PB2 PF18409.1 KNE01193.1 - 0.37 11.5 3.2 26 5.5 0.0 3.0 2 2 1 3 3 3 0 Polo-like Kinase 4 Polo Box 2 T3SS_basalb_I PF17001.5 KNE01193.1 - 0.44 11.2 5.8 0.93 10.1 0.8 3.2 2 2 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI DUF148 PF02520.17 KNE01193.1 - 1.2 9.3 7.8 0.35 11.0 1.1 3.4 3 2 0 3 3 3 0 Domain of unknown function DUF148 Csm2_III-A PF03750.13 KNE01193.1 - 1.2 10.0 6.4 2.3 9.1 1.4 3.0 2 1 0 2 2 2 0 Csm2 Type III-A Fib_alpha PF08702.10 KNE01193.1 - 1.3 9.2 11.1 0.51 10.5 1.9 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family ApoLp-III PF07464.11 KNE01193.1 - 1.6 8.8 13.9 0.73 9.9 2.1 3.8 2 2 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) WEMBL PF05701.11 KNE01193.1 - 1.8 7.1 11.5 2.1 7.0 1.1 2.1 2 0 0 2 2 2 0 Weak chloroplast movement under blue light TMPIT PF07851.13 KNE01193.1 - 2 7.6 6.3 4.1 6.6 0.3 2.2 2 0 0 2 2 2 0 TMPIT-like protein AA_kinase PF00696.28 KNE01194.1 - 1e-42 146.4 1.2 1.4e-42 146.0 0.1 1.7 2 1 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 KNE01194.1 - 1.3e-10 40.8 1.1 0.00034 20.3 0.0 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 KNE01194.1 - 2.8e-06 27.0 2.2 0.00012 21.8 0.6 2.5 2 0 0 2 2 2 2 ACT domain PDEase_I PF00233.19 KNE01194.1 - 0.11 12.2 2.4 3.7 7.2 0.1 2.3 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase Ofd1_CTDD PF10637.9 KNE01196.1 - 5.4e-91 304.5 1.0 3.3e-89 298.6 0.0 2.8 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KNE01196.1 - 3.1e-25 88.7 0.0 1.2e-24 86.8 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KNE01196.1 - 3e-13 50.5 0.0 5.7e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NAD_binding_1 PF00175.21 KNE01197.1 - 3.5e-32 111.3 0.0 6.4e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KNE01197.1 - 1.1e-30 105.8 0.0 2e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KNE01197.1 - 1e-06 29.0 0.0 0.00021 21.4 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain DUF2080 PF09853.9 KNE01198.1 - 0.035 13.8 0.2 0.066 13.0 0.0 1.5 2 0 0 2 2 2 0 Putative transposon-encoded protein (DUF2080) Vps62 PF06101.11 KNE01199.1 - 4.4e-11 41.8 5.7 1.2e-10 40.4 4.3 2.2 2 1 1 3 3 3 1 Vacuolar protein sorting-associated protein 62 AA_permease PF00324.21 KNE01201.1 - 6.7e-140 466.9 42.7 7.6e-140 466.7 42.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KNE01201.1 - 5.3e-40 137.6 45.0 6.1e-40 137.3 45.0 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3384 PF11864.8 KNE01202.1 - 1.2e-71 242.1 16.6 2.1e-71 241.3 16.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 KNE01202.1 - 1.7e-44 151.6 2.0 3.2e-44 150.7 2.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KNE01202.1 - 3.1e-19 69.3 2.8 3.7e-19 69.0 0.7 2.1 2 0 0 2 2 2 1 Tuberin DUF4619 PF15398.6 KNE01203.1 - 0.19 11.2 0.0 0.26 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) SIS PF01380.22 KNE01204.1 - 2.8e-12 46.6 0.0 5.1e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 KNE01204.1 - 0.00065 19.7 0.0 0.0057 16.7 0.0 2.3 1 1 1 2 2 2 1 SIS domain PUF PF00806.19 KNE01206.1 - 5.8e-59 192.6 14.9 1.9e-08 33.5 0.2 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat THP2 PF09432.10 KNE01206.1 - 0.0036 17.4 0.4 0.0096 16.0 0.4 1.7 1 0 0 1 1 1 1 Tho complex subunit THP2 BRAP2 PF07576.12 KNE01207.1 - 0.037 14.2 0.0 0.087 13.0 0.0 1.6 1 0 0 1 1 1 0 BRCA1-associated protein 2 ANAPC4_WD40 PF12894.7 KNE01208.1 - 3.4e-05 24.1 0.1 0.26 11.6 0.0 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KNE01208.1 - 0.0011 19.7 1.9 0.57 11.1 0.0 4.0 5 0 0 5 5 5 2 WD domain, G-beta repeat TPR_2 PF07719.17 KNE01209.1 - 3.2e-33 111.1 21.2 3.5e-05 23.6 0.3 10.9 11 0 0 11 11 10 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KNE01209.1 - 1.4e-27 95.7 19.3 7.3e-22 77.4 0.0 6.3 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KNE01209.1 - 3.1e-27 93.2 25.5 1.1e-06 28.1 1.3 10.4 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 KNE01209.1 - 6.2e-19 66.6 15.4 5.4e-05 23.1 0.4 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 KNE01209.1 - 1.2e-16 60.7 13.7 5.4e-10 39.4 2.0 8.7 5 2 3 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 KNE01209.1 - 4.6e-16 58.1 13.3 0.22 12.4 0.0 10.3 9 2 3 12 12 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 KNE01209.1 - 5.7e-16 58.8 11.0 0.73 10.4 0.1 8.6 5 3 3 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 KNE01209.1 - 4.8e-15 55.9 10.6 0.00052 20.6 0.0 8.2 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 KNE01209.1 - 2.9e-12 45.7 9.0 0.005 16.8 0.1 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 KNE01209.1 - 4.4e-11 42.4 11.6 0.13 12.7 0.0 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_10 PF13374.6 KNE01209.1 - 2.1e-09 36.9 14.7 0.0044 16.9 0.9 7.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 KNE01209.1 - 5.9e-09 36.0 11.8 0.44 11.3 0.3 8.2 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 KNE01209.1 - 4.8e-08 32.6 1.8 0.37 10.0 0.0 4.6 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 KNE01209.1 - 9.6e-07 28.9 1.3 0.081 13.1 0.0 5.3 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KNE01209.1 - 1.7e-06 27.6 13.7 0.0017 18.0 0.1 6.6 7 1 1 8 8 7 2 TPR repeat TPR_MalT PF17874.1 KNE01209.1 - 0.00015 21.3 3.8 0.0089 15.4 1.6 3.8 3 2 0 3 3 3 1 MalT-like TPR region Coatomer_E PF04733.14 KNE01209.1 - 0.00083 18.9 1.3 0.076 12.4 0.2 3.5 4 0 0 4 4 4 1 Coatomer epsilon subunit TPR_21 PF09976.9 KNE01209.1 - 0.0014 18.4 1.5 0.22 11.2 0.2 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat-like domain Fis1_TPR_C PF14853.6 KNE01209.1 - 0.043 13.9 6.8 42 4.3 0.0 5.6 5 1 1 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.7 KNE01209.1 - 0.043 13.9 0.3 5.6 7.0 0.0 3.2 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) MIT PF04212.18 KNE01209.1 - 0.16 12.0 5.5 14 5.8 0.1 4.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 KNE01209.1 - 0.71 9.9 0.0 0.71 9.9 0.0 5.6 8 0 0 8 8 6 0 Tetratricopeptide repeat WD40 PF00400.32 KNE01210.1 - 2.3e-23 82.0 2.1 5.7e-07 30.1 0.1 5.7 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNE01210.1 - 1.8e-06 28.1 1.7 0.021 15.1 0.2 4.0 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KNE01210.1 - 8.9e-05 21.6 0.3 0.0018 17.3 0.0 2.8 2 2 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 KNE01210.1 - 8.9e-05 21.3 0.2 0.11 11.1 0.0 2.7 3 0 0 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KNE01210.1 - 0.00021 21.3 1.2 3.6 7.7 0.0 4.5 4 1 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.11 KNE01210.1 - 0.0032 16.3 2.6 8.7 5.0 0.1 3.8 2 1 3 5 5 5 3 Nup133 N terminal like AlaDh_PNT_N PF05222.15 KNE01211.1 - 1.8e-29 102.8 0.0 2.5e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain FGGY_N PF00370.21 KNE01213.1 - 4e-14 52.8 0.0 1.4e-09 37.9 0.0 3.5 2 2 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KNE01213.1 - 9.9e-12 45.0 0.1 3.1e-10 40.1 0.1 2.8 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain SPC12 PF06645.13 KNE01214.1 - 4.4e-23 81.2 3.1 5e-23 81.0 3.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) LAX PF15681.5 KNE01214.1 - 0.089 11.6 2.8 0.1 11.4 2.8 1.3 1 1 0 1 1 1 0 Lymphocyte activation family X E1-E2_ATPase PF00122.20 KNE01214.1 - 0.16 11.4 2.4 2.2 7.7 3.8 1.8 1 1 1 2 2 2 0 E1-E2 ATPase VirB3 PF05101.13 KNE01214.1 - 7.8 6.8 8.9 11 6.4 8.9 1.2 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Hap4_Hap_bind PF10297.9 KNE01216.1 - 8.6e-05 22.5 5.1 0.00023 21.2 5.1 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 Aldedh PF00171.22 KNE01218.1 - 6.8e-135 450.1 0.1 7.8e-135 450.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family hDGE_amylase PF14701.6 KNE01219.1 - 2e-168 561.0 0.0 2.8e-168 560.6 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KNE01219.1 - 3.4e-122 408.1 0.0 6.9e-122 407.1 0.0 1.5 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KNE01219.1 - 4.2e-80 269.1 0.0 6.7e-80 268.4 0.0 1.3 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KNE01219.1 - 5.2e-22 77.8 0.1 1e-21 76.9 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 KNE01219.1 - 6.4e-05 22.7 0.1 0.00022 20.9 0.1 1.8 2 0 0 2 2 2 1 Alpha amylase, catalytic domain GST_C_2 PF13410.6 KNE01220.1 - 2.8e-09 36.9 0.0 9e-09 35.2 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KNE01220.1 - 1.3e-05 25.3 0.5 2.6e-05 24.3 0.4 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KNE01220.1 - 1.5e-05 25.2 0.3 2.8e-05 24.2 0.3 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ssDNA_DBD PF18333.1 KNE01220.1 - 0.07 13.2 2.3 1.8 8.7 0.2 2.8 2 1 0 3 3 3 0 Non-canonical single-stranded DNA-binding domain TIP120 PF08623.10 KNE01220.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) Sugar_tr PF00083.24 KNE01222.1 - 6.8e-32 110.9 35.7 2.4e-20 72.9 12.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KNE01222.1 - 2.5e-22 79.3 40.9 3.2e-11 42.8 16.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Transgly_assoc PF04226.13 KNE01222.1 - 0.41 10.9 0.1 0.41 10.9 0.1 4.0 4 1 1 5 5 5 0 Transglycosylase associated protein THOC2_N PF16134.5 KNE01223.1 - 3.5e-157 524.8 4.4 3.5e-157 524.8 4.4 2.4 2 0 0 2 2 2 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KNE01223.1 - 1.8e-71 240.8 2.2 1.8e-71 240.8 2.2 2.6 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KNE01223.1 - 8.2e-26 89.9 0.6 1.2e-24 86.2 0.2 2.9 3 0 0 3 3 3 1 Transcription- and export-related complex subunit zf-C2H2 PF00096.26 KNE01224.1 - 9.2e-23 79.4 63.4 0.00017 21.9 2.7 8.3 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KNE01224.1 - 9.9e-14 50.9 61.0 0.012 16.4 1.6 8.4 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KNE01224.1 - 6.8e-06 26.2 37.0 0.0044 17.3 1.9 7.4 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KNE01224.1 - 0.0041 17.5 0.2 0.0041 17.5 0.2 8.5 8 1 1 9 9 9 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 KNE01224.1 - 0.027 14.5 0.5 0.027 14.5 0.5 6.5 7 0 0 7 7 7 0 C2H2-type zinc finger zf-met PF12874.7 KNE01224.1 - 0.07 13.6 29.4 3.8 8.0 0.2 7.7 8 0 0 8 8 8 0 Zinc-finger of C2H2 type Myb_DNA-binding PF00249.31 KNE01225.1 - 3.7e-25 87.8 0.9 4.5e-11 42.8 0.2 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KNE01225.1 - 4.6e-21 74.8 2.7 2.6e-12 46.8 0.5 3.1 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 KNE01225.1 - 0.011 15.8 7.2 5.2 7.1 0.0 5.1 4 1 1 5 5 5 0 SLIDE HBS1_N PF08938.10 KNE01225.1 - 0.043 14.1 2.0 0.3 11.4 2.0 2.5 1 0 0 1 1 1 0 HBS1 N-terminus LppA PF16708.5 KNE01225.1 - 0.68 9.9 3.2 4.7 7.1 0.2 3.0 3 0 0 3 3 3 0 Lipoprotein confined to pathogenic Mycobacterium BRO1 PF03097.18 KNE01226.1 - 1.7e-86 290.5 0.5 1.7e-86 290.5 0.5 2.2 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KNE01226.1 - 2.7e-57 194.3 11.3 7.2e-57 192.9 11.3 1.8 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Spc29 PF17082.5 KNE01226.1 - 0.072 12.9 5.9 0.049 13.5 2.9 2.2 2 0 0 2 2 2 0 Spindle Pole Component 29 Talin_middle PF09141.10 KNE01226.1 - 0.09 12.8 0.2 0.57 10.2 0.1 2.4 2 0 0 2 2 2 0 Talin, middle domain TcpS PF17456.2 KNE01226.1 - 0.15 12.1 5.4 1.1 9.3 2.4 2.8 2 0 0 2 2 2 0 Toxin-coregulated pilus protein S Methyltrn_RNA_2 PF04013.12 KNE01226.1 - 0.17 11.5 1.4 0.41 10.3 0.7 1.8 1 1 1 2 2 2 0 Putative SAM-dependent RNA methyltransferase PRESAN PF09687.10 KNE01226.1 - 1.4 9.5 9.1 2.2 8.9 1.1 3.4 2 1 1 3 3 3 0 Plasmodium RESA N-terminal IPPT PF01715.17 KNE01227.1 - 2.6e-64 217.2 0.2 2.6e-64 217.2 0.2 1.6 2 0 0 2 2 2 1 IPP transferase AAA_18 PF13238.6 KNE01227.1 - 0.014 15.9 0.1 0.014 15.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain DUF1752 PF08550.10 KNE01231.1 - 5.7e-11 42.1 5.3 5.7e-11 42.1 5.3 1.8 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) STIMATE PF12400.8 KNE01232.1 - 1.9e-35 122.1 7.0 1.9e-35 122.1 7.0 1.6 2 0 0 2 2 2 1 STIMATE family COX17 PF05051.13 KNE01233.1 - 1.9e-22 79.3 6.3 2.2e-22 79.1 6.3 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.13 KNE01233.1 - 0.00047 20.2 1.0 0.00078 19.5 1.0 1.5 1 1 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 KNE01233.1 - 0.0069 16.4 3.6 0.01 15.9 0.1 2.1 1 1 1 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like Vps54 PF07928.12 KNE01234.1 - 7.8e-32 110.5 0.7 7.8e-32 110.5 0.7 3.0 3 0 0 3 3 3 1 Vps54-like protein Vps54_N PF10475.9 KNE01234.1 - 0.00042 19.7 0.5 0.00042 19.7 0.5 2.7 2 1 1 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex MTBP_C PF14920.6 KNE01234.1 - 0.1 12.3 5.4 0.24 11.1 5.4 1.6 1 0 0 1 1 1 0 MDM2-binding DIOX_N PF14226.6 KNE01235.1 - 1.1e-29 103.5 0.0 3.3e-29 102.0 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KNE01235.1 - 9e-17 61.4 0.0 1.9e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SMBP PF16785.5 KNE01236.1 - 0.089 13.0 0.7 0.57 10.4 0.1 2.3 2 0 0 2 2 2 0 Small metal-binding protein Speriolin_N PF15058.6 KNE01236.1 - 0.093 12.8 0.3 0.093 12.8 0.3 1.9 2 0 0 2 2 2 0 Speriolin N terminus Mito_carr PF00153.27 KNE01237.1 - 2.5e-46 155.5 4.8 4.3e-16 58.6 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HATPase_c_3 PF13589.6 KNE01238.1 - 3.5e-13 49.6 0.0 6.4e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 KNE01238.1 - 2.9e-12 46.6 0.0 1e-11 44.8 0.0 1.9 1 1 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 KNE01238.1 - 2e-08 34.7 0.0 7.2e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NPCC PF08058.11 KNE01239.1 - 2e-27 95.8 0.3 4.5e-27 94.7 0.0 1.7 2 0 0 2 2 2 1 Nuclear pore complex component CBP_BcsF PF11120.8 KNE01239.1 - 0.044 13.9 2.8 0.64 10.2 0.1 2.6 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF 4HBT_3 PF13622.6 KNE01240.1 - 2.2e-33 116.5 0.0 2.8e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KNE01240.1 - 5.4e-10 39.2 2.8 3.6e-05 23.6 0.2 3.6 3 1 0 3 3 3 2 Acyl-CoA thioesterase DUF4230 PF14014.6 KNE01240.1 - 0.17 12.2 0.0 0.48 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4230) 4HBT_3 PF13622.6 KNE01241.1 - 1.4e-30 107.4 0.0 1.9e-30 106.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KNE01241.1 - 4.7e-08 32.9 0.3 3.4e-06 26.9 0.2 2.8 2 1 0 2 2 2 1 Acyl-CoA thioesterase Peptidase_C92 PF05708.12 KNE01241.1 - 0.11 12.6 0.0 0.95 9.5 0.0 2.1 2 0 0 2 2 2 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 4HBT_3 PF13622.6 KNE01243.1 - 4.9e-35 122.0 0.0 7.1e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KNE01243.1 - 4.6e-12 45.9 0.6 2.8e-06 27.2 0.1 2.5 2 0 0 2 2 2 2 Acyl-CoA thioesterase Sec1 PF00995.23 KNE01244.1 - 1.3e-54 186.4 11.7 1.6e-54 186.1 11.7 1.0 1 0 0 1 1 1 1 Sec1 family COX7C PF02935.16 KNE01247.1 - 7.2e-17 61.4 5.6 7.8e-17 61.3 5.6 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc CTD_bind PF04818.13 KNE01249.1 - 0.0045 17.8 0.1 0.012 16.5 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. VHS PF00790.19 KNE01249.1 - 0.032 14.1 0.5 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 VHS domain Iso_dh PF00180.20 KNE01251.1 - 2e-73 247.6 0.0 2.3e-73 247.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase IDH PF03971.14 KNE01251.1 - 0.097 11.1 0.2 0.34 9.3 0.0 1.7 2 0 0 2 2 2 0 Monomeric isocitrate dehydrogenase COG6 PF06419.11 KNE01259.1 - 5.5e-134 447.7 24.9 7.4e-134 447.3 24.9 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Fmp27_WPPW PF10359.9 KNE01259.1 - 0.0015 17.5 2.9 0.086 11.7 2.9 2.2 1 1 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain YaeQ PF07152.12 KNE01259.1 - 0.073 12.7 0.5 0.22 11.1 0.1 2.0 2 1 0 2 2 2 0 YaeQ protein zf-CCCH_7 PF18586.1 KNE01259.1 - 1.2 9.5 7.0 2.7 8.4 0.0 4.1 3 2 1 5 5 5 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Diphthamide_syn PF01866.17 KNE01261.1 - 3.1e-116 388.1 0.0 3.7e-116 387.8 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein SHQ1 PF04925.15 KNE01262.1 - 4.8e-71 237.9 2.3 6.5e-71 237.5 2.3 1.2 1 0 0 1 1 1 1 SHQ1 protein DUF2722 PF10846.8 KNE01263.1 - 3.6e-83 280.1 33.9 1.1e-81 275.2 33.9 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2722) Dendrin PF15498.6 KNE01264.1 - 0.21 10.3 1.5 0.3 9.7 1.5 1.1 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin LMBR1 PF04791.16 KNE01265.1 - 6.8e-68 229.8 29.8 7.9e-68 229.6 29.8 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF4014 PF13198.6 KNE01265.1 - 0.36 11.2 4.7 5.2 7.5 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) ABC_tran PF00005.27 KNE01266.1 - 4.9e-44 150.2 5.0 4.1e-21 75.9 0.1 3.2 4 0 0 4 4 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KNE01266.1 - 7.2e-21 74.0 3.8 7.2e-21 74.0 3.8 3.7 4 0 0 4 4 4 1 ABC transporter AAA_21 PF13304.6 KNE01266.1 - 3.6e-15 56.6 14.0 0.0018 18.2 0.0 5.5 3 2 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KNE01266.1 - 7.4e-09 35.4 1.0 0.00099 18.6 0.0 3.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 KNE01266.1 - 1.2e-05 25.6 2.5 0.08 13.2 0.5 3.3 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KNE01266.1 - 1.2e-05 25.3 0.0 0.1 12.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KNE01266.1 - 1.6e-05 24.5 0.6 0.17 11.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KNE01266.1 - 2.4e-05 24.6 0.9 0.3 11.3 0.2 3.5 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.6 KNE01266.1 - 6.9e-05 23.0 1.0 0.27 11.4 0.1 3.4 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KNE01266.1 - 0.00011 22.7 0.6 0.11 12.9 0.0 3.0 3 0 0 3 3 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 KNE01266.1 - 0.00013 22.0 0.0 0.11 12.6 0.0 3.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KNE01266.1 - 0.00013 22.5 1.6 0.22 12.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 KNE01266.1 - 0.0002 21.8 0.9 0.68 10.4 0.1 4.2 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KNE01266.1 - 0.00028 20.7 0.1 0.41 10.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KNE01266.1 - 0.0005 20.6 27.7 0.14 12.6 0.0 5.2 5 0 0 5 5 5 2 AAA domain AAA_30 PF13604.6 KNE01266.1 - 0.00093 19.0 0.0 0.86 9.3 0.0 3.6 3 1 0 3 3 3 1 AAA domain NACHT PF05729.12 KNE01266.1 - 0.0026 17.7 0.8 0.83 9.6 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_7 PF12775.7 KNE01266.1 - 0.0031 17.1 0.1 0.84 9.1 0.1 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_15 PF13175.6 KNE01266.1 - 0.0034 17.1 21.4 0.15 11.8 0.1 4.4 4 1 0 4 4 4 2 AAA ATPase domain RNA_helicase PF00910.22 KNE01266.1 - 0.0051 17.2 0.0 6.6 7.2 0.0 2.9 2 0 0 2 2 2 0 RNA helicase PduV-EutP PF10662.9 KNE01266.1 - 0.0074 16.0 0.3 2.7 7.7 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.25 KNE01266.1 - 0.014 15.1 0.0 0.15 11.6 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain T2SSE PF00437.20 KNE01266.1 - 0.015 14.3 0.0 0.14 11.2 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein MobB PF03205.14 KNE01266.1 - 0.017 15.0 0.1 0.46 10.4 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 KNE01266.1 - 0.019 15.0 1.1 1.4 9.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 KNE01266.1 - 0.027 14.5 9.1 0.036 14.1 0.1 3.5 3 1 1 4 4 4 0 Dynamin family Roc PF08477.13 KNE01266.1 - 0.029 14.6 0.1 4.3 7.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 KNE01266.1 - 0.091 12.8 0.3 8.4 6.4 0.1 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KNE01266.1 - 0.093 12.7 0.2 3.2 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MeaB PF03308.16 KNE01266.1 - 0.1 11.5 0.1 1.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Pox_A32 PF04665.12 KNE01266.1 - 0.11 12.0 2.1 0.73 9.3 0.1 2.7 3 0 0 3 3 3 0 Poxvirus A32 protein MCU PF04678.13 KNE01266.1 - 2.3 8.3 6.0 11 6.1 0.0 3.1 3 0 0 3 3 3 0 Mitochondrial calcium uniporter Lactamase_B_2 PF12706.7 KNE01267.1 - 1.7e-30 106.0 0.0 2.9e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KNE01267.1 - 3.3e-16 59.6 0.0 4.9e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Romo1 PF10247.9 KNE01268.1 - 6.9e-28 96.8 13.5 9.4e-28 96.4 13.5 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 DUF1690 PF07956.11 KNE01269.1 - 1.2e-40 139.1 10.8 1.4e-40 138.9 10.8 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) YqgF PF14639.6 KNE01269.1 - 0.012 15.4 1.4 0.015 15.0 1.4 1.2 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 ATP-synt_B PF00430.18 KNE01269.1 - 0.043 13.9 12.5 0.057 13.5 12.5 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Mem_trans PF03547.18 KNE01269.1 - 0.99 7.7 3.0 1.2 7.5 3.0 1.1 1 0 0 1 1 1 0 Membrane transport protein TnpV PF14198.6 KNE01269.1 - 1 9.4 6.4 1.5 8.9 4.8 1.9 1 1 1 2 2 2 0 Transposon-encoded protein TnpV MbeB_N PF04837.12 KNE01269.1 - 2.4 8.5 9.1 9.5 6.6 1.3 2.7 2 1 0 2 2 2 0 MbeB-like, N-term conserved region UCH PF00443.29 KNE01270.1 - 1e-44 153.0 3.5 1.4e-44 152.5 3.5 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KNE01270.1 - 9.1e-11 41.9 15.3 2.7e-08 33.8 15.3 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KNE01270.1 - 1e-09 38.0 0.1 2.9e-09 36.6 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin family Nop16 PF09420.10 KNE01270.1 - 0.033 14.2 2.2 0.074 13.1 2.2 1.5 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 ZYG-11_interact PF05884.12 KNE01270.1 - 0.67 9.3 2.1 1.2 8.5 2.1 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 Efg1 PF10153.9 KNE01270.1 - 3 8.2 8.8 34 4.8 8.8 2.3 1 1 0 1 1 1 0 rRNA-processing protein Efg1 Aldedh PF00171.22 KNE01271.1 - 2.7e-78 263.5 0.3 5.4e-78 262.5 0.0 1.6 2 0 0 2 2 2 1 Aldehyde dehydrogenase family LuxC PF05893.14 KNE01271.1 - 0.0054 15.8 0.0 0.0054 15.8 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) LIM_bind PF01803.16 KNE01271.1 - 0.046 13.2 0.2 0.077 12.5 0.2 1.2 1 0 0 1 1 1 0 LIM-domain binding protein BOP1NT PF08145.12 KNE01271.1 - 0.71 9.8 3.7 0.29 11.0 1.3 1.5 2 0 0 2 2 2 0 BOP1NT (NUC169) domain Abhydrolase_6 PF12697.7 KNE01272.1 - 0.00028 21.6 0.0 0.00034 21.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KNE01272.1 - 0.14 11.8 0.0 0.39 10.3 0.0 1.8 1 1 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 KNE01272.1 - 0.17 11.1 0.1 3.4 6.9 0.0 2.3 1 1 1 2 2 2 0 Serine aminopeptidase, S33 ANAPC4_WD40 PF12894.7 KNE01273.1 - 2.1e-06 27.9 0.1 0.018 15.3 0.0 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KNE01273.1 - 4.4e-05 24.1 0.1 0.66 11.0 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat RRN3 PF05327.11 KNE01274.1 - 9.2e-149 496.5 6.4 9.2e-149 496.5 6.4 2.0 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 DUF1539 PF07560.11 KNE01274.1 - 0.037 14.1 0.2 0.3 11.2 0.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) DUF5414 PF17435.2 KNE01274.1 - 0.06 13.0 0.3 0.097 12.3 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5414) UvrA_DNA-bind PF17755.1 KNE01274.1 - 0.079 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 UvrA DNA-binding domain Sigma70_ner PF04546.13 KNE01274.1 - 0.54 10.1 14.6 11 5.8 0.1 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF913 PF06025.12 KNE01274.1 - 5.7 5.8 7.8 7.7 5.4 0.2 2.9 2 1 1 3 3 3 0 Domain of Unknown Function (DUF913) JAB PF01398.21 KNE01275.1 - 0.017 15.1 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease BssB_TutG PF18512.1 KNE01277.1 - 0.11 12.4 0.6 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 Benzylsuccinate synthase beta subunit STE PF02200.16 KNE01278.1 - 1.5e-58 195.9 0.5 2.3e-58 195.3 0.5 1.3 1 0 0 1 1 1 1 STE like transcription factor CLASP_N PF12348.8 KNE01279.1 - 3.7e-77 258.9 16.2 4.3e-69 232.6 0.8 3.3 3 0 0 3 3 3 2 CLASP N terminal Peptidase_C13 PF01650.18 KNE01280.1 - 5.7e-44 150.5 0.5 9.7e-44 149.8 0.5 1.3 1 0 0 1 1 1 1 Peptidase C13 family ResIII PF04851.15 KNE01281.1 - 8.4e-29 100.8 0.1 2.1e-28 99.5 0.1 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KNE01281.1 - 1.4e-15 57.6 0.4 6.3e-15 55.5 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KNE01281.1 - 7.5e-10 38.9 1.8 1.7e-09 37.7 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KNE01281.1 - 0.0051 16.0 0.1 0.014 14.6 0.1 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_2 PF13307.6 KNE01281.1 - 0.0093 16.1 0.1 3.6 7.7 0.0 2.6 2 0 0 2 2 2 2 Helicase C-terminal domain DUF2075 PF09848.9 KNE01281.1 - 0.057 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Pol_alpha_B_N PF08418.10 KNE01282.1 - 6.6e-37 127.8 2.1 1.2e-36 127.0 1.3 1.8 2 0 0 2 2 2 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 KNE01282.1 - 8.5e-36 123.3 0.2 1.3e-35 122.7 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B La PF05383.17 KNE01283.1 - 2.8e-21 75.3 0.2 7.5e-21 74.0 0.0 1.8 2 0 0 2 2 2 1 La domain RRM_1 PF00076.22 KNE01283.1 - 0.012 15.4 0.6 0.16 11.8 0.6 2.3 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2201_N PF13203.6 KNE01283.1 - 0.027 14.1 0.0 0.051 13.2 0.0 1.4 1 1 0 1 1 1 0 Putative metallopeptidase domain Nre_N PF04894.12 KNE01283.1 - 0.13 12.1 0.2 0.27 11.0 0.0 1.5 2 0 0 2 2 2 0 Archaeal Nre, N-terminal Ala_racemase_N PF01168.20 KNE01284.1 - 5.3e-27 94.9 0.0 6.4e-27 94.6 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DHQS PF01959.16 KNE01284.1 - 0.039 12.9 0.1 0.089 11.7 0.0 1.6 2 0 0 2 2 2 0 3-dehydroquinate synthase II Anoctamin PF04547.12 KNE01285.1 - 4.8e-68 230.0 7.6 6.6e-68 229.6 7.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel SH3_9 PF14604.6 KNE01286.1 - 5.2e-11 42.2 0.4 1.4e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KNE01286.1 - 6.4e-11 41.7 0.9 1.4e-10 40.6 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KNE01286.1 - 9.8e-09 34.8 0.0 2.1e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DNApol_Exo PF18136.1 KNE01286.1 - 0.038 13.1 1.7 0.079 12.1 1.7 1.4 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain PolyA_pol PF01743.20 KNE01286.1 - 0.34 11.4 1.5 0.84 10.1 1.5 1.6 1 0 0 1 1 1 0 Poly A polymerase head domain SURF2 PF05477.11 KNE01286.1 - 0.48 10.1 19.0 1.3 8.6 19.0 1.7 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Atg14 PF10186.9 KNE01286.1 - 1.9 7.5 6.7 3.7 6.6 6.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3987 PF13148.6 KNE01286.1 - 2.1 7.3 7.7 4.5 6.2 7.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) WD40 PF00400.32 KNE01287.1 - 6.1e-13 49.0 10.5 9.4e-06 26.3 0.1 5.5 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNE01287.1 - 1.3e-08 35.0 0.0 0.023 15.0 0.0 4.4 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain CAP PF00188.26 KNE01289.1 - 1.9e-16 61.1 7.0 1.9e-16 61.1 7.0 2.7 2 1 0 2 2 2 1 Cysteine-rich secretory protein family Adaptin_N PF01602.20 KNE01290.1 - 3.7e-77 260.1 7.6 6.3e-76 256.0 7.6 2.0 1 1 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KNE01290.1 - 1.9e-06 28.1 0.0 5.1e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Cnd1 PF12717.7 KNE01290.1 - 0.032 14.3 0.1 6.5 6.8 0.0 2.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 RasGEF_N_2 PF14663.6 KNE01290.1 - 0.1 13.0 0.7 0.76 10.2 0.1 2.9 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Ric8 PF10165.9 KNE01290.1 - 0.12 11.4 1.4 0.27 10.2 0.8 1.8 2 0 0 2 2 2 0 Guanine nucleotide exchange factor synembryn TAF6_C PF07571.13 KNE01290.1 - 0.13 12.6 2.0 6 7.3 0.0 4.1 4 1 0 5 5 5 0 TAF6 C-terminal HEAT repeat domain HEAT_2 PF13646.6 KNE01290.1 - 0.14 12.6 0.1 1.8 9.0 0.0 2.9 2 0 0 2 2 2 0 HEAT repeats Mt_ATP-synt_D PF05873.12 KNE01291.1 - 2.8e-19 69.5 3.6 3.8e-19 69.1 3.6 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF4547 PF15080.6 KNE01291.1 - 0.03 14.0 0.5 0.1 12.2 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4547) MbeB_N PF04837.12 KNE01291.1 - 0.14 12.5 4.4 0.14 12.4 1.2 2.3 2 0 0 2 2 2 0 MbeB-like, N-term conserved region PSY3 PF16836.5 KNE01292.1 - 2e-11 43.8 0.1 2.4e-11 43.6 0.1 1.1 1 0 0 1 1 1 1 Shu complex component Psy3, DNA-binding description Phage_hub_GP28 PF11110.8 KNE01292.1 - 0.067 13.1 0.1 0.098 12.6 0.1 1.3 1 0 0 1 1 1 0 Baseplate hub distal subunit F-box_4 PF15966.5 KNE01293.1 - 0.0049 16.7 0.0 0.27 11.1 0.0 2.5 2 0 0 2 2 2 1 F-box SMC_hinge PF06470.13 KNE01293.1 - 0.014 15.7 0.0 0.046 14.0 0.0 1.9 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain MIF4G_like PF09088.11 KNE01293.1 - 0.033 14.0 0.3 0.76 9.5 0.0 2.4 2 0 0 2 2 2 0 MIF4G like zinc_ribbon_6 PF14599.6 KNE01293.1 - 2.9 8.0 7.7 2.6 8.1 2.3 2.7 2 0 0 2 2 2 0 Zinc-ribbon MFS_1 PF07690.16 KNE01298.1 - 2.7e-30 105.5 54.8 7.6e-29 100.7 24.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KNE01298.1 - 0.016 14.1 21.4 0.12 11.2 19.3 2.5 1 1 1 2 2 2 0 MFS_1 like family Hum_adeno_E3A PF05393.11 KNE01298.1 - 0.1 12.6 0.0 0.34 10.9 0.0 1.9 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein SspH PF08141.12 KNE01298.1 - 0.23 11.6 0.0 6.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Small acid-soluble spore protein H family DUF1616 PF07760.11 KNE01298.1 - 0.23 10.8 0.8 7.8 5.8 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) BolA PF01722.18 KNE01299.1 - 2.1e-18 66.3 0.0 4.3e-18 65.4 0.0 1.4 1 1 0 1 1 1 1 BolA-like protein RhoGAP PF00620.27 KNE01300.1 - 1.9e-35 121.9 0.3 3.7e-35 121.0 0.3 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KNE01300.1 - 1.3e-27 95.8 52.9 1.4e-10 41.2 11.3 4.6 4 0 0 4 4 4 4 LIM domain zf-C2H2_4 PF13894.6 KNE01300.1 - 0.21 12.5 0.1 0.21 12.5 0.1 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger PIG-H PF10181.9 KNE01304.1 - 1.1e-19 70.0 0.1 2e-19 69.2 0.1 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Myb_DNA-bind_7 PF15963.5 KNE01305.1 - 4.1e-25 87.5 0.2 4.1e-25 87.5 0.2 2.3 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KNE01305.1 - 3.6e-06 27.0 0.0 3.6e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KNE01305.1 - 0.052 13.8 2.2 0.056 13.7 0.3 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 KNE01305.1 - 0.091 13.0 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 WD40 PF00400.32 KNE01306.1 - 6.9e-13 48.9 1.9 0.012 16.5 0.1 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat WD40_like PF17005.5 KNE01306.1 - 0.025 13.9 0.2 0.094 12.0 0.2 1.8 1 1 0 1 1 1 0 WD40-like domain CDC45 PF02724.14 KNE01306.1 - 1 7.5 5.9 1.5 7.0 5.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Hist_deacetyl PF00850.19 KNE01307.1 - 9.6e-89 297.9 0.0 1.5e-88 297.3 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 KNE01307.1 - 3.5e-58 196.8 0.1 1e-57 195.2 0.1 1.8 2 1 0 2 2 2 1 Arb2 domain Pkinase PF00069.25 KNE01309.1 - 1.8e-43 148.8 0.0 2.7e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE01309.1 - 2.7e-26 92.4 0.0 3.9e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNE01309.1 - 0.0078 15.6 0.0 0.017 14.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KNE01309.1 - 0.066 12.1 2.9 0.086 11.8 0.0 2.4 2 1 1 3 3 3 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KNE01309.1 - 0.1 11.6 0.1 0.24 10.4 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 Methyltr_RsmB-F PF01189.17 KNE01310.1 - 5.4e-21 75.1 0.0 1e-20 74.2 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Iso_dh PF00180.20 KNE01311.1 - 8.3e-100 334.3 0.0 1.5e-99 333.5 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Transp_cyt_pur PF02133.15 KNE01313.1 - 9.6e-144 479.4 29.0 1.1e-143 479.2 29.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Calcyon PF06387.11 KNE01314.1 - 0.2 11.7 0.1 0.25 11.3 0.1 1.2 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) GrpE PF01025.19 KNE01315.1 - 1.9e-50 170.8 11.7 4.1e-50 169.7 11.7 1.5 1 1 0 1 1 1 1 GrpE DUF5523 PF17661.1 KNE01315.1 - 0.042 13.5 12.1 0.047 13.4 11.4 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5523) RuBisCO_large PF00016.20 KNE01315.1 - 0.23 10.6 1.0 0.27 10.4 1.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain SspB PF04386.13 KNE01315.1 - 0.23 11.4 7.2 0.44 10.4 7.2 1.7 1 1 0 1 1 1 0 Stringent starvation protein B O-antigen_lig PF13425.6 KNE01315.1 - 1.5 7.5 4.4 2.2 7.0 4.4 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4407 PF14362.6 KNE01315.1 - 3.4 6.9 8.3 3.9 6.7 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prominin PF05478.11 KNE01315.1 - 5.2 4.9 6.2 6.3 4.6 6.2 1.1 1 0 0 1 1 1 0 Prominin ALMT PF11744.8 KNE01315.1 - 6.3 5.5 6.1 8.5 5.1 6.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter ARD PF03079.14 KNE01315.1 - 7.4 6.7 8.1 2.8 8.1 4.3 1.8 1 1 1 2 2 2 0 ARD/ARD' family Fib_alpha PF08702.10 KNE01315.1 - 8 6.6 7.8 20 5.3 3.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Abhydrolase_1 PF00561.20 KNE01316.1 - 9e-12 45.2 0.0 1.7e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KNE01316.1 - 9.5e-07 28.3 0.0 7.7e-05 22.1 0.0 2.5 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KNE01316.1 - 3.9e-05 24.3 0.0 0.00014 22.6 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KNE01316.1 - 0.0033 17.1 0.0 0.014 15.0 0.0 2.0 2 0 0 2 2 2 1 Putative esterase Abhydrolase_2 PF02230.16 KNE01316.1 - 0.008 16.0 0.0 0.057 13.2 0.1 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 KNE01316.1 - 0.012 15.2 0.0 0.78 9.4 0.0 2.4 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Usg PF06233.12 KNE01316.1 - 0.077 13.2 0.4 0.22 11.7 0.4 1.8 1 0 0 1 1 1 0 Usg-like family Phage_base_V PF04717.12 KNE01316.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion system, phage-baseplate injector Sulfate_transp PF00916.20 KNE01317.1 - 1.1e-71 241.6 20.3 1.1e-71 241.6 20.3 1.5 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KNE01317.1 - 7.7e-17 61.0 0.1 1.6e-16 60.0 0.1 1.5 1 0 0 1 1 1 1 STAS domain Oxidored-like PF09791.9 KNE01319.1 - 2.8e-25 87.7 2.3 4.5e-25 87.1 2.3 1.3 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DPM3 PF08285.11 KNE01320.1 - 1.3e-30 105.4 0.0 1.5e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Tau95 PF09734.9 KNE01321.1 - 8.1e-36 123.9 0.5 8.1e-36 123.9 0.5 3.1 3 1 0 3 3 3 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KNE01321.1 - 2.5e-29 102.1 0.4 4.7e-29 101.2 0.4 1.5 1 0 0 1 1 1 1 Tau95 Triple barrel domain Ldh_1_C PF02866.18 KNE01322.1 - 2.2e-45 154.6 0.1 5.2e-45 153.4 0.1 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KNE01322.1 - 2.7e-44 150.7 0.5 4.2e-44 150.1 0.1 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KNE01322.1 - 0.0012 17.9 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 KNE01322.1 - 0.078 12.5 0.7 5.2 6.6 0.2 3.0 2 1 1 3 3 3 0 Family 4 glycosyl hydrolase DUF4574 PF15141.6 KNE01322.1 - 0.11 12.5 0.0 0.67 9.9 0.1 2.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 zf-C2H2 PF00096.26 KNE01323.1 - 3e-07 30.5 12.3 5.5e-05 23.4 1.4 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KNE01323.1 - 1.5e-06 28.6 9.7 0.011 16.5 0.3 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KNE01323.1 - 0.00011 22.5 18.5 0.00025 21.3 2.8 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 KNE01323.1 - 0.00021 21.5 1.2 0.091 13.2 0.5 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type ARS2 PF04959.13 KNE01323.1 - 0.0003 21.2 2.3 0.00097 19.6 2.3 1.9 1 0 0 1 1 1 1 Arsenite-resistance protein 2 zf-C2H2_6 PF13912.6 KNE01323.1 - 0.059 13.4 9.4 0.84 9.7 0.7 3.3 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KNE01323.1 - 0.32 11.3 4.0 8 6.8 0.5 3.1 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KNE01323.1 - 1.1 9.7 6.5 3.3 8.1 0.7 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KNE01323.1 - 1.7 9.0 7.1 7.9 6.9 1.5 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Aminotran_1_2 PF00155.21 KNE01324.1 - 1e-64 219.0 0.0 1.2e-64 218.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ADH_zinc_N PF00107.26 KNE01324.1 - 0.096 12.7 0.0 0.32 11.0 0.0 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase NIF PF03031.18 KNE01326.1 - 3e-45 153.8 0.0 2.5e-44 150.8 0.0 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase zinc_ribbon_6 PF14599.6 KNE01328.1 - 3.5e-23 81.4 2.2 3.5e-23 81.4 2.2 3.5 2 1 0 2 2 2 1 Zinc-ribbon zf-CHY PF05495.12 KNE01328.1 - 1.3e-16 60.8 22.3 1.3e-16 60.8 22.3 3.7 3 1 0 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 KNE01328.1 - 1.8e-07 31.4 8.9 1.8e-07 31.4 8.9 5.7 2 1 2 5 5 5 1 Ring finger domain zf-RING_UBOX PF13445.6 KNE01328.1 - 5.5e-05 23.1 3.1 5.5e-05 23.1 3.1 4.7 4 2 1 5 5 5 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KNE01328.1 - 5.7e-05 22.9 7.2 5.7e-05 22.9 7.2 5.4 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KNE01328.1 - 6.4e-05 22.7 9.9 6.4e-05 22.7 9.9 6.0 3 2 3 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KNE01328.1 - 0.00011 22.0 11.2 0.00011 22.0 11.2 5.9 4 2 2 6 6 6 1 zinc-RING finger domain PRP21_like_P PF12230.8 KNE01329.1 - 4.9e-57 193.3 13.7 4.9e-57 193.3 13.7 2.3 4 0 0 4 4 4 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KNE01329.1 - 3.1e-24 84.7 1.1 2.7e-14 52.9 0.1 2.7 2 0 0 2 2 2 2 Surp module Ribosomal_S6e PF01092.19 KNE01330.1 - 2.7e-58 195.4 0.1 5.3e-58 194.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e VKG_Carbox PF05090.14 KNE01330.1 - 0.23 10.3 0.2 0.3 9.9 0.2 1.1 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase DUF4574 PF15141.6 KNE01330.1 - 0.32 10.9 5.0 0.61 10.0 5.0 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 SRF-TF PF00319.18 KNE01331.1 - 6e-21 73.7 0.0 9.9e-21 73.0 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CAML PF14963.6 KNE01331.1 - 0.04 14.1 0.3 0.04 14.1 0.3 2.0 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand Menin PF05053.13 KNE01331.1 - 0.5 8.7 6.6 0.88 7.9 6.6 1.3 1 0 0 1 1 1 0 Menin Tim54 PF11711.8 KNE01331.1 - 1.3 7.7 9.9 0.014 14.2 1.4 1.9 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Sec16_C PF12931.7 KNE01333.1 - 1.3e-58 199.1 0.0 2e-58 198.5 0.0 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KNE01333.1 - 9.5e-12 45.6 1.4 3.7e-11 43.7 0.0 2.9 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region RRM_1 PF00076.22 KNE01334.1 - 1.7e-89 293.7 4.7 2.2e-22 78.6 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KNE01334.1 - 1.6e-21 76.2 1.8 2.7e-21 75.5 0.2 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KNE01334.1 - 6.1e-11 42.0 0.0 0.024 14.2 0.0 4.2 1 1 3 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KNE01334.1 - 4.9e-09 36.2 5.3 0.036 14.1 0.6 4.4 4 0 0 4 4 4 3 RNA binding motif RRM_7 PF16367.5 KNE01334.1 - 1.7e-07 31.2 0.6 0.2 11.8 0.0 4.9 4 1 0 4 4 4 2 RNA recognition motif YflT PF11181.8 KNE01334.1 - 1.4e-05 25.5 3.1 0.028 14.9 0.4 3.4 3 0 0 3 3 3 2 Heat induced stress protein YflT RRM_occluded PF16842.5 KNE01334.1 - 0.0002 21.1 0.0 0.044 13.6 0.0 3.1 3 0 0 3 3 3 1 Occluded RNA-recognition motif OB_RNB PF08206.11 KNE01334.1 - 0.0008 19.0 1.1 4.6 7.0 0.0 3.5 3 0 0 3 3 3 2 Ribonuclease B OB domain Nup35_RRM_2 PF14605.6 KNE01334.1 - 0.0011 19.0 0.8 7.5 6.6 0.0 4.0 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 KNE01334.1 - 0.0016 18.4 0.2 0.52 10.4 0.1 3.6 3 0 0 3 3 3 1 Limkain b1 DUF4078 PF13300.6 KNE01334.1 - 0.011 16.0 1.6 0.011 16.0 1.6 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4078) Nefa_Nip30_N PF10187.9 KNE01334.1 - 0.049 14.0 0.4 0.049 14.0 0.4 2.6 3 0 0 3 3 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 GIY-YIG PF01541.24 KNE01334.1 - 0.11 12.8 1.0 2.2 8.6 0.3 2.4 2 0 0 2 2 2 0 GIY-YIG catalytic domain SET_assoc PF11767.8 KNE01334.1 - 0.18 11.4 0.4 9.1 6.0 0.0 3.5 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated Glyco_transf_20 PF00982.21 KNE01335.1 - 2.5e-153 511.2 0.4 3.1e-153 510.9 0.4 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KNE01335.1 - 3.6e-72 242.3 0.0 8.9e-72 241.0 0.0 1.6 2 0 0 2 2 2 1 Trehalose-phosphatase DUF3437 PF11919.8 KNE01335.1 - 0.014 15.3 0.0 0.083 12.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Abhydrolase_1 PF00561.20 KNE01337.1 - 1.6e-18 67.3 0.0 6.2e-18 65.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KNE01337.1 - 3.1e-07 29.9 0.0 1.2e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KNE01337.1 - 5.2e-05 23.9 0.0 7.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF726 PF05277.12 KNE01337.1 - 0.014 14.3 0.0 0.021 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) ORC3_N PF07034.11 KNE01337.1 - 0.017 14.2 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus DUF915 PF06028.11 KNE01337.1 - 0.08 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Cutinase PF01083.22 KNE01337.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Cutinase VirJ PF06057.11 KNE01337.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Arrestin_C PF02752.22 KNE01338.1 - 3.9e-18 66.2 2.1 7e-17 62.1 0.1 3.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KNE01338.1 - 3.6e-08 33.6 0.2 0.00099 19.2 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain UL42 PF17638.2 KNE01338.1 - 0.3 11.1 3.9 10 6.1 0.1 2.5 2 0 0 2 2 2 0 HCMV UL42 Sec62 PF03839.16 KNE01339.1 - 8.8e-73 244.4 0.9 8.8e-73 244.4 0.9 1.3 2 0 0 2 2 2 1 Translocation protein Sec62 WD40 PF00400.32 KNE01340.1 - 0.0021 18.8 1.3 3.7 8.6 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat ECH_2 PF16113.5 KNE01342.1 - 1.8e-98 330.1 0.0 2.6e-98 329.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KNE01342.1 - 7.3e-23 81.2 0.0 4.7e-22 78.5 0.0 2.0 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Csc2 PF18320.1 KNE01342.1 - 0.02 13.8 0.1 0.032 13.2 0.1 1.2 1 0 0 1 1 1 0 Csc2 Crispr Pec_lyase_N PF04431.13 KNE01342.1 - 0.046 14.0 0.2 0.15 12.3 0.1 1.9 2 0 0 2 2 2 0 Pectate lyase, N terminus Actin PF00022.19 KNE01343.1 - 2.8e-65 220.5 0.0 6.5e-64 216.0 0.0 2.3 1 1 0 1 1 1 1 Actin DUF2247 PF10004.9 KNE01344.1 - 0.22 11.3 2.2 1.7 8.4 0.0 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2247) CHIP_TPR_N PF18391.1 KNE01344.1 - 0.56 11.0 7.4 2.3 9.0 7.4 2.0 1 0 0 1 1 1 0 CHIP N-terminal tetratricopeptide repeat domain EVC2_like PF12297.8 KNE01344.1 - 2.7 6.6 9.5 4.5 5.8 9.5 1.3 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Wtap PF17098.5 KNE01345.1 - 4.6e-05 23.4 12.9 0.00036 20.5 12.9 2.2 1 1 0 1 1 1 1 WTAP/Mum2p family KxDL PF10241.9 KNE01345.1 - 0.37 11.1 0.1 0.37 11.1 0.1 4.1 4 2 1 5 5 5 0 Uncharacterized conserved protein Peptidase_C97 PF05903.14 KNE01347.1 - 6.4e-39 133.2 0.0 7.2e-39 133.0 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KNE01347.1 - 0.06 13.7 0.1 0.085 13.2 0.1 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Rsbr_N PF08678.10 KNE01347.1 - 0.11 12.6 0.1 0.16 12.1 0.1 1.2 1 0 0 1 1 1 0 Rsbr N terminal SAYSvFN PF10260.9 KNE01347.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) EST1_DNA_bind PF10373.9 KNE01348.1 - 1.6e-28 100.0 2.6 1.6e-28 100.0 2.6 2.3 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KNE01348.1 - 3.1e-12 47.3 0.4 3.1e-12 47.3 0.4 3.0 3 0 0 3 3 3 1 Telomerase activating protein Est1 FA_desaturase PF00487.24 KNE01349.1 - 9.2e-26 91.2 8.3 1.6e-25 90.4 8.3 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 KNE01349.1 - 1.6e-16 59.5 0.3 2.9e-16 58.7 0.3 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) tRNA-synt_His PF13393.6 KNE01350.1 - 9.8e-37 126.9 0.0 6.3e-30 104.5 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KNE01350.1 - 1.4e-11 44.4 0.0 3e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 KNE01350.1 - 6.3e-05 22.6 0.0 0.0002 21.0 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 KNE01350.1 - 0.0021 17.2 0.0 0.012 14.7 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) ESCRT-II PF05871.12 KNE01350.1 - 0.1 12.8 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 ESCRT-II complex subunit Ribosomal_60s PF00428.19 KNE01350.1 - 0.13 12.9 0.4 0.13 12.9 0.4 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Pdase_C33_assoc PF14756.6 KNE01350.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase_C33-associated domain IDO PF01231.18 KNE01351.1 - 1.7e-148 495.0 0.0 2e-148 494.8 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase BAR PF03114.18 KNE01352.1 - 1.1e-59 202.0 8.4 1.5e-59 201.6 8.4 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KNE01352.1 - 1.2e-14 53.7 1.6 1.4e-14 53.4 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KNE01352.1 - 3.4e-13 49.2 0.1 5.8e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KNE01352.1 - 1.9e-08 33.8 0.0 4.4e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF755 PF05501.11 KNE01352.1 - 1.6 9.0 8.1 0.56 10.5 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Zn_clus PF00172.18 KNE01355.1 - 0.0097 16.0 9.8 0.014 15.5 9.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_1 PF00561.20 KNE01356.1 - 1.5e-14 54.3 0.0 1e-13 51.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNE01356.1 - 2.1e-13 51.4 0.0 2.7e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNE01356.1 - 4.4e-05 22.9 0.0 0.0094 15.2 0.0 2.4 2 1 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 KNE01356.1 - 0.0035 16.9 0.0 0.041 13.4 0.0 2.4 3 0 0 3 3 3 1 Dienelactone hydrolase family Chlorophyllase PF07224.11 KNE01356.1 - 0.0098 14.9 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Thioesterase PF00975.20 KNE01356.1 - 0.048 13.8 0.0 0.11 12.6 0.0 1.5 2 0 0 2 2 2 0 Thioesterase domain PMP1_2 PF08114.11 KNE01357.1 - 1.6e-11 43.8 0.3 1.7e-11 43.7 0.3 1.1 1 0 0 1 1 1 1 ATPase proteolipid family LapA_dom PF06305.11 KNE01357.1 - 0.022 14.6 1.6 0.024 14.4 1.6 1.0 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2749 PF10907.8 KNE01357.1 - 0.11 12.7 0.8 0.12 12.6 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) FeoB_associated PF12669.7 KNE01357.1 - 2.5 8.6 4.8 3.4 8.1 4.8 1.3 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Apo-CIII PF05778.12 KNE01359.1 - 0.27 10.9 2.2 1 9.0 0.1 2.5 3 0 0 3 3 3 0 Apolipoprotein CIII (Apo-CIII) RCR PF12273.8 KNE01361.1 - 9.6e-06 26.2 5.0 1.5e-05 25.6 5.0 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red BatD PF13584.6 KNE01361.1 - 0.0038 16.1 0.9 0.0049 15.8 0.9 1.1 1 0 0 1 1 1 1 Oxygen tolerance MFS_1 PF07690.16 KNE01361.1 - 0.047 12.6 0.0 0.053 12.4 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF2207 PF09972.9 KNE01361.1 - 0.11 11.2 0.2 0.12 11.1 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4381 PF14316.6 KNE01361.1 - 0.2 11.9 1.5 0.35 11.1 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) MFS_1 PF07690.16 KNE01362.1 - 3.2e-34 118.4 14.6 1.5e-25 89.9 0.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KNE01362.1 - 4.9e-07 29.0 4.0 4.9e-07 29.0 4.0 3.0 4 0 0 4 4 4 1 Sugar (and other) transporter UNC-93 PF05978.16 KNE01362.1 - 0.0015 18.2 0.7 0.0015 18.2 0.7 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 TRI12 PF06609.13 KNE01362.1 - 0.0052 15.3 1.5 0.0057 15.1 0.4 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ArAE_2_N PF10337.9 KNE01362.1 - 0.024 13.7 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal MFS_1 PF07690.16 KNE01363.1 - 6.6e-22 77.9 28.0 8.6e-17 61.1 5.1 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KNE01363.1 - 2.4e-07 30.0 2.4 2.4e-07 30.0 2.4 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KNE01363.1 - 0.0017 16.8 0.3 0.25 9.6 0.4 2.7 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family 7TM_GPCR_Sri PF10327.9 KNE01363.1 - 0.1 11.8 0.0 0.1 11.8 0.0 2.6 2 1 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Sri Ribonucleas_3_2 PF11469.8 KNE01365.1 - 0.11 12.9 0.0 0.13 12.7 0.0 1.1 1 0 0 1 1 1 0 Ribonuclease III Fungal_trans PF04082.18 KNE01367.1 - 5.4e-18 65.0 0.1 8.9e-18 64.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNE01367.1 - 5.3e-08 32.8 11.5 8.8e-08 32.2 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L10 PF00466.20 KNE01368.1 - 2.6e-26 91.6 0.8 8.7e-26 90.0 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 KNE01368.1 - 2.8e-22 78.5 0.0 4.4e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 KNE01368.1 - 2.6e-21 76.0 9.0 4e-21 75.4 6.7 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein Ribosomal_S16 PF00886.19 KNE01370.1 - 4.4e-24 84.3 0.1 6.7e-24 83.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 NUC173 PF08161.12 KNE01371.1 - 1.3e-73 247.0 1.0 1.1e-68 231.0 0.1 3.2 2 0 0 2 2 2 2 NUC173 domain Ipi1_N PF12333.8 KNE01371.1 - 0.0093 16.5 0.8 17 6.1 0.0 4.0 3 0 0 3 3 3 2 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.22 KNE01371.1 - 0.091 13.1 0.1 45 4.7 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat DUF29 PF01724.16 KNE01371.1 - 0.35 11.1 4.6 0.8 9.9 2.4 2.8 2 0 0 2 2 2 0 Domain of unknown function DUF29 L51_S25_CI-B8 PF05047.16 KNE01372.1 - 1.4e-09 37.7 0.0 1.8e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LigB PF02900.18 KNE01373.1 - 3.8e-27 95.1 0.0 5.2e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase IMD PF08397.11 KNE01375.1 - 0.15 11.4 7.7 0.31 10.4 7.7 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain BTB PF00651.31 KNE01376.1 - 3.5e-12 46.5 0.3 3.3e-05 24.1 0.0 3.6 2 1 0 2 2 2 2 BTB/POZ domain Ank_5 PF13857.6 KNE01376.1 - 8.8e-06 25.9 0.0 2.3e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KNE01376.1 - 0.0053 17.3 0.0 0.014 16.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KNE01376.1 - 0.0089 16.6 0.3 0.025 15.1 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KNE01376.1 - 0.032 14.7 0.1 0.11 13.0 0.1 2.0 1 0 0 1 1 1 0 Ankyrin repeat SPRY PF00622.28 KNE01376.1 - 0.049 13.7 0.0 0.085 13.0 0.0 1.3 1 0 0 1 1 1 0 SPRY domain DcpS_C PF11969.8 KNE01377.1 - 1.4e-31 109.3 0.7 2.8e-31 108.4 0.2 1.8 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 KNE01377.1 - 4.5e-31 107.8 0.2 7.7e-31 107.0 0.2 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DEAD PF00270.29 KNE01378.1 - 6e-41 140.1 0.1 9.9e-41 139.4 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 KNE01378.1 - 1.5e-18 66.8 0.1 4e-18 65.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 KNE01378.1 - 1.6e-17 63.8 0.0 4.1e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNE01378.1 - 1.4e-07 31.7 0.1 1.4e-07 31.7 0.1 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Sin_N PF04801.13 KNE01379.1 - 6.7e-18 65.1 0.0 1.1e-17 64.4 0.0 1.3 1 1 0 1 1 1 1 Sin-like protein conserved region MF_alpha PF04648.12 KNE01380.1 - 7.8e-08 32.3 40.0 0.16 12.3 1.6 5.2 5 0 0 5 5 5 5 Yeast mating factor alpha hormone MF_alpha_N PF05436.11 KNE01380.1 - 3.8e-07 29.9 0.1 8.4e-07 28.8 0.1 1.6 1 1 0 1 1 1 1 Mating factor alpha precursor N-terminus Apidaecin PF00807.17 KNE01380.1 - 0.13 12.4 14.7 22 5.2 0.2 5.6 6 0 0 6 6 6 0 Apidaecin UCH_1 PF13423.6 KNE01384.1 - 3.5e-55 187.9 0.1 5.5e-55 187.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KNE01384.1 - 2e-21 77.2 0.0 3.8e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 KNE01384.1 - 5.2e-06 26.1 0.0 1.3e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TCO89 PF10452.9 KNE01385.1 - 2.1e-14 53.5 35.1 2.1e-07 30.3 23.6 2.5 2 0 0 2 2 2 2 TORC1 subunit TCO89 Ribosomal_L28 PF00830.19 KNE01388.1 - 3.1e-07 30.5 1.3 3.1e-07 30.5 1.3 1.8 2 0 0 2 2 2 1 Ribosomal L28 family Pkinase PF00069.25 KNE01392.1 - 7e-70 235.4 0.0 9.2e-70 235.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE01392.1 - 2.2e-30 105.8 0.0 3.3e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KNE01392.1 - 4.8e-14 52.8 1.3 1.4e-13 51.3 1.3 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KNE01392.1 - 7.2e-09 35.4 0.0 2.1e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like C2 PF00168.30 KNE01392.1 - 8.2e-08 32.5 0.1 0.00029 21.1 0.0 2.7 2 0 0 2 2 2 2 C2 domain Haspin_kinase PF12330.8 KNE01392.1 - 0.0016 17.4 0.2 0.0044 16.0 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 KNE01392.1 - 0.011 15.4 0.1 0.52 9.9 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KNE01392.1 - 0.086 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KNE01392.1 - 0.11 12.4 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Adeno_E3_15_3 PF03307.14 KNE01392.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region vATP-synt_E PF01991.18 KNE01394.1 - 0.0066 15.9 4.1 0.012 15.1 4.1 1.3 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit CCDC-167 PF15188.6 KNE01394.1 - 0.22 11.9 4.6 0.66 10.4 4.6 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 GATase_4 PF13230.6 KNE01395.1 - 8e-14 51.2 0.0 3.5e-13 49.1 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 KNE01395.1 - 7.5e-11 42.4 0.0 1.3e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain SAPS PF04499.15 KNE01396.1 - 6.3e-188 625.5 1.3 6.3e-188 625.5 1.3 3.4 3 1 0 3 3 3 2 SIT4 phosphatase-associated protein Ribosomal_L21p PF00829.21 KNE01398.1 - 2.5e-07 30.9 0.1 2.8e-07 30.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein FMP23 PF17315.2 KNE01398.1 - 0.035 14.3 0.0 0.042 14.0 0.0 1.1 1 0 0 1 1 1 0 Found in mitochondrial proteome Pkinase PF00069.25 KNE01399.1 - 7e-71 238.7 0.0 1.4e-70 237.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE01399.1 - 3.5e-48 164.1 0.0 6.2e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNE01399.1 - 1.2e-11 44.4 0.0 4.5e-07 29.5 0.0 3.2 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 KNE01399.1 - 0.021 14.2 0.0 0.062 12.7 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sfi1 PF08457.10 KNE01400.1 - 5.5e-29 101.1 73.9 1.7e-22 79.7 51.1 3.1 2 1 1 3 3 3 3 Sfi1 spindle body protein Sigma54_CBD PF04963.13 KNE01400.1 - 0.067 13.0 0.1 13 5.6 0.0 2.9 2 0 0 2 2 2 0 Sigma-54 factor, core binding domain HTH_23 PF13384.6 KNE01400.1 - 0.13 12.1 0.1 0.71 9.7 0.1 2.4 1 0 0 1 1 1 0 Homeodomain-like domain DUSP PF06337.12 KNE01400.1 - 1.2 9.8 6.7 8.2 7.1 0.3 3.4 2 0 0 2 2 2 0 DUSP domain Glyco_transf_22 PF03901.17 KNE01401.1 - 9.7e-37 127.2 10.8 1.4e-36 126.7 10.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family EB1 PF03271.17 KNE01402.1 - 0.0023 18.1 0.0 0.003 17.8 0.0 1.3 1 0 0 1 1 1 1 EB1-like C-terminal motif cobW PF02492.19 KNE01403.1 - 8e-43 146.1 0.6 1.1e-42 145.6 0.6 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KNE01403.1 - 1.5e-06 28.1 0.0 3.2e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 KNE01403.1 - 0.00091 19.2 2.0 0.76 9.7 0.1 2.7 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KNE01403.1 - 0.0067 16.5 0.1 0.035 14.2 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KNE01403.1 - 0.008 15.9 0.5 0.028 14.2 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KNE01403.1 - 0.014 15.7 0.3 0.96 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KNE01403.1 - 0.014 15.9 0.1 0.014 15.9 0.1 2.5 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.19 KNE01403.1 - 0.017 14.6 0.1 0.03 13.8 0.1 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 KNE01403.1 - 0.02 15.4 0.3 0.12 12.9 0.1 2.2 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 KNE01403.1 - 0.025 15.0 0.0 0.066 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KNE01403.1 - 0.058 14.0 0.6 0.14 12.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain Tim54 PF11711.8 KNE01404.1 - 8e-129 429.7 2.8 1.1e-128 429.3 2.8 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 NYD-SP28 PF14772.6 KNE01404.1 - 0.022 14.8 6.5 0.081 13.0 6.5 1.9 1 0 0 1 1 1 0 Sperm tail DUF4351 PF14261.6 KNE01404.1 - 0.033 14.2 0.1 3.8 7.6 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) NIR_SIR PF01077.22 KNE01404.1 - 0.054 13.0 0.2 0.89 9.1 0.0 2.2 2 0 0 2 2 2 0 Nitrite and sulphite reductase 4Fe-4S domain YtxH PF12732.7 KNE01404.1 - 4.5 7.9 6.0 3.8 8.1 0.5 3.2 2 1 0 2 2 2 0 YtxH-like protein ELFV_dehydrog PF00208.21 KNE01405.1 - 1e-85 287.4 6.5 1.2e-85 287.1 6.5 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KNE01405.1 - 1.1e-49 167.6 0.0 2.2e-49 166.6 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Transposase_24 PF03004.14 KNE01406.1 - 0.009 16.1 0.2 0.012 15.7 0.2 1.1 1 0 0 1 1 1 1 Plant transposase (Ptta/En/Spm family) zf-Nse PF11789.8 KNE01407.1 - 9.2e-20 70.2 0.1 2e-19 69.2 0.0 1.6 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 KNE01407.1 - 2.5e-05 24.4 0.0 5.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-RING_UBOX PF13445.6 KNE01407.1 - 0.0088 16.1 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KNE01407.1 - 0.017 14.9 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TALPID3 PF15324.6 KNE01407.1 - 0.19 9.4 0.4 0.24 9.1 0.4 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Phosphodiest PF01663.22 KNE01408.1 - 2.6e-84 283.8 1.2 2.6e-84 283.8 1.2 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KNE01408.1 - 0.014 14.8 0.1 0.36 10.2 0.0 2.3 2 0 0 2 2 2 0 Sulfatase Sda PF08970.10 KNE01408.1 - 0.097 12.4 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 Sporulation inhibitor A NIF3 PF01784.18 KNE01409.1 - 1.2e-54 185.5 0.0 1.5e-54 185.2 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) LapA_dom PF06305.11 KNE01413.1 - 0.0046 16.7 0.0 0.0046 16.7 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain FlgT_N PF16548.5 KNE01413.1 - 0.031 14.8 1.0 0.1 13.1 1.0 1.9 1 0 0 1 1 1 0 Flagellar assembly protein T, N-terminal domain DUF885 PF05960.11 KNE01413.1 - 0.032 13.9 2.4 0.13 11.9 0.2 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) Pox_A_type_inc PF04508.12 KNE01413.1 - 0.11 12.4 1.3 0.36 10.7 1.3 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF2130 PF09903.9 KNE01413.1 - 7.5 5.7 8.0 0.22 10.7 1.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) HIG_1_N PF04588.13 KNE01414.1 - 9.9e-17 60.9 0.3 1.7e-16 60.1 0.3 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region PEARLI-4 PF05278.12 KNE01414.1 - 0.17 11.5 8.4 0.23 11.0 8.4 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Atg14 PF10186.9 KNE01414.1 - 1.3 8.0 6.2 1.8 7.6 6.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ChAPs PF09295.10 KNE01416.1 - 3e-146 487.5 0.6 3.9e-146 487.1 0.6 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 KNE01416.1 - 3.1e-09 37.2 0.6 0.00027 21.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KNE01416.1 - 2.2e-06 27.8 3.8 0.00071 19.8 0.2 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KNE01416.1 - 5.7e-05 23.0 1.4 3.5 8.1 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KNE01416.1 - 0.00026 20.9 1.3 0.8 10.0 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KNE01416.1 - 0.00052 20.6 2.9 0.046 14.5 0.3 3.6 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KNE01416.1 - 0.0013 19.3 0.1 0.01 16.5 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KNE01416.1 - 0.034 14.5 0.2 9.7 6.8 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TetR_C_10 PF16295.5 KNE01416.1 - 0.045 14.0 0.0 0.14 12.4 0.0 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TPR_1 PF00515.28 KNE01416.1 - 0.12 12.3 0.1 48 4.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TFIID-31kDa PF02291.15 KNE01417.1 - 1.7e-50 170.1 0.1 2.1e-50 169.9 0.