# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Transposase_20 PF02371.11 KND95391.1 - 4.7e-22 77.8 0.0 7.2e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DUF3749 PF12568.3 KND95392.1 - 0.012 15.1 0.0 0.014 15.0 0.0 1.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Mastoparan_2 PF08251.6 KND95398.1 - 0.34 11.0 1.5 44 4.5 0.1 3.1 2 0 0 2 2 2 0 Mastoparan peptide PSGP PF07276.6 KND95398.1 - 0.88 9.8 7.7 11 6.4 0.6 2.8 2 0 0 2 2 2 0 Apopolysialoglycoprotein (PSGP) DUF4110 PF13422.1 KND95400.1 - 0.095 12.5 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) TraG_N PF07916.6 KND95404.1 - 6.5 5.0 10.5 2.6 6.3 1.8 2.1 2 0 0 2 2 2 0 TraG-like protein, N-terminal region YTV PF07639.6 KND95405.1 - 1.3 8.8 9.8 5.4 6.8 6.8 2.0 1 1 0 1 1 1 0 YTV MFS_1 PF07690.11 KND95408.1 - 2.9e-38 131.5 21.4 2.9e-38 131.5 14.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily ERGIC_N PF13850.1 KND95408.1 - 0.13 12.2 0.8 0.64 10.0 0.0 2.5 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) EphA2_TM PF14575.1 KND95408.1 - 0.27 11.6 1.3 1.6 9.2 0.0 2.8 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF2207 PF09972.4 KND95408.1 - 2.7 6.4 6.7 2.9 6.3 1.2 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) Fer4 PF00037.22 KND95411.1 - 0.081 12.5 0.7 0.11 12.1 0.5 1.2 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_2 PF12797.2 KND95411.1 - 0.11 12.5 0.5 0.16 11.9 0.4 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain mRNA_triPase PF02940.10 KND95413.1 - 0.14 11.8 5.5 0.16 11.6 3.8 1.2 1 0 0 1 1 1 0 mRNA capping enzyme, beta chain SVA PF05326.6 KND95413.1 - 0.45 10.2 2.3 0.48 10.2 0.9 1.5 1 1 0 1 1 1 0 Seminal vesicle autoantigen (SVA) DUF3416 PF11896.3 KND95413.1 - 0.58 10.0 4.6 0.76 9.6 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3416) DUF3527 PF12043.3 KND95413.1 - 1.5 8.2 13.6 1.8 8.0 9.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) Nucleic_acid_bd PF13820.1 KND95413.1 - 2.4 7.7 9.5 0.63 9.6 1.2 2.2 1 1 1 2 2 2 0 Putative nucleic acid-binding region ECH_C PF13766.1 KND95413.1 - 5.4 7.1 10.5 0.28 11.3 2.2 2.0 1 1 1 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region N_NLPC_P60 PF12912.2 KND95414.1 - 0.14 12.2 0.8 0.15 12.1 0.6 1.0 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term BRCT PF00533.21 KND95415.1 - 6e-27 93.6 2.7 7.1e-07 29.2 0.0 4.7 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KND95415.1 - 4.1e-19 68.1 3.9 1.6e-05 24.6 0.0 5.2 5 0 0 5 5 5 4 twin BRCT domain DUF2009 PF09418.5 KND95418.1 - 0.17 10.6 0.0 0.18 10.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) DUF2462 PF09495.5 KND95421.1 - 4.2e-19 69.0 7.8 4.2e-19 69.0 5.4 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) CTV_P6 PF06706.6 KND95422.1 - 0.0044 16.4 0.4 0.0044 16.4 0.3 1.6 2 0 0 2 2 2 1 Citrus tristeza virus 6-kDa protein O-antigen_lig PF13425.1 KND95422.1 - 0.0082 16.1 0.0 0.0097 15.8 0.0 1.1 1 0 0 1 1 1 1 O-antigen ligase like membrane protein DUF1282 PF06930.7 KND95422.1 - 0.054 13.1 0.3 0.062 12.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) TPX2 PF06886.6 KND95422.1 - 0.088 12.8 0.5 0.13 12.3 0.0 1.5 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) Ferric_reduct PF01794.14 KND95422.1 - 0.097 12.7 1.3 0.11 12.5 0.9 1.1 1 0 0 1 1 1 0 Ferric reductase like transmembrane component Wzz PF02706.10 KND95422.1 - 0.17 11.7 0.4 0.28 10.9 0.3 1.3 1 0 0 1 1 1 0 Chain length determinant protein RNA_pol_Rpb8 PF03870.10 KND95423.1 - 2e-45 154.3 0.1 2.3e-45 154.1 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Mannosyl_trans3 PF11051.3 KND95425.1 - 1.8e-33 116.0 0.0 2.8e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative DUF2470 PF10615.4 KND95427.1 - 3.1e-15 56.1 0.5 7.1e-15 55.0 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2470) Spindle_Spc25 PF08234.7 KND95429.1 - 3.3e-17 62.2 0.6 1.6e-16 60.0 0.0 2.4 2 1 0 2 2 2 1 Chromosome segregation protein Spc25 WEMBL PF05701.6 KND95429.1 - 0.00038 19.0 4.4 0.00038 19.0 3.1 2.0 1 1 1 2 2 2 1 Weak chloroplast movement under blue light TMF_DNA_bd PF12329.3 KND95429.1 - 0.00083 19.1 21.0 0.092 12.5 3.6 2.3 1 1 1 2 2 2 2 TATA element modulatory factor 1 DNA binding Myosin_tail_1 PF01576.14 KND95429.1 - 0.0012 16.7 10.1 0.0015 16.4 7.0 1.2 1 0 0 1 1 1 1 Myosin tail Filament PF00038.16 KND95429.1 - 0.0068 15.9 12.1 0.015 14.8 8.1 1.7 1 1 0 1 1 1 1 Intermediate filament protein IFT57 PF10498.4 KND95429.1 - 0.0078 14.9 11.0 0.011 14.5 7.7 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 CALCOCO1 PF07888.6 KND95429.1 - 0.01 14.2 8.0 0.011 14.1 5.6 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Reo_sigmaC PF04582.7 KND95429.1 - 0.019 14.1 1.0 0.026 13.6 0.7 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 KND95429.1 - 0.02 12.2 12.8 0.025 11.9 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 KND95429.1 - 0.02 13.3 10.3 0.028 12.9 7.1 1.2 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.6 KND95429.1 - 0.028 13.0 14.5 0.19 10.3 10.0 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4618 PF15397.1 KND95429.1 - 0.029 13.7 14.2 0.029 13.6 9.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Bac_GDH PF05088.7 KND95429.1 - 0.036 11.4 6.0 0.043 11.2 4.1 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase DUF3972 PF13118.1 KND95429.1 - 0.054 13.5 8.6 0.084 12.9 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) DUF724 PF05266.9 KND95429.1 - 0.061 12.9 11.8 0.091 12.3 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) HAMP PF00672.20 KND95429.1 - 0.064 13.4 2.0 0.072 13.2 0.1 2.1 2 0 0 2 2 1 0 HAMP domain FlaC_arch PF05377.6 KND95429.1 - 0.065 13.1 4.8 4.1 7.3 0.1 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.7 KND95429.1 - 0.089 13.0 10.2 8 6.7 1.3 3.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1192 PF06698.6 KND95429.1 - 0.092 12.5 0.4 0.092 12.5 0.3 2.4 3 0 0 3 3 1 0 Protein of unknown function (DUF1192) DUF1664 PF07889.7 KND95429.1 - 0.11 12.3 11.5 1.4 8.7 6.4 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.2 KND95429.1 - 0.18 11.6 17.4 0.48 10.2 12.0 1.7 1 1 0 1 1 1 0 Tropomyosin like Fib_alpha PF08702.5 KND95429.1 - 0.27 11.3 11.4 2.7 8.0 6.8 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.4 KND95429.1 - 0.3 10.9 17.1 0.18 11.6 3.1 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.13 KND95429.1 - 0.3 10.8 6.0 2.1 8.1 0.2 3.7 3 1 0 3 3 2 0 Homeobox associated leucine zipper End3 PF12761.2 KND95429.1 - 0.3 10.6 9.3 0.5 9.9 6.5 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 V_ATPase_I PF01496.14 KND95429.1 - 0.31 8.8 7.6 0.38 8.5 5.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 KND95429.1 - 0.36 9.7 10.4 0.49 9.2 7.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 LPP PF04728.8 KND95429.1 - 0.37 10.6 4.8 4.9 7.0 1.1 3.1 1 1 2 3 3 3 0 Lipoprotein leucine-zipper DUF342 PF03961.8 KND95429.1 - 0.4 9.0 8.9 0.55 8.5 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) BLOC1_2 PF10046.4 KND95429.1 - 0.43 10.7 10.2 0.8 9.8 3.8 2.8 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cytochrom_B562 PF07361.6 KND95429.1 - 0.44 10.9 10.4 2.7 8.4 3.4 2.9 1 1 1 3 3 3 0 Cytochrome b562 Snapin_Pallidin PF14712.1 KND95429.1 - 0.47 10.7 11.6 0.82 10.0 1.7 2.6 2 0 0 2 2 2 0 Snapin/Pallidin DUF4201 PF13870.1 KND95429.1 - 0.5 9.7 15.4 1.6 8.1 10.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Rootletin PF15035.1 KND95429.1 - 0.62 10.0 11.8 0.8 9.6 7.7 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Mnd1 PF03962.10 KND95429.1 - 0.62 9.6 13.4 1.1 8.8 8.2 2.0 1 1 1 2 2 2 0 Mnd1 family Ax_dynein_light PF10211.4 KND95429.1 - 0.68 9.7 14.6 1.3 8.8 4.2 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain COG2 PF06148.6 KND95429.1 - 0.86 9.4 10.3 6.5 6.6 0.5 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cortex-I_coil PF09304.5 KND95429.1 - 1 9.4 12.4 2.6 8.1 1.8 2.5 1 1 1 2 2 2 0 Cortexillin I, coiled coil Med10 PF09748.4 KND95429.1 - 1 9.1 7.3 6.1 6.6 1.7 2.5 1 1 1 2 2 2 0 Transcription factor subunit Med10 of Mediator complex DUF3782 PF12644.2 KND95429.1 - 1.2 9.0 9.6 6.6 6.6 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) APG6 PF04111.7 KND95429.1 - 1.2 8.0 11.6 1.9 7.4 8.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 NID PF07292.8 KND95429.1 - 1.3 9.1 5.4 2.6 8.1 0.6 2.9 1 1 2 3 3 3 0 Nmi/IFP 35 domain (NID) SlyX PF04102.7 KND95429.1 - 1.3 9.4 16.0 0.21 11.9 3.1 3.6 2 1 2 4 4 3 0 SlyX bZIP_1 PF00170.16 KND95429.1 - 1.3 8.9 10.7 6.6 6.7 1.7 2.7 2 0 0 2 2 2 0 bZIP transcription factor Seryl_tRNA_N PF02403.17 KND95429.1 - 1.5 8.9 15.3 2.4 8.2 2.3 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MRP-L46 PF11788.3 KND95429.1 - 1.5 9.5 5.6 3.4 8.3 3.9 1.7 1 1 0 1 1 1 0 39S mitochondrial ribosomal protein L46 IncA PF04156.9 KND95429.1 - 1.5 8.3 14.7 1.5 8.4 8.4 1.9 1 1 1 2 2 2 0 IncA protein FliJ PF02050.11 KND95429.1 - 1.6 8.8 17.7 0.074 13.1 4.7 2.7 2 1 1 3 3 2 0 Flagellar FliJ protein Spc24 PF08286.6 KND95429.1 - 1.9 8.2 13.6 3e+02 1.1 9.5 2.5 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DivIC PF04977.10 KND95429.1 - 2.2 7.8 11.5 0.69 9.4 2.3 2.5 1 1 1 2 2 2 0 Septum formation initiator ATG16 PF08614.6 KND95429.1 - 2.7 7.7 14.9 5.9 6.6 8.3 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF1515 PF07439.6 KND95429.1 - 2.7 7.8 5.7 6.7 6.5 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) TPR_MLP1_2 PF07926.7 KND95429.1 - 3.3 7.4 19.2 18 5.0 9.3 3.3 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein TMPIT PF07851.8 KND95429.1 - 4.1 6.3 9.2 3.7 6.5 5.6 1.4 1 1 1 2 2 2 0 TMPIT-like protein Latarcin PF10279.4 KND95429.1 - 4.9 7.4 6.5 33 4.7 4.5 2.2 1 1 0 1 1 1 0 Latarcin precursor ADIP PF11559.3 KND95429.1 - 5.1 6.9 17.7 5.3 6.9 3.8 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Syntaxin-6_N PF09177.6 KND95429.1 - 5.9 7.3 8.5 6.3 7.2 2.1 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal OmpH PF03938.9 KND95429.1 - 6.6 6.6 16.4 1.3 8.9 2.6 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) ACCA PF03255.9 KND95429.1 - 7.2 6.1 9.2 11 5.5 4.2 2.4 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF4094 PF13334.1 KND95429.1 - 7.6 7.0 8.0 1.3 9.4 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) DUF2203 PF09969.4 KND95429.1 - 8.3 6.6 9.3 5.5e+02 0.7 6.5 2.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Spectrin PF00435.16 KND95429.1 - 9.9 6.5 14.5 7 6.9 4.4 2.9 2 1 1 3 3 2 0 Spectrin repeat Exo_endo_phos PF03372.18 KND95430.1 - 2.4e-16 60.4 0.0 3.5e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4405 PF14358.1 KND95430.1 - 0.23 11.6 3.5 6.1 7.0 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) Bacillus_HBL PF05791.6 KND95432.1 - 0.045 13.1 0.5 0.082 12.2 0.2 1.5 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) G-patch PF01585.18 KND95433.1 - 2e-10 40.3 1.5 5.2e-10 38.9 1.1 1.8 1 0 0 1 1 1 1 G-patch domain Peptidase_C54 PF03416.14 KND95434.1 - 1.1e-69 234.6 0.0 1.5e-69 234.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Ssu72 PF04722.8 KND95435.1 - 4.3e-74 248.0 1.0 5.1e-74 247.8 0.7 1.1 1 0 0 1 1 1 1 Ssu72-like protein POP1 PF06978.6 KND95436.1 - 5.1e-40 137.1 1.6 8.2e-40 136.4 1.1 1.3 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 KND95436.1 - 2.2e-19 69.0 0.7 4.3e-19 68.1 0.5 1.5 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.16 KND95436.1 - 0.016 14.5 0.0 0.044 13.1 0.0 1.7 2 0 0 2 2 2 0 Aminomethyltransferase folate-binding domain TRIQK PF15168.1 KND95438.1 - 0.13 12.1 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family BLVR PF06375.6 KND95439.1 - 0.11 12.2 4.9 0.14 12.0 3.4 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Peptidase_S24 PF00717.18 KND95440.1 - 4e-09 35.9 0.0 6.9e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like V-ATPase_H_C PF11698.3 KND95441.1 - 0.1 12.5 0.1 0.17 11.8 0.0 1.4 1 1 0 1 1 1 0 V-ATPase subunit H Elong_Iki1 PF10483.4 KND95442.1 - 1e-71 241.6 0.1 1.2e-71 241.3 0.1 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 HEAT_2 PF13646.1 KND95443.1 - 4e-15 55.8 7.2 0.0049 17.1 1.0 7.8 2 2 5 7 7 7 6 HEAT repeats HEAT_EZ PF13513.1 KND95443.1 - 8.5e-13 48.3 8.0 0.016 15.6 0.0 8.6 9 0 0 9 9 9 4 HEAT-like repeat Adaptin_N PF01602.15 KND95443.1 - 3.4e-07 28.9 2.3 0.00048 18.5 0.0 3.4 1 1 1 3 3 3 2 Adaptin N terminal region HEAT PF02985.17 KND95443.1 - 1.3e-06 27.9 13.0 2.4 8.4 0.0 8.8 8 0 0 8 8 8 1 HEAT repeat NUC173 PF08161.7 KND95443.1 - 7.7e-06 25.3 2.6 0.38 10.0 0.0 4.4 4 1 1 5 5 5 3 NUC173 domain Vac14_Fab1_bd PF12755.2 KND95443.1 - 0.0018 18.6 0.1 6.8 7.1 0.0 4.8 5 1 0 6 6 6 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 KND95443.1 - 0.023 13.4 6.0 0.75 8.4 0.0 3.5 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal Arm PF00514.18 KND95443.1 - 0.46 10.3 10.9 4.3 7.3 0.0 6.0 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat XPG_N PF00752.12 KND95444.1 - 4.8e-34 116.6 0.0 1.8e-33 114.8 0.0 2.1 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KND95444.1 - 1e-26 92.7 0.0 3.4e-26 91.1 0.0 2.0 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 KND95444.1 - 0.00016 21.8 0.5 0.00059 20.0 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.11 KND95444.1 - 0.0059 16.6 0.1 0.027 14.5 0.0 2.1 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family TPX2 PF06886.6 KND95445.1 - 0.91 9.6 9.3 0.096 12.7 1.9 2.9 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) H2TH PF06831.9 KND95447.1 - 1.6e-20 72.6 0.0 3.2e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.19 KND95447.1 - 3.6e-08 33.7 0.0 8.4e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain Pirin_C PF05726.8 KND95447.1 - 0.0079 16.2 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Malic_M PF03949.10 KND95448.1 - 1.2e-74 251.1 0.0 1.8e-74 250.5 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KND95448.1 - 1.3e-61 207.3 0.0 2e-61 206.7 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF2424 PF10340.4 KND95449.1 - 5.8e-31 107.4 0.0 7.8e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 KND95449.1 - 6e-15 55.3 0.0 9.4e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KND95449.1 - 7.5e-05 22.5 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family ADK PF00406.17 KND95450.1 - 6e-61 204.7 0.0 7.7e-61 204.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KND95450.1 - 4.3e-14 51.8 0.0 1e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 KND95450.1 - 2.6e-05 24.1 0.0 4.8e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KND95450.1 - 0.00014 22.6 0.0 0.00026 21.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KND95450.1 - 0.00031 21.0 0.0 0.00081 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KND95450.1 - 0.051 12.6 0.0 0.082 11.9 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 KND95450.1 - 0.077 12.9 0.0 0.14 12.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF1192 PF06698.6 KND95450.1 - 0.095 12.5 0.1 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) CFIA_Pcf11 PF11526.3 KND95451.1 - 4.5e-14 52.3 7.3 4.2e-13 49.2 4.2 2.8 2 1 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 Prok-RING_1 PF14446.1 KND95451.1 - 0.53 10.0 2.9 12 5.7 0.2 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Mito_carr PF00153.22 KND95452.1 - 1.3e-29 101.7 3.1 4.6e-15 55.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein ATP_bind_2 PF03668.10 KND95453.1 - 0.038 13.0 0.5 0.067 12.2 0.0 1.6 2 0 0 2 2 2 0 P-loop ATPase protein family Flocculin_t3 PF13928.1 KND95458.1 - 8.9e-20 70.5 102.8 1.2e-07 31.8 19.0 4.6 4 1 1 5 5 5 3 Flocculin type 3 repeat FANCL_C PF11793.3 KND95458.1 - 0.76 9.7 15.6 4.9 7.1 0.9 3.5 4 0 0 4 4 4 0 FANCL C-terminal domain SapA PF02199.10 KND95458.1 - 4.8 7.0 10.0 45 3.9 0.2 3.7 3 0 0 3 3 3 0 Saposin A-type domain zf-H2C2_2 PF13465.1 KND95459.1 - 0.0071 16.5 0.2 0.0093 16.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger double domain FAD_binding_1 PF00667.15 KND95461.1 - 1e-65 221.2 0.0 1.7e-65 220.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KND95461.1 - 1.6e-09 38.2 0.0 4.5e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 KND95461.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase FAD_binding_6 PF00970.19 KND95461.1 - 0.089 12.9 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain FAD-oxidase_C PF02913.14 KND95462.1 - 2.4e-47 161.3 0.0 3.6e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KND95462.1 - 6.2e-31 106.7 0.1 1.3e-30 105.6 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain YL1_C PF08265.6 KND95463.1 - 2.8e-14 52.3 0.1 5.6e-14 51.4 0.0 1.6 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Sedlin_N PF04628.8 KND95464.1 - 7.3e-22 77.6 0.0 8.5e-22 77.4 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region BAG PF02179.11 KND95466.1 - 9.6e-22 76.8 4.9 9.6e-22 76.8 3.4 1.9 3 0 0 3 3 2 1 BAG domain DUF4094 PF13334.1 KND95466.1 - 0.014 15.7 0.5 0.037 14.4 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Nucleos_tra2_C PF07662.8 KND95466.1 - 0.025 14.0 0.2 0.038 13.4 0.2 1.3 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter C-terminus DUF2373 PF10180.4 KND95466.1 - 0.04 13.4 2.6 0.72 9.4 0.0 3.3 2 2 1 3 3 3 0 Uncharacterised conserved protein (DUF2373) INTS5_N PF14837.1 KND95466.1 - 0.088 12.2 2.9 0.11 11.9 1.7 1.5 1 1 0 1 1 1 0 Integrator complex subunit 5 N-terminus GLTSCR1 PF15249.1 KND95466.1 - 0.15 12.1 2.0 0.19 11.8 0.7 1.7 1 1 1 2 2 2 0 Glioma tumor suppressor candidate region IFT46_B_C PF12317.3 KND95466.1 - 0.17 11.2 6.9 0.11 11.8 2.8 2.1 2 2 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal DUF496 PF04363.7 KND95466.1 - 0.38 10.5 8.7 0.08 12.7 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF496) DUF4375 PF14300.1 KND95466.1 - 0.42 10.6 6.2 0.56 10.1 2.2 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4375) Pkip-1 PF06878.6 KND95466.1 - 0.66 9.8 12.7 0.18 11.7 2.9 2.8 1 1 2 3 3 3 0 Pkip-1 protein Sas10_Utp3 PF04000.10 KND95466.1 - 1.1 9.5 5.1 0.91 9.7 1.3 2.4 2 1 0 2 2 2 0 Sas10/Utp3/C1D family HI0933_like PF03486.9 KND95466.1 - 1.1 7.6 7.5 2.5 6.5 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein ETRAMP PF09716.5 KND95466.1 - 1.6 8.7 6.1 5.6 6.9 4.3 2.2 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Med11 PF10280.4 KND95466.1 - 2.1 8.4 8.7 0.62 10.1 3.2 1.9 2 0 0 2 2 2 0 Mediator complex protein DOPA_dioxygen PF08883.6 KND95467.1 - 1.1e-31 108.9 0.4 1.4e-31 108.6 0.3 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family DnaJ-X PF14308.1 KND95468.1 - 2.5e-61 206.5 14.1 2.5e-61 206.5 9.8 3.5 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 KND95468.1 - 4.6e-25 87.1 1.0 1.4e-24 85.5 0.7 1.9 1 0 0 1 1 1 1 DnaJ domain Ribosomal_S5_C PF03719.10 KND95469.1 - 5.4e-22 76.8 0.0 1.3e-21 75.5 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 KND95469.1 - 6.7e-17 60.9 0.5 1.1e-16 60.2 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DUF2838 PF10998.3 KND95470.1 - 4.5e-38 129.5 12.0 4.5e-38 129.5 8.3 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) PRESAN PF09687.5 KND95470.1 - 0.024 14.6 1.7 0.061 13.3 0.0 2.4 3 0 0 3 3 3 0 Plasmodium RESA N-terminal DUF2802 PF10975.3 KND95470.1 - 0.19 11.5 1.1 0.92 9.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Pox_A_type_inc PF04508.7 KND95470.1 - 0.28 11.0 1.3 0.68 9.8 0.9 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat RRM_1 PF00076.17 KND95471.1 - 1.3e-25 88.8 0.1 1.3e-15 56.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND95471.1 - 3.1e-23 81.5 0.1 5.9e-11 42.1 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND95471.1 - 2.6e-06 27.2 0.0 0.11 12.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ctf8 PF09696.5 KND95471.1 - 0.00076 19.2 0.0 0.00076 19.2 0.0 2.9 3 0 0 3 3 3 1 Ctf8 Nup35_RRM_2 PF14605.1 KND95471.1 - 0.086 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ADH_N PF08240.7 KND95473.1 - 7.6e-31 106.0 1.2 1.3e-30 105.3 0.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KND95473.1 - 3.2e-29 101.1 0.2 5.4e-29 100.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3812 PF12757.2 KND95474.1 - 2.3e-15 56.6 1.1 2.3e-15 56.6 0.8 8.5 5 2 2 7 7 7 1 Protein of unknown function (DUF3812) Reo_sigmaC PF04582.7 KND95474.1 - 0.55 9.3 5.0 1.4 8.0 1.4 2.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Kelch_3 PF13415.1 KND95476.1 - 1.6e-09 37.6 0.1 1.4e-07 31.4 0.0 4.0 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.20 KND95476.1 - 6.1e-09 35.2 0.0 0.00013 21.4 0.0 4.0 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 KND95476.1 - 1.2e-05 25.2 0.0 0.00068 19.7 0.0 3.2 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 KND95476.1 - 1.2e-05 24.9 0.6 0.0048 16.6 0.0 3.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.10 KND95476.1 - 0.00098 18.8 0.7 0.12 12.2 0.1 3.9 2 1 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 KND95476.1 - 0.007 16.2 0.0 2 8.4 0.0 3.0 2 0 0 2 2 2 1 Kelch motif Ank PF00023.25 KND95477.1 - 1.1e-11 43.8 1.3 5.1e-05 22.8 0.1 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 KND95477.1 - 2.6e-09 37.3 0.2 1e-08 35.3 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) TIG PF01833.19 KND95477.1 - 3.1e-09 36.7 0.1 7.2e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 IPT/TIG domain Ank_3 PF13606.1 KND95477.1 - 2.2e-07 30.4 1.2 0.0059 16.7 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KND95477.1 - 9.2e-07 28.9 0.1 9.4e-06 25.7 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 KND95477.1 - 5.6e-06 26.7 1.6 0.00012 22.4 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) YL1 PF05764.8 KND95477.1 - 2.4 7.7 13.3 6.9 6.2 9.2 1.8 1 0 0 1 1 1 0 YL1 nuclear protein HEM4 PF02602.10 KND95478.1 - 2.3e-42 144.8 0.0 2.6e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Antimicrobial17 PF08129.6 KND95478.1 - 0.13 12.0 0.0 0.54 10.0 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta enterocin family AMP-binding PF00501.23 KND95479.1 - 1.4e-91 306.9 0.1 1.8e-91 306.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KND95479.1 - 1.3e-18 67.7 0.3 7.8e-18 65.1 0.2 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain OPA3 PF07047.7 KND95483.1 - 5.9e-35 119.9 2.3 8.7e-35 119.4 1.6 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Striatin PF08232.7 KND95483.1 - 0.00078 19.7 0.1 0.0012 19.1 0.1 1.4 1 0 0 1 1 1 1 Striatin family FimP PF09766.4 KND95483.1 - 0.0072 15.4 1.5 0.0099 14.9 1.0 1.2 1 0 0 1 1 1 1 Fms-interacting protein DUF812 PF05667.6 KND95483.1 - 0.018 13.5 1.4 0.026 13.0 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DivIC PF04977.10 KND95483.1 - 0.023 14.1 2.8 0.025 14.0 1.1 1.8 2 0 0 2 2 2 0 Septum formation initiator ADIP PF11559.3 KND95483.1 - 0.03 14.2 4.5 0.052 13.4 3.1 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Fmp27_WPPW PF10359.4 KND95483.1 - 0.032 12.6 0.4 0.042 12.2 0.3 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TBPIP PF07106.8 KND95483.1 - 0.042 13.4 3.2 0.074 12.6 2.3 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIVA PF05103.8 KND95483.1 - 0.063 13.3 1.5 0.13 12.3 1.0 1.4 1 0 0 1 1 1 0 DivIVA protein DUF1664 PF07889.7 KND95483.1 - 0.085 12.6 1.3 0.15 11.8 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.9 KND95483.1 - 0.11 12.1 1.5 0.17 11.4 1.0 1.3 1 0 0 1 1 1 0 IncA protein ORF6C PF10552.4 KND95483.1 - 0.11 12.1 1.9 0.17 11.6 0.4 1.8 2 0 0 2 2 2 0 ORF6C domain Spc24 PF08286.6 KND95483.1 - 0.12 12.0 3.3 0.22 11.2 2.3 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 THOC7 PF05615.8 KND95483.1 - 0.14 12.4 4.9 0.24 11.6 3.4 1.5 1 1 0 1 1 1 0 Tho complex subunit 7 DUF3573 PF12097.3 KND95483.1 - 0.14 10.7 0.5 0.19 10.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Phage_GP20 PF06810.6 KND95483.1 - 0.15 11.5 4.9 0.12 11.8 2.1 1.7 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF2968 PF11180.3 KND95483.1 - 0.17 11.2 3.4 0.26 10.6 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Ax_dynein_light PF10211.4 KND95483.1 - 0.17 11.6 2.7 0.28 11.0 1.9 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain Ly49 PF08391.5 KND95483.1 - 0.3 11.2 3.1 0.6 10.2 0.7 1.9 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region GrpE PF01025.14 KND95483.1 - 0.52 9.8 4.9 0.86 9.1 3.4 1.3 1 0 0 1 1 1 0 GrpE Cep57_MT_bd PF06657.8 KND95483.1 - 0.75 9.7 5.5 0.32 10.9 1.7 2.0 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Syntaxin PF00804.20 KND95483.1 - 1.2 9.2 6.8 1.5 9.0 3.4 2.0 1 1 0 2 2 2 0 Syntaxin Siah-Interact_N PF09032.6 KND95483.1 - 5.9 7.0 8.3 32 4.6 4.3 2.6 1 1 0 1 1 1 0 Siah interacting protein, N terminal Histone PF00125.19 KND95484.1 - 8.8e-23 80.2 0.1 1.1e-22 79.9 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KND95484.1 - 0.0018 18.3 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone NPR2 PF06218.6 KND95485.1 - 1.3e-177 590.8 1.0 1.6e-177 590.4 0.4 1.3 2 0 0 2 2 2 1 Nitrogen permease regulator 2 NPR3 PF03666.8 KND95485.1 - 0.00013 20.7 5.6 0.0028 16.2 0.0 2.7 3 0 0 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 FAM219A PF15260.1 KND95485.1 - 0.12 12.7 2.2 0.28 11.5 1.5 1.6 1 0 0 1 1 1 0 Protein family FAM219A DUF89 PF01937.14 KND95486.1 - 1.8e-114 382.2 2.7 2.1e-114 382.0 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Zn_clus PF00172.13 KND95488.1 - 1e-10 41.3 9.1 2.1e-10 40.3 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND95488.1 - 9.3e-10 37.8 0.1 1.7e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAT1 PF09770.4 KND95488.1 - 0.13 10.5 36.9 0.19 9.9 25.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cpn60_TCP1 PF00118.19 KND95489.1 - 2.6e-117 392.4 8.8 3e-117 392.2 6.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rrf2 PF02082.15 KND95489.1 - 0.015 15.3 0.1 0.043 13.9 0.1 1.8 1 0 0 1 1 1 0 Transcriptional regulator Capsule_synth PF05159.9 KND95489.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Capsule polysaccharide biosynthesis protein RNA_pol_I_TF PF04090.7 KND95490.1 - 1e-50 171.8 0.4 1.9e-50 170.9 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase I specific initiation factor zf-BED PF02892.10 KND95490.1 - 2.4e-07 30.3 0.6 5.9e-07 29.1 0.4 1.7 1 0 0 1 1 1 1 BED zinc finger zf-RING_2 PF13639.1 KND95491.1 - 6.6e-10 38.6 6.2 1.5e-09 37.5 4.3 1.6 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KND95491.1 - 6.7e-10 38.9 2.8 1.1e-09 38.2 1.9 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KND95491.1 - 1.8e-05 24.3 6.3 0.00012 21.6 4.6 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND95491.1 - 6.2e-05 22.6 3.1 0.00014 21.5 2.2 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KND95491.1 - 8.5e-05 22.5 1.0 8.5e-05 22.5 0.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KND95491.1 - 0.00014 21.5 0.3 0.00034 20.2 0.2 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 KND95491.1 - 0.00031 20.3 4.8 0.00055 19.5 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KND95491.1 - 0.012 15.4 4.1 0.036 13.8 2.9 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KND95491.1 - 0.024 14.4 0.4 0.024 14.4 0.3 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 KND95491.1 - 0.11 12.4 2.1 0.5 10.3 1.5 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Rab5ip PF07019.7 KND95491.1 - 0.17 12.0 5.4 0.37 10.9 0.1 2.8 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) Kinesin PF00225.18 KND95492.1 - 3.7e-92 308.5 0.0 3.7e-92 308.5 0.0 2.3 2 1 1 3 3 3 1 Kinesin motor domain GM_CSF PF01109.12 KND95492.1 - 0.0099 15.8 2.2 0.015 15.2 0.2 2.3 2 0 0 2 2 2 1 Granulocyte-macrophage colony-stimulating factor Apolipoprotein PF01442.13 KND95492.1 - 0.11 11.9 20.9 0.035 13.6 5.6 3.3 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 KND95492.1 - 0.75 9.6 24.5 0.1 12.3 2.6 3.8 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus dsDNA_bind PF01984.15 KND95493.1 - 4.1e-29 100.7 6.2 6.7e-29 100.0 4.3 1.3 1 0 0 1 1 1 1 Double-stranded DNA-binding domain FeoC PF09012.5 KND95493.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator A1_Propeptide PF07966.7 KND95493.1 - 0.16 11.8 0.8 7.1 6.5 0.0 2.4 2 0 0 2 2 2 0 A1 Propeptide Ras PF00071.17 KND95494.1 - 8.6e-44 148.7 0.1 1.1e-43 148.3 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KND95494.1 - 7.6e-09 36.1 0.3 1.5e-08 35.1 0.0 1.7 2 1 1 3 3 3 1 Miro-like protein Arf PF00025.16 KND95494.1 - 1.7e-07 30.6 0.1 2.1e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KND95494.1 - 0.00054 19.4 0.0 0.00073 19.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ribosom_S12_S23 PF00164.20 KND95494.1 - 0.12 11.8 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S12/S23 Metal_resist PF13801.1 KND95495.1 - 0.14 12.1 1.2 0.17 11.8 0.8 1.1 1 0 0 1 1 1 0 Heavy-metal resistance LSM PF01423.17 KND95500.1 - 1.9e-08 33.6 0.3 2.4e-08 33.3 0.2 1.1 1 0 0 1 1 1 1 LSM domain DUF727 PF05303.7 KND95501.1 - 5.1e-08 32.6 0.1 8.8e-05 22.2 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF727) SNF2_assoc PF08455.5 KND95501.1 - 0.063 11.8 0.1 0.063 11.8 0.1 1.1 1 0 0 1 1 1 0 Bacterial SNF2 helicase associated UPF0242 PF06785.6 KND95501.1 - 0.075 11.7 0.0 0.089 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) WBS_methylT PF12589.3 KND95503.1 - 3.3e-16 59.5 6.8 5.8e-16 58.7 4.7 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 KND95503.1 - 2.9e-12 46.9 0.0 5e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND95503.1 - 2.8e-09 37.2 0.0 5.2e-08 33.1 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND95503.1 - 4.4e-08 33.0 0.0 6.5e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND95503.1 - 2.3e-07 31.1 0.0 6.2e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND95503.1 - 3.8e-07 29.7 0.0 7.1e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND95503.1 - 5.5e-06 26.9 0.0 1.5e-05 25.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND95503.1 - 0.00026 21.0 0.0 0.00048 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 KND95503.1 - 0.00087 19.3 0.0 0.0018 18.4 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase CMAS PF02353.15 KND95503.1 - 0.0042 16.1 0.0 0.019 14.0 0.0 1.9 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 KND95503.1 - 0.047 13.2 0.0 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 KND95503.1 - 0.08 12.0 0.1 0.16 11.0 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.9 KND95503.1 - 0.086 11.9 0.0 0.2 10.7 0.0 1.6 2 0 0 2 2 2 0 Tellurite resistance protein TehB N6_N4_Mtase PF01555.13 KND95503.1 - 0.093 12.2 0.1 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 DNA methylase MTS PF05175.9 KND95503.1 - 0.2 11.0 0.7 0.92 8.8 0.1 2.2 2 1 0 2 2 2 0 Methyltransferase small domain MBOAT PF03062.14 KND95504.1 - 1.8e-31 109.4 21.0 1.8e-31 109.4 14.6 3.9 2 2 1 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KND95504.1 - 0.00063 19.7 3.4 0.0034 17.4 2.4 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Peptidase_M76 PF09768.4 KND95505.1 - 1.8e-72 242.3 1.6 2.3e-72 242.0 1.1 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 KND95505.1 - 0.013 15.1 0.7 0.026 14.1 0.3 1.5 1 1 0 1 1 1 0 SprT-like family Tox-MPTase2 PF15638.1 KND95505.1 - 0.04 13.4 0.1 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 2 BSP PF04450.7 KND95505.1 - 0.057 12.8 0.1 0.14 11.6 0.0 1.6 1 1 0 1 1 1 0 Peptidase of plants and bacteria Peptidase_M91 PF14891.1 KND95505.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Effector protein Ank_4 PF13637.1 KND95506.1 - 2.5e-20 72.4 0.7 1.8e-10 41.0 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND95506.1 - 2.7e-18 65.5 0.1 3e-15 55.8 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KND95506.1 - 3.7e-14 51.7 1.3 2.6e-10 39.5 0.2 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 KND95506.1 - 4.1e-14 52.6 0.0 4.2e-13 49.4 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KND95506.1 - 6e-10 38.3 0.1 1.5e-06 27.8 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeat SH3BP5 PF05276.9 KND95506.1 - 0.033 13.4 0.2 0.042 13.1 0.2 1.1 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) DUF533 PF04391.7 KND95506.1 - 0.075 12.4 1.2 8.4 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF533) DUF1682 PF07946.9 KND95507.1 - 4.2e-88 295.2 7.9 4.7e-88 295.1 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Mitofilin PF09731.4 KND95507.1 - 0.0011 17.7 11.0 0.0012 17.6 7.6 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein TCP PF03634.8 KND95507.1 - 0.042 14.2 7.4 0.061 13.6 5.1 1.2 1 0 0 1 1 1 0 TCP family transcription factor Vps5 PF09325.5 KND95507.1 - 0.24 10.6 16.6 0.47 9.6 11.5 1.4 1 0 0 1 1 1 0 Vps5 C terminal like GAGA_bind PF06217.7 KND95507.1 - 0.6 10.0 8.0 0.78 9.6 5.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family APG6 PF04111.7 KND95507.1 - 7.7 5.4 14.4 11 4.8 10.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Stk19 PF10494.4 KND95508.1 - 5.8e-74 248.6 0.2 1.7e-72 243.7 0.0 2.0 2 0 0 2 2 2 2 Serine-threonine protein kinase 19 Mating_N PF12731.2 KND95508.1 - 0.0074 16.1 0.9 0.018 14.9 0.6 1.6 1 0 0 1 1 1 1 Mating-type protein beta 1 DUF4456 PF14644.1 KND95508.1 - 0.13 11.4 0.3 0.22 10.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) Ribosomal_L9_N PF01281.14 KND95509.1 - 1.4e-09 37.0 0.0 2.8e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain zf-HIT PF04438.11 KND95511.1 - 1.2e-09 37.6 6.5 2e-09 36.9 4.5 1.3 1 0 0 1 1 1 1 HIT zinc finger CDC45 PF02724.9 KND95511.1 - 0.013 13.5 3.2 0.018 13.0 2.2 1.2 1 0 0 1 1 1 0 CDC45-like protein AF-4 PF05110.8 KND95511.1 - 0.067 11.0 14.0 0.086 10.7 9.7 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF1610 PF07754.6 KND95511.1 - 0.09 12.9 1.6 0.17 12.0 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) Tnp_zf-ribbon_2 PF13842.1 KND95511.1 - 0.62 10.5 9.4 1.4 9.3 6.5 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon zf-C3HC4_2 PF13923.1 KND95511.1 - 1.8 8.6 9.1 3.4 7.7 6.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 KND95512.1 - 2.9e-35 119.7 0.1 7.2e-18 63.9 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND95512.1 - 8.4e-19 67.3 0.0 1.8e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND95512.1 - 8.5e-17 60.7 0.0 2.1e-07 30.6 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 KND95512.1 - 0.0049 16.3 0.5 0.47 9.9 0.0 2.8 3 0 0 3 3 3 1 Ribonuclease B OB domain Nup35_RRM PF05172.8 KND95512.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif CBS PF00571.23 KND95513.1 - 5.4e-13 48.5 0.0 1.6e-07 30.9 0.0 2.1 2 0 0 2 2 2 2 CBS domain TPX2_importin PF12214.3 KND95513.1 - 0.029 14.4 0.2 0.039 14.0 0.2 1.1 1 0 0 1 1 1 0 Cell cycle regulated microtubule associated protein Rep_Org_C PF06926.6 KND95513.1 - 0.039 14.0 0.3 0.29 11.2 0.3 2.0 1 1 1 2 2 2 0 Putative replisome organiser protein C-terminus Cyt-b5 PF00173.23 KND95514.1 - 1.4e-14 53.6 0.0 3e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 KND95514.1 - 3.7e-11 42.9 17.4 5.2e-11 42.4 10.4 2.2 1 1 1 2 2 2 1 Fatty acid desaturase SWIB PF02201.13 KND95515.1 - 1.3e-08 34.3 1.0 0.00088 18.9 0.0 2.6 2 0 0 2 2 2 2 SWIB/MDM2 domain Ras PF00071.17 KND95518.1 - 6.1e-49 165.5 0.0 7.5e-49 165.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KND95518.1 - 6.9e-15 55.5 0.0 1.3e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KND95518.1 - 1.2e-10 40.9 0.0 1.7e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 KND95518.1 - 0.00062 19.9 0.0 0.0034 17.5 0.0 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 KND95518.1 - 0.001 18.2 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 KND95518.1 - 0.027 13.7 0.1 0.046 13.0 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.15 KND95518.1 - 0.037 12.7 1.6 0.88 8.1 0.1 2.6 2 1 1 3 3 3 0 G-protein alpha subunit AAA_22 PF13401.1 KND95518.1 - 0.066 13.3 0.3 0.23 11.6 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 KND95518.1 - 0.069 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 KND95518.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit zf-U1 PF06220.7 KND95519.1 - 0.022 14.3 6.1 0.083 12.4 4.3 1.9 1 1 0 1 1 1 0 U1 zinc finger ATP_sub_h PF10775.4 KND95520.1 - 4.3e-05 23.1 0.7 5.9e-05 22.7 0.5 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h Hormone_3 PF00159.13 KND95520.1 - 0.087 12.8 0.1 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Pancreatic hormone peptide ADIP PF11559.3 KND95521.1 - 2.7e-27 95.5 13.6 2.7e-27 95.5 9.5 3.1 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding DUF2400 PF09674.5 KND95521.1 - 0.034 13.8 3.0 0.07 12.8 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) DUF1759 PF03564.10 KND95521.1 - 0.052 13.3 11.8 1.2 8.9 1.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) Syntaxin-6_N PF09177.6 KND95521.1 - 0.12 12.7 16.3 4 7.9 0.0 4.3 3 2 1 4 4 4 0 Syntaxin 6, N-terminal ArdA PF07275.6 KND95521.1 - 1.3 9.2 6.1 0.3 11.2 0.4 2.5 3 1 1 4 4 4 0 Antirestriction protein (ArdA) IncA PF04156.9 KND95521.1 - 1.5 8.3 23.1 0.26 10.8 6.2 3.2 3 0 0 3 3 3 0 IncA protein BLOC1_2 PF10046.4 KND95521.1 - 2.6 8.2 25.6 0.18 11.9 3.5 4.4 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Adenylsucc_synt PF00709.16 KND95521.1 - 2.9 6.4 6.9 1.4 7.4 1.6 2.1 1 1 0 2 2 2 0 Adenylosuccinate synthetase HAUS-augmin3 PF14932.1 KND95521.1 - 3.4 6.7 23.1 2.1 7.4 7.1 2.9 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 Troponin PF00992.15 KND95521.1 - 4.5 7.3 18.3 0.76 9.8 1.6 2.9 2 1 1 3 3 3 0 Troponin CENP-Q PF13094.1 KND95521.1 - 7.2 6.6 21.7 0.043 13.8 5.0 3.1 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1664 PF07889.7 KND95521.1 - 8.8 6.1 11.8 4.1 7.2 3.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Peptidase_S76 PF13611.1 KND95522.1 - 0.015 15.4 0.7 0.027 14.5 0.5 1.4 1 0 0 1 1 1 0 Serine peptidase of plant viral polyprotein, P1 MCM PF00493.18 KND95523.1 - 5.8e-139 462.4 0.1 7.9e-139 462.0 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KND95523.1 - 1.2e-22 80.6 1.8 1.7e-22 80.1 0.5 1.8 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KND95523.1 - 1.6e-06 27.4 0.0 0.00074 18.7 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KND95523.1 - 1.3e-05 24.8 0.0 3.9e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KND95523.1 - 0.0014 18.2 0.0 0.0077 15.8 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KND95523.1 - 0.022 14.2 0.1 0.4 10.1 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.24 KND95523.1 - 0.053 13.7 0.1 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Prefoldin PF02996.12 KND95524.1 - 2.1e-27 95.1 5.8 2.4e-27 94.9 4.0 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 KND95524.1 - 0.0044 16.7 3.1 0.0044 16.7 2.2 2.1 1 1 1 2 2 2 1 Prefoldin subunit DUF4358 PF14270.1 KND95524.1 - 0.028 14.2 1.6 0.037 13.9 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) ORF6C PF10552.4 KND95524.1 - 0.15 11.7 2.2 0.25 11.0 0.2 2.0 2 0 0 2 2 2 0 ORF6C domain Syntaxin-6_N PF09177.6 KND95524.1 - 0.33 11.3 3.7 0.36 11.2 0.3 2.2 1 1 0 2 2 2 0 Syntaxin 6, N-terminal SlyX PF04102.7 KND95524.1 - 0.56 10.6 3.3 0.74 10.2 0.2 2.2 2 0 0 2 2 2 0 SlyX Ribosomal_L18e PF00828.14 KND95526.1 - 3.3e-16 59.8 0.1 5.9e-16 59.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 DHC_N2 PF08393.8 KND95527.1 - 2.7e-100 335.7 7.8 2.7e-100 335.7 5.4 4.6 3 1 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KND95527.1 - 3.1e-66 223.1 0.0 9.9e-66 221.5 0.0 1.9 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N1 PF08385.7 KND95527.1 - 1.4e-63 215.1 26.2 1.4e-63 215.1 18.2 3.6 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 Dynein_heavy PF03028.10 KND95527.1 - 4.3e-50 170.5 0.3 4.3e-50 170.5 0.2 2.0 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor AAA_8 PF12780.2 KND95527.1 - 4e-31 107.9 1.5 1.3e-30 106.2 0.2 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.2 KND95527.1 - 4.5e-27 94.7 7.8 7.5e-27 93.9 5.4 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 KND95527.1 - 1.4e-25 89.6 0.0 1.3e-10 41.1 0.0 6.0 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_9 PF12781.2 KND95527.1 - 5.8e-23 80.9 0.1 1.6e-22 79.4 0.1 1.8 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 KND95527.1 - 4.2e-21 75.2 0.0 3.1e-20 72.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA PF00004.24 KND95527.1 - 1.9e-16 60.4 7.1 1.7e-05 25.0 0.0 6.8 7 0 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KND95527.1 - 1.1e-15 57.8 0.0 0.0032 17.6 0.0 7.1 6 0 0 6 6 5 4 AAA domain T2SE PF00437.15 KND95527.1 - 7.3e-09 34.9 1.3 0.12 11.2 0.0 3.9 4 0 0 4 4 4 3 Type II/IV secretion system protein AAA_18 PF13238.1 KND95527.1 - 7.9e-09 35.9 0.2 0.51 10.6 0.0 5.9 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 KND95527.1 - 2.2e-08 34.9 1.0 0.33 11.7 0.0 6.0 5 0 0 5 5 5 1 AAA domain AAA_16 PF13191.1 KND95527.1 - 6.8e-06 26.1 8.5 3.5 7.5 0.0 6.7 7 0 0 7 7 6 2 AAA ATPase domain AAA_33 PF13671.1 KND95527.1 - 1.5e-05 24.8 5.1 0.79 9.5 0.0 5.6 6 0 0 6 6 5 1 AAA domain AAA_19 PF13245.1 KND95527.1 - 1.7e-05 24.4 1.5 1.1 9.0 0.0 4.6 4 0 0 4 4 4 1 Part of AAA domain Zeta_toxin PF06414.7 KND95527.1 - 2.8e-05 23.3 1.1 0.86 8.6 0.0 4.2 5 0 0 5 5 5 2 Zeta toxin AAA_29 PF13555.1 KND95527.1 - 0.00011 21.6 0.1 0.44 10.1 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_30 PF13604.1 KND95527.1 - 0.00019 21.1 0.1 1.1 8.7 0.1 4.6 5 0 0 5 5 5 1 AAA domain AAA_25 PF13481.1 KND95527.1 - 0.00057 19.3 0.0 0.48 9.8 0.0 4.1 3 0 0 3 3 3 1 AAA domain cobW PF02492.14 KND95527.1 - 0.0037 16.7 2.1 0.17 11.2 0.1 3.2 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 KND95527.1 - 0.004 16.7 1.5 1.9 8.1 0.0 4.1 4 0 0 4 4 4 1 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 KND95527.1 - 0.013 14.9 0.0 11 5.4 0.0 4.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family Mg_chelatase PF01078.16 KND95527.1 - 0.018 14.2 6.0 0.88 8.6 0.0 4.1 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 KND95527.1 - 0.091 12.4 2.8 9.4 5.9 0.1 3.7 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KND95527.1 - 0.4 10.9 9.9 2 8.7 0.0 5.0 5 0 0 5 5 3 0 ABC transporter SMC_N PF02463.14 KND95527.1 - 6.6 5.9 6.4 35 3.5 0.0 4.1 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain Mpv17_PMP22 PF04117.7 KND95528.1 - 1.7e-20 72.3 5.9 4.8e-20 70.9 4.2 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.7 KND95529.1 - 3.4e-26 90.6 6.3 5e-26 90.1 4.4 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family B56 PF01603.15 KND95531.1 - 6.4e-152 505.9 16.9 9.8e-143 475.6 9.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) TetR_C_2 PF08361.6 KND95531.1 - 0.047 13.6 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region IMPDH PF00478.20 KND95532.1 - 2.4e-28 99.0 0.0 2.5e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KND95532.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 CBS domain NMO PF03060.10 KND95532.1 - 0.085 11.9 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Nitronate monooxygenase IMPDH PF00478.20 KND95533.1 - 2.4e-109 365.4 0.3 2.8e-109 365.2 0.2 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KND95533.1 - 1.3e-08 34.0 1.8 8.8e-08 31.3 1.3 2.1 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 KND95533.1 - 5.2e-06 25.8 1.3 5.2e-06 25.8 0.9 1.6 2 0 0 2 2 2 1 Nitronate monooxygenase ThiG PF05690.9 KND95533.1 - 7.1e-05 21.9 1.1 0.00022 20.3 0.2 1.9 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 KND95533.1 - 9.3e-05 21.8 0.5 0.00061 19.1 0.3 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein NanE PF04131.9 KND95533.1 - 0.002 17.0 0.0 0.0044 16.0 0.0 1.5 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase EAL PF00563.15 KND95533.1 - 0.011 15.1 0.1 0.81 9.1 0.0 2.3 2 0 0 2 2 2 0 EAL domain CBS PF00571.23 KND95533.1 - 0.017 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 CBS domain Aldolase PF01081.14 KND95533.1 - 0.018 14.1 0.2 0.06 12.4 0.0 1.9 3 0 0 3 3 3 0 KDPG and KHG aldolase B12-binding PF02310.14 KND95533.1 - 0.093 12.6 0.2 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 B12 binding domain DUF1273 PF06908.6 KND95533.1 - 0.096 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) CH PF00307.26 KND95534.1 - 6.7e-10 38.9 0.0 9.2e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF2247 PF10004.4 KND95534.1 - 0.11 12.2 0.6 0.16 11.6 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) DUF1322 PF07032.6 KND95535.1 - 0.035 14.2 0.0 0.057 13.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1322) Ribosomal_L28e PF01778.12 KND95536.1 - 1.8e-29 102.4 0.5 1.8e-29 102.4 0.4 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 KND95536.1 - 5e-29 100.3 14.2 5e-29 100.3 9.8 2.6 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.5 KND95536.1 - 0.01 14.9 16.6 0.014 14.5 11.5 1.3 1 0 0 1 1 1 0 BUD22 Ribosomal_L24e PF01246.15 KND95536.1 - 0.1 12.4 0.1 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein L24e CENP-T PF15511.1 KND95536.1 - 0.24 10.6 11.4 0.31 10.2 7.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 KND95536.1 - 2.4 5.9 27.4 3.3 5.5 19.0 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.7 KND95536.1 - 5.5 5.2 27.1 7.2 4.8 18.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RTA1 PF04479.8 KND95537.1 - 2.5e-49 167.8 11.9 2.9e-49 167.6 5.9 2.4 2 1 0 2 2 2 1 RTA1 like protein ERGIC_N PF13850.1 KND95537.1 - 0.069 13.1 0.3 0.38 10.7 0.0 2.3 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF2207 PF09972.4 KND95537.1 - 4.9 5.6 7.2 0.49 8.9 0.0 2.5 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) KilA-N PF04383.8 KND95538.1 - 0.00037 20.0 0.0 0.017 14.7 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain DUF504 PF04457.7 KND95538.1 - 0.067 13.3 0.1 0.14 12.3 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF504) SymE_toxin PF08845.5 KND95538.1 - 0.12 12.2 0.1 11 5.9 0.0 2.4 2 0 0 2 2 2 0 Toxin SymE, type I toxin-antitoxin system Aa_trans PF01490.13 KND95540.1 - 4.1e-51 173.7 32.0 4.8e-51 173.5 22.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RRM_1 PF00076.17 KND95542.1 - 7.7e-14 51.0 2.0 7.8e-05 22.2 0.0 4.5 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND95542.1 - 2.2e-11 43.5 2.1 5.8e-07 29.4 0.0 4.0 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND95542.1 - 3.8e-09 36.2 3.5 0.0012 18.6 0.1 3.9 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BTV_NS2 PF04514.7 KND95542.1 - 0.91 8.3 12.7 1.5 7.5 8.8 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Sugar_tr PF00083.19 KND95543.1 - 1e-83 281.4 22.0 1.2e-83 281.1 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND95543.1 - 1.6e-27 96.1 31.3 4.6e-24 84.7 15.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HpaB PF03241.8 KND95544.1 - 0.11 11.2 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Glyco_hydro_3 PF00933.16 KND95546.1 - 1.1e-69 234.7 0.0 1.7e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KND95546.1 - 2.8e-53 180.7 0.0 4.6e-53 180.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KND95546.1 - 1.1e-19 70.0 0.2 2.6e-19 68.8 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KND95546.1 - 0.00028 20.5 0.0 0.00055 19.5 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Pertussis_S2S3 PF02918.10 KND95546.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain BRAP2 PF07576.7 KND95547.1 - 0.085 12.4 0.4 0.12 11.9 0.3 1.4 1 1 0 1 1 1 0 BRCA1-associated protein 2 FMN_dh PF01070.13 KND95549.1 - 5.2e-111 370.9 0.0 7.1e-111 370.4 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KND95549.1 - 1.8e-22 78.9 0.1 1.2e-21 76.2 0.0 2.3 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KND95549.1 - 1.8e-10 40.3 0.2 2.7e-10 39.7 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 KND95549.1 - 9.9e-05 21.7 0.3 0.24 10.6 0.0 2.4 2 0 0 2 2 2 2 Histidine biosynthesis protein IMPDH PF00478.20 KND95549.1 - 0.00026 19.9 0.8 0.00061 18.7 0.1 1.8 1 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KND95549.1 - 0.00046 19.4 0.2 0.00071 18.8 0.2 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Peptidase_M19 PF01244.16 KND95549.1 - 0.024 13.5 0.0 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) ThiG PF05690.9 KND95549.1 - 0.068 12.2 1.3 6.1 5.8 0.0 2.5 1 1 2 3 3 3 0 Thiazole biosynthesis protein ThiG UDPGP PF01704.13 KND95554.1 - 3.8e-188 625.2 0.0 4.4e-188 625.0 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NAPRTase PF04095.11 KND95556.1 - 8.3e-61 205.3 0.0 1.1e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family IBN_N PF03810.14 KND95557.1 - 3.6e-17 62.0 0.7 3e-16 59.0 0.1 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain CtaG_Cox11 PF04442.9 KND95558.1 - 2.7e-50 170.0 0.5 3.2e-50 169.8 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 PPTA PF01239.17 KND95559.1 - 1.5e-29 100.0 15.7 1.7e-09 36.5 0.1 5.0 5 0 0 5 5 5 4 Protein prenyltransferase alpha subunit repeat GST_N_2 PF13409.1 KND95560.1 - 3e-10 39.9 0.1 5.8e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KND95560.1 - 1.3e-08 34.6 0.0 2.9e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KND95560.1 - 4.6e-08 33.1 0.0 8e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KND95560.1 - 1.9e-07 31.1 0.0 4.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KND95560.1 - 1.4e-06 28.6 0.0 2.1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KND95560.1 - 2.6e-06 27.2 0.0 4.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Coprogen_oxidas PF01218.13 KND95560.1 - 0.12 10.9 0.1 0.32 9.5 0.0 1.6 2 0 0 2 2 2 0 Coproporphyrinogen III oxidase TauD PF02668.11 KND95561.1 - 5.4e-48 163.8 0.9 1.5e-47 162.4 0.2 1.7 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_transf_15 PF01793.11 KND95562.1 - 3.2e-120 401.0 17.0 3.9e-120 400.7 11.8 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase OPT PF03169.10 KND95563.1 - 7.2e-138 460.7 46.9 8.2e-138 460.5 32.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein tRNA-synt_2 PF00152.15 KND95564.1 - 3e-111 371.4 0.0 3.7e-111 371.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KND95564.1 - 0.00019 21.1 0.0 0.00036 20.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 KND95564.1 - 0.00035 20.2 0.6 0.0061 16.1 0.4 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 KND95564.1 - 0.0028 16.8 0.1 0.015 14.5 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) PUF PF00806.14 KND95565.1 - 5.7e-24 82.2 0.1 0.0002 20.6 0.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat GST_C PF00043.20 KND95566.1 - 1.2e-10 41.1 0.0 2e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KND95566.1 - 1.1e-06 28.3 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KND95566.1 - 2.9e-05 24.4 0.0 5.2e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_S2 PF00318.15 KND95566.1 - 0.13 11.5 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S2 NOB1_Zn_bind PF08772.6 KND95567.1 - 2.6e-28 97.6 1.6 4.9e-28 96.7 1.1 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Zn-ribbon_8 PF09723.5 KND95567.1 - 0.0017 18.2 2.6 0.0037 17.1 1.8 1.5 1 0 0 1 1 1 1 Zinc ribbon domain AF1Q PF15017.1 KND95567.1 - 0.013 15.3 8.0 0.013 15.3 5.5 2.5 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Phage_CP76 PF06892.6 KND95567.1 - 0.019 14.2 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) zf-RING_3 PF14369.1 KND95567.1 - 0.3 11.1 1.5 0.62 10.1 1.0 1.5 1 0 0 1 1 1 0 zinc-finger EF-hand_4 PF12763.2 KND95568.1 - 4.5e-05 23.1 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.1 KND95568.1 - 0.016 14.8 0.0 0.073 12.6 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair HDA2-3 PF11496.3 KND95569.1 - 7.3e-59 199.0 2.5 1.7e-58 197.8 1.7 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 HSP70 PF00012.15 KND95569.1 - 0.23 9.3 9.9 0.43 8.4 6.9 1.4 1 0 0 1 1 1 0 Hsp70 protein DUF4164 PF13747.1 KND95569.1 - 4.9 7.3 17.7 0.65 10.1 2.7 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) SlyX PF04102.7 KND95569.1 - 7.4 7.0 10.1 57 4.1 3.1 3.7 1 1 2 3 3 3 0 SlyX Pyridoxal_deC PF00282.14 KND95570.1 - 2.3e-20 72.3 0.0 3.4e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.12 KND95570.1 - 1e-08 34.6 0.0 1.6e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KND95570.1 - 4.3e-07 29.0 0.0 2.1e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KND95570.1 - 7.5e-05 21.8 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KND95570.1 - 0.0084 14.4 0.0 0.013 13.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF436 PF04260.7 KND95570.1 - 0.086 12.3 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF436) PQ-loop PF04193.9 KND95572.1 - 1.6e-17 62.8 0.2 3.2e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 PQ loop repeat MtN3_slv PF03083.11 KND95572.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 Sugar efflux transporter for intercellular exchange MAP65_ASE1 PF03999.7 KND95574.1 - 1.7e-43 149.2 21.5 1.7e-43 149.2 14.9 2.6 3 1 0 3 3 3 1 Microtubule associated protein (MAP65/ASE1 family) SFTA2 PF15210.1 KND95574.1 - 4 7.1 7.8 7.8 6.1 0.1 3.7 3 0 0 3 3 3 0 Surfactant-associated protein 2 MMR_HSR1 PF01926.18 KND95575.1 - 6.1e-17 61.6 0.1 1.6e-14 53.8 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KND95575.1 - 2.2e-06 27.0 0.3 2.3e-05 23.7 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B DUF258 PF03193.11 KND95575.1 - 0.00072 18.7 0.2 0.003 16.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 KND95575.1 - 0.0048 17.3 0.3 0.11 12.9 0.0 2.7 2 1 0 2 2 2 1 Miro-like protein AIG1 PF04548.11 KND95575.1 - 0.0064 15.6 0.1 0.017 14.2 0.0 1.7 1 0 0 1 1 1 1 AIG1 family Arf PF00025.16 KND95575.1 - 0.017 14.4 1.1 0.017 14.4 0.8 2.7 3 0 0 3 3 3 0 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KND95575.1 - 0.03 13.4 0.1 0.095 11.8 0.1 1.8 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Dynamin_N PF00350.18 KND95575.1 - 1.1 9.1 6.7 0.22 11.3 0.7 2.8 2 1 1 3 3 3 0 Dynamin family AAA PF00004.24 KND95575.1 - 1.6 8.9 4.4 17 5.5 0.1 3.0 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) AA_permease PF00324.16 KND95579.1 - 1.3e-17 63.3 0.2 1.4e-17 63.2 0.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND95579.1 - 0.00078 18.0 0.4 0.00084 17.9 0.3 1.0 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 KND95580.1 - 1.3e-07 30.6 39.1 2.2e-05 23.3 25.4 3.2 1 1 0 1 1 1 1 Major Facilitator Superfamily FmdA_AmdA PF03069.10 KND95583.1 - 8.4e-146 485.3 0.0 9.6e-146 485.1 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family DUF2161 PF09929.4 KND95583.1 - 0.089 12.7 0.3 0.23 11.3 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2161) Toprim_4 PF13662.1 KND95584.1 - 0.063 13.2 0.0 0.079 12.9 0.0 1.2 1 0 0 1 1 1 0 Toprim domain Flocculin_t3 PF13928.1 KND95585.1 - 5.4e-07 29.6 70.6 0.00061 19.8 8.6 4.9 3 1 1 4 4 4 3 Flocculin type 3 repeat CFEM PF05730.6 KND95585.1 - 0.3 10.9 0.1 0.3 10.9 0.1 4.3 2 1 0 2 2 2 0 CFEM domain Transp_cyt_pur PF02133.10 KND95586.1 - 6.6e-67 225.9 33.2 8.2e-67 225.6 23.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF681 PF05080.7 KND95586.1 - 0.024 15.0 0.0 0.064 13.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF681) DUF1352 PF07086.7 KND95586.1 - 0.56 9.8 7.2 3.5 7.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1352) Peptidase_C14 PF00656.17 KND95588.1 - 9.1e-77 258.0 0.0 1.2e-76 257.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain adh_short_C2 PF13561.1 KND95589.1 - 2.6e-24 86.3 0.1 3.3e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KND95589.1 - 8.2e-21 74.6 2.8 1.1e-20 74.1 1.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND95589.1 - 1.8e-09 37.5 0.6 2.5e-09 37.0 0.4 1.2 1 0 0 1 1 1 1 KR domain PDZ PF00595.19 KND95589.1 - 0.033 14.3 0.3 0.059 13.5 0.2 1.4 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) CoA_binding_2 PF13380.1 KND95589.1 - 0.065 13.3 0.2 0.13 12.4 0.2 1.4 1 0 0 1 1 1 0 CoA binding domain Glyco_tran_WecB PF03808.8 KND95589.1 - 0.11 11.9 0.1 0.31 10.4 0.1 1.7 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family DUF1977 PF09320.6 KND95591.1 - 1.1e-31 109.2 1.9 6.6e-31 106.7 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 KND95591.1 - 6.1e-27 93.1 0.9 1.2e-26 92.1 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain DUF2427 PF10348.4 KND95591.1 - 0.022 14.3 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) NST1 PF13945.1 KND95593.1 - 0.14 12.2 4.4 0.17 11.9 3.1 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Asp PF00026.18 KND95594.1 - 1.2e-67 228.3 3.8 4.3e-60 203.6 0.9 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 KND95594.1 - 3e-05 24.0 1.6 0.0026 17.7 0.2 3.1 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KND95594.1 - 3.1e-05 24.3 0.1 1.2 9.6 0.0 3.5 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 KND95594.1 - 0.0024 17.4 0.0 0.016 14.7 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal HAMP PF00672.20 KND95596.1 - 6.4e-40 135.1 12.2 6.1e-10 39.1 0.0 6.3 6 0 0 6 6 6 5 HAMP domain HATPase_c PF02518.21 KND95596.1 - 4e-28 97.3 0.1 1.1e-27 95.9 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KND95596.1 - 3.3e-26 91.4 0.4 6.5e-25 87.3 0.1 2.7 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KND95596.1 - 4.4e-19 68.2 2.5 3e-18 65.5 0.4 3.1 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain DUF1693 PF07984.7 KND95596.1 - 0.24 10.5 6.7 12 4.8 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1693) DUF2365 PF10157.4 KND95596.1 - 4.1 7.2 21.9 7.3 6.4 0.1 6.7 5 1 0 7 7 7 0 Uncharacterized conserved protein (DUF2365) DNA_pol_B PF00136.16 KND95597.1 - 3.3e-146 487.7 3.8 4.4e-146 487.3 2.6 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KND95597.1 - 5.2e-84 281.8 0.6 1.1e-83 280.8 0.4 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KND95597.1 - 5.7e-23 80.6 10.8 1.3e-22 79.5 7.5 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 KND95597.1 - 0.00069 19.4 0.3 0.037 13.8 0.1 3.1 2 1 0 2 2 2 1 RNase_H superfamily DNA_pol_B_2 PF03175.8 KND95597.1 - 0.00076 18.2 0.5 0.02 13.6 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.4 KND95597.1 - 0.0099 15.4 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Med5 PF08689.5 KND95598.1 - 6.7e-83 279.0 30.5 8.3e-83 278.6 21.1 1.1 1 0 0 1 1 1 1 Mediator complex subunit Med5 Pex14_N PF04695.8 KND95600.1 - 2.3e-40 137.8 0.2 2.3e-40 137.8 0.1 3.5 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CCDC84 PF14968.1 KND95600.1 - 0.00039 20.0 7.4 0.00039 20.0 5.1 1.7 1 1 0 1 1 1 1 Coiled coil protein 84 Mitofilin PF09731.4 KND95600.1 - 0.0029 16.3 1.8 0.0029 16.3 1.2 2.1 1 1 1 2 2 2 1 Mitochondrial inner membrane protein CR6_interact PF10147.4 KND95600.1 - 0.0064 15.8 0.1 0.0064 15.8 0.0 2.8 2 1 0 2 2 2 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Mt_ATP-synt_D PF05873.7 KND95600.1 - 0.014 15.0 2.9 0.033 13.8 2.0 1.6 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Tox-WTIP PF15654.1 KND95600.1 - 0.037 13.6 0.2 0.037 13.6 0.1 2.1 2 0 0 2 2 2 0 Toxin with a conserved tryptophan and TIP tripeptide motif TORC_C PF12886.2 KND95600.1 - 0.083 13.0 2.3 0.22 11.7 1.6 1.8 1 0 0 1 1 1 0 Transducer of regulated CREB activity, C terminus DUF1664 PF07889.7 KND95600.1 - 0.34 10.7 7.4 4.5 7.0 4.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-C4H2 PF10146.4 KND95600.1 - 1.5 8.8 23.2 1.4 8.9 9.0 2.7 2 1 1 3 3 3 0 Zinc finger-containing protein NPV_P10 PF05531.7 KND95600.1 - 2.7 8.2 11.7 2.8 8.2 0.5 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Mito_carr PF00153.22 KND95602.1 - 1.7e-47 159.0 1.6 1.4e-15 56.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Prenyltrans PF00432.16 KND95603.1 - 6e-23 80.0 1.3 3.2e-05 23.4 0.0 5.8 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KND95603.1 - 8.9e-11 42.1 0.0 0.00043 20.6 0.0 4.2 1 1 4 5 5 5 3 Prenyltransferase-like ACPS PF01648.15 KND95604.1 - 3.9e-09 36.3 0.1 1.3e-08 34.6 0.0 1.8 1 1 1 2 2 2 1 4'-phosphopantetheinyl transferase superfamily DUF4206 PF13901.1 KND95604.1 - 0.1 12.1 0.5 0.2 11.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) Beta_elim_lyase PF01212.16 KND95605.1 - 4.1e-75 252.6 0.0 5.3e-75 252.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KND95605.1 - 1.1e-06 27.8 0.0 1.6e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aldedh PF00171.17 KND95607.1 - 2.4e-177 589.9 4.5 2.8e-177 589.7 3.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KND95607.1 - 1.3e-06 27.4 0.1 2e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KND95607.1 - 0.0011 18.2 0.7 0.0056 15.9 0.5 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) F-box-like PF12937.2 KND95608.1 - 5e-05 22.9 0.2 0.00015 21.4 0.1 1.9 1 0 0 1 1 1 1 F-box-like DUF1706 PF08020.6 KND95610.1 - 0.048 13.1 3.6 0.092 12.2 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) DUF966 PF06136.8 KND95610.1 - 2.1 7.6 20.5 3.2 7.0 14.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Vezatin PF12632.2 KND95611.1 - 1.4e-11 43.9 4.3 1.4e-11 43.9 3.0 1.8 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes SNF2_N PF00176.18 KND95612.1 - 3.1e-70 236.3 2.3 5.7e-70 235.4 1.6 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 KND95612.1 - 7.7e-51 171.8 21.5 7.7e-51 171.8 14.9 2.4 2 0 0 2 2 2 1 DNA-binding domain Helicase_C PF00271.26 KND95612.1 - 3.4e-13 49.2 0.0 9.4e-13 47.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Tmemb_14 PF03647.8 KND95614.1 - 1.1e-25 89.7 3.7 1.3e-25 89.5 2.6 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2416 PF10315.4 KND95614.1 - 0.1 12.8 1.5 0.14 12.4 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2416) SASP PF00269.15 KND95615.1 - 0.4 10.5 2.5 0.7 9.7 1.6 1.6 1 1 0 1 1 1 0 Small, acid-soluble spore proteins, alpha/beta type Ribosomal_S3_C PF00189.15 KND95616.1 - 5.4e-15 55.3 0.2 1.1e-14 54.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 KND95616.1 - 3.9e-09 35.9 0.3 8e-09 34.9 0.2 1.6 1 0 0 1 1 1 1 KH domain GATase_5 PF13507.1 KND95617.1 - 5.7e-97 323.6 0.0 9.1e-97 322.9 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 KND95617.1 - 7e-46 156.0 2.1 5.1e-25 88.2 0.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 KND95617.1 - 2.8e-24 85.1 0.2 1.2e-23 83.2 0.0 2.2 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Synaptobrevin PF00957.16 KND95619.1 - 6.2e-27 93.0 1.3 6.8e-27 92.9 0.9 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF1100 PF06500.6 KND95619.1 - 0.036 12.6 0.0 0.039 12.5 0.0 1.0 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) MtrG PF04210.8 KND95619.1 - 3.2 7.4 8.6 11 5.7 5.9 1.8 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G GCV_H PF01597.14 KND95620.1 - 4.5e-41 139.3 0.4 5.6e-41 139.0 0.3 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 KND95620.1 - 0.017 14.7 0.2 0.037 13.6 0.1 1.5 1 0 0 1 1 1 0 Biotin-requiring enzyme RnfC_N PF13375.1 KND95620.1 - 0.055 13.1 0.1 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain IucA_IucC PF04183.7 KND95620.1 - 0.089 12.0 0.1 0.47 9.6 0.1 2.0 1 1 1 2 2 2 0 IucA / IucC family NPFF PF15085.1 KND95621.1 - 0.1 12.8 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Neuropeptide FF HSP70 PF00012.15 KND95622.1 - 2.9e-269 894.1 8.0 3.2e-269 893.9 5.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KND95622.1 - 1.2e-14 53.7 0.1 5.5e-13 48.2 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 KND95622.1 - 0.0014 18.2 0.0 0.0028 17.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 KND95622.1 - 0.051 12.4 1.1 1 8.1 0.0 2.5 3 0 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain Na_Ca_ex PF01699.19 KND95623.1 - 3.4e-34 117.4 40.0 5.8e-19 68.0 7.6 3.1 3 0 0 3 3 3 2 Sodium/calcium exchanger protein AAA PF00004.24 KND95625.1 - 5.5e-98 324.2 0.0 5.6e-48 162.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KND95625.1 - 4.2e-18 65.0 0.7 1.4e-17 63.3 0.2 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 KND95625.1 - 4e-14 52.8 0.0 1.5e-07 31.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KND95625.1 - 1.9e-13 50.0 0.0 6.4e-06 25.3 0.0 2.9 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KND95625.1 - 3.9e-12 46.0 0.6 5.1e-06 26.2 0.0 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KND95625.1 - 4.8e-12 45.9 0.0 2.7e-06 27.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KND95625.1 - 9.5e-12 45.8 0.0 0.00015 22.5 0.0 3.5 3 0 0 3 3 2 2 AAA domain CDC48_2 PF02933.12 KND95625.1 - 6.1e-11 41.8 0.0 1.5e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 KND95625.1 - 1.6e-10 41.2 2.8 0.0037 17.3 0.1 4.8 3 2 1 4 4 4 2 AAA domain AAA_16 PF13191.1 KND95625.1 - 1.7e-09 37.9 0.5 0.004 17.1 0.0 4.0 3 2 0 3 3 2 2 AAA ATPase domain TIP49 PF06068.8 KND95625.1 - 2.3e-09 36.4 0.1 0.00083 18.1 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 KND95625.1 - 2.4e-08 33.9 0.0 0.0013 18.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KND95625.1 - 3.9e-08 32.9 0.9 0.0047 16.3 0.0 3.3 4 0 0 4 4 3 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 KND95625.1 - 2e-07 30.2 0.1 0.0042 16.1 0.0 2.9 4 0 0 4 4 2 2 Zeta toxin RNA_helicase PF00910.17 KND95625.1 - 3.9e-07 30.1 0.0 0.03 14.5 0.0 3.5 4 0 0 4 4 2 2 RNA helicase Mg_chelatase PF01078.16 KND95625.1 - 4e-07 29.3 0.5 0.026 13.7 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KND95625.1 - 1.3e-06 27.9 6.9 0.044 13.1 0.2 4.3 2 2 1 4 4 4 2 AAA domain AAA_19 PF13245.1 KND95625.1 - 2.2e-06 27.3 1.4 0.029 14.1 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain ResIII PF04851.10 KND95625.1 - 3.9e-06 26.8 0.2 0.0026 17.6 0.0 2.6 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit KaiC PF06745.8 KND95625.1 - 4.4e-06 25.9 1.7 0.4 9.7 0.1 3.5 2 1 1 3 3 3 2 KaiC AAA_18 PF13238.1 KND95625.1 - 5e-06 26.8 0.0 0.15 12.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 KND95625.1 - 5.8e-06 26.6 0.1 0.073 13.3 0.0 4.1 3 1 0 3 3 3 1 ABC transporter AAA_28 PF13521.1 KND95625.1 - 1.7e-05 24.8 0.0 0.23 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 KND95625.1 - 2.8e-05 23.6 0.1 0.15 11.5 0.0 3.4 3 1 0 3 3 2 1 Sigma-54 interaction domain AAA_24 PF13479.1 KND95625.1 - 3.3e-05 23.5 0.0 0.18 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.5 KND95625.1 - 6e-05 22.8 0.1 0.0009 19.0 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain PhoH PF02562.11 KND95625.1 - 7.4e-05 22.0 2.0 0.065 12.4 0.0 2.8 3 0 0 3 3 3 2 PhoH-like protein Sigma54_activ_2 PF14532.1 KND95625.1 - 7.7e-05 22.7 0.0 0.39 10.7 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KND95625.1 - 8.9e-05 21.4 0.1 0.35 9.7 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.13 KND95625.1 - 0.00012 21.8 0.0 0.1 12.2 0.0 3.4 3 1 0 3 3 3 1 Bacterial dnaA protein DUF815 PF05673.8 KND95625.1 - 0.00015 20.7 0.0 0.2 10.5 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 KND95625.1 - 0.00016 21.4 1.2 0.78 9.3 0.1 4.2 3 2 2 5 5 5 2 Archaeal ATPase AAA_11 PF13086.1 KND95625.1 - 0.00016 21.3 0.0 0.62 9.6 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_3 PF07726.6 KND95625.1 - 0.00026 20.6 0.0 0.94 9.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KND95625.1 - 0.00064 19.4 0.3 3.7 7.1 0.0 3.5 3 0 0 3 3 3 0 NACHT domain AAA_30 PF13604.1 KND95625.1 - 0.0014 18.2 0.0 1.9 7.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 KND95625.1 - 0.0015 17.5 0.0 1.6 7.6 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 KND95625.1 - 0.0062 15.4 0.3 2.8 6.7 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain T2SE PF00437.15 KND95625.1 - 0.0075 15.1 0.0 2 7.2 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein NTPase_1 PF03266.10 KND95625.1 - 0.0077 15.9 1.1 3.4 7.3 0.0 4.0 4 0 0 4 4 4 0 NTPase IPT PF01745.11 KND95625.1 - 0.014 14.6 0.2 1.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.9 KND95625.1 - 0.037 13.0 0.0 2.3 7.0 0.0 2.7 2 1 1 3 3 3 0 KAP family P-loop domain AAA_10 PF12846.2 KND95625.1 - 0.042 13.2 1.5 11 5.3 0.1 3.7 3 1 1 4 4 4 0 AAA-like domain KTI12 PF08433.5 KND95625.1 - 0.059 12.5 0.0 6.3 5.9 0.0 2.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 UPF0079 PF02367.12 KND95625.1 - 0.061 12.9 0.1 9.1 5.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 KND95625.1 - 0.073 12.5 0.0 14 5.1 0.0 2.9 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase FliL PF03748.9 KND95626.1 - 0.052 13.5 0.0 0.054 13.5 0.0 1.0 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL ABC2_membrane PF01061.19 KND95627.1 - 2.1e-85 285.1 45.8 1.8e-44 151.4 8.7 3.2 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 KND95627.1 - 7.8e-41 139.5 0.0 5.3e-19 68.8 0.0 2.9 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 KND95627.1 - 2.2e-35 120.4 5.5 3.4e-33 113.3 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 KND95627.1 - 1.4e-24 85.9 0.0 3.3e-24 84.7 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KND95627.1 - 4.4e-09 36.0 0.0 0.00011 21.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KND95627.1 - 1.3e-07 30.9 0.0 6.3e-05 22.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 KND95627.1 - 4.9e-07 29.0 31.0 0.00079 18.5 11.4 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.1 KND95627.1 - 3.9e-06 26.2 0.7 0.00074 19.0 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KND95627.1 - 1.5e-05 25.0 0.9 0.00075 19.5 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KND95627.1 - 2e-05 25.3 0.0 0.012 16.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KND95627.1 - 2.3e-05 24.2 0.0 0.25 11.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KND95627.1 - 4.2e-05 23.2 0.1 0.092 12.5 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain SMC_N PF02463.14 KND95627.1 - 0.00022 20.5 0.0 0.1 11.8 0.0 3.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KND95627.1 - 0.00035 20.7 0.0 0.27 11.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KND95627.1 - 0.00048 20.4 0.0 0.024 14.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KND95627.1 - 0.00065 19.6 0.4 0.013 15.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KND95627.1 - 0.0007 19.0 1.0 0.052 12.9 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 KND95627.1 - 0.0014 18.6 0.0 0.21 11.5 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.7 KND95627.1 - 0.0018 17.9 0.2 0.17 11.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.1 KND95627.1 - 0.0019 18.2 2.4 0.049 13.5 0.0 3.6 4 0 0 4 4 3 1 AAA domain ABC_ATPase PF09818.4 KND95627.1 - 0.0024 16.5 0.1 0.018 13.6 0.0 2.0 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_30 PF13604.1 KND95627.1 - 0.0043 16.6 0.0 0.12 11.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KND95627.1 - 0.0054 16.3 0.4 0.081 12.5 0.1 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 KND95627.1 - 0.0074 16.6 0.3 0.1 12.9 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 KND95627.1 - 0.0074 15.7 0.1 4.4 6.6 0.1 2.8 3 0 0 3 3 3 1 AAA-like domain Arch_ATPase PF01637.13 KND95627.1 - 0.042 13.5 0.0 3.8 7.1 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase PduV-EutP PF10662.4 KND95627.1 - 0.12 11.8 0.5 0.41 10.1 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 KND95627.1 - 0.12 12.8 0.0 13 6.3 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Zeta_toxin PF06414.7 KND95627.1 - 0.14 11.2 0.1 0.74 8.8 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.10 KND95627.1 - 0.23 11.1 0.2 2.2 7.9 0.0 2.5 3 0 0 3 3 3 0 NTPase YCII PF03795.9 KND95628.1 - 2.8e-06 27.4 0.0 4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain AAA_2 PF07724.9 KND95630.1 - 4.4e-46 156.9 2.0 2.1e-44 151.4 0.0 3.3 4 0 0 4 4 3 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KND95630.1 - 4.3e-23 81.9 0.2 1.4e-12 47.9 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KND95630.1 - 1.5e-21 76.0 0.5 5.4e-21 74.2 0.4 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 KND95630.1 - 3.1e-14 52.8 0.0 1.7e-08 34.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.15 KND95630.1 - 8.9e-13 47.9 1.0 2.4e-09 36.9 0.2 3.4 3 0 0 3 3 3 2 Clp amino terminal domain Sigma54_activat PF00158.21 KND95630.1 - 2.5e-12 46.6 0.6 7.5e-07 28.7 0.0 3.3 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.1 KND95630.1 - 1.8e-10 41.1 12.1 1.6e-05 25.0 0.1 5.1 4 2 2 6 6 5 2 AAA ATPase domain AAA_22 PF13401.1 KND95630.1 - 4.7e-09 36.4 0.2 0.011 15.9 0.0 3.7 2 1 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 KND95630.1 - 8.3e-07 28.9 3.7 0.0037 16.9 1.5 4.3 3 1 0 3 3 3 1 Archaeal ATPase Mg_chelatase PF01078.16 KND95630.1 - 0.00045 19.4 0.0 2 7.5 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KND95630.1 - 0.00069 19.3 0.0 0.12 11.9 0.0 2.8 2 0 0 2 2 2 1 NACHT domain DUF258 PF03193.11 KND95630.1 - 0.0028 16.8 0.0 0.08 12.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KND95630.1 - 0.0031 17.4 0.4 0.15 11.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.6 KND95630.1 - 0.0051 16.4 0.0 0.18 11.4 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 KND95630.1 - 0.007 16.0 0.0 1.7 8.3 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 KND95630.1 - 0.012 15.0 0.0 0.59 9.5 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_tran PF00005.22 KND95630.1 - 0.019 15.2 0.1 10 6.4 0.0 3.1 2 0 0 2 2 2 0 ABC transporter Torsin PF06309.6 KND95630.1 - 0.02 14.7 0.0 0.18 11.7 0.0 2.5 3 0 0 3 3 2 0 Torsin AAA_18 PF13238.1 KND95630.1 - 0.021 15.1 4.6 4.3 7.6 0.1 3.9 3 1 1 4 4 3 0 AAA domain SRP54 PF00448.17 KND95630.1 - 0.021 14.2 0.0 0.79 9.1 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 KND95630.1 - 0.027 13.5 3.3 0.24 10.4 0.0 3.6 4 0 0 4 4 4 0 Zeta toxin AAA_29 PF13555.1 KND95630.1 - 0.029 13.9 0.1 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Nup54 PF13874.1 KND95630.1 - 0.032 13.9 4.0 0.12 12.0 2.7 2.0 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 AAA_17 PF13207.1 KND95630.1 - 0.038 14.7 13.4 0.47 11.2 0.0 4.1 3 1 0 3 3 3 0 AAA domain APS_kinase PF01583.15 KND95630.1 - 0.051 13.2 0.7 0.29 10.7 0.0 2.6 3 1 1 4 4 3 0 Adenylylsulphate kinase AAA_24 PF13479.1 KND95630.1 - 0.054 13.0 0.0 10 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KND95630.1 - 0.066 12.0 0.4 4.6 6.0 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain PduV-EutP PF10662.4 KND95630.1 - 0.12 11.8 1.5 12 5.4 0.0 3.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 KND95630.1 - 0.24 10.7 3.7 1.3 8.4 0.1 3.0 2 2 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 KND95630.1 - 0.54 10.4 1.6 23 5.1 0.0 3.3 4 0 0 4 4 2 0 RNA helicase IncA PF04156.9 KND95630.1 - 8.6 5.8 13.2 1.5 8.3 6.1 1.9 2 0 0 2 2 2 0 IncA protein eIF-6 PF01912.13 KND95631.1 - 9.9e-86 285.9 0.6 1.2e-85 285.6 0.4 1.1 1 0 0 1 1 1 1 eIF-6 family Phage_holin_6 PF10746.4 KND95631.1 - 0.027 14.1 0.4 0.061 13.0 0.0 1.7 2 0 0 2 2 2 0 Phage holin family 6 TRP PF06011.7 KND95633.1 - 2.4e-155 517.4 33.1 2.4e-155 517.4 22.9 1.8 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KND95633.1 - 2.5e-41 141.0 3.0 5.6e-41 139.8 2.1 1.6 1 0 0 1 1 1 1 ML-like domain DUF4612 PF15389.1 KND95634.1 - 0.091 13.3 0.2 0.15 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) MARVEL PF01284.18 KND95636.1 - 3.3e-08 33.4 15.3 4.6e-08 32.9 10.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain Cyto_ox_2 PF02322.10 KND95636.1 - 0.018 14.2 8.5 0.024 13.8 5.9 1.1 1 0 0 1 1 1 0 Cytochrome oxidase subunit II 7tm_2 PF00002.19 KND95636.1 - 0.025 13.6 10.1 0.04 12.9 7.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) SCAMP PF04144.8 KND95636.1 - 2.1 8.2 15.2 0.046 13.6 1.7 2.1 1 1 1 2 2 2 0 SCAMP family DUF1129 PF06570.6 KND95636.1 - 7.3 5.8 7.1 5.9 6.1 3.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) 2-oxoacid_dh PF00198.18 KND95637.1 - 1.6e-79 266.4 0.1 2.2e-79 265.9 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KND95637.1 - 1.6e-19 69.3 3.5 2.7e-19 68.5 2.4 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.14 KND95637.1 - 2.1e-05 24.2 1.0 6e-05 22.7 0.5 1.9 2 0 0 2 2 2 1 Glycine cleavage H-protein Biotin_lipoyl_2 PF13533.1 KND95637.1 - 0.00015 21.3 1.3 0.0015 18.1 0.3 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.1 KND95637.1 - 0.0045 17.3 1.2 0.1 12.9 0.2 2.4 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.1 KND95637.1 - 0.0046 16.6 0.3 0.033 13.9 0.1 2.2 1 1 1 2 2 2 1 RnfC Barrel sandwich hybrid domain CMV_1a PF12467.3 KND95637.1 - 0.15 12.4 10.1 3.9 7.8 5.2 2.4 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family Vfa1 PF08432.5 KND95637.1 - 0.21 11.6 12.4 0.35 10.8 8.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1510 PF07423.6 KND95637.1 - 0.43 9.9 13.2 0.66 9.3 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CT47 PF15623.1 KND95637.1 - 0.63 9.7 20.0 0.94 9.1 13.9 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 DDHD PF02862.12 KND95637.1 - 0.7 9.6 4.3 1.1 9.0 3.0 1.3 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 KND95637.1 - 0.88 9.4 17.5 1.3 8.8 12.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.7 KND95637.1 - 1 9.2 6.9 1.4 8.7 4.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family YqfQ PF14181.1 KND95637.1 - 1.8 8.5 13.5 3.7 7.5 9.3 1.6 1 0 0 1 1 1 0 YqfQ-like protein MCPVI PF02993.9 KND95637.1 - 2.9 7.9 6.4 5.5 7.0 4.4 1.6 1 0 0 1 1 1 0 Minor capsid protein VI zf-C2H2 PF00096.21 KND95638.1 - 1.1e-11 44.3 24.2 3.6e-05 23.8 2.6 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND95638.1 - 1e-09 38.0 19.1 0.00087 19.4 0.5 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KND95638.1 - 3.1e-08 33.4 18.9 3.7e-06 26.9 0.4 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KND95638.1 - 2.3e-05 24.3 5.1 0.018 15.1 0.3 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 KND95638.1 - 0.02 15.2 1.5 0.02 15.2 1.0 2.2 1 1 2 3 3 3 0 TRAF-type zinc finger zf-C2H2_4 PF13894.1 KND95639.1 - 1e-09 38.0 12.1 0.00011 22.3 0.6 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KND95639.1 - 1.4e-09 37.6 17.8 3e-05 24.0 0.9 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KND95639.1 - 9.4e-09 35.1 19.0 2.1e-07 30.8 4.0 3.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 KND95639.1 - 0.00074 19.3 4.5 0.002 17.9 0.2 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.7 KND95639.1 - 0.0011 19.0 3.8 0.0038 17.3 2.6 2.0 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 KND95639.1 - 0.038 13.7 9.4 0.19 11.4 2.3 2.5 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.3 KND95639.1 - 0.076 13.1 7.6 0.043 13.9 1.0 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KND95639.1 - 0.079 13.1 7.9 1.7 8.9 0.3 3.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 KND95639.1 - 3 7.6 9.4 2.9 7.6 0.1 2.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Kelch_4 PF13418.1 KND95640.1 - 9.6e-06 25.2 1.9 0.69 9.7 0.1 3.9 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 KND95640.1 - 5.5e-05 23.1 7.3 0.0039 17.3 0.1 4.8 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 KND95640.1 - 0.0062 16.0 2.3 1.7 8.2 0.0 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 KND95640.1 - 0.0086 16.2 3.1 1 9.6 0.1 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Chorismate_synt PF01264.16 KND95641.1 - 2.7e-134 447.0 0.0 3.1e-134 446.8 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase SRPRB PF09439.5 KND95642.1 - 1.1e-31 109.4 0.1 1.5e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 KND95642.1 - 1.1e-07 31.2 0.0 2.1e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KND95642.1 - 2.2e-06 27.2 0.1 9.4e-06 25.1 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KND95642.1 - 2.8e-06 27.2 0.0 4.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KND95642.1 - 5.5e-05 22.8 1.0 0.0034 16.9 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Miro PF08477.8 KND95642.1 - 0.00019 21.9 0.1 0.00036 21.0 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KND95642.1 - 0.00052 19.2 0.4 0.00094 18.3 0.2 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_23 PF13476.1 KND95642.1 - 0.0078 16.5 1.5 0.016 15.5 0.1 2.0 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.13 KND95642.1 - 0.0088 15.3 0.1 0.023 13.9 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B NACHT PF05729.7 KND95642.1 - 0.016 14.8 0.5 0.33 10.5 0.3 2.5 1 1 0 1 1 1 0 NACHT domain AAA_21 PF13304.1 KND95642.1 - 0.017 15.1 0.4 0.033 14.1 0.2 1.5 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 KND95642.1 - 0.04 13.3 0.1 0.72 9.2 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 KND95642.1 - 0.089 12.2 0.4 0.58 9.6 0.2 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 KND95642.1 - 0.1 12.1 0.1 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Vfa1 PF08432.5 KND95643.1 - 2.9e-46 157.7 9.6 3.3e-46 157.6 6.6 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF342 PF03961.8 KND95643.1 - 0.62 8.4 3.1 0.77 8.0 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DivIVA PF05103.8 KND95643.1 - 0.63 10.1 5.8 0.25 11.4 1.2 2.0 2 0 0 2 2 2 0 DivIVA protein MBD PF01429.14 KND95646.1 - 0.022 14.2 0.8 0.028 13.9 0.6 1.1 1 0 0 1 1 1 0 Methyl-CpG binding domain Metallophos PF00149.23 KND95647.1 - 1.5e-44 151.8 0.2 1.8e-44 151.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Aminotran_1_2 PF00155.16 KND95649.1 - 7.5e-78 262.0 0.0 8.4e-78 261.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Esterase PF00756.15 KND95649.1 - 0.074 12.4 0.0 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 Putative esterase EMP24_GP25L PF01105.19 KND95651.1 - 2.4e-46 157.7 0.3 2.9e-46 157.5 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3753 PF12575.3 KND95651.1 - 0.27 11.0 0.1 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Pkinase PF00069.20 KND95653.1 - 7.1e-47 159.7 0.0 8.4e-47 159.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND95653.1 - 3.9e-16 58.8 0.0 5.8e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND95653.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF2406 PF10295.4 KND95654.1 - 4.6e-23 81.4 0.6 1.1e-22 80.2 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) TPR_11 PF13414.1 KND95657.1 - 4.8e-09 35.7 0.5 1.3e-08 34.3 0.1 1.9 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KND95657.1 - 7e-07 28.6 0.3 0.034 13.7 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KND95657.1 - 8e-06 25.3 0.0 0.37 10.8 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KND95657.1 - 1.5e-05 24.8 0.1 0.0017 18.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KND95657.1 - 0.00041 19.9 1.4 0.098 12.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KND95657.1 - 0.0015 18.7 0.0 0.0039 17.4 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KND95657.1 - 0.027 14.3 0.1 0.53 10.1 0.0 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat DnaJ PF00226.26 KND95657.1 - 0.052 13.2 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 DnaJ domain Trypan_PARP PF05887.6 KND95657.1 - 3.1 7.6 19.5 2.2 8.0 2.7 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Nop10p PF04135.7 KND95658.1 - 4e-22 77.6 0.1 5e-22 77.3 0.1 1.2 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family DASH_Dad4 PF08650.5 KND95659.1 - 1.5e-28 98.5 3.4 1.6e-28 98.3 2.3 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 MMS22L_N PF14910.1 KND95659.1 - 0.036 12.3 0.2 0.04 12.1 0.1 1.0 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, N-terminal DASH_Duo1 PF08651.5 KND95659.1 - 0.21 11.1 2.3 0.27 10.8 1.6 1.1 1 0 0 1 1 1 0 DASH complex subunit Duo1 Zn_clus PF00172.13 KND95660.1 - 2.2e-08 33.8 8.8 3.6e-08 33.1 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KND95661.1 - 2.7e-26 92.1 29.1 5.1e-19 68.2 3.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KND95661.1 - 1.1e-05 24.0 9.8 1.1e-05 24.0 6.8 2.3 2 1 0 2 2 2 1 MFS/sugar transport protein ATG22 PF11700.3 KND95661.1 - 2.6e-05 22.9 11.2 2.6e-05 22.9 7.8 2.3 2 1 1 3 3 3 1 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 KND95661.1 - 0.001 18.8 0.3 0.03 14.1 0.2 3.0 2 0 0 2 2 2 1 MFS_1 like family TRI12 PF06609.8 KND95661.1 - 0.006 14.8 0.5 0.006 14.8 0.3 1.8 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) AA_permease PF00324.16 KND95663.1 - 2.6e-113 378.9 47.6 3.2e-113 378.6 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND95663.1 - 2.2e-39 135.1 51.9 2.6e-39 134.9 36.0 1.0 1 0 0 1 1 1 1 Amino acid permease VASP_tetra PF08776.6 KND95663.1 - 0.11 11.8 1.1 0.17 11.2 0.8 1.3 1 0 0 1 1 1 0 VASP tetramerisation domain DUF3767 PF12597.3 KND95663.1 - 0.17 11.5 0.5 0.48 10.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3767) PQ-loop PF04193.9 KND95665.1 - 0.097 12.2 0.6 0.15 11.6 0.4 1.3 1 0 0 1 1 1 0 PQ loop repeat Acetyltransf_7 PF13508.1 KND95666.1 - 0.00019 21.4 0.2 0.00061 19.9 0.2 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-C2H2 PF00096.21 KND95667.1 - 4.6e-12 45.5 19.1 4.4e-06 26.7 2.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND95667.1 - 8.6e-09 35.1 15.0 0.0095 16.2 1.0 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KND95667.1 - 1e-08 35.0 17.8 3.3e-06 27.1 1.3 4.8 4 1 0 4 4 4 3 Zinc-finger double domain Med15 PF09606.5 KND95667.1 - 0.00077 17.8 44.6 0.0011 17.3 30.9 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal zf-C2H2_jaz PF12171.3 KND95667.1 - 0.0031 17.6 0.9 0.0031 17.6 0.6 3.8 4 0 0 4 4 3 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 KND95667.1 - 0.02 14.5 1.2 1.9 8.2 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.1 KND95667.1 - 0.029 14.2 3.9 0.15 12.0 0.3 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.2 KND95667.1 - 0.51 10.6 5.7 1.7 8.9 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type PAT1 PF09770.4 KND95667.1 - 1.6 6.9 49.1 2.1 6.5 34.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CpXC PF14353.1 KND95667.1 - 1.8 8.5 6.7 0.52 10.2 0.3 2.5 2 0 0 2 2 2 0 CpXC protein TFIIA PF03153.8 KND95667.1 - 3.8 7.3 24.5 5 6.9 17.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-BED PF02892.10 KND95667.1 - 4.6 7.0 7.0 4.6 7.0 0.3 3.1 3 0 0 3 3 3 0 BED zinc finger Suf PF05843.9 KND95667.1 - 6.1 6.4 15.2 11 5.6 10.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Granulin PF00396.13 KND95668.1 - 0.027 14.5 1.2 0.05 13.7 0.8 1.4 1 0 0 1 1 1 0 Granulin Carn_acyltransf PF00755.15 KND95672.1 - 4.7e-91 305.6 0.1 7.3e-91 305.0 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase GCV_T PF01571.16 KND95673.1 - 9.7e-06 25.0 0.0 0.02 14.2 0.0 2.7 3 0 0 3 3 3 2 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KND95673.1 - 0.0081 16.1 0.1 0.033 14.1 0.0 1.9 1 1 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain CRAL_TRIO PF00650.15 KND95674.1 - 5.4e-37 126.7 0.1 8.1e-37 126.1 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KND95674.1 - 6.9e-12 45.3 1.0 2.2e-11 43.6 0.3 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KND95674.1 - 9.9e-05 22.2 0.0 0.00019 21.3 0.0 1.4 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Glyco_hydro_56 PF01630.13 KND95674.1 - 0.12 10.9 0.8 0.22 10.0 0.5 1.4 1 1 0 1 1 1 0 Hyaluronidase RasGAP PF00616.14 KND95675.1 - 1.8e-55 187.6 3.2 1.8e-55 187.6 2.2 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 KND95675.1 - 1.2e-05 25.0 0.1 2.8e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 C2 domain Tom22 PF04281.8 KND95675.1 - 0.15 11.5 4.6 0.85 9.1 1.6 2.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 UPF1_Zn_bind PF09416.5 KND95678.1 - 3.7e-61 205.1 7.2 3.7e-61 205.1 5.0 2.4 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 KND95678.1 - 2.3e-56 190.3 0.0 4.1e-56 189.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KND95678.1 - 1.9e-51 174.9 0.2 3.1e-51 174.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND95678.1 - 4.8e-14 51.8 1.1 2.4e-13 49.6 0.4 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KND95678.1 - 2.2e-13 50.2 0.1 3e-12 46.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KND95678.1 - 1.6e-05 24.8 0.0 2.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KND95678.1 - 0.00012 21.6 0.1 1.4 8.3 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 KND95678.1 - 0.00016 20.7 0.0 0.01 14.8 0.0 3.0 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 KND95678.1 - 0.0023 17.2 0.1 0.078 12.2 0.0 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 KND95678.1 - 0.0028 17.3 0.0 0.0057 16.3 0.0 1.5 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 KND95678.1 - 0.0035 16.3 0.1 0.37 9.7 0.0 2.4 2 0 0 2 2 2 1 PIF1-like helicase DEAD PF00270.24 KND95678.1 - 0.0084 15.6 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.11 KND95678.1 - 0.013 14.7 0.0 0.036 13.3 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein FtsK_SpoIIIE PF01580.13 KND95678.1 - 0.013 15.0 0.1 0.035 13.5 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family Flavi_DEAD PF07652.9 KND95678.1 - 0.022 14.5 0.4 0.043 13.5 0.3 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_16 PF13191.1 KND95678.1 - 0.032 14.2 0.5 0.078 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 KND95678.1 - 0.052 12.4 0.0 0.093 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Ribosomal_S13_N PF08069.7 KND95678.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain KaiC PF06745.8 KND95678.1 - 0.2 10.7 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 KaiC PHD PF00628.24 KND95678.1 - 1.6 8.5 7.6 0.43 10.3 2.6 2.1 2 0 0 2 2 2 0 PHD-finger RRN3 PF05327.6 KND95683.1 - 0.15 10.1 4.2 0.17 9.9 2.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 MCPVI PF02993.9 KND95683.1 - 0.5 10.4 4.2 0.68 10.0 2.9 1.2 1 0 0 1 1 1 0 Minor capsid protein VI DUF4366 PF14283.1 KND95683.1 - 1 8.7 7.9 1.4 8.2 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) SspB PF04386.8 KND95683.1 - 1.3 8.5 6.8 8.5 5.9 4.9 1.9 2 0 0 2 2 2 0 Stringent starvation protein B DUF4492 PF14899.1 KND95684.1 - 0.054 12.9 1.2 0.065 12.7 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) Flocculin_t3 PF13928.1 KND95698.1 - 1.6 8.9 33.8 0.11 12.7 4.2 2.5 2 0 0 2 2 2 0 Flocculin type 3 repeat UQ_con PF00179.21 KND95701.1 - 5.8e-45 152.1 0.0 6.6e-45 151.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KND95701.1 - 0.00017 21.3 0.0 0.00021 21.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KND95701.1 - 0.048 13.3 0.0 0.11 12.1 0.0 1.7 1 1 0 1 1 1 0 UEV domain CRCB PF02537.10 KND95704.1 - 2.2e-31 108.1 28.3 2.4e-21 75.7 7.2 2.7 2 1 1 3 3 3 2 CrcB-like protein Phage_holin_3 PF05106.7 KND95704.1 - 8.3 6.4 8.4 0.67 9.9 0.6 2.7 2 1 0 2 2 2 0 Phage holin family (Lysis protein S) Hydrolase_like2 PF13246.1 KND95706.1 - 6.5e-15 54.8 0.2 2.7e-14 52.8 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 KND95706.1 - 1.5e-13 50.3 0.0 4.3e-13 48.8 0.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 KND95706.1 - 1.5e-12 48.0 0.3 5.5e-12 46.2 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KND95706.1 - 7.7e-10 39.5 0.7 1e-07 32.5 0.5 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KND95706.1 - 0.0014 18.2 0.5 0.0045 16.6 0.3 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Mito_carr PF00153.22 KND95710.1 - 6.8e-69 227.6 6.6 5.3e-25 86.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SAM_decarbox PF01536.11 KND95712.1 - 3.2e-93 312.0 0.0 3.2e-92 308.7 0.0 1.9 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase Pkinase PF00069.20 KND95717.1 - 6.2e-62 209.0 0.0 8.4e-62 208.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND95717.1 - 8.4e-31 106.9 0.0 1.3e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND95717.1 - 1.2e-06 27.7 0.0 2.1e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 KND95717.1 - 0.0016 18.9 0.9 0.0046 17.4 0.6 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Dynamin_M PF01031.15 KND95718.1 - 2.6e-104 348.1 0.4 2.6e-104 348.1 0.3 2.0 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KND95718.1 - 2.5e-56 190.1 0.0 5.2e-56 189.0 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KND95718.1 - 3.1e-28 97.5 3.4 1.2e-27 95.6 2.4 2.1 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KND95718.1 - 0.00098 19.0 0.4 0.0094 15.9 0.3 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KND95718.1 - 0.059 13.8 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Macro PF01661.16 KND95719.1 - 6.1e-27 93.8 0.0 7.2e-27 93.6 0.0 1.1 1 0 0 1 1 1 1 Macro domain EGF_3 PF12947.2 KND95721.1 - 0.028 14.4 0.5 0.053 13.4 0.4 1.4 1 0 0 1 1 1 0 EGF domain DUF4252 PF14060.1 KND95721.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) TruB_N PF01509.13 KND95723.1 - 3.8e-40 137.4 0.1 1.2e-39 135.9 0.1 1.9 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) Erf4 PF10256.4 KND95724.1 - 2.2e-24 85.6 0.0 3.1e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family PPR_2 PF13041.1 KND95726.1 - 4.3e-18 65.0 4.7 8.4e-06 25.6 0.1 5.3 5 0 0 5 5 5 3 PPR repeat family PPR_3 PF13812.1 KND95726.1 - 3.4e-14 51.8 1.2 0.061 13.6 0.0 8.3 8 0 0 8 8 8 4 Pentatricopeptide repeat domain PPR PF01535.15 KND95726.1 - 4e-08 32.7 11.0 0.015 15.2 0.2 6.9 8 0 0 8 8 8 3 PPR repeat Cyto_heme_lyase PF01265.12 KND95728.1 - 2.8e-69 233.5 0.0 3.8e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase OTU PF02338.14 KND95732.1 - 3.2e-16 60.0 1.6 9.2e-16 58.5 0.0 2.3 3 0 0 3 3 3 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KND95732.1 - 1.5e-05 24.5 1.8 0.00049 19.5 0.0 2.6 2 1 1 3 3 3 1 Peptidase C65 Otubain COX4 PF02936.9 KND95732.1 - 0.022 14.4 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV T2SM PF04612.7 KND95732.1 - 0.05 13.4 0.9 0.16 11.7 0.5 1.9 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M Big_2 PF02368.13 KND95732.1 - 0.11 12.4 0.0 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) DUF603 PF04645.7 KND95732.1 - 1.5 8.6 5.8 0.58 10.0 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF603 Cyclin_N PF00134.18 KND95734.1 - 3.8e-37 126.6 0.4 7.7e-37 125.6 0.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cupin_8 PF13621.1 KND95735.1 - 1.9e-50 171.7 0.0 4.8e-48 163.8 0.0 2.3 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KND95735.1 - 2.6e-08 33.5 0.0 3.3e-06 26.5 0.0 2.5 2 0 0 2 2 2 2 Cupin superfamily protein DUF3650 PF12368.3 KND95735.1 - 0.021 14.3 0.6 30 4.2 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3650) BNIP2 PF12496.3 KND95737.1 - 0.054 13.6 0.2 0.15 12.2 0.1 1.8 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 ETF_QO PF05187.8 KND95738.1 - 6.1e-39 132.4 0.0 1.2e-38 131.4 0.0 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 KND95738.1 - 6.3e-09 35.2 0.3 0.00076 18.4 0.1 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KND95738.1 - 1.4e-08 34.0 0.2 0.00039 19.4 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KND95738.1 - 3.6e-06 26.9 0.1 1.7e-05 24.7 0.0 2.2 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KND95738.1 - 4.2e-06 26.0 0.0 0.0023 17.0 0.0 2.2 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 KND95738.1 - 0.0004 18.9 0.2 0.0032 15.9 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 KND95738.1 - 0.00045 20.3 0.0 0.00083 19.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KND95738.1 - 0.0026 16.8 0.0 0.0037 16.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KND95738.1 - 0.0045 16.8 0.0 0.0071 16.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 KND95738.1 - 0.0099 16.2 0.7 0.029 14.7 0.5 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Lycopene_cycl PF05834.7 KND95738.1 - 0.03 13.2 0.1 0.044 12.6 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein K_oxygenase PF13434.1 KND95738.1 - 0.034 13.0 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 KND95738.1 - 0.037 13.1 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KND95738.1 - 0.052 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Fer4_10 PF13237.1 KND95738.1 - 0.1 12.3 0.7 0.21 11.3 0.5 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain FAD_binding_8 PF08022.7 KND95739.1 - 1.4e-21 76.2 0.0 3.6e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KND95739.1 - 2e-21 76.5 0.0 3.9e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KND95739.1 - 2.1e-18 66.6 14.6 2.1e-18 66.6 10.1 2.3 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 KND95739.1 - 0.069 13.7 0.0 0.39 11.2 0.0 2.4 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain RhoGEF PF00621.15 KND95741.1 - 8e-36 123.5 0.8 8e-36 123.5 0.6 1.7 2 0 0 2 2 2 1 RhoGEF domain PH_10 PF15411.1 KND95741.1 - 2.3e-16 60.0 0.7 1.2e-15 57.6 0.5 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 KND95741.1 - 3e-16 59.2 0.1 7.8e-16 57.9 0.0 1.8 2 0 0 2 2 2 1 CDC24 Calponin PB1 PF00564.19 KND95741.1 - 1.3e-07 31.1 2.3 4.1e-07 29.5 0.2 2.6 3 0 0 3 3 3 1 PB1 domain CH PF00307.26 KND95741.1 - 0.086 12.8 1.3 0.2 11.6 0.0 2.3 3 0 0 3 3 3 0 Calponin homology (CH) domain SpoIISA_toxin PF14171.1 KND95743.1 - 0.0031 16.8 0.7 0.0046 16.2 0.5 1.3 1 1 0 1 1 1 1 Toxin SpoIISA, type II toxin-antitoxin system SecE PF00584.15 KND95745.1 - 0.0022 17.5 0.1 0.0022 17.5 0.1 3.0 2 0 0 2 2 2 1 SecE/Sec61-gamma subunits of protein translocation complex Cortexin PF11057.3 KND95745.1 - 0.016 14.7 1.9 0.071 12.7 0.6 2.5 2 0 0 2 2 2 0 Cortexin of kidney Prion_bPrPp PF11587.3 KND95745.1 - 0.47 10.1 2.5 2 8.1 1.7 2.1 1 0 0 1 1 1 0 Major prion protein bPrPp - N terminal Zn_clus PF00172.13 KND95746.1 - 2.9e-08 33.4 14.5 5.8e-08 32.5 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF972 PF06156.8 KND95746.1 - 0.032 14.5 10.4 0.035 14.4 1.3 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Bac_Ubq_Cox PF01654.12 KND95746.1 - 0.088 11.2 0.0 0.14 10.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial Cytochrome Ubiquinol Oxidase PAT1 PF09770.4 KND95746.1 - 2.4 6.3 44.2 5.3 5.1 30.6 1.6 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rad9 PF04139.8 KND95748.1 - 1.4e-15 57.1 0.6 2.8e-15 56.1 0.4 1.5 1 1 0 1 1 1 1 Rad9 Rad1 PF02144.11 KND95748.1 - 0.042 12.6 0.2 0.49 9.1 0.1 2.4 2 1 1 3 3 3 0 Repair protein Rad1/Rec1/Rad17 Asp_Glu_race PF01177.17 KND95749.1 - 9.8e-29 100.8 0.0 1.1e-28 100.6 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase TLD PF07534.11 KND95750.1 - 4.4e-26 91.5 0.6 7.8e-23 81.0 0.0 2.1 2 0 0 2 2 2 2 TLD MTHFR PF02219.12 KND95751.1 - 2e-117 391.3 0.0 3.5e-117 390.5 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase UDP-g_GGTase PF06427.6 KND95752.1 - 1.6e-27 96.2 0.9 2.9e-26 92.1 0.1 2.5 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 KND95752.1 - 3.1e-09 36.5 2.2 8.8e-09 35.0 1.5 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 8 DUF1074 PF06382.6 KND95753.1 - 0.00067 19.6 1.1 0.00067 19.6 0.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1074) HMG_box PF00505.14 KND95753.1 - 0.06 13.6 0.7 0.19 12.0 0.5 2.0 1 0 0 1 1 1 0 HMG (high mobility group) box HMG_box_2 PF09011.5 KND95753.1 - 0.097 13.0 0.6 0.097 13.0 0.4 2.2 2 0 0 2 2 2 0 HMG-box domain AAR2 PF05282.6 KND95754.1 - 1.2e-50 172.4 0.9 1.8e-50 171.8 0.6 1.2 1 0 0 1 1 1 1 AAR2 protein Voltage_CLC PF00654.15 KND95755.1 - 2.7e-79 266.7 17.8 3.8e-79 266.2 12.4 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 KND95755.1 - 0.00039 20.1 1.5 0.044 13.5 0.1 3.1 3 0 0 3 3 3 2 CBS domain WD40 PF00400.27 KND95756.1 - 2.1e-33 112.9 2.2 2.1e-06 27.4 0.0 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KND95756.1 - 0.0019 17.0 0.1 0.033 12.9 0.0 2.2 2 0 0 2 2 2 1 Nup133 N terminal like eIF2A PF08662.6 KND95756.1 - 0.0048 16.6 0.0 0.036 13.7 0.0 2.3 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 KND95758.1 - 0.00016 21.3 0.0 0.00028 20.5 0.0 1.4 1 0 0 1 1 1 1 LisH PP1_bind PF15276.1 KND95758.1 - 0.079 12.9 0.1 0.079 12.9 0.1 4.6 4 1 0 4 4 4 0 Protein phosphatase 1 binding V_ATPase_I PF01496.14 KND95758.1 - 7.9 4.1 11.4 21 2.8 7.9 1.6 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ALG3 PF05208.8 KND95759.1 - 1.3e-100 337.2 25.3 1.6e-100 336.9 17.5 1.1 1 0 0 1 1 1 1 ALG3 protein RRM_5 PF13893.1 KND95760.1 - 0.00057 19.6 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TORC_N PF12884.2 KND95760.1 - 0.57 10.7 5.3 1.9 9.0 3.7 1.9 1 0 0 1 1 1 0 Transducer of regulated CREB activity, N terminus Clc-like PF07062.7 KND95761.1 - 0.041 13.1 0.0 0.042 13.0 0.0 1.1 1 0 0 1 1 1 0 Clc-like Asp PF00026.18 KND95762.1 - 1.2e-65 221.8 1.5 2.1e-65 221.0 1.0 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KND95762.1 - 3.2e-05 23.9 0.0 0.00024 21.0 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KND95762.1 - 3.4e-05 24.2 0.1 1.6 9.2 0.0 3.9 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.1 KND95762.1 - 0.028 14.2 0.1 12 5.8 0.0 3.3 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease PEX11 PF05648.9 KND95763.1 - 7.9e-47 159.3 0.9 8.8e-47 159.2 0.7 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) ATPase_gene1 PF09527.5 KND95763.1 - 0.47 10.2 3.8 0.91 9.3 2.6 1.6 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit (ATPase_gene1) Spc7 PF08317.6 KND95764.1 - 1.2e-68 231.1 15.5 1.2e-68 231.1 10.8 2.0 3 0 0 3 3 3 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 KND95764.1 - 1.8e-07 30.7 2.8 8.4e-06 25.3 0.1 3.5 4 0 0 4 4 4 2 Spc7_C2 TPR_11 PF13414.1 KND95766.1 - 6.9e-30 102.4 40.4 4e-07 29.5 0.1 11.9 7 3 7 14 14 14 8 TPR repeat TPR_1 PF00515.23 KND95766.1 - 1.7e-19 68.5 18.5 0.0045 16.5 0.0 14.2 15 1 0 15 15 15 3 Tetratricopeptide repeat TPR_2 PF07719.12 KND95766.1 - 2.9e-19 67.3 29.0 0.00015 21.4 0.1 14.5 16 1 0 16 16 15 4 Tetratricopeptide repeat TPR_19 PF14559.1 KND95766.1 - 2.2e-18 66.3 29.3 8e-06 26.1 0.5 10.4 9 2 2 11 11 10 5 Tetratricopeptide repeat TPR_12 PF13424.1 KND95766.1 - 1.7e-17 63.1 29.9 0.0038 17.1 0.0 11.4 10 3 4 14 14 12 6 Tetratricopeptide repeat TPR_6 PF13174.1 KND95766.1 - 2e-16 59.2 15.7 0.032 14.6 0.0 11.9 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_14 PF13428.1 KND95766.1 - 3.1e-16 58.4 20.0 0.015 15.8 0.2 13.6 10 4 6 16 16 14 4 Tetratricopeptide repeat TPR_8 PF13181.1 KND95766.1 - 2.3e-14 51.9 37.7 0.0037 16.9 0.0 13.2 14 1 1 15 15 15 5 Tetratricopeptide repeat Apc3 PF12895.2 KND95766.1 - 2.7e-13 49.8 22.9 0.0045 17.0 0.1 8.6 5 2 4 9 9 9 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KND95766.1 - 3e-11 43.6 29.9 3.1e-06 27.7 0.1 10.1 9 2 2 12 12 11 3 Tetratricopeptide repeat TPR_9 PF13371.1 KND95766.1 - 6.3e-09 35.5 6.6 0.0087 15.8 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 KND95766.1 - 1.5e-06 27.5 20.3 0.22 11.4 0.0 10.6 13 1 1 14 14 14 1 Tetratricopeptide repeat TPR_17 PF13431.1 KND95766.1 - 2.4e-06 27.3 15.8 15 6.1 0.0 11.9 13 0 0 13 13 13 0 Tetratricopeptide repeat Sld5 PF05916.6 KND95767.1 - 2.7e-16 59.7 0.5 3.6e-16 59.4 0.4 1.2 1 0 0 1 1 1 1 GINS complex protein TPR_17 PF13431.1 KND95767.1 - 0.1 12.8 0.1 0.39 11.0 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_PK PF05891.7 KND95769.1 - 5e-79 264.6 0.0 5.7e-79 264.4 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase ThiF PF00899.16 KND95770.1 - 2e-38 131.2 0.2 3.5e-38 130.5 0.1 1.4 1 0 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 KND95770.1 - 0.0016 17.5 1.1 0.0077 15.2 0.8 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KND95770.1 - 0.0016 18.5 0.1 0.0033 17.5 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KND95770.1 - 0.017 15.1 0.9 0.14 12.1 0.0 2.5 3 0 0 3 3 3 0 TrkA-N domain NAD_binding_7 PF13241.1 KND95770.1 - 0.063 13.5 0.2 0.3 11.3 0.1 2.2 2 1 0 2 2 2 0 Putative NAD(P)-binding ApbA PF02558.11 KND95770.1 - 0.089 12.2 0.2 0.22 10.9 0.1 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DUF1279 PF06916.8 KND95771.1 - 1.4e-26 92.6 0.0 2.2e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Mito_carr PF00153.22 KND95772.1 - 9e-59 195.2 0.0 5.4e-20 70.9 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Abhydrolase_6 PF12697.2 KND95773.1 - 6.2e-39 134.2 0.0 7.1e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND95773.1 - 5.7e-31 107.8 0.0 6.8e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KND95773.1 - 6e-24 84.4 0.0 5.3e-22 78.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KND95773.1 - 1.5e-12 47.1 0.6 4.8e-12 45.5 0.1 2.0 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 KND95773.1 - 1.8e-07 30.6 0.1 0.0011 18.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KND95773.1 - 5.3e-05 22.7 0.0 9.2e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DUF915 PF06028.6 KND95773.1 - 0.00036 19.6 0.0 0.0098 14.9 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF1749 PF08538.5 KND95773.1 - 0.00085 18.3 0.0 0.16 10.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1749) Abhydrolase_4 PF08386.5 KND95773.1 - 0.014 15.2 0.0 0.042 13.7 0.0 1.8 2 0 0 2 2 1 0 TAP-like protein AXE1 PF05448.7 KND95773.1 - 0.021 13.3 0.0 1.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DLH PF01738.13 KND95773.1 - 0.028 13.6 0.1 0.22 10.7 0.0 2.1 2 1 0 2 2 2 0 Dienelactone hydrolase family Ser_hydrolase PF06821.8 KND95773.1 - 0.047 13.2 0.0 1.8 8.1 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase Ndr PF03096.9 KND95773.1 - 0.057 11.8 0.0 0.066 11.6 0.0 1.2 1 0 0 1 1 1 0 Ndr family FSH1 PF03959.8 KND95773.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) NDT80_PhoG PF05224.7 KND95775.1 - 7.6e-55 185.8 0.1 1.4e-54 184.8 0.0 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family RhoGAP PF00620.22 KND95779.1 - 1.5e-34 118.8 3.1 1.3e-20 73.5 0.0 2.7 3 0 0 3 3 3 2 RhoGAP domain Leo1 PF04004.8 KND95780.1 - 3.6e-40 137.4 0.5 3.6e-40 137.4 0.4 2.2 3 0 0 3 3 3 1 Leo1-like protein ADK PF00406.17 KND95781.1 - 2.6e-43 147.4 0.0 3.3e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KND95781.1 - 4.8e-11 42.1 0.0 8.1e-11 41.3 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 KND95781.1 - 3.6e-05 24.0 0.1 0.0001 22.6 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 KND95781.1 - 5.4e-05 23.9 0.1 0.00011 23.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KND95781.1 - 0.00035 20.4 0.4 0.0012 18.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain HlyC PF02794.11 KND95781.1 - 0.014 15.0 0.2 0.029 13.9 0.0 1.6 2 0 0 2 2 2 0 RTX toxin acyltransferase family Mg_chelatase PF01078.16 KND95781.1 - 0.029 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ADK PF00406.17 KND95783.1 - 1.9e-31 109.0 0.0 2.2e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KND95783.1 - 1.2e-13 50.4 0.0 2.2e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 KND95783.1 - 8.6e-05 23.3 0.3 0.0004 21.1 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND95783.1 - 0.00061 19.5 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KND95783.1 - 0.00065 19.5 0.1 0.0045 16.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KND95783.1 - 0.0038 16.3 0.0 0.0071 15.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KND95783.1 - 0.014 15.7 0.8 0.033 14.4 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KND95783.1 - 0.037 14.1 0.1 0.086 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KND95783.1 - 0.043 13.7 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 KND95783.1 - 0.094 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.13 KND95783.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA PF00004.24 KND95783.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KND95783.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF1227 PF06777.6 KND95784.1 - 3.4e-62 208.4 0.8 7.7e-62 207.3 0.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 KND95784.1 - 6.4e-51 172.2 0.6 1.4e-50 171.0 0.4 1.6 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 KND95784.1 - 6.9e-44 149.7 0.0 2.3e-43 148.0 0.0 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.24 KND95784.1 - 0.00047 19.6 0.0 0.12 11.8 0.0 2.8 2 0 0 2 2 2 2 DEAD/DEAH box helicase SNF2_N PF00176.18 KND95784.1 - 0.003 16.3 0.2 0.47 9.1 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.10 KND95784.1 - 0.01 15.6 1.6 1.3 8.8 0.0 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Actin PF00022.14 KND95785.1 - 2.7e-07 29.3 0.0 0.00042 18.8 0.0 2.7 1 1 2 3 3 3 2 Actin Metallophos_2 PF12850.2 KND95785.1 - 0.081 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain BAR PF03114.13 KND95787.1 - 3.4e-52 177.2 2.9 3.9e-52 177.0 2.0 1.0 1 0 0 1 1 1 1 BAR domain Cast PF10174.4 KND95787.1 - 0.015 13.3 0.3 0.019 13.0 0.2 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF4164 PF13747.1 KND95787.1 - 0.63 10.2 6.0 0.25 11.5 0.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) AAA PF00004.24 KND95791.1 - 2.5e-40 137.7 0.0 4.4e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KND95791.1 - 5.4e-06 26.5 0.0 0.00089 19.4 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 KND95791.1 - 2.1e-05 24.2 0.0 0.00011 21.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KND95791.1 - 0.00014 21.9 0.0 0.00041 20.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 KND95791.1 - 0.0003 20.7 0.0 0.00064 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KND95791.1 - 0.001 18.0 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KND95791.1 - 0.0014 19.4 0.1 0.0031 18.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KND95791.1 - 0.0053 15.8 0.0 0.0091 15.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KND95791.1 - 0.0058 16.3 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 KND95791.1 - 0.0089 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KND95791.1 - 0.012 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 KND95791.1 - 0.014 15.5 0.0 0.068 13.3 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 KND95791.1 - 0.019 14.8 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KND95791.1 - 0.019 14.1 0.0 0.09 11.9 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KND95791.1 - 0.02 14.5 0.0 0.063 12.8 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KND95791.1 - 0.023 14.9 0.0 0.058 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KND95791.1 - 0.023 14.5 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KND95791.1 - 0.024 14.3 0.0 4.5 6.9 0.0 2.4 1 1 1 2 2 2 0 Archaeal ATPase IstB_IS21 PF01695.12 KND95791.1 - 0.029 13.7 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 KND95791.1 - 0.032 14.2 0.0 0.083 12.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.8 KND95791.1 - 0.035 12.8 0.0 0.065 11.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_24 PF13479.1 KND95791.1 - 0.07 12.7 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KND95791.1 - 0.13 11.7 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_pol_Rbc25 PF08292.7 KND95792.1 - 5.4e-44 149.2 0.1 7.2e-44 148.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 KND95792.1 - 2.2e-14 53.3 0.0 3.6e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 KND95792.1 - 0.083 12.9 0.0 0.19 11.8 0.0 1.8 1 1 0 1 1 1 0 S1 RNA binding domain RRM_1 PF00076.17 KND95793.1 - 1.6e-19 69.3 0.1 2.1e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND95793.1 - 7.5e-12 45.0 0.0 9.8e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND95793.1 - 0.015 15.1 0.1 0.021 14.6 0.1 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Matrilin_ccoil PF10393.4 KND95795.1 - 0.027 13.8 0.0 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin HLH PF00010.21 KND95796.1 - 7e-13 48.0 0.7 1.6e-12 46.9 0.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RTC4 PF14474.1 KND95799.1 - 3.2e-23 82.0 1.3 3.5e-23 81.8 0.0 1.7 2 0 0 2 2 2 1 RTC4-like domain Pterin_bind PF00809.17 KND95800.1 - 3.4e-54 183.3 0.0 3.2e-39 134.5 0.0 2.7 2 0 0 2 2 2 2 Pterin binding enzyme HPPK PF01288.15 KND95800.1 - 7.1e-37 125.9 0.0 1.5e-36 124.9 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 KND95800.1 - 5.8e-30 103.7 0.0 1.3e-16 60.7 0.1 2.8 3 0 0 3 3 3 2 Dihydroneopterin aldolase RRM_1 PF00076.17 KND95801.1 - 1.1e-12 47.3 0.1 2.6e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND95801.1 - 9.8e-12 44.5 0.1 1.7e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND95801.1 - 8.4e-11 41.6 0.0 1.5e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.16 KND95801.1 - 2.6e-06 27.7 0.0 4.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4357 PF14267.1 KND95801.1 - 0.1 12.1 0.2 0.3 10.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) adh_short PF00106.20 KND95802.1 - 3.9e-28 98.4 0.8 4.8e-28 98.1 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND95802.1 - 2.1e-26 93.1 0.0 2.5e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND95802.1 - 5.8e-13 48.8 0.4 8.5e-13 48.3 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KND95802.1 - 7.1e-06 25.6 0.7 2.1e-05 24.0 0.5 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KND95802.1 - 1.6e-05 23.8 0.5 2.1e-05 23.3 0.3 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 KND95802.1 - 0.0057 17.0 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 KND95802.1 - 0.015 14.2 0.0 0.023 13.5 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain 3HCDH_N PF02737.13 KND95802.1 - 0.016 14.8 0.1 0.024 14.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KND95802.1 - 0.017 14.0 0.1 0.025 13.5 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DFP PF04127.10 KND95802.1 - 0.062 12.9 0.2 0.11 12.0 0.2 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Ldh_1_N PF00056.18 KND95802.1 - 0.1 12.3 0.2 0.19 11.5 0.2 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_63 PF03200.11 KND95803.1 - 1.4e-07 29.8 2.9 2.5e-05 22.3 0.2 3.2 2 1 0 2 2 2 2 Mannosyl oligosaccharide glucosidase DUF269 PF03270.8 KND95803.1 - 0.18 11.8 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF269 V-SNARE PF05008.10 KND95804.1 - 7.2e-19 67.7 6.1 7.2e-19 67.7 4.2 2.5 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 KND95804.1 - 1.5e-17 63.3 4.4 1.5e-17 63.3 3.0 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF3987 PF13148.1 KND95804.1 - 0.003 16.1 4.2 0.003 16.1 2.9 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3987) Sec20 PF03908.8 KND95804.1 - 0.014 15.0 1.9 0.016 14.8 0.4 1.8 1 1 0 1 1 1 0 Sec20 DUF106 PF01956.11 KND95804.1 - 0.046 13.2 0.0 0.17 11.4 0.0 2.0 1 1 0 1 1 1 0 Integral membrane protein DUF106 DUF885 PF05960.6 KND95804.1 - 0.052 12.6 2.6 0.055 12.6 1.8 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) YqjK PF13997.1 KND95804.1 - 0.053 13.6 0.1 0.053 13.6 0.1 2.9 4 0 0 4 4 4 0 YqjK-like protein DUF2803 PF10972.3 KND95804.1 - 0.12 11.8 4.2 0.19 11.2 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2803) MRP-S26 PF14943.1 KND95804.1 - 1 8.8 9.9 1.4 8.4 6.6 1.4 1 1 0 1 1 1 0 Mitochondrial ribosome subunit S26 Fer2 PF00111.22 KND95805.1 - 1.3e-14 53.6 0.4 1.7e-14 53.2 0.2 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Filament PF00038.16 KND95808.1 - 0.1 12.0 45.8 0.55 9.6 31.0 2.4 1 1 0 1 1 1 0 Intermediate filament protein Reo_sigmaC PF04582.7 KND95808.1 - 0.17 10.9 5.0 1.5 7.9 1.2 2.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 KND95808.1 - 1.5 8.6 53.1 0.92 9.3 2.4 5.2 1 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HrpB7 PF09486.5 KND95808.1 - 3.5 7.5 21.1 0.67 9.8 5.5 3.6 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) SAGA-Tad1 PF12767.2 KND95809.1 - 2.8e-61 207.3 3.7 5.4e-61 206.4 2.5 1.4 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.9 KND95809.1 - 0.0004 19.7 0.0 0.00069 18.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family MFS_1 PF07690.11 KND95811.1 - 1.3e-35 122.8 59.8 1.8e-33 115.7 41.8 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily ATP-synt_J PF04911.7 KND95819.1 - 8e-08 31.6 0.1 8.3e-08 31.5 0.1 1.0 1 0 0 1 1 1 1 ATP synthase j chain Methyltransf_16 PF10294.4 KND95821.1 - 1.6e-17 63.4 0.0 2.5e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KND95821.1 - 1.3e-05 25.6 0.0 2.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND95821.1 - 0.00023 20.7 0.0 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND95821.1 - 0.013 15.4 0.0 0.047 13.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 KND95821.1 - 0.019 14.7 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KND95821.1 - 0.057 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 KND95821.1 - 0.12 12.9 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Allantoicase PF03561.10 KND95822.1 - 5.6e-92 305.1 0.0 8.8e-49 164.8 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat KA1 PF02149.14 KND95823.1 - 0.13 11.6 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinase associated domain 1 Flagellin_N PF00669.15 KND95825.1 - 0.54 10.0 6.6 0.14 11.9 0.7 2.8 3 0 0 3 3 3 0 Bacterial flagellin N-terminal helical region Fzo_mitofusin PF04799.8 KND95825.1 - 0.74 9.1 8.7 0.1 11.9 1.8 2.4 1 1 1 2 2 2 0 fzo-like conserved region Baculo_PEP_C PF04513.7 KND95825.1 - 2 8.2 6.7 0.32 10.8 0.2 2.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_lysis PF03245.8 KND95825.1 - 3.5 7.6 15.0 2.5 8.1 1.5 3.5 2 1 1 3 3 3 0 Bacteriophage Rz lysis protein HTH_Tnp_Tc5 PF03221.11 KND95830.1 - 5.4e-12 45.3 0.1 1.1e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Anoctamin PF04547.7 KND95830.1 - 5 5.6 5.4 0.41 9.2 0.4 1.5 2 0 0 2 2 2 0 Calcium-activated chloride channel TEX13 PF15186.1 KND95831.1 - 0.083 12.4 0.0 0.096 12.2 0.0 1.0 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family tRNA_m1G_MT PF01746.16 KND95832.1 - 1.3e-34 119.4 0.0 1.3e-34 119.4 0.0 1.6 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase Toxin_56 PF15534.1 KND95832.1 - 0.99 9.9 4.1 2.7 8.5 2.9 1.7 1 0 0 1 1 1 0 Putative toxin 56 NARP1 PF12569.3 KND95832.1 - 7.2 5.2 7.5 5.8 5.5 4.1 1.6 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Fungal_trans PF04082.13 KND95833.1 - 1.9e-09 36.8 1.6 4.2e-09 35.6 0.0 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND95833.1 - 7.9e-09 35.2 12.7 1.6e-08 34.3 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PQ-loop PF04193.9 KND95834.1 - 1.6e-40 136.4 18.2 4.1e-22 77.4 1.2 2.9 3 0 0 3 3 3 2 PQ loop repeat DUF3784 PF12650.2 KND95834.1 - 7.2 6.6 14.5 1.4 8.9 0.4 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF3784) AMP-binding PF00501.23 KND95835.1 - 1.7e-60 204.6 0.0 4.2e-60 203.2 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme tRNA_int_end_N2 PF12928.2 KND95837.1 - 1.7e-19 69.0 0.0 2.9e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 KND95837.1 - 0.07 12.6 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Smg4_UPF3 PF03467.10 KND95839.1 - 3.7e-11 43.3 0.0 3.7e-11 43.3 0.0 2.9 1 1 2 3 3 3 1 Smg-4/UPF3 family PCI PF01399.22 KND95840.1 - 0.00016 21.9 1.2 0.0008 19.6 0.0 2.7 3 1 1 4 4 4 1 PCI domain F-box-like_2 PF13013.1 KND95841.1 - 0.0076 15.9 0.1 0.027 14.1 0.1 2.0 1 0 0 1 1 1 1 F-box-like domain Ferric_reduct PF01794.14 KND95843.1 - 1.1e-12 48.1 11.3 1.4e-12 47.7 7.0 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KND95843.1 - 0.0011 18.9 0.0 0.058 13.2 0.0 2.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain zf-CCHC PF00098.18 KND95845.1 - 0.0019 18.0 45.1 0.0025 17.6 1.1 5.2 5 1 0 5 5 5 4 Zinc knuckle zf-CCHC_3 PF13917.1 KND95845.1 - 0.023 14.3 1.0 0.023 14.3 0.7 5.5 3 1 3 6 6 6 0 Zinc knuckle Cg6151-P PF10233.4 KND95846.1 - 3.6e-42 142.8 13.7 4.8e-42 142.5 9.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P YwiC PF14256.1 KND95846.1 - 0.022 14.8 5.0 0.099 12.7 0.4 2.1 2 0 0 2 2 2 0 YwiC-like protein DUF2238 PF09997.4 KND95846.1 - 0.41 10.0 4.0 0.31 10.4 0.2 2.3 2 1 1 3 3 3 0 Predicted membrane protein (DUF2238) Clc-like PF07062.7 KND95846.1 - 0.61 9.2 8.2 1 8.5 5.7 1.4 1 1 0 1 1 1 0 Clc-like Sigma_reg_N PF13800.1 KND95846.1 - 5 7.2 7.5 0.52 10.3 0.1 2.2 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Shisa PF13908.1 KND95846.1 - 9 6.4 6.1 12 6.0 0.0 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator MMR_HSR1_C PF08438.5 KND95847.1 - 1.5e-31 108.8 0.0 2.5e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 KND95847.1 - 3.2e-18 65.7 0.0 1e-17 64.1 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KND95847.1 - 1.7e-08 33.9 0.6 1.4e-06 27.7 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KND95847.1 - 0.00074 19.0 2.6 0.21 10.9 0.0 2.9 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 KND95847.1 - 0.0021 16.8 0.5 0.0067 15.2 0.1 2.0 2 0 0 2 2 2 1 ArgK protein AAA_17 PF13207.1 KND95847.1 - 0.0034 18.1 0.2 0.065 14.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 KND95847.1 - 0.004 16.7 0.2 1 8.8 0.0 2.6 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 KND95847.1 - 0.0048 17.1 0.1 0.1 12.8 0.1 2.3 2 0 0 2 2 2 1 ABC transporter Dynamin_N PF00350.18 KND95847.1 - 0.013 15.3 0.1 0.035 13.9 0.0 1.7 2 0 0 2 2 2 0 Dynamin family AAA_10 PF12846.2 KND95847.1 - 0.048 13.0 0.1 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 KND95847.1 - 0.056 13.7 0.3 0.65 10.3 0.0 2.6 2 1 1 3 3 3 0 AAA domain AAA_14 PF13173.1 KND95847.1 - 0.078 12.8 0.0 9.9 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KND95847.1 - 0.089 12.7 0.2 0.22 11.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.1 KND95847.1 - 0.2 11.1 0.4 0.57 9.7 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KND95847.1 - 0.31 10.6 1.9 0.44 10.0 0.5 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain CRAL_TRIO PF00650.15 KND95848.1 - 1.3e-19 70.1 0.0 2.1e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KND95848.1 - 4.4e-10 39.5 3.1 3.5e-09 36.6 0.1 3.2 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain DUF3877 PF12993.2 KND95848.1 - 0.043 13.3 0.3 0.076 12.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) Peptidase_C12 PF01088.16 KND95848.1 - 0.045 12.9 0.1 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 Prok_Ub PF14454.1 KND95848.1 - 0.094 12.3 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic Ubiquitin DUF2762 PF10960.3 KND95848.1 - 0.61 9.8 4.1 0.26 11.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) DnaJ PF00226.26 KND95849.1 - 4.8e-23 80.6 1.3 1.2e-22 79.3 0.9 1.7 1 0 0 1 1 1 1 DnaJ domain GBP_C PF02841.9 KND95849.1 - 0.012 14.8 16.4 0.02 14.0 11.4 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain MRP-S26 PF14943.1 KND95849.1 - 0.092 12.3 23.4 1.2 8.6 15.8 2.5 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Spore_III_AF PF09581.5 KND95849.1 - 6.4 6.5 10.8 13 5.5 7.5 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) VIT1 PF01988.14 KND95849.1 - 8.9 5.7 6.8 16 4.8 4.7 1.5 1 0 0 1 1 1 0 VIT family PigN PF04987.9 KND95850.1 - 1.6e-133 445.5 43.5 2.6e-133 444.9 30.2 1.3 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 KND95850.1 - 1.4e-11 44.4 0.1 8.8e-10 38.4 0.0 2.3 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KND95850.1 - 3.6e-07 29.6 0.1 5.8e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 KND95850.1 - 1.5e-05 24.5 0.0 2.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily IGPS PF00218.16 KND95851.1 - 1.1e-72 244.1 0.0 1.6e-72 243.6 0.0 1.2 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 KND95851.1 - 5.3e-48 163.0 0.1 8.4e-48 162.3 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KND95851.1 - 7.3e-08 32.1 0.1 1.7e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 Rep_fac-A_3 PF08661.6 KND95852.1 - 2e-18 66.2 0.0 2.3e-18 66.0 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Ten1_2 PF15490.1 KND95852.1 - 0.0015 18.0 0.0 0.0029 17.1 0.0 1.6 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit tRNA_anti-codon PF01336.20 KND95852.1 - 0.021 14.6 0.5 0.32 10.8 0.3 2.1 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.2 KND95852.1 - 0.23 10.9 0.9 1.2 8.6 0.1 1.9 1 1 1 2 2 2 0 tRNA_anti-like PFU PF09070.6 KND95853.1 - 4.5e-44 149.1 0.0 1.7e-43 147.3 0.0 2.0 2 0 0 2 2 2 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 KND95853.1 - 4.3e-41 137.3 19.8 2.9e-08 33.3 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat PUL PF08324.6 KND95853.1 - 9e-37 126.3 7.1 9e-37 126.3 4.9 1.6 2 0 0 2 2 2 1 PUL domain EF-hand_8 PF13833.1 KND95853.1 - 0.048 13.2 0.6 0.13 11.9 0.4 1.7 1 0 0 1 1 1 0 EF-hand domain pair Chorion_S16 PF05836.7 KND95853.1 - 0.093 12.6 0.0 0.55 10.1 0.0 2.1 1 1 1 2 2 2 0 Chorion protein S16 Syja_N PF02383.13 KND95855.1 - 4.4e-89 298.3 2.1 5.9e-89 297.9 1.5 1.2 1 0 0 1 1 1 1 SacI homology domain FoP_duplication PF13865.1 KND95857.1 - 1.3e-08 35.1 4.7 2.6e-08 34.1 3.1 1.6 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_6 PF14259.1 KND95857.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 KND95858.1 - 1.3e-33 116.1 13.9 1.3e-33 116.1 9.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Ribonucleas_3_3 PF14622.1 KND95859.1 - 0.00011 22.2 0.5 0.00018 21.4 0.3 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 KND95859.1 - 0.00015 22.2 0.0 0.00034 21.1 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 KND95859.1 - 0.02 15.3 0.6 0.05 14.0 0.2 2.0 2 0 0 2 2 2 0 Ribonuclease III domain Mito_carr PF00153.22 KND95860.1 - 1.7e-45 152.6 8.0 8.9e-19 67.0 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1761 PF08570.5 KND95860.1 - 0.056 13.4 0.4 0.16 12.0 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1761) Exotox-A_bind PF09101.5 KND95861.1 - 0.086 11.9 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Exotoxin A binding Rhamnogal_lyase PF06045.6 KND95861.1 - 0.1 11.8 0.1 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Rhamnogalacturonate lyase family DUF3407 PF11887.3 KND95862.1 - 0.044 13.0 0.0 0.067 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3407) RNA_polI_A34 PF08208.6 KND95864.1 - 3.7e-45 154.0 25.7 5.2e-45 153.5 17.8 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.7 KND95864.1 - 0.0099 15.8 10.5 0.011 15.7 7.3 1.2 1 0 0 1 1 1 1 GAGA binding protein-like family Vfa1 PF08432.5 KND95864.1 - 0.15 12.0 25.0 0.24 11.4 17.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.12 KND95864.1 - 0.81 9.4 7.7 1 9.1 5.3 1.2 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 KND95864.1 - 0.97 9.2 14.3 1.2 8.9 9.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNase_H2-Ydr279 PF09468.5 KND95864.1 - 5.1 6.2 20.9 6.5 5.8 14.5 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF1510 PF07423.6 KND95864.1 - 9.6 5.5 25.2 15 4.8 17.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ribosomal_S20p PF01649.13 KND95866.1 - 0.58 10.5 7.9 0.63 10.4 1.3 2.4 2 0 0 2 2 2 0 Ribosomal protein S20 Methyltransf_6 PF03737.10 KND95867.1 - 2.2e-23 82.8 0.1 3.1e-23 82.3 0.1 1.2 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase Pkinase PF00069.20 KND95869.1 - 1.1e-68 231.2 0.0 1.4e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND95869.1 - 1.7e-39 135.4 0.0 2.3e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND95869.1 - 1.3e-05 24.3 0.0 2.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KND95869.1 - 0.1 11.6 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KND95870.1 - 4.5e-37 127.6 0.0 1e-36 126.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND95870.1 - 5.3e-13 48.6 0.1 2e-12 46.7 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase RNA_pol_3_Rpc31 PF11705.3 KND95870.1 - 0.023 14.6 2.2 0.023 14.6 1.5 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Kdo PF06293.9 KND95870.1 - 0.029 13.4 0.1 0.069 12.1 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2178 PF09946.4 KND95871.1 - 0.15 11.8 0.0 0.16 11.7 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) Pkinase PF00069.20 KND95873.1 - 4.3e-69 232.5 0.0 7.6e-69 231.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND95873.1 - 1.1e-52 178.6 0.0 1.7e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KND95873.1 - 3.1e-20 72.3 1.2 1.2e-19 70.4 0.0 2.6 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 KND95873.1 - 2.6e-07 29.9 0.0 4.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH PF00169.24 KND95873.1 - 0.00014 21.9 0.1 0.00033 20.8 0.0 1.6 1 0 0 1 1 1 1 PH domain APH PF01636.18 KND95873.1 - 0.0023 17.7 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KND95873.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 KND95873.1 - 0.018 13.9 0.1 0.029 13.2 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 KND95873.1 - 0.1 11.6 0.1 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gti1_Pac2 PF09729.4 KND95875.1 - 4.3e-49 166.6 0.0 7.8e-49 165.7 0.0 1.4 1 0 0 1 1 1 1 Gti1/Pac2 family PAT1 PF09770.4 KND95875.1 - 4.3 5.4 23.2 5.7 5.0 16.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 F-box-like PF12937.2 KND95882.1 - 3.5e-05 23.4 0.0 7.5e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KND95882.1 - 0.048 13.3 0.0 0.21 11.2 0.0 2.2 1 0 0 1 1 1 0 F-box domain TFIIE_beta PF02186.10 KND95884.1 - 9.1e-23 80.0 0.0 3.1e-22 78.3 0.0 1.9 2 0 0 2 2 2 1 TFIIE beta subunit core domain Mt_ATP-synt_D PF05873.7 KND95884.1 - 0.011 15.4 0.1 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) NTF2 PF02136.15 KND95885.1 - 9.1e-24 84.1 0.0 9.9e-24 83.9 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain cwf21 PF08312.7 KND95887.1 - 4.3e-13 48.8 18.3 4.3e-13 48.8 12.7 2.6 2 0 0 2 2 2 1 cwf21 domain Macoilin PF09726.4 KND95887.1 - 4.3 5.5 24.6 1.5 6.9 15.3 1.4 1 1 0 1 1 1 0 Transmembrane protein ATG27 PF09451.5 KND95887.1 - 7.1 5.7 9.1 9.1 5.4 6.3 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 His_Phos_2 PF00328.17 KND95889.1 - 3.3e-17 62.8 0.0 6.9e-17 61.7 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) EamA PF00892.15 KND95892.1 - 1.3e-25 89.8 28.5 8.4e-17 61.3 3.8 2.5 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 KND95892.1 - 7.7e-09 35.7 6.9 7.7e-09 35.7 4.8 3.0 2 2 1 3 3 3 1 Multidrug resistance efflux transporter DUF914 PF06027.7 KND95892.1 - 0.0026 16.6 0.6 0.0026 16.6 0.4 2.1 1 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 KND95892.1 - 0.12 12.0 22.2 0.013 15.1 5.5 3.7 2 2 2 4 4 4 0 Triose-phosphate Transporter family DUF4336 PF14234.1 KND95894.1 - 0.02 14.0 0.0 0.14 11.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4336) 4HBT PF03061.17 KND95895.1 - 1.3e-06 28.4 0.0 2.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Asn_synthase PF00733.16 KND95896.1 - 5.6e-45 153.8 0.0 9.3e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KND95896.1 - 2.9e-14 52.8 0.0 1.4e-13 50.7 0.0 2.1 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KND95896.1 - 7.8e-08 32.3 0.0 5.6e-07 29.5 0.0 2.4 2 1 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KND95896.1 - 0.082 12.1 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Aluminium induced protein Glyco_hydro_31 PF01055.21 KND95897.1 - 1.2e-167 558.2 3.8 1.5e-167 557.8 2.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 APC_CDC26 PF10471.4 KND95898.1 - 3.3e-09 37.3 0.1 4.3e-09 36.9 0.1 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 U3_snoRNA_assoc PF08297.6 KND95899.1 - 5.3e-16 58.6 12.7 5.3e-16 58.6 8.8 3.1 2 1 0 2 2 2 1 U3 snoRNA associated SOBP PF15279.1 KND95899.1 - 1.7 8.9 12.7 2.5 8.4 8.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF99 PF01949.11 KND95899.1 - 4.3 6.3 5.6 11 5.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF99 MAT1 PF06391.8 KND95899.1 - 5.5 6.5 30.0 4.8 6.7 19.7 1.7 1 1 1 2 2 2 0 CDK-activating kinase assembly factor MAT1 Herpes_env PF01673.13 KND95899.1 - 6.1 5.2 11.5 7.5 4.9 8.0 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein F-box-like PF12937.2 KND95900.1 - 3.5e-09 36.2 0.7 1.4e-08 34.3 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KND95900.1 - 2.6e-08 33.3 0.8 8.3e-08 31.6 0.5 1.9 1 0 0 1 1 1 1 F-box domain TPR_11 PF13414.1 KND95900.1 - 5.8e-07 29.0 0.1 0.0001 21.8 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KND95900.1 - 5.2e-06 25.8 0.7 0.025 14.1 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KND95900.1 - 1.7e-05 24.3 0.2 0.043 13.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KND95900.1 - 0.00031 21.3 0.0 0.13 13.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat LRR_4 PF12799.2 KND95900.1 - 0.0011 18.4 6.4 2.9 7.5 0.0 4.9 4 3 0 4 4 4 2 Leucine Rich repeats (2 copies) TPR_19 PF14559.1 KND95900.1 - 0.002 18.4 0.7 0.46 10.8 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KND95900.1 - 0.003 17.4 0.2 3.4 7.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat LRR_6 PF13516.1 KND95900.1 - 0.026 14.5 8.9 3.5 7.9 0.1 5.6 5 0 0 5 5 5 0 Leucine Rich repeat TPR_14 PF13428.1 KND95900.1 - 0.1 13.2 0.8 1.3 9.8 0.2 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat LRR_1 PF00560.28 KND95900.1 - 1.1 9.5 6.5 52 4.4 0.0 4.8 4 1 0 4 4 3 0 Leucine Rich Repeat Beta-APP PF03494.8 KND95901.1 - 0.027 13.9 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Zip PF02535.17 KND95902.1 - 3.7e-26 91.8 23.9 1.1e-19 70.5 7.7 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter DUF3336 PF11815.3 KND95903.1 - 4e-41 139.9 1.2 2.4e-40 137.3 1.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KND95903.1 - 4.3e-26 92.1 0.1 1.3e-25 90.4 0.0 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase PLA2_B PF01735.13 KND95905.1 - 5.3e-151 503.1 0.0 6.5e-151 502.8 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.17 KND95905.1 - 0.0091 15.9 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase OSTMP1 PF09777.4 KND95905.1 - 0.037 13.1 1.3 0.044 12.9 0.1 1.7 1 1 1 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor UPF0128 PF03673.8 KND95907.1 - 0.14 11.4 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) Lactamase_B_2 PF12706.2 KND95909.1 - 1.3e-34 119.4 0.2 2.7e-34 118.4 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 KND95909.1 - 2.4e-14 52.5 0.2 5.9e-14 51.2 0.1 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 KND95909.1 - 0.016 14.8 0.1 0.04 13.5 0.0 1.8 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily TPP1 PF10341.4 KND95910.1 - 1.2e-17 63.8 0.0 1.7e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD NUDIX_2 PF13869.1 KND95910.1 - 0.087 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Nucleotide hydrolase Ribosomal_L2_C PF03947.13 KND95913.1 - 3.6e-48 162.6 2.5 6.2e-48 161.8 1.7 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KND95913.1 - 3.4e-26 90.9 0.2 3.4e-26 90.9 0.1 2.5 3 1 0 3 3 3 1 Ribosomal Proteins L2, RNA binding domain OSCP PF00213.13 KND95914.1 - 4.5e-45 153.6 1.7 5.2e-45 153.3 1.2 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Metallophos PF00149.23 KND95915.1 - 1.6e-15 57.0 9.4 2.8e-15 56.2 6.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AhpC-TSA PF00578.16 KND95916.1 - 4.5e-28 97.4 0.0 6.3e-28 96.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KND95916.1 - 6.1e-19 68.0 0.0 8.6e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 KND95916.1 - 0.002 18.0 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF3656 PF12392.3 KND95916.1 - 0.015 15.3 3.3 0.02 14.9 0.1 2.3 2 0 0 2 2 2 0 Collagenase CDC45 PF02724.9 KND95916.1 - 0.11 10.4 5.5 0.12 10.3 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein UPF0560 PF10577.4 KND95916.1 - 1.7 6.8 9.1 2.1 6.5 6.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 C9orf72-like PF15019.1 KND95920.1 - 0.099 11.8 0.9 0.12 11.5 0.6 1.0 1 0 0 1 1 1 0 C9orf72-like protein family DUF4134 PF13572.1 KND95920.1 - 0.13 12.3 1.5 0.19 11.8 0.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4134) Mito_carr PF00153.22 KND95923.1 - 4.9e-63 208.8 2.6 2.3e-21 75.2 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 KND95923.1 - 1.4e-22 77.1 17.6 1.4e-05 24.0 0.3 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KND95923.1 - 8.4e-22 77.0 12.9 1.1e-12 47.8 1.3 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KND95923.1 - 1.4e-19 68.1 16.1 0.00011 21.7 0.2 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 KND95923.1 - 6.7e-18 64.0 11.4 0.00027 20.4 0.0 4.5 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 KND95923.1 - 1.4e-12 46.2 17.9 0.0047 16.2 0.4 4.6 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KND95923.1 - 0.00026 20.8 0.6 0.034 14.0 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.4 KND95923.1 - 0.013 15.5 1.8 0.75 9.8 0.1 2.8 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SinI PF08671.5 KND95923.1 - 0.022 14.1 0.2 9 5.8 0.0 2.8 2 0 0 2 2 2 0 Anti-repressor SinI p25-alpha PF05517.7 KND95923.1 - 0.14 12.4 2.5 6.3 7.0 0.2 3.0 1 1 2 3 3 3 0 p25-alpha HORMA PF02301.13 KND95924.1 - 2.5e-10 40.2 0.0 3.2e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 HORMA domain MutL_C PF08676.6 KND95925.1 - 8.1e-29 100.0 0.2 1.7e-28 99.0 0.1 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 KND95925.1 - 1.2e-21 76.3 0.0 3.3e-21 74.9 0.0 1.8 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KND95925.1 - 5.6e-12 45.4 0.1 1.9e-11 43.7 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KND95925.1 - 2.5e-09 36.8 0.1 7.1e-09 35.3 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Zn_clus PF00172.13 KND95927.1 - 3.2e-07 30.1 9.2 5.5e-07 29.3 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 KND95928.1 - 1.5e-08 34.4 7.3 2.3e-08 33.7 5.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain N2227 PF07942.7 KND95929.1 - 2.7e-79 265.9 0.0 3.3e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 KND95929.1 - 3e-05 23.7 0.0 6.7e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND95929.1 - 0.008 16.6 0.0 0.051 14.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND95929.1 - 0.078 13.4 0.1 0.48 10.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain B5 PF03484.10 KND95929.1 - 0.089 12.6 0.1 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetase B5 domain YflT PF11181.3 KND95929.1 - 0.14 12.3 0.5 0.3 11.2 0.3 1.5 1 0 0 1 1 1 0 Heat induced stress protein YflT Ras PF00071.17 KND95930.1 - 7.8e-60 200.9 0.1 9.1e-60 200.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KND95930.1 - 1.3e-19 70.7 0.0 2.2e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KND95930.1 - 8.6e-15 54.4 0.0 9.7e-15 54.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KND95930.1 - 3.8e-08 32.7 0.0 4.6e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KND95930.1 - 2e-06 27.3 0.0 6.4e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KND95930.1 - 2.6e-05 24.1 0.0 3.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KND95930.1 - 0.0017 18.4 0.1 0.0046 16.9 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain NMT1 PF09084.6 KND95931.1 - 4.7e-21 75.3 0.2 4.3e-20 72.2 0.2 2.0 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.15 KND95931.1 - 9e-06 25.0 0.0 1.8e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.1 KND95931.1 - 4.7e-05 22.9 0.0 0.0001 21.8 0.0 1.6 2 0 0 2 2 2 1 NMT1-like family VitK2_biosynth PF02621.9 KND95931.1 - 0.00056 19.1 0.0 0.00092 18.4 0.0 1.3 1 0 0 1 1 1 1 Menaquinone biosynthesis Phosphonate-bd PF12974.2 KND95931.1 - 0.001 18.5 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein LysR_substrate PF03466.15 KND95931.1 - 0.003 16.6 0.0 0.13 11.3 0.0 2.2 2 0 0 2 2 2 1 LysR substrate binding domain DUF3834 PF12916.2 KND95931.1 - 0.14 11.1 0.1 0.49 9.3 0.0 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3834) Y_phosphatase PF00102.22 KND95932.1 - 1.9e-55 187.7 0.0 3.5e-55 186.9 0.0 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KND95932.1 - 0.00062 19.8 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 KND95932.1 - 0.0013 18.3 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KND95932.1 - 0.094 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family KH_1 PF00013.24 KND95933.1 - 1.4e-10 40.6 0.2 2.8e-10 39.7 0.2 1.5 1 1 0 1 1 1 1 KH domain KH_3 PF13014.1 KND95933.1 - 1.1e-07 31.3 0.2 1.9e-07 30.5 0.2 1.3 1 0 0 1 1 1 1 KH domain KH_2 PF07650.12 KND95933.1 - 0.018 14.5 0.2 0.035 13.6 0.1 1.5 1 0 0 1 1 1 0 KH domain PFU PF09070.6 KND95933.1 - 0.16 11.9 0.1 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) HSP70 PF00012.15 KND95934.1 - 8e-235 780.3 7.5 1e-234 780.0 5.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KND95934.1 - 1.5e-17 63.1 0.1 4.7e-16 58.2 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 KND95934.1 - 0.0012 18.4 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain RIO1 PF01163.17 KND95935.1 - 4.2e-44 150.1 0.8 5.4e-44 149.8 0.1 1.5 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.6 KND95935.1 - 9.3e-30 102.5 0.1 4.5e-29 100.3 0.0 2.2 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.18 KND95935.1 - 5.3e-08 32.9 0.0 0.0061 16.3 0.1 2.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KND95935.1 - 0.00028 20.0 0.0 0.011 14.8 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KND95935.1 - 0.026 13.6 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain DUF2457 PF10446.4 KND95935.1 - 9.1 4.8 24.5 13 4.3 17.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) LRR_4 PF12799.2 KND95937.1 - 0.058 13.0 0.1 0.21 11.2 0.1 1.9 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KND95937.1 - 0.06 13.1 0.5 0.23 11.2 0.2 2.1 2 0 0 2 2 2 0 Leucine rich repeat DCP2 PF05026.8 KND95938.1 - 3.3e-32 110.2 0.1 7.4e-32 109.1 0.1 1.6 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 KND95938.1 - 1.1e-16 60.7 0.0 3.4e-16 59.1 0.0 1.8 1 0 0 1 1 1 1 NUDIX domain ATP-synt_10 PF05176.9 KND95939.1 - 3.7e-71 239.3 0.0 4.5e-71 239.0 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein PQQ PF01011.16 KND95939.1 - 0.029 13.9 0.0 0.073 12.6 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat Ribosomal_S10 PF00338.17 KND95940.1 - 3.8e-29 100.3 0.8 4.8e-29 100.0 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e ACT_4 PF13291.1 KND95940.1 - 0.089 13.1 0.8 1.1 9.6 0.2 2.1 2 0 0 2 2 2 0 ACT domain PP2C PF00481.16 KND95942.1 - 2.7e-42 144.9 0.0 4.8e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KND95942.1 - 0.0049 16.2 0.0 0.01 15.2 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KND95942.1 - 0.1 12.3 0.0 1.2 8.7 0.0 2.4 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) DSHCT PF08148.7 KND95943.1 - 1.1e-62 210.4 0.7 3.2e-62 208.9 0.5 1.9 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KND95943.1 - 1.9e-22 79.5 0.9 5.6e-22 78.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 KND95943.1 - 8.2e-07 28.4 6.9 1.2e-05 24.5 4.8 2.5 1 1 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.26 KND95943.1 - 2.8e-06 27.0 0.0 7.8e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain NuiA PF07924.6 KND95943.1 - 0.034 14.0 0.9 0.12 12.3 0.1 2.3 2 0 0 2 2 2 0 Nuclease A inhibitor-like protein AAA PF00004.24 KND95945.1 - 1.2e-88 294.1 0.0 4.4e-43 146.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KND95945.1 - 1.3e-13 50.5 0.0 2.6e-06 26.6 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KND95945.1 - 7.5e-12 45.6 1.0 4.2e-05 23.6 0.0 4.0 3 1 0 4 4 3 2 AAA ATPase domain AAA_5 PF07728.9 KND95945.1 - 8.2e-11 41.7 0.1 0.00011 21.9 0.0 3.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KND95945.1 - 1.1e-10 41.6 2.1 0.00025 21.1 0.0 4.8 4 2 1 5 5 3 2 AAA domain AAA_14 PF13173.1 KND95945.1 - 1.7e-08 34.4 0.0 0.00063 19.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 KND95945.1 - 2.5e-08 34.0 0.0 0.0043 16.9 0.0 3.2 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 KND95945.1 - 6.5e-07 28.3 0.0 0.019 13.7 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 KND95945.1 - 7.3e-07 28.8 1.2 0.00046 19.8 0.0 3.3 3 0 0 3 3 2 1 Part of AAA domain AAA_33 PF13671.1 KND95945.1 - 7.3e-06 25.9 0.0 0.014 15.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.13 KND95945.1 - 1.3e-05 25.0 0.0 0.022 14.4 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_17 PF13207.1 KND95945.1 - 2e-05 25.4 0.0 0.46 11.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 KND95945.1 - 4.1e-05 22.8 0.5 0.11 11.6 0.1 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KND95945.1 - 7e-05 22.9 0.0 0.46 10.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 KND95945.1 - 0.00022 21.2 0.0 0.65 9.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 KND95945.1 - 0.00024 20.8 0.1 0.066 12.8 0.0 3.7 4 0 0 4 4 4 1 NACHT domain IstB_IS21 PF01695.12 KND95945.1 - 0.00031 20.2 0.0 0.72 9.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 KND95945.1 - 0.00032 20.7 0.0 0.022 14.8 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Rad17 PF03215.10 KND95945.1 - 0.00048 18.9 0.0 0.037 12.7 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Zeta_toxin PF06414.7 KND95945.1 - 0.00052 19.1 0.0 0.84 8.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_3 PF07726.6 KND95945.1 - 0.00074 19.1 0.0 1.1 8.8 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KND95945.1 - 0.00082 18.8 4.7 1.2 8.4 0.0 4.3 2 2 2 4 4 4 1 AAA domain Viral_helicase1 PF01443.13 KND95945.1 - 0.00085 18.9 0.0 0.48 9.9 0.0 3.5 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 KND95945.1 - 0.00098 18.7 0.1 2 7.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 KND95945.1 - 0.003 17.2 0.0 1.3 8.6 0.0 2.8 2 1 1 3 3 3 1 Archaeal ATPase AAA_18 PF13238.1 KND95945.1 - 0.008 16.4 0.0 0.73 10.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain KaiC PF06745.8 KND95945.1 - 0.015 14.4 0.1 4.9 6.2 0.0 2.9 3 0 0 3 3 2 0 KaiC ABC_tran PF00005.22 KND95945.1 - 0.023 14.9 0.0 1.7 8.9 0.0 2.6 2 0 0 2 2 2 0 ABC transporter CDC48_N PF02359.13 KND95945.1 - 0.041 13.8 0.1 0.14 12.0 0.0 1.9 2 0 0 2 2 1 0 Cell division protein 48 (CDC48), N-terminal domain AAA_24 PF13479.1 KND95945.1 - 0.046 13.3 0.3 11 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 KND95945.1 - 0.062 12.2 0.0 5 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) UPF0079 PF02367.12 KND95945.1 - 0.082 12.5 0.1 2.5 7.7 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AFG1_ATPase PF03969.11 KND95945.1 - 0.087 11.6 0.0 0.38 9.4 0.0 1.9 2 0 0 2 2 2 0 AFG1-like ATPase Pex19 PF04614.7 KND95946.1 - 1.3e-75 254.2 18.1 1.3e-75 254.2 12.5 1.9 1 1 1 2 2 2 1 Pex19 protein family PilJ PF13675.1 KND95946.1 - 0.18 12.1 2.7 0.53 10.6 0.1 2.7 3 1 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term BING4CT PF08149.6 KND95946.1 - 0.68 9.4 3.1 0.47 9.9 0.1 2.2 3 0 0 3 3 3 0 BING4CT (NUC141) domain RGCC PF15151.1 KND95946.1 - 3.6 8.0 11.4 5.5 7.4 4.0 3.5 2 1 1 3 3 3 0 Response gene to complement 32 protein family FliE PF02049.13 KND95946.1 - 7.4 6.6 10.7 20 5.3 0.2 3.6 1 1 2 3 3 3 0 Flagellar hook-basal body complex protein FliE UQ_con PF00179.21 KND95947.1 - 3e-44 149.8 0.1 3.4e-44 149.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KND95947.1 - 8.1e-05 22.3 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KND95947.1 - 0.015 14.9 0.4 0.025 14.2 0.3 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 KND95947.1 - 0.5 10.2 2.6 1.4 8.8 1.8 2.0 1 1 0 1 1 1 0 RWD domain 6PF2K PF01591.13 KND95948.1 - 7.8e-77 257.3 0.1 1.1e-76 256.8 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KND95948.1 - 9.5e-32 110.2 0.1 1.6e-31 109.5 0.1 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KND95948.1 - 2.2e-05 24.3 0.0 4.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KND95948.1 - 0.0016 17.7 0.1 0.0022 17.2 0.1 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 KND95948.1 - 0.052 14.3 1.3 0.7 10.7 0.1 2.9 2 1 0 2 2 2 0 AAA domain Peptidase_S64 PF08192.6 KND95949.1 - 1.2e-248 827.0 1.3 1.6e-248 826.6 0.9 1.1 1 0 0 1 1 1 1 Peptidase family S64 DUF3646 PF12362.3 KND95949.1 - 0.06 13.2 0.3 0.15 12.0 0.2 1.5 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal IL32 PF15225.1 KND95952.1 - 0.067 13.1 0.1 0.068 13.1 0.0 1.0 1 0 0 1 1 1 0 Interleukin 32 DUF663 PF04950.7 KND95957.1 - 1.3e-91 306.6 0.2 2.3e-91 305.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KND95957.1 - 3.1e-24 84.3 0.0 6.7e-24 83.2 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain zf-C2H2_2 PF12756.2 KND95958.1 - 2.6e-29 101.2 3.3 6.6e-29 100.0 2.3 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KND95958.1 - 4.3 7.6 8.7 16 5.7 2.1 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DnaJ PF00226.26 KND95960.1 - 1.6e-19 69.3 0.7 3.1e-19 68.4 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KND95960.1 - 1.8e-10 40.5 6.9 9.1e-07 28.6 2.2 4.0 2 1 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KND95960.1 - 4.7e-10 39.3 13.7 4.7e-10 39.3 9.5 2.0 2 0 0 2 2 2 1 DnaJ central domain Vac14_Fig4_bd PF11916.3 KND95961.1 - 3e-65 218.7 11.1 6.7e-65 217.6 7.7 1.6 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 KND95961.1 - 2.4e-35 120.8 0.6 1.3e-34 118.4 0.2 2.5 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 KND95961.1 - 0.00015 22.0 0.4 0.0057 16.9 0.0 3.8 5 1 1 6 6 6 1 HEAT repeats HEAT PF02985.17 KND95961.1 - 0.00052 19.8 0.0 0.026 14.5 0.0 3.4 2 0 0 2 2 2 1 HEAT repeat HEAT_EZ PF13513.1 KND95961.1 - 0.0015 18.9 0.1 0.58 10.7 0.0 4.2 5 0 0 5 5 5 1 HEAT-like repeat Pyr_redox_3 PF13738.1 KND95964.1 - 8.8e-09 35.7 0.0 1.5e-05 25.1 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KND95964.1 - 0.00016 21.4 0.0 0.0012 18.6 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KND95964.1 - 0.00043 20.2 0.0 0.0033 17.3 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND95964.1 - 0.0092 16.3 0.9 9.3 6.7 0.0 3.4 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KND95964.1 - 0.024 14.6 0.0 0.24 11.4 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lipase_3 PF01764.20 KND95965.1 - 5e-35 120.1 0.0 7.5e-35 119.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 KND95965.1 - 0.00012 21.4 0.0 0.54 9.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.15 KND95965.1 - 0.04 13.4 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.9 KND95965.1 - 0.057 12.6 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.8 KND95965.1 - 0.081 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.15 KND95965.1 - 0.12 11.7 0.0 0.83 9.0 0.0 2.0 1 1 1 2 2 2 0 Putative esterase UPF0203 PF05254.7 KND95966.1 - 9.2e-30 102.3 2.1 1.1e-29 102.0 1.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 KND95966.1 - 6e-05 22.7 1.8 0.18 11.5 0.1 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 KND95966.1 - 0.078 12.9 2.1 0.21 11.5 1.4 1.6 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein COX6B PF02297.12 KND95966.1 - 0.19 11.7 4.7 2.2 8.3 0.1 2.0 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb TK PF00265.13 KND95967.1 - 0.099 12.1 0.1 0.099 12.1 0.1 1.0 1 0 0 1 1 1 0 Thymidine kinase DASH_Ask1 PF08655.5 KND95968.1 - 4.4e-22 77.6 1.0 1.4e-21 76.0 0.1 2.2 2 0 0 2 2 2 1 DASH complex subunit Ask1 Fe_dep_repr_C PF02742.10 KND95968.1 - 0.09 12.4 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain MCM PF00493.18 KND95969.1 - 5.6e-129 429.6 0.2 1e-128 428.8 0.1 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KND95969.1 - 1.5e-18 67.4 0.0 4.9e-18 65.7 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KND95969.1 - 1.8e-08 33.8 0.5 3e-07 29.7 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KND95969.1 - 0.0016 17.9 0.0 0.0059 16.1 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 KND95969.1 - 0.0017 17.9 0.0 0.0041 16.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KND95969.1 - 0.04 13.6 0.0 0.41 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Methyltransf_15 PF09445.5 KND95970.1 - 4.5e-47 159.6 0.1 5.7e-47 159.3 0.1 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.1 KND95970.1 - 7.3e-13 48.3 0.0 9.9e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND95970.1 - 2.3e-11 43.7 0.0 2.9e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND95970.1 - 4.9e-11 42.8 0.1 7.8e-11 42.2 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND95970.1 - 2.3e-10 41.0 0.0 4.4e-10 40.1 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain UPF0020 PF01170.13 KND95970.1 - 1.4e-08 34.4 0.0 2.2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.7 KND95970.1 - 3.1e-06 27.5 0.0 5.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 KND95970.1 - 2.6e-05 23.4 0.0 3.7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Ubie_methyltran PF01209.13 KND95970.1 - 2.9e-05 23.3 0.0 4.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KND95970.1 - 0.00011 21.4 1.5 0.00022 20.4 0.2 1.8 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 KND95970.1 - 0.00016 21.0 0.0 0.00025 20.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.10 KND95970.1 - 0.0019 17.6 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.1 KND95970.1 - 0.0062 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KND95970.1 - 0.014 14.9 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Nol1_Nop2_Fmu PF01189.12 KND95970.1 - 0.017 14.4 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 NOL1/NOP2/sun family PrmA PF06325.8 KND95970.1 - 0.024 13.7 0.0 0.032 13.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pox_MCEL PF03291.11 KND95970.1 - 0.026 13.3 0.2 0.041 12.7 0.1 1.2 1 0 0 1 1 1 0 mRNA capping enzyme Methyltransf_12 PF08242.7 KND95970.1 - 0.037 14.4 0.0 0.084 13.3 0.0 1.6 2 0 0 2 2 1 0 Methyltransferase domain PCMT PF01135.14 KND95970.1 - 0.045 13.2 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MFS_1 PF07690.11 KND95971.1 - 9.4e-19 67.3 24.4 1.4e-18 66.7 16.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KND95971.1 - 6e-05 22.7 2.2 6e-05 22.7 1.5 2.4 3 0 0 3 3 3 1 MFS_1 like family DEAD PF00270.24 KND95972.1 - 4.1e-38 130.5 0.1 1.7e-37 128.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND95972.1 - 2.3e-18 65.8 0.3 5e-18 64.7 0.2 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND95972.1 - 6.4e-08 32.6 0.0 6.4e-08 32.6 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 KND95972.1 - 0.014 14.7 1.0 0.037 13.3 0.0 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 KND95972.1 - 0.018 15.1 0.3 0.086 12.9 0.2 2.1 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 KND95972.1 - 0.041 13.6 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain BUD22 PF09073.5 KND95972.1 - 1.3 7.9 20.1 2 7.3 13.9 1.1 1 0 0 1 1 1 0 BUD22 FGF-BP1 PF06473.7 KND95972.1 - 5.2 6.5 7.8 9.2 5.7 5.4 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Daxx PF03344.10 KND95972.1 - 9.2 4.6 21.0 13 4.1 14.5 1.1 1 0 0 1 1 1 0 Daxx Family Ribosomal_S19 PF00203.16 KND95973.1 - 8e-23 79.8 0.0 9.7e-23 79.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 PP2C PF00481.16 KND95974.1 - 4.6e-32 111.4 0.0 1.6e-27 96.5 0.0 3.5 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 KND95974.1 - 3.7e-05 23.2 0.0 8.2e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KND95974.1 - 0.031 13.9 0.1 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Ligase_CoA PF00549.14 KND95974.1 - 0.034 13.7 0.1 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 CoA-ligase Glutaredoxin PF00462.19 KND95975.1 - 4.6e-19 68.1 0.1 6.1e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 KND95975.1 - 0.0003 20.5 0.0 0.00046 19.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_4 PF13462.1 KND95975.1 - 0.003 17.5 0.3 1.4 8.9 0.1 2.1 2 0 0 2 2 2 2 Thioredoxin DUF836 PF05768.9 KND95975.1 - 0.006 16.8 0.0 0.0079 16.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 KND95975.1 - 0.007 16.5 0.1 0.0097 16.0 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.1 KND95975.1 - 0.011 15.1 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.1 KND95975.1 - 0.018 14.5 0.0 0.022 14.3 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin DSBA PF01323.15 KND95975.1 - 0.028 13.9 0.3 2 7.9 0.1 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Glyoxalase PF00903.20 KND95976.1 - 5e-35 120.2 0.0 1.4e-17 63.8 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KND95976.1 - 1.3e-29 102.9 0.2 3.7e-15 56.4 0.0 2.3 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KND95976.1 - 9.5e-16 57.7 0.0 4.7e-08 33.0 0.0 3.9 1 1 2 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.1 KND95976.1 - 0.00019 21.0 0.0 0.65 9.6 0.0 2.4 2 0 0 2 2 2 2 CppA N-terminal Glyoxalase_3 PF13468.1 KND95976.1 - 0.0067 16.3 0.0 0.053 13.4 0.0 2.3 3 0 0 3 3 3 1 Glyoxalase-like domain Pantoate_transf PF02548.10 KND95977.1 - 2.2e-103 344.9 0.6 2.7e-103 344.6 0.4 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 KND95977.1 - 3.1e-10 39.6 0.9 1.4e-09 37.5 0.6 2.1 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Dus PF01207.12 KND95980.1 - 1.6e-72 243.9 0.0 2.2e-72 243.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Abhydrolase_2 PF02230.11 KND95981.1 - 5.5e-56 189.4 0.1 6.2e-56 189.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KND95981.1 - 6.4e-12 45.4 0.0 1.7e-11 44.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KND95981.1 - 4.3e-09 36.1 0.0 1.5e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KND95981.1 - 2e-07 31.1 0.0 2.4e-05 24.3 0.0 2.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 KND95981.1 - 1.4e-05 24.5 0.0 1.9e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Cutinase PF01083.17 KND95981.1 - 0.00048 19.9 0.0 0.00075 19.2 0.0 1.4 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 KND95981.1 - 0.00059 19.4 0.0 0.00082 18.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KND95981.1 - 0.0018 17.9 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KND95981.1 - 0.059 12.5 0.3 9 5.4 0.0 2.7 2 1 1 3 3 3 0 Prolyl oligopeptidase family Lipase_3 PF01764.20 KND95981.1 - 0.064 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.15 KND95981.1 - 0.092 12.1 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase AXE1 PF05448.7 KND95981.1 - 0.11 10.9 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Dopey_N PF04118.9 KND95982.1 - 5e-110 367.0 1.9 5e-110 367.0 1.3 2.5 2 0 0 2 2 2 1 Dopey, N-terminal RRM_1 PF00076.17 KND95984.1 - 1.3e-06 27.8 0.1 0.00029 20.3 0.1 2.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND95984.1 - 2.6e-06 27.3 0.1 1.1e-05 25.2 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND95984.1 - 4.1e-06 26.5 0.4 8e-05 22.4 0.3 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Macoilin PF09726.4 KND95984.1 - 0.39 8.9 15.6 0.037 12.3 4.0 2.0 2 0 0 2 2 2 0 Transmembrane protein HSP9_HSP12 PF04119.7 KND95985.1 - 9e-27 92.9 2.0 9e-27 92.9 1.4 2.2 2 1 0 2 2 2 1 Heat shock protein 9/12 DUF1318 PF07027.7 KND95985.1 - 0.025 14.8 0.9 0.05 13.8 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1318) Tape_meas_lam_C PF09718.5 KND95985.1 - 0.31 10.9 2.2 0.8 9.6 0.6 2.1 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) YtxH PF12732.2 KND95985.1 - 1.1 9.6 9.9 20 5.6 6.9 2.4 1 1 0 1 1 1 0 YtxH-like protein DUF883 PF05957.8 KND95985.1 - 1.6 9.1 5.3 4.1 7.8 3.3 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) AAA PF00004.24 KND95987.1 - 1.8e-92 306.4 0.0 8.5e-47 158.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KND95987.1 - 1.6e-15 56.8 0.0 8.3e-09 34.8 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KND95987.1 - 1.2e-13 51.9 0.5 2.9e-08 34.5 0.0 3.8 3 0 0 3 3 3 2 AAA domain AAA_2 PF07724.9 KND95987.1 - 9.2e-13 48.4 0.0 7.9e-05 22.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KND95987.1 - 6.9e-12 45.6 1.1 0.004 17.2 0.0 5.2 3 2 0 3 3 3 2 AAA domain AAA_14 PF13173.1 KND95987.1 - 5.2e-11 42.5 0.0 5.4e-05 23.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KND95987.1 - 1.1e-10 41.8 0.3 0.001 19.1 0.1 3.6 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 KND95987.1 - 3.2e-10 40.0 0.0 0.00097 19.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KND95987.1 - 5.9e-10 38.5 0.0 0.0011 18.1 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_5 PF07728.9 KND95987.1 - 1.6e-09 37.6 0.3 0.0022 17.6 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KND95987.1 - 5.8e-09 35.1 0.0 0.00014 20.6 0.0 2.7 2 0 0 2 2 2 2 TIP49 C-terminus AAA_18 PF13238.1 KND95987.1 - 1.4e-08 35.0 2.1 5.9e-05 23.3 0.0 3.9 3 2 0 3 3 2 2 AAA domain AAA_28 PF13521.1 KND95987.1 - 3.1e-08 33.7 0.0 0.00063 19.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KND95987.1 - 7.4e-08 32.5 0.1 0.0067 16.5 0.0 3.2 3 0 0 3 3 2 2 RNA helicase IstB_IS21 PF01695.12 KND95987.1 - 2.3e-07 30.3 0.7 0.034 13.5 0.0 3.0 3 0 0 3 3 3 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 KND95987.1 - 2.7e-07 29.9 0.3 0.017 14.2 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KND95987.1 - 3.5e-07 29.8 0.5 0.023 14.4 0.0 3.0 2 1 0 2 2 2 2 Part of AAA domain ABC_tran PF00005.22 KND95987.1 - 5.2e-07 30.0 0.4 0.046 14.0 0.0 3.4 3 1 0 3 3 3 2 ABC transporter Cytidylate_kin2 PF13189.1 KND95987.1 - 1.2e-06 28.5 0.0 0.00085 19.2 0.0 3.3 3 0 0 3 3 3 1 Cytidylate kinase-like family AAA_25 PF13481.1 KND95987.1 - 1.8e-06 27.5 4.8 0.18 11.1 0.0 4.4 2 2 2 4 4 4 1 AAA domain SKI PF01202.17 KND95987.1 - 3e-06 27.2 0.2 0.017 15.0 0.0 3.0 3 0 0 3 3 2 2 Shikimate kinase AAA_3 PF07726.6 KND95987.1 - 6.7e-06 25.7 0.0 0.042 13.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KND95987.1 - 1.3e-05 24.1 0.0 0.0037 16.0 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 KND95987.1 - 4.7e-05 22.3 0.2 0.63 8.8 0.0 3.3 3 0 0 3 3 3 2 NB-ARC domain NACHT PF05729.7 KND95987.1 - 5.5e-05 22.8 0.7 0.56 9.8 0.0 3.5 3 1 1 4 4 3 2 NACHT domain Arch_ATPase PF01637.13 KND95987.1 - 6.6e-05 22.7 1.1 0.45 10.1 0.0 4.1 3 2 1 4 4 4 1 Archaeal ATPase KaiC PF06745.8 KND95987.1 - 8.8e-05 21.7 0.5 1.6 7.7 0.0 3.8 4 0 0 4 4 3 2 KaiC AAA_24 PF13479.1 KND95987.1 - 0.0001 21.9 0.1 0.11 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Vps4_C PF09336.5 KND95987.1 - 0.00027 20.7 0.1 0.07 13.0 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Sigma54_activat PF00158.21 KND95987.1 - 0.00049 19.6 0.0 0.22 10.9 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KND95987.1 - 0.00052 20.0 0.1 1.6 8.8 0.0 2.9 3 0 0 3 3 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KND95987.1 - 0.00092 18.1 0.1 0.68 8.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NTPase_1 PF03266.10 KND95987.1 - 0.0011 18.7 0.7 1.5 8.5 0.0 3.2 3 1 0 3 3 2 1 NTPase DUF815 PF05673.8 KND95987.1 - 0.0012 17.8 0.0 0.15 10.9 0.0 2.7 3 0 0 3 3 2 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 KND95987.1 - 0.0012 18.4 0.0 0.52 9.7 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ATP-synt_ab PF00006.20 KND95987.1 - 0.0015 18.0 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_11 PF13086.1 KND95987.1 - 0.0017 17.9 2.6 2.4 7.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain PhoH PF02562.11 KND95987.1 - 0.0053 16.0 0.3 0.99 8.5 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein PduV-EutP PF10662.4 KND95987.1 - 0.0056 16.1 0.0 1.8 8.0 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Bac_DnaA PF00308.13 KND95987.1 - 0.0059 16.2 0.0 1.9 8.0 0.0 3.9 3 1 0 3 3 3 1 Bacterial dnaA protein KTI12 PF08433.5 KND95987.1 - 0.0071 15.5 9.0 3 6.9 0.0 4.1 4 0 0 4 4 4 0 Chromatin associated protein KTI12 IPT PF01745.11 KND95987.1 - 0.018 14.2 0.0 1.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase MMR_HSR1 PF01926.18 KND95987.1 - 0.023 14.6 0.7 1.6 8.7 0.0 3.5 3 1 0 3 3 3 0 50S ribosome-binding GTPase UPF0079 PF02367.12 KND95987.1 - 0.026 14.1 0.0 3.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PAS_10 PF13596.1 KND95987.1 - 0.027 14.7 0.2 5.3 7.3 0.0 3.1 3 0 0 3 3 2 0 PAS domain T2SE PF00437.15 KND95987.1 - 0.03 13.2 0.0 1.7 7.4 0.0 2.8 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_29 PF13555.1 KND95987.1 - 0.051 13.1 0.0 0.9 9.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain ADK PF00406.17 KND95987.1 - 0.058 13.2 2.6 1.5 8.6 0.0 3.0 3 0 0 3 3 3 0 Adenylate kinase FeoB_N PF02421.13 KND95987.1 - 0.063 12.5 0.2 1.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B CPT PF07931.7 KND95987.1 - 0.07 12.7 0.0 0.71 9.4 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF258 PF03193.11 KND95987.1 - 0.11 11.7 0.0 2.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 KND95987.1 - 0.12 11.9 0.1 21 4.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KND95987.1 - 0.14 11.5 2.9 6.5 6.0 0.0 3.5 4 0 0 4 4 2 0 AAA-like domain AAA_23 PF13476.1 KND95987.1 - 0.2 11.9 0.0 0.2 11.9 0.0 3.6 4 0 0 4 4 2 0 AAA domain ResIII PF04851.10 KND95987.1 - 0.29 10.9 3.0 10 5.8 0.0 3.2 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit Abhydrolase_6 PF12697.2 KND95988.1 - 2.9e-33 115.6 0.0 3.9e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND95988.1 - 8.1e-18 64.8 0.0 2.7e-17 63.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KND95988.1 - 4.4e-13 49.2 0.0 1.3e-12 47.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KND95988.1 - 5.7e-05 22.8 0.0 8.5e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 KND95988.1 - 0.021 14.6 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Esterase PF00756.15 KND95988.1 - 0.048 13.0 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF3141 PF11339.3 KND95988.1 - 0.16 10.2 0.0 0.22 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) CN_hydrolase PF00795.17 KND95990.1 - 4.5e-28 97.8 0.0 6.8e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase SBBP PF06739.6 KND95990.1 - 0.041 13.6 4.4 2.8 7.7 0.0 2.9 2 1 0 2 2 2 0 Beta-propeller repeat MFS_1 PF07690.11 KND95993.1 - 2.1e-37 128.6 84.2 1.5e-34 119.3 36.9 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TraG_N PF07916.6 KND95994.1 - 0.83 8.0 3.0 0.87 7.9 2.1 1.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Mannosyl_trans3 PF11051.3 KND95995.1 - 7.2e-82 274.7 0.1 9.8e-82 274.3 0.1 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Shikimate_dh_N PF08501.6 KND95996.1 - 1.4e-18 66.7 0.0 8.2e-18 64.2 0.0 2.3 2 1 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KND95996.1 - 2e-10 40.9 0.0 3.2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DSPc PF00782.15 KND95996.1 - 0.082 12.4 0.0 0.18 11.3 0.0 1.6 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain YoaP PF14268.1 KND95996.1 - 0.11 11.7 0.0 11 5.3 0.0 2.5 2 0 0 2 2 2 0 YoaP-like UPF0061 PF02696.9 KND95997.1 - 4.9e-115 384.6 0.3 6e-115 384.3 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family CdhD PF03599.11 KND95997.1 - 0.17 10.3 0.3 0.38 9.1 0.1 1.6 2 0 0 2 2 2 0 CO dehydrogenase/acetyl-CoA synthase delta subunit SH3_9 PF14604.1 KND96000.1 - 2.1e-10 40.0 0.1 9.7e-10 37.8 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KND96000.1 - 6.9e-08 31.7 0.1 1.3e-07 30.9 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KND96000.1 - 1.1e-07 31.2 0.0 2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF4131 PF13567.1 KND96002.1 - 0.014 14.8 0.3 0.019 14.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) AOX PF01786.12 KND96004.1 - 1.1e-85 286.2 0.3 1.4e-85 285.9 0.2 1.1 1 0 0 1 1 1 1 Alternative oxidase Aa_trans PF01490.13 KND96005.1 - 1.1e-92 310.6 23.1 1.3e-92 310.4 16.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UPF0060 PF02694.10 KND96005.1 - 0.14 12.2 0.1 0.14 12.2 0.1 3.0 4 0 0 4 4 4 0 Uncharacterised BCR, YnfA/UPF0060 family DUF3377 PF11857.3 KND96006.1 - 0.12 12.0 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Peptidase_M24 PF00557.19 KND96009.1 - 3.8e-46 157.2 0.2 4.8e-46 156.9 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 BLVR PF06375.6 KND96009.1 - 0.014 15.1 6.7 0.15 11.8 2.6 2.2 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) PurA PF04845.8 KND96009.1 - 0.053 12.6 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 PurA ssDNA and RNA-binding protein HD_5 PF13487.1 KND96009.1 - 0.063 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 HD domain Glycos_transf_1 PF00534.15 KND96012.1 - 1.2e-12 47.5 0.0 2.2e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KND96012.1 - 0.0011 19.1 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Coatomer_WDAD PF04053.9 KND96013.1 - 2.1e-162 540.9 2.9 3.4e-162 540.2 2.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 KND96013.1 - 9.6e-47 155.2 5.2 4.6e-09 35.8 0.0 8.4 9 0 0 9 9 9 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 KND96013.1 - 0.00029 20.5 0.1 0.18 11.5 0.0 3.9 2 2 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 KND96013.1 - 0.0028 15.8 5.0 0.033 12.3 0.1 3.6 2 2 0 3 3 3 2 Nucleoporin Nup120/160 FtsJ PF01728.14 KND96014.1 - 8.5e-25 87.7 0.0 1.3e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 KND96014.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.13 KND96015.1 - 1.2e-18 66.9 1.4 2.5e-18 65.9 1.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND96015.1 - 4.9e-05 23.1 14.0 0.00011 21.9 9.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_6 PF14259.1 KND96017.1 - 0.00011 22.1 0.0 0.01 15.7 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KND96017.1 - 0.00014 21.4 0.0 0.036 13.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND96017.1 - 0.0036 17.1 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.22 KND96018.1 - 4.7e-32 109.5 8.9 2.5e-13 49.5 0.0 3.5 2 1 2 4 4 4 4 Mitochondrial carrier protein TPT PF03151.11 KND96019.1 - 1.2e-26 93.2 9.6 1.4e-26 93.0 6.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family GtrA PF04138.9 KND96019.1 - 0.02 14.8 2.1 0.02 14.8 1.5 2.5 2 1 1 3 3 3 0 GtrA-like protein DUF2518 PF10726.4 KND96019.1 - 0.046 13.2 0.7 0.046 13.2 0.5 1.8 2 0 0 2 2 2 0 Protein of function (DUF2518) EamA PF00892.15 KND96019.1 - 0.082 12.9 12.1 0.09 12.8 5.8 2.1 2 0 0 2 2 2 0 EamA-like transporter family 60KD_IMP PF02096.15 KND96019.1 - 0.097 12.3 2.3 0.13 11.9 1.6 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein Polysacc_synt PF01943.12 KND96019.1 - 2.6 7.2 15.2 0.37 10.0 7.2 1.7 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein PG_binding_4 PF12229.3 KND96021.1 - 0.08 13.1 0.0 0.094 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Cucumo_2B PF03263.8 KND96022.1 - 0.0032 17.7 2.6 0.015 15.5 0.0 2.0 2 0 0 2 2 2 1 Cucumovirus protein 2B Na_H_Exchanger PF00999.16 KND96023.1 - 3.4e-65 220.0 38.4 4.5e-65 219.6 26.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Metal_CEHH PF14455.1 KND96023.1 - 0.14 11.5 0.0 0.6 9.4 0.0 1.9 2 0 0 2 2 2 0 Predicted metal binding domain Ndc1_Nup PF09531.5 KND96024.1 - 8.4e-123 410.8 13.4 9.6e-123 410.7 9.3 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup F_actin_bind PF08919.5 KND96024.1 - 0.062 13.0 0.7 3.2 7.5 0.0 3.1 2 1 1 3 3 3 0 F-actin binding ERCC4 PF02732.10 KND96026.1 - 2.5e-22 79.1 0.8 5.3e-22 78.1 0.5 1.6 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 KND96026.1 - 0.0077 16.3 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF3470 PF11953.3 KND96027.1 - 0.17 11.4 2.9 21 4.7 0.2 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3470) PRP3 PF08572.5 KND96028.1 - 9.1e-61 205.0 10.9 1.3e-60 204.5 7.6 1.2 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 KND96028.1 - 1.6e-35 121.5 0.1 4.3e-35 120.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DUF3284 PF11687.3 KND96028.1 - 0.078 12.7 0.9 0.14 11.8 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3284) MEA1 PF06910.6 KND96029.1 - 0.066 12.8 0.8 0.062 12.9 0.5 1.1 1 0 0 1 1 1 0 Male enhanced antigen 1 (MEA1) ADH_N PF08240.7 KND96030.1 - 9.7e-26 89.6 1.6 2.2e-25 88.5 1.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KND96030.1 - 3.1e-17 62.3 0.0 5.5e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KND96030.1 - 2.4e-10 41.3 0.0 4.5e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KND96030.1 - 4.1e-05 23.2 0.0 8.2e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 KND96030.1 - 0.0093 16.2 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 KND96030.1 - 0.025 14.6 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 KND96030.1 - 0.028 13.4 0.1 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain SIS_2 PF13580.1 KND96030.1 - 0.028 14.1 0.7 4.1 7.1 0.0 2.5 2 1 1 3 3 3 0 SIS domain 2-Hacid_dh_C PF02826.14 KND96030.1 - 0.031 13.4 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.15 KND96030.1 - 0.05 13.5 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ThiF PF00899.16 KND96030.1 - 0.054 13.3 0.1 0.054 13.3 0.1 1.7 2 0 0 2 2 2 0 ThiF family Methyltransf_23 PF13489.1 KND96030.1 - 0.058 13.1 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.13 KND96030.1 - 0.091 12.7 0.1 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Ribonuc_red_lgC PF02867.10 KND96031.1 - 7.6e-217 721.1 0.0 9.1e-217 720.8 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KND96031.1 - 4.7e-11 42.3 0.0 1.2e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain NRDD PF13597.1 KND96031.1 - 0.00053 18.1 0.0 0.00077 17.6 0.0 1.2 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase OPT PF03169.10 KND96033.1 - 1.5e-183 611.6 54.5 1.7e-183 611.4 37.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein LCCL PF03815.14 KND96035.1 - 4.4e-05 23.3 0.0 8.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 LCCL domain Coatomer_E PF04733.9 KND96036.1 - 1.7e-16 60.2 3.6 1.6e-14 53.8 0.6 2.2 2 0 0 2 2 2 2 Coatomer epsilon subunit Septin PF00735.13 KND96037.1 - 6.1e-77 258.3 0.8 6.1e-77 258.3 0.6 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KND96037.1 - 8.5e-07 28.9 0.1 1.8e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 KND96037.1 - 0.0022 18.3 0.1 0.0066 16.7 0.0 1.9 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 KND96037.1 - 0.0024 17.0 0.0 0.0049 16.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KND96037.1 - 0.0033 16.5 0.5 0.0079 15.3 0.0 1.9 2 0 0 2 2 2 1 AIG1 family AAA_29 PF13555.1 KND96037.1 - 0.011 15.2 0.1 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KND96037.1 - 0.06 12.7 0.1 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 KND96037.1 - 0.073 13.5 0.0 0.21 12.1 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_10 PF12846.2 KND96037.1 - 0.088 12.2 0.3 0.088 12.2 0.2 1.8 2 0 0 2 2 2 0 AAA-like domain DUF676 PF05057.9 KND96039.1 - 1.5e-30 106.1 0.0 2.4e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 KND96039.1 - 9.7e-06 25.2 0.1 2.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 KND96039.1 - 0.028 14.0 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.15 KND96039.1 - 0.077 12.5 1.3 0.45 10.0 0.9 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Asp PF00026.18 KND96039.1 - 0.13 11.4 1.0 1.7 7.8 0.1 2.1 2 0 0 2 2 2 0 Eukaryotic aspartyl protease DUF500 PF04366.7 KND96040.1 - 9.8e-32 109.0 0.0 1.5e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 KND96040.1 - 9.6e-17 60.1 0.1 1.6e-16 59.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KND96040.1 - 5.5e-13 48.2 0.1 1e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KND96040.1 - 8.3e-12 44.4 0.0 1.7e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Arm PF00514.18 KND96041.1 - 2.1e-62 205.0 34.7 1.3e-10 40.6 0.0 11.3 11 1 0 11 11 11 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KND96041.1 - 4.4e-18 65.3 11.0 1.3e-06 28.5 0.2 7.0 1 1 7 8 8 8 7 HEAT repeats HEAT_EZ PF13513.1 KND96041.1 - 5.6e-11 42.5 20.0 0.00053 20.4 0.5 7.4 7 1 2 9 9 9 4 HEAT-like repeat Adaptin_N PF01602.15 KND96041.1 - 8.8e-11 40.8 6.2 1.4e-05 23.6 1.7 2.3 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.7 KND96041.1 - 9.8e-11 40.3 7.5 5.8e-07 27.8 1.0 2.4 1 1 2 3 3 3 3 Kinesin-associated protein (KAP) HEAT PF02985.17 KND96041.1 - 3.9e-08 32.7 25.5 0.043 13.8 0.0 9.5 11 1 0 11 11 11 3 HEAT repeat Arm_2 PF04826.8 KND96041.1 - 1.9e-06 27.1 10.2 0.0001 21.5 1.9 3.0 2 1 0 3 3 3 2 Armadillo-like Vac14_Fab1_bd PF12755.2 KND96041.1 - 0.00014 22.2 0.1 0.74 10.2 0.0 3.0 2 1 0 2 2 2 2 Vacuolar 14 Fab1-binding region Snf7 PF03357.16 KND96042.1 - 1.9e-16 59.9 15.8 3.8e-16 58.9 10.9 1.5 1 1 0 1 1 1 1 Snf7 PspB PF06667.7 KND96042.1 - 0.0056 16.5 0.4 0.025 14.5 0.1 2.3 2 0 0 2 2 2 1 Phage shock protein B Baculo_LEF-11 PF06385.7 KND96042.1 - 0.0064 16.5 1.3 0.023 14.7 0.2 2.3 1 1 1 2 2 2 1 Baculovirus LEF-11 protein ParA PF10609.4 KND96043.1 - 8e-36 121.7 0.0 3.6e-35 119.6 0.0 1.9 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 KND96043.1 - 6.3e-16 58.3 0.0 9.4e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KND96043.1 - 7.6e-08 32.4 0.0 7.2e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 KND96043.1 - 7.8e-07 28.4 0.0 1.7e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 KND96043.1 - 5.9e-05 22.2 0.2 0.00056 19.0 0.0 2.2 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.1 KND96043.1 - 0.0009 18.8 0.0 0.19 11.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KND96043.1 - 0.0022 17.4 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KND96043.1 - 0.0092 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Zn_Tnp_IS1595 PF12760.2 KND96043.1 - 0.13 12.0 0.5 0.5 10.2 0.2 2.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain AAA_19 PF13245.1 KND96043.1 - 0.18 11.5 0.2 1.8 8.3 0.0 2.3 2 1 0 2 2 2 0 Part of AAA domain Nucleoporin2 PF04096.9 KND96044.1 - 7e-36 123.1 0.3 2.3e-35 121.4 0.0 2.1 2 0 0 2 2 2 1 Nucleoporin autopeptidase Nup96 PF12110.3 KND96044.1 - 2.9e-32 111.9 0.7 1.7e-30 106.1 0.5 2.4 1 1 0 1 1 1 1 Nuclear protein 96 Nucleoporin_FG PF13634.1 KND96044.1 - 3.9e-16 59.2 118.6 1.2e-08 35.1 34.3 4.2 1 1 2 3 3 3 3 Nucleoporin FG repeat region YjeF_N PF03853.10 KND96045.1 - 6.1e-27 94.2 0.0 9.5e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 KND96045.1 - 8.7e-08 32.6 4.3 8.7e-08 32.6 3.0 2.3 2 0 0 2 2 2 1 FDF domain LSM PF01423.17 KND96045.1 - 0.002 17.6 0.1 0.0096 15.4 0.0 2.1 2 0 0 2 2 2 1 LSM domain Kinesin PF00225.18 KND96046.1 - 1.3e-96 323.2 1.5 1.5e-96 323.0 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Exonuc_VII_L PF02601.10 KND96046.1 - 7 5.7 10.2 11 5.1 7.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF972 PF06156.8 KND96046.1 - 8.2 6.8 14.5 8.8 6.7 4.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DUF1461 PF07314.6 KND96050.1 - 0.13 12.0 4.8 2.5 7.8 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1461) DUF843 PF05814.6 KND96050.1 - 1.2 9.0 5.4 9.1 6.1 0.1 2.8 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Tic20 PF09685.5 KND96050.1 - 1.9 8.4 8.4 0.26 11.2 1.9 2.2 3 0 0 3 3 3 0 Tic20-like protein UBX PF00789.15 KND96051.1 - 4.2e-09 36.3 0.0 1.2e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 UBX domain PALP PF00291.20 KND96053.1 - 1.8e-61 208.0 0.0 2.3e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 KND96053.1 - 8.8e-15 54.2 0.0 7.3e-11 41.6 0.0 2.6 2 0 0 2 2 2 2 CBS domain TFIIS_M PF07500.9 KND96054.1 - 5.4e-29 100.5 2.7 5.4e-29 100.5 1.9 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 KND96054.1 - 4.4e-18 64.6 7.6 6.8e-18 64.0 5.3 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 KND96054.1 - 2.5e-15 55.7 1.1 2.5e-15 55.7 0.8 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.3 KND96054.1 - 0.0047 16.2 2.3 0.0077 15.6 1.6 1.3 1 0 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain Elf1 PF05129.8 KND96054.1 - 0.014 15.0 2.4 0.032 13.9 1.7 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 KND96054.1 - 1.1 9.1 6.6 6 6.7 4.7 2.0 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Ribosomal_S27 PF01599.14 KND96054.1 - 4.2 7.2 6.7 3.4 7.5 0.6 2.4 1 1 1 2 2 2 0 Ribosomal protein S27a RRM_1 PF00076.17 KND96055.1 - 3.4e-16 58.6 0.0 7.2e-16 57.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND96055.1 - 7.4e-15 54.6 0.0 2.2e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.1 KND96055.1 - 1.1e-12 47.8 3.7 1.8e-12 47.1 2.5 1.3 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_5 PF13893.1 KND96055.1 - 5.2e-06 26.2 0.0 1.2e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aldo_ket_red PF00248.16 KND96060.1 - 1.8e-32 112.3 0.0 2.3e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 KND96061.1 - 6.1e-19 67.9 64.1 7.4e-15 54.5 22.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Inhibitor_I10 PF12559.3 KND96061.1 - 0.081 13.2 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Serine endopeptidase inhibitors Flavi_M PF01004.14 KND96061.1 - 0.27 10.7 2.4 1.1 8.7 1.6 2.1 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M DUF21 PF01595.15 KND96061.1 - 1.4 8.2 14.2 0.043 13.1 2.7 3.0 1 1 1 2 2 2 0 Domain of unknown function DUF21 Paf1 PF03985.8 KND96062.1 - 6.6e-114 381.0 20.6 7.4e-114 380.8 14.3 1.0 1 0 0 1 1 1 1 Paf1 DUF1824 PF08854.5 KND96062.1 - 0.018 14.6 0.2 0.041 13.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) DUF544 PF04424.8 KND96063.1 - 1.7e-08 34.2 0.1 3.9e-08 33.1 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF544) SQS_PSY PF00494.14 KND96064.1 - 5e-42 144.0 0.0 6.2e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Gtr1_RagA PF04670.7 KND96066.1 - 6.5e-81 270.8 4.0 8.2e-81 270.5 2.8 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 KND96066.1 - 1.5e-05 24.3 0.2 3.2e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KND96066.1 - 7.2e-05 22.2 0.2 0.00013 21.3 0.1 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KND96066.1 - 0.00057 20.3 0.1 0.0013 19.1 0.1 1.6 1 0 0 1 1 1 1 Miro-like protein ICMT PF04140.9 KND96067.1 - 3.9e-22 78.2 0.4 3.9e-22 78.2 0.2 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KND96067.1 - 4.2e-14 52.5 2.0 4.2e-14 52.5 1.4 2.1 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 KND96067.1 - 1.5e-06 27.6 1.6 2.5e-06 26.9 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) FA_desaturase PF00487.19 KND96068.1 - 2.8e-21 76.1 31.8 3.7e-21 75.7 22.0 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DnaJ PF00226.26 KND96070.1 - 2.4e-24 84.8 2.0 2.6e-23 81.5 0.1 2.8 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 KND96070.1 - 2.2e-12 46.7 13.6 1.7e-11 43.8 1.7 2.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KND96070.1 - 1.2e-10 41.2 6.5 6.3e-09 35.7 0.8 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KND96070.1 - 3.6e-06 26.9 10.7 0.0018 18.3 0.2 3.5 4 0 0 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KND96070.1 - 2.8e-05 24.1 5.0 0.094 13.0 0.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND96070.1 - 0.00029 20.9 1.5 0.91 10.0 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KND96070.1 - 0.014 15.6 1.0 0.52 10.6 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 KND96070.1 - 0.022 14.6 2.1 5.8 6.9 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger FPN1 PF06963.7 KND96070.1 - 0.58 8.4 2.1 0.55 8.5 0.5 1.6 2 0 0 2 2 2 0 Ferroportin1 (FPN1) DUF2387 PF09526.5 KND96070.1 - 5.7 6.9 12.6 0.67 9.9 1.0 4.0 3 1 1 4 4 4 0 Probable metal-binding protein (DUF2387) DUF883 PF05957.8 KND96072.1 - 0.57 10.6 28.0 0.21 11.9 0.8 5.1 2 1 5 7 7 7 0 Bacterial protein of unknown function (DUF883) tRNA-synt_2b PF00587.20 KND96073.1 - 1.3e-34 119.2 0.0 1.9e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KND96073.1 - 0.0085 16.0 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain DUF3039 PF11238.3 KND96073.1 - 0.068 12.6 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) tRNA-synt_2 PF00152.15 KND96073.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) Sec61_beta PF03911.11 KND96075.1 - 2.6e-17 62.3 1.5 3.1e-17 62.0 1.0 1.1 1 0 0 1 1 1 1 Sec61beta family RRM_6 PF14259.1 KND96078.1 - 3.1e-07 30.2 0.0 6.7e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KND96078.1 - 1.3e-06 27.9 0.0 3.2e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND96078.1 - 7.4e-05 22.5 0.1 0.00024 20.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PP2C PF00481.16 KND96079.1 - 1.4e-74 250.7 0.0 2.6e-74 249.8 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KND96079.1 - 0.0037 16.6 0.0 0.009 15.4 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C Dpoe2NT PF12213.3 KND96079.1 - 0.027 14.3 1.6 0.028 14.3 0.0 1.8 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal MOZ_SAS PF01853.13 KND96081.1 - 5e-74 247.6 0.4 7.9e-74 246.9 0.3 1.2 1 0 0 1 1 1 1 MOZ/SAS family KIX PF02172.11 KND96081.1 - 0.07 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 KIX domain zf-C2H2 PF00096.21 KND96081.1 - 0.73 10.2 2.7 1.5 9.3 1.9 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type TatD_DNase PF01026.16 KND96082.1 - 5.3e-41 140.5 0.0 3.5e-40 137.8 0.0 1.9 1 1 0 1 1 1 1 TatD related DNase DnaJ PF00226.26 KND96083.1 - 1.1e-09 37.8 0.3 1.1e-09 37.8 0.2 2.2 2 2 0 2 2 2 1 DnaJ domain DUF826 PF05696.6 KND96083.1 - 0.18 11.9 6.4 0.34 11.0 0.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF826) ATP-synt_ab PF00006.20 KND96084.1 - 1.6e-63 214.1 0.0 2.2e-63 213.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KND96084.1 - 1.8e-27 96.0 0.6 2.9e-27 95.4 0.4 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain KaiC PF06745.8 KND96084.1 - 0.0034 16.5 1.1 0.0038 16.3 0.2 1.6 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.1 KND96084.1 - 0.0038 16.6 0.1 0.014 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KND96084.1 - 0.0099 15.5 0.2 0.55 9.9 0.0 3.0 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KND96084.1 - 0.016 15.1 0.3 0.15 11.9 0.0 2.3 1 1 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.17 KND96084.1 - 0.018 13.9 0.3 0.39 9.5 0.1 2.1 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 KND96084.1 - 0.022 14.4 0.1 0.058 13.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DUF463 PF04317.7 KND96084.1 - 0.035 12.6 0.0 0.052 12.1 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 DUF258 PF03193.11 KND96084.1 - 0.037 13.1 0.1 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 KND96084.1 - 0.072 12.7 0.0 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 KND96084.1 - 0.075 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATP-synt_ab_N PF02874.18 KND96084.1 - 0.13 12.4 2.3 0.17 12.0 0.5 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, beta-barrel domain AAA_22 PF13401.1 KND96084.1 - 0.13 12.3 0.0 0.42 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain JmjC PF02373.17 KND96086.1 - 1.6e-39 134.6 0.2 3.8e-39 133.4 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 KND96086.1 - 8e-12 44.6 5.3 8e-12 44.6 3.7 2.5 2 0 0 2 2 2 1 PHD-finger JmjN PF02375.12 KND96086.1 - 4.5e-10 38.8 0.0 1e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 jmjN domain PHD_2 PF13831.1 KND96086.1 - 0.001 18.3 1.2 0.001 18.3 0.8 3.2 3 0 0 3 3 3 1 PHD-finger Prok-RING_1 PF14446.1 KND96086.1 - 0.0063 16.2 1.2 0.0063 16.2 0.9 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 IGR PF09597.5 KND96086.1 - 0.041 13.7 0.1 2.4 8.1 0.0 3.2 3 0 0 3 3 3 0 IGR protein motif P5CR_dimer PF14748.1 KND96087.1 - 5.9e-34 116.3 3.1 1.2e-33 115.2 2.2 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KND96087.1 - 8.6e-09 35.7 0.2 2.4e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KND96087.1 - 0.0001 22.1 0.1 0.00018 21.2 0.1 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 KND96087.1 - 0.0017 17.7 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Ribonuc_red_lgN PF00317.16 KND96089.1 - 0.016 14.9 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain ComZ PF10815.3 KND96089.1 - 0.071 12.8 0.1 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 ComZ DUF964 PF06133.6 KND96089.1 - 0.095 12.7 0.3 0.5 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF964) Nexin_C PF08628.7 KND96089.1 - 0.099 12.7 0.1 0.66 10.0 0.1 1.9 1 1 1 2 2 2 0 Sorting nexin C terminal Helicase_C PF00271.26 KND96091.1 - 3.7e-23 81.1 0.0 1.7e-22 79.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KND96091.1 - 3.2e-17 62.5 0.0 7.4e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase CMS1 PF14617.1 KND96091.1 - 0.034 13.2 0.1 0.076 12.0 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit MUG113 PF13455.1 KND96092.1 - 1.3e-09 38.3 5.3 3.8e-05 24.0 0.4 3.3 2 1 1 3 3 3 2 Meiotically up-regulated gene 113 T5orf172 PF10544.4 KND96092.1 - 3.5e-07 30.5 2.6 7.5e-05 23.0 1.8 3.1 1 1 0 1 1 1 1 T5orf172 domain Cys_Met_Meta_PP PF01053.15 KND96093.1 - 1.9e-145 483.9 0.0 2.2e-145 483.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KND96093.1 - 5.3e-10 38.8 0.0 1.3e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KND96093.1 - 4.4e-09 35.5 0.1 8e-09 34.7 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KND96093.1 - 1.3e-08 34.2 0.0 2.4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.6 KND96093.1 - 3e-05 22.5 0.2 4.7e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 KND96093.1 - 0.00012 20.8 0.0 0.00019 20.2 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 KND96093.1 - 0.0007 18.8 0.0 0.0011 18.1 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Phg_2220_C PF09524.5 KND96093.1 - 0.016 15.2 0.2 0.17 11.8 0.0 2.7 2 1 1 3 3 3 0 Conserved phage C-terminus (Phg_2220_C) Radical_SAM PF04055.16 KND96093.1 - 0.056 13.6 0.0 1 9.4 0.0 2.4 2 0 0 2 2 2 0 Radical SAM superfamily SUR7 PF06687.7 KND96095.1 - 1.1e-07 31.6 1.2 1.8e-07 30.9 0.9 1.3 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 KND96095.1 - 0.011 15.6 4.5 0.02 14.7 3.1 1.3 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 RNR_inhib PF08591.5 KND96096.1 - 1.2e-11 45.4 0.2 4.1e-11 43.6 0.1 1.9 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor Aminotran_3 PF00202.16 KND96098.1 - 1.2e-107 359.7 0.0 1.4e-107 359.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 KND96098.1 - 0.00095 18.3 0.0 0.0025 16.9 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KND96098.1 - 0.0013 17.8 0.0 0.0022 17.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Pea-VEAacid PF08111.6 KND96098.1 - 0.13 12.4 1.6 0.32 11.1 1.1 1.7 1 0 0 1 1 1 0 Pea-VEAacid family Nha1_C PF08619.5 KND96099.1 - 4.3e-73 247.0 26.1 5e-73 246.8 18.1 1.0 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 KND96099.1 - 2.2e-69 233.8 20.6 2.6e-69 233.6 14.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 KND96099.1 - 0.14 12.1 0.2 0.45 10.5 0.1 1.8 1 0 0 1 1 1 0 YrhC-like protein ChaC PF04752.7 KND96101.1 - 2.8e-50 170.7 0.0 8.9e-50 169.1 0.0 1.7 1 1 0 1 1 1 1 ChaC-like protein TFR_dimer PF04253.10 KND96102.1 - 5.3e-11 42.1 0.0 1e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 KND96102.1 - 9.4e-07 28.4 0.0 2.9e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 PA domain Peptidase_M28 PF04389.12 KND96102.1 - 2e-06 27.6 0.0 4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Patatin PF01734.17 KND96102.1 - 0.042 13.7 0.3 0.42 10.5 0.2 2.3 1 1 0 1 1 1 0 Patatin-like phospholipase zf-RING_5 PF14634.1 KND96105.1 - 5.5e-07 29.2 2.9 1.1e-06 28.2 2.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KND96105.1 - 1.2e-06 28.3 6.2 2.3e-06 27.4 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KND96105.1 - 2.5e-06 27.0 5.2 4.7e-06 26.1 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KND96105.1 - 7e-06 25.6 3.7 1.1e-05 24.9 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KND96105.1 - 7.2e-06 25.7 4.2 1.3e-05 24.9 2.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KND96105.1 - 0.001 18.9 3.3 0.001 18.9 2.3 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KND96105.1 - 0.0022 17.6 3.8 0.0055 16.4 2.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.1 KND96105.1 - 0.26 10.8 8.0 15 5.1 0.6 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 BRF1 PF07741.8 KND96105.1 - 5.4 7.3 12.8 6 7.1 3.0 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain adh_short PF00106.20 KND96107.1 - 1.8e-20 73.5 0.1 2.6e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND96107.1 - 7.8e-08 32.1 0.4 1.8e-07 30.9 0.3 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KND96107.1 - 1.3e-05 25.0 0.1 1.8e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KND96107.1 - 0.0062 15.7 0.8 0.0087 15.2 0.6 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3Beta_HSD PF01073.14 KND96107.1 - 0.0077 14.9 0.0 0.014 14.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KND96107.1 - 0.034 13.5 0.1 0.22 10.9 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4520 PF15016.1 KND96107.1 - 0.15 11.6 0.2 0.61 9.6 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4520) Diphthamide_syn PF01866.12 KND96108.1 - 1.5e-41 142.6 0.0 9.1e-41 140.0 0.0 2.0 1 1 0 1 1 1 1 Putative diphthamide synthesis protein Nucleoside_tran PF01733.13 KND96111.1 - 8.9e-51 172.8 12.6 3.8e-50 170.8 8.7 1.8 1 1 0 1 1 1 1 Nucleoside transporter Ion_trans_2 PF07885.11 KND96113.1 - 6.3e-27 93.1 30.1 1.4e-15 56.7 5.5 4.4 4 1 1 5 5 5 2 Ion channel DUF1109 PF06532.6 KND96113.1 - 0.00078 18.9 7.5 0.039 13.3 1.1 3.3 2 1 0 3 3 3 2 Protein of unknown function (DUF1109) Ribosomal_S17 PF00366.15 KND96115.1 - 2e-08 34.1 2.5 2e-08 34.1 1.7 1.9 1 1 1 2 2 2 1 Ribosomal protein S17 Cwf_Cwc_15 PF04889.7 KND96115.1 - 0.41 10.3 12.9 0.5 10.0 9.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_Rpb1_5 PF04998.12 KND96115.1 - 6.9 5.8 8.1 8.9 5.4 5.6 1.3 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF1492 PF07374.6 KND96115.1 - 9.1 6.4 8.8 1.2 9.2 1.7 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1492) TPR_11 PF13414.1 KND96117.1 - 1e-06 28.2 1.4 0.0046 16.5 0.0 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KND96117.1 - 4.1e-06 26.2 3.5 7.5e-05 22.3 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KND96117.1 - 4.2e-06 26.1 4.1 5.3e-05 22.6 0.3 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KND96117.1 - 0.0069 16.2 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 KND96117.1 - 0.067 13.0 0.7 0.72 9.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KND96117.1 - 0.11 12.3 0.5 4 7.4 0.0 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 KND96117.1 - 0.12 13.0 1.4 0.29 11.8 0.1 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat SNF2_N PF00176.18 KND96118.1 - 1.8e-68 230.5 1.7 2.6e-68 230.0 1.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KND96118.1 - 3.9e-13 49.0 0.0 1e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 KND96118.1 - 1.2e-06 28.0 3.9 2.8e-06 26.9 2.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KND96118.1 - 1.9e-05 24.3 5.9 3.7e-05 23.4 4.1 1.5 1 0 0 1 1 1 1 Ring finger domain ResIII PF04851.10 KND96118.1 - 2.7e-05 24.1 0.0 9.6e-05 22.2 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.1 KND96118.1 - 0.00012 21.9 6.0 0.00033 20.6 4.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND96118.1 - 0.00022 20.8 3.9 0.0005 19.7 2.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KND96118.1 - 0.0004 19.9 4.4 0.001 18.6 3.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 KND96118.1 - 0.0094 15.4 0.1 0.1 12.1 0.1 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_4 PF15227.1 KND96118.1 - 0.11 12.4 6.3 0.36 10.7 4.5 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KND96118.1 - 0.11 12.2 1.8 0.3 10.8 1.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger FYVE PF01363.16 KND96118.1 - 0.46 10.4 1.5 1.1 9.2 1.1 1.6 1 0 0 1 1 1 0 FYVE zinc finger Prok-RING_4 PF14447.1 KND96118.1 - 0.66 9.5 5.6 4.6 6.8 3.9 2.3 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KND96118.1 - 1.2 8.7 3.9 2.8 7.6 2.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Dor1 PF04124.7 KND96119.1 - 9.2e-19 67.0 11.1 2.3e-17 62.4 7.7 2.5 1 1 0 1 1 1 1 Dor1-like family Methyltrans_Mon PF14314.1 KND96119.1 - 0.00027 18.9 0.1 0.00038 18.4 0.0 1.1 1 0 0 1 1 1 1 Virus-capping methyltransferase vATP-synt_AC39 PF01992.11 KND96120.1 - 1.5e-85 287.3 0.0 1.7e-85 287.1 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DUF4372 PF14294.1 KND96120.1 - 0.094 12.5 0.1 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4372) Rad1 PF02144.11 KND96121.1 - 5.9e-53 179.4 0.7 7.1e-53 179.1 0.5 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 DUF2413 PF10310.4 KND96122.1 - 0.54 9.0 11.4 0.69 8.6 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) AA_permease_2 PF13520.1 KND96123.1 - 4.1e-55 187.0 33.3 5e-52 176.8 18.0 1.9 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.16 KND96123.1 - 1e-07 30.6 27.9 1e-07 30.6 19.4 1.5 2 0 0 2 2 2 1 Amino acid permease SurE PF01975.12 KND96124.1 - 1.2e-13 50.7 0.0 1.2e-05 24.6 0.0 3.2 3 0 0 3 3 3 3 Survival protein SurE Rnk_N PF14760.1 KND96124.1 - 0.56 10.3 5.4 9.4 6.3 0.1 3.3 3 0 0 3 3 3 0 Rnk N-terminus adh_short PF00106.20 KND96125.1 - 1.2e-21 77.3 0.0 1.8e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND96125.1 - 1.1e-12 48.2 0.0 1.4e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND96125.1 - 8.6e-07 28.7 0.0 1.9e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KND96125.1 - 0.0022 18.0 0.0 0.0037 17.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 KND96125.1 - 0.035 13.2 0.0 0.91 8.5 0.0 2.5 2 1 0 2 2 2 0 Fungal family of unknown function (DUF1776) DUF2370 PF10176.4 KND96126.1 - 9.8e-74 247.6 0.0 1.4e-73 247.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Mito_carr PF00153.22 KND96128.1 - 6.2e-24 83.5 0.2 7e-24 83.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein DUF787 PF05619.6 KND96128.1 - 0.043 12.4 0.0 0.052 12.2 0.0 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF787) TFIIE_alpha PF02002.12 KND96129.1 - 5.3e-17 61.2 0.5 5.3e-17 61.2 0.3 1.8 2 0 0 2 2 2 1 TFIIE alpha subunit Rab_eff_C PF04698.7 KND96129.1 - 0.00075 17.7 2.4 0.001 17.3 1.6 1.1 1 0 0 1 1 1 1 Rab effector MyRIP/melanophilin C-terminus TF_Zn_Ribbon PF08271.7 KND96129.1 - 0.0025 17.0 0.6 0.01 15.1 0.4 2.0 1 1 0 1 1 1 1 TFIIB zinc-binding zf-TFIIB PF13453.1 KND96129.1 - 0.034 13.3 0.1 0.073 12.2 0.1 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger DZR PF12773.2 KND96129.1 - 0.069 12.9 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-FPG_IleRS PF06827.9 KND96129.1 - 0.12 12.0 2.2 0.66 9.6 1.5 2.2 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS Fork_head PF00250.13 KND96133.1 - 1.6e-27 95.3 0.8 2.6e-27 94.6 0.5 1.3 1 0 0 1 1 1 1 Fork head domain G10 PF01125.12 KND96135.1 - 3.6e-56 188.7 8.6 4e-56 188.5 5.9 1.0 1 0 0 1 1 1 1 G10 protein DUF4315 PF14193.1 KND96135.1 - 0.96 9.4 4.4 1.8 8.5 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) Methyltransf_28 PF02636.12 KND96136.1 - 2.4e-35 122.1 0.0 4.7e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Mg_trans_NIPA PF05653.9 KND96138.1 - 3.5e-112 374.2 17.0 4.1e-112 374.0 11.8 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KND96138.1 - 1.3e-06 28.6 3.8 1.3e-06 28.6 2.7 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KND96138.1 - 0.00026 21.0 8.2 0.00026 21.0 5.7 3.5 2 1 1 3 3 3 1 EamA-like transporter family DUF2937 PF11157.3 KND96138.1 - 0.18 11.1 1.5 0.26 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Pkinase PF00069.20 KND96139.1 - 7.2e-20 71.2 0.0 1.4e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 KND96139.1 - 3.7e-08 32.9 6.7 6.8e-05 22.5 0.0 4.6 6 0 0 6 6 6 2 WD domain, G-beta repeat Pkinase_Tyr PF07714.12 KND96139.1 - 8.6e-06 25.0 0.0 1.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.17 KND96139.1 - 0.0001 22.0 0.1 0.083 13.0 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat APH PF01636.18 KND96139.1 - 0.0098 15.6 0.1 0.019 14.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Apc4_WD40 PF12894.2 KND96139.1 - 0.028 13.8 0.0 11 5.5 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 PF13646.1 KND96139.1 - 0.05 13.8 0.0 0.24 11.6 0.0 2.3 1 1 0 1 1 1 0 HEAT repeats Tfb4 PF03850.9 KND96141.1 - 1.1e-95 320.0 0.9 1.3e-95 319.8 0.7 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 KND96141.1 - 0.00088 19.4 0.4 0.0014 18.8 0.2 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain ZapA PF05164.8 KND96141.1 - 0.064 13.2 0.1 0.62 10.0 0.1 2.2 2 0 0 2 2 2 0 Cell division protein ZapA SIP1 PF04938.7 KND96145.1 - 1.7e-08 34.1 0.6 5.8e-08 32.3 0.4 1.8 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) FliG_N PF14842.1 KND96145.1 - 0.14 12.2 3.7 0.14 12.3 0.6 2.3 2 2 0 2 2 2 0 FliG N-terminal domain UPF0139 PF03669.8 KND96146.1 - 0.0053 16.2 0.2 0.0078 15.7 0.2 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0139) WD40 PF00400.27 KND96147.1 - 1.1e-16 60.0 13.4 0.0091 15.8 0.1 7.5 8 0 0 8 8 8 4 WD domain, G-beta repeat LisH PF08513.6 KND96147.1 - 1.5e-09 37.2 1.5 2.6e-09 36.4 0.3 2.0 2 0 0 2 2 2 1 LisH eIF2A PF08662.6 KND96147.1 - 7.9e-05 22.4 0.3 0.0019 17.9 0.0 3.0 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Vps51 PF08700.6 KND96148.1 - 0.0063 16.3 3.4 0.025 14.3 2.3 2.2 1 0 0 1 1 1 1 Vps51/Vps67 DUF1799 PF08809.6 KND96148.1 - 0.12 12.2 0.2 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 Phage related hypothetical protein (DUF1799) MFS_1 PF07690.11 KND96149.1 - 7.8e-45 153.1 17.0 7.8e-45 153.1 11.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 KND96149.1 - 0.15 10.0 7.2 0.019 13.0 0.8 2.4 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Tmemb_170 PF10190.4 KND96151.1 - 0.042 13.9 1.8 0.059 13.4 1.1 1.4 2 0 0 2 2 2 0 Putative transmembrane protein 170 GAT PF03127.9 KND96152.1 - 0.0016 18.4 0.4 0.0017 18.3 0.3 1.0 1 0 0 1 1 1 1 GAT domain Acyltransferase PF01553.16 KND96154.1 - 8.6e-23 80.2 0.0 2e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Fig1 PF12351.3 KND96156.1 - 2.8e-37 128.3 9.3 3.5e-37 128.0 6.5 1.0 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 KND96156.1 - 0.037 13.5 7.6 0.051 13.1 5.3 1.1 1 0 0 1 1 1 0 SUR7/PalI family 2TM PF13239.1 KND96156.1 - 6.9 6.8 5.6 8.1 6.5 1.7 2.2 1 1 1 2 2 2 0 2TM domain FAT PF02259.18 KND96157.1 - 2.2e-76 257.1 4.0 7.2e-76 255.4 2.8 2.0 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 KND96157.1 - 1.3e-29 103.3 0.3 4.4e-29 101.6 0.1 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KND96157.1 - 4e-08 32.5 0.1 1.2e-07 31.0 0.1 1.8 1 0 0 1 1 1 1 FATC domain PGP_phosphatase PF09419.5 KND96158.1 - 3.4e-70 234.7 0.0 4.1e-70 234.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 KND96158.1 - 4.2e-07 29.5 0.0 7.8e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like zf-C3HC4_3 PF13920.1 KND96159.1 - 0.0026 17.4 11.5 0.0026 17.4 8.0 3.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-DNL PF05180.7 KND96160.1 - 2.5e-31 107.1 0.5 3.6e-31 106.6 0.3 1.2 1 0 0 1 1 1 1 DNL zinc finger zinc_ribbon_4 PF13717.1 KND96160.1 - 0.028 14.1 2.8 0.63 9.7 0.0 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KND96160.1 - 0.032 13.8 2.5 0.75 9.4 0.0 2.7 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 KND96160.1 - 0.037 13.9 1.5 0.096 12.6 0.3 2.1 2 0 0 2 2 2 0 Zinc ribbon domain TFIIS_C PF01096.13 KND96160.1 - 0.038 13.6 1.4 5.8 6.6 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) CGGC PF08821.6 KND96160.1 - 0.082 12.9 0.4 0.12 12.4 0.3 1.4 1 1 0 1 1 1 0 CGGC domain ATP11 PF06644.6 KND96161.1 - 5.7e-90 301.4 9.8 6.5e-90 301.2 6.8 1.0 1 0 0 1 1 1 1 ATP11 protein zf-C4H2 PF10146.4 KND96161.1 - 0.022 14.7 5.6 0.042 13.8 3.8 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein DUF1479 PF07350.7 KND96161.1 - 0.041 12.3 4.4 0.055 11.9 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Peptidase_S49_N PF08496.5 KND96161.1 - 2.6 7.7 8.3 4.2 7.1 5.7 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3987 PF13148.1 KND96161.1 - 5 5.5 9.3 7.4 5.0 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Mre11_DNA_bind PF04152.9 KND96162.1 - 3e-47 160.7 0.9 3e-47 160.7 0.6 1.8 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 KND96162.1 - 1.3e-18 67.1 1.0 2.1e-18 66.4 0.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MCPVI PF02993.9 KND96162.1 - 0.66 10.0 5.6 1.1 9.4 3.9 1.3 1 0 0 1 1 1 0 Minor capsid protein VI HGTP_anticodon2 PF12745.2 KND96163.1 - 2e-81 273.1 8.4 2e-81 273.1 5.8 3.2 4 0 0 4 4 4 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 KND96163.1 - 7.3e-58 195.7 0.1 7.9e-40 136.6 0.0 4.0 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KND96163.1 - 1.2e-29 103.1 0.0 1.2e-19 70.3 0.0 3.4 3 0 0 3 3 3 2 Protein tyrosine kinase RWD PF05773.17 KND96163.1 - 2.3e-17 62.8 0.5 7e-17 61.3 0.3 1.9 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 KND96163.1 - 4.3e-08 32.5 0.2 1.8e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 Histidyl-tRNA synthetase Kinase-like PF14531.1 KND96163.1 - 1.6e-05 23.9 0.0 3.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KND96163.1 - 0.068 12.8 0.2 0.4 10.3 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND96164.1 - 2e-42 145.1 0.2 4.2e-41 140.8 0.0 2.3 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 KND96164.1 - 0.00093 18.9 0.0 0.0071 16.1 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family PAP2 PF01569.16 KND96165.1 - 4.3e-21 74.9 4.4 4.3e-21 74.9 3.0 1.7 2 0 0 2 2 2 1 PAP2 superfamily EcsB PF05975.7 KND96165.1 - 0.41 9.0 4.5 0.35 9.2 1.0 1.9 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB NfeD PF01957.13 KND96165.1 - 0.48 10.5 5.3 2.4 8.2 0.2 2.3 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding PAP2_C PF14360.1 KND96165.1 - 1.5 9.1 6.0 0.35 11.1 0.5 2.3 2 0 0 2 2 2 0 PAP2 superfamily C-terminal PX PF00787.19 KND96167.1 - 5.2e-09 35.9 0.0 1.4e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 PX domain PX PF00787.19 KND96168.1 - 8e-07 28.8 0.1 5.5e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 PX domain Sld5 PF05916.6 KND96168.1 - 0.091 13.0 1.6 0.17 12.1 0.3 2.0 2 1 0 2 2 2 0 GINS complex protein Yae1_N PF09811.4 KND96169.1 - 1.3e-11 43.8 0.9 1.9e-11 43.3 0.6 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal BTB_2 PF02214.17 KND96170.1 - 0.0088 16.2 0.0 0.026 14.7 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Corona_nucleoca PF00937.13 KND96170.1 - 0.12 11.2 0.7 0.17 10.8 0.5 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein AAA PF00004.24 KND96172.1 - 6.8e-16 58.6 0.0 2.2e-15 57.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KND96172.1 - 4e-13 49.3 0.1 1.3e-11 44.4 0.0 2.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 KND96172.1 - 2.3e-12 46.7 0.7 5.1e-12 45.6 0.3 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 KND96172.1 - 7.1e-11 41.4 0.6 2.8e-07 29.6 0.0 2.3 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KND96172.1 - 4.4e-07 30.0 0.4 5.1e-06 26.6 0.0 2.7 3 1 0 3 3 1 1 AAA domain RuvB_N PF05496.7 KND96172.1 - 1.9e-05 23.8 0.0 7.6e-05 21.8 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 KND96172.1 - 3.7e-05 23.4 0.0 4.7e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND96172.1 - 3.7e-05 23.3 0.1 0.00018 21.1 0.1 2.1 1 1 1 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 KND96172.1 - 8.5e-05 23.3 0.0 0.00037 21.3 0.0 2.0 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KND96172.1 - 9e-05 22.5 1.1 0.0019 18.2 0.0 2.9 2 2 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 KND96172.1 - 0.00037 20.3 0.0 0.00076 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 KND96172.1 - 0.00039 19.4 0.0 0.00097 18.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 KND96172.1 - 0.00049 19.3 0.0 0.02 14.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KND96172.1 - 0.00062 19.5 0.0 0.0025 17.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DNA_pol3_gamma3 PF12169.3 KND96172.1 - 0.00067 19.4 0.1 0.0016 18.1 0.1 1.8 1 0 0 1 1 1 1 DNA polymerase III subunits gamma and tau domain III AAA_10 PF12846.2 KND96172.1 - 0.0021 17.5 0.0 0.03 13.7 0.0 2.1 1 1 1 2 2 2 1 AAA-like domain AAA_30 PF13604.1 KND96172.1 - 0.0028 17.2 0.0 0.016 14.7 0.0 2.3 2 2 1 3 3 3 1 AAA domain AAA_24 PF13479.1 KND96172.1 - 0.0038 16.8 0.5 0.0093 15.5 0.4 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KND96172.1 - 0.0068 15.8 0.1 0.022 14.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KND96172.1 - 0.0068 15.4 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 KND96172.1 - 0.0072 15.8 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_3 PF07726.6 KND96172.1 - 0.015 14.8 0.0 0.12 11.9 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KND96172.1 - 0.033 13.8 0.0 0.99 9.0 0.0 2.3 1 1 0 2 2 2 0 Archaeal ATPase ResIII PF04851.10 KND96172.1 - 0.034 13.9 0.0 0.14 11.9 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.11 KND96172.1 - 0.038 13.2 0.1 2.3 7.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_23 PF13476.1 KND96172.1 - 0.042 14.1 0.0 0.072 13.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KND96172.1 - 0.043 13.9 0.0 0.13 12.4 0.0 2.0 2 1 0 2 2 1 0 RNA helicase SNF2_N PF00176.18 KND96172.1 - 0.052 12.3 0.0 1.4 7.6 0.0 2.2 1 1 0 2 2 2 0 SNF2 family N-terminal domain AAA_18 PF13238.1 KND96172.1 - 0.053 13.8 0.1 0.21 11.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KND96172.1 - 0.059 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KND96172.1 - 0.089 13.0 0.0 0.92 9.8 0.0 2.3 1 1 1 2 2 2 0 ABC transporter Asp PF00026.18 KND96177.1 - 1.5e-54 185.3 7.4 1.9e-54 185.0 5.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 KND96177.1 - 0.011 15.3 0.0 0.075 12.5 0.0 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Stap_Strp_tox_C PF02876.12 KND96177.1 - 0.02 15.0 0.0 0.059 13.5 0.0 1.7 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain zf-SNAP50_C PF12251.3 KND96178.1 - 0.03 13.7 0.2 0.29 10.5 0.1 2.0 2 0 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal DSPc PF00782.15 KND96179.1 - 6.9e-24 83.9 1.8 1.1e-18 67.1 0.1 3.4 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KND96179.1 - 2.6e-06 26.9 0.0 5.6e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF3453 PF11935.3 KND96181.1 - 5.3e-50 170.0 0.9 1.1e-49 169.0 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Sds3 PF08598.6 KND96181.1 - 0.17 11.4 4.2 0.96 8.9 2.3 2.3 2 1 1 3 3 3 0 Sds3-like Coiled-coil_56 PF09813.4 KND96183.1 - 0.076 13.0 0.0 0.08 12.9 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 PALP PF00291.20 KND96188.1 - 6.8e-63 212.7 0.0 7.7e-63 212.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Atx10homo_assoc PF09759.4 KND96190.1 - 9.2e-30 102.3 1.5 1.6e-29 101.6 0.4 1.9 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Thr_synth_N PF14821.1 KND96191.1 - 5.3e-28 96.8 0.0 1.5e-27 95.4 0.0 1.9 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 KND96191.1 - 7.8e-21 74.5 0.0 1.3e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Mmp37 PF09139.6 KND96192.1 - 2e-94 316.3 3.0 2.4e-94 316.0 2.1 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 SAP30_Sin3_bdg PF13867.1 KND96193.1 - 4.2e-14 52.1 1.0 2.9e-12 46.2 0.0 2.3 1 1 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 WD40 PF00400.27 KND96194.1 - 1e-36 123.4 8.1 8.1e-09 35.0 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KND96194.1 - 3e-05 23.8 0.1 0.017 14.8 0.1 3.7 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KND96194.1 - 0.00047 19.7 2.3 3.9 7.2 0.1 4.3 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat CUE PF02845.11 KND96195.1 - 2.3e-05 23.7 0.0 4.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 CUE domain Hex_IIIa PF02455.11 KND96195.1 - 0.021 13.5 0.3 0.025 13.2 0.2 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Sugar_tr PF00083.19 KND96197.1 - 5.1e-90 302.2 16.0 6e-90 301.9 11.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND96197.1 - 5.7e-30 104.2 24.9 7.4e-21 74.2 1.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KND96197.1 - 0.00016 20.1 21.5 0.0014 17.0 5.0 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein SdpI PF13630.1 KND96197.1 - 0.67 9.7 11.7 4.6 7.0 0.8 4.0 3 0 0 3 3 3 0 SdpI/YhfL protein family SNARE PF05739.14 KND96198.1 - 0.001 18.7 1.5 0.001 18.7 1.1 3.5 4 0 0 4 4 4 1 SNARE domain V-SNARE_C PF12352.3 KND96198.1 - 0.028 14.4 0.5 0.13 12.3 0.3 2.2 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Lge1 PF11488.3 KND96198.1 - 3.1 8.0 7.8 0.68 10.1 2.0 2.5 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Toxin_38 PF14866.1 KND96199.1 - 0.041 13.9 0.3 0.059 13.4 0.2 1.3 1 0 0 1 1 1 0 Potassium channel toxin zf-CSL PF05207.8 KND96199.1 - 0.1 12.1 0.2 0.23 11.0 0.1 1.7 1 1 0 1 1 1 0 CSL zinc finger MFS_1 PF07690.11 KND96200.1 - 4.7e-25 88.0 10.9 4.7e-25 88.0 7.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 KND96200.1 - 0.7 9.9 7.1 3 7.9 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Ribosomal_L7Ae PF01248.21 KND96201.1 - 2.2e-27 94.3 0.2 3.3e-27 93.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CPDase PF07823.6 KND96202.1 - 0.017 14.6 0.1 0.023 14.1 0.1 1.2 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein Adaptin_N PF01602.15 KND96203.1 - 3.6e-96 322.5 11.6 4.9e-96 322.1 8.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 KND96203.1 - 1.4e-61 205.8 0.0 3.7e-61 204.5 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 KND96203.1 - 7.6e-53 177.9 1.1 7.6e-53 177.9 0.7 2.0 2 0 0 2 2 2 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 KND96203.1 - 1.6e-10 41.0 2.2 4.2e-05 23.7 0.0 4.3 3 1 2 5 5 5 2 HEAT repeats Cnd1 PF12717.2 KND96203.1 - 2.8e-06 27.3 12.0 0.015 15.1 0.2 4.6 3 2 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 FANCI_S2 PF14676.1 KND96203.1 - 0.00017 21.5 2.2 0.003 17.4 0.4 3.1 3 0 0 3 3 3 1 FANCI solenoid 2 HEAT PF02985.17 KND96203.1 - 0.00036 20.3 0.5 0.12 12.4 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 KND96203.1 - 0.013 15.9 1.6 2.1 8.9 0.0 4.9 6 1 1 7 7 7 0 HEAT-like repeat AP4E_app_platf PF14807.1 KND96203.1 - 0.021 15.0 0.1 0.13 12.5 0.0 2.5 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform IZUMO PF15005.1 KND96203.1 - 0.088 12.8 1.5 0.22 11.5 0.2 2.4 2 0 0 2 2 2 0 Izumo sperm-egg fusion Peptidase_M24 PF00557.19 KND96205.1 - 2.5e-19 69.6 0.0 5.3e-19 68.6 0.0 1.5 2 0 0 2 2 2 1 Metallopeptidase family M24 PHD PF00628.24 KND96206.1 - 3.2e-13 49.1 23.8 6.5e-09 35.3 8.0 2.4 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.17 KND96206.1 - 0.28 10.9 17.8 0.078 12.7 1.1 2.7 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.1 KND96206.1 - 0.38 10.9 10.1 0.38 10.9 2.7 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KND96206.1 - 2.5 8.1 8.7 7 6.7 2.6 2.4 2 0 0 2 2 2 0 PHD-zinc-finger like domain L51_S25_CI-B8 PF05047.11 KND96207.1 - 2.5e-07 30.3 0.0 3.7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ArgJ PF01960.13 KND96208.1 - 2.4e-148 493.6 6.1 2.8e-148 493.4 4.2 1.0 1 0 0 1 1 1 1 ArgJ family adh_short PF00106.20 KND96210.1 - 2.9e-26 92.3 0.0 5.1e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND96210.1 - 2.2e-07 30.9 0.0 3.1e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND96210.1 - 1.7e-06 27.8 0.1 3.1e-05 23.7 0.1 2.2 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KND96210.1 - 0.002 18.1 0.0 0.0067 16.4 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding Thi4 PF01946.12 KND96210.1 - 0.09 11.8 0.5 0.15 11.1 0.3 1.2 1 0 0 1 1 1 0 Thi4 family DUF1776 PF08643.5 KND96210.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Hydrolase_6 PF13344.1 KND96210.1 - 0.14 12.0 0.0 1.9 8.4 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF1762 PF08574.5 KND96211.1 - 7e-20 71.2 11.7 7e-20 71.2 8.1 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1762) RNA_pol PF00940.14 KND96212.1 - 6.1e-129 430.0 2.3 9.7e-129 429.3 1.6 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 KND96212.1 - 7.3e-22 78.0 0.0 2.5e-18 66.3 0.0 2.6 1 1 1 2 2 2 2 DNA-directed RNA polymerase N-terminal TRAPP PF04051.11 KND96213.1 - 4.5e-40 136.6 0.0 6e-40 136.2 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component RhoGEF PF00621.15 KND96214.1 - 4e-11 43.1 3.5 6.2e-11 42.4 2.4 1.3 1 0 0 1 1 1 1 RhoGEF domain zf-DNL PF05180.7 KND96215.1 - 0.077 12.7 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 DNL zinc finger RRM_1 PF00076.17 KND96216.1 - 1.1e-11 44.1 0.0 1e-10 41.0 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND96216.1 - 5e-06 26.4 0.0 1.4e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Macoilin PF09726.4 KND96216.1 - 1.3 7.2 18.7 1.9 6.6 12.9 1.3 1 0 0 1 1 1 0 Transmembrane protein Pkinase PF00069.20 KND96218.1 - 5.2e-43 147.0 0.1 8e-43 146.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND96218.1 - 1.7e-24 86.2 0.0 2.4e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND96218.1 - 1.4e-08 34.0 0.0 2.3e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KND96218.1 - 0.00099 18.2 0.1 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_2 PF07653.12 KND96220.1 - 4.7e-08 32.4 0.0 1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KND96220.1 - 6.8e-07 28.5 0.4 9.5e-06 24.9 0.3 2.5 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KND96220.1 - 0.00026 20.5 0.0 0.00064 19.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain P53_tetramer PF07710.6 KND96220.1 - 0.12 11.4 2.6 0.14 11.2 0.1 2.3 2 0 0 2 2 2 0 P53 tetramerisation motif Abhydrolase_1 PF00561.15 KND96221.1 - 3.6e-11 43.0 0.0 4.6e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KND96221.1 - 1.2e-06 28.6 0.0 2.2e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND96221.1 - 1.8e-05 24.5 0.0 3.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KND96221.1 - 0.00091 19.0 0.0 0.0024 17.6 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase DUF1749 PF08538.5 KND96221.1 - 0.042 12.7 0.0 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) FAD_binding_6 PF00970.19 KND96224.1 - 4.5e-09 36.3 0.0 2.4e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Pex14_N PF04695.8 KND96224.1 - 0.01 15.8 1.4 0.013 15.5 0.1 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NAD_binding_1 PF00175.16 KND96224.1 - 0.044 14.3 0.0 7.5 7.1 0.0 2.8 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain CBFD_NFYB_HMF PF00808.18 KND96226.1 - 8.7e-11 41.7 0.1 2.2e-10 40.4 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KND96226.1 - 4.6e-05 23.4 0.1 7.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 MRP-L27 PF09809.4 KND96227.1 - 4.5e-26 90.6 0.6 9.5e-26 89.6 0.1 1.7 2 1 0 2 2 2 1 Mitochondrial ribosomal protein L27 NMT_C PF02799.10 KND96227.1 - 0.066 12.5 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain DAO PF01266.19 KND96230.1 - 2.4e-21 76.0 0.0 2.8e-21 75.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND96230.1 - 0.00094 19.1 0.1 0.0031 17.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KND96230.1 - 0.011 16.1 0.1 0.04 14.3 0.1 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KND96230.1 - 0.014 15.3 0.0 0.014 15.3 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 KND96230.1 - 0.11 11.9 0.1 0.44 9.8 0.1 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Saccharop_dh PF03435.13 KND96230.1 - 0.14 11.0 0.0 0.96 8.3 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase FAD_binding_3 PF01494.14 KND96230.1 - 0.16 10.9 0.2 0.25 10.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KND96230.1 - 0.25 10.4 1.0 0.49 9.4 0.1 1.8 2 0 0 2 2 2 0 Thi4 family GRASP55_65 PF04495.9 KND96231.1 - 3.5e-41 140.4 0.0 2.4e-37 128.0 0.0 2.2 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain PfkB PF00294.19 KND96232.1 - 3.4e-18 65.8 0.0 4.2e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KND96232.1 - 0.0001 21.6 0.0 0.00015 21.0 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase MFS_1 PF07690.11 KND96233.1 - 9.2e-38 129.8 16.5 9.2e-38 129.8 11.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND96233.1 - 1.6e-11 43.5 24.8 1e-10 40.7 7.9 3.7 3 1 0 3 3 3 2 Sugar (and other) transporter Ank PF00023.25 KND96236.1 - 5e-18 63.9 4.3 7.4e-07 28.6 0.4 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KND96236.1 - 1.7e-16 58.6 4.2 4.9e-05 23.1 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 KND96236.1 - 1.7e-16 60.2 1.9 6.7e-07 29.5 0.2 3.2 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KND96236.1 - 2e-15 56.4 7.0 9.4e-07 28.8 0.3 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KND96236.1 - 6.4e-12 45.6 6.8 0.00061 20.2 1.1 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) KilA-N PF04383.8 KND96236.1 - 2.1e-05 24.1 2.3 3.7e-05 23.3 0.1 2.4 2 1 0 2 2 2 1 KilA-N domain Cytadhesin_P30 PF07271.6 KND96237.1 - 0.054 12.7 3.1 0.091 12.0 2.1 1.5 1 0 0 1 1 1 0 Cytadhesin P30/P32 Brevenin PF03032.10 KND96237.1 - 0.16 11.7 4.4 0.45 10.3 3.1 1.8 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family OmpH PF03938.9 KND96237.1 - 0.38 10.6 11.4 0.27 11.1 5.3 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) BTV_NS2 PF04514.7 KND96237.1 - 0.99 8.2 10.4 1.2 7.9 2.3 2.1 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Anoctamin PF04547.7 KND96237.1 - 1.4 7.5 3.2 1.8 7.1 2.2 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF2956 PF11169.3 KND96237.1 - 9.1 6.3 13.1 0.98 9.4 4.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Aldedh PF00171.17 KND96238.1 - 2.4e-162 540.4 0.0 2.7e-162 540.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KND96238.1 - 0.0015 17.7 0.0 0.003 16.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) DUF1459 PF07312.6 KND96238.1 - 0.031 14.1 0.1 0.073 12.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1459) UQ_con PF00179.21 KND96241.1 - 7.5e-36 122.6 0.1 9e-36 122.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Metal_CEHH PF14455.1 KND96241.1 - 0.048 13.0 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Predicted metal binding domain RPN7 PF10602.4 KND96242.1 - 7.9e-51 171.9 4.7 1.7e-50 170.8 3.2 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KND96242.1 - 2.6e-15 56.6 0.3 2.6e-15 56.6 0.2 2.1 2 1 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 KND96242.1 - 0.00064 19.5 0.2 0.0018 18.0 0.2 1.9 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_12 PF13424.1 KND96242.1 - 0.0062 16.4 3.6 0.01 15.7 0.5 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2989 PF11207.3 KND96242.1 - 0.0088 15.5 1.4 0.0088 15.5 1.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2989) DUF3023 PF11224.3 KND96242.1 - 0.016 14.8 1.0 0.54 9.9 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3023) TPR_10 PF13374.1 KND96242.1 - 0.049 13.5 0.3 7.2 6.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF357 PF04010.8 KND96242.1 - 0.069 12.8 2.2 0.16 11.6 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF357) FeoC PF09012.5 KND96242.1 - 0.11 12.1 0.6 2.1 8.1 0.0 2.8 3 0 0 3 3 3 0 FeoC like transcriptional regulator Acyl-CoA_dh_1 PF00441.19 KND96244.1 - 1.2e-28 100.0 1.3 1.8e-28 99.5 0.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KND96244.1 - 6.4e-13 49.2 0.0 1.2e-12 48.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KND96244.1 - 1.5e-12 46.8 0.1 3.1e-12 45.8 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KND96244.1 - 3.2e-08 33.8 0.2 5.6e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain LSM PF01423.17 KND96245.1 - 8.6e-14 50.8 0.0 1.3e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 LSM domain TAF1D PF15333.1 KND96246.1 - 2.9 7.6 8.2 2.8 7.6 5.7 1.0 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D GCD14 PF08704.5 KND96248.1 - 1.3e-77 260.6 0.0 2.6e-77 259.6 0.0 1.5 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 KND96248.1 - 0.00037 20.0 0.0 0.00068 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KND96248.1 - 0.0019 17.7 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND96248.1 - 0.051 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KND96248.1 - 0.089 13.3 0.0 0.16 12.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Actin PF00022.14 KND96249.1 - 5.9e-105 350.8 0.0 6.7e-105 350.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KND96249.1 - 0.0017 16.9 0.0 0.0062 15.1 0.0 1.8 1 1 0 1 1 1 1 MreB/Mbl protein Pkinase PF00069.20 KND96250.1 - 1e-52 178.8 0.0 1.7e-52 178.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND96250.1 - 1.9e-23 82.8 0.0 3.2e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KND96250.1 - 0.017 14.8 0.0 1.8 8.2 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KND96250.1 - 0.028 13.3 0.0 0.057 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 KND96250.1 - 0.034 13.5 0.1 0.093 12.0 0.0 1.7 1 0 0 1 1 1 0 RIO1 family Peptidase_M16_C PF05193.16 KND96251.1 - 3.2e-18 66.0 0.0 1.3e-13 51.0 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KND96251.1 - 7.4e-07 29.0 0.0 1.3e-05 25.0 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Erf4 PF10256.4 KND96251.1 - 0.058 13.2 0.3 13 5.6 0.0 3.7 4 0 0 4 4 4 0 Golgin subfamily A member 7/ERF4 family Mannosyl_trans3 PF11051.3 KND96252.1 - 1.6e-73 247.4 0.1 3.1e-73 246.4 0.0 1.5 2 0 0 2 2 2 1 Mannosyltransferase putative HlyD_2 PF12700.2 KND96252.1 - 0.024 13.7 0.7 0.037 13.2 0.5 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Vps39_2 PF10367.4 KND96252.1 - 0.068 13.3 2.0 0.18 12.0 1.4 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 UFD1 PF03152.9 KND96255.1 - 5.3e-20 71.2 0.1 9.8e-20 70.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 zf-ribbon_3 PF13248.1 KND96255.1 - 0.006 15.7 0.2 0.034 13.3 0.2 2.4 1 0 0 1 1 1 1 zinc-ribbon domain Peptidase_S8 PF00082.17 KND96257.1 - 1.4e-48 165.4 10.2 1.9e-48 165.0 7.1 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KND96257.1 - 1.2e-11 45.0 0.1 3.3e-11 43.5 0.1 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 Lectin_N PF03954.9 KND96257.1 - 0.24 10.7 1.4 0.55 9.6 0.0 2.2 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain Candida_ALS PF05792.8 KND96257.1 - 0.26 11.4 2.5 1.1 9.4 0.6 2.4 2 0 0 2 2 2 0 Candida agglutinin-like (ALS) UQ_con PF00179.21 KND96258.1 - 2.1e-49 166.5 0.1 2.4e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KND96258.1 - 2.1e-06 27.4 0.0 2.6e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KND96258.1 - 0.013 15.3 0.2 0.028 14.3 0.1 1.7 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 KND96258.1 - 0.038 13.6 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain COX4 PF02936.9 KND96259.1 - 2.1e-06 27.5 0.1 4.8e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Med20 PF08612.6 KND96259.1 - 0.01 15.0 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex BCDHK_Adom3 PF10436.4 KND96262.1 - 1.4e-38 131.9 0.5 2.2e-38 131.3 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KND96262.1 - 6.8e-11 41.8 0.0 1.3e-09 37.7 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KND96262.1 - 1.7e-05 24.4 0.0 3.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HUN PF08729.5 KND96263.1 - 5.9e-14 51.6 0.2 5.9e-14 51.6 0.1 2.5 2 0 0 2 2 2 1 HPC2 and ubinuclein domain DUF896 PF05979.7 KND96263.1 - 0.11 12.1 6.2 6.4 6.4 2.6 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF896) Kinetochor_Ybp2 PF08568.5 KND96264.1 - 4.8e-138 461.2 12.7 6.6e-138 460.7 8.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin AAA_16 PF13191.1 KND96264.1 - 0.0046 16.9 0.0 0.014 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain APG12 PF04110.8 KND96265.1 - 9.4e-23 80.2 0.0 1.8e-22 79.3 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin-like autophagy protein Apg12 SUN PF03856.8 KND96266.1 - 9.3e-98 326.4 17.0 9.3e-98 326.4 11.8 1.8 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) zf-MYND PF01753.13 KND96266.1 - 0.056 13.3 1.6 0.13 12.1 1.1 1.5 1 0 0 1 1 1 0 MYND finger Pol_alpha_B_N PF08418.5 KND96266.1 - 0.1 12.1 4.5 0.14 11.6 3.1 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Sporozoite_P67 PF05642.6 KND96266.1 - 1.7 6.4 14.5 2.8 5.6 10.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_capsid PF06112.6 KND96266.1 - 1.8 8.5 23.7 5.3 7.0 16.4 1.8 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Pex14_N PF04695.8 KND96266.1 - 4.6 7.2 10.6 11 6.0 7.3 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.4 KND96266.1 - 9.3 4.3 11.4 12 4.0 7.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Pkinase PF00069.20 KND96270.1 - 8.7e-53 179.1 0.0 1.7e-52 178.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND96270.1 - 7.3e-18 64.5 0.0 2.5e-17 62.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KND96270.1 - 0.0041 16.2 0.0 0.007 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF134 PF02001.11 KND96275.1 - 0.14 12.0 0.1 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF134 XRN_N PF03159.13 KND96279.1 - 3e-76 255.9 0.1 3e-76 255.9 0.1 2.2 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus CHCH PF06747.8 KND96280.1 - 0.0013 18.5 2.5 0.0024 17.7 1.7 1.5 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 KND96280.1 - 0.032 14.2 1.3 0.048 13.6 0.9 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COG2 PF06148.6 KND96282.1 - 0.003 17.4 2.5 0.0086 15.9 0.2 2.7 2 1 1 3 3 3 2 COG (conserved oligomeric Golgi) complex component, COG2 Mito_carr PF00153.22 KND96285.1 - 1.8e-73 242.3 0.4 2.6e-25 87.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 KND96285.1 - 1.4e-05 24.0 0.2 0.048 12.9 0.1 4.6 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.1 KND96285.1 - 4e-05 23.1 0.1 0.62 9.7 0.0 4.7 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_6 PF13405.1 KND96285.1 - 0.018 14.8 14.2 4.2 7.5 0.0 6.6 8 0 0 8 8 8 0 EF-hand domain EF-hand_7 PF13499.1 KND96285.1 - 0.025 14.7 9.4 0.16 12.1 1.1 4.7 5 1 0 5 5 5 0 EF-hand domain pair Bud13 PF09736.4 KND96287.1 - 1.4e-32 112.9 2.3 1.4e-32 112.9 1.6 2.1 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex DUF4200 PF13863.1 KND96287.1 - 0.014 15.3 4.9 0.014 15.3 3.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Methyltransf_26 PF13659.1 KND96287.1 - 0.026 14.5 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PagL PF09411.5 KND96287.1 - 0.047 13.7 0.0 4.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Lipid A 3-O-deacylase (PagL) Telomere_Sde2 PF13019.1 KND96287.1 - 6.3 6.4 13.7 2.4 7.8 0.5 2.5 2 1 0 2 2 2 0 Telomere stability and silencing Nucleoporin_FG PF13634.1 KND96288.1 - 3.4e-29 101.3 142.6 2e-12 47.3 36.5 3.4 1 1 2 3 3 3 3 Nucleoporin FG repeat region IncA PF04156.9 KND96288.1 - 0.016 14.7 6.6 0.067 12.7 3.5 2.5 1 1 0 1 1 1 0 IncA protein DUF3818 PF12825.2 KND96288.1 - 0.026 13.2 2.5 0.04 12.6 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Med9 PF07544.8 KND96288.1 - 0.026 14.2 1.5 0.089 12.5 0.2 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF948 PF06103.6 KND96288.1 - 0.047 13.5 3.6 0.11 12.3 0.2 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) MCPsignal PF00015.16 KND96288.1 - 0.12 11.9 0.7 0.19 11.2 0.5 1.4 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.7 KND96288.1 - 0.54 10.0 4.0 0.77 9.5 0.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.7 KND96288.1 - 0.65 9.7 3.8 0.89 9.3 0.3 2.1 2 0 0 2 2 2 0 Laminin Domain II TMF_DNA_bd PF12329.3 KND96288.1 - 1.7 8.4 4.7 9.5 6.1 0.2 3.1 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.4 KND96288.1 - 3.1 7.9 6.0 4.4 7.4 1.3 2.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Asp PF00026.18 KND96290.1 - 2.1e-62 211.1 1.5 2.5e-62 210.9 1.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KND96290.1 - 1e-07 32.0 0.0 2.4e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KND96290.1 - 0.00063 20.1 0.5 0.043 14.3 0.1 2.7 2 1 0 2 2 2 1 Aspartyl protease Sigma_reg_N PF13800.1 KND96292.1 - 0.099 12.6 0.3 0.27 11.3 0.1 1.7 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DAG1 PF05454.6 KND96292.1 - 0.13 11.4 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DDDD PF10161.4 KND96292.1 - 0.57 9.8 2.0 15 5.2 0.0 2.1 1 1 1 2 2 2 0 Putative mitochondrial precursor protein DUF972 PF06156.8 KND96293.1 - 0.0006 20.1 0.5 0.0006 20.1 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF972) Kinetocho_Slk19 PF12709.2 KND96293.1 - 0.024 14.6 1.5 0.024 14.6 1.0 2.5 3 0 0 3 3 3 0 Central kinetochore-associated DUF3969 PF13108.1 KND96293.1 - 0.087 12.4 0.2 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3969) V_ATPase_I PF01496.14 KND96293.1 - 0.1 10.4 1.3 0.15 9.8 0.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF904 PF06005.7 KND96293.1 - 0.34 11.2 6.3 0.3 11.3 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 KND96293.1 - 0.51 9.8 5.5 1.2 8.6 2.2 2.4 2 0 0 2 2 2 0 Septum formation initiator Synapsin_N PF10581.4 KND96293.1 - 0.78 9.6 2.9 0.53 10.1 0.2 2.1 2 0 0 2 2 2 0 Synapsin N-terminal KLRAQ PF10205.4 KND96293.1 - 1.1 9.3 8.5 0.045 13.7 1.5 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Cut8_N PF14482.1 KND96293.1 - 2.9 7.9 10.2 0.37 10.8 1.3 3.1 3 0 0 3 3 3 0 Cut8 proteasome-binding domain COX1 PF00115.15 KND96294.1 - 0.024 13.2 0.8 0.029 13.0 0.6 1.0 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I PUF PF00806.14 KND96295.1 - 1.3e-49 162.9 23.8 1.2e-07 30.8 0.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Sas10_Utp3 PF04000.10 KND96297.1 - 5.1e-08 33.0 3.3 5.1e-08 33.0 2.3 2.2 2 1 0 2 2 2 1 Sas10/Utp3/C1D family DUF2457 PF10446.4 KND96297.1 - 0.0023 16.7 16.1 0.0055 15.5 11.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.5 KND96297.1 - 0.013 15.6 14.7 0.037 14.2 10.2 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDV3 PF15359.1 KND96297.1 - 0.019 15.0 4.9 0.046 13.8 3.4 1.7 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 Sigma70_ner PF04546.8 KND96297.1 - 0.2 11.2 17.0 0.53 9.8 11.8 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region Sporozoite_P67 PF05642.6 KND96297.1 - 0.26 9.1 5.9 0.36 8.6 4.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RNA_pol_3_Rpc31 PF11705.3 KND96297.1 - 0.62 9.9 22.9 0.1 12.5 11.3 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF4611 PF15387.1 KND96297.1 - 0.73 10.0 17.5 0.73 10.0 10.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) DUF3245 PF11595.3 KND96297.1 - 0.88 9.8 16.4 1.7 8.9 8.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3245) Cytomega_UL84 PF06284.6 KND96297.1 - 0.92 7.8 3.9 1.6 7.0 2.7 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein PBP_sp32 PF07222.7 KND96297.1 - 2.1 7.4 10.0 5.2 6.1 6.9 1.6 1 0 0 1 1 1 0 Proacrosin binding protein sp32 TRAP_alpha PF03896.11 KND96297.1 - 2.7 6.9 12.8 5.1 6.0 8.9 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit HAUS6_N PF14661.1 KND96297.1 - 2.8 7.2 9.2 0.72 9.1 3.3 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Nucleoplasmin PF03066.10 KND96297.1 - 3.8 7.0 18.0 7.4 6.0 12.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 KND96297.1 - 6.2 5.9 15.2 1.3 8.2 8.1 1.5 2 0 0 2 2 2 0 NOA36 protein DUF3449 PF11931.3 KND96297.1 - 9.2 5.7 12.3 0.52 9.8 3.9 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) Ribosomal_S8e PF01201.17 KND96299.1 - 1.9e-40 138.0 6.5 4e-40 137.0 4.5 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e Fungal_trans PF04082.13 KND96300.1 - 2.6e-63 213.3 3.5 4.3e-63 212.6 2.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KND96300.1 - 1.4e-07 31.4 9.6 0.00031 20.9 1.8 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND96300.1 - 2.3e-07 30.6 9.1 1.2e-05 25.3 1.8 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger DUF3340 PF11818.3 KND96300.1 - 0.72 9.7 4.0 1.5 8.7 2.8 1.4 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Rap1-DNA-bind PF09197.5 KND96301.1 - 0.0058 17.1 2.6 0.013 16.0 0.0 2.4 3 0 0 3 3 3 1 Rap1, DNA-binding Pepsin-I3 PF06394.8 KND96301.1 - 0.028 14.0 0.3 0.098 12.3 0.1 2.0 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain T2SE_Nter PF05157.10 KND96301.1 - 0.037 14.0 0.7 0.78 9.8 0.1 2.3 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein E, N-terminal domain zf-RING_2 PF13639.1 KND96303.1 - 9.5e-10 38.1 4.8 3.4e-08 33.1 1.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KND96303.1 - 2.5e-08 33.9 2.2 6.3e-07 29.4 0.4 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KND96303.1 - 1.1e-05 24.9 6.0 3.8e-05 23.2 1.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KND96303.1 - 4.9e-05 22.9 3.1 0.0025 17.4 0.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND96303.1 - 0.0002 20.9 4.3 0.0026 17.4 0.9 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KND96303.1 - 0.0002 21.2 7.0 0.00061 19.7 1.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KND96303.1 - 0.00055 19.7 1.4 0.0011 18.7 0.3 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 KND96303.1 - 0.015 15.2 4.7 0.56 10.2 1.0 3.0 2 1 0 2 2 2 0 FANCL C-terminal domain BIR PF00653.16 KND96303.1 - 0.015 15.6 0.4 0.015 15.6 0.3 2.4 2 1 1 3 3 3 0 Inhibitor of Apoptosis domain zf-RING_UBOX PF13445.1 KND96303.1 - 0.022 14.4 8.5 0.027 14.1 0.8 3.0 2 1 0 2 2 2 0 RING-type zinc-finger DUF329 PF03884.9 KND96303.1 - 0.043 13.3 1.3 2.8 7.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zf-Nse PF11789.3 KND96303.1 - 0.043 13.3 5.0 0.12 11.9 0.9 3.0 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-Di19 PF05605.7 KND96303.1 - 0.044 13.9 0.8 6.2 7.0 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DRP PF06044.7 KND96303.1 - 0.085 11.8 1.5 2.9 6.8 0.1 2.2 2 0 0 2 2 2 0 Dam-replacing family DUF1644 PF07800.7 KND96303.1 - 0.1 12.4 8.4 2.8 7.7 2.9 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1644) zf-RING_4 PF14570.1 KND96303.1 - 0.28 10.8 3.3 1.9 8.1 0.3 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KND96303.1 - 1.4 8.8 5.6 2.1 8.3 1.3 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zinc_ribbon_5 PF13719.1 KND96303.1 - 2.4 7.8 7.1 3.9 7.1 0.3 3.7 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KND96303.1 - 2.7 7.7 7.4 3.7 7.3 0.3 3.7 4 0 0 4 4 4 0 zinc-ribbon domain FYDLN_acid PF09538.5 KND96303.1 - 4.9 7.7 8.1 0.95 10.0 0.3 3.1 4 0 0 4 4 4 0 Protein of unknown function (FYDLN_acid) DUF4514 PF14986.1 KND96304.1 - 0.083 12.7 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) CSTF2_hinge PF14327.1 KND96305.1 - 8.2e-24 83.5 3.7 8.2e-24 83.5 2.6 2.4 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_6 PF14259.1 KND96305.1 - 6.7e-10 38.8 0.0 1.2e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KND96305.1 - 6.8e-10 38.4 0.0 1.1e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 KND96305.1 - 1.6e-05 24.1 4.1 1.6e-05 24.1 2.8 2.8 2 1 1 3 3 3 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 KND96305.1 - 7.6e-05 22.4 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GLTSCR1 PF15249.1 KND96306.1 - 0.046 13.8 2.2 0.05 13.7 0.1 2.2 2 0 0 2 2 2 0 Glioma tumor suppressor candidate region Sulfatase_C PF14707.1 KND96306.1 - 0.061 13.6 0.4 0.061 13.6 0.3 1.9 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase Psu PF07455.6 KND96306.1 - 0.7 9.3 5.4 0.3 10.5 1.0 2.1 2 1 0 2 2 2 0 Phage polarity suppression protein (Psu) DUF607 PF04678.8 KND96306.1 - 0.87 9.4 4.7 0.3 10.9 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF607 DUF3391 PF11871.3 KND96306.1 - 1.1 9.4 8.3 0.26 11.5 1.4 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3391) TMCO5 PF14992.1 KND96306.1 - 1.3 8.0 13.7 0.025 13.7 2.5 2.1 2 0 0 2 2 2 0 TMCO5 family bZIP_2 PF07716.10 KND96306.1 - 5.6 6.8 15.0 7.4 6.4 0.9 3.1 2 1 1 3 3 3 0 Basic region leucine zipper RNA_pol_Rpc34 PF05158.7 KND96307.1 - 7.1e-88 294.9 0.5 7.9e-88 294.7 0.3 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.7 KND96307.1 - 0.019 14.8 0.1 0.041 13.7 0.1 1.6 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC RPA_C PF08784.6 KND96307.1 - 0.063 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Replication protein A C terminal Cyclin_C PF02984.14 KND96307.1 - 0.074 12.9 0.3 0.15 11.9 0.2 1.5 1 0 0 1 1 1 0 Cyclin, C-terminal domain UPF0086 PF01868.11 KND96308.1 - 1.8e-10 40.2 0.1 2.7e-07 30.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function UPF0086 BPL_LplA_LipB PF03099.14 KND96309.1 - 5.7e-19 68.3 0.0 1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF1989 PF09347.5 KND96310.1 - 6.7e-53 178.5 0.0 1e-52 177.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) FeS PF04060.8 KND96310.1 - 0.037 13.5 0.0 0.077 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative Fe-S cluster DUF2975 PF11188.3 KND96311.1 - 0.12 12.1 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) NAD_binding_2 PF03446.10 KND96312.1 - 1.9e-34 118.8 0.0 2.7e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KND96312.1 - 9e-19 67.7 0.0 1.4e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KND96312.1 - 0.00068 20.0 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Nab2 PF11517.3 KND96312.1 - 0.006 16.6 0.0 0.017 15.2 0.0 1.7 1 1 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) GFO_IDH_MocA PF01408.17 KND96312.1 - 0.04 14.4 0.0 0.31 11.5 0.0 2.2 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Arrestin_C PF02752.17 KND96313.1 - 2.6e-15 56.7 0.0 2.2e-14 53.7 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KND96313.1 - 6.3e-07 29.3 0.0 0.00033 20.4 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain TPR_11 PF13414.1 KND96314.1 - 3e-18 65.2 19.1 0.00061 19.3 0.0 8.4 8 0 0 8 8 8 5 TPR repeat TPR_19 PF14559.1 KND96314.1 - 1.1e-15 57.7 11.5 4.3e-05 23.7 0.3 6.4 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 KND96314.1 - 1.6e-14 53.0 4.6 0.051 14.2 0.0 9.3 5 2 5 10 10 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 KND96314.1 - 1.6e-13 50.3 15.8 2.3e-05 24.2 0.1 7.5 4 3 3 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 KND96314.1 - 3.3e-13 49.9 7.8 0.023 15.3 0.1 6.9 5 2 3 8 8 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 KND96314.1 - 1.8e-11 42.9 4.7 0.042 13.6 0.0 8.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.12 KND96314.1 - 1.3e-10 40.3 16.1 0.57 10.2 0.0 9.8 10 0 0 10 10 9 2 Tetratricopeptide repeat Apc3 PF12895.2 KND96314.1 - 4e-10 39.6 10.4 4.1e-05 23.6 0.6 5.1 4 1 2 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KND96314.1 - 4.3e-08 33.0 4.7 2 9.0 0.2 7.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 KND96314.1 - 8.7e-08 31.4 15.7 0.58 9.8 0.0 8.4 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.1 KND96314.1 - 6e-06 26.0 13.4 1.9 8.9 0.0 8.8 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_20 PF14561.1 KND96314.1 - 0.0054 16.8 12.9 0.5 10.5 0.0 5.6 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KND96314.1 - 0.022 14.5 6.8 24 5.0 0.0 6.7 8 0 0 8 8 6 0 Tetratricopeptide repeat RNase_P_Rpp14 PF01900.14 KND96315.1 - 1.3e-34 118.3 0.0 1.6e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family plasmid_Toxin PF12703.2 KND96315.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Toxin of toxin-antitoxin type 1 system SPT2 PF08243.6 KND96316.1 - 1.2e-25 90.0 23.2 1.2e-25 90.0 16.1 2.3 2 0 0 2 2 2 1 SPT2 chromatin protein DUF3499 PF12005.3 KND96316.1 - 5.5 7.1 8.0 13 5.9 1.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) Init_tRNA_PT PF04179.7 KND96317.1 - 2.2e-130 435.5 0.0 2.5e-130 435.3 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Pox_A32 PF04665.7 KND96317.1 - 0.08 12.2 0.4 0.12 11.6 0.3 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein FSH1 PF03959.8 KND96318.1 - 2.9e-45 154.3 0.0 3.3e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KND96318.1 - 1e-05 25.2 0.0 1.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 KND96318.1 - 0.00014 21.6 0.0 0.00021 21.0 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 KND96318.1 - 0.00021 20.7 0.0 0.12 11.8 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KND96318.1 - 0.00028 20.8 0.0 0.0071 16.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2235 PF09994.4 KND96318.1 - 0.0015 17.9 0.0 0.0017 17.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Lipase_3 PF01764.20 KND96318.1 - 0.016 14.7 0.0 0.41 10.2 0.0 2.1 2 0 0 2 2 2 0 Lipase (class 3) Pox_MCEL PF03291.11 KND96321.1 - 2.8e-92 309.1 0.0 3.7e-92 308.7 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_12 PF08242.7 KND96321.1 - 1.4e-06 28.7 0.0 6.7e-06 26.5 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND96321.1 - 8e-06 26.2 0.0 0.1 13.0 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 KND96321.1 - 8.3e-06 26.1 0.0 5.4e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND96321.1 - 2.6e-05 23.8 0.1 9.4e-05 22.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND96321.1 - 0.00012 21.8 0.0 0.00024 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND96321.1 - 0.00015 22.3 0.0 0.00033 21.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 KND96321.1 - 0.0043 16.5 0.0 0.007 15.8 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_4 PF02390.12 KND96321.1 - 0.02 13.9 0.0 0.049 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Vel1p PF10339.4 KND96321.1 - 0.031 13.4 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Yeast-specific zinc responsive NNMT_PNMT_TEMT PF01234.12 KND96321.1 - 0.098 11.6 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Exo_endo_phos PF03372.18 KND96322.1 - 4.4e-10 39.9 0.0 5.6e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3449 PF11931.3 KND96323.1 - 7.1e-62 208.4 0.2 7.1e-62 208.4 0.1 2.5 3 1 0 3 3 3 1 Domain of unknown function (DUF3449) zf-met PF12874.2 KND96323.1 - 8e-11 41.7 7.8 8.7e-07 28.9 1.0 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KND96323.1 - 1.9e-08 34.2 11.1 1.9e-05 24.6 3.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KND96323.1 - 4.3e-05 23.5 1.9 0.0079 16.2 0.4 2.9 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 KND96323.1 - 0.029 13.9 2.2 0.089 12.3 1.5 1.8 1 0 0 1 1 1 0 U1 zinc finger zf-BED PF02892.10 KND96323.1 - 0.2 11.4 3.0 0.25 11.1 0.1 2.3 2 0 0 2 2 2 0 BED zinc finger PseudoU_synth_2 PF00849.17 KND96324.1 - 2.1e-31 108.9 0.1 3.3e-31 108.3 0.1 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase dCMP_cyt_deam_1 PF00383.17 KND96324.1 - 1.3e-17 63.2 0.0 2.9e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region S4 PF01479.20 KND96324.1 - 0.062 12.7 0.1 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 S4 domain PalH PF08733.5 KND96325.1 - 8.8e-94 314.1 18.2 1.1e-93 313.9 12.6 1.1 1 0 0 1 1 1 1 PalH/RIM21 RabGAP-TBC PF00566.13 KND96327.1 - 1.3e-39 135.9 0.1 2.2e-39 135.1 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Got1 PF04178.7 KND96329.1 - 3.3e-31 107.8 18.9 4.8e-31 107.3 13.1 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family B PF02216.11 KND96329.1 - 0.12 12.1 0.2 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 B domain Imp-YgjV PF10688.4 KND96329.1 - 0.15 11.4 14.7 0.22 10.9 10.2 1.2 1 0 0 1 1 1 0 Bacterial inner membrane protein DUF3796 PF12676.2 KND96329.1 - 7.7 6.7 10.0 24 5.1 6.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3796) NARP1 PF12569.3 KND96330.1 - 1e-127 427.1 25.4 1.3e-94 317.8 0.7 4.6 3 2 1 4 4 4 3 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 KND96330.1 - 8.7e-14 51.7 13.1 0.0036 17.9 0.0 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 KND96330.1 - 1.8e-12 46.1 17.7 0.04 13.8 0.0 9.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 KND96330.1 - 2.2e-09 36.8 23.3 9.4e-06 25.1 1.1 6.2 5 1 2 7 7 7 3 TPR repeat TPR_19 PF14559.1 KND96330.1 - 9.7e-08 32.2 18.7 0.0043 17.3 0.2 6.8 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 KND96330.1 - 3.5e-07 30.2 7.9 1.8 9.3 0.0 7.2 8 0 0 8 8 6 3 Tetratricopeptide repeat Apc3 PF12895.2 KND96330.1 - 2.4e-05 24.3 27.0 0.0049 16.9 1.5 6.3 4 3 4 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KND96330.1 - 0.00012 21.9 17.2 0.35 10.8 0.1 6.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KND96330.1 - 0.0099 16.0 8.9 0.32 11.3 0.0 6.0 6 1 0 6 6 6 1 Tetratricopeptide repeat Rapsyn_N PF10579.4 KND96330.1 - 0.019 14.7 0.0 0.59 9.9 0.0 2.9 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region TPR_8 PF13181.1 KND96330.1 - 0.029 14.1 22.2 5.5 7.0 0.0 8.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.23 KND96330.1 - 0.11 12.2 25.1 13 5.6 0.0 7.6 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 KND96330.1 - 0.68 10.5 11.3 2.5 8.7 0.1 6.3 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 KND96330.1 - 3.8 7.5 7.8 5.2 7.1 0.0 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat Sel1 PF08238.7 KND96330.1 - 4.7 7.9 7.4 0.68 10.6 0.3 3.3 4 0 0 4 4 3 0 Sel1 repeat Fungal_trans PF04082.13 KND96333.1 - 2.5e-12 46.2 0.4 6.5e-12 44.8 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND96333.1 - 7.1e-10 38.6 11.3 1.2e-09 37.8 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND96334.1 - 7.6e-09 34.8 0.3 7.6e-09 34.8 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND96334.1 - 1.8e-07 30.9 14.4 1.8e-07 30.9 10.0 2.5 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_11 PF13414.1 KND96335.1 - 4.6e-57 189.5 28.2 2.2e-18 65.6 0.3 6.2 5 1 2 7 7 7 6 TPR repeat TPR_1 PF00515.23 KND96335.1 - 3.7e-46 152.9 31.6 8.5e-08 31.4 0.0 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 KND96335.1 - 3.7e-37 123.2 31.9 0.00012 21.6 0.0 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.1 KND96335.1 - 2.2e-24 85.4 8.6 3.4e-06 27.5 1.4 6.3 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 KND96335.1 - 6.4e-23 80.4 17.2 2.4e-09 37.0 0.3 5.8 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 KND96335.1 - 1.8e-21 74.2 20.8 0.00079 19.0 0.0 8.6 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.1 KND96335.1 - 7.1e-17 60.3 7.4 0.12 13.0 0.1 9.5 4 3 5 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 KND96335.1 - 1.7e-13 50.6 19.0 0.00053 20.2 0.7 6.8 4 3 3 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 KND96335.1 - 5.8e-10 38.5 15.8 0.018 15.2 0.0 8.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 KND96335.1 - 2.5e-09 36.8 0.8 0.00028 20.6 0.0 4.3 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KND96335.1 - 3.7e-09 35.7 16.3 0.071 12.9 0.1 8.0 7 2 1 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 KND96335.1 - 1.2e-07 31.7 16.1 0.025 14.7 0.9 4.9 4 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KND96335.1 - 8.9e-06 25.8 18.1 4.9 7.8 0.0 8.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_21 PF09976.4 KND96335.1 - 0.00012 22.0 17.4 0.14 12.0 0.9 5.3 4 1 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 KND96335.1 - 0.0053 16.6 1.1 17 5.5 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF3808 PF10300.4 KND96335.1 - 0.011 14.3 1.3 0.033 12.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) Fis1_TPR_C PF14853.1 KND96335.1 - 0.023 14.5 5.4 7.9 6.4 0.0 4.7 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat DUF357 PF04010.8 KND96335.1 - 0.029 14.0 2.8 0.6 9.8 0.3 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF357) PPR_2 PF13041.1 KND96335.1 - 0.03 14.3 1.0 30 4.6 0.0 4.4 4 1 0 4 4 3 0 PPR repeat family Inhibitor_I9 PF05922.11 KND96335.1 - 0.037 14.5 2.3 0.063 13.8 0.0 2.6 3 0 0 3 3 1 0 Peptidase inhibitor I9 SHNi-TPR PF10516.4 KND96335.1 - 0.049 12.8 8.9 2.2 7.6 0.0 4.8 6 0 0 6 6 6 0 SHNi-TPR SAP25 PF15476.1 KND96335.1 - 0.12 11.9 3.3 0.21 11.0 2.3 1.3 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP25 PPR PF01535.15 KND96335.1 - 0.31 11.0 1.9 82 3.5 0.0 5.0 5 1 1 6 6 4 0 PPR repeat bZIP_1 PF00170.16 KND96336.1 - 2.4e-07 30.6 7.9 5e-07 29.5 5.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 KND96336.1 - 0.065 12.8 0.3 0.12 11.9 0.2 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF972 PF06156.8 KND96336.1 - 0.2 12.0 4.5 6.1 7.2 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 KND96336.1 - 5.8 6.8 19.4 0.13 12.0 6.4 2.5 2 0 0 2 2 2 0 Basic region leucine zipper Cyt-b5 PF00173.23 KND96337.1 - 1.6e-23 82.2 0.0 2.3e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2970 PF11174.3 KND96337.1 - 0.0087 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2970) Birna_VP5 PF03042.9 KND96337.1 - 0.068 12.6 0.1 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Birnavirus VP5 protein DUF2196 PF09962.4 KND96337.1 - 0.094 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2196) DUF3357 PF11837.3 KND96337.1 - 0.096 12.5 0.4 0.18 11.6 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) ArfGap PF01412.13 KND96339.1 - 3.2e-39 133.3 1.1 5.8e-39 132.4 0.8 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Mito_carr PF00153.22 KND96341.1 - 1.6e-44 149.4 7.1 1.9e-18 65.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Nop14 PF04147.7 KND96342.1 - 2.5e-215 717.1 66.9 6.3e-126 421.4 15.0 2.0 1 1 1 2 2 2 2 Nop14-like family APG9 PF04109.11 KND96343.1 - 3.5e-158 526.3 9.5 4.7e-158 525.9 6.6 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 CGGC PF08821.6 KND96344.1 - 0.081 12.9 0.1 0.088 12.8 0.1 1.2 1 0 0 1 1 1 0 CGGC domain Epimerase PF01370.16 KND96345.1 - 4e-19 68.9 0.0 5.8e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KND96345.1 - 1.4e-13 50.2 0.0 1.9e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KND96345.1 - 2e-10 40.9 0.5 4.3e-10 39.9 0.3 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KND96345.1 - 1.1e-08 34.2 0.2 4.7e-07 28.9 0.2 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KND96345.1 - 8.5e-06 25.7 0.0 2.1e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KND96345.1 - 0.00023 20.1 0.5 0.00041 19.3 0.1 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KND96345.1 - 0.0037 16.5 0.3 0.0085 15.3 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family DapB_N PF01113.15 KND96345.1 - 0.037 13.9 0.1 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 KND96345.1 - 0.039 13.6 0.1 0.23 11.1 0.0 2.1 1 1 0 1 1 1 0 KR domain Pigment_DH PF06324.6 KND96345.1 - 0.29 10.4 1.4 0.55 9.5 1.0 1.4 1 0 0 1 1 1 0 Pigment-dispersing hormone (PDH) Mito_carr PF00153.22 KND96348.1 - 2.4e-71 235.4 4.3 3.2e-25 87.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HAT PF02184.11 KND96348.1 - 1.3 8.8 3.7 0.85 9.4 0.4 2.2 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat MFS_1 PF07690.11 KND96349.1 - 9.9e-28 96.8 24.5 1.3e-27 96.4 17.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF77 PF01910.12 KND96353.1 - 1.4e-26 91.9 0.2 1.6e-26 91.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 Glyco_transf_8 PF01501.15 KND96354.1 - 1.2e-35 123.0 0.0 1.6e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KND96354.1 - 0.00074 18.9 0.2 0.0012 18.2 0.1 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative COG2 PF06148.6 KND96354.1 - 0.44 10.4 2.9 2.5 7.9 0.3 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Septin PF00735.13 KND96355.1 - 2.4e-108 361.4 0.1 2.9e-108 361.1 0.1 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KND96355.1 - 4.7e-08 32.9 0.1 8e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KND96355.1 - 2.3e-06 26.8 0.0 4.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KND96355.1 - 6.3e-05 22.1 0.1 0.00011 21.3 0.1 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 KND96355.1 - 0.00018 21.0 0.1 0.0008 18.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 KND96355.1 - 0.0012 18.3 0.2 0.039 13.4 0.2 2.8 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 KND96355.1 - 0.0033 17.2 0.8 1.3 8.8 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 KND96355.1 - 0.0051 17.2 0.1 0.01 16.3 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein AAA_10 PF12846.2 KND96355.1 - 0.0058 16.1 0.0 0.0082 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 KND96355.1 - 0.0058 16.7 0.1 0.041 14.0 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.1 KND96355.1 - 0.0068 16.0 0.0 0.018 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KND96355.1 - 0.0073 16.6 0.3 0.017 15.4 0.2 1.6 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 KND96355.1 - 0.0092 15.9 0.1 0.032 14.2 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 KND96355.1 - 0.01 15.5 0.1 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Gtr1_RagA PF04670.7 KND96355.1 - 0.011 14.8 0.0 0.034 13.2 0.0 1.8 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region T2SE PF00437.15 KND96355.1 - 0.018 13.9 0.1 0.028 13.3 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 KND96355.1 - 0.023 14.1 0.1 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NB-ARC PF00931.17 KND96355.1 - 0.035 12.9 0.1 0.063 12.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain IIGP PF05049.8 KND96355.1 - 0.065 12.0 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) NACHT PF05729.7 KND96355.1 - 0.1 12.2 0.1 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Pox_A32 PF04665.7 KND96355.1 - 0.12 11.6 0.2 0.22 10.7 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein Ribosomal_L32p PF01783.18 KND96357.1 - 2.5e-12 46.7 3.8 6.9e-12 45.3 2.7 1.8 1 0 0 1 1 1 1 Ribosomal L32p protein family zinc_ribbon_5 PF13719.1 KND96357.1 - 0.0094 15.5 1.2 0.013 15.0 0.1 1.8 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KND96357.1 - 0.011 15.3 1.1 0.018 14.7 0.1 1.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-UBR PF02207.15 KND96357.1 - 0.018 14.7 0.3 0.027 14.1 0.2 1.2 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-ribbon_3 PF13248.1 KND96357.1 - 0.063 12.5 1.8 0.096 11.9 1.3 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Atg14 PF10186.4 KND96357.1 - 0.075 11.9 0.6 0.1 11.5 0.1 1.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3656 PF12392.3 KND96357.1 - 0.095 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Collagenase Elf1 PF05129.8 KND96357.1 - 0.86 9.3 3.7 5.8 6.6 2.5 2.1 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Cupin_8 PF13621.1 KND96358.1 - 9.7e-12 44.9 0.2 3.7e-11 43.0 0.0 2.0 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.17 KND96358.1 - 1.6e-08 34.7 0.2 4.6e-07 30.0 0.1 2.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 KND96358.1 - 1.6e-07 30.9 0.0 5e-07 29.3 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KND96358.1 - 0.017 14.7 0.0 0.053 13.1 0.0 1.9 1 0 0 1 1 1 0 F-box domain PNPOx_C PF10590.4 KND96360.1 - 1.2e-19 69.4 1.6 2.6e-19 68.4 1.1 1.6 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 KND96360.1 - 7.5e-11 41.9 0.0 1.2e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_red PF03358.10 KND96361.1 - 3.5e-11 42.8 0.0 4.8e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 KND96361.1 - 1.4e-06 28.3 0.0 2.4e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 KND96361.1 - 7.1e-05 22.4 0.0 9.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Bacteriocin_IIc PF10439.4 KND96361.1 - 9.1 6.4 8.0 1.1 9.4 1.5 2.4 3 0 0 3 3 3 0 Bacteriocin class II with double-glycine leader peptide Pkinase PF00069.20 KND96363.1 - 1e-67 228.0 0.0 1e-67 228.0 0.0 2.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND96363.1 - 5e-34 117.5 0.0 6.6e-32 110.5 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 KND96363.1 - 1.8e-16 59.3 0.2 7.8e-16 57.2 0.0 2.1 2 0 0 2 2 2 1 Kinase associated domain 1 Kinase-like PF14531.1 KND96363.1 - 1.6e-06 27.2 0.0 5.4e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KND96363.1 - 4.6e-05 22.5 0.0 0.0001 21.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KND96363.1 - 0.062 12.1 0.1 0.25 10.1 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 WaaY PF06176.6 KND96363.1 - 0.14 11.4 0.1 0.27 10.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.18 KND96363.1 - 0.76 9.4 7.7 0.087 12.5 0.5 2.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family Dicty_REP PF05086.7 KND96363.1 - 2.7 5.6 8.9 4.9 4.7 6.2 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein UPF0014 PF03649.8 KND96365.1 - 0.047 12.8 0.0 0.053 12.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0014) LSM PF01423.17 KND96366.1 - 7.3e-17 60.6 0.4 8.5e-17 60.4 0.3 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KND96366.1 - 3.2e-05 23.7 0.1 3.5e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 KND96366.1 - 0.15 11.8 0.3 0.18 11.6 0.2 1.2 1 1 0 1 1 1 0 Scd6-like Sm domain COPI_assoc PF08507.5 KND96367.1 - 0.049 13.3 1.9 0.06 13.0 1.3 1.2 1 0 0 1 1 1 0 COPI associated protein Ras PF00071.17 KND96368.1 - 2.8e-58 195.9 0.0 3.3e-58 195.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KND96368.1 - 3.3e-20 72.7 0.0 5.1e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KND96368.1 - 1.1e-14 54.0 0.0 1.4e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KND96368.1 - 1.3e-06 28.3 0.0 1.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KND96368.1 - 1.3e-06 27.7 0.1 1.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 KND96368.1 - 9.7e-06 24.9 0.0 0.00017 20.9 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 KND96368.1 - 1.1e-05 24.7 0.0 1.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KND96368.1 - 0.00024 20.5 0.0 0.0015 17.9 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KND96368.1 - 0.0034 16.6 0.1 0.0083 15.3 0.0 1.7 2 1 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KND96368.1 - 0.023 14.6 0.3 0.088 12.7 0.2 2.2 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 KND96368.1 - 0.041 13.3 0.0 0.6 9.5 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 KND96368.1 - 0.067 13.3 0.0 0.22 11.6 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.1 KND96368.1 - 0.11 12.0 0.0 0.35 10.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain EOS1 PF12326.3 KND96369.1 - 3.6e-54 182.4 7.5 6.5e-54 181.6 5.2 1.4 1 0 0 1 1 1 1 N-glycosylation protein Ribosomal_S13 PF00416.17 KND96370.1 - 1.6e-22 79.9 1.1 1.8e-22 79.8 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 KND96370.1 - 0.001 17.6 0.0 0.0011 17.5 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) TRAUB PF08164.7 KND96371.1 - 1.5e-27 95.4 0.0 1.5e-27 95.4 0.0 2.5 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 KND96371.1 - 1.5e-26 93.0 0.4 1.5e-26 93.0 0.3 3.5 4 1 0 4 4 4 1 Apoptosis antagonizing transcription factor IncA PF04156.9 KND96371.1 - 1.4 8.5 8.5 3.4 7.2 1.0 2.8 2 0 0 2 2 2 0 IncA protein OTU PF02338.14 KND96373.1 - 3.9e-11 43.6 0.0 8e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KND96373.1 - 3.2e-07 29.9 0.0 0.0038 16.6 0.0 2.6 1 1 2 3 3 3 2 Peptidase C65 Otubain Motile_Sperm PF00635.21 KND96373.1 - 0.026 14.1 0.3 0.06 12.9 0.0 1.7 2 0 0 2 2 2 0 MSP (Major sperm protein) domain zf-C2H2_jaz PF12171.3 KND96374.1 - 1.5e-07 31.3 3.0 3e-07 30.3 2.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KND96374.1 - 0.033 14.2 0.7 0.05 13.7 0.5 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Frankia_peptide PF14407.1 KND96374.1 - 0.097 12.4 0.7 15 5.4 0.0 2.4 1 1 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. zf-met PF12874.2 KND96374.1 - 0.11 12.7 0.9 0.18 12.0 0.6 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type PRT_C PF08372.5 KND96374.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Ribosomal_L16 PF00252.13 KND96376.1 - 1.2e-31 109.1 0.1 1.6e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF95 PF01944.12 KND96377.1 - 0.025 14.2 0.0 0.031 13.9 0.0 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF95 PepSY_TM_2 PF13703.1 KND96377.1 - 0.055 13.6 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix RCC1 PF00415.13 KND96378.1 - 2.3e-15 56.5 0.2 0.00016 21.8 0.0 5.5 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KND96378.1 - 7.3e-12 44.5 0.6 0.00019 20.9 0.1 3.7 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat DUF1640 PF07798.6 KND96379.1 - 1.2e-63 214.3 11.5 1.4e-63 214.1 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HalX PF08663.5 KND96379.1 - 0.0011 18.9 1.7 0.54 10.2 0.1 2.4 2 0 0 2 2 2 2 HalX domain YfbU PF03887.9 KND96379.1 - 0.034 13.6 0.2 0.063 12.8 0.1 1.5 1 1 0 1 1 1 0 YfbU domain ADIP PF11559.3 KND96379.1 - 0.059 13.2 13.3 0.95 9.3 5.8 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding HALZ PF02183.13 KND96379.1 - 0.07 12.8 5.4 0.2 11.4 2.8 2.4 2 1 0 2 2 2 0 Homeobox associated leucine zipper TraC PF07820.7 KND96379.1 - 0.11 12.6 4.0 1.9 8.7 1.3 2.8 1 1 1 2 2 2 0 TraC-like protein Ded_cyto PF06920.8 KND96379.1 - 0.11 11.7 6.2 0.035 13.4 1.4 2.0 2 1 0 2 2 2 0 Dedicator of cytokinesis Reo_sigmaC PF04582.7 KND96379.1 - 0.12 11.5 4.2 0.087 11.9 1.5 1.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF1319 PF07028.6 KND96379.1 - 0.13 12.4 11.7 0.42 10.8 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1319) FlaC_arch PF05377.6 KND96379.1 - 0.21 11.5 3.9 11 6.0 0.4 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3158 PF11358.3 KND96379.1 - 0.21 11.0 6.9 0.044 13.2 0.8 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3158) Prominin PF05478.6 KND96379.1 - 0.29 8.6 9.9 0.86 7.0 7.2 1.3 1 1 0 1 1 1 0 Prominin Dynein_heavy PF03028.10 KND96379.1 - 0.31 8.9 7.1 0.33 8.9 4.9 1.1 1 0 0 1 1 1 0 Dynein heavy chain and region D6 of dynein motor Uds1 PF15456.1 KND96379.1 - 0.45 10.5 9.8 0.11 12.5 4.3 1.7 2 0 0 2 2 2 0 Up-regulated During Septation SlyX PF04102.7 KND96379.1 - 0.89 9.9 9.1 14 6.1 0.1 3.6 3 1 1 4 4 4 0 SlyX IncA PF04156.9 KND96379.1 - 0.92 9.0 10.0 1 8.9 2.5 2.3 1 1 1 2 2 2 0 IncA protein Syntaxin PF00804.20 KND96379.1 - 8.3 6.6 15.7 2.4 8.3 5.9 2.8 1 1 1 2 2 2 0 Syntaxin V-SNARE_C PF12352.3 KND96380.1 - 1.2e-12 47.7 1.2 1.2e-12 47.7 0.8 2.9 3 1 1 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KND96380.1 - 5.5e-08 32.4 3.6 3.3e-07 29.9 0.0 2.7 2 1 1 3 3 3 1 Sec20 DUF607 PF04678.8 KND96380.1 - 0.0025 17.7 1.3 1.1 9.1 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function, DUF607 Sigma70_r4 PF04545.11 KND96380.1 - 0.007 15.6 0.3 0.019 14.2 0.2 1.9 1 1 0 1 1 1 1 Sigma-70, region 4 DUF4407 PF14362.1 KND96380.1 - 0.015 14.2 0.8 0.019 13.9 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2408 PF10303.4 KND96380.1 - 0.019 15.0 3.9 1.1 9.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) TPR_MLP1_2 PF07926.7 KND96380.1 - 0.029 14.1 7.7 1 9.0 5.4 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Katanin_con80 PF13925.1 KND96380.1 - 0.2 11.3 1.8 0.17 11.6 0.3 1.6 2 0 0 2 2 2 0 con80 domain of Katanin FlaF PF07309.6 KND96380.1 - 0.25 11.2 3.8 8.6 6.2 0.3 2.3 2 0 0 2 2 2 0 Flagellar protein FlaF DUF1319 PF07028.6 KND96380.1 - 0.31 11.2 4.3 0.62 10.2 0.8 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1319) DUF3450 PF11932.3 KND96380.1 - 1.5 8.0 10.2 1 8.5 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF972 PF06156.8 KND96380.1 - 2 8.8 12.3 1 9.7 3.3 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 KND96380.1 - 3.1 7.4 10.6 2 8.0 2.4 2.2 1 1 1 2 2 2 0 Mnd1 family Glyco_hydro_17 PF00332.13 KND96381.1 - 1.7e-09 37.1 0.6 1.7e-09 37.1 0.4 2.4 1 1 1 2 2 2 1 Glycosyl hydrolases family 17 EF-1_beta_acid PF10587.4 KND96381.1 - 9.3 6.4 6.5 36 4.6 0.0 3.2 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region Bromodomain PF00439.20 KND96382.1 - 1.7e-32 111.1 0.2 1.6e-15 56.7 0.0 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 KND96382.1 - 5.3e-14 52.0 0.0 8.3e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 BAH domain SIR2 PF02146.12 KND96383.1 - 1.3e-40 139.0 0.0 4.4e-40 137.2 0.0 1.7 1 1 0 1 1 1 1 Sir2 family Antimicrobial_1 PF08018.6 KND96386.1 - 0.2 11.6 1.5 0.32 10.9 1.1 1.3 1 0 0 1 1 1 0 Frog antimicrobial peptide MLANA PF14991.1 KND96388.1 - 0.00018 21.4 0.6 0.00027 20.9 0.4 1.3 1 1 0 1 1 1 1 Protein melan-A WBP-1 PF11669.3 KND96388.1 - 0.0023 17.9 0.1 0.0034 17.4 0.1 1.3 1 0 0 1 1 1 1 WW domain-binding protein 1 EphA2_TM PF14575.1 KND96388.1 - 0.011 16.0 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain IncA PF04156.9 KND96388.1 - 0.017 14.6 0.0 0.019 14.5 0.0 1.1 1 0 0 1 1 1 0 IncA protein FixQ PF05545.6 KND96388.1 - 0.023 14.3 0.2 0.039 13.5 0.2 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF1049 PF06305.6 KND96388.1 - 0.025 14.0 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF4328 PF14219.1 KND96388.1 - 0.075 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) PMP22_Claudin PF00822.15 KND96388.1 - 1.1 8.8 3.8 2 8.0 2.6 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Shisa PF13908.1 KND96390.1 - 0.12 12.5 0.6 0.15 12.2 0.4 1.3 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator NOT2_3_5 PF04153.13 KND96391.1 - 6.8e-38 129.5 0.4 8.5e-38 129.2 0.3 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Metallophos_2 PF12850.2 KND96392.1 - 2.4e-16 59.9 0.0 3.4e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SDA1 PF05285.7 KND96392.1 - 2.2 7.4 16.1 2.9 7.1 11.1 1.1 1 0 0 1 1 1 0 SDA1 YqfQ PF14181.1 KND96392.1 - 2.5 8.1 5.6 3.6 7.6 3.9 1.3 1 0 0 1 1 1 0 YqfQ-like protein CDC45 PF02724.9 KND96392.1 - 2.8 5.8 11.7 3.7 5.4 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Herpes_LMP1 PF05297.6 KND96392.1 - 4.3 6.1 7.4 9.1 5.0 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Nop14 PF04147.7 KND96392.1 - 4.3 5.1 19.0 5.8 4.7 13.1 1.0 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 KND96392.1 - 7.7 5.8 16.7 11 5.2 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Choline_transpo PF04515.7 KND96393.1 - 5.6e-93 311.3 23.6 5.6e-93 311.3 16.4 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter Bac_export_2 PF01312.14 KND96393.1 - 0.34 9.7 3.0 0.26 10.1 0.2 2.1 1 1 0 2 2 2 0 FlhB HrpN YscU SpaS Family Arginase PF00491.16 KND96395.1 - 2.8e-85 285.9 0.3 3.5e-85 285.6 0.2 1.1 1 0 0 1 1 1 1 Arginase family MFS_1 PF07690.11 KND96397.1 - 3.1e-17 62.3 48.7 3.1e-17 62.3 33.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KND96397.1 - 0.0037 15.7 47.8 0.019 13.3 19.1 2.9 1 1 2 3 3 3 3 MFS/sugar transport protein LRR_4 PF12799.2 KND96398.1 - 1.3e-17 63.0 40.0 2.1e-06 27.1 0.4 8.0 5 2 3 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KND96398.1 - 9.2e-11 41.3 33.7 0.0056 16.4 2.9 6.7 4 3 1 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 KND96398.1 - 1.4e-09 36.6 36.9 1.5 9.1 0.2 11.6 8 3 4 12 12 12 4 Leucine Rich Repeat LRR_7 PF13504.1 KND96398.1 - 4.2e-08 32.1 33.8 0.44 10.9 0.2 11.2 11 0 0 11 11 11 5 Leucine rich repeat FNIP PF05725.7 KND96398.1 - 1.7e-06 27.8 31.4 0.17 11.8 0.9 7.4 6 1 1 8 8 8 3 FNIP Repeat LRR_6 PF13516.1 KND96398.1 - 1.4e-05 24.6 30.4 1.6 9.0 0.5 10.8 12 0 0 12 12 12 3 Leucine Rich repeat EIF_2_alpha PF07541.7 KND96399.1 - 1e-38 131.5 0.2 2.5e-38 130.2 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 KND96399.1 - 2.1e-14 53.3 1.2 3.6e-14 52.6 0.8 1.4 1 0 0 1 1 1 1 S1 RNA binding domain Pkinase PF00069.20 KND96400.1 - 1.2e-05 24.6 0.0 1.4e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND96400.1 - 0.0016 17.5 0.0 0.0019 17.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KND96401.1 - 3.8e-45 154.0 0.0 9.7e-45 152.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND96401.1 - 9.5e-19 67.4 0.0 1.6e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KND96401.1 - 0.01 15.5 0.1 0.025 14.3 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KND96401.1 - 0.035 12.9 0.1 0.056 12.2 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 KND96401.1 - 0.06 12.1 0.4 0.093 11.5 0.3 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 KND96401.1 - 0.075 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Rho_GDI PF02115.12 KND96403.1 - 1.1e-15 57.6 0.1 1.2e-15 57.4 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor PBP5_C PF07943.8 KND96403.1 - 0.01 15.8 1.0 0.017 15.1 0.7 1.3 1 0 0 1 1 1 0 Penicillin-binding protein 5, C-terminal domain Rib PF08428.5 KND96403.1 - 0.32 10.7 3.0 4.5 7.1 0.2 2.8 1 1 1 2 2 2 0 Rib/alpha-like repeat Memo PF01875.12 KND96406.1 - 1.7e-70 237.0 0.0 2e-70 236.8 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Adaptin_N PF01602.15 KND96407.1 - 9e-88 294.8 6.5 1.1e-87 294.5 4.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KND96407.1 - 1.4e-12 47.7 5.4 2.7e-05 24.3 0.6 5.1 3 1 2 5 5 5 3 HEAT repeats Cnd1 PF12717.2 KND96407.1 - 1e-08 35.2 7.5 1.2e-07 31.7 2.2 3.0 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KND96407.1 - 1e-06 28.3 8.3 0.036 14.1 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 KND96407.1 - 0.0014 19.0 3.9 15 6.2 0.1 5.4 5 1 0 5 5 5 1 HEAT-like repeat DUF2435 PF10363.4 KND96407.1 - 0.0081 16.0 1.8 0.35 10.7 0.1 3.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2435) Arm PF00514.18 KND96407.1 - 0.015 15.1 5.6 5.9 6.8 0.0 5.0 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat FAM220 PF15487.1 KND96407.1 - 0.088 12.1 2.8 0.17 11.2 1.9 1.4 1 0 0 1 1 1 0 FAM220 family DEAD PF00270.24 KND96408.1 - 6.1e-23 81.1 0.1 1.6e-21 76.5 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND96408.1 - 1.6e-13 50.3 0.3 9.1e-12 44.6 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 KND96408.1 - 1e-09 38.8 0.6 2.7e-09 37.4 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) Cellulase PF00150.13 KND96410.1 - 2.3e-12 46.7 5.2 3.7e-12 46.0 3.6 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 KND96410.1 - 0.065 13.6 0.0 0.2 12.1 0.0 1.9 1 0 0 1 1 1 0 Sugar-binding cellulase-like Asp PF00026.18 KND96412.1 - 5.6e-106 354.3 0.0 3e-104 348.6 0.0 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 KND96412.1 - 2.6e-10 40.4 0.0 5.8e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KND96412.1 - 3.1e-05 24.4 0.0 0.01 16.2 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KND96412.1 - 0.00033 20.2 0.0 0.0026 17.3 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal HSP70 PF00012.15 KND96414.1 - 4.5e-265 880.2 15.9 5.2e-265 880.0 11.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KND96414.1 - 1.3e-16 60.1 6.6 5.5e-15 54.7 2.6 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 KND96414.1 - 4.8e-05 23.0 0.5 0.00021 20.9 0.0 2.3 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 KND96414.1 - 0.012 14.7 2.5 0.36 9.8 0.4 3.3 2 1 0 2 2 2 0 Hydantoinase/oxoprolinase FtsA PF14450.1 KND96414.1 - 0.025 14.4 16.3 0.12 12.1 2.0 4.5 4 1 0 4 4 4 0 Cell division protein FtsA DUF615 PF04751.9 KND96414.1 - 0.036 13.6 3.7 0.11 12.1 2.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF615) DUF669 PF05037.8 KND96414.1 - 0.052 13.4 4.7 0.12 12.3 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF669) GCR1_C PF12550.3 KND96415.1 - 1.6e-21 75.9 0.1 3.3e-21 74.9 0.1 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes PAT1 PF09770.4 KND96415.1 - 0.0013 17.0 31.7 0.0016 16.8 22.0 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Spore_coat_CotO PF14153.1 KND96415.1 - 0.003 17.0 13.0 0.0046 16.4 9.0 1.3 1 0 0 1 1 1 1 Spore coat protein CotO DDHD PF02862.12 KND96415.1 - 0.0032 17.2 6.0 0.0051 16.6 4.2 1.4 1 0 0 1 1 1 1 DDHD domain SprA-related PF12118.3 KND96415.1 - 0.0067 15.7 28.1 0.0088 15.4 19.5 1.2 1 0 0 1 1 1 1 SprA-related family DUF2126 PF09899.4 KND96415.1 - 0.01 13.9 5.0 0.013 13.5 3.5 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Band_3_cyto PF07565.8 KND96415.1 - 0.016 14.7 9.9 0.026 14.0 6.8 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain RR_TM4-6 PF06459.7 KND96415.1 - 0.018 14.9 9.5 0.028 14.3 6.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4220 PF13968.1 KND96415.1 - 0.08 12.0 3.4 0.11 11.6 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Zip PF02535.17 KND96415.1 - 0.33 9.8 2.8 0.47 9.3 2.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1675 PF07897.6 KND96415.1 - 0.65 9.8 13.9 1.2 8.9 9.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) LMBR1 PF04791.11 KND96415.1 - 0.94 7.9 2.7 1.1 7.7 1.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Neur_chan_memb PF02932.11 KND96415.1 - 6.5 6.5 11.9 10 5.9 8.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 KND96415.1 - 7.4 4.1 16.7 10 3.6 11.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DHHW PF14286.1 KND96415.1 - 7.5 5.7 11.0 12 5.0 7.6 1.2 1 0 0 1 1 1 0 DHHW protein AA_permease PF00324.16 KND96417.1 - 1.6e-117 392.7 38.0 2.5e-117 392.1 26.3 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND96417.1 - 2.4e-36 125.1 37.3 3.2e-36 124.7 25.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KND96419.1 - 4.9e-90 302.1 43.3 6e-90 301.8 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND96419.1 - 3.7e-27 94.9 49.5 4.4e-27 94.6 34.3 1.1 1 0 0 1 1 1 1 Amino acid permease NOA36 PF06524.7 KND96419.1 - 3.1 6.9 4.2 5.9 6.0 2.9 1.4 1 0 0 1 1 1 0 NOA36 protein SET PF00856.23 KND96420.1 - 6.5e-12 46.0 1.4 2.9e-10 40.7 0.9 2.3 1 1 0 1 1 1 1 SET domain YHS PF04945.8 KND96420.1 - 0.02 14.7 1.5 0.02 14.7 1.1 3.1 3 0 0 3 3 3 0 YHS domain CwfJ_C_1 PF04677.10 KND96421.1 - 3.1e-26 91.4 0.0 6.1e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KND96421.1 - 1.9e-17 63.5 2.5 4.8e-17 62.2 1.7 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Ribosomal_L21e PF01157.13 KND96423.1 - 2e-37 126.9 4.1 2e-37 126.9 2.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L21e CBF PF03914.12 KND96424.1 - 5e-43 146.3 0.4 8.9e-43 145.5 0.3 1.4 1 0 0 1 1 1 1 CBF/Mak21 family Sugar_tr PF00083.19 KND96426.1 - 3.2e-75 253.4 18.6 3.9e-75 253.1 12.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND96426.1 - 1.9e-14 53.1 17.2 4.3e-13 48.7 9.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.7 KND96429.1 - 6.6e-27 93.4 1.7 1.2e-26 92.5 1.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KND96429.1 - 1.9e-23 82.3 0.0 3.2e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KND96429.1 - 0.00026 20.5 0.3 0.0006 19.4 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_18 PF12847.2 KND96429.1 - 0.032 14.8 0.0 0.058 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_3 PF01494.14 KND96429.1 - 0.036 13.1 0.0 0.048 12.7 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain Methyltransf_11 PF08241.7 KND96429.1 - 0.088 13.3 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF2105 PF09878.4 KND96430.1 - 0.021 14.3 0.2 0.045 13.3 0.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2105) TPR_2 PF07719.12 KND96431.1 - 0.0082 15.9 0.4 5.5 7.1 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KND96431.1 - 0.01 15.6 0.1 0.026 14.3 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Exo5 PF09810.4 KND96436.1 - 2e-33 116.0 3.7 5.3e-22 78.4 0.1 2.4 2 1 0 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 KND96436.1 - 0.00028 20.3 7.6 0.0031 16.9 5.3 2.3 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.12 KND96436.1 - 0.015 15.2 1.4 0.84 9.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF83 DUF1062 PF06353.7 KND96436.1 - 0.027 14.7 0.6 0.14 12.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1062) Citrate_synt PF00285.16 KND96439.1 - 5.7e-100 334.4 0.0 6.4e-100 334.3 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase PSK_trans_fac PF07704.6 KND96439.1 - 0.096 13.3 0.0 0.19 12.4 0.0 1.4 1 0 0 1 1 1 0 Rv0623-like transcription factor tRNA-synt_1 PF00133.17 KND96440.1 - 2.1e-166 554.4 0.0 3.9e-166 553.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KND96440.1 - 3.4e-25 88.5 1.9 5.9e-25 87.8 1.3 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KND96440.1 - 4.6e-24 84.7 0.1 1.8e-14 53.2 0.0 3.6 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KND96440.1 - 4.8e-06 26.0 0.0 8.7e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 KND96440.1 - 0.0067 15.5 0.0 0.94 8.5 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.9 KND96440.1 - 0.046 13.3 5.7 0.099 12.3 3.9 1.5 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS DUF4420 PF14390.1 KND96441.1 - 0.028 13.2 0.1 0.11 11.3 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4420) zf-RING_4 PF14570.1 KND96443.1 - 5.3e-16 57.9 8.0 1e-15 57.0 5.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_5 PF13893.1 KND96443.1 - 4.1e-07 29.7 0.9 7.7e-06 25.6 0.1 2.7 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KND96443.1 - 1.1e-06 28.1 0.0 0.00029 20.3 0.0 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 KND96443.1 - 0.00012 21.8 5.6 0.00054 19.7 1.3 2.6 2 1 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_3 PF13920.1 KND96443.1 - 0.0021 17.6 3.0 0.0049 16.5 2.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_6 PF14259.1 KND96443.1 - 0.0057 16.6 0.0 0.024 14.6 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 KND96443.1 - 0.043 13.4 4.7 0.1 12.2 3.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KND96443.1 - 0.15 11.9 3.7 0.36 10.6 2.6 1.7 1 0 0 1 1 1 0 Ring finger domain Pkr1 PF08636.5 KND96444.1 - 1.4e-31 108.3 6.5 1.8e-31 108.0 4.5 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF3397 PF11877.3 KND96444.1 - 0.018 15.0 3.4 0.022 14.7 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3397) DUF4131 PF13567.1 KND96444.1 - 0.025 14.0 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DcpS_C PF11969.3 KND96445.1 - 3.3e-19 69.2 0.3 8.1e-19 67.9 0.4 1.5 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 KND96445.1 - 2.1e-13 50.5 0.1 4.4e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 HIT domain zf-BED PF02892.10 KND96445.1 - 0.0025 17.5 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 BED zinc finger Yippee-Mis18 PF03226.9 KND96445.1 - 0.08 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Sugar_tr PF00083.19 KND96446.1 - 1.3e-85 287.6 22.9 1.6e-85 287.4 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND96446.1 - 1.1e-32 113.0 23.8 1.1e-32 113.0 16.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KND96446.1 - 8e-05 21.0 4.5 8e-05 21.0 3.1 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DSPc PF00782.15 KND96447.1 - 1.1e-25 89.7 0.0 2.8e-25 88.4 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KND96447.1 - 0.0035 16.7 0.0 0.0071 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Elf1 PF05129.8 KND96447.1 - 0.029 14.0 0.4 0.54 9.9 0.0 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Yippee-Mis18 PF03226.9 KND96447.1 - 0.034 14.1 0.4 0.13 12.3 0.3 2.0 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Init_tRNA_PT PF04179.7 KND96447.1 - 0.091 11.6 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Ima1_N PF09779.4 KND96447.1 - 0.16 12.4 1.5 0.65 10.5 0.3 2.1 2 0 0 2 2 2 0 Ima1 N-terminal domain RIG-I_C-RD PF11648.3 KND96447.1 - 0.32 10.8 1.8 20 5.0 1.5 2.9 3 1 0 3 3 3 0 C-terminal domain of RIG-I Apc15p PF05841.6 KND96448.1 - 6.2e-09 36.6 0.0 1.3e-08 35.5 0.0 1.5 2 0 0 2 2 2 1 Apc15p protein DUF2392 PF10288.4 KND96450.1 - 8.7e-24 83.9 0.0 1.6e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) Rick_17kDa_Anti PF05433.10 KND96451.1 - 0.0018 17.9 18.7 0.0018 17.9 12.9 1.8 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 KND96451.1 - 0.017 14.7 5.5 0.028 14.0 3.8 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 KND96451.1 - 1 9.5 12.4 2.5 8.3 8.6 1.7 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide CHCH PF06747.8 KND96452.1 - 0.00028 20.6 5.6 0.00041 20.1 3.9 1.3 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.8 KND96452.1 - 0.00071 19.5 1.5 0.0012 18.8 1.0 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) DUF1903 PF08991.5 KND96452.1 - 0.0046 17.0 2.8 0.0078 16.3 1.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) UPF0203 PF05254.7 KND96452.1 - 0.0054 16.5 3.2 0.019 14.7 2.2 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) DUF4249 PF14054.1 KND96452.1 - 0.086 12.1 1.2 0.091 12.1 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4249) Cmc1 PF08583.5 KND96452.1 - 0.14 11.9 2.8 0.97 9.2 0.7 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF4533 PF15047.1 KND96453.1 - 0.091 12.1 0.1 0.23 10.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) NDUFA12 PF05071.11 KND96456.1 - 1.1e-24 86.8 5.7 1.1e-24 86.8 3.9 1.3 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DS PF01916.12 KND96457.1 - 3e-141 469.8 0.0 3.5e-141 469.6 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Peptidase_M18 PF02127.10 KND96458.1 - 2.8e-136 454.4 0.0 3.2e-136 454.2 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 KND96458.1 - 0.0005 18.9 0.0 0.63 8.7 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase G-alpha PF00503.15 KND96461.1 - 8.8e-115 383.4 0.5 1.1e-114 383.2 0.4 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KND96461.1 - 3.4e-15 55.7 0.1 4.1e-10 39.1 0.0 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KND96461.1 - 0.0055 15.8 1.2 1.3 8.0 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 KND96461.1 - 0.0075 16.7 0.3 0.72 10.3 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 KND96461.1 - 0.03 13.8 0.1 0.064 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase PF00069.20 KND96462.1 - 5.1e-60 202.8 0.0 6.6e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND96462.1 - 3.3e-30 105.0 0.0 4.3e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND96462.1 - 0.0011 17.9 0.0 0.0017 17.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KND96462.1 - 0.0047 16.6 0.3 0.017 14.8 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KND96462.1 - 0.03 13.6 0.2 0.062 12.6 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 KND96462.1 - 0.039 13.0 0.0 0.076 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SIS PF01380.17 KND96466.1 - 1.4e-60 202.6 0.0 5e-32 110.2 0.1 2.2 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 KND96466.1 - 5.3e-23 81.3 0.0 2.4e-19 69.2 0.0 2.2 1 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KND96466.1 - 6e-19 68.3 0.0 1.2e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KND96466.1 - 3.6e-12 46.0 0.0 7.7e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KND96466.1 - 1.2e-08 34.0 0.0 1.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DUF155 PF02582.9 KND96468.1 - 1.6e-38 132.3 0.1 2.7e-38 131.6 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 AIG1 PF04548.11 KND96468.1 - 0.07 12.2 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Gb3_synth PF04572.7 KND96469.1 - 0.0047 16.6 0.3 0.0055 16.3 0.2 1.1 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Ammonium_transp PF00909.16 KND96470.1 - 6.8e-96 321.1 18.6 7.8e-96 320.9 12.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family CheY-binding PF09078.6 KND96470.1 - 0.029 14.3 0.3 0.064 13.2 0.2 1.5 1 0 0 1 1 1 0 CheY binding TPP_enzyme_N PF02776.13 KND96473.1 - 5.6e-56 188.7 0.1 1.4e-55 187.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KND96473.1 - 2.1e-50 170.2 0.1 2.5e-49 166.7 0.1 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KND96473.1 - 4.1e-36 123.7 0.2 9.8e-36 122.5 0.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.11 KND96473.1 - 0.00057 19.4 0.3 0.0018 17.8 0.0 1.9 2 0 0 2 2 2 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit DUF1788 PF08747.6 KND96473.1 - 0.02 14.7 0.0 0.078 12.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1788) POR_N PF01855.14 KND96473.1 - 0.077 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Zn_clus PF00172.13 KND96476.1 - 1.1e-09 38.0 10.1 1.8e-09 37.3 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Packaging_FI PF14000.1 KND96476.1 - 0.032 14.4 0.7 0.032 14.4 0.5 1.8 2 1 0 2 2 2 0 DNA packaging protein FI WD40_alt PF14077.1 KND96476.1 - 0.41 10.3 5.2 0.085 12.4 0.6 2.1 2 0 0 2 2 2 0 Alternative WD40 repeat motif ADH_zinc_N PF00107.21 KND96477.1 - 3.1e-26 91.4 0.6 5e-26 90.7 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KND96477.1 - 4.2e-26 90.8 0.1 1.2e-25 89.3 0.0 1.8 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain Pyr_redox PF00070.22 KND96477.1 - 5e-05 23.6 0.1 0.0085 16.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KND96477.1 - 0.00013 21.5 0.1 0.00028 20.4 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 KND96477.1 - 0.009 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.1 KND96477.1 - 0.016 16.1 0.0 0.049 14.5 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KND96477.1 - 0.025 13.7 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KND96477.1 - 0.027 13.5 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 KND96477.1 - 0.042 13.9 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KND96477.1 - 0.052 13.5 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 KND96477.1 - 0.053 13.7 0.1 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding HI0933_like PF03486.9 KND96477.1 - 0.055 11.9 0.8 0.078 11.4 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein MTS PF05175.9 KND96477.1 - 0.076 12.3 0.1 0.2 11.0 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase small domain XdhC_C PF13478.1 KND96477.1 - 0.13 12.5 0.1 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain HEXIM PF15313.1 KND96479.1 - 0.14 12.2 1.2 0.19 11.9 0.9 1.3 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein Ribosomal_L30 PF00327.15 KND96482.1 - 5.5e-14 51.4 0.4 6.9e-14 51.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e MNE1 PF13762.1 KND96486.1 - 3.2e-26 92.1 5.6 3.2e-26 92.1 3.9 3.0 4 1 0 4 4 4 1 Mitochondrial splicing apparatus component POT1 PF02765.12 KND96486.1 - 0.026 14.4 0.0 0.063 13.1 0.0 1.7 1 0 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 RPAP3_C PF13877.1 KND96486.1 - 0.47 10.4 6.0 1.2 9.1 0.2 3.8 4 1 0 4 4 4 0 Potential Monad-binding region of RPAP3 Methyltransf_23 PF13489.1 KND96487.1 - 1.4e-15 57.3 0.0 2.3e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND96487.1 - 4e-11 43.2 0.3 1.6e-09 38.1 0.1 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND96487.1 - 1.2e-09 38.5 0.1 4.7e-09 36.6 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND96487.1 - 2.1e-09 37.1 0.1 8.6e-08 31.9 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND96487.1 - 0.0005 20.3 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND96487.1 - 0.0011 19.5 1.8 0.0039 17.7 0.1 2.7 3 1 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND96487.1 - 0.0017 17.4 0.0 0.003 16.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KND96487.1 - 0.02 14.9 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 KND96487.1 - 0.052 13.5 0.0 0.13 12.2 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Lon_C PF05362.8 KND96488.1 - 5.5e-47 159.7 0.0 1e-46 158.8 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KND96488.1 - 4e-26 91.9 1.6 1.7e-25 89.8 0.2 2.4 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KND96488.1 - 5.9e-25 87.9 0.0 1.9e-24 86.3 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KND96488.1 - 1.5e-07 31.1 0.0 1.1e-06 28.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KND96488.1 - 3.5e-07 30.2 0.0 1.1e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KND96488.1 - 7.6e-06 26.0 0.1 2.9e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KND96488.1 - 2.7e-05 24.9 3.3 6.2e-05 23.7 0.1 3.3 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KND96488.1 - 5.5e-05 22.3 0.0 0.00015 20.9 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus ChlI PF13541.1 KND96488.1 - 0.00026 20.4 0.0 0.00064 19.2 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.1 KND96488.1 - 0.00095 19.3 0.1 0.028 14.5 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KND96488.1 - 0.0013 18.6 0.0 0.0042 16.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KND96488.1 - 0.0016 18.0 0.0 0.0034 17.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KND96488.1 - 0.0023 17.0 0.0 0.0051 15.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 KND96488.1 - 0.0027 17.4 0.0 0.0073 16.0 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 KND96488.1 - 0.0055 17.0 0.1 0.0055 17.0 0.0 2.7 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.10 KND96488.1 - 0.011 15.4 0.3 0.1 12.2 0.1 2.3 1 1 1 2 2 2 0 NTPase AAA_33 PF13671.1 KND96488.1 - 0.011 15.5 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KND96488.1 - 0.022 14.9 0.0 0.069 13.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 KND96488.1 - 0.023 13.8 0.0 0.046 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 UPF0079 PF02367.12 KND96488.1 - 0.024 14.2 0.0 0.063 12.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 KND96488.1 - 0.029 13.8 0.1 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain Mg_chelatase PF01078.16 KND96488.1 - 0.033 13.3 0.0 0.17 11.0 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KND96488.1 - 0.042 13.5 0.2 0.29 10.7 0.0 2.3 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.12 KND96488.1 - 0.05 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TRP PF06011.7 KND96490.1 - 1.7e-140 468.4 26.1 2.1e-140 468.1 18.1 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KND96490.1 - 1.2e-25 90.1 0.0 2e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 ML-like domain DUF615 PF04751.9 KND96491.1 - 0.088 12.4 0.1 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF615) DUF663 PF04950.7 KND96494.1 - 8.8e-98 326.9 0.0 8.8e-98 326.9 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KND96494.1 - 3e-29 100.3 0.0 2.1e-28 97.7 0.0 2.4 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 KND96494.1 - 5e-09 35.8 1.7 7.6e-06 25.4 0.0 3.0 3 0 0 3 3 2 2 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KND96494.1 - 9.1e-07 28.8 0.0 2.7e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KND96494.1 - 3.1e-06 27.4 2.1 3.4e-06 27.3 0.1 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KND96494.1 - 1.7e-05 24.8 0.0 5.4e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KND96494.1 - 1.9e-05 25.4 0.0 1.9e-05 25.4 0.0 5.3 3 1 1 4 4 3 1 AAA domain AAA_22 PF13401.1 KND96494.1 - 3e-05 24.1 0.2 0.0001 22.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KND96494.1 - 0.00014 21.5 0.2 0.0004 20.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain MobB PF03205.9 KND96494.1 - 0.00015 21.4 1.5 0.00015 21.4 1.1 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KND96494.1 - 0.00042 20.0 0.0 0.00078 19.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Miro PF08477.8 KND96494.1 - 0.00065 20.1 1.2 0.0015 19.0 0.0 2.3 2 0 0 2 2 1 1 Miro-like protein NTPase_1 PF03266.10 KND96494.1 - 0.00069 19.3 0.3 0.0016 18.1 0.2 1.6 1 0 0 1 1 1 1 NTPase PduV-EutP PF10662.4 KND96494.1 - 0.00094 18.6 0.1 0.0028 17.1 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 KND96494.1 - 0.0016 18.7 0.1 0.0016 18.7 0.0 5.1 3 1 2 6 6 5 1 AAA domain RNA_helicase PF00910.17 KND96494.1 - 0.0017 18.5 0.0 0.0054 16.8 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 KND96494.1 - 0.0019 18.1 0.0 0.0083 16.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KND96494.1 - 0.0027 17.3 0.9 0.0076 15.8 0.6 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KND96494.1 - 0.005 16.2 0.2 0.038 13.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KND96494.1 - 0.0068 16.7 1.9 0.014 15.6 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_5 PF07728.9 KND96494.1 - 0.0083 15.8 0.1 0.028 14.1 0.1 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) cobW PF02492.14 KND96494.1 - 0.016 14.6 0.8 0.056 12.8 0.5 2.0 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 KND96494.1 - 0.018 14.9 0.0 0.14 12.0 0.0 2.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KND96494.1 - 0.025 14.5 0.8 0.025 14.5 0.6 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_11 PF13086.1 KND96494.1 - 0.031 13.8 0.0 0.031 13.8 0.0 3.2 4 0 0 4 4 3 0 AAA domain Viral_helicase1 PF01443.13 KND96494.1 - 0.075 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 KND96494.1 - 0.085 12.4 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Cyclin PF08613.6 KND96497.1 - 9e-20 71.5 0.4 1.5e-19 70.9 0.3 1.3 1 0 0 1 1 1 1 Cyclin DUF4252 PF14060.1 KND96500.1 - 0.03 13.8 0.0 0.03 13.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) TSGP1 PF07771.6 KND96500.1 - 1.8 8.4 6.2 1.9 8.4 4.3 1.2 1 0 0 1 1 1 0 Tick salivary peptide group 1 DUF4606 PF15379.1 KND96501.1 - 0.065 13.3 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) ACPS PF01648.15 KND96506.1 - 6.5e-18 64.6 0.0 7.7e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily GATase PF00117.23 KND96507.1 - 1.4e-42 145.3 0.0 2.3e-42 144.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 KND96507.1 - 1.7e-40 136.6 0.1 6.4e-40 134.7 0.1 1.9 2 0 0 2 2 2 1 GMP synthase C terminal domain NAD_synthase PF02540.12 KND96507.1 - 8.9e-10 37.8 0.1 5.2e-06 25.5 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 KND96507.1 - 5.4e-08 32.5 0.3 6.2e-07 29.0 0.1 2.5 1 1 1 2 2 2 1 Peptidase C26 QueC PF06508.8 KND96507.1 - 0.00058 19.2 0.0 0.032 13.4 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.9 KND96507.1 - 0.014 14.8 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 KND96507.1 - 0.02 13.4 0.0 0.039 12.5 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase HOASN PF14515.1 KND96507.1 - 0.091 13.1 0.1 0.2 12.0 0.1 1.5 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices ATP_bind_3 PF01171.15 KND96507.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 PP-loop family DUF4658 PF15555.1 KND96508.1 - 0.14 12.0 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) WD40 PF00400.27 KND96509.1 - 2e-39 132.0 4.5 4.3e-11 42.2 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.7 KND96509.1 - 6.3e-26 90.1 0.1 1e-25 89.4 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 KND96509.1 - 1e-07 30.5 1.1 0.0012 17.1 0.3 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 N2227 PF07942.7 KND96510.1 - 4.9e-53 179.8 0.0 6.9e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein PPTA PF01239.17 KND96512.1 - 8.9e-39 129.2 19.8 8.8e-09 34.3 1.5 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_12 PF13424.1 KND96512.1 - 0.29 11.1 8.0 4.6 7.2 0.8 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KND96512.1 - 0.46 10.8 3.7 12 6.4 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KND96512.1 - 0.56 10.1 3.9 2.2 8.2 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KND96512.1 - 0.59 9.8 4.9 29 4.4 0.0 3.5 3 0 0 3 3 3 0 TPR repeat TPR_2 PF07719.12 KND96512.1 - 2.1 8.4 8.2 13 6.0 0.8 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 KND96522.1 - 4.3e-32 111.2 0.0 2.2e-31 108.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND96522.1 - 7.5e-09 35.0 0.0 1.2e-07 31.0 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KND96522.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KND96522.1 - 0.015 14.2 0.1 13 4.6 0.0 3.0 3 0 0 3 3 3 0 Kinase-like DUF4007 PF13182.1 KND96523.1 - 0.1 11.4 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4007) Sugar_tr PF00083.19 KND96524.1 - 2.2e-108 362.7 29.0 2.7e-108 362.4 20.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND96524.1 - 5.2e-27 94.4 36.6 3.1e-23 82.0 15.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KND96524.1 - 0.0035 15.8 8.2 0.0035 15.8 5.7 3.7 2 2 0 3 3 3 2 MFS/sugar transport protein Abhydrolase_6 PF12697.2 KND96525.1 - 2.4e-12 47.2 0.0 2.9e-11 43.6 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND96525.1 - 5.4e-09 35.9 0.0 2.4e-08 33.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KND96525.1 - 3.3e-06 26.9 0.0 4.4e-05 23.2 0.0 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Cutinase PF01083.17 KND96525.1 - 0.00011 22.0 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 Cutinase Abhydrolase_2 PF02230.11 KND96525.1 - 0.00079 18.9 0.0 0.0032 16.9 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 KND96525.1 - 0.0083 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.9 KND96525.1 - 0.011 15.0 0.0 0.027 13.7 0.0 1.7 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_9 PF10081.4 KND96525.1 - 0.015 13.9 0.0 0.059 12.0 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta-hydrolase family LCAT PF02450.10 KND96525.1 - 0.046 12.6 0.0 0.079 11.9 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase MFS_1 PF07690.11 KND96526.1 - 3.2e-40 137.9 20.4 3.2e-40 137.9 14.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily SpoVAB PF13782.1 KND96526.1 - 0.0023 17.8 0.7 0.006 16.5 0.5 1.7 1 0 0 1 1 1 1 Stage V sporulation protein AB MFS_1 PF07690.11 KND96528.1 - 6.5e-35 120.4 26.4 8.6e-35 120.0 16.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND96528.1 - 2.7e-10 39.4 14.3 4.8e-10 38.6 9.9 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter SpoVAB PF13782.1 KND96528.1 - 0.059 13.3 0.6 0.059 13.3 0.4 2.3 2 0 0 2 2 2 0 Stage V sporulation protein AB MFS_1 PF07690.11 KND96529.1 - 2.7e-37 128.3 18.9 2.7e-37 128.3 13.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MtrG PF04210.8 KND96533.1 - 0.029 14.0 0.4 0.032 13.8 0.3 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF2803 PF10972.3 KND96534.1 - 0.013 15.0 0.4 0.015 14.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2803) Uds1 PF15456.1 KND96534.1 - 0.027 14.4 5.5 0.038 13.9 3.8 1.3 1 0 0 1 1 1 0 Up-regulated During Septation DUF3027 PF11228.3 KND96534.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) FlaG PF03646.10 KND96534.1 - 0.78 9.9 4.3 24 5.1 0.0 2.9 2 1 1 3 3 3 0 FlaG protein YL1 PF05764.8 KND96534.1 - 5.5 6.5 10.4 6.7 6.2 7.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein EcsB PF05975.7 KND96539.1 - 0.25 9.7 4.3 0.047 12.1 0.3 1.6 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB zf-CCHC PF00098.18 KND96541.1 - 0.063 13.2 2.3 0.15 12.0 1.6 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF2235 PF09994.4 KND96545.1 - 3.7e-67 226.5 0.0 4.9e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Peptidase_S9 PF00326.16 KND96545.1 - 0.11 11.7 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family UCR_TM PF02921.9 KND96546.1 - 3.2e-21 75.3 0.4 5.8e-21 74.4 0.3 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 KND96546.1 - 1.6e-18 66.0 0.0 2.4e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain HECT PF00632.20 KND96547.1 - 1.1e-77 261.3 0.0 2.4e-77 260.2 0.0 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Nucleopor_Nup85 PF07575.8 KND96550.1 - 9e-61 205.7 4.8 1.6e-60 204.9 3.3 1.3 1 0 0 1 1 1 1 Nup85 Nucleoporin Ribosomal_L7Ae PF01248.21 KND96552.1 - 2.6e-26 90.9 0.1 3.1e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KND96552.1 - 0.0012 18.6 0.0 0.0013 18.5 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 KND96552.1 - 0.0053 16.4 0.0 0.0071 16.0 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain Urb2 PF10441.4 KND96553.1 - 6.1e-51 173.1 3.5 2.6e-50 171.1 2.4 2.2 1 0 0 1 1 1 1 Urb2/Npa2 family Voltage_CLC PF00654.15 KND96554.1 - 1.4e-83 280.8 25.1 1.4e-83 280.8 17.4 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KND96554.1 - 2.7e-14 52.6 0.9 7.7e-06 25.6 0.1 2.7 2 0 0 2 2 2 2 CBS domain AATase PF07247.7 KND96555.1 - 3.7e-58 197.2 0.0 8e-58 196.1 0.0 1.4 1 1 0 1 1 1 1 Alcohol acetyltransferase Syntaxin_2 PF14523.1 KND96556.1 - 4e-17 62.1 1.9 4e-17 62.1 1.4 2.8 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 KND96556.1 - 6.8e-17 60.9 4.4 2e-16 59.4 3.0 1.9 1 0 0 1 1 1 1 SNARE domain Synaptobrevin PF00957.16 KND96556.1 - 0.00013 21.5 0.6 0.00013 21.5 0.4 2.5 2 0 0 2 2 2 1 Synaptobrevin MCPsignal PF00015.16 KND96556.1 - 0.0044 16.5 1.8 0.0044 16.5 1.2 1.8 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain LAMTOR PF15454.1 KND96556.1 - 0.019 15.2 5.7 4.7 7.5 2.7 2.8 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Corona_S2 PF01601.11 KND96556.1 - 0.073 11.1 1.5 0.084 10.9 0.1 1.8 1 1 1 2 2 2 0 Coronavirus S2 glycoprotein DUF912 PF06024.7 KND96556.1 - 0.094 12.7 2.4 0.28 11.2 0.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Amnionless PF14828.1 KND96556.1 - 0.23 9.8 5.4 0.35 9.2 3.7 1.2 1 0 0 1 1 1 0 Amnionless T2SF PF00482.18 KND96556.1 - 0.38 10.6 4.4 2.6 7.9 0.9 2.6 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF2839 PF10999.3 KND96556.1 - 0.83 9.7 0.0 0.83 9.7 0.0 3.0 4 0 0 4 4 3 0 Protein of unknown function (DUF2839) Uds1 PF15456.1 KND96556.1 - 1.5 8.7 9.2 1.1 9.2 3.1 2.7 2 1 0 2 2 2 0 Up-regulated During Septation Mnd1 PF03962.10 KND96556.1 - 2.8 7.5 15.6 1.4 8.5 0.6 2.2 2 0 0 2 2 2 0 Mnd1 family Laminin_II PF06009.7 KND96556.1 - 6.7 6.4 11.6 1 9.0 3.3 2.3 2 0 0 2 2 2 0 Laminin Domain II DNA_pol_B PF00136.16 KND96559.1 - 9.1e-112 374.1 7.6 1.3e-111 373.6 5.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 KND96559.1 - 5.2e-65 218.3 2.6 1.1e-64 217.2 1.8 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 KND96559.1 - 3e-34 118.3 0.0 6e-34 117.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 KND96559.1 - 9.4e-23 79.8 9.8 9.4e-23 79.8 6.8 2.4 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal Glyoxalase PF00903.20 KND96560.1 - 1.6e-12 47.5 0.0 2.7e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KND96560.1 - 4.1e-06 26.7 0.0 0.00042 20.3 0.0 3.0 3 0 0 3 3 3 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.1 KND96560.1 - 0.0031 17.4 0.0 2.5 8.0 0.0 2.5 2 0 0 2 2 2 2 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal SNF5 PF04855.7 KND96561.1 - 1.1e-60 205.0 0.5 5.5e-38 130.8 0.0 2.6 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 UPF0242 PF06785.6 KND96561.1 - 8.8 4.8 8.8 12 4.4 1.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) Cys_Met_Meta_PP PF01053.15 KND96562.1 - 3e-68 229.8 0.0 5.5e-68 229.0 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Uricase PF01014.13 KND96563.1 - 2e-71 238.4 1.8 1.2e-35 122.5 0.8 2.0 2 0 0 2 2 2 2 Uricase RNB PF00773.14 KND96565.1 - 1.3e-59 202.1 0.1 1.3e-59 202.1 0.1 2.3 3 1 0 3 3 3 1 RNB domain DUF221 PF02714.10 KND96568.1 - 6.3e-110 367.0 19.3 6.3e-110 367.0 13.4 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KND96568.1 - 1.3e-40 138.5 0.8 1.3e-40 138.5 0.6 2.6 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KND96568.1 - 5.9e-23 80.5 0.1 1.4e-22 79.3 0.1 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KND96568.1 - 5.1e-15 55.7 1.9 1.2e-14 54.5 1.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Pyrophosphatase PF00719.14 KND96569.1 - 3.9e-50 169.3 0.0 5.2e-50 168.9 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase PARG_cat PF05028.9 KND96569.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Poly (ADP-ribose) glycohydrolase (PARG) Nup188 PF10487.4 KND96570.1 - 1.5e-166 555.9 28.0 2.2e-166 555.4 19.4 1.2 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 GHMP_kinases_N PF00288.21 KND96571.1 - 4e-18 65.2 3.1 1.8e-17 63.1 0.2 2.7 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KND96571.1 - 3.6e-07 30.2 0.1 1.3e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 KND96571.1 - 0.0044 16.2 0.1 0.012 14.8 0.0 1.8 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Mtc PF03820.12 KND96572.1 - 5e-115 383.3 0.2 5.6e-115 383.2 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier ORF11CD3 PF10549.4 KND96573.1 - 0.18 11.5 0.5 0.18 11.5 0.3 1.0 1 0 0 1 1 1 0 ORF11CD3 domain SKG6 PF08693.5 KND96574.1 - 0.00012 21.2 0.5 0.00025 20.3 0.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.15 KND96574.1 - 0.0015 18.0 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain EphA2_TM PF14575.1 KND96574.1 - 0.073 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Form-deh_trans PF09163.6 KND96574.1 - 0.083 12.3 0.0 0.17 11.4 0.0 1.6 1 1 0 1 1 1 0 Formate dehydrogenase N, transmembrane DUF872 PF05915.7 KND96574.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) TMEM51 PF15345.1 KND96574.1 - 0.15 11.7 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Beta-APP PF03494.8 KND96574.1 - 1.4 8.4 5.2 2.6 7.5 3.6 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) DUF2408 PF10303.4 KND96575.1 - 3e-54 182.7 16.2 2.4e-36 124.8 1.8 5.0 2 2 2 4 4 4 3 Protein of unknown function (DUF2408) YkyA PF10368.4 KND96575.1 - 0.00037 19.8 3.0 0.00037 19.8 2.1 2.2 2 0 0 2 2 2 1 Putative cell-wall binding lipoprotein DUF479 PF04336.7 KND96575.1 - 0.17 12.0 1.0 22 5.1 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function, DUF479 MerR-DNA-bind PF09278.6 KND96575.1 - 1.6 9.1 5.4 0.71 10.3 0.8 2.6 2 0 0 2 2 2 0 MerR, DNA binding Med9 PF07544.8 KND96575.1 - 1.7 8.4 9.1 3.6 7.3 0.2 3.8 4 1 1 5 5 5 0 RNA polymerase II transcription mediator complex subunit 9 Cut8_C PF08559.5 KND96576.1 - 7.6e-40 136.0 2.6 1.5e-39 135.1 0.6 2.4 3 1 0 3 3 3 1 Cut8 six-helix bundle Cut8_M PF14483.1 KND96576.1 - 1.4e-12 47.1 0.9 1.4e-12 47.1 0.6 1.8 2 0 0 2 2 2 1 Cut8 dimerisation domain XPC-binding PF09280.6 KND96576.1 - 0.041 13.3 0.0 0.092 12.2 0.0 1.5 1 0 0 1 1 1 0 XPC-binding domain BING4CT PF08149.6 KND96577.1 - 8.6e-39 130.9 0.0 6.1e-36 121.7 0.0 3.0 2 0 0 2 2 2 2 BING4CT (NUC141) domain WD40 PF00400.27 KND96577.1 - 9.9e-08 31.5 0.0 2.8e-05 23.8 0.0 4.2 5 0 0 5 5 5 1 WD domain, G-beta repeat DHO_dh PF01180.16 KND96578.1 - 1.8e-94 316.0 0.0 2.2e-94 315.7 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase DASH_Dam1 PF08653.5 KND96579.1 - 6e-13 48.3 0.6 1.2e-12 47.3 0.4 1.6 1 0 0 1 1 1 1 DASH complex subunit Dam1 TSC22 PF01166.13 KND96579.1 - 0.047 13.6 0.3 0.083 12.8 0.2 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family Nnf1 PF03980.9 KND96579.1 - 0.076 13.0 0.1 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Nnf1 DivIC PF04977.10 KND96579.1 - 0.12 11.8 0.9 0.2 11.1 0.6 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF1192 PF06698.6 KND96579.1 - 0.14 11.9 2.4 0.34 10.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Translat_reg PF01818.12 KND96580.1 - 0.021 14.3 0.4 0.022 14.2 0.3 1.0 1 0 0 1 1 1 0 Bacteriophage translational regulator Proteasom_PSMB PF10508.4 KND96580.1 - 0.026 12.8 0.6 0.026 12.8 0.4 1.0 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit tRNA_bind_2 PF13725.1 KND96580.1 - 0.1 12.7 0.3 0.11 12.6 0.2 1.1 1 0 0 1 1 1 0 Possible tRNA binding domain DUF1863 PF08937.6 KND96580.1 - 0.1 12.6 0.2 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) UPF0181 PF03701.9 KND96580.1 - 4.5 6.6 5.9 2.5 7.4 2.0 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0181) GET2 PF08690.5 KND96581.1 - 3.1e-73 246.6 0.1 3.6e-73 246.4 0.0 1.0 1 0 0 1 1 1 1 GET complex subunit GET2 SGS PF05002.10 KND96581.1 - 0.34 10.6 1.5 17 5.2 0.0 2.7 2 1 1 3 3 3 0 SGS domain SURF1 PF02104.10 KND96582.1 - 2.5e-57 194.1 0.0 3.7e-57 193.5 0.0 1.3 1 0 0 1 1 1 1 SURF1 family Nop PF01798.13 KND96583.1 - 3.5e-60 201.6 0.1 3.5e-60 201.6 0.1 1.8 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 KND96583.1 - 3.8e-27 93.8 0.1 7.9e-27 92.8 0.1 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KND96583.1 - 2.5e-23 81.9 0.9 2.5e-23 81.9 0.6 2.7 2 1 0 2 2 2 1 NOP5NT (NUC127) domain DDHD PF02862.12 KND96583.1 - 0.72 9.6 10.0 1.2 8.8 7.0 1.4 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 KND96583.1 - 1.6 8.5 15.5 2.9 7.7 10.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNase_H2-Ydr279 PF09468.5 KND96583.1 - 3 6.9 19.7 6.7 5.8 13.6 1.6 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Herpes_DNAp_acc PF04929.7 KND96583.1 - 4.5 6.1 12.2 6 5.7 8.5 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor CT47 PF15623.1 KND96583.1 - 8.5 6.0 17.0 12 5.5 11.8 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 Fungal_trans_2 PF11951.3 KND96585.1 - 1.2e-77 261.1 0.1 1.7e-77 260.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND96585.1 - 3.2e-07 30.1 9.6 5.8e-07 29.3 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UQ_con PF00179.21 KND96586.1 - 1.9e-42 144.0 0.1 2.1e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KND96586.1 - 6e-05 22.8 0.0 6.8e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KND96586.1 - 0.00037 20.3 0.0 0.0005 19.9 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KND96586.1 - 0.071 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain Bromodomain PF00439.20 KND96587.1 - 5e-19 68.0 0.1 1.5e-18 66.4 0.1 1.9 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 KND96587.1 - 2.4e-10 39.9 0.1 1.8e-09 37.1 0.0 2.4 2 0 0 2 2 2 1 Bromodomain associated RCC1 PF00415.13 KND96588.1 - 2.3e-14 53.3 0.5 0.0002 21.5 0.0 5.3 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 KND96588.1 - 3.1e-10 40.0 0.6 0.00067 19.6 0.0 3.2 2 1 1 3 3 3 2 BTB/POZ domain RCC1_2 PF13540.1 KND96588.1 - 2.6e-09 36.4 1.6 0.0004 19.9 0.2 4.3 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 KND96588.1 - 8.2e-05 23.0 0.2 0.6 10.7 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND96588.1 - 0.0047 17.0 0.3 2.1 8.8 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 KND96588.1 - 0.044 14.0 0.4 0.72 10.1 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.25 KND96588.1 - 0.071 12.9 0.3 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat AAA_26 PF13500.1 KND96588.1 - 0.1 12.1 0.1 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DNA_binding_1 PF01035.15 KND96589.1 - 2.1e-20 72.2 0.1 7.5e-20 70.4 0.0 1.7 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain ubiquitin PF00240.18 KND96591.1 - 0.013 14.8 0.0 12 5.3 0.0 3.4 3 0 0 3 3 3 0 Ubiquitin family zf-Mss51 PF13824.1 KND96593.1 - 1.8e-18 66.1 2.1 3.1e-18 65.3 1.5 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 PRKCSH PF07915.8 KND96594.1 - 2.5e-11 44.2 0.4 7.9e-11 42.6 0.3 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ACCA PF03255.9 KND96595.1 - 0.0055 16.2 1.6 0.007 15.9 1.1 1.1 1 0 0 1 1 1 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit AKNA PF12443.3 KND96595.1 - 0.018 15.0 1.1 0.023 14.7 0.8 1.1 1 0 0 1 1 1 0 AT-hook-containing transcription factor COG5 PF10392.4 KND96595.1 - 0.025 14.5 1.0 0.032 14.1 0.7 1.1 1 0 0 1 1 1 0 Golgi transport complex subunit 5 AF0941-like PF14591.1 KND96595.1 - 0.032 14.2 2.3 0.039 14.0 1.6 1.1 1 0 0 1 1 1 0 AF0941-like XH PF03469.9 KND96595.1 - 0.047 13.3 1.5 0.055 13.1 1.0 1.1 1 0 0 1 1 1 0 XH domain LXG PF04740.7 KND96595.1 - 0.054 13.2 2.3 0.062 13.0 1.6 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily ApoO PF09769.4 KND96595.1 - 0.059 13.0 0.2 0.062 13.0 0.1 1.1 1 0 0 1 1 1 0 Apolipoprotein O HSP70 PF00012.15 KND96595.1 - 0.059 11.2 3.8 0.065 11.1 2.6 1.0 1 0 0 1 1 1 0 Hsp70 protein Pkip-1 PF06878.6 KND96595.1 - 0.064 13.1 1.8 0.078 12.8 1.2 1.1 1 0 0 1 1 1 0 Pkip-1 protein phiKZ_IP PF12699.2 KND96595.1 - 0.065 12.1 2.5 0.11 11.3 1.4 1.4 1 1 1 2 2 2 0 phiKZ-like phage internal head proteins GP41 PF00517.12 KND96595.1 - 0.073 12.6 0.2 0.085 12.4 0.1 1.1 1 0 0 1 1 1 0 Retroviral envelope protein GLTSCR1 PF15249.1 KND96595.1 - 0.11 12.6 1.3 0.13 12.3 0.9 1.2 1 0 0 1 1 1 0 Glioma tumor suppressor candidate region ING PF12998.2 KND96595.1 - 0.12 12.6 3.6 0.16 12.2 2.5 1.2 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Fzo_mitofusin PF04799.8 KND96595.1 - 0.2 11.0 1.5 0.24 10.7 1.0 1.1 1 0 0 1 1 1 0 fzo-like conserved region DUF883 PF05957.8 KND96595.1 - 0.21 11.9 1.2 0.28 11.6 0.5 1.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Prefoldin PF02996.12 KND96595.1 - 0.59 9.7 5.0 1.4 8.5 1.5 2.0 1 1 1 2 2 2 0 Prefoldin subunit DUF536 PF04394.9 KND96595.1 - 1.5 8.6 5.8 6.6 6.5 4.0 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF536 Vpu PF00558.14 KND96595.1 - 4 7.0 8.6 2.5 7.7 1.4 2.1 1 1 1 2 2 2 0 Vpu protein DUF382 PF04037.8 KND96596.1 - 3.9e-49 165.7 3.4 6.7e-49 164.9 0.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 KND96596.1 - 2.7e-14 52.2 0.0 5e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 PSP DUF1053 PF06327.9 KND96596.1 - 1.6 9.0 18.3 0.22 11.8 2.4 3.6 2 1 0 3 3 3 0 Domain of Unknown Function (DUF1053) Zn_clus PF00172.13 KND96597.1 - 4.5e-05 23.2 8.0 7.7e-05 22.5 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Molybdopterin PF00384.17 KND96598.1 - 1.2e-67 228.5 0.0 2.2e-65 221.1 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 KND96598.1 - 5.7e-20 70.9 0.4 1.8e-19 69.3 0.3 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 KND96598.1 - 4.8e-17 60.9 0.3 1.3e-16 59.5 0.2 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 KND96598.1 - 1.1e-13 51.1 0.0 3.3e-13 49.5 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 KND96598.1 - 1.5e-07 31.0 3.8 1.8e-07 30.8 0.5 2.5 1 1 1 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 KND96598.1 - 0.0019 17.9 0.0 0.06 13.1 0.0 2.8 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.22 KND96598.1 - 0.094 12.3 1.0 3 7.6 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.6 KND96598.1 - 0.25 11.1 2.4 3.4 7.5 1.6 2.5 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4_18 PF13746.1 KND96598.1 - 0.26 11.7 3.2 0.72 10.3 2.2 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain FAM209 PF15206.1 KND96600.1 - 0.052 13.3 0.7 0.085 12.6 0.4 1.5 1 1 0 1 1 1 0 FAM209 family DUF3400 PF11880.3 KND96600.1 - 0.093 11.9 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) Dermcidin PF15291.1 KND96600.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide DUF4163 PF13739.1 KND96600.1 - 0.71 10.6 3.5 23 5.8 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4163) DUF2034 PF10356.4 KND96601.1 - 5.9e-44 149.4 0.0 7e-44 149.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 KND96601.1 - 2.4e-05 24.0 0.0 0.011 15.5 0.0 2.3 2 0 0 2 2 2 2 Restriction endonuclease Glyco_hydro_18 PF00704.23 KND96602.1 - 1.4e-21 77.3 8.0 1.8e-20 73.6 5.5 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 NAD_binding_5 PF07994.7 KND96604.1 - 9.6e-114 379.8 0.2 1.1e-113 379.6 0.2 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 KND96604.1 - 9.3e-44 147.8 0.6 9.3e-44 147.8 0.4 1.8 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase AMP-binding PF00501.23 KND96605.1 - 1.9e-78 263.7 0.0 2.5e-78 263.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KND96605.1 - 0.012 16.5 0.1 0.043 14.7 0.0 2.0 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Asparaginase PF00710.15 KND96606.1 - 1.8e-75 253.7 0.0 2e-75 253.5 0.0 1.0 1 0 0 1 1 1 1 Asparaginase COX6B PF02297.12 KND96608.1 - 1.1e-21 76.6 5.7 1.3e-21 76.4 4.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 KND96608.1 - 0.12 12.4 0.9 0.57 10.2 0.6 2.1 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 TRAPPC9-Trs120 PF08626.6 KND96609.1 - 5.9e-261 868.5 13.0 6.7e-261 868.3 9.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Proteasome PF00227.21 KND96610.1 - 3.9e-45 153.4 0.0 4.9e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 KND96610.1 - 2.4e-14 52.3 0.3 5e-14 51.2 0.2 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal MCH PF02289.11 KND96610.1 - 0.069 12.1 0.0 0.096 11.7 0.0 1.2 1 0 0 1 1 1 0 Cyclohydrolase (MCH) Aha1_N PF09229.6 KND96611.1 - 4.9e-37 126.8 0.1 7.5e-37 126.2 0.1 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KND96611.1 - 1.8e-15 57.1 0.0 2.9e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DUF2217 PF10265.4 KND96611.1 - 0.0019 17.0 0.7 0.0025 16.6 0.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2217) Drc1-Sld2 PF11719.3 KND96611.1 - 0.34 9.9 5.4 6.6 5.7 3.6 2.1 1 1 0 1 1 1 0 DNA replication and checkpoint protein ADH_zinc_N PF00107.21 KND96612.1 - 5.4e-21 74.4 0.3 9.6e-21 73.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KND96612.1 - 0.0062 17.4 0.0 0.013 16.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KND96612.1 - 0.0093 15.3 0.1 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 KND96612.1 - 0.0095 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Gp_dh_N PF00044.19 KND96612.1 - 0.025 14.5 0.6 3 7.7 0.2 2.4 2 1 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain HycI PF01750.13 KND96612.1 - 0.041 13.4 0.1 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase maturation protease Pyr_redox_3 PF13738.1 KND96612.1 - 0.044 13.8 0.1 0.086 12.8 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KND96612.1 - 0.046 13.9 0.2 0.08 13.2 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Iso_dh PF00180.15 KND96613.1 - 6.6e-99 331.1 0.1 7.5e-99 330.9 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4591 PF15261.1 KND96613.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4591) Formyl_trans_N PF00551.14 KND96614.1 - 2e-43 148.0 1.3 1.7e-42 144.9 0.9 1.9 1 1 0 1 1 1 1 Formyl transferase GTP_EFTU PF00009.22 KND96615.1 - 4.6e-64 215.3 0.5 6.4e-64 214.8 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KND96615.1 - 4e-37 126.4 0.0 1.1e-36 124.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 KND96615.1 - 1.1e-20 73.2 0.0 2.6e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KND96615.1 - 4.7e-13 48.7 0.0 1.6e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KND96615.1 - 7.8e-13 48.3 0.1 2.7e-12 46.6 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KND96615.1 - 1.3e-05 25.1 0.3 3.1e-05 23.8 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 KND96615.1 - 0.0082 15.6 1.0 0.08 12.4 0.6 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Cu_amine_oxid PF01179.15 KND96618.1 - 5.5e-158 526.0 0.0 6.7e-158 525.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KND96618.1 - 7.9e-24 83.6 0.0 1.9e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KND96618.1 - 4.4e-19 68.3 0.1 9.9e-19 67.2 0.1 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain RNA_Me_trans PF04252.8 KND96619.1 - 2.9e-60 203.0 0.1 3.6e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase DDHD PF02862.12 KND96620.1 - 8e-55 186.1 1.6 4.6e-54 183.6 0.0 2.5 3 0 0 3 3 3 1 DDHD domain WWE PF02825.15 KND96620.1 - 2.5e-05 23.6 0.1 0.0012 18.1 0.0 2.5 2 0 0 2 2 2 1 WWE domain Lipase_3 PF01764.20 KND96620.1 - 0.032 13.8 0.0 0.086 12.4 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.2 KND96620.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1689 PF07954.6 KND96621.1 - 2.9e-21 75.8 0.2 4.1e-21 75.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) tRNA-synt_2b PF00587.20 KND96622.1 - 2e-47 161.0 0.3 3.7e-47 160.1 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KND96622.1 - 1.6e-17 63.2 1.0 1.6e-17 63.2 0.7 2.2 2 0 0 2 2 2 1 Anticodon binding domain tRNA_SAD PF07973.9 KND96622.1 - 8.7e-13 47.9 0.0 2.3e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 KND96622.1 - 4.6e-12 45.6 0.0 1.3e-11 44.1 0.0 1.8 2 0 0 2 2 2 1 TGS domain Ribosomal_L14 PF00238.14 KND96623.1 - 1.6e-47 160.2 0.2 1.8e-47 160.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_S17 PF00366.15 KND96623.1 - 0.024 14.6 0.2 0.066 13.2 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein S17 UPF0029 PF01205.14 KND96624.1 - 4.2e-28 97.2 0.0 4.8e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 FAD-oxidase_C PF02913.14 KND96625.1 - 3.2e-55 187.1 0.0 5.1e-55 186.4 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KND96625.1 - 1.8e-35 121.4 0.1 3.3e-35 120.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain AMP-binding PF00501.23 KND96626.1 - 2e-72 243.9 0.0 5e-72 242.5 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme Flavin_Reduct PF01613.13 KND96627.1 - 7.5e-19 68.0 0.0 1.2e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Microvir_lysis PF04517.7 KND96627.1 - 0.33 10.7 1.8 16 5.3 0.1 2.3 2 0 0 2 2 2 0 Microvirus lysis protein (E), C terminus DHquinase_II PF01220.14 KND96628.1 - 1.2e-57 193.1 0.2 1.4e-57 192.9 0.2 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Peripla_BP_1 PF00532.16 KND96628.1 - 0.017 14.3 0.1 0.022 13.9 0.1 1.1 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family PAC2 PF09754.4 KND96629.1 - 1.1e-32 113.7 0.9 6.1e-31 107.9 0.6 2.0 1 1 0 1 1 1 1 PAC2 family DHH PF01368.15 KND96629.1 - 0.079 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 DHH family AFT PF08731.6 KND96630.1 - 1.3e-22 80.0 1.1 1.5e-10 41.2 0.2 2.3 1 1 1 2 2 2 2 Transcription factor AFT DBD_Tnp_Mut PF03108.10 KND96630.1 - 2.5e-05 23.7 0.1 3.9e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 MuDR family transposase Ribosomal_L12 PF00542.14 KND96631.1 - 4.6e-18 64.9 8.2 4.6e-18 64.9 5.7 2.6 3 0 0 3 3 3 1 Ribosomal protein L7/L12 C-terminal domain Pkinase PF00069.20 KND96632.1 - 1.7e-69 233.8 0.0 2.2e-69 233.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND96632.1 - 1.2e-38 132.7 0.0 1.8e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND96632.1 - 6.2e-05 22.1 0.0 0.00012 21.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KND96632.1 - 0.062 12.6 0.2 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 KND96632.1 - 0.14 10.9 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 TFIIA PF03153.8 KND96632.1 - 0.18 11.6 6.8 0.23 11.3 4.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 KND96632.1 - 6.7 4.8 23.3 8.3 4.5 16.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Nramp PF01566.13 KND96633.1 - 1.1e-84 284.2 14.5 1.9e-84 283.5 10.0 1.3 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein ESSS PF10183.4 KND96633.1 - 0.15 12.4 1.0 2 8.8 0.0 2.4 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) zf-C2H2_4 PF13894.1 KND96635.1 - 0.041 14.2 18.7 0.44 10.9 0.5 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KND96635.1 - 0.86 10.0 25.9 0.13 12.6 0.8 4.4 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-DBF PF07535.7 KND96635.1 - 1.1 9.0 4.5 1.4 8.6 1.6 2.4 2 1 0 2 2 2 0 DBF zinc finger zf-C2H2_2 PF12756.2 KND96635.1 - 1.5 8.9 7.7 0.16 12.1 1.2 2.3 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) HAD PF12710.2 KND96636.1 - 8.2e-17 61.9 0.0 1.2e-16 61.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KND96636.1 - 6.9e-06 26.4 0.0 2.7e-05 24.4 0.0 1.9 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KND96636.1 - 2.5e-05 23.5 0.0 3.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.7 KND96636.1 - 0.0014 17.9 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) SpoU_sub_bind PF08032.7 KND96636.1 - 0.0055 16.8 0.0 0.12 12.5 0.0 2.5 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding Hydrolase PF00702.21 KND96636.1 - 0.03 14.7 0.0 0.22 11.8 0.0 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase SpoU_methylas_C PF12105.3 KND96636.1 - 0.12 11.9 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal Pkinase PF00069.20 KND96637.1 - 7.7e-71 238.2 0.2 1.8e-70 237.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND96637.1 - 7.5e-35 120.2 0.1 3e-34 118.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND96637.1 - 4.2e-06 25.9 0.5 0.066 12.1 0.0 3.2 3 0 0 3 3 3 3 Kinase-like SNF2_N PF00176.18 KND96638.1 - 5.3e-34 117.3 0.3 3.6e-32 111.3 0.0 3.1 2 1 0 2 2 2 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 KND96638.1 - 2.4e-09 36.8 8.0 4.8e-09 35.9 5.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KND96638.1 - 3.5e-09 36.1 5.8 8.3e-09 34.9 4.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KND96638.1 - 8.7e-09 34.8 9.6 1.9e-08 33.8 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KND96638.1 - 4.1e-08 33.1 10.4 9.9e-08 31.8 7.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KND96638.1 - 7.9e-07 29.1 4.5 2.2e-06 27.6 3.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KND96638.1 - 2.2e-06 27.2 8.2 4.7e-06 26.2 5.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.1 KND96638.1 - 0.0045 16.4 3.8 0.011 15.2 2.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 KND96638.1 - 0.008 15.8 5.3 0.037 13.7 3.8 2.2 1 1 1 2 2 2 1 RING-type zinc-finger Helicase_C PF00271.26 KND96638.1 - 0.024 14.4 0.0 0.069 13.0 0.0 1.8 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-RING_4 PF14570.1 KND96638.1 - 0.056 13.0 7.3 0.026 14.0 2.7 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 KND96638.1 - 0.11 12.3 1.8 0.25 11.2 1.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KND96638.1 - 0.57 10.1 9.0 1.5 8.7 6.2 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KND96638.1 - 0.74 9.6 3.8 1.9 8.3 2.7 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein tRNA_anti-codon PF01336.20 KND96639.1 - 1e-08 34.9 1.5 1.5e-08 34.3 0.2 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain RPA_C PF08784.6 KND96639.1 - 5.2e-07 30.0 0.4 1.6e-06 28.4 0.0 2.0 2 1 0 2 2 2 1 Replication protein A C terminal Rrf2 PF02082.15 KND96639.1 - 0.14 12.3 0.0 15 5.7 0.0 2.7 3 0 0 3 3 3 0 Transcriptional regulator MFS_1 PF07690.11 KND96640.1 - 1e-36 126.4 35.2 1e-36 126.4 24.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND96640.1 - 1.6e-09 36.8 32.1 1.1e-08 34.1 22.2 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter Csm1 PF12539.3 KND96642.1 - 3.8e-26 91.3 1.9 4.9e-26 91.0 0.3 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 zf-LYAR PF08790.6 KND96643.1 - 7.6e-16 57.5 5.3 7.6e-16 57.5 3.7 2.0 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-TRAF PF02176.13 KND96643.1 - 0.0066 16.8 2.3 0.011 16.0 1.6 1.4 1 0 0 1 1 1 1 TRAF-type zinc finger RNHCP PF12647.2 KND96643.1 - 0.24 11.2 5.1 0.27 11.0 0.3 2.3 1 1 1 2 2 2 0 RNHCP domain LIM PF00412.17 KND96643.1 - 0.35 10.9 5.1 1.5 8.9 3.5 2.0 1 1 0 1 1 1 0 LIM domain COX16 PF14138.1 KND96645.1 - 2.4e-27 94.9 0.9 4e-27 94.2 0.6 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 WD40 PF00400.27 KND96646.1 - 3.6e-68 223.1 17.6 1.5e-11 43.6 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 KND96646.1 - 1.6e-30 105.1 11.3 3.4e-30 104.0 7.8 1.6 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 KND96646.1 - 5.2e-05 21.5 4.6 0.67 8.0 0.0 4.3 1 1 3 4 4 4 3 Nucleoporin Nup120/160 GHMP_kinases_C PF08544.8 KND96648.1 - 0.0058 16.8 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal Enterotoxin_a PF01375.12 KND96648.1 - 0.075 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Heat-labile enterotoxin alpha chain CDP-OH_P_transf PF01066.16 KND96650.1 - 6.7e-15 55.2 2.8 6.7e-15 55.2 1.9 1.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Pex24p PF06398.6 KND96652.1 - 0.044 12.5 3.6 0.055 12.2 2.5 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin bZIP_1 PF00170.16 KND96654.1 - 3e-11 43.1 14.0 4.9e-11 42.4 9.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KND96654.1 - 0.00047 19.9 13.2 0.001 18.8 9.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KND96654.1 - 0.005 17.1 7.9 0.005 17.1 5.5 2.0 2 0 0 2 2 2 1 bZIP Maf transcription factor Mnd1 PF03962.10 KND96654.1 - 0.045 13.4 2.0 0.081 12.5 1.4 1.3 1 0 0 1 1 1 0 Mnd1 family DUF3450 PF11932.3 KND96654.1 - 0.2 10.9 6.0 0.046 12.9 1.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Cpn60_TCP1 PF00118.19 KND96655.1 - 3.1e-136 454.8 7.9 3.6e-136 454.6 5.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PRAI PF00697.17 KND96656.1 - 4.4e-40 137.3 0.0 1e-35 123.1 0.0 2.1 2 0 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase IF2_N PF04760.10 KND96656.1 - 0.12 12.0 0.0 1.8 8.2 0.0 2.6 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region Vps53_N PF04100.7 KND96657.1 - 7.8e-64 215.8 18.9 7.8e-64 215.8 13.1 2.2 2 1 0 2 2 2 1 Vps53-like, N-terminal Kelch_5 PF13854.1 KND96658.1 - 9.7e-33 111.6 15.3 4.5e-09 36.0 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.1 KND96658.1 - 3.4e-29 100.3 7.8 1.7e-07 30.8 0.1 6.4 4 1 2 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 KND96658.1 - 3.4e-27 93.9 5.8 2.6e-06 27.4 0.1 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 KND96658.1 - 2.9e-24 84.1 5.7 5.8e-09 35.7 0.1 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 KND96658.1 - 2e-21 75.2 10.4 1.9e-12 46.5 0.4 6.3 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.10 KND96658.1 - 7e-16 57.2 3.9 2.2e-08 33.5 0.2 6.0 6 0 0 6 6 6 2 Kelch motif RAG2 PF03089.9 KND96658.1 - 0.08 11.6 0.1 1.4 7.5 0.0 2.8 3 0 0 3 3 3 0 Recombination activating protein 2 IncA PF04156.9 KND96658.1 - 0.11 12.0 44.8 0.024 14.2 3.2 4.1 2 1 0 4 4 4 0 IncA protein Baculo_PEP_C PF04513.7 KND96658.1 - 0.12 12.1 16.5 0.47 10.2 0.1 3.7 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.1 KND96658.1 - 0.73 8.9 44.4 0.011 14.9 1.4 4.3 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding FUSC PF04632.7 KND96658.1 - 4.8 5.4 5.9 5.8 5.2 0.8 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family Arrestin_N PF00339.24 KND96660.1 - 1.2e-13 51.1 0.0 6.8e-13 48.6 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KND96660.1 - 3.4e-09 36.9 0.3 3e-06 27.3 0.0 3.5 2 2 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain RRM_1 PF00076.17 KND96663.1 - 1.4e-42 143.1 0.0 6.3e-20 70.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND96663.1 - 6.4e-33 112.5 0.0 9e-16 57.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND96663.1 - 6.9e-19 67.4 0.0 2.5e-09 36.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMGL-like PF00682.14 KND96665.1 - 2.2e-71 240.2 0.0 3.1e-71 239.7 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 KND96665.1 - 1.5e-27 95.9 0.1 2.9e-27 95.0 0.1 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Ribosomal_L13 PF00572.13 KND96666.1 - 3.4e-27 95.0 0.0 5.7e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 Aldedh PF00171.17 KND96668.1 - 5.1e-112 374.5 0.0 6.1e-112 374.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF676 PF05057.9 KND96669.1 - 3.1e-08 33.1 0.0 2.7e-07 30.1 0.0 2.2 1 1 1 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KND96669.1 - 1e-06 28.5 0.0 3.3e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KND96669.1 - 5e-05 23.0 0.0 0.0001 22.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 KND96669.1 - 7.5e-05 21.9 0.0 0.00099 18.2 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.2 KND96669.1 - 0.00018 21.4 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KND96669.1 - 0.00068 19.2 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 KND96669.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 KND96669.1 - 0.0029 16.6 0.0 0.0037 16.2 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 KND96669.1 - 0.11 11.7 0.0 0.24 10.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 2) Thioesterase PF00975.15 KND96669.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain FAD_binding_3 PF01494.14 KND96670.1 - 6.9e-21 74.6 0.1 8.1e-19 67.8 0.1 2.3 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 KND96670.1 - 6.4e-05 21.9 0.0 0.0001 21.2 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.1 KND96670.1 - 9.5e-05 22.2 0.0 0.0023 17.7 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KND96670.1 - 0.00052 19.0 0.5 0.02 13.8 0.1 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.19 KND96670.1 - 0.001 18.0 0.1 0.052 12.4 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KND96670.1 - 0.0034 17.2 0.0 0.0094 15.8 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KND96670.1 - 0.013 14.1 0.0 1.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 KND96670.1 - 0.015 15.3 0.1 2.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KND96670.1 - 0.1 11.6 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Thi4 family NAP PF00956.13 KND96671.1 - 3.3e-30 105.0 1.1 4.5e-30 104.5 0.7 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) RNA_pol_I_A49 PF06870.7 KND96672.1 - 2.5e-116 388.4 0.1 2.8e-116 388.2 0.1 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DMAP1 PF05499.7 KND96672.1 - 0.00026 20.5 0.8 0.00062 19.3 0.2 1.8 2 0 0 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) DnaJ PF00226.26 KND96673.1 - 1.6e-15 56.5 1.1 2.3e-15 56.0 0.8 1.3 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 KND96673.1 - 4.8e-13 48.4 0.0 7.5e-13 47.7 0.0 1.4 1 0 0 1 1 1 1 CSL zinc finger Lar_restr_allev PF14354.1 KND96673.1 - 0.026 14.8 0.4 0.049 13.9 0.3 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar Abhydrolase_6 PF12697.2 KND96675.1 - 5.4e-09 36.2 0.0 2.9e-08 33.8 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family LCAT PF02450.10 KND96675.1 - 2.5e-06 26.7 0.0 5.4e-06 25.6 0.0 1.5 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.15 KND96675.1 - 0.00016 21.3 0.0 0.00054 19.5 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF900 PF05990.7 KND96675.1 - 0.0051 16.1 0.0 0.0084 15.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 KND96675.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 KND96675.1 - 0.058 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_M41 PF01434.13 KND96677.1 - 5.3e-76 254.8 0.0 9.5e-76 253.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KND96677.1 - 1.6e-42 144.8 0.0 3.6e-42 143.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 KND96677.1 - 6.5e-06 26.2 0.0 2.4e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.1 KND96677.1 - 0.00013 22.7 0.0 0.00084 20.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 KND96677.1 - 0.0014 17.3 0.1 0.0055 15.4 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus AAA_22 PF13401.1 KND96677.1 - 0.0057 16.8 0.3 0.28 11.3 0.2 2.8 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KND96677.1 - 0.0077 15.9 0.6 0.023 14.4 0.4 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KND96677.1 - 0.013 15.2 0.5 0.048 13.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KND96677.1 - 0.014 14.4 0.0 0.03 13.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 KND96677.1 - 0.023 14.6 0.5 0.12 12.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 KND96677.1 - 0.025 13.9 0.0 0.064 12.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 KND96677.1 - 0.042 13.8 0.1 0.22 11.4 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 KND96677.1 - 0.12 12.7 2.2 0.23 11.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain Fe-ADH_2 PF13685.1 KND96677.1 - 0.14 11.4 1.7 3 7.0 0.0 2.6 3 0 0 3 3 3 0 Iron-containing alcohol dehydrogenase CRC_subunit PF08624.5 KND96679.1 - 2.6e-54 182.8 0.2 4.4e-54 182.1 0.2 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Bro-N PF02498.12 KND96679.1 - 0.015 15.5 0.0 0.051 13.8 0.0 2.0 1 0 0 1 1 1 0 BRO family, N-terminal domain zf-C2H2 PF00096.21 KND96680.1 - 1.2e-05 25.3 4.5 0.019 15.2 0.1 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND96680.1 - 3.8e-05 23.7 5.1 0.014 15.6 0.3 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.7 KND96680.1 - 0.037 14.1 1.3 0.13 12.4 0.8 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding RPAP1_N PF08621.5 KND96681.1 - 0.092 12.3 2.6 0.7 9.5 0.4 2.6 2 0 0 2 2 2 0 RPAP1-like, N-terminal Abhydrolase_1 PF00561.15 KND96683.1 - 5.3e-21 75.2 0.1 7.3e-21 74.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 KND96683.1 - 1.1e-17 63.1 0.0 2e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 KND96683.1 - 3.3e-10 40.2 0.0 5.6e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND96683.1 - 7.7e-06 25.7 0.0 0.00018 21.2 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KND96683.1 - 0.00081 18.8 0.0 0.1 12.0 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DUF2974 PF11187.3 KND96683.1 - 0.027 13.8 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Sod_Cu PF00080.15 KND96686.1 - 1.7e-20 73.6 0.1 2e-20 73.3 0.1 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) OPT PF03169.10 KND96688.1 - 1.4e-161 539.0 41.3 1.6e-161 538.9 28.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein YtzH PF14165.1 KND96688.1 - 0.049 13.8 0.1 0.096 12.9 0.1 1.4 1 0 0 1 1 1 0 YtzH-like protein Amidase PF01425.16 KND96689.1 - 1.9e-86 290.6 0.0 2.2e-86 290.4 0.0 1.0 1 0 0 1 1 1 1 Amidase Endonuclease_NS PF01223.18 KND96691.1 - 8.2e-58 195.4 0.0 1.1e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease FAM150 PF15129.1 KND96691.1 - 0.012 15.4 0.0 0.029 14.2 0.0 1.7 1 0 0 1 1 1 0 FAM150 family Acyl_transf_1 PF00698.16 KND96692.1 - 2.6e-86 289.8 0.0 7.1e-84 281.8 0.0 3.1 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 KND96692.1 - 4e-40 136.0 0.0 7.4e-40 135.1 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 KND96692.1 - 3.9e-31 106.6 0.1 1.3e-30 104.9 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 KND96692.1 - 1.8e-16 60.1 0.0 7e-16 58.2 0.0 2.0 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 KND96692.1 - 0.00039 19.6 0.0 0.0039 16.3 0.0 2.4 1 1 0 1 1 1 1 Nitronate monooxygenase DUF438 PF04282.8 KND96692.1 - 0.18 11.6 1.5 2.5 7.9 0.2 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF438) His_Phos_2 PF00328.17 KND96693.1 - 6.8e-127 423.5 0.1 1e-126 422.9 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 KND96693.1 - 1.2e-05 24.8 0.0 2.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Cir_N PF10197.4 KND96693.1 - 0.13 12.2 1.9 0.29 11.1 1.3 1.6 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR Pribosyl_synth PF14572.1 KND96695.1 - 1.7e-40 138.7 1.4 5e-39 133.9 1.0 2.1 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KND96695.1 - 1.1e-05 25.1 0.3 7.1e-05 22.5 0.2 2.1 1 1 0 1 1 1 1 Phosphoribosyl transferase domain SRR1 PF07985.7 KND96696.1 - 6e-19 67.7 0.1 1.3e-18 66.6 0.1 1.6 1 0 0 1 1 1 1 SRR1 HSF_DNA-bind PF00447.12 KND96697.1 - 8.4e-36 122.2 4.7 1.6e-35 121.3 3.2 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 KND96697.1 - 2.2e-26 92.0 0.7 7e-26 90.4 0.5 1.8 2 0 0 2 2 2 1 Response regulator receiver domain Spermine_synth PF01564.12 KND96697.1 - 0.01 14.8 0.0 0.019 13.9 0.0 1.4 1 0 0 1 1 1 0 Spermine/spermidine synthase DUF904 PF06005.7 KND96697.1 - 0.065 13.5 0.3 0.15 12.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) GIY-YIG PF01541.19 KND96699.1 - 4.2e-08 33.4 0.0 7.8e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain HeLo PF14479.1 KND96699.1 - 0.059 13.1 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation zf-RING_2 PF13639.1 KND96699.1 - 0.1 12.4 11.2 0.34 10.7 6.7 2.3 2 0 0 2 2 2 0 Ring finger domain zf-rbx1 PF12678.2 KND96699.1 - 0.13 12.4 5.4 0.08 13.0 2.2 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger zf-HC5HC2H PF13771.1 KND96699.1 - 0.13 12.3 4.6 0.34 11.1 3.1 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-Apc11 PF12861.2 KND96699.1 - 0.22 11.3 8.9 0.11 12.2 3.8 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.1 KND96699.1 - 0.43 10.5 6.8 1.6 8.7 3.1 2.4 2 1 0 2 2 2 0 PHD-zinc-finger like domain C1_3 PF07649.7 KND96699.1 - 2.4 8.2 8.2 12 6.0 5.7 2.2 1 1 0 1 1 1 0 C1-like domain zf-RING_4 PF14570.1 KND96699.1 - 2.7 7.6 12.9 0.34 10.5 5.4 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Glyco_hydro_31 PF01055.21 KND96700.1 - 1.4e-135 452.5 3.3 1.9e-135 452.1 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KND96700.1 - 6.9e-20 70.6 0.7 2.9e-19 68.6 0.2 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like BRE1 PF08647.6 KND96702.1 - 5.1e-24 84.0 12.0 5.1e-24 84.0 8.3 7.0 5 2 1 6 6 3 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 KND96702.1 - 1.4e-09 37.7 7.5 2.5e-09 36.9 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KND96702.1 - 4.6e-08 32.5 6.3 8e-08 31.8 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND96702.1 - 2.2e-07 30.4 8.1 4e-07 29.6 5.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KND96702.1 - 3.6e-07 29.7 6.5 7.1e-07 28.7 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KND96702.1 - 1.1e-06 28.2 7.2 2e-06 27.5 5.0 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.1 KND96702.1 - 0.0059 16.1 2.3 0.012 15.1 1.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 KND96702.1 - 0.0082 16.0 5.0 0.02 14.7 3.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KND96702.1 - 0.01 15.6 3.0 0.022 14.5 2.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF3755 PF12579.3 KND96702.1 - 0.012 15.0 1.1 0.037 13.4 0.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3755) zf-rbx1 PF12678.2 KND96702.1 - 0.049 13.7 2.6 0.11 12.6 1.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C2H2 PF00096.21 KND96702.1 - 0.054 13.8 0.2 0.054 13.8 0.1 2.2 2 0 0 2 2 1 0 Zinc finger, C2H2 type zf-RING_UBOX PF13445.1 KND96702.1 - 0.063 13.0 5.1 0.099 12.3 1.9 2.7 2 0 0 2 2 2 0 RING-type zinc-finger zf-met PF12874.2 KND96702.1 - 0.52 10.5 2.3 0.58 10.4 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-RING_4 PF14570.1 KND96702.1 - 1.4 8.5 5.8 3.1 7.4 4.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Bromodomain PF00439.20 KND96703.1 - 2.5e-43 145.8 0.7 2.7e-22 78.4 0.1 3.0 3 0 0 3 3 3 2 Bromodomain DUF1013 PF06242.6 KND96703.1 - 0.048 13.6 4.6 0.15 12.0 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1013) Dus PF01207.12 KND96704.1 - 7.9e-76 254.8 0.0 1e-75 254.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.15 KND96704.1 - 0.00013 21.1 0.1 0.00019 20.5 0.1 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TMP-TENI PF02581.12 KND96704.1 - 0.00059 19.0 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Resolvase PF00239.16 KND96704.1 - 0.004 17.0 0.0 0.0084 15.9 0.0 1.5 1 0 0 1 1 1 1 Resolvase, N terminal domain His_biosynth PF00977.16 KND96704.1 - 0.0043 16.3 0.2 0.033 13.4 0.1 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.16 KND96704.1 - 0.011 14.7 0.0 0.019 13.9 0.0 1.3 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase MTHFR PF02219.12 KND96704.1 - 0.019 14.0 0.1 2.9 6.9 0.0 2.4 1 1 1 2 2 2 0 Methylenetetrahydrofolate reductase SMC_N PF02463.14 KND96705.1 - 2.5e-64 216.5 54.3 2.3e-61 206.8 37.6 3.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KND96705.1 - 6e-23 81.0 0.0 2.5e-22 79.0 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KND96705.1 - 5.3e-10 39.7 27.9 2.9e-05 24.1 0.0 4.9 3 2 1 4 4 4 2 AAA domain AAA_23 PF13476.1 KND96705.1 - 1.1e-09 38.8 15.3 1.1e-09 38.8 10.6 7.8 3 2 1 4 4 4 1 AAA domain AAA_29 PF13555.1 KND96705.1 - 9.2e-05 21.8 0.0 0.00022 20.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain IncA PF04156.9 KND96705.1 - 1.5 8.3 153.6 0.0095 15.5 12.8 8.3 3 2 5 8 8 8 0 IncA protein RNA_polI_A14 PF08203.6 KND96706.1 - 1.8e-19 69.7 2.4 1.9e-19 69.6 0.0 2.3 2 1 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 Utp11 PF03998.8 KND96706.1 - 3.7e-05 23.6 17.0 4.3e-05 23.4 11.8 1.2 1 0 0 1 1 1 1 Utp11 protein GAGA_bind PF06217.7 KND96706.1 - 0.096 12.6 16.8 0.12 12.3 11.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Parvo_coat PF00740.13 KND96706.1 - 0.15 10.9 6.3 0.18 10.7 4.4 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DnaJ PF00226.26 KND96709.1 - 1.1e-23 82.7 3.1 1.8e-23 82.0 2.1 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KND96709.1 - 5.5e-18 64.6 1.0 1.3e-16 60.2 0.0 2.7 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KND96709.1 - 3.2e-14 52.7 17.0 7.2e-14 51.5 11.8 1.6 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KND96709.1 - 0.0071 16.0 4.5 1.5 8.5 0.1 2.6 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 KND96709.1 - 0.58 10.5 7.1 0.18 12.1 2.8 1.8 2 0 0 2 2 2 0 Cytochrome c3 zf-C2H2 PF00096.21 KND96713.1 - 2.2e-08 33.9 7.4 0.00078 19.6 0.7 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KND96713.1 - 1.5e-06 28.1 6.9 0.0015 18.6 0.0 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KND96713.1 - 5.1e-05 23.3 7.0 0.016 15.4 0.9 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KND96713.1 - 0.00017 21.6 1.1 0.0033 17.5 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KND96713.1 - 0.062 13.4 1.7 0.34 11.1 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PHF5 PF03660.9 KND96713.1 - 0.095 12.7 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 PHF5-like protein zf-C2HC_2 PF13913.1 KND96713.1 - 0.52 10.0 4.4 2 8.1 0.2 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.10 KND96713.1 - 0.82 9.4 3.3 0.77 9.5 0.1 2.2 1 1 1 2 2 2 0 BED zinc finger DUF2413 PF10310.4 KND96714.1 - 0.095 11.5 1.0 0.099 11.4 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF4240 PF14024.1 KND96714.1 - 0.12 12.2 0.1 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) PIR PF00399.14 KND96721.1 - 1e-13 50.0 68.8 8.8e-06 24.8 5.3 6.6 6 0 0 6 6 6 6 Yeast PIR protein repeat PP2C_2 PF13672.1 KND96721.1 - 0.011 15.1 4.6 1.1 8.6 0.2 2.6 1 1 1 2 2 2 0 Protein phosphatase 2C Med15 PF09606.5 KND96721.1 - 0.26 9.4 20.0 0.29 9.2 13.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pkinase PF00069.20 KND96722.1 - 6.4e-69 231.9 0.4 1.3e-68 231.0 0.2 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND96722.1 - 2.9e-31 108.4 0.0 1e-21 77.1 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KND96722.1 - 1.4e-07 30.8 0.3 4.2e-05 22.6 0.0 2.9 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.9 KND96722.1 - 0.037 13.0 0.0 0.071 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_14 PF13428.1 KND96725.1 - 5.7e-05 23.3 9.7 1.1 10.0 0.9 6.5 6 1 1 7 7 7 2 Tetratricopeptide repeat Suf PF05843.9 KND96725.1 - 0.0023 17.7 11.9 2.5 7.7 0.1 5.2 3 1 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_12 PF13424.1 KND96725.1 - 0.004 17.0 6.4 0.94 9.4 0.2 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KND96725.1 - 0.0054 16.8 1.9 3.9 7.9 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KND96725.1 - 0.0055 16.3 11.3 0.3 10.7 0.1 5.7 6 0 0 6 6 6 1 TPR repeat NRDE-2 PF08424.5 KND96725.1 - 0.021 13.7 13.1 0.61 8.9 0.4 4.7 2 2 1 3 3 3 0 NRDE-2, necessary for RNA interference TPR_7 PF13176.1 KND96725.1 - 0.043 13.6 5.5 8.9 6.3 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 KND96725.1 - 0.38 10.7 10.7 6.1 7.0 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.1 KND96725.1 - 0.56 9.3 6.5 3.2 6.8 0.1 3.2 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_8 PF13181.1 KND96725.1 - 9.3 6.2 12.3 0.98 9.3 0.2 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat zf-GRF PF06839.7 KND96727.1 - 0.33 10.8 2.6 12 5.9 0.0 2.4 2 1 0 2 2 2 0 GRF zinc finger Cullin PF00888.17 KND96728.1 - 2.3e-84 284.0 11.9 2.3e-84 284.0 8.3 1.7 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 KND96728.1 - 2e-26 91.5 1.0 2e-26 91.5 0.7 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF4252 PF14060.1 KND96729.1 - 0.065 12.7 0.2 0.065 12.7 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) Aconitase PF00330.15 KND96730.1 - 1.9e-190 633.2 0.1 2.4e-190 632.9 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KND96730.1 - 1.8e-44 151.0 0.0 3.5e-44 150.0 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain MRP-S26 PF14943.1 KND96733.1 - 0.0012 18.4 17.4 0.0012 18.4 12.1 2.7 3 0 0 3 3 3 1 Mitochondrial ribosome subunit S26 Pex14_N PF04695.8 KND96733.1 - 0.011 15.8 1.5 0.011 15.8 1.1 5.8 2 2 2 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region OCD_Mu_crystall PF02423.10 KND96734.1 - 1.2e-20 73.5 0.0 1.4e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 KND96734.1 - 3.7e-08 33.5 0.0 6.9e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 KND96734.1 - 0.0035 17.7 0.0 0.011 16.1 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Alk_phosphatase PF00245.15 KND96737.1 - 1.2e-112 376.7 0.0 1.6e-112 376.3 0.0 1.2 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 KND96737.1 - 3.9e-05 23.1 0.0 0.00012 21.5 0.0 1.8 2 0 0 2 2 2 1 Metalloenzyme superfamily DUF1877 PF08974.5 KND96737.1 - 0.0072 15.9 0.4 0.023 14.3 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1877) Phosphodiest PF01663.17 KND96737.1 - 0.019 14.3 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Lipoprotein_6 PF01441.14 KND96737.1 - 0.027 14.3 0.7 1.9 8.2 0.0 2.5 2 0 0 2 2 2 0 Lipoprotein MFS_1 PF07690.11 KND96738.1 - 6.5e-34 117.1 25.4 6.5e-34 117.1 17.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily NfeD PF01957.13 KND96738.1 - 0.066 13.3 0.2 0.066 13.3 0.1 3.2 4 0 0 4 4 4 0 NfeD-like C-terminal, partner-binding Beta_elim_lyase PF01212.16 KND96739.1 - 5.8e-76 255.3 0.0 8.2e-76 254.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KND96739.1 - 2.1e-06 26.9 0.0 3.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KND96739.1 - 0.042 12.8 0.0 0.15 11.0 0.0 1.9 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Filament PF00038.16 KND96740.1 - 0.0083 15.6 15.7 0.35 10.2 7.4 2.2 1 1 1 2 2 2 2 Intermediate filament protein Macoilin PF09726.4 KND96740.1 - 4 5.5 13.9 7.7 4.6 9.6 1.3 1 0 0 1 1 1 0 Transmembrane protein APG6 PF04111.7 KND96740.1 - 6.3 5.7 18.3 2.6 7.0 0.5 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 FlxA PF14282.1 KND96740.1 - 6.5 6.7 13.8 1.2 9.1 5.2 2.6 1 1 1 2 2 2 0 FlxA-like protein MFS_1 PF07690.11 KND96741.1 - 1.1e-13 50.6 6.3 1.1e-13 50.6 4.4 2.8 3 1 0 3 3 3 2 Major Facilitator Superfamily RabGAP-TBC PF00566.13 KND96742.1 - 0.019 14.4 6.3 0.26 10.7 0.0 3.3 2 1 1 3 3 3 0 Rab-GTPase-TBC domain ubiquitin PF00240.18 KND96748.1 - 3.1e-169 548.6 31.3 1.6e-33 113.9 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.3 KND96748.1 - 3.6e-97 318.1 28.4 6.2e-19 67.4 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KND96748.1 - 1.7e-29 101.9 15.8 0.00021 21.4 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KND96748.1 - 7.5e-27 94.0 3.2 0.001 18.7 0.0 5.0 5 0 0 5 5 5 5 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KND96748.1 - 6.2e-17 61.4 4.9 0.17 11.7 0.0 5.9 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KND96748.1 - 1.1e-16 60.7 4.7 0.18 12.0 0.0 5.2 1 1 4 5 5 5 5 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 KND96748.1 - 2.4e-13 49.9 0.0 2 8.4 0.0 5.9 5 0 0 5 5 5 5 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.9 KND96748.1 - 7.7e-08 31.7 1.4 2.8 7.0 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase TUG-UBL1 PF11470.3 KND96748.1 - 1.9e-07 30.8 9.3 6.3 6.7 0.0 5.2 5 0 0 5 5 5 5 GLUT4 regulating protein TUG FlgD_ig PF13860.1 KND96748.1 - 1.6e-05 24.5 8.5 19 5.1 0.0 5.3 5 0 0 5 5 5 0 FlgD Ig-like domain Big_3_3 PF13750.1 KND96748.1 - 0.00013 21.3 0.0 65 2.9 0.0 4.9 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 KND96748.1 - 0.00032 19.1 18.9 3.1 5.9 0.2 6.7 6 4 0 6 6 6 4 Plexin cytoplasmic RasGAP domain ACT_4 PF13291.1 KND96748.1 - 0.00038 20.7 1.5 1.4e+02 2.9 0.0 5.1 5 0 0 5 5 5 0 ACT domain CTDII PF01556.13 KND96748.1 - 0.02 14.7 19.9 11 6.0 0.2 5.4 1 1 4 5 5 5 0 DnaJ C terminal domain Tash_PEST PF07708.6 KND96748.1 - 0.025 14.4 38.3 4.5 7.3 1.2 5.4 5 0 0 5 5 5 0 Tash protein PEST motif GABP-alpha PF11620.3 KND96748.1 - 0.058 13.3 11.8 63 3.6 0.1 5.0 5 0 0 5 5 5 0 GA-binding protein alpha chain FERM_N PF09379.5 KND96748.1 - 0.13 12.3 17.1 58 3.8 0.1 7.0 5 5 0 5 5 5 0 FERM N-terminal domain DUF3781 PF12636.2 KND96748.1 - 0.78 9.7 11.2 1.3e+02 2.5 0.1 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3781) Ecm29 PF13001.2 KND96749.1 - 1.2e-124 416.5 1.7 3e-124 415.2 1.2 1.7 1 0 0 1 1 1 1 Proteasome stabiliser HEAT PF02985.17 KND96749.1 - 1.5e-13 49.5 5.2 0.0023 17.8 0.0 8.7 9 0 0 9 9 9 2 HEAT repeat Vac14_Fab1_bd PF12755.2 KND96749.1 - 2.5e-10 40.6 0.3 0.00031 21.0 0.0 6.1 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KND96749.1 - 0.0017 18.8 13.0 13 6.3 0.0 8.8 10 2 1 11 11 11 1 HEAT-like repeat Ipi1_N PF12333.3 KND96749.1 - 0.0033 17.3 0.4 0.2 11.6 0.0 4.4 4 0 0 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation DUF1546 PF07571.8 KND96749.1 - 0.024 14.7 0.3 16 5.6 0.0 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF1546) TetR_C_8 PF14278.1 KND96749.1 - 0.12 12.8 2.3 0.47 10.8 0.1 3.3 3 0 0 3 3 3 0 Transcriptional regulator C-terminal region DUF2206 PF09971.4 KND96750.1 - 0.023 13.5 0.3 0.026 13.3 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF1370 PF07114.6 KND96750.1 - 0.03 13.5 0.1 0.033 13.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1370) DUF1673 PF07895.6 KND96750.1 - 0.085 12.3 0.2 0.087 12.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) P12 PF12669.2 KND96750.1 - 0.21 11.8 1.0 0.3 11.3 0.7 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family IF-2B PF01008.12 KND96751.1 - 6e-76 255.1 5.8 3.3e-39 134.5 0.0 2.4 3 0 0 3 3 3 2 Initiation factor 2 subunit family SOBP PF15279.1 KND96751.1 - 7.3 6.8 10.9 4.1 7.6 4.9 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein HAD PF12710.2 KND96752.1 - 1.3e-19 71.1 0.0 4.5e-19 69.3 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KND96752.1 - 2.6e-15 56.0 0.1 4.6e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KND96752.1 - 2.3e-13 51.0 1.2 3.4e-10 40.7 0.4 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KND96752.1 - 1.8e-12 47.0 0.0 4.9e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KND96752.1 - 0.00052 19.6 0.6 0.011 15.3 0.0 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KND96752.1 - 0.019 15.1 0.1 0.084 13.0 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase ACR_tran PF00873.14 KND96752.1 - 0.065 10.6 0.0 0.1 10.0 0.0 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family SMK-1 PF04802.10 KND96753.1 - 0.0043 16.6 0.3 0.0051 16.3 0.2 1.1 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 ATP-synt_F6 PF05511.6 KND96755.1 - 0.048 13.5 0.1 0.048 13.5 0.1 2.5 2 1 1 3 3 3 0 Mitochondrial ATP synthase coupling factor 6 Aldedh PF00171.17 KND96756.1 - 3.9e-19 68.3 1.1 1e-14 53.7 0.4 2.3 2 1 0 2 2 2 2 Aldehyde dehydrogenase family NAD_binding_7 PF13241.1 KND96757.1 - 7.3e-30 103.2 0.0 1.3e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KND96757.1 - 1.1e-15 56.6 0.5 2.1e-15 55.7 0.1 1.7 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KND96757.1 - 6.6e-13 47.3 0.2 1.1e-12 46.6 0.2 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central DUF2152 PF10222.4 KND96757.1 - 0.0051 15.0 0.3 0.0086 14.3 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2152) Phage_int_SAM_4 PF13495.1 KND96757.1 - 0.062 13.6 0.1 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Shikimate_DH PF01488.15 KND96757.1 - 0.076 13.1 0.1 0.21 11.7 0.1 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF2633 PF11119.3 KND96758.1 - 0.0054 16.4 0.0 0.0062 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2633) GDI PF00996.13 KND96759.1 - 6.2e-49 166.5 0.7 8.4e-49 166.0 0.1 1.4 2 0 0 2 2 2 1 GDP dissociation inhibitor Ribosomal_L7Ae PF01248.21 KND96760.1 - 1.5e-25 88.5 1.2 2e-25 88.0 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family NTP_transf_3 PF12804.2 KND96760.1 - 0.01 15.8 0.1 0.015 15.4 0.1 1.4 1 1 0 1 1 1 0 MobA-like NTP transferase domain DUF2096 PF09869.4 KND96760.1 - 0.055 13.3 0.1 0.076 12.8 0.1 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) DUF3512 PF12024.3 KND96760.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) Fez1 PF06818.10 KND96762.1 - 0.0087 16.0 2.9 0.014 15.4 2.0 1.3 1 0 0 1 1 1 1 Fez1 IncA PF04156.9 KND96762.1 - 0.016 14.7 2.2 0.021 14.4 1.5 1.3 1 0 0 1 1 1 0 IncA protein Occludin_ELL PF07303.8 KND96762.1 - 0.018 15.7 2.0 0.054 14.2 1.4 1.8 1 0 0 1 1 1 0 Occludin homology domain Nup54 PF13874.1 KND96762.1 - 0.026 14.1 1.4 0.064 12.9 1.0 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 BLOC1_2 PF10046.4 KND96762.1 - 0.046 13.8 2.1 0.23 11.6 0.2 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 KND96762.1 - 0.069 12.3 0.8 0.085 12.0 0.5 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein APG6 PF04111.7 KND96762.1 - 0.088 11.8 3.1 0.13 11.2 2.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 KND96762.1 - 0.13 10.0 2.6 0.16 9.8 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4140 PF13600.1 KND96762.1 - 0.17 12.3 2.1 0.19 12.1 0.4 2.0 2 0 0 2 2 1 0 N-terminal domain of unknown function (DUF4140) AT_hook PF02178.14 KND96762.1 - 0.25 11.1 6.0 0.62 9.9 4.2 1.7 1 0 0 1 1 1 0 AT hook motif DUF972 PF06156.8 KND96762.1 - 6.3 7.1 8.4 0.62 10.4 2.0 2.2 2 1 0 3 3 2 0 Protein of unknown function (DUF972) Cornichon PF03311.9 KND96763.1 - 2e-45 154.0 5.0 2.2e-45 153.8 3.5 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1634 PF07843.6 KND96763.1 - 0.058 13.0 0.1 0.076 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) DUF1673 PF07895.6 KND96763.1 - 0.066 12.7 2.2 0.073 12.5 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) LRR_4 PF12799.2 KND96765.1 - 1.1e-27 95.1 62.3 5e-07 29.1 6.6 8.8 8 1 1 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KND96765.1 - 7.9e-20 70.3 58.0 1.2e-06 28.1 6.1 7.3 5 1 2 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 KND96765.1 - 0.00037 20.1 60.1 1.3 9.3 0.1 13.9 13 2 1 14 14 14 5 Leucine Rich Repeat LRR_9 PF14580.1 KND96765.1 - 0.00095 18.7 9.8 0.18 11.3 2.3 3.7 2 1 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.1 KND96765.1 - 0.19 11.9 50.4 1 9.6 0.2 11.3 9 3 0 9 9 9 0 Leucine Rich repeat LRR_7 PF13504.1 KND96765.1 - 4.5 7.9 53.3 4.5 7.9 0.1 12.7 14 0 0 14 14 14 0 Leucine rich repeat RRM_1 PF00076.17 KND96766.1 - 1.4e-39 133.5 0.0 1.2e-14 53.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND96766.1 - 9.5e-29 99.1 0.0 9.1e-11 41.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND96766.1 - 1.8e-21 75.6 0.0 1.4e-09 37.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KND96766.1 - 0.00056 19.6 0.0 0.0023 17.6 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KND96766.1 - 0.04 13.7 0.0 0.17 11.7 0.0 2.0 3 0 0 3 3 3 0 RNA binding motif Nop14 PF04147.7 KND96767.1 - 0.09 10.6 14.2 0.13 10.2 9.8 1.1 1 0 0 1 1 1 0 Nop14-like family Histone PF00125.19 KND96768.1 - 8.6e-33 112.2 0.4 1.4e-32 111.6 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KND96768.1 - 1.8e-06 28.0 0.0 2.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KND96768.1 - 0.0008 19.4 0.1 0.0017 18.3 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KND96768.1 - 0.039 13.6 0.1 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KND96768.1 - 0.052 12.7 1.2 0.14 11.4 0.1 1.8 1 1 1 2 2 2 0 Centromere kinetochore component CENP-T Oxidored_q6 PF01058.17 KND96771.1 - 1.9e-22 79.2 0.1 2.9e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit EnY2 PF10163.4 KND96772.1 - 1.2e-29 102.0 0.2 1.4e-29 101.8 0.1 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 NUDIX PF00293.23 KND96773.1 - 8.4e-16 57.8 0.3 1.4e-15 57.1 0.0 1.4 2 0 0 2 2 2 1 NUDIX domain zf-C4_Topoisom PF01396.14 KND96774.1 - 0.069 12.6 0.1 0.16 11.5 0.1 1.6 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger TPR_1 PF00515.23 KND96777.1 - 1.3e-53 176.5 24.6 1.7e-07 30.5 0.0 11.1 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 KND96777.1 - 5e-52 169.6 18.8 1.2e-06 27.9 0.0 10.8 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 KND96777.1 - 7.5e-50 166.4 17.7 7.8e-11 41.4 0.1 6.6 3 2 2 6 6 6 6 TPR repeat TPR_8 PF13181.1 KND96777.1 - 1.1e-32 109.3 13.1 3.1e-05 23.4 0.0 10.2 9 1 2 11 11 11 8 Tetratricopeptide repeat TPR_17 PF13431.1 KND96777.1 - 1.6e-32 108.9 15.3 0.00099 19.1 0.0 10.4 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_12 PF13424.1 KND96777.1 - 1.1e-30 105.3 18.3 4.8e-07 29.6 0.1 7.4 4 2 3 7 7 7 7 Tetratricopeptide repeat TPR_16 PF13432.1 KND96777.1 - 2.5e-26 91.7 32.7 1.3e-06 28.8 0.0 7.7 5 2 3 8 8 7 7 Tetratricopeptide repeat TPR_14 PF13428.1 KND96777.1 - 2.9e-26 89.5 26.4 2e-05 24.7 0.1 10.3 5 2 5 10 10 9 7 Tetratricopeptide repeat TPR_7 PF13176.1 KND96777.1 - 6.6e-21 72.3 8.7 0.053 13.3 0.0 9.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 KND96777.1 - 4.9e-20 71.6 25.1 0.00035 20.8 0.2 7.6 5 3 1 7 7 6 6 Tetratricopeptide repeat TPR_6 PF13174.1 KND96777.1 - 4.4e-17 61.2 19.7 0.002 18.4 0.0 10.2 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_9 PF13371.1 KND96777.1 - 6.5e-15 54.7 18.3 8.8e-05 22.2 0.0 6.6 4 2 4 8 8 7 7 Tetratricopeptide repeat Apc3 PF12895.2 KND96777.1 - 1.8e-10 40.7 17.1 1.1e-05 25.4 0.2 4.3 4 0 0 4 4 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KND96777.1 - 2.4e-08 33.3 18.8 0.0025 16.9 0.3 4.9 3 3 2 5 5 5 3 Tetratricopeptide repeat NARP1 PF12569.3 KND96777.1 - 0.065 11.9 0.0 0.065 11.9 0.0 6.8 4 3 3 8 8 6 0 NMDA receptor-regulated protein 1 PPTA PF01239.17 KND96777.1 - 0.45 9.9 1.7 2.7 7.4 0.1 2.9 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat NAD_kinase PF01513.16 KND96778.1 - 1e-47 162.3 0.0 1.3e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 KND96778.1 - 0.014 14.8 0.0 0.035 13.5 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Hist_deacetyl PF00850.14 KND96779.1 - 1e-79 268.0 0.0 1.4e-79 267.6 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DUF4604 PF15377.1 KND96779.1 - 0.5 10.5 12.1 0.74 10.0 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) zf-DHHC PF01529.15 KND96781.1 - 2.4e-19 69.3 12.0 3.3e-19 68.9 8.3 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase PgaD PF13994.1 KND96781.1 - 0.59 9.6 3.3 0.25 10.8 0.7 1.6 2 0 0 2 2 2 0 PgaD-like protein ABC2_membrane_3 PF12698.2 KND96781.1 - 5.2 6.0 10.1 7.5 5.4 7.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein UAA PF08449.6 KND96782.1 - 2.8e-68 230.0 17.8 3.4e-68 229.7 12.3 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KND96782.1 - 3.6e-07 30.2 26.3 6.3e-05 23.0 7.4 3.4 3 0 0 3 3 3 3 EamA-like transporter family TPT PF03151.11 KND96782.1 - 9.3e-05 22.1 20.1 0.00039 20.0 6.3 2.5 2 1 1 3 3 3 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 KND96782.1 - 0.00076 18.6 10.4 0.0013 17.9 7.2 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 KND96782.1 - 0.0028 17.8 21.6 0.027 14.6 1.0 3.2 2 1 0 3 3 3 2 Multidrug resistance efflux transporter UPF0546 PF10639.4 KND96782.1 - 0.23 11.3 4.0 1.5 8.6 0.4 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 DnaJ PF00226.26 KND96784.1 - 1.6e-20 72.6 1.0 3.3e-20 71.5 0.7 1.6 1 0 0 1 1 1 1 DnaJ domain HTH_Tnp_IS630 PF01710.11 KND96784.1 - 0.015 14.9 1.5 0.025 14.2 1.0 1.4 1 1 0 1 1 1 0 Transposase RPT PF13446.1 KND96784.1 - 0.04 13.3 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein RRM_1 PF00076.17 KND96784.1 - 0.049 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADIP PF11559.3 KND96784.1 - 0.068 13.0 6.2 0.12 12.3 4.3 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding eIF-4B PF06273.6 KND96784.1 - 0.65 8.6 4.5 0.83 8.3 3.1 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Cyt-b5 PF00173.23 KND96785.1 - 3e-26 91.0 0.3 3.7e-26 90.7 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HD PF01966.17 KND96786.1 - 5.8e-10 39.2 0.0 8.4e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 HD domain RRM_1 PF00076.17 KND96787.1 - 3.2e-16 58.7 0.1 6.3e-16 57.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND96787.1 - 9.4e-13 47.9 0.1 2e-12 46.9 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND96787.1 - 3.4e-11 42.8 0.3 7.7e-11 41.6 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KND96787.1 - 0.0038 16.9 0.3 0.012 15.4 0.1 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Maf PF02545.9 KND96788.1 - 1.5e-39 135.1 0.0 1.8e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Ribosomal_S30 PF04758.9 KND96789.1 - 0.059 13.1 0.0 0.059 13.1 0.0 1.0 1 0 0 1 1 1 0 Ribosomal protein S30 His_Phos_1 PF00300.17 KND96790.1 - 5.5e-22 78.5 0.0 1.4e-21 77.2 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) 2-oxoacid_dh PF00198.18 KND96792.1 - 2.9e-74 249.2 0.4 3.7e-74 248.8 0.3 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KND96792.1 - 2.2e-17 62.4 0.1 4.5e-17 61.4 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KND96792.1 - 2.8e-15 55.6 0.1 5.7e-15 54.6 0.1 1.6 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.3 KND96792.1 - 0.046 13.9 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) PA_decarbox PF05870.6 KND96792.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) Ribosomal_60s PF00428.14 KND96792.1 - 1 9.8 20.4 0.26 11.7 9.6 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein RNase_HII PF01351.13 KND96793.1 - 3.1e-55 186.8 0.0 4e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Mito_carr PF00153.22 KND96794.1 - 1.5e-64 213.7 1.2 2.1e-22 78.6 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Syja_N PF02383.13 KND96796.1 - 1.7e-83 280.0 0.2 1.7e-83 280.0 0.1 1.7 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.18 KND96796.1 - 2.3e-22 80.1 0.0 3.8e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YEATS PF03366.11 KND96797.1 - 2.5e-32 110.4 0.9 4.8e-32 109.5 0.6 1.5 1 0 0 1 1 1 1 YEATS family DivIC PF04977.10 KND96797.1 - 7.6 6.1 7.5 5 6.6 2.3 2.2 1 1 1 2 2 2 0 Septum formation initiator Sec23_trunk PF04811.10 KND96799.1 - 5.7e-49 166.6 0.0 8.1e-48 162.8 0.0 2.1 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KND96799.1 - 6.4e-29 99.4 0.3 1.3e-28 98.4 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KND96799.1 - 2.2e-28 98.5 0.0 4.9e-28 97.4 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 KND96799.1 - 6.1e-11 41.8 0.0 1.4e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.10 KND96799.1 - 1.9e-08 33.7 1.9 4e-08 32.6 1.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Corona_S1 PF01600.11 KND96799.1 - 0.02 13.2 0.1 0.055 11.7 0.1 1.6 2 0 0 2 2 2 0 Coronavirus S1 glycoprotein tRNA-synt_2 PF00152.15 KND96800.1 - 7.4e-71 238.6 0.0 9.9e-71 238.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KND96800.1 - 1.2e-07 31.4 0.1 2.1e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KND96800.1 - 0.00018 20.8 0.1 0.033 13.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) RhoGAP PF00620.22 KND96801.1 - 8.1e-37 126.1 0.0 2.1e-36 124.8 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.14 KND96801.1 - 3.7e-32 111.5 2.9 5.6e-29 101.1 0.1 3.5 3 0 0 3 3 3 2 RasGEF domain RasGEF_N PF00618.15 KND96801.1 - 2.3e-13 50.1 1.5 1e-12 48.0 0.7 2.6 1 1 0 1 1 1 1 RasGEF N-terminal motif 60KD_IMP PF02096.15 KND96802.1 - 3.7e-38 131.1 2.0 3.7e-38 131.1 1.4 1.4 2 0 0 2 2 2 1 60Kd inner membrane protein YppG PF14179.1 KND96802.1 - 0.57 10.8 4.6 0.86 10.2 2.1 2.0 2 0 0 2 2 2 0 YppG-like protein SMC_N PF02463.14 KND96804.1 - 1.9e-15 56.6 45.6 1.3e-14 53.9 31.6 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KND96804.1 - 5.6e-08 33.3 46.9 5.6e-08 33.3 32.5 6.4 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 KND96804.1 - 6.8e-05 22.9 28.8 0.0017 18.4 7.9 3.7 3 1 0 4 4 4 2 AAA domain DUF3584 PF12128.3 KND96804.1 - 0.00014 19.4 27.6 0.00014 19.4 19.1 3.8 2 2 2 4 4 4 1 Protein of unknown function (DUF3584) AAA_15 PF13175.1 KND96804.1 - 0.0011 18.1 30.0 0.0011 18.1 20.8 4.3 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KND96804.1 - 0.0014 18.0 0.0 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 KND96804.1 - 0.0019 16.7 84.5 0.086 11.2 0.1 5.4 3 2 1 4 4 4 3 AAA domain Reo_sigmaC PF04582.7 KND96804.1 - 0.56 9.3 23.2 0.91 8.6 1.7 4.3 2 2 3 5 5 5 0 Reovirus sigma C capsid protein SSF PF00474.12 KND96806.1 - 1.1e-06 27.5 26.2 1.7e-06 26.9 17.1 2.0 1 1 0 1 1 1 1 Sodium:solute symporter family DUF336 PF03928.9 KND96808.1 - 1.1e-20 73.7 0.0 1.3e-20 73.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF336) DUF3980 PF13140.1 KND96810.1 - 0.11 12.8 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3980) CMD PF02627.15 KND96811.1 - 1.1e-05 25.1 0.0 0.0016 18.1 0.0 2.4 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family CENP-U PF13097.1 KND96811.1 - 0.039 13.8 0.0 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit AFG1_ATPase PF03969.11 KND96812.1 - 2.4e-57 194.4 1.7 1.3e-54 185.4 0.3 3.2 2 1 0 2 2 2 2 AFG1-like ATPase AAA_22 PF13401.1 KND96812.1 - 0.012 15.7 0.0 0.054 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KND96812.1 - 0.016 15.5 0.3 3.1 8.1 0.0 3.3 3 0 0 3 3 3 0 ABC transporter NACHT PF05729.7 KND96812.1 - 0.016 14.8 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 KND96812.1 - 0.04 13.9 0.0 1.1 9.2 0.0 3.1 2 2 1 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.17 KND96812.1 - 0.043 13.9 0.1 0.87 9.7 0.0 3.0 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 KND96812.1 - 0.076 13.2 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Myotub-related PF06602.9 KND96813.1 - 3.4e-120 401.0 0.2 4.4e-120 400.6 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 KND96813.1 - 0.00071 19.8 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KND96813.1 - 0.0026 17.1 0.0 0.0052 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KND96813.1 - 0.03 13.8 0.0 0.079 12.5 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Oxysterol_BP PF01237.13 KND96815.1 - 1.9e-132 441.1 0.0 3.1e-132 440.3 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_2 PF12796.2 KND96815.1 - 6.7e-18 64.8 0.1 1.8e-10 41.0 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KND96815.1 - 5.7e-16 58.1 0.1 3.1e-08 33.5 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KND96815.1 - 1e-14 54.5 0.0 4.7e-09 36.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KND96815.1 - 3.2e-13 48.7 0.0 7.3e-06 25.5 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 KND96815.1 - 1.8e-11 43.1 0.0 4.1e-05 23.4 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat PH PF00169.24 KND96815.1 - 5.7e-09 36.1 0.1 1.3e-08 34.9 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 KND96815.1 - 3.3e-08 33.4 0.2 8.2e-08 32.2 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 KND96815.1 - 0.0012 19.0 0.4 0.0051 17.0 0.3 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain EMP24_GP25L PF01105.19 KND96817.1 - 4.6e-23 81.8 2.3 4.6e-23 81.8 1.6 1.6 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD Med9 PF07544.8 KND96817.1 - 0.06 13.0 0.2 0.12 12.0 0.2 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF4618 PF15397.1 KND96817.1 - 0.09 12.1 1.3 0.13 11.5 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Prefoldin PF02996.12 KND96817.1 - 0.11 12.1 0.9 0.2 11.3 0.6 1.3 1 0 0 1 1 1 0 Prefoldin subunit DUF1664 PF07889.7 KND96817.1 - 0.12 12.2 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ECR1_N PF14382.1 KND96818.1 - 1e-09 37.5 0.1 3.2e-08 32.7 0.0 2.6 3 0 0 3 3 3 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 KND96818.1 - 0.0023 17.8 0.0 0.024 14.5 0.0 2.3 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 Met_10 PF02475.11 KND96819.1 - 2e-66 223.4 0.0 1e-65 221.1 0.0 2.0 1 1 0 1 1 1 1 Met-10+ like-protein RNase_H2_suC PF08615.6 KND96821.1 - 5.5e-16 58.6 0.0 8.2e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) OTCace PF00185.19 KND96822.1 - 8.8e-43 145.9 0.2 1.6e-42 145.0 0.2 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 KND96822.1 - 1.9e-39 134.5 0.1 3.3e-39 133.7 0.1 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Glyco_hydro_4 PF02056.11 KND96822.1 - 0.00022 20.6 0.0 0.0005 19.4 0.0 1.5 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase DNA_pol_B_3 PF08408.5 KND96822.1 - 0.0083 16.0 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B viral insert IRF PF00605.12 KND96824.1 - 0.3 10.8 1.6 2 8.2 0.3 2.0 1 1 1 2 2 2 0 Interferon regulatory factor transcription factor Sugar_tr PF00083.19 KND96826.1 - 9.7e-156 518.8 31.0 1.1e-155 518.6 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND96826.1 - 9.5e-29 100.1 29.5 3.1e-25 88.6 11.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LMF1 PF06762.9 KND96826.1 - 0.0024 16.7 1.1 0.0048 15.7 0.7 1.5 1 0 0 1 1 1 1 Lipase maturation factor RRM_1 PF00076.17 KND96827.1 - 4.1e-17 61.5 0.1 6.3e-08 32.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND96827.1 - 1.6e-13 50.2 0.0 8.7e-10 38.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND96827.1 - 3.3e-12 46.2 0.2 9.4e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KND96827.1 - 0.02 14.6 0.2 0.13 11.9 0.0 2.3 2 1 0 2 2 2 0 Limkain b1 DUF1789 PF08748.6 KND96827.1 - 0.05 13.7 0.9 0.086 12.9 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1789) bZIP_1 PF00170.16 KND96828.1 - 2e-12 46.8 8.5 3.9e-12 45.9 5.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KND96828.1 - 8.2e-08 31.9 13.1 1.5e-07 31.0 9.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper HALZ PF02183.13 KND96828.1 - 0.036 13.7 2.3 0.09 12.5 1.6 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Uds1 PF15456.1 KND96828.1 - 0.04 13.9 3.0 0.066 13.2 2.1 1.3 1 0 0 1 1 1 0 Up-regulated During Septation bZIP_Maf PF03131.12 KND96828.1 - 0.94 9.8 9.8 0.09 13.0 3.5 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor TUG-UBL1 PF11470.3 KND96830.1 - 1.9e-14 53.3 1.9 1.9e-14 53.3 1.3 2.2 2 0 0 2 2 2 1 GLUT4 regulating protein TUG MIF4G_like_2 PF09090.6 KND96830.1 - 0.0051 16.0 4.3 0.012 14.8 2.2 2.0 2 0 0 2 2 2 1 MIF4G like Abhydrolase_6 PF12697.2 KND96833.1 - 4.9e-22 78.9 0.0 9e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND96833.1 - 6.5e-08 32.4 0.0 2.7e-07 30.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KND96833.1 - 6.8e-07 29.1 0.0 1.1e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 KND96833.1 - 0.01 14.9 0.0 0.023 13.7 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.3 KND96833.1 - 0.13 12.1 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase MutS_V PF00488.16 KND96834.1 - 3.5e-84 281.8 0.0 6.1e-84 281.0 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.15 KND96834.1 - 4.7e-29 100.7 0.0 1.5e-28 99.0 0.0 2.0 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.13 KND96834.1 - 5.3e-27 94.9 1.0 1e-26 94.0 0.7 1.5 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 KND96834.1 - 2e-11 43.9 0.1 6e-11 42.3 0.0 1.9 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 KND96834.1 - 2.5e-11 43.8 0.3 8.2e-11 42.1 0.2 1.9 1 0 0 1 1 1 1 MutS domain II AAA_14 PF13173.1 KND96834.1 - 0.044 13.6 0.3 0.25 11.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.2 KND96836.1 - 3.1e-14 53.0 0.0 6.3e-09 36.0 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KND96836.1 - 2.4e-11 43.7 5.3 6e-06 26.6 0.0 4.9 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND96836.1 - 1.3e-07 31.5 5.3 7.5e-06 26.0 0.0 5.3 6 1 1 7 7 7 1 Ankyrin repeats (many copies) Ank PF00023.25 KND96836.1 - 3.3e-07 29.7 3.3 0.0022 17.7 0.0 5.2 7 0 0 7 7 7 2 Ankyrin repeat Ank_3 PF13606.1 KND96836.1 - 0.00059 19.8 5.4 0.84 10.0 0.0 6.0 7 0 0 7 7 7 1 Ankyrin repeat DUF3077 PF11275.3 KND96836.1 - 0.049 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3077) DUF2433 PF10360.4 KND96838.1 - 2.2e-32 112.1 0.2 1.1e-31 109.8 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.2 KND96838.1 - 1.6e-05 24.7 0.0 3.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KND96838.1 - 0.0078 15.6 0.4 0.03 13.6 0.1 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase NADH_B2 PF14813.1 KND96839.1 - 4.3e-05 23.0 0.5 4.3e-05 23.0 0.3 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 RhodobacterPufX PF11511.3 KND96842.1 - 0.63 9.4 3.1 1.3 8.4 2.1 1.5 1 1 0 1 1 1 0 Intrinsic membrane protein PufX ABC_tran PF00005.22 KND96844.1 - 2e-48 164.1 0.0 2.7e-24 86.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 KND96844.1 - 5.3e-32 110.7 33.5 2.3e-17 62.8 8.4 2.4 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.1 KND96844.1 - 2e-15 57.5 10.9 3e-06 27.4 0.0 4.5 3 1 0 3 3 3 3 AAA domain AAA_22 PF13401.1 KND96844.1 - 2.1e-10 40.8 0.5 2.7e-05 24.3 0.1 3.3 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 KND96844.1 - 3e-10 39.5 0.2 7.6e-05 21.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KND96844.1 - 2.5e-09 37.9 0.0 0.0026 18.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain FtsK_SpoIIIE PF01580.13 KND96844.1 - 2.8e-07 30.2 0.0 0.0043 16.5 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_28 PF13521.1 KND96844.1 - 2.8e-07 30.6 0.1 0.015 15.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 KND96844.1 - 4.8e-07 29.2 6.0 0.0025 17.0 0.1 3.9 3 2 0 3 3 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KND96844.1 - 7.8e-07 29.6 5.4 0.0057 17.0 0.1 3.2 2 1 1 3 3 3 2 AAA domain SbcCD_C PF13558.1 KND96844.1 - 1.7e-06 27.8 0.1 0.065 13.1 0.0 3.2 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 KND96844.1 - 1.8e-06 28.3 1.6 0.056 13.7 0.0 3.4 4 0 0 4 4 2 2 AAA domain AAA_29 PF13555.1 KND96844.1 - 2.1e-06 27.1 0.1 0.028 13.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.17 KND96844.1 - 3.3e-06 27.2 0.0 0.047 13.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_16 PF13191.1 KND96844.1 - 3.4e-06 27.1 0.2 0.0047 16.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 KND96844.1 - 1.2e-05 24.9 0.5 0.33 10.3 0.0 3.5 4 0 0 4 4 4 2 AAA-like domain AAA PF00004.24 KND96844.1 - 1.3e-05 25.4 0.1 0.13 12.4 0.0 3.8 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KND96844.1 - 1.8e-05 24.5 0.0 0.16 11.6 0.0 2.6 2 1 0 2 2 2 2 Archaeal ATPase UPF0079 PF02367.12 KND96844.1 - 3e-05 23.6 0.1 0.033 13.8 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KND96844.1 - 3.4e-05 23.5 0.0 0.2 11.3 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_19 PF13245.1 KND96844.1 - 4e-05 23.2 0.0 0.012 15.3 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain T2SE PF00437.15 KND96844.1 - 5.8e-05 22.1 0.1 0.2 10.5 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_14 PF13173.1 KND96844.1 - 0.00013 21.8 0.0 0.15 11.9 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 KND96844.1 - 0.00036 19.9 0.0 0.66 9.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain cobW PF02492.14 KND96844.1 - 0.00051 19.5 0.7 0.38 10.1 0.1 2.8 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.12 KND96844.1 - 0.00069 19.0 0.1 4.3 6.7 0.0 3.6 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_30 PF13604.1 KND96844.1 - 0.00095 18.7 0.5 0.64 9.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 KND96844.1 - 0.0012 18.7 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 KND96844.1 - 0.0013 17.4 0.0 0.22 10.1 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Pox_A32 PF04665.7 KND96844.1 - 0.0017 17.6 0.1 0.34 10.1 0.0 2.6 2 0 0 2 2 2 1 Poxvirus A32 protein SRP54 PF00448.17 KND96844.1 - 0.002 17.5 0.1 0.63 9.4 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.1 KND96844.1 - 0.0022 17.5 0.2 1.9 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 KND96844.1 - 0.003 16.6 8.5 0.98 8.3 0.0 4.1 4 1 0 4 4 4 1 AAA ATPase domain PRK PF00485.13 KND96844.1 - 0.0053 16.3 0.2 0.31 10.5 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family NTPase_1 PF03266.10 KND96844.1 - 0.006 16.3 0.1 5.1 6.7 0.0 3.3 3 0 0 3 3 3 0 NTPase SRPRB PF09439.5 KND96844.1 - 0.0061 15.8 0.1 0.38 9.9 0.0 2.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Septin PF00735.13 KND96844.1 - 0.014 14.4 0.1 1.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Septin MMR_HSR1 PF01926.18 KND96844.1 - 0.014 15.3 0.6 0.74 9.7 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KND96844.1 - 0.015 14.8 0.2 3.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 KND96844.1 - 0.015 14.7 0.1 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KaiC PF06745.8 KND96844.1 - 0.019 14.1 0.3 1.2 8.1 0.0 3.1 4 0 0 4 4 3 0 KaiC AAA_5 PF07728.9 KND96844.1 - 0.019 14.6 0.1 6.4 6.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KND96844.1 - 0.026 13.5 0.0 0.64 9.0 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Miro PF08477.8 KND96844.1 - 0.027 14.9 1.3 1.7 9.1 0.0 3.2 4 0 0 4 4 2 0 Miro-like protein MobB PF03205.9 KND96844.1 - 0.033 13.8 0.8 4.1 7.1 0.0 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B Thymidylate_kin PF02223.12 KND96844.1 - 0.051 12.9 0.0 3.4 7.0 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase Ribonuc_red_2_N PF08471.5 KND96844.1 - 0.076 13.0 0.5 0.34 10.9 0.2 2.3 2 0 0 2 2 1 0 Class II vitamin B12-dependent ribonucleotide reductase Zeta_toxin PF06414.7 KND96844.1 - 0.14 11.2 0.0 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin DUF2075 PF09848.4 KND96844.1 - 0.17 10.8 0.7 2.5 6.9 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.12 KND96844.1 - 0.29 10.8 0.0 0.29 10.8 0.0 3.2 3 1 1 4 4 3 0 Domain of unknown function DUF87 Glutaredoxin PF00462.19 KND96846.1 - 7.7e-18 64.2 0.0 1.1e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Pkinase PF00069.20 KND96848.1 - 5.3e-71 238.8 0.0 7.2e-71 238.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND96848.1 - 1.4e-28 99.6 0.0 3.8e-28 98.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND96848.1 - 0.0002 20.4 0.8 0.15 10.9 0.0 2.6 2 1 1 3 3 3 2 Kinase-like YrbL-PhoP_reg PF10707.4 KND96848.1 - 0.12 11.6 2.7 0.62 9.3 0.7 2.4 2 1 0 2 2 2 0 PhoP regulatory network protein YrbL Nop14 PF04147.7 KND96848.1 - 2.1 6.1 15.5 2.9 5.6 10.8 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 KND96848.1 - 4.2 6.5 15.7 7.6 5.7 10.9 1.4 1 0 0 1 1 1 0 SDA1 SieB PF14163.1 KND96849.1 - 0.03 13.9 3.8 0.049 13.2 2.6 1.4 1 1 0 1 1 1 0 Superinfection exclusion protein B Ribosomal_L21p PF00829.16 KND96849.1 - 0.064 13.3 3.2 0.078 13.1 2.2 1.1 1 0 0 1 1 1 0 Ribosomal prokaryotic L21 protein BLVR PF06375.6 KND96849.1 - 1.2 8.9 8.3 1.3 8.8 5.7 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) ERK-JNK_inhib PF15002.1 KND96849.1 - 1.7 7.9 6.1 2.1 7.6 4.2 1.1 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor MARVEL PF01284.18 KND96851.1 - 0.026 14.3 0.0 0.027 14.3 0.0 1.0 1 0 0 1 1 1 0 Membrane-associating domain Npa1 PF11707.3 KND96852.1 - 4.4e-60 203.4 7.5 1e-59 202.1 4.9 1.9 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal Dam PF05869.6 KND96852.1 - 0.089 12.2 0.2 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) AAA_12 PF13087.1 KND96854.1 - 1e-60 204.5 0.1 3.6e-60 202.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KND96854.1 - 3.3e-53 180.6 0.0 6.6e-53 179.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND96854.1 - 1.1e-14 53.9 0.0 1.8e-11 43.6 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain Viral_helicase1 PF01443.13 KND96854.1 - 6.7e-09 35.6 0.1 0.0089 15.5 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KND96854.1 - 1e-08 35.0 0.0 4.9e-06 26.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KND96854.1 - 5.2e-06 26.5 0.1 1.5e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.11 KND96854.1 - 0.00015 21.0 0.0 0.014 14.6 0.0 2.7 3 0 0 3 3 2 1 PhoH-like protein Helicase_RecD PF05127.9 KND96854.1 - 0.00051 19.7 0.0 0.018 14.7 0.0 2.8 3 0 0 3 3 3 1 Helicase AAA_22 PF13401.1 KND96854.1 - 0.00054 20.1 0.1 0.0059 16.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain ResIII PF04851.10 KND96854.1 - 0.00062 19.6 0.0 0.011 15.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_23 PF13476.1 KND96854.1 - 0.00082 19.7 1.1 0.0016 18.7 0.2 2.1 2 1 0 2 2 1 1 AAA domain PIF1 PF05970.9 KND96854.1 - 0.00097 18.1 0.0 0.048 12.5 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase AAA_17 PF13207.1 KND96854.1 - 0.0016 19.2 0.0 0.0074 17.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 KND96854.1 - 0.0034 16.7 0.0 0.0071 15.6 0.0 1.7 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain FtsK_SpoIIIE PF01580.13 KND96854.1 - 0.004 16.6 0.0 0.014 14.8 0.0 1.9 2 0 0 2 2 1 1 FtsK/SpoIIIE family AAA PF00004.24 KND96854.1 - 0.0043 17.2 0.2 0.017 15.3 0.0 2.2 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KND96854.1 - 0.0049 16.6 0.0 0.18 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 KND96854.1 - 0.0053 15.7 0.0 0.013 14.5 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.1 KND96854.1 - 0.013 15.6 0.0 0.035 14.2 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_14 PF13173.1 KND96854.1 - 0.013 15.3 0.0 0.065 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KND96854.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KND96854.1 - 0.014 14.7 0.0 0.037 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KND96854.1 - 0.02 13.8 0.1 0.038 12.9 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RVT_3 PF13456.1 KND96854.1 - 0.031 14.0 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 1 0 Reverse transcriptase-like Arch_ATPase PF01637.13 KND96854.1 - 0.034 13.8 0.0 0.11 12.1 0.0 1.9 1 1 0 1 1 1 0 Archaeal ATPase Zot PF05707.7 KND96854.1 - 0.037 13.5 0.0 0.094 12.1 0.0 1.7 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) ABC_tran PF00005.22 KND96854.1 - 0.039 14.2 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 KND96854.1 - 0.083 12.4 0.0 0.51 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain CAP PF00188.21 KND96855.1 - 1.8e-21 76.9 5.1 3.2e-21 76.0 3.5 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF4588 PF15251.1 KND96855.1 - 0.017 15.1 2.8 0.023 14.6 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) MORN_2 PF07661.8 KND96855.1 - 0.14 12.2 0.2 65 4.0 0.0 3.2 3 0 0 3 3 3 0 MORN repeat variant Fungal_trans PF04082.13 KND96857.1 - 3.3e-17 62.2 0.1 5.6e-17 61.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND96857.1 - 8.3e-07 28.8 8.7 1.3e-06 28.1 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MSA_2 PF00985.12 KND96857.1 - 0.012 15.7 0.2 0.036 14.1 0.1 1.8 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Filament PF00038.16 KND96857.1 - 0.044 13.2 0.4 0.086 12.2 0.3 1.4 1 0 0 1 1 1 0 Intermediate filament protein Lipoprotein_20 PF13942.1 KND96857.1 - 0.054 13.0 3.1 0.38 10.2 0.2 2.3 2 0 0 2 2 2 0 YfhG lipoprotein Exonuc_VII_L PF02601.10 KND96858.1 - 0.62 9.2 6.5 0.93 8.6 4.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit PAT1 PF09770.4 KND96858.1 - 3.2 5.8 44.3 4.6 5.3 30.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ETF PF01012.16 KND96859.1 - 6.6e-37 126.7 0.8 1e-36 126.1 0.2 1.6 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 KND96859.1 - 1.6e-35 120.5 0.2 3e-35 119.7 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Sulfate_transp PF00916.15 KND96864.1 - 8.4e-48 162.7 0.8 1.4e-47 162.1 0.5 1.3 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 KND96864.1 - 1.4e-16 59.9 0.0 2.8e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain DUF1427 PF07235.6 KND96864.1 - 0.029 14.4 0.1 0.075 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1427) WD40 PF00400.27 KND96865.1 - 1.1e-26 91.7 12.2 2.2e-08 33.6 0.1 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KND96865.1 - 7.3e-24 83.4 0.4 1.4e-23 82.5 0.3 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex BING4CT PF08149.6 KND96865.1 - 0.083 12.4 0.0 4.7 6.7 0.0 3.3 4 0 0 4 4 4 0 BING4CT (NUC141) domain Acetyltransf_1 PF00583.19 KND96866.1 - 2.2e-10 40.3 0.0 3.3e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KND96866.1 - 2.1e-09 37.4 0.0 2.9e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KND96866.1 - 3e-05 23.9 0.0 4.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KND96866.1 - 0.00042 20.1 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain DUF4604 PF15377.1 KND96866.1 - 0.0012 19.0 0.9 0.0019 18.4 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Acetyltransf_10 PF13673.1 KND96866.1 - 0.0025 17.9 0.0 0.0044 17.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KND96866.1 - 0.0055 16.4 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein CENP-B_dimeris PF09026.5 KND96866.1 - 0.16 12.2 2.2 0.29 11.3 1.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2731 PF10806.3 KND96867.1 - 4.9e-27 94.6 0.0 8.5e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2731) DUF4218 PF13960.1 KND96867.1 - 0.0016 17.9 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) JAB PF01398.16 KND96868.1 - 4.3e-34 116.6 0.2 7.8e-34 115.8 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KND96868.1 - 2.6e-27 95.1 5.9 7.2e-27 93.7 3.9 1.9 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 KND96868.1 - 1.2e-08 34.3 0.0 1.9e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Peptidase_M24 PF00557.19 KND96870.1 - 1.3e-55 188.1 0.0 1.7e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KND96870.1 - 1.1e-22 79.8 0.2 3e-22 78.4 0.1 1.8 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain GDI PF00996.13 KND96871.1 - 1.8e-208 692.2 0.1 2.2e-208 691.9 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Asp_protease PF09668.5 KND96872.1 - 5.3e-41 139.0 0.0 7.6e-41 138.5 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 KND96872.1 - 4.3e-11 43.1 0.0 1.2e-10 41.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 KND96872.1 - 2.2e-10 39.7 0.0 4.6e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family gag-asp_proteas PF13975.1 KND96872.1 - 3.5e-10 39.5 0.0 7.9e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 KND96872.1 - 5.9e-08 32.5 0.0 1.2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 KND96872.1 - 2.9e-07 30.5 0.1 1.6e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease Rad60-SLD PF11976.3 KND96872.1 - 0.00018 21.1 0.0 0.00046 19.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KND96872.1 - 0.00021 21.4 0.0 0.00044 20.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain LSM PF01423.17 KND96873.1 - 2.4e-16 58.9 0.1 3.3e-16 58.5 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KND96873.1 - 0.0071 16.2 0.1 0.012 15.5 0.0 1.4 1 1 0 1 1 1 1 Ataxin 2 SM domain Response_reg PF00072.19 KND96874.1 - 5.6e-20 71.4 0.0 1.3e-13 50.9 0.0 2.3 1 1 1 2 2 2 2 Response regulator receiver domain BSD PF03909.12 KND96876.1 - 2e-15 56.2 2.6 2e-15 56.2 1.8 3.1 3 0 0 3 3 3 1 BSD domain NPV_P10 PF05531.7 KND96876.1 - 0.041 14.1 10.6 0.047 13.9 2.8 3.4 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1858 PF08984.6 KND96876.1 - 0.087 12.4 0.4 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1858) Lectin_N PF03954.9 KND96876.1 - 0.31 10.4 7.7 0.62 9.4 0.6 2.9 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Prominin PF05478.6 KND96876.1 - 0.32 8.4 7.0 0.29 8.6 3.7 1.5 1 1 0 1 1 1 0 Prominin DUF3080 PF11279.3 KND96876.1 - 0.42 9.7 8.3 0.73 8.9 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) Baculo_PEP_C PF04513.7 KND96876.1 - 0.42 10.4 10.5 4.7 7.0 2.8 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Allexi_40kDa PF05549.6 KND96876.1 - 1.2 8.3 9.7 0.11 11.7 1.2 2.3 2 1 2 4 4 4 0 Allexivirus 40kDa protein ABC2_membrane_3 PF12698.2 KND96876.1 - 1.4 7.8 4.0 1.8 7.5 2.7 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Med10 PF09748.4 KND96876.1 - 1.6 8.5 8.1 3.7 7.3 0.8 3.1 3 0 0 3 3 3 0 Transcription factor subunit Med10 of Mediator complex ABC_tran PF00005.22 KND96877.1 - 7.6e-22 78.0 0.1 1.8e-11 44.4 0.0 3.0 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 KND96877.1 - 2.3e-07 31.0 0.1 0.00085 19.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 KND96877.1 - 4.8e-06 26.3 0.0 0.1 12.4 0.0 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 KND96877.1 - 0.00041 20.5 0.2 1.8 8.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KND96877.1 - 0.13 11.6 0.1 3.7 6.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain Aminotran_1_2 PF00155.16 KND96878.1 - 4.4e-62 210.1 0.0 5.4e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KND96878.1 - 0.00017 20.8 0.0 0.00021 20.5 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Y_phosphatase2 PF03162.8 KND96879.1 - 2.3e-42 144.1 0.0 3e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Phage_glycop_gL PF11108.3 KND96879.1 - 0.033 14.1 0.1 0.052 13.5 0.1 1.4 1 1 0 1 1 1 0 Viral glycoprotein L COX7a PF02238.10 KND96879.1 - 0.097 12.4 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIa Y_phosphatase PF00102.22 KND96879.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase UCH PF00443.24 KND96880.1 - 1e-63 214.9 3.4 1.6e-63 214.3 2.4 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KND96880.1 - 7.8e-28 97.7 1.7 2.1e-27 96.3 1.1 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 KND96880.1 - 0.052 13.9 0.0 0.28 11.5 0.0 2.2 2 0 0 2 2 2 0 Rhodanese-like domain zf-MIZ PF02891.15 KND96880.1 - 0.064 12.7 0.5 0.15 11.6 0.3 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF3929 PF13066.1 KND96880.1 - 0.18 11.5 1.6 0.28 10.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3929) IF-2B PF01008.12 KND96881.1 - 5.8e-67 225.6 0.0 7.6e-67 225.2 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family UPF0052 PF01933.13 KND96882.1 - 2.8e-51 174.6 0.0 1.7e-50 172.0 0.0 2.0 1 1 0 1 1 1 1 Uncharacterised protein family UPF0052 WD40 PF00400.27 KND96883.1 - 2.4e-42 141.3 13.7 1.2e-10 40.8 0.7 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 KND96883.1 - 2.9e-05 22.4 3.6 0.034 12.2 0.1 3.2 1 1 1 3 3 3 2 Nucleoporin Nup120/160 WD40 PF00400.27 KND96885.1 - 3.6e-13 48.8 9.9 7.3e-05 22.4 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat Mur_ligase_M PF08245.7 KND96886.1 - 3.5e-06 27.1 1.0 2e-05 24.7 0.7 2.4 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 KND96886.1 - 0.0057 16.6 0.0 0.022 14.7 0.0 2.0 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain ERCC4 PF02732.10 KND96886.1 - 0.025 14.3 0.0 0.058 13.1 0.0 1.6 1 0 0 1 1 1 0 ERCC4 domain ANTAR PF03861.9 KND96886.1 - 0.049 13.2 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 ANTAR domain Med11 PF10280.4 KND96887.1 - 3.4e-27 94.7 0.4 5.1e-27 94.2 0.2 1.3 1 0 0 1 1 1 1 Mediator complex protein Sld5 PF05916.6 KND96888.1 - 1.4e-11 44.6 0.3 2e-11 44.1 0.2 1.2 1 0 0 1 1 1 1 GINS complex protein DUF2404 PF10296.4 KND96889.1 - 6.9e-05 22.8 0.0 0.0022 18.0 0.0 2.3 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) AAA PF00004.24 KND96890.1 - 3.4e-58 195.5 0.0 2.7e-43 147.3 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 KND96890.1 - 9.5e-21 73.6 0.1 3.1e-20 72.0 0.1 2.0 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 KND96890.1 - 2.7e-08 34.0 7.4 0.0074 16.2 0.3 4.4 3 2 1 4 4 3 2 AAA ATPase domain AAA_17 PF13207.1 KND96890.1 - 5.9e-08 33.5 0.0 0.024 15.4 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.1 KND96890.1 - 1e-07 31.5 3.5 0.39 10.0 0.1 4.2 2 2 2 4 4 4 3 AAA domain ABC_tran PF00005.22 KND96890.1 - 4.2e-07 30.3 2.7 0.00076 19.7 0.0 3.6 3 0 0 3 3 3 2 ABC transporter AAA_14 PF13173.1 KND96890.1 - 6.5e-07 29.3 0.4 0.077 12.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 KND96890.1 - 7.1e-07 29.0 8.4 0.0016 18.1 2.6 4.2 3 1 0 3 3 3 2 NACHT domain AAA_22 PF13401.1 KND96890.1 - 3.3e-06 27.2 8.7 0.021 14.9 0.8 4.5 3 2 1 4 4 4 3 AAA domain IstB_IS21 PF01695.12 KND96890.1 - 1.1e-05 24.8 0.1 0.13 11.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 KND96890.1 - 1.3e-05 25.5 0.4 0.15 12.3 0.0 3.5 3 1 0 3 3 2 2 AAA domain Viral_helicase1 PF01443.13 KND96890.1 - 3.4e-05 23.4 0.0 0.15 11.5 0.0 2.8 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 KND96890.1 - 4.6e-05 23.3 0.0 0.27 11.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 KND96890.1 - 5e-05 22.2 2.4 0.0073 15.1 0.0 2.9 3 0 0 3 3 3 2 NB-ARC domain RNA_helicase PF00910.17 KND96890.1 - 0.00011 22.3 0.1 1.2 9.3 0.0 3.3 3 0 0 3 3 2 2 RNA helicase AAA_2 PF07724.9 KND96890.1 - 0.00014 21.8 0.0 0.011 15.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KND96890.1 - 0.0002 21.0 0.0 0.76 9.5 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 KND96890.1 - 0.00088 19.0 4.1 0.2 11.3 0.0 4.2 3 2 1 4 4 3 1 Archaeal ATPase RuvB_N PF05496.7 KND96890.1 - 0.002 17.2 0.0 0.016 14.2 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 KND96890.1 - 0.0048 16.0 0.1 0.52 9.4 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 KND96890.1 - 0.0051 15.7 0.0 0.26 10.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 KND96890.1 - 0.0055 16.4 0.0 1.9 8.3 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 KND96890.1 - 0.0069 15.4 0.0 0.17 10.9 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin TIP49 PF06068.8 KND96890.1 - 0.007 15.1 0.0 0.21 10.2 0.0 2.4 2 0 0 2 2 2 1 TIP49 C-terminus AAA_28 PF13521.1 KND96890.1 - 0.013 15.4 0.0 4.3 7.2 0.0 2.8 3 0 0 3 3 2 0 AAA domain Sigma54_activat PF00158.21 KND96890.1 - 0.014 14.8 0.0 6.8 6.1 0.0 3.2 2 1 0 2 2 2 0 Sigma-54 interaction domain KaiC PF06745.8 KND96890.1 - 0.018 14.1 0.0 3.8 6.5 0.0 2.6 2 0 0 2 2 2 0 KaiC Torsin PF06309.6 KND96890.1 - 0.037 13.9 0.1 0.53 10.1 0.0 2.5 2 0 0 2 2 2 0 Torsin UPF0079 PF02367.12 KND96890.1 - 0.062 12.9 0.1 7.1 6.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 KND96890.1 - 0.32 10.3 3.6 0.84 9.0 0.1 2.9 3 0 0 3 3 3 0 AAA-like domain DUF3767 PF12597.3 KND96891.1 - 4.5e-41 139.2 0.0 6.8e-41 138.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DUF3353 PF11833.3 KND96891.1 - 0.4 10.1 2.4 0.4 10.1 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3353) DUF106 PF01956.11 KND96892.1 - 1.6e-08 34.2 0.0 1.6e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF106 DUF106 PF01956.11 KND96893.1 - 1.5e-31 109.1 2.9 2e-31 108.8 2.0 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 ATP_bind_1 PF03029.12 KND96894.1 - 9.5e-82 274.1 0.2 1.5e-81 273.4 0.2 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 KND96894.1 - 1.1e-08 34.7 0.5 2.2e-07 30.4 0.4 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 KND96894.1 - 8.5e-06 24.7 0.0 0.052 12.3 0.0 2.9 2 1 0 2 2 2 2 ArgK protein AAA_22 PF13401.1 KND96894.1 - 1.7e-05 24.9 0.0 8.8e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KND96894.1 - 2e-05 25.4 1.9 0.0003 21.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Arf PF00025.16 KND96894.1 - 2.9e-05 23.3 0.1 0.035 13.3 0.0 3.5 2 2 0 2 2 2 1 ADP-ribosylation factor family AAA_24 PF13479.1 KND96894.1 - 5e-05 22.9 0.0 0.00015 21.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KND96894.1 - 6.8e-05 22.7 0.0 0.00018 21.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 KND96894.1 - 0.00026 20.4 0.2 0.00069 19.0 0.0 1.8 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain FeoB_N PF02421.13 KND96894.1 - 0.00053 19.2 0.0 0.025 13.8 0.0 2.7 3 1 1 4 4 3 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 KND96894.1 - 0.00054 19.8 0.0 0.0015 18.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.2 KND96894.1 - 0.0014 18.1 1.5 0.01 15.3 1.0 2.1 1 1 0 1 1 1 1 AAA-like domain SRP54 PF00448.17 KND96894.1 - 0.0017 17.7 0.0 0.015 14.7 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NACHT PF05729.7 KND96894.1 - 0.0019 17.9 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KND96894.1 - 0.003 17.5 0.0 0.0064 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.4 KND96894.1 - 0.0034 16.8 0.0 0.085 12.3 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 KND96894.1 - 0.0078 16.7 0.0 6.9 7.2 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein SRPRB PF09439.5 KND96894.1 - 0.0095 15.1 0.0 0.58 9.3 0.0 2.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_18 PF13238.1 KND96894.1 - 0.011 16.0 4.7 0.023 14.9 0.0 3.0 2 1 1 3 3 3 0 AAA domain DUF87 PF01935.12 KND96894.1 - 0.016 15.0 0.3 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 APS_kinase PF01583.15 KND96894.1 - 0.023 14.3 0.0 0.057 13.0 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.17 KND96894.1 - 0.024 13.4 0.1 0.044 12.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF258 PF03193.11 KND96894.1 - 0.032 13.4 0.0 0.49 9.5 0.0 2.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 KND96894.1 - 0.036 13.6 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Glyco_tranf_2_3 PF13641.1 KND96894.1 - 0.041 13.6 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 MobB PF03205.9 KND96894.1 - 0.044 13.4 0.0 0.097 12.3 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 KND96894.1 - 0.05 13.1 0.1 0.69 9.3 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase G-alpha PF00503.15 KND96894.1 - 0.056 12.1 0.0 0.056 12.1 0.0 2.9 3 1 0 3 3 2 0 G-protein alpha subunit RNA_helicase PF00910.17 KND96894.1 - 0.064 13.4 0.2 0.66 10.1 0.0 2.7 3 0 0 3 3 3 0 RNA helicase cobW PF02492.14 KND96894.1 - 0.12 11.7 0.2 1.3 8.3 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF1237 PF06824.6 KND96895.1 - 9.7e-175 581.2 0.0 1.1e-174 580.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) TSC22 PF01166.13 KND96896.1 - 0.016 15.1 0.8 6.4 6.8 0.1 2.8 2 0 0 2 2 2 0 TSC-22/dip/bun family Methyltransf_16 PF10294.4 KND96897.1 - 1.3e-12 47.5 0.0 3.2e-11 43.0 0.0 2.0 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KND96897.1 - 6.6e-06 26.6 0.0 1.2e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND96897.1 - 0.0015 18.2 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND96897.1 - 0.096 13.1 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Antimicrobial_1 PF08018.6 KND96897.1 - 0.41 10.5 2.2 0.88 9.5 1.5 1.5 1 0 0 1 1 1 0 Frog antimicrobial peptide DUF202 PF02656.10 KND96898.1 - 9.8e-21 73.7 0.3 9.8e-21 73.7 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) CopD PF05425.8 KND96898.1 - 0.027 14.6 3.4 0.035 14.3 2.3 1.1 1 0 0 1 1 1 0 Copper resistance protein D MscS_TM PF12794.2 KND96898.1 - 0.073 11.6 2.4 0.083 11.4 1.7 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 MnhB PF04039.8 KND96898.1 - 0.12 12.3 4.5 0.17 11.9 3.1 1.3 1 1 0 1 1 1 0 Domain related to MnhB subunit of Na+/H+ antiporter Claudin_2 PF13903.1 KND96898.1 - 0.25 11.0 8.5 0.33 10.6 3.5 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF161 PF02588.10 KND96898.1 - 0.62 10.4 7.6 5.8 7.3 4.7 2.4 1 1 0 1 1 1 0 Uncharacterized BCR, YitT family COG1284 DUF1469 PF07332.6 KND96898.1 - 0.8 9.4 6.0 1 9.1 3.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) Arif-1 PF06770.6 KND96898.1 - 1 8.7 4.1 1.3 8.3 2.8 1.3 1 1 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) DUF3784 PF12650.2 KND96898.1 - 1.6 8.6 5.7 1.4 8.8 3.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) DUF4131 PF13567.1 KND96898.1 - 5 6.4 7.9 2.4 7.5 0.9 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) SdpI PF13630.1 KND96898.1 - 5.8 6.6 7.0 2.6 7.8 2.9 1.8 2 0 0 2 2 2 0 SdpI/YhfL protein family Tetraspannin PF00335.15 KND96898.1 - 9.5 5.4 10.6 16 4.6 7.3 1.4 1 1 0 1 1 1 0 Tetraspanin family Coa1 PF08695.5 KND96900.1 - 0.75 9.3 3.4 7.4 6.0 0.0 2.4 1 1 1 2 2 2 0 Cytochrome oxidase complex assembly protein 1 Mucin PF01456.12 KND96900.1 - 6.1 6.6 15.9 7.5 6.3 11.0 1.3 1 1 0 1 1 1 0 Mucin-like glycoprotein Metallophos PF00149.23 KND96902.1 - 0.03 13.7 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase MCM PF00493.18 KND96903.1 - 1.1e-137 458.2 0.1 1.6e-137 457.8 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 KND96903.1 - 4.5e-35 120.9 31.1 4.5e-35 120.9 21.6 2.5 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 KND96903.1 - 9.9e-16 58.3 0.1 2.7e-15 56.9 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KND96903.1 - 3.6e-08 32.8 0.0 2.4e-06 26.8 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KND96903.1 - 7.3e-07 29.0 0.0 1.8e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KND96903.1 - 0.00045 19.8 0.0 0.0089 15.6 0.0 2.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KND96903.1 - 0.0022 17.5 0.1 0.011 15.1 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain DUF4456 PF14644.1 KND96903.1 - 0.016 14.4 0.3 0.032 13.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) RNA_POL_M_15KD PF02150.11 KND96903.1 - 0.22 11.2 1.1 0.41 10.3 0.7 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit zf-UBR PF02207.15 KND96904.1 - 5.3e-15 54.8 5.3 5.3e-15 54.8 3.7 2.0 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Lon_C PF05362.8 KND96905.1 - 1.2e-61 207.5 0.0 3e-61 206.3 0.0 1.7 2 0 0 2 2 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KND96905.1 - 4.4e-25 88.5 4.3 1.4e-24 86.9 0.0 2.8 3 0 0 3 3 3 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KND96905.1 - 3.9e-21 75.6 1.6 2.3e-20 73.1 0.0 2.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KND96905.1 - 2e-07 30.8 0.0 4.7e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.6 KND96905.1 - 7.2e-07 28.2 0.1 6.1e-06 25.1 0.0 2.1 2 0 0 2 2 2 1 PrkA AAA domain RuvB_N PF05496.7 KND96905.1 - 1.1e-06 27.8 0.0 3.6e-05 22.9 0.0 2.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KND96905.1 - 3.1e-06 27.3 0.1 9e-05 22.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KND96905.1 - 7.3e-06 26.7 0.0 3.1e-05 24.7 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KND96905.1 - 1.1e-05 25.5 1.6 0.00094 19.3 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 KND96905.1 - 1.3e-05 25.1 0.0 5e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 KND96905.1 - 2.7e-05 23.8 0.1 7e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KND96905.1 - 0.00011 22.0 0.3 0.0003 20.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.8 KND96905.1 - 0.00014 20.6 0.2 0.0033 16.2 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus NTPase_1 PF03266.10 KND96905.1 - 0.00018 21.2 0.1 0.0055 16.4 0.0 2.5 1 1 1 2 2 2 1 NTPase AAA_18 PF13238.1 KND96905.1 - 0.00056 20.2 1.8 0.002 18.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain ChlI PF13541.1 KND96905.1 - 0.00071 19.0 0.0 0.0017 17.8 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase IstB_IS21 PF01695.12 KND96905.1 - 0.0009 18.7 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_11 PF13086.1 KND96905.1 - 0.0033 17.0 1.0 0.2 11.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KND96905.1 - 0.0045 16.0 0.2 0.016 14.3 0.0 1.9 2 0 0 2 2 1 1 Zeta toxin UPF0079 PF02367.12 KND96905.1 - 0.0081 15.7 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 KND96905.1 - 0.013 15.1 0.7 0.026 14.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 KND96905.1 - 0.013 14.6 0.0 0.23 10.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KND96905.1 - 0.015 14.9 0.0 0.1 12.2 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 KND96905.1 - 0.023 14.5 0.0 0.068 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 KND96905.1 - 0.024 13.5 0.0 0.058 12.2 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.1 KND96905.1 - 0.026 13.9 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KND96905.1 - 0.026 14.1 0.0 0.073 12.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KND96905.1 - 0.037 13.9 0.8 0.072 13.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 KND96905.1 - 0.045 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 KND96905.1 - 0.18 12.1 0.1 0.18 12.1 0.1 2.8 2 1 0 2 2 2 0 ABC transporter APG17 PF04108.7 KND96906.1 - 0.0032 16.3 0.5 0.0048 15.7 0.4 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 HCR PF07111.7 KND96906.1 - 0.0047 14.9 1.1 0.0073 14.3 0.7 1.2 1 0 0 1 1 1 1 Alpha helical coiled-coil rod protein (HCR) Pox_A_type_inc PF04508.7 KND96906.1 - 0.0053 16.4 6.4 0.045 13.5 0.3 3.7 3 0 0 3 3 3 1 Viral A-type inclusion protein repeat FlxA PF14282.1 KND96906.1 - 0.01 15.7 1.7 0.2 11.6 0.1 2.8 3 0 0 3 3 3 0 FlxA-like protein DUF4404 PF14357.1 KND96906.1 - 0.038 14.4 1.8 0.058 13.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) TMF_DNA_bd PF12329.3 KND96906.1 - 0.85 9.4 4.4 0.31 10.8 0.5 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Lzipper-MIP1 PF14389.1 KND96906.1 - 1.6 8.8 6.2 3.9 7.6 1.7 3.0 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 UAF_Rrn10 PF05234.6 KND96907.1 - 1.6e-05 24.9 0.2 5.4e-05 23.1 0.1 2.0 1 1 0 1 1 1 1 UAF complex subunit Rrn10 TEX19 PF15553.1 KND96907.1 - 7.7 6.3 9.1 1.8 8.4 3.4 1.9 1 1 1 2 2 2 0 Testis-expressed protein 19 Nol1_Nop2_Fmu PF01189.12 KND96908.1 - 4.2e-58 196.9 0.0 4.8e-45 154.1 0.0 2.2 1 1 1 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 KND96908.1 - 0.012 15.6 0.0 0.031 14.2 0.0 1.7 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KND96908.1 - 0.016 15.2 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain zf-RING_2 PF13639.1 KND96909.1 - 4.5e-12 45.5 6.3 4.5e-12 45.5 4.3 1.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KND96909.1 - 3.3e-09 36.7 1.5 3.3e-09 36.7 1.1 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KND96909.1 - 1.3e-07 31.5 4.6 2.7e-07 30.4 3.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KND96909.1 - 2.9e-07 30.0 3.7 4.9e-07 29.3 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KND96909.1 - 1.7e-06 27.5 2.7 3.3e-06 26.6 1.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND96909.1 - 1.4e-05 24.6 1.9 2.5e-05 23.8 1.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KND96909.1 - 0.0016 18.2 1.1 0.003 17.3 0.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KND96909.1 - 0.068 12.7 2.3 0.21 11.1 1.6 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 KND96909.1 - 0.12 12.4 0.8 0.24 11.4 0.6 1.5 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 KND96909.1 - 0.17 11.8 4.9 1.5 8.8 3.4 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain CBFD_NFYB_HMF PF00808.18 KND96910.1 - 1.9e-25 88.6 0.1 3.6e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KND96910.1 - 4.7e-06 26.6 0.0 8.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KND96910.1 - 0.026 14.2 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-18kDa PF02269.11 KND96910.1 - 0.026 14.3 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Phosphoprotein PF00922.12 KND96910.1 - 0.17 11.0 5.1 0.28 10.3 3.5 1.4 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Rft-1 PF04506.8 KND96911.1 - 1.6e-78 264.4 36.7 4.3e-78 263.0 25.4 1.5 1 1 0 1 1 1 1 Rft protein Snapin_Pallidin PF14712.1 KND96912.1 - 0.0097 16.1 1.9 0.011 15.9 0.4 1.7 2 0 0 2 2 2 1 Snapin/Pallidin C1_1 PF00130.17 KND96912.1 - 0.058 13.1 3.3 0.11 12.2 0.4 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HWE_HK PF07536.9 KND96912.1 - 0.081 13.3 1.0 0.36 11.2 0.3 2.2 1 1 1 2 2 2 0 HWE histidine kinase zf-CCHC PF00098.18 KND96912.1 - 4.7 7.3 7.2 0.41 10.6 1.4 1.9 2 0 0 2 2 2 0 Zinc knuckle LSM PF01423.17 KND96913.1 - 1.8e-14 53.0 0.7 2.2e-14 52.7 0.5 1.1 1 0 0 1 1 1 1 LSM domain DUF1461 PF07314.6 KND96913.1 - 0.034 13.8 0.1 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) NDT80_PhoG PF05224.7 KND96914.1 - 4.6e-32 111.5 0.0 1.5e-31 109.8 0.0 1.8 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family GNAT_acetyltr_2 PF13718.1 KND96915.1 - 1.4e-80 269.3 0.0 2.9e-80 268.2 0.0 1.6 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 KND96915.1 - 2.2e-66 222.8 0.0 1.8e-65 219.9 0.0 2.5 2 1 0 2 2 2 1 Helicase DUF1726 PF08351.6 KND96915.1 - 8.5e-40 134.3 0.5 3.3e-39 132.4 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 KND96915.1 - 2.1e-38 130.4 1.2 1e-37 128.3 0.8 2.2 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 KND96915.1 - 0.0022 18.1 0.0 0.012 15.7 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_22 PF13401.1 KND96915.1 - 0.037 14.1 0.0 2 8.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain Acetyltransf_1 PF00583.19 KND96915.1 - 0.045 13.7 0.0 0.18 11.8 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family AAA_17 PF13207.1 KND96916.1 - 7.5e-09 36.4 0.1 4.4e-08 33.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 KND96916.1 - 4.8e-08 32.7 0.0 9.4e-08 31.8 0.0 1.5 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 KND96916.1 - 3e-07 30.7 0.1 1.1e-06 28.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 KND96916.1 - 0.0017 17.9 0.0 0.0038 16.8 0.0 1.9 1 1 1 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.1 KND96916.1 - 0.0055 16.6 1.1 0.045 13.7 0.1 2.3 1 1 0 2 2 2 1 AAA domain MobB PF03205.9 KND96916.1 - 0.021 14.5 0.1 0.28 10.8 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KND96916.1 - 0.024 14.5 0.0 0.052 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 KND96916.1 - 0.033 14.4 0.2 0.089 13.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KND96916.1 - 0.036 13.9 0.0 0.062 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KND96916.1 - 0.036 13.1 0.0 0.072 12.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.5 KND96916.1 - 0.04 13.1 0.0 0.051 12.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF3987 PF13148.1 KND96916.1 - 0.064 11.8 0.3 4.1 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_30 PF13604.1 KND96916.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2722 PF10846.3 KND96918.1 - 4.4e-17 62.2 6.2 7.1e-14 51.6 0.0 2.7 2 1 0 3 3 3 2 Protein of unknown function (DUF2722) BLVR PF06375.6 KND96919.1 - 3.8 7.3 7.8 3.8 7.3 5.4 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) TAF1D PF15333.1 KND96919.1 - 4.5 6.9 8.0 4.7 6.9 5.5 1.0 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D DUF2897 PF11446.3 KND96919.1 - 5 7.0 5.9 6.2 6.7 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Protocadherin PF08374.6 KND96919.1 - 5.7 6.5 5.9 5.2 6.6 4.1 1.1 1 0 0 1 1 1 0 Protocadherin AA_permease_2 PF13520.1 KND96920.1 - 2.4e-62 210.8 39.5 3e-62 210.5 27.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KND96920.1 - 2.1e-14 52.7 34.5 3.2e-14 52.1 23.9 1.2 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 KND96921.1 - 8.1e-35 120.1 35.2 8.6e-31 106.9 14.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KND96921.1 - 0.012 13.6 3.6 0.039 12.0 0.1 2.6 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Snf7 PF03357.16 KND96922.1 - 2.3e-43 147.5 11.0 2.5e-43 147.4 7.6 1.0 1 0 0 1 1 1 1 Snf7 Prefoldin_2 PF01920.15 KND96922.1 - 0.0013 18.4 14.0 0.079 12.7 0.0 3.1 2 1 0 2 2 2 1 Prefoldin subunit Seryl_tRNA_N PF02403.17 KND96922.1 - 0.0014 18.5 12.1 0.011 15.7 2.5 2.4 2 1 0 2 2 2 2 Seryl-tRNA synthetase N-terminal domain DUF1411 PF07199.6 KND96922.1 - 0.021 14.2 0.8 0.03 13.7 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1411) Mnd1 PF03962.10 KND96922.1 - 0.074 12.7 10.7 0.65 9.6 7.4 2.0 1 1 0 1 1 1 0 Mnd1 family Exonuc_VII_L PF02601.10 KND96922.1 - 0.096 11.8 6.1 0.12 11.5 4.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_13 PF13166.1 KND96922.1 - 0.17 10.3 9.7 0.31 9.4 6.7 1.4 1 1 0 1 1 1 0 AAA domain Tropomyosin_1 PF12718.2 KND96922.1 - 0.19 11.5 16.3 0.028 14.2 5.1 2.3 1 1 1 2 2 2 0 Tropomyosin like DUF1395 PF07160.7 KND96922.1 - 0.26 10.7 7.2 0.52 9.7 4.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1395) PspA_IM30 PF04012.7 KND96922.1 - 0.31 10.3 9.4 0.42 9.9 5.0 1.9 1 1 0 2 2 2 0 PspA/IM30 family Phage_GP20 PF06810.6 KND96922.1 - 0.71 9.3 20.3 4.8 6.6 14.1 2.4 1 1 0 1 1 1 0 Phage minor structural protein GP20 OmpH PF03938.9 KND96922.1 - 0.72 9.7 11.4 1.6 8.6 2.7 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) NPV_P10 PF05531.7 KND96922.1 - 0.86 9.8 11.7 1.6 9.0 0.0 3.4 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Prefoldin PF02996.12 KND96922.1 - 0.9 9.2 0.0 0.9 9.2 0.0 3.5 2 1 0 3 3 3 0 Prefoldin subunit COG2 PF06148.6 KND96922.1 - 1.2 9.0 6.6 3.5 7.4 2.1 2.6 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.6 KND96922.1 - 1.5 8.7 9.9 1.6 8.6 0.1 3.7 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF342 PF03961.8 KND96922.1 - 1.6 7.0 12.3 0.5 8.7 5.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF2802 PF10975.3 KND96922.1 - 1.8 8.3 5.6 0.63 9.8 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2802) IZUMO PF15005.1 KND96922.1 - 2 8.4 6.2 2.4 8.1 3.9 1.4 1 1 0 1 1 1 0 Izumo sperm-egg fusion TBPIP PF07106.8 KND96922.1 - 2.1 7.8 16.7 0.44 10.0 3.6 2.6 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SlyX PF04102.7 KND96922.1 - 4.6 7.6 11.2 35 4.8 0.3 3.6 2 2 1 3 3 3 0 SlyX GrpE PF01025.14 KND96922.1 - 9.8 5.6 9.1 15 5.0 4.9 2.1 1 1 2 3 3 3 0 GrpE MFS_1 PF07690.11 KND96927.1 - 8.1e-38 130.0 17.9 8.1e-38 130.0 12.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND96927.1 - 6.3e-14 51.4 11.3 8.9e-14 50.9 7.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter CD4-extracel PF09191.5 KND96931.1 - 1.2 9.1 6.1 1.7 8.7 4.2 1.3 1 1 0 1 1 1 0 CD4, extracellular Colicin_C PF12106.3 KND96932.1 - 0.013 15.0 16.3 0.31 10.6 4.7 3.8 2 2 0 2 2 2 0 Colicin C terminal ribonuclease domain PPV_E2_C PF00511.12 KND96933.1 - 6.3e-13 48.4 96.1 0.41 10.6 0.3 18.0 3 2 14 18 18 18 8 E2 (early) protein, C terminal Imm33 PF15580.1 KND96933.1 - 3.8e-10 39.1 37.9 15 5.1 0.0 16.0 18 0 0 18 18 18 2 Immunity protein 33 FTP PF07504.8 KND96933.1 - 4.2e-10 38.9 94.5 0.4 10.1 0.2 19.6 20 0 0 20 20 20 10 Fungalysin/Thermolysin Propeptide Motif TFIIIC_delta PF12657.2 KND96933.1 - 0.00054 19.7 29.5 0.11 12.1 0.7 6.8 2 1 3 6 6 6 4 Transcription factor IIIC subunit delta N-term RNase_P_pop3 PF08228.6 KND96933.1 - 0.00065 19.5 1.9 1.5e+02 2.1 0.0 7.3 8 0 0 8 8 8 0 RNase P subunit Pop3 FlgD_ig PF13860.1 KND96933.1 - 0.0011 18.6 81.8 1.6 8.4 0.2 15.6 3 2 12 15 15 15 5 FlgD Ig-like domain DUF3872 PF12988.2 KND96933.1 - 0.024 14.1 0.0 2.4e+02 1.2 0.0 6.2 8 1 0 8 8 8 0 Domain of unknown function, B. Theta Gene description (DUF3872) GGDEF PF00990.16 KND96933.1 - 0.15 11.6 1.2 1.9e+02 1.5 0.0 4.5 2 1 5 7 7 7 0 GGDEF domain Rotamase_3 PF13616.1 KND96933.1 - 1.5 9.1 16.9 83 3.4 0.0 8.6 3 2 10 13 13 13 0 PPIC-type PPIASE domain Mannosyl_trans3 PF11051.3 KND96934.1 - 9.5e-59 198.9 0.0 1.3e-58 198.4 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Amidase PF01425.16 KND96935.1 - 1.6e-93 314.0 0.0 1.9e-93 313.7 0.0 1.1 1 0 0 1 1 1 1 Amidase SSF PF00474.12 KND96936.1 - 2.1e-19 69.4 25.1 2.1e-19 69.4 17.4 2.2 2 0 0 2 2 2 1 Sodium:solute symporter family Asp PF00026.18 KND96937.1 - 1.1e-67 228.5 2.3 1.3e-67 228.3 1.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KND96937.1 - 0.0004 20.3 0.1 0.0011 18.9 0.1 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KND96937.1 - 0.0028 18.0 0.1 7.2 7.1 0.0 3.7 2 2 0 2 2 2 2 Aspartyl protease MFS_1 PF07690.11 KND96938.1 - 0.12 11.0 13.3 0.29 9.7 9.2 1.7 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF2306 PF10067.4 KND96938.1 - 1.3 9.1 10.0 0.66 10.1 0.8 2.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2306) p450 PF00067.17 KND96940.1 - 1.2e-45 155.9 0.0 1.5e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Amidohydro_1 PF01979.15 KND96942.1 - 4.8e-34 118.4 0.0 6.2e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KND96942.1 - 6.6e-05 22.3 0.2 0.0059 15.8 0.0 2.8 2 1 0 3 3 3 1 Amidohydrolase family Amidohydro_5 PF13594.1 KND96942.1 - 0.027 14.2 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 Amidohydrolase Fungal_trans_2 PF11951.3 KND96943.1 - 3.6e-22 78.4 1.7 1.1e-21 76.9 1.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Amidase PF01425.16 KND96945.1 - 1.6e-87 294.1 0.0 2e-87 293.9 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF1857 PF08982.6 KND96945.1 - 0.029 13.9 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) Lectin_leg-like PF03388.8 KND96948.1 - 6.6e-14 51.5 0.1 1e-13 50.9 0.1 1.2 1 0 0 1 1 1 1 Legume-like lectin family SpecificRecomb PF10136.4 KND96948.1 - 0.21 9.5 1.7 0.3 9.0 1.2 1.1 1 0 0 1 1 1 0 Site-specific recombinase P12 PF12669.2 KND96948.1 - 0.96 9.7 3.0 1.6 8.9 2.1 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family muHD PF10291.4 KND96949.1 - 1.9e-55 187.8 0.1 3.7e-55 186.9 0.1 1.5 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Ammonium_transp PF00909.16 KND96951.1 - 5.3e-92 308.3 19.2 6.1e-92 308.1 13.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family UPF0183 PF03676.9 KND96953.1 - 2e-31 108.9 0.1 3.4e-18 65.4 0.0 3.8 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) LRR_9 PF14580.1 KND96954.1 - 2.9e-30 105.0 1.1 3.7e-30 104.7 0.7 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 KND96954.1 - 2.4e-05 23.8 15.2 0.0072 15.9 1.2 3.7 2 2 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KND96954.1 - 0.12 12.2 14.3 0.029 14.1 5.0 3.0 1 1 1 2 2 2 0 Leucine rich repeat LRR_1 PF00560.28 KND96954.1 - 0.13 12.3 12.5 9.1 6.7 0.2 5.3 3 1 1 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 KND96954.1 - 7.9 7.1 8.5 8.1 7.1 0.3 4.3 4 1 0 4 4 4 0 Leucine rich repeat PHD PF00628.24 KND96955.1 - 2.2e-14 52.8 63.7 1.1e-07 31.4 6.3 6.7 7 1 0 7 7 7 3 PHD-finger BAH PF01426.13 KND96955.1 - 1.3e-11 44.2 0.0 3.8e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 BAH domain PHD_2 PF13831.1 KND96955.1 - 7.4e-07 28.3 2.5 7.4e-07 28.3 1.8 4.3 4 0 0 4 4 4 2 PHD-finger zf-HC5HC2H PF13771.1 KND96955.1 - 1.3e-06 28.4 2.3 1.3e-06 28.4 1.6 6.1 6 1 1 7 7 7 1 PHD-like zinc-binding domain mRNA_cap_enzyme PF01331.14 KND96956.1 - 2.8e-60 203.2 0.0 4.7e-60 202.5 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 KND96956.1 - 7.9e-24 83.9 0.8 1.5e-23 83.1 0.2 1.8 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 KND96956.1 - 4.9e-09 35.8 0.0 6e-07 29.0 0.0 2.8 2 1 0 2 2 2 1 ATP dependent DNA ligase domain Spot_14 PF07084.7 KND96956.1 - 0.017 14.9 0.2 0.017 14.9 0.1 1.5 2 0 0 2 2 2 0 Thyroid hormone-inducible hepatic protein Spot 14 Prefoldin_2 PF01920.15 KND96957.1 - 4.2e-19 68.2 10.2 4.9e-19 68.0 7.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit DivIC PF04977.10 KND96957.1 - 0.00023 20.5 10.4 0.019 14.4 1.9 2.2 2 0 0 2 2 2 2 Septum formation initiator Ribosomal_S15 PF00312.17 KND96957.1 - 0.0049 16.5 1.0 0.0095 15.6 0.1 1.9 2 1 0 2 2 2 1 Ribosomal protein S15 FliD_C PF07195.7 KND96957.1 - 0.011 15.0 1.6 0.014 14.7 0.2 1.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Pro_dh PF01619.13 KND96957.1 - 0.036 13.0 1.4 0.041 12.8 1.0 1.1 1 0 0 1 1 1 0 Proline dehydrogenase DUF4600 PF15372.1 KND96957.1 - 0.061 13.5 5.1 0.51 10.5 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) Prefoldin PF02996.12 KND96957.1 - 0.14 11.8 8.1 1 9.0 5.6 2.0 1 1 0 1 1 1 0 Prefoldin subunit Phage_GP20 PF06810.6 KND96957.1 - 0.18 11.2 12.2 0.75 9.2 0.6 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 NPV_P10 PF05531.7 KND96957.1 - 0.19 11.9 3.4 6.8 7.0 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein bZIP_1 PF00170.16 KND96957.1 - 0.26 11.2 6.3 2.3 8.2 0.1 2.7 2 1 0 2 2 2 0 bZIP transcription factor Snapin_Pallidin PF14712.1 KND96957.1 - 0.32 11.3 4.9 1.8 8.9 0.1 2.1 2 0 0 2 2 2 0 Snapin/Pallidin FlxA PF14282.1 KND96957.1 - 0.42 10.5 6.1 0.87 9.5 0.1 2.2 2 0 0 2 2 2 0 FlxA-like protein DUF904 PF06005.7 KND96957.1 - 0.48 10.7 7.7 34 4.8 5.3 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Atg14 PF10186.4 KND96957.1 - 0.54 9.1 2.8 0.87 8.4 1.9 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FlaC_arch PF05377.6 KND96957.1 - 0.81 9.6 4.4 2 8.3 0.1 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.1 KND96957.1 - 0.97 9.9 4.0 11 6.4 0.2 2.1 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Med4 PF10018.4 KND96957.1 - 0.99 8.7 5.8 0.54 9.6 1.2 2.0 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 His_kinase PF06580.8 KND96957.1 - 1.1 9.2 5.6 1.9 8.4 0.2 2.2 2 0 0 2 2 2 0 Histidine kinase HALZ PF02183.13 KND96957.1 - 1.1 9.0 6.4 11 5.8 1.4 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper TSC22 PF01166.13 KND96957.1 - 2.3 8.2 7.7 0.85 9.6 0.3 2.6 2 1 0 2 2 2 0 TSC-22/dip/bun family DUF342 PF03961.8 KND96957.1 - 3.1 6.1 7.8 6.2 5.1 5.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Acetyltransf_7 PF13508.1 KND96958.1 - 8.6e-06 25.8 0.0 3.8e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KND96958.1 - 1e-05 25.3 0.0 3e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KND96958.1 - 0.0011 18.9 0.0 0.0056 16.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KND96958.1 - 0.0077 16.4 0.0 0.026 14.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KND96958.1 - 0.014 15.1 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein Homeobox_KN PF05920.6 KND96962.1 - 2.4e-16 59.1 1.1 5.3e-16 58.0 0.7 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KND96962.1 - 1.7e-05 24.3 1.1 2.7e-05 23.6 0.7 1.4 1 0 0 1 1 1 1 Homeobox domain Exo70 PF03081.10 KND96964.1 - 2e-68 230.8 2.9 2e-68 230.8 2.0 1.9 2 0 0 2 2 2 1 Exo70 exocyst complex subunit DUF1068 PF06364.7 KND96964.1 - 0.21 11.2 5.4 0.038 13.5 0.5 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1068) RNA_lig_T4_1 PF09511.5 KND96965.1 - 8.5e-70 234.6 1.0 1.7e-69 233.6 0.7 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 KND96965.1 - 2.3e-39 134.9 0.1 1.7e-38 132.0 0.0 2.4 2 0 0 2 2 2 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 KND96965.1 - 1.5e-35 122.6 0.4 3.1e-35 121.6 0.3 1.5 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 KND96966.1 - 2.3e-27 95.8 0.4 4.2e-27 95.0 0.3 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain PglZ PF08665.7 KND96966.1 - 0.0014 18.3 0.1 0.0039 16.8 0.0 1.7 2 0 0 2 2 2 1 PglZ domain Tenui_N PF05733.6 KND96966.1 - 0.035 13.4 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 Tenuivirus/Phlebovirus nucleocapsid protein KTI12 PF08433.5 KND96966.1 - 0.054 12.7 0.0 0.067 12.3 0.0 1.3 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Fumble PF03630.9 KND96969.1 - 7.4e-116 386.7 1.0 2.2e-115 385.1 0.7 1.7 1 1 0 1 1 1 1 Fumble PEX11 PF05648.9 KND96970.1 - 7.4e-08 31.9 1.9 0.0011 18.3 0.4 2.3 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) PALP PF00291.20 KND96971.1 - 3.9e-54 183.9 0.0 4.5e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Nop25 PF09805.4 KND96973.1 - 0.99 9.4 5.8 1.2 9.1 4.1 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) ING PF12998.2 KND96974.1 - 3e-22 78.9 7.6 3e-22 78.9 5.3 1.5 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KND96974.1 - 8.2e-10 38.2 8.3 1.3e-09 37.5 5.7 1.4 1 0 0 1 1 1 1 PHD-finger GAPT PF11770.3 KND96974.1 - 0.023 14.3 0.1 0.053 13.1 0.0 1.6 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) zf-HC5HC2H PF13771.1 KND96974.1 - 0.055 13.6 0.2 0.055 13.6 0.2 1.7 2 0 0 2 2 2 0 PHD-like zinc-binding domain PHD_2 PF13831.1 KND96974.1 - 0.064 12.5 2.7 0.11 11.7 1.9 1.4 1 0 0 1 1 1 0 PHD-finger PhnA_Zn_Ribbon PF08274.7 KND96974.1 - 0.26 11.0 3.2 2.1 8.1 0.3 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-RING-like PF08746.6 KND96974.1 - 0.44 10.5 2.9 0.77 9.8 2.0 1.4 1 0 0 1 1 1 0 RING-like domain zf-C4_Topoisom PF01396.14 KND96974.1 - 4.2 6.9 7.6 6 6.4 0.8 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger DUF2681 PF10883.3 KND96978.1 - 0.063 13.4 1.6 0.079 13.1 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Kri1 PF05178.7 KND96978.1 - 0.6 10.4 5.7 0.72 10.1 4.0 1.1 1 0 0 1 1 1 0 KRI1-like family Fungal_trans PF04082.13 KND96979.1 - 2.4e-28 98.7 0.1 4.8e-28 97.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND96979.1 - 2.4e-09 36.9 9.6 3.7e-09 36.3 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zip PF02535.17 KND96979.1 - 0.02 13.8 5.2 1 8.2 0.9 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter Pept_tRNA_hydro PF01195.14 KND96981.1 - 4.5e-31 107.7 0.1 5.5e-31 107.4 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase DUF3336 PF11815.3 KND96982.1 - 2.5e-46 156.7 4.0 5.3e-46 155.7 2.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KND96982.1 - 3.4e-17 63.0 0.1 1.3e-16 61.1 0.0 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase Reticulon PF02453.12 KND96982.1 - 0.086 12.4 0.1 0.086 12.4 0.0 1.8 2 0 0 2 2 2 0 Reticulon AgrB PF04647.10 KND96982.1 - 0.11 11.5 3.1 0.26 10.3 0.1 2.2 2 0 0 2 2 2 0 Accessory gene regulator B E1_dh PF00676.15 KND96983.1 - 0.068 11.8 0.0 0.077 11.6 0.0 1.1 1 0 0 1 1 1 0 Dehydrogenase E1 component HAD_2 PF13419.1 KND96985.1 - 2.5e-18 66.9 0.0 3.5e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase PA PF02225.17 KND96985.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 PA domain UBA PF00627.26 KND96986.1 - 1.6e-19 69.0 3.2 4.2e-10 39.1 0.1 2.7 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.6 KND96986.1 - 2.5e-18 65.2 1.8 4e-18 64.6 0.3 1.9 2 0 0 2 2 2 1 XPC-binding domain WIYLD PF10440.4 KND96986.1 - 0.0067 16.3 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin-binding WIYLD domain DUF2397 PF09660.5 KND96986.1 - 0.0073 14.9 1.0 0.01 14.4 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2397) UBA_3 PF09288.5 KND96986.1 - 0.027 14.0 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Rap1_C PF11626.3 KND96986.1 - 0.034 14.0 0.0 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF4607 PF15380.1 KND96986.1 - 1.4 8.3 10.4 0.27 10.6 3.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4607) DUF3020 PF11223.3 KND96987.1 - 2.5e-20 72.6 7.5 2.5e-20 72.6 5.2 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3020) DUF1667 PF07892.6 KND96987.1 - 0.24 11.1 2.2 17 5.1 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1667) Peptidase_M24 PF00557.19 KND96988.1 - 6.3e-31 107.5 0.0 1e-30 106.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KND96988.1 - 3.8e-15 56.5 0.0 2.8e-12 47.2 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain SMC_N PF02463.14 KND96989.1 - 5.5e-65 218.6 0.0 1.5e-64 217.2 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KND96989.1 - 2e-27 95.5 1.6 5.3e-27 94.1 0.2 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KND96989.1 - 4e-11 43.4 31.8 0.00019 21.5 3.8 4.7 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KND96989.1 - 3.4e-07 29.6 0.1 7.3e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KND96989.1 - 0.00097 19.5 47.7 0.00097 19.5 33.1 6.6 2 2 2 4 4 4 1 AAA domain APG6 PF04111.7 KND96989.1 - 0.0029 16.6 7.6 0.0029 16.6 5.2 6.6 4 1 3 7 7 7 2 Autophagy protein Apg6 ABC_tran PF00005.22 KND96989.1 - 0.1 12.8 0.1 0.1 12.8 0.0 5.4 4 3 0 4 4 4 0 ABC transporter Reo_sigmaC PF04582.7 KND96989.1 - 1.1 8.3 26.1 0.49 9.5 2.2 5.2 2 2 2 5 5 5 0 Reovirus sigma C capsid protein Pox_A_type_inc PF04508.7 KND96989.1 - 5.7 6.9 14.2 6.5 6.8 0.5 6.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat tRNA_U5-meth_tr PF05958.6 KND96990.1 - 8e-11 41.2 0.0 1.3e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 KND96990.1 - 7.6e-06 25.5 0.0 2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 KND96990.1 - 0.018 14.8 0.2 0.097 12.4 0.0 2.2 2 0 0 2 2 2 0 TRAM domain DUF4348 PF14254.1 KND96990.1 - 0.029 13.4 0.3 1.9 7.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4348) Methyltransf_26 PF13659.1 KND96990.1 - 0.029 14.3 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 KND96990.1 - 0.04 13.6 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MA3 PF02847.12 KND96991.1 - 4.7e-21 74.5 0.4 1.9e-19 69.4 0.0 2.9 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.14 KND96991.1 - 2.6e-20 72.7 8.8 2.3e-19 69.6 4.8 2.5 2 1 0 2 2 2 1 MIF4G domain AAA PF00004.24 KND96992.1 - 1.5e-33 115.7 0.0 3.4e-33 114.6 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KND96992.1 - 7.1e-06 25.9 0.0 2.2e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KND96992.1 - 1.3e-05 25.3 0.8 0.0025 17.9 0.2 3.2 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KND96992.1 - 1.4e-05 25.8 0.1 6.4e-05 23.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KND96992.1 - 1.5e-05 24.8 0.0 3.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KND96992.1 - 1.6e-05 24.9 3.8 0.0042 17.0 0.0 3.1 3 1 1 4 4 3 2 AAA ATPase domain AAA_2 PF07724.9 KND96992.1 - 2.7e-05 24.1 0.0 8.4e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KND96992.1 - 2.7e-05 23.3 0.1 7e-05 21.9 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus ResIII PF04851.10 KND96992.1 - 0.00017 21.4 0.6 0.0036 17.1 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_5 PF07728.9 KND96992.1 - 0.00027 20.6 0.1 0.0017 18.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 KND96992.1 - 0.00032 21.0 0.9 0.0071 16.6 0.2 2.8 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 KND96992.1 - 0.00064 19.4 0.7 0.0098 15.5 0.1 2.4 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.16 KND96992.1 - 0.0019 17.4 0.1 0.0044 16.1 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.13 KND96992.1 - 0.0031 17.1 0.0 0.0066 16.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial dnaA protein IstB_IS21 PF01695.12 KND96992.1 - 0.0037 16.6 2.7 0.0061 15.9 0.0 2.6 4 0 0 4 4 3 1 IstB-like ATP binding protein RNA_helicase PF00910.17 KND96992.1 - 0.0047 17.0 0.1 0.013 15.6 0.0 1.8 2 0 0 2 2 1 1 RNA helicase NB-ARC PF00931.17 KND96992.1 - 0.0047 15.8 0.1 0.051 12.4 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Sigma54_activ_2 PF14532.1 KND96992.1 - 0.0048 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain Viral_helicase1 PF01443.13 KND96992.1 - 0.0052 16.3 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 KND96992.1 - 0.0062 15.9 0.5 0.062 12.7 0.1 2.3 1 1 1 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 KND96992.1 - 0.0063 15.4 0.0 0.0098 14.7 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 KND96992.1 - 0.0082 15.7 0.1 0.027 14.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 KND96992.1 - 0.0086 14.8 0.1 0.017 13.8 0.0 1.5 1 1 0 1 1 1 1 TIP49 C-terminus Zeta_toxin PF06414.7 KND96992.1 - 0.0096 15.0 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin DUF815 PF05673.8 KND96992.1 - 0.017 14.0 0.0 0.035 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 KND96992.1 - 0.019 14.7 0.0 0.052 13.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 KND96992.1 - 0.034 14.4 0.0 0.096 12.9 0.0 2.0 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 KND96992.1 - 0.044 13.7 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KND96992.1 - 0.059 12.7 1.2 1 8.7 0.9 2.8 1 1 0 1 1 1 0 AAA-like domain Sigma54_activat PF00158.21 KND96992.1 - 0.12 11.8 0.0 0.51 9.8 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_23 PF13476.1 KND96992.1 - 0.18 12.0 6.1 3.9 7.7 2.2 3.1 2 1 0 2 2 2 0 AAA domain LolB PF03550.9 KND96995.1 - 0.11 12.1 0.0 0.11 12.0 0.0 1.0 1 0 0 1 1 1 0 Outer membrane lipoprotein LolB RNA12 PF10443.4 KND96996.1 - 1e-144 482.2 5.2 1e-144 482.2 3.6 2.7 3 1 0 3 3 3 1 RNA12 protein RRM_1 PF00076.17 KND96996.1 - 2.2e-06 27.1 0.0 6.4e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND96996.1 - 0.0012 18.5 0.0 0.0029 17.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.4 KND96996.1 - 0.069 12.9 1.5 0.12 12.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2487) Arch_ATPase PF01637.13 KND96996.1 - 1.4 8.5 7.4 0.29 10.8 0.5 2.8 2 1 0 2 2 2 0 Archaeal ATPase Peptidase_C48 PF02902.14 KND96997.1 - 2.7e-35 121.9 0.2 5.1e-35 121.0 0.1 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GidB PF02527.10 KND96997.1 - 0.025 13.7 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G VTC PF09359.5 KND96999.1 - 8e-91 303.9 4.4 1.4e-90 303.1 3.1 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 KND96999.1 - 1.3e-15 57.9 16.6 8e-12 45.5 7.4 5.1 2 2 2 4 4 4 2 SPX domain DUF202 PF02656.10 KND96999.1 - 2.1e-09 37.4 3.0 4.7e-09 36.3 2.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) DUF4611 PF15387.1 KND96999.1 - 2 8.6 9.1 1.1 9.4 1.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) AF1Q PF15017.1 KND96999.1 - 2.6 8.0 9.3 0.15 11.9 1.8 2.3 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Clat_adaptor_s PF01217.15 KND97000.1 - 1.6e-13 50.6 0.2 2e-13 50.2 0.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CwfJ_C_1 PF04677.10 KND97000.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 AP-5_subunit_s1 PF15001.1 KND97000.1 - 0.34 10.8 4.5 3.6 7.4 0.1 2.1 1 1 1 2 2 2 0 AP-5 complex subunit sigma-1 Bromo_TP PF07524.8 KND97001.1 - 3.2e-05 23.5 0.0 6.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated Cyclin_N PF00134.18 KND97002.1 - 4e-10 39.3 0.1 7.4e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Spore_SspJ PF09575.5 KND97003.1 - 0.004 17.3 3.3 0.0043 17.2 2.3 1.1 1 0 0 1 1 1 1 Small spore protein J (Spore_SspJ) DUF1125 PF06563.6 KND97003.1 - 1.3 8.7 6.5 1.3 8.7 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1125) JAB PF01398.16 KND97004.1 - 4.9e-09 35.9 0.0 1.2e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Polysacc_deac_1 PF01522.16 KND97009.1 - 1.3e-13 50.6 0.0 1.8e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 KND97009.1 - 0.00015 20.7 0.0 0.00016 20.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF3436 PF11918.3 KND97009.1 - 0.13 12.4 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3436) FMN_red PF03358.10 KND97012.1 - 1.4e-08 34.4 0.0 2.5e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 KND97012.1 - 2.2e-06 27.7 0.0 4.5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 KND97012.1 - 0.00014 21.4 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold MDFI PF15316.1 KND97012.1 - 0.024 14.6 4.1 0.033 14.1 2.9 1.2 1 0 0 1 1 1 0 MyoD family inhibitor Flavodoxin_5 PF12724.2 KND97012.1 - 0.037 14.0 0.4 5.1 7.1 0.0 2.8 3 0 0 3 3 3 0 Flavodoxin domain Striatin PF08232.7 KND97012.1 - 0.16 12.2 4.1 0.26 11.6 2.9 1.2 1 0 0 1 1 1 0 Striatin family Flavodoxin_1 PF00258.20 KND97013.1 - 2.5e-09 37.2 0.0 4e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 KND97013.1 - 3e-09 36.5 0.0 3.8e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KND97013.1 - 0.0014 18.1 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Bacteriocin_IIc PF10439.4 KND97013.1 - 3.7 7.7 7.0 0.98 9.5 2.2 1.9 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Sugar_tr PF00083.19 KND97014.1 - 3.8e-32 111.4 35.8 5.4e-19 68.1 8.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KND97014.1 - 2.2e-23 82.5 38.0 6.5e-13 48.1 15.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Trypan_PARP PF05887.6 KND97016.1 - 0.0018 18.1 24.0 0.0018 18.1 16.6 1.7 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.8 KND97016.1 - 0.45 8.8 9.8 0.58 8.4 6.8 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Mitofilin PF09731.4 KND97016.1 - 0.8 8.2 6.2 0.82 8.2 4.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF3408 PF11888.3 KND97016.1 - 1.4 8.8 7.1 1.9 8.4 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) RR_TM4-6 PF06459.7 KND97016.1 - 1.8 8.3 9.3 2 8.2 6.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 YqfQ PF14181.1 KND97016.1 - 6.5 6.7 9.5 9.1 6.2 6.6 1.3 1 0 0 1 1 1 0 YqfQ-like protein ADH_zinc_N PF00107.21 KND97017.1 - 1.8e-25 88.9 0.1 1.9e-24 85.6 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KND97017.1 - 0.0018 19.1 0.2 0.0055 17.5 0.0 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase DUF2833 PF11090.3 KND97018.1 - 0.082 13.0 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) DNAP_B_exo_N PF08452.5 KND97018.1 - 1.7 8.0 4.7 0.61 9.4 0.5 2.2 2 0 0 2 2 2 0 DNA polymerase family B exonuclease domain, N-terminal LicD PF04991.8 KND97019.1 - 1.1e-34 120.3 0.4 4.1e-34 118.4 0.3 2.0 1 1 0 1 1 1 1 LicD family Cytochrome-c551 PF10643.4 KND97020.1 - 0.028 13.7 1.7 0.037 13.3 1.2 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 DUF3584 PF12128.3 KND97020.1 - 1 6.5 17.9 1.2 6.3 12.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Tn916-Xis PF09035.5 KND97021.1 - 0.13 12.4 0.1 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Excisionase from transposon Tn916 MFS_1 PF07690.11 KND97023.1 - 1.8e-46 158.4 46.9 3.3e-44 151.0 34.5 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KND97023.1 - 4.9e-16 58.0 28.0 6.2e-16 57.7 19.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KND97023.1 - 1.3e-08 33.9 20.3 1.3e-08 33.9 14.1 3.5 2 1 1 3 3 3 2 Sugar (and other) transporter Sugar_tr PF00083.19 KND97026.1 - 1e-129 433.0 19.2 1.2e-129 432.8 13.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND97026.1 - 1.2e-26 93.2 15.8 1.2e-26 93.2 10.9 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.8 KND97026.1 - 1.8 6.5 15.2 0.046 11.8 2.8 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector DUF4234 PF14018.1 KND97026.1 - 5.4 6.8 6.8 13 5.6 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) Sugar_tr PF00083.19 KND97028.1 - 1.4e-91 307.3 16.8 1.8e-91 306.9 11.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND97028.1 - 2.5e-16 59.3 23.2 2.3e-15 56.1 7.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily PalH PF08733.5 KND97028.1 - 0.0081 15.0 1.8 0.39 9.4 0.1 2.3 2 0 0 2 2 2 2 PalH/RIM21 Herpes_UL55 PF04537.7 KND97028.1 - 0.066 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL55 protein Fasciclin PF02469.17 KND97030.1 - 3.2e-11 43.3 3.7 0.00015 21.7 0.1 4.6 5 1 0 5 5 5 2 Fasciclin domain c-SKI_SMAD_bind PF08782.5 KND97030.1 - 0.095 12.8 0.1 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 c-SKI Smad4 binding domain RRM_1 PF00076.17 KND97031.1 - 2.2e-18 65.6 0.0 3.9e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND97031.1 - 2.2e-16 59.5 0.0 4.3e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND97031.1 - 6.9e-12 45.0 0.0 1.2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Adeno_Penton_B PF01686.12 KND97031.1 - 0.13 10.5 0.0 0.17 10.1 0.0 1.1 1 0 0 1 1 1 0 Adenovirus penton base protein FMN_bind_2 PF04299.7 KND97032.1 - 5.2e-58 195.2 0.3 6.3e-58 195.0 0.2 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Epimerase PF01370.16 KND97036.1 - 4.1e-21 75.5 0.0 5.2e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KND97036.1 - 2.3e-10 39.6 0.0 3.3e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KND97036.1 - 1.1e-07 31.9 0.3 2.6e-07 30.8 0.2 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KND97036.1 - 2.5e-07 29.8 0.0 5.2e-07 28.8 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KND97036.1 - 2.8e-07 30.6 0.0 5.1e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND97036.1 - 8.8e-05 22.2 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KND97036.1 - 0.00077 18.4 0.0 0.0015 17.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KND97036.1 - 0.0048 16.1 0.0 0.0098 15.1 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Sigma54_activ_2 PF14532.1 KND97036.1 - 0.089 12.8 0.0 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain CTV_P33 PF07184.6 KND97036.1 - 0.15 10.8 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Citrus tristeza virus P33 protein VIT1 PF01988.14 KND97039.1 - 7.4e-61 205.3 3.8 9.8e-61 204.9 2.7 1.2 1 0 0 1 1 1 1 VIT family Peptidase_M30 PF10460.4 KND97039.1 - 0.16 10.8 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase M30 PsbI PF02532.9 KND97039.1 - 0.57 9.8 3.4 1.2 8.8 2.4 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Fun_ATP-synt_8 PF05933.8 KND97039.1 - 1.5 8.8 4.6 2.9 8.0 3.2 1.5 1 0 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) Sugar_tr PF00083.19 KND97043.1 - 7e-119 397.3 26.9 8.8e-119 397.0 18.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND97043.1 - 3.1e-16 59.0 28.2 1.4e-12 46.9 1.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.2 KND97046.1 - 8.6e-43 144.5 2.9 9.5e-20 70.7 0.3 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KND97046.1 - 1.3e-32 111.5 3.2 1.5e-10 41.2 0.0 4.7 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 KND97046.1 - 1.9e-32 109.4 2.4 2.9e-06 26.8 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 KND97046.1 - 2.5e-32 110.1 7.1 7e-11 42.0 0.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND97046.1 - 1.6e-28 95.9 0.4 0.0012 18.8 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat MARVEL PF01284.18 KND97047.1 - 8.3e-28 97.0 22.2 9.7e-28 96.7 15.4 1.0 1 0 0 1 1 1 1 Membrane-associating domain CcmH PF03918.9 KND97047.1 - 0.053 12.5 0.1 0.49 9.3 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Cytochrom_B_N PF00033.14 KND97047.1 - 0.11 11.8 7.7 0.53 9.6 0.0 2.2 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB zinc_ribbon_5 PF13719.1 KND97047.1 - 0.14 11.7 0.3 0.24 10.9 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain DUF588 PF04535.7 KND97047.1 - 0.17 11.4 13.4 0.25 10.9 9.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF588) Ni_hydr_CYTB PF01292.15 KND97047.1 - 2.1 7.7 8.8 31 3.9 5.8 2.1 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 SKN1 PF03935.10 KND97050.1 - 4.1e-245 813.6 4.4 4.8e-245 813.4 3.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.10 KND97052.1 - 5.5e-239 793.4 3.4 6.4e-239 793.2 2.4 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) ketoacyl-synt PF00109.21 KND97053.1 - 1.9e-54 184.8 0.2 7.6e-54 182.8 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KND97053.1 - 1.9e-34 118.0 2.4 2.3e-34 117.8 0.6 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KND97053.1 - 1.6e-06 27.3 0.3 3.7e-05 22.8 0.0 2.6 3 0 0 3 3 3 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KND97053.1 - 0.018 14.4 1.2 0.27 10.6 0.1 2.9 3 0 0 3 3 3 0 Thiolase, C-terminal domain SpoVAD PF07451.6 KND97053.1 - 0.084 11.3 0.1 0.38 9.1 0.0 1.9 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) WW PF00397.21 KND97054.1 - 3e-05 23.7 0.4 6.1e-05 22.7 0.2 1.6 1 0 0 1 1 1 1 WW domain zf-C2H2 PF00096.21 KND97057.1 - 1.5e-11 43.8 8.7 2.9e-05 24.1 0.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND97057.1 - 4.2e-09 36.0 9.4 0.00045 20.3 2.8 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KND97057.1 - 9.7e-06 25.6 8.6 0.003 17.7 0.5 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 KND97057.1 - 0.00036 20.3 3.2 0.42 10.5 1.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KND97057.1 - 0.00041 20.4 0.9 0.13 12.4 0.5 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KND97057.1 - 0.00083 19.4 1.0 0.0089 16.1 0.7 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KND97057.1 - 0.0064 16.5 3.7 0.018 15.1 2.6 1.6 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding DUF2256 PF10013.4 KND97057.1 - 0.0072 16.0 0.5 2.8 7.7 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2256) DUF2321 PF10083.4 KND97057.1 - 0.072 12.5 0.0 0.083 12.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) KRTDAP PF15200.1 KND97057.1 - 0.086 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Keratinocyte differentiation-associated zf-met2 PF12907.2 KND97057.1 - 0.097 12.6 7.0 0.65 10.0 0.0 2.4 1 1 1 2 2 2 0 Zinc-binding zf-H2C2_5 PF13909.1 KND97057.1 - 0.91 9.8 4.2 2.8 8.3 2.9 1.9 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-BED PF02892.10 KND97057.1 - 2.8 7.7 7.8 3 7.6 2.6 2.5 1 1 1 2 2 2 0 BED zinc finger NCA2 PF08637.5 KND97058.1 - 1.2e-76 257.3 6.2 2e-76 256.7 4.3 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Mannosyl_trans3 PF11051.3 KND97060.1 - 1.7e-49 168.5 0.0 3.5e-49 167.5 0.0 1.5 2 0 0 2 2 2 1 Mannosyltransferase putative YusW PF14039.1 KND97060.1 - 0.0012 19.0 1.4 0.0028 17.9 0.9 1.5 1 0 0 1 1 1 1 YusW-like protein OKR_DC_1_N PF03709.10 KND97060.1 - 0.083 12.9 0.0 0.84 9.7 0.0 2.2 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain Asp PF00026.18 KND97062.1 - 4.9e-66 223.1 4.5 5.7e-66 222.9 3.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KND97062.1 - 2.7e-09 37.1 0.0 3.3e-08 33.6 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KND97062.1 - 0.00032 21.1 0.2 0.45 11.0 0.1 3.1 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KND97062.1 - 0.11 12.0 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal MFS_1 PF07690.11 KND97063.1 - 1.2e-13 50.5 39.4 1.2e-11 44.0 26.4 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF1011 PF06237.7 KND97065.1 - 0.011 15.6 2.8 2 8.3 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1011) Histone_HNS PF00816.16 KND97065.1 - 0.031 14.7 0.0 7.9 7.0 0.0 2.7 2 0 0 2 2 2 0 H-NS histone family DUF4611 PF15387.1 KND97065.1 - 0.04 14.0 7.9 0.42 10.7 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) YL1 PF05764.8 KND97065.1 - 0.25 10.9 6.2 3.1 7.3 0.0 2.1 2 0 0 2 2 2 0 YL1 nuclear protein SDA1 PF05285.7 KND97065.1 - 1.1 8.5 11.4 2.4 7.3 7.9 1.4 1 1 0 1 1 1 0 SDA1 Vfa1 PF08432.5 KND97065.1 - 1.1 9.2 9.1 0.11 12.4 0.2 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Macoilin PF09726.4 KND97065.1 - 3.5 5.7 19.2 4.9 5.3 13.3 1.3 1 0 0 1 1 1 0 Transmembrane protein Pox_RNA_Pol_19 PF05320.7 KND97065.1 - 5 6.8 9.6 9.1 5.9 0.7 2.2 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit PBP1_TM PF14812.1 KND97065.1 - 5.5 7.3 11.4 1.8 8.9 1.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.11 KND97066.1 - 1.4e-10 40.3 37.9 1.9e-05 23.5 15.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF688 PF05097.7 KND97066.1 - 0.14 11.0 0.4 0.2 10.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) VEFS-Box PF09733.4 KND97066.1 - 0.17 11.5 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 VEFS-Box of polycomb protein DUF1935 PF09149.5 KND97069.1 - 0.0068 16.3 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) MFS_1 PF07690.11 KND97071.1 - 1.5e-10 40.3 26.0 2.6e-09 36.2 6.7 2.5 1 1 0 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 KND97071.1 - 0.23 9.8 14.3 0.054 11.9 6.9 2.0 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like DUF2721 PF11026.3 KND97071.1 - 0.34 10.5 0.0 0.34 10.5 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) Zn_clus PF00172.13 KND97072.1 - 2.8e-08 33.5 13.9 5.7e-08 32.5 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KND97073.1 - 5.2e-49 167.0 0.0 7.8e-49 166.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FleQ PF06490.6 KND97074.1 - 0.093 12.8 0.1 0.099 12.7 0.0 1.1 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ Sugar_tr PF00083.19 KND97075.1 - 1.8e-84 283.9 29.8 2.1e-84 283.7 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND97075.1 - 3.8e-25 88.3 39.7 1.5e-19 69.9 21.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KND97075.1 - 0.0067 14.8 32.8 0.0094 14.3 2.0 3.3 2 1 0 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.19 KND97076.1 - 3.5e-85 286.2 26.3 4e-85 286.0 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND97076.1 - 3.5e-26 91.7 40.7 8.8e-21 74.0 21.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-RNPHF PF08080.7 KND97076.1 - 0.13 11.8 2.5 0.77 9.3 0.1 2.4 2 0 0 2 2 2 0 RNPHF zinc finger Sugar_tr PF00083.19 KND97078.1 - 3.4e-84 283.0 27.1 3.9e-84 282.8 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND97078.1 - 1.4e-24 86.4 56.8 1.8e-19 69.6 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cellulase PF00150.13 KND97079.1 - 5.4e-10 38.9 0.7 7.9e-06 25.2 0.2 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Imm32 PF15579.1 KND97080.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 32 DUF3496 PF12001.3 KND97081.1 - 0.013 15.7 0.4 0.016 15.4 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) RVT_1 PF00078.22 KND97084.1 - 4.2e-05 22.9 0.1 7.2e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 KND97084.1 - 0.00033 20.6 0.0 0.00067 19.6 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4168 PF13767.1 KND97084.1 - 0.074 13.6 0.3 0.26 11.9 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) Ycf1 PF05758.7 KND97085.1 - 0.13 9.9 0.6 0.15 9.7 0.4 1.0 1 0 0 1 1 1 0 Ycf1 HTH_Tnp_4 PF13613.1 KND97086.1 - 0.27 10.7 1.7 0.44 10.1 1.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Sugar_tr PF00083.19 KND97087.1 - 1.6e-89 300.5 28.1 1.8e-89 300.3 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND97087.1 - 1.9e-30 105.8 18.5 1.9e-30 105.8 12.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND97089.1 - 2.1e-88 296.8 26.7 2.4e-88 296.6 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND97089.1 - 4e-32 111.3 20.6 4e-32 111.3 14.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KND97089.1 - 7.1e-06 24.6 8.7 7.1e-06 24.6 6.0 3.0 2 2 1 3 3 3 2 MFS/sugar transport protein Glyco_hydro_3 PF00933.16 KND97090.1 - 3.1e-71 239.7 0.0 4.6e-71 239.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KND97090.1 - 1.1e-56 191.8 0.0 1.6e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KND97090.1 - 1.5e-15 56.8 0.1 2.9e-15 55.9 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KND97090.1 - 1.4e-06 28.0 0.0 2.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 PA14 domain MFS_1 PF07690.11 KND97092.1 - 2.3e-10 39.7 43.3 6.9e-06 25.0 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_72 PF03198.9 KND97093.1 - 1.6e-62 211.2 0.2 2.1e-62 210.9 0.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase F-box-like PF12937.2 KND97094.1 - 3.6e-10 39.4 0.1 1.1e-09 37.9 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KND97094.1 - 1.5e-05 24.4 0.6 5.4e-05 22.7 0.1 2.3 2 0 0 2 2 2 1 F-box domain F-box-like_2 PF13013.1 KND97094.1 - 0.037 13.7 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 F-box-like domain LUC7 PF03194.10 KND97095.1 - 9.8e-65 218.5 1.4 1.2e-64 218.2 1.0 1.0 1 0 0 1 1 1 1 LUC7 N_terminus V-SNARE PF05008.10 KND97095.1 - 0.011 15.8 0.2 0.027 14.6 0.2 1.7 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Peptidase_M48 PF01435.13 KND97096.1 - 4.2e-45 154.0 0.0 5.5e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 DUF2201_N PF13203.1 KND97096.1 - 0.0087 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Putative metallopeptidase domain DUF955 PF06114.8 KND97096.1 - 0.14 11.8 0.2 0.35 10.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF955) DUF2838 PF10998.3 KND97097.1 - 1.5 8.7 5.1 2 8.3 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) FAM165 PF14981.1 KND97098.1 - 0.024 14.1 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 FAM165 family DUF1145 PF06611.7 KND97098.1 - 0.033 13.8 1.4 0.4 10.3 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1145) SUR7 PF06687.7 KND97098.1 - 0.057 12.9 1.0 0.068 12.7 0.7 1.0 1 0 0 1 1 1 0 SUR7/PalI family FixQ PF05545.6 KND97098.1 - 0.16 11.6 0.2 0.16 11.6 0.2 1.8 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ zf-DHHC PF01529.15 KND97098.1 - 0.4 10.0 3.8 0.51 9.7 2.6 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase DEAD PF00270.24 KND97100.1 - 2.7e-43 147.4 0.1 2.7e-43 147.4 0.1 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND97100.1 - 1.2e-23 82.7 0.0 2.9e-23 81.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KND97100.1 - 0.0001 20.8 2.4 0.00051 18.5 0.0 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF1253) SYS1 PF09801.4 KND97101.1 - 1.8e-50 170.6 17.0 2.1e-50 170.4 11.8 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network MatC_N PF07158.6 KND97101.1 - 0.66 9.7 5.6 0.41 10.4 2.3 1.7 1 1 1 2 2 2 0 Dicarboxylate carrier protein MatC N-terminus SCP2 PF02036.12 KND97103.1 - 6.2e-17 61.7 0.2 7.7e-17 61.4 0.2 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 KND97103.1 - 0.0011 18.9 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal p450 PF00067.17 KND97104.1 - 9.1e-64 215.6 0.1 1.2e-63 215.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KND97105.1 - 3.1e-45 154.5 0.0 1.4e-44 152.3 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Vac7 PF12751.2 KND97106.1 - 1.1e-23 83.6 18.5 1.1e-15 57.4 0.2 3.2 2 1 1 4 4 4 2 Vacuolar segregation subunit 7 6PF2K PF01591.13 KND97107.1 - 6.3e-75 251.0 0.0 1.5e-74 249.8 0.0 1.7 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KND97107.1 - 6.1e-24 84.8 0.1 1.9e-23 83.3 0.0 2.0 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 KND97107.1 - 0.00029 21.6 0.1 0.0098 16.7 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 KND97107.1 - 0.00044 20.1 0.1 0.0075 16.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KND97107.1 - 0.085 12.8 0.0 0.42 10.5 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase Methyltransf_16 PF10294.4 KND97112.1 - 1.1e-06 28.1 0.1 0.00026 20.4 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_23 PF13489.1 KND97112.1 - 0.083 12.6 0.0 1.3 8.7 0.0 2.7 1 1 1 2 2 2 0 Methyltransferase domain Xpo1 PF08389.7 KND97113.1 - 3.5e-05 23.7 10.8 0.00012 22.0 0.3 5.3 6 0 0 6 6 6 1 Exportin 1-like protein IBN_N PF03810.14 KND97113.1 - 0.001 18.9 1.0 0.25 11.2 0.0 4.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain SynMuv_product PF06047.6 KND97113.1 - 0.057 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Ras-induced vulval development antagonist Brix PF04427.13 KND97115.1 - 1.5e-41 142.1 1.2 2.2e-41 141.6 0.8 1.2 1 0 0 1 1 1 1 Brix domain BSD PF03909.12 KND97116.1 - 4.3e-25 87.2 0.3 2.7e-15 55.8 0.0 3.1 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 KND97116.1 - 1.9e-17 62.6 0.1 4.5e-17 61.4 0.1 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain MaoC_dehydratas PF01575.14 KND97117.1 - 7.4e-06 25.3 0.0 4.7e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KND97117.1 - 3.2e-05 23.7 0.0 0.012 15.3 0.0 2.4 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Metallothio_11 PF02066.10 KND97117.1 - 0.32 10.9 1.2 0.58 10.0 0.1 1.9 2 0 0 2 2 2 0 Metallothionein family 11 Ribonuclease_T2 PF00445.13 KND97118.1 - 3.2e-39 134.5 0.9 3.8e-39 134.2 0.6 1.0 1 0 0 1 1 1 1 Ribonuclease T2 family Sod_Cu PF00080.15 KND97119.1 - 3.8e-36 124.3 1.9 4.2e-36 124.2 1.3 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF1772 PF08592.6 KND97120.1 - 0.013 15.2 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Inhibitor_I9 PF05922.11 KND97121.1 - 2.7e-11 43.8 0.0 3.4e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 Glyco_hydro_38 PF01074.17 KND97122.1 - 1.4e-83 280.3 0.7 3.9e-83 278.8 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KND97122.1 - 4.1e-65 220.3 4.8 6.2e-65 219.7 3.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KND97122.1 - 5.1e-26 90.6 0.0 1.7e-25 88.9 0.0 2.0 1 0 0 1 1 1 1 Alpha mannosidase, middle domain SBDS_C PF09377.5 KND97123.1 - 1.9e-35 121.2 0.4 3.5e-35 120.4 0.3 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 KND97123.1 - 2.6e-32 110.4 0.5 4.4e-32 109.7 0.4 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein XkdN PF08890.6 KND97123.1 - 0.022 14.4 0.1 0.059 13.1 0.1 1.8 1 1 0 1 1 1 0 Phage XkdN-like protein DnaJ PF00226.26 KND97124.1 - 2.4e-17 62.4 0.1 2.4e-17 62.4 0.1 2.6 2 0 0 2 2 2 1 DnaJ domain IPP-2 PF04979.9 KND97125.1 - 6.7e-12 45.7 13.7 6.7e-12 45.7 9.5 1.9 1 1 1 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Arf PF00025.16 KND97126.1 - 2e-75 251.8 0.2 2.3e-75 251.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KND97126.1 - 4.6e-11 42.2 0.0 6.1e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KND97126.1 - 8.7e-11 41.3 0.0 1.1e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KND97126.1 - 1.3e-10 40.8 0.0 1.5e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KND97126.1 - 2.2e-10 39.8 0.9 1.4e-06 27.2 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KND97126.1 - 2e-09 37.9 0.0 2.7e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 KND97126.1 - 7.7e-05 21.5 0.6 0.0067 15.2 0.1 2.8 2 1 0 2 2 2 1 ArgK protein MMR_HSR1 PF01926.18 KND97126.1 - 0.00014 21.8 0.1 0.00022 21.1 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KND97126.1 - 0.00028 20.3 0.1 0.0075 15.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KND97126.1 - 0.0027 17.9 0.1 0.007 16.6 0.1 1.7 1 1 0 1 1 1 1 ABC transporter cobW PF02492.14 KND97126.1 - 0.13 11.7 0.8 3.9 6.8 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 KND97126.1 - 0.15 11.4 0.3 0.5 9.7 0.1 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NACHT PF05729.7 KND97126.1 - 0.16 11.5 0.4 5.6 6.5 0.1 2.2 2 0 0 2 2 2 0 NACHT domain PDH PF02153.12 KND97127.1 - 2.8e-14 52.6 0.0 4.3e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 KND97127.1 - 2.6e-08 33.8 0.1 5.3e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KND97127.1 - 8.3e-07 29.3 0.1 1.9e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 KND97127.1 - 1.4e-05 24.3 0.1 2.7e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KND97127.1 - 7.3e-05 22.4 0.2 0.00019 21.1 0.1 1.7 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KND97127.1 - 0.0011 18.3 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.7 KND97127.1 - 0.0026 17.1 0.2 0.0049 16.2 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 KND97127.1 - 0.006 16.5 0.0 0.019 14.9 0.0 1.9 1 0 0 1 1 1 1 TrkA-N domain Rossmann-like PF10727.4 KND97127.1 - 0.021 14.5 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain UDPG_MGDP_dh_N PF03721.9 KND97127.1 - 0.034 13.5 0.0 0.071 12.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GHMP_kinases_N PF00288.21 KND97129.1 - 2.2e-12 46.8 0.1 6.3e-12 45.3 0.1 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KND97129.1 - 2.9e-06 27.3 0.0 1.4e-05 25.1 0.0 2.2 2 1 0 2 2 2 1 GHMP kinases C terminal HAMP PF00672.20 KND97129.1 - 0.014 15.5 0.2 0.18 12.0 0.0 2.3 2 0 0 2 2 2 0 HAMP domain Kelch_5 PF13854.1 KND97131.1 - 0.0013 18.6 2.2 12 5.9 0.1 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 KND97131.1 - 0.0024 17.5 0.1 0.0024 17.5 0.0 3.8 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_1 PF01344.20 KND97131.1 - 0.0068 15.9 0.4 0.03 13.8 0.0 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 KND97131.1 - 0.0078 16.3 2.5 0.73 10.0 0.0 3.8 3 1 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.10 KND97131.1 - 0.047 13.4 4.0 0.26 11.1 0.0 3.8 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.1 KND97131.1 - 0.049 13.8 0.4 25 5.2 0.0 3.9 3 0 0 3 3 3 0 Kelch motif zf-Tim10_DDP PF02953.10 KND97132.1 - 3e-24 84.0 2.1 3.5e-24 83.8 1.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 KND97132.1 - 0.013 14.9 2.1 0.017 14.5 1.5 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Macin PF14865.1 KND97132.1 - 0.078 13.0 0.4 0.13 12.3 0.3 1.4 1 0 0 1 1 1 0 Macin Tom5 PF10642.4 KND97132.1 - 0.089 12.4 1.5 0.096 12.3 0.2 1.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase DUF4444 PF14563.1 KND97132.1 - 0.11 11.9 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4444) Defensin_2 PF01097.13 KND97132.1 - 0.3 10.8 2.7 1.4 8.7 0.3 2.1 1 1 1 2 2 2 0 Arthropod defensin Cyto_heme_lyase PF01265.12 KND97133.1 - 1.3e-83 280.5 0.6 1.6e-83 280.2 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Sigma_reg_C PF13791.1 KND97133.1 - 0.14 12.1 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Sigma factor regulator C-terminal SURF4 PF02077.10 KND97135.1 - 8.7e-91 303.9 12.9 1e-90 303.7 9.0 1.0 1 0 0 1 1 1 1 SURF4 family VirB8 PF04335.8 KND97135.1 - 0.17 11.4 0.2 0.34 10.4 0.2 1.4 1 0 0 1 1 1 0 VirB8 protein DUF2628 PF10947.3 KND97135.1 - 9.7 6.0 16.2 9.1 6.1 3.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) RNase_PH PF01138.16 KND97136.1 - 4.6e-33 114.3 0.1 6.5e-33 113.8 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KND97136.1 - 6.9e-07 29.1 0.4 1.3e-06 28.2 0.3 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Mannosyl_trans PF05007.8 KND97137.1 - 3.9e-73 246.2 21.5 5.7e-73 245.7 14.9 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 KND97137.1 - 8.2e-15 54.5 9.4 8.2e-15 54.5 6.5 2.1 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 KND97137.1 - 0.0011 18.5 5.2 0.0011 18.5 3.6 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2029) HsdM_N PF12161.3 KND97138.1 - 0.1 13.0 0.1 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 HsdM N-terminal domain Mito_carr PF00153.22 KND97139.1 - 2.1e-51 171.6 0.9 1.6e-20 72.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF383 PF04063.9 KND97140.1 - 3.1e-72 242.1 0.2 3.1e-72 242.1 0.2 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 KND97140.1 - 1.3e-23 82.2 0.5 4.7e-23 80.4 0.4 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Type_III_YscX PF09474.5 KND97140.1 - 0.069 13.1 0.9 0.25 11.3 0.0 2.2 2 1 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) Peptidase_M20 PF01546.23 KND97141.1 - 3.7e-22 78.7 0.0 5.8e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KND97141.1 - 1e-12 47.7 0.1 3.1e-12 46.2 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KND97141.1 - 2.1e-05 24.3 0.0 4.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 DLH PF01738.13 KND97142.1 - 7.7e-32 110.3 0.0 8.6e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KND97142.1 - 6e-05 22.8 0.0 8.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family ABC1 PF03109.11 KND97143.1 - 5.1e-25 87.7 0.1 2.3e-15 56.5 0.0 2.6 2 0 0 2 2 2 2 ABC1 family RIO1 PF01163.17 KND97143.1 - 0.00051 19.4 0.2 0.0019 17.5 0.0 1.9 2 0 0 2 2 2 1 RIO1 family DUF676 PF05057.9 KND97144.1 - 4.6e-42 143.7 0.0 7e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 KND97144.1 - 0.00036 20.1 0.0 0.00066 19.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KND97144.1 - 0.0089 15.7 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KND97144.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 KND97144.1 - 0.037 13.9 0.0 0.15 11.9 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.13 KND97144.1 - 0.17 11.1 0.0 0.44 9.8 0.0 1.7 1 0 0 1 1 1 0 Dienelactone hydrolase family Proteasome PF00227.21 KND97145.1 - 5.6e-38 130.1 0.2 3.6e-37 127.5 0.1 1.8 1 1 0 1 1 1 1 Proteasome subunit ER_lumen_recept PF00810.13 KND97146.1 - 9e-55 185.2 12.2 9e-55 185.2 8.4 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KND97146.1 - 0.00026 20.4 11.3 0.24 10.9 0.3 4.4 3 1 1 4 4 4 3 PQ loop repeat DUF1516 PF07457.6 KND97146.1 - 0.031 14.3 3.9 0.07 13.2 2.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1516) Thioredoxin PF00085.15 KND97147.1 - 1.8e-15 56.4 0.0 7.8e-13 48.0 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.1 KND97147.1 - 1.9e-07 31.0 4.3 0.01 15.9 0.1 4.3 2 2 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KND97147.1 - 2.3e-07 30.9 0.4 0.00032 20.8 0.2 3.2 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_6 PF13848.1 KND97147.1 - 1.1e-06 28.5 14.4 2e-05 24.4 4.1 2.5 1 1 1 2 2 2 2 Thioredoxin-like domain TraF PF13728.1 KND97147.1 - 0.00038 20.0 0.1 0.0063 16.0 0.1 2.5 2 1 0 2 2 2 1 F plasmid transfer operon protein HyaE PF07449.6 KND97147.1 - 0.0008 19.2 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.16 KND97147.1 - 0.024 14.3 0.3 0.091 12.4 0.1 2.1 1 1 1 2 2 2 0 AhpC/TSA family Thioredoxin_7 PF13899.1 KND97147.1 - 0.08 12.9 0.0 4.6 7.3 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin-like Flocculin_t3 PF13928.1 KND97148.1 - 5.6e-23 80.8 71.2 7.8e-13 48.3 13.6 6.1 6 1 0 6 6 6 3 Flocculin type 3 repeat DUF3347 PF11827.3 KND97148.1 - 0.08 12.9 0.0 4.4 7.2 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3347) CPSF_A PF03178.10 KND97149.1 - 1.7e-85 286.9 0.0 1.3e-83 280.7 0.0 2.4 2 0 0 2 2 2 2 CPSF A subunit region MMS1_N PF10433.4 KND97149.1 - 5.8e-10 37.9 4.6 9.5e-07 27.3 0.1 3.2 3 0 0 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term PIG-F PF06699.6 KND97151.1 - 2e-51 174.6 13.1 2.7e-51 174.2 9.1 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F 7TM_GPCR_Srz PF10325.4 KND97151.1 - 0.0079 15.3 3.9 0.01 14.9 2.7 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srz GNVR PF13807.1 KND97151.1 - 0.021 14.5 1.6 2.8 7.7 0.2 3.2 3 0 0 3 3 3 0 G-rich domain on putative tyrosine kinase PRA1 PF03208.14 KND97151.1 - 0.57 9.4 14.7 1.4 8.2 8.9 2.1 2 0 0 2 2 2 0 PRA1 family protein tRNA-synt_1b PF00579.20 KND97153.1 - 5.2e-70 235.8 0.0 6.3e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) zf-UBR PF02207.15 KND97154.1 - 4.3e-16 58.3 13.0 4.3e-16 58.3 9.0 2.4 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 KND97154.1 - 7.5e-08 32.0 0.0 1.6e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-UBR PF02207.15 KND97155.1 - 2.2e-17 62.5 8.6 2.2e-17 62.5 6.0 2.3 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.1 KND97155.1 - 0.0011 18.7 1.3 0.0011 18.7 0.9 3.5 4 0 0 4 4 4 1 Ring finger domain ClpS PF02617.12 KND97155.1 - 0.0021 17.7 0.0 0.0075 15.9 0.0 1.9 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-C3HC4_2 PF13923.1 KND97155.1 - 3 7.9 12.7 0.059 13.3 0.3 3.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SH3_9 PF14604.1 KND97156.1 - 1.2e-26 92.0 4.2 4.6e-13 48.5 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KND97156.1 - 1.1e-23 82.3 7.4 2.1e-11 43.0 0.9 2.5 2 0 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.15 KND97156.1 - 5.6e-19 68.2 0.8 9.6e-19 67.5 0.0 1.9 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.12 KND97156.1 - 6.1e-15 54.4 0.2 3.4e-06 26.4 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain Citrate_ly_lig PF08218.6 KND97158.1 - 0.067 12.6 0.1 0.067 12.6 0.0 1.0 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain DUF1877 PF08974.5 KND97158.1 - 0.087 12.4 0.1 0.096 12.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) SPRY PF00622.23 KND97159.1 - 6.4e-15 55.3 0.0 1.1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Glyco_hydro_17 PF00332.13 KND97160.1 - 2.6e-46 158.1 1.5 2.9e-46 157.9 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 VWA_2 PF13519.1 KND97160.1 - 0.092 12.8 0.0 0.14 12.2 0.0 1.4 1 1 0 1 1 1 0 von Willebrand factor type A domain Methyltrn_RNA_3 PF02598.12 KND97162.1 - 1.1e-70 238.2 1.0 1.3e-70 238.0 0.7 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Reo_sigmaC PF04582.7 KND97163.1 - 0.0077 15.4 16.2 0.068 12.3 2.3 3.4 3 1 1 4 4 4 3 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 KND97163.1 - 0.047 13.5 19.1 3.7 7.3 0.1 4.9 3 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 KND97163.1 - 0.088 12.3 53.7 0.11 12.0 7.6 4.8 2 1 3 5 5 5 0 IncA protein DUF4041 PF13250.1 KND97163.1 - 0.28 10.7 9.4 1.1 8.8 0.4 4.5 4 1 0 4 4 4 0 Domain of unknown function (DUF4041) DUF3584 PF12128.3 KND97163.1 - 0.8 6.9 46.7 0.26 8.5 26.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) NUDIX PF00293.23 KND97164.1 - 1.7e-24 85.9 0.0 2.5e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Radical_SAM PF04055.16 KND97165.1 - 4.6e-10 39.9 0.0 7.6e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Oxidored_nitro PF00148.14 KND97165.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Hist_deacetyl PF00850.14 KND97167.1 - 2.6e-64 217.4 0.0 3.8e-64 216.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain RhoGAP PF00620.22 KND97168.1 - 5.6e-28 97.4 1.0 1.4e-27 96.1 0.0 2.2 3 0 0 3 3 3 1 RhoGAP domain PH PF00169.24 KND97168.1 - 2.8e-06 27.4 0.0 7.9e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 PH domain PX PF00787.19 KND97168.1 - 0.00017 21.3 0.2 0.0014 18.4 0.0 2.5 3 0 0 3 3 3 1 PX domain PH_11 PF15413.1 KND97168.1 - 0.0046 17.1 0.0 0.028 14.6 0.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.1 KND97168.1 - 0.045 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain TFIIA PF03153.8 KND97169.1 - 4.6e-57 194.6 18.1 5e-33 115.5 8.7 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Ependymin PF00811.13 KND97170.1 - 1.1 8.9 5.9 0.82 9.3 0.7 2.3 1 1 1 2 2 2 0 Ependymin Rer1 PF03248.8 KND97171.1 - 2.1e-77 258.7 3.3 2.4e-77 258.5 2.3 1.0 1 0 0 1 1 1 1 Rer1 family ANTH PF07651.11 KND97172.1 - 3.8e-77 258.7 0.7 3.8e-77 258.7 0.5 3.2 4 0 0 4 4 4 1 ANTH domain I_LWEQ PF01608.12 KND97172.1 - 7.1e-64 214.3 8.1 7.1e-64 214.3 5.6 5.4 3 2 3 7 7 7 1 I/LWEQ domain DUF3600 PF12207.3 KND97172.1 - 0.0055 16.2 8.2 0.014 14.8 5.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3600) Mito_carr PF00153.22 KND97173.1 - 4.5e-57 189.7 1.2 3.3e-18 65.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein UCR_14kD PF02271.11 KND97175.1 - 4.6e-31 106.6 0.5 5.3e-31 106.5 0.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit ATP_transf PF09830.4 KND97176.1 - 2.6e-18 65.5 0.0 4.7e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 KND97176.1 - 0.00088 19.7 0.0 0.0022 18.4 0.0 1.6 2 0 0 2 2 2 1 HIT domain Spb1_C PF07780.7 KND97178.1 - 1.6e-74 250.0 18.6 1.6e-74 250.0 12.9 3.8 3 1 1 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.14 KND97178.1 - 1.3e-51 175.1 1.7 2.4e-51 174.3 0.0 2.3 3 0 0 3 3 3 1 FtsJ-like methyltransferase DUF3381 PF11861.3 KND97178.1 - 2e-45 154.1 15.6 2e-45 154.1 10.8 3.8 3 2 1 4 4 4 1 Domain of unknown function (DUF3381) Pep3_Vps18 PF05131.9 KND97179.1 - 1.5e-13 50.3 0.2 1.2e-12 47.5 0.0 2.4 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Vps39_2 PF10367.4 KND97179.1 - 5.7e-07 29.6 2.5 5.7e-07 29.6 1.7 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Prok-RING_1 PF14446.1 KND97179.1 - 0.00015 21.3 0.7 0.00031 20.4 0.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-RING_2 PF13639.1 KND97179.1 - 0.00087 19.0 5.5 0.0029 17.4 3.9 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KND97179.1 - 0.0026 17.7 1.3 0.0026 17.7 0.9 2.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) DUF3677 PF12432.3 KND97179.1 - 0.0047 17.3 0.4 0.015 15.7 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3677) zf-RING_5 PF14634.1 KND97179.1 - 0.017 14.8 1.9 0.049 13.3 1.3 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Somatostatin PF03002.10 KND97179.1 - 0.1 12.2 0.7 0.21 11.2 0.5 1.4 1 0 0 1 1 1 0 Somatostatin/Cortistatin family PHD PF00628.24 KND97179.1 - 0.12 12.0 1.0 0.27 10.9 0.7 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 KND97179.1 - 0.27 11.2 1.2 0.75 9.8 0.9 1.8 1 0 0 1 1 1 0 RING-like domain zf-C3HC4 PF00097.20 KND97179.1 - 0.27 10.9 1.2 0.71 9.5 0.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KND97179.1 - 0.65 10.1 6.0 0.1 12.7 1.0 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger CH PF00307.26 KND97180.1 - 3.8e-71 236.0 0.0 6.1e-20 71.2 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KND97180.1 - 3.2e-10 39.5 0.0 0.29 10.7 0.0 4.5 4 0 0 4 4 4 3 CAMSAP CH domain EF-hand_1 PF00036.27 KND97180.1 - 0.00046 19.2 1.0 0.02 14.1 0.0 3.3 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 KND97180.1 - 0.17 12.0 4.6 0.25 11.4 0.5 3.0 3 0 0 3 3 3 0 EF-hand domain pair Complex1_LYR PF05347.10 KND97181.1 - 2e-07 30.7 3.0 3.3e-07 30.0 2.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KND97181.1 - 6.1e-07 29.5 3.1 8.3e-07 29.1 2.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DUF4080 PF13311.1 KND97181.1 - 0.098 12.6 0.1 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4080) CDO_I PF05995.7 KND97181.1 - 0.15 11.2 0.2 0.25 10.5 0.1 1.4 1 1 1 2 2 2 0 Cysteine dioxygenase type I Ribosomal_L10 PF00466.15 KND97182.1 - 3.6e-12 46.0 0.1 5.2e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 CENP-C_C PF11699.3 KND97183.1 - 5.2e-16 58.4 0.0 1.1e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 KND97183.1 - 1.3e-10 42.0 13.1 1.3e-10 42.0 9.1 2.9 1 1 2 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 KND97183.1 - 0.00017 21.0 0.0 0.00038 19.8 0.0 1.6 1 0 0 1 1 1 1 Cupin domain DNA_pol3_delta PF06144.8 KND97183.1 - 0.021 14.3 0.3 0.04 13.4 0.2 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit CRT10 PF08728.5 KND97184.1 - 4.4e-83 279.5 1.2 1.3e-52 178.8 0.3 2.3 1 1 1 2 2 2 2 CRT10 Helicase_C_2 PF13307.1 KND97185.1 - 0.025 14.5 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain GAF_2 PF13185.1 KND97186.1 - 6.8e-11 42.8 0.0 8.3e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 KND97186.1 - 9.5e-07 29.0 0.0 1.1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 KND97186.1 - 2.2e-06 27.8 0.0 2.9e-06 27.4 0.0 1.3 1 1 0 1 1 1 1 GAF domain Lactate_perm PF02652.9 KND97186.1 - 0.12 10.8 0.1 0.14 10.6 0.1 1.1 1 0 0 1 1 1 0 L-lactate permease KH_1 PF00013.24 KND97187.1 - 8.9e-38 127.7 0.9 2.2e-14 52.8 0.5 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KND97187.1 - 5.4e-23 80.1 12.6 4.6e-08 32.5 2.0 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KND97187.1 - 2e-08 33.6 5.3 0.012 15.1 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KND97187.1 - 2.2e-07 30.4 6.6 0.0061 16.1 0.0 3.8 4 0 0 4 4 4 3 KH domain KH_5 PF13184.1 KND97187.1 - 1.1e-06 28.2 0.6 0.83 9.4 0.0 3.4 3 0 0 3 3 3 3 NusA-like KH domain PH_5 PF15405.1 KND97193.1 - 0.043 13.7 0.3 0.053 13.4 0.2 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain AgrB PF04647.10 KND97193.1 - 0.12 11.4 0.3 0.13 11.3 0.2 1.1 1 0 0 1 1 1 0 Accessory gene regulator B SRP54 PF00448.17 KND97194.1 - 1.7e-77 259.3 1.1 1.7e-77 259.3 0.8 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 KND97194.1 - 8.1e-24 83.8 6.7 8.1e-24 83.8 4.6 4.3 3 1 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.14 KND97194.1 - 3.6e-15 55.8 3.9 9.6e-15 54.4 2.7 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 KND97194.1 - 4.8e-07 29.4 2.5 7.6e-05 22.2 0.4 3.1 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KND97194.1 - 3e-05 23.7 0.4 0.00017 21.2 0.1 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KND97194.1 - 4.3e-05 23.4 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 KND97194.1 - 9e-05 21.9 0.6 0.00059 19.3 0.4 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KND97194.1 - 0.0011 18.8 0.0 0.14 12.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KND97194.1 - 0.0037 18.0 0.1 0.0084 16.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain ArgK PF03308.11 KND97194.1 - 0.008 14.9 1.9 0.016 14.0 0.0 2.4 3 0 0 3 3 3 1 ArgK protein APS_kinase PF01583.15 KND97194.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase SRPRB PF09439.5 KND97194.1 - 0.034 13.3 4.9 3.6 6.7 0.0 3.8 4 0 0 4 4 4 0 Signal recognition particle receptor beta subunit MipZ PF09140.6 KND97194.1 - 0.045 12.8 0.2 7.3 5.5 0.0 2.6 2 0 0 2 2 2 0 ATPase MipZ AAA_18 PF13238.1 KND97194.1 - 0.045 14.0 0.5 0.35 11.1 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.1 KND97194.1 - 0.08 13.0 1.2 0.34 11.0 0.1 2.6 2 1 0 2 2 2 0 AAA domain Glyco_trans_4_2 PF13477.1 KND97194.1 - 0.084 12.7 0.0 0.29 10.9 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase 4-like Zeta_toxin PF06414.7 KND97194.1 - 0.11 11.5 0.8 0.44 9.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.12 KND97194.1 - 0.22 11.0 0.1 0.22 11.0 0.1 2.9 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein LRR_6 PF13516.1 KND97195.1 - 3.6e-05 23.3 5.0 0.88 9.8 0.1 5.1 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.2 KND97195.1 - 0.00025 20.5 10.5 0.58 9.8 0.4 5.2 4 1 0 5 5 5 3 Leucine Rich repeats (2 copies) DUF3145 PF11343.3 KND97195.1 - 0.15 11.4 0.1 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) LRR_1 PF00560.28 KND97195.1 - 0.28 11.3 10.7 26 5.3 0.0 6.2 5 2 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 KND97195.1 - 3.1 8.3 7.8 1.7e+02 3.1 0.0 5.6 5 0 0 5 5 5 0 Leucine rich repeat Elf1 PF05129.8 KND97196.1 - 1.1e-29 101.8 2.4 1.4e-29 101.5 1.7 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like EST1_DNA_bind PF10373.4 KND97196.1 - 0.059 12.5 0.0 0.07 12.3 0.0 1.1 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Zn-ribbon_8 PF09723.5 KND97196.1 - 0.24 11.3 2.2 0.88 9.5 1.5 1.9 1 1 0 1 1 1 0 Zinc ribbon domain zf-C2H2_2 PF12756.2 KND97196.1 - 0.33 11.0 3.3 1.5 8.9 0.5 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 KND97196.1 - 0.55 10.2 0.2 0.55 10.2 0.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-FCS PF06467.9 KND97196.1 - 0.61 9.7 5.0 7.8 6.2 3.5 2.1 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif RabGAP-TBC PF00566.13 KND97197.1 - 6.2e-16 58.5 9.5 7.6e-16 58.2 6.2 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Bac_surface_Ag PF01103.18 KND97198.1 - 8.8e-12 45.1 11.7 1.5e-11 44.3 8.1 1.4 1 0 0 1 1 1 1 Surface antigen GHMP_kinases_N PF00288.21 KND97199.1 - 2.3e-13 49.9 0.0 4.5e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KND97199.1 - 3.9e-05 23.7 0.0 9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal p450 PF00067.17 KND97200.1 - 7.3e-99 331.3 0.0 8.4e-99 331.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HLH PF00010.21 KND97201.1 - 3.5e-17 61.8 0.1 7e-17 60.8 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3752 PF12572.3 KND97201.1 - 0.019 15.0 3.5 0.065 13.3 2.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3752) Senescence_reg PF04520.8 KND97201.1 - 0.39 11.2 3.9 0.88 10.0 2.7 1.6 1 1 0 1 1 1 0 Senescence regulator CCDC32 PF14989.1 KND97201.1 - 1.3 8.8 5.1 0.14 11.9 0.2 1.9 2 1 0 2 2 2 0 Coiled-coil domain containing 32 NAD_binding_6 PF08030.7 KND97202.1 - 3.5e-24 85.4 0.0 5.2e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KND97202.1 - 1.3e-21 76.4 0.0 2.9e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KND97202.1 - 2.6e-21 75.9 12.5 2.6e-21 75.9 8.7 2.5 2 1 1 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 KND97202.1 - 0.027 15.0 0.0 12 6.5 0.0 2.5 1 1 0 2 2 2 0 Oxidoreductase NAD-binding domain CFEM PF05730.6 KND97202.1 - 0.065 13.0 2.0 0.11 12.2 1.4 1.3 1 0 0 1 1 1 0 CFEM domain Methyltransf_11 PF08241.7 KND97205.1 - 0.0062 17.0 0.0 0.028 14.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND97205.1 - 0.057 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ARGLU PF15346.1 KND97205.1 - 0.071 12.8 5.2 0.12 12.1 3.6 1.3 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Peptidase_M16_C PF05193.16 KND97206.1 - 2.4e-33 115.3 0.0 5.4e-32 110.9 0.0 2.3 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KND97206.1 - 7.2e-33 113.4 0.0 1.2e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) PAP_central PF04928.12 KND97207.1 - 1.3e-109 364.9 0.0 1.7e-109 364.4 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KND97207.1 - 7.9e-50 168.4 0.2 1.7e-49 167.3 0.1 1.6 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KND97207.1 - 3.7e-12 46.4 0.1 9.6e-12 45.0 0.1 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Oxysterol_BP PF01237.13 KND97208.1 - 2.3e-90 302.6 0.0 2.9e-90 302.2 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein PI3_PI4_kinase PF00454.22 KND97209.1 - 3.9e-37 127.9 0.2 1.3e-36 126.2 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 KND97209.1 - 1.8e-16 59.5 1.6 6.6e-16 57.7 1.1 2.1 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.15 KND97209.1 - 0.00023 20.4 1.1 0.00072 18.7 0.7 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Sec10 PF07393.6 KND97212.1 - 9.2e-64 215.8 20.7 1.1e-63 215.5 14.3 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Flo11 PF10182.4 KND97216.1 - 1.9e-13 50.2 0.0 4.9e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Flo11 domain Collagen PF01391.13 KND97216.1 - 5.4e-09 35.4 87.7 2.5e-06 26.9 25.4 3.7 1 1 2 3 3 3 2 Collagen triple helix repeat (20 copies) Cpn60_TCP1 PF00118.19 KND97219.1 - 3.6e-149 497.4 5.1 4.2e-149 497.2 3.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_L41 PF05162.8 KND97221.1 - 1.2 8.8 4.1 1.8 8.3 2.4 1.7 1 1 0 1 1 1 0 Ribosomal protein L41 Cyclin_N PF00134.18 KND97222.1 - 1.4e-37 128.0 0.7 1.4e-37 128.0 0.5 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KND97222.1 - 5.6e-07 29.5 0.2 1.8e-06 27.8 0.1 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain Myosin_head PF00063.16 KND97223.1 - 1.5e-240 799.9 8.5 1.5e-240 799.9 5.9 3.2 4 2 0 4 4 4 1 Myosin head (motor domain) AAA_13 PF13166.1 KND97223.1 - 2.3e-05 23.0 20.2 2.3e-05 23.0 14.0 6.9 3 2 4 7 7 7 3 AAA domain Myosin_N PF02736.14 KND97223.1 - 0.0089 15.6 0.7 0.021 14.4 0.5 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Sugar_tr PF00083.19 KND97225.1 - 3e-38 131.5 16.5 4.3e-38 131.0 11.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND97225.1 - 2.9e-20 72.2 18.2 4.6e-20 71.6 12.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily PAP2 PF01569.16 KND97226.1 - 3.1e-17 62.4 3.1 3.1e-17 62.4 2.2 1.8 2 0 0 2 2 2 1 PAP2 superfamily TauE PF01925.14 KND97226.1 - 1.3 8.3 8.2 0.15 11.4 2.0 2.0 2 1 0 2 2 2 0 Sulfite exporter TauE/SafE S-AdoMet_synt_C PF02773.11 KND97228.1 - 2.7e-76 253.8 0.2 5.5e-76 252.9 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 KND97228.1 - 1.9e-47 160.1 0.0 3.7e-47 159.1 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 KND97228.1 - 2.5e-43 146.3 0.1 5.3e-43 145.3 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain MRC1 PF09444.5 KND97230.1 - 1.5e-42 145.3 21.2 1.5e-42 145.3 14.7 8.0 6 3 4 10 10 10 1 MRC1-like domain KH_3 PF13014.1 KND97233.1 - 0.054 13.1 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 KH domain BLOC1_2 PF10046.4 KND97234.1 - 0.029 14.4 1.8 0.029 14.4 1.3 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-Q PF13094.1 KND97234.1 - 0.032 14.2 7.1 0.039 13.9 4.9 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Prefoldin_2 PF01920.15 KND97234.1 - 0.11 12.2 8.5 0.2 11.4 5.9 1.4 1 1 0 1 1 1 0 Prefoldin subunit Spore_III_AB PF09548.5 KND97234.1 - 0.14 11.8 6.1 0.17 11.6 4.2 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DASH_Dam1 PF08653.5 KND97234.1 - 0.16 11.7 0.2 0.3 10.8 0.2 1.5 1 0 0 1 1 1 0 DASH complex subunit Dam1 Tox-URI2 PF15653.1 KND97234.1 - 0.21 11.8 6.2 0.79 9.9 4.3 1.9 1 1 0 1 1 1 0 URI fold toxin 2 YPEB PF14620.1 KND97234.1 - 0.59 9.0 6.2 0.71 8.8 4.3 1.0 1 0 0 1 1 1 0 YpeB sporulation V-SNARE PF05008.10 KND97234.1 - 0.6 10.3 11.9 0.8 9.9 1.3 2.7 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus SLX9 PF15341.1 KND97234.1 - 0.66 10.4 14.4 0.74 10.2 10.0 1.1 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Peptidase_C6 PF00851.13 KND97234.1 - 0.68 8.4 3.7 0.73 8.3 2.6 1.1 1 0 0 1 1 1 0 Helper component proteinase DUF3573 PF12097.3 KND97234.1 - 1.2 7.6 4.2 1.2 7.6 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF1640 PF07798.6 KND97234.1 - 1.3 9.0 8.3 1.5 8.8 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Tnp_P_element PF12017.3 KND97234.1 - 1.3 8.2 4.5 1.2 8.3 2.3 1.6 1 1 1 2 2 2 0 Transposase protein DUF1515 PF07439.6 KND97234.1 - 1.4 8.7 5.9 0.83 9.4 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) FAM75 PF14650.1 KND97234.1 - 1.7 7.9 8.5 1.9 7.7 5.9 1.0 1 0 0 1 1 1 0 FAM75 family Corona_nucleoca PF00937.13 KND97234.1 - 2.3 7.0 10.2 2.6 6.9 7.1 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein AAA_23 PF13476.1 KND97234.1 - 2.9 8.1 7.9 3.5 7.9 5.5 1.1 1 0 0 1 1 1 0 AAA domain DOR PF14839.1 KND97234.1 - 3.6 7.2 7.2 4.6 6.9 5.0 1.1 1 0 0 1 1 1 0 DOR family FAM217 PF15344.1 KND97234.1 - 4.1 6.8 9.4 4.6 6.7 6.5 1.0 1 0 0 1 1 1 0 FAM217 family WD40 PF00400.27 KND97235.1 - 4.5e-16 58.0 5.2 0.019 14.8 0.0 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat PQQ_2 PF13360.1 KND97235.1 - 0.00015 21.2 0.8 0.0034 16.8 0.1 2.8 1 1 1 2 2 2 1 PQQ-like domain PQQ PF01011.16 KND97235.1 - 0.0014 18.0 0.2 0.98 9.0 0.0 3.3 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_3 PF13570.1 KND97235.1 - 0.32 11.3 9.8 3.9 7.8 0.0 5.4 5 2 1 6 6 6 0 PQQ-like domain DNA_primase_S PF01896.14 KND97237.1 - 2.3e-52 176.6 0.5 4.2e-52 175.8 0.4 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Cellulase PF00150.13 KND97238.1 - 2.6e-17 62.9 0.1 1.2e-07 31.2 0.0 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) HA2 PF04408.18 KND97240.1 - 1.8e-26 92.1 0.2 8.5e-26 89.9 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KND97240.1 - 1.2e-20 73.4 0.0 2.8e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KND97240.1 - 2.5e-12 46.4 0.0 5.8e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 KND97240.1 - 1.8e-11 43.9 0.1 4.5e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 KND97240.1 - 3.5e-06 26.6 0.3 7.8e-06 25.4 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KND97240.1 - 5.6e-05 23.2 0.0 0.00015 21.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KND97240.1 - 0.0013 18.6 0.2 0.036 13.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KND97240.1 - 0.0036 17.5 0.1 0.28 11.4 0.1 2.8 1 1 0 1 1 1 1 ABC transporter AAA_19 PF13245.1 KND97240.1 - 0.0045 16.7 0.0 0.013 15.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 KND97240.1 - 0.0046 15.9 0.0 0.01 14.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein NB-ARC PF00931.17 KND97240.1 - 0.0069 15.2 0.0 0.014 14.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Miro PF08477.8 KND97240.1 - 0.013 16.0 0.3 0.062 13.8 0.2 2.2 1 1 0 1 1 1 0 Miro-like protein KaiC PF06745.8 KND97240.1 - 0.017 14.2 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 KND97240.1 - 0.028 13.8 0.0 0.06 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 KND97240.1 - 0.085 12.2 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Proteasome PF00227.21 KND97241.1 - 8.8e-34 116.4 0.0 1e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Lum_binding PF00677.12 KND97242.1 - 2.4e-38 129.8 5.8 1.1e-19 70.0 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain TMEM238 PF15125.1 KND97244.1 - 0.29 11.0 2.0 10 6.1 0.0 2.1 1 1 1 2 2 2 0 TMEM238 protein family ATP-synt_8 PF00895.15 KND97247.1 - 0.71 10.1 2.8 1.2 9.3 2.0 1.6 1 1 0 1 1 1 0 ATP synthase protein 8 QCR10 PF09796.4 KND97249.1 - 5.1 6.8 5.9 7.5 6.2 4.0 1.4 1 1 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) LicD PF04991.8 KND97250.1 - 1e-42 146.5 1.3 2.9e-42 145.1 0.0 2.3 2 0 0 2 2 2 1 LicD family Phytase PF02333.10 KND97250.1 - 0.01 14.5 0.1 0.016 13.9 0.1 1.2 1 0 0 1 1 1 0 Phytase FerA PF08165.6 KND97252.1 - 0.06 13.0 0.1 0.083 12.5 0.1 1.2 1 0 0 1 1 1 0 FerA (NUC095) domain Thiolase_N PF00108.18 KND97253.1 - 3.3e-88 295.0 1.0 5.5e-88 294.3 0.7 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KND97253.1 - 5.5e-46 154.9 0.5 1.2e-45 153.9 0.4 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KND97253.1 - 0.0001 21.9 0.5 0.00082 18.9 0.1 2.4 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain SelA PF03841.8 KND97253.1 - 0.14 10.8 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase Gly-zipper_OmpA PF13436.1 KND97255.1 - 0.015 14.9 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain MFS_1 PF07690.11 KND97259.1 - 1.1e-11 44.0 39.6 2.8e-10 39.4 27.5 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily His_Phos_2 PF00328.17 KND97262.1 - 1.3e-43 149.6 0.0 1.6e-43 149.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 KND97262.1 - 0.13 12.3 0.0 0.79 9.7 0.0 1.9 2 1 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) DUF4228 PF14009.1 KND97264.1 - 0.3 11.2 3.1 0.13 12.4 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) TPR_11 PF13414.1 KND97266.1 - 1.3e-09 37.5 10.4 2.6e-07 30.1 0.2 4.5 5 1 0 5 5 5 2 TPR repeat TPR_2 PF07719.12 KND97266.1 - 2e-06 27.2 7.4 0.14 12.1 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KND97266.1 - 5.5e-06 26.5 4.9 2.6 8.8 0.1 5.8 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KND97266.1 - 2.6e-05 24.7 4.4 0.059 14.0 0.0 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 KND97266.1 - 7.5e-05 22.1 4.7 0.085 12.5 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 KND97266.1 - 0.0014 18.2 4.9 8 6.4 0.1 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KND97266.1 - 0.0027 17.6 6.3 0.36 10.8 0.5 4.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KND97266.1 - 0.023 14.8 3.9 0.13 12.5 0.0 4.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 KND97266.1 - 0.16 11.8 2.3 25 4.9 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 KND97266.1 - 0.17 12.2 0.2 0.17 12.2 0.1 5.0 4 2 1 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.20 KND97267.1 - 1.9e-37 128.8 0.6 3.1e-37 128.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND97267.1 - 6.9e-27 94.1 0.0 1.1e-26 93.