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TPK_catalytic PF04263.16 KNE01418.1 - 4.1e-34 117.2 0.0 5.9e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KNE01418.1 - 2.8e-11 43.0 0.4 5e-11 42.1 0.4 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain DUF1713 PF08213.11 KNE01419.1 - 1.5e-10 40.8 21.4 2.3e-10 40.2 21.4 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Vel1p PF10339.9 KNE01419.1 - 0.028 13.8 0.0 0.033 13.6 0.0 1.1 1 0 0 1 1 1 0 Yeast-specific zinc responsive Ham1p_like PF01725.16 KNE01420.1 - 1.5e-55 188.0 0.0 1.7e-55 187.8 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DUF3602 PF12223.8 KNE01421.1 - 3.7e-28 97.9 21.0 4.7e-17 62.4 2.2 4.0 1 1 3 4 4 4 4 Protein of unknown function (DUF3602) DUF3484 PF11983.8 KNE01421.1 - 0.32 12.2 0.0 0.32 12.2 0.0 2.3 3 1 0 3 3 3 0 Membrane-attachment and polymerisation-promoting switch DUF1190 PF06693.11 KNE01421.1 - 0.55 10.6 9.4 2 8.8 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1190) Fcf1 PF04900.12 KNE01426.1 - 1.6e-35 121.4 0.3 2.6e-35 120.8 0.3 1.3 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KNE01426.1 - 6.8e-14 52.2 0.0 1.2e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 PIN like domain Imm-NTF2 PF15655.6 KNE01426.1 - 0.015 15.6 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 NTF2 fold immunity protein Metallophos PF00149.28 KNE01427.1 - 2.6e-07 31.4 3.3 8.3e-07 29.7 3.3 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PilP PF04351.13 KNE01429.1 - 0.16 11.9 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Pilus assembly protein, PilP SBF PF01758.16 KNE01430.1 - 1.1e-53 181.9 11.2 1.1e-53 181.9 11.2 1.8 2 0 0 2 2 2 1 Sodium Bile acid symporter family Trypan_PARP PF05887.11 KNE01431.1 - 0.015 15.3 0.3 0.018 15.0 0.3 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Glyco_tran_28_C PF04101.16 KNE01432.1 - 2.8e-23 82.7 0.0 3.4e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 KNE01432.1 - 0.091 12.0 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 Hydrolase_6 PF13344.6 KNE01432.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.4 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase TFIID-18kDa PF02269.16 KNE01433.1 - 5e-20 71.3 0.1 7.6e-20 70.7 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIID-31kDa PF02291.15 KNE01433.1 - 0.0026 17.8 0.0 0.0033 17.5 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DUF1931 PF09123.11 KNE01433.1 - 0.0026 17.9 0.0 0.0038 17.3 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1931) Bromo_TP PF07524.13 KNE01433.1 - 0.0065 16.4 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 KNE01433.1 - 0.0071 16.6 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KNE01433.1 - 0.015 15.7 5.7 0.028 14.8 0.0 2.8 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KNE01433.1 - 0.042 14.0 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold DUF1639 PF07797.14 KNE01433.1 - 0.97 9.5 7.5 8.1 6.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) PMT PF02366.18 KNE01436.1 - 1.5e-80 270.3 16.2 1.5e-80 270.3 16.2 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KNE01436.1 - 3.2e-62 209.7 24.8 3.2e-62 209.7 24.8 1.8 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KNE01436.1 - 4.4e-48 163.6 0.5 8.8e-48 162.6 0.5 1.5 1 0 0 1 1 1 1 MIR domain Ins145_P3_rec PF08709.11 KNE01436.1 - 0.0051 16.0 0.0 0.0097 15.1 0.0 1.3 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor HAGH_C PF16123.5 KNE01439.1 - 1.4e-18 67.2 0.0 2.4e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KNE01439.1 - 1.1e-13 51.7 2.9 8.9e-13 48.7 3.0 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KNE01439.1 - 0.015 14.8 2.0 0.11 12.0 2.0 2.2 1 1 0 1 1 1 0 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.20 KNE01439.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Y_phosphatase2 PF03162.13 KNE01440.1 - 1e-42 145.5 0.2 7.6e-41 139.4 0.2 2.0 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KNE01440.1 - 2.2e-06 27.8 0.0 2.6e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Vhr1 PF04001.13 KNE01441.1 - 6.8e-43 144.9 5.1 1.7e-42 143.6 5.1 1.6 1 0 0 1 1 1 1 Transcription factor Vhr1 DUF4246 PF14033.6 KNE01442.1 - 8.7e-126 420.7 0.2 1e-125 420.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 KNE01442.1 - 0.0043 17.4 0.0 0.0097 16.3 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 KNE01442.1 - 0.066 14.1 0.0 0.16 12.9 0.0 1.7 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily KHA PF11834.8 KNE01442.1 - 0.13 12.4 0.0 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 KHA, dimerisation domain of potassium ion channel Arginosuc_synth PF00764.19 KNE01444.1 - 7.4e-160 532.5 0.0 8.5e-160 532.3 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KNE01444.1 - 2.6e-05 23.8 0.0 4.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KNE01444.1 - 0.00071 18.5 0.1 0.0011 17.8 0.1 1.3 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 KNE01444.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase ArAE_2_N PF10337.9 KNE01445.1 - 6.2e-109 365.1 4.5 6.2e-109 365.1 4.5 2.1 2 0 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 KNE01445.1 - 2.8e-59 200.7 0.2 3.9e-58 197.0 0.3 2.5 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 KNE01445.1 - 2.4e-09 37.4 12.2 2.4e-09 37.4 12.2 3.7 3 1 1 4 4 4 1 Fusaric acid resistance protein-like COG6 PF06419.11 KNE01445.1 - 0.003 15.9 1.5 0.0063 14.8 1.5 1.5 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 HTH_26 PF13443.6 KNE01445.1 - 0.17 12.3 0.0 0.93 10.0 0.0 2.2 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HALZ PF02183.18 KNE01445.1 - 0.43 10.8 2.7 6.7 7.0 4.1 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Cupin_8 PF13621.6 KNE01446.1 - 5.9e-09 36.0 0.0 9.4e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain JHD PF17811.1 KNE01446.1 - 4.2e-08 33.7 0.0 9.2e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Jumonji helical domain PHD PF00628.29 KNE01446.1 - 7.1e-07 29.0 8.8 1.3e-06 28.2 8.8 1.4 1 0 0 1 1 1 1 PHD-finger JmjC PF02373.22 KNE01446.1 - 4e-05 24.0 0.0 0.0001 22.7 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 KNE01446.1 - 0.0078 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_1 PF00190.22 KNE01446.1 - 0.012 15.2 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 Cupin Cupin_2 PF07883.11 KNE01446.1 - 0.18 11.6 0.0 0.5 10.1 0.0 1.8 1 0 0 1 1 1 0 Cupin domain PHD_2 PF13831.6 KNE01446.1 - 0.33 10.5 4.9 0.63 9.6 4.9 1.5 1 0 0 1 1 1 0 PHD-finger BCDHK_Adom3 PF10436.9 KNE01447.1 - 1.3e-26 93.3 1.7 2.3e-26 92.6 1.7 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KNE01447.1 - 4.3e-10 40.1 0.0 1.1e-09 38.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KNE01447.1 - 1.7e-05 24.6 0.0 3.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KNE01447.1 - 0.00071 19.5 0.0 0.047 13.6 0.0 2.4 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain DUF2013 PF09431.10 KNE01449.1 - 1.1e-36 126.0 4.2 2.5e-36 124.9 4.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Lipin_mid PF16876.5 KNE01449.1 - 0.069 13.3 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain Colicin PF01024.19 KNE01449.1 - 0.11 12.4 0.1 0.18 11.7 0.1 1.2 1 0 0 1 1 1 0 Colicin pore forming domain Ank_2 PF12796.7 KNE01450.1 - 1.5e-25 89.6 0.6 2.3e-09 37.7 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KNE01450.1 - 6.3e-24 84.0 2.0 3.8e-07 30.5 0.8 4.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KNE01450.1 - 2.6e-18 64.2 0.7 0.026 15.0 0.0 6.9 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 KNE01450.1 - 1.1e-13 50.9 0.0 0.077 13.5 0.1 6.0 6 0 0 6 6 6 4 Ankyrin repeat SPX PF03105.19 KNE01450.1 - 4.2e-12 46.7 28.7 1e-05 25.7 3.0 4.0 4 1 1 5 5 5 3 SPX domain Ank_5 PF13857.6 KNE01450.1 - 3.9e-11 43.0 1.1 0.026 14.9 0.1 5.4 1 1 5 6 6 6 3 Ankyrin repeats (many copies) Ran_BP1 PF00638.18 KNE01451.1 - 7.8e-53 177.9 1.4 7.8e-53 177.9 1.4 1.6 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.23 KNE01451.1 - 1.5e-05 24.9 0.5 0.00022 21.1 0.5 2.2 1 1 0 1 1 1 1 WH1 domain SR-25 PF10500.9 KNE01451.1 - 0.0088 15.7 9.0 0.012 15.2 9.0 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Lig_C PF18330.1 KNE01451.1 - 0.029 14.4 0.0 0.029 14.4 0.0 2.3 2 1 0 2 2 2 0 Ligase Pab1020 C-terminal region CDC27 PF09507.10 KNE01451.1 - 0.098 12.0 17.6 0.13 11.6 17.6 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Afi1 PF07792.12 KNE01451.1 - 0.31 11.5 6.6 0.58 10.6 6.6 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CLPTM1 PF05602.12 KNE01451.1 - 0.42 9.6 2.6 0.54 9.2 2.6 1.2 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Zip PF02535.22 KNE01451.1 - 0.97 8.6 2.8 0.97 8.6 2.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DNA_pol_phi PF04931.13 KNE01451.1 - 2.8 5.9 15.5 3.8 5.5 15.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi TMEM214 PF10151.9 KNE01451.1 - 3.4 6.0 9.1 4.3 5.7 9.1 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator MAP17 PF15807.5 KNE01451.1 - 3.6 7.9 7.8 8.2 6.7 7.8 1.6 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 FAM176 PF14851.6 KNE01451.1 - 5.7 6.6 7.7 11 5.7 7.7 1.5 1 0 0 1 1 1 0 FAM176 family Sec62 PF03839.16 KNE01451.1 - 7.4 6.0 9.2 11 5.4 9.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 G0-G1_switch_2 PF15103.6 KNE01451.1 - 7.6 7.0 8.3 74 3.8 8.3 2.3 1 1 0 1 1 1 0 G0/G1 switch protein 2 DUF4820 PF16091.5 KNE01451.1 - 8.1 5.7 7.7 12 5.1 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CRM1_C PF08767.11 KNE01452.1 - 2.8e-124 414.5 1.6 2.8e-124 414.5 1.6 2.9 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 KNE01452.1 - 1.5e-36 125.7 9.9 2.5e-36 125.0 6.0 3.4 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KNE01452.1 - 5.7e-32 109.2 2.5 5.7e-32 109.2 2.5 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KNE01452.1 - 1e-28 99.1 2.4 4.9e-28 97.0 1.0 3.1 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 IBN_N PF03810.19 KNE01452.1 - 2.3e-15 56.3 1.8 5.7e-15 55.0 0.2 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain CRM1_repeat PF18777.1 KNE01452.1 - 4.7e-14 51.6 0.5 4.7e-14 51.6 0.5 2.2 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat V-ATPase_H_C PF11698.8 KNE01452.1 - 0.16 12.1 8.7 7.3 6.7 0.1 4.2 4 0 0 4 4 4 0 V-ATPase subunit H Ldh_1_N PF00056.23 KNE01453.1 - 3.7e-42 143.7 0.1 5.9e-42 143.1 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KNE01453.1 - 7e-42 143.2 0.1 1.1e-41 142.6 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 KNE01453.1 - 0.0033 16.5 0.0 0.0051 15.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_transf_56 PF07429.11 KNE01456.1 - 0.049 12.8 0.0 0.049 12.8 0.0 1.0 1 0 0 1 1 1 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 Trehalase PF01204.18 KNE01457.1 - 5.8e-177 589.6 1.4 7e-177 589.3 1.4 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KNE01457.1 - 5.2e-17 61.2 0.6 9.4e-17 60.4 0.6 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain polyprenyl_synt PF00348.17 KNE01458.1 - 3e-66 223.1 0.0 1.7e-60 204.2 0.0 2.5 2 1 0 2 2 2 2 Polyprenyl synthetase PhoU PF01895.19 KNE01458.1 - 0.067 13.7 0.0 0.25 11.8 0.0 2.0 1 0 0 1 1 1 0 PhoU domain Ribosomal_L3 PF00297.22 KNE01459.1 - 6.1e-18 65.0 1.3 6e-17 61.7 0.3 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 Ribosomal_L6 PF00347.23 KNE01460.1 - 1.1e-18 67.7 0.9 1.5e-08 35.2 0.2 2.5 3 0 0 3 3 3 2 Ribosomal protein L6 Ribosomal_S4 PF00163.19 KNE01461.1 - 2.8e-12 47.4 0.5 4.5e-12 46.7 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 KNE01461.1 - 1.1e-08 34.7 0.0 2.6e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 S4 domain JAKMIP_CC3 PF16034.5 KNE01461.1 - 0.087 12.8 0.2 0.16 11.9 0.1 1.6 1 1 0 1 1 1 0 JAKMIP CC3 domain BioT2 PF15368.6 KNE01464.1 - 0.011 15.8 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis family BioT2 NAD_binding_6 PF08030.12 KNE01465.1 - 2e-22 80.0 0.0 4.2e-22 79.0 0.0 1.6 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KNE01465.1 - 1.6e-21 76.7 7.8 1.6e-21 76.7 7.8 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KNE01465.1 - 2.2e-20 72.8 0.0 4.4e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Acetyltransf_1 PF00583.25 KNE01468.1 - 7.4e-07 29.4 0.1 1.7e-05 25.0 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KNE01468.1 - 2.3e-05 24.8 0.0 4.4e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KNE01468.1 - 0.0094 15.9 0.0 1 9.4 0.0 2.7 2 1 0 2 2 2 1 FR47-like protein SNF2_N PF00176.23 KNE01469.1 - 2.4e-58 197.5 0.0 4.1e-58 196.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Cdh1_DBD_1 PF18196.1 KNE01469.1 - 3.8e-34 117.6 1.4 3.8e-34 117.6 1.4 3.8 4 0 0 4 4 4 1 Chromodomain helicase DNA-binding domain 1 DUF4208 PF13907.6 KNE01469.1 - 2.2e-26 92.1 2.2 4.3e-26 91.2 0.5 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.24 KNE01469.1 - 1.8e-22 79.0 8.8 1.5e-13 50.4 2.0 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KNE01469.1 - 2.6e-19 69.6 0.0 6.9e-19 68.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNE01469.1 - 2.9e-09 37.1 0.0 2e-08 34.4 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KNE01469.1 - 0.0023 17.7 0.0 0.005 16.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SLIDE PF09111.10 KNE01469.1 - 0.0027 17.7 0.0 0.016 15.3 0.0 2.4 1 0 0 1 1 1 1 SLIDE Myb_DNA-binding PF00249.31 KNE01469.1 - 0.024 14.8 0.0 0.088 13.0 0.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain CHDCT2 PF08074.11 KNE01469.1 - 0.052 13.7 2.3 0.15 12.2 0.0 3.0 4 0 0 4 4 4 0 CHDCT2 (NUC038) domain Uma2 PF05685.12 KNE01470.1 - 0.05 13.1 0.0 0.056 13.0 0.0 1.1 1 0 0 1 1 1 0 Putative restriction endonuclease ABC_tran PF00005.27 KNE01471.1 - 2.7e-33 115.4 0.0 8.1e-17 62.0 0.0 2.7 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 KNE01471.1 - 7e-13 48.2 5.6 1.9e-12 46.8 5.6 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 KNE01471.1 - 2.7e-11 43.8 0.5 0.096 12.5 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KNE01471.1 - 3.5e-11 43.0 3.2 0.00086 18.8 0.0 4.2 3 2 1 5 5 4 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.27 KNE01471.1 - 6e-08 32.2 3.3 6e-08 32.2 3.3 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA PF00004.29 KNE01471.1 - 1.8e-06 28.4 0.0 0.0053 17.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KNE01471.1 - 3.4e-05 24.1 0.0 0.0088 16.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_6 PF12837.7 KNE01471.1 - 4.4e-05 23.4 2.7 4.4e-05 23.4 2.7 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_15 PF13175.6 KNE01471.1 - 6.1e-05 22.9 0.6 0.21 11.3 0.0 2.9 2 1 0 3 3 3 2 AAA ATPase domain Fer4_10 PF13237.6 KNE01471.1 - 6.4e-05 23.0 8.6 0.001 19.1 0.1 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_16 PF13191.6 KNE01471.1 - 8.3e-05 23.0 0.0 0.11 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 KNE01471.1 - 0.00025 21.4 0.1 0.066 13.6 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Fer4_7 PF12838.7 KNE01471.1 - 0.00036 21.1 7.3 0.0014 19.2 0.4 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain RsgA_GTPase PF03193.16 KNE01471.1 - 0.0004 20.3 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KNE01471.1 - 0.00084 19.9 1.0 0.055 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.6 KNE01471.1 - 0.001 19.2 11.6 0.0027 17.8 11.6 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_24 PF13479.6 KNE01471.1 - 0.0013 18.5 0.7 0.17 11.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KNE01471.1 - 0.0017 18.3 0.1 0.022 14.8 0.0 2.2 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KNE01471.1 - 0.0017 18.3 1.0 0.24 11.3 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 KNE01471.1 - 0.0021 18.2 0.2 0.7 10.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KNE01471.1 - 0.0021 17.7 0.3 1.8 8.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Fer4_2 PF12797.7 KNE01471.1 - 0.0026 17.8 0.9 0.0026 17.8 0.9 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 KNE01471.1 - 0.0031 17.6 10.7 0.01 16.0 10.9 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Rad17 PF03215.15 KNE01471.1 - 0.0035 17.3 0.0 1.1 9.2 0.0 2.5 2 1 0 2 2 2 1 Rad17 P-loop domain SRP54 PF00448.22 KNE01471.1 - 0.0046 16.6 2.9 0.19 11.3 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_13 PF13166.6 KNE01471.1 - 0.0049 15.6 0.4 0.01 14.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain Fer4_16 PF13484.6 KNE01471.1 - 0.0065 17.4 0.2 0.0065 17.4 0.2 2.6 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain AAA_18 PF13238.6 KNE01471.1 - 0.0082 16.7 0.0 7.8 7.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain VirE PF05272.11 KNE01471.1 - 0.01 15.6 0.0 0.9 9.2 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E AAA_30 PF13604.6 KNE01471.1 - 0.012 15.4 0.8 0.5 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KNE01471.1 - 0.017 15.4 0.0 10 6.5 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DnaB_C PF03796.15 KNE01471.1 - 0.017 14.4 0.0 0.16 11.3 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_28 PF13521.6 KNE01471.1 - 0.018 15.3 0.0 11 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KNE01471.1 - 0.025 13.7 0.0 0.66 9.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Fer4_17 PF13534.6 KNE01471.1 - 0.035 14.6 0.2 0.035 14.6 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 KNE01471.1 - 0.041 14.3 4.6 0.14 12.6 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain Thymidylate_kin PF02223.17 KNE01471.1 - 0.052 13.2 0.9 6.3 6.4 0.1 3.3 3 0 0 3 3 3 0 Thymidylate kinase AAA_7 PF12775.7 KNE01471.1 - 0.09 12.3 0.4 0.73 9.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_14 PF13173.6 KNE01471.1 - 0.11 12.6 0.0 19 5.3 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 KNE01471.1 - 0.11 12.5 1.5 1 9.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) CLP1_P PF16575.5 KNE01471.1 - 0.12 12.1 0.2 0.75 9.6 0.0 2.1 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_25 PF13481.6 KNE01471.1 - 0.15 11.6 1.2 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KNE01471.1 - 0.33 10.8 1.1 4.4 7.2 0.0 2.7 2 0 0 2 2 2 0 NTPase Fer4_4 PF12800.7 KNE01471.1 - 1.1 9.9 14.9 0.26 11.9 2.8 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 KNE01471.1 - 2.4 9.3 15.7 0.17 12.9 3.5 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Myb_DNA-bind_6 PF13921.6 KNE01472.1 - 1.2e-08 35.0 0.9 7.3e-08 32.6 0.4 2.7 3 0 0 3 3 3 1 Myb-like DNA-binding domain HSA PF07529.13 KNE01472.1 - 3.2e-08 33.8 0.0 3.2e-08 33.8 0.0 3.0 3 0 0 3 3 3 1 HSA Myb_DNA-binding PF00249.31 KNE01472.1 - 0.021 15.0 0.1 0.054 13.7 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain AI-2E_transport PF01594.16 KNE01473.1 - 0.0022 17.2 3.2 0.0032 16.7 3.2 1.1 1 0 0 1 1 1 1 AI-2E family transporter NnrU PF07298.11 KNE01473.1 - 0.15 11.6 2.4 0.25 10.8 2.4 1.3 1 0 0 1 1 1 0 NnrU protein Sen15 PF09631.10 KNE01474.1 - 9.7e-25 86.8 0.0 1.1e-24 86.6 0.0 1.0 1 0 0 1 1 1 1 Sen15 protein SUN PF03856.13 KNE01476.1 - 1.5e-65 221.0 4.6 1.7e-65 220.9 4.6 1.0 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) AP3D1 PF06375.11 KNE01479.1 - 0.0097 16.2 26.8 0.013 15.7 26.8 1.2 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 UL41A PF17591.2 KNE01479.1 - 0.16 12.1 0.2 0.22 11.6 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus UL41A SWIRM-assoc_2 PF16496.5 KNE01479.1 - 0.99 8.2 19.8 1 8.1 19.8 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DUF3807 PF12720.7 KNE01479.1 - 1 9.6 22.3 1.1 9.4 22.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) RNA_pol_Rpc4 PF05132.14 KNE01479.1 - 3 8.2 16.1 3.6 8.0 16.1 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Vfa1 PF08432.10 KNE01479.1 - 4.4 7.6 24.2 5 7.4 24.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.12 KNE01479.1 - 7.6 6.3 17.2 8.3 6.1 17.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cellulose_synt PF03552.14 KNE01479.1 - 9.3 4.6 11.0 9.7 4.5 11.0 1.0 1 0 0 1 1 1 0 Cellulose synthase PPL5 PF18168.1 KNE01479.1 - 9.5 5.4 13.5 10 5.3 13.5 1.1 1 0 0 1 1 1 0 Prim-pol family 5 CENP-N PF05238.13 KNE01479.1 - 9.8 5.4 15.5 11 5.2 15.5 1.0 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Rhodanese PF00581.20 KNE01480.1 - 3.5e-18 66.1 0.0 3.9e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 Rhodanese-like domain RRP36 PF06102.12 KNE01481.1 - 1.2e-47 162.0 25.4 1.2e-47 162.0 25.4 2.1 1 1 1 2 2 2 1 rRNA biogenesis protein RRP36 VasI PF11319.8 KNE01481.1 - 0.036 13.7 0.3 0.088 12.5 0.1 1.7 1 1 0 1 1 1 0 Type VI secretion system VasI, EvfG, VC_A0118 Alg14 PF08660.11 KNE01482.1 - 1.9e-62 210.3 0.1 1.9e-62 210.3 0.1 1.3 2 0 0 2 2 2 1 Oligosaccharide biosynthesis protein Alg14 like ATP-grasp_2 PF08442.10 KNE01484.1 - 6.3e-43 146.7 0.6 9.6e-43 146.1 0.4 1.4 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KNE01484.1 - 6.4e-25 87.8 0.0 2e-24 86.2 0.0 1.9 1 0 0 1 1 1 1 CoA-ligase Proteasome PF00227.26 KNE01485.1 - 1.5e-53 181.2 0.1 1.9e-53 180.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KNE01485.1 - 2.3e-12 46.4 0.0 5.1e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GCP_N_terminal PF17681.1 KNE01486.1 - 1.1e-40 140.2 2.8 1.3e-40 140.0 0.4 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KNE01486.1 - 3.5e-19 69.4 5.4 7.5e-19 68.3 5.4 1.6 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal ATG7_N PF16420.5 KNE01487.1 - 1.2e-50 172.9 2.2 1e-49 169.9 2.2 2.0 1 1 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KNE01487.1 - 4.3e-45 154.0 0.0 6.5e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 KNE01487.1 - 0.00078 18.9 0.0 0.075 12.4 0.0 2.6 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KNE01487.1 - 0.0067 16.5 0.0 0.022 14.8 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KNE01487.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NMD3 PF04981.13 KNE01488.1 - 1.2e-78 263.9 0.2 2.4e-78 263.0 0.2 1.4 1 0 0 1 1 1 1 NMD3 family VPS11_C PF12451.8 KNE01488.1 - 0.11 12.7 3.9 0.23 11.7 3.9 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal FYVE PF01363.21 KNE01488.1 - 0.17 12.1 0.4 1.6 8.9 0.1 2.4 2 0 0 2 2 2 0 FYVE zinc finger CpXC PF14353.6 KNE01488.1 - 1.9 8.5 6.0 30 4.7 0.1 3.2 3 0 0 3 3 3 0 CpXC protein WRNPLPNID PF15017.6 KNE01488.1 - 3.1 8.7 0.0 3.1 8.7 0.0 3.2 2 1 0 2 2 2 0 Putative WW-binding domain and destruction box Bromodomain PF00439.25 KNE01489.1 - 1.3e-24 86.0 0.8 2.5e-24 85.1 0.8 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KNE01489.1 - 3e-08 33.9 0.0 6.7e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KNE01489.1 - 1.5e-05 25.0 0.1 3.8e-05 23.6 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KNE01489.1 - 0.001 19.5 0.1 0.0019 18.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Nop14 PF04147.12 KNE01489.1 - 1.9 6.6 47.7 2.6 6.1 47.7 1.1 1 0 0 1 1 1 0 Nop14-like family Glucosamine_iso PF01182.20 KNE01490.1 - 2.5e-64 217.2 0.0 2.9e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase CPDase PF07823.11 KNE01491.1 - 7.1e-40 136.8 0.2 9.8e-39 133.1 0.2 1.9 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein LigT_PEase PF02834.16 KNE01491.1 - 0.0026 17.9 0.3 2.5 8.4 0.0 2.6 3 0 0 3 3 3 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 KNE01491.1 - 0.01 15.7 1.6 0.13 12.1 0.2 2.3 1 1 0 2 2 2 0 2'-5' RNA ligase superfamily ParD_like PF11903.8 KNE01491.1 - 0.8 9.8 2.7 2.5 8.3 2.7 1.9 1 1 0 1 1 1 0 ParD-like antitoxin of type II bacterial toxin-antitoxin system HORMA PF02301.18 KNE01492.1 - 4.1e-19 69.0 0.1 1.1e-18 67.6 0.1 1.7 1 1 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 KNE01492.1 - 0.0071 16.2 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial HORMA domain 2 ATG101 PF07855.12 KNE01492.1 - 0.029 14.4 0.1 0.36 10.8 0.1 2.1 1 1 0 1 1 1 0 Autophagy-related protein 101 Cyclin_N PF00134.23 KNE01493.1 - 2.3e-10 40.3 0.3 7.4e-10 38.7 0.3 1.9 1 0 0 1 1 1 1 Cyclin, N-terminal domain YLP PF02757.17 KNE01493.1 - 0.091 12.7 0.5 0.29 11.2 0.5 1.9 1 0 0 1 1 1 0 YLP motif Porin_3 PF01459.22 KNE01494.1 - 8e-74 248.5 7.1 9e-74 248.3 7.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Hexapep_loop PF18776.1 KNE01494.1 - 0.067 12.8 0.2 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 Hexapeptide repeat including loop Macro_2 PF14519.6 KNE01495.1 - 9.1e-12 44.9 0.0 2.3e-11 43.5 0.0 1.7 1 1 0 1 1 1 1 Macro-like domain Macro PF01661.21 KNE01495.1 - 0.00013 22.0 0.0 0.00079 19.5 0.0 2.1 2 0 0 2 2 2 1 Macro domain NUDIX PF00293.28 KNE01496.1 - 2.9e-11 43.5 0.0 3.4e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Cpta_toxin PF07254.12 KNE01496.1 - 0.098 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Membrane-bound toxin component of toxin-antitoxin system BOP1NT PF08145.12 KNE01497.1 - 1.3e-104 349.7 5.8 2.5e-104 348.8 5.8 1.5 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KNE01497.1 - 3e-25 88.0 3.7 1.3e-08 35.3 0.2 6.1 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNE01497.1 - 8.8e-08 32.3 0.0 0.022 15.0 0.0 5.1 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KNE01497.1 - 0.12 10.9 0.0 0.25 10.0 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 RRM_1 PF00076.22 KNE01498.1 - 2.7e-15 55.9 0.1 6.3e-15 54.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KNE01498.1 - 0.05 13.7 0.1 0.32 11.1 0.0 2.3 1 1 1 2 2 2 0 RNA recognition motif Acyltransferase PF01553.21 KNE01499.1 - 0.00018 21.1 0.0 0.00042 19.9 0.0 1.6 1 1 0 1 1 1 1 Acyltransferase Histone_H2A_C PF16211.5 KNE01500.1 - 4.8e-20 71.0 1.2 8.4e-20 70.2 1.2 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KNE01500.1 - 4.9e-17 62.5 0.0 6.5e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KNE01500.1 - 7.9e-06 26.1 0.0 1.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KNE01504.1 - 5.7e-21 75.2 2.6 6.9e-21 75.0 2.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KNE01504.1 - 1.7e-07 31.4 0.2 3.7e-07 30.3 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KNE01504.1 - 0.0017 18.8 0.0 0.0028 18.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KNE01504.1 - 0.0066 16.5 0.4 0.0077 16.3 0.4 1.1 1 0 0 1 1 1 1 YscO-like protein CENP-W PF15510.6 KNE01504.1 - 0.079 13.2 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 CENP-W protein DUF3391 PF11871.8 KNE01504.1 - 0.13 12.8 2.1 0.17 12.4 1.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) PGAP1 PF07819.13 KNE01505.1 - 7.9e-90 300.6 0.0 1.2e-89 300.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KNE01505.1 - 3.2e-05 24.6 0.2 5.4e-05 23.9 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNE01505.1 - 0.0001 21.7 0.0 0.00016 21.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KNE01505.1 - 0.0014 18.4 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 KNE01505.1 - 0.035 13.9 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF676 PF05057.14 KNE01505.1 - 0.045 13.3 0.1 0.094 12.2 0.1 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) SUR7 PF06687.12 KNE01508.1 - 8.6e-18 64.7 4.2 9.8e-18 64.6 4.2 1.0 1 0 0 1 1 1 1 SUR7/PalI family QueT PF06177.11 KNE01508.1 - 0.75 10.2 8.8 0.98 9.8 8.8 1.2 1 0 0 1 1 1 0 QueT transporter DUF2207 PF09972.9 KNE01508.1 - 2.1 7.0 7.2 3.4 6.3 7.2 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) PRA1 PF03208.19 KNE01508.1 - 3.1 7.4 10.9 7.6 6.1 10.9 1.6 1 1 0 1 1 1 0 PRA1 family protein DUF3294 PF07957.11 KNE01511.1 - 1.1e-63 214.9 3.6 1.2e-63 214.8 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) SKA1 PF07160.12 KNE01511.1 - 0.035 14.0 0.5 0.035 14.0 0.5 1.6 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 RapA_C PF12137.8 KNE01511.1 - 0.04 13.0 2.8 0.045 12.8 0.8 1.8 2 0 0 2 2 2 0 RNA polymerase recycling family C-terminal DUF5039 PF16442.5 KNE01511.1 - 0.058 12.9 4.1 0.098 12.2 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5039) DUF1192 PF06698.11 KNE01511.1 - 0.073 13.1 3.1 3.2 7.9 0.2 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) FlxA PF14282.6 KNE01511.1 - 0.57 10.2 6.7 0.86 9.6 0.8 2.6 2 1 1 3 3 3 0 FlxA-like protein SlyX PF04102.12 KNE01511.1 - 0.94 10.1 7.7 1.2 9.8 0.9 2.8 2 1 1 3 3 3 0 SlyX Ribosomal_L2_C PF03947.18 KNE01512.1 - 6.2e-05 23.2 0.7 6.7e-05 23.1 0.7 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain RRM_1 PF00076.22 KNE01513.1 - 6.4e-11 41.9 4.2 3.5e-07 29.9 0.3 3.1 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF927 PF06048.11 KNE01513.1 - 0.12 11.9 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF927) Ribosomal_L29e PF01779.17 KNE01514.1 - 1.1e-20 73.7 17.4 1.4e-20 73.3 17.4 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family Ribosomal_L7Ae PF01248.26 KNE01515.1 - 8.4e-23 79.9 0.6 1.5e-22 79.2 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PQ-loop PF04193.14 KNE01516.1 - 4.1e-28 96.9 1.0 6.5e-18 64.3 0.4 3.4 4 0 0 4 4 4 2 PQ loop repeat TRAM_LAG1_CLN8 PF03798.16 KNE01516.1 - 0.051 13.3 5.1 1 9.0 0.9 2.2 2 0 0 2 2 2 0 TLC domain Aida_C2 PF14186.6 KNE01516.1 - 0.2 11.2 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal adhesion Fungal_trans PF04082.18 KNE01517.1 - 2.7e-05 23.3 2.5 5.1e-05 22.4 2.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Syntaxin-6_N PF09177.11 KNE01519.1 - 1.3 9.6 13.1 1.2 9.7 3.2 3.2 2 1 2 4 4 4 0 Syntaxin 6, N-terminal Nsp1_C PF05064.13 KNE01519.1 - 2.1 8.2 14.1 0.84 9.5 1.1 3.4 2 1 1 3 3 3 0 Nsp1-like C-terminal region Tnp_22_trimer PF17489.2 KNE01519.1 - 2.5 8.1 7.4 8.2 6.5 1.5 2.8 2 0 0 2 2 2 0 L1 transposable element trimerization domain Tropomyosin_1 PF12718.7 KNE01519.1 - 3.3 7.9 25.8 0.12 12.5 3.1 3.7 3 1 1 4 4 4 0 Tropomyosin like EF-hand_14 PF17959.1 KNE01519.1 - 3.5 8.0 9.4 1.6 9.2 4.6 2.8 2 2 0 2 2 2 0 EF-hand domain Atg14 PF10186.9 KNE01519.1 - 5.3 6.0 13.5 1.7 7.7 9.0 2.3 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 KNE01519.1 - 5.9 7.1 17.4 1.8 8.7 7.7 2.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF5082 PF16888.5 KNE01519.1 - 8.2 6.7 13.7 0.89 9.8 4.4 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) Tti2 PF10521.9 KNE01520.1 - 4.1e-48 164.3 0.1 5.1e-48 164.0 0.1 1.1 1 0 0 1 1 1 1 Tti2 family Indigoidine_A PF04227.12 KNE01521.1 - 9.8e-114 379.6 0.9 1.1e-113 379.4 0.9 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein Spp-24 PF07448.11 KNE01521.1 - 0.18 12.0 0.0 0.41 10.9 0.0 1.6 1 0 0 1 1 1 0 Secreted phosphoprotein 24 (Spp-24) cystatin-like domain PfkB PF00294.24 KNE01522.1 - 1.7e-14 53.8 0.0 1.9e-05 24.1 0.0 3.1 3 0 0 3 3 3 3 pfkB family carbohydrate kinase DnaB_2 PF07261.11 KNE01522.1 - 0.061 13.1 0.3 40 4.0 0.0 3.4 3 0 0 3 3 3 0 Replication initiation and membrane attachment DUF4830 PF16112.5 KNE01523.1 - 0.028 14.9 0.8 0.07 13.6 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4830) AXH PF08517.12 KNE01523.1 - 0.34 11.5 6.2 4.9 7.7 0.3 2.2 2 0 0 2 2 2 0 Ataxin-1 and HBP1 module (AXH) Chalcone_2 PF16035.5 KNE01524.1 - 2.1e-45 155.0 0.0 2.4e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 KNE01524.1 - 3.9e-05 23.8 0.0 0.35 11.0 0.0 2.1 1 1 1 2 2 2 2 Chalcone isomerase-like NTP_transferase PF00483.23 KNE01525.1 - 6.8e-55 186.3 0.0 9.1e-55 185.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KNE01525.1 - 4e-11 43.5 0.0 5.8e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 KNE01525.1 - 1.8e-09 37.0 4.3 5.1e-08 32.3 0.4 3.2 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KNE01525.1 - 0.00012 21.7 1.4 0.61 9.9 0.3 3.1 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase MFS_1 PF07690.16 KNE01527.1 - 1.4e-17 63.7 21.7 2.2e-17 63.0 21.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4044 PF13253.6 KNE01527.1 - 3.5 7.2 6.5 4.5 6.9 2.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) FBPase PF00316.20 KNE01528.1 - 1.5e-79 265.9 0.4 2e-79 265.5 0.4 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 KNE01528.1 - 0.011 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Inositol monophosphatase family NdhM PF10664.9 KNE01528.1 - 0.03 14.6 0.0 0.058 13.7 0.0 1.5 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M SecY PF00344.20 KNE01531.1 - 7.4e-66 222.5 12.3 9.4e-66 222.1 12.3 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KNE01531.1 - 5.6e-15 54.9 0.1 5.6e-15 54.9 0.1 2.5 2 0 0 2 2 2 1 Plug domain of Sec61p AAA PF00004.29 KNE01532.1 - 1.8e-37 128.7 0.0 4.4e-37 127.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KNE01532.1 - 2.4e-08 33.8 0.1 1.4e-06 28.2 0.0 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 KNE01532.1 - 6.1e-06 26.1 0.0 1.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KNE01532.1 - 1.7e-05 25.1 0.2 0.0071 16.6 0.1 3.0 1 1 1 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 KNE01532.1 - 3.2e-05 23.7 0.0 6.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KNE01532.1 - 0.00022 21.6 0.7 0.0067 16.8 0.0 3.1 2 1 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 KNE01532.1 - 0.00034 19.9 0.0 0.00074 18.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KNE01532.1 - 0.00097 19.1 0.0 0.0045 17.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KNE01532.1 - 0.0016 18.6 0.0 0.0042 17.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KNE01532.1 - 0.0049 16.9 0.0 0.024 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KNE01532.1 - 0.0077 16.0 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KNE01532.1 - 0.0086 16.2 0.0 0.025 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KNE01532.1 - 0.0095 15.3 0.1 0.0095 15.3 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 KNE01532.1 - 0.015 14.7 0.0 3.5 7.0 0.0 2.6 1 1 1 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 KNE01532.1 - 0.019 14.1 0.1 0.064 12.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 KNE01532.1 - 0.044 13.4 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KNE01532.1 - 0.044 14.2 1.3 0.7 10.3 0.0 2.9 3 0 0 3 3 2 0 RNA helicase AAA_7 PF12775.7 KNE01532.1 - 0.06 12.9 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KNE01532.1 - 0.078 12.7 0.2 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KNE01532.1 - 0.08 12.9 0.0 0.25 11.2 0.0 1.9 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 KNE01532.1 - 0.1 11.9 0.0 2.1 7.6 0.0 2.4 1 1 1 2 2 2 0 KaiC PhoH PF02562.16 KNE01532.1 - 0.14 11.6 0.0 0.44 10.0 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 KNE01532.1 - 0.26 11.9 3.9 0.31 11.6 0.0 2.9 4 0 0 4 4 2 0 AAA domain Apq12 PF12716.7 KNE01537.1 - 4.8e-06 26.4 12.0 4.8e-06 26.4 12.0 1.5 2 0 0 2 2 2 1 Nuclear pore assembly and biogenesis MFS_1 PF07690.16 KNE01538.1 - 2.5e-39 135.2 41.4 1.8e-36 125.8 44.2 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KNE01538.1 - 1.6e-17 63.2 26.2 4.1e-17 61.8 26.2 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KNE01538.1 - 3.8e-10 39.2 6.3 3.8e-10 39.2 6.3 3.5 2 1 1 3 3 3 1 Sugar (and other) transporter DUF443 PF04276.12 KNE01538.1 - 0.11 12.3 0.1 0.11 12.3 0.1 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF443) DnaJ-X PF14308.6 KNE01539.1 - 2.7e-57 193.6 17.2 2.7e-57 193.6 17.2 2.1 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 KNE01539.1 - 2.1e-23 82.2 0.2 2.1e-23 82.2 0.2 2.6 2 0 0 2 2 2 1 DnaJ domain DUF1045 PF06299.12 KNE01539.1 - 0.041 13.9 2.6 0.23 11.4 2.6 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1045) Homeodomain PF00046.29 KNE01539.1 - 0.089 12.7 2.1 0.37 10.7 2.1 2.2 1 0 0 1 1 1 0 Homeodomain Complex1_LYR PF05347.15 KNE01540.1 - 1.5e-16 60.2 1.2 1.8e-16 59.9 1.2 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KNE01540.1 - 2.1e-06 28.4 1.7 2.5e-06 28.2 1.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like FMO-like PF00743.19 KNE01541.1 - 5.7e-29 100.9 0.0 5.5e-10 38.3 0.1 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KNE01541.1 - 1.7e-12 47.3 1.6 6.5e-10 38.7 0.1 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KNE01541.1 - 1.4e-09 37.6 0.1 2.1e-08 33.7 0.1 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KNE01541.1 - 8.8e-09 35.5 0.1 2.9e-07 30.6 0.0 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KNE01541.1 - 2.3e-08 33.6 0.4 0.0057 15.8 0.0 3.8 1 1 2 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KNE01541.1 - 0.00021 21.4 0.1 0.0005 20.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KNE01541.1 - 0.0012 19.4 0.1 1.9 9.1 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KNE01541.1 - 0.0021 17.7 0.2 0.032 13.8 0.2 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KNE01541.1 - 0.043 13.1 0.4 2 7.6 0.1 2.7 3 0 0 3 3 3 0 Thi4 family Glu_dehyd_C PF16912.5 KNE01541.1 - 0.077 12.5 0.0 3.4 7.1 0.0 2.5 3 0 0 3 3 3 0 Glucose dehydrogenase C-terminus PglD_N PF17836.1 KNE01541.1 - 0.12 13.0 0.1 0.48 11.1 0.1 2.0 1 0 0 1 1 1 0 PglD N-terminal domain MFS_1 PF07690.16 KNE01542.1 - 3.4e-46 157.8 17.5 3.4e-46 157.8 17.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KNE01542.1 - 1.1e-08 34.4 1.1 1.1e-08 34.4 1.1 3.4 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 KNE01542.1 - 0.018 13.4 8.4 0.039 12.4 8.4 1.5 1 0 0 1 1 1 0 Transmembrane secretion effector RNase_Zc3h12a PF11977.8 KNE01543.1 - 0.0075 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Pho86 PF11124.8 KNE01544.1 - 3e-75 253.4 0.2 3.4e-75 253.2 0.2 1.0 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 Acetyltransf_1 PF00583.25 KNE01544.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Lectin_leg-like PF03388.13 KNE01545.1 - 1.1e-53 182.0 0.0 1.4e-53 181.6 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KNE01545.1 - 5.3e-08 33.1 0.0 8.3e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 KNE01545.1 - 0.0064 16.1 0.0 0.014 15.0 0.0 1.5 2 0 0 2 2 2 1 Legume lectin domain DUF1180 PF06679.12 KNE01545.1 - 0.016 15.6 0.9 0.052 14.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Det1 PF09737.9 KNE01545.1 - 0.022 13.8 0.5 0.074 12.1 0.3 1.8 2 0 0 2 2 2 0 De-etiolated protein 1 Det1 FeoB_C PF07664.12 KNE01545.1 - 0.066 12.9 1.0 0.14 11.9 0.1 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus DUF2304 PF10066.9 KNE01545.1 - 0.094 12.9 1.0 4.3 7.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) FtsL PF04999.13 KNE01545.1 - 0.18 11.8 0.2 0.18 11.8 0.2 2.3 3 0 0 3 3 3 0 Cell division protein FtsL ANAPC2 PF08672.11 KNE01546.1 - 0.035 14.6 0.1 0.076 13.5 0.1 1.7 1 1 0 1 1 1 0 Anaphase promoting complex (APC) subunit 2 AvrM_N PF18247.1 KNE01546.1 - 0.11 12.5 1.5 6.7 6.7 0.7 2.2 1 1 1 2 2 2 0 Flax-rust effector AvrM N-terminal domain DUF1456 PF07308.13 KNE01546.1 - 0.13 12.7 0.3 0.59 10.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1456) His_Phos_1 PF00300.22 KNE01547.1 - 1.4e-36 126.0 0.1 2e-36 125.5 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 KNE01547.1 - 0.00045 19.7 0.0 0.00057 19.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Sigma70_r4 PF04545.16 KNE01547.1 - 0.018 14.6 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 Put_Phosphatase PF06888.12 KNE01547.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative Phosphatase IU_nuc_hydro PF01156.19 KNE01550.1 - 1.6e-75 254.5 0.0 1.9e-75 254.3 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Abhydro_lipase PF04083.16 KNE01551.1 - 3.6e-18 64.9 0.0 7e-18 64.0 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KNE01551.1 - 0.00024 20.9 0.1 0.00043 20.0 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Uds1 PF15456.6 KNE01551.1 - 0.17 12.0 4.0 0.32 11.2 4.0 1.3 1 0 0 1 1 1 0 Up-regulated During Septation DASH_Spc19 PF08287.11 KNE01551.1 - 0.34 10.8 3.4 0.62 9.9 3.4 1.3 1 0 0 1 1 1 0 Spc19 CCDC53 PF10152.9 KNE01551.1 - 2.4 8.6 6.7 4.9 7.5 6.7 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex 2-Hacid_dh_C PF02826.19 KNE01555.1 - 1.4e-53 180.9 0.0 1.6e-52 177.4 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KNE01555.1 - 1.3e-09 37.9 0.0 2e-09 37.2 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KNE01555.1 - 0.0025 18.0 0.0 0.0059 16.8 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KNE01555.1 - 0.065 13.8 0.1 0.19 12.3 0.1 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 KNE01555.1 - 0.23 12.3 0.7 2.3 9.1 0.4 2.6 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Peptidase_M28 PF04389.17 KNE01556.1 - 6.5e-40 136.9 0.1 9.8e-40 136.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KNE01556.1 - 1.9e-13 50.2 0.1 7.2e-13 48.4 0.0 2.0 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 KNE01556.1 - 5.1e-05 23.1 0.0 0.00011 22.0 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KNE01556.1 - 0.0097 15.0 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase DnaJ PF00226.31 KNE01557.1 - 4.3e-21 74.8 3.6 1.6e-20 73.0 3.6 2.1 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 KNE01557.1 - 2.3e-05 24.0 0.0 0.0008 19.1 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KNE01557.1 - 0.0015 18.6 0.0 0.014 15.5 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KNE01557.1 - 0.004 17.1 0.0 0.11 12.7 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KNE01557.1 - 0.0078 16.3 0.0 0.026 14.7 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 KNE01557.1 - 0.056 14.1 0.9 1.4 9.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_125 PF06824.11 KNE01557.1 - 0.16 10.8 6.6 0.26 10.1 6.6 1.2 1 0 0 1 1 1 0 Metal-independent alpha-mannosidase (GH125) Presenilin PF01080.17 KNE01557.1 - 1.5 7.5 8.3 2.1 7.0 8.3 1.2 1 0 0 1 1 1 0 Presenilin GTA_holin_3TM PF11351.8 KNE01557.1 - 8.8 6.9 11.6 22 5.6 11.6 1.7 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release ALMT PF11744.8 KNE01557.1 - 9.2 5.0 9.0 96 1.6 8.6 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter AAA PF00004.29 KNE01558.1 - 3.8e-43 147.1 0.0 7e-43 146.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KNE01558.1 - 1.5e-13 50.3 0.0 3.3e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KNE01558.1 - 2.7e-07 30.6 0.0 8.2e-07 29.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KNE01558.1 - 8.3e-07 29.3 0.0 1.8e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 KNE01558.1 - 1.7e-06 27.9 0.5 4.9e-06 26.4 0.5 1.9 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 KNE01558.1 - 8.8e-06 26.0 0.5 0.0064 16.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KNE01558.1 - 1.1e-05 25.9 0.0 0.00018 21.9 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 KNE01558.1 - 0.00023 20.9 0.0 0.00046 20.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KNE01558.1 - 0.00081 19.6 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KNE01558.1 - 0.0015 19.1 0.1 0.033 14.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KNE01558.1 - 0.0032 17.2 0.0 0.0058 16.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_13 PF13166.6 KNE01558.1 - 0.011 14.4 0.2 0.21 10.2 0.3 2.0 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KNE01558.1 - 0.013 15.4 0.0 0.031 14.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KNE01558.1 - 0.014 14.7 0.0 0.034 13.4 0.0 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 KNE01558.1 - 0.016 15.4 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Tropomyosin PF00261.20 KNE01558.1 - 0.017 14.5 3.0 0.026 13.9 0.9 2.0 2 0 0 2 2 2 0 Tropomyosin AAA_11 PF13086.6 KNE01558.1 - 0.018 14.9 0.1 0.64 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KNE01558.1 - 0.021 14.9 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KNE01558.1 - 0.026 13.9 0.0 0.057 12.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KNE01558.1 - 0.029 14.0 0.0 0.068 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KNE01558.1 - 0.029 14.8 0.0 0.053 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 KNE01558.1 - 0.034 13.6 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 KNE01558.1 - 0.036 13.8 0.0 0.077 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 KNE01558.1 - 0.038 14.0 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE APG6_N PF17675.1 KNE01558.1 - 0.039 14.5 1.7 0.077 13.5 1.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region AAA_7 PF12775.7 KNE01558.1 - 0.045 13.3 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KNE01558.1 - 0.049 12.9 0.0 0.23 10.7 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.6 KNE01558.1 - 0.057 13.9 0.1 0.88 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Spc24 PF08286.11 KNE01558.1 - 0.071 13.4 0.5 0.24 11.7 0.2 2.0 2 0 0 2 2 1 0 Spc24 subunit of Ndc80 DivIC PF04977.15 KNE01558.1 - 0.078 12.8 2.5 0.19 11.6 2.5 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF2072 PF09845.9 KNE01558.1 - 0.084 13.1 0.5 0.17 12.1 0.5 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein CTC1_2 PF15491.6 KNE01558.1 - 0.088 12.1 0.2 0.14 11.4 0.2 1.2 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 ATPase PF06745.13 KNE01558.1 - 0.09 12.1 0.6 0.17 11.2 0.0 1.8 2 0 0 2 2 1 0 KaiC NB-ARC PF00931.22 KNE01558.1 - 0.091 11.9 0.0 0.25 10.5 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.26 KNE01558.1 - 0.094 12.4 0.0 0.55 9.9 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain NACHT PF05729.12 KNE01558.1 - 0.094 12.6 0.0 0.23 11.4 0.0 1.6 2 0 0 2 2 1 0 NACHT domain DUF4763 PF15960.5 KNE01558.1 - 0.13 11.6 2.3 0.24 10.7 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) ATG16 PF08614.11 KNE01558.1 - 0.2 11.8 4.4 0.31 11.2 4.4 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Laminin_II PF06009.12 KNE01558.1 - 0.63 10.0 3.5 12 5.9 2.4 2.7 2 1 0 3 3 2 0 Laminin Domain II EzrA PF06160.12 KNE01558.1 - 2.8 6.0 6.3 1.3 7.1 2.8 1.9 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF4713 PF15831.5 KNE01560.1 - 0.41 11.1 0.2 0.41 11.1 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4713) MIF4G PF02854.19 KNE01562.1 - 3.5e-43 147.7 0.4 3.5e-43 147.7 0.4 1.5 2 0 0 2 2 2 1 MIF4G domain eIF_4G1 PF12152.8 KNE01562.1 - 1.6e-16 60.2 0.1 5e-16 58.6 0.1 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 AAA PF00004.29 KNE01564.1 - 2.9e-17 63.3 0.7 3.2e-16 59.9 0.1 2.5 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KNE01564.1 - 5e-09 36.1 0.0 1.2e-08 34.8 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KNE01564.1 - 1.2e-07 31.9 0.1 3.2e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KNE01564.1 - 1.2e-07 31.8 0.0 3e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KNE01564.1 - 4.4e-06 27.3 0.0 2.9e-05 24.6 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_2 PF07724.14 KNE01564.1 - 5.2e-06 26.7 0.0 3.7e-05 23.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_assoc_2 PF16193.5 KNE01564.1 - 1e-05 25.8 0.1 5.8e-05 23.3 0.1 2.4 1 1 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 KNE01564.1 - 3.2e-05 24.4 0.4 0.0077 16.6 0.1 2.8 1 1 1 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 KNE01564.1 - 4.9e-05 23.1 0.0 0.0058 16.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.6 KNE01564.1 - 5.1e-05 23.1 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KNE01564.1 - 5.9e-05 23.4 4.0 0.00098 19.4 1.0 3.4 2 2 1 3 3 3 1 AAA domain AAA_28 PF13521.6 KNE01564.1 - 0.00089 19.5 0.0 0.0024 18.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KNE01564.1 - 0.0009 19.4 0.3 0.0025 18.0 0.1 2.0 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.6 KNE01564.1 - 0.0012 19.2 0.0 0.004 17.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KNE01564.1 - 0.0015 18.4 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KNE01564.1 - 0.0025 17.7 0.6 0.078 12.9 0.6 2.6 1 1 0 1 1 1 1 NACHT domain Mg_chelatase PF01078.21 KNE01564.1 - 0.0061 16.0 0.0 0.26 10.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KNE01564.1 - 0.0082 16.5 0.0 0.026 14.9 0.0 1.9 1 0 0 1 1 1 1 RNA helicase DNA_pol3_delta2 PF13177.6 KNE01564.1 - 0.0099 15.7 0.3 0.25 11.1 0.2 2.4 2 0 0 2 2 2 1 DNA polymerase III, delta subunit FliS PF02561.14 KNE01564.1 - 0.023 14.9 0.7 0.084 13.2 0.2 2.0 2 0 0 2 2 2 0 Flagellar protein FliS IstB_IS21 PF01695.17 KNE01564.1 - 0.031 14.0 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 KNE01564.1 - 0.052 13.4 0.1 0.4 10.6 0.0 2.3 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 KNE01564.1 - 0.083 12.1 0.0 0.16 11.2 0.0 1.5 1 1 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 KNE01564.1 - 0.086 12.7 1.8 0.33 10.8 0.4 2.6 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea ResIII PF04851.15 KNE01564.1 - 0.092 12.7 0.6 0.46 10.5 0.1 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 KNE01564.1 - 0.1 13.1 0.0 0.46 11.0 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 KNE01564.1 - 0.11 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KNE01564.1 - 0.14 11.7 0.1 0.35 10.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KNE01564.1 - 0.14 12.5 1.0 22 5.4 0.3 2.7 1 1 1 2 2 2 0 AAA domain Roc PF08477.13 KNE01564.1 - 0.15 12.3 0.0 0.85 9.8 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase LIM_bind PF01803.16 KNE01566.1 - 1.8e-42 145.5 0.0 1.8e-42 145.5 0.0 4.1 2 2 0 2 2 2 1 LIM-domain binding protein PAPA-1 PF04795.12 KNE01568.1 - 2.2e-16 60.4 6.0 2.2e-16 60.4 6.0 3.1 1 1 1 2 2 2 1 PAPA-1-like conserved region DUF883 PF05957.13 KNE01568.1 - 5.1 7.8 13.5 21 5.8 0.2 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Neugrin PF06413.11 KNE01571.1 - 6.9e-07 29.5 5.8 1.1e-06 28.9 5.2 1.6 1 1 0 1 1 1 1 Neugrin LMBR1 PF04791.16 KNE01571.1 - 0.44 9.4 6.9 0.52 9.2 6.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein VID27_N PF17748.1 KNE01572.1 - 1.7e-48 164.8 0.3 2.5e-48 164.2 0.2 1.3 1 1 0 1 1 1 1 VID27 N-terminal region Mrx7 PF10906.8 KNE01573.1 - 3.6e-24 84.8 0.2 4.1e-24 84.6 0.2 1.1 1 0 0 1 1 1 1 MIOREX complex component 7 DUF3945 PF13101.6 KNE01573.1 - 0.17 11.6 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) Ost4 PF10215.9 KNE01574.1 - 5.2e-12 45.4 0.7 7.8e-12 44.8 0.7 1.3 1 0 0 1 1 1 1 Oligosaccaryltransferase RGS PF00615.19 KNE01577.1 - 1.4e-05 25.4 0.0 2.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain bZIP_2 PF07716.15 KNE01578.1 - 1.4e-10 41.1 7.3 3.2e-10 39.9 7.3 1.7 1 0 0 1 1 1 1 Basic region leucine zipper FlxA PF14282.6 KNE01578.1 - 0.006 16.6 11.6 0.087 12.8 3.8 2.6 2 0 0 2 2 2 2 FlxA-like protein bZIP_1 PF00170.21 KNE01578.1 - 0.0073 16.4 7.1 0.019 15.1 7.1 1.7 1 0 0 1 1 1 1 bZIP transcription factor SWIRM-assoc_1 PF16495.5 KNE01579.1 - 0.052 13.5 0.4 0.07 13.1 0.4 1.2 1 0 0 1 1 1 0 SWIRM-associated region 1 CPSase_L_D2 PF02786.17 KNE01583.1 - 2e-80 269.3 0.1 3.6e-80 268.4 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KNE01583.1 - 6.2e-66 221.9 0.0 1.2e-65 221.0 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KNE01583.1 - 4.5e-39 133.4 0.1 1e-38 132.3 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KNE01583.1 - 7.5e-32 109.6 0.0 2.2e-31 108.1 0.0 1.9 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KNE01583.1 - 3e-27 95.8 0.1 5.7e-27 94.9 0.1 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KNE01583.1 - 2.3e-16 59.4 6.2 2.3e-16 59.4 6.2 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KNE01583.1 - 5.6e-08 32.5 3.7 0.00026 20.8 0.4 2.9 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KNE01583.1 - 1.3e-07 31.4 0.0 3.5e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KNE01583.1 - 9.6e-07 28.5 0.0 2.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KNE01583.1 - 2.4e-05 24.4 0.0 5.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.6 KNE01583.1 - 0.00046 20.1 0.6 0.0024 17.8 0.9 2.0 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain RimK PF08443.11 KNE01583.1 - 0.00082 19.0 0.0 0.007 16.0 0.0 2.2 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_D23 PF16576.5 KNE01583.1 - 0.0011 18.2 0.8 0.13 11.5 0.2 2.5 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 KNE01583.1 - 0.002 18.8 1.4 1.5 9.5 0.1 2.9 2 0 0 2 2 2 2 HlyD family secretion protein GCV_H PF01597.19 KNE01583.1 - 0.0032 17.4 0.9 0.014 15.3 0.9 2.1 1 0 0 1 1 1 1 Glycine cleavage H-protein ATPgrasp_ST PF14397.6 KNE01583.1 - 0.0081 15.4 0.0 0.038 13.2 0.0 2.1 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp NQRA PF05896.11 KNE01583.1 - 0.0082 15.6 0.6 0.016 14.7 0.6 1.3 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DASH_Duo1 PF08651.10 KNE01584.1 - 4.6e-20 71.2 5.1 7.8e-20 70.4 1.8 2.0 2 0 0 2 2 2 1 DASH complex subunit Duo1 DivIC PF04977.15 KNE01584.1 - 7.8e-05 22.4 9.1 0.0052 16.5 3.4 2.2 2 0 0 2 2 2 2 Septum formation initiator Uds1 PF15456.6 KNE01584.1 - 0.00088 19.4 3.4 0.0013 18.9 3.4 1.2 1 0 0 1 1 1 1 Up-regulated During Septation RasGAP_C PF03836.15 KNE01584.1 - 0.0011 19.2 2.2 0.01 16.0 0.5 2.1 2 0 0 2 2 2 1 RasGAP C-terminus DASH_Dad2 PF08654.10 KNE01584.1 - 0.0026 18.1 7.5 0.0036 17.7 1.6 2.1 1 1 1 2 2 2 1 DASH complex subunit Dad2 HALZ PF02183.18 KNE01584.1 - 0.0029 17.8 1.8 0.0029 17.8 1.8 2.1 2 1 0 2 2 2 1 Homeobox associated leucine zipper SlyX PF04102.12 KNE01584.1 - 0.0031 18.1 3.5 3.2 8.4 0.7 3.2 2 1 1 3 3 3 1 SlyX DUF4200 PF13863.6 KNE01584.1 - 0.0035 17.7 4.9 0.014 15.8 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) LPP PF04728.13 KNE01584.1 - 0.0052 17.1 4.8 0.57 10.6 0.4 2.3 2 0 0 2 2 2 2 Lipoprotein leucine-zipper DUF3450 PF11932.8 KNE01584.1 - 0.0064 15.8 7.7 0.11 11.8 2.8 2.0 1 1 0 2 2 2 2 Protein of unknown function (DUF3450) UPF0184 PF03670.13 KNE01584.1 - 0.0075 16.6 0.7 0.013 15.9 0.4 1.6 2 0 0 2 2 1 1 Uncharacterised protein family (UPF0184) JIP_LZII PF16471.5 KNE01584.1 - 0.0078 16.4 3.6 0.011 15.9 0.5 2.3 2 0 0 2 2 2 1 JNK-interacting protein leucine zipper II ABC_tran_CTD PF16326.5 KNE01584.1 - 0.016 15.4 3.6 0.063 13.5 0.6 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain NPV_P10 PF05531.12 KNE01584.1 - 0.018 15.5 5.0 1.4 9.4 0.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4709 PF15821.5 KNE01584.1 - 0.022 15.0 1.6 1.4 9.2 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) CLZ PF16526.5 KNE01584.1 - 0.03 14.7 2.7 0.087 13.2 0.3 2.2 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BRE1 PF08647.11 KNE01584.1 - 0.034 14.2 4.5 0.51 10.4 0.3 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DivIVA PF05103.13 KNE01584.1 - 0.036 14.1 4.1 0.26 11.4 0.3 2.1 2 0 0 2 2 2 0 DivIVA protein NYD-SP28_assoc PF14775.6 KNE01584.1 - 0.042 13.9 1.4 0.042 13.9 1.4 1.9 2 0 0 2 2 1 0 Sperm tail C-terminal domain TMF_DNA_bd PF12329.8 KNE01584.1 - 0.064 13.3 9.0 0.71 9.9 0.7 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.22 KNE01584.1 - 0.096 12.9 8.5 0.23 11.7 1.6 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain RPW8 PF05659.11 KNE01584.1 - 0.11 12.1 3.1 1 9.1 2.6 2.0 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 GAS PF13851.6 KNE01584.1 - 0.15 11.4 9.2 0.19 11.1 3.2 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 KNE01584.1 - 0.17 12.0 11.5 1.9 8.5 0.9 2.2 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein FlxA PF14282.6 KNE01584.1 - 0.18 11.8 9.4 1.5 8.9 2.6 2.2 2 0 0 2 2 2 0 FlxA-like protein APG6_N PF17675.1 KNE01584.1 - 0.2 12.2 8.2 0.51 10.9 8.2 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Alanine_zipper PF11839.8 KNE01584.1 - 0.28 11.6 2.8 1.1 9.6 0.3 2.3 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein DUF4140 PF13600.6 KNE01584.1 - 0.39 11.2 6.7 0.58 10.6 2.1 2.2 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF16 PF01519.16 KNE01584.1 - 0.61 10.6 6.5 4.2 7.9 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 YabA PF06156.13 KNE01584.1 - 1.7 9.3 4.6 3.4 8.3 1.2 2.1 1 1 0 2 2 2 0 Initiation control protein YabA Med9 PF07544.13 KNE01584.1 - 1.9 8.6 7.5 1.2 9.2 2.5 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF2203 PF09969.9 KNE01584.1 - 2.5 8.8 5.3 8.2 7.2 1.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) GrpE PF01025.19 KNE01584.1 - 3.1 7.4 7.7 44 3.7 7.7 2.0 1 1 0 1 1 1 0 GrpE bZIP_1 PF00170.21 KNE01584.1 - 7.8 6.7 15.4 0.17 12.0 1.2 2.8 2 1 1 3 3 3 0 bZIP transcription factor Med31 PF05669.12 KNE01585.1 - 1.2e-38 131.0 2.1 1.4e-38 130.7 2.1 1.1 1 0 0 1 1 1 1 SOH1 Scs3p PF10261.9 KNE01586.1 - 3.2e-65 220.1 19.8 1.1e-64 218.3 19.8 1.7 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM He_PIG PF05345.12 KNE01587.1 - 5.1e-14 52.2 13.9 1.7e-06 28.1 1.1 4.0 4 0 0 4 4 4 3 Putative Ig domain DUF4448 PF14610.6 KNE01587.1 - 1.8e-05 24.6 0.0 4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 KNE01587.1 - 0.00012 22.0 0.3 0.00052 19.9 0.0 2.3 2 0 0 2 2 2 1 TMEM154 protein family Mid2 PF04478.12 KNE01587.1 - 0.0026 17.6 0.0 0.015 15.1 0.0 2.3 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor DUF5527 PF17665.1 KNE01587.1 - 0.028 14.0 0.0 0.09 12.3 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5527) FAM163 PF15069.6 KNE01587.1 - 0.13 12.7 0.1 0.72 10.3 0.1 2.2 1 1 1 2 2 2 0 FAM163 family Adeno_E3_CR2 PF02439.15 KNE01587.1 - 0.15 11.9 0.2 0.28 10.9 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Tweety PF04906.13 KNE01587.1 - 0.26 9.9 0.1 0.4 9.3 0.1 1.2 1 0 0 1 1 1 0 Tweety 4HBT PF03061.22 KNE01588.1 - 0.00016 22.0 1.3 0.66 10.4 0.1 2.8 2 1 0 2 2 2 2 Thioesterase superfamily DUF3888 PF13027.6 KNE01588.1 - 0.12 12.8 0.2 0.28 11.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3888) Transket_pyr PF02779.24 KNE01589.1 - 3.1e-45 154.0 0.0 4.7e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KNE01589.1 - 2.1e-37 127.7 0.1 4e-37 126.9 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Acatn PF13000.7 KNE01591.1 - 4.9e-191 636.0 18.2 1.2e-131 440.0 9.9 2.6 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 ubiquitin PF00240.23 KNE01592.1 - 5.7e-05 22.8 0.3 6.9e-05 22.5 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KNE01592.1 - 0.014 15.8 0.4 0.064 13.7 0.4 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD PF11976.8 KNE01592.1 - 0.029 14.2 0.3 0.034 14.0 0.3 1.1 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KNE01592.1 - 0.1 12.6 0.3 4.4 7.4 0.1 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain Metallophos PF00149.28 KNE01593.1 - 2.2e-32 113.2 0.7 3.2e-32 112.7 0.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Aminotran_3 PF00202.21 KNE01594.1 - 1.3e-115 386.3 0.1 1.7e-115 386.0 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III PrpR_N PF06506.11 KNE01594.1 - 0.055 13.0 0.8 0.71 9.4 0.0 2.6 3 0 0 3 3 3 0 Propionate catabolism activator IceA2 PF05862.11 KNE01594.1 - 0.11 12.4 0.2 17 5.5 0.0 2.7 2 0 0 2 2 2 0 Helicobacter pylori IceA2 protein Cation_efflux PF01545.21 KNE01595.1 - 7.3e-07 29.1 10.1 2.2e-06 27.5 10.1 1.9 1 1 0 1 1 1 1 Cation efflux family Med12 PF09497.10 KNE01596.1 - 1.4e-24 86.1 1.2 6.6e-24 84.0 0.3 2.5 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Myosin_head PF00063.21 KNE01597.1 - 1e-230 767.6 10.9 1.2e-230 767.3 10.9 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KNE01597.1 - 3.9e-47 160.4 0.0 7.5e-47 159.4 0.0 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding Hpr_kinase_C PF07475.12 KNE01597.1 - 0.00015 21.4 0.8 0.38 10.3 0.1 2.5 2 0 0 2 2 2 2 HPr Serine kinase C-terminal domain RsgA_GTPase PF03193.16 KNE01597.1 - 0.011 15.7 0.2 0.023 14.6 0.2 1.5 1 0 0 1 1 1 0 RsgA GTPase ExsD PF16806.5 KNE01597.1 - 0.032 14.2 0.6 0.084 12.8 0.6 1.7 1 0 0 1 1 1 0 Antiactivator protein ExsD AAA_16 PF13191.6 KNE01597.1 - 0.034 14.5 0.0 0.1 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 KNE01597.