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KND97267.1 - 1.9e-05 23.8 0.1 5.2e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KND97267.1 - 0.16 11.6 0.5 5.6 6.6 0.1 2.8 3 0 0 3 3 3 0 Phosphotransferase enzyme family Siah-Interact_N PF09032.6 KND97267.1 - 6.4 6.9 14.5 17 5.5 0.3 3.1 2 0 0 2 2 2 0 Siah interacting protein, N terminal ORC2 PF04084.9 KND97268.1 - 2.6e-102 342.0 0.5 3.4e-102 341.6 0.3 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 TFIIS_C PF01096.13 KND97269.1 - 5.6e-22 77.0 5.3 1.3e-21 75.8 1.6 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) zinc_ribbon_5 PF13719.1 KND97269.1 - 0.00055 19.4 5.0 0.03 13.9 0.2 2.8 3 0 0 3 3 3 2 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 KND97269.1 - 0.00095 18.9 1.5 0.085 12.6 0.1 2.3 2 0 0 2 2 2 2 PhnA Zinc-Ribbon zinc_ribbon_4 PF13717.1 KND97269.1 - 0.0034 17.0 7.7 0.034 13.8 0.4 2.8 3 0 0 3 3 3 2 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 KND97269.1 - 0.0051 16.5 1.2 0.06 13.1 0.2 2.3 2 0 0 2 2 2 1 Transposase zinc-ribbon domain RNA_POL_M_15KD PF02150.11 KND97269.1 - 0.085 12.5 2.5 0.15 11.7 0.0 2.5 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Baculo_LEF5_C PF11792.3 KND97269.1 - 0.14 11.5 0.3 0.25 10.7 0.2 1.5 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain zf-H2C2_2 PF13465.1 KND97269.1 - 0.73 10.2 6.3 1 9.8 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger double domain IBR PF01485.16 KND97269.1 - 3 7.8 6.5 46 3.9 0.0 2.7 2 1 0 2 2 2 0 IBR domain DUF4379 PF14311.1 KND97269.1 - 4.7 7.1 6.2 6.1 6.7 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4379) Lactamase_B_2 PF12706.2 KND97270.1 - 1.2e-09 37.9 0.0 3.7e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KND97270.1 - 0.014 15.0 0.0 0.038 13.6 0.0 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily RRM_1 PF00076.17 KND97271.1 - 0.0017 17.9 0.7 0.01 15.4 0.0 2.7 3 1 1 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bunya_RdRp PF04196.7 KND97271.1 - 0.16 9.9 0.0 0.2 9.6 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase OSTbeta PF15048.1 KND97271.1 - 1.3 9.1 6.9 0.074 13.1 0.9 1.8 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein DUF2428 PF10350.4 KND97272.1 - 4.3e-45 153.7 0.0 9.1e-45 152.6 0.0 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT_2 PF13646.1 KND97272.1 - 0.00015 21.9 1.1 0.31 11.3 0.0 4.7 6 0 0 6 6 6 2 HEAT repeats HEAT PF02985.17 KND97272.1 - 0.014 15.4 9.0 5.1 7.4 0.0 6.0 6 0 0 6 6 6 0 HEAT repeat MFS_1 PF07690.11 KND97273.1 - 6.1e-15 54.7 29.5 7.9e-09 34.6 10.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND97273.1 - 2.3e-05 23.1 6.0 2.3e-05 23.1 4.1 2.9 2 2 1 3 3 3 1 Sugar (and other) transporter PspB PF06667.7 KND97273.1 - 0.12 12.3 0.0 0.43 10.5 0.0 2.0 1 0 0 1 1 1 0 Phage shock protein B Thy1 PF02511.10 KND97275.1 - 0.039 13.2 0.0 0.04 13.2 0.0 1.0 1 0 0 1 1 1 0 Thymidylate synthase complementing protein PapJ PF14855.1 KND97276.1 - 0.12 11.8 0.4 0.13 11.6 0.2 1.0 1 0 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone SNF2_N PF00176.18 KND97278.1 - 6.2e-56 189.3 0.0 8.5e-56 188.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KND97278.1 - 7.6e-10 38.9 0.0 1.9e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KND97278.1 - 7.2e-09 35.3 0.0 1.7e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KND97278.1 - 8.5e-08 31.8 0.0 1.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ank_5 PF13857.1 KND97279.1 - 3.2e-05 24.0 0.0 6.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KND97279.1 - 0.0018 18.5 0.1 0.0035 17.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KND97279.1 - 0.0026 17.4 0.1 0.0066 16.1 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeat DUF656 PF04920.7 KND97279.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF656) URO-D PF01208.12 KND97281.1 - 6.4e-107 357.4 0.0 7.7e-107 357.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Peptidase_M28 PF04389.12 KND97282.1 - 2.3e-31 108.9 0.0 4.4e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.9 KND97282.1 - 0.0037 16.0 0.0 0.016 13.9 0.0 1.8 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.23 KND97282.1 - 0.0059 16.1 0.0 0.012 15.1 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Pkinase PF00069.20 KND97284.1 - 2.5e-65 220.2 0.0 2.9e-65 219.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND97284.1 - 2.4e-38 131.6 0.0 2.9e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND97284.1 - 2e-07 30.3 0.0 8.4e-07 28.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 KND97284.1 - 0.005 16.1 0.0 0.0077 15.5 0.0 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 KND97284.1 - 0.0055 15.7 0.0 0.0085 15.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SCA7 PF08313.7 KND97285.1 - 5.8e-33 112.3 0.7 5.8e-33 112.3 0.5 2.5 3 0 0 3 3 3 1 SCA7, zinc-binding domain RR_TM4-6 PF06459.7 KND97285.1 - 3.5 7.4 29.5 3.8 7.3 4.6 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 WD40 PF00400.27 KND97287.1 - 0.00043 20.0 0.2 0.0068 16.2 0.1 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat Bacteriocin_IIi PF11758.3 KND97287.1 - 0.022 14.3 0.2 0.072 12.7 0.1 1.9 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin SSP160 PF06933.6 KND97288.1 - 2.4 6.0 4.6 2.5 5.9 3.2 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 HIG_1_N PF04588.8 KND97289.1 - 1.5e-05 24.6 0.2 3.9e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF1510 PF07423.6 KND97289.1 - 0.048 13.0 7.8 0.1 11.9 5.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Sarcoglycan_2 PF05510.8 KND97289.1 - 0.089 11.0 2.5 0.17 10.1 1.7 1.5 1 1 0 1 1 1 0 Sarcoglycan alpha/epsilon NicO PF03824.11 KND97289.1 - 0.089 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein Med19 PF10278.4 KND97289.1 - 0.74 9.4 12.6 1.2 8.7 8.7 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Peptidase_S49_N PF08496.5 KND97289.1 - 1.4 8.7 7.1 2.8 7.7 4.9 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal IncA PF04156.9 KND97289.1 - 5.7 6.4 11.3 0.47 10.0 4.3 1.8 2 0 0 2 2 2 0 IncA protein DUF1168 PF06658.7 KND97290.1 - 0.28 10.7 7.9 0.28 10.7 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Pex24p PF06398.6 KND97292.1 - 3e-72 243.4 13.7 3.4e-72 243.2 9.5 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Cgr1 PF03879.9 KND97293.1 - 1.8e-35 121.3 34.4 2.2e-35 121.1 23.9 1.1 1 0 0 1 1 1 1 Cgr1 family PRP1_N PF06424.7 KND97293.1 - 0.17 12.2 10.5 0.18 12.0 7.3 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal TBP PF00352.16 KND97294.1 - 8.5e-70 230.1 0.1 9.8e-35 117.7 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KND97294.1 - 0.00015 21.7 0.0 0.57 10.2 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Exo_endo_phos PF03372.18 KND97295.1 - 6.2e-16 59.0 0.0 1.5e-15 57.8 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KND97295.1 - 3.1e-09 36.4 0.0 0.0032 17.0 0.0 2.5 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase zf-GRF PF06839.7 KND97295.1 - 5.4e-08 32.6 3.8 1.1e-07 31.5 2.6 1.6 1 0 0 1 1 1 1 GRF zinc finger Pox_A_type_inc PF04508.7 KND97296.1 - 3.5 7.6 18.2 4.1 7.4 1.2 4.7 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Cohesin_load PF10345.4 KND97297.1 - 4.1e-68 230.0 19.3 5.1e-68 229.7 13.4 1.0 1 0 0 1 1 1 1 Cohesin loading factor SNAP PF14938.1 KND97297.1 - 0.0037 16.4 4.0 0.0098 15.0 1.9 2.1 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KND97297.1 - 0.02 14.7 5.8 0.17 11.8 0.6 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1214 PF06742.6 KND97297.1 - 0.078 13.4 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1214) TPR_11 PF13414.1 KND97297.1 - 0.82 9.3 8.0 0.096 12.3 0.4 3.2 4 0 0 4 4 4 0 TPR repeat UEV PF05743.8 KND97298.1 - 6e-19 67.9 0.0 1.1e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 KND97298.1 - 1.7e-09 37.1 0.3 1.5e-08 34.1 0.0 2.3 2 0 0 2 2 2 1 Vps23 core domain Uds1 PF15456.1 KND97298.1 - 0.0049 16.8 0.3 0.21 11.6 0.0 2.3 1 1 1 2 2 2 1 Up-regulated During Septation DUF3987 PF13148.1 KND97298.1 - 0.038 12.5 1.0 0.056 12.0 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) TEX13 PF15186.1 KND97298.1 - 0.17 11.4 2.1 0.33 10.5 1.4 1.4 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family CDC37_N PF03234.9 KND97298.1 - 0.23 11.7 5.7 0.45 10.8 3.9 1.4 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Lectin_N PF03954.9 KND97298.1 - 0.41 10.0 3.9 4.5 6.6 0.2 2.4 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain APG6 PF04111.7 KND97298.1 - 0.69 8.8 8.2 1.2 8.0 5.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 AA_permease PF00324.16 KND97302.1 - 1.6e-108 363.0 41.7 2e-108 362.8 28.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND97302.1 - 8.1e-32 110.2 46.6 1e-31 109.9 32.3 1.1 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.17 KND97303.1 - 7.4e-38 130.2 0.0 6.7e-37 127.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 ERO1 PF04137.10 KND97304.1 - 1.6e-110 369.5 0.0 2.2e-110 369.0 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Flocculin_t3 PF13928.1 KND97305.1 - 8.7e-08 32.1 22.0 8.7e-08 32.1 15.3 2.8 3 0 0 3 3 3 1 Flocculin type 3 repeat DUF2574 PF10836.3 KND97305.1 - 0.64 9.7 5.6 1.3 8.7 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) Fungal_trans_2 PF11951.3 KND97306.1 - 1.2e-95 320.3 0.4 1.6e-95 319.9 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND97306.1 - 1.5e-09 37.6 6.9 2.5e-09 36.8 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dak1 PF02733.12 KND97308.1 - 2e-111 371.6 1.2 2.9e-111 371.1 0.8 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KND97308.1 - 1e-46 158.8 2.2 1e-46 158.8 1.5 2.4 2 0 0 2 2 2 1 DAK2 domain Proteasom_Rpn13 PF04683.8 KND97308.1 - 0.15 12.1 0.0 0.5 10.4 0.0 1.8 1 0 0 1 1 1 0 Proteasome complex subunit Rpn13 ubiquitin receptor DAO PF01266.19 KND97309.1 - 2.8e-06 26.4 0.4 0.2 10.5 0.0 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KND97309.1 - 3.9e-06 26.0 0.0 0.00025 20.0 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KND97309.1 - 1.1e-05 25.4 0.0 0.48 10.2 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KND97309.1 - 0.00011 21.9 0.1 0.13 12.0 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KND97309.1 - 0.00037 20.6 0.0 1.9 8.4 0.0 3.7 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND97309.1 - 0.00092 19.5 2.7 0.34 11.3 0.0 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KND97309.1 - 0.028 13.3 0.0 0.96 8.2 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 KND97309.1 - 0.076 12.6 0.4 1.8 8.1 0.0 3.0 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 KND97309.1 - 0.091 12.8 0.7 3.7 7.6 0.0 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KND97309.1 - 0.12 11.4 3.1 2.1 7.3 0.3 2.8 3 0 0 3 3 3 0 FAD binding domain Rtt106 PF08512.7 KND97311.1 - 0.089 12.7 0.0 0.093 12.7 0.0 1.1 1 0 0 1 1 1 0 Histone chaperone Rttp106-like Fungal_trans_2 PF11951.3 KND97314.1 - 3.6e-41 141.0 0.0 4.9e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND97314.1 - 0.00013 21.7 9.5 0.00026 20.8 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arrestin_N PF00339.24 KND97320.1 - 0.00037 20.3 0.2 0.0079 16.0 0.1 2.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain MFS_1 PF07690.11 KND97322.1 - 1.1e-17 63.7 45.1 6e-11 41.6 23.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily S1FA PF04689.8 KND97322.1 - 0.012 15.4 0.0 0.034 14.0 0.0 1.8 1 0 0 1 1 1 0 DNA binding protein S1FA Pox_A14 PF05767.7 KND97322.1 - 0.11 12.4 4.4 0.13 12.1 0.1 3.2 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Zip PF02535.17 KND97323.1 - 1.1e-45 156.0 17.4 1.5e-45 155.5 12.1 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter TFIIF_alpha PF05793.7 KND97327.1 - 0.97 7.7 9.5 1.3 7.2 6.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2946 PF11162.3 KND97327.1 - 1.1 9.5 3.7 6.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Herpes_capsid PF06112.6 KND97327.1 - 1.5 8.8 18.8 2.7 8.0 13.0 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein AF-4 PF05110.8 KND97327.1 - 2.5 5.8 14.1 2.8 5.6 9.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Nop14 PF04147.7 KND97327.1 - 3.2 5.5 4.4 3.2 5.5 3.0 1.1 1 0 0 1 1 1 0 Nop14-like family RAP1 PF07218.6 KND97327.1 - 3.6 5.5 8.6 4.1 5.3 6.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2457 PF10446.4 KND97327.1 - 4.9 5.7 9.2 6.5 5.3 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) tRNA-synt_1_2 PF13603.1 KND97328.1 - 0.011 15.0 0.1 0.022 14.0 0.1 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 CRAL_TRIO PF00650.15 KND97329.1 - 2.2e-26 92.2 1.1 3.2e-26 91.7 0.4 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KND97329.1 - 5.9e-08 32.7 0.3 9.2e-08 32.1 0.2 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1191 PF06697.7 KND97330.1 - 0.016 14.0 0.3 0.02 13.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) FAD_binding_8 PF08022.7 KND97331.1 - 1.1e-20 73.3 0.0 4e-20 71.6 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 KND97331.1 - 2e-17 63.5 0.0 3.1e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KND97331.1 - 1.2e-15 57.7 4.5 1.2e-15 57.7 3.1 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component Glyco_transf_21 PF13506.1 KND97332.1 - 8.7e-16 57.6 0.0 1.1e-10 41.0 0.0 3.2 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 KND97332.1 - 6.6e-12 45.7 0.0 9.2e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KND97332.1 - 3.8e-05 23.4 0.2 0.00029 20.5 0.2 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 2 DUF4131 PF13567.1 KND97332.1 - 0.39 10.1 10.2 0.36 10.2 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2039 PF10217.4 KND97333.1 - 0.068 13.1 2.8 0.082 12.9 2.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Carn_acyltransf PF00755.15 KND97334.1 - 2.7e-181 603.6 0.1 3.1e-181 603.4 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF2315 PF10231.4 KND97334.1 - 0.39 10.6 3.3 1.4 8.8 0.1 2.8 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2315) ATG11 PF10377.4 KND97335.1 - 1.1e-31 109.3 1.5 3.6e-31 107.7 0.0 2.8 2 0 0 2 2 2 1 Autophagy-related protein 11 HALZ PF02183.13 KND97335.1 - 0.0095 15.6 24.6 0.54 10.0 2.8 5.4 3 1 0 4 4 4 3 Homeobox associated leucine zipper Pribosyltran_N PF13793.1 KND97336.1 - 1.4e-41 140.9 0.3 1.5e-39 134.3 0.0 2.3 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KND97336.1 - 3.8e-39 134.3 0.5 8.2e-36 123.4 0.2 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KND97336.1 - 2.8e-13 49.6 0.9 6.6e-13 48.4 0.2 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KND97336.1 - 0.0011 18.2 0.1 0.002 17.3 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 KND97336.1 - 0.089 12.0 0.1 5.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Phosphoribosyl transferase ILVD_EDD PF00920.16 KND97337.1 - 6.8e-207 688.0 0.1 7.8e-207 687.8 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family HMGL-like PF00682.14 KND97339.1 - 2.5e-74 249.9 0.2 3.6e-74 249.4 0.1 1.2 1 0 0 1 1 1 1 HMGL-like ADP_PFK_GK PF04587.10 KND97339.1 - 0.015 13.5 0.0 0.024 12.8 0.0 1.2 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region DUF2416 PF10315.4 KND97340.1 - 0.07 13.3 0.4 1.3 9.2 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2416) PepSY_TM_2 PF13703.1 KND97340.1 - 0.13 12.4 0.6 0.34 11.0 0.4 1.6 1 1 0 1 1 1 0 PepSY-associated TM helix DUF1218 PF06749.7 KND97340.1 - 1.1 9.7 4.6 3.3 8.2 3.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1218) EXS PF03124.9 KND97341.1 - 2.1e-96 322.9 27.2 2.8e-96 322.5 18.9 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 KND97341.1 - 2e-51 175.4 12.4 2e-51 175.4 8.6 2.1 2 0 0 2 2 2 1 SPX domain Abhydrolase_6 PF12697.2 KND97342.1 - 3.5e-28 99.0 0.0 6.2e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND97342.1 - 8.7e-17 61.2 0.0 1.7e-16 60.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND97342.1 - 1.8e-15 57.0 0.0 2.9e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DSPc PF00782.15 KND97342.1 - 1.1e-09 37.9 0.0 7.8e-09 35.2 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DUF2305 PF10230.4 KND97342.1 - 4.4e-08 32.8 0.0 6.7e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 KND97342.1 - 4.5e-07 29.6 0.2 3e-06 26.9 0.1 2.3 2 1 0 2 2 2 1 PGAP1-like protein DUF900 PF05990.7 KND97342.1 - 0.0012 18.2 0.1 0.0035 16.6 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.8 KND97342.1 - 0.0021 17.6 0.0 0.0052 16.3 0.0 1.6 1 0 0 1 1 1 1 Serine hydrolase Hydrolase_4 PF12146.3 KND97342.1 - 0.0031 17.3 0.0 0.025 14.4 0.0 2.2 2 0 0 2 2 2 1 Putative lysophospholipase Y_phosphatase PF00102.22 KND97342.1 - 0.004 16.5 0.0 0.01 15.1 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase BAAT_C PF08840.6 KND97342.1 - 0.0075 15.9 0.0 0.19 11.4 0.0 2.2 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 KND97342.1 - 0.018 14.6 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PTPlike_phytase PF14566.1 KND97342.1 - 0.018 15.0 0.1 0.054 13.5 0.1 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate Abhydrolase_2 PF02230.11 KND97342.1 - 0.021 14.2 0.1 0.83 9.0 0.1 2.8 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase LCAT PF02450.10 KND97342.1 - 0.027 13.4 0.1 0.14 11.1 0.0 2.0 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Y_phosphatase3 PF13350.1 KND97342.1 - 0.099 12.8 0.0 0.4 10.9 0.0 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family DUF2338 PF10100.4 KND97342.1 - 0.13 10.6 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) DUF3089 PF11288.3 KND97342.1 - 0.15 11.1 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) E1-E2_ATPase PF00122.15 KND97343.1 - 9.7e-26 90.2 5.5 1.6e-25 89.4 0.3 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KND97343.1 - 3.3e-13 50.5 0.0 1.4e-12 48.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KND97343.1 - 5.4e-11 43.0 0.0 1.3e-10 41.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KND97343.1 - 1.4e-07 31.3 0.0 4.6e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KND97343.1 - 0.0083 15.7 0.3 0.034 13.7 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PT-HINT PF07591.6 KND97345.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Pretoxin HINT domain ATP-synt_ab PF00006.20 KND97347.1 - 1.5e-70 237.0 0.0 2.1e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KND97347.1 - 5.3e-27 94.5 0.5 1.3e-26 93.3 0.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain FmdE PF02663.9 KND97347.1 - 0.094 12.6 0.0 0.32 10.9 0.0 1.9 1 1 1 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon AAA_25 PF13481.1 KND97347.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF2089 PF09862.4 KND97348.1 - 0.028 14.1 0.7 0.068 12.9 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) Macoilin PF09726.4 KND97348.1 - 0.92 7.7 16.4 1.3 7.2 11.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Peptidase_M1 PF01433.15 KND97350.1 - 8.9e-141 469.4 0.1 1.3e-140 468.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KND97350.1 - 1.2e-86 290.9 3.5 2.1e-86 290.1 0.9 2.1 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KND97350.1 - 6.5e-19 68.2 0.1 1.6e-18 66.9 0.1 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2808 PF10989.3 KND97350.1 - 0.0032 17.0 0.0 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2808) HEAT_2 PF13646.1 KND97350.1 - 0.043 14.0 0.0 0.18 12.0 0.0 2.1 1 1 1 2 2 2 0 HEAT repeats Rhodanese PF00581.15 KND97351.1 - 1e-08 35.5 0.0 1.3e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Ish1 PF10281.4 KND97351.1 - 0.019 15.0 0.1 0.078 13.0 0.0 2.0 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Rotamase PF00639.16 KND97352.1 - 8.3e-23 80.9 0.0 1.2e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 KND97352.1 - 6.1e-18 65.1 0.0 8.3e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 KND97352.1 - 5.5e-10 38.9 3.3 1.1e-09 38.0 2.3 1.5 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 KND97352.1 - 2e-07 31.6 0.0 3e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain ADK PF00406.17 KND97353.1 - 6.7e-45 152.6 0.0 8.9e-45 152.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 KND97353.1 - 1.5e-07 31.7 0.0 2.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KND97353.1 - 7.3e-07 29.1 0.0 1.7e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KND97353.1 - 7.7e-06 26.7 0.0 1.2e-05 26.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KND97353.1 - 0.039 13.3 1.0 0.77 9.1 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase SRP54 PF00448.17 KND97353.1 - 0.099 12.0 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Pkinase PF00069.20 KND97355.1 - 2.5e-06 26.8 0.0 4.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Cyclin PF08613.6 KND97356.1 - 5.8e-06 26.7 0.3 9.6e-06 26.0 0.2 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KND97356.1 - 7.5e-05 22.2 0.5 0.00012 21.6 0.3 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain AICARFT_IMPCHas PF01808.13 KND97357.1 - 0.018 14.1 0.3 0.02 13.9 0.2 1.1 1 0 0 1 1 1 0 AICARFT/IMPCHase bienzyme NAP PF00956.13 KND97358.1 - 4.1e-86 288.0 16.2 4.1e-86 288.0 11.2 1.8 3 0 0 3 3 3 1 Nucleosome assembly protein (NAP) Sigma70_ner PF04546.8 KND97358.1 - 0.0044 16.6 7.4 0.0044 16.6 5.1 3.6 3 1 0 4 4 4 1 Sigma-70, non-essential region Prothymosin PF03247.9 KND97358.1 - 0.72 10.0 49.9 0.076 13.1 10.8 3.6 3 0 0 3 3 3 0 Prothymosin/parathymosin family ABC_membrane_2 PF06472.10 KND97359.1 - 6.6e-90 301.0 8.8 1.1e-89 300.3 6.1 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KND97359.1 - 4.4e-18 65.8 0.0 1.5e-17 64.1 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.1 KND97359.1 - 1e-05 25.9 1.9 1e-05 25.9 1.3 2.5 3 1 0 3 3 3 1 AAA domain SMC_N PF02463.14 KND97359.1 - 0.0085 15.3 0.1 2.9 7.0 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.16 KND97359.1 - 0.015 14.4 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KND97359.1 - 0.05 13.3 0.1 0.5 10.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 KND97359.1 - 0.054 13.6 0.0 0.24 11.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF4131 PF13567.1 KND97360.1 - 0.03 13.7 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MFS_1 PF07690.11 KND97361.1 - 1.2e-38 132.7 18.8 1.2e-38 132.7 13.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily RseC_MucC PF04246.7 KND97361.1 - 0.21 11.1 5.9 2.4 7.7 0.0 3.8 3 1 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC ERGIC_N PF13850.1 KND97361.1 - 1.3 9.0 3.2 8.1 6.4 0.0 3.4 4 0 0 4 4 4 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) UPF0203 PF05254.7 KND97363.1 - 5.5e-06 26.1 2.3 1.2e-05 25.0 1.6 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 KND97363.1 - 0.0013 18.5 2.6 0.0036 17.0 1.8 1.7 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 KND97363.1 - 0.0023 17.7 2.8 0.0089 15.9 0.5 2.0 1 1 1 2 2 2 1 CHCH domain UCR_hinge PF02320.11 KND97363.1 - 0.0089 15.9 0.5 0.011 15.6 0.4 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein COX17 PF05051.8 KND97363.1 - 0.0092 15.9 0.9 0.17 11.8 0.8 2.0 1 1 1 2 2 2 2 Cytochrome C oxidase copper chaperone (COX17) Ndufs5 PF10200.4 KND97363.1 - 0.028 14.3 0.1 0.029 14.3 0.1 1.0 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Macin PF14865.1 KND97363.1 - 0.059 13.4 1.2 0.11 12.6 0.8 1.6 1 1 0 1 1 1 0 Macin Mito_carr PF00153.22 KND97364.1 - 5.7e-59 195.8 3.9 3.9e-19 68.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CBS PF00571.23 KND97365.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 CBS domain M16C_assoc PF08367.6 KND97367.1 - 3.5e-71 238.9 0.9 5.6e-71 238.2 0.6 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 KND97367.1 - 8.6e-16 58.1 0.6 1.3e-09 38.0 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KND97367.1 - 1.8e-08 34.2 0.4 2.7e-06 27.1 0.0 3.1 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) Ribosomal_L33 PF00471.15 KND97368.1 - 0.00019 21.5 0.3 0.00034 20.7 0.2 1.5 1 1 0 1 1 1 1 Ribosomal protein L33 EMP24_GP25L PF01105.19 KND97369.1 - 5.1e-38 130.6 0.0 6.2e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Rad33 PF08730.5 KND97371.1 - 6e-35 120.2 0.6 7.6e-35 119.8 0.4 1.1 1 0 0 1 1 1 1 Rad33 PALP PF00291.20 KND97372.1 - 2.8e-52 177.8 0.1 3.4e-52 177.5 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DOT1 PF08123.8 KND97374.1 - 3.1e-73 245.4 0.1 5e-73 244.7 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 DUF2852 PF11014.3 KND97374.1 - 0.091 12.7 1.9 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) SNF2_N PF00176.18 KND97375.1 - 8.8e-80 267.6 0.8 1.4e-79 266.9 0.5 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 KND97375.1 - 3e-41 139.8 2.8 3e-41 139.8 1.9 2.8 3 0 0 3 3 3 1 SLIDE HAND PF09110.6 KND97375.1 - 5.9e-33 113.6 4.2 5.9e-33 113.6 2.9 4.1 4 0 0 4 4 4 1 HAND Helicase_C PF00271.26 KND97375.1 - 3.6e-16 58.7 0.0 2.6e-15 56.0 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND97375.1 - 2.8e-08 33.8 0.0 2.8e-08 33.8 0.0 4.9 4 2 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KND97375.1 - 7.1e-07 28.8 0.1 2.5e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 KND97375.1 - 0.024 14.0 0.0 0.057 12.8 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 UDG PF03167.14 KND97376.1 - 2.3e-18 66.1 0.1 3.7e-18 65.4 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily OST3_OST6 PF04756.8 KND97377.1 - 2.6e-14 53.1 3.0 3.7e-14 52.6 2.1 1.3 1 0 0 1 1 1 1 OST3 / OST6 family EamA PF00892.15 KND97378.1 - 5.4e-09 36.1 38.9 9e-09 35.4 2.1 4.3 3 2 1 4 4 4 2 EamA-like transporter family UAA PF08449.6 KND97378.1 - 1.3e-07 30.9 7.2 1.3e-07 30.9 5.0 2.0 2 1 1 3 3 3 1 UAA transporter family TPT PF03151.11 KND97378.1 - 2.5e-07 30.4 28.8 5.8e-06 26.0 5.1 3.1 3 0 0 3 3 3 2 Triose-phosphate Transporter family EmrE PF13536.1 KND97378.1 - 0.016 15.3 1.2 0.016 15.3 0.8 4.1 3 2 1 4 4 4 0 Multidrug resistance efflux transporter RNA_pol_Rpb8 PF03870.10 KND97378.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb8 KRE9 PF05390.6 KND97379.1 - 5.4e-31 107.1 12.3 1.1e-30 106.0 8.5 1.6 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 KND97379.1 - 2.6e-17 63.0 1.1 2.6e-17 63.0 0.8 2.5 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ATP_synt_H PF05493.8 KND97380.1 - 0.44 10.6 2.6 0.57 10.2 1.8 1.1 1 0 0 1 1 1 0 ATP synthase subunit H DUF3357 PF11837.3 KND97381.1 - 0.11 12.3 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) KRE9 PF05390.6 KND97382.1 - 1.9e-20 73.1 12.6 2.9e-20 72.6 8.7 1.3 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 KND97382.1 - 8.1e-16 58.2 0.2 8.1e-16 58.2 0.1 2.4 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Mgm101p PF06420.7 KND97384.1 - 9.7e-92 304.9 0.0 1.2e-91 304.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Tim17 PF02466.14 KND97385.1 - 0.0034 17.4 0.6 0.006 16.6 0.4 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Intg_mem_TP0381 PF09529.5 KND97385.1 - 0.062 12.5 0.0 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) MAS20 PF02064.10 KND97386.1 - 8.5e-20 70.8 0.3 1.1e-18 67.2 0.2 2.0 1 1 0 1 1 1 1 MAS20 protein import receptor Cellulase PF00150.13 KND97387.1 - 1.3e-18 67.1 7.0 1.3e-18 67.1 4.9 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Homoserine_dh PF00742.14 KND97388.1 - 1.7e-52 177.6 0.0 2.3e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 KND97388.1 - 3e-19 69.5 0.0 4.7e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 KND97388.1 - 2.4e-05 24.6 0.0 8.5e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KND97388.1 - 0.0076 16.6 0.0 0.023 15.1 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 KND97388.1 - 0.046 13.1 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KND97388.1 - 0.095 12.3 0.9 0.64 9.6 0.2 2.3 1 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KND97388.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3608 PF12257.3 KND97389.1 - 1.6e-127 424.1 0.3 2.5e-127 423.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 KND97389.1 - 1.2e-25 89.0 0.1 3e-25 87.7 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF3847 PF12958.2 KND97389.1 - 0.61 9.8 4.3 1.5 8.6 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) SNO PF01174.14 KND97390.1 - 5.7e-58 195.6 0.0 2.1e-45 154.6 0.0 2.0 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 KND97390.1 - 1.4e-08 34.4 0.0 3.5e-08 33.1 0.0 1.6 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 KND97390.1 - 7.8e-05 22.2 0.0 0.00026 20.5 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DUF4066 PF13278.1 KND97390.1 - 0.0002 20.6 0.0 0.00039 19.7 0.0 1.4 1 0 0 1 1 1 1 Putative amidotransferase Peptidase_S51 PF03575.12 KND97390.1 - 0.0039 16.9 0.0 0.0056 16.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.19 KND97390.1 - 0.02 14.3 0.0 0.03 13.7 0.0 1.5 1 1 0 1 1 1 0 DJ-1/PfpI family SOR_SNZ PF01680.12 KND97392.1 - 2.1e-104 347.6 2.3 2.9e-104 347.1 1.6 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 KND97392.1 - 1.6e-11 43.7 1.3 5.7e-09 35.4 0.0 2.5 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 KND97392.1 - 0.00048 19.0 0.2 0.051 12.4 0.0 2.4 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.9 KND97392.1 - 0.0034 16.3 0.2 0.018 14.0 0.0 2.1 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase Ribosomal_S5_C PF03719.10 KND97392.1 - 0.0056 15.9 0.0 0.51 9.6 0.0 2.4 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain IGPS PF00218.16 KND97392.1 - 0.03 13.3 0.0 0.15 11.1 0.0 2.0 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase His_biosynth PF00977.16 KND97392.1 - 0.039 13.2 0.0 0.3 10.3 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein NMO PF03060.10 KND97392.1 - 0.051 12.7 1.7 0.091 11.8 0.0 2.1 2 1 0 2 2 2 0 Nitronate monooxygenase Peroxin-22 PF12827.2 KND97393.1 - 1e-32 112.2 0.4 1.4e-32 111.8 0.3 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis protein family RasGEF PF00617.14 KND97394.1 - 3.3e-46 157.3 1.1 9.8e-46 155.8 0.7 1.9 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KND97394.1 - 3.2e-14 52.8 3.8 3.2e-14 52.8 2.6 3.3 2 1 0 2 2 2 1 RasGEF N-terminal motif SLX9 PF15341.1 KND97395.1 - 3.9e-12 46.6 1.6 4.4e-12 46.5 1.1 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Fork_head PF00250.13 KND97396.1 - 2.5e-12 46.6 0.1 7.4e-12 45.1 0.1 1.8 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KND97396.1 - 1.3e-09 37.9 0.1 2.6e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 FHA domain Proteasome PF00227.21 KND97397.1 - 6.1e-49 165.8 0.1 7.4e-49 165.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Ribosomal_L5_C PF00673.16 KND97398.1 - 1.4e-22 79.1 0.0 2.3e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KND97398.1 - 1.5e-19 69.5 0.0 3.4e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L5 BCAS2 PF05700.6 KND97399.1 - 5.2e-11 42.4 2.5 6e-11 42.2 1.8 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) PBP1_TM PF14812.1 KND97399.1 - 2.3 8.5 6.9 0.42 10.9 1.1 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cofilin_ADF PF00241.15 KND97402.1 - 2.3e-21 75.9 0.0 1.5e-09 37.7 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF4317 PF14199.1 KND97402.1 - 0.07 11.9 0.1 0.15 10.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4317) DUF498 PF04430.9 KND97404.1 - 4.7e-16 58.3 0.0 8.3e-16 57.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Pil1 PF13805.1 KND97407.1 - 6.9e-154 510.7 0.2 8.2e-154 510.5 0.1 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 KND97407.1 - 0.0042 16.4 2.1 0.0073 15.6 1.5 1.3 1 0 0 1 1 1 1 FAM92 protein V_ATPase_I PF01496.14 KND97407.1 - 0.22 9.3 1.3 0.28 8.9 0.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DEADboxA PF12343.3 KND97408.1 - 0.12 12.6 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Cold shock protein DEAD box A DUF454 PF04304.8 KND97410.1 - 0.044 13.8 1.4 0.044 13.8 1.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF454) DUF2516 PF10724.4 KND97410.1 - 0.23 11.4 8.0 0.37 10.8 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2516) FtsX PF02687.16 KND97410.1 - 0.4 10.4 13.4 0.61 9.8 9.3 1.3 1 0 0 1 1 1 0 FtsX-like permease family Tmemb_170 PF10190.4 KND97410.1 - 3.9 7.5 10.3 15 5.6 7.1 1.9 1 1 0 1 1 1 0 Putative transmembrane protein 170 FA_desaturase PF00487.19 KND97410.1 - 8 5.8 10.3 11 5.4 6.9 1.5 1 1 0 1 1 1 0 Fatty acid desaturase NfeD PF01957.13 KND97410.1 - 9 6.4 9.7 0.98 9.5 0.5 2.1 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding Peptidase_C48 PF02902.14 KND97412.1 - 1.3e-12 47.7 1.2 3.8e-12 46.2 0.9 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C5 PF00770.13 KND97412.1 - 0.0072 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Adenovirus endoprotease Peptidase_M24 PF00557.19 KND97413.1 - 2.1e-48 164.6 0.0 2.9e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KND97413.1 - 5.5e-31 106.7 0.0 9.5e-31 105.9 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Band_7 PF01145.20 KND97414.1 - 7.5e-25 87.8 6.1 1.2e-24 87.1 4.0 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 KND97414.1 - 0.0059 16.0 1.5 0.0088 15.4 0.8 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2884) YdfA_immunity PF12127.3 KND97414.1 - 0.061 12.2 2.8 0.08 11.8 1.9 1.2 1 0 0 1 1 1 0 SigmaW regulon antibacterial BRF1 PF07741.8 KND97414.1 - 0.22 11.7 1.6 0.4 10.9 1.1 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain MFS_1 PF07690.11 KND97415.1 - 1.4e-46 158.8 52.2 1.3e-44 152.4 36.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND97415.1 - 1.3e-09 37.2 17.1 1.3e-09 37.2 11.9 3.3 2 1 1 4 4 4 1 Sugar (and other) transporter Prenyltransf PF01255.14 KND97418.1 - 0.00026 20.1 0.0 0.035 13.2 0.0 2.1 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase Arf PF00025.16 KND97419.1 - 9.9e-81 269.1 0.1 1.1e-80 268.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KND97419.1 - 2.9e-14 52.6 0.0 3.6e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KND97419.1 - 1.7e-13 50.2 0.0 1.8e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KND97419.1 - 1.1e-11 44.0 0.8 8.7e-09 34.5 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KND97419.1 - 3.4e-11 42.7 0.0 4e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KND97419.1 - 1.4e-08 35.2 0.0 1.9e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KND97419.1 - 3.8e-05 23.6 0.0 5.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KND97419.1 - 0.0026 16.8 0.3 0.0043 16.1 0.2 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 KND97419.1 - 0.03 13.7 0.1 0.21 10.9 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KND97419.1 - 0.084 12.7 0.1 0.14 12.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KND97419.1 - 0.11 11.9 0.1 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ufd2P_core PF10408.4 KND97420.1 - 2.6e-175 584.2 1.4 3.3e-175 583.9 1.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 KND97420.1 - 9.4e-26 89.5 2.0 1.3e-25 89.1 0.4 2.1 2 0 0 2 2 2 1 U-box domain DUF1899 PF08953.6 KND97422.1 - 0.083 12.5 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1899) DeoRC PF00455.17 KND97424.1 - 0.097 12.3 0.0 0.097 12.3 0.0 1.0 1 0 0 1 1 1 0 DeoR C terminal sensor domain DUF3133 PF11331.3 KND97425.1 - 0.093 12.3 0.6 0.093 12.3 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) AA_permease PF00324.16 KND97427.1 - 4.2e-130 434.2 42.1 5.1e-130 434.0 29.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND97427.1 - 3e-36 124.8 43.4 3.7e-36 124.5 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3591 PF12157.3 KND97428.1 - 2.6e-184 612.8 9.9 1.9e-183 610.0 6.8 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 KND97428.1 - 1.4e-07 31.0 2.5 4.8e-07 29.3 1.7 1.9 1 0 0 1 1 1 1 Zinc knuckle RNase_T PF00929.19 KND97430.1 - 5.7e-21 75.4 0.1 1e-20 74.6 0.1 1.4 1 0 0 1 1 1 1 Exonuclease Lipase_3 PF01764.20 KND97430.1 - 0.064 12.8 0.0 0.24 11.0 0.0 1.9 1 0 0 1 1 1 0 Lipase (class 3) RNase_T PF00929.19 KND97431.1 - 2.5e-24 86.4 0.8 2.2e-23 83.3 0.1 2.3 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.15 KND97431.1 - 0.0064 15.9 0.5 0.036 13.5 0.3 2.1 1 1 0 1 1 1 1 3'-5' exonuclease Pox_C4_C10 PF03336.8 KND97434.1 - 0.064 12.0 0.2 0.067 11.9 0.1 1.0 1 0 0 1 1 1 0 Poxvirus C4/C10 protein DUF1366 PF07104.6 KND97434.1 - 0.11 12.1 1.1 0.13 11.9 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) DDE_Tnp_1_3 PF13612.1 KND97435.1 - 0.032 13.9 2.1 0.38 10.4 0.0 2.4 2 0 0 2 2 2 0 Transposase DDE domain Lipoprotein_20 PF13942.1 KND97435.1 - 0.11 11.9 2.7 0.12 11.8 0.1 2.1 2 0 0 2 2 2 0 YfhG lipoprotein DUF382 PF04037.8 KND97435.1 - 0.23 11.3 0.1 0.23 11.3 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF382) GTP_EFTU PF00009.22 KND97437.1 - 2.1e-49 167.4 0.0 4.7e-49 166.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KND97437.1 - 1.4e-14 53.6 0.0 4.6e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KND97437.1 - 1.4e-12 47.2 0.0 3.7e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KND97437.1 - 2.2e-07 30.8 0.1 5.8e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 KND97437.1 - 2.6e-05 23.7 0.0 0.0004 19.9 0.0 2.9 2 1 0 2 2 2 1 Elongation factor G, domain IV DEAD PF00270.24 KND97439.1 - 2.5e-41 140.9 0.0 3.6e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND97439.1 - 1.3e-23 82.5 0.0 2.8e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GATase_2 PF00310.16 KND97441.1 - 2e-27 95.8 0.2 8.6e-22 77.3 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KND97441.1 - 3.2e-15 56.2 0.0 6.2e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KND97441.1 - 2.7e-12 46.5 0.0 4.3e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 KND97441.1 - 4e-11 42.7 0.0 7.6e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 KND97441.1 - 2.2e-05 23.3 0.0 3.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II NAC PF01849.13 KND97442.1 - 1.1e-17 63.2 0.3 2.3e-17 62.2 0.2 1.6 1 0 0 1 1 1 1 NAC domain MFS_1 PF07690.11 KND97443.1 - 3.6e-16 58.8 53.4 5.6e-14 51.6 23.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 KND97443.1 - 1.2e-06 28.0 10.2 1.2e-06 28.0 7.1 1.9 2 0 0 2 2 2 1 Nodulin-like DEAD PF00270.24 KND97444.1 - 1.9e-42 144.6 0.5 7.9e-42 142.6 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND97444.1 - 4.5e-25 87.3 0.1 1.1e-24 86.0 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 KND97444.1 - 0.022 13.8 0.3 0.06 12.3 0.0 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit CoA_binding_2 PF13380.1 KND97444.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 CoA binding domain ResIII PF04851.10 KND97444.1 - 0.2 11.4 5.0 0.48 10.2 0.0 3.1 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit RRM_1 PF00076.17 KND97445.1 - 4.9e-09 35.7 0.0 1.1e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND97445.1 - 1.2e-08 34.6 0.2 2.9e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND97445.1 - 0.00025 20.9 0.0 0.00055 19.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AKAP7_RIRII_bdg PF10470.4 KND97445.1 - 0.14 11.9 4.8 0.85 9.4 0.4 2.5 2 0 0 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein PAPA-1 PF04795.7 KND97445.1 - 0.24 12.1 11.2 0.28 11.9 4.9 2.3 2 0 0 2 2 2 0 PAPA-1-like conserved region DUF1923 PF09083.5 KND97448.1 - 0.058 12.8 0.0 0.099 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1923) Speriolin_N PF15058.1 KND97452.1 - 5.1 6.9 11.4 6.6 6.5 7.8 1.3 1 1 0 1 1 1 0 Speriolin N terminus DUF4599 PF15371.1 KND97453.1 - 0.19 11.8 0.7 0.27 11.3 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4599) MFS_1 PF07690.11 KND97455.1 - 2.5e-32 111.9 27.3 2.5e-32 111.9 18.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DpnD-PcfM PF14207.1 KND97455.1 - 0.035 13.8 0.9 0.068 12.9 0.6 1.5 1 0 0 1 1 1 0 DpnD/PcfM-like protein DUF3278 PF11683.3 KND97455.1 - 0.16 11.9 2.9 4.3 7.3 0.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) DUF4064 PF13273.1 KND97455.1 - 0.31 11.1 0.0 0.31 11.1 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) MMPL PF03176.10 KND97455.1 - 0.57 8.8 2.6 0.41 9.3 0.1 1.9 2 0 0 2 2 2 0 MMPL family Nitro_FeMo-Co PF02579.12 KND97456.1 - 0.067 13.2 0.1 0.081 13.0 0.1 1.1 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor Catalase PF00199.14 KND97458.1 - 2.8e-71 240.2 0.4 4.1e-71 239.7 0.3 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KND97458.1 - 1.2e-11 44.3 0.3 1e-10 41.2 0.1 2.3 2 0 0 2 2 2 1 Catalase-related immune-responsive RAI1 PF08652.6 KND97460.1 - 1.5e-27 95.1 0.5 6e-27 93.2 0.0 2.2 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease Sad1_UNC PF07738.8 KND97461.1 - 8.2e-33 113.0 0.1 1.9e-32 111.8 0.1 1.7 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CHDCT2 PF08074.6 KND97461.1 - 0.013 15.2 3.5 0.026 14.2 2.4 1.6 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Maelstrom PF13017.1 KND97461.1 - 0.069 12.6 2.1 0.15 11.5 1.4 1.5 1 0 0 1 1 1 0 piRNA pathway germ-plasm component DEAD PF00270.24 KND97462.1 - 4.9e-32 110.7 0.0 9e-32 109.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND97462.1 - 3e-19 68.6 0.1 5.3e-19 67.8 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND97462.1 - 8.8e-05 22.4 0.0 0.00022 21.1 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 KND97462.1 - 0.057 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain Mso1_Sec1_bdg PF14475.1 KND97463.1 - 4.3e-18 64.4 0.0 7.3e-18 63.6 0.0 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 DUF619 PF04768.8 KND97465.1 - 2.9e-51 173.2 0.0 7.7e-51 171.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 KND97465.1 - 4.8e-29 101.1 0.0 1.1e-28 99.9 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 KND97465.1 - 2.3e-19 69.9 0.0 4.7e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dhC PF02774.13 KND97465.1 - 3.6e-07 30.2 0.1 1.3e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.15 KND97465.1 - 0.00084 19.2 0.1 0.0028 17.5 0.0 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 KND97465.1 - 0.017 15.6 0.0 0.049 14.1 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold BLVR PF06375.6 KND97471.1 - 0.021 14.6 2.3 0.025 14.4 1.6 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) UPF0542 PF15086.1 KND97471.1 - 0.078 12.7 2.0 0.1 12.3 1.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 DUF2962 PF11176.3 KND97473.1 - 3.9e-42 143.4 9.0 4.5e-42 143.2 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) Phage_int_SAM_2 PF12834.2 KND97473.1 - 0.47 10.8 7.3 0.56 10.6 4.1 1.8 2 1 0 2 2 2 0 Phage integrase, N-terminal Peptidase_S49_N PF08496.5 KND97473.1 - 9.6 5.9 7.0 11 5.8 3.1 1.9 1 1 1 2 2 2 0 Peptidase family S49 N-terminal RRP7 PF12923.2 KND97475.1 - 0.0041 17.1 3.4 0.0075 16.2 0.6 2.1 1 1 1 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) Gly-rich_Ago1 PF12764.2 KND97482.1 - 0.074 13.6 0.8 0.1 13.2 0.4 1.3 1 1 0 1 1 1 0 Glycine-rich region of argonaut PTS_2-RNA PF01885.11 KND97483.1 - 8.4e-58 194.7 0.0 9.5e-58 194.5 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Complex1_LYR PF05347.10 KND97484.1 - 1.6e-06 27.7 0.3 2.6e-06 27.1 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KND97484.1 - 5.4e-06 26.5 0.3 8.8e-06 25.8 0.2 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KND97484.1 - 0.026 15.0 0.7 0.04 14.4 0.5 1.5 1 1 0 1 1 1 0 Complex1_LYR-like Plasmid_RAQPRD PF09686.5 KND97484.1 - 0.032 14.3 0.2 0.062 13.3 0.1 1.6 1 1 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Utp8 PF10395.4 KND97485.1 - 1.9e-115 386.6 23.2 5.6e-115 385.1 16.1 1.6 1 1 0 1 1 1 1 Utp8 family VPS11_C PF12451.3 KND97486.1 - 1.6e-16 59.8 0.5 6e-15 54.8 0.1 3.6 3 0 0 3 3 3 1 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.1 KND97486.1 - 0.0015 18.3 3.5 0.0047 16.7 2.4 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KND97486.1 - 0.0023 17.5 4.8 0.0054 16.4 3.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KND97486.1 - 0.0056 16.7 0.9 0.015 15.4 0.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KND97486.1 - 0.021 14.8 4.4 0.06 13.3 3.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PPR PF01535.15 KND97486.1 - 0.026 14.5 0.3 0.13 12.3 0.0 2.4 2 0 0 2 2 2 0 PPR repeat TPR_11 PF13414.1 KND97486.1 - 0.047 13.3 0.1 0.18 11.4 0.0 1.9 1 0 0 1 1 1 0 TPR repeat zf-Apc11 PF12861.2 KND97486.1 - 0.066 13.0 0.2 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.15 KND97486.1 - 0.19 11.2 2.1 0.41 10.2 1.4 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger TPR_8 PF13181.1 KND97486.1 - 0.19 11.5 2.2 5.4 7.0 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KND97486.1 - 0.55 10.2 3.5 1.2 9.2 0.2 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-Nse PF11789.3 KND97486.1 - 1.8 8.1 5.1 1.3 8.5 2.0 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 KND97486.1 - 2.5 7.8 12.7 0.044 13.4 3.6 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KND97486.1 - 3.2 7.5 10.7 0.02 14.5 1.6 1.7 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) Reticulon PF02453.12 KND97488.1 - 7.1e-36 123.3 3.6 9.4e-36 122.9 2.5 1.1 1 0 0 1 1 1 1 Reticulon Methyltransf_4 PF02390.12 KND97489.1 - 1.6e-59 200.3 0.2 1.6e-59 200.3 0.1 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 KND97489.1 - 1.5e-05 25.5 0.0 4.3e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KND97489.1 - 0.00011 21.6 0.0 0.00041 19.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 KND97489.1 - 0.00049 19.7 1.1 0.00056 19.5 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND97489.1 - 0.0011 19.4 0.3 0.0063 16.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND97489.1 - 0.0019 18.2 0.0 0.0034 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KND97489.1 - 0.014 14.4 0.0 0.03 13.3 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FmrO PF07091.6 KND97489.1 - 0.017 14.1 0.0 0.067 12.1 0.0 1.9 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) TraC_F_IV PF11130.3 KND97489.1 - 0.041 13.3 0.0 0.083 12.3 0.0 1.5 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer MetW PF07021.7 KND97489.1 - 0.078 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 KND97489.1 - 0.091 12.4 0.5 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DOT1 PF08123.8 KND97489.1 - 0.095 11.9 0.5 0.38 10.0 0.0 2.1 2 1 1 3 3 3 0 Histone methylation protein DOT1 Methyltransf_25 PF13649.1 KND97489.1 - 0.098 13.0 0.1 0.37 11.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 KND97489.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain ATP-synt_E PF05680.7 KND97489.1 - 5.3 7.0 10.0 2.9 7.8 4.5 2.2 2 0 0 2 2 2 0 ATP synthase E chain Ribosomal_L10 PF00466.15 KND97490.1 - 5.8e-06 26.1 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribonucleas_3_3 PF14622.1 KND97491.1 - 1.9e-23 82.8 0.6 2e-22 79.4 0.1 2.4 2 0 0 2 2 2 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KND97491.1 - 2.3e-21 76.3 0.2 1.7e-20 73.5 0.0 2.6 2 0 0 2 2 2 1 Ribonuclease III domain dsrm PF00035.20 KND97491.1 - 1.4e-11 44.7 0.5 5.7e-05 23.6 0.3 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif DrrA_P4M PF14860.1 KND97491.1 - 0.078 12.7 0.1 0.078 12.7 0.1 2.1 3 0 0 3 3 3 0 DrrA phosphatidylinositol 4-phosphate binding domain TcdA_TcdB PF12919.2 KND97492.1 - 0.14 10.5 0.0 0.19 10.1 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Peptidase_M24 PF00557.19 KND97494.1 - 4.4e-09 36.2 0.0 1.8e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 Metallopeptidase family M24 14-3-3 PF00244.15 KND97495.1 - 5.8e-114 379.0 4.6 7.1e-114 378.7 3.2 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.6 KND97495.1 - 0.00066 19.5 0.2 0.0017 18.2 0.2 1.7 1 0 0 1 1 1 1 Flagellar protein FlaF TPR_12 PF13424.1 KND97495.1 - 0.014 15.3 0.7 0.043 13.7 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Septin PF00735.13 KND97496.1 - 1.9e-115 384.7 0.1 2.8e-115 384.1 0.1 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KND97496.1 - 1.1e-05 25.3 0.0 2.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KND97496.1 - 0.00017 21.1 0.1 0.0035 16.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KND97496.1 - 0.00019 20.6 2.0 0.00043 19.4 0.1 2.3 2 1 0 2 2 2 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 KND97496.1 - 0.001 18.6 0.0 0.0027 17.2 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_24 PF13479.1 KND97496.1 - 0.0025 17.4 0.0 0.0042 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AIG1 PF04548.11 KND97496.1 - 0.0072 15.4 0.1 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 AIG1 family AAA_22 PF13401.1 KND97496.1 - 0.0085 16.2 0.0 0.029 14.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 KND97496.1 - 0.0098 16.3 0.6 0.042 14.3 0.0 2.3 2 1 0 3 3 2 1 Miro-like protein NACHT PF05729.7 KND97496.1 - 0.01 15.4 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 KND97496.1 - 0.051 13.5 0.1 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 KND97496.1 - 0.053 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.21 KND97496.1 - 0.063 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_10 PF12846.2 KND97496.1 - 0.097 12.0 0.3 0.24 10.8 0.1 1.7 1 1 0 1 1 1 0 AAA-like domain KAP_NTPase PF07693.9 KND97496.1 - 0.13 11.1 2.1 0.28 10.1 1.4 1.7 1 1 0 1 1 1 0 KAP family P-loop domain Dynamin_N PF00350.18 KND97496.1 - 1.2 8.9 4.8 20 4.9 0.0 3.0 2 1 1 3 3 3 0 Dynamin family Zn_clus PF00172.13 KND97497.1 - 1.7e-07 31.0 11.0 2.8e-07 30.3 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND97497.1 - 0.036 12.9 2.3 4.2 6.1 0.0 2.7 2 1 1 3 3 3 0 Fungal specific transcription factor domain Metallophos PF00149.23 KND97498.1 - 2.6e-09 36.7 1.7 6.7e-09 35.4 1.1 1.8 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Homeobox PF00046.24 KND97500.1 - 0.0002 20.9 1.1 0.00036 20.1 0.8 1.5 1 0 0 1 1 1 1 Homeobox domain WD40 PF00400.27 KND97502.1 - 4.8e-29 99.1 0.1 1.4e-08 34.3 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat DUF4050 PF13259.1 KND97502.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) DLH PF01738.13 KND97503.1 - 7.8e-30 103.7 0.0 9.7e-30 103.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KND97503.1 - 5.7e-07 29.3 0.0 7.8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 KND97503.1 - 0.0026 17.2 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Peptidase_S9 PF00326.16 KND97503.1 - 0.14 11.3 0.0 0.39 9.9 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family 4F5 PF04419.9 KND97504.1 - 1.8e-08 34.9 16.9 1.8e-08 34.9 11.7 1.7 1 1 0 1 1 1 1 4F5 protein family DUF1204 PF06721.6 KND97504.1 - 0.13 11.5 4.3 0.14 11.3 3.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) Dishevelled PF02377.10 KND97504.1 - 2.2 8.5 4.1 1.6 8.9 2.3 1.3 1 1 0 1 1 1 0 Dishevelled specific domain HDAC4_Gln PF12203.3 KND97504.1 - 2.2 8.2 10.9 2.6 8.0 7.5 1.1 1 0 0 1 1 1 0 Glutamine rich N terminal domain of histone deacetylase 4 DUF4337 PF14235.1 KND97504.1 - 7.4 6.3 7.2 7.1 6.4 5.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ATP-synt_E PF05680.7 KND97504.1 - 8.8 6.3 8.5 10 6.1 5.9 1.1 1 0 0 1 1 1 0 ATP synthase E chain ArsA_ATPase PF02374.10 KND97506.1 - 5.5e-108 360.6 0.2 6.4e-108 360.3 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 KND97506.1 - 4.2e-10 39.3 0.0 6.7e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KND97506.1 - 0.00063 19.7 0.0 0.0017 18.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KND97506.1 - 0.0026 16.6 0.0 0.0053 15.6 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain Fer4_NifH PF00142.13 KND97506.1 - 0.0034 16.6 0.1 0.009 15.2 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family KaiC PF06745.8 KND97506.1 - 0.013 14.5 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 KaiC Zeta_toxin PF06414.7 KND97506.1 - 0.024 13.7 0.0 0.05 12.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 KND97506.1 - 0.079 12.3 0.2 0.14 11.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 KND97506.1 - 0.089 12.2 0.0 0.29 10.5 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PhoH PF02562.11 KND97506.1 - 0.13 11.5 0.0 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.1 KND97506.1 - 0.17 11.6 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain DUF3402 PF11882.3 KND97507.1 - 0.076 12.0 0.0 0.085 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) DUF3112 PF11309.3 KND97508.1 - 2.8e-43 147.4 6.7 2.8e-43 147.4 4.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3112) DUF3040 PF11239.3 KND97508.1 - 0.054 13.5 0.8 0.054 13.5 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) DUF3112 PF11309.3 KND97509.1 - 3.3e-42 143.9 10.0 3.3e-42 143.9 6.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3112) DUF3816 PF12822.2 KND97509.1 - 0.67 9.8 30.0 0.1 12.5 0.5 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3816) DUF4029 PF13221.1 KND97509.1 - 5.6 7.4 9.8 0.2 12.0 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4029) DUF3112 PF11309.3 KND97510.1 - 1e-49 168.3 6.4 1e-49 168.3 4.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3112) CytB6-F_Fe-S PF08802.5 KND97510.1 - 5.4 7.1 6.1 2.4 8.2 1.4 2.4 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit Ctf8 PF09696.5 KND97511.1 - 1e-28 99.5 0.1 1.3e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Ctf8 Y_phosphatase3 PF13350.1 KND97512.1 - 1.7e-43 148.7 0.0 3.4e-43 147.7 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Abhydrolase_5 PF12695.2 KND97512.1 - 7e-13 48.5 0.0 1.3e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Y_phosphatase3C PF13348.1 KND97512.1 - 8.9e-13 48.1 0.2 2.2e-12 46.9 0.2 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Abhydrolase_6 PF12697.2 KND97512.1 - 7.9e-12 45.5 0.1 3.1e-11 43.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KND97512.1 - 5.2e-06 25.8 0.1 3.5e-05 23.1 0.1 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 KND97512.1 - 0.0019 18.0 0.1 0.008 16.0 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Y_phosphatase PF00102.22 KND97512.1 - 0.0064 15.8 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KND97512.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.8 KND97512.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Abhydrolase_1 PF00561.15 KND97512.1 - 0.018 14.5 0.5 3.6 7.0 0.0 2.7 2 1 0 2 2 2 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 KND97512.1 - 0.078 11.8 0.0 0.29 9.9 0.0 1.8 1 1 0 1 1 1 0 Chlorophyllase enzyme DLH PF01738.13 KND97512.1 - 0.082 12.1 0.0 0.22 10.7 0.0 1.6 1 0 0 1 1 1 0 Dienelactone hydrolase family BLVR PF06375.6 KND97513.1 - 0.084 12.6 4.8 0.079 12.7 3.3 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) YgaB PF14182.1 KND97513.1 - 0.28 11.4 3.2 0.32 11.2 2.2 1.1 1 0 0 1 1 1 0 YgaB-like protein EAP30 PF04157.11 KND97514.1 - 5.3e-34 117.3 0.0 6.5e-34 117.0 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family PP-binding PF00550.20 KND97514.1 - 0.034 14.4 0.0 0.66 10.2 0.0 2.6 2 0 0 2 2 2 0 Phosphopantetheine attachment site PseudoU_synth_1 PF01416.15 KND97515.1 - 9.2e-34 116.0 0.0 8.1e-24 84.0 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase DEAD PF00270.24 KND97516.1 - 1.9e-40 138.1 0.1 4.3e-40 136.9 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND97516.1 - 7.3e-20 70.6 0.0 2.8e-19 68.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KND97516.1 - 5.4e-18 64.2 0.4 1.3e-17 63.0 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KND97516.1 - 0.00032 20.6 4.2 0.0011 18.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KND97516.1 - 0.012 15.7 0.2 0.42 10.7 0.1 2.7 1 1 0 1 1 1 0 AAA domain SpoIIIAH PF12685.2 KND97516.1 - 1.6 8.2 12.4 2.7 7.4 8.6 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Transformer PF06495.6 KND97516.1 - 3.2 7.5 6.8 5.8 6.7 4.7 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein APG6 PF04111.7 KND97516.1 - 5.2 6.0 16.4 11 5.0 11.4 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 ThiF PF00899.16 KND97517.1 - 3.1e-09 36.7 0.0 6.2e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 ThiF family SPX PF03105.14 KND97518.1 - 1.1e-35 123.7 10.8 1.5e-35 123.3 7.5 1.2 1 0 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 KND97518.1 - 1.4e-07 31.2 8.4 3.4e-07 30.0 5.8 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KND97518.1 - 2.1e-07 30.6 8.8 4.5e-07 29.5 6.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KND97518.1 - 9e-07 28.4 7.8 2e-06 27.3 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KND97518.1 - 1.8e-06 27.8 10.6 3.7e-06 26.8 7.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KND97518.1 - 1.5e-05 24.5 7.5 2.6e-05 23.8 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KND97518.1 - 2.8e-05 23.7 6.5 0.00011 21.7 4.5 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 KND97518.1 - 0.00013 21.6 9.8 0.00047 19.8 6.9 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.1 KND97518.1 - 0.0014 18.1 2.6 0.0014 18.1 1.8 1.9 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 KND97518.1 - 0.01 15.8 2.8 0.023 14.8 2.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger TerY-C PF15616.1 KND97518.1 - 0.021 14.7 2.6 0.065 13.1 1.8 1.8 1 0 0 1 1 1 0 TerY-C metal binding domain zf-Apc11 PF12861.2 KND97518.1 - 0.035 13.9 3.1 0.07 12.9 2.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 KND97518.1 - 0.2 11.4 3.8 0.48 10.2 2.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-MIZ PF02891.15 KND97518.1 - 1.2 8.7 7.9 3.7 7.1 5.6 1.8 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger Pyr_redox_2 PF07992.9 KND97519.1 - 8.9e-22 77.9 0.0 9e-14 51.8 0.0 3.6 3 1 1 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND97519.1 - 5e-10 39.6 0.0 3.3e-09 37.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KND97519.1 - 3.9e-05 23.8 0.0 0.22 11.5 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DUF1358 PF07096.6 KND97519.1 - 0.002 17.8 0.2 0.027 14.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1358) Mod_r PF07200.8 KND97520.1 - 0.0011 18.9 4.1 0.0017 18.2 2.8 1.4 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF600 PF04634.7 KND97520.1 - 0.33 10.9 3.1 0.39 10.7 0.7 2.0 2 1 1 3 3 3 0 Protein of unknown function, DUF600 Rep_3 PF01051.16 KND97520.1 - 0.57 9.7 5.4 0.81 9.2 3.7 1.3 1 1 0 1 1 1 0 Initiator Replication protein Ank_4 PF13637.1 KND97521.1 - 5e-11 42.8 1.0 0.0021 18.5 0.1 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND97521.1 - 2.1e-09 37.3 0.6 0.0035 17.5 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KND97521.1 - 5.3e-09 36.3 0.5 0.00081 19.6 0.1 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) KilA-N PF04383.8 KND97521.1 - 3.5e-07 29.8 0.0 3.2e-06 26.7 0.0 2.6 1 1 0 1 1 1 1 KilA-N domain Ank_3 PF13606.1 KND97521.1 - 5.8e-07 29.1 1.3 0.12 12.6 0.1 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 KND97521.1 - 5.6e-06 25.8 0.2 0.22 11.3 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat DUF2296 PF10058.4 KND97523.1 - 2.4e-19 68.8 0.3 3.8e-19 68.1 0.2 1.3 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) ALIX_LYPXL_bnd PF13949.1 KND97523.1 - 0.11 11.3 2.4 0.25 10.2 0.4 2.1 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV DivIC PF04977.10 KND97523.1 - 0.18 11.2 1.0 9.8 5.7 0.3 2.9 3 0 0 3 3 3 0 Septum formation initiator NAC PF01849.13 KND97524.1 - 1.8e-17 62.6 1.2 1.8e-17 62.6 0.8 1.9 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 KND97524.1 - 0.00018 21.2 0.0 0.00035 20.3 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Gp_dh_N PF00044.19 KND97524.1 - 0.044 13.7 2.5 0.04 13.8 0.6 1.7 1 1 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain E1-E2_ATPase PF00122.15 KND97525.1 - 3.8e-16 58.8 0.1 5.9e-15 54.9 0.0 2.6 3 0 0 3 3 3 1 E1-E2 ATPase HAD PF12710.2 KND97525.1 - 1.9e-13 51.0 0.3 1.1e-12 48.5 0.1 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KND97525.1 - 7.6e-13 49.3 3.0 9.1e-10 39.3 2.1 3.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KND97525.1 - 2.1e-10 40.4 0.0 5.6e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KND97525.1 - 0.00033 20.3 0.3 0.0011 18.6 0.2 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CPSF100_C PF13299.1 KND97526.1 - 4.3e-25 88.7 0.1 4.3e-25 88.7 0.0 3.0 3 1 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 KND97526.1 - 1.4e-16 60.5 0.0 3.9e-16 59.1 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 KND97526.1 - 0.00016 21.4 0.0 0.00034 20.3 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Ndufs5 PF10200.4 KND97527.1 - 3.9e-05 23.5 0.2 4.4e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CHCH PF06747.8 KND97527.1 - 0.0088 15.9 2.2 0.022 14.6 1.5 1.8 1 1 0 1 1 1 1 CHCH domain COX6B PF02297.12 KND97527.1 - 0.011 15.6 1.2 0.011 15.6 0.9 2.0 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DUF3128 PF11326.3 KND97527.1 - 0.034 14.2 3.4 0.28 11.3 2.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Pet191_N PF10203.4 KND97527.1 - 0.18 11.8 1.3 0.24 11.4 0.9 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 UCR_hinge PF02320.11 KND97527.1 - 0.4 10.6 2.4 5.4 7.0 0.2 2.1 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein CBF PF03914.12 KND97528.1 - 8.8e-28 96.8 2.0 2.9e-27 95.1 1.4 1.9 1 0 0 1 1 1 1 CBF/Mak21 family NOC3p PF07540.6 KND97528.1 - 1.9e-25 88.9 0.5 8e-25 86.9 0.3 2.2 1 0 0 1 1 1 1 Nucleolar complex-associated protein p450 PF00067.17 KND97529.1 - 3.6e-48 164.2 0.0 6.3e-48 163.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 6PGD PF00393.14 KND97530.1 - 4.4e-134 446.2 0.0 5.8e-134 445.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KND97530.1 - 1.3e-52 177.8 0.0 2e-52 177.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KND97530.1 - 0.012 16.0 0.1 0.024 15.0 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 KND97530.1 - 0.015 14.4 0.0 0.034 13.2 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KND97530.1 - 0.03 14.3 0.2 0.12 12.4 0.1 2.0 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.1 KND97530.1 - 0.034 14.1 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Attachment_P66 PF11263.3 KND97531.1 - 0.098 11.6 0.0 0.098 11.6 0.0 1.0 1 0 0 1 1 1 0 Borrelia burgdorferi attachment protein P66 ATP-sulfurylase PF01747.12 KND97532.1 - 1.1e-82 276.5 0.0 1.5e-82 276.1 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 KND97532.1 - 2.4e-48 163.5 0.0 3.9e-48 162.8 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain CTP_transf_2 PF01467.21 KND97532.1 - 0.23 11.4 0.7 0.75 9.8 0.5 1.9 1 1 0 1 1 1 0 Cytidylyltransferase Acid_PPase PF12689.2 KND97534.1 - 1.5e-43 148.3 0.0 1.7e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Ribosomal_L31 PF01197.13 KND97535.1 - 0.056 13.4 0.2 0.72 9.8 0.1 2.7 1 1 0 1 1 1 0 Ribosomal protein L31 DUF2683 PF10884.3 KND97535.1 - 0.081 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) ZZ PF00569.12 KND97535.1 - 5.8 6.5 10.5 18 4.9 7.3 1.8 1 1 0 1 1 1 0 Zinc finger, ZZ type DUF3007 PF11460.3 KND97536.1 - 0.3 11.1 2.6 0.4 10.7 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3007) Syntaxin PF00804.20 KND97536.1 - 0.79 9.9 11.0 0.7 10.0 2.2 2.2 2 0 0 2 2 2 0 Syntaxin ANATO PF01821.13 KND97536.1 - 2.9 8.0 5.8 0.84 9.8 0.4 2.3 2 0 0 2 2 2 0 Anaphylotoxin-like domain DRIM PF07539.7 KND97537.1 - 1.7e-25 89.0 1.9 4.9e-25 87.5 0.3 2.7 2 0 0 2 2 2 1 Down-regulated in metastasis DUF155 PF02582.9 KND97538.1 - 7.5e-57 192.0 1.8 1.3e-56 191.2 1.2 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 MalM PF07148.7 KND97538.1 - 0.036 13.5 0.2 0.069 12.6 0.1 1.4 1 0 0 1 1 1 0 Maltose operon periplasmic protein precursor (MalM) UPF0449 PF15136.1 KND97538.1 - 0.036 14.2 0.0 0.097 12.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Ribonuc_2-5A PF06479.7 KND97538.1 - 0.083 12.7 0.3 2 8.2 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease 2-5A Sugarporin_N PF11471.3 KND97538.1 - 7.1 6.3 6.6 0.6 9.7 1.1 1.8 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension AIM24 PF01987.12 KND97542.1 - 1.3e-09 37.8 0.0 1.9e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 PIP5K PF01504.13 KND97543.1 - 1.9e-84 282.6 0.6 3.4e-84 281.8 0.4 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF1157 PF06636.6 KND97544.1 - 0.019 13.6 0.1 0.026 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1157) Suc_Fer-like PF06999.7 KND97545.1 - 5e-53 180.4 0.0 6.4e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Thioredoxin PF00085.15 KND97546.1 - 2.6e-08 33.4 0.0 9.1e-08 31.7 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin ERp29_N PF07912.8 KND97546.1 - 0.072 13.0 0.1 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 ERp29, N-terminal domain DUF836 PF05768.9 KND97547.1 - 3.7e-14 52.7 0.8 4.8e-14 52.3 0.5 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 KND97547.1 - 0.0071 16.3 0.4 0.013 15.4 0.3 1.5 1 0 0 1 1 1 1 Glutaredoxin adh_short PF00106.20 KND97548.1 - 1.6e-26 93.2 0.0 2.1e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND97548.1 - 3.3e-09 36.8 0.0 4.3e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND97548.1 - 3.6e-08 33.2 0.0 6.1e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KND97548.1 - 6.1e-07 28.8 0.0 6.8e-06 25.4 0.0 2.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KND97548.1 - 1e-05 25.6 0.0 4.2e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KND97548.1 - 0.00072 19.0 0.0 0.0014 18.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KND97548.1 - 0.0027 17.4 0.1 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 KND97548.1 - 0.047 12.9 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DUF676 PF05057.9 KND97549.1 - 9.6e-41 139.4 0.0 1.6e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 KND97549.1 - 0.0016 18.2 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 KND97549.1 - 0.016 14.2 0.2 0.027 13.4 0.2 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Transket_pyr PF02779.19 KND97550.1 - 1.2e-64 217.0 0.0 2.6e-64 215.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KND97550.1 - 3.3e-54 183.6 0.0 5.1e-54 183.0 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Pam17 PF08566.5 KND97551.1 - 2.6e-65 219.3 0.0 3.2e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 BPD_transp_2 PF02653.11 KND97551.1 - 0.00062 18.8 0.1 0.00079 18.4 0.1 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component SNF2_N PF00176.18 KND97552.1 - 5.1e-82 275.0 1.3 5.1e-82 275.0 0.9 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 KND97552.1 - 1.1e-20 73.2 0.4 4.9e-20 71.2 0.2 2.2 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 KND97552.1 - 6.1e-19 67.6 0.0 4.5e-17 61.6 0.0 3.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SnAC PF14619.1 KND97552.1 - 7.4e-14 51.6 1.9 7.4e-14 51.6 1.3 3.6 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex DEAD PF00270.24 KND97552.1 - 1.6e-06 27.6 1.2 1e-05 25.1 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase HSA PF07529.8 KND97552.1 - 0.00028 20.5 1.4 0.00028 20.5 1.0 3.1 2 0 0 2 2 2 1 HSA peroxidase PF00141.18 KND97553.1 - 9.3e-41 139.8 0.0 2e-40 138.6 0.0 1.6 2 0 0 2 2 2 1 Peroxidase Ribosomal_L6 PF00347.18 KND97554.1 - 3.1e-29 101.2 5.3 1.7e-15 57.2 0.6 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Thermopsin PF05317.6 KND97554.1 - 0.068 12.0 0.3 0.094 11.6 0.2 1.1 1 0 0 1 1 1 0 Thermopsin PDT PF00800.13 KND97555.1 - 5e-05 22.9 0.0 8.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 KND97555.1 - 0.0064 15.9 0.0 0.19 11.2 0.0 2.2 2 0 0 2 2 2 1 ACT domain zf-rbx1 PF12678.2 KND97556.1 - 1.6e-31 108.1 13.1 2.1e-31 107.8 9.1 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KND97556.1 - 1.1e-15 57.2 10.2 1.5e-15 56.8 7.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KND97556.1 - 1.2e-05 25.0 12.4 6e-05 22.7 8.6 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KND97556.1 - 0.0097 15.5 11.5 0.098 12.3 8.0 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 KND97556.1 - 0.079 12.4 2.8 0.14 11.6 1.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.1 KND97556.1 - 0.098 12.6 11.3 5.8 7.0 7.8 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KND97556.1 - 1.1 9.1 7.7 3.1 7.7 0.3 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KND97556.1 - 1.1 8.9 11.7 33 4.2 8.1 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND97556.1 - 1.6 8.4 10.4 11 5.8 7.2 2.2 1 1 0 1 1 1 0 zinc-RING finger domain zf-HC5HC2H PF13771.1 KND97556.1 - 3.9 7.6 10.0 1.7e+02 2.4 6.6 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain FANCL_C PF11793.3 KND97556.1 - 5.4 7.0 10.2 42 4.2 7.2 2.2 1 1 1 2 2 2 0 FANCL C-terminal domain Med7 PF05983.6 KND97557.1 - 1.3e-62 210.3 2.5 1.5e-62 210.1 1.7 1.0 1 0 0 1 1 1 1 MED7 protein Adaptin_N PF01602.15 KND97558.1 - 6.6e-125 417.4 11.8 9.3e-125 416.9 8.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KND97558.1 - 1.9e-21 76.6 3.3 2.8e-21 76.1 0.3 2.6 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KND97558.1 - 5.4e-14 52.2 0.3 2e-06 27.9 0.0 4.2 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 KND97558.1 - 5.5e-09 35.3 1.6 0.12 12.5 0.0 4.7 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 KND97558.1 - 0.00077 19.8 1.1 1 9.9 0.0 4.2 3 1 1 4 4 4 1 HEAT-like repeat Atx10homo_assoc PF09759.4 KND97558.1 - 0.0075 15.9 0.1 3.1 7.5 0.0 2.9 2 1 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain DUF2989 PF11207.3 KND97558.1 - 0.014 14.8 0.7 0.23 10.9 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2989) Guanylate_kin PF00625.16 KND97558.1 - 0.046 13.1 0.2 0.1 12.0 0.1 1.5 1 0 0 1 1 1 0 Guanylate kinase Arm PF00514.18 KND97558.1 - 0.06 13.1 0.0 1.5 8.7 0.0 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Mog1 PF04603.7 KND97559.1 - 3.6e-19 69.1 0.1 4.7e-14 52.5 0.0 2.1 2 0 0 2 2 2 2 Ran-interacting Mog1 protein Gly_transf_sug PF04488.10 KND97561.1 - 1.2e-13 51.3 0.0 3.9e-13 49.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif NVEALA PF14055.1 KND97561.1 - 0.092 12.4 0.2 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 NVEALA protein DnaG_DnaB_bind PF08278.6 KND97561.1 - 0.14 12.3 4.3 0.48 10.6 1.5 2.5 3 0 0 3 3 3 0 DNA primase DnaG DnaB-binding Saccharop_dh PF03435.13 KND97562.1 - 3.8e-131 437.6 0.0 8.4e-131 436.4 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KND97562.1 - 6.6e-07 29.4 0.2 1.5e-06 28.3 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KND97562.1 - 1.5e-05 25.0 0.1 2.7e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KND97562.1 - 0.0014 18.9 0.6 0.0026 18.0 0.2 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KND97562.1 - 0.0023 17.8 0.2 0.0058 16.5 0.1 1.6 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 KND97562.1 - 0.0043 17.0 0.3 0.0082 16.1 0.2 1.5 1 0 0 1 1 1 1 TrkA-N domain NmrA PF05368.8 KND97562.1 - 0.024 13.8 0.2 0.048 12.8 0.1 1.5 1 1 0 1 1 1 0 NmrA-like family GFO_IDH_MocA PF01408.17 KND97562.1 - 0.025 15.0 0.4 0.08 13.4 0.2 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DUF2325 PF10087.4 KND97562.1 - 0.047 13.5 0.2 0.091 12.6 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) NAD_binding_3 PF03447.11 KND97562.1 - 0.14 12.5 0.2 0.28 11.5 0.2 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Tubulin_3 PF14881.1 KND97563.1 - 1.2e-25 90.0 0.2 2.3e-25 89.0 0.2 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 KND97563.1 - 4.9e-13 49.1 0.2 8.3e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 KND97563.1 - 0.00044 20.1 0.0 0.0018 18.1 0.0 1.8 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain LIP PF03583.9 KND97564.1 - 2e-91 306.1 0.0 2.6e-91 305.8 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 KND97564.1 - 2.2e-05 24.2 0.0 4.7e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KND97564.1 - 0.0018 17.5 0.0 0.38 9.9 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family DnaJ PF00226.26 KND97568.1 - 2.2e-25 88.1 1.8 3.4e-25 87.5 1.3 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KND97568.1 - 8.6e-15 54.4 0.0 1e-11 44.5 0.0 3.2 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KND97568.1 - 9.9e-14 51.1 22.0 2.1e-13 50.1 15.2 1.6 1 0 0 1 1 1 1 DnaJ central domain RPT PF13446.1 KND97568.1 - 0.0065 15.8 0.0 0.018 14.4 0.0 1.7 2 0 0 2 2 2 1 A repeated domain in UCH-protein DZR PF12773.2 KND97568.1 - 0.17 11.7 10.2 1.5 8.6 0.8 2.3 2 0 0 2 2 2 0 Double zinc ribbon HypA PF01155.14 KND97568.1 - 8.2 6.1 12.6 1.9 8.2 1.4 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family PIG-X PF08320.7 KND97569.1 - 1.4e-47 161.6 0.0 2.2e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 DUF2526 PF10735.4 KND97569.1 - 0.078 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) PEMT PF04191.8 KND97570.1 - 5.6e-33 113.2 3.2 1.1e-32 112.2 2.2 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF4118 PF13493.1 KND97570.1 - 5.6 7.2 9.0 1.6 8.9 0.7 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4118) Vac_ImportDeg PF09783.4 KND97571.1 - 3.5e-53 179.7 0.1 5.4e-53 179.0 0.1 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein DUF3929 PF13066.1 KND97572.1 - 0.12 12.1 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3929) UDG PF03167.14 KND97576.1 - 9.1e-11 41.4 0.0 1.2e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Brr6_like_C_C PF10104.4 KND97577.1 - 8.6e-46 154.8 0.4 1.3e-45 154.1 0.3 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF624 PF04854.9 KND97577.1 - 0.018 14.8 0.3 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF624 Pex24p PF06398.6 KND97577.1 - 0.044 12.5 0.1 2.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF4446 PF14584.1 KND97577.1 - 0.16 11.8 3.2 0.2 11.4 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) SNF PF00209.13 KND97577.1 - 2.4 6.5 4.6 1.1 7.6 1.6 1.5 1 1 0 2 2 2 0 Sodium:neurotransmitter symporter family Fungal_trans_2 PF11951.3 KND97579.1 - 1.3e-09 37.1 0.8 1e-08 34.2 0.2 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND97579.1 - 1.2e-07 31.4 7.4 2.3e-07 30.6 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mg_trans_NIPA PF05653.9 KND97579.1 - 0.083 11.8 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Magnesium transporter NIPA ABC_membrane PF00664.18 KND97580.1 - 1e-31 110.3 17.6 1.3e-31 110.0 12.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KND97580.1 - 1e-08 35.5 0.0 2.1e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 KND97580.1 - 2.1e-06 27.0 0.0 5.3e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 KND97580.1 - 0.00049 20.4 0.0 0.00089 19.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KND97580.1 - 0.00066 18.4 0.0 0.00096 17.9 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_29 PF13555.1 KND97580.1 - 0.0007 19.0 0.0 0.0022 17.5 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KND97580.1 - 0.0023 17.9 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KND97580.1 - 0.0023 18.7 0.0 0.0052 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 KND97580.1 - 0.02 14.8 0.3 0.032 14.1 0.2 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KND97580.1 - 0.026 14.2 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 KND97580.1 - 0.036 13.9 0.0 0.082 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KND97580.1 - 0.042 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KND97580.1 - 0.058 12.8 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_5 PF07728.9 KND97580.1 - 0.069 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 KND97580.1 - 0.098 12.9 0.0 0.62 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KND97580.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.17 KND97580.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_15 PF13175.1 KND97580.1 - 0.18 10.8 0.0 0.27 10.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain ABC_membrane PF00664.18 KND97581.1 - 2.3e-34 119.0 15.6 3.4e-34 118.4 10.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KND97581.1 - 1.6e-31 109.4 0.0 5.1e-27 94.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KND97581.1 - 3.1e-09 37.2 0.1 0.00041 20.3 0.0 3.5 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 KND97581.1 - 2.6e-08 33.3 1.8 0.0091 15.2 0.0 3.3 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KND97581.1 - 0.00033 21.4 0.1 0.0012 19.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KND97581.1 - 0.0061 16.0 0.1 0.014 14.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 KND97581.1 - 0.0092 15.8 0.0 5.1 7.0 0.0 2.6 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 KND97581.1 - 0.012 14.9 0.0 0.086 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KND97581.1 - 0.019 14.4 1.5 3.3 7.0 0.1 3.1 3 0 0 3 3 3 0 AAA-like domain AAA_18 PF13238.1 KND97581.1 - 0.039 14.2 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KND97581.1 - 0.086 12.9 3.4 6.5 6.9 0.2 3.2 3 0 0 3 3 3 0 AAA domain ThiF PF00899.16 KND97582.1 - 9.8e-51 171.1 0.3 7.8e-32 109.9 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 KND97582.1 - 7.1e-47 158.6 0.0 1.6e-46 157.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 KND97582.1 - 5.6e-38 128.3 1.2 2.1e-24 84.8 0.4 2.5 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KND97582.1 - 2.3e-26 90.8 0.8 7.3e-21 73.2 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site 2-Hacid_dh_C PF02826.14 KND97582.1 - 0.18 10.9 0.1 15 4.6 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thioredoxin PF00085.15 KND97583.1 - 6.2e-15 54.7 0.6 5.4e-11 42.1 0.0 3.6 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 KND97583.1 - 4.7e-07 29.8 2.0 6.5e-06 26.0 1.2 2.9 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KND97583.1 - 0.027 14.5 1.6 0.18 11.9 0.1 2.7 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_4 PF13462.1 KND97583.1 - 0.11 12.4 3.0 0.23 11.4 0.2 2.3 2 0 0 2 2 2 0 Thioredoxin Hexapep PF00132.19 KND97584.1 - 3.5e-11 42.0 14.6 0.00029 20.2 0.5 4.8 4 2 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KND97584.1 - 1.3e-05 24.6 10.3 0.022 14.3 0.2 3.7 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase BDV_P40 PF06407.6 KND97584.1 - 0.044 12.6 0.2 0.093 11.5 0.1 1.6 1 1 1 2 2 2 0 Borna disease virus P40 protein PMI_typeI PF01238.16 KND97585.1 - 1.4e-152 508.0 0.0 1.6e-152 507.8 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 KND97585.1 - 0.018 14.7 0.0 0.21 11.2 0.0 2.3 2 0 0 2 2 2 0 AraC-like ligand binding domain Cupin_2 PF07883.6 KND97585.1 - 0.08 12.4 0.1 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Cupin domain RRM_1 PF00076.17 KND97586.1 - 6.3e-15 54.5 0.0 9.6e-15 53.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND97586.1 - 7.2e-11 41.9 0.0 1.3e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND97586.1 - 6.5e-08 32.3 0.0 9.3e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 KND97586.1 - 0.00017 20.2 4.1 0.00022 19.8 2.8 1.2 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) GRP PF07172.6 KND97586.1 - 0.37 11.2 14.2 0.17 12.3 7.4 1.9 2 0 0 2 2 2 0 Glycine rich protein family Nop16 PF09420.5 KND97587.1 - 1.5e-43 148.7 11.6 1.8e-43 148.4 8.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Integrin_b_cyt PF08725.6 KND97587.1 - 0.0065 15.8 0.2 0.0065 15.8 0.1 2.3 3 0 0 3 3 3 1 Integrin beta cytoplasmic domain CAP_assoc_N PF14504.1 KND97587.1 - 0.016 14.9 0.3 0.034 13.8 0.2 1.5 1 0 0 1 1 1 0 CAP-associated N-terminal KTI12 PF08433.5 KND97587.1 - 0.032 13.4 1.4 0.06 12.5 0.5 1.7 1 1 1 2 2 2 0 Chromatin associated protein KTI12 ParA PF10609.4 KND97588.1 - 3.3e-37 126.2 0.0 7.5e-37 125.0 0.0 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KND97588.1 - 1.1e-18 67.3 0.0 1.7e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 KND97588.1 - 7.6e-08 31.7 0.0 1.3e-06 27.7 0.0 2.3 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 KND97588.1 - 2.9e-06 26.5 0.7 1.7e-05 24.0 0.2 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 KND97588.1 - 4.8e-06 26.5 0.0 1.6e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain YhjQ PF06564.7 KND97588.1 - 0.00014 21.3 0.0 0.00022 20.6 0.0 1.3 1 1 0 1 1 1 1 YhjQ protein AAA_25 PF13481.1 KND97588.1 - 0.0011 18.4 0.1 0.002 17.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 KND97588.1 - 0.0028 16.4 0.2 0.0047 15.7 0.2 1.3 1 0 0 1 1 1 1 ArgK protein Fer4_NifH PF00142.13 KND97588.1 - 0.013 14.6 0.1 0.027 13.6 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_19 PF13245.1 KND97588.1 - 0.019 14.6 0.4 1.2 8.8 0.0 2.4 2 1 0 2 2 2 0 Part of AAA domain AAA_26 PF13500.1 KND97588.1 - 0.024 14.2 0.1 6.4 6.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 KND97588.1 - 0.027 14.1 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Zeta_toxin PF06414.7 KND97588.1 - 0.089 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF258 PF03193.11 KND97588.1 - 0.11 11.6 0.3 0.23 10.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 KND97588.1 - 0.16 11.3 0.1 0.27 10.6 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain SNARE PF05739.14 KND97589.1 - 0.00076 19.1 1.9 0.0011 18.6 1.3 1.2 1 0 0 1 1 1 1 SNARE domain AIP3 PF03915.8 KND97589.1 - 0.013 14.4 1.3 0.015 14.2 0.9 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 Syntaxin_2 PF14523.1 KND97589.1 - 0.049 13.6 0.8 3.3 7.8 0.2 2.0 2 0 0 2 2 2 0 Syntaxin-like protein VHS PF00790.14 KND97591.1 - 4.1e-09 36.1 0.0 8.8e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 KND97591.1 - 3e-05 23.8 0.0 6.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 GAT domain GTP_EFTU PF00009.22 KND97593.1 - 4.1e-46 156.7 0.0 7.8e-46 155.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KND97593.1 - 1.3e-24 86.2 1.8 1.5e-24 86.0 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KND97593.1 - 2.6e-07 30.6 0.2 6e-07 29.4 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KND97593.1 - 0.0003 20.7 0.0 0.001 19.0 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ndc1_Nup PF09531.5 KND97593.1 - 1.6 7.0 4.7 2 6.7 3.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup IPK PF03770.11 KND97594.1 - 9e-52 175.5 0.0 1.1e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase SNARE PF05739.14 KND97597.1 - 1.4e-13 50.2 3.7 1.4e-13 50.2 2.6 2.5 2 1 1 3 3 3 1 SNARE domain DUF3753 PF12575.3 KND97597.1 - 0.013 15.3 6.3 0.39 10.5 0.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) Syntaxin PF00804.20 KND97597.1 - 0.021 14.9 25.6 1.6e+02 2.4 17.7 2.9 1 1 0 1 1 1 0 Syntaxin DUF805 PF05656.9 KND97597.1 - 0.046 13.5 0.5 0.069 12.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DUF4094 PF13334.1 KND97597.1 - 0.14 12.5 0.4 0.14 12.5 0.3 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF4094) T2SF PF00482.18 KND97597.1 - 0.45 10.4 5.6 0.37 10.7 0.1 2.8 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F DUF2203 PF09969.4 KND97597.1 - 2.9 8.1 12.0 0.17 12.0 0.7 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) ISG65-75 PF11727.3 KND97597.1 - 9 5.2 11.2 0.91 8.5 2.1 2.4 1 1 2 3 3 3 0 Invariant surface glycoprotein Internalin_N PF12354.3 KND97597.1 - 9.1 5.9 8.1 0.99 9.0 1.2 2.6 3 0 0 3 3 3 0 Bacterial adhesion/invasion protein N terminal EMP24_GP25L PF01105.19 KND97597.1 - 9.4 5.9 12.4 2.5 7.7 0.6 3.4 1 1 3 4 4 4 0 emp24/gp25L/p24 family/GOLD Transp_cyt_pur PF02133.10 KND97598.1 - 9.7e-61 205.6 42.1 1.3e-60 205.2 29.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin HEAT PF02985.17 KND97599.1 - 0.0026 17.6 1.3 10 6.4 0.0 5.5 9 0 0 9 9 9 2 HEAT repeat RTBV_P46 PF06216.6 KND97599.1 - 3 6.5 6.7 0.25 10.1 0.7 1.8 2 0 0 2 2 2 0 Rice tungro bacilliform virus P46 protein ETF PF01012.16 KND97600.1 - 2.4e-34 118.4 0.2 3.1e-34 118.0 0.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain KAP_NTPase PF07693.9 KND97601.1 - 7e-06 25.2 0.0 7.4e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain AAA_17 PF13207.1 KND97601.1 - 7.5e-05 23.5 0.0 0.00017 22.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 KND97601.1 - 0.00016 21.2 0.0 0.0004 19.9 0.0 1.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 KND97601.1 - 0.00035 20.6 0.0 0.00084 19.3 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 KND97601.1 - 0.0018 18.3 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Torsin PF06309.6 KND97601.1 - 0.0029 17.4 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 Torsin cobW PF02492.14 KND97601.1 - 0.0068 15.8 0.0 0.011 15.2 0.0 1.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 KND97601.1 - 0.01 14.9 0.0 0.057 12.5 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin Adeno_IVa2 PF02456.10 KND97601.1 - 0.013 14.1 0.0 0.021 13.4 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein T2SE PF00437.15 KND97601.1 - 0.017 14.0 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 KND97601.1 - 0.018 14.7 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.1 KND97601.1 - 0.022 14.6 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KND97601.1 - 0.022 14.8 0.0 0.044 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KND97601.1 - 0.031 14.5 0.0 0.052 13.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ArgK PF03308.11 KND97601.1 - 0.036 12.8 0.0 0.057 12.1 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Virul_Fac PF10139.4 KND97601.1 - 0.042 11.7 0.0 0.062 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative bacterial virulence factor RNA12 PF10443.4 KND97601.1 - 0.046 12.2 0.0 0.068 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA12 protein Arch_ATPase PF01637.13 KND97601.1 - 0.058 13.0 0.0 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase AAA_19 PF13245.1 KND97601.1 - 0.066 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 KND97601.1 - 0.067 13.1 0.8 2.1 8.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KND97601.1 - 0.068 13.0 0.0 0.17 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 KND97601.1 - 0.09 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 KND97601.1 - 0.096 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 KND97601.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.10 KND97601.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 NTPase Proteasome PF00227.21 KND97602.1 - 2e-47 160.9 0.2 2.3e-47 160.7 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Pox_A51 PF04948.8 KND97602.1 - 0.1 11.2 0.4 0.15 10.6 0.3 1.2 1 0 0 1 1 1 0 Poxvirus A51 protein DUF3848 PF12959.2 KND97603.1 - 0.079 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) Oxidored_FMN PF00724.15 KND97605.1 - 4e-107 358.1 0.0 4.6e-107 357.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pro_isomerase PF00160.16 KND97607.1 - 2.5e-38 131.7 0.2 3.4e-38 131.2 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 KND97608.1 - 2e-15 56.1 0.1 4.5e-15 55.0 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND97608.1 - 3.9e-11 42.7 0.1 1e-10 41.4 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND97608.1 - 4.9e-08 32.7 0.0 7.6e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribophorin_I PF04597.9 KND97609.1 - 1.2e-117 393.0 1.6 1.4e-117 392.8 1.1 1.0 1 0 0 1 1 1 1 Ribophorin I Peptidase_A22B PF04258.8 KND97612.1 - 2.7e-50 171.5 9.3 4.6e-50 170.7 6.4 1.4 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 KND97612.1 - 7e-08 31.9 2.6 7e-08 31.9 1.8 2.5 3 1 0 3 3 3 1 Protein of unknown function (DUF1119) Oxidored_FMN PF00724.15 KND97613.1 - 3.8e-96 322.0 0.0 4.4e-96 321.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dynamin_M PF01031.15 KND97615.1 - 9e-109 362.8 0.0 1.6e-108 362.0 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 KND97615.1 - 7.2e-48 162.5 0.0 2.2e-47 160.9 0.0 1.9 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KND97615.1 - 1.2e-28 98.7 4.6 3.3e-28 97.4 3.2 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain Saw1 PF11561.3 KND97616.1 - 7.1e-26 90.9 1.2 9.4e-26 90.5 0.9 1.2 1 0 0 1 1 1 1 Single strand annealing-weakened 1 GIT_SHD PF08518.6 KND97616.1 - 0.079 12.3 1.1 0.48 9.8 0.1 2.4 2 0 0 2 2 2 0 Spa2 homology domain (SHD) of GIT DUF2746 PF10874.3 KND97618.1 - 0.13 12.4 0.5 0.17 12.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) MoeA_C PF03454.10 KND97622.1 - 0.12 12.3 0.0 39 4.2 0.0 3.5 3 1 1 4 4 4 0 MoeA C-terminal region (domain IV) DIOX_N PF14226.1 KND97624.1 - 1.2e-16 61.3 0.1 2.3e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KND97624.1 - 3.4e-15 56.1 0.0 6.2e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ketoacyl-synt PF00109.21 KND97626.1 - 7.7e-20 71.4 0.1 1.6e-19 70.4 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 KND97626.1 - 1.1e-19 71.2 0.0 5.5e-19 68.8 0.0 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ACPS PF01648.15 KND97626.1 - 1.5e-18 66.7 0.1 3.4e-18 65.5 0.1 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 KND97626.1 - 2.4e-12 46.7 0.0 6.6e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KND97626.1 - 4.4e-07 29.9 0.0 3.7e-06 26.9 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KND97626.1 - 0.0025 17.5 0.7 0.0091 15.6 0.0 2.3 2 0 0 2 2 2 1 KR domain Sec7 PF01369.15 KND97628.1 - 8.2e-66 221.3 0.6 1.3e-64 217.3 0.0 3.0 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 KND97628.1 - 1.4e-54 184.0 5.5 1.4e-54 184.0 3.8 3.8 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KND97628.1 - 2.2e-31 107.1 2.4 9.3e-30 101.9 0.4 4.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) Stb3 PF10330.4 KND97630.1 - 3.8e-30 103.4 0.0 7.4e-30 102.4 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein MCM PF00493.18 KND97631.1 - 1.5e-132 441.4 0.0 2.5e-132 440.7 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KND97631.1 - 2.4e-25 89.3 3.9 3.3e-25 88.9 0.5 2.7 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 KND97631.1 - 3.4e-08 32.8 0.1 2.2e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KND97631.1 - 4e-06 26.5 0.0 1.8e-05 24.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 KND97631.1 - 0.039 14.3 0.6 0.14 12.5 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KND97631.1 - 0.041 13.4 0.0 0.13 11.9 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KND97631.1 - 0.072 12.5 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain zf-UDP PF14569.1 KND97631.1 - 0.091 12.5 0.6 0.2 11.4 0.4 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger NAGidase PF07555.8 KND97631.1 - 0.13 11.1 0.1 0.26 10.1 0.1 1.4 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase DUF202 PF02656.10 KND97632.1 - 1.3e-16 60.5 1.8 1.3e-16 60.5 1.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PRA1 PF03208.14 KND97632.1 - 0.66 9.3 5.1 0.1 11.9 1.0 1.5 2 0 0 2 2 2 0 PRA1 family protein SAP PF02037.22 KND97633.1 - 5.3e-12 44.9 0.7 1.1e-11 43.9 0.5 1.6 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 KND97633.1 - 0.00014 21.2 0.5 0.00047 19.6 0.3 1.8 1 1 0 1 1 1 1 HeH/LEM domain DUF572 PF04502.8 KND97633.1 - 0.052 12.7 7.7 0.066 12.4 5.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2201_N PF13203.1 KND97633.1 - 0.75 8.9 5.2 0.96 8.5 3.6 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF2052 PF09747.4 KND97633.1 - 0.93 9.3 8.5 1.2 9.0 5.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) ParB PF08775.5 KND97633.1 - 1.2 9.4 6.5 4.1 7.7 2.0 2.2 1 1 1 2 2 2 0 ParB family Borrelia_P83 PF05262.6 KND97633.1 - 2.2 6.4 14.1 2.5 6.2 9.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Usp PF00582.21 KND97633.1 - 2.7 8.1 9.3 1.5 9.0 5.0 1.7 1 1 1 2 2 2 0 Universal stress protein family GAGA_bind PF06217.7 KND97633.1 - 4.7 7.0 6.8 6.1 6.7 4.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family TauD PF02668.11 KND97634.1 - 1.7e-52 178.6 0.6 2.6e-52 178.0 0.4 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Peptidase_M1 PF01433.15 KND97635.1 - 3.2e-131 438.0 1.9 4.6e-131 437.5 1.3 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KND97635.1 - 8.3e-47 160.0 2.3 1.1e-46 159.5 1.6 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KND97635.1 - 2.7e-18 66.2 0.4 6.4e-18 65.0 0.3 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily Asn_synthase PF00733.16 KND97636.1 - 1.2e-64 218.2 0.0 1.6e-64 217.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase DUF347 PF03988.7 KND97637.1 - 0.067 13.0 0.8 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) SAC3_GANP PF03399.11 KND97638.1 - 6e-29 101.0 2.0 8.7e-29 100.5 1.4 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KND97638.1 - 4.1e-14 52.5 1.2 4.1e-14 52.5 0.9 1.8 3 0 0 3 3 3 1 COP9 signalosome, subunit CSN8 VPS28 PF03997.7 KND97639.1 - 1.7e-39 135.3 1.0 8.1e-39 133.1 0.7 1.9 1 1 0 1 1 1 1 VPS28 protein Gag_p30 PF02093.11 KND97639.1 - 0.026 13.7 0.0 0.064 12.4 0.0 1.7 1 1 1 2 2 2 0 Gag P30 core shell protein Arrestin_C PF02752.17 KND97640.1 - 0.00024 21.2 0.0 0.00056 20.0 0.0 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain GlcNAc PF11397.3 KND97640.1 - 0.028 13.5 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) Steroid_dh PF02544.11 KND97641.1 - 7.1e-11 42.0 15.4 7.1e-11 42.0 10.7 2.4 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase MFS_1 PF07690.11 KND97642.1 - 2.2e-08 33.2 39.2 2.7e-05 23.0 10.3 3.2 2 1 0 2 2 2 2 Major Facilitator Superfamily Transp_cyt_pur PF02133.10 KND97643.1 - 5.1e-65 219.7 41.1 6.5e-65 219.4 28.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NADH_u_ox_C PF12853.2 KND97644.1 - 1.1e-42 143.6 1.1 1.5e-42 143.1 0.7 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.4 KND97644.1 - 4e-31 107.0 0.3 5.6e-31 106.6 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Mpv17_PMP22 PF04117.7 KND97647.1 - 1e-22 79.4 3.7 2.3e-22 78.3 1.8 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family POC1 PF10450.4 KND97648.1 - 1.1e-07 30.9 0.0 1.3e-07 30.6 0.0 1.2 1 1 0 1 1 1 1 POC1 chaperone COQ9 PF08511.6 KND97650.1 - 2.7e-23 81.2 0.2 4e-23 80.7 0.2 1.3 1 0 0 1 1 1 1 COQ9 Prefoldin_2 PF01920.15 KND97651.1 - 5e-23 80.8 12.1 6.3e-23 80.5 8.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit IncA PF04156.9 KND97651.1 - 0.0006 19.4 11.5 0.00072 19.1 8.0 1.1 1 0 0 1 1 1 1 IncA protein DUF1192 PF06698.6 KND97651.1 - 0.045 13.5 0.5 0.045 13.5 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Herpes_UL14 PF03580.9 KND97651.1 - 0.055 13.2 0.3 0.055 13.2 0.2 2.0 2 0 0 2 2 2 0 Herpesvirus UL14-like protein MAAL_C PF07476.6 KND97651.1 - 0.084 11.7 0.6 0.11 11.3 0.1 1.4 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus Tropomyosin_1 PF12718.2 KND97651.1 - 0.17 11.6 12.2 0.36 10.6 8.5 1.6 1 1 0 1 1 1 0 Tropomyosin like Atg14 PF10186.4 KND97651.1 - 0.3 9.9 7.5 0.61 8.9 5.2 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PspA_IM30 PF04012.7 KND97651.1 - 0.52 9.6 14.0 0.78 9.0 7.9 1.8 1 1 1 2 2 2 0 PspA/IM30 family UPF0270 PF06794.7 KND97651.1 - 0.55 10.0 4.1 0.28 10.9 0.4 2.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0270) Fib_alpha PF08702.5 KND97651.1 - 0.74 9.9 7.5 0.72 9.9 0.9 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.4 KND97651.1 - 0.89 9.4 13.9 0.54 10.1 1.9 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Snapin_Pallidin PF14712.1 KND97651.1 - 0.96 9.8 11.6 1.7 8.9 5.0 2.3 1 1 1 2 2 2 0 Snapin/Pallidin DUF4164 PF13747.1 KND97651.1 - 1.1 9.4 7.7 0.43 10.7 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Cauli_AT PF03233.8 KND97651.1 - 1.1 8.9 5.6 6.7 6.3 0.3 2.1 2 0 0 2 2 2 0 Aphid transmission protein Prefoldin PF02996.12 KND97651.1 - 1.2 8.7 10.4 1.6 8.3 0.5 2.3 2 0 0 2 2 2 0 Prefoldin subunit TPR_MLP1_2 PF07926.7 KND97651.1 - 1.3 8.8 13.3 2.1 8.1 2.3 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 KND97651.1 - 1.6 8.5 6.2 2.4 7.9 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc24 PF08286.6 KND97651.1 - 4 7.1 12.8 1.9 8.2 2.1 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Spc7 PF08317.6 KND97651.1 - 7.2 5.1 12.6 19 3.7 8.7 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.10 KND97651.1 - 7.8 6.0 11.3 0.96 8.9 1.3 2.4 2 1 0 2 2 2 0 Septum formation initiator FlaC_arch PF05377.6 KND97651.1 - 9.9 6.1 8.5 4.5 7.2 0.5 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) TFIIA PF03153.8 KND97652.1 - 0.12 12.2 9.9 0.18 11.6 6.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 KND97652.1 - 0.41 8.5 14.9 0.49 8.2 10.3 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KND97652.1 - 0.44 8.9 15.0 0.47 8.8 10.4 1.1 1 0 0 1 1 1 0 Daxx Family EBV-NA3 PF05009.7 KND97652.1 - 8.9 5.4 6.6 15 4.7 4.6 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) PRELI PF04707.9 KND97653.1 - 1.7e-33 115.4 0.1 2e-33 115.2 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family AA_permease PF00324.16 KND97654.1 - 2.1e-117 392.3 30.4 2.4e-117 392.1 21.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND97654.1 - 1.5e-35 122.6 36.2 1.7e-35 122.3 25.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF21 PF01595.15 KND97655.1 - 3.2e-33 114.5 0.1 4.9e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KND97655.1 - 0.012 15.3 0.0 0.46 10.3 0.0 2.6 2 0 0 2 2 2 0 CBS domain UPF0239 PF06783.6 KND97655.1 - 1.1 9.2 3.1 1.2 9.0 0.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) Pkinase PF00069.20 KND97657.1 - 2e-57 194.3 0.0 2.9e-57 193.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND97657.1 - 2.9e-23 82.2 0.0 4.1e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND97657.1 - 9.2e-06 24.8 0.0 0.00048 19.1 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KND97657.1 - 0.036 13.7 0.1 0.072 12.8 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KND97657.1 - 0.057 12.4 0.1 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1448 PF07289.6 KND97657.1 - 0.09 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1448) Solute_trans_a PF03619.11 KND97659.1 - 1.1e-84 284.0 3.6 1.4e-84 283.6 2.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha mIF3 PF14877.1 KND97660.1 - 1.2e-51 174.7 1.1 1.2e-51 174.7 0.7 1.9 2 0 0 2 2 2 1 Mitochondrial translation initiation factor Pal1 PF08316.6 KND97660.1 - 0.086 13.2 0.3 0.086 13.2 0.2 2.8 3 0 0 3 3 3 0 Pal1 cell morphology protein Fungal_trans PF04082.13 KND97661.1 - 1e-32 113.0 4.4 1e-32 113.0 3.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain GTP_cyclohydro2 PF00925.15 KND97664.1 - 4.5e-54 182.2 0.1 1.5e-48 164.2 0.0 2.1 1 1 0 2 2 2 2 GTP cyclohydrolase II Fer4 PF00037.22 KND97667.1 - 1.9e-14 52.5 15.4 3.1e-08 32.8 2.8 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 KND97667.1 - 4.1e-12 46.2 10.1 7.6e-12 45.4 7.0 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 KND97667.1 - 2.6e-11 43.5 21.3 3.3e-09 36.8 8.0 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 KND97667.1 - 1.2e-10 40.9 23.5 1.5e-08 34.2 8.6 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 KND97667.1 - 1.2e-10 41.9 8.7 3.1e-05 24.6 0.8 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.1 KND97667.1 - 1.2e-09 38.0 4.1 4.3e-05 23.4 0.5 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 KND97667.1 - 2.2e-08 33.8 32.0 3e-05 23.7 8.6 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 KND97667.1 - 5.3e-08 32.3 13.8 0.00039 20.1 1.5 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 KND97667.1 - 4.6e-07 29.6 13.1 0.00069 19.7 2.3 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 KND97667.1 - 5.2e-07 29.2 17.4 0.0012 18.6 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 KND97667.1 - 1.3e-05 25.4 12.0 0.00079 19.7 8.1 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 KND97667.1 - 3.1e-05 24.3 9.7 0.016 15.6 0.6 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 KND97667.1 - 0.0028 18.1 12.2 0.17 12.4 0.9 2.8 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.1 KND97667.1 - 0.0078 16.5 15.7 0.29 11.5 3.2 2.8 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 KND97667.1 - 0.014 15.9 17.5 0.039 14.5 2.8 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 KND97667.1 - 0.45 10.6 6.0 1.5 9.0 0.1 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain ABC2_membrane PF01061.19 KND97668.1 - 4.9e-91 303.5 41.3 6e-46 156.2 10.6 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 KND97668.1 - 1.3e-38 132.4 0.0 4.5e-19 69.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KND97668.1 - 4.9e-36 122.5 0.3 6.7e-32 109.2 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KND97668.1 - 1.4e-22 79.5 0.1 3.2e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 KND97668.1 - 1.1e-10 41.1 18.9 1.7e-06 27.3 2.6 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 KND97668.1 - 1.3e-08 34.5 0.1 0.00042 19.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KND97668.1 - 1.4e-07 30.8 0.1 2.7e-05 23.4 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KND97668.1 - 0.00017 21.6 1.4 0.00049 20.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KND97668.1 - 0.00024 21.2 0.0 0.11 12.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KND97668.1 - 0.00027 21.7 0.0 0.022 15.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KND97668.1 - 0.00036 20.4 0.1 0.32 10.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KND97668.1 - 0.00065 19.1 1.6 0.014 14.8 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 KND97668.1 - 0.00096 18.6 1.5 0.038 13.4 0.3 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 KND97668.1 - 0.0017 18.6 0.1 0.066 13.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 KND97668.1 - 0.0031 17.4 1.5 0.021 14.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KND97668.1 - 0.0032 17.0 0.2 0.19 11.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KND97668.1 - 0.0032 16.7 0.2 0.13 11.5 0.0 2.8 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 KND97668.1 - 0.006 16.2 1.5 0.58 9.8 0.1 2.9 3 0 0 3 3 3 1 NACHT domain UPF0079 PF02367.12 KND97668.1 - 0.007 15.9 0.8 0.12 11.9 0.1 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 KND97668.1 - 0.0074 16.2 0.1 0.93 9.4 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.1 KND97668.1 - 0.0099 15.8 0.2 0.33 10.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KND97668.1 - 0.015 15.0 1.2 0.41 10.4 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 KND97668.1 - 0.019 14.4 0.1 3.1 7.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 KND97668.1 - 0.056 13.6 0.0 2.2 8.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.10 KND97668.1 - 0.056 13.1 1.1 0.48 10.1 0.0 2.7 3 0 0 3 3 3 0 NTPase AAA_10 PF12846.2 KND97668.1 - 0.075 12.4 3.8 3.7 6.9 0.2 3.3 3 0 0 3 3 3 0 AAA-like domain Miro PF08477.8 KND97668.1 - 0.1 13.1 0.1 28 5.2 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein ABC_ATPase PF09818.4 KND97668.1 - 0.12 10.9 0.1 0.52 8.8 0.0 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_24 PF13479.1 KND97668.1 - 0.36 10.3 1.6 2.9 7.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KND97668.1 - 0.37 9.5 0.4 6.5 5.4 0.0 2.3 2 0 0 2 2 2 0 ArgK protein Glyco_hydro_47 PF01532.15 KND97670.1 - 1.6e-118 396.2 0.0 2.1e-118 395.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Aminotran_4 PF01063.14 KND97671.1 - 1.4e-32 113.0 0.0 1.6e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Mo25 PF08569.6 KND97672.1 - 2.8e-107 358.6 13.1 3.2e-107 358.4 9.1 1.0 1 0 0 1 1 1 1 Mo25-like RhoGEF PF00621.15 KND97672.1 - 0.093 12.6 5.8 0.22 11.3 3.7 1.9 1 1 0 1 1 1 0 RhoGEF domain Pkip-1 PF06878.6 KND97672.1 - 0.54 10.1 8.6 0.099 12.5 0.3 2.7 3 0 0 3 3 3 0 Pkip-1 protein EAP30 PF04157.11 KND97674.1 - 1.2e-34 119.4 0.0 2e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 KND97674.1 - 3.6e-23 81.1 0.1 1.2e-22 79.5 0.1 2.0 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 DZR PF12773.2 KND97674.1 - 0.0016 18.1 1.8 0.0016 18.1 1.3 2.2 2 1 0 2 2 2 1 Double zinc ribbon zf-ribbon_3 PF13248.1 KND97674.1 - 0.011 14.8 6.7 0.018 14.2 0.7 2.5 2 0 0 2 2 2 0 zinc-ribbon domain HTH_24 PF13412.1 KND97674.1 - 0.015 14.6 0.0 0.033 13.5 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding zf-RanBP PF00641.13 KND97674.1 - 0.15 11.1 12.4 0.039 13.0 0.9 3.3 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 KND97674.1 - 0.52 9.9 8.2 0.38 10.3 0.4 2.6 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DUF2054 PF10218.4 KND97674.1 - 3.3 7.5 8.8 0.11 12.2 1.2 2.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2054) SSF PF00474.12 KND97675.1 - 3.6e-19 68.7 26.6 6.5e-19 67.8 18.5 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Amidase PF01425.16 KND97676.1 - 1.1e-89 301.2 0.1 1.6e-89 300.8 0.1 1.2 1 0 0 1 1 1 1 Amidase AHS2 PF02626.10 KND97676.1 - 1.4e-85 286.8 0.0 2.3e-85 286.1 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 KND97676.1 - 7.5e-61 205.0 0.0 1.9e-60 203.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AHS1 PF02682.11 KND97676.1 - 3.6e-45 153.9 0.0 6.7e-45 153.0 0.0 1.4 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 CPSase_L_chain PF00289.17 KND97676.1 - 9.3e-40 135.1 0.1 2.5e-39 133.7 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KND97676.1 - 7.1e-32 109.5 0.0 1.7e-31 108.3 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 KND97676.1 - 6.1e-19 68.4 0.0 1.6e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KND97676.1 - 2.5e-17 62.2 2.9 9.3e-17 60.4 2.0 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 KND97676.1 - 4.5e-10 39.2 0.0 9.8e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KND97676.1 - 6.8e-06 25.5 0.0 1.7e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KND97676.1 - 0.00013 21.5 0.0 0.0027 17.2 0.0 2.3 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KND97676.1 - 0.00021 21.1 0.0 0.00053 19.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.1 KND97676.1 - 0.00057 19.5 0.3 0.0015 18.2 0.2 1.7 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain NQRA PF05896.6 KND97676.1 - 0.0054 15.9 0.3 0.01 15.0 0.2 1.3 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATP-grasp_5 PF13549.1 KND97676.1 - 0.011 14.9 0.0 0.03 13.5 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain HlyD PF00529.15 KND97676.1 - 0.062 12.6 0.1 5.8 6.1 0.0 2.2 2 0 0 2 2 2 0 HlyD family secretion protein Toxin_59 PF15537.1 KND97676.1 - 0.08 13.0 0.5 1.4 8.9 0.0 2.9 3 0 0 3 3 3 0 Putative toxin 59 Biotin_lipoyl_2 PF13533.1 KND97676.1 - 0.28 10.8 2.0 0.87 9.3 0.1 2.5 2 1 1 3 3 3 0 Biotin-lipoyl like Hat1_N PF10394.4 KND97677.1 - 2.3e-34 118.8 0.2 4e-34 118.0 0.1 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.19 KND97677.1 - 0.0064 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KND97677.1 - 0.055 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pil1 PF13805.1 KND97679.1 - 1.3e-153 509.8 0.8 1.6e-153 509.5 0.6 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 PCP_red PF08369.5 KND97679.1 - 0.26 11.1 4.9 8.2 6.3 0.1 3.5 3 0 0 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit Rad21_Rec8_N PF04825.8 KND97680.1 - 1.9e-16 59.9 0.0 3.1e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KND97680.1 - 0.0003 19.8 0.0 0.00073 18.6 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein FoP_duplication PF13865.1 KND97680.1 - 0.064 13.7 0.5 0.13 12.7 0.3 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 E1_DerP2_DerF2 PF02221.10 KND97681.1 - 1.8e-24 86.5 0.3 2.1e-24 86.2 0.2 1.1 1 0 0 1 1 1 1 ML domain DUF4625 PF15418.1 KND97681.1 - 0.058 13.5 0.0 0.077 13.1 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4625) Sulfate_transp PF00916.15 KND97682.1 - 1.7e-47 161.7 5.6 3.7e-47 160.6 3.9 1.6 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 KND97682.1 - 1.3e-10 40.6 0.1 3.1e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.24 KND97682.1 - 0.0031 17.2 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PCDO_beta_N PF12391.3 KND97682.1 - 0.14 11.6 0.5 0.25 10.7 0.4 1.4 1 0 0 1 1 1 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal Peptidase_M28 PF04389.12 KND97683.1 - 0.0031 17.2 0.0 0.01 15.5 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M28 MFS_1 PF07690.11 KND97684.1 - 1.9e-13 49.9 32.8 1.1e-12 47.3 22.6 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KND97684.1 - 2e-07 29.6 18.2 1.7e-06 26.5 5.9 2.4 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KND97684.1 - 0.0019 16.6 2.2 0.0019 16.6 1.5 3.4 2 1 0 2 2 2 1 MFS/sugar transport protein SH3_1 PF00018.23 KND97685.1 - 2.3e-05 23.6 0.2 0.00027 20.2 0.0 2.4 1 1 1 2 2 2 1 SH3 domain SH3_9 PF14604.1 KND97685.1 - 0.0008 18.9 0.1 0.096 12.2 0.1 2.5 1 1 1 2 2 2 2 Variant SH3 domain HEAT_EZ PF13513.1 KND97686.1 - 8.6e-23 80.1 23.9 1.1e-10 41.6 0.0 11.1 11 3 2 13 13 12 5 HEAT-like repeat HEAT_2 PF13646.1 KND97686.1 - 2.3e-22 79.0 7.7 4.3e-06 26.9 0.0 8.2 6 2 1 7 7 7 4 HEAT repeats HEAT PF02985.17 KND97686.1 - 3.7e-16 57.6 36.3 0.017 15.1 0.1 12.5 14 0 0 14 14 14 4 HEAT repeat Vac14_Fab1_bd PF12755.2 KND97686.1 - 5.8e-12 45.8 0.2 0.0023 18.2 0.0 5.1 4 1 1 5 5 5 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KND97686.1 - 5.5e-08 32.8 5.9 0.7 9.7 0.1 6.1 4 2 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KND97686.1 - 5.4e-07 29.2 1.8 2.3 7.4 0.0 5.8 4 1 0 4 4 4 2 CLASP N terminal IBN_N PF03810.14 KND97686.1 - 0.00026 20.8 0.0 0.0022 17.8 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 KND97686.1 - 0.0004 18.8 2.4 0.1 10.9 0.0 3.8 3 1 0 4 4 4 1 Adaptin N terminal region Arm PF00514.18 KND97686.1 - 0.00081 19.1 10.2 1.5 8.7 0.0 6.6 7 0 0 7 7 6 1 Armadillo/beta-catenin-like repeat RINT1_TIP1 PF04437.8 KND97686.1 - 0.051 12.1 0.0 0.095 11.2 0.0 1.3 1 0 0 1 1 1 0 RINT-1 / TIP-1 family MMS19_C PF12460.3 KND97686.1 - 0.11 11.2 2.8 2 7.0 0.0 3.5 3 2 1 4 4 4 0 RNAPII transcription regulator C-terminal PIG-P PF08510.7 KND97687.1 - 5.1e-32 110.1 4.1 6.5e-32 109.8 2.9 1.1 1 0 0 1 1 1 1 PIG-P DUF4131 PF13567.1 KND97687.1 - 0.22 10.9 2.2 0.29 10.5 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Arteri_Gl PF00951.13 KND97687.1 - 0.91 9.0 4.4 1.1 8.7 3.0 1.1 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein CPSase_L_D2 PF02786.12 KND97688.1 - 2.1e-110 366.9 0.0 4.8e-84 280.8 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 KND97688.1 - 6e-40 135.8 0.0 1.5e-39 134.5 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 KND97688.1 - 2.2e-39 135.1 0.0 7.4e-22 77.9 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 KND97688.1 - 2.3e-36 124.2 0.0 1.9e-17 63.3 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 KND97688.1 - 1.4e-24 86.4 0.0 1.6e-09 37.0 0.0 4.0 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KND97688.1 - 2.8e-22 78.8 0.0 3e-10 39.7 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KND97688.1 - 4.2e-16 58.9 0.1 6e-08 32.3 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 KND97688.1 - 3.8e-10 39.5 0.0 1.4e-05 24.6 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 KND97688.1 - 4.2e-05 22.8 0.0 0.13 11.5 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.9 KND97688.1 - 0.00012 22.0 0.1 0.55 10.0 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 KND97688.1 - 0.0003 20.3 0.0 0.077 12.5 0.0 2.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain MGS PF02142.17 KND97688.1 - 0.008 16.0 0.0 0.04 13.8 0.0 2.3 2 0 0 2 2 2 1 MGS-like domain TrkA_N PF02254.13 KND97688.1 - 0.012 15.6 1.1 0.055 13.4 0.0 2.7 3 0 0 3 3 3 0 TrkA-N domain Epimerase PF01370.16 KND97688.1 - 0.013 14.9 0.0 0.21 10.9 0.0 2.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Lactamase_B PF00753.22 KND97688.1 - 0.073 12.7 0.0 0.2 11.2 0.0 1.8 2 0 0 2 2 1 0 Metallo-beta-lactamase superfamily DUF2652 PF10851.3 KND97688.1 - 0.13 12.2 0.0 16 5.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2652) SNAP PF14938.1 KND97689.1 - 1.8e-100 335.7 8.4 2e-100 335.6 5.9 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KND97689.1 - 1.1e-06 28.4 5.4 6.7e-05 22.7 0.9 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KND97689.1 - 1.2e-06 28.0 7.4 0.00033 20.2 1.6 3.3 1 1 2 3 3 3 2 TPR repeat TPR_14 PF13428.1 KND97689.1 - 1.9e-06 28.0 0.3 0.73 10.6 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KND97689.1 - 1.5e-05 25.5 0.3 0.036 14.7 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KND97689.1 - 3.5e-05 23.4 15.8 0.15 12.0 0.0 5.5 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 KND97689.1 - 3.6e-05 23.1 15.5 0.069 12.7 1.1 4.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KND97689.1 - 0.00025 20.6 5.1 0.13 12.0 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KND97689.1 - 0.00044 20.5 7.3 0.067 13.6 0.4 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat Foie-gras_1 PF11817.3 KND97689.1 - 0.00089 18.8 3.3 0.04 13.4 0.1 2.9 1 1 3 4 4 4 1 Foie gras liver health family 1 TPR_8 PF13181.1 KND97689.1 - 0.0021 17.7 12.7 0.0043 16.7 0.1 4.2 4 1 1 5 5 5 2 Tetratricopeptide repeat RPN7 PF10602.4 KND97689.1 - 0.0025 17.2 2.1 0.11 11.8 0.4 3.0 1 1 1 2 2 2 1 26S proteasome subunit RPN7 TPR_19 PF14559.1 KND97689.1 - 0.018 15.3 3.7 0.34 11.2 0.2 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KND97689.1 - 0.32 11.1 11.0 0.37 10.9 0.6 3.4 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 NSF PF02071.15 KND97689.1 - 2 9.3 12.4 6.7 7.7 0.0 5.9 7 0 0 7 7 6 0 Aromatic-di-Alanine (AdAR) repeat IncA PF04156.9 KND97691.1 - 0.034 13.7 1.5 0.042 13.4 1.0 1.1 1 0 0 1 1 1 0 IncA protein HR1 PF02185.11 KND97691.1 - 0.037 13.7 4.2 0.046 13.4 2.9 1.1 1 0 0 1 1 1 0 Hr1 repeat Prefoldin PF02996.12 KND97691.1 - 0.074 12.7 3.2 0.1 12.2 2.2 1.2 1 0 0 1 1 1 0 Prefoldin subunit WXG100 PF06013.7 KND97691.1 - 0.076 13.0 0.8 0.19 11.7 0.6 1.7 1 1 0 1 1 1 0 Proteins of 100 residues with WXG SieB PF14163.1 KND97691.1 - 0.11 12.0 0.3 0.12 11.9 0.2 1.1 1 0 0 1 1 1 0 Superinfection exclusion protein B Spc24 PF08286.6 KND97691.1 - 0.43 10.2 7.3 0.49 10.0 5.0 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Nnf1 PF03980.9 KND97692.1 - 1.3e-23 83.1 6.3 1.3e-23 83.1 4.4 1.5 2 0 0 2 2 2 1 Nnf1 HXXSHH PF07586.6 KND97692.1 - 0.035 13.0 3.7 0.13 11.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1552) Ribosomal_S15 PF00312.17 KND97693.1 - 4e-19 68.1 0.2 1.2e-18 66.6 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein S15 DP PF08781.5 KND97693.1 - 0.0018 17.9 2.5 0.0022 17.7 0.5 2.0 2 0 0 2 2 2 1 Transcription factor DP PseudoU_synth_2 PF00849.17 KND97695.1 - 1.6e-23 83.3 0.0 3e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF2088 PF09861.4 KND97697.1 - 0.057 12.4 0.0 0.14 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2088) GATA PF00320.22 KND97698.1 - 7.5e-15 53.9 4.0 2.2e-14 52.5 2.7 1.9 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 KND97698.1 - 0.0081 15.4 0.3 0.015 14.6 0.2 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding PGM_PMM_I PF02878.11 KND97699.1 - 2.5e-36 124.2 0.3 3.9e-36 123.5 0.2 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 KND97699.1 - 6.1e-24 84.2 0.0 1.4e-23 83.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 KND97699.1 - 7.4e-14 51.9 0.0 9.7e-13 48.3 0.0 2.5 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KND97699.1 - 3e-10 39.9 0.0 7.6e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Med19 PF10278.4 KND97700.1 - 0.44 10.2 10.7 0.46 10.1 7.4 1.0 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Aminotran_1_2 PF00155.16 KND97701.1 - 8.1e-81 271.7 0.0 9.2e-81 271.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4250 PF14056.1 KND97701.1 - 0.012 15.3 0.6 0.03 14.0 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) ADH_zinc_N PF00107.21 KND97704.1 - 3.9e-27 94.3 0.0 6.4e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KND97704.1 - 2.1e-12 46.7 0.0 4.4e-12 45.7 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KND97704.1 - 6.2e-11 43.2 0.1 5.7e-10 40.1 0.0 2.2 2 1 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KND97704.1 - 0.018 15.0 0.5 0.03 14.3 0.3 1.3 1 0 0 1 1 1 0 NADH(P)-binding Methyltransf_18 PF12847.2 KND97704.1 - 0.091 13.3 0.1 0.34 11.5 0.1 1.9 1 1 1 2 2 2 0 Methyltransferase domain Sugar_tr PF00083.19 KND97705.1 - 2e-148 494.7 34.2 2.3e-148 494.5 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND97705.1 - 4.6e-30 104.5 30.9 7.9e-27 93.8 11.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4173 PF13777.1 KND97705.1 - 1.5 8.0 10.4 0.044 13.0 0.4 2.9 2 1 2 4 4 4 0 Domain of unknown function (DUF4173) DUF3984 PF13136.1 KND97706.1 - 0.064 12.4 0.7 0.09 11.9 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF4519 PF15012.1 KND97706.1 - 2.5 8.0 7.1 5 7.1 4.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Sugar_tr PF00083.19 KND97707.1 - 2.8e-153 510.7 32.0 3.2e-153 510.5 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND97707.1 - 1.8e-29 102.5 27.4 1.1e-26 93.4 9.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KND97707.1 - 0.00047 18.5 1.8 0.00097 17.4 1.3 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ni_hydr_CYTB PF01292.15 KND97707.1 - 0.16 11.3 9.3 4 6.7 3.1 3.6 4 1 0 4 4 4 0 Prokaryotic cytochrome b561 Cytochrom_B_N PF00033.14 KND97707.1 - 0.23 10.7 7.0 0.05 12.9 0.7 2.8 4 0 0 4 4 4 0 Cytochrome b(N-terminal)/b6/petB DUF3935 PF13071.1 KND97710.1 - 0.058 13.7 0.1 0.1 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3935) DUF3321 PF11968.3 KND97711.1 - 5.9e-85 284.3 0.0 7.6e-85 284.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 KND97711.1 - 0.0016 18.2 0.0 0.0043 16.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain UPF0697 PF15117.1 KND97711.1 - 0.036 13.8 0.1 1.9 8.2 0.1 3.2 4 0 0 4 4 4 0 Uncharacterised protein family UPF0697 DEAD PF00270.24 KND97713.1 - 1e-37 129.2 0.0 2.2e-37 128.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND97713.1 - 4.6e-24 84.0 0.0 1.3e-23 82.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KND97713.1 - 0.0096 16.0 0.0 0.039 14.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain DDHD PF02862.12 KND97713.1 - 0.77 9.5 7.2 0.45 10.2 2.2 2.1 2 0 0 2 2 2 0 DDHD domain eRF1_2 PF03464.10 KND97715.1 - 3e-46 157.0 0.1 4.9e-46 156.3 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KND97715.1 - 9.1e-36 122.5 0.1 1.9e-35 121.5 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 KND97715.1 - 5.4e-28 97.2 0.0 8.6e-28 96.5 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 Tnp_DNA_bind PF14706.1 KND97715.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Transposase DNA-binding CDC50 PF03381.10 KND97717.1 - 2.5e-88 295.8 1.8 3.6e-88 295.3 1.3 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family IncA PF04156.9 KND97717.1 - 0.089 12.3 0.0 0.089 12.3 0.0 2.7 4 0 0 4 4 4 0 IncA protein Pkinase PF00069.20 KND97720.1 - 8.8e-60 202.0 0.0 3e-59 200.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND97720.1 - 6.4e-45 153.2 0.0 1.5e-44 152.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND97720.1 - 6.6e-05 22.0 0.0 0.00015 20.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pex2_Pex12 PF04757.9 KND97721.1 - 1.7e-36 125.7 9.4 2.3e-36 125.3 6.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.1 KND97721.1 - 2.2e-05 24.0 5.4 4.2e-05 23.1 3.7 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KND97721.1 - 5e-05 23.0 5.7 9.3e-05 22.1 3.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KND97721.1 - 0.0003 20.4 6.1 0.00047 19.7 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KND97721.1 - 0.0003 20.3 6.9 0.00096 18.7 4.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KND97721.1 - 0.00031 20.7 3.8 0.00031 20.7 2.7 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KND97721.1 - 0.00056 19.7 3.4 0.00056 19.7 2.4 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KND97721.1 - 0.037 13.7 0.3 0.082 12.6 0.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DUF3788 PF12663.2 KND97721.1 - 0.12 12.0 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3788) zf-rbx1 PF12678.2 KND97721.1 - 0.26 11.3 2.0 0.54 10.3 1.4 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 KND97721.1 - 0.34 10.5 5.9 0.75 9.4 4.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE PF01363.16 KND97721.1 - 1.1 9.2 5.5 2.8 7.8 3.8 1.8 1 1 0 1 1 1 0 FYVE zinc finger WD40 PF00400.27 KND97722.1 - 2.3e-14 52.6 1.1 0.0054 16.5 0.0 6.5 5 1 0 5 5 5 4 WD domain, G-beta repeat PQQ_2 PF13360.1 KND97722.1 - 0.011 15.2 0.0 0.089 12.2 0.0 2.4 2 1 0 2 2 2 0 PQQ-like domain SART-1 PF03343.8 KND97723.1 - 6.1e-59 199.9 59.7 4.1e-45 154.2 32.9 3.5 2 1 1 3 3 3 3 SART-1 family Fucose_iso_N2 PF07882.7 KND97723.1 - 0.023 14.3 4.2 0.14 11.8 0.1 3.3 3 0 0 3 3 3 0 L-fucose isomerase, second N-terminal domain E1-E2_ATPase PF00122.15 KND97724.1 - 8.3e-43 146.0 0.2 8.3e-43 146.0 0.1 2.3 2 1 0 2 2 2 1 E1-E2 ATPase HMA PF00403.21 KND97724.1 - 4.1e-39 132.5 9.2 8.2e-13 48.2 0.2 4.0 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase PF00702.21 KND97724.1 - 8.6e-38 130.8 0.5 3.3e-37 128.9 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KND97724.1 - 2.9e-14 53.6 0.0 1.3e-13 51.6 0.0 2.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KND97724.1 - 0.0091 15.6 0.4 0.1 12.1 0.1 2.3 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase TMEMspv1-c74-12 PF11044.3 KND97727.1 - 2.5 7.7 5.2 4.2 6.9 3.6 1.4 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Xpo1 PF08389.7 KND97730.1 - 9.2e-24 84.0 11.3 1.1e-23 83.7 3.8 3.6 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 KND97730.1 - 4.3e-05 23.3 0.7 0.0011 18.7 0.2 3.1 2 1 0 2 2 2 1 Importin-beta N-terminal domain HEAT_EZ PF13513.1 KND97730.1 - 0.02 15.3 0.0 6.4 7.3 0.1 4.1 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.17 KND97730.1 - 0.079 13.0 0.7 1.3e+02 3.0 0.1 5.3 6 0 0 6 6 6 0 HEAT repeat Guanylate_kin PF00625.16 KND97731.1 - 5.3e-67 224.8 0.0 5.9e-67 224.6 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 KND97731.1 - 1.1e-06 28.9 0.0 3.8e-06 27.2 0.0 1.9 1 1 1 2 2 1 1 AAA domain AAA_16 PF13191.1 KND97731.1 - 1.4e-06 28.4 0.2 1.2e-05 25.4 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KND97731.1 - 2.8e-06 28.1 0.1 1.6e-05 25.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KND97731.1 - 3.2e-06 27.0 0.1 2.3e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KND97731.1 - 8.3e-06 25.9 0.1 7.7e-05 22.8 0.0 2.3 2 1 0 2 2 2 1 RNA helicase AAA_22 PF13401.1 KND97731.1 - 5.7e-05 23.2 0.0 0.00018 21.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KND97731.1 - 0.00017 22.0 0.0 0.00026 21.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein AAA_19 PF13245.1 KND97731.1 - 0.00035 20.2 0.2 0.0039 16.9 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 KND97731.1 - 0.0005 20.0 0.0 0.0017 18.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KND97731.1 - 0.00058 19.6 0.1 0.00092 18.9 0.1 1.6 1 1 0 1 1 1 1 Archaeal ATPase ABC_tran PF00005.22 KND97731.1 - 0.0008 19.7 0.0 0.0011 19.3 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.1 KND97731.1 - 0.0012 18.7 0.0 0.0018 18.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KND97731.1 - 0.0013 17.9 0.0 0.0024 17.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KND97731.1 - 0.0015 18.4 0.1 0.0023 17.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 KND97731.1 - 0.0027 17.3 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain T2SE PF00437.15 KND97731.1 - 0.003 16.4 0.0 0.0054 15.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.24 KND97731.1 - 0.0033 17.6 0.3 0.0098 16.0 0.1 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KND97731.1 - 0.0036 16.9 0.3 0.0043 16.6 0.2 1.4 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 KND97731.1 - 0.004 16.8 0.1 0.0082 15.8 0.1 1.7 1 1 0 1 1 1 1 NTPase Viral_helicase1 PF01443.13 KND97731.1 - 0.0045 16.5 0.0 0.0076 15.7 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 KND97731.1 - 0.0067 15.9 0.6 0.013 15.0 0.1 1.7 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_5 PF07728.9 KND97731.1 - 0.0082 15.8 0.0 0.045 13.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 KND97731.1 - 0.0084 15.5 0.5 0.013 14.9 0.3 1.8 1 1 0 1 1 1 1 AAA-like domain AAA_2 PF07724.9 KND97731.1 - 0.0088 15.9 0.0 0.24 11.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF2075 PF09848.4 KND97731.1 - 0.0092 14.9 0.1 0.067 12.1 0.1 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PilX PF13681.1 KND97731.1 - 0.012 16.1 0.1 0.03 14.8 0.0 1.6 2 0 0 2 2 1 0 Type IV pilus assembly protein PilX C-term AAA_25 PF13481.1 KND97731.1 - 0.012 15.0 0.3 0.1 12.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.10 KND97731.1 - 0.013 14.1 0.0 0.016 13.9 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein KAP_NTPase PF07693.9 KND97731.1 - 0.017 14.1 0.1 0.026 13.5 0.1 1.6 1 1 0 1 1 1 0 KAP family P-loop domain MobB PF03205.9 KND97731.1 - 0.026 14.2 0.0 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KND97731.1 - 0.032 13.8 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KND97731.1 - 0.034 13.5 0.1 0.1 12.0 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 KND97731.1 - 0.036 13.1 0.2 0.13 11.3 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.1 KND97731.1 - 0.082 13.2 2.8 0.14 12.4 1.9 1.8 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.1 KND97731.1 - 0.24 11.3 1.0 0.51 10.2 0.3 1.7 1 1 1 2 2 2 0 AAA domain Pkinase PF00069.20 KND97734.1 - 1.2e-71 240.9 0.0 1.5e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND97734.1 - 3.8e-28 98.2 0.0 6.2e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND97734.1 - 5.8e-05 22.1 0.0 8.8e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KND97734.1 - 0.00058 18.7 0.1 0.00095 18.0 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 KND97734.1 - 0.0039 16.9 0.0 0.0094 15.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KND97734.1 - 0.007 15.4 0.2 0.017 14.1 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RVT_1 PF00078.22 KND97734.1 - 0.096 12.0 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1263 PF06882.7 KND97735.1 - 0.065 12.8 0.1 0.15 11.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1263) Pyr_redox_2 PF07992.9 KND97736.1 - 3.3e-11 43.4 0.0 4.7e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND97736.1 - 2.2e-08 34.3 0.4 1.2e-07 31.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KND97736.1 - 2e-05 24.4 1.5 0.068 12.9 0.0 3.5 3 1 1 4 4 4 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 KND97736.1 - 5e-05 22.3 0.0 7.8e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KND97736.1 - 0.00048 20.2 0.2 0.0018 18.3 0.1 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 KND97736.1 - 0.0021 17.8 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.7 KND97736.1 - 0.0077 15.1 0.0 0.016 14.1 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein adh_short PF00106.20 KND97739.1 - 3.5e-22 79.0 0.1 5e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND97739.1 - 2.2e-09 37.4 0.1 3.2e-09 36.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND97739.1 - 3.4e-05 23.6 0.2 0.00011 21.9 0.1 1.8 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KND97739.1 - 0.00018 21.5 0.0 0.00033 20.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 KND97739.1 - 0.026 14.6 0.5 0.088 12.9 0.1 1.9 1 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase MFS_1_like PF12832.2 KND97739.1 - 0.071 12.9 1.4 0.3 10.8 0.0 2.7 2 1 2 4 4 4 0 MFS_1 like family ApbA PF02558.11 KND97739.1 - 0.082 12.3 0.0 0.32 10.4 0.0 2.0 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Mitochondr_Som1 PF11093.3 KND97740.1 - 1.6e-31 107.9 1.4 2.1e-31 107.5 1.0 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 UQ_con PF00179.21 KND97741.1 - 5.2e-18 64.8 0.0 5.9e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KND97741.1 - 0.0079 16.0 0.0 0.0083 16.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain MAD PF05557.8 KND97742.1 - 3.1e-20 71.9 68.8 4.6e-20 71.3 47.7 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein CCDC144C PF14915.1 KND97742.1 - 0.0058 15.5 20.6 0.0058 15.5 14.3 4.3 4 1 1 5 5 5 2 CCDC144C protein coiled-coil region Hemerythrin PF01814.18 KND97742.1 - 1.2 9.3 10.2 0.99 9.5 0.3 4.2 4 0 0 4 4 4 0 Hemerythrin HHE cation binding domain VPS9 PF02204.13 KND97742.1 - 1.9 8.5 8.2 10 6.1 0.1 3.3 3 0 0 3 3 3 0 Vacuolar sorting protein 9 (VPS9) domain WXG100 PF06013.7 KND97742.1 - 3.2 7.8 10.1 3.2 7.8 0.1 4.9 5 0 0 5 5 5 0 Proteins of 100 residues with WXG PRP1_N PF06424.7 KND97743.1 - 3.1e-31 108.4 0.0 3.1e-31 108.4 0.0 2.9 3 0 0 3 3 3 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 KND97743.1 - 4.6e-19 67.1 7.9 0.063 13.9 0.7 10.2 6 3 5 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.1 KND97743.1 - 8.1e-13 48.5 17.0 0.0027 18.0 0.4 7.6 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 KND97743.1 - 9.1e-10 38.0 6.4 0.096 12.3 0.0 7.0 6 2 3 9 9 9 4 TPR repeat TPR_16 PF13432.1 KND97743.1 - 2.1e-09 37.7 1.2 2 9.1 0.0 6.1 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 KND97743.1 - 1.2e-06 28.2 4.9 4.6 7.6 0.0 7.4 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.12 KND97743.1 - 1.6e-06 27.5 7.5 0.82 9.7 0.0 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 KND97743.1 - 4.3e-06 26.5 11.7 0.056 13.3 0.0 7.0 7 1 0 7 7 7 2 Tetratricopeptide repeat Suf PF05843.9 KND97743.1 - 0.023 14.4 0.0 0.32 10.7 0.0 2.6 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) CAF1C_H4-bd PF12265.3 KND97744.1 - 7.8e-19 67.3 0.0 1.7e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 KND97744.1 - 1e-18 66.4 16.9 8.7e-07 28.5 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat Kelch_4 PF13418.1 KND97745.1 - 3.9e-41 138.5 4.5 2.4e-08 33.6 0.0 6.8 6 2 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 KND97745.1 - 1.1e-37 127.3 0.1 3e-09 36.7 0.0 7.2 7 0 0 7 7 7 4 Galactose oxidase, central domain DUF4110 PF13422.1 KND97745.1 - 3.8e-28 97.1 0.0 3.8e-28 97.1 0.0 4.7 3 2 1 4 4 4 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.1 KND97745.1 - 3.2e-26 90.3 5.1 2.1e-06 27.6 0.0 6.2 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.1 KND97745.1 - 1.2e-18 66.5 4.7 0.00068 19.5 0.0 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 KND97745.1 - 7.2e-16 57.4 13.9 4.4e-07 29.3 0.0 6.3 5 1 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 KND97745.1 - 3.9e-12 45.4 15.5 0.00029 20.5 0.1 6.2 6 1 0 6 6 6 4 Kelch motif DUF2724 PF10893.3 KND97745.1 - 0.28 11.0 0.0 0.28 11.0 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2724) TFIIA PF03153.8 KND97745.1 - 0.89 9.3 35.9 0.016 15.1 14.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RrnaAD PF00398.15 KND97747.1 - 4.3e-63 212.8 0.0 5.4e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KND97747.1 - 7.1e-09 35.7 0.0 1.3e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND97747.1 - 3.5e-05 24.3 0.0 7.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KND97747.1 - 0.00016 21.0 0.0 0.00039 19.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Met_10 PF02475.11 KND97747.1 - 0.0021 17.6 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_12 PF08242.7 KND97747.1 - 0.0025 18.2 0.0 0.0058 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND97747.1 - 0.0032 17.0 0.0 0.0042 16.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KND97747.1 - 0.0038 16.3 0.0 0.0062 15.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 KND97747.1 - 0.0042 16.6 0.0 0.0069 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 KND97747.1 - 0.019 14.7 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 KND97747.1 - 0.035 13.3 0.0 0.081 12.1 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase KAR9 PF08580.5 KND97749.1 - 8.5e-41 140.0 5.8 1.3e-40 139.3 4.0 1.3 1 0 0 1 1 1 1 Yeast cortical protein KAR9 Ni_hydr_CYTB PF01292.15 KND97750.1 - 0.079 12.3 0.0 0.089 12.1 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 PGM_PMM_I PF02878.11 KND97751.1 - 2.2e-16 59.5 0.0 2.3e-08 33.6 0.0 2.7 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KND97751.1 - 6.1e-13 49.0 1.0 7.1e-12 45.5 0.1 2.8 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KND97751.1 - 7.1e-13 48.3 0.7 2.5e-12 46.6 0.2 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 KND97751.1 - 0.0015 18.5 0.1 0.0055 16.7 0.0 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III TFIIA_gamma_N PF02268.11 KND97751.1 - 0.072 12.6 0.2 6 6.5 0.0 2.5 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain SNase PF00565.12 KND97753.1 - 3.5e-25 88.3 0.2 4.9e-25 87.8 0.1 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue EAF PF09816.4 KND97754.1 - 3.9e-12 46.0 0.0 1e-11 44.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor zf-ZPR1 PF03367.8 KND97755.1 - 0.0083 15.2 0.2 0.013 14.6 0.1 1.4 1 0 0 1 1 1 1 ZPR1 zinc-finger domain UDPG_MGDP_dh_N PF03721.9 KND97755.1 - 0.033 13.5 0.6 0.052 12.9 0.4 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF3890 PF13029.1 KND97755.1 - 0.068 13.2 0.4 0.25 11.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3890) MutS_III PF05192.13 KND97755.1 - 0.1 12.3 3.6 0.12 12.0 2.5 1.1 1 0 0 1 1 1 0 MutS domain III GAS PF13851.1 KND97756.1 - 0.001 18.2 27.5 0.67 9.1 14.3 3.1 2 1 0 2 2 2 2 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 KND97756.1 - 0.04 13.7 26.2 0.23 11.2 1.5 4.2 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF4140 PF13600.1 KND97756.1 - 0.11 12.9 0.2 0.11 12.9 0.1 3.8 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) bZIP_1 PF00170.16 KND97756.1 - 0.11 12.4 27.1 0.057 13.3 1.7 5.0 3 2 1 5 5 5 0 bZIP transcription factor Rootletin PF15035.1 KND97756.1 - 0.12 12.3 20.7 0.078 12.9 5.5 3.9 2 1 2 4 4 4 0 Ciliary rootlet component, centrosome cohesion KH_5 PF13184.1 KND97756.1 - 0.17 11.6 1.1 0.67 9.7 0.0 2.5 2 0 0 2 2 2 0 NusA-like KH domain IncA PF04156.9 KND97756.1 - 0.21 11.1 27.3 0.42 10.1 4.7 3.3 1 1 2 3 3 3 0 IncA protein ERM PF00769.14 KND97756.1 - 0.24 10.8 20.1 0.3 10.5 8.2 2.7 1 1 1 2 2 2 0 Ezrin/radixin/moesin family NEMO PF11577.3 KND97756.1 - 0.37 10.5 9.2 2.8 7.7 0.7 3.5 3 0 0 3 3 3 0 NF-kappa-B essential modulator NEMO ADIP PF11559.3 KND97756.1 - 0.39 10.6 26.1 0.19 11.5 3.2 3.6 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 KND97756.1 - 0.48 9.9 21.1 0.084 12.3 2.5 3.8 3 1 1 4 4 4 0 Septum formation initiator DivIVA PF05103.8 KND97756.1 - 0.49 10.4 23.0 25 4.9 0.1 4.4 1 1 2 3 3 3 0 DivIVA protein DUF904 PF06005.7 KND97756.1 - 0.53 10.6 20.7 2.4 8.5 4.0 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF904) Hemerythrin PF01814.18 KND97756.1 - 0.81 9.8 7.3 0.31 11.1 0.8 2.6 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain FliJ PF02050.11 KND97756.1 - 1 9.4 18.5 0.19 11.7 1.9 3.3 3 1 1 4 4 3 0 Flagellar FliJ protein DUF3508 PF12018.3 KND97756.1 - 1.3 7.9 11.0 0.15 11.0 2.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3508) DUF3450 PF11932.3 KND97756.1 - 1.5 8.0 14.3 3.9 6.6 0.9 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF3450) DUF948 PF06103.6 KND97756.1 - 1.6 8.6 7.1 1.3 8.9 0.2 3.5 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.4 KND97756.1 - 2.1 8.5 18.7 0.29 11.2 1.1 4.0 1 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Snapin_Pallidin PF14712.1 KND97756.1 - 2.3 8.5 14.3 1.4 9.2 2.2 3.9 1 1 1 3 3 3 0 Snapin/Pallidin CENP-F_leu_zip PF10473.4 KND97756.1 - 2.5 7.9 29.5 1.1 9.0 4.5 4.1 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KND97756.1 - 2.5 7.2 9.6 0.88 8.6 0.7 2.7 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 KND97756.1 - 3.4 7.4 13.8 0.74 9.6 0.4 3.6 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.6 KND97756.1 - 4.4 7.7 14.1 8.9 6.7 3.0 3.9 2 1 0 3 3 3 0 Syntaxin 6, N-terminal FlaC_arch PF05377.6 KND97756.1 - 5.5 6.9 12.8 0.94 9.4 0.3 3.5 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) ORF6C PF10552.4 KND97756.1 - 7 6.4 10.6 0.2 11.4 0.6 2.9 2 1 2 4 4 4 0 ORF6C domain DUF972 PF06156.8 KND97756.1 - 9.3 6.6 21.2 1.5 9.1 2.4 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF972) WD40 PF00400.27 KND97757.1 - 7.9e-07 28.7 0.1 0.0013 18.5 0.3 4.8 7 0 0 7 7 7 1 WD domain, G-beta repeat Aminotran_5 PF00266.14 KND97759.1 - 1.9e-22 79.5 0.1 2.2e-22 79.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KND97759.1 - 0.00013 21.0 0.1 0.00018 20.6 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KND97759.1 - 0.00017 20.0 0.5 0.00027 19.3 0.4 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.14 KND97759.1 - 0.0045 16.8 0.6 0.01 15.7 0.1 1.8 2 0 0 2 2 2 1 B12 binding domain DnaJ PF00226.26 KND97760.1 - 9.9e-21 73.2 1.5 2.8e-20 71.8 1.1 1.8 1 0 0 1 1 1 1 DnaJ domain Recombinase PF07508.8 KND97760.1 - 0.028 14.6 1.3 4.5 7.5 0.0 2.8 2 1 1 3 3 3 0 Recombinase DUF413 PF04219.7 KND97760.1 - 0.077 12.7 0.3 0.21 11.3 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF DNA_topoisoIV PF00521.15 KND97761.1 - 2.5e-125 418.6 0.0 2.5e-125 418.6 0.0 1.7 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 KND97761.1 - 2.1e-33 114.9 6.0 5.5e-33 113.6 4.2 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 KND97761.1 - 1.5e-11 44.1 0.0 7e-11 41.9 0.0 2.2 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 KND97761.1 - 2e-10 40.3 0.0 6.3e-10 38.7 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2576 PF10845.3 KND97761.1 - 0.093 11.9 0.4 0.21 10.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) DUF4557 PF15101.1 KND97764.1 - 1.4 8.7 7.7 2.2 8.0 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Rdx PF10262.4 KND97765.1 - 3.4e-09 36.6 0.0 4.7e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Rdx family DUF3493 PF11998.3 KND97766.1 - 0.084 12.7 0.7 0.095 12.5 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3493) GATA PF00320.22 KND97768.1 - 1.2e-16 59.7 4.7 2.9e-16 58.5 3.3 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 KND97768.1 - 5.1e-08 32.3 6.9 9.8e-08 31.4 4.8 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.7 KND97768.1 - 0.2 10.9 1.8 0.22 10.8 0.3 1.8 2 0 0 2 2 2 0 TFIIB zinc-binding CUE PF02845.11 KND97772.1 - 2.6e-10 39.5 0.1 8.9e-10 37.8 0.0 1.9 2 0 0 2 2 2 1 CUE domain Vfa1 PF08432.5 KND97772.1 - 3.2 7.7 29.4 3.6 7.5 16.5 2.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 MIP-T3 PF10243.4 KND97772.1 - 8.9 4.6 33.7 19 3.5 23.5 1.4 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 NDUF_B7 PF05676.8 KND97774.1 - 6e-10 38.3 1.1 8e-10 37.9 0.7 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.4 KND97774.1 - 0.044 13.8 1.0 0.066 13.2 0.7 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 KND97774.1 - 0.42 10.6 6.1 4.3 7.4 4.2 2.0 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb GATA PF00320.22 KND97779.1 - 3.5e-16 58.2 5.1 6.3e-16 57.4 3.5 1.5 1 0 0 1 1 1 1 GATA zinc finger GSu_C4xC__C2xCH PF09698.5 KND97779.1 - 0.2 11.8 3.5 0.66 10.2 2.4 1.8 1 0 0 1 1 1 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) Nudix_N_2 PF14803.1 KND97779.1 - 0.21 11.2 2.1 0.47 10.1 1.4 1.5 1 0 0 1 1 1 0 Nudix N-terminal Hydrolase_6 PF13344.1 KND97782.1 - 3.9e-22 78.0 0.0 7e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KND97782.1 - 3.4e-20 71.5 0.0 1.2e-19 69.7 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 KND97782.1 - 8.5e-06 26.0 0.1 0.016 15.4 0.0 3.6 3 1 1 4 4 4 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KND97782.1 - 0.00026 21.4 0.0 0.27 11.6 0.0 3.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase TP_methylase PF00590.15 KND97783.1 - 5.5e-43 147.1 0.0 1.7e-42 145.5 0.0 1.8 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 KND97783.1 - 2.6e-11 43.6 0.0 5.3e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KND97783.1 - 0.0017 17.6 0.2 0.16 11.3 0.0 2.5 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Tropomodulin PF03250.9 KND97784.1 - 0.1 12.1 0.0 0.11 12.0 0.0 1.0 1 0 0 1 1 1 0 Tropomodulin TMEMspv1-c74-12 PF11044.3 KND97784.1 - 2.2 7.9 5.6 33 4.1 3.5 2.2 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Nro1 PF12753.2 KND97785.1 - 1.6e-144 481.7 15.6 2.2e-144 481.3 10.8 1.2 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 TPR_14 PF13428.1 KND97785.1 - 0.26 12.0 1.8 30 5.6 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat Exonuc_VII_S PF02609.11 KND97785.1 - 0.31 10.8 2.8 1.4 8.7 0.0 3.1 3 0 0 3 3 3 0 Exonuclease VII small subunit Acyltransferase PF01553.16 KND97787.1 - 2.3e-08 33.5 0.0 1.1e-06 28.1 0.0 2.9 2 1 0 2 2 2 1 Acyltransferase DUF4096 PF13340.1 KND97787.1 - 0.11 12.3 0.0 3.9 7.3 0.0 2.6 2 0 0 2 2 2 0 Putative transposase of IS4/5 family (DUF4096) TRAPP PF04051.11 KND97788.1 - 4.7e-35 120.3 0.0 5.7e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component FA_hydroxylase PF04116.8 KND97790.1 - 3.1e-18 66.2 4.3 3.1e-18 66.2 2.9 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Methyltransf_11 PF08241.7 KND97791.1 - 4.6e-16 59.0 0.0 9.8e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND97791.1 - 2.4e-12 46.7 0.0 4e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND97791.1 - 2.7e-10 40.4 0.0 5.6e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND97791.1 - 5e-10 39.9 0.0 1.1e-09 38.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND97791.1 - 1.2e-09 38.5 0.0 2.5e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND97791.1 - 2.4e-08 33.8 0.0 4.3e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND97791.1 - 1.6e-07 30.6 0.0 2.3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KND97791.1 - 3.8e-05 23.7 0.0 0.00012 22.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KND97791.1 - 0.00011 21.6 0.0 0.00025 20.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 KND97791.1 - 0.0011 18.0 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 KND97791.1 - 0.0036 17.0 0.0 0.0055 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 KND97791.1 - 0.0056 15.5 0.0 0.0086 14.9 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_15 PF09445.5 KND97791.1 - 0.037 13.5 0.0 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Pirin PF02678.11 KND97792.1 - 9e-27 93.0 0.1 2e-26 91.9 0.1 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 KND97792.1 - 3.2e-19 68.9 0.0 8.5e-19 67.5 0.0 1.7 2 0 0 2 2 2 1 Pirin C-terminal cupin domain CDC27 PF09507.5 KND97793.1 - 1e-27 97.4 29.6 1.8e-27 96.6 20.5 1.4 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 HTH_Tnp_ISL3 PF13542.1 KND97793.1 - 0.13 11.5 0.1 0.24 10.5 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HNF-1_N PF04814.8 KND97794.1 - 0.28 11.2 3.3 7.3 6.6 0.1 3.1 3 1 0 3 3 3 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Pox_A_type_inc PF04508.7 KND97794.1 - 3.5 7.6 6.7 1.2 9.1 2.1 2.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF2891 PF11199.3 KND97796.1 - 0.14 10.7 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) DUF3371 PF11851.3 KND97798.1 - 0.064 13.9 3.5 0.11 13.2 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) zf-C3HC4_3 PF13920.1 KND97798.1 - 0.87 9.3 5.5 3.1 7.5 3.9 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KND97798.1 - 1.9 8.6 8.4 7.6 6.6 5.8 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KND97798.1 - 3.3 7.6 8.2 6.3 6.7 5.7 1.5 1 0 0 1 1 1 0 Ring finger domain LURAP PF14854.1 KND97799.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.1 1 0 0 1 1 1 0 Leucine rich adaptor protein HSL_N PF06350.7 KND97799.1 - 0.067 12.2 0.0 0.067 12.2 0.0 1.0 1 0 0 1 1 1 0 Hormone-sensitive lipase (HSL) N-terminus Pkinase PF00069.20 KND97801.1 - 5.3e-60 202.7 0.0 8.1e-60 202.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND97801.1 - 1.1e-34 119.7 0.0 1.8e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RskA PF10099.4 KND97801.1 - 0.0065 16.2 1.7 0.01 15.5 1.2 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA RIO1 PF01163.17 KND97801.1 - 0.0079 15.5 0.3 0.017 14.5 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.1 KND97801.1 - 0.011 14.7 0.0 0.024 13.6 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.6 KND97801.1 - 0.068 11.9 0.0 0.15 10.8 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 Selenoprotein_S PF06936.6 KND97806.1 - 0.11 11.9 2.3 0.12 11.8 1.6 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) UPF0542 PF15086.1 KND97807.1 - 1.5 8.5 8.3 1.8 8.3 5.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 TPR_12 PF13424.1 KND97809.1 - 0.00051 19.9 6.8 0.2 11.6 0.0 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KND97809.1 - 0.0084 15.9 1.7 3.4 7.8 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Peptidase_C97 PF05903.9 KND97809.1 - 0.038 13.7 0.2 0.073 12.8 0.1 1.4 1 0 0 1 1 1 0 PPPDE putative peptidase domain IFP_35_N PF07334.8 KND97809.1 - 0.059 13.3 1.9 0.17 11.8 0.2 2.4 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus TPR_1 PF00515.23 KND97809.1 - 0.084 12.5 4.3 1.6 8.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KND97809.1 - 0.097 12.3 3.4 6 6.5 0.1 3.2 3 0 0 3 3 3 0 TPR repeat Clat_adaptor_s PF01217.15 KND97810.1 - 3.3e-09 36.6 0.3 5.8e-09 35.8 0.1 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Adap_comp_sub PF00928.16 KND97810.1 - 1.1e-07 31.2 0.0 1.9e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family DUF3647 PF12363.3 KND97810.1 - 0.025 14.6 0.8 0.052 13.6 0.6 1.5 1 0 0 1 1 1 0 Phage protein PDEase_II PF02112.10 KND97811.1 - 6.8e-60 202.7 0.0 3.3e-59 200.5 0.0 1.8 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 KND97811.1 - 8.9e-07 28.6 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KND97811.1 - 0.036 13.7 0.9 0.07 12.7 0.7 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily zf-Di19 PF05605.7 KND97811.1 - 1 9.4 3.7 0.6 10.2 0.3 2.3 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Proteasome PF00227.21 KND97812.1 - 1.2e-26 93.1 0.0 1.5e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF410 PF04190.8 KND97815.1 - 5.9e-40 137.4 1.6 9.8e-40 136.7 1.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF410) DUF1175 PF06672.6 KND97815.1 - 0.066 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1175) NUDIX PF00293.23 KND97816.1 - 2.6e-14 53.0 0.1 3.6e-14 52.5 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain EF-hand_6 PF13405.1 KND97817.1 - 3.1e-09 35.9 0.1 0.0019 17.9 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KND97817.1 - 4.3e-06 25.6 0.4 4.2e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 KND97817.1 - 4.7e-06 26.6 0.0 1.6e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KND97817.1 - 6.3e-06 25.3 0.0 1.6e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 KND97817.1 - 0.00018 21.0 0.1 0.0052 16.3 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair Peptidase_S24 PF00717.18 KND97818.1 - 7.6e-08 31.8 0.1 1.8e-07 30.6 0.1 1.7 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 KND97818.1 - 0.00017 21.1 0.0 0.014 14.9 0.0 2.5 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 CHCH PF06747.8 KND97819.1 - 1.2e-05 25.0 13.0 0.0016 18.2 3.4 2.8 2 1 0 2 2 2 2 CHCH domain COX6B PF02297.12 KND97819.1 - 0.0016 18.4 9.0 0.043 13.8 0.2 2.2 1 1 1 2 2 2 2 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 KND97819.1 - 0.0045 16.9 11.6 0.026 14.5 4.9 2.8 1 1 2 3 3 3 2 Cytochrome c oxidase assembly protein PET191 PAN_3 PF08277.7 KND97819.1 - 0.12 12.0 1.2 0.13 11.9 0.1 1.6 1 1 0 1 1 1 0 PAN-like domain COX17 PF05051.8 KND97819.1 - 0.22 11.5 10.5 2.5 8.1 1.0 3.3 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) CD45 PF12567.3 KND97819.1 - 0.49 10.2 7.3 2.9 7.7 1.4 2.3 1 1 1 2 2 2 0 Leukocyte receptor CD45 DUF3551 PF12071.3 KND97819.1 - 0.53 9.8 5.0 0.2 11.2 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3551) DUF1903 PF08991.5 KND97819.1 - 0.94 9.6 10.3 0.064 13.4 2.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1903) NDUF_B7 PF05676.8 KND97819.1 - 0.98 8.8 9.3 0.77 9.2 1.2 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 KND97819.1 - 1.6 8.5 13.2 6.4 6.6 0.3 3.3 1 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 KND97819.1 - 3.2 7.7 12.8 8 6.4 2.3 3.1 1 1 2 3 3 3 0 Ubiquinol-cytochrome C reductase hinge protein LicD PF04991.8 KND97820.1 - 3.9e-38 131.6 0.6 5.7e-38 131.0 0.0 1.5 2 0 0 2 2 2 1 LicD family NAS PF03059.11 KND97820.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Nicotianamine synthase protein Folliculin PF11704.3 KND97821.1 - 7e-47 159.1 0.1 9.1e-47 158.7 0.1 1.1 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Atg14 PF10186.4 KND97822.1 - 4.3e-06 25.8 1.8 2.2e-05 23.5 1.2 1.8 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 SRP1_TIP1 PF00660.12 KND97823.1 - 1.5e-15 56.9 0.1 2e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 Seripauperin and TIP1 family UPF0126 PF03458.8 KND97823.1 - 0.012 15.2 0.3 0.012 15.2 0.2 2.1 2 0 0 2 2 2 0 UPF0126 domain CD99L2 PF12301.3 KND97823.1 - 0.47 10.1 2.3 0.68 9.6 1.6 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 DUF3246 PF11596.3 KND97823.1 - 0.81 8.9 7.1 1.1 8.4 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) VWA PF00092.23 KND97825.1 - 0.00011 22.0 0.0 0.0002 21.1 0.0 1.4 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.1 KND97825.1 - 0.00036 20.6 0.0 0.0015 18.6 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KND97825.1 - 0.0095 15.7 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus GPI2 PF06432.6 KND97826.1 - 5.6e-69 232.6 22.3 6.3e-69 232.4 15.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4300 PF14133.1 KND97827.1 - 0.012 14.9 0.5 0.012 14.9 0.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4300) RNase_H2-Ydr279 PF09468.5 KND97827.1 - 0.035 13.2 3.8 0.051 12.7 2.6 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) WXG100 PF06013.7 KND97827.1 - 0.073 13.0 2.0 10 6.1 0.6 2.6 2 0 0 2 2 2 0 Proteins of 100 residues with WXG QRPTase_C PF01729.14 KND97827.1 - 0.1 12.1 0.4 0.16 11.4 0.2 1.4 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Band_7 PF01145.20 KND97827.1 - 0.38 10.6 2.7 0.3 10.9 1.0 1.5 2 0 0 2 2 2 0 SPFH domain / Band 7 family Occludin_ELL PF07303.8 KND97827.1 - 1.2 9.9 8.9 6.4 7.5 3.9 2.4 1 1 0 2 2 2 0 Occludin homology domain Phage_GPO PF05929.6 KND97827.1 - 1.8 7.7 6.6 1.4 8.1 3.4 1.7 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Hexokinase_2 PF03727.11 KND97828.1 - 7.8e-95 316.7 0.0 1.1e-94 316.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KND97828.1 - 2.6e-84 281.6 0.0 3.7e-84 281.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase TOM13 PF08219.6 KND97829.1 - 3e-29 100.6 0.2 5.2e-29 99.8 0.1 1.4 1 1 0 1 1 1 1 Outer membrane protein TOM13 Poty_PP PF08440.5 KND97829.1 - 0.11 11.5 0.2 0.13 11.2 0.1 1.1 1 0 0 1 1 1 0 Potyviridae polyprotein Rpr2 PF04032.11 KND97831.1 - 3.9e-24 84.3 1.7 4.9e-24 84.0 1.2 1.1 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Mut7-C PF01927.11 KND97831.1 - 0.032 14.2 0.5 0.039 13.9 0.4 1.1 1 0 0 1 1 1 0 Mut7-C RNAse domain DUF866 PF05907.8 KND97831.1 - 0.038 13.4 0.7 0.047 13.1 0.5 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) zf-DNA_Pol PF08996.5 KND97831.1 - 0.068 12.5 2.3 0.51 9.6 1.5 2.1 1 1 0 1 1 1 0 DNA Polymerase alpha zinc finger Proteasome PF00227.21 KND97832.1 - 2.6e-53 180.1 0.1 3.1e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF3647 PF12363.3 KND97832.1 - 0.034 14.2 0.9 0.27 11.3 0.0 2.2 2 0 0 2 2 2 0 Phage protein XPG_I PF00867.13 KND97833.1 - 4e-26 90.8 0.0 7.2e-26 90.0 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KND97833.1 - 2.1e-25 88.9 0.0 4.5e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 KND97833.1 - 5.1e-08 33.0 0.0 3e-06 27.3 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.1 KND97833.1 - 0.084 13.0 0.2 0.86 9.8 0.0 2.5 3 0 0 3 3 3 0 Helix-hairpin-helix domain HHH_2 PF12826.2 KND97833.1 - 0.11 12.4 0.0 0.42 10.5 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif TniB PF05621.6 KND97833.1 - 0.16 10.7 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Nucleoporin2 PF04096.9 KND97834.1 - 7.1e-49 165.2 0.0 1.1e-48 164.6 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 KND97834.1 - 9.5e-25 87.0 400.6 1.2e-09 38.3 35.5 10.1 1 1 2 5 5 5 3 Nucleoporin FG repeat region AP_endonuc_2 PF01261.19 KND97835.1 - 2e-30 105.6 0.1 3.2e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF692 PF05114.8 KND97835.1 - 0.11 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF692) Telomere_reg-2 PF10193.4 KND97838.1 - 2.4e-34 117.9 0.5 1.2e-33 115.7 0.2 2.4 2 0 0 2 2 2 1 Telomere length regulation protein ABC2_membrane_3 PF12698.2 KND97839.1 - 0.059 12.3 12.0 0.079 11.9 8.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Utp14 PF04615.8 KND97839.1 - 4.1 5.4 15.9 4.6 5.2 11.0 1.1 1 0 0 1 1 1 0 Utp14 protein TFIIA PF03153.8 KND97839.1 - 7.5 6.3 21.6 9.3 6.0 15.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_M28 PF04389.12 KND97840.1 - 8.3e-17 61.4 0.0 1.5e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 KND97840.1 - 1.2e-16 60.4 0.7 2.4e-16 59.4 0.1 1.8 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain PA PF02225.17 KND97840.1 - 8.8e-09 34.9 0.7 3.2e-08 33.1 0.2 2.1 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 KND97840.1 - 0.014 14.9 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Nicastrin PF05450.10 KND97840.1 - 0.018 14.3 0.0 0.042 13.0 0.0 1.6 1 0 0 1 1 1 0 Nicastrin Zn_clus PF00172.13 KND97841.1 - 1.7e-06 27.7 13.0 3.5e-06 26.8 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KND97841.1 - 1.8e-05 23.4 1.8 0.00018 20.2 0.1 2.6 2 1 1 3 3 3 2 Fungal specific transcription factor domain Peptidase_M20 PF01546.23 KND97842.1 - 2e-28 99.1 0.0 2.7e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 KND97842.1 - 6.5e-05 22.7 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.9 KND97842.1 - 0.0011 18.7 0.0 0.0043 16.7 0.0 2.1 1 1 0 1 1 1 1 Peptidase dimerisation domain SEA PF01390.15 KND97842.1 - 0.05 13.3 0.0 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 SEA domain MFS_1 PF07690.11 KND97843.1 - 1.5e-32 112.7 20.0 2.1e-32 112.2 13.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Cytokin_check_N PF10407.4 KND97844.1 - 0.0022 17.5 1.8 0.0054 16.3 0.1 2.3 3 0 0 3 3 3 1 Cdc14 phosphatase binding protein N-terminus TFIIB PF00382.14 KND97845.1 - 1.2e-42 143.5 0.6 6.3e-22 77.1 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 KND97845.1 - 2.2e-13 49.2 1.4 4.2e-13 48.3 1.0 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding FAM180 PF15173.1 KND97845.1 - 0.12 12.1 0.1 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 FAM180 family RB_B PF01857.15 KND97845.1 - 0.12 11.8 0.1 0.28 10.6 0.1 1.6 1 1 0 1 1 1 0 Retinoblastoma-associated protein B domain MFS_1 PF07690.11 KND97846.1 - 2.3e-21 75.9 39.6 8.6e-18 64.1 27.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.8 KND97846.1 - 2.5e-05 22.6 0.7 5.1e-05 21.6 0.5 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector Pox_A14 PF05767.7 KND97846.1 - 3.7 7.5 8.6 0.17 11.8 0.3 2.9 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Candida_ALS_N PF11766.3 KND97848.1 - 7.7e-61 205.1 2.6 2.1e-60 203.7 1.8 1.8 1 0 0 1 1 1 1 Cell-wall agglutinin N-terminal ligand-sugar binding Candida_ALS PF05792.8 KND97848.1 - 3e-10 40.0 29.6 4.9e-08 32.9 10.7 6.4 5 1 0 5 5 5 2 Candida agglutinin-like (ALS) MFS_1 PF07690.11 KND97849.1 - 8.9e-16 57.5 24.4 1.2e-15 57.0 16.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KND97849.1 - 4.1e-06 26.4 2.1 1.3e-05 24.9 1.4 1.9 1 0 0 1 1 1 1 MFS_1 like family WD40 PF00400.27 KND97852.1 - 3.2e-37 125.0 9.6 1.2e-08 34.4 0.0 6.1 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KND97852.1 - 9.1e-08 32.0 3.1 0.031 13.9 0.2 3.0 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Aminotran_1_2 PF00155.16 KND97853.1 - 7.3e-20 71.2 0.0 8.6e-20 70.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KND97853.1 - 0.0023 17.1 0.0 0.0032 16.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase WD40 PF00400.27 KND97854.1 - 1.1e-40 136.0 11.6 7.1e-11 41.5 0.0 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat HIRA_B PF09453.5 KND97854.1 - 3.1e-11 42.5 0.8 7.2e-11 41.3 0.5 1.7 1 0 0 1 1 1 1 HIRA B motif Hira PF07569.6 KND97854.1 - 5.4e-08 32.3 0.0 1e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split PD40 PF07676.7 KND97854.1 - 0.0037 16.8 0.1 33 4.2 0.0 4.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat YmzC PF14157.1 KND97854.1 - 0.042 13.6 0.5 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 YmzC-like protein CHD5 PF04420.9 KND97855.1 - 4.4e-53 179.2 5.3 5.4e-53 178.9 3.7 1.1 1 0 0 1 1 1 1 CHD5-like protein Octopine_DH PF02317.12 KND97855.1 - 0.038 13.6 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain RHD3 PF05879.7 KND97855.1 - 0.077 10.9 1.7 0.097 10.5 1.2 1.0 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) CK_II_beta PF01214.13 KND97856.1 - 1.7e-66 223.2 0.0 2.2e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit HSCB_C PF07743.8 KND97857.1 - 7.9e-15 55.0 2.1 7.9e-15 55.0 1.5 1.8 2 1 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 KND97857.1 - 0.001 18.7 0.1 0.0039 16.8 0.0 2.0 1 1 1 2 2 2 1 DnaJ domain PolyA_pol PF01743.15 KND97857.1 - 0.14 12.3 0.1 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Poly A polymerase head domain Sec23_trunk PF04811.10 KND97860.1 - 8.3e-66 221.8 0.0 1.2e-65 221.3 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 KND97860.1 - 2.3e-31 108.1 0.2 5.1e-31 107.0 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 KND97860.1 - 7.1e-31 105.7 0.1 1.4e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 KND97860.1 - 4.7e-14 51.6 2.7 8.7e-14 50.7 1.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KND97860.1 - 8e-14 51.0 0.0 1.7e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat zf-RanBP PF00641.13 KND97860.1 - 0.0056 15.7 0.1 0.01 14.8 0.1 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others HDA2-3 PF11496.3 KND97863.1 - 5.5e-90 301.1 1.7 1.1e-89 300.1 1.2 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Spc7 PF08317.6 KND97863.1 - 0.0044 15.7 25.3 0.028 13.0 7.9 2.4 1 1 1 2 2 2 2 Spc7 kinetochore protein DUF4200 PF13863.1 KND97863.1 - 0.046 13.6 33.3 0.75 9.7 11.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) COG2 PF06148.6 KND97863.1 - 0.049 13.5 17.4 0.36 10.7 1.5 3.3 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 MerR-DNA-bind PF09278.6 KND97863.1 - 0.13 12.7 8.4 0.94 9.9 0.8 2.8 2 0 0 2 2 2 0 MerR, DNA binding Tropomyosin PF00261.15 KND97863.1 - 0.87 8.6 29.4 5.2 6.0 10.5 2.4 1 1 1 2 2 2 0 Tropomyosin Syntaxin-6_N PF09177.6 KND97863.1 - 1.7 9.1 13.3 1.3 9.4 1.7 2.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF1515 PF07439.6 KND97863.1 - 4.6 7.0 7.9 1.4 8.7 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) TPR_MLP1_2 PF07926.7 KND97863.1 - 6.1 6.6 25.4 1.3 8.7 1.5 3.0 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Adeno_PIX PF03955.9 KND97863.1 - 7.2 7.1 6.2 20 5.7 0.5 2.9 2 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF1664 PF07889.7 KND97863.1 - 8 6.2 14.9 10 5.9 3.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Pox_A_type_inc PF04508.7 KND97863.1 - 9.3 6.3 8.6 0.64 9.9 0.1 3.6 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat WD40 PF00400.27 KND97865.1 - 1.4e-56 186.4 16.9 1.2e-11 43.9 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 KND97865.1 - 4.9e-11 41.6 3.0 7.6e-11 41.0 2.1 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.6 KND97865.1 - 1.5e-06 28.0 0.0 0.0093 15.6 0.0 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A DHFR_2 PF06442.6 KND97865.1 - 0.081 12.5 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 R67 dihydrofolate reductase DUF1373 PF07117.6 KND97865.1 - 0.14 11.9 1.1 1.5 8.4 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1373) 2OG-FeII_Oxy PF03171.15 KND97866.1 - 2e-05 24.8 0.0 5.7e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Peptidase_M16 PF00675.15 KND97867.1 - 7.7e-30 103.6 0.0 1.6e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KND97867.1 - 1.4e-12 47.6 0.3 2.5e-06 27.2 0.0 3.4 4 0 0 4 4 4 2 Peptidase M16 inactive domain Cu_amine_oxid PF01179.15 KND97869.1 - 4.1e-157 523.1 0.3 5e-157 522.8 0.2 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KND97869.1 - 0.016 15.2 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KND97869.1 - 0.019 15.0 0.0 0.055 13.5 0.0 1.8 2 0 0 2 2 2 0 Copper amine oxidase, N2 domain LRR_4 PF12799.2 KND97870.1 - 5e-16 57.9 28.5 2.2e-07 30.3 3.9 5.8 4 1 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KND97870.1 - 1.8e-14 53.2 15.5 2.8e-10 39.8 1.0 4.1 3 1 1 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 KND97870.1 - 3.3e-06 26.3 23.2 0.17 11.9 1.0 6.9 6 1 1 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.1 KND97870.1 - 4.9e-06 26.0 15.7 0.0083 16.0 1.3 5.3 2 2 2 4 4 4 3 Leucine Rich repeat LRR_7 PF13504.1 KND97870.1 - 0.00076 19.2 14.2 1.1 9.7 0.5 6.1 6 0 0 6 6 6 2 Leucine rich repeat LRR_5 PF13306.1 KND97870.1 - 0.0036 16.9 3.7 0.0073 16.0 0.1 2.4 2 1 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KND97870.1 - 0.034 13.7 0.5 0.085 12.4 0.4 1.8 1 0 0 1 1 1 0 Leucine-rich repeat Glyco_hydro_3 PF00933.16 KND97871.1 - 9e-90 300.6 0.0 1.5e-89 299.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KND97871.1 - 2.1e-45 154.9 0.0 5e-45 153.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KND97871.1 - 6.9e-21 73.9 0.0 1.4e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DNA_pol_E_B PF04042.11 KND97873.1 - 9e-39 132.8 0.1 1.3e-38 132.3 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Prenyltrans PF00432.16 KND97874.1 - 5.6e-56 185.7 1.1 7.8e-12 44.5 0.0 5.2 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KND97874.1 - 2.2e-26 92.5 0.0 1.3e-09 38.4 0.0 4.0 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 KND97874.1 - 2.2e-09 37.2 0.0 1.6e-05 24.8 0.0 3.5 2 1 2 4 4 4 3 Prenyltransferase-like Mannosyl_trans3 PF11051.3 KND97875.1 - 1e-68 231.6 2.0 1e-68 231.6 1.4 1.8 2 0 0 2 2 2 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 KND97875.1 - 3.6e-07 29.7 7.2 1.2e-05 24.8 1.8 2.6 1 1 1 2 2 2 2 Glycosyl transferase family 8 Aldolase_II PF00596.16 KND97876.1 - 1.6e-37 128.9 0.0 2e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain AA_permease PF00324.16 KND97877.1 - 3.5e-140 467.5 43.9 4.3e-140 467.2 30.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND97877.1 - 3.9e-42 144.2 46.6 5.4e-42 143.8 32.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KND97878.1 - 1.4e-139 465.5 37.1 1.6e-139 465.3 25.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND97878.1 - 6.2e-43 146.9 40.3 7.7e-43 146.5 28.0 1.1 1 0 0 1 1 1 1 Amino acid permease Nop PF01798.13 KND97880.1 - 3.9e-61 204.7 0.8 1.2e-60 203.1 0.6 1.9 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KND97880.1 - 1.6e-26 91.8 0.0 3.3e-26 90.8 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KND97880.1 - 2.8e-19 69.0 2.5 2.8e-19 69.0 1.8 3.3 2 1 0 2 2 2 1 NOP5NT (NUC127) domain GAGA_bind PF06217.7 KND97880.1 - 2.4 8.0 29.3 0.26 11.1 17.2 1.7 2 0 0 2 2 2 0 GAGA binding protein-like family Dna2 PF08696.6 KND97881.1 - 6.3e-60 202.0 0.0 1.6e-59 200.7 0.0 1.7 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.1 KND97881.1 - 7.5e-50 169.0 0.0 1.8e-49 167.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KND97881.1 - 3.5e-34 118.4 0.3 2.3e-16 60.1 0.0 3.1 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.1 KND97881.1 - 1e-09 38.3 0.0 3.9e-09 36.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND97881.1 - 8.9e-07 28.5 0.0 1.9e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 KND97881.1 - 3.4e-06 26.7 2.0 1.2 8.6 0.0 4.2 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase Cas_Cas4 PF01930.12 KND97881.1 - 6.7e-06 26.1 0.0 0.00014 21.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF83 UvrD-helicase PF00580.16 KND97881.1 - 3.1e-05 23.4 0.7 0.00013 21.4 0.0 2.3 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_18 PF13238.1 KND97881.1 - 0.00025 21.3 0.2 0.17 12.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KND97881.1 - 0.0047 17.4 0.0 0.018 15.5 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein CbiA PF01656.18 KND97881.1 - 0.0079 15.6 0.0 0.023 14.1 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.17 KND97881.1 - 0.0081 15.6 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MobB PF03205.9 KND97881.1 - 0.024 14.3 0.1 0.052 13.2 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SH3_2 PF07653.12 KND97881.1 - 0.06 12.8 0.0 0.34 10.4 0.0 2.2 2 0 0 2 2 2 0 Variant SH3 domain AAA_29 PF13555.1 KND97881.1 - 0.071 12.6 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 KND97881.1 - 0.077 12.7 0.1 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sars6 PF12133.3 KND97881.1 - 0.098 12.3 0.0 0.3 10.8 0.0 1.8 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus Helicase_RecD PF05127.9 KND97881.1 - 0.11 12.0 0.0 0.35 10.4 0.0 1.8 1 1 0 1 1 1 0 Helicase Sel1 PF08238.7 KND97882.1 - 6.5e-24 83.8 15.0 0.0011 19.5 0.0 8.3 8 0 0 8 8 8 6 Sel1 repeat TPR_11 PF13414.1 KND97882.1 - 0.0032 17.0 5.3 0.036 13.7 0.1 4.5 4 0 0 4 4 4 1 TPR repeat Sec61_beta PF03911.11 KND97882.1 - 0.041 13.6 0.1 0.072 12.9 0.1 1.4 1 0 0 1 1 1 0 Sec61beta family TPR_1 PF00515.23 KND97882.1 - 0.11 12.2 0.2 0.11 12.2 0.1 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 KND97882.1 - 0.11 13.2 3.7 0.25 12.0 0.0 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 KND97882.1 - 0.16 11.8 1.0 1.4 8.8 0.1 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain V_ATPase_I PF01496.14 KND97883.1 - 3.6e-260 865.0 17.4 4.3e-201 669.6 11.1 2.0 2 0 0 2 2 2 2 V-type ATPase 116kDa subunit family DUF3585 PF12130.3 KND97885.1 - 0.23 11.3 4.4 3.8 7.3 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3585) SurE PF01975.12 KND97889.1 - 1.5e-44 151.6 0.0 2.3e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Peroxin-3 PF04882.7 KND97890.1 - 3.8e-106 355.4 8.9 5.3e-106 354.9 6.2 1.2 1 0 0 1 1 1 1 Peroxin-3 Skp1 PF01466.14 KND97891.1 - 3.4e-35 119.9 0.5 5.7e-35 119.1 0.3 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KND97891.1 - 4.6e-21 74.6 0.6 9.9e-21 73.6 0.4 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Sds3 PF08598.6 KND97892.1 - 0.014 14.9 8.0 0.016 14.7 5.2 1.6 1 1 0 1 1 1 0 Sds3-like Thioredoxin_7 PF13899.1 KND97893.1 - 8.9e-19 67.3 0.0 1.9e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 KND97893.1 - 2.6e-10 39.6 0.4 4.7e-10 38.8 0.3 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 KND97893.1 - 6.3e-10 38.9 0.0 1.3e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.10 KND97893.1 - 0.0055 16.4 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Nop14 PF04147.7 KND97893.1 - 0.1 10.4 8.2 0.17 9.7 5.7 1.3 1 0 0 1 1 1 0 Nop14-like family Thioredoxin_2 PF13098.1 KND97893.1 - 0.11 12.6 0.1 0.52 10.5 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain Pkinase PF00069.20 KND97895.1 - 2e-49 168.1 0.0 5.8e-49 166.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND97895.1 - 3.1e-24 85.4 0.0 1.2e-23 83.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KND97895.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Fungal_trans PF04082.13 KND97896.1 - 9.2e-14 50.9 0.7 1.4e-13 50.2 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1479 PF07350.7 KND97897.1 - 7.6e-148 492.4 0.0 1e-147 492.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 KND97897.1 - 0.0011 19.0 0.2 0.031 14.3 0.2 2.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Epimerase PF01370.16 KND97898.1 - 2.6e-17 63.0 0.0 4.2e-17 62.3 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KND97898.1 - 4.4e-15 55.1 0.0 6.1e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KND97898.1 - 1.7e-12 46.7 0.0 1e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KND97898.1 - 8e-11 42.2 0.0 1.3e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KND97898.1 - 0.0002 20.3 0.1 0.00044 19.2 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KND97898.1 - 0.00033 20.5 0.0 0.00062 19.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 KND97898.1 - 0.0004 19.7 0.1 0.00097 18.4 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family F420_oxidored PF03807.12 KND97898.1 - 0.0092 16.3 0.0 0.028 14.8 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 KND97898.1 - 0.017 14.7 0.0 0.044 13.4 0.0 1.6 1 1 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.19 KND97898.1 - 0.03 14.6 0.1 0.17 12.2 0.0 2.1 2 1 1 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 KND97898.1 - 0.058 12.2 0.1 0.59 8.9 0.0 2.3 1 1 0 2 2 2 0 RmlD substrate binding domain Circo_capsid PF02443.10 KND97898.1 - 0.067 12.5 0.2 0.096 12.0 0.1 1.1 1 0 0 1 1 1 0 Circovirus capsid protein ELFV_dehydrog PF00208.16 KND97898.1 - 0.074 12.6 0.2 0.34 10.4 0.1 2.2 2 1 1 3 3 3 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DapB_N PF01113.15 KND97898.1 - 0.1 12.5 0.1 0.38 10.6 0.0 2.1 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus WD40 PF00400.27 KND97899.1 - 4.4e-22 77.0 16.2 3.3e-07 29.9 0.0 10.4 10 0 0 10 10 10 6 WD domain, G-beta repeat CPSF_A PF03178.10 KND97899.1 - 1.9e-05 23.9 0.1 0.00023 20.3 0.0 2.5 2 0 0 2 2 2 1 CPSF A subunit region Nup160 PF11715.3 KND97899.1 - 0.0053 14.9 0.2 0.43 8.6 0.1 2.4 2 0 0 2 2 2 2 Nucleoporin Nup120/160 tRNA-synt_1 PF00133.17 KND97900.1 - 1.1e-229 763.4 0.3 3.6e-229 761.7 0.1 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KND97900.1 - 3.3e-27 95.1 0.0 7.5e-27 93.9 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KND97900.1 - 5.1e-19 68.1 1.7 2.1e-07 29.9 0.1 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KND97900.1 - 0.003 16.8 0.3 0.064 12.5 0.1 2.3 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 KND97900.1 - 0.01 15.0 0.0 0.056 12.5 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain ATP_bind_3 PF01171.15 KND97901.1 - 3.8e-46 156.8 0.0 6.2e-46 156.1 0.0 1.3 1 0 0 1 1 1 1 PP-loop family Asn_synthase PF00733.16 KND97901.1 - 3.3e-06 26.8 0.0 6.1e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 KND97901.1 - 0.027 13.0 0.0 0.046 12.2 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase Peptidase_M1 PF01433.15 KND97902.1 - 1.1e-09 37.9 0.0 0.029 13.4 0.0 3.3 3 0 0 3 3 3 3 Peptidase family M1 HEAT_2 PF13646.1 KND97902.1 - 0.005 17.0 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 HEAT repeats VPS9 PF02204.13 KND97903.1 - 1.6e-31 108.3 0.5 3.3e-31 107.4 0.4 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 KND97903.1 - 4.4e-05 22.8 2.1 5.2e-05 22.6 0.1 2.3 3 0 0 3 3 3 1 CUE domain EutQ PF06249.7 KND97904.1 - 4e-09 36.1 0.0 4.7e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 KND97904.1 - 4.1e-09 35.6 0.1 6.1e-09 35.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 KND97904.1 - 1.1e-06 28.0 0.1 1.5e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 KND97904.1 - 0.0028 17.3 0.0 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_1 PF00190.17 KND97904.1 - 0.011 15.2 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 0 Cupin ARD PF03079.9 KND97904.1 - 0.051 13.5 0.1 0.068 13.1 0.0 1.1 1 0 0 1 1 1 0 ARD/ARD' family Pirin PF02678.11 KND97904.1 - 0.062 13.1 0.0 0.072 12.9 0.0 1.2 1 0 0 1 1 1 0 Pirin CDC37_N PF03234.9 KND97905.1 - 8.1e-59 198.9 13.6 8.1e-59 198.9 9.4 2.7 3 1 1 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 KND97905.1 - 2.2e-45 154.2 4.5 2.2e-45 154.2 3.1 1.9 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 KND97905.1 - 2.6e-19 68.9 2.4 2.6e-19 68.9 1.6 2.5 3 0 0 3 3 3 1 Cdc37 C terminal domain DUF4315 PF14193.1 KND97905.1 - 0.22 11.4 5.8 8.6 6.3 0.4 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) RRM_1 PF00076.17 KND97906.1 - 3.1e-10 39.5 0.0 6.1e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND97906.1 - 4.5e-07 29.7 0.0 8.9e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND97906.1 - 0.004 16.9 0.0 0.0078 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF607 PF04678.8 KND97906.1 - 0.12 12.2 0.2 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF607 GFO_IDH_MocA PF01408.17 KND97907.1 - 9.2e-22 77.8 0.2 6.8e-21 75.0 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KND97907.1 - 2.2e-06 27.4 0.0 9.9e-06 25.3 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Hpr_kinase_N PF02603.11 KND97907.1 - 0.046 13.4 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase N terminus Sec20 PF03908.8 KND97908.1 - 3.4e-26 90.7 1.8 3.4e-26 90.7 1.2 3.7 3 2 1 4 4 4 1 Sec20 Exo_endo_phos PF03372.18 KND97909.1 - 2.7e-24 86.4 0.4 3.6e-24 86.0 0.3 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Mob1_phocein PF03637.12 KND97910.1 - 1.6e-69 233.0 0.5 1.9e-69 232.8 0.3 1.1 1 0 0 1 1 1 1 Mob1/phocein family DDE_Tnp_1_6 PF13751.1 KND97912.1 - 0.024 14.6 0.3 0.03 14.3 0.2 1.2 1 0 0 1 1 1 0 Transposase DDE domain Thioredoxin PF00085.15 KND97916.1 - 0.041 13.5 0.1 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DNA_pack_N PF02500.10 KND97916.1 - 0.1 12.1 0.2 0.12 11.8 0.2 1.0 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus Sod_Cu PF00080.15 KND97917.1 - 7.3e-19 68.3 0.1 1.6e-18 67.2 0.0 1.5 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Fe-S_biosyn PF01521.15 KND97918.1 - 8.5e-19 67.5 0.0 1.3e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Mitofilin PF09731.4 KND97918.1 - 0.097 11.3 12.6 0.12 10.9 8.8 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ebola_NP PF05505.7 KND97918.1 - 0.51 8.3 4.9 0.66 7.9 3.4 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein TFIIA PF03153.8 KND97918.1 - 1.3 8.8 8.1 1.6 8.5 5.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S30 PF01577.11 KND97918.1 - 3.5 6.9 8.7 6.4 6.0 5.9 1.5 2 0 0 2 2 2 0 Potyvirus P1 protease Peptidase_M24 PF00557.19 KND97919.1 - 6.4e-34 117.3 0.0 9.4e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KND97919.1 - 3.6e-15 56.6 0.0 1.4e-10 41.7 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Rep_fac-A_C PF08646.5 KND97923.1 - 6.3e-53 178.3 3.7 8e-50 168.3 0.8 3.2 3 0 0 3 3 3 2 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 KND97923.1 - 1.1e-16 60.4 0.2 3.6e-10 39.5 0.0 4.3 4 1 1 5 5 5 3 OB-fold nucleic acid binding domain Rep-A_N PF04057.7 KND97923.1 - 1.1e-11 44.3 0.0 4.2e-11 42.5 0.0 1.9 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain Cys_Met_Meta_PP PF01053.15 KND97924.1 - 2.9e-133 443.9 0.0 3.4e-133 443.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KND97924.1 - 4.6e-06 25.9 0.0 7.2e-05 21.9 0.0 2.4 2 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 KND97924.1 - 3.2e-05 23.0 0.0 5.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KND97924.1 - 0.0039 16.0 0.0 0.0075 15.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KND97924.1 - 0.017 14.2 0.0 0.048 12.7 0.0 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase 2Fe-2S_thioredx PF01257.14 KND97925.1 - 5e-61 204.5 0.3 6.1e-61 204.2 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Transp_cyt_pur PF02133.10 KND97926.1 - 1.7e-52 178.4 28.8 2.1e-52 178.1 19.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4149 PF13664.1 KND97926.1 - 2.4 8.2 12.0 0.11 12.5 1.3 3.2 2 2 1 3 3 3 0 Domain of unknown function (DUF4149) DUF2348 PF09807.4 KND97927.1 - 0.0035 16.4 0.1 0.007 15.4 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) TrbI_Ftype PF09677.5 KND97927.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) DUF3336 PF11815.3 KND97928.1 - 1.2e-37 128.6 5.1 2.2e-37 127.7 3.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KND97928.1 - 5.4e-07 29.7 0.1 1.4e-06 28.3 0.1 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase MFS_1 PF07690.11 KND97929.1 - 2.5e-25 88.9 34.8 2.2e-15 56.2 9.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 KND97929.1 - 3.5e-06 25.7 12.5 3.5e-06 25.7 8.7 2.7 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_3 PF05977.8 KND97929.1 - 2.4 6.1 11.2 0.058 11.5 0.5 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector UTP15_C PF09384.5 KND97930.1 - 6.6e-44 149.1 0.0 9.8e-44 148.6 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 KND97930.1 - 1.7e-16 59.4 5.7 1.7e-05 24.4 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 KND97930.1 - 0.0011 18.7 0.0 0.47 10.2 0.0 3.3 1 1 3 4 4 4 3 Ciliary BBSome complex subunit 2, middle region PHD PF00628.24 KND97931.1 - 3.9e-07 29.6 6.5 8.9e-07 28.5 4.5 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 KND97931.1 - 0.0081 16.2 1.4 0.021 14.9 1.0 1.8 1 1 0 1 1 1 1 PHD-like zinc-binding domain AT_hook PF02178.14 KND97931.1 - 1.5 8.7 9.4 0.069 12.8 1.4 2.6 2 0 0 2 2 2 0 AT hook motif Ribosomal_L3 PF00297.17 KND97932.1 - 8.1e-117 389.2 10.2 9.7e-117 389.0 7.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 IL6Ra-bind PF09240.5 KND97933.1 - 0.022 14.9 1.6 0.028 14.5 0.4 1.7 1 1 0 1 1 1 0 Interleukin-6 receptor alpha chain, binding NmrA PF05368.8 KND97934.1 - 1e-07 31.4 0.1 1.7e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KND97934.1 - 4.6e-05 23.5 0.2 0.00012 22.1 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 KND97934.1 - 0.00021 20.1 0.0 0.00032 19.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KND97934.1 - 0.0042 16.5 0.0 0.0076 15.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family MalF_P2 PF14785.1 KND97935.1 - 0.031 14.1 1.6 0.1 12.4 0.0 2.4 3 0 0 3 3 3 0 Maltose transport system permease protein MalF P2 domain AT_hook PF02178.14 KND97935.1 - 0.077 12.7 5.5 0.26 11.1 3.8 2.0 1 0 0 1 1 1 0 AT hook motif ERG4_ERG24 PF01222.12 KND97936.1 - 6.8e-148 492.7 13.5 7.7e-148 492.5 9.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KND97936.1 - 2e-08 33.8 2.3 2e-08 33.8 1.6 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1295) ATP-synt_S1 PF05827.7 KND97937.1 - 1.8e-12 47.1 0.1 2.4e-12 46.7 0.1 1.4 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) FKBP_N PF01346.13 KND97937.1 - 0.044 13.8 0.5 0.12 12.4 0.4 1.6 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase VMA21 PF09446.5 KND97938.1 - 7.4e-08 32.2 6.1 1.1e-07 31.7 4.3 1.2 1 0 0 1 1 1 1 VMA21-like domain RseC_MucC PF04246.7 KND97938.1 - 0.047 13.2 0.0 0.047 13.2 0.0 1.0 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Med18 PF09637.5 KND97939.1 - 9.2e-81 271.0 1.7 1.1e-80 270.8 1.2 1.0 1 0 0 1 1 1 1 Med18 protein Herpes_BLRF2 PF05812.7 KND97940.1 - 0.0065 16.2 0.4 0.015 15.0 0.1 1.7 2 0 0 2 2 2 1 Herpesvirus BLRF2 protein Baculo_gp41 PF04700.7 KND97940.1 - 0.068 12.5 0.1 0.11 11.9 0.0 1.4 2 0 0 2 2 2 0 Structural glycoprotein p40/gp41 conserved region RecX PF02631.11 KND97940.1 - 0.15 12.3 0.5 1.2 9.3 0.1 2.4 2 1 0 2 2 2 0 RecX family Pescadillo_N PF06732.6 KND97941.1 - 1.4e-116 388.6 0.4 1.4e-116 388.6 0.3 2.1 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 KND97941.1 - 9e-08 32.1 0.0 2.9e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Acyltransferase PF01553.16 KND97942.1 - 1e-09 37.9 0.0 6.4e-09 35.3 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase PPR_2 PF13041.1 KND97943.1 - 0.00098 19.0 1.0 33 4.5 0.0 5.0 5 0 0 5 5 5 1 PPR repeat family PPR_3 PF13812.1 KND97943.1 - 0.0032 17.6 0.3 84 3.8 0.0 5.3 5 0 0 5 5 5 0 Pentatricopeptide repeat domain PPR PF01535.15 KND97943.1 - 0.028 14.3 0.7 77 3.5 0.0 4.9 5 0 0 5 5 5 0 PPR repeat Kinesin PF00225.18 KND97944.1 - 1.3e-97 326.4 2.5 1.3e-97 326.4 1.7 2.4 2 0 0 2 2 2 1 Kinesin motor domain DUF3244 PF11589.3 KND97944.1 - 0.062 13.0 2.3 0.22 11.2 1.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3244) Rrp15p PF07890.7 KND97945.1 - 1.1e-34 119.2 14.0 1.1e-34 119.2 9.7 1.9 2 1 0 2 2 2 1 Rrp15p RRS1 PF04939.7 KND97945.1 - 0.025 14.0 0.2 0.025 14.0 0.2 2.7 2 1 1 3 3 3 0 Ribosome biogenesis regulatory protein (RRS1) RelA_SpoT PF04607.12 KND97945.1 - 0.13 12.2 1.4 0.26 11.3 0.9 1.5 1 0 0 1 1 1 0 Region found in RelA / SpoT proteins CDC45 PF02724.9 KND97945.1 - 0.45 8.4 14.7 0.74 7.7 10.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 KND97945.1 - 0.97 7.8 18.5 1.3 7.4 12.8 1.1 1 0 0 1 1 1 0 Daxx Family MFS_1 PF07690.11 KND97946.1 - 3.2e-29 101.7 24.4 6e-24 84.4 7.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KND97946.1 - 0.16 12.0 4.9 0.47 10.5 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) SGS PF05002.10 KND97947.1 - 1.2e-25 89.0 3.2 1.2e-25 89.0 2.2 2.2 2 1 0 2 2 2 1 SGS domain CS PF04969.11 KND97947.1 - 1.6e-22 79.7 2.3 3.5e-22 78.7 1.2 1.9 2 0 0 2 2 2 1 CS domain TPR_11 PF13414.1 KND97947.1 - 1e-10 41.0 7.0 3.6e-08 32.9 2.0 2.3 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.1 KND97947.1 - 4.2e-05 24.0 3.6 0.00027 21.4 0.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KND97947.1 - 4.6e-05 23.0 9.9 0.36 10.8 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KND97947.1 - 0.00041 19.8 11.7 0.77 9.4 0.6 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KND97947.1 - 0.00089 19.1 3.6 0.0011 18.8 0.8 2.2 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KND97947.1 - 0.048 14.0 2.1 0.43 10.9 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KND97947.1 - 0.087 13.5 1.4 6 7.7 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KND97947.1 - 0.11 12.2 7.5 4.5 7.2 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KND97947.1 - 0.23 12.0 2.6 42 4.9 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4398 PF14346.1 KND97949.1 - 0.76 9.8 9.6 1.7 8.7 6.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) SRP9-21 PF05486.7 KND97950.1 - 4.2e-21 74.4 1.4 6.2e-21 73.9 1.0 1.3 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) DNA_pol3_delta PF06144.8 KND97950.1 - 0.0075 15.7 1.5 0.011 15.2 1.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Nramp PF01566.13 KND97952.1 - 2.6e-87 292.9 16.0 5e-87 292.0 8.7 2.4 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein Biotin_lipoyl PF00364.17 KND97953.1 - 4.4e-19 67.8 0.8 7.8e-19 67.0 0.6 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KND97953.1 - 1.3e-05 24.7 0.4 4.2e-05 23.0 0.1 2.1 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 KND97953.1 - 0.0059 16.2 0.1 0.027 14.1 0.0 2.0 2 0 0 2 2 2 1 Biotin-lipoyl like AT_hook PF02178.14 KND97954.1 - 0.0024 17.3 22.2 0.0068 15.9 0.6 3.5 3 0 0 3 3 3 3 AT hook motif zf-TFIIIC PF12660.2 KND97957.1 - 9e-06 25.5 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.2 KND97957.1 - 1.7e-05 24.6 0.0 0.00014 21.6 0.0 2.3 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term PALP PF00291.20 KND97960.1 - 2.2e-57 194.6 0.4 2.6e-57 194.3 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Radical_SAM PF04055.16 KND97960.1 - 0.05 13.7 0.0 0.3 11.2 0.0 2.1 2 1 0 2 2 2 0 Radical SAM superfamily 2OG-FeII_Oxy_3 PF13640.1 KND97961.1 - 3.5e-10 40.3 0.1 5e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KND97961.1 - 2.7e-05 23.7 0.4 7.4e-05 22.3 0.3 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KND97961.1 - 0.00026 21.2 0.0 0.00047 20.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HTH_WhiA PF02650.9 KND97961.1 - 0.11 12.8 0.1 0.22 11.9 0.1 1.5 1 0 0 1 1 1 0 WhiA C-terminal HTH domain Nic96 PF04097.9 KND97962.1 - 5.2e-191 635.9 7.7 7.3e-191 635.4 5.3 1.2 1 0 0 1 1 1 1 Nup93/Nic96 AA_permease_2 PF13520.1 KND97963.1 - 8.4e-50 169.5 55.0 1e-49 169.2 38.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KND97963.1 - 6.9e-18 64.2 47.2 9.1e-18 63.8 32.7 1.0 1 0 0 1 1 1 1 Amino acid permease LNS2 PF08235.8 KND97964.1 - 1.8e-74 248.5 0.0 3.4e-74 247.6 0.0 1.5 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 KND97964.1 - 1.1e-36 124.8 0.0 2.6e-36 123.6 0.0 1.7 1 0 0 1 1 1 1 lipin, N-terminal conserved region Hydrolase_6 PF13344.1 KND97964.1 - 0.0034 17.2 0.0 0.013 15.4 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Nop14 PF04147.7 KND97964.1 - 0.86 7.4 34.5 1.6 6.5 23.9 1.4 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KND97964.1 - 1.5 7.1 30.3 2.6 6.4 21.0 1.3 1 0 0 1 1 1 0 Daxx Family DUF3589 PF12141.3 KND97965.1 - 1.4e-157 524.8 0.0 1.8e-157 524.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3589) RRM_1 PF00076.17 KND97966.1 - 7.2e-21 73.6 0.1 5.2e-14 51.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND97966.1 - 7.8e-18 64.2 0.0 6.4e-11 42.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND97966.1 - 1.9e-16 59.6 0.0 3.9e-10 39.4 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KND97966.1 - 7.1e-06 25.8 0.3 0.0047 16.7 0.0 2.1 1 1 1 2 2 2 2 RNA binding motif Calcipressin PF04847.7 KND97966.1 - 0.0036 16.9 0.0 0.0061 16.1 0.0 1.4 1 0 0 1 1 1 1 Calcipressin Limkain-b1 PF11608.3 KND97966.1 - 0.033 13.9 0.2 0.067 12.9 0.0 1.6 2 0 0 2 2 2 0 Limkain b1 Abhydrolase_3 PF07859.8 KND97967.1 - 5e-11 42.5 0.0 5e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KND97967.1 - 3e-08 33.5 0.0 3.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND97967.1 - 0.00032 20.6 0.0 0.00061 19.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KND97967.1 - 0.0019 16.8 0.0 0.0032 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) AhpC-TSA PF00578.16 KND97967.1 - 0.021 14.4 0.0 0.21 11.2 0.0 2.2 2 0 0 2 2 2 0 AhpC/TSA family DUF915 PF06028.6 KND97967.1 - 0.022 13.8 0.0 0.08 12.0 0.0 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF2305 PF10230.4 KND97967.1 - 0.025 13.9 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_1 PF00561.15 KND97967.1 - 0.14 11.6 0.0 1.1 8.7 0.0 2.2 3 0 0 3 3 3 0 alpha/beta hydrolase fold eIF3g PF12353.3 KND97968.1 - 4.8e-46 155.8 2.7 6.9e-46 155.3 1.9 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 KND97968.1 - 1.3e-14 53.5 0.0 2.1e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND97968.1 - 3.5e-10 39.7 0.0 6.5e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND97968.1 - 4.6e-07 29.5 0.0 8.7e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2782 PF11191.3 KND97968.1 - 0.049 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) WD40 PF00400.27 KND97969.1 - 2.5e-32 109.5 14.5 6.1e-10 38.5 0.0 7.5 6 1 0 6 6 6 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KND97969.1 - 0.043 12.1 0.3 2.6 6.2 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF1149 PF06619.6 KND97969.1 - 0.05 13.5 0.3 5.3 6.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1149) STAG PF08514.6 KND97970.1 - 2.9e-19 68.9 2.4 8.1e-19 67.4 0.6 2.6 3 0 0 3 3 3 1 STAG domain HEAT PF02985.17 KND97970.1 - 0.058 13.5 0.2 1.3 9.2 0.0 3.5 4 0 0 4 4 4 0 HEAT repeat SWIRM PF04433.12 KND97971.1 - 5.5e-33 112.9 1.5 1.3e-32 111.7 0.1 2.4 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 KND97971.1 - 7.6e-06 25.8 0.1 1.7e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KND97971.1 - 0.00045 20.2 0.1 0.00045 20.2 0.1 3.3 2 1 0 2 2 2 1 Myb-like DNA-binding domain HTH_Tnp_IS630 PF01710.11 KND97971.1 - 0.024 14.3 0.8 1.2 8.8 0.0 2.6 2 0 0 2 2 2 0 Transposase Myb_DNA-bind_4 PF13837.1 KND97971.1 - 0.026 14.6 0.1 0.093 12.8 0.1 2.0 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain PolyA_pol PF01743.15 KND97971.1 - 0.083 13.1 0.5 0.37 11.0 0.0 2.3 2 0 0 2 2 2 0 Poly A polymerase head domain tRNA_Me_trans PF03054.11 KND97972.1 - 1.4e-117 392.2 0.0 1.6e-117 392.0 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.16 KND97972.1 - 0.00019 21.0 0.0 0.00028 20.4 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 KND97972.1 - 0.0017 17.3 0.0 0.0081 15.0 0.0 1.9 2 0 0 2 2 2 1 NAD synthase ATP_bind_3 PF01171.15 KND97972.1 - 0.0083 15.6 0.1 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 PP-loop family zf-C2H2 PF00096.21 KND97973.1 - 2.4e-07 30.7 14.8 2.6e-05 24.2 2.4 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KND97973.1 - 0.00057 20.0 2.3 0.00057 20.0 1.6 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KND97973.1 - 0.00099 19.2 13.6 0.0073 16.5 1.2 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 KND97973.1 - 0.055 13.7 1.1 0.055 13.7 0.8 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF4570 PF15134.1 KND97973.1 - 9.9 6.0 11.0 0.17 11.7 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) LtrA PF06772.6 KND97974.1 - 4e-21 75.3 14.2 6.1e-21 74.7 9.8 1.3 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) AATase PF07247.7 KND97975.1 - 1.7e-66 224.7 0.9 2.1e-66 224.4 0.6 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 KND97975.1 - 2.8e-06 26.4 0.1 5.5e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Condensation domain B_lectin PF01453.19 KND97976.1 - 0.035 13.9 0.0 0.039 13.8 0.0 1.0 1 0 0 1 1 1 0 D-mannose binding lectin CD99L2 PF12301.3 KND97977.1 - 0.2 11.3 2.8 0.19 11.3 0.9 1.8 1 1 0 1 1 1 0 CD99 antigen like protein 2 CAS_CSE1 PF03378.10 KND97978.1 - 0.26 9.5 2.7 0.28 9.4 1.9 1.0 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus CENP-O PF09496.5 KND97983.1 - 4.5e-16 58.8 0.2 8e-16 58.0 0.1 1.4 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component Clathrin PF00637.15 KND97984.1 - 4.1e-188 616.4 57.3 1.5e-32 112.1 0.7 8.1 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 KND97984.1 - 6e-26 90.1 0.5 6e-26 90.1 0.4 2.1 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 KND97984.1 - 6.4e-19 66.8 1.9 0.1 12.9 0.0 6.8 6 0 0 6 6 6 6 Clathrin propeller repeat TPR_2 PF07719.12 KND97984.1 - 6.3e-05 22.5 2.8 12 6.1 0.1 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat Clathrin-link PF09268.5 KND97984.1 - 0.00051 19.0 0.0 0.0016 17.4 0.0 2.0 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_1 PF00515.23 KND97984.1 - 0.00085 18.8 11.5 8.9 6.1 0.1 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KND97984.1 - 0.002 17.8 9.4 21 5.2 0.0 8.1 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_19 PF14559.1 KND97984.1 - 0.0024 18.1 2.7 86 3.5 0.0 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_12 PF13424.1 KND97984.1 - 0.014 15.2 7.5 11 6.0 0.2 7.0 8 1 0 8 8 8 0 Tetratricopeptide repeat PPR PF01535.15 KND97984.1 - 0.07 13.1 3.6 45 4.3 0.0 5.9 6 0 0 6 6 5 0 PPR repeat TPR_17 PF13431.1 KND97984.1 - 0.095 12.9 1.5 4 7.8 0.0 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 KND97987.1 - 6.7e-24 85.0 0.0 8e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND97987.1 - 1.8e-09 37.4 0.0 2.4e-09 37.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KND97987.1 - 8.9e-08 32.6 0.0 1.1e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 KND97987.1 - 2.3e-05 24.0 0.0 6.8e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KND97987.1 - 0.0003 20.4 0.0 0.00049 19.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 KND97987.1 - 0.009 15.8 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 KND97987.1 - 0.032 12.7 0.0 0.048 12.1 0.0 1.3 1 0 0 1 1 1 0 Ndr family DUF2920 PF11144.3 KND97987.1 - 0.069 12.1 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) CBFD_NFYB_HMF PF00808.18 KND97988.1 - 3.7e-14 52.5 3.4 6.6e-14 51.7 2.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 KND97988.1 - 0.03 14.5 0.3 0.14 12.3 0.2 1.9 1 1 1 2 2 2 0 Kinetochore component CENP-S Bromo_TP PF07524.8 KND97988.1 - 0.043 13.5 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 KND97988.1 - 0.11 12.5 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF3753 PF12575.3 KND97988.1 - 0.12 12.1 0.3 0.31 10.8 0.1 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF3753) Orthopox_B11R PF07033.6 KND97988.1 - 0.5 9.8 3.9 0.18 11.2 0.4 2.1 2 1 0 2 2 2 0 Orthopoxvirus B11R protein BRX_N PF13713.1 KND97988.1 - 6.1 6.3 7.6 2.2 7.7 0.1 2.8 3 0 0 3 3 3 0 Transcription factor BRX N-terminal domain Yos1 PF08571.5 KND97989.1 - 2e-31 107.8 1.1 2.3e-31 107.7 0.8 1.0 1 0 0 1 1 1 1 Yos1-like Cse1 PF08506.5 KND97990.1 - 1.1e-11 43.8 3.6 1.1e-11 43.8 2.5 3.8 2 2 1 3 3 3 1 Cse1 IBN_N PF03810.14 KND97990.1 - 1.1e-10 41.2 0.2 4.5e-10 39.3 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Symplekin_C PF12295.3 KND97990.1 - 0.49 10.2 11.2 0.036 13.9 1.6 3.4 3 2 1 4 4 4 0 Symplekin tight junction protein C terminal UFD1 PF03152.9 KND97991.1 - 3.9e-73 244.3 0.0 5e-73 243.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF3290 PF11694.3 KND97991.1 - 0.18 11.5 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Pribosyltran PF00156.22 KND97992.1 - 1.9e-11 43.7 0.9 6.7e-11 42.0 0.1 2.1 1 1 1 2 2 2 1 Phosphoribosyl transferase domain Fe-ADH PF00465.14 KND97992.1 - 0.016 13.9 0.0 0.024 13.2 0.0 1.3 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Mito_fiss_Elm1 PF06258.6 KND97992.1 - 0.083 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission ELM1 DUF2141 PF09912.4 KND97992.1 - 0.13 11.9 0.1 0.26 10.9 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2141) HSP70 PF00012.15 KND97994.1 - 1e-47 162.3 6.7 1e-47 162.3 4.6 2.9 1 1 2 3 3 3 1 Hsp70 protein FGGY_C PF02782.11 KND97994.1 - 0.031 13.8 0.3 0.28 10.7 0.0 2.5 3 0 0 3 3 3 0 FGGY family of carbohydrate kinases, C-terminal domain Phage_P2_GpE PF06528.7 KND97994.1 - 0.2 11.0 0.1 0.38 10.2 0.0 1.5 1 0 0 1 1 1 0 Phage P2 GpE RRM_1 PF00076.17 KND97995.1 - 3.3e-11 42.6 0.0 0.0094 15.5 0.0 4.3 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND97995.1 - 1.9e-10 40.5 0.0 0.0011 18.9 0.0 3.6 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND97995.1 - 0.00022 20.9 0.0 0.01 15.7 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RabGAP-TBC PF00566.13 KND97996.1 - 4.1e-39 134.2 0.0 5.9e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RRP7 PF12923.2 KND97997.1 - 1.4e-35 122.2 11.7 2.1e-35 121.5 8.1 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) FeoC PF09012.5 KND97997.1 - 0.088 12.5 0.7 0.19 11.4 0.2 1.8 2 0 0 2 2 2 0 FeoC like transcriptional regulator RRM_1 PF00076.17 KND97997.1 - 0.25 11.0 2.7 15 5.3 0.0 2.9 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF45 PF01863.12 KND97997.1 - 0.84 9.3 4.2 1.3 8.8 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 Aminotran_4 PF01063.14 KND97998.1 - 1.2e-25 90.3 0.1 4.1e-25 88.5 0.1 1.9 1 1 0 1 1 1 1 Aminotransferase class IV HAD PF12710.2 KND97999.1 - 5.1e-15 56.1 0.1 8.2e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KND97999.1 - 1.4e-12 47.7 0.6 7.6e-10 38.7 0.0 3.3 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KND97999.1 - 1.5e-10 41.8 0.1 7.3e-09 36.3 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KND97999.1 - 2.8e-05 24.4 0.0 0.00016 21.9 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase S6PP PF05116.8 KND97999.1 - 0.043 13.1 2.8 0.51 9.5 0.0 2.8 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase CRAL_TRIO PF00650.15 KND98000.1 - 4e-36 123.8 0.0 6.3e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KND98000.1 - 3.4e-15 55.9 0.4 8.1e-15 54.7 0.3 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF1912 PF08930.5 KND98000.1 - 0.037 14.1 0.1 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) NNMT_PNMT_TEMT PF01234.12 KND98000.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family CENP-Q PF13094.1 KND98001.1 - 1.7e-14 54.1 7.6 2.9e-14 53.4 5.2 1.4 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Gam PF06064.6 KND98001.1 - 0.054 13.6 0.2 0.24 11.5 0.1 2.1 1 1 1 2 2 2 0 Host-nuclease inhibitor protein Gam SRA1 PF07304.6 KND98001.1 - 0.064 12.9 0.1 0.15 11.8 0.0 1.7 1 1 0 1 1 1 0 Steroid receptor RNA activator (SRA1) IncA PF04156.9 KND98001.1 - 1.2 8.7 12.0 3.7 7.0 7.5 2.0 1 1 0 1 1 1 0 IncA protein RRN7 PF11781.3 KND98002.1 - 5.2e-10 38.6 0.3 1.2e-09 37.4 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 Aldedh PF00171.17 KND98003.1 - 6e-181 601.8 0.5 6.8e-181 601.6 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KND98003.1 - 0.0014 17.4 0.0 0.0034 16.1 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KND98003.1 - 0.019 14.2 0.1 0.087 12.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Big_1 PF02369.11 KND98003.1 - 0.065 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) Ribosomal_S24e PF01282.14 KND98004.1 - 1.4e-34 117.6 0.0 2.2e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e SeleniumBinding PF11524.3 KND98004.1 - 0.05 13.7 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 Selenium binding protein IPK PF03770.11 KND98005.1 - 1.9e-46 158.2 0.0 2.7e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF1645 PF07816.6 KND98005.1 - 0.016 15.7 0.7 0.016 15.7 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) FAM194 PF14977.1 KND98006.1 - 0.004 16.1 0.2 0.0051 15.8 0.1 1.1 1 0 0 1 1 1 1 FAM194 protein Glyco_transf_15 PF01793.11 KND98007.1 - 3.7e-115 384.4 5.6 4.5e-115 384.1 3.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase RFXA_RFXANK_bdg PF15289.1 KND98007.1 - 0.21 11.7 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain Mannosyl_trans3 PF11051.3 KND98008.1 - 1.4e-83 280.4 0.0 2.2e-83 279.7 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Clat_adaptor_s PF01217.15 KND98010.1 - 1.6e-51 173.8 1.7 1.8e-51 173.5 1.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DEAD PF00270.24 KND98011.1 - 4.8e-47 159.5 0.0 1.3e-46 158.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND98011.1 - 4e-22 77.8 0.0 1e-21 76.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 KND98011.1 - 3e-21 74.9 7.7 3e-21 74.9 5.3 2.8 2 1 1 3 3 3 1 DBP10CT (NUC160) domain DUF482 PF04339.7 KND98011.1 - 0.16 10.8 4.4 0.083 11.7 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF482 RRM_1 PF00076.17 KND98012.1 - 2.2e-36 123.3 0.1 7.8e-18 63.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND98012.1 - 2.8e-32 110.5 0.0 1.4e-15 57.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND98012.1 - 4.8e-13 48.7 0.0 3.1e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MCRS_N PF13325.1 KND98012.1 - 0.058 12.8 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein RRM_3 PF08777.6 KND98012.1 - 0.071 12.9 0.0 4.5 7.1 0.0 2.6 2 0 0 2 2 2 0 RNA binding motif Med15 PF09606.5 KND98012.1 - 1.8 6.6 62.4 0.11 10.6 20.2 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal UPF0020 PF01170.13 KND98014.1 - 8.2e-14 51.5 0.0 1.9e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 KND98014.1 - 2.7e-08 33.8 0.0 5.3e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 KND98014.1 - 0.0079 15.3 0.1 0.061 12.3 0.0 2.3 3 0 0 3 3 3 1 N-6 DNA Methylase N6_N4_Mtase PF01555.13 KND98014.1 - 0.011 15.2 0.1 0.71 9.3 0.0 2.5 2 1 0 2 2 2 0 DNA methylase Thi4 PF01946.12 KND98015.1 - 3.3e-104 347.0 0.0 3.9e-104 346.7 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KND98015.1 - 8.9e-09 34.6 0.4 2.2e-07 30.1 0.3 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND98015.1 - 5.7e-07 29.4 0.1 2.5e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KND98015.1 - 8.6e-07 28.1 2.4 7.2e-05 21.8 0.8 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KND98015.1 - 1.5e-06 27.3 0.3 5e-06 25.6 0.2 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KND98015.1 - 5.4e-06 26.4 0.0 8.5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KND98015.1 - 4.8e-05 23.1 0.9 0.00099 18.9 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KND98015.1 - 7.8e-05 22.8 0.2 0.00013 22.0 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KND98015.1 - 0.0019 16.7 0.4 0.0032 16.0 0.3 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 KND98015.1 - 0.0029 16.7 0.0 0.0039 16.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KND98015.1 - 0.0032 16.3 0.5 0.0058 15.5 0.2 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KND98015.1 - 0.0068 15.4 0.2 0.012 14.6 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.15 KND98015.1 - 0.044 13.8 0.0 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.9 KND98015.1 - 0.074 11.6 0.2 0.11 11.1 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase CPSF73-100_C PF11718.3 KND98016.1 - 1.1e-64 217.7 10.3 1.9e-64 216.9 7.1 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 KND98016.1 - 7.2e-36 122.9 0.0 4e-35 120.4 0.0 2.4 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 KND98016.1 - 3.7e-15 56.0 0.3 9.1e-15 54.8 0.2 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KND98016.1 - 1.9e-12 47.1 0.1 4.8e-12 45.8 0.1 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KND98016.1 - 3.5e-07 30.0 0.5 1.9e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 KND98016.1 - 1.1e-06 28.3 0.1 2.5e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase LSM PF01423.17 KND98017.1 - 4.1e-15 55.0 0.3 6e-15 54.5 0.2 1.2 1 0 0 1 1 1 1 LSM domain Mu-like_Com PF10122.4 KND98017.1 - 0.14 11.2 0.5 0.34 10.0 0.3 1.7 1 1 0 1 1 1 0 Mu-like prophage protein Com Hus1 PF04005.7 KND98018.1 - 7.5e-64 215.4 1.5 8.4e-64 215.3 1.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Aminotran_5 PF00266.14 KND98019.1 - 5.2e-34 117.5 0.0 6.1e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V GTP_EFTU PF00009.22 KND98020.1 - 9.7e-48 162.0 0.0 1.5e-47 161.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 KND98020.1 - 4.9e-35 119.6 6.9 4.9e-35 119.6 4.8 2.0 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 KND98020.1 - 1.8e-20 72.5 0.0 3.9e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KND98020.1 - 1.1e-05 25.4 0.0 2.4e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.17 KND98020.1 - 0.00018 20.9 0.0 0.00033 20.0 0.0 1.4 1 0 0 1 1 1 1 Ras family EFG_II PF14492.1 KND98020.1 - 0.002 17.9 0.0 0.0093 15.7 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II SRPRB PF09439.5 KND98020.1 - 0.012 14.8 0.0 0.036 13.2 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF3323 PF11796.3 KND98020.1 - 0.17 11.1 1.8 0.29 10.4 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) PALP PF00291.20 KND98021.1 - 2.4e-73 247.0 0.0 3.1e-73 246.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 KND98021.1 - 8.8e-45 150.2 0.2 1.3e-26 92.0 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase EF-hand_1 PF00036.27 KND98022.1 - 2.4e-11 42.0 0.7 0.00045 19.3 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 KND98022.1 - 8.4e-10 38.6 1.3 6.9e-05 22.9 0.1 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KND98022.1 - 1e-09 37.2 0.4 0.00022 20.4 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KND98022.1 - 9.4e-09 34.4 2.9 0.04 13.7 0.1 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 KND98022.1 - 0.0012 18.4 2.9 0.14 11.7 0.0 3.7 3 2 1 4 4 4 1 EF-hand domain pair PAT1 PF09770.4 KND98022.1 - 1.2 7.3 41.7 1.4 7.0 28.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EII-Sor PF03609.9 KND98024.1 - 0.38 9.9 0.8 0.57 9.4 0.5 1.2 1 0 0 1 1 1 0 PTS system sorbose-specific iic component Per1 PF04080.8 KND98025.1 - 2e-81 273.3 12.1 2.7e-81 272.9 8.4 1.1 1 0 0 1 1 1 1 Per1-like CK_II_beta PF01214.13 KND98027.1 - 0.075 12.5 0.5 0.1 12.1 0.3 1.2 1 0 0 1 1 1 0 Casein kinase II regulatory subunit Neural_ProG_Cyt PF06567.6 KND98028.1 - 0.62 10.1 5.3 0.38 10.8 0.2 2.7 2 1 1 3 3 3 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain DUF2404 PF10296.4 KND98029.1 - 5.1e-25 87.4 1.3 6.5e-25 87.0 0.1 1.8 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) PH_11 PF15413.1 KND98029.1 - 4.2e-15 55.9 0.1 1.6e-14 54.0 0.1 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KND98029.1 - 3.4e-06 27.1 0.3 2.6e-05 24.3 0.0 2.6 2 1 0 3 3 3 1 PH domain Marek_SORF3 PF07153.6 KND98029.1 - 0.025 13.2 0.0 0.043 12.5 0.0 1.3 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein PI3_PI4_kinase PF00454.22 KND98030.1 - 5.9e-47 160.1 1.0 1.8e-46 158.5 0.2 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.8 KND98030.1 - 3.4e-25 88.0 0.9 3.4e-25 88.0 0.6 4.1 3 0 0 3 3 3 1 UME (NUC010) domain FAT PF02259.18 KND98030.1 - 9.3e-25 87.3 6.5 5.2e-24 84.8 3.3 2.7 2 1 0 2 2 2 1 FAT domain FATC PF02260.15 KND98030.1 - 6.3e-15 54.3 0.0 1.4e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 FATC domain CKS PF01111.14 KND98031.1 - 2.2e-34 117.0 0.1 2.7e-34 116.8 0.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit PRMT5 PF05185.11 KND98032.1 - 4.2e-72 243.4 0.2 5.2e-72 243.1 0.2 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_26 PF13659.1 KND98032.1 - 1.3e-07 31.6 0.0 2.6e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND98032.1 - 2.6e-06 27.9 0.0 6.9e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND98032.1 - 0.00014 21.4 0.0 0.00065 19.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND98032.1 - 0.00024 21.4 0.0 0.00093 19.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KND98032.1 - 0.0032 16.8 0.0 0.0066 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DUF3374 PF11854.3 KND98032.1 - 0.042 12.1 0.0 0.064 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3374) Methyltransf_12 PF08242.7 KND98032.1 - 0.12 12.8 0.0 0.48 10.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 KND98032.1 - 0.14 12.6 0.0 0.35 11.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cir_N PF10197.4 KND98033.1 - 7.2e-14 51.5 11.1 7.2e-14 51.5 7.7 2.7 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR CWC25 PF12542.3 KND98033.1 - 9.1e-12 45.2 0.3 9.1e-12 45.2 0.2 3.0 1 1 2 3 3 3 1 Pre-mRNA splicing factor Cgr1 PF03879.9 KND98033.1 - 0.018 15.2 6.7 0.018 15.2 4.7 3.1 3 1 0 3 3 3 0 Cgr1 family CTP_transf_1 PF01148.15 KND98036.1 - 2e-78 263.6 18.7 2.8e-78 263.1 13.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family DUF1212 PF06738.7 KND98036.1 - 0.15 11.4 11.0 2.2 7.6 2.6 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1212) DUF962 PF06127.6 KND98036.1 - 3.2 7.7 7.8 4.1 7.3 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF962) TFIIA PF03153.8 KND98037.1 - 0.21 11.4 9.6 0.32 10.8 6.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 KND98037.1 - 3.1 5.9 9.2 4.4 5.4 6.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Pol_alpha_B_N PF08418.5 KND98037.1 - 4.3 6.8 16.8 7.7 5.9 11.6 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal RAP1 PF07218.6 KND98037.1 - 7.3 4.5 13.7 11 3.9 9.5 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF706 PF05153.10 KND98038.1 - 6e-124 412.3 6.2 8.7e-124 411.8 4.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 KND98038.1 - 0.048 13.6 0.6 0.57 10.2 0.0 2.6 2 2 0 2 2 2 0 HD domain Complex1_51K PF01512.12 KND98039.1 - 6.5e-46 155.7 0.0 1.5e-45 154.6 0.0 1.6 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 KND98039.1 - 2.4e-19 68.1 0.4 5.3e-19 67.1 0.3 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 KND98039.1 - 2e-06 27.6 0.0 4.8e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 SLBB domain Glyco_transf_15 PF01793.11 KND98040.1 - 8.3e-129 429.2 11.9 1.1e-128 428.9 8.2 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ebp2 PF05890.7 KND98041.1 - 5.7e-86 288.1 20.3 5.7e-86 288.1 14.1 2.6 2 1 1 3 3 3 1 Eukaryotic rRNA processing protein EBP2 polyprenyl_synt PF00348.12 KND98042.1 - 1.2e-80 270.1 0.0 1.4e-80 269.8 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase UcrQ PF02939.11 KND98043.1 - 1.6e-29 101.5 0.8 1.8e-29 101.3 0.6 1.0 1 0 0 1 1 1 1 UcrQ family Ribosomal_L22 PF00237.14 KND98045.1 - 2e-32 111.2 0.2 3.2e-32 110.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e SWIRM PF04433.12 KND98046.1 - 2e-32 111.1 0.9 6.4e-32 109.5 0.1 2.2 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 KND98046.1 - 1.1e-05 25.4 0.1 2.3e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KND98046.1 - 0.00017 21.5 0.0 0.00041 20.3 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain GTP_EFTU PF00009.22 KND98048.1 - 1.4e-29 102.8 0.0 2e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KND98048.1 - 8.2e-18 64.1 0.0 1.4e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KND98048.1 - 1.4e-14 53.7 0.0 5.7e-14 51.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus Miro PF08477.8 KND98048.1 - 1.7e-09 38.2 0.0 3.8e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KND98048.1 - 8.2e-07 28.9 0.0 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 KND98048.1 - 0.0061 16.3 0.0 0.017 14.9 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II FeoB_N PF02421.13 KND98048.1 - 0.022 14.0 0.3 7.5 5.8 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.18 KND98048.1 - 0.06 13.1 0.2 4.3 7.1 0.0 2.4 1 1 0 2 2 2 0 Dynamin family RNA_pol_Rpb4 PF03874.11 KND98049.1 - 3.3e-31 107.7 7.2 4.8e-31 107.1 5.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 Pkinase PF00069.20 KND98050.1 - 9.2e-54 182.3 0.0 3.8e-53 180.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND98050.1 - 1.6e-22 79.8 0.0 2.9e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KND98050.1 - 6.3e-06 26.0 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND98050.1 - 0.0029 17.2 0.6 0.005 16.4 0.4 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KND98050.1 - 0.0089 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KND98050.1 - 0.028 13.7 0.0 0.06 12.6 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Tim17 PF02466.14 KND98051.1 - 3.3e-34 117.6 8.6 3.9e-34 117.4 6.0 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family AA_permease_2 PF13520.1 KND98053.1 - 3.3e-47 160.9 52.0 4.3e-47 160.6 36.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KND98053.1 - 5.3e-33 114.0 45.0 7e-33 113.6 31.2 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3353 PF11833.3 KND98053.1 - 4.1 6.8 6.9 3.7 6.9 3.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3353) Ribosomal_L1 PF00687.16 KND98054.1 - 7.2e-44 149.7 0.9 8.9e-44 149.4 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Palm_thioest PF02089.10 KND98055.1 - 4.7e-45 153.7 0.1 5.6e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.9 KND98055.1 - 0.0056 15.9 0.1 0.0089 15.3 0.1 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 KND98055.1 - 0.047 13.2 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF98 PF01947.11 KND98055.1 - 0.072 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF98) cwf18 PF08315.7 KND98057.1 - 0.02 15.3 6.2 0.047 14.1 4.3 1.6 1 1 0 1 1 1 0 cwf18 pre-mRNA splicing factor CAF1C_H4-bd PF12265.3 KND98060.1 - 3.7e-18 65.1 0.2 8.1e-18 64.0 0.1 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 KND98060.1 - 1.7e-14 53.0 16.5 0.00019 21.1 0.3 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KND98060.1 - 5.8e-05 22.8 1.5 0.4 10.3 0.1 3.6 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Vps51 PF08700.6 KND98061.1 - 1e-07 31.6 1.2 2e-07 30.7 0.8 1.6 1 1 0 1 1 1 1 Vps51/Vps67 Methyltransf_31 PF13847.1 KND98062.1 - 1.1e-22 80.2 0.2 1.6e-22 79.7 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND98062.1 - 2e-15 57.3 0.0 3.4e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND98062.1 - 1.8e-07 31.5 0.0 3.8e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND98062.1 - 2.8e-07 30.8 0.0 4.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND98062.1 - 7.7e-05 23.1 0.0 0.00016 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND98062.1 - 0.00013 21.7 0.1 0.00045 19.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND98062.1 - 0.00033 20.6 0.0 0.00054 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KND98062.1 - 0.00052 19.7 0.0 0.0006 19.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND98062.1 - 0.015 14.4 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Ran_BP1 PF00638.13 KND98063.1 - 8.3e-26 90.4 0.1 1.5e-25 89.6 0.1 1.4 1 0 0 1 1 1 1 RanBP1 domain zf-RING_2 PF13639.1 KND98064.1 - 6.6e-09 35.4 10.0 6.6e-09 35.4 6.9 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KND98064.1 - 1.4e-08 34.5 10.7 1.4e-08 34.5 7.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KND98064.1 - 1e-07 31.4 10.6 1e-07 31.4 7.3 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KND98064.1 - 1.1e-07 31.3 6.2 1.1e-07 31.3 4.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND98064.1 - 3.9e-07 29.6 9.0 3.9e-07 29.6 6.2 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KND98064.1 - 1.5e-06 27.9 7.3 1.5e-06 27.9 5.1 2.6 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KND98064.1 - 2.4e-05 23.9 2.3 2.4e-05 23.9 1.6 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 KND98064.1 - 0.00096 19.2 12.2 0.00097 19.1 5.9 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 KND98064.1 - 0.0045 16.7 2.7 0.0045 16.7 1.8 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 KND98064.1 - 0.0081 15.6 4.8 0.0081 15.6 3.4 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 DUF3716 PF12511.3 KND98064.1 - 0.03 13.9 1.3 0.03 13.9 0.9 2.3 2 0 0 2 2 1 0 Protein of unknown function (DUF3716) Rtf2 PF04641.7 KND98064.1 - 0.081 12.1 0.2 0.15 11.2 0.1 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger CpXC PF14353.1 KND98064.1 - 0.09 12.7 4.1 2.6 7.9 0.0 3.4 3 1 0 3 3 3 0 CpXC protein DZR PF12773.2 KND98064.1 - 0.17 11.7 11.3 3.6 7.4 3.6 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.1 KND98064.1 - 0.72 9.4 13.7 0.03 13.8 4.7 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 KND98064.1 - 1.8 8.4 8.2 0.14 11.9 1.7 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger IBR PF01485.16 KND98064.1 - 2.2 8.2 13.4 7.7 6.4 6.1 2.8 2 1 0 2 2 2 0 IBR domain PolC_DP2 PF03833.8 KND98064.1 - 2.7 5.5 9.6 0.35 8.4 0.5 2.4 1 1 1 3 3 3 0 DNA polymerase II large subunit DP2 zinc-ribbons_6 PF07191.7 KND98064.1 - 3.3 7.5 10.4 0.72 9.6 2.9 2.3 2 0 0 2 2 2 0 zinc-ribbons HUN PF08729.5 KND98064.1 - 8.9 6.2 12.1 0.3 10.9 0.6 3.4 3 0 0 3 3 3 0 HPC2 and ubinuclein domain DUF3954 PF13128.1 KND98065.1 - 0.032 13.6 0.2 0.057 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3954) Matrix PF00661.16 KND98065.1 - 0.079 11.2 0.0 0.098 10.9 0.0 1.1 1 0 0 1 1 1 0 Viral matrix protein NTF2 PF02136.15 KND98066.1 - 7.1e-13 48.9 0.1 1.3e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Ribosomal_S21 PF01165.15 KND98068.1 - 9.5e-06 24.9 0.0 1.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 DUF1681 PF07933.9 KND98070.1 - 2.3e-05 24.0 0.0 8.7e-05 22.1 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1681) Helicase_C_3 PF13625.1 KND98071.1 - 2.3e-26 92.0 0.0 7.2e-26 90.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND98071.1 - 7.1e-14 52.0 0.0 1.7e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KND98071.1 - 5.8e-13 48.3 0.1 9.4e-13 47.6 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KND98071.1 - 4e-11 42.6 0.0 9.1e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KND98071.1 - 2.8e-07 30.1 0.0 5.8e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SRP40_C PF05022.7 KND98072.1 - 4.4e-31 107.2 4.7 9.6e-31 106.1 3.3 1.6 1 0 0 1 1 1 1 SRP40, C-terminal domain Macoilin PF09726.4 KND98072.1 - 0.023 13.0 19.4 0.022 13.0 13.4 1.1 1 0 0 1 1 1 0 Transmembrane protein CDC45 PF02724.9 KND98072.1 - 0.032 12.2 14.9 0.03 12.3 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein RAP1 PF07218.6 KND98072.1 - 1.3 7.0 19.3 1.3 7.0 13.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SOBP PF15279.1 KND98072.1 - 1.5 9.1 12.3 1.8 8.8 8.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF605 PF04652.11 KND98072.1 - 3 7.1 19.7 3.3 7.0 13.7 1.1 1 0 0 1 1 1 0 Vta1 like SDA1 PF05285.7 KND98072.1 - 3.5 6.7 21.7 3.9 6.6 15.0 1.2 1 0 0 1 1 1 0 SDA1 DUF572 PF04502.8 KND98072.1 - 4.6 6.3 18.2 4.9 6.2 12.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Abhydrolase_6 PF12697.2 KND98074.1 - 1.1e-27 97.4 0.0 1.3e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND98074.1 - 1.1e-09 38.1 0.0 2.1e-09 37.3 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KND98074.1 - 1.9e-08 34.1 0.0 3.6e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KND98074.1 - 8.4e-06 25.3 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 KND98074.1 - 0.00014 21.1 0.0 0.00025 20.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family PGAP1 PF07819.8 KND98074.1 - 0.00071 19.2 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_2 PF02230.11 KND98074.1 - 0.002 17.6 0.6 0.017 14.5 0.4 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase LCAT PF02450.10 KND98074.1 - 0.0061 15.5 0.0 0.0098 14.9 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF3589 PF12141.3 KND98075.1 - 5.7e-137 456.9 0.0 6.8e-137 456.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3589) Pkinase PF00069.20 KND98076.1 - 2.1e-65 220.4 0.0 3.4e-65 219.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND98076.1 - 5.5e-48 163.2 0.0 9.2e-48 162.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND98076.1 - 2e-06 26.9 0.1 6.4e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KND98076.1 - 0.0025 17.5 0.0 0.0049 16.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KND98076.1 - 0.063 12.6 0.0 0.25 10.6 0.0 1.8 1 1 0 1 1 1 0 RIO1 family Kdo PF06293.9 KND98076.1 - 0.11 11.5 0.0 0.29 10.1 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3987 PF13148.1 KND98077.1 - 0.26 9.8 13.5 1.4 7.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Mit_ribos_Mrp51 PF11709.3 KND98078.1 - 1.3e-81 274.2 1.0 1.7e-81 273.8 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit DUF3722 PF12519.3 KND98079.1 - 3.7e-83 278.7 3.7 3.7e-83 278.7 2.5 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3722) CDC14 PF08045.6 KND98080.1 - 7.8e-53 179.2 0.9 1e-52 178.8 0.6 1.1 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Med8 PF10232.4 KND98080.1 - 0.032 13.7 0.4 0.049 13.1 0.3 1.3 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 DUF3464 PF11947.3 KND98081.1 - 0.083 12.3 0.1 0.2 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) GWT1 PF06423.7 KND98081.1 - 0.29 11.2 8.1 0.076 13.1 1.2 2.8 3 0 0 3 3 3 0 GWT1 Grp1_Fun34_YaaH PF01184.14 KND98082.1 - 3.1e-76 255.3 20.6 3.6e-76 255.1 14.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF973 PF06157.6 KND98082.1 - 0.07 12.0 6.9 0.071 12.0 4.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF973) Las1 PF04031.8 KND98084.1 - 2.5e-37 127.8 0.0 4.1e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 Las1-like ATG2_CAD PF13329.1 KND98085.1 - 1.7e-42 144.6 0.0 8.5e-42 142.3 0.0 2.3 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 KND98085.1 - 5.3e-28 97.0 0.1 1.7e-27 95.4 0.1 2.0 1 0 0 1 1 1 1 ATG C terminal domain Fungal_trans_2 PF11951.3 KND98085.1 - 0.0012 17.5 1.6 0.0019 16.8 0.3 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Nucleos_tra2_C PF07662.8 KND98087.1 - 2.8e-63 213.2 1.3 2.8e-63 213.2 0.9 2.0 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 KND98087.1 - 4.8e-21 74.8 3.1 4.8e-21 74.8 2.2 3.8 5 0 0 5 5 5 1 Na+ dependent nucleoside transporter N-terminus Vps35 PF03635.12 KND98088.1 - 9.1e-236 784.6 23.1 1.1e-235 784.4 16.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 PNGaseA PF12222.3 KND98089.1 - 4.8e-57 193.7 1.2 1.4e-33 116.4 0.1 2.1 1 1 1 2 2 2 2 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A tRNA_int_endo PF01974.12 KND98090.1 - 4.1e-17 61.7 0.0 8.2e-17 60.7 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain FtsH_ext PF06480.10 KND98091.1 - 0.091 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 FtsH Extracellular zf-CSL PF05207.8 KND98096.1 - 1.8e-23 81.8 0.4 2.5e-23 81.3 0.3 1.2 1 0 0 1 1 1 1 CSL zinc finger TF_Zn_Ribbon PF08271.7 KND98096.1 - 0.079 12.2 3.0 0.14 11.5 0.6 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding Prok-RING_1 PF14446.1 KND98096.1 - 0.24 11.1 1.8 0.55 10.0 1.2 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Ribosomal_S8e PF01201.17 KND98097.1 - 1.9e-51 173.6 2.5 2.3e-51 173.3 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e NAD_binding_9 PF13454.1 KND98097.1 - 0.035 13.8 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding Tombus_movement PF05318.7 KND98097.1 - 9.5 6.9 6.6 10 6.8 0.3 2.2 2 0 0 2 2 2 0 Tombusvirus movement protein Peptidase_C1_2 PF03051.10 KND98098.1 - 9.3e-157 522.0 4.3 1.1e-156 521.8 3.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 KND98098.1 - 1.8e-06 28.0 2.1 0.0062 16.4 0.5 3.4 3 1 1 4 4 4 2 Papain family cysteine protease AA_permease PF00324.16 KND98099.1 - 3.7e-116 388.2 43.4 4.5e-116 388.0 30.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND98099.1 - 3.9e-30 104.7 46.7 5.5e-30 104.2 32.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4179 PF13786.1 KND98100.1 - 0.016 15.4 0.2 0.017 15.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) BP28CT PF08146.7 KND98103.1 - 6.9e-46 155.7 2.7 6.9e-46 155.7 1.9 4.0 4 0 0 4 4 4 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 KND98103.1 - 6.3e-12 45.5 0.1 6.3e-12 45.5 0.0 4.7 5 0 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 Cpn10 PF00166.16 KND98104.1 - 2.5e-29 101.0 0.0 2.8e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit MARVEL PF01284.18 KND98105.1 - 0.0013 18.5 12.5 0.0021 17.8 8.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF2759 PF10958.3 KND98105.1 - 0.012 15.1 1.9 0.033 13.7 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2759) Ras PF00071.17 KND98106.1 - 3.3e-52 176.1 0.2 5.9e-52 175.3 0.1 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KND98106.1 - 2.8e-19 69.7 0.0 4.3e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KND98106.1 - 7.2e-16 57.9 0.0 8.9e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KND98106.1 - 2.2e-07 30.2 0.0 2.8e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KND98106.1 - 6.4e-06 25.7 0.0 1.2e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KND98106.1 - 3.6e-05 23.7 0.0 5.3e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KND98106.1 - 0.0023 18.0 0.0 2.7 8.1 0.0 2.3 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KND98106.1 - 0.0098 15.8 0.2 0.075 13.0 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.15 KND98106.1 - 0.019 13.6 0.0 2.1 6.9 0.0 2.7 2 1 1 3 3 3 0 G-protein alpha subunit DUF258 PF03193.11 KND98106.1 - 0.048 12.8 0.0 0.12 11.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 MBF1 PF08523.5 KND98107.1 - 2.2e-26 91.6 2.7 2.2e-26 91.6 1.9 2.1 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 KND98107.1 - 2.2e-15 56.2 0.4 7.2e-15 54.5 0.2 1.8 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.1 KND98107.1 - 7.8e-08 32.4 0.0 1.7e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 KND98107.1 - 4.7e-06 26.5 0.1 8.1e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.1 KND98107.1 - 0.14 11.7 0.1 0.26 10.9 0.1 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain Steroid_dh PF02544.11 KND98109.1 - 4.5e-33 114.1 7.8 4.5e-33 114.1 5.4 1.8 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF621 PF04789.10 KND98109.1 - 0.0025 16.8 1.9 0.0038 16.2 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF621) SelR PF01641.13 KND98110.1 - 3.7e-51 172.0 0.0 4.1e-51 171.8 0.0 1.0 1 0 0 1 1 1 1 SelR domain zf-Mss51 PF13824.1 KND98110.1 - 0.043 13.6 1.9 0.13 12.1 0.1 2.5 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DZR PF12773.2 KND98110.1 - 0.84 9.4 3.4 5.3 6.9 0.2 2.3 1 1 1 2 2 2 0 Double zinc ribbon Methyltransf_31 PF13847.1 KND98111.1 - 4.9e-14 52.1 0.1 9.5e-14 51.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KND98111.1 - 6.9e-12 45.0 0.0 9.5e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PRMT5 PF05185.11 KND98111.1 - 2.2e-10 40.0 0.0 2.8e-10 39.7 0.0 1.0 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.2 KND98111.1 - 8.3e-10 39.2 0.1 3.5e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND98111.1 - 1.1e-09 38.2 0.0 2.5e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND98111.1 - 2.5e-09 37.5 0.0 6.4e-09 36.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KND98111.1 - 5.4e-07 28.6 0.1 7.8e-07 28.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 KND98111.1 - 7.1e-07 28.7 0.1 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KND98111.1 - 2.9e-06 27.5 0.0 9.3e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND98111.1 - 7.7e-06 25.7 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KND98111.1 - 1.7e-05 24.0 0.0 2.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 KND98111.1 - 6.3e-05 23.3 0.0 0.00013 22.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KND98111.1 - 0.00045 19.7 0.0 0.00069 19.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 KND98111.1 - 0.002 18.1 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase UPF0020 PF01170.13 KND98111.1 - 0.0076 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 TehB PF03848.9 KND98111.1 - 0.0088 15.2 0.1 0.022 13.9 0.0 1.7 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.13 KND98111.1 - 0.01 14.9 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 KND98111.1 - 0.014 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 KND98111.1 - 0.063 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 KND98111.1 - 0.11 13.3 0.0 0.21 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 KND98112.1 - 9.7e-35 119.9 19.1 9.7e-35 119.9 13.3 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily ERK-JNK_inhib PF15002.1 KND98112.1 - 0.016 14.5 0.1 0.023 14.0 0.1 1.2 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor DUF2085 PF09858.4 KND98112.1 - 0.18 11.9 3.5 11 6.1 0.2 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2085) MFS_2 PF13347.1 KND98112.1 - 0.84 7.9 21.3 1.3 7.3 10.7 3.1 2 1 0 2 2 2 0 MFS/sugar transport protein DUF2305 PF10230.4 KND98113.1 - 5.9e-62 209.4 0.2 6.8e-62 209.2 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 KND98113.1 - 2.1e-08 34.3 0.0 2.5e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND98113.1 - 0.00021 21.0 0.0 0.00025 20.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KND98113.1 - 0.025 13.8 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) NRDE PF05742.7 KND98114.1 - 8.8e-48 162.9 0.0 1.4e-47 162.3 0.0 1.3 1 1 0 1 1 1 1 NRDE protein Pkinase PF00069.20 KND98115.1 - 6.2e-50 169.7 0.0 1.9e-49 168.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND98115.1 - 1.9e-25 89.4 0.2 1.2e-24 86.8 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 KND98115.1 - 0.036 13.1 0.1 0.1 11.6 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C2HC5 PF06221.8 KND98117.1 - 1.6e-23 82.1 6.2 2.7e-23 81.4 4.3 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type HrpA_pilin PF09589.5 KND98117.1 - 1 9.7 13.4 0.57 10.6 0.5 3.5 3 1 1 4 4 4 0 HrpA pilus formation protein Drc1-Sld2 PF11719.3 KND98118.1 - 1.1e-64 219.1 24.0 1.5e-64 218.7 16.6 1.1 1 0 0 1 1 1 1 DNA replication and checkpoint protein Oligomerisation PF02410.10 KND98119.1 - 9.2e-19 67.3 0.0 2e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Oligomerisation domain mRNA_stabil PF13929.1 KND98119.1 - 0.024 13.5 0.2 0.22 10.4 0.0 2.2 2 0 0 2 2 2 0 mRNA stabilisation Utp11 PF03998.8 KND98121.1 - 1.5e-71 241.0 35.5 1.7e-71 240.9 24.6 1.0 1 0 0 1 1 1 1 Utp11 protein KTI12 PF08433.5 KND98122.1 - 4.5e-97 324.4 0.0 5.1e-97 324.3 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 KND98122.1 - 1.9e-05 25.0 0.0 3.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KND98122.1 - 6e-05 23.8 0.0 0.00012 22.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KND98122.1 - 0.0001 22.2 0.0 0.00039 20.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.15 KND98122.1 - 0.11 12.0 0.0 0.37 10.4 0.0 1.9 1 1 0 1 1 1 0 Adenylylsulphate kinase MMR_HSR1 PF01926.18 KND98123.1 - 3.1e-13 49.6 0.2 1.2e-12 47.7 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KND98123.1 - 0.00018 20.7 0.1 0.00038 19.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 KND98123.1 - 0.00018 20.7 0.4 0.0061 15.8 0.3 2.4 1 1 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.11 KND98123.1 - 0.0038 16.3 0.0 0.009 15.1 0.0 1.7 1 0 0 1 1 1 1 AIG1 family Nop16 PF09420.5 KND98123.1 - 0.03 14.4 0.0 0.13 12.4 0.0 1.9 1 1 0 1 1 1 0 Ribosome biogenesis protein Nop16 Dynamin_N PF00350.18 KND98123.1 - 0.043 13.6 0.2 24 4.7 0.0 3.2 2 1 1 3 3 3 0 Dynamin family Miro PF08477.8 KND98123.1 - 0.053 14.0 0.0 0.17 12.3 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 KND98123.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 KND98123.1 - 0.62 10.8 4.0 2.3 9.0 0.0 3.0 3 1 0 3 3 3 0 AAA domain Ku PF02735.11 KND98124.1 - 8.7e-19 67.7 1.0 1.4e-18 67.0 0.2 1.7 1 1 1 2 2 2 1 Ku70/Ku80 beta-barrel domain TMEM156 PF15106.1 KND98124.1 - 0.12 11.6 4.0 3 7.0 0.8 2.9 3 0 0 3 3 3 0 TMEM156 protein family Alpha-amylase_C PF02806.13 KND98126.1 - 5.9e-24 84.0 0.4 2.3e-23 82.1 0.0 2.2 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 KND98126.1 - 1.4e-19 70.6 0.4 7.7e-18 64.9 0.2 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 KND98126.1 - 1.2e-14 54.1 0.1 2.7e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) GHL6 PF14871.1 KND98126.1 - 0.014 15.3 0.0 0.065 13.2 0.0 2.1 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Glyco_hydro_66 PF13199.1 KND98126.1 - 0.018 13.5 0.5 0.027 12.8 0.3 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 WD40 PF00400.27 KND98127.1 - 4.7e-40 134.0 20.6 8e-08 31.8 0.3 10.0 10 0 0 10 10 10 8 WD domain, G-beta repeat CPSF_A PF03178.10 KND98127.1 - 0.014 14.4 0.0 1.6 7.7 0.0 2.4 2 0 0 2 2 2 0 CPSF A subunit region PQQ_3 PF13570.1 KND98127.1 - 0.019 15.2 0.1 6.2 7.2 0.0 4.1 3 0 0 3 3 3 0 PQQ-like domain PD40 PF07676.7 KND98127.1 - 0.035 13.7 4.4 13 5.5 0.0 5.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF1668 PF07893.8 KND98127.1 - 0.058 12.5 0.0 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1668) Actin PF00022.14 KND98128.1 - 1.9e-108 362.4 0.0 2.4e-108 362.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KND98128.1 - 0.011 14.3 0.0 1 7.8 0.0 2.6 3 0 0 3 3 3 0 MreB/Mbl protein Mitofilin PF09731.4 KND98129.1 - 1.5e-111 373.8 30.4 8.2e-100 335.1 19.7 2.1 1 1 1 2 2 2 2 Mitochondrial inner membrane protein DASH_Dad1 PF08649.5 KND98129.1 - 0.00016 21.3 1.4 0.008 15.8 0.1 2.7 2 0 0 2 2 2 1 DASH complex subunit Dad1 HHH_5 PF14520.1 KND98129.1 - 0.014 15.5 0.2 0.1 12.7 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain Phasin PF05597.6 KND98129.1 - 0.081 12.6 17.5 0.27 10.9 0.0 3.6 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) UCH PF00443.24 KND98129.1 - 0.47 9.5 3.7 0.72 8.9 2.5 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Acid_PPase PF12689.2 KND98129.1 - 3.5 7.2 6.5 14 5.2 1.5 2.3 1 1 1 2 2 2 0 Acid Phosphatase Sulfatase PF00884.18 KND98130.1 - 1.4e-72 244.4 0.0 7.7e-72 242.0 0.0 1.8 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KND98130.1 - 8.7e-06 25.2 0.0 0.0053 16.1 0.0 2.5 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 KND98130.1 - 0.0004 20.6 1.0 0.012 15.9 0.2 2.6 2 1 0 2 2 2 1 C-terminal region of aryl-sulfatase DUF229 PF02995.12 KND98130.1 - 0.0017 16.8 0.0 0.0023 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Cupin_5 PF06172.6 KND98131.1 - 2.7e-45 153.7 0.0 3.1e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) HRXXH PF13933.1 KND98132.1 - 3.8e-93 311.4 0.6 5.7e-93 310.8 0.4 1.1 1 0 0 1 1 1 1 Putative peptidase family Pkinase PF00069.20 KND98133.1 - 2.1e-58 197.5 0.0 6e-58 196.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND98133.1 - 1.6e-34 119.2 2.5 1.5e-22 79.9 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KND98133.1 - 0.0011 17.8 0.8 0.081 11.7 0.0 2.6 3 0 0 3 3 3 2 Poxvirus serine/threonine protein kinase APH PF01636.18 KND98133.1 - 0.029 14.1 0.2 0.26 11.0 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family IMD PF08397.6 KND98133.1 - 0.47 9.7 23.7 0.12 11.7 7.8 2.6 1 1 1 2 2 2 0 IRSp53/MIM homology domain SAICAR_synt PF01259.13 KND98134.1 - 6.5e-100 333.3 0.7 9e-100 332.8 0.5 1.2 1 0 0 1 1 1 1 SAICAR synthetase APS_kinase PF01583.15 KND98136.1 - 7.8e-73 243.3 0.0 9.7e-73 242.9 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 KND98136.1 - 2.9e-08 33.7 0.0 5.2e-08 32.8 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KND98136.1 - 2e-05 25.4 0.1 3.4e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 KND98136.1 - 6e-05 22.3 0.0 7.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 KND98136.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KND98136.1 - 0.0018 18.5 0.1 0.0033 17.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KND98136.1 - 0.006 15.6 0.0 0.0089 15.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin CPT PF07931.7 KND98136.1 - 0.012 15.2 0.1 0.43 10.1 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.1 KND98136.1 - 0.029 14.6 0.2 0.044 14.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain CbiA PF01656.18 KND98136.1 - 0.076 12.4 0.0 0.076 12.4 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.22 KND98136.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 1 0 1 1 1 0 ABC transporter Snf7 PF03357.16 KND98137.1 - 6.8e-29 100.4 25.3 2.7e-28 98.5 15.9 2.0 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.9 KND98137.1 - 6.6e-06 25.6 4.9 1.2e-05 24.7 3.4 1.6 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Uds1 PF15456.1 KND98137.1 - 0.094 12.7 0.3 0.094 12.7 0.2 2.5 2 0 0 2 2 2 0 Up-regulated During Septation HTH_38 PF13936.1 KND98137.1 - 0.38 10.3 2.7 0.34 10.4 0.4 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain APG6 PF04111.7 KND98137.1 - 3.1 6.7 12.5 0.12 11.3 4.1 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 EAP30 PF04157.11 KND98137.1 - 3.5 6.7 12.7 0.055 12.6 0.5 2.2 2 0 0 2 2 2 0 EAP30/Vps36 family Cu-oxidase_3 PF07732.10 KND98138.1 - 4e-46 155.5 1.3 6e-43 145.3 0.2 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KND98138.1 - 1e-44 151.3 10.5 2.9e-41 140.2 0.4 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KND98138.1 - 8.3e-36 123.2 2.8 1e-31 109.9 0.1 2.9 3 0 0 3 3 3 2 Multicopper oxidase C1q PF00386.16 KND98138.1 - 0.01 15.8 0.0 4.1 7.4 0.0 2.7 2 0 0 2 2 2 2 C1q domain Cupredoxin_1 PF13473.1 KND98138.1 - 0.078 12.8 0.0 21 5.0 0.0 3.1 3 0 0 3 3 3 0 Cupredoxin-like domain ACCA PF03255.9 KND98140.1 - 0.11 12.0 12.7 1.2 8.6 1.9 2.8 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Spc7 PF08317.6 KND98140.1 - 0.11 11.0 22.1 0.2 10.2 15.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Tup_N PF08581.5 KND98140.1 - 1.7 8.8 19.7 0.053 13.7 8.0 2.6 2 1 0 2 2 2 0 Tup N-terminal Myb_DNA-bind_6 PF13921.1 KND98141.1 - 1.6e-20 72.9 8.4 8.3e-14 51.4 1.3 3.7 3 1 1 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KND98141.1 - 1.7e-18 66.3 10.2 1.3e-09 37.9 0.6 4.2 5 0 0 5 5 5 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KND98141.1 - 0.00065 19.7 12.8 0.0013 18.7 1.1 3.6 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 KND98141.1 - 0.031 14.4 6.6 1.2 9.4 2.3 3.2 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Sec5 PF15469.1 KND98142.1 - 1.7e-37 128.9 14.2 1.7e-37 128.9 9.9 3.5 3 1 0 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.6 KND98142.1 - 0.0014 18.3 1.7 0.0014 18.3 1.2 3.8 3 0 0 3 3 3 1 Vps51/Vps67 FTR1 PF03239.9 KND98143.1 - 1.1e-95 320.1 7.1 1.3e-95 319.8 4.9 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Malectin_like PF12819.2 KND98143.1 - 0.061 12.3 0.0 0.083 11.9 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate-binding protein of the ER PrgI PF12666.2 KND98143.1 - 0.52 10.4 13.1 0.24 11.5 1.4 3.5 3 1 0 3 3 3 0 PrgI family protein Alba PF01918.16 KND98146.1 - 4.2e-09 35.8 1.2 7.1e-09 35.1 0.3 1.8 2 0 0 2 2 2 1 Alba Pep_deformylase PF01327.16 KND98146.1 - 0.08 12.3 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Polypeptide deformylase DUF814 PF05670.8 KND98148.1 - 2.6e-18 65.6 0.2 5.1e-18 64.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF814) RabGAP-TBC PF00566.13 KND98150.1 - 3.9e-33 114.7 6.1 6.5e-33 114.0 4.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Not1 PF04054.10 KND98152.1 - 5.6e-114 380.9 1.0 1.3e-113 379.7 0.7 1.7 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 KND98152.1 - 2.8e-35 121.1 3.7 9e-35 119.5 2.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) DUF3802 PF12290.3 KND98152.1 - 0.0078 16.5 0.9 0.12 12.6 0.0 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF3802) UQ_con PF00179.21 KND98153.1 - 1.5e-42 144.3 0.1 2e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 KND98153.1 - 1.7e-19 69.1 0.1 3.3e-19 68.2 0.1 1.5 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 KND98153.1 - 3.5e-07 30.0 0.0 5.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KND98153.1 - 0.095 12.6 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 RWD domain GN3L_Grn1 PF08701.6 KND98153.1 - 0.26 11.2 1.0 0.65 9.9 0.7 1.6 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase DBR1 PF05011.8 KND98154.1 - 9.2e-18 64.5 0.1 1.9e-17 63.4 0.1 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 KND98154.1 - 0.00013 21.4 0.1 0.00037 19.9 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase NAD_binding_1 PF00175.16 KND98155.1 - 1.3e-28 99.6 0.0 2.8e-28 98.6 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KND98155.1 - 5.5e-19 68.1 0.0 9.9e-19 67.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KND98155.1 - 1.5e-05 24.9 0.0 0.00034 20.5 0.0 2.3 1 1 0 2 2 2 1 Ferric reductase NAD binding domain Carb_kinase PF01256.12 KND98156.1 - 2.4e-48 164.5 0.0 2.7e-47 161.1 0.0 1.9 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 KND98156.1 - 0.00015 21.0 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF3994 PF13159.1 KND98157.1 - 0.84 9.9 6.2 1.2 9.4 1.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) Med15 PF09606.5 KND98157.1 - 2.1 6.4 41.2 2.8 6.0 28.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal NAD_Gly3P_dh_N PF01210.18 KND98159.1 - 1.8e-51 173.9 0.1 3.2e-51 173.1 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 KND98159.1 - 3.2e-39 134.0 0.0 6.3e-39 133.0 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 KND98159.1 - 0.0076 16.6 0.1 0.1 13.0 0.1 2.3 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NUDIX PF00293.23 KND98160.1 - 1.5e-09 37.6 0.1 4.7e-09 35.9 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain Rota_VP2 PF05087.7 KND98161.1 - 0.19 9.6 1.8 0.21 9.4 1.2 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein FliT PF05400.8 KND98161.1 - 0.43 11.0 2.5 2.4 8.6 0.0 2.6 3 0 0 3 3 3 0 Flagellar protein FliT Brix PF04427.13 KND98162.1 - 2.4e-54 183.9 1.3 3.5e-54 183.3 0.9 1.2 1 0 0 1 1 1 1 Brix domain TT_ORF2 PF02957.10 KND98162.1 - 0.071 13.8 4.5 0.14 12.8 3.1 1.4 1 0 0 1 1 1 0 TT viral ORF2 AIF_C PF14721.1 KND98162.1 - 0.14 12.4 2.3 0.16 12.1 0.8 1.8 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term NARP1 PF12569.3 KND98162.1 - 0.32 9.7 11.8 0.49 9.0 8.2 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FGF-BP1 PF06473.7 KND98162.1 - 0.59 9.6 8.4 0.71 9.4 5.2 1.6 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) DEAD PF00270.24 KND98163.1 - 3.9e-47 159.8 0.0 1.3e-46 158.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND98163.1 - 8.5e-27 92.8 0.0 1.8e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND98163.1 - 5.3e-05 23.1 0.0 0.00094 19.0 0.0 2.8 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.1 KND98164.1 - 2.2e-12 46.6 6.7 7.1e-12 44.9 1.6 2.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 KND98164.1 - 2.8e-06 27.2 5.8 1.1e-05 25.2 2.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KND98164.1 - 9.2e-05 22.0 3.5 0.00032 20.3 1.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KND98164.1 - 0.00018 21.5 4.4 0.00081 19.4 1.5 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KND98164.1 - 0.0012 18.5 4.0 0.027 14.2 1.6 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KND98164.1 - 0.0022 17.5 2.9 0.078 12.6 0.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KND98164.1 - 0.019 14.6 1.5 0.019 14.6 1.0 2.1 2 0 0 2 2 2 0 RING-type zinc-finger RINGv PF12906.2 KND98164.1 - 0.021 14.8 2.6 0.021 14.8 1.8 1.9 2 0 0 2 2 2 0 RING-variant domain Atracotoxin PF05353.6 KND98164.1 - 0.082 12.7 0.7 0.22 11.3 0.5 1.6 1 0 0 1 1 1 0 Delta Atracotoxin zf-Apc11 PF12861.2 KND98164.1 - 0.11 12.3 0.9 0.35 10.7 0.4 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 KND98164.1 - 0.33 10.7 7.0 2.9 7.7 2.4 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF2175 PF09943.4 KND98164.1 - 2.1 8.4 4.9 0.64 10.1 1.3 1.7 2 0 0 2 2 1 0 Uncharacterized protein conserved in archaea (DUF2175) AA_permease PF00324.16 KND98165.1 - 7.4e-92 308.1 44.0 9.1e-92 307.8 30.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND98165.1 - 1.8e-27 95.9 51.3 2.4e-27 95.5 35.5 1.2 1 0 0 1 1 1 1 Amino acid permease Med21 PF11221.3 KND98166.1 - 2e-46 157.5 0.8 2.5e-46 157.2 0.5 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Spore_III_AB PF09548.5 KND98166.1 - 0.05 13.3 0.2 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) TACC PF05010.9 KND98166.1 - 0.19 11.4 3.1 0.25 11.0 2.1 1.7 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Med2 PF11214.3 KND98166.1 - 0.8 9.7 3.8 0.94 9.5 0.0 2.3 2 1 0 2 2 2 0 Mediator complex subunit 2 PMT PF02366.13 KND98167.1 - 8.9e-63 211.8 16.3 8.9e-63 211.8 11.3 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KND98167.1 - 2e-22 79.6 1.6 3e-22 79.0 1.1 1.3 1 0 0 1 1 1 1 MIR domain Ins145_P3_rec PF08709.6 KND98167.1 - 0.058 12.4 0.8 0.63 9.0 0.2 2.0 1 1 1 2 2 2 0 Inositol 1,4,5-trisphosphate/ryanodine receptor DUF2518 PF10726.4 KND98167.1 - 2.4 7.7 6.5 0.22 11.0 0.7 2.1 2 0 0 2 2 2 0 Protein of function (DUF2518) Med19 PF10278.4 KND98170.1 - 0.0055 16.3 2.8 0.0065 16.1 1.9 1.2 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 BNIP3 PF06553.7 KND98170.1 - 0.14 11.5 4.1 0.17 11.2 2.8 1.1 1 0 0 1 1 1 0 BNIP3 Peptidase_S49_N PF08496.5 KND98170.1 - 1.1 9.0 4.1 1.3 8.7 2.9 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Rsm22 PF09243.5 KND98172.1 - 9.9e-24 83.8 1.8 5.8e-10 38.6 1.3 4.2 2 2 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.1 KND98172.1 - 0.001 18.8 0.0 0.0059 16.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain ApoO PF09769.4 KND98173.1 - 6.1e-46 156.0 0.0 1e-45 155.2 0.0 1.4 1 0 0 1 1 1 1 Apolipoprotein O ARA70 PF12489.3 KND98173.1 - 0.0043 17.0 0.0 0.0081 16.1 0.0 1.4 1 0 0 1 1 1 1 Nuclear coactivator FANCI_S4 PF14678.1 KND98174.1 - 0.042 12.9 0.6 0.066 12.3 0.4 1.3 1 0 0 1 1 1 0 FANCI solenoid 4 Mito_carr PF00153.22 KND98175.1 - 2.1e-60 200.4 4.3 1.1e-24 85.8 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein PsaL PF02605.10 KND98175.1 - 0.056 12.9 0.1 0.18 11.3 0.1 1.8 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI Raptor_N PF14538.1 KND98177.1 - 9.2e-68 226.9 0.0 1.7e-67 226.0 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 KND98177.1 - 1.7e-10 40.3 2.9 0.59 10.1 0.0 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat HEAT PF02985.17 KND98177.1 - 5.3e-06 26.0 1.5 0.51 10.5 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 KND98177.1 - 0.0098 16.1 0.0 0.23 11.7 0.0 2.9 2 0 0 2 2 2 1 HEAT repeats Cnd1 PF12717.2 KND98177.1 - 0.024 14.4 0.1 6.5 6.5 0.0 2.8 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Prp19_bind PF06991.6 KND98180.1 - 2.1e-10 40.3 15.3 4.2e-06 26.2 5.4 3.0 2 1 1 3 3 3 3 Splicing factor, Prp19-binding domain DUF4412 PF14371.1 KND98180.1 - 0.06 13.8 0.8 3 8.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4412) V4R PF02830.13 KND98181.1 - 0.13 12.1 0.1 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 V4R domain CDO_I PF05995.7 KND98182.1 - 1.9e-39 134.6 0.0 2.4e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 KND98182.1 - 0.00084 18.7 0.5 0.015 14.6 0.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) SLAC1 PF03595.12 KND98183.1 - 2.1e-77 259.9 43.9 2.4e-77 259.7 30.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF202 PF02656.10 KND98183.1 - 8.9 6.6 18.3 1.9 8.7 0.6 4.5 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Trs65 PF12735.2 KND98185.1 - 4e-63 213.5 10.9 4e-63 213.5 7.6 2.0 2 1 0 2 2 2 1 TRAPP trafficking subunit Trs65 TFIID_30kDa PF03540.8 KND98187.1 - 2.5e-27 94.4 0.1 5.8e-27 93.2 0.0 1.7 2 0 0 2 2 2 1 Transcription initiation factor TFIID 23-30kDa subunit WD40 PF00400.27 KND98188.1 - 9.2e-10 38.0 16.2 0.0012 18.6 0.0 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat zf-C3HC4_2 PF13923.1 KND98188.1 - 0.11 12.5 10.1 0.33 11.0 7.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) adh_short PF00106.20 KND98189.1 - 0.00076 19.4 0.0 0.0086 16.0 0.0 2.4 1 1 0 1 1 1 1 short chain dehydrogenase MFS_1 PF07690.11 KND98191.1 - 1.4e-36 125.9 16.9 1.4e-36 125.9 11.7 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily HECT PF00632.20 KND98192.1 - 2e-75 253.8 0.2 2e-75 253.8 0.1 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) RIX1 PF08167.7 KND98192.1 - 0.0086 15.7 0.7 0.17 11.5 0.1 2.8 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Daxx PF03344.10 KND98192.1 - 1.3 7.4 24.0 0.79 8.1 13.6 2.0 2 0 0 2 2 2 0 Daxx Family F-actin_cap_A PF01267.12 KND98193.1 - 4.2e-51 173.5 0.9 5e-51 173.3 0.6 1.1 1 0 0 1 1 1 1 F-actin capping protein alpha subunit HSCB_C PF07743.8 KND98193.1 - 0.012 16.0 0.4 0.17 12.3 0.0 2.5 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain CDC14 PF08045.6 KND98193.1 - 0.036 13.1 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 Cell division control protein 14, SIN component DUF4520 PF15016.1 KND98193.1 - 0.057 13.0 0.1 0.3 10.6 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4520) Sec20 PF03908.8 KND98195.1 - 0.02 14.5 0.3 0.046 13.4 0.2 1.6 1 1 0 1 1 1 0 Sec20 Syntaxin_2 PF14523.1 KND98195.1 - 0.03 14.3 2.4 0.037 14.0 1.7 1.1 1 0 0 1 1 1 0 Syntaxin-like protein Prominin PF05478.6 KND98195.1 - 0.042 11.4 0.1 0.052 11.0 0.0 1.2 1 0 0 1 1 1 0 Prominin PilJ PF13675.1 KND98195.1 - 0.047 13.9 0.2 0.054 13.8 0.1 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term ApoC-I PF04691.7 KND98195.1 - 0.063 12.9 0.3 0.17 11.5 0.2 1.8 1 1 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) DDE_Tnp_1_7 PF13843.1 KND98195.1 - 0.086 11.8 0.2 0.095 11.7 0.2 1.1 1 0 0 1 1 1 0 Transposase IS4 DASH_Dad4 PF08650.5 KND98195.1 - 0.18 11.7 1.9 1.5 8.7 0.0 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad4 VHS PF00790.14 KND98196.1 - 1.3e-28 99.3 0.7 1.3e-28 99.3 0.5 2.0 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.23 KND98196.1 - 1.1e-15 56.7 0.0 1.9e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KND98196.1 - 2.6e-14 52.4 0.1 5.2e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KND98196.1 - 5.7e-13 48.1 0.0 1e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 KND98196.1 - 0.14 11.8 4.1 0.4 10.3 2.8 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Tn7_Tnp_TnsA_C PF08721.6 KND98196.1 - 0.21 11.6 2.1 11 6.0 0.0 3.9 5 0 0 5 5 5 0 TnsA endonuclease C terminal TRAM_LAG1_CLN8 PF03798.11 KND98197.1 - 1.6e-32 112.7 22.1 1.6e-32 112.7 15.3 2.3 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KND98197.1 - 5.9e-21 73.7 0.3 5.9e-21 73.7 0.2 2.2 2 0 0 2 2 2 1 TRAM1-like protein Ribosomal_S2 PF00318.15 KND98198.1 - 4.1e-57 192.8 0.2 2.6e-55 186.9 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein S2 DUF4200 PF13863.1 KND98198.1 - 3.5 7.5 14.6 1.1 9.2 8.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) CS PF04969.11 KND98199.1 - 8.6e-09 35.8 0.0 1.5e-08 35.0 0.0 1.5 1 1 0 1 1 1 1 CS domain Syja_N PF02383.13 KND98201.1 - 8.7e-90 300.7 2.3 1.6e-89 299.8 0.1 2.3 2 0 0 2 2 2 1 SacI homology domain DUF1626 PF07788.6 KND98201.1 - 0.063 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1626) SNF5 PF04855.7 KND98203.1 - 3.5e-58 196.9 3.0 4.6e-56 190.0 2.1 2.2 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GIDA_assoc_3 PF13932.1 KND98203.1 - 0.099 12.7 1.1 4.4 7.4 0.0 3.3 3 0 0 3 3 3 0 GidA associated domain 3 dCMP_cyt_deam_1 PF00383.17 KND98205.1 - 2.1e-07 30.5 0.1 3.2e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Telomerase_RBD PF12009.3 KND98206.1 - 6.5e-21 74.6 3.7 2.1e-20 73.0 2.6 1.9 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 KND98206.1 - 2.7e-13 49.7 0.2 2.5e-12 46.6 0.1 2.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1128 PF06569.6 KND98206.1 - 0.05 13.3 0.1 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) AIP3 PF03915.8 KND98207.1 - 2.4e-128 428.6 12.9 2.4e-128 428.6 8.9 2.1 2 0 0 2 2 2 1 Actin interacting protein 3 FliL PF03748.9 KND98207.1 - 0.0065 16.4 0.7 0.044 13.7 0.1 2.7 2 0 0 2 2 2 1 Flagellar basal body-associated protein FliL Laminin_II PF06009.7 KND98207.1 - 0.025 14.3 5.4 0.03 14.0 1.8 2.6 2 0 0 2 2 2 0 Laminin Domain II Syntaxin_2 PF14523.1 KND98207.1 - 0.082 12.9 0.1 0.082 12.9 0.1 4.0 5 1 0 5 5 5 0 Syntaxin-like protein Cob_adeno_trans PF01923.13 KND98207.1 - 0.4 10.4 4.7 1.3 8.7 0.0 3.4 4 1 1 5 5 5 0 Cobalamin adenosyltransferase DUF948 PF06103.6 KND98207.1 - 0.67 9.8 9.4 26 4.7 0.0 4.8 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF948) MitMem_reg PF13012.1 KND98207.1 - 1 9.4 6.8 1 9.4 0.3 4.1 4 1 2 6 6 6 0 Maintenance of mitochondrial structure and function Baculo_PEP_C PF04513.7 KND98207.1 - 2.5 7.9 13.4 0.094 12.5 1.0 4.0 5 1 0 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus HEAT_2 PF13646.1 KND98208.1 - 1.5e-15 57.2 5.8 3.6e-05 23.9 0.0 6.6 5 1 1 6 6 6 3 HEAT repeats HEAT_EZ PF13513.1 KND98208.1 - 6.3e-11 42.4 26.6 0.00039 20.8 0.1 10.3 7 2 5 12 12 12 4 HEAT-like repeat MMS19_C PF12460.3 KND98208.1 - 5e-06 25.5 15.4 0.0013 17.5 1.6 4.9 4 1 1 5 5 5 2 RNAPII transcription regulator C-terminal HEAT PF02985.17 KND98208.1 - 1.6e-05 24.5 28.8 0.00039 20.2 0.0 9.6 12 0 0 12 12 12 2 HEAT repeat Arm PF00514.18 KND98208.1 - 2.7e-05 23.8 8.2 0.002 17.8 0.0 5.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 KND98208.1 - 0.00016 21.9 0.6 0.31 11.4 0.0 5.5 4 2 1 5 5 5 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.3 KND98208.1 - 0.0025 17.7 0.4 1.4 8.8 0.0 4.5 5 1 0 6 6 6 1 Domain of unknown function (DUF3385) ParcG PF10274.4 KND98208.1 - 0.0059 16.5 0.9 0.87 9.4 0.0 4.1 4 1 1 5 5 5 1 Parkin co-regulated protein M11L PF11099.3 KND98208.1 - 0.039 13.6 0.7 0.21 11.2 0.2 2.4 1 1 1 2 2 2 0 Apoptosis regulator M11L like TGS PF02824.16 KND98209.1 - 2.8e-21 75.1 0.1 5.3e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KND98209.1 - 8.5e-19 67.6 0.4 2.2e-18 66.3 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KND98209.1 - 7.9e-10 38.2 0.1 1.8e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KND98209.1 - 0.00049 19.9 0.7 0.28 10.9 0.0 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 KND98209.1 - 0.0011 18.3 0.9 0.46 9.8 0.6 3.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 KND98209.1 - 0.0016 17.2 0.6 0.0088 14.8 0.2 2.1 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 KND98209.1 - 0.027 14.9 0.1 0.12 12.9 0.0 2.1 1 1 0 2 2 2 0 Miro-like protein GTP_EFTU PF00009.22 KND98210.1 - 7.6e-32 110.2 0.0 3.7e-31 108.0 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KND98210.1 - 9.1e-22 77.0 0.0 3e-21 75.3 0.0 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KND98210.1 - 3.1e-11 43.2 1.0 5.8e-08 32.7 0.0 3.0 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KND98210.1 - 1.9e-06 27.8 0.1 8.5e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KND98210.1 - 0.00047 19.7 0.2 0.0034 16.9 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 KND98210.1 - 0.01 15.9 0.1 0.058 13.5 0.1 2.3 1 1 0 1 1 1 0 AAA domain GTP_EFTU_D4 PF14578.1 KND98210.1 - 0.035 13.7 0.1 0.1 12.2 0.0 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 4 GRIM-19 PF06212.7 KND98211.1 - 5.2e-20 71.4 0.0 5.8e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 GRIM-19 protein Hydrolase_6 PF13344.1 KND98212.1 - 2.1e-28 98.1 0.0 5e-28 96.9 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KND98212.1 - 2.7e-17 62.2 0.0 5.3e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KND98212.1 - 9.8e-12 45.7 0.0 1.4e-09 38.7 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KND98212.1 - 0.00019 21.7 1.7 0.72 10.0 0.1 3.2 3 1 0 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 KND98212.1 - 0.05 12.9 0.0 0.77 9.0 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Hpt PF01627.18 KND98213.1 - 2.4e-10 40.2 0.0 3.2e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Hpt domain FbpA PF05833.6 KND98213.1 - 0.0051 15.4 0.2 0.0054 15.3 0.1 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NADPH_Ox PF08414.5 KND98213.1 - 0.093 12.8 0.4 0.34 11.0 0.1 1.8 1 1 1 2 2 2 0 Respiratory burst NADPH oxidase Glyco_transf_22 PF03901.12 KND98214.1 - 7.2e-76 255.8 31.9 9.1e-76 255.5 22.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Adenylsucc_synt PF00709.16 KND98215.1 - 6.5e-167 555.4 0.0 7.4e-167 555.2 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase NA37 PF04245.8 KND98215.1 - 0.026 13.8 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein Complex1_LYR_2 PF13233.1 KND98217.1 - 9.1e-14 51.8 4.9 1.3e-13 51.2 3.4 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Blo-t-5 PF11642.3 KND98217.1 - 0.044 13.5 5.8 0.029 14.1 2.5 1.7 1 1 1 2 2 2 0 Mite allergen Blo t 5 DAO PF01266.19 KND98217.1 - 0.071 12.0 0.1 0.077 11.8 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase PolyG_pol PF01518.11 KND98217.1 - 0.08 11.4 0.1 0.097 11.1 0.1 1.1 1 0 0 1 1 1 0 Sigma NS protein Bcr-Abl_Oligo PF09036.5 KND98217.1 - 0.56 10.2 5.9 0.68 9.9 3.0 1.8 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain BLVR PF06375.6 KND98219.1 - 1.9 8.2 10.6 1.8 8.3 7.3 1.0 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Med19 PF10278.4 KND98219.1 - 4.3 6.9 10.3 4.2 6.9 7.1 1.0 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Peptidase_S49_N PF08496.5 KND98219.1 - 6 6.6 6.6 5.8 6.6 4.6 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ERK-JNK_inhib PF15002.1 KND98219.1 - 7.3 5.8 8.7 7.4 5.8 6.1 1.0 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor FUN14 PF04930.10 KND98220.1 - 1.6e-07 31.4 0.9 7.2e-07 29.4 0.7 1.9 1 1 0 1 1 1 1 FUN14 family RNA_pol_Rpb1_5 PF04998.12 KND98221.1 - 2.1e-94 315.8 0.0 7.6e-94 314.0 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KND98221.1 - 2.1e-63 213.2 0.1 4.3e-63 212.1 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KND98221.1 - 6.2e-40 136.5 0.0 3.7e-39 133.9 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 KND98221.1 - 1.1e-24 87.3 0.2 2.3e-20 73.1 0.0 3.0 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 KND98221.1 - 5.2e-22 77.6 1.1 1.6e-21 76.0 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Glycos_transf_4 PF00953.16 KND98222.1 - 1.5e-28 99.5 15.4 1.5e-28 99.5 10.6 2.9 3 2 0 3 3 3 1 Glycosyl transferase family 4 WD40 PF00400.27 KND98223.1 - 1.1e-32 110.6 9.6 7e-08 32.0 0.0 5.5 6 0 0 6 6 6 5 WD domain, G-beta repeat WD40 PF00400.27 KND98224.1 - 8.6e-06 25.4 0.0 9.2e-05 22.1 0.0 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat HSP70 PF00012.15 KND98226.1 - 1.8e-70 237.5 2.8 3.9e-70 236.4 0.9 1.9 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 KND98226.1 - 7.4e-06 24.7 0.0 1.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein RabGAP-TBC PF00566.13 KND98227.1 - 2.3e-47 161.2 3.5 2.3e-46 157.9 2.4 2.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain THF_DHG_CYH PF00763.18 KND98228.1 - 9.2e-21 74.0 0.0 1.6e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 KND98228.1 - 5.6e-18 64.5 0.0 7.9e-12 44.5 0.0 2.8 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.19 KND98228.1 - 0.012 15.8 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KND98228.1 - 0.034 14.2 0.1 2.4 8.2 0.0 2.2 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Biopterin_H PF00351.16 KND98229.1 - 0.16 10.6 0.0 0.2 10.4 0.0 1.0 1 0 0 1 1 1 0 Biopterin-dependent aromatic amino acid hydroxylase Myb_DNA-bind_6 PF13921.1 KND98230.1 - 1.9e-31 107.9 8.6 3.3e-13 49.5 1.6 3.7 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KND98230.1 - 1.1e-25 89.3 23.6 1.1e-11 44.6 0.6 3.8 4 0 0 4 4 4 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 KND98230.1 - 0.0051 16.9 8.3 1 9.6 0.5 3.7 1 1 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like UCH PF00443.24 KND98232.1 - 2.1e-47 161.5 0.1 4e-47 160.5 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KND98232.1 - 3.3e-19 69.4 0.1 7.5e-19 68.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Kin17_mid PF10357.4 KND98233.1 - 6.6e-35 119.5 1.5 1.1e-34 118.7 1.1 1.3 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 KND98233.1 - 3.8e-06 26.8 1.8 8.7e-06 25.7 1.2 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KND98233.1 - 9.8e-05 22.4 1.7 0.00022 21.3 1.1 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KND98233.1 - 0.026 14.6 3.0 0.044 13.8 0.1 2.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KND98233.1 - 0.046 14.0 1.5 0.094 13.0 1.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KND98233.1 - 0.17 12.3 1.6 0.48 10.8 1.1 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type Peptidase_M48 PF01435.13 KND98235.1 - 2.8e-28 99.0 0.0 5e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 SKG6 PF08693.5 KND98236.1 - 0.0047 16.2 0.0 0.012 14.9 0.0 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.1 KND98236.1 - 0.0058 16.3 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 Transmembrane protein 51 Coa1 PF08695.5 KND98238.1 - 6.1e-40 135.3 0.0 1.1e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 ODC_AZ PF02100.12 KND98239.1 - 0.052 13.0 0.1 0.052 13.0 0.1 1.1 1 0 0 1 1 1 0 Ornithine decarboxylase antizyme Alb1 PF09135.6 KND98240.1 - 1.1e-12 48.5 7.6 1.1e-12 48.5 5.3 1.7 2 1 1 3 3 3 1 Alb1 Ribosomal_S13 PF00416.17 KND98240.1 - 0.087 13.2 1.1 0.087 13.2 0.8 1.8 1 1 1 2 2 2 0 Ribosomal protein S13/S18 DUF2099 PF09872.4 KND98240.1 - 0.14 11.1 0.4 0.16 10.9 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2099) V_ATPase_I PF01496.14 KND98240.1 - 2.7 5.7 7.1 3.2 5.5 4.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Calreticulin PF00262.13 KND98241.1 - 1.3e-130 435.3 6.3 1.7e-130 434.9 4.4 1.2 1 0 0 1 1 1 1 Calreticulin family Exo_endo_phos PF03372.18 KND98243.1 - 2.2e-13 50.7 0.2 2.9e-13 50.3 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KND98243.1 - 0.0051 16.4 0.1 0.13 11.9 0.0 2.4 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase DUF3574 PF12098.3 KND98245.1 - 0.062 12.8 0.1 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) Sugar_tr PF00083.19 KND98250.1 - 1e-33 116.6 19.9 1.4e-33 116.1 13.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND98250.1 - 1.5e-32 112.6 23.0 1.5e-32 112.6 15.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRAPPC10 PF12584.3 KND98253.1 - 2.4e-28 98.4 0.2 4.3e-28 97.6 0.1 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.2 KND98253.1 - 0.046 13.5 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking CUE PF02845.11 KND98257.1 - 0.00024 20.5 0.0 0.00055 19.3 0.0 1.7 1 0 0 1 1 1 1 CUE domain AgrB PF04647.10 KND98257.1 - 0.13 11.3 0.9 0.19 10.7 0.1 1.6 2 0 0 2 2 2 0 Accessory gene regulator B Pribosyl_synth PF14572.1 KND98258.1 - 2.7e-36 125.0 0.1 4.3e-36 124.3 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KND98258.1 - 7.8e-35 119.1 0.1 6.7e-34 116.1 0.0 2.4 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KND98258.1 - 8.1e-12 44.9 0.1 2e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Adap_comp_sub PF00928.16 KND98259.1 - 2e-68 230.3 0.0 2.4e-68 230.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KND98259.1 - 0.0034 17.1 0.0 0.017 14.8 0.0 2.0 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Kisspeptin PF15152.1 KND98260.1 - 0.33 11.6 7.6 0.35 11.5 0.0 3.3 3 1 1 4 4 4 0 Kisspeptin ELFV_dehydrog PF00208.16 KND98269.1 - 9.1e-64 215.3 0.1 1.2e-63 214.9 0.1 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 KND98269.1 - 2.9e-15 54.8 0.1 8.7e-09 33.4 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 KND98269.1 - 0.0011 18.5 0.0 0.0031 17.1 0.0 1.7 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ABG_transport PF03806.8 KND98270.1 - 0.0068 14.4 0.0 0.0068 14.4 0.0 1.0 1 0 0 1 1 1 1 AbgT putative transporter family WD40 PF00400.27 KND98271.1 - 0.0035 17.1 5.7 2 8.4 0.1 4.9 5 1 0 5 5 5 2 WD domain, G-beta repeat PQQ_2 PF13360.1 KND98271.1 - 0.088 12.2 0.2 1.2 8.5 0.0 2.1 1 1 1 2 2 2 0 PQQ-like domain PQQ PF01011.16 KND98271.1 - 0.14 11.7 0.3 1.9 8.1 0.0 2.8 3 0 0 3 3 3 0 PQQ enzyme repeat Frataxin_Cyay PF01491.11 KND98277.1 - 3.6e-36 123.2 0.0 4.5e-36 122.9 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain PTR2 PF00854.16 KND98279.1 - 1.9e-54 184.8 15.6 2.5e-54 184.5 10.8 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.11 KND98279.1 - 4.5e-05 22.3 25.8 0.00045 19.0 4.2 3.1 2 1 2 4 4 4 2 Major Facilitator Superfamily Rop-like PF05082.8 KND98280.1 - 0.39 10.2 0.1 0.39 10.2 0.0 2.0 2 0 0 2 2 2 0 Rop-like Bravo_FIGEY PF13882.1 KND98280.1 - 2 9.3 6.9 0.26 12.2 1.0 1.9 1 1 1 2 2 2 0 Bravo-like intracellular region PPR_1 PF12854.2 KND98281.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 PPR repeat PPR_2 PF13041.1 KND98281.1 - 0.14 12.1 0.2 15 5.6 0.0 2.9 3 0 0 3 3 3 0 PPR repeat family MRP-S25 PF13741.1 KND98282.1 - 5e-83 278.1 5.0 5.8e-83 277.9 3.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 HipA_N PF07805.7 KND98282.1 - 0.13 12.4 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 HipA-like N-terminal domain NDUF_B12 PF08122.7 KND98283.1 - 1.5e-16 59.8 0.1 1.7e-16 59.6 0.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Vmethyltransf_C PF08456.5 KND98285.1 - 0.14 11.4 0.1 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Viral methyltransferase C-terminal DUF1771 PF08590.5 KND98286.1 - 1.7e-21 75.9 11.7 2.9e-21 75.2 8.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 KND98286.1 - 4.2e-17 62.0 0.2 4.2e-17 62.0 0.1 2.4 3 0 0 3 3 3 1 Smr domain MitMem_reg PF13012.1 KND98286.1 - 0.059 13.4 2.3 0.12 12.4 1.6 1.5 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function Bromodomain PF00439.20 KND98286.1 - 0.1 12.5 0.4 0.2 11.5 0.3 1.6 1 1 0 1 1 1 0 Bromodomain Seryl_tRNA_N PF02403.17 KND98286.1 - 0.37 10.8 8.5 0.4 10.7 5.0 1.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ras PF00071.17 KND98287.1 - 2.5e-52 176.5 0.1 3.1e-52 176.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KND98287.1 - 4.7e-20 72.2 0.0 7e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KND98287.1 - 1.5e-14 53.5 0.1 1.9e-14 53.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KND98287.1 - 5.1e-08 32.3 0.1 6.5e-08 31.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KND98287.1 - 3.2e-07 29.9 0.0 4.6e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KND98287.1 - 9.9e-06 25.5 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KND98287.1 - 6e-05 22.6 0.2 0.0092 15.5 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 KND98287.1 - 0.00013 22.0 0.0 0.00074 19.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 KND98287.1 - 0.00037 19.7 0.1 0.00054 19.2 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 KND98287.1 - 0.00085 19.0 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase MobB PF03205.9 KND98287.1 - 0.0015 18.2 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 KND98287.1 - 0.002 17.7 0.1 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KND98287.1 - 0.0028 17.1 0.3 0.0073 15.8 0.1 1.9 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 KND98287.1 - 0.003 16.7 0.0 0.0066 15.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NACHT PF05729.7 KND98287.1 - 0.0033 17.1 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KND98287.1 - 0.0041 17.1 0.1 0.011 15.7 0.0 1.8 2 1 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.10 KND98287.1 - 0.0079 15.9 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 NTPase Septin PF00735.13 KND98287.1 - 0.013 14.5 0.1 0.029 13.3 0.1 1.6 1 0 0 1 1 1 0 Septin AAA_10 PF12846.2 KND98287.1 - 0.032 13.6 0.1 0.044 13.2 0.1 1.3 1 1 0 1 1 1 0 AAA-like domain Glyco_hydro_70 PF02324.11 KND98287.1 - 0.036 11.8 0.0 0.044 11.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 NB-ARC PF00931.17 KND98287.1 - 0.043 12.6 0.1 0.064 12.1 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.9 KND98287.1 - 0.044 13.5 0.1 0.18 11.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 KND98287.1 - 0.045 13.2 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_tran PF00005.22 KND98287.1 - 0.051 13.8 0.1 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter PRK PF00485.13 KND98287.1 - 0.052 13.1 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.15 KND98287.1 - 0.071 11.7 1.8 0.12 11.0 1.2 1.8 1 1 0 1 1 1 0 G-protein alpha subunit AAA_14 PF13173.1 KND98287.1 - 0.073 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KND98287.1 - 0.094 12.9 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase CBS PF00571.23 KND98288.1 - 8.4e-22 76.7 0.0 8.8e-08 31.8 0.0 4.3 4 0 0 4 4 4 4 CBS domain FA_desaturase PF00487.19 KND98292.1 - 5.4e-16 58.8 17.8 5.4e-16 58.8 12.3 1.5 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 KND98292.1 - 6.7e-13 48.2 0.0 1.6e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain GP41 PF00517.12 KND98292.1 - 0.061 12.8 0.1 0.061 12.8 0.1 1.7 2 0 0 2 2 2 0 Retroviral envelope protein Flu_M2 PF00599.12 KND98296.1 - 0.013 15.2 0.2 0.016 14.9 0.2 1.1 1 0 0 1 1 1 0 Influenza Matrix protein (M2) ADH_zinc_N PF00107.21 KND98298.1 - 5.2e-32 110.1 1.3 7.7e-32 109.5 0.9 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KND98298.1 - 3e-30 104.1 0.1 6.8e-30 103.0 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KND98298.1 - 2.9e-05 24.9 0.2 6.8e-05 23.7 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Transketolase_N PF00456.16 KND98299.1 - 5.7e-154 511.8 0.0 7.5e-154 511.4 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KND98299.1 - 1.3e-46 158.2 0.0 2.3e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KND98299.1 - 8.1e-10 38.7 0.0 2.2e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 KND98299.1 - 4.6e-08 32.3 0.0 1e-06 27.8 0.0 2.2 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 KND98299.1 - 7.8e-05 21.5 0.0 0.00013 20.8 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KND98299.1 - 0.011 15.3 0.2 0.1 12.1 0.1 2.4 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Terpene_synth PF01397.16 KND98299.1 - 0.039 13.3 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain VWA_2 PF13519.1 KND98299.1 - 0.11 12.6 0.2 0.6 10.2 0.0 2.2 2 1 0 2 2 2 0 von Willebrand factor type A domain OB_RNB PF08206.6 KND98303.1 - 0.1 12.1 0.5 0.18 11.3 0.1 1.6 2 0 0 2 2 2 0 Ribonuclease B OB domain Not3 PF04065.10 KND98304.1 - 6.2e-81 271.0 21.6 6.2e-81 271.0 14.9 1.5 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 KND98304.1 - 9.7e-30 103.1 3.4 9.7e-30 103.1 2.4 1.9 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF605 PF04652.11 KND98304.1 - 0.09 12.1 21.6 0.16 11.3 14.9 1.5 1 0 0 1 1 1 0 Vta1 like Mnd1 PF03962.10 KND98304.1 - 1.3 8.6 14.7 1.4 8.5 5.9 2.6 1 1 1 2 2 2 0 Mnd1 family LMWPc PF01451.16 KND98305.1 - 1.4e-27 96.7 0.0 1.6e-27 96.5 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Med15_fungi PF05397.7 KND98306.1 - 9.6e-28 96.4 2.5 9.6e-28 96.4 1.7 4.1 6 0 0 6 6 6 1 Mediator complex subunit 15 KIX PF02172.11 KND98306.1 - 0.0046 16.9 0.9 0.01 15.8 0.1 2.1 2 0 0 2 2 2 1 KIX domain WD40 PF00400.27 KND98307.1 - 2.4e-71 233.2 26.4 9.7e-09 34.7 0.9 11.7 12 0 0 12 12 12 11 WD domain, G-beta repeat Utp12 PF04003.7 KND98307.1 - 3.3e-21 75.2 1.2 7.9e-21 74.0 0.8 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 KND98307.1 - 9e-13 47.2 1.7 0.00043 18.5 0.1 5.0 5 0 0 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KND98307.1 - 7.9e-06 24.8 9.6 0.078 11.7 0.0 6.4 3 2 3 7 7 7 3 Nup133 N terminal like PLA2_B PF01735.13 KND98308.1 - 1.1e-172 574.6 0.0 1.3e-172 574.3 0.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF3172 PF11371.3 KND98308.1 - 0.064 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) Herpes_capsid PF06112.6 KND98308.1 - 3.7 7.5 9.5 6.9 6.6 6.6 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein HSP20 PF00011.16 KND98310.1 - 3.9e-05 23.4 9.4 0.035 13.9 0.2 3.8 4 0 0 4 4 4 2 Hsp20/alpha crystallin family DUF1675 PF07897.6 KND98310.1 - 5 6.8 14.4 12 5.7 10.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Corona_nucleoca PF00937.13 KND98310.1 - 7.1 5.4 10.9 14 4.5 7.6 1.4 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein AA_permease PF00324.16 KND98311.1 - 6e-79 265.6 45.4 1.8e-78 263.9 31.5 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND98311.1 - 3e-28 98.5 37.8 8.1e-28 97.1 26.2 1.6 1 1 0 1 1 1 1 Amino acid permease Ded_cyto PF06920.8 KND98312.1 - 2.4e-22 79.1 0.0 8e-22 77.3 0.0 1.9 2 0 0 2 2 2 1 Dedicator of cytokinesis rve_3 PF13683.1 KND98312.1 - 0.086 12.3 0.0 15 5.1 0.0 2.8 2 0 0 2 2 2 0 Integrase core domain PP-binding PF00550.20 KND98313.1 - 4.2e-11 42.9 1.2 7.1e-11 42.2 0.8 1.4 1 1 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 KND98313.1 - 9e-06 25.6 1.3 1.8e-05 24.6 0.6 1.6 1 1 1 2 2 2 1 Acyl-carrier DUF1493 PF07377.7 KND98313.1 - 0.015 15.3 0.2 0.021 14.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Ribosomal_L50 PF10501.4 KND98313.1 - 0.12 12.3 0.1 0.22 11.5 0.1 1.5 1 1 0 1 1 1 0 Ribosomal subunit 39S LRR_4 PF12799.2 KND98314.1 - 2.1e-43 145.3 41.8 1.2e-10 40.7 1.3 7.3 4 2 2 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KND98314.1 - 1.2e-23 82.5 32.9 9.3e-07 28.5 1.5 5.7 4 2 2 6 6 6 5 Leucine rich repeat LRR_6 PF13516.1 KND98314.1 - 4.4e-12 44.7 29.5 0.19 11.9 0.0 11.1 10 1 1 11 11 11 4 Leucine Rich repeat LRR_7 PF13504.1 KND98314.1 - 1.9e-11 42.2 17.8 3.2 8.3 0.0 10.5 9 2 0 9 9 9 4 Leucine rich repeat LRR_1 PF00560.28 KND98314.1 - 1.8e-10 39.3 38.5 0.44 10.7 0.1 11.1 11 1 1 12 12 12 5 Leucine Rich Repeat LRR_9 PF14580.1 KND98314.1 - 4.3e-09 36.1 19.2 2.2e-05 24.0 3.4 3.4 1 1 2 3 3 3 3 Leucine-rich repeat LRR_3 PF07725.7 KND98314.1 - 0.0039 16.8 10.4 23 5.0 0.0 6.7 6 0 0 6 6 6 0 Leucine Rich Repeat DUF3744 PF12558.3 KND98314.1 - 3.4 8.1 14.3 2.3 8.7 0.8 4.4 3 2 1 4 4 4 0 ATP-binding cassette cobalt transporter HSP20 PF00011.16 KND98315.1 - 2.1e-05 24.2 2.3 2.9e-05 23.8 1.6 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family V_ATPase_I PF01496.14 KND98315.1 - 0.055 11.3 0.1 0.058 11.2 0.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RE_ScaI PF09569.5 KND98315.1 - 0.092 12.2 0.2 0.12 11.8 0.2 1.2 1 0 0 1 1 1 0 ScaI restriction endonuclease ACOX PF01756.14 KND98317.1 - 1.8e-48 164.4 0.0 3.6e-48 163.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 KND98317.1 - 7.4e-17 60.5 0.4 1.8e-16 59.3 0.3 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 KND98317.1 - 3.5e-14 53.1 0.0 8e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 KND98317.1 - 0.0008 19.5 0.2 0.023 14.7 0.1 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain IF-2B PF01008.12 KND98318.1 - 5.1e-63 212.6 0.3 1.9e-62 210.8 0.2 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family DrrA_P4M PF14860.1 KND98318.1 - 0.074 12.7 0.8 0.12 12.1 0.6 1.3 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain MCP_N PF05581.7 KND98318.1 - 0.096 12.8 0.6 0.28 11.3 0.4 1.8 1 0 0 1 1 1 0 Vibrio chemotaxis protein N terminus Med1 PF10744.4 KND98319.1 - 2.8e-37 128.4 6.2 4.2e-37 127.8 4.3 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Ubie_methyltran PF01209.13 KND98320.1 - 1.7e-87 292.4 0.0 2e-87 292.1 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KND98320.1 - 2.7e-11 43.2 0.0 1.3e-10 41.1 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND98320.1 - 2.6e-10 40.6 0.0 4.5e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND98320.1 - 2.5e-09 37.4 0.0 1e-08 35.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND98320.1 - 2.5e-07 30.9 0.0 4.5e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND98320.1 - 8.5e-07 28.8 0.0 1.4e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND98320.1 - 5.2e-05 23.7 0.0 0.00011 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND98320.1 - 0.00011 22.1 0.0 0.00031 20.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KND98320.1 - 0.046 13.3 0.0 1.1 8.8 0.0 2.5 3 0 0 3 3 3 0 Hypothetical methyltransferase PK PF00224.16 KND98321.1 - 1.4e-167 556.6 1.8 1.8e-167 556.2 1.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 KND98321.1 - 4.2e-33 113.3 0.1 1.2e-32 111.9 0.1 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 KND98321.1 - 0.00061 18.7 0.5 0.0013 17.7 0.1 1.6 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family DnaJ PF00226.26 KND98322.1 - 7.5e-09 35.1 0.1 1.3e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 KND98322.1 - 0.00018 21.2 0.9 0.00023 20.9 0.6 1.4 1 1 0 1 1 1 1 Pam16 TLV_coat PF00429.14 KND98322.1 - 0.079 11.3 0.1 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) AAA PF00004.24 KND98323.1 - 6.5e-57 191.3 0.0 4e-43 146.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KND98323.1 - 8.8e-07 29.7 0.0 0.0013 19.4 0.0 3.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KND98323.1 - 1.2e-05 24.4 0.0 0.0015 17.6 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KND98323.1 - 0.00011 22.2 1.6 0.027 14.4 0.0 4.3 4 1 1 5 5 5 1 AAA ATPase domain AAA_22 PF13401.1 KND98323.1 - 0.00012 22.2 0.0 0.0061 16.6 0.0 3.5 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KND98323.1 - 0.00013 21.3 0.4 0.003 16.9 0.1 2.7 2 1 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 KND98323.1 - 0.00025 20.0 0.0 0.00047 19.1 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_2 PF07724.9 KND98323.1 - 0.0005 20.0 0.0 0.005 16.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Vps4_C PF09336.5 KND98323.1 - 0.00088 19.1 0.1 0.018 14.8 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_14 PF13173.1 KND98323.1 - 0.001 18.9 0.1 0.075 12.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KND98323.1 - 0.0014 18.0 0.0 0.003 16.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 KND98323.1 - 0.0022 18.1 0.0 0.015 15.4 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.9 KND98323.1 - 0.0028 17.3 0.4 0.041 13.6 0.0 3.2 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) PhoH PF02562.11 KND98323.1 - 0.0065 15.7 0.1 0.09 11.9 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein KaiC PF06745.8 KND98323.1 - 0.0079 15.3 0.0 0.02 14.0 0.0 1.6 1 0 0 1 1 1 1 KaiC AAA_19 PF13245.1 KND98323.1 - 0.0085 15.8 0.0 0.029 14.0 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 KND98323.1 - 0.0093 14.7 0.0 0.021 13.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 KND98323.1 - 0.012 15.4 0.0 0.31 10.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KND98323.1 - 0.013 14.6 0.0 0.037 13.1 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 KND98323.1 - 0.013 15.0 0.1 0.81 9.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 KND98323.1 - 0.016 15.2 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KND98323.1 - 0.016 15.4 0.1 0.081 13.2 0.0 2.3 3 0 0 3 3 1 0 AAA domain AAA_3 PF07726.6 KND98323.1 - 0.028 14.0 0.0 1.1 8.8 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 KND98323.1 - 0.032 14.1 0.0 9.1 6.1 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase AAA_24 PF13479.1 KND98323.1 - 0.045 13.3 0.4 0.18 11.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KND98323.1 - 0.053 13.1 0.1 2.4 7.8 0.0 2.8 3 0 0 3 3 3 0 NACHT domain Ribosomal_L31e PF01198.14 KND98324.1 - 4.5e-16 58.2 0.1 5.5e-16 58.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e ING PF12998.2 KND98326.1 - 0.011 15.9 2.4 0.011 15.9 1.7 1.7 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DivIVA PF05103.8 KND98326.1 - 0.061 13.3 7.7 0.064 13.3 1.7 2.5 2 1 0 2 2 2 0 DivIVA protein Blo-t-5 PF11642.3 KND98326.1 - 0.065 12.9 1.6 0.11 12.2 1.1 1.4 1 0 0 1 1 1 0 Mite allergen Blo t 5 FH2 PF02181.18 KND98326.1 - 0.07 12.0 2.5 0.074 11.9 1.5 1.3 1 1 0 1 1 1 0 Formin Homology 2 Domain Vps51 PF08700.6 KND98326.1 - 0.13 12.1 5.8 1.2 9.0 3.8 2.4 1 1 0 1 1 1 0 Vps51/Vps67 Tektin PF03148.9 KND98326.1 - 0.17 10.3 7.9 0.07 11.6 2.0 1.9 1 1 1 2 2 2 0 Tektin family NUC130_3NT PF08158.7 KND98326.1 - 0.18 12.0 0.7 1.4 9.2 0.1 2.2 2 0 0 2 2 2 0 NUC130/3NT domain Tropomyosin_1 PF12718.2 KND98326.1 - 0.27 11.0 7.8 0.073 12.9 3.2 1.6 2 0 0 2 2 2 0 Tropomyosin like DUF724 PF05266.9 KND98326.1 - 0.68 9.5 5.1 0.19 11.2 1.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4600 PF15372.1 KND98326.1 - 2.1 8.6 7.7 1.1 9.4 3.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) Prefoldin_2 PF01920.15 KND98326.1 - 4.1 7.2 12.4 3.4 7.4 0.6 3.1 2 1 2 4 4 4 0 Prefoldin subunit DUF4050 PF13259.1 KND98327.1 - 3.3e-19 68.9 5.0 4.9e-19 68.4 3.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) Rxt3 PF08642.5 KND98328.1 - 2.2e-27 95.5 0.0 9e-27 93.6 0.0 2.1 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 EMP24_GP25L PF01105.19 KND98328.1 - 0.061 13.0 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Spore_YtfJ PF09579.5 KND98328.1 - 0.086 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) Vps39_1 PF10366.4 KND98329.1 - 1.7e-33 114.8 1.0 1.7e-33 114.8 0.7 2.9 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 KND98329.1 - 4.5e-18 65.4 0.0 1.4e-17 63.8 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Utp21 PF04192.7 KND98330.1 - 5e-76 254.9 0.1 6.9e-76 254.4 0.1 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 KND98330.1 - 2.5e-17 62.0 6.3 2.5e-09 36.6 0.1 8.0 9 0 0 9 9 9 4 WD domain, G-beta repeat PQQ_2 PF13360.1 KND98330.1 - 8.2e-07 28.7 0.0 0.0033 16.9 0.0 3.3 2 2 0 2 2 2 2 PQQ-like domain Nup160 PF11715.3 KND98330.1 - 0.0033 15.6 0.1 0.029 12.5 0.0 2.3 2 0 0 2 2 2 1 Nucleoporin Nup120/160 eIF2A PF08662.6 KND98330.1 - 0.0094 15.6 0.0 0.71 9.5 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 KND98330.1 - 0.019 14.4 0.0 0.072 12.6 0.0 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Dus PF01207.12 KND98331.1 - 8.9e-45 152.8 0.1 8e-43 146.4 0.0 2.8 2 1 0 2 2 2 1 Dihydrouridine synthase (Dus) PEP_mutase PF13714.1 KND98331.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase zf-CCCH PF00642.19 KND98331.1 - 0.44 10.3 2.0 1.2 8.9 0.4 2.2 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Bap31 PF05529.7 KND98332.1 - 8.3e-58 195.0 0.0 9.7e-58 194.7 0.0 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like TMF_DNA_bd PF12329.3 KND98332.1 - 0.046 13.5 1.5 0.092 12.5 1.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 KND98332.1 - 0.071 12.6 1.0 0.35 10.3 0.7 2.1 2 0 0 2 2 2 0 Septum formation initiator Mem_trans PF03547.13 KND98333.1 - 7.7e-55 185.7 0.1 1.6e-54 184.6 0.0 1.5 1 1 0 1 1 1 1 Membrane transport protein SSrecog PF03531.9 KND98335.1 - 2.3e-77 259.2 5.6 5.9e-77 257.9 3.0 2.3 2 1 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 KND98335.1 - 1.7e-28 98.4 0.0 7.7e-26 89.9 0.0 3.4 4 0 0 4 4 4 2 Histone chaperone Rttp106-like Vps39_1 PF10366.4 KND98336.1 - 0.079 12.9 0.0 0.088 12.8 0.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Semialdhyde_dhC PF02774.13 KND98337.1 - 4.7e-42 143.9 0.0 6.7e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 KND98337.1 - 1.4e-30 106.0 0.0 2.4e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 KND98337.1 - 0.0018 18.8 0.0 0.0044 17.5 0.0 1.7 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Saccharop_dh PF03435.13 KND98337.1 - 0.04 12.9 0.1 0.12 11.3 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase DapB_N PF01113.15 KND98337.1 - 0.076 12.9 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Methyltransf_16 PF10294.4 KND98338.1 - 2.1e-12 46.8 0.0 1.3e-05 24.7 0.0 2.1 1 1 1 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 KND98338.1 - 0.034 14.7 0.0 0.058 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SAC3_GANP PF03399.11 KND98339.1 - 3.7e-61 206.2 0.2 8.1e-61 205.1 0.2 1.6 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family SAC3 PF12209.3 KND98339.1 - 9.5e-16 57.7 0.2 3e-15 56.1 0.1 1.9 1 0 0 1 1 1 1 Leucine permease transcriptional regulator helical domain ENTH PF01417.15 KND98340.1 - 4.3e-45 152.5 0.1 6.2e-45 152.0 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KND98340.1 - 0.00066 18.4 0.0 0.00091 18.0 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 KND98340.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 VHS domain DUF3742 PF12553.3 KND98340.1 - 9.6 6.7 7.9 7.6 7.0 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3742) Pro_isomerase PF00160.16 KND98341.1 - 1e-46 158.9 0.1 1.2e-46 158.7 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-C2H2_6 PF13912.1 KND98343.1 - 0.001 18.8 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KND98343.1 - 0.0041 17.2 0.0 0.0074 16.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KND98343.1 - 0.0043 17.3 0.1 0.008 16.4 0.0 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.2 KND98343.1 - 0.0053 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF1777 PF08648.7 KND98343.1 - 0.0078 15.9 5.4 0.0078 15.9 3.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) Toxin_63 PF15541.1 KND98343.1 - 0.014 15.3 0.1 0.025 14.5 0.1 1.4 1 0 0 1 1 1 0 Putative toxin 63 zf-C2H2_2 PF12756.2 KND98343.1 - 0.017 15.2 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 KND98343.1 - 0.024 14.7 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding POP1 PF06978.6 KND98343.1 - 0.77 9.3 8.1 0.34 10.5 2.5 2.1 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 DUF1168 PF06658.7 KND98343.1 - 8.2 5.9 17.4 1.1 8.7 7.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) PNK3P PF08645.6 KND98344.1 - 4.7e-45 152.8 0.0 6.1e-45 152.5 0.0 1.1 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase HAD PF12710.2 KND98344.1 - 0.082 13.0 0.1 0.18 11.9 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase ADK PF00406.17 KND98345.1 - 0.0034 17.2 0.1 0.0052 16.6 0.1 1.4 1 1 0 1 1 1 1 Adenylate kinase NotI PF12183.3 KND98345.1 - 0.058 12.4 0.0 0.078 12.0 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease NotI Ribosomal_S8 PF00410.14 KND98346.1 - 1.9e-11 43.8 0.0 2.3e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 TMEM192 PF14802.1 KND98347.1 - 0.063 12.1 0.2 0.23 10.2 0.1 1.9 1 0 0 1 1 1 0 TMEM192 family KxDL PF10241.4 KND98348.1 - 0.043 13.7 0.3 0.12 12.3 0.1 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein Zip PF02535.17 KND98349.1 - 1.5e-58 198.3 1.0 1.7e-58 198.1 0.7 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter CBS PF00571.23 KND98350.1 - 1.3e-30 104.8 3.9 1.7e-12 46.8 0.1 4.5 4 1 0 4 4 4 4 CBS domain OPT PF03169.10 KND98351.1 - 2e-149 498.8 27.0 2.3e-149 498.7 18.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein KH_1 PF00013.24 KND98352.1 - 2.9e-35 119.6 1.1 3.5e-13 48.9 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KND98352.1 - 1.8e-24 84.8 6.1 6.9e-09 35.1 0.4 3.6 3 1 0 3 3 3 3 KH domain KH_2 PF07650.12 KND98352.1 - 1.5e-11 43.7 0.7 0.0015 18.0 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KND98352.1 - 2e-05 24.1 0.4 0.21 11.2 0.0 3.3 3 0 0 3 3 3 2 KH domain KLRAQ PF10205.4 KND98352.1 - 0.012 15.5 2.0 0.025 14.6 1.4 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein KH_5 PF13184.1 KND98352.1 - 0.24 11.2 4.9 9.1 6.1 0.1 3.2 3 0 0 3 3 3 0 NusA-like KH domain BCNT PF07572.7 KND98353.1 - 1.5e-24 85.6 3.6 3.8e-24 84.4 2.5 1.7 1 0 0 1 1 1 1 Bucentaur or craniofacial development DNA_repr_REX1B PF14966.1 KND98353.1 - 0.75 10.2 0.0 0.75 10.2 0.0 2.7 4 0 0 4 4 4 0 DNA repair REX1-B Peptidase_M49 PF03571.10 KND98354.1 - 2e-226 752.4 0.1 2.9e-226 751.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M49 MogR_DNAbind PF12181.3 KND98354.1 - 0.018 14.8 0.3 0.042 13.6 0.2 1.5 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) ABC_membrane PF00664.18 KND98355.1 - 5.3e-46 157.2 4.9 7.7e-46 156.7 3.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KND98355.1 - 1.7e-28 99.6 0.0 6.1e-28 97.8 0.0 2.0 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KND98355.1 - 1.5e-06 27.5 0.0 2.7e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA PF00004.24 KND98355.1 - 6.5e-05 23.1 0.2 0.0022 18.1 0.1 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.4 KND98355.1 - 6.7e-05 21.6 0.1 0.00012 20.8 0.0 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_16 PF13191.1 KND98355.1 - 8.7e-05 22.5 0.1 0.0006 19.8 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KND98355.1 - 0.00029 20.9 0.2 0.011 15.9 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KND98355.1 - 0.00044 19.7 0.0 0.011 15.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KND98355.1 - 0.012 16.3 0.1 0.045 14.5 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 KND98355.1 - 0.025 14.8 0.6 3.1 8.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KND98355.1 - 0.052 13.4 0.3 0.31 10.9 0.2 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 KND98355.1 - 2.7 7.7 12.9 2.1 8.1 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function DUF87 ATP-synt_Eps PF04627.8 KND98356.1 - 2.9e-20 71.5 0.6 3.4e-20 71.3 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain T2SF PF00482.18 KND98356.1 - 0.032 14.1 0.1 0.039 13.8 0.1 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F OmpA PF00691.15 KND98356.1 - 0.055 13.8 0.3 0.058 13.8 0.2 1.1 1 0 0 1 1 1 0 OmpA family DNA_pol_phi PF04931.8 KND98357.1 - 4.8e-64 216.4 55.5 7.9e-45 152.9 22.4 3.3 2 1 0 2 2 2 2 DNA polymerase phi PfkB PF00294.19 KND98358.1 - 6.6e-70 235.6 1.3 7.8e-70 235.3 0.9 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KND98358.1 - 0.005 16.0 0.0 0.017 14.3 0.0 1.8 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase TRAM_LAG1_CLN8 PF03798.11 KND98359.1 - 1.2e-36 126.2 23.4 1.8e-36 125.5 16.2 1.3 1 0 0 1 1 1 1 TLC domain Ras PF00071.17 KND98360.1 - 4.3e-65 218.0 0.5 5.1e-65 217.7 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KND98360.1 - 5.5e-21 75.2 0.0 8e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KND98360.1 - 1e-17 63.8 0.1 1.3e-17 63.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KND98360.1 - 2.9e-08 33.1 0.1 3.2e-08 33.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KND98360.1 - 1.3e-05 25.0 0.1 2.2e-05 24.3 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KND98360.1 - 2.2e-05 23.9 0.1 4.3e-05 23.0 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KND98360.1 - 0.00035 20.7 0.0 0.0013 18.8 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 KND98360.1 - 0.00095 19.3 0.1 0.0093 16.1 0.0 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 KND98360.1 - 0.0012 18.0 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 KND98360.1 - 0.0049 16.8 0.2 0.072 13.0 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KND98360.1 - 0.014 14.6 0.0 0.039 13.1 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 KND98360.1 - 0.019 14.4 0.2 0.32 10.4 0.1 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 KND98360.1 - 0.02 14.1 0.1 0.15 11.3 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.22 KND98360.1 - 0.032 14.5 0.0 0.045 14.0 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 KND98360.1 - 0.034 13.6 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pam16 PF03656.8 KND98360.1 - 0.048 13.4 0.9 0.3 10.9 0.2 2.2 2 0 0 2 2 2 0 Pam16 AAA_5 PF07728.9 KND98360.1 - 0.054 13.2 0.0 0.098 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Septin PF00735.13 KND98360.1 - 0.058 12.4 0.0 0.14 11.1 0.0 1.6 2 0 0 2 2 2 0 Septin CENP-M PF11111.3 KND98360.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) DUF3237 PF11578.3 KND98361.1 - 5.3e-15 55.0 0.0 6e-15 54.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Rpn3_C PF08375.6 KND98363.1 - 6.8e-25 87.2 0.8 2.4e-24 85.4 0.3 2.1 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 KND98363.1 - 4.2e-21 75.2 1.5 1.4e-20 73.5 0.6 2.3 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 KND98363.1 - 0.0017 18.1 0.9 0.0032 17.2 0.1 1.9 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 TPR_2 PF07719.12 KND98363.1 - 0.016 15.1 2.6 0.84 9.7 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Ste50p-SAM PF09235.5 KND98363.1 - 0.042 13.8 0.1 2.2 8.3 0.0 2.9 1 1 1 2 2 2 0 Ste50p, sterile alpha motif Med17 PF10156.4 KND98364.1 - 7.1e-116 387.2 12.2 8.7e-116 386.9 8.5 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex DUF750 PF04721.12 KND98364.1 - 0.02 14.8 0.2 0.079 12.9 0.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF750) Ilm1 PF10311.4 KND98365.1 - 2.1e-35 121.6 13.5 8e-35 119.7 9.4 1.7 1 1 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Ribophorin_II PF05817.9 KND98367.1 - 0.00088 17.6 3.2 0.0012 17.1 2.2 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF1469 PF07332.6 KND98367.1 - 4.7 6.9 7.8 7.4 6.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) Peptidase_S24 PF00717.18 KND98368.1 - 0.0017 17.9 0.0 0.0059 16.2 0.0 2.0 2 1 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.4 KND98368.1 - 0.022 14.2 0.0 0.1 12.1 0.0 2.1 1 1 0 1 1 1 0 Signal peptidase, peptidase S26 Med26 PF08711.6 KND98369.1 - 5.5e-12 44.9 2.3 8.6e-12 44.3 0.1 2.3 2 0 0 2 2 2 1 TFIIS helical bundle-like domain DED PF01335.16 KND98369.1 - 0.048 13.7 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 Death effector domain NPDC1 PF06809.6 KND98369.1 - 0.075 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) LSM14 PF12701.2 KND98370.1 - 2.8e-26 91.1 0.0 5.2e-26 90.2 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 KND98370.1 - 7.5e-09 36.0 14.9 5.6e-06 26.8 0.7 3.0 3 1 1 4 4 4 2 FDF domain SM-ATX PF14438.1 KND98370.1 - 0.002 18.0 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain API5 PF05918.6 KND98370.1 - 0.16 10.4 7.6 0.22 10.0 5.3 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) FoP_duplication PF13865.1 KND98370.1 - 5.2 7.5 9.6 13 6.2 6.6 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Ribosom_S12_S23 PF00164.20 KND98371.1 - 1.9e-40 137.0 0.3 2.3e-40 136.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Mito_carr PF00153.22 KND98372.1 - 6.4e-54 179.6 0.0 7.7e-20 70.4 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF1761 PF08570.5 KND98372.1 - 0.009 16.0 0.0 0.042 13.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1761) Aldo_ket_red PF00248.16 KND98373.1 - 5.2e-57 192.8 0.1 7.2e-57 192.3 0.1 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Spore_III_AB PF09548.5 KND98373.1 - 0.079 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Hexapep_2 PF14602.1 KND98374.1 - 4e-10 39.0 4.6 1.4e-09 37.3 2.9 2.0 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 KND98374.1 - 1.6e-09 36.8 10.7 6.2e-09 34.9 4.2 2.6 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 KND98374.1 - 2.9e-09 36.7 1.4 5.4e-09 35.9 0.9 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Yip1 PF04893.12 KND98375.1 - 2e-12 46.9 16.6 3.4e-12 46.2 11.5 1.3 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 KND98375.1 - 1.1 8.8 16.4 2.5 7.7 11.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) Asp PF00026.18 KND98376.1 - 5.2e-41 140.9 4.0 7.2e-41 140.4 2.8 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KND98376.1 - 5.6e-05 23.1 0.2 5.6e-05 23.1 0.2 2.1 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KND98376.1 - 0.0006 20.2 0.2 0.39 11.2 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KND98376.1 - 0.015 14.8 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Anp1 PF03452.9 KND98378.1 - 2.8e-112 374.3 0.0 3.3e-112 374.0 0.0 1.1 1 0 0 1 1 1 1 Anp1 PGM_PMM_I PF02878.11 KND98380.1 - 3.8e-36 123.6 1.0 2.4e-35 121.0 0.7 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KND98380.1 - 2.7e-20 72.6 0.0 6e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 KND98380.1 - 4.1e-14 52.5 0.0 7.4e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 KND98380.1 - 3.2e-06 27.0 0.1 1.2e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Prp19 PF08606.6 KND98381.1 - 1.1e-31 108.3 3.7 8.1e-31 105.5 1.4 2.4 2 0 0 2 2 2 1 Prp19/Pso4-like U-box PF04564.10 KND98381.1 - 0.0061 16.4 0.1 0.017 15.0 0.0 1.8 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.3 KND98381.1 - 0.096 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF123 PF01986.11 KND98382.1 - 0.092 12.8 0.2 0.11 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF123 SUR7 PF06687.7 KND98383.1 - 6.6e-56 189.2 7.4 8.3e-56 188.8 5.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KND98383.1 - 0.00064 19.4 6.8 0.00064 19.4 4.7 1.8 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Sulfate_transp PF00916.15 KND98383.1 - 0.0044 16.0 2.7 0.53 9.2 0.3 2.3 2 0 0 2 2 2 2 Sulfate transporter family PMP22_Claudin PF00822.15 KND98383.1 - 0.0064 16.1 3.9 0.014 15.0 2.7 1.6 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Ndc1_Nup PF09531.5 KND98383.1 - 0.014 13.8 3.5 0.02 13.3 2.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2198 PF09964.4 KND98383.1 - 0.22 11.2 2.2 0.37 10.5 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) SdpI PF13630.1 KND98383.1 - 3.2 7.5 6.9 0.85 9.3 0.9 2.6 2 0 0 2 2 2 0 SdpI/YhfL protein family Tetraspannin PF00335.15 KND98383.1 - 5.2 6.2 24.8 6.6 5.9 8.2 3.1 2 1 1 3 3 3 0 Tetraspanin family NIF PF03031.13 KND98385.1 - 8.6e-26 90.4 0.0 3e-25 88.7 0.0 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.21 KND98385.1 - 1.8e-06 28.0 0.0 4.2e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KND98385.1 - 3.7e-05 23.4 0.0 0.00017 21.3 0.0 2.3 2 0 0 2 2 2 1 twin BRCT domain TAF8_C PF10406.4 KND98387.1 - 1.6e-19 69.6 1.0 5.8e-19 67.8 0.7 2.1 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Gamma-thionin PF00304.15 KND98388.1 - 0.026 14.5 0.5 0.032 14.2 0.4 1.1 1 0 0 1 1 1 0 Gamma-thionin family zf-C3HC PF07967.8 KND98388.1 - 0.039 13.7 0.1 0.042 13.6 0.1 1.1 1 0 0 1 1 1 0 C3HC zinc finger-like ubiquitin PF00240.18 KND98389.1 - 2.1e-17 62.2 0.2 3.4e-17 61.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KND98389.1 - 2.7e-12 46.2 0.1 4.4e-12 45.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 KND98389.1 - 1.4e-09 37.4 0.3 3.1e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain DUF2407 PF10302.4 KND98389.1 - 0.00079 19.5 0.0 0.0013 18.9 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 KND98389.1 - 0.0033 17.6 0.1 0.0072 16.5 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 KND98389.1 - 0.016 15.0 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF4293 PF14126.1 KND98390.1 - 0.024 14.5 1.0 0.03 14.2 0.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) GATA PF00320.22 KND98391.1 - 1.3e-08 34.0 6.4 1.3e-08 34.0 4.4 1.7 2 0 0 2 2 2 1 GATA zinc finger DZR PF12773.2 KND98391.1 - 4 7.3 7.5 6.2 6.7 3.7 2.3 2 1 0 2 2 2 0 Double zinc ribbon Bacteriocin_IIc PF10439.4 KND98394.1 - 6.4 6.9 13.9 3.6 7.7 7.5 1.9 1 1 1 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Metallophos PF00149.23 KND98396.1 - 1.2e-06 28.1 12.4 3.9e-06 26.4 8.6 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_S4e PF00900.15 KND98397.1 - 1.3e-30 104.8 1.3 2.8e-30 103.8 0.2 1.9 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 KND98397.1 - 1.4e-19 69.6 3.6 3e-19 68.5 2.5 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 KND98397.1 - 4.2e-07 29.2 0.0 7.6e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 KND98397.1 - 5e-05 22.8 4.0 5e-05 22.8 2.8 3.0 3 0 0 3 3 3 1 KOW motif RabGAP-TBC PF00566.13 KND98399.1 - 2.1e-45 154.8 3.3 2.1e-45 154.8 2.3 2.3 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Reo_sigmaC PF04582.7 KND98399.1 - 0.17 11.0 0.4 0.28 10.3 0.3 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein bZIP_1 PF00170.16 KND98399.1 - 0.25 11.3 18.2 0.86 9.6 0.9 4.3 4 0 0 4 4 4 0 bZIP transcription factor bZIP_2 PF07716.10 KND98399.1 - 8.6 6.2 19.1 5.7 6.8 0.7 4.0 3 1 0 3 3 3 0 Basic region leucine zipper Gal4_dimer PF03902.8 KND98402.1 - 1.4e-08 34.5 0.1 2.3e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 Gal4-like dimerisation domain Zn_clus PF00172.13 KND98402.1 - 4e-08 33.0 18.2 7.4e-08 32.1 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_3 PF08447.6 KND98405.1 - 0.0017 18.4 0.0 0.002 18.1 0.0 1.1 1 0 0 1 1 1 1 PAS fold DUF2951 PF11166.3 KND98405.1 - 0.066 13.0 0.7 0.072 12.9 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) RQC PF09382.5 KND98406.1 - 1.8e-23 82.2 0.1 5.3e-23 80.7 0.1 1.9 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.26 KND98406.1 - 1.8e-22 79.0 0.2 2.5e-19 68.9 0.0 3.3 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.24 KND98406.1 - 2e-21 76.2 0.0 4.4e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_Sgs1 PF11408.3 KND98406.1 - 1.1e-07 31.6 0.6 3.2e-07 30.0 0.4 1.8 1 0 0 1 1 1 1 Sgs1 RecQ helicase HRDC PF00570.18 KND98406.1 - 3.3e-07 29.9 0.3 2.1e-06 27.3 0.2 2.5 2 0 0 2 2 2 1 HRDC domain zf-CCCH PF00642.19 KND98410.1 - 2.2e-20 71.8 14.1 1.7e-12 46.7 0.6 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KND98410.1 - 0.0016 18.3 11.4 0.012 15.6 0.1 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type zf-CCHH PF10283.4 KND98410.1 - 6.8 6.6 11.6 8 6.3 0.9 3.3 3 0 0 3 3 3 0 Zinc-finger (CX5CX6HX5H) motif zf-HIT PF04438.11 KND98411.1 - 0.0025 17.4 17.3 0.004 16.7 12.0 1.4 1 0 0 1 1 1 1 HIT zinc finger DUF3554 PF12074.3 KND98412.1 - 5.8e-54 183.7 2.9 5.8e-54 183.7 2.0 5.6 6 0 0 6 6 6 3 Domain of unknown function (DUF3554) HEAT_2 PF13646.1 KND98412.1 - 3.1e-34 117.1 37.3 1.9e-06 28.0 0.0 15.1 10 4 6 16 16 16 10 HEAT repeats HEAT_EZ PF13513.1 KND98412.1 - 1.3e-32 111.4 35.1 0.0011 19.4 0.0 18.8 18 5 5 24 24 24 8 HEAT-like repeat HEAT PF02985.17 KND98412.1 - 5.7e-31 103.7 26.4 0.014 15.4 0.0 20.4 23 0 0 23 23 23 5 HEAT repeat CLASP_N PF12348.3 KND98412.1 - 5e-25 88.1 3.4 2.8e-09 36.6 0.0 8.5 8 1 2 10 10 10 3 CLASP N terminal Vac14_Fab1_bd PF12755.2 KND98412.1 - 6.3e-17 61.7 0.1 0.079 13.3 0.0 11.3 10 2 1 12 12 12 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KND98412.1 - 5.4e-15 55.6 7.7 7.2e-06 25.9 0.0 9.9 11 2 2 13 13 13 3 non-SMC mitotic condensation complex subunit 1 ALF PF03752.8 KND98412.1 - 0.0072 16.1 1.6 1.8 8.5 0.0 4.0 4 0 0 4 4 4 1 Short repeats of unknown function Cohesin_HEAT PF12765.2 KND98412.1 - 0.44 10.5 14.2 0.72 9.8 0.3 5.3 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion MDMPI_C PF07398.6 KND98413.1 - 0.45 11.1 6.1 0.19 12.3 2.2 1.8 1 1 0 2 2 2 0 MDMPI C-terminal domain NTPase_I-T PF01931.13 KND98418.1 - 0.12 12.1 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF84 Oxysterol_BP PF01237.13 KND98419.1 - 0.059 11.8 0.7 0.063 11.7 0.5 1.0 1 0 0 1 1 1 0 Oxysterol-binding protein RRM_1 PF00076.17 KND98420.1 - 4e-26 90.4 1.8 1.6e-12 46.8 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND98420.1 - 2.4e-23 81.8 1.0 3e-11 43.1 0.1 3.2 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND98420.1 - 6.6e-18 64.3 0.4 5.7e-06 26.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KND98420.1 - 0.00043 20.0 0.0 1.4 8.7 0.0 2.7 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif JAB PF01398.16 KND98421.1 - 3.1e-29 101.0 0.1 7.7e-29 99.7 0.1 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KND98421.1 - 5.4e-07 29.1 0.0 1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Daxx PF03344.10 KND98421.1 - 1.2 7.5 23.2 1.7 7.0 16.1 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 KND98421.1 - 1.6 6.5 23.7 2.2 6.0 16.4 1.2 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.6 KND98421.1 - 1.8 6.3 9.6 2.7 5.7 6.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.7 KND98421.1 - 2.9 7.0 19.6 4.9 6.3 13.6 1.4 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 KND98421.1 - 4.1 5.3 17.3 6.3 4.7 12.0 1.3 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 KND98421.1 - 7.6 6.0 20.1 15 5.0 13.9 1.5 1 0 0 1 1 1 0 YL1 nuclear protein UCH PF00443.24 KND98422.1 - 5.4e-54 183.0 1.9 5.4e-54 183.0 1.3 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KND98422.1 - 2e-13 50.4 2.5 1.2e-12 47.8 1.7 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 KND98422.1 - 0.016 14.5 0.4 0.095 11.9 0.2 2.3 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Yippee-Mis18 PF03226.9 KND98423.1 - 5.3e-14 52.0 0.5 8e-14 51.4 0.3 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Eapp_C PF10238.4 KND98423.1 - 0.017 15.0 0.5 0.55 10.1 0.0 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein Rsm1 PF08600.5 KND98423.1 - 0.041 13.7 0.1 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Rsm1-like Baculo_LEF-2 PF03041.9 KND98423.1 - 0.21 11.2 2.2 0.22 11.2 0.0 1.8 1 1 0 2 2 2 0 lef-2 Ribosomal_L22 PF00237.14 KND98428.1 - 3.3e-19 68.7 0.1 4.9e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Fer2_2 PF01799.15 KND98428.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 [2Fe-2S] binding domain SHR3_chaperone PF08229.6 KND98430.1 - 6.7e-76 253.6 0.2 8.5e-76 253.2 0.1 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 Nitroreductase PF00881.19 KND98430.1 - 0.11 12.3 0.4 16 5.2 0.0 2.6 1 1 1 2 2 2 0 Nitroreductase family Ras PF00071.17 KND98431.1 - 1.2e-56 190.5 0.0 1.5e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KND98431.1 - 1.1e-14 54.9 0.0 1.8e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KND98431.1 - 1.4e-08 34.2 0.0 1.8e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KND98431.1 - 0.055 12.8 0.0 0.15 11.4 0.0 1.6 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 KND98431.1 - 0.093 12.2 0.7 0.3 10.6 0.2 1.9 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.17 KND98433.1 - 1.1e-08 34.5 0.0 2.7e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND98433.1 - 3.4e-08 33.3 0.1 6.2e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.7 KND98433.1 - 0.24 9.2 27.1 0.12 10.2 7.5 2.1 2 0 0 2 2 2 0 Nop14-like family WD40 PF00400.27 KND98434.1 - 1.2e-15 56.6 2.4 2.4e-05 24.0 0.2 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF2213 PF09979.4 KND98434.1 - 0.038 13.6 0.7 0.087 12.4 0.5 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2213) Fib_alpha PF08702.5 KND98434.1 - 0.089 12.9 4.7 0.14 12.2 3.3 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2509 PF10713.4 KND98434.1 - 0.09 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2509) DUF4446 PF14584.1 KND98434.1 - 1.9 8.2 4.6 3 7.6 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) adh_short PF00106.20 KND98435.1 - 4.2e-12 46.3 0.0 6.5e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND98435.1 - 4.5e-10 39.4 0.0 6.8e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Pkinase PF00069.20 KND98436.1 - 2.3e-62 210.5 0.0 3.2e-62 210.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND98436.1 - 8.1e-25 87.3 0.0 1.3e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KND98436.1 - 0.02 14.6 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L11_N PF03946.9 KND98437.1 - 1.3e-24 85.4 0.4 2.2e-24 84.6 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KND98437.1 - 6.2e-22 77.5 0.0 1e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain P12 PF12669.2 KND98438.1 - 0.096 12.8 2.7 0.26 11.5 1.9 1.7 1 1 0 1 1 1 0 Virus attachment protein p12 family Mid2 PF04478.7 KND98440.1 - 0.015 14.7 0.2 0.026 13.9 0.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor SR-25 PF10500.4 KND98441.1 - 0.035 13.5 1.0 0.051 13.0 0.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein WD40 PF00400.27 KND98445.1 - 1.3e-13 50.2 11.7 3.1e-05 23.6 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat GDC-P PF02347.11 KND98448.1 - 7.4e-190 631.1 0.0 9.3e-177 588.0 0.0 2.4 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.14 KND98448.1 - 0.00013 20.8 0.1 0.0064 15.2 0.0 2.4 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 KND98448.1 - 0.0033 16.6 0.1 0.0078 15.3 0.0 1.6 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_3 PF00202.16 KND98448.1 - 0.0092 14.8 0.0 0.029 13.2 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-III DUF1910 PF08928.5 KND98451.1 - 0.038 14.0 0.1 0.055 13.4 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) 7tm_1 PF00001.16 KND98452.1 - 0.065 12.3 0.2 0.092 11.8 0.1 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Peptidase_M3 PF01432.15 KND98453.1 - 2.3e-104 349.9 0.0 3.6e-104 349.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 DUF3574 PF12098.3 KND98453.1 - 0.081 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) AA_permease PF00324.16 KND98455.1 - 3.9e-141 470.6 35.5 4.4e-141 470.4 24.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND98455.1 - 2.8e-41 141.4 38.3 3.7e-41 141.0 26.5 1.1 1 0 0 1 1 1 1 Amino acid permease Arrestin_N PF00339.24 KND98456.1 - 0.031 14.0 0.3 0.13 12.0 0.0 2.1 3 1 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain Arrestin_N PF00339.24 KND98457.1 - 0.017 14.9 0.0 0.038 13.8 0.0 1.7 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain GRAS PF03514.9 KND98457.1 - 0.057 12.1 0.0 0.083 11.6 0.0 1.2 1 0 0 1 1 1 0 GRAS domain family AF-4 PF05110.8 KND98459.1 - 1.3 6.8 11.5 1.4 6.7 8.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DNA_pol_viral_N PF00242.12 KND98459.1 - 4.4 6.2 7.4 4.6 6.1 5.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Period_C PF12114.3 KND98459.1 - 9.8 5.7 12.3 16 5.0 8.5 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region SR-25 PF10500.4 KND98461.1 - 1.7 8.0 11.8 2.1 7.7 8.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAM70 PF14967.1 KND98461.1 - 3.3 6.8 7.3 3.8 6.6 5.1 1.1 1 0 0 1 1 1 0 FAM70 protein DUF2749 PF10907.3 KND98462.1 - 0.012 15.4 4.6 1.2 9.0 3.2 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2749) DUF3859 PF12975.2 KND98463.1 - 0.12 12.0 0.9 0.4 10.3 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3859) SR-25 PF10500.4 KND98463.1 - 9.1 5.6 10.4 13 5.1 7.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4376 PF14301.1 KND98468.1 - 0.044 13.9 0.5 0.044 13.9 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) CARDB PF07705.6 KND98468.1 - 9.7 6.3 8.5 4.1 7.5 0.1 2.9 1 1 1 2 2 2 0 CARDB Arrestin_N PF00339.24 KND98471.1 - 2.5e-11 43.5 0.3 2e-09 37.4 0.0 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KND98471.1 - 0.0063 16.6 0.4 2.9 7.9 0.1 3.0 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.10 KND98471.1 - 0.0084 14.9 0.1 0.023 13.4 0.0 1.7 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 26 RTA1 PF04479.8 KND98472.1 - 4.7e-61 206.1 13.4 4.7e-61 206.1 9.3 1.6 2 0 0 2 2 2 1 RTA1 like protein DUF373 PF04123.8 KND98472.1 - 0.35 9.8 11.2 0.11 11.5 5.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF373) FixH PF05751.6 KND98472.1 - 1.1 9.0 3.1 12 5.6 0.0 3.1 3 0 0 3 3 3 0 FixH Rer1 PF03248.8 KND98472.1 - 1.7 8.2 5.6 0.38 10.3 1.0 2.0 2 0 0 2 2 2 0 Rer1 family Abhydrolase_9_N PF15420.1 KND98472.1 - 4.2 7.0 8.1 1.7 8.3 0.9 2.6 1 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus 2TM PF13239.1 KND98474.1 - 0.04 13.9 1.1 0.04 13.9 0.7 1.1 1 0 0 1 1 1 0 2TM domain RTA1 PF04479.8 KND98475.1 - 2.1e-56 190.9 12.7 3.7e-56 190.1 8.8 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF63 PF01889.12 KND98475.1 - 0.0094 16.0 2.6 0.0094 16.0 1.8 2.1 2 1 0 2 2 2 1 Membrane protein of unknown function DUF63 Abhydrolase_9_N PF15420.1 KND98475.1 - 0.095 12.4 12.8 0.06 13.0 7.1 1.9 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Chordopox_L2 PF05803.7 KND98475.1 - 9.2 5.9 11.2 2.7 7.6 0.5 3.2 3 0 0 3 3 3 0 Chordopoxvirus L2 protein CRAL_TRIO PF00650.15 KND98478.1 - 6.4e-37 126.4 0.0 1.8e-36 125.0 0.0 1.7 1 1 1 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KND98478.1 - 1.9e-08 34.3 0.0 3.7e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KND98478.1 - 4.7e-07 29.8 0.2 1.6e-06 28.1 0.1 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain UPF0731 PF14982.1 KND98479.1 - 0.029 14.2 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 UPF0731 family EST1 PF10374.4 KND98480.1 - 0.1 12.5 0.2 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Telomerase activating protein Est1 KH_1 PF00013.24 KND98484.1 - 3.8e-22 77.6 2.9 1.7e-06 27.5 0.0 7.7 8 1 0 8 8 8 5 KH domain KH_3 PF13014.1 KND98484.1 - 2.2e-11 43.1 1.4 0.016 14.8 0.0 5.6 5 0 0 5 5 5 3 KH domain SLS PF14611.1 KND98484.1 - 0.18 11.1 3.8 16 4.8 0.0 3.8 4 0 0 4 4 4 0 Mitochondrial inner-membrane-bound regulator p450 PF00067.17 KND98485.1 - 2.2e-54 184.7 0.0 2.6e-54 184.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 HnRNP_M PF11532.3 KND98486.1 - 0.062 13.4 0.6 0.11 12.6 0.4 1.4 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein M Phage_holin_2 PF04550.7 KND98487.1 - 0.022 14.8 0.1 0.13 12.3 0.1 2.0 2 0 0 2 2 2 0 Phage holin family 2 DUF1195 PF06708.6 KND98488.1 - 0.14 11.5 1.0 6.9 6.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1195) CFEM PF05730.6 KND98490.1 - 0.0012 18.5 1.3 0.0035 17.1 0.9 1.8 1 0 0 1 1 1 1 CFEM domain Sporozoite_P67 PF05642.6 KND98490.1 - 0.0053 14.6 8.7 0.0059 14.5 6.0 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Mucin PF01456.12 KND98490.1 - 0.024 14.4 20.4 0.027 14.2 14.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein MSA-2c PF12238.3 KND98490.1 - 0.09 12.4 9.6 0.14 11.7 6.7 1.4 1 1 0 1 1 1 0 Merozoite surface antigen 2c Mnd1 PF03962.10 KND98490.1 - 0.12 12.0 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 Mnd1 family Plasmodium_Vir PF05795.6 KND98490.1 - 0.15 11.2 3.1 0.17 11.0 2.1 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TFIIA PF03153.8 KND98490.1 - 0.2 11.5 7.8 0.21 11.4 5.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 KND98490.1 - 0.44 8.7 8.0 0.43 8.8 5.6 1.0 1 0 0 1 1 1 0 Transmembrane protein Mitofilin PF09731.4 KND98490.1 - 0.75 8.3 7.9 0.77 8.3 5.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CDC27 PF09507.5 KND98490.1 - 1.8 7.6 13.8 2.1 7.5 9.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SOG2 PF10428.4 KND98490.1 - 1.8 7.0 9.7 1.9 7.0 6.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Herpes_BLLF1 PF05109.8 KND98490.1 - 1.9 6.3 19.2 2.1 6.1 13.3 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DHHW PF14286.1 KND98490.1 - 5.6 6.1 6.6 7.1 5.8 4.6 1.1 1 0 0 1 1 1 0 DHHW protein Trs65 PF12735.2 KND98490.1 - 9.5 5.4 7.5 12 5.0 5.2 1.1 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 CFEM PF05730.6 KND98494.1 - 4.9e-13 48.6 5.3 8.2e-13 47.9 3.6 1.4 1 0 0 1 1 1 1 CFEM domain Golgin_A5 PF09787.4 KND98494.1 - 0.44 9.0 2.2 0.57 8.6 1.5 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Ferric_reduct PF01794.14 KND98499.1 - 8.4e-17 61.4 10.1 8.4e-17 61.4 7.0 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KND98499.1 - 2.3e-14 53.1 0.5 6.6e-14 51.6 0.3 1.8 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KND98499.1 - 4.2e-10 39.7 0.0 7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.1 KND98499.1 - 1.2 9.3 14.1 3.3 7.9 0.6 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4405) Aldo_ket_red PF00248.16 KND98500.1 - 5.7e-40 136.9 0.0 7.1e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family GntR PF00392.16 KND98500.1 - 0.0035 16.7 0.0 0.27 10.7 0.0 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Glycos_trans_3N PF02885.12 KND98500.1 - 0.067 12.7 1.3 13 5.5 0.1 2.8 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain G_glu_transpept PF01019.16 KND98502.1 - 1.1e-131 439.8 0.0 1.2e-131 439.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase FmrO PF07091.6 KND98504.1 - 0.094 11.6 0.0 0.2 10.5 0.0 1.4 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) Rho_GDI PF02115.12 KND98507.1 - 1.9e-50 171.0 0.2 2.1e-50 170.9 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor UvrD_C PF13361.1 KND98508.1 - 2.1e-66 224.7 0.0 6.3e-66 223.2 0.0 1.8 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 KND98508.1 - 2.8e-63 214.1 2.9 4.9e-63 213.3 2.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.1 KND98508.1 - 8.5e-13 47.8 0.3 8e-12 44.7 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain UvrD_C_2 PF13538.1 KND98508.1 - 1.1e-12 48.0 0.0 4.7e-12 45.9 0.0 2.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.1 KND98508.1 - 2.4e-06 27.3 0.0 4.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 KND98508.1 - 2.2e-05 23.9 0.0 0.018 14.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KND98508.1 - 0.00026 20.6 0.3 0.00081 19.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain Treslin_N PF15292.1 KND98508.1 - 0.0013 16.6 0.1 0.0021 16.0 0.0 1.1 1 0 0 1 1 1 1 Treslin N-terminus Viral_helicase1 PF01443.13 KND98508.1 - 0.0024 17.4 0.1 16 4.9 0.0 3.6 3 1 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 KND98508.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 Helicase DEAD PF00270.24 KND98508.1 - 0.011 15.1 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF3410 PF11890.3 KND98508.1 - 0.067 12.8 0.5 0.91 9.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) Lectin_C PF00059.16 KND98509.1 - 0.018 15.7 2.2 0.023 15.3 0.5 2.1 2 0 0 2 2 2 0 Lectin C-type domain GCIP PF13324.1 KND98509.1 - 0.21 10.7 1.3 0.37 9.9 0.9 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Band_7 PF01145.20 KND98510.1 - 2.3e-24 86.2 1.3 3.5e-24 85.6 0.9 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family E_Pc_C PF06752.7 KND98510.1 - 0.00065 19.2 0.0 0.00088 18.8 0.0 1.2 1 0 0 1 1 1 1 Enhancer of Polycomb C-terminus Imm3 PF14425.1 KND98510.1 - 0.026 14.5 0.2 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 Immunity protein Imm3 SH3_9 PF14604.1 KND98511.1 - 3e-11 42.7 0.3 5.9e-11 41.7 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KND98511.1 - 3.1e-09 36.0 0.1 5.9e-09 35.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KND98511.1 - 8.4e-09 34.7 0.0 1.4e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain PAT1 PF09770.4 KND98511.1 - 0.48 8.6 6.2 0.47 8.6 4.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ALS_ss_C PF10369.4 KND98514.1 - 3e-19 68.5 0.0 9.3e-19 66.9 0.0 1.8 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 KND98514.1 - 2.2e-10 39.7 0.1 5.4e-10 38.5 0.1 1.7 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 KND98514.1 - 8.6e-05 22.2 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 ACT domain DUF1374 PF07118.6 KND98517.1 - 0.029 14.4 6.9 16 5.6 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1374) CBFD_NFYB_HMF PF00808.18 KND98519.1 - 9.1e-24 83.2 0.1 1.6e-23 82.5 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-18kDa PF02269.11 KND98519.1 - 0.0019 17.9 0.0 0.004 16.9 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 KND98519.1 - 0.0063 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 zf-Tim10_DDP PF02953.10 KND98519.1 - 0.038 13.2 0.1 0.077 12.2 0.0 1.5 1 0 0 1 1 1 0 Tim10/DDP family zinc finger TFIID_20kDa PF03847.8 KND98519.1 - 0.25 11.6 1.9 1.4 9.2 0.0 2.6 3 0 0 3 3 3 0 Transcription initiation factor TFIID subunit A SH3_1 PF00018.23 KND98520.1 - 3.5e-23 80.7 0.0 2.6e-12 45.9 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KND98520.1 - 4.7e-18 64.5 0.1 6.9e-11 41.5 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 KND98520.1 - 1.5e-11 44.0 0.9 2.6e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 PX domain SH3_2 PF07653.12 KND98520.1 - 2.8e-11 42.7 0.0 7.4e-09 34.9 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain Glypican PF01153.14 KND98523.1 - 0.26 9.8 7.1 0.43 9.1 4.9 1.2 1 0 0 1 1 1 0 Glypican Thioredoxin_4 PF13462.1 KND98524.1 - 1.3e-10 41.5 0.0 2.5e-10 40.5 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KND98524.1 - 0.02 15.1 0.0 0.098 12.8 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain BRF1 PF07741.8 KND98526.1 - 2.6 8.3 14.0 0.17 12.1 2.4 2.5 2 1 1 3 3 3 0 Brf1-like TBP-binding domain ABC2_membrane PF01061.19 KND98528.1 - 1.2e-74 250.0 51.2 7.4e-47 159.2 11.5 3.4 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 KND98528.1 - 7.4e-39 133.1 0.0 6.3e-19 68.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KND98528.1 - 1.3e-28 98.7 15.9 6.2e-27 93.2 0.0 3.5 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KND98528.1 - 6.4e-14 51.7 0.0 2.1e-13 50.1 0.0 1.8 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 KND98528.1 - 6e-11 41.9 10.2 6e-11 41.9 7.1 3.4 2 1 1 3 3 3 1 ABC-2 family transporter protein DUF258 PF03193.11 KND98528.1 - 2.3e-05 23.6 0.0 0.00016 20.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KND98528.1 - 0.00011 21.7 0.1 0.0013 18.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KND98528.1 - 0.00014 21.3 0.4 0.0038 16.7 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KND98528.1 - 0.00019 21.7 0.0 0.0052 17.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KND98528.1 - 0.00046 20.2 1.4 0.00077 19.4 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KND98528.1 - 0.00049 20.9 0.0 0.0066 17.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KND98528.1 - 0.0008 19.4 0.1 0.18 11.7 0.1 3.2 3 1 0 4 4 3 1 AAA domain SMC_N PF02463.14 KND98528.1 - 0.001 18.3 0.0 0.57 9.3 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.14 KND98528.1 - 0.0022 17.4 1.4 0.0029 17.0 0.0 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KND98528.1 - 0.0036 17.4 1.2 0.017 15.2 0.0 2.8 3 1 0 3 3 2 1 AAA domain AAA_23 PF13476.1 KND98528.1 - 0.0059 16.9 0.2 0.039 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KND98528.1 - 0.0065 16.3 0.2 0.035 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KND98528.1 - 0.015 14.8 1.9 0.055 13.1 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 KND98528.1 - 0.019 14.4 0.9 0.65 9.4 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CHD5 PF04420.9 KND98528.1 - 0.02 14.5 2.3 0.13 11.9 0.1 2.6 2 0 0 2 2 2 0 CHD5-like protein MMR_HSR1 PF01926.18 KND98528.1 - 0.021 14.7 0.0 0.25 11.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_ATPase PF09818.4 KND98528.1 - 0.047 12.2 0.0 0.087 11.3 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_28 PF13521.1 KND98528.1 - 0.048 13.6 0.6 0.17 11.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KND98528.1 - 0.082 12.8 0.0 2.8 7.9 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 KND98528.1 - 0.094 12.3 0.1 0.28 10.8 0.1 1.8 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 KND98528.1 - 0.1 12.3 1.4 1.4 8.6 0.0 3.0 3 0 0 3 3 3 0 Part of AAA domain AAA PF00004.24 KND98528.1 - 0.19 11.9 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 KND98528.1 - 0.21 10.6 0.0 0.43 9.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF3353 PF11833.3 KND98528.1 - 3.7 6.9 6.4 7.7 5.9 3.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) Hyphal_reg_CWP PF11765.3 KND98529.1 - 2.6e-33 115.2 5.1 2.6e-33 115.2 3.5 1.9 2 0 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal NMT1 PF09084.6 KND98530.1 - 1.9e-77 259.6 0.0 2.4e-77 259.3 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 KND98530.1 - 3.5e-07 29.8 0.0 0.047 13.0 0.0 3.2 2 1 2 4 4 4 2 NMT1-like family PBP_like PF12727.2 KND98530.1 - 0.081 11.8 0.0 0.21 10.4 0.0 1.6 1 1 1 2 2 2 0 PBP superfamily domain MFS_1 PF07690.11 KND98533.1 - 2e-30 105.7 25.3 2e-30 105.7 17.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KND98533.1 - 0.34 10.4 8.6 0.2 11.1 3.8 2.3 2 1 0 2 2 2 0 Ion channel regulatory protein UNC-93 Mannosyl_trans3 PF11051.3 KND98534.1 - 2e-55 188.0 0.0 2.5e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative DUF594 PF04578.8 KND98534.1 - 0.11 12.0 0.1 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF594 ABC_tran PF00005.22 KND98535.1 - 9.6e-08 32.4 0.8 4.2e-07 30.3 0.4 2.2 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KND98535.1 - 0.00034 20.6 0.0 0.00051 20.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KND98535.1 - 0.0018 18.4 0.1 0.006 16.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KND98535.1 - 0.0055 16.5 0.3 0.034 14.0 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.1 KND98535.1 - 0.013 15.8 3.4 0.02 15.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KND98535.1 - 0.018 14.7 0.1 0.042 13.5 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase DUF2664 PF10867.3 KND98535.1 - 0.048 14.2 2.1 0.15 12.7 1.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2664) AAA_25 PF13481.1 KND98535.1 - 0.053 12.9 0.5 0.13 11.6 0.1 1.8 1 1 1 2 2 2 0 AAA domain AAA_15 PF13175.1 KND98535.1 - 0.061 12.3 0.0 0.096 11.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.14 KND98535.1 - 0.063 12.5 0.0 0.11 11.7 0.0 1.7 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KND98535.1 - 0.064 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 KND98535.1 - 0.069 13.3 3.6 0.47 10.6 2.5 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KND98535.1 - 0.073 12.5 0.2 0.19 11.2 0.1 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TF_AP-2 PF03299.9 KND98535.1 - 0.085 12.4 3.0 0.29 10.6 1.0 2.1 1 1 1 2 2 2 0 Transcription factor AP-2 AAA_28 PF13521.1 KND98535.1 - 0.11 12.4 1.4 0.29 11.0 0.5 2.1 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 KND98535.1 - 0.17 12.7 0.6 0.41 11.4 0.3 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KND98535.1 - 0.62 10.0 7.1 53 3.7 4.9 2.4 1 1 0 1 1 1 0 AAA ATPase domain DUF4306 PF14154.1 KND98536.1 - 0.071 13.0 0.0 0.073 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) FAD_binding_7 PF03441.9 KND98537.1 - 1.7e-87 293.1 0.1 2.4e-87 292.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KND98537.1 - 1.7e-30 105.9 0.3 3.2e-30 105.0 0.2 1.4 1 0 0 1 1 1 1 DNA photolyase ANF_receptor PF01094.23 KND98537.1 - 0.071 11.8 0.0 0.14 10.8 0.0 1.5 1 0 0 1 1 1 0 Receptor family ligand binding region DUF1694 PF07997.6 KND98537.1 - 0.098 12.5 2.2 0.18 11.7 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1694) F-box-like PF12937.2 KND98538.1 - 0.00041 20.0 0.1 0.0015 18.2 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KND98538.1 - 0.0022 17.5 0.9 0.015 14.9 0.0 2.7 2 0 0 2 2 2 1 F-box domain AAA_31 PF13614.1 KND98538.1 - 0.017 15.0 3.5 0.14 12.0 0.0 3.0 4 0 0 4 4 4 0 AAA domain zf-H2C2_2 PF13465.1 KND98542.1 - 0.0006 19.9 4.5 0.022 15.0 0.2 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KND98542.1 - 0.0018 18.5 5.1 0.028 14.7 0.3 4.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KND98542.1 - 0.025 14.9 9.0 0.048 14.0 1.2 4.6 5 0 0 5 5 5 0 Zinc finger, C2H2 type RINT1_TIP1 PF04437.8 KND98542.1 - 0.028 12.9 0.5 0.038 12.5 0.4 1.1 1 0 0 1 1 1 0 RINT-1 / TIP-1 family zf-C2H2_jaz PF12171.3 KND98542.1 - 0.074 13.2 0.1 0.074 13.2 0.0 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Seipin PF06775.9 KND98545.1 - 0.014 14.9 0.9 0.53 9.7 0.1 2.2 2 0 0 2 2 2 0 Putative adipose-regulatory protein (Seipin) DUF1765 PF08578.5 KND98547.1 - 3e-34 117.7 9.5 1.9e-33 115.1 5.5 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) Choline_kinase PF01633.15 KND98548.1 - 1.8e-52 177.9 0.0 3.1e-52 177.2 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 KND98548.1 - 2.5e-12 46.0 1.1 1.5e-11 43.6 0.1 2.3 2 0 0 2 2 2 1 Choline kinase N terminus APH PF01636.18 KND98548.1 - 1.9e-07 31.0 0.3 7.3e-07 29.1 0.2 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF3885 PF13021.1 KND98548.1 - 0.2 11.4 1.9 1.1 9.0 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) WD40 PF00400.27 KND98549.1 - 1.6e-24 84.8 13.7 1.9e-06 27.5 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Adeno_shaft PF00608.12 KND98549.1 - 0.039 13.5 0.9 0.33 10.6 0.0 2.6 2 0 0 2 2 2 0 Adenoviral fibre protein (repeat/shaft region) UPF0728 PF15092.1 KND98550.1 - 0.098 12.5 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0728 KH_3 PF13014.1 KND98552.1 - 6.2e-14 51.2 0.1 3.8e-07 29.6 0.1 4.1 4 0 0 4 4 4 2 KH domain KH_1 PF00013.24 KND98552.1 - 5.9e-11 41.8 0.3 1.8e-08 33.8 0.1 3.9 4 0 0 4 4 4 1 KH domain Sugar_tr PF00083.19 KND98555.1 - 1.3e-97 327.1 19.5 1.6e-97 326.9 13.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND98555.1 - 2.3e-30 105.4 28.7 5.3e-30 104.3 14.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KND98555.1 - 0.082 12.7 5.3 0.07 12.9 0.3 3.0 3 0 0 3 3 3 0 MFS_1 like family Ribosomal_L7Ae PF01248.21 KND98558.1 - 8.7e-23 79.6 0.6 1.5e-22 78.8 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family UCR_hinge PF02320.11 KND98559.1 - 6.9e-25 86.7 9.4 1.1e-24 86.1 6.5 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Nop14 PF04147.7 KND98559.1 - 0.087 10.7 27.5 0.1 10.4 19.0 1.0 1 0 0 1 1 1 0 Nop14-like family Vanabin-2 PF11437.3 KND98559.1 - 0.1 12.5 2.4 0.17 11.8 1.6 1.3 1 0 0 1 1 1 0 Vanadium-binding protein 2 SpoIIIAH PF12685.2 KND98559.1 - 0.18 11.2 8.9 0.22 10.9 6.1 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein CDC45 PF02724.9 KND98559.1 - 0.37 8.7 17.6 0.43 8.5 12.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.10 KND98559.1 - 0.67 8.5 7.7 0.79 8.2 5.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRN3 PF05327.6 KND98559.1 - 1 7.3 14.7 1.5 6.8 10.2 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Daxx PF03344.10 KND98559.1 - 2.2 6.6 25.5 2.7 6.3 17.7 1.0 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 KND98559.1 - 4.1 6.3 25.9 5.2 6.0 18.0 1.1 1 0 0 1 1 1 0 BUD22 CENP-T PF15511.1 KND98559.1 - 6.4 5.9 17.3 7.4 5.7 12.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T RRM_1 PF00076.17 KND98561.1 - 6.9e-23 80.0 10.5 1.4e-13 50.2 0.6 4.2 4 1 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND98561.1 - 4.1e-19 68.3 2.5 7.2e-13 48.3 0.0 3.1 3 1 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND98561.1 - 8e-13 48.0 3.1 2e-06 27.5 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KND98561.1 - 0.036 13.8 0.1 0.036 13.8 0.1 2.4 2 1 1 3 3 3 0 Limkain b1 BRAP2 PF07576.7 KND98561.1 - 0.049 13.1 0.5 0.47 10.0 0.0 2.2 2 0 0 2 2 2 0 BRCA1-associated protein 2 Rtf2 PF04641.7 KND98561.1 - 0.18 10.9 12.4 0.29 10.2 8.6 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Cellulose_synt PF03552.9 KND98561.1 - 0.65 8.2 2.0 0.85 7.8 1.4 1.1 1 0 0 1 1 1 0 Cellulose synthase Ycf1 PF05758.7 KND98561.1 - 1.5 6.4 6.9 1.7 6.2 4.8 1.2 1 0 0 1 1 1 0 Ycf1 NARP1 PF12569.3 KND98561.1 - 2 7.0 15.1 2.9 6.5 10.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FancD2 PF14631.1 KND98561.1 - 3.9 4.4 7.2 5.1 4.0 5.0 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Vfa1 PF08432.5 KND98561.1 - 6.5 6.7 20.5 0.37 10.7 9.4 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Ribosomal_L2_C PF03947.13 KND98562.1 - 1.7e-39 134.5 3.4 2.6e-39 134.0 2.4 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KND98562.1 - 5.6e-14 51.8 0.1 1.3e-13 50.6 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SpoA PF01052.15 KND98562.1 - 0.1 12.2 0.1 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Surface presentation of antigens (SPOA) Bac_export_2 PF01312.14 KND98564.1 - 0.11 11.3 0.0 0.12 11.2 0.0 1.0 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family LHC PF00556.15 KND98564.1 - 7.7 6.4 6.2 1.5e+02 2.3 4.3 2.3 1 1 0 1 1 1 0 Antenna complex alpha/beta subunit ABC_tran PF00005.22 KND98565.1 - 9.4e-56 187.9 0.0 7.7e-33 113.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KND98565.1 - 5.9e-44 150.5 40.2 2.5e-29 102.5 9.5 3.7 4 0 0 4 4 4 2 ABC transporter transmembrane region AAA_23 PF13476.1 KND98565.1 - 2e-10 41.3 7.8 7.4e-06 26.4 0.1 3.5 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.1 KND98565.1 - 8.4e-10 39.0 5.9 9.5e-05 22.4 0.2 4.2 3 1 0 3 3 2 2 AAA domain SMC_N PF02463.14 KND98565.1 - 5.1e-07 29.1 5.6 0.01 15.0 1.9 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KND98565.1 - 7.3e-07 28.6 0.1 0.0081 15.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KND98565.1 - 6.1e-06 26.3 0.1 0.037 14.0 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain DUF258 PF03193.11 KND98565.1 - 6.6e-06 25.4 0.0 0.011 14.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 KND98565.1 - 3.8e-05 24.1 0.1 0.51 10.8 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 KND98565.1 - 8.8e-05 22.4 0.0 0.23 11.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 KND98565.1 - 0.00025 21.8 0.0 1.1 10.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KND98565.1 - 0.00028 21.0 0.3 2.3 8.3 0.0 3.3 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KND98565.1 - 0.00029 19.9 0.0 0.57 9.2 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 KND98565.1 - 0.00037 19.9 0.0 0.091 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KND98565.1 - 0.0012 17.8 0.0 0.18 10.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.24 KND98565.1 - 0.013 15.7 0.2 6.5 6.9 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 KND98565.1 - 0.015 14.9 0.3 5.5 6.6 0.1 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 KND98565.1 - 0.018 14.8 1.1 2.4 7.9 0.1 2.7 2 0 0 2 2 2 0 Dynamin family AAA_10 PF12846.2 KND98565.1 - 0.021 14.2 0.0 0.75 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain Adeno_IVa2 PF02456.10 KND98565.1 - 0.022 13.4 0.0 0.28 9.7 0.0 2.4 3 0 0 3 3 3 0 Adenovirus IVa2 protein Arch_ATPase PF01637.13 KND98565.1 - 0.023 14.3 0.2 0.42 10.2 0.0 2.6 2 1 0 2 2 2 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 KND98565.1 - 0.023 14.1 0.1 3.4 7.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 KND98565.1 - 0.049 13.1 0.1 6.9 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KND98565.1 - 0.069 13.0 0.1 19 5.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.12 KND98565.1 - 0.091 12.2 0.1 34 3.8 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 KND98565.1 - 0.13 11.0 0.0 0.27 9.9 0.0 1.5 1 0 0 1 1 1 0 ArgK protein cobW PF02492.14 KND98565.1 - 0.14 11.6 1.6 1.7 8.0 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KND98565.1 - 0.14 12.0 0.0 8 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KND98565.1 - 0.14 12.4 0.5 16 5.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KND98565.1 - 0.19 11.5 0.1 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain DUF87 PF01935.12 KND98565.1 - 2.4 7.9 6.5 1.7 8.3 0.1 2.7 3 0 0 3 3 2 0 Domain of unknown function DUF87 AA_permease_2 PF13520.1 KND98566.1 - 1.8e-66 224.4 37.0 2.2e-66 224.1 25.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KND98566.1 - 1.9e-11 42.9 33.0 3e-11 42.3 22.9 1.2 1 0 0 1 1 1 1 Amino acid permease NdhL PF10716.4 KND98566.1 - 0.002 17.8 6.7 0.51 10.1 0.1 3.8 3 0 0 3 3 3 2 NADH dehydrogenase transmembrane subunit Mito_carr PF00153.22 KND98568.1 - 1.2e-58 194.7 3.5 2.7e-20 71.8 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TUG-UBL1 PF11470.3 KND98569.1 - 0.0086 15.9 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 GLUT4 regulating protein TUG Peptidase_M22 PF00814.20 KND98570.1 - 5.2e-52 176.9 0.0 9e-52 176.1 0.0 1.3 1 1 0 1 1 1 1 Glycoprotease family Nse4_C PF08743.5 KND98571.1 - 9.5e-24 83.2 0.0 2.7e-23 81.8 0.0 1.8 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 KND98571.1 - 1.4e-08 34.4 0.1 2.9e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Cas_DxTHG PF09455.5 KND98571.1 - 0.0038 16.4 1.1 0.0054 15.9 0.8 1.3 1 0 0 1 1 1 1 CRISPR-associated (Cas) DxTHG family Ino80_Iec3 PF14612.1 KND98571.1 - 0.0054 16.8 0.2 0.011 15.8 0.2 1.5 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling DNA_mis_repair PF01119.14 KND98572.1 - 2.3e-31 107.7 0.0 3.8e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KND98572.1 - 6.6e-10 38.7 0.0 1.4e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KND98572.1 - 2.5e-09 36.8 0.0 5.9e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_8 PF13181.1 KND98574.1 - 2.2e-08 33.3 3.9 0.096 12.5 0.0 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KND98574.1 - 6.4e-07 29.4 0.1 2.1 9.1 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KND98574.1 - 1e-05 26.0 1.1 5.4 7.8 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 KND98574.1 - 0.00077 18.9 0.1 2.1 8.1 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KND98574.1 - 0.0026 17.4 0.1 2 8.3 0.2 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KND98574.1 - 0.006 16.8 0.3 5.7 7.3 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KND98574.1 - 0.0067 16.3 1.9 3 7.8 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat SPOB_a PF14689.1 KND98574.1 - 0.037 13.5 2.4 2.3 7.8 0.1 3.4 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_2 PF07719.12 KND98574.1 - 0.2 11.6 11.8 1.3 9.0 0.0 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.1 KND98574.1 - 0.23 11.1 11.3 1.1 8.9 0.0 4.8 6 0 0 6 6 6 0 TPR repeat Apc3 PF12895.2 KND98574.1 - 0.24 11.5 9.5 0.59 10.3 0.1 4.5 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 SUI1 PF01253.17 KND98575.1 - 3.5e-19 68.3 2.2 3.5e-19 68.3 1.6 1.9 1 1 0 1 1 1 1 Translation initiation factor SUI1 MoCF_biosynth PF00994.19 KND98575.1 - 0.024 14.0 1.4 0.051 12.9 0.4 1.9 1 1 1 2 2 2 0 Probable molybdopterin binding domain TnpV PF14198.1 KND98575.1 - 0.34 10.8 4.9 0.1 12.5 0.7 1.9 2 0 0 2 2 2 0 Transposon-encoded protein TnpV PIN_2 PF10130.4 KND98575.1 - 0.37 10.8 5.6 1.7 8.6 3.9 2.1 1 1 0 1 1 1 0 PIN domain DUF3759 PF12585.3 KND98575.1 - 0.98 9.3 8.4 0.31 10.9 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3759) Cgr1 PF03879.9 KND98575.1 - 2.8 8.1 23.7 0.049 13.8 8.7 2.2 2 0 0 2 2 2 0 Cgr1 family TPR_12 PF13424.1 KND98576.1 - 0.0056 16.5 0.1 0.016 15.1 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 KND98576.1 - 0.016 15.3 0.0 0.063 13.5 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Zn_clus PF00172.13 KND98577.1 - 2e-08 34.0 5.7 3.5e-08 33.2 4.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arch_ATPase PF01637.13 KND98579.1 - 7.1e-07 29.1 0.1 7.1e-07 29.1 0.1 2.6 4 0 0 4 4 4 1 Archaeal ATPase AAA_16 PF13191.1 KND98579.1 - 1.4e-06 28.3 0.0 2.9e-05 24.1 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 KND98579.1 - 0.00025 20.7 0.0 0.0088 15.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MobB PF03205.9 KND98579.1 - 0.00047 19.8 0.0 0.0021 17.7 0.0 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 KND98579.1 - 0.0018 17.8 0.0 0.0027 17.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_11 PF13086.1 KND98579.1 - 0.0019 17.8 1.7 0.88 9.0 0.0 2.7 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KND98579.1 - 0.0026 17.9 0.0 0.0077 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KND98579.1 - 0.003 16.9 0.0 0.0087 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KND98579.1 - 0.0061 16.7 0.1 0.018 15.2 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 KND98579.1 - 0.016 13.9 0.0 0.031 12.9 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus Miro PF08477.8 KND98579.1 - 0.026 15.0 0.0 0.18 12.3 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein Abi_2 PF07751.6 KND98579.1 - 0.038 14.1 1.4 0.14 12.3 0.0 2.4 2 0 0 2 2 2 0 Abi-like protein Folate_carrier PF01770.13 KND98579.1 - 0.063 11.7 0.0 0.14 10.6 0.0 1.5 1 0 0 1 1 1 0 Reduced folate carrier T2SE PF00437.15 KND98579.1 - 0.066 12.1 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 KND98579.1 - 0.072 12.1 0.1 0.072 12.1 0.1 1.8 2 0 0 2 2 1 0 KaiC NACHT PF05729.7 KND98579.1 - 0.093 12.3 0.5 0.33 10.5 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.1 KND98579.1 - 0.11 12.0 0.1 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GLTSCR1 PF15249.1 KND98579.1 - 0.13 12.3 0.0 0.13 12.3 0.0 3.3 4 0 0 4 4 3 0 Glioma tumor suppressor candidate region HECT PF00632.20 KND98581.1 - 8.1e-83 278.1 0.3 1.4e-82 277.4 0.2 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 KND98581.1 - 0.016 14.8 0.0 0.045 13.4 0.0 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF4050 PF13259.1 KND98581.1 - 0.15 11.9 0.6 0.32 10.9 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) Hydrolase_6 PF13344.1 KND98583.1 - 1.2e-27 95.6 0.0 2.4e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KND98583.1 - 6.5e-08 32.1 0.0 2e-07 30.6 0.0 1.9 2 1 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 KND98583.1 - 3.3e-06 27.6 0.0 0.14 12.5 0.0 2.7 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KND98583.1 - 0.00048 20.4 0.0 0.23 11.6 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Arf PF00025.16 KND98584.1 - 0.084 12.1 0.4 0.31 10.2 0.1 1.9 1 1 1 2 2 2 0 ADP-ribosylation factor family UPF0236 PF06782.6 KND98584.1 - 0.1 11.0 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0236) Bul1_N PF04425.7 KND98585.1 - 0.046 12.2 1.0 0.06 11.9 0.7 1.1 1 0 0 1 1 1 0 Bul1 N terminus SHOCT PF09851.4 KND98585.1 - 0.21 11.0 1.5 0.59 9.6 1.0 1.8 1 0 0 1 1 1 0 Short C-terminal domain Rpp20 PF12328.3 KND98586.1 - 2.3e-26 92.1 0.4 3.1e-26 91.7 0.3 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 KND98586.1 - 2.6e-13 49.3 0.3 3.8e-13 48.8 0.2 1.3 1 0 0 1 1 1 1 Alba EF-hand_1 PF00036.27 KND98586.1 - 0.087 12.1 0.1 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 EF hand 5_3_exonuc_N PF02739.11 KND98586.1 - 0.09 12.1 0.0 0.13 11.6 0.0 1.3 1 1 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain Ribosomal_L24e PF01246.15 KND98589.1 - 1.1e-16 60.4 2.3 1.1e-16 60.4 1.6 2.3 2 0 0 2 2 2 1 Ribosomal protein L24e Trypan_PARP PF05887.6 KND98589.1 - 0.071 12.9 2.6 0.099 12.4 1.8 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Cut8_N PF14482.1 KND98589.1 - 0.077 13.0 0.2 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 Cut8 proteasome-binding domain Pam16 PF03656.8 KND98590.1 - 3.2e-07 30.1 0.0 4e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.26 KND98590.1 - 1.5e-06 27.8 0.0 2.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain ANTH PF07651.11 KND98592.1 - 4.3e-63 212.6 0.7 4.3e-63 212.6 0.5 2.6 3 0 0 3 3 3 1 ANTH domain ENTH PF01417.15 KND98592.1 - 2.9e-07 30.3 0.1 2.9e-07 30.3 0.1 2.5 3 0 0 3 3 3 1 ENTH domain AAA_23 PF13476.1 KND98592.1 - 0.0033 17.7 22.3 0.0033 17.7 15.4 2.8 3 0 0 3 3 3 1 AAA domain Glyco_hydro_16 PF00722.16 KND98593.1 - 9.2e-47 158.7 0.5 9.2e-47 158.7 0.4 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF605 PF04652.11 KND98593.1 - 0.99 8.7 22.7 1.6 8.0 15.8 1.2 1 0 0 1 1 1 0 Vta1 like Tox-REase-3 PF15647.1 KND98594.1 - 0.018 14.8 0.1 0.019 14.7 0.1 1.1 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 3 Siah-Interact_N PF09032.6 KND98594.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.0 1 0 0 1 1 1 0 Siah interacting protein, N terminal She9_MDM33 PF05546.6 KND98594.1 - 0.11 11.9 0.0 0.12 11.9 0.0 1.0 1 0 0 1 1 1 0 She9 / Mdm33 family Rhodanese PF00581.15 KND98597.1 - 1.9e-12 47.5 0.0 2.2e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain CTP_transf_2 PF01467.21 KND98599.1 - 2.3e-25 89.4 0.0 4.3e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase DUF2404 PF10296.4 KND98600.1 - 4.3e-08 33.1 0.0 7.6e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) RIO1 PF01163.17 KND98601.1 - 5.3e-08 32.4 0.0 1.8e-07 30.7 0.0 1.8 1 1 0 1 1 1 1 RIO1 family APH PF01636.18 KND98601.1 - 6.3e-08 32.6 0.0 0.00027 20.7 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KND98601.1 - 2.9e-07 29.7 0.0 5.7e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KND98601.1 - 3.2e-05 23.2 0.0 3.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WaaY PF06176.6 KND98601.1 - 0.00072 18.8 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) EcKinase PF02958.15 KND98601.1 - 0.0014 17.7 0.1 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase_Tyr PF07714.12 KND98601.1 - 0.014 14.4 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Choline_kinase PF01633.15 KND98601.1 - 0.16 11.5 0.2 0.28 10.7 0.1 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase CLTH PF10607.4 KND98602.1 - 1.7e-12 47.2 6.4 3.2e-12 46.3 3.4 2.3 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 KND98602.1 - 0.0067 16.5 0.6 0.033 14.2 0.4 2.2 1 1 0 1 1 1 1 SPRY domain DHFR_2 PF06442.6 KND98602.1 - 0.019 14.5 0.1 0.049 13.2 0.1 1.6 1 0 0 1 1 1 0 R67 dihydrofolate reductase HHH PF00633.18 KND98603.1 - 0.024 14.3 0.3 0.06 13.0 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif 60KD_IMP PF02096.15 KND98604.1 - 3.7e-18 65.9 0.6 5.1e-18 65.4 0.4 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Spt4 PF06093.8 KND98605.1 - 1.5e-28 98.5 0.0 2.1e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger AAA PF00004.24 KND98606.1 - 2.6e-51 173.2 0.0 1.6e-42 144.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KND98606.1 - 3.7e-07 30.3 0.9 1e-05 25.5 0.0 3.3 3 1 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.1 KND98606.1 - 6.7e-06 26.2 0.1 0.0027 17.8 0.1 3.6 2 1 0 2 2 2 1 AAA domain Bromodomain PF00439.20 KND98606.1 - 1e-05 25.3 0.1 3.1e-05 23.8 0.1 1.8 1 0 0 1 1 1 1 Bromodomain AAA_2 PF07724.9 KND98606.1 - 1.5e-05 24.9 0.0 6.5e-05 22.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 KND98606.1 - 2.5e-05 23.7 0.0 0.00061 19.2 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 KND98606.1 - 0.00024 21.1 0.0 0.39 10.7 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.9 KND98606.1 - 0.00046 19.9 0.0 0.0027 17.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KND98606.1 - 0.0025 17.7 0.0 0.008 16.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND98606.1 - 0.006 16.3 0.0 0.023 14.4 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 KND98606.1 - 0.0095 15.3 0.1 0.046 13.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 KND98606.1 - 0.0095 15.4 0.0 1.8 8.0 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_33 PF13671.1 KND98606.1 - 0.0097 15.7 0.0 0.038 13.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KND98606.1 - 0.013 14.6 0.2 0.1 11.7 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.12 KND98606.1 - 0.015 14.1 0.0 0.61 8.9 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 TIP49 PF06068.8 KND98606.1 - 0.016 13.9 0.0 0.053 12.2 0.0 1.7 2 0 0 2 2 2 0 TIP49 C-terminus ABC_tran PF00005.22 KND98606.1 - 0.019 15.2 0.0 0.23 11.7 0.0 2.9 2 0 0 2 2 2 0 ABC transporter ResIII PF04851.10 KND98606.1 - 0.02 14.6 0.1 0.23 11.2 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 KND98606.1 - 0.023 14.8 0.0 0.091 12.9 0.0 2.1 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.11 KND98606.1 - 0.058 12.6 0.0 0.31 10.2 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein RuvB_N PF05496.7 KND98606.1 - 0.074 12.0 0.0 0.22 10.5 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KND98606.1 - 0.078 13.7 0.0 0.078 13.7 0.0 4.1 4 1 0 4 4 2 0 AAA domain Sedlin_N PF04628.8 KND98606.1 - 0.11 12.4 0.2 0.28 11.0 0.0 1.8 2 0 0 2 2 1 0 Sedlin, N-terminal conserved region AAA_18 PF13238.1 KND98606.1 - 0.17 12.2 0.0 0.17 12.2 0.0 3.5 4 0 0 4 4 1 0 AAA domain tRNA-synt_1g PF09334.6 KND98608.1 - 9.7e-104 347.1 1.9 2.6e-103 345.6 1.3 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KND98608.1 - 6.1e-22 77.3 2.5 1.2e-13 49.9 0.0 4.0 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 KND98608.1 - 1.8e-06 27.3 1.0 0.0021 17.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 KND98608.1 - 0.00044 20.0 0.1 0.0011 18.7 0.1 1.7 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA Yip1 PF04893.12 KND98609.1 - 5.2e-10 39.0 12.6 8.4e-10 38.4 8.7 1.3 1 0 0 1 1 1 1 Yip1 domain GDPD PF03009.12 KND98610.1 - 4.6e-73 245.8 0.0 1.3e-72 244.3 0.0 1.8 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 KND98610.1 - 9.1e-23 80.4 0.4 2.7e-06 27.6 0.5 4.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 KND98610.1 - 8.7e-20 69.4 4.0 0.00012 21.6 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat SPX PF03105.14 KND98610.1 - 3.9e-19 69.4 14.7 2.4e-13 50.4 2.4 4.1 2 1 1 3 3 3 2 SPX domain Ank_4 PF13637.1 KND98610.1 - 1.2e-15 57.4 0.4 0.00043 20.7 0.0 4.5 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND98610.1 - 2e-14 52.2 2.2 0.022 14.9 0.0 7.0 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 KND98610.1 - 1.4e-12 47.4 0.9 0.00027 21.0 0.1 5.0 4 1 1 5 5 5 3 Ankyrin repeats (many copies) DUF1509 PF07420.6 KND98610.1 - 0.15 11.2 1.7 0.25 10.5 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) TIP41 PF04176.8 KND98612.1 - 7e-72 240.4 0.0 9.7e-72 240.0 0.0 1.2 1 0 0 1 1 1 1 TIP41-like family Serglycin PF04360.7 KND98612.1 - 0.027 14.1 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Serglycin Sod_Fe_C PF02777.13 KND98613.1 - 1.7e-14 53.5 0.1 2.3e-06 27.3 0.1 2.5 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Fib_alpha PF08702.5 KND98614.1 - 0.01 15.9 1.5 0.024 14.7 0.2 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TPR_2 PF07719.12 KND98616.1 - 6.6e-06 25.6 1.4 0.0065 16.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KND98616.1 - 0.0026 17.7 0.1 0.15 12.3 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KND98616.1 - 0.0038 16.7 0.0 0.13 11.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KND98616.1 - 0.024 14.2 0.9 0.55 9.9 0.1 2.6 3 0 0 3 3 3 0 TPR repeat TPR_14 PF13428.1 KND98616.1 - 0.086 13.5 1.2 4.6 8.1 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KND98616.1 - 0.13 13.0 0.2 0.13 13.0 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KND98616.1 - 0.15 11.8 0.9 3.6 7.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat CTP_synth_N PF06418.9 KND98617.1 - 3.1e-117 390.5 0.3 4.8e-117 389.9 0.2 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KND98617.1 - 3.5e-52 176.6 0.0 5.2e-52 176.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KND98617.1 - 1.9e-06 27.4 0.0 7.1e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.18 KND98617.1 - 0.0041 16.5 0.0 0.013 14.9 0.0 1.8 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ESCRT-II PF05871.7 KND98619.1 - 1.8e-39 134.8 0.2 3.1e-39 134.0 0.0 1.4 2 0 0 2 2 2 1 ESCRT-II complex subunit SCA7 PF08313.7 KND98621.1 - 0.0089 15.6 0.3 0.0089 15.6 0.2 1.7 2 0 0 2 2 2 1 SCA7, zinc-binding domain F-box-like PF12937.2 KND98623.1 - 5.1e-11 42.1 0.8 1.1e-10 41.0 0.6 1.6 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KND98623.1 - 1.8e-07 30.7 7.1 0.14 11.9 0.0 5.9 4 2 1 6 6 6 4 Leucine rich repeat LRR_4 PF12799.2 KND98623.1 - 7.8e-07 28.5 7.8 1.3 8.7 0.0 6.8 6 1 1 7 7 7 3 Leucine Rich repeats (2 copies) F-box PF00646.28 KND98623.1 - 1.2e-06 28.0 1.2 4.1e-06 26.2 0.8 2.0 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 KND98623.1 - 0.018 14.9 0.0 0.08 12.9 0.0 2.1 1 0 0 1 1 1 0 PRANC domain F-box-like_2 PF13013.1 KND98623.1 - 0.032 13.9 3.3 1 9.1 2.3 3.1 1 1 0 1 1 1 0 F-box-like domain DMA PF03474.9 KND98623.1 - 0.093 12.5 0.2 0.33 10.8 0.1 2.0 1 0 0 1 1 1 0 DMRTA motif PUF PF00806.14 KND98624.1 - 5.4e-22 75.9 3.1 4.5e-07 28.9 0.0 6.2 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat Peptidase_U35_2 PF14550.1 KND98624.1 - 0.053 13.1 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Putative phage protease XkdF DUF3655 PF12379.3 KND98626.1 - 6.1 6.8 11.1 32 4.5 4.9 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3655) PCI PF01399.22 KND98627.1 - 6.6e-15 55.3 2.4 3.8e-14 52.8 1.6 2.3 1 1 0 1 1 1 1 PCI domain eIF-5_eIF-2B PF01873.12 KND98628.1 - 5.5e-37 126.2 0.0 9.5e-37 125.4 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 KND98628.1 - 2.9e-26 91.2 0.5 2.9e-26 91.2 0.4 2.7 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Anillin PF08174.6 KND98629.1 - 6.5e-16 58.6 1.6 6.6e-15 55.3 0.1 3.3 2 1 0 2 2 2 1 Cell division protein anillin PH PF00169.24 KND98629.1 - 1.3e-09 38.2 0.2 4.3e-09 36.5 0.1 2.0 1 0 0 1 1 1 1 PH domain DUF1282 PF06930.7 KND98631.1 - 0.12 11.9 0.0 0.15 11.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Suf PF05843.9 KND98631.1 - 0.35 10.5 3.0 0.39 10.3 2.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Recep_L_domain PF01030.19 KND98633.1 - 1.9e-10 40.6 10.0 0.0069 16.3 1.1 4.5 2 1 2 4 4 4 4 Receptor L domain Dockerin_1 PF00404.13 KND98633.1 - 0.32 10.7 4.9 0.59 9.9 0.5 3.2 3 0 0 3 3 3 0 Dockerin type I repeat Macoilin PF09726.4 KND98633.1 - 2.4 6.3 10.1 3.2 5.9 7.0 1.2 1 0 0 1 1 1 0 Transmembrane protein UDPGP PF01704.13 KND98634.1 - 1.3e-44 152.3 0.0 1.7e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 KND98634.1 - 0.006 16.6 0.0 0.013 15.6 0.0 1.8 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 KND98634.1 - 0.08 12.2 0.4 0.55 9.4 0.3 2.1 1 1 0 1 1 1 0 Nucleotidyl transferase NPV_P10 PF05531.7 KND98636.1 - 0.36 11.1 5.5 2.1 8.6 0.2 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein APO_RNA-bind PF05634.6 KND98637.1 - 0.22 10.7 1.4 0.2 10.8 1.0 1.1 1 0 0 1 1 1 0 APO RNA-binding HAD_2 PF13419.1 KND98641.1 - 6.5e-16 59.0 0.0 1.8e-15 57.5 0.0 1.7 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KND98641.1 - 4.4e-08 32.7 0.2 8.3e-08 31.8 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KND98641.1 - 5.2e-07 30.2 0.0 5.9e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KND98641.1 - 0.0084 16.2 0.0 0.019 15.1 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KND98641.1 - 0.04 13.8 0.1 0.41 10.5 0.1 2.3 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase PITH PF06201.8 KND98645.1 - 4.7e-42 143.3 1.2 5.8e-42 143.0 0.8 1.1 1 0 0 1 1 1 1 PITH domain His_Phos_1 PF00300.17 KND98647.1 - 5.1e-41 140.4 0.0 6.5e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Nsp1_C PF05064.8 KND98648.1 - 5.9e-32 109.7 8.8 5.9e-32 109.7 6.1 1.8 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 KND98648.1 - 1.8e-19 70.0 226.5 3.3e-09 36.9 17.8 8.5 2 1 7 9 9 9 6 Nucleoporin FG repeat region SHIPPO-rpt PF07004.7 KND98648.1 - 0.00088 20.0 54.5 57 4.8 0.2 14.2 7 2 1 8 8 8 0 Sperm-tail PG-rich repeat APG6 PF04111.7 KND98648.1 - 5.9 5.8 11.3 0.44 9.5 4.3 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 PQ-loop PF04193.9 KND98649.1 - 1.2e-17 63.1 1.5 9.6e-11 41.0 0.2 3.4 2 1 0 2 2 2 2 PQ loop repeat VMA21 PF09446.5 KND98649.1 - 0.092 12.6 1.5 2.2 8.2 0.1 2.7 1 1 1 2 2 2 0 VMA21-like domain ALAD PF00490.16 KND98650.1 - 2.8e-109 364.9 0.0 3.4e-109 364.6 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase PucR PF07905.6 KND98650.1 - 0.02 14.4 0.1 6.4 6.3 0.0 2.3 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family Tetraspannin PF00335.15 KND98650.1 - 0.13 11.5 0.2 0.51 9.5 0.0 1.9 2 0 0 2 2 2 0 Tetraspanin family DUF3687 PF12459.3 KND98650.1 - 0.39 9.9 7.8 0.84 8.9 5.4 1.5 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein Snf7 PF03357.16 KND98652.1 - 4.2e-30 104.3 13.4 4.9e-30 104.1 9.3 1.0 1 0 0 1 1 1 1 Snf7 Cactin_mid PF10312.4 KND98652.1 - 0.027 13.7 4.4 0.056 12.7 3.1 1.5 1 0 0 1 1 1 0 Conserved mid region of cactin RNA_binding PF01877.12 KND98652.1 - 0.52 10.3 7.5 3.7 7.5 2.7 2.5 1 1 1 2 2 2 0 RNA binding DUF4094 PF13334.1 KND98652.1 - 9.9 6.6 8.9 17 5.8 0.2 3.3 2 2 2 4 4 4 0 Domain of unknown function (DUF4094) TetR_C_5 PF08360.6 KND98653.1 - 0.063 13.2 0.2 0.063 13.2 0.2 1.1 1 0 0 1 1 1 0 QacR-like protein, C-terminal region DUF866 PF05907.8 KND98653.1 - 0.11 11.9 0.0 0.12 11.8 0.0 1.2 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) WD40 PF00400.27 KND98654.1 - 9.6e-19 66.5 7.8 0.00049 19.8 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat GYF PF02213.11 KND98655.1 - 0.036 13.6 0.0 0.039 13.5 0.0 1.0 1 0 0 1 1 1 0 GYF domain Pkinase PF00069.20 KND98656.1 - 2.7e-70 236.4 0.0 3.4e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND98656.1 - 1.2e-30 106.4 0.0 1.8e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND98656.1 - 7.3e-05 21.8 0.0 0.0047 15.9 0.0 2.5 2 1 0 3 3 3 1 Kinase-like Kdo PF06293.9 KND98656.1 - 0.00015 20.8 0.1 0.00073 18.6 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KND98656.1 - 0.00026 20.8 1.0 0.029 14.1 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 KND98656.1 - 0.065 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Rgp1 PF08737.5 KND98657.1 - 4.6e-60 203.8 0.0 5.7e-60 203.5 0.0 1.1 1 0 0 1 1 1 1 Rgp1 Mito_carr PF00153.22 KND98661.1 - 3.5e-70 231.7 1.8 5.1e-22 77.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Scramblase PF03803.10 KND98662.1 - 1.4e-62 210.6 0.0 1.8e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Scramblase Peptidase_C12 PF01088.16 KND98663.1 - 1.4e-41 141.9 0.0 2.4e-41 141.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Thioredoxin PF00085.15 KND98664.1 - 1.4e-21 76.1 0.1 1.2e-20 73.1 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 KND98664.1 - 1.1e-07 31.9 0.0 1.6e-05 24.9 0.0 2.8 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KND98664.1 - 2.2e-05 24.6 0.1 0.00011 22.4 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 KND98664.1 - 0.0015 18.2 0.0 0.025 14.2 0.0 2.4 2 1 0 2 2 2 1 AhpC/TSA family Thioredoxin_9 PF14595.1 KND98664.1 - 0.0044 16.5 0.0 0.017 14.6 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin Redoxin PF08534.5 KND98664.1 - 0.0059 16.1 0.1 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Redoxin TraF PF13728.1 KND98664.1 - 0.024 14.1 0.0 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 F plasmid transfer operon protein FSH1 PF03959.8 KND98665.1 - 2.8e-54 183.7 0.0 2.5e-53 180.6 0.0 1.9 1 1 1 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KND98665.1 - 0.0094 15.7 0.0 0.016 14.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KND98665.1 - 0.15 11.5 0.2 6.5 6.1 0.2 2.3 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase HAD_2 PF13419.1 KND98666.1 - 1e-24 87.7 0.2 1.4e-24 87.2 0.2 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Atg14 PF10186.4 KND98667.1 - 0.097 11.6 1.0 0.35 9.7 0.1 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ATP-synt_E_2 PF08112.6 KND98667.1 - 0.25 11.4 2.1 0.82 9.7 1.4 1.9 1 0 0 1 1 1 0 ATP synthase epsilon subunit Peptidase_M20 PF01546.23 KND98668.1 - 1.7e-30 105.9 0.0 2.6e-30 105.3 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KND98668.1 - 1.2e-13 50.7 0.0 1.9e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KND98668.1 - 0.03 14.0 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 IF4E PF01652.13 KND98669.1 - 3.3e-36 124.2 0.2 7.5e-36 123.1 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic initiation factor 4E FAIM1 PF06905.8 KND98669.1 - 0.13 11.4 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) Sulfolobus_pRN PF05584.6 KND98671.1 - 0.17 11.8 0.5 0.15 12.0 0.3 1.0 1 0 0 1 1 1 0 Sulfolobus plasmid regulatory protein Zn_clus PF00172.13 KND98672.1 - 2.1e-05 24.2 7.5 3.7e-05 23.5 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND98672.1 - 2.2e-05 23.5 3.9 2.2e-05 23.5 2.7 2.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain AdoHcyase PF05221.12 KND98674.1 - 6.7e-139 461.3 0.0 7.7e-139 461.1 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 KND98674.1 - 3.5e-83 277.3 3.0 5.8e-83 276.6 2.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KND98674.1 - 8.2e-08 31.5 1.1 3.8e-07 29.4 0.1 2.3 2 1 1 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 KND98674.1 - 0.0087 15.4 0.2 0.015 14.6 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ELFV_dehydrog PF00208.16 KND98674.1 - 0.029 13.9 0.8 0.081 12.4 0.3 1.8 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.13 KND98674.1 - 0.053 13.5 0.1 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain TMEM107 PF14995.1 KND98674.1 - 0.067 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein IMS_HHH PF11798.3 KND98675.1 - 0.037 14.0 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 IMS family HHH motif Ribonuclease_T2 PF00445.13 KND98676.1 - 2.9e-41 141.1 2.0 2.9e-41 141.1 1.4 1.4 2 0 0 2 2 2 1 Ribonuclease T2 family Adaptin_N PF01602.15 KND98678.1 - 8.8e-73 245.4 1.2 1.1e-72 245.0 0.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KND98678.1 - 0.00012 22.2 10.2 0.045 14.0 2.1 4.9 3 2 3 6 6 6 4 HEAT repeats HEAT PF02985.17 KND98678.1 - 0.00053 19.8 1.2 0.27 11.4 0.0 3.9 4 0 0 4 4 4 1 HEAT repeat BUD22 PF09073.5 KND98678.1 - 0.39 9.7 21.5 0.58 9.1 14.9 1.3 1 0 0 1 1 1 0 BUD22 Gal-3-0_sulfotr PF06990.6 KND98679.1 - 0.033 12.8 0.2 0.046 12.3 0.1 1.1 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase Gpi16 PF04113.9 KND98680.1 - 9.5e-187 621.4 0.0 1.1e-186 621.2 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Mad3_BUB1_I PF08311.7 KND98681.1 - 7e-42 142.1 0.1 1.4e-41 141.2 0.1 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.6 KND98681.1 - 5.4e-09 35.8 0.0 1.5e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Pyr_redox_2 PF07992.9 KND98682.1 - 6.2e-11 42.5 0.0 1.1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND98682.1 - 1.1e-09 38.5 0.1 9e-07 29.2 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KND98682.1 - 2.1e-06 27.9 0.1 0.0029 17.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KND98682.1 - 3.9e-06 26.0 0.0 2.6e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KND98682.1 - 1.8e-05 24.5 0.2 0.35 10.6 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 KND98682.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.7 KND98682.1 - 0.017 14.0 0.1 0.065 12.1 0.0 2.0 3 0 0 3 3 3 0 Lycopene cyclase protein Ldh_1_N PF00056.18 KND98682.1 - 0.094 12.5 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KND98682.1 - 0.16 10.9 0.0 6.9 5.6 0.0 2.5 2 0 0 2 2 2 0 FAD binding domain Hydrolase PF00702.21 KND98683.1 - 1.5e-15 58.2 1.6 3.8e-11 43.7 0.7 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KND98683.1 - 5.5e-15 55.0 0.0 1.7e-14 53.4 0.0 1.9 1 1 1 2 2 2 1 E1-E2 ATPase HAD PF12710.2 KND98683.1 - 6.9e-14 52.4 2.7 7e-13 49.1 1.9 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KND98683.1 - 4.1e-11 42.7 0.0 1.2e-10 41.2 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KND98683.1 - 0.00065 19.3 3.2 0.0015 18.1 0.7 2.8 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase VTC PF09359.5 KND98684.1 - 1.4e-104 349.1 1.4 2e-104 348.6 0.0 1.9 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 KND98684.1 - 1e-22 81.2 29.0 2.7e-21 76.5 13.2 4.0 2 2 1 3 3 3 1 SPX domain DUF202 PF02656.10 KND98684.1 - 1.9e-11 44.0 3.7 4.2e-11 42.8 2.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Herpes_UL25 PF01499.11 KND98684.1 - 0.02 13.2 0.4 0.036 12.3 0.3 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family LXG PF04740.7 KND98684.1 - 0.047 13.4 11.6 0.36 10.5 0.2 3.7 2 1 2 4 4 4 0 LXG domain of WXG superfamily Baculo_PEP_C PF04513.7 KND98684.1 - 0.049 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TroA PF01297.12 KND98684.1 - 0.054 12.7 2.9 0.12 11.5 0.4 2.2 2 0 0 2 2 2 0 Periplasmic solute binding protein family Syntaxin-6_N PF09177.6 KND98684.1 - 0.072 13.5 0.5 0.072 13.5 0.3 3.0 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Fzo_mitofusin PF04799.8 KND98684.1 - 0.99 8.7 6.4 1 8.6 1.5 2.4 2 0 0 2 2 2 0 fzo-like conserved region hDGE_amylase PF14701.1 KND98684.1 - 4.8 5.9 8.8 0.68 8.7 3.1 1.6 2 0 0 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme DAO PF01266.19 KND98687.1 - 1e-51 175.9 0.0 1.2e-51 175.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND98687.1 - 7.5e-06 25.8 0.0 1.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KND98687.1 - 0.00053 20.3 0.2 0.0034 17.7 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KND98687.1 - 0.0079 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 KND98687.1 - 0.0099 14.8 0.2 0.05 12.5 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KND98687.1 - 0.011 15.7 0.2 0.13 12.3 0.1 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KND98687.1 - 0.032 14.2 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_2 PF00890.19 KND98687.1 - 0.043 12.6 0.2 0.059 12.2 0.1 1.4 1 1 0 1 1 1 0 FAD binding domain GMC_oxred_N PF00732.14 KND98687.1 - 0.054 12.6 0.0 0.096 11.8 0.0 1.4 1 0 0 1 1 1 0 GMC oxidoreductase Pyr_redox_2 PF07992.9 KND98687.1 - 0.15 11.9 0.4 0.3 10.9 0.3 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.20 KND98688.1 - 3.3e-69 232.9 0.0 3.8e-69 232.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND98688.1 - 1.2e-29 103.2 0.0 2e-29 102.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND98688.1 - 0.00064 18.7 0.0 0.00091 18.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KND98688.1 - 0.0023 17.7 0.1 0.0059 16.3 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family SH3_1 PF00018.23 KND98689.1 - 4e-08 32.5 0.4 8.7e-08 31.4 0.3 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KND98689.1 - 1.4e-05 24.4 0.2 2.7e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KND98689.1 - 0.00013 21.4 0.1 0.00031 20.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Transglut_core PF01841.14 KND98689.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF3925 PF13063.1 KND98690.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3925) Cpn60_TCP1 PF00118.19 KND98691.1 - 6.9e-157 522.9 2.2 7.9e-157 522.7 1.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RINT1_TIP1 PF04437.8 KND98692.1 - 5e-49 167.1 10.5 6.5e-49 166.7 7.3 1.1 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Pkinase PF00069.20 KND98694.1 - 1e-68 231.3 0.0 1.3e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND98694.1 - 9.1e-32 110.1 0.0 1.1e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KND98694.1 - 1.3e-15 57.2 0.0 3.2e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KND98694.1 - 0.00059 18.8 0.8 2.3 7.0 0.1 3.4 2 1 1 3 3 3 3 Kinase-like Kdo PF06293.9 KND98694.1 - 0.0017 17.4 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KND98694.1 - 0.067 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family TPR_11 PF13414.1 KND98695.1 - 5.1e-07 29.2 1.4 0.01 15.4 0.1 3.4 3 2 1 4 4 4 2 TPR repeat Sel1 PF08238.7 KND98695.1 - 3.4e-05 24.3 0.0 8.7 7.1 0.0 4.6 4 0 0 4 4 4 1 Sel1 repeat TPR_12 PF13424.1 KND98695.1 - 0.00028 20.7 0.3 0.45 10.4 0.1 3.0 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KND98695.1 - 0.00063 19.4 4.9 0.67 10.0 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KND98695.1 - 0.00079 19.7 0.0 2 8.7 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KND98695.1 - 0.0072 16.0 7.5 2.4 8.1 0.0 5.6 6 1 0 6 6 6 1 Tetratricopeptide repeat DUF1779 PF08680.5 KND98695.1 - 0.042 13.7 0.3 0.83 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1779) TPR_6 PF13174.1 KND98695.1 - 0.098 13.1 0.3 33 5.2 0.0 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat PRP1_N PF06424.7 KND98695.1 - 0.19 12.0 0.5 0.53 10.5 0.1 1.9 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal TPR_16 PF13432.1 KND98695.1 - 0.84 10.3 0.1 0.84 10.3 0.0 3.1 5 1 1 6 6 6 0 Tetratricopeptide repeat Homeobox PF00046.24 KND98696.1 - 2e-17 62.5 3.0 3.9e-17 61.6 2.1 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KND98696.1 - 0.0032 17.1 1.2 0.0085 15.7 0.8 1.8 1 0 0 1 1 1 1 Homeobox KN domain Transglycosylas PF06737.9 KND98696.1 - 0.068 13.4 0.2 5 7.5 0.0 2.5 2 0 0 2 2 2 0 Transglycosylase-like domain Homez PF11569.3 KND98696.1 - 0.094 11.7 0.1 0.23 10.5 0.1 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Sigma70_r4_2 PF08281.7 KND98696.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 UPF0542 PF15086.1 KND98699.1 - 0.15 11.7 0.9 0.17 11.6 0.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 TMEMspv1-c74-12 PF11044.3 KND98699.1 - 2.5 7.6 5.5 3.2 7.3 3.8 1.2 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein ATG16 PF08614.6 KND98703.1 - 1.7e-25 90.0 22.7 4.8e-22 78.7 13.2 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) SlyX PF04102.7 KND98703.1 - 0.0094 16.3 2.9 0.0094 16.3 2.0 3.5 1 1 2 3 3 3 1 SlyX APG6 PF04111.7 KND98703.1 - 0.51 9.3 14.7 0.64 9.0 10.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_1 PF00170.16 KND98703.1 - 5.6 6.9 12.2 2.9 7.9 0.3 3.4 2 1 1 3 3 3 0 bZIP transcription factor ADH_zinc_N PF00107.21 KND98704.1 - 6.7e-32 109.7 0.9 9.9e-32 109.2 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KND98704.1 - 3.5e-29 100.7 0.3 7.7e-29 99.6 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glyco_transf_22 PF03901.12 KND98707.1 - 4.5e-84 282.8 27.3 5.3e-84 282.6 18.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Calpain_III PF01067.17 KND98708.1 - 7.7e-10 38.5 0.0 6.2e-08 32.3 0.0 2.9 2 0 0 2 2 2 1 Calpain large subunit, domain III Peptidase_C2 PF00648.16 KND98708.1 - 0.00039 19.4 0.0 0.00082 18.4 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease OST3_OST6 PF04756.8 KND98709.1 - 2.3e-20 72.7 4.2 2.3e-20 72.7 2.9 1.6 2 0 0 2 2 2 1 OST3 / OST6 family Peptidase_M56 PF05569.6 KND98709.1 - 0.0047 15.9 1.8 0.0072 15.3 1.3 1.2 1 0 0 1 1 1 1 BlaR1 peptidase M56 Thioredoxin PF00085.15 KND98709.1 - 0.025 14.2 0.0 0.11 12.1 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin DUF1240 PF06836.7 KND98709.1 - 0.4 10.9 5.7 0.085 13.0 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) DUF1129 PF06570.6 KND98709.1 - 2.9 7.1 6.0 0.63 9.3 0.8 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1129) Snapin_Pallidin PF14712.1 KND98710.1 - 4.2e-06 26.9 1.3 5.7e-06 26.5 0.9 1.2 1 0 0 1 1 1 1 Snapin/Pallidin DUF16 PF01519.11 KND98710.1 - 0.0011 19.1 1.5 1.2 9.4 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function DUF16 Seryl_tRNA_N PF02403.17 KND98710.1 - 0.0029 17.5 0.8 0.0032 17.4 0.5 1.1 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Vip3A_N PF12495.3 KND98710.1 - 0.022 14.4 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal NPV_P10 PF05531.7 KND98710.1 - 0.031 14.5 1.5 0.08 13.1 0.7 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 KND98710.1 - 0.034 13.9 1.0 0.041 13.6 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Trns_repr_metal PF02583.12 KND98710.1 - 0.058 13.5 0.6 0.12 12.5 0.4 1.6 1 1 0 1 1 1 0 Metal-sensitive transcriptional repressor DUF4349 PF14257.1 KND98710.1 - 0.07 12.3 0.4 0.075 12.2 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF2730 PF10805.3 KND98710.1 - 0.096 12.4 1.2 0.26 11.0 0.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) Prominin PF05478.6 KND98710.1 - 0.1 10.1 0.3 0.1 10.1 0.2 1.1 1 0 0 1 1 1 0 Prominin KCNQ_channel PF03520.9 KND98710.1 - 0.12 11.6 2.1 0.15 11.4 1.4 1.1 1 0 0 1 1 1 0 KCNQ voltage-gated potassium channel COG2 PF06148.6 KND98710.1 - 0.2 11.4 2.3 0.9 9.4 1.6 1.8 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Matrilin_ccoil PF10393.4 KND98710.1 - 0.55 9.6 2.5 5.2 6.5 0.9 2.1 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF676 PF05057.9 KND98711.1 - 2.2e-51 174.2 0.0 4e-51 173.3 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 KND98711.1 - 6.8e-05 22.5 0.0 0.00015 21.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 KND98711.1 - 0.0045 16.6 0.0 0.0098 15.5 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.10 KND98711.1 - 0.012 14.6 0.1 0.023 13.6 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase RNA_pol_Rpb4 PF03874.11 KND98712.1 - 2.4e-25 88.8 0.5 3e-25 88.4 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 AA_permease PF00324.16 KND98713.1 - 7.2e-83 278.5 37.2 9.1e-83 278.1 25.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND98713.1 - 3.7e-18 65.2 40.6 4.7e-18 64.9 28.1 1.1 1 0 0 1 1 1 1 Amino acid permease GCD14 PF08704.5 KND98714.1 - 3.4e-06 26.7 0.0 0.00083 18.9 0.0 2.3 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 KND98714.1 - 0.0075 15.8 0.0 0.035 13.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND98714.1 - 0.031 14.8 0.1 0.1 13.2 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain DEAD PF00270.24 KND98716.1 - 1.6e-44 151.4 0.5 3.6e-44 150.2 0.0 1.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND98716.1 - 1.5e-20 72.8 0.0 3e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KND98716.1 - 9e-20 69.9 0.2 2e-19 68.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_22 PF13401.1 KND98716.1 - 0.06 13.4 1.2 0.17 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain IncA PF04156.9 KND98716.1 - 0.27 10.7 7.2 1.3 8.5 3.2 2.2 2 0 0 2 2 2 0 IncA protein GLTT PF01744.15 KND98717.1 - 0.11 11.9 0.2 0.16 11.4 0.2 1.2 1 0 0 1 1 1 0 GLTT repeat (6 copies) Sec63 PF02889.11 KND98719.1 - 4.3e-139 463.1 0.8 6.5e-89 298.2 0.0 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KND98719.1 - 5.6e-53 178.9 0.8 1.6e-26 92.7 0.6 3.7 5 0 0 5 5 5 2 DEAD/DEAH box helicase ResIII PF04851.10 KND98719.1 - 2.8e-19 69.6 0.1 2e-08 34.2 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KND98719.1 - 8.3e-18 64.0 0.0 1.8e-07 30.9 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 KND98719.1 - 5.6e-07 29.7 0.5 0.1 12.7 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_19 PF13245.1 KND98719.1 - 1.9e-06 27.4 0.0 0.022 14.4 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA PF00004.24 KND98719.1 - 2.7e-05 24.3 1.6 0.1 12.7 0.0 4.1 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KND98719.1 - 0.00038 19.9 0.2 3.4 7.0 0.0 3.7 4 0 0 4 4 4 2 IstB-like ATP binding protein PhoH PF02562.11 KND98719.1 - 0.00049 19.3 0.0 0.14 11.3 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_10 PF12846.2 KND98719.1 - 0.0075 15.7 0.0 11 5.3 0.0 4.0 4 0 0 4 4 4 1 AAA-like domain Alba PF01918.16 KND98719.1 - 0.053 13.1 0.0 0.3 10.7 0.0 2.3 2 0 0 2 2 2 0 Alba PTS_IIB PF02302.12 KND98719.1 - 0.17 12.4 0.2 21 5.6 0.1 2.9 2 1 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit Zeta_toxin PF06414.7 KND98719.1 - 0.19 10.7 0.0 16 4.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF2361 PF10153.4 KND98720.1 - 5.2e-35 120.0 18.9 5.2e-35 120.0 13.1 2.0 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) YfdX PF10938.3 KND98720.1 - 0.16 11.6 9.3 0.41 10.2 3.0 2.5 2 1 1 3 3 3 0 YfdX protein RNA_pol_Rpb1_5 PF04998.12 KND98720.1 - 0.4 9.8 3.7 0.49 9.6 2.5 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 TGS PF02824.16 KND98721.1 - 2.1e-19 69.0 0.0 5e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KND98721.1 - 2.1e-17 63.1 0.1 5.1e-17 61.9 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KND98721.1 - 1.4e-13 50.3 0.0 3.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KND98721.1 - 9e-05 22.9 0.0 0.00026 21.4 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 KND98721.1 - 0.00046 20.0 0.9 0.027 14.2 0.0 2.6 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.11 KND98721.1 - 0.08 12.0 0.1 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 AIG1 family DUF619 PF04768.8 KND98721.1 - 0.097 12.0 0.0 0.2 11.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF619) Dynamitin PF04912.9 KND98722.1 - 3.4e-18 65.6 13.2 1.7e-17 63.3 8.1 2.1 1 1 1 2 2 2 1 Dynamitin Baculo_PEP_C PF04513.7 KND98722.1 - 0.0079 16.0 1.5 0.18 11.6 0.1 2.8 1 1 2 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.14 KND98722.1 - 0.039 11.8 8.3 0.052 11.4 5.0 1.9 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Ring_hydroxyl_B PF00866.13 KND98722.1 - 0.09 12.4 1.6 0.37 10.4 0.0 2.5 3 0 0 3 3 3 0 Ring hydroxylating beta subunit SlyX PF04102.7 KND98722.1 - 0.097 13.0 11.7 2 8.8 0.4 5.0 4 2 0 4 4 4 0 SlyX Sec5 PF15469.1 KND98722.1 - 0.097 12.3 7.3 0.071 12.8 0.4 2.8 2 1 0 2 2 2 0 Exocyst complex component Sec5 DUF1515 PF07439.6 KND98722.1 - 0.31 10.8 4.0 8.2 6.2 0.7 3.3 2 2 2 4 4 4 0 Protein of unknown function (DUF1515) FliD_C PF07195.7 KND98722.1 - 0.36 10.1 3.9 1.5 8.0 1.9 2.4 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Fib_alpha PF08702.5 KND98722.1 - 0.55 10.3 5.1 5.4 7.1 0.1 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Aldedh PF00171.17 KND98723.1 - 2e-108 362.7 0.0 2.4e-108 362.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.1 KND98723.1 - 0.054 13.1 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated SM-ATX PF14438.1 KND98724.1 - 0.038 13.9 0.0 0.043 13.7 0.0 1.0 1 0 0 1 1 1 0 Ataxin 2 SM domain Cas_csx3 PF09620.5 KND98726.1 - 0.015 15.1 0.1 0.041 13.6 0.0 1.7 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) DUF2702 PF10863.3 KND98730.1 - 7.6e-20 71.0 4.0 7.6e-20 71.0 2.8 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2702) DUF3245 PF11595.3 KND98730.1 - 0.021 15.1 0.1 0.021 15.1 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3245) SprA-related PF12118.3 KND98730.1 - 0.48 9.7 17.9 0.55 9.4 12.4 1.2 1 0 0 1 1 1 0 SprA-related family Ebola_NP PF05505.7 KND98730.1 - 0.58 8.1 11.0 0.71 7.8 7.7 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein Wbp11 PF09429.5 KND98734.1 - 0.013 15.5 1.9 0.013 15.5 1.3 2.1 2 0 0 2 2 2 0 WW domain binding protein 11 SPT6_acidic PF14632.1 KND98734.1 - 9.7 6.4 13.4 1.2 9.2 2.9 2.1 2 0 0 2 2 2 0 Acidic N-terminal SPT6 BLVR PF06375.6 KND98743.1 - 2.1 8.1 5.4 1.9 8.2 3.8 1.0 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) PFK PF00365.15 KND98744.1 - 3.1e-165 548.0 1.1 8.4e-122 405.5 1.2 2.2 2 0 0 2 2 2 2 Phosphofructokinase PhoH PF02562.11 KND98744.1 - 0.0037 16.5 0.0 0.0072 15.5 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein TgMIC1 PF11476.3 KND98744.1 - 0.11 12.0 1.8 0.29 10.6 0.0 2.3 2 0 0 2 2 2 0 Toxoplasma gondii micronemal protein 1 TgMIC1 GHMP_kinases_N PF00288.21 KND98745.1 - 0.12 12.5 0.2 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 GHMP kinases N terminal domain Glyco_hydro_16 PF00722.16 KND98747.1 - 1.8e-40 138.2 0.8 2.6e-40 137.6 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SMC_Nse1 PF07574.8 KND98748.1 - 1.9e-23 83.1 0.0 1.7e-19 70.2 0.0 2.1 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 KND98748.1 - 8.9e-07 28.8 7.3 1.4e-06 28.1 5.1 1.4 1 0 0 1 1 1 1 RING-like domain C1_1 PF00130.17 KND98748.1 - 0.00013 21.6 1.4 0.00024 20.7 0.9 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.1 KND98748.1 - 0.054 13.6 3.1 0.1 12.7 2.2 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Stn1_C PF12659.2 KND98748.1 - 0.072 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Telomere capping C-terminal wHTH FAM72 PF14976.1 KND98748.1 - 0.13 12.1 2.5 0.21 11.4 1.7 1.3 1 0 0 1 1 1 0 FAM72 protein zf-HC5HC2H_2 PF13832.1 KND98748.1 - 0.65 10.0 6.0 0.64 10.0 3.3 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain PHD PF00628.24 KND98748.1 - 1.1 8.9 6.2 4 7.2 4.5 1.7 1 1 1 2 2 2 0 PHD-finger SPRY PF00622.23 KND98749.1 - 6.3e-06 26.2 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 SPRY domain Med30 PF11315.3 KND98750.1 - 0.25 11.4 4.0 0.087 12.9 0.7 1.7 2 0 0 2 2 2 0 Mediator complex subunit 30 Novirhabdo_Nv PF05554.6 KND98754.1 - 0.096 12.2 0.1 0.1 12.0 0.1 1.0 1 0 0 1 1 1 0 Viral hemorrhagic septicemia virus non-virion protein DUF1406 PF07190.6 KND98755.1 - 0.00075 19.2 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1406) Fungal_trans PF04082.13 KND98756.1 - 1.2e-32 112.8 1.5 1.9e-31 108.8 1.0 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KND98756.1 - 2.4e-11 43.3 10.3 2.4e-11 43.3 7.2 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ten1 PF12658.2 KND98757.1 - 6.5e-09 35.6 0.0 7.5e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit DNA_pol_E_B PF04042.11 KND98758.1 - 7.2e-38 129.9 0.0 1e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Elong-fact-P_C PF09285.6 KND98758.1 - 0.12 11.7 0.0 0.32 10.3 0.0 1.7 1 0 0 1 1 1 0 Elongation factor P, C-terminal RNB PF00773.14 KND98760.1 - 2.2e-58 198.1 3.1 4e-58 197.2 2.1 1.4 1 0 0 1 1 1 1 RNB domain OB_RNB PF08206.6 KND98760.1 - 0.00099 18.5 0.1 0.83 9.1 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease B OB domain GTP_cyclohydroI PF01227.17 KND98761.1 - 7.1e-77 256.7 0.4 8.9e-77 256.4 0.3 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 KND98761.1 - 2.3e-05 24.2 0.0 4.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein OmpH PF03938.9 KND98761.1 - 0.072 13.0 0.7 0.38 10.6 0.5 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Amidase PF01425.16 KND98762.1 - 3.9e-102 342.3 0.0 4.7e-102 342.1 0.0 1.0 1 0 0 1 1 1 1 Amidase HnRNPA1 PF11627.3 KND98762.1 - 2.7 8.2 6.4 0.28 11.3 1.2 1.8 2 0 0 2 2 2 0 Nuclear factor hnRNPA1 tRNA-synt_1g PF09334.6 KND98763.1 - 7.1e-150 499.0 0.6 9.2e-150 498.6 0.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) MetRS-N PF09635.5 KND98763.1 - 3.3e-14 53.3 0.4 8e-14 52.0 0.3 1.7 1 0 0 1 1 1 1 MetRS-N binding domain tRNA-synt_1 PF00133.17 KND98763.1 - 5.2e-09 34.6 1.3 5.8e-05 21.2 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 KND98763.1 - 0.027 13.6 0.1 0.072 12.1 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain ATPgrasp_Ter PF15632.1 KND98763.1 - 0.074 11.7 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon DZR PF12773.2 KND98763.1 - 0.3 10.9 2.6 0.63 9.9 1.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon DUF1610 PF07754.6 KND98763.1 - 2.3 8.3 5.0 35 4.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) PS_Dcarbxylase PF02666.10 KND98765.1 - 1.3e-53 181.3 0.0 1.9e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 KND98765.1 - 4.2e-23 81.0 0.2 1.6e-13 50.2 0.2 2.5 2 0 0 2 2 2 2 C2 domain SRP54 PF00448.17 KND98766.1 - 2.7e-47 160.7 0.9 6.9e-47 159.4 0.6 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ArgK PF03308.11 KND98766.1 - 1.5e-06 27.2 0.0 4.2e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 ArgK protein CbiA PF01656.18 KND98766.1 - 1.7e-06 27.5 0.1 3.7e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP-alpha_N PF04086.8 KND98766.1 - 2.1e-06 27.3 3.0 2.9e-06 26.8 2.1 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.14 KND98766.1 - 6.1e-06 26.2 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_22 PF13401.1 KND98766.1 - 0.00055 20.0 0.1 0.0038 17.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KND98766.1 - 0.0025 16.9 0.0 0.0082 15.2 0.0 1.9 2 1 0 2 2 2 1 Zeta toxin AAA_25 PF13481.1 KND98766.1 - 0.0047 16.3 0.0 0.0099 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 KND98766.1 - 0.015 14.3 0.0 0.91 8.5 0.0 2.4 1 1 1 2 2 2 0 Anion-transporting ATPase AAA_10 PF12846.2 KND98766.1 - 0.015 14.7 0.1 0.05 13.0 0.1 2.0 2 1 0 2 2 2 0 AAA-like domain AAA_14 PF13173.1 KND98766.1 - 0.031 14.1 0.0 0.12 12.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KND98766.1 - 0.036 13.7 0.0 0.095 12.4 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2448 PF10476.4 KND98767.1 - 1 8.8 4.6 0.38 10.2 1.0 1.6 1 1 1 2 2 2 0 Protein of unknown function C-terminus (DUF2448) Arginase PF00491.16 KND98768.1 - 8.9e-35 120.3 0.0 1.1e-34 120.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family DUF530 PF04409.7 KND98769.1 - 0.13 10.3 0.1 0.19 9.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF530) WBP-1 PF11669.3 KND98770.1 - 0.22 11.6 1.0 0.25 11.4 0.7 1.1 1 0 0 1 1 1 0 WW domain-binding protein 1 HCV_core PF01542.13 KND98771.1 - 0.062 13.6 0.1 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Hepatitis C virus core protein A_deaminase PF00962.17 KND98772.1 - 1.4e-107 359.5 0.0 1.9e-107 359.0 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Phos_pyr_kin PF08543.7 KND98773.1 - 3e-65 219.8 0.2 4.6e-65 219.2 0.1 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 KND98773.1 - 1.3e-40 139.3 0.2 1.9e-40 138.8 0.2 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family HK PF02110.10 KND98773.1 - 0.0027 16.9 0.1 1.1 8.3 0.0 2.2 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family PfkB PF00294.19 KND98773.1 - 0.054 12.6 0.0 0.22 10.5 0.0 2.0 2 1 0 2 2 2 0 pfkB family carbohydrate kinase EF-hand_4 PF12763.2 KND98777.1 - 2.4e-22 78.6 0.0 8.8e-13 47.9 0.0 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.6 KND98777.1 - 4.7e-11 42.5 193.3 3.9e-06 26.8 3.8 11.9 6 4 4 10 10 10 6 Domain of unknown function (DUF1720) WH2 PF02205.15 KND98777.1 - 3e-05 23.4 0.1 9.9e-05 21.8 0.1 2.0 1 0 0 1 1 1 1 WH2 motif EF-hand_7 PF13499.1 KND98777.1 - 0.00027 21.0 0.0 0.035 14.2 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KND98777.1 - 0.00046 19.2 0.0 0.21 10.9 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KND98777.1 - 0.063 13.1 0.0 0.9 9.5 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain DUF3671 PF12420.3 KND98777.1 - 3.2 7.7 3.1 6.1 6.8 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function E3_binding PF02817.12 KND98777.1 - 7.2 6.3 9.3 0.13 11.8 0.1 2.6 3 0 0 3 3 3 0 e3 binding domain AAA_2 PF07724.9 KND98778.1 - 1.7e-50 171.2 0.0 1.7e-50 171.2 0.0 3.1 4 0 0 4 4 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 KND98778.1 - 6.9e-26 89.9 0.5 3.3e-25 87.8 0.1 2.5 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 KND98778.1 - 1.9e-20 73.4 0.3 2.1e-10 40.9 0.1 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KND98778.1 - 1.5e-16 60.3 2.1 4.3e-11 42.7 0.0 3.5 3 1 1 4 4 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KND98778.1 - 5.1e-15 55.9 3.5 6.2e-05 23.0 0.0 4.5 3 2 2 5 5 4 3 AAA ATPase domain AAA_22 PF13401.1 KND98778.1 - 8.6e-11 42.1 0.8 0.00012 22.2 0.1 4.0 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 KND98778.1 - 6.4e-08 32.2 0.1 2.8e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 KND98778.1 - 1.8e-07 31.1 3.7 0.021 14.6 0.0 3.7 3 1 0 3 3 3 2 AAA domain Arch_ATPase PF01637.13 KND98778.1 - 1.5e-06 28.1 14.2 0.15 11.6 0.1 5.2 3 2 1 4 4 4 3 Archaeal ATPase AAA_28 PF13521.1 KND98778.1 - 8.1e-06 25.8 2.3 0.57 10.1 0.0 4.0 4 1 0 4 4 3 2 AAA domain IstB_IS21 PF01695.12 KND98778.1 - 3.1e-05 23.4 0.1 0.31 10.4 0.0 3.0 3 0 0 3 3 3 2 IstB-like ATP binding protein NACHT PF05729.7 KND98778.1 - 3.2e-05 23.6 0.2 0.083 12.5 0.0 3.0 3 0 0 3 3 3 2 NACHT domain RNA_helicase PF00910.17 KND98778.1 - 3.6e-05 23.8 0.4 0.31 11.2 0.0 3.3 3 1 0 3 3 3 2 RNA helicase TrwB_AAD_bind PF10412.4 KND98778.1 - 4e-05 22.4 0.3 0.17 10.4 0.1 2.7 2 1 1 3 3 3 2 Type IV secretion-system coupling protein DNA-binding domain OmpH PF03938.9 KND98778.1 - 4.2e-05 23.5 0.0 0.00053 19.9 0.0 2.4 1 1 0 1 1 1 1 Outer membrane protein (OmpH-like) AAA_30 PF13604.1 KND98778.1 - 7e-05 22.4 0.6 0.24 10.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KND98778.1 - 7.1e-05 23.6 7.7 0.016 16.0 0.1 4.1 2 2 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KND98778.1 - 7.3e-05 22.4 0.0 0.2 11.4 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain MMR_HSR1 PF01926.18 KND98778.1 - 0.00011 22.1 0.1 0.0062 16.4 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 KND98778.1 - 0.00011 21.3 0.0 0.0045 16.1 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin PhoH PF02562.11 KND98778.1 - 0.00015 21.0 0.1 0.12 11.5 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein MobB PF03205.9 KND98778.1 - 0.00017 21.3 0.0 0.16 11.6 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 KND98778.1 - 0.00033 19.6 2.2 0.1 11.4 0.3 3.7 2 2 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 KND98778.1 - 0.00092 18.4 0.1 1.2 8.2 0.0 3.2 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI SRP54 PF00448.17 KND98778.1 - 0.0018 17.7 0.1 0.35 10.2 0.0 3.1 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 KND98778.1 - 0.0034 16.8 0.1 0.52 9.7 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 KND98778.1 - 0.0046 16.5 0.0 3.2 7.4 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF2075 PF09848.4 KND98778.1 - 0.0054 15.7 2.4 0.013 14.4 0.0 2.6 3 1 0 3 3 2 1 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.12 KND98778.1 - 0.0062 16.3 7.8 0.87 9.3 0.0 4.1 3 1 1 4 4 3 1 Domain of unknown function DUF87 Torsin PF06309.6 KND98778.1 - 0.0067 16.3 0.0 0.06 13.2 0.0 2.3 2 0 0 2 2 2 1 Torsin T2SE PF00437.15 KND98778.1 - 0.0077 15.1 2.4 0.41 9.4 0.4 2.7 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.1 KND98778.1 - 0.0079 15.6 0.8 2.9 7.2 0.1 3.1 2 2 0 2 2 2 1 AAA domain Myosin_tail_1 PF01576.14 KND98778.1 - 0.0087 13.8 17.8 0.013 13.2 12.3 1.1 1 0 0 1 1 1 1 Myosin tail AAA_18 PF13238.1 KND98778.1 - 0.0091 16.2 11.4 0.23 11.7 0.2 3.8 3 1 1 4 4 2 2 AAA domain DUF853 PF05872.7 KND98778.1 - 0.012 13.9 5.9 0.021 13.1 0.1 3.0 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF853) ABC_tran PF00005.22 KND98778.1 - 0.014 15.7 6.2 0.71 10.1 0.0 3.8 3 1 0 3 3 3 0 ABC transporter AAA_33 PF13671.1 KND98778.1 - 0.026 14.3 0.0 1.7 8.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain Malic_M PF03949.10 KND98778.1 - 0.085 12.3 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain ResIII PF04851.10 KND98778.1 - 0.089 12.6 10.7 2.4 7.9 0.3 4.0 4 1 1 5 5 4 0 Type III restriction enzyme, res subunit AAA_29 PF13555.1 KND98778.1 - 0.12 11.8 0.1 4.3 6.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Miro PF08477.8 KND98778.1 - 0.18 12.3 3.6 2.2 8.7 0.1 3.1 3 0 0 3 3 2 0 Miro-like protein AAA_10 PF12846.2 KND98778.1 - 0.55 9.6 3.6 3.4 6.9 0.0 3.0 3 2 0 3 3 2 0 AAA-like domain AAA_15 PF13175.1 KND98778.1 - 0.58 9.1 8.0 0.31 10.0 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.1 KND98778.1 - 0.61 8.4 11.2 0.67 8.3 6.8 1.8 2 0 0 2 2 2 0 AAA domain V_ATPase_I PF01496.14 KND98778.1 - 0.99 7.1 8.7 1.5 6.5 6.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UvrD-helicase PF00580.16 KND98778.1 - 2.7 7.1 12.4 1.2 8.3 0.0 2.8 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain TPR_MLP1_2 PF07926.7 KND98778.1 - 5.9 6.6 21.3 1.6 8.5 10.1 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 KND98778.1 - 7 5.6 14.4 14 4.6 10.0 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 KND98778.1 - 7.6 6.6 18.4 0.87 9.6 8.0 3.1 3 1 1 4 4 2 0 Seryl-tRNA synthetase N-terminal domain Sec20 PF03908.8 KND98779.1 - 0.23 11.1 1.9 0.5 10.1 0.0 2.5 2 1 1 3 3 3 0 Sec20 RR_TM4-6 PF06459.7 KND98779.1 - 3.1 7.5 21.7 2.9 7.7 7.5 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CAF-1_p150 PF11600.3 KND98779.1 - 8 5.7 41.4 4.1 6.7 12.4 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Metallothi_Euk2 PF12809.2 KND98781.1 - 0.06 13.7 7.3 0.14 12.5 5.1 1.6 1 0 0 1 1 1 0 Eukaryotic metallothionein PalH PF08733.5 KND98782.1 - 7.9e-66 222.2 18.7 1.1e-65 221.8 12.9 1.1 1 0 0 1 1 1 1 PalH/RIM21 DUF373 PF04123.8 KND98782.1 - 9.4 5.1 14.8 0.93 8.4 6.0 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF373) PsbM PF05151.7 KND98784.1 - 0.034 13.7 0.1 0.053 13.1 0.1 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) UNC45-central PF11701.3 KND98785.1 - 1.3e-13 50.9 3.9 1.1e-12 47.8 0.0 3.7 2 1 0 2 2 2 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 KND98785.1 - 0.00011 22.4 0.8 2.5 8.4 0.0 4.7 3 2 1 4 4 4 2 HEAT repeats Arm PF00514.18 KND98785.1 - 0.0046 16.7 11.7 0.045 13.5 0.0 6.1 7 1 0 7 7 7 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KND98785.1 - 0.15 12.2 3.4 24 5.3 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat Sec23_trunk PF04811.10 KND98786.1 - 2.6e-45 154.7 0.0 4.9e-45 153.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KND98786.1 - 3.5e-20 71.3 0.6 7.3e-20 70.3 0.4 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KND98786.1 - 1.8e-15 57.1 0.0 3.8e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KND98786.1 - 5.3e-12 45.0 8.0 1e-11 44.1 5.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Serglycin PF04360.7 KND98787.1 - 0.25 11.0 1.4 0.28 10.9 0.9 1.2 1 0 0 1 1 1 0 Serglycin Mgr1 PF08602.5 KND98790.1 - 1.6e-27 96.4 5.0 3.1e-13 49.4 1.0 3.3 1 1 2 3 3 3 3 Mgr1-like, i-AAA protease complex subunit COX5A PF02284.11 KND98793.1 - 0.49 10.3 3.0 0.49 10.3 0.2 2.0 2 1 0 2 2 2 0 Cytochrome c oxidase subunit Va bZIP_1 PF00170.16 KND98795.1 - 1.2e-07 31.5 18.1 2.1e-05 24.3 12.5 2.2 1 1 0 1 1 1 1 bZIP transcription factor Phage_GP20 PF06810.6 KND98795.1 - 0.0044 16.4 1.6 0.0062 15.9 1.1 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 CCDC92 PF14916.1 KND98795.1 - 0.03 13.8 1.1 0.069 12.7 0.7 1.6 1 0 0 1 1 1 0 Coiled-coil domain of unknown function HAUS6_N PF14661.1 KND98795.1 - 0.036 13.4 5.1 0.052 12.9 3.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus V_ATPase_I PF01496.14 KND98795.1 - 0.064 11.1 4.1 0.081 10.7 2.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Glutaredoxin2_C PF04399.8 KND98795.1 - 0.066 12.7 0.7 0.1 12.2 0.5 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain IncA PF04156.9 KND98795.1 - 0.074 12.6 0.9 0.097 12.2 0.6 1.2 1 0 0 1 1 1 0 IncA protein Fzo_mitofusin PF04799.8 KND98795.1 - 0.098 12.0 3.4 0.14 11.5 2.4 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF904 PF06005.7 KND98795.1 - 0.1 12.9 8.0 0.073 13.3 4.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF904) NYD-SP28_assoc PF14775.1 KND98795.1 - 0.15 11.7 3.5 0.31 10.7 2.4 1.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain EABR PF12180.3 KND98795.1 - 0.2 11.0 3.1 0.56 9.6 2.1 1.8 1 1 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 DivIC PF04977.10 KND98795.1 - 0.24 10.9 4.6 0.088 12.3 1.0 1.8 1 1 1 2 2 2 0 Septum formation initiator DUF2730 PF10805.3 KND98795.1 - 0.29 10.8 2.6 0.43 10.3 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) bZIP_2 PF07716.10 KND98795.1 - 0.61 9.9 17.2 0.45 10.3 1.4 2.2 1 1 1 2 2 2 0 Basic region leucine zipper PAT1 PF09770.4 KND98795.1 - 0.61 8.2 13.7 0.71 8.0 9.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 KND98795.1 - 0.88 8.9 14.9 0.98 8.7 10.3 1.1 1 0 0 1 1 1 0 Vta1 like APG6 PF04111.7 KND98795.1 - 2.3 7.1 7.1 2.8 6.9 4.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 AvrPto PF11592.3 KND98796.1 - 0.05 13.3 0.0 0.051 13.3 0.0 1.0 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto DUF865 PF05906.6 KND98798.1 - 0.043 13.4 0.1 0.098 12.2 0.1 1.6 1 0 0 1 1 1 0 Herpesvirus-7 repeat of unknown function (DUF865) PBP PF01161.15 KND98801.1 - 3.4e-08 33.4 0.1 6.3e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein MIF4G PF02854.14 KND98803.1 - 6.5e-16 58.3 27.1 2.9e-08 33.3 0.0 4.5 4 1 0 5 5 5 3 MIF4G domain Upf2 PF04050.9 KND98803.1 - 1.8e-06 27.8 13.6 1.8e-06 27.8 9.4 2.7 1 1 1 2 2 2 1 Up-frameshift suppressor 2 Astro_capsid PF03115.9 KND98803.1 - 0.36 9.0 9.4 0.73 8.0 6.5 1.4 1 0 0 1 1 1 0 Astrovirus capsid protein precursor SpoIIE PF07228.7 KND98804.1 - 6.8e-25 87.9 0.0 9.9e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 KND98804.1 - 4e-08 32.9 1.8 0.00025 20.5 0.0 2.4 2 1 1 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.1 KND98804.1 - 4.8e-07 29.4 0.1 9.5e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C ATP-synt_E PF05680.7 KND98805.1 - 2.8e-21 75.2 0.3 2.9e-21 75.1 0.2 1.0 1 0 0 1 1 1 1 ATP synthase E chain FYVE PF01363.16 KND98806.1 - 1.1e-18 66.8 15.2 4.5e-15 55.3 0.5 3.0 3 0 0 3 3 3 2 FYVE zinc finger zf-AN1 PF01428.11 KND98806.1 - 0.001 18.8 3.9 0.001 18.8 2.7 3.0 3 0 0 3 3 3 1 AN1-like Zinc finger zf-Di19 PF05605.7 KND98806.1 - 0.0014 18.7 3.6 0.0024 17.9 0.2 2.6 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Rbsn PF11464.3 KND98806.1 - 0.0024 17.4 0.1 0.0077 15.7 0.1 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain HARE-HTH PF05066.8 KND98807.1 - 0.041 14.2 0.0 0.047 14.0 0.0 1.1 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain Sugar_tr PF00083.19 KND98808.1 - 2.1e-107 359.5 23.8 2.9e-107 359.0 16.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND98808.1 - 9.1e-20 70.6 21.7 9.1e-20 70.6 15.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily CDC45 PF02724.9 KND98810.1 - 3.8e-202 672.6 0.5 5.2e-202 672.2 0.3 1.2 1 0 0 1 1 1 1 CDC45-like protein DUF2415 PF10313.4 KND98811.1 - 2.7e-17 62.1 0.9 6.2e-17 61.0 0.6 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Cation_efflux PF01545.16 KND98814.1 - 3.1e-75 252.9 0.1 3.8e-75 252.5 0.1 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 KND98814.1 - 0.005 15.8 0.1 0.0081 15.2 0.1 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter B12-binding_2 PF02607.12 KND98815.1 - 0.038 14.0 0.1 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain Opi1 PF08618.5 KND98817.1 - 2.8e-19 69.3 15.9 4.9e-10 38.9 0.3 4.0 2 1 2 4 4 4 3 Transcription factor Opi1 DUF1993 PF09351.5 KND98817.1 - 0.07 13.0 2.8 0.49 10.3 0.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1993) WW PF00397.21 KND98818.1 - 2.5e-08 33.6 1.5 4.3e-08 32.8 1.0 1.4 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.4 KND98818.1 - 0.0033 17.5 15.9 0.0033 17.5 11.0 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) ETC_C1_NDUFA5 PF04716.9 KND98820.1 - 1.6e-24 85.2 0.2 3.3e-24 84.1 0.1 1.6 1 0 0 1 1 1 1 ETC complex I subunit conserved region Ras PF00071.17 KND98821.1 - 7.6e-64 213.9 0.1 9e-64 213.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KND98821.1 - 3.7e-19 69.3 0.0 7.2e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KND98821.1 - 1e-15 57.3 0.0 1.3e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KND98821.1 - 1.3e-07 31.0 0.0 1.5e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KND98821.1 - 4.6e-07 29.4 0.1 1.7e-06 27.5 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KND98821.1 - 5.1e-05 23.1 0.2 0.00027 20.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 KND98821.1 - 0.00011 21.4 0.0 0.00015 21.0 0.0 1.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KND98821.1 - 0.00057 19.2 0.0 0.002 17.4 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.1 KND98821.1 - 0.0064 16.4 0.2 0.029 14.3 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KND98821.1 - 0.007 16.5 0.0 0.043 13.9 0.0 2.1 1 1 1 2 2 2 1 AAA domain G-alpha PF00503.15 KND98821.1 - 0.0099 14.6 1.4 1.2 7.7 0.0 2.8 1 1 1 2 2 2 1 G-protein alpha subunit DUF258 PF03193.11 KND98821.1 - 0.02 14.0 0.0 0.061 12.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 KND98821.1 - 0.022 14.2 0.2 0.064 12.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Septin PF00735.13 KND98821.1 - 0.025 13.6 0.0 0.062 12.3 0.0 1.6 1 0 0 1 1 1 0 Septin B3_4 PF03483.12 KND98822.1 - 7.6e-27 93.8 0.0 1.4e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KND98822.1 - 9.4e-20 70.2 0.0 4.4e-15 55.2 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain YPEB PF14620.1 KND98822.1 - 0.17 10.8 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 YpeB sporulation DUF726 PF05277.7 KND98823.1 - 1.2e-132 442.0 0.5 1.7e-132 441.5 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF3115 PF11312.3 KND98824.1 - 6.7e-94 314.2 0.1 8.3e-94 313.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) SIR2 PF02146.12 KND98825.1 - 1.6e-56 190.8 0.0 2.7e-56 190.0 0.0 1.4 1 0 0 1 1 1 1 Sir2 family Cytochrome_C7 PF14522.1 KND98825.1 - 0.05 13.2 1.1 0.13 11.8 0.7 1.7 1 0 0 1 1 1 0 Cytochrome c7 zf-dskA_traR PF01258.12 KND98825.1 - 0.36 10.5 0.1 0.36 10.5 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Paired_CXXCH_1 PF09699.5 KND98825.1 - 0.37 10.3 4.5 0.83 9.2 3.1 1.6 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) DUF3441 PF11923.3 KND98826.1 - 9.8e-32 108.8 2.0 1.5e-31 108.2 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 KND98826.1 - 2.1e-11 43.5 0.0 8.5e-11 41.5 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF814) ADH_N PF08240.7 KND98827.1 - 7.4e-27 93.2 0.1 1.3e-26 92.4 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KND98827.1 - 5.4e-21 74.5 0.0 1.1e-20 73.5 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KND98827.1 - 3.3e-13 50.6 0.0 5.8e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KND98827.1 - 3.1e-05 23.5 0.0 4.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 KND98827.1 - 0.081 12.5 0.0 0.38 10.3 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KND98827.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 KND98827.1 - 0.13 12.8 0.0 0.4 11.2 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain GST_C PF00043.20 KND98828.1 - 1.1e-18 67.0 0.0 1.7e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KND98828.1 - 8.7e-15 54.6 0.0 1.8e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KND98828.1 - 9.5e-10 38.3 0.0 1.9e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KND98828.1 - 1.6e-09 37.8 0.0 3.3e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KND98828.1 - 0.007 16.2 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RD3 PF14473.1 KND98829.1 - 0.17 11.3 1.6 0.17 11.3 1.1 1.1 1 0 0 1 1 1 0 RD3 protein NST1 PF13945.1 KND98829.1 - 0.2 11.6 4.6 0.19 11.8 3.2 1.0 1 0 0 1 1 1 0 Salt tolerance down-regulator ATP-synt_E PF05680.7 KND98829.1 - 0.24 11.3 3.1 0.24 11.3 2.2 1.1 1 0 0 1 1 1 0 ATP synthase E chain GATase PF00117.23 KND98830.1 - 2.3e-06 27.2 0.0 7.5e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KND98830.1 - 0.066 12.6 0.0 0.13 11.7 0.0 1.6 1 1 0 1 1 1 0 Peptidase C26 Cyt-b5 PF00173.23 KND98834.1 - 2.6e-11 43.1 0.0 3.7e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RRM_1 PF00076.17 KND98835.1 - 2e-17 62.5 0.0 3.8e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 KND98835.1 - 2.2e-15 56.7 5.7 4.7e-15 55.6 3.9 1.6 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_6 PF14259.1 KND98835.1 - 7.4e-13 48.2 0.0 1.2e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND98835.1 - 3.6e-05 23.5 0.0 6.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YABBY PF04690.8 KND98835.1 - 0.22 11.7 1.2 0.59 10.3 0.8 1.7 1 0 0 1 1 1 0 YABBY protein Kri1_C PF12936.2 KND98839.1 - 4.6e-30 103.4 4.9 4.6e-30 103.4 3.4 4.5 3 2 1 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.7 KND98839.1 - 5.9e-22 77.8 16.6 5.9e-22 77.8 11.5 6.2 4 2 1 5 5 5 1 KRI1-like family CorA PF01544.13 KND98840.1 - 1.4e-41 142.4 0.0 2.6e-27 95.6 0.0 2.5 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Coprogen_oxidas PF01218.13 KND98843.1 - 1.3e-130 434.2 0.1 1.5e-130 434.0 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase XLF PF09302.6 KND98844.1 - 4.6e-06 26.5 0.0 1.6e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 XLF (XRCC4-like factor) HOOK PF05622.7 KND98844.1 - 0.048 11.4 0.1 0.064 11.0 0.1 1.2 1 0 0 1 1 1 0 HOOK protein DUF4463 PF14703.1 KND98844.1 - 1.5 9.3 4.6 22 5.6 0.1 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4463) AAA_33 PF13671.1 KND98845.1 - 1.2e-05 25.2 0.2 0.00023 21.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KND98845.1 - 3.3e-05 23.9 0.1 6.6e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain PRK PF00485.13 KND98845.1 - 3.8e-05 23.3 0.0 5.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family ArgK PF03308.11 KND98845.1 - 4.9e-05 22.2 0.0 9.2e-05 21.3 0.0 1.4 2 0 0 2 2 2 1 ArgK protein AAA_17 PF13207.1 KND98845.1 - 7.4e-05 23.5 0.0 0.00016 22.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KND98845.1 - 0.00018 20.6 0.1 0.00054 19.1 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin KTI12 PF08433.5 KND98845.1 - 0.00068 18.9 0.0 0.0017 17.6 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 KND98845.1 - 0.00075 19.8 0.0 0.003 17.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KND98845.1 - 0.0016 18.0 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 KND98845.1 - 0.0016 18.1 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 NTPase AAA_19 PF13245.1 KND98845.1 - 0.0017 18.0 0.1 0.0044 16.7 0.0 1.7 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 KND98845.1 - 0.0073 15.8 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.12 KND98845.1 - 0.0075 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 KND98845.1 - 0.012 15.0 0.0 0.046 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain NACHT PF05729.7 KND98845.1 - 0.014 15.0 0.1 0.059 13.0 0.0 1.9 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 KND98845.1 - 0.022 14.1 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 KND98845.1 - 0.025 14.0 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KND98845.1 - 0.032 14.3 0.0 0.1 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 KND98845.1 - 0.039 13.6 0.1 0.084 12.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 KND98845.1 - 0.049 12.8 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KND98845.1 - 0.058 13.3 0.0 0.094 12.6 0.0 1.6 2 0 0 2 2 1 0 50S ribosome-binding GTPase SRP54 PF00448.17 KND98845.1 - 0.069 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 KND98845.1 - 0.085 13.1 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter T2SE PF00437.15 KND98845.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Miro PF08477.8 KND98845.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein PIN_4 PF13638.1 KND98846.1 - 5.3e-32 110.7 1.2 1.4e-31 109.3 0.2 2.1 3 0 0 3 3 3 1 PIN domain DUF155 PF02582.9 KND98847.1 - 5.4e-57 192.4 0.2 1e-56 191.5 0.2 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 tRNA-synt_1c PF00749.16 KND98848.1 - 4.1e-113 377.2 0.0 5.6e-113 376.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KND98848.1 - 1e-40 139.2 3.7 2.5e-40 137.9 2.5 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 KND98848.1 - 3.7e-09 36.9 0.0 1.4e-08 35.1 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KND98848.1 - 3e-05 23.9 0.1 8.7e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KND98848.1 - 3.9e-05 23.4 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NADHdh PF00146.16 KND98849.1 - 4.4e-26 91.6 2.7 4.9e-26 91.5 1.9 1.0 1 0 0 1 1 1 1 NADH dehydrogenase COX1 PF00115.15 KND98851.1 - 2.1e-19 69.4 5.0 2.3e-19 69.3 3.5 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I NdhL PF10716.4 KND98851.1 - 0.079 12.7 0.3 0.083 12.6 0.2 1.2 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit CTD_bind PF04818.8 KND98852.1 - 9.2e-22 77.0 0.0 3.1e-21 75.3 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase II-binding domain. APC_CDC26 PF10471.4 KND98852.1 - 0.28 11.9 0.2 0.28 11.9 0.1 3.2 3 1 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 Myc_N PF01056.13 KND98852.1 - 0.3 10.2 12.6 0.66 9.0 8.7 1.6 1 1 0 1 1 1 0 Myc amino-terminal region DUF4164 PF13747.1 KND98852.1 - 0.31 11.1 5.3 0.75 9.9 3.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Zn_clus PF00172.13 KND98853.1 - 1.6e-05 24.6 16.4 2.9e-05 23.8 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 KND98853.1 - 0.026 14.6 6.9 0.056 13.6 4.8 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region UvrD-helicase PF00580.16 KND98854.1 - 1.2e-33 116.7 0.0 9.6e-30 103.9 0.0 3.6 2 2 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 KND98854.1 - 4.9e-28 98.5 0.0 4.3e-27 95.5 0.0 2.6 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.1 KND98854.1 - 1.5e-11 44.3 0.0 3.9e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 KND98854.1 - 1.8e-11 43.5 0.0 8.5e-11 41.4 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_11 PF13086.1 KND98854.1 - 8.4e-06 25.5 0.0 5.9e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KND98854.1 - 0.00042 19.9 0.0 0.022 14.2 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KND98854.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain MukB PF04310.7 KND98854.1 - 0.0047 16.2 0.0 0.25 10.6 0.0 2.2 1 1 1 2 2 2 1 MukB N-terminal AAA_12 PF13087.1 KND98854.1 - 0.009 15.3 0.0 3.1 7.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain PAZ PF02170.17 KND98854.1 - 0.011 15.0 0.1 0.024 13.9 0.1 1.5 1 0 0 1 1 1 0 PAZ domain DEAD PF00270.24 KND98854.1 - 0.057 12.9 0.1 0.34 10.3 0.1 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase Vps52 PF04129.7 KND98855.1 - 4e-73 246.6 4.8 2.8e-49 168.0 0.5 2.0 2 0 0 2 2 2 2 Vps52 / Sac2 family Rep_fac_C PF08542.6 KND98856.1 - 2.5e-19 69.0 0.1 5.4e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 KND98856.1 - 4.8e-11 42.9 0.0 8.2e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KND98856.1 - 1.7e-10 40.8 0.1 8.4e-09 35.2 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 KND98856.1 - 3.4e-07 30.1 0.0 5.9e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KND98856.1 - 6.2e-07 29.0 0.0 9.9e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KND98856.1 - 7e-06 25.2 0.0 2.8e-05 23.2 0.0 1.9 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KND98856.1 - 7.3e-06 26.0 0.0 0.00053 20.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KND98856.1 - 9.4e-06 25.7 0.1 0.063 13.4 0.0 2.5 1 1 1 2 2 2 2 AAA domain Rad17 PF03215.10 KND98856.1 - 1.6e-05 23.8 0.0 0.0023 16.7 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 KND98856.1 - 0.00064 19.2 0.0 0.12 11.8 0.0 2.4 1 1 0 2 2 2 1 AAA-like domain FtsK_SpoIIIE PF01580.13 KND98856.1 - 0.0007 19.1 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Viral_helicase1 PF01443.13 KND98856.1 - 0.0012 18.4 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.16 KND98856.1 - 0.0016 17.6 0.0 0.018 14.2 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KND98856.1 - 0.0097 15.3 0.0 3.1 7.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KND98856.1 - 0.019 14.6 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain ArgK PF03308.11 KND98856.1 - 0.042 12.6 0.0 0.95 8.1 0.0 2.3 1 1 1 2 2 2 0 ArgK protein AAA_33 PF13671.1 KND98856.1 - 0.045 13.6 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KND98856.1 - 0.064 12.9 0.0 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 NTPase DNA_pol3_delta PF06144.8 KND98856.1 - 0.067 12.7 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_5 PF07728.9 KND98856.1 - 0.14 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNase_P_pop3 PF08228.6 KND98857.1 - 2.4e-14 53.4 0.0 4.2e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 RNase P subunit Pop3 RNA_pol_Rpb1_5 PF04998.12 KND98858.1 - 1.2e-108 362.6 0.1 1.8e-108 362.0 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 KND98858.1 - 3e-105 352.1 0.0 5e-105 351.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 KND98858.1 - 9.1e-71 237.1 0.0 2.2e-70 235.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 KND98858.1 - 4.8e-68 228.5 2.2 1.5e-67 226.9 0.1 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 KND98858.1 - 2e-50 170.5 0.0 4.3e-50 169.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 KND98858.1 - 5.7e-48 162.0 2.6 1.5e-47 160.7 1.8 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 KND98858.1 - 9.1e-38 128.3 0.1 2.4e-37 126.9 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 KND98858.1 - 1.1e-23 81.2 335.6 0.0095 15.9 6.6 18.1 7 1 7 21 21 21 19 RNA polymerase Rpb1 C-terminal repeat Alpha-amylase PF00128.19 KND98859.1 - 7.4e-106 354.1 2.1 1.3e-105 353.2 1.5 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KND98859.1 - 0.00019 20.4 0.9 0.0022 16.9 0.0 2.5 3 0 0 3 3 3 1 glucanotransferase domain of human glycogen debranching enzyme Na_Ca_ex PF01699.19 KND98860.1 - 7.4e-29 100.1 23.7 3.7e-16 59.0 7.3 4.3 4 1 1 5 5 5 2 Sodium/calcium exchanger protein DUF307 PF03733.8 KND98860.1 - 2.7e-16 59.7 4.4 2.7e-16 59.7 3.1 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF307) DUF3295 PF11702.3 KND98860.1 - 0.12 11.3 8.6 0.017 14.1 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) Phage_tube PF04985.9 KND98860.1 - 0.36 10.2 0.9 0.56 9.6 0.0 1.7 2 0 0 2 2 2 0 Phage tail tube protein FII DUF1049 PF06305.6 KND98860.1 - 3.5 7.1 7.8 6.4 6.3 1.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) DER1 PF04511.10 KND98861.1 - 9.3e-26 90.5 15.8 2.4e-21 76.1 9.0 2.1 2 0 0 2 2 2 2 Der1-like family LSM PF01423.17 KND98862.1 - 2.8e-11 42.7 0.0 4e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KND98862.1 - 0.046 13.6 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF2031 PF09592.5 KND98863.1 - 0.38 9.8 2.9 0.49 9.5 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) ATP-synt_DE_N PF02823.11 KND98864.1 - 3.7e-19 68.2 0.0 6.3e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain HisKA_2 PF07568.7 KND98864.1 - 0.047 13.5 0.2 2.5 8.0 0.0 2.3 2 0 0 2 2 2 0 Histidine kinase Med2 PF11214.3 KND98865.1 - 1.1e-34 118.5 0.8 1.1e-34 118.5 0.5 3.9 1 1 1 2 2 1 1 Mediator complex subunit 2 MIP-T3 PF10243.4 KND98865.1 - 1.1e-05 24.0 28.2 1.2e-05 24.0 19.5 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Fmp27_WPPW PF10359.4 KND98865.1 - 0.013 13.9 16.9 0.016 13.6 11.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Spore_coat_CotO PF14153.1 KND98865.1 - 0.029 13.8 27.3 0.04 13.3 18.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO SPX PF03105.14 KND98865.1 - 0.049 13.4 16.6 0.059 13.1 11.5 1.1 1 0 0 1 1 1 0 SPX domain Hid1 PF12722.2 KND98865.1 - 0.12 10.0 11.8 0.12 10.0 8.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF765 PF05570.6 KND98865.1 - 0.16 11.9 0.2 0.28 11.1 0.2 1.3 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF765) MAP7 PF05672.6 KND98865.1 - 0.2 11.0 65.5 0.32 10.3 45.4 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Daxx PF03344.10 KND98865.1 - 0.41 9.0 28.7 0.49 8.8 19.9 1.1 1 0 0 1 1 1 0 Daxx Family SAPS PF04499.10 KND98865.1 - 0.75 8.3 14.6 0.87 8.1 10.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PLRV_ORF5 PF01690.12 KND98865.1 - 0.95 8.5 14.3 1.1 8.2 9.9 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SprA-related PF12118.3 KND98865.1 - 1.5 8.1 23.2 1.9 7.7 16.1 1.2 1 0 0 1 1 1 0 SprA-related family Asp-B-Hydro_N PF05279.6 KND98865.1 - 1.9 8.2 33.6 2.9 7.6 23.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MMR1 PF08505.5 KND98865.1 - 2.2 8.2 15.5 3.9 7.4 10.7 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Exonuc_VII_L PF02601.10 KND98865.1 - 3 6.9 14.1 4.1 6.5 9.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Neur_chan_memb PF02932.11 KND98865.1 - 3.7 7.3 8.8 5.1 6.9 6.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2201_N PF13203.1 KND98865.1 - 6.5 5.8 15.3 8.5 5.4 10.6 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Dsh_C PF12316.3 KND98865.1 - 8.9 6.3 6.4 13 5.8 4.4 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Cwf_Cwc_15 PF04889.7 KND98865.1 - 9.6 5.8 40.6 14 5.3 28.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Rad21_Rec8_N PF04825.8 KND98867.1 - 9.9e-30 102.7 0.0 2.3e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KND98867.1 - 6.2e-07 28.5 0.0 1.6e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein WD40 PF00400.27 KND98868.1 - 2.6 8.0 8.7 17 5.4 0.1 4.3 4 1 0 4 4 4 0 WD domain, G-beta repeat Sld5 PF05916.6 KND98869.1 - 8.9e-10 38.8 0.6 2.3e-09 37.5 0.4 1.7 1 0 0 1 1 1 1 GINS complex protein CCDC142 PF14923.1 KND98869.1 - 0.017 13.4 0.8 0.2 9.9 0.0 2.0 2 0 0 2 2 2 0 Coiled-coil protein 142 DUF2577 PF10844.3 KND98869.1 - 0.11 12.5 0.8 0.45 10.5 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2577) WD40 PF00400.27 KND98870.1 - 8.6e-20 69.8 6.2 1.1e-07 31.4 0.0 5.9 7 0 0 7 7 7 4 WD domain, G-beta repeat zf-RING_2 PF13639.1 KND98870.1 - 2.9e-05 23.8 5.6 2.9e-05 23.8 3.9 2.3 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KND98870.1 - 0.0039 17.1 6.6 0.0039 17.1 4.6 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KND98870.1 - 0.037 14.1 12.7 0.089 12.9 8.8 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger DUF1168 PF06658.7 KND98871.1 - 0.12 11.9 3.5 0.1 12.1 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) BLVR PF06375.6 KND98871.1 - 0.18 11.6 3.8 0.16 11.7 2.6 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) SART-1 PF03343.8 KND98871.1 - 2.7 6.2 7.4 2.8 6.1 5.2 1.0 1 0 0 1 1 1 0 SART-1 family Abhydrolase_5 PF12695.2 KND98872.1 - 7.7e-20 71.1 0.0 1.4e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND98872.1 - 1.8e-15 57.4 0.0 1.3e-13 51.3 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND98872.1 - 6.2e-08 32.4 0.0 0.0017 17.9 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KND98872.1 - 0.00014 21.3 0.2 0.23 10.8 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KND98872.1 - 0.00063 19.0 0.1 0.0047 16.1 0.1 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 KND98872.1 - 0.00075 18.0 0.1 0.48 8.8 0.0 2.6 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.3 KND98872.1 - 0.0017 18.1 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF818 PF05677.7 KND98872.1 - 0.002 16.9 0.1 0.0032 16.2 0.1 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.8 KND98872.1 - 0.024 14.0 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) BAAT_C PF08840.6 KND98872.1 - 0.031 13.9 0.2 10 5.7 0.0 2.8 1 1 2 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal IF4E PF01652.13 KND98873.1 - 6.5e-58 194.9 0.6 8.1e-58 194.5 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Aa_trans PF01490.13 KND98875.1 - 6.3e-79 265.3 33.5 9.9e-79 264.7 23.2 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein ApoO PF09769.4 KND98876.1 - 2e-25 89.3 1.1 5.9e-25 87.8 0.1 1.9 2 0 0 2 2 2 1 Apolipoprotein O ApbA_C PF08546.6 KND98877.1 - 4e-10 39.7 0.0 8.5e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal HAUS-augmin3 PF14932.1 KND98877.1 - 0.028 13.6 19.1 0.029 13.5 9.7 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF342 PF03961.8 KND98877.1 - 0.15 10.4 14.9 0.014 13.8 6.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF342) GLE1 PF07817.8 KND98877.1 - 1 8.2 7.6 1 8.2 4.4 1.5 1 1 0 1 1 1 0 GLE1-like protein DUF3552 PF12072.3 KND98877.1 - 3.2 6.9 29.4 0.3 10.2 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) GAS PF13851.1 KND98877.1 - 4.4 6.4 25.2 0.13 11.4 12.5 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Tup_N PF08581.5 KND98877.1 - 5.4 7.2 20.4 12 6.1 5.1 2.7 1 1 1 2 2 2 0 Tup N-terminal Thymidylate_kin PF02223.12 KND98880.1 - 8.5e-39 132.8 0.0 1e-38 132.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.1 KND98880.1 - 1.5e-05 25.3 0.0 3.3e-05 24.1 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 KND98880.1 - 0.00025 21.8 0.0 0.00039 21.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KND98880.1 - 0.0036 17.1 0.0 0.0057 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 KND98880.1 - 0.048 13.2 0.0 0.16 11.5 0.0 1.8 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_14 PF13173.1 KND98880.1 - 0.13 12.1 0.1 0.81 9.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain KTI12 PF08433.5 KND98880.1 - 0.15 11.1 0.0 0.31 10.2 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Clat_adaptor_s PF01217.15 KND98881.1 - 5.1e-50 168.8 4.9 5.8e-50 168.6 3.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TFIID_90kDa PF04494.10 KND98881.1 - 0.041 13.9 2.0 0.051 13.6 1.4 1.3 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit Ku PF02735.11 KND98882.1 - 2.6e-16 59.6 0.2 4e-15 55.7 0.2 2.6 1 1 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KND98882.1 - 0.003 17.0 1.6 0.0084 15.5 1.1 1.8 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 KND98882.1 - 0.015 15.8 0.4 0.015 15.8 0.3 3.9 4 0 0 4 4 4 0 Ku70/Ku80 C-terminal arm PKK PF12474.3 KND98890.1 - 0.021 14.5 0.9 0.022 14.4 0.6 1.0 1 0 0 1 1 1 0 Polo kinase kinase Zn_clus PF00172.13 KND98892.1 - 2.3e-08 33.7 15.3 3.5e-08 33.2 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2293 PF10056.4 KND98892.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2293) His_Phos_1 PF00300.17 KND98893.1 - 4.7e-10 39.7 0.0 9.1e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HEAT PF02985.17 KND98894.1 - 3.2e-38 126.3 14.4 0.00098 19.0 0.0 12.6 13 0 0 13 13 13 8 HEAT repeat HEAT_2 PF13646.1 KND98894.1 - 3.5e-29 100.9 0.1 1.1e-08 35.2 0.0 7.7 2 2 5 7 7 7 6 HEAT repeats Vac14_Fab1_bd PF12755.2 KND98894.1 - 1.2e-10 41.6 2.1 0.0054 17.1 0.0 6.3 6 2 1 7 7 7 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KND98894.1 - 5e-08 33.2 8.3 0.75 10.3 0.0 8.4 8 1 1 9 9 9 2 HEAT-like repeat Adaptin_N PF01602.15 KND98894.1 - 4.8e-06 25.1 6.5 0.0033 15.7 0.3 3.7 1 1 2 3 3 3 3 Adaptin N terminal region DUF2435 PF10363.4 KND98894.1 - 0.025 14.4 4.4 0.86 9.5 0.1 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) API5 PF05918.6 KND98894.1 - 0.043 12.3 0.3 0.19 10.2 0.1 2.1 1 1 1 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Ecm29 PF13001.2 KND98894.1 - 0.074 11.5 2.2 2.4 6.5 0.0 2.6 2 1 0 2 2 2 0 Proteasome stabiliser DUF1546 PF07571.8 KND98894.1 - 0.088 12.9 0.1 2.5 8.2 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1546) Cohesin_HEAT PF12765.2 KND98894.1 - 4.2 7.4 8.0 70 3.5 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Fe-S_biosyn PF01521.15 KND98895.1 - 1.3e-12 47.5 0.1 2.1e-12 46.9 0.1 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis PMT PF02366.13 KND98896.1 - 3.1e-86 288.7 18.7 3.1e-86 288.7 13.0 2.7 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KND98896.1 - 1.1e-27 96.7 0.0 1.9e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.1 KND98896.1 - 1.4e-08 34.7 11.2 1.4e-08 34.7 7.8 2.5 4 0 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Gp_dh_C PF02800.15 KND98900.1 - 7.2e-72 239.9 0.0 1e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KND98900.1 - 2.6e-59 199.5 0.1 4e-59 198.8 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 KND98900.1 - 0.014 15.2 0.0 0.062 13.2 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DUF2436 PF10365.4 KND98900.1 - 0.076 12.6 0.7 0.14 11.7 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) SPX PF03105.14 KND98902.1 - 1.7e-10 41.1 14.1 2e-08 34.3 0.0 3.1 3 1 1 4 4 4 2 SPX domain DUF1265 PF06887.9 KND98902.1 - 0.38 10.4 4.1 1.9 8.2 0.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1265) NIR_SIR PF01077.17 KND98904.1 - 9.1e-50 168.0 0.0 1.6e-47 160.7 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 KND98904.1 - 6.1e-31 105.8 0.0 3.6e-14 52.1 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 KND98904.1 - 2.5e-27 95.6 0.1 6.4e-27 94.2 0.0 1.8 1 0 0 1 1 1 1 Flavodoxin VWA_2 PF13519.1 KND98906.1 - 6.6e-11 42.6 0.1 9.1e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 KND98906.1 - 0.0003 20.4 0.0 0.00041 20.0 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 KND98906.1 - 0.00078 19.2 0.5 0.0014 18.4 0.3 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 KND98906.1 - 0.0011 18.3 0.8 0.0028 17.0 0.6 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif Prp18 PF02840.10 KND98906.1 - 0.1 12.4 0.3 0.21 11.3 0.2 1.4 1 0 0 1 1 1 0 Prp18 domain CRF PF00473.12 KND98906.1 - 0.39 10.8 2.9 1.1 9.3 2.0 1.8 1 0 0 1 1 1 0 Corticotropin-releasing factor family Phage_T4_Ndd PF06591.6 KND98907.1 - 0.009 15.5 0.0 0.033 13.7 0.0 2.0 2 0 0 2 2 2 1 T4-like phage nuclear disruption protein (Ndd) Swi3 PF07962.7 KND98908.1 - 4e-16 58.4 0.2 7.9e-16 57.4 0.1 1.5 1 1 0 1 1 1 1 Replication Fork Protection Component Swi3 Phage_P2_GpE PF06528.7 KND98909.1 - 0.031 13.7 0.1 0.047 13.1 0.1 1.3 1 0 0 1 1 1 0 Phage P2 GpE TB2_DP1_HVA22 PF03134.14 KND98911.1 - 0.061 13.0 6.0 0.13 12.0 4.1 1.5 1 0 0 1 1 1 0 TB2/DP1, HVA22 family HECT_2 PF09814.4 KND98913.1 - 3.3e-62 210.2 2.0 4.1e-62 209.9 1.4 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Fapy_DNA_glyco PF01149.19 KND98913.1 - 0.035 14.4 0.0 0.051 13.9 0.0 1.3 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase N-terminal domain DHHA2 PF02833.9 KND98914.1 - 7e-25 87.6 0.0 1.4e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 KND98914.1 - 4.1e-13 49.2 0.0 8.3e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 DHH family PMT PF02366.13 KND98915.1 - 1.3e-74 250.6 24.0 1.3e-74 250.6 16.6 1.9 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KND98915.1 - 1.3e-15 57.4 0.1 2.5e-15 56.5 0.1 1.4 1 0 0 1 1 1 1 MIR domain Hamartin PF04388.7 KND98916.1 - 2.1e-12 46.5 0.3 2.1e-12 46.5 0.2 2.5 2 1 0 2 2 2 1 Hamartin protein Pox_A_type_inc PF04508.7 KND98916.1 - 0.012 15.3 4.6 0.36 10.7 1.2 3.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Filament PF00038.16 KND98916.1 - 0.16 11.4 26.2 0.018 14.5 14.0 2.4 2 1 0 2 2 2 0 Intermediate filament protein DivIC PF04977.10 KND98916.1 - 2 7.9 6.6 1 8.9 0.8 3.0 2 0 0 2 2 2 0 Septum formation initiator DUF4404 PF14357.1 KND98916.1 - 10 6.6 11.4 17 5.9 1.1 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) MFS_1 PF07690.11 KND98918.1 - 7.8e-40 136.6 35.1 5.7e-39 133.8 19.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KND98918.1 - 2.6e-07 29.2 2.2 3.9e-07 28.6 1.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PQ-loop PF04193.9 KND98920.1 - 6.4e-22 76.8 7.8 2.4e-17 62.2 1.8 2.5 2 0 0 2 2 2 2 PQ loop repeat Rad4 PF03835.10 KND98921.1 - 1.4e-27 95.8 2.3 5.5e-27 93.9 1.6 2.0 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 KND98921.1 - 4.4e-20 70.9 0.0 8.8e-20 69.9 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_3 PF10405.4 KND98921.1 - 1.2e-13 50.5 0.0 2.4e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.4 KND98921.1 - 6.8e-10 39.1 0.3 3.8e-09 36.7 0.2 2.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KND98921.1 - 0.0071 16.5 0.0 0.02 15.1 0.0 1.7 1 1 0 1 1 1 1 Transglutaminase-like superfamily Lyase_1 PF00206.15 KND98924.1 - 1.4e-116 389.0 0.0 1.9e-116 388.6 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 KND98924.1 - 1e-25 89.5 0.0 2.2e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus AATase PF07247.7 KND98925.1 - 2.3e-69 234.2 0.2 3e-69 233.8 0.1 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 KND98925.1 - 2.9e-05 23.0 0.0 9.6e-05 21.3 0.0 1.7 2 0 0 2 2 2 1 Condensation domain HK PF02110.10 KND98926.1 - 3.2e-71 239.3 0.0 5e-71 238.7 0.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 KND98926.1 - 5.3e-59 198.3 0.1 1.8e-57 193.3 0.0 2.2 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 KND98926.1 - 3.3e-05 23.2 0.0 0.0001 21.5 0.0 1.8 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Tox-REase-3 PF15647.1 KND98926.1 - 0.08 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 3 WLM PF08325.5 KND98927.1 - 1.7e-43 148.6 0.0 4.2e-43 147.3 0.0 1.7 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.12 KND98927.1 - 0.01 15.6 0.2 0.01 15.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF45 INSIG PF07281.7 KND98928.1 - 1.3e-19 70.3 1.9 2.1e-19 69.6 1.3 1.4 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) DUF2198 PF09964.4 KND98928.1 - 0.4 10.4 4.7 1.8 8.3 0.8 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) Autophagy_act_C PF03987.10 KND98930.1 - 0.02 15.0 0.3 1.4 9.1 0.1 2.5 2 0 0 2 2 2 0 Autophagocytosis associated protein, active-site domain DUF4258 PF14076.1 KND98930.1 - 0.056 13.4 0.0 0.085 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) Endosulfine PF04667.12 KND98931.1 - 1.3e-28 98.8 0.6 1.7e-28 98.4 0.4 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region S-antigen PF05756.6 KND98931.1 - 0.041 13.8 0.1 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 S-antigen protein Pga1 PF10333.4 KND98932.1 - 8e-09 35.3 4.0 2.3e-08 33.9 2.8 1.6 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator F-box-like PF12937.2 KND98933.1 - 0.045 13.4 0.9 0.41 10.4 0.1 2.6 2 0 0 2 2 2 0 F-box-like P12 PF12669.2 KND98934.1 - 0.022 14.9 0.2 0.022 14.9 0.2 1.9 2 0 0 2 2 2 0 Virus attachment protein p12 family DUF4010 PF13194.1 KND98934.1 - 0.031 13.5 0.3 0.034 13.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) NVEALA PF14055.1 KND98934.1 - 0.074 12.7 2.2 0.44 10.2 0.0 2.2 2 0 0 2 2 2 0 NVEALA protein DUF2079 PF09852.4 KND98934.1 - 0.077 11.7 0.3 0.088 11.5 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) CoxIIa PF08113.6 KND98934.1 - 0.11 12.2 3.0 3 7.6 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family DUF4307 PF14155.1 KND98934.1 - 3.5 7.4 7.0 0.47 10.2 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4307) DUF347 PF03988.7 KND98934.1 - 4.3 7.3 6.5 1.3 8.9 0.4 2.1 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) CFEM PF05730.6 KND98936.1 - 3e-13 49.3 6.4 4.2e-13 48.9 4.5 1.2 1 0 0 1 1 1 1 CFEM domain Septin PF00735.13 KND98938.1 - 5.3e-90 301.2 0.1 8.9e-90 300.5 0.1 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KND98938.1 - 0.00035 20.5 0.0 0.00079 19.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KND98938.1 - 0.00049 19.6 3.3 0.037 13.4 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 KND98938.1 - 0.0065 16.6 0.0 0.07 13.2 0.0 2.5 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 KND98938.1 - 0.013 14.3 0.0 0.032 13.1 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF258 PF03193.11 KND98938.1 - 0.018 14.2 0.0 0.035 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 KND98938.1 - 0.05 12.8 0.7 0.08 12.1 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 KND98938.1 - 0.05 13.8 0.0 0.34 11.1 0.0 2.4 3 0 0 3 3 3 0 ABC transporter Pox_A32 PF04665.7 KND98938.1 - 0.051 12.8 0.1 0.093 12.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_16 PF13191.1 KND98938.1 - 0.052 13.5 0.2 0.67 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 KND98938.1 - 0.077 13.8 0.4 0.96 10.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KND98938.1 - 0.15 11.4 0.0 0.43 9.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Med28 PF11594.3 KND98938.1 - 5.5 7.2 8.4 5.4 7.3 2.0 3.0 2 1 1 3 3 3 0 Mediator complex subunit 28 PIN_4 PF13638.1 KND98939.1 - 6.1e-05 23.1 0.0 0.00065 19.8 0.0 2.2 2 0 0 2 2 2 1 PIN domain DUF792 PF05632.6 KND98939.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.5 2 0 0 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF792) SNF2_N PF00176.18 KND98940.1 - 3.4e-82 275.6 2.1 3.4e-82 275.6 1.5 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 KND98940.1 - 3e-21 75.1 0.2 9.3e-21 73.5 0.1 1.9 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 KND98940.1 - 4.2e-19 68.1 0.5 1.7e-16 59.8 0.0 3.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.1 KND98940.1 - 2.9e-14 52.9 10.2 2.9e-14 52.9 7.1 3.5 2 1 1 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 KND98940.1 - 0.0013 18.4 7.7 0.0087 15.8 5.3 2.5 1 0 0 1 1 1 1 HSA Tho2 PF11262.3 KND98940.1 - 1.4 7.9 15.3 0.011 14.8 3.6 2.6 3 0 0 3 3 3 0 Transcription factor/nuclear export subunit protein 2 Vps36_ESCRT-II PF11605.3 KND98941.1 - 0.0017 18.1 0.1 0.0045 16.7 0.1 1.7 1 1 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 RrnaAD PF00398.15 KND98942.1 - 8.1e-25 87.3 0.0 1e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 KND98942.1 - 0.01 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MarB PF13999.1 KND98943.1 - 0.038 13.5 0.1 0.17 11.5 0.0 2.1 2 0 0 2 2 2 0 MarB protein Suf PF05843.9 KND98944.1 - 7.8e-64 216.0 10.8 6.5e-63 213.0 0.1 3.7 3 1 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_19 PF14559.1 KND98944.1 - 0.021 15.1 0.0 0.079 13.3 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat AnfO_nitrog PF09582.5 KND98944.1 - 0.084 11.9 1.9 0.26 10.3 0.0 2.3 2 0 0 2 2 2 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) TPR_16 PF13432.1 KND98944.1 - 0.12 13.1 0.0 0.89 10.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Tom37_C PF11801.3 KND98945.1 - 3.2e-47 160.5 1.9 4.2e-47 160.1 1.3 1.1 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 KND98945.1 - 2.9e-20 72.3 0.4 7.5e-20 70.9 0.3 1.8 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein DUF4448 PF14610.1 KND98946.1 - 1.2e-60 204.2 0.5 1.2e-60 204.2 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) Zip PF02535.17 KND98948.1 - 3.1e-25 88.8 23.6 2.1e-24 86.1 16.4 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3784 PF12650.2 KND98948.1 - 0.2 11.6 4.7 0.22 11.5 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) UIM PF02809.15 KND98948.1 - 2.4 7.9 5.4 0.33 10.6 0.8 1.9 2 0 0 2 2 2 0 Ubiquitin interaction motif PNRC PF15365.1 KND98949.1 - 2.5e-05 24.1 4.6 2.5e-05 24.1 3.2 2.8 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator Oxidored_q1 PF00361.15 KND98950.1 - 5.8e-14 51.9 6.5 6.3e-14 51.8 4.5 1.0 1 0 0 1 1 1 1 NADH-Ubiquinone/plastoquinone (complex I), various chains 7TMR-DISM_7TM PF07695.6 KND98950.1 - 0.15 11.6 9.0 0.18 11.4 6.2 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling Zip PF02535.17 KND98950.1 - 0.63 8.9 3.2 0.65 8.9 2.2 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2775 PF10950.3 KND98952.1 - 0.057 13.6 0.7 0.061 13.5 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2775) Oxidored_q1 PF00361.15 KND98954.1 - 1.8e-21 76.6 6.8 1.8e-21 76.6 4.7 2.3 2 1 0 2 2 2 1 NADH-Ubiquinone/plastoquinone (complex I), various chains NADH5_C PF06455.6 KND98954.1 - 1.1e-06 28.1 1.2 1.1e-06 28.1 0.9 2.5 2 1 0 2 2 2 1 NADH dehydrogenase subunit 5 C-terminus LAGLIDADG_1 PF00961.14 KND98955.1 - 3e-09 37.3 5.3 3e-09 37.3 3.7 1.7 1 1 1 2 2 2 1 LAGLIDADG endonuclease LAGLIDADG_3 PF14528.1 KND98955.1 - 0.018 15.2 3.4 0.069 13.3 2.3 2.2 1 1 0 1 1 1 0 LAGLIDADG-like domain Vps8 PF12816.2 KND98955.1 - 0.025 13.8 0.4 0.027 13.7 0.3 1.1 1 0 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 LAGLIDADG_1 PF00961.14 KND98956.1 - 2.4e-08 34.4 3.3 3e-08 34.1 2.3 1.2 1 0 0 1 1 1 1 LAGLIDADG endonuclease LAGLIDADG_1 PF00961.14 KND98957.1 - 0.0001 22.8 11.4 0.00012 22.5 7.9 1.1 1 0 0 1 1 1 1 LAGLIDADG endonuclease CRS1_YhbY PF01985.16 KND98959.1 - 0.0067 16.4 0.3 0.0067 16.4 0.2 1.0 1 0 0 1 1 1 1 CRS1 / YhbY (CRM) domain SnoaL_3 PF13474.1 KND98964.1 - 0.85 9.6 3.6 5.5 7.0 0.0 3.1 3 0 0 3 3 3 0 SnoaL-like domain Nanovirus_coat PF04660.7 KND98964.1 - 2.7 7.6 6.7 37 3.9 0.1 3.6 4 0 0 4 4 4 0 Nanovirus coat protein Rib PF08428.5 KND98965.1 - 0.13 12.0 0.7 0.68 9.7 0.5 2.0 1 1 0 1 1 1 0 Rib/alpha-like repeat ABC_tran PF00005.22 KND98968.1 - 7.6e-09 35.9 0.0 8.4e-09 35.8 0.0 1.0 1 0 0 1 1 1 1 ABC transporter Nuc_N PF14448.1 KND98968.1 - 0.34 10.5 1.7 5.3 6.6 0.1 2.4 2 1 0 2 2 2 0 Nuclease N terminal Flavi_capsid PF01003.14 KND98971.1 - 0.41 10.1 2.8 0.42 10.1 1.9 1.1 1 0 0 1 1 1 0 Flavivirus capsid protein C Rep_fac-A_3 PF08661.6 KND98973.1 - 0.75 9.7 3.7 0.66 9.8 1.2 1.7 1 1 1 2 2 2 0 Replication factor A protein 3 DUF1034 PF06280.7 KND98974.1 - 1.5 9.2 7.4 1.4 9.3 1.0 2.1 1 1 1 2 2 2 0 Fn3-like domain (DUF1034) Colicin_C PF12106.3 KND98975.1 - 0.21 11.1 3.7 2.8 7.5 2.5 2.5 1 1 0 1 1 1 0 Colicin C terminal ribonuclease domain NUT_N PF12881.2 KND98976.1 - 0.55 9.3 4.8 0.65 9.0 3.3 1.0 1 0 0 1 1 1 0 NUT protein N terminus Coatamer_beta_C PF07718.7 KND98976.1 - 1.3 8.6 4.4 10 5.7 1.4 2.6 1 1 2 3 3 3 0 Coatomer beta C-terminal region Imm33 PF15580.1 KND98977.1 - 3.2e-13 48.9 43.0 4.1 6.9 0.0 19.7 21 0 0 21 21 21 6 Immunity protein 33 PPV_E2_C PF00511.12 KND98977.1 - 8.3e-11 41.6 132.4 0.46 10.4 0.4 22.0 4 4 19 23 23 23 16 E2 (early) protein, C terminal FTP PF07504.8 KND98977.1 - 2.6e-05 23.6 113.8 0.62 9.5 0.4 23.4 24 1 0 24 24 24 14 Fungalysin/Thermolysin Propeptide Motif Hyphal_reg_CWP PF11765.3 KND98979.1 - 5e-54 183.2 10.0 7.2e-54 182.7 7.0 1.1 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal LIP PF03583.9 KND98980.1 - 3.3e-94 315.3 0.0 6.8e-94 314.3 0.0 1.5 2 0 0 2 2 2 1 Secretory lipase Abhydrolase_5 PF12695.2 KND98980.1 - 3.2e-05 23.7 0.0 6.2e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND98980.1 - 7.9e-05 22.6 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KND98980.1 - 0.0055 15.9 0.1 0.43 9.7 0.0 2.4 2 1 0 2 2 2 1 Prolyl oligopeptidase family RasGEF_N_2 PF14663.1 KND98981.1 - 0.097 12.6 2.4 0.096 12.6 0.8 1.7 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Sec63 PF02889.11 KND98981.1 - 4.1 6.5 8.5 4.8 6.3 5.9 1.2 1 0 0 1 1 1 0 Sec63 Brl domain MFS_1 PF07690.11 KND98987.1 - 7.3e-28 97.2 17.8 7.3e-28 97.2 12.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KND98987.1 - 0.00056 18.2 1.2 0.00086 17.6 0.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Branch PF02485.16 KND98988.1 - 0.055 12.6 0.0 0.057 12.5 0.0 1.1 1 0 0 1 1 1 0 Core-2/I-Branching enzyme adh_short PF00106.20 KND98989.1 - 9.2e-31 107.0 0.8 1.6e-30 106.2 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND98989.1 - 1.9e-23 83.4 0.3 2.3e-23 83.2 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND98989.1 - 2e-11 43.8 0.5 3e-11 43.3 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KND98989.1 - 4.2e-05 23.0 0.0 0.027 13.8 0.0 2.0 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Peripla_BP_6 PF13458.1 KND98989.1 - 0.046 13.0 0.3 0.091 12.0 0.2 1.5 1 1 0 1 1 1 0 Periplasmic binding protein Ldh_1_N PF00056.18 KND98989.1 - 0.1 12.4 0.2 0.26 11.1 0.2 1.7 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain P5CR_dimer PF14748.1 KND98989.1 - 0.82 9.7 3.5 1.3 9.0 0.4 2.5 3 0 0 3 3 3 0 Pyrroline-5-carboxylate reductase dimerisation Pro_isomerase PF00160.16 KND98990.1 - 1.7e-45 155.0 0.2 1.7e-45 155.0 0.2 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 KND98990.1 - 2.8e-07 30.0 4.8 0.00017 21.1 0.7 2.3 2 0 0 2 2 2 2 TPR repeat DUF1386 PF07138.6 KND98990.1 - 0.0048 16.0 0.0 0.0062 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1386) TPR_2 PF07719.12 KND98990.1 - 0.006 16.4 0.2 0.006 16.4 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KND98990.1 - 0.01 15.3 1.5 0.038 13.6 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 KND98990.1 - 0.043 13.6 2.4 4.5 7.2 0.0 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.1 KND98990.1 - 0.1 12.4 0.0 0.1 12.4 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 KND98991.1 - 2.5e-55 187.4 0.1 2.9e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND98991.1 - 1.3e-16 60.4 0.0 2.6e-16 59.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KND98991.1 - 1.2e-05 25.1 0.0 0.00056 19.7 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KND98991.1 - 0.014 14.9 0.1 0.026 14.0 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase ABC1 PF03109.11 KND98991.1 - 0.13 12.1 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 ABC1 family LTV PF04180.9 KND98992.1 - 1.8e-73 248.4 36.7 5.8e-73 246.8 25.4 1.7 1 1 0 1 1 1 1 Low temperature viability protein MatE PF01554.13 KND98993.1 - 7.7e-52 175.1 35.0 1.3e-27 96.3 6.0 3.2 4 0 0 4 4 4 2 MatE Polysacc_synt_C PF14667.1 KND98993.1 - 0.00014 21.7 22.7 0.00039 20.2 9.0 4.8 3 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Subtilosin_A PF11420.3 KND98994.1 - 0.017 15.1 0.0 0.022 14.7 0.0 1.1 1 0 0 1 1 1 0 Bacteriocin subtilosin A PIH1 PF08190.7 KND98995.1 - 1.2e-25 90.7 0.0 1.4e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 BPL_N PF09825.4 KND98996.1 - 5.7e-128 426.7 0.0 8.1e-128 426.2 0.0 1.2 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 KND98996.1 - 5.5e-11 42.5 0.0 1.2e-10 41.4 0.0 1.6 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 KND98996.1 - 4.3e-08 32.7 0.1 8.2e-08 31.8 0.1 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain zf-Apc11 PF12861.2 KND98997.1 - 7.9e-44 147.4 8.2 1e-43 147.1 5.7 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KND98997.1 - 4.4e-30 103.5 8.9 5.9e-30 103.1 6.2 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KND98997.1 - 1.2e-06 28.2 16.2 5.6e-06 26.0 11.1 2.3 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 KND98997.1 - 0.0054 16.5 1.1 0.0054 16.5 0.7 2.2 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KND98997.1 - 0.011 15.2 11.2 0.021 14.4 0.4 3.0 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 KND98997.1 - 0.011 15.3 13.6 0.061 12.9 9.4 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-PHD-like PF15446.1 KND98997.1 - 0.025 13.9 1.0 0.035 13.3 0.7 1.3 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-HIT PF04438.11 KND98997.1 - 0.052 13.1 1.6 0.052 13.1 1.1 2.2 2 0 0 2 2 2 0 HIT zinc finger zf-C3HC4_2 PF13923.1 KND98997.1 - 0.071 13.1 14.3 0.51 10.4 9.9 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND98997.1 - 0.095 12.4 11.2 0.37 10.5 7.8 2.1 1 1 0 1 1 1 0 zinc-RING finger domain zf-met2 PF12907.2 KND98997.1 - 0.12 12.3 0.1 0.12 12.3 0.1 3.0 3 1 0 3 3 3 0 Zinc-binding zf-RING-like PF08746.6 KND98997.1 - 0.23 11.4 11.0 1.2 9.2 7.6 2.2 1 1 0 1 1 1 0 RING-like domain PHD PF00628.24 KND98997.1 - 0.4 10.4 10.8 0.051 13.2 4.5 1.8 2 0 0 2 2 2 0 PHD-finger zf-C3HC4_3 PF13920.1 KND98997.1 - 0.55 9.9 12.6 18 5.0 8.8 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 KND98997.1 - 0.66 10.0 6.5 3.7 7.6 0.0 3.2 2 1 0 2 2 2 0 zinc-finger DZR PF12773.2 KND98997.1 - 1.4 8.8 7.5 3.9 7.3 1.4 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-Di19 PF05605.7 KND98997.1 - 4.3 7.5 9.0 3.5e+02 1.4 4.7 3.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding RINGv PF12906.2 KND98997.1 - 6.5 6.8 11.3 13 5.8 7.3 2.0 1 1 1 2 2 2 0 RING-variant domain UbiA PF01040.13 KND98999.1 - 3.1e-29 101.9 18.5 4e-29 101.6 12.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family CNH PF00780.17 KND99000.1 - 0.00049 19.5 0.0 0.00087 18.7 0.0 1.4 1 0 0 1 1 1 1 CNH domain Vps39_2 PF10367.4 KND99000.1 - 0.0031 17.6 0.1 0.019 15.1 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 AA_kinase PF00696.23 KND99001.1 - 9.7e-36 123.5 1.0 1.3e-35 123.0 0.7 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 KND99001.1 - 7.2e-15 54.4 0.5 1.4e-14 53.5 0.0 1.8 2 0 0 2 2 2 1 PUA domain RF-1 PF00472.15 KND99002.1 - 2.5e-24 85.2 3.5 3.7e-24 84.7 2.4 1.3 1 0 0 1 1 1 1 RF-1 domain MIR PF02815.14 KND99002.1 - 0.012 15.1 0.1 0.015 14.8 0.1 1.2 1 0 0 1 1 1 0 MIR domain DUF2361 PF10153.4 KND99002.1 - 0.13 12.4 9.9 0.22 11.7 6.9 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) Mgr1 PF08602.5 KND99002.1 - 0.19 10.6 1.7 0.24 10.3 1.2 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DUF4167 PF13763.1 KND99002.1 - 0.97 9.4 5.7 1.9 8.5 3.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4167) DUF1713 PF08213.6 KND99002.1 - 7.6 6.2 12.5 0.38 10.4 4.3 2.1 2 0 0 2 2 2 0 Mitochondrial domain of unknown function (DUF1713) Lipase_GDSL_2 PF13472.1 KND99004.1 - 1.3e-23 84.0 0.0 1.7e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KND99004.1 - 4.8e-20 72.3 0.0 5.8e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Cellulase PF00150.13 KND99004.1 - 0.0083 15.3 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GARS_N PF02844.10 KND99004.1 - 0.0086 16.5 0.0 0.019 15.4 0.0 1.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain ABC_tran PF00005.22 KND99005.1 - 2.4e-49 167.1 0.1 3.9e-24 85.5 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 KND99005.1 - 3.4e-21 74.8 0.9 3.4e-21 74.8 0.6 3.3 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.1 KND99005.1 - 3e-20 73.3 2.5 1.6e-05 25.0 0.0 4.3 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 KND99005.1 - 8e-11 41.5 0.5 0.17 11.0 0.0 4.4 3 1 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KND99005.1 - 9.1e-09 34.7 0.0 0.00049 19.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KND99005.1 - 2.7e-08 34.6 0.0 0.011 16.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 KND99005.1 - 1e-07 32.1 0.1 0.022 14.9 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.1 KND99005.1 - 2.2e-07 31.0 4.2 0.0076 16.2 0.0 3.3 4 1 0 4 4 2 2 AAA ATPase domain AAA_18 PF13238.1 KND99005.1 - 2.6e-07 30.9 0.1 0.0083 16.4 0.0 3.2 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 KND99005.1 - 3.9e-07 30.5 0.2 0.0066 16.9 0.0 3.0 3 0 0 3 3 2 2 Miro-like protein DUF258 PF03193.11 KND99005.1 - 7.2e-07 28.5 0.0 0.0024 17.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KND99005.1 - 5e-06 26.9 7.6 0.04 14.2 0.0 4.1 4 0 0 4 4 3 2 AAA domain AAA_28 PF13521.1 KND99005.1 - 7.4e-06 26.0 0.2 0.033 14.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain NACHT PF05729.7 KND99005.1 - 8.4e-06 25.5 0.2 0.12 12.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_14 PF13173.1 KND99005.1 - 2.9e-05 23.9 0.0 0.44 10.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KND99005.1 - 3.4e-05 23.5 0.1 0.24 11.1 0.1 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KND99005.1 - 4e-05 23.7 0.1 0.6 10.3 0.0 3.1 3 0 0 3 3 2 2 RNA helicase MMR_HSR1 PF01926.18 KND99005.1 - 6.4e-05 22.8 0.5 0.3 11.0 0.1 3.3 3 1 0 3 3 2 2 50S ribosome-binding GTPase AAA_33 PF13671.1 KND99005.1 - 9.9e-05 22.2 0.1 0.36 10.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain MobB PF03205.9 KND99005.1 - 0.00013 21.6 0.1 0.02 14.6 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KND99005.1 - 0.00015 21.2 0.0 1.3 8.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.1 KND99005.1 - 0.00017 20.7 0.0 0.29 10.1 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.24 KND99005.1 - 0.00026 21.1 0.0 1.1 9.4 0.1 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KND99005.1 - 0.00048 19.6 0.1 1.8 7.9 0.1 3.2 3 0 0 3 3 3 2 AAA-like domain PduV-EutP PF10662.4 KND99005.1 - 0.0012 18.3 0.6 4.7 6.6 0.0 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 KND99005.1 - 0.0013 17.6 0.1 0.95 8.3 0.0 2.7 3 0 0 3 3 2 2 Protein of unknown function (DUF815) NB-ARC PF00931.17 KND99005.1 - 0.002 17.0 0.0 2.5 6.8 0.0 2.8 2 1 0 2 2 2 2 NB-ARC domain Arch_ATPase PF01637.13 KND99005.1 - 0.0022 17.7 5.4 0.49 10.0 0.0 3.5 4 0 0 4 4 4 2 Archaeal ATPase DAP3 PF10236.4 KND99005.1 - 0.0035 16.3 0.3 1.8 7.4 0.0 2.7 3 0 0 3 3 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.1 KND99005.1 - 0.0064 16.0 0.5 1.6 8.2 0.0 3.0 4 0 0 4 4 2 1 AAA domain SbcCD_C PF13558.1 KND99005.1 - 0.0082 16.0 0.5 0.34 10.8 0.1 3.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Ras PF00071.17 KND99005.1 - 0.0094 15.3 0.0 3.6 6.9 0.0 2.7 3 0 0 3 3 3 0 Ras family Septin PF00735.13 KND99005.1 - 0.013 14.5 0.0 2.6 6.9 0.0 2.5 2 0 0 2 2 2 0 Septin MCM PF00493.18 KND99005.1 - 0.017 13.9 0.1 3.2 6.4 0.0 2.5 2 0 0 2 2 2 0 MCM2/3/5 family ArgK PF03308.11 KND99005.1 - 0.022 13.5 0.1 5.4 5.7 0.0 2.9 3 0 0 3 3 3 0 ArgK protein VirE PF05272.6 KND99005.1 - 0.023 14.1 0.1 6.8 6.1 0.0 3.0 3 0 0 3 3 3 0 Virulence-associated protein E NTPase_1 PF03266.10 KND99005.1 - 0.026 14.2 0.1 1.9 8.1 0.1 2.6 2 0 0 2 2 2 0 NTPase T2SE PF00437.15 KND99005.1 - 0.026 13.4 0.0 0.25 10.2 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP-synt_ab PF00006.20 KND99005.1 - 0.061 12.8 0.0 0.28 10.6 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.18 KND99005.1 - 0.61 9.8 5.1 5.9 6.6 0.0 3.5 3 1 1 4 4 4 0 Dynamin family DUF87 PF01935.12 KND99005.1 - 0.73 9.6 5.3 12 5.6 0.0 3.4 3 1 1 4 4 3 0 Domain of unknown function DUF87 AAA_13 PF13166.1 KND99005.1 - 0.79 8.1 9.1 14 4.0 0.0 3.9 4 0 0 4 4 4 0 AAA domain Utp12 PF04003.7 KND99006.1 - 4.1e-08 33.0 1.3 8.4e-08 32.0 0.9 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family PGA2 PF07543.7 KND99006.1 - 0.0093 15.7 0.1 0.0093 15.7 0.1 1.8 2 0 0 2 2 2 1 Protein trafficking PGA2 Pribosyltran PF00156.22 KND99007.1 - 2.3e-10 40.2 1.0 2e-09 37.2 0.7 2.1 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Syntaxin-6_N PF09177.6 KND99007.1 - 0.0038 17.6 0.0 0.0077 16.6 0.0 1.5 1 0 0 1 1 1 1 Syntaxin 6, N-terminal IBN_N PF03810.14 KND99010.1 - 5.3e-16 58.3 0.0 2.7e-15 56.0 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KND99010.1 - 6.9e-07 29.2 1.2 3.5e-06 26.9 0.1 2.8 2 0 0 2 2 2 1 Exportin 1-like protein Cse1 PF08506.5 KND99010.1 - 1.1e-05 24.2 0.0 3.2e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Cse1 DUF3437 PF11919.3 KND99011.1 - 7.2e-28 96.1 0.0 2.1e-27 94.6 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) TMF_TATA_bd PF12325.3 KND99012.1 - 6.1e-31 106.6 17.0 6.1e-31 106.6 11.8 6.8 2 1 4 6 6 6 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 KND99012.1 - 3.9e-11 42.6 14.1 3.9e-11 42.6 9.7 10.1 4 4 5 10 10 10 3 TATA element modulatory factor 1 DNA binding IncA PF04156.9 KND99012.1 - 0.00018 21.2 12.6 0.00018 21.2 8.7 6.0 2 1 3 5 5 5 2 IncA protein DrsE_2 PF13686.1 KND99012.1 - 7.9 6.2 11.2 0.19 11.5 2.1 2.5 2 0 0 2 2 2 0 DsrE/DsrF/DrsH-like family MAP65_ASE1 PF03999.7 KND99014.1 - 0.048 12.2 1.8 0.078 11.5 1.2 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DDRGK PF09756.4 KND99016.1 - 8.1 5.8 17.7 9.1 5.6 12.2 1.0 1 0 0 1 1 1 0 DDRGK domain Rubella_E1 PF05748.6 KND99019.1 - 0.06 11.9 0.1 0.063 11.8 0.1 1.0 1 0 0 1 1 1 0 Rubella membrane glycoprotein E1 Pox_D2 PF04701.8 KND99029.1 - 0.064 13.2 0.0 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 Pox virus D2 protein LRR_4 PF12799.2 KND99029.1 - 0.4 10.3 7.7 13 5.5 0.1 4.8 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) Sec2p PF06428.6 KND99033.1 - 4.2e-24 84.3 10.6 4.2e-24 84.3 7.4 3.1 2 2 1 3 3 3 1 GDP/GTP exchange factor Sec2p GAS PF13851.1 KND99033.1 - 0.00027 20.1 15.1 0.00027 20.1 10.5 3.4 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding DUF3287 PF11690.3 KND99033.1 - 0.012 15.6 1.5 0.063 13.3 1.1 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) FUSC PF04632.7 KND99033.1 - 0.03 12.7 0.8 0.048 12.0 0.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Reo_sigmaC PF04582.7 KND99033.1 - 0.4 9.8 3.9 0.81 8.7 2.7 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 KND99033.1 - 0.44 7.7 40.9 0.014 12.7 13.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) IncA PF04156.9 KND99033.1 - 1.6 8.3 43.4 0.091 12.3 10.6 3.2 2 1 1 3 3 3 0 IncA protein Spc7 PF08317.6 KND99033.1 - 8.7 4.9 34.3 0.25 9.9 11.8 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein FH2 PF02181.18 KND99036.1 - 6.7e-84 281.8 8.8 6.7e-84 281.8 6.1 3.1 4 1 0 4 4 4 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 KND99036.1 - 4.1e-48 163.3 0.1 4.1e-48 163.3 0.1 5.0 5 1 0 5 5 5 2 Diaphanous FH3 Domain Drf_GBD PF06371.8 KND99036.1 - 5.8e-35 120.3 0.5 5.8e-35 120.3 0.3 3.5 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain MMS1_N PF10433.4 KND99037.1 - 5.8e-88 295.2 0.0 9.3e-88 294.5 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Pup_ligase PF03136.10 KND99037.1 - 0.42 9.1 0.0 0.63 8.5 0.0 1.2 1 0 0 1 1 1 0 Pup-ligase protein Sugar_tr PF00083.19 KND99040.1 - 4.2e-09 35.5 20.9 5.8e-09 35.0 14.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MrpF_PhaF PF04066.8 KND99040.1 - 0.0095 16.1 0.2 0.0095 16.1 0.2 2.9 3 0 0 3 3 3 1 Multiple resistance and pH regulation protein F (MrpF / PhaF) Yip1 PF04893.12 KND99041.1 - 9.7e-14 51.2 6.0 9.7e-14 51.2 4.1 1.3 2 0 0 2 2 2 1 Yip1 domain DUF4231 PF14015.1 KND99041.1 - 5.4 7.0 6.1 1.9 8.4 1.6 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF4231) Pkinase PF00069.20 KND99042.1 - 1.7e-55 187.9 0.0 2e-55 187.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND99042.1 - 4.8e-33 114.3 0.0 5.5e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND99042.1 - 5.9e-05 22.1 0.0 0.00011 21.2 0.0 1.4 1 1 0 1 1 1 1 Kinase-like PPR_3 PF13812.1 KND99043.1 - 2.2e-08 33.7 2.6 0.091 13.0 0.0 6.5 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 KND99043.1 - 2.7e-07 30.4 3.5 0.032 14.2 0.0 4.4 5 1 1 6 6 6 2 PPR repeat family PPR PF01535.15 KND99043.1 - 0.00079 19.2 3.6 15 5.8 0.0 5.9 6 0 0 6 6 6 2 PPR repeat TPR_14 PF13428.1 KND99043.1 - 0.062 13.9 0.1 31 5.5 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KND99043.1 - 1.3 9.1 4.2 51 4.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat SPC22 PF04573.7 KND99044.1 - 4.8e-48 162.6 0.3 5.8e-48 162.4 0.2 1.0 1 0 0 1 1 1 1 Signal peptidase subunit tRNA-synt_1e PF01406.14 KND99045.1 - 2.3e-133 443.9 0.3 2.3e-133 443.9 0.2 2.0 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KND99045.1 - 1.1e-07 30.8 9.5 8e-06 24.7 0.1 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KND99045.1 - 6.9e-06 24.3 6.9 4.8e-05 21.5 0.0 3.2 3 1 1 4 4 4 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.13 KND99045.1 - 2.8e-05 22.9 0.1 0.00076 18.2 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (K) GTP_EFTU PF00009.22 KND99049.1 - 2.5e-59 199.8 0.1 5.5e-59 198.7 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KND99049.1 - 7.7e-31 106.1 0.1 2.8e-30 104.3 0.1 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.1 KND99049.1 - 1.4e-28 98.5 0.0 2.8e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KND99049.1 - 8e-22 76.9 0.1 1.8e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KND99049.1 - 6.5e-11 42.1 0.1 1.8e-10 40.8 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 KND99049.1 - 0.043 14.2 0.0 0.12 12.8 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein DUF442 PF04273.8 KND99049.1 - 0.073 12.9 0.0 4.4 7.2 0.0 2.7 2 0 0 2 2 2 0 Putative phosphatase (DUF442) FA_desaturase PF00487.19 KND99052.1 - 4.1e-22 78.8 21.1 6.4e-22 78.2 14.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KND99052.1 - 5.1e-06 26.5 0.0 8.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Chitin_synth_2 PF03142.10 KND99054.1 - 1.8e-278 924.2 0.2 1.8e-278 924.2 0.1 1.4 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KND99054.1 - 6.1e-17 61.9 3.8 3.3e-16 59.5 2.7 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KND99054.1 - 1.4e-12 47.9 0.0 7.2e-11 42.3 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 KND99054.1 - 0.00036 20.2 0.0 0.95 9.3 0.0 3.2 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 KND99054.1 - 0.0006 19.5 0.0 0.019 14.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KND99054.1 - 0.0024 17.1 0.0 0.0049 16.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Sec7_N PF12783.2 KND99056.1 - 1.3e-25 89.7 0.6 1.3e-25 89.7 0.4 4.1 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KND99056.1 - 0.0061 16.0 0.0 1.8 8.1 0.0 3.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) AAA_10 PF12846.2 KND99056.1 - 0.027 13.9 0.0 1.5 8.2 0.0 3.4 3 2 0 3 3 3 0 AAA-like domain Heme_oxygenase PF01126.15 KND99059.1 - 1.9e-22 79.8 3.6 3.6e-22 78.9 2.5 1.4 1 1 0 1 1 1 1 Heme oxygenase DUF2839 PF10999.3 KND99059.1 - 0.036 14.0 0.0 0.83 9.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) AAA_18 PF13238.1 KND99060.1 - 1.8e-26 92.9 0.5 1.8e-26 92.9 0.3 2.6 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 KND99060.1 - 3.5e-08 34.2 13.6 4.3e-07 30.7 9.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KND99060.1 - 3.4e-05 23.7 0.0 0.0042 16.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KND99060.1 - 0.00011 22.1 0.0 0.00029 20.8 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KND99060.1 - 0.0003 20.9 0.0 0.00082 19.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KND99060.1 - 0.00055 19.6 0.0 0.0012 18.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KND99060.1 - 0.00059 19.8 0.0 0.00059 19.8 0.0 2.4 2 1 0 2 2 1 1 AAA domain KTI12 PF08433.5 KND99060.1 - 0.00071 18.8 0.2 0.0022 17.2 0.0 1.8 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Viral_helicase1 PF01443.13 KND99060.1 - 0.00075 19.0 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA PF00004.24 KND99060.1 - 0.00083 19.5 0.0 0.0022 18.2 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KND99060.1 - 0.00083 19.2 0.3 0.0055 16.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KND99060.1 - 0.0021 18.2 0.1 0.0059 16.7 0.0 1.8 2 0 0 2 2 1 1 RNA helicase T2SE PF00437.15 KND99060.1 - 0.0034 16.3 0.0 0.0069 15.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Mg_chelatase PF01078.16 KND99060.1 - 0.0046 16.1 0.0 0.0073 15.4 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KND99060.1 - 0.0046 16.0 0.0 0.0091 15.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin NTPase_1 PF03266.10 KND99060.1 - 0.005 16.5 0.2 0.017 14.8 0.0 1.9 2 0 0 2 2 2 1 NTPase NACHT PF05729.7 KND99060.1 - 0.0064 16.1 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain GvpD PF07088.6 KND99060.1 - 0.013 13.8 0.0 0.024 12.9 0.0 1.3 1 1 0 1 1 1 0 GvpD gas vesicle protein Arch_ATPase PF01637.13 KND99060.1 - 0.018 14.7 0.0 0.018 14.7 0.0 2.6 2 1 0 2 2 1 0 Archaeal ATPase SRPRB PF09439.5 KND99060.1 - 0.022 14.0 0.3 0.078 12.1 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Na_trans_assoc PF06512.8 KND99060.1 - 0.022 14.7 17.4 0.026 14.4 12.1 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated AAA_10 PF12846.2 KND99060.1 - 0.028 13.8 1.4 0.044 13.2 0.9 1.8 1 1 0 1 1 1 0 AAA-like domain MobB PF03205.9 KND99060.1 - 0.04 13.6 0.0 0.04 13.6 0.0 2.0 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 KND99060.1 - 0.041 13.6 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 KND99060.1 - 0.051 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.22 KND99060.1 - 0.052 13.8 0.7 0.11 12.8 0.4 1.8 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.18 KND99060.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase PRK PF00485.13 KND99060.1 - 0.061 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family cobW PF02492.14 KND99060.1 - 0.074 12.4 0.5 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.12 KND99060.1 - 0.083 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Ycf1 PF05758.7 KND99060.1 - 0.085 10.5 6.9 0.11 10.2 4.8 1.1 1 0 0 1 1 1 0 Ycf1 Drc1-Sld2 PF11719.3 KND99060.1 - 0.3 10.1 15.5 0.31 10.0 10.8 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein PPP4R2 PF09184.6 KND99060.1 - 2 7.9 33.2 3.2 7.2 23.0 1.2 1 0 0 1 1 1 0 PPP4R2 DDHD PF02862.12 KND99060.1 - 2.8 7.6 10.5 3.7 7.2 7.3 1.3 1 0 0 1 1 1 0 DDHD domain VID27 PF08553.5 KND99060.1 - 3.4 5.7 23.7 5 5.2 16.4 1.3 1 0 0 1 1 1 0 VID27 cytoplasmic protein CobT PF06213.7 KND99060.1 - 3.5 6.6 27.6 5.8 5.9 19.1 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 KND99060.1 - 4.3 5.2 24.7 5.6 4.8 17.1 1.2 1 0 0 1 1 1 0 CDC45-like protein CENP-T PF15511.1 KND99060.1 - 5.6 6.0 16.5 6.9 5.8 11.4 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T AAA_11 PF13086.1 KND99060.1 - 5.7 6.4 11.7 9.3 5.7 8.1 1.4 1 1 0 1 1 1 0 AAA domain Herpes_DNAp_acc PF04929.7 KND99060.1 - 6.2 5.6 7.4 3.1 6.6 3.1 1.8 2 0 0 2 2 2 0 Herpes DNA replication accessory factor UPF0154 PF03672.8 KND99061.1 - 0.013 15.1 0.2 0.013 15.1 0.1 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Shisa PF13908.1 KND99061.1 - 0.021 15.0 0.1 0.024 14.8 0.1 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator FixQ PF05545.6 KND99061.1 - 0.11 12.1 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF347 PF03988.7 KND99063.1 - 0.18 11.7 2.7 0.42 10.5 1.9 1.6 1 1 0 1 1 1 0 Repeat of Unknown Function (DUF347) Aa_trans PF01490.13 KND99066.1 - 9.3e-30 103.4 38.1 1.1e-29 103.1 26.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Tyr_Deacylase PF02580.11 KND99067.1 - 6.2e-47 159.2 0.0 9e-47 158.7 0.0 1.2 1 1 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase LIP PF03583.9 KND99069.1 - 3.9e-99 331.5 0.1 9.3e-99 330.2 0.0 1.6 2 0 0 2 2 2 1 Secretory lipase Abhydrolase_6 PF12697.2 KND99069.1 - 4.5e-05 23.4 0.0 8.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND99069.1 - 0.00081 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KND99069.1 - 0.03 13.5 0.8 1.4 8.0 0.0 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KND99069.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase SecY PF00344.15 KND99070.1 - 2.7e-67 227.1 11.0 3.2e-67 226.8 7.6 1.0 1 0 0 1 1 1 1 SecY translocase DMRL_synthase PF00885.14 KND99072.1 - 2.1e-47 160.3 0.0 2.7e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DUF2085 PF09858.4 KND99075.1 - 0.14 12.2 0.2 0.16 12.0 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2085) zf-CHY PF05495.7 KND99076.1 - 2.4e-17 62.8 14.0 3.5e-17 62.3 9.7 1.3 1 0 0 1 1 1 1 CHY zinc finger KRTAP7 PF15034.1 KND99076.1 - 0.077 13.6 2.0 0.17 12.5 1.3 1.6 1 1 0 1 1 1 0 KRTAP type 7 family Cytochrome_C7 PF14522.1 KND99076.1 - 0.21 11.2 8.4 0.34 10.5 5.8 1.4 1 0 0 1 1 1 0 Cytochrome c7 DZR PF12773.2 KND99076.1 - 2.4 8.0 8.8 20 5.0 6.1 2.5 1 1 0 1 1 1 0 Double zinc ribbon p450 PF00067.17 KND99077.1 - 2.3e-61 207.7 0.0 3.2e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cyclin_N PF00134.18 KND99078.1 - 1.8e-42 143.8 0.6 3.2e-42 143.0 0.4 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KND99078.1 - 4.1e-33 113.8 0.2 8.6e-33 112.7 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain MAM33 PF02330.11 KND99079.1 - 1.6e-20 73.7 8.4 2.2e-20 73.3 5.8 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF4355 PF14265.1 KND99079.1 - 0.023 14.6 0.2 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) DUF1889 PF08986.5 KND99079.1 - 0.084 13.0 0.0 0.51 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1889) RRM_1 PF00076.17 KND99080.1 - 4.4e-80 263.3 8.3 2.3e-19 68.7 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND99080.1 - 2.6e-69 229.1 2.6 2.8e-15 56.0 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND99080.1 - 1e-40 137.3 0.8 5.3e-09 35.7 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KND99080.1 - 7.4e-08 32.0 0.6 0.41 10.4 0.0 5.3 6 0 0 6 6 6 3 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KND99080.1 - 7.7e-05 22.3 0.3 0.15 11.8 0.0 3.5 2 1 1 3 3 3 2 Limkain b1 Toxin_ToxA PF11584.3 KND99080.1 - 0.11 12.2 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Proteinaceous host-selective toxin ToxA Acyltransferase PF01553.16 KND99081.1 - 0.0017 17.8 0.0 0.0047 16.3 0.0 1.8 1 1 0 1 1 1 1 Acyltransferase AAA_23 PF13476.1 KND99082.1 - 6.8e-25 88.5 0.1 6.8e-25 88.5 0.0 8.9 1 1 4 5 5 1 1 AAA domain SbcCD_C PF13558.1 KND99082.1 - 2.9e-10 39.9 0.0 1.1e-09 38.1 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 KND99082.1 - 1.5e-07 30.3 149.8 0.00021 19.9 18.7 7.2 2 1 3 6 6 6 4 AAA domain AAA_21 PF13304.1 KND99082.1 - 2.1e-05 24.6 3.8 0.0014 18.7 0.2 5.2 3 3 0 4 4 4 2 AAA domain SMC_N PF02463.14 KND99082.1 - 7e-05 22.1 0.0 7e-05 22.1 0.0 3.7 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KND99082.1 - 0.00017 20.7 3.9 0.00017 20.7 2.7 5.9 1 1 2 4 4 2 2 AAA ATPase domain Rad50_zn_hook PF04423.9 KND99082.1 - 0.00057 19.2 0.1 0.00057 19.2 0.1 5.8 5 0 0 5 5 5 1 Rad50 zinc hook motif DUF3584 PF12128.3 KND99082.1 - 0.00082 16.8 43.7 0.00082 16.8 30.3 6.0 2 1 4 6 6 5 2 Protein of unknown function (DUF3584) AAA_29 PF13555.1 KND99082.1 - 0.019 14.5 0.0 0.044 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3168 PF11367.3 KND99082.1 - 0.037 14.1 0.2 0.1 12.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3168) Kisspeptin PF15152.1 KND99082.1 - 0.26 12.0 1.6 0.68 10.6 0.0 2.6 2 0 0 2 2 2 0 Kisspeptin zf-H2C2_2 PF13465.1 KND99083.1 - 3.2e-22 77.6 30.0 2.9e-09 36.7 0.6 4.7 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 KND99083.1 - 1.4e-21 75.4 28.6 3.7e-06 26.9 0.3 4.9 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KND99083.1 - 7.4e-16 57.2 22.3 0.00037 20.6 0.3 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 KND99083.1 - 8.9e-05 22.5 16.4 0.00057 19.9 0.2 4.6 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KND99083.1 - 0.00067 19.7 6.3 0.029 14.4 0.5 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 KND99083.1 - 0.005 16.9 10.3 0.04 14.0 0.0 4.3 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KND99083.1 - 0.0058 16.4 16.5 0.018 14.9 0.5 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KND99083.1 - 0.009 15.6 10.0 0.049 13.3 0.1 3.3 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 KND99083.1 - 0.2 11.8 12.2 6.1 7.0 0.1 3.7 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) SID PF11778.3 KND99084.1 - 3.4e-10 39.9 0.6 8.1e-10 38.7 0.0 1.9 2 0 0 2 2 2 1 Septation initiation DUF972 PF06156.8 KND99084.1 - 0.013 15.8 3.7 0.025 14.9 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) COMP PF11598.3 KND99084.1 - 0.013 15.5 0.4 0.04 13.9 0.3 1.8 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein HR1 PF02185.11 KND99084.1 - 0.017 14.8 2.0 0.017 14.8 1.4 2.1 2 0 0 2 2 2 0 Hr1 repeat SpoIIIAH PF12685.2 KND99084.1 - 0.028 13.8 0.2 0.028 13.8 0.2 1.9 2 0 0 2 2 2 0 SpoIIIAH-like protein Rootletin PF15035.1 KND99084.1 - 0.09 12.7 2.6 0.087 12.8 0.4 1.9 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion RNA_pol_L_2 PF13656.1 KND99085.1 - 3.8e-31 106.3 0.1 5.4e-31 105.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KND99085.1 - 1.2e-14 53.1 0.0 1.5e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DEAD PF00270.24 KND99086.1 - 2.3e-45 154.1 0.0 2.3e-44 150.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND99086.1 - 7.9e-11 41.6 0.0 2.4e-10 40.1 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KND99086.1 - 0.00024 20.9 0.0 0.00056 19.8 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KND99086.1 - 0.0036 16.9 0.0 0.23 10.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KND99086.1 - 0.11 12.2 0.1 5.5 6.8 0.0 2.6 2 1 0 2 2 2 0 Part of AAA domain HLH PF00010.21 KND99088.1 - 2.5e-14 52.6 1.1 8.7e-14 50.9 0.8 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Bul1_C PF04426.7 KND99088.1 - 0.00046 19.4 5.3 0.00067 18.9 3.7 1.3 1 0 0 1 1 1 1 Bul1 C terminus SR-25 PF10500.4 KND99088.1 - 0.0024 17.4 10.2 0.003 17.0 7.1 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Neur_chan_memb PF02932.11 KND99088.1 - 0.38 10.6 2.4 0.45 10.3 1.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MRI PF15325.1 KND99088.1 - 0.51 11.3 3.2 0.76 10.7 2.2 1.3 1 0 0 1 1 1 0 Modulator of retrovirus infection Ndc1_Nup PF09531.5 KND99088.1 - 1.6 7.0 7.1 1.8 6.9 4.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LIP PF03583.9 KND99093.1 - 5.1e-100 334.4 0.2 9e-100 333.5 0.0 1.4 2 0 0 2 2 2 1 Secretory lipase Abhydrolase_6 PF12697.2 KND99093.1 - 5.6e-06 26.3 0.0 1.3e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND99093.1 - 2.1e-05 24.2 0.0 4.9e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KND99093.1 - 0.0079 15.4 0.5 0.84 8.8 0.0 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family Cutinase PF01083.17 KND99093.1 - 0.15 11.8 0.1 0.34 10.6 0.0 1.6 2 0 0 2 2 2 0 Cutinase LIP PF03583.9 KND99095.1 - 2.1e-98 329.0 0.0 3.1e-98 328.5 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 KND99095.1 - 2.6e-05 24.0 0.0 5.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND99095.1 - 0.00041 20.3 0.0 0.00096 19.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KND99095.1 - 0.0074 15.5 2.6 0.46 9.6 0.0 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family DUF530 PF04409.7 KND99097.1 - 0.027 12.5 0.3 0.035 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF530) LIP PF03583.9 KND99098.1 - 7.1e-89 297.8 0.1 9.5e-89 297.4 0.1 1.2 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 KND99098.1 - 1.9e-06 27.6 0.0 3.9e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KND99098.1 - 0.018 14.2 0.2 0.46 9.6 0.0 2.6 2 1 1 3 3 3 0 Prolyl oligopeptidase family LIP PF03583.9 KND99100.1 - 3.6e-99 331.6 0.0 4.5e-99 331.3 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 KND99100.1 - 2.7e-05 23.9 0.0 5.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KND99100.1 - 0.0038 17.1 0.0 0.0086 15.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KND99100.1 - 0.0059 15.8 1.2 0.66 9.1 0.0 2.5 2 1 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KND99100.1 - 0.13 11.7 0.0 0.39 10.1 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase LIP PF03583.9 KND99102.1 - 4.2e-90 301.8 0.0 5.5e-90 301.4 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 KND99102.1 - 4.5e-06 26.4 0.2 1e-05 25.3 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KND99102.1 - 0.011 14.9 2.2 0.49 9.5 0.0 2.7 2 1 1 3 3 3 0 Prolyl oligopeptidase family PH PF00169.24 KND99106.1 - 2.2e-08 34.2 0.1 8e-08 32.4 0.0 2.1 2 0 0 2 2 2 1 PH domain Peptidase_S68 PF10461.4 KND99108.1 - 0.049 13.3 0.1 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase S68 RNase_PH PF01138.16 KND99110.1 - 1.2e-28 100.0 0.0 1.7e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF2150 PF09920.4 KND99110.1 - 0.041 13.4 0.8 0.069 12.7 0.6 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) PEMT PF04191.8 KND99111.1 - 2.4e-57 191.5 13.1 9.1e-34 115.7 1.7 2.9 2 0 0 2 2 2 2 Phospholipid methyltransferase CALCOCO1 PF07888.6 KND99111.1 - 0.0022 16.3 0.6 0.0034 15.7 0.4 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like MFS_1 PF07690.11 KND99113.1 - 3e-25 88.6 40.5 2e-17 62.9 14.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND99113.1 - 1.3e-23 83.3 15.7 1.9e-23 82.7 10.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter zf-MIZ PF02891.15 KND99114.1 - 3.2e-10 39.3 0.8 9.4e-08 31.4 0.2 2.5 2 0 0 2 2 2 2 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KND99114.1 - 0.0077 15.7 1.1 0.014 14.8 0.1 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Chromosome_seg PF13889.1 KND99114.1 - 0.074 12.9 0.2 20 5.1 0.0 2.7 2 0 0 2 2 2 0 Chromosome segregation during meiosis Aldedh PF00171.17 KND99117.1 - 1.1e-150 502.0 0.0 1.2e-150 501.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cache_2 PF08269.6 KND99117.1 - 0.093 12.7 0.0 5.2 7.1 0.0 2.5 2 0 0 2 2 2 0 Cache domain DUF1487 PF07368.6 KND99117.1 - 0.15 11.2 0.1 1.9 7.6 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) zf-RING_2 PF13639.1 KND99119.1 - 1.8e-10 40.4 7.0 1.3e-09 37.7 4.9 2.3 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KND99119.1 - 6e-09 35.8 2.5 1.3e-08 34.8 1.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KND99119.1 - 6.2e-07 29.0 1.1 1.4e-06 27.8 0.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KND99119.1 - 9.2e-07 28.4 1.5 2.6e-06 26.9 1.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KND99119.1 - 2.8e-06 26.8 2.2 5.7e-06 25.8 1.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KND99119.1 - 3.2e-05 23.8 5.4 6.8e-05 22.8 1.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KND99119.1 - 0.0018 18.0 0.5 0.0041 16.9 0.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KND99119.1 - 0.24 11.1 2.0 0.84 9.4 1.4 2.0 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 KND99119.1 - 0.65 9.9 5.0 3.1 7.8 3.5 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 KND99119.1 - 0.76 9.4 3.4 1.1 8.8 0.2 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Seryl_tRNA_N PF02403.17 KND99121.1 - 1.3 9.0 4.7 0.34 10.9 0.7 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AF0941-like PF14591.1 KND99125.1 - 0.024 14.7 0.1 6.7 6.7 0.1 2.5 1 1 1 2 2 2 0 AF0941-like DXP_synthase_N PF13292.1 KND99125.1 - 0.072 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Complex1_LYR PF05347.10 KND99126.1 - 5.4e-08 32.5 0.0 1.2e-07 31.3 0.0 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KND99126.1 - 6.6e-07 29.4 0.0 1.5e-06 28.2 0.0 1.6 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KND99126.1 - 4.9e-06 26.9 0.0 7e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like GLTP PF08718.6 KND99127.1 - 6.5e-44 149.5 0.0 1.3e-43 148.6 0.0 1.4 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) DUF1798 PF08807.5 KND99127.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) Med10 PF09748.4 KND99130.1 - 1.5e-32 112.0 0.0 1.9e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Usp PF00582.21 KND99132.1 - 7.2e-05 23.0 0.0 0.00019 21.6 0.0 1.8 1 1 0 1 1 1 1 Universal stress protein family Mid1 PF12929.2 KND99133.1 - 9.4e-144 479.2 6.1 1.2e-143 478.9 4.2 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 KND99133.1 - 0.29 11.5 3.4 5.8 7.3 0.2 2.6 2 0 0 2 2 2 0 Fz domain Rep_fac_C PF08542.6 KND99136.1 - 5.1e-17 61.6 0.0 1.1e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KND99136.1 - 3.8e-11 42.9 0.2 3.8e-11 42.9 0.2 2.1 2 1 1 3 3 3 1 DNA polymerase III, delta subunit DNA_pol3_delta PF06144.8 KND99136.1 - 6.9e-07 28.9 0.2 1.3e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KND99136.1 - 2.3e-06 27.8 0.2 4.5e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 KND99136.1 - 0.0089 15.5 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KND99136.1 - 0.023 14.8 0.2 0.06 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain L27_1 PF09058.5 KND99136.1 - 0.055 13.3 1.5 0.46 10.4 0.0 2.9 3 0 0 3 3 3 0 L27_1 Prenyltransf PF01255.14 KND99136.1 - 0.13 11.3 1.9 6.1 5.9 1.3 2.1 1 1 0 1 1 1 0 Putative undecaprenyl diphosphate synthase PH PF00169.24 KND99137.1 - 2.4e-23 82.3 10.3 2.7e-13 50.0 3.6 2.1 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 KND99137.1 - 2.2e-11 43.9 16.3 2e-09 37.6 4.7 2.7 2 2 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 KND99137.1 - 2.2e-09 37.1 9.9 1.2e-06 28.3 1.4 2.6 2 1 0 2 2 2 2 PH domain PH_8 PF15409.1 KND99137.1 - 5.4e-07 29.5 9.1 2.7e-05 24.1 1.9 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 KND99137.1 - 0.00016 21.8 15.0 0.038 14.1 4.7 3.8 2 2 0 2 2 2 2 Pleckstrin homology domain Myosin_TH1 PF06017.8 KND99137.1 - 0.00047 19.5 1.0 0.18 11.0 0.1 2.3 2 0 0 2 2 2 2 Myosin tail Mcp5_PH PF12814.2 KND99137.1 - 0.0035 17.2 14.7 0.33 10.8 0.3 2.6 2 1 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology CagX PF03524.10 KND99137.1 - 0.013 14.7 1.5 0.3 10.3 0.5 2.5 1 1 1 2 2 2 0 Conjugal transfer protein PH_6 PF15406.1 KND99137.1 - 0.017 15.1 0.1 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain DUF3964 PF13107.1 KND99137.1 - 0.033 14.4 0.3 0.089 13.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3964) bPH_3 PF14470.1 KND99137.1 - 0.036 14.3 0.6 0.12 12.7 0.1 2.1 3 0 0 3 3 3 0 Bacterial PH domain PH_2 PF08458.5 KND99137.1 - 0.23 11.3 0.1 0.23 11.3 0.1 2.3 2 1 0 2 2 2 0 Plant pleckstrin homology-like region Smr PF01713.16 KND99138.1 - 2.7e-12 46.7 0.0 1.6e-11 44.2 0.0 2.2 2 0 0 2 2 2 1 Smr domain CUE PF02845.11 KND99138.1 - 3.3e-08 32.8 0.3 0.0002 20.7 0.0 2.7 2 0 0 2 2 2 2 CUE domain DUF615 PF04751.9 KND99138.1 - 0.048 13.3 0.5 0.11 12.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF615) Metal_resist PF13801.1 KND99138.1 - 0.79 9.7 3.0 0.38 10.7 0.2 1.8 2 0 0 2 2 2 0 Heavy-metal resistance Peptidase_M22 PF00814.20 KND99139.1 - 1.1e-83 280.7 0.0 1.4e-83 280.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Staygreen PF12638.2 KND99139.1 - 0.047 13.2 0.0 0.95 8.9 0.0 2.2 2 0 0 2 2 2 0 Staygreen protein DASH_Spc34 PF08657.5 KND99140.1 - 1.3e-25 90.5 0.0 2.3e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 DASH complex subunit Spc34 Prefoldin_2 PF01920.15 KND99140.1 - 0.0065 16.2 0.5 0.0065 16.2 0.3 2.3 3 0 0 3 3 3 1 Prefoldin subunit DUF948 PF06103.6 KND99140.1 - 0.0091 15.8 1.7 0.28 11.0 0.0 3.1 2 1 1 3 3 3 1 Bacterial protein of unknown function (DUF948) DUF2353 PF09789.4 KND99140.1 - 0.076 12.2 1.4 0.27 10.4 0.5 1.8 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Ribosomal_L7Ae PF01248.21 KND99141.1 - 1.1e-22 79.3 0.0 1.2e-22 79.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L24e PF01246.15 KND99143.1 - 7.3e-34 115.4 0.4 7.3e-34 115.4 0.3 2.1 2 1 0 2 2 2 1 Ribosomal protein L24e DUF4617 PF15395.1 KND99143.1 - 0.71 7.8 12.8 0.82 7.6 8.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4617) Asparaginase_2 PF01112.13 KND99144.1 - 3.1e-14 52.4 0.0 2.5e-13 49.4 0.0 1.9 1 1 0 1 1 1 1 Asparaginase HCO3_cotransp PF00955.16 KND99145.1 - 4.6e-61 207.0 12.3 3.4e-37 128.2 4.9 2.1 1 1 1 2 2 2 2 HCO3- transporter family La PF05383.12 KND99147.1 - 4.2e-16 58.4 0.1 9.1e-16 57.4 0.0 1.6 2 0 0 2 2 2 1 La domain Tim17 PF02466.14 KND99149.1 - 6.4e-21 74.7 0.1 1.2e-20 73.8 0.0 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family ABC2_membrane PF01061.19 KND99149.1 - 0.03 13.5 0.8 0.3 10.2 0.0 2.1 2 0 0 2 2 2 0 ABC-2 type transporter DCA16 PF15349.1 KND99149.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 Thioredoxin PF00085.15 KND99150.1 - 7e-53 176.6 0.6 1e-25 89.3 0.0 3.9 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 KND99150.1 - 2e-24 86.4 4.4 3.4e-19 69.3 1.3 2.8 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KND99150.1 - 6.2e-13 48.9 3.5 1.7e-05 24.9 0.0 4.2 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KND99150.1 - 1.1e-08 35.0 0.5 0.012 15.7 0.0 3.8 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KND99150.1 - 1.1e-08 34.9 0.3 0.00067 19.6 0.0 3.3 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_9 PF14595.1 KND99150.1 - 7.5e-05 22.3 0.3 0.072 12.6 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin AhpC-TSA PF00578.16 KND99150.1 - 0.00015 21.4 1.1 0.34 10.5 0.0 4.0 4 0 0 4 4 4 1 AhpC/TSA family Redoxin PF08534.5 KND99150.1 - 0.00016 21.2 0.3 0.04 13.4 0.0 3.4 3 1 1 4 4 4 1 Redoxin Thioredoxin_3 PF13192.1 KND99150.1 - 0.1 12.4 0.0 27 4.6 0.0 3.0 2 0 0 2 2 2 0 Thioredoxin domain WD40 PF00400.27 KND99151.1 - 9.1e-24 82.4 7.2 2.1e-06 27.3 0.1 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat RNA_polI_A14 PF08203.6 KND99151.1 - 0.13 12.5 0.1 0.89 9.8 0.0 2.5 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 FAM117 PF15388.1 KND99152.1 - 0.042 13.0 0.0 0.047 12.9 0.0 1.0 1 0 0 1 1 1 0 Protein Family FAM117 Fungal_trans PF04082.13 KND99155.1 - 9.8e-10 37.7 0.2 3.2e-09 36.0 0.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_1 PF00561.15 KND99157.1 - 3.2e-38 131.5 0.0 2.2e-37 128.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KND99157.1 - 2.4e-08 34.1 0.0 5.8e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND99157.1 - 0.038 13.7 0.0 0.24 11.1 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family Glyco_transf_28 PF03033.15 KND99158.1 - 1.1e-25 89.9 0.0 2.7e-25 88.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 KND99158.1 - 3.7e-23 80.8 0.2 1.7e-17 62.6 0.1 2.7 2 0 0 2 2 2 2 GRAM domain UDPGT PF00201.13 KND99158.1 - 7.2e-11 41.3 0.0 1.3e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.24 KND99158.1 - 1.4e-06 28.4 0.9 1.8e-05 24.8 0.0 3.4 4 1 0 4 4 4 1 PH domain Glyco_trans_1_3 PF13528.1 KND99158.1 - 0.019 14.1 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 ABC_membrane PF00664.18 KND99159.1 - 1.4e-49 168.9 1.7 1.7e-49 168.6 1.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KND99159.1 - 9.4e-34 116.6 0.0 1.9e-33 115.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KND99159.1 - 1.3e-06 27.8 0.0 0.00035 19.8 0.0 2.5 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KND99159.1 - 2.8e-06 27.4 0.4 2.7e-05 24.3 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 KND99159.1 - 3.6e-06 27.1 5.6 0.0025 17.8 0.2 2.8 2 1 0 3 3 2 2 AAA domain AAA_25 PF13481.1 KND99159.1 - 3.8e-06 26.4 0.0 0.069 12.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KND99159.1 - 2.2e-05 24.5 0.0 5.8e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KND99159.1 - 7.4e-05 23.5 0.0 0.0002 22.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA PF00004.24 KND99159.1 - 8.7e-05 22.7 0.4 0.0016 18.6 0.3 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KND99159.1 - 0.00034 20.1 0.0 0.11 11.8 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain AAA_29 PF13555.1 KND99159.1 - 0.00041 19.8 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KND99159.1 - 0.00045 20.5 0.0 0.0016 18.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KND99159.1 - 0.00079 19.1 0.0 0.01 15.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF258 PF03193.11 KND99159.1 - 0.0045 16.1 0.0 0.0084 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KND99159.1 - 0.0047 16.7 0.0 0.018 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KND99159.1 - 0.0053 16.1 0.1 0.28 10.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein SbcCD_C PF13558.1 KND99159.1 - 0.0075 16.1 0.7 0.034 14.0 0.5 2.0 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 KND99159.1 - 0.034 13.9 0.0 0.55 10.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_19 PF13245.1 KND99159.1 - 0.059 13.1 0.0 0.39 10.4 0.0 2.3 3 0 0 3 3 2 0 Part of AAA domain MobB PF03205.9 KND99159.1 - 0.078 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B LRR_4 PF12799.2 KND99160.1 - 2.1e-06 27.2 13.6 0.00026 20.5 0.9 4.0 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KND99160.1 - 8.8e-05 22.1 12.2 0.002 17.8 4.1 3.4 2 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KND99160.1 - 0.00069 19.3 13.6 2 8.7 0.2 5.8 5 0 0 5 5 5 3 Leucine Rich Repeat F-box PF00646.28 KND99160.1 - 0.02 14.5 0.9 0.052 13.2 0.6 1.8 1 0 0 1 1 1 0 F-box domain LRR_6 PF13516.1 KND99160.1 - 0.086 12.9 7.2 52 4.3 0.0 5.1 5 0 0 5 5 5 0 Leucine Rich repeat LRR_7 PF13504.1 KND99160.1 - 0.096 12.9 9.0 83 4.0 0.0 5.7 5 0 0 5 5 5 0 Leucine rich repeat SYF2 PF08231.7 KND99161.1 - 1.1e-08 35.3 27.1 4.1e-08 33.4 13.6 3.0 1 1 1 2 2 2 1 SYF2 splicing factor Methyltransf_3 PF01596.12 KND99162.1 - 3.6e-12 45.7 0.1 7.4e-12 44.7 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 KND99162.1 - 3.7e-10 40.5 0.0 6e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND99162.1 - 0.0053 17.3 0.0 0.017 15.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Syntaxin-18_N PF10496.4 KND99163.1 - 3e-15 55.8 0.2 3e-15 55.8 0.1 2.5 3 1 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 KND99163.1 - 0.0083 15.7 8.1 0.0083 15.7 5.6 1.9 1 1 1 2 2 2 1 SNARE domain OmpH PF03938.9 KND99163.1 - 0.56 10.1 12.6 3.9 7.3 8.7 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) GTP_EFTU PF00009.22 KND99164.1 - 4.9e-48 163.0 0.1 8.6e-48 162.2 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KND99164.1 - 9.4e-07 28.7 0.0 5e-06 26.4 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.12 KND99164.1 - 5.3e-06 26.5 0.1 1.7e-05 24.9 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain Miro PF08477.8 KND99164.1 - 0.00043 20.7 0.0 0.0017 18.8 0.0 2.0 1 1 0 1 1 1 1 Miro-like protein HBS1_N PF08938.5 KND99165.1 - 3e-15 56.0 2.6 3.4e-15 55.9 1.8 1.0 1 0 0 1 1 1 1 HBS1 N-terminus DUF1880 PF08976.6 KND99165.1 - 0.13 12.4 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1880) V-ATPase_H_N PF03224.9 KND99166.1 - 1e-37 129.9 8.4 1e-37 129.9 5.8 1.5 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 KND99166.1 - 1.4e-19 70.1 2.2 1.7e-18 66.6 0.0 2.7 2 1 1 3 3 3 1 V-ATPase subunit H UME PF08064.8 KND99166.1 - 0.035 14.0 0.3 0.31 11.0 0.0 2.5 2 1 1 3 3 3 0 UME (NUC010) domain BIR PF00653.16 KND99168.1 - 4.6e-29 100.6 4.5 8.9e-17 61.2 0.7 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain ZYG-11_interact PF05884.7 KND99168.1 - 0.75 8.8 0.7 1.6 7.7 0.2 1.7 2 0 0 2 2 2 0 Interactor of ZYG-11 SAPS PF04499.10 KND99170.1 - 1.7e-135 452.3 0.8 1.7e-135 452.3 0.6 2.0 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein DnaJ PF00226.26 KND99171.1 - 2.6e-16 59.1 0.3 4.9e-16 58.2 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Flu_B_M2 PF04772.7 KND99171.1 - 0.15 12.1 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) PTPLA PF04387.9 KND99172.1 - 5.8e-07 29.0 6.8 5.8e-07 29.0 4.7 2.1 2 1 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA ACT PF01842.20 KND99173.1 - 0.0082 15.6 0.3 0.018 14.5 0.0 1.7 2 0 0 2 2 2 1 ACT domain Ins_allergen_rp PF06757.8 KND99173.1 - 0.041 13.3 0.1 0.053 12.9 0.0 1.1 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification TENA_THI-4 PF03070.11 KND99174.1 - 5.5e-10 39.3 0.1 1.1e-09 38.3 0.1 1.4 1 1 0 1 1 1 1 TENA/THI-4/PQQC family MRP_L53 PF10780.4 KND99175.1 - 1.5e-13 50.4 0.0 2.3e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 NMO PF03060.10 KND99176.1 - 1.1e-57 195.6 0.0 1.3e-57 195.4 0.0 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KND99176.1 - 3.4e-06 26.1 2.5 0.00011 21.2 1.7 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KND99176.1 - 4.5e-05 22.4 2.1 0.0017 17.3 0.1 2.2 2 0 0 2 2 2 2 FMN-dependent dehydrogenase DHO_dh PF01180.16 KND99176.1 - 0.0014 17.6 0.1 0.011 14.7 0.0 2.1 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase ComA PF02679.10 KND99176.1 - 0.043 12.8 0.1 0.11 11.5 0.0 1.5 1 1 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) DUF1265 PF06887.9 KND99176.1 - 0.17 11.5 0.2 0.17 11.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1265) FAD_binding_6 PF00970.19 KND99177.1 - 1.4e-13 50.8 0.0 3.3e-13 49.5 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KND99177.1 - 3e-11 43.8 0.0 3e-09 37.4 0.0 2.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Globin PF00042.17 KND99177.1 - 2e-06 28.1 0.5 5.2e-06 26.7 0.0 2.0 2 1 0 2 2 2 1 Globin NAD_binding_6 PF08030.7 KND99177.1 - 0.0019 18.1 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain UFC1 PF08694.6 KND99177.1 - 0.041 13.3 0.1 0.073 12.5 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 D-ser_dehydrat PF14031.1 KND99178.1 - 5.2e-21 74.6 0.0 1e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 KND99178.1 - 4.6e-12 45.9 0.0 8.4e-12 45.1 0.0 1.4 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Fer2_3 PF13085.1 KND99180.1 - 1.9e-32 111.3 0.1 3.1e-32 110.6 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 KND99180.1 - 1.8e-10 41.0 8.0 1.8e-10 41.0 5.5 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 KND99180.1 - 9.3e-09 35.1 5.8 9.3e-09 35.1 4.0 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 KND99180.1 - 5.8e-05 23.4 2.9 5.8e-05 23.4 2.0 2.7 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 KND99180.1 - 0.00013 21.6 5.7 0.00013 21.6 3.9 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 KND99180.1 - 0.001 19.3 8.5 0.047 13.9 0.2 3.2 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 KND99180.1 - 0.0017 18.0 5.6 0.0031 17.2 1.2 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 KND99180.1 - 0.0021 18.3 5.9 0.0021 18.3 4.1 2.6 2 2 0 2 2 2 1 4Fe-4S dicluster domain NIF3 PF01784.13 KND99180.1 - 0.17 11.4 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) Fer4_15 PF13459.1 KND99180.1 - 3.8 8.1 8.5 2.5 8.7 0.2 2.7 3 0 0 3 3 2 0 4Fe-4S single cluster domain Fer4_16 PF13484.1 KND99180.1 - 9.4 7.0 12.7 9.7 7.0 0.3 3.3 3 1 0 3 3 3 0 4Fe-4S double cluster binding domain 2-Hacid_dh_C PF02826.14 KND99182.1 - 3.9e-40 136.9 0.0 1e-39 135.5 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KND99182.1 - 3.6e-17 62.0 0.0 4.8e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Tox-WTIP PF15654.1 KND99182.1 - 0.039 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Toxin with a conserved tryptophan and TIP tripeptide motif Zn_clus PF00172.13 KND99183.1 - 4.1e-05 23.3 8.8 8.4e-05 22.3 6.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND99183.1 - 0.00016 20.6 0.5 0.00053 18.9 0.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KND99185.1 - 1.8e-25 89.4 31.1 1.8e-25 89.4 21.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily ZYG-11_interact PF05884.7 KND99185.1 - 0.0021 17.2 1.0 0.004 16.2 0.7 1.4 1 0 0 1 1 1 1 Interactor of ZYG-11 NDT80_PhoG PF05224.7 KND99186.1 - 3.2e-17 63.1 0.6 3.2e-17 63.1 0.4 2.4 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Aminotran_1_2 PF00155.16 KND99187.1 - 7.6e-44 150.1 0.0 9e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KND99187.1 - 1.1e-07 30.9 0.0 4.2e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KND99187.1 - 1.3e-07 30.2 0.0 2e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 KND99187.1 - 2e-06 27.1 0.0 3.1e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Alliinase_C PF04864.8 KND99187.1 - 0.021 13.5 0.0 0.029 13.0 0.0 1.2 1 0 0 1 1 1 0 Allinase Aminotran_3 PF00202.16 KND99187.1 - 0.097 11.4 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-III Pkinase PF00069.20 KND99189.1 - 1.2e-65 221.2 0.0 2.2e-65 220.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND99189.1 - 2e-28 99.1 0.0 4.1e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KND99189.1 - 0.086 12.5 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.27 KND99190.1 - 5.5e-10 38.7 0.5 1.2e-05 25.0 0.1 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat EPL1 PF10513.4 KND99191.1 - 1.1e-32 113.5 9.2 1.1e-32 113.5 6.4 4.1 4 0 0 4 4 4 1 Enhancer of polycomb-like NAD_binding_10 PF13460.1 KND99192.1 - 3.1e-27 95.7 1.5 3.6e-27 95.5 1.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KND99192.1 - 5.8e-09 35.7 1.1 2.4e-08 33.7 0.7 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KND99192.1 - 2e-06 27.2 4.1 7.2e-06 25.4 2.8 1.7 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KND99192.1 - 5.3e-05 22.0 1.2 7.5e-05 21.5 0.8 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 KND99192.1 - 5.9e-05 22.2 1.0 7.6e-05 21.8 0.7 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KND99192.1 - 8e-05 22.9 0.2 0.00017 21.9 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 KND99192.1 - 0.00041 20.3 1.3 0.00064 19.6 0.9 1.4 1 0 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.15 KND99192.1 - 0.00087 19.2 0.8 0.0018 18.1 0.6 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 KND99192.1 - 0.0028 16.5 0.3 0.5 9.2 0.0 2.7 1 1 1 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 KND99192.1 - 0.0029 16.5 0.1 0.0083 15.0 0.1 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_Gly3P_dh_N PF01210.18 KND99192.1 - 0.0065 16.2 0.3 0.0084 15.8 0.2 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus KR PF08659.5 KND99192.1 - 0.021 14.4 0.8 0.035 13.7 0.4 1.5 1 1 0 1 1 1 0 KR domain ApbA PF02558.11 KND99192.1 - 0.043 13.2 0.2 0.071 12.5 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 KND99192.1 - 0.043 13.1 1.1 0.094 12.0 0.8 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ldh_1_N PF00056.18 KND99192.1 - 0.14 12.0 2.7 0.27 11.0 1.9 1.6 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain FTHFS PF01268.14 KND99193.1 - 7.6e-246 816.4 2.5 9.6e-246 816.1 1.8 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 KND99193.1 - 7.4e-68 226.6 1.3 3.5e-67 224.4 0.4 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KND99193.1 - 2.3e-32 111.4 0.9 2.2e-30 105.1 0.1 2.8 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain FH2 PF02181.18 KND99194.1 - 4.7e-65 219.8 13.0 4.7e-65 219.8 9.0 2.6 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 KND99194.1 - 4.9e-16 58.6 24.8 9.1e-16 57.7 5.4 4.5 3 1 0 3 3 3 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 KND99194.1 - 8.2e-13 48.1 4.1 8.2e-13 48.1 2.9 3.8 4 1 0 4 4 4 1 Diaphanous FH3 Domain SlyX PF04102.7 KND99194.1 - 2.9 8.3 10.5 0.27 11.6 0.1 4.6 4 0 0 4 4 4 0 SlyX PIF1 PF05970.9 KND99197.1 - 1.9e-51 175.1 0.5 5.3e-40 137.4 0.1 2.4 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 KND99197.1 - 2e-17 63.4 0.0 3.4e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 KND99197.1 - 4.3e-07 28.0 0.1 8.5e-06 23.8 0.0 2.1 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.1 KND99197.1 - 5.9e-07 29.6 0.0 1.6e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KND99197.1 - 3.3e-06 26.3 0.0 6.3e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 KND99197.1 - 2.2e-05 24.1 0.1 5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 KND99197.1 - 5.8e-05 23.1 0.0 0.0039 17.2 0.0 2.7 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 KND99197.1 - 0.00075 19.5 0.2 0.011 15.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 KND99197.1 - 0.0012 19.0 0.4 0.0028 17.8 0.1 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KND99197.1 - 0.0025 16.7 0.1 0.0045 15.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.11 KND99197.1 - 0.003 16.8 0.0 0.0081 15.4 0.0 1.7 1 0 0 1 1 1 1 PhoH-like protein AAA_17 PF13207.1 KND99197.1 - 0.0035 18.1 0.0 0.014 16.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KND99197.1 - 0.006 16.1 0.6 0.093 12.2 0.0 2.6 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.12 KND99197.1 - 0.022 14.1 0.2 0.5 9.7 0.0 2.4 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF87 PF01935.12 KND99197.1 - 0.023 14.5 2.2 0.048 13.4 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 UvrD-helicase PF00580.16 KND99197.1 - 0.024 13.9 0.0 0.024 13.9 0.0 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Sigma54_activ_2 PF14532.1 KND99197.1 - 0.026 14.5 0.2 0.084 12.9 0.0 1.9 2 1 0 2 2 1 0 Sigma-54 interaction domain MobB PF03205.9 KND99197.1 - 0.047 13.4 0.2 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KND99197.1 - 0.061 13.5 0.1 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 KND99197.1 - 0.069 13.4 0.1 0.26 11.5 0.0 2.1 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.21 KND99197.1 - 0.087 12.2 0.1 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 KND99197.1 - 0.11 11.9 0.1 0.39 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Fungal_trans PF04082.13 KND99200.1 - 3.7e-29 101.4 1.3 3.7e-29 101.4 0.9 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-RING_2 PF13639.1 KND99201.1 - 1.5e-06 27.8 8.5 3.3e-06 26.8 5.9 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 KND99201.1 - 7.4e-06 25.8 6.1 2.3e-05 24.2 4.2 1.8 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.2 KND99201.1 - 6.3e-05 23.0 5.6 0.00014 21.9 3.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KND99201.1 - 0.00048 19.9 2.9 0.0011 18.8 2.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 KND99201.1 - 0.0012 18.8 8.3 0.0024 17.8 5.8 1.6 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4 PF00097.20 KND99201.1 - 0.022 14.3 9.9 0.058 13.0 6.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4609 PF15382.1 KND99201.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4609) C1_1 PF00130.17 KND99201.1 - 0.69 9.6 6.8 1.8 8.3 4.7 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.6 KND99201.1 - 6.3 6.8 7.2 13 5.8 5.0 1.6 1 0 0 1 1 1 0 RING-like domain PTPA PF03095.10 KND99202.1 - 1.1e-103 346.4 0.0 1.4e-103 346.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein XPG_I PF00867.13 KND99203.1 - 2.5e-24 85.1 0.0 7.8e-24 83.5 0.0 1.9 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 KND99203.1 - 0.0004 19.9 0.0 0.00077 19.0 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing XPG_N PF00752.12 KND99203.1 - 0.006 16.8 0.0 0.017 15.3 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain Glyco_hydro_3 PF00933.16 KND99204.1 - 7.2e-46 156.5 0.0 1e-45 156.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PEPCK_ATP PF01293.15 KND99205.1 - 5.7e-219 727.4 0.0 6.6e-219 727.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_25 PF13481.1 KND99205.1 - 0.057 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KND99205.1 - 0.059 13.2 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KND99205.1 - 0.063 12.3 0.1 0.13 11.3 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.1 KND99205.1 - 0.12 11.9 0.5 0.27 10.8 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-C2HC PF01530.13 KND99206.1 - 0.4 10.4 2.3 1 9.1 1.6 1.7 1 0 0 1 1 1 0 Zinc finger, C2HC type p450 PF00067.17 KND99207.1 - 9.1e-63 212.3 0.0 1.1e-62 212.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3414 PF11894.3 KND99208.1 - 0 1209.6 55.4 0 1209.4 38.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) AA_permease PF00324.16 KND99211.1 - 4.9e-103 345.0 35.9 6e-103 344.7 24.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND99211.1 - 1.2e-24 86.7 36.5 1.5e-24 86.3 25.3 1.2 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 KND99211.1 - 0.21 11.2 4.5 2 8.1 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) DUF3487 PF11990.3 KND99211.1 - 0.26 10.6 0.1 0.26 10.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) PIN_4 PF13638.1 KND99212.1 - 2.8e-15 56.5 0.3 6.7e-15 55.3 0.2 1.7 1 0 0 1 1 1 1 PIN domain TPR_MLP1_2 PF07926.7 KND99213.1 - 5e-05 23.0 20.7 5e-05 23.0 14.4 16.1 4 3 11 15 15 15 5 TPR/MLP1/MLP2-like protein MFS_1 PF07690.11 KND99214.1 - 5.1e-38 130.6 29.4 5.1e-38 130.6 20.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KND99214.1 - 8.1e-08 31.2 35.1 5.4e-07 28.5 9.5 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter DUF2178 PF09946.4 KND99214.1 - 0.099 12.3 2.4 0.19 11.4 0.1 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2178) DAGK_cat PF00781.19 KND99215.1 - 6.8e-13 48.1 0.0 2.1e-12 46.6 0.0 1.9 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain XRN_N PF03159.13 KND99216.1 - 4.7e-106 353.4 0.0 1.2e-105 352.1 0.0 1.8 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Sugar_tr PF00083.19 KND99217.1 - 3.3e-79 266.5 26.0 4.3e-79 266.2 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND99217.1 - 3.5e-18 65.4 25.9 1.1e-16 60.5 15.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4342 PF14242.1 KND99217.1 - 0.035 13.8 0.9 0.11 12.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) P16-Arc PF04699.9 KND99217.1 - 0.077 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) ATG11 PF10377.4 KND99217.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 Autophagy-related protein 11 Cas_Cmr5 PF09701.5 KND99218.1 - 0.085 13.0 0.3 0.28 11.3 0.0 1.7 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Cmr5) Motilin_ghrelin PF04644.7 KND99218.1 - 0.27 11.0 3.8 0.4 10.5 2.6 1.2 1 0 0 1 1 1 0 Motilin/ghrelin PLU-1 PF08429.6 KND99220.1 - 1.2e-38 132.8 2.1 1.2e-38 132.8 1.4 2.2 2 0 0 2 2 2 1 PLU-1-like protein JmjC PF02373.17 KND99220.1 - 9.4e-21 74.1 0.4 3.6e-10 40.1 0.3 2.8 2 0 0 2 2 2 2 JmjC domain, hydroxylase ARID PF01388.16 KND99220.1 - 1.6e-16 59.8 0.0 6.9e-16 57.8 0.0 2.1 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 KND99220.1 - 2e-09 36.9 10.0 3.9e-09 36.0 7.0 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 KND99220.1 - 0.12 12.5 5.7 0.021 14.9 1.1 1.8 2 0 0 2 2 2 0 PHD-like zinc-binding domain Syntaxin_2 PF14523.1 KND99221.1 - 0.084 12.9 0.7 0.24 11.4 0.5 1.7 1 0 0 1 1 1 0 Syntaxin-like protein SlyX PF04102.7 KND99221.1 - 0.19 12.1 2.5 0.4 11.1 0.3 2.4 1 1 1 2 2 2 0 SlyX ARS2 PF04959.8 KND99221.1 - 1 9.5 3.5 0.61 10.2 0.1 2.1 2 1 0 2 2 2 0 Arsenite-resistance protein 2 His_kinase PF06580.8 KND99221.1 - 1.4 8.8 4.6 0.77 9.7 0.0 2.7 3 0 0 3 3 3 0 Histidine kinase AA_permease_2 PF13520.1 KND99222.1 - 7.1e-58 196.1 46.9 8.6e-58 195.8 32.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KND99222.1 - 1e-13 50.4 41.9 2.2e-13 49.3 29.0 1.5 1 1 0 1 1 1 1 Amino acid permease Peptidase_S10 PF00450.17 KND99223.1 - 6.2e-124 414.3 0.0 8.3e-124 413.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KND99223.1 - 0.00021 21.2 0.0 0.0013 18.6 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family COX14 PF14880.1 KND99225.1 - 1.1e-11 44.2 0.1 1.5e-11 43.7 0.1 1.4 1 1 0 1 1 1 1 Cytochrome oxidase c assembly Prefoldin PF02996.12 KND99226.1 - 1.6e-23 82.5 3.0 1.6e-23 82.5 2.1 1.3 1 1 0 1 1 1 1 Prefoldin subunit DUF2408 PF10303.4 KND99226.1 - 0.15 12.1 6.7 3.1 7.9 0.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2408) H-kinase_dim PF02895.9 KND99226.1 - 0.38 11.1 5.7 0.19 12.0 0.9 2.1 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain SYCE1 PF15233.1 KND99226.1 - 0.42 10.5 14.5 0.043 13.7 3.9 2.1 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 Toxin_52 PF15605.1 KND99226.1 - 0.65 9.9 3.7 2.2 8.2 0.2 2.3 2 1 0 2 2 2 0 Putative toxin 52 DUF1664 PF07889.7 KND99226.1 - 0.98 9.2 7.9 1.7 8.4 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4200 PF13863.1 KND99226.1 - 3.7 7.5 12.4 0.23 11.4 0.