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SH3_1 PF00018.28 KNE01597.1 - 0.082 12.5 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 SH3 domain AAA_22 PF13401.6 KNE01597.1 - 0.1 12.9 0.0 0.34 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KNE01597.1 - 0.13 12.7 0.8 0.38 11.2 0.0 2.3 2 0 0 2 2 1 0 RNA helicase NACHT PF05729.12 KNE01597.1 - 0.15 11.9 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain IQ PF00612.27 KNE01597.1 - 0.54 10.2 12.2 2.7 8.0 4.0 2.6 1 1 1 2 2 2 0 IQ calmodulin-binding motif WD40 PF00400.32 KNE01598.1 - 7.8e-57 187.9 35.3 3e-09 37.3 0.1 9.1 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNE01598.1 - 7.1e-18 64.7 4.5 0.0012 19.1 0.1 5.9 2 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 KNE01598.1 - 1.6e-09 38.1 0.0 3.5e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 KNE01598.1 - 1.2e-06 27.7 1.7 0.24 10.3 0.0 4.7 4 2 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KNE01598.1 - 2.2e-06 26.6 7.7 0.071 11.7 0.1 5.2 3 2 2 5 5 5 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KNE01598.1 - 5.1e-05 23.2 0.3 0.011 15.6 0.0 3.4 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 KNE01598.1 - 0.0028 16.5 0.2 0.094 11.4 0.1 2.5 2 0 0 2 2 2 1 Nup133 N terminal like WD40_like PF17005.5 KNE01598.1 - 0.017 14.5 0.0 1.1 8.5 0.0 3.4 3 1 1 4 4 4 0 WD40-like domain Cytochrom_D1 PF02239.16 KNE01598.1 - 0.017 13.7 0.1 0.091 11.3 0.1 2.1 1 1 1 2 2 2 0 Cytochrome D1 heme domain Frtz PF11768.8 KNE01598.1 - 0.039 12.3 0.0 2.5 6.3 0.0 2.4 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz EcoEI_R_C PF08463.10 KNE01598.1 - 0.18 11.9 0.0 0.34 11.0 0.0 1.3 1 0 0 1 1 1 0 EcoEI R protein C-terminal PD40 PF07676.12 KNE01598.1 - 0.19 11.7 0.4 2.6 8.1 0.1 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat LRR_8 PF13855.6 KNE01599.1 - 2.7e-06 27.0 15.4 0.00039 20.1 4.5 4.5 2 2 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KNE01599.1 - 3e-06 27.5 3.2 3e-06 27.5 3.2 5.4 3 1 5 8 8 8 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KNE01599.1 - 2.4e-05 24.0 6.3 0.29 11.3 0.0 5.4 5 0 0 5 5 5 1 Leucine Rich repeat F-box_4 PF15966.5 KNE01599.1 - 0.0046 16.8 0.2 0.049 13.5 0.0 2.5 2 1 1 3 3 3 1 F-box F-box PF00646.33 KNE01599.1 - 0.035 14.0 2.0 0.071 13.0 0.3 2.5 2 0 0 2 2 2 0 F-box domain LRR_9 PF14580.6 KNE01599.1 - 2 7.9 5.7 0.82 9.2 0.5 2.6 2 1 2 4 4 4 0 Leucine-rich repeat DUF3362 PF11842.8 KNE01600.1 - 0.1 13.0 0.4 0.17 12.2 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3362) PsaL PF02605.15 KNE01600.1 - 0.18 11.5 0.0 1.3 8.7 0.0 2.2 1 1 1 2 2 2 0 Photosystem I reaction centre subunit XI Pkinase PF00069.25 KNE01601.1 - 1.9e-68 230.7 0.0 1.8e-67 227.5 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE01601.1 - 4.1e-37 127.9 0.6 3.1e-36 125.0 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KNE01601.1 - 2e-07 30.7 0.0 5.8e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KNE01601.1 - 0.0011 17.8 0.0 0.0022 16.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KNE01601.1 - 0.0012 18.9 0.1 0.0039 17.1 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KNE01601.1 - 0.0036 16.4 0.0 0.0083 15.2 0.0 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 FTA2 PF13095.6 KNE01601.1 - 0.06 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KNE01601.1 - 0.072 12.4 0.1 0.25 10.7 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Img2 PF05046.14 KNE01603.1 - 9.9e-19 67.4 0.3 1.4e-18 67.0 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) zf-C2H2 PF00096.26 KNE01604.1 - 1.3e-20 72.6 44.3 5.6e-05 23.4 1.3 8.2 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KNE01604.1 - 4.3e-12 45.9 58.3 1.8e-07 31.2 3.7 8.4 9 0 0 9 9 9 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KNE01604.1 - 6.8e-12 45.2 50.8 0.0038 17.9 0.7 8.9 8 0 0 8 8 8 5 C2H2-type zinc finger FOXP-CC PF16159.5 KNE01604.1 - 0.00017 22.1 37.1 0.2 12.3 0.3 7.1 4 3 3 7 7 7 3 FOXP coiled-coil domain zf-C2HC_2 PF13913.6 KNE01604.1 - 0.0014 18.5 5.9 3.9 7.5 0.2 4.2 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KNE01604.1 - 0.0036 17.0 0.2 0.0036 17.0 0.2 5.2 5 0 0 5 5 5 1 zinc-finger C2H2-type zf_ZIC PF18366.1 KNE01604.1 - 0.006 16.7 0.0 0.006 16.7 0.0 5.1 5 1 1 6 6 6 1 Zic proteins zinc finger domain zf-met PF12874.7 KNE01604.1 - 0.012 16.0 17.0 0.062 13.7 1.1 5.2 5 1 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KNE01604.1 - 0.015 15.5 22.2 0.015 15.5 0.2 6.5 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding DUF3268 PF11672.8 KNE01604.1 - 0.03 14.7 6.3 0.66 10.3 0.9 2.8 2 0 0 2 2 2 0 zinc-finger-containing domain PAT1 PF09770.9 KNE01607.1 - 1.1e-97 328.4 23.3 3.3e-56 191.1 0.8 3.0 2 1 1 3 3 3 3 Topoisomerase II-associated protein PAT1 Chorismate_bind PF00425.18 KNE01608.1 - 8.6e-72 241.8 0.0 1.2e-71 241.3 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 KNE01608.1 - 1.4e-33 116.3 0.0 2.4e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KNE01608.1 - 1.2e-16 61.2 0.0 2.4e-15 57.0 0.0 2.5 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KNE01608.1 - 4e-06 26.8 0.0 9.8e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 Uso1_p115_head PF04869.14 KNE01609.1 - 2.7e-79 266.5 0.1 2.7e-79 266.5 0.1 2.2 3 0 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, head region COG5 PF10392.9 KNE01609.1 - 0.001 19.3 7.7 0.001 19.3 7.7 3.5 1 1 2 3 3 3 1 Golgi transport complex subunit 5 HEAT_2 PF13646.6 KNE01609.1 - 0.0012 19.2 0.0 0.2 12.1 0.0 3.5 3 0 0 3 3 3 1 HEAT repeats RsgA_GTPase PF03193.16 KNE01609.1 - 0.23 11.4 2.2 0.54 10.1 2.2 1.6 1 0 0 1 1 1 0 RsgA GTPase HOOK PF05622.12 KNE01609.1 - 3.5 5.7 44.6 6 4.9 41.2 2.1 2 0 0 2 2 2 0 HOOK protein Cep57_MT_bd PF06657.13 KNE01609.1 - 3.7 8.1 22.6 1.1 9.8 2.8 4.8 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 IKI3 PF04762.12 KNE01610.1 - 1.8e-256 853.6 0.0 2.3e-256 853.3 0.0 1.1 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 KNE01610.1 - 0.0024 18.1 0.0 13 6.2 0.0 4.1 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain GHL13 PF14883.6 KNE01610.1 - 0.066 12.3 0.6 0.13 11.3 0.6 1.5 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 V_ATPase_I PF01496.19 KNE01611.1 - 4.7e-296 984.0 6.6 5.6e-296 983.8 6.6 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ISK_Channel PF02060.15 KNE01611.1 - 0.1 12.3 1.0 0.34 10.7 1.0 1.8 1 0 0 1 1 1 0 Slow voltage-gated potassium channel RIX1 PF08167.12 KNE01612.1 - 1.7e-18 67.0 2.5 5.5e-18 65.4 2.5 1.8 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis ANAPC5 PF12862.7 KNE01613.1 - 3.8e-25 87.8 3.5 4e-25 87.7 1.8 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 CDP-OH_P_transf PF01066.21 KNE01614.1 - 2.5e-13 50.6 0.7 2.5e-13 50.6 0.7 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase RCC1_2 PF13540.6 KNE01615.1 - 8.8e-16 57.3 4.0 6.9e-08 32.1 0.1 4.1 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 KNE01615.1 - 1.5e-13 51.1 0.5 0.022 15.3 0.0 5.6 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat F-box PF00646.33 KNE01615.1 - 0.00085 19.1 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain ORMDL PF04061.14 KNE01616.1 - 3.7e-54 182.2 3.9 4.5e-54 181.9 3.9 1.0 1 0 0 1 1 1 1 ORMDL family ATP-synt_Z PF16594.5 KNE01616.1 - 0.0076 15.7 0.1 0.016 14.7 0.1 1.5 1 0 0 1 1 1 1 Putative AtpZ or ATP-synthase-associated SHMT PF00464.19 KNE01617.1 - 4.9e-208 690.6 0.0 5.6e-208 690.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KNE01617.1 - 2.4e-05 23.7 0.0 5.9e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KNE01617.1 - 0.00048 19.5 0.0 0.001 18.4 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KNE01617.1 - 0.056 12.0 0.0 0.087 11.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KNE01617.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Hexokinase_2 PF03727.16 KNE01618.1 - 2.5e-70 236.7 0.0 3.3e-70 236.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KNE01618.1 - 3.8e-70 235.8 0.0 5.3e-70 235.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF4372 PF14294.6 KNE01618.1 - 0.12 12.6 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4372) DUF1769 PF08588.10 KNE01619.1 - 2.2e-17 63.0 0.2 3.6e-17 62.3 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) TAL_FSA PF00923.19 KNE01620.1 - 5.4e-98 327.9 1.2 6.2e-98 327.7 1.2 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Surface_Ag_2 PF01617.17 KNE01620.1 - 0.079 12.4 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Surface antigen Flavokinase PF01687.17 KNE01621.1 - 1.1e-25 90.1 0.0 1.4e-25 89.7 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase Mad3_BUB1_I PF08311.12 KNE01622.1 - 0.46 10.5 5.4 0.46 10.5 0.1 3.1 3 1 0 4 4 4 0 Mad3/BUB1 homology region 1 Ribosomal_L18A PF01775.17 KNE01623.1 - 1.5e-52 176.8 0.8 1.5e-52 176.8 0.8 1.5 1 1 1 2 2 2 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A FA_hydroxylase PF04116.13 KNE01624.1 - 4.3e-25 88.6 18.6 4.3e-25 88.6 18.6 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily GATase PF00117.28 KNE01625.1 - 6.7e-45 153.2 0.0 8.8e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 KNE01625.1 - 5.4e-44 149.1 0.0 8.7e-44 148.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 KNE01625.1 - 5.8e-05 22.9 0.3 0.0011 18.7 0.1 2.4 1 1 1 2 2 2 1 Peptidase C26 Bul1_N PF04425.12 KNE01626.1 - 6.6e-110 368.0 3.6 1.2e-109 367.1 3.6 1.3 1 0 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.12 KNE01626.1 - 1.3e-11 44.4 0.0 5.5e-09 35.8 0.0 2.6 1 1 0 2 2 2 2 Bul1 C terminus DWNN PF08783.11 KNE01627.1 - 2e-23 82.5 0.4 6.4e-23 80.8 0.0 2.1 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 KNE01627.1 - 1.2e-07 31.4 7.3 2.4e-07 30.5 7.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KNE01627.1 - 0.00011 22.1 2.0 0.00026 20.9 2.0 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KNE01627.1 - 0.016 15.2 0.5 0.06 13.3 0.4 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 KNE01627.1 - 0.047 13.4 0.2 0.12 12.1 0.2 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Zn_Tnp_IS1595 PF12760.7 KNE01627.1 - 0.32 11.0 3.2 1.8 8.6 0.0 2.7 3 0 0 3 3 3 0 Transposase zinc-ribbon domain eIF3g PF12353.8 KNE01627.1 - 2.3 8.6 6.0 0.98 9.8 0.4 2.8 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Nup160 PF11715.8 KNE01628.1 - 6.1e-22 78.0 2.0 2e-21 76.3 2.0 1.8 1 1 0 1 1 1 1 Nucleoporin Nup120/160 TAP42 PF04177.12 KNE01629.1 - 4.7e-72 242.8 4.5 5.3e-72 242.6 4.5 1.0 1 0 0 1 1 1 1 TAP42-like family TTSSLRR PF12468.8 KNE01629.1 - 0.069 13.4 0.2 0.15 12.3 0.2 1.6 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein HTH_16 PF12645.7 KNE01629.1 - 0.089 12.8 0.5 0.6 10.2 0.1 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain DUF4917 PF16263.5 KNE01629.1 - 0.11 11.8 1.1 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4917) TFIIA_gamma_C PF02751.14 KNE01630.1 - 1.2e-23 83.0 2.1 1.8e-23 82.4 2.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 KNE01630.1 - 6.1e-21 74.2 0.1 8.3e-21 73.8 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain HMG_box PF00505.19 KNE01633.1 - 2.3e-21 76.0 0.7 2.5e-21 75.8 0.7 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KNE01633.1 - 2.6e-13 50.4 0.4 2.9e-13 50.2 0.4 1.0 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 KNE01633.1 - 0.0039 17.1 1.0 0.005 16.8 1.0 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box 5 CHDNT PF08073.12 KNE01633.1 - 0.067 13.2 0.0 0.094 12.7 0.0 1.2 1 0 0 1 1 1 0 CHDNT (NUC034) domain CUE PF02845.16 KNE01634.1 - 9.5e-09 34.8 0.3 1.9e-08 33.8 0.3 1.6 1 0 0 1 1 1 1 CUE domain TTL PF03133.15 KNE01635.1 - 1.8e-58 198.0 0.6 3.1e-58 197.3 0.6 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 KNE01635.1 - 1.8e-45 155.1 0.0 2.8e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE zf-Tim10_DDP PF02953.15 KNE01636.1 - 7.5e-16 57.5 0.3 1e-15 57.1 0.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger F_bP_aldolase PF01116.20 KNE01637.1 - 1.5e-91 306.8 0.0 1.7e-91 306.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II SNAP PF14938.6 KNE01637.1 - 0.06 12.8 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP Peptidase_C26 PF07722.13 KNE01637.1 - 0.066 13.0 0.1 3.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Peptidase C26 Acetyltransf_1 PF00583.25 KNE01638.1 - 3.3e-16 59.6 0.1 4.9e-16 59.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KNE01638.1 - 6.8e-09 36.0 0.0 1.2e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KNE01638.1 - 1.5e-08 34.7 0.0 2.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KNE01638.1 - 3.7e-07 30.9 0.0 4.8e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KNE01638.1 - 2.1e-06 27.6 0.1 4.3e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KNE01638.1 - 0.00039 20.1 0.0 0.00065 19.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KNE01638.1 - 0.0006 19.9 0.0 0.0012 18.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain RXT2_N PF08595.11 KNE01639.1 - 1.2e-31 109.8 1.0 1.2e-31 109.8 1.0 1.9 2 0 0 2 2 2 1 RXT2-like, N-terminal SPACA9 PF15120.6 KNE01640.1 - 0.031 14.1 0.0 0.034 13.9 0.0 1.1 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 MFS_1 PF07690.16 KNE01644.1 - 1.7e-23 83.1 46.1 1.6e-18 66.8 32.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KNE01644.1 - 7.7e-08 31.6 7.2 0.00036 19.5 0.2 2.2 2 0 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 KNE01644.1 - 4.2e-06 25.9 14.5 0.0011 17.9 0.5 2.7 1 1 1 3 3 3 3 Sugar (and other) transporter DUF2530 PF10745.9 KNE01644.1 - 4.7 7.5 12.9 13 6.1 0.5 4.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) Acetyltransf_6 PF13480.7 KNE01645.1 - 2e-08 34.5 0.0 4.5e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2678 PF10856.8 KNE01645.1 - 0.4 10.6 5.3 0.33 10.9 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) CRAL_TRIO PF00650.20 KNE01648.1 - 3.8e-39 134.0 0.0 9.5e-39 132.7 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KNE01648.1 - 2e-06 27.8 0.4 1.7e-05 24.9 0.0 2.6 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KNE01648.1 - 0.0048 17.1 0.0 0.016 15.4 0.0 1.9 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain DEP PF00610.21 KNE01649.1 - 1e-14 54.3 0.1 2.6e-13 49.8 0.0 2.6 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.27 KNE01649.1 - 1.1e-11 44.8 0.1 3.8e-11 43.0 0.1 1.9 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 KNE01649.1 - 9.1e-10 38.7 0.7 2.9e-08 33.9 0.0 2.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Spore_IV_A PF09547.10 KNE01649.1 - 0.0021 17.1 1.9 0.0052 15.8 1.9 1.6 1 0 0 1 1 1 1 Stage IV sporulation protein A (spore_IV_A) DUF1487 PF07368.11 KNE01649.1 - 0.0093 15.4 2.3 1.7 8.1 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF1487) Na_Ca_ex_C PF16494.5 KNE01649.1 - 0.047 14.1 0.2 0.047 14.1 0.2 2.1 2 0 0 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain COX8 PF02285.15 KNE01649.1 - 0.36 10.8 1.4 3.3 7.6 0.0 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII BAG PF02179.16 KNE01649.1 - 1.4 9.4 6.5 6.5 7.3 0.0 4.3 5 1 0 5 5 5 0 BAG domain CCDC66 PF15236.6 KNE01654.1 - 0.11 12.4 1.6 0.22 11.4 1.6 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 ECH_1 PF00378.20 KNE01656.1 - 5.3e-17 62.0 0.0 6.4e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KNE01656.1 - 7.5e-11 42.1 0.0 9.7e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Complex1_51K PF01512.17 KNE01656.1 - 0.18 11.7 0.0 0.53 10.2 0.0 1.8 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit NPR3 PF03666.13 KNE01657.1 - 5.5e-119 398.0 12.1 3.3e-104 349.3 9.6 3.1 2 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 DUF2120 PF09893.9 KNE01657.1 - 4.6 7.3 9.4 17 5.5 6.3 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) MT0933_antitox PF14013.6 KNE01657.1 - 9.5 6.6 15.3 5.2 7.4 1.8 2.5 1 1 1 2 2 2 0 MT0933-like antitoxin protein PROCN PF08083.11 KNE01658.1 - 2.1e-220 731.5 8.1 3.6e-220 730.7 8.1 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KNE01658.1 - 1.2e-122 407.9 0.6 2.5e-122 406.9 0.6 1.6 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KNE01658.1 - 1.2e-83 278.9 3.0 1.3e-83 278.7 0.9 2.2 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KNE01658.1 - 3.8e-75 250.9 1.8 8.3e-75 249.8 1.8 1.6 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KNE01658.1 - 2.3e-73 244.6 0.0 5.4e-73 243.4 0.0 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 KNE01658.1 - 4.7e-45 152.5 0.0 1.2e-44 151.2 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 KNE01658.1 - 9.1e-45 150.9 0.1 5e-44 148.6 0.2 2.2 2 0 0 2 2 2 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 KNE01658.1 - 3.1e-06 27.2 0.0 9.1e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MMtag PF10159.9 KNE01658.1 - 0.11 12.8 0.1 0.35 11.2 0.1 1.9 1 0 0 1 1 1 0 Multiple myeloma tumor-associated TPD PF14811.6 KNE01658.1 - 0.11 12.4 1.2 0.6 10.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function TPD sequence-motif zf-C3HC4_3 PF13920.6 KNE01663.1 - 1.3e-07 31.3 13.6 2.1e-07 30.7 13.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KNE01663.1 - 1.4 8.9 12.0 2.5 8.1 12.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 MIG-14_Wnt-bd PF06664.12 KNE01664.1 - 0.014 14.7 0.0 0.016 14.4 0.0 1.0 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Aminotran_1_2 PF00155.21 KNE01665.1 - 5.3e-36 124.5 0.0 7.1e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II ANAPC8 PF04049.13 KNE01666.1 - 1.8e-23 83.1 5.8 1.1e-21 77.4 4.4 2.9 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.6 KNE01666.1 - 4.8e-20 70.0 15.5 2.4e-05 24.2 0.1 7.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 KNE01666.1 - 3.2e-19 67.9 20.0 3.5e-05 23.4 0.0 7.2 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 KNE01666.1 - 5.2e-14 51.1 25.8 0.00016 21.5 0.0 8.9 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 KNE01666.1 - 5.5e-13 48.4 3.5 1e-07 31.5 0.1 4.8 4 1 1 5 5 5 3 TPR repeat TPR_14 PF13428.6 KNE01666.1 - 3.3e-10 39.9 8.8 0.0042 17.8 0.0 7.6 7 2 2 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 KNE01666.1 - 1.1e-06 29.1 13.7 6.5e-05 23.5 0.0 6.4 7 1 1 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KNE01666.1 - 1.5e-06 28.4 27.0 0.097 12.9 1.6 6.2 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KNE01666.1 - 0.0001 22.1 0.1 0.54 10.4 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KNE01666.1 - 0.00042 20.5 21.9 0.13 12.6 1.5 6.8 5 1 2 7 7 7 2 Tetratricopeptide repeat ChAPs PF09295.10 KNE01666.1 - 0.0006 18.9 1.6 3.1 6.7 0.0 3.5 3 1 1 4 4 4 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 KNE01666.1 - 0.00074 20.0 9.0 1.2 9.7 0.0 5.4 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KNE01666.1 - 0.002 18.3 0.3 0.3 11.2 0.0 2.9 1 1 0 2 2 2 1 Tetratricopeptide repeat Fungal_trans_2 PF11951.8 KNE01666.1 - 0.0026 16.7 0.6 0.16 10.8 0.3 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain TPR_6 PF13174.6 KNE01666.1 - 0.0026 18.3 16.7 13 6.7 0.0 8.3 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_17 PF13431.6 KNE01666.1 - 0.0044 17.3 7.8 0.48 10.9 0.1 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat DUF3856 PF12968.7 KNE01666.1 - 0.047 13.7 3.1 0.86 9.7 0.2 3.4 2 1 2 4 4 4 0 Domain of Unknown Function (DUF3856) PAP_central PF04928.17 KNE01666.1 - 0.054 12.5 0.0 0.063 12.2 0.0 1.3 1 0 0 1 1 1 0 Poly(A) polymerase central domain PX PF00787.24 KNE01667.1 - 0.016 15.2 2.3 0.065 13.2 2.3 1.8 1 1 0 1 1 1 0 PX domain DASH_Hsk3 PF08227.11 KNE01667.1 - 9 6.8 6.9 1.2 9.6 0.3 2.6 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like MPC PF03650.13 KNE01668.1 - 3.4e-47 159.1 0.1 3.9e-47 158.9 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers ABC_membrane PF00664.23 KNE01669.1 - 1.5e-63 215.0 32.8 1.1e-34 120.4 13.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KNE01669.1 - 1.5e-52 177.7 0.0 2.2e-30 105.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KNE01669.1 - 3.1e-13 49.7 6.9 0.00046 19.7 0.4 4.3 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KNE01669.1 - 5.7e-07 29.6 0.4 0.036 14.1 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KNE01669.1 - 8.8e-06 25.4 0.2 0.14 12.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KNE01669.1 - 0.00018 21.5 0.1 0.88 9.5 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase DUF87 PF01935.17 KNE01669.1 - 0.00049 20.3 0.3 0.097 12.8 0.0 2.8 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 KNE01669.1 - 0.00063 20.0 0.0 0.63 10.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.6 KNE01669.1 - 0.00078 20.0 0.3 1.6 9.1 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 KNE01669.1 - 0.002 18.6 0.1 1.3 9.4 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KNE01669.1 - 0.0021 17.3 0.9 0.73 9.0 0.2 3.3 3 1 0 3 3 3 1 NB-ARC domain NACHT PF05729.12 KNE01669.1 - 0.0032 17.4 0.1 0.48 10.3 0.0 3.3 3 0 0 3 3 3 1 NACHT domain AAA_21 PF13304.6 KNE01669.1 - 0.0048 16.8 0.1 4.8 6.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KNE01669.1 - 0.012 15.3 0.5 4.9 6.7 0.0 2.6 3 0 0 3 3 2 0 AAA ATPase domain AIG1 PF04548.16 KNE01669.1 - 0.02 14.2 0.9 0.93 8.8 0.1 2.4 2 0 0 2 2 2 0 AIG1 family AAA_7 PF12775.7 KNE01669.1 - 0.021 14.4 0.0 4.7 6.7 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KNE01669.1 - 0.025 13.9 0.2 4.6 6.5 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 KNE01669.1 - 0.039 14.0 0.0 4.7 7.2 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KNE01669.1 - 0.043 13.0 0.2 0.51 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Dynamin_N PF00350.23 KNE01669.1 - 0.044 13.8 3.9 2.3 8.2 0.1 2.9 3 0 0 3 3 2 0 Dynamin family AAA_30 PF13604.6 KNE01669.1 - 0.061 13.0 0.2 16 5.2 0.0 2.9 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KNE01669.1 - 0.075 12.9 0.1 0.48 10.3 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea FtsK_SpoIIIE PF01580.18 KNE01669.1 - 0.079 12.3 0.2 6.2 6.1 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family DnaB_C PF03796.15 KNE01669.1 - 0.085 12.2 0.0 6.7 6.0 0.0 3.3 4 0 0 4 4 4 0 DnaB-like helicase C terminal domain AAA PF00004.29 KNE01669.1 - 0.095 13.1 0.1 11 6.4 0.0 3.4 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 KNE01669.1 - 0.11 11.5 0.0 6.4 5.7 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KNE01669.1 - 0.11 12.1 0.3 2.5 7.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KNE01669.1 - 0.15 12.3 0.2 15 5.8 0.0 3.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Aconitase PF00330.20 KNE01672.1 - 4e-152 507.4 0.0 5e-152 507.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KNE01672.1 - 4.2e-45 153.3 0.0 8.2e-45 152.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Spermine_synth PF01564.17 KNE01673.1 - 5.9e-75 250.8 0.0 8.4e-75 250.3 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KNE01673.1 - 1.2e-22 79.5 0.0 2e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KNE01673.1 - 0.0012 19.5 0.0 0.0024 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNE01673.1 - 0.0025 18.5 0.0 0.0046 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain XPA_C PF05181.12 KNE01674.1 - 1.8e-20 72.6 0.1 3.5e-20 71.7 0.1 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 KNE01674.1 - 4e-05 23.6 1.6 4e-05 23.6 1.6 2.4 3 0 0 3 3 3 1 XPA protein N-terminal Clathrin_lg_ch PF01086.17 KNE01674.1 - 0.011 15.8 6.9 0.025 14.6 0.3 2.1 2 0 0 2 2 2 0 Clathrin light chain zf-RanBP PF00641.18 KNE01674.1 - 0.64 9.4 6.4 1.9 7.9 0.1 2.8 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others Zn_Tnp_IS1595 PF12760.7 KNE01674.1 - 1.6 8.8 6.4 1.2 9.2 2.4 2.6 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Glyco_hydro_65N PF03636.15 KNE01675.1 - 0.031 13.9 0.1 0.036 13.7 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain HSP90 PF00183.18 KNE01677.1 - 7.5e-224 744.4 38.7 1e-223 744.0 38.7 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KNE01677.1 - 8.6e-15 55.2 0.0 1.7e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KNE01677.1 - 2e-09 37.4 0.0 6.8e-09 35.7 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cofac_haem_bdg PF04187.13 KNE01677.1 - 0.1 12.6 0.1 0.34 10.8 0.1 1.9 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN DUF2052 PF09747.9 KNE01677.1 - 3.4 7.7 21.6 2.2 8.4 13.7 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) RTP1_C1 PF10363.9 KNE01678.1 - 7.9e-33 113.0 3.6 1.5e-30 105.6 0.1 3.6 4 0 0 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 KNE01678.1 - 5.8e-11 41.9 2.2 2e-10 40.2 2.2 2.0 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 PMC2NT PF08066.12 KNE01678.1 - 0.1 13.3 8.2 0.059 14.1 3.6 2.9 2 1 1 3 3 3 0 PMC2NT (NUC016) domain RIX1 PF08167.12 KNE01678.1 - 0.26 11.0 1.8 10 5.8 0.2 2.7 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis BP28CT PF08146.12 KNE01678.1 - 1 9.2 5.0 0.38 10.6 1.4 2.1 3 0 0 3 3 3 0 BP28CT (NUC211) domain Ank_2 PF12796.7 KNE01679.1 - 8.8e-28 96.7 4.8 1.6e-14 54.2 0.4 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KNE01679.1 - 1.7e-15 56.8 0.7 2.2e-08 34.2 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KNE01679.1 - 2.9e-14 53.2 0.2 2.8e-13 50.1 0.1 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KNE01679.1 - 2.5e-12 45.8 0.2 1.2e-05 25.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KNE01679.1 - 4.4e-11 42.7 0.2 3.3e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat DUF4974 PF16344.5 KNE01679.1 - 0.03 14.3 0.2 0.053 13.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) LRAT PF04970.13 KNE01679.1 - 0.03 14.6 0.8 0.059 13.7 0.7 1.6 1 1 0 1 1 1 0 Lecithin retinol acyltransferase DUF2430 PF10353.9 KNE01679.1 - 0.14 12.6 0.2 0.88 10.0 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2430) AFT PF08731.11 KNE01679.1 - 0.36 11.2 2.4 0.59 10.6 2.4 1.3 1 0 0 1 1 1 0 Transcription factor AFT YebF PF13995.6 KNE01680.1 - 0.068 13.2 0.1 0.077 13.0 0.1 1.0 1 0 0 1 1 1 0 YebF-like protein eIF-5_eIF-2B PF01873.17 KNE01682.1 - 5.6e-39 132.6 0.0 8.6e-39 132.0 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 IF2_N PF04760.15 KNE01682.1 - 0.024 14.4 0.0 0.081 12.8 0.0 1.8 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region GET2 PF08690.10 KNE01682.1 - 0.047 13.4 1.8 0.066 12.9 1.8 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 zf-HYPF PF07503.12 KNE01682.1 - 0.07 12.9 0.1 17 5.2 0.0 2.6 2 0 0 2 2 2 0 HypF finger TF_Zn_Ribbon PF08271.12 KNE01682.1 - 0.1 12.1 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding DUF2752 PF10825.8 KNE01682.1 - 0.13 12.4 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) zinc_ribbon_6 PF14599.6 KNE01682.1 - 0.38 10.8 1.8 2 8.5 0.1 2.3 2 0 0 2 2 2 0 Zinc-ribbon Ecm29 PF13001.7 KNE01683.1 - 0.038 12.7 0.3 0.048 12.3 0.3 1.1 1 0 0 1 1 1 0 Proteasome stabiliser Pkinase PF00069.25 KNE01684.1 - 8.7e-38 130.2 0.0 1.1e-24 87.3 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNE01684.1 - 8e-15 54.8 0.0 5e-14 52.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KNE01684.1 - 0.054 13.4 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Med9 PF07544.13 KNE01685.1 - 6.6e-21 74.2 0.5 1e-20 73.6 0.5 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 GspL_C PF12693.7 KNE01685.1 - 0.016 15.0 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 GspL periplasmic domain GvpG PF05120.12 KNE01685.1 - 0.019 15.0 2.0 0.067 13.2 0.9 2.3 1 1 1 2 2 2 0 Gas vesicle protein G Rhomboid PF01694.22 KNE01686.1 - 3.3e-11 43.4 10.8 3.3e-11 43.4 10.8 1.4 2 0 0 2 2 2 1 Rhomboid family Inp1 PF12634.7 KNE01687.1 - 1.1e-18 67.6 0.0 3.7e-18 65.9 0.0 2.0 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 Porin_3 PF01459.22 KNE01688.1 - 9.9e-54 182.6 1.0 1.2e-53 182.3 1.0 1.1 1 0 0 1 1 1 1 Eukaryotic porin PFK PF00365.20 KNE01690.1 - 1.4e-183 608.7 2.7 1.3e-104 349.6 2.4 2.1 2 0 0 2 2 2 2 Phosphofructokinase SHOCT PF09851.9 KNE01690.1 - 0.0058 16.3 0.3 0.019 14.7 0.0 2.0 2 0 0 2 2 2 1 Short C-terminal domain Glyoxalase PF00903.25 KNE01690.1 - 0.011 16.0 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DAGK_cat PF00781.24 KNE01690.1 - 0.048 13.3 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain TBCC PF07986.12 KNE01691.1 - 1e-13 51.1 0.0 1.8e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C PDEase_II PF02112.15 KNE01691.1 - 0.069 12.2 0.2 0.093 11.8 0.2 1.1 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Ribosomal_S17 PF00366.20 KNE01691.1 - 0.18 11.9 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S17 TPP_enzyme_N PF02776.18 KNE01692.1 - 2.6e-22 79.2 0.0 5.1e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KNE01692.1 - 1.6e-18 66.9 0.0 3e-16 59.6 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KNE01692.1 - 1.1e-07 31.6 0.0 2.6e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain AMP-binding PF00501.28 KNE01693.1 - 4.2e-66 223.3 0.0 1.6e-64 218.0 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme TIP49 PF06068.13 KNE01694.1 - 4.1e-156 519.6 2.7 5.1e-156 519.3 2.7 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KNE01694.1 - 8.9e-22 77.0 0.7 3.4e-21 75.2 0.5 2.1 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 KNE01694.1 - 2.3e-08 34.5 1.5 8.1e-05 23.1 0.1 3.0 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KNE01694.1 - 1.9e-06 27.7 0.5 0.009 15.8 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 KNE01694.1 - 0.00062 19.2 0.1 0.0015 18.0 0.1 1.6 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_19 PF13245.6 KNE01694.1 - 0.00062 20.1 0.2 0.0035 17.7 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KNE01694.1 - 0.00071 19.9 0.1 0.1 12.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KNE01694.1 - 0.0011 19.4 2.4 0.0023 18.3 0.4 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KNE01694.1 - 0.0041 16.7 1.0 0.011 15.3 0.2 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KNE01694.1 - 0.0048 17.1 0.2 0.015 15.5 0.1 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KNE01694.1 - 0.0074 15.7 0.9 0.1 12.0 0.3 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KNE01694.1 - 0.018 15.0 0.1 1.4 8.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KNE01694.1 - 0.1 12.1 0.3 0.56 9.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP-synt_C PF00137.21 KNE01695.1 - 1.2e-29 102.4 30.3 2.1e-19 69.6 9.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.8 KNE01695.1 - 3.1 7.5 7.5 3.2 7.5 0.5 2.4 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain Mis14 PF08641.12 KNE01696.1 - 4.4e-26 91.8 4.9 4.4e-26 91.8 4.9 1.6 2 0 0 2 2 2 1 Kinetochore protein Mis14 like MIOX PF05153.15 KNE01696.1 - 0.0037 16.9 0.0 0.0075 15.9 0.0 1.5 1 0 0 1 1 1 1 Myo-inositol oxygenase APC_N_CC PF16689.5 KNE01696.1 - 0.017 15.2 2.1 0.074 13.1 0.3 2.7 1 1 1 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain ADIP PF11559.8 KNE01696.1 - 0.059 13.5 9.3 0.81 9.8 2.6 2.3 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding LMBR1 PF04791.16 KNE01696.1 - 0.088 11.7 5.2 0.098 11.5 5.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HD_2 PF12917.7 KNE01696.1 - 0.24 11.2 5.8 0.21 11.3 0.3 2.7 2 1 1 3 3 3 0 HD containing hydrolase-like enzyme Enkurin PF13864.6 KNE01696.1 - 3 8.3 9.8 1.9 9.0 6.4 2.2 1 1 1 2 2 2 0 Calmodulin-binding RasGAP_C PF03836.15 KNE01697.1 - 7.8e-37 126.5 8.2 7.8e-37 126.5 8.2 3.2 3 0 0 3 3 3 1 RasGAP C-terminus RasGAP PF00616.19 KNE01697.1 - 6.7e-33 114.2 2.1 6.7e-33 114.2 2.1 2.4 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.31 KNE01697.1 - 3.5e-09 36.8 0.2 2.3e-08 34.2 0.1 2.5 2 0 0 2 2 2 1 Calponin homology (CH) domain CAAP1 PF15335.6 KNE01697.1 - 0.81 10.3 7.6 0.14 12.8 1.3 3.1 3 0 0 3 3 3 0 Caspase activity and apoptosis inhibitor 1 IQ PF00612.27 KNE01697.1 - 2.2 8.3 27.7 6.8 6.8 0.0 9.6 12 0 0 12 12 12 0 IQ calmodulin-binding motif WD40_4 PF16300.5 KNE01698.1 - 6.2e-22 77.2 0.1 1.4e-21 76.1 0.1 1.6 1 0 0 1 1 1 1 Type of WD40 repeat zf-C2H2_4 PF13894.6 KNE01699.1 - 0.0086 16.8 0.8 0.026 15.3 0.3 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KNE01699.1 - 0.015 15.0 0.2 0.098 12.4 0.0 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KNE01699.1 - 0.045 14.0 0.4 0.12 12.7 0.1 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KNE01699.1 - 0.067 13.6 0.3 0.14 12.6 0.0 1.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KNE01699.1 - 0.16 12.5 0.2 0.16 12.5 0.2 1.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type OrsD PF12013.8 KNE01699.1 - 0.35 11.3 1.7 0.34 11.4 0.3 1.7 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-H2C2_2 PF13465.6 KNE01699.1 - 0.46 11.0 1.9 1.2 9.7 0.6 2.1 2 0 0 2 2 2 0 Zinc-finger double domain LCAT PF02450.15 KNE01700.1 - 4.9e-113 378.2 0.0 6.1e-113 377.9 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF915 PF06028.11 KNE01700.1 - 0.0091 15.4 0.7 0.46 9.8 0.5 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF900 PF05990.12 KNE01700.1 - 0.089 12.3 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 KNE01700.1 - 0.1 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF1749 PF08538.10 KNE01700.1 - 0.12 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Spore_III_AB PF09548.10 KNE01700.1 - 0.13 12.4 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) LIDHydrolase PF10230.9 KNE01700.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Autophagy_N PF03986.13 KNE01701.1 - 5.2e-45 152.8 0.5 8.3e-45 152.1 0.5 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 KNE01701.1 - 4.1e-15 55.0 0.3 9.8e-15 53.8 0.3 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 KNE01701.1 - 5.1e-14 52.6 0.0 1e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Stevor PF17410.2 KNE01701.1 - 0.3 10.6 0.9 0.37 10.3 0.2 1.4 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Whi5 PF08528.11 KNE01702.1 - 0.023 14.3 5.6 0.048 13.3 5.6 1.6 1 0 0 1 1 1 0 Whi5 like Aldo_ket_red PF00248.21 KNE01703.1 - 8e-40 136.9 0.0 8.5e-39 133.5 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family ERG2_Sigma1R PF04622.12 KNE01705.1 - 8.9e-88 293.1 0.2 1.1e-87 292.8 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein MatE PF01554.18 KNE01707.1 - 6.3e-59 198.2 38.5 1.6e-37 128.7 8.9 2.4 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KNE01707.1 - 0.00032 20.8 7.7 0.00032 20.8 7.7 4.4 2 2 2 4 4 4 2 Polysaccharide biosynthesis C-terminal domain YkyA PF10368.9 KNE01708.1 - 0.0067 16.1 3.4 0.009 15.7 3.4 1.1 1 0 0 1 1 1 1 Putative cell-wall binding lipoprotein TPR_MLP1_2 PF07926.12 KNE01708.1 - 0.022 14.8 2.4 0.022 14.8 2.4 1.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Cyclin_N PF00134.23 KNE01710.1 - 1.3e-30 105.7 0.1 2.5e-30 104.8 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Rot1 PF10681.9 KNE01714.1 - 3.1e-92 307.8 0.1 3.6e-92 307.6 0.1 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal VHS PF00790.19 KNE01715.1 - 6.4e-29 100.6 0.2 1.2e-28 99.7 0.2 1.5 1 0 0 1 1 1 1 VHS domain FYVE PF01363.21 KNE01715.1 - 3e-18 65.7 2.2 5.9e-18 64.8 2.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 KNE01715.1 - 0.00047 19.9 4.0 0.00047 19.9 4.0 3.0 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.16 KNE01715.1 - 0.046 13.9 1.3 0.16 12.2 1.3 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_2 PF13639.6 KNE01715.1 - 0.11 12.9 5.0 0.32 11.4 5.0 1.8 1 0 0 1 1 1 0 Ring finger domain SBP PF03110.14 KNE01715.1 - 0.12 12.7 1.6 0.26 11.6 1.6 1.5 1 0 0 1 1 1 0 SBP domain zf-AN1 PF01428.16 KNE01715.1 - 0.26 11.5 6.3 0.69 10.1 6.3 1.7 1 0 0 1 1 1 0 AN1-like Zinc finger OAD_gamma PF04277.13 KNE01715.1 - 1.6 9.4 6.5 1 10.0 1.4 2.5 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Orn_Arg_deC_N PF02784.16 KNE01716.1 - 5.6e-74 248.6 0.0 7e-74 248.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KNE01716.1 - 7.8e-17 61.3 0.0 1.1e-16 60.8 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 KNE01716.1 - 0.01 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Ala_racemase_N PF01168.20 KNE01716.1 - 0.01 15.5 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain Metallophos PF00149.28 KNE01718.1 - 1.4e-34 120.4 0.0 2.6e-34 119.5 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Hid1 PF12722.7 KNE01720.1 - 5.6e-158 527.6 6.6 6.4e-158 527.4 6.6 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KNE01720.1 - 2.1e-25 89.2 6.6 3.6e-25 88.5 6.6 1.3 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein WGG PF10273.9 KNE01721.1 - 7e-25 87.5 1.2 7e-25 87.5 1.2 1.6 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 ORC_WH_C PF18137.1 KNE01721.1 - 0.064 13.3 1.6 0.075 13.1 0.8 1.5 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal DUF1764 PF08576.10 KNE01721.1 - 0.088 13.7 4.1 5.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) AAA PF00004.29 KNE01722.1 - 3.1e-16 60.0 0.0 1e-15 58.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KNE01722.1 - 4.2e-15 55.7 0.1 1.3e-14 54.1 0.1 1.9 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 KNE01722.1 - 4e-10 40.3 0.0 7.4e-09 36.2 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KNE01722.1 - 1.3e-09 38.4 0.0 3.1e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain BAH PF01426.18 KNE01722.1 - 6.9e-06 25.9 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 BAH domain Cdc6_C PF09079.11 KNE01722.1 - 0.00047 20.1 0.1 0.0016 18.4 0.1 2.0 1 1 0 1 1 1 1 CDC6, C terminal winged helix domain ATPase_2 PF01637.18 KNE01722.1 - 0.00052 20.0 0.1 0.12 12.2 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NACHT PF05729.12 KNE01722.1 - 0.001 19.0 0.0 0.0042 17.0 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.6 KNE01722.1 - 0.0011 19.4 0.3 0.0047 17.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KNE01722.1 - 0.0084 16.7 0.0 0.026 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 KNE01722.1 - 0.02 14.1 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase NTPase_1 PF03266.15 KNE01722.1 - 0.049 13.6 0.2 0.13 12.1 0.2 1.7 1 0 0 1 1 1 0 NTPase Ras PF00071.22 KNE01723.1 - 6.8e-26 90.8 0.1 7.9e-26 90.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNE01723.1 - 4.1e-17 62.5 0.1 6e-17 62.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNE01723.1 - 0.00088 18.8 0.1 0.001 18.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KNE01723.1 - 0.00091 18.6 0.2 0.0012 18.3 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Choline_transpo PF04515.12 KNE01725.1 - 0.0096 15.2 0.1 0.011 14.9 0.1 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter Ribosomal_S3Ae PF01015.18 KNE01726.1 - 3.4e-85 284.7 3.5 4.1e-85 284.4 3.5 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 KNE01726.1 - 0.068 13.7 0.2 0.21 12.1 0.0 1.9 2 0 0 2 2 2 0 Translation initiation factor SUI1 C2 PF00168.30 KNE01727.1 - 1.7e-67 224.2 0.1 5.4e-21 74.8 0.0 5.4 5 0 0 5 5 5 5 C2 domain NT-C2 PF10358.9 KNE01727.1 - 0.058 13.1 0.2 2 8.1 0.0 3.3 3 0 0 3 3 3 0 N-terminal C2 in EEIG1 and EHBP1 proteins Macoilin PF09726.9 KNE01727.1 - 4.5 5.7 4.7 0.41 9.1 0.0 1.5 2 0 0 2 2 2 0 Macoilin family FKBP_C PF00254.28 KNE01729.1 - 4.6e-28 97.4 0.1 4.6e-28 97.4 0.1 2.3 3 0 0 3 3 3 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 KNE01729.1 - 4.7e-22 78.5 11.6 4.7e-22 78.5 11.6 3.1 2 2 0 2 2 1 1 Nucleoplasmin-like domain GAGA_bind PF06217.12 KNE01729.1 - 0.13 12.6 23.9 0.27 11.5 3.1 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family DUF4045 PF13254.6 KNE01729.1 - 0.24 11.0 30.8 0.85 9.2 14.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) DUF4604 PF15377.6 KNE01729.1 - 0.28 11.6 57.7 1.1 9.7 18.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) AAA_11 PF13086.6 KNE01729.1 - 0.52 10.0 25.8 0.056 13.2 2.4 2.1 2 0 0 2 2 2 0 AAA domain CCSAP PF15748.5 KNE01729.1 - 1.2 9.3 36.7 2.5 8.2 18.4 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 KNE01729.1 - 1.8 8.3 50.4 2.3 8.0 15.9 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KNE01729.1 - 3.4 6.3 30.0 2.2 6.9 7.3 2.1 2 0 0 2 2 2 0 Presenilin FAM60A PF15396.6 KNE01729.1 - 5.1 7.1 29.2 0.66 9.9 4.6 2.3 2 0 0 2 2 2 0 Protein Family FAM60A SOBP PF15279.6 KNE01729.1 - 9.6 6.7 9.4 1.7 9.1 4.2 1.9 2 0 0 2 2 2 0 Sine oculis-binding protein Xan_ur_permease PF00860.20 KNE01731.1 - 5.3e-71 239.4 27.5 7.5e-71 238.9 27.5 1.1 1 0 0 1 1 1 1 Permease family LptF_LptG PF03739.14 KNE01731.1 - 0.011 14.6 0.3 0.04 12.8 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG Peptidase_M48_N PF16491.5 KNE01731.1 - 0.044 13.7 0.5 0.72 9.7 0.0 2.9 3 0 0 3 3 3 0 CAAX prenyl protease N-terminal, five membrane helices She9_MDM33 PF05546.11 KNE01732.1 - 9.2e-83 276.9 12.1 1.6e-82 276.1 12.1 1.4 1 0 0 1 1 1 1 She9 / Mdm33 family HrpF PF06266.12 KNE01732.1 - 0.033 14.5 2.0 1.9 8.8 0.0 3.0 3 0 0 3 3 3 0 HrpF protein Cucumopine_C PF18631.1 KNE01732.1 - 0.057 13.4 0.2 0.32 11.0 0.1 2.1 2 0 0 2 2 2 0 Cucumopine synthase C-terminal helical bundle domain FliJ PF02050.16 KNE01732.1 - 0.13 12.5 12.0 0.15 12.3 0.2 3.7 3 1 0 3 3 3 0 Flagellar FliJ protein IZUMO PF15005.6 KNE01732.1 - 6 7.4 8.0 0.91 10.0 3.0 2.1 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated DRY_EERY PF09750.9 KNE01732.1 - 6 7.1 8.4 4.2 7.6 5.7 2.0 1 1 1 2 2 2 0 Alternative splicing regulator OEP PF02321.18 KNE01732.1 - 6.6 6.5 13.6 4.7 7.0 1.8 3.0 3 1 0 3 3 3 0 Outer membrane efflux protein PI-PLC-X PF00388.19 KNE01733.1 - 3.6e-17 62.3 0.0 6e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Ribonuc_red_sm PF00268.21 KNE01740.1 - 3.3e-122 407.3 2.2 4.3e-122 406.9 2.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 KNE01740.1 - 0.12 13.2 0.3 0.32 11.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4744) Nop10p PF04135.12 KNE01741.1 - 0.06 13.4 0.1 0.092 12.8 0.1 1.3 1 0 0 1 1 1 0 Nucleolar RNA-binding protein, Nop10p family Ribo_biogen_C PF04034.13 KNE01742.1 - 5.9e-50 168.3 0.0 8.8e-50 167.7 0.0 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KNE01742.1 - 3.4e-16 58.8 0.5 5.7e-16 58.0 0.5 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Hydantoinase_B PF02538.14 KNE01745.1 - 3.4e-209 695.6 0.0 4.3e-209 695.2 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KNE01745.1 - 2.3e-95 319.2 0.0 7e-95 317.6 0.0 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KNE01745.1 - 3e-51 173.7 0.1 6.7e-50 169.2 0.1 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region VPS9 PF02204.18 KNE01746.1 - 1.2e-10 41.6 0.0 7.8e-10 38.9 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.7 KNE01746.1 - 7.9e-06 26.4 1.2 0.13 12.9 0.0 4.2 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KNE01746.1 - 0.00029 21.1 1.0 0.019 15.3 0.1 3.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) ZapB PF06005.12 KNE01746.1 - 0.048 14.1 2.7 0.22 12.0 2.7 2.1 1 0 0 1 1 1 0 Cell division protein ZapB SGTA_dimer PF16546.5 KNE01747.1 - 2.5e-21 75.2 1.6 2.5e-21 75.2 1.6 1.7 2 0 0 2 2 2 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 KNE01747.1 - 5e-15 54.6 4.5 0.00018 21.2 0.7 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KNE01747.1 - 4.5e-12 45.1 5.3 0.00074 19.5 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KNE01747.1 - 1.4e-11 43.8 3.1 5.2e-05 22.9 0.1 3.2 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.6 KNE01747.1 - 4e-08 33.1 1.0 0.002 18.4 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KNE01747.1 - 4e-07 30.6 3.8 0.00037 21.1 2.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KNE01747.1 - 2.5e-06 27.3 12.3 0.009 16.2 0.8 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KNE01747.1 - 6e-06 25.9 0.1 2.1 8.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KNE01747.1 - 1e-05 25.9 1.8 0.52 11.3 0.2 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KNE01747.1 - 1.7e-05 25.2 2.8 0.023 15.2 1.3 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.17 KNE01747.1 - 5.4e-05 23.7 2.3 0.0019 18.6 2.3 2.4 1 1 0 1 1 1 1 Bacterial transcriptional activator domain STI1 PF17830.1 KNE01747.1 - 0.00042 20.2 6.5 0.00073 19.4 3.3 2.3 2 0 0 2 2 2 1 STI1 domain TPR_10 PF13374.6 KNE01747.1 - 0.00085 19.1 4.4 0.19 11.6 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KNE01747.1 - 0.0088 16.2 0.1 0.083 13.0 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KNE01747.1 - 0.014 15.7 4.9 0.93 9.8 2.6 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 KNE01747.1 - 0.024 13.9 1.6 0.39 9.9 2.1 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 KNE01747.1 - 2.1 8.7 4.9 1.5 9.2 0.9 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KNE01747.1 - 3.5 8.5 9.4 1.8 9.4 2.4 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat Kinesin PF00225.23 KNE01748.1 - 3.2e-110 368.2 0.0 8e-110 366.9 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KNE01748.1 - 3.7e-23 82.1 0.0 1.9e-22 79.8 0.0 2.3 1 0 0 1 1 1 1 Microtubule binding PilS PF08805.11 KNE01748.1 - 0.13 12.1 0.0 27 4.6 0.0 2.6 2 0 0 2 2 2 0 PilS N terminal Borrelia_REV PF03978.13 KNE01748.1 - 0.15 12.0 4.2 0.19 11.6 1.4 2.4 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein DUF5406 PF17400.2 KNE01748.1 - 0.29 11.6 3.6 1.8 9.0 0.0 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5406) Med9 PF07544.13 KNE01748.1 - 0.38 10.9 6.4 11 6.2 1.7 3.1 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF1509 PF07420.11 KNE01749.1 - 6.6 5.6 8.0 0.55 9.1 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1509) HisG PF01634.18 KNE01752.1 - 0.18 11.8 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 ATP phosphoribosyltransferase Sel1 PF08238.12 KNE01753.1 - 1.3e-39 133.7 24.7 2.2e-07 31.3 0.5 8.2 8 0 0 8 8 8 7 Sel1 repeat UQ_con PF00179.26 KNE01755.1 - 2.5e-21 75.8 0.0 3.7e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KNE01755.1 - 0.071 12.8 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 KNE01755.1 - 0.12 12.6 0.6 0.27 11.5 0.1 1.8 1 1 0 1 1 1 0 RWD domain DUF4246 PF14033.6 KNE01756.1 - 8.3e-127 424.0 0.1 9.8e-127 423.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) DUF1837 PF08878.11 KNE01756.1 - 0.024 14.4 0.1 0.053 13.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1837) Cry1Ac_D5 PF17997.1 KNE01756.1 - 0.093 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Insecticidal delta-endotoxin CryIA(c) domain 5 Methyltransf_11 PF08241.12 KNE01757.1 - 1.7e-16 60.6 0.0 6.7e-16 58.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNE01757.1 - 5.5e-16 59.1 0.0 1.5e-15 57.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNE01757.1 - 7.2e-16 58.5 0.1 1.4e-15 57.5 0.1 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNE01757.1 - 5.8e-15 55.4 0.2 8.8e-15 54.8 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNE01757.1 - 4.4e-14 53.0 0.0 3.8e-13 50.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KNE01757.1 - 2.3e-11 43.5 0.0 3.4e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KNE01757.1 - 1e-05 25.1 0.0 1.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KNE01757.1 - 0.03 13.7 0.0 0.11 11.8 0.0 1.7 1 1 1 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_33 PF10017.9 KNE01757.1 - 0.033 13.4 0.0 0.063 12.4 0.0 1.6 1 1 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent DUF1428 PF07237.11 KNE01757.1 - 0.048 13.9 0.0 0.097 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) FtsJ PF01728.19 KNE01757.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.12 KNE01757.1 - 0.075 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) CmcI PF04989.12 KNE01757.1 - 0.081 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase Flavodoxin_1 PF00258.25 KNE01757.1 - 0.16 12.2 0.2 0.84 9.8 0.2 2.1 1 1 0 1 1 1 0 Flavodoxin RST PF12174.8 KNE01757.1 - 0.22 11.4 0.5 11 6.0 0.1 2.3 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain Methyltransf_11 PF08241.12 KNE01759.1 - 7.4e-17 61.8 0.0 2.5e-16 60.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNE01759.1 - 2.3e-16 60.0 0.0 3.4e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNE01759.1 - 7.1e-16 58.7 0.0 1.5e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNE01759.1 - 3.3e-14 53.4 0.0 6.5e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNE01759.1 - 3e-12 46.7 0.0 3.9e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KNE01759.1 - 1.8e-09 37.3 0.0 3.1e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_33 PF10017.9 KNE01759.1 - 7.5e-05 22.0 0.0 0.00089 18.5 0.0 2.3 2 1 1 3 3 3 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_32 PF13679.6 KNE01759.1 - 0.00024 21.1 0.0 0.00066 19.7 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 KNE01759.1 - 0.0062 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KNE01759.1 - 0.0074 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 KNE01759.1 - 0.081 12.1 0.0 0.23 10.6 0.0 1.7 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family PCMT PF01135.19 KNE01759.1 - 0.18 11.5 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pkinase PF00069.25 KNE01761.1 - 2.4e-24 86.1 0.0 3.7e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE01761.1 - 8.3e-12 44.9 0.0 1.2e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNE01761.1 - 7.5e-08 31.5 0.0 1.2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KNE01761.1 - 0.0083 16.1 0.2 0.44 10.4 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family PIP49_C PF12260.8 KNE01761.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Pox_ser-thr_kin PF05445.11 KNE01761.1 - 0.22 10.5 0.0 0.32 9.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-AN1 PF01428.16 KNE01762.1 - 7.5e-10 38.8 11.0 1.2e-09 38.2 11.0 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger RNase_P_p30 PF01876.16 KNE01763.1 - 1.2e-60 204.7 0.0 1.4e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 Elongin_A PF06881.11 KNE01764.1 - 8.8e-26 90.5 0.0 1.7e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A CRAL_TRIO PF00650.20 KNE01765.1 - 8.4e-41 139.3 0.0 1.2e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KNE01765.1 - 3.7e-17 62.2 2.2 3.7e-17 62.2 2.2 1.9 2 1 0 2 2 2 1 CRAL/TRIO, N-terminal domain UBA_4 PF14555.6 KNE01765.1 - 0.17 11.7 0.1 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 UBA-like domain EXOSC1 PF10447.9 KNE01766.1 - 2.5e-36 124.6 0.4 6.4e-36 123.3 0.0 1.8 2 0 0 2 2 2 1 Exosome component EXOSC1/CSL4 DUF5549 PF17703.1 KNE01770.1 - 1.1 8.8 5.2 1.3 8.7 5.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5549) WWE PF02825.20 KNE01771.1 - 0.034 14.7 0.2 0.041 14.5 0.2 1.2 1 0 0 1 1 1 0 WWE domain ThiS-like PF14453.6 KNE01771.1 - 0.1 12.7 0.0 0.14 12.3 0.0 1.4 1 1 0 1 1 1 0 ThiS-like ubiquitin Globin PF00042.22 KNE01772.1 - 8.3e-06 26.3 0.0 2.4e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Globin Romo1 PF10247.9 KNE01777.1 - 0.081 13.3 0.2 0.34 11.3 0.0 1.8 1 1 1 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 ORC_WH_C PF18137.1 KNE01779.1 - 0.039 14.0 0.3 0.04 14.0 0.3 1.1 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DUF3915 PF13054.6 KNE01779.1 - 0.088 12.8 1.1 0.16 12.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) DUF3824 PF12868.7 KNE01779.1 - 0.13 12.9 6.5 0.11 13.1 5.6 1.3 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) Atrophin-1 PF03154.15 KNE01779.1 - 0.7 8.1 4.1 0.8 7.9 4.1 1.2 1 0 0 1 1 1 0 Atrophin-1 family bZIP_1 PF00170.21 KNE01780.1 - 8.4e-05 22.6 7.0 0.00019 21.5 7.0 1.6 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KNE01780.1 - 8.4e-05 22.6 8.6 0.00015 21.8 8.7 1.6 1 1 0 1 1 1 1 Basic region leucine zipper Tower PF09121.10 KNE01780.1 - 0.009 16.2 2.2 0.0091 16.2 0.1 1.9 2 1 0 2 2 2 1 Tower DUF883 PF05957.13 KNE01781.1 - 0.00091 19.8 9.6 0.0069 17.0 2.7 2.4 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) PIN_8 PF18476.1 KNE01781.1 - 0.0056 16.6 5.3 0.0071 16.2 5.3 1.1 1 0 0 1 1 1 1 PIN like domain Apolipoprotein PF01442.18 KNE01781.1 - 0.01 15.8 4.1 0.015 15.2 4.1 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF5353 PF17304.2 KNE01781.1 - 0.013 15.2 0.3 0.021 14.6 0.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5353) Prominin PF05478.11 KNE01781.1 - 0.026 12.5 1.8 0.03 12.3 1.8 1.1 1 0 0 1 1 1 0 Prominin KfrA_N PF11740.8 KNE01781.1 - 0.029 15.0 6.9 0.069 13.8 5.3 2.0 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Borrelia_P83 PF05262.11 KNE01781.1 - 0.079 11.4 13.0 0.09 11.3 13.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein TMPIT PF07851.13 KNE01781.1 - 0.079 12.2 1.2 0.095 11.9 1.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF3584 PF12128.8 KNE01781.1 - 0.12 9.9 5.8 0.14 9.6 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Mitofilin PF09731.9 KNE01781.1 - 0.12 11.2 13.1 0.14 11.0 13.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF913 PF06025.12 KNE01781.1 - 0.24 10.3 4.6 0.31 10.0 4.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Vma12 PF11712.8 KNE01781.1 - 0.28 11.3 3.8 0.64 10.1 3.8 1.6 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase GCN5L1 PF06320.13 KNE01781.1 - 0.29 11.3 7.9 0.41 10.8 7.9 1.3 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) TraF PF13728.6 KNE01781.1 - 0.46 10.3 8.1 0.65 9.8 8.1 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein ATP-synt_B PF00430.18 KNE01781.1 - 0.61 10.2 18.1 4.9 7.2 14.8 2.2 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) NARP1 PF12569.8 KNE01781.1 - 1.2 8.0 13.3 1.4 7.7 13.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 YtxH PF12732.7 KNE01781.1 - 1.5 9.4 18.8 9.2e+02 0.5 18.8 2.6 1 1 0 1 1 1 0 YtxH-like protein FGF-BP1 PF06473.12 KNE01781.1 - 1.6 8.5 8.4 2 8.2 8.4 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Vfa1 PF08432.10 KNE01781.1 - 1.7 8.9 13.6 2.3 8.5 13.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 V-ATPase_G_2 PF16999.5 KNE01781.1 - 3 8.3 13.4 4.1 7.9 12.0 1.9 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF4407 PF14362.6 KNE01781.1 - 4.7 6.5 9.0 8 5.7 9.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDPS PF16715.5 KNE01781.1 - 9.9 5.7 7.0 3 7.5 2.4 1.9 1 1 1 2 2 2 0 Cyclodipeptide synthase Ribosomal_S5 PF00333.20 KNE01782.1 - 1e-26 92.6 2.9 2.8e-26 91.3 2.4 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KNE01782.1 - 3.1e-23 81.0 0.0 5.2e-23 80.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain CoA_binding_3 PF13727.6 KNE01782.1 - 0.0093 16.0 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 CoA-binding domain zf-CCCH_2 PF14608.6 KNE01783.1 - 1.6e-09 37.9 51.4 0.00039 20.8 1.3 5.4 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 KNE01783.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Cpn60_TCP1 PF00118.24 KNE01784.1 - 1.1e-142 476.1 11.0 1.3e-142 475.9 11.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2264 PF10022.9 KNE01784.1 - 0.081 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) tRNA-synt_2 PF00152.20 KNE01785.1 - 2.4e-78 263.4 0.6 4.2e-78 262.6 0.6 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KNE01785.1 - 0.00018 21.4 0.2 0.00035 20.5 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ATP-synt_B PF00430.18 KNE01785.1 - 0.023 14.8 6.9 0.048 13.7 6.9 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) IR1-M PF12185.8 KNE01786.1 - 0.15 12.0 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain GSH_synth_ATP PF03917.17 KNE01789.1 - 1.2e-127 425.8 0.0 1.3e-127 425.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KNE01789.1 - 1.5e-33 115.3 0.0 3.2e-33 114.2 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic glutathione synthase mRNA_decap_C PF16741.5 KNE01789.1 - 0.012 14.9 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus SIL1 PF16782.5 KNE01792.1 - 1.9e-58 198.0 1.7 2.7e-58 197.5 1.7 1.2 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 DUF2102 PF09875.9 KNE01792.1 - 0.038 13.7 0.0 0.082 12.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) RICTOR_V PF14668.6 KNE01792.1 - 0.057 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 Z1 PF10593.9 KNE01792.1 - 0.17 11.3 1.0 1.7 8.1 0.1 2.2 2 0 0 2 2 2 0 Z1 domain JAB PF01398.21 KNE01792.1 - 0.19 11.7 1.1 0.56 10.2 0.0 2.3 2 1 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease YtxH PF12732.7 KNE01792.1 - 0.87 10.2 4.8 1 10.0 0.5 2.7 2 1 0 2 2 2 0 YtxH-like protein DUF2340 PF10209.9 KNE01793.1 - 3.8e-46 156.4 1.6 4.4e-46 156.2 1.6 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) CH PF00307.31 KNE01794.1 - 3e-17 62.8 5.6 2.4e-13 50.2 0.2 4.2 3 1 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KNE01794.1 - 0.0027 17.5 1.0 0.034 14.0 0.6 3.1 2 1 0 2 2 2 1 CAMSAP CH domain Elf4 PF07011.11 KNE01794.1 - 0.11 12.5 2.2 0.38 10.7 0.2 2.7 2 0 0 2 2 2 0 Early Flowering 4 domain Pkinase PF00069.25 KNE01795.1 - 2e-57 194.6 0.1 2.3e-57 194.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE01795.1 - 8.5e-17 61.3 0.0 1.6e-16 60.4 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KNE01795.1 - 8.6e-07 29.1 0.0 1.3e-05 25.3 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KNE01795.1 - 0.0026 17.4 0.2 0.0051 16.4 0.2 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KNE01795.1 - 0.034 12.9 0.0 0.057 12.2 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase Kinase-like PF14531.6 KNE01795.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Sld7_C PF18596.1 KNE01796.1 - 3.5e-17 62.3 0.0 6.2e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Sld7 C-terminal domain Sld7_N PF18636.1 KNE01796.1 - 1.3e-05 25.5 0.0 2.8e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial morphogenesis protein SLD7 N-terminal domain Ribosomal_L27A PF00828.19 KNE01797.1 - 1.5e-28 100.0 0.1 3.7e-28 98.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF3629 PF12302.8 KNE01797.1 - 0.0044 16.5 0.3 0.022 14.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3629) DUF4880 PF16220.5 KNE01799.1 - 1.9e-06 27.7 4.7 0.2 11.6 0.4 4.2 4 0 0 4 4 4 3 Domain of unknown function (DUF4880) Peptidase_M22 PF00814.25 KNE01799.1 - 0.11 12.2 0.1 18 4.9 0.0 2.5 3 0 0 3 3 3 0 Glycoprotease family P21-Arc PF04062.14 KNE01799.1 - 4.6 7.3 14.2 7.8 6.5 4.4 3.3 2 1 1 3 3 3 0 ARP2/3 complex ARPC3 (21 kDa) subunit SQHop_cyclase_C PF13243.6 KNE01800.1 - 1.5e-36 126.1 0.4 1.8e-35 122.6 0.2 2.3 2 1 1 3 3 3 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KNE01800.1 - 6.9e-36 123.8 0.1 1.8e-31 109.4 0.0 3.4 2 1 2 4 4 4 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KNE01800.1 - 2e-22 78.6 4.0 1.7e-07 30.8 0.2 4.4 4 1 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 KNE01800.1 - 0.014 14.4 0.2 0.11 11.5 0.1 2.2 2 0 0 2 2 2 0 A-macroglobulin TED domain Nrap_D5 PF17406.2 KNE01801.1 - 5.3e-52 175.8 0.2 1.1e-51 174.9 0.2 1.5 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 KNE01801.1 - 6e-51 172.2 0.5 1.2e-48 164.7 0.1 2.6 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap_D4 PF17405.2 KNE01801.1 - 4.6e-50 169.9 0.0 9.7e-50 168.9 0.0 1.5 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 KNE01801.1 - 1.9e-43 148.3 0.0 4.1e-43 147.2 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap PF03813.14 KNE01801.1 - 8.2e-39 133.1 3.7 8.2e-39 133.1 3.7 2.1 2 0 0 2 2 2 1 Nrap protein domain 1 Nrap_D6 PF17407.2 KNE01801.1 - 1.7e-22 80.0 0.0 4.5e-22 78.7 0.0 1.8 1 0 0 1 1 1 1 Nrap protein domain 6 DUF4611 PF15387.6 KNE01801.1 - 0.31 11.3 8.9 0.74 10.1 8.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF1746 PF08508.10 KNE01802.1 - 6.1e-30 103.9 4.3 9.7e-30 103.3 4.3 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) ApbE PF02424.15 KNE01803.