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) NPV_P10 PF05531.7 KND99226.1 - 8.9 6.6 8.9 1.7 8.9 0.7 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Rad10 PF03834.9 KND99227.1 - 4.5e-26 90.3 0.1 9.4e-26 89.3 0.1 1.6 1 1 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 KND99227.1 - 0.042 14.0 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF3812 PF12757.2 KND99227.1 - 0.097 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3812) HHH_6 PF14579.1 KND99227.1 - 0.11 12.5 0.2 0.66 10.0 0.0 2.2 2 1 0 2 2 2 0 Helix-hairpin-helix motif DUF1253 PF06862.7 KND99228.1 - 9.6e-162 538.3 7.0 1.4e-161 537.8 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) ICE2 PF08426.5 KND99229.1 - 3.3e-148 493.7 22.6 3.9e-148 493.4 15.6 1.0 1 0 0 1 1 1 1 ICE2 DUF1776 PF08643.5 KND99231.1 - 8.6e-86 287.7 0.0 1.5e-85 286.9 0.0 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) OPT PF03169.10 KND99232.1 - 1e-141 473.4 44.9 1.2e-141 473.2 31.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Gln-synt_C PF00120.19 KND99234.1 - 1.1e-64 218.0 0.0 1.3e-64 217.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KND99234.1 - 1.6e-21 75.6 0.0 2.5e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain ERAP1_C PF11838.3 KND99237.1 - 0.022 14.0 0.0 0.029 13.6 0.0 1.1 1 0 0 1 1 1 0 ERAP1-like C-terminal domain OPT PF03169.10 KND99239.1 - 3.3e-173 577.4 47.2 3.8e-173 577.2 32.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1687 PF07955.6 KND99241.1 - 1.5e-34 118.8 0.1 1.8e-34 118.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) SplA PF11132.3 KND99241.1 - 0.041 13.6 0.1 0.08 12.6 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator protein (SplA) DSPc PF00782.15 KND99243.1 - 3.8e-27 94.4 0.0 1.4e-26 92.5 0.0 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 KND99243.1 - 0.017 14.0 0.0 0.021 13.7 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 KND99243.1 - 0.048 12.9 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ank PF00023.25 KND99244.1 - 3.2e-36 121.3 2.1 2.1e-10 39.8 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 KND99244.1 - 7.1e-36 122.4 2.4 2e-15 56.9 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KND99244.1 - 6.8e-30 100.1 0.3 7.7e-08 31.8 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 KND99244.1 - 7.2e-29 99.6 3.9 3.6e-11 43.2 0.0 4.8 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KND99244.1 - 2.5e-28 97.4 2.4 6.6e-08 32.5 0.0 5.4 2 2 3 5 5 5 5 Ankyrin repeats (many copies) DUF2011 PF09428.5 KND99245.1 - 2.6e-25 88.8 16.2 3e-25 88.5 11.2 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) COG5 PF10392.4 KND99246.1 - 2.9e-37 127.5 1.3 2.9e-37 127.5 0.9 1.7 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Sec8_exocyst PF04048.9 KND99246.1 - 0.02 14.5 0.3 0.02 14.5 0.2 1.8 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Sec23_trunk PF04811.10 KND99247.1 - 1.2e-62 211.4 0.0 2.1e-62 210.6 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KND99247.1 - 1e-19 69.8 0.0 2.8e-19 68.4 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KND99247.1 - 3.7e-18 65.8 0.0 8.2e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KND99247.1 - 3e-17 61.8 5.8 5.5e-17 61.0 4.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KND99247.1 - 0.06 13.0 0.0 0.23 11.1 0.0 2.1 1 0 0 1 1 1 0 Gelsolin repeat Peptidase_M48 PF01435.13 KND99249.1 - 3.7e-42 144.4 0.0 5.2e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 GtrA PF04138.9 KND99249.1 - 0.00031 20.6 11.4 0.00031 20.6 7.9 2.0 2 0 0 2 2 2 1 GtrA-like protein Peptidase_S8 PF00082.17 KND99250.1 - 4.2e-36 124.5 2.7 6.5e-36 123.9 1.9 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KND99250.1 - 2.5e-09 37.5 0.0 5.1e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.17 KND99251.1 - 1.2e-35 123.0 5.2 1.7e-35 122.5 3.6 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KND99251.1 - 9.8e-13 48.4 0.0 1.9e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 G6PD_C PF02781.11 KND99253.1 - 3.5e-129 429.8 0.0 4.5e-129 429.4 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KND99253.1 - 4e-64 216.2 0.1 7.5e-64 215.3 0.1 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Peptidase_S8 PF00082.17 KND99254.1 - 1.9e-57 194.5 3.7 1.9e-57 194.5 2.6 1.7 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.15 KND99254.1 - 5.6e-25 86.9 0.6 1.8e-24 85.3 0.4 1.9 1 0 0 1 1 1 1 Proprotein convertase P-domain Mucin PF01456.12 KND99254.1 - 0.33 10.7 20.8 0.82 9.4 14.4 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Ndc1_Nup PF09531.5 KND99254.1 - 9 4.5 6.8 14 3.9 4.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Fe_hyd_lg_C PF02906.9 KND99256.1 - 3.7e-71 239.7 0.0 5.6e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Ytp1 PF10355.4 KND99258.1 - 2.3e-83 279.5 12.2 3.3e-83 279.0 8.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) Thioredoxin PF00085.15 KND99259.1 - 1.8e-09 37.1 0.0 4e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KND99259.1 - 0.0019 18.3 0.0 0.0047 17.0 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 KND99259.1 - 0.094 12.4 0.1 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family OPT PF03169.10 KND99263.1 - 5.8e-169 563.4 42.9 6.6e-169 563.2 29.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.10 KND99264.1 - 1.7e-177 591.6 44.3 1.9e-177 591.4 30.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Ribosomal_L22 PF00237.14 KND99264.1 - 0.27 11.2 0.0 0.56 10.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e PTPLA PF04387.9 KND99265.1 - 4.5e-41 140.0 12.6 1.4e-40 138.4 8.7 1.7 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA PTPLA PF04387.9 KND99266.1 - 5.5e-49 165.7 9.9 8.3e-49 165.1 6.9 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA ChAPs PF09295.5 KND99267.1 - 1.7e-24 86.3 0.0 5.2e-17 61.6 0.0 2.4 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 KND99267.1 - 0.00011 22.5 0.0 0.00019 21.7 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 KND99267.1 - 0.0071 15.9 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 KND99267.1 - 0.0076 16.3 0.1 0.018 15.1 0.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 KND99267.1 - 0.014 15.0 0.2 0.028 14.0 0.1 1.4 1 0 0 1 1 1 0 TPR repeat CEP44 PF15007.1 KND99267.1 - 0.067 12.9 0.5 0.15 11.7 0.3 1.5 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 LRR_4 PF12799.2 KND99268.1 - 3.2e-51 170.2 82.1 5.5e-08 32.2 1.1 12.8 7 4 4 13 13 13 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KND99268.1 - 1.7e-46 155.7 70.8 1.6e-09 37.4 3.2 10.0 4 3 4 9 9 9 9 Leucine rich repeat PP2C PF00481.16 KND99268.1 - 1.6e-37 129.2 0.0 3.2e-37 128.2 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C Guanylate_cyc PF00211.15 KND99268.1 - 8.8e-30 103.4 0.0 3.3e-29 101.5 0.0 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 KND99268.1 - 9.7e-21 70.6 75.3 0.1 12.6 0.0 19.5 20 1 0 20 20 20 10 Leucine Rich Repeat RA PF00788.18 KND99268.1 - 5.9e-10 39.4 0.0 1.2e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_6 PF13516.1 KND99268.1 - 8.1e-06 25.3 68.4 1.2 9.3 0.3 17.7 18 2 2 20 20 19 4 Leucine Rich repeat LRR_7 PF13504.1 KND99268.1 - 6.7e-05 22.4 63.4 1.5 9.3 0.2 16.6 18 0 0 18 18 17 3 Leucine rich repeat LRR_5 PF13306.1 KND99268.1 - 0.019 14.6 11.3 0.25 11.0 0.7 3.9 3 1 1 4 4 4 0 Leucine rich repeats (6 copies) PP2C_2 PF13672.1 KND99268.1 - 0.022 14.1 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C LRR_9 PF14580.1 KND99268.1 - 0.67 9.4 19.5 0.11 12.0 1.2 4.4 2 1 3 5 5 5 0 Leucine-rich repeat AA_permease PF00324.16 KND99269.1 - 2e-64 217.6 43.5 2.5e-64 217.3 30.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND99269.1 - 5.4e-15 54.8 48.5 6.6e-15 54.5 33.6 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_M50 PF02163.17 KND99269.1 - 0.17 10.8 2.4 0.59 9.0 0.9 2.5 1 1 1 2 2 2 0 Peptidase family M50 OPT PF03169.10 KND99270.1 - 1.3e-183 611.8 42.3 1.5e-183 611.6 29.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.10 KND99272.1 - 1.3e-171 572.2 46.8 1.5e-171 572.0 32.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein RseC_MucC PF04246.7 KND99272.1 - 2 7.9 5.1 15 5.1 0.0 3.5 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Arrestin_N PF00339.24 KND99273.1 - 2.6e-12 46.7 0.0 8.9e-11 41.8 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KND99273.1 - 0.0012 18.9 0.0 0.14 12.3 0.0 2.7 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain DUF3641 PF12345.3 KND99273.1 - 0.11 12.3 0.4 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3641) Arrestin_N PF00339.24 KND99274.1 - 1.3e-06 28.3 0.0 3.3e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KND99274.1 - 0.0024 17.9 1.1 0.087 12.9 0.3 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain ROF PF07073.7 KND99274.1 - 0.034 14.1 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 Modulator of Rho-dependent transcription termination (ROF) Glyco_hydro_32N PF00251.15 KND99275.1 - 3.4e-86 289.3 3.5 5.3e-86 288.7 2.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KND99275.1 - 2.3e-09 37.4 1.0 6.3e-09 36.0 0.4 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal MFS_1 PF07690.11 KND99276.1 - 1.1e-18 67.1 21.5 1.6e-18 66.5 14.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KND99276.1 - 9e-06 25.3 1.7 9e-06 25.3 1.2 2.2 2 0 0 2 2 2 1 MFS_1 like family V_ATPase_I PF01496.14 KND99276.1 - 0.07 10.9 0.2 0.13 10.0 0.1 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family B12D PF06522.6 KND99276.1 - 0.08 12.6 0.1 0.56 9.9 0.0 2.5 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF788 PF05620.6 KND99276.1 - 0.37 10.6 3.9 1.2 9.0 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF788) Glyco_hydro_81 PF03639.8 KND99277.1 - 2.3e-192 640.7 0.1 2.8e-192 640.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Arginase PF00491.16 KND99279.1 - 1.6e-85 286.7 0.0 2e-85 286.4 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KND99279.1 - 0.034 14.3 0.6 0.061 13.5 0.4 1.4 1 0 0 1 1 1 0 UPF0489 domain Arm PF00514.18 KND99281.1 - 2e-85 278.0 14.5 3.5e-12 45.6 0.0 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KND99281.1 - 8.4e-21 74.0 0.2 2.1e-05 24.6 0.0 5.0 1 1 4 5 5 5 5 HEAT repeats HEAT_EZ PF13513.1 KND99281.1 - 3.4e-19 68.7 0.5 7e-06 26.3 0.0 4.8 4 0 0 4 4 4 3 HEAT-like repeat IBB PF01749.15 KND99281.1 - 6.2e-19 67.9 3.9 1.3e-18 66.9 2.7 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 KND99281.1 - 1.7e-12 46.2 0.8 0.015 15.3 0.0 6.7 7 0 0 7 7 7 3 HEAT repeat Arm_2 PF04826.8 KND99281.1 - 2.6e-07 30.0 0.1 0.049 12.7 0.0 4.1 1 1 3 5 5 5 3 Armadillo-like Adaptin_N PF01602.15 KND99281.1 - 6.5e-05 21.4 0.1 0.0058 15.0 0.0 2.5 1 1 0 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 KND99281.1 - 0.00011 22.1 0.1 0.89 9.4 0.0 4.1 3 2 1 4 4 4 1 V-ATPase subunit H RICTOR_V PF14668.1 KND99281.1 - 0.00031 20.6 4.4 0.75 9.7 0.1 5.0 3 3 3 6 6 6 2 Rapamycin-insensitive companion of mTOR, domain 5 Proteasom_PSMB PF10508.4 KND99281.1 - 0.013 13.8 0.1 0.037 12.2 0.1 1.9 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit Usp PF00582.21 KND99283.1 - 2.4e-08 34.2 0.0 5.2e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Universal stress protein family ADK PF00406.17 KND99283.1 - 0.06 13.2 0.2 0.1 12.4 0.2 1.3 1 0 0 1 1 1 0 Adenylate kinase Peptidase_M14 PF00246.19 KND99284.1 - 1.2e-61 208.8 0.3 1.9e-61 208.1 0.0 1.4 2 0 0 2 2 2 1 Zinc carboxypeptidase DUF2573 PF10835.3 KND99284.1 - 0.0073 16.3 0.0 5.5 7.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2573) Aldo_ket_red PF00248.16 KND99287.1 - 8.6e-49 165.8 0.1 1e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Ras PF00071.17 KND99288.1 - 2.1e-47 160.5 0.0 4.4e-47 159.4 0.0 1.5 1 1 1 2 2 2 1 Ras family Miro PF08477.8 KND99288.1 - 3e-15 56.7 0.0 5.5e-15 55.9 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KND99288.1 - 3.6e-12 45.8 0.0 4.6e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KND99288.1 - 1.9e-07 30.4 0.0 2.3e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KND99288.1 - 2.7e-06 27.2 0.0 5.2e-06 26.4 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KND99288.1 - 1.8e-05 24.5 0.0 0.00031 20.5 0.0 2.1 2 0 0 2 2 2 1 Dynamin family SRPRB PF09439.5 KND99288.1 - 0.00021 20.5 0.0 0.00034 19.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KND99288.1 - 0.00053 19.4 0.0 0.023 14.1 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KND99288.1 - 0.0016 17.7 0.0 0.07 12.4 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KND99288.1 - 0.0056 15.8 0.0 0.0079 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KND99288.1 - 0.048 13.6 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 KND99288.1 - 0.092 12.6 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KND99288.1 - 0.11 11.9 0.1 0.67 9.4 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PAP_assoc PF03828.14 KND99289.1 - 2.4e-13 49.7 0.0 5.9e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KND99289.1 - 3e-13 49.8 0.4 4e-12 46.2 0.0 2.5 2 0 0 2 2 2 1 Nucleotidyltransferase domain TLP-20 PF06088.6 KND99289.1 - 0.071 12.7 0.2 0.071 12.7 0.1 2.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Pkinase PF00069.20 KND99290.1 - 2.2e-26 92.5 0.0 4.6e-25 88.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND99290.1 - 1.4e-13 50.5 0.0 8.8e-12 44.6 0.0 3.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KND99290.1 - 0.081 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF35_N PF12172.3 KND99290.1 - 0.36 10.7 2.1 0.7 9.8 1.4 1.4 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Rif1_N PF12231.3 KND99291.1 - 8.7e-32 110.4 5.4 3.3e-31 108.5 3.7 2.0 1 1 0 1 1 1 1 Rap1-interacting factor 1 N terminal RF-1 PF00472.15 KND99294.1 - 3e-14 52.8 0.1 5.6e-14 51.9 0.1 1.4 1 1 0 1 1 1 1 RF-1 domain D5_N PF08706.6 KND99294.1 - 0.036 14.1 2.4 0.062 13.3 1.7 1.3 1 0 0 1 1 1 0 D5 N terminal like Redoxin PF08534.5 KND99295.1 - 4.9e-31 107.2 0.0 5.8e-31 107.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KND99295.1 - 6.7e-10 38.7 0.0 8.5e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DCP1 PF06058.8 KND99296.1 - 2.5e-17 63.0 0.1 1.7e-10 40.9 0.0 2.6 2 1 0 2 2 2 2 Dcp1-like decapping family Spt20 PF12090.3 KND99297.1 - 3.6e-48 163.3 1.9 3.6e-48 163.3 1.3 6.7 4 2 0 4 4 4 1 Spt20 family FHA PF00498.21 KND99298.1 - 5e-14 52.1 0.1 9.6e-14 51.2 0.1 1.5 1 0 0 1 1 1 1 FHA domain PhyH PF05721.8 KND99299.1 - 1.1e-42 146.4 0.0 1.3e-42 146.2 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 KND99299.1 - 0.033 14.4 0.1 0.095 13.0 0.0 1.8 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Transp_cyt_pur PF02133.10 KND99300.1 - 4.6e-13 48.5 46.5 1.2e-12 47.1 32.3 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3043 PF11241.3 KND99300.1 - 4.4 6.8 5.8 6.6 6.2 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) SCO1-SenC PF02630.9 KND99301.1 - 2.4e-64 216.1 0.0 3.7e-64 215.5 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 KND99301.1 - 6.3e-05 22.6 0.0 9.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 KND99301.1 - 0.0011 19.0 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like ChlamPMP_M PF07548.6 KND99301.1 - 0.054 13.2 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain SET PF00856.23 KND99303.1 - 2.9e-05 24.4 0.0 6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 SET domain DUF2735 PF10931.3 KND99304.1 - 0.15 12.3 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2735) Pho88 PF10032.4 KND99305.1 - 9.4e-77 256.5 0.0 1e-76 256.4 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) SNase PF00565.12 KND99306.1 - 4.3e-40 136.3 0.0 3.1e-10 40.2 0.0 5.8 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 KND99306.1 - 1.3e-13 50.8 0.0 5.9e-13 48.7 0.0 2.1 2 0 0 2 2 2 1 Tudor domain LBR_tudor PF09465.5 KND99306.1 - 0.041 13.5 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain UQ_con PF00179.21 KND99307.1 - 6.9e-50 168.1 0.0 7.8e-50 167.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KND99307.1 - 0.24 11.2 1.1 0.3 11.0 0.8 1.5 1 1 0 1 1 1 0 RWD domain Amino_oxidase PF01593.19 KND99308.1 - 1e-64 219.2 0.0 1.3e-64 218.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KND99308.1 - 2.3e-12 46.7 0.0 5.5e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KND99308.1 - 1.8e-07 31.4 0.0 0.00012 22.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KND99308.1 - 0.00059 18.8 0.1 0.0041 16.0 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KND99308.1 - 0.00072 19.3 0.1 0.1 12.3 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 KND99308.1 - 0.0057 15.1 0.1 0.61 8.4 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Strep_67kDa_ant PF06100.6 KND99308.1 - 0.016 13.6 0.1 0.029 12.7 0.0 1.3 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Pyr_redox PF00070.22 KND99308.1 - 0.034 14.5 0.1 0.096 13.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KND99308.1 - 0.07 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 KND99308.1 - 0.15 11.1 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Polysacc_synt_4 PF04669.8 KND99309.1 - 6.8e-24 84.2 3.0 4.6e-23 81.5 2.1 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis Striatin PF08232.7 KND99310.1 - 2.5e-20 73.1 3.3 1.1e-19 71.0 0.6 2.7 2 1 0 2 2 2 1 Striatin family Coatomer_WDAD PF04053.9 KND99310.1 - 0.0016 17.3 0.1 0.0028 16.5 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region Sir1 PF11603.3 KND99310.1 - 0.02 15.0 0.1 0.072 13.2 0.0 1.9 2 0 0 2 2 2 0 Regulatory protein Sir1 TPD52 PF04201.10 KND99310.1 - 0.56 9.9 4.5 0.25 11.0 0.6 2.2 2 0 0 2 2 2 0 Tumour protein D52 family ALIX_LYPXL_bnd PF13949.1 KND99310.1 - 1.4 7.7 7.6 0.48 9.3 0.4 2.5 3 0 0 3 3 3 0 ALIX V-shaped domain binding to HIV ABC_tran PF00005.22 KND99311.1 - 1.5e-51 174.3 0.1 8.4e-27 94.1 0.0 5.4 4 2 0 4 4 3 2 ABC transporter AAA_21 PF13304.1 KND99311.1 - 3.2e-15 56.8 2.2 2.5e-06 27.6 0.1 4.3 4 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 KND99311.1 - 6.3e-11 41.9 0.0 0.0086 15.3 0.0 4.4 3 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KND99311.1 - 2.9e-08 33.0 0.2 0.0078 15.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Chromo PF00385.19 KND99311.1 - 1.4e-07 31.0 0.7 3.5e-07 29.8 0.5 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_17 PF13207.1 KND99311.1 - 2.4e-07 31.6 0.0 0.011 16.5 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KND99311.1 - 6.7e-07 28.6 0.2 0.082 11.9 0.0 3.9 3 1 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.18 KND99311.1 - 8.8e-07 28.8 0.0 0.012 15.5 0.0 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 KND99311.1 - 1.7e-06 27.2 0.0 0.0088 15.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KND99311.1 - 2.6e-06 27.8 13.4 0.00096 19.5 0.0 4.1 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 KND99311.1 - 1.1e-05 25.6 0.2 0.41 10.7 0.0 3.8 4 0 0 4 4 3 2 AAA domain Miro PF08477.8 KND99311.1 - 5.9e-05 23.5 0.0 0.073 13.5 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 KND99311.1 - 6.3e-05 21.8 0.3 0.18 10.5 0.0 2.4 2 0 0 2 2 2 2 ArgK protein AAA_28 PF13521.1 KND99311.1 - 0.00013 21.9 0.0 0.16 11.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 KND99311.1 - 0.00031 20.6 0.0 0.23 11.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KND99311.1 - 0.00031 21.0 2.8 0.066 13.5 0.0 3.9 4 0 0 4 4 4 1 AAA domain Zeta_toxin PF06414.7 KND99311.1 - 0.00032 19.8 0.3 0.69 8.9 0.0 3.6 3 0 0 3 3 3 1 Zeta toxin AAA_10 PF12846.2 KND99311.1 - 0.00032 20.2 2.4 0.25 10.7 0.0 3.6 5 0 0 5 5 3 2 AAA-like domain MobB PF03205.9 KND99311.1 - 0.00035 20.2 0.1 0.045 13.4 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B HEAT_2 PF13646.1 KND99311.1 - 0.00058 20.0 1.6 2.7 8.3 0.0 3.6 3 0 0 3 3 3 2 HEAT repeats RNA_helicase PF00910.17 KND99311.1 - 0.001 19.1 0.0 1.4 9.1 0.0 2.8 2 0 0 2 2 2 1 RNA helicase Dynamin_N PF00350.18 KND99311.1 - 0.0019 18.0 0.7 0.16 11.7 0.0 3.4 3 0 0 3 3 3 1 Dynamin family DUF87 PF01935.12 KND99311.1 - 0.002 18.0 7.3 0.073 12.8 0.1 4.6 4 1 1 5 5 4 1 Domain of unknown function DUF87 AAA PF00004.24 KND99311.1 - 0.0025 18.0 0.4 2 8.5 0.0 3.8 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KND99311.1 - 0.0026 17.7 0.2 1.4 8.9 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.7 KND99311.1 - 0.0047 16.5 0.2 2.8 7.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain SbcCD_C PF13558.1 KND99311.1 - 0.0056 16.5 0.0 4 7.4 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 KND99311.1 - 0.0094 15.5 0.1 4.8 6.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KND99311.1 - 0.014 15.3 0.4 0.83 9.5 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.1 KND99311.1 - 0.014 14.7 0.0 6.1 6.2 0.0 2.8 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.8 KND99311.1 - 0.022 13.6 0.2 2.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.10 KND99311.1 - 0.024 14.3 0.3 3.8 7.2 0.1 3.0 2 1 0 2 2 2 0 NTPase cobW PF02492.14 KND99311.1 - 0.035 13.5 0.6 11 5.3 0.0 3.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KND99311.1 - 0.041 13.3 0.1 5.7 6.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MutS_V PF00488.16 KND99311.1 - 0.055 12.8 0.1 5.7 6.2 0.0 2.3 2 0 0 2 2 2 0 MutS domain V ABC_ATPase PF09818.4 KND99311.1 - 0.055 12.0 0.5 2.5 6.5 0.0 3.1 2 1 0 2 2 2 0 Predicted ATPase of the ABC class Vac14_Fab1_bd PF12755.2 KND99311.1 - 0.067 13.5 0.5 0.25 11.7 0.1 2.2 2 0 0 2 2 1 0 Vacuolar 14 Fab1-binding region FtsK_SpoIIIE PF01580.13 KND99311.1 - 0.11 11.9 0.3 7.5 5.9 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_13 PF13166.1 KND99311.1 - 1.9 6.8 9.2 1.5 7.1 0.0 3.1 4 0 0 4 4 4 0 AAA domain Proteasome PF00227.21 KND99312.1 - 4.7e-41 140.1 0.0 5.4e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Utp14 PF04615.8 KND99313.1 - 1.9e-171 571.8 88.6 1.9e-171 571.8 61.4 2.8 1 1 1 2 2 2 1 Utp14 protein ALO PF04030.9 KND99314.1 - 5.6e-103 344.0 0.2 1.8e-102 342.4 0.0 1.9 3 0 0 3 3 3 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 KND99314.1 - 5.5e-24 84.2 0.0 7.9e-24 83.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DUF3936 PF13072.1 KND99314.1 - 0.01 15.2 0.3 0.034 13.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3936) HMG_CoA_synt_C PF08540.5 KND99317.1 - 5.5e-101 337.7 3.8 6.9e-101 337.4 2.7 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KND99317.1 - 8.4e-91 302.1 0.3 1.6e-90 301.3 0.2 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Tubulin_C PF03953.12 KND99320.1 - 1.8e-25 89.4 0.0 2.3e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin C-terminal domain TALPID3 PF15324.1 KND99322.1 - 0.23 8.7 2.5 0.24 8.7 1.8 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Herpes_UL56 PF04534.7 KND99322.1 - 0.45 10.2 1.7 0.8 9.3 1.2 1.5 1 1 0 1 1 1 0 Herpesvirus UL56 protein DUF320 PF03777.8 KND99322.1 - 1.3 8.8 5.5 1.3e+02 2.4 3.8 2.6 1 1 0 1 1 1 0 Small secreted domain (DUF320) DUF2045 PF09741.4 KND99323.1 - 0.11 11.5 0.1 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2045) NAD_binding_1 PF00175.16 KND99327.1 - 1.1e-25 90.2 0.0 2e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KND99327.1 - 1e-23 83.3 0.0 1.6e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KND99327.1 - 2.5e-05 24.2 0.0 0.00041 20.2 0.0 2.1 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Anoctamin PF04547.7 KND99327.1 - 0.058 12.0 0.0 0.073 11.7 0.0 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Aldo_ket_red PF00248.16 KND99328.1 - 2.4e-37 128.2 0.0 3.2e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family zf-CCCH PF00642.19 KND99329.1 - 5e-11 42.0 9.3 2.5e-06 26.9 0.6 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 KND99329.1 - 0.0025 17.6 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cation_efflux PF01545.16 KND99330.1 - 7.3e-46 156.5 7.1 1.1e-45 155.8 5.0 1.3 1 1 0 1 1 1 1 Cation efflux family DUF1129 PF06570.6 KND99330.1 - 0.12 11.6 0.4 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF2946 PF11162.3 KND99330.1 - 1.1 9.4 9.5 4.5 7.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) CLU PF13236.1 KND99331.1 - 4.1e-75 251.9 0.0 8.9e-75 250.9 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 KND99331.1 - 9.5e-42 142.7 0.7 1.1e-39 136.1 0.0 3.8 2 1 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 KND99331.1 - 5.1e-20 71.1 1.6 2.2e-08 33.9 0.0 3.5 1 1 3 4 4 4 4 Tetratricopeptide repeat CLU_N PF15044.1 KND99331.1 - 1.6e-14 53.7 0.1 6.3e-14 51.8 0.1 2.1 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.1 KND99331.1 - 2.5e-06 27.2 0.0 1.9 8.5 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KND99331.1 - 1.9e-05 24.2 0.1 1.3 8.7 0.0 3.8 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 KND99331.1 - 0.00085 19.0 1.1 1 9.4 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF727 PF05303.7 KND99331.1 - 0.0099 15.6 0.0 0.049 13.4 0.0 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_19 PF14559.1 KND99331.1 - 0.014 15.6 0.2 1 9.7 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KND99331.1 - 0.068 13.8 0.1 29 5.6 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat RP-C_C PF11800.3 KND99331.1 - 1.8 8.1 9.3 2.1 7.9 1.9 3.0 3 0 0 3 3 3 0 Replication protein C C-terminal region F-box-like PF12937.2 KND99332.1 - 1e-09 37.9 0.2 2.4e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KND99332.1 - 5.4e-08 32.3 0.3 1.1e-07 31.3 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 KND99332.1 - 0.11 12.2 0.0 0.38 10.4 0.0 1.9 2 0 0 2 2 2 0 F-box-like domain UIM PF02809.15 KND99332.1 - 0.36 10.5 12.4 0.043 13.4 1.4 3.3 3 0 0 3 3 3 0 Ubiquitin interaction motif RPM2 PF08579.6 KND99333.1 - 4e-26 91.5 0.7 4e-26 91.5 0.5 3.0 3 0 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) Mannosyl_trans3 PF11051.3 KND99334.1 - 8e-59 199.1 0.0 1.2e-58 198.6 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Adaptin_N PF01602.15 KND99335.1 - 8.9e-91 304.7 22.8 1.4e-90 304.1 15.8 1.3 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KND99335.1 - 5.7e-47 159.3 0.8 5.7e-47 159.3 0.6 2.2 3 0 0 3 3 3 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KND99335.1 - 6.4e-10 39.1 0.7 0.0034 17.6 0.0 5.0 3 2 1 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 KND99335.1 - 9.1e-06 26.0 1.3 0.032 14.7 0.1 4.2 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.17 KND99335.1 - 0.0009 19.1 4.9 3.4 7.9 0.1 6.6 7 0 0 7 7 7 1 HEAT repeat Cnd1 PF12717.2 KND99335.1 - 0.0085 15.9 0.1 0.0085 15.9 0.1 5.0 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 CIMR PF00878.13 KND99336.1 - 9.6e-09 35.1 0.7 5e-05 23.1 0.1 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.10 KND99336.1 - 7.3e-08 31.7 0.0 9.9e-08 31.3 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor PRKCSH_1 PF13015.1 KND99336.1 - 0.0054 16.2 0.0 0.0084 15.5 0.0 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF4131 PF13567.1 KND99336.1 - 0.067 12.5 0.9 4.2 6.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DIL PF01843.14 KND99337.1 - 2.1e-16 59.7 5.1 1.6e-13 50.4 0.1 3.1 3 0 0 3 3 3 2 DIL domain Ank PF00023.25 KND99337.1 - 1.1e-11 43.8 0.1 2.9e-05 23.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KND99337.1 - 1e-09 38.5 0.0 3.1e-09 37.0 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KND99337.1 - 5.1e-09 36.0 0.1 4.1e-05 23.6 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KND99337.1 - 3.5e-06 26.7 0.0 0.0011 18.9 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 KND99337.1 - 4.8e-06 26.9 0.6 0.00052 20.4 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ribosomal_L37 PF08561.5 KND99338.1 - 4e-26 90.4 2.3 4.5e-26 90.2 1.6 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 YchF-GTPase_C PF06071.8 KND99339.1 - 9.6e-36 121.4 0.1 2.3e-35 120.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KND99339.1 - 5.5e-13 48.8 0.0 3.1e-12 46.4 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KND99339.1 - 0.0063 15.7 0.0 0.015 14.5 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 KND99339.1 - 0.0076 16.0 0.0 0.018 14.8 0.0 1.7 1 0 0 1 1 1 1 TGS domain AAA_23 PF13476.1 KND99339.1 - 0.41 10.9 4.3 2.8 8.2 2.8 2.3 1 1 0 1 1 1 0 AAA domain DUF1903 PF08991.5 KND99341.1 - 4.4e-29 100.4 10.0 5e-29 100.2 6.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 KND99341.1 - 0.0036 17.1 5.9 0.0036 17.1 4.1 1.8 2 0 0 2 2 2 1 CHCH domain DUF758 PF05527.6 KND99341.1 - 0.075 12.6 0.0 0.086 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF758) Cmc1 PF08583.5 KND99341.1 - 1 9.1 10.1 0.28 10.9 2.3 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF1640 PF07798.6 KND99342.1 - 8.5e-12 45.4 3.0 1.3e-11 44.9 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) TMEM247 PF15444.1 KND99343.1 - 0.05 13.4 0.2 0.083 12.7 0.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 Thy1 PF02511.10 KND99343.1 - 0.13 11.5 1.8 0.6 9.4 1.1 2.2 1 1 0 1 1 1 0 Thymidylate synthase complementing protein Hs1pro-1_C PF07014.7 KND99344.1 - 0.031 13.6 0.2 0.093 12.0 0.2 1.7 1 1 1 2 2 2 0 Hs1pro-1 protein C-terminus Pkinase PF00069.20 KND99345.1 - 0.0049 16.0 0.0 0.041 13.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 KND99345.1 - 0.01 15.8 0.0 14 6.1 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.1 KND99345.1 - 0.03 14.8 0.0 20 5.8 0.0 3.4 3 1 0 3 3 3 0 HEAT-like repeat Cnd1 PF12717.2 KND99345.1 - 0.86 9.4 6.2 0.15 11.9 0.4 2.3 3 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 OPT PF03169.10 KND99347.1 - 2.2e-179 597.8 43.0 2.6e-179 597.6 29.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein p450 PF00067.17 KND99348.1 - 2.1e-64 217.7 0.0 2.7e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cellulase PF00150.13 KND99350.1 - 2e-08 33.7 3.2 5.8e-08 32.2 0.1 2.7 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Scm3 PF10384.4 KND99350.1 - 0.17 11.4 0.6 0.63 9.5 0.0 2.2 3 0 0 3 3 3 0 Centromere protein Scm3 DUF2076 PF09849.4 KND99351.1 - 0.37 10.7 2.7 0.15 12.1 0.4 1.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) MFS_1 PF07690.11 KND99353.1 - 3.8e-16 58.7 36.8 6.4e-13 48.1 25.3 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Ninjurin PF04923.7 KND99353.1 - 0.0064 16.1 0.0 0.58 9.9 0.0 3.3 3 0 0 3 3 3 1 Ninjurin DUF872 PF05915.7 KND99353.1 - 0.036 13.9 1.3 0.27 11.1 0.0 2.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF624 PF04854.9 KND99353.1 - 0.059 13.2 0.2 0.059 13.2 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function, DUF624 DUF4225 PF13988.1 KND99353.1 - 0.19 11.2 6.1 1.4 8.3 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) MFS_1 PF07690.11 KND99354.1 - 1.7e-12 46.7 36.0 1.1e-10 40.8 24.3 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily MatE PF01554.13 KND99358.1 - 8.8e-41 139.2 28.2 6.3e-28 97.4 7.7 2.6 3 0 0 3 3 3 2 MatE MFS_1 PF07690.11 KND99359.1 - 1.6e-07 30.4 3.7 1.3e-06 27.4 3.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.3 KND99359.1 - 0.0044 15.5 1.4 0.12 10.8 0.6 2.1 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like DUF1275 PF06912.6 KND99359.1 - 0.012 14.7 1.8 0.017 14.3 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) DUF4203 PF13886.1 KND99359.1 - 0.015 14.7 1.4 0.015 14.7 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) EcsB PF05975.7 KND99359.1 - 0.046 12.1 0.0 0.064 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB EphA2_TM PF14575.1 KND99359.1 - 0.097 13.0 0.1 0.61 10.5 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 KND99359.1 - 0.13 11.9 0.1 1.2 8.8 0.0 2.0 1 1 1 2 2 2 0 TMEM154 protein family VIT1 PF01988.14 KND99359.1 - 0.29 10.5 7.7 0.074 12.5 1.2 2.0 1 1 1 2 2 2 0 VIT family COX6C PF02937.10 KND99359.1 - 0.31 10.9 1.3 1.1 9.1 0.0 2.4 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIc MFS_1 PF07690.11 KND99360.1 - 1.3e-23 83.3 8.6 1.7e-23 82.9 6.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily ERGIC_N PF13850.1 KND99360.1 - 0.12 12.3 0.1 0.12 12.3 0.0 2.9 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) AcetylCoA_hydro PF02550.10 KND99362.1 - 6.3e-64 215.3 0.0 1e-63 214.6 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 KND99362.1 - 8.8e-40 135.8 0.0 1.4e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CTDII PF01556.13 KND99363.1 - 1.6e-25 88.7 3.7 6.9e-22 77.1 0.4 3.3 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 KND99363.1 - 1.8e-23 82.0 5.4 3.2e-23 81.2 3.7 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KND99363.1 - 1.2e-11 44.4 17.5 2.2e-11 43.6 12.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Cytochrome_C7 PF14522.1 KND99363.1 - 1.3 8.6 12.9 0.35 10.5 6.3 2.0 1 1 0 1 1 1 0 Cytochrome c7 HypA PF01155.14 KND99363.1 - 9.4 5.9 8.0 4 7.1 0.6 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Ran_BP1 PF00638.13 KND99364.1 - 4.9e-15 55.6 0.0 7.8e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.6 KND99364.1 - 6.6e-09 36.0 0.0 2e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 NUP50 (Nucleoporin 50 kDa) Pox_P4B PF03292.9 KND99364.1 - 0.011 13.6 0.2 0.015 13.2 0.1 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein Ribosomal_S25 PF03297.10 KND99365.1 - 1.8e-45 153.3 3.4 1.9e-45 153.1 2.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Ftsk_gamma PF09397.5 KND99365.1 - 0.0028 17.3 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 Ftsk gamma domain HTH_CodY PF08222.6 KND99365.1 - 0.041 13.2 0.1 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain Polyketide_cyc PF03364.15 KND99366.1 - 9.1e-13 48.3 0.1 1.2e-12 47.9 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 KND99366.1 - 0.0036 17.4 0.0 0.0047 17.0 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport A_amylase_inhib PF01356.14 KND99366.1 - 0.047 13.4 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha amylase inhibitor PH_9 PF15410.1 KND99367.1 - 4.3e-05 23.6 0.2 0.006 16.7 0.0 2.9 3 0 0 3 3 3 1 Pleckstrin homology domain Nucleoplasmin PF03066.10 KND99367.1 - 0.58 9.6 6.7 1.1 8.8 4.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin EBV-NA3 PF05009.7 KND99367.1 - 1.6 7.9 4.4 2.9 7.0 3.0 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Pcc1 PF09341.5 KND99369.1 - 2.7e-20 72.1 0.1 3e-20 72.0 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 LXG PF04740.7 KND99369.1 - 0.024 14.4 0.0 0.043 13.6 0.0 1.3 1 1 0 1 1 1 0 LXG domain of WXG superfamily M157 PF11624.3 KND99369.1 - 0.074 12.1 0.1 0.079 12.0 0.1 1.1 1 0 0 1 1 1 0 MHC class I-like protein M157 DNA_pol_A PF00476.15 KND99370.1 - 7e-89 298.1 0.0 9.7e-89 297.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 KND99370.1 - 0.02 14.3 0.1 0.35 10.3 0.0 2.3 2 0 0 2 2 2 0 3'-5' exonuclease CENP-B_dimeris PF09026.5 KND99372.1 - 0.46 10.7 7.1 5.9 7.1 3.6 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sds3 PF08598.6 KND99373.1 - 0.22 10.9 11.9 0.11 11.9 5.5 2.3 2 0 0 2 2 2 0 Sds3-like tRNA_NucTransf2 PF09249.6 KND99374.1 - 0.067 13.0 0.0 0.068 13.0 0.0 1.1 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain PWWP PF00855.12 KND99375.1 - 8.9e-15 54.6 1.8 1.1e-14 54.4 0.1 2.0 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.6 KND99375.1 - 4.6e-05 22.8 1.1 6.6e-05 22.3 0.1 1.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain DUF1015 PF06245.6 KND99377.1 - 0.043 12.3 0.0 0.043 12.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1015) eIF-5a PF01287.15 KND99378.1 - 1.7e-28 98.3 0.8 2.4e-28 97.8 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 KND99378.1 - 2e-05 24.1 0.8 4.5e-05 23.0 0.6 1.6 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 KND99378.1 - 0.014 15.2 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain TcdB_toxin_midN PF12256.3 KND99378.1 - 0.041 13.3 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region DUF3893 PF13032.1 KND99379.1 - 0.099 12.7 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3893) zf-RING_2 PF13639.1 KND99381.1 - 3e-14 52.5 6.8 5.5e-14 51.7 4.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KND99381.1 - 2.1e-08 34.1 1.7 4.5e-08 33.0 1.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KND99381.1 - 6.8e-07 28.9 5.0 1.3e-06 28.0 3.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KND99381.1 - 2.1e-06 27.6 7.6 3.8e-06 26.8 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KND99381.1 - 2.3e-06 27.1 5.2 4.4e-06 26.2 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KND99381.1 - 3.9e-05 23.4 1.8 7.2e-05 22.5 1.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 KND99381.1 - 4.4e-05 23.0 3.8 7.1e-05 22.3 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KND99381.1 - 0.013 15.2 1.1 0.057 13.1 0.2 2.3 1 1 1 2 2 2 0 RING-type zinc-finger PHD PF00628.24 KND99381.1 - 0.022 14.4 5.5 0.041 13.5 3.8 1.5 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.2 KND99381.1 - 0.062 13.3 6.7 0.12 12.4 4.7 1.5 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 KND99381.1 - 0.14 11.9 5.8 0.39 10.4 4.0 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 KND99381.1 - 2.7 7.6 7.3 5.4 6.6 5.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 KND99383.1 - 1.5e-11 43.7 0.0 2.9e-11 42.8 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND99383.1 - 2.8e-11 43.2 0.0 4.3e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND99383.1 - 0.00024 20.8 0.0 0.00041 20.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rox3 PF08633.5 KND99384.1 - 0.0012 19.1 0.1 0.0013 19.0 0.1 1.0 1 0 0 1 1 1 1 Rox3 mediator complex subunit Apt1 PF10351.4 KND99385.1 - 6e-98 328.6 22.2 6e-98 328.6 15.4 1.9 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27 PF10344.4 KND99385.1 - 1.3e-93 314.3 13.9 1.3e-93 314.3 9.7 2.3 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Fmp27_WPPW PF10359.4 KND99385.1 - 1.5e-79 267.6 22.4 1.6e-46 158.7 0.2 3.5 2 1 0 3 3 3 2 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 KND99385.1 - 1.2e-50 171.4 0.0 8.4e-50 168.7 0.0 2.5 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 KND99385.1 - 4.2e-44 150.0 0.7 2e-43 147.8 0.5 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 KND99385.1 - 1.6e-25 89.5 0.0 1.1e-24 86.8 0.0 2.7 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Ribosomal_L32e PF01655.13 KND99389.1 - 7.5e-11 42.0 0.6 8.2e-11 41.9 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Pkinase PF00069.20 KND99390.1 - 4.1e-41 140.8 0.0 5.7e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND99390.1 - 8.4e-23 80.7 0.0 1.4e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND99390.1 - 5.3e-08 32.1 0.0 8.7e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KND99390.1 - 0.034 13.4 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.9 KND99390.1 - 0.086 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KND99390.1 - 0.089 11.6 0.1 0.18 10.6 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 SUR7 PF06687.7 KND99393.1 - 2e-31 109.2 13.0 2.4e-31 108.9 9.0 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 KND99393.1 - 0.24 11.2 12.7 0.03 14.1 5.8 1.6 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF4271 PF14093.1 KND99393.1 - 0.74 9.4 16.9 0.053 13.1 7.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) PRA1 PF03208.14 KND99393.1 - 4 6.7 14.7 0.36 10.1 5.2 2.3 2 1 0 2 2 2 0 PRA1 family protein Claudin_3 PF06653.6 KND99393.1 - 4.1 7.1 12.2 0.15 11.7 4.4 1.6 2 0 0 2 2 2 0 Tight junction protein, Claudin-like Lipase_3 PF01764.20 KND99394.1 - 2.3e-07 30.5 0.0 5.8e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KND99394.1 - 0.02 14.6 0.0 0.063 13.0 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.7 KND99394.1 - 0.053 13.2 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.8 KND99394.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein HMG_box PF00505.14 KND99395.1 - 1.7e-06 28.2 3.1 4.3e-06 26.8 2.2 1.7 1 1 0 1 1 1 1 HMG (high mobility group) box Phos_pyr_kin PF08543.7 KND99395.1 - 1.6e-05 24.2 0.0 3.2e-05 23.2 0.0 1.4 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 KND99395.1 - 0.00031 19.9 0.0 0.0023 17.1 0.0 2.1 2 0 0 2 2 2 1 pfkB family carbohydrate kinase WD40 PF00400.27 KND99396.1 - 4.8e-06 26.2 0.0 9.4e-05 22.1 0.0 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat SAP PF02037.22 KND99398.1 - 6.2e-06 25.5 0.0 1.4e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 SAP domain zf-Di19 PF05605.7 KND99398.1 - 0.0077 16.3 0.1 0.45 10.6 0.0 2.6 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 KND99398.1 - 0.017 14.8 0.0 0.017 14.8 0.0 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Sgf11 PF08209.6 KND99398.1 - 0.22 10.8 0.1 0.22 10.8 0.1 2.4 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zf-TFIIB PF13453.1 KND99398.1 - 0.58 9.3 2.2 3.4 6.9 0.2 2.9 3 0 0 3 3 3 0 Transcription factor zinc-finger Rad50_zn_hook PF04423.9 KND99398.1 - 5 6.6 9.6 1.4 8.4 0.1 3.8 4 0 0 4 4 4 0 Rad50 zinc hook motif Form_Nir_trans PF01226.12 KND99400.1 - 2.4e-63 213.3 23.7 2.9e-63 213.0 16.4 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter DEAD PF00270.24 KND99401.1 - 1.6e-39 135.1 1.4 3.8e-39 133.8 1.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KND99401.1 - 5.5e-23 80.6 0.1 1.5e-10 40.7 0.0 3.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 KND99401.1 - 7.1e-06 25.9 1.3 1.8e-05 24.6 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KND99401.1 - 0.0026 17.8 0.1 0.0066 16.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 KND99401.1 - 0.019 14.7 1.0 0.048 13.4 0.1 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain DUF3135 PF11333.3 KND99401.1 - 0.084 13.0 0.3 7.4 6.8 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) Mpv17_PMP22 PF04117.7 KND99402.1 - 7.1e-07 28.7 9.0 1.3e-06 27.9 5.7 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family YL1 PF05764.8 KND99406.1 - 8.1e-44 150.0 52.9 8.1e-44 150.0 36.7 5.2 4 2 0 4 4 4 1 YL1 nuclear protein YL1_C PF08265.6 KND99406.1 - 7.7e-10 38.1 0.1 1.7e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Methyltransf_23 PF13489.1 KND99407.1 - 5.1e-24 84.8 0.0 7.7e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND99407.1 - 7.4e-16 58.4 0.0 5.3e-15 55.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND99407.1 - 8e-14 51.9 0.0 1.8e-13 50.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND99407.1 - 2.1e-12 46.9 0.0 3.2e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND99407.1 - 1.3e-10 41.8 0.0 2.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KND99407.1 - 4e-06 26.1 0.0 5.4e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 KND99407.1 - 5.1e-06 26.7 0.0 9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND99407.1 - 2.7e-05 24.1 0.0 4.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KND99407.1 - 0.00016 20.9 0.0 0.00025 20.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 KND99407.1 - 0.00024 20.5 0.0 0.00036 19.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.6 KND99407.1 - 0.0034 16.1 0.0 0.0058 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.7 KND99407.1 - 0.012 14.9 0.0 0.033 13.5 0.0 1.6 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW DREV PF05219.7 KND99407.1 - 0.013 14.4 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.9 KND99407.1 - 0.07 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain FliG_N PF14842.1 KND99407.1 - 0.095 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 FliG N-terminal domain CAP_N PF01213.14 KND99408.1 - 1.4e-97 326.7 1.2 2e-97 326.2 0.8 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 KND99408.1 - 4e-51 172.5 3.3 5.9e-51 171.9 2.3 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Methyltransf_6 PF03737.10 KND99408.1 - 0.025 14.4 0.2 0.065 13.1 0.1 1.7 2 0 0 2 2 2 0 Demethylmenaquinone methyltransferase Actin PF00022.14 KND99409.1 - 6.4e-48 163.1 0.0 1.6e-25 89.3 0.0 2.3 2 0 0 2 2 2 2 Actin PIN_4 PF13638.1 KND99409.1 - 0.038 14.1 0.6 0.038 14.1 0.4 2.3 3 0 0 3 3 3 0 PIN domain Nol1_Nop2_Fmu PF01189.12 KND99410.1 - 6.6e-108 360.3 0.0 1e-107 359.7 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family Met_10 PF02475.11 KND99410.1 - 0.001 18.6 0.0 0.0022 17.5 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein FtsJ PF01728.14 KND99410.1 - 0.0016 18.4 0.0 0.0038 17.2 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 KND99410.1 - 0.004 16.7 0.1 0.0095 15.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Bradykinin PF06753.7 KND99410.1 - 1.6 8.2 4.3 3.2 7.3 3.0 1.5 1 0 0 1 1 1 0 Bradykinin Gcd10p PF04189.8 KND99411.1 - 1.9e-97 325.9 2.4 3.2e-97 325.2 1.7 1.3 1 0 0 1 1 1 1 Gcd10p family PsbP PF01789.11 KND99411.1 - 0.053 12.9 0.1 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 PsbP Methyltransf_26 PF13659.1 KND99412.1 - 8.4e-14 51.6 0.0 2.6e-13 50.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KND99412.1 - 2.4e-13 49.8 0.0 3.5e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 KND99412.1 - 3.4e-12 46.2 0.0 5e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND99412.1 - 2e-10 41.2 0.0 3.9e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND99412.1 - 5.1e-10 39.6 0.0 8.7e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND99412.1 - 3.7e-07 30.5 0.1 8.3e-07 29.4 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.8 KND99412.1 - 6.4e-07 28.7 0.0 9.4e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 KND99412.1 - 0.00018 21.1 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.11 KND99412.1 - 0.00097 18.3 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Ubie_methyltran PF01209.13 KND99412.1 - 0.0011 18.1 0.1 0.0016 17.5 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.5 KND99412.1 - 0.0031 17.0 0.0 0.0049 16.4 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_23 PF13489.1 KND99412.1 - 0.0039 16.9 0.0 0.0066 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KND99412.1 - 0.0062 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.7 KND99412.1 - 0.011 16.1 0.1 0.024 15.0 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Eco57I PF07669.6 KND99412.1 - 0.035 14.4 0.0 0.24 11.7 0.0 2.2 2 0 0 2 2 2 0 Eco57I restriction-modification methylase Methyltransf_10 PF05971.7 KND99412.1 - 0.11 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF890) Methyltransf_32 PF13679.1 KND99412.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TRM PF02005.11 KND99412.1 - 0.14 11.0 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase AviRa PF11599.3 KND99412.1 - 0.14 11.1 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa S4 PF01479.20 KND99413.1 - 1.8e-16 59.2 0.1 3.6e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 KND99413.1 - 0.0036 16.8 0.0 0.0078 15.7 0.0 1.5 1 0 0 1 1 1 1 S4 domain DLD PF14878.1 KND99413.1 - 0.099 12.7 0.9 0.29 11.2 0.2 2.1 2 0 0 2 2 2 0 Death-like domain of SPT6 LTXXQ PF07813.7 KND99413.1 - 0.11 12.9 3.1 0.24 11.8 2.2 1.6 1 0 0 1 1 1 0 LTXXQ motif family protein Eaf7 PF07904.8 KND99414.1 - 9.3e-18 63.9 0.2 9.3e-18 63.9 0.2 2.3 2 1 0 2 2 2 1 Chromatin modification-related protein EAF7 AA_permease PF00324.16 KND99416.1 - 2.8e-121 405.1 49.9 3.5e-121 404.8 34.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND99416.1 - 1.6e-34 119.1 55.6 2.1e-34 118.8 38.6 1.2 1 0 0 1 1 1 1 Amino acid permease SUN PF03856.8 KND99421.1 - 1.1e-104 349.1 17.4 1.6e-104 348.5 12.1 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Gar1 PF04410.9 KND99423.1 - 3.7e-46 156.3 2.4 3.7e-46 156.3 1.7 2.4 2 1 1 3 3 3 1 Gar1/Naf1 RNA binding region MutS_V PF00488.16 KND99424.1 - 3.9e-80 268.6 0.0 6.2e-80 267.9 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KND99424.1 - 2.4e-26 92.7 5.5 4.3e-25 88.6 3.8 2.4 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KND99424.1 - 4.1e-24 84.7 0.0 2e-23 82.5 0.0 2.2 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 KND99424.1 - 3.3e-11 43.4 0.0 8.7e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain II Viral_P18 PF04521.8 KND99424.1 - 0.044 13.2 0.2 0.14 11.6 0.1 1.8 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein N-SET PF11764.3 KND99425.1 - 1.4e-45 155.1 2.8 1.4e-45 155.1 1.9 3.4 4 0 0 4 4 4 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 KND99425.1 - 1.3e-25 88.4 1.7 2.6e-25 87.5 1.1 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 KND99425.1 - 5.1e-24 85.4 0.2 5.1e-24 85.4 0.1 3.9 4 2 0 4 4 4 1 SET domain RRM_6 PF14259.1 KND99425.1 - 0.037 14.0 0.0 0.089 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ETC_C1_NDUFA4 PF04800.7 KND99426.1 - 4.1e-29 100.4 0.5 4.9e-29 100.1 0.3 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region ORC6 PF05460.8 KND99427.1 - 7.5e-70 235.7 0.0 9.7e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) PDZ_1 PF12812.2 KND99428.1 - 6.5e-51 170.1 0.0 1.4e-34 117.7 0.0 3.0 3 0 0 3 3 3 2 PDZ-like domain Trypsin_2 PF13365.1 KND99428.1 - 1e-17 64.2 0.2 1.5e-12 47.5 0.0 3.3 3 0 0 3 3 3 2 Trypsin-like peptidase domain PDZ_2 PF13180.1 KND99428.1 - 1.4e-12 47.3 0.9 0.0065 16.3 0.0 4.4 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.19 KND99428.1 - 4.9e-07 29.8 0.0 1.5e-05 25.0 0.0 3.0 3 0 0 3 3 3 1 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 KND99428.1 - 5.1e-06 26.2 0.0 1.6e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Trypsin Peptidase_S7 PF00949.16 KND99428.1 - 0.00091 18.6 0.1 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.11 KND99428.1 - 0.0029 17.0 0.4 0.0046 16.3 0.3 1.3 1 0 0 1 1 1 1 Putative peptidase (DUF31) Tricorn_PDZ PF14685.1 KND99428.1 - 0.0035 17.1 0.0 0.4 10.5 0.0 3.3 4 0 0 4 4 4 1 Tricorn protease PDZ domain Peptidase_S46 PF10459.4 KND99428.1 - 0.023 13.1 1.4 0.08 11.3 0.1 2.0 2 0 0 2 2 2 0 Peptidase S46 Peptidase_S3 PF00944.14 KND99428.1 - 0.096 12.0 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Alphavirus core protein LysM PF01476.15 KND99428.1 - 0.099 12.5 0.0 0.43 10.5 0.0 2.1 2 0 0 2 2 2 0 LysM domain Ribosomal_L35p PF01632.14 KND99429.1 - 9.4e-06 25.4 6.9 1.4e-05 24.9 4.8 1.5 1 1 0 1 1 1 1 Ribosomal protein L35 Lant_dehyd_N PF04737.8 KND99429.1 - 0.0079 16.1 0.0 0.0085 16.0 0.0 1.0 1 0 0 1 1 1 1 Lantibiotic dehydratase, N terminus Frag1 PF10277.4 KND99430.1 - 1.1e-40 139.4 13.1 1.1e-40 139.4 9.1 3.2 3 1 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 KND99430.1 - 2.8e-05 24.2 0.0 4.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NDUFB10 PF10249.4 KND99431.1 - 0.00063 19.9 0.1 0.00064 19.8 0.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Homeobox PF00046.24 KND99432.1 - 0.1 12.2 0.1 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Homeobox domain DUF3530 PF12048.3 KND99432.1 - 0.12 11.3 0.0 0.12 11.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) ATP-synt PF00231.14 KND99433.1 - 2.9e-70 236.8 10.2 3.4e-70 236.6 7.1 1.0 1 0 0 1 1 1 1 ATP synthase NTS PF15447.1 KND99433.1 - 0.01 16.1 0.2 0.04 14.3 0.0 2.0 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 ChlamPMP_M PF07548.6 KND99433.1 - 0.082 12.6 0.2 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain EMP70 PF02990.11 KND99434.1 - 1.8e-114 383.0 12.8 2.3e-114 382.7 8.9 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF962 PF06127.6 KND99434.1 - 0.014 15.2 1.4 0.1 12.4 0.0 3.1 2 2 0 2 2 2 0 Protein of unknown function (DUF962) TPR_11 PF13414.1 KND99435.1 - 1.1e-37 127.5 6.4 1.5e-12 46.9 0.1 7.6 5 3 2 7 7 7 6 TPR repeat TPR_1 PF00515.23 KND99435.1 - 1.3e-36 122.7 12.2 6.9e-08 31.7 0.0 9.3 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 KND99435.1 - 9.7e-35 115.6 11.6 3.1e-05 23.5 0.0 9.9 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_8 PF13181.1 KND99435.1 - 5.3e-30 100.9 7.0 1.5e-06 27.5 0.0 8.0 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 KND99435.1 - 1.1e-25 89.6 11.1 3e-06 27.7 0.1 8.5 7 2 2 9 9 9 6 Tetratricopeptide repeat Apc3 PF12895.2 KND99435.1 - 2.2e-22 78.9 19.0 4.9e-15 55.4 1.0 4.2 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KND99435.1 - 1.1e-19 70.1 12.0 1.4e-05 24.9 0.1 7.3 5 3 2 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 KND99435.1 - 2.2e-19 67.9 13.6 0.051 13.7 0.0 9.8 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 KND99435.1 - 1.8e-15 56.9 8.6 0.044 14.1 0.0 7.3 6 1 2 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 KND99435.1 - 2.3e-15 55.6 2.5 0.024 15.2 0.1 8.3 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 KND99435.1 - 3e-12 45.3 4.4 0.13 12.1 0.0 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 KND99435.1 - 3e-10 39.8 6.1 1.3 9.6 0.0 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 KND99435.1 - 1.3e-09 37.7 1.6 0.0039 16.9 0.0 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_3 PF07720.7 KND99435.1 - 0.00029 20.5 2.5 0.0097 15.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.4 KND99435.1 - 0.021 14.7 1.0 1.6 8.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.15 KND99435.1 - 0.56 10.2 5.6 3.4 7.8 0.0 4.6 6 0 0 6 6 5 0 PPR repeat PH PF00169.24 KND99437.1 - 5.6e-13 49.0 0.0 1.6e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.1 KND99437.1 - 1.1e-09 37.7 0.0 2.3e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KND99437.1 - 7.8e-09 34.7 0.1 1.9e-08 33.5 0.0 1.7 2 0 0 2 2 2 1 SH3 domain PH_11 PF15413.1 KND99437.1 - 4.5e-07 30.1 1.0 3.4e-06 27.2 0.1 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain SAM_2 PF07647.12 KND99437.1 - 9.8e-07 28.5 0.0 2.6e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 KND99437.1 - 3.3e-05 23.2 0.0 8.3e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 KND99437.1 - 0.0066 16.5 0.1 0.013 15.6 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pex14_N PF04695.8 KND99437.1 - 0.018 15.0 0.4 0.018 15.0 0.3 3.9 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MFS_1 PF07690.11 KND99441.1 - 7e-37 126.9 24.6 7e-37 126.9 17.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily SpoVAB PF13782.1 KND99441.1 - 0.052 13.5 0.7 0.052 13.5 0.5 2.1 2 1 1 3 3 3 0 Stage V sporulation protein AB DUF4064 PF13273.1 KND99441.1 - 0.11 12.6 0.0 0.11 12.6 0.0 3.6 4 1 0 4 4 4 0 Protein of unknown function (DUF4064) DUF3611 PF12263.3 KND99441.1 - 0.54 9.6 5.7 0.44 9.9 0.6 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3611) PAP1 PF08601.5 KND99443.1 - 7.5e-40 137.6 9.1 4.2e-36 125.3 4.9 3.3 2 1 2 4 4 4 2 Transcription factor PAP1 bZIP_1 PF00170.16 KND99443.1 - 3.3e-08 33.3 10.6 6.8e-08 32.3 7.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KND99443.1 - 2.6e-05 23.9 12.3 5.4e-05 22.9 8.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KND99443.1 - 0.0042 17.3 10.4 0.0079 16.4 7.2 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Herpes_IE2_3 PF03361.9 KND99443.1 - 0.048 12.9 0.1 0.09 12.1 0.1 1.4 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 Glutaredoxin2_C PF04399.8 KND99443.1 - 0.071 12.6 0.5 0.13 11.8 0.3 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF444 PF04285.7 KND99443.1 - 0.1 11.2 2.4 0.16 10.5 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF444) DivIC PF04977.10 KND99443.1 - 0.21 11.1 3.1 0.39 10.2 2.2 1.4 1 0 0 1 1 1 0 Septum formation initiator Med21 PF11221.3 KND99443.1 - 1.1 9.2 5.2 2.8 7.9 3.0 2.3 1 1 0 1 1 1 0 Subunit 21 of Mediator complex DUF2616 PF11077.3 KND99444.1 - 0.12 11.8 0.2 0.13 11.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) Mak10 PF04112.8 KND99445.1 - 3.7e-30 104.3 0.1 2.3e-29 101.7 0.0 2.3 2 1 0 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Cnd3 PF12719.2 KND99446.1 - 8.9e-86 287.5 0.9 8.8e-85 284.2 0.6 2.3 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 KND99446.1 - 3.6e-07 30.3 2.7 0.0017 18.5 0.0 5.3 3 2 3 6 6 6 2 HEAT repeats HEAT PF02985.17 KND99446.1 - 2e-06 27.3 2.0 1.4 9.1 0.0 6.3 7 0 0 7 7 7 2 HEAT repeat Sterol_MT_C PF08498.5 KND99447.1 - 8.5e-31 105.7 0.6 1.2e-30 105.1 0.4 1.2 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 KND99447.1 - 5.2e-18 65.3 0.0 9.2e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND99447.1 - 1.2e-16 60.7 0.0 1.7e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KND99447.1 - 2e-12 47.1 0.0 3.2e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND99447.1 - 4.3e-11 43.1 0.0 8.2e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND99447.1 - 4.3e-11 43.0 0.0 9.6e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KND99447.1 - 4.6e-11 42.3 0.6 6.4e-11 41.8 0.4 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 KND99447.1 - 1.1e-10 42.0 0.0 2.5e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND99447.1 - 1.4e-08 34.7 0.0 3.5e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND99447.1 - 3.4e-07 29.6 0.0 5.6e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.5 KND99447.1 - 1.9e-05 24.2 0.1 3.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 KND99447.1 - 0.0013 17.8 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KND99447.1 - 0.0016 17.8 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KND99447.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 KND99447.1 - 0.049 13.2 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 KND99447.1 - 0.094 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 KND99447.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Lactococcin_972 PF09683.5 KND99447.1 - 0.13 12.6 3.3 0.41 11.0 2.3 1.8 1 0 0 1 1 1 0 Bacteriocin (Lactococcin_972) Glyco_hydro_76 PF03663.9 KND99449.1 - 1.7e-41 142.8 1.0 2.2e-41 142.4 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KND99449.1 - 7.1e-05 22.0 2.5 0.19 10.7 0.1 2.9 1 1 2 3 3 3 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.8 KND99449.1 - 0.0004 19.7 0.0 0.0012 18.1 0.0 1.7 2 0 0 2 2 2 1 D-glucuronyl C5-epimerase C-terminus GlcNAc_2-epim PF07221.6 KND99449.1 - 0.00054 19.0 0.1 0.0086 15.1 0.0 2.5 2 1 1 3 3 3 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) DUF1680 PF07944.7 KND99449.1 - 0.0033 15.7 0.1 0.2 9.8 0.0 2.2 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) WD40 PF00400.27 KND99450.1 - 6.1e-17 60.7 7.9 0.00054 19.7 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ACBP PF00887.14 KND99451.1 - 7.2e-10 38.4 0.3 1.4e-09 37.5 0.2 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Herpes_IE2_3 PF03361.9 KND99453.1 - 0.043 13.1 0.0 0.047 13.0 0.0 1.0 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 Ribosomal_L11_N PF03946.9 KND99454.1 - 1e-17 63.3 0.2 3.1e-17 61.7 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KND99454.1 - 1.1e-11 44.6 0.3 2.8e-11 43.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Asp PF00026.18 KND99455.1 - 1.9e-61 208.0 0.5 6.3e-50 170.2 0.2 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KND99455.1 - 7.1e-06 26.4 0.1 2.9 8.4 0.0 3.5 3 0 0 3 3 3 3 Aspartyl protease TAXi_N PF14543.1 KND99455.1 - 9.5e-05 22.3 0.1 0.23 11.4 0.0 2.4 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal RVP PF00077.15 KND99455.1 - 0.00041 20.2 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 2 Retroviral aspartyl protease RA PF00788.18 KND99456.1 - 2.2e-14 53.7 0.1 4.4e-14 52.7 0.1 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.12 KND99456.1 - 6.8e-08 32.2 0.6 2.4e-07 30.5 0.0 2.2 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KND99456.1 - 7.1e-05 22.9 0.0 0.00017 21.6 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4335 PF14233.1 KND99456.1 - 0.005 16.3 0.4 0.011 15.2 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4335) Ste50p-SAM PF09235.5 KND99456.1 - 0.069 13.1 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Ste50p, sterile alpha motif FYDLN_acid PF09538.5 KND99457.1 - 0.043 14.3 1.3 0.05 14.1 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF2633 PF11119.3 KND99457.1 - 7.5 6.3 7.0 0.54 10.0 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) Metallophos PF00149.23 KND99460.1 - 8.7e-11 41.5 0.0 2.4e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KND99460.1 - 5.7e-07 29.5 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ycf1 PF05758.7 KND99460.1 - 0.19 9.3 5.7 0.25 9.0 4.0 1.1 1 0 0 1 1 1 0 Ycf1 Pkinase PF00069.20 KND99462.1 - 5.2e-65 219.1 0.0 7.4e-65 218.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND99462.1 - 7.5e-49 166.1 0.0 1.2e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 KND99462.1 - 2.1e-27 95.0 0.0 5.2e-27 93.8 0.0 1.7 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 KND99462.1 - 2.2e-09 37.3 0.1 5.9e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KND99462.1 - 3.1e-09 36.5 0.1 1.1e-08 34.8 0.0 2.0 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 KND99462.1 - 5.4e-06 25.5 0.0 0.006 15.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase PF00069.20 KND99464.1 - 8.2e-36 123.4 0.0 7.1e-22 77.7 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KND99464.1 - 1.2e-15 57.2 0.0 3.8e-12 45.8 0.0 3.0 2 2 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KND99464.1 - 0.00035 20.3 0.0 0.0009 19.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KND99464.1 - 0.00089 18.6 0.1 0.0021 17.4 0.0 1.6 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 KND99464.1 - 0.0014 18.0 0.1 0.013 14.8 0.0 2.2 2 0 0 2 2 2 1 RIO1 family ADH_zinc_N PF00107.21 KND99466.1 - 4.2e-11 42.4 0.0 6.9e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KND99466.1 - 1.3e-08 35.7 0.0 4e-08 34.2 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KND99466.1 - 0.0032 17.2 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DFP PF04127.10 KND99466.1 - 0.022 14.3 0.0 0.076 12.6 0.0 1.9 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein CSD PF00313.17 KND99467.1 - 0.066 12.9 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain Acetyltransf_1 PF00583.19 KND99469.1 - 6.7e-14 51.6 0.0 9.2e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KND99469.1 - 9.5e-10 38.5 0.0 1.3e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KND99469.1 - 6.3e-05 22.8 0.0 7.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KND99469.1 - 0.048 13.7 0.0 0.061 13.4 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KND99469.1 - 0.06 13.2 0.0 0.064 13.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LSM PF01423.17 KND99470.1 - 0.00032 20.1 0.0 0.00034 20.1 0.0 1.0 1 0 0 1 1 1 1 LSM domain IncA PF04156.9 KND99471.1 - 0.5 9.9 7.2 0.82 9.2 5.0 1.2 1 0 0 1 1 1 0 IncA protein Ribosomal_S2 PF00318.15 KND99474.1 - 1.4e-37 129.0 0.0 9.8e-21 73.9 0.0 2.3 2 1 1 3 3 3 2 Ribosomal protein S2 MFS_1 PF07690.11 KND99477.1 - 1.1e-09 37.4 35.7 3.5e-09 35.8 6.7 2.5 3 0 0 3 3 3 2 Major Facilitator Superfamily MFS_1 PF07690.11 KND99480.1 - 1.8e-10 40.1 33.7 2.5e-09 36.2 8.8 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Gpi1 PF05024.10 KND99481.1 - 1.8e-45 154.9 14.2 1.8e-45 154.9 9.9 1.8 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Zn_clus PF00172.13 KND99482.1 - 4.2e-11 42.5 29.2 7.4e-06 25.7 6.2 3.4 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4546 PF15079.1 KND99484.1 - 0.1 11.7 1.1 0.13 11.4 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4546) Aldose_epim PF01263.15 KND99487.1 - 3e-37 128.3 0.2 3.8e-37 128.0 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase PAP2 PF01569.16 KND99489.1 - 7.7e-11 41.7 9.2 7.7e-11 41.7 6.4 2.6 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 KND99489.1 - 2.7e-08 33.5 5.4 2.7e-08 33.5 3.7 1.9 2 0 0 2 2 2 1 PAP2 superfamily Ribosomal_S6 PF01250.12 KND99490.1 - 3.5e-08 33.1 0.0 4.3e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 PNGaseA PF12222.3 KND99493.1 - 0.082 11.7 0.2 0.16 10.8 0.1 1.4 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A MutS_V PF00488.16 KND99494.1 - 3.8e-87 291.5 0.0 6.8e-87 290.7 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KND99494.1 - 5.4e-32 111.2 1.9 1.1e-31 110.1 1.3 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 KND99494.1 - 2.4e-16 59.6 1.0 7.2e-16 58.1 0.7 1.9 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.15 KND99494.1 - 2.1e-09 37.3 0.2 1.3e-08 34.8 0.1 2.2 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 KND99494.1 - 3.4e-07 30.4 2.7 1.1e-06 28.7 0.6 2.8 2 1 0 2 2 2 1 MutS domain II S1_2 PF13509.1 KND99494.1 - 0.026 14.4 0.1 0.095 12.6 0.1 1.9 1 0 0 1 1 1 0 S1 domain CIDE-N PF02017.10 KND99494.1 - 0.037 13.7 0.3 1 9.1 0.0 2.8 2 0 0 2 2 2 0 CIDE-N domain Ceramidase PF05875.7 KND99495.1 - 3.3e-98 328.0 10.8 3.9e-98 327.7 7.5 1.0 1 0 0 1 1 1 1 Ceramidase 7TMR-DISM_7TM PF07695.6 KND99495.1 - 0.022 14.4 13.7 0.21 11.2 2.4 2.3 1 1 1 2 2 2 0 7TM diverse intracellular signalling COX5B PF01215.14 KND99497.1 - 0.012 15.2 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb p450 PF00067.17 KND99498.1 - 1.2e-48 165.8 0.0 1.5e-48 165.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PAPS_reduct PF01507.14 KND99499.1 - 1.9e-43 148.2 0.0 2.5e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Methyltransf_24 PF13578.1 KND99499.1 - 0.083 13.7 0.0 0.15 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DegQ PF08181.6 KND99500.1 - 0.14 11.9 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 DegQ (SacQ) family PDZ_2 PF13180.1 KND99501.1 - 4.6e-07 29.6 0.1 1.1e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 KND99501.1 - 0.00014 21.8 0.0 0.00025 21.0 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.19 KND99501.1 - 0.00017 21.6 0.0 0.0003 20.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Urm1 PF09138.6 KND99502.1 - 1.6e-33 114.6 0.2 1.8e-33 114.5 0.1 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 KND99502.1 - 0.0011 19.4 0.1 0.0013 19.1 0.1 1.2 1 0 0 1 1 1 1 ThiS family DDOST_48kD PF03345.9 KND99504.1 - 4.3e-109 364.8 0.2 4e-107 358.3 0.1 2.0 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF1254 PF06863.7 KND99504.1 - 0.0031 17.3 0.1 0.0061 16.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1254) Prefoldin_2 PF01920.15 KND99505.1 - 8.8e-19 67.2 11.6 1.1e-18 66.8 8.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 KND99505.1 - 2.8e-05 23.7 14.3 0.00015 21.3 3.1 2.1 1 1 0 2 2 2 2 Prefoldin subunit TPR_MLP1_2 PF07926.7 KND99505.1 - 0.0093 15.7 15.6 0.037 13.7 10.8 1.8 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein SAP18 PF06487.7 KND99505.1 - 0.018 14.8 0.9 0.021 14.6 0.6 1.3 1 0 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) Sipho_Gp157 PF05565.6 KND99505.1 - 0.042 13.4 9.4 0.023 14.2 5.2 1.5 1 1 1 2 2 2 0 Siphovirus Gp157 CDC37_N PF03234.9 KND99505.1 - 0.049 13.9 13.0 0.063 13.6 9.0 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding ERK-JNK_inhib PF15002.1 KND99505.1 - 0.077 12.3 5.4 0.43 9.9 0.6 2.2 1 1 0 2 2 2 0 ERK and JNK pathways, inhibitor CK2S PF15011.1 KND99505.1 - 0.19 11.4 3.8 0.33 10.7 2.6 1.4 1 1 0 1 1 1 0 Casein Kinase 2 substrate Tho2 PF11262.3 KND99505.1 - 0.21 10.5 6.7 0.28 10.1 0.0 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Tropomyosin_1 PF12718.2 KND99505.1 - 0.29 10.9 15.7 0.57 10.0 2.8 2.0 2 0 0 2 2 2 0 Tropomyosin like DUF3138 PF11336.3 KND99505.1 - 0.53 8.4 2.2 0.63 8.1 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Rootletin PF15035.1 KND99505.1 - 0.58 10.1 12.5 1.4 8.9 8.7 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion PEP-utilisers_N PF05524.8 KND99505.1 - 0.59 9.9 4.8 1.4 8.7 1.6 2.0 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Sas10_Utp3 PF04000.10 KND99505.1 - 0.62 10.2 3.9 1.6 8.9 0.1 2.3 2 0 0 2 2 2 0 Sas10/Utp3/C1D family PRP1_N PF06424.7 KND99505.1 - 1.4 9.2 8.1 1.9 8.7 0.9 2.0 1 1 1 2 2 2 0 PRP1 splicing factor, N-terminal MRP-S26 PF14943.1 KND99505.1 - 2 7.9 14.3 15 5.1 9.9 1.9 1 1 0 1 1 1 0 Mitochondrial ribosome subunit S26 Peptidase_S46 PF10459.4 KND99505.1 - 2.7 6.3 8.1 2.9 6.2 5.6 1.0 1 0 0 1 1 1 0 Peptidase S46 Occludin_ELL PF07303.8 KND99505.1 - 3.4 8.4 9.7 1.3 9.8 0.8 2.1 2 0 0 2 2 2 0 Occludin homology domain DUF4140 PF13600.1 KND99505.1 - 4.1 7.9 6.3 17 5.8 1.8 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF948 PF06103.6 KND99505.1 - 5.1 7.0 7.2 15 5.5 0.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Spc24 PF08286.6 KND99505.1 - 5.2 6.7 15.6 1.8 8.3 2.9 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ATP-synt_B PF00430.13 KND99505.1 - 5.4 6.8 11.9 2.8 7.7 0.3 2.1 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Seryl_tRNA_N PF02403.17 KND99505.1 - 5.7 7.0 13.0 8 6.5 2.9 2.1 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Syntaxin-6_N PF09177.6 KND99505.1 - 5.7 7.4 9.0 13 6.2 1.5 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal L31 PF09784.4 KND99505.1 - 6.7 6.8 9.1 3.9 7.5 2.4 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 Phage_GPO PF05929.6 KND99505.1 - 8.9 5.4 8.7 2.5 7.2 2.4 1.9 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase ARD PF03079.9 KND99506.1 - 2.5e-41 141.2 1.0 3.1e-41 140.9 0.7 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 KND99506.1 - 1e-09 37.7 0.0 1.7e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KND99506.1 - 4.6e-06 26.3 0.0 6.9e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 KND99506.1 - 2.7e-05 23.6 0.0 4.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.1 KND99506.1 - 0.015 14.7 0.0 0.04 13.4 0.0 1.4 1 1 0 1 1 1 0 Cupin-like domain Cupin_3 PF05899.7 KND99506.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF3667 PF12412.3 KND99506.1 - 0.098 11.9 0.1 0.17 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3667) Cupin_6 PF12852.2 KND99506.1 - 0.18 11.4 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 Cupin Kri1 PF05178.7 KND99506.1 - 0.25 11.6 4.0 0.5 10.6 2.8 1.5 1 0 0 1 1 1 0 KRI1-like family WD40 PF00400.27 KND99508.1 - 1.3e-45 151.6 8.3 9.6e-09 34.7 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KND99508.1 - 3.7e-05 23.5 0.9 0.065 12.9 0.1 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A 6PF2K PF01591.13 KND99510.1 - 3e-45 153.9 4.3 4.1e-45 153.5 3.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 KND99510.1 - 9.2e-15 54.7 0.2 1.5e-14 54.0 0.2 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KND99510.1 - 7e-08 31.9 0.1 1.4e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 KND99510.1 - 1.7e-06 28.8 0.0 2.8e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 KND99510.1 - 4.5e-05 23.1 0.0 9.7e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.1 KND99510.1 - 0.0002 21.6 0.0 0.0014 18.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KND99510.1 - 0.00036 20.6 0.0 0.001 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KND99510.1 - 0.0015 17.6 0.0 0.0037 16.3 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin MobB PF03205.9 KND99510.1 - 0.0016 18.1 0.0 0.0034 17.0 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 KND99510.1 - 0.0022 17.5 0.1 0.0052 16.3 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 KND99510.1 - 0.0063 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.15 KND99510.1 - 0.0076 14.9 0.0 0.0086 14.7 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit SRP54 PF00448.17 KND99510.1 - 0.0092 15.4 0.1 0.032 13.6 0.1 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.18 KND99510.1 - 0.012 15.5 0.4 0.033 14.1 0.0 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_25 PF13481.1 KND99510.1 - 0.02 14.3 0.1 0.041 13.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KND99510.1 - 0.022 15.0 0.1 0.032 14.5 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA PF00004.24 KND99510.1 - 0.035 14.3 0.7 0.96 9.6 0.5 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 KND99510.1 - 0.049 13.3 0.0 0.084 12.5 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_16 PF13191.1 KND99510.1 - 0.07 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 KND99510.1 - 0.081 12.6 0.0 3.2 7.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Pet127 PF08634.5 KND99511.1 - 1.6e-97 325.9 0.7 2.6e-97 325.2 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 DUF4146 PF13652.1 KND99511.1 - 0.0058 16.4 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4146) Hap4_Hap_bind PF10297.4 KND99512.1 - 1.1e-08 34.6 7.3 2.3e-08 33.6 5.1 1.6 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 KND99512.1 - 2e-06 27.6 14.1 0.00052 19.9 9.2 2.6 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 KND99512.1 - 0.0024 17.6 16.5 0.13 12.1 7.7 2.7 1 1 1 2 2 2 2 Basic region leucine zipper FliD_N PF02465.13 KND99512.1 - 0.48 10.8 8.1 20 5.6 5.6 3.0 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus NIF PF03031.13 KND99514.1 - 7e-40 136.2 0.1 1.3e-39 135.3 0.1 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ESSS PF10183.4 KND99514.1 - 0.12 12.8 0.0 0.12 12.8 0.0 2.0 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ZapA PF05164.8 KND99515.1 - 0.15 12.0 0.5 0.32 10.9 0.1 1.7 2 0 0 2 2 2 0 Cell division protein ZapA CDP-OH_P_transf PF01066.16 KND99516.1 - 3e-11 43.5 6.1 5e-11 42.7 4.2 1.5 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase RNA_pol_Rbc25 PF08292.7 KND99517.1 - 0.11 12.6 1.6 0.12 12.5 1.1 1.0 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 OAD_gamma PF04277.8 KND99517.1 - 0.84 10.0 2.5 0.89 9.9 1.7 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain BLVR PF06375.6 KND99517.1 - 3.4 7.4 9.4 3.2 7.5 6.5 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Peptidase_S49_N PF08496.5 KND99517.1 - 6.9 6.4 6.4 6.1 6.6 4.4 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RRP14 PF15459.1 KND99517.1 - 7.8 6.6 11.3 10 6.2 7.8 1.2 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 PH PF00169.24 KND99518.1 - 3.7e-08 33.5 3.4 5.8e-08 32.8 1.4 2.1 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KND99518.1 - 0.14 12.3 2.9 0.46 10.7 2.0 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain DNA_binding_1 PF01035.15 KND99523.1 - 7.2e-24 83.3 1.0 8.7e-24 83.0 0.1 1.6 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF3545 PF12065.3 KND99523.1 - 0.035 13.8 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) AA_permease PF00324.16 KND99524.1 - 3.1e-141 471.0 39.0 3.5e-141 470.8 27.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND99524.1 - 2.5e-42 144.9 41.3 2.9e-42 144.6 28.6 1.0 1 0 0 1 1 1 1 Amino acid permease PCI PF01399.22 KND99525.1 - 3.1e-06 27.4 0.8 1.4e-05 25.3 0.2 2.3 2 0 0 2 2 2 1 PCI domain Glyco_hydro_98C PF08307.6 KND99525.1 - 0.0014 17.9 0.2 0.0027 17.0 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 98 C-terminal domain PCI_Csn8 PF10075.4 KND99525.1 - 0.0019 18.0 0.6 0.0042 16.8 0.4 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Asp PF00026.18 KND99527.1 - 3.7e-54 184.1 1.3 4.2e-54 183.9 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 KND99527.1 - 0.001 18.6 0.1 0.0059 16.1 0.0 2.0 1 1 1 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 KND99527.1 - 0.038 13.9 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KND99527.1 - 0.098 13.1 0.0 23 5.5 0.0 3.0 2 1 0 2 2 2 0 Aspartyl protease V-ATPase_C PF03223.10 KND99529.1 - 1.2e-113 379.7 4.2 1.4e-113 379.6 2.9 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DUF2787 PF10980.3 KND99529.1 - 0.031 14.2 1.2 0.11 12.4 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2787) SURF6 PF04935.7 KND99530.1 - 1.6e-44 151.7 50.9 1.6e-44 151.7 35.3 2.1 2 0 0 2 2 2 1 Surfeit locus protein 6 PIP49_N PF14875.1 KND99530.1 - 1.9 8.1 4.4 0.33 10.6 0.2 1.8 2 0 0 2 2 2 0 N-term cysteine-rich ER, FAM69 TB2_DP1_HVA22 PF03134.14 KND99531.1 - 8.4e-32 108.7 2.2 1.2e-31 108.3 1.5 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Git3 PF11710.3 KND99531.1 - 0.059 12.9 8.4 0.08 12.4 5.5 1.5 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 SNN_transmemb PF09049.5 KND99531.1 - 7.9 6.2 6.0 1.7 8.4 0.9 2.1 2 0 0 2 2 2 0 Stannin transmembrane Adaptin_N PF01602.15 KND99532.1 - 1.4e-118 396.5 9.0 1.6e-118 396.3 6.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 KND99532.1 - 4e-16 59.3 0.1 9.5e-16 58.1 0.1 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Pro_isomerase PF00160.16 KND99533.1 - 3.1e-21 76.2 1.8 5.3e-21 75.4 0.1 2.0 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.20 KND99534.1 - 7.1e-45 153.1 0.0 1.2e-44 152.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND99534.1 - 3.7e-14 52.4 0.0 3.1e-13 49.3 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KND99534.1 - 0.0079 15.1 0.1 0.026 13.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like PsiB PF06290.6 KND99534.1 - 0.044 13.2 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) MerR_1 PF13411.1 KND99534.1 - 0.11 12.3 0.1 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 MerR HTH family regulatory protein Ribosomal_S14 PF00253.16 KND99536.1 - 1e-14 53.6 0.0 1.9e-13 49.5 0.0 2.0 2 0 0 2 2 2 2 Ribosomal protein S14p/S29e ADH_zinc_N PF00107.21 KND99537.1 - 9.3e-21 73.7 0.0 1.5e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KND99537.1 - 4e-05 24.5 0.0 9.8e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AMP-binding PF00501.23 KND99539.1 - 2.6e-42 144.7 0.0 3.2e-22 78.5 0.0 3.7 2 2 0 2 2 2 2 AMP-binding enzyme CRAL_TRIO PF00650.15 KND99541.1 - 3e-35 121.0 0.0 4.8e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KND99541.1 - 3.1e-09 36.9 0.0 6.8e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KND99541.1 - 1.6e-06 28.1 0.0 5.8e-06 26.3 0.0 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain PHD PF00628.24 KND99542.1 - 4.8e-09 35.7 2.6 4.8e-09 35.7 1.8 1.7 2 0 0 2 2 2 1 PHD-finger DUF1033 PF06279.6 KND99542.1 - 0.0078 16.0 0.1 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1033) PHD_2 PF13831.1 KND99542.1 - 0.24 10.7 4.4 0.41 10.0 3.0 1.4 1 0 0 1 1 1 0 PHD-finger Sec1 PF00995.18 KND99543.1 - 2.8e-120 402.6 23.4 3.3e-120 402.4 16.2 1.0 1 0 0 1 1 1 1 Sec1 family KRAB PF01352.22 KND99543.1 - 0.027 13.9 0.3 0.3 10.5 0.0 2.5 2 0 0 2 2 2 0 KRAB box Peptidase_M16 PF00675.15 KND99545.1 - 3.6e-42 143.6 0.1 5.1e-41 139.8 0.0 2.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KND99545.1 - 2.5e-23 82.7 0.6 5e-13 49.1 0.0 3.8 4 0 0 4 4 4 2 Peptidase M16 inactive domain Rogdi_lz PF10259.4 KND99546.1 - 7.2e-83 277.8 3.7 8.4e-83 277.6 2.6 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein HSP9_HSP12 PF04119.7 KND99546.1 - 0.0054 16.7 0.3 0.012 15.7 0.2 1.5 1 0 0 1 1 1 1 Heat shock protein 9/12 RNA_pol_Rpb1_5 PF04998.12 KND99546.1 - 0.055 12.7 0.0 0.07 12.3 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 PAS PF00989.19 KND99547.1 - 0.31 10.8 3.4 0.26 11.0 0.2 2.2 2 0 0 2 2 2 0 PAS fold Med15 PF09606.5 KND99547.1 - 1.4 6.9 49.6 0.78 7.8 5.0 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4557 PF15101.1 KND99547.1 - 4.5 7.0 15.7 8.5 6.1 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) CFEM PF05730.6 KND99549.1 - 5.8e-10 38.8 12.5 1.2e-09 37.8 8.7 1.6 1 0 0 1 1 1 1 CFEM domain DUF572 PF04502.8 KND99549.1 - 0.25 10.5 11.8 0.3 10.2 8.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF605 PF04652.11 KND99549.1 - 2.5 7.3 22.2 3.2 7.0 15.4 1.1 1 0 0 1 1 1 0 Vta1 like SOG2 PF10428.4 KND99549.1 - 4.2 5.9 22.8 5.1 5.6 15.8 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Amidohydro_1 PF01979.15 KND99551.1 - 2e-41 142.7 0.0 2.5e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KND99551.1 - 1.5e-07 30.9 0.3 0.00099 18.4 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KND99551.1 - 2.6e-05 24.4 0.0 0.04 13.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 KND99551.1 - 0.00012 21.7 0.0 0.00031 20.4 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 KND99551.1 - 0.00018 20.5 0.0 0.00031 19.7 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase NTF-like PF14540.1 KND99551.1 - 0.036 13.6 0.0 0.22 11.1 0.0 2.2 2 0 0 2 2 2 0 Nucleotidyltransferase-like SKG6 PF08693.5 KND99554.1 - 0.00021 20.5 0.4 0.00042 19.5 0.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 KND99554.1 - 0.066 12.6 2.0 0.085 12.3 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) PAP2 PF01569.16 KND99555.1 - 1.6e-20 73.1 3.6 1.6e-20 73.1 2.5 2.0 2 1 0 2 2 2 1 PAP2 superfamily 7tm_1 PF00001.16 KND99555.1 - 0.033 13.3 0.4 0.055 12.6 0.3 1.6 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) RDD PF06271.7 KND99555.1 - 2.1 8.2 6.6 0.73 9.7 0.0 2.6 2 2 1 3 3 3 0 RDD family DUF996 PF06195.8 KND99555.1 - 2.2 8.3 6.8 0.3 11.0 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF996) PAP2_C PF14360.1 KND99555.1 - 6.5 7.1 13.2 2.3 8.5 2.8 3.3 3 1 0 3 3 3 0 PAP2 superfamily C-terminal PSP1 PF04468.7 KND99556.1 - 1e-27 95.9 0.3 1e-27 95.9 0.2 1.7 2 0 0 2 2 2 1 PSP1 C-terminal conserved region Rad60-SLD PF11976.3 KND99558.1 - 1.7e-19 69.2 0.0 2e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KND99558.1 - 1.3e-08 34.0 0.0 1.7e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Vasohibin PF14822.1 KND99558.1 - 0.13 11.3 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Vasohibin TarH PF02203.10 KND99559.1 - 0.072 12.9 2.5 0.1 12.4 0.1 2.5 3 0 0 3 3 3 0 Tar ligand binding domain homologue NPV_P10 PF05531.7 KND99559.1 - 0.1 12.8 4.6 0.93 9.7 0.1 3.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Lip_A_acyltrans PF03279.8 KND99559.1 - 0.11 11.3 0.0 2.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial lipid A biosynthesis acyltransferase Tape_meas_lam_C PF09718.5 KND99559.1 - 0.85 9.5 6.7 0.61 10.0 1.7 2.9 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF948 PF06103.6 KND99559.1 - 2.1 8.2 11.7 0.073 12.9 0.4 3.8 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) MgsA_C PF12002.3 KND99560.1 - 2.5e-54 183.4 0.0 4.8e-54 182.5 0.0 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal RuvB_N PF05496.7 KND99560.1 - 5.9e-18 64.7 0.1 8.1e-17 61.0 0.1 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 KND99560.1 - 1e-17 64.5 0.0 2.3e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KND99560.1 - 1.1e-08 34.7 0.0 2.6e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.1 KND99560.1 - 2.2e-08 34.0 0.0 7.8e-08 32.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KND99560.1 - 1.1e-07 31.6 0.1 6e-07 29.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KND99560.1 - 5.1e-07 29.7 0.0 1.3e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 KND99560.1 - 6.6e-05 22.1 0.1 0.018 14.2 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 KND99560.1 - 0.00037 20.5 4.4 0.11 12.4 0.0 3.2 2 1 1 3 3 3 2 AAA ATPase domain AAA_3 PF07726.6 KND99560.1 - 0.0011 18.6 0.0 0.005 16.4 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KND99560.1 - 0.0019 18.3 4.1 0.012 15.7 0.3 3.1 3 1 0 3 3 2 1 AAA domain Viral_helicase1 PF01443.13 KND99560.1 - 0.0043 16.6 0.0 0.01 15.3 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 KND99560.1 - 0.0098 16.7 2.2 0.025 15.4 0.0 2.7 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 KND99560.1 - 0.018 14.4 0.0 0.043 13.2 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 KND99560.1 - 0.02 14.9 0.0 0.051 13.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 KND99560.1 - 0.026 14.8 0.1 0.17 12.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 KND99560.1 - 0.069 13.0 0.0 0.069 13.0 0.0 2.6 3 0 0 3 3 3 0 Shikimate kinase OGG_N PF07934.7 KND99563.1 - 1.4e-28 99.2 0.1 2.9e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 KND99563.1 - 3.2e-17 62.7 0.0 6e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KND99563.1 - 0.0047 16.5 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif LCD1 PF09798.4 KND99566.1 - 6.3e-101 338.3 15.9 8.1e-101 338.0 11.0 1.1 1 0 0 1 1 1 1 DNA damage checkpoint protein PAS_3 PF08447.6 KND99566.1 - 0.006 16.6 0.0 0.027 14.5 0.0 2.1 2 0 0 2 2 2 1 PAS fold TMF_TATA_bd PF12325.3 KND99566.1 - 0.073 12.7 6.2 0.7 9.6 2.4 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 KND99566.1 - 0.69 9.4 4.3 1 8.9 0.7 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF4140 PF13600.1 KND99566.1 - 1.7 9.1 5.7 6.6 7.2 0.5 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) EMG1 PF03587.9 KND99567.1 - 9.2e-78 260.1 0.0 1.1e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Cyclin_N PF00134.18 KND99568.1 - 3.3e-12 46.0 0.9 6e-12 45.2 0.6 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 KND99568.1 - 0.0083 15.9 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Pkinase PF00069.20 KND99569.1 - 6.5e-72 241.7 0.0 1.3e-71 240.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND99569.1 - 7.6e-36 123.5 0.0 1.2e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND99569.1 - 9.4e-05 21.5 0.0 0.00018 20.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KND99569.1 - 0.073 12.7 2.5 0.078 12.7 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF501 PF04417.7 KND99569.1 - 0.86 9.4 3.7 0.81 9.5 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF501) Prenyltransf PF01255.14 KND99572.1 - 2.6e-77 258.9 0.1 3.4e-77 258.5 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase SHP PF03579.8 KND99572.1 - 0.06 12.7 0.5 0.12 11.6 0.4 1.5 1 0 0 1 1 1 0 Small hydrophobic protein HisG PF01634.13 KND99573.1 - 2.8e-38 131.0 0.1 3.7e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 KND99573.1 - 3.1e-26 91.0 0.0 5e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 KND99573.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 NMT1/THI5 like PCI PF01399.22 KND99574.1 - 1.2e-14 54.4 0.6 5.4e-14 52.3 0.4 2.2 1 0 0 1 1 1 1 PCI domain HTH_Crp_2 PF13545.1 KND99574.1 - 0.02 14.6 0.2 0.56 10.0 0.0 2.7 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Glyco_hydro_72 PF03198.9 KND99575.1 - 6.7e-132 439.2 4.4 8.7e-132 438.8 3.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase T4SS-DNA_transf PF02534.9 KND99575.1 - 0.059 11.9 1.1 0.098 11.2 0.7 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.2 KND99575.1 - 0.067 13.0 3.3 0.14 11.9 2.3 1.5 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG Adap_comp_sub PF00928.16 KND99577.1 - 5.7e-86 287.8 0.5 7.5e-86 287.4 0.3 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KND99577.1 - 4.8e-08 32.8 3.5 7.3e-08 32.2 2.0 1.7 1 1 1 2 2 2 1 Clathrin adaptor complex small chain DUF2458 PF10454.4 KND99578.1 - 3.7e-15 56.0 3.0 3.7e-15 56.0 2.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF2458) Globin PF00042.17 KND99578.1 - 0.019 15.3 0.3 10 6.4 0.0 2.6 2 1 0 2 2 2 0 Globin Selenoprotein_S PF06936.6 KND99578.1 - 0.07 12.6 1.7 0.12 11.8 1.2 1.5 1 0 0 1 1 1 0 Selenoprotein S (SelS) Pescadillo_N PF06732.6 KND99578.1 - 0.095 11.9 5.0 0.78 8.9 1.9 2.1 1 1 1 2 2 2 0 Pescadillo N-terminus CorA PF01544.13 KND99578.1 - 0.2 10.6 6.7 0.3 10.1 4.7 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein RFX_DNA_binding PF02257.10 KND99579.1 - 2.2e-11 43.7 1.0 3.6e-10 39.8 0.7 2.5 1 1 0 1 1 1 1 RFX DNA-binding domain NYD-SP28_assoc PF14775.1 KND99579.1 - 0.07 12.8 0.1 0.25 11.0 0.1 1.9 1 0 0 1 1 1 0 Sperm tail C-terminal domain PCNA_N PF00705.13 KND99580.1 - 2.7e-47 159.4 6.5 2e-46 156.6 2.0 2.7 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 KND99580.1 - 4.9e-47 159.0 0.0 8.5e-47 158.2 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 KND99580.1 - 4.3e-06 26.0 0.1 5e-06 25.8 0.1 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 KND99580.1 - 0.00042 19.3 0.0 0.072 12.0 0.0 2.1 2 0 0 2 2 2 2 Hus1-like protein Phyto-Amp PF15438.1 KND99580.1 - 0.012 15.2 0.3 0.078 12.6 0.0 2.1 2 0 0 2 2 2 0 Antigenic membrane protein of phytoplasma DUF229 PF02995.12 KND99580.1 - 0.074 11.4 0.0 0.11 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) PCNA_N PF00705.13 KND99581.1 - 1.7e-28 98.6 0.9 1.9e-28 98.5 0.6 1.0 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Oxysterol_BP PF01237.13 KND99582.1 - 3.7e-105 351.2 0.6 5.9e-105 350.6 0.4 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 KND99582.1 - 1.5e-35 121.1 0.8 3.9e-35 119.7 0.5 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain EMP24_GP25L PF01105.19 KND99582.1 - 0.019 14.6 1.0 0.45 10.2 0.0 2.8 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD C1q PF00386.16 KND99582.1 - 0.054 13.5 0.1 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 C1q domain PH PF00169.24 KND99582.1 - 0.13 12.4 4.1 0.31 11.2 1.1 3.0 2 1 0 2 2 2 0 PH domain zf-RING_UBOX PF13445.1 KND99583.1 - 6.6e-08 32.1 6.6 2.5e-07 30.3 4.5 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 KND99583.1 - 3e-07 29.9 8.3 3e-07 29.9 5.8 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KND99583.1 - 3.2e-07 30.0 6.3 3.2e-07 30.0 4.3 3.1 3 1 0 3 3 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KND99583.1 - 3.6e-07 30.0 8.2 3.6e-07 30.0 5.7 3.0 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KND99583.1 - 1e-05 25.1 6.7 1e-05 25.1 4.7 2.8 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KND99583.1 - 1e-05 25.2 8.8 1e-05 25.2 6.1 2.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KND99583.1 - 3.3e-05 23.4 4.8 3.3e-05 23.4 3.3 3.1 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 KND99583.1 - 0.00097 18.6 4.3 0.00097 18.6 3.0 2.6 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Sina PF03145.11 KND99583.1 - 0.039 13.6 9.5 0.54 9.8 2.0 2.3 2 0 0 2 2 2 0 Seven in absentia protein family Epsilon_antitox PF08998.6 KND99583.1 - 0.092 12.7 0.2 4 7.4 0.0 2.5 2 0 0 2 2 2 0 Bacterial epsilon antitoxin TSC22 PF01166.13 KND99583.1 - 0.37 10.7 3.0 1.9 8.5 0.2 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family zf-TRAF PF02176.13 KND99583.1 - 0.37 11.2 33.0 0.33 11.3 0.5 4.7 2 1 2 4 4 4 0 TRAF-type zinc finger zf-RING_4 PF14570.1 KND99583.1 - 8.3 6.0 16.6 4 7.0 1.2 4.0 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain MAGE PF01454.14 KND99584.1 - 1.6e-10 40.6 0.2 2.7e-10 39.8 0.1 1.5 1 1 0 1 1 1 1 MAGE family FAD_binding_1 PF00667.15 KND99585.1 - 2.2e-65 220.1 0.0 3.5e-65 219.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KND99585.1 - 7.6e-33 113.5 1.1 1.6e-32 112.4 0.8 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KND99585.1 - 6.2e-20 71.8 0.0 1.8e-19 70.2 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Ins_P5_2-kin PF06090.7 KND99586.1 - 1.6e-45 155.5 0.0 1.9e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase AIM24 PF01987.12 KND99587.1 - 0.00036 20.0 0.1 0.015 14.8 0.0 2.6 1 1 1 2 2 2 2 Mitochondrial biogenesis AIM24 MKT1_C PF12246.3 KND99588.1 - 4.8e-37 127.2 0.9 2e-36 125.2 0.1 2.1 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 KND99588.1 - 2.9e-25 88.3 0.0 7.5e-25 87.0 0.0 1.8 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 KND99588.1 - 3.6e-12 46.4 0.0 2.9e-10 40.2 0.0 2.7 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 KND99588.1 - 1.7e-11 43.9 0.0 4.1e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 XPG I-region UbiA PF01040.13 KND99590.1 - 2.4e-23 82.6 12.3 2.4e-23 82.6 8.5 1.7 1 1 1 2 2 2 1 UbiA prenyltransferase family 5TM-5TMR_LYT PF07694.7 KND99590.1 - 0.096 12.0 4.1 0.98 8.7 0.1 2.5 2 0 0 2 2 2 0 5TMR of 5TMR-LYT MitMem_reg PF13012.1 KND99591.1 - 6.8e-37 126.0 0.5 1.9e-36 124.6 0.2 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KND99591.1 - 8.1e-29 99.6 0.0 1.4e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF2999 PF11212.3 KND99591.1 - 0.1 12.6 0.0 0.36 10.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) ATP_bind_1 PF03029.12 KND99592.1 - 5.5e-66 222.5 0.0 6.4e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 KND99592.1 - 8.2e-05 22.5 0.0 0.00017 21.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KND99592.1 - 0.00054 19.4 0.0 0.0011 18.4 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain MipZ PF09140.6 KND99592.1 - 0.00097 18.2 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ArgK PF03308.11 KND99592.1 - 0.0016 17.3 0.0 0.0025 16.6 0.0 1.2 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 KND99592.1 - 0.0032 16.9 0.0 0.0066 15.8 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 KND99592.1 - 0.0045 16.7 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KND99592.1 - 0.0045 17.2 1.4 0.27 11.5 0.2 2.7 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KND99592.1 - 0.0052 16.7 0.0 0.026 14.4 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KND99592.1 - 0.0055 17.5 1.6 0.012 16.4 0.3 2.3 2 2 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 KND99592.1 - 0.0067 15.8 0.0 0.018 14.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_19 PF13245.1 KND99592.1 - 0.009 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain KTI12 PF08433.5 KND99592.1 - 0.04 13.1 0.0 0.074 12.2 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_29 PF13555.1 KND99592.1 - 0.046 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KND99592.1 - 0.071 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KND99592.1 - 0.087 12.5 0.0 0.65 9.6 0.0 2.1 2 0 0 2 2 2 0 NTPase AAA_16 PF13191.1 KND99592.1 - 0.092 12.7 0.0 0.3 11.0 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 KND99592.1 - 0.1 12.7 0.0 0.41 10.8 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Prefoldin PF02996.12 KND99593.1 - 0.0097 15.5 0.0 0.069 12.8 0.0 2.5 1 1 0 1 1 1 1 Prefoldin subunit Thioredox_DsbH PF03190.10 KND99594.1 - 0.074 12.7 0.0 0.097 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF255 AA_permease PF00324.16 KND99595.1 - 5.2e-114 381.2 37.6 6.4e-114 380.9 26.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KND99595.1 - 1.2e-32 113.0 37.7 1.5e-32 112.7 26.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF106 PF01956.11 KND99595.1 - 1 8.8 0.0 1 8.8 0.0 3.5 3 1 1 4 4 4 0 Integral membrane protein DUF106 Hyphal_reg_CWP PF11765.3 KND99597.1 - 2.3e-54 184.4 13.3 6.6e-54 182.9 9.2 1.8 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal DUF2606 PF10794.4 KND99597.1 - 0.018 14.4 24.1 14 5.1 0.1 10.1 11 1 0 12 12 12 0 Protein of unknown function (DUF2606) PPV_E2_C PF00511.12 KND99597.1 - 3.8 7.5 121.4 2.1 8.3 0.8 17.4 7 5 9 17 17 17 0 E2 (early) protein, C terminal TFR_dimer PF04253.10 KND99598.1 - 8.2e-16 57.7 0.3 3.1e-15 55.8 0.2 1.9 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KND99598.1 - 3.1e-15 56.3 0.0 6.2e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KND99598.1 - 1.4e-08 34.3 0.1 8.5e-08 31.8 0.0 2.3 3 0 0 3 3 3 1 PA domain DUF1411 PF07199.6 KND99598.1 - 0.16 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) Aldedh PF00171.17 KND99599.1 - 9.9e-177 587.8 0.9 1.1e-176 587.7 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Sec16 PF12932.2 KND99599.1 - 0.096 12.6 0.1 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region TrbC_Ftype PF09673.5 KND99600.1 - 0.033 13.7 0.0 0.037 13.6 0.0 1.0 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein Asp PF00026.18 KND99601.1 - 4.1e-62 210.2 0.2 4.8e-62 210.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KND99601.1 - 1.2e-08 35.1 0.0 1.5e-07 31.5 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KND99601.1 - 0.0015 19.0 0.1 2.1 8.9 0.0 3.6 3 1 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.1 KND99601.1 - 0.14 11.7 0.1 1.3 8.5 0.0 2.4 1 1 1 2 2 2 0 Xylanase inhibitor C-terminal FMN_dh PF01070.13 KND99602.1 - 2.7e-116 388.2 0.0 3.6e-116 387.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 KND99602.1 - 3.2e-06 26.5 0.0 6.1e-05 22.3 0.0 2.4 2 1 1 3 3 3 1 Histidine biosynthesis protein IMPDH PF00478.20 KND99602.1 - 4.3e-06 25.8 0.1 1.6e-05 23.9 0.1 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KND99602.1 - 9.5e-06 24.9 0.3 1.6e-05 24.2 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 KND99602.1 - 4.6e-05 22.5 0.0 0.00011 21.3 0.0 1.6 1 1 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 KND99602.1 - 0.00011 21.3 0.6 0.12 11.4 0.0 2.3 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG Aa_trans PF01490.13 KND99604.1 - 8.9e-25 87.0 34.8 7.9e-24 83.8 20.7 2.1 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KND99604.1 - 0.037 12.8 30.0 0.11 11.3 19.0 2.4 1 1 1 2 2 2 0 Tryptophan/tyrosine permease family DUF3040 PF11239.3 KND99604.1 - 0.61 10.1 0.0 0.61 10.1 0.0 4.7 3 3 4 7 7 7 0 Protein of unknown function (DUF3040) DUF1129 PF06570.6 KND99604.1 - 9.2 5.5 14.2 7.5 5.8 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Aa_trans PF01490.13 KND99605.1 - 1.4e-20 73.1 41.7 2.5e-19 69.0 28.9 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KND99605.1 - 7.3e-05 21.7 17.0 7.3e-05 21.7 11.8 3.3 1 1 1 3 3 3 2 Tryptophan/tyrosine permease family DUF1980 PF09323.5 KND99605.1 - 0.58 9.8 3.2 2.7 7.7 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) COX4_pro_2 PF07835.7 KND99605.1 - 5.3 7.0 11.2 1.7 8.6 1.2 3.5 3 0 0 3 3 3 0 Bacterial aa3 type cytochrome c oxidase subunit IV NAD_binding_10 PF13460.1 KND99606.1 - 5.7e-13 49.2 0.1 7.5e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KND99606.1 - 1.6e-09 37.3 0.0 5.1e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 KND99606.1 - 2.7e-07 30.2 0.0 6.7e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KND99606.1 - 0.00086 19.6 0.1 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KND99606.1 - 0.0016 17.2 0.0 0.026 13.2 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 KND99606.1 - 0.003 17.4 0.1 0.0058 16.5 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.12 KND99606.1 - 0.0048 15.8 0.1 0.27 10.0 0.0 2.3 2 1 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.20 KND99606.1 - 0.0056 16.6 0.0 0.0096 15.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase YjeF_N PF03853.10 KND99606.1 - 0.013 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus 3HCDH_N PF02737.13 KND99606.1 - 0.027 14.1 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 KND99606.1 - 0.037 13.8 0.4 0.074 12.8 0.3 1.6 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KND99606.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Fungal_trans PF04082.13 KND99607.1 - 3.5e-29 101.4 2.0 6e-29 100.6 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DHDPS PF00701.17 KND99608.1 - 4.1e-64 215.9 0.0 4.7e-64 215.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.1 KND99608.1 - 1.5e-06 27.5 0.0 2.1e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Aa_trans PF01490.13 KND99610.1 - 6.9e-27 93.9 29.7 9e-27 93.5 20.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KND99610.1 - 0.00018 20.4 19.3 0.00018 20.4 13.4 2.3 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.1 KND99610.1 - 0.41 9.1 48.1 0.093 11.2 18.7 2.1 1 1 1 2 2 2 0 Amino acid permease MFS_1 PF07690.11 KND99612.1 - 6.8e-16 57.9 39.8 6.1e-09 35.0 17.6 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 KND99612.1 - 0.0009 17.7 39.9 0.0079 14.6 11.3 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein Conotoxin PF02950.12 KND99612.1 - 0.17 12.7 0.1 0.17 12.7 0.1 2.3 2 0 0 2 2 2 0 Conotoxin DUF1418 PF07214.7 KND99612.1 - 1.3 8.7 5.4 3.8 7.1 1.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) TP_methylase PF00590.15 KND99613.1 - 1.9e-21 76.7 0.1 2.9e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Per1 PF04080.8 KND99614.1 - 1.3e-90 303.4 12.7 1.3e-90 303.4 8.8 1.6 2 0 0 2 2 2 1 Per1-like Kelch_2 PF07646.10 KND99614.1 - 0.3 10.9 1.7 0.75 9.6 1.1 1.7 1 0 0 1 1 1 0 Kelch motif Aldolase_II PF00596.16 KND99615.1 - 3.4e-47 160.4 0.1 4.2e-47 160.1 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Asp PF00026.18 KND99617.1 - 2.1e-62 211.2 7.5 2.7e-62 210.8 5.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KND99617.1 - 0.00017 21.5 0.0 0.0007 19.5 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal DUF669 PF05037.8 KND99617.1 - 0.024 14.5 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF669) TAXi_C PF14541.1 KND99617.1 - 0.058 12.9 0.0 0.35 10.4 0.0 2.0 1 1 1 2 2 2 0 Xylanase inhibitor C-terminal MFS_1 PF07690.11 KND99618.1 - 4.6e-18 65.0 36.9 4.1e-12 45.4 15.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND99618.1 - 5.4e-06 25.2 9.2 5.4e-06 25.2 6.3 3.4 1 1 0 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 KND99618.1 - 0.00017 20.0 35.6 0.0058 15.0 4.5 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein RNA_pol_N PF01194.12 KND99620.1 - 0.071 13.1 1.6 0.74 9.8 0.1 2.2 2 0 0 2 2 2 0 RNA polymerases N / 8 kDa subunit Ferric_reduct PF01794.14 KND99621.1 - 6.1e-14 52.1 9.3 6.1e-14 52.1 6.5 2.9 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KND99621.1 - 5.3e-11 42.6 0.0 1.6e-10 41.1 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KND99621.1 - 1.7e-09 37.5 0.8 1.1e-08 34.9 0.0 2.4 2 0 0 2 2 2 1 FAD-binding domain PTCB-BRCT PF12738.2 KND99622.1 - 0.69 9.8 6.8 0.81 9.5 0.2 2.7 2 1 1 3 3 3 0 twin BRCT domain Arrestin_N PF00339.24 KND99623.1 - 6.1e-11 42.3 0.4 1.2e-09 38.1 0.0 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KND99623.1 - 0.0063 16.6 0.9 4.5 7.3 0.0 2.8 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.10 KND99623.1 - 0.0074 15.0 0.0 0.015 14.1 0.0 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 polyprenyl_synt PF00348.12 KND99624.1 - 6.4e-38 130.0 0.0 1e-37 129.4 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Rhabdo_ncap PF00945.13 KND99624.1 - 0.093 11.2 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DER1 PF04511.10 KND99625.1 - 4.2e-11 42.7 12.0 9.3e-11 41.5 5.3 2.4 1 1 1 2 2 2 2 Der1-like family DUF621 PF04789.10 KND99625.1 - 0.3 10.0 0.1 0.3 10.0 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF621) YqzE PF14038.1 KND99626.1 - 7.4 6.4 8.0 8.2 6.2 5.6 1.2 1 0 0 1 1 1 0 YqzE-like protein VPS9 PF02204.13 KND99627.1 - 1.7e-12 47.2 10.0 1.5e-08 34.5 0.2 4.3 5 1 0 5 5 5 2 Vacuolar sorting protein 9 (VPS9) domain DUF87 PF01935.12 KND99628.1 - 0.0023 17.7 0.4 0.0055 16.5 0.2 1.6 1 1 0 1 1 1 1 Domain of unknown function DUF87 DUF1456 PF07308.8 KND99628.1 - 0.073 13.1 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) SH2_2 PF14633.1 KND99629.1 - 2.4e-70 236.0 0.9 2.4e-70 236.0 0.6 2.1 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 KND99629.1 - 7.4e-34 116.2 2.2 7.4e-34 116.2 1.5 3.5 3 0 0 3 3 3 1 Death-like domain of SPT6 YqgF PF14639.1 KND99629.1 - 3e-31 108.0 0.0 1.1e-30 106.1 0.0 2.1 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 KND99629.1 - 2e-30 104.9 0.0 4.7e-30 103.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.1 KND99629.1 - 5.4e-24 84.1 24.2 5.4e-24 84.1 16.8 5.6 4 1 2 6 6 6 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 KND99629.1 - 3.2e-23 81.9 1.3 3.2e-23 81.9 0.9 2.6 3 0 0 3 3 3 1 Helix-turn-helix DNA-binding domain of SPT6 TauD PF02668.11 KND99630.1 - 4.1e-59 200.3 0.0 5.7e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KND99630.1 - 0.007 15.2 0.0 0.016 14.1 0.0 1.5 1 0 0 1 1 1 1 CsiD DUF1212 PF06738.7 KND99631.1 - 2.9e-50 170.4 11.7 1.4e-48 164.9 0.1 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KND99631.1 - 9.3e-23 80.5 9.7 9.3e-23 80.5 6.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) TT_ORF1 PF02956.9 KND99632.1 - 1 7.7 9.7 0.99 7.7 6.7 1.0 1 0 0 1 1 1 0 TT viral orf 1 PDCD2_C PF04194.8 KND99633.1 - 1e-35 122.7 0.1 1e-35 122.7 0.1 2.9 3 1 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain DUF3490 PF11995.3 KND99633.1 - 0.2 11.1 1.0 0.73 9.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3490) GTP_EFTU PF00009.22 KND99634.1 - 7.3e-37 126.6 3.2 7.3e-37 126.6 2.2 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KND99634.1 - 4.3e-25 87.7 0.9 1.5e-24 85.9 0.6 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 IF2_N PF04760.10 KND99634.1 - 5.8e-10 38.6 0.0 1.3e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region GTP_EFTU_D2 PF03144.20 KND99634.1 - 6.2e-10 39.0 1.8 1.3e-06 28.3 0.0 3.3 3 0 0 3 3 3 2 Elongation factor Tu domain 2 Miro PF08477.8 KND99634.1 - 3.7e-06 27.4 1.6 8.7e-06 26.2 0.1 2.5 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KND99634.1 - 1.1e-05 25.3 2.0 1.1e-05 25.3 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KND99634.1 - 0.00066 18.9 0.8 0.0017 17.6 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 KND99634.1 - 0.0078 15.4 0.0 0.0078 15.4 0.0 2.0 3 0 0 3 3 3 1 ADP-ribosylation factor family MS_channel PF00924.13 KND99634.1 - 0.024 13.9 2.3 0.12 11.6 0.7 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel DUF4476 PF14771.1 KND99634.1 - 0.039 13.9 0.1 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) Ndc1_Nup PF09531.5 KND99634.1 - 0.063 11.6 2.1 0.084 11.2 1.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ras PF00071.17 KND99634.1 - 0.092 12.1 0.1 0.092 12.1 0.1 1.9 2 0 0 2 2 2 0 Ras family SRPRB PF09439.5 KND99634.1 - 0.64 9.2 7.5 0.043 13.0 0.4 2.5 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_23 PF13476.1 KND99634.1 - 9.5 6.4 0.0 9.5 6.4 0.0 3.7 4 1 0 4 4 3 0 AAA domain Dfp1_Him1_M PF08630.5 KND99635.1 - 7.4e-36 122.6 0.0 1.8e-35 121.4 0.0 1.7 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 KND99635.1 - 3.1e-24 84.3 1.9 6.3e-24 83.3 1.3 1.5 1 0 0 1 1 1 1 DBF zinc finger UQ_con PF00179.21 KND99637.1 - 1.1e-41 141.5 0.0 1.4e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KND99637.1 - 0.0062 16.2 0.0 0.022 14.5 0.0 1.8 1 1 0 1 1 1 1 Prokaryotic E2 family B BTK PF00779.14 KND99637.1 - 0.16 11.5 0.3 0.83 9.3 0.0 2.1 2 0 0 2 2 2 0 BTK motif SH3BGR PF04908.10 KND99640.1 - 2.6e-07 30.4 0.1 3.6e-06 26.8 0.0 3.2 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 KND99640.1 - 0.0088 16.0 0.0 0.0088 16.0 0.0 3.6 4 0 0 4 4 4 1 Glutaredoxin ETRAMP PF09716.5 KND99640.1 - 5.7 6.9 5.6 10 6.1 0.9 3.7 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) KH_1 PF00013.24 KND99641.1 - 3.3e-72 238.0 22.2 1e-10 41.0 0.1 9.6 9 0 0 9 9 9 8 KH domain KH_3 PF13014.1 KND99641.1 - 1.7e-41 139.2 12.8 8.8e-07 28.4 0.0 9.1 8 0 0 8 8 8 7 KH domain KH_4 PF13083.1 KND99641.1 - 8.4e-06 25.3 2.5 0.033 13.8 0.1 5.4 4 1 0 4 4 4 1 KH domain KH_2 PF07650.12 KND99641.1 - 0.0057 16.1 22.3 2 8.0 0.2 7.0 7 1 0 7 7 7 4 KH domain Ribosomal_S10 PF00338.17 KND99641.1 - 0.027 14.3 1.5 0.12 12.1 0.0 3.0 3 0 0 3 3 3 0 Ribosomal protein S10p/S20e AA_permease_2 PF13520.1 KND99642.1 - 1e-89 301.0 46.5 1.4e-89 300.6 32.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KND99642.1 - 5.8e-20 71.0 37.5 1e-19 70.2 26.0 1.3 1 1 0 1 1 1 1 Amino acid permease L51_S25_CI-B8 PF05047.11 KND99643.1 - 9.3e-06 25.2 0.0 1.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain PH_11 PF15413.1 KND99643.1 - 0.052 13.8 0.2 0.07 13.3 0.1 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain Zn_clus PF00172.13 KND99645.1 - 4.1e-05 23.3 9.8 4.1e-05 23.3 6.8 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 KND99645.1 - 1.1 9.4 10.8 2.9 8.1 7.5 1.7 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region zinc_ribbon_6 PF14599.1 KND99645.1 - 1.4 8.7 7.0 1.5 8.6 3.8 1.8 1 1 1 2 2 2 0 Zinc-ribbon TauD PF02668.11 KND99646.1 - 8.5e-55 186.1 0.9 1e-54 185.9 0.6 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TauD PF02668.11 KND99647.1 - 3.2e-51 174.4 2.4 5.6e-51 173.6 1.6 1.4 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family EF-hand_4 PF12763.2 KND99648.1 - 4.9e-24 84.0 0.0 4.2e-12 45.7 0.0 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand UBA PF00627.26 KND99648.1 - 3.2e-09 36.3 0.2 1.1e-08 34.6 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.27 KND99648.1 - 0.00065 18.8 0.1 0.62 9.5 0.0 3.5 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 KND99648.1 - 0.0026 17.8 0.0 0.3 11.2 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain pair CUE PF02845.11 KND99648.1 - 0.011 15.1 0.1 0.047 13.2 0.0 2.1 2 0 0 2 2 2 0 CUE domain DUF3584 PF12128.3 KND99648.1 - 0.049 10.9 31.8 0.08 10.2 22.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) EF-hand_6 PF13405.1 KND99648.1 - 0.066 13.1 0.1 1.2 9.2 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain TPR_MLP1_2 PF07926.7 KND99648.1 - 0.66 9.7 44.1 0.063 13.0 13.3 4.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 KND99648.1 - 0.82 8.7 20.4 0.039 13.1 6.5 2.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 KND99648.1 - 7.8 6.3 40.7 10 5.9 13.5 3.4 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Gar1 PF04410.9 KND99650.1 - 4.4e-45 152.9 0.1 4.4e-45 152.9 0.0 1.9 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region MMR_HSR1 PF01926.18 KND99651.1 - 3.7e-12 46.2 0.0 6.4e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KND99651.1 - 8.7e-06 25.2 0.1 7.7e-05 22.1 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KND99651.1 - 8.1e-05 22.5 0.0 0.14 11.9 0.0 2.4 2 0 0 2 2 2 2 Dynamin family SRPRB PF09439.5 KND99651.1 - 0.00041 19.6 0.0 0.00068 18.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 KND99651.1 - 0.0012 18.0 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KND99651.1 - 0.0022 17.1 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.22 KND99651.1 - 0.0071 16.6 0.0 0.012 15.9 0.0 1.7 1 1 0 1 1 1 1 ABC transporter FeoB_N PF02421.13 KND99651.1 - 0.018 14.2 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.13 KND99651.1 - 0.019 14.0 0.0 0.049 12.6 0.0 1.6 1 1 0 1 1 1 0 Septin Gtr1_RagA PF04670.7 KND99651.1 - 0.027 13.5 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 KND99651.1 - 0.07 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 KND99651.1 - 0.084 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain VanZ PF04892.7 KND99652.1 - 1.5e-05 24.9 0.0 1.8e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 VanZ like family PLDc PF00614.17 KND99653.1 - 2.4e-17 62.1 0.6 2.6e-07 30.2 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KND99653.1 - 1.3e-12 47.5 0.1 7.7e-08 32.1 0.0 2.9 2 0 0 2 2 2 2 PLD-like domain Erv26 PF04148.8 KND99654.1 - 7.8e-77 257.3 11.8 1.8e-76 256.2 8.2 1.4 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 BCCT PF02028.12 KND99654.1 - 0.0013 17.0 0.5 0.0019 16.5 0.4 1.4 1 0 0 1 1 1 1 BCCT family transporter Cyto_ox_2 PF02322.10 KND99654.1 - 0.027 13.6 1.2 0.034 13.3 0.8 1.2 1 0 0 1 1 1 0 Cytochrome oxidase subunit II DUF2909 PF11137.3 KND99654.1 - 0.06 13.0 0.3 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) DUF2189 PF09955.4 KND99654.1 - 0.11 12.4 2.3 2 8.3 1.6 2.4 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2189) Abhydrolase_1 PF00561.15 KND99655.1 - 3.3e-19 69.3 0.1 1.4e-18 67.3 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KND99655.1 - 1.8e-09 37.8 0.0 5.5e-09 36.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KND99655.1 - 2.5e-05 23.8 0.0 4.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KND99655.1 - 0.1 12.3 0.0 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KND99655.1 - 0.11 11.6 0.0 0.34 10.1 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Scs3p PF10261.4 KND99656.1 - 1.6e-21 76.4 6.2 1.2e-20 73.6 4.3 2.3 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PP2C PF00481.16 KND99657.1 - 5.5e-64 216.0 0.1 8.5e-63 212.1 0.1 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C E1-E2_ATPase PF00122.15 KND99658.1 - 1.2e-52 178.1 1.6 2.6e-52 177.1 1.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KND99658.1 - 5.1e-36 123.9 6.1 5.1e-36 123.9 4.2 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KND99658.1 - 9.1e-29 101.4 0.0 5.6e-28 98.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KND99658.1 - 2.1e-16 60.6 0.4 6.6e-16 59.0 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KND99658.1 - 1.6e-13 50.4 0.0 3.9e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KND99658.1 - 1.2e-08 34.2 0.0 6.3e-08 31.9 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KND99658.1 - 0.0064 16.0 0.5 0.031 13.8 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Abhydrolase_6 PF12697.2 KND99660.1 - 1.1e-23 84.3 0.0 1.2e-23 84.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KND99660.1 - 1.4e-18 67.0 0.0 3e-18 65.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KND99660.1 - 1.3e-16 60.1 0.0 2.7e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 KND99660.1 - 9.7e-11 41.6 0.0 1.6e-10 40.9 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KND99660.1 - 4.4e-06 26.0 0.0 0.041 13.1 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KND99660.1 - 0.00044 19.7 0.0 0.33 10.3 0.0 2.6 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Esterase PF00756.15 KND99660.1 - 0.00061 19.2 0.0 0.0014 18.0 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.2 KND99660.1 - 0.0083 15.0 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KND99660.1 - 0.037 12.8 0.0 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DDE_1 PF03184.14 KND99661.1 - 4.4e-35 120.8 0.0 2e-34 118.6 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 KND99661.1 - 3.4e-13 49.1 0.3 3.4e-13 49.1 0.2 2.7 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain PEP-utilisers_N PF05524.8 KND99662.1 - 0.029 14.1 0.2 0.03 14.1 0.1 1.0 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal FeoA PF04023.9 KND99662.1 - 0.13 12.2 0.2 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 FeoA domain Cwf_Cwc_15 PF04889.7 KND99662.1 - 0.44 10.2 3.5 0.47 10.1 2.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF846 PF05832.7 KND99663.1 - 1.6e-52 177.0 11.6 1.9e-52 176.7 8.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Clathrin PF00637.15 KND99664.1 - 1.8e-25 89.2 2.6 1.8e-25 89.2 1.8 2.2 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 KND99664.1 - 0.001 18.8 0.1 0.0026 17.5 0.1 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat Vps39_1 PF10366.4 KND99664.1 - 0.0045 16.9 0.1 0.0045 16.9 0.1 2.9 3 1 1 4 4 4 1 Vacuolar sorting protein 39 domain 1 Tbf5 PF06331.7 KND99665.1 - 1.3e-25 88.9 0.2 1.4e-25 88.8 0.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 EppA_BapA PF07268.6 KND99665.1 - 0.04 13.5 0.0 0.046 13.3 0.0 1.0 1 0 0 1 1 1 0 Exported protein precursor (EppA/BapA) Sec34 PF04136.10 KND99666.1 - 1.8e-23 83.0 3.3 7.8e-23 80.9 2.3 2.1 1 0 0 1 1 1 1 Sec34-like family CheX PF13690.1 KND99666.1 - 0.071 12.9 0.2 0.22 11.4 0.1 1.9 1 1 0 1 1 1 0 Chemotaxis phosphatase CheX zf-primase PF09329.6 KND99667.1 - 5.9e-13 48.1 1.0 1.4e-12 46.9 0.7 1.6 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.20 KND99667.1 - 0.00056 19.7 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain p450 PF00067.17 KND99669.1 - 2.5e-62 210.9 0.0 3.2e-62 210.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UPF0160 PF03690.8 KND99670.1 - 1.4e-124 415.6 0.0 1.6e-124 415.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) AP_endonuc_2_N PF07582.7 KND99671.1 - 0.026 14.0 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus DUF1774 PF08611.5 KND99672.1 - 3.3e-29 100.8 3.5 3.3e-29 100.8 2.4 2.4 3 0 0 3 3 3 1 Fungal protein of unknown function (DUF1774) Pyridoxal_deC PF00282.14 KND99673.1 - 6.6e-60 202.5 0.0 9.2e-60 202.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KND99673.1 - 3.3e-06 26.0 0.0 5.4e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V UAA PF08449.6 KND99676.1 - 1.6e-11 43.6 16.0 2.2e-11 43.2 11.1 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KND99676.1 - 3e-10 39.9 7.1 3e-10 39.9 5.0 2.9 2 1 0 2 2 2 1 Triose-phosphate Transporter family PHO4 PF01384.15 KND99676.1 - 0.00075 18.2 2.6 0.00075 18.2 1.8 2.2 2 1 0 2 2 2 1 Phosphate transporter family Multi_Drug_Res PF00893.14 KND99676.1 - 1 9.8 14.5 0.48 10.9 3.2 2.9 3 0 0 3 3 3 0 Small Multidrug Resistance protein Cse1 PF08506.5 KND99677.1 - 2.3e-142 473.9 11.5 2.3e-142 473.9 8.0 1.8 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.10 KND99677.1 - 1.2e-100 336.9 8.5 1.9e-100 336.1 5.9 1.3 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 KND99677.1 - 1e-13 50.9 0.1 1e-12 47.7 0.0 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KND99677.1 - 0.0041 17.0 0.1 0.0041 17.0 0.1 3.7 4 1 0 4 4 4 1 Exportin 1-like protein TetR_C_8 PF14278.1 KND99677.1 - 0.23 11.8 3.9 25 5.3 0.1 4.2 3 1 0 3 3 3 0 Transcriptional regulator C-terminal region CBFB_NFYA PF02045.10 KND99678.1 - 1.2e-29 102.5 7.3 2.4e-29 101.6 5.0 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B FYTT PF07078.6 KND99679.1 - 0.051 12.8 0.0 0.06 12.6 0.0 1.0 1 0 0 1 1 1 0 Forty-two-three protein Vps51 PF08700.6 KND99680.1 - 5.5e-11 42.1 1.6 2.1e-10 40.2 0.1 2.7 2 0 0 2 2 2 1 Vps51/Vps67 PWI PF01480.12 KND99680.1 - 0.36 10.9 5.9 33 4.6 0.0 3.9 3 0 0 3 3 3 0 PWI domain CMS1 PF14617.1 KND99681.1 - 9.2e-23 80.5 15.5 7.4e-12 44.8 3.5 2.5 1 1 2 3 3 3 2 U3-containing 90S pre-ribosomal complex subunit DUF1104 PF06518.6 KND99681.1 - 0.089 12.9 3.4 0.23 11.6 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) GIDA PF01134.17 KND99682.1 - 4.5e-125 417.5 0.0 5.6e-125 417.2 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 KND99682.1 - 2.6e-15 56.2 0.0 6.2e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 GidA associated domain 3 Inhibitor_G39P PF11417.3 KND99682.1 - 0.096 12.6 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Loader and inhibitor of phage G40P CENP-T PF15511.1 KND99683.1 - 3.8e-06 26.4 4.2 5.6e-06 25.8 2.9 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Mito_carr PF00153.22 KND99684.1 - 4.6e-28 96.7 5.1 4.9e-10 38.9 0.1 4.6 4 1 0 4 4 4 4 Mitochondrial carrier protein Acetyltransf_13 PF13880.1 KND99685.1 - 2.6e-19 68.6 0.0 5.4e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 KND99685.1 - 1.6e-09 37.1 0.5 2.5e-09 36.5 0.3 1.3 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 KND99685.1 - 7.7e-05 22.6 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KND99685.1 - 0.0028 17.7 0.0 0.0058 16.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KND99685.1 - 0.0055 16.8 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 KND99685.1 - 0.096 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 QRPTase_C PF01729.14 KND99686.1 - 4.6e-56 188.9 0.0 7.4e-56 188.3 0.0 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 KND99686.1 - 2.7e-27 94.4 0.0 7.4e-27 92.9 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain FMN_dh PF01070.13 KND99686.1 - 0.049 12.4 0.0 0.069 11.9 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase APC10 PF03256.11 KND99687.1 - 4.1e-42 143.9 0.1 2.3e-40 138.2 0.1 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) SMI1_KNR4 PF09346.5 KND99688.1 - 6.6e-35 119.9 0.1 2.6e-34 118.0 0.0 2.0 2 0 0 2 2 2 1 SMI1 / KNR4 family (SUKH-1) GCS PF03074.11 KND99689.1 - 1.2e-131 439.2 0.0 3.5e-108 361.9 0.0 2.3 1 1 1 2 2 2 2 Glutamate-cysteine ligase Leptin PF02024.10 KND99689.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Leptin GCS2 PF04107.8 KND99689.1 - 0.098 11.7 0.0 0.23 10.5 0.0 1.5 2 0 0 2 2 2 0 Glutamate-cysteine ligase family 2(GCS2) GARS_A PF01071.14 KND99691.1 - 5.4e-80 267.5 0.0 1.2e-79 266.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 KND99691.1 - 6.2e-34 116.4 0.5 6.3e-33 113.2 0.0 3.1 4 0 0 4 4 3 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 KND99691.1 - 8.9e-34 116.7 0.1 2e-33 115.5 0.1 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 KND99691.1 - 1.9e-26 92.0 1.0 4.4e-26 90.8 0.7 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 KND99691.1 - 4.2e-17 62.1 4.7 5.3e-17 61.8 1.8 2.4 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 KND99691.1 - 1.5e-09 37.8 0.0 4.6e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KND99691.1 - 2.5e-08 33.0 0.0 5.9e-08 31.8 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KND99691.1 - 2.3e-05 23.8 0.0 5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KND99691.1 - 6e-05 22.9 0.1 0.00042 20.2 0.0 2.4 3 0 0 3 3 3 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KND99691.1 - 0.0024 17.2 0.1 0.0047 16.2 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 KND99691.1 - 0.0069 15.8 1.7 0.026 14.0 0.0 2.6 3 0 0 3 3 3 1 RimK-like ATP-grasp domain Ribonucleas_3_3 PF14622.1 KND99693.1 - 4.3e-05 23.4 0.2 0.00012 22.0 0.1 1.9 1 1 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 KND99693.1 - 0.0016 18.9 0.0 0.0036 17.8 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 KND99693.1 - 0.14 12.6 0.0 0.34 11.3 0.0 1.7 2 0 0 2 2 2 0 Ribonuclease III domain 3-alpha PF03475.9 KND99694.1 - 0.084 12.6 0.2 0.22 11.2 0.2 1.6 2 0 0 2 2 2 0 3-alpha domain EXS PF03124.9 KND99695.1 - 1.6e-58 198.4 23.9 1.9e-58 198.1 16.6 1.0 1 0 0 1 1 1 1 EXS family Nop25 PF09805.4 KND99697.1 - 1.1e-34 119.4 29.4 1.1e-34 119.4 20.4 2.3 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) CytadhesinP1 PF12378.3 KND99697.1 - 0.78 9.7 0.1 0.78 9.7 0.0 2.6 3 1 0 3 3 3 0 Trypsin-sensitive surface-exposed protein Sas10_Utp3 PF04000.10 KND99698.1 - 9e-13 48.2 3.0 2.1e-12 47.0 0.0 2.4 2 1 1 3 3 3 1 Sas10/Utp3/C1D family DUF2802 PF10975.3 KND99698.1 - 0.00027 20.6 0.2 0.00027 20.6 0.1 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF2802) DUF2951 PF11166.3 KND99698.1 - 0.0097 15.7 0.7 0.084 12.7 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2951) Pkinase PF00069.20 KND99699.1 - 2.4e-43 148.1 0.7 3.3e-43 147.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Ribonuc_2-5A PF06479.7 KND99699.1 - 7.8e-43 145.4 0.9 2.1e-42 144.0 0.4 2.0 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 KND99699.1 - 3.9e-22 78.5 0.0 3.1e-21 75.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.1 KND99699.1 - 0.0001 21.8 0.0 0.00088 18.8 0.0 2.4 1 1 0 1 1 1 1 PQQ-like domain Kdo PF06293.9 KND99699.1 - 0.097 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KND99699.1 - 0.17 10.8 0.1 0.37 9.6 0.0 1.5 2 0 0 2 2 2 0 Kinase-like SRP-alpha_N PF04086.8 KND99699.1 - 1.5 8.1 12.8 2.4 7.4 8.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal GRAM PF02893.15 KND99700.1 - 4.4e-20 70.9 0.0 9.4e-20 69.9 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Orthopox_F8 PF05886.6 KND99700.1 - 0.018 14.8 0.6 0.14 11.9 0.3 2.4 2 0 0 2 2 2 0 Orthopoxvirus F8 protein SurE PF01975.12 KND99701.1 - 8.9e-45 152.4 0.0 1.3e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE CCDC66 PF15236.1 KND99702.1 - 0.019 14.6 5.9 0.022 14.3 4.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 HSF_DNA-bind PF00447.12 KND99703.1 - 1.1e-35 121.8 2.1 1.1e-35 121.8 1.4 2.2 2 0 0 2 2 2 1 HSF-type DNA-binding ADIP PF11559.3 KND99703.1 - 7.3 6.4 13.4 0.68 9.8 1.9 3.1 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding BCS1_N PF08740.6 KND99704.1 - 1.4e-48 164.9 0.0 2.4e-48 164.2 0.0 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KND99704.1 - 3.7e-22 78.9 0.0 6e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KND99704.1 - 8e-06 26.6 0.0 1.5e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KND99704.1 - 6.3e-05 23.0 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 KND99704.1 - 0.0012 17.7 0.0 0.002 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.1 KND99704.1 - 0.0021 18.3 0.0 0.0076 16.5 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 KND99704.1 - 0.0036 17.1 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KND99704.1 - 0.0062 16.6 0.0 0.029 14.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KND99704.1 - 0.0076 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 KND99704.1 - 0.0087 15.4 0.0 0.02 14.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KND99704.1 - 0.012 14.6 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KND99704.1 - 0.012 15.4 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KND99704.1 - 0.013 15.2 0.0 0.035 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KND99704.1 - 0.018 14.7 0.0 0.16 11.7 0.0 2.6 3 1 0 3 3 3 0 Part of AAA domain AAA_21 PF13304.1 KND99704.1 - 0.02 14.8 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KND99704.1 - 0.027 14.0 0.0 0.069 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 KND99704.1 - 0.037 14.1 0.0 0.092 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 KND99704.1 - 0.045 14.0 0.0 0.078 13.2 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 KND99704.1 - 0.045 13.4 0.1 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase AAA_28 PF13521.1 KND99704.1 - 0.061 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KND99704.1 - 0.075 12.6 0.7 0.17 11.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 KND99704.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KND99704.1 - 0.16 11.0 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 KaiC UCH PF00443.24 KND99707.1 - 2.1e-48 164.8 8.4 1.3e-47 162.2 5.8 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 KND99707.1 - 4.5e-37 125.2 7.5 7.7e-17 60.4 0.5 5.6 4 1 1 5 5 5 4 A repeated domain in UCH-protein UCH_1 PF13423.1 KND99707.1 - 1.3e-10 41.2 8.5 6.9e-06 25.7 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Mnd1 PF03962.10 KND99707.1 - 0.0008 19.1 2.4 0.002 17.8 1.7 1.6 1 0 0 1 1 1 1 Mnd1 family DUF1664 PF07889.7 KND99707.1 - 0.042 13.6 2.2 0.11 12.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ABC2_membrane PF01061.19 KND99708.1 - 5.8e-37 126.8 11.8 5.8e-37 126.8 8.2 1.8 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.22 KND99708.1 - 7.5e-29 100.7 0.0 2e-28 99.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 KND99708.1 - 1.3e-08 34.2 13.6 1.3e-08 34.2 9.4 1.7 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.1 KND99708.1 - 2.4e-08 34.3 0.1 4.1e-07 30.2 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KND99708.1 - 0.00042 19.7 0.0 0.062 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KND99708.1 - 0.0021 18.0 0.0 0.0042 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KND99708.1 - 0.005 16.5 0.3 0.31 10.7 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.1 KND99708.1 - 0.012 14.6 0.0 2.6 7.0 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.1 KND99708.1 - 0.017 14.6 0.1 0.044 13.3 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 KND99708.1 - 0.019 14.1 0.5 0.045 12.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 KND99708.1 - 0.057 13.3 0.2 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 KND99708.1 - 0.061 12.5 0.0 0.47 9.6 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 KND99708.1 - 0.066 13.1 0.0 0.19 11.6 0.0 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Form-deh_trans PF09163.6 KND99708.1 - 0.45 10.0 3.9 0.14 11.6 0.3 2.0 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane Epimerase PF01370.16 KND99709.1 - 1.8e-14 53.7 0.0 3e-14 53.0 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KND99709.1 - 7e-09 34.7 0.0 9.5e-09 34.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KND99709.1 - 8.4e-06 25.9 0.4 6.3e-05 23.0 0.3 2.3 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KND99709.1 - 0.00046 20.1 0.0 0.00085 19.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KND99709.1 - 0.00052 19.0 0.0 0.013 14.4 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KND99709.1 - 0.0078 15.4 0.3 0.088 12.0 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family Svf1 PF08622.5 KND99711.1 - 3.2e-135 450.2 2.4 3.7e-135 450.0 1.6 1.0 1 0 0 1 1 1 1 Svf1-like CrtC PF07143.6 KND99711.1 - 0.059 12.6 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 Hydroxyneurosporene synthase (CrtC) DUF1151 PF06625.6 KND99715.1 - 2.7 7.7 8.4 0.31 10.7 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) ABC_membrane PF00664.18 KND99717.1 - 0.0036 16.7 2.7 0.012 15.1 0.4 2.4 2 0 0 2 2 2 1 ABC transporter transmembrane region DUF1361 PF07099.6 KND99717.1 - 0.0039 17.0 0.9 0.0039 17.0 0.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1361) Actin PF00022.14 KND99718.1 - 2e-22 79.1 0.0 8.8e-14 50.7 0.0 4.7 3 1 0 3 3 3 2 Actin MreB_Mbl PF06723.8 KND99718.1 - 4.9e-05 22.0 0.3 0.0029 16.2 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein NOA36 PF06524.7 KND99718.1 - 0.28 10.4 13.5 0.079 12.2 6.7 2.0 2 0 0 2 2 2 0 NOA36 protein CDC45 PF02724.9 KND99718.1 - 2.9 5.7 12.6 0.085 10.8 2.0 2.3 2 0 0 2 2 2 0 CDC45-like protein Ligase_CoA PF00549.14 KND99719.1 - 2e-25 89.1 0.0 3.8e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 KND99719.1 - 2.3e-24 85.7 6.2 2.6e-24 85.5 1.9 2.3 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 KND99719.1 - 6.9e-06 25.7 0.0 1.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KND99719.1 - 3e-05 24.1 0.1 9.4e-05 22.5 0.1 1.9 2 0 0 2 2 2 1 CoA binding domain IGR PF09597.5 KND99720.1 - 1.4e-24 85.6 0.7 4.9e-24 83.9 0.4 1.9 2 0 0 2 2 2 1 IGR protein motif LXG PF04740.7 KND99720.1 - 0.027 14.2 0.2 0.027 14.2 0.2 1.5 2 0 0 2 2 2 0 LXG domain of WXG superfamily Pro_isomerase PF00160.16 KND99721.1 - 9.2e-41 139.6 0.1 1.1e-40 139.3 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Med6 PF04934.9 KND99722.1 - 1.1e-54 183.7 0.8 1.6e-54 183.2 0.6 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component HIT PF01230.18 KND99723.1 - 1e-23 83.6 0.0 1.6e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KND99723.1 - 1.2e-06 28.7 0.0 1.7e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KND99723.1 - 0.011 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 SPOB_a PF14689.1 KND99723.1 - 0.015 14.8 0.1 0.031 13.8 0.1 1.5 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain MCR_D PF02505.9 KND99723.1 - 0.17 11.4 0.3 0.37 10.3 0.0 1.6 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein D AhpC-TSA PF00578.16 KND99724.1 - 1.6e-34 118.2 0.0 2.2e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KND99724.1 - 4e-18 65.3 0.0 5.3e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KND99724.1 - 4.3e-13 48.6 0.0 9.8e-13 47.5 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.9 KND99724.1 - 0.022 14.3 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 SCO1/SenC AAA PF00004.24 KND99726.1 - 5.4e-52 175.4 0.7 3.2e-38 130.8 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KND99726.1 - 3.2e-11 43.0 0.0 9.7e-11 41.4 0.0 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_22 PF13401.1 KND99726.1 - 2.5e-10 40.6 1.6 0.00029 21.0 0.2 4.3 2 2 0 2 2 2 2 AAA domain RuvB_N PF05496.7 KND99726.1 - 1.5e-08 34.0 0.1 0.001 18.1 0.0 2.6 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KND99726.1 - 3.2e-08 33.7 0.0 0.011 15.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 KND99726.1 - 8.5e-08 33.0 0.1 0.0021 18.8 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KND99726.1 - 1.2e-07 31.5 0.3 0.002 17.8 0.1 3.1 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KND99726.1 - 3.7e-07 30.2 0.1 6e-05 23.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 KND99726.1 - 1.3e-06 28.7 0.1 0.0082 16.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KND99726.1 - 1.7e-06 27.5 0.0 0.039 13.3 0.0 2.8 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_14 PF13173.1 KND99726.1 - 3.7e-06 26.8 0.3 0.078 12.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KND99726.1 - 5.9e-06 25.9 0.0 0.025 14.3 0.0 2.9 3 0 0 3 3 2 2 Part of AAA domain Sigma54_activat PF00158.21 KND99726.1 - 7.4e-06 25.5 0.1 0.019 14.4 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain TIP49 PF06068.8 KND99726.1 - 9.9e-06 24.5 0.8 0.095 11.3 0.0 2.6 3 0 0 3 3 3 2 TIP49 C-terminus Mg_chelatase PF01078.16 KND99726.1 - 1.1e-05 24.7 0.6 0.007 15.5 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KND99726.1 - 2.4e-05 24.4 0.0 0.13 12.4 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_3 PF07726.6 KND99726.1 - 3.4e-05 23.4 0.0 0.034 13.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KND99726.1 - 0.00011 21.2 0.0 0.28 10.0 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain DUF2075 PF09848.4 KND99726.1 - 0.00017 20.7 0.0 0.029 13.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 KND99726.1 - 0.00018 21.0 0.5 0.42 10.0 0.0 3.4 2 2 1 3 3 3 1 DEAD/DEAH box helicase AAA_24 PF13479.1 KND99726.1 - 0.00021 20.9 0.4 0.13 11.8 0.2 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KND99726.1 - 0.00021 20.7 1.4 0.75 9.1 0.0 3.8 2 2 2 4 4 4 1 AAA domain CDC48_2 PF02933.12 KND99726.1 - 0.00021 20.8 0.3 0.0045 16.6 0.1 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 KaiC PF06745.8 KND99726.1 - 0.00038 19.6 0.9 0.051 12.6 0.0 3.1 2 1 1 3 3 3 1 KaiC ABC_tran PF00005.22 KND99726.1 - 0.00047 20.4 0.1 0.12 12.7 0.1 2.7 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.7 KND99726.1 - 0.00066 19.3 0.1 0.43 10.2 0.0 2.9 2 1 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.7 KND99726.1 - 0.0008 18.5 0.0 0.42 9.6 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 KND99726.1 - 0.0014 18.5 0.0 0.68 9.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain PhoH PF02562.11 KND99726.1 - 0.0029 16.8 0.0 2.4 7.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Torsin PF06309.6 KND99726.1 - 0.0033 17.2 0.0 0.75 9.6 0.0 3.3 3 0 0 3 3 3 1 Torsin Sigma54_activ_2 PF14532.1 KND99726.1 - 0.0035 17.4 0.0 4.2 7.4 0.0 2.9 2 1 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KND99726.1 - 0.0067 15.3 0.0 0.58 8.9 0.0 2.5 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 KND99726.1 - 0.01 15.4 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KND99726.1 - 0.019 14.6 0.0 0.54 9.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 KND99726.1 - 0.078 12.4 0.1 11 5.4 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain KTI12 PF08433.5 KND99726.1 - 0.081 12.1 0.0 2.1 7.4 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 SKI PF01202.17 KND99726.1 - 0.095 12.5 0.3 19 5.0 0.0 2.7 2 1 0 2 2 2 0 Shikimate kinase Aldo_ket_red PF00248.16 KND99729.1 - 1.1e-43 149.1 0.0 1.3e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family MRP-S28 PF10213.4 KND99731.1 - 2e-33 115.1 1.0 3.5e-33 114.3 0.7 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF1086 PF06461.6 KND99731.1 - 0.097 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) Ada3 PF10198.4 KND99733.1 - 5.6e-42 142.5 3.3 5.6e-42 142.5 2.3 2.6 3 1 0 3 3 3 1 Histone acetyltransferases subunit 3 Peptidase_M16 PF00675.15 KND99734.1 - 1.2e-48 164.6 0.1 5.3e-47 159.3 0.0 2.2 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KND99734.1 - 5.9e-33 114.0 0.0 1.1e-32 113.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain RSF PF14876.1 KND99736.1 - 0.076 11.8 0.1 0.08 11.7 0.1 1.0 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator PRELI PF04707.9 KND99737.1 - 1e-47 161.5 0.0 1.3e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family Diphtheria_C PF02763.9 KND99737.1 - 0.0083 15.5 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 Diphtheria toxin, C domain Phosducin PF02114.11 KND99740.1 - 6.4e-09 34.9 0.2 7.8e-09 34.6 0.1 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 KND99740.1 - 2e-06 27.4 0.1 3.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin GnsAB PF08178.6 KND99740.1 - 0.11 12.1 1.2 0.29 10.8 0.4 2.0 2 0 0 2 2 2 0 GnsA/GnsB family Thioredoxin_2 PF13098.1 KND99740.1 - 0.14 12.4 0.3 0.27 11.4 0.2 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain IFRD PF05004.8 KND99740.1 - 0.21 10.6 2.2 1.3 8.0 1.6 2.0 1 1 0 1 1 1 0 Interferon-related developmental regulator (IFRD) HEXIM PF15313.1 KND99740.1 - 0.89 9.7 4.8 2 8.6 3.3 1.6 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein PaaSYMP PF14738.1 KND99740.1 - 2 8.1 5.3 0.67 9.6 1.5 1.8 2 0 0 2 2 2 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 ubiquitin PF00240.18 KND99742.1 - 1.3e-34 117.4 0.9 2.6e-34 116.4 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 KND99742.1 - 2.4e-26 91.2 2.1 4.4e-26 90.4 1.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 KND99742.1 - 5.1e-20 70.9 0.7 9.8e-20 70.0 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KND99742.1 - 8.7e-06 25.9 0.5 3.8e-05 23.8 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KND99742.1 - 0.00012 21.7 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KND99742.1 - 0.0015 18.4 0.3 0.0031 17.3 0.2 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DZR PF12773.2 KND99742.1 - 0.004 16.9 0.5 0.0076 16.0 0.3 1.4 1 0 0 1 1 1 1 Double zinc ribbon DUF2407 PF10302.4 KND99742.1 - 0.007 16.5 0.5 0.0091 16.1 0.3 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain zf-ribbon_3 PF13248.1 KND99742.1 - 0.021 14.0 3.7 0.048 12.8 2.6 1.6 1 1 0 1 1 1 0 zinc-ribbon domain DUF2870 PF11069.3 KND99742.1 - 0.049 13.6 0.2 0.1 12.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 KND99742.1 - 0.12 10.6 2.2 4.7 5.4 0.1 2.2 1 1 0 2 2 2 0 Plexin cytoplasmic RasGAP domain zinc_ribbon_2 PF13240.1 KND99742.1 - 0.13 11.8 3.3 0.44 10.1 0.0 2.7 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KND99742.1 - 0.55 9.8 4.1 14 5.3 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KND99742.1 - 2.4 7.9 5.2 25 4.6 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain Sec10 PF07393.6 KND99743.1 - 1.5e-167 558.9 15.5 2e-167 558.4 10.7 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 THP2 PF09432.5 KND99743.1 - 0.0045 16.8 1.6 0.018 14.8 0.4 2.6 2 0 0 2 2 2 1 Tho complex subunit THP2 Syntaxin PF00804.20 KND99743.1 - 0.022 14.9 0.1 0.022 14.9 0.1 4.0 4 1 0 4 4 4 0 Syntaxin DUF16 PF01519.11 KND99743.1 - 0.032 14.4 4.8 1.2 9.4 1.2 3.6 3 0 0 3 3 3 0 Protein of unknown function DUF16 Vps51 PF08700.6 KND99743.1 - 0.038 13.8 5.4 0.12 12.2 0.7 3.0 2 0 0 2 2 2 0 Vps51/Vps67 Cadherin_pro PF08758.6 KND99743.1 - 0.061 13.1 0.3 17 5.2 0.1 2.5 2 0 0 2 2 2 0 Cadherin prodomain like MtrB PF05440.7 KND99743.1 - 0.074 13.0 0.0 0.25 11.3 0.0 1.9 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B MCPsignal PF00015.16 KND99743.1 - 0.26 10.8 1.6 0.7 9.3 0.3 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF148 PF02520.12 KND99743.1 - 6.4 6.5 13.1 0.65 9.8 0.4 4.0 4 1 1 5 5 5 0 Domain of unknown function DUF148 Metallophos PF00149.23 KND99744.1 - 2.1e-15 56.6 1.6 3.2e-15 56.0 1.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KND99744.1 - 0.00012 21.9 0.1 0.00029 20.7 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SAS4 PF15460.1 KND99745.1 - 1.3e-30 105.2 2.1 1.3e-30 105.2 1.4 2.3 4 0 0 4 4 4 1 Something about silencing, SAS, complex subunit 4 Vfa1 PF08432.5 KND99745.1 - 0.68 9.9 8.5 0.37 10.7 4.4 1.6 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nipped-B_C PF12830.2 KND99746.1 - 5.1e-47 159.9 0.8 5.1e-47 159.9 0.6 4.2 5 1 0 5 5 5 1 Sister chromatid cohesion C-terminus Cnd1 PF12717.2 KND99746.1 - 2.2e-06 27.6 2.3 2.2e-06 27.6 1.6 4.6 5 2 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 KND99746.1 - 0.0024 17.8 3.2 0.0024 17.8 2.2 3.1 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion zf-DHHC PF01529.15 KND99748.1 - 5.9e-33 113.7 10.4 5.9e-33 113.7 7.2 1.6 1 1 1 2 2 2 1 DHHC palmitoyltransferase ATP_synt_I PF03899.10 KND99748.1 - 0.13 12.4 11.2 1.2 9.3 0.7 2.6 2 1 0 2 2 2 0 ATP synthase I chain DUF626 PF04776.7 KND99749.1 - 0.13 12.5 0.4 5 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF626) CybS PF05328.7 KND99750.1 - 1.7e-48 163.5 0.0 2e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 CybS PCI PF01399.22 KND99751.1 - 9.5e-05 22.6 0.3 0.0002 21.6 0.1 1.6 2 0 0 2 2 2 1 PCI domain PXA PF02194.10 KND99752.1 - 1.1e-16 60.8 0.3 2.7e-16 59.6 0.2 1.6 1 0 0 1 1 1 1 PXA domain BPL_LplA_LipB PF03099.14 KND99754.1 - 5.3e-14 52.3 0.2 8.9e-14 51.5 0.1 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DASH_Spc19 PF08287.6 KND99755.1 - 1.2e-32 112.6 12.6 5.4e-32 110.5 8.7 1.8 1 1 0 1 1 1 1 Spc19 DUF1843 PF08898.5 KND99755.1 - 0.021 14.8 0.8 0.068 13.2 0.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) DUF1507 PF07408.6 KND99755.1 - 0.042 13.5 0.1 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1507) Exonuc_VII_L PF02601.10 KND99755.1 - 0.64 9.1 3.6 0.8 8.8 2.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Bcr-Abl_Oligo PF09036.5 KND99755.1 - 0.81 9.6 5.7 0.79 9.7 1.7 2.2 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Atg14 PF10186.4 KND99755.1 - 1.3 7.8 7.8 1.7 7.5 5.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 KND99755.1 - 3 6.8 6.1 3.6 6.5 4.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 FHA PF00498.21 KND99756.1 - 1.6e-09 37.7 0.5 1.2e-07 31.7 0.0 2.7 2 0 0 2 2 2 1 FHA domain Fib_alpha PF08702.5 KND99756.1 - 0.015 15.4 9.0 0.015 15.4 6.3 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DivIC PF04977.10 KND99756.1 - 0.022 14.2 9.9 0.35 10.3 0.2 2.6 2 0 0 2 2 2 0 Septum formation initiator AAA_13 PF13166.1 KND99756.1 - 0.053 11.9 9.2 0.084 11.3 6.4 1.2 1 0 0 1 1 1 0 AAA domain zf-C4H2 PF10146.4 KND99756.1 - 0.054 13.5 5.0 0.077 13.0 3.5 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein DUF4200 PF13863.1 KND99756.1 - 0.084 12.8 12.7 0.058 13.3 4.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Spc7 PF08317.6 KND99756.1 - 0.2 10.2 11.9 0.39 9.3 8.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Spc24 PF08286.6 KND99756.1 - 0.22 11.2 11.2 0.34 10.6 2.6 2.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 XPG_I_2 PF12813.2 KND99756.1 - 0.24 10.8 2.7 0.38 10.1 1.8 1.2 1 0 0 1 1 1 0 XPG domain containing DUF2205 PF10224.4 KND99756.1 - 0.32 10.6 13.0 0.073 12.6 0.6 2.7 1 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF641 PF04859.7 KND99756.1 - 0.73 9.5 7.0 2.6 7.7 4.8 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Viral_P18 PF04521.8 KND99756.1 - 0.99 8.8 6.1 0.34 10.3 0.8 2.4 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein ATG16 PF08614.6 KND99756.1 - 1 9.1 13.4 2.3 7.9 0.6 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) SPX PF03105.14 KND99756.1 - 1.2 8.8 16.4 6.5 6.4 11.4 2.1 1 1 0 1 1 1 0 SPX domain Phage_GP20 PF06810.6 KND99756.1 - 3.6 7.0 11.9 26 4.2 8.3 2.2 1 1 0 1 1 1 0 Phage minor structural protein GP20 DUF16 PF01519.11 KND99756.1 - 4.4 7.5 12.0 4.5 7.5 4.5 2.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 NPV_P10 PF05531.7 KND99756.1 - 5.4 7.3 9.6 4.5 7.5 1.1 2.9 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.6 KND99756.1 - 9.4 6.2 12.7 6.4 6.7 0.4 3.8 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Coq4 PF05019.8 KND99757.1 - 1.9e-102 340.9 0.0 2.3e-102 340.5 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 GyrI-like PF06445.10 KND99757.1 - 0.011 15.7 0.2 0.3 11.1 0.0 2.2 2 0 0 2 2 2 0 GyrI-like small molecule binding domain DUF4112 PF13430.1 KND99759.1 - 2.3e-18 66.0 0.1 2.7e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) IIGP PF05049.8 KND99760.1 - 0.0087 14.9 0.7 0.0097 14.7 0.5 1.0 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) GAT PF03127.9 KND99761.1 - 1e-14 54.2 0.7 3.2e-14 52.7 0.3 2.0 1 1 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 KND99761.1 - 3.9e-14 52.9 0.0 7.6e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Hrs_helical PF12210.3 KND99761.1 - 0.0026 17.9 0.0 0.0062 16.7 0.0 1.6 1 0 0 1 1 1 1 Hepatocyte growth factor-regulated tyrosine kinase substrate Pex19 PF04614.7 KND99761.1 - 0.41 10.2 9.3 0.057 13.0 2.5 2.2 2 1 0 2 2 2 0 Pex19 protein family SLX9 PF15341.1 KND99762.1 - 0.0064 16.9 2.4 0.011 16.2 1.7 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 V_ATPase_I PF01496.14 KND99762.1 - 0.025 12.4 2.8 0.03 12.2 1.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Glyco_transf_92 PF01697.22 KND99762.1 - 0.054 12.7 0.8 0.066 12.5 0.6 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 92 DUF3492 PF11997.3 KND99762.1 - 0.15 11.6 1.4 0.34 10.4 1.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3492) DUF2116 PF09889.4 KND99765.1 - 0.00078 19.1 0.2 0.00096 18.9 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) NapE PF06796.6 KND99765.1 - 0.045 13.0 0.3 0.056 12.7 0.2 1.2 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE AgrB PF04647.10 KND99765.1 - 0.094 11.7 0.5 0.082 11.9 0.4 1.0 1 0 0 1 1 1 0 Accessory gene regulator B Glu_synthase PF01645.12 KND99766.1 - 1.8e-154 514.1 0.0 3.8e-154 513.0 0.0 1.6 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 KND99766.1 - 8.1e-136 452.4 0.0 1.2e-135 451.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 KND99766.1 - 1.6e-118 395.1 0.0 2.8e-118 394.3 0.0 1.4 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 KND99766.1 - 9.1e-67 223.9 2.6 1.6e-66 223.1 1.8 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 KND99766.1 - 1.8e-23 82.2 0.3 4.3e-23 81.0 0.2 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 KND99766.1 - 9.8e-16 58.2 0.0 2.5e-14 53.6 0.0 3.2 4 1 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KND99766.1 - 3.8e-10 40.1 0.1 7e-05 22.9 0.0 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KND99766.1 - 5e-10 39.6 0.0 9.4e-07 29.1 0.0 3.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KND99766.1 - 2.4e-09 37.0 0.0 9.6e-09 35.1 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KND99766.1 - 3.2e-06 26.4 0.0 4.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 KND99766.1 - 4.9e-06 25.7 0.1 5.3e-05 22.4 0.0 2.6 3 0 0 3 3 3 1 Thi4 family DAO PF01266.19 KND99766.1 - 9.6e-06 24.7 0.0 2.2e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KND99766.1 - 6.8e-05 21.5 0.1 6.8e-05 21.5 0.1 1.9 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.19 KND99766.1 - 7.5e-05 21.7 0.0 0.00021 20.2 0.0 1.8 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 KND99766.1 - 9.2e-05 21.6 0.1 0.00018 20.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 KND99766.1 - 0.00028 21.0 0.6 0.13 12.5 0.0 3.0 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.2 KND99766.1 - 0.0028 16.7 0.0 0.0067 15.5 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 KND99766.1 - 0.0073 16.0 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 KND99766.1 - 0.0079 15.3 0.1 0.11 11.6 0.0 2.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KND99766.1 - 0.015 14.9 0.1 0.071 12.6 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 KND99766.1 - 0.016 14.0 0.6 0.074 11.8 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 KND99766.1 - 0.053 13.6 0.1 8.2 6.5 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 KND99766.1 - 0.061 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding DUF46 PF01864.12 KND99766.1 - 0.24 11.2 0.1 0.61 9.9 0.1 1.6 1 0 0 1 1 1 0 Putative integral membrane protein DUF46 RNase_PH PF01138.16 KND99769.1 - 6.1e-16 58.9 0.1 6.5e-14 52.3 0.0 2.7 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KND99769.1 - 0.076 12.9 1.2 0.13 12.2 0.1 2.0 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 StbA PF06406.6 KND99769.1 - 0.078 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 StbA protein UCH PF00443.24 KND99770.1 - 6.5e-80 268.0 0.0 1.4e-79 266.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KND99770.1 - 5.2e-20 72.0 0.4 1.5e-10 40.9 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase CW_binding_1 PF01473.15 KND99770.1 - 0.02 14.9 1.5 0.072 13.2 1.0 1.9 1 0 0 1 1 1 0 Putative cell wall binding repeat MCPVI PF02993.9 KND99770.1 - 0.18 11.9 1.2 0.42 10.7 0.9 1.5 1 0 0 1 1 1 0 Minor capsid protein VI Beach PF02138.13 KND99771.1 - 9.7e-109 362.9 0.2 9.7e-109 362.9 0.1 2.7 3 0 0 3 3 3 1 Beige/BEACH domain PH_BEACH PF14844.1 KND99771.1 - 3.4e-13 49.3 0.0 1e-12 47.8 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 KND99771.1 - 0.0058 16.4 0.0 5.9 6.9 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat TPT PF03151.11 KND99772.1 - 2.1e-20 72.9 9.6 2.1e-20 72.9 6.7 2.4 2 2 0 2 2 2 1 Triose-phosphate Transporter family DUF2012 PF09430.5 KND99773.1 - 0.00028 20.6 0.0 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) MFS_1 PF07690.11 KND99774.1 - 5.9e-32 110.7 56.5 4.2e-23 81.6 23.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND99774.1 - 3.5e-05 22.5 8.3 3.5e-05 22.5 5.8 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter DUF3445 PF11927.3 KND99776.1 - 9.6e-70 234.7 0.4 1.2e-69 234.5 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Ribosomal_S11 PF00411.14 KND99777.1 - 2.6e-41 140.2 0.8 3e-41 140.0 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 DASH_Hsk3 PF08227.6 KND99778.1 - 0.21 11.8 0.9 1.7 8.8 0.0 2.5 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like Peptidase_M1 PF01433.15 KND99782.1 - 1.8e-77 261.0 0.0 2.4e-77 260.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KND99782.1 - 5.4e-42 142.7 0.0 1e-41 141.9 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KND99782.1 - 3.7e-15 56.1 0.0 7.7e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 KND99782.1 - 0.77 9.7 4.9 2.4 8.1 1.6 2.8 2 1 0 2 2 2 0 M61 glycyl aminopeptidase Sel1 PF08238.7 KND99783.1 - 4e-08 33.6 7.2 0.004 17.7 0.0 3.5 3 0 0 3 3 3 3 Sel1 repeat SAC3_GANP PF03399.11 KND99785.1 - 3.4e-41 141.0 1.9 4.8e-41 140.5 1.3 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Peptidase_C12 PF01088.16 KND99786.1 - 1.4e-54 184.5 0.0 1.6e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF1109 PF06532.6 KND99787.1 - 0.0041 16.5 0.4 0.0041 16.5 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1109) Pkinase PF00069.20 KND99788.1 - 1.2e-72 244.1 0.2 1.5e-72 243.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND99788.1 - 1.3e-42 145.6 0.0 1.7e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND99788.1 - 4e-06 25.9 0.0 1.1e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.19 KND99788.1 - 0.00016 22.1 0.8 0.00055 20.4 0.6 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain DUF1374 PF07118.6 KND99788.1 - 0.012 15.6 1.1 0.028 14.4 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1374) APH PF01636.18 KND99788.1 - 0.043 13.5 0.0 6.7 6.3 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family PX PF00787.19 KND99791.1 - 9.4e-09 35.0 0.1 2.6e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 PX domain SH3_9 PF14604.1 KND99791.1 - 7.1e-06 25.5 0.0 1.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KND99791.1 - 0.009 15.3 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain DUF2332 PF10094.4 KND99792.1 - 0.11 11.3 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2332) SH3_1 PF00018.23 KND99793.1 - 3.1e-12 45.6 0.0 8e-12 44.3 0.0 1.8 1 0 0 1 1 1 1 SH3 domain PX PF00787.19 KND99793.1 - 5.4e-10 39.0 0.4 1.5e-09 37.5 0.3 1.7 1 0 0 1 1 1 1 PX domain SH3_9 PF14604.1 KND99793.1 - 1.4e-07 30.9 0.0 2.7e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KND99793.1 - 1.9e-06 27.2 0.0 4.3e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 KND99793.1 - 0.042 14.0 0.1 1.4 9.1 0.0 2.7 2 0 0 2 2 2 0 Bacterial SH3 domain Zn_clus PF00172.13 KND99796.1 - 2.7e-07 30.3 10.6 4.7e-07 29.6 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF221 PF02714.10 KND99798.1 - 2.1e-96 322.6 28.5 3.8e-96 321.7 19.7 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KND99798.1 - 1.9e-35 121.7 5.8 1.9e-35 121.7 4.0 2.6 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KND99798.1 - 0.00025 21.5 0.1 0.00053 20.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) zf-RanBP PF00641.13 KND99800.1 - 1.1e-12 46.7 14.8 2e-09 36.3 0.6 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 KND99800.1 - 2.8e-05 23.6 0.0 0.0001 21.8 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND99800.1 - 0.095 12.6 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 KND99800.1 - 2.8 7.8 10.1 1.8 8.4 0.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon Glycos_transf_2 PF00535.21 KND99801.1 - 2.2e-35 121.8 0.0 2.6e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KND99801.1 - 4.8e-11 42.8 0.0 7.2e-11 42.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KND99801.1 - 1.8e-07 30.5 0.0 2.4e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KND99801.1 - 0.00027 20.2 0.0 0.00044 19.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 ThiF PF00899.16 KND99802.1 - 7.9e-34 116.4 0.0 1.6e-33 115.3 0.0 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 KND99802.1 - 5.4e-26 89.9 1.0 1.1e-25 89.0 0.2 1.9 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KND99802.1 - 4.2e-20 70.8 4.3 7.3e-20 70.0 3.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 KND99802.1 - 0.00099 19.2 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KND99802.1 - 0.099 13.0 0.0 1.3 9.4 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Profilin PF00235.14 KND99803.1 - 4.8e-39 133.2 0.2 5.3e-39 133.0 0.1 1.0 1 0 0 1 1 1 1 Profilin ArfGap PF01412.13 KND99808.1 - 1.3e-28 99.1 0.0 2.8e-28 98.0 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.26 KND99808.1 - 0.0023 17.6 0.0 0.0097 15.7 0.0 2.0 3 0 0 3 3 3 1 UBA/TS-N domain HVSL PF09749.4 KND99809.1 - 0.063 12.2 0.1 0.19 10.7 0.0 1.8 1 1 1 2 2 2 0 Uncharacterised conserved protein Sugar_tr PF00083.19 KND99810.1 - 1e-110 370.4 24.4 1.2e-110 370.1 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND99810.1 - 3e-24 85.3 30.5 3e-24 85.3 21.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily GMC_oxred_N PF00732.14 KND99811.1 - 1.1e-57 195.4 0.2 1.6e-57 194.9 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KND99811.1 - 1.5e-24 86.9 0.3 1.8e-23 83.4 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KND99811.1 - 1.4e-09 37.3 1.1 5.1e-09 35.4 0.7 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KND99811.1 - 7.2e-07 28.4 0.1 0.006 15.5 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KND99811.1 - 0.00049 20.0 0.0 0.0061 16.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KND99811.1 - 0.0043 17.0 0.5 0.011 15.7 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KND99811.1 - 0.0098 14.9 0.1 1 8.3 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 KND99811.1 - 0.029 13.4 0.1 0.06 12.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Mss4 PF04421.8 KND99813.1 - 3.6e-09 36.3 0.7 6.8e-08 32.2 0.5 2.2 1 1 0 1 1 1 1 Mss4 protein APH PF01636.18 KND99814.1 - 5.7e-34 117.8 0.0 7.1e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KND99814.1 - 4.9e-08 32.4 0.0 7.2e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 KND99814.1 - 5e-07 29.5 0.0 8.4e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 KND99814.1 - 0.00086 18.0 0.0 0.0013 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) PKI PF02827.11 KND99815.1 - 0.1 12.7 0.0 0.87 9.7 0.0 2.2 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor LRR_4 PF12799.2 KND99815.1 - 0.14 11.8 8.1 0.18 11.4 1.3 3.4 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KND99815.1 - 1.1 9.7 9.5 19 6.0 0.2 4.9 5 0 0 5 5 5 0 Leucine rich repeat Myticin-prepro PF10690.4 KND99816.1 - 0.027 14.5 0.2 0.03 14.3 0.2 1.1 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel UPF0126 PF03458.8 KND99818.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 UPF0126 domain Aminotran_1_2 PF00155.16 KND99819.1 - 5e-35 121.1 0.0 6.3e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II cNMP_binding PF00027.24 KND99820.1 - 3.6e-29 100.4 0.1 1.3e-13 50.5 0.0 4.2 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 KND99820.1 - 2.2e-21 76.7 0.1 6.5e-21 75.1 0.0 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase DEAD PF00270.24 KND99821.1 - 2.7e-05 23.7 0.0 0.0001 21.8 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase PIF1 PF05970.9 KND99822.1 - 2e-64 217.8 0.1 2.6e-50 171.4 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 KND99822.1 - 2.2e-14 53.4 0.0 2.5e-13 50.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KND99822.1 - 8.2e-08 32.4 0.1 2.1e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KND99822.1 - 2.8e-07 29.8 0.2 0.0082 15.1 0.0 3.1 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) Herpes_Helicase PF02689.9 KND99822.1 - 1.7e-05 22.8 0.1 0.00021 19.2 0.0 2.0 2 0 0 2 2 2 1 Helicase AAA_19 PF13245.1 KND99822.1 - 2.1e-05 24.1 0.0 5.2e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 KND99822.1 - 4.3e-05 23.7 0.0 9.6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.1 KND99822.1 - 0.00015 21.8 0.0 0.0068 16.5 0.0 2.7 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.9 KND99822.1 - 0.0016 18.0 0.2 0.0057 16.3 0.1 1.9 1 1 0 1 1 1 1 Helicase NACHT PF05729.7 KND99822.1 - 0.0032 17.1 0.0 0.0077 15.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 KND99822.1 - 0.0043 16.9 0.3 0.055 13.3 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KND99822.1 - 0.0084 15.6 0.2 2.9 7.3 0.0 3.1 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KND99822.1 - 0.0091 15.9 0.6 0.035 14.1 0.1 2.0 1 1 0 2 2 2 1 AAA ATPase domain DEAD PF00270.24 KND99822.1 - 0.01 15.3 0.6 4.4 6.7 0.0 2.5 1 1 0 2 2 2 0 DEAD/DEAH box helicase PhoH PF02562.11 KND99822.1 - 0.012 14.8 0.0 0.023 13.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NTPase_1 PF03266.10 KND99822.1 - 0.015 14.9 0.3 0.073 12.7 0.1 2.0 2 0 0 2 2 2 0 NTPase Viral_helicase1 PF01443.13 KND99822.1 - 0.017 14.6 0.8 0.65 9.4 0.2 2.8 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 KND99822.1 - 0.022 14.1 0.1 0.19 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KND99822.1 - 0.023 14.9 0.6 0.092 13.0 0.2 2.0 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 KND99822.1 - 0.031 14.4 0.1 0.096 12.8 0.1 1.8 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 KND99822.1 - 0.05 12.7 0.1 0.093 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 KND99822.1 - 0.051 13.0 0.2 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.9 KND99822.1 - 0.15 11.7 0.2 0.34 10.6 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 KND99822.1 - 0.26 10.1 1.7 0.69 8.7 1.2 1.7 1 1 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 KND99822.1 - 0.51 10.0 6.1 0.099 12.3 0.7 2.3 2 1 0 2 2 1 0 Archaeal ATPase Sec39 PF08314.6 KND99823.1 - 8.5e-51 172.7 8.8 1.4e-50 172.0 6.1 1.3 1 1 0 1 1 1 1 Secretory pathway protein Sec39 Bacillus_HBL PF05791.6 KND99824.1 - 0.0034 16.7 1.0 0.0089 15.4 0.7 1.7 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) bZIP_1 PF00170.16 KND99824.1 - 0.0075 16.2 0.2 0.0075 16.2 0.1 3.1 4 0 0 4 4 4 1 bZIP transcription factor STAT_alpha PF01017.15 KND99824.1 - 0.045 13.4 5.5 0.049 13.3 1.9 2.3 2 1 0 2 2 2 0 STAT protein, all-alpha domain DASH_Dam1 PF08653.5 KND99824.1 - 0.063 13.0 1.1 25 4.7 0.0 3.7 3 1 0 3 3 3 0 DASH complex subunit Dam1 Mit_KHE1 PF10173.4 KND99824.1 - 0.068 13.0 2.1 0.11 12.2 1.4 1.3 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DivIC PF04977.10 KND99824.1 - 0.17 11.3 9.1 0.083 12.3 0.4 3.2 3 1 0 3 3 3 0 Septum formation initiator DUF904 PF06005.7 KND99824.1 - 0.21 11.9 0.2 0.21 11.9 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF904) Fib_alpha PF08702.5 KND99824.1 - 1.8 8.6 5.3 0.72 9.9 0.9 2.4 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF342 PF03961.8 KND99824.1 - 2.5 6.4 6.3 1.1 7.6 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DivIVA PF05103.8 KND99824.1 - 4.1 7.4 11.1 5.3 7.0 2.9 3.4 3 1 0 3 3 3 0 DivIVA protein LSM PF01423.17 KND99825.1 - 1.4e-18 66.1 0.1 1.8e-18 65.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF2272 PF10030.4 KND99825.1 - 0.14 11.6 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2272) NAD_binding_6 PF08030.7 KND99826.1 - 9.9e-22 77.5 0.0 1.6e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KND99826.1 - 1.2e-21 76.5 0.0 2.2e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KND99826.1 - 4.5e-19 68.7 13.2 4.5e-19 68.7 9.2 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component adh_short PF00106.20 KND99830.1 - 4e-22 78.8 0.0 5.2e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KND99830.1 - 5.3e-15 55.8 0.0 6.9e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KND99830.1 - 6.1e-11 42.3 0.0 8.7e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KND99830.1 - 0.0022 17.4 0.0 0.0039 16.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KND99830.1 - 0.0057 16.6 0.0 0.043 13.8 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding ApbA PF02558.11 KND99830.1 - 0.0059 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA THF_DHG_CYH_C PF02882.14 KND99830.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 KND99830.1 - 0.014 15.1 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3104 PF11302.3 KND99830.1 - 0.061 12.7 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Ribosomal_L17 PF01196.14 KND99831.1 - 2.4e-21 76.1 0.5 3.8e-21 75.4 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L17 TMA7 PF09072.5 KND99832.1 - 1.1e-27 96.2 20.5 1.3e-27 96.0 14.2 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 LAP2alpha PF11560.3 KND99832.1 - 0.067 12.3 0.3 0.073 12.2 0.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 2 alpha cobW PF02492.14 KND99833.1 - 3e-48 163.6 9.1 4e-47 159.9 4.6 2.5 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KND99833.1 - 2.1e-19 69.0 0.0 6.2e-16 57.8 0.0 2.5 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.22 KND99833.1 - 0.0015 18.0 1.3 0.57 9.5 0.1 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 KND99833.1 - 0.0026 16.5 0.2 1.1 7.9 0.0 2.5 2 1 0 2 2 2 2 ArgK protein CDC45 PF02724.9 KND99833.1 - 0.0038 15.3 5.0 0.0056 14.7 3.5 1.2 1 0 0 1 1 1 1 CDC45-like protein MobB PF03205.9 KND99833.1 - 0.0064 16.2 0.2 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Nop14 PF04147.7 KND99833.1 - 0.0092 13.9 11.5 0.016 13.1 8.0 1.3 1 0 0 1 1 1 1 Nop14-like family ATP_bind_1 PF03029.12 KND99833.1 - 0.023 14.2 0.1 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF4637 PF15470.1 KND99833.1 - 0.027 14.0 0.3 0.048 13.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) AAA_22 PF13401.1 KND99833.1 - 0.035 14.2 0.2 0.27 11.3 0.0 2.3 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.1 KND99833.1 - 0.053 13.8 0.0 0.053 13.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 KND99833.1 - 0.053 13.3 0.0 0.098 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KND99833.1 - 0.059 12.2 0.1 0.09 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 KND99833.1 - 0.064 12.7 0.1 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KND99833.1 - 0.081 12.9 3.4 0.13 12.2 0.0 2.7 4 0 0 4 4 2 0 AAA ATPase domain CobT PF06213.7 KND99833.1 - 0.14 11.2 10.0 0.27 10.3 6.9 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RNA_pol_3_Rpc31 PF11705.3 KND99833.1 - 0.15 11.9 16.7 0.18 11.7 10.4 2.0 2 0 0 2 2 1 0 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.5 KND99833.1 - 0.25 10.3 10.1 0.45 9.5 7.0 1.3 1 0 0 1 1 1 0 BUD22 AAA_14 PF13173.1 KND99833.1 - 0.27 11.1 0.1 0.27 11.1 0.0 2.6 2 1 0 3 3 2 0 AAA domain RRN3 PF05327.6 KND99833.1 - 0.64 8.0 4.3 1.2 7.2 3.0 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2457 PF10446.4 KND99833.1 - 7.6 5.1 22.9 12 4.4 15.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) WH1 PF00568.18 KND99837.1 - 1.5e-30 105.2 0.0 2.8e-30 104.2 0.0 1.4 2 0 0 2 2 2 1 WH1 domain WH2 PF02205.15 KND99837.1 - 4.4e-06 26.1 0.7 1.1e-05 24.8 0.5 1.8 1 0 0 1 1 1 1 WH2 motif Esterase PF00756.15 KND99839.1 - 1.2e-54 185.4 0.0 1.5e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KND99839.1 - 3.7e-11 42.9 0.0 4.9e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KND99839.1 - 2.5e-07 30.1 0.2 4.7e-07 29.2 0.1 1.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KND99839.1 - 1.1e-06 28.7 0.0 3.4e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND99839.1 - 5.2e-05 22.9 0.0 8e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 KND99839.1 - 0.00034 19.6 0.0 0.00068 18.5 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KND99839.1 - 0.001 17.9 0.1 0.51 9.0 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase Abhydrolase_2 PF02230.11 KND99839.1 - 0.0031 16.9 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase AXE1 PF05448.7 KND99839.1 - 0.0044 15.5 0.0 0.0066 14.9 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.20 KND99839.1 - 0.045 13.3 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Esterase_phd PF10503.4 KND99839.1 - 0.058 12.6 0.0 0.44 9.7 0.0 2.1 2 1 0 2 2 2 0 Esterase PHB depolymerase DUF915 PF06028.6 KND99839.1 - 0.076 12.0 0.1 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) MFS_1 PF07690.11 KND99840.1 - 4.3e-30 104.6 43.7 1.1e-25 90.1 14.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KND99840.1 - 1.9e-22 79.5 21.3 8.5e-22 77.3 14.8 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4064 PF13273.1 KND99840.1 - 5.6 7.1 9.3 5.3 7.2 0.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) SNARE_assoc PF09335.6 KND99842.1 - 1.4e-15 57.6 2.8 1.4e-15 57.6 1.9 2.2 2 0 0 2 2 2 1 SNARE associated Golgi protein LRR19-TM PF15176.1 KND99842.1 - 0.17 11.6 0.7 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain LIM PF00412.17 KND99843.1 - 4.1e-12 45.9 21.3 9.5e-08 31.9 4.9 2.6 2 0 0 2 2 2 2 LIM domain HTH_32 PF13565.1 KND99844.1 - 0.013 16.2 0.2 0.017 15.8 0.1 1.2 1 0 0 1 1 1 0 Homeodomain-like domain DUF550 PF04447.7 KND99844.1 - 0.098 12.2 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF550) Ribosomal_S11 PF00411.14 KND99846.1 - 0.0012 18.9 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S11 BRX_N PF13713.1 KND99847.1 - 0.12 11.8 0.4 4.6 6.7 0.0 2.0 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain Pkinase PF00069.20 KND99848.1 - 1.5e-57 194.6 0.0 1.9e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND99848.1 - 7.2e-28 97.3 0.0 1.1e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND99848.1 - 0.00054 19.0 0.0 0.00087 18.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KND99848.1 - 0.00068 18.7 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KND99848.1 - 0.014 14.2 0.3 0.024 13.4 0.2 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 KND99848.1 - 0.032 13.9 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Intg_mem_TP0381 PF09529.5 KND99849.1 - 0.11 11.7 1.3 0.12 11.6 0.9 1.0 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) UPF0220 PF05255.6 KND99850.1 - 5.8e-72 240.3 4.4 6.5e-72 240.1 3.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF360 PF04020.8 KND99850.1 - 0.013 15.7 4.8 0.64 10.3 0.3 2.2 2 0 0 2 2 2 0 Membrane protein of unknown function DUF3169 PF11368.3 KND99850.1 - 0.095 11.8 5.1 0.18 10.9 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Jiraiya PF15038.1 KND99850.1 - 0.37 10.1 6.7 0.059 12.7 1.1 1.8 1 1 1 2 2 2 0 Jiraiya WD40 PF00400.27 KND99851.1 - 8.5e-38 126.9 17.0 3.6e-08 32.9 0.1 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KND99851.1 - 3.1e-07 29.5 3.6 0.0018 17.1 0.2 3.4 1 1 2 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 KND99851.1 - 2.6e-06 25.8 6.1 0.15 10.1 0.1 3.4 1 1 2 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.6 KND99851.1 - 1.5e-05 24.7 0.2 0.12 12.0 0.1 3.6 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 KND99851.1 - 3.2e-05 23.5 0.7 0.00061 19.3 0.1 2.5 2 1 0 2 2 2 1 PQQ-like domain DUF3312 PF11768.3 KND99851.1 - 0.0085 14.3 0.1 0.016 13.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3312) Herpes_gE PF02480.11 KND99851.1 - 0.026 12.8 0.0 0.04 12.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Utp8 PF10395.4 KND99851.1 - 0.045 12.0 0.7 0.19 9.9 0.0 2.0 2 1 0 2 2 2 0 Utp8 family Herpes_gI PF01688.12 KND99851.1 - 0.047 12.8 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I USP7_C2 PF14533.1 KND99851.1 - 0.091 12.1 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal Helitron_like_N PF14214.1 KND99851.1 - 0.091 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus Pkinase PF00069.20 KND99852.1 - 2.8e-66 223.3 0.0 9.9e-66 221.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND99852.1 - 1.4e-42 145.6 0.0 2.1e-42 144.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND99852.1 - 7.6e-06 25.0 0.0 3.5e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KND99852.1 - 0.011 14.8 0.5 0.044 12.8 0.0 2.2 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KND99852.1 - 0.021 14.5 0.0 5.4 6.6 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Glycos_transf_4 PF00953.16 KND99853.1 - 0.023 14.4 0.8 0.036 13.8 0.6 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 4 CorA PF01544.13 KND99853.1 - 0.26 10.2 11.6 3.6 6.5 8.0 2.2 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein FCH PF00611.18 KND99854.1 - 0.0045 17.1 0.4 0.076 13.2 0.2 2.8 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 KND99854.1 - 0.036 13.6 0.1 0.036 13.6 0.0 2.6 2 1 0 2 2 2 0 RhoGAP domain PPR_2 PF13041.1 KND99855.1 - 0.022 14.7 2.4 0.27 11.2 0.1 3.3 4 0 0 4 4 4 0 PPR repeat family eIF3_subunit PF08597.5 KND99856.1 - 2.3e-67 227.1 26.3 2.6e-67 226.9 18.3 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Ycf1 PF05758.7 KND99856.1 - 1.4 6.4 5.6 1.5 6.4 3.9 1.2 1 0 0 1 1 1 0 Ycf1 TEX19 PF15553.1 KND99856.1 - 1.7 8.4 8.1 3.7 7.4 5.6 1.6 1 0 0 1 1 1 0 Testis-expressed protein 19 Peptidase_C58 PF03543.9 KND99856.1 - 3.3 7.1 8.2 0.5 9.8 2.6 1.8 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen DUF572 PF04502.8 KND99856.1 - 3.5 6.7 15.8 0.33 10.1 7.5 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF572) SET PF00856.23 KND99857.1 - 1.6e-10 41.5 0.0 9.2e-10 39.0 0.0 2.2 1 1 0 1 1 1 1 SET domain Thioredoxin PF00085.15 KND99858.1 - 8.6e-33 112.1 0.2 9.5e-33 111.9 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KND99858.1 - 9.5e-09 35.4 0.3 1.3e-07 31.7 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KND99858.1 - 5.2e-08 32.9 0.1 2.5e-06 27.4 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KND99858.1 - 8e-07 28.6 0.0 8.5e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 KND99858.1 - 2.6e-05 23.8 0.3 0.0015 18.0 0.1 2.1 1 1 1 2 2 2 1 Redoxin Phosducin PF02114.11 KND99858.1 - 0.00015 20.5 0.0 0.00015 20.5 0.0 1.0 1 0 0 1 1 1 1 Phosducin Glutaredoxin PF00462.19 KND99858.1 - 0.00021 21.1 0.4 0.00064 19.6 0.1 1.8 1 1 1 2 2 2 1 Glutaredoxin DIM1 PF02966.11 KND99858.1 - 0.00028 20.3 0.0 0.00028 20.3 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 AhpC-TSA PF00578.16 KND99858.1 - 0.00051 19.7 0.2 0.028 14.1 0.1 2.0 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.1 KND99858.1 - 0.0014 18.6 0.1 0.0044 16.9 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.1 KND99858.1 - 0.0051 16.6 0.1 0.0075 16.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain HyaE PF07449.6 KND99858.1 - 0.013 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE TraF PF13728.1 KND99858.1 - 0.015 14.7 0.0 0.021 14.3 0.0 1.3 1 1 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_5 PF13743.1 KND99858.1 - 0.056 13.0 0.3 0.16 11.4 0.1 1.8 1 1 1 2 2 2 0 Thioredoxin DUF2874 PF11396.3 KND99858.1 - 0.09 12.7 1.2 0.27 11.2 0.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2874) Y_phosphatase PF00102.22 KND99859.1 - 3.5e-52 177.0 0.0 5.6e-52 176.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 KND99859.1 - 1.6e-07 31.6 0.0 5.3e-07 29.9 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 KND99859.1 - 0.011 16.0 0.5 0.028 14.6 0.2 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family TRAPP PF04051.11 KND99864.1 - 3.5e-42 143.4 0.0 4.3e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Acetyltransf_1 PF00583.19 KND99865.1 - 5.5e-15 55.1 0.0 7.8e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KND99865.1 - 1.2e-05 24.9 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KND99865.1 - 2.3e-05 24.4 0.0 3.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KND99865.1 - 3.6e-05 23.8 0.0 5.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KND99865.1 - 0.0013 18.9 0.1 0.0051 16.9 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KND99865.1 - 0.0014 18.4 1.1 0.0021 17.9 0.2 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain KH_1 PF00013.24 KND99866.1 - 0.00025 20.6 0.4 0.00057 19.4 0.3 1.6 1 0 0 1 1 1 1 KH domain MDM31_MDM32 PF08118.6 KND99868.1 - 3.3e-52 177.6 17.2 7e-31 107.2 3.4 4.2 3 2 1 4 4 4 4 Yeast mitochondrial distribution and morphology (MDM) proteins DUF568 PF04526.8 KND99868.1 - 0.033 14.4 0.0 2.9 8.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF568) G-patch_2 PF12656.2 KND99869.1 - 5.4e-17 61.4 0.2 1.6e-16 59.9 0.1 1.9 2 0 0 2 2 2 1 DExH-box splicing factor binding site SE PF08491.5 KND99869.1 - 0.1 11.4 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Squalene epoxidase AAA PF00004.24 KND99871.1 - 0.00033 20.8 0.0 0.00096 19.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KND99871.1 - 0.035 14.0 0.0 1 9.2 0.0 3.3 3 1 0 3 3 3 0 AAA domain AAA_5 PF07728.9 KND99871.1 - 0.075 12.7 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TFIID-18kDa PF02269.11 KND99872.1 - 3.1e-32 110.2 3.3 4.3e-32 109.7 0.1 2.6 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit Syntaxin-6_N PF09177.6 KND99873.1 - 6.1e-16 58.6 0.9 6.1e-16 58.6 0.6 2.6 3 0 0 3 3 3 1 Syntaxin 6, N-terminal SNARE PF05739.14 KND99873.1 - 5e-13 48.5 6.5 5e-13 48.5 4.5 2.2 2 0 0 2 2 2 1 SNARE domain Sas10_Utp3 PF04000.10 KND99873.1 - 0.0073 16.4 1.0 3.6 7.8 0.5 2.7 3 0 0 3 3 3 2 Sas10/Utp3/C1D family Laminin_II PF06009.7 KND99873.1 - 0.011 15.5 4.0 0.047 13.4 0.2 2.2 2 0 0 2 2 2 0 Laminin Domain II DUF4391 PF14335.1 KND99873.1 - 0.11 11.8 5.8 0.016 14.5 1.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) DUF1664 PF07889.7 KND99873.1 - 0.84 9.4 6.4 0.48 10.2 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF1732 PF08340.6 KND99873.1 - 2.2 8.1 7.1 0.36 10.6 1.2 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1732) Dpy-30 PF05186.8 KND99874.1 - 1.3e-12 47.0 0.0 7.5e-12 44.5 0.0 2.0 2 0 0 2 2 2 1 Dpy-30 motif Mito_carr PF00153.22 KND99875.1 - 7.5e-10 38.3 0.2 0.0023 17.6 0.0 3.8 4 0 0 4 4 4 3 Mitochondrial carrier protein Vps5 PF09325.5 KND99876.1 - 9.6e-07 28.2 12.1 2.1e-06 27.1 8.4 1.5 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KND99876.1 - 0.0013 18.5 0.1 0.0013 18.5 0.0 2.3 3 0 0 3 3 3 1 PX domain Prok-TraM PF09228.5 KND99876.1 - 0.0078 16.3 0.9 0.031 14.4 0.5 2.2 1 1 0 1 1 1 1 Prokaryotic Transcriptional repressor TraM Sod_Fe_C PF02777.13 KND99877.1 - 1.3e-35 121.3 0.3 2.5e-35 120.5 0.2 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KND99877.1 - 1e-28 99.4 0.8 2.1e-28 98.4 0.5 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Snf7 PF03357.16 KND99878.1 - 3.2e-16 59.2 17.8 4.6e-16 58.6 12.4 1.3 1 1 0 1 1 1 1 Snf7 Cytochrom_B562 PF07361.6 KND99878.1 - 0.026 14.9 1.8 0.026 14.9 1.3 2.4 2 1 0 2 2 2 0 Cytochrome b562 Prominin PF05478.6 KND99878.1 - 0.11 9.9 7.2 0.13 9.7 5.0 1.2 1 0 0 1 1 1 0 Prominin Troponin PF00992.15 KND99878.1 - 0.24 11.4 7.7 3.6 7.6 0.2 2.4 2 0 0 2 2 2 0 Troponin GvpK PF05121.7 KND99878.1 - 0.3 10.9 7.4 1.7 8.5 0.1 3.7 3 1 1 4 4 4 0 Gas vesicle protein K DUF883 PF05957.8 KND99878.1 - 8.6 6.8 8.8 26 5.3 3.8 2.9 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) TPR_11 PF13414.1 KND99879.1 - 1.5e-12 46.9 4.0 5.6e-11 41.9 0.2 2.7 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KND99879.1 - 8.3e-07 28.3 2.3 0.008 15.7 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KND99879.1 - 4.6e-06 26.1 1.1 0.48 10.4 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KND99879.1 - 0.0026 17.6 3.4 0.091 12.7 2.4 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KND99879.1 - 0.015 15.1 0.0 0.04 13.7 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat BTAD PF03704.12 KND99879.1 - 0.077 13.2 0.1 0.26 11.5 0.1 1.9 1 0 0 1 1 1 0 Bacterial transcriptional activator domain Cid2 PF09774.4 KND99880.1 - 6.5e-32 110.7 3.7 9.2e-32 110.2 2.6 1.2 1 0 0 1 1 1 1 Caffeine-induced death protein 2 DDE_Tnp_1_assoc PF13808.1 KND99880.1 - 0.042 13.5 0.1 0.16 11.6 0.0 2.0 3 0 0 3 3 3 0 DDE_Tnp_1-associated Pkinase PF00069.20 KND99881.1 - 7.1e-62 208.8 0.0 1.5e-61 207.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KND99881.1 - 3.9e-30 104.7 0.0 8.1e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KND99881.1 - 2.5e-05 23.3 0.0 0.00012 21.1 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Peptidase_M3 PF01432.15 KND99882.1 - 1.3e-109 367.2 1.4 1.7e-109 366.8 1.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 RPW8 PF05659.6 KND99882.1 - 0.02 14.4 0.1 0.039 13.4 0.1 1.5 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Peptidase_M50B PF13398.1 KND99882.1 - 0.084 12.2 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Ycf34 PF10718.4 KND99883.1 - 0.045 14.1 0.4 0.061 13.7 0.3 1.3 1 0 0 1 1 1 0 Hypothetical chloroplast protein Ycf34 tRNA-synt_2b PF00587.20 KND99884.1 - 1.8e-31 109.0 0.0 2.7e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KND99884.1 - 8.8e-07 28.9 1.6 9.5e-07 28.8 0.4 1.6 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Osmo_MPGsynth PF09488.5 KND99885.1 - 0.007 15.0 0.5 0.091 11.4 0.1 2.2 2 1 0 2 2 2 1 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) DUF2737 PF10930.3 KND99885.1 - 0.91 9.1 4.6 2.8 7.6 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2737) DUF2508 PF10704.4 KND99886.1 - 0.17 12.0 3.9 0.17 12.1 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) Lgl_C PF08596.5 KND99887.1 - 3.9e-104 348.2 0.0 6.3e-103 344.2 0.0 2.1 2 0 0 2 2 2 2 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 KND99887.1 - 0.0022 17.7 0.1 2.8 7.9 0.0 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat DPM2 PF07297.7 KND99889.1 - 1.4e-27 95.7 1.1 1.6e-27 95.6 0.7 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 KND99889.1 - 0.0028 17.2 0.4 0.0029 17.2 0.3 1.1 1 0 0 1 1 1 1 PIG-P O-ag_pol_Wzy PF14296.1 KND99889.1 - 0.0039 15.8 0.1 0.0043 15.6 0.1 1.0 1 0 0 1 1 1 1 O-antigen polysaccharide polymerase Wzy Colicin_V PF02674.11 KND99889.1 - 0.043 13.6 0.5 0.048 13.5 0.4 1.2 1 1 0 1 1 1 0 Colicin V production protein EpuA PF11772.3 KND99889.1 - 0.47 9.9 2.7 0.9 9.0 1.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Adap_comp_sub PF00928.16 KND99890.1 - 3.9e-38 131.0 0.0 3.7e-31 108.1 0.0 2.1 2 0 0 2 2 2 2 Adaptor complexes medium subunit family Cu-oxidase_2 PF07731.9 KND99891.1 - 3.6e-45 152.8 4.5 8.8e-41 138.6 0.2 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KND99891.1 - 4.1e-45 152.3 3.0 7.8e-41 138.5 0.2 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KND99891.1 - 3.1e-35 121.4 2.6 3.4e-28 98.5 0.1 3.3 3 0 0 3 3 3 3 Multicopper oxidase C1q PF00386.16 KND99891.1 - 0.0084 16.1 0.1 0.14 12.1 0.0 2.6 2 0 0 2 2 2 1 C1q domain Cupredoxin_1 PF13473.1 KND99891.1 - 0.011 15.6 0.0 0.61 9.9 0.0 3.2 2 1 0 2 2 2 0 Cupredoxin-like domain KH_dom-like PF14714.1 KND99892.1 - 0.059 13.3 0.0 0.059 13.3 0.0 1.1 1 0 0 1 1 1 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Abhydrolase_6 PF12697.2 KND99894.1 - 2.7e-18 66.6 0.0 3.7e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KND99894.1 - 0.00014 21.4 0.0 0.025 14.1 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 KND99894.1 - 0.047 13.2 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase ThiF PF00899.16 KND99896.1 - 5.3e-36 123.4 0.3 1.1e-35 122.4 0.2 1.5 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.5 KND99896.1 - 1.1e-22 79.6 0.0 2.2e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 KND99896.1 - 4.3e-21 74.2 1.0 9.3e-21 73.1 0.7 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KND99896.1 - 6.8e-17 60.5 1.8 1.4e-16 59.6 1.2 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 KND99896.1 - 1.2e-05 25.4 0.0 4.1e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KND99896.1 - 0.041 14.1 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding DNA_ligase_ZBD PF03119.11 KND99896.1 - 0.061 13.0 0.2 0.17 11.5 0.1 1.8 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Pyr_redox PF00070.22 KND99896.1 - 0.15 12.4 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Rad52_Rad22 PF04098.10 KND99897.1 - 9.2e-58 194.3 0.0 1.8e-57 193.4 0.0 1.4 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein DUF2195 PF09961.4 KND99898.1 - 0.064 13.0 0.1 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2195) DDE_Tnp_1 PF01609.16 KND99898.1 - 0.14 11.7 3.0 0.16 11.4 2.1 1.2 1 0 0 1 1 1 0 Transposase DDE domain LSM PF01423.17 KND99899.1 - 5.1e-14 51.5 0.1 6.2e-14 51.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain HECT PF00632.20 KND99900.1 - 2.1e-95 319.5 0.0 7e-95 317.8 0.0 2.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 KND99900.1 - 7.9e-69 232.4 3.4 7.9e-69 232.4 2.3 3.4 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF913 PF06025.7 KND99900.1 - 3.2e-38 131.4 0.0 3.2e-38 131.4 0.0 1.8 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) DUF4414 PF14377.1 KND99900.1 - 8e-18 64.3 0.6 8e-18 64.3 0.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4414) Phage_Gp23 PF10669.4 KND99900.1 - 0.00078 19.5 7.3 0.0027 17.8 5.0 1.9 1 0 0 1 1 1 1 Protein gp23 (Bacteriophage A118) 4HBT_2 PF13279.1 KND99901.1 - 1.5e-09 38.2 0.0 2.2e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily ELO PF01151.13 KND99905.1 - 2.2e-60 204.0 24.3 2.9e-60 203.6 16.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family P22_AR_C PF10548.4 KND99906.1 - 0.096 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 P22AR C-terminal domain CNH PF00780.17 KND99907.1 - 4.4e-72 242.7 0.0 1.1e-71 241.4 0.0 1.6 2 0 0 2 2 2 1 CNH domain RhoGEF PF00621.15 KND99907.1 - 5.3e-41 140.4 0.3 1.1e-40 139.4 0.2 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 KND99907.1 - 1.1e-23 83.6 0.3 2.3e-23 82.6 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.16 KND99907.1 - 1.1e-12 47.4 0.0 2.4e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Ribonuc_2-5A PF06479.7 KND99907.1 - 0.0094 15.8 0.2 3.6 7.4 0.2 2.6 2 0 0 2 2 2 2 Ribonuclease 2-5A NuA4 PF09340.5 KND99908.1 - 0.0082 15.7 0.0 0.01 15.4 0.0 1.1 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 P21-Arc PF04062.9 KND99910.1 - 7.7e-81 270.0 0.0 8.6e-81 269.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Metallophos PF00149.23 KND99911.1 - 4.5e-08 32.7 6.1 5.3e-08 32.5 2.8 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase RRM_1 PF00076.17 KND99912.1 - 9.5e-15 54.0 0.0 1.4e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KND99912.1 - 4.1e-13 49.1 0.0 6.4e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KND99912.1 - 6.3e-09 35.5 0.0 1.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 KND99913.1 - 4.8e-16 58.6 0.1 9.3e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain FAD_binding_2 PF00890.19 KND99915.1 - 3e-123 411.7 2.7 3.7e-123 411.4 1.9 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 KND99915.1 - 5e-48 162.2 0.6 7.5e-48 161.6 0.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.12 KND99915.1 - 1.1e-06 27.9 0.3 0.0008 18.5 0.0 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 KND99915.1 - 2.4e-06 26.6 0.4 0.00099 18.0 0.5 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KND99915.1 - 6.5e-06 26.1 2.5 0.00017 21.5 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KND99915.1 - 2.9e-05 23.1 0.5 0.00038 19.4 0.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KND99915.1 - 0.0042 16.1 0.1 0.0083 15.2 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KND99915.1 - 0.015 13.7 0.0 0.082 11.3 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 KND99915.1 - 0.025 14.6 2.3 1.6 8.7 0.4 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ATP-synt_D PF01813.12 KND99916.1 - 2.9e-66 222.7 5.3 3.6e-66 222.4 3.7 1.1 1 0 0 1 1 1 1 ATP synthase subunit D DUF1664 PF07889.7 KND99916.1 - 0.47 10.2 5.3 0.49 10.1 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Ribosomal_L6e PF01159.14 KND99916.1 - 3.1 8.0 6.4 0.48 10.6 0.9 2.1 2 1 0 2 2 2 0 Ribosomal protein L6e Trm112p PF03966.11 KND99917.1 - 2.7e-17 62.8 0.1 3.5e-17 62.5 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein ADK_lid PF05191.9 KND99917.1 - 0.01 15.4 1.1 0.023 14.3 0.8 1.6 1 0 0 1 1 1 0 Adenylate kinase, active site lid Bcr-Abl_Oligo PF09036.5 KND99918.1 - 9.5 6.2 9.9 4.9 7.1 0.3 3.3 2 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain Potass_KdpF PF09604.5 KND99919.1 - 3.5 7.5 7.5 6.8 6.6 5.2 1.4 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) Syja_N PF02383.13 KND99920.1 - 3.5e-62 210.0 0.6 7.5e-62 208.9 0.4 1.5 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 KND99920.1 - 3.8e-21 76.1 0.0 9e-21 74.9 0.0 1.6 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Sugar_tr PF00083.19 KND99922.1 - 2.7e-45 154.8 31.1 8.9e-45 153.0 21.6 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND99922.1 - 1.1e-19 70.4 33.6 6e-12 44.9 12.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 KND99922.1 - 0.00032 19.5 5.7 0.00087 18.1 3.9 1.7 1 1 0 1 1 1 1 BT1 family DUF606 PF04657.8 KND99922.1 - 0.00077 19.5 15.0 0.0018 18.3 0.4 3.8 2 2 1 3 3 3 2 Protein of unknown function, DUF606 MFS_3 PF05977.8 KND99922.1 - 0.0031 15.6 0.3 0.0031 15.6 0.2 2.5 2 1 0 2 2 2 1 Transmembrane secretion effector DUF221 PF02714.10 KND99924.1 - 5e-96 321.3 21.1 5e-96 321.3 14.6 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KND99924.1 - 4.8e-41 139.9 2.6 4.8e-41 139.9 1.8 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KND99924.1 - 7.4e-25 86.6 0.1 2.3e-24 85.0 0.1 1.9 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 KND99924.1 - 1.2e-15 57.7 2.9 1.2e-15 57.7 2.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) TMEM154 PF15102.1 KND99924.1 - 0.15 11.7 2.0 2.2 7.9 0.0 2.5 2 0 0 2 2 2 0 TMEM154 protein family RCR PF12273.3 KND99925.1 - 5.9e-39 133.6 9.0 1.8e-38 132.0 6.2 1.7 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF1443 PF07280.6 KND99925.1 - 0.17 11.4 1.2 0.28 10.7 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1443) TP6A_N PF04406.9 KND99926.1 - 1.5e-06 27.7 0.1 3.6e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Pyrophosphatase PF00719.14 KND99927.1 - 1.3e-52 177.4 0.1 1.7e-52 177.0 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Rad51 PF08423.6 KND99929.1 - 2.4e-11 43.0 1.6 2.6e-08 33.0 0.1 2.2 1 1 1 2 2 2 2 Rad51 AAA_25 PF13481.1 KND99929.1 - 1e-05 25.0 0.0 0.0001 21.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 KND99929.1 - 1.1e-05 24.7 0.1 1.9e-05 23.9 0.1 1.5 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.1 KND99929.1 - 0.047 13.8 0.1 0.17 12.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KND99929.1 - 0.058 12.9 0.1 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RecA PF00154.16 KND99929.1 - 0.093 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Maf1 PF09174.5 KND99930.1 - 3.3e-07 30.3 4.5 9.3e-07 28.8 3.2 1.8 1 1 0 1 1 1 1 Maf1 regulator 4HBT PF03061.17 KND99932.1 - 0.0073 16.4 0.0 0.18 11.9 0.0 2.4 2 0 0 2 2 2 1 Thioesterase superfamily AKAP7_NLS PF10469.4 KND99933.1 - 0.082 12.5 0.1 0.087 12.5 0.0 1.1 1 0 0 1 1 1 0 AKAP7 2'5' RNA ligase-like domain SET PF00856.23 KND99934.1 - 7.4e-11 42.6 0.0 9.8e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 SET domain NPV_P10 PF05531.7 KND99934.1 - 0.096 12.9 0.1 0.25 11.6 0.0 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Myticin-prepro PF10690.4 KND99934.1 - 1.1 9.3 4.3 13 5.9 0.3 2.5 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel 5-FTHF_cyc-lig PF01812.15 KND99935.1 - 3.6e-38 131.2 0.0 4e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Cyt-b5 PF00173.23 KND99936.1 - 6.6e-24 83.5 0.0 8.6e-24 83.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain UCH PF00443.24 KND99937.1 - 1.9e-26 92.7 7.2 2e-25 89.4 3.5 2.0 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Nitr_red_assoc PF09655.5 KND99937.1 - 0.029 14.7 0.1 0.066 13.5 0.1 1.6 1 0 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) Rota_NS6 PF04866.7 KND99937.1 - 0.037 14.0 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Rotavirus non-structural protein 6 SPX PF03105.14 KND99938.1 - 2.5e-46 158.7 5.6 2.5e-46 158.7 3.9 1.6 2 0 0 2 2 2 1 SPX domain Na_sulph_symp PF00939.14 KND99938.1 - 5.8e-19 68.3 39.6 8.9e-19 67.6 27.4 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 KND99938.1 - 3.5e-12 45.5 22.5 3.5e-12 45.5 15.6 2.1 1 1 1 2 2 2 1 Citrate transporter DUF788 PF05620.6 KND99940.1 - 8.4e-38 129.8 1.6 9.1e-38 129.7 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) PEMT PF04191.8 KND99940.1 - 2.5e-05 24.3 1.0 4e-05 23.6 0.7 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase PigN PF04987.9 KND99940.1 - 0.62 8.6 8.3 0.37 9.3 1.9 2.0 1 1 1 2 2 2 0 Phosphatidylinositolglycan class N (PIG-N) BolA PF01722.13 KND99941.1 - 6e-27 93.4 1.7 7.9e-27 93.0 1.2 1.1 1 0 0 1 1 1 1 BolA-like protein Myosin_head PF00063.16 KND99942.1 - 2.1e-217 723.4 7.0 2.1e-217 723.4 4.9 1.9 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 KND99942.1 - 3.8e-34 116.7 1.5 3.8e-34 116.7 1.0 3.0 2 0 0 2 2 2 1 DIL domain IQ PF00612.22 KND99942.1 - 3.2e-14 51.1 25.8 2.7e-05 23.3 0.1 6.8 6 0 0 6 6 6 4 IQ calmodulin-binding motif AAA_22 PF13401.1 KND99942.1 - 0.00089 19.4 0.7 0.0091 16.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain Toxin_56 PF15534.1 KND99942.1 - 0.019 15.4 0.0 0.073 13.5 0.0 2.0 1 0 0 1 1 1 0 Putative toxin 56 RNA_helicase PF00910.17 KND99942.1 - 0.1 12.8 1.7 1.1 9.4 0.0 3.2 3 0 0 3 3 3 0 RNA helicase AAA_19 PF13245.1 KND99942.1 - 0.14 11.9 0.0 0.45 10.3 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 KND99942.1 - 0.2 11.9 0.1 0.2 11.9 0.1 3.1 3 1 0 3 3 3 0 ABC transporter Peptidase_M75 PF09375.5 KND99942.1 - 0.2 10.9 8.8 0.38 10.0 6.1 1.4 1 0 0 1 1 1 0 Imelysin DUF948 PF06103.6 KND99942.1 - 1.3 8.9 10.4 0.6 10.0 0.4 3.9 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) FMN_dh PF01070.13 KND99943.1 - 8.8e-115 383.3 0.1 1.2e-114 382.9 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KND99943.1 - 3.4e-25 87.6 0.2 8.8e-25 86.3 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KND99943.1 - 3.1e-08 32.9 0.0 5.1e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KND99943.1 - 0.0018 17.2 1.1 0.0038 16.1 0.7 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KND99943.1 - 0.038 13.1 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase DUF1837 PF08878.6 KND99944.1 - 0.081 12.5 0.3 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1837) VESA1_N PF12785.2 KND99944.1 - 0.31 9.9 6.7 0.43 9.4 4.6 1.2 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 Ran-binding PF05508.6 KND99945.1 - 3.4e-79 265.8 2.5 5.2e-79 265.2 1.7 1.3 1 0 0 1 1 1 1 RanGTP-binding protein SpoIISA_toxin PF14171.1 KND99945.1 - 0.0066 15.7 0.5 0.55 9.4 0.1 2.5 2 0 0 2 2 2 2 Toxin SpoIISA, type II toxin-antitoxin system DUF2457 PF10446.4 KND99945.1 - 2.1 6.9 31.2 5 5.7 21.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SNF2_N PF00176.18 KND99946.1 - 1.9e-66 223.9 0.0 2.6e-66 223.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 KND99946.1 - 4.9e-41 140.6 1.5 7.4e-41 140.0 1.0 1.3 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 KND99946.1 - 3.7e-12 45.9 0.0 9.9e-12 44.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KND99946.1 - 1e-09 37.6 0.1 6e-09 35.1 0.0 2.2 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 KND99946.1 - 1.9e-05 24.2 0.0 3.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KND99946.1 - 0.025 14.3 0.0 0.086 12.6 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KND99946.1 - 0.072 13.2 0.0 0.39 10.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain FAD_binding_2 PF00890.19 KND99948.1 - 2.5e-77 260.4 0.0 4.2e-77 259.7 0.0 1.3 2 0 0 2 2 2 1 FAD binding domain Cyt-b5 PF00173.23 KND99948.1 - 1.1e-22 79.5 0.1 7.6e-22 76.9 0.0 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 KND99948.1 - 1.8e-12 46.8 0.1 1.7e-11 43.6 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KND99948.1 - 3.4e-09 36.8 0.0 2.4e-06 27.5 0.0 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KND99948.1 - 4.1e-08 32.7 0.0 1.6e-07 30.7 0.1 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KND99948.1 - 1e-07 31.8 0.5 6.8e-07 29.2 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KND99948.1 - 6.6e-06 24.8 0.3 0.0035 15.8 0.0 2.8 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.17 KND99948.1 - 0.00032 19.6 2.2 0.003 16.5 0.0 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KND99948.1 - 0.0019 17.3 0.2 0.0034 16.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KND99948.1 - 0.0054 16.8 0.0 0.025 14.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KND99948.1 - 0.043 12.9 0.3 1.2 8.1 0.0 2.8 3 0 0 3 3 3 0 Thi4 family Actin PF00022.14 KND99949.1 - 6.2e-152 505.5 0.0 7e-152 505.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KND99949.1 - 0.046 14.1 0.0 0.17 12.2 0.0 2.0 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Phosphodiest PF01663.17 KND99949.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase 3Beta_HSD PF01073.14 KND99953.1 - 5.6e-80 268.0 0.0 7e-80 267.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KND99953.1 - 1.9e-29 102.7 0.0 2.3e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KND99953.1 - 3.5e-18 65.4 0.0 9.3e-18 64.0 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 KND99953.1 - 1.6e-11 43.6 0.0 2.9e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KND99953.1 - 9.9e-08 32.1 0.0 1.5e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KND99953.1 - 5.6e-07 28.7 0.0 1e-06 27.8 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KND99953.1 - 2e-05 24.5 0.0 8.2e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KND99953.1 - 0.00042 20.0 0.0 0.0021 17.7 0.0 2.1 1 1 0 1 1 1 1 KR domain Mus7 PF09462.5 KND99957.1 - 3.8e-36 125.1 23.7 1.4e-28 100.1 3.5 2.6 2 1 0 3 3 3 2 Mus7/MMS22 family FliH PF02108.11 KND99957.1 - 0.043 13.6 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 Flagellar assembly protein FliH Myb_DNA-bind_6 PF13921.1 KND99958.1 - 0.002 18.2 0.6 0.0058 16.7 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KND99958.1 - 0.006 16.6 0.1 0.029 14.4 0.1 2.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain AFG1_ATPase PF03969.11 KND99959.1 - 5e-72 242.7 0.0 2.1e-68 230.7 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 KND99959.1 - 0.0002 21.4 0.3 0.73 9.7 0.5 2.4 1 1 1 2 2 2 2 AAA ATPase domain AAA PF00004.24 KND99959.1 - 0.06 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KND99959.1 - 0.15 12.2 0.0 0.49 10.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain ATG13 PF10033.4 KND99960.1 - 2e-70 236.8 0.5 2.1e-69 233.5 0.0 2.4 2 0 0 2 2 2 1 Autophagy-related protein 13 TPR_11 PF13414.1 KND99962.1 - 2.8e-36 122.9 41.3 9.2e-08 31.6 0.0 13.0 9 4 5 14 14 14 9 TPR repeat TPR_2 PF07719.12 KND99962.1 - 1e-27 93.7 40.7 5.2e-05 22.8 0.2 14.2 14 0 0 14 14 13 7 Tetratricopeptide repeat TPR_19 PF14559.1 KND99962.1 - 1.4e-27 95.7 31.1 4.5e-06 26.9 0.0 13.0 10 3 2 13 13 12 6 Tetratricopeptide repeat TPR_1 PF00515.23 KND99962.1 - 2.1e-27 93.5 37.5 5.7e-05 22.5 0.3 14.1 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_16 PF13432.1 KND99962.1 - 3.2e-26 91.3 34.9 0.00068 20.2 0.0 11.5 11 3 2 14 14 11 8 Tetratricopeptide repeat TPR_14 PF13428.1 KND99962.1 - 8.2e-25 85.0 39.5 0.005 17.3 0.0 15.1 12 4 6 18 18 15 6 Tetratricopeptide repeat TPR_17 PF13431.1 KND99962.1 - 9.4e-21 72.2 20.2 0.039 14.1 0.0 13.9 14 1 1 15 15 14 3 Tetratricopeptide repeat TPR_12 PF13424.1 KND99962.1 - 1.8e-20 72.6 32.9 0.0028 17.5 0.0 12.3 8 4 6 14 14 14 8 Tetratricopeptide repeat TPR_8 PF13181.1 KND99962.1 - 2e-18 64.7 25.6 0.00054 19.5 0.2 12.2 9 3 3 12 12 12 4 Tetratricopeptide repeat Apc3 PF12895.2 KND99962.1 - 4.7e-18 65.1 17.3 5.5e-06 26.4 0.0 8.5 7 2 2 9 9 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KND99962.1 - 3.9e-14 52.0 23.8 0.24 11.9 0.1 14.1 14 1 1 15 15 13 2 Tetratricopeptide repeat TPR_9 PF13371.1 KND99962.1 - 1e-05 25.3 11.8 0.12 12.2 0.0 7.4 6 1 1 7 7 7 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KND99962.1 - 2.7e-05 23.9 1.7 0.44 10.4 0.0 5.0 4 0 0 4 4 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 KND99962.1 - 9.4e-05 21.9 30.5 0.59 10.0 0.0 11.2 13 0 0 13 13 10 2 Tetratricopeptide repeat PPR_3 PF13812.1 KND99962.1 - 0.026 14.7 1.9 54 4.4 0.1 5.5 4 0 0 4 4 4 0 Pentatricopeptide repeat domain Sel1 PF08238.7 KND99962.1 - 0.19 12.3 15.0 9.1 7.0 0.0 7.1 10 0 0 10 10 7 0 Sel1 repeat SHNi-TPR PF10516.4 KND99962.1 - 1.9 7.7 8.8 4.4 6.6 0.0 3.7 4 0 0 4 4 4 0 SHNi-TPR TPR_4 PF07721.9 KND99962.1 - 4.4 8.0 14.0 40 5.0 0.0 6.2 5 0 0 5 5 4 0 Tetratricopeptide repeat RNA_pol_Rpc82 PF05645.8 KND99963.1 - 3.8e-53 180.6 0.1 3.8e-53 180.6 0.1 2.3 2 1 1 3 3 3 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 KND99963.1 - 2.7e-17 62.3 12.4 7e-17 61.0 0.2 4.1 5 0 0 5 5 5 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 KND99963.1 - 9.9e-06 25.0 1.1 0.052 13.0 0.2 3.2 3 0 0 3 3 3 2 TFIIE alpha subunit DUF387 PF04079.11 KND99963.1 - 0.0071 15.7 0.5 0.19 11.0 0.0 2.5 2 0 0 2 2 2 1 Putative transcriptional regulators (Ypuh-like) MIP PF00230.15 KND99964.1 - 7e-42 143.4 17.3 8.9e-42 143.0 12.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF1385 PF07136.6 KND99964.1 - 0.13 11.2 0.5 0.26 10.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) Ribosomal_60s PF00428.14 KND99967.1 - 0.27 11.6 11.6 0.38 11.1 8.0 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Mito_carr PF00153.22 KND99970.1 - 8.5e-40 134.3 10.2 7.7e-15 54.3 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF592 PF04574.8 KND99971.1 - 0.015 14.8 0.1 0.045 13.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF592) TnpV PF14198.1 KND99971.1 - 0.15 11.9 3.9 0.45 10.4 1.7 2.3 2 0 0 2 2 2 0 Transposon-encoded protein TnpV Rogdi_lz PF10259.4 KND99971.1 - 0.58 9.2 6.8 0.5 9.4 0.2 3.0 3 0 0 3 3 3 0 Rogdi leucine zipper containing protein CDC50 PF03381.10 KND99972.1 - 1.4e-98 329.4 0.5 1.8e-98 329.1 0.3 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CAF1 PF04857.15 KND99973.1 - 1e-38 133.1 1.9 1.5e-38 132.6 1.3 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease DUF1510 PF07423.6 KND99974.1 - 0.94 8.8 11.2 1.2 8.4 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BSMAP PF12280.3 KND99974.1 - 2.7 7.8 4.3 2.7 7.8 2.1 1.5 2 0 0 2 2 2 0 Brain specific membrane anchored protein NGP1NT PF08153.7 KND99975.1 - 9.6e-50 167.8 0.6 1.5e-49 167.2 0.4 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain SusD-like_3 PF14322.1 KND99975.1 - 0.0047 17.0 0.0 0.0084 16.1 0.0 1.4 1 0 0 1 1 1 1 Starch-binding associating with outer membrane MMR_HSR1 PF01926.18 KND99975.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Flavin_Reduct PF01613.13 KND99975.1 - 0.21 11.4 0.8 5.2 6.9 0.2 2.5 3 0 0 3 3 3 0 Flavin reductase like domain DUF3818 PF12825.2 KND99976.1 - 4.9e-100 334.5 19.1 1e-99 333.4 13.2 1.6 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KND99976.1 - 2.3e-32 111.4 2.4 2.3e-32 111.4 1.7 2.6 2 0 0 2 2 2 1 PX-associated PX PF00787.19 KND99976.1 - 5.3e-07 29.4 0.3 5.3e-07 29.4 0.2 3.8 3 0 0 3 3 3 1 PX domain LicD PF04991.8 KND99977.1 - 1.8e-40 139.2 0.9 1.8e-40 139.2 0.6 3.7 3 1 0 3 3 3 1 LicD family HlyIII PF03006.15 KND99978.1 - 4.7e-49 166.7 14.3 6.5e-49 166.3 9.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related Rtf2 PF04641.7 KND99979.1 - 0.026 13.7 2.7 0.024 13.8 1.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger NST1 PF13945.1 KND99979.1 - 0.21 11.6 5.1 0.24 11.4 3.5 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Sugar_tr PF00083.19 KND99982.1 - 9.5e-109 363.9 20.3 1.1e-108 363.6 14.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KND99982.1 - 4.4e-21 74.9 30.7 1.5e-16 60.0 3.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3767 PF12597.3 KND99982.1 - 0.18 11.5 0.5 0.39 10.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) DUF2798 PF11391.3 KND99983.1 - 0.027 14.1 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) Zn_clus PF00172.13 KND99984.1 - 1.5e-08 34.3 8.7 3.7e-08 33.1 6.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KND99984.1 - 3.6e-05 22.7 0.4 8.9e-05 21.4 0.3 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-PHD-like PF15446.1 KND99984.1 - 0.0041 16.4 1.9 0.0074 15.6 1.3 1.3 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain Secretin_N_2 PF07655.8 KND99985.1 - 0.4 11.0 8.6 0.53 10.7 6.0 1.1 1 0 0 1 1 1 0 Secretin N-terminal domain SR-25 PF10500.4 KND99985.1 - 7.3 5.9 12.3 9.1 5.6 8.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FUSC PF04632.7 KND99987.1 - 0.024 13.1 1.9 0.031 12.7 1.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Sybindin PF04099.7 KND99988.1 - 1.4e-33 115.5 1.0 3.9e-32 110.9 0.7 2.1 1 1 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KND99988.1 - 1.1e-09 38.2 0.1 1.4e-09 37.8 0.1 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Methyltransf_23 PF13489.1 KND99990.1 - 1.1e-15 57.7 0.0 1.6e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KND99990.1 - 7.7e-15 55.1 0.1 3.4e-14 53.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KND99990.1 - 3.8e-10 40.1 0.0 9.2e-10 38.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KND99990.1 - 4.9e-10 39.2 0.0 1.2e-09 37.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KND99990.1 - 7.7e-09 35.8 0.0 1.7e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KND99990.1 - 3.1e-07 30.9 0.0 6e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KND99990.1 - 5.8e-06 26.3 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KND99990.1 - 0.00036 19.7 0.0 0.00056 19.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.12 KND99990.1 - 0.003 16.5 0.0 1.4 7.8 0.0 2.1 2 0 0 2 2 2 2 NNMT/PNMT/TEMT family DUF3419 PF11899.3 KND99990.1 - 0.0037 16.0 0.0 0.0064 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) MTS PF05175.9 KND99990.1 - 0.016 14.5 0.0 0.052 12.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain TehB PF03848.9 KND99990.1 - 0.085 12.0 0.1 0.98 8.5 0.0 2.5 2 1 0 2 2 2 0 Tellurite resistance protein TehB APG5 PF04106.7 KND99991.1 - 2.5e-49 167.4 0.3 3.1e-49 167.1 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 YjeF_N PF03853.10 KND99995.1 - 8.3e-38 129.6 0.0 1e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Septin PF00735.13 KND99997.1 - 4e-91 304.9 0.2 8.4e-91 303.8 0.1 1.5 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KND99997.1 - 1e-05 25.4 0.0 4.5e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KND99997.1 - 0.00011 21.6 0.1 0.00044 19.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 KND99997.1 - 0.00054 19.5 0.5 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF258 PF03193.11 KND99997.1 - 0.0016 17.6 0.3 0.0043 16.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Synaptobrevin PF00957.16 KND99997.1 - 0.0032 17.0 1.2 0.0078 15.7 0.9 1.6 1 0 0 1 1 1 1 Synaptobrevin AAA_22 PF13401.1 KND99997.1 - 0.0059 16.7 0.2 0.035 14.2 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KND99997.1 - 0.0096 15.6 0.0 0.033 13.9 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain T2SE PF00437.15 KND99997.1 - 0.011 14.6 0.1 0.027 13.3 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.18 KND99997.1 - 0.011 15.5 2.8 2.5 7.9 0.0 3.3 3 0 0 3 3 3 0 Dynamin family Miro PF08477.8 KND99997.1 - 0.028 14.9 0.1 0.15 12.5 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_16 PF13191.1 KND99997.1 - 0.057 13.4 0.5 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain FeoB_N PF02421.13 KND99997.1 - 0.059 12.6 0.2 0.16 11.2 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF4570 PF15134.1 KND99997.1 - 1.3 8.8 11.2 0.47 10.3 5.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4570) HAUS6_N PF14661.1 KND99997.1 - 3.3 7.0 11.7 0.28 10.4 4.7 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus HEAT PF02985.17 KND99999.1 - 1.5e-16 58.9 12.4 5e-05 23.0 0.0 10.8 12 0 0 12 12 12 2 HEAT repeat HEAT_2 PF13646.1 KND99999.1 - 4.6e-16 58.8 4.1 0.00012 22.2 0.0 7.5 3 2 2 7 7 7 4 HEAT repeats HEAT_EZ PF13513.1 KND99999.1 - 1.4e-15 57.2 4.9 2.3e-08 34.2 0.0 7.9 9 0 0 9 9 9 1 HEAT-like repeat IBN_N PF03810.14 KND99999.1 - 2.1e-10 40.3 2.5 1.5e-09 37.6 0.1 3.6 3 1 1 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.18 KND99999.1 - 2.8e-07 30.1 2.4 0.065 13.0 0.0 5.9 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 KND99999.1 - 4.2e-05 23.0 0.3 0.25 10.6 0.0 4.0 3 1 1 4 4 4 2 CLASP N terminal TIP120 PF08623.5 KND99999.1 - 0.01 15.4 3.3 1.8 8.1 0.0 4.0 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) PAP2 PF01569.16 KNE00002.1 - 3.9e-16 58.8 1.4 5.8e-16 58.3 0.9 1.3 1 0 0 1 1 1 1 PAP2 superfamily ArfGap PF01412.13 KNE00003.1 - 1.2e-33 115.3 0.7 3.4e-33 113.9 0.0 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf adh_short_C2 PF13561.1 KNE00004.1 - 1.6e-27 96.8 0.0 2.1e-27 96.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KNE00004.1 - 1.6e-19 70.4 4.2 2.2e-19 69.9 2.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNE00004.1 - 1.2e-07 31.5 0.6 2e-07 30.8 0.4 1.3 1 0 0 1 1 1 1 KR domain SMK-1 PF04802.10 KNE00005.1 - 2.1e-42 144.8 6.4 4.5e-41 140.5 1.5 2.4 2 0 0 2 2 2 2 Component of IIS longevity pathway SMK-1 WH1 PF00568.18 KNE00005.1 - 0.027 14.1 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 WH1 domain ATP12 PF07542.6 KNE00007.1 - 5.7e-32 110.2 0.1 8.5e-32 109.6 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Prefoldin_2 PF01920.15 KNE00008.1 - 9.4e-11 41.4 2.9 1.1e-10 41.1 2.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit PP-binding_2 PF14573.1 KNE00008.1 - 0.00071 19.5 0.5 0.00087 19.2 0.4 1.3 1 0 0 1 1 1 1 Acyl-carrier IFT57 PF10498.4 KNE00008.1 - 0.0017 17.1 1.7 0.0021 16.8 1.1 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DivIVA PF05103.8 KNE00008.1 - 0.0043 17.0 4.8 0.0056 16.7 0.8 2.0 2 0 0 2 2 2 1 DivIVA protein NPV_P10 PF05531.7 KNE00008.1 - 0.019 15.1 5.0 1.1 9.4 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RTX_C PF08339.5 KNE00008.1 - 0.029 14.0 2.2 2 8.0 0.3 2.1 1 1 1 2 2 2 0 RTX C-terminal domain Laminin_II PF06009.7 KNE00008.1 - 0.045 13.5 4.2 0.15 11.7 0.5 2.0 2 0 0 2 2 2 0 Laminin Domain II Tropomyosin_1 PF12718.2 KNE00008.1 - 0.069 13.0 5.8 2 8.2 0.3 2.1 2 0 0 2 2 2 0 Tropomyosin like IL2 PF00715.12 KNE00008.1 - 0.082 12.6 1.9 0.13 11.9 1.3 1.4 1 1 0 1 1 1 0 Interleukin 2 APG6 PF04111.7 KNE00008.1 - 0.097 11.7 2.2 0.13 11.3 1.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin PF02996.12 KNE00008.1 - 0.1 12.2 6.2 0.44 10.2 0.4 2.4 2 1 1 3 3 3 0 Prefoldin subunit EzrA PF06160.7 KNE00008.1 - 0.1 10.7 4.5 0.11 10.5 0.3 1.9 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.4 KNE00008.1 - 0.13 12.1 3.9 0.54 10.1 0.3 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.7 KNE00008.1 - 0.13 12.0 9.2 0.28 10.9 2.6 2.0 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3552 PF12072.3 KNE00008.1 - 0.16 11.1 3.5 0.46 9.6 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) THOC7 PF05615.8 KNE00008.1 - 0.29 11.4 3.4 0.47 10.7 2.4 1.3 1 1 0 1 1 1 0 Tho complex subunit 7 Gon7 PF08738.5 KNE00009.1 - 2.6e-28 98.0 0.0 3e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Gon7 family 6PF2K PF01591.13 KNE00010.1 - 1.1e-54 184.8 0.0 1.6e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KNE00010.1 - 1.4e-12 48.0 0.0 4.6e-12 46.3 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 KNE00010.1 - 0.0011 19.8 0.0 0.0041 17.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KNE00010.1 - 0.015 15.1 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KNE00010.1 - 0.075 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein KOW PF00467.24 KNE00011.1 - 0.0077 15.9 1.0 0.0086 15.7 0.1 1.6 2 0 0 2 2 2 1 KOW motif TIM21 PF08294.6 KNE00012.1 - 1.2e-38 131.9 0.0 1.4e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 TIM21 Glyco_hydro_72 PF03198.9 KNE00014.1 - 3.4e-106 354.7 0.0 4.3e-106 354.4 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KNE00014.1 - 1.1e-07 32.2 0.1 2.2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 X8 domain SOBP PF15279.1 KNE00015.1 - 1.6 9.0 28.6 0.6 10.4 13.8 2.5 2 0 0 2 2 2 0 Sine oculis-binding protein Arf PF00025.16 KNE00017.1 - 5.1e-45 152.8 0.1 5.8e-45 152.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KNE00017.1 - 2.2e-11 43.3 0.0 2.6e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KNE00017.1 - 2.7e-09 36.9 0.0 4.2e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KNE00017.1 - 4.4e-09 35.5 1.5 0.00016 20.5 0.1 2.3 2 1 0 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.22 KNE00017.1 - 6.2e-08 32.2 0.0 6.5e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.17 KNE00017.1 - 8.2e-07 28.5 0.0 9.7e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNE00017.1 - 1.1e-06 29.1 0.0 1.9e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein cobW PF02492.14 KNE00017.1 - 0.014 14.8 0.1 0.061 12.7 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.5 KNE00017.1 - 0.036 13.2 0.0 0.066 12.4 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KNE00017.1 - 0.036 13.3 2.7 3.4 6.9 1.9 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.13 KNE00017.1 - 0.053 12.5 0.1 3.5 6.5 0.0 2.1 2 0 0 2 2 2 0 Septin Dynamin_N PF00350.18 KNE00017.1 - 0.059 13.1 0.2 0.71 9.6 0.0 2.3 2 1 1 3 3 3 0 Dynamin family FA_desaturase_2 PF03405.9 KNE00017.1 - 0.06 12.1 0.0 0.076 11.7 0.0 1.3 1 0 0 1 1 1 0 Fatty acid desaturase AAA_17 PF13207.1 KNE00017.1 - 0.083 13.7 0.0 0.15 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KNE00017.1 - 0.11 12.0 0.2 1 8.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain RST PF12174.3 KNE00017.1 - 0.47 10.2 2.2 0.68 9.7 0.0 2.3 2 1 1 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain DRMBL PF07522.9 KNE00018.1 - 7.5e-20 71.0 0.1 1.6e-19 69.9 0.1 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KNE00018.1 - 3.3e-06 26.7 0.1 6.5e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KNE00018.1 - 0.032 13.8 0.3 0.064 12.9 0.2 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF1751 PF08551.5 KNE00019.1 - 1.4e-25 89.5 2.6 1.4e-25 89.5 1.8 2.0 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Phageshock_PspG PF09583.5 KNE00019.1 - 0.014 15.4 0.5 0.014 15.4 0.3 3.8 4 0 0 4 4 4 0 Phage shock protein G (Phageshock_PspG) Cnl2_NKP2 PF09447.5 KNE00020.1 - 0.077 12.6 3.4 0.25 11.0 2.3 1.8 1 1 0 1 1 1 0 Cnl2/NKP2 family protein Glyco_transf_34 PF05637.7 KNE00021.1 - 2.3e-48 164.8 0.2 3e-48 164.4 0.1 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF3605 PF12239.3 KNE00021.1 - 0.015 15.1 0.5 0.035 13.9 0.0 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3605) Glucan_synthase PF02364.10 KNE00023.1 - 0 1412.7 0.9 0 1408.9 0.0 2.1 2 0 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KNE00023.1 - 4.8e-38 129.6 0.1 1.4e-37 128.2 0.1 1.9 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 eIF2A PF08662.6 KNE00024.1 - 8.7e-79 263.7 0.0 1.4e-78 263.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Sel1 PF08238.7 KNE00025.1 - 1.1e-11 44.9 12.7 9.9e-05 22.8 0.0 6.2 5 1 0 5 5 5 3 Sel1 repeat TPR_11 PF13414.1 KNE00025.1 - 0.00068 19.2 7.7 0.00088 18.8 0.4 3.3 3 0 0 3 3 3 1 TPR repeat TPR_17 PF13431.1 KNE00025.1 - 0.0072 16.4 0.5 0.091 12.9 0.0 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Lzipper-MIP1 PF14389.1 KNE00025.1 - 0.045 13.8 2.9 0.1 12.7 0.9 2.3 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 TPR_1 PF00515.23 KNE00025.1 - 0.081 12.5 4.8 1.4 8.6 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KNE00025.1 - 0.094 12.6 6.6 0.7 9.9 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat SHR3_chaperone PF08229.6 KNE00025.1 - 0.095 11.6 0.2 0.2 10.6 0.1 1.5 1 0 0 1 1 1 0 ER membrane protein SH3 TPR_8 PF13181.1 KNE00025.1 - 3.9 7.4 7.8 3.8 7.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat cIII PF08134.6 KNE00026.1 - 0.085 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 cIII protein family GATA PF00320.22 KNE00029.1 - 8.1e-15 53.8 3.7 1.6e-14 52.9 2.5 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 KNE00029.1 - 7.1e-06 25.4 0.2 1.5e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.7 KNE00029.1 - 0.0087 15.3 0.2 0.018 14.3 0.1 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding SF3b10 PF07189.6 KNE00031.1 - 1.4e-27 95.2 0.2 1.6e-27 95.1 0.1 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) E1-E2_ATPase PF00122.15 KNE00032.1 - 2.7e-67 226.1 10.9 2.7e-67 226.1 7.6 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KNE00032.1 - 7.5e-31 107.0 3.8 7.5e-31 107.0 2.6 2.8 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KNE00032.1 - 1.5e-25 90.8 0.0 7.4e-24 85.3 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KNE00032.1 - 1.5e-14 53.7 0.0 3.1e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KNE00032.1 - 3.1e-14 53.6 0.0 7.7e-14 52.2 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KNE00032.1 - 5.9e-05 22.7 0.8 0.00044 19.9 0.2 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase CAP_GLY PF01302.20 KNE00033.1 - 5.1e-16 58.1 0.6 8.5e-16 57.4 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain Mnd1 PF03962.10 KNE00033.1 - 0.0034 17.0 11.4 0.0034 17.0 7.9 5.3 1 1 3 4 4 4 2 Mnd1 family MscS_porin PF12795.2 KNE00033.1 - 5.7 6.1 75.9 0.092 12.0 13.5 3.5 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain Reo_sigmaC PF04582.7 KNE00033.1 - 8.8 5.3 21.3 1.7 7.7 2.3 3.6 1 1 4 5 5 5 0 Reovirus sigma C capsid protein Fcf2 PF08698.6 KNE00036.1 - 1.3e-32 111.7 2.6 1.3e-32 111.7 1.8 2.3 2 1 1 3 3 3 1 Fcf2 pre-rRNA processing Integrin_alpha PF00357.15 KNE00036.1 - 3.2 7.7 6.4 2.5 8.0 0.1 3.2 2 0 0 2 2 2 0 Integrin alpha cytoplasmic region zf-H2C2_2 PF13465.1 KNE00037.1 - 5.2e-06 26.4 3.5 5.2e-06 26.4 2.4 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 KNE00037.1 - 6.7e-05 22.9 11.4 0.00068 19.8 0.2 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNE00037.1 - 0.013 15.7 0.2 0.013 15.7 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KNE00037.1 - 0.12 12.6 1.0 0.39 10.9 0.7 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding tRNA-synt_2d PF01409.15 KNE00038.1 - 3e-88 295.1 0.0 4.8e-88 294.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KNE00038.1 - 5.9e-07 29.2 0.0 7.8e-07 28.8 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 KNE00038.1 - 1.8e-05 23.6 0.2 0.00046 19.0 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) Pyr_redox_dim PF02852.17 KNE00042.1 - 2.2e-41 140.2 0.1 5.9e-41 138.9 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 KNE00042.1 - 2e-36 125.7 10.9 3.4e-35 121.7 7.5 3.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KNE00042.1 - 8e-20 71.0 8.4 2.9e-18 66.0 1.1 3.7 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KNE00042.1 - 6.2e-11 42.7 0.3 4.4e-05 23.6 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KNE00042.1 - 3.4e-08 32.7 1.9 4.7e-06 25.7 0.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KNE00042.1 - 6.4e-08 32.5 2.6 0.0026 17.7 0.1 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KNE00042.1 - 9.8e-07 28.1 1.8 5.1e-05 22.5 0.0 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 KNE00042.1 - 1e-06 28.0 3.3 0.0018 17.4 0.0 2.4 2 1 0 2 2 2 2 Thi4 family DAO PF01266.19 KNE00042.1 - 2.9e-06 26.4 9.0 0.045 12.6 0.0 3.4 2 1 1 3 3 3 3 FAD dependent oxidoreductase HI0933_like PF03486.9 KNE00042.1 - 5.7e-05 21.7 7.3 0.019 13.4 0.0 3.4 3 1 1 4 4 4 2 HI0933-like protein 3HCDH_N PF02737.13 KNE00042.1 - 0.00048 19.8 0.8 0.0011 18.6 0.5 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KNE00042.1 - 0.001 17.9 0.6 0.001 17.9 0.4 2.3 2 1 1 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.14 KNE00042.1 - 0.0012 18.0 8.1 0.46 9.4 2.8 3.2 2 1 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.1 KNE00042.1 - 0.0012 17.8 0.1 1.2 7.9 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 KNE00042.1 - 0.025 14.1 0.1 0.058 12.9 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 KNE00042.1 - 0.029 13.7 0.4 0.029 13.7 0.3 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.7 KNE00042.1 - 0.052 12.4 1.7 0.98 8.2 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein Mannosyl_trans3 PF11051.3 KNE00043.1 - 1.5e-67 227.8 0.0 3.1e-67 226.7 0.0 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative L6_membrane PF05805.7 KNE00043.1 - 0.0058 16.1 0.0 0.0099 15.4 0.0 1.3 1 0 0 1 1 1 1 L6 membrane protein Ribosomal_S16 PF00886.14 KNE00043.1 - 0.13 11.9 0.1 0.63 9.7 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S16 Glycos_transf_2 PF00535.21 KNE00045.1 - 1.4e-25 89.9 0.0 1.8e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KNE00045.1 - 4.6e-13 49.5 0.0 6.7e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KNE00045.1 - 0.00036 19.7 0.0 0.0005 19.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 KNE00045.1 - 0.0012 19.0 0.0 0.0024 18.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 mRNA_triPase PF02940.10 KNE00046.1 - 1.5e-50 171.9 0.4 1.5e-50 171.9 0.3 1.6 2 0 0 2 2 2 1 mRNA capping enzyme, beta chain Iso_dh PF00180.15 KNE00047.1 - 4.2e-71 239.7 0.0 4.9e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MT-A70 PF05063.9 KNE00048.1 - 3.1e-09 36.6 0.0 1.4e-07 31.2 0.0 2.3 1 1 0 1 1 1 1 MT-A70 Voltage_CLC PF00654.15 KNE00050.1 - 3e-93 312.6 17.9 3e-93 312.6 12.4 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel Herpes_UL45 PF05473.7 KNE00050.1 - 0.041 13.2 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 UL45 protein DUF543 PF04418.7 KNE00052.1 - 1.5e-16 60.0 7.0 1.7e-16 59.9 4.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DUF4386 PF14329.1 KNE00052.1 - 0.098 12.1 0.4 0.11 11.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) Pkinase PF00069.20 KNE00053.1 - 9.6e-71 237.9 0.0 1.6e-70 237.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE00053.1 - 4.3e-48 163.6 0.3 8.2e-48 162.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 KNE00053.1 - 8.4e-11 42.1 3.9 1.7e-10 41.1 0.0 3.4 3 0 0 3 3 3 1 P21-Rho-binding domain Kinase-like PF14531.1 KNE00053.1 - 2.4e-05 23.4 0.0 4.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KNE00053.1 - 0.044 13.5 0.7 0.47 10.1 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family DSHCT PF08148.7 KNE00053.1 - 0.061 12.5 0.5 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 DSHCT (NUC185) domain DUF3484 PF11983.3 KNE00053.1 - 1.9 9.4 0.0 1.9 9.4 0.0 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3484) DNA_ligase_A_N PF04675.9 KNE00055.1 - 0.13 12.0 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 DNA ligase N terminus DUF2040 PF09745.4 KNE00056.1 - 0.0015 18.3 12.2 0.0038 17.0 5.4 2.2 1 1 0 2 2 2 2 Coiled-coil domain-containing protein 55 (DUF2040) DUF643 PF04867.7 KNE00056.1 - 0.32 11.4 3.8 0.25 11.7 1.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF643) Band_7 PF01145.20 KNE00058.1 - 2.8e-31 108.8 1.2 3.8e-31 108.3 0.8 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KNE00058.1 - 0.00065 19.2 0.1 0.00099 18.6 0.1 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family Fungal_trans_2 PF11951.3 KNE00059.1 - 3.5e-58 197.0 0.1 4.2e-58 196.7 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNE00059.1 - 0.00093 19.0 6.4 0.00093 19.0 4.5 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.13 KNE00059.1 - 0.021 13.8 0.1 5.3 5.9 0.0 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein ApbA PF02558.11 KNE00060.1 - 6.4e-27 93.8 0.1 8.7e-27 93.4 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KNE00060.1 - 1.8e-25 89.3 0.0 5.1e-25 87.8 0.1 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal AlaDh_PNT_C PF01262.16 KNE00060.1 - 0.0075 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Ldh_1_N PF00056.18 KNE00060.1 - 0.011 15.5 0.2 0.027 14.2 0.0 1.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain ThiF PF00899.16 KNE00060.1 - 0.054 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 ThiF family DAO PF01266.19 KNE00060.1 - 0.077 11.8 0.2 0.13 11.0 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KNE00060.1 - 0.086 11.6 0.3 0.15 10.8 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 KNE00060.1 - 0.14 11.1 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Aminotran_3 PF00202.16 KNE00061.1 - 1.1e-58 198.6 0.0 1.5e-58 198.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF1795 PF08786.6 KNE00061.1 - 0.022 14.6 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1795) tRNA_int_endo PF01974.12 KNE00062.1 - 1.1e-24 86.0 0.6 2.2e-24 85.0 0.1 1.7 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 KNE00062.1 - 0.056 13.0 0.6 1.6 8.3 0.3 2.5 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain DUF2992 PF11208.3 KNE00063.1 - 9.3 6.1 12.6 8.9 6.2 8.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) CBFD_NFYB_HMF PF00808.18 KNE00064.1 - 3.9e-14 52.4 2.4 5.9e-14 51.8 1.7 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KNE00064.1 - 2.7e-05 24.2 0.6 3.6e-05 23.7 0.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SpvD PF05563.7 KNE00065.1 - 0.059 12.8 0.0 0.059 12.8 0.0 1.0 1 0 0 1 1 1 0 Salmonella plasmid virulence protein SpvD FGGY_C PF02782.11 KNE00066.1 - 8.2e-54 182.2 0.3 2.3e-53 180.7 0.1 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KNE00066.1 - 1.6e-21 76.7 0.0 5e-21 75.1 0.0 1.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KNE00066.1 - 0.047 12.9 0.0 0.33 10.1 0.0 2.1 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Pecanex_C PF05041.10 KNE00066.1 - 0.12 11.4 0.0 0.25 10.3 0.0 1.5 1 0 0 1 1 1 0 Pecanex protein (C-terminus) Sulfate_transp PF00916.15 KNE00067.1 - 6.2e-79 264.9 3.1 6.2e-79 264.9 2.1 1.6 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KNE00067.1 - 4.2e-31 106.4 3.4 4.2e-31 106.4 2.4 2.4 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KNE00067.1 - 2.9e-07 29.8 0.0 6.1e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 STAS domain DEAD PF00270.24 KNE00068.1 - 8.8e-45 152.2 1.7 2.5e-44 150.7 0.6 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNE00068.1 - 1.2e-28 98.7 0.1 8.5e-28 96.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNE00068.1 - 0.00025 20.9 0.1 0.00086 19.1 0.1 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KNE00068.1 - 0.0021 18.2 0.1 0.0071 16.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KNE00068.1 - 0.0067 16.0 0.0 0.013 15.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KNE00068.1 - 0.0067 16.1 1.2 0.019 14.7 0.2 2.1 1 1 1 2 2 2 1 Part of AAA domain CMS1 PF14617.1 KNE00068.1 - 0.013 14.6 0.1 0.049 12.7 0.0 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.9 KNE00068.1 - 0.021 14.5 0.1 0.16 11.7 0.1 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain SNF2_N PF00176.18 KNE00068.1 - 0.037 12.8 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Helicase_C_2 PF13307.1 KNE00068.1 - 0.069 13.0 0.0 0.25 11.2 0.0 1.9 1 1 1 2 2 2 0 Helicase C-terminal domain Glyco_transf_8 PF01501.15 KNE00069.1 - 7.1e-24 84.5 0.0 1.8e-23 83.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 TRAP_alpha PF03896.11 KNE00069.1 - 3.5 6.5 6.5 7.5 5.4 4.5 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PI3K_1B_p101 PF10486.4 KNE00069.1 - 4.9 4.5 5.3 7.1 4.0 3.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit tRNA_U5-meth_tr PF05958.6 KNE00071.1 - 1.1e-19 70.3 0.6 1.7e-18 66.4 0.2 2.4 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.15 KNE00071.1 - 2.4e-11 43.2 0.0 4.5e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 TRAM domain Methyltransf_31 PF13847.1 KNE00071.1 - 4.8e-10 39.2 0.0 8.9e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNE00071.1 - 2e-06 28.3 0.0 5.3e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNE00071.1 - 1.5e-05 24.9 0.0 2.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KNE00071.1 - 2.3e-05 23.8 0.0 3.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.5 KNE00071.1 - 3.8e-05 23.3 0.1 8.1e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 KNE00071.1 - 6.2e-05 22.2 0.1 0.00011 21.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.11 KNE00071.1 - 0.00014 21.4 0.0 0.00028 20.5 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 KNE00071.1 - 0.00021 20.6 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KNE00071.1 - 0.00067 19.9 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNE00071.1 - 0.0021 18.4 0.0 0.007 16.8 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KNE00071.1 - 0.011 14.8 0.1 0.027 13.5 0.0 1.7 1 1 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 KNE00071.1 - 0.025 13.6 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family UPF0020 PF01170.13 KNE00071.1 - 0.043 13.3 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PAP2 PF01569.16 KNE00073.1 - 6.7e-14 51.6 6.1 2.4e-13 49.8 4.2 2.0 1 0 0 1 1 1 1 PAP2 superfamily Ras PF00071.17 KNE00074.1 - 4.4e-47 159.4 0.0 5.7e-47 159.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNE00074.1 - 9e-18 64.8 0.0 1.5e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNE00074.1 - 3.7e-08 32.8 0.0 5.9e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.1 KNE00074.1 - 0.031 14.4 0.0 0.15 12.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 KNE00074.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 KNE00074.1 - 0.12 12.0 0.1 0.24 11.0 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase DUF2401 PF10287.4 KNE00076.1 - 1.1e-95 319.6 0.4 1.1e-95 319.6 0.3 2.0 1 1 1 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 KNE00076.1 - 3.2e-31 107.2 0.1 7.8e-31 106.0 0.1 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Gryzun-like PF12742.2 KNE00077.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking FGGY_C PF02782.11 KNE00078.1 - 4.6e-07 29.6 0.0 8.1e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KNE00078.1 - 0.0014 17.9 0.2 0.003 16.8 0.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain Zn_clus PF00172.13 KNE00079.1 - 2.8e-09 36.7 11.3 4.5e-09 36.0 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain vATP-synt_E PF01991.13 KNE00080.1 - 3.7e-58 196.0 22.9 4.1e-58 195.9 15.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF2382 PF09557.5 KNE00080.1 - 0.02 14.8 1.5 0.02 14.8 1.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF2382) DUF3338 PF11819.3 KNE00080.1 - 0.93 8.9 9.0 0.33 10.3 2.9 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF3338) Asp-B-Hydro_N PF05279.6 KNE00080.1 - 7.1 6.3 18.1 0.23 11.2 6.9 2.0 1 1 1 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region CorA PF01544.13 KNE00082.1 - 2.2e-06 26.9 7.8 1.3e-05 24.4 5.4 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Phasin_2 PF09361.5 KNE00082.1 - 0.074 13.0 0.1 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Phasin protein SHS2_Rpb7-N PF03876.12 KNE00083.1 - 1.1e-13 51.1 0.0 1.8e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF1794 PF08768.6 KNE00083.1 - 0.086 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1794) PBP1_TM PF14812.1 KNE00083.1 - 2.2 8.6 5.3 4.8 7.5 3.6 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-TRM13_CCCH PF11722.3 KNE00085.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 CCCH zinc finger in TRM13 protein Mis12 PF05859.7 KNE00086.1 - 1.6e-38 131.7 0.2 3.1e-38 130.8 0.2 1.5 1 0 0 1 1 1 1 Mis12 protein GlnD_UR_UTase PF08335.6 KNE00086.1 - 0.03 14.1 0.6 0.062 13.1 0.4 1.6 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase SWIRM PF04433.12 KNE00090.1 - 3.9e-14 52.5 0.0 8.7e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Dus PF01207.12 KNE00093.1 - 4.4e-48 163.6 0.0 7.4e-48 162.9 0.0 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) COX5A PF02284.11 KNE00093.1 - 0.03 14.2 0.0 0.082 12.8 0.0 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va NCD1 PF04904.8 KNE00093.1 - 0.069 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) Tim17 PF02466.14 KNE00094.1 - 5e-27 94.4 0.2 6.2e-27 94.1 0.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Sugar_tr PF00083.19 KNE00095.1 - 9.7e-97 324.3 16.9 1.2e-96 324.0 11.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNE00095.1 - 1.8e-20 72.9 24.2 3.1e-15 55.7 5.7 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KNE00095.1 - 0.0024 16.1 1.2 0.0024 16.1 0.8 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF697 PF05128.7 KNE00095.1 - 0.02 14.4 2.0 0.043 13.2 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF697) Sugar_tr PF00083.19 KNE00098.1 - 2e-95 320.0 23.6 2.6e-95 319.6 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNE00098.1 - 1.3e-17 63.5 31.2 4.7e-13 48.5 9.3 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KNE00100.1 - 4.1e-96 322.3 22.2 5e-96 322.0 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNE00100.1 - 1.7e-22 79.6 29.3 3.1e-17 62.3 8.3 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF697 PF05128.7 KNE00100.1 - 0.15 11.5 0.8 0.33 10.4 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF697) ACC_central PF08326.7 KNE00103.1 - 7.9e-263 873.8 0.1 9.8e-263 873.4 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 KNE00103.1 - 2.2e-173 577.1 0.0 3e-173 576.7 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 KNE00103.1 - 2.3e-52 177.3 0.0 4.9e-52 176.2 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KNE00103.1 - 7.3e-26 90.4 0.1 1.5e-25 89.4 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KNE00103.1 - 2.4e-22 78.9 0.0 1.8e-20 72.9 0.0 2.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 KNE00103.1 - 2.5e-17 62.2 0.4 6.4e-17 60.9 0.3 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KNE00103.1 - 1.7e-11 44.2 0.0 6.7e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KNE00103.1 - 8.1e-09 34.6 0.0 5.3e-07 28.6 0.0 3.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 KNE00103.1 - 0.00025 20.9 0.1 0.0013 18.5 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KNE00103.1 - 0.00026 20.4 0.0 0.00068 19.0 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 KNE00103.1 - 0.014 15.0 0.2 3.9 7.1 0.0 2.6 2 0 0 2 2 2 0 Biotin-lipoyl like RnfC_N PF13375.1 KNE00103.1 - 0.1 12.3 0.1 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Peptidase_S8 PF00082.17 KNE00104.1 - 1.4e-42 145.7 1.4 1.9e-42 145.4 0.9 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KNE00104.1 - 3.4e-06 27.5 0.0 6.7e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Glucan_synthase PF02364.10 KNE00105.1 - 0 1205.2 0.8 0 1204.9 0.5 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KNE00105.1 - 1.8e-38 131.0 0.5 4.4e-38 129.7 0.4 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 TPR_11 PF13414.1 KNE00106.1 - 7.8e-19 67.0 2.0 2.3e-14 52.7 0.1 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KNE00106.1 - 1e-13 50.0 0.8 3.6e-05 23.3 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KNE00106.1 - 7.4e-12 44.3 0.8 4.2e-05 22.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat RPAP3_C PF13877.1 KNE00106.1 - 2.7e-08 33.6 1.9 3.4e-08 33.3 0.4 1.8 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 TPR_14 PF13428.1 KNE00106.1 - 1.5e-05 25.2 0.6 0.062 13.9 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KNE00106.1 - 3e-05 23.4 0.3 0.00022 20.7 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KNE00106.1 - 5.2e-05 23.8 5.9 0.0057 17.2 0.2 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KNE00106.1 - 0.00011 22.4 1.9 0.15 12.4 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KNE00106.1 - 0.00084 19.2 0.8 0.069 13.0 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KNE00106.1 - 0.0014 18.6 0.5 2.4 8.5 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KNE00106.1 - 0.0053 16.6 0.1 0.022 14.6 0.1 2.0 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 KNE00106.1 - 0.092 12.6 0.6 0.84 9.5 0.1 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 KNE00106.1 - 0.11 12.3 0.5 0.31 10.9 0.2 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 KNE00106.1 - 0.11 12.3 0.8 0.7 9.7 0.1 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat RWD PF05773.17 KNE00107.1 - 5.1e-14 52.1 0.7 5.1e-14 52.1 0.5 1.7 2 0 0 2 2 2 1 RWD domain UPF0029 PF01205.14 KNE00107.1 - 5.8e-14 51.7 0.6 9.4e-14 51.0 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 AAA_13 PF13166.1 KNE00107.1 - 0.019 13.4 1.7 0.025 13.0 1.2 1.1 1 0 0 1 1 1 0 AAA domain DNA_pol3_a_NII PF11490.3 KNE00107.1 - 0.26 10.8 6.8 0.5 9.9 4.7 1.4 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Ofd1_CTDD PF10637.4 KNE00107.1 - 0.31 10.1 3.5 0.29 10.2 1.6 1.5 1 1 1 2 2 2 0 Oxoglutarate and iron-dependent oxygenase degradation C-term UPF0029 PF01205.14 KNE00108.1 - 2.2e-11 43.4 0.0 2.4e-11 43.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF3840 PF12944.2 KNE00109.1 - 0.04 13.7 0.1 0.12 12.2 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3840) MPP6 PF10175.4 KNE00109.1 - 0.096 13.0 0.1 0.096 13.0 0.1 2.6 2 1 0 2 2 2 0 M-phase phosphoprotein 6 RasGAP_C PF03836.10 KNE00109.1 - 8.7 6.0 15.1 5.5 6.6 1.2 2.2 1 1 1 2 2 2 0 RasGAP C-terminus WD40 PF00400.27 KNE00110.1 - 2.4e-50 166.7 10.0 1e-10 41.0 0.1 11.2 12 0 0 12 12 12 7 WD domain, G-beta repeat Utp12 PF04003.7 KNE00110.1 - 1.6e-22 79.4 0.0 2.5e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 KNE00110.1 - 0.00023 19.4 0.9 2.7 6.0 0.0 4.1 3 1 0 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KNE00110.1 - 0.025 12.8 0.5 5.1 5.2 0.0 3.4 3 1 0 4 4 4 0 Cytochrome D1 heme domain Glycogen_syn PF05693.8 KNE00113.1 - 0 1109.3 0.0 0 1108.9 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 KNE00113.1 - 9.2e-08 31.6 0.0 2.9e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KNE00113.1 - 3.2e-07 30.6 0.1 9.1e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 KNE00113.1 - 7.5e-06 25.6 0.1 1.5e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain LSM PF01423.17 KNE00115.1 - 1.4e-15 56.5 0.7 2.1e-15 55.9 0.1 1.6 2 0 0 2 2 2 1 LSM domain DUF3999 PF13163.1 KNE00115.1 - 0.035 13.0 0.0 0.043 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3999) NT-C2 PF10358.4 KNE00117.1 - 8e-35 119.4 0.3 1.2e-34 118.8 0.2 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins SR-25 PF10500.4 KNE00118.1 - 0.043 13.2 7.7 0.068 12.6 5.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF59 PF01883.14 KNE00119.1 - 7.9e-07 28.9 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF59 Gryzun PF07919.7 KNE00120.1 - 1.6e-27 96.1 4.6 3.8e-27 94.8 3.2 1.7 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 KNE00120.1 - 2.3e-23 82.9 4.9 4.3e-23 82.0 3.4 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 TPR_8 PF13181.1 KNE00120.1 - 0.004 16.8 0.9 2.1 8.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KNE00120.1 - 0.015 14.8 0.1 0.051 13.2 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 KNE00120.1 - 0.053 13.4 0.2 0.38 10.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 KNE00120.1 - 0.1 12.2 0.1 0.73 9.5 0.0 2.2 2 0 0 2 2 2 0 TPR repeat TPR_21 PF09976.4 KNE00120.1 - 0.17 11.7 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat FKBP_C PF00254.23 KNE00122.1 - 6.2e-33 112.6 0.0 7.5e-33 112.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Arrestin_N PF00339.24 KNE00123.1 - 1.2e-12 47.9 0.9 1.8e-08 34.3 0.1 2.8 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain DUF2464 PF10240.4 KNE00123.1 - 0.032 13.5 0.7 0.078 12.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2464) TPR_11 PF13414.1 KNE00125.1 - 2.7e-41 139.0 24.7 4.1e-14 51.9 0.9 6.5 3 2 3 7 7 7 7 TPR repeat TPR_2 PF07719.12 KNE00125.1 - 6.6e-29 97.4 27.7 5.5e-06 25.8 0.0 10.5 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.1 KNE00125.1 - 2e-23 82.1 16.0 9.4e-07 28.6 0.0 7.8 5 2 2 8 8 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 KNE00125.1 - 6.4e-23 80.8 9.7 8.6e-06 26.2 0.0 6.1 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 KNE00125.1 - 7.3e-23 78.8 7.4 0.0014 18.6 0.0 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 KNE00125.1 - 1.3e-21 75.1 30.1 7.9e-06 25.2 0.1 10.4 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 KNE00125.1 - 5.5e-14 52.2 15.0 0.00019 21.7 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 KNE00125.1 - 7.7e-12 44.7 14.9 0.14 12.8 0.0 9.5 6 4 5 11 11 10 3 Tetratricopeptide repeat TPR_8 PF13181.1 KNE00125.1 - 1.2e-10 40.3 28.2 0.00029 20.4 0.0 9.3 8 1 1 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 KNE00125.1 - 7e-10 38.9 11.1 3.9e-06 26.8 0.1 4.9 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KNE00125.1 - 3.7e-09 35.7 8.5 0.16 11.8 0.0 7.8 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 KNE00125.1 - 1.8e-05 24.8 22.6 0.087 13.3 0.0 8.4 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_4 PF07721.9 KNE00125.1 - 0.0024 18.1 0.1 2.4 8.8 0.2 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 KNE00125.1 - 0.011 15.6 6.9 24 5.0 0.1 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat BLVR PF06375.6 KNE00125.1 - 0.017 14.9 8.5 0.018 14.8 3.4 2.4 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Exonuc_VII_S PF02609.11 KNE00125.1 - 0.042 13.6 7.3 2.5 7.9 0.1 4.2 4 0 0 4 4 4 0 Exonuclease VII small subunit BTAD PF03704.12 KNE00125.1 - 0.19 12.0 4.9 5.1 7.3 0.1 4.7 4 3 2 6 6 6 0 Bacterial transcriptional activator domain TPR_3 PF07720.7 KNE00125.1 - 0.2 11.4 0.1 0.2 11.4 0.1 4.9 5 1 1 6 6 5 0 Tetratricopeptide repeat DSPc PF00782.15 KNE00126.1 - 5.1e-07 29.3 0.1 8.4e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KNE00126.1 - 3.3e-06 26.6 0.0 5.1e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 KNE00126.1 - 0.002 17.5 0.1 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) AD PF09793.4 KNE00127.1 - 8.1e-11 41.6 2.3 2.1e-09 37.1 1.6 2.5 1 1 0 1 1 1 1 Anticodon-binding domain DUF2347 PF09804.4 KNE00127.1 - 0.25 10.6 5.3 0.31 10.2 3.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Zip PF02535.17 KNE00127.1 - 0.83 8.6 5.6 0.96 8.3 3.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_S49_N PF08496.5 KNE00127.1 - 1 9.1 5.4 1.7 8.3 3.7 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Neur_chan_memb PF02932.11 KNE00127.1 - 1.2 8.9 5.5 1.5 8.6 3.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region APG6 PF04111.7 KNE00127.1 - 1.3 8.0 9.1 1.7 7.6 6.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 YqzE PF14038.1 KNE00129.1 - 0.046 13.4 2.0 0.076 12.7 1.4 1.3 1 0 0 1 1 1 0 YqzE-like protein DUF4604 PF15377.1 KNE00129.1 - 0.079 13.1 3.4 0.09 12.9 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) OATP PF03137.15 KNE00129.1 - 0.11 10.5 0.2 0.11 10.4 0.2 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CDP-OH_P_transf PF01066.16 KNE00131.1 - 1.5e-07 31.6 13.1 1.9e-06 28.0 7.6 3.4 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Tom22 PF04281.8 KNE00132.1 - 3.5e-42 143.1 1.7 4e-42 142.9 1.2 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF3402 PF11882.3 KNE00133.1 - 2.1e-95 320.1 11.3 2.1e-95 320.1 7.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3402) N1221 PF07923.8 KNE00133.1 - 8.2e-44 149.6 4.6 1.3e-38 132.5 0.1 2.5 2 0 0 2 2 2 2 N1221-like protein Hydrolase_6 PF13344.1 KNE00134.1 - 3.9e-19 68.3 0.0 9.2e-19 67.2 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KNE00134.1 - 2.9e-12 46.1 0.0 3e-11 42.8 0.0 2.7 2 1 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 KNE00134.1 - 0.042 14.2 0.0 2.4 8.5 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Tfb2 PF03849.9 KNE00134.1 - 0.069 11.7 0.4 7.1 5.1 0.0 2.5 2 0 0 2 2 2 0 Transcription factor Tfb2 ADIP PF11559.3 KNE00135.1 - 0.00026 20.9 25.4 0.0014 18.5 7.2 2.6 2 1 0 2 2 2 2 Afadin- and alpha -actinin-Binding IncA PF04156.9 KNE00135.1 - 0.0046 16.5 31.6 0.11 12.1 5.2 2.1 2 0 0 2 2 2 2 IncA protein bZIP_1 PF00170.16 KNE00135.1 - 0.037 13.9 0.5 0.037 13.9 0.3 5.0 3 2 1 4 4 4 0 bZIP transcription factor DUF2481 PF10654.4 KNE00135.1 - 0.078 12.6 0.3 0.078 12.6 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2481) Lectin_N PF03954.9 KNE00135.1 - 0.092 12.1 10.7 0.19 11.1 1.8 3.4 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF948 PF06103.6 KNE00135.1 - 0.12 12.2 8.3 0.38 10.6 1.5 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 KNE00135.1 - 0.16 11.1 6.0 2.4 7.2 0.4 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein HrpB7 PF09486.5 KNE00135.1 - 0.19 11.6 13.5 0.26 11.2 1.8 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) COG2 PF06148.6 KNE00135.1 - 0.21 11.4 13.6 0.18 11.6 1.9 2.6 3 0 0 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1722 PF08349.6 KNE00135.1 - 0.21 11.4 7.3 2.6 7.9 0.2 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1722) DUF1664 PF07889.7 KNE00135.1 - 0.22 11.3 14.3 1.4 8.7 0.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 KNE00135.1 - 0.23 10.0 33.1 0.1 11.2 9.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein MbeD_MobD PF04899.7 KNE00135.1 - 0.27 11.1 7.4 4.3 7.3 0.1 3.0 2 1 1 3 3 2 0 MbeD/MobD like ERM PF00769.14 KNE00135.1 - 0.29 10.6 26.6 0.16 11.4 8.3 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family FUSC PF04632.7 KNE00135.1 - 0.51 8.6 1.6 0.7 8.2 1.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family GAS PF13851.1 KNE00135.1 - 0.63 9.2 32.3 0.52 9.4 4.2 2.9 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 KNE00135.1 - 0.68 9.7 35.1 0.042 13.7 4.7 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bacillus_HBL PF05791.6 KNE00135.1 - 0.91 8.8 16.5 2 7.7 2.2 3.1 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) EMP24_GP25L PF01105.19 KNE00135.1 - 1 9.0 15.0 1.1 8.9 1.9 2.3 1 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Atg14 PF10186.4 KNE00135.1 - 1.1 8.1 28.8 1 8.2 12.6 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 GLE1 PF07817.8 KNE00135.1 - 1.1 8.0 7.7 0.5 9.2 1.0 2.2 2 0 0 2 2 2 0 GLE1-like protein DUF4407 PF14362.1 KNE00135.1 - 1.2 7.9 16.0 2.2 7.1 11.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Flagellin_N PF00669.15 KNE00135.1 - 1.3 8.8 9.0 3.7 7.3 0.6 2.9 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region DUF2664 PF10867.3 KNE00135.1 - 1.5 9.4 8.4 0.98 10.0 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2664) Rotamase PF00639.16 KNE00135.1 - 1.8 9.3 9.6 1.3 9.7 1.2 2.6 2 0 0 2 2 2 0 PPIC-type PPIASE domain RRF PF01765.14 KNE00135.1 - 2.4 7.5 17.6 3.6 7.0 4.2 2.6 2 0 0 2 2 2 0 Ribosome recycling factor PEP-utilisers_N PF05524.8 KNE00135.1 - 2.6 7.8 17.2 1.2e+02 2.5 2.4 3.2 2 1 1 3 3 2 0 PEP-utilising enzyme, N-terminal DivIVA PF05103.8 KNE00135.1 - 2.8 7.9 25.6 2.6 8.0 7.2 3.1 2 1 1 3 3 3 0 DivIVA protein ATG16 PF08614.6 KNE00135.1 - 3.2 7.5 29.8 3.3 7.5 9.5 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.7 KNE00135.1 - 3.3 7.4 31.2 0.81 9.4 4.0 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Laminin_II PF06009.7 KNE00135.1 - 3.4 7.4 18.2 2.4 7.8 2.1 2.5 3 0 0 3 3 2 0 Laminin Domain II DUF4404 PF14357.1 KNE00135.1 - 3.7 8.0 22.7 0.4 11.1 1.8 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF4404) DivIC PF04977.10 KNE00135.1 - 3.8 7.0 30.9 0.61 9.6 4.5 4.0 3 1 1 4 4 4 0 Septum formation initiator DUF972 PF06156.8 KNE00135.1 - 4.3 7.7 24.8 3.2 8.1 6.8 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF972) Prominin PF05478.6 KNE00135.1 - 4.9 4.5 11.7 5 4.5 7.2 1.3 1 1 0 1 1 1 0 Prominin DUF3450 PF11932.3 KNE00135.1 - 4.9 6.3 20.0 0.38 9.9 4.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) DUF3584 PF12128.3 KNE00135.1 - 5.7 4.1 30.8 5 4.3 6.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Spectrin PF00435.16 KNE00135.1 - 6 7.2 25.3 8.8 6.6 7.6 3.4 2 2 1 3 3 2 0 Spectrin repeat Mod_r PF07200.8 KNE00135.1 - 6.2 6.7 27.9 0.079 12.8 7.1 2.6 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein APG6 PF04111.7 KNE00135.1 - 6.2 5.7 35.7 0.4 9.6 11.8 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Fib_alpha PF08702.5 KNE00135.1 - 6.2 6.9 17.0 0.77 9.8 3.1 2.5 2 1 0 3 3 2 0 Fibrinogen alpha/beta chain family PspA_IM30 PF04012.7 KNE00135.1 - 7.3 5.8 30.1 65 2.7 20.9 2.2 1 1 0 1 1 1 0 PspA/IM30 family FlxA PF14282.1 KNE00135.1 - 8.5 6.3 25.0 3.5 7.6 5.1 3.0 3 0 0 3 3 3 0 FlxA-like protein TMF_TATA_bd PF12325.3 KNE00135.1 - 8.9 6.0 31.2 0.68 9.6 4.4 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding PEX11 PF05648.9 KNE00136.1 - 4.2e-06 26.2 0.2 4.2e-06 26.2 0.2 2.1 1 1 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) SCIMP PF15050.1 KNE00136.1 - 0.1 12.4 3.8 0.25 11.2 2.7 1.6 1 0 0 1 1 1 0 SCIMP protein Dsl1_C PF11989.3 KNE00137.1 - 2.1e-15 56.6 6.6 2.1e-15 56.6 4.6 3.6 3 1 0 3 3 3 1 Retrograde transport protein Dsl1 C terminal CENP-T PF15511.1 KNE00137.1 - 1.4 8.0 9.6 2.2 7.4 6.6 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T HMA PF00403.21 KNE00138.1 - 1.1e-10 41.4 0.2 1.3e-10 41.2 0.1 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain TB2_DP1_HVA22 PF03134.14 KNE00140.1 - 1.7e-08 34.0 3.6 2.2e-08 33.6 1.6 1.8 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Ribosomal_L23 PF00276.15 KNE00141.1 - 1.2e-14 54.0 0.0 2.4e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 RNA_pol_Rpb2_6 PF00562.23 KNE00142.1 - 1.3e-126 422.4 0.1 5e-126 420.5 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KNE00142.1 - 8.7e-67 223.9 0.0 1.5e-66 223.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KNE00142.1 - 4.4e-48 163.2 0.0 9.3e-48 162.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KNE00142.1 - 3.2e-31 107.4 0.1 7.1e-31 106.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 KNE00142.1 - 3.6e-27 93.9 1.0 7.3e-27 92.9 0.7 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 KNE00142.1 - 2.8e-22 78.4 0.7 7.3e-22 77.0 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 KNE00142.1 - 5.7e-22 77.2 0.1 1.2e-21 76.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 Ribosomal_L13 PF00572.13 KNE00143.1 - 2.5e-44 150.4 0.3 3.3e-44 150.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 oligo_HPY PF08352.7 KNE00143.1 - 0.042 14.2 0.0 0.074 13.4 0.0 1.4 1 0 0 1 1 1 0 Oligopeptide/dipeptide transporter, C-terminal region SHS2_Rpb7-N PF03876.12 KNE00144.1 - 1.1e-16 60.6 0.0 1.9e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 KNE00144.1 - 5.6e-15 55.1 0.1 9.7e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 KNE00144.1 - 0.091 12.9 0.0 0.17 12.0 0.0 1.5 1 1 0 1 1 1 0 RNA polymerase III subunit Rpc25 PINIT PF14324.1 KNE00145.1 - 1.2e-29 103.2 0.2 9.5e-29 100.3 0.0 2.5 2 0 0 2 2 2 1 PINIT domain zf-MIZ PF02891.15 KNE00145.1 - 1.1e-20 72.8 3.8 2.3e-20 71.8 2.6 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KNE00145.1 - 4.6e-11 42.0 1.0 1.2e-10 40.7 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 KNE00145.1 - 4.5e-06 26.0 2.8 8e-06 25.2 1.9 1.4 1 0 0 1 1 1 1 SAP domain zf-RING_UBOX PF13445.1 KNE00145.1 - 0.05 13.3 1.9 0.19 11.4 0.2 2.5 2 0 0 2 2 2 0 RING-type zinc-finger FlbD PF06289.6 KNE00145.1 - 0.16 11.3 0.0 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 Flagellar protein (FlbD) zf-C3HC4_4 PF15227.1 KNE00145.1 - 1.3 8.9 2.4 2.5 8.0 1.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING tRNA-synt_1d PF00750.14 KNE00146.1 - 5.1e-95 318.2 2.9 6.3e-95 317.9 2.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 KNE00146.1 - 2.7e-27 95.0 0.3 6.1e-27 93.9 0.2 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 KNE00146.1 - 5.1e-05 23.7 0.2 0.00018 21.9 0.0 2.1 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain SPC25 PF06703.6 KNE00146.1 - 0.017 14.7 0.0 0.039 13.5 0.0 1.6 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF4393 PF14337.1 KNE00146.1 - 0.075 12.4 0.0 0.2 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) UBA PF00627.26 KNE00148.1 - 1.2e-09 37.7 0.0 3.5e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain P5-ATPase PF12409.3 KNE00150.1 - 2.2 8.1 6.2 16 5.3 0.1 3.1 3 0 0 3 3 3 0 P5-type ATPase cation transporter SpoV PF08183.6 KNE00156.1 - 0.44 10.3 4.9 1.9 8.3 3.4 2.1 1 1 0 1 1 1 0 Stage V sporulation protein family Gly-zipper_YMGG PF13441.1 KNE00159.1 - 0.14 11.6 9.5 0.22 11.0 6.6 1.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper Equine_IAV_S2 PF06502.6 KNE00159.1 - 0.15 11.9 1.3 0.23 11.3 0.9 1.3 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein SpoV PF08183.6 KNE00160.1 - 0.44 10.3 4.9 1.9 8.3 3.4 2.1 1 1 0 1 1 1 0 Stage V sporulation protein family Lyase_1 PF00206.15 KNE00163.1 - 2.8e-23 82.6 0.0 4.8e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 KNE00163.1 - 9.9e-16 57.5 0.1 4.2e-15 55.5 0.0 2.2 3 0 0 3 3 3 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.6 KNE00163.1 - 0.05 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) DASH_Dad3 PF08656.5 KNE00165.1 - 1e-21 76.3 1.9 1.5e-21 75.8 1.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad3 WD40 PF00400.27 KNE00168.1 - 8.8e-27 91.9 9.8 9.6e-10 37.9 0.1 6.8 6 1 0 6 6 6 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KNE00168.1 - 0.00044 19.7 0.0 0.12 11.8 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Rax2 PF12768.2 KNE00168.1 - 0.002 17.3 0.0 0.0075 15.5 0.0 1.8 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Gmad1 PF10647.4 KNE00168.1 - 0.0022 17.4 0.1 0.56 9.5 0.0 2.8 3 0 0 3 3 3 2 Lipoprotein LpqB beta-propeller domain DUF3312 PF11768.3 KNE00168.1 - 0.012 13.8 0.0 0.099 10.8 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) Cation_efflux PF01545.16 KNE00170.1 - 7e-29 100.7 16.6 8.8e-29 100.4 11.5 1.1 1 0 0 1 1 1 1 Cation efflux family Zn_clus PF00172.13 KNE00171.1 - 1.3e-05 25.0 11.2 2.5e-05 24.0 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BCA_ABC_TP_C PF12399.3 KNE00171.1 - 0.4 10.4 1.0 0.89 9.3 0.7 1.6 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter DUF2895 PF11444.3 KNE00174.1 - 0.023 13.8 1.4 0.039 13.1 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) DUF1376 PF07120.6 KNE00174.1 - 1.1 9.4 5.4 3 8.0 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1376) PIN_2 PF10130.4 KNE00174.1 - 1.3 9.1 4.0 0.33 10.9 0.2 1.8 2 0 0 2 2 2 0 PIN domain Peptidase_S64 PF08192.6 KNE00174.1 - 4.4 5.5 14.0 5.8 5.1 9.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF4613 PF15390.1 KNE00174.1 - 9.7 4.2 14.1 12 3.9 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) PGI PF00342.14 KNE00176.1 - 6.4e-220 730.6 4.1 7.4e-220 730.4 2.9 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF1892 PF08987.5 KNE00177.1 - 5.9e-30 103.6 2.4 8.3e-30 103.1 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1892) DUF4138 PF13595.1 KNE00177.1 - 0.022 13.7 0.0 0.024 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4138) P16-Arc PF04699.9 KNE00178.1 - 2.2e-51 173.8 0.0 2.6e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF4393 PF14337.1 KNE00178.1 - 0.045 13.1 0.5 0.062 12.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) AAA_22 PF13401.1 KNE00179.1 - 2.5e-05 24.4 0.0 2.5e-05 24.4 0.0 3.5 2 1 0 2 2 1 1 AAA domain T2SE PF00437.15 KNE00179.1 - 0.00031 19.7 0.0 0.00031 19.7 0.0 3.2 3 0 0 3 3 3 1 Type II/IV secretion system protein DUF812 PF05667.6 KNE00179.1 - 0.00083 17.9 29.5 0.00083 17.9 20.4 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF812) AAA_5 PF07728.9 KNE00179.1 - 0.0036 17.0 0.9 0.49 10.1 0.0 3.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KNE00179.1 - 0.0076 16.2 0.0 0.0076 16.2 0.0 3.6 2 1 0 2 2 1 1 AAA ATPase domain AAA_18 PF13238.1 KNE00179.1 - 0.01 16.1 0.0 0.01 16.1 0.0 4.0 2 1 0 2 2 1 0 AAA domain AAA_14 PF13173.1 KNE00179.1 - 0.011 15.6 0.0 0.011 15.6 0.0 3.0 3 1 0 3 3 3 0 AAA domain UPF0079 PF02367.12 KNE00179.1 - 0.012 15.1 0.4 0.045 13.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 KNE00179.1 - 0.014 15.1 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF87 PF01935.12 KNE00179.1 - 0.021 14.6 0.2 0.021 14.6 0.1 5.8 3 1 2 6 6 6 0 Domain of unknown function DUF87 AAA_29 PF13555.1 KNE00179.1 - 0.022 14.3 0.1 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 KNE00179.1 - 0.022 14.9 0.0 0.022 14.9 0.0 3.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 KNE00179.1 - 0.032 13.9 0.4 0.2 11.3 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KNE00179.1 - 0.043 13.6 0.0 0.043 13.6 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.1 KNE00179.1 - 0.046 14.0 0.0 0.046 14.0 0.0 5.6 2 1 1 3 3 2 0 AAA domain ABC_tran PF00005.22 KNE00179.1 - 0.046 14.0 0.0 0.046 14.0 0.0 4.3 2 1 1 3 3 2 0 ABC transporter RNA_helicase PF00910.17 KNE00179.1 - 0.065 13.4 0.1 0.47 10.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.1 KNE00179.1 - 0.065 14.0 0.0 0.065 14.0 0.0 3.4 2 1 0 2 2 1 0 AAA domain AAA_10 PF12846.2 KNE00179.1 - 0.072 12.5 0.0 0.072 12.5 0.0 2.9 2 1 1 3 3 1 0 AAA-like domain Nbas_N PF15492.1 KNE00179.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal FtsK_SpoIIIE PF01580.13 KNE00179.1 - 0.19 11.1 0.0 0.19 11.1 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family Reo_sigmaC PF04582.7 KNE00179.1 - 0.56 9.3 25.0 0.98 8.5 2.6 4.2 1 1 3 4 4 4 0 Reovirus sigma C capsid protein Filament PF00038.16 KNE00179.1 - 0.81 9.0 70.3 1.6 8.1 19.0 3.9 1 1 2 3 3 3 0 Intermediate filament protein Aldo_ket_red PF00248.16 KNE00180.1 - 9.8e-56 188.6 0.0 1.1e-55 188.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2380 PF09533.5 KNE00180.1 - 0.15 11.4 0.0 0.32 10.3 0.0 1.6 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) Spatacsin_C PF14649.1 KNE00180.1 - 0.18 10.6 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Spatacsin C-terminus TauD PF02668.11 KNE00181.1 - 5e-41 141.0 0.0 6.6e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 KNE00181.1 - 0.00012 22.4 0.3 0.00041 20.7 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF971) 2OG-FeII_Oxy_3 PF13640.1 KNE00181.1 - 0.031 14.7 0.0 0.28 11.7 0.0 2.4 3 0 0 3 3 3 0 2OG-Fe(II) oxygenase superfamily eIF2A PF08662.6 KNE00181.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Reticulon PF02453.12 KNE00182.1 - 0.036 13.6 0.3 0.054 13.1 0.2 1.2 1 0 0 1 1 1 0 Reticulon DUF4094 PF13334.1 KNE00182.1 - 0.22 11.9 5.8 5.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Ilm1 PF10311.4 KNE00182.1 - 0.29 10.6 3.7 0.38 10.2 2.6 1.1 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 RabGAP-TBC PF00566.13 KNE00183.1 - 3.3e-18 65.9 2.3 8.2e-18 64.6 1.6 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain NdhL PF10716.4 KNE00184.1 - 0.74 9.6 7.3 0.95 9.2 5.0 1.4 1 1 0 1 1 1 0 NADH dehydrogenase transmembrane subunit WD40 PF00400.27 KNE00185.1 - 2.8e-15 55.5 10.6 3.3e-05 23.6 0.0 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat NDK PF00334.14 KNE00187.1 - 1.8e-53 179.9 0.0 2e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase ABC_tran PF00005.22 KNE00189.1 - 1.1e-17 64.5 0.0 3e-17 63.1 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 KNE00189.1 - 4.8e-13 49.7 0.1 4.5e-06 26.8 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_15 PF13175.1 KNE00189.1 - 2.5e-07 30.1 0.0 0.019 14.0 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 KNE00189.1 - 3.7e-05 23.0 0.7 0.18 11.0 0.0 2.8 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KNE00189.1 - 0.00011 22.6 0.5 0.0003 21.1 0.3 1.9 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KNE00189.1 - 0.00021 20.5 0.0 0.00041 19.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KNE00189.1 - 0.00034 20.0 0.0 0.036 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KNE00189.1 - 0.00037 19.9 0.1 0.00075 18.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 KNE00189.1 - 0.0029 17.8 0.0 0.098 12.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KNE00189.1 - 0.0037 16.7 0.2 0.079 12.3 0.1 2.2 1 1 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 KNE00189.1 - 0.016 15.5 0.0 0.045 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KNE00189.1 - 0.026 14.4 0.2 0.1 12.4 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 KNE00189.1 - 0.029 15.1 4.3 0.26 12.0 3.0 2.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 KNE00189.1 - 0.036 13.7 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain MutS_V PF00488.16 KNE00189.1 - 0.053 12.9 0.0 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 MutS domain V AAA_22 PF13401.1 KNE00189.1 - 0.054 13.6 0.7 0.92 9.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 KNE00189.1 - 0.07 12.5 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_13 PF13166.1 KNE00189.1 - 0.081 11.3 0.1 0.11 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KNE00189.1 - 0.11 12.4 0.1 0.87 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KNE00189.1 - 0.13 11.9 0.3 0.32 10.7 0.2 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 KNE00189.1 - 0.23 10.9 1.1 0.58 9.7 0.7 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KNE00189.1 - 0.3 10.7 1.5 1.1 9.0 0.3 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MIF4G_like PF09088.6 KNE00190.1 - 2.4e-70 235.8 5.0 4e-70 235.1 1.3 2.4 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.6 KNE00190.1 - 2.3e-46 158.1 7.8 2.3e-46 158.1 5.4 2.1 2 0 0 2 2 2 1 MIF4G like MIF4G PF02854.14 KNE00190.1 - 2.8e-08 33.4 1.4 2.8e-08 33.4 1.0 3.0 4 0 0 4 4 4 1 MIF4G domain S-methyl_trans PF02574.11 KNE00191.1 - 6.8e-58 196.3 0.0 7.8e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Ytp1 PF10355.4 KNE00193.1 - 1.6e-104 348.8 10.1 2.4e-104 348.3 7.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KNE00193.1 - 7.6e-23 80.0 6.7 7.6e-23 80.0 4.6 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Pkinase PF00069.20 KNE00196.1 - 3e-58 197.0 0.4 4.8e-40 137.3 0.2 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNE00196.1 - 1.3e-26 93.2 0.9 6e-21 74.6 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 KNE00196.1 - 0.0002 21.8 0.3 0.00095 19.6 0.2 2.3 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.9 KNE00196.1 - 0.00096 18.2 0.5 0.003 16.6 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KNE00196.1 - 0.0012 17.9 0.1 0.003 16.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 KNE00196.1 - 0.0036 16.1 0.1 0.0067 15.2 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 KNE00196.1 - 0.015 15.0 0.1 0.19 11.4 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family eIF_4EBP PF05456.6 KNE00196.1 - 1.3 8.7 11.6 1.2 8.8 0.1 3.4 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) zf-BED PF02892.10 KNE00200.1 - 7.8e-07 28.7 0.1 2.4e-06 27.1 0.1 1.8 1 0 0 1 1 1 1 BED zinc finger Arc_trans_TRASH PF08394.5 KNE00200.1 - 0.032 14.3 0.7 0.062 13.4 0.5 1.4 1 0 0 1 1 1 0 Archaeal TRASH domain PyrI_C PF02748.10 KNE00200.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain NUDIX PF00293.23 KNE00203.1 - 0.00039 20.0 0.0 0.00072 19.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Trypsin_2 PF13365.1 KNE00206.1 - 2.8e-10 40.2 0.3 6.8e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.21 KNE00206.1 - 5.7e-05 22.7 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 Trypsin DUF788 PF05620.6 KNE00210.1 - 0.16 11.8 2.5 0.17 11.7 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF788) DUF4463 PF14703.1 KNE00210.1 - 0.22 12.0 6.9 0.23 11.9 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) YqfQ PF14181.1 KNE00210.1 - 0.3 11.1 6.5 0.31 11.0 4.5 1.0 1 0 0 1 1 1 0 YqfQ-like protein Vfa1 PF08432.5 KNE00210.1 - 0.32 11.0 9.3 0.35 10.8 6.5 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Med19 PF10278.4 KNE00210.1 - 0.36 10.4 8.6 0.38 10.3 5.9 1.0 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 FUSC-like PF12805.2 KNE00210.1 - 0.4 9.5 1.5 0.39 9.6 1.1 1.0 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Peptidase_S49_N PF08496.5 KNE00210.1 - 0.82 9.4 9.8 0.93 9.2 6.8 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FemAB PF02388.11 KNE00210.1 - 1.1 7.8 8.2 1.1 7.8 5.7 1.0 1 0 0 1 1 1 0 FemAB family XhlA PF10779.4 KNE00210.1 - 6.2 6.8 8.9 7.9 6.4 6.2 1.1 1 0 0 1 1 1 0 Haemolysin XhlA Na_H_Exchanger PF00999.16 KNE00215.1 - 3.6e-70 236.4 37.2 5e-70 235.9 25.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Asp-B-Hydro_N PF05279.6 KNE00216.1 - 4.8 6.9 37.8 0.1 12.3 13.5 2.7 3 0 0 3 3 3 0 Aspartyl beta-hydroxylase N-terminal region NAD_binding_10 PF13460.1 KNE00218.1 - 4.4e-09 36.6 0.0 6.7e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 NADH(P)-binding Epimerase PF01370.16 KNE00218.1 - 4.4e-05 23.0 0.0 5.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KNE00218.1 - 0.00021 20.3 0.0 0.0018 17.2 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KNE00218.1 - 0.00079 18.2 0.0 0.0012 17.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KNE00218.1 - 0.084 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase E1-E2_ATPase PF00122.15 KNE00219.1 - 1.6e-78 262.9 0.3 3.4e-78 261.8 0.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KNE00219.1 - 3.8e-44 150.3 1.6 3.8e-44 150.3 1.1 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KNE00219.1 - 8.2e-34 117.9 0.0 2.2e-33 116.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KNE00219.1 - 9.6e-16 57.5 0.0 2e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KNE00219.1 - 1.4e-14 54.7 0.0 3.5e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KNE00219.1 - 2.8e-12 45.8 0.0 6.2e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KNE00219.1 - 2.7e-09 37.0 1.9 1.6e-06 27.9 1.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Sua5_yciO_yrdC PF01300.13 KNE00222.1 - 3.4e-54 182.7 0.0 5.1e-54 182.2 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 KNE00222.1 - 1e-29 103.1 0.0 1.6e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding IBN_N PF03810.14 KNE00223.1 - 8.9e-05 22.3 0.1 0.00085 19.1 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT PF02985.17 KNE00223.1 - 0.00089 19.1 0.1 1 9.5 0.0 3.3 2 0 0 2 2 2 2 HEAT repeat Xpo1 PF08389.7 KNE00223.1 - 0.0017 18.3 0.1 0.064 13.1 0.0 3.5 2 1 0 2 2 2 1 Exportin 1-like protein PH_4 PF15404.1 KNE00226.1 - 7.5e-50 169.0 0.9 2.9e-47 160.5 0.2 3.4 2 1 0 2 2 2 1 Pleckstrin homology domain Spo7_2_N PF15407.1 KNE00226.1 - 3.6e-18 64.7 0.1 1.1e-17 63.2 0.1 1.9 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.24 KNE00226.1 - 3.5e-07 30.3 0.2 7.1e-05 22.9 0.0 2.9 2 0 0 2 2 2 1 PH domain DIM1 PF02966.11 KNE00226.1 - 0.089 12.3 1.5 35 3.9 0.0 3.4 3 0 0 3 3 3 0 Mitosis protein DIM1 zf-RING_2 PF13639.1 KNE00227.1 - 0.00013 21.7 0.2 0.00029 20.6 0.2 1.6 1 0 0 1 1 1 1 Ring finger domain C1_1 PF00130.17 KNE00227.1 - 0.076 12.7 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2413 PF10310.4 KNE00229.1 - 3.9e-107 358.8 3.8 4.4e-107 358.6 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) DUF904 PF06005.7 KNE00229.1 - 0.12 12.7 2.1 0.33 11.2 1.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF1687 PF07955.6 KNE00232.1 - 3.7e-05 23.7 0.0 7.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) CN_hydrolase PF00795.17 KNE00233.1 - 3.2e-21 75.5 0.0 5e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase BCDHK_Adom3 PF10436.4 KNE00237.1 - 1.3e-59 200.3 0.1 4e-58 195.5 0.0 2.2 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KNE00237.1 - 3.4e-15 55.7 0.0 7.5e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peroxin-13_N PF04088.8 KNE00238.1 - 5.2e-62 208.4 1.4 8.7e-62 207.7 1.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.23 KNE00238.1 - 3.7e-07 29.4 0.0 6.7e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KNE00238.1 - 4.5e-07 29.3 0.0 7.3e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KNE00238.1 - 7.5e-07 28.5 0.0 1.7e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 KNE00238.1 - 0.0011 19.1 0.1 0.0023 18.0 0.1 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain Pex2_Pex12 PF04757.9 KNE00238.1 - 0.006 16.0 0.0 0.0075 15.7 0.0 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region DUF883 PF05957.8 KNE00239.1 - 1.2e-05 25.5 27.0 0.019 15.3 4.8 3.9 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF883) EspB PF05802.6 KNE00239.1 - 0.0082 15.1 14.8 0.0082 15.1 10.2 2.1 1 1 1 2 2 2 1 Enterobacterial EspB protein PA26 PF04636.8 KNE00239.1 - 0.077 11.6 7.9 0.11 11.1 5.5 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Apolipoprotein PF01442.13 KNE00239.1 - 0.097 12.1 14.1 0.29 10.6 9.0 2.1 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain YtxH PF12732.2 KNE00239.1 - 0.38 11.1 32.9 3.8 7.9 11.3 4.1 1 1 1 2 2 2 0 YtxH-like protein Ribosomal_L22 PF00237.14 KNE00239.1 - 3.6 7.5 10.7 0.7 9.8 0.2 2.6 1 1 2 3 3 3 0 Ribosomal protein L22p/L17e Prominin PF05478.6 KNE00239.1 - 4.5 4.6 8.4 5.4 4.4 0.4 2.0 1 1 1 2 2 2 0 Prominin ISG65-75 PF11727.3 KNE00239.1 - 8.6 5.3 32.9 0.84 8.6 1.1 2.6 1 1 1 2 2 2 0 Invariant surface glycoprotein Pyr_redox_2 PF07992.9 KNE00240.1 - 1.7e-19 70.4 0.0 4.5e-19 69.1 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KNE00240.1 - 5.7e-11 42.6 1.4 2.8e-08 34.0 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KNE00240.1 - 2.9e-06 27.4 0.6 0.00011 22.3 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KNE00240.1 - 0.0003 19.8 0.3 0.0031 16.4 0.0 2.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KNE00240.1 - 0.00067 19.4 0.1 1.1 9.0 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KNE00240.1 - 0.014 14.3 0.5 0.054 12.4 0.1 1.9 1 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 KNE00240.1 - 0.066 11.6 0.7 7.3 4.9 0.1 2.7 3 0 0 3 3 3 0 HI0933-like protein HMA PF00403.21 KNE00240.1 - 0.1 12.7 1.4 9.3 6.4 0.1 3.2 3 0 0 3 3 3 0 Heavy-metal-associated domain GIDA PF01134.17 KNE00240.1 - 0.91 8.3 4.9 5 5.8 0.1 3.2 4 0 0 4 4 4 0 Glucose inhibited division protein A Lipoprotein_Ltp PF07553.6 KNE00241.1 - 0.075 12.9 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 Host cell surface-exposed lipoprotein C1_1 PF00130.17 KNE00242.1 - 0.038 13.7 0.2 0.046 13.4 0.1 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-LYAR PF08790.6 KNE00242.1 - 0.046 13.4 0.1 0.068 12.8 0.1 1.3 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger KAT11 PF08214.6 KNE00243.1 - 1.3e-67 228.3 0.0 1.7e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Histone acetylation protein AA_permease_2 PF13520.1 KNE00245.1 - 1.7e-44 152.0 49.3 2.1e-44 151.7 34.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KNE00245.1 - 1.3e-14 53.4 41.3 1.8e-14 53.0 28.6 1.1 1 0 0 1 1 1 1 Amino acid permease PLDc_N PF13396.1 KNE00245.1 - 0.25 11.0 5.5 0.34 10.6 2.0 2.6 2 0 0 2 2 2 0 Phospholipase_D-nuclease N-terminal Pyridox_oxase_2 PF12766.2 KNE00246.1 - 7.1e-29 100.0 0.0 1.2e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 KNE00246.1 - 1.8e-06 27.8 0.2 3.7e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase DHFR_1 PF00186.14 KNE00248.1 - 1.5e-30 105.8 0.0 1.8e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Dihydrofolate reductase DSPc PF00782.15 KNE00249.1 - 3e-12 46.2 0.1 3.4e-11 42.8 0.0 2.7 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KNE00249.1 - 0.009 15.3 0.0 0.022 14.1 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase YqeY PF09424.5 KNE00251.1 - 1.3e-21 77.0 4.8 1.5e-21 76.7 3.3 1.1 1 0 0 1 1 1 1 Yqey-like protein Imm16 PF15565.1 KNE00251.1 - 0.016 15.0 0.9 0.14 11.9 0.1 2.1 2 1 0 2 2 2 0 Immunity protein 16 Herpes_BLRF2 PF05812.7 KNE00251.1 - 0.017 14.9 2.4 0.023 14.4 0.8 1.7 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein FANCF PF11107.3 KNE00251.1 - 0.045 13.0 1.1 0.054 12.7 0.8 1.1 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) Snf7 PF03357.16 KNE00251.1 - 0.048 13.0 3.4 0.084 12.2 2.4 1.5 1 1 0 1 1 1 0 Snf7 UPF0154 PF03672.8 KNE00251.1 - 0.086 12.4 0.3 1 9.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) ApoC-I PF04691.7 KNE00251.1 - 0.089 12.5 0.6 0.089 12.5 0.4 1.9 2 1 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) CM_1 PF07736.6 KNE00251.1 - 0.11 12.5 2.3 2.7 8.1 0.1 2.3 1 1 0 2 2 2 0 Chorismate mutase type I PP2C_C PF07830.8 KNE00251.1 - 1.5 9.0 4.8 16 5.6 0.3 2.7 1 1 1 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain FtsK_SpoIIIE PF01580.13 KNE00252.1 - 0.042 13.3 0.6 0.048 13.1 0.4 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family RE_LlaJI PF09563.5 KNE00252.1 - 0.21 10.2 0.6 0.25 9.9 0.4 1.0 1 0 0 1 1 1 0 LlaJI restriction endonuclease YEATS PF03366.11 KNE00254.1 - 7.2e-26 89.7 0.0 1.4e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 YEATS family FlgM PF04316.8 KNE00254.1 - 0.08 12.8 0.0 3.1 7.8 0.0 2.5 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM WD40 PF00400.27 KNE00255.1 - 4.5e-34 115.0 12.3 1.4e-06 27.9 0.2 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KNE00255.1 - 0.0004 19.2 1.3 0.33 9.6 0.0 3.9 2 2 1 4 4 4 2 Nup133 N terminal like TRF PF08558.5 KNE00256.1 - 2.1e-90 302.2 0.0 3.1e-90 301.7 0.0 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 KNE00256.1 - 6.9e-08 32.4 0.5 1.6e-07 31.2 0.4 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KNE00256.1 - 0.0041 17.2 0.0 0.01 15.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Aminotran_3 PF00202.16 KNE00258.1 - 5.3e-87 291.8 0.0 6.2e-87 291.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KNE00258.1 - 0.0056 15.6 0.0 0.0094 14.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Mito_carr PF00153.22 KNE00259.1 - 3e-67 222.3 0.6 6.9e-25 86.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.8 KNE00259.1 - 0.4 10.2 3.3 2.8 7.5 0.1 2.6 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif B12D PF06522.6 KNE00260.1 - 3e-06 26.8 0.0 4e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Transcrip_reg PF01709.15 KNE00261.1 - 7.3e-67 224.9 3.8 8.3e-67 224.7 2.6 1.0 1 0 0 1 1 1 1 Transcriptional regulator OsmC PF02566.14 KNE00261.1 - 0.07 13.3 0.3 0.91 9.7 0.0 2.5 3 0 0 3 3 3 0 OsmC-like protein ATP-synt_F PF01990.12 KNE00262.1 - 1.4e-31 108.7 0.1 1.6e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit BRCT PF00533.21 KNE00263.1 - 1e-10 41.6 0.6 2.6e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KNE00263.1 - 5.1e-06 26.2 0.0 1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain DUF3006 PF11213.3 KNE00263.1 - 0.0013 18.3 0.1 0.0049 16.5 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) Sds3 PF08598.6 KNE00264.1 - 2.2e-39 135.1 0.1 2.2e-39 135.1 0.1 2.3 2 1 0 2 2 2 1 Sds3-like PPPI_inhib PF14895.1 KNE00267.1 - 0.0066 15.2 0.0 0.0067 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 1 inhibitor RRM_1 PF00076.17 KNE00268.1 - 1.6e-15 56.4 1.1 6.5e-11 41.7 0.1 4.0 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNE00268.1 - 4.5e-11 42.5 0.7 1.9e-08 34.1 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNE00268.1 - 5.9e-06 26.0 0.1 0.0046 16.7 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KBP_C PF12309.3 KNE00268.1 - 0.057 12.3 14.9 0.097 11.6 10.3 1.3 1 0 0 1 1 1 0 KIF-1 binding protein C terminal Spo7_2_N PF15407.1 KNE00268.1 - 0.089 12.2 0.0 0.35 10.3 0.0 2.0 1 0 0 1 1 1 0 Sporulation protein family 7 Peptidase_C1_2 PF03051.10 KNE00269.1 - 5.1e-157 522.8 2.6 5.9e-157 522.6 1.8 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 KNE00269.1 - 8.9e-06 25.7 1.4 0.0019 18.1 0.9 2.6 2 1 0 2 2 2 2 Papain family cysteine protease DUF2258 PF10015.4 KNE00269.1 - 0.087 12.6 0.1 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) COG4 PF08318.7 KNE00270.1 - 2.6e-102 342.0 5.0 2.6e-102 342.0 3.5 2.0 2 0 0 2 2 2 1 COG4 transport protein L27_N PF09060.5 KNE00270.1 - 0.045 13.5 0.2 0.13 12.1 0.2 1.8 1 0 0 1 1 1 0 L27_N DUF1664 PF07889.7 KNE00270.1 - 0.13 12.0 1.4 0.61 9.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Phage_tail_T PF06223.7 KNE00270.1 - 0.2 12.0 1.3 2.1 8.7 0.1 2.9 2 1 0 2 2 2 0 Minor tail protein T zf-CCCH PF00642.19 KNE00271.1 - 4.6e-09 35.7 26.8 0.0025 17.4 0.7 4.4 4 1 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KNE00271.1 - 0.077 13.0 29.8 0.23 11.5 1.1 5.1 4 1 1 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type FAD_binding_2 PF00890.19 KNE00272.1 - 5.3e-76 256.1 0.2 6e-76 255.9 0.2 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KNE00272.1 - 1.4e-11 43.9 0.3 3e-07 29.7 0.2 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KNE00272.1 - 1.9e-11 44.2 0.0 4.4e-09 36.4 0.0 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KNE00272.1 - 1.4e-07 31.0 0.4 2.8e-07 30.0 0.3 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KNE00272.1 - 1.9e-07 30.9 0.4 5.6e-07 29.4 0.1 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KNE00272.1 - 2.2e-07 31.1 0.0 8.3e-06 26.0 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KNE00272.1 - 1.4e-06 27.0 5.0 0.0033 15.9 0.2 3.2 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox PF00070.22 KNE00272.1 - 3.2e-05 24.2 0.2 0.0014 19.0 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KNE00272.1 - 4e-05 22.6 0.3 0.00044 19.2 0.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KNE00272.1 - 0.00017 20.8 0.8 0.00026 20.1 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KNE00272.1 - 0.00018 20.6 2.0 0.00055 19.1 0.3 2.2 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 KNE00272.1 - 0.0007 18.6 0.3 0.0011 18.0 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DUF1919 PF08942.5 KNE00272.1 - 0.071 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1919) Amino_oxidase PF01593.19 KNE00272.1 - 0.088 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 KNE00272.1 - 0.1 12.2 0.1 0.61 9.7 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Spo7 PF03907.8 KNE00273.1 - 6.9e-71 238.1 2.0 9.3e-71 237.7 1.4 1.1 1 0 0 1 1 1 1 Spo7-like protein GWT1 PF06423.7 KNE00274.1 - 1.5e-39 135.2 7.9 2.5e-39 134.5 4.2 2.3 2 0 0 2 2 2 1 GWT1 Oxysterol_BP PF01237.13 KNE00275.1 - 6.3e-93 311.0 0.2 7e-93 310.9 0.2 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Ribosomal_L35Ae PF01247.13 KNE00276.1 - 3.4e-43 145.3 1.5 3.8e-43 145.1 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 KNE00276.1 - 0.0056 16.5 0.1 3.1 7.7 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain GRAB PF10375.4 KNE00277.1 - 1.9e-06 27.2 2.0 4.1e-06 26.2 1.4 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain ATG16 PF08614.6 KNE00277.1 - 2.1e-05 24.4 56.7 0.00081 19.2 19.9 2.5 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DUF904 PF06005.7 KNE00277.1 - 0.00057 20.1 2.0 0.00057 20.1 1.4 6.4 2 1 2 4 4 3 2 Protein of unknown function (DUF904) Filament PF00038.16 KNE00277.1 - 0.0016 17.9 22.9 0.0016 17.9 15.9 3.1 1 1 2 3 3 3 2 Intermediate filament protein DUF972 PF06156.8 KNE00277.1 - 0.016 15.5 8.8 0.016 15.5 6.1 4.6 1 1 4 5 5 5 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 KNE00277.1 - 0.036 12.5 47.6 0.22 9.9 7.9 2.1 1 1 1 2 2 2 0 AAA domain Reo_sigmaC PF04582.7 KNE00277.1 - 0.11 11.6 13.8 0.26 10.4 0.8 2.8 1 1 2 3 3 3 0 Reovirus sigma C capsid protein APG6 PF04111.7 KNE00277.1 - 0.74 8.8 59.1 0.12 11.3 20.0 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF3450 PF11932.3 KNE00277.1 - 2.6 7.2 43.7 0.3 10.3 8.2 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) CCDC155 PF14662.1 KNE00277.1 - 5.1 6.6 63.9 0.24 10.9 13.2 3.6 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 GAS PF13851.1 KNE00277.1 - 8.9 5.4 63.1 0.03 13.5 12.0 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Phage_portal PF04860.7 KNE00278.1 - 0.023 13.3 0.2 0.024 13.3 0.1 1.0 1 0 0 1 1 1 0 Phage portal protein RFC1 PF08519.7 KNE00279.1 - 1.6e-52 177.3 0.8 2.9e-52 176.5 0.1 1.8 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.24 KNE00279.1 - 4.7e-11 43.0 0.0 1.5e-10 41.3 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KNE00279.1 - 6.9e-08 31.6 0.1 1.1e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 KNE00279.1 - 3.2e-06 27.9 1.6 5.8e-06 27.1 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 KNE00279.1 - 4.4e-05 23.6 0.0 0.00019 21.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KNE00279.1 - 8.3e-05 21.7 0.0 0.00019 20.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KNE00279.1 - 0.00017 21.6 0.6 0.00091 19.2 0.0 2.6 1 1 2 3 3 3 1 AAA ATPase domain DNA_pol3_delta PF06144.8 KNE00279.1 - 0.00036 20.0 0.0 0.00079 18.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 KNE00279.1 - 0.00038 20.3 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KNE00279.1 - 0.0023 18.1 0.1 0.012 15.7 0.0 2.4 2 1 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 KNE00279.1 - 0.0023 18.2 0.0 0.0023 18.2 0.0 2.5 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 KNE00279.1 - 0.0048 16.7 0.0 0.019 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KNE00279.1 - 0.0097 15.6 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 KNE00279.1 - 0.013 15.0 0.1 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.10 KNE00279.1 - 0.038 13.6 0.2 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 NTPase DEAD PF00270.24 KNE00279.1 - 0.057 12.9 0.1 5.7 6.4 0.1 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase NACHT PF05729.7 KNE00279.1 - 0.066 12.8 0.0 0.35 10.5 0.0 2.3 1 1 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 KNE00279.1 - 0.1 12.2 0.2 0.88 9.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KNE00279.1 - 0.11 12.4 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.1 KNE00279.1 - 0.97 8.9 6.6 0.33 10.5 0.0 2.8 2 1 0 2 2 2 0 AAA domain DUF3987 PF13148.1 KNE00279.1 - 2.9 6.3 10.0 9.3 4.6 5.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Pkinase PF00069.20 KNE00280.1 - 4.2e-68 229.3 0.0 6.2e-68 228.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE00280.1 - 6.8e-38 130.2 0.0 1e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNE00280.1 - 3.9e-07 29.3 0.0 9.6e-07 28.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 KNE00280.1 - 3.2e-05 22.9 0.1 4.9e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 KNE00280.1 - 0.0026 17.5 1.5 0.014 15.1 1.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KNE00280.1 - 0.031 13.3 0.3 0.077 12.0 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nop53 PF07767.6 KNE00282.1 - 1.3e-75 254.8 44.6 1.5e-75 254.6 30.9 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF479 PF04336.7 KNE00282.1 - 0.57 10.3 4.5 0.48 10.5 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF479 FHIPEP PF00771.15 KNE00282.1 - 4.2 5.5 5.8 7.5 4.7 4.0 1.4 1 0 0 1 1 1 0 FHIPEP family chaperone_DMP PF10448.4 KNE00284.1 - 2.5e-05 24.2 0.0 2.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 20S proteasome chaperone DUF4397 PF14344.1 KNE00284.1 - 0.1 12.8 0.2 0.14 12.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4397) RRM_1 PF00076.17 KNE00286.1 - 0.0037 16.8 1.1 0.36 10.4 0.0 3.1 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAM2 PF07145.10 KNE00286.1 - 0.68 9.5 4.2 0.72 9.4 0.4 2.6 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Nfu_N PF08712.6 KNE00287.1 - 3.9e-28 96.9 0.0 7.8e-28 95.9 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 KNE00287.1 - 3.5e-21 74.7 0.0 5.4e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain Pox_C4_C10 PF03336.8 KNE00287.1 - 0.073 11.8 0.1 0.099 11.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus C4/C10 protein SNF2_N PF00176.18 KNE00288.1 - 1.9e-66 223.8 0.3 2.9e-66 223.2 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KNE00288.1 - 6.3e-15 54.8 0.0 1.1e-13 50.8 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNE00288.1 - 2.4e-10 40.5 0.2 1.2e-09 38.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RCC1 PF00415.13 KNE00289.1 - 1.7e-22 79.3 14.6 0.00028 21.0 0.2 7.2 6 2 1 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KNE00289.1 - 2.4e-16 58.8 22.1 1.1e-08 34.4 0.0 6.0 7 1 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat DUF775 PF05603.7 KNE00290.1 - 2.3e-63 213.3 0.2 2.6e-63 213.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) DUF2486 PF10667.4 KNE00290.1 - 0.042 14.3 0.2 0.059 13.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) Alb1 PF09135.6 KNE00297.1 - 9.8e-14 51.9 6.3 9.8e-14 51.9 4.4 1.5 2 0 0 2 2 2 1 Alb1 Med3 PF11593.3 KNE00297.1 - 0.12 11.5 3.8 0.13 11.4 2.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribul_P_3_epim PF00834.14 KNE00298.1 - 1.2e-66 223.7 0.0 1.4e-66 223.4 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PcrB PF01884.12 KNE00298.1 - 0.038 13.2 0.0 0.069 12.3 0.0 1.4 1 0 0 1 1 1 0 PcrB family OMPdecase PF00215.19 KNE00298.1 - 0.074 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Ring_hydroxyl_A PF00848.14 KNE00298.1 - 0.15 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) MFS_1 PF07690.11 KNE00300.1 - 2.2e-25 89.1 21.2 2.2e-25 89.1 14.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KNE00300.1 - 0.00011 20.9 3.4 0.00011 20.9 2.3 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter Ank PF00023.25 KNE00301.1 - 2.9e-09 36.2 0.0 0.00049 19.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KNE00301.1 - 5.9e-08 32.9 0.0 1.7e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KNE00301.1 - 7.3e-08 32.7 0.0 0.025 15.1 0.0 2.7 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNE00301.1 - 1.1e-06 28.3 0.0 0.023 14.8 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KNE00301.1 - 1.6e-06 28.1 0.0 0.00033 20.7 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) HATPase_c_2 PF13581.1 KNE00301.1 - 0.0014 18.4 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain A_deamin PF02137.13 KNE00302.1 - 2.6e-56 191.4 0.0 3.1e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Fis1_TPR_C PF14853.1 KNE00303.1 - 3.1e-23 81.3 0.4 7.1e-23 80.2 0.2 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 KNE00303.1 - 4.4e-12 45.0 0.0 8.1e-12 44.2 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 KNE00303.1 - 0.0011 18.6 1.1 0.004 16.9 0.7 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KNE00303.1 - 0.0039 17.4 1.3 0.19 12.0 0.3 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KNE00303.1 - 0.0072 16.9 0.6 0.46 11.2 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KNE00303.1 - 0.021 15.2 1.5 0.075 13.5 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KNE00303.1 - 0.073 13.7 0.3 0.25 12.0 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 KNE00303.1 - 0.41 10.9 3.8 15 6.0 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Alg6_Alg8 PF03155.10 KNE00304.1 - 4.9e-140 467.4 41.3 6.1e-140 467.1 28.6 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family TPP_enzyme_M PF00205.17 KNE00305.1 - 1.5e-27 96.0 0.0 5.1e-27 94.2 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 KNE00305.1 - 4e-27 94.7 0.0 7.4e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KNE00305.1 - 1.2e-15 57.3 0.0 2.1e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 KNE00305.1 - 0.031 13.8 0.0 0.095 12.2 0.0 1.9 2 0 0 2 2 2 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Fungal_trans PF04082.13 KNE00306.1 - 3.5e-29 101.4 4.7 7e-29 100.4 3.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNE00306.1 - 5.4e-10 39.0 7.9 9.1e-10 38.2 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aa_trans PF01490.13 KNE00307.1 - 7.6e-79 265.0 33.6 9e-79 264.8 23.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 KNE00307.1 - 1.1e-05 24.1 37.4 1.7e-05 23.5 25.9 1.3 1 1 0 1 1 1 1 Amino acid permease DNA_ligase_A_M PF01068.16 KNE00308.1 - 1.1e-42 145.6 0.5 2.6e-42 144.5 0.3 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KNE00308.1 - 3.9e-25 88.6 0.1 1.2e-24 87.1 0.0 1.9 1 1 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KNE00308.1 - 1.3e-06 28.7 0.0 3.7e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 KNE00308.1 - 1.5e-06 28.2 0.0 0.0016 18.5 0.0 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.14 KNE00308.1 - 3e-05 23.8 0.7 0.099 12.3 0.0 2.5 2 0 0 2 2 2 2 mRNA capping enzyme, catalytic domain DUF1752 PF08550.5 KNE00312.1 - 5.9e-05 22.5 0.4 0.00012 21.6 0.3 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Ded_cyto PF06920.8 KNE00318.1 - 0.13 11.5 0.4 0.73 9.1 0.3 1.9 1 1 0 1 1 1 0 Dedicator of cytokinesis DEAD PF00270.24 KNE00319.1 - 1.3e-20 73.5 0.0 1.9e-17 63.3 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KNE00319.1 - 3.3e-20 71.7 0.1 1.1e-19 70.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNE00319.1 - 4.7e-18 65.6 6.1 1.6e-17 63.9 0.0 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KNE00319.1 - 0.048 13.7 0.0 0.31 11.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain DUF506 PF04720.7 KNE00319.1 - 0.39 10.3 5.8 4.3 6.9 0.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF506) PUA PF01472.15 KNE00321.1 - 1.8e-18 66.0 0.1 2.9e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 PUA domain BBS2_N PF14781.1 KNE00321.1 - 0.061 12.9 0.1 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal CAP_GLY PF01302.20 KNE00322.1 - 1.2e-17 63.3 0.0 3e-17 62.0 0.1 1.6 2 0 0 2 2 2 1 CAP-Gly domain LRR_4 PF12799.2 KNE00322.1 - 2.8e-15 55.5 4.7 0.00074 19.0 0.1 5.6 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KNE00322.1 - 1.3e-08 33.7 11.5 1.5 9.1 0.2 8.0 5 3 2 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.1 KNE00322.1 - 7.7e-07 28.7 6.1 0.026 14.2 1.2 3.9 2 2 1 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 KNE00322.1 - 1.7e-06 27.5 7.6 23 5.4 0.1 7.7 7 1 0 7 7 7 0 Leucine Rich repeat LRR_7 PF13504.1 KNE00322.1 - 2.2e-05 23.9 12.5 22 5.8 0.1 8.3 9 0 0 9 9 9 0 Leucine rich repeat Ubiquitin_2 PF14560.1 KNE00322.1 - 7.5e-05 22.9 0.0 0.00018 21.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain GN3L_Grn1 PF08701.6 KNE00323.1 - 1e-25 89.4 14.4 2.4e-25 88.2 10.0 1.7 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 KNE00323.1 - 1.7e-21 76.2 0.5 4.9e-16 58.7 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KNE00323.1 - 9.5e-11 41.2 0.2 3.9e-09 35.9 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KNE00323.1 - 4.8e-06 26.1 0.0 0.003 17.0 0.0 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KNE00323.1 - 7.3e-05 22.6 4.5 0.43 10.3 0.7 3.8 2 2 1 3 3 3 2 Dynamin family Miro PF08477.8 KNE00323.1 - 0.0012 19.3 0.1 0.36 11.3 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 KNE00323.1 - 0.0018 17.4 0.0 0.0037 16.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ArgK PF03308.11 KNE00323.1 - 0.033 12.9 0.0 0.033 12.9 0.0 1.8 2 0 0 2 2 2 0 ArgK protein cobW PF02492.14 KNE00323.1 - 0.048 13.0 0.3 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 KNE00323.1 - 0.1 13.3 0.0 0.1 13.3 0.0 2.9 2 2 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KNE00323.1 - 0.16 12.2 4.5 0.28 11.4 0.0 3.0 3 1 0 3 3 3 0 AAA domain Nop14 PF04147.7 KNE00324.1 - 0.0063 14.5 4.5 0.0064 14.4 3.1 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 KNE00324.1 - 0.0064 14.5 0.3 0.0064 14.5 0.2 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF2457 PF10446.4 KNE00324.1 - 0.0081 14.9 8.8 0.0087 14.8 6.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.7 KNE00324.1 - 0.028 14.1 5.3 0.032 13.9 3.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sporozoite_P67 PF05642.6 KNE00324.1 - 0.028 12.2 1.7 0.032 12.1 1.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CobT PF06213.7 KNE00324.1 - 0.037 13.1 5.2 0.043 12.9 3.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Daxx PF03344.10 KNE00324.1 - 0.1 11.0 4.3 0.1 11.0 3.0 1.1 1 0 0 1 1 1 0 Daxx Family PBP1_TM PF14812.1 KNE00324.1 - 0.11 12.8 7.8 0.22 11.8 5.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 KNE00324.1 - 0.11 12.0 6.6 0.18 11.4 4.6 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 KNE00324.1 - 0.26 10.5 9.2 0.29 10.3 6.4 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2076 PF09849.4 KNE00324.1 - 0.55 10.2 5.0 0.66 9.9 3.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Nucleoplasmin PF03066.10 KNE00324.1 - 1.8 8.0 12.1 2.7 7.4 8.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 KNE00324.1 - 9.9 5.9 6.9 16 5.2 4.8 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal GDA1_CD39 PF01150.12 KNE00325.1 - 7.7e-122 406.9 0.0 1.1e-121 406.4 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family BRO1 PF03097.13 KNE00326.1 - 0.00066 18.5 0.3 0.0037 16.0 0.0 2.2 2 1 0 2 2 2 1 BRO1-like domain EF1_GNE PF00736.14 KNE00327.1 - 2.6e-20 71.9 0.2 2.8e-20 71.8 0.2 1.0 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain DNA_pol3_a_NII PF11490.3 KNE00327.1 - 0.074 12.6 0.1 0.081 12.5 0.1 1.0 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II N6-adenineMlase PF10237.4 KNE00329.1 - 7.6e-56 188.2 0.0 9.8e-56 187.8 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase TraL PF07178.6 KNE00329.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 TraL protein B-block_TFIIIC PF04182.7 KNE00330.1 - 1.1e-11 44.3 0.1 4.8e-10 39.1 0.0 3.1 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC MarR_2 PF12802.2 KNE00330.1 - 0.038 13.6 0.3 0.15 11.7 0.2 2.1 1 0 0 1 1 1 0 MarR family G-patch PF01585.18 KNE00331.1 - 1.2e-12 47.4 0.1 2.7e-12 46.2 0.1 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KNE00331.1 - 3e-05 23.8 0.2 3e-05 23.8 0.1 4.1 2 1 0 2 2 2 1 DExH-box splicing factor binding site CDC27 PF09507.5 KNE00331.1 - 0.025 13.8 43.9 0.029 13.5 30.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SprA-related PF12118.3 KNE00331.1 - 0.1 11.9 22.5 0.13 11.5 15.6 1.3 1 0 0 1 1 1 0 SprA-related family PLRV_ORF5 PF01690.12 KNE00331.1 - 8.1 5.4 26.1 11 5.0 18.1 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Glyco_hydro_72 PF03198.9 KNE00332.1 - 2.7e-135 450.3 9.6 3.5e-135 450.0 6.6 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KNE00332.1 - 5.8e-24 84.3 4.2 5.8e-24 84.3 2.9 2.1 2 0 0 2 2 2 1 X8 domain Glyco_hydro_2_C PF02836.12 KNE00332.1 - 3.2e-05 22.9 0.9 5e-05 22.3 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 KNE00332.1 - 0.00013 21.3 0.7 0.0052 16.0 0.5 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF3454 PF11936.3 KNE00334.1 - 0.0037 17.4 0.0 0.012 15.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3454) Trypan_PARP PF05887.6 KNE00335.1 - 0.00068 19.4 14.7 0.00074 19.3 10.2 1.1 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.8 KNE00335.1 - 0.45 8.8 6.4 0.51 8.6 4.4 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Gsf2 PF11055.3 KNE00338.1 - 4.7e-139 463.0 0.2 5.5e-139 462.8 0.1 1.0 1 0 0 1 1 1 1 Glucose signalling factor 2 Sad1_UNC PF07738.8 KNE00338.1 - 0.051 13.3 0.0 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 Sad1 / UNC-like C-terminal Meth_synt_2 PF01717.13 KNE00339.1 - 7e-143 475.4 0.0 1.7e-137 457.7 0.0 2.6 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KNE00339.1 - 4.7e-123 410.3 0.2 1.7e-111 372.4 0.1 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.4 KNE00339.1 - 5.2 6.6 5.8 0.73 9.3 0.0 2.7 3 0 0 3 3 3 0 Short C-terminal domain SEP PF08059.8 KNE00341.1 - 1.2e-27 96.0 0.0 3.2e-27 94.6 0.0 1.8 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 KNE00341.1 - 2.9e-15 56.0 0.0 6.5e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 KNE00341.1 - 1e-10 40.9 0.6 2e-10 40.0 0.4 1.5 1 0 0 1 1 1 1 UBA-like domain RNB PF00773.14 KNE00342.1 - 0.0099 15.1 0.1 0.033 13.4 0.1 1.9 1 1 0 1 1 1 1 RNB domain Chorismate_bind PF00425.13 KNE00343.1 - 2.7e-90 302.1 0.0 3.7e-90 301.7 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme POR PF01558.13 KNE00343.1 - 0.008 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase DUF2312 PF10073.4 KNE00343.1 - 0.0094 15.2 0.2 0.042 13.1 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2312) Anth_synt_I_N PF04715.8 KNE00343.1 - 0.011 15.6 2.6 16 5.4 0.1 3.6 3 1 0 4 4 4 0 Anthranilate synthase component I, N terminal region Myb_DNA-bind_6 PF13921.1 KNE00344.1 - 4.3e-11 42.7 1.3 5.8e-10 39.1 0.1 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KNE00344.1 - 6e-07 29.4 1.7 4e-05 23.5 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain AvrPphF-ORF-2 PF09143.5 KNE00344.1 - 0.077 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 AvrPphF-ORF-2 PTH2 PF01981.11 KNE00345.1 - 4.1e-41 139.3 0.0 5.2e-41 138.9 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Apolipoprotein PF01442.13 KNE00347.1 - 3.3e-05 23.5 0.0 0.0002 20.9 0.0 1.9 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain DUF1798 PF08807.5 KNE00347.1 - 0.0077 15.9 3.3 1.7 8.3 0.2 2.4 1 1 1 2 2 2 2 Bacterial domain of unknown function (DUF1798) JmjN PF02375.12 KNE00347.1 - 0.096 12.2 0.1 0.8 9.2 0.0 2.5 3 0 0 3 3 3 0 jmjN domain SMI1_KNR4 PF09346.5 KNE00348.1 - 5.4e-39 133.1 0.0 1.9e-38 131.4 0.0 2.0 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) DIE2_ALG10 PF04922.7 KNE00349.1 - 9e-77 258.6 35.6 9e-77 258.6 24.7 2.4 2 1 0 2 2 2 1 DIE2/ALG10 family PQQ_3 PF13570.1 KNE00350.1 - 0.014 15.6 0.5 0.55 10.5 0.0 2.7 3 0 0 3 3 3 0 PQQ-like domain Ilm1 PF10311.4 KNE00352.1 - 0.016 14.7 0.0 0.018 14.5 0.0 1.1 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 DUF1057 PF06342.7 KNE00352.1 - 0.049 12.4 0.0 0.049 12.4 0.0 1.0 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) UPF1_Zn_bind PF09416.5 KNE00352.1 - 0.1 12.1 0.3 0.12 11.9 0.2 1.1 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) Gtr1_RagA PF04670.7 KNE00353.1 - 3.5e-69 232.4 0.3 4.7e-69 232.0 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DNA_pol_phi PF04931.8 KNE00353.1 - 0.049 11.4 0.1 0.083 10.6 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF815 PF05673.8 KNE00353.1 - 0.067 12.0 0.0 0.17 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 KNE00353.1 - 0.073 12.9 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain UNC45-central PF11701.3 KNE00353.1 - 1.1 8.9 3.8 7.4 6.2 0.3 2.6 2 1 1 3 3 3 0 Myosin-binding striated muscle assembly central adh_short_C2 PF13561.1 KNE00358.1 - 1.8e-26 93.4 0.1 2.2e-26 93.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KNE00358.1 - 1.5e-21 77.0 0.5 1.9e-21 76.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNE00358.1 - 2.8e-07 30.3 0.2 4e-07 29.8 0.1 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KNE00358.1 - 0.0021 17.7 0.2 0.0031 17.1 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 KNE00358.1 - 0.022 14.1 0.3 0.043 13.2 0.2 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 KNE00358.1 - 0.048 14.1 0.6 0.13 12.7 0.1 1.9 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DFP PF04127.10 KNE00358.1 - 0.11 12.1 0.1 0.32 10.6 0.1 1.7 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.3 KNE00358.1 - 0.11 12.3 0.1 0.27 11.0 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF4229 PF14012.1 KNE00360.1 - 0.074 12.9 2.8 0.089 12.7 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) MFS_1 PF07690.11 KNE00363.1 - 5e-42 143.8 28.6 5e-42 143.8 19.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FPN1 PF06963.7 KNE00363.1 - 0.0098 14.3 0.1 0.0098 14.3 0.1 2.0 2 0 0 2 2 2 1 Ferroportin1 (FPN1) DUF2335 PF10097.4 KNE00363.1 - 1.9 8.1 5.7 0.17 11.5 0.4 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2335) FA_hydroxylase PF04116.8 KNE00365.1 - 0.0018 18.6 7.7 0.0023 18.2 5.3 1.1 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily MMgT PF10270.4 KNE00366.1 - 4.8e-18 65.5 0.0 6.6e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Membrane magnesium transporter Glyco_hydro_15 PF00723.16 KNE00367.1 - 1.8e-56 191.5 0.0 2.5e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 SNF2_N PF00176.18 KNE00369.1 - 1.2e-67 227.8 4.0 1.2e-67 227.8 0.1 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KNE00369.1 - 6.4e-17 61.1 0.0 1.5e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KNE00369.1 - 4e-05 23.1 0.0 0.0001 21.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Pro_CA PF00484.14 KNE00373.1 - 1.6e-40 138.6 0.0 2.1e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Lysine_decarbox PF03641.9 KNE00375.1 - 1.6e-39 134.7 0.0 2e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase SNARE PF05739.14 KNE00378.1 - 1.5e-08 34.1 0.6 3.6e-08 32.9 0.4 1.7 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 KNE00378.1 - 0.00021 20.8 0.4 0.00026 20.5 0.3 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 PhoU PF01895.14 KNE00378.1 - 3.6 8.1 6.1 4.6 7.7 0.3 2.9 3 0 0 3 3 3 0 PhoU domain Vps55 PF04133.9 KNE00379.1 - 3.9e-40 136.3 3.9 4.5e-40 136.1 2.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF998 PF06197.8 KNE00379.1 - 0.011 15.0 2.8 0.37 10.0 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF998) SirB PF04247.7 KNE00379.1 - 0.018 14.7 0.5 0.54 9.9 0.0 2.2 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB MerC PF03203.9 KNE00379.1 - 0.16 12.3 1.5 0.45 10.8 0.1 2.0 2 0 0 2 2 2 0 MerC mercury resistance protein DUF981 PF06168.6 KNE00379.1 - 0.44 10.2 6.0 0.91 9.2 4.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF981) DUF1029 PF06269.7 KNE00379.1 - 8.2 6.5 11.2 0.89 9.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1029) DUF2873 PF11395.3 KNE00379.1 - 9.6 5.8 8.1 1.2 8.8 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2873) DUF4452 PF14618.1 KNE00381.1 - 0.023 14.5 0.1 0.029 14.1 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4452) tRNA-synt_1c PF00749.16 KNE00382.1 - 2.5e-101 338.5 0.0 3.1e-101 338.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain SMC_N PF02463.14 KNE00383.1 - 3.5e-23 82.0 6.6 7.2e-23 80.9 4.6 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KNE00383.1 - 1.6e-09 38.4 43.7 1.6e-09 38.4 30.3 6.0 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 KNE00383.1 - 0.00021 20.7 0.0 0.00045 19.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 KNE00383.1 - 0.0018 18.2 0.1 0.0018 18.2 0.0 3.5 3 2 0 3 3 3 2 AAA domain AAA PF00004.24 KNE00383.1 - 0.012 15.8 9.2 0.041 14.0 0.0 3.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KNE00383.1 - 0.042 14.6 0.2 0.042 14.6 0.1 4.6 3 2 0 3 3 3 0 AAA domain MobB PF03205.9 KNE00383.1 - 0.048 13.3 3.8 1.8 8.2 0.1 2.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KNE00383.1 - 0.079 12.3 0.5 0.39 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KNE00383.1 - 0.093 13.0 0.1 0.093 13.0 0.1 4.6 3 1 0 3 3 3 0 ABC transporter RNA_helicase PF00910.17 KNE00383.1 - 0.23 11.6 1.2 0.74 10.0 0.0 2.6 3 0 0 3 3 3 0 RNA helicase SLD3 PF08639.5 KNE00385.1 - 0.064 11.8 3.6 0.056 12.0 2.5 1.0 1 0 0 1 1 1 0 DNA replication regulator SLD3 DUF1168 PF06658.7 KNE00385.1 - 0.22 11.0 8.7 0.2 11.1 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) SR-25 PF10500.4 KNE00385.1 - 0.27 10.6 6.6 0.23 10.9 4.5 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CMS1 PF14617.1 KNE00385.1 - 0.96 8.4 4.3 0.87 8.6 3.0 1.0 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Peptidase_S49_N PF08496.5 KNE00385.1 - 0.97 9.2 4.9 0.92 9.2 3.4 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NST1 PF13945.1 KNE00385.1 - 1 9.4 6.3 0.91 9.5 4.4 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF1387 PF07139.6 KNE00385.1 - 7.4 6.0 8.3 6.3 6.3 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) eRF1_1 PF03463.10 KNE00387.1 - 8.8e-32 109.4 1.2 1.5e-31 108.7 0.8 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 KNE00387.1 - 8e-26 90.9 0.1 1.2e-25 90.3 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KNE00387.1 - 2.2e-22 79.4 0.4 1.2e-21 77.0 0.0 2.4 3 0 0 3 3 3 1 eRF1 domain 3 Methyltransf_15 PF09445.5 KNE00388.1 - 3.7e-45 153.4 0.0 5e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 KNE00388.1 - 3.7e-11 43.0 0.0 5.3e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNE00388.1 - 1e-10 41.4 0.0 1.7e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNE00388.1 - 1.6e-09 38.3 0.0 2.8e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNE00388.1 - 1.9e-08 34.5 0.0 4.6e-08 33.3 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNE00388.1 - 5e-06 26.9 0.0 1.5e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KNE00388.1 - 7.9e-06 25.5 0.0 1.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.1 KNE00388.1 - 1.1e-05 25.2 0.1 3e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain N6_Mtase PF02384.11 KNE00388.1 - 0.00033 19.8 0.0 0.00047 19.3 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_12 PF08242.7 KNE00388.1 - 0.00079 19.8 0.0 0.0028 18.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KNE00388.1 - 0.00085 18.7 0.0 0.003 16.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 KNE00388.1 - 0.00098 18.3 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KNE00388.1 - 0.0037 16.3 0.0 0.0058 15.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.10 KNE00388.1 - 0.005 16.2 0.0 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 tRNA_U5-meth_tr PF05958.6 KNE00388.1 - 0.0074 15.0 0.0 0.011 14.4 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Pox_MCEL PF03291.11 KNE00388.1 - 0.011 14.6 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme Methyltransf_4 PF02390.12 KNE00388.1 - 0.019 14.0 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DUF552 PF04472.7 KNE00388.1 - 0.092 12.6 0.0 0.27 11.1 0.0 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF552) tRNA_bind PF01588.15 KNE00389.1 - 2.2e-27 94.7 0.0 4.2e-27 93.8 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain MCLC PF05934.6 KNE00389.1 - 0.00057 18.3 1.8 0.00085 17.7 1.2 1.2 1 0 0 1 1 1 1 Mid-1-related chloride channel (MCLC) DUF2201_N PF13203.1 KNE00389.1 - 0.0019 17.4 6.7 0.0028 16.8 4.6 1.2 1 0 0 1 1 1 1 Putative metallopeptidase domain GST_C_3 PF14497.1 KNE00389.1 - 0.028 14.9 0.8 0.1 13.0 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain RR_TM4-6 PF06459.7 KNE00389.1 - 1.5 8.6 18.0 2.9 7.7 12.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med3 PF11593.3 KNE00389.1 - 7.2 5.7 10.1 3.7 6.7 5.4 1.6 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal GFO_IDH_MocA PF01408.17 KNE00390.1 - 1.2e-22 80.7 0.8 2.5e-22 79.6 0.2 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 KNE00390.1 - 0.00021 21.6 0.2 0.00038 20.8 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KNE00390.1 - 0.00024 21.4 0.1 0.00067 20.0 0.0 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 KNE00390.1 - 0.0034 17.6 0.1 0.0079 16.4 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KNE00390.1 - 0.069 12.1 0.0 0.14 11.0 0.0 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase ATPgrasp_Ter PF15632.1 KNE00390.1 - 0.13 10.9 0.3 0.18 10.4 0.2 1.2 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon PhyH PF05721.8 KNE00391.1 - 4.8e-15 56.1 0.0 1.1e-14 54.9 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.1 KNE00391.1 - 0.023 15.1 0.0 0.06 13.8 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.1 KNE00391.1 - 0.082 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase PAS PF00989.19 KNE00393.1 - 9.8e-06 25.3 0.0 2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 KNE00393.1 - 0.0014 18.9 0.0 0.0036 17.6 0.0 1.6 1 0 0 1 1 1 1 PAS domain Ser_hydrolase PF06821.8 KNE00393.1 - 0.049 13.2 0.4 0.091 12.3 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase Sugar_tr PF00083.19 KNE00394.1 - 3.7e-89 299.3 21.0 4.9e-89 298.9 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNE00394.1 - 3.8e-30 104.7 26.4 5.5e-22 77.9 5.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KNE00394.1 - 1.8e-06 26.4 15.0 7.5e-05 21.1 1.5 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Ribosomal_L18e PF00828.14 KNE00395.1 - 1.1e-33 116.3 0.6 1.4e-33 115.9 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 HD_3 PF13023.1 KNE00396.1 - 1.3e-38 132.2 0.0 1.8e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 KNE00396.1 - 7.5e-06 25.9 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 HD domain Evr1_Alr PF04777.8 KNE00399.1 - 1e-31 108.6 3.0 1.4e-31 108.2 2.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin_2 PF13098.1 KNE00400.1 - 0.00019 21.6 0.0 0.00053 20.1 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.15 KNE00400.1 - 0.00048 19.7 0.0 0.00062 19.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KNE00400.1 - 0.0072 16.4 0.1 0.12 12.4 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Mito_carr PF00153.22 KNE00401.1 - 2.4e-52 174.6 5.7 9.5e-17 60.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2215 PF10225.4 KNE00401.1 - 0.064 12.7 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Tox-GHH PF15636.1 KNE00404.1 - 0.03 13.9 0.3 0.034 13.7 0.2 1.1 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Pkinase PF00069.20 KNE00407.1 - 7.4e-44 149.8 0.0 1.4e-43 148.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE00407.1 - 4.4e-27 94.7 0.0 7.8e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase COX4 PF02936.9 KNE00409.1 - 7.7e-38 129.4 0.1 9.5e-38 129.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV SBP_bac_7 PF03480.8 KNE00409.1 - 0.11 11.5 0.2 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Sec3_C PF09763.4 KNE00410.1 - 3.2e-109 366.0 28.7 3.2e-109 366.0 19.9 1.4 2 0 0 2 2 2 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 KNE00410.1 - 2.9e-17 62.3 0.9 2.2e-16 59.4 0.0 2.7 3 0 0 3 3 3 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Baculo_PEP_C PF04513.7 KNE00410.1 - 0.053 13.3 4.6 0.18 11.6 0.2 3.8 2 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec66 PF09802.4 KNE00411.1 - 6.1e-65 218.1 2.2 7.6e-65 217.8 1.5 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Oxidored_q2 PF00420.19 KNE00411.1 - 0.046 13.3 0.1 0.067 12.7 0.1 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L HTH_12 PF08461.5 KNE00411.1 - 0.14 11.8 0.8 0.6 9.8 0.1 2.2 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain SieB PF14163.1 KNE00411.1 - 0.15 11.6 0.8 0.34 10.4 0.1 1.8 1 1 1 2 2 2 0 Superinfection exclusion protein B Arf PF00025.16 KNE00414.1 - 5e-38 130.0 0.1 1.8e-30 105.4 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 KNE00414.1 - 1.8e-11 43.4 0.1 4.2e-06 25.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KNE00414.1 - 1e-09 38.0 0.0 5.4e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 Ras family Miro PF08477.8 KNE00414.1 - 1.4e-08 35.2 0.0 1.3e-06 28.8 0.0 2.6 2 1 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 KNE00414.1 - 2.5e-08 33.3 0.0 2.3e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KNE00414.1 - 1.2e-05 24.8 0.0 2.4e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KNE00414.1 - 1.3e-05 24.5 0.0 0.00021 20.5 0.0 2.0 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KNE00414.1 - 0.00012 21.9 0.0 0.00044 20.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KNE00414.1 - 0.0072 16.4 0.0 0.04 14.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KNE00414.1 - 0.052 13.8 0.1 0.063 13.5 0.1 1.3 1 1 0 1 1 1 0 AAA domain BAR_2 PF10455.4 KNE00416.1 - 3.9e-84 281.9 14.7 5e-84 281.6 10.2 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking PRP38 PF03371.10 KNE00417.1 - 5.9e-52 175.7 0.3 6.6e-52 175.6 0.2 1.0 1 0 0 1 1 1 1 PRP38 family Nup84_Nup100 PF04121.8 KNE00419.1 - 3.6e-186 619.9 15.6 4.1e-186 619.7 10.8 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 DUF1039 PF06287.6 KNE00419.1 - 0.064 13.1 0.0 0.31 10.9 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1039) PCI PF01399.22 KNE00420.1 - 1.1e-16 61.0 0.2 1.1e-16 61.0 0.1 2.6 3 1 0 3 3 3 1 PCI domain DDRGK PF09756.4 KNE00420.1 - 0.013 14.9 0.4 0.013 14.9 0.3 2.5 2 1 1 3 3 3 0 DDRGK domain TPR_16 PF13432.1 KNE00420.1 - 0.028 15.0 3.1 29 5.4 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 KNE00420.1 - 0.11 12.5 5.1 4.5 7.4 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KNE00420.1 - 0.14 12.0 2.7 19 5.3 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KNE00420.1 - 0.28 10.8 4.4 16 5.3 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KNE00420.1 - 2 8.1 11.4 0.99 9.0 0.6 3.7 4 1 0 4 4 4 0 TPR repeat TPR_8 PF13181.1 KNE00420.1 - 2.5 8.0 15.9 6.4 6.8 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 KNE00420.1 - 4.3 7.4 11.5 46 4.2 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Methyltransf_23 PF13489.1 KNE00421.1 - 6.6e-16 58.4 0.0 1.2e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KNE00421.1 - 7.8e-13 48.0 0.0 1.2e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KNE00421.1 - 4e-12 46.4 0.0 8.8e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNE00421.1 - 6.6e-12 45.2 0.1 3.4e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNE00421.1 - 4e-10 40.0 0.0 7.2e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNE00421.1 - 5.7e-08 33.3 0.0 1.1e-07 32.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNE00421.1 - 2.1e-07 31.2 0.0 4.2e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNE00421.1 - 0.075 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Glyco_tran_WecB PF03808.8 KNE00421.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family MTS PF05175.9 KNE00421.1 - 0.18 11.1 0.0 0.34 10.2 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Synaptobrevin PF00957.16 KNE00421.1 - 0.19 11.3 2.1 0.97 9.0 0.0 2.5 2 1 0 2 2 2 0 Synaptobrevin SlyX PF04102.7 KNE00422.1 - 0.0013 19.0 2.3 0.0013 19.0 1.6 1.9 1 1 1 2 2 2 1 SlyX DivIC PF04977.10 KNE00422.1 - 0.0053 16.2 2.3 0.0053 16.2 1.6 1.9 2 0 0 2 2 2 1 Septum formation initiator DUF489 PF04356.7 KNE00422.1 - 0.036 13.6 0.7 0.041 13.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) FbpA PF05833.6 KNE00422.1 - 0.057 11.9 5.4 0.064 11.7 3.8 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) GTPase_Cys_C PF12631.2 KNE00422.1 - 0.16 12.3 0.8 0.44 10.9 0.2 1.9 1 1 1 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE TBPIP PF07106.8 KNE00422.1 - 0.4 10.2 6.9 0.47 9.9 4.8 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Microtub_assoc PF07989.6 KNE00422.1 - 0.41 10.5 5.8 0.77 9.6 3.6 1.9 1 1 0 1 1 1 0 Microtubule associated AKNA PF12443.3 KNE00422.1 - 0.51 10.3 3.2 0.82 9.7 0.8 2.0 1 1 1 2 2 2 0 AT-hook-containing transcription factor bZIP_1 PF00170.16 KNE00422.1 - 0.94 9.4 4.5 0.77 9.7 1.2 2.1 1 1 1 2 2 2 0 bZIP transcription factor DUF724 PF05266.9 KNE00422.1 - 1.1 8.8 5.9 1.3 8.5 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF904 PF06005.7 KNE00422.1 - 2.1 8.7 9.3 4 7.8 6.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF904) IncA PF04156.9 KNE00422.1 - 6.4 6.3 8.9 7.4 6.1 6.2 1.1 1 0 0 1 1 1 0 IncA protein RF-1 PF00472.15 KNE00423.1 - 8e-37 125.5 2.4 1.6e-36 124.5 1.6 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 KNE00423.1 - 1.6e-28 98.7 0.0 4.1e-28 97.3 0.0 1.7 1 0 0 1 1 1 1 PCRF domain RRM_5 PF13893.1 KNE00424.1 - 2.3e-11 43.3 0.0 3.3e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KNE00424.1 - 1.9e-09 37.0 0.0 2.7e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNE00424.1 - 3e-06 27.1 0.0 4.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) E3_UbLigase_EDD PF11547.3 KNE00424.1 - 0.051 13.0 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD NAD_binding_8 PF13450.1 KNE00425.1 - 5.9e-11 42.2 0.0 1.2e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KNE00425.1 - 2.8e-05 23.3 0.1 0.00022 20.3 0.0 2.3 3 0 0 3 3 3 1 Thi4 family Amino_oxidase PF01593.19 KNE00425.1 - 3.6e-05 23.0 0.0 4.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 KNE00425.1 - 0.00011 22.5 0.0 0.043 14.2 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KNE00425.1 - 0.00015 20.8 0.0 0.00035 19.6 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Mqo PF06039.10 KNE00425.1 - 0.0011 17.2 0.0 0.0087 14.2 0.0 2.0 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.1 KNE00425.1 - 0.0017 18.1 0.0 0.0039 16.9 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KNE00425.1 - 0.0074 16.3 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KNE00425.1 - 0.014 15.2 0.0 0.038 13.8 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Arrestin_C PF02752.17 KNE00426.1 - 2.2e-26 92.5 0.0 6e-26 91.1 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KNE00426.1 - 0.056 13.2 0.0 0.15 11.8 0.0 1.7 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain DAGK_cat PF00781.19 KNE00428.1 - 7.3e-23 80.4 0.1 1.2e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Thioredoxin PF00085.15 KNE00429.1 - 4.8e-16 58.3 0.0 5.9e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 KNE00429.1 - 8.9e-06 25.2 0.0 1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KNE00429.1 - 0.00014 22.0 0.3 0.00093 19.3 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KNE00429.1 - 0.00022 21.2 0.1 0.022 14.8 0.1 2.2 1 1 1 2 2 2 2 Thioredoxin-like Redoxin PF08534.5 KNE00429.1 - 0.066 12.7 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.16 KNE00429.1 - 0.083 12.5 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family DUF2284 PF10050.4 KNE00429.1 - 0.13 11.8 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) UBA_e1_thiolCys PF10585.4 KNE00430.1 - 0.0069 15.7 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Sugar_tr PF00083.19 KNE00431.1 - 9.4e-83 278.2 28.4 1.1e-82 277.9 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNE00431.1 - 1.8e-15 56.5 38.0 1.8e-15 56.5 26.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1700 PF08006.6 KNE00431.1 - 1.9 7.7 4.4 0.67 9.2 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) 2-Hacid_dh_C PF02826.14 KNE00432.1 - 1.3e-54 184.0 0.0 2e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KNE00432.1 - 1.9e-36 124.4 0.1 2.6e-36 124.0 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KNE00432.1 - 2.4e-06 27.4 0.2 6.6e-06 26.0 0.2 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 KNE00432.1 - 2e-05 24.5 0.1 3.8e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.20 KNE00432.1 - 0.0011 18.3 0.0 0.0034 16.8 0.0 1.8 1 0 0 1 1 1 1 ACT domain IlvN PF07991.7 KNE00432.1 - 0.0016 17.7 0.2 0.0038 16.6 0.0 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 KNE00432.1 - 0.013 15.2 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 KNE00432.1 - 0.023 15.0 0.0 0.063 13.5 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain Acetyltransf_1 PF00583.19 KNE00432.1 - 0.064 13.3 0.0 0.36 10.8 0.0 2.3 1 1 1 2 2 2 0 Acetyltransferase (GNAT) family UDPG_MGDP_dh_N PF03721.9 KNE00432.1 - 0.27 10.6 1.9 0.78 9.0 0.4 2.2 2 1 1 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain A_deaminase PF00962.17 KNE00433.1 - 1.5e-45 155.5 0.0 2.6e-45 154.8 0.0 1.3 1 1 0 1 1 1 1 Adenosine/AMP deaminase MFS_1 PF07690.11 KNE00434.1 - 5.9e-27 94.2 24.3 8.2e-27 93.8 16.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Kinesin PF00225.18 KNE00435.1 - 4.4e-100 334.6 0.0 4.4e-100 334.6 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain Pox_A_type_inc PF04508.7 KNE00435.1 - 8 6.5 9.2 2.6 8.0 2.5 3.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat TPT PF03151.11 KNE00437.1 - 2e-06 27.5 16.1 2e-06 27.5 11.2 4.7 4 2 1 5 5 5 2 Triose-phosphate Transporter family EmrE PF13536.1 KNE00437.1 - 0.00043 20.4 4.9 0.00043 20.4 3.4 3.0 3 1 0 3 3 3 2 Multidrug resistance efflux transporter EamA PF00892.15 KNE00437.1 - 0.00087 19.3 44.6 0.0015 18.6 4.7 3.2 3 1 1 4 4 4 2 EamA-like transporter family PX PF00787.19 KNE00438.1 - 9.5e-20 70.4 0.2 2.4e-19 69.1 0.1 1.8 1 0 0 1 1 1 1 PX domain DUF3445 PF11927.3 KNE00439.1 - 2.6e-76 256.3 0.0 3.3e-76 255.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) SpoU_methylase PF00588.14 KNE00440.1 - 8.8e-27 93.7 0.0 3.9e-25 88.3 0.0 2.5 2 0 0 2 2 2 2 SpoU rRNA Methylase family RNase_PH PF01138.16 KNE00441.1 - 8.2e-13 48.8 0.1 2.2e-12 47.4 0.1 1.7 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KNE00441.1 - 0.00031 20.6 0.0 0.0011 18.8 0.0 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Nup35_RRM PF05172.8 KNE00442.1 - 5.8e-25 86.9 0.0 1.2e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 KNE00442.1 - 1.2e-05 25.0 0.2 9.9e-05 22.0 0.1 2.2 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF2418 PF10332.4 KNE00443.1 - 1e-25 89.9 2.5 2.1e-25 88.8 1.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) ADIP PF11559.3 KNE00444.1 - 0.21 11.4 22.8 0.1 12.4 1.5 3.4 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.6 KNE00444.1 - 0.38 10.6 2.3 2.8 7.8 0.2 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) SlyX PF04102.7 KNE00444.1 - 0.84 10.0 12.9 0.79 10.1 0.8 4.1 3 1 1 4 4 4 0 SlyX DUF972 PF06156.8 KNE00444.1 - 2.3 8.6 17.5 0.43 10.9 1.3 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF972) TMF_DNA_bd PF12329.3 KNE00444.1 - 5.4 6.9 16.9 1.6 8.5 0.1 3.6 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Y_phosphatase PF00102.22 KNE00445.1 - 1.1e-56 191.7 0.6 1.6e-56 191.3 0.4 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 KNE00445.1 - 1.1e-08 35.4 0.0 2.7e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain DSPc PF00782.15 KNE00445.1 - 0.035 13.6 0.0 0.094 12.2 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF3802 PF12290.3 KNE00445.1 - 0.071 13.4 0.1 0.2 11.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3802) Renin_r PF07850.9 KNE00447.1 - 0.2 12.0 0.9 0.21 11.9 0.6 1.1 1 0 0 1 1 1 0 Renin receptor-like protein Prenyltrans PF00432.16 KNE00448.1 - 1.2e-43 146.2 11.5 1.5e-10 40.4 0.1 5.2 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KNE00448.1 - 5.3e-22 78.3 0.0 5.5e-14 52.5 0.0 3.2 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 KNE00448.1 - 6.1e-06 26.2 0.0 0.0053 16.7 0.0 3.2 1 1 2 3 3 3 2 Prenyltransferase-like UBX PF00789.15 KNE00449.1 - 2.9e-09 36.8 0.0 6.6e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 UBX domain DUF462 PF04315.7 KNE00449.1 - 0.035 13.4 0.7 0.059 12.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF462 SRP14 PF02290.10 KNE00451.1 - 2.1e-20 72.4 0.0 2.1e-20 72.4 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle 14kD protein MFS_1 PF07690.11 KNE00453.1 - 3.5e-25 88.4 19.0 6.8e-25 87.5 13.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.8 KNE00453.1 - 2.2e-18 66.4 5.5 2.2e-18 66.4 3.8 2.4 2 1 0 2 2 2 1 Nodulin-like MFS_3 PF05977.8 KNE00453.1 - 0.1 10.6 6.6 0.6 8.1 0.3 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector TarH PF02203.10 KNE00453.1 - 0.16 11.7 1.9 13 5.5 0.2 2.8 2 1 0 2 2 2 0 Tar ligand binding domain homologue Dynamin_N PF00350.18 KNE00454.1 - 5.1e-16 58.9 0.0 1.6e-15 57.3 0.0 1.9 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KNE00454.1 - 5.5e-09 36.0 0.1 3.4e-08 33.4 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KNE00454.1 - 1.3e-06 27.9 0.3 0.00048 19.6 0.3 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain PglZ PF08665.7 KNE00454.1 - 0.0074 15.9 3.3 0.0084 15.7 0.1 2.7 3 0 0 3 3 3 1 PglZ domain AAA_18 PF13238.1 KNE00454.1 - 0.011 15.9 0.0 0.11 12.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KNE00454.1 - 0.019 15.4 0.0 0.61 10.5 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 KNE00454.1 - 0.15 11.6 0.0 0.4 10.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ureidogly_hydro PF04115.7 KNE00455.1 - 1e-48 164.7 0.0 1.2e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase Adaptin_binding PF10199.4 KNE00456.1 - 4.9e-06 26.8 5.8 0.00019 21.7 3.2 2.4 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 AAA_18 PF13238.1 KNE00456.1 - 0.0064 16.7 0.2 0.021 15.1 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 KNE00456.1 - 0.015 16.0 0.1 0.16 12.7 0.1 2.3 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KNE00456.1 - 0.064 13.2 0.1 0.23 11.4 0.0 2.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase Sec15 PF04091.7 KNE00457.1 - 9.2e-89 297.8 3.8 9.2e-89 297.8 2.6 2.5 3 1 0 3 3 3 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.9 KNE00457.1 - 0.0059 16.2 6.6 0.022 14.4 4.6 2.0 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain LOH1CR12 PF10158.4 KNE00457.1 - 0.056 13.2 4.7 0.046 13.5 1.7 2.1 2 0 0 2 2 2 0 Tumour suppressor protein DUF948 PF06103.6 KNE00457.1 - 0.55 10.1 6.0 3.5 7.5 0.2 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) NuA4 PF09340.5 KNE00459.1 - 4.3e-26 90.3 2.6 5.8e-26 89.9 1.8 1.2 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Glyco_transf_8 PF01501.15 KNE00459.1 - 0.076 12.3 0.1 0.11 11.8 0.1 1.4 1 1 0 1 1 1 0 Glycosyl transferase family 8 TM1586_NiRdase PF14512.1 KNE00459.1 - 0.16 11.1 0.1 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 Putative TM nitroreductase MRP-L28 PF09812.4 KNE00460.1 - 2.5e-33 115.1 2.4 3.1e-33 114.8 1.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Pkinase PF00069.20 KNE00462.1 - 1.7e-73 246.9 0.0 2.4e-73 246.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE00462.1 - 4.5e-32 111.1 0.0 6.5e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KNE00462.1 - 1.1e-09 38.7 2.0 1.1e-09 38.7 1.4 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 KNE00462.1 - 0.00053 19.0 0.0 0.0012 17.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KNE00462.1 - 0.0049 15.9 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KNE00462.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 KNE00463.1 - 9.7e-72 241.2 0.6 2e-71 240.1 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE00463.1 - 5.8e-36 123.8 0.0 1.1e-35 122.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNE00463.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KNE00463.1 - 0.034 13.2 0.1 0.19 10.7 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 KNE00464.1 - 0.021 14.7 3.2 2.6 8.0 0.0 3.7 3 1 0 3 3 3 0 WD domain, G-beta repeat zf-rbx1 PF12678.2 KNE00464.1 - 0.093 12.8 4.5 0.092 12.8 1.6 2.1 1 1 1 2 2 2 0 RING-H2 zinc finger DZR PF12773.2 KNE00464.1 - 6.6 6.6 10.3 69 3.3 7.3 2.4 1 1 1 2 2 2 0 Double zinc ribbon Pkinase PF00069.20 KNE00465.1 - 4.1e-63 212.9 0.0 7.3e-63 212.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE00465.1 - 1.7e-36 125.6 0.0 3e-36 124.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 KNE00465.1 - 1.9e-27 94.8 19.4 3.7e-15 55.4 2.8 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 KNE00465.1 - 1.2e-17 63.3 40.8 3.8e-10 39.3 10.1 2.8 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 KNE00465.1 - 5.5e-12 46.0 1.6 5.5e-12 46.0 1.1 2.9 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 KNE00465.1 - 0.0015 17.5 0.1 0.0065 15.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Ras PF00071.17 KNE00466.1 - 2.4e-21 75.7 0.0 3.8e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNE00466.1 - 2.9e-12 47.1 0.1 7.6e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 KNE00466.1 - 0.0001 22.4 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_32 PF13654.1 KNE00466.1 - 0.00037 19.2 0.0 0.00058 18.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KNE00466.1 - 0.004 17.1 0.0 0.0075 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KNE00466.1 - 0.0043 16.2 0.0 0.0075 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 KNE00466.1 - 0.013 14.9 0.1 0.082 12.3 0.0 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Hpr_kinase_C PF07475.7 KNE00466.1 - 0.038 13.3 0.4 0.19 11.0 0.1 2.1 2 1 0 2 2 2 0 HPr Serine kinase C-terminal domain Septin PF00735.13 KNE00466.1 - 0.038 13.0 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 Septin NACHT PF05729.7 KNE00466.1 - 0.051 13.2 0.0 0.098 12.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.18 KNE00466.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_10 PF12846.2 KNE00466.1 - 0.069 12.5 0.0 0.18 11.1 0.0 1.6 1 1 1 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 KNE00466.1 - 0.077 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase KaiC PF06745.8 KNE00466.1 - 0.083 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.21 KNE00466.1 - 0.088 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain TraG-D_C PF12696.2 KNE00466.1 - 0.65 9.8 5.8 7.2 6.4 0.0 2.8 2 1 1 3 3 3 0 TraM recognition site of TraD and TraG CBF PF03914.12 KNE00467.1 - 2.6e-43 147.3 1.9 8.4e-43 145.6 0.2 2.6 2 0 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.6 KNE00467.1 - 0.0096 16.1 1.6 0.038 14.2 0.3 2.6 2 0 0 2 2 2 1 Nucleolar complex-associated protein Pkinase PF00069.20 KNE00468.1 - 5.9e-62 209.1 0.0 8e-62 208.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE00468.1 - 3.1e-34 118.2 0.0 4.1e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNE00468.1 - 6.1e-06 25.4 0.0 1.4e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like DIT1_PvcA PF05141.7 KNE00469.1 - 2.5e-89 299.2 0.0 3.6e-89 298.7 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein HNH_4 PF13395.1 KNE00469.1 - 0.098 12.3 0.1 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 HNH endonuclease UPF0047 PF01894.12 KNE00470.1 - 1.1e-41 141.4 0.0 1.3e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 PHD PF00628.24 KNE00471.1 - 3.6e-10 39.3 8.3 3.6e-10 39.3 5.8 2.0 2 0 0 2 2 2 1 PHD-finger PEPcase PF00311.12 KNE00471.1 - 0.089 10.6 1.2 0.12 10.1 0.8 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Peptidase_S49_N PF08496.5 KNE00471.1 - 0.21 11.3 6.0 0.44 10.3 4.1 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal WD40 PF00400.27 KNE00472.1 - 6.3e-24 82.9 6.2 0.0087 15.9 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KNE00472.1 - 3.8e-15 55.5 0.1 8.7e-15 54.3 0.1 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Cellulase-like PF12876.2 KNE00472.1 - 0.025 14.9 1.2 1.6 9.1 0.0 3.7 3 1 0 3 3 3 0 Sugar-binding cellulase-like Vps55 PF04133.9 KNE00473.1 - 6.5e-33 113.0 3.3 7.8e-33 112.7 2.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 UbiA PF01040.13 KNE00473.1 - 0.0012 18.1 6.3 0.038 13.1 0.1 2.0 2 0 0 2 2 2 2 UbiA prenyltransferase family DUF1206 PF06724.6 KNE00473.1 - 0.049 13.3 2.5 6.9 6.4 0.0 2.8 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1206) DUF1077 PF06417.7 KNE00474.1 - 2.8e-46 155.9 4.0 3.3e-46 155.6 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) THUMP PF02926.12 KNE00475.1 - 1.1e-23 83.6 0.8 1.8e-23 83.0 0.6 1.4 1 0 0 1 1 1 1 THUMP domain CD99L2 PF12301.3 KNE00475.1 - 0.058 13.0 1.3 0.066 12.8 0.1 1.7 2 0 0 2 2 2 0 CD99 antigen like protein 2 F-box-like PF12937.2 KNE00476.1 - 4e-06 26.4 0.1 9.6e-06 25.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KNE00476.1 - 1.9e-05 24.1 0.1 4.3e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 F-box domain Phage_pRha PF09669.5 KNE00476.1 - 0.026 14.8 2.2 0.19 12.0 1.1 2.6 2 1 1 3 3 3 0 Phage regulatory protein Rha (Phage_pRha) HSP70 PF00012.15 KNE00477.1 - 4e-224 745.0 8.0 4.7e-224 744.7 5.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KNE00477.1 - 1.7e-16 59.7 9.2 1.9e-16 59.5 1.1 2.7 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.11 KNE00477.1 - 6.8e-06 25.8 0.0 1.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 KNE00477.1 - 0.00087 18.6 0.5 0.3 10.3 0.0 3.1 4 1 1 5 5 5 2 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.1 KNE00477.1 - 0.027 14.2 9.9 1.8 8.3 0.7 4.8 3 2 0 3 3 3 0 Cell division protein FtsA Hydantoinase_A PF01968.13 KNE00477.1 - 0.058 12.4 4.2 4.3 6.3 0.2 3.2 3 1 0 3 3 3 0 Hydantoinase/oxoprolinase Proteasome PF00227.21 KNE00478.1 - 2.8e-48 163.7 0.0 3.7e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KNE00478.1 - 3e-11 42.4 0.1 3e-11 42.4 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Phage_CRI PF05144.9 KNE00478.1 - 0.037 13.1 0.1 0.06 12.4 0.1 1.2 1 0 0 1 1 1 0 Phage replication protein CRI Enolase_C PF00113.17 KNE00479.1 - 7.9e-155 514.2 0.1 1.3e-154 513.4 0.0 1.3 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KNE00479.1 - 5.9e-56 188.0 0.3 9.6e-56 187.3 0.2 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 KNE00479.1 - 0.11 12.4 0.1 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 Enolase C-terminal domain-like Aminotran_5 PF00266.14 KNE00480.1 - 2e-11 43.2 0.0 3.3e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V CBP4 PF07960.6 KNE00482.1 - 6.3e-48 161.6 0.7 7.2e-48 161.4 0.5 1.0 1 0 0 1 1 1 1 CBP4 DUF600 PF04634.7 KNE00482.1 - 0.034 14.1 0.1 0.07 13.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF600 Fungal_trans_2 PF11951.3 KNE00483.1 - 4.3e-12 45.3 0.5 7.4e-12 44.5 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNE00483.1 - 4e-08 33.0 8.4 6.4e-08 32.3 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ras PF00071.17 KNE00484.1 - 2.6e-50 169.9 0.0 3.2e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNE00484.1 - 7.3e-13 49.0 0.0 1e-12 48.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNE00484.1 - 1.4e-07 30.9 0.0 1.8e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family HMG_box_2 PF09011.5 KNE00485.1 - 6e-09 36.1 21.2 3.3e-06 27.3 1.7 4.5 3 2 0 3 3 3 2 HMG-box domain HMG_box PF00505.14 KNE00485.1 - 1.7e-06 28.2 18.8 0.0015 18.7 0.4 4.7 4 1 1 5 5 5 2 HMG (high mobility group) box DUF1074 PF06382.6 KNE00485.1 - 0.019 14.9 10.7 0.15 12.0 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1074) Med2 PF11214.3 KNE00485.1 - 0.22 11.5 6.6 0.56 10.2 4.6 1.6 1 0 0 1 1 1 0 Mediator complex subunit 2 Mnd1 PF03962.10 KNE00485.1 - 0.3 10.7 11.4 0.51 9.9 3.9 2.1 2 0 0 2 2 2 0 Mnd1 family V_ATPase_I PF01496.14 KNE00485.1 - 0.42 8.4 3.6 0.55 8.0 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2681 PF10883.3 KNE00485.1 - 0.86 9.8 8.0 2.3 8.4 5.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Syntaxin_2 PF14523.1 KNE00485.1 - 3.4 7.7 11.6 4.5 7.3 3.1 2.6 3 0 0 3 3 3 0 Syntaxin-like protein DUF2424 PF10340.4 KNE00486.1 - 4.1e-23 81.6 0.0 1.1e-22 80.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 KNE00486.1 - 2.4e-12 46.9 0.0 3.9e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNE00486.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.15 KNE00486.1 - 0.16 12.1 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Cpn60_TCP1 PF00118.19 KNE00488.1 - 2.4e-143 478.3 12.1 2.7e-143 478.1 8.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cyclin_N PF00134.18 KNE00489.1 - 4.3e-14 52.1 0.0 7.5e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KNE00489.1 - 1e-12 48.6 0.5 2.8e-12 47.2 0.0 1.9 2 0 0 2 2 2 1 Cyclin XhlA PF10779.4 KNE00490.1 - 0.061 13.2 3.0 0.1 12.5 2.1 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Na_Ca_ex PF01699.19 KNE00491.1 - 1.9e-47 160.3 31.0 9.8e-25 86.7 5.2 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SE PF08491.5 KNE00492.1 - 1.2e-117 391.6 0.0 1.5e-117 391.3 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 KNE00492.1 - 2.9e-10 39.6 0.1 2.8e-06 26.4 0.1 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KNE00492.1 - 1.1e-09 37.8 0.0 1.4e-08 34.1 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KNE00492.1 - 0.00038 20.4 0.1 0.00098 19.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KNE00492.1 - 0.001 19.1 0.1 0.0023 18.0 0.0 1.5 2 0 0 2 2 1 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 KNE00492.1 - 0.0011 18.1 0.1 0.052 12.6 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KNE00492.1 - 0.0012 17.8 0.5 0.0046 15.8 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 KNE00492.1 - 0.0015 18.1 0.1 0.0024 17.5 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 KNE00492.1 - 0.0017 18.2 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KNE00492.1 - 0.0035 17.6 0.4 0.011 16.0 0.1 2.1 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 KNE00492.1 - 0.0057 15.0 0.0 0.0085 14.4 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor Thi4 PF01946.12 KNE00492.1 - 0.013 14.6 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.11 KNE00492.1 - 0.025 14.0 0.1 0.056 12.8 0.0 1.6 2 0 0 2 2 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 KNE00492.1 - 0.039 12.8 0.1 0.094 11.5 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 KNE00492.1 - 0.045 12.2 0.0 0.063 11.7 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 KNE00492.1 - 0.047 13.4 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.16 KNE00492.1 - 0.052 13.3 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 1 0 ThiF family TrkA_N PF02254.13 KNE00492.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 KNE00492.1 - 0.098 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 KNE00492.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain W2 PF02020.13 KNE00493.1 - 5.4e-18 64.7 7.3 5.4e-18 64.7 5.1 2.4 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 KNE00493.1 - 1e-09 37.4 18.4 0.0018 17.6 2.3 4.1 1 1 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 KNE00493.1 - 4.1e-07 29.5 1.1 2.1e-06 27.2 0.0 2.6 3 1 1 4 4 4 1 Nucleotidyl transferase Hexapep_2 PF14602.1 KNE00493.1 - 4.3e-05 22.9 15.1 0.0013 18.2 2.0 3.5 1 1 2 3 3 3 3 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 KNE00493.1 - 0.051 13.6 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain Ctr PF04145.10 KNE00495.1 - 1.4e-19 70.6 21.7 7.4e-18 64.9 15.1 2.0 1 1 0 1 1 1 1 Ctr copper transporter family PGPGW PF09656.5 KNE00495.1 - 0.12 11.6 0.2 0.12 11.6 0.1 2.0 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) U3_assoc_6 PF08640.6 KNE00496.1 - 3e-29 100.5 4.1 4.3e-28 96.9 0.2 2.9 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 KNE00496.1 - 6.8e-05 23.1 0.6 0.0031 18.0 0.3 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KNE00496.1 - 0.00056 19.4 0.9 0.0012 18.4 0.4 1.7 1 1 0 1 1 1 1 TPR repeat TPR_16 PF13432.1 KNE00496.1 - 0.004 17.8 3.9 0.26 11.9 0.9 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 KNE00496.1 - 0.0042 17.1 0.8 3.1 8.2 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KNE00496.1 - 0.014 15.2 0.9 0.034 14.0 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat NRDE-2 PF08424.5 KNE00496.1 - 0.014 14.2 0.8 1.1 8.1 0.2 2.9 1 1 0 2 2 2 0 NRDE-2, necessary for RNA interference HAT PF02184.11 KNE00496.1 - 0.017 14.8 0.1 2.9 7.7 0.0 3.5 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat TPR_19 PF14559.1 KNE00496.1 - 0.069 13.4 0.8 0.9 9.9 0.6 2.6 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 KNE00496.1 - 0.074 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Suf PF05843.9 KNE00496.1 - 0.53 9.9 5.4 0.1 12.3 0.1 2.2 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) FNIP PF05725.7 KNE00497.1 - 0.07 13.0 0.5 0.2 11.6 0.3 1.8 1 0 0 1 1 1 0 FNIP Repeat SWIRM PF04433.12 KNE00498.1 - 3.7e-19 68.6 0.1 3.7e-19 68.6 0.0 2.5 3 0 0 3 3 3 1 SWIRM domain ZZ PF00569.12 KNE00498.1 - 4.5e-14 51.7 7.0 7.9e-14 50.9 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 KNE00498.1 - 3.9e-09 36.4 0.1 9.8e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KNE00498.1 - 1.5e-05 24.9 2.6 3e-05 24.0 0.0 2.6 3 1 0 3 3 3 1 Myb-like DNA-binding domain Baculo_IE-1 PF05290.6 KNE00498.1 - 0.46 10.2 4.1 1.2 8.8 2.8 1.7 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Ribosomal_S17e PF00833.13 KNE00499.1 - 4.8e-20 71.5 0.0 5.9e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 KNE00499.1 - 0.033 14.8 0.0 0.033 14.8 0.0 1.1 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal DAO PF01266.19 KNE00500.1 - 4.9e-54 183.5 0.0 1.7e-53 181.8 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KNE00500.1 - 2.1e-05 24.4 0.0 4.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Strep_67kDa_ant PF06100.6 KNE00500.1 - 0.0029 16.0 0.3 0.0053 15.1 0.1 1.4 2 0 0 2 2 2 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_9 PF13454.1 KNE00500.1 - 0.011 15.4 0.1 0.044 13.5 0.0 2.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KNE00500.1 - 0.026 14.5 0.0 0.77 9.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KNE00500.1 - 0.029 13.4 0.2 0.048 12.7 0.1 1.2 1 0 0 1 1 1 0 Thi4 family ATP-synt_S1 PF05827.7 KNE00502.1 - 4.6e-46 157.4 0.0 5.6e-46 157.1 0.0 1.0 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Peptidase_M18 PF02127.10 KNE00503.1 - 2.8e-158 526.9 0.0 3.2e-158 526.7 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 KNE00503.1 - 5.1e-06 25.4 0.0 0.017 13.9 0.0 2.7 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.23 KNE00503.1 - 0.025 14.0 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 HLH PF00010.21 KNE00504.1 - 6.1e-12 45.0 0.6 6.1e-12 45.0 0.4 2.9 3 1 0 3 3 3 1 Helix-loop-helix DNA-binding domain BPL_N PF09825.4 KNE00504.1 - 0.03 13.1 0.9 0.043 12.5 0.6 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal FliT PF05400.8 KNE00504.1 - 4.1 7.8 8.2 7.9 6.9 0.3 2.7 2 0 0 2 2 2 0 Flagellar protein FliT Mid2 PF04478.7 KNE00505.1 - 0.021 14.2 0.1 0.054 12.9 0.1 1.7 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor RIO1 PF01163.17 KNE00506.1 - 2.9e-72 242.0 2.4 2.9e-72 242.0 1.7 2.1 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KNE00506.1 - 8.5e-05 22.3 0.1 0.49 10.0 0.0 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KNE00506.1 - 0.012 14.6 0.1 0.13 11.2 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Y_phosphatase3 PF13350.1 KNE00506.1 - 3.5 7.8 8.3 5.4 7.2 4.8 2.1 1 1 1 2 2 2 0 Tyrosine phosphatase family DUF2201_N PF13203.1 KNE00506.1 - 5.1 6.1 12.3 7.6 5.6 8.5 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Kei1 PF08552.6 KNE00507.1 - 6.7e-12 45.4 0.1 7.7e-12 45.2 0.1 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 TLD PF07534.11 KNE00508.1 - 1.4e-26 93.1 0.8 5.8e-24 84.6 0.3 2.3 1 1 1 2 2 2 2 TLD NUC153 PF08159.7 KNE00509.1 - 3.8e-13 48.7 2.0 3.8e-13 48.7 1.4 2.9 3 0 0 3 3 3 1 NUC153 domain Y_phosphatase3 PF13350.1 KNE00510.1 - 4.6e-29 101.7 0.0 8.8e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Abhydrolase_5 PF12695.2 KNE00510.1 - 8.3e-12 45.0 0.0 1.4e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNE00510.1 - 5.3e-08 33.0 0.2 4.4e-07 30.0 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Y_phosphatase3C PF13348.1 KNE00510.1 - 4.2e-05 23.5 0.0 0.0001 22.3 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 KNE00510.1 - 9.5e-05 21.8 0.0 0.00025 20.4 0.0 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family EMP24_GP25L PF01105.19 KNE00512.1 - 3.9e-54 183.1 0.5 4.5e-54 182.9 0.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ThiF PF00899.16 KNE00513.1 - 1.2e-42 144.9 0.2 1.9e-42 144.3 0.1 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 KNE00513.1 - 5.4e-22 77.1 0.1 1e-21 76.2 0.1 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 KNE00513.1 - 1.2e-17 64.2 0.0 3.1e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 KNE00513.1 - 1e-05 25.6 0.0 2.8e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Herpes_BLRF2 PF05812.7 KNE00513.1 - 0.0037 17.0 0.2 0.0078 16.0 0.1 1.5 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein DAO PF01266.19 KNE00513.1 - 0.097 11.5 0.1 0.15 10.9 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Cep57_CLD_2 PF14197.1 KNE00513.1 - 2.1 8.3 7.2 0.24 11.3 1.9 1.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 WD40 PF00400.27 KNE00514.1 - 0.0076 16.0 0.3 4.5 7.3 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KNE00514.1 - 0.12 12.0 0.1 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Rad60-SLD PF11976.3 KNE00515.1 - 8.2e-17 60.6 0.4 1.9e-16 59.4 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Caleosin PF05042.8 KNE00515.1 - 0.34 10.4 2.5 1.6 8.2 0.0 2.4 3 0 0 3 3 3 0 Caleosin related protein Got1 PF04178.7 KNE00516.1 - 4e-34 117.2 20.3 5.8e-34 116.7 14.1 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family HIT PF01230.18 KNE00517.1 - 1.7e-24 86.1 0.1 2.2e-24 85.8 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KNE00517.1 - 2.2e-12 47.2 0.1 6.4e-12 45.7 0.0 1.6 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KNE00517.1 - 0.0026 17.4 1.2 0.005 16.4 0.8 1.7 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 MBOAT PF03062.14 KNE00519.1 - 6.7e-52 176.6 23.4 6.7e-52 176.6 16.2 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family PufQ PF05398.6 KNE00519.1 - 0.058 13.4 0.5 0.24 11.4 0.0 2.3 2 0 0 2 2 2 0 PufQ cytochrome subunit CTDII PF01556.13 KNE00520.1 - 1.4e-23 82.5 0.2 1.3e-20 73.0 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 KNE00520.1 - 3.9e-23 80.9 0.7 6.6e-23 80.2 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain RsgI_N PF12791.2 KNE00520.1 - 0.027 14.1 0.9 0.069 12.8 0.1 1.9 2 0 0 2 2 2 0 Anti-sigma factor N-terminus SET PF00856.23 KNE00522.1 - 0.0005 20.4 0.0 0.015 15.5 0.0 2.4 2 1 0 2 2 2 1 SET domain RFX_DNA_binding PF02257.10 KNE00524.1 - 8.6e-33 112.3 0.0 1.7e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.11 KNE00524.1 - 0.0053 16.9 0.0 0.038 14.2 0.0 2.4 2 1 1 3 3 3 1 Poxvirus D5 protein-like RNA_pol_Rpo13 PF12136.3 KNE00526.1 - 0.12 12.1 4.8 0.13 11.9 3.4 1.2 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain BSP_II PF05432.6 KNE00526.1 - 1.5 8.0 4.4 1.4 8.1 3.1 1.0 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Ribosomal_L30 PF00327.15 KNE00527.1 - 4.4e-12 45.3 0.1 9e-12 44.4 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DUF2036 PF09724.4 KNE00528.1 - 5.3e-60 203.2 0.7 6.1e-60 203.0 0.5 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Mito_carr PF00153.22 KNE00529.1 - 1.6e-32 111.0 0.7 1.6e-17 62.9 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Scaffolding_pro PF11418.3 KNE00530.1 - 0.12 12.6 0.7 0.12 12.6 0.5 1.0 1 0 0 1 1 1 0 Phi29 scaffolding protein Aminotran_5 PF00266.14 KNE00532.1 - 2.6e-91 306.1 0.0 3e-91 305.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KNE00532.1 - 4.1e-10 39.2 0.0 5.4e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.14 KNE00532.1 - 3.7e-05 22.3 0.1 5.3e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.12 KNE00532.1 - 0.00011 21.4 0.0 0.00023 20.3 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Iso_dh PF00180.15 KNE00533.1 - 5.4e-133 443.2 0.0 6.1e-133 443.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF3507 PF12015.3 KNE00534.1 - 1.2e-55 187.9 0.4 3.2e-55 186.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3507) RhoGEF PF00621.15 KNE00534.1 - 3.7e-08 33.4 1.8 3.7e-08 33.4 1.2 1.8 2 0 0 2 2 2 1 RhoGEF domain Peptidase_C15 PF01470.12 KNE00534.1 - 0.058 13.2 0.1 4.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Pyroglutamyl peptidase DUF2015 PF09435.5 KNE00535.1 - 1.9e-35 121.4 0.1 2.4e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) DUF3376 PF11856.3 KNE00535.1 - 0.013 14.8 0.4 0.021 14.2 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3376) WBP-1 PF11669.3 KNE00535.1 - 0.024 14.7 0.7 0.038 14.0 0.5 1.3 1 0 0 1 1 1 0 WW domain-binding protein 1 Ly49 PF08391.5 KNE00535.1 - 0.096 12.8 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Amnionless PF14828.1 KNE00535.1 - 0.096 11.1 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Amnionless Josephin PF02099.12 KNE00535.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Josephin RRM_1 PF00076.17 KNE00536.1 - 3.7e-57 189.8 0.4 1.2e-21 76.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNE00536.1 - 4.8e-42 141.7 0.1 7.1e-14 51.5 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNE00536.1 - 5.2e-20 71.0 0.0 3.2e-07 30.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KNE00536.1 - 1.3e-07 31.3 0.8 0.25 11.1 0.0 3.5 3 1 0 3 3 3 3 Limkain b1 DUF1325 PF07039.6 KNE00537.1 - 3.6e-32 110.7 0.0 5.2e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF4537 PF15057.1 KNE00537.1 - 0.0036 17.0 0.0 0.008 15.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) TBPIP PF07106.8 KNE00537.1 - 0.0092 15.5 1.8 0.014 14.9 1.3 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) YbaB_DNA_bd PF02575.11 KNE00537.1 - 0.27 11.1 2.3 0.83 9.5 0.1 2.2 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family TPT PF03151.11 KNE00538.1 - 0.042 13.4 5.0 0.21 11.2 2.4 2.5 1 1 0 1 1 1 0 Triose-phosphate Transporter family DctQ PF04290.7 KNE00538.1 - 0.18 11.5 7.6 0.058 13.1 2.6 2.2 2 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF2663 PF10864.3 KNE00538.1 - 3.1 8.0 7.6 0.31 11.2 0.8 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2663) YchF-GTPase_C PF06071.8 KNE00539.1 - 3.8e-29 100.2 0.1 6.9e-29 99.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KNE00539.1 - 9.7e-14 51.3 0.0 2.4e-13 50.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 KNE00539.1 - 2.6e-06 27.1 0.0 8.3e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 TGS domain FeoB_N PF02421.13 KNE00539.1 - 0.0019 17.4 0.0 0.008 15.4 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B PLDc_2 PF13091.1 KNE00541.1 - 1.9e-16 59.9 0.1 1.5e-07 31.2 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KNE00541.1 - 1.5e-06 27.7 0.4 0.077 12.8 0.1 3.2 2 1 0 2 2 2 2 Phospholipase D Active site motif zf-C4_Topoisom PF01396.14 KNE00542.1 - 0.16 11.4 0.1 0.45 10.0 0.1 1.6 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger DUF3533 PF12051.3 KNE00543.1 - 2.7e-132 441.1 19.2 3.4e-132 440.8 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Ribosomal_L27 PF01016.14 KNE00545.1 - 6.7e-31 105.9 0.0 1.3e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein Peptidase_S46 PF10459.4 KNE00545.1 - 1.1 7.5 9.3 1.7 6.9 6.4 1.3 1 0 0 1 1 1 0 Peptidase S46 Peptidase_M20 PF01546.23 KNE00546.1 - 5e-24 84.8 0.0 9.5e-24 83.9 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KNE00546.1 - 3.8e-11 42.7 0.0 6.9e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KNE00546.1 - 0.036 13.8 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 RNA_pol_N PF01194.12 KNE00547.1 - 1.4e-29 101.8 0.7 1.6e-29 101.6 0.5 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 KNE00547.1 - 0.014 15.4 0.3 0.018 15.1 0.2 1.2 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Slx4 PF09494.5 KNE00547.1 - 0.087 12.5 0.3 0.55 10.0 0.1 1.9 1 1 1 2 2 2 0 Slx4 endonuclease WD40 PF00400.27 KNE00548.1 - 0.00095 18.9 0.8 0.19 11.6 0.0 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat Dynamin_N PF00350.18 KNE00549.1 - 1.2e-40 139.1 0.0 4.6e-40 137.1 0.0 2.1 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KNE00549.1 - 0.00012 20.9 4.5 0.0048 15.7 0.6 2.9 2 1 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 KNE00549.1 - 0.00091 19.1 0.0 0.0037 17.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KNE00549.1 - 0.001 19.5 0.0 0.0028 18.1 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 KNE00549.1 - 0.0029 17.6 0.7 0.02 14.9 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain DAGK_prokar PF01219.14 KNE00549.1 - 0.066 12.8 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic diacylglycerol kinase AAA_21 PF13304.1 KNE00549.1 - 0.18 11.7 6.7 0.27 11.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 KNE00549.1 - 0.76 10.0 0.0 0.76 10.0 0.0 4.1 2 1 1 3 3 3 0 AAA domain Lectin_N PF03954.9 KNE00550.1 - 0.014 14.7 0.5 0.018 14.4 0.4 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain RHINO PF15319.1 KNE00556.1 - 0.031 14.0 0.1 0.038 13.8 0.1 1.1 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein Ribosomal_60s PF00428.14 KNE00557.1 - 1.1e-23 83.4 14.4 1.5e-23 83.0 10.0 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Rhomboid PF01694.17 KNE00558.1 - 5.1e-23 81.7 16.1 5.1e-23 81.7 11.2 1.6 2 0 0 2 2 2 1 Rhomboid family Sec23_trunk PF04811.10 KNE00560.1 - 5.9e-28 97.8 0.1 9.3e-19 67.7 0.0 2.4 1 1 1 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KNE00560.1 - 1.8e-18 65.8 0.0 3.5e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KNE00560.1 - 0.00014 22.3 0.1 0.025 15.0 0.0 3.4 3 1 0 3 3 3 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KNE00560.1 - 0.00023 20.6 0.7 0.00042 19.8 0.5 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger zf-ribbon_3 PF13248.1 KNE00560.1 - 0.018 14.2 2.3 0.065 12.4 1.6 2.0 1 0 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 KNE00560.1 - 0.025 14.5 2.4 0.037 13.9 0.6 2.1 2 0 0 2 2 2 0 Zinc ribbon domain RFC1 PF08519.7 KNE00560.1 - 0.046 13.4 0.2 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain A2L_zn_ribbon PF08792.5 KNE00560.1 - 0.083 12.3 1.0 0.29 10.6 0.7 1.9 1 0 0 1 1 1 0 A2L zinc ribbon domain DUF1749 PF08538.5 KNE00561.1 - 8.6e-89 297.4 0.0 1e-88 297.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KNE00561.1 - 9.1e-12 45.3 0.0 1.2e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNE00561.1 - 1.9e-08 34.2 0.0 6.8e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNE00561.1 - 0.00031 20.3 0.1 0.055 13.0 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.7 KNE00561.1 - 0.0028 17.0 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) FSH1 PF03959.8 KNE00561.1 - 0.0045 16.4 0.0 0.0086 15.5 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF2305 PF10230.4 KNE00561.1 - 0.0061 16.0 0.0 0.023 14.0 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) DLH PF01738.13 KNE00561.1 - 0.0065 15.7 0.0 0.064 12.5 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family LCAT PF02450.10 KNE00561.1 - 0.035 13.0 0.0 0.083 11.8 0.0 1.6 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase CASP_C PF08172.7 KNE00562.1 - 6.5e-71 238.2 9.8 6.5e-71 238.2 6.8 4.1 3 1 0 3 3 3 2 CASP C terminal DUF972 PF06156.8 KNE00562.1 - 0.002 18.4 4.8 0.002 18.4 3.3 6.9 5 2 1 6 6 6 3 Protein of unknown function (DUF972) ubiquitin PF00240.18 KNE00562.1 - 0.1 12.0 7.4 0.39 10.1 0.4 3.7 3 0 0 3 3 3 0 Ubiquitin family Reo_sigmaC PF04582.7 KNE00562.1 - 0.5 9.4 27.6 0.81 8.8 2.8 3.5 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Hemerythrin PF01814.18 KNE00562.1 - 2.9 8.0 17.2 0.35 11.0 0.2 4.4 4 0 0 4 4 4 0 Hemerythrin HHE cation binding domain S4 PF01479.20 KNE00563.1 - 7.4e-12 44.5 2.0 7.6e-12 44.4 0.3 1.8 2 0 0 2 2 2 1 S4 domain ATP_bind_4 PF01902.12 KNE00565.1 - 3.3e-41 141.0 0.0 5.8e-40 136.9 0.0 2.7 2 1 0 2 2 2 1 ATP-binding region Ribonuc_L-PSP PF01042.16 KNE00565.1 - 9.3e-22 77.0 0.2 4e-12 45.9 0.0 2.3 2 0 0 2 2 2 2 Endoribonuclease L-PSP ALS_ss_C PF10369.4 KNE00565.1 - 0.079 12.7 0.5 10 5.9 0.1 2.6 2 0 0 2 2 2 0 Small subunit of acetolactate synthase PPR_2 PF13041.1 KNE00566.1 - 1e-12 47.7 2.6 0.0019 18.1 0.0 5.2 4 2 2 6 6 6 3 PPR repeat family PPR_3 PF13812.1 KNE00566.1 - 6.9e-11 41.5 5.4 9.5e-05 22.3 0.0 7.7 10 0 0 10 10 10 2 Pentatricopeptide repeat domain PPR PF01535.15 KNE00566.1 - 7e-11 41.3 0.1 0.017 15.0 0.0 4.8 4 0 0 4 4 4 3 PPR repeat DUF2767 PF10965.3 KNE00566.1 - 0.022 14.5 0.4 0.47 10.3 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2767) tRNA-synt_1 PF00133.17 KNE00567.1 - 6.1e-54 183.0 0.0 3.8e-31 107.7 0.1 6.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 KNE00567.1 - 2.2e-43 147.7 0.0 4.2e-43 146.8 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 KNE00567.1 - 3.2e-29 101.8 0.1 5.4e-21 74.6 0.0 4.1 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KNE00567.1 - 5.5e-11 42.4 0.0 1.3e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KNE00567.1 - 0.00023 20.4 0.0 0.31 10.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 KNE00567.1 - 0.0093 14.8 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) RIC1 PF07064.8 KNE00568.1 - 0.0039 16.6 0.0 0.007 15.8 0.0 1.4 1 0 0 1 1 1 1 RIC1 WD40 PF00400.27 KNE00569.1 - 1.7e-10 40.3 4.1 4.1e-08 32.7 0.0 4.5 5 0 0 5 5 5 1 WD domain, G-beta repeat Lactonase PF10282.4 KNE00569.1 - 0.049 12.7 0.0 1.3 8.0 0.0 2.2 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller Herpes_UL17 PF04559.7 KNE00570.1 - 0.3 9.6 6.9 0.45 9.0 3.3 2.1 2 0 0 2 2 2 0 Herpesvirus UL17 protein HAD_2 PF13419.1 KNE00570.1 - 0.38 10.9 2.9 1.5 9.0 0.4 2.9 2 2 0 2 2 2 0 Haloacid dehalogenase-like hydrolase IncA PF04156.9 KNE00570.1 - 3 7.4 49.7 11 5.5 7.2 4.3 1 1 2 3 3 3 0 IncA protein DUF904 PF06005.7 KNE00570.1 - 6.1 7.2 40.2 0.19 12.0 2.3 5.5 4 1 2 6 6 6 0 Protein of unknown function (DUF904) DUF3393 PF11873.3 KNE00572.1 - 0.0051 16.3 0.8 0.0096 15.4 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3393) DUF2424 PF10340.4 KNE00573.1 - 3.9e-56 190.2 1.1 4.6e-56 190.0 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 KNE00573.1 - 2.5e-18 66.4 0.0 3.3e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNE00573.1 - 0.0027 17.4 0.0 0.0035 17.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 KNE00573.1 - 0.067 12.5 0.0 12 5.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.16 KNE00573.1 - 0.069 12.3 0.0 0.24 10.5 0.0 1.8 3 0 0 3 3 3 0 Prolyl oligopeptidase family zf-CCHC PF00098.18 KNE00574.1 - 4.6e-06 26.3 1.0 7.5e-06 25.6 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle KH_1 PF00013.24 KNE00574.1 - 4e-05 23.1 0.0 8.2e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KNE00574.1 - 5.7e-05 22.6 0.0 0.00022 20.8 0.0 2.0 1 0 0 1 1 1 1 KH domain eIF3g PF12353.3 KNE00574.1 - 0.14 12.0 0.1 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Methyltransf_26 PF13659.1 KNE00575.1 - 4.5e-15 55.7 0.0 6.5e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KNE00575.1 - 4.5e-10 39.1 0.0 6.5e-10 38.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 KNE00575.1 - 4.1e-05 23.2 0.0 6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNE00575.1 - 6.6e-05 23.4 0.0 0.00013 22.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNE00575.1 - 0.0003 21.1 0.0 0.02 15.3 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_16 PF10294.4 KNE00575.1 - 0.003 17.0 0.0 0.0041 16.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.7 KNE00575.1 - 0.033 14.6 0.0 0.11 12.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DUF938 PF06080.7 KNE00575.1 - 0.046 13.2 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_25 PF13649.1 KNE00575.1 - 0.065 13.5 0.0 0.096 13.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 KNE00575.1 - 0.066 12.7 0.0 0.094 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RNA_pol_Rpb2_6 PF00562.23 KNE00576.1 - 2.7e-112 375.3 0.0 3.9e-112 374.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KNE00576.1 - 1.6e-40 138.2 0.0 2.6e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KNE00576.1 - 4.8e-28 97.8 0.0 9.4e-28 96.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 KNE00576.1 - 5.2e-25 86.9 0.0 2.2e-24 84.9 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 KNE00576.1 - 1.2e-23 82.7 0.0 2.5e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 KNE00576.1 - 1.1e-15 57.6 0.0 3.5e-15 56.0 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 KNE00576.1 - 2.2e-05 24.3 0.2 5.4e-05 23.0 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 FUSC_2 PF13515.1 KNE00577.1 - 1.7e-31 108.7 6.2 1.7e-31 108.7 4.3 2.7 2 0 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 KNE00577.1 - 9.8e-10 38.4 2.6 6.2e-09 35.7 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC PF04632.7 KNE00577.1 - 1.2e-05 23.9 4.6 0.0001 20.9 2.5 2.5 2 1 0 2 2 2 1 Fusaric acid resistance protein family ALMT PF11744.3 KNE00577.1 - 0.00042 19.0 6.3 0.00042 19.0 4.4 2.8 2 2 0 2 2 2 1 Aluminium activated malate transporter LAGLIDADG_WhiA PF14527.1 KNE00577.1 - 0.046 13.5 0.2 0.26 11.1 0.1 2.2 2 0 0 2 2 2 0 WhiA LAGLIDADG-like domain Peptidase_S49_N PF08496.5 KNE00579.1 - 0.67 9.7 5.4 0.63 9.8 3.8 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ETRAMP PF09716.5 KNE00579.1 - 0.92 9.5 8.7 1.1 9.2 6.0 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) AgrB PF04647.10 KNE00579.1 - 7.1 5.6 5.7 8 5.4 4.0 1.0 1 0 0 1 1 1 0 Accessory gene regulator B Protocadherin PF08374.6 KNE00579.1 - 8 6.0 8.0 7.5 6.1 5.6 1.0 1 0 0 1 1 1 0 Protocadherin OB_NTP_bind PF07717.11 KNE00580.1 - 3.4e-26 91.3 0.0 7.2e-26 90.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KNE00580.1 - 1.6e-23 82.6 0.1 3.3e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KNE00580.1 - 8.1e-13 48.0 0.0 2.5e-12 46.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KNE00580.1 - 1.8e-05 24.3 0.2 3.9e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KNE00580.1 - 5.7e-05 23.2 0.1 0.00032 20.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 KNE00580.1 - 0.00017 21.1 0.1 0.0004 19.9 0.0 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 KNE00580.1 - 0.0039 17.2 0.0 0.026 14.5 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 KNE00580.1 - 0.01 14.7 0.0 0.02 13.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.17 KNE00580.1 - 0.039 12.8 0.0 0.18 10.6 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.1 KNE00580.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 KNE00580.1 - 0.14 11.9 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_29 PF13555.1 KNE00580.1 - 0.2 11.1 0.0 0.49 9.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arf PF00025.16 KNE00581.1 - 6.8e-66 220.8 0.1 7.5e-66 220.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KNE00581.1 - 1.3e-13 50.6 0.0 1.5e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KNE00581.1 - 2e-12 46.5 2.1 9.9e-10 37.6 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KNE00581.1 - 5e-11 42.1 0.0 5.7e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KNE00581.1 - 8.4e-11 41.4 0.0 1e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KNE00581.1 - 1.7e-08 34.9 0.0 2.4e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KNE00581.1 - 1.2e-07 31.7 0.0 1.6e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KNE00581.1 - 0.00056 19.3 0.3 0.0042 16.5 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KNE00581.1 - 0.024 13.9 0.7 0.34 10.1 0.5 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B Rib_5-P_isom_A PF06026.9 KNE00582.1 - 2.3e-56 189.7 0.0 2.9e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 KNE00582.1 - 0.032 13.8 0.0 2.2 7.8 0.0 2.3 1 1 1 2 2 2 0 DeoR C terminal sensor domain Ribosomal_S7e PF01251.13 KNE00584.1 - 8.8e-80 266.6 0.8 1e-79 266.4 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e SH3_1 PF00018.23 KNE00585.1 - 1.1e-24 85.5 0.5 2.4e-12 46.0 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KNE00585.1 - 4.9e-23 80.4 2.4 1.4e-12 47.0 0.0 3.2 3 0 0 3 3 3 2 Variant SH3 domain FCH PF00611.18 KNE00585.1 - 7.6e-22 77.3 0.2 7.6e-22 77.3 0.1 3.5 2 2 1 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.12 KNE00585.1 - 4e-13 48.6 0.0 2.3e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain DUF3166 PF11365.3 KNE00585.1 - 0.33 11.4 7.3 7.5 7.0 0.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3166) Serine_rich PF08824.5 KNE00587.1 - 0.12 12.0 0.1 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Serine rich protein interaction domain DUF3437 PF11919.3 KNE00587.1 - 0.15 11.7 0.2 0.15 11.7 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) DUF2183 PF09949.4 KNE00588.1 - 6.7e-35 119.0 0.0 1.6e-34 117.8 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) NmrA PF05368.8 KNE00588.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family zf-CCCH PF00642.19 KNE00589.1 - 2.8e-05 23.6 0.4 2.8e-05 23.6 0.3 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MOR2-PAG1_N PF14222.1 KNE00590.1 - 1.6e-136 456.2 2.4 7.4e-71 239.4 0.9 2.9 1 1 1 2 2 2 2 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 KNE00590.1 - 5.8e-92 308.1 0.4 5.8e-92 308.1 0.3 2.7 4 0 0 4 4 4 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 KNE00590.1 - 1.6e-21 75.7 16.5 4.3e-08 31.2 3.4 5.0 3 2 0 3 3 3 3 Cell morphogenesis central region MMS19_N PF14500.1 KNE00591.1 - 1.9e-82 276.4 6.3 1.9e-82 276.4 4.4 2.4 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 KNE00591.1 - 7.8e-77 258.7 6.4 7.8e-77 258.7 4.4 5.2 4 2 2 6 6 6 1 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 KNE00591.1 - 1.3e-05 25.3 1.2 0.47 10.7 0.0 4.6 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.17 KNE00591.1 - 0.0063 16.5 0.5 33 4.9 0.0 5.1 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.1 KNE00591.1 - 1.9 9.1 8.5 1.1e+02 3.4 0.0 5.8 7 0 0 7 7 7 0 HEAT-like repeat SpoIISA_toxin PF14171.1 KNE00592.1 - 0.01 15.0 2.0 0.013 14.7 1.4 1.1 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DUF4639 PF15479.1 KNE00592.1 - 0.038 12.6 0.4 0.044 12.4 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) DUF305 PF03713.8 KNE00592.1 - 0.24 11.2 1.3 2.5 7.9 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF305) DUF648 PF04890.8 KNE00592.1 - 0.53 9.3 5.5 0.64 9.1 3.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF648) SCP2 PF02036.12 KNE00593.1 - 1e-22 80.3 2.5 1.2e-22 80.1 1.7 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 KNE00593.1 - 1.1e-05 25.4 0.4 1.3e-05 25.1 0.3 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal WD40 PF00400.27 KNE00594.1 - 9.4e-10 38.0 0.0 0.044 13.6 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF3312 PF11768.3 KNE00594.1 - 0.0081 14.4 0.0 2.6 6.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3312) BBS2_Mid PF14783.1 KNE00594.1 - 0.089 12.5 0.1 1.5 8.6 0.0 2.9 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 KNE00594.1 - 0.14 11.6 0.0 0.81 9.0 0.0 2.5 1 1 0 1 1 1 0 PQQ-like domain PQQ_3 PF13570.1 KNE00594.1 - 0.15 12.3 0.0 1.1e+02 3.2 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain AAA_13 PF13166.1 KNE00595.1 - 0.097 11.1 4.1 0.13 10.7 2.8 1.1 1 0 0 1 1 1 0 AAA domain Seryl_tRNA_N PF02403.17 KNE00595.1 - 0.15 12.0 2.1 1.2 9.1 0.0 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DNA_topoisoIV PF00521.15 KNE00595.1 - 0.24 10.1 2.4 0.29 9.9 1.7 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A P4Ha_N PF08336.6 KNE00595.1 - 0.29 10.9 3.9 0.21 11.4 0.4 2.2 1 1 1 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region SlyX PF04102.7 KNE00595.1 - 3 8.2 7.8 16 5.9 1.0 3.2 2 1 1 3 3 3 0 SlyX Syntaxin-6_N PF09177.6 KNE00595.1 - 5.4 7.4 6.2 19 5.7 0.6 2.9 1 1 2 3 3 3 0 Syntaxin 6, N-terminal E1-E2_ATPase PF00122.15 KNE00596.1 - 7.7e-65 218.1 1.7 2.4e-64 216.5 1.2 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KNE00596.1 - 9.7e-45 152.3 6.8 9.7e-45 152.3 4.7 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KNE00596.1 - 1.1e-23 84.8 0.0 1.3e-22 81.2 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KNE00596.1 - 1.2e-16 60.4 0.0 2.7e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KNE00596.1 - 1.2e-12 48.4 0.0 3.9e-12 46.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KNE00596.1 - 1.5e-12 46.8 0.1 1.2e-11 43.8 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KNE00596.1 - 0.00071 19.2 0.3 0.0047 16.5 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cys_Met_Meta_PP PF01053.15 KNE00598.1 - 4.7e-139 462.9 0.1 5.4e-139 462.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KNE00598.1 - 4.1e-05 22.7 0.0 0.00046 19.3 0.0 2.2 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.6 KNE00598.1 - 0.00038 18.8 0.0 0.00057 18.2 0.0 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.16 KNE00598.1 - 0.00076 18.5 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cytochrom_C1 PF02167.10 KNE00599.1 - 2.5e-82 275.7 0.0 3e-82 275.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 KNE00599.1 - 0.0024 18.0 0.0 0.0052 16.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 KNE00599.1 - 0.031 15.0 0.6 0.087 13.6 0.2 2.0 2 1 0 2 2 2 0 Cytochrome c Sugar_tr PF00083.19 KNE00601.1 - 1.1e-109 367.0 29.2 1.2e-109 366.8 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNE00601.1 - 2.6e-27 95.4 35.5 1.1e-24 86.7 20.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 KNE00603.1 - 2.3e-64 217.0 0.0 2.9e-64 216.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE00603.1 - 1.1e-30 106.6 0.0 1.5e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KNE00603.1 - 0.01 14.8 0.2 0.044 12.8 0.1 2.0 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KNE00603.1 - 0.076 11.8 0.2 0.2 10.4 0.1 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 Kinase-like PF14531.1 KNE00603.1 - 0.12 11.3 0.0 0.68 8.8 0.0 2.0 2 0 0 2 2 2 0 Kinase-like FTR1 PF03239.9 KNE00604.1 - 7.8e-82 274.6 10.2 9.1e-82 274.4 7.1 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family FA_desaturase PF00487.19 KNE00604.1 - 0.0011 18.4 5.2 1.2 8.5 0.4 3.0 2 1 1 3 3 3 2 Fatty acid desaturase DUF3382 PF11862.3 KNE00604.1 - 0.014 15.3 4.0 0.18 11.7 0.4 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3382) Acetate_kinase PF00871.12 KNE00604.1 - 0.079 11.4 0.1 0.11 10.9 0.1 1.1 1 0 0 1 1 1 0 Acetokinase family BCLP PF12304.3 KNE00604.1 - 0.19 11.1 5.8 0.091 12.1 1.9 2.0 2 0 0 2 2 2 0 Beta-casein like protein DUF4229 PF14012.1 KNE00604.1 - 0.87 9.5 13.2 0.75 9.7 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF4229) UPF0104 PF03706.8 KNE00604.1 - 9 5.4 19.4 4.9 6.3 2.3 3.0 2 1 2 4 4 4 0 Uncharacterised protein family (UPF0104) ParBc PF02195.13 KNE00605.1 - 6.9e-12 45.3 0.0 8.5e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain NAD_binding_6 PF08030.7 KNE00606.1 - 8.8e-20 71.1 0.0 1.8e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KNE00606.1 - 4.8e-18 64.9 0.0 4.9e-17 61.7 0.0 2.3 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 KNE00606.1 - 2.5e-13 50.2 15.6 2.5e-13 50.2 10.8 2.4 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NfeD PF01957.13 KNE00606.1 - 9.6 6.3 7.8 43 4.2 0.1 2.6 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Suf PF05843.9 KNE00607.1 - 9.1e-14 51.8 22.2 4.4e-08 33.1 0.5 6.5 4 4 1 5 5 5 3 Suppressor of forked protein (Suf) TPR_14 PF13428.1 KNE00607.1 - 1.1e-10 41.1 6.1 8.6 7.3 0.0 9.2 7 2 4 11 11 11 3 Tetratricopeptide repeat HBS1_N PF08938.5 KNE00607.1 - 6.1e-05 23.0 0.1 1.2 9.2 0.1 3.6 3 0 0 3 3 3 1 HBS1 N-terminus TPR_16 PF13432.1 KNE00607.1 - 0.00011 22.7 4.9 1.9 9.2 0.0 6.6 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 KNE00607.1 - 0.00045 20.4 0.1 0.36 11.1 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KNE00607.1 - 0.0011 18.6 0.1 1.7 8.6 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat U3_assoc_6 PF08640.6 KNE00607.1 - 0.0078 15.9 14.1 0.052 13.2 0.6 4.8 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 6 TPR_12 PF13424.1 KNE00607.1 - 0.016 15.1 2.4 4.8 7.1 0.0 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat HAT PF02184.11 KNE00607.1 - 0.058 13.1 39.7 0.27 10.9 0.3 9.4 9 2 0 9 9 9 0 HAT (Half-A-TPR) repeat ubiquitin PF00240.18 KNE00608.1 - 9.2e-22 76.2 0.0 1e-21 76.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KNE00608.1 - 4.4e-15 55.1 0.1 4.8e-15 54.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CTDII PF01556.13 KNE00608.1 - 0.064 13.1 0.5 0.81 9.6 0.2 2.1 1 1 1 2 2 2 0 DnaJ C terminal domain Ubiquitin_2 PF14560.1 KNE00608.1 - 0.085 13.1 0.0 0.11 12.7 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.4 KNE00608.1 - 0.091 12.9 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2217 PF10265.4 KNE00609.1 - 0.39 9.4 7.5 0.43 9.2 5.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) RecQ5 PF06959.6 KNE00609.1 - 0.45 10.1 9.6 0.54 9.8 6.6 1.0 1 0 0 1 1 1 0 RecQ helicase protein-like 5 (RecQ5) DEADboxA PF12343.3 KNE00609.1 - 0.53 10.5 7.9 0.72 10.1 5.4 1.4 1 1 0 1 1 1 0 Cold shock protein DEAD box A NPR3 PF03666.8 KNE00609.1 - 0.71 8.3 4.2 0.71 8.3 2.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nop53 PF07767.6 KNE00609.1 - 1.6 7.6 14.0 1.8 7.4 9.7 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) FAM209 PF15206.1 KNE00609.1 - 1.8 8.3 5.3 0.72 9.6 2.3 1.5 1 1 0 1 1 1 0 FAM209 family DUF3464 PF11947.3 KNE00609.1 - 1.9 7.9 6.3 1.8 7.9 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) SAGA-Tad1 PF12767.2 KNE00609.1 - 4.2 6.9 8.6 4.5 6.8 6.0 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF4544 PF15077.1 KNE00609.1 - 8.6 5.7 7.0 8.5 5.8 4.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) ABC2_membrane PF01061.19 KNE00610.1 - 1.6e-87 292.0 63.1 2.8e-47 160.6 14.0 2.8 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 KNE00610.1 - 1.3e-39 133.9 1.7 4.9e-34 116.0 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 KNE00610.1 - 5e-39 133.7 0.0 1.4e-18 67.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 KNE00610.1 - 1.5e-24 85.9 0.0 4.1e-24 84.4 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KNE00610.1 - 4.3e-09 36.0 0.0 0.00024 20.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KNE00610.1 - 8.1e-08 31.6 0.1 1.2e-05 24.5 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KNE00610.1 - 1.9e-05 24.1 0.8 0.02 14.3 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KNE00610.1 - 4.5e-05 23.5 0.2 0.0011 18.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.2 KNE00610.1 - 4.7e-05 22.5 8.7 4.7e-05 22.5 6.0 3.3 2 2 1 3 3 2 1 ABC-2 family transporter protein SMC_N PF02463.14 KNE00610.1 - 0.00031 20.0 0.0 0.57 9.3 0.0 3.3 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 KNE00610.1 - 0.00036 20.2 0.2 0.41 10.4 0.0 2.5 2 0 0 2 2 2 2 Part of AAA domain NACHT PF05729.7 KNE00610.1 - 0.00052 19.6 2.5 0.8 9.3 0.1 3.6 3 0 0 3 3 3 1 NACHT domain AAA_23 PF13476.1 KNE00610.1 - 0.00056 20.2 0.6 0.26 11.6 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KNE00610.1 - 0.0023 17.9 0.6 0.028 14.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KNE00610.1 - 0.0026 17.2 1.7 0.35 10.2 0.3 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 KNE00610.1 - 0.003 17.0 0.5 3.2 7.0 0.1 3.0 3 0 0 3 3 3 2 AAA-like domain AAA_22 PF13401.1 KNE00610.1 - 0.0033 17.5 0.3 0.25 11.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KNE00610.1 - 0.005 17.6 0.0 0.19 12.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KNE00610.1 - 0.0054 17.0 0.1 0.26 11.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KNE00610.1 - 0.0082 16.1 0.0 0.32 10.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain ABC2_membrane_2 PF12679.2 KNE00610.1 - 0.0084 15.0 0.4 0.0084 15.0 0.3 3.0 3 1 1 4 4 3 2 ABC-2 family transporter protein MMR_HSR1 PF01926.18 KNE00610.1 - 0.015 15.2 0.1 1.7 8.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.1 KNE00610.1 - 0.029 14.2 0.1 0.96 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KNE00610.1 - 0.033 13.8 0.3 0.23 11.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 KNE00610.1 - 0.04 13.4 0.0 4.2 6.7 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 KNE00610.1 - 0.04 13.6 0.0 7.4 6.1 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase AAA_15 PF13175.1 KNE00610.1 - 0.05 12.6 0.0 0.17 10.9 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Miro PF08477.8 KNE00610.1 - 0.058 13.8 0.1 10 6.6 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein AAA_30 PF13604.1 KNE00610.1 - 0.1 12.1 0.6 1.8 8.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 KNE00610.1 - 0.12 11.8 0.1 0.36 10.3 0.1 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 KNE00610.1 - 0.16 11.6 0.5 5.2 6.7 0.1 2.8 3 0 0 3 3 3 0 NTPase ABC_ATPase PF09818.4 KNE00610.1 - 0.25 9.9 0.3 1.8 7.0 0.0 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Thg1C PF14413.1 KNE00611.1 - 9.7e-52 173.7 1.4 1.3e-51 173.3 1.0 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 KNE00611.1 - 1.3e-42 144.5 0.2 2.5e-42 143.7 0.1 1.5 2 0 0 2 2 2 1 tRNAHis guanylyltransferase Gal-3-0_sulfotr PF06990.6 KNE00611.1 - 0.051 12.2 0.0 0.073 11.7 0.0 1.2 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase PWI PF01480.12 KNE00615.1 - 1.1e-05 25.4 0.9 3e-05 24.0 0.6 1.9 1 0 0 1 1 1 1 PWI domain UreE_N PF02814.10 KNE00619.1 - 0.17 11.3 3.2 0.27 10.7 2.2 1.3 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain DUF3052 PF11253.3 KNE00619.1 - 0.67 9.5 6.4 0.74 9.4 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) DUF3515 PF12028.3 KNE00621.1 - 0.13 11.4 0.6 0.14 11.4 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3515) L31 PF09784.4 KNE00625.1 - 5.4e-39 132.4 2.4 6.2e-39 132.2 1.6 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Spc24 PF08286.6 KNE00626.1 - 8.1e-27 93.2 13.4 4.6e-25 87.6 3.6 2.1 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 FlxA PF14282.1 KNE00626.1 - 0.023 14.6 20.0 0.46 10.4 4.8 2.5 1 1 1 2 2 2 0 FlxA-like protein AAA_13 PF13166.1 KNE00626.1 - 0.023 13.1 11.9 0.027 12.9 8.3 1.1 1 0 0 1 1 1 0 AAA domain Prefoldin_2 PF01920.15 KNE00626.1 - 0.048 13.4 11.7 0.093 12.5 2.1 2.6 2 0 0 2 2 2 0 Prefoldin subunit DUF4200 PF13863.1 KNE00626.1 - 0.072 13.0 11.6 0.58 10.1 2.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Snapin_Pallidin PF14712.1 KNE00626.1 - 0.075 13.3 0.7 0.075 13.3 0.5 2.5 2 0 0 2 2 2 0 Snapin/Pallidin V_ATPase_I PF01496.14 KNE00626.1 - 0.096 10.5 8.2 0.14 10.0 5.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pox_A_type_inc PF04508.7 KNE00626.1 - 0.11 12.3 3.4 0.11 12.3 0.3 2.7 3 0 0 3 3 1 0 Viral A-type inclusion protein repeat IncA PF04156.9 KNE00626.1 - 0.11 12.1 16.4 0.31 10.5 11.3 1.8 1 1 0 1 1 1 0 IncA protein DUF2894 PF11445.3 KNE00626.1 - 0.16 12.1 4.3 0.24 11.6 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) FliJ PF02050.11 KNE00626.1 - 0.16 11.9 8.9 0.47 10.5 0.9 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein DUF4337 PF14235.1 KNE00626.1 - 0.33 10.7 8.7 1.7 8.4 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF3068 PF11271.3 KNE00626.1 - 0.34 9.9 2.1 1.1 8.3 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3068) SYCE1 PF15233.1 KNE00626.1 - 0.41 10.5 11.3 0.75 9.7 7.8 1.5 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 Cortex-I_coil PF09304.5 KNE00626.1 - 0.44 10.6 16.3 0.18 11.8 2.2 2.9 2 1 1 3 3 3 0 Cortexillin I, coiled coil DUF4094 PF13334.1 KNE00626.1 - 0.46 10.8 6.7 0.24 11.7 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Rab5-bind PF09311.6 KNE00626.1 - 0.48 10.2 15.5 1.9 8.3 10.7 1.8 1 1 0 1 1 1 0 Rabaptin-like protein Lipoprotein_20 PF13942.1 KNE00626.1 - 0.57 9.7 11.6 0.087 12.3 2.7 2.3 1 1 1 2 2 2 0 YfhG lipoprotein Atg14 PF10186.4 KNE00626.1 - 0.59 9.0 13.6 0.097 11.5 3.4 2.1 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Filament PF00038.16 KNE00626.1 - 0.65 9.4 14.9 0.096 12.1 2.2 2.2 1 1 1 2 2 2 0 Intermediate filament protein DUF4407 PF14362.1 KNE00626.1 - 0.7 8.7 9.8 1.2 8.0 6.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_S2 PF00318.15 KNE00626.1 - 0.75 8.9 5.3 1.1 8.4 3.3 1.5 1 1 1 2 2 2 0 Ribosomal protein S2 NPV_P10 PF05531.7 KNE00626.1 - 0.89 9.8 9.2 4.9 7.4 4.9 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 KNE00626.1 - 1.3 8.1 6.8 0.6 9.2 0.6 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein CDC37_N PF03234.9 KNE00626.1 - 1.5 9.1 14.1 1.5 9.1 9.1 1.4 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Remorin_C PF03763.8 KNE00626.1 - 1.5 8.3 9.0 0.85 9.1 0.5 2.3 2 0 0 2 2 2 0 Remorin, C-terminal region Gon7 PF08738.5 KNE00626.1 - 1.5 8.8 7.4 11 6.1 1.4 2.4 2 0 0 2 2 2 0 Gon7 family XhlA PF10779.4 KNE00626.1 - 1.8 8.5 11.9 3.3 7.6 1.6 2.5 2 0 0 2 2 2 0 Haemolysin XhlA FliD_N PF02465.13 KNE00626.1 - 2.5 8.5 12.5 1.1e+02 3.2 8.8 2.4 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus SlyX PF04102.7 KNE00626.1 - 4.8 7.6 9.3 0.31 11.4 0.9 2.6 1 1 1 2 2 2 0 SlyX THOC7 PF05615.8 KNE00626.1 - 5 7.3 15.4 1.1 9.5 3.2 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 DivIC PF04977.10 KNE00626.1 - 5.1 6.6 11.1 0.96 8.9 1.6 3.1 2 1 0 2 2 2 0 Septum formation initiator Val_tRNA-synt_C PF10458.4 KNE00626.1 - 5.8 7.0 9.5 4.7 7.3 0.1 3.4 2 2 1 3 3 3 0 Valyl tRNA synthetase tRNA binding arm DUF651 PF04895.7 KNE00626.1 - 6.6 6.4 6.1 3.8 7.1 0.2 2.6 3 0 0 3 3 2 0 Archaeal protein of unknown function (DUF651) DUF3847 PF12958.2 KNE00626.1 - 7.6 6.3 13.3 0.76 9.5 2.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3847) ADIP PF11559.3 KNE00626.1 - 7.9 6.3 18.5 0.3 10.9 4.1 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4140 PF13600.1 KNE00626.1 - 7.9 6.9 9.6 2 8.9 2.8 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF2968 PF11180.3 KNE00626.1 - 8.1 5.7 11.3 0.64 9.3 2.6 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2968) DUF489 PF04356.7 KNE00626.1 - 9.7 5.7 9.5 1.3 8.5 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF489) Cmc1 PF08583.5 KNE00627.1 - 2.8e-15 55.8 6.8 2.8e-15 55.8 4.7 1.4 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.4 KNE00627.1 - 0.033 14.1 2.2 0.044 13.7 1.4 1.3 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Myticin-prepro PF10690.4 KNE00627.1 - 0.058 13.4 0.5 0.085 12.8 0.4 1.2 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel Suppressor_APC PF11414.3 KNE00627.1 - 0.14 11.9 3.5 0.25 11.1 2.4 1.3 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein DASH_Hsk3 PF08227.6 KNE00628.1 - 1.1e-11 44.7 0.7 1.4e-11 44.3 0.5 1.1 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Pet127 PF08634.5 KNE00628.1 - 0.085 12.0 0.2 0.093 11.8 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial protein Pet127 Avirulence PF03377.8 KNE00629.1 - 0.062 12.0 0.0 0.062 12.0 0.0 1.0 1 0 0 1 1 1 0 Xanthomonas avirulence protein, Avr/PthA Hap4_Hap_bind PF10297.4 KNE00630.1 - 3.3e-07 29.9 10.4 3.3e-07 29.9 7.2 2.2 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 LRR_4 PF12799.2 KNE00631.1 - 3.3e-19 68.0 57.2 7.8e-06 25.3 1.5 11.0 3 3 7 11 11 11 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KNE00631.1 - 5.3e-15 54.9 43.6 0.0028 17.3 4.4 9.0 4 4 5 9 9 9 8 Leucine rich repeat LRR_1 PF00560.28 KNE00631.1 - 9.5e-09 34.1 44.4 2.5 8.4 0.1 14.1 14 1 1 15 15 15 4 Leucine Rich Repeat FNIP PF05725.7 KNE00631.1 - 2.1e-08 34.0 16.9 0.018 15.0 0.0 7.7 7 0 0 7 7 7 3 FNIP Repeat LRR_6 PF13516.1 KNE00631.1 - 8.8e-06 25.2 44.1 0.28 11.3 0.5 13.3 13 2 2 15 15 15 3 Leucine Rich repeat LRR_7 PF13504.1 KNE00631.1 - 9.9e-06 24.9 44.8 6.5 7.4 0.0 15.5 16 1 1 17 17 17 1 Leucine rich repeat LRR_5 PF13306.1 KNE00631.1 - 2.5e-05 23.9 3.8 0.00069 19.3 0.0 3.6 3 0 0 3 3 3 1 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KNE00631.1 - 0.16 11.4 3.6 0.55 9.7 0.2 3.0 3 0 0 3 3 3 0 Leucine-rich repeat CcmD PF04995.9 KNE00632.1 - 0.2 11.4 3.0 0.5 10.1 2.1 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) FA_desaturase PF00487.19 KNE00632.1 - 0.76 9.1 6.8 0.81 9.0 4.7 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Sdh_cyt PF01127.17 KNE00634.1 - 5.6e-27 93.9 1.5 6.5e-27 93.7 1.1 1.0 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit FYVE PF01363.16 KNE00635.1 - 3.8e-16 58.7 6.5 7.8e-16 57.7 4.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.11 KNE00635.1 - 1 9.2 13.3 0.26 11.1 6.7 2.0 2 0 0 2 2 2 0 AN1-like Zinc finger STT3 PF02516.9 KNE00636.1 - 2.3e-139 465.5 44.2 5.6e-136 454.3 28.4 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit DUF962 PF06127.6 KNE00637.1 - 1.3e-24 85.8 0.1 2.5e-24 84.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF4084 PF13321.1 KNE00637.1 - 0.063 12.5 1.6 0.15 11.3 0.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4084) MT-A70 PF05063.9 KNE00638.1 - 3.8e-45 153.5 0.1 5.8e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 MT-A70 SHD1 PF03983.7 KNE00639.1 - 1e-34 117.9 0.0 1.8e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 KNE00639.1 - 5e-32 109.0 11.9 1.4e-11 43.6 0.1 4.3 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 KNE00639.1 - 4.1e-29 99.9 9.3 2.1e-10 40.0 0.1 4.2 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 KNE00639.1 - 4.6e-25 86.8 0.3 4.8e-08 32.3 0.0 4.4 4 0 0 4 4 4 3 Variant SH3 domain 2-Hacid_dh_C PF02826.14 KNE00640.1 - 1.1e-40 138.6 0.0 2e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KNE00640.1 - 1.4e-09 37.4 0.0 1.8e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.12 KNE00640.1 - 3.3e-05 24.2 0.0 0.00011 22.5 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 KNE00640.1 - 0.00054 19.3 0.1 0.0013 18.1 0.0 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 KNE00640.1 - 0.0019 18.0 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 KNE00640.1 - 0.0025 17.7 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.11 KNE00640.1 - 0.004 16.6 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AdoHcyase_NAD PF00670.16 KNE00640.1 - 0.0046 16.8 0.0 0.0083 15.9 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.1 KNE00640.1 - 0.08 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.22 KNE00640.1 - 0.096 13.0 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase COX5B PF01215.14 KNE00641.1 - 3.5e-42 143.3 0.0 3.7e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.4 KNE00641.1 - 0.15 11.9 1.4 0.24 11.2 1.0 1.4 1 0 0 1 1 1 0 Zinc-finger domain Ribosomal_S26e PF01283.14 KNE00642.1 - 3.7e-52 175.3 9.1 4.4e-52 175.1 6.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e mono-CXXC PF15626.1 KNE00642.1 - 0.022 14.6 1.0 0.07 13.0 0.7 1.9 1 0 0 1 1 1 0 single CXXC unit Fer4_7 PF12838.2 KNE00642.1 - 0.035 14.5 0.6 0.21 11.9 0.2 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain SRP19 PF01922.12 KNE00642.1 - 0.1 13.1 0.5 0.15 12.6 0.4 1.4 1 0 0 1 1 1 0 SRP19 protein Fer4_10 PF13237.1 KNE00642.1 - 0.13 12.0 2.7 0.13 12.0 0.3 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain WD40 PF00400.27 KNE00644.1 - 1.2e-11 44.0 0.3 0.0047 16.7 0.1 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoplasmin PF03066.10 KNE00644.1 - 0.77 9.2 5.2 5 6.6 3.3 2.1 2 0 0 2 2 2 0 Nucleoplasmin NOA36 PF06524.7 KNE00644.1 - 3.6 6.7 6.4 5.8 6.0 4.4 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.1 KNE00644.1 - 4.4 7.6 8.5 13 6.2 5.9 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LicD PF04991.8 KNE00646.1 - 2.4e-47 161.6 0.3 1.1e-46 159.5 0.1 2.2 2 0 0 2 2 2 1 LicD family BEX PF04538.7 KNE00646.1 - 1.3 9.3 4.7 4.9 7.4 0.1 2.7 2 1 0 2 2 2 0 Brain expressed X-linked like family ATE_C PF04377.10 KNE00649.1 - 1e-48 164.6 0.1 2.3e-48 163.4 0.0 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 KNE00649.1 - 5.8e-22 77.2 1.9 4e-21 74.6 1.5 2.1 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.1 KNE00649.1 - 0.079 12.9 0.2 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TFIIF_beta PF02270.10 KNE00650.1 - 8.4e-94 314.4 10.3 1.5e-93 313.5 7.1 1.4 1 1 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Prp18 PF02840.10 KNE00651.1 - 1.1e-34 119.3 0.1 1.1e-34 119.3 0.1 2.3 2 1 0 2 2 2 1 Prp18 domain ABC_tran_2 PF12848.2 KNE00651.1 - 0.016 15.0 3.0 0.048 13.4 2.0 1.8 1 0 0 1 1 1 0 ABC transporter Pex24p PF06398.6 KNE00652.1 - 1.9e-94 316.3 5.8 2.3e-94 316.1 4.0 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF2834 PF11196.3 KNE00652.1 - 0.02 15.0 1.1 0.068 13.3 0.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2834) SMC_N PF02463.14 KNE00653.1 - 1.5e-72 243.4 0.1 6.1e-71 238.1 0.0 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KNE00653.1 - 8.6e-19 67.6 0.4 5.5e-18 65.0 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KNE00653.1 - 6.4e-09 36.1 14.1 5.9e-07 29.7 0.6 4.7 2 2 2 4 4 4 2 AAA domain AAA_29 PF13555.1 KNE00653.1 - 3.7e-05 23.1 0.0 8.6e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 KNE00653.1 - 0.00049 19.3 35.1 0.028 13.5 0.6 5.5 3 2 1 5 5 5 3 Reovirus sigma C capsid protein AAA_13 PF13166.1 KNE00653.1 - 0.38 9.1 99.0 0.04 12.3 14.9 5.2 3 2 2 5 5 5 0 AAA domain NPV_P10 PF05531.7 KNE00653.1 - 1 9.6 40.7 1.6 9.0 0.5 9.3 6 2 4 10 10 10 0 Nucleopolyhedrovirus P10 protein AAA_23 PF13476.1 KNE00653.1 - 1.3 9.3 127.6 0.032 14.5 38.5 7.0 2 2 0 2 2 1 0 AAA domain DUF3135 PF11333.3 KNE00653.1 - 1.4 9.1 13.5 3.7 7.7 0.1 5.0 4 1 1 5 5 5 0 Protein of unknown function (DUF3135) YojJ PF10372.4 KNE00653.1 - 1.9 8.4 7.8 2.1 8.2 0.3 3.8 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus Filament PF00038.16 KNE00653.1 - 4.5 6.6 101.7 0.016 14.6 9.8 7.0 2 2 4 6 6 5 0 Intermediate filament protein Anp1 PF03452.9 KNE00654.1 - 2.3e-122 407.3 0.0 3.2e-122 406.8 0.0 1.1 1 0 0 1 1 1 1 Anp1 RhoGAP PF00620.22 KNE00655.1 - 1.3e-39 135.2 0.0 3.4e-39 133.8 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain ATG16 PF08614.6 KNE00655.1 - 0.011 15.5 5.1 0.011 15.5 3.5 3.9 4 0 0 4 4 4 0 Autophagy protein 16 (ATG16) TMCO5 PF14992.1 KNE00655.1 - 0.014 14.5 8.9 0.058 12.5 6.2 2.0 1 0 0 1 1 1 0 TMCO5 family APG6 PF04111.7 KNE00655.1 - 0.028 13.4 5.0 0.058 12.4 3.5 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 KNE00655.1 - 0.91 9.9 13.4 0.097 13.0 4.8 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF972) TMF_TATA_bd PF12325.3 KNE00655.1 - 1.2 8.9 15.1 0.86 9.3 1.1 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 KNE00655.1 - 4.2 6.9 7.5 13 5.3 5.2 1.8 1 0 0 1 1 1 0 IncA protein IGPD PF00475.13 KNE00657.1 - 1.8e-59 199.7 0.7 2.8e-59 199.1 0.5 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase SpoU_methylase PF00588.14 KNE00658.1 - 5.5e-23 81.4 0.0 9.5e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 KNE00658.1 - 3.5e-14 52.7 0.0 6.9e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding DUF531 PF04407.7 KNE00658.1 - 0.023 14.6 0.0 0.057 13.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF531) Aa_trans PF01490.13 KNE00659.1 - 4.6e-61 206.5 28.2 5.4e-61 206.2 19.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Med14 PF08638.6 KNE00660.1 - 4.4e-65 218.5 0.2 1.7e-64 216.6 0.1 2.1 1 0 0 1 1 1 1 Mediator complex subunit MED14 Pkinase PF00069.20 KNE00662.1 - 8.4e-47 159.4 0.0 1.2e-46 158.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE00662.1 - 2.4e-18 66.1 0.0 1.7e-11 43.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KNE00662.1 - 0.029 13.3 0.0 0.17 10.8 0.0 2.1 1 1 0 1 1 1 0 Kinase-like Surp PF01805.15 KNE00662.1 - 0.53 9.9 6.1 3.2 7.4 3.1 2.5 2 1 0 2 2 2 0 Surp module WD40 PF00400.27 KNE00666.1 - 6.5e-07 28.9 1.1 0.0059 16.4 0.0 4.5 4 1 0 4 4 4 2 WD domain, G-beta repeat PQQ_3 PF13570.1 KNE00666.1 - 0.23 11.7 2.0 23 5.4 0.0 4.0 5 0 0 5 5 5 0 PQQ-like domain SET PF00856.23 KNE00668.1 - 5.2e-08 33.3 0.1 5.2e-07 30.1 0.0 2.4 1 1 1 2 2 2 1 SET domain HTH_Crp_2 PF13545.1 KNE00668.1 - 0.015 15.1 0.0 1.5 8.7 0.0 2.7 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain DB PF01682.14 KNE00669.1 - 0.022 14.7 0.2 0.027 14.4 0.1 1.2 1 0 0 1 1 1 0 DB module Cmc1 PF08583.5 KNE00669.1 - 0.11 12.2 0.3 0.16 11.7 0.2 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Cyclin_N PF00134.18 KNE00671.1 - 8.1e-21 73.9 0.0 2e-20 72.6 0.0 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KNE00671.1 - 1.5e-12 48.1 0.0 1.5e-12 48.1 0.0 2.0 2 1 0 2 2 2 1 Cyclin Zn_clus PF00172.13 KNE00673.1 - 1.3e-09 37.8 10.5 2.4e-09 36.9 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KNE00674.1 - 1.1e-10 40.8 0.8 2.2e-10 39.8 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain TIMELESS PF04821.9 KNE00676.1 - 4.5e-45 153.9 2.1 5.3e-44 150.4 0.1 2.8 2 1 0 2 2 2 2 Timeless protein Aa_trans PF01490.13 KNE00677.1 - 1.8e-72 244.0 29.9 2.1e-72 243.8 20.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3392 PF11872.3 KNE00677.1 - 0.074 13.0 2.6 0.44 10.5 0.7 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3392) rRNA_processing PF08524.6 KNE00678.1 - 2.1e-33 115.1 38.0 4.1e-21 75.3 17.6 2.1 1 1 1 2 2 2 2 rRNA processing CheR_N PF03705.10 KNE00678.1 - 0.24 10.7 3.5 0.3 10.5 1.1 2.0 2 0 0 2 2 2 0 CheR methyltransferase, all-alpha domain AAA_23 PF13476.1 KNE00678.1 - 5.5 7.2 14.3 7.4 6.8 9.9 1.3 1 0 0 1 1 1 0 AAA domain DUF1423 PF07227.6 KNE00678.1 - 6.2 5.3 12.4 2.5 6.6 6.8 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1423) SpoIIIAH PF12685.2 KNE00678.1 - 6.5 6.1 16.6 9.4 5.6 11.5 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF4551 PF15087.1 KNE00678.1 - 8.2 4.6 13.6 9.1 4.5 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SOBP PF15279.1 KNE00678.1 - 9 6.5 12.5 11 6.2 8.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein ABC1 PF03109.11 KNE00679.1 - 5.8e-34 116.6 0.0 1.1e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 KNE00679.1 - 2e-05 24.0 0.0 0.00014 21.2 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Zn_clus PF00172.13 KNE00680.1 - 2.5e-07 30.4 9.6 2.5e-07 30.4 6.7 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LSM PF01423.17 KNE00681.1 - 1e-13 50.6 0.6 1.2e-13 50.3 0.4 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KNE00681.1 - 0.02 14.7 0.1 0.028 14.3 0.1 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Tail_tube PF10618.4 KNE00681.1 - 0.07 12.8 0.1 0.091 12.4 0.1 1.1 1 0 0 1 1 1 0 Phage tail tube protein Apc9 PF12856.2 KNE00682.1 - 1.8e-16 60.0 0.7 4.3e-16 58.8 0.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 9 DDE_Tnp_IS1595 PF12762.2 KNE00682.1 - 0.013 15.3 0.4 0.031 14.1 0.3 1.6 1 0 0 1 1 1 0 ISXO2-like transposase domain Glutaredoxin PF00462.19 KNE00685.1 - 6.7e-13 48.4 0.0 1.5e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin Peptidase_C93 PF06035.6 KNE00685.1 - 0.025 14.0 0.3 0.061 12.7 0.2 1.6 1 1 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP Brix PF04427.13 KNE00685.1 - 0.028 14.0 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Brix domain Malate_synthase PF01274.17 KNE00688.1 - 1.2e-224 746.2 0.0 1.3e-224 746.0 0.0 1.0 1 0 0 1 1 1 1 Malate synthase CMAS PF02353.15 KNE00689.1 - 3.4e-57 193.6 0.1 4.2e-57 193.3 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KNE00689.1 - 1.1e-12 48.0 0.0 2.2e-12 47.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNE00689.1 - 1e-06 29.1 0.0 1.8e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNE00689.1 - 1.9e-06 28.4 0.0 3.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNE00689.1 - 6.3e-06 25.8 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNE00689.1 - 1.9e-05 25.0 0.0 3.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 KNE00689.1 - 0.0013 18.0 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 KNE00689.1 - 0.0014 18.6 0.0 0.0041 17.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNE00689.1 - 0.003 17.8 0.0 0.0054 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KNE00689.1 - 0.0031 17.5 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 KNE00689.1 - 0.011 15.0 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF2628 PF10947.3 KNE00689.1 - 0.02 14.6 0.5 0.062 13.0 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) O-antigen_lig PF13425.1 KNE00689.1 - 0.055 13.4 3.5 0.065 13.2 0.1 2.4 3 0 0 3 3 3 0 O-antigen ligase like membrane protein COX7C PF02935.11 KNE00689.1 - 0.11 12.2 0.2 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc SIR2 PF02146.12 KNE00691.1 - 7.1e-64 214.7 0.0 1.1e-63 214.1 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 KNE00691.1 - 2.9e-26 91.8 4.6 1.2e-12 47.6 1.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 KNE00691.1 - 1.1e-05 25.2 0.1 0.016 15.0 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF164 PF02591.10 KNE00691.1 - 0.019 14.7 1.8 0.055 13.3 1.2 1.8 1 0 0 1 1 1 0 Putative zinc ribbon domain HypA PF01155.14 KNE00691.1 - 0.054 13.1 0.3 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family RNHCP PF12647.2 KNE00691.1 - 0.081 12.7 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 RNHCP domain zf-ribbon_3 PF13248.1 KNE00691.1 - 0.25 10.6 1.7 0.5 9.6 1.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Tmemb_55A PF09788.4 KNE00691.1 - 0.26 10.3 2.2 0.62 9.1 0.3 2.1 2 0 0 2 2 2 0 Transmembrane protein 55A HLH PF00010.21 KNE00693.1 - 1.2e-16 60.1 0.0 2.2e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3263 PF11662.3 KNE00693.1 - 0.021 14.3 0.4 2.5 7.6 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3263) DDHD PF02862.12 KNE00693.1 - 0.077 12.7 2.1 0.09 12.5 1.5 1.2 1 0 0 1 1 1 0 DDHD domain Suf PF05843.9 KNE00693.1 - 0.99 9.0 3.8 3.6 7.2 0.3 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PAPS_reduct PF01507.14 KNE00694.1 - 2e-20 73.3 0.0 5.3e-18 65.4 0.0 2.1 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family zf-met PF12874.2 KNE00696.1 - 2.3e-07 30.7 0.3 9.9e-07 28.7 0.3 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Ank_4 PF13637.1 KNE00697.1 - 0.0001 22.6 0.3 1.1 9.8 0.0 4.2 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KNE00697.1 - 0.00082 19.6 2.0 0.029 14.6 0.3 3.2 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) KilA-N PF04383.8 KNE00697.1 - 0.0096 15.5 1.3 0.021 14.4 0.0 2.2 2 0 0 2 2 2 1 KilA-N domain Ank_5 PF13857.1 KNE00697.1 - 0.013 15.7 0.1 3.8 7.9 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.25 KNE00697.1 - 0.3 10.9 3.8 10 6.1 0.1 3.3 3 0 0 3 3 3 0 Ankyrin repeat Fib_alpha PF08702.5 KNE00697.1 - 1.3 9.1 9.8 5.7 7.0 3.8 2.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family EF-hand_6 PF13405.1 KNE00698.1 - 1.1e-15 55.9 4.4 1.2e-05 24.7 0.2 5.0 4 1 1 5 5 5 4 EF-hand domain EF-hand_7 PF13499.1 KNE00698.1 - 1.6e-14 53.7 6.1 5.9e-11 42.3 0.9 3.6 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 KNE00698.1 - 1.1e-12 46.2 6.7 6.5e-06 25.0 0.2 5.5 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 KNE00698.1 - 7.8e-09 35.0 2.3 0.00064 19.2 0.1 4.3 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 KNE00698.1 - 0.00015 21.4 0.5 0.24 11.1 0.1 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.1 KNE00698.1 - 0.00054 19.1 13.1 0.17 11.2 0.0 5.3 6 0 0 6 6 6 2 EF hand S10_plectin PF03501.10 KNE00698.1 - 0.0061 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Plectin/S10 domain Sdh5 PF03937.11 KNE00699.1 - 1.1e-26 92.2 1.7 1.8e-26 91.5 1.1 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase HTH_24 PF13412.1 KNE00699.1 - 0.063 12.6 0.4 4.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF605 PF04652.11 KNE00700.1 - 1.3e-58 199.2 5.8 2.5e-58 198.3 4.0 1.4 1 1 0 1 1 1 1 Vta1 like DUF438 PF04282.8 KNE00700.1 - 0.0012 18.6 1.7 0.032 14.0 0.2 2.4 2 0 0 2 2 2 1 Family of unknown function (DUF438) DUF4452 PF14618.1 KNE00700.1 - 0.021 14.6 0.4 0.039 13.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) Slu7 PF11708.3 KNE00701.1 - 2.8e-39 135.2 9.9 3.6e-39 134.9 6.8 1.1 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor Nop52 PF05997.7 KNE00702.1 - 2.8e-58 196.9 7.8 7.6e-58 195.4 5.4 1.6 1 1 0 1 1 1 1 Nucleolar protein,Nop52 PIG-S PF10510.4 KNE00702.1 - 0.076 11.6 0.3 0.11 11.2 0.2 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Astro_capsid PF03115.9 KNE00702.1 - 0.18 10.0 6.1 0.23 9.6 4.3 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Tom37_C PF11801.3 KNE00702.1 - 0.53 10.1 7.6 0.87 9.4 4.8 1.7 1 1 0 1 1 1 0 Tom37 C-terminal domain Sporozoite_P67 PF05642.6 KNE00702.1 - 1.2 6.9 9.1 1.7 6.4 6.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pox_RNA_Pol_19 PF05320.7 KNE00702.1 - 1.5 8.5 10.6 3.9 7.1 7.4 1.7 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit YqfQ PF14181.1 KNE00702.1 - 1.8 8.5 7.6 3 7.8 5.3 1.3 1 0 0 1 1 1 0 YqfQ-like protein TRAP_alpha PF03896.11 KNE00702.1 - 4.7 6.1 8.3 7.3 5.5 5.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF1510 PF07423.6 KNE00702.1 - 5.1 6.3 13.9 9.5 5.5 9.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CENP-B_dimeris PF09026.5 KNE00702.1 - 5.8 7.2 23.7 0.22 11.7 10.1 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Daxx PF03344.10 KNE00702.1 - 7.2 4.9 15.9 9.6 4.5 11.0 1.3 1 0 0 1 1 1 0 Daxx Family SecE PF00584.15 KNE00703.1 - 0.00082 18.9 0.1 0.00086 18.8 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex ATP13 PF12921.2 KNE00704.1 - 9.1e-24 83.2 0.1 2.3e-23 81.9 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ATPase expression DUF4252 PF14060.1 KNE00704.1 - 0.043 13.3 0.1 0.17 11.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4252) ECH PF00378.15 KNE00705.1 - 4.2e-24 85.0 0.0 6.2e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DEAD PF00270.24 KNE00706.1 - 7.6e-46 155.6 0.0 5.9e-45 152.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNE00706.1 - 5.1e-21 74.3 0.0 1.8e-20 72.5 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KNE00706.1 - 6e-05 21.9 0.0 0.00011 21.0 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KNE00706.1 - 0.047 13.5 0.0 0.19 11.5 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AA_permease PF00324.16 KNE00707.1 - 5.6e-48 163.4 39.4 7.3e-48 163.0 27.3 1.1 1 0 0 1 1 1 1 Amino acid permease CarbpepA_inh PF02977.10 KNE00710.1 - 0.042 13.4 0.1 0.054 13.0 0.1 1.2 1 0 0 1 1 1 0 Carboxypeptidase A inhibitor DUF1546 PF07571.8 KNE00711.1 - 2.2e-28 98.2 0.0 5.3e-28 96.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 KNE00711.1 - 1.5e-25 88.9 0.0 1.6e-24 85.5 0.0 2.5 3 0 0 3 3 3 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 KNE00711.1 - 0.00037 20.5 0.0 0.0014 18.7 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KNE00711.1 - 0.005 16.8 0.2 0.014 15.4 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SLD3 PF08639.5 KNE00712.1 - 9.4e-36 123.4 21.9 1.8e-35 122.5 15.2 1.5 1 1 0 1 1 1 1 DNA replication regulator SLD3 Pkinase PF00069.20 KNE00713.1 - 1.9e-58 197.6 0.0 3.4e-58 196.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE00713.1 - 7.8e-21 74.3 0.0 1.2e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNE00713.1 - 1.4e-07 30.8 0.0 2.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PAS PF00989.19 KNE00713.1 - 0.0015 18.3 0.0 1.3 8.8 0.0 2.7 2 0 0 2 2 2 2 PAS fold Kdo PF06293.9 KNE00713.1 - 0.003 16.6 0.0 0.0075 15.3 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.1 KNE00713.1 - 0.0037 17.6 0.1 0.25 11.7 0.0 3.5 4 0 0 4 4 4 1 PAS domain APH PF01636.18 KNE00713.1 - 0.0087 15.8 0.1 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family LDB19 PF13002.2 KNE00714.1 - 2e-57 193.7 0.3 3.1e-57 193.1 0.2 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Actin PF00022.14 KNE00716.1 - 2.1e-63 214.0 0.0 2.6e-63 213.7 0.0 1.1 1 0 0 1 1 1 1 Actin PIG-L PF02585.12 KNE00718.1 - 2.3e-22 79.8 0.0 3.3e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Methyltransf_31 PF13847.1 KNE00719.1 - 9.3e-16 57.7 0.0 1.4e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNE00719.1 - 1.1e-15 57.8 0.0 2.1e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNE00719.1 - 4.2e-13 49.5 0.0 9.9e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KNE00719.1 - 1.3e-10 40.8 0.0 2.1e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KNE00719.1 - 9.1e-10 38.8 0.0 1.8e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNE00719.1 - 8.2e-09 35.3 0.0 1.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNE00719.1 - 2.1e-07 31.5 0.0 4.5e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNE00719.1 - 8.4e-05 22.5 0.0 0.00056 19.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KNE00719.1 - 0.00019 20.8 0.0 0.001 18.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 KNE00719.1 - 0.0081 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Fungal_trans PF04082.13 KNE00720.1 - 1.6e-32 112.4 0.5 3.4e-32 111.3 0.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNE00720.1 - 2.5e-10 40.1 11.7 5.4e-10 39.0 8.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HhH-GPD PF00730.20 KNE00721.1 - 3.8e-18 65.7 0.0 8.4e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KNE00721.1 - 5.3e-05 22.6 0.0 0.00012 21.5 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF356 PF04009.7 KNE00721.1 - 0.0001 22.3 0.4 0.00019 21.4 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF356) Exo_endo_phos PF03372.18 KNE00722.1 - 9.6e-15 55.1 0.1 1.2e-14 54.9 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KNE00722.1 - 0.091 12.3 0.0 0.22 11.1 0.0 1.7 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase DNA_pack_N PF02500.10 KNE00723.1 - 0.039 13.5 0.9 0.049 13.1 0.6 1.1 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus Exo_endo_phos PF03372.18 KNE00724.1 - 5.4e-22 78.9 0.0 7.8e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.1 KNE00724.1 - 1.1e-21 76.3 16.2 2.6e-11 43.0 1.2 2.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KNE00724.1 - 8.5e-17 60.3 6.6 1.4e-09 37.3 0.3 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KNE00724.1 - 1.7e-10 39.3 9.3 0.0086 15.9 0.0 4.8 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 KNE00724.1 - 5.8e-09 34.7 2.9 0.12 12.6 0.0 4.2 3 0 0 3 3 3 3 Leucine rich repeat LRR_6 PF13516.1 KNE00724.1 - 0.00013 21.6 0.8 7.1 7.0 0.0 4.0 3 0 0 3 3 3 1 Leucine Rich repeat Exo_endo_phos_2 PF14529.1 KNE00724.1 - 0.029 13.9 0.0 0.11 12.1 0.0 2.0 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase His_Phos_1 PF00300.17 KNE00725.1 - 3.2e-13 50.0 0.4 3.2e-13 50.0 0.3 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) CDI PF02234.14 KNE00725.1 - 0.033 13.9 3.3 1.2 8.9 0.7 2.7 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor AF0941-like PF14591.1 KNE00725.1 - 0.15 12.1 0.9 0.86 9.6 0.1 2.2 2 0 0 2 2 2 0 AF0941-like Sugar_tr PF00083.19 KNE00726.1 - 1.7e-27 96.1 36.2 1.9e-24 86.0 25.1 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNE00726.1 - 1e-18 67.2 38.2 8.8e-11 41.1 9.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_2 PF04909.9 KNE00729.1 - 3.6e-06 26.7 0.1 6.6e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KNE00729.1 - 1e-05 25.7 0.0 2.4e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase DIM1 PF02966.11 KNE00731.1 - 5.4e-69 229.8 0.7 6.1e-69 229.6 0.5 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 PBP PF01161.15 KNE00732.1 - 6.2e-33 113.6 0.5 7.7e-33 113.4 0.3 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein CBFD_NFYB_HMF PF00808.18 KNE00734.1 - 4.5e-19 68.2 1.0 7.2e-19 67.6 0.7 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KNE00734.1 - 1.2e-12 47.7 0.1 1.7e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 KNE00734.1 - 0.012 15.4 0.1 0.02 14.7 0.1 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X PMT PF02366.13 KNE00735.1 - 1.2e-73 247.4 24.4 1.2e-73 247.4 16.9 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KNE00735.1 - 1.4e-25 89.9 0.0 2.1e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 MIR domain PhzC-PhzF PF02567.11 KNE00736.1 - 3e-56 190.7 0.0 3.3e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.6 KNE00736.1 - 1.8e-09 36.9 0.0 4.5e-07 29.0 0.0 2.3 2 1 0 2 2 2 2 Proline racemase Mcp5_PH PF12814.2 KNE00739.1 - 9.7e-37 125.6 2.4 1e-36 125.5 0.2 2.3 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology bZIP_1 PF00170.16 KNE00739.1 - 3.7 7.5 26.1 6.1 6.8 1.5 6.0 5 0 0 5 5 5 0 bZIP transcription factor EF-hand_1 PF00036.27 KNE00740.1 - 3.5e-28 94.7 4.4 5.2e-09 34.7 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 KNE00740.1 - 1.2e-26 92.0 3.3 2.5e-11 43.0 0.3 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.1 KNE00740.1 - 2.2e-24 85.3 1.7 6.1e-17 61.5 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KNE00740.1 - 1.5e-21 74.6 4.3 1.1e-08 34.0 0.0 3.4 3 1 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KNE00740.1 - 4.5e-17 60.3 2.9 2.8e-08 32.9 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_9 PF14658.1 KNE00740.1 - 1.2e-08 34.6 0.1 0.00047 20.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KNE00740.1 - 3.8e-07 29.8 1.9 0.0035 17.0 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 KNE00740.1 - 1.1e-06 28.1 0.0 0.021 14.4 0.0 3.0 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.4 KNE00740.1 - 1.3e-06 28.4 0.1 0.00015 21.7 0.0 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.8 KNE00740.1 - 0.00019 21.2 0.5 0.0022 17.7 0.1 2.0 1 1 0 2 2 2 1 Tellurite resistance protein TerB EF-hand_10 PF14788.1 KNE00740.1 - 0.0029 17.2 1.0 0.0053 16.3 0.0 1.9 2 1 0 2 2 2 1 EF hand Dockerin_1 PF00404.13 KNE00740.1 - 0.057 13.1 12.1 3 7.6 0.1 3.5 3 0 0 3 3 3 0 Dockerin type I repeat VCBS PF13517.1 KNE00740.1 - 0.16 12.3 3.3 1.2 9.5 2.3 2.2 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PB1 PF00564.19 KNE00740.1 - 0.18 11.4 0.7 23 4.7 0.1 2.7 2 1 1 3 3 3 0 PB1 domain DUF533 PF04391.7 KNE00740.1 - 0.31 10.4 2.0 1.8 7.9 0.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF533) DUF1296 PF06972.6 KNE00740.1 - 0.38 10.7 2.1 2.9 7.9 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1296) IMS PF00817.15 KNE00742.1 - 2.3e-35 121.5 0.1 1.6e-34 118.8 0.0 2.3 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 KNE00742.1 - 1.2e-15 57.5 0.0 2.8e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT PF00533.21 KNE00742.1 - 1.5e-05 25.0 0.1 4.9e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Glyco_trans_1_4 PF13692.1 KNE00743.1 - 1e-13 51.5 0.0 2e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KNE00743.1 - 3.1e-12 46.2 0.0 4.5e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KNE00743.1 - 0.00064 19.9 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KNE00743.1 - 0.03 14.4 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain zf-CCCH PF00642.19 KNE00744.1 - 1.1e-09 37.6 1.9 2.4e-09 36.6 1.3 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 KNE00744.1 - 6.4e-09 35.6 12.1 1.3e-08 34.6 8.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KNE00744.1 - 3.9e-07 29.7 9.9 1e-06 28.4 6.9 1.7 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KNE00744.1 - 4.7e-07 29.4 11.0 1.1e-06 28.2 7.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KNE00744.1 - 9.4e-07 28.4 8.8 1.8e-06 27.5 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KNE00744.1 - 1.7e-05 24.6 10.5 3.8e-05 23.4 7.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KNE00744.1 - 1.8e-05 24.2 12.3 4.3e-05 23.0 8.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KNE00744.1 - 2.7e-05 23.8 5.0 2.7e-05 23.8 3.4 2.9 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_6 PF14835.1 KNE00744.1 - 0.034 13.9 2.9 0.063 13.0 2.0 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 KNE00744.1 - 0.11 11.9 8.8 0.26 10.8 6.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 KNE00744.1 - 0.21 11.1 11.7 2.4 7.8 0.4 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 KNE00744.1 - 3 7.4 9.3 29 4.2 6.5 2.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DUF4112 PF13430.1 KNE00745.1 - 8.2e-27 93.2 0.2 1.1e-26 92.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) CTP_transf_2 PF01467.21 KNE00746.1 - 1.4e-21 77.2 0.0 1.2e-09 38.3 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 KNE00746.1 - 0.005 16.4 0.0 0.19 11.3 0.0 2.3 2 0 0 2 2 2 1 FAD synthetase HABP4_PAI-RBP1 PF04774.10 KNE00747.1 - 0.00027 21.4 1.3 0.00027 21.4 0.9 1.4 1 1 1 2 2 2 1 Hyaluronan / mRNA binding family RWD PF05773.17 KNE00748.1 - 2.5e-15 56.3 0.1 4.5e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 KNE00748.1 - 1.8e-14 53.3 37.7 5e-09 35.9 1.7 4.6 3 1 1 4 4 4 2 IBR domain zf-RING_5 PF14634.1 KNE00748.1 - 2e-05 24.2 9.5 2e-05 24.2 6.6 4.1 3 2 1 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.1 KNE00748.1 - 5.4e-05 22.9 8.2 5.4e-05 22.9 5.7 4.6 4 1 1 5 5 5 1 Ring finger domain zf-C3HC4 PF00097.20 KNE00748.1 - 6.2e-05 22.5 5.4 6.2e-05 22.5 3.8 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KNE00748.1 - 0.00014 21.8 9.0 0.00014 21.8 6.2 5.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KNE00748.1 - 4.7 7.0 12.6 0.13 12.0 3.3 2.7 2 0 0 2 2 2 0 RING-type zinc-finger CN_hydrolase PF00795.17 KNE00749.1 - 3.2e-13 49.4 0.0 5.1e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Rav1p_C PF12234.3 KNE00750.1 - 1.1e-175 585.4 6.9 1.6e-175 584.9 4.8 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal MFS_1 PF07690.11 KNE00751.1 - 2.4e-11 42.9 48.2 3.6e-08 32.5 20.9 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily UNC-93 PF05978.11 KNE00751.1 - 6.2e-05 22.5 7.5 6.2e-05 22.5 5.2 2.9 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 Herpes_UL73 PF03554.8 KNE00751.1 - 0.0007 19.3 3.6 0.13 12.0 0.2 3.3 2 0 0 2 2 2 2 UL73 viral envelope glycoprotein Pyridoxal_deC PF00282.14 KNE00753.1 - 2.9e-76 256.3 0.0 3.7e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KNE00753.1 - 9.3e-06 24.6 0.0 1.4e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KNE00753.1 - 6.5e-05 22.2 0.0 8.4e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KNE00753.1 - 0.05 12.6 0.0 0.068 12.1 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF2962 PF11176.3 KNE00754.1 - 0.086 12.3 0.2 0.097 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2962) CPSF_A PF03178.10 KNE00755.1 - 1.8e-68 230.9 0.6 4.8e-68 229.6 0.4 1.8 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 KNE00755.1 - 2.8e-33 114.8 2.6 7.9e-33 113.3 1.3 1.9 1 1 1 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Fork_head PF00250.13 KNE00756.1 - 1.2e-38 131.0 1.4 2.4e-38 130.0 0.9 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KNE00756.1 - 6.6e-09 35.7 0.0 1.7e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 FHA domain WD40 PF00400.27 KNE00757.1 - 4.2e-10 39.1 7.0 0.0013 18.4 0.7 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.6 KNE00757.1 - 7.9e-08 32.2 3.1 0.003 17.2 0.6 3.3 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A EMP24_GP25L PF01105.19 KNE00758.1 - 1.7e-36 125.6 0.0 2.2e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Vps8 PF12816.2 KNE00759.1 - 3.3e-51 173.3 3.1 3.3e-51 173.3 2.1 2.6 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 zf-C3HC4_2 PF13923.1 KNE00759.1 - 0.028 14.4 4.2 0.088 12.8 2.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.27 KNE00759.1 - 0.048 13.5 0.1 0.25 11.3 0.1 2.3 1 0 0 1 1 1 0 WD domain, G-beta repeat zf-rbx1 PF12678.2 KNE00759.1 - 0.06 13.4 3.4 0.2 11.8 2.4 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_5 PF14634.1 KNE00759.1 - 0.22 11.2 6.4 0.11 12.2 2.4 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.1 KNE00759.1 - 3.3 7.5 6.7 1.2 8.9 2.1 2.2 2 0 0 2 2 2 0 Ring finger domain Chitin_synth_1 PF01644.12 KNE00760.1 - 2.2e-65 219.4 0.1 3.2e-65 218.8 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KNE00760.1 - 5.9e-25 86.7 0.1 1.6e-24 85.4 0.0 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KNE00760.1 - 1.1e-23 83.4 3.6 5.7e-19 67.9 0.0 3.4 3 2 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KNE00760.1 - 6.9e-16 58.5 4.3 6.9e-16 58.5 3.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KNE00760.1 - 1.2e-09 38.3 0.0 3.3e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KNE00760.1 - 0.00058 19.5 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KNE00760.1 - 0.00094 18.5 0.0 0.0032 16.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 DUF3989 PF13150.1 KNE00760.1 - 5.8 6.4 7.2 0.93 8.9 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) SnAC PF14619.1 KNE00762.1 - 0.52 10.5 4.5 0.62 10.2 3.1 1.1 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex E1-E2_ATPase PF00122.15 KNE00763.1 - 1.8e-63 213.6 8.8 3.6e-63 212.6 6.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KNE00763.1 - 3.4e-23 83.1 0.1 6.7e-23 82.2 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KNE00763.1 - 1.2e-14 54.9 0.0 2.8e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KNE00763.1 - 2.1e-10 39.9 0.0 4.9e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KNE00763.1 - 0.002 17.7 0.1 0.002 17.7 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KNE00763.1 - 0.039 13.9 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit UreE_N PF02814.10 KNE00763.1 - 0.062 12.8 0.1 11 5.5 0.0 2.5 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain PUF PF00806.14 KNE00765.1 - 1.1e-61 200.9 2.2 1e-08 34.1 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat HTH_16 PF12645.2 KNE00765.1 - 0.024 14.5 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Fungal_trans_2 PF11951.3 KNE00766.1 - 8.6e-11 41.0 0.6 1.4e-09 37.0 0.5 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNE00766.1 - 1.7e-09 37.3 12.8 3.3e-09 36.5 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MHC_II_alpha PF00993.15 KNE00766.1 - 0.064 12.8 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 Class II histocompatibility antigen, alpha domain ERG4_ERG24 PF01222.12 KNE00767.1 - 1.8e-158 527.6 23.7 2e-158 527.4 16.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family CytoC_RC PF02276.13 KNE00767.1 - 0.041 12.9 0.1 0.064 12.3 0.1 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit Proteasome PF00227.21 KNE00768.1 - 1.8e-33 115.4 0.1 2.1e-33 115.2 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Hist_deacetyl PF00850.14 KNE00769.1 - 3.1e-81 273.0 0.0 4.2e-81 272.6 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Pkinase PF00069.20 KNE00770.1 - 1.1e-56 191.8 0.8 1.5e-56 191.4 0.5 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE00770.1 - 3.3e-32 111.5 0.1 6e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNE00770.1 - 0.00058 18.9 0.0 0.0017 17.3 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Tricorn_C1 PF14684.1 KNE00770.1 - 0.11 12.3 0.2 0.31 10.9 0.1 1.7 1 0 0 1 1 1 0 Tricorn protease C1 domain Rhodanese PF00581.15 KNE00772.1 - 3e-11 43.6 0.0 7.5e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain adh_short PF00106.20 KNE00774.1 - 2.5e-67 225.9 4.6 3.6e-33 114.8 0.2 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KNE00774.1 - 3.5e-34 118.0 1.4 4.9e-16 58.9 0.1 2.2 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 KNE00774.1 - 7.9e-31 105.9 0.0 1.6e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain adh_short_C2 PF13561.1 KNE00774.1 - 7.1e-15 55.4 0.2 2.7e-07 30.5 0.0 3.1 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KNE00774.1 - 0.02 14.3 1.9 0.75 9.1 0.1 2.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family RRM_4 PF10598.4 KNE00774.1 - 0.064 13.1 0.1 0.76 9.6 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif of the spliceosomal PrP8 UBN_AB PF14075.1 KNE00774.1 - 0.15 11.7 0.2 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Nucleoplasmin PF03066.10 KNE00774.1 - 0.34 10.4 10.3 0.68 9.4 7.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 KNE00774.1 - 0.66 8.3 9.0 0.97 7.8 6.2 1.1 1 0 0 1 1 1 0 Daxx Family Sigma70_ner PF04546.8 KNE00774.1 - 2.1 7.8 12.3 4.8 6.7 8.5 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 KNE00774.1 - 3.7 6.7 7.8 6.2 5.9 5.4 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 KNE00774.1 - 4.2 5.9 12.2 6.1 5.4 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 KNE00774.1 - 6 4.6 12.7 8.2 4.2 8.8 1.1 1 0 0 1 1 1 0 Nop14-like family Dicty_REP PF05086.7 KNE00774.1 - 7.5 4.1 6.3 11 3.6 4.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Toxin_2 PF00451.14 KNE00775.1 - 0.73 9.9 8.6 0.38 10.8 4.3 1.7 2 0 0 2 2 2 0 Scorpion short toxin, BmKK2 Acyltransferase PF01553.16 KNE00776.1 - 4.9e-10 38.9 0.0 2.8e-09 36.4 0.0 2.1 1 1 0 1 1 1 1 Acyltransferase Rtf2 PF04641.7 KNE00776.1 - 0.0042 16.3 1.4 0.0067 15.6 1.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger DNA_ligase_A_M PF01068.16 KNE00777.1 - 5.7e-58 195.6 0.1 9e-58 194.9 0.1 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KNE00777.1 - 1.3e-54 184.7 0.2 4.4e-54 182.9 0.0 1.9 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KNE00777.1 - 1.3e-25 89.5 0.0 2.9e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 KNE00777.1 - 0.008 15.8 0.9 3.4 7.4 0.1 2.8 2 0 0 2 2 2 2 DNA ligase OB-like domain Actin PF00022.14 KNE00778.1 - 2e-23 82.4 0.0 6.5e-23 80.7 0.0 1.6 1 1 0 1 1 1 1 Actin ChpXY PF10216.4 KNE00779.1 - 0.0075 15.1 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 CO2 hydration protein (ChpXY) DUF3812 PF12757.2 KNE00780.1 - 1.4e-21 76.7 6.9 1.4e-21 76.7 4.8 6.6 2 1 4 6 6 6 1 Protein of unknown function (DUF3812) GHMP_kinases_N PF00288.21 KNE00780.1 - 0.068 13.2 1.7 0.27 11.3 1.2 2.0 1 0 0 1 1 1 0 GHMP kinases N terminal domain G3P_acyltransf PF02660.10 KNE00781.1 - 0.069 12.7 0.4 0.089 12.3 0.3 1.1 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase Neuregulin PF02158.10 KNE00782.1 - 0.098 11.4 0.7 0.14 10.9 0.3 1.3 1 1 0 1 1 1 0 Neuregulin family Histone PF00125.19 KNE00783.1 - 2.1e-29 101.4 0.2 3e-29 100.9 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KNE00783.1 - 0.0002 21.5 0.0 0.0003 20.9 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KNE00783.1 - 0.0052 16.8 0.6 0.01 15.8 0.4 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KNE00783.1 - 0.0082 15.4 0.0 0.01 15.0 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 KNE00783.1 - 0.077 12.7 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit zf-C2H2 PF00096.21 KNE00784.1 - 2.5e-13 49.5 13.6 6.1e-07 29.4 1.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNE00784.1 - 2.2e-11 43.2 11.5 2.9e-06 27.2 1.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KNE00784.1 - 1.5e-09 37.6 20.5 2.4e-06 27.5 3.7 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KNE00784.1 - 4.3e-09 36.2 6.2 0.0014 18.7 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KNE00784.1 - 2.6e-05 24.2 4.5 0.13 12.5 0.0 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-BED PF02892.10 KNE00784.1 - 5e-05 22.9 5.0 0.004 16.8 1.0 2.6 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_6 PF13912.1 KNE00784.1 - 0.00016 21.4 8.6 0.046 13.6 2.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KNE00784.1 - 0.0016 18.4 5.1 0.059 13.4 0.6 2.3 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) DUF535 PF04393.8 KNE00784.1 - 0.069 12.0 0.1 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF535) PyrI_C PF02748.10 KNE00784.1 - 0.1 12.0 1.8 0.23 10.9 0.3 2.3 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF3613 PF12266.3 KNE00784.1 - 0.12 11.8 0.4 0.42 10.1 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3613) Zn-ribbon_8 PF09723.5 KNE00784.1 - 0.19 11.7 2.8 7.7 6.5 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-CHCC PF10276.4 KNE00784.1 - 0.33 10.8 3.3 1 9.2 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger domain zf-Di19 PF05605.7 KNE00784.1 - 0.36 10.9 10.8 0.2 11.8 5.0 2.3 2 1 1 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding DUF629 PF04780.7 KNE00784.1 - 1.6 7.1 6.2 4.1 5.8 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-H2C2_5 PF13909.1 KNE00784.1 - 3.6 7.9 12.5 9 6.7 1.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DUF4137 PF13593.1 KNE00787.1 - 1.1e-118 395.9 17.2 1.2e-118 395.7 12.0 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 KNE00787.1 - 1.6e-06 27.6 7.4 1.6e-06 27.6 5.1 2.5 1 1 1 2 2 2 1 Sodium Bile acid symporter family Colicin_im PF03857.8 KNE00787.1 - 0.55 9.9 8.0 0.05 13.3 1.8 1.9 2 0 0 2 2 2 0 Colicin immunity protein FCH PF00611.18 KNE00789.1 - 1e-16 60.9 1.1 4.4e-16 58.8 0.5 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 KNE00789.1 - 2.8e-10 39.4 0.1 5.2e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KNE00789.1 - 2.9e-07 29.9 0.1 6e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KNE00789.1 - 6e-05 22.4 0.1 0.00013 21.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Aldo_ket_red PF00248.16 KNE00790.1 - 4.3e-44 150.4 0.0 5.1e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PC4 PF02229.11 KNE00791.1 - 1.3e-19 69.1 0.9 2.1e-19 68.4 0.6 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) CorA PF01544.13 KNE00792.1 - 8.1e-36 123.5 4.5 3.2e-17 62.5 0.1 3.7 3 1 0 3 3 3 3 CorA-like Mg2+ transporter protein CotJB PF12652.2 KNE00792.1 - 0.45 10.6 8.6 0.51 10.4 1.9 2.6 2 0 0 2 2 2 0 CotJB protein Bap31 PF05529.7 KNE00793.1 - 6.8e-51 172.4 5.6 7.7e-51 172.2 3.9 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Atg14 PF10186.4 KNE00793.1 - 0.022 13.7 1.5 0.026 13.4 1.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF641 PF04859.7 KNE00793.1 - 0.088 12.5 3.3 0.15 11.7 2.3 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Tnp_P_element PF12017.3 KNE00793.1 - 0.091 11.9 1.3 0.16 11.1 0.9 1.3 1 0 0 1 1 1 0 Transposase protein Seryl_tRNA_N PF02403.17 KNE00793.1 - 0.28 11.1 3.9 0.52 10.3 2.7 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain KilA-N PF04383.8 KNE00794.1 - 1.7e-05 24.3 0.0 0.00018 21.0 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain Suc_Fer-like PF06999.7 KNE00796.1 - 3.7e-43 148.1 0.0 4.5e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like SNF2_N PF00176.18 KNE00797.1 - 5.6e-72 242.0 0.0 1.1e-71 241.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KNE00797.1 - 1.4e-16 60.1 0.0 3.5e-16 58.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_11 PF13086.1 KNE00797.1 - 0.08 12.5 0.0 0.08 12.5 0.0 3.8 3 1 1 4 4 4 0 AAA domain Grp1_Fun34_YaaH PF01184.14 KNE00798.1 - 2e-88 295.1 16.8 2.4e-88 294.9 11.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family adh_short PF00106.20 KNE00801.1 - 3.9e-26 91.9 0.0 5.5e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNE00801.1 - 2.5e-14 53.6 0.0 3.2e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KNE00801.1 - 1.6e-08 34.4 0.0 3.4e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KNE00801.1 - 0.002 17.9 0.1 0.0043 16.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KNE00801.1 - 0.0033 16.8 0.0 0.0087 15.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CoA_binding_2 PF13380.1 KNE00801.1 - 0.018 15.2 0.0 0.052 13.7 0.0 1.7 2 0 0 2 2 2 0 CoA binding domain DUF1776 PF08643.5 KNE00801.1 - 0.085 11.9 0.0 0.27 10.3 0.0 1.8 2 1 0 2 2 2 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KNE00801.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.6 2 0 0 2 2 2 0 NADH(P)-binding Pkinase PF00069.20 KNE00802.1 - 2e-52 177.9 0.0 1.2e-51 175.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE00802.1 - 1.7e-26 92.8 0.0 2.9e-19 69.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 KNE00802.1 - 4.5e-06 27.0 1.1 4.5e-06 27.0 0.7 2.2 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 KNE00802.1 - 6.3e-06 25.3 0.0 0.0016 17.4 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KNE00802.1 - 0.0034 17.1 0.0 0.033 13.9 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KNE00802.1 - 0.02 13.9 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNase_PH PF01138.16 KNE00803.1 - 3e-16 59.9 0.3 5.3e-16 59.1 0.2 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KNE00803.1 - 0.00014 21.6 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Prp31_C PF09785.4 KNE00804.1 - 1.1e-27 96.9 4.8 1.1e-27 96.9 3.4 1.8 2 0 0 2 2 2 1 Prp31 C terminal domain Nop PF01798.13 KNE00804.1 - 1.7e-26 92.3 0.0 3.6e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KNE00804.1 - 1.6e-15 56.6 0.2 1.1e-13 50.7 0.0 2.6 2 0 0 2 2 2 1 NOSIC (NUC001) domain DICT PF10069.4 KNE00804.1 - 0.074 12.5 0.1 0.32 10.5 0.1 1.9 2 0 0 2 2 2 0 Sensory domain found in DIguanylate Cyclases & Two-component systems K-box PF01486.12 KNE00804.1 - 6 6.7 8.3 0.097 12.4 0.2 2.3 3 0 0 3 3 3 0 K-box region tRNA-synt_1 PF00133.17 KNE00805.1 - 1e-227 756.9 3.3 7e-227 754.2 2.3 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KNE00805.1 - 5.4e-37 126.8 0.2 5.4e-37 126.8 0.2 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KNE00805.1 - 1.3e-18 66.8 1.6 3.6e-09 35.7 0.1 4.8 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KNE00805.1 - 9.7e-11 41.2 16.6 3.6e-08 32.9 0.0 4.4 4 1 1 5 5 5 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 KNE00805.1 - 0.47 9.5 0.0 0.47 9.5 0.0 3.5 4 1 0 4 4 4 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1c PF00749.16 KNE00805.1 - 2.1 6.9 14.5 1.5 7.3 0.0 4.4 4 0 0 4 4 4 0 tRNA synthetases class I (E and Q), catalytic domain HAD PF12710.2 KNE00809.1 - 4.9e-24 85.5 0.0 8.5e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KNE00809.1 - 6.9e-24 85.4 0.0 2.2e-23 83.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KNE00809.1 - 8.2e-21 74.0 0.0 2e-20 72.8 0.0 1.6 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KNE00809.1 - 2.2e-06 27.5 0.0 6.8e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KNE00809.1 - 0.00018 21.1 0.0 0.00063 19.4 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KNE00809.1 - 0.02 14.1 0.0 0.043 13.1 0.0 1.5 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase IF-2B PF01008.12 KNE00810.1 - 5.4e-55 186.3 0.0 1.7e-54 184.7 0.0 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family Pex2_Pex12 PF04757.9 KNE00811.1 - 6.8e-57 192.5 12.7 1.6e-56 191.3 8.3 1.8 2 0 0 2 2 2 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 KNE00811.1 - 1.9e-05 24.4 2.9 3.6e-05 23.5 2.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KNE00811.1 - 0.00012 22.0 1.9 0.00012 22.0 1.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KNE00811.1 - 0.017 14.9 0.2 0.041 13.7 0.1 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 KNE00811.1 - 0.018 14.6 2.3 0.037 13.7 1.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KNE00811.1 - 0.027 14.1 0.3 0.054 13.1 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4123 PF13503.1 KNE00811.1 - 0.066 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) CDC45 PF02724.9 KNE00811.1 - 0.28 9.1 1.7 0.4 8.6 1.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4637 PF15470.1 KNE00811.1 - 3.4 7.2 6.2 7.1 6.2 4.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Not3 PF04065.10 KNE00813.1 - 5.9e-31 107.5 15.3 1e-30 106.7 10.6 1.4 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 KNE00813.1 - 0.025 14.4 7.4 0.37 10.6 0.0 3.3 3 0 0 3 3 3 0 NOT2 / NOT3 / NOT5 family HSP70 PF00012.15 KNE00814.1 - 1.9e-260 864.9 18.2 2.2e-260 864.7 12.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KNE00814.1 - 2e-19 69.3 3.2 1.6e-18 66.3 0.8 2.3 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 KNE00814.1 - 0.00017 20.5 1.5 0.0008 18.3 1.0 2.0 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 KNE00814.1 - 0.00051 19.2 10.3 0.0045 16.1 0.1 3.8 3 1 0 4 4 4 2 Hydantoinase/oxoprolinase cNMP_binding PF00027.24 KNE00815.1 - 3e-45 151.9 0.1 3.7e-23 81.1 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 KNE00815.1 - 2.9e-08 32.9 1.0 7.8e-08 31.6 0.7 1.8 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit RtcB PF01139.12 KNE00815.1 - 0.045 12.7 0.0 0.073 12.0 0.0 1.2 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB MATH PF00917.21 KNE00815.1 - 0.14 12.3 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 MATH domain Erg28 PF03694.8 KNE00816.1 - 8.7e-44 148.0 0.3 1e-43 147.8 0.2 1.1 1 0 0 1 1 1 1 Erg28 like protein Mito_carr PF00153.22 KNE00817.1 - 1.4e-66 220.2 1.5 1.4e-21 75.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ammonium_transp PF00909.16 KNE00818.1 - 9.4e-75 251.5 26.6 2.4e-44 151.4 8.8 2.0 2 0 0 2 2 2 2 Ammonium Transporter Family PLA2_B PF01735.13 KNE00819.1 - 1.4e-96 323.6 6.8 1.1e-73 248.0 0.0 2.1 1 1 0 2 2 2 2 Lysophospholipase catalytic domain ABC_tran PF00005.22 KNE00820.1 - 1.3e-45 155.0 0.8 6e-23 81.6 0.0 4.7 4 2 0 4 4 2 2 ABC transporter AAA_21 PF13304.1 KNE00820.1 - 1.2e-17 64.7 0.0 0.0024 17.8 0.0 4.9 5 0 0 5 5 4 4 AAA domain SMC_N PF02463.14 KNE00820.1 - 4.2e-15 55.5 0.1 2.1e-05 23.8 0.0 4.1 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KNE00820.1 - 2.1e-10 41.2 0.3 0.0017 18.6 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KNE00820.1 - 9.4e-10 37.8 0.0 0.0015 17.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KNE00820.1 - 2.1e-09 36.7 0.0 0.0001 21.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KNE00820.1 - 1.6e-08 35.3 0.3 0.0033 18.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 KNE00820.1 - 6.3e-08 32.4 0.2 0.01 15.7 0.0 4.5 4 1 0 4 4 4 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 KNE00820.1 - 7.2e-08 32.6 0.2 0.0028 17.8 0.0 4.0 5 1 0 5 5 2 2 AAA domain AAA_28 PF13521.1 KNE00820.1 - 9.8e-08 32.1 0.0 0.0022 17.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KNE00820.1 - 1.9e-07 30.4 1.2 0.43 9.5 0.0 5.0 4 1 1 5 5 5 2 AAA ATPase domain AAA_10 PF12846.2 KNE00820.1 - 3.2e-07 30.0 0.1 0.19 11.1 0.0 3.8 4 0 0 4 4 4 2 AAA-like domain MMR_HSR1 PF01926.18 KNE00820.1 - 3.8e-07 30.0 0.0 0.0066 16.3 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.1 KNE00820.1 - 5.8e-06 26.2 0.0 0.15 11.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain ArgK PF03308.11 KNE00820.1 - 7.5e-06 24.9 0.2 0.065 12.0 0.0 2.9 3 0 0 3 3 3 2 ArgK protein AAA_18 PF13238.1 KNE00820.1 - 1e-05 25.8 1.5 0.064 13.5 0.0 4.3 5 0 0 5 5 3 1 AAA domain RNA_helicase PF00910.17 KNE00820.1 - 1.1e-05 25.5 0.0 0.16 12.1 0.0 3.2 3 0 0 3 3 2 2 RNA helicase Dynamin_N PF00350.18 KNE00820.1 - 1.1e-05 25.3 0.0 0.001 18.9 0.0 3.1 3 0 0 3 3 2 1 Dynamin family Miro PF08477.8 KNE00820.1 - 1.5e-05 25.4 0.0 0.094 13.2 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein HEAT_2 PF13646.1 KNE00820.1 - 1.5e-05 25.1 2.1 0.0033 17.6 0.0 3.7 1 1 2 3 3 3 1 HEAT repeats AAA_16 PF13191.1 KNE00820.1 - 2.8e-05 24.1 0.0 0.15 12.0 0.0 3.9 4 0 0 4 4 4 1 AAA ATPase domain MobB PF03205.9 KNE00820.1 - 3.4e-05 23.5 0.0 0.28 10.8 0.0 3.3 4 0 0 4 4 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 KNE00820.1 - 5.7e-05 23.3 0.4 0.45 10.7 0.0 4.3 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KNE00820.1 - 0.00016 21.4 0.0 0.43 10.2 0.0 3.1 2 0 0 2 2 2 2 Archaeal ATPase MutS_V PF00488.16 KNE00820.1 - 0.00028 20.3 0.0 0.15 11.4 0.0 2.4 2 0 0 2 2 2 1 MutS domain V AAA_14 PF13173.1 KNE00820.1 - 0.00034 20.5 0.0 2.7 7.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain Cnd1 PF12717.2 KNE00820.1 - 0.00039 20.3 0.2 0.0024 17.7 0.0 2.4 2 1 0 2 2 1 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 KNE00820.1 - 0.0011 17.3 7.1 0.02 13.2 1.4 3.0 2 1 1 3 3 3 1 Adaptin N terminal region NACHT PF05729.7 KNE00820.1 - 0.0013 18.4 0.0 0.64 9.6 0.0 2.6 2 0 0 2 2 2 1 NACHT domain PduV-EutP PF10662.4 KNE00820.1 - 0.0014 18.0 0.0 0.19 11.2 0.0 2.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 KNE00820.1 - 0.0014 18.4 4.8 0.35 10.6 0.0 4.5 5 0 0 5 5 3 1 Domain of unknown function DUF87 AAA_30 PF13604.1 KNE00820.1 - 0.0019 17.7 0.0 3 7.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain cobW PF02492.14 KNE00820.1 - 0.005 16.2 0.0 3.1 7.1 0.0 3.0 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 KNE00820.1 - 0.0059 15.7 0.1 3.2 6.8 0.0 3.2 3 1 0 3 3 3 0 Zeta toxin ParcG PF10274.4 KNE00820.1 - 0.0075 16.1 0.2 0.39 10.6 0.1 2.7 2 0 0 2 2 2 1 Parkin co-regulated protein MMS19_C PF12460.3 KNE00820.1 - 0.011 14.4 0.4 0.18 10.4 0.1 2.3 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal HEAT PF02985.17 KNE00820.1 - 0.012 15.5 1.2 27 5.1 0.0 4.2 4 0 0 4 4 3 0 HEAT repeat Mg_chelatase PF01078.16 KNE00820.1 - 0.019 14.1 0.1 1 8.4 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI CLASP_N PF12348.3 KNE00820.1 - 0.026 13.8 1.0 0.23 10.7 0.1 2.6 2 1 0 2 2 2 0 CLASP N terminal Septin PF00735.13 KNE00820.1 - 0.038 13.0 0.7 2 7.3 0.0 3.0 4 0 0 4 4 4 0 Septin AAA_19 PF13245.1 KNE00820.1 - 0.04 13.6 0.0 6.2 6.6 0.0 3.0 2 0 0 2 2 2 0 Part of AAA domain GTP_EFTU PF00009.22 KNE00820.1 - 0.049 13.0 0.0 9 5.6 0.0 2.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 KNE00820.1 - 0.056 12.9 0.1 3.6 7.0 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.12 KNE00820.1 - 0.061 12.7 0.0 7.2 5.9 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein UME PF08064.8 KNE00820.1 - 0.066 13.1 0.2 0.16 11.9 0.2 1.7 1 0 0 1 1 1 0 UME (NUC010) domain P16-Arc PF04699.9 KNE00820.1 - 0.07 13.1 0.3 0.95 9.4 0.1 2.4 2 0 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) ATP_bind_1 PF03029.12 KNE00820.1 - 0.12 11.8 1.6 8.1 5.9 0.0 3.0 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein DUF3349 PF11829.3 KNE00820.1 - 0.29 11.6 2.3 0.94 9.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) HEAT_EZ PF13513.1 KNE00820.1 - 1.2 9.7 4.6 16 6.1 0.1 4.1 3 2 1 5 5 2 0 HEAT-like repeat AAA_13 PF13166.1 KNE00820.1 - 2 6.7 14.2 2.1 6.6 0.0 4.5 4 1 0 5 5 5 0 AAA domain Flavoprotein PF02441.14 KNE00821.1 - 2.2e-41 140.5 0.2 7.8e-40 135.5 0.7 2.7 2 1 0 2 2 2 1 Flavoprotein CDC45 PF02724.9 KNE00821.1 - 2.1 6.3 31.2 4.3 5.2 21.6 1.5 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KNE00821.1 - 4.1 5.1 46.7 6.7 4.4 32.4 1.2 1 0 0 1 1 1 0 Nop14-like family Ydc2-catalyt PF09159.5 KNE00822.1 - 1.8e-38 132.5 0.0 2.6e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 U1snRNP70_N PF12220.3 KNE00823.1 - 1 9.6 7.8 5.7 7.3 1.2 2.1 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal UPF0239 PF06783.6 KNE00823.1 - 3.3 7.6 8.6 0.18 11.7 0.4 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) Chorion_3 PF05387.6 KNE00825.1 - 3.5 6.9 9.1 3.6 6.9 6.3 1.0 1 0 0 1 1 1 0 Chorion family 3 Gram_pos_anchor PF00746.16 KNE00825.1 - 7.3 6.5 9.9 0.99 9.2 3.1 2.1 2 0 0 2 2 2 0 Gram positive anchor PLA2_B PF01735.13 KNE00826.1 - 3.5e-200 665.3 2.1 4.2e-200 665.0 1.4 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain TRM PF02005.11 KNE00827.1 - 8.9e-119 396.7 0.0 1.2e-118 396.3 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase DUF2083 PF09856.4 KNE00827.1 - 0.053 13.1 0.1 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Predicted transcriptional regulator (DUF2083) Pox_int_trans PF05718.7 KNE00827.1 - 0.1 11.0 1.4 0.14 10.6 0.0 1.8 2 0 0 2 2 2 0 Poxvirus intermediate transcription factor Tox-REase-7 PF15649.1 KNE00829.1 - 0.0052 16.8 0.2 0.009 16.1 0.1 1.4 1 0 0 1 1 1 1 Restriction endonuclease fold toxin 7 BNIP2 PF12496.3 KNE00830.1 - 0.15 12.2 0.5 0.18 11.9 0.3 1.1 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 zf-DHHC PF01529.15 KNE00832.1 - 8.9e-31 106.6 7.2 8.9e-31 106.6 5.0 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase CorA PF01544.13 KNE00832.1 - 0.11 11.5 1.9 0.2 10.6 1.3 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF3953 PF13129.1 KNE00832.1 - 0.11 12.1 0.1 0.11 12.1 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3953) DUF1131 PF06572.7 KNE00832.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) DREPP PF05558.7 KNE00833.1 - 0.12 12.1 1.2 0.54 10.0 0.1 2.1 2 0 0 2 2 2 0 DREPP plasma membrane polypeptide Glyco_hydro_81 PF03639.8 KNE00834.1 - 2.1e-214 713.5 2.6 2.6e-214 713.2 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Fungal_trans PF04082.13 KNE00835.1 - 2.4e-28 98.7 3.1 6.8e-28 97.2 2.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNE00835.1 - 2.1e-06 27.4 11.6 3.8e-06 26.7 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-DHHC PF01529.15 KNE00835.1 - 0.047 13.0 1.0 0.12 11.7 0.7 1.7 1 0 0 1 1 1 0 DHHC palmitoyltransferase ARPC4 PF05856.7 KNE00836.1 - 2.1e-14 53.2 0.3 2.2e-14 53.1 0.2 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) FF PF01846.14 KNE00837.1 - 1.5e-21 76.0 19.8 7.5e-08 32.2 0.0 5.9 6 0 0 6 6 6 4 FF domain WW PF00397.21 KNE00837.1 - 8.3e-21 73.5 11.9 6.9e-11 41.8 1.4 2.8 2 0 0 2 2 2 2 WW domain BNR PF02012.15 KNE00840.1 - 2.1e-09 35.7 43.0 0.097 12.5 0.3 11.7 11 0 0 11 11 11 6 BNR/Asp-box repeat CHB_HEX_C_1 PF13290.1 KNE00840.1 - 0.0013 18.4 2.2 5.8 6.7 0.0 4.6 5 0 0 5 5 5 2 Chitobiase/beta-hexosaminidase C-terminal domain PSII_BNR PF14870.1 KNE00840.1 - 0.37 9.7 8.0 10 5.0 0.2 4.6 4 3 2 6 6 6 0 Photosynthesis system II assembly factor YCF48 Rax2 PF12768.2 KNE00841.1 - 5.1e-80 268.6 1.3 5.1e-80 268.6 0.9 4.1 5 1 1 6 6 6 3 Cortical protein marker for cell polarity NB PF04159.8 KNE00842.1 - 0.089 12.5 0.2 0.1 12.3 0.1 1.1 1 0 0 1 1 1 0 NB glycoprotein TRAPPC-Trs85 PF12739.2 KNE00843.1 - 4.4e-98 328.6 2.1 5.9e-98 328.2 1.5 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF1751 PF08551.5 KNE00844.1 - 3.3e-17 62.6 2.5 3.3e-17 62.6 1.8 2.3 3 0 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 KNE00844.1 - 0.0057 16.6 10.0 0.0057 16.6 6.9 1.7 2 0 0 2 2 2 1 Rhomboid family MCM PF00493.18 KNE00846.1 - 7.9e-137 455.4 0.3 7.9e-137 455.4 0.2 2.1 3 0 0 3 3 3 1 MCM2/3/5 family MCM_N PF14551.1 KNE00846.1 - 7.9e-23 81.2 2.1 4.3e-22 78.8 0.2 3.0 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 KNE00846.1 - 1.5e-06 27.5 0.0 0.00019 20.6 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KNE00846.1 - 7.4e-06 25.7 0.1 3.9e-05 23.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KNE00846.1 - 0.00035 20.1 0.0 0.0052 16.3 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KNE00846.1 - 0.016 14.7 0.1 2.8 7.3 0.0 3.7 4 0 0 4 4 4 0 Sigma-54 interaction domain DUF3356 PF11836.3 KNE00846.1 - 0.06 13.1 0.8 0.39 10.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3356) Ldh_1_N PF00056.18 KNE00849.1 - 1.8e-44 150.9 0.5 2.7e-44 150.3 0.4 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KNE00849.1 - 1.4e-31 109.5 0.0 2.3e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 KNE00849.1 - 0.0047 15.6 0.0 0.0076 14.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 KNE00849.1 - 0.052 12.8 0.2 1.1 8.5 0.1 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase MFS_1 PF07690.11 KNE00850.1 - 2e-26 92.5 27.0 2e-26 92.5 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Beta-lactamase PF00144.19 KNE00851.1 - 1.3e-51 175.5 0.0 1.8e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Histidinol_dh PF00815.15 KNE00852.1 - 3.6e-180 599.0 2.3 4.9e-180 598.5 1.6 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 KNE00852.1 - 4.2e-22 77.5 0.1 9.8e-22 76.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 KNE00852.1 - 2e-12 47.1 0.1 2e-12 47.1 0.1 2.4 3 0 0 3 3 3 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 KNE00852.1 - 0.0055 16.6 0.2 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain TPR_11 PF13414.1 KNE00853.1 - 9.7e-26 89.2 11.8 1.7e-12 46.8 0.0 4.7 2 2 3 5 5 5 5 TPR repeat TPR_1 PF00515.23 KNE00853.1 - 1.1e-22 78.5 1.2 5.3e-06 25.8 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 KNE00853.1 - 3.7e-18 64.1 3.8 0.00097 19.1 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 KNE00853.1 - 4e-16 57.5 5.2 0.0024 17.6 0.0 6.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 KNE00853.1 - 6.9e-15 54.2 9.1 8.4e-05 22.8 0.0 6.2 4 2 3 7 7 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 KNE00853.1 - 4.1e-13 49.4 3.0 0.0053 17.0 0.0 5.1 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 KNE00853.1 - 3.4e-12 46.6 3.2 0.00011 22.7 0.0 4.6 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 KNE00853.1 - 5.7e-08 32.5 1.8 2.5e-05 24.0 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 KNE00853.1 - 8.5e-07 29.0 6.5 0.02 14.9 0.0 5.1 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 KNE00853.1 - 9.9e-07 28.5 0.5 0.0035 17.1 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KNE00853.1 - 2.9e-06 26.6 0.5 1.3 8.9 0.0 4.6 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KNE00853.1 - 6.5e-05 22.4 0.2 0.98 9.3 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KNE00853.1 - 0.0003 20.8 0.9 0.1 12.7 0.0 2.9 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KNE00853.1 - 0.0026 18.1 6.1 21 5.8 0.0 6.0 7 0 0 7 7 5 0 Tetratricopeptide repeat MIT PF04212.13 KNE00853.1 - 0.023 14.5 0.1 1.6 8.6 0.0 3.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain CCP_MauG PF03150.9 KNE00853.1 - 0.32 11.2 9.5 0.54 10.5 3.1 2.5 1 1 1 2 2 2 0 Di-haem cytochrome c peroxidase AChE_tetra PF08674.5 KNE00853.1 - 3.4 7.2 5.5 25 4.5 0.1 3.6 4 0 0 4 4 4 0 Acetylcholinesterase tetramerisation domain Ring_hydroxyl_A PF00848.14 KNE00854.1 - 1.1e-34 119.8 0.3 1.9e-34 119.1 0.2 1.3 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 KNE00854.1 - 3.1e-16 58.7 0.1 8.9e-16 57.2 0.0 1.8 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain ARID PF01388.16 KNE00855.1 - 3.3e-15 55.7 0.4 1.3e-14 53.7 0.1 2.3 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Glyco_transf_34 PF05637.7 KNE00856.1 - 4.2e-67 226.1 0.1 5e-67 225.8 0.1 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF2172 PF09940.4 KNE00856.1 - 0.11 10.8 0.0 0.19 10.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2172) Pex2_Pex12 PF04757.9 KNE00857.1 - 2.8e-33 115.2 1.4 3.5e-33 114.9 1.0 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 KNE00857.1 - 2.1e-09 37.0 14.4 3.3e-09 36.4 10.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KNE00857.1 - 1.2e-08 34.8 13.9 2.1e-08 34.0 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KNE00857.1 - 1.1e-06 28.1 12.8 1.9e-06 27.3 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KNE00857.1 - 1.2e-06 28.0 14.3 1.8e-06 27.5 9.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNE00857.1 - 1.9e-05 24.2 10.3 3.1e-05 23.6 7.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KNE00857.1 - 0.0011 18.7 13.1 0.0021 17.9 9.1 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KNE00857.1 - 0.0025 17.8 11.9 0.0051 16.8 8.2 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KNE00857.1 - 0.025 14.2 4.0 0.025 14.2 2.8 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 KNE00857.1 - 0.15 11.7 12.0 0.28 10.7 8.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 KNE00857.1 - 0.19 11.5 7.2 0.35 10.6 5.0 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 KNE00857.1 - 0.83 9.5 8.1 1.3 8.8 5.6 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger IBR PF01485.16 KNE00857.1 - 2.4 8.1 10.8 7.2 6.5 7.5 1.8 1 1 0 1 1 1 0 IBR domain IMS PF00817.15 KNE00858.1 - 1.6e-37 128.5 0.0 2.9e-37 127.7 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KNE00858.1 - 2.2e-07 30.8 0.1 5.4e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Ferric_reduct PF01794.14 KNE00859.1 - 7.2e-10 39.0 14.9 7.2e-10 39.0 10.3 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KNE00859.1 - 1e-09 38.5 0.0 2e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KNE00859.1 - 5.5e-08 32.6 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Curto_V2 PF07325.6 KNE00859.1 - 0.0087 15.7 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 Curtovirus V2 protein NAD_binding_1 PF00175.16 KNE00859.1 - 0.019 15.5 0.0 1.5 9.4 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Imm49 PF15660.1 KNE00860.1 - 0.079 13.0 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 49 Peptidase_S49_N PF08496.5 KNE00863.1 - 0.37 10.5 1.6 0.35 10.6 1.1 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ada_Zn_binding PF02805.11 KNE00865.1 - 5.6e-06 25.8 3.0 1e-05 25.0 2.1 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 KNE00865.1 - 0.00019 21.1 0.0 0.00051 19.7 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 KNE00865.1 - 0.00033 20.6 0.1 0.001 19.1 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain Pkinase PF00069.20 KNE00868.1 - 6.4e-72 241.8 0.0 9.3e-72 241.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE00868.1 - 3.2e-38 131.2 0.0 4.7e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNE00868.1 - 1.3e-09 37.4 0.0 1.1e-06 27.8 0.0 2.2 1 1 1 2 2 2 2 Kinase-like YrbL-PhoP_reg PF10707.4 KNE00868.1 - 0.018 14.3 0.0 0.043 13.1 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 KNE00868.1 - 0.055 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nif11 PF07862.6 KNE00868.1 - 0.084 12.8 0.0 0.084 12.8 0.0 3.6 5 0 0 5 5 5 0 Nitrogen fixation protein of unknown function Aminotran_3 PF00202.16 KNE00871.1 - 1.6e-94 316.5 0.0 1.9e-94 316.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KNE00871.1 - 0.0013 17.7 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II SpoVAE PF14097.1 KNE00872.1 - 0.093 12.1 0.0 0.097 12.0 0.0 1.0 1 0 0 1 1 1 0 Stage V sporulation protein AE1 SRI PF08236.6 KNE00875.1 - 5.5e-28 96.7 1.5 5.5e-28 96.7 1.1 2.6 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.23 KNE00875.1 - 1.5e-22 80.6 0.1 1.5e-22 80.6 0.1 3.6 2 2 0 2 2 2 1 SET domain WW PF00397.21 KNE00875.1 - 2.8e-08 33.4 0.8 5.9e-08 32.4 0.6 1.6 1 0 0 1 1 1 1 WW domain Med26 PF08711.6 KNE00875.1 - 0.007 15.8 2.8 0.014 14.8 1.1 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain DUF2116 PF09889.4 KNE00875.1 - 1.9 8.3 8.9 1.4 8.7 3.7 2.7 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) NAD_Gly3P_dh_N PF01210.18 KNE00876.1 - 1.6e-50 170.8 0.0 2.4e-50 170.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 KNE00876.1 - 5.7e-46 155.9 0.3 8.9e-46 155.3 0.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 KNE00876.1 - 0.0048 17.2 0.0 1.8 9.0 0.0 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 KNE00876.1 - 0.051 13.0 0.0 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Semialdhyde_dh PF01118.19 KNE00876.1 - 0.095 13.0 0.0 0.57 10.4 0.0 2.1 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DNA_ligase_A_N PF04675.9 KNE00876.1 - 0.13 12.0 0.0 0.36 10.6 0.0 1.6 2 0 0 2 2 2 0 DNA ligase N terminus zf-C2H2 PF00096.21 KNE00878.1 - 8.6e-10 38.3 7.7 0.00022 21.3 1.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNE00878.1 - 4.7e-07 29.6 2.4 0.0092 16.2 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KNE00878.1 - 0.037 14.2 0.4 2.8 8.2 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-LYAR PF08790.6 KNE00878.1 - 0.059 13.0 0.4 5.9 6.6 0.0 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.1 KNE00878.1 - 6.4 6.8 5.7 10 6.1 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger ING PF12998.2 KNE00880.1 - 4.4e-22 78.3 0.0 7.9e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KNE00880.1 - 1.3e-08 34.3 7.8 2.2e-08 33.6 5.4 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KNE00880.1 - 0.017 14.4 2.1 0.029 13.6 1.4 1.4 1 0 0 1 1 1 0 PHD-finger Ras PF00071.17 KNE00881.1 - 2.4e-57 192.8 0.1 2.9e-57 192.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNE00881.1 - 3.1e-19 69.6 0.0 4.6e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNE00881.1 - 6.7e-10 38.4 0.0 8e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KNE00881.1 - 1.2e-06 28.1 0.1 6.1e-06 25.7 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KNE00881.1 - 1e-05 25.4 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KNE00881.1 - 0.00025 20.2 0.0 0.00031 19.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 KNE00881.1 - 0.00078 18.7 0.7 0.01 15.0 0.5 2.6 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_25 PF13481.1 KNE00881.1 - 0.032 13.6 0.1 0.18 11.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KNE00881.1 - 0.047 12.6 0.2 0.58 9.0 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) Septin PF00735.13 KNE00881.1 - 0.055 12.4 0.1 0.25 10.3 0.0 1.9 2 1 0 2 2 2 0 Septin DUF258 PF03193.11 KNE00881.1 - 0.11 11.6 0.3 0.19 10.9 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 DAD PF02109.11 KNE00882.1 - 2.3e-40 137.1 4.0 3.1e-40 136.7 2.8 1.2 1 0 0 1 1 1 1 DAD family ATP_synt_I PF03899.10 KNE00882.1 - 0.03 14.4 4.5 0.053 13.6 3.1 1.5 1 1 0 1 1 1 0 ATP synthase I chain Y_phosphatase2 PF03162.8 KNE00884.1 - 6.7e-49 165.4 0.0 8.1e-49 165.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 KNE00884.1 - 3.8e-06 27.2 0.0 5.8e-05 23.3 0.0 2.0 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 KNE00884.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain vWA-TerF-like PF10138.4 KNE00884.1 - 0.17 11.7 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 vWA found in TerF C terminus CRA PF06589.6 KNE00885.1 - 0.11 11.7 1.0 0.28 10.4 0.1 2.1 1 1 1 2 2 2 0 Circumsporozoite-related antigen (CRA) Glycophorin_A PF01102.13 KNE00885.1 - 0.48 10.1 5.1 0.5 10.1 1.1 2.2 2 0 0 2 2 2 0 Glycophorin A GSHPx PF00255.14 KNE00886.1 - 2.9e-45 152.0 0.0 3.6e-45 151.7 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 KNE00886.1 - 6.5e-08 32.2 0.1 1.7e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KNE00886.1 - 3.7e-07 29.7 0.0 2e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.1 KNE00886.1 - 0.055 13.5 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4174) Mst1_SARAH PF11629.3 KNE00886.1 - 0.43 10.4 1.9 1.5 8.7 0.5 2.1 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Pkinase PF00069.20 KNE00888.1 - 1e-49 169.0 0.0 1.4e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE00888.1 - 1.6e-31 109.3 0.1 5.8e-31 107.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KNE00888.1 - 7.7e-05 22.5 0.0 0.006 16.3 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KNE00888.1 - 0.014 14.3 0.0 0.11 11.3 0.0 2.1 2 0 0 2 2 2 0 Kinase-like IlvC PF01450.14 KNE00889.1 - 1.2e-47 161.5 0.0 1.8e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.7 KNE00889.1 - 6.6e-44 149.1 0.0 9.8e-44 148.6 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 KNE00889.1 - 0.072 12.9 0.0 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase GRAM PF02893.15 KNE00890.1 - 6.9e-18 63.9 0.0 1.3e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 GRAM domain bPH_3 PF14470.1 KNE00890.1 - 0.035 14.3 0.0 0.09 13.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial PH domain HrpB1_HrpK PF09613.5 KNE00892.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) APC_crr PF05923.7 KNE00892.1 - 0.38 10.4 3.2 4 7.2 0.5 2.6 2 0 0 2 2 2 0 APC cysteine-rich region AhpC-TSA PF00578.16 KNE00893.1 - 2.7e-36 123.9 0.0 3.6e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KNE00893.1 - 2.2e-14 53.2 0.0 2.6e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KNE00893.1 - 1.6e-12 46.8 0.1 2.7e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Ribosomal_L2_C PF03947.13 KNE00894.1 - 0.1 12.4 0.4 0.12 12.2 0.2 1.0 1 0 0 1 1 1 0 Ribosomal Proteins L2, C-terminal domain zf-DHHC PF01529.15 KNE00895.1 - 1.3e-35 122.3 2.3 2.3e-35 121.5 1.6 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Baculo_11_kDa PF06143.6 KNE00895.1 - 0.13 11.6 1.2 0.29 10.5 0.8 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family Proteasome PF00227.21 KNE00896.1 - 4e-53 179.5 0.0 4.7e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit CR6_interact PF10147.4 KNE00897.1 - 0.0094 15.2 3.3 0.0094 15.2 2.3 4.6 3 1 1 4 4 4 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 GAS PF13851.1 KNE00897.1 - 1.2 8.2 58.5 0.073 12.2 3.3 4.6 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding eIF2A PF08662.6 KNE00898.1 - 2.5e-40 138.2 1.6 1.2e-36 126.2 1.0 3.0 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 KNE00898.1 - 1.2e-05 24.8 0.0 3.2e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNE00898.1 - 0.00013 21.7 0.1 0.00079 19.2 0.1 2.4 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KNE00898.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 KNE00898.1 - 0.091 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) BolA PF01722.13 KNE00899.1 - 2.5e-17 62.5 0.0 3.3e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein Miro PF08477.8 KNE00900.1 - 2.9e-35 121.3 0.0 5.5e-17 62.3 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 KNE00900.1 - 1.5e-30 104.3 0.4 4.9e-30 102.6 0.2 1.9 2 0 0 2 2 2 1 EF hand associated EF_assoc_2 PF08356.7 KNE00900.1 - 1.8e-26 91.7 0.0 3.8e-26 90.6 0.0 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 KNE00900.1 - 7.6e-24 83.9 0.0 4.1e-12 45.7 0.0 3.2 2 1 0 2 2 2 2 Ras family EF-hand_1 PF00036.27 KNE00900.1 - 2.6e-09 35.7 5.9 0.00018 20.5 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KNE00900.1 - 7.7e-09 35.5 0.6 0.00079 19.5 0.1 3.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KNE00900.1 - 4.1e-08 32.4 4.8 0.005 16.6 0.0 3.3 3 0 0 3 3 2 2 EF-hand domain EF-hand_5 PF13202.1 KNE00900.1 - 5.5e-07 28.6 4.0 0.017 14.4 1.6 3.0 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KNE00900.1 - 3.1e-06 26.7 2.3 0.031 13.9 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair Arf PF00025.16 KNE00900.1 - 1.9e-05 23.9 0.0 0.29 10.3 0.0 3.5 3 1 0 3 3 3 2 ADP-ribosylation factor family AAA_14 PF13173.1 KNE00900.1 - 6e-05 22.9 0.3 0.041 13.7 0.2 3.3 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KNE00900.1 - 0.00042 20.2 0.0 0.24 11.3 0.0 3.0 2 2 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KNE00900.1 - 0.0043 16.4 0.0 0.55 9.6 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Arch_ATPase PF01637.13 KNE00900.1 - 0.0044 16.7 0.0 0.31 10.7 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase Dynamin_N PF00350.18 KNE00900.1 - 0.03 14.1 0.0 1.5 8.6 0.0 2.8 2 0 0 2 2 2 0 Dynamin family SRPRB PF09439.5 KNE00900.1 - 0.062 12.5 0.0 0.48 9.6 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Glyco_hydro_65m PF03632.10 KNE00900.1 - 0.064 11.9 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain Spore_GerQ PF09671.5 KNE00900.1 - 0.08 12.6 0.3 1.5 8.5 0.1 2.8 2 1 0 2 2 2 0 Spore coat protein (Spore_GerQ) EF-hand_4 PF12763.2 KNE00900.1 - 0.099 12.3 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand RRS1 PF04939.7 KNE00901.1 - 7.8e-66 220.5 7.0 9e-66 220.3 4.8 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) SWIB PF02201.13 KNE00904.1 - 1.5e-26 91.8 0.9 2.7e-26 91.0 0.6 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DUF3139 PF11337.3 KNE00904.1 - 0.034 14.4 0.4 0.17 12.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Glyco_hydro_57 PF03065.10 KNE00904.1 - 0.067 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 DUF4611 PF15387.1 KNE00904.1 - 0.49 10.5 8.1 0.049 13.7 2.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) Membr_traf_MHD PF10540.4 KNE00905.1 - 2.9e-12 46.5 0.6 1.1e-11 44.6 0.2 2.3 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 KNE00905.1 - 7.2e-07 28.9 0.6 2.9e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 C2 domain MutS_III PF05192.13 KNE00905.1 - 0.0024 17.6 0.9 0.0079 16.0 0.0 2.3 2 0 0 2 2 2 1 MutS domain III PAH PF02671.16 KNE00906.1 - 3.8e-48 160.8 6.3 1.7e-18 65.9 0.3 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 KNE00906.1 - 1.3e-42 143.6 0.1 4.2e-42 141.9 0.1 2.0 1 0 0 1 1 1 1 Sin3 family co-repressor Pkinase PF00069.20 KNE00907.1 - 2.2e-70 236.7 0.0 4e-70 235.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE00907.1 - 1.5e-36 125.7 0.0 3e-36 124.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 KNE00907.1 - 1.9e-28 98.1 3.5 3.5e-14 52.5 0.0 3.0 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.1 KNE00907.1 - 4.3e-10 39.0 0.0 7.6e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KNE00907.1 - 0.01 14.9 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GUN4 PF05419.7 KNE00907.1 - 0.041 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 GUN4-like APH PF01636.18 KNE00907.1 - 0.064 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RNase_H PF00075.19 KNE00908.1 - 4.8e-26 91.6 0.2 7.8e-26 90.9 0.1 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 KNE00908.1 - 9.4e-15 54.3 0.3 2e-14 53.3 0.2 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin Otopetrin PF03189.8 KNE00909.1 - 0.056 12.4 1.3 0.088 11.7 0.9 1.2 1 0 0 1 1 1 0 Otopetrin Topoisom_I_N PF02919.10 KNE00911.1 - 9.8e-100 332.2 0.1 9.8e-100 332.2 0.0 3.5 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 KNE00911.1 - 6.6e-84 280.6 5.0 6.6e-84 280.6 3.5 2.4 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 KNE00911.1 - 1.3e-30 104.8 0.7 1.3e-30 104.8 0.5 2.6 2 0 0 2 2 2 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 KNE00911.1 - 0.0091 15.1 0.4 0.11 11.7 0.0 2.4 2 0 0 2 2 2 1 RolB/RolC glucosidase family DUF2189 PF09955.4 KNE00912.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2189) SAPS PF04499.10 KNE00912.1 - 0.016 13.9 0.1 0.02 13.5 0.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Trypan_glycop_C PF10659.4 KNE00912.1 - 0.016 15.4 7.1 0.03 14.6 4.9 1.3 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain vMSA PF00695.14 KNE00912.1 - 0.079 12.1 0.2 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Herpes_gE PF02480.11 KNE00912.1 - 0.082 11.1 0.9 0.13 10.5 0.0 1.7 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E SIT PF15330.1 KNE00912.1 - 0.091 12.9 0.1 0.091 12.9 0.1 3.0 4 0 0 4 4 3 0 SHP2-interacting transmembrane adaptor protein, SIT Tim54 PF11711.3 KNE00912.1 - 0.099 11.2 3.4 0.14 10.6 2.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Gemini_mov PF01708.11 KNE00912.1 - 0.11 12.0 0.2 0.27 10.7 0.1 1.6 1 0 0 1 1 1 0 Geminivirus putative movement protein TMEM154 PF15102.1 KNE00912.1 - 0.12 12.0 7.4 19 4.9 5.2 2.4 1 1 0 1 1 1 0 TMEM154 protein family Adeno_E3_CR2 PF02439.10 KNE00912.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.15 KNE00912.1 - 0.2 11.3 0.2 0.38 10.4 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain DUF912 PF06024.7 KNE00912.1 - 0.46 10.5 8.2 1.7e+02 2.2 5.7 2.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Mucin PF01456.12 KNE00912.1 - 0.6 9.8 16.5 1 9.1 11.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2076 PF09849.4 KNE00915.1 - 6.7e-07 29.6 4.9 7.1e-07 29.5 3.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 KNE00915.1 - 0.00032 20.5 3.9 0.00064 19.5 2.7 1.5 1 0 0 1 1 1 1 CHCH domain Nucleoporin_FG PF13634.1 KNE00915.1 - 0.14 12.4 14.6 0.19 11.9 10.1 1.2 1 0 0 1 1 1 0 Nucleoporin FG repeat region Gly-zipper_OmpA PF13436.1 KNE00915.1 - 0.3 10.7 8.6 0.17 11.5 4.9 1.5 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Na_K-ATPase PF00287.13 KNE00915.1 - 0.86 8.3 3.9 1.1 7.9 2.7 1.1 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain PAT1 PF09770.4 KNE00915.1 - 0.87 7.7 5.3 0.91 7.6 3.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DnaJ PF00226.26 KNE00917.1 - 2.4e-15 55.9 5.7 4e-15 55.3 4.0 1.4 1 0 0 1 1 1 1 DnaJ domain Enkurin PF13864.1 KNE00917.1 - 0.039 14.1 1.0 0.11 12.6 0.6 1.7 2 0 0 2 2 2 0 Calmodulin-binding DUF2450 PF10475.4 KNE00917.1 - 0.086 11.7 0.4 0.13 11.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Ebp2 PF05890.7 KNE00917.1 - 0.14 11.3 3.6 0.2 10.9 2.5 1.1 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 Swi5 PF07061.6 KNE00917.1 - 0.2 11.4 1.8 0.38 10.5 1.2 1.4 1 0 0 1 1 1 0 Swi5 Complex1_49kDa PF00346.14 KNE00919.1 - 6.8e-128 425.3 0.0 8.5e-128 425.0 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 KNE00919.1 - 0.18 10.5 0.0 0.3 9.8 0.0 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase OB_NTP_bind PF07717.11 KNE00920.1 - 3.6e-18 65.4 0.0 9.5e-18 64.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KNE00920.1 - 6.6e-15 54.9 0.1 6.6e-15 54.9 0.0 2.3 3 0 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KNE00920.1 - 3.2e-14 52.5 0.0 9.5e-14 51.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.17 KNE00920.1 - 1.4e-07 31.3 0.1 4.7e-07 29.6 0.1 2.0 1 0 0 1 1 1 1 RWD domain DEAD PF00270.24 KNE00920.1 - 2.3e-07 30.4 0.3 4.5e-07 29.5 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KNE00920.1 - 0.00019 21.5 0.1 0.001 19.2 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KNE00920.1 - 0.00029 20.3 0.0 0.00066 19.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.1 KNE00920.1 - 0.0021 17.9 2.6 0.23 11.3 0.4 3.7 2 1 0 2 2 2 1 AAA domain UBA PF00627.26 KNE00920.1 - 0.0034 17.1 0.0 0.0085 15.9 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain KaiC PF06745.8 KNE00920.1 - 0.01 14.9 0.1 0.029 13.5 0.1 1.7 1 0 0 1 1 1 0 KaiC T2SE PF00437.15 KNE00920.1 - 0.011 14.6 0.0 0.022 13.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 KNE00920.1 - 0.041 13.6 0.0 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 KNE00920.1 - 0.048 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 KNE00920.1 - 0.095 12.6 0.0 0.31 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain OPT PF03169.10 KNE00922.1 - 9.7e-125 417.3 45.8 1.1e-124 417.1 31.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TFIID_20kDa PF03847.8 KNE00923.1 - 1.3e-29 102.2 0.1 2.2e-29 101.5 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Med15_fungi PF05397.7 KNE00923.1 - 0.0019 18.1 2.5 0.0055 16.6 1.7 1.8 1 0 0 1 1 1 1 Mediator complex subunit 15 V-SNARE PF05008.10 KNE00923.1 - 0.012 15.7 0.7 0.012 15.7 0.5 2.6 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF2156 PF09924.4 KNE00923.1 - 0.018 13.8 1.3 0.031 13.1 0.9 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2156) CBFD_NFYB_HMF PF00808.18 KNE00923.1 - 0.033 14.2 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF3135 PF11333.3 KNE00923.1 - 1.2 9.3 4.9 0.87 9.7 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) Cullin PF00888.17 KNE00924.1 - 2e-28 99.2 0.1 7.1e-28 97.4 0.0 1.8 2 0 0 2 2 2 1 Cullin family Cullin_binding PF03556.10 KNE00925.1 - 3.4e-28 98.1 3.8 4.4e-28 97.7 2.6 1.1 1 0 0 1 1 1 1 Cullin binding SBP_bac_8 PF13416.1 KNE00925.1 - 0.047 13.4 0.1 0.056 13.1 0.1 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein THAP PF05485.7 KNE00925.1 - 0.15 12.2 0.2 0.26 11.4 0.1 1.3 1 0 0 1 1 1 0 THAP domain HLH PF00010.21 KNE00926.1 - 5.8e-10 38.7 2.3 2.2e-09 36.8 1.6 2.1 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain AATase PF07247.7 KNE00927.1 - 5e-56 190.2 0.0 6.3e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 KNE00927.1 - 0.0088 14.9 0.0 0.016 14.0 0.0 1.4 1 0 0 1 1 1 1 Condensation domain NAD_binding_6 PF08030.7 KNE00927.1 - 0.09 12.6 0.0 8.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain SDA1 PF05285.7 KNE00930.1 - 0.94 8.6 6.8 1 8.5 4.7 1.0 1 0 0 1 1 1 0 SDA1 Zn_clus PF00172.13 KNE00931.1 - 3.4e-08 33.2 8.7 7.8e-08 32.1 6.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA_anti-codon PF01336.20 KNE00934.1 - 0.054 13.3 0.0 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain LCM PF04072.9 KNE00935.1 - 1.4e-21 76.8 0.0 2.6e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 KNE00935.1 - 6e-13 48.3 4.4 5.5e-08 32.4 0.3 5.5 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.1 KNE00935.1 - 1e-08 35.1 6.6 0.00032 20.7 0.2 4.8 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 KNE00935.1 - 1.2e-07 31.5 6.0 8.3e-06 25.7 0.2 4.9 4 1 1 5 5 5 1 Kelch motif Kelch_2 PF07646.10 KNE00935.1 - 1.5e-07 30.8 5.2 9.7e-07 28.3 0.4 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 KNE00935.1 - 0.00027 20.4 12.1 0.00089 18.7 0.1 5.4 7 0 0 7 7 7 1 Kelch motif Kelch_5 PF13854.1 KNE00935.1 - 0.0011 18.8 4.9 0.2 11.6 0.0 4.1 5 0 0 5 5 5 1 Kelch motif CBM_21 PF03370.8 KNE00938.1 - 6.9e-38 129.1 0.0 1.2e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit WD40 PF00400.27 KNE00939.1 - 2.6e-59 195.0 20.7 1.8e-11 43.4 1.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 KNE00939.1 - 3.4e-14 52.2 0.8 7.1e-14 51.2 0.6 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 KNE00939.1 - 1.1e-12 46.9 11.3 0.0032 15.6 0.0 5.9 2 2 3 5 5 5 4 Nucleoporin Nup120/160 F-box PF00646.28 KNE00939.1 - 7.1e-11 41.4 0.6 1.7e-10 40.2 0.4 1.7 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.1 KNE00939.1 - 3.9e-06 26.5 0.0 0.12 12.1 0.0 3.8 3 1 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 KNE00939.1 - 0.00047 19.9 0.7 0.95 9.1 0.1 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PRANC PF09372.5 KNE00939.1 - 0.0047 16.8 0.2 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 PRANC domain zf-ZPR1 PF03367.8 KNE00943.1 - 4e-117 386.9 2.7 1.4e-58 196.6 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Cytochrom_C_2 PF01322.15 KNE00943.1 - 0.0059 17.1 7.0 0.27 11.7 0.5 3.6 4 0 0 4 4 4 2 Cytochrome C' SpoIIIAH PF12685.2 KNE00943.1 - 0.019 14.4 0.4 0.019 14.4 0.3 1.6 2 0 0 2 2 2 0 SpoIIIAH-like protein Ion_trans PF00520.26 KNE00944.1 - 5.5e-101 335.8 99.2 1.7e-36 125.3 8.0 5.3 5 0 0 5 5 5 4 Ion transport protein EF-hand_1 PF00036.27 KNE00944.1 - 0.04 13.2 0.0 0.18 11.2 0.0 2.2 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 KNE00944.1 - 0.051 13.4 0.0 0.2 11.6 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain DEAD_2 PF06733.10 KNE00945.1 - 0.14 11.5 0.2 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 DEAD_2 MRP-S33 PF08293.6 KNE00946.1 - 7.6e-29 99.5 0.4 9.2e-29 99.2 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 YfhO PF09586.5 KNE00948.1 - 0.05 11.6 1.8 0.049 11.6 1.2 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO MIS13 PF08202.6 KNE00949.1 - 1.9e-43 148.6 0.3 3.3e-43 147.8 0.2 1.3 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Glyco_hydro_65m PF03632.10 KNE00950.1 - 2.8e-80 269.7 0.6 2e-79 266.9 0.4 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 KNE00950.1 - 1.7e-26 93.0 0.0 3.1e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain F5_F8_type_C PF00754.20 KNE00950.1 - 0.0027 17.5 1.0 0.06 13.1 0.1 3.0 3 0 0 3 3 3 1 F5/8 type C domain WD40 PF00400.27 KNE00951.1 - 9.9e-19 66.4 15.7 1.9e-05 24.3 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat SRA1 PF07304.6 KNE00951.1 - 4.7e-12 45.9 0.0 4.7e-12 45.9 0.0 3.4 4 1 1 5 5 5 1 Steroid receptor RNA activator (SRA1) Ribonuc_L-PSP PF01042.16 KNE00954.1 - 3.9e-11 42.7 0.0 4.1e-11 42.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Eclosion PF04736.7 KNE00954.1 - 0.03 13.7 0.0 0.031 13.7 0.0 1.1 1 0 0 1 1 1 0 Eclosion hormone RTA1 PF04479.8 KNE00958.1 - 2.2e-47 161.4 9.0 3.4e-47 160.8 6.3 1.2 1 0 0 1 1 1 1 RTA1 like protein RTA1 PF04479.8 KNE00960.1 - 1.5e-50 171.7 6.1 2.9e-50 170.8 4.2 1.3 1 0 0 1 1 1 1 RTA1 like protein zf-DHHC PF01529.15 KNE00960.1 - 0.74 9.1 7.9 7.4 5.9 0.2 2.8 2 1 0 2 2 2 0 DHHC palmitoyltransferase Cyclin PF08613.6 KNE00961.1 - 1.1e-37 129.7 0.5 1.8e-37 129.0 0.1 1.6 2 0 0 2 2 2 1 Cyclin DUF2457 PF10446.4 KNE00961.1 - 1.3 7.6 7.1 2 7.0 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2992 PF11208.3 KNE00962.1 - 0.018 14.9 0.3 0.021 14.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) zf-C2H2_jaz PF12171.3 KNE00963.1 - 0.029 14.4 1.3 0.033 14.3 0.1 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KNE00963.1 - 0.034 14.4 0.3 0.099 13.0 0.2 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KNE00963.1 - 0.058 13.7 1.4 11 6.4 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 KNE00963.1 - 0.064 13.6 0.3 0.15 12.4 0.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger EB1 PF03271.12 KNE00965.1 - 2.9e-13 49.6 0.4 7.9e-13 48.2 0.3 1.8 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 KNE00965.1 - 3.9e-07 30.0 0.5 6.7e-07 29.3 0.3 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain FliD_N PF02465.13 KNE00965.1 - 0.56 10.5 3.4 0.69 10.3 0.4 2.4 2 2 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus UQ_con PF00179.21 KNE00966.1 - 5.1e-38 129.6 0.4 8.1e-38 129.0 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KNE00966.1 - 0.09 12.6 0.5 0.39 10.6 0.1 2.3 2 0 0 2 2 2 0 RWD domain IATP PF04568.7 KNE00968.1 - 6e-12 45.4 6.3 6.6e-12 45.3 4.3 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP CASP_C PF08172.7 KNE00968.1 - 0.01 14.9 3.1 0.013 14.5 2.2 1.2 1 0 0 1 1 1 0 CASP C terminal Stathmin PF00836.14 KNE00968.1 - 0.015 14.9 3.5 0.015 14.8 2.4 1.1 1 0 0 1 1 1 0 Stathmin family RIC3 PF15361.1 KNE00968.1 - 0.057 13.6 1.1 0.065 13.4 0.8 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF1664 PF07889.7 KNE00968.1 - 0.059 13.1 1.3 0.06 13.1 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YtzH PF14165.1 KNE00968.1 - 0.1 12.8 0.2 0.11 12.7 0.1 1.1 1 0 0 1 1 1 0 YtzH-like protein DUF4640 PF15480.1 KNE00968.1 - 0.1 12.1 1.3 0.11 12.0 0.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4640) Fib_alpha PF08702.5 KNE00968.1 - 0.11 12.6 0.7 0.1 12.7 0.5 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Glutaredoxin2_C PF04399.8 KNE00968.1 - 0.16 11.5 1.3 0.17 11.4 0.9 1.1 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF1366 PF07104.6 KNE00968.1 - 0.43 10.2 4.4 0.45 10.1 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) Bap31 PF05529.7 KNE00968.1 - 0.5 9.8 4.5 0.5 9.8 3.1 1.0 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like U1snRNP70_N PF12220.3 KNE00968.1 - 0.53 10.6 5.1 0.57 10.5 3.5 1.1 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Ribosomal_S18 PF01084.15 KNE00970.1 - 1.7e-16 59.7 0.0 3.1e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 Metallophos PF00149.23 KNE00971.1 - 8.4e-42 142.8 0.3 1.1e-41 142.3 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KNE00971.1 - 0.0038 17.0 0.0 0.0069 16.2 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RRM_1 PF00076.17 KNE00972.1 - 1.4e-53 178.3 0.4 7.2e-15 54.3 0.0 5.6 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNE00972.1 - 1.1e-40 137.4 0.1 2.5e-11 43.3 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNE00972.1 - 1.4e-15 56.8 0.5 4.5e-06 26.4 0.0 5.0 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CENP-N PF05238.8 KNE00973.1 - 8.9e-104 347.7 0.2 1e-103 347.5 0.2 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like Vps16_N PF04841.8 KNE00974.1 - 3.3e-47 160.9 3.1 3.9e-45 154.1 0.1 3.6 2 1 0 2 2 2 1 Vps16, N-terminal region Vps16_C PF04840.7 KNE00974.1 - 5.4e-30 104.4 14.0 2.1e-29 102.4 8.0 2.7 2 1 0 2 2 2 1 Vps16, C-terminal region Skp1_POZ PF03931.10 KNE00975.1 - 6.9e-07 29.2 0.1 1.2e-06 28.4 0.1 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain CLTH PF10607.4 KNE00976.1 - 9.6e-12 44.8 0.1 2.1e-11 43.6 0.1 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 KNE00976.1 - 0.00073 19.2 2.1 0.011 15.3 0.2 2.5 2 0 0 2 2 2 1 RING-type zinc-finger AdoMet_MTase PF07757.8 KNE00978.1 - 1.7e-40 137.6 0.0 3.5e-40 136.6 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 KNE00978.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 KNE00979.1 - 1.2e-60 204.9 0.0 1.3e-60 204.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE00979.1 - 3.2e-26 91.9 0.0 4.1e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNE00979.1 - 0.00094 18.2 0.2 0.0014 17.6 0.1 1.5 1 1 0 1 1 1 1 Kinase-like DisA-linker PF10635.4 KNE00979.1 - 0.048 13.1 0.1 0.069 12.6 0.0 1.2 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region Seadorna_VP7 PF07387.6 KNE00979.1 - 0.054 12.3 0.1 0.085 11.6 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 ICL PF00463.16 KNE00981.1 - 2.6e-291 966.4 2.1 2.9e-291 966.2 1.4 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KNE00981.1 - 6.6e-12 45.1 0.0 1.5e-11 44.0 0.0 1.5 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase PQ-loop PF04193.9 KNE00984.1 - 2.2e-11 43.1 9.5 1.2e-07 31.1 1.8 3.8 4 1 0 4 4 4 2 PQ loop repeat ER_lumen_recept PF00810.13 KNE00984.1 - 0.08 13.4 11.5 0.069 13.6 4.7 2.8 1 1 1 2 2 2 0 ER lumen protein retaining receptor MtN3_slv PF03083.11 KNE00984.1 - 0.17 11.7 13.5 0.6 10.0 2.4 2.4 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange zf-C2H2 PF00096.21 KNE00986.1 - 3.9e-07 30.0 3.6 0.0048 17.1 1.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNE00986.1 - 1.8e-05 24.7 2.5 0.1 12.9 0.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger Cir_Bir_Yir PF06022.6 KNE00986.1 - 0.0014 17.9 0.3 0.0021 17.3 0.2 1.3 1 0 0 1 1 1 1 Plasmodium variant antigen protein Cir/Yir/Bir His_Phos_1 PF00300.17 KNE00987.1 - 4.5e-39 134.0 0.0 6.6e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3605 PF12239.3 KNE00990.1 - 1.3e-46 158.3 0.4 1.6e-46 158.0 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Histone PF00125.19 KNE00991.1 - 2.6e-15 56.2 0.2 3.2e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KNE00991.1 - 2.5e-05 24.3 0.1 3.3e-05 23.9 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KNE00991.1 - 2.6e-05 24.0 0.1 3.6e-05 23.6 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KNE00991.1 - 3.5e-05 23.7 0.1 5.9e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KNE00991.1 - 0.00041 19.7 0.0 0.00044 19.6 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 KNE00991.1 - 0.0026 17.4 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 KNE00991.1 - 0.057 13.7 0.1 0.11 12.8 0.1 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 KNE00991.1 - 0.12 12.1 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 KNE00993.1 - 9.8e-32 108.9 0.4 1.6e-31 108.2 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KNE00993.1 - 2e-06 27.9 0.0 3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KNE00993.1 - 0.006 16.6 0.6 0.0087 16.1 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KNE00993.1 - 0.056 13.1 0.1 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DUF3445 PF11927.3 KNE00994.1 - 4.5e-78 262.0 0.0 5.5e-78 261.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Mannosyl_trans2 PF04188.8 KNE00995.1 - 1.6e-52 178.8 32.5 4.7e-46 157.6 13.5 2.1 1 1 1 2 2 2 2 Mannosyltransferase (PIG-V)) AMP-binding PF00501.23 KNE00996.1 - 1.9e-93 313.1 0.0 2.6e-93 312.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KNE00996.1 - 2.3e-21 76.5 0.5 2.2e-20 73.3 0.1 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain HSP70 PF00012.15 KNE00998.1 - 2.9e-272 904.0 8.0 3.2e-272 903.8 5.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KNE00998.1 - 1.1e-17 63.6 0.0 1.6e-16 59.8 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KNE00998.1 - 0.0027 17.3 0.0 0.0061 16.1 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 KNE00998.1 - 0.0057 15.7 0.0 0.039 13.0 0.0 2.3 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase PMBR PF09373.5 KNE00998.1 - 0.4 10.7 0.0 0.4 10.7 0.0 2.8 4 0 0 4 4 4 0 Pseudomurein-binding repeat Ras PF00071.17 KNE00999.1 - 1.9e-42 144.4 0.0 2.2e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNE00999.1 - 5.1e-15 56.0 0.0 8.1e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNE00999.1 - 3.3e-06 26.4 0.0 4.7e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KNE00999.1 - 0.04 13.1 0.1 0.054 12.7 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KNE00999.1 - 0.045 13.2 0.1 0.1 12.0 0.1 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.20 KNE00999.1 - 0.077 12.4 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain UPF0121 PF03661.8 KNE01000.1 - 9.4e-20 70.8 4.3 1.2e-19 70.5 3.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DUF4395 PF14340.1 KNE01000.1 - 5.8 7.0 7.8 0.36 10.9 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4395) Septin PF00735.13 KNE01001.1 - 9.8e-112 372.5 0.2 9.8e-112 372.5 0.2 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KNE01001.1 - 6.8e-05 22.8 0.0 0.00019 21.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KNE01001.1 - 0.0015 18.6 3.0 0.0023 18.0 0.2 2.6 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KNE01001.1 - 0.0027 18.0 1.9 0.17 12.1 0.0 2.6 2 1 0 2 2 2 1 ABC transporter DUF258 PF03193.11 KNE01001.1 - 0.0031 16.7 0.1 0.0087 15.2 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KNE01001.1 - 0.0032 17.9 0.0 0.015 15.8 0.0 2.2 1 0 0 1 1 1 1 Miro-like protein Strep_SA_rep PF06696.6 KNE01001.1 - 0.0091 15.7 0.6 0.019 14.7 0.4 1.6 1 0 0 1 1 1 1 Streptococcal surface antigen repeat RNA_helicase PF00910.17 KNE01001.1 - 0.011 15.8 0.1 0.54 10.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_10 PF12846.2 KNE01001.1 - 0.02 14.3 0.6 0.099 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain AAA_5 PF07728.9 KNE01001.1 - 0.024 14.3 0.6 9.8 5.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) TRF PF08558.5 KNE01001.1 - 0.026 13.8 4.6 0.061 12.6 3.2 1.6 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) GTP_EFTU PF00009.22 KNE01001.1 - 0.037 13.4 1.2 0.36 10.2 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 KNE01001.1 - 0.047 13.6 1.7 0.12 12.3 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain DUF4559 PF15112.1 KNE01001.1 - 0.065 12.3 10.0 0.1 11.7 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF2937 PF11157.3 KNE01001.1 - 0.085 12.1 1.5 0.14 11.4 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) T2SE PF00437.15 KNE01001.1 - 0.29 9.9 3.6 0.48 9.2 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Phage_GPO PF05929.6 KNE01001.1 - 0.35 10.0 4.8 0.55 9.4 3.3 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Dynamin_N PF00350.18 KNE01001.1 - 0.73 9.6 0.0 0.73 9.6 0.0 2.5 2 1 0 2 2 2 0 Dynamin family Remorin_C PF03763.8 KNE01001.1 - 2 7.9 14.8 4.1 6.9 10.2 1.4 1 0 0 1 1 1 0 Remorin, C-terminal region AAA_24 PF13479.1 KNE01001.1 - 5.9 6.4 7.4 0.45 10.0 0.5 2.7 3 1 0 3 3 3 0 AAA domain CinA PF02464.12 KNE01002.1 - 1.4e-30 105.8 0.0 1.8e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 Competence-damaged protein Proteasom_Rpn13 PF04683.8 KNE01004.1 - 3.5e-23 81.4 0.0 4.6e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Pkinase PF00069.20 KNE01006.1 - 6.9e-55 185.9 0.0 9.9e-39 133.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNE01006.1 - 2.4e-23 82.5 0.0 2.1e-21 76.1 0.0 2.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNE01006.1 - 3e-06 26.4 0.0 0.0006 18.8 0.0 2.3 1 1 0 1 1 1 1 Kinase-like SpoVIF PF14069.1 KNE01006.1 - 0.05 13.3 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 Stage VI sporulation protein F ETRAMP PF09716.5 KNE01007.1 - 0.31 11.0 6.2 0.34 10.8 4.3 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF3899 PF13038.1 KNE01007.1 - 0.69 10.1 2.3 0.86 9.8 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) DUF843 PF05814.6 KNE01007.1 - 7.2 6.4 8.4 9.2 6.1 5.8 1.2 1 1 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) BLVR PF06375.6 KNE01007.1 - 8.9 6.1 12.5 9 6.1 8.7 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF3543 PF12063.3 KNE01008.1 - 9.9e-86 286.8 4.0 1.5e-85 286.2 2.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 KNE01008.1 - 1.6e-65 220.8 0.0 3.1e-65 219.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE01008.1 - 1.7e-43 148.6 0.0 2.6e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNE01008.1 - 7e-06 25.2 0.0 0.039 12.9 0.0 3.1 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 KNE01008.1 - 0.11 12.2 0.1 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1162 PF06650.7 KNE01011.1 - 2.8e-78 262.9 0.5 6.4e-75 251.9 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 KNE01011.1 - 3.1e-43 146.0 0.6 3.1e-43 146.0 0.4 2.7 3 0 0 3 3 3 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 KNE01011.1 - 0.00084 19.4 0.0 0.0027 17.8 0.0 1.8 1 0 0 1 1 1 1 ATG C terminal domain Formyl_trans_N PF00551.14 KNE01012.1 - 9.1e-30 103.5 0.0 1.6e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 KNE01012.1 - 3.4e-06 27.0 0.0 6.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain MFS_1 PF07690.11 KNE01014.1 - 6.3e-06 25.1 28.4 0.00024 19.9 5.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF21 PF01595.15 KNE01014.1 - 9.5 5.4 6.9 4.4 6.5 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF21 PCI_Csn8 PF10075.4 KNE01015.1 - 1.9e-06 27.6 0.2 3.2e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Ran-binding PF05508.6 KNE01016.1 - 3.3e-05 22.9 0.3 4e-05 22.6 0.2 1.0 1 0 0 1 1 1 1 RanGTP-binding protein zf-C4H2 PF10146.4 KNE01016.1 - 0.0089 16.0 0.1 0.011 15.8 0.1 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein Hrs_helical PF12210.3 KNE01016.1 - 0.044 14.0 0.7 0.17 12.1 0.4 1.9 2 1 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF713 PF05218.9 KNE01016.1 - 0.048 13.3 0.2 0.055 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF713) DUF972 PF06156.8 KNE01016.1 - 0.13 12.6 0.4 0.15 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Trp_syntA PF00290.15 KNE01017.1 - 9e-91 302.9 0.2 1.5e-90 302.2 0.2 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 KNE01017.1 - 2.8e-46 158.1 0.7 4.5e-46 157.4 0.5 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rrn6 PF10214.4 KNE01018.1 - 2.1e-66 224.5 21.9 8.4e-66 222.5 15.2 1.7 1 1 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor DUF2958 PF11171.3 KNE01018.1 - 0.067 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2958) Glyco_hydro_63 PF03200.11 KNE01019.1 - 6.2e-247 821.4 3.6 5.2e-246 818.3 2.5 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 KNE01019.1 - 2.8e-05 22.9 1.3 5e-05 22.1 0.9 1.3 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 KNE01019.1 - 0.03 13.0 0.6 0.087 11.5 0.1 2.0 2 1 0 2 2 2 0 Amylo-alpha-1,6-glucosidase CLTH PF10607.4 KNE01020.1 - 6.9e-28 97.1 4.4 1.6e-27 95.9 3.1 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KNE01020.1 - 0.0014 18.3 0.0 0.0029 17.3 0.0 1.6 1 0 0 1 1 1 1 LisH LAMTOR PF15454.1 KNE01023.1 - 2.5e-10 40.4 7.1 4.3e-10 39.7 4.6 1.7 1 1 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator LRR_4 PF12799.2 KNE01024.1 - 1.7e-08 33.8 29.0 0.00061 19.3 7.6 5.1 2 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KNE01024.1 - 6.5e-08 32.2 27.8 0.0004 20.0 10.0 4.5 1 1 3 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 KNE01024.1 - 6.5e-07 28.5 23.3 0.078 13.0 0.3 6.7 5 1 1 6 6 6 4 Leucine Rich Repeat LRR_6 PF13516.1 KNE01024.1 - 6.5e-06 25.6 27.9 0.0003 20.5 0.7 5.6 4 1 1 5 5 5 3 Leucine Rich repeat LRR_7 PF13504.1 KNE01024.1 - 0.85 10.0 20.8 0.93 9.9 0.2 6.1 5 1 0 5 5 5 0 Leucine rich repeat AMMECR1 PF01871.12 KNE01025.1 - 7.4e-43 145.6 0.0 9.4e-43 145.2 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 Zip PF02535.17 KNE01026.1 - 2.7e-53 181.0 6.4 3.2e-53 180.8 4.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter UCH PF00443.24 KNE01027.1 - 3e-61 206.8 0.0 1.1e-60 205.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KNE01027.1 - 9e-25 87.7 0.8 2.2e-17 63.4 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PMSR PF01625.16 KNE01028.1 - 3.3e-52 176.5 0.1 3.8e-52 176.2 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Rep_fac_C PF08542.6 KNE01029.1 - 3e-19 68.7 0.3 1.2e-18 66.8 0.1 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KNE01029.1 - 2.4e-10 40.2 0.2 5.1e-10 39.2 0.1 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KNE01029.1 - 1.3e-06 28.6 0.6 5.1e-06 26.7 0.4 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KNE01029.1 - 2.9e-06 26.2 0.4 7.7e-06 24.8 0.1 1.7 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KNE01029.1 - 0.00014 22.0 0.4 0.00079 19.5 0.1 2.4 2 2 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 KNE01029.1 - 0.022 14.7 0.1 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 KNE01029.1 - 0.026 13.6 0.0 0.16 11.0 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI T2SE PF00437.15 KNE01029.1 - 0.027 13.3 0.0 0.055 12.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DNA_pol3_delta PF06144.8 KNE01029.1 - 0.047 13.2 0.0 0.11 11.9 0.0 1.7 1 1 0 1 1 1 0 DNA polymerase III, delta subunit AAA_16 PF13191.1 KNE01029.1 - 0.07 13.1 3.6 0.66 9.9 0.0 3.1 2 2 1 3 3 3 0 AAA ATPase domain Pmp3 PF01679.12 KNE01030.1 - 0.16 11.7 12.5 0.76 9.5 3.7 2.3 1 1 1 2 2 2 0 Proteolipid membrane potential modulator Pmp3 PF01679.12 KNE01031.1 - 4.5e-08 32.6 8.6 7.4e-08 31.9 6.0 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Herpes_UL20 PF04544.7 KNE01031.1 - 0.12 12.2 2.6 0.15 11.9 1.8 1.1 1 0 0 1 1 1 0 Herpesvirus egress protein UL20 Ribosomal_60s PF00428.14 KNE01031.1 - 2.4 8.6 7.0 4.2 7.8 4.8 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Snf7 PF03357.16 KNE01032.1 - 3.1e-25 88.5 20.0 3.1e-25 88.5 13.9 1.2 1 1 0 1 1 1 1 Snf7 SKI PF01202.17 KNE01032.1 - 0.016 15.1 0.7 0.016 15.1 0.5 2.0 2 1 0 2 2 2 0 Shikimate kinase Eno-Rase_FAD_bd PF07055.7 KNE01032.1 - 0.04 13.8 1.6 0.14 12.0 1.1 1.9 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain Methyltransf_5 PF01795.14 KNE01032.1 - 0.075 12.3 3.6 0.099 11.9 2.5 1.3 1 0 0 1 1 1 0 MraW methylase family HTH_40 PF14493.1 KNE01032.1 - 0.82 9.9 4.5 0.31 11.3 0.4 2.3 2 2 0 2 2 2 0 Helix-turn-helix domain DUF4172 PF13776.1 KNE01032.1 - 1.8 8.6 6.2 19 5.4 0.3 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4172) zf-C4H2 PF10146.4 KNE01032.1 - 3.4 7.6 13.1 2 8.3 7.0 1.8 1 1 1 2 2 2 0 Zinc finger-containing protein DUF4611 PF15387.1 KNE01033.1 - 0.093 12.8 0.6 0.093 12.8 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) YL1 PF05764.8 KNE01033.1 - 0.19 11.3 5.6 0.28 10.7 3.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein INTS5_C PF14838.1 KNE01034.1 - 0.0015 16.9 0.2 0.002 16.5 0.1 1.1 1 0 0 1 1 1 1 Integrator complex subunit 5 C-terminus NESP55 PF06390.7 KNE01034.1 - 0.21 10.9 8.1 0.27 10.5 5.6 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Trypan_PARP PF05887.6 KNE01034.1 - 0.98 9.2 5.9 1.7 8.4 4.1 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) BLOC1_2 PF10046.4 KNE01035.1 - 1.8e-18 66.4 8.3 2e-18 66.3 5.8 1.0 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.7 KNE01035.1 - 0.033 13.9 4.0 0.051 13.3 2.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1024 PF06260.7 KNE01035.1 - 0.056 13.5 1.1 0.08 13.0 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1024) HAUS5 PF14817.1 KNE01035.1 - 0.076 11.5 3.2 0.084 11.4 2.2 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 CENP-F_leu_zip PF10473.4 KNE01035.1 - 0.23 11.3 9.7 0.29 10.9 6.7 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 KNE01035.1 - 0.38 10.3 4.2 0.41 10.2 2.9 1.2 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 KNE01035.1 - 0.8 8.0 4.9 0.82 8.0 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) NPV_P10 PF05531.7 KNE01035.1 - 1.3 9.3 5.5 16 5.8 3.9 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Ribosomal_L16 PF00252.13 KNE01036.1 - 2.2e-31 108.3 0.5 3.2e-31 107.8 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e 5-FTHF_cyc-lig PF01812.15 KNE01036.1 - 0.093 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family tRNA-synt_2d PF01409.15 KNE01037.1 - 7.8e-52 175.9 0.2 5.3e-26 91.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 KNE01037.1 - 1.4e-21 76.4 0.1 3.6e-21 75.1 0.0 1.8 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.15 KNE01037.1 - 0.046 12.4 1.3 0.72 8.5 0.1 2.5 3 0 0 3 3 3 0 tRNA synthetases class II (D, K and N) Flavodoxin_1 PF00258.20 KNE01038.1 - 7.6e-26 90.8 0.0 2.4e-25 89.2 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.15 KNE01038.1 - 8.3e-24 84.2 0.0 1.3e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KNE01038.1 - 4.5e-14 52.9 0.0 8.3e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KNE01038.1 - 0.005 16.8 0.0 0.014 15.4 0.0 1.7 1 1 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.2 KNE01038.1 - 0.21 11.0 0.0 0.75 9.1 0.0 1.9 2 0 0 2 2 2 0 Flavodoxin domain Bromodomain PF00439.20 KNE01039.1 - 1.8e-36 123.9 3.2 2e-18 66.0 0.1 2.6 2 0 0 2 2 2 2 Bromodomain TrmE_N PF10396.4 KNE01040.1 - 3.7e-37 126.7 0.0 6.5e-37 125.9 0.0 1.4 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 KNE01040.1 - 7.2e-16 58.1 0.3 2.5e-15 56.4 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTPase_Cys_C PF12631.2 KNE01040.1 - 1.7e-13 50.7 0.0 4.7e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE FeoB_N PF02421.13 KNE01040.1 - 1.6e-07 30.7 0.1 2.6e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KNE01040.1 - 0.00091 18.7 0.0 0.023 14.1 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KNE01040.1 - 0.0012 18.7 0.2 0.078 12.7 0.0 3.0 2 1 1 3 3 3 1 Dynamin family Miro PF08477.8 KNE01040.1 - 0.025 15.0 0.0 0.089 13.2 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein DUF2443 PF10398.4 KNE01040.1 - 0.051 13.3 0.6 0.15 11.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) DUF258 PF03193.11 KNE01040.1 - 0.069 12.3 0.0 0.27 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 KNE01040.1 - 0.11 12.0 0.0 15 5.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ParA PF10609.4 KNE01041.1 - 1.5e-35 120.9 0.2 3e-35 119.9 0.1 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KNE01041.1 - 1.5e-12 47.3 0.0 2.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 KNE01041.1 - 1.2e-07 31.0 0.0 1.8e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 KNE01041.1 - 9.2e-07 28.9 0.1 4.8e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 KNE01041.1 - 0.00011 21.3 2.8 0.00084 18.4 1.2 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.13 KNE01041.1 - 0.00021 20.5 0.3 0.046 12.8 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family APS_kinase PF01583.15 KNE01041.1 - 0.083 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_19 PF13245.1 KNE01041.1 - 0.12 12.1 1.0 14 5.4 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_25 PF13481.1 KNE01041.1 - 0.14 11.5 0.0 0.34 10.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain CTP_transf_1 PF01148.15 KNE01044.1 - 2.4e-20 73.2 12.2 2.6e-17 63.3 5.9 2.2 1 1 1 2 2 2 2 Cytidylyltransferase family ABC_membrane PF00664.18 KNE01046.1 - 7.8e-60 202.6 35.9 2.2e-32 112.6 15.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KNE01046.1 - 2.4e-49 167.1 0.8 8.5e-30 103.8 0.1 3.3 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KNE01046.1 - 4.2e-09 35.9 8.3 1.8e-05 24.1 0.7 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KNE01046.1 - 1e-07 32.2 10.2 0.00018 21.5 0.3 5.1 3 2 1 4 4 4 1 AAA domain AAA_29 PF13555.1 KNE01046.1 - 6.9e-07 28.7 1.4 0.015 14.8 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KNE01046.1 - 7.6e-07 29.9 0.1 0.014 16.2 0.0 3.1 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KNE01046.1 - 4.2e-06 26.0 0.5 0.0066 15.6 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KNE01046.1 - 4e-05 23.5 0.2 0.33 10.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 KNE01046.1 - 5.3e-05 23.6 0.2 0.17 12.3 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 KNE01046.1 - 0.00023 21.1 0.1 0.045 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KNE01046.1 - 0.00032 20.9 4.0 0.22 11.8 0.0 4.0 4 0 0 4 4 4 1 AAA domain T2SE PF00437.15 KNE01046.1 - 0.00079 18.4 0.6 0.11 11.3 0.3 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 KNE01046.1 - 0.0008 19.5 1.4 2.7 8.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KNE01046.1 - 0.0016 17.5 0.0 0.65 9.0 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.1 KNE01046.1 - 0.003 17.1 0.2 0.51 9.8 0.0 2.7 3 0 0 3 3 2 1 AAA domain cobW PF02492.14 KNE01046.1 - 0.0063 15.9 0.7 0.051 13.0 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 KNE01046.1 - 0.0089 16.2 0.1 1.5 9.0 0.0 3.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 KNE01046.1 - 0.011 15.2 0.1 6.4 6.2 0.0 3.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 KNE01046.1 - 0.02 14.3 0.2 2.2 7.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 KNE01046.1 - 0.02 14.7 1.7 2.9 7.8 0.0 3.7 3 0 0 3 3 3 0 AAA domain Vps51 PF08700.6 KNE01046.1 - 0.04 13.7 1.9 0.079 12.8 0.2 2.3 2 0 0 2 2 2 0 Vps51/Vps67 FtsK_SpoIIIE PF01580.13 KNE01046.1 - 0.067 12.6 0.3 2.9 7.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.12 KNE01046.1 - 0.074 12.4 0.2 8.5 5.7 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Dynamin_N PF00350.18 KNE01046.1 - 0.29 10.9 5.5 1.5 8.5 0.1 3.1 3 0 0 3 3 2 0 Dynamin family AAA_23 PF13476.1 KNE01046.1 - 1.7 8.9 29.0 0.48 10.7 1.5 4.7 4 2 0 4 4 3 0 AAA domain PHD PF00628.24 KNE01048.1 - 9e-08 31.7 12.7 1.7e-07 30.7 8.8 1.5 1 0 0 1 1 1 1 PHD-finger Pam16 PF03656.8 KNE01049.1 - 3.2e-33 114.2 2.2 3.6e-33 114.0 1.5 1.0 1 0 0 1 1 1 1 Pam16 5_nucleotid_C PF02872.13 KNE01049.1 - 0.051 13.5 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain DUF4046 PF13255.1 KNE01050.1 - 0.0045 15.7 0.0 0.012 14.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4046) PA26 PF04636.8 KNE01050.1 - 1.1 7.8 5.5 1.8 7.1 3.8 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) IBR PF01485.16 KNE01051.1 - 6.3e-18 64.4 40.0 1.3e-09 37.7 1.3 4.0 3 1 0 3 3 3 2 IBR domain zf-C3HC4_2 PF13923.1 KNE01051.1 - 0.0063 16.5 10.5 0.0063 16.5 7.3 5.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KNE01051.1 - 0.011 15.3 8.5 0.011 15.3 5.9 5.3 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Sporozoite_P67 PF05642.6 KNE01053.1 - 0.22 9.3 0.6 0.27 9.0 0.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen UNC-50 PF05216.8 KNE01054.1 - 4.9e-85 284.4 17.1 6.2e-85 284.0 11.8 1.0 1 0 0 1 1 1 1 UNC-50 family DUF3808 PF10300.4 KNE01055.1 - 6.1e-122 407.5 1.0 7.9e-122 407.1 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_16 PF13432.1 KNE01055.1 - 0.016 15.9 1.0 1.6 9.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 KNE01055.1 - 0.081 12.5 6.8 0.25 10.9 0.1 4.1 5 0 0 5 5 5 0 TPR repeat TPR_2 PF07719.12 KNE01055.1 - 0.15 12.0 3.8 3.8 7.6 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L4 PF00573.17 KNE01061.1 - 8.1e-46 155.8 2.5 1.3e-45 155.1 1.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 KNE01061.1 - 3.2e-29 100.6 5.4 6.3e-27 93.2 1.7 2.6 2 0 0 2 2 2 2 60S ribosomal protein L4 C-terminal domain Pro_isomerase PF00160.16 KNE01062.1 - 3.4e-30 105.3 0.2 1e-29 103.7 0.1 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 KNE01062.1 - 4.7e-12 45.3 10.2 3.4e-08 33.0 0.4 2.9 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 KNE01062.1 - 7.1e-07 28.6 3.4 0.0039 17.0 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KNE01062.1 - 1.6e-06 27.4 1.1 0.0031 17.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 KNE01062.1 - 0.00016 21.5 0.5 0.0031 17.4 0.3 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KNE01062.1 - 0.0076 16.8 3.4 0.011 16.4 0.5 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KNE01062.1 - 0.042 14.4 0.2 0.68 10.7 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KNE01062.1 - 0.058 13.2 0.0 0.058 13.2 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KNE01062.1 - 0.061 13.2 3.0 0.098 12.5 0.4 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 KNE01062.1 - 0.092 12.6 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TraE PF05309.6 KNE01062.1 - 0.096 11.8 0.0 0.66 9.0 0.0 2.2 2 0 0 2 2 2 0 TraE protein TPR_19 PF14559.1 KNE01062.1 - 0.27 11.6 2.7 1.1 9.6 0.5 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat SQS_PSY PF00494.14 KNE01063.1 - 1.3e-18 67.2 0.0 2.1e-18 66.5 0.0 1.3 1 1 0 1 1 1 1 Squalene/phytoene synthase EMG1 PF03587.9 KNE01063.1 - 0.052 12.8 0.1 0.091 12.0 0.1 1.4 1 0 0 1 1 1 0 EMG1/NEP1 methyltransferase Sec7 PF01369.15 KNE01064.1 - 2.2e-63 213.3 0.4 5.1e-63 212.1 0.3 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KNE01064.1 - 4.7e-13 48.9 1.9 4.7e-13 48.9 1.3 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal OMPdecase PF00215.19 KNE01065.1 - 1.3e-77 260.2 0.0 1.5e-77 260.0 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Mito_carr PF00153.22 KNE01066.1 - 1e-14 53.9 1.7 1.4e-08 34.2 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Vps26 PF03643.10 KNE01068.1 - 1.1e-109 365.4 1.2 1.3e-109 365.2 0.