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.0 1 0 0 1 1 1 0 ApbE family RNA_pol_A_bac PF01000.26 KNE01804.1 - 1.7e-29 102.4 0.0 3.1e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KNE01804.1 - 1.1e-20 72.8 0.0 1.6e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain EMP24_GP25L PF01105.24 KNE01806.1 - 3.3e-46 157.5 1.0 4.1e-46 157.2 1.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Syntaxin PF00804.25 KNE01806.1 - 0.052 13.2 0.2 0.07 12.8 0.2 1.1 1 0 0 1 1 1 0 Syntaxin DUF2569 PF10754.9 KNE01806.1 - 0.078 13.4 1.3 0.087 13.3 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) Bot1p PF12298.8 KNE01807.1 - 4.6e-18 66.0 0.0 5.6e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Bot1p PF12298.8 KNE01808.1 - 6.5e-20 72.0 0.1 8.2e-20 71.7 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Pkinase PF00069.25 KNE01809.1 - 3.2e-39 134.9 0.0 5.2e-35 121.1 0.0 3.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNE01809.1 - 5.1e-14 52.2 0.0 5.1e-11 42.4 0.0 3.1 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KNE01809.1 - 0.00014 21.9 0.0 0.00032 20.7 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KNE01809.1 - 0.13 11.5 0.0 5.4 6.2 0.0 2.3 1 1 0 1 1 1 0 Kinase-like Brix PF04427.18 KNE01812.1 - 1.8e-38 132.6 2.1 2.5e-38 132.1 2.1 1.2 1 0 0 1 1 1 1 Brix domain Nucleoporin_N PF08801.11 KNE01813.1 - 2.6e-52 178.0 0.0 3.6e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KNE01813.1 - 4.4e-44 151.2 23.3 2.8e-43 148.6 23.3 1.9 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal O-FucT PF10250.9 KNE01813.1 - 0.072 12.8 0.9 0.14 11.9 0.9 1.4 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase DASH_Dad2 PF08654.10 KNE01814.1 - 2.6e-23 82.3 3.7 5.3e-23 81.3 3.7 1.5 1 1 0 1 1 1 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.10 KNE01814.1 - 0.0021 17.8 1.4 0.0033 17.1 1.4 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 HATPase_c_5 PF14501.6 KNE01814.1 - 0.019 14.8 0.1 0.025 14.5 0.1 1.2 1 0 0 1 1 1 0 GHKL domain DUF4570 PF15134.6 KNE01815.1 - 0.01 15.9 1.5 0.02 14.9 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) ZapB PF06005.12 KNE01815.1 - 0.15 12.5 3.3 0.33 11.4 3.0 1.7 1 1 0 1 1 1 0 Cell division protein ZapB BST2 PF16716.5 KNE01815.1 - 0.21 12.2 3.2 0.52 10.9 3.2 1.6 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 Thymidylat_synt PF00303.19 KNE01816.1 - 3.8e-112 373.8 0.0 4.4e-112 373.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase HSP9_HSP12 PF04119.12 KNE01817.1 - 4.7e-23 81.3 6.7 5.3e-23 81.2 6.7 1.0 1 0 0 1 1 1 1 Heat shock protein 9/12 4HBT PF03061.22 KNE01818.1 - 1.4e-09 38.2 0.0 1.9e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Peptidase_C48 PF02902.19 KNE01819.1 - 1.1e-24 87.6 0.3 1.1e-24 87.6 0.3 2.7 3 0 0 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain Laminin_II PF06009.12 KNE01820.1 - 0.029 14.4 12.4 0.035 14.1 10.7 2.0 2 0 0 2 2 2 0 Laminin Domain II UPF0449 PF15136.6 KNE01820.1 - 0.042 14.3 8.3 0.14 12.7 8.3 2.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF724 PF05266.14 KNE01820.1 - 0.4 10.5 13.6 0.79 9.5 13.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) AAA_23 PF13476.6 KNE01820.1 - 0.4 11.1 10.9 0.81 10.2 10.9 1.5 1 0 0 1 1 1 0 AAA domain YnfE PF17452.2 KNE01820.1 - 0.69 10.2 5.6 1.6 9.1 5.6 1.6 1 0 0 1 1 1 0 Uncharacterized YnfE-like PRIMA1 PF16101.5 KNE01820.1 - 0.99 9.5 4.6 1.7 8.7 4.6 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 FapA PF03961.13 KNE01820.1 - 1.2 7.6 11.8 1.9 7.0 11.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF573 PF04504.14 KNE01820.1 - 1.9 9.2 9.9 30 5.4 9.5 2.6 1 1 1 2 2 2 0 Protein of unknown function, DUF573 RabGAP-TBC PF00566.18 KNE01820.1 - 4.1 7.0 14.5 0.025 14.2 2.2 2.3 2 0 0 2 2 2 0 Rab-GTPase-TBC domain Exonuc_VII_L PF02601.15 KNE01820.1 - 6.1 6.3 9.7 10 5.6 9.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 KNE01820.1 - 6.8 5.5 7.4 10 4.9 7.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.12 KNE01820.1 - 8 6.5 9.5 9.4 6.3 7.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FAD_binding_3 PF01494.19 KNE01821.1 - 1.8e-25 90.0 0.0 3e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KNE01821.1 - 2.3e-06 27.8 0.1 4.4e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KNE01821.1 - 2.6e-06 27.3 0.0 0.0061 16.2 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.10 KNE01821.1 - 6e-06 25.5 0.0 2.7e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.14 KNE01821.1 - 6.2e-06 25.6 0.5 0.0031 16.8 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KNE01821.1 - 0.00017 22.0 1.6 0.0028 18.2 0.1 2.6 2 1 1 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KNE01821.1 - 0.0035 16.3 0.0 1.4 7.7 0.0 2.6 2 1 1 3 3 3 2 Tryptophan halogenase ApbA PF02558.16 KNE01821.1 - 0.0051 16.5 0.2 0.009 15.7 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Glu_dehyd_C PF16912.5 KNE01821.1 - 0.074 12.5 0.0 0.93 8.9 0.0 2.2 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus 3HCDH_N PF02737.18 KNE01821.1 - 0.097 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KNE01821.1 - 0.1 11.6 0.1 0.18 10.9 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 KNE01821.1 - 0.13 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Tim44 PF04280.15 KNE01822.1 - 2.3e-38 131.6 0.7 4.6e-38 130.6 0.2 1.8 2 0 0 2 2 2 1 Tim44-like domain Senescence PF06911.12 KNE01822.1 - 0.01 16.2 0.5 0.021 15.1 0.5 1.6 1 0 0 1 1 1 0 Senescence-associated protein Phycobilisome PF00502.19 KNE01822.1 - 0.12 12.3 0.1 0.27 11.1 0.1 1.6 1 0 0 1 1 1 0 Phycobilisome protein ArfGap PF01412.18 KNE01823.1 - 5.7e-35 119.9 0.0 1.3e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Sugar_tr PF00083.24 KNE01826.1 - 4.3e-92 309.3 25.9 5.4e-92 309.0 25.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNE01826.1 - 6.3e-14 51.7 44.5 6.5e-11 41.8 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4293 PF14126.6 KNE01826.1 - 0.076 13.3 0.8 0.2 11.9 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) Mpv17_PMP22 PF04117.12 KNE01827.1 - 0.00046 20.4 1.3 0.0011 19.1 1.3 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family ADH_zinc_N PF00107.26 KNE01828.1 - 2.9e-12 46.7 0.0 4.9e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KNE01828.1 - 0.0018 19.3 0.0 0.011 16.8 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KNE01828.1 - 0.018 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Amidohydro_1 PF01979.20 KNE01831.1 - 1.1e-34 120.4 0.0 9.4e-18 64.6 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KNE01831.1 - 6.1e-11 42.5 0.0 4.9e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family MARCKS PF02063.17 KNE01831.1 - 0.084 12.8 0.7 0.14 12.2 0.7 1.3 1 0 0 1 1 1 0 MARCKS family PBP1_TM PF14812.6 KNE01831.1 - 8 6.9 5.9 3.4 8.1 3.1 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3128 PF11326.8 KNE01832.1 - 4.9e-24 84.5 0.3 8.3e-24 83.8 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Ras PF00071.22 KNE01833.1 - 4.2e-23 81.7 0.0 4.8e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Utp12 PF04003.12 KNE01835.1 - 1.5e-21 76.7 1.1 1.5e-21 76.7 1.1 2.1 2 0 0 2 2 2 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KNE01835.1 - 0.006 16.8 0.3 0.11 12.8 0.0 3.0 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain ECH_2 PF16113.5 KNE01835.1 - 0.11 12.0 0.5 0.2 11.1 0.5 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Glyco_transf_22 PF03901.17 KNE01836.1 - 8.5e-67 226.2 24.1 1.1e-66 225.9 24.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Tn7_TnsC_Int PF11426.8 KNE01836.1 - 0.071 13.3 0.6 0.25 11.6 0.6 1.9 1 0 0 1 1 1 0 Tn7 transposition regulator TnsC Phage_holin_3_6 PF07332.11 KNE01836.1 - 2.4 8.2 6.0 0.43 10.6 1.0 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III AAA PF00004.29 KNE01837.1 - 5e-46 156.4 0.1 1.4e-45 155.0 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KNE01837.1 - 8.7e-10 38.4 0.2 5.6e-09 35.8 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KNE01837.1 - 4.8e-09 36.6 0.0 8.8e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KNE01837.1 - 2.1e-08 34.2 0.1 7.8e-08 32.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KNE01837.1 - 2.3e-08 34.6 0.1 3.2e-05 24.4 0.0 3.2 1 1 2 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KNE01837.1 - 2.8e-05 24.4 1.1 0.0064 16.8 0.0 2.6 1 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 KNE01837.1 - 4.9e-05 22.6 0.0 8.3e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KNE01837.1 - 0.00029 20.6 0.0 0.00083 19.1 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KNE01837.1 - 0.00031 20.8 0.0 0.00076 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_lid_3 PF17862.1 KNE01837.1 - 0.00037 20.3 0.0 0.00088 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain NTPase_1 PF03266.15 KNE01837.1 - 0.00069 19.6 0.0 0.0033 17.4 0.0 2.0 2 0 0 2 2 2 1 NTPase AAA_18 PF13238.6 KNE01837.1 - 0.00073 20.1 0.0 0.0031 18.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KNE01837.1 - 0.0014 18.2 0.1 0.0099 15.4 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_3 PF07726.11 KNE01837.1 - 0.002 18.0 0.0 0.01 15.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KNE01837.1 - 0.0022 18.2 0.0 0.0052 16.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain BCNT PF07572.12 KNE01837.1 - 0.0027 17.7 0.4 0.0054 16.8 0.4 1.5 1 0 0 1 1 1 1 Bucentaur or craniofacial development AAA_30 PF13604.6 KNE01837.1 - 0.0028 17.4 0.2 0.017 14.8 0.0 2.5 2 1 1 3 3 3 1 AAA domain TsaE PF02367.17 KNE01837.1 - 0.0042 17.1 0.0 0.0077 16.2 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KNE01837.1 - 0.005 17.2 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase TniB PF05621.11 KNE01837.1 - 0.0077 15.7 0.0 0.52 9.7 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 KNE01837.1 - 0.0078 15.6 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KNE01837.1 - 0.0079 15.4 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain NACHT PF05729.12 KNE01837.1 - 0.0093 15.9 0.2 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 KNE01837.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KNE01837.1 - 0.016 15.6 0.0 0.39 11.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KNE01837.1 - 0.016 15.5 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KNE01837.1 - 0.019 14.7 0.1 0.28 10.9 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KNE01837.1 - 0.025 14.3 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AFG1_ATPase PF03969.16 KNE01837.1 - 0.051 12.5 0.0 0.17 10.7 0.0 1.8 2 0 0 2 2 2 0 AFG1-like ATPase ATPase PF06745.13 KNE01837.1 - 0.055 12.8 0.2 0.87 8.9 0.0 2.2 2 0 0 2 2 2 0 KaiC ATPase_2 PF01637.18 KNE01837.1 - 0.055 13.4 0.8 0.49 10.3 0.0 2.5 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 KNE01837.1 - 0.065 13.0 0.1 0.11 12.2 0.0 1.6 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 KNE01837.1 - 0.071 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Bac_DnaA PF00308.18 KNE01837.1 - 0.089 12.6 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein ABC_tran PF00005.27 KNE01837.1 - 0.16 12.5 0.0 0.42 11.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 KNE01837.1 - 0.16 12.4 0.4 2.5 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KNE01837.1 - 0.21 11.1 2.5 0.25 10.9 0.1 2.1 2 1 0 3 3 2 0 AAA domain Parvo_NS1 PF01057.17 KNE01837.1 - 0.22 10.6 0.0 0.38 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Fmp27_WPPW PF10359.9 KNE01838.1 - 9.7e-114 380.9 7.2 9.7e-114 380.9 7.2 2.5 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.9 KNE01838.1 - 9.8e-102 341.3 18.0 1.9e-101 340.3 16.4 2.3 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27 PF10344.9 KNE01838.1 - 4.5e-70 236.8 31.9 4.5e-70 236.8 31.9 2.6 2 1 0 2 2 2 1 Mitochondrial protein from FMP27 Fmp27_GFWDK PF10347.9 KNE01838.1 - 1.3e-51 174.8 0.2 3.7e-51 173.3 0.1 1.9 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KNE01838.1 - 5.6e-39 133.5 2.0 1.4e-38 132.2 0.5 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 KNE01838.1 - 3.5e-18 66.2 0.0 3.5e-18 66.2 0.0 4.0 5 0 0 5 5 5 1 RNA pol II promoter Fmp27 protein domain DUF3618 PF12277.8 KNE01838.1 - 0.22 11.8 2.6 0.6 10.4 2.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) RabGAP-TBC PF00566.18 KNE01840.1 - 6.6e-51 173.0 0.2 1.7e-50 171.7 0.2 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 KNE01840.1 - 2.5e-09 37.0 0.5 8.9e-09 35.2 0.1 2.2 2 0 0 2 2 2 1 GRAM domain Vps36_ESCRT-II PF11605.8 KNE01840.1 - 0.0094 16.1 0.0 0.039 14.1 0.0 2.0 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 ANAPC8 PF04049.13 KNE01840.1 - 0.045 13.8 1.3 0.13 12.3 0.0 2.4 3 0 0 3 3 3 0 Anaphase promoting complex subunit 8 / Cdc23 Ribosomal_60s PF00428.19 KNE01840.1 - 1 10.0 5.7 0.33 11.6 0.2 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein TMEM247 PF15444.6 KNE01841.1 - 0.22 11.5 4.7 0.66 10.0 4.7 1.8 1 0 0 1 1 1 0 Transmembrane protein 247 DUF1770 PF08589.10 KNE01842.1 - 0.00012 23.0 1.1 0.00015 22.7 0.4 1.5 1 1 1 2 2 2 1 Fungal protein of unknown function (DUF1770) RNA_pol_A_bac PF01000.26 KNE01843.1 - 1e-29 103.2 0.0 1.6e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KNE01843.1 - 1.2e-17 63.0 0.0 1.6e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain His_biosynth PF00977.21 KNE01844.1 - 1.3e-27 96.8 0.0 1.9e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein DUF4602 PF15375.6 KNE01845.1 - 0.00072 19.9 0.5 0.00072 19.9 0.5 3.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4602) CDC45 PF02724.14 KNE01845.1 - 6.4 4.9 16.1 8.2 4.6 16.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Cnd2 PF05786.14 KNE01847.1 - 3.7e-148 495.5 26.2 8.3e-147 491.0 26.2 1.9 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KNE01847.1 - 0.001 19.3 0.0 0.001 19.3 0.0 3.2 4 0 0 4 4 4 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal DUF4724 PF15852.5 KNE01847.1 - 0.14 12.6 1.1 0.52 10.8 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4724) MCR_alpha PF02249.17 KNE01847.1 - 0.52 10.8 2.1 0.48 10.9 0.6 1.7 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain ADH_zinc_N_2 PF13602.6 KNE01848.1 - 1.2e-16 61.9 0.0 6.4e-16 59.6 0.0 2.2 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KNE01848.1 - 1.3e-09 38.1 0.0 4.3e-09 36.5 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KNE01848.1 - 0.0046 16.8 0.0 0.012 15.5 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PALB2_WD40 PF16756.5 KNE01848.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain Peptidase_M41 PF01434.18 KNE01849.1 - 1.6e-61 207.5 0.0 2.6e-61 206.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KNE01849.1 - 1.5e-41 141.9 0.0 6.9e-41 139.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KNE01849.1 - 5.3e-08 32.5 0.0 1.4e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KNE01849.1 - 9.4e-06 26.1 0.2 5.5e-05 23.6 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KNE01849.1 - 9.3e-05 21.8 0.0 0.0002 20.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KNE01849.1 - 0.00074 19.8 1.4 0.096 13.0 0.1 3.2 3 1 0 4 4 2 1 AAA domain AAA_5 PF07728.14 KNE01849.1 - 0.0017 18.3 0.1 0.0068 16.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KNE01849.1 - 0.0048 16.7 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KNE01849.1 - 0.015 15.4 0.0 0.049 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KNE01849.1 - 0.024 14.3 0.0 0.058 13.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 KNE01849.1 - 0.033 13.7 1.3 1.5 8.3 0.6 2.6 1 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KNE01849.1 - 0.041 13.3 0.3 0.084 12.2 0.3 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KNE01849.1 - 0.046 13.7 0.2 0.54 10.3 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KNE01849.1 - 0.098 12.8 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KNE01849.1 - 0.13 11.6 0.1 0.49 9.7 0.1 1.9 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.6 KNE01849.1 - 0.13 12.2 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KNE01849.1 - 0.14 12.8 0.0 0.34 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Cut12 PF11500.8 KNE01849.1 - 0.14 12.1 0.5 0.25 11.3 0.5 1.4 1 0 0 1 1 1 0 Spindle pole body formation-associated protein PhoH PF02562.16 KNE01849.1 - 0.18 11.2 0.3 0.46 9.9 0.2 1.6 2 0 0 2 2 2 0 PhoH-like protein RRM_1 PF00076.22 KNE01850.1 - 1.1e-06 28.4 0.0 2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 KNE01850.1 - 0.00048 20.9 0.0 0.0013 19.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_7 PF16367.5 KNE01850.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif MRP-L46 PF11788.8 KNE01851.1 - 2.2e-40 138.1 0.2 3.5e-40 137.5 0.2 1.3 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 COPIIcoated_ERV PF07970.12 KNE01852.1 - 1.2e-69 234.5 0.1 1.5e-69 234.2 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KNE01852.1 - 1.7e-26 92.4 0.4 5e-26 90.9 0.2 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) WD40 PF00400.32 KNE01853.1 - 6.4e-16 58.5 0.9 0.00081 20.2 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNE01853.1 - 3.4e-09 36.9 0.1 0.28 11.5 0.0 4.5 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KNE01853.1 - 8.7e-07 28.6 1.8 2.9e-06 26.8 1.8 1.7 1 1 0 1 1 1 1 WD40-like domain eIF2A PF08662.11 KNE01853.1 - 8.9e-06 25.7 0.1 2.8e-05 24.1 0.0 1.8 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A CNH PF00780.22 KNE01853.1 - 0.12 11.9 0.0 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 CNH domain Cytochrom_D1 PF02239.16 KNE01853.1 - 0.13 10.8 0.0 0.32 9.5 0.0 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain Adaptin_N PF01602.20 KNE01854.1 - 6.9e-90 302.1 14.5 1.4e-89 301.1 14.5 1.5 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KNE01854.1 - 7e-12 45.7 1.5 7e-12 45.7 1.5 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 MIF4G PF02854.19 KNE01854.1 - 0.017 14.8 0.1 0.017 14.8 0.1 3.5 4 0 0 4 4 4 0 MIF4G domain HEAT_2 PF13646.6 KNE01854.1 - 0.081 13.3 0.0 0.85 10.1 0.0 2.8 3 0 0 3 3 3 0 HEAT repeats HEAT PF02985.22 KNE01854.1 - 0.17 12.2 0.0 14 6.2 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat RR_TM4-6 PF06459.12 KNE01854.1 - 4.7 6.9 30.1 0.42 10.4 21.2 2.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 KxDL PF10241.9 KNE01855.1 - 8.3e-13 48.4 1.3 1.7e-12 47.5 1.3 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein Occludin_ELL PF07303.13 KNE01855.1 - 0.0014 19.3 2.9 0.0029 18.3 2.9 1.6 1 1 0 1 1 1 1 Occludin homology domain Metallopep PF12044.8 KNE01856.1 - 3.2e-151 503.8 0.0 3.9e-151 503.5 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_3 PF13582.6 KNE01856.1 - 0.00081 19.9 0.1 0.0017 18.9 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KNE01856.1 - 0.0031 17.7 0.2 0.0061 16.7 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 KNE01856.1 - 0.01 14.8 0.3 0.022 13.7 0.3 1.5 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_2 PF13574.6 KNE01856.1 - 0.031 14.2 0.1 0.068 13.1 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Jacalin PF01419.17 KNE01856.1 - 0.044 13.7 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 Jacalin-like lectin domain Peptidase_M10 PF00413.24 KNE01856.1 - 0.073 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Matrixin Reprolysin_4 PF13583.6 KNE01856.1 - 0.1 12.3 0.0 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 KNE01856.1 - 0.15 12.0 0.2 0.29 11.1 0.2 1.4 1 0 0 1 1 1 0 Peptidase family M54 Tyr-DNA_phospho PF06087.12 KNE01857.1 - 1.2e-103 347.3 0.0 1.7e-103 346.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 KNE01857.1 - 0.00013 21.9 0.3 0.0019 18.1 0.1 2.3 2 0 0 2 2 2 1 PLD-like domain SMC_N PF02463.19 KNE01858.1 - 1.3e-57 194.8 40.2 7e-57 192.4 40.2 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KNE01858.1 - 8.4e-25 87.4 0.0 2.5e-24 85.8 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KNE01858.1 - 3.3e-17 63.2 6.0 1.1e-08 35.3 0.3 3.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KNE01858.1 - 1.9e-16 60.8 71.4 1.1e-12 48.4 20.9 4.8 2 2 1 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 KNE01858.1 - 2.9e-10 41.0 20.0 2.9e-10 41.0 20.0 7.3 2 2 2 4 4 4 1 AAA domain BRCT PF00533.26 KNE01858.1 - 0.0014 19.0 0.2 1.6 9.2 0.0 3.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Tropomyosin_1 PF12718.7 KNE01858.1 - 0.0015 18.7 15.2 0.0015 18.7 15.2 7.3 3 3 2 6 6 6 1 Tropomyosin like AAA_29 PF13555.6 KNE01858.1 - 0.014 15.1 0.0 0.039 13.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KNE01858.1 - 1.6 9.3 0.0 1.6 9.3 0.0 6.1 4 3 0 4 4 4 0 ABC transporter TetR PF13972.6 KNE01858.1 - 3.3 7.4 11.5 2 8.1 0.2 4.5 4 0 0 4 4 4 0 Bacterial transcriptional repressor FA_desaturase PF00487.24 KNE01859.1 - 2e-30 106.5 28.9 2.8e-30 106.0 28.9 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KNE01859.1 - 2.5e-09 37.2 0.0 6.2e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NUFIP1 PF10453.9 KNE01860.1 - 1.6e-19 69.5 3.4 3.8e-19 68.3 3.4 1.6 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH_4 PF18044.1 KNE01860.1 - 5.9e-05 22.8 5.6 9.2e-05 22.2 5.6 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KNE01860.1 - 0.00013 21.8 3.1 0.00018 21.3 3.1 1.2 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KNE01860.1 - 0.00041 21.0 0.7 0.00075 20.2 0.7 1.4 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 KNE01860.1 - 0.00088 19.2 8.4 0.0014 18.6 8.4 1.3 1 0 0 1 1 1 1 Zinc finger domain PEHE PF15275.6 KNE01860.1 - 0.028 15.0 3.7 0.057 14.1 3.7 1.5 1 0 0 1 1 1 0 PEHE domain ANAPC_CDC26 PF10471.9 KNE01860.1 - 0.27 12.1 4.2 0.85 10.5 4.2 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 tRNA-synt_2b PF00587.25 KNE01863.1 - 2.1e-34 119.0 0.0 3.6e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KNE01863.1 - 9.6e-24 83.7 8.1 9.6e-24 83.7 8.1 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain GED PF02212.18 KNE01863.1 - 0.066 13.4 3.3 0.17 12.0 3.3 1.6 1 0 0 1 1 1 0 Dynamin GTPase effector domain NPV_P10 PF05531.12 KNE01863.1 - 0.068 13.6 3.1 0.096 13.2 1.6 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein WD40 PF00400.32 KNE01864.1 - 5.3e-20 71.4 8.3 0.0024 18.6 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNE01864.1 - 6e-07 29.7 0.1 4 7.8 0.0 5.1 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KNE01864.1 - 0.0099 14.6 1.6 0.1 11.3 0.2 2.8 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Cytokin_check_N PF10407.9 KNE01865.1 - 6.7e-28 96.4 0.1 1.5e-27 95.3 0.1 1.6 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus Ribonuclease_3 PF00636.26 KNE01866.1 - 3e-05 24.6 0.1 8.8e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Ribonuclease III domain YliH PF10799.8 KNE01866.1 - 0.0032 17.4 0.0 0.0074 16.2 0.0 1.6 1 0 0 1 1 1 1 Biofilm formation protein (YliH/bssR) DAO PF01266.24 KNE01868.1 - 1.7e-26 93.7 0.0 2e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KNE01868.1 - 0.0079 15.5 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KNE01868.1 - 0.0092 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KNE01868.1 - 0.011 14.8 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein SF3A3 PF16837.5 KNE01868.1 - 0.038 14.5 0.3 0.084 13.4 0.3 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 DUF2956 PF11169.8 KNE01868.1 - 0.22 11.7 0.0 0.35 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Amidase PF01425.21 KNE01869.1 - 8.4e-92 308.5 0.0 1.2e-91 308.0 0.0 1.2 1 0 0 1 1 1 1 Amidase Ferric_reduct PF01794.19 KNE01875.1 - 1.3e-20 73.8 13.6 3.8e-20 72.3 13.6 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KNE01875.1 - 9e-19 68.1 0.0 1.4e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KNE01875.1 - 1.7e-18 66.7 0.0 3.3e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain HhH-GPD PF00730.25 KNE01876.1 - 3.4e-10 40.3 0.0 6.8e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KNE01876.1 - 0.14 12.1 0.0 0.98 9.4 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif Antifungal_pept PF11410.8 KNE01879.1 - 0.0053 16.6 0.0 0.0087 15.9 0.0 1.3 1 0 0 1 1 1 1 Antifungal peptide Transthyretin PF00576.21 KNE01882.1 - 1.1e-33 116.1 0.0 1.4e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family Stn1 PF10451.9 KNE01883.1 - 1.6e-13 50.2 0.0 2.5e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 KNE01883.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Methyltransf_8 PF05148.15 KNE01884.1 - 9.3e-62 208.7 6.0 1.2e-29 103.7 0.0 3.5 2 1 1 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KNE01884.1 - 5.5e-07 30.1 0.0 3.2e-06 27.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNE01884.1 - 0.00014 22.5 0.0 0.0098 16.6 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNE01884.1 - 0.0045 16.8 0.1 0.15 11.8 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Peptidase_C11 PF03415.14 KNE01884.1 - 0.031 13.7 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Clostripain family MTS PF05175.14 KNE01884.1 - 0.082 12.4 0.0 8.2 6.0 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase small domain WD40 PF00400.32 KNE01885.1 - 4.5e-08 33.6 13.0 0.0044 17.8 0.6 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNE01885.1 - 4.9e-08 33.2 0.4 2e-05 24.8 0.0 3.7 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain HECT PF00632.25 KNE01886.1 - 9.5e-96 320.9 0.1 1.3e-95 320.5 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KNE01886.1 - 1.6e-33 114.4 24.4 1.2e-11 44.5 2.8 3.9 4 0 0 4 4 4 3 WW domain C2 PF00168.30 KNE01886.1 - 5.1e-18 65.3 0.1 1.4e-17 63.9 0.1 1.8 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.25 KNE01888.1 - 4e-23 82.1 0.0 6.6e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE01888.1 - 3.4e-10 39.7 0.0 4.9e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNE01888.1 - 1.5e-08 33.9 0.5 2.4e-08 33.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KNE01888.1 - 0.0017 18.3 0.0 0.18 11.7 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family AgrB PF04647.15 KNE01890.1 - 0.23 10.8 0.4 0.21 10.9 0.4 1.0 1 0 0 1 1 1 0 Accessory gene regulator B MRG PF05712.13 KNE01891.1 - 2e-37 128.4 0.7 3.8e-37 127.5 0.7 1.4 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KNE01891.1 - 9.8e-08 31.8 0.0 2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain RGI1 PF10843.8 KNE01892.1 - 4.5e-104 346.2 5.0 5.2e-104 346.0 5.0 1.0 1 0 0 1 1 1 1 Respiratory growth induced protein 1 Tim17 PF02466.19 KNE01894.1 - 4.7e-37 126.8 6.2 5.7e-37 126.5 6.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Med4 PF10018.9 KNE01895.1 - 0.0027 17.4 2.2 0.004 16.9 2.2 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 YojJ PF10372.9 KNE01895.1 - 0.086 12.9 1.9 0.2 11.8 1.9 1.6 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus HSCB_C PF07743.13 KNE01895.1 - 0.21 12.1 3.3 0.37 11.3 3.3 1.4 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain DUF4404 PF14357.6 KNE01895.1 - 0.37 11.5 5.0 0.8 10.4 5.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Chitin_synth_1 PF01644.17 KNE01896.1 - 2.6e-70 235.6 0.8 6.5e-70 234.3 0.1 1.9 2 0 0 2 2 2 1 Chitin synthase Chitin_synth_2 PF03142.15 KNE01896.1 - 6.9e-23 81.1 4.8 1.2e-16 60.4 0.0 3.1 2 1 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 KNE01896.1 - 1.2e-22 79.6 0.0 3.9e-22 78.0 0.0 1.9 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 KNE01896.1 - 3.6e-09 36.8 0.9 1.2e-08 35.1 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KNE01896.1 - 0.015 15.1 0.0 3.8 7.3 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 A_deaminase PF00962.22 KNE01897.1 - 6.9e-82 275.4 0.0 7.9e-82 275.2 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase IGR PF09597.10 KNE01898.1 - 0.0021 18.1 0.4 0.0041 17.2 0.4 1.5 1 0 0 1 1 1 1 IGR protein motif DUF769 PF05590.11 KNE01898.1 - 0.0042 16.6 0.1 0.005 16.3 0.1 1.1 1 0 0 1 1 1 1 Xylella fastidiosa protein of unknown function (DUF769) Inhibitor_I9 PF05922.16 KNE01898.1 - 0.014 16.1 0.8 0.028 15.1 0.6 1.6 1 1 0 1 1 1 0 Peptidase inhibitor I9 CSRNP_N PF16019.5 KNE01898.1 - 0.038 13.9 0.9 0.045 13.7 0.9 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus ABC2_membrane_3 PF12698.7 KNE01898.1 - 0.038 13.1 0.6 0.042 13.0 0.6 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein EPO_TPO PF00758.18 KNE01898.1 - 0.077 13.0 0.2 0.1 12.6 0.2 1.2 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin SSF PF00474.17 KNE01898.1 - 0.088 11.7 0.1 0.1 11.4 0.1 1.1 1 0 0 1 1 1 0 Sodium:solute symporter family LprI PF07007.12 KNE01898.1 - 0.093 13.4 0.1 0.14 12.8 0.1 1.2 1 0 0 1 1 1 0 Lysozyme inhibitor LprI Atg8 PF02991.16 KNE01899.1 - 3.3e-47 158.9 0.1 3.9e-47 158.7 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KNE01899.1 - 7.6e-06 26.3 0.0 9.7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Holin_BhlA PF10960.8 KNE01899.1 - 0.1 12.6 1.0 0.43 10.6 0.5 2.0 2 0 0 2 2 2 0 BhlA holin family GatB_N PF02934.15 KNE01900.1 - 2e-92 309.5 0.0 2.5e-92 309.1 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KNE01900.1 - 2.1e-24 86.1 0.1 4e-24 85.2 0.1 1.5 1 0 0 1 1 1 1 GatB domain STE3 PF02076.15 KNE01901.1 - 8.4e-74 248.4 20.9 9.8e-74 248.1 20.9 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF2070 PF09843.9 KNE01901.1 - 0.27 9.5 10.1 0.38 9.0 10.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) IBN_N PF03810.19 KNE01903.1 - 7.9e-13 48.1 6.2 6.8e-11 41.9 0.7 4.1 3 0 0 3 3 3 2 Importin-beta N-terminal domain HEAT_EZ PF13513.6 KNE01903.1 - 5.9e-12 45.8 15.4 5.6e-08 33.1 0.3 8.0 9 0 0 9 9 9 2 HEAT-like repeat HEAT_2 PF13646.6 KNE01903.1 - 5.5e-10 39.5 1.1 0.0061 16.9 0.0 6.3 3 2 2 6 6 6 3 HEAT repeats RIX1 PF08167.12 KNE01903.1 - 8.9e-09 35.3 0.3 0.012 15.3 0.0 5.8 6 1 0 6 6 6 2 rRNA processing/ribosome biogenesis HEAT PF02985.22 KNE01903.1 - 1.9e-07 30.7 15.8 0.0098 16.1 0.1 9.2 12 0 0 12 12 10 2 HEAT repeat IFRD PF05004.13 KNE01903.1 - 3.3e-07 29.7 4.0 0.0013 17.9 0.4 5.4 4 1 2 6 6 6 3 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 KNE01903.1 - 2.7e-05 24.3 6.0 0.014 15.4 0.1 4.9 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 KNE01903.1 - 4.9e-05 23.3 9.6 0.077 12.9 0.0 6.2 5 2 2 7 7 7 1 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 KNE01903.1 - 9.7e-05 22.9 7.6 1.5 9.5 0.0 6.5 6 1 1 7 7 7 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KNE01903.1 - 0.0019 17.8 0.4 5.6 6.5 0.0 4.0 3 0 0 3 3 3 2 CLASP N terminal TIP120 PF08623.10 KNE01903.1 - 0.0047 16.7 9.3 1.3 8.8 0.0 5.1 4 1 1 5 5 5 1 TATA-binding protein interacting (TIP20) Ipi1_N PF12333.8 KNE01903.1 - 0.024 15.2 0.0 17 6.1 0.0 4.6 4 1 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation DEAD PF00270.29 KNE01904.1 - 7.9e-43 146.3 2.7 1.2e-42 145.6 2.7 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNE01904.1 - 5.6e-31 107.2 0.1 4.8e-30 104.2 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KNE01904.1 - 6.4e-05 22.7 1.3 0.00022 21.0 0.6 2.0 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KNE01904.1 - 0.00035 20.6 0.1 0.00074 19.6 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KNE01904.1 - 0.00043 20.6 0.6 0.00085 19.7 0.6 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KNE01904.1 - 0.0078 16.5 0.7 0.029 14.6 0.7 1.9 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 KNE01904.1 - 0.052 13.5 0.3 0.28 11.1 0.2 2.4 1 1 0 1 1 1 0 Flavivirus DEAD domain DUF4767 PF15983.5 KNE01904.1 - 0.072 13.4 0.0 0.69 10.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4767) PRK PF00485.18 KNE01905.1 - 1.1e-16 61.2 0.4 1.7e-14 54.0 0.2 2.1 1 1 1 2 2 2 2 Phosphoribulokinase / Uridine kinase family CoaE PF01121.20 KNE01905.1 - 0.026 14.2 0.1 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase FMN_red PF03358.15 KNE01905.1 - 0.087 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 NADPH-dependent FMN reductase Nucleoporin_N PF08801.11 KNE01906.1 - 9.7e-117 390.3 9.8 1.5e-116 389.7 9.8 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KNE01906.1 - 3.3e-103 346.5 1.3 2.2e-102 343.8 1.3 2.0 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Peptidase_M28 PF04389.17 KNE01908.1 - 1.4e-23 83.7 0.0 1.9e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KNE01908.1 - 0.0012 18.6 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 SSB PF00436.25 KNE01909.1 - 2.2e-15 56.6 0.1 2.7e-15 56.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family AAA_34 PF13872.6 KNE01909.1 - 0.079 11.8 0.0 0.084 11.7 0.0 1.1 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 DUF3844 PF12955.7 KNE01913.1 - 7.5e-29 100.0 5.3 1.3e-28 99.2 5.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Bul1_C PF04426.12 KNE01913.1 - 0.042 13.2 1.2 0.071 12.5 0.4 1.6 1 1 0 1 1 1 0 Bul1 C terminus EGF_CA PF07645.15 KNE01913.1 - 0.4 10.9 10.1 0.74 10.1 10.1 1.4 1 0 0 1 1 1 0 Calcium-binding EGF domain Evr1_Alr PF04777.13 KNE01914.1 - 2.9e-26 91.8 0.1 4.8e-26 91.1 0.1 1.4 1 0 0 1 1 1 1 Erv1 / Alr family APOBEC1 PF18769.1 KNE01914.1 - 0.095 13.0 0.0 0.2 11.9 0.0 1.6 1 1 0 1 1 1 0 APOBEC1 G-gamma PF00631.22 KNE01915.1 - 2.3e-15 56.3 0.0 2.6e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 GGL domain STELLO PF03385.17 KNE01915.1 - 0.16 10.7 0.0 0.19 10.5 0.0 1.0 1 0 0 1 1 1 0 STELLO glycosyltransferases V-SNARE_C PF12352.8 KNE01916.1 - 3.8e-14 52.7 0.6 3.8e-14 52.7 0.6 3.2 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus DUF5344 PF17279.2 KNE01916.1 - 0.0013 19.3 1.2 0.003 18.1 1.1 1.7 1 1 0 1 1 1 1 Family of unknown function (DUF5344) Cas_TM1802 PF09484.10 KNE01916.1 - 0.0077 15.0 0.5 0.0079 15.0 0.5 1.2 1 0 0 1 1 1 1 CRISPR-associated protein TM1802 (cas_TM1802) Laminin_I PF06008.14 KNE01916.1 - 0.14 11.8 9.4 0.23 11.1 6.3 2.4 2 1 1 3 3 3 0 Laminin Domain I Sec20 PF03908.13 KNE01916.1 - 0.27 11.2 6.4 9 6.3 0.0 3.1 2 1 1 3 3 3 0 Sec20 JHY PF15261.6 KNE01916.1 - 0.32 11.7 0.1 0.32 11.7 0.1 2.5 2 1 0 2 2 2 0 Jhy protein PMC2NT PF08066.12 KNE01916.1 - 0.79 10.4 3.7 1.6 9.5 0.6 2.4 2 1 0 2 2 2 0 PMC2NT (NUC016) domain V_ATPase_I PF01496.19 KNE01916.1 - 0.88 7.4 4.3 0.95 7.3 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.20 KNE01916.1 - 1.2 9.1 6.5 0.17 11.8 2.4 1.6 2 0 0 2 2 2 0 Prefoldin subunit Syntaxin-6_N PF09177.11 KNE01916.1 - 1.4 9.5 6.5 2.5 8.7 3.4 2.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal UPF0184 PF03670.13 KNE01916.1 - 5.4 7.5 6.8 1.4 9.4 0.6 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) AAA_17 PF13207.6 KNE01917.1 - 0.12 12.8 0.0 0.96 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF1691 PF07950.11 KNE01918.1 - 4.8e-21 75.5 2.0 1.1e-11 45.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) DUF3341 PF11821.8 KNE01918.1 - 0.17 11.5 2.3 3.7 7.2 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3341) MWFE PF15879.5 KNE01918.1 - 0.18 12.0 3.0 2.8 8.2 0.2 2.9 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit Sdh_cyt PF01127.22 KNE01918.1 - 1.3 9.1 10.7 2.3 8.3 4.9 2.7 2 2 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit NifU_N PF01592.16 KNE01919.1 - 7.3e-59 197.5 0.3 8.8e-59 197.3 0.3 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 KNE01919.1 - 0.0066 16.7 0.1 0.011 15.9 0.1 1.3 1 0 0 1 1 1 1 TSCPD domain CDK2AP PF09806.9 KNE01921.1 - 0.19 11.7 0.0 0.19 11.7 0.0 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein REC114-like PF15165.6 KNE01921.1 - 0.71 9.6 3.5 0.58 9.9 0.2 2.2 2 0 0 2 2 2 0 Meiotic recombination protein REC114-like Ribosomal_L5e PF17144.4 KNE01922.1 - 8.4e-82 273.0 0.7 1.4e-81 272.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KNE01922.1 - 6.7e-32 110.3 12.9 6.7e-32 110.3 12.9 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.6 KNE01922.1 - 0.0027 17.9 1.9 0.43 10.8 0.0 3.1 2 1 1 3 3 3 1 Threonine synthase N terminus DUF1160 PF06648.11 KNE01922.1 - 0.0068 16.4 0.1 0.015 15.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1160) Ribosomal_L18p PF00861.22 KNE01922.1 - 0.018 15.4 2.2 0.022 15.1 0.0 2.0 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast NAC PF01849.18 KNE01922.1 - 0.039 13.9 0.0 0.089 12.8 0.0 1.5 1 0 0 1 1 1 0 NAC domain Colicin_immun PF09204.10 KNE01922.1 - 0.075 13.6 2.4 0.24 11.9 1.1 2.5 2 1 0 2 2 2 0 Bacterial self-protective colicin-like immunity NAD_binding_5 PF07994.12 KNE01922.1 - 3.7 6.8 5.0 46 3.2 5.0 2.0 1 1 0 1 1 1 0 Myo-inositol-1-phosphate synthase MTP18 PF10558.9 KNE01923.1 - 4.7e-71 238.2 0.0 5.6e-71 238.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) 3-HAO PF06052.12 KNE01924.1 - 1.1e-67 226.4 0.1 1.2e-67 226.2 0.1 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KNE01924.1 - 1.7e-06 27.6 0.0 2.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain DZR PF12773.7 KNE01924.1 - 0.0028 17.6 0.2 0.0084 16.1 0.2 1.8 1 1 0 1 1 1 1 Double zinc ribbon Cupin_1 PF00190.22 KNE01924.1 - 0.027 14.1 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Cupin C1_1 PF00130.22 KNE01924.1 - 0.048 13.5 1.4 0.37 10.7 0.1 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.10 KNE01924.1 - 0.33 11.1 3.4 2.6 8.2 3.4 2.1 1 1 0 1 1 1 0 Zinc ribbon domain ADK_lid PF05191.14 KNE01924.1 - 0.62 10.1 6.9 7.5 6.6 0.5 2.8 3 0 0 3 3 3 0 Adenylate kinase, active site lid DUF2407_C PF13373.6 KNE01925.1 - 1.2e-36 126.0 0.1 2e-36 125.2 0.1 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 KNE01925.1 - 4.7e-16 59.2 1.7 1.6e-15 57.6 0.6 2.3 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KNE01925.1 - 0.022 14.5 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family Rad60-SLD PF11976.8 KNE01925.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Mito_carr PF00153.27 KNE01927.1 - 9.3e-60 198.6 2.4 4.4e-22 77.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RIIa PF02197.17 KNE01927.1 - 0.062 13.0 0.0 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit DUF1741 PF08427.10 KNE01928.1 - 3.7e-06 26.8 0.8 7.7e-06 25.7 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) Gemini_AL3 PF01407.17 KNE01928.1 - 0.1 12.4 1.3 2.9 7.8 0.2 2.6 2 0 0 2 2 2 0 Geminivirus AL3 protein DPPIV_N PF00930.21 KNE01929.1 - 2.5e-60 204.1 2.8 3.9e-60 203.5 2.8 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KNE01929.1 - 2.6e-45 154.5 1.1 5.2e-45 153.5 1.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KNE01929.1 - 1.6e-06 28.9 0.0 0.00098 19.8 0.0 3.3 2 1 1 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KNE01929.1 - 7.7e-06 25.7 0.0 1.7e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KNE01929.1 - 0.00085 19.0 0.1 0.0034 17.1 0.1 1.9 2 0 0 2 2 2 1 Putative esterase PAF-AH_p_II PF03403.13 KNE01929.1 - 0.055 12.0 0.1 0.12 10.8 0.0 1.5 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 KNE01929.1 - 0.098 11.9 0.0 0.39 9.9 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Noc2 PF03715.13 KNE01930.1 - 2e-122 408.2 9.4 3.3e-122 407.4 6.7 2.1 2 0 0 2 2 2 1 Noc2p family Nop14 PF04147.12 KNE01930.1 - 0.0022 16.3 0.2 0.0022 16.3 0.2 3.4 2 2 1 3 3 3 1 Nop14-like family O-FucT PF10250.9 KNE01930.1 - 0.016 15.0 0.4 0.037 13.7 0.0 1.8 2 0 0 2 2 2 0 GDP-fucose protein O-fucosyltransferase Zn_clus PF00172.18 KNE01931.1 - 6.6e-05 23.0 5.5 0.00014 21.9 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_2 PF13639.6 KNE01932.1 - 2.2e-10 40.7 7.2 4.9e-10 39.6 7.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KNE01932.1 - 1.7e-08 34.0 4.8 1.7e-08 34.0 4.8 2.4 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4 PF00097.25 KNE01932.1 - 1.4e-07 31.3 5.7 2.8e-07 30.3 5.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KNE01932.1 - 2.3e-07 30.7 1.8 2.3e-07 30.7 1.8 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KNE01932.1 - 3.6e-07 29.9 6.8 7.4e-07 28.9 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KNE01932.1 - 2.3e-06 27.4 4.7 4.6e-06 26.5 4.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KNE01932.1 - 3.1e-06 27.4 11.9 3.4e-06 27.2 8.2 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KNE01932.1 - 0.00012 21.9 3.7 0.00024 20.9 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KNE01932.1 - 0.00061 19.8 1.8 0.0012 18.8 1.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KNE01932.1 - 0.00063 19.5 5.0 0.0014 18.5 5.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KNE01932.1 - 0.0019 17.8 3.5 0.004 16.8 3.5 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Rtf2 PF04641.12 KNE01932.1 - 0.0026 17.2 0.1 0.0042 16.5 0.1 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3H2C3 PF17122.5 KNE01932.1 - 0.31 11.1 4.0 1.2 9.2 4.0 2.1 1 1 0 1 1 1 0 Zinc-finger C1_1 PF00130.22 KNE01932.1 - 0.36 10.7 5.1 0.17 11.8 2.5 1.8 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FANCL_C PF11793.8 KNE01932.1 - 0.69 10.1 7.1 5.6 7.2 7.1 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.7 KNE01932.1 - 0.71 10.0 5.8 1.5 9.0 5.8 1.6 1 0 0 1 1 1 0 RING-variant domain C2 PF00168.30 KNE01934.1 - 1.3e-60 202.1 3.0 3.4e-17 62.6 0.0 4.7 4 0 0 4 4 4 4 C2 domain SMP_LBD PF17047.5 KNE01934.1 - 0.013 14.9 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 Synaptotagmin-like mitochondrial-lipid-binding domain RNA_pol_Rpb2_6 PF00562.28 KNE01935.1 - 7.5e-124 413.7 0.1 7.5e-124 413.7 0.1 1.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KNE01935.1 - 2.2e-58 197.1 0.4 3.2e-58 196.6 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KNE01935.1 - 6.1e-38 130.4 0.5 1.3e-37 129.3 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KNE01935.1 - 1.2e-33 115.4 0.1 3.3e-33 113.9 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 KNE01935.1 - 7e-26 90.3 0.3 2.8e-25 88.4 0.2 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KNE01935.1 - 2.8e-18 65.8 0.0 6e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KNE01935.1 - 2.9e-14 53.3 1.4 7.8e-14 52.0 1.4 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Ribonuc_red_lgC PF02867.15 KNE01937.1 - 4.1e-176 586.6 0.0 5e-176 586.3 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KNE01937.1 - 1.2e-19 70.0 0.1 3.4e-19 68.6 0.1 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain LepB_GAP_C PF18227.1 KNE01937.1 - 0.087 13.4 0.1 0.42 11.2 0.0 2.1 2 0 0 2 2 2 0 LepB GAP domain C-terminal subdomain Tfb2 PF03849.14 KNE01938.1 - 1.3e-136 455.3 0.0 1.7e-136 454.9 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KNE01938.1 - 2.5e-22 79.1 0.6 5.6e-22 77.9 0.6 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KNE01938.1 - 0.00014 22.0 0.0 0.00027 21.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Response_reg PF00072.24 KNE01940.1 - 3.7e-11 43.2 0.0 4.7e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain GTP1_OBG PF01018.22 KNE01941.1 - 4.4e-37 127.1 1.5 1.5e-26 92.8 1.7 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 KNE01941.1 - 4.2e-19 68.7 0.0 8.8e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KNE01941.1 - 1.1e-07 31.6 0.0 1.5e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 KNE01941.1 - 0.006 16.0 0.0 0.015 14.7 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Dynamin_N PF00350.23 KNE01941.1 - 0.014 15.4 0.0 0.037 14.1 0.0 1.8 1 1 0 1 1 1 0 Dynamin family Ras PF00071.22 KNE01941.1 - 0.098 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Ras family DEAD PF00270.29 KNE01942.1 - 2.1e-43 148.1 0.0 3.7e-43 147.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNE01942.1 - 9.6e-30 103.2 0.0 3.7e-29 101.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNE01942.1 - 0.0002 21.4 0.4 0.0013 18.7 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit LSDAT_prok PF18171.1 KNE01942.1 - 0.063 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote MIF4G_like_2 PF09090.11 KNE01942.1 - 0.094 12.2 1.1 0.18 11.2 1.1 1.6 1 1 0 1 1 1 0 MIF4G like DUF202 PF02656.15 KNE01943.1 - 2.3e-13 50.4 0.5 2.3e-13 50.4 0.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MIG-14_Wnt-bd PF06664.12 KNE01943.1 - 0.0027 17.0 2.5 0.0034 16.6 2.5 1.1 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion LRRC37AB_C PF14914.6 KNE01943.1 - 0.15 12.0 0.5 0.37 10.7 0.4 1.7 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain TFIIB PF00382.19 KNE01945.1 - 4.6e-47 157.9 0.2 1.9e-23 82.2 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KNE01945.1 - 1.1e-21 77.1 0.4 1.1e-21 77.1 0.4 3.3 2 1 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 KNE01945.1 - 5.5e-07 29.0 0.2 1.3e-06 27.8 0.2 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 KNE01945.1 - 0.00048 19.9 0.0 0.83 9.4 0.0 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain DUF5316 PF17247.2 KNE01945.1 - 0.15 12.1 0.1 0.37 10.8 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5316) SDA1 PF05285.12 KNE01946.1 - 1.1e-98 330.9 42.8 1.2e-98 330.8 36.6 2.2 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 KNE01946.1 - 1.7e-24 85.9 0.4 1e-23 83.4 0.1 2.5 2 0 0 2 2 2 1 NUC130/3NT domain HMG_box PF00505.19 KNE01947.1 - 2.3e-09 37.6 1.1 2.3e-09 37.6 1.1 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KNE01947.1 - 2.1e-06 28.2 0.3 9.3e-06 26.1 0.3 2.2 1 0 0 1 1 1 1 HMG-box domain Med25_NR-box PF11244.8 KNE01948.1 - 0.034 14.6 0.3 0.043 14.2 0.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 25 C-terminal NR box-containing Acyl_transf_1 PF00698.21 KNE01949.1 - 1.6e-11 44.3 0.0 2e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Acyl transferase domain FTHFS PF01268.19 KNE01951.1 - 8.7e-257 852.8 0.2 1.2e-256 852.3 0.2 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KNE01951.1 - 5.3e-63 211.1 2.4 7.4e-63 210.6 0.9 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KNE01951.1 - 2.1e-37 127.9 0.7 4.6e-37 126.8 0.7 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain CbiA PF01656.23 KNE01951.1 - 0.026 14.6 0.0 0.15 12.1 0.0 2.2 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1573 PF07610.11 KNE01952.1 - 0.037 14.0 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) PTR2 PF00854.21 KNE01953.1 - 8.8e-95 317.8 9.8 1e-93 314.3 9.8 2.0 1 1 0 1 1 1 1 POT family DUF4134 PF13572.6 KNE01953.1 - 0.0031 17.8 0.2 0.026 14.8 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4134) DUF2104 PF09877.9 KNE01953.1 - 1.7 8.9 7.2 0.49 10.7 1.1 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2104) NDUF_B12 PF08122.12 KNE01953.1 - 2.6 8.2 4.9 1.9 8.6 1.6 2.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Peptidase_M3 PF01432.20 KNE01956.1 - 2.5e-147 491.8 5.1 2.5e-147 491.8 5.1 1.7 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M50B PF13398.6 KNE01956.1 - 0.046 13.4 1.8 0.48 10.0 0.3 2.2 2 0 0 2 2 2 0 Peptidase M50B-like Peptidase_M48_N PF16491.5 KNE01956.1 - 0.32 10.9 2.6 1.2 9.0 0.0 2.6 3 0 0 3 3 3 0 CAAX prenyl protease N-terminal, five membrane helices HGTP_anticodon PF03129.20 KNE01957.1 - 5.2e-23 81.0 0.0 5.2e-23 81.0 0.0 2.5 4 0 0 4 4 4 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KNE01957.1 - 4.7e-08 33.2 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) FMO-like PF00743.19 KNE01959.1 - 1.1e-13 50.5 0.6 6.1e-10 38.1 0.4 2.9 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KNE01959.1 - 2.2e-08 33.7 0.4 2e-06 27.2 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KNE01959.1 - 8.6e-08 31.8 0.0 0.00018 20.9 0.0 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KNE01959.1 - 1e-06 28.2 0.0 0.00065 19.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KNE01959.1 - 1.8e-05 24.8 0.0 4.5e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KNE01959.1 - 0.0066 16.4 0.0 0.7 9.9 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KNE01959.1 - 0.14 11.3 0.0 0.48 9.6 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 KNE01959.1 - 0.24 11.4 0.0 3.2 7.8 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ABA_GPCR PF12430.8 KNE01961.1 - 1.1e-47 162.2 11.9 2.2e-47 161.1 11.9 1.5 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KNE01961.1 - 1.7e-13 50.4 0.0 4.8e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal Renin_r PF07850.14 KNE01961.1 - 0.027 15.0 0.5 0.18 12.4 0.0 2.7 2 1 0 2 2 2 0 Renin receptor-like protein ERGIC_N PF13850.6 KNE01961.1 - 0.032 14.6 0.7 0.26 11.7 0.0 2.9 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) FA_desaturase PF00487.24 KNE01961.1 - 0.11 12.4 0.5 0.36 10.6 0.5 1.9 1 1 0 1 1 1 0 Fatty acid desaturase Mhr1 PF12829.7 KNE01962.1 - 1.4e-20 73.2 0.2 2.6e-20 72.3 0.2 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Zn_clus PF00172.18 KNE01963.1 - 1.6e-05 24.9 12.7 2.4e-05 24.3 12.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KNE01963.1 - 0.0019 17.3 0.9 0.0071 15.4 0.1 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain Radical_SAM PF04055.21 KNE01965.1 - 8.9e-21 75.0 0.0 2.7e-20 73.4 0.0 1.9 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 KNE01965.1 - 2.5e-20 72.6 0.0 5.7e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.25 KNE01965.1 - 5.9e-14 52.5 0.0 3e-13 50.2 0.0 2.2 2 1 0 2 2 2 1 Flavodoxin Glycos_transf_1 PF00534.20 KNE01966.1 - 3.4e-27 95.1 1.1 4e-14 52.5 0.0 2.4 3 0 0 3 3 3 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KNE01966.1 - 1.3e-13 51.3 0.0 2.9e-13 50.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KNE01966.1 - 9.9e-08 32.5 0.0 2.3e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_20 PF00982.21 KNE01966.1 - 0.00048 18.9 0.0 0.00068 18.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 ALG11_N PF15924.5 KNE01966.1 - 0.0044 17.1 0.5 0.93 9.5 0.2 2.7 2 1 0 2 2 2 2 ALG11 mannosyltransferase N-terminus Glyco_trans_4_4 PF13579.6 KNE01966.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain DUF1992 PF09350.10 KNE01967.1 - 4e-15 55.7 0.7 1.4e-14 54.0 0.1 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1992) UPF0016 PF01169.19 KNE01968.1 - 3.9e-38 129.6 27.1 1.1e-18 67.3 7.5 3.1 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 KNE01968.1 - 0.0031 17.3 4.7 0.013 15.3 0.1 2.4 2 0 0 2 2 2 2 Putative manganese efflux pump Med8 PF10232.9 KNE01969.1 - 3e-12 46.7 10.6 5.9e-12 45.7 10.6 1.5 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Allexi_40kDa PF05549.11 KNE01969.1 - 1.8 8.0 5.4 0.58 9.6 0.8 2.1 2 1 1 3 3 3 0 Allexivirus 40kDa protein NpwBP PF12622.7 KNE01970.1 - 9.5e-07 29.5 11.9 6.9e-05 23.5 11.9 2.7 1 1 0 1 1 1 1 mRNA biogenesis factor Mito_carr PF00153.27 KNE01971.1 - 5e-76 250.7 0.7 5.4e-28 96.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3535 PF12054.8 KNE01972.1 - 7e-114 381.4 4.9 1.6e-113 380.3 1.2 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KNE01972.1 - 2.2e-65 220.7 0.0 6.1e-65 219.2 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KNE01972.1 - 5.7e-19 68.5 0.0 1.8e-18 66.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 KNE01972.1 - 8.4e-14 50.5 3.5 0.43 11.0 0.0 9.6 8 1 1 9 9 9 3 HEAT repeat Vac14_Fab1_bd PF12755.7 KNE01972.1 - 3.1e-07 30.9 0.0 0.046 14.3 0.0 4.3 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 KNE01972.1 - 0.00098 19.5 7.1 0.073 13.5 0.0 5.4 6 0 0 6 6 6 1 HEAT repeats RTP1_C1 PF10363.9 KNE01972.1 - 0.014 15.6 0.0 5 7.3 0.0 4.1 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 ERCC3_RAD25_C PF16203.5 KNE01972.1 - 0.069 12.4 0.0 0.16 11.1 0.0 1.6 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Cnd1 PF12717.7 KNE01972.1 - 0.35 10.9 7.6 0.14 12.2 0.4 3.7 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Ccdc124 PF06244.12 KNE01974.1 - 1.9e-32 112.5 23.2 2.2e-31 109.1 23.2 2.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 Menin PF05053.13 KNE01974.1 - 5.8 5.1 14.4 7 4.9 14.4 1.1 1 0 0 1 1 1 0 Menin UDG PF03167.19 KNE01975.1 - 0.11 12.5 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily HMGL-like PF00682.19 KNE01976.1 - 2.3e-83 279.8 0.4 3.1e-83 279.4 0.4 1.2 1 0 0 1 1 1 1 HMGL-like Ribosomal_60s PF00428.19 KNE01976.1 - 0.0076 16.8 1.7 0.019 15.6 1.7 1.7 1 0 0 1 1 1 1 60s Acidic ribosomal protein Neur_chan_memb PF02932.16 KNE01977.1 - 0.4 10.7 3.4 0.57 10.2 3.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mur_ligase_M PF08245.12 KNE01978.1 - 3e-06 27.4 0.0 0.00019 21.5 0.0 2.7 1 1 0 1 1 1 1 Mur ligase middle domain DUF592 PF04574.13 KNE01978.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF592) PCI PF01399.27 KNE01979.1 - 0.00057 20.4 0.8 0.0019 18.7 0.2 2.4 2 1 0 2 2 2 1 PCI domain THP2 PF09432.10 KNE01979.1 - 0.064 13.3 0.5 0.064 13.3 0.5 2.7 2 1 1 3 3 3 0 Tho complex subunit THP2 Pkinase PF00069.25 KNE01980.1 - 6.8e-67 225.6 0.1 1.1e-66 224.9 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE01980.1 - 9.1e-38 130.0 0.0 1.7e-37 129.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNE01980.1 - 3.3e-06 26.6 0.0 7e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KNE01980.1 - 0.049 13.0 0.6 0.15 11.4 0.1 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SUV3_C PF12513.8 KNE01981.1 - 9.4e-15 54.3 0.5 2.3e-14 53.0 0.5 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 KNE01981.1 - 2.2e-13 50.5 0.0 6.4e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_18 PF13238.6 KNE01982.1 - 4.1e-12 46.8 0.0 5.8e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 KNE01982.1 - 7.4e-09 35.9 0.0 1e-08 35.5 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 KNE01982.1 - 1e-08 35.5 0.0 1.2e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KNE01982.1 - 2.8e-05 24.5 0.0 4.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain dNK PF01712.19 KNE01982.1 - 7.3e-05 22.7 0.1 0.021 14.7 0.0 2.2 1 1 1 2 2 2 1 Deoxynucleoside kinase APS_kinase PF01583.20 KNE01982.1 - 9.4e-05 22.4 0.0 0.00013 21.9 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase T2SSE PF00437.20 KNE01982.1 - 0.00032 19.9 0.0 0.053 12.6 0.1 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein Cytidylate_kin PF02224.18 KNE01982.1 - 0.0004 20.2 0.0 0.0057 16.4 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase AAA PF00004.29 KNE01982.1 - 0.00058 20.3 0.0 0.00092 19.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KNE01982.1 - 0.0012 18.1 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 KNE01982.1 - 0.0018 18.6 0.0 0.0032 17.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KNE01982.1 - 0.0028 17.9 0.1 0.0034 17.7 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KNE01982.1 - 0.0057 16.4 0.0 0.008 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KNE01982.1 - 0.0087 16.5 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KNE01982.1 - 0.009 16.0 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KNE01982.1 - 0.014 15.8 0.1 0.025 14.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 KNE01982.1 - 0.017 15.4 0.1 0.036 14.4 0.1 1.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Thymidylate_kin PF02223.17 KNE01982.1 - 0.02 14.5 0.0 0.78 9.4 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase ABC_tran PF00005.27 KNE01982.1 - 0.024 15.2 0.1 0.046 14.2 0.0 1.5 1 1 1 2 2 1 0 ABC transporter PRK PF00485.18 KNE01982.1 - 0.025 14.3 0.0 0.29 10.8 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RuvB_N PF05496.12 KNE01982.1 - 0.046 13.5 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KNE01982.1 - 0.052 13.5 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain PhoH PF02562.16 KNE01982.1 - 0.055 12.9 0.1 0.094 12.1 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein ADK PF00406.22 KNE01982.1 - 0.058 13.5 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 Adenylate kinase SRP54 PF00448.22 KNE01982.1 - 0.076 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain tRNA_lig_kinase PF08303.11 KNE01982.1 - 0.077 13.1 0.0 0.52 10.4 0.0 2.0 2 0 0 2 2 2 0 tRNA ligase kinase domain CoaE PF01121.20 KNE01982.1 - 0.12 12.1 0.1 0.35 10.5 0.0 1.7 2 0 0 2 2 2 0 Dephospho-CoA kinase RNA_helicase PF00910.22 KNE01982.1 - 0.15 12.4 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 KNE01982.1 - 0.16 11.1 0.4 0.3 10.3 0.4 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KNE01982.1 - 0.17 11.6 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain adh_short PF00106.25 KNE01984.1 - 3.1e-13 49.6 0.1 6.7e-05 22.4 0.0 3.3 3 0 0 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 KNE01984.1 - 3.3e-05 23.5 0.0 0.007 15.9 0.0 3.0 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 KNE01985.1 - 1.9e-96 322.4 1.8 3e-96 321.8 1.8 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KNE01985.1 - 1e-45 154.3 1.2 4.7e-45 152.2 0.4 2.4 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KNE01985.1 - 3e-05 23.7 0.9 5.8e-05 22.8 0.3 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KNE01985.1 - 0.26 11.2 4.0 1.5 8.7 0.2 3.2 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FLILHELTA PF10306.9 KNE01986.1 - 2.8e-26 91.7 0.3 5e-26 90.9 0.3 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 KNE01986.1 - 0.073 13.6 0.5 0.18 12.4 0.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) Pkinase PF00069.25 KNE01987.1 - 1.3e-64 218.1 0.0 1.6e-64 217.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE01987.1 - 2.3e-23 82.8 0.0 3.2e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNE01987.1 - 5.8e-05 22.6 0.0 0.00018 20.9 0.0 1.7 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KNE01987.1 - 0.00026 21.0 0.0 0.002 18.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KNE01987.1 - 0.046 13.3 0.2 0.08 12.5 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 KNE01987.1 - 0.094 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RR_TM4-6 PF06459.12 KNE01988.1 - 2.7 7.7 12.7 5.7 6.7 12.7 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KNE01988.1 - 9.6 4.8 9.5 17 4.0 9.5 1.4 1 0 0 1 1 1 0 Presenilin AA_permease PF00324.21 KNE01991.1 - 4.4e-116 388.3 41.4 5.2e-116 388.1 41.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KNE01991.1 - 4.1e-28 98.4 43.0 5.5e-28 98.0 43.0 1.1 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 KNE01992.1 - 5.5e-31 107.9 0.0 6.7e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE01992.1 - 1.3e-18 67.2 0.0 1.7e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNE01992.1 - 0.0012 18.2 0.0 0.0065 15.8 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 KNE01993.1 - 1.7e-60 204.6 0.2 9.7e-60 202.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE01993.1 - 1.3e-29 103.3 0.9 2.6e-27 95.7 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KNE01993.1 - 0.0022 17.0 0.1 0.0032 16.5 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FA_hydroxylase PF04116.13 KNE01994.1 - 6e-23 81.6 22.6 8.1e-23 81.2 17.9 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily Porphobil_deam PF01379.20 KNE01995.1 - 2.8e-73 245.8 0.0 3.6e-73 245.4 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KNE01995.1 - 6.8e-21 74.4 0.3 1.3e-20 73.6 0.3 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Myb_DNA-binding PF00249.31 KNE01995.1 - 0.087 13.0 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain ERCC4 PF02732.15 KNE01999.1 - 6.6e-20 71.9 0.0 2.4e-19 70.0 0.0 2.1 2 0 0 2 2 2 1 ERCC4 domain RMI1_N PF08585.12 KNE02000.1 - 4.3e-13 49.5 0.0 5.9e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 RecQ mediated genome instability protein MTHFR PF02219.17 KNE02001.1 - 1.2e-102 343.1 0.0 3.8e-102 341.5 0.0 1.8 3 0 0 3 3 3 1 Methylenetetrahydrofolate reductase ATG27 PF09451.10 KNE02002.1 - 7.8e-46 157.1 0.1 1e-45 156.7 0.1 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KNE02002.1 - 0.0024 18.0 0.1 0.0048 17.0 0.1 1.5 1 0 0 1 1 1 1 Cation-independent mannose-6-phosphate receptor repeat Striatin PF08232.12 KNE02003.1 - 0.013 16.1 2.8 0.018 15.6 2.8 1.1 1 0 0 1 1 1 0 Striatin family DUF1664 PF07889.12 KNE02003.1 - 0.022 14.8 0.6 0.035 14.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KNE02003.1 - 0.032 14.3 3.8 0.051 13.6 3.8 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4094 PF13334.6 KNE02003.1 - 0.035 14.5 0.6 0.066 13.6 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) CLU_N PF15044.6 KNE02003.1 - 0.037 14.4 0.5 0.055 13.8 0.5 1.3 1 0 0 1 1 1 0 Mitochondrial function, CLU-N-term DUF948 PF06103.11 KNE02003.1 - 0.11 12.8 3.9 0.12 12.6 2.9 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Synaptobrevin PF00957.21 KNE02003.1 - 0.51 10.2 2.9 7.8 6.4 0.4 2.2 1 1 1 2 2 2 0 Synaptobrevin Phage_holin_7_1 PF16081.5 KNE02003.1 - 0.58 10.3 4.0 0.81 9.9 4.0 1.2 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DivIC PF04977.15 KNE02003.1 - 1.1 9.1 5.9 1.4 8.7 2.0 2.1 2 0 0 2 2 2 0 Septum formation initiator PAXNEB PF05625.11 KNE02004.1 - 7.1e-89 298.5 0.0 9.6e-89 298.1 0.0 1.1 1 0 0 1 1 1 1 PAXNEB protein DUF3786 PF12654.7 KNE02004.1 - 0.18 11.4 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) Serinc PF03348.15 KNE02005.1 - 7.5e-142 473.2 12.4 8.4e-142 473.1 12.4 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Ceramidase PF05875.12 KNE02005.1 - 0.0029 17.1 0.8 0.0029 17.1 0.8 2.4 2 1 0 3 3 3 1 Ceramidase Mpv17_PMP22 PF04117.12 KNE02005.1 - 0.0074 16.5 3.6 0.033 14.4 3.6 2.2 1 0 0 1 1 1 1 Mpv17 / PMP22 family ATP-synt_G PF04718.15 KNE02006.1 - 8.4e-29 100.3 0.4 9.9e-29 100.1 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit DEAD PF00270.29 KNE02007.1 - 3.7e-40 137.5 0.1 7.9e-40 136.5 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNE02007.1 - 4.8e-29 100.9 3.6 5e-29 100.9 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNE02007.1 - 1e-06 28.9 0.0 1e-06 28.9 0.0 1.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KNE02007.1 - 0.0085 14.9 0.1 0.093 11.5 0.0 2.3 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 KNE02007.1 - 0.046 14.0 0.5 0.25 11.6 0.5 2.2 1 1 0 1 1 1 0 AAA domain GP11 PF08677.10 KNE02007.1 - 0.11 12.0 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 GP11 baseplate wedge protein Sof1 PF04158.14 KNE02007.1 - 2.8 8.3 12.8 0.075 13.3 4.8 2.4 2 0 0 2 2 2 0 Sof1-like domain Ribonucleas_3_3 PF14622.6 KNE02008.1 - 5.3e-25 88.0 0.8 8.1e-25 87.5 0.8 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like TfoX_C PF04994.13 KNE02008.1 - 0.022 14.9 0.2 0.2 11.8 0.0 2.4 3 0 0 3 3 3 0 TfoX C-terminal domain TRAPP PF04051.16 KNE02010.1 - 0.039 13.7 0.0 0.042 13.6 0.0 1.0 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component Mito_carr PF00153.27 KNE02011.1 - 7.7e-51 170.0 7.7 2.2e-16 59.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PepSY_2 PF13670.6 KNE02011.1 - 0.093 12.7 0.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain UPF0223 PF05256.12 KNE02012.1 - 0.035 14.4 0.1 0.096 13.0 0.1 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0223) GA-like PF17573.2 KNE02012.1 - 0.16 11.9 1.6 11 6.1 0.9 2.9 2 1 0 2 2 2 0 GA-like domain GDPD_2 PF13653.6 KNE02019.1 - 0.1 13.1 0.7 0.21 12.1 0.7 1.6 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Mito_carr PF00153.27 KNE02020.1 - 2.7e-55 184.3 2.4 1.1e-20 73.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 KNE02020.1 - 0.26 11.7 5.6 31 5.0 0.9 3.1 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Ribosomal_S19 PF00203.21 KNE02021.1 - 4.1e-32 109.9 0.2 4.5e-32 109.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_60s PF00428.19 KNE02022.1 - 5.2e-27 94.3 13.3 6.1e-27 94.1 13.3 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein FTA4 PF13093.6 KNE02023.1 - 1.6e-22 80.4 24.3 3.2e-21 76.2 24.3 2.4 1 1 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 STAR_dimer PF16544.5 KNE02023.1 - 0.68 9.5 5.6 1.8 8.2 0.4 3.6 3 0 0 3 3 3 0 Homodimerisation region of STAR domain protein SmAKAP PF15127.6 KNE02023.1 - 1.6 10.0 8.3 8.2 7.7 1.0 2.5 2 0 0 2 2 2 0 Small membrane A-kinase anchor protein RSN1_7TM PF02714.15 KNE02025.1 - 2e-76 256.9 28.3 2e-76 256.9 28.3 2.1 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KNE02025.1 - 7.1e-37 126.6 0.4 7.1e-37 126.6 0.4 3.0 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KNE02025.1 - 4.8e-29 101.8 0.0 1.7e-28 100.1 0.0 1.9 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Arv1 PF04161.13 KNE02026.1 - 2.6e-54 184.6 4.7 2.6e-54 184.6 4.7 1.5 2 0 0 2 2 2 1 Arv1-like family zf-ribbon_3 PF13248.6 KNE02026.1 - 0.095 12.1 0.1 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain NMD3 PF04981.13 KNE02026.1 - 0.14 11.6 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 NMD3 family Phage_Coat_Gp8 PF05371.12 KNE02026.1 - 0.4 10.5 2.0 0.59 9.9 0.4 2.1 2 0 0 2 2 2 0 Phage major coat protein, Gp8 zf-CCCH_4 PF18044.1 KNE02027.1 - 2.4e-09 36.8 3.4 4.9e-09 35.8 3.4 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KNE02027.1 - 7.4e-08 32.1 2.7 1.4e-07 31.2 2.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KNE02027.1 - 3.2e-07 30.2 8.3 6.6e-07 29.2 8.3 1.6 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 KNE02027.1 - 0.0011 19.7 0.2 0.0026 18.4 0.2 1.6 1 0 0 1 1 1 1 Torus domain Topoisom_bac PF01131.20 KNE02028.1 - 2.2e-105 353.0 0.0 2.6e-105 352.8 0.0 1.0 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KNE02028.1 - 1e-17 64.2 0.0 2.4e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 Toprim domain SET PF00856.28 KNE02029.1 - 5e-17 62.8 0.0 7.3e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 SET domain ApbA_C PF08546.11 KNE02030.1 - 2.2e-32 111.9 0.1 3.3e-32 111.3 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KNE02030.1 - 3.9e-30 104.5 0.0 5.5e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TfuA PF07812.12 KNE02030.1 - 0.011 15.4 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 TfuA-like protein Sacchrp_dh_NADP PF03435.18 KNE02030.1 - 0.033 14.5 0.3 0.15 12.3 0.0 2.3 2 1 1 3 3 3 0 Saccharopine dehydrogenase NADP binding domain CoaE PF01121.20 KNE02031.1 - 3e-54 183.4 0.1 3.7e-54 183.1 0.1 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KNE02031.1 - 0.00016 22.2 0.2 0.0015 19.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KNE02031.1 - 0.0021 18.3 0.0 0.0075 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KNE02031.1 - 0.0046 17.1 0.1 0.018 15.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain SKI PF01202.22 KNE02031.1 - 0.023 14.8 0.2 0.43 10.7 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase UPF0154 PF03672.13 KNE02031.1 - 0.17 11.9 0.0 13 5.9 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) PI3_PI4_kinase PF00454.27 KNE02032.1 - 2.6e-45 155.2 0.0 5.1e-45 154.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KNE02032.1 - 4.2e-34 117.6 7.9 6.4e-21 74.6 0.1 3.9 3 1 0 3 3 3 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 KNE02032.1 - 6.9e-17 61.7 0.1 1.4e-16 60.7 0.1 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF2857 PF11198.8 KNE02032.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) DUF2025 PF09634.10 KNE02033.1 - 0.0025 17.8 0.1 0.0055 16.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2025) His_Phos_1 PF00300.22 KNE02033.1 - 0.012 15.4 0.0 0.07 12.8 0.0 2.1 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) LmjF365940-deam PF14421.6 KNE02034.1 - 0.03 13.9 0.1 0.034 13.8 0.1 1.1 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases dCMP_cyt_deam_1 PF00383.23 KNE02034.1 - 0.048 13.6 0.1 0.056 13.3 0.1 1.2 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Peptidase_M24 PF00557.24 KNE02035.1 - 2.9e-49 167.6 0.0 3.6e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KNE02035.1 - 1.7e-15 57.1 5.5 1.7e-15 57.1 5.5 1.7 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KNE02035.1 - 0.025 14.7 3.9 0.063 13.4 3.9 1.7 1 0 0 1 1 1 0 MYND finger Phosphodiest PF01663.22 KNE02036.1 - 2e-11 44.1 2.3 1.3e-07 31.5 0.3 2.5 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KNE02036.1 - 4.9e-05 22.8 0.4 8.1e-05 22.1 0.4 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KNE02036.1 - 0.019 14.4 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 Sulfatase DUF229 PF02995.17 KNE02036.1 - 0.067 11.8 0.1 0.099 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF4003 PF13170.6 KNE02036.1 - 0.074 12.4 3.7 0.12 11.7 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4003) zf-C2H2_2 PF12756.7 KNE02037.1 - 6.9e-33 113.0 1.8 1.4e-32 112.0 1.8 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) SAGA-Tad1 PF12767.7 KNE02037.1 - 0.019 14.7 0.5 0.038 13.7 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF678 PF05077.12 KNE02037.1 - 0.079 13.1 0.0 0.26 11.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF678) DNA_pol_A_exo1 PF01612.20 KNE02038.1 - 4.9e-42 143.6 0.0 9.7e-42 142.6 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 KNE02038.1 - 3.4e-06 26.9 0.0 8.5e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.12 KNE02038.1 - 3.9e-05 24.2 0.2 3.9e-05 24.2 0.2 2.5 2 0 0 2 2 2 1 PMC2NT (NUC016) domain Glyoxalase_4 PF13669.6 KNE02038.1 - 0.15 12.3 0.0 0.37 11.1 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Methyltransf_11 PF08241.12 KNE02039.1 - 0.028 15.1 0.0 0.062 13.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 KNE02039.1 - 0.045 13.2 0.1 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_25 PF13649.6 KNE02039.1 - 0.048 14.4 0.0 0.14 12.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain His_biosynth PF00977.21 KNE02040.1 - 7.4e-43 146.6 0.1 4.1e-42 144.2 0.1 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KNE02040.1 - 1.8e-18 67.0 0.0 4.7e-18 65.6 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KNE02040.1 - 2e-10 40.6 0.0 3.4e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 KNE02040.1 - 1.1e-06 28.7 0.1 0.0034 17.3 0.0 2.4 2 0 0 2 2 2 2 SNO glutamine amidotransferase family ThiG PF05690.14 KNE02040.1 - 0.011 15.1 0.1 0.021 14.1 0.1 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG BPL_N PF09825.9 KNE02040.1 - 0.025 13.7 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Bystin PF05291.11 KNE02041.1 - 4.8e-120 400.3 0.0 6.9e-120 399.7 0.0 1.1 1 0 0 1 1 1 1 Bystin MatE PF01554.18 KNE02042.1 - 1.5e-59 200.3 31.5 1.8e-34 118.7 13.0 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KNE02042.1 - 1.9e-07 31.3 5.0 1.9e-07 31.3 5.0 3.5 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain Rcd1 PF04078.13 KNE02043.1 - 3.7e-114 380.4 0.7 1.2e-113 378.7 0.7 1.7 1 1 0 1 1 1 1 Cell differentiation family, Rcd1-like HMA PF00403.26 KNE02044.1 - 1.9e-10 41.0 0.1 4e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain SOG2 PF10428.9 KNE02045.1 - 1.3e-51 176.4 29.7 5.9e-29 101.7 4.5 4.0 2 1 0 3 3 3 2 RAM signalling pathway protein LRR_8 PF13855.6 KNE02045.1 - 3.5e-15 55.5 6.1 1.7e-08 34.1 2.2 3.3 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KNE02045.1 - 9.9e-15 54.4 4.5 2.6e-06 27.6 0.0 4.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KNE02045.1 - 0.00017 21.7 8.0 16 6.5 0.1 5.9 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_9 PF14580.6 KNE02045.1 - 0.018 14.6 0.2 0.066 12.7 0.1 2.0 1 1 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 KNE02045.1 - 0.098 12.8 4.1 9.2 6.6 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich repeat TauD PF02668.16 KNE02046.1 - 1.2e-33 117.1 0.0 3.4e-33 115.6 0.0 1.6 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CN_hydrolase PF00795.22 KNE02047.1 - 3e-44 151.3 0.0 6.5e-44 150.2 0.0 1.5 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KNE02047.1 - 7.2e-24 84.2 0.0 2.3e-23 82.6 0.0 1.6 1 1 0 1 1 1 1 NAD synthase Abhydrolase_1 PF00561.20 KNE02048.1 - 8.4e-16 58.4 0.1 2.9e-15 56.6 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNE02048.1 - 1.4e-13 52.0 0.0 1.9e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNE02048.1 - 1.8e-10 40.5 0.0 2.9e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 KNE02048.1 - 0.057 12.9 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) TFIIE_alpha PF02002.17 KNE02048.1 - 0.1 12.5 0.4 0.27 11.1 0.1 1.9 2 0 0 2 2 2 0 TFIIE alpha subunit PGAP1 PF07819.13 KNE02048.1 - 0.11 12.2 0.0 0.54 9.9 0.0 2.0 2 1 0 2 2 2 0 PGAP1-like protein dCMP_cyt_deam_1 PF00383.23 KNE02049.1 - 1.9e-18 66.2 0.0 2.6e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KNE02049.1 - 2.3e-10 40.3 0.0 4.5e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase Inv-AAD PF18785.1 KNE02049.1 - 5.4e-05 23.1 0.1 8.3e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase Bd3614-deam PF14439.6 KNE02049.1 - 5.7e-05 23.2 0.6 0.00016 21.8 0.6 1.7 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC2 PF18772.1 KNE02049.1 - 0.19 11.8 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 APOBEC2 DPBB_1 PF03330.18 KNE02050.1 - 7e-10 39.0 0.0 1.9e-09 37.7 0.0 1.8 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KNE02050.1 - 0.017 15.0 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 Barwin family Ssl1 PF04056.14 KNE02051.1 - 7.6e-62 208.5 0.1 1.1e-61 208.0 0.1 1.3 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 KNE02051.1 - 2.9e-24 85.1 19.6 3.5e-24 84.8 11.3 2.6 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 KNE02051.1 - 2.5e-12 47.4 0.0 5e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KNE02051.1 - 0.00029 21.1 0.0 0.00049 20.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-HIT PF04438.16 KNE02051.1 - 0.088 12.7 0.5 0.088 12.7 0.5 3.9 4 0 0 4 4 4 0 HIT zinc finger zinc_ribbon_15 PF17032.5 KNE02051.1 - 0.5 11.2 18.7 1.4 9.7 5.7 2.5 2 0 0 2 2 2 0 zinc-ribbon family DZR PF12773.7 KNE02051.1 - 3 7.9 19.8 0.81 9.8 2.7 3.3 2 1 0 2 2 2 0 Double zinc ribbon Spt5-NGN PF03439.13 KNE02052.1 - 3.5e-24 84.5 0.0 9.6e-24 83.1 0.0 1.8 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 KNE02052.1 - 1.5e-22 80.4 15.1 1.5e-22 80.4 15.1 3.1 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 KNE02052.1 - 2.8e-09 36.6 21.4 0.0016 18.3 1.3 6.0 6 0 0 6 6 6 4 KOW motif ProQ_C PF17516.2 KNE02052.1 - 0.0074 15.7 5.3 0.41 10.1 0.2 3.4 3 0 0 3 3 3 2 ProQ C-terminal domain Pribosyltran PF00156.27 KNE02054.1 - 4.6e-17 62.0 0.0 6.8e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KNE02054.1 - 0.0015 18.0 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_3 PF15610.6 KNE02054.1 - 0.22 10.8 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 PRTase ComF-like Dynein_light PF01221.18 KNE02055.1 - 1.7e-28 98.7 0.0 1.9e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3646 PF12362.8 KNE02055.1 - 0.12 12.7 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal Ectatomin PF06457.11 KNE02055.1 - 0.19 11.6 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 Ectatomin Med13_N PF11597.8 KNE02056.1 - 1e-52 179.5 3.9 2.3e-52 178.3 3.9 1.6 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal Med13_C PF06333.12 KNE02056.1 - 1.1e-15 57.8 3.7 1.1e-15 57.8 3.7 4.4 3 2 1 4 4 4 1 Mediator complex subunit 13 C-terminal domain GAS PF13851.6 KNE02057.1 - 0.0001 21.7 8.1 0.0001 21.7 8.1 1.8 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Arfaptin PF06456.13 KNE02057.1 - 0.019 14.5 1.2 0.019 14.5 1.2 2.9 3 0 0 3 3 3 0 Arfaptin-like domain MnmE_helical PF12631.7 KNE02057.1 - 0.091 12.9 6.0 2 8.6 0.0 2.3 1 1 1 2 2 2 0 MnmE helical domain T4SS PF07996.11 KNE02057.1 - 0.18 12.2 2.1 0.43 11.0 2.1 1.6 1 0 0 1 1 1 0 Type IV secretion system proteins DUF4200 PF13863.6 KNE02057.1 - 3.1 8.2 15.1 4.4 7.7 6.0 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Cyclin_N PF00134.23 KNE02058.1 - 1.8e-46 157.0 0.2 4.1e-45 152.6 0.5 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KNE02058.1 - 5.6e-33 113.6 0.0 2.8e-32 111.3 0.0 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF1770 PF08589.10 KNE02058.1 - 5.6 8.0 8.4 17 6.4 4.6 2.8 2 1 0 2 2 2 0 Fungal protein of unknown function (DUF1770) RTT107_BRCT_5 PF16770.5 KNE02059.1 - 7.1e-25 86.8 0.7 5.6e-21 74.3 0.3 3.7 3 0 0 3 3 3 2 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 KNE02059.1 - 5e-24 84.5 1.7 2e-05 24.9 0.1 6.0 6 0 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KNE02059.1 - 2.8e-23 81.6 0.0 6.3e-13 48.5 0.0 4.8 4 1 0 4 4 4 3 twin BRCT domain BRCT_2 PF16589.5 KNE02059.1 - 4.4e-16 59.1 0.4 2.7e-05 24.5 0.0 4.9 5 0 0 5 5 5 4 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_6 PF16771.5 KNE02059.1 - 1.9e-14 53.8 1.4 1.9e-14 53.8 1.4 2.4 2 1 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KNE02059.1 - 1.8e-05 24.7 0.0 1.5 8.9 0.0 5.0 5 0 0 5 5 5 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KNE02059.1 - 5.4e-05 23.4 0.0 0.0015 18.8 0.0 3.4 3 0 0 3 3 3 1 DNA ligase 3 BRCT domain Seryl_tRNA_N PF02403.22 KNE02059.1 - 0.046 13.9 5.4 0.1 12.8 5.4 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ENTH PF01417.20 KNE02060.1 - 1.4e-42 144.6 0.1 2.7e-42 143.8 0.1 1.5 1 0 0 1 1 1 1 ENTH domain UIM PF02809.20 KNE02060.1 - 0.00016 21.4 12.4 0.0096 15.8 0.6 3.1 3 0 0 3 3 3 2 Ubiquitin interaction motif CCDC106 PF15794.5 KNE02062.1 - 1.7 8.3 10.5 3 7.5 10.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Striatin PF08232.12 KNE02062.1 - 4.6 7.8 10.7 12 6.5 10.7 1.6 1 0 0 1 1 1 0 Striatin family Raftlin PF15250.6 KNE02062.1 - 8.7 5.0 9.3 13 4.4 9.3 1.2 1 0 0 1 1 1 0 Raftlin Glyco_hydro_76 PF03663.14 KNE02063.1 - 1.6e-159 531.3 22.5 1.9e-159 531.1 22.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 PRD1_DD PF11087.8 KNE02063.1 - 1.1 8.9 4.1 2.5 7.9 4.1 1.5 1 0 0 1 1 1 0 PRD1 phage membrane DNA delivery PX PF00787.24 KNE02064.1 - 8.5e-15 54.7 0.4 8.5e-15 54.7 0.4 2.1 2 0 0 2 2 2 1 PX domain NES_C_h PF18208.1 KNE02064.1 - 0.022 15.0 2.5 0.022 15.0 0.2 2.2 2 0 0 2 2 2 0 Nicking enzyme C-terminal middle helical domain Nuc_N PF14448.6 KNE02064.1 - 0.083 12.8 0.4 0.17 11.8 0.4 1.5 1 0 0 1 1 1 0 Nuclease N terminal DUF16 PF01519.16 KNE02064.1 - 0.16 12.5 3.4 4 8.0 0.4 3.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 EST1 PF10374.9 KNE02064.1 - 6.4 7.4 7.3 13 6.4 0.0 3.2 3 1 0 3 3 3 0 Telomerase activating protein Est1 Lung_7-TM_R PF06814.13 KNE02065.1 - 2.8e-57 194.2 17.2 5.1e-57 193.4 17.2 1.4 1 1 0 1 1 1 1 Lung seven transmembrane receptor PCI PF01399.27 KNE02066.1 - 6.7e-09 36.2 1.0 6.7e-09 36.2 1.0 2.2 2 0 0 2 2 2 1 PCI domain Rpn9_C PF18261.1 KNE02066.1 - 4.6e-05 22.9 0.1 0.00018 21.1 0.0 2.1 2 0 0 2 2 2 1 Rpn9 C-terminal helix PX PF00787.24 KNE02067.1 - 1.1e-17 64.0 0.7 3.8e-17 62.3 0.5 2.0 1 1 0 1 1 1 1 PX domain Cytochrom_B562 PF07361.11 KNE02067.1 - 1.1 10.0 4.6 5.3 7.8 0.0 3.5 3 0 0 3 3 3 0 Cytochrome b562 Mannosyl_trans3 PF11051.8 KNE02069.1 - 3.6e-87 292.2 0.0 6e-87 291.5 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative LCM PF04072.14 KNE02070.1 - 7.3e-26 91.3 0.0 1.3e-25 90.5 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Clr5 PF14420.6 KNE02071.1 - 0.014 15.6 1.6 0.019 15.2 1.6 1.2 1 0 0 1 1 1 0 Clr5 domain Methyltransf_11 PF08241.12 KNE02074.1 - 1.1e-11 45.2 0.0 2.3e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNE02074.1 - 2.4e-09 37.8 0.0 5.5e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNE02074.1 - 1.1e-07 31.8 0.0 1.7e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNE02074.1 - 7.7e-07 29.1 0.1 1.7e-06 28.0 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNE02074.1 - 1.9e-06 28.6 0.1 3.5e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KNE02074.1 - 0.0013 18.4 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 KNE02074.1 - 0.079 11.9 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) HIGH_NTase1 PF05636.11 KNE02075.1 - 0.072 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase TAFII28 PF04719.14 KNE02076.1 - 1.1e-28 99.1 0.0 3e-28 97.7 0.0 1.7 1 1 0 1 1 1 1 hTAFII28-like protein conserved region DUF3419 PF11899.8 KNE02077.1 - 5.2e-151 503.2 0.0 8.1e-151 502.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 KNE02077.1 - 2.8e-08 33.8 0.0 2.8e-07 30.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNE02077.1 - 4.4e-08 33.8 0.1 1.5e-05 25.7 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNE02077.1 - 1e-06 29.3 0.0 3.1e-05 24.6 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNE02077.1 - 1.4e-05 25.7 0.0 0.00041 21.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KNE02077.1 - 0.01 15.2 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KNE02077.1 - 0.15 11.4 0.0 0.58 9.4 0.0 1.8 2 0 0 2 2 2 0 O-methyltransferase domain CM_2 PF01817.21 KNE02078.1 - 0.0048 17.2 0.3 0.56 10.6 0.2 2.9 2 1 0 2 2 2 2 Chorismate mutase type II DnaJ PF00226.31 KNE02079.1 - 6.7e-11 42.2 1.0 2.5e-10 40.3 1.0 2.0 1 1 0 1 1 1 1 DnaJ domain Peripla_BP_7 PF18610.1 KNE02079.1 - 0.076 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Periplasmic binding protein domain Amidohydro_1 PF01979.20 KNE02080.1 - 2.2e-13 50.2 0.2 5.3e-13 49.0 0.2 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KNE02080.1 - 3.4e-08 33.4 0.4 1e-06 28.5 0.0 2.8 2 1 1 3 3 3 1 Amidohydrolase family Glucosamine_iso PF01182.20 KNE02082.1 - 1.5e-17 64.3 0.0 3.9e-17 62.9 0.0 1.6 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hexokinase_2 PF03727.16 KNE02084.1 - 5.9e-48 163.4 0.0 7.9e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KNE02084.1 - 3e-31 108.9 0.0 4.8e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Hexokinase RHD3 PF05879.12 KNE02085.1 - 3.5e-253 842.1 13.4 4.3e-253 841.8 13.4 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KNE02085.1 - 1.7e-07 30.8 0.1 3.2e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 KNE02085.1 - 9.8e-05 22.4 0.1 0.00038 20.5 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KNE02085.1 - 0.00034 20.9 2.8 0.00075 19.8 0.0 3.0 4 0 0 4 4 4 1 AAA domain Dynamin_N PF00350.23 KNE02085.1 - 0.00053 20.1 0.0 0.00053 20.1 0.0 2.7 3 0 0 3 3 3 1 Dynamin family PBP1_TM PF14812.6 KNE02085.1 - 0.0062 16.9 1.7 0.024 15.0 1.7 2.0 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_22 PF13401.6 KNE02085.1 - 0.027 14.7 0.4 4.7 7.5 0.0 3.1 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.6 KNE02085.1 - 0.046 14.1 1.3 0.22 11.9 0.0 2.8 3 1 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.22 KNE02085.1 - 0.062 13.7 0.0 0.21 12.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase O-FucT PF10250.9 KNE02085.1 - 0.068 12.9 0.9 0.13 11.9 0.3 1.7 2 0 0 2 2 2 0 GDP-fucose protein O-fucosyltransferase AAA_14 PF13173.6 KNE02085.1 - 0.071 13.1 1.3 0.5 10.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.27 KNE02086.1 - 2.8e-61 206.5 0.1 4.8e-61 205.7 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KNE02086.1 - 1.2e-22 79.7 0.0 2.4e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KNE02086.1 - 3.1e-15 56.0 0.0 6.5e-09 35.7 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KNE02086.1 - 4.2e-12 46.3 0.2 9.9e-12 45.1 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KNE02086.1 - 0.00086 19.1 0.0 0.0029 17.4 0.0 1.9 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KNE02086.1 - 0.0025 17.9 0.1 0.0068 16.5 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Av_adeno_fibre PF06536.11 KNE02086.1 - 0.062 13.2 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 Avian adenovirus fibre, N-terminal Metallophos_2 PF12850.7 KNE02086.1 - 0.082 13.1 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain UAA PF08449.11 KNE02087.1 - 2.8e-74 250.0 19.4 3.4e-74 249.8 19.4 1.0 1 0 0 1 1 1 1 UAA transporter family Borrelia_P13 PF05628.12 KNE02087.1 - 0.027 14.4 2.5 1 9.3 0.8 2.3 2 0 0 2 2 2 0 Borrelia membrane protein P13 EamA PF00892.20 KNE02087.1 - 7.9 6.7 28.4 3 8.0 9.9 2.4 2 0 0 2 2 2 0 EamA-like transporter family ABC_membrane PF00664.23 KNE02088.1 - 1.1e-54 186.0 42.4 1.4e-34 120.0 21.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KNE02088.1 - 5.2e-45 153.3 2.2 4.9e-27 95.1 0.0 3.4 3 1 0 3 3 2 2 ABC transporter SMC_N PF02463.19 KNE02088.1 - 6.9e-08 32.2 13.8 0.00052 19.5 1.3 4.4 4 1 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KNE02088.1 - 3.3e-07 29.9 0.4 0.0019 17.9 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KNE02088.1 - 6.3e-05 23.0 1.0 0.077 12.9 1.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KNE02088.1 - 0.00076 19.5 0.8 0.44 10.6 0.1 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KNE02088.1 - 0.00097 18.6 0.5 0.82 9.0 0.0 2.9 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_16 PF13191.6 KNE02088.1 - 0.0025 18.2 2.3 0.39 11.1 0.0 3.7 4 0 0 4 4 3 1 AAA ATPase domain AAA_21 PF13304.6 KNE02088.1 - 0.0066 16.3 9.1 2.9 7.6 0.1 4.0 4 1 1 5 5 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KNE02088.1 - 0.012 16.1 2.5 2.2 8.9 0.1 3.2 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 KNE02088.1 - 0.014 15.1 0.2 1 9.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KNE02088.1 - 0.016 14.5 0.1 0.46 9.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 KNE02088.1 - 0.052 13.8 4.0 12 6.2 0.0 4.1 3 1 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KNE02088.1 - 0.052 13.3 1.9 5.6 6.7 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein T2SSE PF00437.20 KNE02088.1 - 0.064 12.3 0.1 3.4 6.6 0.1 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein APS_kinase PF01583.20 KNE02088.1 - 0.075 12.9 1.6 6.7 6.6 0.1 3.7 4 0 0 4 4 3 0 Adenylylsulphate kinase AAA_23 PF13476.6 KNE02088.1 - 0.085 13.3 0.1 0.085 13.3 0.1 4.2 3 1 1 4 4 3 0 AAA domain PRK PF00485.18 KNE02088.1 - 0.22 11.3 1.7 5.5 6.7 0.2 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family cobW PF02492.19 KNE02088.1 - 0.23 11.0 1.1 0.79 9.3 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KNE02088.1 - 0.52 10.5 2.4 41 4.4 0.0 3.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 KNE02088.1 - 0.77 9.8 0.0 0.77 9.8 0.0 2.9 3 1 1 4 4 2 0 Helicase HerA, central domain CDC45 PF02724.14 KNE02088.1 - 6 5.0 11.7 4.6 5.4 4.1 2.3 2 0 0 2 2 2 0 CDC45-like protein PTR2 PF00854.21 KNE02092.1 - 4.3e-90 302.4 11.7 2.7e-89 299.8 11.7 1.9 1 1 0 1 1 1 1 POT family Pkinase PF00069.25 KNE02093.1 - 1.1e-74 251.1 0.0 1.6e-74 250.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE02093.1 - 6.6e-36 123.9 0.0 1e-35 123.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KNE02093.1 - 6.3e-30 103.3 1.9 7.4e-14 51.9 0.1 3.0 3 0 0 3 3 3 2 FHA domain Yop-YscD_cpl PF16697.5 KNE02093.1 - 7.6e-11 42.2 0.0 2.4e-06 27.7 0.0 3.0 2 1 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 KNE02093.1 - 1.4e-08 34.4 0.0 3.8e-08 33.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KNE02093.1 - 8.4e-05 22.0 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FHA_2 PF17913.1 KNE02093.1 - 0.00019 21.6 0.1 0.078 13.2 0.0 3.6 2 1 0 2 2 2 1 FHA domain APH PF01636.23 KNE02093.1 - 0.00028 20.9 0.1 0.041 13.8 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KNE02093.1 - 0.0092 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kinesin PF00225.23 KNE02094.1 - 3e-81 272.9 0.1 4.6e-81 272.3 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KNE02094.1 - 3.3e-19 69.3 0.0 1.1e-18 67.6 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding Tim29 PF10171.9 KNE02094.1 - 0.027 14.0 0.3 0.07 12.6 0.2 1.8 2 0 0 2 2 2 0 Translocase of the Inner Mitochondrial membrane 29 COMP PF11598.8 KNE02094.1 - 0.33 11.5 6.0 7.8 7.1 0.7 3.1 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein FlxA PF14282.6 KNE02094.1 - 0.7 9.9 3.7 23 5.0 0.1 2.5 2 0 0 2 2 2 0 FlxA-like protein GrpE PF01025.19 KNE02094.1 - 1.9 8.1 7.2 2.4 7.8 5.9 1.8 1 1 0 1 1 1 0 GrpE DUF5082 PF16888.5 KNE02094.1 - 3.5 7.9 9.8 20 5.5 0.1 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF5082) TruD PF01142.18 KNE02097.1 - 9.5e-72 242.1 3.8 5.8e-69 232.9 0.8 3.2 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Rhodanese PF00581.20 KNE02098.1 - 1e-14 54.9 0.0 1.1e-06 29.1 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain WD40 PF00400.32 KNE02099.1 - 8.7e-33 111.8 28.3 3.6e-08 33.9 0.5 9.0 8 2 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.8 KNE02099.1 - 9.6e-07 27.8 0.8 0.00095 17.9 0.1 3.3 2 1 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KNE02099.1 - 0.00057 20.1 2.1 5.7 7.3 0.0 4.1 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KNE02099.1 - 0.014 14.1 0.1 0.39 9.4 0.0 2.3 2 0 0 2 2 2 0 Nup133 N terminal like Ist1 PF03398.14 KNE02101.1 - 7.3e-57 191.9 0.3 8.8e-57 191.6 0.3 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF5535 PF17687.1 KNE02101.1 - 0.00019 21.5 0.0 0.00037 20.6 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5535) Pkinase PF00069.25 KNE02103.1 - 6.5e-49 166.7 0.9 1e-44 152.9 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNE02103.1 - 4.5e-18 65.5 0.0 1.1e-17 64.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KNE02103.1 - 0.0073 16.3 0.1 0.027 14.4 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KNE02103.1 - 0.019 14.3 0.9 0.17 11.2 0.0 2.5 2 1 0 2 2 2 0 Kinase-like EAP30 PF04157.16 KNE02103.1 - 0.04 13.2 0.4 0.095 12.0 0.2 1.7 2 0 0 2 2 2 0 EAP30/Vps36 family DUF3991 PF13154.6 KNE02103.1 - 0.074 13.4 0.2 0.52 10.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) Sof1 PF04158.14 KNE02105.1 - 8.2e-34 115.8 16.0 1.4e-33 115.0 16.0 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KNE02105.1 - 2.4e-29 100.9 9.2 1.5e-05 25.7 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNE02105.1 - 4.6e-07 30.1 0.0 0.089 13.1 0.1 3.4 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain NIF PF03031.18 KNE02106.1 - 7e-53 178.6 0.1 9.6e-53 178.1 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Pyr_redox_2 PF07992.14 KNE02108.1 - 6.9e-62 209.3 3.2 8.4e-62 209.0 2.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KNE02108.1 - 3e-32 111.2 2.3 8e-32 109.8 0.1 2.4 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KNE02108.1 - 5.7e-17 62.1 6.4 6.8e-15 55.4 0.5 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KNE02108.1 - 2.2e-11 43.6 4.3 1.4e-09 37.7 0.5 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KNE02108.1 - 3.3e-08 33.3 0.0 6.6e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KNE02108.1 - 9.9e-06 24.5 3.9 0.0071 15.1 0.4 3.3 3 1 0 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.21 KNE02108.1 - 4.8e-05 22.8 2.1 0.028 13.7 0.1 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KNE02108.1 - 8.8e-05 22.5 1.8 0.019 14.9 0.2 2.6 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KNE02108.1 - 0.00011 21.5 10.4 0.00019 20.7 1.9 2.7 2 2 0 2 2 2 2 Glucose inhibited division protein A K_oxygenase PF13434.6 KNE02108.1 - 0.00012 21.4 0.0 0.00025 20.3 0.0 1.5 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 KNE02108.1 - 0.00067 19.1 2.0 0.19 11.1 0.0 3.1 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KNE02108.1 - 0.0024 17.0 1.9 0.0061 15.7 1.9 1.7 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KNE02108.1 - 0.0059 16.8 0.9 0.0059 16.8 0.9 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KNE02108.1 - 0.01 15.5 0.8 0.01 15.5 0.8 2.6 3 1 0 3 3 3 0 FAD dependent oxidoreductase adh_short PF00106.25 KNE02108.1 - 0.014 14.9 0.1 0.036 13.5 0.1 1.6 1 0 0 1 1 1 0 short chain dehydrogenase FAD_binding_3 PF01494.19 KNE02108.1 - 0.018 14.3 2.0 0.69 9.1 0.2 2.5 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 KNE02108.1 - 0.064 13.7 0.3 1.3 9.5 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 KNE02108.1 - 0.19 10.7 0.3 0.52 9.3 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 KNE02108.1 - 0.2 11.2 2.8 0.57 9.7 0.2 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 KNE02108.1 - 0.23 10.7 1.6 0.3 10.3 0.2 1.9 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 KNE02108.1 - 0.63 10.0 0.0 0.63 10.0 0.0 2.6 3 0 0 3 3 2 0 FAD-NAD(P)-binding Nucleo_P87 PF07267.11 KNE02109.1 - 0.014 14.2 0.9 0.02 13.8 0.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 GEN1_C PF18380.1 KNE02109.1 - 0.41 11.6 4.3 0.3 12.0 1.6 2.1 1 1 1 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain CLP1_P PF16575.5 KNE02110.1 - 3.3e-32 111.8 0.0 5.2e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 KNE02110.1 - 6.2e-25 87.9 0.0 1.6e-24 86.5 0.0 1.7 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 KNE02110.1 - 6e-23 80.9 0.1 1.4e-22 79.7 0.1 1.6 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor FtsK_SpoIIIE PF01580.18 KNE02110.1 - 0.0044 16.4 0.0 0.0075 15.6 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family SRPRB PF09439.10 KNE02110.1 - 0.0098 15.3 0.3 0.19 11.2 0.1 2.7 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit DAP3 PF10236.9 KNE02110.1 - 0.014 14.6 0.0 0.031 13.4 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 G-alpha PF00503.20 KNE02110.1 - 0.038 13.2 0.2 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit Roc PF08477.13 KNE02110.1 - 0.042 14.1 0.1 0.094 12.9 0.1 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_35 PF14516.6 KNE02110.1 - 0.056 12.3 0.0 0.087 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain PduV-EutP PF10662.9 KNE02110.1 - 0.067 12.9 0.1 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KNE02110.1 - 0.098 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein TniB PF05621.11 KNE02110.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 KNE02110.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Terminase_GpA PF05876.12 KNE02110.1 - 0.23 9.9 0.0 0.34 9.4 0.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) PTPA PF03095.15 KNE02111.1 - 4.5e-117 390.8 0.5 5.2e-117 390.6 0.5 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein F_actin_bind PF08919.10 KNE02111.1 - 0.029 14.5 0.2 0.052 13.6 0.2 1.4 1 0 0 1 1 1 0 F-actin binding LETM1 PF07766.13 KNE02112.1 - 8.9e-10 38.4 2.4 0.0035 16.7 0.0 3.2 3 0 0 3 3 3 3 LETM1-like protein MOZ_SAS PF01853.18 KNE02113.1 - 9.4e-80 266.5 0.1 1.8e-79 265.5 0.1 1.5 1 1 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KNE02113.1 - 2.3e-22 78.3 0.2 4.9e-22 77.3 0.2 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KNE02113.1 - 3.6e-20 71.6 0.4 8.7e-20 70.4 0.4 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KNE02113.1 - 0.0073 16.7 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain WD40 PF00400.32 KNE02114.1 - 7.8e-29 99.3 11.2 1.4e-05 25.8 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNE02114.1 - 0.00017 21.8 0.2 4.9 7.5 0.0 4.5 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KNE02114.1 - 0.0014 17.4 0.4 1.5 7.3 0.1 3.8 3 2 1 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KNE02114.1 - 0.0032 16.8 0.0 0.021 14.2 0.0 2.3 2 0 0 2 2 2 1 WD40-like domain Glyco_hydro38C2 PF17677.1 KNE02114.1 - 0.008 16.3 0.0 0.041 14.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain PI31_Prot_C PF08577.11 KNE02118.1 - 3.9e-14 53.6 9.9 3.9e-14 53.6 9.9 2.5 1 1 1 2 2 2 1 PI31 proteasome regulator UPF0193 PF05250.11 KNE02118.1 - 0.0052 16.6 0.1 0.0069 16.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) DUF3013 PF11217.8 KNE02118.1 - 0.048 13.5 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3013) Glucosamine_iso PF01182.20 KNE02120.1 - 1.5e-51 175.4 0.0 2.4e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase ABC_membrane PF00664.23 KNE02123.1 - 1.1e-53 182.7 41.3 5.9e-37 127.8 13.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KNE02123.1 - 7.9e-45 152.7 0.3 1.7e-28 99.9 0.0 3.3 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KNE02123.1 - 2e-08 34.4 4.1 0.028 14.3 0.0 4.7 4 1 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KNE02123.1 - 4.4e-08 32.8 6.6 0.00061 19.3 0.6 4.1 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KNE02123.1 - 3.6e-05 23.4 1.5 0.046 13.5 0.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KNE02123.1 - 0.00016 22.3 11.2 0.052 14.0 0.7 3.9 4 0 0 4 4 3 2 AAA domain MMR_HSR1 PF01926.23 KNE02123.1 - 0.00052 20.1 1.8 0.3 11.2 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 KNE02123.1 - 0.00053 19.8 3.1 0.02 14.6 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KNE02123.1 - 0.0006 19.7 0.8 0.83 9.5 0.3 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 KNE02123.1 - 0.00087 19.8 0.0 0.96 10.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KNE02123.1 - 0.0013 19.2 0.0 0.093 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KNE02123.1 - 0.0035 17.1 0.6 0.48 10.1 0.1 2.7 3 0 0 3 3 3 1 AAA domain ATP_bind_1 PF03029.17 KNE02123.1 - 0.013 15.3 1.4 4.7 6.9 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein cobW PF02492.19 KNE02123.1 - 0.015 14.9 1.0 0.085 12.4 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 KNE02123.1 - 0.018 14.3 0.9 3 7.1 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin Dynamin_N PF00350.23 KNE02123.1 - 0.02 15.0 2.9 1.2 9.2 0.8 2.6 2 0 0 2 2 2 0 Dynamin family AAA_22 PF13401.6 KNE02123.1 - 0.024 14.9 2.5 8.1 6.7 0.2 3.3 3 0 0 3 3 3 0 AAA domain Vps51 PF08700.11 KNE02123.1 - 0.031 14.4 0.4 0.031 14.4 0.4 2.3 2 0 0 2 2 1 0 Vps51/Vps67 ATPase_2 PF01637.18 KNE02123.1 - 0.1 12.5 0.5 0.7 9.8 0.0 2.6 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 KNE02123.1 - 0.11 12.5 0.4 0.8 9.7 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Gp138_N PF18352.1 KNE02123.1 - 0.19 11.8 0.0 0.47 10.6 0.0 1.6 1 0 0 1 1 1 0 Phage protein Gp138 N-terminal domain T2SSE PF00437.20 KNE02123.1 - 0.36 9.8 2.0 0.31 10.1 0.2 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein UCH PF00443.29 KNE02124.1 - 6.6e-55 186.4 0.6 6.6e-55 186.4 0.6 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KNE02124.1 - 3.6e-18 66.2 2.0 3.6e-18 66.2 2.0 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KNE02124.1 - 5.9e-12 45.7 10.5 5.9e-12 45.7 10.5 2.6 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_C98 PF15499.6 KNE02124.1 - 0.00052 19.6 3.2 0.12 11.9 0.1 3.3 3 0 0 3 3 3 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase zf-C6H2 PF15801.5 KNE02124.1 - 5.1 7.5 11.9 32 4.9 6.7 3.0 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Phosducin PF02114.16 KNE02126.1 - 6e-12 45.1 1.9 7.7e-12 44.7 1.9 1.2 1 0 0 1 1 1 1 Phosducin Exog_C PF18026.1 KNE02126.1 - 0.096 12.8 1.6 0.27 11.3 1.6 1.8 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain Efg1 PF10153.9 KNE02126.1 - 0.44 10.9 8.4 0.076 13.4 3.6 2.1 2 0 0 2 2 2 0 rRNA-processing protein Efg1 DUF866 PF05907.13 KNE02127.1 - 1e-59 200.9 2.2 1.2e-59 200.7 2.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Ribosomal_L44 PF00935.19 KNE02127.1 - 0.0054 17.2 1.8 2.1 8.9 0.2 2.2 2 0 0 2 2 2 2 Ribosomal protein L44 Zn-ribbon_8 PF09723.10 KNE02127.1 - 0.015 15.4 1.4 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 KNE02127.1 - 0.06 13.3 0.8 0.18 11.7 0.8 1.8 1 1 0 1 1 1 0 SprT-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KNE02127.1 - 1.2 9.1 5.3 1.8 8.6 4.1 1.9 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Cytochrom_C PF00034.21 KNE02128.1 - 6.4e-11 43.2 0.0 9.4e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KNE02128.1 - 2.5e-07 30.9 1.7 2.6e-06 27.6 1.7 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KNE02128.1 - 0.037 13.7 0.5 0.19 11.4 0.2 2.0 2 0 0 2 2 2 0 Cytochrome c-550 domain MA3 PF02847.17 KNE02129.1 - 5.3e-17 61.8 0.7 2e-16 59.9 0.3 2.2 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 KNE02129.1 - 1.3e-06 28.2 0.4 3.1e-06 27.0 0.4 1.7 1 0 0 1 1 1 1 MIF4G domain Spec3 PF15795.5 KNE02129.1 - 0.053 14.1 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 Ectodermal ciliogenesis protein PPR_2 PF13041.6 KNE02130.1 - 1.1e-10 41.5 0.0 9.5e-08 32.1 0.0 2.8 2 0 0 2 2 2 2 PPR repeat family CTP_transf_like PF01467.26 KNE02131.1 - 2.2e-06 27.9 0.0 5.2e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Cytidylyltransferase-like ANAPC4 PF12896.7 KNE02131.1 - 0.027 14.0 0.1 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 USP7_C2 PF14533.6 KNE02132.1 - 1.5e-54 184.8 2.0 1.2e-53 181.9 0.4 2.7 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 KNE02132.1 - 3.5e-43 148.0 0.9 7.2e-43 146.9 0.9 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 KNE02132.1 - 5.9e-38 130.5 2.1 1.7e-30 106.1 0.2 3.2 4 0 0 4 4 4 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 KNE02132.1 - 1.2e-18 67.8 0.0 9e-18 64.9 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KNE02132.1 - 2.4e-07 30.9 0.0 7.9e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 MATH domain 40S_S4_C PF16121.5 KNE02136.1 - 0.18 11.5 0.5 0.33 10.6 0.3 1.6 2 0 0 2 2 2 0 40S ribosomal protein S4 C-terminus Glyco_hydro_17 PF00332.18 KNE02137.1 - 2.5e-07 30.6 0.2 4e-07 29.9 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 SR-25 PF10500.9 KNE02137.1 - 4.9 6.7 8.9 8.1 6.0 8.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rap1-DNA-bind PF09197.10 KNE02138.1 - 3.4e-35 120.9 6.6 9.9e-32 109.8 0.5 2.6 3 0 0 3 3 3 2 Rap1, DNA-binding Rap1_C PF11626.8 KNE02138.1 - 6.3e-11 42.2 0.1 3.8e-10 39.7 0.0 2.4 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 KNE02138.1 - 1.1e-07 31.9 2.3 0.00095 19.3 0.2 2.9 2 0 0 2 2 2 2 Rap1 Myb domain BRCT_2 PF16589.5 KNE02138.1 - 1.6e-06 28.4 0.0 3.6e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Metallophos PF00149.28 KNE02139.1 - 1.1e-12 48.9 0.0 1.9e-12 48.2 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KNE02139.1 - 0.00047 20.4 0.0 0.00079 19.7 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CEP44 PF15007.6 KNE02139.1 - 0.081 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 DUF5383 PF17355.2 KNE02139.1 - 0.085 13.2 0.8 0.16 12.4 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5383) Metallophos_3 PF14582.6 KNE02139.1 - 0.088 12.1 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily RabGAP-TBC PF00566.18 KNE02140.1 - 2.1e-32 112.5 14.8 1.2e-28 100.3 7.5 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain rRNA_proc-arch PF13234.6 KNE02141.1 - 2.8e-77 260.3 0.6 2.8e-77 260.3 0.6 2.0 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 KNE02141.1 - 3.5e-57 192.6 1.1 9.6e-57 191.2 1.1 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KNE02141.1 - 9.7e-19 67.8 0.1 2.8e-17 63.0 0.0 3.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNE02141.1 - 4.5e-07 30.2 0.0 2.2e-06 28.0 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNE02141.1 - 0.00038 20.5 0.0 0.0033 17.5 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KNE02141.1 - 0.031 14.5 0.0 0.12 12.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KNE02141.1 - 0.045 12.8 0.0 0.19 10.7 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein Peptidase_S10 PF00450.22 KNE02143.1 - 9.2e-133 443.7 0.5 1.1e-132 443.4 0.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 KNE02143.1 - 1.4e-24 87.1 0.8 2.2e-24 86.4 0.8 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Pkinase PF00069.25 KNE02144.1 - 3.6e-36 124.9 0.0 4.4e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE02144.1 - 1.1e-19 70.7 0.1 1.6e-19 70.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KNE02144.1 - 5.6e-05 22.6 1.3 0.00015 21.2 1.3 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KNE02144.1 - 0.0015 17.9 0.1 0.0021 17.5 0.1 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KNE02144.1 - 0.0021 18.0 0.0 0.042 13.8 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family SHMT PF00464.19 KNE02147.1 - 2.1e-206 685.2 0.0 2.5e-206 684.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KNE02147.1 - 6.4e-05 22.3 0.1 0.00042 19.6 0.0 2.3 2 1 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KNE02147.1 - 0.035 13.4 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family VPS11_C PF12451.8 KNE02147.1 - 0.11 12.7 0.1 20 5.5 0.0 2.7 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal Med16 PF11635.8 KNE02148.1 - 1.8e-199 664.4 0.0 2.4e-199 664.0 0.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 16 Phage_holin_3_7 PF05449.11 KNE02149.1 - 0.0032 17.4 0.0 0.0032 17.4 0.0 1.0 1 0 0 1 1 1 1 Putative 3TM holin, Phage_holin_3 HSM3_C PF18794.1 KNE02150.1 - 2.2e-07 30.6 0.1 6.3e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 DNA mismatch repair protein HSM3, C terminal domain Sec7 PF01369.20 KNE02151.1 - 4.1e-20 72.2 0.7 4.1e-20 72.2 0.7 2.5 3 0 0 3 3 3 1 Sec7 domain PH_9 PF15410.6 KNE02151.1 - 0.0085 16.5 2.7 0.032 14.6 0.9 2.9 2 2 0 2 2 2 1 Pleckstrin homology domain Proteasome PF00227.26 KNE02152.1 - 4.1e-39 134.1 0.0 4.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Cmc1 PF08583.10 KNE02153.1 - 5.7e-12 45.5 9.0 8.3e-12 45.0 9.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CtIP_N PF10482.9 KNE02153.1 - 0.032 14.3 7.2 0.037 14.1 7.2 1.2 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain Ndufs5 PF10200.9 KNE02153.1 - 0.2 12.0 4.7 0.26 11.6 4.7 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa zf-TAZ PF02135.16 KNE02154.1 - 0.072 13.6 2.7 0.096 13.2 1.6 1.8 1 1 1 2 2 2 0 TAZ zinc finger E1_dh PF00676.20 KNE02155.1 - 6.5e-119 396.3 0.4 8e-119 396.0 0.4 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KNE02155.1 - 0.0013 18.0 0.0 0.002 17.4 0.0 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Sec63 PF02889.16 KNE02157.1 - 1.3e-136 453.8 1.8 3.6e-73 245.9 0.1 2.6 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KNE02157.1 - 1.1e-40 139.2 0.1 1.8e-25 89.7 0.0 2.8 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 KNE02157.1 - 2.3e-25 89.6 0.1 3.3e-15 56.5 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KNE02157.1 - 1e-11 45.1 0.2 2.5e-08 34.2 0.0 4.4 3 1 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KNE02157.1 - 1.9e-08 34.6 0.2 3.4e-06 27.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain Helicase_PWI PF18149.1 KNE02157.1 - 5.4e-07 29.8 3.7 2e-06 28.0 3.7 2.1 1 0 0 1 1 1 1 N-terminal helicase PWI domain IstB_IS21 PF01695.17 KNE02157.1 - 0.044 13.5 0.3 7.1 6.3 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_34 PF13872.6 KNE02157.1 - 0.1 11.5 0.0 0.61 8.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 PhoH PF02562.16 KNE02157.1 - 0.12 11.8 0.0 17 4.7 0.0 3.2 3 0 0 3 3 3 0 PhoH-like protein TniB PF05621.11 KNE02157.1 - 0.13 11.7 0.1 1.6 8.1 0.1 2.2 1 1 0 2 2 2 0 Bacterial TniB protein DUF4250 PF14056.6 KNE02157.1 - 0.18 11.8 0.9 0.56 10.2 0.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) DUF4611 PF15387.6 KNE02157.1 - 5.2 7.4 13.0 0.12 12.5 5.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Glycos_transf_3 PF00591.21 KNE02159.1 - 5.3e-80 268.7 0.0 6.5e-80 268.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KNE02159.1 - 1.1e-11 44.4 0.0 2.3e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Cnn_1N PF07989.11 KNE02160.1 - 4.4e-07 30.0 5.1 4.4e-07 30.0 5.1 13.2 6 3 7 13 13 13 2 Centrosomin N-terminal motif 1 APG6_N PF17675.1 KNE02160.1 - 0.00026 21.5 16.0 0.00026 21.5 16.0 10.3 3 2 7 11 11 11 3 Apg6 coiled-coil region Spc110_C PF18520.1 KNE02160.1 - 0.008 15.8 1.6 0.008 15.8 1.6 3.0 3 0 0 3 3 3 1 Spindle pole body component 110 C-terminal domain Cep57_MT_bd PF06657.13 KNE02160.1 - 0.012 16.0 1.1 0.012 16.0 1.1 12.0 4 3 6 13 13 13 0 Centrosome microtubule-binding domain of Cep57 GBR2_CC PF18455.1 KNE02160.1 - 0.64 10.2 7.8 1.8 8.8 0.0 4.4 3 1 1 4 4 4 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain DUF1664 PF07889.12 KNE02160.1 - 1.5 8.9 78.2 0.26 11.3 2.6 9.8 5 3 5 10 10 10 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KNE02160.1 - 1.9 7.8 95.4 1.1 8.6 16.8 6.1 2 2 3 5 5 5 0 Domain of unknown function (DUF4407) Apc13p PF05839.11 KNE02161.1 - 0.0053 16.9 0.3 0.016 15.4 0.1 1.9 2 1 0 2 2 2 1 Apc13p protein RNA_pol_Rpb1_5 PF04998.17 KNE02163.1 - 5.3e-81 272.0 0.2 8.6e-81 271.3 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 KNE02163.1 - 1.6e-80 270.7 0.0 3e-80 269.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 KNE02163.1 - 3.1e-75 252.0 0.0 7.6e-75 250.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KNE02163.1 - 3.6e-39 134.2 0.0 1.2e-38 132.5 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KNE02163.1 - 4.9e-32 110.1 0.1 2.3e-31 107.9 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 DSS1_SEM1 PF05160.13 KNE02164.1 - 3.8e-20 71.7 19.1 4.2e-20 71.5 19.1 1.0 1 0 0 1 1 1 1 DSS1/SEM1 family AAA PF00004.29 KNE02165.1 - 8e-41 139.6 0.0 1.4e-40 138.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KNE02165.1 - 2.3e-16 59.5 0.1 5.2e-16 58.3 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KNE02165.1 - 1.9e-07 30.8 0.0 6.5e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KNE02165.1 - 1.7e-05 25.3 0.3 0.022 15.1 0.1 2.6 1 1 1 2 2 2 2 AAA ATPase domain AAA_2 PF07724.14 KNE02165.1 - 0.0001 22.5 0.0 0.00026 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KNE02165.1 - 0.00068 19.4 0.1 0.0017 18.1 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KNE02165.1 - 0.00093 19.2 0.2 0.0065 16.5 0.2 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KNE02165.1 - 0.0021 18.4 0.4 0.17 12.1 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KNE02165.1 - 0.0043 17.2 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KNE02165.1 - 0.015 14.4 0.0 0.03 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.16 KNE02165.1 - 0.016 14.7 0.1 0.052 13.0 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 KNE02165.1 - 0.02 14.3 0.2 0.046 13.1 0.1 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KNE02165.1 - 0.04 13.7 0.1 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 KNE02165.1 - 0.11 12.2 0.2 0.38 10.5 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KNE02165.1 - 0.24 11.2 1.8 0.68 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain PH_TFIIH PF08567.11 KNE02168.1 - 0.027 14.8 0.0 1.2 9.5 0.0 2.1 1 1 1 2 2 2 0 TFIIH p62 subunit, N-terminal domain Cation_efflux PF01545.21 KNE02170.1 - 6.3e-39 133.8 11.3 6.3e-39 133.8 11.3 2.9 2 1 0 2 2 2 1 Cation efflux family ATP_bind_1 PF03029.17 KNE02171.1 - 2.1e-83 279.8 0.0 2.4e-83 279.6 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 KNE02171.1 - 0.0021 17.1 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 KNE02171.1 - 0.006 16.4 0.0 0.021 14.6 0.0 1.9 3 0 0 3 3 3 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_10 PF12846.7 KNE02171.1 - 0.01 14.8 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain GTP_EFTU PF00009.27 KNE02171.1 - 0.018 14.6 0.0 0.4 10.2 0.0 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KNE02171.1 - 0.038 14.1 0.0 0.32 11.1 0.0 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNE02171.1 - 0.074 13.0 0.1 0.64 9.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KNE02171.1 - 0.077 13.5 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 KNE02171.1 - 0.089 13.2 0.0 0.28 11.6 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_31 PF13614.6 KNE02171.1 - 0.1 12.5 0.0 5.8 6.8 0.0 2.4 1 1 1 2 2 2 0 AAA domain Fer4_NifH PF00142.18 KNE02171.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family KAP_NTPase PF07693.14 KNE02171.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.6 KNE02171.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KNE02171.1 - 0.21 11.3 0.0 0.43 10.3 0.0 1.4 2 0 0 2 2 2 0 AAA domain CTP_synth_N PF06418.14 KNE02177.1 - 0.014 14.8 0.0 0.016 14.5 0.0 1.0 1 0 0 1 1 1 0 CTP synthase N-terminus DUF3211 PF11485.8 KNE02177.1 - 0.02 15.1 0.1 0.021 15.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3211) TIP49 PF06068.13 KNE02180.1 - 1.1e-165 551.1 0.2 1.4e-165 550.7 0.2 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KNE02180.1 - 2.6e-22 78.7 0.2 7.3e-22 77.3 0.1 1.9 2 0 0 2 2 1 1 TIP49 AAA-lid domain RuvB_N PF05496.12 KNE02180.1 - 2e-10 40.6 0.2 5.7e-08 32.7 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KNE02180.1 - 3.8e-10 40.3 0.2 2e-06 28.2 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KNE02180.1 - 8.9e-05 22.8 0.1 0.48 10.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KNE02180.1 - 0.00021 21.7 0.8 0.011 16.1 0.1 2.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KNE02180.1 - 0.00043 20.3 0.6 0.99 9.4 0.0 2.7 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KNE02180.1 - 0.0064 15.8 0.2 0.018 14.4 0.1 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.6 KNE02180.1 - 0.0065 16.5 0.0 1.4 9.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 KNE02180.1 - 0.007 15.8 0.2 0.7 9.2 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KNE02180.1 - 0.019 14.7 0.1 8.8 6.0 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 KNE02180.1 - 0.019 15.3 1.6 5.8 7.2 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KNE02180.1 - 0.02 14.5 0.2 0.046 13.3 0.1 1.6 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 KNE02180.1 - 0.048 13.0 0.0 0.096 12.0 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_28 PF13521.6 KNE02180.1 - 0.055 13.7 0.1 0.19 11.9 0.1 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KNE02180.1 - 0.057 13.3 0.1 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 KNE02180.1 - 0.16 11.5 0.1 3.2 7.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KNE02180.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Sec1 PF00995.23 KNE02181.1 - 1.2e-112 378.0 5.0 1.4e-112 377.9 5.0 1.0 1 0 0 1 1 1 1 Sec1 family Lebercilin PF15619.6 KNE02181.1 - 0.063 12.9 0.2 0.14 11.8 0.2 1.5 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease CMV_US PF08001.11 KNE02184.1 - 0.073 12.3 0.1 0.075 12.3 0.1 1.0 1 0 0 1 1 1 0 CMV US Peptidase_C7 PF01830.18 KNE02188.1 - 0.0024 17.4 0.1 0.0026 17.2 0.1 1.1 1 0 0 1 1 1 1 Peptidase C7 family DUF1168 PF06658.12 KNE02195.1 - 0.024 14.5 16.4 0.026 14.3 16.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) EIIBC-GUT_N PF03612.14 KNE02195.1 - 0.22 11.2 2.8 0.26 11.0 2.8 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus SR-25 PF10500.9 KNE02195.1 - 0.24 11.0 17.1 0.27 10.8 17.1 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Connexin PF00029.19 KNE02195.1 - 1.3 8.7 4.2 1.4 8.6 4.2 1.1 1 0 0 1 1 1 0 Connexin AP3D1 PF06375.11 KNE02195.1 - 1.6 8.9 15.3 1.9 8.7 15.3 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Peptidase_S49_N PF08496.10 KNE02195.1 - 5.4 7.1 11.0 6 6.9 11.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Cpn60_TCP1 PF00118.24 KNE02196.1 - 7.3e-162 539.4 1.8 8.3e-162 539.2 1.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA_16 PF13191.6 KNE02196.1 - 0.013 15.9 0.5 0.044 14.2 0.3 1.9 2 0 0 2 2 2 0 AAA ATPase domain ArenaCapSnatch PF17296.2 KNE02196.1 - 0.076 12.4 0.0 11 5.4 0.0 2.5 2 0 0 2 2 2 0 Arenavirus cap snatching domain LCAT PF02450.15 KNE02197.1 - 0.069 12.3 0.0 0.069 12.3 0.0 1.0 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Ras PF00071.22 KNE02199.1 - 9.4e-56 187.9 0.0 1.1e-55 187.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNE02199.1 - 3.9e-22 78.7 0.0 6.4e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNE02199.1 - 9.3e-08 31.7 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KNE02199.1 - 0.0014 18.2 0.0 0.0037 16.8 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KNE02199.1 - 0.011 15.2 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KNE02199.1 - 0.059 13.3 0.1 0.2 11.5 0.0 1.9 2 1 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 KNE02199.1 - 0.067 12.5 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region zf-CHCC PF10276.9 KNE02201.1 - 1.7e-15 56.8 0.3 2.7e-15 56.1 0.3 1.3 1 0 0 1 1 1 1 Zinc-finger domain zf_C2H2_6 PF18450.1 KNE02201.1 - 0.04 13.6 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 Zinc Finger domain zf-C2H2_3 PF13878.6 KNE02201.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO LrgB PF04172.16 KNE02202.1 - 2.6e-49 167.7 5.9 2.6e-49 167.7 5.9 3.0 3 0 0 3 3 3 1 LrgB-like family LrgA PF03788.14 KNE02202.1 - 0.00068 19.5 5.5 0.00068 19.5 5.5 4.4 4 1 0 4 4 4 1 LrgA family RNase_PH PF01138.21 KNE02203.1 - 2.2e-18 67.0 0.0 4.7e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KNE02203.1 - 5.6e-10 39.1 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Band_7 PF01145.25 KNE02204.1 - 3.2e-29 102.2 0.1 5.3e-29 101.5 0.1 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KNE02204.1 - 1.1e-24 86.2 0.4 2.2e-24 85.3 0.4 1.5 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7_1 PF13421.6 KNE02204.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family Cys_rich_CPCC PF14206.6 KNE02204.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Cysteine-rich CPCC Gly_transf_sug PF04488.15 KNE02205.1 - 1.5e-21 76.8 0.0 2.8e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Acyltransferase PF01553.21 KNE02206.1 - 1.8e-16 60.0 0.1 3.9e-16 58.9 0.1 1.5 1 0 0 1 1 1 1 Acyltransferase CLN3 PF02487.17 KNE02207.1 - 8e-136 453.2 23.5 2.1e-135 451.8 23.5 1.6 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 KNE02207.1 - 2 7.3 32.9 49 2.7 31.9 2.5 1 1 0 1 1 1 0 Major Facilitator Superfamily DAHP_synth_1 PF00793.20 KNE02208.1 - 1.9e-104 348.4 0.0 2.3e-104 348.1 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF218 PF02698.17 KNE02209.1 - 0.0017 18.4 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain HlyIII PF03006.20 KNE02210.1 - 5.1e-49 167.0 17.5 6.2e-49 166.7 17.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF3493 PF11998.8 KNE02210.1 - 0.087 13.0 0.2 0.51 10.5 0.1 2.3 3 0 0 3 3 3 0 Low psii accumulation1 / Rep27 DUF3149 PF11346.8 KNE02210.1 - 0.47 10.1 3.8 1.9 8.2 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3149) NAT PF04768.13 KNE02211.1 - 3.2e-35 121.3 0.1 1.1e-34 119.5 0.0 1.8 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Sld5 PF05916.11 KNE02212.1 - 1.3e-18 67.4 1.1 1.8e-18 67.0 1.1 1.2 1 0 0 1 1 1 1 GINS complex protein Chitin_synth_1 PF01644.17 KNE02213.1 - 1.1e-73 246.5 0.9 1.9e-73 245.8 0.9 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 KNE02213.1 - 1.4e-27 96.6 4.5 3.7e-21 75.3 0.0 2.5 3 0 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.11 KNE02213.1 - 3.2e-24 84.7 0.1 1.7e-23 82.4 0.0 2.2 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 KNE02213.1 - 1.5e-07 31.5 8.3 1.5e-07 31.5 8.3 3.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DUF2157 PF09925.9 KNE02213.1 - 0.0064 16.3 0.0 0.021 14.6 0.0 1.9 1 1 0 1 1 1 1 Predicted membrane protein (DUF2157) RCC1 PF00415.18 KNE02216.1 - 5.1e-64 212.7 9.0 2e-12 47.5 0.2 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KNE02216.1 - 3.9e-34 115.8 27.9 6.1e-08 32.3 0.2 6.9 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Arrestin_C PF02752.22 KNE02219.1 - 5.8e-19 68.9 0.0 1.6e-18 67.4 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KNE02219.1 - 7.3e-11 42.3 0.0 1.8e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KNE02219.1 - 0.02 14.6 0.0 0.054 13.2 0.0 1.7 2 0 0 2 2 2 0 Arrestin_N terminal like SNARE PF05739.19 KNE02220.1 - 1.2e-12 47.6 0.2 2.4e-12 46.7 0.2 1.5 1 0 0 1 1 1 1 SNARE domain Peptidase_M28 PF04389.17 KNE02220.1 - 0.074 12.7 0.1 0.28 10.8 0.0 2.0 2 0 0 2 2 2 0 Peptidase family M28 CLZ PF16526.5 KNE02220.1 - 0.94 9.9 9.2 3.1 8.2 2.0 3.4 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3450 PF11932.8 KNE02220.1 - 1.6 8.0 11.8 0.18 11.1 4.8 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) SUR7 PF06687.12 KNE02221.1 - 1.3e-17 64.2 21.3 2.1e-17 63.5 21.3 1.4 1 0 0 1 1 1 1 SUR7/PalI family Herpes_LMP1 PF05297.11 KNE02221.1 - 0.083 12.1 0.0 0.083 12.1 0.0 2.4 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Dpy19 PF10034.9 KNE02221.1 - 0.11 10.7 0.4 0.13 10.4 0.4 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation DUF3671 PF12420.8 KNE02221.1 - 5.3 7.1 7.5 60 3.7 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function PIP5K PF01504.18 KNE02222.1 - 2.3e-42 145.1 5.6 1.3e-32 113.1 4.0 3.1 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KNE02222.1 - 7.6e-24 84.2 0.0 1.5e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KNE02222.1 - 2.2e-14 53.4 10.8 2.2e-14 53.4 10.8 2.0 2 0 0 2 2 2 1 FYVE zinc finger GPP34 PF05719.11 KNE02225.1 - 2.2e-67 227.0 0.1 2.7e-67 226.7 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Glyco_hydro_18 PF00704.28 KNE02226.1 - 2.9e-66 224.3 5.9 3.4e-66 224.1 5.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Response_reg PF00072.24 KNE02226.1 - 0.015 15.4 0.1 0.38 11.0 0.0 2.3 1 1 1 2 2 2 0 Response regulator receiver domain UCH PF00443.29 KNE02227.1 - 1.7e-42 145.7 0.3 2.8e-42 145.0 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KNE02227.1 - 8.3e-24 83.7 10.9 8.7e-20 70.8 7.7 2.9 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 KNE02227.1 - 4.4e-21 74.4 1.9 1.4e-19 69.6 0.1 2.7 2 0 0 2 2 2 1 Variant UBP zinc finger UBA PF00627.31 KNE02227.1 - 1.3e-20 72.9 0.4 2.2e-09 37.0 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 KNE02227.1 - 5.6e-17 62.3 1.0 1.1e-15 58.0 1.0 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Cytochrome_C7 PF14522.6 KNE02227.1 - 0.059 13.4 0.2 0.059 13.4 0.2 3.2 5 0 0 5 5 5 0 Cytochrome c7 and related cytochrome c DAHP_synth_1 PF00793.20 KNE02229.1 - 6.5e-82 274.5 0.0 7.6e-82 274.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family AA_permease_2 PF13520.6 KNE02230.1 - 7.1e-48 163.5 52.1 8.5e-48 163.2 52.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KNE02230.1 - 6.6e-27 94.2 43.5 8.7e-27 93.8 43.5 1.0 1 0 0 1 1 1 1 Amino acid permease SfLAP PF11139.8 KNE02230.1 - 0.0067 15.9 15.0 0.4 10.1 4.1 3.7 2 2 0 2 2 2 2 Sap, sulfolipid-1-addressing protein GWT1 PF06423.12 KNE02230.1 - 3.4 7.8 7.4 2.5 8.2 4.5 2.3 2 1 0 2 2 2 0 GWT1 DUF2678 PF10856.8 KNE02230.1 - 9.3 6.2 18.7 0.076 13.0 2.1 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF2678) MatE PF01554.18 KNE02231.1 - 2.7e-70 235.2 26.4 1.9e-41 141.4 9.5 2.2 2 0 0 2 2 2 2 MatE Glyco_hydro_76 PF03663.14 KNE02233.1 - 2.3e-139 465.0 16.3 3e-139 464.6 16.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 HAD_2 PF13419.6 KNE02235.1 - 1.2e-10 41.8 0.1 2.1e-10 41.0 0.1 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KNE02235.1 - 1.5e-06 28.2 0.0 4e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KNE02235.1 - 4.9e-06 27.0 0.0 7.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Fungal_trans_2 PF11951.8 KNE02236.1 - 1.1e-43 149.6 1.6 2e-43 148.7 1.6 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNE02236.1 - 6.3e-08 32.6 7.6 2e-07 31.0 7.6 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BDV_P24 PF06595.11 KNE02236.1 - 0.071 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Borna disease virus P24 protein Adap_comp_sub PF00928.21 KNE02237.1 - 3.7e-53 180.6 0.4 5.5e-53 180.0 0.4 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KNE02237.1 - 0.0078 16.2 1.0 0.22 11.5 0.2 2.5 2 0 0 2 2 2 1 Clathrin adaptor complex small chain DUF908 PF06012.12 KNE02237.1 - 2.8 7.3 10.6 2.6 7.4 5.4 2.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF908) Pterin_4a PF01329.19 KNE02238.1 - 3.4e-21 75.2 0.3 5.1e-21 74.6 0.3 1.3 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase DUF1670 PF07900.11 KNE02238.1 - 0.039 13.3 0.6 0.055 12.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1670) GH43_C PF16369.5 KNE02238.1 - 0.081 13.5 0.1 0.12 13.0 0.1 1.3 1 0 0 1 1 1 0 C-terminal lipocalin-like domain HA2 PF04408.23 KNE02240.1 - 1.1e-25 90.0 0.0 1.1e-25 90.0 0.0 3.0 3 1 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KNE02240.1 - 5.4e-11 42.8 0.0 1.2e-09 38.5 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KNE02240.1 - 2.3e-09 37.6 0.3 3.3e-08 33.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain OB_NTP_bind PF07717.16 KNE02240.1 - 9.5e-09 35.5 0.0 3.4e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KNE02240.1 - 2.4e-07 30.7 0.0 6e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 KNE02240.1 - 0.0026 16.8 0.0 0.04 13.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 KNE02240.1 - 0.021 15.2 0.0 0.056 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KNE02240.1 - 0.034 13.5 0.1 0.17 11.2 0.0 2.2 2 0 0 2 2 2 0 KaiC Synaptobrevin PF00957.21 KNE02241.1 - 4.5e-24 84.1 0.3 9e-24 83.1 0.3 1.5 1 0 0 1 1 1 1 Synaptobrevin DUF2207 PF09972.9 KNE02241.1 - 0.0025 16.7 0.0 0.0056 15.5 0.0 1.4 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) FctA PF12892.7 KNE02241.1 - 0.064 14.1 0.1 0.078 13.8 0.1 1.2 1 0 0 1 1 1 0 Spy0128-like isopeptide containing domain Orf78 PF06024.12 KNE02241.1 - 0.8 10.0 3.6 0.56 10.5 1.6 1.8 1 1 1 2 2 2 0 Orf78 (ac78) Histone PF00125.24 KNE02242.1 - 1.3e-08 35.3 0.1 1.3e-08 35.3 0.1 2.4 2 1 0 3 3 3 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KNE02242.1 - 1.7e-07 31.4 0.1 2.8e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KNE02242.1 - 1.8e-07 31.2 0.3 3.8e-07 30.2 0.1 1.5 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold BUD22 PF09073.10 KNE02242.1 - 0.033 13.6 20.0 0.035 13.5 20.0 1.1 1 0 0 1 1 1 0 BUD22 TAFII28 PF04719.14 KNE02242.1 - 0.076 13.1 0.4 0.12 12.5 0.4 1.4 1 0 0 1 1 1 0 hTAFII28-like protein conserved region DUF2540 PF10802.8 KNE02242.1 - 0.2 11.7 0.2 0.2 11.7 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2540) Herpes_UL25 PF01499.16 KNE02242.1 - 0.25 9.8 5.1 0.34 9.4 5.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family MOZ_SAS PF01853.18 KNE02243.1 - 9.4e-47 159.0 0.1 1.4e-46 158.4 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KNE02243.1 - 5.4e-08 32.3 8.8 2.3e-06 27.1 1.2 2.9 3 0 0 3 3 3 2 MYST family zinc finger domain SNF2_N PF00176.23 KNE02244.1 - 3.6e-69 233.1 0.0 5.6e-69 232.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KNE02244.1 - 3.7e-15 56.2 0.0 1.2e-14 54.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.11 KNE02244.1 - 1.2e-12 47.5 0.0 3.4e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 HIRAN domain zf-RING_2 PF13639.6 KNE02244.1 - 1e-08 35.4 9.1 2.5e-08 34.1 9.1 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KNE02244.1 - 1.6e-05 24.7 9.8 3.1e-05 23.7 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KNE02244.1 - 2.4e-05 24.1 5.5 4.1e-05 23.3 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KNE02244.1 - 3.1e-05 23.8 8.7 6.1e-05 22.9 8.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KNE02244.1 - 0.00022 21.2 7.5 0.00046 20.2 7.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KNE02244.1 - 0.0085 15.9 9.1 0.017 14.9 9.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KNE02244.1 - 0.012 15.7 2.3 0.024 14.7 2.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KNE02244.1 - 0.022 15.1 6.1 0.056 13.7 6.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KNE02244.1 - 0.028 14.6 9.0 0.072 13.3 9.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf_Rg PF17915.1 KNE02244.1 - 0.066 12.6 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Reverse gyrase zinc finger VHS PF00790.19 KNE02244.1 - 0.12 12.2 0.6 0.53 10.1 0.0 2.3 3 0 0 3 3 3 0 VHS domain zf-RING_11 PF17123.5 KNE02244.1 - 0.15 11.8 7.6 0.37 10.6 7.6 1.7 1 0 0 1 1 1 0 RING-like zinc finger IBR PF01485.21 KNE02244.1 - 0.2 11.9 6.8 0.088 13.0 4.0 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Prok-RING_4 PF14447.6 KNE02244.1 - 0.23 11.4 6.7 0.43 10.5 6.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KNE02244.1 - 0.33 10.8 5.5 0.73 9.7 5.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Nramp PF01566.18 KNE02246.1 - 2.3e-91 306.4 16.1 8.2e-53 179.6 4.9 2.2 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein Nfu_N PF08712.11 KNE02249.1 - 3.9e-28 97.3 0.1 1e-27 96.0 0.1 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KNE02249.1 - 2e-25 88.7 0.1 3.5e-25 87.9 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain PHO4 PF01384.20 KNE02251.1 - 1e-114 383.1 21.1 1.2e-114 382.9 21.1 1.0 1 0 0 1 1 1 1 Phosphate transporter family F_actin_cap_B PF01115.17 KNE02252.1 - 1.9e-90 302.7 0.2 2.2e-90 302.5 0.2 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Type_III_YscX PF09474.10 KNE02252.1 - 0.084 13.2 1.0 1.7 9.0 0.0 2.3 2 0 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) TDA11 PF17084.5 KNE02253.1 - 1.4e-07 30.9 8.4 1.4e-07 30.9 8.4 2.0 1 1 1 2 2 2 1 Topoisomerase I damage affected protein 11 TolA_bind_tri PF16331.5 KNE02253.1 - 2.5 8.2 12.1 2.7 8.1 5.0 2.6 2 0 0 2 2 2 0 TolA binding protein trimerisation SKA1 PF07160.12 KNE02253.1 - 2.7 7.8 13.1 0.077 12.8 3.6 2.3 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Fib_alpha PF08702.10 KNE02253.1 - 8.6 6.5 10.6 13 6.0 7.9 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TetR_C_28 PF17937.1 KNE02254.1 - 0.17 12.3 0.0 0.32 11.5 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Clathrin_lg_ch PF01086.17 KNE02255.1 - 2.9e-54 184.6 20.7 3.3e-54 184.4 20.7 1.0 1 0 0 1 1 1 1 Clathrin light chain DUF3600 PF12207.8 KNE02255.1 - 0.011 15.6 0.5 0.011 15.6 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3600) DUF3541 PF12060.8 KNE02255.1 - 0.084 12.5 2.9 0.068 12.9 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) MHC_I PF00129.18 KNE02255.1 - 0.11 12.1 1.9 0.18 11.3 1.9 1.4 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 MRP-S26 PF14943.6 KNE02255.1 - 0.12 12.3 12.3 0.16 11.9 12.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF2564 PF10819.8 KNE02255.1 - 1.6 9.2 8.5 0.58 10.6 1.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2564) WD40 PF00400.32 KNE02256.1 - 3.9e-31 106.6 13.9 9.7e-05 23.1 0.0 10.6 12 0 0 12 12 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNE02256.1 - 7e-10 39.1 5.6 0.94 9.8 0.0 7.2 5 2 4 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KNE02256.1 - 0.00047 19.2 0.5 0.11 11.5 0.1 4.0 4 1 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Med20 PF08612.11 KNE02257.1 - 6.2e-22 78.1 0.0 6.8e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DEAD PF00270.29 KNE02258.1 - 3.8e-47 160.3 0.2 1.3e-46 158.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNE02258.1 - 1.6e-21 76.7 0.0 9e-21 74.3 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KNE02258.1 - 4.4e-19 68.5 0.0 1.3e-18 66.9 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KNE02258.1 - 6.4e-06 26.3 0.0 6.4e-06 26.3 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit A_deaminase_N PF08451.11 KNE02258.1 - 0.0027 18.0 0.3 0.0099 16.2 0.3 2.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal Helicase_C_2 PF13307.6 KNE02258.1 - 0.081 13.1 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Helicase C-terminal domain RNA_pol_Rpc4 PF05132.14 KNE02259.1 - 2.3e-17 63.8 0.0 2.3e-17 63.8 0.0 2.9 3 1 0 3 3 3 1 RNA polymerase III RPC4 Peptidase_U49 PF10463.9 KNE02259.1 - 0.03 14.1 0.1 0.056 13.2 0.1 1.4 1 0 0 1 1 1 0 Peptidase U49 Sas10 PF09368.10 KNE02260.1 - 3e-26 91.7 12.1 3e-26 91.7 12.1 2.4 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KNE02260.1 - 1.1e-05 26.0 0.0 1.1e-05 26.0 0.0 2.7 3 0 0 3 3 3 1 Sas10/Utp3/C1D family Cpn60_TCP1 PF00118.24 KNE02261.1 - 8e-151 503.0 12.2 9e-151 502.8 12.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AbrB_C PF18277.1 KNE02261.1 - 0.0072 15.9 0.3 0.32 10.7 0.1 3.0 2 1 1 3 3 3 1 AbrB C-terminal domain D123 PF07065.14 KNE02262.1 - 2.3e-90 302.9 0.6 2.7e-90 302.7 0.6 1.0 1 0 0 1 1 1 1 D123 SGL PF08450.12 KNE02263.1 - 1.4e-29 103.4 0.0 1.6e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KNE02263.1 - 0.00024 21.2 0.0 0.0047 17.0 0.0 2.5 2 0 0 2 2 2 1 Strictosidine synthase Hit1_C PF18268.1 KNE02264.1 - 5.4e-08 32.9 0.2 1.2e-07 31.8 0.0 1.7 1 1 1 2 2 2 1 Hit1 C-terminal zf-HIT PF04438.16 KNE02264.1 - 6.3e-08 32.3 10.6 6.3e-08 32.3 10.6 1.7 2 0 0 2 2 2 1 HIT zinc finger zf-MYND PF01753.18 KNE02264.1 - 0.0012 18.9 8.3 0.002 18.2 8.3 1.3 1 0 0 1 1 1 1 MYND finger YfkD PF14167.6 KNE02264.1 - 0.055 12.6 1.0 0.071 12.3 1.0 1.1 1 0 0 1 1 1 0 YfkD-like protein zf-C6H2 PF15801.5 KNE02264.1 - 0.15 12.4 6.9 0.4 11.0 6.9 1.7 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Cyclin_N PF00134.23 KNE02266.1 - 0.00024 20.9 0.2 0.0004 20.1 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Fungal_trans PF04082.18 KNE02271.1 - 3.5e-16 59.0 2.4 7.2e-16 58.0 2.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNE02271.1 - 2.4e-09 37.1 11.4 4.3e-09 36.3 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gemini_C4 PF01492.17 KNE02271.1 - 0.038 13.9 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 Geminivirus C4 protein Cas6b_C PF17262.2 KNE02271.1 - 0.079 13.1 0.0 3 8.0 0.0 2.7 2 0 0 2 2 2 0 Cas6b C-terminal domain zf-C2H2 PF00096.26 KNE02273.1 - 6.9e-09 35.7 15.4 0.00015 22.0 2.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KNE02273.1 - 3.5e-07 30.4 18.1 0.00012 22.4 4.5 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KNE02273.1 - 8e-05 23.2 11.7 0.028 15.2 1.0 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KNE02273.1 - 0.05 13.6 1.1 4.4 7.4 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KNE02273.1 - 0.15 12.4 2.1 0.48 10.8 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KNE02273.1 - 0.25 12.0 1.9 0.27 11.9 0.1 2.0 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 KNE02273.1 - 5.6 6.8 14.3 1.2 9.0 0.3 3.7 4 0 0 4 4 4 0 C2H2-type zinc-finger domain DUF1840 PF08895.11 KNE02274.1 - 0.018 15.4 0.3 0.019 15.3 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DUF5480 PF17576.2 KNE02274.1 - 0.1 12.5 0.2 0.17 11.8 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5480) Cyclin_N PF00134.23 KNE02277.1 - 0.021 14.6 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain CHZ PF09649.10 KNE02278.1 - 1e-18 66.5 1.4 1e-18 66.5 1.4 2.0 2 0 0 2 2 2 1 Histone chaperone domain CHZ LSM PF01423.22 KNE02279.1 - 6.3e-18 64.2 0.3 9.2e-18 63.7 0.3 1.2 1 0 0 1 1 1 1 LSM domain Ras PF00071.22 KNE02280.1 - 8.8e-59 197.7 0.1 1e-58 197.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNE02280.1 - 1.1e-34 119.2 0.0 1.6e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNE02280.1 - 2.8e-12 46.4 0.0 3.7e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KNE02280.1 - 3.8e-07 30.2 0.0 5.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase KAP_NTPase PF07693.14 KNE02280.1 - 0.0022 17.3 0.0 0.0037 16.5 0.0 1.3 1 1 0 1 1 1 1 KAP family P-loop domain GTP_EFTU PF00009.27 KNE02280.1 - 0.0024 17.4 0.0 0.0065 16.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KNE02280.1 - 0.0027 17.6 0.6 0.026 14.4 0.1 2.1 1 1 1 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KNE02280.1 - 0.0046 17.2 0.1 0.11 12.8 0.0 2.1 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KNE02280.1 - 0.0077 16.6 0.1 0.015 15.7 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KNE02280.1 - 0.016 15.7 0.0 0.02 15.4 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KNE02280.1 - 0.019 14.7 0.0 0.038 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 KNE02280.1 - 0.045 13.2 0.0 0.094 12.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KNE02280.1 - 0.062 13.1 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KNE02280.1 - 0.084 12.8 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 NTPase FeoB_N PF02421.18 KNE02280.1 - 0.12 11.8 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 KNE02280.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 KNE02280.1 - 0.18 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FACT-Spt16_Nlob PF14826.6 KNE02281.1 - 2.4e-51 173.8 3.6 2.6e-50 170.4 3.3 2.5 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.11 KNE02281.1 - 2.8e-48 163.9 0.2 2.8e-48 163.9 0.2 2.6 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 KNE02281.1 - 6.7e-24 84.8 0.0 1.1e-23 84.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KNE02281.1 - 2.3e-14 53.5 1.9 1.3e-13 51.1 0.1 2.8 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Creatinase_N PF01321.18 KNE02281.1 - 0.019 15.6 0.1 0.16 12.6 0.0 2.4 2 0 0 2 2 2 0 Creatinase/Prolidase N-terminal domain DNA_primase_lrg PF04104.14 KNE02283.1 - 3.8e-78 262.6 0.0 5.6e-78 262.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DpnI_C PF17726.1 KNE02283.1 - 0.18 12.0 5.6 1.9 8.7 0.8 3.2 3 0 0 3 3 3 0 Dam-replacing HTH domain PEX11 PF05648.14 KNE02284.1 - 0.014 14.9 5.4 0.88 9.0 0.2 3.1 1 1 1 3 3 3 0 Peroxisomal biogenesis factor 11 (PEX11) 2TM PF13239.6 KNE02284.1 - 1.6 9.1 5.7 0.41 11.0 2.3 1.8 1 1 0 1 1 1 0 2TM domain Xan_ur_permease PF00860.20 KNE02285.1 - 2.9e-68 230.3 30.3 4.3e-68 229.8 30.3 1.2 1 0 0 1 1 1 1 Permease family LicD PF04991.13 KNE02289.1 - 4.2e-32 112.1 12.7 1.1e-27 97.7 0.9 3.8 2 1 1 3 3 3 2 LicD family HLH PF00010.26 KNE02290.1 - 4.6e-14 52.1 2.4 4.6e-14 52.1 2.4 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain TFIIA PF03153.13 KNE02290.1 - 0.01 15.9 17.8 0.013 15.6 17.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 KNE02290.1 - 0.26 10.9 12.4 0.41 10.2 12.4 1.4 1 0 0 1 1 1 0 Spt20 family VPS13_mid_rpt PF16910.5 KNE02290.1 - 0.32 10.4 7.2 0.22 10.9 2.2 2.1 2 0 0 2 2 2 0 Repeating coiled region of VPS13 DUF2229 PF09989.9 KNE02290.1 - 0.89 9.2 9.1 3.7 7.1 0.7 2.2 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) SUIM_assoc PF16619.5 KNE02290.1 - 1.5 8.9 17.3 2.2 8.4 15.9 1.9 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF3450 PF11932.8 KNE02290.1 - 2.7 7.2 22.4 0.21 10.8 4.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DivIC PF04977.15 KNE02290.1 - 4.5 7.1 13.6 2.6 7.9 2.3 2.8 2 1 0 2 2 2 0 Septum formation initiator TPP_enzyme_N PF02776.18 KNE02291.1 - 4.1e-31 107.9 0.0 7e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KNE02291.1 - 9.6e-29 99.9 0.0 6.5e-28 97.2 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KNE02291.1 - 4e-12 46.2 0.0 8.1e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain OCC1 PF15506.6 KNE02291.1 - 0.17 12.0 0.4 19 5.5 0.1 2.5 2 0 0 2 2 2 0 OCC1 family ABC_membrane PF00664.23 KNE02292.1 - 6.5e-44 150.6 16.2 8.7e-44 150.2 16.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KNE02292.1 - 3.2e-34 118.4 0.0 6.6e-34 117.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KNE02292.1 - 3.2e-08 33.3 0.0 0.00011 21.7 0.0 2.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KNE02292.1 - 0.00065 20.0 0.0 0.007 16.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KNE02292.1 - 0.0034 17.1 0.1 0.0089 15.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KNE02292.1 - 0.005 17.2 0.1 0.013 15.9 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KNE02292.1 - 0.0067 16.3 0.1 0.025 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 KNE02292.1 - 0.016 15.0 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 KNE02292.1 - 0.075 11.9 0.0 0.25 10.2 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain Cytidylate_kin PF02224.18 KNE02292.1 - 0.085 12.6 1.9 0.28 10.9 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase AAA_30 PF13604.6 KNE02292.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KNE02292.1 - 0.12 12.0 0.0 0.6 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 KNE02292.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Peptidase_M1 PF01433.20 KNE02295.1 - 7e-38 130.4 0.1 1.7e-37 129.2 0.1 1.7 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KNE02295.1 - 4.5e-36 125.0 2.2 6.2e-36 124.5 2.2 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KNE02295.1 - 6e-30 104.8 2.0 6e-30 104.8 2.0 1.9 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Post_transc_reg PF13797.6 KNE02295.1 - 2 8.3 5.4 0.95 9.4 2.1 2.2 2 0 0 2 2 2 0 Post-transcriptional regulator BCL9 PF11502.8 KNE02296.1 - 0.029 14.2 0.3 0.035 13.9 0.3 1.2 1 0 0 1 1 1 0 B-cell lymphoma 9 protein DUF5437 PF17505.2 KNE02298.1 - 0.12 12.4 0.6 0.2 11.7 0.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5437) PseudoU_synth_1 PF01416.20 KNE02301.1 - 6.5e-14 52.3 0.0 1.8e-10 41.3 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase UPF0113_N PF17833.1 KNE02303.1 - 4.3e-31 107.3 0.1 6.9e-31 106.6 0.1 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KNE02303.1 - 3.2e-24 85.0 0.0 6.9e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 UPF0113 PUA domain Sortase PF04203.13 KNE02303.1 - 0.11 12.3 0.1 0.42 10.4 0.0 1.9 1 1 1 2 2 2 0 Sortase domain DAP3 PF10236.9 KNE02304.1 - 2.4e-58 197.8 0.0 3.1e-58 197.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 RsgA_GTPase PF03193.16 KNE02304.1 - 0.023 14.6 0.0 0.058 13.3 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KNE02304.1 - 0.038 13.8 0.0 0.092 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KNE02304.1 - 0.056 13.8 0.1 0.25 11.7 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain Tox-MPTase2 PF15638.6 KNE02304.1 - 0.09 12.5 0.6 0.19 11.5 0.6 1.5 1 0 0 1 1 1 0 Metallopeptidase toxin 2 ABC_tran PF00005.27 KNE02304.1 - 0.093 13.2 0.1 0.29 11.6 0.0 2.0 2 0 0 2 2 2 0 ABC transporter DEAD PF00270.29 KNE02305.1 - 5.1e-22 78.5 0.0 3.5e-21 75.7 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNE02305.1 - 5.4e-17 62.1 0.0 4e-16 59.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNE02305.1 - 8.3e-08 32.4 0.0 1.6e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KNE02305.1 - 0.17 12.1 0.1 17 5.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain ETRAMP PF09716.10 KNE02306.1 - 1.2 9.2 8.9 1.2 9.2 8.9 1.1 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) NUDIX PF00293.28 KNE02307.1 - 7.3e-13 48.7 0.0 1.4e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 KNE02307.1 - 3.4e-05 23.4 0.5 6.6e-05 22.5 0.5 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NUDIX-like PF09296.11 KNE02307.1 - 0.00031 21.4 0.0 0.00064 20.3 0.0 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain DZR PF12773.7 KNE02307.1 - 0.13 12.4 0.2 0.25 11.4 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon Nudix_N_2 PF14803.6 KNE02307.1 - 0.52 10.3 3.4 16 5.5 3.4 2.6 1 1 0 1 1 1 0 Nudix N-terminal GDPD PF03009.17 KNE02308.1 - 1.1e-23 84.3 0.1 8.2e-23 81.4 0.1 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF3696 PF12476.8 KNE02308.1 - 0.0087 16.4 0.1 0.23 11.9 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3696) L_lactis_ph-MCP PF06673.11 KNE02308.1 - 0.041 12.9 0.1 0.06 12.3 0.1 1.1 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein SKIP_SNW PF02731.15 KNE02309.1 - 3e-40 137.5 7.5 4.7e-40 136.9 7.5 1.3 1 0 0 1 1 1 1 SKIP/SNW domain WAC_Acf1_DNA_bd PF10537.9 KNE02310.1 - 1.9e-36 124.6 1.4 1.9e-36 124.6 1.4 2.4 3 0 0 3 3 3 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KNE02310.1 - 5e-17 62.2 1.4 5e-17 62.2 1.4 3.7 4 1 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KNE02310.1 - 7.6e-13 48.6 0.9 2.9e-12 46.7 1.2 1.9 2 0 0 2 2 2 1 DDT domain WHIM1 PF15612.6 KNE02310.1 - 0.0006 19.3 0.0 0.0017 17.9 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 ADH_N PF08240.12 KNE02312.1 - 8.5e-22 77.1 5.9 1.3e-21 76.5 5.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KNE02312.1 - 1.3e-19 70.4 0.0 2.5e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KNE02312.1 - 7.2e-07 30.3 0.0 1.3e-06 29.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KNE02312.1 - 3.3e-05 23.3 0.0 6.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KNE02312.1 - 0.00012 21.4 0.1 0.00028 20.2 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Ubiq_cyt_C_chap PF03981.12 KNE02313.1 - 5.1e-40 136.8 0.4 2e-39 134.9 0.2 1.9 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone Acetyltransf_9 PF13527.7 KNE02314.1 - 0.0085 16.2 0.0 0.36 10.9 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KNE02314.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 KNE02316.1 - 7.2e-12 44.9 23.2 7.2e-12 44.9 23.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily SRP_TPR_like PF17004.5 KNE02317.1 - 5.9e-10 39.2 5.2 2.9e-08 33.7 2.6 3.0 3 0 0 3 3 3 1 Putative TPR-like repeat TPR_12 PF13424.6 KNE02317.1 - 6.9e-06 26.3 8.1 0.094 13.0 0.4 4.6 3 2 0 3 3 3 2 Tetratricopeptide repeat SRP72 PF08492.12 KNE02317.1 - 3.1e-05 24.3 13.3 3.1e-05 24.3 13.3 3.0 2 1 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.6 KNE02317.1 - 3.6e-05 24.2 4.8 0.42 11.1 0.5 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KNE02317.1 - 5.8e-05 23.6 2.8 5.8 8.0 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KNE02317.1 - 0.00014 21.6 3.8 5.8 6.9 0.1 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KNE02317.1 - 0.00034 20.5 9.7 1.9 8.8 0.1 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KNE02317.1 - 0.002 17.9 9.3 1.8 8.5 0.5 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KNE02317.1 - 0.0054 16.9 13.0 2.1 8.8 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KNE02317.1 - 0.032 14.8 1.1 1e+02 3.9 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KNE02317.1 - 0.041 14.5 0.9 30 5.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 KNE02317.1 - 0.083 12.6 0.7 2.1 8.0 0.3 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_5 PF12688.7 KNE02317.1 - 0.088 13.1 0.6 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 Tetratrico peptide repeat GCV_T PF01571.21 KNE02319.1 - 2.1e-83 279.6 0.0 2.5e-83 279.4 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KNE02319.1 - 2.7e-15 56.0 0.0 5.4e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 KNE02319.1 - 0.0065 16.6 0.0 0.19 11.9 0.0 2.3 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family PI3_PI4_kinase PF00454.27 KNE02321.1 - 1.5e-54 185.4 0.0 3.6e-54 184.2 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 KNE02321.1 - 7.9e-16 58.5 4.7 7.7e-15 55.3 2.2 4.0 4 0 0 4 4 4 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 KNE02321.1 - 9.7e-13 47.7 0.0 2.2e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 FATC domain CCDC-167 PF15188.6 KNE02321.1 - 0.083 13.2 0.4 0.29 11.5 0.4 2.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 RRM_1 PF00076.22 KNE02323.1 - 3.1e-23 81.4 3.6 7.1e-07 29.0 1.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KNE02323.1 - 8.6e-09 35.1 0.2 0.27 11.1 0.0 4.3 4 0 0 4 4 4 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KNE02323.1 - 0.065 13.3 0.3 3.8 7.6 0.2 3.3 3 1 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Use1 PF09753.9 KNE02324.1 - 2e-11 44.1 0.2 2.6e-11 43.7 0.2 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 Ribosomal_L14 PF00238.19 KNE02329.1 - 1.5e-22 80.0 0.0 1.6e-22 79.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PH PF00169.29 KNE02330.1 - 1e-08 35.6 0.9 2.4e-08 34.4 0.9 1.7 1 0 0 1 1 1 1 PH domain FliE PF02049.18 KNE02330.1 - 0.18 12.0 3.8 0.21 11.8 1.9 2.2 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE DUF1586 PF07625.11 KNE02331.1 - 0.028 14.5 0.2 0.049 13.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1586) zf-RING_UBOX PF13445.6 KNE02332.1 - 7.8e-10 38.6 2.8 8.5e-10 38.5 1.3 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KNE02332.1 - 2.4e-09 37.4 4.1 3.7e-09 36.8 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KNE02332.1 - 2.5e-09 36.8 5.9 3.1e-09 36.5 3.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KNE02332.1 - 9.6e-09 35.0 4.3 1.8e-08 34.1 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KNE02332.1 - 2.2e-07 30.9 4.4 6.5e-07 29.4 4.5 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KNE02332.1 - 5.1e-07 29.5 7.5 1.9e-06 27.6 7.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KNE02332.1 - 6.2e-06 26.1 8.5 1.5e-05 24.9 8.5 1.7 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KNE02332.1 - 8.1e-05 22.4 8.1 0.0039 17.0 8.6 2.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KNE02332.1 - 0.016 15.2 4.2 0.093 12.8 4.2 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Di19 PF05605.12 KNE02332.1 - 0.017 15.4 6.0 3 8.2 0.9 3.2 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.6 KNE02332.1 - 0.045 13.6 6.4 0.3 10.9 6.4 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain FYVE PF01363.21 KNE02332.1 - 0.051 13.7 5.7 0.11 12.6 5.7 1.6 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_11 PF17123.5 KNE02332.1 - 0.086 12.6 5.5 0.22 11.3 5.5 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 KNE02332.1 - 0.11 12.7 8.1 0.44 10.9 8.1 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain TerY_C PF15616.6 KNE02332.1 - 0.14 12.3 7.2 2.7 8.1 3.6 2.2 1 1 1 2 2 2 0 TerY-C metal binding domain FANCL_C PF11793.8 KNE02332.1 - 0.21 11.8 4.0 0.8 9.9 4.0 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C6H2 PF15801.5 KNE02332.1 - 2.2 8.6 7.2 18 5.7 4.0 2.9 2 1 1 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding zf-MIZ PF02891.20 KNE02332.1 - 5.9 6.7 7.4 22 4.9 7.4 2.0 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Bax1-I PF01027.20 KNE02334.1 - 2e-52 178.0 24.6 2.3e-52 177.8 24.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 AAA PF00004.29 KNE02336.1 - 6.4e-40 136.6 0.0 1e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KNE02336.1 - 4.9e-11 42.2 0.4 9.4e-11 41.3 0.4 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KNE02336.1 - 4.9e-10 39.2 0.1 1e-09 38.2 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 KNE02336.1 - 5.9e-06 26.6 0.2 0.011 16.0 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.14 KNE02336.1 - 2.1e-05 24.7 0.0 7.9e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KNE02336.1 - 3.5e-05 23.1 0.0 5.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KNE02336.1 - 0.00013 22.0 0.1 0.00075 19.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KNE02336.1 - 0.00041 20.8 0.2 0.0017 18.8 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KNE02336.1 - 0.00049 19.9 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KNE02336.1 - 0.0023 18.2 0.2 0.0056 16.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KNE02336.1 - 0.0073 16.2 0.0 0.019 14.8 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KNE02336.1 - 0.01 15.2 0.1 0.32 10.3 0.1 2.2 1 1 1 2 2 2 0 KaiC AAA_33 PF13671.6 KNE02336.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KNE02336.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 KNE02336.1 - 0.018 14.2 1.2 0.04 13.1 0.1 2.0 2 1 0 2 2 2 0 TIP49 P-loop domain AAA_18 PF13238.6 KNE02336.1 - 0.022 15.3 0.1 0.047 14.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 KNE02336.1 - 0.025 14.6 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 KNE02336.1 - 0.032 13.9 0.0 0.11 12.1 0.0 2.0 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain RNA_helicase PF00910.22 KNE02336.1 - 0.037 14.4 0.0 0.072 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KNE02336.1 - 0.039 13.3 0.1 0.081 12.3 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 KNE02336.1 - 0.046 13.6 0.4 0.51 10.2 0.0 2.6 3 0 0 3 3 3 0 NTPase Zeta_toxin PF06414.12 KNE02336.1 - 0.072 12.4 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 KNE02336.1 - 0.076 12.6 0.0 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KNE02336.1 - 0.079 12.4 1.0 0.33 10.4 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 KNE02336.1 - 0.11 12.2 1.7 0.25 11.0 0.1 2.2 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 KNE02336.1 - 0.13 12.2 0.3 0.45 10.4 0.1 1.9 2 0 0 2 2 2 0 NACHT domain CPT PF07931.12 KNE02336.1 - 0.15 11.9 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF2075 PF09848.9 KNE02336.1 - 0.17 11.1 0.1 0.24 10.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KNE02336.1 - 0.18 11.3 0.0 0.46 10.0 0.0 1.6 2 0 0 2 2 1 0 P-loop containing dynein motor region Thioredoxin PF00085.20 KNE02337.1 - 1.1e-28 99.2 0.1 1.3e-28 99.0 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KNE02337.1 - 1.2e-05 24.9 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 KNE02337.1 - 3e-05 23.8 0.0 3.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KNE02337.1 - 7e-05 23.2 0.1 0.00028 21.3 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KNE02337.1 - 0.00047 20.3 0.0 0.00077 19.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KNE02337.1 - 0.0031 17.4 0.1 0.0087 16.0 0.0 1.6 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KNE02337.1 - 0.011 16.0 0.0 0.02 15.2 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 KNE02337.1 - 0.014 15.2 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Redoxin Phosducin PF02114.16 KNE02337.1 - 0.02 13.9 0.0 0.02 13.8 0.0 1.0 1 0 0 1 1 1 0 Phosducin CPL PF08144.11 KNE02338.1 - 2.3e-38 131.8 9.3 3.4e-36 124.7 0.5 5.2 4 1 2 6 6 6 1 CPL (NUC119) domain PUF PF00806.19 KNE02338.1 - 2.8e-08 33.0 0.7 0.18 11.6 0.0 4.6 4 0 0 4 4 4 3 Pumilio-family RNA binding repeat SAC3 PF12209.8 KNE02338.1 - 0.41 10.9 2.9 32 4.8 0.0 4.2 4 1 1 5 5 5 0 Leucine permease transcriptional regulator helical domain Drc1-Sld2 PF11719.8 KNE02338.1 - 0.65 9.5 17.9 1.4 8.3 17.9 1.6 1 0 0 1 1 1 0 DNA replication and checkpoint protein SDA1 PF05285.12 KNE02338.1 - 1.4 8.3 33.3 2.9 7.2 33.3 1.5 1 0 0 1 1 1 0 SDA1 NDUFA12 PF05071.16 KNE02339.1 - 3.7e-10 40.5 5.1 9.8e-10 39.1 4.9 1.9 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 SNAD3 PF18749.1 KNE02339.1 - 0.044 12.9 2.1 0.063 12.4 2.1 1.1 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 3 Fungal_TACC PF12709.7 KNE02339.1 - 0.057 13.9 8.5 0.44 11.0 2.4 2.4 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Prominin PF05478.11 KNE02339.1 - 0.15 10.0 2.0 0.18 9.8 2.0 1.0 1 0 0 1 1 1 0 Prominin PRKG1_interact PF15898.5 KNE02339.1 - 1.9 9.4 12.3 0.99 10.3 4.8 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain YabA PF06156.13 KNE02339.1 - 3 8.5 7.7 13 6.5 7.7 2.0 1 1 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 KNE02339.1 - 5 7.0 12.5 2.7 7.8 7.9 2.2 1 1 1 2 2 2 0 Septum formation initiator PX PF00787.24 KNE02340.1 - 4e-16 59.0 0.0 5.1e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 PX domain Pyr_redox_2 PF07992.14 KNE02342.1 - 1.1e-52 179.1 0.2 1.3e-52 178.9 0.2 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KNE02342.1 - 2.4e-18 66.5 0.3 1e-15 58.1 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KNE02342.1 - 1.3e-17 64.0 0.0 4e-16 59.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KNE02342.1 - 0.00023 20.4 1.7 2.8 6.9 0.1 3.6 3 1 1 4 4 4 3 Glucose inhibited division protein A K_oxygenase PF13434.6 KNE02342.1 - 0.00031 20.0 0.0 0.63 9.1 0.0 3.2 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 KNE02342.1 - 0.0011 19.3 0.0 0.61 10.6 0.0 2.5 2 1 0 2 2 2 2 Putative NAD(P)-binding Thi4 PF01946.17 KNE02342.1 - 0.003 16.8 0.1 0.012 14.8 0.0 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KNE02342.1 - 0.0039 17.4 0.0 0.045 14.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KNE02342.1 - 0.084 12.9 0.6 8.6 6.4 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase SNARE PF05739.19 KNE02343.1 - 3.4e-11 43.0 0.2 3.4e-11 43.0 0.2 2.5 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.6 KNE02343.1 - 3.7e-07 30.4 6.7 3.7e-07 30.4 6.7 2.7 3 0 0 3 3 3 2 Syntaxin-like protein KIP1 PF07765.12 KNE02343.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.7 2 1 1 3 3 3 0 KIP1-like protein DUF4407 PF14362.6 KNE02343.1 - 0.24 10.7 6.2 0.32 10.3 6.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MCPsignal PF00015.21 KNE02343.1 - 0.41 10.4 6.8 0.57 10.0 4.3 2.2 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain RICH PF05062.12 KNE02343.1 - 2.1 8.7 11.2 3.5 8.0 1.1 3.5 3 1 0 3 3 3 0 RICH domain DUF1664 PF07889.12 KNE02343.1 - 2.5 8.1 11.2 1.1 9.3 5.3 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) SKA1 PF07160.12 KNE02343.1 - 3.3 7.5 17.9 3.4 7.4 1.0 3.0 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 WD40 PF00400.32 KNE02344.1 - 1.3e-32 111.3 18.1 3.1e-07 31.0 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNE02344.1 - 1.4e-11 44.5 2.5 0.035 14.4 0.1 4.9 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KNE02344.1 - 0.066 13.2 0.0 12 6.0 0.0 3.8 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Hira PF07569.11 KNE02345.1 - 9e-79 264.3 0.9 1.6e-77 260.2 0.0 2.8 3 0 0 3 3 3 1 TUP1-like enhancer of split HIRA_B PF09453.10 KNE02345.1 - 5.4e-10 38.9 1.3 1.5e-09 37.5 1.3 1.8 1 0 0 1 1 1 1 HIRA B motif ANAPC4_WD40 PF12894.7 KNE02345.1 - 3.4e-08 33.7 0.5 0.00041 20.6 0.1 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KNE02345.1 - 9.6e-06 26.3 19.2 0.83 10.6 0.2 6.6 7 1 0 7 7 7 3 WD domain, G-beta repeat WD40_like PF17005.5 KNE02345.1 - 0.0002 20.8 0.6 4.4 6.5 0.3 4.5 5 0 0 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 KNE02345.1 - 0.00083 18.4 0.3 3.3 6.6 0.0 4.2 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KNE02345.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal CK_II_beta PF01214.18 KNE02346.1 - 2.7e-73 245.7 0.0 3.3e-73 245.4 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit VHP PF02209.19 KNE02346.1 - 0.068 13.3 0.8 0.13 12.3 0.8 1.4 1 0 0 1 1 1 0 Villin headpiece domain tRNA-synt_1b PF00579.25 KNE02348.1 - 1.1e-67 228.4 0.0 1.5e-67 228.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) NCD1 PF04904.13 KNE02348.1 - 0.053 13.5 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) GATA PF00320.27 KNE02349.1 - 0.16 11.6 1.6 0.43 10.2 0.2 2.2 2 0 0 2 2 2 0 GATA zinc finger PNP_UDP_1 PF01048.20 KNE02350.1 - 1.9e-53 181.1 0.0 2.4e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily WD40 PF00400.32 KNE02351.1 - 4.1e-16 59.1 21.9 0.00041 21.1 0.3 6.8 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNE02351.1 - 1.1e-09 38.4 1.5 0.059 13.7 0.1 3.7 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain DUF3915 PF13054.6 KNE02351.1 - 0.13 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) NYD-SP28 PF14772.6 KNE02352.1 - 0.0059 16.6 5.2 0.28 11.2 0.3 2.6 2 1 0 2 2 2 2 Sperm tail Phage_TAC_4 PF08748.11 KNE02352.1 - 1.5 9.2 5.8 0.56 10.5 0.3 2.1 1 1 1 2 2 2 0 Phage tail assembly chaperone Hemerythrin PF01814.23 KNE02353.1 - 0.08 13.6 0.4 0.21 12.2 0.4 1.7 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain HSBP1 PF06825.12 KNE02353.1 - 7.9 6.4 6.9 5.2 7.0 0.8 3.3 3 1 0 3 3 3 0 Heat shock factor binding protein 1 Ras PF00071.22 KNE02354.1 - 5.5e-24 84.6 0.0 8.4e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Ras family Resolvase PF00239.21 KNE02356.1 - 0.068 13.3 0.0 0.072 13.2 0.0 1.1 1 0 0 1 1 1 0 Resolvase, N terminal domain GST_N_2 PF13409.6 KNE02357.1 - 3.3e-23 81.7 0.1 2e-22 79.2 0.0 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KNE02357.1 - 9.7e-13 47.9 0.0 2.1e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KNE02357.1 - 1.2e-05 25.6 0.0 0.081 13.3 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KNE02357.1 - 1.8e-05 24.9 0.1 4.4e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KNE02357.1 - 0.00093 19.4 0.1 0.0019 18.3 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain BORCS6 PF10157.9 KNE02357.1 - 0.096 12.9 0.1 0.15 12.3 0.1 1.2 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 DUF3189 PF11385.8 KNE02357.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3189) zf-C2H2 PF00096.26 KNE02359.1 - 4.6e-05 23.6 16.4 0.00023 21.5 0.5 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KNE02359.1 - 0.0072 17.1 20.9 0.012 16.4 0.6 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KNE02359.1 - 0.56 10.7 8.6 4.3 7.9 3.9 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KNE02359.1 - 0.81 10.0 13.7 6.4 7.2 0.4 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding MCM PF00493.23 KNE02360.1 - 2.1e-101 337.7 0.4 2.9e-101 337.2 0.4 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KNE02360.1 - 8.8e-38 129.0 0.1 1.9e-37 127.9 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KNE02360.1 - 2.1e-32 111.5 1.2 4.6e-32 110.5 1.2 1.6 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 KNE02360.1 - 3e-25 88.5 2.7 3.2e-25 88.4 0.7 2.1 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KNE02360.1 - 8.3e-22 77.7 0.0 2.9e-21 76.0 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KNE02360.1 - 4.4e-06 26.2 0.0 2.9e-05 23.6 0.0 2.0 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KNE02360.1 - 0.0091 15.9 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KNE02360.1 - 0.013 15.2 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain BBP1_N PF15271.6 KNE02360.1 - 0.095 13.5 0.2 0.22 12.3 0.2 1.6 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein AhpC-TSA PF00578.21 KNE02362.1 - 1.2e-32 112.4 0.0 1.7e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 KNE02362.1 - 6.2e-13 48.4 0.1 1.1e-12 47.6 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 KNE02362.1 - 1.3e-12 47.7 0.0 1.8e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin Fungal_trans PF04082.18 KNE02363.1 - 6.6e-16 58.1 1.0 1.4e-15 57.1 1.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNE02363.1 - 7.2e-08 32.4 8.7 1.1e-07 31.8 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rad51 PF08423.11 KNE02365.1 - 8.8e-132 438.0 0.0 1e-131 437.8 0.0 1.0 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KNE02365.1 - 1.2e-10 41.3 0.0 1.7e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 KNE02365.1 - 1.9e-08 34.1 0.0 2.7e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 KNE02365.1 - 1.8e-06 28.4 0.4 4.2e-06 27.3 0.4 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 KNE02365.1 - 2.9e-05 23.5 0.9 0.00015 21.2 0.9 2.0 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 KNE02365.1 - 0.00032 20.1 0.1 0.003 17.0 0.0 2.1 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_24 PF13479.6 KNE02365.1 - 0.027 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ssDNA_TraI_N PF18272.1 KNE02365.1 - 0.036 14.1 0.1 0.077 13.0 0.1 1.5 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain PAXNEB PF05625.11 KNE02365.1 - 0.083 12.0 1.0 0.32 10.1 0.1 2.1 2 1 0 2 2 2 0 PAXNEB protein AAA_22 PF13401.6 KNE02365.1 - 0.11 12.7 0.1 0.35 11.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain Mcl1_mid PF12341.8 KNE02366.1 - 7.8e-71 238.8 0.0 1.5e-70 237.9 0.0 1.5 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 KNE02366.1 - 2.7e-06 27.6 0.0 0.11 12.9 0.0 4.1 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 KNE02366.1 - 0.01 15.1 0.1 0.022 14.0 0.1 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Gal4_dimer PF03902.13 KNE02366.1 - 0.05 13.8 0.1 0.16 12.2 0.1 1.8 1 0 0 1 1 1 0 Gal4-like dimerisation domain Tom5 PF10642.9 KNE02367.1 - 1.4e-14 53.8 0.1 1.5e-14 53.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase TMEM70 PF06979.12 KNE02367.1 - 0.046 14.1 0.0 0.049 14.0 0.0 1.1 1 0 0 1 1 1 0 Assembly, mitochondrial proton-transport ATP synth complex Acetyltransf_1 PF00583.25 KNE02368.1 - 2.7e-08 34.0 0.0 3.7e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KNE02368.1 - 1.8e-06 27.9 0.0 2.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KNE02368.1 - 7.5e-06 25.9 0.0 1.2e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KNE02368.1 - 0.00011 22.5 0.0 0.00016 22.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KNE02368.1 - 0.0044 17.2 0.0 0.006 16.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain IFRD PF05004.13 KNE02369.1 - 1.6e-16 60.3 2.9 4.1e-14 52.4 0.1 2.3 2 0 0 2 2 2 2 Interferon-related developmental regulator (IFRD) SUR7 PF06687.12 KNE02370.1 - 1.7e-27 96.4 5.5 2.5e-27 95.9 5.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF2721 PF11026.8 KNE02370.1 - 0.0059 16.5 0.9 0.0059 16.5 0.9 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2721) TauD PF02668.16 KNE02371.1 - 7.2e-56 189.9 1.7 9.5e-56 189.5 1.7 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TOPRIM_C PF16898.5 KNE02371.1 - 0.07 13.4 0.1 3.8 7.8 0.0 2.7 2 0 0 2 2 2 0 C-terminal associated domain of TOPRIM Tht1 PF04163.12 KNE02373.1 - 3.3e-23 82.3 19.1 1.2e-22 80.4 19.1 1.8 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein MCPVI PF02993.14 KNE02373.1 - 0.0049 16.7 0.1 0.0086 15.9 0.1 1.3 1 0 0 1 1 1 1 Minor capsid protein VI Snapin_Pallidin PF14712.6 KNE02373.1 - 0.34 11.3 11.4 1.2 9.6 0.2 3.3 3 0 0 3 3 3 0 Snapin/Pallidin DUF1664 PF07889.12 KNE02373.1 - 1.7 8.7 6.3 0.88 9.6 0.9 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Lipase_3 PF01764.25 KNE02374.1 - 8.6e-31 106.7 0.0 1.6e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.20 KNE02374.1 - 5.8e-05 22.9 0.0 9.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 KNE02374.1 - 7.5e-05 23.4 0.0 9.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KNE02374.1 - 0.0017 18.1 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 KNE02374.1 - 0.0026 17.1 0.0 0.0041 16.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KNE02374.1 - 0.031 14.4 0.0 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF2974 PF11187.8 KNE02374.1 - 0.097 12.2 0.1 0.7 9.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Calcipressin PF04847.12 KNE02376.1 - 6.5e-07 29.3 0.1 1.3e-06 28.3 0.1 1.6 1 1 0 1 1 1 1 Calcipressin Spore_YhaL PF14147.6 KNE02376.1 - 0.079 12.7 2.1 0.19 11.4 2.1 1.6 1 0 0 1 1 1 0 Sporulation protein YhaL Ribosomal_L1 PF00687.21 KNE02377.1 - 8.6e-37 126.9 1.3 1.4e-36 126.2 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Cwf_Cwc_15 PF04889.12 KNE02377.1 - 0.34 10.6 11.1 0.71 9.6 11.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIIC_delta PF12657.7 KNE02378.1 - 0.058 13.3 0.1 0.22 11.4 0.1 2.0 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term HSF_DNA-bind PF00447.17 KNE02379.1 - 4.6e-31 107.3 3.0 1.8e-30 105.4 3.0 2.1 1 0 0 1 1 1 1 HSF-type DNA-binding Folliculin PF11704.8 KNE02379.1 - 0.51 10.2 6.2 0.43 10.4 3.6 2.1 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport YabA PF06156.13 KNE02379.1 - 0.94 10.1 5.6 1.1 9.9 0.1 2.8 2 0 0 2 2 2 0 Initiation control protein YabA Copper-fist PF00649.18 KNE02380.1 - 5.6e-20 70.5 2.4 1.3e-19 69.4 2.4 1.7 1 0 0 1 1 1 1 Copper fist DNA binding domain tRNA-synt_2c PF01411.19 KNE02381.1 - 5.4e-224 744.8 0.0 5.4e-224 744.8 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KNE02381.1 - 4.8e-18 65.0 0.1 1.6e-17 63.3 0.1 2.0 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KNE02381.1 - 5e-14 52.9 5.5 1.4e-13 51.5 5.5 1.8 1 0 0 1 1 1 1 DHHA1 domain DUF4735 PF15882.5 KNE02381.1 - 0.18 11.3 0.4 0.29 10.6 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) TGBp3 PF02495.17 KNE02381.1 - 0.22 11.2 0.0 0.44 10.2 0.0 1.4 1 0 0 1 1 1 0 Triple gene block 3 Histone_HNS PF00816.21 KNE02381.1 - 7.8 7.4 6.8 28 5.6 0.1 3.2 2 1 0 2 2 2 0 H-NS histone family MoCF_biosynth PF00994.24 KNE02382.1 - 1.4e-28 99.4 0.0 2.3e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Ndc80_HEC PF03801.13 KNE02382.1 - 0.025 14.2 0.0 0.07 12.8 0.0 1.7 2 0 0 2 2 2 0 HEC/Ndc80p family Metallophos PF00149.28 KNE02384.1 - 3.1e-41 142.1 2.6 4.1e-41 141.7 2.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ABC2_membrane PF01061.24 KNE02386.1 - 4.4e-70 235.4 63.4 9.4e-42 142.8 19.2 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KNE02386.1 - 4.2e-38 130.9 0.0 9.5e-19 68.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KNE02386.1 - 3.2e-31 107.1 7.6 1.5e-26 92.1 0.0 3.3 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KNE02386.1 - 5.3e-09 36.6 0.0 1.3e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KNE02386.1 - 7.8e-09 35.1 13.2 7.8e-09 35.1 13.2 3.4 2 2 1 3 3 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KNE02386.1 - 1.3e-06 28.4 1.7 0.00022 21.2 0.0 2.6 3 0 0 3 3 2 1 RsgA GTPase AAA_16 PF13191.6 KNE02386.1 - 8.5e-05 23.0 0.0 0.013 15.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 KNE02386.1 - 0.00019 21.5 0.8 0.67 10.1 0.2 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KNE02386.1 - 0.00026 20.7 0.2 0.25 11.1 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KNE02386.1 - 0.00038 20.4 0.1 0.99 9.2 0.0 2.5 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KNE02386.1 - 0.00073 20.1 0.0 0.037 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KNE02386.1 - 0.0032 17.7 0.1 0.19 12.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 KNE02386.1 - 0.0046 16.6 0.3 0.033 13.8 0.1 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KNE02386.1 - 0.0056 16.1 0.0 1.2 8.5 0.0 3.3 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KNE02386.1 - 0.0062 16.3 0.3 0.54 9.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KNE02386.1 - 0.0079 16.4 0.1 0.3 11.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 KNE02386.1 - 0.025 15.1 5.6 0.21 12.1 0.0 3.4 4 0 0 4 4 4 0 AAA domain cobW PF02492.19 KNE02386.1 - 0.028 14.0 1.2 0.065 12.8 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KNE02386.1 - 0.066 13.1 1.7 0.39 10.6 0.2 2.7 2 0 0 2 2 2 0 NACHT domain ABC_ATPase PF09818.9 KNE02386.1 - 0.073 11.9 0.1 0.14 10.9 0.1 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class TsaE PF02367.17 KNE02386.1 - 0.12 12.4 0.5 0.5 10.4 0.1 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ferlin_C PF16165.5 KNE02386.1 - 2.4 8.1 5.5 8.1 6.4 0.1 3.7 4 0 0 4 4 4 0 Ferlin C-terminus Cyclin PF08613.11 KNE02387.1 - 2.1e-36 125.8 0.0 3.1e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KNE02387.1 - 0.0024 17.6 0.3 0.0035 17.1 0.3 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Vac7 PF12751.7 KNE02387.1 - 0.06 12.8 0.0 0.081 12.4 0.0 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 DUF2439 PF10382.9 KNE02388.1 - 2.2e-18 66.4 0.0 4.2e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Ribosomal_L5_C PF00673.21 KNE02389.1 - 7.6e-28 96.5 0.0 1.3e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KNE02389.1 - 0.012 16.0 0.2 0.035 14.4 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L5 GLE1 PF07817.13 KNE02390.1 - 9.7e-71 237.9 0.3 9.7e-71 237.9 0.3 2.1 2 0 0 2 2 2 1 GLE1-like protein CDC45 PF02724.14 KNE02390.1 - 0.14 10.4 13.5 0.18 10.1 13.5 1.3 1 0 0 1 1 1 0 CDC45-like protein CCDC71L PF15374.6 KNE02390.1 - 0.74 9.0 15.1 1.1 8.5 15.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L Presenilin PF01080.17 KNE02390.1 - 1.2 7.8 12.1 1.5 7.5 12.1 1.3 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 KNE02390.1 - 5 6.9 22.0 8.6 6.1 22.0 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HEAT PF02985.22 KNE02391.1 - 0.00012 22.0 0.1 1.9 9.0 0.0 4.2 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 KNE02391.1 - 0.00016 22.0 0.0 0.016 15.6 0.0 3.5 2 0 0 2 2 2 1 HEAT repeats RICTOR_M PF14666.6 KNE02391.1 - 0.013 15.2 0.1 6.9 6.5 0.0 3.8 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain Pkinase PF00069.25 KNE02396.1 - 4.1e-67 226.3 0.0 6.8e-67 225.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE02396.1 - 1.1e-40 139.6 0.0 1.7e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNE02396.1 - 3e-09 36.6 0.0 5.2e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KNE02396.1 - 0.00056 19.3 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KNE02396.1 - 0.0017 17.4 0.2 0.0052 15.8 0.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KNE02396.1 - 0.013 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family R3H PF01424.22 KNE02398.1 - 9.2e-15 54.4 0.1 1.8e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 R3H domain Fcf1 PF04900.12 KNE02399.1 - 2.6e-34 117.6 0.1 4.1e-34 116.9 0.1 1.3 1 0 0 1 1 1 1 Fcf1 DUF908 PF06012.12 KNE02399.1 - 0.0072 15.8 0.5 0.0085 15.5 0.5 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) PIN_9 PF18477.1 KNE02399.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 PIN like domain TFIIS_C PF01096.18 KNE02400.1 - 6.8e-19 67.4 6.8 2.9e-17 62.2 2.1 3.2 3 1 1 4 4 4 2 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KNE02400.1 - 3.4e-08 33.2 6.6 7.4e-06 25.7 0.3 3.0 3 0 0 3 3 3 2 RNA polymerases M/15 Kd subunit DZR PF12773.7 KNE02400.1 - 0.00028 20.8 6.6 0.087 12.9 0.2 2.8 2 1 0 2 2 2 2 Double zinc ribbon C1_1 PF00130.22 KNE02400.1 - 0.0003 20.6 3.9 0.029 14.3 0.1 2.4 2 1 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Baculo_LEF5_C PF11792.8 KNE02400.1 - 0.0016 18.1 5.2 0.015 15.0 1.1 2.8 2 1 1 3 3 3 2 Baculoviridae late expression factor 5 C-terminal domain zf-ribbon_3 PF13248.6 KNE02400.1 - 0.0038 16.6 5.8 5.2 6.6 0.5 3.5 3 0 0 3 3 3 2 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KNE02400.1 - 0.01 15.5 9.1 4.3 7.2 0.3 3.6 3 1 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KNE02400.1 - 0.026 14.7 9.8 2.7 8.2 0.3 3.3 3 0 0 3 3 3 0 Zinc ribbon domain Elf1 PF05129.13 KNE02400.1 - 0.12 12.4 4.9 0.87 9.7 0.4 2.5 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like DUF3716 PF12511.8 KNE02400.1 - 0.13 12.3 5.2 0.14 12.3 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) TF_Zn_Ribbon PF08271.12 KNE02400.1 - 0.18 11.3 13.4 0.36 10.4 2.7 3.4 2 2 1 3 3 3 0 TFIIB zinc-binding Ogr_Delta PF04606.12 KNE02400.1 - 0.34 10.9 4.7 0.9 9.6 4.7 1.8 1 1 0 1 1 1 0 Ogr/Delta-like zinc finger IBR PF01485.21 KNE02400.1 - 0.36 11.1 7.5 7 7.0 0.1 2.7 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain YhfH PF14149.6 KNE02400.1 - 0.56 10.2 6.8 28 4.8 0.1 3.4 3 0 0 3 3 3 0 YhfH-like protein DUF951 PF06107.11 KNE02400.1 - 0.71 9.8 0.1 0.71 9.8 0.1 3.0 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF951) Stc1 PF12898.7 KNE02400.1 - 0.97 10.0 7.9 0.43 11.1 0.5 2.4 1 1 1 2 2 2 0 Stc1 domain zinc_ribbon_4 PF13717.6 KNE02400.1 - 1 9.3 7.7 7 6.7 0.1 3.4 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 KNE02400.1 - 2 8.5 7.3 1.9 8.6 0.8 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Sgf11 PF08209.11 KNE02400.1 - 3.2 7.4 8.5 9.2 5.9 0.1 3.1 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zf-P11 PF03854.14 KNE02400.1 - 4.2 7.1 8.0 0.15 11.8 0.8 2.2 3 0 0 3 3 3 0 P-11 zinc finger Rubredoxin_2 PF18073.1 KNE02400.1 - 8.8 6.2 15.5 1.3 8.8 1.3 3.7 4 0 0 4 4 4 0 Rubredoxin metal binding domain HEAT_2 PF13646.6 KNE02401.1 - 4e-30 104.0 0.3 2e-12 47.4 0.0 3.9 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.16 KNE02401.1 - 3.2e-21 73.8 0.1 4e-05 23.9 0.0 7.3 8 0 0 8 8 8 4 PBS lyase HEAT-like repeat HEAT PF02985.22 KNE02401.1 - 1.5e-11 43.5 1.5 1 9.8 0.0 7.3 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 KNE02401.1 - 4.3e-06 27.1 0.4 0.92 10.1 0.0 4.7 5 1 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 KNE02401.1 - 0.0016 18.5 3.4 1.5 8.8 0.3 3.9 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 PcfK PF14058.6 KNE02401.1 - 0.042 14.1 2.0 0.068 13.4 2.0 1.4 1 0 0 1 1 1 0 PcfK-like protein Cpn60_TCP1 PF00118.24 KNE02402.1 - 1.3e-151 505.6 9.4 1.5e-151 505.4 9.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cation_ATPase PF13246.6 KNE02402.1 - 0.026 14.6 0.0 0.1 12.7 0.0 2.0 2 0 0 2 2 2 0 Cation transport ATPase (P-type) Actin PF00022.19 KNE02403.1 - 1.9e-89 300.1 0.0 2.7e-54 184.4 0.0 2.0 1 1 1 2 2 2 2 Actin FtsA PF14450.6 KNE02403.1 - 0.0016 18.9 0.0 0.0087 16.5 0.0 2.2 2 1 0 2 2 2 1 Cell division protein FtsA MreB_Mbl PF06723.13 KNE02403.1 - 0.0055 15.6 0.0 0.29 9.9 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FAT PF02259.23 KNE02404.1 - 4.6e-144 479.9 2.8 4.6e-144 479.9 2.8 2.2 3 0 0 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.27 KNE02404.1 - 5.8e-71 239.2 0.0 1.3e-70 238.1 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KNE02404.1 - 2.8e-70 235.4 10.1 2e-63 213.1 0.5 5.6 4 1 1 5 5 5 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KNE02404.1 - 2.8e-43 146.3 3.2 2.3e-42 143.4 0.7 3.3 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 KNE02404.1 - 2.3e-16 59.3 0.3 7.2e-16 57.7 0.3 2.0 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 KNE02404.1 - 3.6e-11 42.3 8.7 0.0048 17.0 0.0 8.5 9 0 0 9 9 7 2 HEAT repeat HEAT_2 PF13646.6 KNE02404.1 - 1.7e-10 41.1 7.4 0.055 13.9 0.0 8.9 7 3 2 9 9 8 2 HEAT repeats Cnd1 PF12717.7 KNE02404.1 - 3.9e-05 23.8 4.4 0.001 19.1 0.5 4.5 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 TPR_19 PF14559.6 KNE02404.1 - 0.00012 22.5 0.1 4 8.0 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat HEAT_EZ PF13513.6 KNE02404.1 - 0.00035 21.0 18.3 0.00057 20.3 0.0 7.9 9 1 1 10 10 8 2 HEAT-like repeat IFRD PF05004.13 KNE02404.1 - 0.0027 16.9 1.3 0.027 13.6 0.1 3.3 3 0 0 3 3 3 1 Interferon-related developmental regulator (IFRD) TPR_14 PF13428.6 KNE02404.1 - 0.0046 17.7 0.3 1.6 9.7 0.0 4.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KNE02404.1 - 0.0075 16.9 0.1 0.76 10.5 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat Cnd3 PF12719.7 KNE02404.1 - 0.017 14.3 1.5 0.3 10.2 0.1 3.4 3 1 1 4 4 4 0 Nuclear condensing complex subunits, C-term domain DUF1127 PF06568.11 KNE02404.1 - 0.11 12.3 1.3 0.39 10.5 0.1 2.8 2 0 0 2 2 1 0 Domain of unknown function (DUF1127) ANAPC3 PF12895.7 KNE02404.1 - 0.14 12.4 2.2 17 5.7 0.1 4.4 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Vac14_Fab1_bd PF12755.7 KNE02404.1 - 0.38 11.4 7.9 11 6.7 0.0 5.9 5 3 1 6 6 5 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.16 KNE02404.1 - 5.8 7.9 8.4 53 4.9 0.0 6.0 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat TPR_2 PF07719.17 KNE02404.1 - 8 6.9 6.5 31 5.0 0.2 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat RTC PF01137.21 KNE02405.1 - 1.2e-39 135.8 0.0 1.4e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KNE02405.1 - 5.6e-31 107.1 0.0 8.7e-31 106.5 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain HTH_Tnp_ISL3 PF13542.6 KNE02405.1 - 0.1 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 TAF4 PF05236.14 KNE02406.1 - 2.2e-63 214.6 0.6 2.2e-63 214.6 0.6 1.5 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family DUF1082 PF06449.11 KNE02406.1 - 0.2 11.5 1.4 0.6 10.0 1.4 1.8 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1082) Cnd1 PF12717.7 KNE02407.1 - 3.8e-44 150.6 13.4 1.4e-42 145.5 1.5 5.3 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 KNE02407.1 - 8.7e-33 113.5 2.9 1.6e-32 112.7 0.4 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 KNE02407.1 - 2.2e-06 27.5 1.1 0.53 10.7 0.0 5.9 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 KNE02407.1 - 2.7e-06 27.7 0.0 0.06 13.7 0.0 3.9 2 1 1 3 3 3 2 HEAT repeats Cnd3 PF12719.7 KNE02407.1 - 0.00018 20.8 3.1 0.00018 20.8 3.1 4.4 3 2 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain EspA PF03433.13 KNE02407.1 - 0.043 13.7 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 EspA-like secreted protein HEAT_EZ PF13513.6 KNE02407.1 - 0.053 14.0 0.4 24 5.5 0.0 4.8 6 0 0 6 6 6 0 HEAT-like repeat MBOAT PF03062.19 KNE02408.1 - 1.1e-63 215.7 3.5 1.1e-63 215.7 3.5 1.6 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MutS_IV PF05190.18 KNE02408.1 - 0.061 13.7 0.6 0.061 13.7 0.6 2.0 2 0 0 2 2 2 0 MutS family domain IV CheZ PF04344.13 KNE02408.1 - 0.081 12.8 0.8 0.17 11.8 0.4 1.5 1 1 0 1 1 1 0 Chemotaxis phosphatase, CheZ DUF2884 PF11101.8 KNE02408.1 - 1.7 8.1 5.7 3.9 6.9 5.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) Ferrochelatase PF00762.19 KNE02409.1 - 7.7e-93 311.0 0.0 9e-93 310.8 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase RE_EcoO109I PF14511.6 KNE02409.1 - 0.18 11.4 0.1 2.7 7.5 0.0 2.4 3 0 0 3 3 3 0 Type II restriction endonuclease EcoO109I Med4 PF10018.9 KNE02411.1 - 6.4e-24 84.7 1.9 8.9e-24 84.2 1.9 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Phage_lysis PF03245.13 KNE02411.1 - 0.14 12.3 0.5 0.14 12.3 0.5 1.9 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein FlaC_arch PF05377.11 KNE02411.1 - 0.15 12.4 2.5 2.6 8.5 0.2 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF4187 PF13821.6 KNE02412.1 - 4.7e-14 51.9 2.0 4.7e-14 51.9 2.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KNE02412.1 - 8.7e-08 31.9 0.1 1.5e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KNE02412.1 - 0.0063 16.6 0.7 0.015 15.3 0.0 2.0 2 0 0 2 2 2 1 G-patch domain zf-C2H2_jaz PF12171.8 KNE02412.1 - 0.14 12.5 0.5 0.26 11.6 0.5 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding RRM_1 PF00076.22 KNE02413.1 - 8.4e-33 112.0 0.0 2.5e-15 56.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KNE02413.1 - 0.0036 17.3 0.1 0.04 13.9 0.0 2.6 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KNE02413.1 - 0.0084 16.1 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif RRM_7 PF16367.5 KNE02413.1 - 0.014 15.5 0.0 0.13 12.4 0.0 2.5 4 0 0 4 4 4 0 RNA recognition motif NDUF_B8 PF05821.11 KNE02415.1 - 2.6e-10 40.5 0.5 3.6e-10 40.0 0.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.23 KNE02416.1 - 7.1e-66 222.3 0.1 1.7e-65 221.1 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KNE02416.1 - 3e-18 66.2 0.0 3.1e-17 62.9 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNE02416.1 - 3.5e-12 46.7 1.0 1.3e-11 44.8 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HSA PF07529.13 KNE02416.1 - 4.5e-12 46.1 7.8 4.5e-12 46.1 7.8 3.3 2 0 0 2 2 2 1 HSA DEAD PF00270.29 KNE02416.1 - 0.0001 22.1 0.0 0.00028 20.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase V-ATPase_G PF03179.15 KNE02417.1 - 2.5e-30 105.1 19.7 2.7e-30 105.0 19.7 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit V-ATPase_G_2 PF16999.5 KNE02417.1 - 0.00059 20.2 16.6 0.00066 20.1 16.6 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 KNE02417.1 - 0.0079 16.3 8.8 0.0079 16.3 8.8 2.1 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) AAA-ATPase_like PF09820.9 KNE02417.1 - 0.069 12.6 4.0 0.073 12.5 4.0 1.1 1 0 0 1 1 1 0 Predicted AAA-ATPase OmpH PF03938.14 KNE02417.1 - 0.11 12.9 20.3 0.15 12.4 20.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RE_AlwI PF09491.10 KNE02417.1 - 0.14 10.9 13.4 0.71 8.6 13.4 1.8 1 1 0 1 1 1 0 AlwI restriction endonuclease DUF3381 PF11861.8 KNE02417.1 - 0.19 11.5 16.8 0.27 11.0 16.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Exonuc_VII_L PF02601.15 KNE02417.1 - 0.28 10.7 7.9 0.31 10.6 7.9 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit RRF PF01765.19 KNE02417.1 - 0.39 10.6 15.5 0.57 10.1 15.5 1.3 1 0 0 1 1 1 0 Ribosome recycling factor GBP_C PF02841.14 KNE02417.1 - 0.42 10.0 16.4 0.45 9.9 16.4 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Mst1_SARAH PF11629.8 KNE02417.1 - 0.48 10.6 8.6 0.1 12.7 4.3 2.2 1 1 2 3 3 3 0 C terminal SARAH domain of Mst1 DUF3552 PF12072.8 KNE02417.1 - 0.85 9.0 22.9 1.6 8.1 22.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) vATP-synt_E PF01991.18 KNE02417.1 - 1.2 8.4 22.1 2 7.8 22.1 1.3 1 1 0 1 1 1 0 ATP synthase (E/31 kDa) subunit DUF16 PF01519.16 KNE02417.1 - 1.3 9.6 15.4 1.2 9.6 14.7 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF4746 PF15928.5 KNE02417.1 - 1.6 8.1 13.1 1.9 7.8 13.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PEPcase_2 PF14010.6 KNE02417.1 - 2 6.8 8.9 2.3 6.6 8.9 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase HSP70 PF00012.20 KNE02417.1 - 3.2 5.8 14.2 3.8 5.6 14.2 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF4407 PF14362.6 KNE02417.1 - 3.2 7.0 10.3 4.5 6.5 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3391 PF11871.8 KNE02417.1 - 3.3 8.3 11.9 6 7.4 11.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) Atg14 PF10186.9 KNE02417.1 - 3.6 6.6 13.7 4.1 6.4 13.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF883 PF05957.13 KNE02417.1 - 4 8.1 11.7 5.4 7.7 4.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Casc1_N PF15927.5 KNE02417.1 - 6.7 6.3 18.9 0.78 9.4 12.1 1.9 1 1 1 2 2 2 0 Cancer susceptibility candidate 1 N-terminus CemA PF03040.14 KNE02417.1 - 8.2 6.3 8.9 11 5.8 8.9 1.3 1 0 0 1 1 1 0 CemA family Aldedh PF00171.22 KNE02418.1 - 7.2e-123 410.5 0.0 8.7e-123 410.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Toxin_33 PF08121.11 KNE02418.1 - 0.18 11.6 0.5 0.48 10.3 0.5 1.7 1 0 0 1 1 1 0 Waglerin family Tcf25 PF04910.14 KNE02419.1 - 3.5e-87 292.7 0.6 5e-87 292.2 0.6 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Acetyltransf_6 PF13480.7 KNE02419.1 - 0.12 12.6 0.3 0.45 10.7 0.3 2.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Rrn6 PF10214.9 KNE02419.1 - 0.19 10.2 4.6 0.3 9.5 4.6 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PGA2 PF07543.12 KNE02419.1 - 5.8 6.9 16.1 0.065 13.2 7.2 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 SBDS PF01172.18 KNE02420.1 - 7e-21 74.1 0.1 8.2e-21 73.9 0.1 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Arf PF00025.21 KNE02422.1 - 3.3e-48 163.4 0.0 3.7e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KNE02422.1 - 6.9e-09 35.3 0.0 1.3e-08 34.5 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit Ras PF00071.22 KNE02422.1 - 0.00035 20.2 0.0 0.00036 20.2 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KNE02422.1 - 0.00087 18.8 0.0 0.0012 18.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KNE02422.1 - 0.0011 19.2 0.0 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KNE02422.1 - 0.09 12.3 0.0 0.094 12.2 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KNE02422.1 - 0.093 12.8 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase FMO-like PF00743.19 KNE02423.1 - 8.1e-30 103.7 0.0 6.4e-11 41.4 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KNE02423.1 - 3.4e-20 72.5 0.2 2.8e-14 53.1 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KNE02423.1 - 9.9e-15 54.5 0.0 4e-13 49.3 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KNE02423.1 - 1e-10 41.8 0.0 1.5e-09 38.0 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KNE02423.1 - 2e-09 37.5 0.0 0.0033 17.1 0.0 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KNE02423.1 - 2.2e-08 34.2 0.0 6.1e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KNE02423.1 - 1.7e-06 27.4 0.1 0.00078 18.7 0.0 3.4 2 1 1 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KNE02423.1 - 2.5e-06 26.9 0.4 0.00029 20.2 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KNE02423.1 - 2.4e-05 24.8 0.5 1 10.0 0.0 3.7 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KNE02423.1 - 8.6e-05 21.4 0.0 0.021 13.5 0.1 2.4 2 1 0 2 2 2 2 HI0933-like protein Amino_oxidase PF01593.24 KNE02423.1 - 0.00024 20.5 0.0 0.36 10.0 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KNE02423.1 - 0.0051 16.2 0.0 0.013 14.9 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KNE02423.1 - 0.043 12.9 0.0 0.33 10.0 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain DUF4202 PF13875.6 KNE02423.1 - 0.057 13.3 0.1 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4202) She9_MDM33 PF05546.11 KNE02423.1 - 0.073 12.9 0.8 0.3 10.8 0.2 2.0 2 0 0 2 2 2 0 She9 / Mdm33 family FAD_binding_3 PF01494.19 KNE02423.1 - 0.11 11.8 0.2 0.2 10.9 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KNE02423.1 - 0.26 10.3 0.1 1.1 8.2 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Ald_deCOase PF11266.8 KNE02424.1 - 0.077 12.7 0.0 0.077 12.7 0.0 1.0 1 0 0 1 1 1 0 Long-chain fatty aldehyde decarbonylase BRCT_assoc PF12820.7 KNE02426.1 - 0.21 11.4 1.5 0.4 10.5 0.0 2.1 2 1 1 3 3 3 0 Serine-rich domain associated with BRCT Fructosamin_kin PF03881.14 KNE02427.1 - 0.001 18.3 0.0 0.0022 17.3 0.0 1.5 1 0 0 1 1 1 1 Fructosamine kinase Kdo PF06293.14 KNE02427.1 - 0.018 14.4 0.0 0.092 12.1 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sedlin_N PF04628.13 KNE02428.1 - 3.7e-45 153.2 0.0 4.5e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KNE02428.1 - 0.00078 19.4 1.5 0.0026 17.7 0.3 2.3 2 1 0 2 2 2 1 Sybindin-like family NurA PF09376.10 KNE02429.1 - 2.2 7.9 5.9 23 4.6 5.9 2.2 1 1 0 1 1 1 0 NurA domain SSXT PF05030.12 KNE02430.1 - 0.054 13.1 0.1 0.056 13.1 0.1 1.1 1 0 0 1 1 1 0 SSXT protein (N-terminal region) EssA PF10661.9 KNE02431.1 - 0.25 11.2 2.7 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA Paramyxo_ncap PF00973.19 KNE02431.1 - 1.4 7.7 5.5 2.4 7.0 5.5 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein GET2 PF08690.10 KNE02431.1 - 1.8 8.1 7.2 4.1 7.0 7.2 1.5 1 0 0 1 1 1 0 GET complex subunit GET2 PITH PF06201.13 KNE02432.1 - 4.3e-26 91.9 0.5 8.8e-26 90.9 0.5 1.5 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 KNE02432.1 - 1e-23 83.3 0.1 2.2e-23 82.2 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KNE02432.1 - 2.9e-09 37.3 0.4 1.8e-08 34.8 0.1 2.3 2 1 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KNE02432.1 - 6.4e-07 29.0 0.2 9.9e-07 28.4 0.2 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KNE02432.1 - 7e-07 29.5 0.0 2.6e-05 24.4 0.0 2.6 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KNE02432.1 - 6.2e-05 22.8 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 KNE02432.1 - 0.00062 19.9 0.1 0.0013 18.8 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KNE02432.1 - 0.011 15.7 0.1 0.029 14.3 0.1 1.7 1 0 0 1 1 1 0 AhpC/TSA family HyaE PF07449.11 KNE02432.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 KNE02432.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain DUF836 PF05768.14 KNE02432.1 - 0.13 12.7 0.0 0.45 11.0 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KNE02432.1 - 0.18 12.0 0.2 0.91 9.8 0.0 2.2 2 0 0 2 2 2 0 Glutaredoxin LETM1 PF07766.13 KNE02433.1 - 3.8e-97 324.8 2.1 3.8e-97 324.8 2.1 1.5 2 0 0 2 2 2 1 LETM1-like protein dUTPase PF00692.19 KNE02434.1 - 1.9e-47 160.2 0.0 2.2e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 dUTPase DUF2951 PF11166.8 KNE02436.1 - 0.021 15.0 1.5 2.5 8.4 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) CAF1A PF12253.8 KNE02437.1 - 3.4e-22 78.4 7.5 3.4e-22 78.4 7.5 4.1 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A TetR_C_8 PF14278.6 KNE02437.1 - 0.0045 17.1 1.3 0.0089 16.1 0.2 2.1 2 0 0 2 2 2 1 Transcriptional regulator C-terminal region Borrelia_P83 PF05262.11 KNE02437.1 - 6.5 5.1 40.6 14 4.0 40.6 1.6 1 0 0 1 1 1 0 Borrelia P83/100 protein Slx4 PF09494.10 KNE02438.1 - 2.4e-09 37.0 0.0 5.3e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Slx4 endonuclease OSCP PF00213.18 KNE02438.1 - 0.38 10.9 5.7 1.4 9.0 0.5 3.1 1 1 2 3 3 3 0 ATP synthase delta (OSCP) subunit SLAC1 PF03595.17 KNE02439.1 - 0.0014 17.9 0.3 0.0015 17.8 0.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel JmjC PF02373.22 KNE02440.1 - 9.4e-41 138.8 2.2 9.4e-41 138.8 2.2 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.17 KNE02440.1 - 1.2e-16 60.4 2.0 3.4e-16 58.9 2.0 1.9 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.6 KNE02440.1 - 1.4e-10 41.3 10.0 3e-10 40.2 6.7 2.5 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KNE02440.1 - 8e-10 38.9 6.9 1.8e-09 37.8 4.6 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain Rad17 PF03215.15 KNE02441.1 - 2.6e-28 99.2 0.0 4.3e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KNE02441.1 - 0.02 15.2 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KNE02441.1 - 0.056 13.8 0.1 0.15 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 KNE02441.1 - 0.076 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Glutaredoxin PF00462.24 KNE02442.1 - 7.9e-20 70.8 0.0 1.4e-17 63.7 0.0 2.7 3 0 0 3 3 3 1 Glutaredoxin Thioredoxin PF00085.20 KNE02442.1 - 1.2e-13 50.9 0.0 2.3e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KNE02442.1 - 4.8e-05 23.6 0.0 0.0025 18.1 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KNE02442.1 - 0.00055 20.4 0.0 0.04 14.4 0.0 3.1 3 1 0 3 3 3 1 Thioredoxin-like domain Ribosomal_60s PF00428.19 KNE02442.1 - 0.0048 17.4 1.0 0.01 16.4 1.0 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein Phosducin PF02114.16 KNE02442.1 - 0.011 14.7 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Phosducin Thioredoxin_9 PF14595.6 KNE02442.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin OST3_OST6 PF04756.13 KNE02442.1 - 0.058 12.7 0.0 0.074 12.4 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF4736 PF15883.5 KNE02446.1 - 0.06 13.1 1.1 0.13 12.0 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) DUF1345 PF07077.11 KNE02447.1 - 0.00013 21.7 0.0 0.00014 21.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1345) DUF2207 PF09972.9 KNE02447.1 - 0.0056 15.5 0.1 0.0064 15.3 0.1 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Baculo_11_kDa PF06143.11 KNE02447.1 - 0.022 14.3 0.4 0.62 9.7 0.0 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF2951 PF11166.8 KNE02447.1 - 0.024 14.8 0.2 0.024 14.8 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Vpu PF00558.19 KNE02447.1 - 0.029 14.1 0.1 0.029 14.1 0.1 2.4 2 1 1 3 3 3 0 Vpu protein DUF4199 PF13858.6 KNE02447.1 - 0.15 12.4 4.6 0.22 11.9 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) ABC2_membrane_3 PF12698.7 KNE02447.1 - 0.25 10.4 4.1 4.8 6.2 6.2 1.8 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF4083 PF13314.6 KNE02447.1 - 0.27 11.2 5.0 10 6.1 2.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4083) DUF3270 PF11674.8 KNE02447.1 - 1 9.6 5.8 0.27 11.4 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3270) DUF1201 PF06716.11 KNE02447.1 - 6.2 6.9 13.5 0.091 12.8 2.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1201) DUF4149 PF13664.6 KNE02448.1 - 1.2e-22 80.1 1.1 3e-21 75.6 0.1 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4149) MutS_V PF00488.21 KNE02449.1 - 4.3e-63 212.8 0.9 7.5e-63 212.0 0.9 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KNE02449.1 - 1.5e-34 119.9 0.1 4.4e-34 118.4 0.1 1.9 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KNE02449.1 - 4.1e-32 110.8 0.3 2.7e-31 108.1 0.0 2.3 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 KNE02449.1 - 5.1e-12 46.2 0.1 1.2e-11 45.1 0.1 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KNE02449.1 - 8.4e-11 42.1 1.2 2.6e-10 40.5 0.3 2.4 3 0 0 3 3 3 1 MutS family domain IV AAA_29 PF13555.6 KNE02449.1 - 0.02 14.6 0.1 0.06 13.1 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 KNE02449.1 - 0.056 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KNE02449.1 - 0.059 13.9 0.1 0.059 13.9 0.1 3.1 4 0 0 4 4 4 0 AAA domain AAA_21 PF13304.6 KNE02449.1 - 0.059 13.2 0.1 0.059 13.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NTP_transferase PF00483.23 KNE02451.1 - 1.1e-23 84.1 0.0 1.6e-22 80.3 0.0 2.4 2 1 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 KNE02451.1 - 3.3e-08 32.9 12.9 0.00019 21.0 0.3 4.2 2 1 2 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KNE02451.1 - 0.0064 16.2 7.6 0.15 11.8 5.0 2.8 1 1 1 2 2 2 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KNE02451.1 - 0.094 11.6 0.7 0.33 9.9 0.4 1.9 2 0 0 2 2 2 0 L-fucokinase NTP_transf_3 PF12804.7 KNE02451.1 - 0.22 11.9 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain DUF4954 PF16314.5 KNE02451.1 - 1.9 6.5 6.3 0.53 8.3 2.9 1.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4954) DNA_pol_A_exo1 PF01612.20 KNE02452.1 - 2.9e-05 23.8 0.0 0.00015 21.6 0.0 2.0 1 1 0 1 1 1 1 3'-5' exonuclease RNase_T PF00929.24 KNE02452.1 - 5.8e-05 23.7 0.0 0.00015 22.4 0.0 1.7 1 0 0 1 1 1 1 Exonuclease CHORD PF04968.12 KNE02452.1 - 0.0062 17.2 0.4 0.013 16.2 0.4 1.6 1 0 0 1 1 1 1 CHORD Ank_2 PF12796.7 KNE02453.1 - 1.5e-29 102.4 0.2 1.3e-12 48.2 0.0 3.4 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) DHHC PF01529.20 KNE02453.1 - 3.1e-26 92.0 8.8 3.1e-26 92.0 8.8 2.7 3 0 0 3 3 3 1 DHHC palmitoyltransferase Ank PF00023.30 KNE02453.1 - 5.7e-22 77.1 1.4 0.00048 20.4 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 KNE02453.1 - 9.8e-21 71.6 0.5 0.0031 17.9 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 KNE02453.1 - 1.2e-20 73.5 0.4 3.4e-08 33.9 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KNE02453.1 - 4.8e-20 71.4 0.4 0.00033 20.9 0.0 4.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) DUF4112 PF13430.6 KNE02454.1 - 4.4e-27 94.4 0.3 6.2e-27 93.9 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) CCDC53 PF10152.9 KNE02455.1 - 0.044 14.2 0.4 0.044 14.2 0.4 2.0 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex CTP_transf_like PF01467.26 KNE02458.1 - 1.7e-06 28.3 0.0 3.1e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Cytidylyltransferase-like Recep_L_domain PF01030.24 KNE02459.1 - 9.7e-10 38.6 6.6 0.00083 19.5 0.1 4.5 1 1 2 4 4 4 4 Receptor L domain PP2C PF00481.21 KNE02462.1 - 2.2e-09 37.3 1.9 0.00082 19.1 0.4 2.2 1 1 1 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 KNE02462.1 - 3.3e-09 36.9 0.0 6.7e-09 35.9 0.0 1.5 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KNE02462.1 - 1.9e-06 27.7 0.0 3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C UPF0239 PF06783.11 KNE02463.1 - 6.4 7.0 8.0 8.7 6.6 8.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) EPSP_synthase PF00275.20 KNE02464.1 - 1.1e-132 442.7 0.2 1.7e-132 442.1 0.2 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KNE02464.1 - 4.8e-100 334.1 0.3 1.3e-99 332.6 0.1 1.8 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KNE02464.1 - 1.2e-45 156.5 0.6 2.5e-44 152.2 0.0 3.2 4 0 0 4 4 4 1 Type I 3-dehydroquinase SKI PF01202.22 KNE02464.1 - 3.7e-38 131.1 0.4 1.5e-37 129.1 0.0 2.2 3 0 0 3 3 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KNE02464.1 - 4.1e-21 75.0 0.0 1.4e-20 73.3 0.0 2.0 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 KNE02464.1 - 6.8e-10 39.1 0.2 2.9e-09 37.0 0.1 2.2 2 1 0 2 2 2 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 KNE02464.1 - 7.9e-08 31.9 0.0 1.7e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KNE02464.1 - 1.2e-07 31.8 0.0 3.2e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH PF00465.19 KNE02464.1 - 6.7e-05 21.9 0.5 0.00024 20.0 0.3 1.9 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_33 PF13671.6 KNE02464.1 - 0.0027 17.9 0.0 0.011 15.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KNE02464.1 - 0.0044 17.6 0.1 0.014 15.9 0.1 1.9 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 KNE02464.1 - 0.04 13.6 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase GARS_N PF02844.15 KNE02464.1 - 0.042 14.6 0.1 0.27 12.0 0.1 2.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain DUF503 PF04456.12 KNE02464.1 - 0.1 12.5 0.1 0.27 11.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF503) Pyr_redox_2 PF07992.14 KNE02464.1 - 0.13 11.4 0.7 1.7 7.8 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KNE02464.1 - 7.2 7.2 7.0 2.5 8.7 0.2 3.4 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase PolyA_pol PF01743.20 KNE02466.1 - 2.9e-31 108.5 0.0 5.9e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KNE02466.1 - 1.7e-10 40.5 0.0 3.6e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 KNE02466.1 - 0.023 14.7 0.1 0.062 13.3 0.0 1.8 2 0 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative ArfGap PF01412.18 KNE02467.1 - 1.7e-27 95.8 1.5 1.7e-27 95.8 1.5 3.0 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf PH PF00169.29 KNE02467.1 - 2.3e-12 47.3 0.0 8.7e-12 45.5 0.0 2.1 1 0 0 1 1 1 1 PH domain BAR_3 PF16746.5 KNE02467.1 - 3e-09 36.9 10.6 6.8e-09 35.8 10.6 1.6 1 0 0 1 1 1 1 BAR domain of APPL family PH_9 PF15410.6 KNE02467.1 - 5.2e-05 23.6 0.1 0.00025 21.4 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 KNE02467.1 - 0.00023 21.4 0.0 0.00063 20.0 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain DUF2205 PF10224.9 KNE02467.1 - 0.12 12.4 1.9 3.9 7.5 0.1 2.9 2 0 0 2 2 2 0 Short coiled-coil protein MAT1 PF06391.13 KNE02468.1 - 1e-57 195.3 29.2 1.3e-57 195.0 29.2 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 Spc7 PF08317.11 KNE02468.1 - 0.31 9.9 23.1 0.45 9.3 23.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FUSC PF04632.12 KNE02468.1 - 2.2 6.7 3.4 2.7 6.4 3.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cgr1 PF03879.14 KNE02469.1 - 0.046 14.1 7.2 0.088 13.2 7.2 1.5 1 0 0 1 1 1 0 Cgr1 family CGI-121 PF08617.10 KNE02470.1 - 2.8e-33 115.4 2.8 3.4e-33 115.0 2.8 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Blo-t-5 PF11642.8 KNE02470.1 - 0.045 13.7 0.1 0.066 13.2 0.1 1.3 1 0 0 1 1 1 0 Mite allergen Blo t 5 XPG_N PF00752.17 KNE02471.1 - 1.9e-22 79.6 0.0 1.1e-21 77.1 0.0 2.3 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 KNE02471.1 - 1e-21 77.1 0.0 3.7e-21 75.3 0.0 2.1 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 KNE02471.1 - 3.3e-08 34.0 0.1 3.4e-06 27.5 0.0 2.7 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 KNE02471.1 - 1.3e-05 25.2 0.1 0.0037 17.3 0.0 3.1 3 0 0 3 3 3 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KNE02471.1 - 0.0083 16.7 0.1 0.76 10.4 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain XPG_I_2 PF12813.7 KNE02471.1 - 0.011 15.3 0.0 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 XPG domain containing Tex_N PF09371.10 KNE02471.1 - 0.049 13.3 1.8 0.077 12.7 0.2 2.0 2 0 0 2 2 2 0 Tex-like protein N-terminal domain TEA PF01285.18 KNE02472.1 - 1.1e-08 35.0 0.6 2.2e-08 34.0 0.6 1.6 1 0 0 1 1 1 1 TEA/ATTS domain Pkinase PF00069.25 KNE02473.1 - 6.9e-63 212.5 0.0 8.4e-63 212.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE02473.1 - 4.7e-39 134.2 0.0 6.5e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNE02473.1 - 6.7e-05 21.8 0.0 9.1e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KNE02473.1 - 8.1e-05 22.1 0.0 0.00027 20.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KNE02473.1 - 0.012 14.6 0.0 0.11 11.4 0.0 2.1 1 1 0 1 1 1 0 Haspin like kinase domain RPAP1_C PF08620.10 KNE02474.1 - 1.3e-30 105.3 0.1 2.6e-30 104.3 0.1 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KNE02474.1 - 1.2e-14 53.8 3.4 2.5e-14 52.7 3.4 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal DUF5529 PF17669.1 KNE02474.1 - 0.024 14.7 1.1 0.042 13.9 1.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5529) mRNA_decap_C PF16741.5 KNE02474.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus EMC1_C PF07774.13 KNE02476.1 - 1.5e-52 178.4 0.1 3.5e-52 177.2 0.1 1.6 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal Zn_clus PF00172.18 KNE02477.1 - 3.7e-05 23.8 12.1 7.7e-05 22.7 12.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2770 PF10968.8 KNE02477.1 - 0.074 13.0 0.1 0.23 11.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2770) Rpr2 PF04032.16 KNE02480.1 - 2.8e-09 37.1 0.7 2.8e-09 37.1 0.7 1.7 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Pex24p PF06398.11 KNE02481.1 - 4.2e-53 180.6 1.4 5.2e-53 180.3 1.4 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin SIR2 PF02146.17 KNE02482.1 - 4.1e-37 127.8 0.0 3.2e-20 72.8 0.0 2.4 2 0 0 2 2 2 2 Sir2 family BLOC1_2 PF10046.9 KNE02482.1 - 0.0079 16.5 1.2 0.032 14.5 0.1 2.5 3 0 0 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Pkinase PF00069.25 KNE02483.1 - 1e-74 251.3 0.0 1.6e-74 250.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain AdenylateSensor PF16579.5 KNE02483.1 - 4.5e-55 185.1 0.0 1.1e-54 183.9 0.0 1.7 1 0 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase Pkinase_Tyr PF07714.17 KNE02483.1 - 4.8e-38 130.9 0.0 9.7e-38 129.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.11 KNE02483.1 - 6.7e-22 77.3 3.2 1.3e-21 76.4 1.5 2.2 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KNE02483.1 - 9.2e-08 31.7 0.0 2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KNE02483.1 - 0.00012 21.8 0.1 0.00022 20.9 0.1 1.4 1 0 0 1 1 1 1 RIO1 family YukC PF10140.9 KNE02483.1 - 0.0011 17.9 0.2 0.0011 17.9 0.2 1.7 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukC Haspin_kinase PF12330.8 KNE02483.1 - 0.0028 16.7 0.1 0.0028 16.7 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KNE02483.1 - 0.025 13.9 0.1 0.048 13.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2443 PF10398.9 KNE02483.1 - 0.085 12.9 0.3 0.27 11.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) APH PF01636.23 KNE02483.1 - 0.098 12.6 0.8 0.24 11.3 0.6 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family PWI PF01480.17 KNE02484.1 - 1.7e-15 57.1 0.0 3.2e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 PWI domain YTH PF04146.15 KNE02485.1 - 2.3e-39 135.0 2.0 4.5e-39 134.1 2.0 1.5 1 0 0 1 1 1 1 YT521-B-like domain Svf1 PF08622.10 KNE02485.1 - 0.1 12.7 0.4 0.17 11.9 0.4 1.3 1 0 0 1 1 1 0 Svf1-like N-terminal lipocalin domain COQ7 PF03232.13 KNE02486.1 - 9.6e-75 250.1 0.1 1.2e-74 249.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KNE02486.1 - 0.0057 17.1 0.0 0.02 15.3 0.0 1.8 2 0 0 2 2 2 1 Rubrerythrin Nuf2 PF03800.14 KNE02487.1 - 1.2e-43 148.5 2.2 4.2e-43 146.8 2.2 2.0 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 KNE02487.1 - 6e-08 32.8 18.7 6e-08 32.8 18.7 3.9 2 2 1 3 3 3 1 Designed helical repeat protein 10 domain Baculo_PEP_C PF04513.12 KNE02487.1 - 0.032 14.3 26.5 0.3 11.1 4.3 4.2 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF357 PF04010.13 KNE02487.1 - 0.099 12.7 2.2 21 5.2 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF357) DUF1676 PF07898.13 KNE02487.1 - 0.33 11.0 5.5 5.2 7.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) TAF8_C PF10406.9 KNE02487.1 - 0.72 10.5 3.5 0.94 10.1 0.2 3.0 3 1 0 3 3 3 0 Transcription factor TFIID complex subunit 8 C-term CENP-F_leu_zip PF10473.9 KNE02487.1 - 0.92 9.5 45.8 0.086 12.9 8.7 3.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 KNE02487.1 - 6.5 6.0 48.5 0.042 13.2 13.1 3.9 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 KNE02487.1 - 9.2 6.0 45.9 1.4 8.7 11.9 3.7 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH MFS_1 PF07690.16 KNE02488.1 - 1.9e-42 145.5 55.8 8.3e-41 140.1 56.9 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KNE02488.1 - 5.7e-18 64.7 14.3 5.7e-18 64.7 14.3 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KNE02488.1 - 3.4e-11 42.7 15.7 3.4e-11 42.7 15.7 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter Git3 PF11710.8 KNE02489.1 - 6.3e-78 261.2 18.8 6.3e-78 261.2 18.8 1.5 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KNE02489.1 - 9e-35 118.6 1.7 2.6e-34 117.1 1.7 1.9 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 KNE02489.1 - 6.1 5.9 19.5 0.35 10.0 11.7 2.1 2 0 0 2 2 2 0 Slime mold cyclic AMP receptor AA_permease PF00324.21 KNE02491.1 - 3.2e-108 362.4 34.1 3.7e-108 362.2 34.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KNE02491.1 - 2.8e-25 89.0 37.7 4.2e-25 88.5 37.7 1.2 1 0 0 1 1 1 1 Amino acid permease Suppressor_APC PF11414.8 KNE02491.1 - 0.14 12.3 0.3 0.25 11.4 0.3 1.3 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein UPF0640 PF15114.6 KNE02491.1 - 0.25 11.2 5.4 0.66 9.8 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0640 AMPK1_CBM PF16561.5 KNE02493.1 - 1.4e-29 102.1 0.2 2.6e-29 101.3 0.2 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KNE02493.1 - 6.1e-27 93.7 3.0 1.9e-26 92.1 3.0 1.9 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain STE2 PF02116.15 KNE02495.1 - 4.8e-69 232.8 25.6 6.2e-69 232.4 25.6 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF347 PF03988.12 KNE02495.1 - 6.9 6.9 8.9 0.95 9.7 0.1 3.2 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) Y_phosphatase2 PF03162.13 KNE02496.1 - 3.9e-58 195.7 0.1 5.7e-58 195.1 0.1 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KNE02496.1 - 1.8e-06 28.1 0.0 3.9e-06 27.0 0.0 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KNE02496.1 - 0.0024 17.5 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KNE02496.1 - 0.0037 17.1 0.0 0.0056 16.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Aim19 PF10315.9 KNE02497.1 - 8.2e-41 138.9 1.3 9.5e-41 138.7 1.3 1.0 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Histone PF00125.24 KNE02498.1 - 6.5e-51 172.1 2.4 9.6e-51 171.6 2.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KNE02498.1 - 7.3e-06 26.3 0.0 1.4e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KNE02498.1 - 0.00011 22.2 0.6 0.0002 21.4 0.1 1.7 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KNE02498.1 - 0.00013 22.5 1.6 0.00018 22.1 1.6 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KNE02498.1 - 0.0069 16.7 0.1 0.019 15.3 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2102 PF09875.9 KNE02498.1 - 0.0097 15.6 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2102) TFIID-31kDa PF02291.15 KNE02498.1 - 0.051 13.6 0.4 0.092 12.8 0.1 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KNE02499.1 - 9.1e-10 38.6 0.1 1.1e-09 38.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KNE02499.1 - 1.7e-05 24.9 0.1 2.4e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KNE02499.1 - 3.8e-05 23.9 0.1 6.5e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KNE02499.1 - 8.4e-05 22.9 0.1 9.8e-05 22.7 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KNE02499.1 - 8.8e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KNE02499.1 - 0.0026 17.8 0.0 0.0031 17.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KNE02499.1 - 0.0047 16.9 0.0 0.0056 16.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated UPF0137 PF03677.13 KNE02499.1 - 0.019 14.8 0.2 0.023 14.5 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TAFII28 PF04719.14 KNE02499.1 - 0.051 13.7 0.0 0.06 13.4 0.0 1.1 1 0 0 1 1 1 0 hTAFII28-like protein conserved region TFIID_20kDa PF03847.13 KNE02499.1 - 0.069 13.7 0.1 0.13 12.8 0.1 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID subunit A Glyco_transf_15 PF01793.16 KNE02500.1 - 1.5e-88 297.2 13.6 3.9e-57 194.0 3.6 2.2 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase Sds3 PF08598.11 KNE02502.1 - 2.3e-59 201.0 16.4 1.1e-58 198.9 16.4 1.9 1 1 0 1 1 1 1 Sds3-like Acetyltransf_1 PF00583.25 KNE02503.1 - 2.1e-05 24.7 0.1 7.3e-05 23.0 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KNE02503.1 - 0.00015 22.5 0.0 0.00019 22.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KNE02503.1 - 0.0015 18.7 0.1 0.0023 18.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-H2C2 PF09337.10 KNE02504.1 - 2.4e-12 46.8 1.5 5.1e-12 45.8 1.5 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 KNE02504.1 - 2.8e-10 40.2 0.3 5.2e-10 39.3 0.3 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 KNE02504.1 - 1.3e-05 25.4 0.0 2.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KNE02504.1 - 0.0025 18.2 0.0 0.028 14.8 0.0 2.7 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KNE02504.1 - 0.15 12.7 0.0 0.31 11.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CPSase_L_D2 PF02786.17 KNE02505.1 - 1e-115 384.6 0.6 5.1e-84 281.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 KNE02505.1 - 2.6e-47 159.8 0.0 5.8e-47 158.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 KNE02505.1 - 7.3e-46 155.8 0.0 1.9e-45 154.5 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 KNE02505.1 - 4.3e-45 153.8 0.0 9.9e-45 152.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 KNE02505.1 - 6.5e-39 133.0 0.0 1.5e-38 131.9 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KNE02505.1 - 2.2e-29 102.6 0.1 3.2e-28 98.8 0.0 2.9 3 0 0 3 3 3 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 KNE02505.1 - 5.4e-20 71.4 0.0 2e-19 69.6 0.0 2.1 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 KNE02505.1 - 4.1e-18 65.7 1.5 6.7e-10 38.8 0.3 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KNE02505.1 - 1.3e-15 57.4 0.2 1.6e-08 34.3 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KNE02505.1 - 4.8e-10 39.3 0.0 7.4e-05 22.5 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 KNE02505.1 - 6.1e-07 29.6 0.9 0.0067 16.5 0.1 2.9 3 0 0 3 3 3 2 ATP-grasp domain DJ-1_PfpI PF01965.24 KNE02505.1 - 0.00025 20.9 0.7 0.023 14.5 0.0 4.1 5 0 0 5 5 5 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 KNE02505.1 - 0.00047 20.0 0.3 0.034 13.9 0.3 2.9 1 1 0 1 1 1 1 Peptidase C26 GARS_A PF01071.19 KNE02505.1 - 0.041 13.7 0.5 0.69 9.7 0.1 2.7 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 KNE02505.1 - 0.14 11.6 0.2 12 5.3 0.1 2.4 2 0 0 2 2 2 0 ATP-grasp domain MFS_1 PF07690.16 KNE02508.1 - 5.4e-45 153.9 22.8 5.4e-45 153.9 22.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KNE02508.1 - 2e-10 40.1 9.2 2e-10 40.1 9.2 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter TrkH PF02386.16 KNE02509.1 - 3e-158 527.4 4.0 3e-158 527.4 4.0 2.0 2 0 0 2 2 2 1 Cation transport protein PI3K_1B_p101 PF10486.9 KNE02509.1 - 0.31 8.8 7.3 0.52 8.0 7.3 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CDC45 PF02724.14 KNE02509.1 - 2.6 6.2 21.5 4.8 5.4 21.5 1.4 1 0 0 1 1 1 0 CDC45-like protein Brix PF04427.18 KNE02510.1 - 6.1e-30 104.8 0.6 8e-30 104.4 0.6 1.2 1 0 0 1 1 1 1 Brix domain RNA_pol_Rpb2_5 PF04567.17 KNE02511.1 - 0.17 12.5 0.0 0.18 12.4 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 SRP-alpha_N PF04086.13 KNE02512.1 - 0.21 11.5 8.7 0.23 11.3 8.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RICTOR_N PF14664.6 KNE02513.1 - 3.8e-91 305.9 2.8 7.3e-91 304.9 2.8 1.5 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 KNE02513.1 - 3.5e-24 84.6 3.7 2.5e-22 78.6 0.1 4.8 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 KNE02513.1 - 5.4e-23 81.0 0.8 3.7e-21 75.1 0.1 3.7 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.6 KNE02513.1 - 8.8e-13 48.6 0.3 7e-11 42.5 0.0 3.9 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Cnd1 PF12717.7 KNE02513.1 - 0.014 15.4 1.1 0.47 10.5 0.1 3.1 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF5624 PF18538.1 KNE02514.1 - 0.028 14.5 0.3 0.046 13.8 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) DUF3388 PF11868.8 KNE02514.1 - 0.056 12.8 0.5 0.15 11.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3388) LptF_LptG PF03739.14 KNE02514.1 - 0.54 9.0 1.7 0.66 8.8 1.7 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG ASF1_hist_chap PF04729.13 KNE02515.1 - 2.9e-71 238.4 0.0 4.5e-71 237.8 0.0 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone TFIIF_alpha PF05793.12 KNE02515.1 - 0.0027 16.4 20.8 0.003 16.2 20.8 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TLP-20 PF06088.11 KNE02515.1 - 0.46 10.4 8.1 0.73 9.7 8.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Spore_coat_CotO PF14153.6 KNE02515.1 - 0.83 9.5 14.7 1.2 9.0 14.7 1.3 1 0 0 1 1 1 0 Spore coat protein CotO PTPRCAP PF15713.5 KNE02515.1 - 2 8.7 20.3 2.8 8.2 20.3 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Merozoite_SPAM PF07133.11 KNE02515.1 - 2.9 7.8 34.2 3.8 7.5 34.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DNA_pol_phi PF04931.13 KNE02515.1 - 5.4 5.0 27.1 6.7 4.7 27.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KNE02515.1 - 6.6 4.8 24.4 7.1 4.7 24.4 1.0 1 0 0 1 1 1 0 Nop14-like family Mem_trans PF03547.18 KNE02520.1 - 9.8e-28 96.6 6.9 4.4e-27 94.5 6.9 1.8 1 1 0 1 1 1 1 Membrane transport protein K-cyclin_vir_C PF09080.10 KNE02520.1 - 0.12 12.9 0.3 0.2 12.1 0.3 1.3 1 0 0 1 1 1 0 K cyclin, C terminal Ras PF00071.22 KNE02522.1 - 3e-48 163.5 0.7 3.5e-48 163.3 0.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNE02522.1 - 7.7e-16 58.4 0.0 1.2e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KNE02522.1 - 4.5e-06 26.3 0.1 6.6e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KNE02522.1 - 5.3e-05 22.7 0.1 6.2e-05 22.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KNE02522.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 KNE02522.1 - 0.014 14.8 0.0 0.021 14.3 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KNE02522.1 - 0.077 12.9 0.3 0.18 11.7 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase DAO PF01266.24 KNE02523.1 - 5.4e-10 39.4 0.0 5.9e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase GDA1_CD39 PF01150.17 KNE02524.1 - 1.2e-79 268.0 0.0 1.5e-78 264.4 0.0 2.3 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family UCH PF00443.29 KNE02525.1 - 5.1e-44 150.7 0.0 1.1e-43 149.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KNE02525.1 - 4.6e-05 23.2 0.0 0.00098 18.8 0.0 2.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase OppC_N PF12911.7 KNE02525.1 - 2.4 8.2 3.8 39 4.3 0.2 2.5 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C RRM_1 PF00076.22 KNE02527.1 - 2.5e-49 165.0 0.6 9.3e-17 60.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KNE02527.1 - 3.7e-10 39.5 0.0 1.4e-05 24.8 0.0 3.8 3 1 1 4 4 4 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KNE02527.1 - 5.9e-06 25.9 0.0 0.0015 18.1 0.1 2.9 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KNE02527.1 - 0.034 14.3 0.0 1.8 8.7 0.0 2.9 2 1 0 2 2 2 0 RNA recognition motif PHM7_cyt PF14703.6 KNE02527.1 - 0.092 13.0 0.0 15 5.7 0.0 3.0 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 KNE02527.1 - 0.14 12.2 0.0 3.8 7.6 0.0 2.6 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Met_10 PF02475.16 KNE02528.1 - 4.2e-11 43.0 0.0 2.9e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 Met-10+ like-protein MTS PF05175.14 KNE02528.1 - 0.028 13.9 0.0 0.078 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain zf-C2H2 PF00096.26 KNE02529.1 - 1.9e-14 53.2 16.1 1.3e-06 28.5 3.8 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KNE02529.1 - 3.6e-13 49.3 12.2 1.2e-07 31.9 0.5 4.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KNE02529.1 - 4.3e-09 36.4 11.9 0.0011 19.6 2.4 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KNE02529.1 - 2.9e-06 27.5 7.7 0.00056 20.2 0.5 4.4 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KNE02529.1 - 3.3e-06 26.9 5.8 0.0016 18.4 0.8 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KNE02529.1 - 0.00012 22.3 9.9 0.0095 16.2 0.4 3.9 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KNE02529.1 - 0.083 13.0 1.1 0.21 11.7 1.1 1.7 1 0 0 1 1 1 0 Zinc ribbon domain zf-C2HE PF16278.5 KNE02529.1 - 0.089 13.3 6.4 2 8.9 1.2 3.5 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 KNE02529.1 - 0.13 12.0 7.0 0.83 9.5 0.1 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KNE02529.1 - 0.2 11.6 0.2 0.2 11.6 0.2 2.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zn_ribbon_recom PF13408.6 KNE02529.1 - 0.32 11.5 4.0 0.12 12.9 0.8 1.9 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain FYVE PF01363.21 KNE02529.1 - 0.34 11.1 5.9 0.85 9.8 5.9 1.7 1 1 0 1 1 1 0 FYVE zinc finger zf-BED PF02892.15 KNE02529.1 - 0.84 9.7 4.2 1.1e+02 2.9 4.2 3.1 1 1 0 1 1 1 0 BED zinc finger Bac_surface_Ag PF01103.23 KNE02531.1 - 2.3e-43 148.9 6.1 2.9e-43 148.6 6.1 1.1 1 0 0 1 1 1 1 Surface antigen DFP PF04127.15 KNE02532.1 - 6.2e-19 68.5 0.0 5.3e-11 42.7 0.0 2.6 2 1 1 3 3 3 2 DNA / pantothenate metabolism flavoprotein Pro_isomerase PF00160.21 KNE02533.1 - 8.9e-29 100.8 0.1 9.8e-29 100.7 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cyclin_N PF00134.23 KNE02534.1 - 1.1e-12 47.9 0.9 2.4e-12 46.7 0.9 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KNE02534.1 - 0.013 15.8 0.0 0.036 14.5 0.0 1.8 1 0 0 1 1 1 0 Cyclin C-terminal domain TRAM_LAG1_CLN8 PF03798.16 KNE02535.1 - 1.3e-42 145.8 27.3 1.3e-42 145.8 27.3 2.1 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KNE02535.1 - 9e-16 57.3 1.7 9e-16 57.3 1.7 2.1 2 0 0 2 2 2 1 TRAM1-like protein GP67 PF17634.2 KNE02535.1 - 0.041 14.3 5.9 3.2 8.2 7.0 2.3 2 0 0 2 2 2 0 Gene product 67 Aa_trans PF01490.18 KNE02536.1 - 6.8e-90 301.7 32.3 8.6e-90 301.4 32.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CENP-X PF09415.10 KNE02537.1 - 3.8e-18 65.6 0.5 3.4e-17 62.5 0.5 2.0 1 1 0 1 1 1 1 CENP-S associating Centromere protein X Ecm29 PF13001.7 KNE02537.1 - 0.023 13.4 0.0 0.028 13.1 0.0 1.1 1 0 0 1 1 1 0 Proteasome stabiliser TAFII28 PF04719.14 KNE02537.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Dynactin_p62 PF05502.13 KNE02538.1 - 5.2e-07 28.8 10.7 6.1e-07 28.6 5.6 2.2 1 1 1 2 2 2 2 Dynactin p62 family Elf1 PF05129.13 KNE02538.1 - 0.011 15.8 1.9 0.71 10.0 1.0 2.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-C3HC PF07967.13 KNE02538.1 - 0.04 13.9 1.1 0.2 11.7 0.0 2.3 2 0 0 2 2 2 0 C3HC zinc finger-like Gly-zipper_Omp PF13488.6 KNE02539.1 - 0.0024 17.8 18.8 0.0024 17.8 18.8 3.8 3 0 0 3 3 3 1 Glycine zipper NPC1_N PF16414.5 KNE02540.1 - 5.6e-74 248.8 9.5 9.8e-74 248.0 9.5 1.4 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 KNE02540.1 - 1.7e-67 228.2 23.2 4.3e-64 217.0 20.7 4.3 3 1 0 3 3 3 2 Patched family Sterol-sensing PF12349.8 KNE02540.1 - 6.7e-49 165.7 8.0 6.7e-49 165.7 8.0 3.3 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 KNE02540.1 - 0.00035 18.4 11.0 0.00065 17.5 11.0 1.4 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family dCMP_cyt_deam_1 PF00383.23 KNE02541.1 - 1.9e-27 95.1 1.8 2.9e-27 94.5 1.8 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KNE02541.1 - 2.3e-13 50.1 0.3 4.2e-13 49.2 0.3 1.4 1 0 0 1 1 1 1 MafB19-like deaminase Dynamin_N PF00350.23 KNE02541.1 - 0.098 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Dynamin family FAA_hydrolase PF01557.18 KNE02542.1 - 6e-51 173.2 0.0 7.4e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DCR PF14047.6 KNE02543.1 - 0.077 13.2 0.0 0.092 13.0 0.0 1.2 1 0 0 1 1 1 0 Dppa2/4 conserved region FTR1 PF03239.14 KNE02544.1 - 6e-97 324.5 8.3 7.6e-97 324.2 8.3 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family Glyco_hydro81C PF17652.1 KNE02546.1 - 1.4e-146 488.2 6.2 1.9e-146 487.8 6.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KNE02546.1 - 9.3e-90 301.1 3.4 9.3e-90 301.1 3.4 1.5 1 1 1 2 2 2 1 Glycosyl hydrolase family 81 N-terminal domain MFS_1 PF07690.16 KNE02552.1 - 4.4e-11 42.3 43.4 8.1e-07 28.3 23.0 3.9 2 2 1 3 3 3 3 Major Facilitator Superfamily DUF2530 PF10745.9 KNE02552.1 - 0.078 13.2 0.1 0.078 13.2 0.1 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2530) Bromodomain PF00439.25 KNE02553.1 - 4e-13 49.3 0.3 1.8e-12 47.1 0.3 2.2 1 0 0 1 1 1 1 Bromodomain GST_C_3 PF14497.6 KNE02553.1 - 0.078 13.2 0.3 2.6 8.3 0.1 2.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain SEA PF01390.20 KNE02553.1 - 0.29 11.2 4.8 1.1 9.4 0.1 3.3 3 0 0 3 3 3 0 SEA domain LAMTOR PF15454.6 KNE02553.1 - 5.2 7.8 13.5 5.4 7.7 4.9 3.4 3 0 0 3 3 3 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator zf-Tim10_DDP PF02953.15 KNE02554.1 - 8.8e-22 76.5 6.4 1.2e-21 76.1 6.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Hormone_recep PF00104.30 KNE02554.1 - 0.0093 15.6 2.8 0.01 15.4 2.8 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Phasin_2 PF09361.10 KNE02554.1 - 0.013 15.8 0.0 0.14 12.5 0.0 1.9 1 1 1 2 2 2 0 Phasin protein tRNA-synt_2 PF00152.20 KNE02555.1 - 2.7e-80 269.8 0.0 3.4e-80 269.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KNE02555.1 - 6.8e-06 26.0 0.0 1.8e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.25 KNE02555.1 - 0.076 13.0 0.0 0.22 11.5 0.0 1.8 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) PHP PF02811.19 KNE02557.1 - 9.6e-14 52.0 0.1 1.6e-13 51.3 0.1 1.3 1 0 0 1 1 1 1 PHP domain RNase_P_p30 PF01876.16 KNE02557.1 - 0.11 11.9 0.0 9.4 5.6 0.0 2.2 2 0 0 2 2 2 0 RNase P subunit p30 ProRS-C_1 PF09180.11 KNE02558.1 - 1.2e-23 83.0 0.1 2.7e-23 82.0 0.1 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 KNE02558.1 - 3.9e-19 69.3 0.0 8.9e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KNE02558.1 - 8.1e-19 67.6 0.3 2.4e-18 66.0 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA_edit PF04073.15 KNE02558.1 - 1.5e-06 28.3 1.3 2.6e-06 27.5 1.3 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_2 PF00152.20 KNE02559.1 - 5.5e-92 308.2 0.0 8.2e-92 307.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KNE02559.1 - 3e-12 46.3 0.1 7e-12 45.2 0.1 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 KNE02559.1 - 0.0022 18.2 0.0 0.005 17.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ins134_P3_kin PF05770.11 KNE02559.1 - 0.026 14.1 0.0 0.058 12.9 0.0 1.6 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain CDRT4 PF15213.6 KNE02559.1 - 0.14 12.7 0.5 0.24 12.0 0.5 1.3 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein Lyase_1 PF00206.20 KNE02560.1 - 1.5e-101 339.9 0.0 2.4e-101 339.2 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KNE02560.1 - 1.2e-22 80.5 0.0 2.7e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal MotA_ExbB PF01618.16 KNE02560.1 - 0.13 12.0 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family Chromadorea_ALT PF05535.12 KNE02563.1 - 0.024 14.8 0.2 0.29 11.3 0.9 2.4 2 0 0 2 2 2 0 Chromadorea ALT protein NUC153 PF08159.12 KNE02564.1 - 1.1e-13 50.7 0.8 2.8e-13 49.4 0.8 1.8 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KNE02564.1 - 0.009 16.8 0.0 61 4.7 0.0 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNE02564.1 - 0.063 13.6 0.0 1.1 9.6 0.0 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Isy1 PF06246.12 KNE02565.1 - 4.4e-49 167.4 5.3 3.6e-47 161.1 1.8 2.0 1 1 0 2 2 2 2 Isy1-like splicing family Isochorismatase PF00857.20 KNE02566.1 - 9e-23 81.3 3.6 2.1e-22 80.2 3.6 1.6 1 1 0 1 1 1 1 Isochorismatase family Gly_transf_sug PF04488.15 KNE02567.1 - 5.1e-16 59.1 0.7 5.7e-15 55.7 0.1 2.3 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KNE02567.1 - 0.009 15.4 1.2 0.017 14.5 1.2 1.5 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Cloacin_immun PF03513.14 KNE02567.1 - 0.084 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Cloacin immunity protein DEAD PF00270.29 KNE02568.1 - 3.7e-47 160.3 0.0 8.9e-47 159.1 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNE02568.1 - 5.2e-31 107.3 0.0 1.7e-30 105.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNE02568.1 - 0.00037 20.6 0.0 0.00067 19.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NAD_kinase PF01513.21 KNE02570.1 - 5.7e-81 271.9 0.0 7.9e-81 271.4 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KNE02570.1 - 0.00033 20.2 0.0 0.00099 18.7 0.0 1.8 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain GDA1_CD39 PF01150.17 KNE02571.1 - 2.3e-116 389.0 0.0 2.9e-116 388.6 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family CRF1 PF10380.9 KNE02572.1 - 5.8e-28 97.5 1.6 5.8e-28 97.5 1.6 4.8 5 1 0 5 5 5 2 Transcription factor CRF1 PHD PF00628.29 KNE02573.1 - 2.1e-08 33.9 7.8 6.1e-08 32.4 7.7 1.9 1 1 1 2 2 2 1 PHD-finger TFIIS_M PF07500.14 KNE02573.1 - 3.2e-08 34.0 0.5 6.8e-08 33.0 0.5 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 KNE02573.1 - 3.3e-08 33.6 0.0 8.1e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 SPOC domain PHD_2 PF13831.6 KNE02573.1 - 0.0011 18.4 1.4 0.0011 18.4 1.4 1.8 2 0 0 2 2 2 1 PHD-finger PHD_4 PF16866.5 KNE02573.1 - 0.24 11.5 6.0 0.63 10.2 6.0 1.7 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 KNE02573.1 - 0.37 10.7 2.5 0.25 11.3 0.2 1.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KNE02573.1 - 1.3 9.4 4.8 4 7.8 1.6 2.5 2 0 0 2 2 2 0 C1 domain Rad9_Rad53_bind PF08605.10 KNE02574.1 - 1.1e-22 80.5 0.2 2.4e-22 79.5 0.2 1.6 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.26 KNE02574.1 - 9.9e-10 38.7 0.9 4.2e-09 36.7 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KNE02574.1 - 0.00023 21.5 0.0 0.00023 21.5 0.0 3.0 3 1 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain Pro_dh PF01619.18 KNE02575.1 - 1.7e-63 215.0 0.3 2.1e-63 214.7 0.3 1.0 1 0 0 1 1 1 1 Proline dehydrogenase SLS PF14611.6 KNE02578.1 - 3.4e-25 89.2 2.9 3.4e-25 89.2 2.9 2.3 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator Secretin_N PF03958.17 KNE02578.1 - 0.068 13.6 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain FGF PF00167.18 KNE02578.1 - 0.11 12.6 0.2 0.48 10.5 0.0 2.1 2 0 0 2 2 2 0 Fibroblast growth factor UPF0225 PF17775.1 KNE02578.1 - 0.16 12.8 0.2 0.43 11.4 0.2 1.7 1 0 0 1 1 1 0 UPF0225 domain TFA2_Winged_2 PF18121.1 KNE02579.1 - 0.12 12.1 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 LapA_dom PF06305.11 KNE02579.1 - 0.2 11.5 0.3 0.61 9.9 0.3 1.8 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain ABC1 PF03109.16 KNE02580.1 - 1.2e-26 93.2 1.2 3.1e-26 91.9 0.6 2.1 2 0 0 2 2 2 1 ABC1 family Pkinase PF00069.25 KNE02580.1 - 0.0074 15.7 0.5 0.05 13.0 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 KNE02580.1 - 0.023 14.6 0.1 0.14 12.1 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Rep_Org_C PF06926.11 KNE02580.1 - 0.13 12.6 1.4 0.83 10.0 0.2 2.8 2 1 1 3 3 3 0 Putative replisome organiser protein C-terminus WD40 PF00400.32 KNE02581.1 - 5.2e-43 144.2 15.2 1.4e-05 25.7 0.1 11.4 11 0 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.11 KNE02581.1 - 3.7e-40 137.1 4.5 6e-40 136.4 4.5 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 KNE02581.1 - 9.3e-20 70.7 4.3 4.2e-05 23.7 0.0 8.0 5 2 3 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KNE02581.1 - 1.2e-06 28.1 0.1 0.0045 16.3 0.0 4.6 4 1 1 5 5 5 1 WD40-like domain eIF2A PF08662.11 KNE02581.1 - 2.3e-05 24.4 0.2 2 8.3 0.0 5.0 2 2 3 5 5 5 1 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.9 KNE02581.1 - 0.00083 19.2 0.3 0.0048 16.7 0.1 2.4 3 0 0 3 3 3 1 Lipoprotein LpqB beta-propeller domain Hira PF07569.11 KNE02581.1 - 0.009 15.8 3.4 15 5.3 0.1 4.8 3 2 1 5 5 5 1 TUP1-like enhancer of split Nup160 PF11715.8 KNE02581.1 - 0.016 13.9 6.3 10 4.6 0.0 4.9 4 2 0 5 5 5 0 Nucleoporin Nup120/160 HmuY PF14064.6 KNE02581.1 - 0.018 15.3 0.1 0.1 12.8 0.0 2.1 1 1 0 2 2 2 0 HmuY protein PQQ_2 PF13360.6 KNE02581.1 - 0.037 13.6 5.1 0.075 12.6 1.0 3.1 3 1 0 3 3 3 0 PQQ-like domain Nucleoporin_N PF08801.11 KNE02581.1 - 0.17 10.6 0.0 3 6.5 0.0 2.8 2 1 0 2 2 2 0 Nup133 N terminal like HA70_C PF17993.1 KNE02582.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Haemagglutinin 70 C-terminal domain MSC PF09402.10 KNE02589.1 - 9.7e-51 173.2 0.1 1.2e-50 172.9 0.1 1.0 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain Telomere_reg-2 PF10193.9 KNE02589.1 - 0.11 13.0 0.1 0.17 12.3 0.1 1.2 1 0 0 1 1 1 0 Telomere length regulation protein MSC PF09402.10 KNE02590.1 - 5e-32 111.7 3.7 5.4e-32 111.6 3.7 1.0 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain DUF2500 PF10694.9 KNE02590.1 - 0.078 13.5 1.5 0.095 13.2 0.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2500) Holin_BhlA PF10960.8 KNE02590.1 - 0.088 12.8 0.2 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 BhlA holin family Peptidase_S49_N PF08496.10 KNE02590.1 - 0.11 12.5 1.9 0.47 10.5 1.9 1.8 1 1 0 1 1 1 0 Peptidase family S49 N-terminal RWD PF05773.22 KNE02591.1 - 2.3e-21 76.2 2.9 2.3e-21 76.2 2.9 2.0 2 0 0 2 2 2 1 RWD domain DFRP_C PF16543.5 KNE02591.1 - 1.3e-07 32.0 5.6 1.3e-07 32.0 5.6 1.9 2 1 0 2 2 2 1 DRG Family Regulatory Proteins, Tma46 SH3_1 PF00018.28 KNE02593.1 - 1.2e-09 37.6 0.1 2.9e-09 36.4 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KNE02593.1 - 6.9e-08 32.2 0.3 1.4e-07 31.2 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KNE02593.1 - 8.6e-06 25.3 0.1 1.5e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain GcpE PF04551.14 KNE02597.1 - 0.23 10.5 0.0 0.23 10.5 0.0 1.0 1 0 0 1 1 1 0 GcpE protein Pro_isomerase PF00160.21 KNE02599.1 - 7.9e-47 159.5 0.1 8.9e-47 159.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.6 KNE02599.1 - 0.055 13.5 0.0 0.082 13.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Redoxin PF08534.10 KNE02600.1 - 9e-25 87.1 0.0 9.8e-25 87.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KNE02600.1 - 0.013 15.4 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Avl9 PF09794.9 KNE02601.1 - 1.8e-119 398.8 8.5 1.8e-119 398.8 8.5 1.5 2 0 0 2 2 2 1 Transport protein Avl9 DUF2347 PF09804.9 KNE02601.1 - 6.2e-09 35.8 2.1 1.1e-08 35.0 2.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DENN PF02141.21 KNE02601.1 - 4.5e-05 23.5 3.8 4.5e-05 23.5 3.8 1.7 2 0 0 2 2 2 1 DENN (AEX-3) domain SPA PF08616.10 KNE02601.1 - 0.28 11.1 8.4 1 9.3 0.1 3.5 4 0 0 4 4 4 0 Stabilization of polarity axis WD40 PF00400.32 KNE02602.1 - 5.9e-05 23.8 1.1 0.11 13.4 0.6 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat ABC_membrane PF00664.23 KNE02603.1 - 3.9e-83 279.3 30.1 1.2e-43 149.7 15.6 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KNE02603.1 - 2.4e-51 173.9 0.2 5.5e-30 104.7 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KNE02603.1 - 9.2e-10 38.3 4.5 8.1e-05 22.2 0.8 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KNE02603.1 - 3.3e-06 27.2 0.2 0.082 13.0 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNE02603.1 - 0.00027 20.9 0.1 0.37 10.7 0.3 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KNE02603.1 - 0.00031 20.4 0.5 0.99 9.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 KNE02603.1 - 0.0049 16.6 2.3 1.4 8.6 0.2 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KNE02603.1 - 0.0052 16.6 0.5 2.3 7.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system UPF0093 PF03653.13 KNE02603.1 - 0.011 16.0 0.3 0.05 13.8 0.3 2.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0093) AAA_16 PF13191.6 KNE02603.1 - 0.017 15.5 1.2 2.8 8.3 0.0 2.9 3 0 0 3 3 2 0 AAA ATPase domain AAA_23 PF13476.6 KNE02603.1 - 0.019 15.5 3.7 4.1 7.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 KNE02603.1 - 0.022 14.8 2.2 2.3 8.3 0.0 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_7 PF12775.7 KNE02603.1 - 0.043 13.3 0.1 2.5 7.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 KNE02603.1 - 0.058 13.4 1.5 1.1 9.3 0.1 2.5 2 0 0 2 2 2 0 Dynamin family DUF3671 PF12420.8 KNE02603.1 - 0.15 12.2 4.3 0.95 9.6 0.7 3.3 2 1 0 2 2 2 0 Protein of unknown function AAA_22 PF13401.6 KNE02603.1 - 0.15 12.3 2.0 16 5.7 0.1 3.1 3 1 0 3 3 2 0 AAA domain AAA_30 PF13604.6 KNE02603.1 - 0.15 11.7 0.3 16 5.1 0.0 2.8 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 KNE02603.1 - 0.17 12.1 0.2 32 4.8 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Sec1 PF00995.23 KNE02605.1 - 8.7e-88 296.0 0.9 1.1e-87 295.7 0.9 1.0 1 0 0 1 1 1 1 Sec1 family UAA PF08449.11 KNE02607.1 - 1.5e-12 47.4 9.8 1.7e-12 47.1 9.8 1.0 1 0 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 KNE02607.1 - 3.9e-09 36.2 5.2 2.4e-07 30.3 5.2 2.2 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport TPT PF03151.16 KNE02607.1 - 4.6e-09 36.0 8.7 6.2e-09 35.6 8.7 1.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KNE02607.1 - 3.1e-05 24.2 29.9 0.00029 21.0 18.9 2.3 2 0 0 2 2 2 2 EamA-like transporter family Herpes_LMP1 PF05297.11 KNE02607.1 - 0.0053 16.0 6.4 0.0053 16.0 6.4 1.8 1 1 0 1 1 1 1 Herpesvirus latent membrane protein 1 (LMP1) DUF1129 PF06570.11 KNE02607.1 - 0.021 14.3 1.1 0.021 14.3 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Asp PF00026.23 KNE02608.1 - 9e-18 64.7 0.0 1.9e-17 63.7 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease DGF-1_C PF11040.8 KNE02609.1 - 0.12 12.4 0.0 0.12 12.4 0.0 1.0 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Response_reg PF00072.24 KNE02610.1 - 8.2e-27 93.6 0.0 1.6e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KNE02610.1 - 1.5e-25 89.9 0.0 4.8e-20 72.1 0.0 2.7 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KNE02610.1 - 6e-13 48.6 0.4 2.5e-12 46.6 0.5 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KNE02610.1 - 0.014 15.7 0.0 0.97 9.9 0.0 2.6 2 0 0 2 2 2 0 HAMP domain Mid2 PF04478.12 KNE02610.1 - 0.04 13.8 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DPPIV_N PF00930.21 KNE02611.1 - 1.1e-91 307.3 6.7 1.6e-91 306.7 6.7 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KNE02611.1 - 1.8e-43 148.5 0.1 2.9e-43 147.8 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KNE02611.1 - 0.0054 17.4 0.0 0.038 14.6 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.12 KNE02611.1 - 0.012 14.3 0.0 0.029 13.1 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 KNE02611.1 - 0.015 15.0 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KNE02611.1 - 0.018 14.3 0.0 0.055 12.7 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 KNE02611.1 - 0.094 12.3 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) TCTP PF00838.17 KNE02612.1 - 6.7e-73 244.5 3.3 7.5e-73 244.3 3.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein TRM13 PF05206.14 KNE02614.1 - 1.5e-72 244.3 3.4 2.3e-71 240.4 3.4 2.0 1 1 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.12 KNE02614.1 - 6.3e-10 38.7 0.7 1.4e-09 37.6 0.7 1.7 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.6 KNE02614.1 - 0.00019 21.5 1.4 0.00034 20.6 1.4 1.4 1 0 0 1 1 1 1 Methyltransferase domain BUD22 PF09073.10 KNE02615.1 - 1.8e-75 254.9 56.2 2.6e-75 254.4 56.2 1.3 1 1 0 1 1 1 1 BUD22 PRKCSH-like PF12999.7 KNE02616.1 - 1.6e-62 210.4 7.4 1.6e-62 210.4 7.4 2.7 2 1 1 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KNE02616.1 - 1.5e-44 151.4 0.1 3.5e-44 150.2 0.1 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PriC PF07445.12 KNE02616.1 - 0.022 14.7 0.1 0.022 14.7 0.1 2.2 2 1 0 2 2 2 0 Primosomal replication protein priC CC2-LZ PF16516.5 KNE02616.1 - 0.024 15.0 3.0 0.024 15.0 3.0 2.5 2 2 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Glycoprot_B_PH2 PF17417.2 KNE02616.1 - 0.34 11.3 2.0 0.4 11.1 0.6 1.8 2 0 0 2 2 2 0 Herpesvirus Glycoprotein B PH-like domain Fib_alpha PF08702.10 KNE02616.1 - 0.78 9.9 18.9 4.7 7.4 2.2 3.5 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 KNE02616.1 - 2.3 8.7 15.0 0.051 14.1 2.5 3.0 1 1 2 3 3 3 0 Protein of unknown function DUF16 PP_kinase_N PF13089.6 KNE02616.1 - 2.6 8.4 6.4 4 7.8 1.0 2.7 2 1 0 2 2 2 0 Polyphosphate kinase N-terminal domain DUF3552 PF12072.8 KNE02616.1 - 4.2 6.8 14.8 0.53 9.7 7.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) CLZ PF16526.5 KNE02616.1 - 5.5 7.4 11.7 3.4 8.1 1.5 3.8 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3450 PF11932.8 KNE02616.1 - 7.1 5.9 9.2 2.8 7.2 4.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) UTP15_C PF09384.10 KNE02617.1 - 0.084 12.6 0.1 0.42 10.3 0.0 2.1 2 0 0 2 2 2 0 UTP15 C terminal Interferon PF00143.19 KNE02617.1 - 0.092 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Interferon alpha/beta domain adh_short PF00106.25 KNE02618.1 - 1e-33 116.5 0.2 1.2e-33 116.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNE02618.1 - 3.4e-23 82.4 0.1 4.2e-23 82.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNE02618.1 - 0.055 13.4 0.1 0.086 12.8 0.1 1.5 1 1 0 1 1 1 0 KR domain THF_DHG_CYH_C PF02882.19 KNE02618.1 - 0.06 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain VBS PF08913.10 KNE02618.1 - 0.11 13.0 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 Vinculin Binding Site Robl_LC7 PF03259.17 KNE02618.1 - 0.13 12.1 0.2 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 Roadblock/LC7 domain YCII PF03795.14 KNE02619.1 - 4.7e-05 23.7 0.0 5.6e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain UCH PF00443.29 KNE02621.1 - 3.7e-48 164.3 0.9 1.2e-47 162.5 0.0 2.3 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KNE02621.1 - 1.6e-06 27.9 8.3 3.9e-06 26.7 2.1 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PSI_PsaF PF02507.15 KNE02621.1 - 0.058 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III DUF445 PF04286.12 KNE02622.1 - 0.12 12.1 2.0 0.56 10.0 1.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF445) YgaB PF14182.6 KNE02622.1 - 0.12 12.7 2.4 0.18 12.2 0.8 2.0 2 0 0 2 2 2 0 YgaB-like protein PH_18 PF18469.1 KNE02623.1 - 3.6e-41 140.4 2.0 5.7e-41 139.8 0.6 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain Rtt106 PF08512.12 KNE02623.1 - 9.9e-21 74.0 0.4 2.2e-20 72.9 0.4 1.6 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Rtt106_N PF18215.1 KNE02623.1 - 7.3e-06 25.6 0.0 1.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Histone chaperone Rtt106 N-terminal domain EF-hand_6 PF13405.6 KNE02624.1 - 0.0052 16.6 2.5 0.065 13.2 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KNE02624.1 - 0.0057 16.1 1.4 0.059 12.9 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KNE02624.1 - 0.36 10.4 2.0 0.53 9.9 0.1 2.0 2 0 0 2 2 2 0 EF hand Aminotran_1_2 PF00155.21 KNE02625.1 - 4.2e-26 92.0 0.0 5.5e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KNE02625.1 - 3.8e-05 22.7 0.0 6.1e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase PX PF00787.24 KNE02626.1 - 1.9e-13 50.4 0.6 6.6e-13 48.6 0.0 2.2 2 1 0 2 2 2 1 PX domain IF2_N PF04760.15 KNE02626.1 - 0.065 13.1 0.0 8.6 6.3 0.0 2.9 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region Snapin_Pallidin PF14712.6 KNE02626.1 - 0.24 11.8 12.8 0.1 13.0 5.3 2.3 2 0 0 2 2 2 0 Snapin/Pallidin LAMTOR PF15454.6 KNE02626.1 - 0.68 10.6 6.7 5.9 7.6 0.5 2.8 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Spc7 PF08317.11 KNE02626.1 - 2.4 7.0 19.7 3 6.6 9.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF948 PF06103.11 KNE02626.1 - 5.2 7.4 7.3 37 4.7 4.1 3.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2417 PF10329.9 KNE02627.1 - 1.7e-67 227.3 0.7 2.4e-67 226.8 0.7 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_1 PF00561.20 KNE02627.1 - 0.00048 19.9 0.0 0.00066 19.4 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KNE02627.1 - 0.00079 19.6 0.0 0.0013 18.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain ODV-E18 PF10717.9 KNE02629.1 - 0.21 11.5 0.7 0.27 11.1 0.7 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 FHA PF00498.26 KNE02630.1 - 6.9e-15 55.2 0.0 1.5e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KNE02630.1 - 4.7e-12 45.4 6.4 9.9e-12 44.4 6.4 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KNE02630.1 - 7.5e-07 29.4 10.8 7.5e-07 29.4 10.8 1.7 2 0 0 2 2 2 1 Ring finger domain Yop-YscD_cpl PF16697.5 KNE02630.1 - 3.9e-05 23.9 0.0 7.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 KNE02630.1 - 0.0014 18.5 10.9 0.0029 17.4 10.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KNE02630.1 - 0.0037 17.1 10.1 0.0037 17.1 10.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KNE02630.1 - 0.0076 16.2 8.2 0.0091 15.9 7.2 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KNE02630.1 - 0.065 13.3 4.8 0.15 12.1 4.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 KNE02630.1 - 0.067 13.1 6.3 0.17 11.8 6.3 1.7 1 0 0 1 1 1 0 PHD-finger DUF1610 PF07754.11 KNE02630.1 - 0.15 12.1 1.0 0.37 10.8 1.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) zf-RING_UBOX PF13445.6 KNE02630.1 - 1.2 9.2 10.3 2.8 8.1 10.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 KNE02630.1 - 3.1 8.2 13.1 1.3 9.4 9.8 2.1 2 1 0 2 2 1 0 RING-H2 zinc finger domain Sugar_tr PF00083.24 KNE02631.1 - 7.8e-92 308.5 27.5 9.7e-92 308.2 27.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNE02631.1 - 1.2e-19 70.5 32.2 2.9e-19 69.2 23.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KNE02631.1 - 1e-08 34.2 24.0 2.6e-06 26.3 1.2 2.9 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 KNE02631.1 - 0.0003 19.8 1.0 0.0003 19.8 1.0 2.7 2 1 0 3 3 3 1 MFS_1 like family MFS_4 PF06779.14 KNE02631.1 - 0.001 18.5 6.2 0.001 18.5 6.2 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB zf-met2 PF12907.7 KNE02631.1 - 0.078 13.1 0.1 0.23 11.6 0.1 1.9 1 0 0 1 1 1 0 Zinc-binding Fungal_trans PF04082.18 KNE02632.1 - 2.7e-05 23.3 1.6 3.9e-05 22.8 1.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KNE02635.1 - 6.9e-51 173.2 1.2 9.6e-51 172.8 1.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNE02635.1 - 2.3e-07 30.8 11.6 6.3e-07 29.4 11.6 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_1 PF00583.25 KNE02636.1 - 1.5e-16 60.6 0.0 1.9e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KNE02636.1 - 1.7e-08 34.8 0.0 2.9e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KNE02636.1 - 8.2e-07 29.0 0.0 1.1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KNE02636.1 - 2.5e-06 28.2 0.0 2.9e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KNE02636.1 - 9.2e-06 25.9 0.0 1.1e-05 25.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KNE02636.1 - 0.0033 17.5 0.1 0.0077 16.3 0.0 1.7 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF4307 PF14155.6 KNE02636.1 - 0.076 12.8 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) PanZ PF12568.8 KNE02636.1 - 0.086 12.6 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ His_Phos_1 PF00300.22 KNE02637.1 - 7.8e-31 107.3 0.0 1.1e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) E1-E2_ATPase PF00122.20 KNE02638.1 - 8.5e-34 116.6 23.8 1.2e-29 103.2 0.4 3.6 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KNE02638.1 - 5.4e-27 94.7 2.6 5.4e-27 94.7 2.6 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KNE02638.1 - 3.4e-19 70.0 0.0 1.6e-14 54.7 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KNE02638.1 - 3.9e-19 68.5 0.0 8.9e-19 67.4 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KNE02638.1 - 7e-15 54.5 0.0 1.6e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KNE02638.1 - 1.4e-06 28.3 0.5 0.00049 19.9 0.5 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase VKOR PF07884.14 KNE02638.1 - 0.066 13.4 14.2 0.13 12.4 1.2 3.0 3 0 0 3 3 3 0 Vitamin K epoxide reductase family NatB_MDM20 PF09797.9 KNE02641.1 - 2.7e-36 125.4 16.6 2e-31 109.3 2.7 3.3 2 1 1 3 3 3 2 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 KNE02641.1 - 6.6e-06 26.6 0.6 0.011 16.2 0.2 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KNE02641.1 - 0.00018 22.1 0.1 0.0088 16.7 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KNE02641.1 - 0.00027 21.4 0.7 1.4 9.7 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KNE02641.1 - 0.00093 19.1 1.2 3.1 8.1 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KNE02641.1 - 0.003 18.2 0.0 0.69 10.9 0.0 4.1 3 1 2 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KNE02641.1 - 0.021 15.1 8.4 0.43 10.8 2.1 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Dimerisation2 PF16864.5 KNE02641.1 - 0.13 12.3 0.7 0.7 9.9 0.0 2.5 3 0 0 3 3 3 0 Dimerisation domain TPR_8 PF13181.6 KNE02641.1 - 0.24 11.7 2.1 9.5 6.7 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Complex1_LYR PF05347.15 KNE02642.1 - 0.00038 20.5 0.5 0.00054 20.0 0.5 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF155 PF02582.14 KNE02643.1 - 0.023 14.8 0.7 0.1 12.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 LRR_4 PF12799.7 KNE02644.1 - 4e-07 30.2 4.1 0.0043 17.4 0.7 4.2 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KNE02644.1 - 7.4e-05 22.5 3.9 13 6.1 0.0 5.8 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 KNE02644.1 - 0.53 11.0 4.6 44 5.2 0.4 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat HMG_box PF00505.19 KNE02645.1 - 8.3e-17 61.4 2.3 8.3e-17 61.4 2.3 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KNE02645.1 - 8e-07 29.6 1.0 8e-07 29.6 1.0 2.8 3 0 0 3 3 3 1 HMG-box domain KTSC PF13619.6 KNE02653.1 - 0.022 14.6 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 KTSC domain CIAPIN1 PF05093.13 KNE02655.1 - 9.6e-42 141.6 5.9 2.7e-41 140.2 5.9 1.8 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KNE02655.1 - 3.8e-25 88.6 0.0 7e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Kinetochor_Ybp2 PF08568.10 KNE02655.1 - 0.021 13.3 0.1 0.057 11.9 0.1 1.6 2 0 0 2 2 2 0 Uncharacterised protein family, YAP/Alf4/glomulin Ndc80_HEC PF03801.13 KNE02657.1 - 1.1e-38 132.3 0.4 1.1e-38 132.3 0.4 2.4 3 0 0 3 3 3 1 HEC/Ndc80p family DUF5595 PF18077.1 KNE02657.1 - 0.0004 20.4 4.3 0.0004 20.4 4.3 4.7 4 2 3 7 7 7 1 Domain of unknown function (DUF5595) Gp-FAR-1 PF05823.12 KNE02657.1 - 0.017 15.5 5.1 0.017 15.5 5.1 3.0 2 2 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) CLZ PF16526.5 KNE02657.1 - 0.31 11.4 26.0 0.43 11.0 1.9 4.8 2 2 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc7 PF08317.11 KNE02657.1 - 0.78 8.6 37.8 0.9 8.4 20.0 2.8 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.6 KNE02657.1 - 1 8.7 22.1 0.4 10.0 2.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) DUF3502 PF12010.8 KNE02657.1 - 1.7 9.3 6.6 1.6 9.3 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3502) T2SSG PF08334.11 KNE02657.1 - 2.1 8.5 4.6 16 5.6 0.0 3.8 3 1 1 4 4 4 0 Type II secretion system (T2SS), protein G DUF1664 PF07889.12 KNE02657.1 - 2.1 8.4 21.7 0.34 11.0 1.9 3.9 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 KNE02657.1 - 6.2 6.9 45.9 0.061 13.4 18.2 4.2 2 2 1 4 4 4 0 TPR/MLP1/MLP2-like protein Histidinol_dh PF00815.20 KNE02657.1 - 6.4 5.7 7.6 0.26 10.3 0.9 1.8 2 0 0 2 2 2 0 Histidinol dehydrogenase MRP-L20 PF12824.7 KNE02658.1 - 1.7e-50 171.4 3.7 2e-50 171.2 3.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 KNE02658.1 - 2.8e-05 24.2 0.4 5.2e-05 23.4 0.4 1.5 1 1 0 1 1 1 1 Neugrin HTH_32 PF13565.6 KNE02658.1 - 0.003 18.1 1.5 0.031 14.9 0.0 2.4 1 1 1 2 2 2 1 Homeodomain-like domain Plasmodium_HRP PF05403.11 KNE02659.1 - 1e-05 25.5 11.9 1.1e-05 25.4 11.9 1.2 1 0 0 1 1 1 1 Plasmodium histidine-rich protein (HRPII/III) BUD22 PF09073.10 KNE02659.1 - 2 7.6 13.6 2.2 7.5 13.6 1.0 1 0 0 1 1 1 0 BUD22 DUF4769 PF15992.5 KNE02659.1 - 2.7 7.7 7.9 3.2 7.5 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) Nop53 PF07767.11 KNE02659.1 - 4.8 6.5 16.9 5.9 6.2 16.9 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Cwf_Cwc_15 PF04889.12 KNE02659.1 - 7.4 6.2 12.7 8.3 6.1 12.7 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Presenilin PF01080.17 KNE02659.1 - 8.4 5.0 7.7 9.2 4.9 7.7 1.2 1 0 0 1 1 1 0 Presenilin C2 PF00168.30 KNE02661.1 - 9.4e-11 41.9 0.0 2.1e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain PAP2_3 PF14378.6 KNE02663.1 - 3.7e-19 69.2 15.0 3.7e-19 69.2 15.0 2.3 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KNE02663.1 - 2.7e-14 53.1 8.8 2.7e-14 53.1 8.8 2.4 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KNE02663.1 - 0.051 14.1 7.3 0.24 12.0 7.3 2.1 1 0 0 1 1 1 0 PAP2 superfamily C-terminal RNA_pol_3_Rpc31 PF11705.8 KNE02667.1 - 2.3e-40 139.3 13.8 3e-40 138.9 13.8 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 KNE02667.1 - 0.097 12.0 6.3 0.12 11.7 6.3 1.1 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 KNE02667.1 - 3 5.9 12.1 2.8 5.9 12.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi WD40 PF00400.32 KNE02669.1 - 8.6e-18 64.4 0.7 1.7e-05 25.4 0.4 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNE02669.1 - 0.015 15.6 0.0 5.9 7.3 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nha1_C PF08619.10 KNE02669.1 - 0.039 13.2 11.3 0.072 12.3 11.3 1.3 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF4277 PF14104.6 KNE02669.1 - 0.14 12.5 0.1 0.27 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4277) PHTB1_N PF14727.6 KNE02669.1 - 0.18 11.1 0.0 2.7 7.2 0.0 2.2 2 0 0 2 2 2 0 PTHB1 N-terminus PGA2 PF07543.12 KNE02670.1 - 2.4e-09 37.3 14.3 7.5e-07 29.2 14.3 2.1 1 1 0 1 1 1 1 Protein trafficking PGA2 Phage_Gp23 PF10669.9 KNE02670.1 - 0.0014 18.9 2.6 0.0019 18.5 2.6 1.2 1 0 0 1 1 1 1 Protein gp23 (Bacteriophage A118) O-antigen_lig PF13425.6 KNE02670.1 - 0.0035 16.2 1.2 0.0042 15.9 1.2 1.0 1 0 0 1 1 1 1 O-antigen ligase like membrane protein SHR3_chaperone PF08229.11 KNE02670.1 - 0.014 14.4 0.2 0.024 13.6 0.2 1.4 1 0 0 1 1 1 0 ER membrane protein SH3 SecY PF00344.20 KNE02670.1 - 0.017 14.4 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 SecY translocase OmpH PF03938.14 KNE02670.1 - 0.029 14.7 6.6 0.038 14.3 6.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FAM176 PF14851.6 KNE02670.1 - 0.035 13.8 1.1 0.05 13.3 1.1 1.3 1 0 0 1 1 1 0 FAM176 family DivIC PF04977.15 KNE02670.1 - 0.23 11.3 6.3 0.37 10.6 0.3 2.3 2 0 0 2 2 2 0 Septum formation initiator MAP17 PF15807.5 KNE02670.1 - 0.24 11.7 3.4 0.32 11.2 3.4 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 NEMP PF10225.9 KNE02670.1 - 0.38 10.4 1.2 0.83 9.3 1.2 1.6 1 1 0 1 1 1 0 NEMP family Vpu PF00558.19 KNE02670.1 - 0.54 10.1 7.7 0.13 12.0 1.7 2.1 1 1 1 2 2 2 0 Vpu protein DUF4199 PF13858.6 KNE02670.1 - 2.9 8.3 4.3 43 4.5 4.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) Ubiquitin_2 PF14560.6 KNE02671.1 - 2.4e-19 69.6 0.1 4.3e-19 68.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 KNE02671.1 - 3.9e-19 68.4 0.2 5.8e-19 67.9 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain T4BSS_DotI_IcmL PF11393.8 KNE02671.1 - 0.094 12.2 0.3 0.63 9.5 0.1 2.0 2 0 0 2 2 2 0 Type-IV b secretion system, inner-membrane complex component LSM PF01423.22 KNE02672.1 - 1.9e-18 65.9 0.2 2.9e-18 65.3 0.2 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KNE02672.1 - 0.073 12.7 0.5 0.11 12.1 0.5 1.3 1 0 0 1 1 1 0 Hfq protein UPRTase PF14681.6 KNE02673.1 - 9.5e-76 253.8 0.0 1.2e-75 253.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Flu_C_NS1 PF03506.13 KNE02673.1 - 0.17 11.8 0.1 0.28 11.2 0.1 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Actin PF00022.19 KNE02674.1 - 8.5e-124 413.3 0.0 1.4e-122 409.3 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KNE02674.1 - 0.027 13.3 0.1 8.4 5.1 0.0 2.6 3 0 0 3 3 3 0 MreB/Mbl protein EF-hand_6 PF13405.6 KNE02675.1 - 0.0068 16.3 0.0 0.036 14.0 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain RNA_pol_Rpb6 PF01192.22 KNE02676.1 - 4.5e-15 55.3 0.1 6.5e-15 54.8 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 gp45-slide_C PF09116.10 KNE02676.1 - 0.09 12.8 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 gp45 sliding clamp, C terminal Peptidase_M16 PF00675.20 KNE02677.1 - 3e-20 72.7 0.0 4.9e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KNE02677.1 - 4.8e-06 26.7 0.0 1.4e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 Peptidase M16 inactive domain PIG-U PF06728.13 KNE02678.1 - 3.2e-101 339.2 31.9 3.7e-101 339.0 31.9 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U LSM PF01423.22 KNE02679.1 - 2.2e-14 52.9 0.3 2.9e-14 52.5 0.3 1.2 1 0 0 1 1 1 1 LSM domain NCBP3 PF10309.9 KNE02680.1 - 6.4e-24 83.6 3.1 1.5e-23 82.4 0.1 2.6 3 0 0 3 3 3 1 Nuclear cap-binding protein subunit 3 Ribosomal_L6e PF01159.19 KNE02680.1 - 3.5 8.2 8.4 1 9.9 1.4 2.8 3 0 0 3 3 3 0 Ribosomal protein L6e AAA PF00004.29 KNE02681.1 - 1.8e-41 141.7 0.0 2.9e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KNE02681.1 - 2.2e-28 98.0 0.1 7.8e-28 96.3 0.1 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KNE02681.1 - 2.6e-21 75.4 6.4 6.7e-21 74.1 6.4 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KNE02681.1 - 1.1e-07 31.5 0.0 1.4e-06 28.0 0.0 2.7 3 0 0 3 3 2 1 AAA+ lid domain RNA_helicase PF00910.22 KNE02681.1 - 9.8e-07 29.1 0.1 0.025 15.0 0.0 3.7 3 1 1 4 4 4 1 RNA helicase RuvB_N PF05496.12 KNE02681.1 - 1.9e-05 24.4 0.0 3.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KNE02681.1 - 2e-05 25.0 0.6 0.0011 19.4 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KNE02681.1 - 3.9e-05 24.0 0.1 0.017 15.4 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KNE02681.1 - 4e-05 23.6 0.0 0.0003 20.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KNE02681.1 - 8.2e-05 21.9 0.0 0.00034 19.9 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KNE02681.1 - 8.4e-05 22.4 0.0 0.00023 21.0 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KNE02681.1 - 0.00013 22.6 0.1 0.00069 20.2 0.0 2.4 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.6 KNE02681.1 - 0.00046 20.2 0.1 0.0018 18.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KNE02681.1 - 0.00059 19.2 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KNE02681.1 - 0.0018 18.4 0.1 0.0059 16.8 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_24 PF13479.6 KNE02681.1 - 0.0025 17.5 0.0 0.006 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KNE02681.1 - 0.0034 17.8 0.0 0.012 16.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.14 KNE02681.1 - 0.0044 17.2 0.0 0.013 15.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 KNE02681.1 - 0.017 14.7 0.3 0.11 11.9 0.0 2.3 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 KNE02681.1 - 0.024 14.2 0.1 0.42 10.2 0.1 2.3 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KNE02681.1 - 0.034 13.9 0.0 0.4 10.4 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 KNE02681.1 - 0.034 13.5 0.0 0.083 12.3 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KNE02681.1 - 0.039 13.3 0.0 4.4 6.6 0.0 2.4 1 1 1 2 2 2 0 KaiC Cytidylate_kin PF02224.18 KNE02681.1 - 0.053 13.2 0.1 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase Parvo_NS1 PF01057.17 KNE02681.1 - 0.067 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 KNE02681.1 - 0.07 12.6 0.1 0.17 11.3 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein Torsin PF06309.11 KNE02681.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Torsin NACHT PF05729.12 KNE02681.1 - 0.11 12.4 0.0 1 9.3 0.0 2.3 1 1 1 2 2 2 0 NACHT domain Ribosomal_S7 PF00177.21 KNE02683.1 - 5e-35 120.4 2.8 7.2e-35 119.8 2.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e OPT PF03169.15 KNE02684.1 - 2.9e-176 587.7 42.1 3.4e-176 587.5 42.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3099 PF11298.8 KNE02684.1 - 0.88 9.7 3.9 1.8 8.8 1.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) BofA PF07441.11 KNE02684.1 - 2.7 8.3 9.3 2.9 8.2 5.4 3.2 2 0 0 2 2 2 0 SigmaK-factor processing regulatory protein BofA DUF1700 PF08006.11 KNE02689.1 - 0.061 12.9 0.5 0.076 12.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) GST_C PF00043.25 KNE02691.1 - 2.7e-09 37.1 0.0 8.4e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KNE02691.1 - 5.2e-09 36.2 0.0 9.5e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KNE02691.1 - 2e-05 24.5 0.0 4.8e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KNE02691.1 - 0.13 12.9 0.0 0.24 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Putative_PNPOx PF01243.20 KNE02692.1 - 1.9e-13 50.4 0.1 2.2e-12 47.0 0.0 2.4 2 1 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 KNE02692.1 - 0.00046 20.2 0.0 0.012 15.6 0.0 2.2 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pectate_lyase22 PF14583.6 KNE02692.1 - 0.012 14.3 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 Oligogalacturonate lyase Pyrid_oxidase_2 PF13883.6 KNE02692.1 - 0.041 13.9 0.0 0.064 13.2 0.0 1.3 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DEP PF00610.21 KNE02693.1 - 0.18 11.9 0.0 0.2 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ORC4_C PF14629.6 KNE02694.1 - 3.6e-40 137.7 4.1 6.1e-40 136.9 4.1 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KNE02694.1 - 1.5e-13 51.5 0.0 3.8e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KNE02694.1 - 1.3e-12 48.2 0.1 3.8e-12 46.7 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KNE02694.1 - 7.9e-08 32.8 0.1 2.1e-07 31.4 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KNE02694.1 - 4.7e-06 26.7 0.9 7.4e-06 26.0 0.1 1.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KNE02694.1 - 0.00022 21.2 0.0 0.00099 19.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KNE02694.1 - 0.00039 20.0 0.0 0.00092 18.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region PTS_IIB PF02302.17 KNE02694.1 - 0.0011 19.6 0.0 0.8 10.4 0.0 3.6 3 0 0 3 3 3 1 PTS system, Lactose/Cellobiose specific IIB subunit DUF2075 PF09848.9 KNE02694.1 - 0.0021 17.3 0.1 0.0064 15.8 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 KNE02694.1 - 0.0041 17.2 0.2 0.11 12.6 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KNE02694.1 - 0.0048 17.3 0.0 0.053 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 KNE02694.1 - 0.0049 16.2 0.0 1.8 7.8 0.0 2.4 1 1 1 2 2 2 2 KAP family P-loop domain ABC_tran PF00005.27 KNE02694.1 - 0.047 14.2 0.1 1.1 9.8 0.0 2.6 2 0 0 2 2 2 0 ABC transporter DUF815 PF05673.13 KNE02694.1 - 0.052 12.7 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KNE02694.1 - 0.094 12.4 0.0 0.36 10.5 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Helicase_RecD PF05127.14 KNE02694.1 - 0.12 12.2 0.0 0.35 10.7 0.0 1.8 2 0 0 2 2 2 0 Helicase RGS PF00615.19 KNE02695.1 - 1.4e-13 51.1 0.0 1e-12 48.4 0.0 2.4 1 1 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 KNE02695.1 - 2.6e-13 49.8 0.1 7.1e-13 48.4 0.0 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) eIF2_C PF09173.11 KNE02696.1 - 3.1e-34 117.1 0.4 7.3e-34 115.9 0.4 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KNE02696.1 - 1.5e-23 83.3 0.0 1.3e-22 80.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KNE02696.1 - 5.3e-12 45.9 1.5 1.6e-11 44.4 0.5 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KNE02696.1 - 0.0034 17.4 0.0 0.0074 16.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNE02696.1 - 0.016 15.1 0.1 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase ProQ_C PF17516.2 KNE02696.1 - 0.083 12.3 0.2 0.21 11.1 0.2 1.7 1 0 0 1 1 1 0 ProQ C-terminal domain MMR_HSR1_Xtn PF16897.5 KNE02696.1 - 0.097 12.7 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Exo_endo_phos PF03372.23 KNE02697.1 - 2.1e-07 30.7 0.0 6.4e-07 29.1 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AAA PF00004.29 KNE02698.1 - 4.1e-10 40.2 0.0 1.1e-09 38.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KNE02698.1 - 1.5e-08 34.8 0.0 6.1e-08 32.8 0.0 2.1 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KNE02698.1 - 2.2e-07 31.2 0.0 6e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KNE02698.1 - 3.7e-07 30.7 1.7 7.7e-06 26.4 0.0 3.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 KNE02698.1 - 0.00044 20.3 0.0 0.0015 18.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KNE02698.1 - 0.0013 18.6 0.0 0.0086 16.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 KNE02698.1 - 0.003 17.3 3.5 0.0036 17.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KNE02698.1 - 0.012 16.1 0.7 0.07 13.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KNE02698.1 - 0.016 15.4 0.5 0.041 14.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KNE02698.1 - 0.02 14.9 0.0 0.065 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KNE02698.1 - 0.029 14.8 0.0 0.61 10.5 0.0 2.9 3 0 0 3 3 3 0 RNA helicase AAA_7 PF12775.7 KNE02698.1 - 0.034 13.6 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_assoc_2 PF16193.5 KNE02698.1 - 0.092 13.1 1.0 4.7 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA C-terminal domain AAA_11 PF13086.6 KNE02698.1 - 1.9 8.2 0.0 1.9 8.2 0.0 3.5 3 1 0 3 3 2 0 AAA domain DUF1712 PF08217.11 KNE02699.1 - 3.6e-17 62.1 4.3 2.2e-12 46.3 0.1 3.5 3 1 0 3 3 3 3 Fungal domain of unknown function (DUF1712) DUF3074 PF11274.8 KNE02700.1 - 9.7e-27 94.1 0.0 1.3e-26 93.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) START PF01852.19 KNE02700.1 - 0.029 13.8 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 START domain zf-MYND PF01753.18 KNE02701.1 - 1.2e-06 28.4 20.2 2.9e-06 27.3 20.2 1.6 1 0 0 1 1 1 1 MYND finger SelP_N PF04592.14 KNE02701.1 - 2.7 7.3 16.1 5.6 6.3 16.1 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Peptidase_C50 PF03568.17 KNE02702.1 - 2.1e-95 320.2 0.0 5.1e-95 318.9 0.0 1.7 1 0 0 1 1 1 1 Peptidase family C50 NLRC4_HD PF17889.1 KNE02702.1 - 4.3 7.7 7.2 4.1 7.8 0.2 3.8 3 0 0 3 3 3 0 NLRC4 helical domain Flavin_Reduct PF01613.18 KNE02703.1 - 1.5e-24 86.8 0.0 1.8e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain COG5 PF10392.9 KNE02704.1 - 0.21 11.8 15.9 0.068 13.3 4.3 3.1 2 1 1 3 3 3 0 Golgi transport complex subunit 5 EF1_GNE PF00736.19 KNE02704.1 - 0.61 10.3 2.5 27 5.0 0.1 2.5 2 0 0 2 2 2 0 EF-1 guanine nucleotide exchange domain DUF3450 PF11932.8 KNE02704.1 - 0.77 9.0 21.1 0.14 11.5 2.4 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) AAA_13 PF13166.6 KNE02704.1 - 0.91 8.1 15.7 2.8 6.5 15.7 1.6 1 1 0 1 1 1 0 AAA domain Tup_N PF08581.10 KNE02704.1 - 0.99 9.8 17.2 0.43 10.9 1.3 3.4 3 0 0 3 3 3 0 Tup N-terminal Filament PF00038.21 KNE02704.1 - 1.3 8.5 24.6 1.6 8.2 0.8 2.8 2 1 0 2 2 2 0 Intermediate filament protein ADIP PF11559.8 KNE02704.1 - 1.5 8.9 26.6 0.61 10.2 8.2 3.2 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 KNE02704.1 - 1.7 9.2 23.2 0.34 11.5 9.3 2.9 1 1 1 2 2 2 0 Apg6 coiled-coil region FAM76 PF16046.5 KNE02704.1 - 2.1 7.6 16.5 4.5 6.5 16.5 1.6 1 0 0 1 1 1 0 FAM76 protein FlaC_arch PF05377.11 KNE02704.1 - 3.2 8.2 15.6 9.4 6.7 0.3 4.4 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Med9 PF07544.13 KNE02704.1 - 3.4 7.8 15.0 0.28 11.3 7.0 2.8 2 2 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DivIC PF04977.15 KNE02704.1 - 3.5 7.5 23.5 1.9 8.3 3.4 4.3 2 1 3 5 5 5 0 Septum formation initiator DUF641 PF04859.12 KNE02704.1 - 4.1 7.7 16.9 5.9 7.2 5.3 2.9 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF4618 PF15397.6 KNE02704.1 - 4.2 6.7 23.8 9.5 5.5 23.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Csm1_N PF18504.1 KNE02704.1 - 4.2 7.8 20.5 9 6.7 3.2 4.0 3 1 1 4 4 4 0 Csm1 N-terminal domain Phage_GPO PF05929.11 KNE02704.1 - 4.5 6.8 11.9 0.24 11.0 3.9 2.2 1 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase NPV_P10 PF05531.12 KNE02704.1 - 6 7.4 8.9 2.6 8.5 2.1 3.3 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein PIN_8 PF18476.1 KNE02704.1 - 6.7 6.5 14.1 0.67 9.8 3.5 2.3 1 1 1 2 2 2 0 PIN like domain YabA PF06156.13 KNE02704.1 - 7.5 7.3 19.0 4 8.1 4.9 3.7 1 1 2 3 3 3 0 Initiation control protein YabA Fez1 PF06818.15 KNE02704.1 - 7.7 6.9 24.3 14 6.0 15.2 2.3 1 1 1 2 2 2 0 Fez1 LPP PF04728.13 KNE02704.1 - 8.3 6.9 11.0 20 5.6 0.1 4.0 4 1 1 5 5 4 0 Lipoprotein leucine-zipper Atg14 PF10186.9 KNE02704.1 - 8.4 5.4 27.4 6.8e+02 -0.9 27.4 2.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2401 PF10287.9 KNE02706.1 - 5.1e-81 271.6 1.4 5.1e-81 271.6 1.4 1.6 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 KNE02706.1 - 6.3e-22 77.8 0.1 1.6e-21 76.5 0.1 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) FtsJ PF01728.19 KNE02708.1 - 6.8e-55 185.9 0.0 7.8e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 KNE02708.1 - 0.011 15.6 0.0 0.051 13.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain DUF2403 PF10290.9 KNE02708.1 - 0.036 14.5 0.1 0.35 11.3 0.0 2.1 2 0 0 2 2 2 0 Glycine-rich protein domain (DUF2403) Mpp10 PF04006.12 KNE02709.1 - 5.7e-129 431.3 58.4 7.6e-129 430.9 58.4 1.1 1 0 0 1 1 1 1 Mpp10 protein DeoC PF01791.9 KNE02709.1 - 0.029 14.0 0.2 0.055 13.1 0.2 1.4 1 0 0 1 1 1 0 DeoC/LacD family aldolase YabA PF06156.13 KNE02709.1 - 0.81 10.4 0.0 0.81 10.4 0.0 4.7 5 1 0 5 5 5 0 Initiation control protein YabA Say1_Mug180 PF10340.9 KNE02714.1 - 9.5e-17 60.9 0.0 5.3e-16 58.4 0.0 1.9 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 KNE02714.1 - 2e-11 44.2 0.0 2.9e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.16 KNE02716.1 - 3.3e-14 52.6 44.5 1.5e-11 43.8 42.7 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KNE02716.1 - 0.00013 20.5 23.1 0.00019 20.0 23.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Tmemb_18A PF09771.9 KNE02716.1 - 0.035 14.5 0.2 0.035 14.5 0.2 2.4 3 0 0 3 3 3 0 Transmembrane protein 188 Say1_Mug180 PF10340.9 KNE02718.1 - 2.9e-18 65.9 0.0 1.1e-17 64.0 0.0 1.7 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 KNE02718.1 - 3.1e-09 37.0 0.0 6.7e-09 35.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold ETRAMP PF09716.10 KNE02720.1 - 0.9 9.6 4.7 0.44 10.6 2.1 1.8 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) PIR PF00399.19 KNE02721.1 - 9.4e-20 69.6 117.5 0.0001 21.7 4.4 11.1 10 1 0 10 10 10 10 Yeast PIR protein repeat TFIIA PF03153.13 KNE02721.1 - 0.038 14.0 25.5 0.051 13.6 25.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Asp PF00026.23 KNE02722.1 - 1.1e-44 153.2 0.9 3.7e-37 128.4 0.3 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KNE02722.1 - 3.2e-06 27.5 0.1 3e-05 24.3 0.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal HPP PF04982.13 KNE02723.1 - 9.1e-36 122.7 6.5 9.1e-36 122.7 6.5 1.7 2 0 0 2 2 2 1 HPP family TMEM190 PF15431.6 KNE02723.1 - 0.062 13.5 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 190 DUF2427 PF10348.9 KNE02723.1 - 0.45 10.3 5.1 1.8 8.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) Frag1 PF10277.9 KNE02724.1 - 4e-54 183.5 26.8 4.8e-54 183.2 26.8 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family T6SS_VasE PF05936.12 KNE02724.1 - 0.094 11.4 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE RNB PF00773.19 KNE02725.1 - 2.2e-99 332.9 0.0 3.4e-99 332.3 0.0 1.3 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 KNE02725.1 - 1.2e-45 154.8 0.0 3.6e-45 153.3 0.0 1.8 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 KNE02725.1 - 3e-30 104.0 2.1 1.1e-29 102.2 2.1 2.0 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 KNE02725.1 - 1.2e-19 70.1 0.0 2.7e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 KNE02725.1 - 7.2e-15 55.4 1.1 1.8e-14 54.1 1.1 1.7 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 KNE02725.1 - 4.5e-09 36.3 0.0 1.1e-05 25.5 0.0 3.0 2 0 0 2 2 2 2 Cold shock domain OB_RNB PF08206.11 KNE02725.1 - 0.015 15.0 0.2 0.098 12.3 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF4862 PF16154.5 KNE02725.1 - 0.076 12.4 0.0 0.65 9.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4862) Lipase_GDSL_3 PF14606.6 KNE02725.1 - 0.13 12.3 1.3 2.5 8.2 0.0 2.7 3 0 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase family DHBP_synthase PF00926.19 KNE02726.1 - 4e-87 290.7 0.1 4.5e-87 290.6 0.1 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase POC3_POC4 PF10448.9 KNE02727.1 - 3.2e-22 79.1 0.0 3.6e-22 78.9 0.0 1.0 1 0 0 1 1 1 1 20S proteasome chaperone assembly proteins 3 and 4 tRNA-synt_1b PF00579.25 KNE02728.1 - 4.2e-18 65.7 0.0 3.5e-12 46.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Ribosomal_L27e PF01777.18 KNE02730.1 - 1.5e-19 70.1 1.1 1.6e-19 70.0 1.1 1.0 1 0 0 1 1 1 1 Ribosomal L27e protein family SMN PF06003.12 KNE02730.1 - 0.06 12.6 0.3 0.067 12.4 0.3 1.0 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Pkinase PF00069.25 KNE02731.1 - 3.6e-64 216.7 0.0 5.3e-64 216.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNE02731.1 - 1.9e-30 106.0 0.0 3.1e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNE02731.1 - 8.2e-05 22.0 0.0 0.00032 20.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KNE02731.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KNE02731.1 - 0.037 12.8 0.0 0.17 10.6 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 KNE02731.1 - 0.064 12.9 0.3 1.5 8.4 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KNE02731.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.16 KNE02732.1 - 1.2e-09 37.5 40.4 1.3e-05 24.3 22.2 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KNE02732.1 - 1.1e-08 34.0 22.1 1.1e-07 30.7 10.2 2.3 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) CRIM PF16978.5 KNE02733.1 - 2e-25 89.6 0.5 2.7e-24 85.9 0.0 3.0 3 0 0 3 3 3 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KNE02733.1 - 1.1e-15 57.8 3.1 9.8e-15 54.8 3.1 2.5 1 1 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology RA PF00788.23 KNE02733.1 - 0.11 13.2 0.0 37 5.1 0.0 3.0 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain RNase_T PF00929.24 KNE02735.1 - 5.1e-12 46.7 0.0 7.4e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RasGAP PF00616.19 KNE02736.1 - 3.2e-24 85.8 3.8 1.1e-15 57.9 0.3 3.5 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase ATP19 PF11022.8 KNE02739.1 - 1.8e-25 89.1 0.0 2.1e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit K Brix PF04427.18 KNE02740.1 - 5.3e-42 144.1 0.5 6.7e-42 143.8 0.5 1.1 1 0 0 1 1 1 1 Brix domain E2F_TDP PF02319.20 KNE02741.1 - 0.0053 16.8 0.0 0.0053 16.8 0.0 1.1 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Rhomboid PF01694.22 KNE02742.1 - 9.3e-30 103.6 11.4 9.3e-30 103.6 11.4 1.9 2 0 0 2 2 2 1 Rhomboid family E1-E2_ATPase PF00122.20 KNE02742.1 - 0.2 11.1 0.3 0.83 9.1 0.0 2.1 2 0 0 2 2 2 0 E1-E2 ATPase LRRC37AB_C PF14914.6 KNE02742.1 - 0.23 11.4 0.0 0.56 10.1 0.0 1.6 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF4125 PF13526.6 KNE02743.1 - 0.046 13.3 0.0 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4125) DUF2721 PF11026.8 KNE02745.1 - 0.098 12.6 1.0 0.15 11.9 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF29 PF01724.16 KNE02747.1 - 0.037 14.2 0.1 0.038 14.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF29 Ribosomal_L50 PF10501.9 KNE02749.1 - 4.8e-26 91.0 0.0 1.1e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S CBS PF00571.28 KNE02750.1 - 4.9e-34 116.6 7.3 2.4e-09 37.5 0.0 6.3 6 1 0 6 6 6 5 CBS domain PB1 PF00564.24 KNE02750.1 - 5.3e-11 42.3 0.3 1.1e-10 41.3 0.3 1.5 1 0 0 1 1 1 1 PB1 domain DUF5645 PF18713.1 KNE02751.1 - 0.08 13.2 0.6 9.7 6.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5645) Prenyltransf PF01255.19 KNE02752.1 - 1.3e-06 28.2 0.0 1.6e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Prenyltransf PF01255.19 KNE02753.1 - 1.2e-39 136.2 0.0 1.4e-39 136.0 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Vma12 PF11712.8 KNE02754.1 - 1.7e-38 131.8 0.1 2.6e-38 131.2 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DnaG_DnaB_bind PF08278.11 KNE02754.1 - 6.7e-06 26.7 1.6 0.00032 21.3 0.0 2.3 1 1 1 2 2 2 1 DNA primase DnaG DnaB-binding DUF4736 PF15883.5 KNE02754.1 - 0.016 14.9 0.3 0.032 14.0 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) Cyt_c_ox_IV PF12270.8 KNE02754.1 - 0.021 15.0 0.5 0.034 14.3 0.5 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Ycf70 PF17382.2 KNE02754.1 - 0.051 14.0 1.6 2.3 8.7 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized Ycf70-like tRNA_SAD PF07973.14 KNE02755.1 - 3.1e-12 46.4 0.2 7.3e-12 45.2 0.2 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 KNE02755.1 - 7e-10 38.0 0.1 3e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (A) Ribosomal_S9 PF00380.19 KNE02756.1 - 1.1e-42 145.3 0.2 2.1e-42 144.4 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Myb_DNA-binding PF00249.31 KNE02757.1 - 3.1e-13 49.7 0.0 2.8e-07 30.6 0.0 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KNE02757.1 - 7.7e-06 26.1 3.6 0.0059 16.8 0.1 3.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KNE02757.1 - 0.00025 20.9 2.2 0.00063 19.6 0.1 2.7 2 0 0 2 2 2 1 Myb DNA-binding like GyrB_insert PF18053.1 KNE02757.1 - 0.051 13.5 2.0 0.12 12.2 0.7 2.2 2 0 0 2 2 2 0 DNA gyrase B subunit insert domain AAA_22 PF13401.6 KNE02759.1 - 2.1e-10 41.0 0.0 4.5e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KNE02759.1 - 2.2e-09 37.9 0.3 2.3e-07 31.3 0.2 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KNE02759.1 - 2e-08 34.7 0.0 9.2e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KNE02759.1 - 0.00017 21.6 0.3 0.00037 20.6 0.3 1.5 1 0 0 1 1 1 1 AAA lid domain T2SSE PF00437.20 KNE02759.1 - 0.0014 17.8 0.1 0.0076 15.3 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein ATPase_2 PF01637.18 KNE02759.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 KNE02759.1 - 0.072 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_19 PF13245.6 KNE02759.1 - 0.086 13.2 0.0 0.26 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain SieB PF14163.6 KNE02759.1 - 0.11 12.0 0.1 0.53 9.8 0.1 2.1 1 1 0 1 1 1 0 Super-infection exclusion protein B RNA_helicase PF00910.22 KNE02759.1 - 0.15 12.5 0.2 0.74 10.2 0.1 2.3 2 1 0 2 2 2 0 RNA helicase dbPDZ_assoc PF16610.5 KNE02759.1 - 0.15 12.3 0.2 2.7 8.3 0.1 2.5 2 0 0 2 2 2 0 Unstructured region between two PDZ domains on Dlg5 CENP-S PF15630.6 KNE02760.1 - 7.9e-29 99.9 0.0 1e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KNE02760.1 - 4.1e-08 33.3 0.1 4.8e-08 33.1 0.1 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Amelotin PF15757.5 KNE02760.1 - 0.00042 19.9 0.0 0.00046 19.8 0.0 1.1 1 0 0 1 1 1 1 Amelotin TFIID-18kDa PF02269.16 KNE02760.1 - 0.058 13.4 0.0 0.087 12.9 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit CBS PF00571.28 KNE02760.1 - 0.096 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 CBS domain DUF3337 PF11816.8 KNE02761.1 - 7.1e-45 153.0 0.4 2.1e-44 151.5 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KNE02761.1 - 1.3e-10 41.7 16.0 2.5e-05 24.9 0.1 6.8 9 0 0 9 9 9 3 WD domain, G-beta repeat RAWUL PF16207.5 KNE02761.1 - 0.019 15.6 0.1 0.062 14.0 0.1 1.9 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like ANAPC4_WD40 PF12894.7 KNE02761.1 - 0.043 14.1 0.0 23 5.4 0.0 3.7 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_Rpb5_C PF01191.19 KNE02762.1 - 2.1e-32 110.8 0.4 3.9e-32 109.9 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KNE02762.1 - 1.5e-26 92.8 0.0 2.4e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain SH3_2 PF07653.17 KNE02762.1 - 0.063 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain DUF3648 PF12364.8 KNE02762.1 - 0.1 12.8 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3648) RibD_C PF01872.17 KNE02763.1 - 2.7e-32 112.2 0.0 3.3e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain Pollen_allerg_2 PF01620.16 KNE02763.1 - 0.02 15.1 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) ELO PF01151.18 KNE02765.1 - 7.7e-60 202.5 23.8 9.4e-60 202.2 23.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family PfkB PF00294.24 KNE02767.1 - 6.7e-50 170.1 4.5 1.1e-49 169.4 4.5 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Peptidase_S15 PF02129.18 KNE02767.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF5123 PF17161.4 KNE02767.1 - 0.12 13.4 0.4 0.56 11.3 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5123) PCI PF01399.27 KNE02768.1 - 1.7e-10 41.3 0.3 9.2e-10 39.0 0.3 2.4 1 0 0 1 1 1 1 PCI domain BCIP PF13862.6 KNE02770.1 - 3.5e-66 222.9 1.7 4.8e-66 222.5 1.7 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein UCH PF00443.29 KNE02771.1 - 8.1e-14 51.7 0.0 1.9e-13 50.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KNE02771.1 - 9e-08 32.1 0.0 0.005 16.5 0.0 2.9 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase BAR PF03114.18 KNE02773.1 - 1.2e-36 126.6 9.0 2e-36 125.9 9.0 1.4 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.13 KNE02773.1 - 7.7e-08 32.2 6.2 1.4e-07 31.4 6.2 1.4 1 1 0 1 1 1 1 Arfaptin-like domain BBE PF08031.12 KNE02773.1 - 0.017 15.2 0.1 0.042 13.9 0.1 1.8 1 0 0 1 1 1 0 Berberine and berberine like T3SSipB PF16535.5 KNE02773.1 - 0.32 11.5 8.6 3.7 8.0 2.1 2.9 2 1 0 2 2 2 0 Type III cell invasion protein SipB Mt_ATP-synt_B PF05405.14 KNE02773.1 - 0.46 10.1 7.7 0.76 9.4 0.1 2.9 3 0 0 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF4164 PF13747.6 KNE02773.1 - 6.4 7.1 12.1 6.2 7.2 0.2 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4164) AMPKBI PF04739.15 KNE02774.1 - 1.4e-27 95.8 2.1 1.4e-27 95.8 2.1 2.3 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 KNE02774.1 - 1.1e-16 60.8 0.0 4.4e-16 58.9 0.0 2.0 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase zf-HC5HC2H_2 PF13832.6 KNE02778.1 - 6.8e-31 106.7 18.9 3.5e-30 104.4 7.2 3.4 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KNE02778.1 - 9e-26 90.0 5.8 9e-26 90.0 5.8 4.3 4 0 0 4 4 4 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KNE02778.1 - 3.7e-14 52.0 1.7 3.7e-14 52.0 1.7 2.4 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KNE02778.1 - 1.9e-10 40.4 5.6 1.9e-10 40.4 5.6 3.0 3 0 0 3 3 3 1 PHD-finger EPL1 PF10513.9 KNE02778.1 - 3.2e-07 30.8 0.0 6.2e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 Enhancer of polycomb-like Prok-RING_1 PF14446.6 KNE02778.1 - 0.0064 16.4 2.3 0.0064 16.4 2.3 2.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 C1_1 PF00130.22 KNE02778.1 - 0.011 15.6 3.2 0.011 15.6 3.2 3.1 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 KNE02778.1 - 0.014 15.0 3.0 0.014 15.0 3.0 2.6 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain FYVE_2 PF02318.16 KNE02778.1 - 2.4 8.4 11.8 0.051 13.8 1.4 2.7 2 0 0 2 2 2 0 FYVE-type zinc finger TEA PF01285.18 KNE02782.1 - 6.1e-24 83.9 0.0 1.2e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 TEA/ATTS domain AIRC PF00731.20 KNE02783.1 - 4.6e-63 211.2 2.0 2.9e-62 208.6 1.1 2.2 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 KNE02783.1 - 2.2e-60 203.1 0.0 3.6e-60 202.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KNE02783.1 - 5.4e-19 67.6 0.0 1.1e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 KNE02783.1 - 2.3e-07 30.5 0.0 3.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain 2-Hacid_dh_C PF02826.19 KNE02783.1 - 0.0003 20.2 0.1 0.00071 19.0 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KNE02783.1 - 0.0059 15.9 0.3 0.013 14.9 0.3 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Dala_Dala_lig_C PF07478.13 KNE02783.1 - 0.012 15.2 0.0 0.097 12.2 0.0 2.2 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus NPV_P10 PF05531.12 KNE02783.1 - 0.08 13.4 0.2 0.25 11.8 0.2 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF2423 PF10338.9 KNE02784.1 - 2.8e-14 53.0 11.0 2.8e-14 53.0 11.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) DUF2721 PF11026.8 KNE02784.1 - 0.097 12.6 0.2 0.11 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) RPN2_C PF18004.1 KNE02784.1 - 1.8 8.4 10.8 2.2 8.2 10.8 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain bZIP_Maf PF03131.17 KNE02785.1 - 0.006 17.1 2.1 0.006 17.1 2.1 1.0 1 0 0 1 1 1 1 bZIP Maf transcription factor Ribosomal_L19e PF01280.20 KNE02786.1 - 9.2e-31 106.8 4.7 9.2e-31 106.8 4.7 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e Flot PF15975.5 KNE02786.1 - 0.52 10.5 8.1 0.83 9.9 8.1 1.3 1 0 0 1 1 1 0 Flotillin RGS PF00615.19 KNE02787.1 - 9.1e-06 25.9 0.2 0.00013 22.2 0.0 2.4 2 0 0 2 2 2 1 Regulator of G protein signaling domain zf-C2H2 PF00096.26 KNE02793.1 - 4.4e-05 23.7 1.2 4.4e-05 23.7 1.2 3.7 3 1 1 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KNE02793.1 - 0.0052 17.5 18.1 0.0067 17.2 1.2 4.5 4 1 1 5 5 5 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KNE02793.1 - 0.017 15.6 6.5 0.62 10.6 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double domain LIM PF00412.22 KNE02793.1 - 0.065 13.5 3.2 5.8 7.2 0.1 2.4 2 0 0 2 2 2 0 LIM domain zf_C2H2_ZHX PF18387.1 KNE02793.1 - 0.18 11.5 3.6 0.99 9.1 0.9 2.6 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain RNA_POL_M_15KD PF02150.16 KNE02793.1 - 0.18 11.7 1.7 8.1 6.4 0.1 2.5 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-C2H2_6 PF13912.6 KNE02793.1 - 3.4 7.8 9.2 0.27 11.3 1.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2205 PF10224.9 KNE02796.1 - 0.00028 20.8 1.8 0.00033 20.6 1.8 1.2 1 0 0 1 1 1 1 Short coiled-coil protein HAP1_N PF04849.13 KNE02796.1 - 0.00029 20.1 1.5 0.00029 20.1 1.5 1.0 1 0 0 1 1 1 1 HAP1 N-terminal conserved region MYO10_CC PF16735.5 KNE02796.1 - 0.0021 18.1 0.7 0.0027 17.8 0.7 1.2 1 0 0 1 1 1 1 Unconventional myosin-X coiled coil domain Dynactin_p22 PF07426.11 KNE02796.1 - 0.0035 17.2 0.8 0.0035 17.2 0.8 1.0 1 0 0 1 1 1 1 Dynactin subunit p22 RBD-FIP PF09457.10 KNE02796.1 - 0.42 10.6 3.7 18 5.4 3.7 2.1 1 1 0 1 1 1 0 FIP domain FoP_duplication PF13865.6 KNE02798.1 - 9.7e-05 22.8 2.8 0.00017 22.1 2.8 1.5 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.22 KNE02798.1 - 0.0012 18.6 0.1 0.0027 17.5 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phlebovirus_NSM PF07246.11 KNE02798.1 - 0.0096 15.3 2.9 0.0092 15.4 2.9 1.2 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M EMC3_TMCO1 PF01956.16 KNE02798.1 - 1.5 8.5 8.4 2.1 8.1 8.4 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like SPA PF08616.10 KNE02799.1 - 2.1e-32 111.5 0.0 5e-32 110.2 0.0 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 KNE02799.1 - 3.9e-21 75.9 0.2 1e-20 74.6 0.2 1.7 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 KNE02799.1 - 2.8e-14 52.6 0.2 4.2e-10 38.9 0.0 2.4 2 0 0 2 2 2 2 Transport protein Avl9 DENN PF02141.21 KNE02799.1 - 0.00031 20.7 1.0 0.38 10.7 0.0 2.7 3 0 0 3 3 3 2 DENN (AEX-3) domain DUF2347 PF09804.9 KNE02799.1 - 0.0021 17.7 0.2 0.027 14.1 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Acyltransferase PF01553.21 KNE02802.1 - 2.2e-31 108.2 0.0 3.9e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase SDF PF00375.18 KNE02803.1 - 0.13 11.3 1.6 0.14 11.2 1.6 1.0 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family GIT_SHD PF08518.11 KNE02804.1 - 2.9e-21 74.8 7.5 1.2e-10 40.8 2.1 2.9 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 KNE02804.1 - 2e-07 31.1 1.4 2e-07 31.1 1.4 3.4 2 1 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term AHD PF17793.1 KNE02804.1 - 0.33 10.8 1.7 9 6.2 0.5 2.9 2 0 0 2 2 2 0 ANC1 homology domain (AHD) Shadoo PF14999.6 KNE02804.1 - 1.5 8.9 7.0 6.6 6.8 0.3 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective TSC22 PF01166.18 KNE02804.1 - 2.8 8.3 8.6 26 5.2 0.1 4.0 3 0 0 3 3 3 0 TSC-22/dip/bun family GIT_CC PF16559.5 KNE02804.1 - 3.4 7.6 14.1 0.19 11.6 4.1 3.5 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cwf_Cwc_15 PF04889.12 KNE02805.1 - 3.2e-13 50.0 17.7 5.7e-07 29.5 12.6 2.4 1 1 1 2 2 2 2 Cwf15/Cwc15 cell cycle control protein TPR_19 PF14559.6 KNE02806.1 - 5.2e-06 26.9 12.1 0.0092 16.5 0.3 4.6 4 1 1 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KNE02806.1 - 5.3e-06 26.6 2.8 0.00079 19.6 0.1 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KNE02806.1 - 1.3e-05 24.9 3.7 0.14 12.3 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KNE02806.1 - 0.00019 21.4 0.4 0.28 11.5 0.0 3.4 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KNE02806.1 - 0.00035 20.2 6.2 0.23 11.2 0.0 4.1 3 1 1 4 4 4 2 TPR repeat TPR_1 PF00515.28 KNE02806.1 - 0.0004 20.1 0.5 1.8 8.5 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KNE02806.1 - 0.0043 17.8 8.7 3.6 8.7 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 KNE02806.1 - 0.0071 15.6 0.3 0.11 11.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat ChAPs PF09295.10 KNE02806.1 - 0.011 14.7 0.2 0.026 13.5 0.0 1.6 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_12 PF13424.6 KNE02806.1 - 0.02 15.2 3.4 1.5 9.2 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KNE02806.1 - 0.023 15.3 2.8 15 6.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KNE02806.1 - 0.083 13.6 8.8 0.1 13.3 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KNE02806.1 - 0.1 13.0 0.2 8 7.1 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Nexin_C PF08628.12 KNE02807.1 - 0.086 13.4 0.6 0.71 10.5 0.0 2.3 2 0 0 2 2 2 0 Sorting nexin C terminal DUF4477 PF14780.6 KNE02807.1 - 0.13 11.8 4.3 1.7 8.2 0.3 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4477) zf-H2C2_2 PF13465.6 KNE02808.1 - 8.7e-05 22.8 8.8 0.0012 19.2 0.8 4.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KNE02808.1 - 0.0011 19.3 7.0 0.0011 19.3 7.0 3.4 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KNE02808.1 - 0.0022 18.7 4.4 0.0022 18.7 4.4 4.5 4 0 0 4 4 4 1 C2H2-type zinc finger zf-Di19 PF05605.12 KNE02808.1 - 1.6 9.1 8.6 1.6 9.1 5.2 2.6 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Spermine_synth PF01564.17 KNE02811.1 - 2.2e-52 177.2 0.2 3e-52 176.8 0.2 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_31 PF13847.6 KNE02811.1 - 0.00024 20.9 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNE02811.1 - 0.032 14.9 0.0 0.089 13.5 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain DUF43 PF01861.16 KNE02811.1 - 0.033 13.4 0.3 0.055 12.7 0.3 1.4 1 1 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain NAD_binding_7 PF13241.6 KNE02811.1 - 0.15 12.6 0.2 0.43 11.1 0.2 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding AFT PF08731.11 KNE02813.1 - 1.5e-07 31.8 0.1 1.5e-07 31.8 0.1 2.1 3 0 0 3 3 3 1 Transcription factor AFT FAR1 PF03101.15 KNE02813.1 - 0.079 13.7 3.3 0.6 10.8 3.3 2.3 1 1 0 1 1 1 0 FAR1 DNA-binding domain Tho2 PF11262.8 KNE02813.1 - 0.51 9.5 4.6 1.2 8.3 4.6 1.5 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 CRAL_TRIO_2 PF13716.6 KNE02815.1 - 5.3e-13 49.3 1.6 5.9e-13 49.2 0.3 1.8 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 KNE02815.1 - 0.00053 19.8 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain Cdh1_DBD_1 PF18196.1 KNE02815.1 - 0.073 13.4 0.1 0.33 11.3 0.1 2.1 1 1 1 2 2 2 0 Chromodomain helicase DNA-binding domain 1 DASH_Dad1 PF08649.10 KNE02818.1 - 2.6e-23 82.0 0.1 3.2e-23 81.7 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 AMP-binding PF00501.28 KNE02819.1 - 0.00051 18.7 0.0 0.36 9.4 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Imm8 PF15586.6 KNE02819.1 - 0.04 14.0 0.0 0.084 12.9 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 8 Metallophos PF00149.28 KNE02820.1 - 3.9e-11 43.8 0.0 6.3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Hom_end PF05204.14 KNE02820.1 - 0.13 12.5 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Homing endonuclease G-alpha PF00503.20 KNE02821.1 - 9.9e-107 357.1 2.4 1.2e-106 356.9 2.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KNE02821.1 - 2.1e-15 56.6 0.5 3.4e-11 42.9 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KNE02821.1 - 2e-05 24.0 0.2 0.0011 18.4 0.1 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KNE02821.1 - 0.00012 22.2 0.3 0.1 12.9 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KNE02821.1 - 0.0016 18.0 0.0 0.03 13.9 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KNE02821.1 - 0.0052 16.8 0.1 0.56 10.3 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 KNE02821.1 - 0.02 14.5 0.1 0.57 9.8 0.0 2.3 2 0 0 2 2 2 0 Ras family Peptidase_M16_C PF05193.21 KNE02822.1 - 1.2e-18 67.8 0.0 5.1e-18 65.7 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KNE02822.1 - 3.8e-15 56.2 2.5 3.7e-14 53.0 1.0 2.5 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) Ribosomal_S7 PF00177.21 KNE02824.1 - 1.1e-37 129.0 0.6 1.6e-37 128.5 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e RLL PF10036.9 KNE02824.1 - 0.029 14.2 0.1 0.039 13.8 0.1 1.2 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein Flp_C PF05202.12 KNE02824.1 - 0.06 12.9 0.0 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 Recombinase Flp protein PPP4R2 PF09184.11 KNE02825.1 - 1.3e-13 51.2 0.4 1.5e-13 51.0 0.4 1.1 1 0 0 1 1 1 1 PPP4R2 CybS PF05328.12 KNE02826.1 - 3.3e-54 182.2 0.0 4e-54 181.9 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Aminotran_1_2 PF00155.21 KNE02829.1 - 2.2e-70 237.7 0.0 2.5e-70 237.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KNE02829.1 - 2.5e-05 23.0 0.0 4.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KNE02829.1 - 0.00034 19.7 0.0 0.0008 18.5 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KNE02829.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KNE02829.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Methyltransf_16 PF10294.9 KNE02830.1 - 1.4e-15 57.4 0.0 2.7e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KNE02830.1 - 1.7e-07 31.2 0.0 3.2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.16 KNE02831.1 - 2e-30 106.0 39.6 2e-30 106.0 39.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TMEM223 PF14640.6 KNE02831.1 - 0.78 9.9 3.7 11 6.2 0.0 3.3 3 0 0 3 3 3 0 Transmembrane protein 223 DUF1674 PF07896.12 KNE02832.1 - 1.3e-18 67.1 5.0 5.5e-18 65.2 5.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Methyltransf_28 PF02636.17 KNE02833.1 - 2e-78 263.6 0.0 2.5e-78 263.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Metallophos PF00149.28 KNE02834.1 - 2.3e-34 119.7 0.0 3.9e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KNE02834.1 - 4.9e-18 65.3 0.5 1.1e-17 64.2 0.5 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain EF-hand_11 PF08976.11 KNE02835.1 - 0.081 13.8 0.1 0.15 13.0 0.1 1.4 1 0 0 1 1 1 0 EF-hand domain EutA PF06277.11 KNE02835.1 - 0.12 11.1 0.2 0.22 10.3 0.2 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA DUF4407 PF14362.6 KNE02839.1 - 3.7 6.8 7.0 4 6.7 7.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MFS_1 PF07690.16 KNE02841.1 - 8.1e-14 51.3 29.3 2.8e-11 43.0 28.8 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KNE02841.1 - 1.9e-07 29.9 15.4 3.9e-05 22.3 2.1 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Abhydrolase_6 PF12697.7 KNE02842.1 - 3e-14 54.2 0.0 3.7e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNE02842.1 - 3.4e-07 29.8 0.0 4.7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KNE02842.1 - 0.00015 21.5 0.0 0.00026 20.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KNE02842.1 - 0.00024 20.8 0.0 0.00031 20.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase PDDEXK_3 PF13366.6 KNE02842.1 - 0.12 12.8 0.1 0.24 11.8 0.1 1.5 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Pantoate_ligase PF02569.15 KNE02843.1 - 5.9e-91 304.4 0.0 6.7e-91 304.2 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase HA2 PF04408.23 KNE02844.1 - 2.3e-19 69.6 0.0 2.3e-19 69.6 0.0 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KNE02844.1 - 9.5e-18 64.3 0.0 2.5e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KNE02844.1 - 1.3e-15 57.6 0.0 4.1e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KNE02844.1 - 1.5e-09 37.8 0.0 3.6e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KNE02844.1 - 3.2e-06 27.5 0.1 1.6e-05 25.2 0.1 2.2 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KNE02844.1 - 0.00029 20.2 0.0 0.00067 19.0 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KNE02844.1 - 0.0049 17.2 0.1 0.016 15.5 0.1 1.9 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KNE02844.1 - 0.012 14.7 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 KNE02844.1 - 0.016 14.9 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KNE02844.1 - 0.044 13.2 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Flavi_DEAD PF07652.14 KNE02844.1 - 0.057 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain IstB_IS21 PF01695.17 KNE02844.1 - 0.076 12.7 0.0 5.5 6.7 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_14 PF13173.6 KNE02844.1 - 0.085 12.9 0.2 2.2 8.3 0.2 2.7 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KNE02844.1 - 0.098 12.0 1.6 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 KaiC RsgA_GTPase PF03193.16 KNE02844.1 - 0.11 12.4 0.2 0.28 11.1 0.2 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 KNE02844.1 - 0.11 12.1 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KNE02844.1 - 0.12 11.8 0.0 0.41 10.0 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.6 KNE02844.1 - 0.13 12.7 0.6 0.34 11.3 0.0 2.0 2 0 0 2 2 1 0 AAA ATPase domain NACHT PF05729.12 KNE02844.1 - 0.19 11.6 0.6 0.84 9.5 0.6 2.2 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KNE02844.1 - 1.3 9.5 8.9 0.37 11.3 0.1 3.3 3 1 1 4 4 3 0 ABC transporter ResIII PF04851.15 KNE02844.1 - 1.8 8.6 6.9 6.2 6.8 0.0 3.2 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit DUF4651 PF15513.6 KNE02845.1 - 0.059 13.2 0.0 4.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) Nup54 PF13874.6 KNE02846.1 - 1.8e-38 131.8 3.4 7.2e-36 123.4 0.2 2.4 2 0 0 2 2 2 2 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 KNE02846.1 - 2.9e-21 76.1 151.2 6.3e-10 39.8 38.1 5.3 1 1 4 5 5 5 4 Nucleoporin FG repeat region Colipase-like PF15083.6 KNE02847.1 - 0.014 15.5 5.5 0.024 14.8 5.5 1.3 1 0 0 1 1 1 0 Colipase-like HALZ PF02183.18 KNE02847.1 - 0.017 15.3 1.5 0.047 13.9 0.3 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper CHCH PF06747.13 KNE02847.1 - 0.86 9.8 11.2 4.9 7.4 4.9 2.5 2 0 0 2 2 2 0 CHCH domain CX9C PF16860.5 KNE02847.1 - 1.3 9.0 8.0 0.19 11.7 2.3 2.4 2 1 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX6B PF02297.17 KNE02847.1 - 1.4 9.2 11.1 2.2 8.6 4.8 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb COG2 PF06148.11 KNE02849.1 - 4.4e-19 68.9 2.4 7.1e-19 68.2 2.4 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 KNE02849.1 - 5.4e-05 23.2 4.5 0.00039 20.4 0.3 2.7 2 1 1 3 3 3 1 Vps51/Vps67 Zw10 PF06248.13 KNE02849.1 - 0.0041 15.8 0.5 0.006 15.2 0.5 1.1 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Dor1 PF04124.12 KNE02849.1 - 0.0065 15.2 3.7 0.0099 14.6 3.7 1.2 1 0 0 1 1 1 1 Dor1-like family Sec8_exocyst PF04048.14 KNE02849.1 - 0.13 12.2 3.4 0.069 13.0 1.0 1.7 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF4312 PF14189.6 KNE02851.1 - 0.062 13.3 0.3 0.062 13.3 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4312) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Candida_auris-ASM118947v1/GCA_001189475.1_ASM118947v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Candida_auris-ASM118947v1/GCA_001189475.1_ASM118947v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Candida_auris-ASM118947v1/GCA_001189475.1_ASM118947v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Candida_auris-ASM118947v1/GCA_001189475.1_ASM118947v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 15:38:12 2019 # [ok]