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KNE01068.1 - 0.0019 18.0 0.2 0.81 9.4 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain COX3 PF00510.13 KNE01068.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit III Gp_dh_C PF02800.15 KNE01069.1 - 9.1e-73 242.8 0.0 1.3e-72 242.3 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KNE01069.1 - 1e-59 200.8 1.3 1.3e-59 200.5 0.1 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF2436 PF10365.4 KNE01069.1 - 0.0015 18.1 0.2 0.0028 17.3 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2436) DapB_N PF01113.15 KNE01069.1 - 0.013 15.4 0.8 0.06 13.2 0.2 2.5 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 KNE01069.1 - 0.031 13.4 0.0 0.069 12.2 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RasGEF PF00617.14 KNE01071.1 - 2.7e-59 200.0 2.5 7.4e-59 198.6 1.7 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KNE01071.1 - 2.3e-20 72.6 0.7 1.2e-19 70.3 0.0 2.5 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.23 KNE01071.1 - 6.7e-15 54.2 0.0 1.5e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KNE01071.1 - 7.4e-11 41.4 0.1 1.6e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KNE01071.1 - 9.6e-07 28.2 0.0 2.8e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain GRIP PF01465.15 KNE01072.1 - 8.7e-15 53.9 0.2 2.9e-14 52.2 0.2 2.0 1 0 0 1 1 1 1 GRIP domain Uds1 PF15456.1 KNE01072.1 - 0.00019 21.4 10.6 0.00019 21.4 7.4 9.1 3 2 5 8 8 8 2 Up-regulated During Septation FliJ PF02050.11 KNE01072.1 - 0.00043 20.3 12.5 0.00043 20.3 8.7 10.2 3 2 7 10 10 10 3 Flagellar FliJ protein SlyX PF04102.7 KNE01072.1 - 0.0015 18.8 2.9 0.0015 18.8 2.0 12.8 7 4 7 14 14 14 4 SlyX Filament PF00038.16 KNE01072.1 - 0.0019 17.6 35.6 0.0019 17.6 24.7 6.8 1 1 4 5 5 5 2 Intermediate filament protein Reo_sigmaC PF04582.7 KNE01072.1 - 0.0041 16.3 64.2 0.041 13.0 9.4 6.9 2 2 4 7 7 7 5 Reovirus sigma C capsid protein THOC7 PF05615.8 KNE01072.1 - 0.0076 16.5 10.8 0.0076 16.5 7.5 8.7 1 1 4 6 6 6 2 Tho complex subunit 7 DUF948 PF06103.6 KNE01072.1 - 0.098 12.5 63.6 0.25 11.2 0.2 9.7 6 5 2 8 8 8 0 Bacterial protein of unknown function (DUF948) Myosin_tail_1 PF01576.14 KNE01072.1 - 0.13 9.9 167.2 0.13 9.9 38.9 4.1 1 1 2 3 3 3 0 Myosin tail TYW3 PF02676.9 KNE01073.1 - 2.6e-67 225.9 0.0 3.4e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 zf-RING_2 PF13639.1 KNE01074.1 - 4.4e-10 39.2 12.5 5.5e-10 38.9 2.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KNE01074.1 - 2.4e-06 27.5 12.4 0.00028 20.9 8.6 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KNE01074.1 - 1.3e-05 25.0 12.5 1.6e-05 24.8 2.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KNE01074.1 - 2.4e-05 23.9 1.0 2.4e-05 23.9 0.7 3.0 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 KNE01074.1 - 0.00012 21.7 9.6 0.00021 20.8 1.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KNE01074.1 - 0.00013 21.5 10.4 0.00022 20.8 1.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNE01074.1 - 0.00028 20.5 8.9 0.00039 20.0 1.2 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KNE01074.1 - 0.00048 19.9 2.2 0.00048 19.9 1.5 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 KNE01074.1 - 0.0045 16.7 4.9 0.031 14.0 0.6 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.10 KNE01074.1 - 0.075 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 U-box domain Prok-RING_4 PF14447.1 KNE01074.1 - 0.078 12.5 1.0 0.2 11.2 0.7 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.3 KNE01074.1 - 0.96 9.4 10.1 1.1e+03 -0.4 7.0 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain HMG_box_2 PF09011.5 KNE01076.1 - 0.072 13.4 0.1 0.094 13.0 0.1 1.1 1 0 0 1 1 1 0 HMG-box domain MerE PF05052.7 KNE01080.1 - 1.5 8.8 3.9 6.1 6.9 2.7 1.9 1 1 0 1 1 1 0 MerE protein Complex1_30kDa PF00329.14 KNE01083.1 - 2e-36 124.3 0.0 3.8e-36 123.4 0.0 1.5 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit End3 PF12761.2 KNE01084.1 - 9.6e-73 243.9 5.9 1.3e-72 243.5 4.1 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 KNE01084.1 - 1.3e-55 185.5 0.1 1.5e-54 182.1 0.1 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 KNE01084.1 - 7e-05 21.8 1.5 0.00022 20.3 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KNE01084.1 - 0.00019 20.9 0.1 0.00044 19.8 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 KNE01084.1 - 0.00053 20.0 0.1 0.0039 17.2 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KNE01084.1 - 0.053 12.8 0.4 0.29 10.5 0.1 2.4 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 KNE01084.1 - 0.061 13.2 0.9 0.46 10.5 0.2 2.8 3 0 0 3 3 3 0 EF-hand domain IncA PF04156.9 KNE01084.1 - 0.17 11.4 6.2 0.24 10.9 4.3 1.2 1 0 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 KNE01084.1 - 0.25 11.4 3.7 0.42 10.7 2.6 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 KNE01084.1 - 0.57 9.9 2.4 1.1 9.0 1.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlxA PF14282.1 KNE01084.1 - 0.84 9.6 6.8 1.9 8.4 4.7 1.6 1 0 0 1 1 1 0 FlxA-like protein Sigma70_ner PF04546.8 KNE01084.1 - 1.2 8.7 7.1 0.23 11.0 2.2 1.8 3 0 0 3 3 3 0 Sigma-70, non-essential region WD40 PF00400.27 KNE01085.1 - 1.1e-12 47.2 10.6 6.6e-06 25.8 0.3 5.7 5 1 1 6 6 6 3 WD domain, G-beta repeat Kelch_5 PF13854.1 KNE01085.1 - 0.35 10.8 1.5 11 6.0 0.0 2.8 3 0 0 3 3 3 0 Kelch motif NMT PF01233.14 KNE01088.1 - 2e-77 258.3 0.0 3.2e-77 257.6 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 KNE01088.1 - 1.5e-76 256.0 0.3 2.9e-76 255.1 0.2 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 KNE01088.1 - 0.00072 19.4 0.0 0.028 14.2 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain F-box-like PF12937.2 KNE01089.1 - 1.8e-06 27.5 0.1 4e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like Kunitz_legume PF00197.13 KNE01089.1 - 0.017 14.6 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Trypsin and protease inhibitor eIF-3c_N PF05470.7 KNE01091.1 - 4.7e-140 467.5 25.0 4.3e-112 375.1 2.0 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 KNE01091.1 - 6.2e-08 32.9 0.3 6.2e-08 32.9 0.2 3.2 3 0 0 3 3 3 1 PCI domain FeoC PF09012.5 KNE01091.1 - 0.025 14.2 0.0 0.07 12.8 0.0 1.7 1 0 0 1 1 1 0 FeoC like transcriptional regulator TPR_14 PF13428.1 KNE01091.1 - 0.18 12.5 0.7 2.8 8.8 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ATP_bind_3 PF01171.15 KNE01092.1 - 1.9e-18 66.6 0.0 3.3e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 KNE01092.1 - 0.001 19.3 0.0 0.0025 18.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 KNE01092.1 - 0.033 12.7 0.1 0.061 11.8 0.0 1.4 1 1 0 1 1 1 0 tRNA methyl transferase DUF2616 PF11077.3 KNE01092.1 - 0.24 10.9 5.9 1.4 8.4 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) adh_short PF00106.20 KNE01093.1 - 2e-32 112.4 0.0 2.7e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNE01093.1 - 1e-13 51.6 0.1 1.3e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KNE01093.1 - 6.7e-11 42.1 0.0 9.9e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KNE01093.1 - 0.00026 20.6 0.2 0.00056 19.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KNE01093.1 - 0.00059 19.3 0.1 0.0013 18.2 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KNE01093.1 - 0.01 14.7 0.1 0.023 13.5 0.1 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 KNE01093.1 - 0.015 14.2 0.1 0.065 12.1 0.0 1.7 1 1 0 2 2 2 0 Saccharopine dehydrogenase DUF1776 PF08643.5 KNE01093.1 - 0.046 12.8 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KNE01093.1 - 0.07 13.1 0.8 0.18 11.8 0.6 1.8 1 1 0 1 1 1 0 NADH(P)-binding Shikimate_DH PF01488.15 KNE01093.1 - 0.1 12.7 1.8 0.17 11.9 0.3 2.0 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase CBM_21 PF03370.8 KNE01094.1 - 4.9e-25 87.7 3.9 9.6e-25 86.7 2.7 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Glyco_transf_21 PF13506.1 KNE01094.1 - 0.056 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 CBM_25 PF03423.8 KNE01094.1 - 0.086 12.9 0.9 0.22 11.6 0.7 1.7 1 1 0 1 1 1 0 Carbohydrate binding domain (family 25) DrsE PF02635.10 KNE01095.1 - 0.055 13.5 0.0 0.056 13.4 0.0 1.1 1 0 0 1 1 1 0 DsrE/DsrF-like family Rubis-subs-bind PF09273.6 KNE01097.1 - 0.073 12.9 0.0 0.073 12.9 0.0 1.0 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding tRNA-synt_1c PF00749.16 KNE01099.1 - 2.8e-108 361.2 0.0 1.1e-107 359.3 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 KNE01099.1 - 2e-47 160.7 2.9 3.2e-47 160.1 2.0 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 KNE01099.1 - 2.8e-30 105.2 1.2 6.3e-29 100.8 0.1 2.8 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 KNE01099.1 - 3.5e-20 72.4 6.1 3.5e-20 72.4 4.2 2.0 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Abhydrolase_6 PF12697.2 KNE01101.1 - 1.3e-28 100.4 0.0 2.3e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNE01101.1 - 4.9e-23 81.8 0.0 8.4e-23 81.1 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNE01101.1 - 2.8e-12 46.6 0.0 5.5e-10 39.1 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KNE01101.1 - 0.00039 20.2 0.0 0.002 17.9 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase DUF2305 PF10230.4 KNE01101.1 - 0.00055 19.4 0.0 0.008 15.6 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_3 PF07859.8 KNE01101.1 - 0.0033 17.0 0.0 0.0069 15.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KNE01101.1 - 0.0064 16.7 0.0 0.027 14.7 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain DUF915 PF06028.6 KNE01101.1 - 0.035 13.2 0.0 0.086 11.9 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Plus-3 PF03126.13 KNE01102.1 - 3.5e-29 101.0 0.6 1.3e-28 99.1 0.4 2.0 1 0 0 1 1 1 1 Plus-3 domain RRXRR PF14239.1 KNE01104.1 - 0.068 12.5 0.6 0.065 12.6 0.4 1.1 1 0 0 1 1 1 0 RRXRR protein DUF1129 PF06570.6 KNE01104.1 - 0.13 11.5 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) ACBP PF00887.14 KNE01107.1 - 1.1e-11 44.2 0.6 1.1e-11 44.2 0.4 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.13 KNE01107.1 - 0.066 13.3 0.1 0.078 13.1 0.1 1.1 1 0 0 1 1 1 0 FERM central domain DUF2781 PF10914.3 KNE01108.1 - 6.4e-38 129.8 11.7 8.7e-38 129.4 8.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DUF1399 PF07173.7 KNE01109.1 - 1.5e-10 41.4 0.1 2.8e-10 40.6 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1399) RNase_T PF00929.19 KNE01112.1 - 1.4e-31 109.9 0.0 1.9e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Exonuclease Pkinase PF00069.20 KNE01113.1 - 1.6e-59 201.2 0.1 8.8e-39 133.2 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNE01113.1 - 2.3e-27 95.6 0.1 3.1e-21 75.6 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 KNE01113.1 - 2.3e-09 37.2 0.1 4.5e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 KNE01113.1 - 0.00025 20.1 0.0 0.0011 17.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KNE01113.1 - 0.0016 18.2 0.1 0.017 14.8 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KNE01113.1 - 0.022 13.5 0.0 0.049 12.4 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 KNE01113.1 - 0.039 13.0 0.7 0.18 10.8 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family bZIP_2 PF07716.10 KNE01114.1 - 2e-10 40.3 12.9 2e-10 40.3 8.9 2.9 3 0 0 3 3 3 1 Basic region leucine zipper TBPIP PF07106.8 KNE01114.1 - 0.033 13.7 12.0 0.056 12.9 8.3 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) bZIP_1 PF00170.16 KNE01114.1 - 2 8.4 28.3 0.38 10.7 14.7 2.9 2 1 0 2 2 2 0 bZIP transcription factor DUF4094 PF13334.1 KNE01114.1 - 3.9 7.9 8.6 0.89 9.9 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) PSP1 PF04468.7 KNE01115.1 - 2.3e-31 107.6 0.8 4.1e-31 106.8 0.6 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Imm8 PF15560.1 KNE01115.1 - 0.00036 20.2 0.1 0.00065 19.3 0.1 1.3 1 0 0 1 1 1 1 Immunity protein 8 SRF-TF PF00319.13 KNE01120.1 - 1.7e-23 81.5 0.2 2.4e-23 81.0 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Cadherin_C PF01049.12 KNE01120.1 - 0.71 9.8 6.9 0.14 12.1 2.4 1.6 2 0 0 2 2 2 0 Cadherin cytoplasmic region Synaphin PF05835.7 KNE01120.1 - 1.8 8.6 7.4 0.46 10.6 0.5 2.2 2 0 0 2 2 2 0 Synaphin protein PWWP PF00855.12 KNE01121.1 - 4.2e-17 62.1 0.1 1.5e-16 60.3 0.0 2.0 1 0 0 1 1 1 1 PWWP domain WD40 PF00400.27 KNE01122.1 - 0.026 14.3 5.5 2.7 8.0 0.0 4.2 4 1 0 4 4 4 0 WD domain, G-beta repeat IKI3 PF04762.7 KNE01122.1 - 0.058 11.2 0.1 0.074 10.8 0.0 1.1 1 0 0 1 1 1 0 IKI3 family PQQ_3 PF13570.1 KNE01122.1 - 2.4 8.5 7.5 11 6.4 0.2 3.5 4 0 0 4 4 4 0 PQQ-like domain Phosphorylase PF00343.15 KNE01124.1 - 0 1029.7 0.1 0 1029.4 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase Peptidase_S10 PF00450.17 KNE01126.1 - 2.9e-100 336.3 0.1 3.9e-100 335.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Ribosomal_L4 PF00573.17 KNE01127.1 - 3.5e-43 147.2 0.0 4e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Herpes_UL14 PF03580.9 KNE01127.1 - 0.017 14.9 0.2 0.026 14.3 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL14-like protein Ribosomal_S13 PF00416.17 KNE01128.1 - 1.1e-40 138.3 1.8 1.3e-40 138.1 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 KNE01128.1 - 0.0019 16.8 0.0 0.0019 16.8 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF3196 PF11428.3 KNE01128.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3196) NAD_binding_4 PF07993.7 KNE01130.1 - 1.9e-69 233.3 0.0 2.8e-69 232.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KNE01130.1 - 7.3e-69 232.1 0.0 1.1e-68 231.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 KNE01130.1 - 7.2e-12 45.3 0.0 1.7e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 KNE01130.1 - 1.4e-11 44.2 0.0 2.6e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 KNE01130.1 - 3.9e-08 34.1 0.1 1.3e-07 32.4 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 KNE01130.1 - 0.015 14.0 0.0 0.06 12.0 0.0 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KNE01130.1 - 0.023 13.6 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GP41 PF00517.12 KNE01131.1 - 0.11 12.0 0.4 0.77 9.2 0.1 2.3 1 1 1 2 2 2 0 Retroviral envelope protein CENP-F_leu_zip PF10473.4 KNE01131.1 - 0.17 11.7 9.1 0.3 10.9 6.3 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 T2SF PF00482.18 KNE01131.1 - 0.54 10.1 2.6 13 5.7 1.8 2.5 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F Fungal_trans PF04082.13 KNE01132.1 - 5.3e-29 100.8 0.0 8.8e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNE01132.1 - 4.2e-06 26.5 11.6 7.9e-06 25.6 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 KNE01132.1 - 0.00032 20.5 1.4 0.00065 19.5 0.4 2.0 2 0 0 2 2 2 1 Gal4-like dimerisation domain adh_short PF00106.20 KNE01134.1 - 1.3e-28 100.0 0.5 1.8e-28 99.5 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNE01134.1 - 3.9e-24 85.7 0.1 4.6e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KNE01134.1 - 1.2e-13 51.0 0.2 2.1e-13 50.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KNE01134.1 - 0.012 15.0 1.0 0.048 13.0 0.7 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_N PF08240.7 KNE01136.1 - 7.6e-30 102.8 1.1 1.6e-29 101.8 0.8 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KNE01136.1 - 6.3e-22 77.5 0.0 1.2e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KNE01136.1 - 4.5e-05 24.3 0.0 0.00014 22.7 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KNE01136.1 - 0.0012 19.4 0.0 0.0024 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh_C PF02826.14 KNE01136.1 - 0.018 14.1 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 KNE01136.1 - 0.018 15.4 0.0 0.04 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 KNE01136.1 - 0.043 13.2 0.3 0.084 12.2 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_31 PF13847.1 KNE01136.1 - 0.063 12.8 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 KNE01137.1 - 6.9e-30 104.1 0.5 8.5e-30 103.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNE01137.1 - 1.7e-22 80.4 0.0 2.2e-22 80.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KNE01137.1 - 1.9e-14 53.7 0.1 2.8e-14 53.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KNE01137.1 - 0.0008 18.9 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KNE01137.1 - 0.0008 18.1 0.0 0.0011 17.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 KNE01137.1 - 0.0096 15.8 0.1 0.022 14.6 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 KNE01137.1 - 0.013 14.4 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KNE01137.1 - 0.034 13.0 0.2 1.7 7.4 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain PDEase_I PF00233.14 KNE01139.1 - 9.2e-40 136.8 2.7 3e-35 122.0 0.0 3.0 3 1 0 3 3 3 2 3'5'-cyclic nucleotide phosphodiesterase Ski_Sno PF02437.12 KNE01139.1 - 0.093 12.3 0.0 0.88 9.1 0.0 2.2 2 0 0 2 2 2 0 SKI/SNO/DAC family SAM_2 PF07647.12 KNE01140.1 - 8.5e-08 31.9 0.1 1.8e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KNE01140.1 - 3.7e-06 27.0 0.1 8.1e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Synaptobrevin PF00957.16 KNE01141.1 - 1.8e-15 56.2 0.7 3.2e-15 55.5 0.5 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KNE01141.1 - 4.4e-15 55.0 0.0 7.9e-15 54.1 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Tbf5 PF06331.7 KNE01141.1 - 0.079 12.7 0.5 0.14 11.9 0.3 1.4 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 ParB PF08775.5 KNE01141.1 - 0.4 10.9 3.2 11 6.3 0.0 2.6 2 1 1 3 3 3 0 ParB family Ras PF00071.17 KNE01142.1 - 3.1e-37 127.4 0.0 5.6e-37 126.6 0.0 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KNE01142.1 - 9.1e-15 55.2 0.0 1.5e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNE01142.1 - 1.8e-08 33.8 0.2 7.5e-08 31.8 0.2 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KNE01142.1 - 7.8e-06 25.4 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KNE01142.1 - 0.00047 19.3 0.0 0.0015 17.6 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KNE01142.1 - 0.0013 18.6 0.0 0.0026 17.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KNE01142.1 - 0.029 14.4 0.0 0.078 13.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KNE01142.1 - 0.047 13.2 0.0 0.093 12.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KNE01142.1 - 0.06 13.3 0.0 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 KNE01142.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CHCH PF06747.8 KNE01144.1 - 7.4e-09 35.3 2.9 1.3e-08 34.4 2.0 1.5 1 0 0 1 1 1 1 CHCH domain YtxH PF12732.2 KNE01144.1 - 0.0087 16.3 0.1 0.028 14.7 0.1 1.8 2 0 0 2 2 2 1 YtxH-like protein PT PF04886.7 KNE01144.1 - 0.019 14.2 4.8 0.27 10.5 0.1 2.5 2 0 0 2 2 2 0 PT repeat GCK PF07802.6 KNE01144.1 - 3.2 7.9 7.5 0.41 10.8 2.2 1.8 2 0 0 2 2 2 0 GCK domain eIF-3c_N PF05470.7 KNE01144.1 - 6.5 4.7 7.3 0.65 8.0 0.1 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Fer4_20 PF14691.1 KNE01145.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.3 1 1 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster G-patch PF01585.18 KNE01146.1 - 2e-12 46.6 5.6 3.4e-12 45.9 3.8 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KNE01146.1 - 3.6e-07 29.9 0.4 6.8e-07 29.0 0.3 1.4 1 0 0 1 1 1 1 DExH-box splicing factor binding site Reo_sigmaC PF04582.7 KNE01146.1 - 0.16 11.1 1.2 0.25 10.4 0.8 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein APG17 PF04108.7 KNE01147.1 - 1.7e-70 237.9 14.0 2e-70 237.6 9.7 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF1835 PF08874.5 KNE01147.1 - 0.0012 18.7 0.2 0.0097 15.8 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1835) MbeD_MobD PF04899.7 KNE01147.1 - 4.6 7.2 10.0 9.8 6.1 0.1 3.5 3 1 1 4 4 4 0 MbeD/MobD like FUSC PF04632.7 KNE01147.1 - 8.3 4.7 8.7 3.2 6.0 0.2 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family CDC73 PF05179.9 KNE01148.1 - 2.9e-55 187.5 1.6 4.9e-55 186.7 1.1 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Ribosomal_L7Ae PF01248.21 KNE01148.1 - 0.13 11.8 0.0 0.35 10.4 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family tRNA-synt_2b PF00587.20 KNE01149.1 - 5.9e-48 162.7 0.1 8.4e-48 162.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KNE01149.1 - 5.3e-18 64.7 0.3 9.6e-18 63.9 0.2 1.4 1 0 0 1 1 1 1 Anticodon binding domain INO80_Ies4 PF08193.6 KNE01150.1 - 5e-14 52.7 10.1 1.4e-12 48.0 5.1 2.2 1 1 1 2 2 2 2 INO80 complex subunit Ies4 DUF202 PF02656.10 KNE01151.1 - 0.0021 18.2 0.1 0.0021 18.2 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) COX4_pro_2 PF07835.7 KNE01151.1 - 0.1 12.5 0.6 0.49 10.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV MDM31_MDM32 PF08118.6 KNE01152.1 - 2.6e-256 850.9 8.0 2.9e-256 850.7 5.6 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Aminotran_5 PF00266.14 KNE01153.1 - 6.5e-20 71.2 0.0 8.6e-20 70.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KNE01153.1 - 0.00014 20.9 0.0 0.0002 20.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KNE01153.1 - 0.032 13.2 0.2 0.077 12.0 0.1 1.6 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 KNE01153.1 - 0.037 12.3 0.0 0.053 11.7 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Cellulase PF00150.13 KNE01154.1 - 2.7e-10 39.9 11.6 1.1e-09 37.9 8.0 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ribosomal_60s PF00428.14 KNE01158.1 - 1.4e-23 83.0 15.2 1.7e-23 82.8 10.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Shadoo PF14999.1 KNE01158.1 - 0.5 10.2 7.2 0.81 9.5 5.0 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Ribosomal_L13e PF01294.13 KNE01159.1 - 5.8e-61 205.0 10.1 5.8e-61 205.0 7.0 1.8 1 1 1 2 2 2 1 Ribosomal protein L13e 4HBT_3 PF13622.1 KNE01159.1 - 0.15 11.7 1.6 0.34 10.6 0.6 2.0 1 1 1 2 2 2 0 Thioesterase-like superfamily RIC1 PF07064.8 KNE01160.1 - 9.9e-17 61.2 3.3 2.2e-16 60.0 2.3 1.6 1 0 0 1 1 1 1 RIC1 Apc4_WD40 PF12894.2 KNE01160.1 - 0.086 12.3 0.2 7.9 6.0 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Complex1_LYR PF05347.10 KNE01161.1 - 6.2e-10 38.7 0.5 1.1e-09 37.8 0.3 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KNE01161.1 - 9.6e-08 32.1 0.3 2.2e-07 30.9 0.2 1.6 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KNE01161.1 - 0.00077 19.9 1.3 0.001 19.4 0.9 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Tubulin_C PF03953.12 KNE01162.1 - 4.9e-48 162.3 0.0 8.4e-48 161.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 KNE01162.1 - 2.9e-35 122.0 0.0 6.5e-35 120.9 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.1 KNE01162.1 - 0.0012 18.3 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Syntaxin PF00804.20 KNE01163.1 - 3.3e-19 68.9 3.8 3.3e-19 68.9 2.6 3.2 2 1 1 3 3 3 1 Syntaxin SNARE PF05739.14 KNE01163.1 - 2.8e-16 58.9 2.8 2.8e-16 58.9 1.9 2.7 2 1 0 2 2 2 1 SNARE domain Sed5p PF11416.3 KNE01163.1 - 9.1e-15 53.7 1.4 2.2e-14 52.5 1.0 1.7 1 0 0 1 1 1 1 Integral membrane protein Sed5p FlaC_arch PF05377.6 KNE01163.1 - 0.00013 21.8 0.2 0.00013 21.8 0.1 3.1 2 2 0 2 2 2 1 Flagella accessory protein C (FlaC) MCPsignal PF00015.16 KNE01163.1 - 0.00084 18.9 4.3 0.0016 18.0 0.3 2.3 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF16 PF01519.11 KNE01163.1 - 0.021 15.0 9.3 0.038 14.1 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 Flagellin_C PF00700.16 KNE01163.1 - 0.17 12.0 5.5 1.1 9.5 0.2 2.7 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region DUF745 PF05335.8 KNE01163.1 - 0.2 11.1 8.5 1.5 8.2 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) zf-C4H2 PF10146.4 KNE01163.1 - 0.5 10.3 5.2 0.63 10.0 0.4 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein Osmo_CC PF08946.5 KNE01163.1 - 0.96 9.5 6.8 2.7 8.1 0.4 3.5 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Laminin_II PF06009.7 KNE01163.1 - 4.9 6.9 9.3 2.1 8.0 0.4 2.9 2 1 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.7 KNE01163.1 - 5 6.9 7.1 3.9 7.2 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 KNE01163.1 - 5.4 6.9 7.7 5.4 6.9 0.7 2.9 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Snf7 PF03357.16 KNE01164.1 - 2e-42 144.4 21.1 2e-42 144.4 14.7 1.9 1 1 1 2 2 2 1 Snf7 YppG PF14179.1 KNE01164.1 - 0.45 11.1 5.4 1.8 9.1 0.1 2.7 2 1 1 3 3 3 0 YppG-like protein DUF3573 PF12097.3 KNE01164.1 - 1.1 7.7 8.0 1.1 7.7 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) FlaC_arch PF05377.6 KNE01164.1 - 3.8 7.4 9.5 15 5.5 0.8 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 KNE01164.1 - 4 6.9 20.2 1 8.8 1.1 4.1 2 1 0 4 4 4 0 Septum formation initiator Enkurin PF13864.1 KNE01164.1 - 8.5 6.6 19.5 3.5 7.8 0.9 3.7 2 2 1 3 3 3 0 Calmodulin-binding Snapin_Pallidin PF14712.1 KNE01164.1 - 9.8 6.5 17.3 0.25 11.7 5.0 2.9 2 1 0 3 3 3 0 Snapin/Pallidin RNA_pol PF00940.14 KNE01165.1 - 8.3e-163 541.5 0.0 1.7e-162 540.5 0.0 1.6 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 KNE01165.1 - 2.1e-82 276.9 0.2 4.5e-82 275.8 0.2 1.6 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal ThuA PF06283.6 KNE01165.1 - 0.086 12.5 0.1 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 Trehalose utilisation Mob1_phocein PF03637.12 KNE01166.1 - 2.6e-70 235.6 0.9 3e-70 235.4 0.6 1.0 1 0 0 1 1 1 1 Mob1/phocein family DUF682 PF05081.7 KNE01166.1 - 0.071 12.6 0.0 0.19 11.3 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF682) PS_Dcarbxylase PF02666.10 KNE01168.1 - 4e-77 258.0 0.0 4.3e-76 254.7 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Big_5 PF13205.1 KNE01168.1 - 0.0025 18.3 0.3 0.005 17.4 0.2 1.4 1 0 0 1 1 1 1 Bacterial Ig-like domain Apc1 PF12859.2 KNE01170.1 - 2.1e-18 66.4 0.0 6.4e-18 64.9 0.0 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 KNE01170.1 - 0.00077 19.5 5.5 0.15 12.3 0.0 5.1 5 0 0 5 5 5 1 Proteasome/cyclosome repeat GTP_EFTU PF00009.22 KNE01171.1 - 1.3e-60 204.0 0.1 1.7e-60 203.6 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KNE01171.1 - 1.3e-24 86.1 0.0 4.3e-24 84.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KNE01171.1 - 8.4e-20 70.6 3.5 8.6e-20 70.6 1.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KNE01171.1 - 1.3e-06 27.9 0.7 3e-06 26.7 0.2 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 KNE01171.1 - 3.2e-05 23.8 0.0 5.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KNE01171.1 - 0.0029 18.0 0.0 0.0051 17.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein cobW PF02492.14 KNE01171.1 - 0.15 11.4 1.3 0.2 11.0 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KNE01171.1 - 0.16 11.4 1.1 9.7 5.6 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CbiA PF01656.18 KNE01171.1 - 0.17 11.2 1.7 6.2 6.1 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Bul1_N PF04425.7 KNE01172.1 - 5.3e-92 308.6 0.4 3.7e-81 272.9 0.0 2.2 1 1 1 2 2 2 2 Bul1 N terminus Bul1_C PF04426.7 KNE01172.1 - 1.5e-17 63.7 0.4 1.3e-08 34.3 0.0 2.7 1 1 1 2 2 2 2 Bul1 C terminus INCENP_ARK-bind PF03941.10 KNE01174.1 - 9.1e-13 47.8 0.3 2.4e-12 46.4 0.2 1.8 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region TPR_11 PF13414.1 KNE01175.1 - 2.4e-15 55.9 7.9 6.9e-14 51.2 1.1 2.6 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 KNE01175.1 - 1.4e-12 46.5 14.8 1.3e-05 24.6 1.2 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KNE01175.1 - 6.3e-12 44.4 6.7 0.0034 17.1 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 KNE01175.1 - 3.7e-06 26.9 5.5 5.3e-06 26.4 3.2 1.7 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KNE01175.1 - 2.6e-05 23.6 0.5 0.039 13.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KNE01175.1 - 9.7e-05 22.6 0.4 0.0085 16.4 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KNE01175.1 - 0.0017 18.1 3.5 2.6 7.9 0.0 3.5 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat Pox_T4_N PF04491.7 KNE01175.1 - 0.0029 17.4 0.2 0.046 13.5 0.0 2.5 2 0 0 2 2 2 1 Poxvirus T4 protein, N terminus TPR_12 PF13424.1 KNE01175.1 - 0.0033 17.3 8.2 0.17 11.8 0.0 2.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KNE01175.1 - 0.0038 17.3 1.1 0.1 12.8 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KNE01175.1 - 0.013 16.2 0.4 0.36 11.5 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KNE01175.1 - 0.042 13.6 6.9 1.3 8.9 0.3 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF3808 PF10300.4 KNE01175.1 - 0.046 12.3 2.5 0.067 11.7 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) TPR_14 PF13428.1 KNE01175.1 - 0.11 13.1 0.1 1 10.2 0.0 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat MIT PF04212.13 KNE01175.1 - 0.41 10.5 7.5 5.4 6.9 0.0 3.3 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain Bul1_N PF04425.7 KNE01176.1 - 1.1e-95 320.7 0.0 1.8e-95 320.0 0.0 1.2 1 0 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.7 KNE01176.1 - 5.5e-24 84.7 2.7 3e-22 79.0 1.9 2.5 1 1 0 1 1 1 1 Bul1 C terminus G_glu_transpept PF01019.16 KNE01177.1 - 3.3e-131 438.2 0.0 4e-131 437.9 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Carn_acyltransf PF00755.15 KNE01178.1 - 8.7e-167 555.7 0.0 3.7e-151 504.1 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase DUF1708 PF08101.6 KNE01179.1 - 1.4e-132 442.5 1.0 4.2e-132 440.9 0.7 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) bZIP_1 PF00170.16 KNE01180.1 - 1.9e-07 30.9 7.2 1.9e-07 30.9 5.0 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KNE01180.1 - 2.4e-05 24.0 8.9 2.4e-05 24.0 6.1 2.4 1 1 1 2 2 2 1 Basic region leucine zipper Spore_coat_CotO PF14153.1 KNE01180.1 - 0.014 14.8 7.6 0.023 14.1 5.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF3584 PF12128.3 KNE01180.1 - 0.029 11.7 6.0 0.037 11.3 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fmp27 PF10344.4 KNE01180.1 - 0.55 7.8 5.4 0.75 7.3 3.7 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Phlebovirus_NSM PF07246.6 KNE01180.1 - 1.2 8.2 6.3 1.7 7.7 4.4 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M RR_TM4-6 PF06459.7 KNE01180.1 - 4.4 7.1 12.7 6.9 6.4 8.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PAT1 PF09770.4 KNE01180.1 - 9.4 4.3 36.8 0.13 10.4 12.6 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 PHO4 PF01384.15 KNE01181.1 - 0.08 11.5 0.0 0.08 11.5 0.0 1.1 1 0 0 1 1 1 0 Phosphate transporter family Glyco_hydro_47 PF01532.15 KNE01182.1 - 3.7e-164 546.6 0.2 4.3e-164 546.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Zn_clus PF00172.13 KNE01184.1 - 0.00046 20.0 8.2 0.0008 19.2 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF904 PF06005.7 KNE01184.1 - 0.0014 18.9 0.8 0.0031 17.7 0.2 1.9 2 0 0 2 2 1 1 Protein of unknown function (DUF904) T4SS PF07996.6 KNE01184.1 - 0.0014 18.5 1.1 0.0025 17.7 0.7 1.3 1 0 0 1 1 1 1 Type IV secretion system proteins SlyX PF04102.7 KNE01184.1 - 0.0036 17.6 8.9 0.012 15.9 6.2 1.9 1 0 0 1 1 1 1 SlyX ATG16 PF08614.6 KNE01184.1 - 0.0062 16.3 0.7 0.013 15.3 0.5 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) FlxA PF14282.1 KNE01184.1 - 0.007 16.2 10.2 0.016 15.1 7.1 1.5 1 0 0 1 1 1 1 FlxA-like protein TSC22 PF01166.13 KNE01184.1 - 0.0081 16.1 0.9 0.04 13.8 0.2 2.4 2 0 0 2 2 2 1 TSC-22/dip/bun family Med9 PF07544.8 KNE01184.1 - 0.023 14.4 6.1 0.056 13.1 4.2 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF4140 PF13600.1 KNE01184.1 - 0.029 14.7 2.9 0.073 13.5 2.0 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF2730 PF10805.3 KNE01184.1 - 0.034 13.8 0.6 0.081 12.6 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF4349 PF14257.1 KNE01184.1 - 0.036 13.3 1.5 0.06 12.5 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) IncA PF04156.9 KNE01184.1 - 0.038 13.5 3.7 0.086 12.4 2.5 1.5 1 0 0 1 1 1 0 IncA protein Cep57_MT_bd PF06657.8 KNE01184.1 - 0.04 13.8 2.2 0.11 12.4 1.5 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF4407 PF14362.1 KNE01184.1 - 0.04 12.8 0.7 0.061 12.2 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin PF00804.20 KNE01184.1 - 0.044 13.9 2.1 0.11 12.6 1.5 1.6 1 0 0 1 1 1 0 Syntaxin Spc24 PF08286.6 KNE01184.1 - 0.053 13.2 0.9 0.15 11.7 0.1 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TBPIP PF07106.8 KNE01184.1 - 0.065 12.7 1.3 0.13 11.8 0.9 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) YPEB PF14620.1 KNE01184.1 - 0.084 11.8 0.4 0.13 11.2 0.3 1.2 1 0 0 1 1 1 0 YpeB sporulation HR1 PF02185.11 KNE01184.1 - 0.089 12.5 7.1 0.22 11.2 4.9 1.7 1 0 0 1 1 1 0 Hr1 repeat DUF3373 PF11853.3 KNE01184.1 - 0.12 10.9 0.2 0.17 10.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Prefoldin PF02996.12 KNE01184.1 - 0.12 12.0 5.9 0.28 10.8 4.1 1.6 1 0 0 1 1 1 0 Prefoldin subunit Ribosomal_L29 PF00831.18 KNE01184.1 - 0.13 12.0 4.7 0.29 10.8 3.3 1.6 1 0 0 1 1 1 0 Ribosomal L29 protein DUF3573 PF12097.3 KNE01184.1 - 0.18 10.3 0.1 0.34 9.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) EAP30 PF04157.11 KNE01184.1 - 0.28 10.3 3.2 4.6 6.3 1.9 2.2 2 0 0 2 2 2 0 EAP30/Vps36 family IFP_35_N PF07334.8 KNE01184.1 - 0.37 10.7 6.6 0.38 10.7 2.8 2.3 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF342 PF03961.8 KNE01184.1 - 0.41 9.0 0.8 0.65 8.3 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) GrpE PF01025.14 KNE01184.1 - 0.69 9.4 5.3 1.4 8.4 3.7 1.4 1 0 0 1 1 1 0 GrpE Occludin_ELL PF07303.8 KNE01184.1 - 0.87 10.3 4.9 2.1 9.1 0.6 3.0 3 0 0 3 3 3 0 Occludin homology domain DUF3847 PF12958.2 KNE01184.1 - 2.6 7.8 7.6 6.8 6.5 5.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) DUF2802 PF10975.3 KNE01184.1 - 3.1 7.6 9.0 6.3 6.6 6.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) DivIC PF04977.10 KNE01184.1 - 7.9 6.0 8.5 22 4.6 5.9 1.7 1 0 0 1 1 1 0 Septum formation initiator Cyt-b5 PF00173.23 KNE01185.1 - 1.3e-09 37.7 0.0 1.8e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cys_Met_Meta_PP PF01053.15 KNE01186.1 - 3.9e-37 127.4 0.0 5.3e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KNE01186.1 - 5.7e-06 25.5 0.0 1.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II HMG-CoA_red PF00368.13 KNE01187.1 - 7.6e-159 528.3 0.6 1.1e-158 527.8 0.5 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 KNE01187.1 - 9e-24 83.9 0.9 1.7e-22 79.7 0.1 2.7 2 0 0 2 2 2 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 KNE01187.1 - 1.7e-11 43.7 9.1 1.7e-11 43.7 6.3 1.9 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation DUF4282 PF14110.1 KNE01187.1 - 2.2 8.5 9.0 0.21 11.7 1.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4282) Imm13 PF15564.1 KNE01189.1 - 0.011 15.4 0.2 3.1 7.5 0.0 2.7 2 1 1 3 3 3 0 Immunity protein 13 Rep_fac_C PF08542.6 KNE01189.1 - 0.016 15.1 0.1 25 4.9 0.0 3.4 3 1 0 3 3 3 0 Replication factor C C-terminal domain NPV_P10 PF05531.7 KNE01189.1 - 0.15 12.3 3.7 2.2 8.5 0.2 3.1 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Tubulin PF00091.20 KNE01191.1 - 2.3e-56 191.0 0.2 4.8e-56 189.9 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KNE01191.1 - 4.7e-16 58.9 0.0 8.4e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Aminotran_1_2 PF00155.16 KNE01192.1 - 3.3e-23 82.2 0.0 4e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.15 KNE01192.1 - 0.2 10.1 0.0 0.3 9.5 0.0 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain BAR_2 PF10455.4 KNE01193.1 - 8.5e-63 211.9 7.9 1.3e-62 211.3 5.4 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 KNE01193.1 - 1.7e-13 50.6 6.2 5.7e-13 48.9 4.3 1.8 1 1 0 1 1 1 1 BAR domain Arfaptin PF06456.8 KNE01193.1 - 0.026 13.8 2.8 0.19 11.0 0.0 2.8 2 1 0 2 2 2 0 Arfaptin-like domain DUF2458 PF10454.4 KNE01193.1 - 0.065 13.1 5.6 4 7.3 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2458) Transcrip_act PF04949.8 KNE01193.1 - 0.099 12.2 2.1 0.2 11.2 0.3 2.2 2 0 0 2 2 2 0 Transcriptional activator IFT46_B_C PF12317.3 KNE01193.1 - 0.3 10.4 4.8 0.44 9.8 0.3 2.5 2 1 1 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal DUF2215 PF10225.4 KNE01193.1 - 0.71 9.2 2.5 0.31 10.4 0.1 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) IL6 PF00489.12 KNE01193.1 - 1.1 8.8 5.1 0.54 9.8 0.4 2.5 2 2 1 3 3 3 0 Interleukin-6/G-CSF/MGF family Spectrin PF00435.16 KNE01193.1 - 1.1 9.5 6.0 21 5.4 0.2 3.1 3 1 0 3 3 3 0 Spectrin repeat DUF148 PF02520.12 KNE01193.1 - 1.2 8.9 7.0 0.4 10.4 0.7 3.2 2 2 1 3 3 3 0 Domain of unknown function DUF148 Fib_alpha PF08702.5 KNE01193.1 - 3.8 7.6 9.7 0.63 10.1 0.8 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family AA_kinase PF00696.23 KNE01194.1 - 3.4e-39 134.8 0.1 5.8e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 KNE01194.1 - 6.4e-12 44.6 1.2 5.5e-06 25.7 0.3 2.9 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 KNE01194.1 - 1.4e-06 27.7 2.2 7.3e-05 22.2 0.4 2.5 2 0 0 2 2 2 2 ACT domain DUF763 PF05559.6 KNE01194.1 - 0.22 10.4 2.8 0.37 9.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF763) Ofd1_CTDD PF10637.4 KNE01196.1 - 3.4e-96 321.4 0.1 2.4e-92 308.8 0.0 2.5 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 KNE01196.1 - 8e-13 48.7 0.1 1.9e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KNE01196.1 - 2.3e-06 27.8 0.1 4.4e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NAD_binding_1 PF00175.16 KNE01197.1 - 1.8e-30 105.7 0.0 3e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KNE01197.1 - 3.6e-28 97.6 0.0 5.7e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KNE01197.1 - 8.3e-07 29.0 0.0 0.00018 21.4 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Cation_efflux PF01545.16 KNE01197.1 - 0.083 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Cation efflux family DUF2080 PF09853.4 KNE01198.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative transposon-encoded protein (DUF2080) DUF946 PF06101.6 KNE01199.1 - 6.5e-12 44.2 4.7 9e-12 43.7 2.0 2.1 2 1 1 3 3 3 1 Plant protein of unknown function (DUF946) AA_permease PF00324.16 KNE01201.1 - 1.7e-136 455.3 43.5 1.9e-136 455.1 30.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KNE01201.1 - 5e-40 137.3 45.6 5.8e-40 137.1 31.6 1.0 1 0 0 1 1 1 1 Amino acid permease Rap_GAP PF02145.10 KNE01202.1 - 5.1e-53 179.2 2.7 9.3e-53 178.4 1.8 1.5 1 0 0 1 1 1 1 Rap/ran-GAP DUF3384 PF11864.3 KNE01202.1 - 1.1e-52 179.0 18.2 2.3e-52 178.0 12.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Tuberin PF03542.11 KNE01202.1 - 3e-16 59.4 0.6 3e-16 59.4 0.4 2.4 3 0 0 3 3 3 1 Tuberin AARP2CN PF08142.7 KNE01203.1 - 0.054 13.0 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 AARP2CN (NUC121) domain SIS PF01380.17 KNE01204.1 - 1.7e-11 43.8 0.0 3.4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.1 KNE01204.1 - 0.0015 18.2 0.0 0.018 14.7 0.0 2.3 1 1 1 2 2 2 1 SIS domain FliG_M PF14841.1 KNE01204.1 - 0.48 10.4 3.5 2.1 8.4 0.2 2.6 3 0 0 3 3 3 0 FliG middle domain PUF PF00806.14 KNE01206.1 - 4.8e-59 192.6 14.9 1.6e-08 33.5 0.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat THP2 PF09432.5 KNE01206.1 - 0.0072 16.1 0.5 0.016 15.0 0.3 1.5 1 0 0 1 1 1 1 Tho complex subunit THP2 SapB_2 PF03489.12 KNE01206.1 - 0.055 13.5 0.2 4.3 7.4 0.0 2.9 3 0 0 3 3 3 0 Saposin-like type B, region 2 BRAP2 PF07576.7 KNE01207.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 BRCA1-associated protein 2 WD40 PF00400.27 KNE01208.1 - 4.2e-08 32.7 0.3 0.0006 19.5 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat TPR_2 PF07719.12 KNE01209.1 - 2e-33 111.5 21.1 2.9e-05 23.6 0.2 10.9 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_11 PF13414.1 KNE01209.1 - 1.5e-28 98.1 27.8 3.1e-10 39.5 0.4 7.7 6 2 1 7 7 7 6 TPR repeat TPR_1 PF00515.23 KNE01209.1 - 2.5e-26 90.1 28.7 9.6e-07 28.1 0.9 10.4 11 0 0 11 11 10 5 Tetratricopeptide repeat Apc3 PF12895.2 KNE01209.1 - 3.9e-24 84.5 23.3 1.6e-18 66.5 0.0 6.8 4 2 3 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KNE01209.1 - 3.4e-22 78.5 14.1 7.2e-06 26.5 0.0 8.5 7 1 2 9 9 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 KNE01209.1 - 7.7e-21 73.8 16.2 4.6e-11 42.4 2.5 8.2 3 3 5 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 KNE01209.1 - 1.6e-19 68.1 13.9 7.9e-05 22.1 0.5 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 KNE01209.1 - 5.6e-19 66.9 13.3 0.026 15.1 0.0 10.3 7 2 5 12 12 11 5 Tetratricopeptide repeat TPR_19 PF14559.1 KNE01209.1 - 5.8e-18 64.9 12.3 0.066 13.5 0.2 8.5 5 2 4 9 9 9 7 Tetratricopeptide repeat TPR_17 PF13431.1 KNE01209.1 - 1.4e-13 49.8 8.7 0.057 13.6 0.0 8.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 KNE01209.1 - 9.3e-13 46.9 10.5 0.0055 16.4 0.0 8.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 KNE01209.1 - 1.4e-11 43.8 7.1 0.037 13.9 0.8 7.2 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_15 PF13429.1 KNE01209.1 - 1.5e-10 40.6 0.8 0.006 15.6 0.0 4.6 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 KNE01209.1 - 8.1e-09 35.3 14.2 0.47 11.0 0.2 8.2 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 KNE01209.1 - 1.8e-05 24.4 2.1 0.099 12.5 0.0 5.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.4 KNE01209.1 - 0.00015 21.6 3.2 0.16 11.9 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Coatomer_E PF04733.9 KNE01209.1 - 0.00069 18.9 1.3 0.063 12.4 0.1 3.5 4 0 0 4 4 4 1 Coatomer epsilon subunit PPR PF01535.15 KNE01209.1 - 0.036 14.0 0.9 96 3.2 0.0 5.2 6 0 0 6 6 5 0 PPR repeat MIT PF04212.13 KNE01209.1 - 0.17 11.7 4.2 3.8 7.4 0.1 3.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain WD40 PF00400.27 KNE01210.1 - 3.3e-34 115.5 1.3 5e-10 38.8 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 KNE01210.1 - 1.5e-07 29.9 0.2 0.00081 17.6 0.1 2.6 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KNE01210.1 - 7.6e-05 21.6 3.0 1.2 7.7 0.1 4.2 1 1 3 4 4 4 3 Nup133 N terminal like BBS2_Mid PF14783.1 KNE01210.1 - 9.8e-05 22.0 1.3 1.8 8.3 0.0 4.5 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region NTR PF01759.16 KNE01210.1 - 0.17 11.4 2.4 4.5 6.8 0.0 3.4 5 0 0 5 5 5 0 UNC-6/NTR/C345C module AlaDh_PNT_N PF05222.10 KNE01211.1 - 3.2e-29 101.6 0.0 4.5e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KNE01211.1 - 2.7e-19 69.3 0.0 3.9e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FGGY_N PF00370.16 KNE01213.1 - 6.7e-16 58.3 0.0 3.9e-10 39.4 0.0 3.6 2 2 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 KNE01213.1 - 4.2e-12 46.1 0.0 9.9e-11 41.6 0.0 2.7 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain SPC12 PF06645.8 KNE01214.1 - 6.2e-23 80.4 2.4 7e-23 80.2 1.7 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF2651 PF10852.3 KNE01214.1 - 0.11 12.8 4.9 0.15 12.3 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2651) DUF3040 PF11239.3 KNE01214.1 - 0.27 11.3 1.8 0.29 11.2 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF4191 PF13829.1 KNE01214.1 - 0.3 10.1 1.6 0.32 10.0 1.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) VirB3 PF05101.8 KNE01214.1 - 8.1 6.5 7.0 12 5.9 4.8 1.3 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Hap4_Hap_bind PF10297.4 KNE01216.1 - 0.0002 21.0 1.0 0.00046 19.9 0.7 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 Aldedh PF00171.17 KNE01218.1 - 1.4e-132 442.3 0.1 1.6e-132 442.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family hDGE_amylase PF14701.1 KNE01219.1 - 5.9e-163 542.6 0.0 8.4e-163 542.1 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 KNE01219.1 - 1.1e-116 389.6 0.1 2.5e-116 388.4 0.0 1.6 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 KNE01219.1 - 1.5e-76 257.0 0.0 2.5e-76 256.3 0.0 1.4 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 KNE01219.1 - 1.2e-21 76.3 0.1 2.3e-21 75.3 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 KNE01219.1 - 2.5e-07 30.4 0.1 0.00015 21.3 0.0 2.4 2 0 0 2 2 2 2 Alpha amylase, catalytic domain GST_C_2 PF13410.1 KNE01220.1 - 2.6e-09 36.8 0.0 6.6e-09 35.5 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KNE01220.1 - 7.3e-07 29.0 0.2 1.4e-06 28.1 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KNE01220.1 - 4.7e-06 26.9 0.1 6.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TIP120 PF08623.5 KNE01220.1 - 0.091 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) Sugar_tr PF00083.19 KNE01222.1 - 3e-31 108.4 37.3 4.4e-21 74.9 8.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KNE01222.1 - 3.8e-22 78.4 40.8 2.3e-11 43.0 11.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Transgly_assoc PF04226.8 KNE01222.1 - 0.27 11.3 0.1 0.27 11.3 0.1 4.1 4 1 1 5 5 5 0 Transglycosylase associated protein Tho2 PF11262.3 KNE01223.1 - 3.4e-70 236.4 5.2 3.4e-70 236.4 3.6 2.6 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 KNE01223.1 - 6.2e-28 96.4 0.2 1.9e-27 94.8 0.2 1.9 1 0 0 1 1 1 1 Transcription- and export-related complex subunit zf-C2H2 PF00096.21 KNE01224.1 - 7e-22 76.3 62.8 0.0002 21.4 1.9 8.3 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNE01224.1 - 4.8e-15 54.7 59.8 0.0072 16.5 0.6 8.3 8 0 0 8 8 8 8 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KNE01224.1 - 6e-08 32.5 65.3 0.001 19.2 0.1 9.1 7 2 2 9 9 9 5 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KNE01224.1 - 9.9e-08 31.9 35.7 0.016 15.3 1.6 7.4 7 0 0 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KNE01224.1 - 0.039 14.1 28.9 6.2 7.1 0.2 7.7 8 0 0 8 8 8 0 Zinc-finger of C2H2 type Myb_DNA-binding PF00249.26 KNE01225.1 - 1.6e-22 79.2 1.8 5.3e-10 39.2 0.0 3.1 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KNE01225.1 - 3.4e-21 75.0 3.5 6.7e-13 48.5 0.5 3.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain T2SF PF00482.18 KNE01225.1 - 0.14 12.0 0.6 0.51 10.2 0.4 2.0 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F HBS1_N PF08938.5 KNE01225.1 - 0.46 10.6 5.1 0.24 11.5 1.1 2.5 2 0 0 2 2 2 0 HBS1 N-terminus BRO1 PF03097.13 KNE01226.1 - 1.1e-82 277.8 0.3 1.1e-82 277.8 0.2 2.1 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KNE01226.1 - 2.5e-52 177.7 12.5 5.1e-52 176.6 8.7 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV IPPT PF01715.12 KNE01227.1 - 2.8e-70 236.2 0.2 4.5e-70 235.5 0.1 1.3 1 0 0 1 1 1 1 IPP transferase AAA_18 PF13238.1 KNE01227.1 - 0.049 13.9 0.6 0.049 13.9 0.4 2.3 2 1 0 2 2 2 0 AAA domain Arginase PF00491.16 KNE01227.1 - 0.12 11.6 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Arginase family DUF1752 PF08550.5 KNE01231.1 - 1.5e-10 40.4 5.1 3.2e-10 39.4 3.5 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF3661 PF12400.3 KNE01232.1 - 1.2e-39 135.3 5.8 2.2e-39 134.4 4.0 1.4 1 0 0 1 1 1 1 Vaculolar membrane protein EVC2_like PF12297.3 KNE01232.1 - 0.092 11.3 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein COX17 PF05051.8 KNE01233.1 - 1.1e-21 76.5 7.5 1.3e-21 76.3 5.2 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.8 KNE01233.1 - 0.00032 20.5 1.1 0.00055 19.7 0.8 1.5 1 1 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 KNE01233.1 - 0.0071 16.1 3.9 0.0076 16.0 0.0 2.1 1 1 1 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF1903 PF08991.5 KNE01233.1 - 0.39 10.9 5.5 0.06 13.5 1.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1903) Vps54 PF07928.7 KNE01234.1 - 3.4e-30 104.9 2.7 4.1e-30 104.6 0.2 2.4 2 0 0 2 2 2 1 Vps54-like protein DIOX_N PF14226.1 KNE01235.1 - 2.3e-26 92.6 0.0 7.2e-26 91.0 0.0 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KNE01235.1 - 3.5e-15 56.1 0.0 7.9e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Speriolin_N PF15058.1 KNE01236.1 - 0.066 13.1 0.2 0.066 13.1 0.1 1.7 2 0 0 2 2 2 0 Speriolin N terminus Mito_carr PF00153.22 KNE01237.1 - 1e-47 159.7 3.8 2.9e-16 58.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HATPase_c_3 PF13589.1 KNE01238.1 - 8.2e-15 54.6 0.0 1.8e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 KNE01238.1 - 4.6e-14 52.2 0.0 1.1e-13 51.0 0.0 1.6 1 1 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 KNE01238.1 - 2.3e-10 40.1 0.0 5.9e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NPCC PF08058.6 KNE01239.1 - 1.8e-26 92.7 1.0 6.7e-26 90.8 0.1 2.0 2 0 0 2 2 2 1 Nuclear pore complex component 4HBT_3 PF13622.1 KNE01240.1 - 7e-38 130.8 0.0 8.6e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KNE01240.1 - 4.5e-10 39.2 2.8 3e-05 23.6 0.1 3.6 3 1 0 3 3 3 3 Acyl-CoA thioesterase 4HBT_3 PF13622.1 KNE01241.1 - 8.2e-24 84.7 0.0 1.2e-23 84.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KNE01241.1 - 3.9e-08 32.9 0.3 2.8e-06 26.9 0.1 2.8 2 1 0 2 2 2 1 Acyl-CoA thioesterase 4HBT_3 PF13622.1 KNE01243.1 - 3.2e-30 105.7 0.0 4e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KNE01243.1 - 3.8e-12 45.9 0.6 2.3e-06 27.2 0.1 2.5 2 0 0 2 2 2 2 Acyl-CoA thioesterase Sec1 PF00995.18 KNE01244.1 - 7.8e-38 130.4 6.7 1.3e-37 129.6 4.6 1.4 1 0 0 1 1 1 1 Sec1 family COX7C PF02935.11 KNE01247.1 - 3.4e-14 52.3 4.2 3.5e-14 52.3 2.9 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc VHS PF00790.14 KNE01249.1 - 0.026 14.1 0.5 0.12 11.9 0.0 2.2 2 0 0 2 2 2 0 VHS domain DUF2853 PF11015.3 KNE01249.1 - 0.044 14.2 0.1 0.11 12.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2853) Iso_dh PF00180.15 KNE01251.1 - 2.3e-72 243.8 0.0 2.7e-72 243.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PcfK PF14058.1 KNE01252.1 - 0.43 10.7 7.4 0.47 10.5 5.1 1.0 1 0 0 1 1 1 0 PcfK-like protein COG6 PF06419.6 KNE01259.1 - 3.4e-132 441.6 24.4 5.3e-132 441.0 16.9 1.2 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Fmp27_WPPW PF10359.4 KNE01259.1 - 0.008 14.6 4.1 0.071 11.5 2.8 2.1 1 1 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain YaeQ PF07152.7 KNE01259.1 - 0.051 12.8 0.7 0.24 10.6 0.0 2.3 2 1 0 2 2 2 0 YaeQ protein Diphthamide_syn PF01866.12 KNE01261.1 - 2.5e-115 384.9 0.0 3e-115 384.7 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein SHQ1 PF04925.10 KNE01262.1 - 1.3e-75 253.0 1.6 1.9e-75 252.4 1.1 1.1 1 0 0 1 1 1 1 SHQ1 protein DUF2722 PF10846.3 KNE01263.1 - 4.3e-80 269.7 25.3 1.9e-79 267.6 17.5 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2722) ADH_N PF08240.7 KNE01264.1 - 0.18 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain LMBR1 PF04791.11 KNE01265.1 - 2.5e-21 75.8 21.5 3.4e-21 75.3 14.9 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein ABC_tran PF00005.22 KNE01266.1 - 4e-44 150.2 5.0 3.4e-21 75.9 0.0 3.2 4 0 0 4 4 2 2 ABC transporter ABC_tran_2 PF12848.2 KNE01266.1 - 2e-20 72.3 4.1 2e-20 72.3 2.8 3.8 4 0 0 4 4 4 1 ABC transporter AAA_21 PF13304.1 KNE01266.1 - 1.6e-16 61.1 20.0 6e-08 32.9 0.1 5.7 4 2 0 5 5 5 3 AAA domain SMC_N PF02463.14 KNE01266.1 - 1.7e-08 33.9 1.4 0.0013 18.0 0.0 3.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KNE01266.1 - 2.5e-08 34.7 3.2 0.0009 20.0 0.0 3.9 4 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 KNE01266.1 - 8.1e-06 25.2 0.5 0.081 12.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KNE01266.1 - 9.4e-06 24.9 0.0 0.044 12.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 KNE01266.1 - 1.3e-05 25.6 0.0 0.12 12.9 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_28 PF13521.1 KNE01266.1 - 1.5e-05 25.0 3.1 0.063 13.2 0.4 3.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KNE01266.1 - 2.4e-05 24.4 0.7 0.48 10.5 0.2 3.5 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.1 KNE01266.1 - 4.5e-05 23.5 1.0 0.011 15.7 0.2 3.0 2 1 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 KNE01266.1 - 5.3e-05 22.9 0.5 0.27 10.9 0.0 3.0 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KNE01266.1 - 0.00013 21.8 0.2 0.49 10.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA PF00004.24 KNE01266.1 - 0.00023 21.3 1.2 0.59 10.3 0.1 4.1 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KNE01266.1 - 0.00025 21.4 26.9 0.15 12.3 0.0 5.1 5 0 0 5 5 5 2 AAA domain AAA_18 PF13238.1 KNE01266.1 - 0.00069 19.9 8.2 0.16 12.2 0.0 3.6 4 1 0 4 4 2 2 AAA domain MMR_HSR1 PF01926.18 KNE01266.1 - 0.0009 19.1 1.2 0.084 12.8 0.0 3.4 3 1 0 3 3 3 1 50S ribosome-binding GTPase NACHT PF05729.7 KNE01266.1 - 0.0017 18.0 1.6 0.55 9.8 0.0 2.8 3 0 0 3 3 2 1 NACHT domain PduV-EutP PF10662.4 KNE01266.1 - 0.002 17.6 0.2 1 8.8 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation T2SE PF00437.15 KNE01266.1 - 0.0025 16.7 0.0 0.059 12.2 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein ATP-synt_ab PF00006.20 KNE01266.1 - 0.0026 17.2 0.0 0.028 13.9 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 KNE01266.1 - 0.0031 16.9 0.0 1.8 7.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KNE01266.1 - 0.0042 17.2 0.0 5.4 7.2 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 KNE01266.1 - 0.0045 16.9 1.4 0.91 9.4 0.0 3.7 3 1 1 4 4 4 1 AAA domain SbcCD_C PF13558.1 KNE01266.1 - 0.0055 16.6 0.1 6.9 6.6 0.1 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 KNE01266.1 - 0.006 16.0 0.7 6 6.2 0.1 3.2 3 1 0 3 3 3 0 AAA-like domain Dynamin_N PF00350.18 KNE01266.1 - 0.017 14.9 10.5 0.027 14.2 0.1 3.5 3 1 1 4 4 3 0 Dynamin family Pox_A32 PF04665.7 KNE01266.1 - 0.018 14.3 1.4 0.21 10.8 0.1 2.7 3 0 0 3 3 3 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.13 KNE01266.1 - 0.038 13.4 0.1 2.5 7.5 0.0 2.7 3 0 0 3 3 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 KNE01266.1 - 0.07 12.7 0.0 12 5.3 0.0 3.3 3 1 0 3 3 3 0 AAA domain AAA_5 PF07728.9 KNE01266.1 - 0.074 12.7 0.2 2.5 7.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 KNE01266.1 - 0.082 11.6 0.1 1.3 7.7 0.0 2.5 2 0 0 2 2 2 0 ArgK protein Lactamase_B_2 PF12706.2 KNE01267.1 - 2.6e-30 105.4 0.3 3.5e-30 104.9 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KNE01267.1 - 1.1e-16 60.9 0.0 1.6e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Romo1 PF10247.4 KNE01268.1 - 1.4e-28 98.8 11.3 1.9e-28 98.4 7.8 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 DUF1690 PF07956.6 KNE01269.1 - 7.7e-43 145.8 10.5 8.7e-43 145.6 7.3 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) DUF773 PF05600.7 KNE01269.1 - 0.0087 14.8 6.8 0.011 14.5 4.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF773) YqgF PF14639.1 KNE01269.1 - 0.01 15.4 1.4 0.013 15.0 1.0 1.2 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 DUF2321 PF10083.4 KNE01269.1 - 0.028 13.9 3.1 0.041 13.3 2.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) CHCH PF06747.8 KNE01269.1 - 0.077 12.9 0.2 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 CHCH domain LMBR1 PF04791.11 KNE01269.1 - 0.15 10.5 3.9 0.18 10.3 2.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3828 PF12883.2 KNE01269.1 - 0.63 9.9 5.0 3.8 7.4 3.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3828) TnpV PF14198.1 KNE01269.1 - 0.87 9.5 4.3 1.6 8.6 2.3 1.8 1 1 1 2 2 2 0 Transposon-encoded protein TnpV MbeB_N PF04837.7 KNE01269.1 - 2 8.5 9.1 7.9 6.6 0.9 2.7 2 1 0 2 2 2 0 MbeB-like, N-term conserved region ATP-synt_B PF00430.13 KNE01269.1 - 3.3 7.5 14.1 4.7 7.0 9.8 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF16 PF01519.11 KNE01269.1 - 3.7 7.8 8.7 6.7 6.9 6.0 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 UCH PF00443.24 KNE01270.1 - 1.5e-44 152.1 8.8 2.7e-44 151.2 6.1 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KNE01270.1 - 9.2e-14 51.5 13.3 6.8e-13 48.7 9.2 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 KNE01270.1 - 1.1e-09 37.5 0.8 2.4e-09 36.4 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin family Syntaxin_2 PF14523.1 KNE01270.1 - 0.29 11.1 7.3 0.37 10.8 3.2 2.5 2 0 0 2 2 2 0 Syntaxin-like protein DUF2361 PF10153.4 KNE01270.1 - 1.5 9.0 10.4 0.77 9.9 2.4 2.5 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2361) FliD_N PF02465.13 KNE01270.1 - 4.4 7.7 8.8 13 6.2 0.9 3.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Aldedh PF00171.17 KNE01271.1 - 5.2e-79 265.7 0.5 9.7e-79 264.8 0.0 1.6 2 0 0 2 2 2 1 Aldehyde dehydrogenase family LuxC PF05893.9 KNE01271.1 - 0.0016 17.2 0.9 0.0024 16.6 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) Abhydrolase_6 PF12697.2 KNE01272.1 - 3.2e-08 33.7 0.0 3.9e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNE01272.1 - 0.003 17.3 0.0 0.0049 16.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KNE01272.1 - 0.025 14.0 0.0 0.74 9.2 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.15 KNE01272.1 - 0.11 11.8 0.0 0.32 10.3 0.0 1.8 1 1 0 1 1 1 0 Putative esterase WD40 PF00400.27 KNE01273.1 - 1.4e-06 27.9 1.4 0.0088 15.8 0.0 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Nop14 PF04147.7 KNE01273.1 - 0.0011 17.0 8.2 0.0014 16.6 5.7 1.1 1 0 0 1 1 1 1 Nop14-like family TFIIIC_delta PF12657.2 KNE01273.1 - 0.041 13.5 0.2 0.24 11.0 0.1 2.3 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term RRN3 PF05327.6 KNE01274.1 - 4.6e-149 497.1 7.4 4.6e-149 497.1 5.2 2.1 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 DUF1539 PF07560.6 KNE01274.1 - 0.031 14.1 0.2 0.24 11.2 0.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) STE PF02200.11 KNE01278.1 - 2.1e-60 201.6 1.1 3.3e-60 201.0 0.8 1.3 1 0 0 1 1 1 1 STE like transcription factor CLASP_N PF12348.3 KNE01279.1 - 2e-77 259.6 16.4 6.3e-68 228.5 0.6 3.3 3 0 0 3 3 3 2 CLASP N terminal HEAT_2 PF13646.1 KNE01279.1 - 0.05 13.8 0.5 5 7.4 0.0 3.0 3 0 0 3 3 3 0 HEAT repeats Peptidase_C13 PF01650.13 KNE01280.1 - 4.7e-44 150.6 0.6 7.9e-44 149.8 0.4 1.3 1 0 0 1 1 1 1 Peptidase C13 family ResIII PF04851.10 KNE01281.1 - 1.8e-24 86.6 0.1 4.7e-24 85.2 0.1 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KNE01281.1 - 1.6e-13 50.3 0.1 5e-13 48.7 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KNE01281.1 - 3.4e-11 42.9 1.1 6.5e-11 42.0 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C_2 PF13307.1 KNE01281.1 - 0.0047 16.9 0.2 0.44 10.4 0.0 2.7 2 0 0 2 2 2 1 Helicase C-terminal domain SNF2_N PF00176.18 KNE01281.1 - 0.012 14.4 0.1 0.019 13.7 0.1 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF2075 PF09848.4 KNE01281.1 - 0.013 14.4 0.0 0.033 13.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 KNE01281.1 - 0.027 14.3 0.0 0.4 10.5 0.0 2.8 2 1 0 2 2 2 0 AAA domain Pol_alpha_B_N PF08418.5 KNE01282.1 - 2.4e-45 155.0 1.7 4.4e-45 154.2 1.2 1.4 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 KNE01282.1 - 7.9e-36 123.2 0.2 1.2e-35 122.7 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CPSase_sm_chain PF00988.17 KNE01282.1 - 0.18 11.3 0.0 0.39 10.2 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain La PF05383.12 KNE01283.1 - 1.9e-19 69.2 0.0 4e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 KNE01283.1 - 0.014 15.0 0.7 0.19 11.3 0.5 2.4 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNE01283.1 - 0.076 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2201_N PF13203.1 KNE01283.1 - 0.36 9.9 9.2 0.22 10.6 5.2 1.5 2 0 0 2 2 2 0 Putative metallopeptidase domain Ala_racemase_N PF01168.15 KNE01284.1 - 7.2e-44 149.9 0.0 8.5e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DHQS PF01959.11 KNE01284.1 - 0.012 14.2 0.1 0.031 12.9 0.0 1.7 2 0 0 2 2 2 0 3-dehydroquinate synthase (EC 4.6.1.3) Anoctamin PF04547.7 KNE01285.1 - 6.2e-76 255.8 7.1 8.5e-76 255.4 4.9 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel SH3_9 PF14604.1 KNE01286.1 - 1e-11 44.2 0.0 3.1e-11 42.6 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KNE01286.1 - 1.7e-10 40.1 0.1 1.7e-10 40.1 0.1 2.2 3 0 0 3 3 3 1 SH3 domain SH3_2 PF07653.12 KNE01286.1 - 3.1e-09 36.1 0.0 6.5e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain WD40 PF00400.27 KNE01287.1 - 4.3e-16 58.0 3.3 1.4e-08 34.2 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat CAP PF00188.21 KNE01289.1 - 4.7e-17 62.6 8.5 4.7e-17 62.6 5.9 2.7 2 1 0 2 2 2 1 Cysteine-rich secretory protein family Adaptin_N PF01602.15 KNE01290.1 - 4.5e-77 259.5 8.0 7.7e-76 255.4 5.6 2.0 1 1 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 KNE01290.1 - 3.8e-08 33.6 0.0 7.6e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Alpha_adaptin_C PF02296.11 KNE01290.1 - 3.8e-06 26.8 0.0 1.3e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain HEAT_2 PF13646.1 KNE01290.1 - 0.0058 16.8 0.0 0.48 10.7 0.0 3.7 3 2 0 3 3 3 1 HEAT repeats Mt_ATP-synt_D PF05873.7 KNE01291.1 - 1.4e-14 54.0 3.0 1.6e-14 53.8 2.1 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) EzrA PF06160.7 KNE01291.1 - 0.00088 17.5 3.2 0.022 12.9 2.0 2.0 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA DUF4547 PF15080.1 KNE01291.1 - 0.026 13.9 0.5 0.07 12.5 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4547) DUF2317 PF10079.4 KNE01291.1 - 0.044 12.3 2.7 0.058 12.0 1.9 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) MbeB_N PF04837.7 KNE01291.1 - 0.12 12.5 4.4 0.12 12.4 0.8 2.3 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Erf4 PF10256.4 KNE01292.1 - 0.12 12.2 0.4 0.18 11.6 0.3 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family SMC_hinge PF06470.8 KNE01293.1 - 0.0069 16.3 0.0 0.024 14.6 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain MFS_1 PF07690.11 KNE01298.1 - 5.3e-30 104.3 56.8 1.3e-28 99.7 17.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KNE01298.1 - 0.0036 17.2 7.1 0.091 12.8 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1228) DUF997 PF06196.7 KNE01298.1 - 2.3 7.8 10.5 2.9 7.4 4.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF997) BolA PF01722.13 KNE01299.1 - 1.5e-21 76.1 0.0 1.8e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein RhoGAP PF00620.22 KNE01300.1 - 8.6e-36 122.8 0.3 1.7e-35 121.9 0.2 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 KNE01300.1 - 4.5e-29 100.2 53.3 2e-11 43.7 8.2 4.6 4 0 0 4 4 4 4 LIM domain zf-C2H2_6 PF13912.1 KNE01300.1 - 0.021 14.7 0.7 0.021 14.7 0.5 5.1 4 1 1 5 5 5 0 C2H2-type zinc finger PIG-H PF10181.4 KNE01304.1 - 2e-22 78.5 0.1 3.5e-22 77.7 0.1 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Myb_DNA-binding PF00249.26 KNE01305.1 - 2e-05 24.5 0.1 5.9e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KNE01305.1 - 0.054 13.6 2.6 0.077 13.1 0.2 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain WD40 PF00400.27 KNE01306.1 - 2e-15 55.9 4.1 1.6e-05 24.5 0.1 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat TraH_2 PF06871.6 KNE01306.1 - 0.22 10.9 1.0 0.38 10.1 0.7 1.3 1 0 0 1 1 1 0 TraH_2 BLVR PF06375.6 KNE01306.1 - 1.4 8.7 16.1 0.27 11.0 8.7 1.6 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Hist_deacetyl PF00850.14 KNE01307.1 - 2.3e-96 322.7 0.0 3.3e-96 322.2 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 KNE01307.1 - 2.3e-45 154.2 1.1 4e-45 153.4 0.5 1.7 2 0 0 2 2 2 1 Arb2 domain Cytomega_UL20A PF05984.7 KNE01307.1 - 0.093 12.9 3.1 0.2 11.8 1.8 1.8 1 1 0 1 1 1 0 Cytomegalovirus UL20A protein Pkinase PF00069.20 KNE01309.1 - 7e-42 143.3 0.0 1.1e-41 142.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE01309.1 - 3e-27 95.3 0.0 4.3e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNE01309.1 - 0.0006 18.8 0.0 0.0012 17.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KNE01309.1 - 0.084 11.6 0.1 0.2 10.4 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 APH PF01636.18 KNE01309.1 - 0.2 11.3 0.1 0.45 10.2 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Nol1_Nop2_Fmu PF01189.12 KNE01310.1 - 1e-19 70.9 0.1 4e-19 69.0 0.0 1.9 1 1 0 1 1 1 1 NOL1/NOP2/sun family Iso_dh PF00180.15 KNE01311.1 - 1.3e-99 333.4 0.1 2.7e-99 332.4 0.1 1.4 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Transp_cyt_pur PF02133.10 KNE01313.1 - 7.9e-144 479.4 29.0 9.1e-144 479.2 20.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin GrpE PF01025.14 KNE01315.1 - 3.3e-51 173.1 12.3 7.6e-51 171.9 8.5 1.6 1 1 0 1 1 1 1 GrpE SspB PF04386.8 KNE01315.1 - 0.013 15.0 2.0 0.038 13.6 1.4 1.7 1 0 0 1 1 1 0 Stringent starvation protein B Exonuc_VII_L PF02601.10 KNE01315.1 - 0.3 10.2 7.2 0.37 9.9 5.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit GET2 PF08690.5 KNE01315.1 - 1.3 8.1 7.5 1.7 7.8 5.2 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 ARD PF03079.9 KNE01315.1 - 6.6 6.6 8.2 18 5.2 5.5 1.8 1 1 1 2 2 2 0 ARD/ARD' family DUF4407 PF14362.1 KNE01315.1 - 6.8 5.5 8.2 8.1 5.2 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Bap31 PF05529.7 KNE01315.1 - 6.9 6.0 15.3 0.44 9.9 6.7 1.7 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Abhydrolase_6 PF12697.2 KNE01316.1 - 1.3e-15 57.9 0.0 4e-15 56.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNE01316.1 - 3e-09 36.7 0.0 4.9e-07 29.5 0.0 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNE01316.1 - 8.5e-06 25.5 0.1 8.4e-05 22.3 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KNE01316.1 - 0.0027 17.1 0.0 0.012 15.0 0.0 2.0 2 0 0 2 2 2 1 Putative esterase Abhydrolase_2 PF02230.11 KNE01316.1 - 0.0076 15.7 0.0 0.089 12.2 0.0 2.3 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase FSH1 PF03959.8 KNE01316.1 - 0.011 15.1 0.0 0.83 9.0 0.0 2.4 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Sulfate_transp PF00916.15 KNE01317.1 - 2.5e-48 164.5 10.3 2.5e-48 164.5 7.1 2.0 1 1 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KNE01317.1 - 3.6e-22 77.8 8.0 1.9e-21 75.5 5.5 2.4 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KNE01317.1 - 6.4e-17 61.0 0.1 1.3e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KNE01317.1 - 0.082 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 STAS domain Oxidored-like PF09791.4 KNE01319.1 - 9.3e-27 92.2 2.9 1.7e-26 91.4 2.0 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DPM3 PF08285.6 KNE01320.1 - 1e-34 118.2 0.1 1.2e-34 118.0 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF3180 PF11377.3 KNE01320.1 - 0.13 12.0 0.5 0.23 11.2 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3180) Tau95 PF09734.4 KNE01321.1 - 5.5e-62 209.8 7.3 8.4e-62 209.2 5.0 1.3 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit NOA36 PF06524.7 KNE01321.1 - 6.9 5.8 12.8 4.7 6.3 6.5 2.0 2 0 0 2 2 2 0 NOA36 protein Ldh_1_N PF00056.18 KNE01322.1 - 6.5e-44 149.1 0.5 9.9e-44 148.5 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KNE01322.1 - 5.2e-42 143.5 0.0 8.9e-42 142.7 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain NAD_binding_10 PF13460.1 KNE01322.1 - 0.0031 17.5 0.1 0.0069 16.4 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KNE01322.1 - 0.0045 15.7 0.0 0.0068 15.1 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 KNE01322.1 - 0.078 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Glyco_hydro_4 PF02056.11 KNE01322.1 - 0.1 11.9 0.9 2.5 7.3 0.1 2.8 2 1 1 3 3 3 0 Family 4 glycosyl hydrolase zf-C2H2 PF00096.21 KNE01323.1 - 3.9e-08 33.1 12.4 2.1e-05 24.5 1.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNE01323.1 - 1.8e-07 30.9 12.1 0.0034 17.5 2.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KNE01323.1 - 4.2e-06 26.7 19.6 2.3e-05 24.4 2.1 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 KNE01323.1 - 0.00023 21.2 1.4 0.069 13.3 0.4 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KNE01323.1 - 0.2 11.8 4.0 12 6.1 0.5 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KNE01323.1 - 1.6 8.9 7.3 5 7.2 0.9 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Aminotran_1_2 PF00155.16 KNE01324.1 - 8.9e-65 218.9 0.0 1e-64 218.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3458 PF11940.3 KNE01324.1 - 0.11 11.3 0.0 0.22 10.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) NIF PF03031.13 KNE01326.1 - 2.9e-46 157.0 0.1 4e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase zinc_ribbon_6 PF14599.1 KNE01328.1 - 3.7e-24 84.3 2.1 3.7e-24 84.3 1.5 3.5 2 1 0 2 2 2 1 Zinc-ribbon zf-CHY PF05495.7 KNE01328.1 - 5.5e-14 52.0 21.5 5.5e-14 52.0 14.9 4.6 3 1 0 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.1 KNE01328.1 - 1e-08 34.8 7.8 1e-08 34.8 5.4 5.3 3 2 2 5 5 5 1 Ring finger domain zf-C3HC4_3 PF13920.1 KNE01328.1 - 8e-07 28.6 10.2 8e-07 28.6 7.0 5.9 3 2 3 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KNE01328.1 - 2.2e-06 27.5 7.8 2.2e-06 27.5 5.4 5.7 5 2 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNE01328.1 - 7.4e-05 22.3 11.8 7.4e-05 22.3 8.2 6.2 3 2 3 6 6 6 1 zinc-RING finger domain PRP21_like_P PF12230.3 KNE01329.1 - 1.2e-54 185.2 17.5 1.2e-54 185.2 12.1 2.4 3 0 0 3 3 3 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 KNE01329.1 - 3.8e-24 84.1 2.9 2.6e-16 58.9 0.1 2.8 2 1 0 2 2 2 2 Surp module Ribosomal_S6e PF01092.14 KNE01330.1 - 5.4e-62 207.0 0.1 8.7e-62 206.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S6e Cadherin_C PF01049.12 KNE01330.1 - 0.011 15.7 0.3 0.02 14.9 0.2 1.4 1 0 0 1 1 1 0 Cadherin cytoplasmic region Glyoxalase_2 PF12681.2 KNE01330.1 - 0.11 13.1 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase-like domain SRF-TF PF00319.13 KNE01331.1 - 1.4e-21 75.4 0.0 2.6e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Tim54 PF11711.3 KNE01331.1 - 6.7 5.2 13.5 0.042 12.4 1.6 2.3 1 1 1 3 3 3 0 Inner membrane protein import complex subunit Tim54 Sec16_C PF12931.2 KNE01333.1 - 6.1e-63 213.2 0.0 1e-62 212.4 0.0 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 KNE01333.1 - 6.8e-16 58.3 0.0 2.4e-15 56.5 0.0 2.1 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region RRM_1 PF00076.17 KNE01334.1 - 2.1e-89 293.1 4.9 4.6e-22 77.4 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNE01334.1 - 1.3e-60 201.2 0.6 1.6e-15 56.8 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNE01334.1 - 4.2e-43 144.9 0.1 2e-10 40.3 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KNE01334.1 - 7.7e-27 92.7 1.0 1.9e-26 91.5 0.1 2.0 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 KNE01334.1 - 8.8e-09 35.1 7.3 0.011 15.5 0.6 4.4 3 1 1 4 4 4 3 RNA binding motif Limkain-b1 PF11608.3 KNE01334.1 - 1.7e-05 24.5 1.8 0.014 15.1 0.1 4.0 4 0 0 4 4 4 1 Limkain b1 YflT PF11181.3 KNE01334.1 - 0.00017 21.6 3.4 0.18 11.9 0.7 3.8 3 0 0 3 3 3 1 Heat induced stress protein YflT Nup35_RRM_2 PF14605.1 KNE01334.1 - 0.00039 20.1 0.1 8.4 6.2 0.0 4.0 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.6 KNE01334.1 - 0.00094 18.6 1.8 2.9 7.4 0.0 3.5 3 0 0 3 3 3 2 Ribonuclease B OB domain DUF4078 PF13300.1 KNE01334.1 - 0.072 13.2 9.7 0.062 13.4 1.4 3.3 3 1 0 3 3 2 0 Domain of unknown function (DUF4078) CbiG_mid PF11761.3 KNE01334.1 - 0.078 13.2 0.2 1.1 9.4 0.0 2.9 4 0 0 4 4 4 0 Cobalamin biosynthesis central region GIY-YIG PF01541.19 KNE01334.1 - 0.39 11.1 2.2 1.9 8.8 0.4 2.4 2 0 0 2 2 2 0 GIY-YIG catalytic domain PAT1 PF09770.4 KNE01334.1 - 0.52 8.4 11.7 0.79 7.8 8.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glyco_transf_20 PF00982.16 KNE01335.1 - 3.4e-153 510.5 0.3 4.2e-153 510.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KNE01335.1 - 5.6e-76 254.5 0.0 1e-75 253.6 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Abhydrolase_6 PF12697.2 KNE01337.1 - 9e-16 58.4 0.0 1.3e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNE01337.1 - 6.8e-15 55.2 0.0 1e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNE01337.1 - 4.4e-06 26.5 0.0 1.4e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 KNE01337.1 - 0.0044 16.7 0.0 0.0069 16.1 0.0 1.2 1 0 0 1 1 1 1 Cutinase DUF915 PF06028.6 KNE01337.1 - 0.035 13.1 0.0 0.072 12.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF726 PF05277.7 KNE01337.1 - 0.07 12.0 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Arrestin_C PF02752.17 KNE01338.1 - 5.9e-19 68.5 0.5 2.1e-16 60.2 0.1 3.0 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KNE01338.1 - 4.3e-11 42.8 0.9 3.9e-07 30.0 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Sec62 PF03839.11 KNE01339.1 - 1.2e-57 194.8 1.0 1.2e-57 194.8 0.7 1.6 1 1 1 2 2 2 1 Translocation protein Sec62 Ca_hom_mod PF14798.1 KNE01339.1 - 0.2 10.5 0.6 0.28 10.1 0.4 1.1 1 0 0 1 1 1 0 Calcium homeostasis modulator WD40 PF00400.27 KNE01340.1 - 2.6e-05 23.9 2.1 0.017 14.9 0.0 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Spo12 PF05032.7 KNE01341.1 - 0.049 13.2 0.1 0.078 12.6 0.1 1.2 1 0 0 1 1 1 0 Spo12 family ECH_C PF13766.1 KNE01342.1 - 7e-23 81.0 0.0 1.4e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KNE01342.1 - 3e-22 78.9 0.0 9.4e-22 77.3 0.0 1.7 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family Pec_lyase_N PF04431.8 KNE01342.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Pectate lyase, N terminus Actin PF00022.14 KNE01343.1 - 4.6e-64 216.2 0.0 2.1e-53 181.1 0.0 2.4 2 1 0 2 2 2 2 Actin DUF733 PF05306.6 KNE01345.1 - 0.049 13.9 0.8 0.049 13.9 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF733) Peptidase_C97 PF05903.9 KNE01347.1 - 2.4e-38 131.2 0.0 2.7e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain AAA_10 PF12846.2 KNE01347.1 - 0.046 13.1 0.0 0.054 12.9 0.0 1.0 1 0 0 1 1 1 0 AAA-like domain LRAT PF04970.8 KNE01347.1 - 0.048 13.6 0.2 0.071 13.0 0.1 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase SAYSvFN PF10260.4 KNE01347.1 - 0.1 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) EST1_DNA_bind PF10373.4 KNE01348.1 - 4.7e-26 91.6 3.0 4.7e-26 91.6 2.1 2.3 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 KNE01348.1 - 1.4e-10 41.2 1.1 1.4e-10 41.2 0.8 3.0 3 0 0 3 3 3 1 Telomerase activating protein Est1 FA_desaturase PF00487.19 KNE01349.1 - 7.2e-30 104.2 10.0 1.2e-29 103.5 7.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 KNE01349.1 - 3.6e-18 64.5 0.2 6.7e-18 63.6 0.1 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) tRNA-synt_His PF13393.1 KNE01350.1 - 6.4e-38 130.5 0.0 3e-31 108.6 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 KNE01350.1 - 1.1e-17 64.1 0.0 2.2e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KNE01350.1 - 1.3e-10 41.1 0.0 2.7e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 KNE01350.1 - 2.1e-05 23.4 0.0 6.8e-05 21.7 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.2 KNE01350.1 - 0.011 14.8 0.1 0.028 13.5 0.0 1.6 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs tRNA-synt_2d PF01409.15 KNE01350.1 - 0.052 12.7 0.0 0.084 12.0 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Pdase_C33_assoc PF14756.1 KNE01350.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase_C33-associated domain Ribosomal_60s PF00428.14 KNE01350.1 - 3.1 8.2 9.9 0.095 13.1 0.4 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein IDO PF01231.13 KNE01351.1 - 1.2e-157 524.7 0.0 1.4e-157 524.5 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase FAST_1 PF06743.10 KNE01351.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 BAR PF03114.13 KNE01352.1 - 2.6e-57 193.9 8.4 3.5e-57 193.5 5.8 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KNE01352.1 - 9.6e-15 53.7 0.1 9.6e-15 53.7 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KNE01352.1 - 7.7e-14 51.0 0.1 1.3e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KNE01352.1 - 2.6e-09 36.4 0.0 5.2e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FAM104 PF15434.1 KNE01352.1 - 0.089 12.9 0.2 8.5 6.6 0.0 2.6 2 0 0 2 2 2 0 Family 104 DUF755 PF05501.6 KNE01352.1 - 1.3 9.0 8.1 0.46 10.5 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Zn_clus PF00172.13 KNE01355.1 - 0.008 16.0 9.8 0.012 15.5 6.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 KNE01356.1 - 2e-25 90.0 0.0 2.4e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNE01356.1 - 1.3e-11 44.4 0.0 2e-10 40.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNE01356.1 - 1.4e-06 28.1 0.0 3.1e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 KNE01356.1 - 0.0081 14.9 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Thioesterase PF00975.15 KNE01356.1 - 0.028 14.6 0.0 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 Thioesterase domain PMP1_2 PF08114.6 KNE01357.1 - 2.7e-12 45.9 0.4 2.9e-12 45.8 0.3 1.1 1 0 0 1 1 1 1 ATPase proteolipid family PSI_PSAK PF01241.13 KNE01357.1 - 0.042 13.8 0.3 0.042 13.8 0.2 1.0 1 0 0 1 1 1 0 Photosystem I psaG / psaK DUF1049 PF06305.6 KNE01357.1 - 0.067 12.6 0.3 0.073 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF4006 PF13179.1 KNE01357.1 - 0.28 10.7 1.2 0.32 10.5 0.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF4006) P12 PF12669.2 KNE01357.1 - 1 9.6 3.1 1.1 9.4 2.2 1.1 1 0 0 1 1 1 0 Virus attachment protein p12 family PsbX PF06596.6 KNE01357.1 - 8.5 6.1 7.0 23 4.7 4.8 1.7 1 1 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) RCR PF12273.3 KNE01361.1 - 1.6e-09 38.4 1.9 2.3e-09 37.9 1.3 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF1183 PF06682.7 KNE01361.1 - 0.0021 17.7 0.6 0.0026 17.4 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) MFS_1 PF07690.11 KNE01361.1 - 0.044 12.4 0.0 0.049 12.3 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily BatD PF13584.1 KNE01361.1 - 0.052 12.1 0.2 0.064 11.8 0.2 1.1 1 0 0 1 1 1 0 Oxygen tolerance MFS_1 PF07690.11 KNE01362.1 - 1.9e-34 118.9 14.2 1.2e-25 90.0 0.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KNE01362.1 - 8.1e-09 34.5 3.0 8.1e-09 34.5 2.0 2.9 3 1 1 4 4 4 1 Sugar (and other) transporter MFS_2 PF13347.1 KNE01362.1 - 3.1e-05 22.5 3.6 3.1e-05 22.5 2.5 3.6 3 1 0 3 3 3 1 MFS/sugar transport protein UNC-93 PF05978.11 KNE01362.1 - 0.00067 19.1 0.8 0.00067 19.1 0.6 2.2 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 TRI12 PF06609.8 KNE01362.1 - 0.0043 15.3 1.5 0.0047 15.1 0.3 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KNE01363.1 - 6.5e-22 77.7 28.1 8.4e-17 60.9 3.6 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KNE01363.1 - 1.5e-07 30.3 2.5 1.5e-07 30.3 1.7 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KNE01363.1 - 0.00015 20.2 19.2 0.00046 18.7 1.5 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein 7TM_GPCR_Sri PF10327.4 KNE01363.1 - 0.07 12.0 5.0 0.057 12.3 0.3 2.6 2 1 1 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Sri Ribonucleas_3_2 PF11469.3 KNE01365.1 - 0.089 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Ribonuclease III Fungal_trans PF04082.13 KNE01367.1 - 2.6e-16 59.2 0.1 4.7e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNE01367.1 - 4.4e-08 32.8 11.5 7.3e-08 32.2 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GoLoco PF02188.12 KNE01367.1 - 0.12 11.7 0.2 0.54 9.6 0.1 2.2 2 0 0 2 2 2 0 GoLoco motif Ribosomal_L10 PF00466.15 KNE01368.1 - 5.7e-28 96.7 0.7 1.4e-27 95.5 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 KNE01368.1 - 1.6e-20 73.2 9.7 5.4e-20 71.5 5.3 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein S19 PF06756.6 KNE01368.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Chorion protein S19 C-terminal Ribosomal_S16 PF00886.14 KNE01370.1 - 4.4e-24 83.9 0.1 6.7e-24 83.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 NUC173 PF08161.7 KNE01371.1 - 4.4e-76 254.6 1.1 1.2e-71 240.1 0.1 2.8 2 0 0 2 2 2 2 NUC173 domain Ipi1_N PF12333.3 KNE01371.1 - 0.016 15.1 1.4 9.5 6.2 0.1 4.4 3 1 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.17 KNE01371.1 - 0.024 14.6 0.0 18 5.7 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat L51_S25_CI-B8 PF05047.11 KNE01372.1 - 8.1e-09 35.0 0.0 1.1e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LigB PF02900.13 KNE01373.1 - 4.6e-33 114.3 0.0 6.5e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase BTB PF00651.26 KNE01376.1 - 7e-12 45.3 0.1 4.6e-05 23.3 0.0 3.5 3 0 0 3 3 3 2 BTB/POZ domain Ank_5 PF13857.1 KNE01376.1 - 2.3e-05 24.4 0.0 5.6e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 KNE01376.1 - 2.3e-05 23.9 0.4 8.3e-05 22.2 0.3 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 KNE01376.1 - 0.0009 19.5 0.0 0.0025 18.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KNE01376.1 - 0.0031 17.9 0.4 0.0076 16.7 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) SPRY PF00622.23 KNE01376.1 - 0.052 13.6 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 SPRY domain DcpS_C PF11969.3 KNE01377.1 - 3.4e-29 101.4 0.6 6.4e-29 100.5 0.1 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 KNE01377.1 - 6.8e-29 100.4 0.4 1.2e-28 99.6 0.3 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal HIT PF01230.18 KNE01377.1 - 0.22 12.0 1.4 0.57 10.7 0.1 2.2 2 1 0 2 2 2 0 HIT domain DEAD PF00270.24 KNE01378.1 - 2.3e-39 134.6 0.1 3.9e-39 133.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KNE01378.1 - 1.8e-18 65.8 0.1 4.4e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KNE01378.1 - 2.5e-17 62.4 0.0 5.2e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sin_N PF04801.8 KNE01379.1 - 1.6e-14 53.6 0.0 8e-14 51.3 0.0 1.8 1 1 0 1 1 1 1 Sin-like protein conserved region MF_alpha PF04648.7 KNE01380.1 - 1.4e-06 28.0 30.9 0.47 10.7 0.4 5.3 5 0 0 5 5 5 5 Yeast mating factor alpha hormone MF_alpha_N PF05436.6 KNE01380.1 - 0.00081 19.0 0.4 0.0021 17.6 0.3 1.7 1 1 0 1 1 1 1 Mating factor alpha precursor N-terminus DUF2227 PF09988.4 KNE01380.1 - 9.1 5.8 7.5 1.9e+02 1.5 0.0 4.4 5 0 0 5 5 5 0 Uncharacterized metal-binding protein (DUF2227) UCH_1 PF13423.1 KNE01384.1 - 1.4e-38 133.0 0.1 2.2e-38 132.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 KNE01384.1 - 1e-25 90.9 0.0 2.3e-25 89.7 0.0 1.6 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 KNE01384.1 - 7.9e-07 28.4 0.0 6.6e-06 25.4 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TCO89 PF10452.4 KNE01385.1 - 1.9e-15 56.8 46.0 3e-08 33.0 3.4 3.2 2 2 1 3 3 3 2 TORC1 subunit TCO89 Ribosomal_L28 PF00830.14 KNE01388.1 - 3.5e-09 36.3 0.9 3.5e-09 36.3 0.6 1.8 2 0 0 2 2 2 1 Ribosomal L28 family Sec66 PF09802.4 KNE01388.1 - 0.016 14.6 0.1 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 Endomucin PF07010.7 KNE01390.1 - 0.046 13.0 0.1 0.05 12.9 0.1 1.0 1 0 0 1 1 1 0 Endomucin DUF1616 PF07760.6 KNE01390.1 - 0.057 12.5 0.0 0.057 12.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) DUF4349 PF14257.1 KNE01390.1 - 0.13 11.4 0.2 0.16 11.2 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Pkinase PF00069.20 KNE01392.1 - 6e-72 241.9 0.0 8e-72 241.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE01392.1 - 3e-30 105.1 0.0 4.5e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KNE01392.1 - 3.6e-14 53.0 1.8 1e-13 51.5 1.2 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KNE01392.1 - 7e-10 38.3 0.0 1.5e-09 37.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 KNE01392.1 - 7.3e-05 22.5 0.0 0.00043 20.0 0.0 2.2 1 1 0 1 1 1 1 C2 domain APH PF01636.18 KNE01392.1 - 0.063 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KNE01392.1 - 0.082 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 KNE01392.1 - 0.089 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YppG PF14179.1 KNE01394.1 - 0.028 15.0 13.0 0.028 15.0 9.0 2.0 2 1 0 2 2 2 0 YppG-like protein GATase_4 PF13230.1 KNE01395.1 - 3.2e-17 62.1 0.0 1e-16 60.4 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 KNE01395.1 - 5.7e-11 42.4 0.0 1.2e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KNE01395.1 - 6.5e-10 38.2 0.0 3e-08 32.7 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 KNE01395.1 - 0.049 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase domain SAPS PF04499.10 KNE01396.1 - 3.2e-179 596.5 0.8 3.2e-179 596.5 0.6 3.6 3 1 1 4 4 4 1 SIT4 phosphatase-associated protein Ribosomal_L21p PF00829.16 KNE01398.1 - 0.061 13.4 0.1 0.075 13.1 0.1 1.1 1 0 0 1 1 1 0 Ribosomal prokaryotic L21 protein Pkinase PF00069.20 KNE01399.1 - 1.9e-70 236.9 0.0 3.2e-70 236.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE01399.1 - 2.1e-48 164.6 0.0 3.8e-48 163.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNE01399.1 - 4.9e-09 35.5 0.1 4.1e-06 25.9 0.0 2.9 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 KNE01399.1 - 0.042 12.8 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sfi1 PF08457.5 KNE01400.1 - 5.9e-36 124.0 80.3 4.6e-33 114.4 45.1 2.3 1 1 1 2 2 2 2 Sfi1 spindle body protein HTH_23 PF13384.1 KNE01400.1 - 0.035 13.7 0.1 0.26 10.9 0.1 2.6 1 0 0 1 1 1 0 Homeodomain-like domain Glyco_transf_22 PF03901.12 KNE01401.1 - 6.4e-37 127.5 10.9 9e-37 127.0 7.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family COX15-CtaA PF02628.10 KNE01401.1 - 0.34 9.7 6.9 2.5 6.8 4.8 2.1 1 1 0 1 1 1 0 Cytochrome oxidase assembly protein EB1 PF03271.12 KNE01402.1 - 0.0014 18.6 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 EB1-like C-terminal motif Rop PF01815.11 KNE01402.1 - 0.12 11.8 1.0 0.14 11.6 0.3 1.4 1 1 0 1 1 1 0 Rop protein cobW PF02492.14 KNE01403.1 - 4.9e-41 140.1 0.7 6.6e-41 139.6 0.5 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KNE01403.1 - 1.3e-06 28.0 0.0 2.8e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MMR_HSR1 PF01926.18 KNE01403.1 - 0.00045 20.1 0.1 0.0016 18.4 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 KNE01403.1 - 0.0054 16.2 0.6 0.017 14.6 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KNE01403.1 - 0.0067 16.7 1.1 0.023 15.0 0.7 2.2 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 KNE01403.1 - 0.015 14.5 0.1 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain ABC_tran PF00005.22 KNE01403.1 - 0.016 15.4 0.3 0.099 12.9 0.0 2.2 2 0 0 2 2 2 0 ABC transporter MobB PF03205.9 KNE01403.1 - 0.022 14.4 0.1 0.077 12.6 0.0 2.0 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KNE01403.1 - 0.031 14.4 0.4 0.58 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KNE01403.1 - 0.031 14.1 0.0 0.092 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KNE01403.1 - 0.079 13.7 0.9 0.53 11.1 0.7 2.4 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KNE01403.1 - 0.15 12.3 8.7 1.1 9.5 4.9 2.7 1 1 1 2 2 2 0 AAA domain Tim54 PF11711.3 KNE01404.1 - 1.2e-135 451.9 3.2 1.8e-135 451.4 2.2 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF4351 PF14261.1 KNE01404.1 - 0.029 14.2 0.1 4.1 7.3 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) ELFV_dehydrog PF00208.16 KNE01405.1 - 1.7e-85 286.5 6.5 2e-85 286.2 4.5 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KNE01405.1 - 1.3e-45 154.1 0.0 2.2e-45 153.4 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Transposase_24 PF03004.9 KNE01406.1 - 0.0075 16.1 0.2 0.01 15.7 0.1 1.1 1 0 0 1 1 1 1 Plant transposase (Ptta/En/Spm family) zf-Nse PF11789.3 KNE01407.1 - 5.4e-19 67.4 0.1 1.2e-18 66.3 0.0 1.6 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 KNE01407.1 - 2.1e-05 24.4 0.0 4.5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain TALPID3 PF15324.1 KNE01407.1 - 0.051 10.9 0.1 0.058 10.7 0.1 1.1 1 0 0 1 1 1 0 Hedgehog signalling target zf-RING_UBOX PF13445.1 KNE01407.1 - 0.06 13.0 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Phosphodiest PF01663.17 KNE01408.1 - 1e-81 275.0 0.7 1.4e-81 274.6 0.5 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KNE01408.1 - 0.0087 15.2 0.1 0.27 10.3 0.0 2.3 2 0 0 2 2 2 1 Sulfatase Sda PF08970.5 KNE01408.1 - 0.089 12.2 0.1 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Sporulation inhibitor A NIF3 PF01784.13 KNE01409.1 - 5.2e-52 176.8 0.0 6.3e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) SPA PF08616.5 KNE01412.1 - 0.13 11.9 0.1 8.2 6.1 0.0 2.2 2 0 0 2 2 2 0 Stabilization of polarity axis DUF4259 PF14078.1 KNE01413.1 - 0.65 10.4 6.1 0.76 10.2 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) HIG_1_N PF04588.8 KNE01414.1 - 5.8e-20 70.7 0.2 9.5e-20 70.0 0.1 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region PEARLI-4 PF05278.7 KNE01414.1 - 0.14 11.5 8.4 0.19 11.0 5.8 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Cytadhesin_P30 PF07271.6 KNE01414.1 - 0.18 11.0 1.4 1 8.5 1.0 1.9 1 1 0 1 1 1 0 Cytadhesin P30/P32 DUF4485 PF14846.1 KNE01414.1 - 0.28 10.9 2.3 0.4 10.4 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) DUF972 PF06156.8 KNE01414.1 - 0.73 10.2 4.7 1.1 9.6 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ChAPs PF09295.5 KNE01416.1 - 5.2e-146 486.4 0.6 6.7e-146 486.0 0.4 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 KNE01416.1 - 4e-08 33.4 1.5 0.00098 19.4 0.0 2.8 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KNE01416.1 - 3.8e-07 29.6 0.8 0.00015 21.3 0.0 3.3 2 1 0 3 3 3 1 TPR repeat TPR_16 PF13432.1 KNE01416.1 - 4e-06 27.3 0.2 3.5e-05 24.3 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KNE01416.1 - 9e-05 22.5 1.9 0.0053 16.8 0.2 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KNE01416.1 - 0.00013 21.5 0.7 0.65 9.9 0.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KNE01416.1 - 0.00017 21.2 1.2 0.57 10.2 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KNE01416.1 - 0.0003 21.1 2.8 0.11 13.2 0.2 4.3 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KNE01416.1 - 0.042 13.8 1.0 0.94 9.4 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat PPR_3 PF13812.1 KNE01416.1 - 0.08 13.2 0.1 25 5.4 0.0 3.4 3 0 0 3 3 3 0 Pentatricopeptide repeat domain TFIID-31kDa PF02291.10 KNE01417.1 - 1.6e-48 163.7 0.0 2.1e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 KNE01417.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.6 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TPK_catalytic PF04263.11 KNE01418.1 - 2.4e-20 72.3 0.0 6.6e-19 67.6 0.0 2.1 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 KNE01418.1 - 1.7e-12 46.8 0.4 2.8e-12 46.1 0.3 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain DUF1713 PF08213.6 KNE01419.1 - 4.9e-09 35.6 20.4 6.9e-09 35.1 14.1 1.2 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Vel1p PF10339.4 KNE01419.1 - 0.012 14.7 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 Yeast-specific zinc responsive Ham1p_like PF01725.11 KNE01420.1 - 6.6e-54 182.1 0.0 7.5e-54 181.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DUF3602 PF12223.3 KNE01421.1 - 3.7e-30 104.1 18.9 9e-20 70.8 0.8 3.7 1 1 3 4 4 4 4 Protein of unknown function (DUF3602) DUF3484 PF11983.3 KNE01421.1 - 0.097 13.5 1.9 0.78 10.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3484) YadA_head PF05658.9 KNE01421.1 - 0.17 12.2 4.0 0.29 11.4 2.4 1.7 1 1 0 1 1 1 0 Head domain of trimeric autotransporter adhesin DUF1190 PF06693.6 KNE01421.1 - 0.33 10.9 9.4 1.3 9.1 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1190) DUF4407 PF14362.1 KNE01421.1 - 0.59 9.0 2.2 2.7 6.8 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF202 PF02656.10 KNE01424.1 - 1.9 8.7 4.5 2.3 8.5 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Fcf1 PF04900.7 KNE01426.1 - 1.2e-38 131.2 0.1 1.2e-38 131.2 0.1 1.6 2 0 0 2 2 2 1 Fcf1 Metallophos PF00149.23 KNE01427.1 - 2.7e-05 23.6 3.2 2.7e-05 23.6 2.2 2.4 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KNE01427.1 - 0.0011 18.8 0.2 0.0049 16.7 0.2 2.1 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain SBF PF01758.11 KNE01430.1 - 1.2e-51 174.8 12.0 1.2e-51 174.8 8.3 1.9 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF3464 PF11947.3 KNE01430.1 - 0.2 11.1 0.3 0.55 9.6 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) TFIIF_alpha PF05793.7 KNE01431.1 - 0.13 10.6 5.6 0.14 10.5 3.9 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Glyco_tran_28_C PF04101.11 KNE01432.1 - 5.7e-24 84.6 0.0 6.9e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KNE01432.1 - 1.2e-07 31.2 0.0 1.4e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 Glyco_trans_1_4 PF13692.1 KNE01432.1 - 0.0046 17.0 0.0 0.0058 16.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Hydrolase_6 PF13344.1 KNE01432.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase TFIID-18kDa PF02269.11 KNE01433.1 - 4.2e-20 71.3 0.1 6.3e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 KNE01433.1 - 0.00085 19.3 0.0 0.0084 16.2 0.0 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF1931 PF09123.6 KNE01433.1 - 0.0018 18.2 0.0 0.003 17.5 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1931) Bromo_TP PF07524.8 KNE01433.1 - 0.0074 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.18 KNE01433.1 - 0.0093 16.0 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 KNE01433.1 - 0.076 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinetochore component CENP-S DUF1639 PF07797.9 KNE01433.1 - 1.5 8.2 6.0 16 4.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) PMT PF02366.13 KNE01436.1 - 2.1e-76 256.5 17.0 4.9e-76 255.3 11.8 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KNE01436.1 - 8.8e-54 181.9 1.0 1.7e-53 180.9 0.7 1.5 1 0 0 1 1 1 1 MIR domain Ins145_P3_rec PF08709.6 KNE01436.1 - 4.8e-05 22.4 0.1 9.6e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor Lactamase_B PF00753.22 KNE01439.1 - 1.5e-26 93.2 1.9 2e-26 92.8 1.3 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KNE01439.1 - 0.00021 20.9 3.3 0.00069 19.2 2.3 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.15 KNE01439.1 - 0.033 13.4 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Y_phosphatase2 PF03162.8 KNE01440.1 - 8.5e-43 145.5 0.2 6.3e-41 139.4 0.1 2.0 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 KNE01440.1 - 7e-07 29.6 0.0 1e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF2784 PF10861.3 KNE01440.1 - 0.06 13.1 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF2784) Vhr1 PF04001.8 KNE01441.1 - 4e-44 148.4 5.2 8.1e-44 147.4 3.6 1.5 1 0 0 1 1 1 1 Transcription factor Vhr1 DUF4246 PF14033.1 KNE01442.1 - 6.1e-128 427.5 1.1 2.8e-127 425.4 0.8 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 KNE01442.1 - 0.0019 18.4 0.0 0.0041 17.3 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase DUF3354 PF11834.3 KNE01442.1 - 0.0021 17.6 0.0 0.16 11.6 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3354) KRAB PF01352.22 KNE01442.1 - 0.015 14.7 0.5 0.035 13.5 0.4 1.5 1 0 0 1 1 1 0 KRAB box 2OG-FeII_Oxy_3 PF13640.1 KNE01442.1 - 0.043 14.3 0.0 0.16 12.4 0.0 2.0 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Imm15 PF15590.1 KNE01442.1 - 0.048 12.7 0.8 0.13 11.3 0.5 1.7 1 0 0 1 1 1 0 Immunity protein 15 DUF3958 PF13125.1 KNE01442.1 - 1 9.3 6.4 4.6 7.2 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) Arginosuc_synth PF00764.14 KNE01444.1 - 9.4e-159 528.5 0.0 1.1e-158 528.3 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 KNE01444.1 - 1.6e-05 24.5 0.0 2.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 KNE01444.1 - 4.7e-05 22.7 0.0 7.4e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 KNE01444.1 - 0.001 17.7 0.1 0.0016 17.0 0.1 1.3 1 0 0 1 1 1 1 tRNA methyl transferase DUF2422 PF10337.4 KNE01445.1 - 4.8e-101 338.8 6.7 1.2e-100 337.4 3.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 KNE01445.1 - 6.6e-60 202.5 1.0 5.7e-59 199.5 0.2 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 KNE01445.1 - 2.8e-08 33.7 11.6 2.8e-08 33.7 8.0 3.5 3 1 1 4 4 4 1 Fusaric acid resistance protein-like Viral_DNA_Zn_bi PF03728.8 KNE01445.1 - 0.00076 19.5 0.0 0.0018 18.4 0.0 1.6 1 0 0 1 1 1 1 Viral DNA-binding protein, zinc binding domain HALZ PF02183.13 KNE01445.1 - 0.01 15.5 1.9 0.36 10.5 2.3 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper HTH_26 PF13443.1 KNE01445.1 - 0.07 13.3 0.0 0.67 10.2 0.0 2.5 2 1 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Cupin_8 PF13621.1 KNE01446.1 - 1.3e-09 37.9 0.0 2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain PHD PF00628.24 KNE01446.1 - 2.8e-07 30.1 8.8 5e-07 29.3 6.1 1.4 1 0 0 1 1 1 1 PHD-finger JmjC PF02373.17 KNE01446.1 - 4.3e-05 23.7 0.0 0.0001 22.5 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 KNE01446.1 - 0.0064 15.7 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Terminase_GpA PF05876.7 KNE01446.1 - 0.073 11.4 1.3 0.12 10.7 0.9 1.3 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Cupin_1 PF00190.17 KNE01446.1 - 0.13 11.7 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Cupin DUF1423 PF07227.6 KNE01446.1 - 0.26 9.9 4.0 0.51 8.9 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) PHD_2 PF13831.1 KNE01446.1 - 0.33 10.2 4.9 0.63 9.3 3.4 1.5 1 0 0 1 1 1 0 PHD-finger BCDHK_Adom3 PF10436.4 KNE01447.1 - 1.1e-26 93.2 2.0 1.8e-26 92.6 1.4 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KNE01447.1 - 2e-12 46.8 0.0 4e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KNE01447.1 - 5.2e-05 22.9 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 KNE01447.1 - 0.00097 18.9 0.0 0.038 13.7 0.0 2.6 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain DUF2013 PF09431.5 KNE01449.1 - 1.7e-38 131.5 4.9 3.9e-38 130.3 3.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Ank_2 PF12796.2 KNE01450.1 - 1.3e-29 102.3 0.3 9.8e-14 51.4 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KNE01450.1 - 7.7e-25 85.4 0.2 0.00019 21.0 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 KNE01450.1 - 2.2e-23 82.1 1.9 3.5e-07 30.5 0.7 4.7 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNE01450.1 - 3.1e-22 76.4 2.4 0.0016 18.4 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat SPX PF03105.14 KNE01450.1 - 2e-20 73.7 22.7 5.3e-19 69.0 11.2 3.0 2 1 0 2 2 2 1 SPX domain Ank_5 PF13857.1 KNE01450.1 - 5.7e-15 54.9 1.5 0.0051 17.0 0.0 5.7 1 1 3 5 5 5 4 Ankyrin repeats (many copies) Ran_BP1 PF00638.13 KNE01451.1 - 6.5e-53 177.9 1.4 6.5e-53 177.9 0.9 1.6 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.18 KNE01451.1 - 1.2e-05 24.9 0.5 0.00019 21.1 0.3 2.2 1 1 0 1 1 1 1 WH1 domain SR-25 PF10500.4 KNE01451.1 - 0.00011 21.7 8.8 0.00016 21.2 6.1 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CDC27 PF09507.5 KNE01451.1 - 0.041 13.1 17.6 0.063 12.4 12.2 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 AIF_C PF14721.1 KNE01451.1 - 0.39 10.9 2.8 0.83 9.9 2.0 1.6 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CLPTM1 PF05602.7 KNE01451.1 - 0.42 9.2 2.4 0.59 8.7 1.7 1.2 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Daxx PF03344.10 KNE01451.1 - 0.6 8.5 12.3 0.67 8.3 8.5 1.1 1 0 0 1 1 1 0 Daxx Family DUF1681 PF07933.9 KNE01451.1 - 2.6 7.5 6.4 0.56 9.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1681) FAM176 PF14851.1 KNE01451.1 - 2.7 7.6 7.3 4.7 6.8 5.0 1.5 1 0 0 1 1 1 0 FAM176 family Ycf1 PF05758.7 KNE01451.1 - 4.3 4.9 9.5 3.9 5.0 6.6 1.1 1 0 0 1 1 1 0 Ycf1 DUF788 PF05620.6 KNE01451.1 - 7.7 6.3 5.6 12 5.7 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) CRM1_C PF08767.6 KNE01452.1 - 2.5e-121 404.4 1.6 2.5e-121 404.4 1.1 2.6 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 KNE01452.1 - 6.3e-37 126.7 6.0 6.3e-37 126.7 4.2 3.6 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 KNE01452.1 - 1.8e-15 56.5 0.3 1.1e-14 54.0 0.2 2.5 1 0 0 1 1 1 1 Importin-beta N-terminal domain V-ATPase_H_C PF11698.3 KNE01452.1 - 0.0041 17.0 3.0 3.9 7.4 0.1 4.0 3 0 0 3 3 3 1 V-ATPase subunit H DUF3385 PF11865.3 KNE01452.1 - 0.088 12.7 0.0 0.088 12.7 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) Ldh_1_N PF00056.18 KNE01453.1 - 5.4e-42 142.9 0.1 8.6e-42 142.2 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KNE01453.1 - 8.3e-38 129.8 0.1 1.2e-37 129.3 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 KNE01453.1 - 0.0023 16.6 0.0 0.0036 16.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NR_Repeat PF14046.1 KNE01454.1 - 0.16 11.7 0.4 0.29 10.8 0.3 1.4 1 0 0 1 1 1 0 Nuclear receptor repeat Glyco_transf_56 PF07429.6 KNE01456.1 - 0.13 11.2 0.0 0.14 11.0 0.0 1.0 1 0 0 1 1 1 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 Trehalase PF01204.13 KNE01457.1 - 3e-175 583.7 1.4 3.6e-175 583.4 1.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 KNE01457.1 - 4.4e-17 61.1 0.7 7.8e-17 60.2 0.5 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain polyprenyl_synt PF00348.12 KNE01458.1 - 1.1e-47 162.1 0.0 6.5e-44 149.7 0.0 3.1 2 1 0 2 2 2 2 Polyprenyl synthetase Ribosomal_L3 PF00297.17 KNE01459.1 - 2.1e-33 115.8 3.0 6.7e-32 110.9 2.1 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 Ribosomal_L6 PF00347.18 KNE01460.1 - 1.3e-20 73.6 0.5 4.1e-09 36.7 0.0 2.4 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_S4 PF00163.14 KNE01461.1 - 1.3e-24 86.4 1.2 1.9e-24 85.8 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KNE01461.1 - 1.8e-08 33.6 0.0 4.9e-08 32.2 0.0 1.7 2 0 0 2 2 2 1 S4 domain BioT2 PF15368.1 KNE01464.1 - 0.022 14.5 0.0 0.029 14.1 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis family BioT2 NAD_binding_6 PF08030.7 KNE01465.1 - 1.6e-22 80.0 0.0 3.4e-22 79.0 0.0 1.6 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KNE01465.1 - 4.4e-20 71.5 0.0 8.9e-20 70.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KNE01465.1 - 1.1e-17 64.2 6.5 1.1e-17 64.2 4.5 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component CAF-1_p150 PF11600.3 KNE01467.1 - 0.47 9.7 11.8 0.69 9.2 8.2 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Acetyltransf_1 PF00583.19 KNE01468.1 - 7.4e-09 35.5 0.0 2.9e-08 33.6 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KNE01468.1 - 1.6e-05 24.9 0.1 3.4e-05 23.9 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KNE01468.1 - 0.00018 21.5 0.1 0.0054 16.8 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KNE01468.1 - 0.0078 15.9 0.0 0.85 9.4 0.0 2.7 2 1 0 2 2 2 1 FR47-like protein Stork_head PF10264.4 KNE01468.1 - 0.08 13.1 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain SNF2_N PF00176.18 KNE01469.1 - 1e-70 237.9 0.0 2.5e-70 236.6 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 KNE01469.1 - 2e-26 92.1 2.6 3e-26 91.5 0.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.19 KNE01469.1 - 6.8e-21 73.7 8.4 1.8e-12 46.7 1.2 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 KNE01469.1 - 4.5e-15 55.2 0.0 1.2e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KNE01469.1 - 0.0011 18.5 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Uma2 PF05685.7 KNE01470.1 - 0.017 14.4 0.0 0.018 14.3 0.0 1.1 1 0 0 1 1 1 0 Putative restriction endonuclease ABC_tran PF00005.22 KNE01471.1 - 2.2e-33 115.4 0.0 6.7e-17 62.0 0.0 2.7 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KNE01471.1 - 3.7e-15 56.6 4.4 0.0041 17.1 0.0 4.2 2 2 2 4 4 4 4 AAA domain RLI PF04068.10 KNE01471.1 - 4.1e-13 48.6 5.7 1.1e-12 47.2 4.0 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.14 KNE01471.1 - 2.6e-11 43.1 2.9 0.0011 18.2 0.0 4.2 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 KNE01471.1 - 5.2e-08 32.1 3.3 5.2e-08 32.1 2.3 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA PF00004.24 KNE01471.1 - 1.2e-06 28.7 0.0 0.0035 17.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KNE01471.1 - 3.8e-06 27.7 0.1 0.017 15.9 0.0 2.8 2 2 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KNE01471.1 - 9.7e-06 25.7 0.0 0.0098 16.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain Fer4_6 PF12837.2 KNE01471.1 - 3.9e-05 23.3 2.8 3.9e-05 23.3 2.0 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_25 PF13481.1 KNE01471.1 - 6.6e-05 22.4 0.1 0.036 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KNE01471.1 - 9.2e-05 22.0 0.3 0.0012 18.5 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_7 PF12838.2 KNE01471.1 - 0.0001 22.6 7.8 0.00057 20.2 0.3 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_15 PF13175.1 KNE01471.1 - 0.00014 21.0 0.1 2.6 7.0 0.0 4.0 4 0 0 4 4 4 1 AAA ATPase domain VirE PF05272.6 KNE01471.1 - 0.00018 21.0 0.0 0.28 10.6 0.0 2.5 2 0 0 2 2 2 2 Virulence-associated protein E RNA_helicase PF00910.17 KNE01471.1 - 0.00021 21.4 0.1 0.055 13.6 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_29 PF13555.1 KNE01471.1 - 0.00022 20.6 0.2 0.22 11.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 KNE01471.1 - 0.00024 20.9 0.1 0.073 12.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KNE01471.1 - 0.00032 21.0 0.3 1.6 9.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 KNE01471.1 - 0.00034 20.3 0.8 0.072 12.7 0.0 2.8 3 0 0 3 3 2 1 NACHT domain DUF258 PF03193.11 KNE01471.1 - 0.00037 19.7 2.0 0.69 9.0 0.0 3.0 3 0 0 3 3 2 2 Protein of unknown function, DUF258 Fer4_2 PF12797.2 KNE01471.1 - 0.00041 20.1 1.8 0.00041 20.1 1.2 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.1 KNE01471.1 - 0.00052 19.8 11.6 0.0012 18.6 8.1 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_16 PF13191.1 KNE01471.1 - 0.00062 19.7 0.0 0.35 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 KNE01471.1 - 0.00095 18.8 0.7 0.25 11.0 0.0 2.8 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_16 PF13484.1 KNE01471.1 - 0.0014 19.3 5.0 0.0037 17.9 0.1 2.5 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain SbcCD_C PF13558.1 KNE01471.1 - 0.002 17.9 0.2 4.9 7.1 0.0 3.7 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 KNE01471.1 - 0.0027 18.0 1.5 0.052 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain Fer4_9 PF13187.1 KNE01471.1 - 0.0028 17.9 2.0 0.0028 17.9 1.4 2.5 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 KNE01471.1 - 0.0034 17.1 1.5 0.0034 17.1 1.1 2.4 1 1 1 2 2 2 1 4Fe-4S dicluster domain SRP54 PF00448.17 KNE01471.1 - 0.0043 16.5 3.0 0.17 11.3 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_3 PF12798.2 KNE01471.1 - 0.0059 17.0 4.2 0.0059 17.0 2.9 2.7 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_24 PF13479.1 KNE01471.1 - 0.0062 16.1 1.0 0.068 12.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.1 KNE01471.1 - 0.0077 14.7 0.4 0.021 13.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KNE01471.1 - 0.011 16.1 0.0 7.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Fer4_15 PF13459.1 KNE01471.1 - 0.027 15.0 1.3 0.12 12.9 0.9 2.2 1 0 0 1 1 1 0 4Fe-4S single cluster domain AAA_28 PF13521.1 KNE01471.1 - 0.03 14.2 0.0 12 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.1 KNE01471.1 - 0.04 13.9 7.8 0.11 12.5 5.3 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_30 PF13604.1 KNE01471.1 - 0.041 13.4 0.2 0.78 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain HflK_N PF12221.3 KNE01471.1 - 0.042 13.5 0.1 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial membrane protein N terminal NB-ARC PF00931.17 KNE01471.1 - 0.063 12.1 0.1 4.1 6.1 0.0 2.5 3 0 0 3 3 3 0 NB-ARC domain AAA_14 PF13173.1 KNE01471.1 - 0.066 13.1 0.0 19 5.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain PEPCK_ATP PF01293.15 KNE01471.1 - 0.076 11.5 0.1 0.11 10.9 0.1 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_5 PF07728.9 KNE01471.1 - 0.084 12.5 1.4 0.78 9.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 KNE01471.1 - 0.11 11.9 1.4 4.5 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain Thymidylate_kin PF02223.12 KNE01471.1 - 0.12 11.7 2.1 5.4 6.3 0.1 3.3 4 0 0 4 4 3 0 Thymidylate kinase Rad17 PF03215.10 KNE01471.1 - 0.13 10.8 0.0 3.2 6.3 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein FtsK_SpoIIIE PF01580.13 KNE01471.1 - 0.17 11.3 0.4 3.2 7.1 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 KNE01471.1 - 0.18 11.4 0.7 5.5 6.6 0.0 2.8 2 0 0 2 2 2 0 NTPase Fer4_4 PF12800.2 KNE01471.1 - 0.25 11.7 13.9 0.051 13.9 1.7 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain HSA PF07529.8 KNE01472.1 - 2.5e-15 56.0 1.3 9e-15 54.2 0.0 2.7 2 0 0 2 2 2 1 HSA Myb_DNA-bind_6 PF13921.1 KNE01472.1 - 1.3e-08 34.7 0.6 1.5e-07 31.3 0.1 2.9 3 0 0 3 3 3 1 Myb-like DNA-binding domain UPF0118 PF01594.11 KNE01473.1 - 0.0038 16.2 2.9 0.0054 15.7 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF20 Claudin_2 PF13903.1 KNE01473.1 - 0.0069 16.0 0.2 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction EAP30 PF04157.11 KNE01473.1 - 0.041 13.0 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family Orbi_NS3 PF01616.11 KNE01473.1 - 0.1 11.5 0.2 0.17 10.8 0.2 1.3 1 0 0 1 1 1 0 Orbivirus NS3 NnrU PF07298.6 KNE01473.1 - 0.27 10.5 2.8 0.44 9.8 1.9 1.2 1 0 0 1 1 1 0 NnrU protein zf-DHHC PF01529.15 KNE01473.1 - 2.6 7.4 4.1 4.8 6.5 2.8 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase Sen15 PF09631.5 KNE01474.1 - 1.2e-25 89.6 0.0 1.3e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 Sen15 protein PsaM PF07465.8 KNE01475.1 - 0.036 13.6 0.2 0.047 13.2 0.2 1.1 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) SUN PF03856.8 KNE01476.1 - 6.3e-63 212.3 6.4 7.2e-63 212.1 4.5 1.0 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF3807 PF12720.2 KNE01479.1 - 1.8 8.7 19.2 2.2 8.3 13.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) GAGA_bind PF06217.7 KNE01479.1 - 3.6 7.4 20.0 4.1 7.2 13.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family FLO_LFY PF01698.11 KNE01479.1 - 3.7 6.3 16.2 4.3 6.0 11.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein SRP-alpha_N PF04086.8 KNE01479.1 - 4.1 6.7 22.6 4.3 6.6 15.7 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RR_TM4-6 PF06459.7 KNE01479.1 - 6.6 6.5 17.2 7.1 6.4 11.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.5 KNE01479.1 - 8.4 6.3 25.9 10 6.1 17.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Rhodanese PF00581.15 KNE01480.1 - 1.3e-19 70.5 0.0 1.5e-19 70.3 0.0 1.0 1 0 0 1 1 1 1 Rhodanese-like domain DUF947 PF06102.7 KNE01481.1 - 3.3e-49 166.9 27.0 3.3e-49 166.9 18.7 2.0 1 1 0 2 2 2 1 Domain of unknown function (DUF947) Alg14 PF08660.6 KNE01482.1 - 3.9e-57 192.9 0.1 3.9e-57 192.9 0.1 1.4 2 0 0 2 2 2 1 Oligosaccharide biosynthesis protein Alg14 like ATP-grasp_2 PF08442.5 KNE01484.1 - 7.4e-44 149.5 0.3 1.2e-43 148.8 0.2 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 KNE01484.1 - 5.3e-25 87.8 0.0 1.6e-24 86.2 0.0 1.9 1 0 0 1 1 1 1 CoA-ligase Proteasome PF00227.21 KNE01485.1 - 1.2e-53 181.2 0.1 1.6e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KNE01485.1 - 1.8e-13 49.5 0.1 3.8e-13 48.4 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Mgr1 PF08602.5 KNE01485.1 - 0.2 10.6 0.9 3.7 6.4 0.4 2.0 2 0 0 2 2 2 0 Mgr1-like, i-AAA protease complex subunit Spc97_Spc98 PF04130.8 KNE01486.1 - 1.1e-79 268.2 16.2 1.4e-79 267.8 11.2 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family ThiF PF00899.16 KNE01487.1 - 2.5e-29 101.8 0.0 4e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.14 KNE01487.1 - 0.00092 18.4 0.0 0.082 12.0 0.0 2.6 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KNE01487.1 - 0.0012 18.9 0.0 0.0043 17.1 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 KNE01487.1 - 0.14 11.6 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NMD3 PF04981.8 KNE01488.1 - 3e-71 239.2 0.2 3e-71 239.2 0.2 1.6 2 0 0 2 2 2 1 NMD3 family VPS11_C PF12451.3 KNE01488.1 - 0.0077 16.0 2.1 0.017 15.0 1.5 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Bromodomain PF00439.20 KNE01489.1 - 5.8e-25 87.0 0.5 1.2e-24 86.0 0.3 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 KNE01489.1 - 6.1e-09 35.9 0.1 1.2e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KNE01489.1 - 3.8e-08 33.2 0.0 6.5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KNE01489.1 - 0.031 14.4 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glucosamine_iso PF01182.15 KNE01490.1 - 6.3e-55 185.9 0.0 7.3e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase BiPBP_C PF06832.7 KNE01490.1 - 0.13 12.1 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family CPDase PF07823.6 KNE01491.1 - 1.2e-51 175.0 0.0 1.8e-51 174.4 0.0 1.3 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein LigT_PEase PF02834.11 KNE01491.1 - 0.0022 17.9 0.3 2.1 8.4 0.0 2.6 3 0 0 3 3 3 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.1 KNE01491.1 - 0.005 16.5 1.0 0.093 12.4 0.7 2.2 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily HORMA PF02301.13 KNE01492.1 - 4.1e-40 137.5 0.0 4.6e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 KNE01492.1 - 0.11 11.8 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 13 Cyclin_N PF00134.18 KNE01493.1 - 1.5e-09 37.4 1.0 2.9e-08 33.3 0.7 2.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain YLP PF02757.12 KNE01493.1 - 0.08 12.6 0.9 0.33 10.7 0.4 2.2 2 0 0 2 2 2 0 YLP motif Porin_3 PF01459.17 KNE01494.1 - 2.8e-65 220.3 6.5 3.2e-65 220.1 4.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin Macro_2 PF14519.1 KNE01495.1 - 7.5e-12 44.9 0.0 1.9e-11 43.5 0.0 1.7 1 1 0 1 1 1 1 Macro-like domain Macro PF01661.16 KNE01495.1 - 0.00032 20.5 0.0 0.0025 17.7 0.0 2.3 3 0 0 3 3 3 1 Macro domain NUDIX PF00293.23 KNE01496.1 - 7.8e-16 57.9 0.0 9.8e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain BOP1NT PF08145.7 KNE01497.1 - 3.9e-103 344.7 6.5 9.1e-103 343.5 4.5 1.7 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 KNE01497.1 - 9e-35 117.3 2.4 6.5e-11 41.6 0.1 7.2 7 1 0 7 7 7 4 WD domain, G-beta repeat Daxx PF03344.10 KNE01497.1 - 0.23 9.8 25.7 0.48 8.8 17.8 1.6 1 0 0 1 1 1 0 Daxx Family Ycf1 PF05758.7 KNE01497.1 - 0.89 7.1 7.4 1.2 6.7 5.1 1.2 1 0 0 1 1 1 0 Ycf1 RRM_1 PF00076.17 KNE01498.1 - 1.4e-15 56.6 0.0 3.3e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNE01498.1 - 3e-10 39.9 0.0 4.7e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNE01498.1 - 1.2e-07 31.4 0.0 1.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Slu7 PF11708.3 KNE01498.1 - 0.016 14.9 8.1 0.027 14.2 5.6 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Acyltransferase PF01553.16 KNE01499.1 - 6.7e-05 22.3 0.0 0.00015 21.2 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase Histone PF00125.19 KNE01500.1 - 1.2e-25 89.4 0.0 1.6e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KNE01500.1 - 1e-05 25.4 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KNE01504.1 - 6.3e-23 80.6 0.4 8.7e-23 80.2 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KNE01504.1 - 1.7e-07 31.2 0.2 3.7e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KNE01504.1 - 0.0014 18.8 0.0 0.0023 18.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 KNE01504.1 - 0.015 13.9 2.1 0.018 13.7 1.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ImcF-related_N PF14331.1 KNE01504.1 - 0.091 11.6 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 ImcF-related N-terminal domain HC2 PF07382.6 KNE01504.1 - 2.6 7.8 17.8 6.6 6.5 12.3 1.8 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 PGAP1 PF07819.8 KNE01505.1 - 6.3e-85 284.3 0.0 9.9e-85 283.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KNE01505.1 - 0.00055 19.7 0.0 0.0013 18.4 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNE01505.1 - 0.0006 19.7 0.0 0.00099 19.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KNE01505.1 - 0.037 13.3 0.1 0.077 12.2 0.1 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) ATP-synt_E PF05680.7 KNE01507.1 - 4.3 7.3 9.5 0.78 9.7 0.4 2.3 2 0 0 2 2 2 0 ATP synthase E chain YebO PF13974.1 KNE01507.1 - 7.8 6.3 7.8 1.6 8.5 1.4 2.2 2 0 0 2 2 2 0 YebO-like protein SUR7 PF06687.7 KNE01508.1 - 1.2e-18 67.4 4.2 1.4e-18 67.2 2.9 1.0 1 0 0 1 1 1 1 SUR7/PalI family DUF973 PF06157.6 KNE01508.1 - 0.1 11.5 2.2 0.13 11.1 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF2524 PF10732.4 KNE01510.1 - 0.051 13.7 0.1 0.053 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) DUF3294 PF07957.6 KNE01511.1 - 7.3e-58 195.6 5.1 8.1e-58 195.4 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) DUF1192 PF06698.6 KNE01511.1 - 0.1 12.4 3.7 2 8.2 0.2 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1192) FtsH_ext PF06480.10 KNE01511.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 FtsH Extracellular SlyX PF04102.7 KNE01511.1 - 0.37 11.1 4.2 3.3 8.1 0.5 2.9 3 0 0 3 3 3 0 SlyX FlxA PF14282.1 KNE01511.1 - 2.5 8.0 7.0 1.1 9.2 0.7 2.7 2 1 1 3 3 3 0 FlxA-like protein Ribosomal_L2_C PF03947.13 KNE01512.1 - 1.1e-07 31.7 2.0 1.4e-07 31.3 1.4 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain RRM_1 PF00076.17 KNE01513.1 - 5.3e-10 38.7 4.9 6.2e-07 28.9 0.2 3.0 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNE01513.1 - 5.4e-09 35.7 0.4 4.4e-05 23.2 0.2 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNE01513.1 - 4.1e-06 26.6 0.1 0.00028 20.7 0.1 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L29e PF01779.12 KNE01514.1 - 6.9e-21 73.8 17.0 9.2e-21 73.4 11.8 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family Ribosomal_L7Ae PF01248.21 KNE01515.1 - 1.2e-22 79.2 0.6 2.1e-22 78.4 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PQ-loop PF04193.9 KNE01516.1 - 1.5e-28 98.0 1.0 2.6e-18 65.2 0.3 3.4 4 0 0 4 4 4 2 PQ loop repeat TRAM_LAG1_CLN8 PF03798.11 KNE01516.1 - 0.011 15.3 2.8 0.53 9.7 0.2 2.2 2 0 0 2 2 2 0 TLC domain DUF3278 PF11683.3 KNE01516.1 - 0.081 12.9 2.4 0.13 12.2 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3278) MtN3_slv PF03083.11 KNE01516.1 - 0.14 12.0 2.9 0.73 9.7 0.1 2.7 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Fungal_trans PF04082.13 KNE01517.1 - 6.6e-07 28.4 4.0 6.6e-07 28.4 2.8 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_2 PF13347.1 KNE01519.1 - 0.21 9.9 0.0 0.3 9.4 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein AAA_13 PF13166.1 KNE01519.1 - 0.29 9.5 14.6 0.03 12.8 4.2 2.0 1 1 0 1 1 1 0 AAA domain Med30 PF11315.3 KNE01519.1 - 0.76 9.8 0.0 0.76 9.8 0.0 2.9 2 2 0 3 3 3 0 Mediator complex subunit 30 DUF4259 PF14078.1 KNE01519.1 - 0.78 10.2 9.7 0.11 13.0 1.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4259) Imm42 PF15601.1 KNE01519.1 - 0.88 8.9 3.9 6 6.2 0.3 2.4 2 0 0 2 2 2 0 Immunity protein 42 Tropomyosin_1 PF12718.2 KNE01519.1 - 8.6 6.2 28.3 0.34 10.7 4.8 3.5 3 1 1 4 4 4 0 Tropomyosin like Nsp1_C PF05064.8 KNE01519.1 - 8.7 6.0 16.5 0.23 11.0 0.8 3.4 3 1 1 4 4 4 0 Nsp1-like C-terminal region DUF2454 PF10521.4 KNE01520.1 - 1.5e-44 152.0 0.1 1.9e-44 151.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) Indigoidine_A PF04227.7 KNE01521.1 - 2.2e-116 388.2 1.0 2.5e-116 388.0 0.7 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein Skp1_POZ PF03931.10 KNE01521.1 - 0.089 12.9 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain PfkB PF00294.19 KNE01522.1 - 1.2e-13 50.9 0.0 6.4e-07 28.8 0.0 2.8 2 1 0 2 2 2 2 pfkB family carbohydrate kinase BAF1_ABF1 PF04684.8 KNE01523.1 - 0.14 11.0 14.5 0.19 10.5 10.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Med15 PF09606.5 KNE01523.1 - 0.89 7.6 16.6 0.99 7.5 11.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2971 PF11185.3 KNE01523.1 - 5.9 7.6 7.9 16 6.2 5.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2971) Chalcone PF02431.10 KNE01524.1 - 1.9e-37 128.6 0.0 2.2e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Chalcone-flavanone isomerase NTP_transferase PF00483.18 KNE01525.1 - 3.2e-50 170.7 0.0 4.5e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 KNE01525.1 - 1.3e-11 44.7 0.0 2.1e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 KNE01525.1 - 5.8e-10 38.2 1.9 1.1e-07 30.9 0.2 3.2 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KNE01525.1 - 0.00017 21.0 4.9 0.041 13.4 0.4 3.1 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 KNE01525.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Cytidylyltransferase MFS_1 PF07690.11 KNE01527.1 - 7.7e-18 64.3 21.6 1.2e-17 63.6 15.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily FBPase PF00316.15 KNE01528.1 - 1.3e-136 454.7 0.0 1.4e-136 454.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 KNE01528.1 - 0.028 13.7 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Inositol monophosphatase family NdhM PF10664.4 KNE01528.1 - 0.031 14.1 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M BTV_NS2 PF04514.7 KNE01530.1 - 3.8 6.3 8.8 4.1 6.1 6.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF2422 PF10337.4 KNE01530.1 - 8 5.1 7.0 4.5 5.9 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2422) CytochromB561_N PF09786.4 KNE01530.1 - 8.8 4.6 13.4 9.9 4.4 9.3 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal SecY PF00344.15 KNE01531.1 - 1.7e-88 296.9 14.3 2.1e-88 296.5 9.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KNE01531.1 - 2.3e-16 58.9 0.1 2.3e-16 58.9 0.1 2.7 3 0 0 3 3 3 1 Plug domain of Sec61p Ninjurin PF04923.7 KNE01531.1 - 8.6 6.1 11.5 9.3 6.0 5.7 2.6 2 1 0 2 2 2 0 Ninjurin AAA PF00004.24 KNE01532.1 - 1.2e-37 129.0 0.0 2.9e-37 127.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KNE01532.1 - 5.8e-07 29.3 0.1 7.6e-05 22.5 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 KNE01532.1 - 5.3e-06 25.6 0.0 1.4e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KNE01532.1 - 5.9e-06 26.4 0.4 0.00048 20.2 0.1 3.1 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.8 KNE01532.1 - 0.00034 19.4 0.0 0.00066 18.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 KNE01532.1 - 0.00062 19.6 0.0 0.0031 17.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KNE01532.1 - 0.00063 19.4 0.0 0.0031 17.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KNE01532.1 - 0.00065 19.7 0.5 0.014 15.4 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 KNE01532.1 - 0.0012 18.7 0.0 0.0033 17.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 KNE01532.1 - 0.0028 17.1 0.0 0.0056 16.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KNE01532.1 - 0.0075 15.4 0.1 0.0075 15.4 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KNE01532.1 - 0.0085 15.9 0.0 0.023 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KNE01532.1 - 0.0095 15.6 0.0 0.032 13.9 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 KNE01532.1 - 0.02 14.3 0.3 0.1 11.9 0.0 2.3 2 1 1 3 3 3 0 AAA domain AAA_24 PF13479.1 KNE01532.1 - 0.029 13.9 0.0 0.091 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KNE01532.1 - 0.037 14.2 1.3 0.58 10.3 0.0 2.9 3 0 0 3 3 2 0 RNA helicase PhoH PF02562.11 KNE01532.1 - 0.058 12.6 0.0 0.22 10.7 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.7 KNE01532.1 - 0.067 12.8 0.1 0.23 11.0 0.0 2.0 2 0 0 2 2 1 0 NACHT domain AAA_17 PF13207.1 KNE01532.1 - 0.071 13.9 2.7 0.09 13.6 0.0 2.6 3 1 0 3 3 2 0 AAA domain KaiC PF06745.8 KNE01532.1 - 0.08 12.0 0.0 1.8 7.6 0.0 2.4 1 1 1 2 2 2 0 KaiC AAA_28 PF13521.1 KNE01532.1 - 0.099 12.6 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain Guanylate_kin PF00625.16 KNE01532.1 - 0.16 11.4 1.5 0.34 10.3 0.0 2.4 3 0 0 3 3 3 0 Guanylate kinase AAA_18 PF13238.1 KNE01532.1 - 0.4 10.9 3.6 0.54 10.5 0.0 3.0 4 0 0 4 4 3 0 AAA domain Apq12 PF12716.2 KNE01537.1 - 5.4e-07 29.1 12.2 1.1e-06 28.2 8.5 1.5 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis DUF161 PF02588.10 KNE01537.1 - 0.059 13.6 9.7 0.088 13.1 6.7 1.3 1 0 0 1 1 1 0 Uncharacterized BCR, YitT family COG1284 DUF3754 PF12576.3 KNE01537.1 - 1.3 8.6 6.0 2.3 7.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) MFS_1 PF07690.11 KNE01538.1 - 5.8e-40 137.0 39.8 3e-37 128.1 29.5 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KNE01538.1 - 1.3e-17 63.2 26.2 3.4e-17 61.8 18.1 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KNE01538.1 - 1.3e-11 43.8 6.0 1.3e-11 43.8 4.1 3.7 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 KNE01538.1 - 5.8e-05 21.6 2.6 5.8e-05 21.6 1.8 2.9 1 1 1 2 2 2 2 MFS/sugar transport protein DUF4245 PF14030.1 KNE01538.1 - 0.16 11.7 0.3 15 5.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4245) DnaJ-X PF14308.1 KNE01539.1 - 2.6e-60 203.1 16.3 2.6e-60 203.1 11.3 1.9 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 KNE01539.1 - 3.5e-24 84.3 0.4 1.6e-23 82.1 0.3 2.3 1 0 0 1 1 1 1 DnaJ domain Homeobox PF00046.24 KNE01539.1 - 0.072 12.7 2.1 0.32 10.6 1.5 2.2 1 0 0 1 1 1 0 Homeobox domain DUF1045 PF06299.7 KNE01539.1 - 0.15 11.7 4.1 2.1 8.0 0.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1045) BNIP2 PF12496.3 KNE01539.1 - 0.75 9.9 5.7 0.26 11.4 0.5 2.4 2 1 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Complex1_LYR_1 PF13232.1 KNE01540.1 - 1e-17 64.0 1.3 1.3e-17 63.7 0.9 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KNE01540.1 - 9.5e-16 57.3 0.7 1.2e-15 57.0 0.5 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 KNE01540.1 - 0.00047 20.5 1.5 0.0006 20.2 1.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like FMO-like PF00743.14 KNE01541.1 - 4.7e-29 100.9 0.0 4.5e-10 38.3 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KNE01541.1 - 5.6e-13 49.4 1.1 2.3e-10 40.8 0.4 3.0 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KNE01541.1 - 4.3e-11 42.8 0.5 1.1e-08 35.0 0.1 3.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KNE01541.1 - 1.2e-08 34.3 0.3 0.042 12.7 0.0 4.0 1 1 2 4 4 4 3 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KNE01541.1 - 1.8e-07 31.2 0.0 4.3e-06 26.7 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KNE01541.1 - 6.4e-05 22.9 0.1 0.00015 21.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KNE01541.1 - 0.0044 15.9 0.0 0.19 10.6 0.0 2.8 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KNE01541.1 - 0.0057 17.0 1.1 4.1 7.8 0.0 3.1 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KNE01541.1 - 0.046 12.8 0.8 1.7 7.6 0.1 2.9 3 0 0 3 3 3 0 Thi4 family Shikimate_DH PF01488.15 KNE01541.1 - 0.08 13.0 0.0 3.2 7.8 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 KNE01541.1 - 0.17 11.5 0.0 6.7 6.4 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MFS_1 PF07690.11 KNE01542.1 - 7e-46 156.5 18.9 7e-46 156.5 13.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KNE01542.1 - 2.9e-10 39.3 8.1 4.8e-09 35.3 0.2 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter PUCC PF03209.10 KNE01542.1 - 1.9e-05 23.5 1.1 5.8e-05 21.9 0.7 1.9 1 0 0 1 1 1 1 PUCC protein MFS_3 PF05977.8 KNE01542.1 - 0.0099 14.0 7.9 0.022 12.9 5.5 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector Pho86 PF11124.3 KNE01544.1 - 7.4e-66 222.2 0.5 8.4e-66 222.0 0.3 1.0 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 Acetyltransf_1 PF00583.19 KNE01544.1 - 0.096 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Lectin_leg-like PF03388.8 KNE01545.1 - 8.7e-54 182.0 0.0 1.2e-53 181.6 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 KNE01545.1 - 0.034 13.5 0.0 0.073 12.4 0.0 1.5 2 0 0 2 2 2 0 Legume lectin domain FeoB_C PF07664.7 KNE01545.1 - 0.049 13.0 0.1 0.14 11.5 0.1 1.8 1 0 0 1 1 1 0 Ferrous iron transport protein B C terminus HJURP_C PF12347.3 KNE01545.1 - 0.094 12.3 1.7 0.68 9.5 0.0 3.0 3 0 0 3 3 3 0 Holliday junction regulator protein family C-terminal repeat FtsL PF04999.8 KNE01545.1 - 2.3 8.0 7.2 0.12 12.0 0.3 2.3 3 0 0 3 3 3 0 Cell division protein FtsL APC2 PF08672.6 KNE01546.1 - 0.0024 18.0 0.2 0.0059 16.8 0.1 1.8 1 1 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 PBP_dimer PF03717.10 KNE01546.1 - 0.16 12.0 1.2 0.21 11.6 0.4 1.5 1 1 1 2 2 2 0 Penicillin-binding Protein dimerisation domain His_Phos_1 PF00300.17 KNE01547.1 - 7.5e-29 100.8 0.4 8.9e-29 100.6 0.3 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 KNE01547.1 - 2.2e-05 23.9 0.0 2.7e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Sigma70_r4 PF04545.11 KNE01547.1 - 0.012 14.9 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 DUF3352 PF11832.3 KNE01547.1 - 0.018 13.4 0.0 0.022 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3352) IU_nuc_hydro PF01156.14 KNE01550.1 - 1.1e-79 267.8 0.0 1.3e-79 267.6 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF1858 PF08984.6 KNE01550.1 - 0.043 13.4 0.0 8.7 6.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1858) Abhydro_lipase PF04083.11 KNE01551.1 - 1.6e-18 65.7 0.0 3.1e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 KNE01551.1 - 2e-05 24.6 0.0 8.1e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNE01551.1 - 0.00044 20.0 0.0 0.00078 19.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Uds1 PF15456.1 KNE01551.1 - 0.13 12.2 4.0 0.26 11.2 2.8 1.4 1 0 0 1 1 1 0 Up-regulated During Septation Striatin PF08232.7 KNE01551.1 - 0.14 12.4 6.4 0.24 11.7 4.4 1.4 1 0 0 1 1 1 0 Striatin family Tropomyosin_1 PF12718.2 KNE01551.1 - 7.1 6.4 13.3 0.25 11.1 2.5 2.1 1 1 1 2 2 2 0 Tropomyosin like 2-Hacid_dh_C PF02826.14 KNE01555.1 - 8.3e-54 181.4 0.0 9.9e-53 177.9 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KNE01555.1 - 3.1e-10 39.6 0.0 5.3e-10 38.8 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KNE01555.1 - 0.0022 17.8 0.0 0.0053 16.6 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 KNE01555.1 - 0.026 14.6 0.0 0.074 13.1 0.0 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 KNE01555.1 - 0.062 13.7 0.0 0.17 12.3 0.0 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 KNE01555.1 - 0.12 12.9 0.9 0.97 9.9 0.4 2.6 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Peptidase_M28 PF04389.12 KNE01556.1 - 1.5e-34 119.2 0.0 2.8e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KNE01556.1 - 3.4e-17 61.9 0.1 9.2e-17 60.5 0.0 1.8 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 KNE01556.1 - 0.00096 18.7 0.1 0.0047 16.4 0.0 1.7 1 1 1 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 KNE01556.1 - 0.0034 16.1 0.0 0.0053 15.5 0.0 1.3 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase DnaJ PF00226.26 KNE01557.1 - 2.4e-22 78.4 3.4 2.4e-22 78.4 2.3 2.1 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.23 KNE01557.1 - 2.1e-05 23.9 0.0 0.00072 19.0 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KNE01557.1 - 0.00077 19.0 0.1 0.011 15.4 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KNE01557.1 - 0.00086 19.1 0.0 0.0049 16.6 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KNE01557.1 - 0.0016 18.0 1.2 0.0044 16.6 0.0 2.5 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 KNE01557.1 - 0.0041 16.9 0.0 0.11 12.4 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KNE01557.1 - 0.056 13.9 1.9 0.72 10.4 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3987 PF13148.1 KNE01557.1 - 0.24 9.9 9.9 0.81 8.1 5.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Kei1 PF08552.6 KNE01557.1 - 1.8 8.1 9.0 43 3.7 0.0 2.2 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 AAA PF00004.24 KNE01558.1 - 2.5e-43 147.4 0.0 4.6e-43 146.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KNE01558.1 - 1.4e-07 31.2 0.0 4.2e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KNE01558.1 - 7.2e-07 29.2 0.0 1.5e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KNE01558.1 - 2.8e-06 27.4 0.1 0.00016 21.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KNE01558.1 - 1.6e-05 25.0 0.0 5e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KNE01558.1 - 0.00019 22.2 0.1 0.00067 20.4 0.0 2.0 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KNE01558.1 - 0.00034 19.7 0.0 0.00057 19.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KNE01558.1 - 0.00041 19.8 0.0 0.00076 18.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 KNE01558.1 - 0.00088 18.9 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KNE01558.1 - 0.0012 18.7 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KNE01558.1 - 0.0015 18.4 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KNE01558.1 - 0.003 16.6 0.0 0.0092 15.0 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.1 KNE01558.1 - 0.0062 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KNE01558.1 - 0.0076 16.5 0.3 0.042 14.1 0.0 2.4 3 1 0 3 3 3 1 AAA domain AAA_24 PF13479.1 KNE01558.1 - 0.0099 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KNE01558.1 - 0.01 15.4 0.0 0.026 14.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 KNE01558.1 - 0.013 14.2 0.0 0.027 13.1 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus Tropomyosin PF00261.15 KNE01558.1 - 0.013 14.5 2.7 0.016 14.3 0.7 1.9 2 0 0 2 2 2 0 Tropomyosin AAA_25 PF13481.1 KNE01558.1 - 0.022 14.1 0.0 0.11 11.8 0.0 2.0 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KNE01558.1 - 0.022 13.8 0.0 0.049 12.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KNE01558.1 - 0.024 14.8 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.11 KNE01558.1 - 0.024 13.8 0.0 0.084 12.0 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_13 PF13166.1 KNE01558.1 - 0.031 12.7 0.2 0.62 8.4 0.2 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KNE01558.1 - 0.037 12.8 0.0 0.095 11.5 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain DivIC PF04977.10 KNE01558.1 - 0.037 13.5 2.1 0.09 12.2 1.5 1.6 1 0 0 1 1 1 0 Septum formation initiator CTC1_2 PF15491.1 KNE01558.1 - 0.038 12.9 0.1 0.066 12.2 0.1 1.3 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 NACHT PF05729.7 KNE01558.1 - 0.042 13.5 0.0 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 NACHT domain KaiC PF06745.8 KNE01558.1 - 0.053 12.6 0.0 0.14 11.2 0.0 1.7 1 0 0 1 1 1 0 KaiC Cluap1 PF10234.4 KNE01558.1 - 0.055 12.6 1.0 0.093 11.9 0.7 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 Laminin_II PF06009.7 KNE01558.1 - 0.072 12.8 1.0 2 8.1 0.1 2.7 3 0 0 3 3 3 0 Laminin Domain II Sigma54_activat PF00158.21 KNE01558.1 - 0.082 12.3 0.1 0.48 9.8 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain Spc24 PF08286.6 KNE01558.1 - 0.12 12.1 0.9 0.31 10.7 0.6 1.7 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF2075 PF09848.4 KNE01558.1 - 0.12 11.3 0.5 0.5 9.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF2072 PF09845.4 KNE01558.1 - 0.14 12.0 0.5 0.31 10.9 0.3 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) ATG16 PF08614.6 KNE01558.1 - 0.17 11.7 5.1 0.3 10.8 3.5 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Adeno_100 PF02438.11 KNE01560.1 - 0.12 10.5 1.8 0.14 10.3 1.3 1.0 1 0 0 1 1 1 0 Late 100kD protein DUF1068 PF06364.7 KNE01560.1 - 3.5 7.1 6.5 0.83 9.2 2.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1068) DIM PF08194.7 KNE01560.1 - 9.7 6.2 9.5 4.9 7.1 1.7 2.5 2 0 0 2 2 2 0 DIM protein Glyco_hydr_30_2 PF14587.1 KNE01561.1 - 0.13 11.1 0.0 0.14 11.1 0.0 1.0 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 MIF4G PF02854.14 KNE01562.1 - 1.7e-43 148.5 0.4 2.6e-43 147.8 0.3 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 KNE01562.1 - 5.3e-17 61.4 0.1 1.9e-16 59.7 0.1 2.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 DUF3955 PF13127.1 KNE01563.1 - 0.28 10.7 4.1 3.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3955) AAA PF00004.24 KNE01564.1 - 3.8e-17 62.7 1.1 3e-16 59.7 0.0 2.5 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KNE01564.1 - 3.3e-09 36.1 0.0 9e-09 34.7 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KNE01564.1 - 1.8e-08 35.2 0.1 2.3e-07 31.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KNE01564.1 - 5.5e-08 32.7 0.2 1.6e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KNE01564.1 - 9.7e-08 31.8 0.0 2.4e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KNE01564.1 - 5.9e-07 29.6 1.5 3.9e-06 27.0 0.1 2.9 2 2 1 3 3 2 1 AAA domain AAA_18 PF13238.1 KNE01564.1 - 2.2e-06 27.9 0.1 7.9e-06 26.2 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_2 PF07724.9 KNE01564.1 - 4.4e-06 26.7 0.0 3.6e-05 23.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.1 KNE01564.1 - 3e-05 23.7 0.0 5.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 KNE01564.1 - 4.7e-05 22.9 0.0 0.0052 16.2 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_10 PF12846.2 KNE01564.1 - 0.00025 20.5 2.1 0.36 10.2 0.0 3.4 3 0 0 3 3 3 1 AAA-like domain AAA_28 PF13521.1 KNE01564.1 - 0.0004 20.3 0.0 0.001 19.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta2 PF13177.1 KNE01564.1 - 0.00051 19.7 0.8 0.0099 15.5 0.0 2.7 2 2 0 3 3 3 1 DNA polymerase III, delta subunit AAA_33 PF13671.1 KNE01564.1 - 0.00054 19.8 0.2 0.0018 18.1 0.0 2.1 2 1 0 2 2 1 1 AAA domain NACHT PF05729.7 KNE01564.1 - 0.00098 18.8 0.6 0.035 13.7 0.5 2.6 2 1 0 2 2 1 1 NACHT domain AAA_3 PF07726.6 KNE01564.1 - 0.0013 18.3 0.0 0.0028 17.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KNE01564.1 - 0.0037 17.2 2.4 0.06 13.3 0.0 2.8 2 1 0 3 3 2 1 AAA ATPase domain Mg_chelatase PF01078.16 KNE01564.1 - 0.005 16.0 0.0 0.22 10.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KNE01564.1 - 0.0068 16.5 0.0 0.021 14.9 0.0 1.9 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.12 KNE01564.1 - 0.011 15.1 0.0 0.029 13.8 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 KNE01564.1 - 0.027 14.2 0.0 0.066 12.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain NTPase_1 PF03266.10 KNE01564.1 - 0.036 13.7 0.1 0.36 10.5 0.0 2.4 2 0 0 2 2 2 0 NTPase ResIII PF04851.10 KNE01564.1 - 0.044 13.6 0.3 0.17 11.6 0.0 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit SseB_C PF14581.1 KNE01564.1 - 0.063 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 SseB protein C-terminal domain AAA_25 PF13481.1 KNE01564.1 - 0.068 12.5 0.6 0.27 10.5 0.1 2.1 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KNE01564.1 - 0.084 13.1 0.0 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Sigma54_activ_2 PF14532.1 KNE01564.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain LIM_bind PF01803.11 KNE01566.1 - 3.9e-41 140.7 0.0 3.9e-41 140.7 0.0 3.6 3 1 1 4 4 4 1 LIM-domain binding protein DUF1729 PF08354.5 KNE01567.1 - 0.12 12.1 0.2 0.18 11.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) PAPA-1 PF04795.7 KNE01568.1 - 1.3e-13 51.4 5.4 1.3e-13 51.4 3.7 3.2 2 1 2 4 4 4 1 PAPA-1-like conserved region Neugrin PF06413.6 KNE01571.1 - 8.1e-07 29.0 6.2 1.2e-06 28.5 3.9 1.6 1 1 0 1 1 1 1 Neugrin VID27 PF08553.5 KNE01572.1 - 1.3e-57 195.6 0.6 1.5e-57 195.4 0.5 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein DUF2697 PF10906.3 KNE01573.1 - 1e-27 95.8 0.4 1.2e-27 95.7 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2697) Ost4 PF10215.4 KNE01574.1 - 2.8e-10 39.5 0.3 3.8e-10 39.0 0.2 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase RGS PF00615.14 KNE01577.1 - 8.3e-07 29.1 0.0 1.4e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain bZIP_2 PF07716.10 KNE01578.1 - 7.5e-10 38.4 8.1 1.9e-09 37.1 5.6 1.8 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KNE01578.1 - 0.0028 17.5 11.4 0.008 16.1 7.0 2.4 1 1 0 1 1 1 1 bZIP transcription factor DUF2396 PF09654.5 KNE01579.1 - 0.044 13.7 0.0 0.046 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2396) CPSase_L_D2 PF02786.12 KNE01583.1 - 2.1e-80 268.9 0.1 3.8e-80 268.1 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 KNE01583.1 - 6.9e-65 218.1 0.0 1.4e-64 217.1 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 KNE01583.1 - 2.4e-35 120.9 0.0 5.9e-35 119.6 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KNE01583.1 - 2.6e-31 107.7 0.0 6.4e-31 106.5 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 KNE01583.1 - 2.2e-29 102.7 0.1 4.8e-29 101.6 0.1 1.5 1 0 0 1 1 1 1 HMGL-like ATPgrasp_Ter PF15632.1 KNE01583.1 - 3.1e-18 65.6 0.0 2.1e-17 62.9 0.0 2.1 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 KNE01583.1 - 1.8e-16 59.5 6.1 1.8e-16 59.5 4.3 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KNE01583.1 - 6.3e-15 55.3 0.1 1.3e-14 54.3 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KNE01583.1 - 1e-08 34.8 0.0 3.2e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 KNE01583.1 - 5.4e-08 32.3 5.1 0.00018 21.0 0.2 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 KNE01583.1 - 9.2e-07 28.3 0.0 1.9e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KNE01583.1 - 9.3e-07 28.5 0.0 7.5e-06 25.5 0.0 2.3 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KNE01583.1 - 1.5e-05 24.8 0.0 3.5e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.1 KNE01583.1 - 0.00032 20.3 0.9 0.0014 18.2 0.7 2.1 2 0 0 2 2 1 1 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.1 KNE01583.1 - 0.00044 20.5 1.0 0.33 11.2 0.1 2.9 2 0 0 2 2 2 1 HlyD family secretion protein NQRA PF05896.6 KNE01583.1 - 0.0037 16.4 0.5 0.007 15.5 0.3 1.4 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GCV_H PF01597.14 KNE01583.1 - 0.004 16.8 0.9 0.018 14.7 0.6 2.1 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD PF00529.15 KNE01583.1 - 0.012 14.9 2.4 0.48 9.6 0.1 2.7 3 0 0 3 3 3 0 HlyD family secretion protein HlyD_2 PF12700.2 KNE01583.1 - 0.057 12.5 1.2 4.1 6.4 0.1 2.3 1 1 1 2 2 2 0 HlyD family secretion protein DASH_Duo1 PF08651.5 KNE01584.1 - 9.4e-20 69.9 3.5 1.3e-19 69.4 0.5 1.9 2 0 0 2 2 2 1 DASH complex subunit Duo1 DivIC PF04977.10 KNE01584.1 - 7.8e-05 22.0 9.0 0.0044 16.4 2.3 2.2 2 0 0 2 2 2 2 Septum formation initiator DUF4200 PF13863.1 KNE01584.1 - 0.0011 18.8 4.9 0.0067 16.3 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.7 KNE01584.1 - 0.0022 17.7 7.3 0.0035 17.0 5.1 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein HALZ PF02183.13 KNE01584.1 - 0.003 17.2 0.9 0.003 17.2 0.6 2.2 2 0 0 2 2 2 1 Homeobox associated leucine zipper DivIVA PF05103.8 KNE01584.1 - 0.0036 17.3 5.2 0.025 14.6 0.6 2.1 2 0 0 2 2 2 1 DivIVA protein TMF_DNA_bd PF12329.3 KNE01584.1 - 0.0053 16.5 10.7 0.24 11.2 0.9 2.3 2 0 0 2 2 2 2 TATA element modulatory factor 1 DNA binding UPF0184 PF03670.8 KNE01584.1 - 0.0062 16.6 0.7 0.011 15.9 0.3 1.6 2 0 0 2 2 1 1 Uncharacterised protein family (UPF0184) Uds1 PF15456.1 KNE01584.1 - 0.01 15.8 3.1 0.018 15.0 2.0 1.5 1 1 0 1 1 1 0 Up-regulated During Septation PspA_IM30 PF04012.7 KNE01584.1 - 0.015 14.6 4.1 0.058 12.7 2.8 1.8 1 1 0 1 1 1 0 PspA/IM30 family NPV_P10 PF05531.7 KNE01584.1 - 0.015 15.5 5.0 1.2 9.4 0.3 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Med9 PF07544.8 KNE01584.1 - 0.015 14.9 2.6 0.053 13.2 0.2 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF3450 PF11932.3 KNE01584.1 - 0.016 14.5 5.5 0.32 10.2 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) NYD-SP28_assoc PF14775.1 KNE01584.1 - 0.028 14.1 1.7 0.063 12.9 1.2 1.6 1 0 0 1 1 1 0 Sperm tail C-terminal domain SlyX PF04102.7 KNE01584.1 - 0.029 14.7 5.2 5.5 7.4 0.1 3.0 2 1 1 3 3 3 0 SlyX DASH_Dad2 PF08654.5 KNE01584.1 - 0.03 14.2 6.7 0.033 14.1 1.0 2.1 1 1 1 2 2 2 0 DASH complex subunit Dad2 AAA_13 PF13166.1 KNE01584.1 - 0.058 11.8 3.9 0.067 11.6 2.7 1.0 1 0 0 1 1 1 0 AAA domain Seryl_tRNA_N PF02403.17 KNE01584.1 - 0.062 13.3 7.9 0.3 11.1 1.4 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3585 PF12130.3 KNE01584.1 - 0.086 12.6 4.9 0.59 9.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3585) Mto2_bdg PF12808.2 KNE01584.1 - 0.1 12.7 0.8 0.1 12.7 0.6 2.0 2 0 0 2 2 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Flagellar_rod PF05149.7 KNE01584.1 - 0.1 11.7 4.5 0.33 10.0 0.6 2.0 1 1 1 2 2 2 0 Paraflagellar rod protein bZIP_1 PF00170.16 KNE01584.1 - 0.11 12.4 0.5 0.11 12.4 0.4 2.9 3 0 0 3 3 3 0 bZIP transcription factor CDO_I PF05995.7 KNE01584.1 - 0.12 11.5 0.3 0.2 10.8 0.2 1.4 1 0 0 1 1 1 0 Cysteine dioxygenase type I RasGAP_C PF03836.10 KNE01584.1 - 0.14 11.8 3.1 0.37 10.4 0.4 2.1 2 0 0 2 2 2 0 RasGAP C-terminus APG6 PF04111.7 KNE01584.1 - 0.19 10.7 4.8 0.35 9.8 3.3 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF1192 PF06698.6 KNE01584.1 - 0.24 11.2 1.8 16 5.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) CENP-Q PF13094.1 KNE01584.1 - 0.26 11.2 9.4 1.1 9.3 0.2 2.1 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2951 PF11166.3 KNE01584.1 - 0.27 11.1 4.5 0.13 12.1 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) DUF2968 PF11180.3 KNE01584.1 - 0.3 10.4 4.5 0.11 11.8 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) GAS PF13851.1 KNE01584.1 - 0.32 10.1 9.3 0.095 11.8 1.9 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.15 KNE01584.1 - 0.35 10.6 6.8 0.69 9.6 0.7 2.2 2 0 0 2 2 2 0 Prefoldin subunit ADIP PF11559.3 KNE01584.1 - 0.49 10.2 9.2 1.7 8.5 2.1 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.1 KNE01584.1 - 0.51 9.2 6.6 1.2 8.0 4.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3373 PF11853.3 KNE01584.1 - 0.54 8.7 6.6 0.46 8.9 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3373) DUF1664 PF07889.7 KNE01584.1 - 0.61 9.8 3.7 2.2 8.0 2.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Ax_dynein_light PF10211.4 KNE01584.1 - 0.64 9.8 7.3 0.48 10.2 1.7 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain DUF3381 PF11861.3 KNE01584.1 - 0.66 9.4 6.4 1.3 8.5 4.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3381) DUF4140 PF13600.1 KNE01584.1 - 0.8 10.1 5.3 0.8 10.1 1.2 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Mnd1 PF03962.10 KNE01584.1 - 0.82 9.3 8.1 5.8 6.5 5.6 1.9 1 1 0 1 1 1 0 Mnd1 family FlxA PF14282.1 KNE01584.1 - 0.86 9.5 10.3 3.5 7.6 1.6 2.2 2 0 0 2 2 2 0 FlxA-like protein IncA PF04156.9 KNE01584.1 - 0.91 9.0 9.5 0.32 10.5 3.0 2.0 1 1 0 2 2 2 0 IncA protein DUF972 PF06156.8 KNE01584.1 - 1 9.7 5.9 1.4 9.2 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 KNE01584.1 - 1.2 6.9 3.9 1.4 6.7 2.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GrpE PF01025.14 KNE01584.1 - 1.8 8.0 7.9 0.89 9.0 1.9 2.0 1 1 1 2 2 2 0 GrpE Viral_P18 PF04521.8 KNE01584.1 - 2.7 7.4 7.1 2.2 7.7 0.7 2.1 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Prefoldin PF02996.12 KNE01584.1 - 3 7.4 7.1 9.8 5.8 0.9 2.5 2 1 0 2 2 2 0 Prefoldin subunit Phage_GP20 PF06810.6 KNE01584.1 - 4.8 6.5 10.0 2.2 7.7 2.2 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF16 PF01519.11 KNE01584.1 - 5.6 7.2 6.8 1.7e+02 2.5 4.7 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 Cluap1 PF10234.4 KNE01584.1 - 6.7 5.8 9.4 1.4 8.0 1.8 2.0 2 0 0 2 2 2 0 Clusterin-associated protein-1 Atg14 PF10186.4 KNE01584.1 - 6.8 5.5 8.4 21 3.9 5.9 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Med31 PF05669.7 KNE01585.1 - 6.2e-41 138.3 1.9 7.8e-41 137.9 1.3 1.1 1 0 0 1 1 1 1 SOH1 YafO_toxin PF13957.1 KNE01585.1 - 0.09 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Toxin YafO, type II toxin-antitoxin system Scs3p PF10261.4 KNE01586.1 - 3.5e-69 232.4 16.0 4.4e-69 232.1 11.1 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM He_PIG PF05345.7 KNE01587.1 - 2.1e-14 53.2 12.9 1.1e-06 28.5 0.7 4.1 4 0 0 4 4 4 3 Putative Ig domain DUF4448 PF14610.1 KNE01587.1 - 3.5e-06 26.6 0.0 7.7e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Sarcoglycan_2 PF05510.8 KNE01587.1 - 8.5e-05 21.0 0.1 0.058 11.6 0.0 3.5 3 1 1 4 4 4 2 Sarcoglycan alpha/epsilon TMEM154 PF15102.1 KNE01587.1 - 0.00019 21.1 0.0 0.00057 19.6 0.0 1.8 1 0 0 1 1 1 1 TMEM154 protein family SKG6 PF08693.5 KNE01587.1 - 0.0028 16.9 0.0 0.0085 15.3 0.0 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.7 KNE01587.1 - 0.0035 16.7 0.0 0.014 14.7 0.0 2.1 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Herpes_gE PF02480.11 KNE01587.1 - 0.068 11.4 0.0 0.1 10.8 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.10 KNE01587.1 - 0.12 11.9 0.2 0.24 10.9 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Tweety PF04906.8 KNE01587.1 - 0.23 9.8 0.1 0.35 9.2 0.0 1.2 1 0 0 1 1 1 0 Tweety 4HBT PF03061.17 KNE01588.1 - 2.8e-05 24.1 0.9 0.27 11.3 0.0 2.8 2 1 0 2 2 2 2 Thioesterase superfamily Transket_pyr PF02779.19 KNE01589.1 - 4.1e-45 153.4 0.0 6.2e-45 152.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KNE01589.1 - 4.6e-36 123.4 0.0 8.1e-36 122.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Acatn PF13000.2 KNE01591.1 - 2.8e-164 547.6 16.3 8.2e-112 374.4 4.6 2.1 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 ubiquitin PF00240.18 KNE01592.1 - 6.1e-06 25.5 0.6 7.7e-06 25.2 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 KNE01592.1 - 0.0039 17.4 0.5 0.018 15.3 0.3 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 KNE01592.1 - 0.039 13.6 0.2 0.045 13.4 0.1 1.1 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Metallophos PF00149.23 KNE01593.1 - 1.3e-40 138.9 0.9 1.8e-40 138.5 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Aminotran_3 PF00202.16 KNE01594.1 - 2.4e-104 348.8 0.0 2.9e-104 348.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III IceA2 PF05862.6 KNE01594.1 - 0.094 12.4 0.2 14 5.5 0.0 2.7 2 0 0 2 2 2 0 Helicobacter pylori IceA2 protein Cation_efflux PF01545.16 KNE01595.1 - 1.2e-17 63.9 8.4 1.6e-17 63.5 5.8 1.1 1 0 0 1 1 1 1 Cation efflux family Med12 PF09497.5 KNE01596.1 - 4.5e-25 87.4 0.9 1.3e-24 85.9 0.2 2.1 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Myosin_head PF00063.16 KNE01597.1 - 1.6e-219 730.5 8.4 2.2e-219 730.0 5.8 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KNE01597.1 - 1.2e-42 145.5 0.0 2.6e-42 144.3 0.0 1.7 1 0 0 1 1 1 1 Myosin tail Hpr_kinase_C PF07475.7 KNE01597.1 - 0.00013 21.3 0.7 0.26 10.5 0.1 2.5 2 0 0 2 2 2 2 HPr Serine kinase C-terminal domain AAA_22 PF13401.1 KNE01597.1 - 0.0055 16.8 0.0 0.02 15.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KNE01597.1 - 0.0082 16.9 0.1 0.048 14.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain SH3_1 PF00018.23 KNE01597.1 - 0.037 13.4 0.0 0.081 12.3 0.0 1.6 1 0 0 1 1 1 0 SH3 domain AAA_16 PF13191.1 KNE01597.1 - 0.06 13.3 0.0 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain UPF0079 PF02367.12 KNE01597.1 - 0.091 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KNE01597.1 - 0.11 12.1 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain IQ PF00612.22 KNE01597.1 - 0.49 10.1 12.5 1.4 8.7 2.7 2.6 1 1 1 2 2 2 0 IQ calmodulin-binding motif WD40 PF00400.27 KNE01598.1 - 8.9e-85 275.8 31.0 2.1e-12 46.4 0.1 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 KNE01598.1 - 2e-08 34.1 0.0 3.9e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 KNE01598.1 - 1e-06 27.2 10.5 0.02 13.0 0.1 4.7 3 3 2 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.6 KNE01598.1 - 3.7e-05 23.5 0.8 0.0082 15.8 0.0 3.5 2 2 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KNE01598.1 - 0.0079 14.9 0.6 0.13 10.9 0.2 2.5 2 1 0 2 2 2 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 KNE01598.1 - 0.015 13.6 0.1 0.091 11.0 0.1 2.1 1 1 1 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.7 KNE01598.1 - 0.089 12.4 1.2 2.1 8.0 0.1 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.1 KNE01598.1 - 0.11 12.2 0.0 11 5.8 0.0 3.8 4 2 1 5 5 5 0 Ciliary BBSome complex subunit 2, middle region LRR_4 PF12799.2 KNE01599.1 - 6e-06 25.7 2.9 6e-06 25.7 2.0 5.1 2 1 5 7 7 7 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KNE01599.1 - 0.00028 20.5 4.8 0.00028 20.5 3.3 4.3 1 1 3 4 4 4 2 Leucine rich repeat F-box PF00646.28 KNE01599.1 - 0.035 13.7 2.0 0.072 12.7 0.2 2.6 2 0 0 2 2 2 0 F-box domain LRR_7 PF13504.1 KNE01599.1 - 0.07 13.3 18.7 2.7 8.5 0.2 6.9 9 1 0 9 9 9 0 Leucine rich repeat LRR_6 PF13516.1 KNE01599.1 - 1 9.6 17.4 16 5.9 0.2 6.0 4 2 2 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.28 KNE01599.1 - 5.3 7.4 25.3 0.36 11.0 0.2 6.0 7 3 1 8 8 8 0 Leucine Rich Repeat Pkinase PF00069.20 KNE01601.1 - 8.6e-70 234.8 0.1 3.4e-68 229.6 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE01601.1 - 6e-38 130.3 0.1 4.8e-37 127.4 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KNE01601.1 - 2.8e-09 36.3 0.0 9.1e-09 34.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KNE01601.1 - 0.002 17.9 0.0 0.0046 16.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Img2 PF05046.9 KNE01603.1 - 3e-20 72.2 0.2 4.1e-20 71.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Ependymin PF00811.13 KNE01603.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.4 1 1 0 1 1 1 0 Ependymin LSM PF01423.17 KNE01603.1 - 0.1 12.1 0.3 0.17 11.4 0.2 1.3 1 0 0 1 1 1 0 LSM domain zf-H2C2_2 PF13465.1 KNE01604.1 - 1.1e-20 72.8 47.5 3.9e-08 33.1 2.7 9.2 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2 PF00096.21 KNE01604.1 - 2.2e-17 62.2 50.6 5.2e-05 23.3 1.1 8.5 8 0 0 8 8 8 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNE01604.1 - 3.9e-07 29.9 55.0 0.015 15.5 0.4 8.7 8 1 0 8 8 8 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KNE01604.1 - 2.9e-05 24.0 21.6 0.01 15.9 0.2 6.7 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KNE01604.1 - 3.2e-05 23.6 18.6 0.1 12.5 1.0 5.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.2 KNE01604.1 - 0.042 14.0 1.1 0.042 14.0 0.8 5.6 5 1 0 5 5 5 0 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KNE01604.1 - 0.83 9.8 36.6 0.92 9.6 0.2 6.5 4 1 2 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding Ribosomal_L31 PF01197.13 KNE01604.1 - 5.8 6.9 9.3 2.1 8.4 0.2 3.4 2 1 1 3 3 3 0 Ribosomal protein L31 PAT1 PF09770.4 KNE01607.1 - 1.5e-191 638.7 11.2 6e-189 630.1 7.8 2.0 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Chorismate_bind PF00425.13 KNE01608.1 - 5.8e-69 232.2 0.0 8.9e-69 231.6 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 KNE01608.1 - 4.6e-34 117.5 0.0 1.2e-33 116.1 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 KNE01608.1 - 2.8e-13 50.0 0.0 9.8e-13 48.3 0.0 1.9 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 KNE01608.1 - 5.3e-08 32.5 0.0 1.1e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 Peptidase C26 DUF1266 PF06889.6 KNE01608.1 - 0.12 12.2 0.0 0.49 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) Uso1_p115_head PF04869.9 KNE01609.1 - 1.1e-84 283.9 0.1 2.9e-84 282.5 0.0 1.8 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region HEAT_2 PF13646.1 KNE01609.1 - 6.1e-05 23.2 0.3 0.028 14.7 0.0 3.4 2 0 0 2 2 2 1 HEAT repeats COG5 PF10392.4 KNE01609.1 - 0.00083 19.3 7.7 0.00083 19.3 5.3 3.5 1 1 2 3 3 3 1 Golgi transport complex subunit 5 HEAT PF02985.17 KNE01609.1 - 0.078 13.0 0.1 7.8 6.8 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat Spc7 PF08317.6 KNE01609.1 - 0.82 8.2 43.3 1.1 7.8 6.3 2.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Filament PF00038.16 KNE01609.1 - 1.1 8.6 43.0 2.7 7.3 29.8 1.8 1 1 0 1 1 1 0 Intermediate filament protein Fib_alpha PF08702.5 KNE01609.1 - 1.1 9.3 37.7 0.1 12.7 6.6 4.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 KNE01609.1 - 1.3 8.1 13.9 1.4 8.0 2.4 2.7 1 1 0 2 2 2 0 Reovirus sigma C capsid protein IKI3 PF04762.7 KNE01610.1 - 4.1e-261 868.8 0.0 5.2e-261 868.4 0.0 1.1 1 0 0 1 1 1 1 IKI3 family WD40 PF00400.27 KNE01610.1 - 0.028 14.2 0.4 9.5 6.2 0.0 4.2 5 0 0 5 5 5 0 WD domain, G-beta repeat GSK-3_bind PF05350.7 KNE01610.1 - 0.036 13.5 0.0 0.078 12.4 0.0 1.5 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding GHL13 PF14883.1 KNE01610.1 - 0.087 11.9 1.0 0.24 10.5 0.7 1.7 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 V_ATPase_I PF01496.14 KNE01611.1 - 7.1e-271 900.4 9.6 8.6e-271 900.1 6.7 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family RIX1 PF08167.7 KNE01612.1 - 1.8e-19 69.9 4.1 2.2e-19 69.7 1.9 1.9 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis DUF3890 PF13029.1 KNE01612.1 - 0.039 14.0 0.2 0.14 12.2 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3890) QLQ PF08880.6 KNE01612.1 - 0.19 11.1 0.2 0.36 10.2 0.2 1.4 1 0 0 1 1 1 0 QLQ Apc5 PF12862.2 KNE01613.1 - 8.8e-26 89.5 1.7 3.2e-25 87.8 1.2 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 CDP-OH_P_transf PF01066.16 KNE01614.1 - 4.2e-20 71.9 5.1 4.2e-20 71.9 3.6 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ISK_Channel PF02060.10 KNE01614.1 - 1.3 8.6 5.1 0.57 9.7 0.6 2.1 2 0 0 2 2 2 0 Slow voltage-gated potassium channel RCC1_2 PF13540.1 KNE01615.1 - 3e-14 52.1 6.9 3e-07 29.8 0.1 3.9 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 KNE01615.1 - 4.1e-13 49.3 1.2 0.03 14.5 0.0 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat F-box PF00646.28 KNE01615.1 - 0.00081 18.9 0.0 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 F-box domain ORMDL PF04061.9 KNE01616.1 - 4.4e-56 188.2 4.2 5.2e-56 187.9 2.9 1.0 1 0 0 1 1 1 1 ORMDL family SHMT PF00464.14 KNE01617.1 - 2.8e-208 691.1 0.0 3.2e-208 690.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 KNE01617.1 - 2.2e-05 23.5 0.0 4.7e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KNE01617.1 - 0.00019 20.6 0.0 0.00029 20.0 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KNE01617.1 - 0.00083 18.1 0.0 0.0012 17.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Hexokinase_2 PF03727.11 KNE01618.1 - 9.1e-75 250.9 0.0 1.2e-74 250.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KNE01618.1 - 5.9e-66 221.7 0.0 8.7e-66 221.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF1769 PF08588.5 KNE01619.1 - 8.7e-20 70.4 0.1 1.6e-19 69.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Transaldolase PF00923.14 KNE01620.1 - 6.9e-98 327.3 1.2 7.8e-98 327.1 0.9 1.0 1 0 0 1 1 1 1 Transaldolase Surface_Ag_2 PF01617.12 KNE01620.1 - 0.065 12.4 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Surface antigen Flavokinase PF01687.12 KNE01621.1 - 1.7e-29 102.2 0.0 2.2e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase NRDE-2 PF08424.5 KNE01622.1 - 0.021 13.7 0.9 0.15 10.9 0.0 2.3 2 1 0 2 2 2 0 NRDE-2, necessary for RNA interference Suf PF05843.9 KNE01622.1 - 0.18 11.5 1.0 0.33 10.6 0.7 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ribosomal_L18ae PF01775.12 KNE01623.1 - 5.7e-56 187.7 0.7 5.7e-56 187.7 0.5 1.4 1 1 1 2 2 2 1 Ribosomal L18ae/LX protein domain FA_hydroxylase PF04116.8 KNE01624.1 - 3e-17 63.0 17.1 3e-17 63.0 11.9 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily GATase PF00117.23 KNE01625.1 - 2.3e-44 151.1 0.0 3e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 KNE01625.1 - 1.2e-43 147.7 0.0 2e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 KNE01625.1 - 1.5e-05 24.5 0.2 0.00054 19.4 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 Bul1_N PF04425.7 KNE01626.1 - 3.1e-107 358.8 1.4 3.1e-107 358.8 1.0 1.4 1 1 1 2 2 2 1 Bul1 N terminus Bul1_C PF04426.7 KNE01626.1 - 1.1e-11 44.4 0.0 4.6e-09 35.8 0.0 2.6 1 1 0 2 2 2 2 Bul1 C terminus DWNN PF08783.6 KNE01627.1 - 2e-25 88.5 0.3 6.8e-25 86.8 0.0 2.1 2 0 0 2 2 2 1 DWNN domain zf-CCHC PF00098.18 KNE01627.1 - 0.00056 19.7 2.7 0.00056 19.7 1.9 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.1 KNE01627.1 - 0.00079 18.8 3.1 0.0015 17.9 2.2 1.4 1 0 0 1 1 1 1 Zinc knuckle ERM PF00769.14 KNE01627.1 - 0.004 16.7 0.3 0.004 16.7 0.2 1.9 1 1 1 2 2 2 1 Ezrin/radixin/moesin family Zn_Tnp_IS1595 PF12760.2 KNE01627.1 - 0.0081 15.9 2.6 0.65 9.8 0.0 2.6 2 0 0 2 2 2 1 Transposase zinc-ribbon domain zf-CCHC_3 PF13917.1 KNE01627.1 - 0.015 15.0 0.3 0.052 13.2 0.2 2.0 2 0 0 2 2 2 0 Zinc knuckle eIF3g PF12353.3 KNE01627.1 - 0.087 12.7 0.2 0.087 12.7 0.1 2.7 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G TF_Zn_Ribbon PF08271.7 KNE01627.1 - 0.42 9.9 4.2 0.77 9.1 0.1 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding Nup160 PF11715.3 KNE01628.1 - 4e-24 84.6 1.6 5.2e-16 57.8 0.2 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 TAP42 PF04177.7 KNE01629.1 - 7.7e-71 238.7 6.3 8.7e-71 238.6 4.4 1.0 1 0 0 1 1 1 1 TAP42-like family TFIIA_gamma_C PF02751.9 KNE01630.1 - 2.7e-26 91.1 2.0 3.7e-26 90.6 1.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 KNE01630.1 - 4.5e-23 80.5 0.2 6.2e-23 80.1 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain HMG_box PF00505.14 KNE01633.1 - 2.1e-21 75.9 0.8 2.3e-21 75.8 0.6 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KNE01633.1 - 2.5e-14 53.3 0.6 2.8e-14 53.2 0.4 1.0 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 KNE01633.1 - 0.00026 20.7 1.8 0.0003 20.5 1.2 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box 5 CHDNT PF08073.7 KNE01633.1 - 0.095 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 CHDNT (NUC034) domain CUE PF02845.11 KNE01634.1 - 7.9e-09 34.8 0.3 1.6e-08 33.8 0.2 1.6 1 0 0 1 1 1 1 CUE domain TTL PF03133.10 KNE01635.1 - 1.3e-59 201.5 0.6 2.3e-59 200.7 0.4 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 KNE01635.1 - 4.5e-41 140.3 0.0 7.1e-41 139.6 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATP-grasp_4 PF13535.1 KNE01635.1 - 0.016 14.9 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_YheCD PF14398.1 KNE01635.1 - 0.05 12.3 0.0 4.5 5.9 0.0 2.2 2 0 0 2 2 2 0 YheC/D like ATP-grasp zf-Tim10_DDP PF02953.10 KNE01636.1 - 3e-17 61.6 0.3 4e-17 61.2 0.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 KNE01636.1 - 0.1 12.0 0.8 0.2 11.1 0.5 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) F_bP_aldolase PF01116.15 KNE01637.1 - 6.4e-97 324.1 0.0 7.2e-97 323.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Peptidase_C26 PF07722.8 KNE01637.1 - 0.06 12.7 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Peptidase C26 SNAP PF14938.1 KNE01637.1 - 0.1 11.6 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP Acetyltransf_1 PF00583.19 KNE01638.1 - 9.6e-14 51.1 0.0 1.8e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KNE01638.1 - 6.1e-08 32.7 0.0 1.1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KNE01638.1 - 1.3e-07 31.9 0.0 1.6e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KNE01638.1 - 1.8e-06 27.6 0.1 3.6e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 KNE01638.1 - 2.3e-06 27.5 0.1 3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KNE01638.1 - 6.7e-06 26.2 0.0 9.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KNE01638.1 - 0.00027 20.7 0.0 0.00065 19.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain RXT2_N PF08595.6 KNE01639.1 - 3.3e-32 111.3 0.7 3.3e-32 111.3 0.5 1.7 2 0 0 2 2 2 1 RXT2-like, N-terminal MFS_1 PF07690.11 KNE01644.1 - 1.1e-24 86.8 44.5 2.1e-19 69.4 21.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KNE01644.1 - 3.5e-05 22.5 16.5 0.002 16.7 0.7 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 KNE01644.1 - 0.0053 16.5 1.9 0.029 14.1 0.0 2.6 2 0 0 2 2 2 1 MFS_1 like family DUF973 PF06157.6 KNE01644.1 - 0.31 9.9 10.5 0.25 10.2 3.4 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF973) Form-deh_trans PF09163.6 KNE01644.1 - 2.2 7.8 5.1 1.6 8.2 0.3 2.7 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane Acetyltransf_6 PF13480.1 KNE01645.1 - 2.9e-09 36.9 0.0 6.2e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2678 PF10856.3 KNE01645.1 - 0.13 11.9 4.7 0.28 10.9 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) DUF3353 PF11833.3 KNE01645.1 - 3.3 7.1 9.5 28 4.0 1.8 4.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3353) CRAL_TRIO PF00650.15 KNE01648.1 - 8e-40 135.9 0.0 2e-39 134.6 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KNE01648.1 - 4.3e-09 36.4 0.0 1.3e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KNE01648.1 - 2.1e-06 27.7 0.0 9.4e-06 25.6 0.0 2.2 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DEP PF00610.16 KNE01649.1 - 1.6e-16 59.8 0.0 2.4e-15 56.0 0.0 2.5 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.18 KNE01649.1 - 7.4e-15 54.9 3.7 2.3e-13 50.1 0.1 3.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 KNE01649.1 - 1.7e-11 43.9 0.1 5.8e-11 42.2 0.1 1.9 1 0 0 1 1 1 1 RhoGAP domain DUF1487 PF07368.6 KNE01649.1 - 0.0077 15.4 2.3 1.4 8.1 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF1487) BAG PF02179.11 KNE01649.1 - 0.13 12.3 6.8 2.5 8.2 0.0 4.7 5 0 0 5 5 5 0 BAG domain ECH PF00378.15 KNE01656.1 - 6.2e-16 58.2 0.0 7.8e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Imm46 PF15585.1 KNE01656.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 46 NPR3 PF03666.8 KNE01657.1 - 8.5e-134 446.4 12.4 4.6e-118 394.6 7.6 2.8 2 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 MT0933_antitox PF14013.1 KNE01657.1 - 8.6 6.5 16.7 11 6.1 2.2 2.5 1 1 1 2 2 2 0 MT0933-like antitoxin protein PROCN PF08083.6 KNE01658.1 - 2.8e-212 704.5 7.1 4.4e-212 703.9 5.0 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 KNE01658.1 - 9e-122 404.7 0.7 1.8e-121 403.7 0.5 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 KNE01658.1 - 6.3e-88 292.1 1.4 1.1e-87 291.3 0.3 2.0 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 KNE01658.1 - 1.5e-72 242.2 1.4 3.6e-72 240.9 0.9 1.7 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 KNE01658.1 - 2.1e-68 228.1 0.1 4.2e-68 227.1 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 KNE01658.1 - 5e-44 149.0 0.0 1.3e-43 147.7 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 KNE01658.1 - 7.2e-42 141.1 0.0 3.1e-41 139.1 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.16 KNE01658.1 - 6.8e-06 25.8 0.0 1.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RVT_1 PF00078.22 KNE01658.1 - 6.1e-05 22.4 0.3 0.0051 16.1 0.0 2.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fanconi_C PF02106.10 KNE01660.1 - 0.023 13.1 0.0 0.026 12.9 0.0 1.0 1 0 0 1 1 1 0 Fanconi anaemia group C protein zf-C3HC4_3 PF13920.1 KNE01663.1 - 3.7e-06 26.4 13.7 6e-06 25.8 9.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Aminotran_1_2 PF00155.16 KNE01665.1 - 4e-36 124.7 0.0 5.3e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II NLE PF08154.7 KNE01665.1 - 0.031 14.3 0.1 0.2 11.7 0.0 2.3 1 1 1 2 2 2 0 NLE (NUC135) domain APC8 PF04049.8 KNE01666.1 - 4.6e-32 110.7 2.0 1.3e-31 109.2 1.4 1.8 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_11 PF13414.1 KNE01666.1 - 1.8e-19 69.1 22.5 1.3e-08 34.3 0.8 7.5 5 1 3 8 8 8 5 TPR repeat TPR_1 PF00515.23 KNE01666.1 - 2.3e-19 68.0 19.9 2.9e-05 23.4 0.0 7.1 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 KNE01666.1 - 3.9e-14 51.3 26.2 0.00012 21.6 0.0 9.0 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 KNE01666.1 - 2.3e-13 48.8 16.5 0.00031 20.3 0.0 7.8 6 1 2 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 KNE01666.1 - 1.2e-10 41.7 17.5 0.00051 20.6 0.0 7.6 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 KNE01666.1 - 6.4e-10 38.7 8.0 0.025 15.2 0.0 7.4 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 KNE01666.1 - 8e-10 38.5 21.2 0.0007 19.4 0.1 6.1 5 1 2 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 KNE01666.1 - 2.8e-05 24.3 3.6 3.5 8.0 0.1 5.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KNE01666.1 - 5.2e-05 22.7 0.2 1.1 9.2 0.0 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KNE01666.1 - 0.00011 22.2 31.4 0.07 13.2 1.9 6.8 4 3 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 Fungal_trans_2 PF11951.3 KNE01666.1 - 0.00043 19.0 0.5 0.038 12.6 0.1 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain TPR_17 PF13431.1 KNE01666.1 - 0.0005 20.0 9.6 0.2 11.9 0.0 5.8 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KNE01666.1 - 0.001 19.3 17.9 9.9 6.8 0.0 8.5 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_9 PF13371.1 KNE01666.1 - 0.001 18.8 0.3 0.21 11.4 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat ChAPs PF09295.5 KNE01666.1 - 0.0013 17.5 2.3 4.2 6.0 0.0 3.4 3 1 1 4 4 4 2 ChAPs (Chs5p-Arf1p-binding proteins) DUF3856 PF12968.2 KNE01666.1 - 0.017 14.9 0.6 0.9 9.3 0.2 3.2 1 1 2 3 3 3 0 Domain of Unknown Function (DUF3856) PAP_central PF04928.12 KNE01666.1 - 0.031 13.0 0.0 0.038 12.7 0.0 1.3 1 0 0 1 1 1 0 Poly(A) polymerase central domain Mit_ribos_Mrp51 PF11709.3 KNE01666.1 - 0.12 11.5 1.2 0.22 10.7 0.8 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit TPR_10 PF13374.1 KNE01666.1 - 0.65 10.0 4.5 12 5.9 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4398 PF14346.1 KNE01666.1 - 1.5 8.9 5.6 1.3 9.0 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) PX PF00787.19 KNE01667.1 - 0.017 14.8 1.8 0.064 13.0 1.3 1.8 1 1 0 1 1 1 0 PX domain YicC_N PF03755.8 KNE01667.1 - 0.43 10.5 0.1 0.43 10.5 0.1 4.0 3 1 1 4 4 4 0 YicC-like family, N-terminal region DASH_Hsk3 PF08227.6 KNE01667.1 - 0.79 9.9 0.0 0.79 9.9 0.0 2.8 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like Cytokin_check_N PF10407.4 KNE01667.1 - 1.9 8.1 6.4 0.38 10.3 0.3 2.6 3 0 0 3 3 3 0 Cdc14 phosphatase binding protein N-terminus MPC PF03650.8 KNE01668.1 - 4.2e-45 152.5 0.2 4.9e-45 152.3 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) ABC_membrane PF00664.18 KNE01669.1 - 2.6e-59 200.9 31.2 4e-31 108.4 7.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KNE01669.1 - 1.3e-52 177.7 0.0 1.9e-30 105.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KNE01669.1 - 2.4e-13 49.8 6.8 0.00046 19.4 0.3 4.3 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KNE01669.1 - 2.5e-07 30.8 0.1 0.0056 16.6 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 KNE01669.1 - 1.1e-06 28.5 0.4 0.035 14.0 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 KNE01669.1 - 2.3e-06 27.0 0.1 0.041 13.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 KNE01669.1 - 2.8e-05 24.5 0.1 0.26 11.7 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_21 PF13304.1 KNE01669.1 - 3.2e-05 24.0 4.9 1.6 8.6 0.0 4.9 3 2 2 5 5 4 2 AAA domain AAA_25 PF13481.1 KNE01669.1 - 6.4e-05 22.4 0.0 0.25 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KNE01669.1 - 0.00045 20.5 0.3 1.2 9.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain DUF87 PF01935.12 KNE01669.1 - 0.00049 19.9 0.2 0.088 12.6 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_10 PF12846.2 KNE01669.1 - 0.00051 19.5 2.0 0.78 9.1 0.2 3.3 2 1 1 3 3 3 2 AAA-like domain Zeta_toxin PF06414.7 KNE01669.1 - 0.00081 18.5 0.0 0.29 10.2 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 KNE01669.1 - 0.0013 18.8 0.1 0.79 9.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 KNE01669.1 - 0.0015 18.2 0.0 0.23 11.1 0.0 3.2 3 0 0 3 3 3 1 NACHT domain DUF258 PF03193.11 KNE01669.1 - 0.0016 17.6 0.1 2 7.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 KNE01669.1 - 0.0047 16.5 0.0 3 7.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KNE01669.1 - 0.0082 15.6 0.1 4.1 6.8 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 KNE01669.1 - 0.01 15.5 0.5 5.7 6.6 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.11 KNE01669.1 - 0.016 14.2 0.9 0.77 8.8 0.0 2.4 2 0 0 2 2 2 0 AIG1 family T2SE PF00437.15 KNE01669.1 - 0.017 14.0 0.0 2.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.18 KNE01669.1 - 0.019 14.8 3.1 2.3 8.0 0.0 3.1 3 0 0 3 3 2 0 Dynamin family DUF815 PF05673.8 KNE01669.1 - 0.019 13.8 0.2 0.28 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 KNE01669.1 - 0.021 13.7 1.1 2.7 6.7 0.0 3.3 5 0 0 5 5 2 0 NB-ARC domain Arch_ATPase PF01637.13 KNE01669.1 - 0.022 14.4 0.1 0.22 11.1 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase ArgK PF03308.11 KNE01669.1 - 0.053 12.2 0.0 7 5.3 0.0 2.3 2 0 0 2 2 2 0 ArgK protein cobW PF02492.14 KNE01669.1 - 0.062 12.7 0.5 2 7.7 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.22 KNE01669.1 - 0.068 12.6 0.1 1.6 8.0 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KNE01669.1 - 0.078 12.8 0.0 13 5.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KNE01669.1 - 0.096 13.5 1.4 23 5.8 0.5 3.3 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 KNE01669.1 - 0.096 12.8 0.0 11 6.2 0.0 3.4 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KNE01669.1 - 0.11 12.0 0.1 8.9 5.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 KNE01669.1 - 0.13 11.7 0.3 4.4 6.7 0.0 2.6 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Peptidase_M23 PF01551.17 KNE01669.1 - 0.18 11.8 0.0 0.46 10.5 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M23 Aconitase PF00330.15 KNE01672.1 - 9.1e-180 598.0 0.1 2.1e-179 596.8 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KNE01672.1 - 1.1e-45 154.9 0.0 2.7e-45 153.6 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Spermine_synth PF01564.12 KNE01673.1 - 1.9e-99 331.5 0.0 2.6e-99 331.1 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 KNE01673.1 - 0.002 17.7 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNE01673.1 - 0.0042 17.5 0.0 0.0075 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNE01673.1 - 0.022 15.3 0.0 0.037 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain XPA_C PF05181.7 KNE01674.1 - 4.4e-24 83.8 0.2 1.1e-23 82.5 0.2 1.7 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 KNE01674.1 - 0.00023 20.7 0.4 0.00023 20.7 0.3 2.1 2 0 0 2 2 2 1 XPA protein N-terminal Clathrin_lg_ch PF01086.12 KNE01674.1 - 0.13 12.2 0.2 0.13 12.2 0.2 2.2 2 0 0 2 2 2 0 Clathrin light chain zf-RanBP PF00641.13 KNE01674.1 - 0.53 9.4 6.4 1.6 7.9 0.1 2.8 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others HSP90 PF00183.13 KNE01677.1 - 2e-255 848.2 42.3 2.4e-255 847.9 29.3 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 KNE01677.1 - 1.3e-10 40.9 0.0 2.4e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KNE01677.1 - 2.8e-10 39.9 0.0 2.8e-10 39.9 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1510 PF07423.6 KNE01677.1 - 0.0053 16.1 13.3 0.0053 16.1 9.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) DUF2722 PF10846.3 KNE01677.1 - 0.97 8.3 11.3 0.075 12.0 4.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF2435 PF10363.4 KNE01678.1 - 1e-31 108.6 0.8 2.2e-28 97.9 0.1 3.9 3 0 0 3 3 3 2 Protein of unknown function (DUF2435) DUF2411 PF10304.4 KNE01678.1 - 1.8e-11 43.2 1.7 7e-11 41.3 1.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) DUF760 PF05542.6 KNE01678.1 - 0.21 11.7 3.1 39 4.5 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF760) Ank_2 PF12796.2 KNE01679.1 - 1.1e-22 80.1 4.0 3.5e-15 56.0 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KNE01679.1 - 5.2e-17 61.4 1.3 3.7e-09 36.5 0.1 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KNE01679.1 - 6.1e-16 57.3 1.2 1e-07 31.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KNE01679.1 - 1.3e-14 54.2 0.2 9.9e-14 51.4 0.0 2.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNE01679.1 - 6.6e-14 50.6 0.3 9.8e-06 25.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat GCV_T PF01571.16 KNE01679.1 - 0.045 13.1 0.1 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 Aminomethyltransferase folate-binding domain LRAT PF04970.8 KNE01679.1 - 0.072 13.0 0.5 0.14 12.0 0.3 1.5 1 1 0 1 1 1 0 Lecithin retinol acyltransferase DUF2430 PF10353.4 KNE01679.1 - 0.12 12.6 0.2 0.72 10.0 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2430) AFT PF08731.6 KNE01679.1 - 0.33 11.1 2.6 0.48 10.6 1.8 1.3 1 0 0 1 1 1 0 Transcription factor AFT eIF-5_eIF-2B PF01873.12 KNE01682.1 - 7.2e-45 151.6 0.1 1.1e-44 151.1 0.1 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 IF2_N PF04760.10 KNE01682.1 - 0.031 13.9 0.0 0.09 12.4 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region zf-HYPF PF07503.7 KNE01682.1 - 0.14 11.6 0.3 20 4.7 0.0 2.6 2 0 0 2 2 2 0 HypF finger Pkinase PF00069.20 KNE01684.1 - 2.8e-40 138.1 0.0 5.9e-40 137.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE01684.1 - 6.8e-15 54.8 0.0 3.4e-14 52.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNE01684.1 - 0.004 16.9 0.0 0.0057 16.4 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KNE01684.1 - 0.036 13.0 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Phe_tRNA-synt_N PF02912.13 KNE01684.1 - 0.074 12.7 0.0 0.95 9.2 0.0 2.3 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain Med9 PF07544.8 KNE01685.1 - 5.4e-22 77.3 0.3 8.6e-22 76.6 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 GspL_C PF12693.2 KNE01685.1 - 0.012 15.4 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 GspL periplasmic domain GvpG PF05120.7 KNE01685.1 - 0.022 14.5 1.0 0.049 13.4 0.3 1.9 1 1 0 1 1 1 0 Gas vesicle protein G Rhomboid PF01694.17 KNE01686.1 - 3.9e-12 46.4 12.5 3.9e-12 46.4 8.7 1.5 2 0 0 2 2 2 1 Rhomboid family Inp1 PF12634.2 KNE01687.1 - 1.5e-33 115.4 0.1 1.1e-32 112.6 0.1 2.6 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 Porin_3 PF01459.17 KNE01688.1 - 3.6e-53 180.6 0.7 4.4e-53 180.3 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic porin PFK PF00365.15 KNE01690.1 - 1.6e-164 545.6 2.2 4.3e-121 403.2 2.2 2.1 2 0 0 2 2 2 2 Phosphofructokinase Glyoxalase_2 PF12681.2 KNE01690.1 - 1e-05 26.0 0.0 2.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KNE01690.1 - 0.0087 16.0 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SHOCT PF09851.4 KNE01690.1 - 0.0091 15.4 0.0 0.029 13.8 0.0 1.9 1 0 0 1 1 1 1 Short C-terminal domain TBCC PF07986.7 KNE01691.1 - 6e-14 51.4 0.0 1.1e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C PDEase_II PF02112.10 KNE01691.1 - 0.059 12.2 0.1 0.08 11.8 0.1 1.1 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II TPP_enzyme_N PF02776.13 KNE01692.1 - 1.1e-23 83.5 0.0 2e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KNE01692.1 - 1.2e-18 67.1 0.0 2.5e-16 59.6 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KNE01692.1 - 2e-08 34.0 0.0 4.2e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TFIIE_beta PF02186.10 KNE01692.1 - 0.025 14.5 0.0 3.3 7.7 0.0 2.8 2 0 0 2 2 2 0 TFIIE beta subunit core domain AMP-binding PF00501.23 KNE01693.1 - 1.9e-63 214.3 0.0 1.3e-61 208.2 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme TIP49 PF06068.8 KNE01694.1 - 1e-175 584.2 4.6 1.2e-175 583.9 3.2 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KNE01694.1 - 2e-08 34.5 1.4 5.8e-05 23.2 0.0 3.1 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KNE01694.1 - 1.7e-06 27.2 2.9 0.0014 17.7 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KNE01694.1 - 2.7e-05 24.3 0.1 0.044 13.9 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 KNE01694.1 - 0.00016 21.7 0.5 0.0071 16.3 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 KNE01694.1 - 0.00095 19.0 0.1 3.6 7.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 KNE01694.1 - 0.0021 17.4 1.4 0.0068 15.8 0.2 2.1 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.10 KNE01694.1 - 0.0031 16.4 0.1 0.0058 15.5 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.16 KNE01694.1 - 0.0063 15.6 0.9 0.085 12.0 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KNE01694.1 - 0.011 15.7 0.1 0.034 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KNE01694.1 - 0.015 14.9 0.1 1.2 8.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KNE01694.1 - 0.024 14.3 0.2 0.065 12.9 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 KNE01694.1 - 0.057 13.7 0.2 0.23 11.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain Sipho_tail PF05709.6 KNE01694.1 - 0.07 12.2 0.2 0.12 11.4 0.1 1.4 1 0 0 1 1 1 0 Phage tail protein ATP-synt_C PF00137.16 KNE01695.1 - 2.4e-26 91.4 26.2 2.2e-16 59.4 4.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Polysacc_synt_3 PF13440.1 KNE01695.1 - 0.014 14.8 0.5 0.014 14.8 0.3 2.1 1 1 2 3 3 3 0 Polysaccharide biosynthesis protein TctB PF07331.6 KNE01695.1 - 4.9 6.8 15.5 93 2.6 10.8 2.2 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Mis14 PF08641.7 KNE01696.1 - 4.2e-20 72.2 4.9 4.2e-20 72.2 3.4 1.5 1 1 0 1 1 1 1 Kinetochore protein Mis14 like ADIP PF11559.3 KNE01696.1 - 0.0038 17.1 9.1 0.11 12.4 1.8 2.3 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding DUF706 PF05153.10 KNE01696.1 - 0.0046 16.3 0.0 0.0092 15.3 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF706) RolB_RolC PF02027.12 KNE01696.1 - 0.17 11.0 0.7 0.4 9.8 0.0 1.9 2 1 0 2 2 2 0 RolB/RolC glucosidase family IncA PF04156.9 KNE01696.1 - 4.3 6.8 14.9 29 4.1 10.3 2.0 1 1 1 2 2 2 0 IncA protein RasGAP_C PF03836.10 KNE01697.1 - 4.6e-39 133.3 9.3 4.6e-39 133.3 6.4 2.2 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.14 KNE01697.1 - 2.5e-27 95.8 2.0 2.5e-27 95.8 1.4 2.6 3 1 1 4 4 4 1 GTPase-activator protein for Ras-like GTPase DUF1900 PF08954.6 KNE01698.1 - 1.1e-49 167.4 0.0 2.1e-49 166.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) zf-met PF12874.2 KNE01699.1 - 0.014 15.5 0.5 0.023 14.9 0.1 1.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KNE01699.1 - 0.066 13.5 0.3 0.33 11.3 0.0 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KNE01699.1 - 0.068 13.5 0.3 0.068 13.5 0.2 1.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type LCAT PF02450.10 KNE01700.1 - 6.8e-108 361.0 0.0 1.2e-107 360.2 0.0 1.4 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 KNE01700.1 - 0.0037 17.0 0.0 0.0087 15.8 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 KNE01700.1 - 0.01 14.9 0.3 0.41 9.7 0.2 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF900 PF05990.7 KNE01700.1 - 0.077 12.3 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF1749 PF08538.5 KNE01700.1 - 0.092 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KNE01700.1 - 0.2 11.4 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Autophagy_N PF03986.8 KNE01701.1 - 2.3e-46 157.2 0.7 3.7e-46 156.5 0.5 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 KNE01701.1 - 7.8e-21 74.0 0.1 1.5e-20 73.0 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 KNE01701.1 - 2.3e-14 52.1 0.3 4.5e-14 51.2 0.2 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Whi5 PF08528.6 KNE01702.1 - 0.26 10.9 7.7 0.1 12.2 3.4 1.8 2 0 0 2 2 2 0 Whi5 like Aldo_ket_red PF00248.16 KNE01703.1 - 1.3e-43 148.8 0.0 1.5e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ERG2_Sigma1R PF04622.7 KNE01705.1 - 2.9e-79 265.3 0.5 3.4e-79 265.0 0.3 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein MatE PF01554.13 KNE01707.1 - 6.5e-54 181.9 37.6 5.2e-32 110.6 5.8 2.4 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 KNE01707.1 - 3.1e-06 27.0 2.5 3.1e-06 27.0 1.7 4.6 2 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain BBP1_C PF15272.1 KNE01708.1 - 0.0015 18.1 1.9 0.0015 18.1 1.3 1.6 2 0 0 2 2 2 1 Spindle pole body component BBP1, C-terminal YkyA PF10368.4 KNE01708.1 - 0.0058 16.0 1.6 0.007 15.7 1.1 1.2 1 0 0 1 1 1 1 Putative cell-wall binding lipoprotein TPR_MLP1_2 PF07926.7 KNE01708.1 - 0.054 13.2 2.6 0.1 12.3 1.8 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein COOH-NH2_lig PF14395.1 KNE01708.1 - 0.17 10.8 0.7 0.24 10.4 0.2 1.4 2 0 0 2 2 2 0 Phage phiEco32-like COOH.NH2 ligase-type 2 Cyclin_N PF00134.18 KNE01710.1 - 5.8e-28 97.0 0.1 1.3e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4586 PF15239.1 KNE01710.1 - 0.015 14.8 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4586) Rot1 PF10681.4 KNE01714.1 - 8.8e-92 306.2 0.0 1e-91 306.0 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal VHS PF00790.14 KNE01715.1 - 5.3e-29 100.6 0.2 1e-28 99.7 0.1 1.5 1 0 0 1 1 1 1 VHS domain FYVE PF01363.16 KNE01715.1 - 2.3e-18 65.8 2.1 4.8e-18 64.8 1.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger zf-C4H2 PF10146.4 KNE01715.1 - 0.00075 19.5 0.7 0.00075 19.5 0.5 3.3 1 1 1 3 3 3 1 Zinc finger-containing protein UIM PF02809.15 KNE01715.1 - 0.002 17.5 3.3 0.002 17.5 2.3 3.1 3 0 0 3 3 3 1 Ubiquitin interaction motif FYVE_2 PF02318.11 KNE01715.1 - 0.036 13.9 1.3 0.12 12.2 0.9 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger zf-AN1 PF01428.11 KNE01715.1 - 0.38 10.6 6.8 0.98 9.3 4.7 1.7 1 0 0 1 1 1 0 AN1-like Zinc finger OAD_gamma PF04277.8 KNE01715.1 - 8.6 6.8 5.5 6.2 7.2 0.6 2.5 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Orn_Arg_deC_N PF02784.11 KNE01716.1 - 1e-68 231.2 0.0 1.3e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KNE01716.1 - 1.4e-28 98.9 0.0 3.1e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 KNE01716.1 - 0.014 14.6 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel MoaC PF01967.16 KNE01716.1 - 0.043 13.4 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 MoaC family Metallophos PF00149.23 KNE01718.1 - 6.9e-44 149.6 0.1 1e-43 149.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Hid1 PF12722.2 KNE01720.1 - 1.7e-171 572.0 12.6 2e-171 571.8 8.7 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 KNE01720.1 - 4.3e-25 87.9 3.8 4.3e-24 84.6 2.7 2.1 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein WGG PF10273.4 KNE01721.1 - 5.6e-27 93.6 1.0 5.6e-27 93.6 0.7 1.8 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 AAA PF00004.24 KNE01722.1 - 6.8e-15 55.4 0.0 2.2e-14 53.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KNE01722.1 - 3.5e-10 40.1 0.0 1.5e-08 34.8 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KNE01722.1 - 1.2e-08 35.1 0.0 3e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain BAH PF01426.13 KNE01722.1 - 2.8e-06 27.0 0.0 6.1e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 BAH domain Arch_ATPase PF01637.13 KNE01722.1 - 6.9e-05 22.6 0.0 0.00028 20.6 0.0 2.0 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 KNE01722.1 - 0.00034 20.3 0.0 0.0012 18.5 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.1 KNE01722.1 - 0.0013 19.5 0.0 0.0059 17.4 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KNE01722.1 - 0.002 18.4 0.0 0.0075 16.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.6 KNE01722.1 - 0.0093 15.6 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 CDC6, C terminal PIF1 PF05970.9 KNE01722.1 - 0.017 14.1 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase Myc_N PF01056.13 KNE01722.1 - 0.035 13.2 3.3 0.072 12.2 2.3 1.5 1 0 0 1 1 1 0 Myc amino-terminal region NTPase_1 PF03266.10 KNE01722.1 - 0.038 13.6 0.2 0.09 12.4 0.1 1.7 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.1 KNE01722.1 - 0.13 12.0 0.2 0.43 10.3 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain Ras PF00071.17 KNE01723.1 - 4.7e-26 91.1 0.1 5.4e-26 90.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNE01723.1 - 2e-14 54.0 0.0 4e-14 53.1 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 KNE01723.1 - 0.00022 20.4 0.2 0.00028 20.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 KNE01723.1 - 0.00071 18.8 0.1 0.00082 18.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KNE01723.1 - 0.0063 15.9 0.0 0.0076 15.7 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ribosomal_S3Ae PF01015.13 KNE01726.1 - 1.6e-77 259.2 5.8 1.9e-77 259.0 4.0 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family C2 PF00168.25 KNE01727.1 - 5.3e-61 202.4 0.3 1.6e-19 69.5 0.0 5.5 5 0 0 5 5 5 5 C2 domain FKBP_C PF00254.23 KNE01729.1 - 3e-27 94.4 0.0 3e-27 94.4 0.0 2.5 3 0 0 3 3 3 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4045 PF13254.1 KNE01729.1 - 0.06 12.6 27.3 0.54 9.4 8.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) MIP-T3 PF10243.4 KNE01729.1 - 0.23 9.8 63.7 0.029 12.8 20.6 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Spore_coat_CotO PF14153.1 KNE01729.1 - 1.9 7.8 45.8 0.54 9.6 14.1 2.3 2 0 0 2 2 2 0 Spore coat protein CotO Rtf2 PF04641.7 KNE01729.1 - 3.7 6.6 46.1 0.45 9.6 8.3 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger DDHD PF02862.12 KNE01729.1 - 4.5 7.0 27.2 1.4 8.6 3.2 2.4 2 0 0 2 2 2 0 DDHD domain AAA_11 PF13086.1 KNE01729.1 - 4.6 6.7 19.3 0.31 10.5 1.0 2.3 2 0 0 2 2 2 0 AAA domain FLO_LFY PF01698.11 KNE01729.1 - 5.6 5.7 35.5 0.75 8.5 8.0 2.2 2 0 0 2 2 2 0 Floricaula / Leafy protein SprA-related PF12118.3 KNE01729.1 - 7.6 5.7 37.2 3.3 6.9 11.2 2.2 2 0 0 2 2 2 0 SprA-related family Xan_ur_permease PF00860.15 KNE01731.1 - 1.5e-71 240.9 27.5 2.1e-71 240.4 19.0 1.1 1 0 0 1 1 1 1 Permease family She9_MDM33 PF05546.6 KNE01732.1 - 4.2e-87 291.0 11.0 7.4e-87 290.2 7.6 1.3 1 0 0 1 1 1 1 She9 / Mdm33 family DUF3425 PF11905.3 KNE01732.1 - 0.089 12.6 0.7 0.18 11.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3425) PsbH PF00737.15 KNE01732.1 - 0.12 11.9 0.6 0.26 10.9 0.4 1.5 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Hpt PF01627.18 KNE01732.1 - 0.14 12.1 0.1 0.14 12.1 0.1 2.5 3 0 0 3 3 3 0 Hpt domain FliJ PF02050.11 KNE01732.1 - 0.28 11.2 0.2 0.28 11.2 0.1 3.5 3 1 0 3 3 3 0 Flagellar FliJ protein DRY_EERY PF09750.4 KNE01732.1 - 0.3 11.1 5.0 0.79 9.8 3.4 1.8 1 0 0 1 1 1 0 Alternative splicing regulator DUF4381 PF14316.1 KNE01732.1 - 2.9 7.9 7.1 0.48 10.5 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) OEP PF02321.13 KNE01732.1 - 6 6.4 14.1 3.4 7.2 1.3 3.0 3 1 0 3 3 3 0 Outer membrane efflux protein PI-PLC-X PF00388.14 KNE01733.1 - 5.3e-19 68.0 0.0 8.6e-19 67.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Ribonuc_red_sm PF00268.16 KNE01740.1 - 2.5e-124 413.8 3.0 3.2e-124 413.4 2.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Nop10p PF04135.7 KNE01741.1 - 0.05 13.3 0.1 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Nucleolar RNA-binding protein, Nop10p family DUF367 PF04034.8 KNE01742.1 - 5.1e-51 171.5 0.1 7.8e-51 170.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 KNE01742.1 - 7.3e-16 57.4 0.4 1.2e-15 56.7 0.3 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Hydantoinase_B PF02538.9 KNE01745.1 - 4e-189 629.2 0.2 7.7e-189 628.2 0.0 1.5 2 0 0 2 2 2 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KNE01745.1 - 2.4e-85 286.1 0.0 6.3e-85 284.7 0.0 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KNE01745.1 - 2.9e-48 163.6 0.3 1e-46 158.6 0.1 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region VPS9 PF02204.13 KNE01746.1 - 1.3e-10 41.2 0.0 1e-09 38.3 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.2 KNE01746.1 - 8e-06 26.1 0.9 1.1 9.6 0.1 4.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KNE01746.1 - 0.0027 17.8 2.2 0.035 14.3 0.1 3.8 3 1 0 3 3 3 1 Ankyrin repeats (many copies) TPR_11 PF13414.1 KNE01747.1 - 1.1e-21 76.2 8.7 3e-16 58.8 0.9 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KNE01747.1 - 4.6e-15 54.4 4.5 0.00015 21.2 0.5 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KNE01747.1 - 4.2e-12 45.0 5.1 0.00055 19.6 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 KNE01747.1 - 8.2e-09 34.9 1.0 0.003 17.6 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KNE01747.1 - 6.1e-08 33.1 2.2 0.0003 21.3 1.4 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KNE01747.1 - 4.6e-07 29.1 0.1 0.4 10.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KNE01747.1 - 1.6e-06 28.1 1.7 0.42 11.3 0.0 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 KNE01747.1 - 4.8e-05 23.6 3.0 0.22 11.9 0.7 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KNE01747.1 - 6e-05 22.5 6.7 0.033 13.9 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.12 KNE01747.1 - 0.0001 22.6 1.9 0.0046 17.2 1.3 2.3 1 1 0 1 1 1 1 Bacterial transcriptional activator domain TPR_12 PF13424.1 KNE01747.1 - 0.00018 21.4 4.6 0.0005 19.9 1.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KNE01747.1 - 0.0024 17.6 0.1 0.036 13.9 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TOM20_plant PF06552.7 KNE01747.1 - 0.012 15.2 0.5 0.022 14.3 0.4 1.4 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_6 PF13174.1 KNE01747.1 - 1 9.9 9.5 1.3 9.6 2.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 KNE01747.1 - 1.5 8.9 4.7 1.9 8.6 0.9 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat XPC-binding PF09280.6 KNE01747.1 - 8.4 5.9 9.4 11 5.5 1.9 2.5 2 0 0 2 2 2 0 XPC-binding domain Kinesin PF00225.18 KNE01748.1 - 7.2e-109 363.5 0.0 1.6e-108 362.3 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain RsbU_N PF08673.5 KNE01748.1 - 4.8 7.2 11.7 9.1 6.3 1.0 3.0 2 0 0 2 2 2 0 Phosphoserine phosphatase RsbU, N-terminal domain MAR_sialic_bdg PF10564.4 KNE01751.1 - 0.024 14.3 0.2 0.034 13.9 0.2 1.2 1 0 0 1 1 1 0 Sialic-acid binding micronemal adhesive repeat Sel1 PF08238.7 KNE01753.1 - 8.7e-37 124.7 24.8 2.8e-08 34.1 0.8 8.2 8 0 0 8 8 8 7 Sel1 repeat UQ_con PF00179.21 KNE01755.1 - 5.6e-28 97.1 0.0 8.2e-28 96.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KNE01755.1 - 0.0024 17.7 0.1 0.0047 16.8 0.1 1.6 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 KNE01755.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B DUF4246 PF14033.1 KNE01756.1 - 1e-129 433.4 0.3 6.9e-129 430.7 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) DUF1837 PF08878.6 KNE01756.1 - 0.0091 15.6 0.1 0.02 14.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1837) Imm15 PF15590.1 KNE01756.1 - 0.66 9.1 6.5 0.12 11.4 0.6 2.6 3 0 0 3 3 3 0 Immunity protein 15 Methyltransf_11 PF08241.7 KNE01757.1 - 2.7e-17 63.0 0.0 1.1e-16 61.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNE01757.1 - 9.2e-17 61.0 0.3 1.4e-16 60.4 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNE01757.1 - 4.8e-16 58.9 0.0 8.3e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNE01757.1 - 6.7e-15 55.3 0.0 5.7e-14 52.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNE01757.1 - 1.6e-13 51.2 0.0 3.6e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KNE01757.1 - 1.9e-11 43.5 0.0 2.8e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KNE01757.1 - 2e-11 44.1 0.1 5.3e-11 42.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNE01757.1 - 3.4e-06 27.0 0.0 6.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KNE01757.1 - 2e-05 24.0 0.0 3.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.6 KNE01757.1 - 0.00023 20.2 0.0 0.00048 19.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) PrmA PF06325.8 KNE01757.1 - 0.03 13.4 0.0 0.16 11.0 0.0 1.8 1 1 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 KNE01757.1 - 0.032 13.9 0.0 0.075 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CmcI PF04989.7 KNE01757.1 - 0.047 12.9 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase DUF938 PF06080.7 KNE01757.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_31 PF13847.1 KNE01759.1 - 1.5e-18 66.8 0.0 2.2e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNE01759.1 - 1.1e-15 57.8 0.0 2.4e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNE01759.1 - 1.6e-14 54.1 0.0 3e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNE01759.1 - 2e-13 50.3 0.0 3.1e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNE01759.1 - 4.1e-13 49.9 0.0 8.8e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNE01759.1 - 3.2e-11 43.4 0.0 6.7e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KNE01759.1 - 1.5e-09 37.3 0.0 2.6e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KNE01759.1 - 4.5e-07 29.9 0.0 8.4e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KNE01759.1 - 0.00011 21.9 0.0 0.00022 20.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KNE01759.1 - 0.0032 16.8 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KNE01759.1 - 0.039 12.9 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase NNMT_PNMT_TEMT PF01234.12 KNE01759.1 - 0.067 12.1 0.0 0.19 10.6 0.0 1.7 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family FmrO PF07091.6 KNE01759.1 - 0.1 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) PCMT PF01135.14 KNE01759.1 - 0.15 11.5 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pkinase PF00069.20 KNE01761.1 - 1.5e-31 109.5 0.0 2.3e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE01761.1 - 5.9e-12 45.2 0.0 8.6e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNE01761.1 - 0.00043 20.1 0.2 0.068 12.9 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KNE01761.1 - 0.0013 17.8 0.0 0.0021 17.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KNE01761.1 - 0.19 10.4 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-AN1 PF01428.11 KNE01762.1 - 4.9e-10 39.1 9.5 8.2e-10 38.3 6.6 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger RNase_P_p30 PF01876.11 KNE01763.1 - 8.4e-44 148.4 0.0 1.2e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Elongin_A PF06881.6 KNE01764.1 - 3.6e-18 65.9 0.0 6.7e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A CRAL_TRIO PF00650.15 KNE01765.1 - 2e-40 137.9 0.0 2.8e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KNE01765.1 - 6.9e-12 45.3 2.3 2.3e-11 43.6 1.6 2.0 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KNE01765.1 - 0.12 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain EXOSC1 PF10447.4 KNE01766.1 - 3.2e-30 103.9 0.0 6.9e-30 102.8 0.0 1.6 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 RelB_N PF12910.2 KNE01768.1 - 0.089 12.1 0.1 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Antitoxin of toxin-antitoxin stability system N-terminal Globin PF00042.17 KNE01772.1 - 6.9e-06 26.3 0.0 2e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Globin DUF3824 PF12868.2 KNE01779.1 - 0.061 14.2 1.9 0.083 13.8 1.3 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Eapp_C PF10238.4 KNE01779.1 - 0.12 12.2 0.4 0.14 12.0 0.3 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein Atrophin-1 PF03154.10 KNE01779.1 - 0.51 8.4 5.5 0.68 8.0 3.8 1.2 1 0 0 1 1 1 0 Atrophin-1 family bZIP_1 PF00170.16 KNE01780.1 - 2.6e-06 27.3 7.3 6.9e-06 25.9 5.1 1.7 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KNE01780.1 - 1.1e-05 25.1 5.7 1.1e-05 25.1 4.0 1.6 1 1 0 1 1 1 1 Basic region leucine zipper Med4 PF10018.4 KNE01780.1 - 0.03 13.7 0.6 0.028 13.8 0.4 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 WEMBL PF05701.6 KNE01780.1 - 0.035 12.5 1.9 0.033 12.6 1.3 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light bZIP_Maf PF03131.12 KNE01780.1 - 0.05 13.9 1.9 0.054 13.7 1.3 1.0 1 0 0 1 1 1 0 bZIP Maf transcription factor Tower PF09121.5 KNE01780.1 - 0.09 12.7 1.8 0.11 12.4 0.1 2.0 1 1 1 2 2 2 0 Tower Tropomyosin_1 PF12718.2 KNE01780.1 - 0.16 11.7 4.4 0.27 11.0 3.1 1.5 1 1 0 1 1 1 0 Tropomyosin like TSC22 PF01166.13 KNE01780.1 - 0.59 10.1 2.9 1.1 9.2 2.0 1.5 1 1 0 1 1 1 0 TSC-22/dip/bun family DUF883 PF05957.8 KNE01781.1 - 0.00097 19.4 9.9 0.013 15.9 1.2 2.4 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 KNE01781.1 - 0.0092 15.5 2.9 0.023 14.2 2.0 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Vfa1 PF08432.5 KNE01781.1 - 0.048 13.6 10.7 0.06 13.3 7.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Cupin_8 PF13621.1 KNE01781.1 - 0.061 12.8 0.3 0.065 12.7 0.2 1.1 1 0 0 1 1 1 0 Cupin-like domain APG6 PF04111.7 KNE01781.1 - 0.061 12.3 6.8 0.081 11.9 4.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Borrelia_P83 PF05262.6 KNE01781.1 - 0.065 11.4 13.0 0.074 11.3 9.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein OmpH PF03938.9 KNE01781.1 - 0.081 12.8 10.4 0.12 12.3 7.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Prominin PF05478.6 KNE01781.1 - 0.096 10.2 1.7 0.12 9.8 1.2 1.0 1 0 0 1 1 1 0 Prominin DUF3584 PF12128.3 KNE01781.1 - 0.097 9.9 5.1 0.12 9.6 3.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3337 PF11816.3 KNE01781.1 - 0.21 10.9 6.7 0.24 10.7 4.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Mitofilin PF09731.4 KNE01781.1 - 0.26 9.8 13.5 0.31 9.6 9.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein AAA_13 PF13166.1 KNE01781.1 - 0.34 9.3 9.4 0.42 9.0 6.5 1.0 1 0 0 1 1 1 0 AAA domain Mnd1 PF03962.10 KNE01781.1 - 1 8.9 10.4 1.3 8.6 7.2 1.1 1 0 0 1 1 1 0 Mnd1 family NARP1 PF12569.3 KNE01781.1 - 1.3 7.6 14.5 1.6 7.4 10.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ATP-synt_B PF00430.13 KNE01781.1 - 1.4 8.7 18.3 2.9 7.6 11.5 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Seryl_tRNA_N PF02403.17 KNE01781.1 - 4.5 7.3 11.5 7.7 6.5 8.0 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Tom37_C PF11801.3 KNE01781.1 - 4.8 7.0 7.8 5.9 6.7 5.4 1.3 1 1 0 1 1 1 0 Tom37 C-terminal domain Vma12 PF11712.3 KNE01781.1 - 5.4 6.7 11.7 1.3e+02 2.1 8.1 2.1 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF913 PF06025.7 KNE01781.1 - 6.1 5.4 6.2 8.2 5.0 4.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ribosomal_S5 PF00333.15 KNE01782.1 - 6.2e-27 93.1 4.6 9.5e-27 92.5 1.9 2.2 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 KNE01782.1 - 6.9e-22 76.5 0.0 1.2e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain CoA_binding_3 PF13727.1 KNE01782.1 - 0.016 15.0 0.0 0.039 13.7 0.0 1.6 2 0 0 2 2 2 0 CoA-binding domain Fusion_gly PF00523.13 KNE01782.1 - 0.11 10.5 0.2 0.15 10.0 0.2 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 Nab2 PF11517.3 KNE01783.1 - 0.00086 19.3 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Ribosomal_60s PF00428.14 KNE01783.1 - 0.41 11.0 5.0 0.67 10.3 1.4 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-CCCH_2 PF14608.1 KNE01783.1 - 0.67 10.0 49.5 0.13 12.2 3.5 5.4 5 0 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type Cpn60_TCP1 PF00118.19 KNE01784.1 - 3.4e-132 441.5 11.2 4e-132 441.2 7.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Transposase_23 PF03017.9 KNE01784.1 - 0.046 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 TNP1/EN/SPM transposase tRNA-synt_2 PF00152.15 KNE01785.1 - 6.2e-83 278.3 1.2 1.4e-82 277.2 0.8 1.6 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KNE01785.1 - 0.0001 22.0 0.2 0.0002 21.1 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KNE01785.1 - 0.13 11.4 2.4 0.99 8.5 0.0 2.5 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) Taq-exonuc PF09281.5 KNE01785.1 - 3.3 7.8 6.7 8.9 6.4 4.5 1.9 1 1 0 1 1 1 0 Taq polymerase, exonuclease ArsR PF09824.4 KNE01786.1 - 0.024 13.9 0.0 0.026 13.8 0.0 1.0 1 0 0 1 1 1 0 ArsR transcriptional regulator GSH_synth_ATP PF03917.12 KNE01789.1 - 6.3e-113 377.1 0.0 7.4e-113 376.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 KNE01789.1 - 2.2e-39 133.7 0.0 4e-39 132.9 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase ATP-grasp_4 PF13535.1 KNE01789.1 - 0.074 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain DUF2102 PF09875.4 KNE01792.1 - 0.05 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) EcoEI_R_C PF08463.5 KNE01792.1 - 0.081 12.7 3.8 0.084 12.7 0.7 2.1 2 0 0 2 2 2 0 EcoEI R protein C-terminal YtxH PF12732.2 KNE01792.1 - 7.6 6.9 6.7 1.8 9.0 0.1 2.7 2 1 0 2 2 2 0 YtxH-like protein DUF2340 PF10209.4 KNE01793.1 - 1.5e-48 164.0 1.7 1.7e-48 163.8 1.2 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) CH PF00307.26 KNE01794.1 - 4e-16 58.9 10.0 9.5e-12 44.9 0.2 4.4 5 1 0 5 5 5 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KNE01794.1 - 0.003 17.1 0.8 0.046 13.3 0.2 3.4 2 1 0 2 2 2 1 CAMSAP CH domain Pkinase PF00069.20 KNE01795.1 - 4.9e-54 183.1 0.0 5.8e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE01795.1 - 2e-17 63.1 0.0 4e-17 62.1 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KNE01795.1 - 1.3e-06 28.3 0.0 3.6e-05 23.6 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNE01795.1 - 0.00099 18.7 0.3 0.0019 17.7 0.2 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 KNE01795.1 - 0.1 11.5 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Ribosomal_L18e PF00828.14 KNE01797.1 - 6e-18 65.4 0.1 1.7e-17 63.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 DUF3629 PF12302.3 KNE01797.1 - 0.039 13.3 0.1 0.37 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3629) Phage_30_3 PF08010.6 KNE01797.1 - 0.2 11.1 1.1 1.6 8.1 0.1 2.2 2 0 0 2 2 2 0 Bacteriophage protein GP30.3 UPF0150 PF03681.10 KNE01799.1 - 0.0046 16.5 3.8 7.6 6.2 0.0 3.8 4 0 0 4 4 4 3 Uncharacterised protein family (UPF0150) Peptidase_M22 PF00814.20 KNE01799.1 - 0.091 12.2 0.0 15 4.9 0.0 2.6 3 0 0 3 3 3 0 Glycoprotease family Prenyltrans PF00432.16 KNE01800.1 - 6e-22 76.8 4.1 1.8e-07 30.6 0.1 4.5 4 1 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 KNE01800.1 - 2.1e-20 72.7 0.1 8.7e-14 51.4 0.0 4.6 3 2 1 4 4 4 3 Prenyltransferase-like Prenyltrans_2 PF13249.1 KNE01800.1 - 5.3e-19 68.6 0.0 1.7e-11 44.4 0.0 4.6 2 1 2 4 4 4 4 Prenyltransferase-like Pec_lyase PF09492.5 KNE01800.1 - 0.0027 16.9 0.4 0.25 10.5 0.0 3.2 2 1 1 3 3 3 1 Pectic acid lyase Nrap PF03813.9 KNE01801.1 - 0 1154.9 0.1 0 1154.7 0.1 1.0 1 0 0 1 1 1 1 Nrap protein DUF4611 PF15387.1 KNE01801.1 - 0.85 9.8 9.1 2.1 8.5 6.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF1746 PF08508.5 KNE01802.1 - 1.7e-29 102.1 5.1 2.4e-29 101.6 3.6 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) ApbE PF02424.10 KNE01803.1 - 0.07 12.4 0.0 0.075 12.2 0.0 1.0 1 0 0 1 1 1 0 ApbE family RNA_pol_A_bac PF01000.21 KNE01804.1 - 1.4e-29 102.4 0.0 2.6e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KNE01804.1 - 4.8e-15 54.4 0.0 6.3e-15 54.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Hormone_4 PF00220.12 KNE01804.1 - 0.16 11.6 1.0 0.38 10.5 0.7 1.7 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain EMP24_GP25L PF01105.19 KNE01806.1 - 1.6e-45 155.1 1.0 1.9e-45 154.7 0.7 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Bot1p PF12298.3 KNE01807.1 - 4e-19 69.2 0.0 4.8e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Bot1p PF12298.3 KNE01808.1 - 3.1e-21 76.0 0.1 4e-21 75.7 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein ArsR PF09824.4 KNE01808.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 ArsR transcriptional regulator Pkinase PF00069.20 KNE01809.1 - 4.5e-39 134.1 0.0 2.9e-37 128.2 0.0 3.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE01809.1 - 1.9e-14 53.3 0.0 1.9e-11 43.5 0.0 3.0 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KNE01809.1 - 0.00014 21.6 0.0 0.00042 20.1 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Herpes_UL56 PF04534.7 KNE01809.1 - 0.052 13.2 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL56 protein Kinase-like PF14531.1 KNE01809.1 - 0.13 11.1 0.0 4.9 6.0 0.0 2.3 1 1 0 1 1 1 0 Kinase-like Brix PF04427.13 KNE01812.1 - 1.3e-31 109.7 2.3 1.7e-31 109.4 1.6 1.1 1 0 0 1 1 1 1 Brix domain Nucleoporin_C PF03177.9 KNE01813.1 - 1.5e-65 221.8 21.6 2e-65 221.4 15.0 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KNE01813.1 - 1.2e-48 165.9 0.0 2.1e-48 165.1 0.0 1.4 1 0 0 1 1 1 1 Nup133 N terminal like DASH_Dad2 PF08654.5 KNE01814.1 - 5.6e-29 100.1 2.0 6.7e-29 99.9 1.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.5 KNE01814.1 - 0.052 13.1 1.2 0.079 12.5 0.8 1.3 1 0 0 1 1 1 0 DASH complex subunit Duo1 DUF4201 PF13870.1 KNE01814.1 - 0.074 12.4 1.9 0.097 12.0 1.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) HATPase_c_5 PF14501.1 KNE01814.1 - 0.12 12.1 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 GHKL domain Shugoshin_N PF07558.6 KNE01815.1 - 0.03 14.0 0.7 0.11 12.2 0.5 2.0 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region CCDC155 PF14662.1 KNE01815.1 - 0.032 13.8 4.6 0.049 13.2 3.2 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 TMF_DNA_bd PF12329.3 KNE01815.1 - 0.37 10.6 6.0 0.16 11.8 1.7 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Mnd1 PF03962.10 KNE01815.1 - 0.46 10.1 4.5 0.13 11.9 0.9 1.7 2 0 0 2 2 2 0 Mnd1 family Thymidylat_synt PF00303.14 KNE01816.1 - 1.2e-116 388.5 0.0 1.3e-116 388.3 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase HSP9_HSP12 PF04119.7 KNE01817.1 - 1.2e-23 82.8 7.4 1.4e-23 82.7 5.1 1.0 1 0 0 1 1 1 1 Heat shock protein 9/12 4HBT PF03061.17 KNE01818.1 - 1.7e-09 37.6 0.0 2.4e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Peptidase_C48 PF02902.14 KNE01819.1 - 8.7e-25 87.6 0.3 8.7e-25 87.6 0.2 2.7 3 0 0 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain Laminin_II PF06009.7 KNE01820.1 - 0.019 14.7 12.6 0.027 14.2 7.4 2.1 2 0 0 2 2 2 0 Laminin Domain II AAA_23 PF13476.1 KNE01820.1 - 0.062 13.6 9.4 0.13 12.6 6.5 1.6 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 KNE01820.1 - 0.15 11.0 17.0 0.25 10.3 11.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 KNE01820.1 - 0.99 7.7 11.9 1.5 7.1 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) BLOC1_2 PF10046.4 KNE01820.1 - 2.4 8.3 19.2 18 5.5 4.8 2.9 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4337 PF14235.1 KNE01820.1 - 7.2 6.4 9.3 12 5.6 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) UPF0449 PF15136.1 KNE01820.1 - 8.9 6.5 12.4 6.8 6.9 6.6 2.3 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 FAD_binding_3 PF01494.14 KNE01821.1 - 1e-24 87.3 0.0 1.7e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KNE01821.1 - 3.1e-07 30.3 0.1 5.9e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 KNE01821.1 - 5.4e-06 25.4 0.1 2.4e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.22 KNE01821.1 - 0.00012 22.4 0.8 0.0019 18.5 0.1 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KNE01821.1 - 0.0029 16.3 0.0 1.2 7.7 0.0 2.6 2 1 1 3 3 3 2 Tryptophan halogenase DAO PF01266.19 KNE01821.1 - 0.0032 16.4 0.5 0.0074 15.2 0.4 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.11 KNE01821.1 - 0.0043 16.4 0.1 0.0077 15.6 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 KNE01821.1 - 0.0047 16.8 0.2 0.024 14.4 0.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KNE01821.1 - 0.037 13.6 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KNE01821.1 - 0.097 11.4 0.1 0.17 10.6 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Tim44 PF04280.10 KNE01822.1 - 1e-33 116.3 1.5 1.4e-33 115.9 0.1 1.9 2 1 0 2 2 2 1 Tim44-like domain SPX PF03105.14 KNE01822.1 - 0.16 11.7 3.1 1.8 8.2 2.1 2.2 2 1 0 2 2 2 0 SPX domain ArfGap PF01412.13 KNE01823.1 - 1.1e-34 118.6 0.1 2.5e-34 117.5 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Sugar_tr PF00083.19 KNE01826.1 - 1.6e-88 297.2 27.3 2e-88 296.9 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNE01826.1 - 5.9e-15 54.8 27.4 5.9e-15 54.8 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Mpv17_PMP22 PF04117.7 KNE01827.1 - 0.0002 20.9 1.3 0.00055 19.5 0.9 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family RseC_MucC PF04246.7 KNE01827.1 - 0.092 12.3 0.4 0.37 10.3 0.0 2.0 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC ADH_zinc_N PF00107.21 KNE01828.1 - 2e-09 37.1 0.0 3.3e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KNE01828.1 - 0.0012 18.5 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Amidohydro_1 PF01979.15 KNE01831.1 - 4e-30 105.6 0.2 1.4e-16 61.1 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KNE01831.1 - 9.1e-29 101.3 0.3 1e-16 61.8 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 KNE01831.1 - 1.5e-10 40.6 0.1 4.6e-10 39.1 0.1 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KNE01831.1 - 1.1e-06 28.1 0.0 0.0037 16.5 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase family MARCKS PF02063.12 KNE01831.1 - 0.043 13.6 0.3 0.082 12.7 0.2 1.4 1 0 0 1 1 1 0 MARCKS family NOA36 PF06524.7 KNE01831.1 - 0.1 11.8 1.7 0.16 11.1 1.2 1.2 1 0 0 1 1 1 0 NOA36 protein BAF1_ABF1 PF04684.8 KNE01831.1 - 0.21 10.3 3.4 0.31 9.8 2.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3128 PF11326.3 KNE01832.1 - 1.5e-28 98.7 0.3 2.3e-28 98.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Ras PF00071.17 KNE01833.1 - 4.2e-23 81.5 0.0 4.9e-23 81.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Utp12 PF04003.7 KNE01835.1 - 1.8e-21 76.1 3.3 2.1e-21 75.8 0.4 2.3 2 0 0 2 2 2 1 Dip2/Utp12 Family ECH_C PF13766.1 KNE01835.1 - 0.0058 16.7 0.1 0.015 15.4 0.1 1.7 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region Glyco_transf_22 PF03901.12 KNE01836.1 - 3.9e-67 227.0 24.0 4.9e-67 226.7 16.7 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family TctB PF07331.6 KNE01836.1 - 0.0012 18.5 5.3 0.0012 18.5 3.7 2.3 2 1 0 2 2 2 1 Tripartite tricarboxylate transporter TctB family AAA PF00004.24 KNE01837.1 - 4.4e-46 156.3 0.1 1.2e-45 154.9 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KNE01837.1 - 4e-09 36.5 0.0 7.5e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KNE01837.1 - 1e-08 34.9 0.1 3.8e-08 33.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KNE01837.1 - 1.3e-07 31.8 0.1 5.8e-07 29.6 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KNE01837.1 - 6.8e-07 29.4 0.8 0.00011 22.3 0.6 2.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KNE01837.1 - 2.7e-05 24.0 0.0 7.3e-05 22.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain DUF815 PF05673.8 KNE01837.1 - 4.1e-05 22.6 0.0 7.1e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KNE01837.1 - 0.00014 22.6 0.5 0.00079 20.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KNE01837.1 - 0.00037 19.6 0.0 0.00072 18.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin RuvB_N PF05496.7 KNE01837.1 - 0.00041 19.4 0.0 0.00093 18.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 KNE01837.1 - 0.00062 19.5 0.0 0.0019 17.9 0.0 1.8 2 0 0 2 2 1 1 NTPase NACHT PF05729.7 KNE01837.1 - 0.0011 18.7 0.2 0.056 13.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_3 PF07726.6 KNE01837.1 - 0.0013 18.3 0.0 0.0067 16.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KNE01837.1 - 0.0014 18.3 0.1 0.0037 16.9 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KNE01837.1 - 0.0016 18.3 0.0 0.0034 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KNE01837.1 - 0.0033 16.8 0.8 0.061 12.7 0.0 2.4 1 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KNE01837.1 - 0.0035 17.3 0.0 0.0074 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KNE01837.1 - 0.0042 17.2 0.0 0.0085 16.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 KNE01837.1 - 0.006 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KNE01837.1 - 0.0065 15.6 0.0 0.015 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 KNE01837.1 - 0.0067 15.1 0.0 0.013 14.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus BCNT PF07572.7 KNE01837.1 - 0.0073 16.2 1.6 0.016 15.1 1.1 1.5 1 0 0 1 1 1 1 Bucentaur or craniofacial development AAA_11 PF13086.1 KNE01837.1 - 0.0074 15.8 0.0 0.017 14.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KNE01837.1 - 0.011 15.1 0.0 0.28 10.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.1 KNE01837.1 - 0.012 15.1 0.0 0.04 13.4 0.0 2.0 3 0 0 3 3 2 0 AAA domain IstB_IS21 PF01695.12 KNE01837.1 - 0.015 14.6 0.0 0.038 13.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein UPF0079 PF02367.12 KNE01837.1 - 0.017 14.7 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 KNE01837.1 - 0.018 15.4 0.3 0.68 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KNE01837.1 - 0.018 14.7 0.8 0.14 11.8 0.0 2.5 2 1 1 3 3 3 0 Archaeal ATPase AAA_18 PF13238.1 KNE01837.1 - 0.02 15.1 0.2 0.079 13.2 0.0 2.1 2 1 0 2 2 1 0 AAA domain KaiC PF06745.8 KNE01837.1 - 0.038 13.0 0.1 0.7 8.9 0.0 2.3 2 0 0 2 2 2 0 KaiC Bac_DnaA PF00308.13 KNE01837.1 - 0.04 13.5 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activ_2 PF14532.1 KNE01837.1 - 0.13 12.3 0.0 0.46 10.5 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 KNE01837.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.12 KNE01837.1 - 0.18 10.6 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Fmp27_WPPW PF10359.4 KNE01838.1 - 1.4e-108 363.3 8.0 1.4e-108 363.3 5.5 2.4 4 0 0 4 4 4 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.4 KNE01838.1 - 1.9e-103 346.7 18.5 3.8e-103 345.8 11.7 2.2 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27 PF10344.4 KNE01838.1 - 4e-77 259.7 33.2 4e-77 259.7 23.0 2.4 2 1 0 2 2 2 1 Mitochondrial protein from FMP27 Fmp27_GFWDK PF10347.4 KNE01838.1 - 4.2e-51 172.9 0.1 1.3e-50 171.3 0.1 1.9 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 KNE01838.1 - 4.6e-38 130.4 1.0 4.6e-38 130.4 0.7 3.1 5 0 0 5 5 5 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 KNE01838.1 - 1.3e-22 80.1 0.5 1.4e-21 76.8 0.0 3.2 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain DUF3618 PF12277.3 KNE01838.1 - 0.45 10.5 2.2 1 9.4 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) RabGAP-TBC PF00566.13 KNE01840.1 - 6.9e-50 169.4 0.2 1.5e-49 168.4 0.1 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 KNE01840.1 - 1.2e-09 37.5 0.3 3.8e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 GRAM domain Vps36_ESCRT-II PF11605.3 KNE01840.1 - 0.0091 15.7 0.0 0.034 13.9 0.0 2.0 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 EF-hand_7 PF13499.1 KNE01840.1 - 0.31 11.2 0.1 0.31 11.2 0.0 2.4 3 0 0 3 3 3 0 EF-hand domain pair TMEM247 PF15444.1 KNE01841.1 - 0.48 10.2 7.0 0.51 10.1 2.8 2.5 2 0 0 2 2 2 0 Transmembrane protein 247 DUF1770 PF08589.5 KNE01842.1 - 0.00027 21.4 0.3 0.00054 20.5 0.1 1.4 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1770) RNA_pol_A_bac PF01000.21 KNE01843.1 - 8.4e-30 103.2 0.0 1.4e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KNE01843.1 - 8.2e-15 53.6 0.0 1e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain His_biosynth PF00977.16 KNE01844.1 - 1.8e-26 92.8 0.0 2.7e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein Aldolase PF01081.14 KNE01844.1 - 0.038 13.1 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 KDPG and KHG aldolase DUF4602 PF15375.1 KNE01845.1 - 0.022 14.7 0.4 0.022 14.7 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4602) PLRV_ORF5 PF01690.12 KNE01845.1 - 0.61 9.1 6.7 0.67 9.0 4.6 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein CDC45 PF02724.9 KNE01845.1 - 3.6 5.5 14.2 5 5.0 9.8 1.2 1 0 0 1 1 1 0 CDC45-like protein XhlA PF10779.4 KNE01845.1 - 3.9 7.4 5.8 76 3.3 2.9 2.8 2 0 0 2 2 2 0 Haemolysin XhlA NAM-associated PF14303.1 KNE01845.1 - 5.3 7.3 17.8 0.46 10.7 9.0 1.7 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Cnd2 PF05786.9 KNE01847.1 - 2e-148 496.0 24.2 2.5e-148 495.7 16.8 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 MCR_alpha PF02249.12 KNE01847.1 - 0.097 12.6 3.3 0.073 13.0 0.4 2.0 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain ADH_zinc_N_2 PF13602.1 KNE01848.1 - 9.5e-15 55.6 0.0 4.7e-14 53.3 0.0 2.2 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KNE01848.1 - 1.7e-09 37.2 0.0 3.9e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KNE01848.1 - 0.0003 20.5 0.1 0.00078 19.1 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Peptidase_M41 PF01434.13 KNE01849.1 - 9.9e-72 240.8 0.0 1.5e-71 240.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KNE01849.1 - 9.1e-42 142.3 0.0 4.8e-41 140.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KNE01849.1 - 1.2e-05 25.4 0.0 3e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.8 KNE01849.1 - 7.8e-05 21.5 0.0 0.00015 20.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 KNE01849.1 - 0.00013 22.0 0.2 0.022 14.8 0.1 2.9 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KNE01849.1 - 0.0004 20.0 0.4 0.001 18.7 0.3 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KNE01849.1 - 0.00068 20.4 0.0 0.0019 19.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KNE01849.1 - 0.0011 18.4 1.2 0.093 12.1 0.4 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 KNE01849.1 - 0.0012 18.5 0.1 0.005 16.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KNE01849.1 - 0.0046 16.3 0.0 0.011 15.1 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein RuvB_N PF05496.7 KNE01849.1 - 0.0047 16.0 0.0 0.0095 15.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KNE01849.1 - 0.0091 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KNE01849.1 - 0.012 15.5 0.0 0.039 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 KNE01849.1 - 0.013 14.6 0.0 0.036 13.1 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 KNE01849.1 - 0.032 14.5 0.0 0.081 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KNE01849.1 - 0.034 13.3 0.3 0.07 12.2 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KNE01849.1 - 0.061 13.2 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KNE01849.1 - 0.1 11.6 0.1 0.41 9.7 0.0 1.9 2 0 0 2 2 2 0 KaiC PhoH PF02562.11 KNE01849.1 - 0.11 11.7 0.4 0.28 10.4 0.2 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.1 KNE01849.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.17 KNE01850.1 - 7.7e-07 28.6 0.0 1.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNE01850.1 - 2.8e-06 27.1 0.0 6.3e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNE01850.1 - 0.0032 17.2 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GET2 PF08690.5 KNE01850.1 - 2.4 7.3 10.0 4.2 6.5 0.6 2.3 1 1 1 2 2 2 0 GET complex subunit GET2 DUF1631 PF07793.6 KNE01850.1 - 5.9 4.9 7.7 9.8 4.1 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) MRP-L46 PF11788.3 KNE01851.1 - 3e-36 124.4 0.3 4.9e-36 123.7 0.2 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 COPIIcoated_ERV PF07970.7 KNE01852.1 - 3.6e-69 232.7 0.1 4.4e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KNE01852.1 - 1.9e-30 104.6 1.1 6.5e-30 102.9 0.2 2.0 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) WD40 PF00400.27 KNE01853.1 - 1e-18 66.3 1.9 3.7e-05 23.4 0.1 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 KNE01853.1 - 7.7e-06 25.7 0.0 2.4e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A CNH PF00780.17 KNE01853.1 - 0.042 13.2 0.0 0.66 9.3 0.0 2.1 2 0 0 2 2 2 0 CNH domain Cytochrom_D1 PF02239.11 KNE01853.1 - 0.047 11.9 0.0 0.12 10.5 0.0 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain Adaptin_N PF01602.15 KNE01854.1 - 1.3e-89 300.9 14.7 2.6e-89 299.9 10.2 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KNE01854.1 - 5.6e-10 39.3 2.8 5.6e-10 39.3 1.9 2.8 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KNE01854.1 - 0.025 15.0 0.2 4.2 7.9 0.0 3.3 2 0 0 2 2 2 0 HEAT-like repeat Iron_permease PF04120.7 KNE01854.1 - 4.7 6.8 8.8 6.6 6.3 0.1 3.0 3 0 0 3 3 3 0 Low affinity iron permease KxDL PF10241.4 KNE01855.1 - 6.7e-10 38.7 1.0 1.1e-09 38.0 0.7 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein Metallopep PF12044.3 KNE01856.1 - 1.6e-152 507.8 0.0 2e-152 507.5 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_3 PF13582.1 KNE01856.1 - 0.0023 18.4 0.1 0.0051 17.3 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KNE01856.1 - 0.0024 17.8 0.2 0.0046 16.8 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KNE01856.1 - 0.0079 16.2 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 KNE01856.1 - 0.014 14.2 0.1 0.028 13.3 0.1 1.4 1 0 0 1 1 1 0 Peptidase M66 Jacalin PF01419.12 KNE01856.1 - 0.019 14.8 0.0 0.065 13.1 0.0 1.9 2 0 0 2 2 2 0 Jacalin-like lectin domain Reprolysin_4 PF13583.1 KNE01856.1 - 0.027 13.9 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.6 KNE01856.1 - 0.12 12.0 0.2 0.24 11.1 0.2 1.4 1 0 0 1 1 1 0 Peptidase family M54 Tyr-DNA_phospho PF06087.7 KNE01857.1 - 3.4e-108 362.1 0.0 4.7e-108 361.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 KNE01857.1 - 8.4e-06 25.5 0.2 0.002 17.8 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain SMC_N PF02463.14 KNE01858.1 - 1.6e-59 200.8 32.9 8.5e-59 198.4 22.8 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KNE01858.1 - 1.7e-25 89.3 0.0 7.8e-25 87.1 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KNE01858.1 - 1.6e-13 51.2 16.5 1.8e-07 31.3 1.4 3.9 3 2 1 4 4 4 2 AAA domain AAA_23 PF13476.1 KNE01858.1 - 1.5e-09 38.5 22.6 1.5e-09 38.5 15.7 7.5 2 2 1 3 3 3 1 AAA domain BRCT PF00533.21 KNE01858.1 - 0.00062 19.8 0.1 1.1 9.5 0.0 3.3 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain AAA_29 PF13555.1 KNE01858.1 - 0.00069 19.1 0.1 0.0029 17.1 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain TBPIP PF07106.8 KNE01858.1 - 0.0017 17.9 12.6 0.0017 17.9 8.7 9.2 3 2 7 10 10 10 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tropomyosin_1 PF12718.2 KNE01858.1 - 0.0026 17.6 16.0 0.0026 17.6 11.1 7.5 3 2 4 8 8 8 1 Tropomyosin like ABC_tran PF00005.22 KNE01858.1 - 1.3 9.3 0.0 1.3 9.3 0.0 6.1 4 3 0 4 4 4 0 ABC transporter RseA_C PF03873.8 KNE01858.1 - 4.8 7.1 12.1 2.2 8.2 0.2 3.6 3 1 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain FA_desaturase PF00487.19 KNE01859.1 - 5e-41 140.8 28.7 6.3e-41 140.5 19.9 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KNE01859.1 - 6e-12 45.1 0.0 1.6e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NUFIP1 PF10453.4 KNE01860.1 - 1.1e-19 69.6 3.1 2.6e-19 68.4 2.2 1.6 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 KNE01860.1 - 0.00012 21.6 2.9 0.00019 21.0 2.0 1.2 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) APC_CDC26 PF10471.4 KNE01860.1 - 0.1 13.3 1.0 0.1 13.3 0.7 2.1 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 zf-CCCH_2 PF14608.1 KNE01860.1 - 2.3 8.3 6.0 12 6.0 4.2 2.1 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type tRNA-synt_2b PF00587.20 KNE01863.1 - 1.3e-35 122.5 0.0 2.3e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KNE01863.1 - 2.8e-23 82.0 8.1 2.8e-23 82.0 5.6 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain GED PF02212.13 KNE01863.1 - 0.052 13.4 3.0 0.13 12.1 2.1 1.6 1 0 0 1 1 1 0 Dynamin GTPase effector domain NPV_P10 PF05531.7 KNE01863.1 - 0.056 13.6 3.1 0.08 13.2 1.1 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Campylo_MOMP PF05538.6 KNE01863.1 - 0.13 10.5 0.1 0.19 10.0 0.0 1.1 1 0 0 1 1 1 0 Campylobacter major outer membrane protein WD40 PF00400.27 KNE01864.1 - 8.5e-28 95.2 12.1 4.9e-07 29.3 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 KNE01864.1 - 0.03 12.4 0.1 0.3 9.1 0.1 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Cytokin_check_N PF10407.4 KNE01865.1 - 5.6e-26 89.9 0.1 1.2e-25 88.9 0.1 1.6 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus Ribonuclease_3 PF00636.21 KNE01866.1 - 3.1e-06 27.6 0.2 1.2e-05 25.6 0.0 2.2 3 0 0 3 3 3 1 Ribonuclease III domain YliH PF10799.3 KNE01866.1 - 0.0015 18.2 0.1 0.0039 16.8 0.0 1.7 2 0 0 2 2 2 1 Biofilm formation protein (YliH/bssR) DUF3956 PF13104.1 KNE01867.1 - 0.13 11.8 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) Dicistro_VP4 PF11492.3 KNE01867.1 - 0.13 12.2 0.4 1.2 9.2 0.0 2.2 2 1 0 2 2 2 0 Cricket paralysis virus, VP4 DAO PF01266.19 KNE01868.1 - 3.5e-21 75.5 0.0 1e-20 74.0 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KNE01868.1 - 0.0045 16.7 0.0 0.0082 15.9 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KNE01868.1 - 0.021 13.7 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DUF2956 PF11169.3 KNE01868.1 - 0.038 13.9 0.0 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Thi4 PF01946.12 KNE01868.1 - 0.071 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 KNE01868.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amidase PF01425.16 KNE01869.1 - 7.3e-88 295.3 0.0 9.8e-88 294.9 0.0 1.2 1 0 0 1 1 1 1 Amidase Toxin_7 PF05980.7 KNE01870.1 - 0.065 13.2 1.3 0.1 12.6 0.9 1.3 1 0 0 1 1 1 0 Toxin 7 FAD_binding_8 PF08022.7 KNE01875.1 - 2e-19 69.4 0.0 3.8e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KNE01875.1 - 7.5e-19 68.1 0.0 1.1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KNE01875.1 - 1.1e-15 57.8 12.2 1.1e-15 57.8 8.5 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component HhH-GPD PF00730.20 KNE01876.1 - 1.6e-11 44.4 0.0 3.3e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Slx4 PF09494.5 KNE01878.1 - 0.021 14.5 0.4 0.032 13.9 0.1 1.5 1 1 0 1 1 1 0 Slx4 endonuclease PFEMP PF03011.10 KNE01878.1 - 0.26 11.6 4.1 0.27 11.5 2.9 1.1 1 0 0 1 1 1 0 PFEMP DBL domain Transthyretin PF00576.16 KNE01882.1 - 5.3e-27 93.9 0.1 1.8e-18 66.4 0.1 2.4 1 1 1 2 2 2 2 HIUase/Transthyretin family Stn1 PF10451.4 KNE01883.1 - 1.1e-12 47.4 0.0 1.8e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Telomere regulation protein Stn1 Methyltransf_8 PF05148.10 KNE01884.1 - 7.7e-62 208.7 6.0 1e-29 103.7 0.0 3.5 2 1 1 3 3 3 3 Hypothetical methyltransferase Methyltransf_11 PF08241.7 KNE01884.1 - 2.3e-07 31.2 0.1 3.5e-06 27.4 0.1 2.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNE01884.1 - 0.0002 20.9 0.2 0.089 12.3 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 KNE01884.1 - 0.018 15.3 0.0 0.088 13.1 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KNE01884.1 - 0.079 12.3 0.0 0.34 10.2 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain WD40 PF00400.27 KNE01885.1 - 2.1e-05 24.2 11.1 0.055 13.3 0.0 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat HECT PF00632.20 KNE01886.1 - 3.5e-93 312.2 0.1 5e-93 311.7 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KNE01886.1 - 1.1e-33 114.7 21.2 5e-11 42.2 3.0 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.25 KNE01886.1 - 5.1e-15 55.0 0.1 1.2e-14 53.9 0.1 1.6 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.20 KNE01888.1 - 8e-31 107.1 0.0 1.3e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE01888.1 - 5.1e-10 38.8 0.0 7.5e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNE01888.1 - 0.00011 21.9 0.0 0.046 13.4 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Protocadherin PF08374.6 KNE01890.1 - 0.022 14.3 2.4 0.022 14.3 1.7 1.0 1 0 0 1 1 1 0 Protocadherin MRG PF05712.8 KNE01891.1 - 2.8e-40 137.3 0.4 4.4e-40 136.6 0.3 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 KNE01891.1 - 4.5e-07 29.4 0.0 9.2e-07 28.4 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF2578 PF10843.3 KNE01892.1 - 1e-88 296.1 6.2 1.1e-88 295.9 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2578) Tim17 PF02466.14 KNE01894.1 - 7.2e-46 155.3 5.3 9.2e-46 155.0 3.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Sulf_transp PF04143.9 KNE01894.1 - 0.46 10.5 16.5 0.14 12.2 2.3 2.4 2 0 0 2 2 2 0 Sulphur transport Med4 PF10018.4 KNE01895.1 - 0.0058 16.0 2.1 0.0089 15.4 1.5 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 HSCB_C PF07743.8 KNE01895.1 - 0.048 14.1 2.9 0.076 13.4 2.0 1.3 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain DUF4404 PF14357.1 KNE01895.1 - 0.21 11.9 5.1 0.46 10.9 3.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Wbp11 PF09429.5 KNE01895.1 - 1.5 8.8 4.8 0.45 10.5 0.5 2.1 3 0 0 3 3 3 0 WW domain binding protein 11 Chitin_synth_1 PF01644.12 KNE01896.1 - 1.5e-77 258.9 0.1 2.9e-77 258.0 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KNE01896.1 - 4.2e-24 84.0 0.0 1.2e-23 82.5 0.0 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KNE01896.1 - 5.9e-24 84.3 5.3 5.9e-18 64.5 0.0 3.1 2 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KNE01896.1 - 4.2e-11 42.9 1.0 1.5e-10 41.0 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KNE01896.1 - 3.7e-05 23.6 0.0 0.0014 18.4 0.0 2.9 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KNE01896.1 - 0.019 14.6 0.0 2.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 A_deaminase PF00962.17 KNE01897.1 - 3.3e-75 253.0 0.0 4.1e-75 252.7 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase IGR PF09597.5 KNE01898.1 - 0.001 18.8 1.2 0.0029 17.4 0.8 1.8 1 0 0 1 1 1 1 IGR protein motif ABC2_membrane_3 PF12698.2 KNE01898.1 - 0.0054 15.8 1.2 0.0059 15.6 0.9 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein RolB_RolC PF02027.12 KNE01898.1 - 0.0078 15.3 0.1 0.0095 15.1 0.1 1.2 1 0 0 1 1 1 1 RolB/RolC glucosidase family Vasculin PF15337.1 KNE01898.1 - 0.028 14.8 0.3 0.11 12.9 0.0 1.9 1 1 1 2 2 2 0 Vascular protein family Vasculin-like 1 Inhibitor_I9 PF05922.11 KNE01898.1 - 0.045 14.3 0.8 0.088 13.3 0.6 1.6 1 1 0 1 1 1 0 Peptidase inhibitor I9 Cytochrom_B562 PF07361.6 KNE01898.1 - 0.05 14.0 2.6 0.077 13.4 1.8 1.4 1 0 0 1 1 1 0 Cytochrome b562 MtrB PF05440.7 KNE01898.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B SSF PF00474.12 KNE01898.1 - 0.073 11.7 0.1 0.085 11.4 0.1 1.1 1 0 0 1 1 1 0 Sodium:solute symporter family ImcF-related_N PF14331.1 KNE01898.1 - 0.082 11.7 0.1 0.14 11.0 0.1 1.3 1 0 0 1 1 1 0 ImcF-related N-terminal domain Spore_III_AF PF09581.5 KNE01898.1 - 0.29 10.9 3.7 0.5 10.1 2.6 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Atg8 PF02991.11 KNE01899.1 - 2.7e-47 159.0 0.1 3.2e-47 158.7 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KNE01899.1 - 6.3e-06 26.3 0.0 8.1e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 GatB_N PF02934.10 KNE01900.1 - 1.4e-96 322.7 0.0 1.8e-96 322.4 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 KNE01900.1 - 2.1e-24 85.9 0.1 4.2e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 GatB domain STE3 PF02076.10 KNE01901.1 - 9.4e-81 270.9 19.3 1.1e-80 270.7 13.4 1.0 1 0 0 1 1 1 1 Pheromone A receptor HEAT_EZ PF13513.1 KNE01903.1 - 1.2e-13 51.0 15.8 1.8e-06 28.2 0.2 9.9 7 2 5 12 12 12 2 HEAT-like repeat HEAT_2 PF13646.1 KNE01903.1 - 9.9e-13 48.1 6.8 0.00013 22.1 0.0 7.1 5 3 3 8 8 8 3 HEAT repeats IBN_N PF03810.14 KNE01903.1 - 1e-11 44.5 4.1 5.7e-09 35.7 0.4 4.2 3 0 0 3 3 3 2 Importin-beta N-terminal domain HEAT PF02985.17 KNE01903.1 - 2.7e-07 30.1 16.0 0.0034 17.3 0.1 9.2 11 0 0 11 11 11 2 HEAT repeat Vac14_Fab1_bd PF12755.2 KNE01903.1 - 5.5e-05 23.4 8.0 0.25 11.7 0.1 6.4 6 1 1 7 7 7 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 KNE01903.1 - 0.00041 20.0 0.0 6 6.5 0.0 4.6 4 0 0 4 4 4 2 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 KNE01903.1 - 0.00098 18.5 0.8 1.9 7.7 0.0 3.9 3 0 0 3 3 3 2 CLASP N terminal DEAD PF00270.24 KNE01904.1 - 7.5e-40 136.1 4.1 1e-39 135.7 2.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNE01904.1 - 8.3e-28 96.0 0.2 2.3e-27 94.6 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KNE01904.1 - 0.00012 21.7 0.1 0.00031 20.4 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KNE01904.1 - 0.0018 17.9 1.0 0.0066 16.0 0.7 1.9 1 1 0 1 1 1 1 AAA domain SNF2_N PF00176.18 KNE01904.1 - 0.0048 15.7 0.4 0.0048 15.7 0.3 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_22 PF13401.1 KNE01904.1 - 0.0067 16.5 0.7 0.022 14.8 0.5 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KNE01904.1 - 0.015 15.1 0.3 0.039 13.7 0.2 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 KNE01904.1 - 0.043 13.5 0.3 0.23 11.1 0.1 2.4 1 1 0 1 1 1 0 Flavivirus DEAD domain AAA_11 PF13086.1 KNE01904.1 - 0.055 13.0 1.3 0.11 11.9 0.9 1.7 1 1 0 1 1 1 0 AAA domain EF1G PF00647.14 KNE01904.1 - 0.062 13.0 0.2 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain PRK PF00485.13 KNE01905.1 - 1.7e-16 60.3 0.4 1.6e-14 53.9 0.2 2.1 1 1 1 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 KNE01905.1 - 0.00032 21.4 0.0 0.00075 20.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KNE01905.1 - 0.014 15.7 0.1 0.042 14.1 0.0 1.7 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KNE01905.1 - 0.092 11.8 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Nucleoporin_C PF03177.9 KNE01906.1 - 8.4e-117 391.1 10.4 1.2e-116 390.6 7.2 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KNE01906.1 - 3.4e-101 339.0 8.3 5.5e-101 338.3 5.7 1.4 1 0 0 1 1 1 1 Nup133 N terminal like Peptidase_M28 PF04389.12 KNE01908.1 - 4e-22 78.7 0.1 5.9e-22 78.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KNE01908.1 - 0.014 14.9 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 SSB PF00436.20 KNE01909.1 - 4.1e-15 55.5 0.1 4.9e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF3844 PF12955.2 KNE01913.1 - 1.2e-31 108.8 4.6 2e-31 108.1 3.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Bul1_C PF04426.7 KNE01913.1 - 0.035 13.2 1.2 0.058 12.5 0.3 1.6 1 1 0 1 1 1 0 Bul1 C terminus HTH_39 PF14090.1 KNE01913.1 - 0.11 12.0 0.0 0.49 9.9 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain EGF_CA PF07645.10 KNE01913.1 - 0.33 10.9 10.1 0.62 10.1 7.0 1.4 1 0 0 1 1 1 0 Calcium-binding EGF domain EGF PF00008.22 KNE01913.1 - 1.6 8.8 6.5 2.7 8.0 4.5 1.3 1 0 0 1 1 1 0 EGF-like domain EGF_3 PF12947.2 KNE01913.1 - 4.4 7.3 11.6 7.3 6.6 8.0 1.4 1 0 0 1 1 1 0 EGF domain Evr1_Alr PF04777.8 KNE01914.1 - 1.9e-28 98.1 0.3 3.3e-28 97.4 0.2 1.3 1 0 0 1 1 1 1 Erv1 / Alr family G-gamma PF00631.17 KNE01915.1 - 8.6e-16 57.4 0.0 9.6e-16 57.2 0.0 1.1 1 0 0 1 1 1 1 GGL domain Fcf2 PF08698.6 KNE01915.1 - 0.018 15.0 0.1 0.019 14.9 0.1 1.1 1 0 0 1 1 1 0 Fcf2 pre-rRNA processing V-SNARE_C PF12352.3 KNE01916.1 - 3.1e-14 52.8 0.6 3.1e-14 52.8 0.4 3.2 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus SopA_C PF13979.1 KNE01916.1 - 0.039 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 SopA-like catalytic domain Sec20 PF03908.8 KNE01916.1 - 0.22 11.2 6.4 7.4 6.3 0.0 3.1 2 1 1 3 3 3 0 Sec20 Phostensin_N PF13916.1 KNE01916.1 - 0.24 11.3 1.0 2.7 8.0 0.0 2.9 2 1 1 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal Prefoldin_2 PF01920.15 KNE01916.1 - 1.5 8.6 7.4 0.11 12.2 1.7 1.7 2 0 0 2 2 2 0 Prefoldin subunit V_ATPase_I PF01496.14 KNE01916.1 - 1.8 6.3 4.4 2.1 6.1 3.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.7 KNE01916.1 - 3 7.5 9.9 3.2 7.5 0.1 3.2 1 1 2 3 3 3 0 Laminin Domain II UPF0184 PF03670.8 KNE01916.1 - 4.5 7.5 6.8 1.2 9.4 0.4 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) Syntaxin_2 PF14523.1 KNE01916.1 - 6.1 6.9 10.2 5.3 7.1 3.4 2.7 1 1 1 2 2 2 0 Syntaxin-like protein Mnd1 PF03962.10 KNE01916.1 - 7.1 6.2 8.1 1.3 8.6 2.3 1.9 1 1 1 2 2 2 0 Mnd1 family DUF1691 PF07950.6 KNE01918.1 - 2.8e-33 114.1 1.9 7.6e-16 58.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) DUF2838 PF10998.3 KNE01918.1 - 0.011 15.5 1.2 0.011 15.5 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2838) Sdh_cyt PF01127.17 KNE01918.1 - 0.43 10.4 8.3 0.29 10.9 2.1 2.6 2 1 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit NifU_N PF01592.11 KNE01919.1 - 3.7e-56 188.4 0.2 4.5e-56 188.2 0.2 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Ribosomal_L18p PF00861.17 KNE01922.1 - 4.2e-45 152.7 0.0 4.2e-45 152.7 0.0 2.0 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KNE01922.1 - 5.7e-32 110.1 11.9 5.7e-32 110.1 8.2 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 KNE01922.1 - 0.0051 16.8 2.0 0.45 10.5 0.0 3.0 2 1 0 3 3 3 2 Threonine synthase N terminus DUF1160 PF06648.6 KNE01922.1 - 0.0056 16.4 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1160) MTP18 PF10558.4 KNE01923.1 - 2.2e-60 202.8 0.0 2.8e-60 202.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) 3-HAO PF06052.7 KNE01924.1 - 8.1e-67 223.3 0.1 9.1e-67 223.1 0.1 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 KNE01924.1 - 1.4e-06 27.6 0.0 2.2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Nudix_N_2 PF14803.1 KNE01924.1 - 0.0011 18.5 2.6 0.2 11.3 0.1 2.7 3 0 0 3 3 3 2 Nudix N-terminal DZR PF12773.2 KNE01924.1 - 0.0044 16.8 1.6 0.0057 16.4 0.5 1.7 2 0 0 2 2 2 1 Double zinc ribbon C1_1 PF00130.17 KNE01924.1 - 0.073 12.8 1.5 0.44 10.3 0.1 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ribbon_3 PF13248.1 KNE01924.1 - 0.24 10.6 1.8 4.1 6.7 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain ADK_lid PF05191.9 KNE01924.1 - 0.75 9.5 5.4 3.5 7.3 2.4 2.6 2 1 0 2 2 2 0 Adenylate kinase, active site lid zinc_ribbon_2 PF13240.1 KNE01924.1 - 1.2 8.7 4.9 2.7 7.5 0.2 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zf-RanBP PF00641.13 KNE01924.1 - 1.2 8.2 4.1 0.5 9.5 0.2 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-B_box PF00643.19 KNE01924.1 - 2.5 8.0 5.4 7.5 6.5 0.1 2.8 2 1 0 2 2 2 0 B-box zinc finger DUF2407_C PF13373.1 KNE01925.1 - 3.6e-38 130.6 0.1 6.1e-38 129.8 0.1 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 KNE01925.1 - 3.4e-15 56.0 0.3 8.1e-15 54.7 0.1 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 KNE01925.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family Rad60-SLD PF11976.3 KNE01925.1 - 0.084 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Mito_carr PF00153.22 KNE01927.1 - 5.5e-66 218.3 2.9 9.8e-24 82.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RIIa PF02197.12 KNE01927.1 - 0.076 12.4 0.0 3.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit DUF1741 PF08427.5 KNE01928.1 - 4.7e-09 36.0 0.3 1.1e-08 34.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) DPPIV_N PF00930.16 KNE01929.1 - 2e-60 204.2 2.5 3.2e-60 203.6 1.8 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KNE01929.1 - 8.5e-45 152.5 1.3 1.8e-44 151.5 0.9 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KNE01929.1 - 7.5e-11 41.9 0.0 2.4e-09 37.0 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNE01929.1 - 4.1e-06 26.8 0.0 0.00076 19.4 0.0 3.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 KNE01929.1 - 0.0007 19.0 0.1 0.0028 17.1 0.0 1.9 2 0 0 2 2 2 1 Putative esterase PAF-AH_p_II PF03403.8 KNE01929.1 - 0.046 12.0 0.1 0.1 10.8 0.0 1.5 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Noc2 PF03715.8 KNE01930.1 - 6.3e-121 402.8 6.6 6.3e-121 402.8 4.6 2.0 2 0 0 2 2 2 1 Noc2p family Zn_clus PF00172.13 KNE01931.1 - 5.4e-05 23.0 5.5 0.00011 21.9 3.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mu-like_gpT PF10124.4 KNE01931.1 - 0.056 12.3 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Mu-like prophage major head subunit gpT zf-RING_2 PF13639.1 KNE01932.1 - 2e-12 46.6 6.8 4.9e-12 45.4 4.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KNE01932.1 - 9e-08 32.0 7.2 2.1e-07 30.8 5.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KNE01932.1 - 1.1e-07 31.3 5.7 2.4e-07 30.3 4.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KNE01932.1 - 1.2e-07 31.7 3.5 1.2e-07 31.7 2.4 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KNE01932.1 - 1.5e-06 27.7 3.4 3e-06 26.8 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNE01932.1 - 1.9e-06 27.4 5.1 3.9e-06 26.4 3.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KNE01932.1 - 0.0005 19.8 1.8 0.001 18.8 1.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PA PF02225.17 KNE01932.1 - 0.00059 19.4 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-RING_UBOX PF13445.1 KNE01932.1 - 0.0055 16.3 5.9 0.0057 16.3 3.1 1.8 2 0 0 2 2 1 1 RING-type zinc-finger Rtf2 PF04641.7 KNE01932.1 - 0.013 14.7 0.1 0.021 14.0 0.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Prok-RING_1 PF14446.1 KNE01932.1 - 0.078 12.7 1.0 0.83 9.4 0.2 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 KNE01932.1 - 0.33 10.7 4.4 0.17 11.6 1.4 1.8 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RINGv PF12906.2 KNE01932.1 - 0.39 10.8 6.0 0.82 9.7 4.2 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 KNE01932.1 - 0.48 10.4 6.8 3.9 7.5 4.8 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain zf-Nse PF11789.3 KNE01932.1 - 1 8.9 4.5 2.1 7.9 3.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit C2 PF00168.25 KNE01934.1 - 5.5e-54 179.9 6.6 2.3e-15 56.2 0.2 4.5 4 0 0 4 4 4 4 C2 domain DUF2404 PF10296.4 KNE01934.1 - 0.011 15.8 0.0 0.044 13.9 0.0 2.0 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) DUF3810 PF12725.2 KNE01934.1 - 0.12 11.2 1.3 0.31 9.8 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) RNA_pol_Rpb2_6 PF00562.23 KNE01935.1 - 5.8e-118 394.0 0.5 9e-118 393.3 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KNE01935.1 - 4.4e-57 192.3 0.5 7.9e-57 191.4 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KNE01935.1 - 5.1e-38 130.4 0.5 1.1e-37 129.3 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KNE01935.1 - 6.6e-30 103.2 0.1 2e-29 101.6 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 KNE01935.1 - 1.1e-25 89.2 0.1 7.1e-25 86.5 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 KNE01935.1 - 7.9e-19 67.1 0.0 1.7e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KNE01935.1 - 2e-12 46.8 1.0 5.2e-12 45.5 0.7 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 KNE01935.1 - 0.0035 15.7 1.8 0.0045 15.3 0.1 1.8 2 0 0 2 2 2 1 Baculovirus Y142 protein Ribonuc_red_lgC PF02867.10 KNE01937.1 - 1.1e-201 671.0 0.0 1.3e-201 670.8 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KNE01937.1 - 1.2e-19 69.8 0.1 3.5e-19 68.3 0.1 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain NRDD PF13597.1 KNE01937.1 - 0.049 11.6 0.0 0.081 10.9 0.0 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase Tfb2 PF03849.9 KNE01938.1 - 6.3e-145 482.4 0.0 7.9e-145 482.0 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 KNE01938.1 - 2.4e-05 24.0 0.0 5.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Response_reg PF00072.19 KNE01940.1 - 4.5e-11 42.7 0.0 5.5e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain GTP1_OBG PF01018.17 KNE01941.1 - 7.3e-34 116.6 3.1 2.5e-24 85.7 1.1 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 KNE01941.1 - 2.4e-18 66.1 0.0 4.6e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KNE01941.1 - 4.8e-08 32.4 0.0 6.8e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.16 KNE01941.1 - 0.0051 16.0 0.0 0.013 14.7 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KNE01941.1 - 0.015 15.7 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 KNE01941.1 - 0.018 14.8 0.0 0.047 13.4 0.0 1.8 1 1 0 1 1 1 0 Dynamin family DUF3602 PF12223.3 KNE01941.1 - 0.037 14.4 0.1 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) Ras PF00071.17 KNE01941.1 - 0.071 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Ras family DEAD PF00270.24 KNE01942.1 - 1.4e-40 138.5 0.0 6e-40 136.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNE01942.1 - 4.2e-27 93.8 0.0 9.8e-27 92.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNE01942.1 - 0.00036 20.3 1.0 0.0051 16.6 0.0 2.9 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DUF202 PF02656.10 KNE01943.1 - 2.1e-12 47.0 0.5 2.1e-12 47.0 0.3 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF202) CopD PF05425.8 KNE01943.1 - 0.021 15.0 3.1 0.17 12.1 1.1 2.3 1 1 1 2 2 2 0 Copper resistance protein D Abhydrolase_9_N PF15420.1 KNE01943.1 - 0.045 13.5 0.6 0.052 13.3 0.4 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF3671 PF12420.3 KNE01943.1 - 0.083 12.8 0.7 0.12 12.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function PAZ PF02170.17 KNE01944.1 - 0.084 12.1 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 PAZ domain TFIIB PF00382.14 KNE01945.1 - 1.3e-45 153.0 0.2 1.1e-22 79.6 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 KNE01945.1 - 1.1e-22 80.0 0.2 1.1e-22 80.0 0.2 3.5 2 1 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 KNE01945.1 - 5.7e-07 28.7 0.3 1.2e-06 27.6 0.2 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 KNE01945.1 - 6.8e-05 22.4 0.0 0.45 10.0 0.0 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain SDA1 PF05285.7 KNE01946.1 - 3.2e-103 345.4 35.4 3.2e-103 345.4 24.6 2.1 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.7 KNE01946.1 - 2.4e-24 85.3 0.2 7.9e-24 83.7 0.1 2.0 1 0 0 1 1 1 1 NUC130/3NT domain HMG_box PF00505.14 KNE01947.1 - 9.4e-10 38.6 1.0 9.4e-10 38.6 0.7 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KNE01947.1 - 1.8e-06 28.2 0.2 7.7e-06 26.1 0.1 2.3 1 0 0 1 1 1 1 HMG-box domain Acyl_transf_1 PF00698.16 KNE01949.1 - 6.8e-13 48.6 0.0 7.9e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Acyl transferase domain Tetraspannin PF00335.15 KNE01950.1 - 0.055 12.7 0.7 0.059 12.6 0.5 1.1 1 0 0 1 1 1 0 Tetraspanin family Ion_trans PF00520.26 KNE01950.1 - 0.12 11.5 5.1 0.15 11.3 3.6 1.3 1 1 0 1 1 1 0 Ion transport protein FTHFS PF01268.14 KNE01951.1 - 5.2e-261 866.4 0.4 7e-261 866.0 0.2 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 KNE01951.1 - 1.9e-63 212.3 2.4 2.8e-63 211.8 0.6 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KNE01951.1 - 9.5e-37 125.6 1.1 2e-36 124.5 0.7 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AlgF PF11182.3 KNE01952.1 - 0.11 12.1 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Alginate O-acetyl transferase AlgF PTR2 PF00854.16 KNE01953.1 - 6.7e-55 186.3 14.9 8.6e-55 186.0 10.4 1.1 1 0 0 1 1 1 1 POT family DUF4134 PF13572.1 KNE01953.1 - 0.00078 19.5 0.2 0.01 15.9 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4134) Peptidase_M3 PF01432.15 KNE01956.1 - 2.1e-147 491.8 5.1 2.1e-147 491.8 3.5 1.7 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M50B PF13398.1 KNE01956.1 - 0.018 14.4 1.7 0.29 10.5 0.2 2.2 2 0 0 2 2 2 0 Peptidase M50B-like DUF3961 PF13106.1 KNE01956.1 - 0.34 10.5 2.4 38 3.9 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3961) tRNA-synt_2b PF00587.20 KNE01957.1 - 1.1e-69 233.5 0.1 2.1e-69 232.5 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KNE01957.1 - 1.4e-23 82.5 0.1 9e-23 80.0 0.0 2.5 2 0 0 2 2 2 1 Anticodon binding domain Pyr_redox_3 PF13738.1 KNE01959.1 - 9.4e-17 61.7 0.0 6.1e-16 59.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KNE01959.1 - 9.1e-14 50.5 0.6 5.1e-10 38.1 0.3 2.9 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KNE01959.1 - 4.4e-08 32.4 0.3 2.2e-06 26.8 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KNE01959.1 - 5.2e-06 26.3 0.0 1.3e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KNE01959.1 - 0.00015 21.7 0.0 0.003 17.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KNE01959.1 - 0.0084 15.8 0.0 0.67 9.7 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 KNE01959.1 - 0.083 12.9 0.0 1.5 8.9 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase ABA_GPCR PF12430.3 KNE01961.1 - 3.4e-48 163.3 10.0 8e-48 162.1 6.9 1.6 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 KNE01961.1 - 3e-13 49.6 0.0 7.5e-13 48.3 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) ERGIC_N PF13850.1 KNE01961.1 - 0.043 13.7 0.2 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF1625 PF07787.7 KNE01961.1 - 0.19 10.9 8.9 1.1 8.4 0.1 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF1625) Mhr1 PF12829.2 KNE01962.1 - 3.3e-33 113.3 0.4 5.6e-33 112.6 0.3 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Fungal_trans PF04082.13 KNE01963.1 - 1.2e-06 27.5 0.3 6.5e-06 25.2 0.2 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNE01963.1 - 1.3e-05 24.9 12.7 2e-05 24.3 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MCC-bdg_PDZ PF10506.4 KNE01963.1 - 0.28 11.0 2.4 0.44 10.4 0.7 2.0 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Radical_SAM PF04055.16 KNE01965.1 - 9.6e-23 81.1 0.0 2.9e-22 79.5 0.0 1.9 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 KNE01965.1 - 8.5e-21 73.8 0.1 3e-20 72.0 0.0 2.0 2 0 0 2 2 2 1 Wyosine base formation Flavodoxin_1 PF00258.20 KNE01965.1 - 3e-12 46.7 0.0 1.7e-11 44.2 0.0 2.3 2 1 0 2 2 2 1 Flavodoxin Glycos_transf_1 PF00534.15 KNE01966.1 - 1.3e-26 92.9 0.4 8.4e-14 51.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KNE01966.1 - 2.3e-06 27.4 0.0 1.3e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_20 PF00982.16 KNE01966.1 - 0.00016 20.2 0.0 0.00024 19.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.1 KNE01966.1 - 0.00032 20.8 0.0 0.0012 18.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KNE01966.1 - 0.0085 16.2 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain DUF1992 PF09350.5 KNE01967.1 - 1.6e-14 53.4 0.3 1.5e-13 50.3 0.1 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1992) UPF0016 PF01169.14 KNE01968.1 - 2.2e-36 123.8 28.8 1.3e-19 70.1 6.0 2.8 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 Med8 PF10232.4 KNE01969.1 - 1.6e-41 142.2 7.4 2.7e-41 141.5 5.1 1.4 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 DUF4518 PF15008.1 KNE01969.1 - 0.023 13.7 0.1 0.036 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Allexi_40kDa PF05549.6 KNE01969.1 - 1.5 8.0 5.4 0.48 9.6 0.5 2.1 2 1 1 3 3 3 0 Allexivirus 40kDa protein IncA PF04156.9 KNE01969.1 - 8.1 5.9 9.9 16 5.0 0.4 2.3 2 1 0 2 2 2 0 IncA protein NpwBP PF12622.2 KNE01970.1 - 8.7e-08 32.5 0.5 8.7e-08 32.5 0.3 3.0 1 1 1 2 2 2 1 mRNA biogenesis factor Mito_carr PF00153.22 KNE01971.1 - 1e-78 259.1 0.7 2.5e-28 97.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3535 PF12054.3 KNE01972.1 - 2.1e-135 451.7 2.1 3.7e-134 447.6 0.6 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 KNE01972.1 - 2e-76 256.6 0.0 3.3e-76 255.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KNE01972.1 - 3.3e-14 52.4 0.0 7e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 KNE01972.1 - 2.5e-13 48.8 6.5 3.1 8.1 0.0 9.8 8 1 1 9 9 9 3 HEAT repeat Vac14_Fab1_bd PF12755.2 KNE01972.1 - 2.9e-07 30.7 0.0 0.021 15.2 0.0 4.3 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KNE01972.1 - 0.00011 22.5 7.9 13 6.4 0.0 8.7 9 0 0 9 9 9 1 HEAT-like repeat Cnd1 PF12717.2 KNE01972.1 - 0.00035 20.4 2.4 1.2 8.9 0.1 4.5 6 0 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 DUF4111 PF13427.1 KNE01972.1 - 0.055 13.3 0.6 0.34 10.7 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4111) DUF1014 PF06244.7 KNE01974.1 - 1.5e-29 102.6 16.0 1.1e-28 99.8 11.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) UDG PF03167.14 KNE01975.1 - 0.1 12.0 0.1 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily HMGL-like PF00682.14 KNE01976.1 - 8.4e-75 251.4 0.4 1.2e-74 251.0 0.3 1.2 1 0 0 1 1 1 1 HMGL-like Ribosomal_60s PF00428.14 KNE01976.1 - 0.00081 19.7 1.8 0.0019 18.5 1.2 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein ADP_PFK_GK PF04587.10 KNE01976.1 - 0.008 14.4 0.0 0.012 13.9 0.0 1.2 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region Mur_ligase_M PF08245.7 KNE01978.1 - 2.8e-05 24.2 0.0 0.00022 21.3 0.0 2.4 1 1 0 1 1 1 1 Mur ligase middle domain DUF592 PF04574.8 KNE01978.1 - 0.093 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF592) PCI PF01399.22 KNE01979.1 - 0.0004 20.6 0.8 0.0014 18.9 0.1 2.4 2 1 0 2 2 2 1 PCI domain THP2 PF09432.5 KNE01979.1 - 0.069 13.0 3.9 0.084 12.7 0.3 2.7 2 1 1 3 3 3 0 Tho complex subunit THP2 Pkinase PF00069.20 KNE01980.1 - 7.5e-68 228.4 0.1 1.3e-67 227.6 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE01980.1 - 8.4e-38 129.9 0.0 1.5e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNE01980.1 - 0.00016 20.7 0.0 0.0005 19.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KNE01980.1 - 0.022 13.8 0.1 0.15 11.1 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SUV3_C PF12513.3 KNE01981.1 - 2e-15 55.9 0.7 5.2e-15 54.6 0.3 1.9 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 KNE01981.1 - 2.3e-13 49.7 0.0 5.2e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_4 PF13871.1 KNE01981.1 - 0.035 13.5 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Helicase_C-like AAA_17 PF13207.1 KNE01982.1 - 4.5e-11 43.6 0.0 5.9e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KNE01982.1 - 1.5e-10 41.1 0.0 1.7e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KNE01982.1 - 1.9e-10 41.1 0.0 3.6e-10 40.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 KNE01982.1 - 8.3e-09 35.4 0.0 1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_19 PF13245.1 KNE01982.1 - 6.9e-05 22.5 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain APS_kinase PF01583.15 KNE01982.1 - 0.00018 21.1 0.0 0.00024 20.7 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.24 KNE01982.1 - 0.00048 20.3 0.1 0.0008 19.6 0.1 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KNE01982.1 - 0.00063 18.7 0.0 0.065 12.1 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 KNE01982.1 - 0.0009 19.3 0.0 0.0018 18.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KNE01982.1 - 0.0022 17.9 0.1 0.0036 17.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KNE01982.1 - 0.0027 17.3 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 KNE01982.1 - 0.0056 16.6 0.0 0.0098 15.8 0.0 1.4 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_5 PF07728.9 KNE01982.1 - 0.0076 15.9 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KNE01982.1 - 0.0098 14.9 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.12 KNE01982.1 - 0.015 14.6 0.0 0.55 9.5 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase ABC_tran PF00005.22 KNE01982.1 - 0.019 15.2 0.1 0.038 14.2 0.0 1.5 1 1 1 2 2 1 0 ABC transporter ADK PF00406.17 KNE01982.1 - 0.025 14.4 0.0 0.061 13.2 0.0 1.6 2 0 0 2 2 2 0 Adenylate kinase MobB PF03205.9 KNE01982.1 - 0.025 14.2 0.1 0.091 12.4 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.13 KNE01982.1 - 0.033 13.7 0.0 0.3 10.6 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family PhoH PF02562.11 KNE01982.1 - 0.04 13.1 0.1 0.071 12.3 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.1 KNE01982.1 - 0.041 13.7 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KNE01982.1 - 0.051 12.5 0.0 0.057 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.7 KNE01982.1 - 0.051 12.6 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus SRP54 PF00448.17 KNE01982.1 - 0.062 12.7 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain tRNA_lig_kinase PF08303.6 KNE01982.1 - 0.064 13.1 0.0 0.43 10.4 0.0 2.0 2 0 0 2 2 2 0 tRNA ligase kinase domain AAA_16 PF13191.1 KNE01982.1 - 0.073 13.0 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 KNE01982.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 KNE01982.1 - 0.13 11.8 0.1 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain CoaE PF01121.15 KNE01982.1 - 0.15 11.4 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase adh_short PF00106.20 KNE01984.1 - 2.1e-07 31.0 1.1 0.00043 20.2 0.0 2.6 3 0 0 3 3 3 2 short chain dehydrogenase Thiolase_N PF00108.18 KNE01985.1 - 2.4e-102 341.4 1.8 3.4e-102 340.9 1.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KNE01985.1 - 1.4e-45 153.6 1.3 6.2e-45 151.6 0.3 2.4 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KNE01985.1 - 1.7e-05 24.4 0.8 4.1e-05 23.1 0.6 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KNE01985.1 - 0.12 12.0 3.4 0.45 10.2 0.1 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FLILHELTA PF10306.4 KNE01986.1 - 2.5e-28 97.9 0.3 4.3e-28 97.1 0.2 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 KNE01986.1 - 0.065 13.5 0.4 0.14 12.5 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) Pkinase PF00069.20 KNE01987.1 - 1.6e-62 211.0 0.0 1.9e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE01987.1 - 2.4e-23 82.5 0.0 3.3e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNE01987.1 - 3.7e-05 22.8 0.0 9.8e-05 21.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KNE01987.1 - 0.0004 20.1 0.0 0.0016 18.2 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNE01987.1 - 0.01 15.4 0.2 0.021 14.3 0.1 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase DUF2262 PF10020.4 KNE01988.1 - 2.8 8.1 11.7 1.8 8.7 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2262) AA_permease PF00324.16 KNE01991.1 - 1.8e-112 376.1 42.0 2.1e-112 375.9 29.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KNE01991.1 - 1.3e-30 106.3 44.0 1.7e-30 105.9 30.5 1.0 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 KNE01992.1 - 4.8e-32 111.1 0.0 7.4e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE01992.1 - 3.1e-19 69.0 0.0 4e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNE01992.1 - 0.00044 19.2 0.0 0.0028 16.6 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KNE01993.1 - 3e-60 203.5 0.0 9.5e-59 198.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE01993.1 - 1e-29 103.3 1.0 2.1e-27 95.8 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KNE01993.1 - 0.014 14.3 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Wzt_C PF14524.1 KNE01993.1 - 0.096 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Wzt C-terminal domain FA_hydroxylase PF04116.8 KNE01994.1 - 1.8e-12 47.6 19.4 1.8e-12 47.6 13.4 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Porphobil_deam PF01379.15 KNE01995.1 - 1.2e-84 282.5 0.0 1.6e-84 282.1 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 KNE01995.1 - 2.4e-20 72.3 0.3 4.4e-20 71.5 0.2 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Myb_DNA-binding PF00249.26 KNE01995.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain SusD-like PF12741.2 KNE01995.1 - 0.14 10.7 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Susd and RagB outer membrane lipoprotein ERCC4 PF02732.10 KNE01999.1 - 2e-25 89.1 0.0 2.1e-24 85.8 0.0 2.6 1 1 1 2 2 2 1 ERCC4 domain MTHFR PF02219.12 KNE02001.1 - 1.5e-102 342.5 0.0 4.6e-102 340.9 0.0 1.8 3 0 0 3 3 3 1 Methylenetetrahydrofolate reductase ATG27 PF09451.5 KNE02002.1 - 5.5e-50 170.0 0.0 6.8e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 KNE02002.1 - 0.03 14.0 0.1 0.057 13.1 0.1 1.4 1 0 0 1 1 1 0 Cation-independent mannose-6-phosphate receptor repeat ATG16 PF08614.6 KNE02003.1 - 0.014 15.2 2.9 0.018 14.8 2.0 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.7 KNE02003.1 - 0.023 14.5 0.6 0.034 13.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 KNE02003.1 - 0.027 14.3 3.8 0.042 13.6 2.6 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Striatin PF08232.7 KNE02003.1 - 0.037 14.3 4.4 0.084 13.1 3.1 1.5 1 1 0 1 1 1 0 Striatin family DMPK_coil PF08826.5 KNE02003.1 - 0.042 13.7 1.6 0.081 12.8 1.1 1.4 1 0 0 1 1 1 0 DMPK coiled coil domain like CENP-K PF11802.3 KNE02003.1 - 0.048 12.9 1.8 0.065 12.4 1.3 1.1 1 0 0 1 1 1 0 Centromere-associated protein K Acyl-CoA_dh_2 PF08028.6 KNE02003.1 - 0.065 13.4 1.7 0.094 12.9 1.2 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain p450 PF00067.17 KNE02003.1 - 0.1 11.0 0.2 0.12 10.8 0.2 1.0 1 0 0 1 1 1 0 Cytochrome P450 IncA PF04156.9 KNE02003.1 - 0.18 11.4 6.1 0.31 10.5 4.2 1.6 1 1 0 1 1 1 0 IncA protein FlgN PF05130.7 KNE02003.1 - 0.22 11.7 5.8 0.17 12.1 3.0 1.5 1 1 0 1 1 1 0 FlgN protein Synaptobrevin PF00957.16 KNE02003.1 - 0.31 10.6 3.1 5.4 6.6 0.3 2.2 1 1 1 2 2 2 0 Synaptobrevin DivIC PF04977.10 KNE02003.1 - 1.7 8.1 5.4 1.7 8.1 1.2 2.1 2 0 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 KNE02003.1 - 2.5 8.4 4.4 1.2 9.4 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 KNE02003.1 - 3.4 7.2 7.1 0.7 9.5 2.1 1.7 1 1 1 2 2 2 0 Mnd1 family PAXNEB PF05625.6 KNE02004.1 - 2.7e-103 345.6 0.0 3.4e-103 345.2 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein Serinc PF03348.10 KNE02005.1 - 5.2e-157 522.9 12.7 5.9e-157 522.7 8.8 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Mpv17_PMP22 PF04117.7 KNE02005.1 - 0.00023 20.7 5.2 0.0014 18.2 3.6 2.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family ATP-synt_G PF04718.10 KNE02006.1 - 2.7e-29 101.8 0.5 3.2e-29 101.6 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit DEAD PF00270.24 KNE02007.1 - 4.2e-40 136.9 0.2 1.8e-39 134.9 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNE02007.1 - 2.8e-25 87.9 0.1 8.2e-25 86.4 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNE02007.1 - 0.00011 22.0 0.0 0.00011 22.0 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Sof1 PF04158.9 KNE02007.1 - 1.5 8.9 12.5 0.034 14.1 3.3 2.2 2 0 0 2 2 2 0 Sof1-like domain Ribonucleas_3_3 PF14622.1 KNE02008.1 - 1.3e-25 89.8 1.0 2e-25 89.1 0.7 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KNE02008.1 - 0.016 15.6 0.1 0.042 14.2 0.1 1.6 1 1 0 1 1 1 0 Ribonuclease III domain TfoX_C PF04994.8 KNE02008.1 - 0.022 14.6 0.2 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 TfoX C-terminal domain CRC_subunit PF08624.5 KNE02008.1 - 0.037 13.9 0.0 0.22 11.4 0.0 2.2 1 1 0 1 1 1 0 Chromatin remodelling complex Rsc7/Swp82 subunit Mito_carr PF00153.22 KNE02011.1 - 5.5e-51 170.2 7.5 3.6e-17 61.8 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Complex1_49kDa PF00346.14 KNE02012.1 - 0.066 12.1 0.1 0.12 11.3 0.0 1.5 1 1 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit UPF0223 PF05256.7 KNE02012.1 - 0.076 13.1 0.1 0.27 11.3 0.1 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0223) KxDL PF10241.4 KNE02012.1 - 0.67 9.8 3.0 0.29 11.0 0.3 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF1098 PF06497.6 KNE02013.1 - 0.11 12.5 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1098) BHD_1 PF10403.4 KNE02019.1 - 0.088 12.3 0.0 0.25 10.8 0.0 1.7 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 Mito_carr PF00153.22 KNE02020.1 - 3.8e-55 183.5 2.6 1e-20 73.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S19 PF00203.16 KNE02021.1 - 3e-30 103.6 0.1 3.4e-30 103.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_60s PF00428.14 KNE02022.1 - 1.6e-27 95.7 13.9 1.8e-27 95.5 9.7 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein ISG65-75 PF11727.3 KNE02022.1 - 0.076 12.0 0.8 0.09 11.8 0.5 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein FTA4 PF13093.1 KNE02023.1 - 1.2e-26 93.4 25.7 1e-25 90.4 17.8 2.0 1 1 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 SseC PF04888.7 KNE02023.1 - 0.054 12.8 2.1 0.12 11.6 1.5 1.6 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family YpjP PF14005.1 KNE02023.1 - 0.37 10.5 5.7 0.23 11.2 1.1 2.3 2 0 0 2 2 2 0 YpjP-like protein CorA PF01544.13 KNE02023.1 - 2.2 7.2 10.0 0.45 9.5 0.7 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF221 PF02714.10 KNE02025.1 - 8.9e-97 323.8 24.4 8.9e-97 323.8 16.9 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KNE02025.1 - 9.6e-41 138.9 0.4 9.6e-41 138.9 0.3 3.2 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KNE02025.1 - 1.2e-13 51.4 0.0 5.9e-13 49.1 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) Arv1 PF04161.8 KNE02026.1 - 8.6e-59 198.9 4.7 8.6e-59 198.9 3.3 1.4 2 0 0 2 2 2 1 Arv1-like family Phage_Coat_Gp8 PF05371.7 KNE02026.1 - 0.33 10.5 2.0 0.49 9.9 0.3 2.1 2 0 0 2 2 2 0 Phage major coat protein, Gp8 zf-CCCH PF00642.19 KNE02027.1 - 8.9e-08 31.6 2.5 1.7e-07 30.7 1.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nucleoporin_FG PF13634.1 KNE02027.1 - 0.0018 18.4 48.4 0.0018 18.4 33.5 7.0 1 1 4 5 5 5 1 Nucleoporin FG repeat region zf-CCCH_2 PF14608.1 KNE02027.1 - 0.68 10.0 2.6 1.6 8.8 1.8 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Topoisom_bac PF01131.15 KNE02028.1 - 1.7e-94 316.9 0.0 2e-94 316.6 0.0 1.0 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 KNE02028.1 - 6.3e-18 64.5 0.0 1.3e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Toprim domain SET PF00856.23 KNE02029.1 - 1.1e-13 51.7 0.0 2.1e-13 50.8 0.0 1.5 1 1 0 1 1 1 1 SET domain ApbA_C PF08546.6 KNE02030.1 - 2.7e-33 114.6 0.1 4.2e-33 113.9 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KNE02030.1 - 6.9e-30 103.4 0.0 1e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TfuA PF07812.7 KNE02030.1 - 0.035 13.5 0.0 0.071 12.5 0.0 1.6 1 0 0 1 1 1 0 TfuA-like protein CoaE PF01121.15 KNE02031.1 - 2.7e-54 183.2 0.1 3.3e-54 183.0 0.1 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 KNE02031.1 - 3.7e-08 34.2 0.1 7.5e-08 33.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KNE02031.1 - 0.00022 21.5 0.8 0.0018 18.5 0.5 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KNE02031.1 - 0.00034 20.4 0.0 0.0038 17.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KNE02031.1 - 0.01 15.7 0.1 0.026 14.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.1 KNE02031.1 - 0.018 14.9 0.3 0.11 12.4 0.2 1.9 1 1 0 1 1 1 0 Cytidylate kinase-like family SKI PF01202.17 KNE02031.1 - 0.056 13.3 0.1 0.97 9.2 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase PI3_PI4_kinase PF00454.22 KNE02032.1 - 3.1e-43 147.9 0.0 6.1e-43 146.9 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KNE02032.1 - 2.3e-34 118.1 7.9 5.8e-21 74.5 0.1 3.9 3 1 0 3 3 3 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.19 KNE02032.1 - 1.7e-18 66.7 0.0 3.6e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 His_Phos_1 PF00300.17 KNE02033.1 - 2.7e-08 34.0 0.0 9.9e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF2025 PF09634.5 KNE02033.1 - 0.011 15.4 0.1 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2025) dCMP_cyt_deam_1 PF00383.17 KNE02034.1 - 0.018 14.6 0.1 0.023 14.3 0.1 1.2 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 KNE02034.1 - 0.027 13.8 0.1 0.029 13.7 0.1 1.1 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases Peptidase_M24 PF00557.19 KNE02035.1 - 2.1e-45 154.8 0.0 2.7e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 KNE02035.1 - 0.038 13.8 3.9 0.1 12.5 2.7 1.7 1 0 0 1 1 1 0 MYND finger Phosphodiest PF01663.17 KNE02036.1 - 1.3e-12 47.7 0.4 1.5e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KNE02036.1 - 6.4e-06 25.7 0.3 1.1e-05 24.9 0.2 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 KNE02036.1 - 0.018 14.2 0.0 0.036 13.2 0.0 1.5 1 0 0 1 1 1 0 Sulfatase DUF229 PF02995.12 KNE02036.1 - 0.057 11.8 0.1 0.084 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) HisG_C PF08029.6 KNE02036.1 - 0.14 12.0 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 HisG, C-terminal domain zf-C2H2_2 PF12756.2 KNE02037.1 - 1.1e-32 112.1 1.9 2.3e-32 111.1 1.3 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) DNA_pol_A_exo1 PF01612.15 KNE02038.1 - 2.7e-42 144.2 0.0 5.1e-42 143.3 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 KNE02038.1 - 2.7e-08 34.0 0.2 2.7e-08 34.0 0.1 2.6 3 0 0 3 3 3 1 PMC2NT (NUC016) domain HRDC PF00570.18 KNE02038.1 - 1.7e-06 27.6 0.0 4.4e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 HRDC domain CheR PF01739.13 KNE02039.1 - 0.042 13.1 0.2 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_23 PF13489.1 KNE02039.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain His_biosynth PF00977.16 KNE02040.1 - 4.5e-43 147.1 0.1 2.6e-42 144.6 0.1 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 KNE02040.1 - 3.1e-25 88.7 0.0 7.6e-25 87.4 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 KNE02040.1 - 1.4e-10 40.9 0.0 2.8e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 KNE02040.1 - 8.9e-07 28.7 0.1 0.0028 17.3 0.0 2.4 2 0 0 2 2 2 2 SNO glutamine amidotransferase family ThiG PF05690.9 KNE02040.1 - 0.0047 16.0 0.1 0.0089 15.1 0.0 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG BPL_N PF09825.4 KNE02040.1 - 0.018 13.8 0.0 0.044 12.5 0.0 1.6 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal NMO PF03060.10 KNE02040.1 - 0.094 11.8 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Bystin PF05291.6 KNE02041.1 - 1.3e-118 395.3 0.0 1.7e-118 394.9 0.0 1.1 1 0 0 1 1 1 1 Bystin MatE PF01554.13 KNE02042.1 - 2.5e-55 186.5 30.5 3.2e-29 101.6 8.6 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 KNE02042.1 - 2.8e-05 23.9 7.4 2.8e-05 23.9 5.1 3.6 4 0 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain MVIN PF03023.9 KNE02042.1 - 0.00016 20.2 10.1 0.00016 20.2 7.0 2.4 2 1 0 3 3 3 1 MviN-like protein Rcd1 PF04078.8 KNE02043.1 - 9.8e-121 401.5 1.3 1.1e-119 398.1 0.9 1.9 1 1 0 1 1 1 1 Cell differentiation family, Rcd1-like HMA PF00403.21 KNE02044.1 - 1.6e-09 37.7 0.1 3.4e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.15 KNE02044.1 - 0.00029 21.0 0.0 0.0018 18.4 0.0 2.0 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SOG2 PF10428.4 KNE02045.1 - 5.6e-56 190.0 20.1 3e-30 105.2 4.3 3.0 1 1 2 3 3 3 2 RAM signalling pathway protein LRR_8 PF13855.1 KNE02045.1 - 8.3e-21 73.5 12.7 7.1e-11 41.6 0.1 4.3 3 1 2 5 5 5 3 Leucine rich repeat LRR_4 PF12799.2 KNE02045.1 - 5.2e-18 64.2 7.0 1.1e-07 31.2 0.1 3.9 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KNE02045.1 - 2.3e-10 39.0 7.4 0.037 14.0 0.1 6.2 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 KNE02045.1 - 5e-09 34.9 0.7 0.76 10.2 0.0 6.1 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 KNE02045.1 - 0.00063 19.5 5.7 1.1 9.5 0.0 5.4 5 0 0 5 5 5 1 Leucine Rich repeat TauD PF02668.11 KNE02046.1 - 3.3e-43 148.2 0.0 4.5e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 KNE02046.1 - 0.057 13.9 0.0 16 6.0 0.0 2.4 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily CN_hydrolase PF00795.17 KNE02047.1 - 5.5e-26 91.0 0.0 9.5e-26 90.2 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 KNE02047.1 - 2e-24 85.8 0.0 7.2e-24 84.0 0.0 1.7 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 KNE02047.1 - 0.063 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase Abhydrolase_6 PF12697.2 KNE02048.1 - 3.5e-20 72.8 0.0 5.1e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNE02048.1 - 4.2e-10 39.5 0.0 1.2e-09 38.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNE02048.1 - 5.2e-08 32.7 0.0 7.1e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KNE02048.1 - 0.00017 21.3 0.0 0.00037 20.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DUF676 PF05057.9 KNE02048.1 - 0.047 12.9 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.20 KNE02048.1 - 0.047 13.2 0.0 0.096 12.3 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 KNE02048.1 - 0.13 11.7 0.0 0.96 8.9 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein TFIIE_alpha PF02002.12 KNE02048.1 - 0.14 11.6 0.6 0.37 10.3 0.0 1.9 2 0 0 2 2 2 0 TFIIE alpha subunit dCMP_cyt_deam_1 PF00383.17 KNE02049.1 - 1.5e-18 66.3 0.0 2.3e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KNE02049.1 - 4.7e-05 23.2 0.6 0.00013 21.8 0.4 1.7 1 1 0 1 1 1 1 Bd3614-like deaminase DPBB_1 PF03330.13 KNE02050.1 - 5.6e-11 42.2 0.0 1.4e-10 40.9 0.0 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KNE02050.1 - 0.018 14.6 0.0 0.04 13.5 0.0 1.6 1 0 0 1 1 1 0 Barwin family Cerato-platanin PF07249.7 KNE02050.1 - 0.023 14.7 0.2 0.065 13.2 0.0 1.9 3 0 0 3 3 3 0 Cerato-platanin Ssl1 PF04056.9 KNE02051.1 - 6.3e-62 208.5 0.1 9.5e-62 208.0 0.1 1.3 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 KNE02051.1 - 6.2e-22 77.3 11.2 6.2e-22 77.3 7.8 2.6 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 KNE02051.1 - 7.4e-08 32.6 0.0 1.3e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KNE02051.1 - 0.00055 19.6 0.0 0.00086 19.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain DZR PF12773.2 KNE02051.1 - 3 7.7 21.0 1.2 8.9 2.2 3.4 2 1 0 2 2 2 0 Double zinc ribbon zf-HIT PF04438.11 KNE02051.1 - 5.8 6.6 25.1 0.089 12.4 0.4 3.9 4 0 0 4 4 4 0 HIT zinc finger Spt5-NGN PF03439.8 KNE02052.1 - 6.9e-24 83.4 0.0 1.9e-23 81.9 0.0 1.8 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 KNE02052.1 - 4.1e-22 78.5 16.2 4.1e-22 78.5 11.2 3.2 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 KNE02052.1 - 1.5e-10 40.3 23.4 0.0004 19.9 0.7 5.9 6 0 0 6 6 6 4 KOW motif NusG PF02357.14 KNE02052.1 - 0.0021 18.2 0.1 0.1 12.8 0.0 3.1 3 0 0 3 3 3 1 Transcription termination factor nusG Pribosyltran PF00156.22 KNE02054.1 - 1.6e-19 69.8 0.0 2.1e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KNE02054.1 - 0.00051 19.3 0.0 0.00066 18.9 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_3 PF15610.1 KNE02054.1 - 0.022 13.6 0.0 0.03 13.2 0.0 1.1 1 0 0 1 1 1 0 PRTase ComF-like Dynein_light PF01221.13 KNE02055.1 - 1.9e-30 104.7 0.1 2.1e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3646 PF12362.3 KNE02055.1 - 0.022 14.6 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal Med13_C PF06333.7 KNE02056.1 - 6.5e-98 328.0 0.4 6.5e-98 328.0 0.3 2.5 2 1 0 2 2 2 1 Mediator complex subunit 13 C-terminal GAS PF13851.1 KNE02057.1 - 0.00029 20.0 9.5 0.00051 19.2 4.9 2.2 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Arfaptin PF06456.8 KNE02057.1 - 0.016 14.5 1.2 0.016 14.5 0.9 2.9 3 0 0 3 3 3 0 Arfaptin-like domain IncA PF04156.9 KNE02057.1 - 7.8 6.0 8.7 3.6 7.1 4.1 2.0 2 0 0 2 2 2 0 IncA protein Cyclin_N PF00134.18 KNE02058.1 - 1.2e-45 154.1 0.3 5.2e-44 148.8 0.4 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KNE02058.1 - 1e-32 112.5 0.0 4e-32 110.6 0.0 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain BRCT PF00533.21 KNE02059.1 - 1.7e-25 88.9 1.6 4.7e-06 26.6 0.0 5.9 6 0 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KNE02059.1 - 8.9e-23 79.9 0.0 3e-12 46.2 0.0 4.6 4 0 0 4 4 4 4 twin BRCT domain Seryl_tRNA_N PF02403.17 KNE02059.1 - 0.028 14.4 5.5 0.064 13.2 3.8 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ENTH PF01417.15 KNE02060.1 - 6.6e-43 145.5 0.1 1.3e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 ENTH domain PAT1 PF09770.4 KNE02060.1 - 0.00012 20.4 33.8 0.00016 20.0 23.5 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 UIM PF02809.15 KNE02060.1 - 0.00069 18.9 13.9 0.025 14.1 0.3 3.1 3 0 0 3 3 3 2 Ubiquitin interaction motif DUF1510 PF07423.6 KNE02062.1 - 0.015 14.7 8.6 0.024 14.0 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Zip PF02535.17 KNE02062.1 - 0.16 10.9 1.0 0.23 10.4 0.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Glyco_hydro_76 PF03663.9 KNE02063.1 - 4.8e-152 506.6 22.4 6.1e-152 506.3 15.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 PX PF00787.19 KNE02064.1 - 4.5e-15 55.4 0.4 4.5e-15 55.4 0.3 2.1 2 0 0 2 2 2 1 PX domain DUF2400 PF09674.5 KNE02064.1 - 0.01 15.5 1.9 0.012 15.3 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) Striatin PF08232.7 KNE02064.1 - 0.046 14.0 0.2 0.046 14.0 0.1 3.6 3 1 0 3 3 3 0 Striatin family RmuC PF02646.11 KNE02064.1 - 0.26 10.0 7.9 0.026 13.3 0.7 2.2 2 0 0 2 2 2 0 RmuC family Lung_7-TM_R PF06814.8 KNE02065.1 - 5.8e-57 192.8 17.1 1.1e-56 191.9 11.9 1.5 1 1 0 1 1 1 1 Lung seven transmembrane receptor NdhL PF10716.4 KNE02065.1 - 0.026 14.2 0.2 0.026 14.2 0.1 2.3 2 0 0 2 2 2 0 NADH dehydrogenase transmembrane subunit DUF1625 PF07787.7 KNE02065.1 - 0.2 10.8 6.1 0.28 10.4 3.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1625) PCI PF01399.22 KNE02066.1 - 9.1e-09 35.5 1.0 9.1e-09 35.5 0.7 2.3 2 0 0 2 2 2 1 PCI domain PX PF00787.19 KNE02067.1 - 3.1e-17 62.3 1.1 1.2e-16 60.4 0.4 2.3 1 1 1 2 2 2 1 PX domain Mannosyl_trans3 PF11051.3 KNE02069.1 - 1.7e-88 296.4 0.0 2.8e-88 295.7 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative LCM PF04072.9 KNE02070.1 - 1.4e-25 89.8 0.0 3.9e-25 88.4 0.0 1.7 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Clr5 PF14420.1 KNE02071.1 - 0.0079 16.0 3.0 0.011 15.6 2.1 1.2 1 0 0 1 1 1 1 Clr5 domain DUF3899 PF13038.1 KNE02071.1 - 0.18 11.9 1.2 0.2 11.8 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) BLVR PF06375.6 KNE02071.1 - 1.2 8.8 7.6 1.3 8.7 5.3 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Med19 PF10278.4 KNE02071.1 - 1.6 8.3 10.0 1.8 8.2 6.9 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Methyltransf_11 PF08241.7 KNE02074.1 - 3.6e-12 46.5 0.1 1.3e-11 44.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNE02074.1 - 1.4e-08 34.4 0.1 2.1e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNE02074.1 - 5.5e-08 32.6 0.0 9.2e-08 31.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNE02074.1 - 2.1e-06 28.1 0.1 3.9e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNE02074.1 - 5.6e-06 26.8 0.1 9.7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNE02074.1 - 0.001 19.3 0.0 0.0029 17.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 KNE02074.1 - 0.0011 18.4 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.6 KNE02074.1 - 0.064 11.9 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TAFII28 PF04719.9 KNE02076.1 - 6.6e-22 77.1 0.3 6.2e-20 70.7 0.1 2.4 1 1 1 2 2 2 2 hTAFII28-like protein conserved region MCM PF00493.18 KNE02076.1 - 0.019 13.8 1.1 0.024 13.4 0.8 1.2 1 0 0 1 1 1 0 MCM2/3/5 family DUF3419 PF11899.3 KNE02077.1 - 3.5e-143 476.9 0.0 4.8e-143 476.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_12 PF08242.7 KNE02077.1 - 4e-08 33.6 0.1 8.7e-06 26.1 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNE02077.1 - 1.2e-07 31.5 0.0 6.7e-06 25.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNE02077.1 - 3.5e-07 29.9 0.0 6.3e-06 25.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNE02077.1 - 1.1e-06 29.1 0.0 0.00081 19.9 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNE02077.1 - 0.00045 20.2 0.0 0.007 16.3 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNE02077.1 - 0.00062 20.2 0.0 0.0082 16.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNE02077.1 - 0.0014 18.9 0.0 0.0041 17.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KNE02077.1 - 0.0083 15.2 0.0 0.02 14.0 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.1 KNE02077.1 - 0.041 14.7 0.0 2.3 9.1 0.0 3.1 2 1 1 3 3 3 0 Methyltransferase domain CM_2 PF01817.16 KNE02078.1 - 7.3e-07 29.1 0.4 0.0091 16.0 0.0 3.4 2 1 1 3 3 3 2 Chorismate mutase type II TetR_C_8 PF14278.1 KNE02078.1 - 0.0049 17.2 0.2 4.7 7.6 0.0 2.9 3 0 0 3 3 3 2 Transcriptional regulator C-terminal region DnaJ PF00226.26 KNE02079.1 - 7.6e-13 47.9 1.8 1.5e-12 47.0 1.2 1.6 1 0 0 1 1 1 1 DnaJ domain UPF0240 PF06784.6 KNE02079.1 - 0.026 14.1 0.6 0.048 13.3 0.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) Amidohydro_1 PF01979.15 KNE02080.1 - 9.1e-11 41.9 0.3 3.9e-07 30.0 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KNE02080.1 - 3.8e-08 33.6 0.3 1.9e-05 24.8 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 KNE02080.1 - 1.2e-05 24.7 0.0 4.8e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 KNE02080.1 - 4.6e-05 23.1 0.0 0.00018 21.2 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase Glucosamine_iso PF01182.15 KNE02082.1 - 2.4e-18 66.5 0.0 4.6e-18 65.6 0.0 1.4 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hexokinase_1 PF00349.16 KNE02084.1 - 7e-22 77.7 0.2 1.4e-21 76.7 0.0 1.5 2 0 0 2 2 2 1 Hexokinase Hexokinase_2 PF03727.11 KNE02084.1 - 1.1e-18 67.3 0.8 7.3e-18 64.6 0.5 2.1 1 1 0 1 1 1 1 Hexokinase RHD3 PF05879.7 KNE02085.1 - 2.9e-253 842.1 13.4 3.6e-253 841.8 9.3 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 KNE02085.1 - 4.2e-08 32.5 0.1 7.9e-08 31.6 0.1 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_28 PF13521.1 KNE02085.1 - 7.9e-05 22.6 0.9 0.00056 19.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 KNE02085.1 - 8.4e-05 22.5 0.0 0.0003 20.7 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KNE02085.1 - 0.00016 21.5 0.0 0.00016 21.5 0.0 2.8 3 0 0 3 3 3 1 Dynamin family Miro PF08477.8 KNE02085.1 - 0.009 16.4 0.0 0.028 14.9 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 KNE02085.1 - 0.015 15.4 0.2 1.7 8.7 0.0 3.4 2 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.17 KNE02085.1 - 0.051 13.7 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 KNE02085.1 - 0.11 12.4 1.7 0.46 10.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain PBP1_TM PF14812.1 KNE02085.1 - 0.34 11.2 5.0 0.28 11.4 1.0 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GTP_EFTU PF00009.22 KNE02086.1 - 3.5e-58 196.1 0.1 6.4e-58 195.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KNE02086.1 - 1.2e-22 79.4 0.0 2.4e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KNE02086.1 - 1.5e-15 56.7 0.0 2.5e-14 52.9 0.0 2.4 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KNE02086.1 - 2.6e-11 43.4 0.2 6.6e-11 42.1 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KNE02086.1 - 0.0017 18.2 0.0 0.0051 16.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF2213 PF09979.4 KNE02086.1 - 0.14 11.7 0.3 3.3 7.3 0.0 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2213) UAA PF08449.6 KNE02087.1 - 3.7e-67 226.4 19.5 4.4e-67 226.1 13.5 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KNE02087.1 - 2e-08 34.0 9.7 2e-08 34.0 6.7 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family Borrelia_P13 PF05628.7 KNE02087.1 - 0.012 15.4 1.7 0.23 11.2 0.3 2.3 2 0 0 2 2 2 0 Borrelia membrane protein P13 Na_Pi_cotrans PF02690.10 KNE02087.1 - 0.012 15.2 4.9 0.012 15.2 3.4 3.0 2 2 1 3 3 3 0 Na+/Pi-cotransporter DUF3754 PF12576.3 KNE02087.1 - 5.4 6.6 6.3 0.5 9.9 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3754) ABC_membrane PF00664.18 KNE02088.1 - 4.3e-50 170.6 41.6 6.6e-30 104.4 14.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KNE02088.1 - 4.3e-45 153.3 2.2 4.1e-27 95.1 0.0 3.4 3 1 0 3 3 2 2 ABC transporter SMC_N PF02463.14 KNE02088.1 - 5e-10 38.9 6.5 0.00047 19.4 0.8 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KNE02088.1 - 1e-07 32.2 8.9 0.00034 20.6 0.0 5.2 3 2 0 4 4 4 1 AAA domain AAA_29 PF13555.1 KNE02088.1 - 1.8e-07 30.5 0.2 0.0014 18.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KNE02088.1 - 0.00015 21.3 4.4 0.34 10.3 0.1 3.7 3 1 0 4 4 4 2 FtsK/SpoIIIE family DUF258 PF03193.11 KNE02088.1 - 0.00023 20.4 0.8 0.15 11.2 0.2 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KNE02088.1 - 0.00044 21.0 8.2 0.29 11.9 0.0 4.1 4 0 0 4 4 4 2 AAA domain MMR_HSR1 PF01926.18 KNE02088.1 - 0.00047 20.0 0.1 0.49 10.3 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 KNE02088.1 - 0.0028 17.6 1.2 0.22 11.4 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain Zeta_toxin PF06414.7 KNE02088.1 - 0.0052 15.9 0.5 0.4 9.7 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin AAA_18 PF13238.1 KNE02088.1 - 0.0096 16.2 7.1 0.84 9.9 0.0 3.9 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 KNE02088.1 - 0.0097 16.4 7.9 0.96 9.9 0.1 3.4 3 0 0 3 3 3 2 Miro-like protein T2SE PF00437.15 KNE02088.1 - 0.018 13.9 0.0 2.8 6.7 0.1 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_25 PF13481.1 KNE02088.1 - 0.019 14.3 0.3 2.7 7.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 KNE02088.1 - 0.039 14.2 0.1 0.039 14.2 0.1 4.1 3 1 1 4 4 3 0 AAA domain APS_kinase PF01583.15 KNE02088.1 - 0.041 13.5 1.1 6.6 6.3 0.1 3.7 4 0 0 4 4 3 0 Adenylylsulphate kinase AAA_22 PF13401.1 KNE02088.1 - 0.1 12.7 5.4 12 6.0 0.1 4.1 3 1 0 3 3 2 0 AAA domain AAA_30 PF13604.1 KNE02088.1 - 0.18 11.3 2.5 3.7 7.0 0.0 3.1 4 0 0 4 4 4 0 AAA domain PTR2 PF00854.16 KNE02092.1 - 9.9e-50 169.3 16.7 1.2e-49 169.0 11.6 1.1 1 0 0 1 1 1 1 POT family Pkinase PF00069.20 KNE02093.1 - 8.8e-76 254.4 0.0 1.3e-75 253.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE02093.1 - 1.5e-36 125.7 0.0 2.3e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KNE02093.1 - 4.8e-29 100.2 1.7 1.9e-13 50.3 0.1 3.0 2 0 0 2 2 2 2 FHA domain Kinase-like PF14531.1 KNE02093.1 - 1.5e-08 34.0 0.0 5.2e-08 32.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KNE02093.1 - 0.00019 20.5 0.0 0.00035 19.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KNE02093.1 - 0.00022 21.0 0.0 0.031 13.9 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 KNE02093.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kinesin PF00225.18 KNE02094.1 - 6e-83 278.3 0.1 8.9e-83 277.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF2366 PF10171.4 KNE02094.1 - 0.043 13.3 0.2 0.1 12.0 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2366) RRM_5 PF13893.1 KNE02096.1 - 0.00097 18.9 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TruD PF01142.13 KNE02097.1 - 8.8e-63 212.2 6.2 2.6e-60 204.1 0.1 4.4 3 2 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) Rhodanese PF00581.15 KNE02098.1 - 2e-17 63.5 0.0 3.5e-09 36.9 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain WD40 PF00400.27 KNE02099.1 - 8.6e-60 196.6 19.6 7e-13 47.9 0.6 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KNE02099.1 - 5.5e-06 24.7 1.5 0.001 17.3 0.0 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KNE02099.1 - 0.0013 17.5 0.0 0.07 11.8 0.0 2.3 2 0 0 2 2 2 2 Nup133 N terminal like DUF572 PF04502.8 KNE02099.1 - 0.3 10.2 0.1 0.46 9.6 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ist1 PF03398.9 KNE02101.1 - 3.4e-58 195.7 0.2 4.2e-58 195.3 0.2 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Pkinase PF00069.20 KNE02103.1 - 9.7e-58 195.3 1.2 6.7e-56 189.3 0.9 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE02103.1 - 3.7e-18 65.5 0.0 1.1e-17 64.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KNE02103.1 - 0.0047 16.6 0.1 0.016 14.9 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KNE02103.1 - 0.059 12.3 0.1 0.44 9.4 0.0 2.2 2 0 0 2 2 2 0 Kinase-like WD40 PF00400.27 KNE02105.1 - 4e-36 121.6 5.9 1.2e-07 31.3 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 KNE02105.1 - 4.1e-33 113.2 15.9 6.6e-33 112.5 11.0 1.3 1 0 0 1 1 1 1 Sof1-like domain BBS2_Mid PF14783.1 KNE02105.1 - 0.017 14.8 0.0 3 7.6 0.0 2.9 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region NIF PF03031.13 KNE02106.1 - 2.3e-50 170.3 0.2 3.3e-50 169.8 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KNE02106.1 - 0.0018 18.4 0.1 0.04 14.1 0.0 2.1 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Pyr_redox_2 PF07992.9 KNE02108.1 - 3.8e-41 141.2 1.0 7.3e-41 140.2 0.7 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KNE02108.1 - 8.1e-34 115.9 1.7 3.8e-33 113.8 0.1 2.5 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KNE02108.1 - 6.5e-17 61.7 7.2 6.3e-15 55.3 0.3 3.0 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KNE02108.1 - 2.8e-11 43.8 1.3 8.7e-09 35.7 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KNE02108.1 - 6.6e-08 32.0 0.0 1.2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KNE02108.1 - 8.7e-06 24.4 4.6 0.0043 15.5 0.3 3.3 3 1 1 4 4 4 2 HI0933-like protein GIDA PF01134.17 KNE02108.1 - 8.9e-05 21.5 10.4 0.00015 20.7 1.3 2.7 2 2 0 2 2 2 2 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.14 KNE02108.1 - 0.00027 20.1 1.9 0.13 11.4 0.0 3.2 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KNE02108.1 - 0.0004 19.9 1.9 0.055 13.0 0.1 2.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.1 KNE02108.1 - 0.00042 19.3 0.0 0.00076 18.4 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KNE02108.1 - 0.00052 19.0 1.6 0.00052 19.0 1.1 3.0 3 1 0 3 3 3 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KNE02108.1 - 0.002 17.7 7.7 0.011 15.4 0.1 2.6 3 0 0 3 3 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KNE02108.1 - 0.0021 16.9 2.3 0.0055 15.6 1.6 1.7 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 KNE02108.1 - 0.019 14.0 2.5 0.79 8.7 0.2 2.5 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.1 KNE02108.1 - 0.02 14.8 2.6 0.02 14.8 1.8 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KNE02108.1 - 0.035 13.2 1.4 0.085 11.9 0.1 2.2 3 0 0 3 3 3 0 Thi4 family DUF3888 PF13027.1 KNE02108.1 - 0.067 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3888) NAD_binding_7 PF13241.1 KNE02108.1 - 0.079 13.2 0.3 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 KNE02108.1 - 0.18 11.1 2.8 0.18 11.1 0.1 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.1 KNE02108.1 - 0.22 11.2 0.0 0.22 11.2 0.0 2.6 4 0 0 4 4 3 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 KNE02108.1 - 0.24 11.0 1.5 6.7 6.4 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Clp1 PF06807.9 KNE02110.1 - 2e-18 66.8 0.0 1.4e-17 64.0 0.0 2.2 2 1 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KNE02110.1 - 4e-07 29.8 0.1 3.6e-05 23.4 0.0 2.3 1 1 1 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KNE02110.1 - 0.00046 19.7 0.0 0.0008 18.9 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Miro PF08477.8 KNE02110.1 - 0.0045 17.4 0.0 0.012 16.1 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KNE02110.1 - 0.0075 15.5 0.3 0.14 11.3 0.0 2.7 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 KNE02110.1 - 0.021 14.8 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 KNE02110.1 - 0.027 13.9 0.1 0.7 9.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DAP3 PF10236.4 KNE02110.1 - 0.037 12.9 0.1 0.078 11.8 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ATP_bind_1 PF03029.12 KNE02110.1 - 0.074 12.5 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_35 PF14516.1 KNE02110.1 - 0.095 11.3 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain PTPA PF03095.10 KNE02111.1 - 5.7e-117 390.1 0.2 6.8e-117 389.9 0.2 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein LETM1 PF07766.8 KNE02112.1 - 3.3e-05 23.0 4.5 0.24 10.3 0.0 3.2 3 0 0 3 3 3 3 LETM1-like protein MOZ_SAS PF01853.13 KNE02113.1 - 1.3e-82 275.6 4.0 8.2e-77 256.7 0.5 2.5 3 0 0 3 3 3 2 MOZ/SAS family Tudor-knot PF11717.3 KNE02113.1 - 1.5e-20 72.6 0.4 4e-20 71.2 0.3 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF4325 PF14213.1 KNE02113.1 - 0.12 12.0 0.0 0.65 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4325) WD40 PF00400.27 KNE02114.1 - 9.3e-40 133.1 10.6 3.4e-07 29.8 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KNE02114.1 - 0.00095 18.0 0.1 2.7 6.6 0.0 3.9 1 1 1 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 KNE02114.1 - 0.0087 14.2 4.0 0.61 8.1 0.1 3.4 2 2 1 3 3 3 3 Nucleoporin Nup120/160 PI31_Prot_C PF08577.6 KNE02118.1 - 9.1e-18 64.6 8.3 9.1e-18 64.6 5.7 2.3 2 0 0 2 2 2 1 PI31 proteasome regulator UPF0193 PF05250.6 KNE02118.1 - 0.02 14.4 0.2 0.028 13.9 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) DUF3013 PF11217.3 KNE02118.1 - 0.023 14.4 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3013) MAM33 PF02330.11 KNE02118.1 - 0.034 13.8 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial glycoprotein Glucosamine_iso PF01182.15 KNE02120.1 - 1.2e-46 159.0 0.0 1.7e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF4432 PF14486.1 KNE02121.1 - 0.032 12.7 0.0 0.032 12.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) ABC_membrane PF00664.18 KNE02123.1 - 1.5e-54 185.2 42.1 3e-35 121.9 10.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KNE02123.1 - 6.5e-45 152.7 0.3 1.4e-28 99.9 0.0 3.3 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KNE02123.1 - 6e-11 42.8 6.3 1.8e-07 31.4 0.0 4.9 3 2 0 4 4 4 1 AAA domain SMC_N PF02463.14 KNE02123.1 - 6.6e-08 32.0 6.8 0.00068 18.9 0.4 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KNE02123.1 - 1e-05 24.9 1.2 0.041 13.3 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KNE02123.1 - 1.3e-05 25.6 6.4 0.11 12.8 0.6 3.9 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KNE02123.1 - 1.6e-05 25.6 0.3 0.33 11.7 0.0 3.5 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 KNE02123.1 - 0.00018 21.8 0.3 0.61 10.4 0.0 3.5 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 KNE02123.1 - 0.00071 18.7 0.0 0.37 9.8 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin Miro PF08477.8 KNE02123.1 - 0.00073 20.0 1.2 0.78 10.2 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 KNE02123.1 - 0.001 19.2 0.9 2.8 8.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 KNE02123.1 - 0.0013 17.9 3.2 1.2 8.3 0.2 3.2 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KNE02123.1 - 0.0022 18.0 0.1 0.061 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.12 KNE02123.1 - 0.0058 16.1 1.0 3.3 7.1 0.0 3.2 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 KNE02123.1 - 0.0069 16.3 5.5 0.36 10.8 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_30 PF13604.1 KNE02123.1 - 0.011 15.2 1.3 0.77 9.3 0.1 2.7 3 0 0 3 3 2 0 AAA domain cobW PF02492.14 KNE02123.1 - 0.015 14.7 1.3 0.061 12.7 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Vps51 PF08700.6 KNE02123.1 - 0.015 15.0 0.4 0.065 13.0 0.3 2.1 1 0 0 1 1 1 0 Vps51/Vps67 AAA_19 PF13245.1 KNE02123.1 - 0.026 14.2 0.1 0.08 12.6 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain Dynamin_N PF00350.18 KNE02123.1 - 0.04 13.7 2.9 1.3 8.8 0.5 2.6 2 0 0 2 2 2 0 Dynamin family AAA_14 PF13173.1 KNE02123.1 - 0.075 12.9 0.5 2.7 7.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain UPF0079 PF02367.12 KNE02123.1 - 0.098 12.2 0.6 0.28 10.7 0.1 2.0 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 KNE02123.1 - 0.1 11.4 1.6 0.19 10.5 0.1 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 KNE02123.1 - 0.11 11.8 0.7 3.4 7.0 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_15 PF13175.1 KNE02123.1 - 0.16 10.9 8.0 0.26 10.2 0.3 3.4 3 0 0 3 3 3 0 AAA ATPase domain Arch_ATPase PF01637.13 KNE02123.1 - 0.75 9.4 4.9 0.26 10.9 0.0 2.7 4 0 0 4 4 3 0 Archaeal ATPase UCH PF00443.24 KNE02124.1 - 1.1e-58 198.5 1.2 1.9e-58 197.7 0.9 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KNE02124.1 - 2.5e-27 96.0 0.8 2.5e-27 96.0 0.6 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KNE02124.1 - 2.7e-12 46.6 10.4 2.7e-12 46.6 7.2 2.5 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Viral_protease PF08715.5 KNE02124.1 - 0.0012 17.9 0.1 0.0029 16.7 0.0 1.6 1 0 0 1 1 1 1 Papain like viral protease Phosducin PF02114.11 KNE02126.1 - 5e-12 45.1 1.9 6.3e-12 44.7 1.3 1.2 1 0 0 1 1 1 1 Phosducin Dymeclin PF09742.4 KNE02126.1 - 0.002 16.3 0.2 0.0025 16.0 0.2 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Thioredoxin PF00085.15 KNE02126.1 - 0.086 12.5 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin PmbA_TldD PF01523.11 KNE02126.1 - 0.37 10.0 2.2 0.57 9.3 1.5 1.3 1 0 0 1 1 1 0 Putative modulator of DNA gyrase DUF866 PF05907.8 KNE02127.1 - 4.6e-44 149.7 1.3 5.1e-44 149.6 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Ribosomal_L44 PF00935.14 KNE02127.1 - 0.00082 19.3 1.2 0.78 9.7 0.1 2.2 2 0 0 2 2 2 2 Ribosomal protein L44 Mcm10 PF09332.6 KNE02127.1 - 0.005 16.2 1.1 0.0065 15.8 0.8 1.1 1 0 0 1 1 1 1 Mcm10 replication factor Lar_restr_allev PF14354.1 KNE02127.1 - 0.21 11.8 1.4 6.1 7.2 0.1 2.5 1 1 1 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 KNE02127.1 - 0.63 9.8 4.8 1.8 8.4 2.9 2.0 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Cytochrom_C PF00034.16 KNE02128.1 - 1.8e-09 38.3 0.0 2.6e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KNE02128.1 - 5e-07 29.7 1.9 5.5e-06 26.4 1.3 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 KNE02128.1 - 0.011 15.1 0.4 0.055 12.9 0.1 2.0 2 0 0 2 2 2 0 Cytochrome c-550 domain Cytochrom_C1 PF02167.10 KNE02128.1 - 0.021 14.5 0.0 0.025 14.2 0.0 1.3 1 1 0 1 1 1 0 Cytochrome C1 family MA3 PF02847.12 KNE02129.1 - 1.3e-14 53.9 0.5 3.7e-14 52.3 0.1 2.0 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.14 KNE02129.1 - 4.8e-12 45.7 0.5 1e-11 44.6 0.3 1.6 1 0 0 1 1 1 1 MIF4G domain PPR_2 PF13041.1 KNE02130.1 - 2.6e-10 40.0 0.0 6.1e-08 32.5 0.0 3.0 3 0 0 3 3 3 2 PPR repeat family tify PF06200.9 KNE02130.1 - 0.16 11.2 0.1 1.2 8.4 0.0 2.5 2 0 0 2 2 2 0 tify domain CTP_transf_2 PF01467.21 KNE02131.1 - 3.9e-07 30.2 0.0 1.5e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 Cytidylyltransferase USP7_C2 PF14533.1 KNE02132.1 - 9.4e-55 185.3 4.9 1.3e-53 181.5 0.5 3.0 2 1 0 2 2 2 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 KNE02132.1 - 7.3e-49 166.2 1.1 1.3e-48 165.5 0.8 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 KNE02132.1 - 8.1e-36 123.5 3.6 2.2e-35 122.1 1.6 2.4 2 1 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.1 KNE02132.1 - 4.1e-30 105.2 0.0 8.9e-30 104.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 KNE02132.1 - 1e-10 41.8 1.0 4.5e-10 39.7 0.0 2.5 3 0 0 3 3 3 1 MATH domain Glyco_hydro_17 PF00332.13 KNE02137.1 - 1e-05 24.7 0.5 2.2e-05 23.6 0.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 dCMP_cyt_deam_1 PF00383.17 KNE02137.1 - 0.33 10.6 3.2 0.35 10.5 1.3 1.6 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region Macoilin PF09726.4 KNE02137.1 - 9.1 4.4 7.0 12 4.0 4.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Rap1-DNA-bind PF09197.5 KNE02138.1 - 5.8e-32 110.3 7.4 7.1e-29 100.4 0.4 2.7 3 0 0 3 3 3 2 Rap1, DNA-binding Rap1_C PF11626.3 KNE02138.1 - 2.6e-11 43.2 0.6 1.3e-10 41.0 0.0 2.5 3 0 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 KNE02138.1 - 2.4e-07 30.4 1.6 0.00061 19.5 0.1 2.8 2 0 0 2 2 2 2 Rap1 Myb domain Metallophos PF00149.23 KNE02139.1 - 2.2e-12 46.7 0.1 4.3e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KNE02139.1 - 1.1e-07 31.8 0.0 1.6e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RabGAP-TBC PF00566.13 KNE02140.1 - 5.3e-32 111.0 14.0 3e-28 98.7 4.3 2.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF3548 PF12068.3 KNE02140.1 - 0.0014 17.9 0.0 0.011 15.0 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3548) rRNA_proc-arch PF13234.1 KNE02141.1 - 1.5e-90 302.9 0.6 1.5e-90 302.9 0.4 1.9 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 KNE02141.1 - 1.2e-65 220.1 0.5 2.6e-65 219.0 0.4 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KNE02141.1 - 1.3e-21 76.8 0.0 1.2e-20 73.6 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNE02141.1 - 4.4e-07 29.6 0.0 1.2e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 KNE02141.1 - 0.038 12.8 0.0 0.13 11.1 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein ATG22 PF11700.3 KNE02142.1 - 0.017 13.6 1.4 0.024 13.1 1.0 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like YfhO PF09586.5 KNE02142.1 - 0.39 8.6 1.3 0.48 8.3 0.9 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Peptidase_S10 PF00450.17 KNE02143.1 - 4.4e-133 444.4 0.5 5.5e-133 444.1 0.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 KNE02143.1 - 6e-23 81.1 0.4 9.7e-23 80.4 0.3 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 KNE02143.1 - 0.0033 17.3 0.0 0.31 10.8 0.0 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Pkinase PF00069.20 KNE02144.1 - 4.4e-39 134.1 0.0 5.4e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE02144.1 - 1.1e-19 70.5 0.1 1.5e-19 70.1 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KNE02144.1 - 0.0006 18.9 0.4 0.0014 17.7 0.3 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KNE02144.1 - 0.00065 18.7 0.0 0.00081 18.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KNE02144.1 - 0.0034 17.1 0.0 0.084 12.5 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family SHMT PF00464.14 KNE02147.1 - 1.8e-206 685.2 0.0 2.1e-206 684.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 KNE02147.1 - 5.9e-05 22.1 0.1 0.00039 19.4 0.0 2.3 2 1 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KNE02147.1 - 0.022 13.9 0.0 0.056 12.5 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase Med16 PF11635.3 KNE02148.1 - 4.2e-179 597.0 0.0 5.5e-179 596.6 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 DUF3797 PF12677.2 KNE02148.1 - 0.013 15.0 0.2 0.039 13.5 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) DUF754 PF05449.6 KNE02149.1 - 0.017 15.1 0.0 0.017 15.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF754) Neurochondrin PF05536.6 KNE02150.1 - 0.0065 14.8 0.0 0.54 8.5 0.0 2.3 2 0 0 2 2 2 2 Neurochondrin Sec7 PF01369.15 KNE02151.1 - 4.9e-30 104.6 1.8 4.9e-30 104.6 1.2 2.2 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.1 KNE02151.1 - 0.0043 17.1 2.5 0.019 15.1 0.5 2.9 2 2 1 3 3 3 1 Pleckstrin homology domain Proteasome PF00227.21 KNE02152.1 - 6.8e-39 133.1 0.0 7.7e-39 132.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Cmc1 PF08583.5 KNE02153.1 - 1e-11 44.4 8.7 1.5e-11 43.9 6.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Lebercilin PF15619.1 KNE02153.1 - 0.0052 16.2 4.9 0.0063 15.9 3.4 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Takusan PF04822.8 KNE02153.1 - 0.0062 16.2 4.1 0.0098 15.6 2.8 1.4 1 0 0 1 1 1 1 Takusan CtIP_N PF10482.4 KNE02153.1 - 0.064 13.0 8.0 0.089 12.5 5.6 1.4 1 1 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain Ndufs5 PF10200.4 KNE02153.1 - 0.31 11.0 4.8 0.41 10.6 3.3 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa PLC-beta_C PF08703.5 KNE02153.1 - 0.51 10.0 11.5 0.3 10.7 5.7 1.7 1 1 1 2 2 2 0 PLC-beta C terminal DUF2870 PF11069.3 KNE02153.1 - 1.1 9.3 6.4 2.4 8.2 4.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) E1_dh PF00676.15 KNE02155.1 - 5.4e-119 396.3 0.4 6.5e-119 396.0 0.3 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KNE02155.1 - 0.00062 18.7 0.0 0.00098 18.1 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.1 KNE02155.1 - 0.84 10.3 5.5 3 8.5 0.3 3.1 2 2 1 3 3 3 0 KRTAP type 7 family Sec63 PF02889.11 KNE02157.1 - 3.8e-163 542.1 1.9 3.7e-81 272.7 0.1 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KNE02157.1 - 1.9e-47 160.8 0.1 1.2e-28 99.7 0.0 2.9 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 KNE02157.1 - 2.6e-15 56.7 0.1 1.9e-09 37.5 0.0 3.0 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KNE02157.1 - 5.9e-09 35.6 0.0 6.8e-08 32.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KNE02157.1 - 5.7e-08 32.9 0.3 4.8e-06 26.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 KNE02157.1 - 0.02 14.1 0.0 3.2 6.9 0.0 3.1 3 0 0 3 3 3 0 PhoH-like protein IstB_IS21 PF01695.12 KNE02157.1 - 0.023 14.1 0.8 3.3 7.0 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein DUF4250 PF14056.1 KNE02157.1 - 0.033 13.9 1.0 0.1 12.3 0.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) Glycos_transf_3 PF00591.16 KNE02159.1 - 1.8e-79 266.7 0.0 2.2e-79 266.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 KNE02159.1 - 8.5e-13 47.6 0.0 2.6e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain Microtub_assoc PF07989.6 KNE02160.1 - 0.0011 18.7 4.3 0.0011 18.7 2.9 10.7 8 3 4 13 13 13 1 Microtubule associated APG6 PF04111.7 KNE02160.1 - 0.0042 16.1 14.8 0.0042 16.1 10.3 8.5 1 1 8 9 9 9 5 Autophagy protein Apg6 DUF972 PF06156.8 KNE02160.1 - 0.014 15.7 5.8 0.014 15.7 4.0 11.1 2 1 8 10 10 10 0 Protein of unknown function (DUF972) Spc7 PF08317.6 KNE02160.1 - 2.3 6.8 122.4 0.16 10.5 8.6 6.5 2 1 1 5 5 5 0 Spc7 kinetochore protein DUF869 PF05911.6 KNE02160.1 - 2.6 6.1 115.2 0.055 11.6 5.5 6.1 1 1 3 5 5 5 0 Plant protein of unknown function (DUF869) Reo_sigmaC PF04582.7 KNE02160.1 - 6 5.9 41.7 0.6 9.2 3.1 6.1 1 1 4 7 7 7 0 Reovirus sigma C capsid protein Apc13p PF05839.6 KNE02161.1 - 0.0044 16.9 0.3 0.013 15.4 0.1 1.9 2 1 0 2 2 2 1 Apc13p protein RNA_pol_Rpb1_5 PF04998.12 KNE02163.1 - 6.8e-95 317.4 0.0 1.5e-94 316.3 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 KNE02163.1 - 2.5e-84 283.4 0.0 3.9e-84 282.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 KNE02163.1 - 1.5e-69 233.1 0.0 3.9e-69 231.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KNE02163.1 - 3.9e-39 133.9 0.0 1.2e-38 132.2 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KNE02163.1 - 3.1e-32 110.5 0.1 1.5e-31 108.3 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 DSS1_SEM1 PF05160.8 KNE02164.1 - 1.4e-21 76.0 17.9 1.5e-21 75.8 12.4 1.0 1 0 0 1 1 1 1 DSS1/SEM1 family AAA PF00004.24 KNE02165.1 - 6.9e-41 139.5 0.0 1.2e-40 138.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KNE02165.1 - 7.4e-05 22.8 3.3 0.009 16.0 0.0 3.3 3 1 1 4 4 4 1 AAA ATPase domain AAA_2 PF07724.9 KNE02165.1 - 8.5e-05 22.5 0.0 0.00022 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KNE02165.1 - 0.00048 19.2 0.1 0.0012 17.9 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KNE02165.1 - 0.00094 18.9 0.1 0.0065 16.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KNE02165.1 - 0.001 19.2 0.3 0.035 14.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 KNE02165.1 - 0.0021 17.9 0.0 0.0055 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 KNE02165.1 - 0.0084 15.3 0.2 0.026 13.7 0.1 1.8 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.8 KNE02165.1 - 0.0094 14.8 0.0 0.019 13.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 KNE02165.1 - 0.016 14.3 0.2 0.038 13.1 0.1 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KNE02165.1 - 0.016 14.9 0.3 0.039 13.7 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 KNE02165.1 - 0.018 14.4 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 KNE02165.1 - 0.037 13.4 1.3 0.28 10.5 0.2 2.3 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 KNE02165.1 - 0.038 14.7 0.1 0.13 13.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KNE02165.1 - 0.072 12.9 0.1 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KNE02165.1 - 0.075 12.6 0.1 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KNE02165.1 - 0.11 12.0 0.3 0.8 9.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Cation_efflux PF01545.16 KNE02170.1 - 1.2e-53 182.0 6.4 1.2e-53 182.0 4.4 3.0 2 1 1 3 3 3 1 Cation efflux family Epiglycanin_C PF14654.1 KNE02170.1 - 0.15 12.0 10.1 0.11 12.5 3.3 2.6 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region SelP_N PF04592.9 KNE02170.1 - 7.1 5.9 11.4 12 5.2 7.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ATP_bind_1 PF03029.12 KNE02171.1 - 1.4e-81 273.5 0.0 1.6e-81 273.3 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 KNE02171.1 - 0.00061 19.3 0.0 0.0018 17.8 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain ArgK PF03308.11 KNE02171.1 - 0.0015 17.3 0.0 0.0023 16.7 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_17 PF13207.1 KNE02171.1 - 0.0028 18.4 0.0 0.0064 17.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 KNE02171.1 - 0.012 15.0 0.0 0.28 10.5 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KNE02171.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 KNE02171.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 KNE02171.1 - 0.073 13.2 0.0 0.23 11.6 0.0 1.8 2 0 0 2 2 2 0 RNA helicase KAP_NTPase PF07693.9 KNE02171.1 - 0.085 11.8 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain CbiA PF01656.18 KNE02171.1 - 0.085 12.2 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.1 KNE02171.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Fer4_NifH PF00142.13 KNE02171.1 - 0.14 11.3 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_33 PF13671.1 KNE02171.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KNE02171.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Mlo PF03094.10 KNE02174.1 - 1.5 6.8 7.7 10 4.1 5.4 1.8 1 1 1 2 2 2 0 Mlo family Baculo_LEF5 PF04838.7 KNE02176.1 - 0.054 13.2 0.3 0.069 12.9 0.2 1.1 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 CTP_synth_N PF06418.9 KNE02177.1 - 0.0071 15.4 0.0 0.0084 15.2 0.0 1.0 1 0 0 1 1 1 1 CTP synthase N-terminus DUF3211 PF11485.3 KNE02177.1 - 0.043 13.8 0.1 0.048 13.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3211) Peptidase_M13 PF01431.16 KNE02178.1 - 0.081 12.0 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M13 TIP49 PF06068.8 KNE02180.1 - 2.3e-184 612.7 0.1 2.8e-184 612.4 0.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 KNE02180.1 - 1.6e-11 43.7 1.3 7.4e-08 31.7 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 KNE02180.1 - 3.5e-10 40.1 0.2 2.1e-06 27.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KNE02180.1 - 5.6e-06 26.4 0.2 0.024 14.6 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 KNE02180.1 - 0.00028 20.6 0.1 0.83 9.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KNE02180.1 - 0.00031 20.8 0.1 0.56 10.3 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KNE02180.1 - 0.0023 17.8 0.0 1.3 8.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 KNE02180.1 - 0.004 16.2 0.1 0.01 14.9 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 KNE02180.1 - 0.0062 15.7 0.2 0.62 9.1 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KNE02180.1 - 0.018 14.5 0.1 7.4 6.0 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 KNE02180.1 - 0.041 13.8 0.0 0.099 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KNE02180.1 - 0.046 13.1 0.1 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 KNE02180.1 - 0.072 12.7 0.0 12 5.4 0.0 2.5 2 1 0 2 2 2 0 Bacterial dnaA protein AAA_19 PF13245.1 KNE02180.1 - 0.08 12.7 0.5 0.27 11.0 0.1 2.1 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 KNE02180.1 - 0.092 12.4 0.1 1.8 8.1 0.0 2.4 2 0 0 2 2 2 0 NACHT domain DnaB_C PF03796.10 KNE02180.1 - 0.092 11.6 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain IstB_IS21 PF01695.12 KNE02180.1 - 0.1 12.0 0.1 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sec1 PF00995.18 KNE02181.1 - 2e-135 452.6 2.3 2.3e-135 452.4 1.6 1.0 1 0 0 1 1 1 1 Sec1 family Lebercilin PF15619.1 KNE02181.1 - 0.057 12.8 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease TMEMspv1-c74-12 PF11044.3 KNE02183.1 - 0.024 14.2 0.4 0.024 14.1 0.3 1.1 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Peptidase_C7 PF01830.13 KNE02188.1 - 0.0027 16.8 0.1 0.0032 16.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase C7 family Activator_LAG-3 PF11498.3 KNE02189.1 - 0.039 12.7 0.4 0.039 12.7 0.3 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PP2 PF14299.1 KNE02190.1 - 0.0092 15.3 0.0 0.0095 15.3 0.0 1.1 1 0 0 1 1 1 1 Phloem protein 2 mRNA_cap_C PF03919.10 KNE02192.1 - 0.07 13.4 2.0 0.078 13.3 1.4 1.2 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Tom37_C PF11801.3 KNE02195.1 - 0.012 15.5 0.6 0.013 15.4 0.4 1.0 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF1168 PF06658.7 KNE02195.1 - 0.023 14.1 19.6 0.028 13.9 13.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) EIIBC-GUT_N PF03612.9 KNE02195.1 - 0.19 11.3 1.2 0.21 11.1 0.9 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus U79_P34 PF03064.11 KNE02195.1 - 0.22 11.0 8.8 0.24 10.8 6.1 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 SR-25 PF10500.4 KNE02195.1 - 0.42 10.0 15.2 0.46 9.9 10.6 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RNA_polI_A34 PF08208.6 KNE02195.1 - 2.4 7.7 16.6 2.7 7.6 11.5 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 BLVR PF06375.6 KNE02195.1 - 2.6 7.8 15.0 3 7.6 10.4 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) RNase_H2-Ydr279 PF09468.5 KNE02195.1 - 3.1 6.9 13.5 3.7 6.6 9.4 1.0 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Peptidase_S49_N PF08496.5 KNE02195.1 - 3.2 7.5 9.9 3.6 7.3 6.8 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal YqfQ PF14181.1 KNE02195.1 - 3.8 7.5 8.4 4.3 7.3 5.8 1.1 1 0 0 1 1 1 0 YqfQ-like protein Med19 PF10278.4 KNE02195.1 - 4.9 6.7 16.1 5.5 6.6 11.1 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Cpn60_TCP1 PF00118.19 KNE02196.1 - 4.5e-146 487.2 0.7 5.1e-146 487.0 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ras PF00071.17 KNE02199.1 - 1.1e-55 187.4 0.0 1.3e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNE02199.1 - 1.7e-16 60.7 0.0 3.3e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNE02199.1 - 7.6e-08 31.7 0.0 1.3e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KNE02199.1 - 0.0015 18.0 0.0 0.0065 15.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KNE02199.1 - 0.0088 15.2 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KNE02199.1 - 0.01 15.0 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Isy1 PF06246.7 KNE02199.1 - 0.13 11.6 0.3 0.18 11.1 0.2 1.1 1 0 0 1 1 1 0 Isy1-like splicing family zf-CHCC PF10276.4 KNE02201.1 - 8.6e-15 54.3 0.4 1.3e-14 53.6 0.3 1.3 1 0 0 1 1 1 1 Zinc-finger domain zf-C2H2_3 PF13878.1 KNE02201.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO LrgB PF04172.11 KNE02202.1 - 2.2e-21 76.0 3.3 2.2e-21 76.0 2.3 4.2 4 1 1 5 5 5 3 LrgB-like family RNase_PH PF01138.16 KNE02203.1 - 2.3e-17 63.5 0.0 5.1e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KNE02203.1 - 7.4e-07 29.0 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Phytoreo_S7 PF07236.6 KNE02203.1 - 0.013 13.8 0.0 0.021 13.1 0.0 1.3 1 0 0 1 1 1 0 Phytoreovirus S7 protein Band_7 PF01145.20 KNE02204.1 - 7.6e-30 104.1 0.2 1.2e-29 103.4 0.1 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KNE02204.1 - 0.014 14.8 0.4 0.036 13.5 0.0 1.8 2 1 0 2 2 2 0 SPFH domain-Band 7 family Cys_rich_CPCC PF14206.1 KNE02204.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Cysteine-rich CPCC Gly_transf_sug PF04488.10 KNE02205.1 - 1.6e-20 73.4 0.0 3.2e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KNE02205.1 - 0.021 13.3 2.7 0.24 9.8 0.3 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Acyltransferase PF01553.16 KNE02206.1 - 3e-16 59.0 0.1 6.2e-16 58.0 0.1 1.5 1 0 0 1 1 1 1 Acyltransferase CLN3 PF02487.12 KNE02207.1 - 6.1e-103 344.7 21.5 1.6e-100 336.7 14.9 2.0 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.11 KNE02207.1 - 1.5 7.4 32.9 34 3.0 22.1 2.4 1 1 0 1 1 1 0 Major Facilitator Superfamily DAHP_synth_1 PF00793.15 KNE02208.1 - 8.3e-99 329.6 0.0 1e-98 329.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF218 PF02698.12 KNE02209.1 - 1.9e-05 24.2 0.0 2.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain HlyIII PF03006.15 KNE02210.1 - 7.1e-50 169.4 17.8 8.8e-50 169.1 12.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related ApoO PF09769.4 KNE02210.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein O DUF619 PF04768.8 KNE02211.1 - 4.4e-36 123.8 0.2 1.2e-35 122.4 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF619) RepB-RCR_reg PF10723.4 KNE02211.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Replication regulatory protein RepB Sld5 PF05916.6 KNE02212.1 - 2.6e-16 59.8 0.7 3.7e-16 59.3 0.5 1.2 1 0 0 1 1 1 1 GINS complex protein Chitin_synth_1 PF01644.12 KNE02213.1 - 4.9e-83 276.8 1.1 7.7e-83 276.1 0.7 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 KNE02213.1 - 5.4e-29 100.9 1.5 2.7e-21 75.5 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 KNE02213.1 - 6.1e-25 86.7 0.1 2.6e-24 84.7 0.0 2.1 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 KNE02213.1 - 5.2e-09 36.0 11.3 5.9e-09 35.9 4.9 2.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KNE02213.1 - 2e-07 31.0 0.0 7.2e-07 29.2 0.0 2.0 3 0 0 3 3 3 1 Glycosyltransferase like family 2 DUF805 PF05656.9 KNE02213.1 - 4.9 6.9 17.3 2.2 8.1 6.7 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF805) RCC1 PF00415.13 KNE02216.1 - 8.8e-60 198.7 12.2 2.5e-12 46.8 0.2 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KNE02216.1 - 4.3e-34 115.3 28.3 6e-08 32.0 0.1 7.0 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 KNE02216.1 - 0.072 12.5 1.1 8.5 5.9 0.0 3.4 4 0 0 4 4 4 0 Putative carbohydrate binding domain Arrestin_C PF02752.17 KNE02219.1 - 1.5e-17 63.9 0.0 3.8e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KNE02219.1 - 3.3e-14 52.9 0.0 7.6e-09 35.5 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KNE02219.1 - 0.013 14.9 0.0 0.038 13.4 0.0 1.7 2 0 0 2 2 2 0 Arrestin_N terminal like SNARE PF05739.14 KNE02220.1 - 4.2e-15 55.1 1.4 4.2e-15 55.1 1.0 2.8 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 KNE02220.1 - 1.6e-05 25.0 4.0 1.6e-05 25.0 2.7 3.0 3 1 1 4 4 4 1 Syntaxin Peptidase_M28 PF04389.12 KNE02220.1 - 0.021 14.5 0.1 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 Peptidase family M28 DUF3357 PF11837.3 KNE02220.1 - 0.03 14.1 0.0 0.072 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) LMBR1 PF04791.11 KNE02220.1 - 0.13 10.8 2.0 0.21 10.1 1.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3753 PF12575.3 KNE02220.1 - 0.18 11.6 2.2 1 9.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) DUF3450 PF11932.3 KNE02220.1 - 1.6 7.8 10.4 0.31 10.2 2.7 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) SUR7 PF06687.7 KNE02221.1 - 2.7e-20 72.8 22.7 2.7e-20 72.8 15.7 1.4 2 0 0 2 2 2 1 SUR7/PalI family Herpes_LMP1 PF05297.6 KNE02221.1 - 0.053 12.4 0.0 0.053 12.4 0.0 2.4 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) FA_desaturase PF00487.19 KNE02221.1 - 8.2 5.7 7.2 17 4.7 4.5 1.9 1 1 0 1 1 1 0 Fatty acid desaturase PIP5K PF01504.13 KNE02222.1 - 3.5e-61 206.5 4.7 3.5e-61 206.5 3.2 2.3 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 KNE02222.1 - 1.2e-23 83.5 0.0 2.6e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 KNE02222.1 - 9.3e-15 54.2 10.8 9.3e-15 54.2 7.5 2.1 2 0 0 2 2 2 1 FYVE zinc finger GPP34 PF05719.6 KNE02225.1 - 2.7e-61 207.2 0.0 3.4e-61 206.9 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Glyco_hydro_18 PF00704.23 KNE02226.1 - 1.3e-70 238.5 6.0 1.6e-70 238.2 4.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Herpes_US9 PF06072.6 KNE02226.1 - 0.29 11.0 1.4 0.51 10.2 0.1 2.1 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 UCH PF00443.24 KNE02227.1 - 1e-44 152.6 0.4 1.7e-44 151.9 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KNE02227.1 - 4.1e-24 84.4 11.1 6.5e-20 71.0 5.5 2.9 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KNE02227.1 - 3.5e-20 72.6 0.5 3.5e-20 72.6 0.4 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 KNE02227.1 - 2.6e-19 68.4 0.3 6.4e-09 35.3 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain A2M_comp PF07678.9 KNE02227.1 - 0.12 11.6 0.0 0.25 10.5 0.0 1.5 1 0 0 1 1 1 0 A-macroglobulin complement component DAHP_synth_1 PF00793.15 KNE02229.1 - 3e-80 268.8 0.0 3.4e-80 268.6 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family AA_permease_2 PF13520.1 KNE02230.1 - 6e-49 166.7 52.1 7.2e-49 166.4 36.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KNE02230.1 - 4.6e-30 104.3 43.3 6.1e-30 103.9 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2910 PF11139.3 KNE02230.1 - 0.011 14.9 13.9 0.16 11.0 1.5 3.5 2 2 0 2 2 2 0 Protein of unknown function (DUF2910) GWT1 PF06423.7 KNE02230.1 - 1.3 9.1 8.8 0.31 11.1 2.6 2.5 2 1 1 3 3 3 0 GWT1 DUF2678 PF10856.3 KNE02230.1 - 6 6.6 17.2 0.05 13.3 1.7 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF2678) MatE PF01554.13 KNE02231.1 - 6.4e-68 227.4 26.1 2.2e-36 124.9 6.6 2.3 2 0 0 2 2 2 2 MatE Glyco_hydro_76 PF03663.9 KNE02233.1 - 3.5e-134 447.8 18.0 4.3e-134 447.5 12.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 HAD_2 PF13419.1 KNE02235.1 - 1.3e-19 71.0 0.0 2.5e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KNE02235.1 - 4.7e-05 23.0 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Fungal_trans_2 PF11951.3 KNE02236.1 - 2.9e-41 141.3 1.0 5.8e-41 140.3 0.7 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNE02236.1 - 5.2e-08 32.6 7.6 1.7e-07 31.0 5.3 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Adap_comp_sub PF00928.16 KNE02237.1 - 1e-50 172.2 0.3 1e-50 172.2 0.2 1.6 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KNE02237.1 - 0.0064 16.2 1.0 0.18 11.5 0.1 2.5 2 0 0 2 2 2 1 Clathrin adaptor complex small chain INO80_Ies4 PF08193.6 KNE02237.1 - 0.012 15.6 0.5 0.49 10.3 0.0 2.3 2 0 0 2 2 2 0 INO80 complex subunit Ies4 Pterin_4a PF01329.14 KNE02238.1 - 1.9e-21 75.5 0.8 2.7e-21 75.1 0.6 1.3 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase DUF1670 PF07900.6 KNE02238.1 - 0.0057 15.9 0.3 0.0082 15.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1670) HA2 PF04408.18 KNE02240.1 - 1.7e-21 76.1 0.0 7.1e-21 74.1 0.0 2.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KNE02240.1 - 5.1e-13 48.6 0.0 2.7e-12 46.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 KNE02240.1 - 9.1e-09 35.1 0.0 2.7e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 KNE02240.1 - 5.3e-08 33.0 1.0 4.5e-07 30.0 0.0 2.9 3 1 0 3 3 3 1 AAA domain DEAD PF00270.24 KNE02240.1 - 4.5e-07 29.5 0.0 1.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 KNE02240.1 - 0.00037 19.5 0.0 0.012 14.5 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein KaiC PF06745.8 KNE02240.1 - 0.024 13.7 0.2 0.14 11.2 0.0 2.2 2 0 0 2 2 2 0 KaiC ResIII PF04851.10 KNE02240.1 - 0.045 13.5 5.4 0.58 9.9 0.0 4.2 4 1 0 4 4 4 0 Type III restriction enzyme, res subunit Synaptobrevin PF00957.16 KNE02241.1 - 3.4e-24 84.2 0.2 6.1e-24 83.4 0.2 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KNE02241.1 - 0.058 12.9 0.0 0.14 11.7 0.0 1.6 1 1 0 1 1 1 0 Regulated-SNARE-like domain DUF912 PF06024.7 KNE02241.1 - 3.6 7.7 5.7 2.7 8.0 2.6 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CBFD_NFYB_HMF PF00808.18 KNE02242.1 - 2e-07 30.9 0.1 3.3e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KNE02242.1 - 5.4e-06 26.4 0.1 8.4e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 BUD22 PF09073.5 KNE02242.1 - 0.0063 15.6 20.5 0.0066 15.5 14.2 1.2 1 0 0 1 1 1 1 BUD22 MOZ_SAS PF01853.13 KNE02243.1 - 1.4e-43 148.3 0.1 2e-43 147.8 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family SNF2_N PF00176.18 KNE02244.1 - 5.4e-69 232.2 0.0 8.4e-69 231.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KNE02244.1 - 1.5e-12 47.1 0.0 5.4e-12 45.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.6 KNE02244.1 - 7.2e-12 45.1 0.0 4.7e-11 42.5 0.0 2.4 2 0 0 2 2 2 1 HIRAN domain zf-RING_2 PF13639.1 KNE02244.1 - 6.6e-08 32.2 8.9 1.6e-07 30.9 6.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KNE02244.1 - 1.3e-05 24.7 9.8 2.6e-05 23.7 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNE02244.1 - 2e-05 24.1 8.7 4e-05 23.2 6.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KNE02244.1 - 2.3e-05 24.2 9.2 5.1e-05 23.2 6.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KNE02244.1 - 0.0046 17.0 5.3 0.013 15.6 3.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KNE02244.1 - 0.0096 15.7 2.3 0.02 14.7 1.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KNE02244.1 - 0.035 13.9 8.8 0.082 12.7 6.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KNE02244.1 - 0.061 13.0 3.8 0.15 11.7 2.6 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 KNE02244.1 - 0.14 11.8 5.6 0.29 10.7 3.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.16 KNE02244.1 - 4.5 7.2 7.2 2.6 7.9 3.4 1.8 1 1 0 1 1 1 0 IBR domain Nramp PF01566.13 KNE02246.1 - 1e-90 304.1 16.5 6.4e-90 301.5 11.4 2.0 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein DUF1352 PF07086.7 KNE02246.1 - 1.6 8.2 8.3 0.1 12.2 1.4 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1352) RMP PF14996.1 KNE02247.1 - 0.05 13.5 1.1 0.064 13.1 0.7 1.2 1 0 0 1 1 1 0 Retinal Maintenance NTF-like PF14540.1 KNE02248.1 - 0.054 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase-like Nfu_N PF08712.6 KNE02249.1 - 1.5e-27 94.9 0.0 3.6e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 KNE02249.1 - 2.9e-22 78.1 0.1 4.8e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain DUF445 PF04286.7 KNE02249.1 - 0.11 12.0 0.7 0.14 11.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) MotA_activ PF09114.5 KNE02249.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Transcription factor MotA, activation domain PHO4 PF01384.15 KNE02251.1 - 1e-109 366.1 20.7 1.2e-109 365.9 14.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family F_actin_cap_B PF01115.12 KNE02252.1 - 1.7e-96 322.1 0.2 2e-96 321.8 0.1 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Hexokinase_1 PF00349.16 KNE02253.1 - 0.75 9.0 4.2 5.8 6.1 0.0 2.9 3 0 0 3 3 3 0 Hexokinase Clathrin_lg_ch PF01086.12 KNE02255.1 - 1.8e-60 204.6 20.8 2e-60 204.5 14.4 1.0 1 0 0 1 1 1 1 Clathrin light chain DUF3541 PF12060.3 KNE02255.1 - 0.038 13.2 0.4 0.064 12.5 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) MHC_I PF00129.13 KNE02255.1 - 0.069 12.4 2.1 0.11 11.7 1.5 1.4 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 Phage_CP76 PF06892.6 KNE02255.1 - 0.11 11.7 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) DUF830 PF05708.7 KNE02255.1 - 0.12 12.3 0.2 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Orthopoxvirus protein of unknown function (DUF830) DUF2564 PF10819.3 KNE02255.1 - 2.1 8.5 7.9 0.89 9.7 0.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2564) V_ATPase_I PF01496.14 KNE02255.1 - 2.6 5.8 4.1 2.6 5.7 2.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WD40 PF00400.27 KNE02256.1 - 7e-55 181.0 13.6 9.3e-09 34.8 0.4 11.2 11 0 0 11 11 11 8 WD domain, G-beta repeat CPSF_A PF03178.10 KNE02256.1 - 0.0003 19.9 0.4 3.4 6.6 0.0 3.5 3 0 0 3 3 3 2 CPSF A subunit region Gmad1 PF10647.4 KNE02256.1 - 0.0003 20.2 0.1 0.0039 16.6 0.1 2.6 3 1 0 3 3 3 1 Lipoprotein LpqB beta-propeller domain Med20 PF08612.6 KNE02257.1 - 5.1e-22 78.1 0.0 5.6e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DEAD PF00270.24 KNE02258.1 - 2.1e-45 154.2 0.2 1.7e-44 151.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KNE02258.1 - 3e-24 84.3 0.0 7.4e-24 83.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KNE02258.1 - 1e-18 66.9 0.0 2.3e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 KNE02258.1 - 0.01 15.8 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain RNA_pol_Rpc4 PF05132.9 KNE02259.1 - 2.5e-17 63.0 3.2 3.6e-17 62.5 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase III RPC4 Peptidase_U49 PF10463.4 KNE02259.1 - 0.025 14.3 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase U49 Sas10 PF09368.5 KNE02260.1 - 2.6e-26 91.6 11.0 2.6e-26 91.6 7.7 2.2 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 KNE02260.1 - 1.7e-10 40.9 0.6 4.9e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Cpn60_TCP1 PF00118.19 KNE02261.1 - 1.3e-138 462.6 11.7 1.5e-138 462.4 8.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family D123 PF07065.9 KNE02262.1 - 1.2e-86 290.4 0.4 1.4e-86 290.2 0.3 1.0 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 KNE02262.1 - 0.084 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) SGL PF08450.7 KNE02263.1 - 7.4e-30 104.1 0.0 8.6e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 KNE02263.1 - 9.5e-05 22.3 0.1 0.0039 17.1 0.0 2.6 3 0 0 3 3 3 1 Strictosidine synthase zf-HIT PF04438.11 KNE02264.1 - 1.5e-08 34.1 10.2 1.5e-08 34.1 7.0 1.6 2 0 0 2 2 2 1 HIT zinc finger zf-MYND PF01753.13 KNE02264.1 - 0.0013 18.6 8.2 0.002 17.9 5.7 1.3 1 0 0 1 1 1 1 MYND finger Paramyxo_C PF01692.13 KNE02264.1 - 0.014 15.0 1.1 0.016 14.7 0.8 1.1 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c YfkD PF14167.1 KNE02264.1 - 0.046 12.7 0.3 0.053 12.5 0.2 1.1 1 0 0 1 1 1 0 YfkD-like protein Tnp_zf-ribbon_2 PF13842.1 KNE02264.1 - 0.067 13.6 8.3 0.14 12.5 5.8 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon zf-B_box PF00643.19 KNE02264.1 - 0.12 12.3 6.2 0.22 11.4 4.3 1.4 1 0 0 1 1 1 0 B-box zinc finger Cyclin_N PF00134.18 KNE02266.1 - 0.00017 21.1 0.2 0.0003 20.3 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KNE02266.1 - 0.021 15.2 0.5 0.035 14.5 0.4 1.4 1 0 0 1 1 1 0 Cyclin Fungal_trans PF04082.13 KNE02271.1 - 4.9e-17 61.6 2.6 1.1e-16 60.5 1.8 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNE02271.1 - 2e-09 37.1 11.4 3.5e-09 36.3 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.1 KNE02273.1 - 4e-09 36.3 18.5 4.6e-06 26.6 3.3 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KNE02273.1 - 2.7e-08 33.6 14.5 0.00016 21.7 1.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNE02273.1 - 6.6e-05 22.9 15.7 0.0013 18.9 0.9 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KNE02273.1 - 1.3 9.2 3.7 2.3 8.4 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FRG2 PF15315.1 KNE02274.1 - 5.4 6.9 7.5 5.8 6.8 5.2 1.1 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 HEAT_PBS PF03130.11 KNE02276.1 - 0.13 12.7 0.4 0.23 12.0 0.3 1.5 1 0 0 1 1 1 0 PBS lyase HEAT-like repeat ACC_epsilon PF13822.1 KNE02276.1 - 0.17 12.2 1.7 0.28 11.5 1.2 1.4 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Cyclin PF08613.6 KNE02277.1 - 0.004 17.5 0.2 0.023 15.1 0.0 2.1 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 KNE02277.1 - 0.0048 16.4 0.0 0.0076 15.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain CHZ PF09649.5 KNE02278.1 - 5.6e-19 67.0 2.7 5.6e-19 67.0 1.9 2.4 2 0 0 2 2 2 1 Histone chaperone domain CHZ LSM PF01423.17 KNE02279.1 - 1.2e-17 63.2 0.4 1.6e-17 62.7 0.3 1.2 1 0 0 1 1 1 1 LSM domain DUF4394 PF14339.1 KNE02279.1 - 0.075 12.3 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4394) Misat_Tub_SegII PF10644.4 KNE02279.1 - 0.11 12.5 0.1 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Ras PF00071.17 KNE02280.1 - 5.3e-59 198.2 0.1 6.2e-59 198.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNE02280.1 - 2.1e-21 76.6 0.0 3.5e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNE02280.1 - 2.4e-12 46.4 0.0 3e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KNE02280.1 - 7.1e-07 29.1 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KNE02280.1 - 0.0003 20.2 0.0 0.00078 18.9 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KNE02280.1 - 0.00054 20.1 0.1 0.042 13.9 0.0 2.1 1 1 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 KNE02280.1 - 0.0022 17.0 0.0 0.0025 16.8 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain DUF258 PF03193.11 KNE02280.1 - 0.0066 15.6 0.1 0.013 14.7 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 KNE02280.1 - 0.0068 15.4 0.0 0.0093 15.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.7 KNE02280.1 - 0.01 14.9 0.0 0.024 13.7 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 KNE02280.1 - 0.013 15.5 0.5 0.035 14.0 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 KNE02280.1 - 0.013 15.7 0.0 0.017 15.4 0.0 1.6 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.5 KNE02280.1 - 0.038 13.2 0.0 0.072 12.3 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.10 KNE02280.1 - 0.044 13.5 0.1 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 NTPase PduV-EutP PF10662.4 KNE02280.1 - 0.064 12.7 0.0 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 KNE02280.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B SPT16 PF08644.6 KNE02281.1 - 1.6e-51 174.1 0.2 1.6e-51 174.1 0.1 2.8 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 KNE02281.1 - 2.4e-48 163.7 2.4 2.5e-47 160.4 1.7 2.6 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 KNE02281.1 - 1.3e-19 70.6 0.0 2.2e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 KNE02281.1 - 1.9e-19 69.4 0.1 9.4e-19 67.2 0.0 2.3 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Creatinase_N PF01321.13 KNE02281.1 - 0.0027 18.2 0.1 0.036 14.5 0.0 2.6 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain DNA_primase_lrg PF04104.9 KNE02283.1 - 4.1e-76 255.6 0.0 6e-76 255.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DUF932 PF06067.6 KNE02283.1 - 0.0068 15.7 0.0 0.016 14.5 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF932) PEX11 PF05648.9 KNE02284.1 - 0.0015 17.8 3.1 0.98 8.6 0.1 3.1 3 0 0 3 3 3 3 Peroxisomal biogenesis factor 11 (PEX11) YMF19 PF02326.10 KNE02284.1 - 0.37 11.4 3.6 0.58 10.7 2.0 1.8 1 1 0 1 1 1 0 Plant ATP synthase F0 Xan_ur_permease PF00860.15 KNE02285.1 - 6.8e-69 232.2 30.3 9.8e-69 231.6 21.0 1.2 1 0 0 1 1 1 1 Permease family LicD PF04991.8 KNE02289.1 - 5.5e-47 160.5 0.9 5.5e-47 160.5 0.6 3.2 4 0 0 4 4 4 1 LicD family HLH PF00010.21 KNE02290.1 - 3.3e-14 52.2 2.1 3.3e-14 52.2 1.5 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAT1 PF09770.4 KNE02290.1 - 0.045 11.9 19.0 0.052 11.8 13.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neuro_bHLH PF12533.3 KNE02290.1 - 0.13 13.1 10.7 0.24 12.2 7.4 1.5 1 0 0 1 1 1 0 Neuronal helix-loop-helix transcription factor Macoilin PF09726.4 KNE02290.1 - 0.58 8.3 15.0 0.75 8.0 4.3 2.2 2 0 0 2 2 2 0 Transmembrane protein DivIC PF04977.10 KNE02290.1 - 3.1 7.3 13.2 2.7 7.5 1.6 2.8 2 1 0 2 2 2 0 Septum formation initiator Pex14_N PF04695.8 KNE02290.1 - 8.1 6.4 13.4 19 5.2 9.2 1.8 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TPP_enzyme_M PF00205.17 KNE02291.1 - 1.4e-36 125.2 0.0 1.1e-35 122.3 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 KNE02291.1 - 5.5e-33 113.8 0.0 8.6e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KNE02291.1 - 3.5e-12 46.1 0.0 7e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain MHC_II_beta PF00969.14 KNE02291.1 - 0.15 12.0 0.0 0.42 10.6 0.0 1.7 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain OCC1 PF15506.1 KNE02291.1 - 0.15 11.9 0.4 16 5.4 0.0 2.5 2 0 0 2 2 2 0 OCC1 family ABC_membrane PF00664.18 KNE02292.1 - 1.4e-36 126.3 16.7 1.7e-36 126.0 11.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KNE02292.1 - 2.6e-34 118.4 0.0 5.4e-34 117.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KNE02292.1 - 1.2e-08 35.2 0.1 0.00072 19.6 0.0 3.5 2 2 0 2 2 2 1 AAA domain SMC_N PF02463.14 KNE02292.1 - 4.5e-08 32.5 0.2 0.00011 21.5 0.0 2.7 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KNE02292.1 - 7.6e-05 23.5 0.7 0.00027 21.7 0.5 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KNE02292.1 - 0.00032 20.8 0.0 0.0044 17.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KNE02292.1 - 0.0004 20.4 0.2 0.0028 17.6 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 KNE02292.1 - 0.0011 18.4 0.1 0.0027 17.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KNE02292.1 - 0.0015 17.9 0.0 0.0032 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KNE02292.1 - 0.007 15.8 0.5 0.023 14.1 0.3 1.9 1 1 0 1 1 1 1 AAA-like domain MobB PF03205.9 KNE02292.1 - 0.025 14.2 0.0 0.078 12.6 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 KNE02292.1 - 0.034 14.0 0.0 0.16 11.9 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 KNE02292.1 - 0.049 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KNE02292.1 - 0.06 13.6 0.0 0.06 13.6 0.0 2.0 2 0 0 2 2 1 0 AAA domain DUF258 PF03193.11 KNE02292.1 - 0.11 11.7 1.0 0.41 9.8 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KNE02292.1 - 0.12 12.2 0.3 1.1 9.1 0.2 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Peptidase_M1 PF01433.15 KNE02295.1 - 5.4e-75 252.8 0.1 8.9e-75 252.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KNE02295.1 - 7.2e-64 216.0 2.6 9.7e-64 215.6 1.8 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KNE02295.1 - 6.6e-10 39.1 0.0 1.2e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily BCL9 PF11502.3 KNE02296.1 - 0.027 14.0 0.2 0.032 13.7 0.2 1.1 1 0 0 1 1 1 0 B-cell lymphoma 9 protein PseudoU_synth_1 PF01416.15 KNE02301.1 - 2.3e-23 82.6 0.0 4.5e-12 46.3 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase GvpO PF05800.6 KNE02301.1 - 0.046 13.6 0.0 4.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpO UPF0113 PF03657.8 KNE02303.1 - 4.8e-11 42.5 0.0 6.3e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) DAP3 PF10236.4 KNE02304.1 - 6.7e-57 192.7 0.1 1e-56 192.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.1 KNE02304.1 - 0.005 16.3 0.0 0.018 14.5 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 KNE02304.1 - 0.021 14.5 1.3 0.11 12.1 0.0 2.6 3 1 0 3 3 3 0 Archaeal ATPase DUF258 PF03193.11 KNE02304.1 - 0.022 13.9 0.0 0.048 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KNE02304.1 - 0.037 13.9 0.0 0.42 10.5 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain Tox-MPTase2 PF15638.1 KNE02304.1 - 0.074 12.5 0.6 0.16 11.5 0.4 1.5 1 0 0 1 1 1 0 Metallopeptidase toxin 2 ABC_tran PF00005.22 KNE02304.1 - 0.077 13.2 0.1 0.24 11.6 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Histone_HNS PF00816.16 KNE02304.1 - 1.6 9.2 7.0 1.2 9.6 0.7 2.8 3 0 0 3 3 3 0 H-NS histone family DEAD PF00270.24 KNE02305.1 - 3.3e-22 78.7 0.0 1.8e-21 76.3 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNE02305.1 - 1.1e-13 50.8 0.0 5.1e-13 48.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNE02305.1 - 3.1e-05 23.9 0.0 0.00013 21.8 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit BLVR PF06375.6 KNE02306.1 - 0.15 11.9 7.8 0.13 12.0 5.4 1.0 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Tryp_alpha_amyl PF00234.17 KNE02306.1 - 0.15 12.2 1.0 0.16 12.1 0.7 1.0 1 0 0 1 1 1 0 Protease inhibitor/seed storage/LTP family ETRAMP PF09716.5 KNE02306.1 - 1.1 9.2 6.4 1.1 9.3 4.4 1.1 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) FEZ PF07763.8 KNE02306.1 - 2.5 7.7 7.2 2.6 7.7 5.0 1.0 1 0 0 1 1 1 0 FEZ-like protein NUDIX PF00293.23 KNE02307.1 - 1.9e-12 46.9 0.0 3.4e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 KNE02307.1 - 1.2e-06 27.9 0.5 2.4e-06 26.9 0.3 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NUDIX-like PF09296.6 KNE02307.1 - 4.4e-05 23.7 0.0 9e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain DZR PF12773.2 KNE02307.1 - 0.13 12.0 0.3 0.27 11.0 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon GDPD PF03009.12 KNE02308.1 - 8.5e-24 84.4 0.1 6.3e-23 81.5 0.1 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family L_lactis_ph-MCP PF06673.6 KNE02308.1 - 0.034 12.9 0.1 0.049 12.3 0.1 1.1 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein SKIP_SNW PF02731.10 KNE02309.1 - 5.6e-42 142.8 8.0 9e-42 142.2 5.5 1.3 1 0 0 1 1 1 1 SKIP/SNW domain DUF2674 PF10879.3 KNE02309.1 - 0.074 12.7 0.8 0.79 9.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2674) GRDB PF07355.7 KNE02309.1 - 0.18 10.7 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) WAC_Acf1_DNA_bd PF10537.4 KNE02310.1 - 5.2e-40 135.7 1.5 5.2e-40 135.7 1.0 2.2 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 KNE02310.1 - 3.6e-09 36.2 0.8 8.7e-09 35.0 0.6 1.6 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 KNE02310.1 - 1.4e-06 27.9 0.2 4.4e-06 26.4 0.1 2.0 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 ADH_N PF08240.7 KNE02312.1 - 4.6e-22 77.8 5.9 7.2e-22 77.2 4.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KNE02312.1 - 5.6e-18 64.7 0.0 9.8e-18 63.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KNE02312.1 - 3.7e-05 22.9 0.0 7.1e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KNE02312.1 - 0.00086 18.9 1.0 0.0016 18.0 0.0 1.9 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain Ubiq_cyt_C_chap PF03981.7 KNE02313.1 - 2.4e-40 137.6 0.5 8.8e-40 135.8 0.2 1.9 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone Acetyltransf_9 PF13527.1 KNE02314.1 - 0.011 15.6 0.0 0.45 10.3 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KNE02314.1 - 0.019 15.0 0.0 0.046 13.8 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 KNE02316.1 - 3.8e-12 45.6 23.0 3.8e-12 45.6 15.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily SRP72 PF08492.7 KNE02317.1 - 5.5e-10 39.4 7.9 5.5e-10 39.4 5.4 2.7 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_12 PF13424.1 KNE02317.1 - 1e-06 28.5 7.5 0.0094 15.8 0.4 4.1 3 2 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KNE02317.1 - 2.3e-05 23.9 9.2 0.00024 20.6 0.3 4.3 4 1 0 4 4 4 1 TPR repeat TPR_14 PF13428.1 KNE02317.1 - 9.7e-05 22.6 2.8 7.4 7.5 0.0 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 KNE02317.1 - 0.00035 20.2 8.8 1.3 9.1 0.1 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 KNE02317.1 - 0.00065 19.3 9.5 1.7 8.6 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KNE02317.1 - 0.0017 18.9 4.5 13 6.6 0.1 4.3 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KNE02317.1 - 0.0018 17.7 9.3 1.4 8.6 0.4 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 KNE02317.1 - 0.005 17.2 1.9 61 4.4 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 KNE02317.1 - 0.0052 17.0 6.3 2.9 8.3 0.6 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_5 PF12688.2 KNE02317.1 - 0.0097 15.9 0.6 0.35 10.9 0.0 2.7 2 0 0 2 2 2 1 Tetratrico peptide repeat TPR_10 PF13374.1 KNE02317.1 - 0.012 15.5 1.8 21 5.2 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 KNE02317.1 - 0.08 12.8 2.4 3.2 7.6 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KNE02317.1 - 0.28 11.0 4.8 10 6.2 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat GCV_T PF01571.16 KNE02319.1 - 2.2e-62 210.1 0.0 2.8e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KNE02319.1 - 2.4e-16 59.5 0.0 4.1e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 KNE02319.1 - 0.0017 18.2 0.0 0.12 12.2 0.0 2.3 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family TrmE_N PF10396.4 KNE02319.1 - 0.067 13.1 0.0 17 5.3 0.0 2.3 2 0 0 2 2 2 0 GTP-binding protein TrmE N-terminus PI3_PI4_kinase PF00454.22 KNE02321.1 - 4.5e-47 160.5 0.0 9.8e-47 159.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 KNE02321.1 - 9e-20 70.9 2.3 9e-20 70.9 1.6 2.9 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 KNE02321.1 - 5.8e-14 51.2 0.0 1.5e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 FATC domain RRM_6 PF14259.1 KNE02323.1 - 5.5e-29 99.9 0.6 4.2e-07 29.8 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KNE02323.1 - 1.2e-23 82.5 3.2 6e-07 28.9 0.7 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNE02323.1 - 5.1e-23 80.6 3.6 2.6e-07 30.3 0.5 4.7 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KNE02323.1 - 0.0061 16.2 0.3 0.074 12.8 0.1 2.7 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif BAF1_ABF1 PF04684.8 KNE02323.1 - 0.0067 15.3 22.7 0.011 14.5 15.7 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor RRM_3 PF08777.6 KNE02323.1 - 0.23 11.3 0.8 0.55 10.1 0.3 1.7 2 0 0 2 2 2 0 RNA binding motif Use1 PF09753.4 KNE02324.1 - 1.6e-07 31.0 0.8 3e-07 30.1 0.2 1.6 2 1 0 2 2 2 1 Membrane fusion protein Use1 Cob_adeno_trans PF01923.13 KNE02324.1 - 0.099 12.4 1.2 1.2 8.8 0.0 2.4 2 1 0 2 2 2 0 Cobalamin adenosyltransferase Erp_C PF06780.6 KNE02324.1 - 0.62 9.9 4.9 2.6 7.8 0.5 2.3 1 1 0 2 2 2 0 Erp protein C-terminus Ribosomal_L14 PF00238.14 KNE02329.1 - 1.2e-21 76.7 0.0 1.3e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PH PF00169.24 KNE02330.1 - 4.9e-12 45.9 0.9 1.4e-11 44.5 0.6 1.8 1 0 0 1 1 1 1 PH domain zf-RING_2 PF13639.1 KNE02332.1 - 4.1e-11 42.5 4.6 5.9e-11 42.0 3.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KNE02332.1 - 1.2e-09 38.0 4.8 2e-09 37.3 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KNE02332.1 - 8e-09 35.0 4.3 1.5e-08 34.1 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KNE02332.1 - 4e-08 33.0 4.6 1.2e-07 31.5 3.3 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KNE02332.1 - 6.4e-08 32.1 4.2 1.1e-07 31.3 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KNE02332.1 - 2.2e-06 27.2 3.3 3.4e-06 26.6 0.6 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 KNE02332.1 - 5.7e-06 25.9 8.0 1.4e-05 24.7 5.5 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KNE02332.1 - 0.0054 16.8 3.0 0.013 15.5 2.1 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KNE02332.1 - 0.014 15.2 4.2 0.077 12.8 2.9 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KNE02332.1 - 0.024 14.1 6.1 0.16 11.6 4.3 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Tmpp129 PF10272.4 KNE02332.1 - 0.027 13.2 2.0 0.033 12.9 1.4 1.1 1 0 0 1 1 1 0 Putative transmembrane protein precursor FYVE PF01363.16 KNE02332.1 - 0.05 13.5 5.8 0.11 12.4 4.0 1.6 1 1 0 1 1 1 0 FYVE zinc finger TerY-C PF15616.1 KNE02332.1 - 0.092 12.6 6.8 2.9 7.8 4.8 2.2 1 1 0 1 1 1 0 TerY-C metal binding domain zf-Di19 PF05605.7 KNE02332.1 - 0.14 12.2 7.6 5.1 7.3 0.8 3.3 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding FANCL_C PF11793.3 KNE02332.1 - 0.17 11.8 4.0 0.66 9.9 2.7 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-MIZ PF02891.15 KNE02332.1 - 0.22 11.0 7.0 0.66 9.5 4.8 1.8 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_6 PF14835.1 KNE02332.1 - 0.66 9.7 3.9 42 4.0 2.9 2.8 2 1 1 3 3 3 0 zf-RING of BARD1-type protein DUF329 PF03884.9 KNE02332.1 - 1.4 8.5 4.7 17 5.0 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF329) Bax1-I PF01027.15 KNE02334.1 - 2.5e-49 167.6 25.5 2.9e-49 167.4 17.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 AAA PF00004.24 KNE02336.1 - 4.5e-40 136.8 0.0 7.2e-40 136.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KNE02336.1 - 1.2e-06 28.7 0.1 0.00018 21.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KNE02336.1 - 1.8e-05 24.7 0.0 6.9e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KNE02336.1 - 3.1e-05 23.0 0.0 5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 KNE02336.1 - 5.7e-05 22.8 0.1 0.00035 20.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KNE02336.1 - 0.00015 21.7 0.0 0.00038 20.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KNE02336.1 - 0.00062 18.8 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KNE02336.1 - 0.00087 19.2 0.3 0.0026 17.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KNE02336.1 - 0.0032 18.2 0.3 0.0075 17.0 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KNE02336.1 - 0.0039 17.0 0.0 0.0077 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KNE02336.1 - 0.0049 16.2 0.0 0.0094 15.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 KNE02336.1 - 0.0051 16.5 0.3 0.011 15.5 0.2 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_3 PF07726.6 KNE02336.1 - 0.0052 16.3 0.0 0.013 15.1 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KNE02336.1 - 0.0071 15.4 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 KNE02336.1 - 0.0091 15.8 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KNE02336.1 - 0.01 15.0 0.1 0.27 10.2 0.1 2.2 1 1 1 2 2 2 1 KaiC SKI PF01202.17 KNE02336.1 - 0.01 15.7 0.0 1 9.1 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase AAA_18 PF13238.1 KNE02336.1 - 0.011 15.9 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KNE02336.1 - 0.018 13.7 1.2 0.028 13.1 0.0 1.9 3 0 0 3 3 3 0 TIP49 C-terminus NB-ARC PF00931.17 KNE02336.1 - 0.022 13.6 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.1 KNE02336.1 - 0.023 14.0 0.8 0.14 11.5 0.3 2.1 1 1 0 2 2 2 0 AAA domain PhoH PF02562.11 KNE02336.1 - 0.028 13.6 1.2 0.13 11.4 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein NTPase_1 PF03266.10 KNE02336.1 - 0.03 14.0 0.9 0.21 11.2 0.0 2.7 3 1 1 4 4 3 0 NTPase RNA_helicase PF00910.17 KNE02336.1 - 0.031 14.4 0.0 0.06 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 KNE02336.1 - 0.035 13.7 0.2 0.093 12.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KNE02336.1 - 0.035 13.2 0.1 0.071 12.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KNE02336.1 - 0.04 13.5 0.1 0.23 11.1 0.1 2.1 2 0 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 KNE02336.1 - 0.098 12.7 0.0 0.24 11.4 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF2075 PF09848.4 KNE02336.1 - 0.12 11.3 0.1 0.18 10.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CPT PF07931.7 KNE02336.1 - 0.13 11.9 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Thioredoxin PF00085.15 KNE02337.1 - 3.9e-30 103.6 0.1 4.4e-30 103.4 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KNE02337.1 - 4.9e-06 26.7 0.1 6.2e-05 23.1 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 KNE02337.1 - 1.7e-05 24.3 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 KNE02337.1 - 1.8e-05 24.6 0.0 2.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 KNE02337.1 - 6.5e-05 22.9 0.0 9.8e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 KNE02337.1 - 0.0019 17.8 0.0 0.0045 16.6 0.0 1.6 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 KNE02337.1 - 0.0048 16.4 0.0 0.0058 16.1 0.0 1.3 1 0 0 1 1 1 1 Redoxin Phosducin PF02114.11 KNE02337.1 - 0.016 13.9 0.0 0.017 13.8 0.0 1.0 1 0 0 1 1 1 0 Phosducin CPL PF08144.6 KNE02338.1 - 2.9e-10 40.1 0.5 1.7e-08 34.4 0.0 3.7 4 1 1 5 5 5 1 CPL (NUC119) domain PUF PF00806.14 KNE02338.1 - 2.3e-08 33.0 0.7 0.15 11.6 0.0 4.6 4 0 0 4 4 4 3 Pumilio-family RNA binding repeat HD_assoc PF13286.1 KNE02338.1 - 0.087 13.0 1.7 19 5.6 0.0 4.0 3 1 1 4 4 4 0 Phosphohydrolase-associated domain SDA1 PF05285.7 KNE02338.1 - 0.1 11.8 27.8 0.23 10.7 19.3 1.7 1 0 0 1 1 1 0 SDA1 TMEM247 PF15444.1 KNE02338.1 - 0.96 9.2 6.3 1.8 8.3 4.4 1.4 1 0 0 1 1 1 0 Transmembrane protein 247 COPI_C PF06957.6 KNE02338.1 - 2.2 6.7 12.2 3.6 6.0 8.5 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Nop14 PF04147.7 KNE02338.1 - 4 5.2 34.8 7.6 4.3 24.1 1.4 1 0 0 1 1 1 0 Nop14-like family NDUFA12 PF05071.11 KNE02339.1 - 4.7e-08 33.4 5.1 1.3e-07 32.0 3.6 1.8 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 OmpH PF03938.9 KNE02339.1 - 0.022 14.6 5.5 0.04 13.8 3.8 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3166 PF11365.3 KNE02339.1 - 0.053 13.9 4.2 0.085 13.3 2.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3166) G6PD_N PF00479.17 KNE02339.1 - 0.1 12.8 1.2 0.16 12.2 0.9 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain MSA-2c PF12238.3 KNE02339.1 - 0.19 11.3 4.2 0.32 10.6 2.9 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c Exonuc_VII_L PF02601.10 KNE02339.1 - 0.33 10.1 5.9 0.41 9.7 4.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.14 KNE02339.1 - 0.45 8.3 5.2 0.5 8.1 3.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KNE02339.1 - 0.57 9.7 8.2 0.67 9.5 5.7 1.2 1 0 0 1 1 1 0 IncA protein FlaC_arch PF05377.6 KNE02339.1 - 0.61 10.0 4.5 1.1 9.1 2.9 1.6 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Stm1_N PF09598.5 KNE02339.1 - 0.69 10.6 4.1 1.4 9.6 2.9 1.5 1 0 0 1 1 1 0 Stm1 DUF4337 PF14235.1 KNE02339.1 - 2 8.2 8.7 2.9 7.7 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF972 PF06156.8 KNE02339.1 - 2.9 8.2 10.1 8.7 6.7 6.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Herpes_UL25 PF01499.11 KNE02339.1 - 3.9 5.6 7.7 4.4 5.4 5.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Mnd1 PF03962.10 KNE02339.1 - 4 7.0 16.1 7.8 6.1 11.2 1.5 1 1 0 1 1 1 0 Mnd1 family DivIC PF04977.10 KNE02339.1 - 5.2 6.6 12.6 2.8 7.4 5.7 2.2 1 1 1 2 2 2 0 Septum formation initiator Iron_traffic PF04362.9 KNE02339.1 - 5.7 6.4 8.5 0.55 9.7 2.7 1.7 1 1 1 2 2 2 0 Bacterial Fe(2+) trafficking PX PF00787.19 KNE02340.1 - 7.5e-16 57.9 0.0 9.1e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 PX domain Pyr_redox_2 PF07992.9 KNE02342.1 - 4.3e-28 98.5 0.1 5.5e-28 98.2 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KNE02342.1 - 8.3e-18 64.5 0.4 2.6e-15 56.5 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KNE02342.1 - 2e-10 41.0 0.0 1.7e-07 31.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KNE02342.1 - 8.9e-05 21.5 0.0 0.22 10.3 0.0 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 KNE02342.1 - 0.00019 20.4 1.7 2.3 6.9 0.1 3.6 3 1 1 4 4 4 3 Glucose inhibited division protein A Thi4 PF01946.12 KNE02342.1 - 0.00047 19.3 0.1 0.0063 15.6 0.0 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.1 KNE02342.1 - 0.0007 19.8 0.0 0.34 11.1 0.0 2.5 2 1 0 2 2 2 2 Putative NAD(P)-binding Shikimate_DH PF01488.15 KNE02342.1 - 0.0011 19.0 0.1 2.2 8.3 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 KNE02342.1 - 0.0015 17.5 0.2 1.4 7.7 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KNE02342.1 - 0.0049 16.8 0.1 0.031 14.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KNE02342.1 - 0.091 12.5 0.0 4 7.1 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding SNARE PF05739.14 KNE02343.1 - 3.7e-11 42.5 5.9 3.7e-11 42.5 4.1 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.1 KNE02343.1 - 3.9e-06 26.8 6.8 3.9e-06 26.8 4.7 2.5 2 0 0 2 2 2 1 Syntaxin-like protein Synaptobrevin PF00957.16 KNE02343.1 - 0.17 11.4 2.9 0.14 11.7 0.5 2.0 2 0 0 2 2 2 0 Synaptobrevin DUF2760 PF10816.3 KNE02343.1 - 0.23 10.9 1.5 5.7 6.4 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF2760) MCPsignal PF00015.16 KNE02343.1 - 0.34 10.4 7.6 0.48 9.9 3.7 2.1 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Laminin_II PF06009.7 KNE02343.1 - 2.5 7.8 8.9 5.6 6.7 0.4 3.0 1 1 2 3 3 3 0 Laminin Domain II DUF1664 PF07889.7 KNE02343.1 - 3 7.6 10.1 0.72 9.6 2.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) WD40 PF00400.27 KNE02344.1 - 2.9e-51 169.5 19.9 1.1e-10 41.0 0.1 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KNE02344.1 - 0.0003 20.2 0.2 0.23 10.9 0.0 4.4 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.1 KNE02344.1 - 0.044 13.5 0.1 7.6 6.3 0.0 3.7 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Hira PF07569.6 KNE02345.1 - 9.5e-83 276.7 1.4 2.6e-82 275.2 0.0 2.3 3 0 0 3 3 3 1 TUP1-like enhancer of split WD40 PF00400.27 KNE02345.1 - 2.3e-14 52.6 16.6 0.0041 16.9 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat HIRA_B PF09453.5 KNE02345.1 - 9.1e-11 41.0 0.6 2.2e-10 39.7 0.4 1.7 1 0 0 1 1 1 1 HIRA B motif Nbas_N PF15492.1 KNE02345.1 - 0.0091 15.1 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal CK_II_beta PF01214.13 KNE02346.1 - 5.8e-71 237.8 0.0 7e-71 237.5 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit tRNA-synt_1b PF00579.20 KNE02348.1 - 1e-67 228.3 0.0 1.4e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) NCD1 PF04904.8 KNE02348.1 - 0.14 11.9 0.0 0.44 10.3 0.0 1.8 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) GATA PF00320.22 KNE02349.1 - 0.12 11.7 1.5 0.7 9.2 0.1 2.3 2 0 0 2 2 2 0 GATA zinc finger PNP_UDP_1 PF01048.15 KNE02350.1 - 6.8e-52 175.7 0.0 8.4e-52 175.4 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily WD40 PF00400.27 KNE02351.1 - 2.1e-40 135.1 22.8 1.3e-11 43.8 0.2 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KNE02351.1 - 0.0066 16.1 10.2 0.19 11.4 0.4 3.7 3 1 1 4 4 4 2 Transcription factor IIIC subunit delta N-term DUF3915 PF13054.1 KNE02351.1 - 0.028 14.3 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) GCIP PF13324.1 KNE02352.1 - 0.058 12.6 3.8 0.081 12.1 2.4 1.5 1 1 1 2 2 2 0 Grap2 and cyclin-D-interacting Nsp1 PF11501.3 KNE02352.1 - 0.076 12.8 0.1 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Non structural protein Nsp1 DUF1789 PF08748.6 KNE02352.1 - 1.2 9.2 5.8 0.46 10.5 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1789) PhaP_Bmeg PF09602.5 KNE02353.1 - 0.041 13.7 0.5 0.088 12.6 0.4 1.5 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Hemerythrin PF01814.18 KNE02353.1 - 0.051 13.7 0.6 0.13 12.4 0.4 1.7 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain Ras PF00071.17 KNE02354.1 - 7.2e-24 83.9 0.0 1.1e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNE02354.1 - 4.4e-07 30.4 0.2 3.9e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 KNE02354.1 - 0.021 14.2 0.3 0.042 13.2 0.0 1.6 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain CPSase_L_D3 PF02787.14 KNE02354.1 - 0.036 13.8 0.4 0.059 13.1 0.3 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain NblA PF04485.7 KNE02354.1 - 0.047 13.5 0.4 0.047 13.5 0.3 2.1 1 1 1 2 2 2 0 Phycobilisome degradation protein nblA DUF3753 PF12575.3 KNE02354.1 - 0.26 11.1 1.4 0.49 10.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Resolvase PF00239.16 KNE02356.1 - 0.084 12.7 0.0 0.088 12.6 0.0 1.1 1 0 0 1 1 1 0 Resolvase, N terminal domain GST_N_2 PF13409.1 KNE02357.1 - 2.9e-23 81.6 0.1 1.7e-22 79.1 0.0 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KNE02357.1 - 7.5e-12 44.9 0.0 2.3e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KNE02357.1 - 2.4e-06 27.6 0.0 0.02 15.1 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KNE02357.1 - 0.00045 20.1 0.0 0.00094 19.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2365 PF10157.4 KNE02357.1 - 0.00074 19.4 0.1 0.0011 18.8 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) GST_C_3 PF14497.1 KNE02357.1 - 0.0046 17.4 0.0 0.0088 16.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1f PF01921.13 KNE02357.1 - 0.081 11.5 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) SBF PF01758.11 KNE02358.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.4 1 1 0 1 1 1 0 Sodium Bile acid symporter family zf-C2H2 PF00096.21 KNE02359.1 - 4.1e-05 23.6 21.5 0.00023 21.3 0.4 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNE02359.1 - 0.00028 21.0 22.1 0.0013 18.9 0.7 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 KNE02359.1 - 0.2 11.9 9.2 0.99 9.7 2.7 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KNE02359.1 - 0.68 9.9 3.9 3.4 7.7 1.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KNE02359.1 - 4.6 7.5 11.5 16 5.8 0.3 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding MCM PF00493.18 KNE02360.1 - 7e-135 449.0 0.4 7e-135 449.0 0.2 1.4 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 KNE02360.1 - 5.4e-19 68.8 0.7 4.2e-18 65.9 0.0 2.5 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KNE02360.1 - 3.8e-06 26.2 0.0 2.4e-05 23.6 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KNE02360.1 - 0.012 15.0 0.0 0.027 13.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.6 KNE02360.1 - 0.014 14.9 0.0 0.034 13.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AhpC-TSA PF00578.16 KNE02362.1 - 1.6e-34 118.2 0.1 2.2e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 KNE02362.1 - 7e-14 51.2 0.1 1.2e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 KNE02362.1 - 8.1e-13 48.1 0.0 1.2e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Redoxin Fungal_trans PF04082.13 KNE02363.1 - 2.8e-19 69.0 1.0 5.8e-19 67.9 0.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNE02363.1 - 5.9e-08 32.4 8.7 9.2e-08 31.8 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rad51 PF08423.6 KNE02365.1 - 9.7e-141 467.0 0.0 1.2e-140 466.7 0.0 1.0 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KNE02365.1 - 1.1e-12 47.8 0.0 1.5e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 KNE02365.1 - 5.4e-10 39.2 0.2 1.6e-09 37.7 0.2 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 KNE02365.1 - 1e-09 37.9 0.0 1.4e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 KNE02365.1 - 4.7e-06 25.8 0.2 1.1e-05 24.7 0.1 1.6 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.10 KNE02365.1 - 0.0043 15.9 0.1 0.0084 15.0 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain PAXNEB PF05625.6 KNE02365.1 - 0.0052 15.6 0.0 0.21 10.3 0.0 2.1 2 0 0 2 2 2 1 PAXNEB protein AAA_22 PF13401.1 KNE02365.1 - 0.012 15.7 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3639 PF12341.3 KNE02366.1 - 6e-05 22.9 2.4 0.015 15.2 0.2 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3639) RAB3GAP2_N PF14655.1 KNE02366.1 - 0.017 14.1 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ_3 PF13570.1 KNE02366.1 - 0.076 13.3 1.0 30 5.0 0.0 4.2 5 0 0 5 5 5 0 PQQ-like domain Tom5 PF10642.4 KNE02367.1 - 9e-14 50.8 0.1 1e-13 50.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Acetyltransf_1 PF00583.19 KNE02368.1 - 3.4e-08 33.4 0.0 5.3e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KNE02368.1 - 1.5e-06 27.9 0.0 2.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 KNE02368.1 - 0.0016 18.4 0.0 0.0019 18.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KNE02368.1 - 0.008 16.2 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KNE02368.1 - 0.028 14.5 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain IFRD PF05004.8 KNE02369.1 - 1.4e-11 44.0 2.3 3.2e-11 42.8 0.1 2.1 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) Corona_nucleoca PF00937.13 KNE02369.1 - 1.3 7.8 4.5 2.4 7.0 3.1 1.5 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SUR7 PF06687.7 KNE02370.1 - 1.2e-31 109.9 5.5 1.6e-31 109.5 3.8 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF2721 PF11026.3 KNE02370.1 - 0.0042 16.7 0.3 0.0042 16.7 0.2 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2721) DUF2207 PF09972.4 KNE02370.1 - 0.49 8.9 2.0 0.52 8.8 0.7 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) IncA PF04156.9 KNE02370.1 - 1.4 8.4 0.0 1.4 8.4 0.0 2.8 3 0 0 3 3 3 0 IncA protein TauD PF02668.11 KNE02371.1 - 9.5e-49 166.3 1.1 1.3e-48 165.9 0.7 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Tht1 PF04163.7 KNE02373.1 - 2.6e-22 78.9 19.0 4e-22 78.3 13.2 1.3 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein CobU PF02283.11 KNE02373.1 - 0.049 13.0 4.0 0.082 12.3 0.2 2.5 1 1 1 3 3 3 0 Cobinamide kinase / cobinamide phosphate guanyltransferase NRN1 PF15056.1 KNE02373.1 - 0.056 13.3 0.8 1.6 8.7 0.0 3.4 3 0 0 3 3 3 0 Neuritin protein family Lipoprotein_6 PF01441.14 KNE02373.1 - 0.065 13.0 1.3 0.32 10.8 0.2 2.3 2 0 0 2 2 2 0 Lipoprotein MCPVI PF02993.9 KNE02373.1 - 0.15 12.1 0.1 0.27 11.3 0.1 1.3 1 0 0 1 1 1 0 Minor capsid protein VI Snapin_Pallidin PF14712.1 KNE02373.1 - 2.1 8.7 12.0 1.5 9.1 0.3 3.1 3 0 0 3 3 3 0 Snapin/Pallidin Lipase_3 PF01764.20 KNE02374.1 - 6.7e-31 106.7 0.0 1.1e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KNE02374.1 - 1.2e-05 25.3 0.0 1.6e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KNE02374.1 - 4.8e-05 22.9 0.0 8.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.8 KNE02374.1 - 0.00033 20.3 0.0 0.00056 19.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KNE02374.1 - 0.00038 20.2 0.0 0.0005 19.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KNE02374.1 - 0.025 14.8 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF2974 PF11187.3 KNE02374.1 - 0.03 13.7 0.1 0.45 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PE-PPE PF08237.6 KNE02374.1 - 0.063 12.6 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain DUF4485 PF14846.1 KNE02375.1 - 0.11 12.2 0.1 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) Calcipressin PF04847.7 KNE02376.1 - 3.2e-06 26.8 0.0 4.6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Calcipressin Spore_YhaL PF14147.1 KNE02376.1 - 0.1 12.0 3.6 0.24 10.8 2.5 1.5 1 0 0 1 1 1 0 Sporulation protein YhaL Ribosomal_L1 PF00687.16 KNE02377.1 - 1.2e-41 142.4 2.3 1.8e-41 141.9 1.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Cwf_Cwc_15 PF04889.7 KNE02377.1 - 0.2 11.3 11.6 0.41 10.3 8.0 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PGBA_C PF15437.1 KNE02377.1 - 1 9.5 8.1 2.8 8.1 5.1 2.2 1 1 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal DUF1840 PF08895.6 KNE02377.1 - 2.6 8.0 4.8 0.4 10.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) HSF_DNA-bind PF00447.12 KNE02379.1 - 7.9e-35 119.1 2.5 7.9e-35 119.1 1.7 2.3 2 0 0 2 2 2 1 HSF-type DNA-binding Copper-fist PF00649.13 KNE02380.1 - 6.9e-21 73.1 3.0 1.6e-20 71.9 2.1 1.7 1 0 0 1 1 1 1 Copper fist DNA binding domain tRNA-synt_2c PF01411.14 KNE02381.1 - 3.8e-222 738.4 0.7 4.7e-222 738.1 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KNE02381.1 - 3.6e-18 65.1 0.1 1.4e-17 63.3 0.1 2.1 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 KNE02381.1 - 4.4e-06 26.2 1.7 1.3e-05 24.7 1.2 1.8 1 0 0 1 1 1 1 DHHA1 domain Imm6 PF14434.1 KNE02381.1 - 0.068 12.8 2.1 1 9.0 0.4 2.8 2 0 0 2 2 2 0 Immunity protein Imm6 7kD_coat PF02495.12 KNE02381.1 - 0.18 11.2 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 7kD viral coat protein MoCF_biosynth PF00994.19 KNE02382.1 - 4e-29 100.8 0.0 6.7e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Metallophos PF00149.23 KNE02384.1 - 6.1e-39 133.5 2.7 7.5e-39 133.2 1.8 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ABC2_membrane PF01061.19 KNE02386.1 - 1.9e-71 239.5 63.9 3.7e-43 147.1 13.3 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KNE02386.1 - 3.5e-38 130.9 0.0 7.9e-19 68.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KNE02386.1 - 2.2e-33 114.0 2.2 1.7e-27 95.1 0.0 3.2 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KNE02386.1 - 5.4e-10 39.2 0.0 1.4e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 KNE02386.1 - 3.9e-09 36.0 15.3 3.9e-09 36.0 10.6 3.5 2 2 1 3 3 2 1 ABC-2 family transporter protein DUF258 PF03193.11 KNE02386.1 - 9e-07 28.2 0.1 0.00026 20.2 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KNE02386.1 - 5e-06 26.0 0.0 0.0015 17.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.1 KNE02386.1 - 7e-06 26.2 0.0 0.012 15.6 0.0 3.8 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KNE02386.1 - 1.7e-05 24.2 0.2 0.037 13.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KNE02386.1 - 2e-05 24.6 0.0 0.0036 17.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 KNE02386.1 - 0.0003 20.3 0.6 0.0018 17.7 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 KNE02386.1 - 0.00054 19.8 0.1 1.3 8.9 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 KNE02386.1 - 0.0011 19.1 0.1 0.13 12.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KNE02386.1 - 0.0033 17.7 0.0 0.093 13.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KNE02386.1 - 0.0035 17.2 0.1 0.29 11.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KNE02386.1 - 0.0046 17.7 0.0 0.095 13.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KNE02386.1 - 0.0052 16.0 0.0 1.2 8.3 0.0 3.3 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 KNE02386.1 - 0.0095 15.5 0.9 0.28 10.8 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 KNE02386.1 - 0.01 15.5 0.1 0.24 11.1 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 KNE02386.1 - 0.01 15.3 0.2 2.3 7.6 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family Miro PF08477.8 KNE02386.1 - 0.026 15.0 0.0 12 6.4 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_30 PF13604.1 KNE02386.1 - 0.032 13.7 0.1 0.78 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KNE02386.1 - 0.039 14.2 5.8 0.38 11.0 0.0 3.4 4 0 0 4 4 4 0 AAA domain NACHT PF05729.7 KNE02386.1 - 0.054 13.1 1.9 0.3 10.7 0.1 2.6 2 0 0 2 2 2 0 NACHT domain ABC_ATPase PF09818.4 KNE02386.1 - 0.13 10.8 0.1 0.24 9.9 0.1 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class T2SE PF00437.15 KNE02386.1 - 0.16 10.8 0.2 9.3 5.0 0.1 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein ArgK PF03308.11 KNE02386.1 - 0.35 9.6 0.3 3.9 6.1 0.0 2.1 2 0 0 2 2 2 0 ArgK protein Dynamin_N PF00350.18 KNE02386.1 - 0.57 9.9 1.5 18 5.1 0.0 2.7 3 0 0 3 3 2 0 Dynamin family Cyclin PF08613.6 KNE02387.1 - 2.8e-35 121.9 0.0 3.7e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KNE02387.1 - 1.3e-05 24.7 0.3 1.9e-05 24.1 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF2439 PF10382.4 KNE02388.1 - 2.2e-17 63.0 0.0 4.1e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Ribosomal_L5_C PF00673.16 KNE02389.1 - 2.6e-25 87.9 0.0 4.9e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 ribosomal L5P family C-terminus GLE1 PF07817.8 KNE02390.1 - 1.5e-67 227.2 0.6 1.5e-67 227.2 0.4 2.8 1 1 2 3 3 3 1 GLE1-like protein U79_P34 PF03064.11 KNE02390.1 - 0.59 9.6 17.9 1 8.8 12.4 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Pilt PF15453.1 KNE02390.1 - 3.5 7.2 14.1 5.1 6.6 9.8 1.4 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions CCDC71L PF15374.1 KNE02390.1 - 3.7 6.7 19.4 2.6 7.3 12.3 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 71L HEAT PF02985.17 KNE02391.1 - 3.6e-07 29.7 0.1 0.99 9.6 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 KNE02391.1 - 1.8e-06 28.1 0.0 0.0041 17.3 0.0 4.8 4 1 0 4 4 4 1 HEAT repeats Pkinase PF00069.20 KNE02396.1 - 1.2e-68 231.1 0.0 1.9e-68 230.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE02396.1 - 1.4e-40 139.0 0.0 2.1e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNE02396.1 - 1.1e-08 34.4 0.0 1.9e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KNE02396.1 - 0.0012 17.9 0.0 0.0029 16.7 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KNE02396.1 - 0.019 14.6 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4359 PF14271.1 KNE02396.1 - 0.11 12.9 0.2 0.51 10.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4359) R3H PF01424.17 KNE02398.1 - 7.3e-10 38.4 0.0 1.7e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 R3H domain Fcf1 PF04900.7 KNE02399.1 - 1.3e-31 108.6 0.1 1.3e-31 108.6 0.0 1.7 2 0 0 2 2 2 1 Fcf1 TFIIS_C PF01096.13 KNE02400.1 - 3.1e-19 68.3 6.8 1.3e-17 63.1 1.5 3.1 3 1 1 4 4 4 2 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KNE02400.1 - 2.5e-07 30.2 5.7 3.1e-05 23.5 0.2 3.1 3 0 0 3 3 3 2 RNA polymerases M/15 Kd subunit C1_1 PF00130.17 KNE02400.1 - 0.001 18.7 3.6 0.061 13.0 0.1 2.4 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_2 PF13240.1 KNE02400.1 - 0.0081 15.6 8.1 3 7.4 0.2 3.7 3 1 1 4 4 4 1 zinc-ribbon domain DZR PF12773.2 KNE02400.1 - 0.0089 15.8 7.0 0.54 10.1 0.1 3.0 2 1 0 2 2 2 1 Double zinc ribbon Baculo_LEF5_C PF11792.3 KNE02400.1 - 0.01 15.1 1.2 0.01 15.1 0.9 3.2 3 1 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain Zn-ribbon_8 PF09723.5 KNE02400.1 - 0.011 15.6 10.8 0.4 10.6 0.3 3.4 3 0 0 3 3 3 0 Zinc ribbon domain DUF1922 PF09082.5 KNE02400.1 - 0.03 14.3 0.5 0.078 13.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1922) Phage_Gp111 PF07410.6 KNE02400.1 - 0.044 13.9 0.0 0.051 13.7 0.0 1.1 1 0 0 1 1 1 0 Streptococcus thermophilus bacteriophage Gp111 protein Lar_restr_allev PF14354.1 KNE02400.1 - 0.046 14.0 4.2 0.22 11.8 0.4 2.4 2 0 0 2 2 2 0 Restriction alleviation protein Lar Terminase_GpA PF05876.7 KNE02400.1 - 0.054 11.8 0.6 0.075 11.3 0.4 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Zn_Tnp_IS1595 PF12760.2 KNE02400.1 - 0.06 13.1 5.3 0.93 9.3 1.6 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain DUF3716 PF12511.3 KNE02400.1 - 0.079 12.5 2.0 0.28 10.8 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) TF_Zn_Ribbon PF08271.7 KNE02400.1 - 0.088 12.1 12.9 0.097 12.0 1.7 3.4 2 2 1 3 3 3 0 TFIIB zinc-binding Elf1 PF05129.8 KNE02400.1 - 0.14 11.8 5.5 0.59 9.8 0.3 2.5 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zinc_ribbon_6 PF14599.1 KNE02400.1 - 0.15 11.8 3.7 0.65 9.8 0.2 2.8 3 0 0 3 3 3 0 Zinc-ribbon zf-ribbon_3 PF13248.1 KNE02400.1 - 0.23 10.7 10.1 1.7 7.9 0.1 3.5 3 1 0 3 3 3 0 zinc-ribbon domain Stc1 PF12898.2 KNE02400.1 - 0.26 11.3 5.1 0.55 10.3 0.1 2.2 1 1 1 2 2 2 0 Stc1 domain YhfH PF14149.1 KNE02400.1 - 0.37 10.6 7.3 17 5.3 0.6 3.3 3 0 0 3 3 3 0 YhfH-like protein RRN7 PF11781.3 KNE02400.1 - 0.44 10.0 6.5 45 3.6 0.7 4.1 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-HYPF PF07503.7 KNE02400.1 - 0.46 9.9 0.2 0.46 9.9 0.1 3.2 4 0 0 4 4 4 0 HypF finger zf-C2H2_6 PF13912.1 KNE02400.1 - 0.83 9.6 5.3 11 6.0 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2387 PF09526.5 KNE02400.1 - 0.96 9.4 9.6 2.2 8.2 0.4 3.3 2 2 1 3 3 3 0 Probable metal-binding protein (DUF2387) IBR PF01485.16 KNE02400.1 - 1.4 8.8 8.1 11 6.0 0.1 3.1 2 1 0 2 2 2 0 IBR domain DUF2072 PF09845.4 KNE02400.1 - 1.6 8.6 6.2 3.7 7.5 0.1 2.9 1 1 1 3 3 3 0 Zn-ribbon containing protein (DUF2072) Churchill PF06573.6 KNE02400.1 - 2 8.4 6.3 2.6 8.0 2.1 2.3 1 1 1 2 2 2 0 Churchill protein GATA PF00320.22 KNE02400.1 - 3.3 7.1 6.0 0.61 9.4 1.0 2.2 2 0 0 2 2 2 0 GATA zinc finger Ogr_Delta PF04606.7 KNE02400.1 - 3.8 7.2 8.7 0.25 11.0 2.3 2.0 2 0 0 2 2 1 0 Ogr/Delta-like zinc finger zf-P11 PF03854.9 KNE02400.1 - 3.9 7.0 8.3 0.12 11.8 0.6 2.2 3 0 0 3 3 2 0 P-11 zinc finger DUF951 PF06107.6 KNE02400.1 - 4.4 6.8 5.2 1.3 8.5 0.1 2.5 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF951) OrfB_Zn_ribbon PF07282.6 KNE02400.1 - 4.8 6.9 7.5 10 5.8 1.9 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-AN1 PF01428.11 KNE02400.1 - 5.7 6.9 7.6 26 4.7 0.1 3.2 3 1 0 3 3 3 0 AN1-like Zinc finger DNA_RNApol_7kD PF03604.8 KNE02400.1 - 6.9 6.2 12.7 5 6.6 0.7 3.4 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.1 KNE02400.1 - 7.2 6.3 10.1 7.6 6.3 0.1 3.3 4 0 0 4 4 3 0 zinc-ribbon domain zf-RING_5 PF14634.1 KNE02400.1 - 8.8 6.1 10.0 0.91 9.2 0.4 2.9 2 1 0 2 2 2 0 zinc-RING finger domain HEAT_2 PF13646.1 KNE02401.1 - 2.2e-32 111.1 2.0 4.5e-16 58.8 0.0 3.6 2 2 1 3 3 3 2 HEAT repeats HEAT_PBS PF03130.11 KNE02401.1 - 2.7e-21 73.8 0.1 3.3e-05 23.9 0.0 7.3 8 0 0 8 8 8 4 PBS lyase HEAT-like repeat HEAT PF02985.17 KNE02401.1 - 1.7e-12 46.2 1.1 0.33 11.1 0.1 7.3 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 KNE02401.1 - 1.9e-10 40.9 1.3 0.05 14.1 0.0 5.7 4 2 1 6 6 6 3 HEAT-like repeat Arm PF00514.18 KNE02401.1 - 0.02 14.7 0.2 1.4 8.8 0.0 3.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 KNE02401.1 - 0.14 12.0 0.7 23 4.7 0.0 3.6 3 2 2 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Cpn60_TCP1 PF00118.19 KNE02402.1 - 4.9e-143 477.2 8.8 5.7e-143 477.0 6.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Hydrolase_like2 PF13246.1 KNE02402.1 - 0.072 13.0 0.0 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Actin PF00022.14 KNE02403.1 - 3.2e-91 305.6 0.0 6.8e-91 304.6 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KNE02403.1 - 0.0045 15.6 0.0 0.24 9.9 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FAT PF02259.18 KNE02404.1 - 4.1e-141 470.0 2.6 4.1e-141 470.0 1.8 2.6 3 0 0 3 3 3 1 FAT domain DUF3385 PF11865.3 KNE02404.1 - 4.6e-64 215.1 7.4 2.5e-61 206.2 0.3 5.2 4 1 0 4 4 4 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 KNE02404.1 - 5.2e-61 206.1 0.2 1.3e-60 204.8 0.2 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 KNE02404.1 - 3.3e-42 142.6 7.1 1.7e-41 140.3 0.7 3.7 3 0 0 3 3 3 1 Rapamycin binding domain FATC PF02260.15 KNE02404.1 - 8.1e-17 60.3 0.1 8.1e-17 60.3 0.1 2.4 3 0 0 3 3 3 1 FATC domain HEAT_2 PF13646.1 KNE02404.1 - 4.4e-15 55.7 6.6 0.0052 17.0 0.3 9.5 6 3 4 10 10 8 3 HEAT repeats HEAT PF02985.17 KNE02404.1 - 4.1e-12 45.0 3.8 0.028 14.4 0.0 8.2 8 0 0 8 8 7 2 HEAT repeat HEAT_EZ PF13513.1 KNE02404.1 - 7.9e-06 26.2 22.1 0.0003 21.2 0.1 10.1 9 2 5 14 14 13 3 HEAT-like repeat TPR_16 PF13432.1 KNE02404.1 - 0.00018 22.0 0.7 0.13 12.9 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KNE02404.1 - 0.00026 21.2 0.1 3.7 7.9 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat Cnd3 PF12719.2 KNE02404.1 - 0.00049 19.1 1.6 0.025 13.5 0.1 3.9 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain TPR_14 PF13428.1 KNE02404.1 - 0.0039 17.7 0.7 2.7 8.8 0.0 4.7 3 1 1 4 4 3 1 Tetratricopeptide repeat Vac14_Fab1_bd PF12755.2 KNE02404.1 - 0.1 13.0 8.3 10 6.6 0.0 6.0 5 3 1 6 6 5 0 Vacuolar 14 Fab1-binding region RTC PF01137.16 KNE02405.1 - 2.4e-53 180.2 0.0 2.7e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 KNE02405.1 - 9.7e-32 109.0 0.0 1.5e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain CPSase_L_D3 PF02787.14 KNE02405.1 - 0.081 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain TAF4 PF05236.9 KNE02406.1 - 7e-68 228.7 0.1 1e-67 228.2 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family SAGA-Tad1 PF12767.2 KNE02406.1 - 0.21 11.2 0.0 0.21 11.2 0.0 3.0 3 0 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit Cnd1 PF12717.2 KNE02407.1 - 2.5e-47 160.9 1.7 2.5e-47 160.9 1.2 4.2 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 KNE02407.1 - 7.3e-39 133.1 1.5 3.6e-38 130.8 0.4 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 KNE02407.1 - 1.9e-08 34.4 0.0 0.066 13.4 0.0 4.7 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.17 KNE02407.1 - 2.4e-05 24.0 0.8 6.8 7.0 0.0 5.8 5 0 0 5 5 5 2 HEAT repeat Cnd3 PF12719.2 KNE02407.1 - 9.8e-05 21.4 10.6 0.004 16.1 1.7 4.9 2 2 3 5 5 5 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.1 KNE02407.1 - 0.00049 20.5 0.0 6.9 7.2 0.0 4.7 4 1 1 5 5 5 2 HEAT-like repeat MBOAT PF03062.14 KNE02408.1 - 2.1e-55 188.0 4.4 2.1e-55 188.0 3.1 1.6 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MutS_IV PF05190.13 KNE02408.1 - 0.038 14.1 0.6 0.038 14.1 0.4 2.0 2 0 0 2 2 2 0 MutS family domain IV Ferrochelatase PF00762.14 KNE02409.1 - 5.5e-88 294.9 0.0 6.4e-88 294.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase RE_EcoO109I PF14511.1 KNE02409.1 - 0.0041 16.5 0.0 2.8 7.2 0.0 2.4 2 0 0 2 2 2 2 Type II restriction endonuclease EcoO109I Med4 PF10018.4 KNE02411.1 - 1.8e-31 109.0 3.6 1.8e-31 109.0 2.5 1.4 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Kinesin-relat_1 PF12711.2 KNE02411.1 - 0.033 14.5 1.9 0.033 14.5 1.3 1.8 2 0 0 2 2 2 0 Kinesin motor Phage_lysis PF03245.8 KNE02411.1 - 0.069 13.1 0.7 0.069 13.1 0.5 1.9 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein WD40_alt PF14077.1 KNE02411.1 - 1.9 8.1 5.2 0.68 9.6 0.6 2.4 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF4187 PF13821.1 KNE02412.1 - 1.2e-14 53.5 1.5 1.2e-14 53.5 1.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.18 KNE02412.1 - 5.3e-08 32.5 0.1 9e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KNE02412.1 - 0.0017 18.1 0.6 0.0063 16.3 0.0 2.1 2 0 0 2 2 2 1 DExH-box splicing factor binding site RRM_1 PF00076.17 KNE02413.1 - 7.5e-34 115.1 0.0 5.6e-16 57.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNE02413.1 - 6.1e-26 90.2 0.0 3e-08 33.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNE02413.1 - 2.4e-15 56.1 0.3 0.00015 21.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KNE02413.1 - 0.00048 19.8 0.0 0.007 16.1 0.0 2.6 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KNE02413.1 - 0.017 14.9 0.0 4 7.3 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif NDUF_B8 PF05821.6 KNE02415.1 - 3.4e-13 49.6 1.7 4.6e-13 49.2 1.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.18 KNE02416.1 - 1.8e-75 253.5 0.4 1.8e-75 253.5 0.3 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KNE02416.1 - 2.3e-14 52.9 0.0 9e-14 51.1 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.8 KNE02416.1 - 3.1e-11 42.8 5.9 3.1e-11 42.8 4.1 3.5 3 0 0 3 3 3 2 HSA DEAD PF00270.24 KNE02416.1 - 1.2e-05 24.9 0.0 3.5e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase V-ATPase_G PF03179.10 KNE02417.1 - 1.8e-29 102.0 19.6 2e-29 101.9 13.6 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 KNE02417.1 - 0.0008 19.2 10.4 0.0008 19.2 7.2 2.0 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) Mst1_SARAH PF11629.3 KNE02417.1 - 0.0078 16.0 0.4 0.0078 16.0 0.3 2.5 2 1 1 3 3 3 1 C terminal SARAH domain of Mst1 AAA-ATPase_like PF09820.4 KNE02417.1 - 0.027 13.6 5.9 0.029 13.5 4.1 1.1 1 0 0 1 1 1 0 Predicted AAA-ATPase Transposase_22 PF02994.9 KNE02417.1 - 0.12 10.8 11.4 0.14 10.6 7.9 1.2 1 0 0 1 1 1 0 L1 transposable element GNT-I PF03071.10 KNE02417.1 - 0.14 10.6 4.5 0.17 10.4 3.1 1.0 1 0 0 1 1 1 0 GNT-I family Choline_kinase PF01633.15 KNE02417.1 - 0.2 11.2 6.2 0.23 11.0 4.3 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase OmpH PF03938.9 KNE02417.1 - 0.24 11.3 18.7 0.32 10.9 13.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HrpE PF06188.7 KNE02417.1 - 0.24 11.1 7.1 0.39 10.4 4.9 1.3 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E DUF2362 PF10154.4 KNE02417.1 - 0.31 9.6 10.3 0.33 9.5 7.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Exonuc_VII_L PF02601.10 KNE02417.1 - 0.34 10.0 8.5 0.39 9.8 5.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit GBP_C PF02841.9 KNE02417.1 - 0.35 10.0 16.4 0.38 9.9 11.4 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain IncA PF04156.9 KNE02417.1 - 0.35 10.4 13.2 0.43 10.1 9.2 1.2 1 0 0 1 1 1 0 IncA protein DUF2203 PF09969.4 KNE02417.1 - 0.41 10.8 6.6 0.59 10.3 4.5 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Prominin PF05478.6 KNE02417.1 - 0.42 8.0 5.3 0.5 7.8 3.7 1.1 1 0 0 1 1 1 0 Prominin Mob_Pre PF01076.14 KNE02417.1 - 0.45 10.1 12.4 0.61 9.7 8.6 1.2 1 0 0 1 1 1 0 Plasmid recombination enzyme DUF3337 PF11816.3 KNE02417.1 - 0.52 9.6 8.9 0.56 9.5 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Peptidase_S46 PF10459.4 KNE02417.1 - 0.55 8.5 9.8 0.63 8.3 6.8 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF3391 PF11871.3 KNE02417.1 - 0.77 9.9 10.8 1.7 8.8 7.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) AAA_13 PF13166.1 KNE02417.1 - 0.83 8.0 16.0 0.91 7.9 11.1 1.0 1 0 0 1 1 1 0 AAA domain DUF3552 PF12072.3 KNE02417.1 - 0.85 8.7 23.1 1.4 8.0 16.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) ArfGap PF01412.13 KNE02417.1 - 1.4 8.7 7.7 1.7 8.4 5.4 1.2 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf DUF2894 PF11445.3 KNE02417.1 - 1.4 9.1 6.9 1.6 8.9 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) MRP-S27 PF10037.4 KNE02417.1 - 2.1 7.1 11.9 2.2 7.0 8.2 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF2317 PF10079.4 KNE02417.1 - 2.3 6.7 13.5 2.5 6.6 9.4 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) tRNA-synt_His PF13393.1 KNE02417.1 - 2.5 7.0 5.8 2.8 6.9 4.0 1.0 1 0 0 1 1 1 0 Histidyl-tRNA synthetase DUF342 PF03961.8 KNE02417.1 - 2.9 6.1 13.0 3.5 5.9 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PEPcase_2 PF14010.1 KNE02417.1 - 3.5 5.8 9.7 4.3 5.5 6.7 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase HSP70 PF00012.15 KNE02417.1 - 3.6 5.3 14.3 4 5.2 9.9 1.0 1 0 0 1 1 1 0 Hsp70 protein Membralin PF09746.4 KNE02417.1 - 3.6 6.5 5.5 3.9 6.4 3.8 1.0 1 0 0 1 1 1 0 Tumour-associated protein Atg14 PF10186.4 KNE02417.1 - 3.6 6.4 13.0 4.8 6.0 9.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF883 PF05957.8 KNE02417.1 - 4.1 7.8 11.5 9.4 6.7 3.1 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) PEP-utilisers_N PF05524.8 KNE02417.1 - 4.5 7.0 8.6 2.2e+02 1.6 6.0 2.2 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal GA PF01468.12 KNE02417.1 - 5.3 7.2 14.0 0.2 11.8 3.7 2.9 2 2 1 3 3 3 0 GA module Gti1_Pac2 PF09729.4 KNE02417.1 - 5.5 6.8 7.5 7 6.4 5.2 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family vATP-synt_E PF01991.13 KNE02417.1 - 5.8 6.1 22.7 22 4.2 15.8 1.7 1 1 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Striatin PF08232.7 KNE02417.1 - 6 7.1 15.9 6.6 7.0 11.0 1.0 1 0 0 1 1 1 0 Striatin family APG6 PF04111.7 KNE02417.1 - 6 5.8 17.3 7.2 5.5 12.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 KfrA_N PF11740.3 KNE02417.1 - 6.2 7.2 10.0 2.9 8.3 2.5 2.1 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Mitofilin PF09731.4 KNE02417.1 - 6.2 5.3 20.9 7.2 5.1 14.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein YlqD PF11068.3 KNE02417.1 - 7 6.7 17.4 7.5 6.6 11.5 1.4 1 1 0 1 1 1 0 YlqD protein SAPS PF04499.10 KNE02417.1 - 8.7 4.8 10.7 9 4.7 7.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4407 PF14362.1 KNE02417.1 - 8.9 5.1 11.8 13 4.6 8.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Aldedh PF00171.17 KNE02418.1 - 2e-121 405.5 0.0 2.5e-121 405.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Tcf25 PF04910.9 KNE02419.1 - 1.1e-87 294.2 0.3 1.8e-87 293.6 0.2 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 DUF4011 PF13195.1 KNE02419.1 - 0.058 13.4 2.9 0.12 12.3 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Acetyltransf_6 PF13480.1 KNE02419.1 - 0.064 13.2 0.4 0.25 11.2 0.3 2.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pox_Ag35 PF03286.9 KNE02419.1 - 0.93 8.9 12.8 2.2 7.7 8.9 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NARP1 PF12569.3 KNE02419.1 - 8.7 4.9 11.7 20 3.7 7.7 1.7 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 SBDS PF01172.13 KNE02420.1 - 2.2e-20 72.2 0.1 2.4e-20 72.1 0.1 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Arf PF00025.16 KNE02422.1 - 3.1e-48 163.3 0.0 3.5e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KNE02422.1 - 1.7e-08 33.5 0.0 2.9e-08 32.8 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Ras PF00071.17 KNE02422.1 - 0.0002 20.7 0.0 0.00021 20.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNE02422.1 - 0.00029 21.3 0.0 0.00039 20.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KNE02422.1 - 0.00074 18.7 0.0 0.00099 18.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FMO-like PF00743.14 KNE02423.1 - 6.7e-30 103.7 0.0 5.3e-11 41.4 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KNE02423.1 - 7.7e-16 58.7 0.0 2.8e-15 56.9 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KNE02423.1 - 1.3e-12 47.9 0.0 6.1e-11 42.5 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KNE02423.1 - 2.3e-11 43.7 0.0 5.3e-10 39.2 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KNE02423.1 - 1.6e-08 34.4 0.1 4.8e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KNE02423.1 - 4.3e-07 29.1 0.1 0.00012 21.0 0.0 3.4 2 1 2 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KNE02423.1 - 1.1e-06 27.8 0.0 0.016 14.1 0.0 3.0 2 1 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 KNE02423.1 - 2.4e-05 23.5 0.5 0.0015 17.6 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 KNE02423.1 - 4.8e-05 23.6 1.1 0.59 10.5 0.0 3.7 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KNE02423.1 - 9.4e-05 21.0 0.0 0.015 13.7 0.0 2.4 2 1 0 2 2 2 2 HI0933-like protein Amino_oxidase PF01593.19 KNE02423.1 - 0.0031 16.6 0.0 1.6 7.7 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 KNE02423.1 - 0.0033 16.5 0.0 0.0079 15.3 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase She9_MDM33 PF05546.6 KNE02423.1 - 0.0098 15.4 0.6 0.07 12.6 0.1 2.1 2 0 0 2 2 2 1 She9 / Mdm33 family FAD_binding_2 PF00890.19 KNE02423.1 - 0.036 12.9 0.1 0.26 10.1 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain Adenylsucc_synt PF00709.16 KNE02423.1 - 0.056 12.0 0.0 0.1 11.2 0.0 1.3 1 0 0 1 1 1 0 Adenylosuccinate synthetase FAD_binding_3 PF01494.14 KNE02423.1 - 0.14 11.2 0.2 0.25 10.3 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 KNE02423.1 - 0.22 10.3 0.1 0.92 8.2 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF1910 PF08928.5 KNE02424.1 - 0.091 12.7 0.0 0.091 12.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) APH PF01636.18 KNE02427.1 - 1.8e-09 37.7 0.0 1.7e-08 34.4 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KNE02427.1 - 0.00063 18.8 0.0 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 Fructosamine kinase Sedlin_N PF04628.8 KNE02428.1 - 2.7e-41 140.5 0.0 3.3e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 KNE02428.1 - 0.0007 19.3 1.6 0.0019 17.8 0.3 2.3 2 1 0 2 2 2 1 Sybindin-like family NurA PF09376.5 KNE02429.1 - 0.17 11.3 5.6 3.7 6.9 3.9 2.2 1 1 0 1 1 1 0 NurA domain SSXT PF05030.7 KNE02430.1 - 0.029 13.9 0.1 0.031 13.8 0.1 1.1 1 0 0 1 1 1 0 SSXT protein (N-terminal region) Dynactin_p22 PF07426.6 KNE02430.1 - 0.11 11.7 0.1 0.11 11.7 0.1 1.0 1 0 0 1 1 1 0 Dynactin subunit p22 ARL2_Bind_BART PF11527.3 KNE02430.1 - 0.12 12.2 0.2 0.12 12.1 0.1 1.0 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART Paramyxo_ncap PF00973.14 KNE02431.1 - 1.2 7.7 5.5 2 7.0 3.8 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PITH PF06201.8 KNE02432.1 - 5.2e-28 97.7 0.7 8.1e-28 97.1 0.5 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 KNE02432.1 - 1.1e-23 82.8 0.1 2.5e-23 81.7 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KNE02432.1 - 1.8e-10 40.9 0.1 1e-09 38.5 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KNE02432.1 - 7.5e-08 32.3 0.1 3.5e-06 27.0 0.0 2.6 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KNE02432.1 - 2.4e-05 24.2 0.1 5.4e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KNE02432.1 - 5.2e-05 22.8 0.0 0.0001 21.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 KNE02432.1 - 0.021 14.6 0.0 0.052 13.3 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin domain TrbC_Ftype PF09673.5 KNE02432.1 - 0.025 14.1 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein AhpC-TSA PF00578.16 KNE02432.1 - 0.03 14.0 0.1 0.13 11.9 0.0 2.0 1 1 0 1 1 1 0 AhpC/TSA family Glutaredoxin PF00462.19 KNE02432.1 - 0.078 12.9 0.2 0.47 10.4 0.0 2.3 2 0 0 2 2 2 0 Glutaredoxin LETM1 PF07766.8 KNE02433.1 - 2.3e-96 321.9 1.9 3.9e-96 321.2 1.3 1.3 1 0 0 1 1 1 1 LETM1-like protein dUTPase PF00692.14 KNE02434.1 - 5.9e-45 151.8 0.0 6.8e-45 151.6 0.0 1.0 1 0 0 1 1 1 1 dUTPase COXG PF06240.8 KNE02434.1 - 0.11 12.2 0.1 0.39 10.3 0.0 1.8 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit G (CoxG) CAF1A PF12253.3 KNE02437.1 - 4.2e-23 81.2 8.8 4.2e-23 81.2 6.1 3.3 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 KNE02437.1 - 4.8e-10 39.1 86.3 1.7e-08 34.1 59.8 2.4 1 1 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Tn7_Tnp_TnsA_C PF08721.6 KNE02437.1 - 3.5 7.7 9.5 1.1 9.3 0.1 3.7 3 1 1 4 4 4 0 TnsA endonuclease C terminal Borrelia_P83 PF05262.6 KNE02437.1 - 5.4 5.1 40.6 12 4.0 28.1 1.6 1 0 0 1 1 1 0 Borrelia P83/100 protein Slx4 PF09494.5 KNE02438.1 - 5.5e-11 42.0 0.0 1.2e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Slx4 endonuclease OSCP PF00213.13 KNE02438.1 - 0.33 10.8 5.9 1.2 8.9 0.3 3.1 1 1 2 3 3 3 0 ATP synthase delta (OSCP) subunit DUF885 PF05960.6 KNE02438.1 - 0.48 9.5 3.1 0.91 8.6 1.8 1.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF885) FixQ PF05545.6 KNE02439.1 - 0.044 13.4 0.3 0.082 12.5 0.2 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ JmjC PF02373.17 KNE02440.1 - 2.8e-40 137.1 2.1 2.8e-40 137.1 1.5 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.12 KNE02440.1 - 9.5e-17 60.2 2.1 2e-16 59.2 1.4 1.6 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.1 KNE02440.1 - 2.5e-10 40.3 9.9 2.6e-10 40.3 4.6 2.3 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KNE02440.1 - 9.3e-10 38.4 7.3 1.2e-09 38.1 3.4 2.2 2 0 0 2 2 2 1 PHD-zinc-finger like domain Rad17 PF03215.10 KNE02441.1 - 5.8e-56 190.2 1.1 7e-45 153.6 0.0 2.2 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 KNE02441.1 - 0.006 17.3 0.1 0.035 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KNE02441.1 - 0.061 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KNE02441.1 - 0.062 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 KNE02441.1 - 0.067 13.1 0.0 0.22 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KNE02441.1 - 0.088 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Glutaredoxin PF00462.19 KNE02442.1 - 5.9e-20 71.0 0.0 8.9e-18 64.0 0.0 2.9 3 0 0 3 3 3 1 Glutaredoxin Thioredoxin PF00085.15 KNE02442.1 - 3.8e-14 52.2 0.0 8.2e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KNE02442.1 - 5.8e-06 26.3 0.0 0.0002 21.4 0.0 2.6 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KNE02442.1 - 0.001 18.6 0.0 0.0094 15.5 0.0 2.1 2 1 0 2 2 2 1 Thioredoxin ArsC PF03960.10 KNE02442.1 - 0.0011 18.9 0.0 0.063 13.3 0.0 2.7 3 0 0 3 3 3 1 ArsC family Ribosomal_60s PF00428.14 KNE02442.1 - 0.0021 18.3 1.7 0.0043 17.4 1.2 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein Thioredoxin_2 PF13098.1 KNE02442.1 - 0.0039 17.3 0.0 0.083 13.0 0.0 3.0 1 1 1 2 2 2 1 Thioredoxin-like domain Phosducin PF02114.11 KNE02442.1 - 0.0093 14.7 0.0 0.013 14.2 0.0 1.2 1 0 0 1 1 1 1 Phosducin GST_N_3 PF13417.1 KNE02442.1 - 0.02 15.1 0.0 0.058 13.6 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Thioredoxin_7 PF13899.1 KNE02442.1 - 0.065 13.2 0.0 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like DUF1345 PF07077.6 KNE02447.1 - 0.0087 15.6 0.0 0.0097 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1345) DUF2951 PF11166.3 KNE02447.1 - 0.01 15.6 0.2 0.01 15.6 0.1 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF2951) DUF1620 PF07774.8 KNE02447.1 - 0.013 14.7 0.7 0.018 14.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1620) Baculo_11_kDa PF06143.6 KNE02447.1 - 0.019 14.3 0.4 0.52 9.7 0.0 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family Vpu PF00558.14 KNE02447.1 - 0.024 14.1 0.1 0.024 14.1 0.1 2.4 2 1 1 3 3 3 0 Vpu protein DUF2434 PF10361.4 KNE02447.1 - 0.033 13.2 0.5 1.8 7.5 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2434) DUF3270 PF11674.3 KNE02447.1 - 0.045 13.7 2.0 0.1 12.6 1.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3270) DUF4191 PF13829.1 KNE02447.1 - 0.058 12.4 0.2 0.066 12.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF2207 PF09972.4 KNE02447.1 - 0.07 11.7 0.1 0.082 11.4 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TRAP-gamma PF07074.7 KNE02447.1 - 0.11 12.0 1.7 0.15 11.6 0.2 1.7 1 1 1 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) OppC_N PF12911.2 KNE02447.1 - 0.22 10.9 1.6 1.3 8.4 1.0 2.0 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF4199 PF13858.1 KNE02447.1 - 0.51 10.2 5.4 0.54 10.1 3.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) DUF4212 PF13937.1 KNE02447.1 - 1.2 9.1 4.7 8.7 6.4 0.1 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4212) Orthoreo_P10 PF07204.6 KNE02447.1 - 2.8 7.7 4.4 3.3 7.5 1.9 1.8 1 1 1 2 2 2 0 Orthoreovirus membrane fusion protein p10 DUF1201 PF06716.6 KNE02447.1 - 4.2 7.2 12.7 0.075 12.8 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1201) DUF4149 PF13664.1 KNE02448.1 - 1.9e-22 79.2 1.1 3.6e-21 75.1 0.1 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4149) MutS_V PF00488.16 KNE02449.1 - 5.4e-75 251.8 0.0 8.7e-75 251.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KNE02449.1 - 4e-44 150.8 0.1 7.2e-44 150.0 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KNE02449.1 - 4.5e-32 110.4 0.2 2.7e-31 107.9 0.0 2.2 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 KNE02449.1 - 4.2e-12 46.2 0.1 9.8e-12 45.1 0.1 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 KNE02449.1 - 1.9e-11 43.9 1.2 6.6e-11 42.2 0.3 2.4 3 0 0 3 3 3 1 MutS family domain IV AAA_29 PF13555.1 KNE02449.1 - 0.0063 16.0 0.1 0.019 14.4 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 KNE02449.1 - 0.066 13.1 0.1 0.066 13.1 0.1 3.5 3 2 0 3 3 3 0 AAA domain AAA_23 PF13476.1 KNE02449.1 - 0.14 12.5 0.1 0.14 12.5 0.0 3.1 4 0 0 4 4 4 0 AAA domain XisI PF08869.6 KNE02450.1 - 0.12 12.4 0.2 0.57 10.3 0.0 1.9 2 0 0 2 2 2 0 XisI protein NTP_transferase PF00483.18 KNE02451.1 - 9e-22 77.5 0.0 1.6e-20 73.4 0.0 2.5 2 1 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 KNE02451.1 - 3.9e-08 32.4 11.5 0.00011 21.5 0.2 4.0 2 1 2 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KNE02451.1 - 0.0049 16.3 7.7 0.056 13.0 2.9 2.7 1 1 1 2 2 2 2 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 KNE02451.1 - 0.086 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain RNase_T PF00929.19 KNE02452.1 - 4.9e-15 56.1 0.0 9.7e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 KNE02452.1 - 1.8e-05 24.2 0.0 7.2e-05 22.3 0.0 2.0 1 1 0 1 1 1 1 3'-5' exonuclease CHORD PF04968.7 KNE02452.1 - 0.0099 16.1 0.4 0.022 14.9 0.3 1.5 1 0 0 1 1 1 1 CHORD Ank_2 PF12796.2 KNE02453.1 - 3.8e-33 113.6 0.1 1.3e-15 57.4 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 KNE02453.1 - 3.5e-30 102.2 1.8 8.2e-07 28.5 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat zf-DHHC PF01529.15 KNE02453.1 - 1.9e-26 92.5 5.6 1.9e-26 92.5 3.9 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.1 KNE02453.1 - 8.7e-26 89.3 1.8 4.2e-07 30.0 0.1 4.9 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNE02453.1 - 1.6e-25 86.5 1.6 4.1e-05 23.4 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 KNE02453.1 - 5.7e-23 80.8 0.3 1.7e-08 34.7 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) DUF4112 PF13430.1 KNE02454.1 - 5.5e-28 96.9 0.1 7.6e-28 96.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF2360 PF10152.4 KNE02455.1 - 0.016 15.5 0.5 0.016 15.5 0.4 1.9 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) NinE PF05322.6 KNE02457.1 - 0.014 15.1 0.1 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 NINE Protein CTP_transf_2 PF01467.21 KNE02458.1 - 9.4e-06 25.7 0.2 5.2e-05 23.3 0.1 2.1 1 1 0 1 1 1 1 Cytidylyltransferase Recep_L_domain PF01030.19 KNE02459.1 - 8.3e-10 38.6 7.0 0.00061 19.7 0.1 4.6 1 1 2 4 4 4 4 Receptor L domain PP2C PF00481.16 KNE02462.1 - 3.4e-11 43.0 1.1 0.00013 21.4 0.3 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 KNE02462.1 - 4.1e-09 36.4 0.0 8.1e-09 35.4 0.0 1.4 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KNE02462.1 - 4.7e-08 32.6 0.0 8.1e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Oxysterol_BP PF01237.13 KNE02463.1 - 3.9 5.8 5.8 4.5 5.6 4.0 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein EPSP_synthase PF00275.15 KNE02464.1 - 4.5e-129 430.5 0.2 7.1e-129 429.9 0.2 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 KNE02464.1 - 8.1e-99 329.7 0.2 2.7e-98 328.0 0.1 1.9 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 KNE02464.1 - 3.1e-52 177.4 2.6 6.3e-52 176.4 0.0 3.0 5 0 0 5 5 5 1 Type I 3-dehydroquinase SKI PF01202.17 KNE02464.1 - 3.1e-38 131.1 0.3 1.8e-37 128.6 0.0 2.4 3 0 0 3 3 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 KNE02464.1 - 3.7e-21 74.9 0.0 1.3e-20 73.2 0.0 2.0 2 0 0 2 2 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KNE02464.1 - 7.2e-16 58.5 0.0 2.5e-15 56.7 0.0 1.9 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 KNE02464.1 - 8.6e-10 38.3 0.4 4.3e-09 36.0 0.1 2.3 2 1 0 2 2 2 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 KNE02464.1 - 4.6e-08 33.9 0.1 1.5e-07 32.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain Fe-ADH PF00465.14 KNE02464.1 - 7.5e-05 21.5 1.7 0.00063 18.4 1.2 2.3 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_33 PF13671.1 KNE02464.1 - 0.0039 17.0 0.0 0.016 15.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain ETF PF01012.16 KNE02464.1 - 0.018 14.7 0.0 8 6.1 0.0 2.7 2 0 0 2 2 2 0 Electron transfer flavoprotein domain AAA_18 PF13238.1 KNE02464.1 - 0.024 14.9 0.4 0.095 13.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain Pyr_redox_3 PF13738.1 KNE02464.1 - 0.028 14.4 0.0 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GARS_N PF02844.10 KNE02464.1 - 0.037 14.4 0.1 0.24 11.8 0.1 2.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain CoaE PF01121.15 KNE02464.1 - 0.041 13.2 0.0 0.089 12.1 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase Pyr_redox PF00070.22 KNE02464.1 - 0.32 11.4 5.0 1.6 9.1 0.0 3.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase PolyA_pol PF01743.15 KNE02466.1 - 3.1e-30 104.9 0.0 6.7e-30 103.8 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 KNE02466.1 - 4.8e-10 38.8 0.0 1.1e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 KNE02466.1 - 0.0017 18.1 0.0 0.0045 16.8 0.0 1.7 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative ArfGap PF01412.13 KNE02467.1 - 5.4e-29 100.3 1.6 5.4e-29 100.3 1.1 2.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 KNE02467.1 - 6.2e-12 45.6 0.8 5.4e-11 42.6 0.0 2.8 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 KNE02467.1 - 5.4e-05 23.3 0.1 0.00026 21.1 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.1 KNE02467.1 - 0.00017 21.6 0.0 0.00047 20.2 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain DUF2205 PF10224.4 KNE02467.1 - 0.051 13.1 1.8 8.5 6.0 0.1 2.7 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) MAT1 PF06391.8 KNE02468.1 - 7.3e-42 143.2 29.5 9e-42 142.9 20.4 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 DUF3552 PF12072.3 KNE02468.1 - 2.7 7.1 30.7 0.96 8.6 18.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Prominin PF05478.6 KNE02468.1 - 3.3 5.1 9.0 3.5 5.0 6.2 1.1 1 0 0 1 1 1 0 Prominin LMBR1 PF04791.11 KNE02468.1 - 4.3 5.7 5.6 4.8 5.6 3.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PaaSYMP PF14738.1 KNE02469.1 - 0.0081 15.8 4.2 0.013 15.2 2.9 1.3 1 0 0 1 1 1 1 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 Cgr1 PF03879.9 KNE02469.1 - 0.012 15.7 7.4 0.02 15.0 5.2 1.3 1 0 0 1 1 1 0 Cgr1 family CGI-121 PF08617.5 KNE02470.1 - 2e-33 115.3 1.8 2.4e-33 115.0 1.2 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Blo-t-5 PF11642.3 KNE02470.1 - 0.037 13.7 0.1 0.054 13.2 0.1 1.3 1 0 0 1 1 1 0 Mite allergen Blo t 5 XPG_I PF00867.13 KNE02471.1 - 3.6e-24 84.6 0.0 1.1e-23 83.0 0.0 1.9 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KNE02471.1 - 1.6e-22 79.6 0.0 9.5e-22 77.1 0.0 2.3 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 KNE02471.1 - 4.6e-07 29.9 0.1 1.2e-05 25.5 0.0 2.9 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.2 KNE02471.1 - 9.5e-06 25.4 0.0 0.0032 17.3 0.0 3.1 3 0 0 3 3 3 1 Helix-hairpin-helix motif Tex_N PF09371.5 KNE02471.1 - 0.0039 16.5 0.2 0.0099 15.2 0.1 1.6 1 0 0 1 1 1 1 Tex-like protein N-terminal domain XPG_I_2 PF12813.2 KNE02471.1 - 0.016 14.7 0.0 0.041 13.3 0.0 1.7 1 0 0 1 1 1 0 XPG domain containing HHH_5 PF14520.1 KNE02471.1 - 0.083 13.0 0.1 1 9.5 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain YycI PF09648.5 KNE02471.1 - 6 6.2 8.0 0.5 9.7 0.6 2.4 2 0 0 2 2 2 0 YycH protein Pkinase PF00069.20 KNE02473.1 - 2.8e-64 216.7 0.0 3.5e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE02473.1 - 9.1e-40 136.3 0.0 1.3e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNE02473.1 - 9.4e-06 24.7 0.0 2.9e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KNE02473.1 - 0.079 12.0 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RPAP1_C PF08620.5 KNE02474.1 - 2.1e-34 117.1 0.1 5.3e-34 115.9 0.0 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 KNE02474.1 - 1.9e-15 56.1 3.3 4.2e-15 55.0 2.3 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal NOC3p PF07540.6 KNE02474.1 - 0.059 13.6 0.0 0.23 11.7 0.0 2.0 1 1 0 1 1 1 0 Nucleolar complex-associated protein HEAT PF02985.17 KNE02474.1 - 0.12 12.5 0.2 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat DUF2890 PF11081.3 KNE02475.1 - 4.3 7.3 5.9 1.6 8.7 2.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2890) DUF1620 PF07774.8 KNE02476.1 - 5e-55 186.1 0.3 1.3e-54 184.7 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) Zn_clus PF00172.13 KNE02477.1 - 3.1e-05 23.8 12.1 6.4e-05 22.7 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2770 PF10968.3 KNE02477.1 - 0.045 13.4 0.3 0.14 11.8 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2770) Rpr2 PF04032.11 KNE02480.1 - 1.2e-08 34.6 0.7 2e-08 33.9 0.5 1.3 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain RNF111_N PF15303.1 KNE02480.1 - 0.074 12.5 3.6 0.16 11.4 2.5 1.5 1 1 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus Pex24p PF06398.6 KNE02481.1 - 7.7e-54 182.8 1.1 9.5e-54 182.5 0.8 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin SIR2 PF02146.12 KNE02482.1 - 3.2e-36 124.7 0.0 1.5e-19 70.3 0.0 2.4 2 0 0 2 2 2 2 Sir2 family BLOC1_2 PF10046.4 KNE02482.1 - 0.021 14.9 1.1 0.04 14.0 0.1 2.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Pkinase PF00069.20 KNE02483.1 - 1.5e-75 253.6 0.0 2.5e-75 253.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE02483.1 - 3e-38 131.3 0.0 6e-38 130.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 KNE02483.1 - 2.2e-18 66.1 0.8 2.2e-18 66.1 0.6 1.9 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 KNE02483.1 - 1.7e-08 33.7 0.0 8.3e-08 31.5 0.0 2.1 3 0 0 3 3 3 1 Kinase-like YukC PF10140.4 KNE02483.1 - 0.00015 20.5 0.1 0.00025 19.7 0.1 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC DUF2443 PF10398.4 KNE02483.1 - 0.015 15.0 0.1 0.042 13.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Kdo PF06293.9 KNE02483.1 - 0.021 13.8 0.1 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Innate_immun PF12782.2 KNE02483.1 - 0.046 12.9 2.2 0.074 12.2 1.5 1.3 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family APH PF01636.18 KNE02483.1 - 0.075 12.7 0.9 0.37 10.4 0.6 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Zip PF02535.17 KNE02483.1 - 3.9 6.3 6.5 6.2 5.7 4.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PWI PF01480.12 KNE02484.1 - 4.3e-17 61.9 0.0 9.2e-17 60.9 0.0 1.6 1 0 0 1 1 1 1 PWI domain YTH PF04146.10 KNE02485.1 - 1.2e-45 154.5 1.2 1.8e-45 153.9 0.7 1.4 2 0 0 2 2 2 1 YT521-B-like domain COQ7 PF03232.8 KNE02486.1 - 3.4e-76 254.5 0.1 4.3e-76 254.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 KNE02486.1 - 0.057 13.7 0.0 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 Rubrerythrin Nuf2 PF03800.9 KNE02487.1 - 7.6e-42 142.7 1.9 7.6e-42 142.7 1.3 2.4 2 1 0 2 2 2 1 Nuf2 family Baculo_PEP_C PF04513.7 KNE02487.1 - 0.026 14.3 26.5 0.25 11.1 3.0 4.2 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus TAF8_C PF10406.4 KNE02487.1 - 0.035 14.1 6.9 0.21 11.6 0.2 3.4 2 1 1 3 3 3 0 Transcription factor TFIID complex subunit 8 C-term DUF357 PF04010.8 KNE02487.1 - 0.18 11.5 4.9 9.1 6.0 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF357) CENP-F_leu_zip PF10473.4 KNE02487.1 - 1.2 8.9 46.2 0.15 11.8 6.2 3.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 KNE02487.1 - 2.3 7.1 42.7 1.3 8.0 7.3 3.1 2 1 1 3 3 3 0 Autophagy protein Apg6 MFS_1 PF07690.11 KNE02488.1 - 1.4e-42 145.6 55.8 1.5e-41 142.2 38.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KNE02488.1 - 4.7e-18 64.7 14.3 4.7e-18 64.7 9.9 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KNE02488.1 - 9.4e-12 44.2 16.4 9.4e-12 44.2 11.4 2.8 2 1 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.8 KNE02488.1 - 0.0003 19.0 4.2 0.00062 18.0 2.9 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector DUF983 PF06170.7 KNE02488.1 - 2.3 8.4 14.0 7.1 6.8 1.1 4.1 2 1 1 3 3 3 0 Protein of unknown function (DUF983) Git3 PF11710.3 KNE02489.1 - 5.3e-79 264.4 18.8 1e-78 263.5 13.1 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 KNE02489.1 - 1.6e-33 114.3 2.0 1.6e-33 114.3 1.4 2.1 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF3139 PF11337.3 KNE02489.1 - 0.044 14.0 0.5 0.16 12.2 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) DUF4064 PF13273.1 KNE02489.1 - 0.8 9.8 4.3 2.3 8.3 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Dicty_CAR PF05462.6 KNE02489.1 - 1.8 7.3 20.9 0.2 10.5 8.7 2.1 2 0 0 2 2 2 0 Slime mold cyclic AMP receptor AA_permease PF00324.16 KNE02491.1 - 3.9e-105 351.9 34.1 4.5e-105 351.7 23.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KNE02491.1 - 8.9e-25 87.0 37.9 1.3e-24 86.5 26.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 KNE02491.1 - 0.08 12.6 2.8 0.12 12.0 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) UPF0640 PF15114.1 KNE02491.1 - 0.2 11.1 4.3 0.87 9.1 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0640 AMPKBI PF04739.10 KNE02493.1 - 4.2e-30 103.5 1.9 4.2e-30 103.5 1.3 2.3 3 0 0 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interation domain STE2 PF02116.10 KNE02495.1 - 1.9e-74 250.3 25.2 2.2e-74 250.0 17.5 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF347 PF03988.7 KNE02495.1 - 0.34 10.8 5.5 2.3 8.1 0.0 3.3 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) Y_phosphatase2 PF03162.8 KNE02496.1 - 3.2e-58 195.7 0.1 4.7e-58 195.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 KNE02496.1 - 1.5e-06 28.5 0.0 3.6e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 KNE02496.1 - 0.0019 17.8 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KNE02496.1 - 0.002 17.5 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF2416 PF10315.4 KNE02497.1 - 9.2e-42 141.6 0.7 1.1e-41 141.4 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2416) Histone PF00125.19 KNE02498.1 - 1.7e-31 108.1 0.4 4.1e-31 106.9 0.3 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KNE02498.1 - 3.7e-06 27.0 0.0 7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S DUF2102 PF09875.4 KNE02498.1 - 0.0026 17.2 0.0 0.0059 16.1 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2102) CBFD_NFYB_HMF PF00808.18 KNE02498.1 - 0.0075 16.3 0.1 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KNE02498.1 - 0.11 12.2 0.1 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 KNE02499.1 - 2.6e-15 56.2 0.2 3.2e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KNE02499.1 - 2.5e-05 24.3 0.1 3.3e-05 23.9 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KNE02499.1 - 2.6e-05 24.0 0.1 3.6e-05 23.6 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KNE02499.1 - 3.5e-05 23.7 0.1 5.9e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KNE02499.1 - 0.00041 19.7 0.0 0.00044 19.6 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 KNE02499.1 - 0.0026 17.4 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 KNE02499.1 - 0.057 13.7 0.1 0.11 12.8 0.1 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 KNE02499.1 - 0.12 12.1 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Glyco_transf_15 PF01793.11 KNE02500.1 - 2.6e-123 411.1 12.3 2.6e-123 411.1 8.5 1.6 2 0 0 2 2 2 1 Glycolipid 2-alpha-mannosyltransferase Sds3 PF08598.6 KNE02502.1 - 1.1e-48 165.4 10.5 3.3e-48 163.9 7.3 1.7 1 1 0 1 1 1 1 Sds3-like DUF3523 PF12037.3 KNE02502.1 - 0.00039 19.4 4.1 0.00069 18.6 2.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) STAT_int PF02865.12 KNE02502.1 - 0.036 14.0 1.6 1.3 9.0 0.3 2.4 2 0 0 2 2 2 0 STAT protein, protein interaction domain DUF1825 PF08855.5 KNE02502.1 - 0.94 9.5 6.5 16 5.5 3.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1825) Acetyltransf_1 PF00583.19 KNE02503.1 - 1.9e-05 24.5 0.0 4.5e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KNE02503.1 - 0.00012 22.2 0.1 0.00016 21.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KNE02503.1 - 0.00024 21.0 0.1 0.00041 20.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KNE02503.1 - 0.0017 18.5 0.1 0.011 15.8 0.1 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-H2C2 PF09337.5 KNE02504.1 - 2.8e-19 68.2 4.5 6.3e-19 67.0 3.1 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 KNE02504.1 - 2.9e-06 27.1 0.0 6.7e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KNE02504.1 - 0.00016 21.6 0.0 0.00035 20.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KNE02504.1 - 0.016 15.3 0.0 0.046 13.8 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KNE02504.1 - 0.056 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KNE02504.1 - 0.072 13.2 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CPSase_L_D2 PF02786.12 KNE02505.1 - 1.4e-115 383.9 0.6 6e-84 280.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 KNE02505.1 - 1.2e-45 154.1 0.0 2.9e-45 152.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.16 KNE02505.1 - 5.6e-44 149.2 0.0 1.5e-43 147.8 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.23 KNE02505.1 - 1.2e-43 148.7 0.0 2.6e-43 147.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_chain PF00289.17 KNE02505.1 - 1.8e-41 140.7 0.0 8.7e-21 74.0 0.0 2.9 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 KNE02505.1 - 2.9e-40 136.8 0.0 5.7e-40 135.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 KNE02505.1 - 1.2e-34 119.7 0.3 9e-23 80.9 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 KNE02505.1 - 1.4e-32 112.7 0.2 7e-32 110.4 0.0 2.5 3 0 0 3 3 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 KNE02505.1 - 2.7e-21 75.6 0.0 8.8e-11 41.1 0.0 3.5 3 0 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 KNE02505.1 - 2.4e-20 72.2 0.0 9.4e-20 70.3 0.0 2.1 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.8 KNE02505.1 - 2.7e-15 56.2 1.1 1.3e-08 34.4 0.2 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KNE02505.1 - 4.4e-15 55.4 0.2 7.5e-08 31.9 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.9 KNE02505.1 - 1.7e-07 31.2 0.6 0.0058 16.5 0.1 2.9 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 KNE02505.1 - 2.5e-06 27.0 0.1 0.00046 19.7 0.1 3.3 3 0 0 3 3 3 1 RimK-like ATP-grasp domain Peptidase_C26 PF07722.8 KNE02505.1 - 5.4e-05 22.7 0.2 0.0017 17.8 0.1 2.6 1 1 0 1 1 1 1 Peptidase C26 SUKH_6 PF14568.1 KNE02505.1 - 0.07 13.6 0.1 0.72 10.3 0.0 2.4 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall MFS_1 PF07690.11 KNE02508.1 - 1.3e-44 152.3 23.3 1.3e-44 152.3 16.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KNE02508.1 - 1.7e-10 40.0 10.1 1.7e-10 40.0 7.0 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter BT1 PF03092.11 KNE02508.1 - 0.00051 18.8 0.6 0.00086 18.1 0.4 1.3 1 0 0 1 1 1 1 BT1 family ESSS PF10183.4 KNE02508.1 - 0.023 15.0 0.0 0.064 13.6 0.0 1.7 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fusion_gly PF00523.13 KNE02508.1 - 8.2 4.3 7.5 14 3.6 5.2 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 TrkH PF02386.11 KNE02509.1 - 3.2e-130 433.8 15.3 5.5e-128 426.4 7.0 2.1 2 0 0 2 2 2 2 Cation transport protein Brix PF04427.13 KNE02510.1 - 8.3e-45 152.8 1.2 1.1e-44 152.4 0.8 1.1 1 0 0 1 1 1 1 Brix domain SRP-alpha_N PF04086.8 KNE02512.1 - 3.1 7.0 8.4 3.4 6.9 5.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RICTOR_N PF14664.1 KNE02513.1 - 1.8e-71 240.7 2.6 7.2e-71 238.7 1.8 1.9 1 1 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 KNE02513.1 - 2.6e-62 209.7 6.9 5.2e-62 208.8 0.9 3.9 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.1 KNE02513.1 - 4.1e-15 55.4 0.4 4e-12 45.8 0.0 4.2 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.1 KNE02513.1 - 9.4e-07 28.7 0.0 6.8e-06 25.9 0.0 2.7 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF3388 PF11868.3 KNE02514.1 - 0.042 12.9 0.4 0.09 11.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3388) Barstar PF01337.13 KNE02514.1 - 0.11 12.4 0.2 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 Barstar (barnase inhibitor) YjgP_YjgQ PF03739.9 KNE02514.1 - 0.78 8.4 2.0 0.94 8.1 1.4 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family ASF1_hist_chap PF04729.8 KNE02515.1 - 2.2e-66 222.2 0.0 3.2e-66 221.7 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone TFIIF_alpha PF05793.7 KNE02515.1 - 0.0022 16.4 20.8 0.0025 16.2 14.4 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TLP-20 PF06088.6 KNE02515.1 - 0.38 10.4 8.1 0.6 9.7 5.6 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SURF2 PF05477.6 KNE02515.1 - 0.71 8.9 14.4 1.1 8.3 10.0 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Nop14 PF04147.7 KNE02515.1 - 0.91 7.3 27.5 0.99 7.2 19.0 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KNE02515.1 - 1.1 7.6 25.9 1.2 7.5 18.0 1.0 1 0 0 1 1 1 0 Daxx Family Merozoite_SPAM PF07133.6 KNE02515.1 - 2.5 7.9 30.3 3.2 7.5 21.0 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Usp PF00582.21 KNE02515.1 - 3.5 7.8 6.7 5.9 7.0 4.7 1.4 1 0 0 1 1 1 0 Universal stress protein family DUF2890 PF11081.3 KNE02515.1 - 6.3 6.8 21.5 9.7 6.1 14.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CENP-T PF15511.1 KNE02515.1 - 7.2 5.7 20.8 8.6 5.4 14.4 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TAFA PF12020.3 KNE02519.1 - 0.11 12.5 1.3 0.19 11.8 0.9 1.5 1 0 0 1 1 1 0 TAFA family Mem_trans PF03547.13 KNE02520.1 - 8.5e-29 100.0 0.3 1.2e-28 99.4 0.2 1.2 1 0 0 1 1 1 1 Membrane transport protein K-cyclin_vir_C PF09080.5 KNE02520.1 - 0.095 12.9 0.3 0.16 12.1 0.2 1.3 1 0 0 1 1 1 0 K cyclin, C terminal DUF4333 PF14230.1 KNE02521.1 - 0.11 12.5 0.1 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4333) Ras PF00071.17 KNE02522.1 - 3.3e-48 163.1 0.7 3.8e-48 162.9 0.5 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNE02522.1 - 1.2e-16 61.2 0.1 1.9e-16 60.6 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KNE02522.1 - 2.3e-07 30.4 0.2 4.3e-07 29.5 0.1 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 KNE02522.1 - 4.3e-05 22.8 0.1 5.1e-05 22.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KNE02522.1 - 0.0096 15.8 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KNE02522.1 - 0.011 14.9 0.0 0.017 14.3 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit GDA1_CD39 PF01150.12 KNE02524.1 - 6.4e-77 258.8 0.0 2.1e-76 257.1 0.0 1.8 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family UCH PF00443.24 KNE02525.1 - 2.5e-47 161.2 0.0 3.5e-46 157.4 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KNE02525.1 - 1.3e-11 44.5 0.0 1.2e-10 41.3 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Cas_Cmr5 PF09701.5 KNE02525.1 - 0.41 10.8 1.6 0.58 10.3 0.1 1.9 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cmr5) RRM_1 PF00076.17 KNE02527.1 - 3.2e-49 164.4 0.7 4.2e-17 61.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNE02527.1 - 1.6e-32 111.3 0.1 5.1e-11 42.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNE02527.1 - 1.6e-25 88.7 0.1 1.5e-07 31.1 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KNE02527.1 - 0.12 12.1 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Met_10 PF02475.11 KNE02528.1 - 8.2e-11 41.8 0.0 7.4e-10 38.7 0.0 2.1 2 0 0 2 2 2 1 Met-10+ like-protein MTS PF05175.9 KNE02528.1 - 0.0039 16.5 0.0 0.013 14.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KNE02528.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain zf-H2C2_2 PF13465.1 KNE02529.1 - 4.4e-14 51.9 13.1 6.3e-08 32.5 0.4 4.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 KNE02529.1 - 5.1e-14 51.6 15.7 1.2e-06 28.5 2.5 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNE02529.1 - 2.4e-12 46.2 13.9 0.00045 20.3 2.1 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 KNE02529.1 - 2.6e-06 27.4 7.7 0.00032 20.7 0.3 4.3 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KNE02529.1 - 3.1e-05 23.9 12.5 0.0019 18.2 0.6 4.0 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Amidase PF01425.16 KNE02529.1 - 0.045 12.6 0.2 0.069 11.9 0.1 1.2 1 0 0 1 1 1 0 Amidase zf-C2HC_2 PF13913.1 KNE02529.1 - 0.16 11.7 0.1 0.16 11.7 0.0 2.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type FYVE PF01363.16 KNE02529.1 - 0.53 10.2 6.3 1.2 9.0 4.4 1.7 1 1 0 1 1 1 0 FYVE zinc finger Zn_ribbon_recom PF13408.1 KNE02529.1 - 0.58 10.4 4.7 0.19 11.9 0.5 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain C1_4 PF07975.7 KNE02529.1 - 2.4 8.2 5.4 9.3 6.3 2.3 2.6 2 1 1 3 3 2 0 TFIIH C1-like domain zf-BED PF02892.10 KNE02529.1 - 9 6.1 12.5 2.7 7.8 1.2 3.3 2 1 1 3 3 3 0 BED zinc finger Bac_surface_Ag PF01103.18 KNE02531.1 - 2.2e-41 142.4 6.4 2.8e-41 142.0 4.4 1.1 1 0 0 1 1 1 1 Surface antigen DFP PF04127.10 KNE02532.1 - 2.7e-19 69.5 0.0 1.3e-11 44.4 0.0 2.6 2 1 1 3 3 3 2 DNA / pantothenate metabolism flavoprotein Pro_isomerase PF00160.16 KNE02533.1 - 4.9e-27 95.0 0.2 5.4e-27 94.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cyclin_N PF00134.18 KNE02534.1 - 9.7e-13 47.7 0.8 2.3e-12 46.5 0.6 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain TRAM_LAG1_CLN8 PF03798.11 KNE02535.1 - 1.8e-39 135.3 26.8 1.8e-39 135.3 18.6 2.2 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KNE02535.1 - 4.4e-17 61.3 2.0 4.4e-17 61.3 1.4 2.0 2 0 0 2 2 2 1 TRAM1-like protein Aa_trans PF01490.13 KNE02536.1 - 2.1e-90 303.1 32.4 2.6e-90 302.8 22.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CENP-X PF09415.5 KNE02537.1 - 5.1e-17 61.4 0.4 1.9e-13 49.9 0.1 2.2 2 0 0 2 2 2 2 CENP-S associating Centromere protein X Ecm29 PF13001.2 KNE02537.1 - 0.021 13.3 0.0 0.026 13.0 0.0 1.1 1 0 0 1 1 1 0 Proteasome stabiliser Dynactin_p62 PF05502.8 KNE02538.1 - 9.5e-12 44.4 9.9 1.3e-09 37.4 1.0 2.5 1 1 1 2 2 2 2 Dynactin p62 family Elf1 PF05129.8 KNE02538.1 - 0.26 11.0 2.5 3.1 7.5 0.8 2.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-C3HC PF07967.8 KNE02538.1 - 0.6 9.8 0.0 0.6 9.8 0.0 2.4 1 1 1 2 2 2 0 C3HC zinc finger-like DUF4319 PF14203.1 KNE02538.1 - 0.79 9.3 2.5 2.5 7.7 1.1 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4319) zf-RING_6 PF14835.1 KNE02538.1 - 2 8.2 7.6 1.5 8.6 0.0 2.8 3 0 0 3 3 3 0 zf-RING of BARD1-type protein Gly-zipper_Omp PF13488.1 KNE02539.1 - 0.0034 16.9 19.3 0.0034 16.9 13.4 3.7 3 0 0 3 3 3 1 Glycine zipper DUF421 PF04239.7 KNE02539.1 - 0.062 12.8 0.1 0.062 12.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF421) Patched PF02460.13 KNE02540.1 - 1.9e-66 224.6 26.9 2.2e-63 214.4 16.8 4.5 3 1 0 3 3 3 2 Patched family Sterol-sensing PF12349.3 KNE02540.1 - 3.7e-47 159.6 7.7 3.7e-47 159.6 5.3 3.1 3 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 KNE02540.1 - 0.00044 17.8 11.0 0.0008 16.9 7.6 1.3 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family dCMP_cyt_deam_1 PF00383.17 KNE02541.1 - 3.3e-26 90.8 1.8 5.1e-26 90.2 1.3 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_18 PF13238.1 KNE02541.1 - 0.01 16.1 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 KNE02541.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Dynamin family FAA_hydrolase PF01557.13 KNE02542.1 - 1.3e-49 168.5 0.0 1.7e-49 168.2 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SH2_2 PF14633.1 KNE02542.1 - 0.038 13.0 0.0 0.052 12.5 0.0 1.3 1 0 0 1 1 1 0 SH2 domain FTR1 PF03239.9 KNE02544.1 - 5e-97 324.5 8.3 6.3e-97 324.2 5.7 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3112 PF11309.3 KNE02544.1 - 0.0018 18.0 1.7 0.0018 18.0 1.2 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3112) DUF4293 PF14126.1 KNE02544.1 - 0.83 9.5 7.8 0.78 9.6 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) Glyco_hydro_81 PF03639.8 KNE02546.1 - 1.1e-214 714.5 19.7 1.3e-214 714.2 13.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 DUF2353 PF09789.4 KNE02550.1 - 0.053 12.7 0.2 0.061 12.5 0.1 1.3 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) NST1 PF13945.1 KNE02550.1 - 0.41 10.7 4.8 0.4 10.7 3.3 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator BRF1 PF07741.8 KNE02550.1 - 0.41 10.8 3.5 0.45 10.7 2.5 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain BLVR PF06375.6 KNE02550.1 - 2.2 8.1 5.7 1.9 8.2 4.0 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) MFS_1 PF07690.11 KNE02552.1 - 1.1e-11 44.0 43.4 1.5e-07 30.5 15.7 3.9 2 2 1 3 3 3 3 Major Facilitator Superfamily Rod-binding PF10135.4 KNE02552.1 - 0.088 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Rod binding protein Bromodomain PF00439.20 KNE02553.1 - 2.9e-15 55.9 1.1 7e-15 54.7 0.2 2.2 2 0 0 2 2 2 1 Bromodomain zf-Tim10_DDP PF02953.10 KNE02554.1 - 9.1e-22 76.1 5.3 1.2e-21 75.7 3.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Phasin_2 PF09361.5 KNE02554.1 - 0.056 13.4 0.1 0.27 11.2 0.0 1.9 1 1 1 2 2 2 0 Phasin protein Mmp37 PF09139.6 KNE02554.1 - 0.076 12.0 0.3 0.08 11.9 0.2 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 E_Pc_C PF06752.7 KNE02554.1 - 0.078 12.4 0.3 0.072 12.5 0.2 1.1 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Gemini_AL1_M PF08283.6 KNE02554.1 - 0.09 12.6 0.2 0.097 12.5 0.1 1.2 1 0 0 1 1 1 0 Geminivirus rep protein central domain tRNA-synt_2 PF00152.15 KNE02555.1 - 1.4e-73 247.6 0.0 1.6e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KNE02555.1 - 2.4e-06 27.3 0.0 6.4e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_His PF13393.1 KNE02555.1 - 0.079 12.0 0.0 0.18 10.7 0.0 1.5 1 1 0 1 1 1 0 Histidyl-tRNA synthetase PHP PF02811.14 KNE02557.1 - 5.2e-08 32.8 0.9 8.8e-08 32.1 0.7 1.5 1 1 0 1 1 1 1 PHP domain tRNA-synt_2b PF00587.20 KNE02558.1 - 4.5e-23 81.6 0.2 8.6e-23 80.7 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.6 KNE02558.1 - 1.5e-22 79.2 0.1 3.3e-22 78.1 0.1 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 KNE02558.1 - 1.2e-18 66.7 0.0 4.1e-18 65.1 0.0 2.0 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.10 KNE02558.1 - 3.1e-06 27.0 1.1 5.4e-06 26.2 0.8 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_2 PF00152.15 KNE02559.1 - 5.5e-76 255.5 0.0 1e-75 254.5 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KNE02559.1 - 3.5e-12 45.9 0.1 8.7e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ins134_P3_kin PF05770.6 KNE02559.1 - 0.045 12.7 0.0 0.084 11.8 0.0 1.4 1 0 0 1 1 1 0 Inositol 1, 3, 4-trisphosphate 5/6-kinase Lyase_1 PF00206.15 KNE02560.1 - 7.5e-101 337.4 0.0 1.2e-100 336.7 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 KNE02560.1 - 2.7e-26 91.4 0.1 7.7e-26 89.9 0.0 1.8 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal NUC153 PF08159.7 KNE02564.1 - 1.2e-14 53.6 1.1 3.4e-14 52.1 0.8 1.9 1 0 0 1 1 1 1 NUC153 domain Isy1 PF06246.7 KNE02565.1 - 1.2e-47 162.4 5.2 2e-46 158.5 1.3 2.0 1 1 0 2 2 2 2 Isy1-like splicing family DUF904 PF06005.7 KNE02565.1 - 0.17 12.2 1.3 0.32 11.2 0.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Isochorismatase PF00857.15 KNE02566.1 - 9.4e-23 81.0 3.4 2.3e-22 79.7 2.3 1.6 1 1 0 1 1 1 1 Isochorismatase family Gly_transf_sug PF04488.10 KNE02567.1 - 1.1e-14 54.6 0.8 9.8e-14 51.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KNE02567.1 - 0.0074 15.4 1.2 0.014 14.5 0.9 1.5 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein DEAD PF00270.24 KNE02568.1 - 1.4e-45 154.7 0.0 6.7e-45 152.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNE02568.1 - 3e-28 97.4 0.0 8.6e-28 96.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNE02568.1 - 0.00095 19.0 0.0 0.002 17.9 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Bap31 PF05529.7 KNE02569.1 - 0.023 14.1 0.3 0.026 13.9 0.2 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like NAD_kinase PF01513.16 KNE02570.1 - 1.1e-71 240.9 0.0 1.6e-71 240.3 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 KNE02570.1 - 0.0082 15.5 0.0 0.025 14.0 0.0 1.8 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain GDA1_CD39 PF01150.12 KNE02571.1 - 1.1e-109 366.8 0.0 1.4e-109 366.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family CRF1 PF10380.4 KNE02572.1 - 4.8e-28 97.9 7.2 4.8e-28 97.9 5.0 5.6 5 2 0 5 5 5 2 Transcription factor CRF1 PHD PF00628.24 KNE02573.1 - 1.3e-08 34.3 7.7 3.6e-08 32.9 5.3 1.8 1 1 0 1 1 1 1 PHD-finger SPOC PF07744.8 KNE02573.1 - 4.3e-08 33.6 0.0 1.4e-07 31.9 0.0 2.0 2 0 0 2 2 2 1 SPOC domain PHD_2 PF13831.1 KNE02573.1 - 0.00042 19.5 1.3 0.00042 19.5 0.9 2.1 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.17 KNE02573.1 - 0.23 11.1 2.9 0.13 12.0 0.2 1.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rad9_Rad53_bind PF08605.5 KNE02574.1 - 1.6e-24 86.1 0.2 3.2e-24 85.1 0.1 1.6 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 KNE02574.1 - 5.6e-10 39.2 0.4 1.2e-08 34.9 0.0 2.7 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Pro_dh PF01619.13 KNE02575.1 - 5.2e-49 166.9 0.2 6.4e-49 166.6 0.1 1.2 1 0 0 1 1 1 1 Proline dehydrogenase SLS PF14611.1 KNE02578.1 - 1.2e-26 93.5 3.2 2.8e-26 92.2 2.2 1.7 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Secretin_N PF03958.12 KNE02578.1 - 0.061 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain BLOC1_2 PF10046.4 KNE02579.1 - 0.023 14.8 0.2 0.034 14.2 0.1 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ABC1 PF03109.11 KNE02580.1 - 1.2e-27 96.2 0.5 3e-27 94.9 0.3 1.7 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 KNE02580.1 - 0.012 15.3 0.0 0.13 11.9 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Rep_Org_C PF06926.6 KNE02580.1 - 0.095 12.8 1.2 0.71 10.0 0.1 2.7 2 1 1 3 3 3 0 Putative replisome organiser protein C-terminus WD40 PF00400.27 KNE02581.1 - 3.5e-64 210.5 11.1 1.8e-08 33.9 0.0 11.4 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 KNE02581.1 - 1.2e-41 141.6 5.9 2e-41 140.9 4.1 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain PQQ_2 PF13360.1 KNE02581.1 - 0.0024 17.3 3.0 0.019 14.3 0.6 3.0 2 1 0 2 2 2 1 PQQ-like domain Gmad1 PF10647.4 KNE02581.1 - 0.0086 15.4 0.3 0.029 13.7 0.2 1.9 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 KNE02581.1 - 0.013 13.7 4.2 1.4 6.9 0.1 4.4 4 2 2 6 6 6 0 Nucleoporin Nup120/160 MSC PF09402.5 KNE02589.1 - 1.1e-55 188.6 0.3 1.4e-55 188.3 0.2 1.0 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain MSC PF09402.5 KNE02590.1 - 2.2e-30 105.5 3.0 2.3e-30 105.4 2.1 1.0 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain Peptidase_S49_N PF08496.5 KNE02590.1 - 0.042 13.6 1.8 0.18 11.5 1.3 1.8 1 1 0 1 1 1 0 Peptidase family S49 N-terminal DUF2500 PF10694.4 KNE02590.1 - 0.076 13.0 0.7 0.11 12.4 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2500) ATP-synt_A PF00119.15 KNE02590.1 - 0.082 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 ATP synthase A chain Neur_chan_memb PF02932.11 KNE02590.1 - 0.11 12.4 1.0 0.12 12.2 0.7 1.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RWD PF05773.17 KNE02591.1 - 6.2e-21 74.3 2.4 6.2e-21 74.3 1.7 1.8 2 0 0 2 2 2 1 RWD domain SH3_1 PF00018.23 KNE02593.1 - 1.7e-09 36.9 0.1 3.9e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KNE02593.1 - 1.2e-08 34.3 0.2 2.5e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KNE02593.1 - 3.7e-06 26.3 0.1 6.4e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Tom37 PF10568.4 KNE02594.1 - 0.054 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Pro_isomerase PF00160.16 KNE02599.1 - 7.3e-46 156.1 0.2 8.1e-46 156.0 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.1 KNE02599.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Redoxin PF08534.5 KNE02600.1 - 3e-26 91.6 0.0 3.5e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KNE02600.1 - 7.1e-05 22.4 0.0 9.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Avl9 PF09794.4 KNE02601.1 - 5.2e-121 403.6 8.2 5.2e-121 403.6 5.7 1.5 2 0 0 2 2 2 1 Transport protein Avl9 DUF2347 PF09804.4 KNE02601.1 - 1.1e-08 34.7 2.2 1.9e-08 33.9 1.5 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DENN PF02141.16 KNE02601.1 - 3.9e-05 23.4 3.9 3.9e-05 23.4 2.7 1.6 2 0 0 2 2 2 1 DENN (AEX-3) domain LRR_1 PF00560.28 KNE02601.1 - 0.12 12.4 1.3 7.1 7.0 0.0 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat SPA PF08616.5 KNE02601.1 - 1.1 9.0 8.5 0.89 9.2 0.1 3.4 4 0 0 4 4 4 0 Stabilization of polarity axis WD40 PF00400.27 KNE02602.1 - 1.7e-06 27.6 1.0 0.0018 18.1 0.1 3.6 4 1 0 4 4 4 2 WD domain, G-beta repeat ABC_membrane PF00664.18 KNE02603.1 - 3.1e-81 272.7 39.9 1.8e-47 162.0 4.3 3.0 3 1 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 KNE02603.1 - 2e-51 173.9 0.2 4.5e-30 104.7 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KNE02603.1 - 9.4e-10 38.0 4.7 7.1e-05 22.1 0.7 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KNE02603.1 - 3.8e-06 26.8 0.2 0.12 12.3 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.1 KNE02603.1 - 1e-05 25.6 0.5 0.011 15.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 KNE02603.1 - 2.1e-05 24.6 0.6 1.6 8.6 0.1 4.4 2 2 1 3 3 3 2 AAA domain AAA_25 PF13481.1 KNE02603.1 - 0.00013 21.4 0.0 0.25 10.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KNE02603.1 - 0.00027 20.1 0.6 0.15 11.2 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KNE02603.1 - 0.0003 20.2 0.2 1.1 8.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 KNE02603.1 - 0.00051 20.5 1.5 1.6 9.2 0.1 3.4 3 0 0 3 3 3 2 Miro-like protein AAA_23 PF13476.1 KNE02603.1 - 0.00093 19.5 2.1 0.32 11.3 0.2 3.2 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KNE02603.1 - 0.0045 17.7 1.0 2.8 8.7 0.0 3.7 4 0 0 4 4 3 1 AAA domain FtsK_SpoIIIE PF01580.13 KNE02603.1 - 0.016 14.7 0.1 5.1 6.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.12 KNE02603.1 - 0.017 14.9 2.1 1.7 8.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_18 PF13238.1 KNE02603.1 - 0.035 14.3 0.1 13 6.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 KNE02603.1 - 0.053 13.3 1.8 0.88 9.3 0.1 2.5 2 0 0 2 2 2 0 Dynamin family MobB PF03205.9 KNE02603.1 - 0.097 12.3 0.2 17 5.1 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 KNE02603.1 - 0.12 11.4 0.0 8 5.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Sec1 PF00995.18 KNE02605.1 - 1.9e-90 304.1 0.6 2.4e-90 303.8 0.4 1.0 1 0 0 1 1 1 1 Sec1 family TPT PF03151.11 KNE02607.1 - 6.6e-34 116.7 14.0 6.6e-34 116.7 9.7 2.0 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KNE02607.1 - 1.2e-16 60.5 10.2 1.3e-16 60.3 7.1 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KNE02607.1 - 0.00029 20.8 29.2 0.0013 18.7 11.8 2.8 2 1 0 2 2 2 2 EamA-like transporter family Fzo_mitofusin PF04799.8 KNE02607.1 - 0.24 10.7 1.7 0.39 10.0 1.1 1.3 1 0 0 1 1 1 0 fzo-like conserved region DUF1129 PF06570.6 KNE02607.1 - 0.31 10.3 6.7 0.047 12.9 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) MtN3_slv PF03083.11 KNE02607.1 - 0.34 10.8 7.2 0.26 11.1 2.8 2.4 1 1 1 2 2 2 0 Sugar efflux transporter for intercellular exchange Herpes_LMP1 PF05297.6 KNE02607.1 - 2.4 7.0 13.7 0.063 12.2 4.7 1.9 1 1 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Asp PF00026.18 KNE02608.1 - 2e-15 56.8 0.0 5e-15 55.5 0.0 1.7 2 1 0 2 2 2 1 Eukaryotic aspartyl protease Phage_CI_repr PF07022.8 KNE02608.1 - 0.045 13.8 0.0 0.1 12.6 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain HATPase_c PF02518.21 KNE02610.1 - 8.2e-28 96.3 0.0 1.1e-21 76.6 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KNE02610.1 - 5.2e-27 94.0 0.0 1e-26 93.1 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KNE02610.1 - 5.3e-12 45.5 0.3 1.7e-11 43.9 0.2 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 KNE02610.1 - 0.00029 20.9 1.9 0.0022 18.1 0.0 2.8 2 1 0 2 2 2 1 HAMP domain Mid2 PF04478.7 KNE02610.1 - 0.022 14.1 0.1 0.071 12.5 0.1 1.9 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DPPIV_N PF00930.16 KNE02611.1 - 6e-91 304.6 6.4 8.7e-91 304.1 4.4 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KNE02611.1 - 8.1e-43 146.1 0.1 1.3e-42 145.4 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KNE02611.1 - 9.5e-07 28.6 0.0 1.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KNE02611.1 - 0.015 14.6 0.0 0.034 13.5 0.0 1.6 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 KNE02611.1 - 0.039 12.4 0.0 0.079 11.4 0.0 1.5 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) LIP PF03583.9 KNE02611.1 - 0.078 12.1 0.3 13 4.8 0.0 2.7 3 0 0 3 3 3 0 Secretory lipase TCTP PF00838.12 KNE02612.1 - 1.1e-69 233.7 3.0 1.2e-69 233.5 2.1 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein GerPC PF10737.4 KNE02612.1 - 0.014 15.1 0.1 0.019 14.7 0.1 1.1 1 0 0 1 1 1 0 Spore germination protein GerPC DUF3893 PF13032.1 KNE02612.1 - 0.014 15.4 0.0 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3893) TroA PF01297.12 KNE02612.1 - 0.019 14.2 0.1 0.022 14.0 0.1 1.3 1 1 0 1 1 1 0 Periplasmic solute binding protein family PTPA PF03095.10 KNE02612.1 - 0.028 13.6 0.0 0.029 13.5 0.0 1.1 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein gp32 PF08804.5 KNE02612.1 - 0.05 13.7 0.1 0.17 11.9 0.0 1.9 2 0 0 2 2 2 0 gp32 DNA binding protein like TRM13 PF05206.9 KNE02614.1 - 1.7e-70 237.2 1.9 2.5e-70 236.7 1.3 1.2 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.7 KNE02614.1 - 3e-10 39.5 0.9 6.4e-10 38.5 0.6 1.6 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.1 KNE02614.1 - 3.6e-05 23.4 1.5 6e-05 22.7 1.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain BUD22 PF09073.5 KNE02615.1 - 5.6e-86 289.2 57.1 5.6e-86 289.2 39.5 1.4 1 1 0 1 1 1 1 BUD22 PRKCSH-like PF12999.2 KNE02616.1 - 1.3e-62 210.4 7.4 1.3e-62 210.4 5.1 2.7 2 1 1 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 KNE02616.1 - 1.2e-44 151.4 0.1 2.9e-44 150.2 0.0 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Med28 PF11594.3 KNE02616.1 - 0.016 15.4 2.9 0.018 15.2 0.2 2.4 2 1 1 3 3 3 0 Mediator complex subunit 28 Fib_alpha PF08702.5 KNE02616.1 - 0.02 15.0 14.8 0.088 12.9 0.5 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 KNE02616.1 - 0.16 11.0 5.3 0.29 10.2 0.5 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 KNE02616.1 - 0.6 9.6 18.3 0.018 14.6 5.8 2.6 2 1 0 2 2 2 0 IncA protein CENP-Q PF13094.1 KNE02616.1 - 0.69 9.9 16.5 0.046 13.7 4.7 2.7 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit PP_kinase_N PF13089.1 KNE02616.1 - 0.82 9.7 5.7 2.6 8.1 0.9 2.7 2 1 0 2 2 2 0 Polyphosphate kinase N-terminal domain Tropomyosin_1 PF12718.2 KNE02616.1 - 0.98 9.2 14.4 2.5 7.9 5.5 2.4 2 0 0 2 2 2 0 Tropomyosin like adh_short PF00106.20 KNE02618.1 - 1.8e-18 67.0 0.2 2.4e-18 66.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNE02618.1 - 1.8e-09 37.7 0.2 2.6e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KNE02618.1 - 0.0089 16.0 0.1 0.015 15.2 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KNE02618.1 - 0.018 14.7 0.1 0.034 13.8 0.1 1.5 1 1 0 1 1 1 0 KR domain THF_DHG_CYH_C PF02882.14 KNE02618.1 - 0.04 12.9 0.0 0.083 11.9 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Robl_LC7 PF03259.12 KNE02618.1 - 0.13 11.8 0.2 0.64 9.6 0.0 2.2 2 0 0 2 2 2 0 Roadblock/LC7 domain YCII PF03795.9 KNE02619.1 - 3.9e-05 23.7 0.0 4.6e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain UCH PF00443.24 KNE02621.1 - 3.2e-49 167.4 0.8 3.2e-49 167.4 0.5 2.5 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KNE02621.1 - 1.3e-12 47.8 2.1 1.7e-12 47.3 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Borrelia_orfA PF02414.10 KNE02622.1 - 0.047 12.8 0.4 0.072 12.1 0.3 1.2 1 0 0 1 1 1 0 Borrelia ORF-A DUF445 PF04286.7 KNE02622.1 - 0.1 12.0 1.3 0.29 10.6 1.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF2508 PF10704.4 KNE02622.1 - 0.17 12.0 1.8 3 8.0 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2508) Rtt106 PF08512.7 KNE02623.1 - 2.5e-19 69.0 0.6 5.4e-19 67.9 0.4 1.6 1 0 0 1 1 1 1 Histone chaperone Rttp106-like CENP-T PF15511.1 KNE02623.1 - 2.7 7.1 14.9 4.2 6.4 10.3 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T EF-hand_6 PF13405.1 KNE02624.1 - 0.0043 16.8 3.0 0.067 13.1 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 KNE02624.1 - 0.012 14.8 1.4 0.086 12.1 0.0 2.2 2 0 0 2 2 2 0 EF hand DUF1049 PF06305.6 KNE02624.1 - 0.099 12.1 0.7 0.9 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) EF-hand_5 PF13202.1 KNE02624.1 - 0.65 9.4 2.9 0.86 9.0 0.1 2.1 2 0 0 2 2 2 0 EF hand Aminotran_1_2 PF00155.16 KNE02625.1 - 3.6e-26 91.9 0.0 4.7e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KNE02625.1 - 0.00014 20.5 0.0 0.0002 20.0 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Alginate_lyase PF05426.7 KNE02625.1 - 0.083 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Alginate lyase PX PF00787.19 KNE02626.1 - 2.2e-13 49.9 0.9 6.7e-13 48.4 0.0 2.2 2 1 2 4 4 4 1 PX domain SNARE PF05739.14 KNE02626.1 - 1.9e-11 43.4 4.4 1.9e-11 43.4 3.1 1.9 2 0 0 2 2 2 1 SNARE domain Chordopox_A30L PF06015.7 KNE02626.1 - 0.022 14.3 0.5 0.049 13.2 0.4 1.6 1 0 0 1 1 1 0 Chordopoxvirus A30L protein TMP_2 PF06791.8 KNE02626.1 - 0.047 13.2 1.7 0.73 9.4 0.4 2.2 2 0 0 2 2 2 0 Prophage tail length tape measure protein Snapin_Pallidin PF14712.1 KNE02626.1 - 0.2 11.9 11.7 0.19 12.0 3.1 2.4 2 0 0 2 2 2 0 Snapin/Pallidin GCIP PF13324.1 KNE02626.1 - 0.91 8.6 7.4 1.2 8.2 5.1 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF948 PF06103.6 KNE02626.1 - 3.6 7.5 5.7 2.9 7.8 1.1 2.7 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.5 KNE02626.1 - 4.2 7.4 11.3 4.5 7.4 6.5 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 KNE02626.1 - 7.7 6.3 9.1 7.5 6.3 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2417 PF10329.4 KNE02627.1 - 9.3e-74 247.7 3.4 1.3e-73 247.2 2.3 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 KNE02627.1 - 5.1e-08 33.0 0.0 7.9e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KNE02627.1 - 0.0011 19.1 0.0 0.0019 18.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 KNE02627.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold HemY_N PF07219.8 KNE02629.1 - 0.23 11.0 2.5 0.33 10.5 1.7 1.2 1 0 0 1 1 1 0 HemY protein N-terminus FHA PF00498.21 KNE02630.1 - 4.6e-15 55.4 0.0 9.2e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 KNE02630.1 - 9.3e-07 28.5 9.8 9.3e-07 28.5 6.8 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KNE02630.1 - 0.0011 18.5 10.9 0.0024 17.4 7.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KNE02630.1 - 0.0087 16.1 7.1 0.023 14.8 4.9 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KNE02630.1 - 0.015 15.0 8.7 0.017 14.8 5.2 1.8 1 1 0 1 1 1 0 zinc-RING finger domain PHD PF00628.24 KNE02630.1 - 0.036 13.7 6.3 0.089 12.5 4.3 1.7 1 0 0 1 1 1 0 PHD-finger zf-Apc11 PF12861.2 KNE02630.1 - 0.054 13.3 4.8 0.12 12.1 3.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.6 KNE02630.1 - 0.24 11.4 3.9 0.65 10.0 2.7 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_2 PF13923.1 KNE02630.1 - 0.31 11.0 12.3 0.72 9.9 8.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sugar_tr PF00083.19 KNE02631.1 - 9.3e-89 298.0 28.8 1.1e-88 297.7 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNE02631.1 - 9.6e-20 70.5 32.0 1.1e-19 70.4 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KNE02631.1 - 7.9e-11 40.9 33.6 3.4e-06 25.7 2.9 3.5 2 2 1 3 3 3 3 MFS/sugar transport protein EcoR124_C PF12008.3 KNE02631.1 - 0.012 14.8 2.9 0.83 8.7 0.2 2.2 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal zf-met2 PF12907.2 KNE02631.1 - 0.12 12.3 0.1 0.34 10.9 0.1 1.8 1 0 0 1 1 1 0 Zinc-binding DUF3767 PF12597.3 KNE02631.1 - 0.17 11.5 0.8 0.86 9.2 0.5 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) Fungal_trans PF04082.13 KNE02632.1 - 2.5e-11 42.9 1.8 3.6e-11 42.4 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 KNE02635.1 - 9e-50 169.3 1.1 1.1e-49 169.0 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNE02635.1 - 1.9e-07 30.8 11.6 5.2e-07 29.4 8.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_1 PF00583.19 KNE02636.1 - 9.5e-16 57.6 0.0 1.5e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KNE02636.1 - 2e-08 34.2 0.0 2.5e-08 34.0 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KNE02636.1 - 1.7e-07 31.3 0.0 2.2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KNE02636.1 - 7.1e-07 29.4 0.0 8.3e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KNE02636.1 - 1.1e-05 25.4 0.1 3.3e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KNE02636.1 - 0.0015 18.3 0.1 0.0031 17.3 0.1 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase SCP2_2 PF13530.1 KNE02636.1 - 0.0016 17.8 0.9 0.019 14.3 0.1 2.5 1 1 2 3 3 3 1 Sterol carrier protein domain Acetyltransf_8 PF13523.1 KNE02636.1 - 0.0024 17.7 0.0 0.003 17.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4307 PF14155.1 KNE02636.1 - 0.069 12.9 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Mec-17 PF05301.6 KNE02636.1 - 0.074 12.9 0.0 0.25 11.2 0.0 1.9 1 1 1 2 2 2 0 Touch receptor neuron protein Mec-17 His_Phos_1 PF00300.17 KNE02637.1 - 2.5e-27 95.8 0.0 3.2e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Dirigent PF03018.9 KNE02637.1 - 0.11 11.9 0.0 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 Dirigent-like protein E1-E2_ATPase PF00122.15 KNE02638.1 - 9.1e-72 240.8 3.1 1.9e-71 239.7 2.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KNE02638.1 - 8.7e-32 110.1 2.9 8.7e-32 110.1 2.0 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KNE02638.1 - 1.1e-28 101.1 0.0 3.1e-27 96.3 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KNE02638.1 - 1.6e-19 69.6 0.0 3.6e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KNE02638.1 - 3.5e-15 56.6 0.0 7.2e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KNE02638.1 - 1.1e-14 53.6 0.0 2.4e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KNE02638.1 - 1.7e-06 27.7 0.4 0.00071 19.2 0.4 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase NatB_MDM20 PF09797.4 KNE02641.1 - 3.2e-37 128.0 15.2 1.2e-35 122.9 6.4 3.4 2 1 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_16 PF13432.1 KNE02641.1 - 1.5e-07 31.9 0.1 2.3e-05 24.9 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KNE02641.1 - 9.9e-07 29.0 2.5 0.00054 20.2 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KNE02641.1 - 0.00025 21.2 1.0 1 9.9 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KNE02641.1 - 0.00053 19.6 1.1 2.6 8.1 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KNE02641.1 - 0.0055 17.2 0.0 3 8.7 0.0 4.4 3 1 2 5 5 5 1 Tetratricopeptide repeat Complex1_LYR PF05347.10 KNE02642.1 - 2.4e-06 27.2 0.6 3.7e-06 26.6 0.4 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KNE02642.1 - 0.0013 18.8 0.4 0.0021 18.2 0.3 1.3 1 0 0 1 1 1 1 Complex1_LYR-like LRR_6 PF13516.1 KNE02644.1 - 8e-07 28.4 1.5 4.6 7.6 0.0 6.4 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.2 KNE02644.1 - 2.9e-06 26.7 4.6 0.067 12.8 0.4 5.1 3 2 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KNE02644.1 - 0.0023 17.8 1.9 20 5.9 0.0 5.7 6 1 0 6 6 6 1 Leucine rich repeat LRR_1 PF00560.28 KNE02644.1 - 0.0046 16.7 5.7 9.9 6.6 0.3 4.8 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.1 KNE02644.1 - 0.037 13.7 3.2 1 9.1 0.0 4.0 3 2 1 4 4 4 0 Leucine rich repeat S1FA PF04689.8 KNE02644.1 - 0.085 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA HMG_box PF00505.14 KNE02645.1 - 4.2e-17 62.1 2.3 4.2e-17 62.1 1.6 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KNE02645.1 - 7e-07 29.5 0.7 7e-07 29.5 0.5 2.5 3 0 0 3 3 3 1 HMG-box domain YMF19 PF02326.10 KNE02649.1 - 0.91 10.1 4.3 1 9.9 3.0 1.2 1 1 0 1 1 1 0 Plant ATP synthase F0 CIAPIN1 PF05093.8 KNE02655.1 - 4.4e-36 122.9 2.5 1.1e-35 121.7 1.7 1.7 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Kinetochor_Ybp2 PF08568.5 KNE02655.1 - 0.016 13.4 0.1 0.043 12.0 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family, YAP/Alf4/glomulin DUF2874 PF11396.3 KNE02655.1 - 0.28 11.1 2.0 0.97 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2874) Ndc80_HEC PF03801.8 KNE02657.1 - 1.7e-40 138.0 1.7 2.2e-40 137.7 0.1 1.9 2 0 0 2 2 2 1 HEC/Ndc80p family TMF_TATA_bd PF12325.3 KNE02657.1 - 0.0029 17.3 6.3 0.0029 17.3 4.3 5.0 2 2 1 4 4 4 1 TATA element modulatory factor 1 TATA binding DUF1640 PF07798.6 KNE02657.1 - 0.016 15.2 10.1 0.016 15.2 7.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1640) MRP-L20 PF12824.2 KNE02658.1 - 4.3e-50 169.8 3.9 4.9e-50 169.7 2.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 KNE02658.1 - 2.3e-05 24.3 0.4 4.2e-05 23.4 0.3 1.5 1 1 0 1 1 1 1 Neugrin CAP59_mtransfer PF11735.3 KNE02658.1 - 0.11 11.6 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 DUF2508 PF10704.4 KNE02658.1 - 0.16 12.1 3.1 0.28 11.3 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Plasmodium_HRP PF05403.6 KNE02659.1 - 8.4e-06 25.5 11.9 8.7e-06 25.4 8.3 1.2 1 0 0 1 1 1 1 Plasmodium histidine-rich protein (HRPII/III) BUD22 PF09073.5 KNE02659.1 - 3.1 6.7 12.9 3.2 6.7 9.0 1.0 1 0 0 1 1 1 0 BUD22 Nop25 PF09805.4 KNE02659.1 - 4 7.4 10.9 6.8 6.7 7.6 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Cytochrome-c551 PF10643.4 KNE02659.1 - 5.3 6.2 9.3 6.2 6.0 6.5 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 FUSC PF04632.7 KNE02659.1 - 7.8 4.7 11.0 8.2 4.7 7.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family SAPS PF04499.10 KNE02659.1 - 8.4 4.9 7.7 9.1 4.7 5.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein eIF-3c_N PF05470.7 KNE02659.1 - 9.8 4.1 9.3 12 3.8 6.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus C2 PF00168.25 KNE02661.1 - 7.9e-08 32.0 0.0 1.5e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain PAP2 PF01569.16 KNE02663.1 - 4.5e-13 48.9 9.0 4.5e-13 48.9 6.2 2.5 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 KNE02663.1 - 5e-06 26.1 7.2 1.1e-05 25.0 5.0 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 KNE02663.1 - 7.1 6.9 13.8 0.37 11.1 5.2 2.2 2 0 0 2 2 2 0 PAP2 superfamily C-terminal RNA_pol_3_Rpc31 PF11705.3 KNE02667.1 - 2.5e-53 181.4 16.4 2.7e-53 181.2 11.4 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol3_tau_4 PF12168.3 KNE02667.1 - 0.0035 17.7 1.5 0.0066 16.8 1.1 1.4 1 0 0 1 1 1 1 DNA polymerase III subunits tau domain IV DnaB-binding PBP_sp32 PF07222.7 KNE02667.1 - 0.065 12.3 4.3 0.1 11.7 3.0 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 LAT PF15234.1 KNE02667.1 - 1.4 8.3 5.6 2.8 7.3 3.9 1.5 1 0 0 1 1 1 0 Linker for activation of T-cells Nop14 PF04147.7 KNE02667.1 - 7.7 4.2 15.4 9.6 3.9 10.7 1.1 1 0 0 1 1 1 0 Nop14-like family BLVR PF06375.6 KNE02668.1 - 0.0084 15.9 0.9 0.0084 15.9 0.6 1.0 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) NST1 PF13945.1 KNE02668.1 - 0.06 13.4 2.9 0.061 13.3 2.0 1.0 1 0 0 1 1 1 0 Salt tolerance down-regulator WD40 PF00400.27 KNE02669.1 - 2.4e-23 81.0 2.8 4.1e-07 29.6 0.3 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat PGA2 PF07543.7 KNE02670.1 - 5.3e-09 35.9 16.1 9.8e-07 28.6 11.2 2.1 1 1 0 1 1 1 1 Protein trafficking PGA2 OmpH PF03938.9 KNE02670.1 - 0.00081 19.3 4.6 0.0011 18.9 3.2 1.1 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Ycf1 PF05758.7 KNE02670.1 - 0.025 12.3 1.7 0.025 12.3 1.2 1.1 1 0 0 1 1 1 0 Ycf1 SHR3_chaperone PF08229.6 KNE02670.1 - 0.026 13.4 0.4 0.05 12.5 0.3 1.4 1 0 0 1 1 1 0 ER membrane protein SH3 Phage_Gp23 PF10669.4 KNE02670.1 - 0.058 13.4 1.7 0.076 13.1 1.2 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Amnionless PF14828.1 KNE02670.1 - 0.087 11.3 0.0 0.1 11.0 0.0 1.0 1 0 0 1 1 1 0 Amnionless DivIC PF04977.10 KNE02670.1 - 0.15 11.5 6.2 0.21 11.0 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator Vpu PF00558.14 KNE02670.1 - 0.44 10.1 7.7 0.11 12.0 1.2 2.1 1 1 1 2 2 2 0 Vpu protein Ubiquitin_2 PF14560.1 KNE02671.1 - 1.7e-19 69.8 0.1 3.1e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.20 KNE02671.1 - 1.9e-19 69.1 0.2 2.8e-19 68.5 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain LSM PF01423.17 KNE02672.1 - 8.1e-18 63.7 0.3 1.1e-17 63.2 0.2 1.2 1 0 0 1 1 1 1 LSM domain UPRTase PF14681.1 KNE02673.1 - 4.3e-76 254.7 0.0 5.5e-76 254.3 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KNE02673.1 - 0.0075 15.9 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 KNE02673.1 - 0.07 12.8 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Actin PF00022.14 KNE02674.1 - 1.2e-127 425.5 0.0 1.5e-127 425.3 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KNE02674.1 - 0.023 13.3 0.1 6.9 5.1 0.0 2.6 3 0 0 3 3 3 0 MreB/Mbl protein EF-hand_6 PF13405.1 KNE02675.1 - 0.0041 16.8 0.0 0.05 13.5 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain IL13 PF03487.8 KNE02675.1 - 0.083 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Interleukin-13 RNA_pol_Rpb6 PF01192.17 KNE02676.1 - 5.4e-23 80.5 0.2 8.1e-23 79.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Peptidase_M16 PF00675.15 KNE02677.1 - 4.4e-20 71.9 0.0 7.4e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KNE02677.1 - 3.4e-09 36.6 0.0 7.6e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain PIG-U PF06728.8 KNE02678.1 - 4.8e-100 335.1 32.0 5.5e-100 334.8 22.2 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U LSM PF01423.17 KNE02679.1 - 4.5e-14 51.7 0.2 5.8e-14 51.3 0.2 1.2 1 0 0 1 1 1 1 LSM domain DUF2414 PF10309.4 KNE02680.1 - 1.3e-25 88.8 1.0 2.8e-24 84.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2414) AAA PF00004.24 KNE02681.1 - 9.4e-42 142.3 0.0 1.5e-41 141.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KNE02681.1 - 9.5e-29 99.0 0.2 7e-28 96.3 0.1 2.5 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 KNE02681.1 - 2.6e-20 72.0 3.6 2.6e-20 72.0 2.5 2.0 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 KNE02681.1 - 2.7e-07 31.4 0.2 2.1e-06 28.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KNE02681.1 - 8.1e-07 29.1 0.1 0.02 15.0 0.0 3.7 3 1 1 4 4 4 1 RNA helicase AAA_22 PF13401.1 KNE02681.1 - 6.1e-06 26.4 0.0 0.00062 19.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KNE02681.1 - 1.5e-05 24.7 0.0 0.0002 21.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KNE02681.1 - 2.9e-05 23.2 0.0 4.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KNE02681.1 - 3.7e-05 23.2 0.0 9.2e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KNE02681.1 - 3.9e-05 23.5 0.1 0.0002 21.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KNE02681.1 - 7.1e-05 22.8 0.0 0.0012 18.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 KNE02681.1 - 7.2e-05 21.8 0.0 0.00033 19.6 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 KNE02681.1 - 0.00035 20.0 0.1 0.082 12.2 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 KNE02681.1 - 0.00046 20.0 0.0 0.0012 18.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KNE02681.1 - 0.00052 18.8 0.0 0.00099 17.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 KNE02681.1 - 0.003 17.4 0.0 0.0096 15.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 KNE02681.1 - 0.003 17.8 0.0 0.011 16.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KNE02681.1 - 0.0099 15.6 0.1 0.057 13.1 0.0 2.2 2 1 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 KNE02681.1 - 0.014 14.4 0.1 0.39 9.7 0.0 2.4 1 1 1 2 2 2 0 Zeta toxin AAA_24 PF13479.1 KNE02681.1 - 0.022 14.3 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KNE02681.1 - 0.023 14.1 0.0 0.36 10.2 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 KNE02681.1 - 0.025 13.7 0.0 0.063 12.4 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KNE02681.1 - 0.026 13.6 0.0 4.1 6.4 0.0 2.3 1 1 1 2 2 2 0 KaiC PhoH PF02562.11 KNE02681.1 - 0.035 13.3 0.1 0.092 11.9 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 KNE02681.1 - 0.055 12.3 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Cytidylate_kin2 PF13189.1 KNE02681.1 - 0.057 13.3 0.1 0.13 12.1 0.0 1.7 2 0 0 2 2 1 0 Cytidylate kinase-like family NACHT PF05729.7 KNE02681.1 - 0.057 13.0 0.0 0.87 9.2 0.0 2.4 1 1 1 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 KNE02681.1 - 0.064 12.9 1.3 0.48 10.0 0.0 2.7 2 1 1 3 3 3 0 Archaeal ATPase Torsin PF06309.6 KNE02681.1 - 0.088 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_21 PF13304.1 KNE02681.1 - 0.13 12.1 1.4 3.1 7.6 0.0 2.8 2 1 1 3 3 3 0 AAA domain Ribosomal_S7 PF00177.16 KNE02683.1 - 2.1e-38 131.2 2.9 2.9e-38 130.7 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e OPT PF03169.10 KNE02684.1 - 5.2e-180 599.9 42.7 6.3e-180 599.6 29.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1700 PF08006.6 KNE02689.1 - 0.09 12.0 0.4 0.1 11.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) GST_C PF00043.20 KNE02691.1 - 1.5e-08 34.5 0.0 5e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KNE02691.1 - 1.7e-05 24.5 0.0 2.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KNE02691.1 - 2.3e-05 24.8 0.0 2.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pyridox_oxidase PF01243.15 KNE02692.1 - 3.1e-13 49.5 0.1 2.5e-12 46.6 0.0 2.3 2 1 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 KNE02692.1 - 0.00089 19.1 0.0 0.0071 16.1 0.0 2.1 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_oxidase_2 PF13883.1 KNE02692.1 - 0.024 14.4 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Pectate_lyase22 PF14583.1 KNE02692.1 - 0.055 11.9 0.0 0.076 11.4 0.0 1.2 1 0 0 1 1 1 0 Oligogalacturonate lyase ORC4_C PF14629.1 KNE02694.1 - 8.8e-38 129.7 1.5 1.8e-37 128.7 1.1 1.5 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 KNE02694.1 - 2.6e-15 56.8 0.0 6.8e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KNE02694.1 - 1.4e-12 47.8 0.1 4.4e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KNE02694.1 - 1.3e-07 31.8 0.1 3.6e-07 30.4 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KNE02694.1 - 4.8e-07 29.7 0.1 1.2e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Archaeal ATPase AAA_5 PF07728.9 KNE02694.1 - 0.00015 21.4 0.1 0.00072 19.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KNE02694.1 - 0.00036 20.4 0.2 0.016 15.0 0.1 3.2 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.4 KNE02694.1 - 0.0012 17.8 0.0 0.0022 17.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PTS_IIB PF02302.12 KNE02694.1 - 0.0012 19.2 0.0 0.78 10.2 0.0 3.5 3 0 0 3 3 3 1 PTS system, Lactose/Cellobiose specific IIB subunit KAP_NTPase PF07693.9 KNE02694.1 - 0.0031 16.5 0.0 0.82 8.5 0.0 2.6 1 1 1 2 2 2 2 KAP family P-loop domain ABC_tran PF00005.22 KNE02694.1 - 0.039 14.2 0.1 0.89 9.8 0.0 2.6 2 0 0 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.13 KNE02694.1 - 0.043 13.2 0.2 0.45 9.9 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Helicase_RecD PF05127.9 KNE02694.1 - 0.07 12.7 0.1 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 Helicase Sigma54_activat PF00158.21 KNE02694.1 - 0.095 12.1 0.0 0.36 10.2 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain RGS PF00615.14 KNE02695.1 - 1.7e-13 50.7 0.0 1.9e-12 47.3 0.0 2.6 1 1 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 KNE02695.1 - 6.5e-13 48.2 0.1 2.1e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) GTP_EFTU PF00009.22 KNE02696.1 - 2.5e-38 131.3 0.0 4.1e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 KNE02696.1 - 6.3e-35 119.1 0.2 1.3e-34 118.0 0.1 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 KNE02696.1 - 1.4e-11 44.3 1.6 3e-11 43.2 0.4 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KNE02696.1 - 0.0055 16.6 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KNE02696.1 - 0.12 12.1 0.2 1 9.1 0.0 2.4 3 0 0 3 3 3 0 Dynamin family Exo_endo_phos PF03372.18 KNE02697.1 - 9.5e-10 38.8 0.0 1.4e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KNE02697.1 - 0.044 13.3 0.0 0.12 12.0 0.0 1.8 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Rad17 PF03215.10 KNE02698.1 - 3e-11 42.6 0.1 2.1e-07 30.0 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA PF00004.24 KNE02698.1 - 4.4e-10 39.8 0.0 1.2e-09 38.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KNE02698.1 - 7.5e-08 32.5 0.0 2.1e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KNE02698.1 - 6e-07 29.6 1.1 6.2e-05 23.0 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 KNE02698.1 - 5.1e-05 24.0 1.5 0.00023 21.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KNE02698.1 - 0.00018 21.4 0.0 0.00063 19.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KNE02698.1 - 0.00038 20.0 4.6 0.00091 18.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KNE02698.1 - 0.00077 18.6 0.0 0.0024 17.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KNE02698.1 - 0.0064 16.3 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KNE02698.1 - 0.02 14.6 0.0 0.064 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KNE02698.1 - 0.024 14.8 0.0 0.5 10.5 0.0 2.9 3 0 0 3 3 3 0 RNA helicase AAA_19 PF13245.1 KNE02698.1 - 0.025 14.3 0.1 0.09 12.5 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain DUF1712 PF08217.6 KNE02699.1 - 3.1e-17 62.0 4.5 1.7e-12 46.4 0.1 3.5 3 1 0 3 3 3 3 Fungal domain of unknown function (DUF1712) LAGLIDADG_1 PF00961.14 KNE02699.1 - 0.036 14.6 1.0 0.11 13.0 0.7 1.8 1 0 0 1 1 1 0 LAGLIDADG endonuclease DUF3074 PF11274.3 KNE02700.1 - 3.2e-30 105.1 0.0 4.2e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) START PF01852.14 KNE02700.1 - 0.027 13.7 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 START domain zf-MYND PF01753.13 KNE02701.1 - 6.4e-07 29.1 20.3 1.4e-06 28.0 14.1 1.6 1 0 0 1 1 1 1 MYND finger Zip PF02535.17 KNE02701.1 - 0.0096 14.9 1.7 0.015 14.3 1.2 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Peptidase_C50 PF03568.12 KNE02702.1 - 3.6e-79 266.2 1.7 7.9e-79 265.0 0.0 2.4 2 1 0 2 2 2 1 Peptidase family C50 Flavin_Reduct PF01613.13 KNE02703.1 - 2.6e-26 92.3 0.1 3.2e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Filament PF00038.16 KNE02704.1 - 0.0071 15.8 20.0 0.1 12.0 8.7 2.3 2 0 0 2 2 2 2 Intermediate filament protein DUF3450 PF11932.3 KNE02704.1 - 0.014 14.7 16.0 0.022 14.0 2.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF2053 PF09767.4 KNE02704.1 - 0.018 15.0 1.5 0.041 13.8 1.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2053) COG5 PF10392.4 KNE02704.1 - 0.17 11.8 15.9 0.057 13.3 3.0 3.1 2 1 1 3 3 3 0 Golgi transport complex subunit 5 DivIC PF04977.10 KNE02704.1 - 0.4 10.1 23.2 0.52 9.8 2.4 4.2 2 1 2 4 4 4 0 Septum formation initiator AAA_13 PF13166.1 KNE02704.1 - 0.56 8.6 17.0 1.8 6.9 11.8 1.7 1 1 0 1 1 1 0 AAA domain DUF948 PF06103.6 KNE02704.1 - 0.6 10.0 11.3 2.3 8.1 0.2 4.2 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.4 KNE02704.1 - 0.86 8.4 27.3 0.02 13.8 11.1 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 KNE02704.1 - 1.4 8.7 26.0 2.8 7.8 0.4 4.5 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 KNE02704.1 - 2.1 8.7 18.6 3.2 8.1 3.5 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF4407 PF14362.1 KNE02704.1 - 3 6.7 11.6 0.67 8.8 4.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Med9 PF07544.8 KNE02704.1 - 3.1 7.5 12.7 0.34 10.6 2.9 2.9 2 2 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ADIP PF11559.3 KNE02704.1 - 4.4 7.2 30.5 0.6 10.0 3.6 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.7 KNE02704.1 - 5 7.4 8.9 2.2 8.5 1.5 3.3 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein Snapin_Pallidin PF14712.1 KNE02704.1 - 5.5 7.3 18.6 1.8 8.9 0.8 3.6 3 1 0 3 3 3 0 Snapin/Pallidin FlaC_arch PF05377.6 KNE02704.1 - 6 6.8 16.4 15 5.5 0.6 4.4 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) IncA PF04156.9 KNE02704.1 - 7.7 6.0 29.5 0.63 9.6 6.6 2.8 1 1 1 2 2 2 0 IncA protein DUF2401 PF10287.4 KNE02706.1 - 2.2e-88 295.7 1.8 3.4e-88 295.1 1.2 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 KNE02706.1 - 2e-22 79.1 0.7 5.3e-22 77.7 0.0 2.0 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) DUF3591 PF12157.3 KNE02707.1 - 0.12 10.6 0.0 0.17 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3591) FtsJ PF01728.14 KNE02708.1 - 7.2e-57 192.2 0.0 8.3e-57 192.0 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 KNE02708.1 - 0.0061 16.1 0.0 0.024 14.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNE02708.1 - 0.031 14.8 0.0 0.058 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KNE02708.1 - 0.032 13.9 0.0 0.059 13.0 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain DUF2403 PF10290.4 KNE02708.1 - 0.1 12.8 0.1 0.72 10.0 0.0 2.1 2 0 0 2 2 2 0 Glycine-rich protein domain (DUF2403) Methyltrans_Mon PF14314.1 KNE02708.1 - 0.13 10.0 0.0 0.16 9.7 0.0 1.1 1 0 0 1 1 1 0 Virus-capping methyltransferase Mpp10 PF04006.7 KNE02709.1 - 1.9e-99 333.7 64.6 3.6e-99 332.8 44.8 1.4 1 1 0 1 1 1 1 Mpp10 protein DUF972 PF06156.8 KNE02709.1 - 0.49 10.7 0.1 0.49 10.7 0.0 4.9 4 1 0 4 4 4 0 Protein of unknown function (DUF972) Metal_resist PF13801.1 KNE02709.1 - 2.3 8.2 6.0 2 8.4 0.6 2.5 2 0 0 2 2 2 0 Heavy-metal resistance DUF2424 PF10340.4 KNE02714.1 - 7.8e-17 60.9 0.0 4.4e-16 58.4 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 KNE02714.1 - 1.6e-12 47.4 0.1 2.3e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF4525 PF15027.1 KNE02715.1 - 0.026 14.0 0.0 0.027 14.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) MFS_1 PF07690.11 KNE02716.1 - 2.3e-14 52.8 44.7 2.6e-11 42.8 17.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KNE02716.1 - 0.00011 20.5 23.1 0.00016 20.0 16.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Tmemb_18A PF09771.4 KNE02716.1 - 0.011 15.6 0.2 0.071 13.0 0.1 2.4 1 0 0 1 1 1 0 Transmembrane protein 188 DUF2424 PF10340.4 KNE02718.1 - 2.4e-18 65.9 0.0 8.8e-18 64.0 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 KNE02718.1 - 1.3e-09 38.0 0.1 2.7e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNE02718.1 - 0.0055 16.4 0.0 0.0089 15.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3671 PF12420.3 KNE02720.1 - 0.025 14.5 1.0 0.033 14.1 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF3753 PF12575.3 KNE02720.1 - 0.03 14.0 0.2 0.036 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) ETRAMP PF09716.5 KNE02720.1 - 8.3 6.4 7.1 2 8.4 1.5 2.0 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) PIR PF00399.14 KNE02721.1 - 4e-20 70.3 114.6 1.7e-05 23.9 0.8 11.1 10 1 0 10 10 10 10 Yeast PIR protein repeat Med15 PF09606.5 KNE02721.1 - 0.18 9.9 44.5 0.24 9.5 30.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Asp PF00026.18 KNE02722.1 - 1e-43 149.7 0.4 6.7e-43 147.1 0.2 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KNE02722.1 - 1.7e-06 28.0 0.0 1.7e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KNE02722.1 - 0.019 14.4 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal HPP PF04982.8 KNE02723.1 - 8.2e-36 122.4 5.6 8.2e-36 122.4 3.9 1.6 2 0 0 2 2 2 1 HPP family TMEM190 PF15431.1 KNE02723.1 - 0.1 12.5 0.2 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 190 Cation_ATPase_C PF00689.16 KNE02723.1 - 0.18 11.3 2.2 0.42 10.1 0.6 2.2 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus DUF2427 PF10348.4 KNE02723.1 - 0.3 10.6 5.1 1.5 8.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) Frag1 PF10277.4 KNE02724.1 - 3.5e-52 177.0 27.2 4.2e-52 176.7 18.8 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Picorna_P3A PF06363.6 KNE02724.1 - 0.032 14.2 0.1 0.12 12.3 0.1 1.9 1 0 0 1 1 1 0 Picornaviridae P3A protein Tetraspannin PF00335.15 KNE02724.1 - 4.7 6.4 16.1 0.017 14.4 4.2 2.0 2 1 0 2 2 2 0 Tetraspanin family RNB PF00773.14 KNE02725.1 - 4.3e-94 315.4 0.0 7e-94 314.7 0.0 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 KNE02725.1 - 1.1e-14 54.6 1.0 3.2e-14 53.1 0.7 1.8 1 0 0 1 1 1 1 PIN domain OB_RNB PF08206.6 KNE02725.1 - 0.0042 16.5 0.1 0.026 14.0 0.0 2.3 2 0 0 2 2 2 1 Ribonuclease B OB domain DHBP_synthase PF00926.14 KNE02726.1 - 4.8e-83 277.1 0.1 5.3e-83 277.0 0.1 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase DUF4373 PF14297.1 KNE02726.1 - 0.031 14.5 0.0 0.065 13.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4373) GIDE PF12483.3 KNE02726.1 - 0.1 11.9 0.0 0.9 8.8 0.0 2.0 2 0 0 2 2 2 0 E3 Ubiquitin ligase chaperone_DMP PF10448.4 KNE02727.1 - 2.5e-21 76.0 0.0 2.9e-21 75.8 0.0 1.0 1 0 0 1 1 1 1 20S proteasome chaperone tRNA-synt_1b PF00579.20 KNE02728.1 - 7.6e-19 67.9 0.0 1.2e-12 47.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Ribosomal_L27e PF01777.13 KNE02730.1 - 1.1e-19 70.3 0.8 1.2e-19 70.2 0.5 1.0 1 0 0 1 1 1 1 Ribosomal L27e protein family SMN PF06003.7 KNE02730.1 - 0.038 13.0 0.2 0.044 12.8 0.1 1.0 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Hydrolase_2 PF07486.7 KNE02730.1 - 0.13 12.8 0.1 0.14 12.6 0.1 1.1 1 0 0 1 1 1 0 Cell Wall Hydrolase Pkinase PF00069.20 KNE02731.1 - 8e-64 215.2 0.0 1.2e-63 214.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNE02731.1 - 1.2e-30 106.4 0.0 1.9e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNE02731.1 - 9.2e-06 24.8 0.0 2.7e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KNE02731.1 - 0.0039 16.2 0.0 0.0068 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KNE02731.1 - 0.09 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.11 KNE02732.1 - 9.9e-10 37.6 41.5 8.7e-06 24.6 16.1 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KNE02732.1 - 8.8e-09 34.0 22.1 9.3e-08 30.7 7.1 2.3 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) PetG PF02529.10 KNE02732.1 - 0.39 10.2 4.0 0.43 10.1 0.3 2.6 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 EAP30 PF04157.11 KNE02733.1 - 0.00079 18.6 0.3 0.046 12.8 0.0 2.6 2 0 0 2 2 2 2 EAP30/Vps36 family RA PF00788.18 KNE02733.1 - 0.017 15.6 0.1 4.9 7.7 0.0 3.2 3 0 0 3 3 3 0 Ras association (RalGDS/AF-6) domain RNase_T PF00929.19 KNE02735.1 - 8.4e-23 81.4 0.0 1.1e-22 81.0 0.0 1.1 1 0 0 1 1 1 1 Exonuclease RasGAP PF00616.14 KNE02736.1 - 6e-35 120.7 1.4 6e-35 120.7 1.0 3.3 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RIIa PF02197.12 KNE02738.1 - 0.15 11.5 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit DUF2611 PF11022.3 KNE02739.1 - 6.9e-28 96.5 0.0 7.4e-28 96.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) Brix PF04427.13 KNE02740.1 - 4.9e-43 147.0 1.0 6.2e-43 146.6 0.7 1.1 1 0 0 1 1 1 1 Brix domain E2F_TDP PF02319.15 KNE02741.1 - 0.054 13.0 0.0 0.054 13.0 0.0 1.1 1 0 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain Rhomboid PF01694.17 KNE02742.1 - 1.8e-33 115.6 13.4 1.8e-33 115.6 9.3 1.9 2 0 0 2 2 2 1 Rhomboid family E1-E2_ATPase PF00122.15 KNE02742.1 - 0.058 12.4 0.0 0.2 10.6 0.0 1.9 2 0 0 2 2 2 0 E1-E2 ATPase DUF3746 PF12562.3 KNE02746.1 - 0.036 13.9 1.8 0.16 11.8 1.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3746) DUF29 PF01724.11 KNE02747.1 - 0.086 12.6 0.1 0.086 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF29 Ribosomal_L50 PF10501.4 KNE02749.1 - 2.9e-22 78.7 0.0 5.3e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S AIP3 PF03915.8 KNE02749.1 - 0.0057 15.6 0.1 0.0081 15.1 0.1 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 Cytokin_check_N PF10407.4 KNE02749.1 - 0.025 14.1 0.1 0.17 11.5 0.0 2.2 1 1 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus OTCace PF00185.19 KNE02749.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain PYRIN PF02758.11 KNE02749.1 - 0.44 10.2 3.9 1.6 8.4 0.0 2.8 3 0 0 3 3 3 0 PAAD/DAPIN/Pyrin domain CBS PF00571.23 KNE02750.1 - 2.3e-39 132.9 8.5 2.8e-11 43.0 0.0 5.9 6 0 0 6 6 6 4 CBS domain PB1 PF00564.19 KNE02750.1 - 2.9e-11 42.8 0.3 5.8e-11 41.8 0.2 1.5 1 0 0 1 1 1 1 PB1 domain Prenyltransf PF01255.14 KNE02752.1 - 8.2e-08 31.6 0.0 1e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Prenyltransf PF01255.14 KNE02753.1 - 1.7e-40 138.5 0.0 2e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Vma12 PF11712.3 KNE02754.1 - 9.2e-39 132.3 0.1 1.4e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DnaG_DnaB_bind PF08278.6 KNE02754.1 - 0.0022 18.1 4.0 0.12 12.5 0.2 2.3 1 1 1 2 2 2 2 DNA primase DnaG DnaB-binding ATP_synt_I PF03899.10 KNE02754.1 - 0.017 15.2 0.4 0.03 14.4 0.3 1.4 1 0 0 1 1 1 0 ATP synthase I chain Cyt_c_ox_IV PF12270.3 KNE02754.1 - 0.03 14.0 0.4 0.048 13.4 0.3 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV DUF2385 PF09539.5 KNE02754.1 - 0.093 13.1 0.2 1.1 9.7 0.0 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2385) tRNA_SAD PF07973.9 KNE02755.1 - 1.4e-12 47.2 0.2 3.4e-12 46.0 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 KNE02755.1 - 1.4e-09 36.8 0.1 5.3e-09 34.9 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (A) TSC22 PF01166.13 KNE02755.1 - 0.043 13.7 0.1 0.2 11.6 0.1 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family Ribosomal_S9 PF00380.14 KNE02756.1 - 2.1e-40 137.7 0.2 3.5e-40 137.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Myb_DNA-binding PF00249.26 KNE02757.1 - 7.9e-12 45.0 0.0 6.6e-06 26.0 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KNE02757.1 - 1.9e-05 24.6 4.0 0.0053 16.8 0.1 3.7 3 0 0 3 3 3 1 Myb-like DNA-binding domain Pox_A14 PF05767.7 KNE02758.1 - 0.093 12.7 0.8 0.12 12.3 0.4 1.4 1 1 0 1 1 1 0 Poxvirus virion envelope protein A14 AAA_16 PF13191.1 KNE02759.1 - 1.4e-09 38.2 0.1 6.8e-08 32.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.24 KNE02759.1 - 3.5e-08 33.7 0.0 1.6e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KNE02759.1 - 3.5e-08 33.6 0.0 8.3e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KNE02759.1 - 0.00013 21.6 0.0 0.013 15.2 0.0 3.0 3 0 0 3 3 3 1 Part of AAA domain Arch_ATPase PF01637.13 KNE02759.1 - 0.00032 20.4 0.0 0.00069 19.3 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase T2SE PF00437.15 KNE02759.1 - 0.0028 16.6 0.2 0.013 14.4 0.0 2.1 3 0 0 3 3 3 1 Type II/IV secretion system protein CENP-S PF15630.1 KNE02760.1 - 6.7e-29 99.8 0.1 8.7e-29 99.5 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 KNE02760.1 - 0.00012 21.5 0.0 0.00016 21.0 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Histone PF00125.19 KNE02760.1 - 0.023 14.8 0.1 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF3610 PF12272.3 KNE02760.1 - 0.046 13.3 0.0 0.076 12.6 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3610) TFIID-18kDa PF02269.11 KNE02760.1 - 0.048 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF3337 PF11816.3 KNE02761.1 - 2.1e-62 211.4 3.2 2.1e-62 211.4 2.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.27 KNE02761.1 - 4.5e-20 70.7 7.3 5.5e-08 32.3 0.0 6.9 8 0 0 8 8 8 3 WD domain, G-beta repeat RNA_pol_Rpb5_C PF01191.14 KNE02762.1 - 1.1e-33 114.6 0.5 1.8e-33 113.9 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KNE02762.1 - 2.6e-30 104.6 0.1 4.1e-30 104.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain SH3_2 PF07653.12 KNE02762.1 - 0.07 12.6 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain DUF3648 PF12364.3 KNE02762.1 - 0.085 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3648) RibD_C PF01872.12 KNE02763.1 - 2.2e-32 112.2 0.0 2.7e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain ELO PF01151.13 KNE02765.1 - 1.8e-60 204.3 24.0 2.2e-60 204.0 16.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family PfkB PF00294.19 KNE02767.1 - 5.5e-48 163.6 2.3 7.3e-48 163.2 1.6 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Peptidase_S15 PF02129.13 KNE02767.1 - 0.036 13.4 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) FtsH_ext PF06480.10 KNE02767.1 - 0.037 14.2 0.3 12 6.1 0.0 2.5 2 0 0 2 2 2 0 FtsH Extracellular PCI PF01399.22 KNE02768.1 - 2.5e-10 40.6 0.3 1.3e-09 38.3 0.2 2.4 1 0 0 1 1 1 1 PCI domain BCIP PF13862.1 KNE02770.1 - 9.6e-66 220.9 2.7 1.3e-65 220.5 1.9 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein UCH_1 PF13423.1 KNE02771.1 - 6.3e-53 180.1 0.6 1.4e-52 179.0 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 KNE02771.1 - 2.6e-15 56.2 0.1 5e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Dicty_CAD PF05720.7 KNE02771.1 - 0.35 10.5 1.8 9.7 5.9 0.0 3.3 4 0 0 4 4 4 0 Cell-cell adhesion domain BAR PF03114.13 KNE02773.1 - 2.5e-37 128.6 8.7 3.4e-37 128.1 6.0 1.2 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 KNE02773.1 - 6.4e-08 32.2 6.2 1.1e-07 31.4 4.3 1.4 1 1 0 1 1 1 1 Arfaptin-like domain BBE PF08031.7 KNE02773.1 - 0.019 14.8 0.0 0.048 13.5 0.0 1.8 1 0 0 1 1 1 0 Berberine and berberine like PolyA_pol PF01743.15 KNE02773.1 - 0.14 12.3 1.6 0.23 11.6 0.0 2.1 3 0 0 3 3 3 0 Poly A polymerase head domain Ribosomal_S30AE PF02482.14 KNE02773.1 - 0.22 11.9 4.1 0.6 10.5 0.1 3.3 2 1 1 3 3 3 0 Sigma 54 modulation protein / S30EA ribosomal protein HTH_Tnp_IS630 PF01710.11 KNE02773.1 - 0.48 10.0 4.2 0.11 12.2 0.2 1.9 2 0 0 2 2 2 0 Transposase Mt_ATP-synt_B PF05405.9 KNE02773.1 - 1 8.8 8.3 0.9 8.9 0.1 2.9 3 0 0 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) AMPKBI PF04739.10 KNE02774.1 - 1.6e-38 130.6 6.4 9.1e-38 128.1 4.4 2.3 1 1 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain TDH PF03347.8 KNE02774.1 - 0.48 9.9 3.1 0.57 9.7 0.1 2.4 3 0 0 3 3 3 0 Vibrio thermostable direct hemolysin zf-HC5HC2H_2 PF13832.1 KNE02778.1 - 1e-31 109.1 18.2 5e-31 106.9 5.0 3.3 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KNE02778.1 - 6.3e-27 93.5 6.1 6.3e-27 93.5 4.2 4.4 4 0 0 4 4 4 1 PHD-like zinc-binding domain PHD_2 PF13831.1 KNE02778.1 - 5.7e-14 51.1 1.8 5.7e-14 51.1 1.2 2.7 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 KNE02778.1 - 1.1e-09 37.8 5.9 1.1e-09 37.8 4.1 2.9 2 0 0 2 2 2 1 PHD-finger EPL1 PF10513.4 KNE02778.1 - 2.9e-06 27.6 0.0 5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Enhancer of polycomb-like C1_1 PF00130.17 KNE02778.1 - 0.0029 17.3 2.7 0.0029 17.3 1.9 3.0 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KNE02778.1 - 0.15 11.8 17.2 0.036 13.7 1.7 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 KNE02778.1 - 0.21 11.6 24.1 0.27 11.2 5.7 2.9 2 1 0 2 2 2 0 RING-like domain FYVE_2 PF02318.11 KNE02778.1 - 1.1 9.1 10.6 0.081 12.8 1.0 2.8 2 0 0 2 2 2 0 FYVE-type zinc finger DNAPolymera_Pol PF11590.3 KNE02781.1 - 0.02 14.5 0.3 0.037 13.7 0.1 1.7 2 0 0 2 2 2 0 DNA polymerase catalytic subunit Pol TEA PF01285.13 KNE02782.1 - 2e-27 96.4 0.2 3.3e-27 95.7 0.1 1.3 1 0 0 1 1 1 1 TEA/ATTS domain family ATP-grasp PF02222.17 KNE02783.1 - 1.1e-63 213.6 0.0 1.8e-63 212.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain AIRC PF00731.15 KNE02783.1 - 1.7e-63 212.4 2.6 2.2e-63 212.0 1.0 1.8 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp_4 PF13535.1 KNE02783.1 - 1.7e-11 44.2 0.0 3.1e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KNE02783.1 - 2.5e-07 30.1 0.0 4.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain 2-Hacid_dh_C PF02826.14 KNE02783.1 - 0.00013 21.1 0.1 0.00031 19.9 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dala_Dala_lig_C PF07478.8 KNE02783.1 - 0.005 16.2 0.0 0.14 11.4 0.0 2.4 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus PhoU_div PF01865.11 KNE02783.1 - 0.051 12.7 0.1 0.11 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF47 NPV_P10 PF05531.7 KNE02783.1 - 0.066 13.4 0.2 0.21 11.8 0.1 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein F420_oxidored PF03807.12 KNE02783.1 - 0.067 13.6 0.2 0.73 10.3 0.0 2.7 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent CoA_binding_2 PF13380.1 KNE02783.1 - 0.079 13.1 1.8 34 4.6 0.1 4.0 4 1 0 5 5 5 0 CoA binding domain TrkA_N PF02254.13 KNE02783.1 - 0.088 12.8 0.2 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain ATP-grasp_3 PF02655.9 KNE02783.1 - 0.097 12.5 0.0 0.45 10.3 0.0 2.3 2 1 0 2 2 2 0 ATP-grasp domain DUF2423 PF10338.4 KNE02784.1 - 1.5e-15 56.8 10.9 1.5e-15 56.8 7.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) MCM2_N PF12619.3 KNE02784.1 - 0.039 13.9 2.4 0.05 13.5 1.7 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 D123 PF07065.9 KNE02784.1 - 0.17 10.9 0.9 0.18 10.8 0.6 1.0 1 0 0 1 1 1 0 D123 DUF4139 PF13598.1 KNE02784.1 - 0.2 10.9 2.2 0.21 10.8 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) bZIP_Maf PF03131.12 KNE02785.1 - 0.0049 17.1 2.1 0.0049 17.1 1.5 1.0 1 0 0 1 1 1 1 bZIP Maf transcription factor Ribosomal_L19e PF01280.15 KNE02786.1 - 3.9e-31 107.8 5.4 3.9e-31 107.8 3.7 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e Serendipity_A PF05482.7 KNE02786.1 - 0.13 10.6 1.5 0.14 10.5 1.1 1.0 1 0 0 1 1 1 0 Serendipity locus alpha protein (SRY-A) Alpha_TIF PF02232.10 KNE02786.1 - 3.2 6.4 6.4 0.42 9.3 0.7 1.9 1 1 1 2 2 2 0 Alpha trans-inducing protein (Alpha-TIF) RGS PF00615.14 KNE02787.1 - 6.4e-06 26.2 0.2 8.5e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 Regulator of G protein signaling domain CTK3 PF12243.3 KNE02788.1 - 0.096 12.3 0.1 0.1 12.2 0.1 1.1 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 zf-C2H2 PF00096.21 KNE02793.1 - 8.4e-05 22.6 1.3 8.4e-05 22.6 0.9 3.8 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNE02793.1 - 0.022 15.0 1.1 0.022 15.0 0.8 3.7 3 2 1 4 4 4 0 C2H2-type zinc finger HypA PF01155.14 KNE02793.1 - 0.058 13.0 3.1 1.4 8.6 0.1 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family LIM PF00412.17 KNE02793.1 - 0.088 12.8 3.8 4.5 7.4 0.1 2.4 2 0 0 2 2 2 0 LIM domain Zn_Tnp_IS1595 PF12760.2 KNE02793.1 - 0.45 10.3 3.8 6.2 6.7 0.2 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Tmemb_55A PF09788.4 KNE02793.1 - 1.2 8.2 4.2 0.54 9.3 0.1 2.1 2 1 0 3 3 3 0 Transmembrane protein 55A C1_4 PF07975.7 KNE02793.1 - 1.6 8.8 7.6 12 6.0 0.7 2.9 2 1 1 3 3 3 0 TFIIH C1-like domain zf-H2C2_2 PF13465.1 KNE02793.1 - 3.1 8.2 12.7 1.8 8.9 0.1 3.7 4 0 0 4 4 4 0 Zinc-finger double domain zinc_ribbon_5 PF13719.1 KNE02793.1 - 5.9 6.5 6.7 2.3 7.8 0.0 2.9 3 0 0 3 3 3 0 zinc-ribbon domain DUF2205 PF10224.4 KNE02796.1 - 2.5e-05 23.7 1.9 2.6e-05 23.7 1.3 1.0 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) HAP1_N PF04849.8 KNE02796.1 - 0.0041 16.1 1.7 0.0041 16.1 1.2 1.0 1 0 0 1 1 1 1 HAP1 N-terminal conserved region MRP-S31 PF15433.1 KNE02797.1 - 0.11 11.8 0.9 0.13 11.6 0.7 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 FoP_duplication PF13865.1 KNE02798.1 - 3.4e-05 24.1 3.8 6e-05 23.4 2.6 1.5 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 KNE02798.1 - 0.00033 20.4 0.1 0.00055 19.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNE02798.1 - 0.00072 19.4 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KNE02798.1 - 0.00074 19.1 0.1 0.0018 17.8 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phlebovirus_NSM PF07246.6 KNE02798.1 - 0.0079 15.3 2.9 0.0076 15.4 2.0 1.2 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M RE_TdeIII PF09520.5 KNE02798.1 - 0.018 14.3 2.6 0.029 13.6 1.8 1.3 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII DUF3878 PF12994.2 KNE02798.1 - 0.084 12.0 2.1 0.098 11.8 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3878) RRM_3 PF08777.6 KNE02798.1 - 0.38 10.6 0.1 0.38 10.6 0.0 2.2 1 1 1 2 2 2 0 RNA binding motif DUF106 PF01956.11 KNE02798.1 - 1.3 8.5 7.0 1.9 7.9 4.9 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF3896 PF13035.1 KNE02798.1 - 2.1 8.4 5.9 5.2 7.2 4.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) SPA PF08616.5 KNE02799.1 - 1.3e-33 115.1 0.2 3.3e-33 113.7 0.0 1.8 2 0 0 2 2 2 1 Stabilization of polarity axis Afi1 PF07792.7 KNE02799.1 - 5.9e-29 100.9 0.0 1.1e-28 100.0 0.0 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.4 KNE02799.1 - 2.4e-14 52.6 0.3 5.9e-10 38.1 0.0 2.4 2 0 0 2 2 2 2 Transport protein Avl9 DENN PF02141.16 KNE02799.1 - 0.00033 20.4 1.0 0.33 10.6 0.0 2.7 3 0 0 3 3 3 2 DENN (AEX-3) domain DUF1505 PF07403.6 KNE02799.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) Acyltransferase PF01553.16 KNE02802.1 - 3.5e-32 110.6 0.0 6.4e-32 109.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Fijivirus_P9-2 PF06837.6 KNE02803.1 - 4 6.4 6.4 4 6.5 4.5 1.1 1 0 0 1 1 1 0 Fijivirus P9-2 protein GIT_SHD PF08518.6 KNE02804.1 - 4.3e-22 77.1 6.2 5e-11 41.7 1.5 2.9 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT TSC22 PF01166.13 KNE02804.1 - 0.35 10.8 8.8 7.9 6.5 0.1 4.1 3 0 0 3 3 3 0 TSC-22/dip/bun family Cwf_Cwc_15 PF04889.7 KNE02805.1 - 6.3e-17 62.1 14.0 4.3e-10 39.7 5.8 2.0 1 1 1 2 2 2 2 Cwf15/Cwc15 cell cycle control protein TPR_11 PF13414.1 KNE02806.1 - 1.2e-08 34.4 3.0 0.00048 19.7 0.1 3.4 3 1 1 4 4 4 3 TPR repeat TPR_19 PF14559.1 KNE02806.1 - 1.1e-05 25.6 13.1 0.00023 21.4 0.2 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 KNE02806.1 - 1.2e-05 24.8 3.8 0.1 12.5 0.0 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KNE02806.1 - 1.7e-05 25.3 4.8 0.0075 16.9 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KNE02806.1 - 2.6e-05 24.2 4.5 0.0052 16.9 0.0 3.4 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KNE02806.1 - 6.8e-05 22.7 4.7 0.12 12.2 0.1 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KNE02806.1 - 0.00026 20.4 0.5 1.4 8.6 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KNE02806.1 - 0.00071 19.1 0.1 0.056 13.2 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KNE02806.1 - 0.0012 19.2 7.6 0.73 10.6 0.0 5.2 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 KNE02806.1 - 0.0079 16.3 0.2 1.4 9.3 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat ChAPs PF09295.5 KNE02806.1 - 0.013 14.2 0.1 0.03 13.1 0.0 1.5 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.1 KNE02806.1 - 0.042 14.2 3.9 6.6 7.4 0.0 3.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KNE02806.1 - 0.056 13.2 0.5 4 7.4 0.1 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_21 PF09976.4 KNE02806.1 - 0.067 13.1 10.7 0.69 9.8 0.1 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat YfdX PF10938.3 KNE02806.1 - 5.4 6.6 7.2 4.2 7.0 0.3 3.2 3 0 0 3 3 3 0 YfdX protein DUF4477 PF14780.1 KNE02807.1 - 0.0081 15.5 0.8 0.91 8.8 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4477) SCIMP PF15050.1 KNE02807.1 - 0.062 13.2 0.1 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 SCIMP protein DUF3899 PF13038.1 KNE02807.1 - 0.19 11.9 4.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) zf-H2C2_2 PF13465.1 KNE02808.1 - 3.9e-06 26.8 8.9 0.0012 19.0 0.5 4.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KNE02808.1 - 0.00057 20.0 6.9 0.00057 20.0 4.8 3.3 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNE02808.1 - 0.0071 16.6 15.6 0.013 15.7 2.2 3.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-Di19 PF05605.7 KNE02808.1 - 2.5 8.3 8.4 2 8.5 3.6 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Spermine_synth PF01564.12 KNE02811.1 - 2.2e-53 180.6 0.1 3.1e-53 180.2 0.1 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 KNE02811.1 - 0.008 16.7 0.0 0.015 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 KNE02811.1 - 0.018 13.9 0.4 0.031 13.2 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF43 Methyltransf_3 PF01596.12 KNE02811.1 - 0.04 12.9 0.1 0.061 12.3 0.1 1.3 1 0 0 1 1 1 0 O-methyltransferase NAD_binding_7 PF13241.1 KNE02811.1 - 0.052 13.8 0.2 0.17 12.1 0.1 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding Foamy_BEL PF03274.9 KNE02811.1 - 0.086 12.0 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Foamy virus BEL 1/2 protein DcpS_C PF11969.3 KNE02811.1 - 0.11 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding AFT PF08731.6 KNE02813.1 - 6.9e-08 32.6 0.1 6.9e-08 32.6 0.1 2.2 3 0 0 3 3 3 1 Transcription factor AFT DBD_Tnp_Mut PF03108.10 KNE02813.1 - 0.0014 18.1 0.1 0.056 13.0 0.0 2.4 2 0 0 2 2 2 1 MuDR family transposase FAR1 PF03101.10 KNE02813.1 - 0.0034 17.8 3.4 0.0034 17.8 2.3 2.6 2 1 0 2 2 2 1 FAR1 DNA-binding domain OmpH PF03938.9 KNE02813.1 - 0.1 12.5 9.8 0.14 12.0 2.3 3.2 2 2 0 2 2 2 0 Outer membrane protein (OmpH-like) CRAL_TRIO_2 PF13716.1 KNE02815.1 - 7.7e-30 103.7 1.7 1.8e-29 102.5 1.1 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 KNE02815.1 - 0.00029 20.4 0.0 0.00065 19.3 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain RB_B PF01857.15 KNE02815.1 - 0.082 12.4 0.4 3.8 6.9 0.1 2.5 2 0 0 2 2 2 0 Retinoblastoma-associated protein B domain P53_C PF11619.3 KNE02816.1 - 0.027 14.2 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain DASH_Dad1 PF08649.5 KNE02818.1 - 1.4e-27 95.1 0.1 1.7e-27 94.8 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 AMP-binding PF00501.23 KNE02819.1 - 0.0022 16.4 0.0 0.16 10.3 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Imm47 PF15586.1 KNE02819.1 - 0.0087 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Immunity protein 47 Metallophos PF00149.23 KNE02820.1 - 1.9e-13 50.3 0.0 3.5e-13 49.3 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Hom_end PF05204.9 KNE02820.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Homing endonuclease G-alpha PF00503.15 KNE02821.1 - 1.4e-109 366.3 3.0 1.5e-109 366.2 2.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KNE02821.1 - 1.7e-15 56.7 0.6 2.8e-11 42.9 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KNE02821.1 - 2.3e-05 23.6 0.1 0.0015 17.7 0.1 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KNE02821.1 - 7.8e-05 23.1 0.1 0.54 10.7 0.0 2.8 2 1 0 2 2 2 2 Miro-like protein GTP_EFTU PF00009.22 KNE02821.1 - 0.0011 18.4 0.0 0.096 12.1 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_15 PF13175.1 KNE02821.1 - 0.0015 17.7 1.3 0.0024 17.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 KNE02821.1 - 0.0031 17.4 0.0 1.8 8.5 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase Ras PF00071.17 KNE02821.1 - 0.016 14.6 0.1 0.44 9.9 0.0 2.3 2 0 0 2 2 2 0 Ras family Peptidase_M16_C PF05193.16 KNE02822.1 - 8.6e-21 74.4 0.0 2e-20 73.2 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KNE02822.1 - 5.3e-17 61.9 2.6 2.8e-16 59.6 0.6 2.6 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) Ribosomal_S7 PF00177.16 KNE02824.1 - 9.5e-35 119.3 0.6 1.4e-34 118.8 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e CaM-KIIN PF15170.1 KNE02824.1 - 0.073 13.0 0.0 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Calcium/calmodulin-dependent protein kinase II inhibitor PPP4R2 PF09184.6 KNE02825.1 - 5.6e-09 35.9 3.4 2.5e-08 33.8 2.4 1.8 1 1 0 1 1 1 1 PPP4R2 CybS PF05328.7 KNE02826.1 - 9.5e-53 177.3 0.0 1.2e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 CybS Aminotran_1_2 PF00155.16 KNE02829.1 - 2e-70 237.6 0.0 2.2e-70 237.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KNE02829.1 - 7.8e-06 24.4 0.0 1.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KNE02829.1 - 0.00024 19.9 0.0 0.00063 18.5 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KNE02829.1 - 0.00045 19.3 0.0 0.00083 18.4 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KNE02829.1 - 0.019 14.1 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Methyltransf_16 PF10294.4 KNE02830.1 - 1.2e-15 57.3 0.0 2.2e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KNE02830.1 - 2.3e-05 24.1 0.0 4.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.11 KNE02831.1 - 2e-30 105.6 39.4 2e-30 105.6 27.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1674 PF07896.7 KNE02832.1 - 1.4e-16 60.4 2.7 2.7e-16 59.4 1.8 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Methyltransf_28 PF02636.12 KNE02833.1 - 1.3e-74 250.8 0.0 1.7e-74 250.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Metallophos PF00149.23 KNE02834.1 - 1.1e-38 132.6 0.1 1.7e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Crl PF07417.7 KNE02839.1 - 0.038 13.7 0.5 0.043 13.5 0.3 1.2 1 0 0 1 1 1 0 Transcriptional regulator Crl Methyltransf_4 PF02390.12 KNE02839.1 - 0.16 10.9 1.3 0.19 10.7 0.9 1.0 1 0 0 1 1 1 0 Putative methyltransferase Herpes_US9 PF06072.6 KNE02839.1 - 4.5 7.1 6.9 0.68 9.8 1.0 2.0 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 MFS_1 PF07690.11 KNE02841.1 - 2.1e-13 49.7 30.4 3.9e-11 42.2 20.8 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KNE02841.1 - 1.6e-07 29.9 15.4 3.2e-05 22.3 1.4 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KNE02841.1 - 0.00047 18.6 3.7 0.00047 18.6 2.6 4.1 3 1 1 4 4 4 1 MFS/sugar transport protein Abhydrolase_6 PF12697.2 KNE02842.1 - 2.1e-23 83.3 0.0 2.6e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNE02842.1 - 1.9e-07 30.9 0.0 4.1e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNE02842.1 - 9.4e-05 22.0 0.0 0.00079 19.0 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 KNE02842.1 - 0.0002 20.8 0.0 0.00026 20.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.8 KNE02842.1 - 0.049 13.2 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Pantoate_ligase PF02569.10 KNE02843.1 - 6.2e-91 304.0 0.0 7e-91 303.8 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase HA2 PF04408.18 KNE02844.1 - 6.5e-21 74.2 0.0 2.5e-20 72.3 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KNE02844.1 - 1.5e-19 69.9 0.0 5.3e-19 68.1 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KNE02844.1 - 2.8e-13 49.5 0.0 6.2e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KNE02844.1 - 1.1e-07 31.4 0.0 2.9e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KNE02844.1 - 7.8e-06 26.0 0.5 2.5e-05 24.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KNE02844.1 - 0.0015 17.5 0.1 0.003 16.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 KNE02844.1 - 0.0019 17.2 1.1 0.0059 15.6 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Miro PF08477.8 KNE02844.1 - 0.0029 18.1 2.7 0.018 15.5 0.0 3.1 3 0 0 3 3 2 1 Miro-like protein AAA_19 PF13245.1 KNE02844.1 - 0.011 15.4 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 KNE02844.1 - 0.018 14.4 0.1 5.5 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_14 PF13173.1 KNE02844.1 - 0.029 14.2 0.3 0.85 9.5 0.2 2.7 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 KNE02844.1 - 0.031 13.3 1.0 0.099 11.7 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.1 KNE02844.1 - 0.038 13.3 0.0 0.094 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 KNE02844.1 - 0.047 13.4 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain NACHT PF05729.7 KNE02844.1 - 0.096 12.3 1.0 0.59 9.7 0.7 2.3 1 1 0 1 1 1 0 NACHT domain Sigma54_activ_2 PF14532.1 KNE02844.1 - 0.12 12.4 0.8 1.3 9.0 0.0 3.0 4 0 0 4 4 4 0 Sigma-54 interaction domain AAA_29 PF13555.1 KNE02844.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KNE02844.1 - 1.1 9.5 8.9 0.31 11.3 0.1 3.3 3 1 1 4 4 3 0 ABC transporter ResIII PF04851.10 KNE02844.1 - 1.3 8.8 8.9 1.2 8.8 0.0 3.3 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit DUF4651 PF15513.1 KNE02845.1 - 0.0024 17.3 0.0 0.11 11.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4651) Nup54 PF13874.1 KNE02846.1 - 6.9e-42 142.4 3.3 8e-41 139.0 0.2 2.4 2 0 0 2 2 2 2 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 KNE02846.1 - 1.2e-25 89.9 175.7 2.8e-12 46.8 32.5 4.7 1 1 3 4 4 4 4 Nucleoporin FG repeat region CorA PF01544.13 KNE02846.1 - 0.11 11.5 0.9 0.21 10.6 0.6 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Colipase-like PF15083.1 KNE02847.1 - 0.0022 17.9 5.0 0.0034 17.2 3.5 1.3 1 0 0 1 1 1 1 Colipase-like CHCH PF06747.8 KNE02847.1 - 0.4 10.6 11.2 2.2 8.2 3.3 2.5 2 0 0 2 2 2 0 CHCH domain COX6B PF02297.12 KNE02847.1 - 0.86 9.6 10.9 1.4 8.9 3.1 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 KNE02847.1 - 2.4 8.2 9.0 2.4 8.2 2.7 2.6 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COG2 PF06148.6 KNE02849.1 - 4.9e-20 71.7 2.6 7.7e-20 71.1 1.8 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 KNE02849.1 - 0.00017 21.3 5.4 0.00051 19.8 0.2 2.7 2 1 1 3 3 3 1 Vps51/Vps67 Dor1 PF04124.7 KNE02849.1 - 0.0054 15.2 3.7 0.0082 14.6 2.5 1.2 1 0 0 1 1 1 1 Dor1-like family Sec8_exocyst PF04048.9 KNE02849.1 - 0.89 9.1 5.3 0.26 10.8 1.2 1.8 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain