# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- LAGLIDADG_1 PF00961.14 EEQ69151.1 - 3.5e-14 53.1 2.3 3.5e-14 53.1 1.6 3.9 3 1 1 4 4 4 2 LAGLIDADG endonuclease LAGLIDADG_3 PF14528.1 EEQ69151.1 - 7.9e-05 22.8 0.4 0.089 13.0 0.1 3.4 2 1 1 3 3 3 2 LAGLIDADG-like domain Endonuc_subdom PF09062.5 EEQ69151.1 - 0.016 15.9 0.8 0.016 15.9 0.5 3.1 3 1 1 4 4 4 0 PI-PfuI Endonuclease subdomain LAGLIDADG_1 PF00961.14 EEQ69152.1 - 2.6e-32 111.3 16.5 1.1e-17 64.4 3.7 2.6 3 0 0 3 3 3 2 LAGLIDADG endonuclease LAGLIDADG_3 PF14528.1 EEQ69152.1 - 9e-06 25.8 0.6 0.0026 17.9 0.2 3.0 3 0 0 3 3 3 2 LAGLIDADG-like domain LAGLIDADG_1 PF00961.14 EEQ69153.1 - 2.7e-22 79.2 21.9 7.9e-18 64.8 2.3 3.5 3 1 0 3 3 3 2 LAGLIDADG endonuclease LAGLIDADG_3 PF14528.1 EEQ69153.1 - 2.9e-07 30.6 0.8 0.0003 20.9 0.1 2.7 2 1 0 2 2 2 2 LAGLIDADG-like domain Endonuc_subdom PF09062.5 EEQ69153.1 - 0.0057 17.3 8.9 0.05 14.3 0.1 3.7 2 2 1 3 3 3 1 PI-PfuI Endonuclease subdomain LAGLIDADG_1 PF00961.14 EEQ69154.1 - 6.1e-22 78.1 1.9 6.9e-22 77.9 1.3 1.0 1 0 0 1 1 1 1 LAGLIDADG endonuclease LAGLIDADG_1 PF00961.14 EEQ69155.1 - 1.6e-07 31.8 6.6 1.5e-06 28.6 4.6 2.1 1 1 0 1 1 1 1 LAGLIDADG endonuclease LAGLIDADG_3 PF14528.1 EEQ69155.1 - 2.2e-05 24.6 0.8 6.1e-05 23.1 0.6 1.8 1 1 0 1 1 1 1 LAGLIDADG-like domain Hom_end PF05204.9 EEQ69155.1 - 0.0051 16.7 0.2 0.05 13.5 0.0 2.2 1 1 1 2 2 2 2 Homing endonuclease LAGLIDADG_1 PF00961.14 EEQ69156.1 - 1.3e-10 41.7 1.3 1.3e-10 41.7 0.9 1.5 1 1 0 1 1 1 1 LAGLIDADG endonuclease BpuSI_N PF15516.1 EEQ69156.1 - 0.027 14.1 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 BpuSI N-terminal domain LAGLIDADG_1 PF00961.14 EEQ69157.1 - 2.7e-20 72.7 1.0 2.7e-20 72.7 0.7 1.7 2 0 0 2 2 2 1 LAGLIDADG endonuclease Phage_int_SAM_3 PF14659.1 EEQ69157.1 - 0.2 11.9 0.5 0.2 11.9 0.3 2.6 2 1 1 3 3 3 0 Phage integrase, N-terminal SAM-like domain LAGLIDADG_1 PF00961.14 EEQ69158.1 - 9.8e-30 103.1 14.0 3e-20 72.6 2.1 3.2 3 0 0 3 3 3 2 LAGLIDADG endonuclease LAGLIDADG_3 PF14528.1 EEQ69158.1 - 0.0036 17.5 1.1 0.067 13.4 0.0 3.0 2 1 1 3 3 3 1 LAGLIDADG-like domain Herpes_alk_exo PF01771.12 EEQ69158.1 - 0.013 13.9 0.0 0.02 13.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus alkaline exonuclease DUF4264 PF14084.1 EEQ69158.1 - 0.017 14.4 0.3 0.066 12.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4264) Peroxin-22 PF12827.2 EEQ69158.1 - 0.036 13.7 1.2 1.8 8.3 0.2 2.6 1 1 1 2 2 2 0 Peroxisomal biogenesis protein family COX1 PF00115.15 EEQ69159.1 - 2.1e-80 270.5 52.0 1.9e-36 125.6 3.7 3.4 1 1 1 3 3 3 3 Cytochrome C and Quinol oxidase polypeptide I LAGLIDADG_2 PF03161.8 EEQ69160.1 - 2e-29 102.7 0.4 1.3e-28 100.0 0.3 2.0 1 1 0 1 1 1 1 LAGLIDADG DNA endonuclease family LAGLIDADG_3 PF14528.1 EEQ69160.1 - 7.1e-05 22.9 0.7 0.0036 17.4 0.1 3.0 3 0 0 3 3 3 1 LAGLIDADG-like domain Intein_splicing PF14890.1 EEQ69160.1 - 0.00051 19.0 1.4 0.00089 18.2 1.0 1.6 1 1 0 1 1 1 1 Intein splicing domain MutS_IV PF05190.13 EEQ69160.1 - 0.031 14.4 0.3 0.031 14.4 0.2 1.6 2 0 0 2 2 2 0 MutS family domain IV Ribosomal_S3_C PF00189.15 EEQ69161.1 - 0.00011 22.3 1.0 0.00011 22.3 0.7 3.4 3 1 0 3 3 3 1 Ribosomal protein S3, C-terminal domain COX3 PF00510.13 EEQ69162.1 - 1.2e-114 382.1 28.7 1.3e-114 381.9 19.9 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III Oxidored_q3 PF00499.15 EEQ69163.1 - 2.5e-25 88.9 39.7 7.1e-25 87.4 27.5 1.6 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF1443 PF07280.6 EEQ69163.1 - 0.035 13.6 2.7 0.035 13.6 1.9 4.7 5 1 1 6 6 6 0 Protein of unknown function (DUF1443) LAGLIDADG_1 PF00961.14 EEQ69164.1 - 3e-19 69.4 10.1 8.9e-13 48.6 2.8 3.1 2 1 1 3 3 3 2 LAGLIDADG endonuclease Sipho_Gp37 PF14594.1 EEQ69164.1 - 0.0043 16.3 0.2 0.0054 16.0 0.1 1.1 1 0 0 1 1 1 1 Siphovirus ReqiPepy6 Gp37-like protein Spc7 PF08317.6 EEQ69165.1 - 0.004 15.8 6.0 0.0062 15.2 4.1 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Peptidase_C6 PF00851.13 EEQ69165.1 - 0.024 13.3 3.5 0.034 12.7 2.4 1.1 1 0 0 1 1 1 0 Helper component proteinase Pex24p PF06398.6 EEQ69165.1 - 0.033 12.9 4.5 0.11 11.2 0.0 2.7 2 1 0 3 3 3 0 Integral peroxisomal membrane peroxin DUF883 PF05957.8 EEQ69165.1 - 0.038 14.3 0.5 0.088 13.2 0.4 1.6 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF883) DUF3486 PF11985.3 EEQ69165.1 - 0.069 13.2 1.7 0.11 12.5 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) SLAC1 PF03595.12 EEQ69165.1 - 0.075 11.6 5.6 0.026 13.1 0.9 1.9 2 0 0 2 2 2 0 Voltage-dependent anion channel Z1 PF10593.4 EEQ69165.1 - 0.087 12.0 1.2 0.12 11.5 0.8 1.2 1 0 0 1 1 1 0 Z1 domain EAP30 PF04157.11 EEQ69165.1 - 0.19 10.8 4.9 0.26 10.4 3.4 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family MFS_1 PF07690.11 EEQ69165.1 - 0.36 9.5 7.5 0.46 9.1 5.2 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF2203 PF09969.4 EEQ69165.1 - 0.86 9.8 3.1 12 6.1 1.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF443 PF04276.7 EEQ69165.1 - 1.8 7.9 18.0 3.8 6.9 12.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Flu_M2 PF00599.12 EEQ69165.1 - 4.1 7.2 4.9 0.44 10.3 0.1 1.9 2 0 0 2 2 2 0 Influenza Matrix protein (M2) ATP-synt_A PF00119.15 EEQ69166.1 - 1.1e-50 172.0 31.0 1.3e-50 171.8 21.5 1.0 1 0 0 1 1 1 1 ATP synthase A chain Fun_ATP-synt_8 PF05933.8 EEQ69167.1 - 5.4e-19 67.9 11.9 5.9e-19 67.8 8.2 1.0 1 0 0 1 1 1 1 Fungal ATP synthase protein 8 (A6L) ATP-synt_8 PF00895.15 EEQ69167.1 - 9.3 6.5 7.6 14 6.0 5.0 1.6 1 1 0 1 1 1 0 ATP synthase protein 8 Oxidored_q1 PF00361.15 EEQ69168.1 - 1.9e-29 102.7 8.3 1.9e-29 102.7 5.7 2.0 2 0 0 2 2 2 2 NADH-Ubiquinone/plastoquinone (complex I), various chains LAGLIDADG_1 PF00961.14 EEQ69169.1 - 6.4e-18 65.1 10.8 1.8e-10 41.2 2.6 3.8 3 1 1 4 4 4 2 LAGLIDADG endonuclease LAGLIDADG_3 PF14528.1 EEQ69169.1 - 4.5e-07 30.0 15.9 0.00078 19.6 3.0 4.3 3 2 0 3 3 3 2 LAGLIDADG-like domain Hom_end PF05204.9 EEQ69169.1 - 0.0002 21.2 0.2 0.61 10.0 0.0 3.2 2 1 1 3 3 3 2 Homing endonuclease Oxidored_q1 PF00361.15 EEQ69170.1 - 2.3e-77 259.8 33.2 2.3e-77 259.8 23.0 4.1 4 2 0 5 5 5 1 NADH-Ubiquinone/plastoquinone (complex I), various chains Oxidored_q1_N PF00662.15 EEQ69170.1 - 5.1e-22 77.2 8.1 5.1e-22 77.2 5.6 3.7 4 0 0 4 4 4 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Oxidored_q2 PF00420.19 EEQ69171.1 - 8.7e-22 76.5 13.1 9.2e-22 76.4 9.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L LAGLIDADG_2 PF03161.8 EEQ69172.1 - 1.6e-43 148.6 2.0 1.8e-43 148.4 1.4 1.0 1 0 0 1 1 1 1 LAGLIDADG DNA endonuclease family Fip1 PF05182.8 EEQ69172.1 - 0.066 12.5 5.6 0.12 11.6 0.0 2.4 2 0 0 2 2 2 0 Fip1 motif COX2 PF00116.15 EEQ69173.1 - 8.4e-51 170.8 0.1 1.4e-50 170.1 0.1 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain COX2_TM PF02790.10 EEQ69173.1 - 3.6e-32 110.1 5.8 8.3e-32 109.0 4.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain DUF973 PF06157.6 EEQ69173.1 - 0.53 9.2 6.3 0.19 10.6 2.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF973) ATP-synt_C PF00137.16 EEQ69174.1 - 5.7e-18 64.5 16.0 6.4e-18 64.4 11.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit C TMEM213 PF15192.1 EEQ69174.1 - 0.078 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 TMEM213 family MFS_3 PF05977.8 EEQ69174.1 - 3.1 5.7 6.0 3 5.8 4.1 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector NADHdh PF00146.16 EEQ69176.1 - 3.5e-102 341.6 26.0 1.2e-101 339.9 18.0 1.8 1 1 0 1 1 1 1 NADH dehydrogenase Peptidase_M50 PF02163.17 EEQ69176.1 - 0.035 13.0 0.0 0.17 10.8 0.0 2.2 1 1 0 1 1 1 0 Peptidase family M50 Oxidored_q4 PF00507.14 EEQ69177.1 - 7e-24 83.5 12.5 7e-24 83.5 8.7 1.4 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF1469 PF07332.6 EEQ69177.1 - 0.12 12.1 0.1 0.12 12.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Tmemb_18A PF09771.4 EEQ69177.1 - 0.14 12.1 2.8 0.073 13.0 0.5 1.5 1 1 0 1 1 1 0 Transmembrane protein 188 Baculo_11_kDa PF06143.6 EEQ69177.1 - 0.34 10.2 0.1 0.34 10.2 0.1 2.7 3 0 0 3 3 3 0 Baculovirus 11 kDa family Rer1 PF03248.8 EEQ69177.1 - 4.9 6.7 8.0 0.063 12.8 0.6 1.5 2 0 0 2 2 2 0 Rer1 family LAGLIDADG_1 PF00961.14 EEQ69178.1 - 1.8e-09 38.0 0.5 3.3e-09 37.2 0.3 1.5 1 0 0 1 1 1 1 LAGLIDADG endonuclease LAGLIDADG_3 PF14528.1 EEQ69178.1 - 0.12 12.5 0.1 0.17 12.1 0.1 1.4 1 1 0 1 1 1 0 LAGLIDADG-like domain LAGLIDADG_1 PF00961.14 EEQ69179.1 - 8.1e-25 87.3 2.7 1.2e-24 86.8 1.9 1.2 1 0 0 1 1 1 1 LAGLIDADG endonuclease Cytochrom_B_N_2 PF13631.1 EEQ69180.1 - 1e-51 175.0 15.1 1e-51 175.0 10.5 2.6 3 1 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.12 EEQ69180.1 - 5.9e-39 132.4 5.5 5.9e-39 132.4 3.8 3.2 3 1 2 5 5 5 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_N PF00033.14 EEQ69180.1 - 2.2e-16 59.7 16.2 2.2e-16 59.7 11.2 2.5 2 1 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Oxidored_q1 PF00361.15 EEQ69181.1 - 1.5e-52 178.5 41.6 1.5e-52 178.5 28.9 4.8 2 2 1 4 4 4 1 NADH-Ubiquinone/plastoquinone (complex I), various chains NADH5_C PF06455.6 EEQ69182.1 - 4.7e-06 26.1 1.0 4.7e-06 26.1 0.7 1.8 1 1 1 2 2 2 1 NADH dehydrogenase subunit 5 C-terminus IF3_C PF00707.17 EEQ69183.1 - 0.03 14.0 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Translation initiation factor IF-3, C-terminal domain Na_H_Exchanger PF00999.16 EEQ69184.1 - 0.24 9.8 20.0 0.31 9.4 13.8 1.1 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family LSM PF01423.17 EEQ69185.1 - 2.3e-15 55.8 0.8 3.2e-15 55.4 0.6 1.2 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 EEQ69185.1 - 0.036 13.7 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) HTH_25 PF13413.1 EEQ69185.1 - 0.06 12.9 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain SM-ATX PF14438.1 EEQ69185.1 - 0.079 12.8 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain DRMBL PF07522.9 EEQ69186.1 - 1.3e-34 118.5 0.0 2.6e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EEQ69186.1 - 1.4e-10 41.0 0.1 2.9e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain p450 PF00067.17 EEQ69187.1 - 3.3e-75 253.3 0.0 4.4e-75 252.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PHO4 PF01384.15 EEQ69188.1 - 3.8e-27 94.8 20.2 3.6e-26 91.5 12.2 2.7 2 1 0 2 2 2 1 Phosphate transporter family DUF1705 PF08019.7 EEQ69188.1 - 0.024 14.1 3.1 2.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1705) Bacteriocin_IIi PF11758.3 EEQ69188.1 - 0.49 10.0 3.4 0.28 10.8 0.3 2.0 2 0 0 2 2 2 0 Aureocin-like type II bacteriocin SNF PF00209.13 EEQ69189.1 - 3.4e-74 250.2 39.1 3.7e-73 246.7 23.3 2.9 2 1 0 2 2 2 2 Sodium:neurotransmitter symporter family Tom37_C PF11801.3 EEQ69191.1 - 0.055 13.3 0.6 0.06 13.2 0.4 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain Methyltransf_11 PF08241.7 EEQ69192.1 - 1.9e-08 34.6 0.0 1.3e-07 31.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ribul_P_3_epim PF00834.14 EEQ69193.1 - 5.8e-61 205.1 0.0 6.9e-60 201.5 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 EEQ69193.1 - 0.012 15.0 0.2 0.15 11.6 0.0 2.2 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain ThiG PF05690.9 EEQ69193.1 - 0.021 13.8 0.1 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG PcrB PF01884.12 EEQ69193.1 - 0.053 12.7 0.1 0.083 12.1 0.1 1.2 1 0 0 1 1 1 0 PcrB family OMPdecase PF00215.19 EEQ69193.1 - 0.087 12.2 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family SH3BGR PF04908.10 EEQ69194.1 - 3.2e-06 26.9 0.0 7.5e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 EEQ69194.1 - 0.0016 18.4 0.1 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 EEQ69194.1 - 0.074 13.2 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain YABBY PF04690.8 EEQ69194.1 - 2.2 8.4 5.9 3.5 7.8 3.8 1.6 1 1 0 1 1 1 0 YABBY protein CAP PF00188.21 EEQ69195.1 - 0.021 15.2 0.0 0.033 14.6 0.0 1.3 1 0 0 1 1 1 0 Cysteine-rich secretory protein family PSI_PsaH PF03244.9 EEQ69196.1 - 0.097 11.9 0.2 0.23 10.7 0.1 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI zf-BED PF02892.10 EEQ69196.1 - 8 6.3 6.6 8.6 6.2 0.3 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_4 PF13894.1 EEQ69197.1 - 0.00085 19.4 12.2 0.15 12.4 0.7 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger DUF2007 PF09413.5 EEQ69198.1 - 0.0037 17.0 0.0 0.0086 15.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2007) NTP_transf_5 PF14907.1 EEQ69198.1 - 0.0077 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised nucleotidyltransferase Pox_A14 PF05767.7 EEQ69199.1 - 0.061 13.2 0.2 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 MS_channel PF00924.13 EEQ69200.1 - 2.7e-22 79.1 3.3 4.7e-22 78.3 2.3 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EEQ69200.1 - 0.00031 19.8 0.3 0.00072 18.6 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EEQ69200.1 - 0.00094 19.2 0.1 0.0025 17.8 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EEQ69200.1 - 0.00094 18.8 0.0 0.0025 17.5 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 EEQ69200.1 - 0.001 18.3 0.0 0.0028 16.9 0.0 1.8 1 0 0 1 1 1 1 EF hand DUF883 PF05957.8 EEQ69201.1 - 0.0026 18.0 0.2 0.0048 17.2 0.1 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) Tubulin PF00091.20 EEQ69202.1 - 3.3e-65 219.9 0.0 4.4e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EEQ69202.1 - 3.6e-44 149.8 0.0 5.5e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EEQ69202.1 - 0.0005 19.5 0.0 0.00089 18.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Mito_carr PF00153.22 EEQ69203.1 - 2.2e-64 213.1 0.8 3e-21 74.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Spore_YhaL PF14147.1 EEQ69203.1 - 0.035 13.5 0.4 0.54 9.7 0.1 2.3 2 0 0 2 2 2 0 Sporulation protein YhaL TauD PF02668.11 EEQ69204.1 - 1.9e-55 188.3 0.1 3.5e-55 187.4 0.1 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EEQ69204.1 - 0.0049 17.2 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF971) Glutaredoxin PF00462.19 EEQ69205.1 - 8.2e-20 70.5 0.0 1.6e-18 66.4 0.0 2.5 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EEQ69205.1 - 7.5e-14 51.2 0.0 1.6e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EEQ69205.1 - 0.00023 21.2 0.0 0.0042 17.1 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin-like TrbC_Ftype PF09673.5 EEQ69205.1 - 0.0057 16.2 0.0 0.16 11.6 0.0 2.6 2 1 0 2 2 2 1 Type-F conjugative transfer system pilin assembly protein Thioredoxin_2 PF13098.1 EEQ69205.1 - 0.01 16.0 0.0 0.46 10.7 0.0 3.1 2 2 1 3 3 3 0 Thioredoxin-like domain ArsC PF03960.10 EEQ69205.1 - 0.12 12.4 0.0 0.78 9.8 0.0 2.0 2 0 0 2 2 2 0 ArsC family RNase_T PF00929.19 EEQ69206.1 - 1.9e-24 86.8 0.0 2.9e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Myb_DNA-bind_6 PF13921.1 EEQ69206.1 - 0.25 11.4 4.4 29 4.8 0.0 3.9 4 0 0 4 4 4 0 Myb-like DNA-binding domain bZIP_2 PF07716.10 EEQ69207.1 - 0.033 13.9 0.2 3.6 7.4 0.1 2.9 2 0 0 2 2 2 0 Basic region leucine zipper Pkinase PF00069.20 EEQ69208.1 - 3.2e-44 151.0 0.0 6.9e-25 87.6 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ69208.1 - 1.2e-18 67.1 0.0 7.8e-11 41.5 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase FHA PF00498.21 EEQ69208.1 - 8.5e-07 29.0 0.1 6.8e-06 26.1 0.1 2.3 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 EEQ69208.1 - 0.04 12.8 0.0 0.064 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF3716 PF12511.3 EEQ69210.1 - 1.1e-16 60.1 10.0 1.6e-16 59.6 7.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Glyco_transf_34 PF05637.7 EEQ69211.1 - 1.8e-66 224.0 0.2 2.3e-66 223.7 0.1 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family NDUFB10 PF10249.4 EEQ69212.1 - 0.072 13.2 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 BRO1 PF03097.13 EEQ69213.1 - 0.00016 20.6 0.0 0.00036 19.3 0.0 1.5 1 1 0 1 1 1 1 BRO1-like domain Bromo_TP PF07524.8 EEQ69214.1 - 6.6e-10 38.5 0.0 1.2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TAFII55_N PF04658.8 EEQ69215.1 - 1.3e-53 180.8 0.0 2.3e-53 180.0 0.0 1.4 1 0 0 1 1 1 1 TAFII55 protein conserved region F-box PF00646.28 EEQ69216.1 - 0.034 13.8 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 F-box domain Folate_carrier PF01770.13 EEQ69216.1 - 0.11 11.0 0.3 0.14 10.6 0.2 1.1 1 0 0 1 1 1 0 Reduced folate carrier bZIP_C PF12498.3 EEQ69217.1 - 0.32 12.2 3.4 2.4 9.4 2.1 2.3 2 0 0 2 2 2 0 Basic leucine-zipper C terminal Ofd1_CTDD PF10637.4 EEQ69219.1 - 1.3e-99 332.6 0.0 1e-94 316.6 0.1 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EEQ69219.1 - 5.4e-16 58.9 0.0 1.1e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BUD22 PF09073.5 EEQ69219.1 - 2.9 6.8 33.7 4.7 6.1 23.4 1.2 1 0 0 1 1 1 0 BUD22 HLH PF00010.21 EEQ69221.1 - 1.8e-08 33.9 0.5 7.8e-08 31.8 0.3 2.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF972 PF06156.8 EEQ69221.1 - 0.015 15.6 0.3 0.039 14.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4404 PF14357.1 EEQ69221.1 - 0.073 13.4 0.6 0.2 12.0 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) SDF PF00375.13 EEQ69223.1 - 5.5e-74 249.2 37.0 1.2e-45 156.0 10.8 2.0 1 1 1 2 2 2 2 Sodium:dicarboxylate symporter family CAAD PF14159.1 EEQ69223.1 - 0.047 13.3 0.2 0.047 13.3 0.1 3.0 3 1 1 4 4 4 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase UCH PF00443.24 EEQ69224.1 - 9.6e-37 126.5 0.0 6.8e-30 104.0 0.0 2.2 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 EEQ69224.1 - 1.1e-33 116.5 0.0 3.4e-31 108.3 0.0 2.3 1 1 1 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.1 EEQ69224.1 - 1.1e-14 54.5 0.0 1.8e-09 37.4 0.0 3.7 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUF87 PF01935.12 EEQ69224.1 - 0.071 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 MATH PF00917.21 EEQ69224.1 - 0.087 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 MATH domain Pkinase PF00069.20 EEQ69225.1 - 2.1e-06 27.1 0.0 3.1e-05 23.2 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Phosphodiest PF01663.17 EEQ69226.1 - 1e-87 294.8 0.2 1.5e-87 294.2 0.2 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EEQ69226.1 - 5.7e-05 22.4 0.0 0.0044 16.2 0.0 2.2 1 1 1 2 2 2 2 Sulfatase PglZ PF08665.7 EEQ69226.1 - 0.00025 20.7 0.0 0.031 13.9 0.0 2.6 2 0 0 2 2 2 1 PglZ domain DUF229 PF02995.12 EEQ69226.1 - 0.061 11.7 0.0 0.09 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Neurensin PF14927.1 EEQ69226.1 - 0.19 11.0 0.4 0.38 10.1 0.0 1.6 2 0 0 2 2 2 0 Neurensin Response_reg PF00072.19 EEQ69227.1 - 2.3e-06 27.5 0.0 3.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Pyr_redox PF00070.22 EEQ69228.1 - 2.6e-14 53.3 0.2 6e-11 42.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEQ69228.1 - 9.1e-13 48.7 0.1 3e-05 24.1 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEQ69228.1 - 5.1e-09 36.3 0.1 0.002 18.0 0.0 3.1 2 2 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEQ69228.1 - 5.4e-07 28.8 0.0 1.5e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 EEQ69228.1 - 1.7e-05 23.9 0.0 0.00027 19.9 0.0 2.2 1 1 1 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 EEQ69228.1 - 2.4e-05 23.3 0.4 0.0022 16.9 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EEQ69228.1 - 0.001 18.2 0.1 0.069 12.1 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.13 EEQ69228.1 - 0.0083 16.1 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.1 EEQ69228.1 - 0.0086 16.3 0.0 0.19 12.0 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding GIDA PF01134.17 EEQ69228.1 - 0.015 14.1 0.0 0.39 9.5 0.0 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A HI0933_like PF03486.9 EEQ69228.1 - 0.06 11.8 0.1 0.33 9.3 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein 2-Hacid_dh_C PF02826.14 EEQ69228.1 - 0.068 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EEQ69228.1 - 0.086 11.6 0.4 6.8 5.4 0.0 2.8 3 0 0 3 3 3 0 FAD binding domain NAD_binding_8 PF13450.1 EEQ69228.1 - 0.088 12.8 0.3 17 5.5 0.0 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DNA_processg_A PF02481.10 EEQ69228.1 - 0.11 11.4 0.0 0.23 10.3 0.0 1.5 1 0 0 1 1 1 0 DNA recombination-mediator protein A Shikimate_DH PF01488.15 EEQ69228.1 - 0.13 12.3 0.1 0.28 11.2 0.0 1.6 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase Mqo PF06039.10 EEQ69228.1 - 0.19 9.8 0.1 0.3 9.1 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Eno-Rase_NADH_b PF12242.3 EEQ69228.1 - 0.3 10.9 2.8 0.74 9.6 0.3 2.6 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ABC_membrane PF00664.18 EEQ69229.1 - 1.8e-78 263.7 28.8 8e-43 146.8 5.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEQ69229.1 - 2.4e-68 228.6 0.1 1.3e-33 116.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EEQ69229.1 - 2e-17 63.1 1.3 6.6e-06 25.5 0.0 4.3 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEQ69229.1 - 1e-09 38.7 1.7 0.0025 17.8 0.0 4.2 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EEQ69229.1 - 1.4e-09 37.2 0.4 0.00042 19.7 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EEQ69229.1 - 4.1e-08 34.0 0.0 0.014 16.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EEQ69229.1 - 9.6e-08 31.0 0.3 0.0032 16.1 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.1 EEQ69229.1 - 5.6e-07 29.7 0.6 0.15 12.1 0.0 4.4 4 1 0 4 4 3 2 AAA domain AAA_16 PF13191.1 EEQ69229.1 - 1e-06 28.8 5.6 0.0007 19.6 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.1 EEQ69229.1 - 2e-06 27.5 0.5 0.12 11.9 0.0 4.3 4 0 0 4 4 4 2 AAA domain DUF258 PF03193.11 EEQ69229.1 - 2.1e-06 27.0 0.0 0.014 14.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EEQ69229.1 - 7.3e-06 25.5 0.7 0.12 11.8 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_10 PF12846.2 EEQ69229.1 - 2.5e-05 23.8 1.7 0.22 10.9 0.0 3.5 3 1 0 3 3 3 1 AAA-like domain DUF87 PF01935.12 EEQ69229.1 - 4e-05 23.5 0.9 0.0067 16.2 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_33 PF13671.1 EEQ69229.1 - 5.5e-05 23.0 0.1 0.34 10.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.1 EEQ69229.1 - 5.9e-05 22.9 0.1 0.28 11.1 0.0 3.4 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EEQ69229.1 - 6.6e-05 23.2 0.1 0.74 10.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 EEQ69229.1 - 0.00017 20.7 0.0 0.013 14.6 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.1 EEQ69229.1 - 0.00028 21.2 0.0 0.31 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EEQ69229.1 - 0.00073 18.7 0.0 0.67 9.0 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI APS_kinase PF01583.15 EEQ69229.1 - 0.001 18.7 0.1 0.65 9.6 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_5 PF07728.9 EEQ69229.1 - 0.0021 17.7 0.0 2.7 7.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EEQ69229.1 - 0.0023 18.1 0.1 4.3 7.5 0.0 4.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EEQ69229.1 - 0.0099 15.8 0.1 5.4 7.0 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.20 EEQ69229.1 - 0.048 13.1 1.5 1.1 8.7 0.0 2.9 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 EEQ69229.1 - 0.049 13.3 0.1 11 5.7 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EEQ69229.1 - 0.061 13.2 0.0 19 5.1 0.0 3.6 4 0 0 4 4 4 0 AAA domain AAA_15 PF13175.1 EEQ69229.1 - 0.11 11.4 0.0 0.29 10.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.15 EEQ69229.1 - 0.19 10.3 0.0 3.3 6.2 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit Condensation PF00668.15 EEQ69230.1 - 1e-60 205.1 0.0 2.5e-37 128.3 0.0 2.5 2 0 0 2 2 2 2 Condensation domain AMP-binding PF00501.23 EEQ69230.1 - 3.8e-36 124.3 0.1 6.9e-31 107.0 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.20 EEQ69230.1 - 3.4e-27 94.4 2.4 7.7e-14 51.7 0.1 3.3 3 0 0 3 3 3 2 Phosphopantetheine attachment site RTA1 PF04479.8 EEQ69231.1 - 2.1e-17 63.3 7.5 2.6e-17 63.0 5.2 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF2755 PF10954.3 EEQ69231.1 - 0.59 9.8 7.0 4.6 7.0 0.0 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2755) MFS_1 PF07690.11 EEQ69232.1 - 2.7e-21 75.7 57.0 2.8e-20 72.3 39.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ69232.1 - 1.6e-09 36.5 24.7 2e-09 36.2 17.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Acetyltransf_1 PF00583.19 EEQ69233.1 - 3.1e-11 43.1 0.0 5.2e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ69233.1 - 1.9e-07 31.1 0.0 6.2e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEQ69233.1 - 9.8e-05 22.4 0.0 0.00023 21.2 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEQ69233.1 - 0.0047 16.7 0.0 0.028 14.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ69233.1 - 0.029 14.1 0.0 0.18 11.6 0.0 2.1 1 1 0 1 1 1 0 FR47-like protein MaoC_dehydratas PF01575.14 EEQ69234.1 - 8.2e-18 63.9 0.0 1.9e-17 62.7 0.0 1.6 1 1 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EEQ69234.1 - 2.9e-06 27.0 0.0 7.4e-05 22.5 0.0 2.4 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase 4HBT PF03061.17 EEQ69234.1 - 0.0062 16.6 0.0 0.021 14.9 0.0 1.9 2 0 0 2 2 2 1 Thioesterase superfamily K_oxygenase PF13434.1 EEQ69235.1 - 1e-110 369.8 0.0 1.2e-110 369.6 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EEQ69235.1 - 2e-11 43.9 0.1 5.5e-07 29.4 0.0 3.1 2 1 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EEQ69235.1 - 1.6e-10 41.3 0.0 6.2e-10 39.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEQ69235.1 - 7.7e-08 32.4 0.0 5e-07 29.8 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EEQ69235.1 - 0.00023 20.2 0.0 0.073 11.9 0.0 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox PF00070.22 EEQ69235.1 - 0.00098 19.4 0.0 0.087 13.2 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEQ69235.1 - 0.01 14.7 0.0 0.76 8.5 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.1 EEQ69235.1 - 0.089 12.8 0.0 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain AMP-binding PF00501.23 EEQ69236.1 - 3.6e-98 328.6 0.0 4.5e-98 328.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ69236.1 - 5.7e-16 59.2 0.0 1.7e-15 57.6 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Acetyltransf_8 PF13523.1 EEQ69237.1 - 4.9e-44 149.8 1.9 7.4e-44 149.2 1.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEQ69237.1 - 0.0051 16.9 0.2 0.0089 16.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CBFB_NFYA PF02045.10 EEQ69239.1 - 4.5e-30 103.9 3.6 4.5e-30 103.9 2.5 2.6 2 1 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.7 EEQ69239.1 - 0.15 10.9 0.1 0.15 10.9 0.0 2.2 2 0 0 2 2 2 0 Hus1-like protein Kinesin PF00225.18 EEQ69241.1 - 1.8e-107 358.9 0.0 2.9e-107 358.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 EEQ69241.1 - 8.1e-44 148.6 0.0 1.9e-43 147.4 0.0 1.7 1 0 0 1 1 1 1 Kinesin protein KIF1B PF12423.3 EEQ69241.1 - 7.5e-07 29.0 0.3 2.4e-06 27.4 0.2 2.0 1 0 0 1 1 1 1 Kinesin protein 1B PH PF00169.24 EEQ69241.1 - 1.8e-06 28.1 0.0 4.8e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 PH domain Cu-oxidase_3 PF07732.10 EEQ69242.1 - 1.2e-10 41.1 0.4 2e-07 30.7 0.1 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EEQ69242.1 - 8.2e-06 25.3 0.2 0.04 13.4 0.0 3.0 3 0 0 3 3 3 2 Multicopper oxidase Glyco_transf_90 PF05686.7 EEQ69243.1 - 2.6e-27 95.5 0.6 4e-27 94.9 0.4 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 EEQ69243.1 - 0.0047 17.1 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF2367 PF10164.4 EEQ69244.1 - 0.13 12.1 0.2 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Glyco_hydro_43 PF04616.9 EEQ69245.1 - 2.5e-31 108.8 0.0 3.3e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF3546 PF12066.3 EEQ69246.1 - 3.3e-27 94.6 2.7 1e-26 93.0 1.8 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 EEQ69246.1 - 1.4e-24 85.4 0.1 3.1e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 EEQ69246.1 - 2.2e-09 37.8 0.2 4.6e-09 36.7 0.2 1.6 1 0 0 1 1 1 1 Arsenite-resistance protein 2 NTP_transf_2 PF01909.18 EEQ69246.1 - 0.64 10.3 3.1 0.38 11.1 0.4 1.9 2 0 0 2 2 2 0 Nucleotidyltransferase domain Amidase PF01425.16 EEQ69248.1 - 2.3e-84 283.8 0.0 3.1e-84 283.3 0.0 1.1 1 0 0 1 1 1 1 Amidase bZIP_1 PF00170.16 EEQ69249.1 - 0.00029 20.7 4.3 0.00066 19.5 3.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEQ69249.1 - 3.1 7.6 10.6 0.39 10.5 3.4 2.2 2 0 0 2 2 2 0 Basic region leucine zipper eIF-3_zeta PF05091.7 EEQ69250.1 - 8.9e-199 661.3 0.0 1e-198 661.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pkinase PF00069.20 EEQ69251.1 - 1.9e-59 200.9 0.0 2.1e-38 131.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ69251.1 - 5.8e-29 100.9 0.0 1.2e-20 73.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EEQ69251.1 - 5.1e-11 42.5 0.0 1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EEQ69251.1 - 2.6e-06 26.6 0.2 3e-05 23.1 0.0 2.4 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EEQ69251.1 - 2e-05 24.4 0.0 0.006 16.3 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EEQ69251.1 - 0.0065 15.5 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS PF00989.19 EEQ69251.1 - 0.043 13.6 0.1 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 PAS fold RIO1 PF01163.17 EEQ69251.1 - 0.063 12.6 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 EEQ69251.1 - 0.13 11.1 0.1 0.26 10.0 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 PAS_9 PF13426.1 EEQ69251.1 - 0.29 11.5 0.0 0.78 10.1 0.0 1.7 1 0 0 1 1 1 0 PAS domain 3Beta_HSD PF01073.14 EEQ69252.1 - 2.7e-45 154.2 0.0 3.1e-39 134.3 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EEQ69252.1 - 1.9e-25 89.7 0.0 2.5e-24 86.0 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EEQ69252.1 - 7.4e-14 51.2 0.0 1.8e-09 36.8 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EEQ69252.1 - 1.2e-07 30.8 0.0 8.1e-06 24.9 0.0 2.3 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EEQ69252.1 - 4.6e-05 23.4 0.0 0.0037 17.2 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EEQ69252.1 - 0.00011 21.2 0.0 0.14 11.0 0.0 2.4 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein adh_short PF00106.20 EEQ69252.1 - 0.0056 16.6 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EEQ69252.1 - 0.038 13.6 0.1 0.18 11.4 0.0 2.1 1 1 0 1 1 1 0 KR domain UQ_con PF00179.21 EEQ69253.1 - 1.7e-43 147.4 0.0 2.5e-31 107.9 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme UEV PF05743.8 EEQ69253.1 - 1.8e-05 24.4 0.0 0.002 17.8 0.0 2.4 2 0 0 2 2 2 1 UEV domain Prok-E2_B PF14461.1 EEQ69253.1 - 7.8e-05 22.4 0.1 0.036 13.8 0.1 2.9 2 1 0 2 2 2 2 Prokaryotic E2 family B RWD PF05773.17 EEQ69253.1 - 0.001 18.9 0.0 0.069 13.0 0.0 2.7 2 1 0 2 2 2 1 RWD domain bZIP_1 PF00170.16 EEQ69254.1 - 0.00036 20.4 4.8 0.0012 18.7 3.3 1.9 1 0 0 1 1 1 1 bZIP transcription factor OmpH PF03938.9 EEQ69254.1 - 2.1 8.2 16.3 2.1 8.2 6.9 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) AA_permease_2 PF13520.1 EEQ69256.1 - 6.6e-57 192.9 21.5 6.7e-57 192.9 14.4 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ69256.1 - 4.5e-11 41.7 22.8 4.5e-11 41.7 15.8 3.0 2 1 0 2 2 2 1 Amino acid permease Methyltransf_31 PF13847.1 EEQ69257.1 - 3.7e-28 98.0 0.0 5.6e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ69257.1 - 1.1e-16 61.0 0.0 2.4e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ69257.1 - 5.3e-12 45.3 0.0 8.1e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EEQ69257.1 - 5.8e-12 45.6 0.0 1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ69257.1 - 1.8e-11 44.6 0.0 4.4e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ69257.1 - 2.8e-11 43.6 0.0 8.1e-11 42.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ69257.1 - 7.3e-10 38.9 0.1 1.3e-09 38.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EEQ69257.1 - 6e-09 35.4 0.5 1e-08 34.7 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 EEQ69257.1 - 8.3e-09 35.8 0.0 1.6e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EEQ69257.1 - 8.8e-08 31.9 0.0 1.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EEQ69257.1 - 1.7e-05 24.5 0.0 3.5e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ69257.1 - 2e-05 24.0 0.1 3.5e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 EEQ69257.1 - 0.00026 20.6 0.2 0.00045 19.8 0.1 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 CMAS PF02353.15 EEQ69257.1 - 0.00097 18.2 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NNMT_PNMT_TEMT PF01234.12 EEQ69257.1 - 0.0022 16.9 0.1 0.52 9.2 0.0 2.2 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family bZIP_1 PF00170.16 EEQ69258.1 - 0.016 15.1 10.3 0.026 14.4 6.7 1.6 1 1 1 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 EEQ69258.1 - 0.017 14.9 11.8 0.017 14.9 8.2 1.6 1 1 0 1 1 1 0 Basic region leucine zipper Sybindin PF04099.7 EEQ69259.1 - 3.4e-31 107.8 0.0 8e-31 106.6 0.0 1.5 2 0 0 2 2 2 1 Sybindin-like family Sedlin_N PF04628.8 EEQ69259.1 - 3.5e-09 36.6 0.1 6.5e-09 35.7 0.0 1.5 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region DUF566 PF04484.7 EEQ69259.1 - 2.5 7.5 5.1 2.9 7.3 3.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) VWA_2 PF13519.1 EEQ69260.1 - 7.4e-12 45.7 0.4 8.6e-12 45.4 0.3 1.2 1 1 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EEQ69260.1 - 4.1e-06 26.5 0.0 5.9e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 EEQ69260.1 - 0.00019 21.1 0.1 0.00033 20.4 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 EEQ69260.1 - 0.0039 16.6 0.9 0.013 15.0 0.6 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif RSS_P20 PF11757.3 EEQ69260.1 - 0.0094 16.0 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 1 Suppressor of RNA silencing P21-like Cwf_Cwc_15 PF04889.7 EEQ69260.1 - 0.017 14.8 3.1 0.029 14.1 2.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Radial_spoke_3 PF06098.6 EEQ69260.1 - 0.1 11.5 3.2 0.17 10.8 2.2 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 zf-GRF PF06839.7 EEQ69261.1 - 0.02 14.8 0.1 0.043 13.7 0.1 1.6 1 0 0 1 1 1 0 GRF zinc finger Met_10 PF02475.11 EEQ69262.1 - 8.7e-64 214.7 0.0 1.3e-63 214.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.10 EEQ69262.1 - 0.098 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase RNA_pol_Rpb4 PF03874.11 EEQ69263.1 - 8.1e-23 80.6 3.1 1e-22 80.3 2.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF4102 PF13356.1 EEQ69263.1 - 0.085 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4102) MT-A70 PF05063.9 EEQ69263.1 - 0.1 12.1 0.6 0.92 9.0 0.0 2.1 1 1 1 2 2 2 0 MT-A70 DUF2312 PF10073.4 EEQ69263.1 - 0.19 11.0 2.2 0.23 10.8 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) LIM PF00412.17 EEQ69264.1 - 9.5e-28 96.0 33.9 1.1e-12 47.8 4.2 4.7 5 0 0 5 5 5 4 LIM domain RhoGAP PF00620.22 EEQ69264.1 - 6.9e-23 80.9 0.2 5.9e-15 55.1 0.0 2.4 1 1 1 2 2 2 2 RhoGAP domain Nbl1_Borealin_N PF10444.4 EEQ69265.1 - 4.9e-22 77.0 2.8 7.8e-22 76.4 2.0 1.3 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal DUF3818 PF12825.2 EEQ69266.1 - 2.7e-138 460.3 3.2 3.8e-138 459.8 2.2 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EEQ69266.1 - 1e-44 151.4 0.3 2.4e-44 150.2 0.2 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EEQ69266.1 - 4.4e-12 45.7 0.1 8.2e-11 41.6 0.0 2.9 2 1 0 2 2 2 1 PX domain zf-C2H2 PF00096.21 EEQ69267.1 - 0.00021 21.4 3.9 0.00021 21.4 2.7 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ69267.1 - 0.087 13.1 16.5 0.044 14.1 1.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Peptidase_S9 PF00326.16 EEQ69268.1 - 1.2e-19 70.3 0.0 9.3e-11 41.3 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEQ69268.1 - 0.002 17.8 0.0 0.0037 17.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EEQ69268.1 - 0.12 11.9 0.2 5 6.6 0.0 2.5 1 1 2 3 3 3 0 alpha/beta hydrolase fold AAA PF00004.24 EEQ69269.1 - 7.9e-50 168.4 0.0 4.6e-43 146.5 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEQ69269.1 - 5.2e-08 33.7 0.0 0.0014 19.4 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.1 EEQ69269.1 - 5.4e-05 22.6 0.0 0.00051 19.5 0.0 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEQ69269.1 - 9.2e-05 21.5 0.1 0.00049 19.2 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EEQ69269.1 - 0.00021 21.4 0.0 0.0068 16.5 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EEQ69269.1 - 0.00026 20.9 0.0 0.29 11.0 0.0 3.6 3 0 0 3 3 3 1 AAA domain Parvo_NS1 PF01057.12 EEQ69269.1 - 0.00037 19.4 0.0 0.00082 18.3 0.0 1.5 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.17 EEQ69269.1 - 0.00065 19.8 0.0 0.014 15.5 0.0 3.1 3 0 0 3 3 2 1 RNA helicase IstB_IS21 PF01695.12 EEQ69269.1 - 0.0012 18.2 0.0 0.003 17.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 EEQ69269.1 - 0.0018 18.2 5.3 0.025 14.5 0.0 4.6 4 1 1 5 5 5 1 AAA ATPase domain AAA_2 PF07724.9 EEQ69269.1 - 0.0026 17.7 0.0 0.0071 16.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EEQ69269.1 - 0.0029 17.3 0.1 0.029 14.1 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 EEQ69269.1 - 0.0041 17.4 0.0 0.1 12.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EEQ69269.1 - 0.0048 15.6 0.0 0.0095 14.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 EEQ69269.1 - 0.0072 16.0 0.0 0.079 12.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EEQ69269.1 - 0.0079 16.1 0.0 0.31 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EEQ69269.1 - 0.016 14.8 0.0 2.1 7.9 0.0 3.1 3 0 0 3 3 2 0 NACHT domain KaiC PF06745.8 EEQ69269.1 - 0.016 14.3 0.1 0.071 12.2 0.0 2.1 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.7 EEQ69269.1 - 0.017 14.2 0.0 0.6 9.1 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin Mg_chelatase PF01078.16 EEQ69269.1 - 0.018 14.2 0.1 0.043 12.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EEQ69269.1 - 0.025 14.0 0.1 2 7.8 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.11 EEQ69269.1 - 0.04 13.1 0.0 0.088 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein RNA_binding PF01877.12 EEQ69269.1 - 0.05 13.6 0.4 0.13 12.2 0.3 1.7 1 0 0 1 1 1 0 RNA binding AAA_28 PF13521.1 EEQ69269.1 - 0.052 13.5 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain UPF0079 PF02367.12 EEQ69269.1 - 0.08 12.5 0.2 1.3 8.6 0.0 2.9 4 0 0 4 4 4 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EEQ69269.1 - 0.098 12.2 0.1 0.24 10.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EEQ69269.1 - 0.16 11.4 1.0 7.5 6.1 0.1 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain PPV_E1_C PF00519.12 EEQ69269.1 - 0.27 9.8 0.0 0.42 9.1 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase DUF4243 PF14027.1 EEQ69272.1 - 5.4e-83 279.1 0.2 6.5e-83 278.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) HECT_2 PF09814.4 EEQ69273.1 - 4.6e-63 213.0 0.0 1.8e-30 105.8 0.0 2.3 2 0 0 2 2 2 2 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.9 EEQ69273.1 - 0.0028 17.6 0.1 0.22 11.5 0.0 2.4 2 0 0 2 2 2 2 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF4475 PF14753.1 EEQ69274.1 - 6.4 6.2 6.9 0.93 8.9 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4475) PI-PLC-X PF00388.14 EEQ69276.1 - 1.1e-63 212.9 0.0 1.7e-63 212.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EEQ69276.1 - 1.6e-38 131.2 0.1 2.8e-38 130.5 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain DPPIV_N PF00930.16 EEQ69277.1 - 8.7e-103 343.5 0.0 1.2e-102 343.1 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EEQ69277.1 - 1e-55 188.2 1.3 8.7e-55 185.2 1.5 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEQ69277.1 - 5.4e-10 39.2 0.1 9.7e-10 38.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EEQ69277.1 - 1.6e-06 27.7 1.8 7.6e-06 25.5 1.0 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EEQ69277.1 - 4.1e-06 26.8 0.1 8e-05 22.6 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EEQ69277.1 - 0.0081 15.6 0.1 2.3 7.5 0.1 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.8 EEQ69277.1 - 0.0097 14.2 0.0 1.4 7.1 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II PBP1_TM PF14812.1 EEQ69277.1 - 0.013 15.8 0.1 0.033 14.4 0.1 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAD_binding_2 PF00890.19 EEQ69278.1 - 5.1e-127 424.1 3.8 6.9e-127 423.7 2.6 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EEQ69278.1 - 1.1e-47 161.1 0.5 1.6e-47 160.5 0.3 1.2 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EEQ69278.1 - 1.3e-07 31.7 0.0 0.0016 18.3 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEQ69278.1 - 8.3e-06 25.0 0.2 0.013 14.5 0.0 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 EEQ69278.1 - 1.3e-05 24.2 2.0 0.028 13.2 1.6 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EEQ69278.1 - 4.8e-05 22.4 0.2 0.0014 17.5 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EEQ69278.1 - 0.0038 16.3 0.2 0.0094 15.0 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain DUF600 PF04634.7 EEQ69278.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF600 HI0933_like PF03486.9 EEQ69278.1 - 0.12 10.7 1.5 0.46 8.8 0.3 2.4 3 0 0 3 3 3 0 HI0933-like protein AAA PF00004.24 EEQ69279.1 - 4.8e-41 140.0 0.0 8.2e-41 139.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEQ69279.1 - 4.9e-06 26.7 0.0 0.00059 19.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEQ69279.1 - 4.1e-05 23.3 0.1 0.00026 20.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EEQ69279.1 - 0.00017 21.5 0.0 0.00059 19.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EEQ69279.1 - 0.00023 21.2 0.0 0.00093 19.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 EEQ69279.1 - 0.0018 17.2 0.0 0.0032 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EEQ69279.1 - 0.0032 18.2 0.1 0.013 16.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEQ69279.1 - 0.0089 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EEQ69279.1 - 0.0095 15.6 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EEQ69279.1 - 0.017 15.0 0.1 0.045 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EEQ69279.1 - 0.024 14.5 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EEQ69279.1 - 0.035 13.9 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EEQ69279.1 - 0.047 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 EEQ69279.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EEQ69279.1 - 0.07 12.7 0.0 0.62 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EEQ69279.1 - 0.071 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 EEQ69279.1 - 0.077 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 EEQ69279.1 - 0.092 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EEQ69279.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 EEQ69279.1 - 0.11 12.1 0.2 9.8 5.7 0.0 2.5 2 1 1 3 3 3 0 Archaeal ATPase Cpn60_TCP1 PF00118.19 EEQ69280.1 - 1.7e-134 449.1 10.8 2.1e-134 448.8 7.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 EEQ69280.1 - 0.05 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X Octopine_DH PF02317.12 EEQ69281.1 - 0.14 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Ribosomal_L37 PF08561.5 EEQ69282.1 - 1.5e-26 91.7 3.2 2e-25 88.1 2.2 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 Alg6_Alg8 PF03155.10 EEQ69283.1 - 1.3e-130 436.4 24.6 1.5e-83 281.2 8.0 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family DUF2029 PF09594.5 EEQ69283.1 - 9.7e-05 21.9 10.1 9.7e-05 21.9 7.0 3.8 3 1 1 4 4 4 1 Protein of unknown function (DUF2029) Ank PF00023.25 EEQ69284.1 - 2.9e-35 118.3 1.9 6.9e-06 25.6 0.0 6.5 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.2 EEQ69284.1 - 5.6e-33 113.1 0.1 3.9e-16 59.1 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EEQ69284.1 - 3.5e-28 94.8 0.1 0.00046 20.1 0.0 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 EEQ69284.1 - 4.5e-24 83.9 1.9 3.3e-08 33.5 0.1 5.7 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEQ69284.1 - 2.8e-23 81.8 1.5 2.4e-07 31.0 0.1 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) RRM_1 PF00076.17 EEQ69285.1 - 9.9e-41 137.2 0.0 4.2e-19 67.9 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ69285.1 - 1.8e-36 123.9 0.0 7.5e-18 64.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ69285.1 - 5.2e-22 77.4 0.0 3.4e-10 39.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_pp38 PF04846.8 EEQ69286.1 - 0.011 14.9 0.4 0.063 12.5 0.2 2.1 2 0 0 2 2 2 0 Herpesvirus pp38 phosphoprotein SOG2 PF10428.4 EEQ69286.1 - 1 7.9 21.9 0.14 10.7 0.7 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein COX17 PF05051.8 EEQ69287.1 - 5.4e-21 74.3 5.1 6.5e-21 74.1 3.5 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 EEQ69287.1 - 0.0034 17.1 1.9 0.022 14.4 0.0 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like LRR_6 PF13516.1 EEQ69288.1 - 3.8e-09 35.6 0.1 9.5 6.6 0.0 6.2 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.2 EEQ69288.1 - 0.00046 19.7 4.7 2.9 7.6 0.0 5.7 4 2 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EEQ69288.1 - 0.0042 16.9 0.1 60 4.2 0.0 5.4 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_7 PF13504.1 EEQ69288.1 - 0.027 14.5 0.1 46 4.8 0.0 4.8 4 0 0 4 4 4 0 Leucine rich repeat PRTP PF01366.13 EEQ69288.1 - 2.2 6.1 4.0 0.9 7.4 1.0 1.5 2 0 0 2 2 2 0 Herpesvirus processing and transport protein Atg14 PF10186.4 EEQ69288.1 - 3.9 6.3 5.9 0.38 9.6 0.8 1.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Prothymosin PF03247.9 EEQ69288.1 - 6.6 6.9 36.0 2.1 8.5 14.4 2.5 2 0 0 2 2 2 0 Prothymosin/parathymosin family IncA PF04156.9 EEQ69288.1 - 9.8 5.7 17.8 0.28 10.7 3.1 2.4 2 0 0 2 2 2 0 IncA protein MBOAT_2 PF13813.1 EEQ69289.1 - 4.4e-16 58.7 0.3 1.6e-15 56.9 0.2 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF4191 PF13829.1 EEQ69289.1 - 0.023 13.8 0.1 0.023 13.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF3815 PF12821.2 EEQ69289.1 - 0.035 14.0 0.6 0.035 14.0 0.4 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3815) VanZ PF04892.7 EEQ69289.1 - 0.15 12.0 2.5 0.58 10.0 0.0 2.9 3 0 0 3 3 3 0 VanZ like family Sec10 PF07393.6 EEQ69292.1 - 3.4e-234 779.2 0.0 4e-234 779.0 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF1548 PF07579.6 EEQ69292.1 - 0.26 11.4 1.5 1.9 8.5 0.1 2.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1548) DUF690 PF05108.8 EEQ69293.1 - 0.034 12.5 0.2 0.049 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF690) Prenyltransf PF01255.14 EEQ69293.1 - 0.13 11.3 0.0 1.5 7.9 0.0 2.4 2 1 0 2 2 2 0 Putative undecaprenyl diphosphate synthase Fungal_trans PF04082.13 EEQ69295.1 - 2.7e-24 85.4 0.0 4.8e-24 84.6 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ69295.1 - 1.6e-08 34.3 12.9 3.2e-08 33.3 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIS_M PF07500.9 EEQ69296.1 - 6.5e-26 90.6 1.8 8.3e-26 90.3 0.5 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EEQ69296.1 - 2.7e-18 65.3 5.9 5.4e-18 64.3 4.1 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EEQ69296.1 - 3.4e-15 55.2 0.4 6.9e-15 54.2 0.3 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.3 EEQ69296.1 - 0.0071 15.7 1.8 0.023 14.0 1.2 1.9 1 1 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain MPP6 PF10175.4 EEQ69296.1 - 0.024 14.9 0.7 0.051 13.9 0.5 1.6 1 0 0 1 1 1 0 M-phase phosphoprotein 6 7tm_7 PF08395.7 EEQ69297.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor HsbA PF12296.3 EEQ69298.1 - 1.4e-30 105.6 0.2 2e-30 105.1 0.1 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Anemone_cytotox PF06369.7 EEQ69298.1 - 0.054 12.9 0.0 0.076 12.4 0.0 1.1 1 0 0 1 1 1 0 Sea anemone cytotoxic protein SpoIIIAH PF12685.2 EEQ69302.1 - 0.061 12.8 8.2 0.084 12.3 5.7 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein SNAPc19 PF15497.1 EEQ69302.1 - 0.088 13.0 3.2 0.1 12.8 0.2 2.1 1 1 1 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Dendrin PF15498.1 EEQ69302.1 - 0.56 8.6 4.4 0.72 8.2 3.1 1.1 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin Kdo PF06293.9 EEQ69303.1 - 0.054 12.5 0.0 0.081 11.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BNR PF02012.15 EEQ69305.1 - 3.6e-12 44.1 23.0 0.44 10.5 0.1 11.3 11 0 0 11 11 11 6 BNR/Asp-box repeat CHB_HEX_C_1 PF13290.1 EEQ69305.1 - 0.004 16.8 1.5 1.9 8.3 0.0 4.1 4 0 0 4 4 4 1 Chitobiase/beta-hexosaminidase C-terminal domain SGL PF08450.7 EEQ69306.1 - 1.8e-56 191.2 0.1 2.2e-56 191.0 0.1 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EEQ69306.1 - 0.01 15.7 0.0 0.22 11.5 0.0 2.7 2 0 0 2 2 2 0 NHL repeat Arylesterase PF01731.15 EEQ69306.1 - 0.025 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Arylesterase DUF839 PF05787.8 EEQ69306.1 - 0.075 11.9 0.2 1.3 7.9 0.1 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF839) Reg_prop PF07494.6 EEQ69306.1 - 0.11 12.5 4.0 0.78 9.9 0.1 3.7 4 0 0 4 4 4 0 Two component regulator propeller PD40 PF07676.7 EEQ69306.1 - 0.16 11.7 2.2 5.4 6.8 0.0 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat dCMP_cyt_deam_1 PF00383.17 EEQ69307.1 - 1.3e-15 56.9 1.3 1.5e-15 56.7 0.9 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EEQ69307.1 - 3.2e-10 40.0 0.2 4.3e-10 39.6 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Glyco_hydro_7 PF00840.15 EEQ69307.1 - 0.0011 17.3 0.2 0.002 16.6 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 7 LmjF365940-deam PF14421.1 EEQ69307.1 - 0.0034 16.7 2.2 0.048 13.0 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Ank_2 PF12796.2 EEQ69308.1 - 1.6e-12 47.5 3.7 3.3e-08 33.7 0.2 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEQ69308.1 - 2.7e-09 36.9 5.4 0.001 19.2 0.1 4.4 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.25 EEQ69308.1 - 1.1e-08 34.4 0.7 0.0063 16.2 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EEQ69308.1 - 6.6e-06 26.4 1.0 0.083 13.4 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ69308.1 - 0.01 16.0 1.3 72 4.0 0.0 4.7 4 1 0 4 4 4 0 Ankyrin repeat Mito_carr PF00153.22 EEQ69310.1 - 9.9e-63 207.8 2.9 8e-22 76.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Cgr1 PF03879.9 EEQ69311.1 - 1.6e-40 137.6 29.8 1.9e-40 137.4 20.6 1.0 1 0 0 1 1 1 1 Cgr1 family PRP1_N PF06424.7 EEQ69311.1 - 0.23 11.7 10.8 0.33 11.2 7.5 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Birna_RdRp PF04197.7 EEQ69311.1 - 0.64 7.9 6.1 0.69 7.8 4.2 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) Asp-B-Hydro_N PF05279.6 EEQ69311.1 - 0.99 9.1 8.5 1.1 9.0 5.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region 3HCDH_N PF02737.13 EEQ69311.1 - 1.2 8.8 4.4 1.3 8.6 3.1 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ndufs5 PF10200.4 EEQ69311.1 - 2.7 8.0 11.2 0.51 10.3 4.1 2.0 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Reo_sigmaC PF04582.7 EEQ69312.1 - 0.0036 16.5 0.9 0.0054 15.9 0.6 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein PAT1 PF09770.4 EEQ69312.1 - 3.3 5.8 22.7 4.3 5.4 15.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SUI1 PF01253.17 EEQ69313.1 - 4.5e-23 80.8 1.3 7.5e-23 80.1 0.3 1.8 1 1 1 2 2 2 1 Translation initiation factor SUI1 Jnk-SapK_ap_N PF09744.4 EEQ69313.1 - 0.1 12.6 1.3 0.16 11.9 0.9 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 TnpV PF14198.1 EEQ69313.1 - 0.12 12.3 0.2 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Transposon-encoded protein TnpV DUF1752 PF08550.5 EEQ69316.1 - 4.7e-10 38.8 3.3 1.1e-09 37.7 2.3 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF1325 PF07039.6 EEQ69316.1 - 0.0027 17.3 0.1 0.0055 16.3 0.1 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain ELMO_CED12 PF04727.8 EEQ69317.1 - 6.6e-50 168.9 0.3 1.4e-49 167.9 0.2 1.6 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 EEQ69317.1 - 2.8e-06 27.1 0.4 4.2e-05 23.3 0.3 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) Rad17 PF03215.10 EEQ69318.1 - 9e-37 126.9 0.0 2.2e-36 125.6 0.0 1.5 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EEQ69318.1 - 0.0011 19.7 0.0 0.0034 18.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEQ69318.1 - 0.079 13.2 0.6 0.23 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain UAA PF08449.6 EEQ69319.1 - 2.4e-66 223.7 16.0 3.4e-65 219.9 11.1 2.0 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 EEQ69319.1 - 4.9e-05 23.0 11.5 4.9e-05 23.0 8.0 2.7 2 2 0 2 2 2 1 Triose-phosphate Transporter family ATPase_gene1 PF09527.5 EEQ69319.1 - 0.037 13.8 0.3 0.037 13.8 0.2 3.6 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit (ATPase_gene1) EmrE PF13536.1 EEQ69319.1 - 0.35 11.0 25.2 0.32 11.2 2.9 3.3 3 1 0 3 3 3 0 Multidrug resistance efflux transporter GMC_oxred_C PF05199.8 EEQ69320.1 - 7e-17 62.0 0.0 1e-16 61.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EEQ69320.1 - 0.0033 16.6 0.0 0.0099 15.0 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase Dynamin_M PF01031.15 EEQ69321.1 - 1.5e-113 378.4 0.0 2.8e-113 377.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EEQ69321.1 - 4.3e-56 189.3 1.2 2.5e-55 186.8 0.0 2.5 3 0 0 3 3 3 1 Dynamin family GED PF02212.13 EEQ69321.1 - 5.3e-31 106.3 0.4 1.2e-30 105.1 0.3 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EEQ69321.1 - 0.00072 19.5 0.2 0.0048 16.8 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEQ69321.1 - 0.014 15.9 0.0 0.038 14.4 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein RNA_helicase PF00910.17 EEQ69321.1 - 0.13 12.4 0.0 0.71 10.0 0.0 2.2 1 1 0 1 1 1 0 RNA helicase zf-CCHC_4 PF14392.1 EEQ69321.1 - 0.13 11.9 0.1 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle PBP PF01161.15 EEQ69322.1 - 1.4e-26 93.0 0.9 1.9e-26 92.6 0.6 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein SH3_9 PF14604.1 EEQ69323.1 - 4.6e-29 99.7 4.2 2.5e-15 55.7 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EEQ69323.1 - 2.1e-23 81.4 3.9 2.8e-13 49.0 0.2 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EEQ69323.1 - 5.8e-16 57.7 0.1 5.1e-07 29.0 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 EEQ69323.1 - 1.4e-09 37.8 0.0 2.4e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Serglycin PF04360.7 EEQ69323.1 - 0.0024 17.5 0.3 0.0067 16.1 0.2 1.7 1 0 0 1 1 1 1 Serglycin F-box PF00646.28 EEQ69325.1 - 4.3e-06 26.2 0.0 1.4e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EEQ69325.1 - 0.0001 21.9 0.0 0.00027 20.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like DUF4192 PF13830.1 EEQ69325.1 - 2.4 7.7 6.2 3.9 7.0 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) A_deaminase PF00962.17 EEQ69326.1 - 4.2e-111 371.0 0.0 6.1e-111 370.4 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Peptidase_S10 PF00450.17 EEQ69334.1 - 1.6e-84 284.5 0.0 2.1e-84 284.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF3752 PF12572.3 EEQ69335.1 - 3.2e-43 147.4 7.5 3.2e-43 147.4 5.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Cut8_N PF14482.1 EEQ69335.1 - 8.1 6.5 10.0 0.37 10.8 2.0 2.5 3 0 0 3 3 3 0 Cut8 proteasome-binding domain ACOX PF01756.14 EEQ69336.1 - 1.6e-31 109.1 0.0 2.9e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EEQ69336.1 - 1.5e-18 67.3 0.0 2.9e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EEQ69336.1 - 5e-06 25.9 0.1 1.3e-05 24.6 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EEQ69336.1 - 0.00017 21.7 1.4 0.0015 18.6 0.2 2.7 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain LLC1 PF14945.1 EEQ69337.1 - 0.035 14.3 0.3 0.08 13.2 0.0 1.7 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Ribosomal_60s PF00428.14 EEQ69337.1 - 2.5 8.5 18.4 0.16 12.3 3.0 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein tRNA-synt_2c PF01411.14 EEQ69338.1 - 1.8e-216 719.7 0.0 2.4e-216 719.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EEQ69338.1 - 8.5e-18 63.9 0.6 2.3e-17 62.5 0.4 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EEQ69338.1 - 2e-08 33.8 1.2 5.6e-08 32.3 0.8 1.9 1 0 0 1 1 1 1 DHHA1 domain Pro_isomerase PF00160.16 EEQ69339.1 - 4.4e-49 166.6 0.9 4.9e-49 166.5 0.7 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3792 PF12670.2 EEQ69340.1 - 0.039 13.8 1.0 0.039 13.8 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Ank_2 PF12796.2 EEQ69341.1 - 1.2e-11 44.7 0.1 2.1e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ69341.1 - 2.4e-11 42.8 5.8 1.8e-05 24.2 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.19 EEQ69341.1 - 1.1e-10 41.3 2.3 1.6e-10 40.8 0.6 2.1 2 0 0 2 2 2 1 IPT/TIG domain Ank_4 PF13637.1 EEQ69341.1 - 9.6e-10 38.7 0.3 2.1e-09 37.6 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ69341.1 - 5.1e-09 35.5 0.9 0.0035 17.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EEQ69341.1 - 9e-08 32.1 3.5 3.3e-05 23.9 1.7 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) TRAPPC10 PF12584.3 EEQ69342.1 - 4.5e-38 130.0 0.0 7.6e-38 129.3 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 EEQ69342.1 - 0.00055 19.4 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 DUF2139 PF09910.4 EEQ69342.1 - 0.1 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2139) PH_2 PF08458.5 EEQ69343.1 - 0.0012 18.7 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 Plant pleckstrin homology-like region Attacin_N PF03768.10 EEQ69343.1 - 0.12 12.2 0.3 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 Attacin, N-terminal region Pkinase PF00069.20 EEQ69344.1 - 2e-26 92.7 0.0 5.3e-26 91.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ69344.1 - 3.7e-10 39.3 0.0 5.9e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase EcKinase PF02958.15 EEQ69344.1 - 0.052 12.6 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase RBFA PF02033.13 EEQ69345.1 - 0.023 14.7 0.3 0.045 13.7 0.1 1.6 1 1 0 1 1 1 0 Ribosome-binding factor A FA_desaturase PF00487.19 EEQ69348.1 - 1.3e-14 54.3 25.9 2.1e-14 53.6 17.8 1.5 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EEQ69348.1 - 4.4e-08 33.2 0.0 9.5e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Ank_2 PF12796.2 EEQ69349.1 - 9.3e-25 86.7 0.6 5.7e-18 65.0 0.2 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ69349.1 - 6.2e-23 79.4 5.8 1.4e-05 24.6 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EEQ69349.1 - 2.3e-19 69.3 0.3 1e-10 41.8 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ69349.1 - 3e-18 64.1 1.7 0.0021 18.1 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 EEQ69349.1 - 7.9e-14 51.3 5.8 0.0002 21.4 0.0 4.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) RVP PF00077.15 EEQ69349.1 - 7.8e-05 22.5 0.1 0.068 13.0 0.0 2.4 1 1 1 2 2 2 2 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EEQ69349.1 - 0.015 15.0 0.4 4.7 7.0 0.0 2.6 1 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EEQ69349.1 - 0.051 14.0 0.2 8.4 6.9 0.0 2.3 1 1 1 2 2 2 0 Aspartyl protease Rad51 PF08423.6 EEQ69350.1 - 1.8e-21 76.2 0.0 2.9e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EEQ69350.1 - 1.4e-11 44.1 0.0 3.7e-11 42.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EEQ69350.1 - 9.9e-06 24.8 0.2 9.9e-05 21.5 0.1 2.1 1 1 0 1 1 1 1 KaiC RecA PF00154.16 EEQ69350.1 - 0.00023 20.3 0.0 0.12 11.4 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein NACHT PF05729.7 EEQ69350.1 - 0.12 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 EEQ69350.1 - 0.14 12.3 0.0 0.43 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain Cu_amine_oxid PF01179.15 EEQ69351.1 - 7.4e-161 535.4 0.0 8.9e-161 535.2 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EEQ69351.1 - 8.6e-06 25.7 0.0 1.8e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EEQ69351.1 - 6.7e-05 22.8 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Dabb PF07876.7 EEQ69352.1 - 7.6e-19 67.9 0.0 8.5e-19 67.8 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain ABM PF03992.11 EEQ69352.1 - 0.053 13.5 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase MFS_1 PF07690.11 EEQ69353.1 - 2e-25 89.2 25.0 2e-25 89.2 17.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 EEQ69355.1 - 3.8e-14 52.1 0.0 6.7e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ69355.1 - 5.9e-08 32.5 8.1 1.1e-07 31.6 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4606 PF15379.1 EEQ69357.1 - 0.015 15.3 0.4 0.031 14.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) p450 PF00067.17 EEQ69358.1 - 4.4e-60 203.5 0.0 5.4e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EEQ69359.1 - 1.2e-34 119.5 25.5 1.2e-34 119.5 17.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.4 EEQ69359.1 - 0.033 14.1 0.3 0.033 14.1 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF1616 PF07760.6 EEQ69359.1 - 0.04 13.0 3.0 0.081 12.0 0.5 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1616) HLH PF00010.21 EEQ69362.1 - 4.2e-14 51.9 1.0 8e-14 51.0 0.7 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Serglycin PF04360.7 EEQ69362.1 - 0.63 9.7 7.0 6.9 6.3 0.6 2.6 2 0 0 2 2 2 0 Serglycin IU_nuc_hydro PF01156.14 EEQ69366.1 - 6.3e-48 163.5 0.0 4.1e-46 157.6 0.0 2.5 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase SURF4 PF02077.10 EEQ69367.1 - 2.6e-95 318.8 7.6 3e-95 318.6 5.3 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.7 EEQ69367.1 - 0.01 16.2 1.5 0.01 16.2 1.0 3.2 3 0 0 3 3 3 0 DoxX LSM PF01423.17 EEQ69370.1 - 5.9e-17 60.9 0.1 7.9e-17 60.5 0.1 1.2 1 0 0 1 1 1 1 LSM domain zf-B_box PF00643.19 EEQ69371.1 - 0.11 12.3 12.2 0.38 10.6 1.6 3.4 3 0 0 3 3 3 0 B-box zinc finger FYVE PF01363.16 EEQ69371.1 - 3.4 7.6 14.8 0.071 13.0 2.7 2.4 2 1 0 2 2 2 0 FYVE zinc finger WH2 PF02205.15 EEQ69372.1 - 1.4e-08 34.0 0.4 1.4e-08 34.0 0.3 2.2 2 0 0 2 2 2 1 WH2 motif Ribosomal_L1 PF00687.16 EEQ69374.1 - 4e-53 179.9 0.8 4.8e-53 179.7 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DEK_C PF08766.6 EEQ69374.1 - 0.28 11.0 0.1 0.28 11.0 0.0 2.6 3 0 0 3 3 3 0 DEK C terminal domain Acetyltransf_1 PF00583.19 EEQ69376.1 - 0.00014 21.8 0.0 0.00032 20.6 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EEQ69376.1 - 0.0022 18.0 0.1 0.51 10.4 0.0 2.6 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEQ69376.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 EEQ69376.1 - 0.13 12.3 0.0 0.33 11.1 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ69376.1 - 0.14 11.9 0.0 0.41 10.4 0.0 1.8 1 0 0 1 1 1 0 FR47-like protein CorA PF01544.13 EEQ69377.1 - 0.0002 20.5 0.6 0.0002 20.5 0.4 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Arf PF00025.16 EEQ69378.1 - 4.8e-79 263.6 0.1 5.9e-79 263.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EEQ69378.1 - 3e-15 55.9 0.0 3.7e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EEQ69378.1 - 2.7e-13 49.6 0.0 3.1e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EEQ69378.1 - 1e-12 47.5 1.5 1.1e-09 37.4 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EEQ69378.1 - 6e-11 41.9 0.0 6.8e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EEQ69378.1 - 2.2e-08 34.5 0.0 3.2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEQ69378.1 - 3.7e-06 26.8 0.0 5.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEQ69378.1 - 0.0045 16.4 0.1 0.037 13.4 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EEQ69378.1 - 0.01 14.8 0.3 0.024 13.7 0.1 1.5 1 1 0 2 2 2 0 6-phosphofructo-2-kinase AAA_33 PF13671.1 EEQ69378.1 - 0.042 13.7 0.2 0.12 12.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain DUF3405 PF11885.3 EEQ69381.1 - 1.8e-219 729.1 0.1 2.2e-219 728.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) AMP-binding PF00501.23 EEQ69382.1 - 4.6e-170 565.5 0.0 1.3e-88 297.1 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EEQ69382.1 - 1.4e-64 217.8 0.0 1.1e-25 90.1 0.0 4.2 3 1 0 3 3 3 3 Condensation domain PP-binding PF00550.20 EEQ69382.1 - 5.1e-17 61.8 0.4 7.3e-08 32.5 0.0 3.2 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEQ69382.1 - 1.9e-10 41.5 0.0 8.5e-06 26.6 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain ADH_N PF08240.7 EEQ69383.1 - 1.2e-06 28.2 0.0 2.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CMD PF02627.15 EEQ69383.1 - 0.00014 21.6 0.0 0.00034 20.3 0.0 1.7 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family CtnDOT_TraJ PF07863.6 EEQ69383.1 - 0.058 13.8 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon p450 PF00067.17 EEQ69384.1 - 1.9e-73 247.5 0.0 2.4e-73 247.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_3 PF01596.12 EEQ69385.1 - 1.9e-26 92.4 0.0 2.3e-18 65.9 0.0 2.0 1 1 1 2 2 2 2 O-methyltransferase Methyltransf_24 PF13578.1 EEQ69385.1 - 1.6e-07 32.1 0.0 2e-05 25.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ69385.1 - 1.4e-05 25.5 0.0 2.7e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ69385.1 - 3.1e-05 23.6 0.0 0.0002 21.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EEQ69385.1 - 0.00022 20.8 0.0 0.00031 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EEQ69385.1 - 0.03 14.0 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 EEQ69385.1 - 0.072 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MFS_1 PF07690.11 EEQ69386.1 - 6.1e-33 113.9 54.2 2.6e-30 105.3 26.0 3.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ69386.1 - 3.5e-05 22.5 13.5 3.5e-05 22.5 9.4 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter Sod_Cu PF00080.15 EEQ69387.1 - 4e-16 59.4 0.1 6.3e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) AP_endonuc_2 PF01261.19 EEQ69389.1 - 2.9e-15 56.1 0.1 1.3e-08 34.4 0.0 2.9 3 0 0 3 3 3 2 Xylose isomerase-like TIM barrel DUF1707 PF08044.6 EEQ69389.1 - 0.084 12.6 0.3 0.5 10.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) Choline_kinase PF01633.15 EEQ69390.1 - 1.9e-48 164.8 0.0 2.7e-47 161.1 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EEQ69390.1 - 9.3e-10 38.6 0.0 3e-09 36.9 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family CHORD PF04968.7 EEQ69391.1 - 7.9e-51 170.1 17.3 2.8e-27 94.7 2.3 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 EEQ69391.1 - 3.6e-11 43.4 0.0 5.3e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 CS domain HpcH_HpaI PF03328.9 EEQ69392.1 - 5.3e-36 123.5 0.0 6.4e-36 123.3 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF2156 PF09924.4 EEQ69392.1 - 0.025 13.4 0.0 0.05 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2156) PEP_mutase PF13714.1 EEQ69392.1 - 0.047 12.9 0.4 4.9 6.3 0.0 2.9 3 1 0 3 3 3 0 Phosphoenolpyruvate phosphomutase Fungal_trans PF04082.13 EEQ69395.1 - 5.1e-20 71.4 0.5 8.2e-20 70.7 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ69395.1 - 0.039 13.8 2.0 0.087 12.7 1.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Rifin_STEVOR PF02009.11 EEQ69396.1 - 0.011 15.3 1.1 0.015 14.9 0.8 1.2 1 0 0 1 1 1 0 Rifin/stevor family DUF929 PF06053.6 EEQ69396.1 - 0.076 12.0 1.4 0.1 11.6 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF929) DUF3753 PF12575.3 EEQ69396.1 - 0.7 9.7 6.1 1.6 8.5 4.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Acyl-CoA_dh_1 PF00441.19 EEQ69397.1 - 9.3e-33 113.4 0.3 1.4e-32 112.8 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EEQ69397.1 - 2.9e-20 71.5 2.4 5.7e-20 70.5 1.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EEQ69397.1 - 2.5e-11 44.1 0.8 2.2e-10 41.0 0.1 2.8 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EEQ69397.1 - 3.7e-07 30.4 0.2 5.4e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain 14-3-3 PF00244.15 EEQ69399.1 - 6.1e-09 35.3 0.1 1.2e-08 34.3 0.0 1.4 2 0 0 2 2 2 1 14-3-3 protein Myb_DNA-binding PF00249.26 EEQ69401.1 - 0.025 14.6 0.5 0.025 14.6 0.3 2.7 2 1 0 2 2 2 0 Myb-like DNA-binding domain Metallophos PF00149.23 EEQ69403.1 - 2e-07 30.5 4.4 4.2e-07 29.5 3.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3237 PF11578.3 EEQ69404.1 - 1.2e-47 160.9 0.0 1.4e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) GSG-1 PF07803.6 EEQ69404.1 - 0.049 13.2 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 GSG1-like protein PSI PF01437.20 EEQ69405.1 - 3.4e-05 23.8 8.3 3.4e-05 23.8 5.7 1.6 2 0 0 2 2 2 1 Plexin repeat EMP24_GP25L PF01105.19 EEQ69406.1 - 7.7e-45 152.8 0.0 9.1e-45 152.6 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Myb_DNA-bind_6 PF13921.1 EEQ69407.1 - 0.0005 20.1 2.1 0.021 14.9 0.2 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEQ69407.1 - 0.0011 18.9 1.8 0.13 12.3 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Med15 PF09606.5 EEQ69407.1 - 0.03 12.5 39.3 0.035 12.3 27.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 EEQ69407.1 - 0.083 11.1 43.3 0.11 10.7 30.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dicty_REP PF05086.7 EEQ69407.1 - 0.85 7.2 10.1 1 7.0 7.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Bul1_N PF04425.7 EEQ69407.1 - 2.8 6.3 15.1 0.42 9.1 7.3 1.7 2 0 0 2 2 2 0 Bul1 N terminus PP_M1 PF03012.9 EEQ69407.1 - 7.6 5.7 14.1 0.76 9.0 6.2 1.9 2 0 0 2 2 2 0 Phosphoprotein TraH_2 PF06871.6 EEQ69407.1 - 8 5.8 8.4 6.3 6.1 4.5 1.7 2 0 0 2 2 2 0 TraH_2 Glyco_hydro_17 PF00332.13 EEQ69408.1 - 4e-30 104.9 0.0 8.1e-29 100.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 DUF3394 PF11874.3 EEQ69409.1 - 5.4 6.5 7.2 3.4 7.1 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3394) APS_kinase PF01583.15 EEQ69411.1 - 1.1e-69 233.1 0.0 1.3e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EEQ69411.1 - 3.3e-06 27.0 0.0 6.9e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEQ69411.1 - 1.4e-05 25.4 0.0 2.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEQ69411.1 - 2.1e-05 25.3 0.0 2.8e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EEQ69411.1 - 0.0052 16.0 0.0 0.0082 15.3 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.1 EEQ69411.1 - 0.037 14.0 0.1 0.053 13.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EEQ69411.1 - 0.043 13.3 0.0 0.082 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain 6PF2K PF01591.13 EEQ69411.1 - 0.076 12.0 0.1 0.14 11.1 0.0 1.4 2 0 0 2 2 2 0 6-phosphofructo-2-kinase V-ATPase_C PF03223.10 EEQ69412.1 - 3.6e-117 391.4 0.0 4e-117 391.2 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C 4HBT PF03061.17 EEQ69413.1 - 1.4e-11 44.3 0.0 2.4e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Ligase_CoA PF00549.14 EEQ69414.1 - 1.8e-32 112.0 0.3 3.7e-17 62.3 0.0 2.5 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.14 EEQ69414.1 - 1.5e-17 63.9 1.6 2.3e-17 63.2 0.3 2.0 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 EEQ69414.1 - 1.9e-11 43.7 0.0 4.3e-09 36.1 0.0 2.5 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EEQ69414.1 - 0.0049 17.0 0.2 0.013 15.6 0.1 1.8 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.5 EEQ69414.1 - 0.061 12.6 0.0 0.71 9.2 0.0 2.2 1 1 0 1 1 1 0 ATP-grasp domain DUF605 PF04652.11 EEQ69415.1 - 0.19 11.0 22.9 0.33 10.2 15.9 1.4 1 0 0 1 1 1 0 Vta1 like Rad60-SLD PF11976.3 EEQ69416.1 - 8.2e-21 73.4 0.6 1.1e-20 73.1 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EEQ69416.1 - 2.3e-09 36.5 0.1 2.8e-09 36.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.7 EEQ69416.1 - 0.015 15.0 0.1 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) Nup84_Nup100 PF04121.8 EEQ69417.1 - 3.3e-58 196.9 3.1 7.5e-49 166.0 0.8 2.7 2 1 0 2 2 2 2 Nuclear pore protein 84 / 107 Daxx PF03344.10 EEQ69417.1 - 0.00066 18.3 21.9 0.00098 17.7 15.2 1.2 1 0 0 1 1 1 1 Daxx Family SDA1 PF05285.7 EEQ69417.1 - 0.0023 17.2 21.8 0.0037 16.5 15.1 1.3 1 0 0 1 1 1 1 SDA1 DUF2457 PF10446.4 EEQ69417.1 - 0.0051 15.6 23.9 0.0093 14.7 16.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Nop14 PF04147.7 EEQ69417.1 - 0.0072 14.3 23.4 0.012 13.5 16.2 1.4 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 EEQ69417.1 - 0.058 11.4 15.2 0.093 10.7 10.6 1.3 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 EEQ69417.1 - 1.5 6.8 17.6 3.1 5.7 12.2 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CAP_N PF01213.14 EEQ69418.1 - 0.17 11.1 13.1 0.2 10.8 9.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal E1-E2_ATPase PF00122.15 EEQ69419.1 - 8.1e-59 198.4 2.5 1.8e-58 197.2 1.7 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEQ69419.1 - 9e-45 152.4 6.6 9e-45 152.4 4.6 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEQ69419.1 - 3.9e-27 96.0 0.0 2.3e-26 93.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ69419.1 - 3.5e-20 71.7 0.0 7.1e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EEQ69419.1 - 7.6e-13 49.0 0.0 1.8e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEQ69419.1 - 3.4e-06 26.4 0.8 7.4e-06 25.3 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EEQ69419.1 - 1.3e-05 24.8 1.2 4.9e-05 23.0 0.3 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 EEQ69419.1 - 0.022 14.6 1.9 0.069 13.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) DUF2236 PF09995.4 EEQ69420.1 - 6.8e-12 45.2 1.8 9.3e-12 44.7 0.2 2.0 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) Aldedh PF00171.17 EEQ69421.1 - 6.1e-103 344.6 0.2 8.2e-103 344.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Tubulin PF00091.20 EEQ69422.1 - 2.4e-55 187.7 0.0 7.4e-55 186.0 0.0 1.8 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EEQ69422.1 - 2.3e-48 163.4 0.1 3.8e-48 162.6 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EEQ69422.1 - 0.00012 22.0 0.1 0.00047 20.1 0.0 2.0 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain RRM_1 PF00076.17 EEQ69423.1 - 1.9e-15 56.2 0.3 3.8e-07 29.6 0.1 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ69423.1 - 1.8e-11 43.8 0.1 1.2e-05 25.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ69423.1 - 1.7e-10 40.5 0.0 3.1e-07 30.1 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_60s PF00428.14 EEQ69423.1 - 0.019 15.3 0.9 0.057 13.8 0.1 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-C2H2_4 PF13894.1 EEQ69424.1 - 0.006 16.8 3.1 0.006 16.8 2.1 3.8 2 1 1 3 3 3 1 C2H2-type zinc finger DUF3770 PF12603.3 EEQ69424.1 - 0.0078 15.3 0.1 0.011 14.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3770) zf-C2H2 PF00096.21 EEQ69424.1 - 0.0087 16.3 1.7 0.0087 16.3 1.2 4.1 4 1 0 4 4 4 1 Zinc finger, C2H2 type BRE1 PF08647.6 EEQ69424.1 - 0.014 15.3 1.1 0.023 14.6 0.8 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase TMF_DNA_bd PF12329.3 EEQ69424.1 - 0.018 14.8 4.9 0.025 14.3 3.4 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding CENP-Q PF13094.1 EEQ69424.1 - 0.025 14.6 2.0 0.038 14.0 1.4 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-Di19 PF05605.7 EEQ69424.1 - 0.026 14.6 3.7 0.064 13.3 2.1 2.2 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 EEQ69424.1 - 0.037 14.3 12.4 1.4 9.3 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double domain DUF904 PF06005.7 EEQ69424.1 - 0.067 13.4 3.3 0.11 12.7 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF4164 PF13747.1 EEQ69424.1 - 0.069 13.2 3.2 0.1 12.7 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) PhoU PF01895.14 EEQ69424.1 - 0.095 13.1 0.2 0.15 12.5 0.1 1.3 1 0 0 1 1 1 0 PhoU domain ADIP PF11559.3 EEQ69424.1 - 0.13 12.2 4.1 0.19 11.6 2.8 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF1192 PF06698.6 EEQ69424.1 - 0.13 12.0 1.4 0.26 11.1 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) DUF3552 PF12072.3 EEQ69424.1 - 0.14 11.3 3.2 0.2 10.8 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) IncA PF04156.9 EEQ69424.1 - 0.44 10.1 3.7 0.62 9.6 2.5 1.2 1 0 0 1 1 1 0 IncA protein SlyX PF04102.7 EEQ69424.1 - 0.52 10.7 3.4 0.93 9.9 2.4 1.4 1 0 0 1 1 1 0 SlyX zf-MIZ PF02891.15 EEQ69424.1 - 8.8 5.9 9.9 5.5 6.5 0.1 2.9 2 1 0 2 2 2 0 MIZ/SP-RING zinc finger Pkinase PF00069.20 EEQ69428.1 - 2.2e-64 217.0 0.0 4.6e-64 216.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ69428.1 - 8.8e-34 116.7 0.0 7.7e-33 113.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ69428.1 - 2.2e-08 33.4 0.1 8.5e-07 28.2 0.1 2.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EEQ69428.1 - 0.00017 21.4 0.5 0.0037 17.0 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EEQ69428.1 - 0.0084 14.9 0.1 0.015 14.1 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.17 EEQ69428.1 - 0.11 11.8 0.3 0.22 10.8 0.2 1.4 1 0 0 1 1 1 0 RIO1 family Ank PF00023.25 EEQ69429.1 - 3.8e-06 26.4 0.3 1.2e-05 24.9 0.2 1.9 1 1 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 EEQ69429.1 - 8.3e-05 22.9 0.1 0.0013 19.1 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEQ69429.1 - 0.00037 20.7 0.1 0.00043 20.5 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EEQ69429.1 - 0.0017 18.3 0.1 0.0082 16.2 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EEQ69429.1 - 0.071 13.3 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) EF-1_beta_acid PF10587.4 EEQ69430.1 - 3.1e-12 46.4 4.3 3.1e-12 46.4 3.0 4.3 5 0 0 5 5 5 1 Eukaryotic elongation factor 1 beta central acidic region EF1_GNE PF00736.14 EEQ69430.1 - 2.9e-11 42.8 1.0 1.2e-10 40.9 0.7 2.0 1 1 0 1 1 1 1 EF-1 guanine nucleotide exchange domain YL1 PF05764.8 EEQ69430.1 - 0.011 15.3 1.1 0.011 15.3 0.7 2.1 2 0 0 2 2 2 0 YL1 nuclear protein GST_C_3 PF14497.1 EEQ69430.1 - 0.047 14.1 0.1 0.14 12.6 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain AAA_2 PF07724.9 EEQ69431.1 - 2.1e-46 157.9 0.0 5e-44 150.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EEQ69431.1 - 1.6e-26 91.9 0.1 6.9e-26 89.9 0.1 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EEQ69431.1 - 2.8e-19 69.6 0.4 3.5e-10 40.1 0.0 3.0 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEQ69431.1 - 3.5e-12 46.2 0.1 1.7e-07 31.0 0.0 3.1 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEQ69431.1 - 3.6e-09 36.8 2.1 0.0023 18.0 0.0 4.0 3 2 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EEQ69431.1 - 1.1e-07 32.0 15.5 0.0012 18.8 0.1 5.2 4 2 1 6 6 5 2 AAA ATPase domain Sigma54_activat PF00158.21 EEQ69431.1 - 1.7e-07 30.8 0.6 0.0008 18.9 0.1 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.7 EEQ69431.1 - 1.8e-05 24.4 0.1 0.14 11.8 0.0 2.7 2 0 0 2 2 2 2 NACHT domain IstB_IS21 PF01695.12 EEQ69431.1 - 3.5e-05 23.3 0.1 0.056 12.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 EEQ69431.1 - 0.0003 21.0 4.5 0.096 12.9 0.1 3.3 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 EEQ69431.1 - 0.00037 20.1 0.0 0.02 14.6 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 EEQ69431.1 - 0.00049 20.0 0.7 0.2 11.5 0.0 3.6 3 1 0 3 3 3 1 AAA domain MobB PF03205.9 EEQ69431.1 - 0.00052 19.7 0.0 0.2 11.3 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EEQ69431.1 - 0.00054 19.4 0.1 0.4 10.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.17 EEQ69431.1 - 0.00083 18.8 0.1 0.13 11.6 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Arch_ATPase PF01637.13 EEQ69431.1 - 0.00095 18.9 11.2 0.092 12.4 0.3 4.8 3 2 0 3 3 3 1 Archaeal ATPase AAA_17 PF13207.1 EEQ69431.1 - 0.0015 19.3 6.6 0.89 10.3 0.0 4.1 4 1 0 4 4 4 2 AAA domain TrwB_AAD_bind PF10412.4 EEQ69431.1 - 0.0016 17.1 0.2 0.13 10.8 0.0 2.6 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.22 EEQ69431.1 - 0.0018 18.5 1.1 0.69 10.2 0.0 3.2 3 0 0 3 3 3 1 ABC transporter RNA_helicase PF00910.17 EEQ69431.1 - 0.005 16.9 0.1 1.9 8.7 0.0 2.8 2 1 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 EEQ69431.1 - 0.0058 15.8 0.3 1.7 7.7 0.1 3.0 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Miro PF08477.8 EEQ69431.1 - 0.0088 16.5 0.1 1.1 9.8 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein PduV-EutP PF10662.4 EEQ69431.1 - 0.0093 15.4 0.0 0.53 9.7 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EEQ69431.1 - 0.012 14.7 0.1 5.5 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EEQ69431.1 - 0.013 14.5 0.0 0.76 8.8 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin UvrD-helicase PF00580.16 EEQ69431.1 - 0.016 14.5 3.5 0.15 11.3 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_24 PF13479.1 EEQ69431.1 - 0.016 14.7 0.0 0.5 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EEQ69431.1 - 0.021 14.4 5.7 0.26 10.8 0.0 4.2 4 1 1 5 5 4 0 AAA domain AAA_33 PF13671.1 EEQ69431.1 - 0.021 14.6 0.1 5.9 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF3333 PF11812.3 EEQ69431.1 - 0.025 14.5 1.1 0.56 10.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) ResIII PF04851.10 EEQ69431.1 - 0.025 14.4 2.3 5.2 6.8 0.0 3.2 3 1 1 4 4 3 0 Type III restriction enzyme, res subunit Myosin_tail_1 PF01576.14 EEQ69431.1 - 0.049 11.3 16.0 0.081 10.6 11.1 1.2 1 0 0 1 1 1 0 Myosin tail AAA_15 PF13175.1 EEQ69431.1 - 0.07 12.1 1.7 0.58 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain UPF0079 PF02367.12 EEQ69431.1 - 0.092 12.3 0.1 16 5.1 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF2664 PF10867.3 EEQ69431.1 - 0.15 12.7 6.2 8.4 7.0 1.5 3.7 4 0 0 4 4 3 0 Protein of unknown function (DUF2664) AAA_29 PF13555.1 EEQ69431.1 - 0.17 11.4 0.1 6.9 6.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain FlxA PF14282.1 EEQ69431.1 - 0.63 10.0 6.5 1.5 8.7 4.5 1.7 1 0 0 1 1 1 0 FlxA-like protein AAA_10 PF12846.2 EEQ69431.1 - 1.1 8.5 4.8 0.87 8.9 0.0 3.0 3 1 0 3 3 3 0 AAA-like domain Atg14 PF10186.4 EEQ69431.1 - 1.5 7.7 7.7 2.7 6.8 5.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 OEP PF02321.13 EEQ69431.1 - 3.4 7.2 12.4 8.6 5.9 8.6 1.6 1 0 0 1 1 1 0 Outer membrane efflux protein DUF87 PF01935.12 EEQ69431.1 - 6 6.6 9.8 47 3.6 0.1 3.5 4 0 0 4 4 3 0 Domain of unknown function DUF87 MutS_V PF00488.16 EEQ69432.1 - 6.5e-27 94.4 0.1 1.5e-23 83.4 0.0 2.4 2 0 0 2 2 2 2 MutS domain V MutS_III PF05192.13 EEQ69432.1 - 5.2e-18 65.5 0.0 7.7e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 MutS domain III Sas10 PF09368.5 EEQ69433.1 - 9.8e-30 102.5 8.3 9.8e-30 102.5 5.8 2.9 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EEQ69433.1 - 2.5e-17 62.8 0.6 1.8e-16 60.0 0.0 2.5 2 0 0 2 2 2 1 Sas10/Utp3/C1D family adh_short PF00106.20 EEQ69434.1 - 3.5e-20 72.5 0.0 4.9e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ69434.1 - 5.1e-07 29.5 0.4 8.2e-06 25.6 0.3 2.1 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EEQ69434.1 - 2.6e-06 27.5 0.5 0.00013 22.0 0.0 2.6 3 0 0 3 3 3 1 NADH(P)-binding adh_short_C2 PF13561.1 EEQ69434.1 - 0.00054 19.8 0.0 0.0009 19.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.14 EEQ69434.1 - 0.0024 16.9 0.0 0.0043 16.1 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 EEQ69434.1 - 0.0027 17.1 0.0 0.0047 16.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EEQ69434.1 - 0.0047 17.0 0.1 0.0088 16.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.16 EEQ69434.1 - 0.0076 16.1 0.1 0.011 15.5 0.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ApbA PF02558.11 EEQ69434.1 - 0.04 13.3 0.0 0.077 12.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EEQ69434.1 - 0.041 13.5 0.2 0.076 12.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LeuA_dimer PF08502.5 EEQ69434.1 - 0.11 12.3 0.6 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 LeuA allosteric (dimerisation) domain FA_hydroxylase PF04116.8 EEQ69436.1 - 1.6e-13 51.0 6.7 1.6e-13 51.0 4.7 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_L6e PF01159.14 EEQ69437.1 - 6.6e-38 129.2 0.5 6.6e-38 129.2 0.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L6e Proteasom_Rpn13 PF04683.8 EEQ69438.1 - 2.6e-27 94.6 0.0 3.9e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Ion_trans PF00520.26 EEQ69439.1 - 1.6e-78 262.5 66.8 1.4e-32 112.6 3.8 5.3 6 0 0 6 6 6 4 Ion transport protein EF-hand_1 PF00036.27 EEQ69439.1 - 0.0032 16.6 0.0 0.013 14.7 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EEQ69439.1 - 0.041 14.0 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair PKD_channel PF08016.7 EEQ69439.1 - 0.19 10.1 51.9 0.088 11.2 1.4 5.0 5 0 0 5 5 5 0 Polycystin cation channel JSRP PF15312.1 EEQ69439.1 - 0.65 9.9 2.4 1.1 9.2 0.0 2.6 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein SET PF00856.23 EEQ69441.1 - 5.9e-22 78.7 0.1 1.5e-21 77.3 0.0 1.7 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 EEQ69441.1 - 2.5e-14 53.3 5.2 1e-13 51.4 0.7 2.6 2 0 0 2 2 2 1 Pre-SET motif Pkinase PF00069.20 EEQ69442.1 - 1.5e-77 260.2 0.0 2.2e-77 259.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ69442.1 - 1.5e-40 138.9 0.0 3.7e-40 137.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EEQ69442.1 - 2.5e-17 62.0 0.2 4.5e-17 61.2 0.2 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 EEQ69442.1 - 4e-06 26.0 0.0 6.7e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEQ69442.1 - 3.8e-05 22.8 0.0 0.00014 20.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEQ69442.1 - 0.0011 18.8 0.1 0.016 14.9 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EEQ69442.1 - 0.012 14.9 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL WaaY PF06176.6 EEQ69442.1 - 0.013 14.7 0.1 0.022 14.0 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.17 EEQ69442.1 - 0.016 14.5 0.4 0.054 12.8 0.1 2.0 2 1 0 2 2 2 0 RIO1 family DUF1604 PF07713.8 EEQ69443.1 - 3.2e-39 132.5 2.2 3.2e-39 132.5 1.5 3.7 5 0 0 5 5 5 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EEQ69443.1 - 1.9e-07 30.7 1.5 4.4e-07 29.5 0.4 2.2 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EEQ69443.1 - 0.0071 16.1 0.2 0.0071 16.1 0.2 3.2 2 0 0 2 2 2 1 DExH-box splicing factor binding site ubiquitin PF00240.18 EEQ69444.1 - 0.00043 19.6 0.1 0.0012 18.1 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EEQ69444.1 - 0.0015 18.1 0.0 0.0034 17.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EEQ69444.1 - 0.0068 16.5 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Nop52 PF05997.7 EEQ69445.1 - 6.7e-23 81.2 0.0 3.9e-16 59.1 0.0 2.2 2 0 0 2 2 2 2 Nucleolar protein,Nop52 Nop14 PF04147.7 EEQ69445.1 - 5.4 4.8 8.2 6.6 4.5 5.7 1.3 1 0 0 1 1 1 0 Nop14-like family DAGK_cat PF00781.19 EEQ69446.1 - 7.3e-22 77.1 0.0 1.3e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Adaptin_N PF01602.15 EEQ69447.1 - 3.1e-96 322.7 12.3 6.2e-96 321.8 8.6 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.7 EEQ69447.1 - 4.9e-63 210.9 0.8 1.1e-62 209.8 0.5 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.1 EEQ69447.1 - 8.4e-62 206.6 0.0 2.6e-61 205.0 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.1 EEQ69447.1 - 1.5e-12 47.6 6.1 2.9e-07 30.6 0.0 4.6 3 1 1 4 4 4 3 HEAT repeats Cnd1 PF12717.2 EEQ69447.1 - 1.2e-05 25.2 9.7 0.017 14.9 0.0 4.1 3 2 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EEQ69447.1 - 0.00025 20.8 0.1 0.36 11.0 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EEQ69447.1 - 0.0055 17.1 3.8 0.15 12.5 0.0 4.4 4 1 1 5 5 5 2 HEAT-like repeat AP4E_app_platf PF14807.1 EEQ69447.1 - 0.026 14.7 0.1 0.13 12.4 0.1 2.3 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Arm PF00514.18 EEQ69447.1 - 0.05 13.4 0.0 3.1 7.7 0.0 3.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Mago_nashi PF02792.9 EEQ69448.1 - 1.3e-67 225.9 0.2 1.5e-67 225.7 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein Phage_portal_2 PF05136.8 EEQ69448.1 - 0.0075 14.8 0.0 0.0087 14.6 0.0 1.0 1 0 0 1 1 1 1 Phage portal protein, lambda family Vac_ImportDeg PF09783.4 EEQ69449.1 - 1.8e-69 232.7 3.0 2.3e-69 232.4 2.1 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Adeno_E1B_55K_N PF04623.7 EEQ69449.1 - 0.62 10.6 3.2 1.6 9.2 2.0 1.8 1 1 1 2 2 2 0 Adenovirus E1B protein N-terminus PAN_2 PF08276.6 EEQ69450.1 - 0.13 12.1 0.9 0.13 12.1 0.6 1.7 2 0 0 2 2 2 0 PAN-like domain MMgT PF10270.4 EEQ69451.1 - 9e-30 103.2 0.0 1e-29 103.0 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter Clat_adaptor_s PF01217.15 EEQ69453.1 - 4.7e-43 146.3 0.0 6.9e-43 145.7 0.0 1.2 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_L7Ae PF01248.21 EEQ69454.1 - 1e-21 76.2 3.4 4e-21 74.3 0.3 2.2 2 0 0 2 2 2 2 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLASP_N PF12348.3 EEQ69455.1 - 2.3e-05 23.8 1.4 0.00017 21.0 0.1 2.8 3 0 0 3 3 3 1 CLASP N terminal IncA PF04156.9 EEQ69455.1 - 0.0014 18.2 4.3 0.0014 18.2 3.0 2.1 2 0 0 2 2 2 1 IncA protein Adaptin_N PF01602.15 EEQ69455.1 - 0.0022 16.4 2.0 0.05 11.9 1.4 2.6 1 1 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 EEQ69455.1 - 0.0046 16.9 0.5 1.7 8.9 0.1 4.4 5 0 0 5 5 5 1 HEAT repeat TAN PF11640.3 EEQ69455.1 - 0.016 14.9 0.1 0.077 12.7 0.0 2.3 1 1 0 1 1 1 0 Telomere-length maintenance and DNA damage repair MMS19_N PF14500.1 EEQ69455.1 - 0.026 13.7 7.5 0.028 13.7 0.2 3.8 3 2 1 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II Proteasom_PSMB PF10508.4 EEQ69455.1 - 0.047 11.9 0.1 0.047 11.9 0.0 2.8 3 1 1 4 4 4 0 Proteasome non-ATPase 26S subunit Cnd1 PF12717.2 EEQ69455.1 - 0.15 11.8 2.0 0.28 11.0 0.0 2.3 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF3584 PF12128.3 EEQ69455.1 - 0.19 9.0 9.1 0.35 8.1 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6 PF04111.7 EEQ69455.1 - 0.31 10.0 19.3 0.14 11.2 9.4 2.6 3 0 0 3 3 3 0 Autophagy protein Apg6 ING PF12998.2 EEQ69455.1 - 0.82 9.9 10.4 0.28 11.4 4.4 2.3 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding HEAT_EZ PF13513.1 EEQ69455.1 - 1.5 9.4 6.7 8.2 7.0 0.1 4.0 3 1 0 4 4 4 0 HEAT-like repeat DUF641 PF04859.7 EEQ69455.1 - 1.7 8.3 10.8 9.5 5.9 6.0 2.7 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF972 PF06156.8 EEQ69455.1 - 4.8 7.5 8.4 20 5.5 5.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) WD40 PF00400.27 EEQ69456.1 - 2.3e-77 252.3 15.5 5.7e-12 45.0 0.0 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EEQ69456.1 - 1.1e-07 30.3 7.8 0.00046 18.4 0.4 5.1 3 2 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EEQ69456.1 - 0.00039 19.2 0.8 4 6.0 0.0 4.1 2 2 2 4 4 4 2 Nup133 N terminal like PLAC8 PF04749.12 EEQ69458.1 - 5.9e-19 68.6 5.5 3.8e-10 40.2 0.4 2.0 2 0 0 2 2 2 2 PLAC8 family ENTH PF01417.15 EEQ69460.1 - 1.6e-49 166.9 0.7 2.2e-49 166.4 0.0 1.6 2 0 0 2 2 2 1 ENTH domain ANTH PF07651.11 EEQ69460.1 - 0.00012 20.8 0.8 0.00017 20.4 0.0 1.6 2 0 0 2 2 2 1 ANTH domain DUF1720 PF08226.6 EEQ69460.1 - 0.0084 16.1 36.3 0.0084 16.1 25.2 6.2 1 1 3 4 4 4 1 Domain of unknown function (DUF1720) DUF4264 PF14084.1 EEQ69460.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) Chorismate_bind PF00425.13 EEQ69461.1 - 3.9e-89 298.3 0.0 5.7e-89 297.8 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EEQ69461.1 - 1.2e-28 99.8 0.0 2.3e-24 85.9 0.0 3.3 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region TFIIF_alpha PF05793.7 EEQ69466.1 - 0.0013 17.2 4.7 0.0013 17.2 3.3 1.6 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ATG16 PF08614.6 EEQ69466.1 - 0.0062 16.3 0.5 0.0062 16.3 0.4 2.3 2 2 0 2 2 2 1 Autophagy protein 16 (ATG16) Nop14 PF04147.7 EEQ69466.1 - 0.023 12.6 12.4 0.032 12.1 8.6 1.1 1 0 0 1 1 1 0 Nop14-like family SLBP_RNA_bind PF15247.1 EEQ69466.1 - 0.047 13.4 1.4 1.1 9.0 0.2 2.5 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain YL1 PF05764.8 EEQ69466.1 - 0.2 11.2 5.8 0.35 10.4 4.0 1.4 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.7 EEQ69466.1 - 0.4 9.9 10.7 0.7 9.1 7.4 1.5 1 0 0 1 1 1 0 SDA1 Nucleo_P87 PF07267.6 EEQ69466.1 - 0.43 9.2 8.7 0.46 9.1 5.3 1.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 PPP4R2 PF09184.6 EEQ69466.1 - 5.6 6.4 21.6 0.28 10.6 10.7 1.9 2 0 0 2 2 2 0 PPP4R2 LisH PF08513.6 EEQ69467.1 - 1.1e-06 28.2 0.0 2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 LisH WD40 PF00400.27 EEQ69467.1 - 6.5e-06 25.8 10.8 0.0017 18.1 0.0 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF1751 PF08551.5 EEQ69468.1 - 5e-28 97.3 4.4 9e-28 96.5 3.0 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EEQ69468.1 - 0.00033 20.6 8.0 0.00053 20.0 5.6 1.3 1 0 0 1 1 1 1 Rhomboid family DUF2476 PF10630.4 EEQ69468.1 - 0.024 14.5 4.9 0.037 13.9 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2476) DUF4149 PF13664.1 EEQ69468.1 - 0.4 10.7 7.7 0.18 11.8 1.1 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4149) MNHE PF01899.11 EEQ69468.1 - 4.7 6.8 8.8 0.65 9.6 2.8 1.9 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit L51_S25_CI-B8 PF05047.11 EEQ69469.1 - 4.5e-15 55.1 0.0 6.9e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain tRNA-synt_1 PF00133.17 EEQ69470.1 - 2.4e-36 124.9 0.0 4.2e-26 91.1 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EEQ69470.1 - 4.7e-17 61.7 0.1 5.3e-11 41.8 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EEQ69470.1 - 3.8e-12 46.1 0.1 8.9e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EEQ69470.1 - 5.4e-08 32.3 0.0 1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EEQ69470.1 - 0.12 11.0 0.0 0.25 9.9 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (K) MMR_HSR1 PF01926.18 EEQ69471.1 - 3.1e-06 27.1 0.0 1.1e-05 25.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EEQ69471.1 - 0.047 12.8 0.0 0.31 10.2 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Telomere_Sde2 PF13019.1 EEQ69472.1 - 9.1e-65 217.2 0.2 1.4e-64 216.7 0.1 1.3 1 0 0 1 1 1 1 Telomere stability and silencing LacI PF00356.16 EEQ69472.1 - 0.45 10.1 0.0 0.45 10.1 0.0 2.4 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family S10_plectin PF03501.10 EEQ69473.1 - 6.7e-40 134.8 0.1 9e-40 134.4 0.1 1.2 1 0 0 1 1 1 1 Plectin/S10 domain Peptidase_M20 PF01546.23 EEQ69474.1 - 1.3e-21 77.0 0.4 2.2e-21 76.2 0.3 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EEQ69474.1 - 0.00065 19.4 0.2 0.0015 18.2 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EEQ69474.1 - 0.004 16.9 0.0 0.0087 15.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 HIT PF01230.18 EEQ69475.1 - 1.6e-21 76.6 0.1 2.1e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EEQ69475.1 - 2.5e-12 47.0 0.0 3.6e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EEQ69475.1 - 0.0042 16.7 0.0 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CRAL_TRIO PF00650.15 EEQ69476.1 - 2.5e-38 131.0 0.0 4.9e-38 130.1 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EEQ69476.1 - 1.4e-14 53.9 0.1 4.7e-14 52.2 0.1 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EEQ69476.1 - 2e-08 34.2 0.0 4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Kringle PF00051.13 EEQ69476.1 - 0.068 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Kringle domain DASH_Dam1 PF08653.5 EEQ69477.1 - 1.5e-30 104.6 2.1 2.1e-30 104.2 1.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 UCH PF00443.24 EEQ69478.1 - 1.5e-57 194.8 1.6 1.8e-57 194.5 1.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEQ69478.1 - 3.8e-28 98.7 0.5 5.5e-28 98.2 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ytp1 PF10355.4 EEQ69481.1 - 3.2e-113 377.4 9.2 3.2e-113 377.4 6.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EEQ69481.1 - 5.2e-18 64.5 13.4 1.4e-09 37.4 0.3 4.0 2 1 1 3 3 3 3 Domain of unknown function (DUF2427) Hum_adeno_E3A PF05393.6 EEQ69481.1 - 0.021 14.5 3.4 0.11 12.1 0.3 2.8 3 0 0 3 3 3 0 Human adenovirus early E3A glycoprotein Rhomboid PF01694.17 EEQ69482.1 - 3e-12 46.7 11.2 3e-12 46.7 7.8 1.6 2 0 0 2 2 2 1 Rhomboid family Gaa1 PF04114.9 EEQ69483.1 - 2.6e-99 333.2 5.8 4.3e-99 332.5 4.0 1.3 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component PCI PF01399.22 EEQ69484.1 - 3.9e-09 36.7 0.0 7.8e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 PCI domain DUF3990 PF13151.1 EEQ69484.1 - 0.071 12.4 0.5 4.6 6.6 0.0 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF3990) NAD_binding_10 PF13460.1 EEQ69485.1 - 6.3e-16 58.9 0.0 8.6e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEQ69485.1 - 6.3e-14 51.9 0.1 1.2e-13 51.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EEQ69485.1 - 1.1e-12 47.7 0.0 1.4e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EEQ69485.1 - 6.6e-10 38.1 0.1 1.3e-09 37.2 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EEQ69485.1 - 7.4e-08 31.6 0.0 1.6e-06 27.2 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EEQ69485.1 - 4.8e-05 22.4 0.1 0.0059 15.5 0.0 2.9 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EEQ69485.1 - 0.00019 21.3 0.2 0.029 14.2 0.0 2.5 3 0 0 3 3 3 1 short chain dehydrogenase HIM1 PF08732.5 EEQ69485.1 - 0.008 14.6 0.0 0.011 14.1 0.0 1.2 1 0 0 1 1 1 1 HIM1 KR PF08659.5 EEQ69485.1 - 0.016 14.8 0.0 6.9 6.2 0.0 2.4 2 0 0 2 2 2 0 KR domain DDE_Tnp_1_3 PF13612.1 EEQ69485.1 - 0.046 13.4 0.0 0.098 12.3 0.0 1.5 2 0 0 2 2 2 0 Transposase DDE domain Saccharop_dh PF03435.13 EEQ69485.1 - 0.05 12.5 0.0 0.078 11.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_synthase PF02540.12 EEQ69485.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 NAD synthase HEM4 PF02602.10 EEQ69486.1 - 2.5e-31 108.7 0.0 9e-30 103.6 0.0 2.1 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD MSP1_C PF07462.6 EEQ69487.1 - 0.15 10.4 5.3 0.18 10.1 3.7 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Pkinase PF00069.20 EEQ69488.1 - 1.8e-69 233.7 0.0 2.2e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ69488.1 - 5.7e-31 107.5 0.0 7.2e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ69488.1 - 0.00079 18.4 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEQ69488.1 - 0.0022 17.1 0.1 0.0034 16.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ69488.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EEQ69488.1 - 0.042 12.6 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Sec23_trunk PF04811.10 EEQ69490.1 - 5.3e-70 235.5 0.0 1e-69 234.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EEQ69490.1 - 4.6e-24 83.8 0.0 4.9e-23 80.5 0.0 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EEQ69490.1 - 7.8e-18 63.7 4.3 1.3e-17 62.9 3.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EEQ69490.1 - 4.4e-17 62.3 0.0 1.1e-16 61.1 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EEQ69490.1 - 2.1e-06 27.3 0.0 4.6e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Hemerythrin PF01814.18 EEQ69491.1 - 3.4e-14 53.1 2.3 4.8e-14 52.6 1.6 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Peptidase_S46 PF10459.4 EEQ69491.1 - 0.0058 15.1 0.2 0.0063 14.9 0.1 1.0 1 0 0 1 1 1 1 Peptidase S46 adh_short PF00106.20 EEQ69492.1 - 1.5e-28 99.8 0.6 1.8e-28 99.5 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ69492.1 - 2.6e-28 99.4 0.0 3.1e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ69492.1 - 1.3e-14 54.2 0.5 1.9e-14 53.7 0.3 1.2 1 0 0 1 1 1 1 KR domain Kinesin PF00225.18 EEQ69493.1 - 5e-82 275.2 1.1 1.1e-81 274.1 0.8 1.6 1 0 0 1 1 1 1 Kinesin motor domain HHH PF00633.18 EEQ69493.1 - 2.3e-06 26.9 0.9 0.078 12.7 0.0 3.4 3 0 0 3 3 3 2 Helix-hairpin-helix motif HHH_5 PF14520.1 EEQ69493.1 - 0.00015 21.8 0.5 0.00077 19.5 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_3 PF12836.2 EEQ69493.1 - 0.0069 16.3 0.2 2.8 7.9 0.1 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif MFS_1 PF07690.11 EEQ69494.1 - 4.2e-30 104.6 50.8 5.4e-18 64.8 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RPE65 PF03055.10 EEQ69495.1 - 1.2e-97 327.4 0.0 1.5e-97 327.1 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Hemerythrin PF01814.18 EEQ69497.1 - 9.5e-09 35.5 0.5 1.5e-08 34.8 0.4 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain AIM24 PF01987.12 EEQ69498.1 - 2.9e-42 144.5 0.0 3.9e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Synapsin_N PF10581.4 EEQ69498.1 - 0.023 14.4 0.1 0.047 13.5 0.1 1.5 1 0 0 1 1 1 0 Synapsin N-terminal DUF4402 PF14352.1 EEQ69498.1 - 0.026 14.9 0.1 0.063 13.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) ABC_membrane PF00664.18 EEQ69499.1 - 7.4e-37 127.2 10.5 1e-36 126.7 7.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EEQ69499.1 - 1.5e-33 115.9 0.0 3e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EEQ69499.1 - 2.7e-07 30.8 0.1 0.0041 17.1 0.0 2.5 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 EEQ69499.1 - 4.5e-06 26.0 0.0 0.0036 16.5 0.0 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EEQ69499.1 - 6.6e-05 23.7 0.0 0.00017 22.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEQ69499.1 - 8.1e-05 22.6 0.1 0.00047 20.1 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEQ69499.1 - 0.00096 19.3 0.0 0.0056 16.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EEQ69499.1 - 0.0034 16.8 0.0 0.011 15.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EEQ69499.1 - 0.0034 16.8 0.1 0.008 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EEQ69499.1 - 0.0041 16.6 0.1 0.012 15.0 0.0 1.7 1 1 0 1 1 1 1 AAA-like domain ABC_ATPase PF09818.4 EEQ69499.1 - 0.0046 15.6 0.0 0.082 11.4 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_14 PF13173.1 EEQ69499.1 - 0.0081 16.0 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EEQ69499.1 - 0.018 14.2 0.0 0.036 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EEQ69499.1 - 0.019 15.3 0.2 0.057 13.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EEQ69499.1 - 0.021 15.1 0.0 0.085 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EEQ69499.1 - 0.036 14.0 0.0 0.23 11.4 0.0 2.3 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EEQ69499.1 - 0.04 13.4 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.1 EEQ69499.1 - 0.05 13.4 0.0 0.18 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EEQ69499.1 - 0.094 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA PF00004.24 EEQ69499.1 - 0.099 12.8 0.0 0.67 10.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1190 PF06693.6 EEQ69501.1 - 0.019 15.0 0.7 0.022 14.8 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1190) Vac14_Fig4_bd PF11916.3 EEQ69502.1 - 2.7e-83 277.5 6.0 2.7e-83 277.5 4.2 1.9 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EEQ69502.1 - 5.5e-45 151.7 0.0 4.2e-43 145.6 0.0 3.4 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EEQ69502.1 - 3.9e-10 38.9 0.6 0.00041 20.1 0.0 6.3 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 EEQ69502.1 - 1.6e-09 37.9 1.2 0.0013 19.1 0.0 5.2 3 1 1 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.1 EEQ69502.1 - 7e-07 29.4 1.2 0.0054 16.9 0.0 4.8 5 1 0 5 5 5 1 HEAT repeats DUF4195 PF13836.1 EEQ69502.1 - 0.0065 16.1 4.2 0.24 11.0 0.7 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4195) Arm PF00514.18 EEQ69502.1 - 0.016 15.0 0.0 11 5.9 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EEQ69502.1 - 0.07 12.4 0.0 13 5.0 0.0 3.6 3 2 1 4 4 4 0 CLASP N terminal SNF2_N PF00176.18 EEQ69503.1 - 4.3e-67 226.0 0.0 5.8e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EEQ69503.1 - 2.9e-62 209.9 2.4 5.9e-62 208.9 1.7 1.4 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 EEQ69503.1 - 4e-12 45.8 0.0 9.6e-12 44.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EEQ69503.1 - 1.4e-05 24.0 0.0 6.3e-05 21.9 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.1 EEQ69503.1 - 0.025 14.7 0.0 0.17 12.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain Mito_carr PF00153.22 EEQ69504.1 - 5.5e-52 173.4 1.7 7.5e-21 73.6 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Rab5ip PF07019.7 EEQ69504.1 - 0.052 13.6 1.9 0.089 12.9 0.0 2.3 2 1 0 2 2 2 0 Rab5-interacting protein (Rab5ip) zf-C2H2_jaz PF12171.3 EEQ69505.1 - 2.4e-09 37.0 2.0 2.4e-09 37.0 1.4 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 EEQ69505.1 - 0.008 15.7 0.5 0.016 14.7 0.3 1.5 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_2 PF12756.2 EEQ69505.1 - 0.034 14.2 0.6 0.051 13.6 0.4 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Tna_leader PF08053.6 EEQ69505.1 - 0.096 12.0 0.1 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Tryptophanese operon leader peptide Ribosomal_L2 PF00181.18 EEQ69505.1 - 0.11 12.4 0.6 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 Ribosomal Proteins L2, RNA binding domain zf-met PF12874.2 EEQ69505.1 - 1.2 9.4 3.8 0.38 11.0 0.7 1.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Aconitase PF00330.15 EEQ69506.1 - 6.9e-176 585.2 0.0 2.4e-175 583.5 0.0 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EEQ69506.1 - 3.3e-47 159.8 0.0 5.5e-47 159.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Lactamase_B PF00753.22 EEQ69507.1 - 1.6e-26 93.1 2.6 2.5e-26 92.5 1.8 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EEQ69507.1 - 1e-05 25.2 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_transf_20 PF00982.16 EEQ69508.1 - 4.3e-201 668.4 0.0 4.9e-201 668.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EEQ69508.1 - 0.0061 16.0 0.4 0.023 14.1 0.1 2.0 2 0 0 2 2 2 1 Starch synthase catalytic domain Ribosomal_S17 PF00366.15 EEQ69509.1 - 3.8e-06 26.8 0.4 7.3e-06 25.9 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 CMV_1a PF12467.3 EEQ69509.1 - 0.025 14.9 1.2 0.06 13.7 0.8 1.6 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DUF605 PF04652.11 EEQ69509.1 - 0.085 12.2 9.8 0.13 11.6 6.8 1.3 1 0 0 1 1 1 0 Vta1 like DUF2360 PF10152.4 EEQ69509.1 - 0.11 12.7 5.2 0.17 12.1 3.6 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Pex14_N PF04695.8 EEQ69509.1 - 0.2 11.6 8.0 0.3 11.1 5.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAP PF07174.6 EEQ69509.1 - 0.24 10.6 10.7 0.32 10.2 7.4 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Pol_alpha_B_N PF08418.5 EEQ69509.1 - 0.45 10.0 9.0 0.61 9.5 6.3 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal AAA PF00004.24 EEQ69510.1 - 1.8e-25 89.6 0.0 4.9e-25 88.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EEQ69510.1 - 1.4e-07 31.2 0.0 5.7e-06 26.1 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EEQ69510.1 - 4.6e-06 26.8 0.1 6.8e-05 23.0 0.1 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEQ69510.1 - 7.6e-05 21.8 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EEQ69510.1 - 0.0014 18.5 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EEQ69510.1 - 0.0017 17.8 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 EEQ69510.1 - 0.0028 17.6 0.7 0.036 14.0 0.0 3.0 3 1 1 4 4 4 1 AAA ATPase domain AAA_5 PF07728.9 EEQ69510.1 - 0.0029 17.3 0.0 0.0073 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EEQ69510.1 - 0.0033 16.6 0.0 0.0068 15.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 EEQ69510.1 - 0.0042 15.8 0.0 0.007 15.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EEQ69510.1 - 0.0055 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ69510.1 - 0.009 15.7 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EEQ69510.1 - 0.012 15.6 0.1 0.066 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EEQ69510.1 - 0.039 13.3 0.0 0.12 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EEQ69510.1 - 0.049 14.4 0.1 0.12 13.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain DUF815 PF05673.8 EEQ69510.1 - 0.056 12.3 0.0 0.09 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 EEQ69510.1 - 0.059 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EEQ69510.1 - 0.059 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EEQ69510.1 - 0.12 12.0 0.0 0.34 10.5 0.0 1.8 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.11 EEQ69510.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.21 EEQ69510.1 - 0.15 11.5 0.0 0.39 10.1 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain Mito_carr PF00153.22 EEQ69511.1 - 2.2e-70 232.4 3.7 1.6e-24 85.3 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein IBR PF01485.16 EEQ69514.1 - 6e-23 80.4 47.9 5.6e-12 45.3 4.5 4.5 3 1 1 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 EEQ69514.1 - 4.2e-05 23.4 8.0 4.2e-05 23.4 5.5 4.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ69514.1 - 0.00018 21.2 7.6 0.00018 21.2 5.2 3.6 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 EEQ69514.1 - 0.00027 20.5 41.1 0.0009 18.8 3.2 4.7 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) UN_NPL4 PF11543.3 EEQ69514.1 - 0.005 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-C3HC4_4 PF15227.1 EEQ69514.1 - 0.044 13.6 28.2 0.085 12.7 1.4 4.6 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EEQ69514.1 - 0.1 12.3 42.5 0.022 14.4 6.3 3.7 3 0 0 3 3 3 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 EEQ69514.1 - 7.5 6.3 27.9 0.16 11.7 1.3 3.9 3 1 0 3 3 3 0 RING-type zinc-finger Mog1 PF04603.7 EEQ69515.1 - 1.7e-17 63.6 0.0 1.6e-14 54.0 0.0 2.3 2 0 0 2 2 2 2 Ran-interacting Mog1 protein NYN PF01936.13 EEQ69516.1 - 0.0006 20.1 0.0 0.01 16.0 0.0 2.5 1 1 0 1 1 1 1 NYN domain HSP9_HSP12 PF04119.7 EEQ69517.1 - 2.3e-30 104.4 10.2 2.3e-30 104.4 7.0 2.0 2 0 0 2 2 2 1 Heat shock protein 9/12 Tombus_movement PF05318.7 EEQ69517.1 - 0.21 12.2 2.2 0.3 11.7 1.5 1.2 1 0 0 1 1 1 0 Tombusvirus movement protein YtxH PF12732.2 EEQ69517.1 - 0.24 11.7 5.1 0.6 10.5 3.6 1.7 1 1 0 1 1 1 0 YtxH-like protein TarH PF02203.10 EEQ69518.1 - 0.0043 16.9 0.9 1.3 8.8 0.0 2.3 2 0 0 2 2 2 2 Tar ligand binding domain homologue Nsp1_C PF05064.8 EEQ69518.1 - 0.04 13.5 2.0 0.24 11.0 0.1 2.3 2 1 0 2 2 2 0 Nsp1-like C-terminal region ING PF12998.2 EEQ69518.1 - 0.047 13.9 1.6 0.16 12.2 0.1 2.5 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding RmuC PF02646.11 EEQ69518.1 - 0.083 11.7 3.2 0.17 10.7 0.2 2.2 2 0 0 2 2 2 0 RmuC family Rabaptin PF03528.10 EEQ69518.1 - 1.7 8.6 6.2 0.24 11.3 0.2 2.4 3 0 0 3 3 3 0 Rabaptin APG6 PF04111.7 EEQ69518.1 - 1.8 7.5 9.4 0.21 10.6 0.7 2.5 1 1 2 3 3 3 0 Autophagy protein Apg6 Spc24 PF08286.6 EEQ69518.1 - 3.3 7.4 5.7 3.7 7.2 0.5 2.6 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 COG6 PF06419.6 EEQ69519.1 - 2.2e-233 775.9 2.4 2.5e-233 775.7 1.7 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.6 EEQ69519.1 - 0.29 10.9 3.2 1.6 8.5 1.1 2.8 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-F_leu_zip PF10473.4 EEQ69519.1 - 0.66 9.8 5.3 1.5 8.7 3.6 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NIF3 PF01784.13 EEQ69520.1 - 2.5e-58 197.5 0.0 3.2e-58 197.1 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Histone PF00125.19 EEQ69522.1 - 1.7e-05 24.8 0.1 2.5e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 BolA PF01722.13 EEQ69523.1 - 5.9e-22 77.4 0.0 7.3e-22 77.1 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Redoxin PF08534.5 EEQ69524.1 - 3.9e-31 107.5 0.0 4.6e-31 107.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EEQ69524.1 - 9e-09 35.0 0.0 1.1e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family HSF_DNA-bind PF00447.12 EEQ69526.1 - 1.3e-38 131.2 0.7 1.3e-38 131.2 0.5 1.9 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.19 EEQ69526.1 - 2.1e-20 72.7 0.1 4e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain DUF972 PF06156.8 EEQ69526.1 - 0.015 15.6 0.8 0.042 14.2 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CENP-Q PF13094.1 EEQ69526.1 - 0.025 14.6 6.7 0.059 13.3 4.7 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 EEQ69526.1 - 5.3 6.5 7.5 12 5.3 5.2 1.6 1 1 0 1 1 1 0 IncA protein PI-PLC-X PF00388.14 EEQ69527.1 - 6.4e-12 45.0 0.1 1e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain HNH_2 PF13391.1 EEQ69528.1 - 0.00023 20.8 1.9 0.0011 18.7 0.2 3.0 2 1 1 3 3 3 1 HNH endonuclease W2 PF02020.13 EEQ69529.1 - 2.2e-18 65.9 3.7 2.2e-18 65.9 2.6 2.6 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 EEQ69529.1 - 3.7e-13 48.3 7.6 0.00019 20.7 0.5 3.6 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EEQ69529.1 - 3.9e-10 39.1 6.6 0.00028 20.3 0.6 3.4 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase DUF1069 PF06370.6 EEQ69529.1 - 0.056 12.8 0.3 0.13 11.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1069) Nucleoplasmin PF03066.10 EEQ69529.1 - 3.1 7.3 15.8 5.8 6.4 7.2 2.4 2 0 0 2 2 2 0 Nucleoplasmin DUF2457 PF10446.4 EEQ69529.1 - 5.2 5.6 13.9 5.5 5.6 6.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) SprT-like PF10263.4 EEQ69530.1 - 4.5e-56 188.8 0.7 6.9e-56 188.2 0.5 1.3 1 0 0 1 1 1 1 SprT-like family DUF4379 PF14311.1 EEQ69530.1 - 0.024 14.4 5.4 0.12 12.2 3.7 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4379) Peptidase_MA_2 PF13485.1 EEQ69530.1 - 0.069 13.2 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Peptidase MA superfamily Nop14 PF04147.7 EEQ69530.1 - 7.4 4.3 11.5 16 3.2 7.9 1.5 1 0 0 1 1 1 0 Nop14-like family Glyco_hydro_72 PF03198.9 EEQ69531.1 - 1.5e-133 444.6 6.2 1.9e-133 444.3 4.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EEQ69531.1 - 1e-10 41.9 2.6 3.6e-08 33.7 0.7 3.2 2 1 1 3 3 3 2 X8 domain Glucan_synthase PF02364.10 EEQ69534.1 - 0 1462.3 0.0 0 1461.9 0.0 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EEQ69534.1 - 6.8e-40 135.6 0.9 1.5e-39 134.5 0.6 1.6 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aminotran_1_2 PF00155.16 EEQ69535.1 - 1e-32 113.5 0.0 1.1e-32 113.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EEQ69535.1 - 0.034 12.4 0.1 0.11 10.7 0.0 1.7 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_17 PF00332.13 EEQ69536.1 - 4.9e-05 22.5 0.4 0.00014 21.0 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 CorC_HlyC PF03471.12 EEQ69537.1 - 0.028 14.2 0.2 0.14 11.9 0.1 1.9 1 1 0 1 1 1 0 Transporter associated domain DUF4075 PF13294.1 EEQ69537.1 - 0.35 10.9 5.7 0.47 10.5 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4075) DUF2013 PF09431.5 EEQ69539.1 - 6.8e-32 110.1 2.3 6.8e-32 110.1 1.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) p450 PF00067.17 EEQ69540.1 - 1.9e-20 72.8 0.0 7e-20 70.9 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_47 PF01532.15 EEQ69541.1 - 5.9e-183 608.6 0.0 6.8e-183 608.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 APG9 PF04109.11 EEQ69542.1 - 1e-168 561.0 2.1 1.3e-168 560.6 1.4 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 RasGAP PF00616.14 EEQ69543.1 - 1.2e-45 155.6 0.0 3.2e-45 154.2 0.0 1.7 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EEQ69543.1 - 0.00078 19.2 0.1 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain Tropomyosin PF00261.15 EEQ69543.1 - 0.065 12.3 0.3 0.13 11.3 0.2 1.4 1 0 0 1 1 1 0 Tropomyosin DNA_methylase PF00145.12 EEQ69544.1 - 5.3e-34 117.8 0.0 9.6e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 EEQ69544.1 - 4.5e-10 39.3 0.2 0.00065 19.4 0.0 2.7 2 1 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.3 EEQ69544.1 - 0.11 12.1 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain WD40 PF00400.27 EEQ69545.1 - 2.1e-15 55.8 1.5 0.0025 17.6 0.1 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat COQ9 PF08511.6 EEQ69547.1 - 5e-24 83.6 0.2 7.3e-24 83.0 0.1 1.2 1 0 0 1 1 1 1 COQ9 AA_permease_2 PF13520.1 EEQ69549.1 - 4.1e-51 173.8 47.7 4.9e-51 173.5 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ69549.1 - 7.3e-26 90.5 38.6 1.1e-25 89.9 26.7 1.2 1 0 0 1 1 1 1 Amino acid permease FmdA_AmdA PF03069.10 EEQ69550.1 - 7.3e-55 186.1 0.0 1.9e-28 99.2 0.0 2.4 1 1 1 2 2 2 2 Acetamidase/Formamidase family RRM_1 PF00076.17 EEQ69554.1 - 3e-55 183.7 0.0 2.7e-18 65.3 0.0 3.4 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ69554.1 - 1.9e-45 152.7 0.0 3.6e-16 58.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ69554.1 - 3.7e-27 93.9 0.0 3.6e-08 33.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EEQ69554.1 - 3.6e-05 23.4 0.1 1.3 8.8 0.0 4.0 3 2 0 3 3 3 2 Limkain b1 RRM_3 PF08777.6 EEQ69554.1 - 4.3e-05 23.3 0.0 1.2 9.0 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif DUF1777 PF08648.7 EEQ69554.1 - 0.0041 16.8 11.5 0.0066 16.2 7.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) ATP-grasp_2 PF08442.5 EEQ69554.1 - 0.0075 15.6 0.0 0.19 11.0 0.0 2.8 3 0 0 3 3 3 1 ATP-grasp domain RebB PF11747.3 EEQ69555.1 - 0.067 13.0 0.8 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 Killing trait TrkH PF02386.11 EEQ69557.1 - 5.5e-108 360.6 8.5 6.6e-108 360.4 5.9 1.1 1 0 0 1 1 1 1 Cation transport protein PH PF00169.24 EEQ69559.1 - 1.1e-11 44.8 0.1 2.4e-11 43.7 0.1 1.6 1 0 0 1 1 1 1 PH domain Prominin PF05478.6 EEQ69559.1 - 0.037 11.5 0.2 0.053 11.0 0.1 1.1 1 0 0 1 1 1 0 Prominin Tim17 PF02466.14 EEQ69561.1 - 5.3e-15 55.5 6.2 8e-15 55.0 4.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RPT PF13446.1 EEQ69562.1 - 1.6e-49 165.1 1.4 4.4e-20 70.8 0.4 4.5 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.24 EEQ69562.1 - 4.2e-47 160.5 0.0 1.1e-46 159.1 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEQ69562.1 - 1.4e-09 37.7 0.4 1.1e-06 28.2 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase CoA_trans PF01144.18 EEQ69563.1 - 4.8e-102 339.7 2.4 1.1e-62 211.0 0.6 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Med3 PF11593.3 EEQ69564.1 - 0.0001 21.6 8.0 0.0001 21.6 5.5 1.0 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Phage_GPD PF05954.6 EEQ69564.1 - 0.012 14.7 0.7 0.015 14.4 0.5 1.1 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) DUF2360 PF10152.4 EEQ69564.1 - 0.028 14.6 6.0 0.033 14.4 4.1 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) PRCC PF10253.4 EEQ69564.1 - 0.029 15.0 5.3 0.032 14.9 3.7 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Retinal PF15449.1 EEQ69564.1 - 0.055 11.1 12.0 0.061 10.9 8.3 1.0 1 0 0 1 1 1 0 Retinal protein NUDE_C PF04880.8 EEQ69564.1 - 0.078 13.3 5.1 0.1 12.9 3.5 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Ndc1_Nup PF09531.5 EEQ69564.1 - 0.15 10.4 3.7 0.17 10.3 2.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.8 EEQ69564.1 - 0.22 11.3 4.6 0.22 11.3 3.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C4H2 PF10146.4 EEQ69564.1 - 0.29 11.1 4.8 0.33 10.9 3.3 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Suf PF05843.9 EEQ69564.1 - 0.32 10.6 6.2 0.37 10.4 4.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CENP-R PF06729.7 EEQ69564.1 - 0.35 10.5 5.1 0.53 9.9 3.5 1.2 1 0 0 1 1 1 0 Kinetochore component, CENP-R Pex14_N PF04695.8 EEQ69564.1 - 0.45 10.5 8.7 0.54 10.3 6.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1180 PF06679.7 EEQ69564.1 - 1.6 8.5 5.4 2.2 8.1 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) YppG PF14179.1 EEQ69564.1 - 1.9 9.1 12.4 6.3 7.4 8.6 1.8 1 1 0 1 1 1 0 YppG-like protein PAT1 PF09770.4 EEQ69564.1 - 2.9 6.0 11.8 3 5.9 8.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MSA-2c PF12238.3 EEQ69564.1 - 3.2 7.3 7.5 4.3 6.9 5.2 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF605 PF04652.11 EEQ69564.1 - 3.4 6.9 14.3 3.8 6.8 9.9 1.1 1 0 0 1 1 1 0 Vta1 like DUF2370 PF10176.4 EEQ69565.1 - 5.8e-88 294.1 0.0 8.1e-88 293.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF2561 PF10812.3 EEQ69565.1 - 0.094 12.3 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Zip PF02535.17 EEQ69567.1 - 0.11 11.4 4.5 0.18 10.8 3.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter MSP1_C PF07462.6 EEQ69567.1 - 0.58 8.4 1.2 0.84 7.9 0.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Macoilin PF09726.4 EEQ69567.1 - 4.1 5.5 8.2 5.9 5.0 5.7 1.1 1 0 0 1 1 1 0 Transmembrane protein WSC PF01822.14 EEQ69568.1 - 3.4e-08 33.3 1.8 3.4e-08 33.3 1.2 1.7 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.5 EEQ69568.1 - 7.6e-07 28.3 0.0 2.3e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4366 PF14283.1 EEQ69568.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF1191 PF06697.7 EEQ69568.1 - 0.011 14.5 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Tox-GHH2 PF15635.1 EEQ69568.1 - 0.11 12.8 0.0 0.39 11.1 0.0 1.9 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 CDP-OH_P_transf PF01066.16 EEQ69570.1 - 4.7e-11 42.8 2.6 4.7e-11 42.8 1.8 1.6 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Gar1 PF04410.9 EEQ69571.1 - 6.6e-42 142.5 0.6 2e-41 141.0 0.0 1.8 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region tRNA-synt_2b PF00587.20 EEQ69572.1 - 3.5e-42 143.9 0.2 6.2e-42 143.1 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEQ69572.1 - 3.9e-15 55.5 0.1 8.5e-15 54.4 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EEQ69572.1 - 2.6e-11 43.2 0.0 5.1e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EEQ69572.1 - 0.00049 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 TGS domain Fungal_trans PF04082.13 EEQ69575.1 - 3.9e-27 94.7 0.0 8.9e-27 93.5 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ69575.1 - 6.7e-10 38.7 13.1 1.2e-09 37.8 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M41 PF01434.13 EEQ69576.1 - 2.2e-74 249.5 0.0 3.4e-74 248.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EEQ69576.1 - 2.4e-42 144.2 0.0 5.6e-42 143.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EEQ69576.1 - 5.4e-07 29.7 0.1 1.2e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 EEQ69576.1 - 0.00029 20.5 0.1 0.0044 16.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEQ69576.1 - 0.0006 19.9 0.3 0.23 11.6 0.1 3.0 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EEQ69576.1 - 0.0031 18.3 0.0 0.013 16.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEQ69576.1 - 0.0041 16.1 0.0 0.012 14.6 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EEQ69576.1 - 0.0055 16.4 0.5 0.02 14.6 0.4 1.9 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 EEQ69576.1 - 0.0076 15.0 0.1 0.014 14.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 EEQ69576.1 - 0.013 15.4 0.2 0.13 12.2 0.1 2.4 1 1 1 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.12 EEQ69576.1 - 0.034 13.5 0.0 0.08 12.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EEQ69576.1 - 0.036 13.4 1.4 0.17 11.2 0.2 2.4 2 1 1 3 3 3 0 AAA domain AAA_2 PF07724.9 EEQ69576.1 - 0.039 13.8 0.1 0.15 11.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EEQ69576.1 - 0.1 12.5 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EEQ69576.1 - 0.1 12.4 0.0 0.29 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF1295 PF06966.7 EEQ69577.1 - 5.3e-37 127.3 3.9 8e-37 126.7 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Crystall PF00030.14 EEQ69577.1 - 0.087 12.7 0.6 1.5 8.7 0.1 2.3 1 1 1 2 2 2 0 Beta/Gamma crystallin ICMT PF04140.9 EEQ69577.1 - 0.43 10.8 4.0 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PrgI PF12666.2 EEQ69577.1 - 0.75 9.9 3.7 4.3 7.5 0.2 3.1 3 0 0 3 3 3 0 PrgI family protein Topoisom_bac PF01131.15 EEQ69578.1 - 7.4e-88 295.0 0.0 9e-88 294.7 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EEQ69578.1 - 6e-20 71.0 0.0 1.5e-19 69.8 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Myosin_tail_1 PF01576.14 EEQ69579.1 - 0.00011 20.0 13.0 0.00011 20.0 9.0 3.1 2 1 0 2 2 2 1 Myosin tail Tropomyosin_1 PF12718.2 EEQ69579.1 - 0.0096 15.7 1.7 0.0096 15.7 1.2 5.6 3 2 3 6 6 6 1 Tropomyosin like Reo_sigmaC PF04582.7 EEQ69579.1 - 0.41 9.7 30.4 0.12 11.5 2.8 4.8 3 2 2 5 5 5 0 Reovirus sigma C capsid protein DUF869 PF05911.6 EEQ69579.1 - 0.75 7.9 47.6 0.11 10.6 7.4 3.5 1 1 3 4 4 4 0 Plant protein of unknown function (DUF869) DUF812 PF05667.6 EEQ69579.1 - 3 6.2 50.0 0.29 9.6 8.5 4.4 1 1 3 4 4 4 0 Protein of unknown function (DUF812) IncA PF04156.9 EEQ69579.1 - 3.2 7.3 53.3 0.021 14.4 2.8 5.6 2 2 1 3 3 3 0 IncA protein DUF1515 PF07439.6 EEQ69579.1 - 5.9 6.7 26.2 0.41 10.4 0.7 6.4 4 3 2 7 7 7 0 Protein of unknown function (DUF1515) DUF2353 PF09789.4 EEQ69579.1 - 9.2 5.4 36.7 0.046 12.9 4.9 4.0 2 2 0 4 4 4 0 Uncharacterized coiled-coil protein (DUF2353) Hrs_helical PF12210.3 EEQ69579.1 - 9.6 6.5 12.0 0.077 13.2 0.3 3.6 3 3 2 5 5 5 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Ank_2 PF12796.2 EEQ69580.1 - 3.1e-28 97.9 0.1 1.7e-08 34.7 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ69580.1 - 4.8e-25 86.0 0.6 8.9e-05 22.1 0.0 7.0 6 1 1 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 EEQ69580.1 - 1.4e-19 68.1 0.1 0.0031 17.6 0.0 6.1 5 1 1 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 EEQ69580.1 - 7e-19 67.8 0.1 1.9e-05 25.0 0.1 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ69580.1 - 5.7e-07 29.5 1.0 0.2 11.9 0.2 4.3 2 2 2 4 4 4 2 Ankyrin repeats (many copies) EzrA PF06160.7 EEQ69581.1 - 0.0051 15.0 3.9 0.011 13.9 2.7 1.5 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA RILP PF11461.3 EEQ69581.1 - 0.0075 16.3 0.0 0.031 14.4 0.0 2.1 1 0 0 1 1 1 1 Rab interacting lysosomal protein DUF4349 PF14257.1 EEQ69581.1 - 0.055 12.6 0.2 0.94 8.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Flu_NS2 PF00601.14 EEQ69581.1 - 0.14 12.3 0.3 0.14 12.3 0.2 2.9 3 1 1 4 4 4 0 Influenza non-structural protein (NS2) DUF848 PF05852.6 EEQ69581.1 - 0.57 10.0 8.2 0.84 9.4 0.5 2.4 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) K-box PF01486.12 EEQ69581.1 - 0.74 9.6 8.3 5 6.9 0.0 3.4 2 1 2 4 4 4 0 K-box region Cast PF10174.4 EEQ69581.1 - 0.82 7.6 10.2 1.8 6.5 6.8 1.6 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Baculo_PEP_C PF04513.7 EEQ69581.1 - 0.99 9.2 3.5 8.5 6.1 0.1 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.2 EEQ69581.1 - 5.8 6.7 10.3 0.57 10.0 2.2 2.2 2 0 0 2 2 2 0 Tropomyosin like DUF4149 PF13664.1 EEQ69582.1 - 1.7e-26 92.1 2.4 4.7e-26 90.7 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Ku PF02735.11 EEQ69583.1 - 1e-26 93.6 0.0 1.7e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EEQ69583.1 - 7.5e-22 77.8 0.0 1.7e-21 76.7 0.0 1.6 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 EEQ69583.1 - 2.4e-15 56.4 0.0 9e-15 54.6 0.0 2.0 2 0 0 2 2 2 1 Ku C terminal domain like Ku_C PF03730.9 EEQ69583.1 - 0.48 10.9 5.6 0.37 11.3 0.2 3.5 3 1 2 5 5 5 0 Ku70/Ku80 C-terminal arm PX PF00787.19 EEQ69584.1 - 5.1e-16 58.4 0.0 1.2e-15 57.3 0.0 1.6 2 0 0 2 2 2 1 PX domain SNARE PF05739.14 EEQ69584.1 - 0.00024 20.7 5.1 0.00062 19.3 3.5 1.7 1 0 0 1 1 1 1 SNARE domain BCIP PF13862.1 EEQ69584.1 - 0.011 15.2 0.3 0.021 14.3 0.2 1.4 1 0 0 1 1 1 0 p21-C-terminal region-binding protein SPATA24 PF15175.1 EEQ69584.1 - 0.29 10.8 5.6 1.2 8.8 3.8 1.9 1 1 0 1 1 1 0 Spermatogenesis-associated protein 24 Abhydrolase_5 PF12695.2 EEQ69585.1 - 0.00016 21.4 0.0 0.00027 20.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EEQ69585.1 - 0.00033 20.2 0.0 0.00059 19.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EEQ69585.1 - 0.00035 20.5 0.0 0.00068 19.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EEQ69585.1 - 0.00049 19.4 0.1 0.00087 18.6 0.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) UPF0227 PF05728.7 EEQ69585.1 - 0.0005 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.20 EEQ69585.1 - 0.00062 19.3 0.0 0.0017 17.9 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.15 EEQ69585.1 - 0.038 14.2 0.4 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_1 PF00561.15 EEQ69585.1 - 0.052 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2305 PF10230.4 EEQ69585.1 - 0.092 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) SIP1 PF04938.7 EEQ69586.1 - 0.12 11.6 0.3 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF3381 PF11861.3 EEQ69586.1 - 2 7.8 6.7 2.7 7.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) tRNA-synt_2 PF00152.15 EEQ69587.1 - 2.6e-73 246.7 0.0 4.3e-73 246.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EEQ69587.1 - 2.3e-05 24.1 0.1 5e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Peripla_BP_3 PF13377.1 EEQ69587.1 - 0.019 14.9 0.3 0.037 14.0 0.2 1.5 1 0 0 1 1 1 0 Periplasmic binding protein-like domain DUF1570 PF07607.6 EEQ69587.1 - 0.089 12.7 0.1 0.49 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1570) PcfJ PF14284.1 EEQ69587.1 - 0.36 10.3 2.4 3.7 7.0 0.0 2.5 2 0 0 2 2 2 0 PcfJ-like protein Hydrolase_6 PF13344.1 EEQ69588.1 - 4.7e-25 87.4 0.0 7.7e-25 86.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ69588.1 - 2.6e-13 49.4 0.0 1.1e-12 47.5 0.0 2.0 1 1 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EEQ69588.1 - 7.4e-06 26.3 0.8 0.35 11.0 0.0 4.3 2 2 1 4 4 4 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEQ69588.1 - 0.00019 21.9 0.0 0.25 11.7 0.0 2.8 2 2 0 2 2 2 2 haloacid dehalogenase-like hydrolase F-box-like PF12937.2 EEQ69589.1 - 7.5e-10 38.3 4.3 9.6e-10 38.0 1.4 2.3 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 EEQ69589.1 - 0.0001 21.9 9.3 0.0083 15.8 0.0 4.6 3 1 3 6 6 6 4 Leucine rich repeat LRR_4 PF12799.2 EEQ69589.1 - 0.018 14.6 7.3 9.1 6.0 0.0 5.2 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) F-box PF00646.28 EEQ69589.1 - 0.084 12.5 0.3 0.084 12.5 0.2 3.2 3 0 0 3 3 3 0 F-box domain Adaptin_N PF01602.15 EEQ69590.1 - 1.1e-112 377.0 0.7 1.5e-112 376.6 0.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EEQ69590.1 - 1.1e-60 203.7 1.1 2.3e-60 202.7 0.7 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EEQ69590.1 - 7.4e-16 58.2 5.2 4.4e-05 23.6 0.0 6.5 2 2 4 6 6 6 4 HEAT repeats HEAT_PBS PF03130.11 EEQ69590.1 - 0.0002 21.5 1.7 13 6.6 0.0 5.2 4 0 0 4 4 4 2 PBS lyase HEAT-like repeat HEAT PF02985.17 EEQ69590.1 - 0.00045 20.0 7.5 0.68 10.1 0.1 6.5 6 0 0 6 6 6 1 HEAT repeat Alpha_adaptin_C PF02296.11 EEQ69590.1 - 0.014 15.3 0.1 0.048 13.6 0.0 1.9 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain HEAT_EZ PF13513.1 EEQ69590.1 - 0.59 10.6 8.0 0.28 11.7 0.3 4.1 5 0 0 5 5 5 0 HEAT-like repeat Phosducin PF02114.11 EEQ69591.1 - 5e-12 45.1 0.0 6e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Phosducin bZIP_1 PF00170.16 EEQ69592.1 - 7.2e-06 25.8 14.0 1.2e-05 25.1 9.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor TMF_TATA_bd PF12325.3 EEQ69592.1 - 0.006 16.3 5.1 0.01 15.5 3.6 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding bZIP_Maf PF03131.12 EEQ69592.1 - 0.0097 16.1 8.7 0.019 15.2 6.1 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF2353 PF09789.4 EEQ69592.1 - 0.012 14.8 1.7 0.019 14.2 1.2 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Glutaredoxin2_C PF04399.8 EEQ69592.1 - 0.041 13.4 1.2 0.078 12.5 0.8 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain GAS PF13851.1 EEQ69592.1 - 0.043 13.0 6.0 0.063 12.4 4.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HALZ PF02183.13 EEQ69592.1 - 0.18 11.5 2.5 0.3 10.8 0.8 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper V_ATPase_I PF01496.14 EEQ69592.1 - 0.25 9.1 0.9 0.31 8.8 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.10 EEQ69592.1 - 0.27 11.1 17.2 0.38 10.6 10.9 1.9 1 1 1 2 2 2 0 Basic region leucine zipper DUF972 PF06156.8 EEQ69592.1 - 0.29 11.4 2.1 0.44 10.9 0.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Bap31 PF05529.7 EEQ69592.1 - 5.6 6.3 5.8 8.2 5.8 4.0 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like MFS_1 PF07690.11 EEQ69595.1 - 7.6e-39 133.4 28.8 7.6e-39 133.4 19.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ69595.1 - 5.1e-12 45.1 16.8 9.2e-12 44.2 11.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 EEQ69595.1 - 0.0058 16.3 0.2 0.028 14.1 0.2 2.2 1 0 0 1 1 1 1 MFS_1 like family Glyco_hydro_47 PF01532.15 EEQ69596.1 - 7.8e-169 562.0 0.0 9e-169 561.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TORC_N PF12884.2 EEQ69596.1 - 0.019 15.4 0.0 0.057 13.9 0.0 1.8 1 0 0 1 1 1 0 Transducer of regulated CREB activity, N terminus Pkinase PF00069.20 EEQ69598.1 - 4.6e-38 130.8 0.0 5.6e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ69598.1 - 4.1e-14 52.2 0.0 5.5e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ69598.1 - 1.2e-05 25.1 0.0 0.0019 17.9 0.0 2.3 1 1 0 2 2 2 2 Phosphotransferase enzyme family Fungal_trans PF04082.13 EEQ69599.1 - 9.3e-25 86.9 0.3 2e-24 85.8 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ69599.1 - 0.00096 19.0 6.8 0.0017 18.1 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1445 PF07286.7 EEQ69600.1 - 4.1e-17 62.1 0.0 6.1e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Hydantoinase_B PF02538.9 EEQ69601.1 - 2.9e-196 652.8 0.0 3.6e-196 652.4 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EEQ69601.1 - 3.7e-97 324.9 0.0 1.2e-96 323.2 0.0 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EEQ69601.1 - 5.1e-55 185.6 1.4 3.1e-52 176.6 0.0 3.4 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region Kelch_5 PF13854.1 EEQ69602.1 - 2.1e-29 100.9 0.6 1.3e-08 34.5 0.1 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_1 PF01344.20 EEQ69602.1 - 7.6e-29 99.0 0.1 1.6e-12 46.7 0.2 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 EEQ69602.1 - 4.1e-27 93.7 5.8 3.4e-09 36.3 0.5 5.6 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.1 EEQ69602.1 - 4.6e-27 93.5 11.2 6.9e-07 29.2 0.1 6.1 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EEQ69602.1 - 3.2e-24 84.0 3.7 1.8e-11 43.6 0.3 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 EEQ69602.1 - 7.5e-20 69.8 2.5 3.4e-09 36.0 0.2 5.7 5 0 0 5 5 5 4 Kelch motif Raptor_N PF14538.1 EEQ69604.1 - 1.6e-64 216.4 0.0 2.8e-64 215.6 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EEQ69604.1 - 9.4e-08 31.6 7.4 0.43 10.5 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat HEAT PF02985.17 EEQ69604.1 - 0.00068 19.5 1.0 0.8 9.9 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat BBS2_Mid PF14783.1 EEQ69604.1 - 0.0012 18.6 0.4 0.062 13.0 0.2 2.6 1 1 1 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Peptidase_C14 PF00656.17 EEQ69604.1 - 0.0032 17.1 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Atx10homo_assoc PF09759.4 EEQ69604.1 - 0.15 11.8 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain zf-RING_2 PF13639.1 EEQ69607.1 - 1.5e-13 50.3 5.5 2.4e-13 49.6 3.8 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EEQ69607.1 - 2.2e-11 43.3 0.0 5.8e-11 41.9 0.0 1.8 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 EEQ69607.1 - 4.7e-09 36.1 5.7 7.7e-09 35.4 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEQ69607.1 - 1.8e-08 34.3 1.2 3.2e-08 33.5 0.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EEQ69607.1 - 2.7e-08 33.3 3.8 4.3e-08 32.6 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ69607.1 - 6.1e-08 32.2 3.1 9.3e-08 31.6 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ69607.1 - 1.1e-07 31.4 2.6 1.7e-07 30.8 1.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EEQ69607.1 - 0.0012 18.6 0.3 0.0023 17.7 0.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EEQ69607.1 - 0.033 13.9 3.3 0.079 12.6 2.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EEQ69607.1 - 0.091 12.6 2.4 0.2 11.5 1.7 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EEQ69607.1 - 0.097 12.6 2.5 0.24 11.3 1.8 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EEQ69607.1 - 0.39 10.8 4.3 0.74 9.9 3.0 1.5 1 0 0 1 1 1 0 RING-variant domain EI24 PF07264.6 EEQ69608.1 - 0.0043 16.5 8.7 0.014 14.8 6.0 1.8 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) LysM PF01476.15 EEQ69609.1 - 9.5e-07 28.6 0.0 1.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 LysM domain Y_phosphatase3 PF13350.1 EEQ69610.1 - 1.9e-08 34.7 0.0 4.5e-08 33.5 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family DUF3562 PF12085.3 EEQ69610.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) FHA PF00498.21 EEQ69611.1 - 1.3e-16 60.4 0.1 4.2e-16 58.8 0.0 1.9 2 0 0 2 2 2 1 FHA domain DegS PF05384.6 EEQ69611.1 - 0.014 14.6 1.3 0.014 14.6 0.9 2.1 2 0 0 2 2 2 0 Sensor protein DegS bZIP_1 PF00170.16 EEQ69611.1 - 0.021 14.7 6.1 0.1 12.5 1.0 2.9 2 0 0 2 2 2 0 bZIP transcription factor Mnd1 PF03962.10 EEQ69611.1 - 0.044 13.4 14.1 0.19 11.3 0.2 2.9 3 0 0 3 3 3 0 Mnd1 family TBPIP PF07106.8 EEQ69611.1 - 0.086 12.3 6.4 1.4 8.4 2.3 2.5 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3391 PF11871.3 EEQ69611.1 - 0.33 11.1 6.1 1.9 8.6 1.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF972 PF06156.8 EEQ69611.1 - 0.99 9.7 10.9 0.71 10.2 1.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF972) TPR_MLP1_2 PF07926.7 EEQ69611.1 - 1 9.1 15.4 0.83 9.4 1.4 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.5 EEQ69611.1 - 1.5 8.9 5.9 21 5.2 1.2 2.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Myosin_tail_1 PF01576.14 EEQ69611.1 - 4.1 4.9 16.6 0.25 9.0 0.9 2.5 3 0 0 3 3 3 0 Myosin tail Romo1 PF10247.4 EEQ69612.1 - 1.3e-27 95.8 13.2 1.7e-27 95.4 9.2 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Alpha_GJ PF03229.8 EEQ69614.1 - 0.077 13.3 11.3 0.085 13.1 7.8 1.1 1 0 0 1 1 1 0 Alphavirus glycoprotein J MGC-24 PF05283.6 EEQ69614.1 - 3.9 7.2 11.7 5 6.8 8.1 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) TMEM125 PF15109.1 EEQ69616.1 - 0.026 14.6 0.9 0.026 14.6 0.7 1.8 2 0 0 2 2 2 0 TMEM125 protein family LRR_4 PF12799.2 EEQ69617.1 - 5.9e-12 44.9 4.6 9.8e-10 37.8 0.7 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEQ69617.1 - 4.5e-11 42.3 2.3 7.1e-10 38.4 0.7 2.4 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 EEQ69617.1 - 5.3e-07 28.7 8.4 0.12 12.4 0.1 4.7 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 EEQ69617.1 - 0.0008 19.2 5.4 1.6 9.2 0.0 4.2 4 0 0 4 4 4 2 Leucine rich repeat Arb2 PF09757.4 EEQ69618.1 - 4e-37 127.3 0.1 5.8e-37 126.8 0.1 1.2 1 0 0 1 1 1 1 Arb2 domain RebB PF11747.3 EEQ69618.1 - 0.046 13.6 3.0 0.09 12.6 2.1 1.5 1 0 0 1 1 1 0 Killing trait Ribosomal_S14 PF00253.16 EEQ69619.1 - 5.7e-17 60.8 1.5 5.6e-16 57.6 0.3 2.1 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e QLQ PF08880.6 EEQ69619.1 - 0.11 11.9 1.1 0.47 9.9 0.1 2.2 2 0 0 2 2 2 0 QLQ Coatomer_b_Cpla PF14806.1 EEQ69619.1 - 0.12 12.0 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform ATP-synt_J PF04911.7 EEQ69620.1 - 4.7e-27 93.1 1.1 5.1e-27 93.0 0.7 1.0 1 0 0 1 1 1 1 ATP synthase j chain DASH_Spc19 PF08287.6 EEQ69621.1 - 2.7e-55 186.1 2.9 3.6e-55 185.7 2.0 1.2 1 0 0 1 1 1 1 Spc19 COG5 PF10392.4 EEQ69621.1 - 5.7 6.9 8.9 12 5.8 0.7 3.1 2 1 1 3 3 3 0 Golgi transport complex subunit 5 IFP_35_N PF07334.8 EEQ69621.1 - 8.7 6.4 8.7 23 5.0 2.6 2.8 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Rsm22 PF09243.5 EEQ69622.1 - 2.7e-28 98.7 0.0 3.1e-27 95.3 0.0 2.6 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Rogdi_lz PF10259.4 EEQ69623.1 - 1.3e-80 270.4 0.0 1.5e-80 270.2 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Mito_fiss_reg PF05308.6 EEQ69623.1 - 0.093 12.0 0.2 0.34 10.2 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator SUR7 PF06687.7 EEQ69624.1 - 6.3e-38 130.4 1.8 7.3e-38 130.2 1.2 1.0 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EEQ69624.1 - 2.4e-05 24.0 2.6 2.4e-05 24.0 1.8 2.0 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 EEQ69624.1 - 0.011 15.3 8.4 0.011 15.3 5.8 1.9 2 1 0 2 2 2 0 Amastin surface glycoprotein Clc-like PF07062.7 EEQ69624.1 - 0.68 9.1 10.3 0.25 10.5 4.6 1.9 1 1 1 2 2 2 0 Clc-like HSP70 PF00012.15 EEQ69625.1 - 4e-75 252.9 0.5 7.6e-75 252.0 0.0 1.5 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EEQ69625.1 - 1.5e-07 30.3 0.0 2.3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.3 EEQ69625.1 - 0.02 13.7 0.0 0.89 8.3 0.0 2.2 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Hydantoinase_A PF01968.13 EEQ69625.1 - 0.028 13.5 0.1 0.55 9.2 0.1 2.3 1 1 1 2 2 2 0 Hydantoinase/oxoprolinase PBP1_TM PF14812.1 EEQ69625.1 - 0.078 13.2 3.6 0.17 12.2 2.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BRAP2 PF07576.7 EEQ69625.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 BRCA1-associated protein 2 Sigma70_ner PF04546.8 EEQ69625.1 - 0.22 11.1 3.1 0.29 10.7 0.9 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region Rpp20 PF12328.3 EEQ69626.1 - 1e-52 177.6 13.9 2.2e-52 176.5 9.7 1.5 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EEQ69626.1 - 1.3e-24 85.5 1.5 2.3e-24 84.7 1.0 1.4 1 0 0 1 1 1 1 Alba PEP-utilisers_N PF05524.8 EEQ69626.1 - 0.11 12.2 2.4 1.4 8.6 0.3 2.2 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal hDGE_amylase PF14701.1 EEQ69626.1 - 0.15 10.8 2.7 0.31 9.9 1.9 1.5 1 1 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Syntaxin-6_N PF09177.6 EEQ69626.1 - 0.28 11.6 8.4 3 8.3 0.5 2.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal CMV_1a PF12467.3 EEQ69626.1 - 0.55 10.5 12.4 0.036 14.4 3.9 2.1 1 1 1 2 2 2 0 Cucumber mosaic virus 1a protein family DUF2514 PF10721.4 EEQ69626.1 - 1.2 8.8 7.9 0.49 10.0 4.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) PhzC-PhzF PF02567.11 EEQ69630.1 - 8.7e-23 80.9 0.7 1e-12 47.8 0.1 2.3 2 1 0 2 2 2 2 Phenazine biosynthesis-like protein SPX PF03105.14 EEQ69633.1 - 1.3e-06 28.4 3.7 1.5e-06 28.2 2.6 1.3 1 0 0 1 1 1 1 SPX domain Acyl-CoA_dh_1 PF00441.19 EEQ69634.1 - 1.6e-30 106.2 0.2 2.3e-30 105.6 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EEQ69634.1 - 3.3e-11 43.7 0.1 1.3e-10 41.8 0.0 2.1 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EEQ69634.1 - 2.6e-07 30.0 0.2 5.7e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EEQ69634.1 - 0.0004 20.6 0.0 0.00068 19.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UDP-g_GGTase PF06427.6 EEQ69635.1 - 1.4e-69 233.6 0.0 2.6e-69 232.7 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EEQ69635.1 - 0.00016 21.0 0.0 0.0003 20.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Myb_DNA-binding PF00249.26 EEQ69637.1 - 5.1e-14 52.0 3.8 7.8e-06 25.8 0.0 3.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEQ69637.1 - 6.7e-13 48.5 2.7 1.7e-09 37.6 0.0 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EEQ69637.1 - 0.023 14.7 1.4 0.12 12.5 1.0 2.3 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain HpaP PF09483.5 EEQ69637.1 - 0.043 13.7 1.3 0.081 12.8 0.9 1.4 1 0 0 1 1 1 0 Type III secretion protein (HpaP) DUF1431 PF07248.7 EEQ69637.1 - 0.077 12.9 3.3 0.18 11.7 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1431) HTH_38 PF13936.1 EEQ69637.1 - 0.09 12.3 0.1 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MADF_DNA_bdg PF10545.4 EEQ69637.1 - 0.19 11.9 0.3 0.19 11.9 0.2 2.7 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Amidohydro_1 PF01979.15 EEQ69638.1 - 3.2e-22 79.6 0.0 9.3e-21 74.8 0.0 2.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EEQ69638.1 - 2.7e-18 66.9 0.5 1.2e-14 55.0 0.5 2.6 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EEQ69638.1 - 3.6e-09 36.3 0.1 9.4e-09 34.9 0.1 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EEQ69638.1 - 1.4e-05 24.5 0.0 0.024 13.8 0.0 2.7 2 1 1 3 3 3 2 Amidohydrolase family Vma12 PF11712.3 EEQ69639.1 - 3.9e-36 123.8 0.0 5.3e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Prefoldin PF02996.12 EEQ69640.1 - 3.7e-29 100.8 0.0 5e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit MAD PF05557.8 EEQ69640.1 - 0.0097 14.0 0.6 0.016 13.3 0.1 1.5 2 0 0 2 2 2 1 Mitotic checkpoint protein Prefoldin_2 PF01920.15 EEQ69640.1 - 0.029 14.1 0.2 0.16 11.7 0.0 2.1 2 1 0 2 2 2 0 Prefoldin subunit CENP-Q PF13094.1 EEQ69640.1 - 0.09 12.8 2.0 0.09 12.8 0.4 1.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit HR1 PF02185.11 EEQ69640.1 - 0.12 12.0 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Hr1 repeat GRAM PF02893.15 EEQ69641.1 - 1.6e-27 94.7 0.8 3.2e-17 61.7 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 EEQ69641.1 - 3.8e-25 88.2 0.0 7.2e-25 87.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 EEQ69641.1 - 8.4e-14 51.6 0.0 2.1e-12 47.1 0.1 2.8 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EEQ69641.1 - 8.9e-07 29.1 0.6 2.1e-06 27.9 0.1 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EEQ69641.1 - 5.3e-05 23.2 0.1 0.0002 21.3 0.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 EEQ69641.1 - 0.0022 17.8 0.0 0.0053 16.6 0.0 1.6 1 0 0 1 1 1 1 PH domain UDPGT PF00201.13 EEQ69641.1 - 0.014 13.9 0.0 0.024 13.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Prenylcys_lyase PF07156.9 EEQ69643.1 - 2e-44 152.0 0.0 3.9e-31 108.2 0.0 2.3 2 1 0 2 2 2 2 Prenylcysteine lyase Amino_oxidase PF01593.19 EEQ69643.1 - 2e-14 53.5 0.0 3.1e-13 49.6 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EEQ69643.1 - 5.9e-11 42.2 0.0 1.5e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEQ69643.1 - 7.3e-05 21.8 0.0 0.00086 18.2 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEQ69643.1 - 0.0046 16.8 0.0 0.067 13.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEQ69643.1 - 0.038 14.0 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEQ69643.1 - 0.054 13.2 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding ImcF-related_N PF14331.1 EEQ69644.1 - 0.0082 15.0 0.2 0.025 13.4 0.1 1.7 2 0 0 2 2 2 1 ImcF-related N-terminal domain DUF4510 PF14971.1 EEQ69644.1 - 1.1 9.4 5.3 3.9 7.6 3.7 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4510) ACOX PF01756.14 EEQ69645.1 - 1.1e-26 93.3 0.0 3.1e-26 91.8 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EEQ69645.1 - 1.6e-13 51.0 0.6 3.4e-13 49.9 0.1 1.8 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EEQ69645.1 - 9.7e-07 28.2 0.1 2.3e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EEQ69645.1 - 0.0055 16.8 0.4 0.051 13.6 0.3 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 EEQ69646.1 - 4.3e-15 56.1 0.0 9e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EEQ69646.1 - 1.4e-05 24.4 0.2 4.4e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain PSDC PF12588.3 EEQ69646.1 - 0.11 12.1 0.1 0.32 10.5 0.0 1.7 2 0 0 2 2 2 0 Phophatidylserine decarboxylase PCI_Csn8 PF10075.4 EEQ69647.1 - 3.1e-46 156.6 0.0 4.2e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EEQ69647.1 - 2.2e-23 82.9 0.3 2.7e-23 82.6 0.2 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PDCD2_C PF04194.8 EEQ69648.1 - 1.6e-47 161.1 0.0 3.7e-47 159.9 0.0 1.6 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain A2L_zn_ribbon PF08792.5 EEQ69648.1 - 0.017 14.5 0.2 3.4 7.2 0.0 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain PAT1 PF09770.4 EEQ69648.1 - 2.3 6.3 14.6 2.7 6.1 10.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC27 PF09507.5 EEQ69648.1 - 7 5.7 10.0 9.2 5.3 6.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Folliculin PF11704.3 EEQ69650.1 - 5.7e-47 159.4 0.0 7.7e-47 158.9 0.0 1.2 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Clp1 PF06807.9 EEQ69652.1 - 7.6e-05 22.5 0.1 0.099 12.4 0.0 2.8 3 0 0 3 3 3 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EEQ69652.1 - 0.00094 18.9 0.0 0.0036 17.0 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EEQ69652.1 - 0.0018 17.7 0.0 0.0042 16.5 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_33 PF13671.1 EEQ69652.1 - 0.0056 16.5 0.2 0.03 14.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EEQ69652.1 - 0.11 13.3 0.0 0.3 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_polI_A34 PF08208.6 EEQ69653.1 - 2.5e-25 89.3 44.6 3.6e-24 85.5 18.4 3.2 2 1 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 SHMT PF00464.14 EEQ69654.1 - 5.1e-210 696.8 0.0 5.8e-210 696.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 EEQ69654.1 - 5.3e-07 28.9 0.0 1.2e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EEQ69654.1 - 0.00066 18.5 0.0 0.00096 17.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EEQ69654.1 - 0.0022 17.2 0.0 0.0033 16.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DUF3040 PF11239.3 EEQ69654.1 - 0.026 14.5 0.2 0.059 13.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Med9 PF07544.8 EEQ69655.1 - 9.9e-20 70.0 1.4 1.7e-19 69.3 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Metalloenzyme PF01676.13 EEQ69656.1 - 4e-75 252.4 0.0 4.6e-75 252.2 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 EEQ69656.1 - 1.9e-72 243.2 0.0 2.5e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 EEQ69656.1 - 1.7e-08 34.1 0.0 2.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EEQ69656.1 - 3.8e-06 26.3 0.0 1.1e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Sulfatase Alk_phosphatase PF00245.15 EEQ69656.1 - 0.002 16.9 0.1 0.028 13.1 0.0 2.1 2 0 0 2 2 2 1 Alkaline phosphatase PglZ PF08665.7 EEQ69656.1 - 0.05 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 PglZ domain Spt20 PF12090.3 EEQ69657.1 - 0.02 14.2 0.0 0.026 13.8 0.0 1.5 1 1 0 1 1 1 0 Spt20 family L31 PF09784.4 EEQ69657.1 - 0.13 12.3 0.3 0.2 11.7 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 AAA PF00004.24 EEQ69658.1 - 9.9e-41 139.0 0.0 1.8e-40 138.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EEQ69658.1 - 2.3e-29 101.0 0.2 7.3e-29 99.4 0.1 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EEQ69658.1 - 2.1e-22 78.7 2.0 2.1e-22 78.7 1.4 2.5 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EEQ69658.1 - 2.2e-07 31.6 0.3 1.9e-05 25.4 0.0 3.4 2 2 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EEQ69658.1 - 4.9e-06 26.7 0.1 0.00066 19.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EEQ69658.1 - 1.7e-05 23.8 0.0 0.00033 19.6 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 EEQ69658.1 - 2e-05 24.0 0.0 3.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EEQ69658.1 - 2.3e-05 24.2 0.0 6.7e-05 22.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EEQ69658.1 - 2.6e-05 23.3 0.0 4.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EEQ69658.1 - 2.6e-05 24.2 0.0 0.00038 20.4 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EEQ69658.1 - 2.8e-05 23.6 0.1 0.054 12.8 0.1 3.7 3 2 1 4 4 4 1 AAA domain RNA_helicase PF00910.17 EEQ69658.1 - 3.1e-05 24.1 0.0 0.0099 16.0 0.0 3.0 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.9 EEQ69658.1 - 5.6e-05 22.8 0.0 0.00016 21.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EEQ69658.1 - 9.8e-05 21.2 0.0 0.00016 20.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EEQ69658.1 - 0.00016 21.5 0.0 0.001 18.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EEQ69658.1 - 0.0013 18.6 0.0 0.011 15.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EEQ69658.1 - 0.0027 17.9 0.1 0.025 14.8 0.0 2.5 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 EEQ69658.1 - 0.0029 16.7 0.1 0.018 14.1 0.0 2.3 1 1 1 2 2 2 1 Zeta toxin Arch_ATPase PF01637.13 EEQ69658.1 - 0.0053 16.4 0.1 0.13 11.8 0.0 2.5 2 1 1 3 3 3 1 Archaeal ATPase AAA_24 PF13479.1 EEQ69658.1 - 0.0076 15.8 0.0 0.025 14.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain Parvo_NS1 PF01057.12 EEQ69658.1 - 0.0084 15.0 0.0 0.017 13.9 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Torsin PF06309.6 EEQ69658.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_19 PF13245.1 EEQ69658.1 - 0.012 15.3 0.0 0.04 13.6 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 EEQ69658.1 - 0.012 14.7 0.0 0.044 12.9 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EEQ69658.1 - 0.02 14.1 0.0 0.054 12.7 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EEQ69658.1 - 0.036 13.7 0.0 0.43 10.2 0.0 2.2 1 1 1 2 2 2 0 NACHT domain KaiC PF06745.8 EEQ69658.1 - 0.04 13.0 0.0 2.7 7.0 0.0 2.7 2 1 1 3 3 3 0 KaiC ResIII PF04851.10 EEQ69658.1 - 0.049 13.4 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit USP8_dimer PF08969.6 EEQ69658.1 - 0.062 13.2 1.8 0.15 12.0 1.3 1.7 1 0 0 1 1 1 0 USP8 dimerisation domain AAA_28 PF13521.1 EEQ69658.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EEQ69658.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 EEQ69658.1 - 0.11 11.9 0.0 0.31 10.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain CPT PF07931.7 EEQ69658.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.22 EEQ69658.1 - 0.12 12.6 0.1 0.72 10.1 0.0 2.5 2 1 0 2 2 2 0 ABC transporter TPR_1 PF00515.23 EEQ69658.1 - 0.48 10.1 3.9 0.33 10.6 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Microtub_assoc PF07989.6 EEQ69659.1 - 5.3e-27 93.4 6.6 5.3e-27 93.4 4.5 11.7 6 4 7 15 15 15 2 Microtubule associated PACT_coil_coil PF10495.4 EEQ69659.1 - 6e-25 86.9 0.2 1.9e-24 85.3 0.1 2.0 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein WEMBL PF05701.6 EEQ69659.1 - 0.00058 18.4 51.2 0.00058 18.4 35.5 6.0 1 1 6 7 7 7 5 Weak chloroplast movement under blue light SGT1 PF07093.6 EEQ69660.1 - 7.3e-142 473.7 26.4 1.2e-140 469.7 18.3 1.9 1 1 0 1 1 1 1 SGT1 protein AMMECR1 PF01871.12 EEQ69662.1 - 5.8e-40 136.2 0.0 2.1e-39 134.3 0.0 1.8 2 0 0 2 2 2 1 AMMECR1 Pkinase PF00069.20 EEQ69663.1 - 2.9e-63 213.4 0.0 2.1e-62 210.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ69663.1 - 5.5e-25 87.9 0.0 1.3e-24 86.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ69663.1 - 1.3e-06 27.6 0.0 2.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEQ69663.1 - 0.00028 20.7 0.2 0.00057 19.7 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ69663.1 - 0.001 18.1 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EEQ69663.1 - 0.052 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF1744 PF08490.7 EEQ69664.1 - 1.4e-150 501.2 0.0 2.1e-150 500.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EEQ69664.1 - 1.7e-67 227.6 2.6 6.1e-67 225.7 1.8 2.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EEQ69664.1 - 1.8e-20 73.2 0.0 1e-19 70.7 0.0 2.2 3 1 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EEQ69664.1 - 2.2e-10 40.4 0.1 5.9e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EEQ69664.1 - 5.4e-05 23.0 0.4 0.00047 20.0 0.0 2.6 2 0 0 2 2 2 1 RNase_H superfamily DUF3767 PF12597.3 EEQ69665.1 - 7.8e-37 125.5 0.0 1.6e-36 124.5 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3767) DUF3275 PF11679.3 EEQ69666.1 - 0.42 10.1 5.6 0.11 12.0 1.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) Nop PF01798.13 EEQ69667.1 - 9e-61 203.5 0.0 1.8e-60 202.6 0.0 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EEQ69667.1 - 2.7e-25 87.8 0.4 5.3e-25 86.9 0.3 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EEQ69667.1 - 2.9e-22 78.5 0.1 2.9e-22 78.5 0.1 2.8 3 1 0 3 3 3 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 EEQ69667.1 - 0.00053 19.7 23.0 0.001 18.8 16.0 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 RP-C_C PF11800.3 EEQ69667.1 - 9.5 5.8 8.5 88 2.6 5.2 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region Cpn60_TCP1 PF00118.19 EEQ69668.1 - 4.6e-149 497.1 0.1 5.2e-149 496.9 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MOZ_SAS PF01853.13 EEQ69669.1 - 2.1e-56 190.1 1.5 4.5e-52 176.0 0.1 2.1 2 0 0 2 2 2 2 MOZ/SAS family RRM_1 PF00076.17 EEQ69670.1 - 7.6e-12 44.6 0.0 1.5e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ69670.1 - 5.7e-05 23.0 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ69670.1 - 0.27 11.1 0.0 0.55 10.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA-synt_2 PF00152.15 EEQ69671.1 - 1.1e-57 195.3 0.0 4.7e-57 193.2 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EEQ69671.1 - 5.2e-07 29.4 0.0 8.3e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Gti1_Pac2 PF09729.4 EEQ69674.1 - 5.8e-50 169.4 0.7 1.1e-48 165.3 0.5 2.2 1 1 0 1 1 1 1 Gti1/Pac2 family DUF2434 PF10361.4 EEQ69675.1 - 4e-137 456.1 2.5 5.4e-137 455.7 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) MARVEL PF01284.18 EEQ69675.1 - 0.07 12.9 4.4 2.9 7.7 0.5 2.4 2 0 0 2 2 2 0 Membrane-associating domain DUF202 PF02656.10 EEQ69675.1 - 0.48 10.6 3.0 5.9 7.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Gp_dh_N PF00044.19 EEQ69676.1 - 0.0022 17.9 0.7 0.0026 17.7 0.5 1.0 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF3074 PF11274.3 EEQ69676.1 - 0.0058 16.2 2.0 0.0064 16.1 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) SHIPPO-rpt PF07004.7 EEQ69680.1 - 0.065 14.1 3.5 13 6.8 0.0 3.4 3 0 0 3 3 3 0 Sperm-tail PG-rich repeat Whib PF02467.11 EEQ69680.1 - 0.094 13.0 0.7 17 5.7 0.0 2.4 2 0 0 2 2 2 0 Transcription factor WhiB zf-RanBP PF00641.13 EEQ69680.1 - 0.12 11.4 3.6 4 6.6 0.3 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Zn_clus PF00172.13 EEQ69681.1 - 1.2e-07 31.4 9.6 2.6e-07 30.4 6.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cys_rich_VLP PF14194.1 EEQ69681.1 - 1.8 8.3 5.5 3.8 7.3 0.9 2.3 2 0 0 2 2 2 0 Cysteine-rich VLP zf-H2C2 PF09337.5 EEQ69681.1 - 3 7.3 10.2 1 8.8 1.3 3.0 3 0 0 3 3 3 0 His(2)-Cys(2) zinc finger F-box PF00646.28 EEQ69682.1 - 0.032 13.9 0.2 0.67 9.6 0.0 2.6 2 0 0 2 2 2 0 F-box domain CTP_transf_2 PF01467.21 EEQ69683.1 - 0.0024 17.9 0.6 0.046 13.7 0.2 2.4 2 1 0 2 2 2 1 Cytidylyltransferase WD40 PF00400.27 EEQ69684.1 - 1.7e-21 75.2 11.6 1.4e-07 31.1 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Acyl_transf_3 PF01757.17 EEQ69685.1 - 4.7e-33 114.4 42.0 4e-32 111.3 29.1 2.2 1 1 0 1 1 1 1 Acyltransferase family DUF996 PF06195.8 EEQ69685.1 - 0.6 10.0 5.3 0.29 11.1 1.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF996) mRNA_triPase PF02940.10 EEQ69686.1 - 1.6e-53 181.6 0.0 2.3e-53 181.1 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Kelch_3 PF13415.1 EEQ69687.1 - 5e-20 71.1 3.7 1.4e-11 44.1 0.0 5.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EEQ69687.1 - 1.3e-16 60.0 2.8 1.3e-07 31.2 0.0 5.9 5 2 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.10 EEQ69687.1 - 1.9e-11 43.2 0.0 4.2e-05 23.1 0.0 3.9 3 0 0 3 3 3 3 Kelch motif Kelch_5 PF13854.1 EEQ69687.1 - 3.3e-09 36.4 7.1 0.0012 18.7 0.7 5.0 3 2 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 EEQ69687.1 - 4.6e-09 35.6 0.2 0.0012 18.3 0.0 4.0 3 1 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 EEQ69687.1 - 4.6e-09 36.0 6.5 0.053 13.7 0.0 5.2 3 1 1 4 4 4 3 Kelch motif BTB PF00651.26 EEQ69687.1 - 0.0042 17.0 0.0 0.3 11.0 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain AhpC-TSA PF00578.16 EEQ69688.1 - 2.3e-32 111.2 0.0 3.5e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EEQ69688.1 - 6.8e-15 54.8 0.0 8.8e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EEQ69688.1 - 1.3e-11 43.9 0.1 2.2e-11 43.2 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin MFS_1 PF07690.11 EEQ69689.1 - 1.1e-44 152.6 27.7 1.1e-44 152.6 19.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEQ69689.1 - 5.1e-10 38.1 1.9 8.2e-10 37.5 1.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEQ69689.1 - 0.00039 19.1 11.5 0.00039 19.1 8.0 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter EVE PF01878.13 EEQ69690.1 - 7.5e-52 175.1 0.0 1.2e-51 174.5 0.0 1.3 1 0 0 1 1 1 1 EVE domain Methyltransf_PK PF05891.7 EEQ69691.1 - 1.6e-72 243.3 0.0 1.8e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 EEQ69691.1 - 7.8e-05 22.4 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ69691.1 - 0.0037 17.8 0.0 0.0065 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ69691.1 - 0.035 14.5 0.0 0.077 13.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Aldedh PF00171.17 EEQ69692.1 - 1.5e-181 603.7 1.7 1.7e-181 603.6 1.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EEQ69692.1 - 0.012 14.8 0.0 0.034 13.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DUF2188 PF09954.4 EEQ69692.1 - 0.13 12.2 0.8 0.39 10.6 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) DUF4209 PF13910.1 EEQ69696.1 - 0.11 12.5 0.5 0.19 11.7 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4209) DUF2344 PF10105.4 EEQ69696.1 - 0.12 11.8 1.9 0.13 11.7 1.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) DUF2856 PF11043.3 EEQ69696.1 - 0.31 11.1 3.9 0.23 11.5 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2856) DUF106 PF01956.11 EEQ69696.1 - 3.9 6.9 6.0 5 6.6 4.1 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 bZIP_2 PF07716.10 EEQ69698.1 - 7.4e-05 22.4 11.2 0.00013 21.7 7.7 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EEQ69698.1 - 0.1 12.8 6.8 0.22 11.8 4.7 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_1 PF00170.16 EEQ69698.1 - 2.1 8.3 10.5 4 7.4 7.3 1.4 1 0 0 1 1 1 0 bZIP transcription factor His_Phos_2 PF00328.17 EEQ69700.1 - 4e-54 184.2 0.0 4.7e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AT_hook PF02178.14 EEQ69701.1 - 4.4 7.3 10.1 0.068 12.8 1.3 2.7 2 0 0 2 2 2 0 AT hook motif Ribophorin_II PF05817.9 EEQ69703.1 - 2.7e-18 65.5 0.0 3.5e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Piwi PF02171.12 EEQ69705.1 - 5.5e-57 193.0 0.0 4.1e-46 157.3 0.0 2.3 2 0 0 2 2 2 2 Piwi domain DUF1785 PF08699.5 EEQ69705.1 - 5.8e-13 47.9 0.0 1.2e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EEQ69705.1 - 3.1e-10 39.4 0.2 1.8e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 PAZ domain adh_short_C2 PF13561.1 EEQ69706.1 - 4.3e-29 101.9 0.0 5.6e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEQ69706.1 - 2.3e-26 92.7 0.7 3.8e-26 91.9 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ69706.1 - 6.5e-15 55.2 0.3 1.2e-14 54.4 0.2 1.4 1 0 0 1 1 1 1 KR domain PLA2_B PF01735.13 EEQ69707.1 - 5.3e-197 654.8 0.1 6.2e-197 654.6 0.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain MgtE PF01769.11 EEQ69708.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Divalent cation transporter Aldose_epim PF01263.15 EEQ69709.1 - 7.7e-41 140.1 0.0 8.8e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Pox_C7_F8A PF03287.9 EEQ69709.1 - 0.0054 16.4 0.1 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Poxvirus C7/F8A protein Rif1_N PF12231.3 EEQ69710.1 - 1e-116 389.9 1.0 3.5e-110 368.4 0.0 2.6 1 1 1 2 2 2 2 Rap1-interacting factor 1 N terminal MFS_1 PF07690.11 EEQ69713.1 - 6.2e-25 87.6 27.2 6.2e-25 87.6 18.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF543 PF04418.7 EEQ69713.1 - 0.11 12.4 4.5 0.046 13.6 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Gly-zipper_OmpA PF13436.1 EEQ69714.1 - 5.3 6.7 9.7 8.5 6.0 6.7 1.4 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DAHP_synth_2 PF01474.11 EEQ69715.1 - 4.4e-194 644.8 0.0 5e-194 644.6 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family SOG2 PF10428.4 EEQ69716.1 - 0.00099 17.8 2.0 0.0011 17.7 1.4 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein MSP1_C PF07462.6 EEQ69716.1 - 0.19 10.0 1.8 0.22 9.8 1.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus LURAP PF14854.1 EEQ69716.1 - 1.7 8.3 4.8 0.41 10.3 0.9 1.6 1 1 1 2 2 2 0 Leucine rich adaptor protein Ribosomal_60s PF00428.14 EEQ69716.1 - 3.9 7.9 9.9 28 5.2 6.8 2.0 1 1 0 1 1 1 0 60s Acidic ribosomal protein Polysacc_synt_4 PF04669.8 EEQ69717.1 - 1.3e-23 83.4 1.2 9.8e-23 80.4 0.8 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis Tymo_45kd_70kd PF03251.8 EEQ69718.1 - 0.12 11.0 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Tymovirus 45/70Kd protein Ric8 PF10165.4 EEQ69719.1 - 2.3e-133 445.2 0.0 2.7e-133 445.0 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Sugar_tr PF00083.19 EEQ69721.1 - 4.4e-135 450.7 17.6 5e-135 450.5 12.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ69721.1 - 2e-26 92.5 36.5 7e-21 74.3 7.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_membrane PF00664.18 EEQ69724.1 - 1.2e-73 247.9 24.1 1.5e-41 142.6 6.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEQ69724.1 - 4.3e-59 198.7 0.0 3e-28 98.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EEQ69724.1 - 4.3e-17 62.0 1.7 8.3e-06 25.1 0.1 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EEQ69724.1 - 2.3e-09 36.6 1.7 0.0011 18.4 0.1 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EEQ69724.1 - 8.4e-09 36.2 0.3 0.0087 16.8 0.2 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EEQ69724.1 - 9.2e-09 35.5 1.1 0.00084 19.4 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EEQ69724.1 - 9.9e-09 35.4 0.3 0.0048 16.9 0.2 2.8 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 EEQ69724.1 - 1.4e-08 33.7 0.8 0.0029 16.2 0.0 3.8 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_10 PF12846.2 EEQ69724.1 - 2e-07 30.7 4.2 0.028 13.8 0.0 4.1 4 0 0 4 4 4 2 AAA-like domain AAA_21 PF13304.1 EEQ69724.1 - 2.2e-07 31.1 5.9 0.34 10.8 0.2 4.6 3 2 0 4 4 4 3 AAA domain AAA_18 PF13238.1 EEQ69724.1 - 1.8e-06 28.3 0.1 0.11 12.7 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEQ69724.1 - 2.8e-06 26.8 0.0 0.078 12.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EEQ69724.1 - 6.1e-06 25.5 0.0 0.069 12.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 EEQ69724.1 - 0.0002 21.2 0.0 0.85 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EEQ69724.1 - 0.0003 20.6 0.2 0.11 12.4 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EEQ69724.1 - 0.00048 20.5 0.5 0.044 14.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain DUF3987 PF13148.1 EEQ69724.1 - 0.0018 16.9 0.0 0.8 8.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) RNA_helicase PF00910.17 EEQ69724.1 - 0.0018 18.4 0.2 1.5 9.0 0.0 2.9 3 0 0 3 3 2 1 RNA helicase APS_kinase PF01583.15 EEQ69724.1 - 0.002 17.7 0.2 3 7.4 0.0 3.0 3 0 0 3 3 3 1 Adenylylsulphate kinase MMR_HSR1 PF01926.18 EEQ69724.1 - 0.0037 17.2 0.6 0.62 10.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 EEQ69724.1 - 0.005 16.5 0.5 2.3 7.9 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EEQ69724.1 - 0.0069 15.4 0.0 3.8 6.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 EEQ69724.1 - 0.0071 16.0 0.3 0.78 9.5 0.1 3.1 2 0 0 2 2 2 1 Part of AAA domain AAA PF00004.24 EEQ69724.1 - 0.008 16.3 0.8 7.1 6.8 0.0 3.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEQ69724.1 - 0.011 15.4 0.1 2.1 8.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EEQ69724.1 - 0.012 15.2 0.4 13 5.4 0.0 3.5 3 0 0 3 3 3 0 NACHT domain FtsK_SpoIIIE PF01580.13 EEQ69724.1 - 0.029 13.8 0.0 3.6 7.0 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family PhoH PF02562.11 EEQ69724.1 - 0.031 13.5 0.8 5.8 6.0 0.0 3.1 3 0 0 3 3 3 0 PhoH-like protein AAA_30 PF13604.1 EEQ69724.1 - 0.069 12.7 0.0 8.7 5.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 EEQ69724.1 - 0.077 12.7 1.7 8.9 6.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_13 PF13166.1 EEQ69724.1 - 0.08 11.3 1.2 1.5 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EEQ69724.1 - 0.083 12.0 0.0 1.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI T2SE PF00437.15 EEQ69724.1 - 0.092 11.6 0.1 6.8 5.5 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP_bind_1 PF03029.12 EEQ69724.1 - 0.1 12.1 0.3 12 5.3 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.17 EEQ69724.1 - 0.11 11.2 0.0 4.3 6.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.1 EEQ69724.1 - 0.17 11.4 0.1 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EEQ69724.1 - 0.22 10.6 5.4 5.7 5.9 0.0 3.4 4 0 0 4 4 4 0 KaiC PgaD PF13994.1 EEQ69725.1 - 0.049 13.1 2.0 4.1 6.8 0.4 2.3 2 0 0 2 2 2 0 PgaD-like protein APH PF01636.18 EEQ69727.1 - 9.7e-07 28.7 0.0 2.5e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family FA_hydroxylase PF04116.8 EEQ69728.1 - 3.5e-14 53.1 17.4 3.5e-14 53.1 12.1 2.7 2 2 0 2 2 2 1 Fatty acid hydroxylase superfamily Cep57_MT_bd PF06657.8 EEQ69729.1 - 7e-26 89.9 1.4 7e-26 89.9 0.9 3.4 3 0 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 EEQ69729.1 - 3.1e-21 75.0 9.7 3.1e-21 75.0 6.7 4.0 3 0 0 3 3 3 1 Centrosome localisation domain of PPC89 HALZ PF02183.13 EEQ69729.1 - 0.00042 19.9 3.0 0.00042 19.9 2.1 3.9 3 1 1 4 4 4 1 Homeobox associated leucine zipper DUF2205 PF10224.4 EEQ69729.1 - 0.0057 16.2 9.6 0.39 10.3 3.4 3.0 2 0 0 2 2 2 2 Predicted coiled-coil protein (DUF2205) MAT1 PF06391.8 EEQ69730.1 - 4.1e-35 121.1 14.9 5.3e-35 120.8 10.3 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 EEQ69730.1 - 0.00018 21.1 4.5 0.00068 19.2 3.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ69730.1 - 0.0034 17.0 6.2 0.0065 16.1 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ69730.1 - 0.0035 17.3 5.7 0.0082 16.1 4.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ69730.1 - 0.024 14.4 6.0 0.052 13.3 4.2 1.5 1 1 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 EEQ69730.1 - 0.024 14.3 8.9 0.33 10.7 6.6 2.2 1 1 1 2 2 2 0 zinc-RING finger domain DUF572 PF04502.8 EEQ69730.1 - 0.06 12.5 7.0 0.077 12.2 4.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) zf-RING_4 PF14570.1 EEQ69730.1 - 0.16 11.5 6.9 0.45 10.1 1.4 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prefoldin_3 PF13758.1 EEQ69731.1 - 1.2e-36 124.4 1.0 3.1e-36 123.1 0.7 1.7 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.2 EEQ69731.1 - 1.4e-23 83.6 14.6 6.8e-22 78.2 0.1 4.3 4 1 0 4 4 4 2 Domain of unknown function (DUF3835) Prefoldin PF02996.12 EEQ69731.1 - 0.012 15.2 1.3 0.04 13.5 0.9 1.9 1 1 0 1 1 1 0 Prefoldin subunit TMF_TATA_bd PF12325.3 EEQ69731.1 - 0.025 14.3 1.8 0.066 12.9 0.3 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding MerR-DNA-bind PF09278.6 EEQ69731.1 - 0.36 11.2 2.0 6.6 7.2 0.0 3.2 3 0 0 3 3 3 0 MerR, DNA binding DUF465 PF04325.8 EEQ69731.1 - 0.38 10.4 3.3 9.9 5.9 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Pox_A_type_inc PF04508.7 EEQ69731.1 - 0.46 10.3 4.0 19 5.3 0.1 3.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Pkinase PF00069.20 EEQ69732.1 - 2.4e-43 148.1 0.0 1.5e-42 145.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ69732.1 - 4.1e-26 91.6 0.0 6.9e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ69732.1 - 0.0039 16.9 0.8 0.023 14.4 0.1 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EEQ69732.1 - 0.0042 16.0 0.0 0.0095 14.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 EEQ69732.1 - 0.026 13.3 0.0 0.052 12.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EEQ69732.1 - 0.14 11.2 0.1 0.43 9.6 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family NGP1NT PF08153.7 EEQ69733.1 - 1.5e-48 164.0 0.1 2.3e-48 163.4 0.0 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EEQ69733.1 - 1.5e-19 70.0 0.0 8.1e-15 54.7 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EEQ69733.1 - 1.3e-05 24.5 0.0 0.00016 20.9 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EEQ69733.1 - 0.00044 20.1 0.1 0.31 10.8 0.0 3.4 2 1 1 3 3 3 1 Dynamin family Arf PF00025.16 EEQ69733.1 - 0.00063 19.0 0.0 0.1 11.8 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family DUF258 PF03193.11 EEQ69733.1 - 0.0028 16.8 0.0 0.0068 15.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EEQ69733.1 - 0.0055 16.1 0.0 1 8.7 0.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SusD-like_3 PF14322.1 EEQ69733.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Starch-binding associating with outer membrane Lactamase_B PF00753.22 EEQ69735.1 - 3.1e-06 26.9 0.4 4.4e-06 26.4 0.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily But2 PF09792.4 EEQ69736.1 - 1.1e-48 164.6 0.2 1.3e-48 164.3 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain PAP2 PF01569.16 EEQ69737.1 - 7.8e-20 70.8 0.6 1.6e-19 69.8 0.4 1.5 1 0 0 1 1 1 1 PAP2 superfamily DUF2763 PF10961.3 EEQ69738.1 - 0.022 15.1 0.1 0.022 15.1 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2763) MARVEL PF01284.18 EEQ69738.1 - 0.045 13.5 6.4 0.076 12.8 4.4 1.4 1 1 0 1 1 1 0 Membrane-associating domain DUF4018 PF13210.1 EEQ69738.1 - 0.19 11.0 5.9 0.29 10.4 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) BphX PF06139.7 EEQ69738.1 - 0.46 10.0 3.9 0.4 10.2 1.2 1.9 2 1 0 2 2 2 0 BphX-like SCAMP PF04144.8 EEQ69738.1 - 6 6.7 9.8 0.76 9.6 3.7 1.7 2 0 0 2 2 2 0 SCAMP family Aminotran_5 PF00266.14 EEQ69740.1 - 2.8e-23 82.2 0.0 5e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.11 EEQ69740.1 - 4.2e-23 81.3 0.0 1.3e-22 79.7 0.0 1.8 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EEQ69740.1 - 1.8e-19 69.5 0.0 6.4e-19 67.7 0.0 1.9 2 0 0 2 2 2 1 MOSC domain TPR_14 PF13428.1 EEQ69742.1 - 0.00019 21.7 1.9 8.9 7.2 0.0 6.0 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ69742.1 - 0.0013 18.9 0.0 1.3 9.3 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ69742.1 - 0.0043 17.6 0.8 3.9 8.2 0.1 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat DEAD PF00270.24 EEQ69743.1 - 2.1e-41 141.2 0.0 1.9e-40 138.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ69743.1 - 7.4e-26 89.8 0.3 1.8e-25 88.5 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF3334 PF11813.3 EEQ69743.1 - 0.051 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) ResIII PF04851.10 EEQ69743.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2986 PF11661.3 EEQ69743.1 - 0.51 10.7 9.1 0.043 14.1 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) Peptidase_M1 PF01433.15 EEQ69744.1 - 3.3e-143 477.4 1.0 5.3e-143 476.8 0.7 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EEQ69744.1 - 5.4e-91 305.2 0.8 7.4e-91 304.7 0.1 1.5 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EEQ69744.1 - 9.4e-20 70.9 0.3 1.8e-19 70.0 0.2 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2808 PF10989.3 EEQ69744.1 - 0.012 15.2 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) AA_permease_2 PF13520.1 EEQ69745.1 - 1.7e-93 313.4 34.7 1.7e-93 313.4 24.0 1.5 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 EEQ69745.1 - 3.8e-19 68.3 35.9 1e-18 66.9 24.9 1.6 1 1 0 1 1 1 1 Amino acid permease PsbN PF02468.10 EEQ69745.1 - 0.13 11.8 2.2 0.92 9.1 1.5 2.5 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) SP_C-Propep PF08999.5 EEQ69745.1 - 0.17 11.3 0.4 0.54 9.7 0.3 1.8 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide COesterase PF00135.23 EEQ69746.1 - 1.8e-05 23.6 0.0 0.00024 19.9 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family DUF3543 PF12063.3 EEQ69748.1 - 3.2e-95 317.8 0.0 5.8e-95 317.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 EEQ69748.1 - 1.3e-49 168.7 0.0 2.2e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ69748.1 - 7.4e-34 116.9 0.0 1.4e-33 116.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ69748.1 - 0.022 14.4 3.6 0.048 13.3 0.1 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family CTP_transf_1 PF01148.15 EEQ69751.1 - 1.8e-05 24.5 9.5 8.7e-05 22.3 1.6 3.5 3 1 0 3 3 3 2 Cytidylyltransferase family ATP_bind_4 PF01902.12 EEQ69752.1 - 6.9e-15 55.0 0.0 2e-05 24.0 0.0 3.8 4 0 0 4 4 4 3 ATP-binding region Ribonuc_L-PSP PF01042.16 EEQ69752.1 - 6.5e-14 51.7 0.0 6.8e-07 29.0 0.0 4.3 4 0 0 4 4 4 3 Endoribonuclease L-PSP zf-C2H2 PF00096.21 EEQ69753.1 - 1.2e-08 34.7 14.4 2.3e-06 27.6 1.2 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEQ69753.1 - 2.3e-06 27.5 13.8 2.4e-05 24.3 4.4 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEQ69753.1 - 5.7e-06 26.3 12.6 0.00034 20.7 3.7 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEQ69753.1 - 0.003 17.6 0.9 0.003 17.6 0.6 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEQ69753.1 - 0.0043 17.2 0.4 0.0043 17.2 0.3 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EEQ69753.1 - 0.0054 16.5 7.3 0.038 13.9 0.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger DUF4407 PF14362.1 EEQ69753.1 - 0.64 8.9 5.0 1 8.2 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YbgT_YccB PF08173.6 EEQ69754.1 - 0.46 10.3 5.3 0.87 9.4 3.7 1.5 1 0 0 1 1 1 0 Membrane bound YbgT-like protein PITH PF06201.8 EEQ69756.1 - 6.1e-39 133.2 0.0 1.3e-38 132.1 0.0 1.6 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EEQ69756.1 - 8.1e-28 96.1 0.0 1.7e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EEQ69756.1 - 3.6e-07 30.1 0.1 3.9e-06 26.8 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EEQ69756.1 - 2.7e-05 23.8 0.1 0.0015 18.2 0.0 2.3 1 1 1 2 2 2 2 AhpC/TSA family Thioredoxin_2 PF13098.1 EEQ69756.1 - 3e-05 24.2 0.1 0.00011 22.3 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EEQ69756.1 - 0.00014 21.8 0.0 0.00027 20.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EEQ69756.1 - 0.00036 20.0 0.1 0.31 10.5 0.0 2.3 1 1 1 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 EEQ69756.1 - 0.0087 15.6 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 EEQ69756.1 - 0.042 13.6 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EEQ69756.1 - 0.043 13.6 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain zf-CSL PF05207.8 EEQ69757.1 - 2.2e-14 52.7 0.2 5.1e-14 51.5 0.1 1.6 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EEQ69757.1 - 4.6e-11 42.2 0.3 2.7e-05 23.8 0.1 2.3 2 0 0 2 2 2 2 DnaJ domain peroxidase PF00141.18 EEQ69758.1 - 1.3e-51 175.3 0.0 2e-51 174.6 0.0 1.3 1 0 0 1 1 1 1 Peroxidase FMO-like PF00743.14 EEQ69762.1 - 0.15 10.2 0.0 0.22 9.6 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like LRR_2 PF07723.8 EEQ69764.1 - 0.14 12.6 1.1 5 7.7 0.1 3.1 3 0 0 3 3 3 0 Leucine Rich Repeat zf-C2H2_4 PF13894.1 EEQ69768.1 - 0.54 10.7 5.2 6 7.4 0.4 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger RasGEF PF00617.14 EEQ69770.1 - 3.6e-05 23.5 0.1 0.1 12.3 0.0 3.3 1 1 1 2 2 2 2 RasGEF domain HTH_12 PF08461.5 EEQ69770.1 - 0.14 11.9 0.9 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain bZIP_2 PF07716.10 EEQ69771.1 - 0.022 14.5 4.9 0.037 13.8 3.4 1.3 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.16 EEQ69771.1 - 0.26 11.2 6.2 0.49 10.3 4.3 1.4 1 0 0 1 1 1 0 bZIP transcription factor WD40 PF00400.27 EEQ69773.1 - 3.6e-24 83.6 8.4 6.1e-06 25.9 0.1 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat Glycos_transf_4 PF00953.16 EEQ69774.1 - 3.1e-33 114.8 12.6 3.1e-33 114.8 8.8 2.3 2 1 0 2 2 2 1 Glycosyl transferase family 4 Aconitase PF00330.15 EEQ69775.1 - 1.1e-182 607.6 0.0 1.4e-182 607.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EEQ69775.1 - 1.6e-42 144.7 0.0 4.1e-42 143.3 0.0 1.7 2 0 0 2 2 2 1 Aconitase C-terminal domain Alpha-amylase PF00128.19 EEQ69777.1 - 6.4e-17 61.9 1.7 2.3e-16 60.0 0.3 2.5 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EEQ69777.1 - 1.7e-13 50.6 0.1 3.2e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 EEQ69777.1 - 1.6e-06 28.3 0.0 3.8e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EEQ69777.1 - 2.9e-06 26.8 0.0 6.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 VGCC_beta4Aa_N PF12052.3 EEQ69777.1 - 0.27 11.1 0.1 0.73 9.7 0.1 1.6 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal DUF3723 PF12520.3 EEQ69778.1 - 1.4e-93 314.1 0.2 4e-92 309.3 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3723) DUF2313 PF10076.4 EEQ69780.1 - 0.035 13.4 0.3 0.042 13.2 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2313) Histone PF00125.19 EEQ69781.1 - 0.0017 18.4 0.2 0.0024 17.9 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Arylesterase PF01731.15 EEQ69782.1 - 1.6e-08 34.4 0.2 4.1e-08 33.0 0.1 1.8 2 0 0 2 2 2 1 Arylesterase SGL PF08450.7 EEQ69782.1 - 1.3e-06 27.9 0.0 1.5e-05 24.5 0.0 2.1 1 1 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Lactonase PF10282.4 EEQ69782.1 - 0.0016 17.5 0.0 0.036 13.1 0.0 2.4 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Ribosomal_L31 PF01197.13 EEQ69783.1 - 0.02 14.8 0.0 0.072 13.0 0.0 1.8 1 1 1 2 2 2 0 Ribosomal protein L31 MTHFR PF02219.12 EEQ69784.1 - 2.4e-115 384.5 0.0 3.8e-115 383.9 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF1804 PF08822.6 EEQ69784.1 - 0.027 14.2 0.1 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) DUF2418 PF10332.4 EEQ69786.1 - 6.4e-36 122.6 0.6 1.2e-35 121.8 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) ATP-synt_F PF01990.12 EEQ69787.1 - 5.4e-15 55.5 0.0 6.8e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit E1_DerP2_DerF2 PF02221.10 EEQ69789.1 - 8.1e-27 94.0 0.3 9.8e-27 93.8 0.2 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EEQ69789.1 - 0.00012 22.1 0.6 0.0006 19.8 0.4 1.9 1 1 0 1 1 1 1 ML-like domain NOGCT PF08155.6 EEQ69790.1 - 1.8e-29 101.2 1.7 3.5e-29 100.2 1.2 1.5 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 EEQ69790.1 - 6.4e-27 93.1 0.7 1.6e-26 91.9 0.5 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EEQ69790.1 - 1.4e-15 57.2 0.0 3e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEQ69790.1 - 6.7e-08 31.9 0.1 1.7e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EEQ69790.1 - 0.00023 21.6 0.0 0.00093 19.6 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EEQ69790.1 - 0.0027 17.5 0.0 2.9 7.6 0.0 2.7 1 1 1 2 2 2 2 Dynamin family Acetyltransf_1 PF00583.19 EEQ69791.1 - 1.2e-09 38.0 0.0 2.2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ69791.1 - 1.4e-08 34.7 0.0 2.2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ69791.1 - 0.0036 17.0 0.0 0.0081 15.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 EEQ69791.1 - 0.0072 16.2 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEQ69791.1 - 0.0092 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEQ69791.1 - 0.024 14.7 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Asp_protease PF09668.5 EEQ69792.1 - 4e-60 200.8 0.4 6.7e-60 200.1 0.3 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EEQ69792.1 - 3.3e-11 43.5 0.1 1.6e-10 41.3 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.18 EEQ69792.1 - 3.7e-09 35.8 0.0 6.8e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EEQ69792.1 - 1.8e-08 33.9 0.0 4.1e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain gag-asp_proteas PF13975.1 EEQ69792.1 - 1.1e-06 28.3 0.0 2.9e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EEQ69792.1 - 3.2e-05 23.8 0.0 6.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.3 EEQ69792.1 - 0.0002 20.9 0.1 0.00045 19.8 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.3 EEQ69792.1 - 0.00048 20.3 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 UBA_4 PF14555.1 EEQ69792.1 - 0.0028 17.1 0.0 0.0065 15.9 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain RVP PF00077.15 EEQ69792.1 - 0.0033 17.2 0.0 0.014 15.2 0.0 2.1 1 1 0 1 1 1 1 Retroviral aspartyl protease DUF2407 PF10302.4 EEQ69792.1 - 0.0083 16.2 0.2 0.018 15.2 0.1 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain MARVEL PF01284.18 EEQ69793.1 - 0.82 9.4 9.2 1.3 8.7 6.4 1.4 1 1 0 1 1 1 0 Membrane-associating domain Fungal_trans_2 PF11951.3 EEQ69794.1 - 8.7e-24 83.8 0.5 8.3e-18 64.1 0.3 3.2 3 0 0 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ69794.1 - 3.3e-07 30.0 12.9 5.4e-07 29.4 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEQ69794.1 - 0.0002 20.3 0.2 0.00048 19.0 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Apc5 PF12862.2 EEQ69794.1 - 0.062 13.1 0.1 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 Pkinase PF00069.20 EEQ69795.1 - 0.072 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Choline_kinase PF01633.15 EEQ69795.1 - 0.13 11.8 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Cu-oxidase_3 PF07732.10 EEQ69796.1 - 5.3e-41 139.0 0.3 1.1e-39 134.7 0.1 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EEQ69796.1 - 2.3e-26 91.9 3.1 7.8e-21 74.0 0.0 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EEQ69796.1 - 1.4e-18 67.2 0.0 5.6e-18 65.3 0.0 2.1 2 1 0 2 2 2 1 Multicopper oxidase AF0941-like PF14591.1 EEQ69797.1 - 0.0046 17.0 3.7 0.0078 16.2 2.5 1.5 1 1 0 1 1 1 1 AF0941-like Git3 PF11710.3 EEQ69799.1 - 3.2e-22 79.0 9.7 3.2e-22 79.0 6.7 2.5 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EEQ69799.1 - 2.2e-07 30.5 0.1 2.2e-07 30.5 0.1 2.8 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 EEQ69799.1 - 2.3e-07 30.2 9.6 3.4e-07 29.6 6.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 EEQ69799.1 - 0.0013 17.6 11.0 0.0016 17.4 7.3 1.4 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor CAF-1_p150 PF11600.3 EEQ69802.1 - 0.11 11.8 1.3 0.14 11.5 0.9 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Herpes_capsid PF06112.6 EEQ69802.1 - 2.6 8.1 10.1 3.5 7.6 7.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Methyltransf_23 PF13489.1 EEQ69804.1 - 1.4e-18 67.1 0.0 5.2e-18 65.2 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ69804.1 - 1.5e-05 24.6 0.0 0.00069 19.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ69804.1 - 0.00071 20.1 0.0 0.49 10.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ69804.1 - 0.0015 18.9 0.0 0.0043 17.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ69804.1 - 0.0038 16.3 0.0 7.5 5.5 0.0 3.0 2 1 1 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EEQ69804.1 - 0.012 15.9 0.0 0.29 11.5 0.0 2.5 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ69804.1 - 0.038 14.4 0.0 0.071 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 EEQ69805.1 - 3.5e-53 180.4 0.0 4.1e-50 170.4 0.0 3.0 3 1 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EEQ69805.1 - 1.9e-05 25.0 0.0 7.5e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EEQ69805.1 - 0.13 11.9 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Proteasome PF00227.21 EEQ69806.1 - 7.9e-56 188.3 0.1 1e-55 188.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEQ69806.1 - 8.6e-14 50.5 0.2 2.2e-13 49.2 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature ELH PF02323.10 EEQ69806.1 - 0.062 12.4 0.0 4.6 6.3 0.0 2.1 2 0 0 2 2 2 0 Egg-laying hormone precursor Spc97_Spc98 PF04130.8 EEQ69807.1 - 3.9e-136 454.5 0.4 6.2e-136 453.8 0.3 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family Thiolase_N PF00108.18 EEQ69808.1 - 1.4e-68 230.7 0.7 2.9e-68 229.7 0.5 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EEQ69808.1 - 1.4e-42 143.9 0.6 1.4e-42 143.9 0.4 2.2 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EEQ69808.1 - 0.00019 20.9 0.6 0.021 14.5 0.0 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 EEQ69808.1 - 0.0022 17.9 0.6 0.013 15.5 0.0 2.5 2 1 1 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AMP-binding PF00501.23 EEQ69809.1 - 1e-41 142.7 0.0 3.3e-20 71.8 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ69809.1 - 0.0091 16.9 0.0 0.026 15.4 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain KH_1 PF00013.24 EEQ69810.1 - 0.0025 17.4 0.2 0.016 14.8 0.0 2.2 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 EEQ69810.1 - 0.028 14.0 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 KH domain Methyltransf_23 PF13489.1 EEQ69811.1 - 7.2e-10 38.8 0.0 1.2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ69811.1 - 0.0011 19.4 0.0 0.03 14.8 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ69811.1 - 0.02 15.4 0.0 0.071 13.6 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ69811.1 - 0.066 13.6 0.0 0.4 11.1 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ69811.1 - 0.074 12.6 0.0 11 5.5 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase domain adh_short PF00106.20 EEQ69813.1 - 1.8e-18 67.0 0.0 2.6e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ69813.1 - 3.3e-10 40.1 0.0 4.6e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ69813.1 - 0.00017 21.2 0.0 0.00045 19.9 0.0 1.7 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EEQ69813.1 - 0.024 14.6 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EEQ69813.1 - 0.049 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EEQ69813.1 - 0.069 12.0 0.0 0.092 11.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ribosomal_L4 PF00573.17 EEQ69813.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family Erg28 PF03694.8 EEQ69814.1 - 8.4e-36 122.3 0.7 9.9e-36 122.1 0.5 1.0 1 0 0 1 1 1 1 Erg28 like protein GalP_UDP_transf PF01087.17 EEQ69815.1 - 9.5e-66 221.3 0.0 8.1e-65 218.3 0.0 2.2 2 1 1 3 3 3 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EEQ69815.1 - 2.6e-55 186.5 0.0 7.7e-55 184.9 0.0 1.7 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 EEQ69815.1 - 0.0017 18.8 0.0 0.17 12.4 0.0 2.7 2 1 0 2 2 2 1 HIT domain Herpes_UL37_1 PF03970.8 EEQ69815.1 - 0.042 12.6 0.0 0.078 11.7 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL37 tegument protein DcpS_C PF11969.3 EEQ69815.1 - 0.099 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Sua5_yciO_yrdC PF01300.13 EEQ69816.1 - 2.2e-11 43.3 0.0 3.1e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination F-box PF00646.28 EEQ69817.1 - 2.8e-05 23.6 1.8 6.1e-05 22.5 1.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EEQ69817.1 - 3.5e-05 23.4 2.2 7.6e-05 22.3 1.5 1.6 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EEQ69817.1 - 0.13 11.9 0.2 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 F-box-like domain NAD_binding_11 PF14833.1 EEQ69818.1 - 2.7e-06 27.4 0.0 4.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase BAR_2 PF10455.4 EEQ69820.1 - 1.9e-59 200.9 0.0 2.7e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EEQ69820.1 - 5.5e-20 71.8 0.7 1.2e-18 67.5 0.5 2.0 1 1 0 1 1 1 1 BAR domain zf-C4H2 PF10146.4 EEQ69820.1 - 0.063 13.2 2.3 0.12 12.3 0.1 2.1 2 1 1 3 3 3 0 Zinc finger-containing protein Binary_toxB PF03495.9 EEQ69821.1 - 0.019 13.5 0.1 0.026 13.1 0.0 1.1 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA ATP_synt_H PF05493.8 EEQ69823.1 - 1.6e-26 92.1 1.8 1.8e-26 91.9 1.3 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF1129 PF06570.6 EEQ69823.1 - 0.0039 16.5 0.4 0.0047 16.2 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) AmiS_UreI PF02293.10 EEQ69823.1 - 0.051 13.2 0.1 0.06 12.9 0.1 1.0 1 0 0 1 1 1 0 AmiS/UreI family transporter DUF2142 PF09913.4 EEQ69823.1 - 0.051 12.2 0.2 0.059 12.0 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) DUF4131 PF13567.1 EEQ69823.1 - 0.072 12.4 1.9 0.077 12.4 1.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Claudin_2 PF13903.1 EEQ69823.1 - 0.14 11.7 2.1 0.17 11.5 1.4 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction ABC2_membrane_2 PF12679.2 EEQ69823.1 - 0.17 10.6 1.5 0.2 10.4 1.0 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Arv1 PF04161.8 EEQ69824.1 - 6.2e-40 137.3 0.1 6.4e-35 120.9 0.0 2.3 2 0 0 2 2 2 2 Arv1-like family DUF619 PF04768.8 EEQ69825.1 - 1.1e-49 168.1 0.0 3.5e-49 166.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Nucleoporin_C PF03177.9 EEQ69827.1 - 5.6e-139 464.3 3.0 7e-139 464.0 2.1 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EEQ69827.1 - 7.3e-89 298.4 0.1 9.5e-89 298.0 0.1 1.1 1 0 0 1 1 1 1 Nup133 N terminal like SUI1 PF01253.17 EEQ69827.1 - 0.23 11.2 0.1 8 6.3 0.0 2.6 2 0 0 2 2 2 0 Translation initiation factor SUI1 YqeY PF09424.5 EEQ69828.1 - 4.3e-21 75.2 2.4 4.7e-21 75.1 1.6 1.1 1 0 0 1 1 1 1 Yqey-like protein GTP_EFTU_D4 PF14578.1 EEQ69828.1 - 0.035 13.7 0.6 0.075 12.6 0.4 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 4 CM_2 PF01817.16 EEQ69828.1 - 0.073 13.1 1.2 0.15 12.1 0.8 1.5 1 0 0 1 1 1 0 Chorismate mutase type II L27_1 PF09058.5 EEQ69828.1 - 0.11 12.4 0.2 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 L27_1 Rot1 PF10681.4 EEQ69829.1 - 3e-82 275.1 0.3 9e-82 273.5 0.2 1.6 1 1 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal 5-FTHF_cyc-lig PF01812.15 EEQ69830.1 - 3e-33 115.1 0.1 9.1e-33 113.5 0.1 1.7 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family LSM PF01423.17 EEQ69831.1 - 1.1e-14 53.7 0.2 1.3e-14 53.4 0.2 1.1 1 0 0 1 1 1 1 LSM domain PP1_inhibitor PF05361.7 EEQ69831.1 - 0.094 12.3 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor PhnA PF03831.9 EEQ69831.1 - 0.1 12.0 0.0 0.46 9.9 0.0 2.0 2 0 0 2 2 2 0 PhnA protein Xpo1 PF08389.7 EEQ69832.1 - 3.8e-26 91.7 0.6 2.9e-25 88.9 0.1 2.8 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EEQ69832.1 - 2.5e-07 30.5 0.2 6.1e-06 26.0 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EEQ69832.1 - 0.002 18.3 0.2 0.042 14.1 0.0 3.2 3 1 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.1 EEQ69832.1 - 0.0033 17.8 0.7 0.33 11.5 0.0 4.7 5 0 0 5 5 5 1 HEAT-like repeat Adaptin_N PF01602.15 EEQ69832.1 - 0.012 13.9 0.1 1.7 6.8 0.1 2.3 2 0 0 2 2 2 0 Adaptin N terminal region HEAT PF02985.17 EEQ69832.1 - 0.013 15.5 0.0 6.9 7.0 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat Fungal_trans PF04082.13 EEQ69833.1 - 1.7e-63 213.9 0.2 2.6e-63 213.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EEQ69833.1 - 5.1e-05 23.3 14.2 0.0017 18.5 2.2 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ69833.1 - 0.0032 17.6 2.4 0.0032 17.6 1.7 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EEQ69833.1 - 0.037 14.3 11.6 0.82 10.0 2.9 2.8 2 0 0 2 2 2 0 Zinc-finger double domain ACT_3 PF10000.4 EEQ69834.1 - 6e-21 73.9 0.1 1.2e-20 72.9 0.1 1.5 2 0 0 2 2 2 1 ACT domain ACT_7 PF13840.1 EEQ69834.1 - 3.4e-12 45.7 0.0 4.5e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 ACT domain EF-hand_7 PF13499.1 EEQ69835.1 - 2.4e-14 53.2 0.1 7e-10 38.9 0.1 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EEQ69835.1 - 9.8e-12 43.7 0.2 0.00086 19.0 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.27 EEQ69835.1 - 4.4e-10 38.1 0.1 0.015 14.5 0.0 3.8 3 1 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 EEQ69835.1 - 1.7e-08 34.2 0.0 0.00084 19.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EEQ69835.1 - 2.2e-06 27.1 0.6 0.00095 18.7 0.1 3.4 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 EEQ69835.1 - 0.064 12.6 2.5 2.4 7.6 0.7 3.3 3 0 0 3 3 3 0 EF hand Bclt PF15318.1 EEQ69836.1 - 0.46 10.4 7.6 0.37 10.7 0.1 2.2 2 0 0 2 2 2 0 Putative Bcl-2 like protein of testis CDC45 PF02724.9 EEQ69836.1 - 3 5.7 9.2 2.9 5.8 3.3 2.0 2 0 0 2 2 2 0 CDC45-like protein Glypican PF01153.14 EEQ69836.1 - 4.7 5.6 6.7 2.4 6.6 0.2 2.2 2 0 0 2 2 2 0 Glypican Spt5_N PF11942.3 EEQ69836.1 - 5.4 7.7 16.9 0.6 10.7 4.6 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Peptidase_M3 PF01432.15 EEQ69837.1 - 6.2e-160 533.1 0.1 1e-159 532.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M3 Xan_ur_permease PF00860.15 EEQ69838.1 - 3.8e-56 190.2 28.9 4.1e-42 144.0 10.3 3.0 1 1 1 2 2 2 2 Permease family TspO_MBR PF03073.10 EEQ69838.1 - 0.04 13.4 4.0 0.12 11.8 2.7 1.8 1 0 0 1 1 1 0 TspO/MBR family FA_desaturase PF00487.19 EEQ69839.1 - 6.1e-18 65.2 13.7 6.1e-18 65.2 9.5 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EEQ69839.1 - 4.4e-17 61.6 0.1 1.2e-16 60.3 0.1 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain p450 PF00067.17 EEQ69840.1 - 8.3e-39 133.3 0.0 1.1e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AKAP_110 PF05716.8 EEQ69840.1 - 0.15 10.0 0.0 0.19 9.6 0.0 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 110 kDa (AKAP 110) AAA_25 PF13481.1 EEQ69842.1 - 2.4e-06 27.0 0.0 0.00067 19.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain Rad51 PF08423.6 EEQ69842.1 - 0.00019 20.4 0.0 0.012 14.5 0.0 3.2 1 1 0 1 1 1 1 Rad51 DnaB_C PF03796.10 EEQ69842.1 - 0.0011 17.9 0.2 0.43 9.4 0.0 2.3 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain KaiC PF06745.8 EEQ69842.1 - 0.0018 17.4 0.1 0.025 13.7 0.0 2.5 3 0 0 3 3 3 1 KaiC IstB_IS21 PF01695.12 EEQ69842.1 - 0.0026 17.2 0.2 0.0044 16.4 0.1 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 EEQ69842.1 - 0.0067 17.2 0.0 0.92 10.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 EEQ69842.1 - 0.0071 15.5 0.1 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_16 PF13191.1 EEQ69842.1 - 0.01 15.8 0.0 0.021 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 EEQ69842.1 - 0.016 15.3 0.1 0.17 12.0 0.0 2.5 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EEQ69842.1 - 0.035 13.8 0.5 0.079 12.7 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 EEQ69842.1 - 0.053 13.2 0.0 0.29 10.7 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase RuvB_N PF05496.7 EEQ69842.1 - 0.054 12.5 0.3 6.2 5.7 0.0 2.7 3 0 0 3 3 3 0 Holliday junction DNA helicase ruvB N-terminus ABC_tran PF00005.22 EEQ69842.1 - 0.056 13.7 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 EEQ69842.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RecA PF00154.16 EEQ69842.1 - 0.13 11.2 0.8 0.2 10.6 0.0 1.5 2 0 0 2 2 2 0 recA bacterial DNA recombination protein AAA_22 PF13401.1 EEQ69842.1 - 0.13 12.3 0.0 0.43 10.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain Zn_clus PF00172.13 EEQ69843.1 - 3e-10 39.8 8.5 5.2e-10 39.0 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FerA PF08165.6 EEQ69843.1 - 0.1 12.3 0.3 0.23 11.1 0.2 1.6 1 1 1 2 2 2 0 FerA (NUC095) domain TMF_DNA_bd PF12329.3 EEQ69843.1 - 0.13 12.0 0.6 0.22 11.3 0.4 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.7 EEQ69843.1 - 0.14 12.4 0.2 0.22 11.7 0.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein XhlA PF10779.4 EEQ69843.1 - 0.2 11.5 0.3 0.3 11.0 0.2 1.2 1 0 0 1 1 1 0 Haemolysin XhlA MOSC PF03473.12 EEQ69844.1 - 1.2e-10 40.9 0.1 6.7e-07 28.8 0.0 2.3 2 0 0 2 2 2 2 MOSC domain MOSC_N PF03476.11 EEQ69844.1 - 6.6e-07 29.0 0.0 1.3e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain SAP30_Sin3_bdg PF13867.1 EEQ69845.1 - 9.1e-17 60.6 0.0 1.6e-15 56.6 0.0 2.4 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Ashwin PF15323.1 EEQ69845.1 - 1.7 8.5 11.5 0.24 11.3 2.3 2.0 1 1 0 2 2 2 0 Developmental protein zf-H2C2_2 PF13465.1 EEQ69847.1 - 8.3e-08 32.1 25.8 6.9e-06 26.1 2.9 4.9 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 EEQ69847.1 - 0.00016 21.8 15.2 0.0024 18.1 2.8 4.1 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ69847.1 - 0.0033 17.6 1.2 0.0033 17.6 0.8 4.8 5 1 1 6 6 6 2 C2H2-type zinc finger BRO1 PF03097.13 EEQ69848.1 - 1.8e-129 431.7 0.9 1.8e-129 431.7 0.6 2.2 2 1 1 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EEQ69848.1 - 6.8e-99 330.5 13.5 6.8e-99 330.5 9.4 1.7 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Reo_sigmaC PF04582.7 EEQ69848.1 - 0.17 10.9 2.6 0.2 10.8 0.3 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein CTDII PF01556.13 EEQ69849.1 - 2.9e-31 107.1 2.8 2.1e-22 78.8 0.2 3.3 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ PF00226.26 EEQ69849.1 - 1.6e-23 82.1 2.2 3.5e-23 81.1 1.5 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EEQ69849.1 - 8.8e-11 41.7 21.8 2.3e-10 40.3 15.1 1.8 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EEQ69849.1 - 0.45 10.2 9.4 1.3 8.7 1.3 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Lon_C PF05362.8 EEQ69850.1 - 3.3e-62 209.4 0.0 6.7e-62 208.4 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EEQ69850.1 - 9.1e-41 139.7 1.4 1.3e-40 139.3 0.1 1.9 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EEQ69850.1 - 5.3e-22 78.4 0.0 1.4e-21 77.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEQ69850.1 - 2.3e-07 30.5 0.0 5.5e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EEQ69850.1 - 2.3e-06 27.6 0.0 7e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EEQ69850.1 - 2.2e-05 24.6 0.1 0.00039 20.5 0.0 2.6 1 1 0 1 1 1 1 AAA domain ChlI PF13541.1 EEQ69850.1 - 2.5e-05 23.7 0.0 6.5e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 EEQ69850.1 - 5e-05 23.3 0.1 0.0013 18.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_PrkA PF08298.6 EEQ69850.1 - 5e-05 22.1 0.0 0.00012 20.9 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain AAA_17 PF13207.1 EEQ69850.1 - 7.7e-05 23.4 0.1 0.00044 21.0 0.0 2.4 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EEQ69850.1 - 0.00026 20.1 0.0 0.0016 17.5 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EEQ69850.1 - 0.0099 16.1 4.4 0.031 14.6 0.0 3.6 4 0 0 4 4 3 1 AAA domain SKI PF01202.17 EEQ69850.1 - 0.012 15.4 0.2 0.13 12.0 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase AAA_14 PF13173.1 EEQ69850.1 - 0.013 15.4 0.0 0.032 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EEQ69850.1 - 0.032 13.6 0.0 0.37 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 EEQ69850.1 - 0.037 14.2 0.0 0.19 11.8 0.0 2.3 2 0 0 2 2 1 0 RNA helicase DUF258 PF03193.11 EEQ69850.1 - 0.039 13.1 0.0 0.1 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 EEQ69850.1 - 0.04 13.6 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EEQ69850.1 - 0.051 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATP-synt_ab PF00006.20 EEQ69850.1 - 0.069 12.6 0.0 0.19 11.2 0.0 1.8 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 EEQ69850.1 - 0.072 12.4 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EEQ69850.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EEQ69850.1 - 0.61 10.3 3.8 0.8 10.0 0.0 2.8 3 0 0 3 3 3 0 ABC transporter Pkinase PF00069.20 EEQ69852.1 - 5.7e-12 45.3 0.1 1.3e-10 40.9 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ69852.1 - 2e-10 40.1 0.0 1.5e-09 37.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEQ69852.1 - 0.14 11.2 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mob1_phocein PF03637.12 EEQ69854.1 - 1.4e-25 90.0 0.1 2.3e-25 89.2 0.1 1.3 1 0 0 1 1 1 1 Mob1/phocein family cobW PF02492.14 EEQ69855.1 - 3.6e-28 98.1 0.1 5e-28 97.7 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EEQ69855.1 - 3.1e-07 30.0 0.0 1.3e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain HAUS6_N PF14661.1 EEQ69856.1 - 3.9e-59 200.0 0.8 1.4e-58 198.2 0.1 1.9 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus Peptidase_M1 PF01433.15 EEQ69856.1 - 0.098 11.7 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Peptidase family M1 HD_3 PF13023.1 EEQ69857.1 - 4e-47 160.0 0.1 4.8e-47 159.7 0.1 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EEQ69857.1 - 0.022 14.7 0.1 0.045 13.7 0.1 1.5 1 1 0 1 1 1 0 HD domain HD_2 PF12917.2 EEQ69857.1 - 0.05 13.3 0.0 0.063 13.0 0.0 1.1 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme HIT PF01230.18 EEQ69858.1 - 4.1e-25 88.1 0.2 8.2e-25 87.2 0.0 1.6 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EEQ69858.1 - 2.8e-05 24.3 0.0 4.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding MCR_D PF02505.9 EEQ69858.1 - 0.1 12.1 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein D Rad4 PF03835.10 EEQ69859.1 - 3.6e-32 110.7 0.3 1.1e-31 109.1 0.0 2.0 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EEQ69859.1 - 2e-28 97.9 0.1 4.5e-28 96.7 0.1 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.4 EEQ69859.1 - 1.8e-18 66.5 1.7 3.2e-18 65.7 0.1 2.3 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.4 EEQ69859.1 - 7.4e-18 63.8 0.1 1.5e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.14 EEQ69859.1 - 0.0048 17.0 0.0 0.016 15.4 0.0 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily Sigma70_ner PF04546.8 EEQ69859.1 - 0.29 10.7 10.9 0.062 12.9 4.7 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region CDC45 PF02724.9 EEQ69859.1 - 0.66 7.9 3.5 1 7.3 2.4 1.3 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 EEQ69859.1 - 0.92 8.6 10.0 1.8 7.7 6.9 1.4 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 EEQ69859.1 - 3.5 7.1 13.4 9.8 5.6 9.3 1.7 1 0 0 1 1 1 0 Nucleoplasmin Sporozoite_P67 PF05642.6 EEQ69859.1 - 7.1 4.3 8.5 12 3.5 5.9 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CoA_binding_2 PF13380.1 EEQ69860.1 - 1.2e-27 96.4 0.0 1.4e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Pkinase PF00069.20 EEQ69861.1 - 6.8e-31 107.3 0.0 1.2e-30 106.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ69861.1 - 1.4e-07 30.8 0.0 1.6e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase MutS_III PF05192.13 EEQ69862.1 - 0.13 12.0 0.4 0.24 11.1 0.3 1.4 1 0 0 1 1 1 0 MutS domain III SRCR PF00530.13 EEQ69865.1 - 0.079 13.3 0.3 0.22 11.8 0.1 1.8 1 1 1 2 2 2 0 Scavenger receptor cysteine-rich domain eIF-4B PF06273.6 EEQ69867.1 - 0.14 10.9 0.2 0.15 10.7 0.1 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Fungal_trans PF04082.13 EEQ69869.1 - 5.2e-32 110.7 0.9 1e-31 109.8 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ69869.1 - 0.00019 21.2 2.5 0.00036 20.3 1.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SelP_N PF04592.9 EEQ69869.1 - 0.68 9.2 10.4 1.8 7.9 7.2 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 EEQ69869.1 - 1.3 8.0 4.4 2.8 6.8 3.0 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter ABC2_membrane PF01061.19 EEQ69870.1 - 5e-66 221.8 38.1 4.1e-43 147.0 11.9 3.0 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 EEQ69870.1 - 1.8e-35 122.2 0.0 1e-17 64.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EEQ69870.1 - 1.2e-27 95.5 2.5 7.7e-25 86.5 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter AAA_25 PF13481.1 EEQ69870.1 - 1.2e-05 24.8 0.1 0.0069 15.8 0.1 2.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EEQ69870.1 - 2.2e-05 23.7 1.4 0.00069 18.8 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EEQ69870.1 - 2.4e-05 24.3 0.5 0.0013 18.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EEQ69870.1 - 5.7e-05 23.0 0.0 0.0056 16.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EEQ69870.1 - 0.00012 22.2 0.0 0.15 12.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EEQ69870.1 - 0.00022 20.7 1.2 0.018 14.5 0.4 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EEQ69870.1 - 0.00022 21.1 0.0 0.079 12.9 0.0 3.0 3 0 0 3 3 3 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EEQ69870.1 - 0.00056 19.4 0.0 0.13 11.6 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_21 PF13304.1 EEQ69870.1 - 0.00074 19.5 0.0 0.31 10.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EEQ69870.1 - 0.013 14.9 0.9 1.8 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain cobW PF02492.14 EEQ69870.1 - 0.023 14.1 2.4 0.087 12.2 0.5 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EEQ69870.1 - 0.026 14.1 0.2 1.9 8.1 0.2 2.5 2 0 0 2 2 2 0 NACHT domain Miro PF08477.8 EEQ69870.1 - 0.037 14.5 0.0 0.61 10.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_30 PF13604.1 EEQ69870.1 - 0.042 13.4 0.4 4.1 6.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 EEQ69870.1 - 0.088 11.8 0.0 0.3 10.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 EEQ69870.1 - 0.1 12.9 0.0 0.79 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EEQ69870.1 - 0.15 11.6 0.4 20 4.8 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 EEQ69870.1 - 0.24 10.4 0.5 1.2 8.2 0.1 2.1 2 0 0 2 2 2 0 Zeta toxin PRK PF00485.13 EEQ69870.1 - 0.39 10.2 1.9 0.71 9.3 0.0 2.4 4 0 0 4 4 3 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.1 EEQ69870.1 - 0.68 10.2 3.1 1.9 8.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain Fungal_trans_2 PF11951.3 EEQ69871.1 - 1.8e-40 138.7 9.9 1.1e-39 136.1 6.8 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ69871.1 - 6e-06 26.0 9.8 1.7e-05 24.6 6.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EEQ69872.1 - 4e-32 111.3 16.1 5e-32 110.9 11.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily AMP-binding PF00501.23 EEQ69873.1 - 2.1e-67 227.3 0.4 9.4e-67 225.1 0.3 1.8 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ69873.1 - 2.5e-09 37.9 0.7 7e-09 36.5 0.2 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF3735 PF12537.3 EEQ69873.1 - 0.049 13.6 0.6 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3735) Pol_alpha_B_N PF08418.5 EEQ69874.1 - 1.6 8.1 18.2 2.7 7.4 12.6 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF605 PF04652.11 EEQ69874.1 - 2.7 7.2 13.7 3.8 6.8 9.5 1.1 1 0 0 1 1 1 0 Vta1 like CytochromB561_N PF09786.4 EEQ69874.1 - 3.1 6.1 15.2 4.4 5.6 10.5 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Sugar_tr PF00083.19 EEQ69875.1 - 2.2e-19 69.3 25.0 3.5e-17 62.1 17.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Ferritin_2 PF13668.1 EEQ69876.1 - 9.2e-11 41.8 0.0 1.3e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain CD24 PF14984.1 EEQ69876.1 - 0.039 13.7 1.3 0.039 13.7 0.9 3.0 3 0 0 3 3 3 0 CD24 protein ABC_membrane PF00664.18 EEQ69878.1 - 1.8e-80 270.2 26.5 9e-43 146.6 11.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEQ69878.1 - 2.7e-66 222.0 0.0 4.8e-34 117.5 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EEQ69878.1 - 7.3e-19 67.8 0.2 1.8e-05 24.1 0.0 4.4 3 1 1 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEQ69878.1 - 3e-15 56.9 0.0 0.00011 22.3 0.0 4.1 2 2 1 3 3 3 3 AAA domain DUF258 PF03193.11 EEQ69878.1 - 7.9e-10 38.1 0.0 0.00095 18.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEQ69878.1 - 5.6e-09 36.2 0.9 0.0045 17.1 0.0 4.2 4 1 0 4 4 3 2 AAA domain AAA_29 PF13555.1 EEQ69878.1 - 9.9e-09 34.6 0.5 0.0012 18.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EEQ69878.1 - 5.8e-08 32.9 0.1 0.01 15.8 0.0 3.3 3 1 0 3 3 3 2 AAA ATPase domain ABC_ATPase PF09818.4 EEQ69878.1 - 1.1e-07 30.7 0.0 0.0078 14.8 0.0 3.4 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 EEQ69878.1 - 2.2e-07 31.7 0.0 0.036 14.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.10 EEQ69878.1 - 4.8e-07 28.8 0.0 0.024 13.3 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA PF00004.24 EEQ69878.1 - 2.1e-06 27.9 1.5 0.23 11.6 0.1 4.6 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EEQ69878.1 - 7e-06 25.5 0.3 0.1 11.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EEQ69878.1 - 7e-06 26.4 0.6 0.012 16.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EEQ69878.1 - 2.7e-05 23.8 0.1 0.41 10.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EEQ69878.1 - 9.3e-05 22.3 0.0 0.97 9.3 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_30 PF13604.1 EEQ69878.1 - 0.00022 20.8 0.2 0.15 11.6 0.0 3.5 3 1 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EEQ69878.1 - 0.0005 19.9 0.0 1.5 8.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 EEQ69878.1 - 0.00051 20.3 0.0 1.8 8.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EEQ69878.1 - 0.00058 19.7 0.5 0.35 10.7 0.1 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 EEQ69878.1 - 0.0014 18.8 0.0 3.6 7.8 0.0 3.2 3 0 0 3 3 2 1 RNA helicase AAA_15 PF13175.1 EEQ69878.1 - 0.0019 17.3 0.1 0.99 8.3 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain NB-ARC PF00931.17 EEQ69878.1 - 0.0031 16.3 0.0 0.54 9.0 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_28 PF13521.1 EEQ69878.1 - 0.0034 17.3 0.2 3.3 7.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 EEQ69878.1 - 0.0037 16.8 0.0 3.1 7.3 0.0 2.4 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 EEQ69878.1 - 0.004 16.2 0.0 0.26 10.3 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.12 EEQ69878.1 - 0.0059 16.0 0.4 1.7 8.0 0.0 3.3 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_19 PF13245.1 EEQ69878.1 - 0.008 15.9 0.8 1.2 8.9 0.0 3.2 4 0 0 4 4 2 1 Part of AAA domain ATP-synt_ab PF00006.20 EEQ69878.1 - 0.0097 15.4 3.0 0.42 10.0 0.1 3.1 3 1 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain SRP54 PF00448.17 EEQ69878.1 - 0.012 15.0 0.0 5.4 6.4 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 EEQ69878.1 - 0.014 14.8 0.0 6 6.2 0.0 2.8 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 EEQ69878.1 - 0.02 14.8 0.0 9.9 6.1 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase MobB PF03205.9 EEQ69878.1 - 0.03 14.0 0.6 14 5.3 0.0 3.3 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_PrkA PF08298.6 EEQ69878.1 - 0.059 12.0 0.0 4.8 5.7 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain DUF3987 PF13148.1 EEQ69878.1 - 0.1 11.1 0.0 11 4.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) tRNA_lig_kinase PF08303.6 EEQ69878.1 - 0.11 12.3 0.1 67 3.2 0.0 3.4 3 0 0 3 3 3 0 tRNA ligase kinase domain Cu_amine_oxid PF01179.15 EEQ69879.1 - 2.9e-171 569.7 0.1 3.4e-171 569.5 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EEQ69879.1 - 0.0003 20.7 0.0 0.00068 19.6 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain UQ_con PF00179.21 EEQ69882.1 - 2.6e-39 133.8 0.0 2.9e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEQ69882.1 - 0.0044 16.7 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEQ69882.1 - 0.0082 16.0 0.5 0.011 15.6 0.3 1.5 1 1 0 1 1 1 1 RWD domain UFC1 PF08694.6 EEQ69882.1 - 0.13 11.7 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 HhH-GPD PF00730.20 EEQ69883.1 - 4.9e-19 68.6 0.1 1.1e-17 64.2 0.0 2.6 3 0 0 3 3 3 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EEQ69883.1 - 1e-06 28.0 0.0 2.5e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF927 PF06048.6 EEQ69883.1 - 0.021 14.0 0.7 0.038 13.2 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF927) DUF2259 PF10016.4 EEQ69883.1 - 0.071 12.8 0.3 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 Predicted secreted protein (DUF2259) AAA_11 PF13086.1 EEQ69884.1 - 1.6e-61 207.9 0.9 2.6e-61 207.2 0.2 1.7 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EEQ69884.1 - 1.6e-55 187.6 0.0 3e-55 186.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ69884.1 - 6.5e-14 51.4 0.1 2.8e-12 46.1 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EEQ69884.1 - 1.3e-11 44.4 0.0 1.2e-09 38.0 0.0 2.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EEQ69884.1 - 2.2e-07 30.9 0.0 8e-07 29.0 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EEQ69884.1 - 3.4e-07 30.0 0.0 0.21 11.0 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EEQ69884.1 - 6.1e-07 28.7 0.2 4.4e-06 25.8 0.1 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 EEQ69884.1 - 7.2e-06 25.5 0.2 3.7e-05 23.1 0.1 2.3 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 EEQ69884.1 - 1.4e-05 25.2 0.1 0.0012 19.0 0.1 2.6 1 1 0 1 1 1 1 AAA domain UvrD_C PF13361.1 EEQ69884.1 - 3.8e-05 23.3 0.2 0.11 11.9 0.0 3.2 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 EEQ69884.1 - 6.2e-05 22.3 0.0 0.011 15.0 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_16 PF13191.1 EEQ69884.1 - 0.00079 19.4 0.1 0.0017 18.3 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EEQ69884.1 - 0.0034 17.1 0.0 0.091 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EEQ69884.1 - 0.0034 16.8 0.0 0.0087 15.5 0.0 1.6 1 1 0 1 1 1 1 FtsK/SpoIIIE family T2SE PF00437.15 EEQ69884.1 - 0.0062 15.4 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Zot PF05707.7 EEQ69884.1 - 0.0092 15.4 0.1 0.062 12.7 0.0 2.4 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) Flavi_DEAD PF07652.9 EEQ69884.1 - 0.0095 15.7 0.0 0.07 12.8 0.0 2.1 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_25 PF13481.1 EEQ69884.1 - 0.012 15.0 0.0 0.051 12.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 EEQ69884.1 - 0.012 15.7 0.3 0.052 13.7 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EEQ69884.1 - 0.02 14.3 0.0 0.11 11.9 0.0 2.0 1 1 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 EEQ69884.1 - 0.027 13.8 0.0 0.09 12.1 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein 4HB_MCP_1 PF12729.2 EEQ69884.1 - 0.041 13.2 0.0 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction NTPase_1 PF03266.10 EEQ69884.1 - 0.059 13.0 0.2 3.7 7.2 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.1 EEQ69884.1 - 0.06 13.2 0.0 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.1 EEQ69884.1 - 0.074 13.1 0.1 3 8.0 0.0 2.8 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain FlxA PF14282.1 EEQ69886.1 - 0.0098 15.8 1.1 0.0098 15.8 0.8 2.3 3 0 0 3 3 3 1 FlxA-like protein PIG-F PF06699.6 EEQ69887.1 - 5e-51 173.3 3.8 6.3e-51 173.0 2.7 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Aldo_ket_red PF00248.16 EEQ69888.1 - 7.7e-49 166.0 0.0 9.2e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Oxidored_molyb PF00174.14 EEQ69889.1 - 6e-47 159.1 0.0 1.5e-46 157.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EEQ69889.1 - 1.8e-36 124.6 0.6 1.8e-36 124.6 0.4 1.9 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.19 EEQ69889.1 - 3.8e-19 68.6 0.0 8.1e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 EEQ69889.1 - 1.4e-17 63.2 0.1 3.5e-17 61.9 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.16 EEQ69889.1 - 5.5e-16 59.0 0.0 2.8e-15 56.8 0.0 2.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EEQ69889.1 - 0.088 12.7 0.0 0.45 10.4 0.0 2.2 1 1 1 2 2 2 0 Ferric reductase NAD binding domain Hydrolase_4 PF12146.3 EEQ69890.1 - 0.035 13.9 0.1 0.73 9.7 0.0 2.9 3 0 0 3 3 3 0 Putative lysophospholipase Cna_B PF05738.8 EEQ69890.1 - 0.048 13.4 0.6 0.58 9.9 0.0 2.9 3 0 0 3 3 3 0 Cna protein B-type domain MutS_I PF01624.15 EEQ69890.1 - 0.078 13.0 0.0 15 5.6 0.0 2.3 2 0 0 2 2 2 0 MutS domain I malic PF00390.14 EEQ69892.1 - 0.014 14.9 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 Malic enzyme, N-terminal domain Sugar_tr PF00083.19 EEQ69894.1 - 3.9e-78 263.0 24.3 4.5e-78 262.8 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ69894.1 - 1.6e-14 53.4 34.2 3.3e-09 35.9 11.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF46 PF01864.12 EEQ69894.1 - 0.013 15.3 5.2 0.94 9.3 0.1 2.6 2 1 0 2 2 2 0 Putative integral membrane protein DUF46 LysM PF01476.15 EEQ69895.1 - 4.4e-10 39.2 0.0 0.00047 19.9 0.0 2.4 2 0 0 2 2 2 2 LysM domain RhoGAP PF00620.22 EEQ69896.1 - 8e-35 119.6 0.0 1.5e-34 118.8 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Ribosomal_L32e PF01655.13 EEQ69896.1 - 0.0036 17.3 0.3 0.0075 16.2 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L32 STAT_int PF02865.12 EEQ69896.1 - 0.2 11.6 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 STAT protein, protein interaction domain zf-Tim10_DDP PF02953.10 EEQ69898.1 - 2.1e-19 68.5 4.8 3e-19 68.0 3.3 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger MSP1b PF03429.8 EEQ69898.1 - 0.039 11.8 0.4 0.043 11.7 0.3 1.0 1 0 0 1 1 1 0 Major surface protein 1B GED PF02212.13 EEQ69898.1 - 0.068 13.0 0.1 0.085 12.7 0.1 1.1 1 0 0 1 1 1 0 Dynamin GTPase effector domain Connexin PF00029.14 EEQ69898.1 - 0.088 12.8 0.5 0.11 12.5 0.4 1.2 1 0 0 1 1 1 0 Connexin DUF842 PF05811.8 EEQ69898.1 - 0.092 12.2 4.9 0.19 11.1 2.8 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Vicilin_N PF04702.7 EEQ69898.1 - 0.18 11.3 5.3 0.24 11.0 3.7 1.2 1 0 0 1 1 1 0 Vicilin N terminal region Beta_elim_lyase PF01212.16 EEQ69899.1 - 4.8e-65 219.5 0.0 6e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EEQ69899.1 - 0.0011 18.1 0.0 0.0077 15.3 0.0 2.2 2 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EEQ69899.1 - 0.055 11.7 0.0 0.092 11.0 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF1455 PF07306.6 EEQ69900.1 - 0.057 13.4 0.3 0.062 13.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) KdgT PF03812.8 EEQ69900.1 - 0.46 9.5 3.8 0.52 9.4 2.6 1.0 1 0 0 1 1 1 0 2-keto-3-deoxygluconate permease ADH_N PF08240.7 EEQ69901.1 - 3e-28 97.7 2.3 7.5e-28 96.4 1.6 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ69901.1 - 2.4e-19 69.1 0.1 4.9e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Saccharop_dh PF03435.13 EEQ69901.1 - 0.0011 18.1 0.0 0.0019 17.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase Pyr_redox_3 PF13738.1 EEQ69901.1 - 0.0088 16.1 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EEQ69901.1 - 0.012 14.9 0.1 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 EEQ69901.1 - 0.033 14.2 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Gp_dh_N PF00044.19 EEQ69901.1 - 0.042 13.8 0.6 2.5 8.0 0.2 2.7 2 1 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EEQ69901.1 - 0.094 13.1 0.1 0.34 11.3 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_5 PF07994.7 EEQ69903.1 - 5.5e-113 377.3 0.1 6.5e-113 377.0 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EEQ69903.1 - 1.2e-45 153.9 0.9 2.2e-45 153.1 0.6 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF1459 PF07312.6 EEQ69903.1 - 0.0021 17.9 0.2 0.028 14.3 0.2 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1459) HNOBA PF07701.9 EEQ69904.1 - 0.076 12.2 0.0 0.083 12.0 0.0 1.1 1 0 0 1 1 1 0 Heme NO binding associated APH PF01636.18 EEQ69906.1 - 5.5e-15 55.7 0.0 7.8e-14 51.9 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EEQ69906.1 - 0.013 14.6 0.0 0.096 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain RIO1 PF01163.17 EEQ69906.1 - 0.014 14.7 0.0 0.05 12.9 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Fructosamin_kin PF03881.9 EEQ69906.1 - 0.021 13.7 0.0 0.69 8.8 0.0 2.0 2 0 0 2 2 2 0 Fructosamine kinase EcKinase PF02958.15 EEQ69906.1 - 0.038 13.1 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DUF3435 PF11917.3 EEQ69907.1 - 1.1e-06 27.6 3.7 1.6e-06 27.0 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Bunya_NS-S PF01104.12 EEQ69908.1 - 0.049 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-s LIM PF00412.17 EEQ69909.1 - 2.5e-19 69.0 16.0 6.3e-12 45.3 2.4 3.0 3 1 0 3 3 3 2 LIM domain mono-CXXC PF15626.1 EEQ69909.1 - 1.1 9.2 8.2 2.7 7.9 0.4 3.8 2 0 0 2 2 2 0 single CXXC unit S1-P1_nuclease PF02265.11 EEQ69910.1 - 6.4e-13 48.9 0.0 2.3e-05 24.1 0.0 2.1 1 1 0 2 2 2 2 S1/P1 Nuclease Methyltransf_23 PF13489.1 EEQ69913.1 - 1.1e-22 80.4 0.0 1.7e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ69913.1 - 1.8e-09 38.1 0.1 4.2e-08 33.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ69913.1 - 6.2e-09 35.6 0.1 9.6e-08 31.7 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ69913.1 - 5.9e-07 29.8 0.0 1.1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ69913.1 - 0.00029 21.2 0.0 0.003 17.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ69913.1 - 0.0069 16.4 0.0 0.067 13.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ69913.1 - 0.02 14.2 0.0 0.62 9.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain GRAS PF03514.9 EEQ69913.1 - 0.036 12.7 0.1 0.053 12.2 0.1 1.2 1 0 0 1 1 1 0 GRAS domain family Methyltransf_25 PF13649.1 EEQ69913.1 - 0.04 14.2 0.0 0.1 12.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EEQ69913.1 - 0.1 11.6 0.0 0.22 10.5 0.0 1.5 1 1 1 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 EEQ69913.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DEAD PF00270.24 EEQ69914.1 - 2.4e-35 121.5 0.4 3.3e-34 117.8 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ69914.1 - 1.3e-21 76.2 0.3 2.6e-21 75.2 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ69914.1 - 0.039 13.7 0.0 0.14 11.9 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EEQ69914.1 - 0.047 13.2 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF3217 PF11506.3 EEQ69914.1 - 0.065 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3217) CMS1 PF14617.1 EEQ69914.1 - 0.081 11.9 0.0 0.16 10.9 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit tRNA-synt_1b PF00579.20 EEQ69914.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) FCH PF00611.18 EEQ69915.1 - 9.2e-23 80.2 0.5 2.8e-22 78.7 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 EEQ69915.1 - 3.9e-21 74.3 0.5 3.3e-12 45.7 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EEQ69915.1 - 6.3e-16 57.4 0.1 2.1e-07 30.2 0.1 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.17 EEQ69915.1 - 1.7e-14 53.2 5.2 2.8e-14 52.5 3.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Ax_dynein_light PF10211.4 EEQ69915.1 - 0.011 15.6 5.1 0.011 15.6 3.5 2.5 2 0 0 2 2 2 0 Axonemal dynein light chain SH3_2 PF07653.12 EEQ69915.1 - 0.022 14.2 0.2 3.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Variant SH3 domain SH3_3 PF08239.6 EEQ69915.1 - 0.09 12.9 0.8 0.89 9.7 0.1 2.4 2 0 0 2 2 2 0 Bacterial SH3 domain C1_2 PF03107.11 EEQ69915.1 - 0.56 10.3 7.8 0.99 9.5 5.4 1.4 1 0 0 1 1 1 0 C1 domain Glyco_hydro_72 PF03198.9 EEQ69916.1 - 3e-115 384.5 0.9 4e-115 384.1 0.6 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EEQ69916.1 - 2.5e-07 30.1 0.1 6.4e-07 28.8 0.1 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Choline_kinase PF01633.15 EEQ69918.1 - 0.098 12.2 0.4 0.19 11.2 0.2 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase Arginase PF00491.16 EEQ69920.1 - 1.8e-76 257.0 0.7 2.3e-76 256.7 0.5 1.1 1 0 0 1 1 1 1 Arginase family GAF_2 PF13185.1 EEQ69921.1 - 1.9e-10 41.3 0.0 4.2e-10 40.2 0.0 1.5 2 0 0 2 2 2 1 GAF domain GAF PF01590.21 EEQ69921.1 - 2.2e-06 27.9 0.0 3.2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EEQ69921.1 - 2.3e-05 24.5 0.0 3.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 GAF domain NAD_kinase PF01513.16 EEQ69923.1 - 8.1e-66 221.6 0.0 1e-65 221.3 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Pro-kuma_activ PF09286.6 EEQ69924.1 - 1.6e-33 115.7 0.0 3.7e-33 114.5 0.0 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EEQ69924.1 - 0.0016 17.6 0.0 0.0023 17.1 0.0 1.2 1 0 0 1 1 1 1 Subtilase family DUF4244 PF14029.1 EEQ69926.1 - 0.016 14.3 0.0 0.038 13.0 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4244) RNase_PH PF01138.16 EEQ69927.1 - 0.0005 20.3 0.0 0.00083 19.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 E1-E2_ATPase PF00122.15 EEQ69929.1 - 1.2e-61 207.6 10.1 1.2e-61 207.6 7.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEQ69929.1 - 5.2e-33 114.0 4.3 5.2e-33 114.0 3.0 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEQ69929.1 - 7.1e-28 98.4 0.0 2.1e-27 96.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEQ69929.1 - 5.8e-17 60.9 1.5 6.3e-17 60.8 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EEQ69929.1 - 2e-13 50.1 0.0 3.9e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EEQ69929.1 - 2.6e-11 44.0 0.1 8.7e-11 42.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEQ69929.1 - 1.3e-05 24.9 1.3 1.3e-05 24.9 0.9 2.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF2014 PF09427.5 EEQ69930.1 - 3e-110 367.4 1.6 4.2e-110 366.9 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 EEQ69930.1 - 1.6e-17 62.9 0.7 1.6e-17 62.9 0.5 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF3176 PF11374.3 EEQ69930.1 - 0.054 13.3 0.6 0.59 10.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) bZIP_1 PF00170.16 EEQ69930.1 - 0.27 11.2 6.3 0.15 12.0 2.4 2.0 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 EEQ69930.1 - 0.49 10.2 7.3 0.56 10.0 2.2 2.2 2 0 0 2 2 2 0 Basic region leucine zipper DHDPS PF00701.17 EEQ69931.1 - 7e-43 146.2 0.0 8.1e-43 146.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family zf-MYND PF01753.13 EEQ69932.1 - 2.8e-09 36.6 14.7 7.5e-09 35.3 10.2 1.8 1 0 0 1 1 1 1 MYND finger DUF4470 PF14737.1 EEQ69932.1 - 9.8e-05 22.0 0.2 0.0011 18.6 0.1 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4470) Med31 PF05669.7 EEQ69932.1 - 0.11 12.2 0.5 0.3 10.8 0.3 1.7 1 0 0 1 1 1 0 SOH1 Pectate_lyase_3 PF12708.2 EEQ69933.1 - 3.2e-68 230.2 22.0 1.8e-57 195.0 6.7 3.2 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EEQ69933.1 - 1.6e-07 30.6 2.3 0.0039 16.6 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Varsurf_PPLC PF03490.8 EEQ69933.1 - 0.0015 18.1 0.2 0.0052 16.4 0.1 1.9 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C EGF PF00008.22 EEQ69937.1 - 2.8 8.0 9.7 5.7 7.0 2.5 2.4 2 0 0 2 2 2 0 EGF-like domain Methyltransf_23 PF13489.1 EEQ69939.1 - 3e-10 40.0 0.1 4.5e-10 39.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Spore_coat_CotO PF14153.1 EEQ69939.1 - 4.3e-05 23.0 2.0 4.8e-05 22.8 1.4 1.2 1 0 0 1 1 1 1 Spore coat protein CotO eIF-3c_N PF05470.7 EEQ69939.1 - 0.0098 14.0 0.3 0.0091 14.1 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Radial_spoke PF04712.7 EEQ69939.1 - 0.013 14.3 12.2 0.02 13.6 8.4 1.4 1 0 0 1 1 1 0 Radial spokehead-like protein RRN3 PF05327.6 EEQ69939.1 - 0.017 13.2 6.1 0.02 13.0 4.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.7 EEQ69939.1 - 0.051 12.8 17.3 0.065 12.5 12.0 1.1 1 0 0 1 1 1 0 SDA1 Ycf1 PF05758.7 EEQ69939.1 - 0.077 10.7 5.1 0.088 10.5 3.6 1.1 1 0 0 1 1 1 0 Ycf1 Methyltransf_18 PF12847.2 EEQ69939.1 - 0.078 13.5 0.1 11 6.6 0.0 2.4 1 1 1 2 2 2 0 Methyltransferase domain Tim54 PF11711.3 EEQ69939.1 - 0.098 11.2 5.7 0.14 10.7 4.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SAPS PF04499.10 EEQ69939.1 - 0.17 10.4 3.3 0.21 10.1 2.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Vfa1 PF08432.5 EEQ69939.1 - 0.29 11.1 10.5 0.43 10.5 7.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DARPP-32 PF05395.7 EEQ69939.1 - 0.49 10.5 12.3 0.73 9.9 8.5 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Sigma70_ner PF04546.8 EEQ69939.1 - 0.54 9.8 17.4 0.9 9.1 12.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DHHW PF14286.1 EEQ69939.1 - 0.67 9.2 5.5 0.97 8.6 3.8 1.1 1 0 0 1 1 1 0 DHHW protein BUD22 PF09073.5 EEQ69939.1 - 0.68 8.9 19.6 1.1 8.2 13.6 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EEQ69939.1 - 0.7 7.7 28.1 0.98 7.2 19.5 1.1 1 0 0 1 1 1 0 Nop14-like family PI3K_1B_p101 PF10486.4 EEQ69939.1 - 1.1 6.7 5.1 1.6 6.1 3.5 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit D123 PF07065.9 EEQ69939.1 - 1.2 8.1 6.0 1.9 7.4 4.1 1.2 1 0 0 1 1 1 0 D123 Daxx PF03344.10 EEQ69939.1 - 1.3 7.4 28.7 1.7 7.0 19.9 1.1 1 0 0 1 1 1 0 Daxx Family Pox_Ag35 PF03286.9 EEQ69939.1 - 1.6 8.2 13.5 2.4 7.6 9.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein HABP4_PAI-RBP1 PF04774.10 EEQ69939.1 - 1.9 9.0 26.9 3.1 8.3 18.6 1.2 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Prothymosin PF03247.9 EEQ69939.1 - 2 8.6 44.5 3.2 7.9 30.8 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family Sporozoite_P67 PF05642.6 EEQ69939.1 - 2.1 6.1 8.7 3 5.6 6.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RNA_pol_3_Rpc31 PF11705.3 EEQ69939.1 - 2.1 8.2 29.4 3.4 7.5 20.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RNA_pol_Rpc4 PF05132.9 EEQ69939.1 - 2.1 8.3 8.1 3.4 7.6 5.6 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Prog_receptor PF02161.10 EEQ69939.1 - 3.7 6.2 8.9 4.9 5.8 6.2 1.1 1 0 0 1 1 1 0 Progesterone receptor Rhabdo_ncap PF00945.13 EEQ69939.1 - 3.7 6.0 7.7 5.4 5.4 5.3 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Zip PF02535.17 EEQ69939.1 - 3.8 6.4 6.6 5.8 5.8 4.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TRAP_alpha PF03896.11 EEQ69939.1 - 4.7 6.1 17.8 4.8 6.1 11.6 1.4 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit AAA PF00004.24 EEQ69940.1 - 5e-16 59.1 0.0 1.3e-15 57.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 EEQ69940.1 - 2.1e-08 34.0 0.2 3.2e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA_25 PF13481.1 EEQ69940.1 - 0.00059 19.2 0.0 0.0014 18.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EEQ69940.1 - 0.0052 15.5 0.0 0.011 14.4 0.0 1.5 2 0 0 2 2 2 1 TIP49 C-terminus AAA_18 PF13238.1 EEQ69940.1 - 0.0061 16.8 0.1 0.02 15.1 0.0 2.0 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EEQ69940.1 - 0.0074 15.3 0.0 0.015 14.4 0.0 1.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EEQ69940.1 - 0.0074 17.1 0.0 0.025 15.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EEQ69940.1 - 0.0082 15.8 0.0 0.026 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EEQ69940.1 - 0.012 15.2 0.1 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EEQ69940.1 - 0.017 14.5 0.0 0.056 12.8 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 EEQ69940.1 - 0.044 13.7 0.0 0.52 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EEQ69940.1 - 0.072 13.3 0.0 0.25 11.6 0.0 2.0 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 EEQ69940.1 - 0.081 12.7 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EEQ69940.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.1 EEQ69940.1 - 0.13 12.3 0.0 0.41 10.7 0.0 2.0 2 1 0 2 2 1 0 AAA domain DUF1769 PF08588.5 EEQ69941.1 - 2.5e-05 24.1 8.5 24 4.9 0.0 6.2 1 1 5 6 6 6 5 Protein of unknown function (DUF1769) APH PF01636.18 EEQ69944.1 - 3.3e-13 49.9 0.0 5.3e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RTC4 PF14474.1 EEQ69945.1 - 4.9e-29 100.8 0.0 6.6e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 RTC4-like domain MiaE PF06175.6 EEQ69945.1 - 0.02 14.2 0.0 0.022 14.1 0.0 1.1 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) DUF1708 PF08101.6 EEQ69948.1 - 0.058 12.2 0.0 0.07 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Mito_carr PF00153.22 EEQ69949.1 - 8.2e-57 188.9 0.3 1.5e-19 69.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pex24p PF06398.6 EEQ69950.1 - 2.7e-88 296.1 0.0 3.3e-88 295.9 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.7 EEQ69950.1 - 0.027 12.6 0.8 0.041 12.0 0.5 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) PRT_C PF08372.5 EEQ69950.1 - 0.063 12.7 0.3 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal DUF3292 PF11696.3 EEQ69950.1 - 0.15 9.9 2.4 0.22 9.3 1.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3292) Keratin PF02422.11 EEQ69951.1 - 1.1 9.2 5.4 0.46 10.4 1.7 1.8 1 1 1 2 2 2 0 Keratin Nop16 PF09420.5 EEQ69952.1 - 9.5e-60 201.4 5.6 1.1e-59 201.2 3.9 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Ribosomal_L37e PF01907.14 EEQ69953.1 - 3.9e-27 93.7 11.2 6.5e-27 93.0 7.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EEQ69953.1 - 0.00087 19.0 2.6 0.0013 18.4 1.8 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 EEQ69953.1 - 0.078 12.2 1.7 1 8.6 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EEQ69953.1 - 0.17 11.4 2.4 4.3 6.9 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_6 PF14599.1 EEQ69953.1 - 0.18 11.5 2.6 0.26 11.1 1.8 1.2 1 0 0 1 1 1 0 Zinc-ribbon DUF35_N PF12172.3 EEQ69953.1 - 0.33 10.9 4.1 0.64 10.0 2.9 1.5 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) GFA PF04828.9 EEQ69953.1 - 0.63 10.0 5.0 5.7 6.9 0.2 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_L32p PF01783.18 EEQ69953.1 - 1.2 9.3 6.9 13 6.0 4.8 2.3 1 1 0 1 1 1 0 Ribosomal L32p protein family Ribosomal_S14 PF00253.16 EEQ69953.1 - 1.4 8.3 8.9 2.4 7.5 0.5 2.6 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e zf-HYPF PF07503.7 EEQ69953.1 - 6.5 6.2 7.1 27 4.2 4.5 2.1 1 1 1 2 2 2 0 HypF finger DUF2348 PF09807.4 EEQ69954.1 - 2.4e-08 33.4 0.0 7.2e-05 22.0 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2348) RdRP PF05183.7 EEQ69955.1 - 1.3e-184 615.1 0.1 2.5e-184 614.2 0.1 1.4 2 0 0 2 2 2 1 RNA dependent RNA polymerase DUF3847 PF12958.2 EEQ69955.1 - 6.4 6.6 13.1 28 4.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) FAD-oxidase_C PF02913.14 EEQ69956.1 - 2.4e-61 207.2 0.0 3.5e-61 206.6 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EEQ69956.1 - 1.6e-34 118.3 0.1 3.6e-34 117.1 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Ribosomal_S4e PF00900.15 EEQ69957.1 - 2e-32 110.7 0.3 4.5e-32 109.5 0.2 1.6 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EEQ69957.1 - 1.2e-18 66.6 4.9 2.3e-18 65.7 3.4 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EEQ69957.1 - 2.8e-05 23.4 0.0 5.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EEQ69957.1 - 0.0028 17.3 0.6 0.0028 17.3 0.4 3.2 4 0 0 4 4 4 1 KOW motif DUF4522 PF15022.1 EEQ69958.1 - 0.1 12.2 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) RasGEF PF00617.14 EEQ69959.1 - 0.0017 18.0 0.0 0.0073 16.0 0.0 2.0 1 1 0 1 1 1 1 RasGEF domain Myb_DNA-bind_6 PF13921.1 EEQ69962.1 - 5e-13 48.9 0.0 3.2e-06 27.1 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEQ69962.1 - 1.4e-10 41.0 1.0 0.00022 21.2 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain PX PF00787.19 EEQ69963.1 - 3.7e-14 52.4 0.0 5.4e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 PX domain WD40 PF00400.27 EEQ69964.1 - 2e-22 78.1 22.5 4.7e-08 32.6 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EEQ69964.1 - 0.086 11.1 6.5 1.3 7.2 0.1 3.8 4 1 1 5 5 5 0 Cytochrome D1 heme domain PD40 PF07676.7 EEQ69964.1 - 0.15 11.7 0.0 0.15 11.7 0.0 3.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat SecE PF00584.15 EEQ69965.1 - 6.3e-13 48.0 0.0 7.5e-13 47.8 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex RRM_6 PF14259.1 EEQ69966.1 - 2e-10 40.5 0.0 3.4e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEQ69966.1 - 2.2e-07 30.3 0.0 3.8e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ69966.1 - 0.00058 19.6 0.1 0.0011 18.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 PF05764.8 EEQ69966.1 - 0.25 10.9 3.7 0.21 11.1 0.5 1.9 2 0 0 2 2 2 0 YL1 nuclear protein zf-C2H2_4 PF13894.1 EEQ69967.1 - 1.1e-05 25.3 0.5 0.013 15.8 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ69967.1 - 0.00037 20.6 1.1 0.14 12.5 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 EEQ69967.1 - 0.002 18.2 0.1 0.53 10.6 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 EEQ69967.1 - 0.029 14.6 2.1 1.7 9.1 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-met2 PF12907.2 EEQ69967.1 - 0.038 13.9 0.1 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding Pyr_redox_3 PF13738.1 EEQ69968.1 - 3.4e-16 59.9 0.0 9.9e-16 58.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEQ69968.1 - 8.8e-07 28.9 0.0 0.00014 21.8 0.0 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EEQ69968.1 - 8.5e-05 20.9 0.0 0.022 12.9 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EEQ69968.1 - 0.0001 22.2 0.0 0.00027 20.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EEQ69968.1 - 0.00018 20.6 0.0 0.00038 19.6 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EEQ69968.1 - 0.0039 16.1 0.0 0.0079 15.1 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.1 EEQ69968.1 - 0.0039 16.1 0.0 2.1 7.1 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EEQ69968.1 - 0.004 16.9 0.0 4 7.2 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EEQ69968.1 - 0.0045 15.9 0.0 0.065 12.1 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 EEQ69968.1 - 0.039 13.0 0.0 0.27 10.2 0.0 2.0 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 EEQ69968.1 - 0.044 12.2 0.0 0.12 10.8 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 EEQ69968.1 - 0.12 11.1 0.0 1.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EEQ69968.1 - 0.15 10.8 0.0 0.3 9.8 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.14 EEQ69968.1 - 0.19 10.8 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Mito_carr PF00153.22 EEQ69972.1 - 1.5e-78 258.6 2.2 2.7e-25 87.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L21e PF01157.13 EEQ69973.1 - 4.7e-40 135.3 7.6 8.3e-40 134.6 5.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L21e Ribosomal_S4 PF00163.14 EEQ69974.1 - 1e-29 102.7 1.3 2e-29 101.7 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EEQ69974.1 - 8.9e-13 47.4 1.6 8.9e-13 47.4 1.1 2.3 3 0 0 3 3 3 1 S4 domain AAA_13 PF13166.1 EEQ69975.1 - 0.0075 14.7 2.5 0.01 14.3 1.7 1.1 1 0 0 1 1 1 1 AAA domain BLOC1_2 PF10046.4 EEQ69975.1 - 0.024 14.7 1.4 0.024 14.7 1.0 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-C4H2 PF10146.4 EEQ69975.1 - 0.034 14.1 2.4 0.057 13.4 1.6 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein HR1 PF02185.11 EEQ69975.1 - 0.047 13.4 0.2 0.047 13.4 0.1 2.9 2 1 1 3 3 3 0 Hr1 repeat Prefoldin PF02996.12 EEQ69975.1 - 0.13 11.9 5.4 1.1 8.9 1.0 2.9 1 1 3 4 4 4 0 Prefoldin subunit Tropomyosin_1 PF12718.2 EEQ69975.1 - 0.24 11.2 10.3 0.02 14.7 1.5 2.3 1 1 1 2 2 2 0 Tropomyosin like ISG65-75 PF11727.3 EEQ69975.1 - 0.25 10.3 3.5 0.94 8.4 0.5 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein Spc7 PF08317.6 EEQ69975.1 - 0.3 9.6 7.4 0.098 11.2 0.7 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.7 EEQ69975.1 - 0.32 10.7 13.9 0.22 11.2 3.6 2.8 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.7 EEQ69975.1 - 0.51 10.1 3.3 1.2 8.9 0.4 2.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin_2 PF01920.15 EEQ69975.1 - 0.75 9.5 9.2 0.47 10.2 1.6 3.1 2 1 1 3 3 3 0 Prefoldin subunit IFP_35_N PF07334.8 EEQ69975.1 - 0.98 9.4 3.8 3.6 7.6 2.6 2.1 1 1 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus FlaC_arch PF05377.6 EEQ69975.1 - 1.4 8.8 4.9 13 5.7 0.0 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) IncA PF04156.9 EEQ69975.1 - 3.3 7.2 14.1 1 8.9 2.7 2.3 1 1 1 2 2 2 0 IncA protein Atg14 PF10186.4 EEQ69975.1 - 3.8 6.3 10.1 15 4.3 6.9 1.8 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3552 PF12072.3 EEQ69975.1 - 5.3 6.2 13.1 2.2 7.4 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Bap31 PF05529.7 EEQ69975.1 - 5.8 6.3 6.0 1.2 8.5 0.3 2.4 1 1 2 3 3 3 0 B-cell receptor-associated protein 31-like APG6 PF04111.7 EEQ69975.1 - 9.8 5.1 8.0 6.6 5.6 0.9 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 MBF1 PF08523.5 EEQ69976.1 - 0.0015 18.5 0.9 0.005 16.8 0.6 2.0 1 0 0 1 1 1 1 Multiprotein bridging factor 1 DUF946 PF06101.6 EEQ69979.1 - 2.2e-15 55.6 1.1 2e-11 42.6 0.3 2.1 2 0 0 2 2 2 2 Plant protein of unknown function (DUF946) NPP1 PF05630.6 EEQ69979.1 - 0.0038 16.9 0.2 0.0054 16.4 0.1 1.2 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) YcfA PF07927.7 EEQ69979.1 - 0.074 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 YcfA-like protein Septin PF00735.13 EEQ69980.1 - 3.9e-31 108.1 0.0 1.6e-11 43.7 0.0 3.1 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.13 EEQ69980.1 - 0.0031 17.0 0.0 0.0056 16.1 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF4165 PF13752.1 EEQ69980.1 - 0.0041 16.8 0.0 0.0092 15.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4165) Dynamin_N PF00350.18 EEQ69980.1 - 0.037 13.8 0.3 0.14 12.0 0.0 2.1 2 1 1 3 3 3 0 Dynamin family Miro PF08477.8 EEQ69980.1 - 0.042 14.3 0.0 0.095 13.1 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein G-alpha PF00503.15 EEQ69980.1 - 0.043 12.4 0.0 0.089 11.4 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.1 EEQ69980.1 - 0.094 12.6 0.0 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EEQ69980.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Annexin PF00191.15 EEQ69982.1 - 1e-16 60.5 4.3 0.0014 18.4 0.3 4.9 4 1 0 4 4 4 4 Annexin DUF4551 PF15087.1 EEQ69982.1 - 9.9 4.3 9.3 19 3.4 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Myb_DNA-binding PF00249.26 EEQ69984.1 - 0.044 13.8 0.0 0.095 12.7 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain UPF0016 PF01169.14 EEQ69985.1 - 8.2e-40 134.8 25.0 5.7e-21 74.4 5.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Gly-zipper_OmpA PF13436.1 EEQ69987.1 - 0.02 14.5 5.0 0.055 13.1 3.4 1.7 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain MFS_1 PF07690.11 EEQ69989.1 - 5.8e-22 77.8 27.6 5.8e-21 74.5 18.3 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ69989.1 - 4.2e-08 32.1 7.4 4.2e-08 32.1 5.1 3.2 2 2 1 3 3 3 2 Sugar (and other) transporter Gln-synt_C PF00120.19 EEQ69990.1 - 4.2e-44 150.6 0.0 1.4e-43 148.9 0.0 1.8 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 EEQ69990.1 - 3.6e-30 105.4 0.1 6.4e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase AP_endonuc_2 PF01261.19 EEQ69990.1 - 0.11 11.7 0.0 0.32 10.2 0.0 1.7 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Aldedh PF00171.17 EEQ69991.1 - 2.6e-152 507.3 0.0 3e-152 507.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UPF0542 PF15086.1 EEQ69992.1 - 0.14 11.9 1.6 0.31 10.8 1.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 AA_permease_2 PF13520.1 EEQ69993.1 - 1.2e-44 152.5 51.9 1.5e-44 152.2 36.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ69993.1 - 1.6e-23 82.8 47.0 2.1e-23 82.4 32.6 1.1 1 0 0 1 1 1 1 Amino acid permease Phospholamban PF04272.9 EEQ69993.1 - 0.026 13.9 0.7 18 4.9 1.3 2.9 2 0 0 2 2 2 0 Phospholamban Dpy19 PF10034.4 EEQ69993.1 - 2.4 6.2 9.3 0.12 10.4 1.4 2.0 2 0 0 2 2 2 0 Q-cell neuroblast polarisation DUF106 PF01956.11 EEQ69995.1 - 0.5 9.8 4.8 8.6 5.8 0.5 2.5 2 0 0 2 2 2 0 Integral membrane protein DUF106 Glyco_hydro_18 PF00704.23 EEQ69996.1 - 1.4e-18 67.4 0.0 2.6e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GPI2 PF06432.6 EEQ69997.1 - 7.7e-120 399.4 5.0 9.7e-120 399.1 3.5 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase CAF-1_p150 PF11600.3 EEQ69997.1 - 4 6.7 3.9 12 5.2 2.7 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Fumble PF03630.9 EEQ69998.1 - 6.9e-124 413.1 0.0 8.4e-123 409.5 0.0 2.0 1 1 0 1 1 1 1 Fumble Glyoxal_oxid_N PF07250.6 EEQ69999.1 - 3.5e-39 134.3 0.0 3.4e-38 131.0 0.0 2.4 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EEQ69999.1 - 1.2e-21 76.6 0.0 2.2e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Chitin_bind_1 PF00187.14 EEQ69999.1 - 0.0015 18.4 16.5 0.049 13.6 3.8 2.6 2 0 0 2 2 2 2 Chitin recognition protein RCC1_2 PF13540.1 EEQ69999.1 - 0.033 13.8 0.1 0.41 10.3 0.0 2.8 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat DEAD PF00270.24 EEQ70000.1 - 2.3e-39 134.6 0.0 1.1e-38 132.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ70000.1 - 1.1e-21 76.4 0.1 1.1e-21 76.4 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EEQ70000.1 - 0.00084 18.2 0.0 0.0011 17.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C_2 PF13307.1 EEQ70000.1 - 0.027 14.4 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain DUF1253 PF06862.7 EEQ70000.1 - 0.19 10.1 0.0 0.7 8.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) HC2 PF07382.6 EEQ70001.1 - 0.27 11.0 3.8 0.36 10.6 1.1 1.8 1 1 1 2 2 2 0 Histone H1-like nucleoprotein HC2 Polysacc_deac_1 PF01522.16 EEQ70005.1 - 9.4e-23 80.1 0.0 1.9e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase ThuA PF06283.6 EEQ70005.1 - 0.11 12.2 0.1 2.6 7.7 0.0 2.6 3 0 0 3 3 3 0 Trehalose utilisation DFP PF04127.10 EEQ70007.1 - 5e-13 49.0 0.0 2.5e-05 23.9 0.0 3.3 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein DUF427 PF04248.7 EEQ70008.1 - 0.043 13.4 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF427) CENP-O PF09496.5 EEQ70011.1 - 2e-29 101.6 0.0 3.1e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component Acetyltransf_3 PF13302.1 EEQ70013.1 - 3.2e-18 66.2 0.0 3.2e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acatn PF13000.2 EEQ70014.1 - 1e-150 502.9 25.1 1.3e-78 264.9 7.8 3.0 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 STAG PF08514.6 EEQ70015.1 - 7.1e-37 125.7 1.4 7.1e-37 125.7 1.0 2.7 3 0 0 3 3 3 1 STAG domain HEAT_2 PF13646.1 EEQ70015.1 - 3.5e-06 27.2 0.0 0.0057 16.9 0.0 3.7 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.17 EEQ70015.1 - 3.9e-05 23.3 0.1 7.1 7.0 0.0 5.0 4 0 0 4 4 4 2 HEAT repeat Cohesin_HEAT PF12765.2 EEQ70015.1 - 0.0043 16.9 1.5 0.2 11.6 0.2 3.4 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion DUF422 PF04240.7 EEQ70015.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF422) UreD PF01774.12 EEQ70016.1 - 2.6e-47 161.0 0.0 7.8e-47 159.4 0.0 1.7 1 1 0 1 1 1 1 UreD urease accessory protein CCER1 PF15482.1 EEQ70017.1 - 0.044 13.3 3.4 0.098 12.2 0.5 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing glutamate-rich protein family 1 Bud13 PF09736.4 EEQ70018.1 - 3.1 8.0 23.7 0.071 13.3 8.8 2.7 3 0 0 3 3 3 0 Pre-mRNA-splicing factor of RES complex TFIIF_alpha PF05793.7 EEQ70018.1 - 8.1 4.6 34.6 0.0062 14.9 9.0 2.4 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) S1 PF00575.18 EEQ70019.1 - 1e-82 272.2 39.5 1.6e-14 53.7 0.9 13.0 13 1 1 14 14 14 11 S1 RNA binding domain TPR_16 PF13432.1 EEQ70019.1 - 3.8e-08 33.7 0.0 0.76 10.5 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ70019.1 - 8.5e-07 29.2 0.1 1.1 9.5 0.1 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat Suf PF05843.9 EEQ70019.1 - 5.1e-05 23.1 11.4 0.18 11.4 0.1 4.3 2 1 2 4 4 4 3 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EEQ70019.1 - 0.00011 22.5 0.8 45 5.0 0.0 6.0 4 2 3 7 7 7 0 Tetratricopeptide repeat EXOSC1 PF10447.4 EEQ70019.1 - 0.00024 21.0 5.0 2.9 7.9 0.8 5.9 6 1 0 6 6 6 2 Exosome component EXOSC1/CSL4 TPR_11 PF13414.1 EEQ70019.1 - 0.0012 18.4 0.2 0.31 10.7 0.0 2.6 2 0 0 2 2 2 1 TPR repeat PPR PF01535.15 EEQ70019.1 - 0.0044 16.8 0.1 3.2 7.9 0.0 3.7 3 0 0 3 3 3 1 PPR repeat RNA_bind_2 PF10133.4 EEQ70019.1 - 0.078 13.0 0.6 0.31 11.1 0.4 2.1 1 0 0 1 1 1 0 Predicted RNA-binding protein TPR_7 PF13176.1 EEQ70019.1 - 0.085 12.7 0.1 4.1 7.4 0.0 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.27 EEQ70020.1 - 2.2e-25 87.5 10.6 7.7e-07 28.7 0.1 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Desmo_N PF06771.6 EEQ70020.1 - 0.016 15.1 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Viral Desmoplakin N-terminus Nup160 PF11715.3 EEQ70020.1 - 0.027 12.6 0.2 0.13 10.3 0.1 2.0 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Pex14_N PF04695.8 EEQ70020.1 - 0.33 10.9 0.1 0.33 10.9 0.0 3.1 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cpn60_TCP1 PF00118.19 EEQ70021.1 - 1.2e-142 475.9 14.2 1.4e-142 475.7 9.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family tRNA-synt_2b PF00587.20 EEQ70022.1 - 1.9e-21 76.4 0.0 3.2e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.6 EEQ70022.1 - 4.6e-17 61.6 3.0 1.2e-16 60.3 2.1 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 EEQ70022.1 - 9e-13 47.9 0.0 2.8e-12 46.4 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain NPR3 PF03666.8 EEQ70022.1 - 0.063 11.8 0.3 0.098 11.1 0.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NARP1 PF12569.3 EEQ70022.1 - 1.9 7.1 10.8 0.85 8.2 5.4 1.7 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF1590 PF07629.6 EEQ70025.1 - 0.039 13.5 0.2 0.083 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1590) RNase_PH PF01138.16 EEQ70026.1 - 8.2e-28 97.3 0.0 1.4e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 PEMT PF04191.8 EEQ70027.1 - 1.1e-57 192.6 9.1 2.5e-35 120.7 0.7 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase ParA PF10609.4 EEQ70029.1 - 8e-36 121.7 0.0 2.2e-35 120.3 0.0 1.7 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 EEQ70029.1 - 9e-17 61.1 0.0 1.3e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EEQ70029.1 - 5.3e-07 29.7 0.0 2.7e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EEQ70029.1 - 2.6e-06 26.7 1.7 0.0003 19.9 0.5 2.8 1 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 EEQ70029.1 - 0.00025 20.2 0.0 0.00047 19.3 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 EEQ70029.1 - 0.0012 18.5 0.0 0.33 10.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EEQ70029.1 - 0.01 15.4 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EEQ70029.1 - 0.011 14.9 0.1 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EEQ70029.1 - 0.021 14.2 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zn_Tnp_IS1595 PF12760.2 EEQ70029.1 - 0.052 13.3 0.1 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain AAA_17 PF13207.1 EEQ70029.1 - 0.056 14.2 0.0 0.12 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EEQ70029.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 EEQ70029.1 - 0.17 12.1 0.0 0.36 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain VirE PF05272.6 EEQ70029.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E Asp PF00026.18 EEQ70031.1 - 9.5e-60 202.4 0.4 1.1e-59 202.2 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EEQ70031.1 - 4.1e-08 33.6 1.7 0.0023 18.4 0.2 3.2 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EEQ70031.1 - 8.4e-06 25.8 0.0 6.2e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 EEQ70031.1 - 0.049 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease AnfO_nitrog PF09582.5 EEQ70031.1 - 0.19 10.8 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) tRNA_bind PF01588.15 EEQ70032.1 - 2.1e-21 75.5 0.0 8e-20 70.4 0.0 2.4 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 EEQ70032.1 - 1.3e-09 38.4 0.0 2.9e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEQ70032.1 - 9.9e-05 22.1 0.0 0.0003 20.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EEQ70032.1 - 0.0006 19.7 0.6 0.0012 18.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37_C PF11801.3 EEQ70032.1 - 0.15 11.9 1.5 9.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Tom37 C-terminal domain NPR3 PF03666.8 EEQ70032.1 - 0.28 9.6 8.3 0.44 9.0 5.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.7 EEQ70032.1 - 0.39 10.5 5.3 0.63 9.8 3.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Kelch_1 PF01344.20 EEQ70033.1 - 2.2e-34 116.7 6.3 1.3e-08 34.2 0.0 6.8 7 0 0 7 7 7 5 Kelch motif Kelch_6 PF13964.1 EEQ70033.1 - 9.1e-30 101.5 9.0 3.4e-08 33.3 0.0 6.1 4 1 3 7 7 7 5 Kelch motif Kelch_3 PF13415.1 EEQ70033.1 - 2.5e-25 88.0 8.9 1.9e-05 24.6 0.0 6.6 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EEQ70033.1 - 2.8e-24 84.6 9.7 1.9e-05 24.3 0.0 7.0 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EEQ70033.1 - 7.7e-21 73.6 8.4 0.00015 21.6 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EEQ70033.1 - 8.5e-16 57.0 5.9 0.00028 20.5 0.0 6.7 6 1 0 6 6 6 3 Kelch motif Anp1 PF03452.9 EEQ70034.1 - 9.8e-121 402.0 0.0 1.5e-120 401.3 0.0 1.3 1 0 0 1 1 1 1 Anp1 DUF2036 PF09724.4 EEQ70035.1 - 1.2e-16 60.8 0.0 5e-11 42.3 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2036) SH3_4 PF06347.8 EEQ70035.1 - 0.089 12.3 0.1 0.22 11.0 0.1 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain Acetyltransf_7 PF13508.1 EEQ70036.1 - 0.00021 21.3 0.0 0.00058 19.9 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ70036.1 - 0.00083 19.0 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EEQ70036.1 - 0.0072 16.1 0.0 0.029 14.2 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEQ70036.1 - 0.018 15.0 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family IBR PF01485.16 EEQ70037.1 - 9.1e-08 31.8 10.2 9.1e-08 31.8 7.1 3.7 3 1 0 3 3 3 2 IBR domain HORMA PF02301.13 EEQ70038.1 - 7.5e-22 77.8 0.2 1.3e-21 77.0 0.0 1.5 2 0 0 2 2 2 1 HORMA domain PalH PF08733.5 EEQ70038.1 - 0.078 11.8 0.7 0.12 11.2 0.5 1.2 1 0 0 1 1 1 0 PalH/RIM21 Herpes_UL73 PF03554.8 EEQ70038.1 - 0.19 11.5 2.6 0.46 10.3 1.8 1.6 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein Methyltransf_21 PF05050.7 EEQ70038.1 - 0.3 11.0 3.0 0.29 11.0 0.1 2.1 2 0 0 2 2 2 0 Methyltransferase FkbM domain gpUL132 PF11359.3 EEQ70038.1 - 0.91 8.8 9.5 2.2 7.5 6.6 1.6 1 0 0 1 1 1 0 Glycoprotein UL132 Dicty_REP PF05086.7 EEQ70038.1 - 3.2 5.3 7.4 5.1 4.7 5.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein IBN_N PF03810.14 EEQ70039.1 - 2e-07 30.8 4.9 3.7e-06 26.7 0.1 4.6 4 1 1 5 5 5 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EEQ70039.1 - 5.6e-05 23.0 0.5 0.0084 16.0 0.0 4.0 4 0 0 4 4 4 1 Exportin 1-like protein CAS_CSE1 PF03378.10 EEQ70039.1 - 0.00038 18.8 0.6 0.00071 17.9 0.1 1.6 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus HEAT PF02985.17 EEQ70039.1 - 0.026 14.5 0.2 2.6 8.3 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat ThiF PF00899.16 EEQ70040.1 - 1.7e-52 176.8 0.0 4.2e-32 110.8 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 EEQ70040.1 - 5.5e-41 137.9 3.3 1.9e-26 91.4 0.3 3.2 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 EEQ70040.1 - 1.1e-36 125.7 0.1 2.7e-36 124.4 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 EEQ70040.1 - 3.1e-24 84.1 2.8 9.3e-21 72.9 0.4 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site GST_N_2 PF13409.1 EEQ70041.1 - 9.7e-23 79.9 0.1 3e-22 78.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEQ70041.1 - 7.8e-14 51.3 0.0 2.3e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EEQ70041.1 - 4.4e-06 26.8 0.2 0.00014 21.9 0.1 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEQ70041.1 - 0.00012 21.9 0.0 0.00027 20.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEQ70041.1 - 0.075 13.5 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Amidohydro_5 PF13594.1 EEQ70042.1 - 2.3e-11 43.3 0.6 9.1e-11 41.4 0.3 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 EEQ70042.1 - 0.00016 21.4 1.0 0.0014 18.3 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 EEQ70042.1 - 0.00069 19.7 0.1 0.1 12.6 0.1 2.9 2 1 1 3 3 3 1 Amidohydrolase Amidohydro_3 PF07969.6 EEQ70042.1 - 0.06 12.5 0.0 0.5 9.5 0.0 2.1 2 0 0 2 2 2 0 Amidohydrolase family Mito_carr PF00153.22 EEQ70043.1 - 1.7e-51 171.8 8.1 3.8e-23 81.0 0.1 4.3 3 1 1 4 4 4 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EEQ70043.1 - 1.1e-22 79.9 5.5 1.3e-14 54.0 0.4 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EEQ70043.1 - 1.5e-18 64.6 4.8 1.5e-05 23.9 0.2 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EEQ70043.1 - 1.5e-15 56.5 1.7 1.4e-06 27.7 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EEQ70043.1 - 5.6e-15 53.8 2.8 4.8e-05 22.5 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EEQ70043.1 - 5.9e-15 53.7 6.2 0.00018 21.1 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain SPARC_Ca_bdg PF10591.4 EEQ70043.1 - 8.9e-08 32.1 0.5 0.00026 21.0 0.1 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EEQ70043.1 - 0.00011 21.8 3.8 0.075 12.7 0.1 3.2 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 EEQ70043.1 - 0.05 13.2 0.0 2.6 7.7 0.0 2.5 2 0 0 2 2 2 0 EF hand UcrQ PF02939.11 EEQ70043.1 - 0.067 13.0 3.1 0.89 9.4 0.0 3.7 4 0 0 4 4 4 0 UcrQ family CRF PF00473.12 EEQ70043.1 - 0.15 12.1 0.0 0.45 10.6 0.0 1.8 1 0 0 1 1 1 0 Corticotropin-releasing factor family Cyclin_N PF00134.18 EEQ70044.1 - 7.3e-13 48.1 0.2 1.3e-11 44.1 0.1 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain DUF4452 PF14618.1 EEQ70045.1 - 7.2e-69 230.8 5.2 7.2e-69 230.8 3.6 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4452) Peptidase_S21 PF00716.12 EEQ70045.1 - 0.08 12.2 5.5 0.16 11.2 0.1 2.1 2 0 0 2 2 2 0 Assemblin (Peptidase family S21) FCP1_C PF09309.5 EEQ70045.1 - 0.67 9.2 6.8 1.5 8.0 4.7 1.6 1 0 0 1 1 1 0 FCP1, C-terminal MIP PF00230.15 EEQ70046.1 - 1.2e-46 159.0 13.8 1.6e-46 158.5 9.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF1090 PF06476.7 EEQ70047.1 - 0.84 9.3 7.3 23 4.6 5.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1090) SNARE PF05739.14 EEQ70048.1 - 2.7e-13 49.3 0.4 2.7e-13 49.3 0.3 2.0 2 1 0 2 2 2 1 SNARE domain FlxA PF14282.1 EEQ70048.1 - 0.00071 19.5 0.3 0.0012 18.7 0.2 1.4 1 0 0 1 1 1 1 FlxA-like protein Fzo_mitofusin PF04799.8 EEQ70048.1 - 0.017 14.5 0.4 0.034 13.5 0.1 1.6 2 0 0 2 2 2 0 fzo-like conserved region NPV_P10 PF05531.7 EEQ70048.1 - 0.042 14.0 0.1 0.37 11.0 0.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CENP-Q PF13094.1 EEQ70048.1 - 0.35 10.8 4.4 0.31 11.0 0.2 2.5 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit AMP-binding PF00501.23 EEQ70049.1 - 3.6e-57 193.6 0.0 5.2e-57 193.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 EEQ70049.1 - 1.4e-24 87.5 0.0 6.8e-24 85.3 0.0 2.0 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 EEQ70049.1 - 1.5e-08 34.7 0.3 3.3e-08 33.6 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EEQ70049.1 - 2.2e-05 24.4 0.0 6.1e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ70049.1 - 0.00063 19.5 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family GH3 PF03321.8 EEQ70049.1 - 0.012 14.1 0.1 0.41 9.0 0.0 2.4 3 0 0 3 3 3 0 GH3 auxin-responsive promoter ProSAAS PF07259.7 EEQ70049.1 - 0.12 11.8 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 ProSAAS precursor Trp_DMAT PF11991.3 EEQ70050.1 - 2.4e-75 254.0 0.0 2.7e-75 253.8 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Aminotran_MocR PF12897.2 EEQ70051.1 - 3.6e-08 32.3 0.0 7.9e-08 31.2 0.0 1.5 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_1_2 PF00155.16 EEQ70051.1 - 5.1e-08 32.2 0.0 4.9e-07 29.0 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II Pkinase PF00069.20 EEQ70052.1 - 8e-25 87.4 0.0 3.9e-24 85.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ70052.1 - 2.2e-11 43.3 0.0 1.9e-05 23.8 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEQ70052.1 - 3.2e-06 26.3 0.1 0.06 12.3 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.9 EEQ70052.1 - 0.0002 20.4 0.0 0.00069 18.7 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-TRAF PF02176.13 EEQ70053.1 - 3.9e-09 36.7 31.4 2e-06 28.0 7.0 3.6 1 1 2 3 3 3 2 TRAF-type zinc finger DUF2205 PF10224.4 EEQ70053.1 - 0.028 14.0 0.3 7.2 6.2 0.0 2.4 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Reo_sigmaC PF04582.7 EEQ70053.1 - 0.072 12.2 7.8 0.47 9.5 0.3 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein bZIP_2 PF07716.10 EEQ70053.1 - 0.12 12.2 0.4 0.31 10.8 0.2 1.8 2 0 0 2 2 2 0 Basic region leucine zipper DUF2360 PF10152.4 EEQ70053.1 - 1.2 9.3 5.8 3.6 7.8 4.0 1.8 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF1395 PF07160.7 EEQ70053.1 - 1.4 8.3 6.4 1.5 8.2 0.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1395) Sina PF03145.11 EEQ70053.1 - 1.9 8.1 20.2 3.9 7.0 1.7 2.8 1 1 0 2 2 2 0 Seven in absentia protein family Het-C PF07217.6 EEQ70054.1 - 2.9e-253 841.5 0.3 3.2e-252 838.1 0.2 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Zip PF02535.17 EEQ70054.1 - 0.68 8.8 5.9 1.3 7.9 4.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Spc97_Spc98 PF04130.8 EEQ70055.1 - 5.8e-76 255.9 0.0 7e-76 255.6 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family MFS_1 PF07690.11 EEQ70056.1 - 1.6e-30 106.0 38.6 2.4e-27 95.6 13.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EEQ70056.1 - 1.8e-05 24.4 2.6 0.0095 15.7 0.2 2.9 2 0 0 2 2 2 2 MFS_1 like family Serglycin PF04360.7 EEQ70056.1 - 0.00056 19.6 2.6 0.0012 18.5 1.8 1.6 1 0 0 1 1 1 1 Serglycin GILT PF03227.11 EEQ70059.1 - 2.4e-05 24.1 0.0 4.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Pkinase PF00069.20 EEQ70060.1 - 0.078 12.1 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.20 EEQ70061.1 - 1.6e-13 50.4 0.0 1.9e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ70061.1 - 1.7e-05 24.0 0.0 2.3e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Jiraiya PF15038.1 EEQ70061.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Jiraiya DUF1762 PF08574.5 EEQ70062.1 - 0.024 15.0 0.4 0.047 14.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1762) Ribosomal_S27 PF01599.14 EEQ70062.1 - 0.15 11.8 1.5 0.69 9.7 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S27a Ank PF00023.25 EEQ70063.1 - 1.5e-18 65.6 0.0 5.2e-09 35.4 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EEQ70063.1 - 1.1e-17 64.1 0.0 4.7e-08 33.2 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEQ70063.1 - 1.3e-15 57.4 0.1 1.8e-10 41.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ70063.1 - 5.6e-15 55.0 0.0 3.9e-08 33.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ70063.1 - 1.3e-13 49.6 0.0 4.9e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat 2-oxoacid_dh PF00198.18 EEQ70066.1 - 1.6e-80 269.6 0.1 2.6e-80 269.0 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EEQ70066.1 - 3.2e-17 61.9 1.0 5.5e-17 61.1 0.7 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 EEQ70066.1 - 0.001 18.2 0.9 0.048 12.8 0.1 2.4 1 1 2 3 3 3 2 HlyD family secretion protein DUF2360 PF10152.4 EEQ70066.1 - 0.081 13.2 7.9 0.14 12.4 5.5 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) 4HBT_3 PF13622.1 EEQ70066.1 - 0.09 12.5 0.6 0.14 11.8 0.4 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF605 PF04652.11 EEQ70066.1 - 0.19 11.1 11.2 0.25 10.7 7.7 1.1 1 0 0 1 1 1 0 Vta1 like Complex1_LYR PF05347.10 EEQ70067.1 - 1e-07 31.6 0.7 2.1e-07 30.6 0.5 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EEQ70067.1 - 2.1e-05 24.6 0.5 4.4e-05 23.5 0.3 1.6 1 0 0 1 1 1 1 Complex1_LYR-like Histone PF00125.19 EEQ70068.1 - 8.8e-26 89.8 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEQ70068.1 - 1.3e-05 25.1 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEQ70069.1 - 2.3e-22 78.9 0.2 3.3e-22 78.3 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEQ70069.1 - 6.8e-05 22.8 0.8 0.00011 22.2 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EEQ70069.1 - 0.00023 21.4 0.0 0.00038 20.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 EEQ70069.1 - 0.013 14.9 0.1 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF1018 PF06252.7 EEQ70069.1 - 0.056 13.9 0.1 0.081 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Peptidase_C54 PF03416.14 EEQ70071.1 - 4.3e-97 324.5 0.0 6.1e-97 324.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 Pap_E4 PF02711.9 EEQ70071.1 - 0.14 13.0 4.9 0.27 12.0 3.4 1.5 1 0 0 1 1 1 0 E4 protein R3H PF01424.17 EEQ70072.1 - 4.6e-12 45.4 0.0 1.4e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 EEQ70072.1 - 1e-10 41.1 0.2 2.2e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EEQ70072.1 - 0.00086 19.1 0.2 0.00086 19.1 0.1 3.5 4 0 0 4 4 4 1 DExH-box splicing factor binding site DnaJ PF00226.26 EEQ70073.1 - 7.3e-25 86.4 0.5 2.1e-24 85.0 0.3 1.9 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 EEQ70073.1 - 3.7e-09 36.4 3.7 3.7e-09 36.4 2.6 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEQ70073.1 - 3.2e-08 33.5 2.0 3.2e-08 33.5 1.4 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EEQ70073.1 - 5.2e-07 29.7 8.7 0.00044 20.3 0.8 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EEQ70073.1 - 0.00028 21.0 12.0 0.034 14.4 2.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ70073.1 - 0.0019 18.4 7.2 0.51 10.8 0.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger LIM PF00412.17 EEQ70073.1 - 0.077 13.0 4.7 5.3 7.1 0.3 2.5 2 0 0 2 2 2 0 LIM domain zf-C4pol PF14260.1 EEQ70073.1 - 0.15 12.0 3.0 0.72 9.8 0.4 2.6 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zf-H2C2_2 PF13465.1 EEQ70073.1 - 0.6 10.5 4.4 10 6.6 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 EEQ70073.1 - 0.66 9.9 9.4 4.1 7.4 1.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger SPX PF03105.14 EEQ70074.1 - 3.7e-38 131.9 0.0 5.1e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 EEQ70074.1 - 1.7e-07 30.9 7.8 1.7e-07 30.9 5.4 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EEQ70074.1 - 5.7e-06 25.8 9.6 1.9e-05 24.2 6.6 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ70074.1 - 1e-05 25.2 9.5 3.6e-05 23.5 6.6 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEQ70074.1 - 2.9e-05 23.6 7.6 6.3e-05 22.5 5.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ70074.1 - 0.00017 21.2 9.0 0.00017 21.2 6.2 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEQ70074.1 - 0.00021 21.2 10.8 0.00078 19.4 7.5 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EEQ70074.1 - 0.00084 19.0 6.6 0.0038 16.9 4.6 2.2 1 0 0 1 1 1 1 RING-type zinc-finger CotJA PF11007.3 EEQ70074.1 - 0.0079 15.8 0.0 0.024 14.2 0.0 1.8 1 0 0 1 1 1 1 Spore coat associated protein JA (CotJA) DUF3347 PF11827.3 EEQ70074.1 - 0.078 12.9 0.7 0.15 12.0 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Cas_Cas1 PF01867.11 EEQ70074.1 - 0.081 11.9 0.6 0.12 11.3 0.4 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas1 zf-P11 PF03854.9 EEQ70074.1 - 0.6 9.6 8.6 15 5.1 6.0 2.4 1 1 1 2 2 2 0 P-11 zinc finger zf-MIZ PF02891.15 EEQ70074.1 - 0.78 9.2 13.3 0.37 10.3 5.0 3.1 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger zf-RING_6 PF14835.1 EEQ70074.1 - 2.1 8.2 7.1 2.4 7.9 2.6 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EEQ70074.1 - 2.7 7.6 7.5 11 5.7 5.3 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain YccV-like PF08755.6 EEQ70075.1 - 1.8e-26 91.9 0.1 4.5e-26 90.6 0.0 1.7 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 EEQ70075.1 - 9.5e-14 51.1 0.0 2.3e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 EEQ70075.1 - 1.5e-07 31.0 0.9 3.3e-07 29.9 0.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ70075.1 - 1.5e-06 27.6 0.1 3.5e-06 26.5 0.1 1.7 1 0 0 1 1 1 1 F-box domain tRNA_lig_kinase PF08303.6 EEQ70076.1 - 0.038 13.8 0.1 0.068 13.0 0.1 1.4 1 0 0 1 1 1 0 tRNA ligase kinase domain Peptidase_C12 PF01088.16 EEQ70077.1 - 5.3e-62 208.7 0.0 9.6e-62 207.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 I-set PF07679.11 EEQ70078.1 - 0.0011 18.7 0.0 0.14 12.0 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin I-set domain DUF1918 PF08940.6 EEQ70078.1 - 0.0013 18.0 0.4 0.31 10.4 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF1918) Nrap PF03813.9 EEQ70079.1 - 0 1116.1 0.0 0 1115.9 0.0 1.0 1 0 0 1 1 1 1 Nrap protein Cys_Met_Meta_PP PF01053.15 EEQ70080.1 - 6.8e-32 110.2 0.0 9.1e-32 109.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF1330 PF07045.6 EEQ70080.1 - 0.059 13.2 0.0 4.3 7.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1330) Aminotran_1_2 PF00155.16 EEQ70080.1 - 0.11 11.4 0.0 0.26 10.2 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class I and II HNH_2 PF13391.1 EEQ70081.1 - 1e-11 44.3 0.2 2.5e-11 43.1 0.1 1.7 1 0 0 1 1 1 1 HNH endonuclease ATP-synt_E PF05680.7 EEQ70085.1 - 0.61 10.0 4.2 0.99 9.4 2.9 1.4 1 0 0 1 1 1 0 ATP synthase E chain MRP-L20 PF12824.2 EEQ70086.1 - 1.1e-59 201.1 5.3 1.3e-59 200.8 3.6 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 CENP-B_N PF04218.8 EEQ70086.1 - 0.053 12.9 0.0 0.15 11.4 0.0 1.8 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Peptidase_M20 PF01546.23 EEQ70087.1 - 1.4e-30 106.2 0.0 2e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EEQ70087.1 - 5.8e-15 55.0 0.0 9.2e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain SMC_N PF02463.14 EEQ70088.1 - 1.7e-23 83.0 2.5 5.8e-23 81.2 1.8 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEQ70088.1 - 9.7e-11 42.1 5.4 4.6e-07 30.0 0.3 2.9 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EEQ70088.1 - 1.2e-10 42.0 27.1 1.2e-10 42.0 18.8 4.9 2 2 0 2 2 1 1 AAA domain SMC_hinge PF06470.8 EEQ70088.1 - 0.00039 20.3 0.0 0.0013 18.6 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.1 EEQ70088.1 - 0.00049 19.2 5.6 0.00049 19.2 3.9 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EEQ70088.1 - 0.00052 19.4 0.0 0.00099 18.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EEQ70088.1 - 0.012 15.4 0.0 0.038 13.8 0.0 1.9 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Reo_sigmaC PF04582.7 EEQ70088.1 - 0.36 9.9 11.6 0.3 10.2 0.8 4.3 2 2 2 4 4 4 0 Reovirus sigma C capsid protein Adeno_PIX PF03955.9 EEQ70088.1 - 1.1 9.8 0.0 1.1 9.8 0.0 6.1 5 2 3 8 8 8 0 Adenovirus hexon-associated protein (IX) DUF4239 PF14023.1 EEQ70088.1 - 1.9 7.7 4.0 9 5.5 2.8 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) AAA_13 PF13166.1 EEQ70088.1 - 4.7 5.5 68.5 0.011 14.2 6.4 5.3 3 2 2 5 5 5 0 AAA domain DUF3435 PF11917.3 EEQ70089.1 - 8.1e-10 37.9 0.0 1.9e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) OAD_gamma PF04277.8 EEQ70090.1 - 0.074 13.4 0.0 0.2 12.0 0.0 1.6 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Sugar_tr PF00083.19 EEQ70091.1 - 1.1e-24 86.8 16.1 1.9e-13 49.8 5.1 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EEQ70091.1 - 0.00046 19.0 18.9 0.0029 16.3 13.1 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily LAB_N PF07578.6 EEQ70091.1 - 0.14 12.1 0.4 0.14 12.1 0.3 2.7 2 1 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain Drc1-Sld2 PF11719.3 EEQ70093.1 - 2.4e-116 389.3 20.7 5.3e-116 388.2 14.4 1.5 1 1 0 1 1 1 1 DNA replication and checkpoint protein Dicty_REP PF05086.7 EEQ70093.1 - 0.88 7.2 4.3 1.7 6.3 3.0 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-RING_2 PF13639.1 EEQ70094.1 - 5.9e-08 32.4 5.1 1.1e-07 31.6 3.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEQ70094.1 - 3.1e-07 29.9 2.7 4.5e-07 29.4 1.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ70094.1 - 1.1e-06 28.5 4.2 1.7e-06 27.9 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ70094.1 - 3e-06 26.7 4.2 4.7e-06 26.1 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEQ70094.1 - 0.00011 22.2 4.7 0.00033 20.6 3.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EEQ70094.1 - 0.22 11.2 2.5 0.37 10.5 1.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-MIZ PF02891.15 EEQ70094.1 - 0.8 9.2 4.8 1.4 8.4 3.3 1.3 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF2410 PF10307.4 EEQ70095.1 - 6.4e-51 172.5 0.0 8.5e-51 172.1 0.0 1.1 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) Fig1 PF12351.3 EEQ70096.1 - 5.4e-55 186.1 4.2 5.4e-55 186.1 2.9 1.9 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EEQ70096.1 - 1e-08 35.0 7.2 2.2e-08 33.9 5.0 1.5 1 1 0 1 1 1 1 SUR7/PalI family XPG_I PF00867.13 EEQ70098.1 - 7.4e-25 86.8 0.1 1.6e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EEQ70098.1 - 1.6e-18 66.8 0.0 4.5e-18 65.3 0.0 1.7 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.2 EEQ70098.1 - 0.0019 17.7 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing DUF4620 PF15399.1 EEQ70098.1 - 0.066 13.3 0.3 0.16 12.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) TPR_2 PF07719.12 EEQ70098.1 - 0.1 12.5 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2962 PF11176.3 EEQ70099.1 - 1.1e-51 174.5 0.2 1.2e-51 174.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) MAM33 PF02330.11 EEQ70100.1 - 9.9e-32 110.3 3.9 1.6e-30 106.4 2.7 2.0 1 1 0 1 1 1 1 Mitochondrial glycoprotein DNA_primase_S PF01896.14 EEQ70101.1 - 1.4e-52 177.3 0.0 2.3e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit MFS_1 PF07690.11 EEQ70102.1 - 2.2e-30 105.5 45.0 2.2e-30 105.5 31.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily DIOX_N PF14226.1 EEQ70103.1 - 2.6e-35 121.4 0.0 2.5e-33 115.0 0.0 2.3 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EEQ70103.1 - 0.015 15.5 0.0 0.032 14.5 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 EEQ70104.1 - 2.7e-08 33.3 4.5 0.0012 18.6 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat ORC6 PF05460.8 EEQ70104.1 - 3 6.8 12.3 6.3 5.8 8.5 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RNA_pol_N PF01194.12 EEQ70105.1 - 9.7e-31 105.5 1.6 1.1e-30 105.4 1.1 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 EEQ70105.1 - 0.062 13.4 0.9 0.12 12.4 0.6 1.5 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) CAP59_mtransfer PF11735.3 EEQ70107.1 - 1.4e-88 296.2 0.0 1.9e-88 295.7 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Suc_Fer-like PF06999.7 EEQ70108.1 - 3.6e-17 63.1 0.0 4.8e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Fungal_trans PF04082.13 EEQ70109.1 - 3.3e-16 58.9 0.8 3.3e-16 58.9 0.6 2.3 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ70109.1 - 6e-07 29.2 5.6 1.2e-06 28.3 3.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_18 PF12833.2 EEQ70109.1 - 0.032 14.3 0.1 0.12 12.4 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain TFIIA PF03153.8 EEQ70109.1 - 8.7 6.1 6.5 16 5.2 4.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit adh_short_C2 PF13561.1 EEQ70110.1 - 1.1e-23 84.2 0.4 1.4e-23 83.9 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEQ70110.1 - 7e-21 74.8 4.5 7e-21 74.8 3.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EEQ70110.1 - 3.5e-08 33.3 2.4 3.3e-07 30.1 1.6 2.0 1 1 0 1 1 1 1 KR domain HHH_5 PF14520.1 EEQ70110.1 - 0.0058 16.7 0.3 0.016 15.3 0.1 2.1 2 1 0 2 2 2 1 Helix-hairpin-helix domain SMC_N PF02463.14 EEQ70112.1 - 3.9e-78 261.6 0.0 9.3e-78 260.4 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EEQ70112.1 - 1.6e-28 99.1 0.1 7.6e-28 96.8 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EEQ70112.1 - 5.7e-12 46.2 6.3 2e-05 24.6 0.7 3.2 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EEQ70112.1 - 0.00055 19.4 0.0 0.0012 18.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain CRCB PF02537.10 EEQ70112.1 - 0.24 11.2 0.0 0.45 10.4 0.0 1.3 1 0 0 1 1 1 0 CrcB-like protein AAA_13 PF13166.1 EEQ70112.1 - 1.6 7.0 97.7 0.16 10.4 14.0 6.3 3 2 4 7 7 7 0 AAA domain Reo_sigmaC PF04582.7 EEQ70112.1 - 1.7 7.7 25.8 0.99 8.5 1.0 4.6 2 1 4 6 6 6 0 Reovirus sigma C capsid protein ELYS PF13934.1 EEQ70113.1 - 2e-76 256.7 0.4 2.4e-76 256.4 0.3 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly zf-CCCH PF00642.19 EEQ70114.1 - 0.00026 20.5 1.8 0.0005 19.6 1.2 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EEQ70114.1 - 0.26 11.3 2.2 0.55 10.3 1.5 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Ribosomal_S10 PF00338.17 EEQ70115.1 - 5.2e-28 96.7 0.6 6.2e-28 96.5 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CUE PF02845.11 EEQ70116.1 - 1.2e-08 34.2 0.1 3.6e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 CUE domain DUF3588 PF12140.3 EEQ70116.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3588) FA_desaturase PF00487.19 EEQ70117.1 - 1.1e-36 126.6 27.9 1.6e-36 126.0 19.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EEQ70117.1 - 1.2e-12 47.4 0.0 2.5e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Unstab_antitox PF09720.5 EEQ70117.1 - 0.015 14.9 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative addiction module component PGM_PMM_I PF02878.11 EEQ70118.1 - 9.2e-35 119.1 0.0 1.7e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EEQ70118.1 - 3.2e-26 91.6 0.0 8.5e-26 90.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EEQ70118.1 - 4.9e-11 42.6 0.0 4.4e-10 39.5 0.0 2.3 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EEQ70118.1 - 3e-09 36.7 0.0 8.4e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pyr_redox_dim PF02852.17 EEQ70119.1 - 4.8e-40 136.0 0.2 1.8e-39 134.1 0.2 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EEQ70119.1 - 3.4e-39 134.8 18.1 5.3e-38 130.9 9.0 4.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEQ70119.1 - 1.9e-21 76.2 12.2 1.3e-19 70.3 1.3 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEQ70119.1 - 4.7e-11 42.4 9.4 3.4e-10 39.5 0.1 3.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 EEQ70119.1 - 7.2e-10 38.2 9.6 8.8e-08 31.4 2.2 2.8 2 1 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EEQ70119.1 - 9e-10 38.9 1.2 1.8e-06 28.1 0.1 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEQ70119.1 - 2.8e-08 33.0 12.3 0.00026 20.0 0.1 3.3 3 0 0 3 3 3 3 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEQ70119.1 - 1e-07 31.1 11.7 2.3e-07 30.0 2.0 2.8 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 EEQ70119.1 - 1.4e-07 31.4 12.0 5.2e-05 23.2 0.4 3.0 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EEQ70119.1 - 7.4e-07 28.3 0.2 0.031 13.1 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 EEQ70119.1 - 1.8e-06 27.6 3.1 0.0022 17.5 0.1 3.1 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EEQ70119.1 - 0.00014 21.0 8.0 0.00019 20.6 0.1 2.7 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.9 EEQ70119.1 - 0.00018 20.1 1.6 0.00018 20.1 1.1 4.1 5 0 0 5 5 5 2 HI0933-like protein Lycopene_cycl PF05834.7 EEQ70119.1 - 0.0016 17.4 1.6 0.063 12.1 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EEQ70119.1 - 0.01 14.9 11.7 0.13 11.3 0.8 3.4 3 1 1 4 4 4 0 FAD binding domain NAD_binding_7 PF13241.1 EEQ70119.1 - 0.015 15.5 2.6 0.3 11.3 0.1 3.1 3 0 0 3 3 3 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.14 EEQ70119.1 - 0.031 13.3 3.7 0.43 9.6 0.1 3.6 3 1 0 4 4 4 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FMO-like PF00743.14 EEQ70119.1 - 0.088 10.9 0.7 0.26 9.4 0.1 1.9 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Amino_oxidase PF01593.19 EEQ70119.1 - 0.12 11.4 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 EEQ70119.1 - 0.6 8.6 6.9 0.76 8.3 0.3 2.3 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.13 EEQ70119.1 - 1.5 8.4 12.0 0.038 13.6 1.0 3.0 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.20 EEQ70120.1 - 2.1e-09 36.9 0.1 3.9e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ70120.1 - 0.02 13.9 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.18 EEQ70120.1 - 0.053 13.2 0.0 0.099 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RNase_T PF00929.19 EEQ70121.1 - 3.8e-12 46.7 0.1 2.2e-08 34.5 0.0 2.3 2 0 0 2 2 2 2 Exonuclease CHORD PF04968.7 EEQ70121.1 - 7.4e-05 22.9 0.9 0.0002 21.5 0.6 1.7 1 0 0 1 1 1 1 CHORD Entericidin PF08085.6 EEQ70121.1 - 0.12 12.1 0.4 0.4 10.5 0.0 2.1 2 0 0 2 2 2 0 Entericidin EcnA/B family Auts2 PF15336.1 EEQ70122.1 - 1.3 9.0 3.6 0.36 10.8 0.5 1.6 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein Sugar_tr PF00083.19 EEQ70125.1 - 7.5e-15 54.4 6.3 1.2e-10 40.5 2.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EEQ70125.1 - 1.2e-13 50.5 10.8 1.4e-12 47.0 3.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EEQ70125.1 - 0.035 12.2 0.8 0.05 11.7 0.6 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector MFS_2 PF13347.1 EEQ70125.1 - 0.072 11.4 3.2 0.75 8.1 0.5 2.1 2 0 0 2 2 2 0 MFS/sugar transport protein BTB PF00651.26 EEQ70126.1 - 0.014 15.3 0.1 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain ATP-sulfurylase PF01747.12 EEQ70126.1 - 0.076 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 ATP-sulfurylase F-box-like PF12937.2 EEQ70126.1 - 0.13 12.0 0.8 2.3 7.9 0.4 2.7 2 0 0 2 2 2 0 F-box-like FmdA_AmdA PF03069.10 EEQ70127.1 - 7e-157 521.8 0.0 8.1e-157 521.6 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family FAD_binding_4 PF01565.18 EEQ70128.1 - 0.00015 21.2 0.1 0.00029 20.3 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pro_isomerase PF00160.16 EEQ70129.1 - 1.5e-46 158.4 0.5 2.3e-46 157.8 0.3 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EEQ70129.1 - 1.3e-09 37.5 7.7 0.00024 20.7 0.2 2.3 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 EEQ70129.1 - 6.2e-06 25.7 7.0 3.4e-05 23.4 0.9 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ70129.1 - 0.00011 22.0 8.0 0.00088 19.1 3.6 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ70129.1 - 0.00025 20.4 0.8 0.00025 20.4 0.6 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ70129.1 - 0.00069 20.2 8.3 0.043 14.5 3.6 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ70129.1 - 0.046 14.3 5.3 0.13 12.9 1.7 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat Oxidored_nitro PF00148.14 EEQ70129.1 - 0.049 12.2 0.5 0.084 11.5 0.3 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase TPR_9 PF13371.1 EEQ70129.1 - 0.16 11.8 2.8 0.58 10.0 0.7 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ70129.1 - 0.25 11.6 1.7 2.6 8.4 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ70129.1 - 7.6 6.5 11.0 0.15 11.9 0.7 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Tyr_Deacylase PF02580.11 EEQ70130.1 - 3.4e-33 114.6 0.3 2e-17 63.4 0.0 2.1 1 1 1 2 2 2 2 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.10 EEQ70131.1 - 1.2e-97 325.7 15.5 1.9e-97 325.1 10.8 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EEQ70131.1 - 7.5e-43 145.6 12.0 2.3e-42 144.0 8.3 1.9 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Cep57_MT_bd PF06657.8 EEQ70131.1 - 0.0071 16.2 5.6 0.069 13.1 0.2 2.7 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 Poty_PP PF08440.5 EEQ70131.1 - 0.0081 15.2 0.9 0.0081 15.2 0.6 1.6 2 0 0 2 2 2 1 Potyviridae polyprotein DUF2373 PF10180.4 EEQ70131.1 - 0.013 15.0 3.5 0.028 13.9 2.4 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Mu-like_Pro PF10123.4 EEQ70131.1 - 0.54 9.6 8.9 0.14 11.6 3.7 1.8 2 0 0 2 2 2 0 Mu-like prophage I protein Syntaxin_2 PF14523.1 EEQ70131.1 - 0.6 10.1 6.9 0.13 12.3 1.8 2.1 2 0 0 2 2 2 0 Syntaxin-like protein Snapin_Pallidin PF14712.1 EEQ70131.1 - 0.8 10.0 6.1 4.9 7.5 0.2 2.5 2 0 0 2 2 2 0 Snapin/Pallidin DUF2951 PF11166.3 EEQ70131.1 - 5.5 6.9 7.7 0.96 9.3 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) zf-C2H2_4 PF13894.1 EEQ70133.1 - 1.8e-05 24.7 6.3 0.028 14.7 0.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ70133.1 - 0.00063 19.9 6.5 0.4 11.1 0.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type TFIIA PF03153.8 EEQ70133.1 - 2.1 8.1 10.2 2.2 8.0 7.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2215 PF10225.4 EEQ70133.1 - 3.7 6.9 6.9 2.5 7.4 1.5 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) Spc7_N PF15402.1 EEQ70133.1 - 6 4.7 14.3 7.4 4.4 9.9 1.2 1 1 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DNA_binding_1 PF01035.15 EEQ70134.1 - 9.3e-25 86.2 0.0 1.6e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain SnoaL PF07366.7 EEQ70135.1 - 7.5e-05 22.3 0.0 0.00038 20.0 0.0 2.1 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EEQ70135.1 - 0.0012 19.2 1.7 0.0014 19.0 0.1 1.9 3 0 0 3 3 3 1 SnoaL-like domain DLH PF01738.13 EEQ70135.1 - 0.007 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family UPF0546 PF10639.4 EEQ70136.1 - 2.9e-35 120.5 3.1 2.5e-34 117.4 2.2 1.9 1 1 0 1 1 1 1 Uncharacterised protein family UPF0546 EamA PF00892.15 EEQ70136.1 - 0.0015 18.5 3.7 0.0015 18.5 2.6 1.9 2 0 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 EEQ70136.1 - 0.59 10.3 8.5 0.043 14.0 2.5 1.7 2 1 0 2 2 2 0 Multidrug resistance efflux transporter Chitin_synth_1 PF01644.12 EEQ70137.1 - 2.1e-81 271.5 0.2 3e-81 271.0 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EEQ70137.1 - 3.3e-31 106.7 0.0 6.7e-31 105.8 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EEQ70137.1 - 1.4e-22 79.8 1.3 5e-18 64.7 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EEQ70137.1 - 1.1e-09 38.3 4.2 1.1e-09 38.3 2.9 3.1 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EEQ70137.1 - 4.2e-09 36.5 0.0 2.5e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Kdo PF06293.9 EEQ70138.1 - 7.1e-05 21.9 0.1 0.00016 20.8 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EEQ70138.1 - 0.0013 17.9 0.8 0.0071 15.5 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain Choline_kinase PF01633.15 EEQ70138.1 - 0.009 15.6 1.5 0.028 13.9 0.0 2.3 3 0 0 3 3 3 1 Choline/ethanolamine kinase APH PF01636.18 EEQ70138.1 - 0.028 14.1 0.3 0.028 14.1 0.2 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 EEQ70138.1 - 0.21 10.9 0.0 0.21 10.9 0.0 1.9 2 0 0 2 2 2 0 RIO1 family PEHE PF15275.1 EEQ70138.1 - 2.7 8.4 12.9 0.31 11.4 4.9 2.3 2 0 0 2 2 2 0 PEHE domain DUF4192 PF13830.1 EEQ70138.1 - 3.7 7.1 5.3 5.4 6.5 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) LMWPc PF01451.16 EEQ70139.1 - 2e-30 105.9 0.0 1e-26 93.8 0.0 2.2 2 0 0 2 2 2 2 Low molecular weight phosphotyrosine protein phosphatase COQ7 PF03232.8 EEQ70140.1 - 1.2e-62 210.4 0.3 1.9e-62 209.7 0.0 1.4 2 0 0 2 2 2 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 EEQ70140.1 - 0.0017 18.7 0.0 0.0039 17.5 0.0 1.6 1 1 0 1 1 1 1 Rubrerythrin TPIP1 PF15338.1 EEQ70140.1 - 0.057 13.2 0.1 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 p53-regulated apoptosis-inducing protein 1 Plus-3 PF03126.13 EEQ70141.1 - 7e-34 116.1 0.2 8.7e-33 112.6 0.0 2.6 3 0 0 3 3 3 1 Plus-3 domain MRC1 PF09444.5 EEQ70142.1 - 7.1e-33 113.9 15.8 7.1e-33 113.9 10.9 8.3 6 3 2 8 8 8 1 MRC1-like domain HAD_2 PF13419.1 EEQ70144.1 - 0.00074 19.7 0.2 1.4 9.0 0.0 2.8 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PqqD PF05402.7 EEQ70144.1 - 0.02 14.9 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) MIF4G PF02854.14 EEQ70145.1 - 9.5e-22 77.4 0.1 3.6e-21 75.5 0.1 2.0 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EEQ70145.1 - 2.8e-18 65.6 0.0 7.2e-18 64.3 0.0 1.8 1 0 0 1 1 1 1 MA3 domain Nop14 PF04147.7 EEQ70145.1 - 4.2 5.1 37.3 3.9e+03 -4.7 25.8 2.3 1 1 0 1 1 1 0 Nop14-like family SRP14 PF02290.10 EEQ70146.1 - 8e-23 80.1 0.0 1.1e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Inp1 PF12634.2 EEQ70147.1 - 1.1e-35 122.4 0.0 2.2e-35 121.4 0.0 1.5 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 EI24 PF07264.6 EEQ70148.1 - 1.5e-07 31.1 13.3 2e-05 24.1 9.2 2.3 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF3487 PF11990.3 EEQ70148.1 - 0.34 10.3 3.8 13 5.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) Pox_polyA_pol_N PF12630.2 EEQ70154.1 - 0.083 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain Phospho_p8 PF10195.4 EEQ70155.1 - 0.1 12.4 0.3 0.14 12.0 0.2 1.2 1 0 0 1 1 1 0 DNA-binding nuclear phosphoprotein p8 SLT PF01464.15 EEQ70156.1 - 0.0042 16.5 0.0 0.019 14.4 0.0 1.9 2 0 0 2 2 2 1 Transglycosylase SLT domain NAGidase PF07555.8 EEQ70157.1 - 5e-75 252.2 2.0 3.8e-48 163.9 0.6 2.2 1 1 1 2 2 2 2 beta-N-acetylglucosaminidase Glyco_hydro_20b PF02838.10 EEQ70157.1 - 1e-06 29.3 0.0 1.9e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Abhydrolase_6 PF12697.2 EEQ70161.1 - 8.8e-19 68.2 0.4 4.3e-11 43.1 0.2 2.0 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ70161.1 - 9.4e-08 31.9 0.0 1.5e-07 31.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Sulfate_transp PF00916.15 EEQ70162.1 - 2.5e-05 23.4 3.4 2.5e-05 23.4 2.4 2.8 2 1 1 3 3 3 1 Sulfate transporter family BenE PF03594.8 EEQ70162.1 - 0.012 14.1 16.6 0.15 10.5 0.1 2.8 3 1 0 3 3 3 0 Benzoate membrane transport protein DUF1418 PF07214.7 EEQ70162.1 - 9.9 5.8 7.5 1.1 8.8 0.9 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1418) PhyH PF05721.8 EEQ70163.1 - 1.5e-40 139.4 0.0 2.9e-40 138.5 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) UTP15_C PF09384.5 EEQ70164.1 - 9.4e-53 177.8 0.1 6.1e-52 175.2 0.0 2.1 1 1 1 2 2 2 1 UTP15 C terminal WD40 PF00400.27 EEQ70164.1 - 7.3e-29 98.5 1.4 1.4e-08 34.2 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EEQ70164.1 - 0.0069 15.8 0.6 0.28 10.5 0.1 2.5 1 1 1 2 2 2 1 PQQ-like domain Nbas_N PF15492.1 EEQ70164.1 - 0.056 12.5 0.0 0.14 11.1 0.0 1.6 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal L31 PF09784.4 EEQ70164.1 - 8.9 6.4 7.2 4.7 7.3 2.7 2.3 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 C2 PF00168.25 EEQ70165.1 - 1.7e-12 46.9 0.1 3.1e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain TAP42 PF04177.7 EEQ70167.1 - 0.047 12.6 0.0 0.06 12.2 0.0 1.1 1 0 0 1 1 1 0 TAP42-like family AAA_12 PF13087.1 EEQ70168.1 - 1.2e-28 99.8 0.0 2.3e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEQ70168.1 - 1.8e-21 76.7 0.1 2.3e-12 47.0 0.0 2.5 1 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EEQ70168.1 - 1.7e-09 37.2 0.0 7.4e-09 35.2 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain UvrD-helicase PF00580.16 EEQ70168.1 - 8.1e-05 22.0 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 EEQ70168.1 - 9.1e-05 22.0 0.0 0.29 10.6 0.0 3.9 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EEQ70168.1 - 0.0011 18.8 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EEQ70168.1 - 0.0016 18.0 0.0 0.0065 16.0 0.0 2.0 3 0 0 3 3 3 1 AAA domain UvrD_C PF13361.1 EEQ70168.1 - 0.019 14.4 0.0 1.4 8.3 0.0 2.8 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.9 EEQ70168.1 - 0.02 14.5 0.0 0.16 11.6 0.0 2.2 1 1 0 1 1 1 0 Helicase Herpes_UL16 PF03044.9 EEQ70168.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL16/UL94 family Isochorismatase PF00857.15 EEQ70170.1 - 2.2e-27 96.1 0.0 8.6e-22 77.8 0.0 2.4 1 1 1 2 2 2 2 Isochorismatase family GST_N_3 PF13417.1 EEQ70170.1 - 1.7e-12 47.3 0.1 5.3e-12 45.7 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEQ70170.1 - 2.3e-10 40.3 0.1 9.8e-10 38.3 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EEQ70170.1 - 1.9e-08 34.3 0.0 4.6e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEQ70170.1 - 2.1e-05 24.2 0.5 5.3e-05 23.0 0.4 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEQ70170.1 - 0.00034 21.0 0.0 0.00085 19.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EEQ70170.1 - 0.0032 17.4 0.0 0.0076 16.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_L22 PF00237.14 EEQ70171.1 - 1.4e-15 57.1 0.7 1.9e-07 30.9 0.1 2.5 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e RRM_1 PF00076.17 EEQ70172.1 - 1.1e-40 137.0 0.0 4.7e-18 64.5 0.0 4.2 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ70172.1 - 1.5e-34 117.7 0.0 8.7e-16 57.6 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ70172.1 - 3.8e-18 65.0 0.0 8.5e-07 28.7 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEQ70172.1 - 0.00073 19.2 0.0 0.0089 15.7 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.6 EEQ70172.1 - 0.0027 17.0 0.2 0.0068 15.7 0.1 1.7 1 0 0 1 1 1 1 Lsm interaction motif TPR_14 PF13428.1 EEQ70172.1 - 0.021 15.4 4.7 0.36 11.5 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat NPHI_C PF08469.5 EEQ70172.1 - 0.096 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Nucleoside triphosphatase I C-terminal L_HGMIC_fpl PF10242.4 EEQ70174.1 - 1.9e-05 24.7 3.0 1.9e-05 24.7 2.1 1.7 2 0 0 2 2 2 1 Lipoma HMGIC fusion partner-like protein DUF2339 PF10101.4 EEQ70174.1 - 0.00047 18.6 2.7 0.00063 18.1 1.9 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) Frag1 PF10277.4 EEQ70174.1 - 1.6 8.1 8.0 6 6.2 5.4 2.1 1 1 0 1 1 1 0 Frag1/DRAM/Sfk1 family Clc-like PF07062.7 EEQ70174.1 - 6.4 5.9 9.6 1.3e+02 1.6 6.6 2.5 1 1 0 1 1 1 0 Clc-like His_Phos_1 PF00300.17 EEQ70175.1 - 1.9e-17 63.7 0.0 2.9e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ComA PF02679.10 EEQ70177.1 - 8e-82 273.9 0.0 9.6e-82 273.6 0.0 1.1 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) AP_endonuc_2 PF01261.19 EEQ70177.1 - 0.0083 15.4 0.0 0.018 14.3 0.0 1.7 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel MARVEL PF01284.18 EEQ70183.1 - 9.2e-31 106.6 9.7 1e-30 106.4 6.7 1.0 1 0 0 1 1 1 1 Membrane-associating domain MFS_1 PF07690.11 EEQ70183.1 - 0.0003 19.6 5.5 0.00039 19.2 3.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MtN3_slv PF03083.11 EEQ70183.1 - 6.5 6.6 8.1 22 5.0 2.5 2.4 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Pkinase PF00069.20 EEQ70184.1 - 1.6e-58 197.8 0.1 1.2e-54 185.1 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ70184.1 - 1.4e-25 89.8 0.0 4e-24 85.0 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase UBA_2 PF08587.6 EEQ70184.1 - 3.2e-07 30.4 0.0 6.3e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EEQ70184.1 - 4.2e-06 25.9 0.0 1.6e-05 24.0 0.0 1.8 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EEQ70184.1 - 0.0013 18.1 0.1 0.0024 17.2 0.1 1.4 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 EEQ70184.1 - 0.0096 14.5 0.0 0.016 13.8 0.0 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.9 EEQ70184.1 - 0.033 13.2 0.1 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ70184.1 - 0.033 13.9 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family PsaA_PsaB PF00223.14 EEQ70184.1 - 0.14 10.2 0.0 0.19 9.8 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein Seadorna_VP7 PF07387.6 EEQ70184.1 - 0.19 10.5 0.1 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EEQ70184.1 - 0.23 10.2 0.2 0.36 9.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PRELI PF04707.9 EEQ70185.1 - 3.5e-24 85.1 0.0 2.1e-21 76.1 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family DUF2933 PF11666.3 EEQ70185.1 - 0.078 12.5 3.5 0.17 11.4 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) WD40 PF00400.27 EEQ70187.1 - 5.4e-18 64.1 11.3 8.2e-07 28.6 0.1 8.4 7 1 1 8 8 8 4 WD domain, G-beta repeat NACHT PF05729.7 EEQ70187.1 - 5.1e-07 29.4 0.1 1.6e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EEQ70187.1 - 6e-07 29.6 0.0 2.3e-06 27.7 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain SGL PF08450.7 EEQ70187.1 - 0.023 14.0 0.0 0.39 10.0 0.0 2.7 2 1 2 4 4 4 0 SMP-30/Gluconolaconase/LRE-like region APS_kinase PF01583.15 EEQ70187.1 - 0.036 13.7 0.2 0.068 12.8 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Coatomer_WDAD PF04053.9 EEQ70187.1 - 0.046 12.5 0.0 0.62 8.8 0.0 2.3 2 0 0 2 2 2 0 Coatomer WD associated region PIF1 PF05970.9 EEQ70187.1 - 0.05 12.5 0.0 0.083 11.8 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_17 PF13207.1 EEQ70187.1 - 0.078 13.7 0.0 0.4 11.5 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EEQ70187.1 - 0.079 13.1 0.0 0.27 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain PD40 PF07676.7 EEQ70187.1 - 0.084 12.5 0.3 94 2.8 0.0 3.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat NB-ARC PF00931.17 EEQ70187.1 - 0.094 11.5 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.24 EEQ70187.1 - 0.11 12.6 0.1 0.4 10.8 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MgtC PF02308.11 EEQ70187.1 - 0.15 11.9 0.1 0.3 10.9 0.1 1.4 1 0 0 1 1 1 0 MgtC family AAA_30 PF13604.1 EEQ70187.1 - 0.18 11.3 0.1 0.4 10.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain UQ_con PF00179.21 EEQ70188.1 - 3.7e-30 104.2 0.0 4.5e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EEQ70188.1 - 0.093 12.6 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 RWD domain Chitin_synth_1 PF01644.12 EEQ70189.1 - 2.4e-69 232.2 0.0 3.5e-69 231.7 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EEQ70189.1 - 6e-28 96.3 0.0 1.2e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EEQ70189.1 - 1.8e-25 89.3 0.0 4.3e-20 71.6 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EEQ70189.1 - 1.5e-11 44.3 0.3 1.5e-11 44.3 0.2 2.9 4 1 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EEQ70189.1 - 4.5e-08 33.1 0.0 2.2e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 HRXXH PF13933.1 EEQ70190.1 - 2.6e-102 341.4 0.3 3e-102 341.2 0.2 1.0 1 0 0 1 1 1 1 Putative peptidase family Lamp PF01299.12 EEQ70190.1 - 0.51 9.4 3.9 0.7 8.9 2.7 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Aminotran_4 PF01063.14 EEQ70191.1 - 1.2e-27 96.9 0.0 2.7e-27 95.7 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class IV TAF8_C PF10406.4 EEQ70193.1 - 1.9e-23 82.2 1.3 5.9e-23 80.6 0.9 1.9 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 EEQ70193.1 - 9.2e-06 25.3 0.0 2.2e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Bromodomain associated Mitochondr_Som1 PF11093.3 EEQ70194.1 - 3.7e-08 33.0 0.0 4.8e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 PALP PF00291.20 EEQ70196.1 - 2.1e-66 224.2 2.5 3.7e-66 223.4 1.7 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme IlvC PF01450.14 EEQ70197.1 - 1.3e-31 109.4 0.0 1.3e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2OG-FeII_Oxy_2 PF13532.1 EEQ70198.1 - 5.6e-23 81.7 0.0 5.6e-23 81.7 0.0 2.7 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.15 EEQ70198.1 - 1.3e-20 74.0 0.0 2e-13 50.6 0.0 2.5 2 0 0 2 2 2 2 Isochorismatase family GST_C PF00043.20 EEQ70198.1 - 0.00061 19.7 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEQ70198.1 - 0.0058 17.0 0.0 0.016 15.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Suf PF05843.9 EEQ70198.1 - 0.17 11.5 15.7 0.094 12.4 3.4 2.7 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) ECH PF00378.15 EEQ70199.1 - 2.1e-31 108.9 0.0 4.5e-31 107.8 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Methyltrn_RNA_4 PF09936.4 EEQ70199.1 - 0.05 13.1 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase UPF0506 PF11703.3 EEQ70199.1 - 0.14 12.1 0.1 0.25 11.3 0.1 1.3 1 0 0 1 1 1 0 UPF0506 Phage_lysis PF03245.8 EEQ70200.1 - 0.12 12.3 1.1 0.24 11.3 0.7 1.5 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein zf-Di19 PF05605.7 EEQ70201.1 - 0.057 13.5 1.7 13 6.0 0.1 2.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 EEQ70201.1 - 8.5 6.9 17.8 0.47 10.9 1.1 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger RNA_pol_Rpb1_5 PF04998.12 EEQ70202.1 - 8.3e-89 297.5 0.9 1.5e-88 296.6 0.6 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EEQ70202.1 - 5.2e-84 282.3 0.0 7.8e-84 281.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EEQ70202.1 - 3.6e-67 225.4 0.1 7.4e-67 224.4 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EEQ70202.1 - 3e-35 121.2 0.0 8.3e-35 119.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EEQ70202.1 - 5.3e-28 96.9 0.0 1.4e-27 95.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 GTP_EFTU PF00009.22 EEQ70203.1 - 9.8e-49 165.3 0.0 1.5e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EEQ70203.1 - 2.2e-37 127.2 5.2 3.8e-37 126.5 3.6 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EEQ70203.1 - 1.6e-18 66.3 0.0 2.9e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 EEQ70203.1 - 4e-05 23.5 0.0 9.8e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EEQ70203.1 - 0.00024 20.5 0.0 0.00048 19.5 0.0 1.5 1 0 0 1 1 1 1 Ras family GTP_EFTU_D2 PF03144.20 EEQ70203.1 - 0.00025 21.0 0.1 0.0006 19.8 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EEQ70203.1 - 0.0051 16.6 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 EEQ70203.1 - 0.028 13.6 0.0 0.06 12.5 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit HORMA PF02301.13 EEQ70204.1 - 4.4e-50 170.0 0.1 5.1e-50 169.8 0.1 1.0 1 0 0 1 1 1 1 HORMA domain Alba PF01918.16 EEQ70204.1 - 0.097 12.2 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Alba TauE PF01925.14 EEQ70205.1 - 0.076 12.4 0.1 0.44 9.9 0.0 1.9 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE Sec1 PF00995.18 EEQ70207.1 - 4.6e-151 504.2 0.0 5.4e-151 504.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family zf-CCCH PF00642.19 EEQ70208.1 - 0.0025 17.4 0.5 0.0041 16.7 0.3 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Mitoc_L55 PF09776.4 EEQ70208.1 - 0.86 9.2 4.1 4.6 6.8 0.1 2.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L55 GRP PF07172.6 EEQ70208.1 - 4.1 7.9 13.4 11 6.5 9.3 1.7 1 0 0 1 1 1 0 Glycine rich protein family FHA PF00498.21 EEQ70209.1 - 5.3e-10 39.2 0.0 1.2e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain TPR_11 PF13414.1 EEQ70210.1 - 1.6e-56 187.8 40.6 1.4e-11 43.9 0.9 7.6 2 2 8 10 10 10 10 TPR repeat TPR_1 PF00515.23 EEQ70210.1 - 6e-38 126.9 28.6 5.5e-06 25.7 0.0 11.5 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ70210.1 - 3.3e-37 123.4 25.6 0.00012 21.6 0.3 11.5 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ70210.1 - 2.7e-25 88.1 19.9 1.5e-06 28.0 0.5 7.2 3 1 5 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ70210.1 - 1.5e-24 86.0 26.0 4.3e-08 33.6 0.8 7.1 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ70210.1 - 3.8e-18 64.1 13.6 0.011 15.8 0.0 9.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ70210.1 - 1.4e-15 55.7 16.1 0.052 13.3 0.0 10.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ70210.1 - 9.5e-13 46.9 16.9 0.11 12.3 0.2 9.7 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ70210.1 - 1e-12 48.2 18.9 3.4e-06 27.2 0.3 6.9 4 2 1 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ70210.1 - 2.2e-12 46.6 14.2 3.8e-07 29.8 0.8 6.7 3 2 5 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ70210.1 - 3.3e-12 45.8 20.5 0.023 15.2 0.5 9.9 4 3 6 10 10 10 4 Tetratricopeptide repeat Apc3 PF12895.2 EEQ70210.1 - 7.9e-12 45.1 17.5 0.0032 17.5 0.3 5.5 3 1 3 6 6 6 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EEQ70210.1 - 0.00043 20.5 18.5 7 7.3 0.1 8.8 9 0 0 9 9 8 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 EEQ70210.1 - 0.0039 16.3 8.6 17 4.7 0.0 6.1 6 0 0 6 6 6 0 SHNi-TPR DUF3856 PF12968.2 EEQ70210.1 - 0.0048 16.7 4.1 1.4 8.7 0.0 4.6 4 2 0 4 4 4 1 Domain of Unknown Function (DUF3856) DUF3808 PF10300.4 EEQ70210.1 - 0.01 14.4 1.0 0.34 9.4 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3808) PPR PF01535.15 EEQ70210.1 - 0.014 15.3 0.1 16 5.7 0.0 4.2 3 0 0 3 3 3 0 PPR repeat TPR_10 PF13374.1 EEQ70210.1 - 0.089 12.7 13.8 2.6 8.0 0.3 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat MAS20 PF02064.10 EEQ70210.1 - 0.1 12.5 2.3 17 5.3 0.1 3.8 3 1 1 4 4 4 0 MAS20 protein import receptor TPR_4 PF07721.9 EEQ70210.1 - 1.6 9.3 13.7 50 4.7 0.1 6.6 8 0 0 8 8 5 0 Tetratricopeptide repeat DUF3723 PF12520.3 EEQ70211.1 - 2e-70 237.7 10.5 6.3e-56 189.9 0.9 4.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3723) DUF3052 PF11253.3 EEQ70211.1 - 0.046 13.3 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) DUF966 PF06136.8 EEQ70211.1 - 7.2 5.9 10.8 14 4.9 7.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Pkinase PF00069.20 EEQ70214.1 - 2.6e-07 30.0 0.0 2.8e-06 26.6 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ70214.1 - 1.7e-05 24.0 0.0 3.5e-05 23.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 EEQ70214.1 - 0.044 12.8 0.0 2.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PhyH PF05721.8 EEQ70215.1 - 3.4e-20 72.9 0.6 1.3e-15 58.0 0.3 2.1 1 1 1 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) RTA1 PF04479.8 EEQ70216.1 - 5.5e-44 150.3 12.9 7.9e-44 149.8 8.9 1.2 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.13 EEQ70217.1 - 3.5e-06 26.8 15.4 5.8e-06 26.1 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEQ70217.1 - 0.028 13.0 0.6 0.052 12.1 0.4 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain BLVR PF06375.6 EEQ70218.1 - 1.1 9.1 12.4 1.3 8.8 8.6 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Peptidase_S49_N PF08496.5 EEQ70218.1 - 2.4 7.9 8.4 1.2 8.9 4.6 1.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal OAD_gamma PF04277.8 EEQ70218.1 - 4.5 7.7 5.3 8.8 6.7 3.7 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain PHO4 PF01384.15 EEQ70219.1 - 4.5e-110 367.3 12.0 5.2e-110 367.1 8.3 1.0 1 0 0 1 1 1 1 Phosphate transporter family Tbf5 PF06331.7 EEQ70220.1 - 8.3e-27 92.7 0.7 9.2e-27 92.6 0.5 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DUF1325 PF07039.6 EEQ70220.1 - 0.086 12.4 0.2 0.088 12.4 0.1 1.1 1 0 0 1 1 1 0 SGF29 tudor-like domain EABR PF12180.3 EEQ70220.1 - 0.092 12.1 0.4 0.25 10.7 0.3 1.7 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 Glyoxalase_2 PF12681.2 EEQ70222.1 - 1.2e-09 38.7 0.0 1.5e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EEQ70222.1 - 0.00047 20.1 0.1 0.0041 17.1 0.1 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Opy2 PF09463.5 EEQ70223.1 - 1.1e-10 41.4 21.5 1.9e-10 40.6 14.9 1.4 1 0 0 1 1 1 1 Opy2 protein EphA2_TM PF14575.1 EEQ70223.1 - 0.0094 16.3 0.0 0.0094 16.3 0.0 1.8 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 EEQ70223.1 - 0.087 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain DUF1049 PF06305.6 EEQ70223.1 - 0.11 11.9 0.9 0.28 10.7 0.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1049) Kinocilin PF15033.1 EEQ70223.1 - 0.11 12.0 1.0 0.27 10.7 0.7 1.6 1 0 0 1 1 1 0 Kinocilin protein Adeno_E3_CR2 PF02439.10 EEQ70223.1 - 0.15 11.6 0.1 0.42 10.1 0.1 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Phage_Coat_B PF05356.6 EEQ70223.1 - 0.22 11.2 2.9 1.7 8.3 0.2 2.6 2 0 0 2 2 2 0 Phage Coat protein B MSG PF02349.10 EEQ70224.1 - 1.7 8.6 10.9 0.23 11.4 4.7 1.7 2 0 0 2 2 2 0 Major surface glycoprotein MgtE PF01769.11 EEQ70225.1 - 0.064 13.5 0.1 0.091 13.0 0.1 1.2 1 0 0 1 1 1 0 Divalent cation transporter Pkinase PF00069.20 EEQ70227.1 - 3.6e-09 36.1 0.0 8e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EEQ70227.1 - 8e-06 25.7 0.0 8e-06 25.7 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ70227.1 - 0.00036 19.6 0.1 0.0007 18.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HSDR_N_2 PF13588.1 EEQ70227.1 - 0.0013 18.5 0.1 0.13 12.0 0.0 2.5 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) Pkinase_Tyr PF07714.12 EEQ70227.1 - 0.0051 15.9 0.0 0.0085 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EEQ70227.1 - 0.043 13.3 0.0 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Ribosomal_L38e PF01781.13 EEQ70227.1 - 0.083 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal L38e protein family FAD_binding_3 PF01494.14 EEQ70228.1 - 2.5e-17 62.9 0.0 4.4e-14 52.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EEQ70228.1 - 7.4e-05 22.6 1.1 0.00018 21.4 0.8 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEQ70228.1 - 0.0097 15.8 0.1 0.014 15.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEQ70228.1 - 0.011 15.5 2.1 1.3 8.7 0.1 3.0 4 0 0 4 4 4 0 FAD-NAD(P)-binding SE PF08491.5 EEQ70228.1 - 0.026 13.3 0.0 0.06 12.1 0.0 1.5 2 0 0 2 2 2 0 Squalene epoxidase Thi4 PF01946.12 EEQ70228.1 - 0.037 13.1 0.1 0.062 12.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 EEQ70228.1 - 0.04 12.8 0.7 0.77 8.6 0.3 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EEQ70228.1 - 0.058 12.2 0.4 0.099 11.4 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 EEQ70228.1 - 0.058 12.2 1.4 0.12 11.2 1.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase F420_oxidored PF03807.12 EEQ70228.1 - 0.16 12.4 0.4 1.4 9.4 0.5 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_3 PF13738.1 EEQ70228.1 - 0.19 11.7 0.5 0.34 10.9 0.3 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 EEQ70229.1 - 1.9e-18 66.2 0.2 3.5e-18 65.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ70229.1 - 3.3e-06 26.8 12.5 5.9e-06 26.0 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zip PF02535.17 EEQ70231.1 - 6.2e-41 140.4 14.3 8.8e-41 139.9 9.9 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter HupE_UreJ PF04955.7 EEQ70231.1 - 0.0022 17.3 6.9 0.0022 17.3 4.8 2.4 2 0 0 2 2 2 1 HupE / UreJ protein Ras PF00071.17 EEQ70232.1 - 2.7e-49 166.6 0.0 3.2e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ70232.1 - 2.1e-15 57.2 0.0 3.9e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ70232.1 - 7.2e-11 41.6 0.0 9.6e-11 41.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EEQ70232.1 - 0.00031 20.8 0.1 0.0019 18.3 0.1 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 EEQ70232.1 - 0.00066 18.8 0.0 0.00081 18.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EEQ70232.1 - 0.0055 15.4 1.2 0.63 8.6 0.0 2.8 2 1 1 3 3 3 1 G-protein alpha subunit Pox_A32 PF04665.7 EEQ70232.1 - 0.026 13.8 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 EEQ70232.1 - 0.062 13.4 0.1 0.16 12.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EEQ70232.1 - 0.074 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EEQ70232.1 - 0.075 12.6 0.1 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 EEQ70232.1 - 0.12 12.2 0.0 0.59 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain PDZ_2 PF13180.1 EEQ70233.1 - 9.7e-08 31.7 0.3 1.8e-07 30.9 0.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EEQ70233.1 - 3.2e-07 30.4 0.2 8.9e-07 29.0 0.2 1.7 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) GRASP55_65 PF04495.9 EEQ70233.1 - 1.8e-06 27.9 0.0 2.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain DUF1192 PF06698.6 EEQ70233.1 - 0.078 12.7 0.2 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) RhoGEF PF00621.15 EEQ70234.1 - 6.7e-17 61.9 0.2 2e-16 60.3 0.1 1.8 1 1 0 1 1 1 1 RhoGEF domain SBDS PF01172.13 EEQ70235.1 - 2.7e-24 84.7 0.1 3.3e-24 84.4 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein VOMI PF03762.12 EEQ70235.1 - 0.025 14.5 0.0 0.025 14.5 0.0 1.1 1 0 0 1 1 1 0 Vitelline membrane outer layer protein I (VOMI) DUF3753 PF12575.3 EEQ70235.1 - 0.037 13.8 0.1 0.052 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) XkdN PF08890.6 EEQ70235.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 2 0 0 2 2 2 0 Phage XkdN-like protein FAD_binding_8 PF08022.7 EEQ70237.1 - 8.2e-23 80.2 0.0 1.6e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EEQ70237.1 - 7.8e-21 74.6 0.0 1.3e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EEQ70237.1 - 4.4e-15 55.8 9.0 4.4e-15 55.8 6.2 1.8 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EEQ70237.1 - 0.0064 16.5 0.0 0.017 15.2 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EEQ70237.1 - 0.058 13.9 0.0 2.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain 7TMR-DISM_7TM PF07695.6 EEQ70239.1 - 0.12 12.0 3.5 0.15 11.7 2.5 1.3 1 0 0 1 1 1 0 7TM diverse intracellular signalling UDG PF03167.14 EEQ70240.1 - 5.5e-19 68.1 0.0 9.3e-19 67.3 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily NRDE-2 PF08424.5 EEQ70241.1 - 2.6e-89 299.3 0.0 4.8e-89 298.4 0.0 1.5 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference DUF4388 PF14332.1 EEQ70241.1 - 0.014 15.2 0.2 5.4 6.9 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4388) TPR_14 PF13428.1 EEQ70241.1 - 0.023 15.2 7.6 32 5.5 0.1 6.2 6 1 0 6 6 6 0 Tetratricopeptide repeat BP28CT PF08146.7 EEQ70242.1 - 7.6e-44 149.1 0.1 1.2e-42 145.2 0.0 2.8 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EEQ70242.1 - 5.5e-26 90.8 9.0 6.3e-26 90.7 0.5 5.0 6 0 0 6 6 6 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 EEQ70242.1 - 9.7e-10 38.6 12.6 8.2e-05 22.8 0.0 7.0 8 0 0 8 8 8 3 HEAT repeats HEAT PF02985.17 EEQ70242.1 - 9e-05 22.2 9.8 0.0024 17.8 0.0 6.7 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 EEQ70242.1 - 2.2 8.8 18.2 3 8.4 0.3 7.4 6 1 1 7 7 7 0 HEAT-like repeat CN_hydrolase PF00795.17 EEQ70243.1 - 3.6e-21 75.3 0.0 6.6e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CPSF_A PF03178.10 EEQ70245.1 - 7.8e-104 347.2 0.0 1e-101 340.2 0.0 3.0 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 EEQ70245.1 - 1.1e-70 238.2 0.0 1.9e-70 237.4 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 EEQ70245.1 - 0.15 11.9 0.5 0.79 9.7 0.1 2.5 3 0 0 3 3 3 0 WD domain, G-beta repeat ubiquitin PF00240.18 EEQ70246.1 - 1.5e-16 59.5 0.0 2.7e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EEQ70246.1 - 5.4e-09 35.6 0.1 5.4e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 EEQ70246.1 - 1.1e-05 24.9 0.0 1.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EEQ70246.1 - 0.00079 19.5 0.0 0.0019 18.3 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EEQ70246.1 - 0.0078 16.0 1.3 0.008 16.0 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 EEQ70246.1 - 0.06 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD DUF4267 PF14087.1 EEQ70247.1 - 0.0029 17.1 1.1 0.0053 16.3 0.8 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4267) EMP70 PF02990.11 EEQ70248.1 - 2.4e-153 511.3 1.0 1e-152 509.2 0.7 1.9 1 1 0 1 1 1 1 Endomembrane protein 70 DUF3169 PF11368.3 EEQ70248.1 - 6.1 5.9 8.4 4.4 6.4 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) DER1 PF04511.10 EEQ70249.1 - 2e-48 164.5 1.4 2.3e-48 164.3 1.0 1.0 1 0 0 1 1 1 1 Der1-like family Serpentine_r_xa PF03383.10 EEQ70249.1 - 0.074 12.8 1.3 0.11 12.2 0.9 1.2 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa Histone PF00125.19 EEQ70250.1 - 1.6e-28 98.6 0.1 2.2e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EEQ70250.1 - 0.00025 21.1 0.1 0.00039 20.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EEQ70250.1 - 0.018 15.0 0.6 0.033 14.2 0.4 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EEQ70250.1 - 0.03 13.5 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Cohesin_load PF10345.4 EEQ70251.1 - 3.2e-185 616.8 4.4 4.1e-185 616.5 3.1 1.0 1 0 0 1 1 1 1 Cohesin loading factor RPN7 PF10602.4 EEQ70251.1 - 0.028 13.8 0.1 0.18 11.1 0.0 2.1 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Lactamase_B_4 PF13691.1 EEQ70251.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 tRNase Z endonuclease DUF2372 PF10178.4 EEQ70252.1 - 0.00045 20.2 0.0 0.00095 19.2 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) HA2 PF04408.18 EEQ70253.1 - 6.1e-20 71.1 0.0 1.9e-19 69.5 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEQ70253.1 - 7.2e-15 54.6 0.0 4.3e-14 52.1 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EEQ70253.1 - 6e-11 42.1 0.0 1.7e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EEQ70253.1 - 3.3e-09 36.4 0.0 5.2e-08 32.5 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EEQ70253.1 - 1e-05 25.4 3.2 0.062 13.1 0.0 3.3 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EEQ70253.1 - 0.00074 19.6 0.3 0.0049 16.9 0.0 2.5 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 EEQ70253.1 - 0.028 13.8 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 EEQ70253.1 - 0.042 12.7 0.0 0.088 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 EEQ70253.1 - 0.082 12.5 0.7 0.41 10.3 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase AAA_23 PF13476.1 EEQ70253.1 - 0.089 13.1 0.0 0.089 13.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain cwf21 PF08312.7 EEQ70254.1 - 3.6e-16 58.7 10.2 3.6e-16 58.7 7.1 1.8 2 0 0 2 2 2 1 cwf21 domain DUF3650 PF12368.3 EEQ70254.1 - 0.16 11.5 0.1 0.16 11.5 0.1 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3650) Phosphodiest PF01663.17 EEQ70255.1 - 1.8e-11 43.9 1.1 4.1e-11 42.8 0.8 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EEQ70255.1 - 8.4e-06 25.3 1.1 1.4e-05 24.6 0.7 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EEQ70255.1 - 2.5e-05 23.6 0.1 3.8e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Ctr PF04145.10 EEQ70255.1 - 0.012 15.6 0.1 0.047 13.7 0.1 2.0 1 0 0 1 1 1 0 Ctr copper transporter family TPR_20 PF14561.1 EEQ70256.1 - 0.014 15.4 0.9 0.025 14.6 0.6 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat RNase_H2-Ydr279 PF09468.5 EEQ70256.1 - 0.21 10.7 9.2 0.25 10.5 6.4 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Spot_14 PF07084.7 EEQ70256.1 - 0.39 10.5 5.3 0.06 13.2 1.1 1.5 1 1 1 2 2 2 0 Thyroid hormone-inducible hepatic protein Spot 14 GIDA_assoc_3 PF13932.1 EEQ70256.1 - 9.7 6.3 6.9 0.31 11.1 0.6 1.7 2 1 0 2 2 2 0 GidA associated domain 3 DUF755 PF05501.6 EEQ70257.1 - 0.012 15.6 1.9 0.018 15.1 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) FRQ PF09421.5 EEQ70257.1 - 0.02 12.7 3.0 0.026 12.3 2.1 1.1 1 0 0 1 1 1 0 Frequency clock protein BatA PF07584.6 EEQ70257.1 - 0.041 14.0 0.2 0.071 13.3 0.1 1.4 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal TAP35_44 PF07265.6 EEQ70257.1 - 0.056 13.1 0.3 0.1 12.3 0.1 1.5 1 1 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 DUF2217 PF10265.4 EEQ70257.1 - 0.057 12.1 0.4 0.071 11.8 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) IncA PF04156.9 EEQ70257.1 - 0.07 12.7 0.2 0.088 12.3 0.1 1.2 1 0 0 1 1 1 0 IncA protein DUF912 PF06024.7 EEQ70257.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CIAPIN1 PF05093.8 EEQ70258.1 - 0.085 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Pkinase PF00069.20 EEQ70259.1 - 3.4e-06 26.4 0.0 4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EEQ70259.1 - 0.00099 18.2 0.1 0.0015 17.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ70259.1 - 0.019 14.7 0.1 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Apolipoprotein PF01442.13 EEQ70260.1 - 0.0016 18.0 0.4 0.0031 17.0 0.2 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF3618 PF12277.3 EEQ70260.1 - 0.059 13.4 0.5 0.12 12.3 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) F-box-like PF12937.2 EEQ70261.1 - 0.00028 20.5 0.4 0.00076 19.1 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ70261.1 - 0.0017 17.9 0.4 0.005 16.4 0.3 1.8 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 EEQ70261.1 - 0.006 16.5 0.0 0.04 13.8 0.0 2.1 2 0 0 2 2 2 1 PRANC domain DUF2560 PF10834.3 EEQ70262.1 - 0.084 12.8 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2560) PUF PF00806.14 EEQ70263.1 - 5.2e-59 192.5 7.1 7.5e-09 34.5 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF260 PF03195.9 EEQ70263.1 - 0.016 15.4 0.2 4.3 7.6 0.1 3.2 2 1 0 2 2 2 0 Protein of unknown function DUF260 DUF3384 PF11864.3 EEQ70264.1 - 4.9e-92 308.8 0.6 4.9e-92 308.8 0.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 EEQ70264.1 - 1.6e-54 184.1 0.1 4.6e-54 182.6 0.1 1.8 2 0 0 2 2 2 1 Rap/ran-GAP Tuberin PF03542.11 EEQ70264.1 - 1.6e-31 109.7 0.2 1.3e-28 100.1 0.0 3.2 3 0 0 3 3 3 2 Tuberin CAS_CSE1 PF03378.10 EEQ70265.1 - 2e-187 622.8 0.1 1.4e-186 620.0 0.0 2.2 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EEQ70265.1 - 3.8e-156 519.2 4.6 3.8e-156 519.2 3.2 1.5 2 0 0 2 2 2 1 Cse1 IBN_N PF03810.14 EEQ70265.1 - 1.1e-13 50.8 0.0 1.1e-12 47.6 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EEQ70265.1 - 0.016 15.1 0.8 0.46 10.3 0.0 3.8 4 0 0 4 4 4 0 Exportin 1-like protein Cys_Met_Meta_PP PF01053.15 EEQ70266.1 - 2.1e-57 194.1 0.0 5.7e-57 192.7 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EEQ70266.1 - 6e-05 22.1 0.0 0.00013 21.0 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EEQ70266.1 - 0.001 17.9 0.0 0.0025 16.6 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EEQ70266.1 - 0.14 11.1 0.0 12 4.7 0.0 2.8 3 0 0 3 3 3 0 DegT/DnrJ/EryC1/StrS aminotransferase family RF-1 PF00472.15 EEQ70267.1 - 5.2e-24 84.2 4.0 7.3e-24 83.7 2.8 1.2 1 0 0 1 1 1 1 RF-1 domain DDHD PF02862.12 EEQ70267.1 - 0.44 10.3 2.5 0.68 9.6 1.8 1.3 1 0 0 1 1 1 0 DDHD domain DUF1327 PF07041.6 EEQ70269.1 - 0.086 12.7 0.9 0.097 12.5 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) DUF3317 PF11779.3 EEQ70271.1 - 2.3e-23 81.4 3.2 3e-23 81.0 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) DUF2346 PF09803.4 EEQ70272.1 - 0.0028 17.4 1.3 0.0047 16.7 0.9 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) ECH PF00378.15 EEQ70273.1 - 4.3e-26 91.5 0.0 5.1e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family D123 PF07065.9 EEQ70274.1 - 1.2e-92 310.2 2.7 8.7e-91 304.0 0.0 2.8 1 1 2 3 3 3 2 D123 Voldacs PF03517.8 EEQ70274.1 - 2.4 8.0 10.6 0.31 10.8 1.3 3.0 3 0 0 3 3 3 0 Regulator of volume decrease after cellular swelling Vps51 PF08700.6 EEQ70275.1 - 5.6e-15 54.9 0.0 2.3e-14 52.9 0.0 2.0 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.4 EEQ70275.1 - 0.00086 19.2 3.7 2.1 8.2 0.5 3.8 3 0 0 3 3 3 3 Golgi transport complex subunit 5 DUF1640 PF07798.6 EEQ70276.1 - 5.2e-14 52.6 5.1 1.2e-13 51.4 3.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) ALMT PF11744.3 EEQ70276.1 - 0.046 12.3 1.5 0.069 11.7 1.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Baculo_PEP_C PF04513.7 EEQ70276.1 - 0.047 13.5 3.8 0.085 12.6 2.7 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HEAT_2 PF13646.1 EEQ70277.1 - 2.5e-14 53.3 2.5 0.00041 20.5 0.0 6.0 5 1 2 7 7 7 3 HEAT repeats HEAT PF02985.17 EEQ70277.1 - 1.8e-12 46.2 9.1 0.012 15.6 0.0 8.3 8 0 0 8 8 8 4 HEAT repeat Vac14_Fab1_bd PF12755.2 EEQ70277.1 - 0.015 15.6 0.0 0.64 10.4 0.0 3.4 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Transcrip_reg PF01709.15 EEQ70278.1 - 5.7e-64 215.4 0.1 6.5e-64 215.2 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator CENP-I PF07778.6 EEQ70279.1 - 4.5e-86 289.0 0.0 6.6e-86 288.5 0.0 1.1 1 0 0 1 1 1 1 Mis6 CLPTM1 PF05602.7 EEQ70280.1 - 1.4e-168 561.1 0.0 1.7e-168 560.8 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1240 PF06836.7 EEQ70280.1 - 3.8 7.8 6.6 0.9 9.7 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) adh_short PF00106.20 EEQ70281.1 - 2.5e-13 50.3 0.0 7.8e-13 48.6 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ70281.1 - 2.5e-06 27.4 0.0 3.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ70281.1 - 0.00014 21.6 0.0 0.00038 20.1 0.0 1.7 2 1 0 2 2 2 1 KR domain ASXH PF13919.1 EEQ70282.1 - 3.4e-44 149.9 0.7 4.9e-44 149.4 0.5 1.2 1 0 0 1 1 1 1 Asx homology domain Lactonase PF10282.4 EEQ70282.1 - 0.091 11.8 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Mucin PF01456.12 EEQ70282.1 - 0.22 11.2 5.2 0.46 10.2 3.6 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Longin PF13774.1 EEQ70283.1 - 1.6e-27 94.8 0.1 2.6e-27 94.1 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EEQ70283.1 - 6.6e-13 48.0 0.0 9.4e-13 47.5 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Elong_Iki1 PF10483.4 EEQ70284.1 - 6.1e-89 298.0 0.0 7.2e-89 297.8 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 DUF1777 PF08648.7 EEQ70285.1 - 4.7e-24 85.0 48.8 4.7e-24 85.0 33.8 3.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 EEQ70285.1 - 3.9 5.8 25.2 4.5 5.6 17.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DAO PF01266.19 EEQ70286.1 - 1.4e-61 208.3 0.6 2.2e-61 207.7 0.4 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEQ70286.1 - 1.7e-06 27.9 0.3 4.3e-06 26.6 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEQ70286.1 - 5.9e-06 26.3 0.7 0.091 12.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEQ70286.1 - 0.00011 21.2 0.2 0.0088 14.9 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EEQ70286.1 - 0.00053 20.3 0.7 0.0019 18.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEQ70286.1 - 0.0016 17.3 0.3 1 8.1 0.1 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Trp_halogenase PF04820.9 EEQ70286.1 - 0.0023 16.6 0.7 0.17 10.4 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.1 EEQ70286.1 - 0.0038 17.0 0.7 0.24 11.1 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Strep_67kDa_ant PF06100.6 EEQ70286.1 - 0.0083 14.5 0.1 0.013 13.9 0.1 1.2 1 0 0 1 1 1 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family Pyr_redox_3 PF13738.1 EEQ70286.1 - 0.025 14.6 0.1 8.6 6.3 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEQ70286.1 - 0.028 13.5 0.1 0.052 12.6 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Mqo PF06039.10 EEQ70286.1 - 0.13 10.3 0.0 6.6 4.7 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Fasciclin PF02469.17 EEQ70287.1 - 2e-15 56.9 0.0 1.6e-12 47.5 0.0 2.9 2 1 0 2 2 2 2 Fasciclin domain APH PF01636.18 EEQ70290.1 - 2.2e-12 47.2 0.0 1.4e-11 44.5 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ70290.1 - 0.003 17.1 0.0 0.0051 16.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EEQ70290.1 - 0.0036 16.5 0.0 0.061 12.4 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Glyco_hydro_63 PF03200.11 EEQ70292.1 - 1.5e-250 833.3 0.0 1.4e-249 830.2 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EEQ70292.1 - 0.003 16.2 3.0 0.031 12.9 1.8 2.1 1 1 1 2 2 2 1 Trehalase Bac_rhamnosid PF05592.6 EEQ70292.1 - 0.015 13.5 0.0 0.023 12.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase MMtag PF10159.4 EEQ70293.1 - 1.5e-32 111.4 2.6 2.9e-32 110.5 1.8 1.5 1 0 0 1 1 1 1 Kinase phosphorylation protein CRT10 PF08728.5 EEQ70294.1 - 3.8e-16 58.2 0.0 9.6e-09 33.7 0.0 2.1 2 0 0 2 2 2 2 CRT10 RWD PF05773.17 EEQ70295.1 - 2.3e-18 66.1 0.1 4.6e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 EEQ70295.1 - 1.6e-16 59.8 41.3 1.3e-12 47.3 3.5 4.1 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 EEQ70295.1 - 0.0023 17.7 10.4 0.0023 17.7 7.2 3.8 2 1 1 3 3 3 1 Ring finger domain PAP2 PF01569.16 EEQ70296.1 - 2.3e-14 53.1 1.9 2.3e-14 53.1 1.3 1.9 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.9 EEQ70296.1 - 0.0015 18.2 0.1 0.037 13.7 0.0 2.3 2 0 0 2 2 2 1 Divergent PAP2 family DUF3402 PF11882.3 EEQ70297.1 - 7.3e-162 539.0 0.0 9.2e-162 538.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EEQ70297.1 - 1.5e-98 329.3 0.0 2.4e-98 328.6 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein Prok_Ub PF14454.1 EEQ70297.1 - 0.14 11.8 1.4 0.46 10.1 0.1 2.6 3 0 0 3 3 3 0 Prokaryotic Ubiquitin Ldh_2 PF02615.9 EEQ70298.1 - 1.7e-102 342.5 0.0 2e-102 342.4 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Amidase PF01425.16 EEQ70299.1 - 1.1e-81 274.9 0.0 9.5e-64 215.8 0.1 3.2 2 1 1 3 3 3 3 Amidase Ribosomal_L28e PF01778.12 EEQ70300.1 - 1.4e-32 112.5 0.5 2.5e-32 111.7 0.4 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 EEQ70300.1 - 3.3e-24 84.8 16.8 3.3e-24 84.8 11.6 2.6 2 1 1 3 3 3 1 Mak16 protein C-terminal region BUD22 PF09073.5 EEQ70300.1 - 1.3e-05 24.4 13.2 1.7e-05 24.1 9.1 1.2 1 0 0 1 1 1 1 BUD22 CENP-T PF15511.1 EEQ70300.1 - 0.11 11.6 16.4 0.15 11.2 11.3 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 EEQ70300.1 - 0.16 9.8 31.1 0.2 9.5 21.5 1.1 1 0 0 1 1 1 0 Nop14-like family SGT1 PF07093.6 EEQ70300.1 - 1.8 6.8 14.1 2.3 6.5 9.8 1.2 1 0 0 1 1 1 0 SGT1 protein SAPS PF04499.10 EEQ70300.1 - 2 6.9 5.8 3.3 6.2 4.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIF_alpha PF05793.7 EEQ70300.1 - 4.9 5.4 29.7 7.5 4.7 20.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mso1_Sec1_bdg PF14475.1 EEQ70301.1 - 2.5e-09 36.3 0.0 5.1e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 SOG2 PF10428.4 EEQ70301.1 - 1.1 7.7 7.4 18 3.8 0.0 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein PAT1 PF09770.4 EEQ70301.1 - 8.1 4.5 7.6 9.6 4.2 5.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 E1-E2_ATPase PF00122.15 EEQ70302.1 - 3.1e-17 62.3 0.0 1.1e-16 60.5 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EEQ70302.1 - 1.9e-13 51.3 0.0 5.9e-13 49.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEQ70302.1 - 5.4e-08 33.2 0.0 1.1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ70302.1 - 2.7e-06 27.2 0.0 1.1e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEQ70302.1 - 0.0095 15.5 0.0 0.026 14.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sec16_C PF12931.2 EEQ70303.1 - 3.5e-105 351.8 0.0 4.7e-105 351.3 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16_N PF12935.2 EEQ70303.1 - 1.8e-44 152.5 21.0 1.8e-44 152.5 14.6 4.7 3 1 0 3 3 3 1 Vesicle coat trafficking protein Sec16 N-terminus Sec16 PF12932.2 EEQ70303.1 - 5.7e-33 113.3 0.1 2.5e-32 111.2 0.0 2.1 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region TPR_19 PF14559.1 EEQ70303.1 - 0.036 14.4 0.0 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Hus1 PF04005.7 EEQ70304.1 - 4.6e-106 354.0 0.0 6.4e-106 353.5 0.0 1.2 1 0 0 1 1 1 1 Hus1-like protein GAS2 PF02187.12 EEQ70305.1 - 0.00032 20.3 0.1 0.00066 19.3 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain RabGAP-TBC PF00566.13 EEQ70306.1 - 2.3e-36 125.3 1.6 2.3e-36 125.3 1.1 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 EEQ70306.1 - 2.6e-11 43.2 0.0 2.7e-08 33.3 0.0 3.5 2 1 0 2 2 2 2 Domain of unknown function (DUF3548) DDHD PF02862.12 EEQ70306.1 - 0.078 12.7 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 DDHD domain DUF2360 PF10152.4 EEQ70306.1 - 0.094 12.9 0.2 0.26 11.5 0.2 1.7 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Ring_hydroxyl_A PF00848.14 EEQ70307.1 - 2.1e-29 102.6 2.3 2.1e-28 99.4 1.6 2.1 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 EEQ70308.1 - 4.5e-18 64.5 0.1 9.4e-18 63.5 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.14 EEQ70308.1 - 1.1e-05 25.2 0.5 0.043 13.4 0.0 2.4 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Mpv17_PMP22 PF04117.7 EEQ70310.1 - 1.4e-20 72.6 0.1 4.7e-20 70.9 0.0 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family Polysacc_synt_C PF14667.1 EEQ70310.1 - 0.11 12.2 0.9 0.87 9.3 0.3 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Catalase PF00199.14 EEQ70314.1 - 3.5e-156 519.7 0.2 4.8e-156 519.2 0.2 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EEQ70314.1 - 1.6e-16 59.9 0.0 3.3e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EEQ70314.1 - 2.3e-05 23.8 0.0 4.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DUF1183 PF06682.7 EEQ70316.1 - 0.11 12.0 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Band_3_cyto PF07565.8 EEQ70316.1 - 0.12 11.9 0.9 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain YIF1 PF03878.10 EEQ70318.1 - 1.4e-73 247.0 5.4 4.1e-73 245.4 3.7 1.6 1 1 0 1 1 1 1 YIF1 SRP-alpha_N PF04086.8 EEQ70319.1 - 5.8e-85 285.0 0.0 7.8e-85 284.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 EEQ70319.1 - 2e-49 167.7 0.0 4.1e-49 166.6 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 EEQ70319.1 - 1.6e-07 31.2 1.5 4.1e-07 29.9 0.1 2.4 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 EEQ70319.1 - 1e-06 27.7 0.0 1.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 EEQ70319.1 - 3.7e-06 26.4 0.0 1e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 EEQ70319.1 - 0.00058 19.8 0.0 0.0015 18.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.1 EEQ70319.1 - 0.0016 18.0 0.0 0.0034 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EEQ70319.1 - 0.0028 17.3 0.0 0.0068 16.1 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EEQ70319.1 - 0.026 13.9 0.0 0.093 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA-like domain Fer4_NifH PF00142.13 EEQ70319.1 - 0.04 13.1 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_14 PF13173.1 EEQ70319.1 - 0.043 13.7 0.1 0.41 10.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 EEQ70319.1 - 0.045 13.7 0.0 0.17 11.8 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase MFS_1 PF07690.11 EEQ70322.1 - 1.5e-40 139.0 45.6 1.2e-35 122.8 13.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ70322.1 - 2.7e-11 42.7 7.3 2.7e-11 42.7 5.1 2.6 1 1 1 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 EEQ70322.1 - 4.4e-07 28.6 15.3 1.9e-05 23.2 2.3 4.0 1 1 1 2 2 2 2 MFS/sugar transport protein Folate_carrier PF01770.13 EEQ70322.1 - 0.00015 20.4 0.2 0.00015 20.4 0.2 1.6 2 0 0 2 2 2 1 Reduced folate carrier MFS_1_like PF12832.2 EEQ70322.1 - 0.0089 15.7 2.6 0.054 13.2 0.1 3.3 2 1 1 3 3 3 1 MFS_1 like family MFS_1 PF07690.11 EEQ70323.1 - 9.1e-16 57.5 43.3 1.9e-14 53.1 28.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RGS PF00615.14 EEQ70324.1 - 0.068 13.2 0.1 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 Regulator of G protein signaling domain Ribosomal_L14e PF01929.12 EEQ70325.1 - 1.9e-26 92.2 0.5 2.8e-26 91.6 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EEQ70325.1 - 1.9e-08 33.7 1.5 3.3e-08 32.9 1.0 1.4 1 0 0 1 1 1 1 KOW motif AAA_19 PF13245.1 EEQ70325.1 - 0.19 11.4 2.6 0.98 9.2 0.0 2.6 2 1 1 3 3 3 0 Part of AAA domain NAC PF01849.13 EEQ70326.1 - 6.2e-24 83.2 0.1 8.7e-23 79.6 0.0 2.4 3 0 0 3 3 3 1 NAC domain UBA PF00627.26 EEQ70326.1 - 0.00077 19.2 0.3 0.0017 18.1 0.2 1.6 1 0 0 1 1 1 1 UBA/TS-N domain CDC45 PF02724.9 EEQ70326.1 - 0.066 11.2 2.2 0.094 10.7 1.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SpoIIIAH PF12685.2 EEQ70326.1 - 0.36 10.2 8.4 0.09 12.2 3.2 1.7 2 0 0 2 2 2 0 SpoIIIAH-like protein Mt_ATP-synt_D PF05873.7 EEQ70327.1 - 7.8e-17 61.3 1.6 1e-16 61.0 1.1 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) EzrA PF06160.7 EEQ70327.1 - 0.0061 14.8 4.1 0.0084 14.3 2.9 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA TPR_MLP1_2 PF07926.7 EEQ70327.1 - 0.04 13.6 2.0 0.065 12.9 1.4 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Blt1 PF12754.2 EEQ70327.1 - 0.068 12.7 0.7 0.09 12.3 0.5 1.2 1 0 0 1 1 1 0 Cell-cycle control medial ring component Tropomyosin_1 PF12718.2 EEQ70327.1 - 0.069 12.9 9.9 0.82 9.5 0.2 2.4 1 1 0 2 2 2 0 Tropomyosin like Laminin_II PF06009.7 EEQ70327.1 - 0.081 12.6 4.3 3.1 7.5 0.1 2.3 2 0 0 2 2 2 0 Laminin Domain II DUF4515 PF14988.1 EEQ70327.1 - 0.26 10.9 5.3 1.7 8.2 0.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) GATase_2 PF00310.16 EEQ70329.1 - 9.6e-20 70.5 0.1 2.7e-16 59.2 0.0 2.5 2 1 1 3 3 3 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EEQ70329.1 - 5.5e-13 49.0 0.0 1.2e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EEQ70329.1 - 2.7e-12 46.5 0.0 5.2e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EEQ70329.1 - 2.8e-12 46.4 0.1 5.2e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EEQ70329.1 - 1.6e-06 27.0 0.0 3.8e-06 25.7 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferases class-II PRTase_2 PF15609.1 EEQ70329.1 - 0.065 12.5 0.0 0.15 11.3 0.0 1.4 1 1 0 1 1 1 0 Phosphoribosyl transferase DNA_photolyase PF00875.13 EEQ70329.1 - 0.12 12.1 0.0 0.52 10.0 0.0 1.9 2 0 0 2 2 2 0 DNA photolyase DNA_methylase PF00145.12 EEQ70330.1 - 1.2e-37 129.8 0.0 5.2e-28 98.1 0.0 2.1 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase SET PF00856.23 EEQ70331.1 - 1.5e-19 70.8 0.6 3.7e-13 50.1 0.0 2.4 2 0 0 2 2 2 2 SET domain MmgE_PrpD PF03972.9 EEQ70332.1 - 3.4e-151 503.4 0.0 3.9e-151 503.2 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Abhydrolase_6 PF12697.2 EEQ70333.1 - 1.7e-11 44.4 0.0 2.1e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ70333.1 - 0.0019 17.9 0.0 0.0027 17.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PBP PF01161.15 EEQ70334.1 - 0.0029 17.4 1.4 0.0074 16.1 0.0 2.2 2 1 0 2 2 2 1 Phosphatidylethanolamine-binding protein AMP-binding PF00501.23 EEQ70335.1 - 1.3e-75 254.4 0.0 1.7e-75 254.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ70335.1 - 2.1e-11 44.5 0.2 5.1e-11 43.3 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1661 PF07877.6 EEQ70335.1 - 0.27 10.7 2.2 0.33 10.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1661) DNA_pol_A_exo1 PF01612.15 EEQ70336.1 - 3e-10 39.8 0.0 9e-10 38.3 0.0 1.6 2 0 0 2 2 2 1 3'-5' exonuclease Citrate_synt PF00285.16 EEQ70339.1 - 9.8e-101 337.0 0.0 1.3e-100 336.6 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase ICL PF00463.16 EEQ70340.1 - 4.3e-180 599.4 0.0 4.8e-180 599.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EEQ70340.1 - 8.3e-11 41.5 0.0 9.3e-10 38.1 0.0 2.1 1 1 1 2 2 2 1 Phosphoenolpyruvate phosphomutase Toxin_61 PF15538.1 EEQ70340.1 - 0.1 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 61 ABC_tran PF00005.22 EEQ70341.1 - 1.5e-47 161.3 0.0 4.4e-26 91.7 0.0 3.9 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EEQ70341.1 - 1.2e-16 61.5 0.2 0.0016 18.4 0.0 4.2 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 EEQ70341.1 - 1.7e-12 47.0 0.0 0.00076 18.7 0.0 4.0 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EEQ70341.1 - 1.2e-07 32.2 0.4 0.0013 19.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EEQ70341.1 - 3.7e-07 29.5 0.9 0.014 14.9 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Chromo PF00385.19 EEQ70341.1 - 1.7e-06 27.5 0.0 3.5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SbcCD_C PF13558.1 EEQ70341.1 - 1.6e-05 24.6 0.5 0.62 10.0 0.0 4.1 3 1 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EEQ70341.1 - 2.7e-05 24.9 0.0 0.46 11.3 0.0 3.1 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EEQ70341.1 - 4.3e-05 22.7 0.1 0.12 11.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 EEQ70341.1 - 4.8e-05 22.5 0.0 0.19 10.7 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_10 PF12846.2 EEQ70341.1 - 5.6e-05 22.7 2.8 1 8.7 0.1 4.0 4 0 0 4 4 4 2 AAA-like domain Miro PF08477.8 EEQ70341.1 - 7.8e-05 23.1 0.2 0.19 12.2 0.0 3.1 3 0 0 3 3 2 1 Miro-like protein AAA_22 PF13401.1 EEQ70341.1 - 9.2e-05 22.5 0.0 0.13 12.3 0.0 3.1 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EEQ70341.1 - 0.00012 21.9 0.0 0.48 10.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.12 EEQ70341.1 - 0.00013 21.8 2.2 0.062 13.1 0.1 3.5 4 0 0 4 4 3 1 Domain of unknown function DUF87 NACHT PF05729.7 EEQ70341.1 - 0.0038 16.9 0.2 0.42 10.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 EEQ70341.1 - 0.005 16.9 0.2 4.8 7.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 EEQ70341.1 - 0.0063 16.4 0.0 4.6 7.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain Adaptin_N PF01602.15 EEQ70341.1 - 0.0086 14.4 1.7 0.031 12.6 0.2 2.0 1 1 1 2 2 2 1 Adaptin N terminal region AAA_28 PF13521.1 EEQ70341.1 - 0.009 15.9 0.1 0.62 10.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_13 PF13166.1 EEQ70341.1 - 0.0099 14.3 0.1 1.7 7.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EEQ70341.1 - 0.012 15.2 0.0 7.3 6.3 0.0 2.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EEQ70341.1 - 0.013 14.9 0.2 2.4 7.5 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 EEQ70341.1 - 0.013 15.2 0.0 0.76 9.5 0.0 3.1 4 0 0 4 4 3 0 Dynamin family AAA_25 PF13481.1 EEQ70341.1 - 0.024 14.0 0.0 10 5.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EEQ70341.1 - 0.04 14.2 0.8 8 6.7 0.0 3.0 2 1 0 2 2 2 0 AAA domain ArgK PF03308.11 EEQ70341.1 - 0.042 12.6 0.9 5.8 5.6 0.0 2.4 2 0 0 2 2 2 0 ArgK protein ParcG PF10274.4 EEQ70341.1 - 0.049 13.5 0.2 6.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Parkin co-regulated protein ATP-synt_ab PF00006.20 EEQ70341.1 - 0.078 12.4 0.1 16 4.9 0.0 2.8 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain HEAT PF02985.17 EEQ70341.1 - 0.15 12.2 3.9 77 3.7 0.0 5.1 6 0 0 6 6 4 0 HEAT repeat HEAT_2 PF13646.1 EEQ70341.1 - 0.15 12.3 7.2 22 5.4 5.0 3.5 1 1 0 1 1 1 0 HEAT repeats DUF3584 PF12128.3 EEQ70341.1 - 0.25 8.6 2.4 2.7 5.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) HEAT_EZ PF13513.1 EEQ70341.1 - 3.5 8.2 9.8 47 4.6 0.0 4.8 4 2 1 5 5 4 0 HEAT-like repeat Peptidase_C53 PF05550.6 EEQ70342.1 - 0.021 14.3 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Pestivirus Npro endopeptidase C53 AA_permease_2 PF13520.1 EEQ70343.1 - 2e-48 165.0 47.8 2.3e-48 164.7 33.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ70343.1 - 4.1e-25 88.0 36.4 5.6e-25 87.6 25.2 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1049 PF06305.6 EEQ70343.1 - 0.089 12.2 0.1 0.8 9.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Glyco_hydro_3 PF00933.16 EEQ70344.1 - 5.7e-85 284.9 0.0 8e-85 284.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EEQ70344.1 - 6.6e-52 176.2 0.1 1.7e-50 171.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EEQ70344.1 - 2.6e-20 72.1 1.2 4.1e-17 61.8 0.1 2.5 2 0 0 2 2 2 2 Fibronectin type III-like domain Malate_synthase PF01274.17 EEQ70345.1 - 7.5e-234 776.5 0.0 8.5e-234 776.3 0.0 1.0 1 0 0 1 1 1 1 Malate synthase ADH_N PF08240.7 EEQ70346.1 - 9e-29 99.4 2.9 2e-28 98.3 2.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ70346.1 - 3.7e-22 78.2 0.4 7.5e-22 77.2 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEQ70346.1 - 1.9e-05 25.5 0.0 4.3e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EEQ70346.1 - 0.033 13.7 0.2 0.074 12.6 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 EEQ70346.1 - 0.085 12.9 0.3 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EEQ70346.1 - 0.14 11.7 0.8 0.25 10.9 0.6 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MPC PF03650.8 EEQ70347.1 - 2.1e-41 140.6 0.2 3.1e-41 140.0 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) L51_S25_CI-B8 PF05047.11 EEQ70348.1 - 5.9e-12 45.1 0.0 7.9e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LigB PF02900.13 EEQ70349.1 - 3.4e-48 164.0 0.1 3.7e-48 163.8 0.1 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Sel1 PF08238.7 EEQ70351.1 - 5.5e-46 153.9 29.6 2e-09 37.7 0.4 7.9 7 0 0 7 7 7 7 Sel1 repeat CBP4 PF07960.6 EEQ70354.1 - 4.5e-36 123.2 1.8 5.4e-36 123.0 1.2 1.0 1 0 0 1 1 1 1 CBP4 DUF922 PF06037.6 EEQ70354.1 - 0.012 15.0 3.6 0.015 14.6 2.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) Trp_oprn_chp PF09534.5 EEQ70354.1 - 0.016 14.7 0.0 0.031 13.9 0.0 1.4 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Metal_hydrol PF10118.4 EEQ70354.1 - 0.037 13.4 4.6 0.042 13.2 3.2 1.1 1 0 0 1 1 1 0 Predicted metal-dependent hydrolase DUF342 PF03961.8 EEQ70354.1 - 0.044 12.2 1.1 0.045 12.1 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) hDGE_amylase PF14701.1 EEQ70354.1 - 0.17 10.7 2.2 0.21 10.4 1.5 1.0 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme DUF4207 PF13904.1 EEQ70354.1 - 0.23 10.8 11.5 0.28 10.5 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) AAA_11 PF13086.1 EEQ70354.1 - 0.26 10.8 3.9 0.29 10.6 2.7 1.0 1 0 0 1 1 1 0 AAA domain MRP-S26 PF14943.1 EEQ70354.1 - 8.1 5.9 15.0 15 5.1 10.1 1.5 1 1 1 2 2 2 0 Mitochondrial ribosome subunit S26 Glyco_hydro_76 PF03663.9 EEQ70355.1 - 2.2e-147 491.3 12.3 2.9e-147 490.9 8.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EEQ70355.1 - 0.0098 14.9 8.5 0.13 11.3 1.5 2.9 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 SAP PF02037.22 EEQ70356.1 - 1.2e-09 37.4 0.1 2.6e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 SAP domain COX16 PF14138.1 EEQ70357.1 - 0.026 14.7 0.1 0.026 14.7 0.1 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 DUF1751 PF08551.5 EEQ70359.1 - 0.054 13.8 0.4 0.071 13.4 0.3 1.3 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) DUF4491 PF14898.1 EEQ70359.1 - 0.094 12.8 3.8 0.12 12.5 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) Asp PF00026.18 EEQ70360.1 - 1.1e-47 162.7 0.0 1.6e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EEQ70360.1 - 1.4e-07 31.8 0.0 0.019 15.4 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EEQ70360.1 - 7.2e-05 22.8 0.0 0.00017 21.5 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal RVP PF00077.15 EEQ70360.1 - 0.058 13.3 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EEQ70360.1 - 0.17 11.7 0.0 17 5.3 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease 4HBT PF03061.17 EEQ70361.1 - 0.00064 19.7 0.1 0.33 11.1 0.1 2.4 2 0 0 2 2 2 2 Thioesterase superfamily DUF3945 PF13101.1 EEQ70361.1 - 0.027 13.7 0.0 5.9 6.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3945) Vfa1 PF08432.5 EEQ70362.1 - 4.5e-62 209.3 14.6 5e-62 209.1 10.1 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF2347 PF09804.4 EEQ70362.1 - 0.087 12.0 0.7 0.12 11.6 0.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) RR_TM4-6 PF06459.7 EEQ70362.1 - 0.16 11.8 10.0 0.23 11.3 6.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 EEQ70362.1 - 0.38 10.1 19.5 0.5 9.6 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NPR3 PF03666.8 EEQ70362.1 - 0.6 8.5 7.5 0.77 8.2 5.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RNA_polI_A34 PF08208.6 EEQ70362.1 - 0.76 9.4 21.7 1.2 8.8 15.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Ycf1 PF05758.7 EEQ70362.1 - 0.92 7.1 9.8 0.99 7.0 6.8 1.0 1 0 0 1 1 1 0 Ycf1 DUF4407 PF14362.1 EEQ70362.1 - 3 6.7 4.4 3.8 6.3 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC45 PF02724.9 EEQ70362.1 - 7.2 4.5 17.1 8.9 4.2 11.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.11 EEQ70362.1 - 7.6 6.3 7.1 10 5.9 4.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Sec62 PF03839.11 EEQ70362.1 - 8 5.7 13.7 11 5.2 9.5 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 eIF-3c_N PF05470.7 EEQ70362.1 - 8.2 4.3 15.1 9.5 4.1 10.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus NUDIX PF00293.23 EEQ70363.1 - 1.1e-13 51.0 0.0 1.5e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DSPc PF00782.15 EEQ70364.1 - 3e-23 81.8 0.0 3.9e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EEQ70364.1 - 0.0021 17.0 0.0 0.0029 16.5 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 EEQ70364.1 - 0.018 14.3 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EEQ70364.1 - 0.049 13.8 0.0 0.078 13.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family EBV-NA3 PF05009.7 EEQ70364.1 - 0.053 12.7 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) IBR PF01485.16 EEQ70364.1 - 0.26 11.1 5.1 2.3 8.1 0.3 2.4 2 0 0 2 2 2 0 IBR domain HMG_box PF00505.14 EEQ70368.1 - 2.3e-06 27.7 0.2 2.3e-06 27.7 0.1 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EEQ70368.1 - 3.2e-05 24.2 0.3 3.2e-05 24.2 0.2 1.9 2 0 0 2 2 2 1 HMG-box domain DDHD PF02862.12 EEQ70368.1 - 0.22 11.2 5.0 0.36 10.5 3.4 1.3 1 0 0 1 1 1 0 DDHD domain Nucleoplasmin PF03066.10 EEQ70368.1 - 0.55 9.7 8.1 1.2 8.6 5.6 1.5 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 EEQ70368.1 - 1.4 6.9 6.3 2 6.3 4.4 1.2 1 0 0 1 1 1 0 CDC45-like protein SpoIIIAH PF12685.2 EEQ70368.1 - 1.5 8.3 8.6 2.6 7.5 6.0 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein EBV-NA3 PF05009.7 EEQ70368.1 - 1.6 7.9 4.0 2.2 7.4 2.8 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Lin-8 PF03353.10 EEQ70368.1 - 2.8 7.1 8.1 4.4 6.4 5.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4551 PF15087.1 EEQ70368.1 - 3.2 6.0 5.2 4.1 5.6 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CENP-B_dimeris PF09026.5 EEQ70368.1 - 3.8 7.8 9.7 7.9 6.7 6.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pkinase PF00069.20 EEQ70369.1 - 2e-29 102.5 0.0 3e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ70369.1 - 3.3e-06 26.3 0.0 0.012 14.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Amidohydro_1 PF01979.15 EEQ70370.1 - 4.5e-62 210.6 1.9 7.3e-62 209.9 1.3 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 EEQ70370.1 - 6e-53 178.1 1.2 6e-53 178.1 0.8 2.6 3 0 0 3 3 3 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EEQ70370.1 - 1.2e-30 105.2 0.1 3.3e-29 100.6 0.0 2.6 2 1 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 EEQ70370.1 - 3.3e-27 94.4 0.1 1.2e-26 92.5 0.1 2.0 1 1 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 EEQ70370.1 - 1.3e-05 24.9 5.9 3.8e-05 23.4 4.1 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EEQ70370.1 - 1.5e-05 24.4 0.2 0.0013 18.0 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.9 EEQ70370.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase DRMBL PF07522.9 EEQ70371.1 - 7.7e-09 35.5 0.0 3.7e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase RMMBL PF07521.7 EEQ70371.1 - 0.015 15.0 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA-metabolising metallo-beta-lactamase DUF3435 PF11917.3 EEQ70372.1 - 8.7e-27 93.8 0.1 3.3e-13 49.1 0.0 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF3435) ADP_PFK_GK PF04587.10 EEQ70377.1 - 0.034 12.3 0.0 0.071 11.3 0.0 1.5 2 0 0 2 2 2 0 ADP-specific Phosphofructokinase/Glucokinase conserved region NPR2 PF06218.6 EEQ70378.1 - 1.9e-133 445.3 0.0 5.2e-133 443.8 0.0 1.6 2 0 0 2 2 2 1 Nitrogen permease regulator 2 LAT PF15234.1 EEQ70378.1 - 0.081 12.3 0.5 0.18 11.2 0.4 1.5 1 0 0 1 1 1 0 Linker for activation of T-cells Afi1 PF07792.7 EEQ70378.1 - 0.1 12.6 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Ada3 PF10198.4 EEQ70379.1 - 1.3e-43 147.9 0.0 3.1e-43 146.6 0.0 1.7 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 zf-RING_2 PF13639.1 EEQ70380.1 - 1.8e-13 50.0 5.8 3.3e-13 49.2 4.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEQ70380.1 - 1.5e-06 28.0 4.9 3.2e-06 27.0 3.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ70380.1 - 1.5e-06 27.7 3.3 2.8e-06 26.9 2.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EEQ70380.1 - 3.6e-06 26.5 1.9 6.3e-06 25.7 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ70380.1 - 8.9e-06 25.2 4.1 1.6e-05 24.4 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEQ70380.1 - 9.1e-05 22.5 4.4 0.00022 21.2 3.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EEQ70380.1 - 0.0015 18.3 1.9 0.0037 17.0 1.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EEQ70380.1 - 0.0026 17.4 1.3 0.0092 15.6 0.1 2.3 1 1 1 2 2 2 1 RING-type zinc-finger PMP1_2 PF08114.6 EEQ70380.1 - 0.019 14.4 1.7 0.036 13.5 1.2 1.4 1 0 0 1 1 1 0 ATPase proteolipid family zf-RING_4 PF14570.1 EEQ70380.1 - 0.059 12.9 4.0 0.11 12.0 2.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 EEQ70380.1 - 0.085 12.3 3.1 0.19 11.2 2.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.6 EEQ70380.1 - 0.25 11.3 1.5 0.52 10.3 1.1 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 EEQ70380.1 - 0.27 11.1 5.7 1.2 9.0 3.9 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-MIZ PF02891.15 EEQ70380.1 - 0.45 10.0 4.5 1.1 8.8 3.1 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger FRG1 PF06229.7 EEQ70381.1 - 1.1e-60 204.3 0.0 1.5e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 EEQ70381.1 - 0.013 15.5 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 Fascin domain ADH_N PF08240.7 EEQ70382.1 - 2.7e-35 120.4 2.3 7.2e-35 119.0 1.5 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ70382.1 - 1.1e-15 57.2 0.0 1.8e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEQ70382.1 - 0.00013 22.8 0.0 0.00023 22.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EEQ70382.1 - 0.0027 18.2 0.0 0.0057 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_7 PF13241.1 EEQ70382.1 - 0.0058 16.8 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Saccharop_dh PF03435.13 EEQ70382.1 - 0.028 13.4 0.0 0.033 13.1 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Gp_dh_N PF00044.19 EEQ70382.1 - 0.028 14.3 0.0 0.072 13.0 0.0 1.6 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EEQ70382.1 - 0.044 12.8 0.2 0.07 12.1 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain NADH_4Fe-4S PF10589.4 EEQ70382.1 - 0.1 11.7 0.8 0.37 9.9 0.6 1.9 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region DUF2338 PF10100.4 EEQ70382.1 - 0.11 10.8 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) HECT PF00632.20 EEQ70383.1 - 1.3e-75 254.4 0.0 1.8e-75 254.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4360 PF14273.1 EEQ70384.1 - 8.3e-45 152.6 0.8 1.8e-43 148.3 0.5 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4360) Ribosomal_L15e PF00827.12 EEQ70385.1 - 8.2e-91 302.7 11.5 9.4e-91 302.5 8.0 1.0 1 0 0 1 1 1 1 Ribosomal L15 PSP1 PF04468.7 EEQ70387.1 - 7.9e-31 105.8 1.3 1.3e-30 105.2 0.9 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Nfu_N PF08712.6 EEQ70390.1 - 1.9e-26 91.5 0.0 4.7e-26 90.2 0.0 1.7 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EEQ70390.1 - 9.1e-23 79.8 0.0 1.5e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain RasGEF PF00617.14 EEQ70391.1 - 1.3e-44 152.2 0.1 2.2e-44 151.4 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EEQ70391.1 - 1.1e-14 54.3 0.0 2.8e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 EEQ70391.1 - 4.7e-11 43.2 0.0 1e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein FtsK_SpoIIIE PF01580.13 EEQ70391.1 - 0.14 11.5 0.0 0.33 10.3 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family zf-HIT PF04438.11 EEQ70392.1 - 4.5e-10 38.9 8.8 7.3e-10 38.3 6.1 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-B_box PF00643.19 EEQ70392.1 - 1.3 8.9 8.9 2 8.3 6.1 1.3 1 0 0 1 1 1 0 B-box zinc finger Complex1_LYR_2 PF13233.1 EEQ70393.1 - 4.1e-19 68.9 0.6 5.2e-19 68.6 0.4 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Cyclin_N PF00134.18 EEQ70394.1 - 1.4e-12 47.2 0.0 4.5e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.6 EEQ70394.1 - 7.4e-09 36.1 0.0 1.2e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin MreB_Mbl PF06723.8 EEQ70396.1 - 0.04 12.5 0.1 0.78 8.2 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein HSP70 PF00012.15 EEQ70396.1 - 0.063 11.1 0.0 0.1 10.5 0.0 1.3 1 0 0 1 1 1 0 Hsp70 protein DDR PF08841.5 EEQ70396.1 - 0.12 11.1 0.0 1.6 7.4 0.0 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain ODC_AZ PF02100.12 EEQ70398.1 - 1e-27 95.7 0.0 1.6e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Yippee-Mis18 PF03226.9 EEQ70399.1 - 1e-24 86.3 0.1 1.6e-24 85.7 0.1 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Transp_Tc5_C PF04236.10 EEQ70399.1 - 0.051 13.7 0.1 0.42 10.8 0.0 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain RIG-I_C-RD PF11648.3 EEQ70399.1 - 0.065 13.0 0.5 1.8 8.4 0.0 2.1 2 0 0 2 2 2 0 C-terminal domain of RIG-I SHNi-TPR PF10516.4 EEQ70400.1 - 3.8e-14 51.6 0.3 3.8e-14 51.6 0.2 3.0 3 0 0 3 3 3 1 SHNi-TPR TPR_11 PF13414.1 EEQ70400.1 - 6.6e-07 28.8 6.5 0.0077 15.8 0.6 3.1 2 1 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 EEQ70400.1 - 1.2e-06 28.3 8.9 0.0038 17.1 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ70400.1 - 0.0023 18.5 3.5 0.55 10.9 0.6 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat Med9 PF07544.8 EEQ70400.1 - 0.0097 15.6 3.4 0.0097 15.6 2.4 2.5 3 0 0 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 TPR_1 PF00515.23 EEQ70400.1 - 0.032 13.8 3.1 1.2 8.9 0.4 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.2 EEQ70400.1 - 0.095 12.5 1.9 4.3 7.1 0.1 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) TBPIP PF07106.8 EEQ70400.1 - 0.13 11.7 9.8 0.026 14.0 2.7 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_2 PF07719.12 EEQ70400.1 - 0.23 11.4 15.7 1.2 9.1 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ70400.1 - 0.33 10.8 3.9 66 3.6 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ70400.1 - 0.74 9.7 3.4 37 4.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ70400.1 - 0.81 10.5 4.1 25 5.8 0.1 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_3 PF07720.7 EEQ70400.1 - 1.9 8.3 6.1 2.7 7.8 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat LUC7 PF03194.10 EEQ70400.1 - 3.9 6.9 17.2 0.063 12.8 6.1 2.2 3 1 0 3 3 3 0 LUC7 N_terminus DNA_pol_E_B PF04042.11 EEQ70401.1 - 4e-48 163.4 0.3 5.5e-48 162.9 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Med14 PF08638.6 EEQ70402.1 - 6.9e-74 247.3 0.1 1.3e-73 246.3 0.1 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 Thioredoxin PF00085.15 EEQ70403.1 - 1.9e-61 204.2 3.3 1.4e-31 108.2 0.0 3.9 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 EEQ70403.1 - 3e-51 173.8 1.8 3.2e-38 131.3 0.4 3.7 2 1 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EEQ70403.1 - 2.1e-09 37.5 0.9 0.0036 17.4 0.1 3.7 3 2 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EEQ70403.1 - 9.7e-09 35.2 0.1 0.0091 16.0 0.0 3.7 4 1 1 5 5 5 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EEQ70403.1 - 2.1e-08 34.0 0.4 0.0033 17.4 0.0 3.1 3 1 0 3 3 3 2 Thioredoxin-like Calsequestrin PF01216.12 EEQ70403.1 - 6.3e-07 28.5 3.3 1.3e-06 27.4 2.3 1.5 1 1 0 1 1 1 1 Calsequestrin AhpC-TSA PF00578.16 EEQ70403.1 - 1.6e-05 24.5 2.7 0.021 14.4 0.1 3.0 3 1 1 4 4 4 2 AhpC/TSA family Redoxin PF08534.5 EEQ70403.1 - 0.002 17.6 4.0 0.58 9.6 0.0 3.4 4 0 0 4 4 4 2 Redoxin ERp29_N PF07912.8 EEQ70403.1 - 0.006 16.5 0.2 4.1 7.3 0.0 3.8 3 1 1 4 4 4 1 ERp29, N-terminal domain UDG PF03167.14 EEQ70404.1 - 8.6e-24 83.7 0.1 1.2e-23 83.2 0.1 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Actin PF00022.14 EEQ70405.1 - 9.8e-139 462.1 0.0 1.1e-138 461.9 0.0 1.0 1 0 0 1 1 1 1 Actin Hep_59 PF07052.6 EEQ70406.1 - 1.1e-25 89.9 1.0 1.1e-25 89.9 0.7 3.0 3 1 1 4 4 4 1 Hepatocellular carcinoma-associated antigen 59 Pol_alpha_B_N PF08418.5 EEQ70406.1 - 0.048 13.1 3.1 0.33 10.4 0.6 2.2 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal DUF4629 PF15442.1 EEQ70406.1 - 1.9 8.5 8.3 1.2 9.2 0.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4629) TRP PF06011.7 EEQ70407.1 - 5.9e-141 469.9 11.4 7.4e-141 469.6 7.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EEQ70407.1 - 3.5e-37 127.5 0.2 5.1e-37 127.0 0.2 1.3 1 0 0 1 1 1 1 ML-like domain SCIMP PF15050.1 EEQ70407.1 - 0.9 9.4 6.2 1.1 9.1 0.1 2.9 2 0 0 2 2 2 0 SCIMP protein RRM_1 PF00076.17 EEQ70408.1 - 2.6e-36 123.0 0.3 6.6e-18 64.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ70408.1 - 8.5e-28 96.1 0.1 7.8e-13 48.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ70408.1 - 2.6e-13 49.5 0.0 2.1e-06 27.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EEQ70408.1 - 0.0089 15.8 0.1 2.4 8.0 0.0 2.5 2 0 0 2 2 2 2 RNA binding motif CENP-U PF13097.1 EEQ70409.1 - 0.3 11.0 2.8 0.35 10.7 1.9 1.1 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit DUF605 PF04652.11 EEQ70409.1 - 0.51 9.6 10.8 0.57 9.5 7.5 1.0 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EEQ70409.1 - 0.61 8.2 8.2 0.66 8.1 5.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IER PF05760.7 EEQ70409.1 - 0.72 9.7 5.2 0.83 9.5 3.6 1.0 1 0 0 1 1 1 0 Immediate early response protein (IER) RabGAP-TBC PF00566.13 EEQ70410.1 - 1.1e-48 165.6 0.0 1.9e-48 164.7 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RrnaAD PF00398.15 EEQ70411.1 - 7.1e-48 162.9 0.0 9.7e-48 162.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EEQ70411.1 - 1.4e-09 38.0 0.0 2.1e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ70411.1 - 1.1e-07 32.4 0.0 1.8e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ70411.1 - 4.4e-05 23.8 0.0 8.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ70411.1 - 0.00018 21.9 0.0 0.00032 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ70411.1 - 0.00027 20.5 0.0 0.00047 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ70411.1 - 0.0003 20.2 0.0 0.00048 19.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EEQ70411.1 - 0.0015 18.3 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EEQ70411.1 - 0.019 14.4 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EEQ70411.1 - 0.028 13.4 0.0 0.056 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Snf7 PF03357.16 EEQ70411.1 - 0.04 13.2 1.4 0.09 12.1 1.0 1.5 1 0 0 1 1 1 0 Snf7 Methyltransf_2 PF00891.13 EEQ70411.1 - 0.066 12.3 0.0 0.14 11.2 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase Methyltransf_25 PF13649.1 EEQ70411.1 - 0.093 13.1 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PRP1_N PF06424.7 EEQ70412.1 - 6.5e-54 181.8 5.6 6.5e-54 181.8 3.9 2.0 2 0 0 2 2 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EEQ70412.1 - 1.4e-27 93.6 30.4 0.00014 22.1 0.2 14.1 5 4 10 15 15 15 8 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ70412.1 - 7.5e-25 87.0 12.2 2e-05 24.8 0.2 9.1 6 2 3 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ70412.1 - 4.2e-21 75.0 20.3 0.00015 22.3 0.9 8.6 7 1 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ70412.1 - 1.7e-14 52.4 4.1 0.015 15.1 0.0 9.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ70412.1 - 1.5e-13 50.1 11.5 2.7e-05 23.7 0.0 8.0 6 2 3 9 9 9 4 TPR repeat TPR_8 PF13181.1 EEQ70412.1 - 2.1e-06 27.1 0.2 0.33 10.8 0.1 6.4 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ70412.1 - 2.2e-06 27.0 2.8 0.023 14.3 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ70412.1 - 3.3e-06 26.9 0.4 0.37 10.7 0.2 5.6 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ70412.1 - 0.0003 20.7 7.7 10 6.6 0.1 8.5 10 1 1 11 11 9 0 Tetratricopeptide repeat NARP1 PF12569.3 EEQ70412.1 - 0.00034 19.5 7.7 0.72 8.5 0.0 5.5 4 1 2 6 6 6 2 NMDA receptor-regulated protein 1 Apc3 PF12895.2 EEQ70412.1 - 0.00085 19.4 0.2 1.4 9.1 0.0 3.9 3 1 1 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EEQ70412.1 - 0.0011 18.6 3.4 5.1 7.1 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat Suf PF05843.9 EEQ70412.1 - 0.016 14.9 2.8 4.8 6.8 0.0 4.4 4 1 0 4 4 4 0 Suppressor of forked protein (Suf) TPR_6 PF13174.1 EEQ70412.1 - 0.036 14.5 12.7 21 5.8 0.1 8.0 9 0 0 9 9 8 0 Tetratricopeptide repeat Cutinase PF01083.17 EEQ70412.1 - 0.19 11.4 0.0 14 5.3 0.0 2.6 1 1 1 2 2 2 0 Cutinase SAGA-Tad1 PF12767.2 EEQ70413.1 - 9.3e-58 195.8 0.0 1.2e-57 195.4 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Adhesin_Dr PF04619.7 EEQ70413.1 - 0.06 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Dr-family adhesin BESS PF02944.15 EEQ70413.1 - 1.9 8.1 4.5 0.53 9.8 0.5 2.1 2 0 0 2 2 2 0 BESS motif FUSC_2 PF13515.1 EEQ70414.1 - 6.4e-29 100.4 10.0 6.4e-29 100.4 6.9 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 EEQ70414.1 - 7.5e-08 31.4 11.6 0.0079 14.8 7.0 3.6 4 1 0 4 4 4 2 Aluminium activated malate transporter FUSC PF04632.7 EEQ70414.1 - 0.00042 18.8 15.3 0.03 12.7 5.8 3.5 3 1 0 3 3 3 2 Fusaric acid resistance protein family DUF2421 PF10334.4 EEQ70414.1 - 0.00082 19.0 0.8 0.024 14.2 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) Peptidase_M50 PF02163.17 EEQ70414.1 - 0.005 15.8 0.0 0.0091 14.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M50 DUF1501 PF07394.7 EEQ70414.1 - 0.35 9.6 0.4 0.56 8.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF2422 PF10337.4 EEQ70414.1 - 1 8.0 11.4 0.14 10.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2422) WD40 PF00400.27 EEQ70415.1 - 3.8e-53 175.5 26.0 6e-10 38.6 0.3 11.5 11 0 0 11 11 11 10 WD domain, G-beta repeat eIF2A PF08662.6 EEQ70415.1 - 7.9e-06 25.7 0.2 0.59 9.8 0.0 4.0 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EEQ70415.1 - 0.017 14.7 0.6 12 5.6 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EEQ70415.1 - 0.088 10.6 0.0 5.5 4.6 0.0 2.4 2 1 0 2 2 2 0 IKI3 family Ribosomal_S18 PF01084.15 EEQ70416.1 - 8.3e-13 47.9 0.0 1.7e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 Tox-HNH-HHH PF15637.1 EEQ70416.1 - 0.0093 15.7 0.7 0.31 10.8 0.1 2.3 2 1 0 2 2 2 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif LRS4 PF10422.4 EEQ70416.1 - 0.042 13.2 1.4 0.051 12.9 1.0 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Hormone_1 PF00103.15 EEQ70416.1 - 0.11 11.8 2.7 0.14 11.4 1.6 1.3 1 1 0 1 1 1 0 Somatotropin hormone family HTH_Tnp_Mu_1 PF02316.11 EEQ70416.1 - 0.11 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Mu DNA-binding domain PPR_3 PF13812.1 EEQ70417.1 - 1.5e-14 52.9 0.3 3.4e-05 23.7 0.0 5.8 6 0 0 6 6 6 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 EEQ70417.1 - 7.2e-12 45.0 0.0 0.052 13.5 0.0 6.5 7 0 0 7 7 7 2 PPR repeat family PPR PF01535.15 EEQ70417.1 - 2.3e-07 30.3 0.5 1.2 9.2 0.0 5.8 6 0 0 6 6 6 2 PPR repeat TPR_14 PF13428.1 EEQ70417.1 - 0.00024 21.4 5.0 4.6 8.1 0.0 6.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ70417.1 - 0.0025 18.0 4.5 1.5 9.2 0.2 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat ATP13 PF12921.2 EEQ70417.1 - 0.017 14.5 0.0 0.067 12.5 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ATPase expression Ribosomal_S14 PF00253.16 EEQ70418.1 - 2e-19 68.6 4.4 2.2e-19 68.5 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 EEQ70418.1 - 0.03 14.0 0.5 0.038 13.7 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) DUF2318 PF10080.4 EEQ70418.1 - 0.056 13.2 0.2 0.057 13.1 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) OrfB_Zn_ribbon PF07282.6 EEQ70418.1 - 0.058 13.0 0.3 0.069 12.8 0.2 1.1 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF1451 PF07295.6 EEQ70418.1 - 0.14 11.9 0.3 0.15 11.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) FYVE PF01363.16 EEQ70418.1 - 0.45 10.4 2.9 0.76 9.7 2.0 1.4 1 1 0 1 1 1 0 FYVE zinc finger Prim_Zn_Ribbon PF08273.7 EEQ70418.1 - 0.57 10.3 3.5 7.7 6.6 0.3 2.1 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase DUF4182 PF13790.1 EEQ70418.1 - 0.68 9.7 0.2 0.68 9.7 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4182) Toxin_17 PF08086.6 EEQ70418.1 - 2.8 8.0 6.5 1 9.4 1.0 2.1 1 1 1 2 2 2 0 Ergtoxin family DUF4614 PF15391.1 EEQ70419.1 - 0.33 10.7 2.4 0.38 10.4 1.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) TAF1D PF15333.1 EEQ70419.1 - 0.9 9.2 4.5 1.1 9.0 3.1 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D DUF2201_N PF13203.1 EEQ70419.1 - 2 7.4 6.7 2.4 7.2 4.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF572 PF04502.8 EEQ70419.1 - 8.3 5.5 7.1 9.5 5.3 5.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) ELFV_dehydrog PF00208.16 EEQ70420.1 - 1.7e-58 198.0 0.0 2.7e-58 197.4 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EEQ70420.1 - 2.9e-17 61.5 0.1 6.9e-12 43.6 0.0 2.5 3 0 0 3 3 3 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EEQ70420.1 - 0.025 14.1 0.0 0.061 12.8 0.0 1.6 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NmrA PF05368.8 EEQ70422.1 - 7.3e-27 94.1 0.0 3.9e-26 91.7 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEQ70422.1 - 1.2e-20 74.3 0.1 2e-20 73.5 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEQ70422.1 - 3.2e-05 23.5 0.1 9e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SSP160 PF06933.6 EEQ70424.1 - 0.02 12.9 5.9 0.021 12.8 4.1 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 EEQ70424.1 - 0.1 12.3 4.4 0.13 12.0 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 EEQ70424.1 - 0.23 11.2 10.2 0.26 11.0 7.1 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein TFIIIC_sub6 PF10419.4 EEQ70425.1 - 8.9e-16 57.0 0.5 5.5e-15 54.5 0.0 2.1 2 0 0 2 2 2 1 TFIIIC subunit Mucin PF01456.12 EEQ70425.1 - 9.1 6.0 13.9 8.7 6.1 4.7 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF946 PF06101.6 EEQ70426.1 - 2.9e-13 48.6 0.4 4.4e-13 48.0 0.3 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) DUF1302 PF06980.6 EEQ70426.1 - 0.065 11.8 0.2 0.098 11.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) Cupin_8 PF13621.1 EEQ70427.1 - 1.9e-09 37.4 0.0 4.7e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EEQ70427.1 - 3.7e-09 36.8 0.1 2e-08 34.4 0.0 2.2 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 EEQ70427.1 - 1.8e-07 30.7 4.7 1.8e-07 30.7 3.3 2.6 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.1 EEQ70427.1 - 0.0045 16.2 2.0 0.018 14.3 1.4 2.1 1 0 0 1 1 1 1 PHD-finger Zn_clus PF00172.13 EEQ70427.1 - 0.32 10.9 26.2 0.24 11.3 3.3 3.0 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.17 EEQ70429.1 - 6.1e-19 67.4 0.3 1.1e-18 66.5 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ70429.1 - 9.8e-13 47.8 0.0 1.5e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ70429.1 - 6.3e-10 38.7 0.1 1e-09 38.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3661 PF12400.3 EEQ70430.1 - 4.9e-42 143.0 3.1 6.9e-42 142.5 2.2 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein WD40 PF00400.27 EEQ70431.1 - 6.7e-05 22.6 1.4 0.63 10.0 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat Hexokinase_2 PF03727.11 EEQ70432.1 - 3.9e-84 281.6 0.0 5.4e-84 281.2 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EEQ70432.1 - 3.2e-73 245.4 0.0 4.2e-73 245.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase SIR2 PF02146.12 EEQ70433.1 - 5.1e-55 185.9 0.0 1.1e-54 184.8 0.0 1.5 2 0 0 2 2 2 1 Sir2 family zf-dskA_traR PF01258.12 EEQ70433.1 - 0.016 14.9 0.2 0.045 13.4 0.1 1.8 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger COG4 PF08318.7 EEQ70434.1 - 3.4e-101 338.3 0.0 3e-100 335.2 0.0 2.1 2 0 0 2 2 2 1 COG4 transport protein Ammonium_transp PF00909.16 EEQ70436.1 - 5.4e-112 374.1 30.5 6.3e-112 373.9 21.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family E1-E2_ATPase PF00122.15 EEQ70437.1 - 4.8e-78 261.3 0.0 9e-78 260.4 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEQ70437.1 - 3.4e-46 157.0 0.1 3.4e-46 157.0 0.1 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEQ70437.1 - 5.4e-31 108.6 0.0 9.8e-30 104.5 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEQ70437.1 - 6.3e-22 76.8 0.1 2.2e-21 75.0 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EEQ70437.1 - 2.3e-15 57.2 0.0 6.1e-15 55.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ70437.1 - 2.7e-13 49.6 0.0 5.4e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEQ70437.1 - 1.3e-05 24.9 0.7 0.00022 20.8 0.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.8 EEQ70438.1 - 4.1e-39 132.9 0.2 1.1e-38 131.5 0.0 1.8 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EEQ70438.1 - 4.2e-07 29.0 0.0 8.5e-07 28.0 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EEQ70438.1 - 0.014 14.9 0.1 0.045 13.3 0.0 1.8 2 0 0 2 2 2 0 ScpA/B protein SR-25 PF10500.4 EEQ70439.1 - 0.024 14.0 1.8 0.025 14.0 1.2 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MFS_1 PF07690.11 EEQ70440.1 - 5.7e-36 123.9 41.6 5.7e-36 123.9 28.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ70440.1 - 2.8e-07 29.1 3.6 5e-07 28.2 2.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SPC12 PF06645.8 EEQ70440.1 - 3.4 7.5 9.9 2.6 7.9 0.1 3.8 3 1 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Fijivirus_P9-2 PF06837.6 EEQ70440.1 - 9.4 5.2 6.8 23 4.0 4.7 1.6 1 0 0 1 1 1 0 Fijivirus P9-2 protein Tyrosinase PF00264.15 EEQ70441.1 - 1.5e-54 185.4 1.5 3.5e-54 184.2 1.0 1.6 1 1 0 1 1 1 1 Common central domain of tyrosinase Zn_clus PF00172.13 EEQ70445.1 - 0.0084 16.0 9.2 0.015 15.1 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EEQ70445.1 - 0.04 13.6 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 PAS fold Flavokinase PF01687.12 EEQ70446.1 - 5e-33 113.6 0.0 1.1e-32 112.6 0.0 1.5 1 1 0 1 1 1 1 Riboflavin kinase DUF221 PF02714.10 EEQ70449.1 - 2.9e-109 364.8 29.3 2.9e-109 364.8 20.3 2.0 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EEQ70449.1 - 3.2e-34 117.7 0.2 3.2e-34 117.7 0.2 3.6 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EEQ70449.1 - 1.5e-12 47.2 0.0 5e-12 45.5 0.0 1.9 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EEQ70449.1 - 7.4e-09 36.0 12.0 4.5e-06 27.0 1.3 3.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4463) MCM PF00493.18 EEQ70450.1 - 1.3e-138 461.3 0.0 1.7e-138 460.9 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EEQ70450.1 - 9.8e-26 90.6 0.1 5.6e-25 88.1 0.0 2.3 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEQ70450.1 - 5.4e-06 25.7 0.0 0.00019 20.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEQ70450.1 - 1.2e-05 25.0 0.0 3.2e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EEQ70450.1 - 0.0011 18.5 0.0 0.0046 16.5 0.0 2.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) VTC PF09359.5 EEQ70451.1 - 2e-98 328.8 0.1 2.8e-98 328.4 0.1 1.2 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EEQ70451.1 - 2.4e-29 103.0 4.9 1e-15 58.3 0.0 2.6 3 0 0 3 3 3 2 SPX domain DUF202 PF02656.10 EEQ70451.1 - 1.1e-11 44.8 4.6 2.1e-11 43.8 3.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) 7tm_3 PF00003.17 EEQ70451.1 - 0.086 12.1 1.2 0.13 11.5 0.8 1.1 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR Ribophorin_I PF04597.9 EEQ70452.1 - 8e-142 472.7 0.0 1e-141 472.4 0.0 1.1 1 0 0 1 1 1 1 Ribophorin I Indigoidine_A PF04227.7 EEQ70453.1 - 1.1e-117 392.4 0.3 1.7e-117 391.8 0.2 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EEQ70453.1 - 4.1e-14 52.4 1.8 4.7e-08 32.5 0.1 3.0 2 1 0 2 2 2 2 pfkB family carbohydrate kinase SnoaL PF07366.7 EEQ70454.1 - 8.5e-05 22.1 0.0 0.00028 20.4 0.0 1.8 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EEQ70454.1 - 0.00043 20.6 0.0 0.00086 19.6 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain DLH PF01738.13 EEQ70454.1 - 0.12 11.5 0.0 1.5 8.0 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Ank_2 PF12796.2 EEQ70455.1 - 2.1e-08 34.3 0.0 5.2e-07 29.9 0.0 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ70455.1 - 0.0042 16.8 0.0 0.014 15.2 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 EEQ70455.1 - 0.012 16.1 0.0 4.5 7.9 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ70455.1 - 0.037 14.2 0.2 11 6.4 0.0 3.1 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Methyltransf_11 PF08241.7 EEQ70455.1 - 0.049 14.1 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain UCH_1 PF13423.1 EEQ70458.1 - 1.3 8.3 8.8 1.7 8.0 6.1 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase MCPVI PF02993.9 EEQ70458.1 - 3.9 7.5 8.2 6.4 6.8 5.7 1.4 1 0 0 1 1 1 0 Minor capsid protein VI Pkinase PF00069.20 EEQ70459.1 - 6.7e-21 74.6 0.0 3.2e-20 72.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ70459.1 - 2.6e-12 46.3 0.1 0.00078 18.5 0.0 3.7 4 0 0 4 4 4 3 Protein tyrosine kinase Kdo PF06293.9 EEQ70459.1 - 0.00042 19.4 0.0 0.079 12.0 0.0 2.4 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ70459.1 - 0.063 13.0 0.0 0.31 10.7 0.0 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family DUF1390 PF07150.6 EEQ70460.1 - 0.13 11.6 0.3 0.2 11.0 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1390) DUF928 PF06051.7 EEQ70461.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) Metallophos PF00149.23 EEQ70464.1 - 1.5e-08 34.2 1.2 2.2e-08 33.7 0.9 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEQ70464.1 - 0.0013 18.5 0.2 0.0035 17.2 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ferritin_2 PF13668.1 EEQ70466.1 - 4e-39 133.6 0.2 5.3e-39 133.3 0.2 1.2 1 0 0 1 1 1 1 Ferritin-like domain Band_7 PF01145.20 EEQ70467.1 - 3.3e-23 82.5 3.8 4.8e-23 81.9 2.6 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family CSTF2_hinge PF14327.1 EEQ70468.1 - 1.3e-29 102.0 1.9 1.3e-29 102.0 1.3 2.8 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EEQ70468.1 - 1.6e-19 69.2 0.0 2.6e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EEQ70468.1 - 2e-17 62.2 7.1 6.4e-17 60.5 4.9 2.0 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_6 PF14259.1 EEQ70468.1 - 3.7e-16 58.8 0.0 6.2e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ70468.1 - 5.2e-08 32.6 0.0 7.8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 EEQ70468.1 - 0.053 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein family 7 SNF2_N PF00176.18 EEQ70469.1 - 5e-21 74.7 0.0 4.5e-15 55.2 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 EEQ70469.1 - 1.4e-15 57.3 0.0 3.4e-15 56.0 0.0 1.6 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.26 EEQ70469.1 - 0.00035 20.3 0.0 0.00093 19.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ70469.1 - 0.072 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.1 EEQ70469.1 - 8.9 6.4 26.6 12 6.0 3.2 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) 2Fe-2S_thioredx PF01257.14 EEQ70470.1 - 1.2e-59 200.0 0.1 1.5e-59 199.7 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Sua5_yciO_yrdC PF01300.13 EEQ70472.1 - 1.2e-52 177.7 0.0 2e-52 177.0 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EEQ70472.1 - 2e-25 89.3 0.0 1.3e-24 86.6 0.0 2.2 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding DUF3441 PF11923.3 EEQ70473.1 - 2e-34 117.5 0.0 2e-34 117.5 0.0 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) FbpA PF05833.6 EEQ70473.1 - 5.7e-30 104.2 16.2 2.5e-23 82.3 0.0 2.7 3 0 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EEQ70473.1 - 4.6e-15 55.2 0.0 1.1e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Clat_adaptor_s PF01217.15 EEQ70474.1 - 5.5e-13 48.8 0.0 7.9e-12 45.0 0.0 1.9 2 0 0 2 2 2 1 Clathrin adaptor complex small chain IncA PF04156.9 EEQ70475.1 - 0.0015 18.1 13.4 0.0015 18.1 9.3 3.0 2 1 0 2 2 2 1 IncA protein DUF1515 PF07439.6 EEQ70475.1 - 0.004 16.9 4.2 0.004 16.9 2.9 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1515) Reo_sigmaC PF04582.7 EEQ70475.1 - 0.011 14.9 2.0 0.019 14.1 1.4 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF4613 PF15390.1 EEQ70475.1 - 0.35 9.0 14.1 0.55 8.3 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Z1 PF10593.4 EEQ70475.1 - 0.67 9.1 5.9 1.1 8.3 4.1 1.3 1 0 0 1 1 1 0 Z1 domain DUF948 PF06103.6 EEQ70475.1 - 0.92 9.4 6.4 0.14 12.0 1.4 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MIF4G_like_2 PF09090.6 EEQ70475.1 - 4.3 6.4 12.3 0.69 9.0 5.5 1.9 1 1 0 2 2 2 0 MIF4G like Fib_alpha PF08702.5 EEQ70475.1 - 7 6.7 17.7 2.6 8.1 1.3 3.3 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Ribosomal_L7Ae PF01248.21 EEQ70476.1 - 4.2e-26 90.2 0.0 4.9e-26 90.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SH PF01445.12 EEQ70477.1 - 0.53 9.9 4.5 0.54 9.9 0.1 2.8 2 1 1 3 3 3 0 Viral small hydrophobic protein Ribosomal_L16 PF00252.13 EEQ70478.1 - 1.2e-30 105.9 0.1 1.6e-30 105.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e TPR_1 PF00515.23 EEQ70478.1 - 0.069 12.7 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Lambda_CIII PF02061.11 EEQ70479.1 - 0.045 13.7 0.5 12 5.9 0.0 3.0 3 0 0 3 3 3 0 Lambda Phage CIII F-box PF00646.28 EEQ70480.1 - 1.6e-05 24.4 0.4 0.0066 16.0 0.1 2.8 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.2 EEQ70480.1 - 0.0029 17.2 0.6 0.0082 15.8 0.1 2.1 2 0 0 2 2 2 1 F-box-like HA2 PF04408.18 EEQ70482.1 - 9.8e-20 70.4 0.1 2.1e-19 69.4 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EEQ70482.1 - 4.1e-16 58.8 0.0 9.3e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EEQ70482.1 - 2.7e-12 46.3 0.0 1.5e-11 43.9 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEQ70482.1 - 0.00019 20.9 0.0 0.00072 19.0 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.1 EEQ70482.1 - 0.00087 18.7 0.0 0.0025 17.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain KaiC PF06745.8 EEQ70482.1 - 0.018 14.1 0.0 0.1 11.6 0.0 2.0 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.22 EEQ70482.1 - 0.025 14.8 0.0 0.058 13.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 EEQ70482.1 - 0.043 13.2 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EEQ70482.1 - 0.077 13.1 0.0 0.32 11.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EEQ70482.1 - 0.093 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EEQ70482.1 - 0.1 12.8 0.0 0.47 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain TauD PF02668.11 EEQ70483.1 - 9.2e-26 91.0 0.0 1.2e-25 90.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1157 PF06636.6 EEQ70483.1 - 0.068 11.7 0.0 0.09 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1157) DUF3237 PF11578.3 EEQ70483.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3237) Abhydrolase_6 PF12697.2 EEQ70484.1 - 1.7e-19 70.5 0.0 2.3e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ70484.1 - 0.0056 16.4 0.0 0.0083 15.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EEQ70484.1 - 0.12 11.9 0.1 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Complex1_LYR PF05347.10 EEQ70486.1 - 3.6e-09 36.2 0.1 5.7e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EEQ70486.1 - 2.6e-08 33.9 0.0 3.4e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EEQ70486.1 - 1.6e-05 25.3 0.1 2.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Methyltransf_26 PF13659.1 EEQ70487.1 - 3.5e-17 62.5 0.0 5e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ70487.1 - 0.029 14.8 0.0 0.078 13.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EEQ70487.1 - 0.14 11.5 0.9 5.1 6.4 0.5 2.2 1 1 0 1 1 1 0 Methyltransferase small domain LSM PF01423.17 EEQ70488.1 - 1.8e-16 59.4 0.0 2.4e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEQ70488.1 - 0.00036 20.4 0.0 0.0005 19.9 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2763 PF10961.3 EEQ70488.1 - 0.048 14.0 6.2 0.073 13.4 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) API5 PF05918.6 EEQ70488.1 - 5.2 5.4 12.8 6.7 5.0 8.9 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) GTP_EFTU PF00009.22 EEQ70489.1 - 2e-09 37.1 0.0 3.5e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EEQ70489.1 - 0.14 11.3 0.3 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_35 PF14516.1 EEQ70489.1 - 0.2 10.2 0.2 5.8 5.4 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain ATP_bind_1 PF03029.12 EEQ70489.1 - 0.22 11.0 0.6 2.2 7.7 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein zf-C2H2 PF00096.21 EEQ70491.1 - 3.1e-05 24.0 3.3 0.15 12.4 0.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ70491.1 - 6.8e-05 22.9 4.0 0.017 15.4 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger UPF0547 PF10571.4 EEQ70491.1 - 0.0058 16.2 0.3 0.012 15.3 0.2 1.5 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 zf-H2C2_2 PF13465.1 EEQ70491.1 - 0.091 13.0 0.3 0.3 11.4 0.2 1.9 1 0 0 1 1 1 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 EEQ70491.1 - 0.1 12.5 3.0 9.4 6.2 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Pkr1 PF08636.5 EEQ70493.1 - 5.3e-35 119.3 5.4 6.7e-35 118.9 3.8 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Cullin PF00888.17 EEQ70494.1 - 1.8e-49 168.7 0.0 3.8e-49 167.7 0.0 1.4 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 EEQ70494.1 - 2e-23 82.4 0.0 8.7e-23 80.3 0.0 2.2 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 FeoC PF09012.5 EEQ70494.1 - 0.01 15.5 0.1 0.41 10.4 0.0 2.5 2 0 0 2 2 2 0 FeoC like transcriptional regulator F-box-like PF12937.2 EEQ70495.1 - 8.1e-09 35.0 0.3 2e-08 33.8 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ70495.1 - 2.5e-05 23.8 0.3 6.9e-05 22.3 0.1 1.8 2 0 0 2 2 2 1 F-box domain Mito_carr PF00153.22 EEQ70496.1 - 5.6e-63 208.6 0.1 1.9e-20 72.3 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein SPAN PF02510.9 EEQ70496.1 - 5.7 5.8 8.0 11 4.9 5.6 1.4 1 0 0 1 1 1 0 Surface presentation of antigens protein Zip PF02535.17 EEQ70497.1 - 0.3 10.0 7.9 0.5 9.3 5.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter FAM163 PF15069.1 EEQ70497.1 - 5.5 7.5 9.0 1.9 9.0 3.5 2.3 2 0 0 2 2 2 0 FAM163 family DUF3243 PF11588.3 EEQ70498.1 - 0.15 12.1 0.0 0.73 9.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3243) KAR9 PF08580.5 EEQ70499.1 - 1.7e-125 419.9 0.7 1.7e-125 419.9 0.5 2.4 2 1 1 3 3 3 1 Yeast cortical protein KAR9 Laminin_II PF06009.7 EEQ70499.1 - 0.038 13.7 2.4 11 5.7 0.0 3.9 3 1 1 4 4 4 0 Laminin Domain II Spectrin PF00435.16 EEQ70499.1 - 0.13 12.5 4.3 40 4.5 0.0 3.8 3 1 0 3 3 3 0 Spectrin repeat Cep57_CLD_2 PF14197.1 EEQ70499.1 - 8.7 6.3 7.6 2.6 8.0 0.1 3.0 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Med25_SD1 PF11235.3 EEQ70500.1 - 7.1 6.9 9.2 1.8 8.8 2.4 2.2 2 0 0 2 2 2 0 Mediator complex subunit 25 synapsin 1 Acylphosphatase PF00708.13 EEQ70501.1 - 1.5e-16 60.2 0.0 1.7e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase AOX PF01786.12 EEQ70503.1 - 2.8e-92 307.8 0.1 3.3e-92 307.5 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase MBOAT PF03062.14 EEQ70504.1 - 2.6e-42 145.1 12.6 5e-42 144.1 8.7 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family PufQ PF05398.6 EEQ70504.1 - 0.00058 19.8 0.7 0.41 10.7 0.1 2.5 2 0 0 2 2 2 2 PufQ cytochrome subunit zf-HIT PF04438.11 EEQ70505.1 - 2.7e-10 39.6 7.9 4.1e-10 39.1 5.5 1.3 1 0 0 1 1 1 1 HIT zinc finger DLIC PF05783.6 EEQ70505.1 - 0.26 9.9 2.3 0.34 9.5 1.6 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Dopey_N PF04118.9 EEQ70507.1 - 4.7e-86 288.3 0.1 3.6e-73 246.0 0.0 3.3 2 1 1 3 3 3 2 Dopey, N-terminal Mon1 PF03164.9 EEQ70508.1 - 7.1e-118 393.7 0.0 8.5e-118 393.5 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Helicase_C PF00271.26 EEQ70509.1 - 4.4e-22 77.7 0.3 5.4e-20 71.0 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEQ70509.1 - 7.4e-22 77.6 0.0 2e-21 76.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase RQC PF09382.5 EEQ70509.1 - 2.8e-15 55.9 0.0 1e-14 54.1 0.0 2.0 2 0 0 2 2 2 1 RQC domain HRDC PF00570.18 EEQ70509.1 - 4.4e-09 35.9 0.8 1.4e-08 34.3 0.0 2.3 3 0 0 3 3 3 1 HRDC domain ResIII PF04851.10 EEQ70509.1 - 0.016 15.0 0.0 0.04 13.7 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF3702 PF12486.3 EEQ70509.1 - 0.041 13.5 0.0 0.35 10.5 0.0 2.5 2 0 0 2 2 2 0 ImpA domain protein SecA_DEAD PF07517.9 EEQ70509.1 - 0.082 12.1 0.5 1.9 7.7 0.0 2.3 2 0 0 2 2 2 0 SecA DEAD-like domain DUF4110 PF13422.1 EEQ70510.1 - 9e-31 105.5 0.5 9e-31 105.5 0.3 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.1 EEQ70510.1 - 6.2e-26 89.9 16.8 2e-10 40.5 0.0 6.8 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_4 PF13418.1 EEQ70510.1 - 9.5e-20 70.1 15.4 9.6e-06 25.2 0.0 6.2 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EEQ70510.1 - 2.4e-17 62.4 5.1 1.2e-05 25.0 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 EEQ70510.1 - 1.4e-15 56.7 6.9 0.0017 18.4 0.0 5.5 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 EEQ70510.1 - 3.5e-12 45.5 11.0 9.1e-06 25.2 0.0 6.1 6 1 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 EEQ70510.1 - 2.3e-11 43.0 0.2 0.00013 21.4 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Pyridoxal_deC PF00282.14 EEQ70511.1 - 1.3e-21 76.4 0.0 2.9e-21 75.3 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EEQ70511.1 - 0.0019 17.4 0.0 0.0023 17.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EEQ70511.1 - 0.0056 15.6 0.0 0.009 14.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II MR_MLE_C PF13378.1 EEQ70511.1 - 0.076 12.9 1.8 0.27 11.2 0.0 2.6 3 0 0 3 3 3 0 Enolase C-terminal domain-like Abhydrolase_6 PF12697.2 EEQ70512.1 - 5.3e-11 42.8 0.0 7.5e-10 39.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ70512.1 - 2.7e-09 36.9 0.0 8.2e-09 35.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ70512.1 - 4e-09 36.3 0.0 5.4e-09 35.9 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EEQ70512.1 - 0.059 13.2 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase Esterase PF00756.15 EEQ70512.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative esterase CENP-K PF11802.3 EEQ70513.1 - 0.0003 20.1 3.5 0.088 12.0 0.0 2.9 3 0 0 3 3 3 2 Centromere-associated protein K OmpH PF03938.9 EEQ70513.1 - 4.2 7.2 19.4 6e+02 0.2 13.5 2.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) KH_1 PF00013.24 EEQ70514.1 - 2.8e-39 132.5 5.3 2.8e-16 58.8 0.1 3.5 4 0 0 4 4 4 3 KH domain KH_3 PF13014.1 EEQ70514.1 - 2.6e-30 103.5 10.7 2.3e-11 43.0 1.3 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EEQ70514.1 - 3.7e-10 39.2 2.3 0.014 14.9 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EEQ70514.1 - 0.0011 18.7 5.9 1.3 8.8 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain KH_4 PF13083.1 EEQ70514.1 - 0.0041 16.7 0.2 3.6 7.3 0.0 3.2 3 0 0 3 3 3 1 KH domain TFIIA PF03153.8 EEQ70514.1 - 7.2 6.3 11.8 0.75 9.6 3.1 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Zip PF02535.17 EEQ70515.1 - 0.0006 18.9 1.4 0.0007 18.6 1.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter ABM PF03992.11 EEQ70515.1 - 0.0044 17.0 0.3 0.21 11.6 0.0 3.2 3 0 0 3 3 3 2 Antibiotic biosynthesis monooxygenase SelP_N PF04592.9 EEQ70515.1 - 0.057 12.8 11.5 0.081 12.2 8.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Fungal_trans PF04082.13 EEQ70517.1 - 1.8e-16 59.8 0.0 4.2e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ70517.1 - 1.9e-08 34.0 8.6 3.6e-08 33.1 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 EEQ70518.1 - 0.012 15.4 0.7 7.2 6.6 0.0 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF4618 PF15397.1 EEQ70518.1 - 0.058 12.7 6.3 0.19 11.0 4.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Baculo_PEP_C PF04513.7 EEQ70518.1 - 1.9 8.3 6.1 1.4 8.6 2.3 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Proteasome PF00227.21 EEQ70519.1 - 1.9e-43 147.9 0.0 2.4e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EEQ70519.1 - 1.7e-14 52.7 0.1 3.5e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Peptidase_M3 PF01432.15 EEQ70521.1 - 2.4e-127 425.7 0.0 3.2e-127 425.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 EEQ70521.1 - 0.085 12.2 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Peptidase M50B-like ApoO PF09769.4 EEQ70522.1 - 1e-48 165.0 1.3 4.5e-48 162.9 0.2 1.9 2 0 0 2 2 2 1 Apolipoprotein O DUF3678 PF12435.3 EEQ70522.1 - 0.042 13.4 1.5 0.19 11.3 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) SBF PF01758.11 EEQ70522.1 - 0.047 13.0 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 Sodium Bile acid symporter family GRASP55_65 PF04495.9 EEQ70523.1 - 5e-41 139.9 0.0 1.4e-39 135.2 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain Methyltransf_15 PF09445.5 EEQ70524.1 - 9.9e-50 168.2 0.0 1.3e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 EEQ70524.1 - 7.7e-11 41.8 0.0 1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EEQ70524.1 - 2.6e-09 37.1 0.0 3.8e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EEQ70524.1 - 2.2e-06 27.4 0.0 2.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 EEQ70524.1 - 3.5e-06 26.5 0.0 5.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 EEQ70524.1 - 5.9e-05 23.6 0.0 7.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ70524.1 - 0.0012 18.4 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ70524.1 - 0.018 14.3 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_3 PF01596.12 EEQ70524.1 - 0.023 13.7 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase RrnaAD PF00398.15 EEQ70524.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase LppC PF04348.8 EEQ70524.1 - 0.18 10.2 0.0 4.6 5.6 0.0 2.0 2 0 0 2 2 2 0 LppC putative lipoprotein DUF3591 PF12157.3 EEQ70525.1 - 1.4e-201 669.8 0.6 1.8e-201 669.4 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EEQ70525.1 - 0.0035 16.9 3.2 0.0077 15.8 2.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EEQ70525.1 - 0.014 15.3 0.9 0.025 14.5 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle FlxA PF14282.1 EEQ70525.1 - 0.025 14.5 1.5 0.11 12.4 1.0 2.1 1 0 0 1 1 1 0 FlxA-like protein Pkinase PF00069.20 EEQ70526.1 - 5.2e-49 166.7 1.9 1.1e-24 87.0 0.0 3.3 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ70526.1 - 5.3e-21 74.8 0.1 1.5e-11 43.8 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.18 EEQ70526.1 - 0.0056 16.4 0.3 0.0056 16.4 0.2 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family FKBP_C PF00254.23 EEQ70527.1 - 2.3e-30 104.4 0.0 1.4e-29 101.9 0.0 2.3 2 1 1 3 3 3 1 FKBP-type peptidyl-prolyl cis-trans isomerase CENP-T PF15511.1 EEQ70527.1 - 6.7 5.8 39.5 4.4 6.4 13.7 2.2 1 1 0 2 2 2 0 Centromere kinetochore component CENP-T DUF4551 PF15087.1 EEQ70527.1 - 8.8 4.5 6.5 12 4.1 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) IMS PF00817.15 EEQ70528.1 - 3.8e-42 143.5 0.0 2.2e-41 141.0 0.0 2.2 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EEQ70528.1 - 3e-18 65.9 0.2 9.5e-18 64.3 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 EEQ70528.1 - 2.9e-13 49.6 6.9 5.5e-06 26.2 0.0 3.8 4 0 0 4 4 4 2 Domain of unknown function (DUF4414) BRCT PF00533.21 EEQ70528.1 - 3e-06 27.2 0.0 1.1e-05 25.5 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 EEQ70528.1 - 4.6e-06 26.3 0.2 4.1e-05 23.3 0.0 2.8 3 0 0 3 3 3 1 IMS family HHH motif PTCB-BRCT PF12738.2 EEQ70528.1 - 0.00014 21.5 0.0 0.00045 20.0 0.0 1.9 1 0 0 1 1 1 1 twin BRCT domain HHH_5 PF14520.1 EEQ70528.1 - 0.0013 18.8 0.0 0.0056 16.8 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain F420_ligase PF01996.11 EEQ70528.1 - 0.024 13.6 0.0 0.096 11.7 0.0 2.0 2 0 0 2 2 2 0 F420-0:Gamma-glutamyl ligase DUF1805 PF08827.6 EEQ70528.1 - 0.12 12.1 0.0 0.54 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) DUF4066 PF13278.1 EEQ70530.1 - 2.4e-31 108.2 0.0 2.9e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EEQ70530.1 - 2.8e-11 43.0 0.0 4.2e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 EEQ70530.1 - 0.013 14.9 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Aminotran_1_2 PF00155.16 EEQ70532.1 - 3.9e-67 226.7 0.0 4.6e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II MSC PF09402.5 EEQ70533.1 - 1.7e-102 342.5 0.0 2.2e-102 342.2 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EEQ70533.1 - 9.8e-17 60.2 0.3 4.4e-16 58.1 0.1 2.2 2 0 0 2 2 2 1 HeH/LEM domain DUF3350 PF11830.3 EEQ70533.1 - 0.0034 17.3 0.5 0.12 12.4 0.1 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3350) DUF2630 PF10944.3 EEQ70533.1 - 0.062 13.4 0.3 0.062 13.4 0.2 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2630) PP2C PF00481.16 EEQ70534.1 - 1.1e-54 185.5 0.0 2e-54 184.7 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 EEQ70534.1 - 3.3e-44 147.8 57.9 1.3e-07 31.0 0.5 12.8 6 3 6 13 13 13 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEQ70534.1 - 1.8e-35 120.4 57.0 2.8e-08 33.4 3.9 9.5 6 3 4 11 11 11 9 Leucine rich repeat Guanylate_cyc PF00211.15 EEQ70534.1 - 1.6e-28 99.2 0.0 4.3e-28 97.9 0.0 1.6 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 EEQ70534.1 - 1.1e-17 61.2 60.4 0.28 11.3 0.1 18.3 18 1 2 20 20 19 5 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.6 EEQ70534.1 - 4.4e-13 48.3 0.1 4.4e-13 48.3 0.1 2.3 2 0 0 2 2 2 1 Adenylate cyclase G-alpha binding domain LRR_7 PF13504.1 EEQ70534.1 - 2.3e-07 29.9 53.1 0.67 10.4 0.1 17.3 19 1 1 20 20 19 2 Leucine rich repeat RA PF00788.18 EEQ70534.1 - 4.3e-06 27.1 0.0 1.1e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PP2C_2 PF13672.1 EEQ70534.1 - 0.0047 16.3 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_6 PF13516.1 EEQ70534.1 - 0.0055 16.6 53.9 3.1 8.1 0.1 15.5 17 2 2 19 19 18 3 Leucine Rich repeat LRR_9 PF14580.1 EEQ70534.1 - 0.0061 16.1 10.2 0.25 10.8 0.1 4.0 2 1 1 4 4 4 2 Leucine-rich repeat LRR_5 PF13306.1 EEQ70534.1 - 0.36 10.5 7.2 0.063 12.9 0.4 3.1 4 0 0 4 4 4 0 Leucine rich repeats (6 copies) Calcipressin PF04847.7 EEQ70536.1 - 1.1e-31 109.8 0.5 3.1e-31 108.3 0.0 1.9 2 1 0 2 2 2 1 Calcipressin zf-CGNR PF11706.3 EEQ70537.1 - 2.8 7.5 10.6 0.4 10.2 1.1 2.2 1 1 1 2 2 2 0 CGNR zinc finger Uds1 PF15456.1 EEQ70540.1 - 2.7e-36 124.2 3.5 4.3e-36 123.6 2.4 1.3 1 0 0 1 1 1 1 Up-regulated During Septation DUF4463 PF14703.1 EEQ70540.1 - 0.15 12.6 1.0 0.71 10.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) GrpE PF01025.14 EEQ70541.1 - 1.3e-42 145.1 4.1 1.9e-42 144.6 2.8 1.2 1 0 0 1 1 1 1 GrpE Focal_AT PF03623.8 EEQ70541.1 - 0.074 12.5 0.0 0.19 11.1 0.0 1.7 1 1 0 1 1 1 0 Focal adhesion targeting region DUF3391 PF11871.3 EEQ70541.1 - 0.14 12.4 1.5 0.28 11.3 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) tRNA-synt_2d PF01409.15 EEQ70542.1 - 2.6e-48 164.3 0.2 1.8e-25 89.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EEQ70542.1 - 1.3e-26 92.6 0.0 2.8e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Mito_carr PF00153.22 EEQ70543.1 - 9.4e-57 188.7 0.4 8.6e-20 70.2 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein COX6B PF02297.12 EEQ70544.1 - 8.7e-19 67.3 4.6 1e-18 67.0 3.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 EEQ70544.1 - 0.0029 16.9 0.4 0.0049 16.2 0.3 1.4 1 0 0 1 1 1 1 APOBEC-like C-terminal domain ketoacyl-synt PF00109.21 EEQ70544.1 - 0.14 11.6 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain B12D PF06522.6 EEQ70545.1 - 0.00045 19.8 0.0 0.00079 19.0 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RRM_1 PF00076.17 EEQ70546.1 - 1.1e-15 56.9 0.0 1.6e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ70546.1 - 3e-11 43.1 0.0 4.5e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ70546.1 - 2.1e-08 33.8 0.0 2.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EEQ70546.1 - 0.11 12.3 0.0 0.64 9.8 0.0 2.0 1 1 0 1 1 1 0 RNA binding motif Limkain-b1 PF11608.3 EEQ70546.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 WD40 PF00400.27 EEQ70547.1 - 2.8e-18 65.0 8.3 5.9e-05 22.7 0.1 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat SRA1 PF07304.6 EEQ70547.1 - 2.2e-12 46.9 0.0 7.6e-12 45.2 0.0 2.0 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 EEQ70547.1 - 0.038 13.7 0.5 0.073 12.8 0.4 1.5 1 1 0 1 1 1 0 Sec23-binding domain of Sec16 MBOAT_2 PF13813.1 EEQ70548.1 - 4.1e-20 71.6 7.1 2.4e-14 53.1 1.2 2.6 1 1 0 2 2 2 2 Membrane bound O-acyl transferase family Pex14_N PF04695.8 EEQ70549.1 - 4e-31 107.8 0.1 4e-31 107.8 0.1 2.3 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PAPA-1 PF04795.7 EEQ70550.1 - 2.3e-28 98.7 5.9 2.3e-28 98.7 4.1 2.9 2 0 0 2 2 2 1 PAPA-1-like conserved region Mus7 PF09462.5 EEQ70552.1 - 2.6e-175 584.7 4.0 3.5e-175 584.3 2.7 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family Prismane PF03063.15 EEQ70552.1 - 0.7 8.1 0.0 1.2 7.3 0.0 1.3 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family DUF4050 PF13259.1 EEQ70553.1 - 2.5e-39 133.9 0.0 4e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) AAA PF00004.24 EEQ70554.1 - 2.1e-38 131.4 0.0 2.2e-37 128.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEQ70554.1 - 1e-05 25.7 0.2 0.00051 20.1 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEQ70554.1 - 2.5e-05 24.3 0.1 0.0034 17.4 0.1 3.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EEQ70554.1 - 0.00021 21.0 1.7 0.00067 19.4 0.0 2.7 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EEQ70554.1 - 0.00025 20.1 0.0 0.00056 19.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EEQ70554.1 - 0.00027 20.8 0.0 0.0026 17.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.8 EEQ70554.1 - 0.00047 19.0 0.0 0.00098 17.9 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 EEQ70554.1 - 0.0016 19.2 0.0 0.0065 17.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EEQ70554.1 - 0.0019 18.2 0.0 0.0054 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EEQ70554.1 - 0.0027 17.1 0.3 0.0058 16.0 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EEQ70554.1 - 0.0027 17.4 1.4 0.008 15.9 0.1 2.4 2 0 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 EEQ70554.1 - 0.0034 16.5 0.1 0.0074 15.4 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EEQ70554.1 - 0.0056 16.5 0.0 0.027 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EEQ70554.1 - 0.0068 15.8 0.2 2.9 7.2 0.0 2.3 1 1 1 2 2 2 2 AAA-like domain SHQ1 PF04925.10 EEQ70554.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 SHQ1 protein AAA_25 PF13481.1 EEQ70554.1 - 0.026 13.9 0.2 0.23 10.8 0.1 2.5 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.17 EEQ70554.1 - 0.027 14.6 0.0 0.075 13.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EEQ70554.1 - 0.059 12.9 1.3 0.092 12.3 0.2 1.8 2 0 0 2 2 2 0 AAA domain IPT PF01745.11 EEQ70554.1 - 0.071 12.2 0.0 0.23 10.5 0.0 1.8 2 0 0 2 2 2 0 Isopentenyl transferase Parvo_NS1 PF01057.12 EEQ70554.1 - 0.08 11.8 0.0 0.16 10.8 0.0 1.4 1 1 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 EEQ70554.1 - 0.09 12.4 0.1 0.29 10.7 0.1 1.9 2 0 0 2 2 1 0 NACHT domain AAA_18 PF13238.1 EEQ70554.1 - 0.092 13.0 0.1 0.46 10.7 0.0 2.3 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.21 EEQ70554.1 - 0.2 11.0 0.1 2 7.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Ribosomal_60s PF00428.14 EEQ70554.1 - 1.9 8.9 6.1 0.41 11.0 0.8 2.5 2 0 0 2 2 1 0 60s Acidic ribosomal protein LIM_bind PF01803.11 EEQ70557.1 - 2.2e-69 233.2 0.0 2.2e-69 233.2 0.0 4.3 3 2 1 4 4 4 1 LIM-domain binding protein G-7-MTase PF12803.2 EEQ70557.1 - 7.4 5.6 9.6 32 3.5 6.9 1.8 2 0 0 2 2 2 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) cobW PF02492.14 EEQ70558.1 - 7.2e-35 120.0 0.0 8.7e-35 119.7 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EEQ70558.1 - 4e-07 29.0 0.1 0.014 14.2 0.0 2.0 2 0 0 2 2 2 2 ArgK protein AAA_23 PF13476.1 EEQ70558.1 - 0.0087 16.4 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEQ70558.1 - 0.021 15.6 0.1 0.037 14.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EEQ70558.1 - 0.023 14.3 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.12 EEQ70558.1 - 0.049 13.0 0.1 0.1 12.0 0.0 1.5 2 0 0 2 2 2 0 IstB-like ATP binding protein MMR_HSR1 PF01926.18 EEQ70558.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.1 EEQ70558.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EEQ70558.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EEQ70558.1 - 0.14 10.8 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus BING4CT PF08149.6 EEQ70559.1 - 2.1e-39 132.9 0.0 3.7e-36 122.4 0.0 2.8 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.27 EEQ70559.1 - 0.00015 21.4 0.0 0.064 13.1 0.0 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EEQ70559.1 - 0.058 12.1 0.1 0.32 9.7 0.0 2.1 3 0 0 3 3 3 0 Coatomer WD associated region DUF663 PF04950.7 EEQ70560.1 - 2.8e-97 325.2 0.0 4.3e-97 324.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EEQ70560.1 - 7.6e-25 86.2 0.0 1.5e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 AARP2CN (NUC121) domain MRP-S26 PF14943.1 EEQ70560.1 - 1.1 8.8 8.5 0.024 14.2 0.7 2.0 2 1 0 2 2 2 0 Mitochondrial ribosome subunit S26 DUF726 PF05277.7 EEQ70561.1 - 4e-117 390.9 1.2 6.4e-117 390.3 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 EEQ70561.1 - 5.8e-05 23.0 0.9 9.3e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Glu-tRNAGln PF02686.10 EEQ70561.1 - 0.00015 21.5 5.0 0.00099 18.8 0.7 2.5 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit Thioesterase PF00975.15 EEQ70561.1 - 0.00017 21.8 0.1 0.002 18.3 0.0 2.4 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_5 PF12695.2 EEQ70561.1 - 0.015 15.1 1.0 0.022 14.4 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family SNAP PF14938.1 EEQ70562.1 - 6.4e-115 383.1 18.4 7.2e-115 382.9 12.7 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EEQ70562.1 - 8e-09 35.3 13.9 0.00013 21.7 3.8 3.0 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ70562.1 - 0.0016 18.1 18.1 0.1 12.5 0.1 6.6 3 1 4 7 7 7 1 Tetratricopeptide repeat Exotox-A_target PF09102.5 EEQ70562.1 - 0.007 15.8 0.1 0.013 15.0 0.1 1.4 1 0 0 1 1 1 1 Exotoxin A, targeting TPR_14 PF13428.1 EEQ70562.1 - 0.0074 16.8 13.9 15 6.5 0.9 5.5 1 1 4 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ70562.1 - 0.011 16.4 17.9 1.2 9.8 0.1 3.7 1 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ70562.1 - 0.013 15.0 19.2 0.041 13.5 1.4 4.2 1 1 3 4 4 4 0 TPR repeat TPR_8 PF13181.1 EEQ70562.1 - 0.022 14.4 13.4 0.36 10.7 0.2 5.5 3 2 1 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 EEQ70562.1 - 0.023 14.5 9.6 4.2 7.3 0.1 5.0 5 1 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 EEQ70562.1 - 0.029 14.1 11.2 1.6 8.6 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DFF40 PF09230.5 EEQ70562.1 - 0.039 13.3 0.1 0.077 12.3 0.1 1.5 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa TPR_1 PF00515.23 EEQ70562.1 - 0.054 13.1 17.4 0.3 10.7 0.3 5.8 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ70562.1 - 0.075 12.8 12.7 6.4 6.8 0.0 6.2 6 2 0 6 6 5 0 Tetratricopeptide repeat Sel1 PF08238.7 EEQ70562.1 - 0.1 13.2 10.6 5.8 7.7 0.3 5.1 3 1 2 5 5 5 0 Sel1 repeat TPR_6 PF13174.1 EEQ70562.1 - 0.1 13.0 18.4 1.1 9.8 0.1 6.0 5 1 1 6 6 5 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 EEQ70562.1 - 0.13 11.7 5.0 0.35 10.3 3.5 1.8 1 1 0 1 1 1 0 Foie gras liver health family 1 Apc3 PF12895.2 EEQ70562.1 - 0.29 11.3 10.2 0.19 11.9 1.2 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 NSF PF02071.15 EEQ70562.1 - 6.4 7.8 22.2 3.6 8.5 0.6 6.9 7 0 0 7 7 5 0 Aromatic-di-Alanine (AdAR) repeat Ank PF00023.25 EEQ70563.1 - 2.2e-09 36.6 0.0 1.7e-07 30.7 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 EEQ70563.1 - 5.2e-07 29.9 0.1 1.5e-06 28.4 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EEQ70563.1 - 9.3e-05 22.3 0.0 0.0013 18.7 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EEQ70563.1 - 0.00036 20.9 0.0 0.0022 18.4 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Torsin PF06309.6 EEQ70563.1 - 0.00051 19.9 0.0 0.0015 18.3 0.0 1.8 1 0 0 1 1 1 1 Torsin AAA PF00004.24 EEQ70563.1 - 0.0015 18.7 0.1 0.017 15.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Ank_5 PF13857.1 EEQ70563.1 - 0.079 13.2 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Pyr_redox_2 PF07992.9 EEQ70567.1 - 1.3e-05 25.1 0.0 0.27 11.1 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEQ70567.1 - 4.4e-05 23.6 0.0 0.048 13.7 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEQ70567.1 - 0.0034 17.3 0.0 0.028 14.4 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EEQ70567.1 - 0.063 11.7 0.0 0.25 9.7 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 EEQ70567.1 - 0.13 11.1 0.3 1.3 7.7 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.16 EEQ70567.1 - 0.19 11.2 0.2 20 4.7 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Sec62 PF03839.11 EEQ70569.1 - 2.9e-51 174.0 0.3 2.9e-51 174.0 0.2 1.8 2 0 0 2 2 2 1 Translocation protein Sec62 DUF520 PF04461.8 EEQ70569.1 - 0.096 12.5 1.2 0.16 11.7 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF520) SinI PF08671.5 EEQ70569.1 - 0.13 11.7 0.0 20 4.7 0.0 2.6 2 0 0 2 2 2 0 Anti-repressor SinI Zip PF02535.17 EEQ70569.1 - 0.56 9.1 2.1 19 4.1 0.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter APC_CDC26 PF10471.4 EEQ70569.1 - 7.2 7.4 11.9 4.7 8.0 5.2 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex APC subunit 1 Abhydrolase_6 PF12697.2 EEQ70572.1 - 1.8e-25 90.1 0.1 2.6e-25 89.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ70572.1 - 2.1e-10 40.5 0.1 1.4e-07 31.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ70572.1 - 4.1e-09 36.3 0.0 5.6e-09 35.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EEQ70572.1 - 0.0014 18.9 0.2 0.005 17.0 0.1 2.0 1 1 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 EEQ70572.1 - 0.0018 17.8 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF3089 PF11288.3 EEQ70572.1 - 0.045 12.9 0.1 0.15 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) priB_priC PF07445.7 EEQ70573.1 - 0.0027 17.2 3.2 0.0027 17.2 2.2 1.7 2 0 0 2 2 2 1 Primosomal replication protein priB and priC bZIP_1 PF00170.16 EEQ70573.1 - 0.016 15.1 0.2 0.04 13.8 0.1 1.7 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.10 EEQ70573.1 - 0.11 12.0 0.0 0.11 12.0 0.0 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF2968 PF11180.3 EEQ70573.1 - 1.7 8.0 18.9 0.44 9.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DUF2046 PF09755.4 EEQ70573.1 - 5 5.9 13.6 0.2 10.5 4.8 1.9 3 0 0 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) DUF3138 PF11336.3 EEQ70573.1 - 5.3 5.1 6.2 9.2 4.3 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Carn_acyltransf PF00755.15 EEQ70574.1 - 7.4e-128 427.2 1.6 5e-69 232.9 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase Rxt3 PF08642.5 EEQ70575.1 - 3e-27 95.1 0.0 1.4e-26 92.9 0.0 2.0 1 1 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 EEQ70575.1 - 0.0012 18.8 0.0 0.0028 17.5 0.0 1.6 1 0 0 1 1 1 1 LCCL domain CLN3 PF02487.12 EEQ70576.1 - 1.6e-91 307.0 16.4 5.8e-89 298.6 11.4 3.0 1 1 0 1 1 1 1 CLN3 protein Abhydrolase_3 PF07859.8 EEQ70577.1 - 1.6e-34 119.3 0.0 3.8e-26 91.9 0.0 2.8 2 1 1 3 3 3 2 alpha/beta hydrolase fold Aminotran_3 PF00202.16 EEQ70578.1 - 2.3e-92 309.4 0.0 2.9e-92 309.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EEQ70578.1 - 0.00011 21.3 0.0 0.00019 20.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II DUF1674 PF07896.7 EEQ70579.1 - 4.4e-17 62.0 0.7 8.4e-17 61.1 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) HMGL-like PF00682.14 EEQ70580.1 - 1.8e-37 129.2 0.0 7.3e-37 127.2 0.0 1.8 1 1 0 1 1 1 1 HMGL-like Diphthamide_syn PF01866.12 EEQ70581.1 - 1.7e-113 378.9 0.0 2.1e-113 378.6 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Bromodomain PF00439.20 EEQ70582.1 - 3e-16 59.1 0.0 7.7e-16 57.7 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Uds1 PF15456.1 EEQ70583.1 - 0.0029 17.5 0.7 0.0036 17.2 0.5 1.1 1 0 0 1 1 1 1 Up-regulated During Septation SlyX PF04102.7 EEQ70583.1 - 0.046 14.0 1.2 0.081 13.3 0.8 1.4 1 0 0 1 1 1 0 SlyX Sec2p PF06428.6 EEQ70583.1 - 0.054 13.3 2.1 0.077 12.8 1.5 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Striatin PF08232.7 EEQ70583.1 - 0.079 13.2 1.7 0.1 12.9 1.2 1.2 1 0 0 1 1 1 0 Striatin family DASH_Spc34 PF08657.5 EEQ70583.1 - 0.12 11.9 2.8 0.16 11.6 1.9 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 Herpes_UL25 PF01499.11 EEQ70583.1 - 0.28 9.4 2.6 0.32 9.2 1.8 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family AIRC PF00731.15 EEQ70584.1 - 1.9e-58 196.0 1.0 4.7e-58 194.7 0.7 1.7 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EEQ70584.1 - 3.3e-55 186.0 0.0 5.7e-55 185.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EEQ70584.1 - 2.7e-10 40.2 0.0 6.5e-10 39.0 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EEQ70584.1 - 1e-05 24.9 0.3 2.9e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 EEQ70584.1 - 0.00029 20.2 0.0 0.0056 16.0 0.0 2.4 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EEQ70584.1 - 0.0017 17.1 0.0 0.038 12.7 0.0 2.5 3 0 0 3 3 3 1 ATP-grasp in the biosynthetic pathway with Ter operon PrpR_N PF06506.6 EEQ70584.1 - 0.002 17.5 0.7 0.0098 15.3 0.1 2.3 2 0 0 2 2 2 1 Propionate catabolism activator 2-Hacid_dh_C PF02826.14 EEQ70584.1 - 0.021 13.9 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_binding_2 PF13380.1 EEQ70584.1 - 0.038 14.1 0.4 14 5.8 0.0 3.2 2 1 1 3 3 3 0 CoA binding domain TrkA_N PF02254.13 EEQ70584.1 - 0.04 13.9 0.1 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.10 EEQ70584.1 - 0.059 13.2 0.2 0.18 11.6 0.1 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.1 EEQ70584.1 - 0.064 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain GARS_A PF01071.14 EEQ70584.1 - 0.071 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Shikimate_DH PF01488.15 EEQ70584.1 - 0.092 12.8 0.0 5.3 7.1 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_63 PF03200.11 EEQ70585.1 - 1e-06 26.9 4.3 0.00011 20.2 0.1 3.5 3 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase Neugrin PF06413.6 EEQ70587.1 - 5.8e-11 42.6 0.7 5.8e-11 42.6 0.5 2.2 1 1 1 2 2 2 1 Neugrin MRP-L20 PF12824.2 EEQ70587.1 - 1.1e-06 28.7 12.9 6e-06 26.3 9.0 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_29 PF13551.1 EEQ70587.1 - 0.0052 16.9 0.1 0.011 15.8 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn helix CENP-B_N PF04218.8 EEQ70587.1 - 0.077 12.4 0.6 0.37 10.2 0.0 2.2 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_11 PF08279.7 EEQ70587.1 - 0.084 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 HTH domain Rgp1 PF08737.5 EEQ70588.1 - 1.4e-118 396.6 0.0 2.4e-118 395.8 0.0 1.4 1 0 0 1 1 1 1 Rgp1 Spo0M PF07070.6 EEQ70588.1 - 0.0042 16.4 0.0 0.0081 15.5 0.0 1.4 1 0 0 1 1 1 1 SpoOM protein Arrestin_N PF00339.24 EEQ70588.1 - 0.0053 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain zf-CCHC PF00098.18 EEQ70589.1 - 7.3e-05 22.5 1.5 0.00013 21.7 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle UBN2 PF14223.1 EEQ70589.1 - 0.0023 17.7 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EEQ70589.1 - 0.0069 15.9 0.5 0.016 14.8 0.4 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4432 PF14486.1 EEQ70589.1 - 0.086 11.3 0.0 0.17 10.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) zf-CCHC_4 PF14392.1 EEQ70589.1 - 0.21 11.2 0.9 0.46 10.1 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle Mob1_phocein PF03637.12 EEQ70590.1 - 3.8e-73 244.8 0.1 4.8e-73 244.5 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.13 EEQ70591.1 - 5.4e-42 143.5 3.8 6.8e-42 143.2 2.7 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit vATP-synt_E PF01991.13 EEQ70591.1 - 0.033 13.4 0.3 0.051 12.8 0.2 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit WD40 PF00400.27 EEQ70592.1 - 1.9e-22 78.2 10.2 0.00035 20.3 0.0 8.3 9 0 0 9 9 9 6 WD domain, G-beta repeat SPO22 PF08631.5 EEQ70593.1 - 6.1e-56 189.5 1.3 1.3e-55 188.4 0.9 1.6 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 EEQ70593.1 - 0.057 13.3 0.4 0.057 13.3 0.3 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ70593.1 - 0.14 12.8 0.1 0.14 12.8 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ70593.1 - 0.26 11.2 7.8 0.99 9.4 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SnoaL_2 PF12680.2 EEQ70594.1 - 0.17 12.3 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain CENP-Q PF13094.1 EEQ70595.1 - 4.2e-49 166.6 3.2 4.2e-49 166.6 2.2 1.6 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF904 PF06005.7 EEQ70595.1 - 0.035 14.4 7.8 0.035 14.4 5.4 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF904) GlutR_dimer PF00745.15 EEQ70595.1 - 0.19 11.6 6.5 2.5 8.0 0.1 3.3 3 1 1 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain SbcD_C PF12320.3 EEQ70595.1 - 0.39 10.7 9.2 0.15 12.1 1.9 2.5 3 0 0 3 3 3 0 Type 5 capsule protein repressor C-terminal domain ProSAAS PF07259.7 EEQ70595.1 - 1.8 8.0 9.7 3.7 7.0 0.8 2.1 1 1 1 2 2 2 0 ProSAAS precursor DUF2681 PF10883.3 EEQ70595.1 - 2.5 8.3 6.1 0.95 9.7 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) T2SM PF04612.7 EEQ70595.1 - 3 7.6 10.5 7.8 6.2 4.0 2.6 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein M Spc24 PF08286.6 EEQ70595.1 - 4.9 6.8 10.0 0.45 10.2 2.8 2.3 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 HLH PF00010.21 EEQ70597.1 - 2.5e-07 30.2 0.0 7e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ORC6 PF05460.8 EEQ70597.1 - 0.45 9.5 17.5 0.79 8.7 12.1 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF605 PF04652.11 EEQ70597.1 - 2 7.7 18.9 0.048 13.0 8.3 1.7 2 0 0 2 2 2 0 Vta1 like Cation_ATPase_C PF00689.16 EEQ70598.1 - 0.0026 17.3 0.0 0.0062 16.0 0.0 1.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus CtaG_Cox11 PF04442.9 EEQ70599.1 - 1.5e-58 196.9 0.1 2.1e-58 196.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Rep_fac_C PF08542.6 EEQ70600.1 - 9.8e-14 51.1 0.0 3e-13 49.5 0.0 1.9 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EEQ70600.1 - 1.1e-10 41.4 0.1 2.5e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EEQ70600.1 - 5.6e-06 26.5 0.1 1.1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEQ70600.1 - 8.8e-05 22.6 0.8 0.0005 20.2 0.2 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EEQ70600.1 - 0.0035 17.3 2.1 0.27 11.1 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 EEQ70600.1 - 0.0049 16.7 0.1 0.0089 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain T4SS-DNA_transf PF02534.9 EEQ70600.1 - 0.006 15.2 0.0 0.0095 14.5 0.0 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer AAA_10 PF12846.2 EEQ70600.1 - 0.017 14.5 0.0 0.52 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain Sigma54_activ_2 PF14532.1 EEQ70600.1 - 0.085 12.9 0.2 0.35 10.9 0.1 2.1 1 1 1 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.22 EEQ70600.1 - 0.1 12.9 0.1 0.2 11.9 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Ribosomal_L16 PF00252.13 EEQ70601.1 - 2.7e-33 114.5 1.2 3.8e-33 114.0 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RFC1 PF08519.7 EEQ70602.1 - 2.5e-61 205.9 0.3 1.9e-60 203.1 0.0 2.3 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EEQ70602.1 - 5.9e-13 48.7 0.0 1.5e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EEQ70602.1 - 4.7e-09 36.5 0.2 1.4e-08 34.9 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEQ70602.1 - 1.3e-05 25.3 0.0 4.5e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEQ70602.1 - 6.3e-05 23.7 0.0 0.00036 21.3 0.0 2.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EEQ70602.1 - 0.00063 18.5 0.0 0.014 14.1 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EEQ70602.1 - 0.0023 17.9 0.0 0.032 14.2 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EEQ70602.1 - 0.0025 17.5 0.0 0.0062 16.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EEQ70602.1 - 0.003 17.4 0.0 0.0099 15.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEQ70602.1 - 0.0065 15.5 0.0 0.016 14.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EEQ70602.1 - 0.0075 16.5 0.0 0.031 14.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain PRD_Mga PF08270.6 EEQ70602.1 - 0.029 13.6 0.4 0.049 12.8 0.3 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) PRD domain AAA_14 PF13173.1 EEQ70602.1 - 0.03 14.2 0.0 0.085 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EEQ70602.1 - 0.031 14.2 0.0 0.079 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EEQ70602.1 - 0.072 12.8 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EEQ70602.1 - 0.078 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NAD_binding_8 PF13450.1 EEQ70603.1 - 2.3e-16 59.5 0.0 5.3e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEQ70603.1 - 0.0088 14.9 0.0 0.019 13.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EEQ70603.1 - 0.03 13.3 0.0 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain CHCH PF06747.8 EEQ70605.1 - 4.5e-07 29.6 4.2 9e-07 28.6 2.9 1.5 1 0 0 1 1 1 1 CHCH domain WW PF00397.21 EEQ70605.1 - 0.11 12.3 0.9 0.35 10.7 0.1 2.1 2 0 0 2 2 2 0 WW domain Mito_carr PF00153.22 EEQ70607.1 - 3.8e-61 202.8 4.6 1.7e-20 72.5 0.0 4.4 3 1 1 4 4 4 4 Mitochondrial carrier protein UPF0121 PF03661.8 EEQ70608.1 - 1.4e-10 40.8 1.4 2e-10 40.2 0.9 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Spo7 PF03907.8 EEQ70608.1 - 0.71 9.4 6.8 1.1 8.7 1.1 2.8 2 1 1 3 3 3 0 Spo7-like protein Septin PF00735.13 EEQ70610.1 - 1.4e-123 411.4 0.2 1.4e-123 411.4 0.1 1.9 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EEQ70610.1 - 3.3e-07 30.2 0.0 7.2e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EEQ70610.1 - 9.7e-05 21.6 0.5 0.00098 18.3 0.3 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EEQ70610.1 - 0.00025 21.3 3.7 0.025 14.8 0.0 2.9 2 1 1 3 3 3 1 ABC transporter GTP_EFTU PF00009.22 EEQ70610.1 - 0.00026 20.4 1.9 0.0095 15.3 0.0 3.2 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EEQ70610.1 - 0.0012 18.9 0.2 0.015 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 EEQ70610.1 - 0.0018 17.8 2.4 0.0044 16.4 1.6 2.0 1 1 0 1 1 1 1 AAA-like domain AIG1 PF04548.11 EEQ70610.1 - 0.0027 16.8 1.4 0.0053 15.9 0.0 2.1 2 0 0 2 2 2 1 AIG1 family AAA_22 PF13401.1 EEQ70610.1 - 0.0039 17.3 0.2 0.028 14.5 0.0 2.5 2 2 0 2 2 2 1 AAA domain Ras PF00071.17 EEQ70610.1 - 0.0039 16.5 0.0 0.016 14.6 0.0 2.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ70610.1 - 0.0043 17.5 0.6 0.015 15.7 0.0 2.3 3 0 0 3 3 1 1 Miro-like protein AAA_29 PF13555.1 EEQ70610.1 - 0.0074 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 EEQ70610.1 - 0.012 15.1 0.1 1.8 8.0 0.0 2.9 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 EEQ70610.1 - 0.019 14.4 2.6 0.023 14.2 0.0 2.4 3 0 0 3 3 3 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 EEQ70610.1 - 0.026 14.3 6.5 0.62 9.8 0.0 3.6 4 1 0 4 4 3 0 Dynamin family MobB PF03205.9 EEQ70610.1 - 0.084 12.5 0.1 0.26 10.9 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EEQ70610.1 - 0.1 12.7 0.8 0.61 10.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Phage_GPO PF05929.6 EEQ70610.1 - 0.9 8.7 7.4 1.5 7.9 5.1 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Exonuc_VII_L PF02601.10 EEQ70610.1 - 1.4 8.0 11.1 2.5 7.2 7.2 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit IncA PF04156.9 EEQ70610.1 - 8.4 5.9 8.9 14 5.2 6.2 1.4 1 0 0 1 1 1 0 IncA protein TPK_catalytic PF04263.11 EEQ70611.1 - 4.3e-21 74.7 0.0 1.8e-19 69.5 0.0 2.1 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EEQ70611.1 - 3.8e-17 61.7 0.2 7e-17 60.9 0.1 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Upf2 PF04050.9 EEQ70612.1 - 2.4e-62 209.6 22.8 2.4e-62 209.6 15.8 2.6 3 0 0 3 3 3 1 Up-frameshift suppressor 2 MIF4G PF02854.14 EEQ70612.1 - 1.7e-53 181.1 0.0 5e-26 91.4 0.0 3.5 3 0 0 3 3 3 2 MIF4G domain DUF959 PF06121.9 EEQ70613.1 - 0.58 9.7 5.8 0.69 9.5 4.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF959) DUF566 PF04484.7 EEQ70613.1 - 6.2 6.2 9.5 6.6 6.1 6.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) Glycophorin_A PF01102.13 EEQ70613.1 - 8.1 6.2 7.7 4.3 7.1 3.2 1.8 1 1 1 2 2 2 0 Glycophorin A p450 PF00067.17 EEQ70614.1 - 6.4e-25 87.6 0.0 3.7e-21 75.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Pyr_redox_3 PF13738.1 EEQ70615.1 - 1.7e-19 70.7 0.2 7e-11 42.5 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EEQ70615.1 - 1.8e-15 56.1 0.1 3.2e-09 35.5 0.0 3.3 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EEQ70615.1 - 5.5e-08 32.1 0.0 7.4e-05 21.8 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EEQ70615.1 - 2e-07 30.8 0.0 4.4e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEQ70615.1 - 2.8e-07 30.6 0.0 2.1e-05 24.4 0.0 2.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEQ70615.1 - 9.2e-07 28.0 0.2 0.00053 19.0 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EEQ70615.1 - 2.3e-05 24.4 0.1 0.17 11.9 0.0 3.1 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EEQ70615.1 - 0.00022 21.0 0.1 0.014 15.1 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 EEQ70615.1 - 0.00027 20.1 0.4 0.00071 18.7 0.1 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EEQ70615.1 - 0.0056 15.5 0.2 0.0091 14.8 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 EEQ70615.1 - 0.028 14.6 0.0 1.1 9.4 0.0 2.7 3 0 0 3 3 3 0 Putative NAD(P)-binding FAD_oxidored PF12831.2 EEQ70615.1 - 0.087 11.8 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EEQ70615.1 - 0.18 10.2 0.9 0.33 9.3 0.7 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 EEQ70615.1 - 0.18 10.8 0.3 0.54 9.2 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain Glyco_transf_8 PF01501.15 EEQ70617.1 - 1.3e-24 86.8 0.0 1.7e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 SUN PF03856.8 EEQ70619.1 - 3.9e-99 330.9 9.4 4.8e-99 330.6 6.5 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Ribosomal_L1 PF00687.16 EEQ70620.1 - 8.9e-59 198.4 3.1 1.4e-58 197.8 2.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family TFIIE-A_C-term PF11521.3 EEQ70620.1 - 3.2 7.7 6.5 3 7.8 0.6 2.7 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha ETF PF01012.16 EEQ70621.1 - 3.9e-43 147.0 4.5 4.9e-43 146.6 2.1 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 EEQ70621.1 - 5.8e-35 118.7 0.1 1.3e-34 117.6 0.0 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain AAA PF00004.24 EEQ70624.1 - 2.1e-11 44.1 0.0 4e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEQ70624.1 - 4.1e-06 26.5 0.0 8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEQ70624.1 - 9.6e-06 25.7 0.0 2.4e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ70624.1 - 1.9e-05 24.3 0.0 4.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EEQ70624.1 - 3.1e-05 23.1 0.1 9.4e-05 21.5 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 EEQ70624.1 - 0.00033 19.4 0.0 0.00055 18.7 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EEQ70624.1 - 0.00043 21.0 0.1 0.0016 19.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EEQ70624.1 - 0.00069 19.5 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEQ70624.1 - 0.0014 18.5 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEQ70624.1 - 0.0022 17.9 0.0 0.015 15.2 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 EEQ70624.1 - 0.0028 16.7 0.0 0.0055 15.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NTPase_1 PF03266.10 EEQ70624.1 - 0.027 14.1 0.1 0.094 12.4 0.0 1.9 2 1 0 2 2 2 0 NTPase DUF258 PF03193.11 EEQ70624.1 - 0.033 13.3 0.0 0.063 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EEQ70624.1 - 0.042 13.2 0.0 0.088 12.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 EEQ70624.1 - 0.072 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEQ70624.1 - 0.076 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EEQ70624.1 - 0.15 10.9 0.0 0.28 10.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SWIRM PF04433.12 EEQ70625.1 - 4.2e-34 116.5 0.1 8.4e-34 115.5 0.1 1.5 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EEQ70625.1 - 8.5e-07 28.9 0.1 2.2e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEQ70625.1 - 1e-05 25.5 0.3 3.2e-05 23.9 0.2 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EEQ70625.1 - 0.16 11.5 5.6 0.97 9.0 3.9 2.1 1 1 0 1 1 1 0 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EEQ70626.1 - 0.09 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain ResIII PF04851.10 EEQ70627.1 - 3.8e-24 85.5 0.1 1.3e-23 83.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EEQ70627.1 - 9.1e-15 54.2 0.0 2.3e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEQ70627.1 - 1.4e-09 37.6 0.0 2.6e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 EEQ70627.1 - 0.0025 16.8 0.0 0.0039 16.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EEQ70627.1 - 0.0048 17.0 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain PGAP1 PF07819.8 EEQ70628.1 - 3.4e-81 272.1 0.0 5.2e-81 271.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EEQ70628.1 - 2.9e-06 27.1 0.0 5.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ70628.1 - 0.0001 22.2 0.1 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ70628.1 - 0.0022 17.5 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 EEQ70628.1 - 0.0084 15.4 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 EEQ70628.1 - 0.015 14.2 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF999 PF06198.6 EEQ70628.1 - 0.055 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF999) COesterase PF00135.23 EEQ70628.1 - 0.14 10.8 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family DUF915 PF06028.6 EEQ70628.1 - 0.22 10.5 0.0 0.42 9.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) NAD_binding_10 PF13460.1 EEQ70629.1 - 2.8e-11 43.7 0.0 5.7e-11 42.7 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EEQ70629.1 - 0.0018 17.5 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Cu-oxidase_2 PF07731.9 EEQ70631.1 - 4.1e-43 146.1 4.9 5.5e-40 136.0 0.4 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EEQ70631.1 - 8.8e-31 106.9 0.1 1.8e-30 105.9 0.1 1.5 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EEQ70631.1 - 4.1e-28 97.4 0.5 4.1e-28 97.4 0.3 3.0 3 1 0 3 3 3 1 Multicopper oxidase PX PF00787.19 EEQ70632.1 - 0.027 14.2 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 PX domain MFS_1 PF07690.11 EEQ70633.1 - 0.00068 18.4 7.1 0.0012 17.6 4.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily WD40 PF00400.27 EEQ70638.1 - 3.7e-58 191.4 20.1 1.7e-10 40.3 0.3 7.8 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EEQ70638.1 - 3.4e-14 52.2 0.4 6.9e-14 51.3 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ70638.1 - 8.1e-11 41.2 0.3 2e-10 40.0 0.1 1.8 1 1 0 1 1 1 1 F-box domain Nup160 PF11715.3 EEQ70638.1 - 5.9e-10 37.8 13.2 0.079 11.0 0.1 5.2 2 1 2 4 4 4 4 Nucleoporin Nup120/160 eIF2A PF08662.6 EEQ70638.1 - 0.031 13.9 0.1 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PRANC PF09372.5 EEQ70638.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 PRANC domain Nucleoporin_N PF08801.6 EEQ70638.1 - 0.28 9.8 2.7 10 4.7 0.1 2.6 1 1 1 2 2 2 0 Nup133 N terminal like APG17 PF04108.7 EEQ70639.1 - 7.3e-126 420.2 0.0 8.5e-126 420.0 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Med4 PF10018.4 EEQ70639.1 - 0.0034 16.8 1.4 1.4 8.2 0.1 2.7 2 0 0 2 2 2 2 Vitamin-D-receptor interacting Mediator subunit 4 Snapin_Pallidin PF14712.1 EEQ70639.1 - 0.0043 17.3 0.4 3.8 7.8 0.0 4.1 5 0 0 5 5 4 1 Snapin/Pallidin Tweety PF04906.8 EEQ70639.1 - 0.012 14.0 4.4 0.11 10.8 0.4 2.5 3 0 0 3 3 3 0 Tweety DUF4047 PF13256.1 EEQ70639.1 - 0.046 13.6 0.4 0.26 11.2 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) DUF4358 PF14270.1 EEQ70639.1 - 0.14 12.0 1.3 0.28 11.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) DinB_2 PF12867.2 EEQ70639.1 - 0.33 11.2 3.2 2.7 8.3 0.1 2.9 2 1 0 2 2 2 0 DinB superfamily MCPsignal PF00015.16 EEQ70639.1 - 2.9 7.3 7.2 3.2 7.2 0.7 3.0 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Tup_N PF08581.5 EEQ70639.1 - 4.2 7.6 6.8 30 4.8 0.3 4.1 4 0 0 4 4 4 0 Tup N-terminal IFT20 PF14931.1 EEQ70639.1 - 4.8 7.1 8.2 1.2 9.0 0.1 3.3 4 0 0 4 4 4 0 Intraflagellar transport complex B, subunit 20 COG2 PF06148.6 EEQ70639.1 - 8.2 6.3 8.2 4 7.3 0.5 3.7 3 2 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 RIO1 PF01163.17 EEQ70640.1 - 6.9e-74 247.2 0.0 6.9e-74 247.2 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 EEQ70640.1 - 0.00029 19.9 0.1 0.0049 15.9 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ70640.1 - 0.00044 20.0 0.0 0.079 12.6 0.0 2.5 1 1 0 2 2 2 2 Phosphotransferase enzyme family SMC_N PF02463.14 EEQ70641.1 - 2e-59 200.5 43.5 9.2e-59 198.3 30.2 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EEQ70641.1 - 1.1e-31 109.3 1.9 5.1e-31 107.1 0.1 3.1 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EEQ70641.1 - 1.6e-18 67.7 1.2 6.1e-10 39.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.1 EEQ70641.1 - 9.2e-10 38.1 26.4 7.5e-06 25.2 7.8 3.8 2 2 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 EEQ70641.1 - 7e-07 29.7 45.8 7e-07 29.7 31.7 6.5 2 2 1 3 3 3 1 AAA domain Reo_sigmaC PF04582.7 EEQ70641.1 - 4.6e-05 22.7 27.8 0.046 12.8 0.2 5.5 4 2 1 5 5 5 3 Reovirus sigma C capsid protein AAA_29 PF13555.1 EEQ70641.1 - 0.00032 20.1 0.0 0.00073 19.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 EEQ70641.1 - 0.25 9.7 90.1 0.0092 14.5 10.7 6.7 3 2 3 7 7 7 0 AAA domain ABC_tran PF00005.22 EEQ70641.1 - 0.4 10.9 0.0 0.4 10.9 0.0 6.1 3 2 0 3 3 3 0 ABC transporter DUF87 PF01935.12 EEQ70641.1 - 2.2 8.0 0.0 2.2 8.0 0.0 7.0 3 2 2 5 5 5 0 Domain of unknown function DUF87 DUF3605 PF12239.3 EEQ70642.1 - 2.7e-57 193.0 0.1 3.4e-57 192.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Sif PF06767.6 EEQ70642.1 - 0.067 11.9 0.0 0.09 11.5 0.0 1.1 1 0 0 1 1 1 0 Sif protein FAD_binding_6 PF00970.19 EEQ70643.1 - 3e-30 104.2 0.0 5e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EEQ70643.1 - 4.8e-28 97.8 0.0 8.6e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EEQ70643.1 - 1.3e-05 25.1 0.0 0.0013 18.6 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EEQ70643.1 - 0.00031 20.6 0.0 0.00062 19.7 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF4176 PF13780.1 EEQ70643.1 - 0.078 12.7 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) tRNA-synt_1d PF00750.14 EEQ70644.1 - 2.1e-81 273.5 9.3 1.6e-43 148.9 4.1 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 EEQ70644.1 - 5.9e-28 97.2 0.0 1.6e-27 95.8 0.0 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Med9 PF07544.8 EEQ70644.1 - 0.028 14.1 0.8 0.082 12.6 0.6 1.9 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF948 PF06103.6 EEQ70644.1 - 1 9.2 3.4 31 4.5 0.1 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HSP90 PF00183.13 EEQ70645.1 - 7.9 4.7 15.8 12 4.1 11.0 1.2 1 0 0 1 1 1 0 Hsp90 protein DUF1469 PF07332.6 EEQ70647.1 - 5.4 6.7 6.1 8.9 6.0 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DEAD PF00270.24 EEQ70651.1 - 2.4e-41 141.0 1.0 4.5e-41 140.1 0.7 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ70651.1 - 7.2e-23 80.2 0.1 3.1e-12 46.1 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ70651.1 - 0.00012 22.0 0.1 0.00012 22.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Acyltransferase PF01553.16 EEQ70653.1 - 1.6e-13 50.2 0.0 2.9e-13 49.4 0.0 1.4 1 1 0 1 1 1 1 Acyltransferase L31 PF09784.4 EEQ70654.1 - 1.3e-47 160.1 1.9 1.4e-47 159.9 1.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 SipA PF09052.5 EEQ70654.1 - 0.06 11.7 0.1 0.065 11.6 0.0 1.0 1 0 0 1 1 1 0 Salmonella invasion protein A ZipA_C PF04354.8 EEQ70657.1 - 0.07 12.6 0.0 0.09 12.2 0.0 1.1 1 0 0 1 1 1 0 ZipA, C-terminal FtsZ-binding domain Annexin PF00191.15 EEQ70660.1 - 6.7e-64 211.7 5.2 8.8e-18 63.9 0.0 4.3 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.1 EEQ70660.1 - 0.036 14.2 0.7 16 5.8 0.0 3.1 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 BBE PF08031.7 EEQ70660.1 - 0.086 12.7 0.2 3 7.8 0.0 2.9 3 0 0 3 3 3 0 Berberine and berberine like EBP PF05241.7 EEQ70661.1 - 3.5e-67 225.1 4.2 4.5e-67 224.8 2.9 1.1 1 0 0 1 1 1 1 Emopamil binding protein SH3_9 PF14604.1 EEQ70662.1 - 0.00018 21.0 0.2 0.0004 19.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain ZZ PF00569.12 EEQ70662.1 - 0.0024 17.3 5.4 0.0024 17.3 3.8 2.8 3 0 0 3 3 3 2 Zinc finger, ZZ type DUF2039 PF10217.4 EEQ70662.1 - 0.066 13.2 10.0 1.4 8.9 0.3 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) SH3_1 PF00018.23 EEQ70662.1 - 0.074 12.4 0.1 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 SH3 domain HypA PF01155.14 EEQ70662.1 - 0.2 11.3 12.5 0.12 12.1 0.4 3.2 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family ADH_N PF08240.7 EEQ70662.1 - 0.94 9.2 7.5 8.8 6.1 0.7 2.6 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain CBM_21 PF03370.8 EEQ70664.1 - 4.7e-14 52.3 0.1 1.2e-13 51.0 0.1 1.6 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Histone PF00125.19 EEQ70665.1 - 1.9e-15 56.7 0.3 2.3e-15 56.4 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EEQ70665.1 - 4.9e-05 23.4 0.1 6.6e-05 23.0 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EEQ70665.1 - 7.1e-05 22.6 0.2 0.0001 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EEQ70665.1 - 0.00011 22.2 0.1 0.00019 21.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EEQ70665.1 - 0.0026 17.4 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 EEQ70665.1 - 0.011 14.9 0.0 0.012 14.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID_20kDa PF03847.8 EEQ70665.1 - 0.049 13.9 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Mito_carr PF00153.22 EEQ70666.1 - 7.6e-45 150.5 0.0 6.1e-15 54.7 0.2 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein SIN1 PF05422.7 EEQ70667.1 - 3.2e-34 118.3 1.0 4.3e-21 75.0 0.1 2.3 2 0 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 EEQ70667.1 - 0.024 14.5 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 GLUT4 regulating protein TUG PGA2 PF07543.7 EEQ70667.1 - 3.4 7.4 8.6 0.63 9.8 2.0 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 Pkinase PF00069.20 EEQ70668.1 - 1.2e-68 231.1 0.7 1.6e-68 230.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ70668.1 - 3.4e-37 127.9 0.0 5.2e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ70668.1 - 1.8e-06 27.1 0.0 2.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EEQ70668.1 - 0.084 12.2 0.0 0.084 12.2 0.0 2.5 2 1 0 3 3 3 0 PhoP regulatory network protein YrbL zf-Tim10_DDP PF02953.10 EEQ70669.1 - 2.1e-23 81.3 0.7 2.6e-23 81.0 0.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ins_beta PF03488.9 EEQ70669.1 - 0.021 14.5 0.6 0.041 13.6 0.4 1.4 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type Lectin_leg-like PF03388.8 EEQ70670.1 - 1.4e-64 217.4 0.0 1.8e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family ATG27 PF09451.5 EEQ70670.1 - 0.00014 21.2 0.0 0.00019 20.7 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 27 Lectin_legB PF00139.14 EEQ70670.1 - 0.11 11.8 0.0 0.64 9.3 0.0 2.1 1 1 0 1 1 1 0 Legume lectin domain DUF1777 PF08648.7 EEQ70671.1 - 1.3 8.7 31.3 2.1 8.0 8.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Beta-lactamase PF00144.19 EEQ70672.1 - 4.5e-26 91.6 0.0 1.6e-25 89.8 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase DUF2744 PF10910.3 EEQ70672.1 - 0.13 12.1 0.0 0.42 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2744) PRCC PF10253.4 EEQ70673.1 - 9.7e-49 166.5 4.5 9.7e-49 166.5 3.1 2.2 3 0 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting AAA_5 PF07728.9 EEQ70674.1 - 4.3e-128 421.7 0.0 1.3e-21 76.8 0.0 9.7 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA PF00004.24 EEQ70674.1 - 7.6e-30 103.8 0.3 5.6e-05 23.3 0.0 7.5 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEQ70674.1 - 6.6e-27 94.6 7.3 0.0003 20.8 0.0 8.0 7 0 0 7 7 6 5 AAA ATPase domain AAA_3 PF07726.6 EEQ70674.1 - 7.7e-27 93.4 0.0 1.1e-10 41.2 0.0 7.6 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEQ70674.1 - 2.3e-20 73.0 0.5 0.027 14.6 0.0 8.0 7 0 0 7 7 6 4 AAA domain AAA_17 PF13207.1 EEQ70674.1 - 3.2e-20 73.1 0.0 0.0037 18.0 0.0 7.3 6 0 0 6 6 6 4 AAA domain AAA_14 PF13173.1 EEQ70674.1 - 7.9e-19 67.8 0.0 0.00071 19.4 0.0 7.6 8 0 0 8 8 6 3 AAA domain AAA_33 PF13671.1 EEQ70674.1 - 3.7e-18 65.7 0.2 0.026 14.4 0.0 7.4 6 2 0 6 6 6 3 AAA domain AAA_18 PF13238.1 EEQ70674.1 - 4.7e-17 62.5 0.5 0.025 14.8 0.0 7.4 6 0 0 6 6 6 2 AAA domain Sigma54_activat PF00158.21 EEQ70674.1 - 1.6e-15 56.9 0.0 0.0083 15.6 0.0 6.6 6 0 0 6 6 6 3 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EEQ70674.1 - 2.8e-15 56.5 1.3 0.033 14.2 0.0 7.0 7 0 0 7 7 5 3 Sigma-54 interaction domain ABC_tran PF00005.22 EEQ70674.1 - 3.5e-13 50.0 7.8 0.019 15.2 0.0 7.1 7 0 0 7 7 6 3 ABC transporter Zeta_toxin PF06414.7 EEQ70674.1 - 1.8e-12 46.7 4.4 0.82 8.7 0.0 8.0 8 0 0 8 8 7 3 Zeta toxin NACHT PF05729.7 EEQ70674.1 - 4.2e-12 46.0 6.9 0.094 12.3 0.0 6.2 6 0 0 6 6 6 3 NACHT domain Miro PF08477.8 EEQ70674.1 - 4.2e-12 46.5 2.8 0.33 11.4 0.0 7.3 6 0 0 6 6 6 2 Miro-like protein UPF0079 PF02367.12 EEQ70674.1 - 4.3e-12 45.7 4.4 0.056 13.0 0.0 6.3 6 0 0 6 6 6 3 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 EEQ70674.1 - 1.1e-11 44.2 1.4 1.7 7.7 0.0 8.6 9 0 0 9 9 9 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EEQ70674.1 - 2.4e-11 43.2 5.1 0.13 12.0 0.1 6.4 6 0 0 6 6 6 2 Part of AAA domain SRP54 PF00448.17 EEQ70674.1 - 9e-11 41.5 2.2 0.93 8.8 0.0 6.0 6 0 0 6 6 6 2 SRP54-type protein, GTPase domain T2SE PF00437.15 EEQ70674.1 - 1.3e-10 40.6 6.0 0.032 13.1 0.0 5.7 5 0 0 5 5 5 3 Type II/IV secretion system protein DUF815 PF05673.8 EEQ70674.1 - 2e-10 40.0 1.1 0.034 13.0 0.0 6.0 6 0 0 6 6 6 2 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 EEQ70674.1 - 4.5e-10 39.6 0.2 3.2 7.3 0.0 6.5 6 0 0 6 6 6 0 Archaeal ATPase RNA_helicase PF00910.17 EEQ70674.1 - 5.9e-10 39.2 2.4 1.7 8.8 0.0 7.0 6 0 0 6 6 6 1 RNA helicase DUF258 PF03193.11 EEQ70674.1 - 5.3e-09 35.4 5.0 0.62 9.2 0.1 5.7 6 0 0 6 6 5 3 Protein of unknown function, DUF258 AAA_29 PF13555.1 EEQ70674.1 - 6.3e-09 35.2 1.8 1.7 8.2 0.0 6.6 6 0 0 6 6 6 1 P-loop containing region of AAA domain MobB PF03205.9 EEQ70674.1 - 3.4e-08 33.2 1.3 2.4 7.8 0.0 6.4 6 0 0 6 6 6 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EEQ70674.1 - 3.6e-08 33.0 3.6 0.49 9.7 0.0 6.3 6 0 0 6 6 5 1 AAA domain PduV-EutP PF10662.4 EEQ70674.1 - 5e-08 32.5 3.6 0.27 10.6 0.0 6.2 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EEQ70674.1 - 2.4e-07 30.8 7.1 0.26 11.2 0.0 6.2 6 0 0 6 6 6 2 AAA domain AAA_7 PF12775.2 EEQ70674.1 - 8.4e-07 28.3 0.4 2.9 6.8 0.0 5.3 5 0 0 5 5 5 1 P-loop containing dynein motor region D3 IstB_IS21 PF01695.12 EEQ70674.1 - 1e-06 28.2 0.1 0.37 10.1 0.0 5.1 6 0 0 6 6 5 2 IstB-like ATP binding protein RuvB_N PF05496.7 EEQ70674.1 - 1.7e-06 27.2 3.9 0.27 10.2 0.0 5.9 6 0 0 6 6 6 1 Holliday junction DNA helicase ruvB N-terminus MMR_HSR1 PF01926.18 EEQ70674.1 - 1.7e-05 24.7 0.5 18 5.3 0.0 6.4 7 0 0 7 7 6 0 50S ribosome-binding GTPase Bac_DnaA PF00308.13 EEQ70674.1 - 4.7e-05 23.1 0.0 2.6 7.6 0.0 4.8 5 0 0 5 5 4 1 Bacterial dnaA protein PhoH PF02562.11 EEQ70674.1 - 0.00026 20.2 0.6 6.7 5.8 0.0 4.8 5 0 0 5 5 5 0 PhoH-like protein KaiC PF06745.8 EEQ70674.1 - 0.00032 19.8 0.5 6.9 5.7 0.0 5.6 6 0 0 6 6 6 0 KaiC TIP49 PF06068.8 EEQ70674.1 - 0.00043 19.1 4.7 0.47 9.1 0.0 4.5 5 0 0 5 5 5 1 TIP49 C-terminus Viral_helicase1 PF01443.13 EEQ70674.1 - 0.00049 19.6 0.1 5.5 6.4 0.0 4.9 5 0 0 5 5 5 0 Viral (Superfamily 1) RNA helicase ATP-synt_ab PF00006.20 EEQ70674.1 - 0.00073 19.0 0.2 1.7 8.0 0.0 4.2 5 0 0 5 5 4 1 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.14 EEQ70674.1 - 0.00088 18.7 5.3 6.3 6.2 0.0 5.2 6 0 0 6 6 5 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.1 EEQ70674.1 - 0.0009 18.3 0.0 2.3 7.1 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain ATP_bind_1 PF03029.12 EEQ70674.1 - 0.0016 18.0 6.0 25 4.3 0.0 6.0 7 0 0 7 7 6 0 Conserved hypothetical ATP binding protein CPT PF07931.7 EEQ70674.1 - 0.0016 18.0 3.9 0.85 9.2 0.0 5.3 6 1 0 6 6 4 1 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.10 EEQ70674.1 - 0.0039 16.9 5.8 0.96 9.1 0.0 4.6 5 0 0 5 5 5 1 NTPase MCM PF00493.18 EEQ70674.1 - 0.023 13.4 1.1 10 4.8 0.0 4.4 5 0 0 5 5 5 0 MCM2/3/5 family CbiA PF01656.18 EEQ70674.1 - 0.081 12.3 0.5 1 8.7 0.0 3.0 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Voltage_CLC PF00654.15 EEQ70675.1 - 1.2e-76 258.0 33.4 5.2e-76 255.9 20.7 2.7 2 1 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EEQ70675.1 - 1.4e-06 27.9 0.0 0.0036 17.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain P5CR_dimer PF14748.1 EEQ70676.1 - 4e-33 113.6 2.5 8.4e-33 112.5 1.7 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EEQ70676.1 - 1.8e-12 47.5 1.0 4.8e-10 39.7 0.0 2.7 1 1 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent Pex26 PF07163.7 EEQ70676.1 - 0.047 12.5 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 Pex26 protein CTK3 PF12243.3 EEQ70677.1 - 1.5e-58 196.3 0.5 2.1e-58 195.8 0.4 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EEQ70677.1 - 6.6e-22 77.3 9.2 1.8e-21 75.9 6.4 1.8 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus NAM-associated PF14303.1 EEQ70677.1 - 0.87 9.8 6.4 0.37 11.1 0.6 2.1 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain U3_snoRNA_assoc PF08297.6 EEQ70678.1 - 1.7e-13 50.5 0.1 1.7e-13 50.5 0.1 3.3 4 1 0 4 4 4 1 U3 snoRNA associated EBV-NA3 PF05009.7 EEQ70678.1 - 0.39 9.9 2.2 0.65 9.1 1.5 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CDC45 PF02724.9 EEQ70678.1 - 6.7 4.6 10.4 11 3.9 7.2 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF155 PF02582.9 EEQ70679.1 - 1.7e-52 177.8 0.7 3.7e-52 176.7 0.1 1.7 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Ashwin PF15323.1 EEQ70679.1 - 0.055 13.4 2.1 0.11 12.5 1.4 1.4 1 0 0 1 1 1 0 Developmental protein DUF3253 PF11625.3 EEQ70680.1 - 0.029 14.2 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) HMG_box PF00505.14 EEQ70680.1 - 0.051 13.8 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box Response_reg PF00072.19 EEQ70681.1 - 1.7e-23 82.7 0.1 3.5e-23 81.7 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EEQ70681.1 - 6.9e-23 80.4 0.0 1.2e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 EEQ70681.1 - 1e-21 77.2 0.0 5.7e-12 45.9 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 EEQ70681.1 - 2.4e-17 62.7 0.0 3e-07 30.2 0.0 2.8 3 0 0 3 3 3 2 PAS fold HisKA PF00512.20 EEQ70681.1 - 4e-17 61.9 0.0 1.1e-16 60.5 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.5 EEQ70681.1 - 2.2e-10 40.5 0.0 2.4e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 PAS fold WD40 PF00400.27 EEQ70683.1 - 5.7e-47 155.9 21.5 7.2e-09 35.1 0.2 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EEQ70683.1 - 7e-09 34.3 6.4 0.078 11.0 0.2 4.8 1 1 3 4 4 4 4 Nucleoporin Nup120/160 F-box-like PF12937.2 EEQ70683.1 - 8.8e-06 25.3 0.1 2e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like PQQ_2 PF13360.1 EEQ70683.1 - 0.027 13.9 0.5 1.2 8.5 0.1 2.6 1 1 0 2 2 2 0 PQQ-like domain Zip PF02535.17 EEQ70684.1 - 7.7e-33 113.8 21.9 1.4e-29 103.1 15.2 3.0 1 1 0 1 1 1 1 ZIP Zinc transporter Hat1_N PF10394.4 EEQ70685.1 - 1.4e-46 158.5 0.1 2.1e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus SPX PF03105.14 EEQ70686.1 - 0.75 9.5 4.6 0.17 11.6 0.4 1.8 2 0 0 2 2 2 0 SPX domain LSM PF01423.17 EEQ70687.1 - 1.2e-17 63.2 0.0 1.8e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEQ70687.1 - 0.031 14.1 0.0 0.056 13.3 0.0 1.4 2 0 0 2 2 2 0 Ataxin 2 SM domain API5 PF05918.6 EEQ70687.1 - 3.1 6.1 10.8 3.5 6.0 7.5 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DSPc PF00782.15 EEQ70688.1 - 4.1e-09 36.1 0.0 6.9e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EEQ70688.1 - 0.027 13.8 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EEQ70688.1 - 0.081 13.1 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PPR_2 PF13041.1 EEQ70689.1 - 7.4e-21 73.8 1.7 0.0044 16.9 0.0 7.1 6 2 1 7 7 7 6 PPR repeat family PPR_3 PF13812.1 EEQ70689.1 - 1.3e-12 46.9 2.1 0.012 15.8 0.0 7.6 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR PF01535.15 EEQ70689.1 - 1.9e-09 36.8 14.4 0.12 12.4 0.1 8.0 9 0 0 9 9 9 4 PPR repeat PPR_1 PF12854.2 EEQ70689.1 - 0.07 12.6 4.5 23 4.5 0.0 5.0 5 1 0 5 5 5 0 PPR repeat PLA2_B PF01735.13 EEQ70690.1 - 1.7e-23 82.5 0.0 6.7e-23 80.6 0.0 1.8 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Exo70 PF03081.10 EEQ70691.1 - 7.8e-71 238.8 0.0 4.4e-70 236.3 0.0 1.9 2 0 0 2 2 2 1 Exo70 exocyst complex subunit TPD52 PF04201.10 EEQ70691.1 - 0.0057 16.4 0.2 0.028 14.1 0.0 2.0 2 0 0 2 2 2 1 Tumour protein D52 family BCDHK_Adom3 PF10436.4 EEQ70695.1 - 9.5e-72 239.8 0.0 1.4e-71 239.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EEQ70695.1 - 1.3e-17 63.5 0.0 5.4e-17 61.5 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EEQ70695.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MFS_1 PF07690.11 EEQ70696.1 - 2.4e-08 33.1 43.6 2.7e-06 26.3 11.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Methyltransf_2 PF00891.13 EEQ70697.1 - 7.7e-11 41.6 0.0 8.6e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase SKN1 PF03935.10 EEQ70699.1 - 1e-229 762.8 0.3 1.4e-229 762.4 0.2 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Fructosamin_kin PF03881.9 EEQ70701.1 - 1.8e-58 197.8 0.0 2.4e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EEQ70701.1 - 7.6e-08 32.3 0.0 1.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EEQ70701.1 - 0.038 12.6 0.0 0.056 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Ribosomal_L3 PF00297.17 EEQ70702.1 - 5.7e-120 399.6 8.1 6.6e-120 399.4 5.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 GFA PF04828.9 EEQ70704.1 - 1.2e-05 25.1 0.2 1.2e-05 25.1 0.1 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-CCHC_2 PF13696.1 EEQ70704.1 - 0.19 11.2 0.2 0.19 11.2 0.1 2.2 3 0 0 3 3 3 0 Zinc knuckle TPR_1 PF00515.23 EEQ70707.1 - 8.1e-53 173.9 27.5 4.8e-08 32.2 0.0 10.9 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ70707.1 - 9.1e-48 156.3 19.7 2.3e-06 27.0 0.0 10.6 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ70707.1 - 6.6e-44 147.4 21.2 3.2e-11 42.7 0.6 6.4 2 2 1 6 6 6 5 TPR repeat TPR_8 PF13181.1 EEQ70707.1 - 1.2e-39 131.1 20.1 3.7e-06 26.3 0.0 10.3 8 1 2 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ70707.1 - 1e-32 112.0 8.2 9.9e-08 32.4 0.1 6.5 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ70707.1 - 5.3e-30 103.1 23.5 6.1e-08 32.4 0.3 7.5 3 2 5 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ70707.1 - 5.8e-28 94.8 8.6 7.1e-05 23.0 0.0 9.1 4 3 5 9 9 9 8 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ70707.1 - 4.4e-27 91.9 18.4 0.00053 19.9 0.1 10.4 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ70707.1 - 7e-23 78.5 14.3 0.0033 17.0 0.0 9.8 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ70707.1 - 1.3e-22 79.8 13.7 3.8e-05 23.9 0.0 7.0 5 2 3 8 8 8 6 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ70707.1 - 1.9e-22 78.1 14.7 0.00055 20.2 0.0 10.0 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ70707.1 - 6.7e-13 48.2 10.7 0.0038 17.0 0.1 6.9 2 1 4 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 EEQ70707.1 - 1.8e-12 47.2 13.5 3.9e-08 33.3 2.0 4.2 4 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EEQ70707.1 - 9.1e-10 38.0 9.1 0.00034 19.7 2.1 5.0 1 1 3 4 4 4 4 Tetratricopeptide repeat DUF1777 PF08648.7 EEQ70707.1 - 0.00053 19.7 10.8 0.00053 19.7 7.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) TPR_20 PF14561.1 EEQ70707.1 - 0.0035 17.4 2.4 0.79 9.8 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat DUF2225 PF09986.4 EEQ70707.1 - 0.0095 15.4 4.6 0.43 9.9 0.0 3.5 2 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) Fis1_TPR_C PF14853.1 EEQ70707.1 - 0.023 14.5 0.2 50 3.8 0.0 4.2 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 EEQ70707.1 - 0.17 11.8 13.5 21 5.2 0.1 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_21 PF09976.4 EEQ70707.1 - 0.3 11.0 0.0 0.053 13.4 2.0 4.9 6 1 1 7 7 4 0 Tetratricopeptide repeat MIT PF04212.13 EEQ70707.1 - 0.53 10.2 21.5 0.78 9.6 1.4 5.9 6 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain SNAP PF14938.1 EEQ70707.1 - 0.77 8.8 12.7 27 3.7 0.2 4.6 1 1 2 4 4 4 0 Soluble NSF attachment protein, SNAP SDA1 PF05285.7 EEQ70709.1 - 0.0012 18.1 0.4 0.075 12.3 0.0 2.1 2 0 0 2 2 2 2 SDA1 CENP-B_dimeris PF09026.5 EEQ70709.1 - 0.045 13.9 9.9 0.11 12.7 6.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TFIIA PF03153.8 EEQ70709.1 - 0.22 11.3 28.0 0.013 15.4 9.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.7 EEQ70709.1 - 0.85 9.4 3.0 3.9 7.2 0.0 2.6 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 Nucleoplasmin PF03066.10 EEQ70709.1 - 1.7 8.1 10.4 3.1 7.2 7.2 1.4 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 EEQ70709.1 - 5.1 6.6 8.3 9.7 5.7 5.7 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region NUC173 PF08161.7 EEQ70710.1 - 2.1e-80 268.7 0.2 1.1e-79 266.4 0.1 2.3 3 0 0 3 3 3 1 NUC173 domain HEAT PF02985.17 EEQ70710.1 - 0.3 11.2 1.8 34 4.8 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat LSM PF01423.17 EEQ70711.1 - 0.032 13.7 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 LSM domain PAT1 PF09770.4 EEQ70711.1 - 0.49 8.5 3.1 0.43 8.7 2.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-C2H2_4 PF13894.1 EEQ70712.1 - 0.062 13.6 1.9 0.062 13.6 1.3 2.9 2 1 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EEQ70712.1 - 0.075 13.3 5.2 0.1 12.9 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 EEQ70712.1 - 0.27 11.6 7.4 0.16 12.4 1.7 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF2756 PF10956.3 EEQ70713.1 - 0.015 15.5 0.3 0.02 15.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) Ribonuclease_3 PF00636.21 EEQ70715.1 - 2.1e-40 137.7 0.9 7.8e-19 68.2 0.0 3.1 3 0 0 3 3 3 2 Ribonuclease III domain Dicer_dimer PF03368.9 EEQ70715.1 - 6e-22 77.2 0.0 2e-21 75.5 0.0 1.9 2 0 0 2 2 2 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.1 EEQ70715.1 - 2.3e-20 72.8 0.9 1.5e-09 37.8 0.0 3.9 2 1 0 2 2 2 2 Ribonuclease-III-like DEAD PF00270.24 EEQ70715.1 - 1.2e-17 63.9 0.0 2.5e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ70715.1 - 5.5e-14 51.7 0.1 1.6e-13 50.3 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ70715.1 - 1.9e-10 40.9 0.0 5.5e-10 39.3 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Proteasome PF00227.21 EEQ70716.1 - 1.2e-56 191.0 0.0 2.6e-32 111.6 0.0 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EEQ70716.1 - 1.8e-11 43.1 0.3 4.1e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_S13 PF02113.10 EEQ70716.1 - 0.061 11.8 0.2 0.8 8.1 0.0 2.0 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Methyltransf_2 PF00891.13 EEQ70716.1 - 0.097 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase RINGv PF12906.2 EEQ70717.1 - 2.2e-09 37.1 4.4 5e-09 36.0 0.8 2.3 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 EEQ70717.1 - 0.0054 16.5 4.0 0.016 14.9 0.9 2.2 2 0 0 2 2 2 1 Ring finger domain PhnA_Zn_Ribbon PF08274.7 EEQ70717.1 - 0.12 12.2 0.7 0.34 10.7 0.5 1.8 1 1 0 1 1 1 0 PhnA Zinc-Ribbon PHD PF00628.24 EEQ70717.1 - 4.6 7.0 6.4 1 9.1 2.0 1.7 2 0 0 2 2 2 0 PHD-finger DUF2752 PF10825.3 EEQ70717.1 - 8.8 6.4 6.4 0.46 10.5 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) Aldo_ket_red PF00248.16 EEQ70718.1 - 1.2e-42 145.6 0.0 1.5e-42 145.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 EEQ70720.1 - 2e-09 36.6 2.4 2e-09 36.6 1.7 2.2 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ70720.1 - 9.1e-05 22.2 10.3 0.00015 21.5 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box PF00646.28 EEQ70721.1 - 2.2e-06 27.1 0.6 5.9e-06 25.7 0.4 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EEQ70721.1 - 0.0016 18.1 0.3 0.0016 18.1 0.2 1.8 2 0 0 2 2 2 1 F-box-like MFS_1 PF07690.11 EEQ70722.1 - 8.9e-35 120.0 70.9 4.1e-26 91.5 30.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ70722.1 - 0.0014 17.3 38.8 0.14 10.6 13.5 3.4 2 2 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 EEQ70722.1 - 0.11 12.2 9.0 0.97 9.2 0.8 3.7 4 0 0 4 4 4 0 MFS_1 like family TraT PF05818.7 EEQ70722.1 - 0.75 9.1 3.7 0.52 9.7 0.2 2.2 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Fungal_trans PF04082.13 EEQ70723.1 - 6.1e-15 54.7 0.6 1.1e-14 53.9 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ70723.1 - 3.9e-07 29.8 10.6 8.1e-07 28.8 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EEQ70725.1 - 7.5e-73 245.6 30.7 1.5e-46 158.8 6.6 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EEQ70725.1 - 3.6e-10 39.0 47.1 5.1e-09 35.3 25.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily His_Phos_1 PF00300.17 EEQ70726.1 - 1.6e-25 90.0 0.0 4.7e-25 88.5 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) 6PF2K PF01591.13 EEQ70729.1 - 7e-75 250.9 0.0 9.7e-75 250.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EEQ70729.1 - 1.2e-34 119.6 0.0 2.4e-34 118.6 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EEQ70729.1 - 1.1e-06 28.5 0.0 2.2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EEQ70729.1 - 0.00019 20.7 0.0 0.00029 20.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Vps39_1 PF10366.4 EEQ70730.1 - 5.4e-31 106.8 0.0 1.4e-29 102.2 0.0 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EEQ70730.1 - 1e-30 106.0 0.0 2.8e-30 104.6 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 EEQ70730.1 - 7.5e-18 64.9 0.0 2.1e-17 63.4 0.0 1.7 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.15 EEQ70730.1 - 6.6e-08 32.2 1.2 3.8e-06 26.5 0.4 2.7 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_11 PF13414.1 EEQ70730.1 - 0.035 13.7 1.6 14 5.3 0.0 3.8 3 1 0 3 3 3 0 TPR repeat TPR_16 PF13432.1 EEQ70730.1 - 0.043 14.5 3.1 7 7.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ70730.1 - 0.12 11.9 3.8 30 4.4 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat CLTH PF10607.4 EEQ70730.1 - 0.19 11.4 2.2 2.6 7.7 0.0 2.5 2 0 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain Gon7 PF08738.5 EEQ70731.1 - 4.1e-16 58.8 5.1 2.5e-15 56.3 3.5 1.9 1 1 0 1 1 1 1 Gon7 family DUF4611 PF15387.1 EEQ70731.1 - 0.011 15.8 2.1 0.015 15.4 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Ank_2 PF12796.2 EEQ70732.1 - 5e-89 292.7 23.0 2e-21 76.1 3.3 7.3 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ70732.1 - 4.2e-80 259.8 34.9 3.7e-08 32.7 0.0 14.3 14 0 0 14 14 14 13 Ankyrin repeat Ank_4 PF13637.1 EEQ70732.1 - 1.9e-62 206.6 19.6 1.6e-10 41.1 0.2 8.3 6 2 2 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ70732.1 - 1.3e-58 189.0 26.4 9.5e-05 22.2 0.3 14.6 14 0 0 14 14 14 11 Ankyrin repeat Ank_5 PF13857.1 EEQ70732.1 - 6.1e-56 185.2 25.3 4.1e-08 33.2 0.2 12.5 2 2 9 12 12 12 12 Ankyrin repeats (many copies) HbrB PF08539.6 EEQ70733.1 - 2.5e-53 180.1 0.0 3.9e-53 179.5 0.0 1.3 1 0 0 1 1 1 1 HbrB-like Myb_DNA-bind_6 PF13921.1 EEQ70734.1 - 1.9e-06 27.8 0.8 0.00014 21.9 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EEQ70734.1 - 0.039 13.8 0.5 2.7 7.9 0.0 2.6 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain AAA PF00004.24 EEQ70736.1 - 1.5e-15 57.5 0.0 5.8e-15 55.6 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EEQ70736.1 - 1.8e-05 24.3 0.4 8.1e-05 22.2 0.0 2.3 3 0 0 3 3 3 1 Part of AAA domain AAA_22 PF13401.1 EEQ70736.1 - 0.0006 19.9 0.7 0.016 15.3 0.1 2.8 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EEQ70736.1 - 0.00069 19.3 0.0 0.0021 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MIP-T3 PF10243.4 EEQ70736.1 - 0.002 16.6 52.5 0.0028 16.2 36.4 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 AAA_16 PF13191.1 EEQ70736.1 - 0.073 13.0 0.0 0.073 13.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 EEQ70736.1 - 0.079 12.8 0.1 0.079 12.8 0.0 2.5 2 2 1 3 3 3 0 AAA domain CDC27 PF09507.5 EEQ70736.1 - 1.9 7.6 63.6 3.6 6.7 44.1 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ldh_1_C PF02866.13 EEQ70737.1 - 2.3e-44 151.2 0.0 4.4e-44 150.2 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EEQ70737.1 - 6.7e-43 145.9 0.2 1.3e-42 144.9 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EEQ70737.1 - 0.0025 16.5 0.0 0.0037 16.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 EEQ70737.1 - 0.013 14.5 0.1 0.13 11.3 0.0 2.5 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_4 PF02056.11 EEQ70737.1 - 0.033 13.5 0.2 1.1 8.5 0.2 2.4 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Semialdhyde_dh PF01118.19 EEQ70737.1 - 0.081 13.2 0.2 0.88 9.8 0.0 2.6 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain V-SNARE_C PF12352.3 EEQ70738.1 - 1.1e-08 34.9 0.4 2.9e-08 33.6 0.3 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Hex_IIIa PF02455.11 EEQ70738.1 - 0.018 13.7 0.3 0.025 13.2 0.2 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Lebercilin PF15619.1 EEQ70738.1 - 0.046 13.1 0.3 0.088 12.2 0.2 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease EssA PF10661.4 EEQ70739.1 - 0.23 11.1 2.7 0.2 11.3 0.5 1.8 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA 2-oxoacid_dh PF00198.18 EEQ70740.1 - 6.2e-75 251.4 0.1 8.1e-75 251.0 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EEQ70740.1 - 1.7e-16 59.6 0.7 1.7e-16 59.6 0.5 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EEQ70740.1 - 2.7e-14 52.4 0.6 6.1e-14 51.3 0.4 1.6 1 0 0 1 1 1 1 e3 binding domain Sec7 PF01369.15 EEQ70741.1 - 5.7e-63 212.0 0.7 1.5e-62 210.7 0.1 2.0 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 EEQ70741.1 - 1.5e-54 183.9 7.8 1.5e-54 183.9 5.4 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EEQ70741.1 - 9.6e-30 101.9 2.7 6.2e-29 99.3 0.0 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) NAD_binding_7 PF13241.1 EEQ70742.1 - 5.1e-32 110.2 0.0 7.8e-32 109.6 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EEQ70742.1 - 1.3e-30 104.4 0.0 2.1e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EEQ70742.1 - 1.7e-16 58.8 0.1 2.9e-16 58.1 0.1 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pribosyltran_N PF13793.1 EEQ70743.1 - 5.8e-46 154.9 0.1 1.2e-42 144.2 0.0 2.3 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EEQ70743.1 - 6.1e-32 110.8 0.0 2.2e-27 95.9 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EEQ70743.1 - 1.3e-07 31.4 0.2 2.1e-05 24.2 0.0 2.7 3 0 0 3 3 3 2 Phosphoribosyl transferase domain Phenol_monoox PF04663.7 EEQ70744.1 - 0.21 11.3 0.8 0.62 9.8 0.5 1.8 1 0 0 1 1 1 0 Phenol hydroxylase conserved region p450 PF00067.17 EEQ70747.1 - 6.3e-46 156.8 0.1 3.8e-44 150.9 0.1 2.0 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_10 PF05971.7 EEQ70748.1 - 1.6e-32 112.8 0.0 2.2e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) MTS PF05175.9 EEQ70748.1 - 0.0012 18.2 0.2 0.0048 16.2 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EEQ70748.1 - 0.03 14.3 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ70748.1 - 0.042 14.4 0.0 0.098 13.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain TAF8_C PF10406.4 EEQ70748.1 - 0.83 9.7 3.4 1.8 8.6 2.4 1.6 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term Complex1_LYR PF05347.10 EEQ70749.1 - 7.1e-08 32.1 1.3 1.9e-07 30.7 0.9 1.7 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EEQ70749.1 - 9.3e-08 32.1 2.4 1.1e-07 31.9 0.7 1.9 2 0 0 2 2 2 1 Complex1_LYR-like DAOA PF15199.1 EEQ70749.1 - 0.12 13.0 2.0 0.62 10.7 0.5 2.6 3 0 0 3 3 3 0 D-amino acid oxidase activator Ank_4 PF13637.1 EEQ70750.1 - 6.2e-12 45.7 1.7 1.9e-10 40.9 0.1 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEQ70750.1 - 4.2e-05 23.7 0.2 0.0089 16.3 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEQ70750.1 - 0.00014 21.9 1.1 0.044 14.0 0.1 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Macoilin PF09726.4 EEQ70750.1 - 0.00045 18.6 0.6 0.00045 18.6 0.4 1.5 2 0 0 2 2 2 1 Transmembrane protein KilA-N PF04383.8 EEQ70750.1 - 0.00046 19.7 0.3 0.0026 17.3 0.2 2.2 1 1 0 1 1 1 1 KilA-N domain Ank_3 PF13606.1 EEQ70750.1 - 0.0013 18.7 2.0 0.27 11.5 0.1 4.0 4 1 0 4 4 4 1 Ankyrin repeat HTH_37 PF13744.1 EEQ70750.1 - 0.21 11.4 5.0 3.1 7.6 0.9 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain Phage_GP20 PF06810.6 EEQ70750.1 - 0.74 9.2 5.1 1.4 8.3 2.6 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 Ank PF00023.25 EEQ70750.1 - 2.5 8.0 6.6 4.3 7.3 0.1 3.9 4 1 0 4 4 4 0 Ankyrin repeat Rick_17kDa_Anti PF05433.10 EEQ70751.1 - 8.3e-05 22.1 17.3 0.00016 21.2 12.0 1.5 1 0 0 1 1 1 1 Glycine zipper 2TM domain SR-25 PF10500.4 EEQ70751.1 - 0.019 14.4 16.8 0.025 14.0 11.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Gly-zipper_OmpA PF13436.1 EEQ70751.1 - 0.045 13.4 7.0 0.091 12.4 4.8 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF755 PF05501.6 EEQ70751.1 - 0.21 11.6 21.9 0.28 11.2 15.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF533 PF04391.7 EEQ70751.1 - 0.35 10.2 6.3 0.52 9.6 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) PT-VENN PF04829.8 EEQ70751.1 - 0.4 10.2 3.3 1.1 8.8 2.3 1.7 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Transgly_assoc PF04226.8 EEQ70751.1 - 1.1 9.3 6.4 1.6 8.8 4.4 1.2 1 0 0 1 1 1 0 Transglycosylase associated protein BLVR PF06375.6 EEQ70751.1 - 1.2 8.9 16.0 1.6 8.5 11.1 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Med19 PF10278.4 EEQ70751.1 - 4.6 6.8 13.6 6.9 6.3 9.5 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Bacteriocin_IIc PF10439.4 EEQ70751.1 - 8.9 6.5 15.1 16 5.6 10.4 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF1275 PF06912.6 EEQ70753.1 - 1.6e-34 118.9 1.5 1.8e-34 118.8 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Oxidored_q6 PF01058.17 EEQ70754.1 - 5.9e-22 77.6 0.0 8.2e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit ABC_tran PF00005.22 EEQ70755.1 - 2.4e-46 157.4 0.1 8.2e-24 84.4 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EEQ70755.1 - 1.2e-17 64.8 0.9 0.0015 18.5 0.0 4.3 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EEQ70755.1 - 1.3e-15 57.2 0.0 7.4e-06 25.3 0.0 3.6 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EEQ70755.1 - 2.7e-10 40.9 0.1 0.00011 22.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EEQ70755.1 - 8.3e-10 38.0 0.0 0.0011 18.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EEQ70755.1 - 7.9e-08 31.6 0.0 0.00022 20.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EEQ70755.1 - 2.8e-07 31.3 0.0 0.0034 18.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EEQ70755.1 - 1.7e-06 28.1 0.0 0.017 15.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EEQ70755.1 - 1.8e-06 27.8 0.0 0.02 14.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 EEQ70755.1 - 4.7e-06 26.7 0.0 0.042 14.0 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 EEQ70755.1 - 9.3e-06 25.2 0.0 0.21 10.9 0.0 3.0 3 0 0 3 3 2 2 AAA-like domain AAA_16 PF13191.1 EEQ70755.1 - 1e-05 25.6 0.3 0.47 10.4 0.0 4.2 4 0 0 4 4 4 2 AAA ATPase domain SbcCD_C PF13558.1 EEQ70755.1 - 1.2e-05 25.1 0.1 0.037 13.9 0.0 3.3 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EEQ70755.1 - 1.4e-05 25.4 0.1 0.2 11.9 0.0 3.4 3 0 0 3 3 2 2 AAA domain ArgK PF03308.11 EEQ70755.1 - 1.6e-05 23.8 0.1 0.078 11.7 0.0 2.5 2 0 0 2 2 2 2 ArgK protein NACHT PF05729.7 EEQ70755.1 - 3.5e-05 23.5 0.0 0.039 13.6 0.0 2.7 2 0 0 2 2 2 1 NACHT domain PduV-EutP PF10662.4 EEQ70755.1 - 5.1e-05 22.7 0.0 0.13 11.7 0.0 3.0 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 EEQ70755.1 - 5.2e-05 23.1 0.0 0.57 10.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EEQ70755.1 - 5.4e-05 23.6 0.0 0.094 13.2 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA PF00004.24 EEQ70755.1 - 6.4e-05 23.1 0.0 0.62 10.2 0.0 3.9 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 EEQ70755.1 - 7.2e-05 22.6 0.0 0.0059 16.4 0.0 2.8 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.12 EEQ70755.1 - 0.0001 22.2 1.1 0.21 11.3 0.0 3.1 3 0 0 3 3 2 2 Domain of unknown function DUF87 RNA_helicase PF00910.17 EEQ70755.1 - 0.00014 21.9 0.0 0.66 10.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_13 PF13166.1 EEQ70755.1 - 0.00023 19.8 0.0 1.3 7.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain MobB PF03205.9 EEQ70755.1 - 0.0003 20.5 0.0 0.99 9.1 0.0 2.9 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 EEQ70755.1 - 0.00033 19.8 7.6 0.58 9.1 0.0 4.5 3 2 1 5 5 5 2 AAA ATPase domain AAA_14 PF13173.1 EEQ70755.1 - 0.00061 19.6 0.0 3 7.7 0.0 3.5 4 0 0 4 4 3 1 AAA domain Arch_ATPase PF01637.13 EEQ70755.1 - 0.00064 19.5 0.0 0.61 9.7 0.0 3.0 2 0 0 2 2 2 1 Archaeal ATPase cobW PF02492.14 EEQ70755.1 - 0.0027 17.1 0.2 1.9 7.9 0.0 3.2 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 EEQ70755.1 - 0.003 17.0 0.0 2.9 7.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EEQ70755.1 - 0.0037 16.8 0.0 3.7 7.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 EEQ70755.1 - 0.004 16.6 0.0 4.1 6.8 0.0 2.7 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EEQ70755.1 - 0.0063 16.0 1.9 2.5 7.5 0.0 4.0 4 0 0 4 4 4 1 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 EEQ70755.1 - 0.013 15.0 0.0 4.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein T2SE PF00437.15 EEQ70755.1 - 0.019 13.8 0.0 3.2 6.5 0.0 2.9 2 0 0 2 2 2 0 Type II/IV secretion system protein MutS_V PF00488.16 EEQ70755.1 - 0.024 14.0 0.1 1.4 8.2 0.0 2.4 2 0 0 2 2 2 0 MutS domain V Septin PF00735.13 EEQ70755.1 - 0.026 13.5 0.1 2.5 7.0 0.0 3.0 3 0 0 3 3 3 0 Septin NB-ARC PF00931.17 EEQ70755.1 - 0.027 13.3 0.0 0.55 9.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.1 EEQ70755.1 - 0.034 13.8 0.0 6.1 6.6 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain Mg_chelatase PF01078.16 EEQ70755.1 - 0.059 12.5 0.1 4.6 6.3 0.0 3.1 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEQ70755.1 - 0.091 12.4 0.0 15 5.2 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Optomotor-blind PF11078.3 EEQ70756.1 - 0.024 15.0 2.1 0.029 14.7 0.1 2.2 3 0 0 3 3 3 0 Optomotor-blind protein N-terminal region Baculo_11_kDa PF06143.6 EEQ70757.1 - 0.41 10.0 1.6 0.75 9.1 1.1 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF3357 PF11837.3 EEQ70757.1 - 0.53 10.1 3.1 0.75 9.6 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) TPR_11 PF13414.1 EEQ70758.1 - 2e-10 40.1 2.7 5.4e-07 29.1 0.0 4.8 5 1 1 6 6 6 2 TPR repeat TPR_1 PF00515.23 EEQ70758.1 - 5e-07 29.0 4.2 0.0086 15.6 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ70758.1 - 0.00025 20.9 0.2 1.6 9.1 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ70758.1 - 0.00036 20.2 18.8 0.0042 16.8 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ70758.1 - 0.00045 19.8 2.9 2.8 7.9 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ70758.1 - 0.025 14.3 4.6 3.5 7.6 0.0 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ70758.1 - 0.036 14.7 0.8 0.036 14.7 0.5 5.7 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ70758.1 - 0.052 13.5 17.3 1.2 9.1 0.1 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ70758.1 - 0.068 13.8 0.1 0.068 13.8 0.1 6.0 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ70758.1 - 0.73 9.7 8.9 1.2 8.9 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat SIMPL PF04402.9 EEQ70761.1 - 9.7e-23 81.1 0.1 1.2e-22 80.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) UCH PF00443.24 EEQ70762.1 - 6.1e-79 264.9 0.0 1.6e-78 263.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEQ70762.1 - 3.1e-15 56.3 0.0 2.3e-08 33.8 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EEQ70762.1 - 4.5e-15 55.8 0.0 1.2e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 DUSP domain USP7_C2 PF14533.1 EEQ70762.1 - 0.044 13.2 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal DNA_pol_phi PF04931.8 EEQ70762.1 - 0.26 8.9 0.0 0.47 8.1 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi PX PF00787.19 EEQ70763.1 - 1.2e-18 66.9 0.0 3.9e-18 65.2 0.0 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EEQ70763.1 - 2.4e-10 40.0 7.6 1.6e-05 24.2 0.2 2.1 2 0 0 2 2 2 2 Vps5 C terminal like Noggin PF05806.7 EEQ70763.1 - 0.056 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Noggin Ctr PF04145.10 EEQ70764.1 - 0.4 10.7 5.1 2.1 8.3 3.6 2.2 1 1 0 1 1 1 0 Ctr copper transporter family Shisa PF13908.1 EEQ70765.1 - 0.048 13.8 0.3 0.062 13.4 0.2 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4199 PF13858.1 EEQ70765.1 - 0.078 12.8 0.1 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Ibs_toxin PF13956.1 EEQ70765.1 - 0.12 12.1 1.3 0.2 11.4 0.9 1.3 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system DUF1183 PF06682.7 EEQ70765.1 - 0.3 10.6 5.4 0.59 9.6 3.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) PAT1 PF09770.4 EEQ70765.1 - 1.7 6.8 7.6 1.9 6.6 5.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2428 PF10350.4 EEQ70766.1 - 5.6e-60 202.5 0.0 1.9e-57 194.2 0.0 2.5 1 1 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 EEQ70766.1 - 0.0078 16.2 2.6 2.1 8.6 0.0 5.7 6 0 0 6 6 6 1 HEAT repeat Tim17 PF02466.14 EEQ70767.1 - 3.9e-27 94.8 2.0 4.8e-27 94.5 1.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RecX PF02631.11 EEQ70768.1 - 0.029 14.5 1.7 0.061 13.5 0.0 2.2 3 0 0 3 3 3 0 RecX family DUF3666 PF12408.3 EEQ70768.1 - 0.038 13.0 0.0 0.13 11.3 0.0 1.8 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase EzrA PF06160.7 EEQ70768.1 - 0.042 12.0 0.1 0.071 11.2 0.1 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Pkinase PF00069.20 EEQ70769.1 - 1.5e-27 96.4 0.0 2e-16 59.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ70769.1 - 5.5e-11 42.0 0.0 1.8e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEQ70769.1 - 0.16 10.9 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like ILVD_EDD PF00920.16 EEQ70770.1 - 2.3e-203 676.3 1.3 2.7e-203 676.1 0.9 1.0 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.13 EEQ70770.1 - 0.051 13.5 0.3 1.3 8.9 0.0 3.1 3 1 0 3 3 3 0 5'-nucleotidase, C-terminal domain Lipase_3 PF01764.20 EEQ70771.1 - 9e-22 77.2 0.0 1.7e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EEQ70771.1 - 0.0083 16.0 0.1 0.029 14.2 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EEQ70771.1 - 0.069 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.8 EEQ70771.1 - 0.09 12.3 0.1 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.2 EEQ70771.1 - 0.093 12.4 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 EEQ70771.1 - 0.12 11.7 0.0 0.7 9.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Acyltransferase PF01553.16 EEQ70772.1 - 0.019 14.3 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 Acyltransferase Sugar_tr PF00083.19 EEQ70773.1 - 1.4e-84 284.2 23.7 1.7e-84 284.0 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ70773.1 - 4.8e-16 58.4 33.5 8.1e-16 57.6 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SYS1 PF09801.4 EEQ70773.1 - 0.0029 17.6 0.4 0.0029 17.6 0.3 2.0 2 0 0 2 2 2 1 Integral membrane protein S linking to the trans Golgi network Abhydrolase_6 PF12697.2 EEQ70775.1 - 1.2e-26 94.0 0.3 1.7e-26 93.5 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ70775.1 - 1.3e-22 80.5 0.0 9.5e-19 67.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ70775.1 - 2.7e-10 40.1 0.0 2e-09 37.3 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EEQ70775.1 - 0.00046 18.7 0.0 0.24 9.8 0.0 2.1 2 0 0 2 2 2 2 Ndr family Esterase PF00756.15 EEQ70775.1 - 0.052 12.9 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Kinesin PF00225.18 EEQ70776.1 - 2.6e-104 348.5 0.8 2.6e-104 348.5 0.6 2.1 2 1 0 2 2 2 1 Kinesin motor domain WEMBL PF05701.6 EEQ70776.1 - 0.00045 18.8 23.7 0.00045 18.8 16.4 3.0 2 1 1 3 3 3 2 Weak chloroplast movement under blue light Laminin_I PF06008.9 EEQ70776.1 - 0.0042 16.4 0.1 0.0042 16.4 0.1 4.5 2 1 1 3 3 3 1 Laminin Domain I PKK PF12474.3 EEQ70776.1 - 0.0054 16.4 19.5 0.0054 16.4 13.5 2.8 2 0 0 2 2 2 1 Polo kinase kinase Apolipoprotein PF01442.13 EEQ70776.1 - 0.84 9.1 33.8 0.011 15.3 16.1 2.4 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain DUF972 PF06156.8 EEQ70776.1 - 1.9 8.8 37.9 0.59 10.4 1.9 5.8 3 1 1 5 5 5 0 Protein of unknown function (DUF972) IncA PF04156.9 EEQ70776.1 - 4.5 6.8 50.0 3 7.4 16.0 2.8 2 1 1 3 3 3 0 IncA protein Filament PF00038.16 EEQ70776.1 - 6.9 6.0 45.1 13 5.0 27.2 3.1 2 1 1 3 3 3 0 Intermediate filament protein DUF4239 PF14023.1 EEQ70776.1 - 9.6 5.4 9.1 6.7 6.0 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4239) DUF1900 PF08954.6 EEQ70777.1 - 1.5e-50 170.2 0.0 2e-49 166.5 0.0 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EEQ70777.1 - 1.5e-34 117.4 0.1 2.7e-34 116.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EEQ70777.1 - 1e-23 82.2 2.5 8.7e-07 28.5 0.1 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 EEQ70777.1 - 0.017 13.3 0.1 0.4 8.7 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 eIF2A PF08662.6 EEQ70777.1 - 0.02 14.6 0.0 0.19 11.4 0.0 2.0 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A X PF00739.14 EEQ70778.1 - 0.016 15.1 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Trans-activation protein X HTH_40 PF14493.1 EEQ70778.1 - 0.044 13.9 0.0 0.082 13.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain zf-C3HC4_3 PF13920.1 EEQ70779.1 - 0.0066 16.0 11.1 0.012 15.2 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ70779.1 - 8.9 6.4 12.7 15 5.6 8.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CBFD_NFYB_HMF PF00808.18 EEQ70780.1 - 4.2e-14 52.3 2.8 6.1e-14 51.8 1.9 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEQ70780.1 - 8.1e-06 25.8 1.3 1.2e-05 25.3 0.9 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAT1 PF09770.4 EEQ70780.1 - 6.6 4.8 15.8 6.6 4.8 10.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RAI16-like PF10257.4 EEQ70781.1 - 5.8e-91 305.0 0.0 8e-91 304.5 0.0 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein ABC_tran PF00005.22 EEQ70782.1 - 6.5e-33 113.9 0.0 1.3e-32 113.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EEQ70782.1 - 7.4e-09 35.4 4.1 7.4e-09 35.4 2.8 2.6 2 1 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 EEQ70782.1 - 2.5e-06 26.8 0.1 0.00016 20.9 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEQ70782.1 - 9.4e-05 22.5 0.1 0.085 12.8 0.0 2.3 1 1 1 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EEQ70782.1 - 0.0002 20.5 0.0 0.00037 19.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin DUF258 PF03193.11 EEQ70782.1 - 0.002 17.3 0.0 0.0082 15.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EEQ70782.1 - 0.0036 17.3 0.9 0.0076 16.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.12 EEQ70782.1 - 0.014 15.2 0.2 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF815 PF05673.8 EEQ70782.1 - 0.018 14.0 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.1 EEQ70782.1 - 0.018 15.1 0.0 0.08 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EEQ70782.1 - 0.023 15.5 0.0 0.1 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EEQ70782.1 - 0.026 14.7 0.0 0.51 10.5 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) gpUL132 PF11359.3 EEQ70782.1 - 0.097 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Glycoprotein UL132 MMR_HSR1 PF01926.18 EEQ70782.1 - 0.11 12.5 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 EEQ70782.1 - 0.11 12.0 1.7 0.14 11.7 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Pyr_redox_2 PF07992.9 EEQ70783.1 - 4.4e-06 26.7 0.0 1.4e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ATP1G1_PLM_MAT8 PF02038.11 EEQ70784.1 - 0.037 13.0 0.1 0.093 11.7 0.0 1.7 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family UPF0220 PF05255.6 EEQ70784.1 - 0.05 12.8 0.9 0.071 12.3 0.3 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0220) FAP PF07174.6 EEQ70784.1 - 1.5 8.0 14.6 2.3 7.4 10.1 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) CFEM PF05730.6 EEQ70786.1 - 7.5e-12 44.8 2.7 1.1e-11 44.3 1.9 1.3 1 0 0 1 1 1 1 CFEM domain SOG2 PF10428.4 EEQ70786.1 - 0.93 8.0 11.9 1.2 7.7 8.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein UQ_con PF00179.21 EEQ70788.1 - 2.7e-43 146.7 0.0 2.9e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme QueT PF06177.6 EEQ70789.1 - 1.6 8.7 7.7 5.3 7.0 0.1 2.9 3 0 0 3 3 3 0 QueT transporter Mito_carr PF00153.22 EEQ70790.1 - 1.5e-60 200.9 4.6 6.1e-21 73.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TFIIIC_delta PF12657.2 EEQ70791.1 - 2.3e-48 164.1 0.2 7e-48 162.6 0.1 1.9 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 EEQ70791.1 - 2.1e-34 117.3 3.3 3.9e-34 116.5 2.3 1.4 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex DUF4613 PF15390.1 EEQ70791.1 - 0.14 10.2 1.6 3.9 5.5 0.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4613) DUF2474 PF10617.4 EEQ70792.1 - 0.086 12.4 0.2 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) Glyco_trans_1_4 PF13692.1 EEQ70793.1 - 4.8e-29 101.2 0.1 3.2e-28 98.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EEQ70793.1 - 0.0028 17.7 0.1 0.01 15.9 0.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EEQ70793.1 - 0.026 14.7 0.0 0.049 13.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 Cation_efflux PF01545.16 EEQ70794.1 - 4.4e-50 170.3 11.5 4.4e-50 170.3 8.0 3.6 4 0 0 4 4 4 1 Cation efflux family Zip PF02535.17 EEQ70794.1 - 0.00032 19.7 32.6 0.053 12.5 13.3 3.8 2 2 0 2 2 2 2 ZIP Zinc transporter DUF2946 PF11162.3 EEQ70794.1 - 0.068 13.3 20.4 3 8.0 0.0 4.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2946) Thiolase_N PF00108.18 EEQ70795.1 - 1.4e-95 319.2 1.1 1.8e-95 318.8 0.8 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EEQ70795.1 - 4.6e-37 126.1 3.1 5.2e-37 126.0 0.3 2.3 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EEQ70795.1 - 0.00031 20.3 2.8 0.00089 18.8 0.7 2.4 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Chal_sti_synt_N PF00195.14 EEQ70795.1 - 0.022 13.9 0.2 0.16 11.1 0.0 2.1 2 0 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III PF08545.5 EEQ70795.1 - 0.096 12.3 4.6 4.2 7.1 0.0 3.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UQ_con PF00179.21 EEQ70796.1 - 9.1e-52 174.2 0.0 1e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEQ70796.1 - 3.3e-06 26.8 0.0 3.8e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEQ70796.1 - 0.062 13.2 0.0 0.086 12.7 0.0 1.5 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.18 EEQ70797.1 - 1.1e-110 369.5 0.1 2.7e-110 368.2 0.1 1.7 1 0 0 1 1 1 1 Kinesin motor domain YojJ PF10372.4 EEQ70797.1 - 0.018 14.8 1.0 0.11 12.3 0.7 2.4 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus Peptidase_C1_2 PF03051.10 EEQ70798.1 - 2.4e-160 533.8 0.0 2.9e-160 533.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EEQ70798.1 - 2.1e-06 27.8 0.1 0.0048 16.7 0.1 2.3 2 0 0 2 2 2 2 Papain family cysteine protease His_Phos_1 PF00300.17 EEQ70799.1 - 5.1e-09 36.4 0.0 3.4e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) 5_nucleotid_C PF02872.13 EEQ70800.1 - 2e-37 128.6 0.0 5.7e-37 127.0 0.0 1.7 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EEQ70800.1 - 4.8e-06 26.1 0.2 1.6e-05 24.3 0.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Methyltransf_23 PF13489.1 EEQ70802.1 - 3.2e-15 56.2 0.0 3.6e-12 46.3 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ70802.1 - 1.3e-07 32.1 0.0 5.2e-07 30.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ70802.1 - 3.7e-07 29.8 0.0 2.7e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ70802.1 - 0.00021 21.6 0.0 0.00059 20.2 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 EEQ70802.1 - 0.022 14.7 0.0 0.056 13.4 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF3400 PF11880.3 EEQ70802.1 - 0.028 13.6 0.0 0.062 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) Methyltransf_4 PF02390.12 EEQ70802.1 - 0.03 13.3 0.0 0.084 11.9 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_25 PF13649.1 EEQ70802.1 - 0.033 14.5 0.0 0.074 13.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ70802.1 - 0.037 14.5 0.0 0.18 12.3 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ70802.1 - 0.057 13.4 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EEQ70802.1 - 0.16 11.3 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Sas10_Utp3 PF04000.10 EEQ70803.1 - 2e-14 53.5 0.3 4.1e-14 52.5 0.2 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family CDC45 PF02724.9 EEQ70803.1 - 7.5 4.4 7.5 13 3.6 5.2 1.3 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.11 EEQ70805.1 - 2e-17 62.9 57.6 1e-08 34.3 22.0 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily UFD1 PF03152.9 EEQ70808.1 - 2.8e-70 235.0 0.0 3.5e-70 234.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 EEQ70808.1 - 0.0032 17.0 0.0 0.084 12.5 0.0 2.2 1 1 1 2 2 2 1 Cell division protein 48 (CDC48), domain 2 GYF PF02213.11 EEQ70809.1 - 6.4e-14 51.2 0.3 1.5e-13 50.0 0.2 1.7 1 0 0 1 1 1 1 GYF domain ScpA_ScpB PF02616.9 EEQ70809.1 - 0.061 12.8 4.1 0.1 12.1 2.8 1.3 1 0 0 1 1 1 0 ScpA/B protein TIP49 PF06068.8 EEQ70810.1 - 2.3e-173 576.5 4.4 2.7e-173 576.2 3.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EEQ70810.1 - 6.2e-07 29.6 0.2 0.00052 20.2 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EEQ70810.1 - 4e-06 26.0 1.8 0.0012 17.9 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EEQ70810.1 - 2.9e-05 24.1 0.0 0.00049 20.1 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEQ70810.1 - 7.3e-05 22.9 0.1 0.13 12.4 0.0 2.5 1 1 1 2 2 2 2 AAA domain DnaB_C PF03796.10 EEQ70810.1 - 0.00048 19.0 0.3 0.00078 18.3 0.2 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_14 PF13173.1 EEQ70810.1 - 0.0036 17.1 0.0 2.1 8.2 0.0 2.7 3 0 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EEQ70810.1 - 0.0086 15.5 0.1 2.8 7.3 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.16 EEQ70810.1 - 0.01 14.9 0.9 0.13 11.3 0.3 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEQ70810.1 - 0.048 13.3 0.5 5.2 6.7 0.0 3.2 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) Sipho_tail PF05709.6 EEQ70810.1 - 0.094 11.8 0.1 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Phage tail protein AAA_19 PF13245.1 EEQ70810.1 - 0.11 12.3 0.3 0.33 10.7 0.1 1.9 1 1 0 1 1 1 0 Part of AAA domain Parvo_NS1 PF01057.12 EEQ70810.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Reo_sigmaC PF04582.7 EEQ70811.1 - 9.1e-06 25.0 14.5 9.9e-05 21.6 0.4 2.9 1 1 1 2 2 2 2 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 EEQ70811.1 - 2.9e-05 23.8 1.4 2.9e-05 23.8 1.0 4.1 1 1 3 4 4 4 1 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.7 EEQ70811.1 - 0.0021 17.8 20.2 0.094 12.5 1.7 4.0 1 1 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus TBPIP PF07106.8 EEQ70811.1 - 0.0046 16.5 4.0 0.0046 16.5 2.8 4.2 1 1 4 5 5 5 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 EEQ70811.1 - 0.0051 16.6 19.5 4.4 7.1 0.1 5.2 1 1 4 5 5 5 2 Protein of unknown function (DUF1664) IFT57 PF10498.4 EEQ70811.1 - 0.0052 15.5 26.2 0.2 10.3 2.7 3.1 1 1 2 3 3 3 3 Intra-flagellar transport protein 57 Syntaxin PF00804.20 EEQ70811.1 - 0.0056 16.8 0.6 0.0056 16.8 0.4 4.1 2 1 1 3 3 2 2 Syntaxin IncA PF04156.9 EEQ70811.1 - 0.0082 15.7 33.2 0.013 15.1 2.2 3.5 1 1 2 3 3 3 1 IncA protein Bacillus_HBL PF05791.6 EEQ70811.1 - 0.029 13.7 0.7 0.029 13.7 0.5 3.3 3 1 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Fib_alpha PF08702.5 EEQ70811.1 - 0.032 14.3 23.6 0.12 12.5 2.4 4.0 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family HsbA PF12296.3 EEQ70811.1 - 0.044 13.6 3.2 1.2 9.0 0.3 3.2 2 1 0 2 2 2 0 Hydrophobic surface binding protein A FliD_N PF02465.13 EEQ70811.1 - 0.053 13.8 0.4 0.053 13.8 0.2 4.5 1 1 3 4 4 4 0 Flagellar hook-associated protein 2 N-terminus Abi_C PF14355.1 EEQ70811.1 - 0.14 12.0 1.6 4.4 7.2 0.0 3.4 4 0 0 4 4 3 0 Abortive infection C-terminus Prominin PF05478.6 EEQ70811.1 - 0.15 9.5 17.2 0.4 8.1 2.8 2.5 2 0 0 2 2 2 0 Prominin DUF948 PF06103.6 EEQ70811.1 - 0.21 11.4 8.7 1.8 8.4 0.1 4.4 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) IFT20 PF14931.1 EEQ70811.1 - 0.25 11.2 0.2 0.25 11.2 0.1 4.6 2 2 2 5 5 5 0 Intraflagellar transport complex B, subunit 20 DUF2509 PF10713.4 EEQ70811.1 - 0.28 10.9 2.8 0.26 11.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2509) Nup54 PF13874.1 EEQ70811.1 - 0.3 10.7 29.2 0.26 10.9 6.0 4.4 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 Hemerythrin PF01814.18 EEQ70811.1 - 0.33 11.0 12.2 0.17 12.0 0.9 4.2 2 2 1 3 3 3 0 Hemerythrin HHE cation binding domain Fzo_mitofusin PF04799.8 EEQ70811.1 - 0.48 9.7 22.2 2.4 7.5 0.5 5.0 2 1 3 5 5 5 0 fzo-like conserved region ATG16 PF08614.6 EEQ70811.1 - 1.1 9.0 34.2 0.92 9.3 2.8 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF972 PF06156.8 EEQ70811.1 - 1.1 9.6 23.9 3.1 8.2 2.4 4.9 1 1 4 5 5 5 0 Protein of unknown function (DUF972) WXG100 PF06013.7 EEQ70811.1 - 1.3 9.0 15.6 1.1 9.3 0.7 5.5 4 2 0 4 4 4 0 Proteins of 100 residues with WXG BLOC1_2 PF10046.4 EEQ70811.1 - 1.4 9.1 21.5 3.9 7.6 0.2 5.2 2 2 4 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cep57_CLD_2 PF14197.1 EEQ70811.1 - 1.4 8.8 29.5 0.67 9.9 4.3 5.0 3 2 1 4 4 4 0 Centrosome localisation domain of PPC89 DUF2730 PF10805.3 EEQ70811.1 - 2 8.2 13.2 0.57 9.9 0.4 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF2730) APG6 PF04111.7 EEQ70811.1 - 3.7 6.5 30.5 1.3 8.0 4.7 3.3 1 1 2 3 3 3 0 Autophagy protein Apg6 Spectrin PF00435.16 EEQ70811.1 - 6.6 7.0 23.9 0.14 12.4 2.3 4.2 1 1 0 3 3 3 0 Spectrin repeat NPV_P10 PF05531.7 EEQ70811.1 - 7 6.9 20.1 11 6.4 0.4 5.0 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein Med9 PF07544.8 EEQ70811.1 - 7 6.4 22.6 0.55 9.9 1.4 4.7 4 1 1 5 5 5 0 RNA polymerase II transcription mediator complex subunit 9 ORC6 PF05460.8 EEQ70814.1 - 1 8.3 6.6 1.3 8.0 4.6 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Dicty_REP PF05086.7 EEQ70814.1 - 4.3 4.9 6.4 5.3 4.6 4.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Abp2 PF09441.5 EEQ70815.1 - 2e-77 259.0 0.1 4.3e-77 257.9 0.0 1.5 1 0 0 1 1 1 1 ARS binding protein 2 ORC6 PF05460.8 EEQ70816.1 - 0.12 11.4 5.8 0.14 11.2 4.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Sigma70_r4_2 PF08281.7 EEQ70817.1 - 0.045 13.2 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Mga PF08280.6 EEQ70817.1 - 0.063 13.0 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain DUF4396 PF14342.1 EEQ70820.1 - 1.3e-47 161.3 4.5 2.3e-47 160.5 3.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) F-box-like PF12937.2 EEQ70821.1 - 0.016 14.9 0.6 0.043 13.5 0.4 1.8 1 0 0 1 1 1 0 F-box-like WW PF00397.21 EEQ70822.1 - 4.7e-06 26.3 1.4 9.8e-06 25.3 1.0 1.6 1 0 0 1 1 1 1 WW domain Brix PF04427.13 EEQ70823.1 - 1.1e-28 100.2 0.0 1.4e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain PBP1_TM PF14812.1 EEQ70823.1 - 1.7 8.9 6.9 0.86 9.9 1.7 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EndIII_4Fe-2S PF10576.4 EEQ70824.1 - 4.3 7.6 6.3 1.2 9.4 0.2 3.1 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Pga1 PF10333.4 EEQ70826.1 - 0.036 13.7 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 GPI-Mannosyltransferase II co-activator FPN1 PF06963.7 EEQ70826.1 - 0.13 10.6 0.2 0.22 9.8 0.1 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Tubulin PF00091.20 EEQ70827.1 - 1e-70 237.9 0.0 1.5e-70 237.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EEQ70827.1 - 4.6e-50 168.8 0.2 8.5e-50 168.0 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EEQ70827.1 - 0.0025 17.2 0.0 0.0051 16.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain EF-hand_4 PF12763.2 EEQ70828.1 - 2.8e-37 126.6 0.0 1.1e-14 54.0 0.0 3.6 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EEQ70828.1 - 9.1e-11 41.7 0.0 8.4e-06 25.8 0.0 4.0 4 0 0 4 4 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EEQ70828.1 - 8.3e-08 30.9 0.0 0.0024 17.0 0.0 4.8 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.1 EEQ70828.1 - 5.9e-05 22.6 0.2 0.005 16.4 0.0 3.1 3 0 0 3 3 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EEQ70828.1 - 0.0001 21.8 0.7 3.3 7.8 0.0 5.1 5 0 0 5 5 5 1 EF-hand domain DUF812 PF05667.6 EEQ70828.1 - 0.00014 20.5 5.7 0.00029 19.5 4.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) UBA PF00627.26 EEQ70828.1 - 0.00031 20.4 0.0 0.00068 19.4 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain ATG16 PF08614.6 EEQ70828.1 - 0.0068 16.2 5.6 0.0068 16.2 3.9 2.5 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Myosin_tail_1 PF01576.14 EEQ70828.1 - 0.0075 14.0 20.5 0.011 13.5 14.2 1.1 1 0 0 1 1 1 1 Myosin tail AAA_13 PF13166.1 EEQ70828.1 - 0.027 12.9 11.6 0.042 12.3 8.1 1.2 1 0 0 1 1 1 0 AAA domain GAS PF13851.1 EEQ70828.1 - 0.094 11.9 13.6 0.18 10.9 9.4 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 EEQ70828.1 - 0.098 12.4 20.4 0.15 11.7 13.0 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF960 PF06124.6 EEQ70828.1 - 0.16 12.2 0.0 85 3.5 0.0 3.3 3 0 0 3 3 3 0 Staphylococcal protein of unknown function (DUF960) Spc7 PF08317.6 EEQ70828.1 - 0.27 9.8 18.2 0.079 11.6 3.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Syntaxin PF00804.20 EEQ70828.1 - 0.38 10.9 0.0 0.38 10.9 0.0 3.4 2 1 1 3 3 3 0 Syntaxin ERM PF00769.14 EEQ70828.1 - 0.48 9.9 16.0 0.012 15.1 6.1 2.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family IncA PF04156.9 EEQ70828.1 - 0.56 9.7 24.0 0.3 10.6 14.9 1.7 1 1 1 2 2 2 0 IncA protein CENP-Q PF13094.1 EEQ70828.1 - 0.61 10.0 20.6 3.5 7.6 13.5 2.4 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4201 PF13870.1 EEQ70828.1 - 0.82 9.0 11.3 1.7 8.0 7.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF3584 PF12128.3 EEQ70828.1 - 1 6.6 17.5 1.5 6.0 12.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FUSC PF04632.7 EEQ70828.1 - 1.2 7.4 10.5 1.8 6.8 7.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG6 PF04111.7 EEQ70828.1 - 1.3 8.0 17.0 2.3 7.2 11.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 ADIP PF11559.3 EEQ70828.1 - 1.4 8.8 23.2 2.9 7.7 4.0 3.4 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.7 EEQ70828.1 - 6.6 6.5 7.0 3.1 7.6 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 EEQ70828.1 - 6.6 6.8 11.2 1.4 9.0 4.8 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family GOLGA2L5 PF15070.1 EEQ70828.1 - 6.6 5.0 22.7 16 3.8 15.3 1.7 1 1 1 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 MARVEL PF01284.18 EEQ70829.1 - 9.1e-28 96.8 13.1 1.1e-27 96.5 9.1 1.0 1 0 0 1 1 1 1 Membrane-associating domain F-box PF00646.28 EEQ70829.1 - 0.13 11.9 0.1 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 F-box domain DUF3413 PF11893.3 EEQ70829.1 - 0.44 9.3 9.3 0.55 9.0 6.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3413) Cys_Met_Meta_PP PF01053.15 EEQ70830.1 - 4.1e-150 499.3 0.0 4.6e-150 499.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EEQ70830.1 - 1.1e-13 50.9 0.1 1.9e-13 50.1 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EEQ70830.1 - 1.2e-09 37.5 0.0 1.8e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EEQ70830.1 - 6.2e-08 31.7 0.1 9.4e-08 31.1 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EEQ70830.1 - 0.00015 21.0 0.0 0.00036 19.7 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 EEQ70830.1 - 0.0055 15.4 0.0 0.008 14.9 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 EEQ70830.1 - 0.021 13.1 0.0 0.027 12.7 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase SLA_LP_auto_ag PF05889.8 EEQ70830.1 - 0.027 12.9 0.0 0.036 12.5 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) HCR PF07111.7 EEQ70831.1 - 0.0079 14.2 6.3 0.0088 14.1 4.3 1.0 1 0 0 1 1 1 1 Alpha helical coiled-coil rod protein (HCR) DUF4200 PF13863.1 EEQ70831.1 - 0.027 14.4 0.9 0.037 13.9 0.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) C9orf72-like PF15019.1 EEQ70831.1 - 0.028 13.6 0.3 0.034 13.4 0.2 1.1 1 0 0 1 1 1 0 C9orf72-like protein family TBPIP PF07106.8 EEQ70831.1 - 0.037 13.5 4.0 0.31 10.5 0.6 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 EEQ70831.1 - 0.048 13.6 3.8 4.2 7.4 0.2 2.4 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2205 PF10224.4 EEQ70831.1 - 0.11 12.1 2.0 0.38 10.3 0.3 2.2 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) TMV_coat PF00721.16 EEQ70831.1 - 0.11 12.3 3.8 0.079 12.8 1.8 1.3 1 1 0 1 1 1 0 Virus coat protein (TMV like) Syntaxin PF00804.20 EEQ70831.1 - 0.16 12.1 3.2 0.28 11.3 2.0 1.5 1 1 0 1 1 1 0 Syntaxin HlyD PF00529.15 EEQ70831.1 - 0.17 11.1 6.6 0.21 10.8 4.5 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Syntaxin-6_N PF09177.6 EEQ70831.1 - 0.2 12.0 3.7 0.25 11.7 1.4 1.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal FlxA PF14282.1 EEQ70831.1 - 0.22 11.4 8.9 0.42 10.5 6.2 1.5 1 1 0 1 1 1 0 FlxA-like protein DUF3573 PF12097.3 EEQ70831.1 - 0.26 9.8 3.9 0.36 9.3 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) Muted PF14942.1 EEQ70831.1 - 0.32 10.8 2.2 0.42 10.4 1.5 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF1664 PF07889.7 EEQ70831.1 - 0.35 10.6 2.9 0.38 10.5 1.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) MbeD_MobD PF04899.7 EEQ70831.1 - 0.4 10.6 3.9 0.85 9.5 2.5 1.8 1 1 1 2 2 2 0 MbeD/MobD like DUF972 PF06156.8 EEQ70831.1 - 0.4 11.0 2.3 8.8 6.7 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) MscS_porin PF12795.2 EEQ70831.1 - 0.5 9.6 10.0 0.56 9.4 6.7 1.4 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain SlyX PF04102.7 EEQ70831.1 - 0.6 10.5 3.0 7.4 7.0 0.2 2.3 1 1 1 2 2 2 0 SlyX Reo_sigmaC PF04582.7 EEQ70831.1 - 0.86 8.7 8.0 0.92 8.6 5.5 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Adeno_PIX PF03955.9 EEQ70831.1 - 1.5 9.3 8.3 3.5 8.1 1.4 2.0 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) CENP-F_leu_zip PF10473.4 EEQ70831.1 - 2.2 8.1 7.4 11 5.9 4.6 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DEC-1_N PF04625.8 EEQ70833.1 - 0.28 9.8 3.4 0.33 9.5 2.4 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Rib_recp_KP_reg PF05104.7 EEQ70833.1 - 3 8.3 5.4 3.9 7.9 3.7 1.1 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region PUF PF00806.14 EEQ70837.1 - 2.6e-60 196.6 4.3 7.7e-08 31.4 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DnaB_bind PF10410.4 EEQ70837.1 - 0.022 14.7 0.1 21 5.1 0.0 3.3 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase eIF3_subunit PF08597.5 EEQ70837.1 - 0.029 13.9 0.2 0.05 13.1 0.1 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit IL34 PF15036.1 EEQ70837.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Interleukin 34 DUF3736 PF12540.3 EEQ70838.1 - 0.022 15.0 0.6 0.031 14.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3736) RNA_pol_Rpb2_6 PF00562.23 EEQ70841.1 - 1.1e-117 393.0 0.0 1.9e-117 392.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EEQ70841.1 - 3.4e-54 182.8 1.1 6.4e-54 181.9 0.8 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EEQ70841.1 - 3.3e-29 101.6 4.2 6.5e-29 100.6 2.5 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EEQ70841.1 - 1.3e-28 99.0 0.5 5.7e-27 93.7 0.1 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EEQ70841.1 - 1.7e-22 78.9 0.2 4.2e-22 77.7 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EEQ70841.1 - 1.4e-19 69.6 0.0 2.8e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EEQ70841.1 - 2.1e-13 50.0 1.5 4.7e-13 48.8 1.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Bd3614_N PF14442.1 EEQ70844.1 - 0.6 10.0 2.6 0.95 9.4 1.8 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Glycos_transf_1 PF00534.15 EEQ70845.1 - 2e-18 66.3 0.0 4.3e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EEQ70845.1 - 2.3e-09 37.5 0.1 8.2e-09 35.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EEQ70845.1 - 0.0018 18.4 0.0 0.0035 17.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 E1-E2_ATPase PF00122.15 EEQ70846.1 - 2.5e-61 206.6 7.8 2.5e-61 206.6 5.4 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EEQ70846.1 - 3e-22 80.0 0.0 8.4e-22 78.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEQ70846.1 - 9.2e-13 48.7 0.0 2.2e-12 47.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEQ70846.1 - 2e-11 43.1 0.0 4.7e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EEQ70846.1 - 0.0015 18.1 0.1 0.0029 17.2 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ70846.1 - 0.028 14.3 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Sec3_C PF09763.4 EEQ70847.1 - 0.094 10.8 1.8 0.14 10.2 1.3 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 Pex14_N PF04695.8 EEQ70847.1 - 1.1 9.3 12.6 2.2 8.2 8.7 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4614 PF15391.1 EEQ70847.1 - 3 7.5 19.0 6.5 6.4 13.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) RAP1 PF07218.6 EEQ70847.1 - 5.5 4.9 17.9 7.7 4.4 12.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NTP_transf_5 PF14907.1 EEQ70851.1 - 0.00063 19.1 0.0 0.0008 18.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised nucleotidyltransferase DUF2204 PF09970.4 EEQ70851.1 - 0.025 14.0 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) DUF1814 PF08843.6 EEQ70851.1 - 0.03 14.0 0.0 0.32 10.7 0.0 2.1 1 1 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF1814) RRM_1 PF00076.17 EEQ70853.1 - 2.4e-05 23.8 0.0 4.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ70853.1 - 0.00036 20.3 0.0 0.00072 19.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ70853.1 - 0.00044 20.1 0.0 0.00093 19.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EEQ70853.1 - 0.0026 17.9 0.0 0.0087 16.2 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase II-binding domain. Citrate_synt PF00285.16 EEQ70854.1 - 6.2e-100 334.3 0.0 7.4e-100 334.1 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase XH PF03469.9 EEQ70854.1 - 0.059 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 XH domain Eclosion PF04736.7 EEQ70854.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone Mito_carr PF00153.22 EEQ70856.1 - 2e-27 94.7 5.7 2.2e-11 43.3 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Ank_2 PF12796.2 EEQ70858.1 - 1.1e-24 86.5 0.1 3.9e-13 49.5 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ70858.1 - 1.3e-13 50.0 1.8 0.00019 21.0 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EEQ70858.1 - 5.8e-09 36.2 0.0 8e-06 26.2 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ70858.1 - 1e-08 34.5 0.0 0.11 12.8 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 EEQ70858.1 - 1.6e-07 31.3 0.1 0.00028 21.0 0.2 3.8 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Peptidase_M16 PF00675.15 EEQ70859.1 - 1.9e-21 76.3 0.0 3.6e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EEQ70859.1 - 2e-13 50.4 0.0 5.5e-13 48.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.8 EEQ70860.1 - 5.4e-34 117.8 0.0 5.9e-30 104.6 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EEQ70860.1 - 2.7e-20 72.0 2.0 6.8e-14 51.4 0.0 4.0 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EEQ70860.1 - 1.1e-12 47.3 0.3 6.9e-08 31.9 0.1 2.7 2 0 0 2 2 2 2 TFIIE alpha subunit TrmB PF01978.14 EEQ70860.1 - 0.022 14.4 0.1 2.6 7.8 0.1 3.1 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB PBP1_TM PF14812.1 EEQ70860.1 - 2 8.7 8.4 10 6.5 0.6 3.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal adh_short PF00106.20 EEQ70861.1 - 8.3e-26 90.8 0.7 1.2e-25 90.3 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ70861.1 - 1.5e-10 41.0 0.4 6e-10 39.0 0.2 1.9 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EEQ70861.1 - 8.8e-08 32.2 0.0 1.1e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EEQ70861.1 - 1.9e-06 28.0 0.0 2.8e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EEQ70861.1 - 0.0065 15.7 0.1 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family DUF1776 PF08643.5 EEQ70861.1 - 0.079 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.21 EEQ70861.1 - 0.99 8.9 3.3 0.93 9.0 0.2 2.4 2 1 1 3 3 3 0 Zinc-binding dehydrogenase F-box-like PF12937.2 EEQ70862.1 - 0.0001 21.9 0.3 0.00039 20.0 0.2 2.0 2 0 0 2 2 2 1 F-box-like Ras PF00071.17 EEQ70863.1 - 2e-61 206.1 1.0 2.4e-61 205.8 0.7 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ70863.1 - 4.4e-22 78.7 0.0 6.7e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ70863.1 - 1.3e-14 53.8 0.2 1.7e-14 53.4 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EEQ70863.1 - 1e-07 31.9 0.1 1.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEQ70863.1 - 4.7e-06 26.1 0.3 1.7e-05 24.3 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EEQ70863.1 - 6e-05 22.3 0.1 8e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EEQ70863.1 - 0.0017 17.5 0.3 0.0044 16.2 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEQ70863.1 - 0.0022 18.1 0.1 0.007 16.5 0.0 1.8 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.13 EEQ70863.1 - 0.0046 16.2 0.5 0.053 12.8 0.4 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_15 PF13175.1 EEQ70863.1 - 0.0055 15.7 0.0 0.0075 15.3 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 EEQ70863.1 - 0.011 16.0 0.1 0.018 15.3 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 EEQ70863.1 - 0.011 15.2 0.4 0.045 13.3 0.1 2.1 1 1 1 2 2 2 0 AAA domain SRPRB PF09439.5 EEQ70863.1 - 0.013 14.7 0.1 0.023 13.9 0.1 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EEQ70863.1 - 0.013 14.9 0.0 0.048 13.1 0.0 1.9 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EEQ70863.1 - 0.014 15.2 0.1 0.047 13.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEQ70863.1 - 0.034 14.1 0.3 0.06 13.3 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 EEQ70863.1 - 0.051 13.2 0.2 0.11 12.1 0.0 1.5 1 1 1 2 2 2 0 Archaeal ATPase NTPase_1 PF03266.10 EEQ70863.1 - 0.053 13.2 0.1 0.11 12.2 0.1 1.6 1 1 0 1 1 1 0 NTPase UDG PF03167.14 EEQ70863.1 - 0.069 12.6 0.0 0.091 12.2 0.0 1.2 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily AAA_29 PF13555.1 EEQ70863.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EEQ70863.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Chromo PF00385.19 EEQ70864.1 - 4.7e-09 35.7 0.2 9.1e-09 34.8 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SPT6_acidic PF14632.1 EEQ70864.1 - 0.022 14.9 0.6 0.022 14.9 0.4 2.5 3 0 0 3 3 3 0 Acidic N-terminal SPT6 AAA_2 PF07724.9 EEQ70865.1 - 5e-37 127.4 0.0 6.9e-36 123.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EEQ70865.1 - 3.2e-14 53.2 0.0 6.2e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EEQ70865.1 - 2.1e-08 33.9 0.0 4.5e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EEQ70865.1 - 1.2e-06 28.3 0.0 2.6e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EEQ70865.1 - 0.00016 20.9 0.1 0.0088 15.2 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 EEQ70865.1 - 0.00085 19.4 0.2 0.011 15.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EEQ70865.1 - 0.00091 18.6 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 EEQ70865.1 - 0.0013 19.5 0.2 0.0028 18.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain Sigma54_activat PF00158.21 EEQ70865.1 - 0.0018 17.7 0.0 0.11 11.9 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.1 EEQ70865.1 - 0.0033 17.0 0.0 0.0068 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEQ70865.1 - 0.0043 17.0 2.8 0.0049 16.8 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EEQ70865.1 - 0.0057 15.7 0.2 0.13 11.2 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EEQ70865.1 - 0.031 14.1 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 EEQ70865.1 - 0.045 12.5 0.2 0.11 11.2 0.1 1.5 1 1 0 1 1 1 0 MCM2/3/5 family RNA_helicase PF00910.17 EEQ70865.1 - 0.046 13.8 0.0 0.095 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 EEQ70865.1 - 0.066 12.8 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.15 EEQ70865.1 - 0.071 11.7 0.1 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_25 PF13481.1 EEQ70865.1 - 0.095 12.0 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEQ70865.1 - 0.19 12.0 0.5 0.49 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EEQ70865.1 - 0.51 10.2 0.0 0.51 10.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain SKI PF01202.17 EEQ70865.1 - 0.54 10.1 3.9 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase ORC5_C PF14630.1 EEQ70866.1 - 3.9e-91 305.2 0.0 5.5e-91 304.7 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EEQ70866.1 - 1.4e-12 47.9 0.0 7e-11 42.4 0.0 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEQ70866.1 - 0.001 19.1 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EEQ70866.1 - 0.0014 19.0 0.0 0.0026 18.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EEQ70866.1 - 0.012 15.1 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 EEQ70866.1 - 0.012 15.1 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EEQ70866.1 - 0.021 15.6 0.0 0.041 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EEQ70866.1 - 0.027 14.3 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 EEQ70866.1 - 0.028 13.4 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain ABC_tran PF00005.22 EEQ70866.1 - 0.036 14.3 0.0 0.29 11.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.1 EEQ70866.1 - 0.037 13.9 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EEQ70866.1 - 0.043 12.7 0.0 0.079 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 EEQ70866.1 - 0.052 13.2 0.0 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase Dynamin_N PF00350.18 EEQ70866.1 - 0.067 13.0 0.0 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 Dynamin family DUF815 PF05673.8 EEQ70866.1 - 0.084 11.7 0.0 0.18 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA12 PF10443.4 EEQ70866.1 - 0.12 10.8 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein Guanylate_kin PF00625.16 EEQ70866.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase NACHT PF05729.7 EEQ70866.1 - 0.16 11.6 0.0 3.3 7.3 0.0 2.3 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.18 EEQ70866.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 EEQ70866.1 - 0.19 12.2 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Mak10 PF04112.8 EEQ70868.1 - 5.9e-41 139.4 0.0 1.6e-40 138.0 0.0 1.7 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ATP-synt_Eps PF04627.8 EEQ70869.1 - 4.6e-24 83.7 1.2 4.6e-24 83.7 0.8 1.6 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain CDC45 PF02724.9 EEQ70872.1 - 6.4 4.6 8.3 9.4 4.1 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Kdo PF06293.9 EEQ70873.1 - 0.00011 21.3 0.1 0.0002 20.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ70873.1 - 0.00029 20.6 0.1 0.00081 19.1 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EEQ70873.1 - 0.043 13.1 0.0 0.079 12.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 EEQ70873.1 - 0.079 12.5 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Cpn60_TCP1 PF00118.19 EEQ70874.1 - 1.1e-116 390.4 9.5 1.2e-116 390.2 6.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cofilin_ADF PF00241.15 EEQ70875.1 - 8.6e-20 70.8 0.2 1.1e-19 70.5 0.2 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein COX4 PF02936.9 EEQ70876.1 - 2e-50 170.1 0.2 2.9e-50 169.7 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF2263 PF10021.4 EEQ70878.1 - 3e-32 111.6 0.0 5e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Fapy_DNA_glyco PF01149.19 EEQ70879.1 - 1.7e-27 96.0 0.0 3.2e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 EEQ70879.1 - 4.8e-21 74.3 0.0 8.6e-21 73.4 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 EEQ70879.1 - 0.0084 14.6 0.0 0.047 12.2 0.0 1.9 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Cid2 PF09774.4 EEQ70880.1 - 4.5e-51 172.9 0.0 5.3e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 2-oxoacid_dh PF00198.18 EEQ70881.1 - 1.2e-77 260.3 0.1 1.5e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EEQ70881.1 - 4e-13 48.7 0.0 8.1e-13 47.8 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EEQ70881.1 - 5.4e-13 48.3 2.0 9.6e-13 47.5 0.1 2.2 2 0 0 2 2 2 1 e3 binding domain SKI PF01202.17 EEQ70882.1 - 2e-13 50.5 0.0 2.9e-13 49.9 0.0 1.4 1 1 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 EEQ70882.1 - 3.4e-13 49.6 0.0 8.3e-13 48.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 EEQ70882.1 - 8.7e-13 49.1 0.0 1.2e-12 48.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEQ70882.1 - 2.7e-12 47.1 0.0 4.7e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EEQ70882.1 - 4.4e-07 28.9 0.0 6.7e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein APS_kinase PF01583.15 EEQ70882.1 - 4.8e-06 26.3 0.0 7.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_14 PF13173.1 EEQ70882.1 - 3.5e-05 23.7 0.0 9.2e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEQ70882.1 - 5.4e-05 23.3 0.0 0.0001 22.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EEQ70882.1 - 6.9e-05 23.0 0.1 0.00011 22.4 0.1 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EEQ70882.1 - 8.9e-05 22.5 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain tRNA_lig_kinase PF08303.6 EEQ70882.1 - 0.00031 20.6 0.0 0.00058 19.7 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain NACHT PF05729.7 EEQ70882.1 - 0.00055 19.6 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.7 EEQ70882.1 - 0.00061 18.9 0.0 0.00083 18.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 EEQ70882.1 - 0.00097 19.2 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Cytidylate_kin2 PF13189.1 EEQ70882.1 - 0.0014 18.6 0.1 0.006 16.4 0.1 2.0 1 1 0 1 1 1 1 Cytidylate kinase-like family ABC_tran PF00005.22 EEQ70882.1 - 0.0014 18.9 0.1 0.0033 17.7 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EEQ70882.1 - 0.0015 18.5 0.0 0.0032 17.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.1 EEQ70882.1 - 0.0032 17.0 0.0 0.005 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EEQ70882.1 - 0.0042 16.8 0.0 0.0076 15.9 0.0 1.4 1 0 0 1 1 1 1 NTPase AAA_5 PF07728.9 EEQ70882.1 - 0.0043 16.7 0.0 0.0073 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DNA_pol3_delta2 PF13177.1 EEQ70882.1 - 0.0045 16.6 0.0 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit T2SE PF00437.15 EEQ70882.1 - 0.0052 15.7 0.0 0.0088 14.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 EEQ70882.1 - 0.0054 16.4 0.0 0.014 15.1 0.0 1.7 2 0 0 2 2 1 1 Part of AAA domain RuvB_N PF05496.7 EEQ70882.1 - 0.0064 15.5 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NB-ARC PF00931.17 EEQ70882.1 - 0.0072 15.2 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain ATP_bind_2 PF03668.10 EEQ70882.1 - 0.0089 15.1 0.1 0.5 9.3 0.0 2.3 2 0 0 2 2 2 1 P-loop ATPase protein family ADK PF00406.17 EEQ70882.1 - 0.011 15.5 0.1 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase PRK PF00485.13 EEQ70882.1 - 0.012 15.2 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.1 EEQ70882.1 - 0.012 15.2 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EEQ70882.1 - 0.02 14.5 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase PhoH PF02562.11 EEQ70882.1 - 0.023 13.9 0.0 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein CoaE PF01121.15 EEQ70882.1 - 0.024 14.0 0.0 0.072 12.4 0.0 1.8 1 0 0 1 1 1 0 Dephospho-CoA kinase SRPRB PF09439.5 EEQ70882.1 - 0.03 13.5 0.0 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit KTI12 PF08433.5 EEQ70882.1 - 0.035 13.3 0.1 0.058 12.6 0.1 1.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Viral_helicase1 PF01443.13 EEQ70882.1 - 0.038 13.5 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.16 EEQ70882.1 - 0.041 13.0 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Thymidylate_kin PF02223.12 EEQ70882.1 - 0.043 13.1 0.0 0.73 9.1 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_25 PF13481.1 EEQ70882.1 - 0.045 13.1 0.0 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EEQ70882.1 - 0.048 13.1 0.0 0.11 11.9 0.0 1.5 2 0 0 2 2 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF2075 PF09848.4 EEQ70882.1 - 0.049 12.6 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF258 PF03193.11 EEQ70882.1 - 0.087 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 cobW PF02492.14 EEQ70882.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.12 EEQ70882.1 - 0.13 11.7 0.0 0.34 10.3 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Vps26 PF03643.10 EEQ70885.1 - 8.1e-129 428.2 0.2 9.8e-129 427.9 0.2 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EEQ70885.1 - 0.00028 20.7 0.3 0.6 9.9 0.0 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain DUF432 PF04254.8 EEQ70885.1 - 0.024 14.5 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF432) Sec7_N PF12783.2 EEQ70886.1 - 8.4e-42 142.4 0.7 8.4e-42 142.4 0.5 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EEQ70886.1 - 0.0035 16.8 3.0 0.016 14.6 0.0 3.8 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) DUF3926 PF13080.1 EEQ70886.1 - 0.029 13.8 0.6 0.069 12.6 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) UQ_con PF00179.21 EEQ70887.1 - 1.1e-14 54.0 0.0 1.2e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EEQ70887.1 - 0.0032 17.3 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 RWD domain Complex1_LYR_1 PF13232.1 EEQ70888.1 - 1.2e-11 44.6 0.0 1.2e-11 44.6 0.0 1.9 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 EEQ70888.1 - 1.4e-10 40.8 1.0 4.1e-10 39.3 0.0 2.3 3 0 0 3 3 3 1 Complex 1 protein (LYR family) UNC119_bdg PF15435.1 EEQ70888.1 - 0.024 13.9 0.1 0.042 13.1 0.0 1.4 1 0 0 1 1 1 0 UNC119-binding protein C5orf30 homologue RWD PF05773.17 EEQ70889.1 - 4.3e-25 87.8 0.1 8.2e-25 86.8 0.1 1.5 1 0 0 1 1 1 1 RWD domain DUF1485 PF07364.7 EEQ70889.1 - 0.0026 16.9 0.1 0.0038 16.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1485) RNase_H2-Ydr279 PF09468.5 EEQ70889.1 - 0.072 12.2 4.3 0.099 11.8 3.0 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DHHA2 PF02833.9 EEQ70889.1 - 0.11 12.7 2.7 0.17 12.0 1.3 1.7 1 1 1 2 2 2 0 DHHA2 domain DDHD PF02862.12 EEQ70889.1 - 0.14 11.9 0.8 0.19 11.5 0.6 1.1 1 0 0 1 1 1 0 DDHD domain TPR_12 PF13424.1 EEQ70890.1 - 9.3e-14 51.1 0.1 8.4e-07 28.8 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ70890.1 - 1.4e-12 47.0 0.0 5.7e-07 29.1 0.0 3.5 2 1 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EEQ70890.1 - 7.6e-11 41.0 0.2 5e-05 22.9 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ70890.1 - 1.7e-10 41.0 2.0 0.00018 21.7 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ70890.1 - 1.8e-09 37.9 2.3 0.00026 21.5 0.0 4.3 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ70890.1 - 2.8e-09 36.1 0.0 5.1e-05 22.6 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ70890.1 - 1.6e-08 34.2 4.4 0.26 11.1 0.2 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ70890.1 - 8.6e-08 32.1 6.0 0.08 13.6 0.0 5.3 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ70890.1 - 4.1e-07 29.3 0.0 2.8e-05 23.5 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EEQ70890.1 - 1.7e-05 24.5 4.7 0.63 10.0 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EEQ70890.1 - 4.9e-05 23.3 0.0 0.027 14.5 0.0 3.5 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EEQ70890.1 - 0.00032 20.2 0.2 0.032 14.0 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 EEQ70890.1 - 0.00051 19.1 0.5 0.13 11.3 0.0 3.7 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ70890.1 - 0.0027 17.7 0.0 42 4.7 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 EEQ70890.1 - 0.0064 16.8 7.2 0.59 10.7 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat DBC1 PF14443.1 EEQ70890.1 - 0.015 14.8 5.8 0.31 10.5 0.0 2.4 2 0 0 2 2 2 0 DBC1 TPR_6 PF13174.1 EEQ70890.1 - 0.04 14.3 2.6 2.1 8.9 0.0 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_21 PF09976.4 EEQ70890.1 - 0.14 12.0 3.6 0.22 11.4 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat SIR2 PF02146.12 EEQ70891.1 - 2.7e-60 203.1 0.0 3.9e-60 202.6 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EEQ70891.1 - 7.4e-05 22.3 0.1 0.00013 21.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EEQ70891.1 - 0.0012 18.6 0.1 0.36 10.6 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Ribosomal_L34e PF01199.13 EEQ70891.1 - 0.15 12.3 1.0 0.27 11.4 0.7 1.3 1 0 0 1 1 1 0 Ribosomal protein L34e Imm7 PF15588.1 EEQ70892.1 - 0.021 14.8 0.0 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 7 Glyco_transf_34 PF05637.7 EEQ70893.1 - 9.7e-16 57.9 0.0 2.2e-12 46.9 0.0 2.1 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EEQ70893.1 - 8.7e-05 21.9 0.0 0.00011 21.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF273 DUF2985 PF11204.3 EEQ70894.1 - 6.5e-29 99.5 4.2 1.3e-28 98.5 2.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) IcmL PF11393.3 EEQ70895.1 - 0.093 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Macrophage killing protein with similarity to conjugation protein Latrotoxin_C PF15658.1 EEQ70897.1 - 0.00032 20.5 0.0 0.002 17.9 0.0 2.0 2 0 0 2 2 2 1 Latrotoxin C-terminal domain HSP70 PF00012.15 EEQ70897.1 - 0.011 13.6 0.1 0.11 10.3 0.0 2.1 2 0 0 2 2 2 0 Hsp70 protein MreB_Mbl PF06723.8 EEQ70897.1 - 0.02 13.4 0.2 0.084 11.4 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein ClpB_D2-small PF10431.4 EEQ70898.1 - 0.16 11.9 0.1 3.3 7.6 0.0 2.2 1 1 1 2 2 2 0 C-terminal, D2-small domain, of ClpB protein UPF0020 PF01170.13 EEQ70899.1 - 1.6e-10 40.8 0.0 2.7e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EEQ70899.1 - 3.5e-07 30.2 0.0 6.9e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 EEQ70899.1 - 0.0052 16.3 0.0 0.081 12.4 0.0 2.3 2 0 0 2 2 2 1 DNA methylase N6_Mtase PF02384.11 EEQ70899.1 - 0.0089 15.1 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase MethyltransfD12 PF02086.10 EEQ70899.1 - 0.063 12.7 0.0 0.063 12.7 0.0 2.2 4 0 0 4 4 4 0 D12 class N6 adenine-specific DNA methyltransferase HIT PF01230.18 EEQ70900.1 - 6.7e-16 58.6 0.0 2.1e-15 57.0 0.0 1.8 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EEQ70900.1 - 0.00038 20.6 0.0 0.00084 19.5 0.0 1.5 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EEQ70900.1 - 0.0029 17.2 0.0 0.02 14.5 0.0 2.0 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 Cyclin_N PF00134.18 EEQ70901.1 - 4.2e-46 155.6 0.1 1.3e-44 150.8 0.1 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EEQ70901.1 - 3.5e-35 120.4 0.1 6.9e-35 119.5 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ribosomal_L2_C PF03947.13 EEQ70902.1 - 5.1e-48 162.1 0.5 2.9e-34 117.6 0.4 2.6 2 0 0 2 2 2 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EEQ70902.1 - 5.9e-29 99.8 0.8 1e-28 99.0 0.6 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Fungal_trans PF04082.13 EEQ70904.1 - 7.3e-23 80.7 0.3 1.3e-22 79.9 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ70904.1 - 1.3e-09 37.7 9.7 2.3e-09 36.9 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 EEQ70905.1 - 1.1e-32 110.6 16.2 6.9e-09 35.2 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EEQ70905.1 - 2.5e-10 39.2 0.0 2.2e-08 32.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 EEQ70905.1 - 5.6e-05 22.9 0.2 0.18 11.4 0.0 2.8 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EEQ70905.1 - 0.0014 16.9 0.2 0.049 11.7 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 IKI3 PF04762.7 EEQ70905.1 - 0.018 12.8 0.0 0.049 11.4 0.0 1.6 2 0 0 2 2 2 0 IKI3 family Apc4_WD40 PF12894.2 EEQ70905.1 - 0.12 11.9 0.0 0.34 10.4 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.5 EEQ70905.1 - 0.24 9.5 0.2 0.35 9.0 0.1 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Coatomer_WDAD PF04053.9 EEQ70905.1 - 0.25 10.0 0.0 1 8.0 0.0 1.9 2 0 0 2 2 2 0 Coatomer WD associated region Ribonuc_P_40 PF08584.6 EEQ70906.1 - 6.4e-82 274.7 0.0 8e-82 274.4 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Dna2 PF08696.6 EEQ70907.1 - 2.2e-74 249.2 0.2 4e-74 248.4 0.1 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 EEQ70907.1 - 9.1e-52 175.3 0.0 1.6e-51 174.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEQ70907.1 - 4.5e-42 144.2 0.2 2.6e-39 135.1 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EEQ70907.1 - 2.1e-12 47.0 0.0 4.3e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.12 EEQ70907.1 - 2.4e-12 47.0 0.3 1.5e-09 37.9 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.2 EEQ70907.1 - 2.2e-11 43.6 0.1 4.8e-11 42.5 0.1 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_19 PF13245.1 EEQ70907.1 - 3.1e-11 42.8 0.2 7.4e-11 41.6 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain DUF911 PF06023.7 EEQ70907.1 - 1.5e-07 30.9 0.0 3.1e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF911) Viral_helicase1 PF01443.13 EEQ70907.1 - 3.6e-07 29.9 0.3 0.22 11.0 0.1 3.5 2 1 1 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 EEQ70907.1 - 3.1e-05 23.6 0.1 0.00013 21.6 0.0 2.0 2 0 0 2 2 2 1 Helicase UvrD-helicase PF00580.16 EEQ70907.1 - 0.00026 20.4 0.2 0.00047 19.5 0.1 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 EEQ70907.1 - 0.00066 18.7 0.0 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase SRP54 PF00448.17 EEQ70907.1 - 0.0011 18.4 0.1 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain CbiA PF01656.18 EEQ70907.1 - 0.0014 18.0 0.0 0.0032 16.9 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EEQ70907.1 - 0.0018 17.9 0.1 0.0038 16.9 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EEQ70907.1 - 0.0069 16.3 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EEQ70907.1 - 0.007 15.7 0.0 0.02 14.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EEQ70907.1 - 0.0082 15.9 0.4 0.03 14.1 0.2 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EEQ70907.1 - 0.012 14.6 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 EEQ70907.1 - 0.024 14.1 0.1 0.09 12.2 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 EEQ70907.1 - 0.038 13.8 0.2 0.095 12.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_10 PF12846.2 EEQ70907.1 - 0.042 13.2 0.1 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 EEQ70907.1 - 0.042 14.1 0.1 0.33 11.2 0.0 2.6 3 0 0 3 3 1 0 ABC transporter DUF853 PF05872.7 EEQ70907.1 - 0.046 12.0 0.1 0.075 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_22 PF13401.1 EEQ70907.1 - 0.06 13.4 0.6 0.39 10.8 0.1 2.7 3 1 0 3 3 1 0 AAA domain ArgK PF03308.11 EEQ70907.1 - 0.072 11.8 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 ArgK protein PhoH PF02562.11 EEQ70907.1 - 0.12 11.6 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.17 EEQ70907.1 - 0.13 11.0 0.2 1.6 7.4 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.24 EEQ70907.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EEQ70907.1 - 0.17 11.5 0.1 0.43 10.2 0.1 1.6 1 0 0 1 1 1 0 NTPase Arch_ATPase PF01637.13 EEQ70907.1 - 0.21 11.2 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase Mito_carr PF00153.22 EEQ70908.1 - 3.5e-71 234.9 1.0 4.6e-26 90.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HLH PF00010.21 EEQ70912.1 - 2.1e-12 46.5 0.0 5.7e-12 45.1 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain P53_C PF11619.3 EEQ70913.1 - 0.079 12.7 0.3 2.3 8.0 0.0 2.1 2 0 0 2 2 2 0 Transcription factor P53 - C terminal domain Got1 PF04178.7 EEQ70914.1 - 2.8e-31 108.0 15.7 2.8e-31 108.0 10.9 1.7 2 0 0 2 2 2 1 Got1/Sft2-like family Claudin_2 PF13903.1 EEQ70914.1 - 1.7 8.3 9.9 1.3e+02 2.1 6.9 2.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction tRNA_lig_CPD PF08302.6 EEQ70915.1 - 5.8e-86 287.8 0.0 8.3e-86 287.3 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.5 EEQ70915.1 - 4.8e-82 274.7 0.0 1e-81 273.6 0.0 1.6 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 EEQ70915.1 - 8.3e-53 178.6 1.1 1.5e-52 177.8 0.7 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_33 PF13671.1 EEQ70915.1 - 0.0016 18.3 0.1 0.0038 17.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEQ70915.1 - 0.02 15.7 0.0 0.087 13.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EEQ70915.1 - 0.078 13.2 0.5 0.39 11.0 0.3 2.2 1 1 0 1 1 1 0 ABC transporter Ank_5 PF13857.1 EEQ70916.1 - 2.8e-10 40.0 0.2 1.2e-09 38.1 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEQ70916.1 - 3.9e-07 30.4 0.0 8.7e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EEQ70916.1 - 2.7e-05 23.7 0.5 0.00071 19.2 0.1 2.8 2 1 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 EEQ70916.1 - 8.6e-05 22.7 0.1 0.00018 21.7 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EEQ70916.1 - 0.00017 21.4 0.2 0.0012 18.9 0.1 2.4 2 1 0 2 2 2 1 Ankyrin repeat YejG PF13989.1 EEQ70916.1 - 0.0005 20.0 0.0 0.00087 19.3 0.0 1.3 1 0 0 1 1 1 1 YejG-like protein Mod_r PF07200.8 EEQ70917.1 - 3.5e-11 43.2 2.1 4.7e-11 42.8 1.5 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein ATG16 PF08614.6 EEQ70917.1 - 0.022 14.5 1.8 0.022 14.5 1.3 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) PAP2 PF01569.16 EEQ70918.1 - 3.1e-21 75.4 1.0 1.1e-20 73.6 0.7 1.9 1 1 0 1 1 1 1 PAP2 superfamily Shisa PF13908.1 EEQ70918.1 - 0.29 11.2 1.8 5.7 7.0 0.5 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator AIG2 PF06094.7 EEQ70919.1 - 6.3e-09 36.2 0.0 7.8e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 AIG2-like family Aldo_ket_red PF00248.16 EEQ70920.1 - 1.3e-53 181.7 0.1 1.5e-53 181.5 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GFA PF04828.9 EEQ70923.1 - 1.3e-11 44.2 0.2 2.1e-11 43.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Pet191_N PF10203.4 EEQ70924.1 - 0.016 15.2 0.2 0.024 14.6 0.2 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 EEQ70924.1 - 0.038 13.9 0.2 0.059 13.3 0.1 1.4 1 0 0 1 1 1 0 CHCH domain NPR3 PF03666.8 EEQ70925.1 - 4.4e-129 430.9 1.5 1.7e-81 274.1 0.0 3.7 3 1 1 4 4 4 3 Nitrogen Permease regulator of amino acid transport activity 3 AMP-binding PF00501.23 EEQ70926.1 - 2.9e-49 167.5 0.0 4.2e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 EEQ70926.1 - 1.3e-29 104.0 0.8 2.3e-29 103.2 0.1 1.8 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 EEQ70926.1 - 0.00056 20.1 0.2 0.0012 19.0 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site VirJ PF06057.6 EEQ70926.1 - 0.034 13.9 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_5 PF12695.2 EEQ70926.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family PROL5-SMR PF15621.1 EEQ70932.1 - 0.13 12.6 0.1 0.32 11.4 0.1 1.6 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family La PF05383.12 EEQ70933.1 - 1.8e-17 62.8 0.3 2.8e-17 62.2 0.2 1.3 1 0 0 1 1 1 1 La domain Band_7 PF01145.20 EEQ70934.1 - 1.2e-30 106.7 0.7 2.1e-30 105.9 0.5 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EEQ70934.1 - 0.068 12.6 0.0 0.14 11.6 0.0 1.5 1 1 0 1 1 1 0 SPFH domain-Band 7 family DRTGG PF07085.7 EEQ70934.1 - 0.15 11.7 1.4 0.85 9.2 0.0 2.4 2 0 0 2 2 2 0 DRTGG domain Hira PF07569.6 EEQ70935.1 - 8.2e-83 276.9 0.0 1.4e-82 276.1 0.0 1.4 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 EEQ70935.1 - 4e-40 134.2 23.1 4e-07 29.6 0.0 8.9 8 0 0 8 8 8 7 WD domain, G-beta repeat HIRA_B PF09453.5 EEQ70935.1 - 2.8e-10 39.4 0.2 7.5e-10 38.0 0.1 1.8 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 EEQ70935.1 - 4.4e-06 26.2 2.6 4.8 6.9 0.0 5.5 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EEQ70935.1 - 0.003 15.4 0.0 0.011 13.5 0.0 1.9 2 0 0 2 2 2 1 IKI3 family Lactamase_B PF00753.22 EEQ70936.1 - 0.003 17.2 0.3 0.0032 17.1 0.2 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily YchF-GTPase_C PF06071.8 EEQ70937.1 - 2e-33 114.0 0.3 4.7e-33 112.8 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EEQ70937.1 - 6.8e-13 48.6 0.0 1.2e-12 47.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEQ70937.1 - 0.0018 17.5 0.0 0.0032 16.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 EEQ70937.1 - 0.011 15.5 0.2 0.038 13.8 0.1 1.9 1 1 0 1 1 1 0 TGS domain PPAK PF02818.10 EEQ70937.1 - 0.028 14.3 5.7 0.086 12.7 3.9 1.9 1 0 0 1 1 1 0 PPAK motif MobB PF03205.9 EEQ70937.1 - 0.061 13.0 0.6 2.7 7.6 0.0 2.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B SecA_PP_bind PF01043.15 EEQ70937.1 - 0.15 12.4 0.1 0.37 11.1 0.1 1.6 1 0 0 1 1 1 0 SecA preprotein cross-linking domain AAA_23 PF13476.1 EEQ70937.1 - 0.23 11.7 1.9 1.1 9.5 1.3 2.0 1 1 0 1 1 1 0 AAA domain PUA PF01472.15 EEQ70938.1 - 2e-13 49.8 0.1 4e-13 48.9 0.1 1.5 1 1 0 1 1 1 1 PUA domain RIC1 PF07064.8 EEQ70939.1 - 1e-90 303.7 0.1 1.3e-90 303.3 0.0 1.2 1 0 0 1 1 1 1 RIC1 TPR_11 PF13414.1 EEQ70940.1 - 7.3e-22 76.7 7.5 1.4e-17 63.0 0.7 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EEQ70940.1 - 8.6e-14 50.2 3.2 0.004 16.9 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ70940.1 - 1.1e-13 50.0 2.6 0.00097 18.6 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ70940.1 - 8.2e-12 45.4 12.2 2.9e-07 30.9 0.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ70940.1 - 5.6e-08 32.0 0.1 0.22 11.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ70940.1 - 5.1e-07 29.3 1.8 0.0021 18.0 0.3 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ70940.1 - 1.2e-06 28.6 2.6 0.018 15.6 0.2 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ70940.1 - 8.1e-06 25.6 1.8 0.016 15.1 0.8 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ70940.1 - 3.6e-05 23.9 0.3 0.0014 18.9 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ70940.1 - 4e-05 23.3 0.5 0.0038 17.0 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ70940.1 - 6.9e-05 22.3 1.8 1.1 9.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat XPC-binding PF09280.6 EEQ70940.1 - 0.024 14.0 1.7 0.024 14.0 1.2 1.7 2 0 0 2 2 2 0 XPC-binding domain BTAD PF03704.12 EEQ70940.1 - 0.04 14.2 0.2 0.64 10.3 0.1 2.2 2 0 0 2 2 2 0 Bacterial transcriptional activator domain MIT PF04212.13 EEQ70940.1 - 0.05 13.4 2.8 7 6.6 0.0 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 EEQ70940.1 - 0.62 10.6 6.9 3.6 8.2 0.2 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Tim44 PF04280.10 EEQ70941.1 - 8.5e-33 113.4 0.1 1.8e-32 112.3 0.0 1.6 2 0 0 2 2 2 1 Tim44-like domain Ribosomal_S11 PF00411.14 EEQ70942.1 - 8e-10 38.8 0.0 2e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S11 Ank_5 PF13857.1 EEQ70943.1 - 5.3e-17 61.4 0.0 8.3e-12 44.9 0.0 5.3 5 0 0 5 5 5 1 Ankyrin repeats (many copies) VPS9 PF02204.13 EEQ70943.1 - 2.5e-16 59.6 0.0 5.4e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.2 EEQ70943.1 - 7.6e-11 42.2 0.0 6e-06 26.5 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EEQ70943.1 - 2.2e-07 30.4 0.0 1.9 8.9 0.0 6.3 6 0 0 6 6 6 1 Ankyrin repeat PX PF00787.19 EEQ70943.1 - 1e-06 28.5 0.2 2.8e-06 27.0 0.1 1.8 1 0 0 1 1 1 1 PX domain Ank_4 PF13637.1 EEQ70943.1 - 4.6e-06 26.9 0.4 0.082 13.4 0.0 4.9 3 2 2 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.25 EEQ70943.1 - 1.3e-05 24.7 0.2 0.073 12.9 0.0 5.1 5 1 0 5 5 5 1 Ankyrin repeat Inhibitor_I78 PF11720.3 EEQ70945.1 - 4.1e-14 52.0 0.0 4.9e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EEQ70945.1 - 0.0004 20.4 0.2 0.0006 19.9 0.2 1.4 1 1 0 1 1 1 1 Potato inhibitor I family Nefa_Nip30_N PF10187.4 EEQ70947.1 - 4.3e-34 116.7 12.8 4.3e-34 116.7 8.9 1.8 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2075 PF09848.4 EEQ70947.1 - 0.0046 15.9 1.3 0.0053 15.7 0.9 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) CK_II_beta PF01214.13 EEQ70949.1 - 4.3e-74 247.9 0.1 5.3e-74 247.7 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit MTBP_C PF14920.1 EEQ70950.1 - 0.24 10.8 1.1 0.3 10.5 0.7 1.1 1 0 0 1 1 1 0 MDM2-binding BBE PF08031.7 EEQ70951.1 - 9.3e-06 25.4 0.1 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 EEQ70951.1 - 0.0074 15.7 0.3 0.014 14.8 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Dabb PF07876.7 EEQ70952.1 - 3.6e-17 62.6 0.0 4.5e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Fungal_trans_2 PF11951.3 EEQ70953.1 - 4e-25 88.2 0.3 6.1e-25 87.6 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ70953.1 - 2.1e-07 30.7 11.3 4.8e-07 29.5 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAD PF03068.10 EEQ70954.1 - 9.5e-26 90.1 0.0 1.2e-22 79.9 0.0 2.8 1 1 0 2 2 2 2 Protein-arginine deiminase (PAD) Abhydrolase_5 PF12695.2 EEQ70955.1 - 0.00022 20.9 0.1 0.00035 20.3 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EEQ70955.1 - 0.0011 18.6 0.2 0.014 14.9 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEQ70955.1 - 0.0025 17.7 0.1 0.0036 17.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 EEQ70955.1 - 0.011 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF2974 PF11187.3 EEQ70955.1 - 0.024 14.0 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.15 EEQ70955.1 - 0.035 13.6 0.0 0.074 12.5 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.15 EEQ70955.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain JAB PF01398.16 EEQ70956.1 - 7.4e-07 28.9 0.3 6.2e-06 25.9 0.2 2.2 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Phage_XkdX PF09693.5 EEQ70956.1 - 0.12 11.8 0.7 0.35 10.4 0.2 1.9 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) GDE_N PF12439.3 EEQ70956.1 - 0.15 11.3 4.1 0.19 10.9 0.5 2.2 2 1 0 2 2 2 0 Glycogen debranching enzyme N terminal HMG_box PF00505.14 EEQ70959.1 - 9.2e-11 41.8 6.4 9.2e-11 41.8 4.4 3.8 3 1 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EEQ70959.1 - 6.7e-08 32.7 6.1 6.7e-08 32.7 4.2 4.0 4 1 0 4 4 4 1 HMG-box domain DUF1363 PF07101.6 EEQ70959.1 - 0.048 13.7 0.6 0.087 12.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1363) Presenilin PF01080.12 EEQ70959.1 - 0.18 10.6 3.4 0.3 9.8 2.3 1.3 1 0 0 1 1 1 0 Presenilin DUF3069 PF11269.3 EEQ70959.1 - 0.19 11.8 0.1 0.19 11.8 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3069) Podoplanin PF05808.6 EEQ70959.1 - 0.43 10.1 4.8 0.69 9.4 3.3 1.3 1 0 0 1 1 1 0 Podoplanin RR_TM4-6 PF06459.7 EEQ70959.1 - 3.9 7.3 11.8 21 4.8 0.0 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DEAD PF00270.24 EEQ70960.1 - 1.2e-45 155.0 0.0 2.7e-45 153.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ70960.1 - 1.2e-24 85.9 0.0 2.9e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EEQ70960.1 - 0.00069 18.4 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C2H2 PF00096.21 EEQ70962.1 - 0.0035 17.5 2.9 5.4 7.5 0.0 3.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type DUF3106 PF11304.3 EEQ70963.1 - 0.039 14.3 0.7 0.083 13.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) DUF1180 PF06679.7 EEQ70963.1 - 0.14 12.0 0.7 0.19 11.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) AMP-binding PF00501.23 EEQ70964.1 - 1.5e-32 112.5 0.1 2e-20 72.6 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ70964.1 - 1.6e-06 28.9 0.1 3.6e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-C2H2_4 PF13894.1 EEQ70966.1 - 1.8e-06 27.8 13.8 6.1e-05 23.0 1.6 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ70966.1 - 2.6e-06 27.4 12.5 5.3e-05 23.3 2.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEQ70966.1 - 1.9e-05 24.6 1.9 1.9e-05 24.6 1.3 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 EEQ70966.1 - 0.00076 19.6 8.2 0.0022 18.1 0.4 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EEQ70966.1 - 0.034 14.3 1.2 0.034 14.3 0.8 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EEQ70966.1 - 0.057 13.5 4.2 0.1 12.7 2.9 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF2225 PF09986.4 EEQ70966.1 - 0.1 12.0 0.1 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_6 PF13912.1 EEQ70966.1 - 0.16 11.9 1.4 0.37 10.7 1.0 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger BROMI PF14961.1 EEQ70968.1 - 0.046 10.8 1.1 0.057 10.5 0.8 1.1 1 0 0 1 1 1 0 Broad-minded protein DUF2116 PF09889.4 EEQ70968.1 - 5.6 6.8 6.7 2.4 8.0 0.2 2.7 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Kelch_6 PF13964.1 EEQ70971.1 - 9.6e-07 28.7 1.4 0.014 15.4 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 EEQ70971.1 - 0.0054 16.6 4.2 0.26 11.3 0.1 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 EEQ70971.1 - 0.056 12.9 4.3 0.92 9.1 0.0 3.4 3 0 0 3 3 3 0 Kelch motif HAT PF02184.11 EEQ70972.1 - 2.1e-23 81.7 77.7 1.5e-13 50.2 4.0 13.3 14 0 0 14 14 14 7 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 EEQ70972.1 - 6.8e-19 66.6 18.4 0.00042 20.7 0.1 11.6 7 3 7 14 14 13 3 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ70972.1 - 8.8e-18 64.4 0.1 2.8e-05 24.3 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ70972.1 - 2.6e-17 62.9 4.5 0.024 15.2 0.0 7.4 8 0 0 8 8 7 3 Tetratricopeptide repeat Suf PF05843.9 EEQ70972.1 - 5.2e-16 59.2 23.1 0.0014 18.4 0.2 7.2 2 1 5 7 7 7 5 Suppressor of forked protein (Suf) TPR_2 PF07719.12 EEQ70972.1 - 2.4e-07 30.1 13.5 0.019 14.8 0.0 7.8 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ70972.1 - 1.6e-06 27.5 3.9 4.6 7.2 0.0 6.6 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ70972.1 - 4.7e-06 26.1 2.9 0.5 10.0 0.0 5.6 6 1 0 6 6 6 2 TPR repeat U3_assoc_6 PF08640.6 EEQ70972.1 - 1.6e-05 24.5 23.0 0.014 15.1 1.5 7.1 5 2 2 7 7 7 2 U3 small nucleolar RNA-associated protein 6 TPR_17 PF13431.1 EEQ70972.1 - 6.6e-05 22.8 1.3 9.7 6.6 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ70972.1 - 0.00043 20.1 15.5 2.8 7.9 0.0 7.8 7 2 1 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ70972.1 - 0.0013 18.2 1.1 5.7 6.7 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EEQ70972.1 - 0.0099 14.7 32.0 0.026 13.4 3.9 6.6 3 3 3 7 7 7 2 NRDE-2, necessary for RNA interference TPR_7 PF13176.1 EEQ70972.1 - 0.033 13.9 12.7 4.4 7.3 0.0 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ70972.1 - 0.14 12.6 20.3 10 6.8 0.0 7.6 9 0 0 9 9 9 0 Tetratricopeptide repeat Prp31_C PF09785.4 EEQ70973.1 - 7.4e-45 152.3 0.9 1.4e-44 151.5 0.6 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 EEQ70973.1 - 8.6e-40 135.4 0.0 1.5e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EEQ70973.1 - 9.8e-21 73.3 0.1 2e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain Vint PF14623.1 EEQ70975.1 - 9.1e-52 174.8 0.0 1.5e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.1 EEQ70975.1 - 1e-31 108.8 0.0 2.4e-31 107.6 0.0 1.7 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_2 PF13519.1 EEQ70975.1 - 1.4e-17 64.3 0.0 3.8e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EEQ70975.1 - 2.4e-14 53.3 0.0 2.9e-13 49.8 0.0 2.6 1 1 1 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 EEQ70975.1 - 3.7e-14 52.8 0.0 5.1e-13 49.1 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain Hint_2 PF13403.1 EEQ70975.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Hint domain Beta-lactamase PF00144.19 EEQ70978.1 - 3.8e-43 147.7 0.0 5.4e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase MFS_1 PF07690.11 EEQ70979.1 - 1.7e-49 168.4 27.1 5.1e-43 147.1 9.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EEQ70979.1 - 0.00038 18.7 4.5 0.00038 18.7 3.1 2.3 2 1 0 2 2 2 1 Transmembrane secretion effector OATP PF03137.15 EEQ70979.1 - 0.15 10.0 0.0 0.15 10.0 0.0 2.7 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF2371 PF10177.4 EEQ70979.1 - 0.9 9.4 4.7 2.9 7.7 1.3 3.1 3 1 0 3 3 3 0 Uncharacterised conserved protein (DUF2371) DUF2721 PF11026.3 EEQ70979.1 - 1.3 8.6 10.7 6.6 6.3 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2721) AdoHcyase PF05221.12 EEQ70980.1 - 2e-133 443.4 0.1 2.3e-133 443.2 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EEQ70980.1 - 7e-85 282.8 2.0 1.3e-84 281.9 1.4 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EEQ70980.1 - 7.9e-08 31.6 0.1 1.7e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EEQ70980.1 - 0.00063 19.3 0.1 0.0011 18.6 0.1 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.7 EEQ70980.1 - 0.00093 18.6 0.1 0.0017 17.7 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EEQ70980.1 - 0.0053 16.7 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 EEQ70980.1 - 0.039 13.8 0.9 6.9 6.5 0.0 2.5 2 0 0 2 2 2 0 short chain dehydrogenase UPF0261 PF06792.6 EEQ70981.1 - 4.1e-148 493.1 0.1 4.7e-148 492.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) TIM-br_sig_trns PF09370.5 EEQ70982.1 - 1.8e-135 450.1 0.1 2.1e-135 449.9 0.1 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 EEQ70982.1 - 0.0012 18.0 0.2 0.002 17.3 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase PcrB PF01884.12 EEQ70982.1 - 0.02 14.1 0.7 2.6 7.2 0.0 2.7 2 1 0 3 3 3 0 PcrB family Cecropin PF00272.14 EEQ70982.1 - 0.049 13.1 0.3 0.13 11.8 0.2 1.7 1 0 0 1 1 1 0 Cecropin family Radical_SAM PF04055.16 EEQ70982.1 - 0.078 13.1 0.0 0.29 11.3 0.0 1.7 1 1 1 2 2 2 0 Radical SAM superfamily zf-H2C2_2 PF13465.1 EEQ70985.1 - 1.7e-08 34.3 9.3 5.9e-07 29.4 0.7 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EEQ70985.1 - 1.5e-05 25.0 0.7 1.5e-05 25.0 0.5 3.6 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ70985.1 - 6.4e-05 23.0 8.5 0.00012 22.1 0.3 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEQ70985.1 - 0.055 13.6 1.7 0.29 11.3 0.2 2.9 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EEQ70985.1 - 0.067 13.1 0.3 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger SNF2_N PF00176.18 EEQ70986.1 - 2.3e-66 223.6 0.0 3.9e-66 222.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EEQ70986.1 - 2.6e-21 75.0 2.8 4e-12 45.6 0.7 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EEQ70986.1 - 3.1e-12 46.1 0.0 8.8e-12 44.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.1 EEQ70986.1 - 9.1e-10 38.6 1.7 3.1e-09 36.9 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) ResIII PF04851.10 EEQ70986.1 - 4.3e-06 26.6 0.0 0.00048 20.0 0.0 3.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit ABC_tran PF00005.22 EEQ70987.1 - 5.3e-35 120.6 0.0 1e-17 64.6 0.0 2.7 3 0 0 3 3 2 2 ABC transporter RLI PF04068.10 EEQ70987.1 - 1.1e-14 53.7 5.9 1.1e-14 53.7 4.1 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 EEQ70987.1 - 2.4e-14 53.9 4.9 0.0021 18.0 0.0 4.4 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 EEQ70987.1 - 4.2e-11 42.4 1.3 0.0031 16.7 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EEQ70987.1 - 1.1e-05 24.6 0.1 1.6 7.7 0.0 4.2 5 0 0 5 5 5 2 AAA ATPase domain AAA_17 PF13207.1 EEQ70987.1 - 1.2e-05 26.1 1.1 0.12 13.1 0.1 3.3 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 EEQ70987.1 - 3.6e-05 23.9 0.0 0.042 14.0 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EEQ70987.1 - 4.7e-05 23.7 0.0 0.54 10.5 0.0 3.1 2 0 0 2 2 2 2 AAA domain Fer4 PF00037.22 EEQ70987.1 - 7.7e-05 22.1 2.5 7.7e-05 22.1 1.7 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_22 PF13401.1 EEQ70987.1 - 7.8e-05 22.8 0.0 0.029 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EEQ70987.1 - 8.8e-05 21.9 0.2 0.073 12.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Rad17 PF03215.10 EEQ70987.1 - 0.00015 20.5 0.0 0.067 11.8 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein DUF258 PF03193.11 EEQ70987.1 - 0.00032 19.9 2.1 0.71 9.0 0.0 3.1 3 0 0 3 3 2 2 Protein of unknown function, DUF258 VirE PF05272.6 EEQ70987.1 - 0.00048 19.6 0.1 0.95 8.9 0.0 2.4 2 0 0 2 2 2 2 Virulence-associated protein E AAA_25 PF13481.1 EEQ70987.1 - 0.0014 18.0 0.0 1 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EEQ70987.1 - 0.0021 18.5 0.1 0.15 12.5 0.0 2.8 3 0 0 3 3 2 1 Miro-like protein Fer4_21 PF14697.1 EEQ70987.1 - 0.0023 17.7 11.3 0.0044 16.8 7.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain RNA_helicase PF00910.17 EEQ70987.1 - 0.0026 17.9 0.1 1.2 9.3 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 EEQ70987.1 - 0.0044 16.9 0.0 0.31 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEQ70987.1 - 0.0045 17.0 0.0 1.1 9.2 0.0 2.5 3 0 0 3 3 2 1 AAA ATPase domain MobB PF03205.9 EEQ70987.1 - 0.0045 16.6 1.0 0.68 9.6 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_6 PF12837.2 EEQ70987.1 - 0.0052 16.5 12.4 0.0098 15.7 1.5 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain UPF0079 PF02367.12 EEQ70987.1 - 0.0068 16.0 0.1 0.084 12.5 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 EEQ70987.1 - 0.0069 16.7 0.5 0.49 10.6 0.1 2.6 3 0 0 3 3 2 1 AAA domain SRP54 PF00448.17 EEQ70987.1 - 0.011 15.1 2.9 0.21 11.0 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Fer4_10 PF13237.1 EEQ70987.1 - 0.016 14.9 1.5 0.016 14.9 1.0 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_13 PF13166.1 EEQ70987.1 - 0.03 12.8 0.0 0.03 12.8 0.0 2.0 3 0 0 3 3 2 0 AAA domain Thymidylate_kin PF02223.12 EEQ70987.1 - 0.036 13.4 0.0 12 5.2 0.0 2.7 2 0 0 2 2 2 0 Thymidylate kinase NACHT PF05729.7 EEQ70987.1 - 0.038 13.6 2.8 2 8.0 0.0 2.7 3 0 0 3 3 2 0 NACHT domain Fer4_16 PF13484.1 EEQ70987.1 - 0.048 14.3 0.1 0.048 14.3 0.1 2.8 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_28 PF13521.1 EEQ70987.1 - 0.054 13.4 0.1 4.3 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EEQ70987.1 - 0.066 12.3 0.2 0.2 10.7 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_5 PF07728.9 EEQ70987.1 - 0.073 12.7 0.2 3.1 7.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EEQ70987.1 - 0.097 12.1 2.1 0.15 11.5 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 EEQ70987.1 - 0.26 10.8 0.1 5.8 6.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.1 EEQ70987.1 - 0.34 10.9 9.3 0.4 10.7 1.2 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_24 PF13479.1 EEQ70987.1 - 0.38 10.2 3.4 1.8 8.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain Fer4_7 PF12838.2 EEQ70987.1 - 0.4 11.1 13.3 0.042 14.2 1.4 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 EEQ70987.1 - 0.85 9.9 13.6 0.06 13.6 1.5 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 EEQ70987.1 - 2.8 8.0 13.1 0.57 10.2 1.9 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain FF PF01846.14 EEQ70988.1 - 1.5e-41 140.0 20.4 4e-15 55.4 0.5 7.2 6 2 0 6 6 6 6 FF domain WW PF00397.21 EEQ70988.1 - 1.8e-17 62.8 14.6 1.9e-09 37.1 1.1 2.6 2 0 0 2 2 2 2 WW domain Trs65 PF12735.2 EEQ70989.1 - 1.2e-94 317.1 0.0 1.6e-94 316.7 0.0 1.2 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Mpv17_PMP22 PF04117.7 EEQ70990.1 - 5.6e-23 80.3 0.2 1.8e-22 78.7 0.1 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family PGK PF00162.14 EEQ70991.1 - 1.8e-147 490.8 0.1 2.1e-147 490.6 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Dioxygenase_C PF00775.16 EEQ70992.1 - 3e-46 156.9 0.0 3.9e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EEQ70992.1 - 1.9e-11 43.7 0.0 3.2e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EEQ70992.1 - 0.13 12.3 0.0 1.5 8.9 0.0 2.5 2 1 0 2 2 2 0 Carboxypeptidase regulatory-like domain Lactonase PF10282.4 EEQ70993.1 - 4.8e-21 75.2 0.0 6.8e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller WD40 PF00400.27 EEQ70993.1 - 0.02 14.7 0.0 18 5.4 0.0 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat zf-RING_4 PF14570.1 EEQ70997.1 - 4.6 6.9 21.0 0.22 11.1 4.5 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Abhydrolase_6 PF12697.2 EEQ70998.1 - 7.5e-20 71.7 0.1 1.9e-19 70.4 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ70998.1 - 6.8e-13 48.7 0.0 2.5e-10 40.3 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ70998.1 - 2.5e-07 30.5 0.0 6.6e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family EthD PF07110.6 EEQ70998.1 - 3.3e-06 27.9 0.1 0.026 15.4 0.0 2.7 2 0 0 2 2 2 2 EthD domain Esterase PF00756.15 EEQ70998.1 - 0.001 18.5 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.9 EEQ70998.1 - 0.0022 16.5 0.0 0.0052 15.3 0.0 1.7 1 1 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.11 EEQ70998.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DSS1_SEM1 PF05160.8 EEQ70999.1 - 2.4e-25 88.0 14.9 3.4e-25 87.5 10.4 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family DUF3808 PF10300.4 EEQ71000.1 - 2.6e-149 497.7 1.6 3.1e-149 497.5 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) MFS_1 PF07690.11 EEQ71001.1 - 9.8e-35 119.8 35.1 9.8e-35 119.8 24.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ71001.1 - 4.6e-08 32.0 5.3 4.6e-08 32.0 3.6 2.3 1 1 0 2 2 2 1 Sugar (and other) transporter EHN PF06441.7 EEQ71002.1 - 6.6e-15 54.9 0.1 6.3e-14 51.8 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Nup160 PF11715.3 EEQ71003.1 - 1.7e-140 468.7 4.8 2.5e-140 468.2 3.3 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Rad51 PF08423.6 EEQ71004.1 - 9.4e-139 460.5 0.0 1.2e-138 460.2 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EEQ71004.1 - 1.9e-12 46.9 0.0 2.7e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EEQ71004.1 - 2.2e-09 36.8 0.0 3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 EEQ71004.1 - 7e-08 32.5 0.3 2.2e-07 30.9 0.2 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 EEQ71004.1 - 8.2e-06 25.0 0.1 1.6e-05 24.1 0.1 1.5 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.10 EEQ71004.1 - 0.0013 17.6 0.0 0.0025 16.7 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain PAXNEB PF05625.6 EEQ71004.1 - 0.017 13.9 0.1 0.066 12.0 0.0 1.8 2 0 0 2 2 2 0 PAXNEB protein gag_pre-integrs PF13976.1 EEQ71007.1 - 4e-07 29.5 0.2 1.2e-06 27.9 0.1 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain RelB PF04221.7 EEQ71007.1 - 0.036 13.8 0.1 0.13 11.9 0.1 2.0 1 0 0 1 1 1 0 RelB antitoxin DUF3439 PF11921.3 EEQ71008.1 - 0.091 12.5 1.4 0.16 11.7 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pkinase PF00069.20 EEQ71009.1 - 2.1e-27 95.9 0.0 3.3e-27 95.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ71009.1 - 9.6e-12 44.5 0.0 1.6e-10 40.4 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase CPL PF08144.6 EEQ71010.1 - 7e-16 58.4 0.0 2.9e-15 56.3 0.0 2.2 1 0 0 1 1 1 1 CPL (NUC119) domain Nop14 PF04147.7 EEQ71010.1 - 0.0085 14.0 16.7 0.014 13.3 11.6 1.3 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 EEQ71010.1 - 1.5 6.7 16.5 2.2 6.1 11.4 1.2 1 0 0 1 1 1 0 CDC45-like protein PLRV_ORF5 PF01690.12 EEQ71010.1 - 2.1 7.3 10.5 3.3 6.7 7.3 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Trigger_C PF05698.9 EEQ71011.1 - 0.0056 16.5 0.0 0.0056 16.5 0.0 1.7 2 0 0 2 2 2 1 Bacterial trigger factor protein (TF) C-terminus DNA_pol_B_palm PF14792.1 EEQ71013.1 - 1.3e-32 112.1 0.0 6.6e-32 109.8 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 EEQ71013.1 - 2.6e-21 74.9 0.4 8.1e-21 73.3 0.3 1.9 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 EEQ71013.1 - 1.2e-20 72.9 0.0 2.2e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 EEQ71013.1 - 4.4e-17 62.0 0.5 1.3e-16 60.4 0.3 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain BRCT PF00533.21 EEQ71013.1 - 0.00051 20.1 0.1 0.0049 16.9 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.18 EEQ71013.1 - 0.012 15.8 0.0 0.041 14.2 0.0 1.9 1 0 0 1 1 1 0 Nucleotidyltransferase domain HHH_5 PF14520.1 EEQ71013.1 - 0.018 15.2 0.1 10 6.3 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain Herpes_IE1 PF07340.6 EEQ71013.1 - 0.03 12.7 0.1 0.045 12.1 0.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein HHH PF00633.18 EEQ71013.1 - 0.067 12.9 0.2 0.27 11.0 0.1 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif ATP-synt_10 PF05176.9 EEQ71014.1 - 8.2e-94 313.5 0.0 1e-93 313.2 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein V-SNARE_C PF12352.3 EEQ71015.1 - 1.9e-13 50.2 0.3 1.9e-13 50.2 0.2 2.4 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Het-C PF07217.6 EEQ71015.1 - 0.0033 15.7 1.0 0.14 10.3 0.0 2.0 1 1 1 2 2 2 2 Heterokaryon incompatibility protein Het-C Sec20 PF03908.8 EEQ71015.1 - 0.05 13.3 1.3 4.8 6.9 0.0 3.1 2 1 1 3 3 3 0 Sec20 Scaffolding_pro PF11418.3 EEQ71015.1 - 1.3 9.4 4.5 1.1 9.6 0.6 2.3 1 1 1 2 2 2 0 Phi29 scaffolding protein FTA4 PF13093.1 EEQ71015.1 - 1.9 7.8 11.7 15 4.9 8.4 2.0 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Ribosomal_L29 PF00831.18 EEQ71016.1 - 3e-18 65.2 0.6 3e-18 65.2 0.4 2.0 2 1 0 2 2 2 1 Ribosomal L29 protein Cortex-I_coil PF09304.5 EEQ71016.1 - 0.92 9.5 6.6 0.22 11.5 1.5 1.9 1 1 1 2 2 2 0 Cortexillin I, coiled coil FliT PF05400.8 EEQ71016.1 - 1.7 9.1 4.7 1.9 8.9 0.2 2.3 2 1 0 2 2 2 0 Flagellar protein FliT M PF02370.11 EEQ71016.1 - 5.3 7.7 8.4 4.8 7.8 2.5 2.8 2 0 0 2 2 2 0 M protein repeat Med16 PF11635.3 EEQ71017.1 - 4.8e-178 593.5 0.0 2.7e-177 591.1 0.0 1.8 1 1 0 1 1 1 1 Mediator complex subunit 16 SIR2 PF02146.12 EEQ71018.1 - 4.3e-27 94.9 0.0 9.1e-27 93.9 0.0 1.5 1 1 0 1 1 1 1 Sir2 family CBFD_NFYB_HMF PF00808.18 EEQ71019.1 - 7.8e-08 32.2 0.0 1.5e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEQ71019.1 - 0.032 14.3 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Nop14 PF04147.7 EEQ71019.1 - 0.1 10.5 21.4 0.15 9.9 14.8 1.2 1 0 0 1 1 1 0 Nop14-like family GN3L_Grn1 PF08701.6 EEQ71020.1 - 1.1e-25 89.3 14.5 1.1e-25 89.3 10.0 1.9 2 0 0 2 2 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EEQ71020.1 - 1.4e-21 76.6 0.2 5.6e-16 58.5 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEQ71020.1 - 7.5e-07 28.7 0.0 0.029 13.8 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EEQ71020.1 - 2.2e-06 27.6 3.3 0.47 10.2 0.0 3.9 3 1 1 4 4 4 3 Dynamin family FeoB_N PF02421.13 EEQ71020.1 - 2e-05 23.8 0.1 9.6e-05 21.7 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EEQ71020.1 - 0.00013 21.1 0.2 0.00023 20.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EEQ71020.1 - 0.002 18.6 0.2 0.6 10.6 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 EEQ71020.1 - 0.0023 18.2 0.0 0.0023 18.2 0.0 2.6 2 1 0 2 2 1 1 AAA domain ArgK PF03308.11 EEQ71020.1 - 0.018 13.8 0.0 0.043 12.6 0.0 1.5 1 0 0 1 1 1 0 ArgK protein cobW PF02492.14 EEQ71020.1 - 0.039 13.3 0.0 0.76 9.1 0.0 2.6 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ORC3_N PF07034.6 EEQ71020.1 - 0.058 12.3 0.0 0.097 11.6 0.0 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus AAA_16 PF13191.1 EEQ71020.1 - 0.21 11.5 4.6 0.23 11.4 0.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 EEQ71020.1 - 0.46 11.3 0.1 0.46 11.3 0.0 3.0 2 1 0 2 2 1 0 AAA domain Nop14 PF04147.7 EEQ71020.1 - 2 6.2 29.1 3.2 5.5 20.2 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 EEQ71020.1 - 9 5.2 22.6 16 4.4 15.7 1.3 1 0 0 1 1 1 0 BUD22 HAD_2 PF13419.1 EEQ71021.1 - 1.9e-17 64.0 0.0 2.4e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEQ71021.1 - 5.8e-13 49.7 0.0 5.6e-11 43.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ71021.1 - 2.9e-08 33.3 0.0 7.2e-08 32.0 0.0 1.7 1 1 1 2 2 2 1 HAD-hyrolase-like HAD PF12710.2 EEQ71021.1 - 5.7e-05 23.3 0.0 9.2e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EEQ71021.1 - 0.024 14.5 0.0 3.3 7.6 0.0 2.9 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HNH_2 PF13391.1 EEQ71022.1 - 2.5e-13 49.5 1.3 6e-13 48.3 0.1 2.2 2 0 0 2 2 2 1 HNH endonuclease DUF3423 PF11903.3 EEQ71023.1 - 0.071 12.8 0.2 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3423) Kdo PF06293.9 EEQ71024.1 - 7.8e-05 21.8 0.0 0.00015 20.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EEQ71024.1 - 0.0024 17.0 0.0 0.0045 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EEQ71024.1 - 0.011 15.4 3.4 0.011 15.4 0.0 2.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ71024.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase HSDR_N_2 PF13588.1 EEQ71024.1 - 0.061 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Mnd1 PF03962.10 EEQ71024.1 - 0.3 10.7 3.0 0.64 9.6 2.1 1.5 1 0 0 1 1 1 0 Mnd1 family Sugar_tr PF00083.19 EEQ71025.1 - 0.0046 15.5 0.5 0.005 15.4 0.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Bac_rhodopsin PF01036.13 EEQ71025.1 - 0.0084 15.4 0.4 0.0098 15.2 0.3 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF3712 PF12505.3 EEQ71026.1 - 3.3e-24 85.3 0.4 1e-23 83.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) MARVEL PF01284.18 EEQ71026.1 - 1.4e-07 31.3 13.2 1.4e-07 31.3 9.2 1.6 2 0 0 2 2 2 1 Membrane-associating domain Fungal_trans_2 PF11951.3 EEQ71027.1 - 1.9e-06 26.7 0.0 2.6e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain PHD PF00628.24 EEQ71028.1 - 6.7e-10 38.5 6.4 1.4e-09 37.5 4.4 1.5 1 0 0 1 1 1 1 PHD-finger IMD PF08397.6 EEQ71028.1 - 0.26 10.5 3.0 0.11 11.8 0.3 1.6 2 0 0 2 2 2 0 IRSp53/MIM homology domain Aldolase_II PF00596.16 EEQ71031.1 - 3.7e-44 150.5 1.2 4.6e-44 150.2 0.8 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF4160 PF13711.1 EEQ71031.1 - 0.086 12.6 0.2 6.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) Med31 PF05669.7 EEQ71033.1 - 1.7e-28 98.3 0.0 2.2e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 SOH1 FA_desaturase PF00487.19 EEQ71034.1 - 7.6e-40 136.9 24.6 1.3e-39 136.1 17.0 1.5 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EEQ71034.1 - 3.7e-09 36.2 0.0 1.1e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2112 PF09885.4 EEQ71035.1 - 0.02 14.5 0.1 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2112) Pal1 PF08316.6 EEQ71036.1 - 2.7e-48 163.9 5.2 3.3e-48 163.7 0.8 2.7 2 1 0 2 2 2 1 Pal1 cell morphology protein FAD_binding_4 PF01565.18 EEQ71037.1 - 2.4e-17 62.7 2.4 4.6e-17 61.7 1.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEQ71037.1 - 0.0026 17.6 0.1 0.0058 16.5 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Zn_clus PF00172.13 EEQ71038.1 - 0.0031 17.3 7.3 0.0077 16.1 5.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PrsW-protease PF13367.1 EEQ71038.1 - 0.028 13.5 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 Protease prsW family HAD_2 PF13419.1 EEQ71038.1 - 0.15 12.2 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF1561 PF07598.6 EEQ71039.1 - 0.025 12.5 0.0 0.033 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) GST_C PF00043.20 EEQ71039.1 - 0.054 13.4 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Xan_ur_permease PF00860.15 EEQ71040.1 - 5.8e-24 84.3 24.8 7.8e-23 80.5 17.2 2.1 1 1 0 1 1 1 1 Permease family FAM74 PF15026.1 EEQ71041.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 FAM74 protein MAGE PF01454.14 EEQ71042.1 - 8.1e-40 136.2 0.0 1.2e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 MAGE family Bd3614-deam PF14439.1 EEQ71042.1 - 0.093 12.5 2.2 0.12 12.2 0.4 2.1 2 0 0 2 2 2 0 Bd3614-like deaminase Cut8_N PF14482.1 EEQ71042.1 - 6.8 6.7 14.5 3.2 7.8 7.0 2.3 1 1 1 2 2 2 0 Cut8 proteasome-binding domain Ank_2 PF12796.2 EEQ71043.1 - 8.6e-05 22.8 0.1 0.00026 21.2 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEQ71043.1 - 0.00029 20.9 0.2 0.19 11.9 0.0 3.2 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ71043.1 - 0.00053 19.9 0.2 0.01 16.0 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 EEQ71043.1 - 0.0081 15.9 0.0 0.032 14.0 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat TFIIS_C PF01096.13 EEQ71044.1 - 1.5e-13 50.0 7.8 1.9e-13 49.8 0.2 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EEQ71044.1 - 1e-05 25.1 4.7 1.1e-05 24.9 1.6 2.3 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 EEQ71044.1 - 0.009 15.8 1.9 0.11 12.3 0.3 2.3 2 0 0 2 2 2 1 Transposase zinc-ribbon domain IBR PF01485.16 EEQ71044.1 - 0.034 14.0 1.2 2.4 8.0 0.2 2.2 2 0 0 2 2 2 0 IBR domain zf-TFIIB PF13453.1 EEQ71044.1 - 2.4 7.4 5.2 0.47 9.6 0.6 2.0 2 0 0 2 2 2 0 Transcription factor zinc-finger GTP_EFTU PF00009.22 EEQ71045.1 - 7.7e-57 191.7 0.0 1.2e-56 191.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EEQ71045.1 - 6.3e-37 125.7 0.1 1.9e-36 124.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EEQ71045.1 - 2.2e-16 59.6 1.1 7e-16 58.1 0.8 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EEQ71045.1 - 4.5e-05 22.9 0.3 4.5e-05 22.9 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EEQ71045.1 - 0.0028 17.5 0.2 0.0074 16.2 0.2 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EEQ71045.1 - 0.12 12.1 0.4 15 5.3 0.0 2.5 1 1 1 2 2 2 0 Dynamin family DUF3210 PF11489.3 EEQ71047.1 - 2.2e-217 724.1 76.9 2.2e-217 724.1 53.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3210) DUF1765 PF08578.5 EEQ71048.1 - 2.3e-43 147.2 4.7 7e-43 145.6 3.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) ATP_sub_h PF10775.4 EEQ71049.1 - 1.4e-25 88.7 2.1 1.9e-25 88.3 1.5 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EEQ71049.1 - 0.022 14.6 0.1 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 TFIIB PF00382.14 EEQ71050.1 - 4.3e-39 132.1 0.0 1.2e-20 73.0 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EEQ71050.1 - 3.7e-10 38.9 0.7 3.7e-10 38.9 0.5 1.7 2 0 0 2 2 2 1 TFIIB zinc-binding RB_B PF01857.15 EEQ71050.1 - 0.056 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain Sigma70_r4_2 PF08281.7 EEQ71050.1 - 0.16 11.4 0.0 0.45 10.0 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 TFR_dimer PF04253.10 EEQ71051.1 - 3.6e-31 107.3 0.1 5.6e-31 106.7 0.1 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EEQ71051.1 - 9.1e-18 64.6 0.0 3e-17 62.9 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 EEQ71051.1 - 5.1e-08 32.5 0.0 9.7e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 EEQ71051.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Nicastrin PKI PF02827.11 EEQ71051.1 - 0.12 12.4 0.2 0.31 11.1 0.2 1.6 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor HMG_CoA_synt_C PF08540.5 EEQ71053.1 - 2.7e-101 338.7 1.7 8.1e-99 330.6 1.2 2.1 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EEQ71053.1 - 5.2e-95 315.8 0.3 8.3e-95 315.2 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal GFO_IDH_MocA PF01408.17 EEQ71056.1 - 1.5e-13 51.3 0.0 2.8e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EEQ71056.1 - 0.00078 19.2 1.1 0.001 18.8 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain PGM_PMM_I PF02878.11 EEQ71057.1 - 4.8e-34 116.8 0.0 7.3e-34 116.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EEQ71057.1 - 2e-24 85.8 0.0 3.6e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EEQ71057.1 - 1.3e-16 60.8 0.1 3.9e-16 59.2 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EEQ71057.1 - 1.1e-09 38.1 0.0 2.4e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_T PF00929.19 EEQ71058.1 - 2.3e-19 70.2 0.0 2.6e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Exonuclease NDUF_B12 PF08122.7 EEQ71059.1 - 0.21 11.3 0.2 0.21 11.3 0.1 2.3 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Mucin PF01456.12 EEQ71060.1 - 0.48 10.1 23.1 0.17 11.6 12.6 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Sugar_tr PF00083.19 EEQ71062.1 - 1.1e-90 304.4 21.0 1.4e-90 304.0 14.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ71062.1 - 1.6e-14 53.4 30.4 1.6e-14 53.4 21.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NapB PF03892.9 EEQ71063.1 - 0.095 12.3 2.1 0.11 12.1 1.3 1.2 1 1 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) Oxysterol_BP PF01237.13 EEQ71064.1 - 1.2e-86 290.4 0.1 1.4e-86 290.2 0.1 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Kinesin-relat_1 PF12711.2 EEQ71064.1 - 0.03 14.7 0.1 0.086 13.2 0.0 1.7 2 0 0 2 2 2 0 Kinesin motor RTA1 PF04479.8 EEQ71065.1 - 6.3e-28 97.7 10.2 8.9e-28 97.3 7.1 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF788 PF05620.6 EEQ71065.1 - 0.0019 18.0 0.0 0.0019 18.0 0.0 3.0 4 0 0 4 4 4 1 Protein of unknown function (DUF788) Macoilin PF09726.4 EEQ71065.1 - 0.043 12.0 1.8 0.062 11.5 1.3 1.2 1 0 0 1 1 1 0 Transmembrane protein Scs3p PF10261.4 EEQ71065.1 - 0.11 11.5 2.5 18 4.2 2.6 2.3 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM TAF4 PF05236.9 EEQ71065.1 - 0.28 10.4 4.5 0.41 9.8 3.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DEDD_Tnp_IS110 PF01548.12 EEQ71065.1 - 1.6 8.4 4.3 2.6 7.7 3.0 1.2 1 0 0 1 1 1 0 Transposase Med19 PF10278.4 EEQ71065.1 - 3.2 7.3 12.6 4.9 6.7 8.7 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 NARP1 PF12569.3 EEQ71065.1 - 7.7 5.1 8.6 10 4.6 6.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CUE PF02845.11 EEQ71066.1 - 5.8e-10 38.4 0.1 8.6e-10 37.9 0.0 1.3 1 0 0 1 1 1 1 CUE domain MSP1_C PF07462.6 EEQ71066.1 - 8.2 4.6 5.6 19 3.4 3.9 1.5 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Ank_2 PF12796.2 EEQ71068.1 - 6e-45 151.5 2.8 4.8e-11 42.8 0.0 4.9 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ71068.1 - 1.4e-40 135.0 1.2 3.6e-05 23.3 0.0 9.4 8 2 1 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 EEQ71068.1 - 4.4e-30 103.4 0.1 6e-08 32.9 0.0 7.5 4 3 3 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ71068.1 - 2.5e-27 92.2 0.4 0.00035 20.5 0.0 9.3 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 EEQ71068.1 - 7.2e-24 83.2 2.7 0.00053 20.1 0.0 7.6 4 1 4 8 8 8 5 Ankyrin repeats (many copies) EVI2A PF05399.6 EEQ71069.1 - 5.1 6.2 8.9 0.36 10.0 2.3 1.7 1 1 1 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) UCH PF00443.24 EEQ71070.1 - 3.9e-41 140.9 0.3 2.5e-34 118.6 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEQ71070.1 - 4.4e-12 46.0 1.3 7.3e-11 42.0 0.9 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase InaF-motif PF15018.1 EEQ71070.1 - 0.39 10.1 1.1 0.87 9.0 0.8 1.6 1 0 0 1 1 1 0 TRP-interacting helix Methyltransf_23 PF13489.1 EEQ71071.1 - 1.3e-20 73.7 0.0 1.8e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ71071.1 - 7.5e-10 38.5 0.0 6.8e-09 35.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ71071.1 - 6.4e-09 36.3 0.0 9.8e-08 32.5 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ71071.1 - 1.9e-06 28.2 0.0 3.9e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ71071.1 - 4.7e-06 27.0 0.0 0.00011 22.5 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEQ71071.1 - 0.0025 16.9 0.0 0.072 12.1 0.0 2.4 2 1 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 EEQ71071.1 - 0.004 17.1 0.0 0.023 14.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EEQ71071.1 - 0.0082 15.2 0.0 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EEQ71071.1 - 0.023 14.0 0.0 0.086 12.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_25 PF13649.1 EEQ71071.1 - 0.035 14.4 0.0 0.078 13.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EEQ71071.1 - 0.044 13.7 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EEQ71071.1 - 0.16 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase F_bP_aldolase PF01116.15 EEQ71072.1 - 1.3e-96 323.0 0.0 1.5e-96 322.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF221 PF02714.10 EEQ71074.1 - 7.1e-93 311.0 22.5 1.1e-92 310.3 15.6 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EEQ71074.1 - 5.4e-40 136.5 1.1 5.4e-40 136.5 0.7 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EEQ71074.1 - 1.5e-16 60.6 0.1 4.1e-16 59.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Excalibur PF05901.6 EEQ71075.1 - 0.41 11.0 3.7 1.4 9.2 0.5 2.2 2 0 0 2 2 2 0 Excalibur calcium-binding domain PspC PF04024.7 EEQ71075.1 - 2 7.9 5.4 3.1 7.3 3.7 1.3 1 0 0 1 1 1 0 PspC domain Brevenin PF03032.10 EEQ71077.1 - 0.047 13.5 0.4 7.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Brevenin/esculentin/gaegurin/rugosin family DUF3445 PF11927.3 EEQ71079.1 - 7e-89 297.4 0.0 8.8e-89 297.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Iron_permease PF04120.7 EEQ71079.1 - 0.017 14.6 0.2 0.05 13.1 0.0 1.8 2 1 0 2 2 2 0 Low affinity iron permease Homoserine_dh PF00742.14 EEQ71080.1 - 5.5e-51 172.7 0.0 7.2e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EEQ71080.1 - 1.4e-10 41.5 0.0 6e-10 39.5 0.0 2.0 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF1010 PF06231.6 EEQ71080.1 - 4.6 7.3 9.0 0.58 10.1 2.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1010) DUF4078 PF13300.1 EEQ71081.1 - 1.1e-30 105.5 10.8 1.1e-30 105.5 7.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4078) ATG11 PF10377.4 EEQ71082.1 - 2e-42 144.1 1.6 9.6e-42 141.9 0.0 3.0 2 0 0 2 2 2 1 Autophagy-related protein 11 APG17 PF04108.7 EEQ71082.1 - 5e-05 22.2 0.4 5e-05 22.2 0.3 5.5 3 2 1 5 5 5 2 Autophagy protein Apg17 DUF869 PF05911.6 EEQ71082.1 - 0.00092 17.5 6.5 0.00092 17.5 4.5 5.0 2 2 1 4 4 4 1 Plant protein of unknown function (DUF869) ApoO PF09769.4 EEQ71082.1 - 9.5 5.9 19.2 0.99 9.0 1.9 4.2 3 2 1 4 4 4 0 Apolipoprotein O CENP-H PF05837.7 EEQ71083.1 - 9.3e-24 83.6 8.0 1.8e-23 82.7 2.4 2.2 2 0 0 2 2 2 1 Centromere protein H (CENP-H) Resolvase PF00239.16 EEQ71083.1 - 0.083 12.7 4.8 0.093 12.5 0.3 2.5 2 1 0 2 2 2 0 Resolvase, N terminal domain DUF2031 PF09592.5 EEQ71083.1 - 0.11 11.6 0.1 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) HMG_box PF00505.14 EEQ71085.1 - 1.3e-24 86.2 1.0 2e-24 85.6 0.7 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EEQ71085.1 - 5.9e-19 68.1 1.6 9.2e-19 67.5 1.1 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EEQ71085.1 - 0.00035 20.2 0.6 0.00076 19.2 0.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 EEQ71085.1 - 0.027 14.6 0.4 0.083 13.0 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) Herpes_UL6 PF01763.11 EEQ71088.1 - 0.4 8.7 2.7 0.61 8.1 1.9 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF506 PF04720.7 EEQ71088.1 - 1 8.9 4.1 2.2 7.8 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF506) DNA_pol_phi PF04931.8 EEQ71088.1 - 2.8 5.6 9.6 4.1 5.0 6.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi SKG6 PF08693.5 EEQ71089.1 - 0.023 13.9 0.0 0.039 13.2 0.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Granulin PF00396.13 EEQ71089.1 - 1.8 8.7 21.6 4.7 7.4 3.9 2.4 2 0 0 2 2 2 0 Granulin Abhydrolase_3 PF07859.8 EEQ71090.1 - 1.9e-38 132.2 0.0 1.9e-37 128.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ71090.1 - 0.0056 16.4 0.0 0.0077 15.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EEQ71090.1 - 0.021 13.4 0.1 0.2 10.2 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) GMC_oxred_N PF00732.14 EEQ71091.1 - 5.3e-56 189.9 0.0 1.5e-54 185.1 0.0 2.3 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EEQ71091.1 - 1.9e-37 128.7 0.0 3.4e-37 127.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EEQ71091.1 - 5.2e-05 22.3 0.2 7.9e-05 21.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EEQ71091.1 - 9e-05 21.5 0.4 0.00016 20.6 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EEQ71091.1 - 0.00099 18.2 0.5 0.0041 16.2 0.2 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EEQ71091.1 - 0.0029 17.5 0.2 0.0076 16.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EEQ71091.1 - 0.045 12.3 0.5 0.067 11.7 0.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EEQ71091.1 - 0.049 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EEQ71091.1 - 0.12 10.8 0.5 0.19 10.1 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 EEQ71091.1 - 0.16 10.7 0.4 0.28 9.9 0.1 1.5 2 0 0 2 2 2 0 FAD binding domain Desulfoferrodox PF01880.13 EEQ71092.1 - 0.053 13.8 0.0 0.08 13.2 0.0 1.3 1 0 0 1 1 1 0 Desulfoferrodoxin DnaJ PF00226.26 EEQ71093.1 - 1.3e-08 34.4 1.5 2.7e-08 33.4 1.0 1.6 1 0 0 1 1 1 1 DnaJ domain FHA PF00498.21 EEQ71094.1 - 1.1e-12 47.8 0.0 2.1e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 FHA domain YtxH PF12732.2 EEQ71095.1 - 0.94 9.8 13.3 73 3.8 9.2 2.1 1 1 0 1 1 1 0 YtxH-like protein DUF883 PF05957.8 EEQ71095.1 - 1.3 9.4 8.7 2.9 8.3 4.1 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) LUC7 PF03194.10 EEQ71095.1 - 1.3 8.4 7.2 1.7 8.1 5.0 1.0 1 0 0 1 1 1 0 LUC7 N_terminus DUF4320 PF14208.1 EEQ71095.1 - 2.1 8.3 4.5 1.7 8.6 1.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4320) LEA_4 PF02987.11 EEQ71095.1 - 5.2 7.0 24.8 0.22 11.3 10.3 2.6 2 2 0 2 2 2 0 Late embryogenesis abundant protein NB-ARC PF00931.17 EEQ71096.1 - 3.3e-12 45.8 0.0 5.1e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EEQ71096.1 - 4.9e-06 26.6 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Abhydrolase_6 PF12697.2 EEQ71096.1 - 0.00022 21.1 0.0 0.00042 20.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EEQ71096.1 - 0.00098 18.7 0.0 0.0026 17.3 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein Arch_ATPase PF01637.13 EEQ71096.1 - 0.002 17.8 0.0 0.0035 17.0 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EEQ71096.1 - 0.0026 17.4 0.0 0.047 13.3 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EEQ71096.1 - 0.0027 17.8 0.0 0.0073 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EEQ71096.1 - 0.007 15.8 0.0 0.021 14.2 0.0 1.8 2 0 0 2 2 2 1 AAA-like domain KaiC PF06745.8 EEQ71096.1 - 0.0082 15.2 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_33 PF13671.1 EEQ71096.1 - 0.015 15.2 0.0 0.045 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EEQ71096.1 - 0.025 15.4 0.0 0.071 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EEQ71096.1 - 0.039 13.4 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF676 PF05057.9 EEQ71096.1 - 0.04 13.2 0.2 0.11 11.7 0.1 1.7 1 1 0 1 1 1 0 Putative serine esterase (DUF676) AFG1_ATPase PF03969.11 EEQ71096.1 - 0.042 12.6 0.0 0.067 11.9 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase Zeta_toxin PF06414.7 EEQ71096.1 - 0.12 11.4 0.2 0.92 8.5 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin CobU PF02283.11 EEQ71096.1 - 0.2 11.0 0.2 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase ECH PF00378.15 EEQ71097.1 - 1.8e-50 171.3 0.2 2.2e-50 171.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pox_P21 PF05313.7 EEQ71097.1 - 0.035 13.3 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P21 membrane protein DUF1087 PF06465.8 EEQ71100.1 - 0.051 13.4 0.3 0.13 12.2 0.2 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) DUF964 PF06133.6 EEQ71100.1 - 0.093 12.7 2.5 0.15 12.0 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF964) RWD PF05773.17 EEQ71100.1 - 7.8 6.4 8.0 4.8 7.1 1.5 2.9 2 1 1 3 3 3 0 RWD domain GatB_N PF02934.10 EEQ71103.1 - 2.1e-98 328.7 0.0 2.8e-98 328.3 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EEQ71103.1 - 5.6e-25 87.7 0.0 9.9e-25 86.9 0.0 1.4 1 0 0 1 1 1 1 GatB domain Arginase PF00491.16 EEQ71104.1 - 4.4e-79 265.6 0.5 5.1e-79 265.4 0.4 1.0 1 0 0 1 1 1 1 Arginase family Cortexin PF11057.3 EEQ71105.1 - 0.0025 17.3 1.3 0.0087 15.6 0.0 2.2 2 0 0 2 2 2 1 Cortexin of kidney Asp PF00026.18 EEQ71106.1 - 1.1e-109 366.5 0.0 1.4e-109 366.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EEQ71106.1 - 8.8e-12 45.2 0.0 3.3e-11 43.4 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EEQ71106.1 - 3.8e-06 27.3 0.5 0.054 13.9 0.0 3.5 3 2 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EEQ71106.1 - 0.00015 21.3 0.0 0.0015 18.0 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Alpha-amylase_C PF02806.13 EEQ71106.1 - 0.061 13.4 0.0 0.19 11.8 0.0 1.9 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain gag-asp_proteas PF13975.1 EEQ71106.1 - 0.083 12.7 0.0 4.2 7.2 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease NIF PF03031.13 EEQ71107.1 - 2.9e-26 92.0 0.3 6.8e-26 90.8 0.0 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EEQ71107.1 - 1.5e-11 43.9 0.1 2.8e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EEQ71107.1 - 2e-09 37.4 0.0 8.3e-09 35.4 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EEQ71108.1 - 2.8e-45 153.7 0.5 6.6e-45 152.5 0.0 1.9 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEQ71108.1 - 3.5e-09 36.5 0.1 1.2e-08 34.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EEQ71108.1 - 4.2e-08 33.2 0.0 9e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EEQ71108.1 - 4.9e-07 29.9 0.0 1.5e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEQ71108.1 - 8.8e-07 29.1 0.6 0.001 19.1 0.0 2.7 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 EEQ71108.1 - 9.7e-07 27.9 0.0 2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EEQ71108.1 - 7.6e-05 22.6 0.0 0.00058 19.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EEQ71108.1 - 0.00029 21.6 0.0 0.0019 18.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EEQ71108.1 - 0.00035 19.6 0.0 0.00081 18.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EEQ71108.1 - 0.00045 20.2 0.0 0.00088 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EEQ71108.1 - 0.00051 18.8 0.0 0.00091 18.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus NACHT PF05729.7 EEQ71108.1 - 0.00097 18.8 0.2 0.056 13.0 0.0 2.7 2 1 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.7 EEQ71108.1 - 0.0012 18.0 0.1 0.0038 16.3 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 EEQ71108.1 - 0.0014 18.2 0.2 0.0035 17.0 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 EEQ71108.1 - 0.0015 18.6 0.0 0.0033 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.10 EEQ71108.1 - 0.0033 17.1 0.0 0.0093 15.6 0.0 1.8 1 0 0 1 1 1 1 NTPase AAA_3 PF07726.6 EEQ71108.1 - 0.0036 16.9 0.0 0.011 15.2 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EEQ71108.1 - 0.0046 16.5 0.0 0.039 13.5 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 EEQ71108.1 - 0.0054 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEQ71108.1 - 0.006 16.1 0.0 0.016 14.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EEQ71108.1 - 0.007 15.5 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EEQ71108.1 - 0.0088 15.7 0.8 0.06 13.0 0.0 2.5 2 1 1 3 3 3 1 Archaeal ATPase IstB_IS21 PF01695.12 EEQ71108.1 - 0.0098 15.3 0.3 0.024 14.0 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_30 PF13604.1 EEQ71108.1 - 0.0099 15.4 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EEQ71108.1 - 0.013 15.0 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EEQ71108.1 - 0.017 15.4 0.2 0.81 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 EEQ71108.1 - 0.019 14.6 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_25 PF13481.1 EEQ71108.1 - 0.023 14.1 2.9 0.078 12.3 0.1 2.5 2 1 1 3 3 3 0 AAA domain KaiC PF06745.8 EEQ71108.1 - 0.025 13.6 0.7 0.46 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC AAA_18 PF13238.1 EEQ71108.1 - 0.028 14.7 0.1 0.096 12.9 0.0 2.0 2 1 0 2 2 1 0 AAA domain Sigma54_activat PF00158.21 EEQ71108.1 - 0.047 13.1 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EEQ71108.1 - 0.068 13.2 0.1 0.31 11.0 0.0 2.2 2 1 0 2 2 1 0 Sigma-54 interaction domain Viral_Hsp90 PF03225.9 EEQ71108.1 - 0.11 10.7 0.0 0.16 10.1 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue NB-ARC PF00931.17 EEQ71108.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 EEQ71108.1 - 0.17 10.6 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PfkB PF00294.19 EEQ71109.1 - 3.4e-20 72.4 0.0 2.1e-19 69.8 0.0 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase NIF PF03031.13 EEQ71109.1 - 0.094 12.3 0.0 0.47 10.1 0.0 2.0 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase ARID PF01388.16 EEQ71111.1 - 5.2e-18 64.6 0.0 1e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Img2 PF05046.9 EEQ71112.1 - 2.1e-28 98.3 0.0 4e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Allexi_40kDa PF05549.6 EEQ71112.1 - 0.061 12.6 0.9 0.073 12.3 0.6 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein eIF3_N PF09440.5 EEQ71113.1 - 8.1e-54 181.3 5.0 1.8e-53 180.2 3.4 1.6 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EEQ71113.1 - 1.3e-14 54.3 0.2 1.2e-13 51.2 0.0 2.7 3 1 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EEQ71113.1 - 0.007 16.1 0.0 0.028 14.2 0.0 2.0 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 RPN7 PF10602.4 EEQ71113.1 - 0.038 13.3 0.8 0.08 12.3 0.1 1.8 1 1 1 2 2 2 0 26S proteasome subunit RPN7 DUF2683 PF10884.3 EEQ71113.1 - 0.052 13.4 2.0 0.17 11.8 1.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) NYD-SP28 PF14772.1 EEQ71113.1 - 0.06 13.4 2.4 0.21 11.7 1.7 1.9 1 0 0 1 1 1 0 Sperm tail zf-ZPR1 PF03367.8 EEQ71113.1 - 0.11 11.7 0.4 0.28 10.3 0.3 1.7 1 0 0 1 1 1 0 ZPR1 zinc-finger domain Atg14 PF10186.4 EEQ71115.1 - 0.014 14.4 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ArsA_ATPase PF02374.10 EEQ71117.1 - 2e-114 381.7 0.0 2.3e-114 381.5 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EEQ71117.1 - 7.2e-18 64.6 0.3 1.2e-17 63.9 0.2 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EEQ71117.1 - 1.2e-08 34.9 0.0 1.6e-07 31.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 EEQ71117.1 - 1.7e-06 27.4 0.1 4.7e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EEQ71117.1 - 1e-05 25.0 0.8 0.00079 18.9 0.0 2.6 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EEQ71117.1 - 0.0018 17.7 0.2 0.0071 15.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ71117.1 - 0.0084 15.8 0.0 0.024 14.4 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain NB-ARC PF00931.17 EEQ71117.1 - 0.0091 14.8 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain MipZ PF09140.6 EEQ71117.1 - 0.011 14.7 0.1 0.033 13.2 0.0 1.7 2 0 0 2 2 2 0 ATPase MipZ PhoH PF02562.11 EEQ71117.1 - 0.02 14.1 0.1 0.052 12.7 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein YhjQ PF06564.7 EEQ71117.1 - 0.021 14.2 0.0 0.061 12.6 0.0 1.7 2 0 0 2 2 2 0 YhjQ protein IstB_IS21 PF01695.12 EEQ71117.1 - 0.025 14.0 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AIP3 PF03915.8 EEQ71117.1 - 0.095 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 Transthyretin PF00576.16 EEQ71118.1 - 3.2e-17 62.4 0.0 6.4e-11 42.1 0.0 2.4 2 1 0 2 2 2 2 HIUase/Transthyretin family Mucin PF01456.12 EEQ71118.1 - 0.058 13.1 15.0 0.082 12.6 10.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 EEQ71118.1 - 0.12 10.3 8.4 0.14 10.0 5.8 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MGC-24 PF05283.6 EEQ71118.1 - 5.1 6.8 14.0 8.5 6.1 9.7 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Aft1_HRA PF11786.3 EEQ71119.1 - 7.7e-26 90.1 9.8 3e-25 88.2 6.8 2.1 1 0 0 1 1 1 1 Aft1 HRA domain Aft1_HRR PF11787.3 EEQ71119.1 - 5.3e-24 85.0 5.5 5.3e-24 85.0 3.8 4.9 3 2 1 4 4 4 1 Aft1 HRR domain Aft1_OSA PF11785.3 EEQ71119.1 - 9.7e-17 61.2 20.5 9.7e-17 61.2 14.2 4.1 4 1 0 4 4 4 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.16 EEQ71119.1 - 6.9e-13 48.3 5.6 1.4e-12 47.3 3.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEQ71119.1 - 4.4e-07 29.6 5.6 4.4e-07 29.6 3.9 2.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EEQ71119.1 - 0.0015 18.8 3.4 0.0015 18.8 2.4 2.7 2 0 0 2 2 2 1 bZIP Maf transcription factor Prp18 PF02840.10 EEQ71119.1 - 0.094 12.5 0.2 0.094 12.5 0.1 2.0 2 1 0 2 2 2 0 Prp18 domain Spc97_Spc98 PF04130.8 EEQ71120.1 - 3.5e-116 388.6 0.0 4.8e-116 388.2 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF2373 PF10180.4 EEQ71121.1 - 3.7e-22 77.6 0.0 1e-21 76.2 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) Proteasome PF00227.21 EEQ71122.1 - 1.5e-48 164.6 0.0 2e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEQ71122.1 - 5e-13 48.0 0.3 9e-13 47.2 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SCP2 PF02036.12 EEQ71122.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 SCP-2 sterol transfer family DUF3650 PF12368.3 EEQ71122.1 - 0.12 11.9 0.6 0.12 11.9 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) Ribosomal_L27e PF01777.13 EEQ71125.1 - 7.8e-38 128.4 2.9 1e-37 128.1 2.0 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EEQ71125.1 - 0.00057 19.4 0.1 0.002 17.7 0.1 2.0 1 0 0 1 1 1 1 KOW motif SMAP PF15477.1 EEQ71125.1 - 0.2 11.9 1.6 0.49 10.7 1.1 1.6 1 1 0 1 1 1 0 Small acidic protein family LPP PF04728.8 EEQ71126.1 - 0.014 15.1 7.3 0.039 13.7 0.5 4.4 4 0 0 4 4 4 0 Lipoprotein leucine-zipper TRAM_LAG1_CLN8 PF03798.11 EEQ71127.1 - 1.9e-47 161.4 17.3 1.9e-47 161.4 12.0 1.4 2 0 0 2 2 2 1 TLC domain COX2_TM PF02790.10 EEQ71127.1 - 0.004 17.0 0.1 0.83 9.6 0.0 2.6 2 0 0 2 2 2 2 Cytochrome C oxidase subunit II, transmembrane domain Rotamase PF00639.16 EEQ71127.1 - 0.038 14.7 0.2 0.073 13.8 0.1 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain NfeD PF01957.13 EEQ71127.1 - 0.051 13.7 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding Adeno_E4_34 PF04528.8 EEQ71127.1 - 0.14 11.7 0.3 0.39 10.3 0.1 1.8 2 0 0 2 2 2 0 Adenovirus early E4 34 kDa protein conserved region PHD PF00628.24 EEQ71128.1 - 1.1e-09 37.8 7.8 2.3e-09 36.7 5.4 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EEQ71128.1 - 1.2 8.5 9.6 0.45 9.8 3.1 2.5 2 1 0 2 2 2 0 PHD-finger C1_1 PF00130.17 EEQ71128.1 - 1.5 8.6 6.9 0.2 11.4 1.6 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EEQ71128.1 - 2.9 7.6 7.9 0.29 10.8 2.2 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF2838 PF10998.3 EEQ71129.1 - 5.9 6.8 16.4 1.7 8.5 6.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2838) Histone PF00125.19 EEQ71130.1 - 0.005 16.9 0.6 0.0081 16.2 0.1 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 hSac2 PF12456.3 EEQ71130.1 - 0.066 12.6 0.5 0.086 12.2 0.3 1.3 1 1 0 1 1 1 0 Inositol phosphatase CoA_transf_3 PF02515.12 EEQ71131.1 - 2.7e-60 202.8 0.0 3.6e-60 202.4 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Lum_binding PF00677.12 EEQ71132.1 - 4.2e-39 132.3 0.6 1.2e-22 79.5 0.1 2.1 2 0 0 2 2 2 2 Lumazine binding domain Brix PF04427.13 EEQ71133.1 - 2.3e-56 190.5 0.3 3.2e-56 190.0 0.2 1.2 1 0 0 1 1 1 1 Brix domain SLX9 PF15341.1 EEQ71133.1 - 0.033 14.6 1.4 0.033 14.6 1.0 3.1 3 1 0 3 3 3 0 Ribosome biogenesis protein SLX9 TT_ORF2 PF02957.10 EEQ71133.1 - 0.41 11.3 11.6 0.073 13.7 5.1 2.0 2 0 0 2 2 2 0 TT viral ORF2 DEAD PF00270.24 EEQ71134.1 - 3.2e-46 156.9 0.0 5.2e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ71134.1 - 2.8e-26 91.1 0.0 6.4e-26 90.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ71134.1 - 0.0022 17.8 0.0 0.015 15.1 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PGM_PMM_I PF02878.11 EEQ71135.1 - 2.9e-16 59.1 0.0 1.4e-08 34.3 0.0 2.7 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EEQ71135.1 - 3.6e-16 59.3 0.1 1.4e-15 57.5 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EEQ71135.1 - 1.1e-10 41.3 1.4 2.1e-10 40.4 0.4 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EEQ71135.1 - 0.0021 18.1 0.1 0.0051 16.8 0.1 1.8 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Per1 PF04080.8 EEQ71136.1 - 9.4e-107 356.4 8.8 1.2e-106 356.0 6.1 1.1 1 0 0 1 1 1 1 Per1-like Methyltransf_31 PF13847.1 EEQ71137.1 - 5.7e-12 45.4 0.0 8.8e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EEQ71137.1 - 5.8e-11 42.0 0.0 1e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EEQ71137.1 - 6.5e-10 39.0 0.0 1.2e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ71137.1 - 2e-09 37.9 0.0 3.4e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EEQ71137.1 - 7e-09 35.1 0.0 1.4e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 EEQ71137.1 - 8.4e-08 32.5 0.0 1.6e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EEQ71137.1 - 1.6e-06 27.0 0.1 2.4e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.1 EEQ71137.1 - 3.4e-06 26.8 0.0 6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ71137.1 - 4.9e-06 26.8 0.0 1.5e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EEQ71137.1 - 1.1e-05 24.6 0.0 1.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EEQ71137.1 - 3.3e-05 23.3 0.0 5.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 EEQ71137.1 - 0.00052 20.0 0.0 0.00089 19.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.7 EEQ71137.1 - 0.00057 20.3 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EEQ71137.1 - 0.0051 16.2 0.0 0.0077 15.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 EEQ71137.1 - 0.014 15.0 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EEQ71137.1 - 0.028 13.9 0.2 0.051 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EEQ71137.1 - 0.038 13.1 0.1 0.078 12.0 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MaoC_dehydratas PF01575.14 EEQ71138.1 - 2.9e-20 71.8 0.0 6.7e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EEQ71138.1 - 5.3e-10 39.2 0.0 3.7e-09 36.4 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase TauD PF02668.11 EEQ71139.1 - 7.5e-39 133.9 0.1 2e-38 132.5 0.0 1.6 1 1 1 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EEQ71139.1 - 3.9e-06 27.1 0.0 7.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.5 EEQ71139.1 - 0.041 12.7 0.1 3.6 6.4 0.0 2.2 2 0 0 2 2 2 0 CsiD AAA PF00004.24 EEQ71140.1 - 2.3e-38 131.3 0.1 6.3e-38 129.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEQ71140.1 - 0.0048 16.6 1.9 0.026 14.2 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EEQ71140.1 - 0.012 15.5 2.6 0.03 14.2 0.0 2.9 2 2 1 3 3 3 0 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EEQ71140.1 - 0.018 14.1 0.0 0.063 12.3 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 EEQ71140.1 - 0.032 13.4 0.1 0.49 9.5 0.0 2.4 3 0 0 3 3 3 0 PhoH-like protein AAA_22 PF13401.1 EEQ71140.1 - 0.42 10.7 2.7 5.2 7.2 0.0 3.0 2 1 0 3 3 3 0 AAA domain F-box-like PF12937.2 EEQ71141.1 - 0.0024 17.5 0.1 0.012 15.2 0.0 2.4 2 0 0 2 2 2 1 F-box-like Pkinase PF00069.20 EEQ71143.1 - 1.8e-72 243.5 0.0 3.1e-72 242.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ71143.1 - 8.5e-32 110.2 0.0 1.2e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EEQ71143.1 - 1.4e-11 44.6 0.0 1.4e-11 44.6 0.0 3.6 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EEQ71143.1 - 1.5e-09 37.2 0.1 2.8e-09 36.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 EEQ71143.1 - 0.0021 17.8 0.2 0.075 12.8 0.1 2.6 2 0 0 2 2 2 1 C2 domain APH PF01636.18 EEQ71143.1 - 0.0036 17.0 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EEQ71143.1 - 0.046 13.0 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EEQ71143.1 - 0.12 11.3 0.1 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SR-25 PF10500.4 EEQ71144.1 - 0.47 9.8 14.2 0.58 9.5 9.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Chorion_2 PF03964.10 EEQ71144.1 - 3.9 8.0 13.6 7.9 7.1 9.4 1.6 1 1 0 1 1 1 0 Chorion family 2 DUF4246 PF14033.1 EEQ71145.1 - 5.5e-191 635.5 0.1 6.5e-191 635.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EEQ71145.1 - 0.0029 17.8 0.0 0.012 15.8 0.0 2.0 2 0 0 2 2 2 1 Putative 2OG-Fe(II) oxygenase CRC_subunit PF08624.5 EEQ71146.1 - 2.1e-57 192.9 0.0 3e-57 192.4 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit TrkH PF02386.11 EEQ71147.1 - 2.2e-101 338.9 4.0 2.6e-99 332.1 1.3 2.1 2 0 0 2 2 2 2 Cation transport protein Pkinase PF00069.20 EEQ71148.1 - 8.2e-23 80.8 0.0 2.4e-22 79.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ71148.1 - 4.2e-07 29.2 0.3 0.018 14.1 0.0 3.1 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EEQ71148.1 - 0.0026 17.5 0.2 0.014 15.1 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ71148.1 - 0.062 12.3 0.0 0.098 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SRP9-21 PF05486.7 EEQ71149.1 - 0.16 11.7 0.5 0.26 11.0 0.3 1.3 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) Pox_P35 PF03213.9 EEQ71152.1 - 0.049 12.6 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Poxvirus P35 protein DUF390 PF04094.9 EEQ71152.1 - 0.15 10.0 16.9 0.31 9.0 11.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Ycf1 PF05758.7 EEQ71152.1 - 0.17 9.5 11.6 0.24 9.0 8.0 1.2 1 0 0 1 1 1 0 Ycf1 Tim54 PF11711.3 EEQ71152.1 - 0.23 10.0 11.6 0.41 9.1 8.1 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SAPS PF04499.10 EEQ71152.1 - 0.26 9.8 9.7 0.37 9.3 6.7 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Raftlin PF15250.1 EEQ71152.1 - 0.48 8.8 12.3 1 7.7 8.5 1.4 1 0 0 1 1 1 0 Raftlin Spore_coat_CotO PF14153.1 EEQ71152.1 - 0.55 9.6 21.1 1.1 8.6 14.7 1.5 1 0 0 1 1 1 0 Spore coat protein CotO Borrelia_P83 PF05262.6 EEQ71152.1 - 0.8 7.9 23.8 1.3 7.2 16.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3584 PF12128.3 EEQ71152.1 - 2.8 5.1 29.5 4.2 4.5 20.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NARP1 PF12569.3 EEQ71152.1 - 5.1 5.7 22.0 10 4.7 15.2 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CDC45 PF02724.9 EEQ71152.1 - 5.4 4.9 19.3 9.2 4.1 13.4 1.3 1 0 0 1 1 1 0 CDC45-like protein V_ATPase_I PF01496.14 EEQ71152.1 - 5.8 4.6 9.8 7.9 4.1 6.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Dynamin_N PF00350.18 EEQ71154.1 - 2.9e-33 115.0 1.3 4.4e-33 114.4 0.0 2.0 3 0 0 3 3 3 1 Dynamin family Dynamin_M PF01031.15 EEQ71154.1 - 5.8e-18 64.6 0.1 1.2e-16 60.3 0.1 2.3 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 EEQ71154.1 - 0.00038 20.3 0.0 0.0018 18.1 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEQ71154.1 - 0.0063 16.9 0.1 0.029 14.8 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein ApoLp-III PF07464.6 EEQ71154.1 - 0.0064 16.5 0.8 0.018 15.0 0.1 2.0 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) PilJ PF13675.1 EEQ71154.1 - 0.031 14.6 0.4 7 6.9 0.1 3.5 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term AAA_21 PF13304.1 EEQ71154.1 - 0.061 13.2 0.2 0.41 10.5 0.0 2.3 3 0 0 3 3 3 0 AAA domain Syntaxin_2 PF14523.1 EEQ71154.1 - 0.16 12.0 6.7 0.13 12.3 1.4 2.7 2 1 0 2 2 2 0 Syntaxin-like protein AAA_23 PF13476.1 EEQ71154.1 - 0.82 9.9 7.1 66 3.7 4.9 3.2 1 1 0 1 1 1 0 AAA domain APH PF01636.18 EEQ71155.1 - 6.4e-11 42.4 0.1 8e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ71155.1 - 1.1e-05 25.1 0.0 1.5e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EEQ71155.1 - 0.0029 16.7 0.0 0.0039 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EEQ71155.1 - 0.0036 16.6 0.1 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Tenui_PVC2 PF06656.6 EEQ71155.1 - 0.067 10.9 0.0 0.087 10.6 0.0 1.1 1 0 0 1 1 1 0 Tenuivirus PVC2 protein DUF3435 PF11917.3 EEQ71156.1 - 4.5e-121 404.4 6.0 1.3e-120 402.9 3.2 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3435) Phage_integrase PF00589.17 EEQ71156.1 - 0.00017 21.2 0.0 0.00077 19.1 0.0 2.0 2 0 0 2 2 2 1 Phage integrase family Pentaxin PF00354.12 EEQ71157.1 - 0.064 12.6 0.1 0.094 12.1 0.1 1.2 1 0 0 1 1 1 0 Pentaxin family Imm23 PF15593.1 EEQ71157.1 - 0.21 11.8 5.4 0.25 11.5 3.7 1.1 1 0 0 1 1 1 0 Immunity protein 23 Cyclin PF08613.6 EEQ71158.1 - 1.1e-13 51.9 0.0 1.6e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EEQ71158.1 - 0.0071 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain His_Phos_1 PF00300.17 EEQ71159.1 - 8e-32 110.5 0.4 1.7e-31 109.4 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EEQ71159.1 - 4.3e-05 23.0 0.0 7.6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Dor1 PF04124.7 EEQ71160.1 - 1.5e-51 174.9 2.0 2.3e-47 161.1 0.7 3.1 1 1 1 2 2 2 2 Dor1-like family Vps51 PF08700.6 EEQ71160.1 - 0.00048 19.9 0.3 0.0016 18.1 0.2 2.0 1 0 0 1 1 1 1 Vps51/Vps67 EAF PF09816.4 EEQ71161.1 - 2e-24 85.6 0.1 4.9e-24 84.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor DHQ_synthase PF01761.15 EEQ71161.1 - 1.6 7.5 3.9 3 6.7 2.7 1.4 1 0 0 1 1 1 0 3-dehydroquinate synthase Cyclin_N PF00134.18 EEQ71162.1 - 2.1e-15 56.3 0.5 7.1e-15 54.7 0.1 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EEQ71162.1 - 1.7e-07 31.1 0.4 1.5e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF1777 PF08648.7 EEQ71162.1 - 0.00011 22.0 23.6 0.00011 22.0 16.4 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1777) TFIIB PF00382.14 EEQ71162.1 - 0.00077 19.2 3.8 0.31 10.8 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat CDC45 PF02724.9 EEQ71162.1 - 0.63 8.0 6.3 4.1 5.3 3.3 2.2 2 0 0 2 2 2 0 CDC45-like protein Methyltransf_23 PF13489.1 EEQ71164.1 - 1.2e-26 93.4 0.0 1.7e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ71164.1 - 1.7e-05 25.3 0.0 4e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ71164.1 - 2.7e-05 24.5 0.0 0.0049 17.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ71164.1 - 6.4e-05 23.2 0.0 0.00013 22.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ71164.1 - 0.00016 21.2 0.0 0.02 14.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ71164.1 - 0.00067 20.0 0.0 0.13 12.7 0.0 3.0 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ71164.1 - 0.11 11.6 0.0 0.26 10.3 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Pex14_N PF04695.8 EEQ71164.1 - 0.38 10.7 2.7 0.34 10.9 0.2 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DAO PF01266.19 EEQ71165.1 - 1.9e-53 181.6 0.5 2.3e-53 181.3 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEQ71165.1 - 7e-08 32.5 0.0 0.002 18.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEQ71165.1 - 7.3e-06 25.0 0.0 0.00068 18.6 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EEQ71165.1 - 1.7e-05 24.6 0.6 0.078 12.7 0.0 2.9 3 1 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EEQ71165.1 - 0.0002 21.3 0.1 0.0012 18.8 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EEQ71165.1 - 0.00021 20.3 0.1 0.01 14.7 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EEQ71165.1 - 0.00043 19.0 0.1 0.16 10.5 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.22 EEQ71165.1 - 0.0014 19.0 0.3 0.0056 17.0 0.0 2.2 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEQ71165.1 - 0.011 15.8 0.2 4.9 7.1 0.0 2.6 1 1 2 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEQ71165.1 - 0.026 13.3 0.4 0.83 8.4 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 EEQ71165.1 - 0.056 12.4 0.1 1.3 8.0 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.13 EEQ71165.1 - 0.056 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain TBP PF00352.16 EEQ71166.1 - 5e-70 230.8 0.1 4.7e-35 118.8 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EEQ71166.1 - 0.00012 22.0 0.0 0.43 10.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF963 PF06131.6 EEQ71168.1 - 0.77 9.0 2.9 3.8 6.8 0.1 2.7 3 0 0 3 3 3 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) ETF_QO PF05187.8 EEQ71169.1 - 6.8e-47 158.0 0.1 1.1e-46 157.3 0.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EEQ71169.1 - 2.3e-09 36.6 0.0 3.8e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEQ71169.1 - 8.1e-06 25.7 0.0 2.1e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EEQ71169.1 - 1.7e-05 23.8 0.1 0.0033 16.3 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EEQ71169.1 - 4e-05 22.8 0.0 7.3e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEQ71169.1 - 0.00011 22.2 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEQ71169.1 - 0.00017 20.1 0.4 0.00027 19.5 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EEQ71169.1 - 0.00023 21.2 0.0 0.00042 20.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEQ71169.1 - 0.00068 18.7 0.0 0.0032 16.6 0.1 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 EEQ71169.1 - 0.0014 18.9 0.0 2.4 8.6 0.2 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EEQ71169.1 - 0.0022 17.1 0.1 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Fer4_7 PF12838.2 EEQ71169.1 - 0.0071 16.7 0.7 0.025 14.9 0.5 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Trp_halogenase PF04820.9 EEQ71169.1 - 0.009 14.6 0.1 0.083 11.5 0.2 2.0 1 1 1 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.1 EEQ71169.1 - 0.018 14.7 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 EEQ71169.1 - 0.039 12.8 0.2 0.069 11.9 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EEQ71169.1 - 0.065 12.1 0.2 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein RRM_1 PF00076.17 EEQ71170.1 - 8.4e-12 44.5 0.0 3.6e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ71170.1 - 8.1e-09 35.2 0.0 0.00034 20.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ71170.1 - 5.2e-06 26.3 0.0 0.0011 18.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pro-rich PF15240.1 EEQ71170.1 - 0.11 12.5 18.1 0.17 11.9 12.5 1.2 1 0 0 1 1 1 0 Proline-rich FolB PF02152.13 EEQ71171.1 - 3.8e-22 78.5 0.0 1e-19 70.7 0.0 2.5 2 1 0 2 2 2 2 Dihydroneopterin aldolase Pkinase PF00069.20 EEQ71172.1 - 6.6e-64 215.5 0.0 8.3e-64 215.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ71172.1 - 7.9e-29 100.5 0.0 1.1e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ71172.1 - 0.0019 17.2 0.0 0.0041 16.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EEQ71172.1 - 0.019 14.6 1.3 1.1 8.9 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ndc80_HEC PF03801.8 EEQ71174.1 - 1.7e-63 212.8 0.1 5.1e-63 211.2 0.1 1.9 1 0 0 1 1 1 1 HEC/Ndc80p family Cast PF10174.4 EEQ71174.1 - 0.024 12.7 42.6 0.033 12.2 12.6 2.1 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone TPR_MLP1_2 PF07926.7 EEQ71174.1 - 0.38 10.4 41.9 0.05 13.3 8.6 3.7 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Filament PF00038.16 EEQ71174.1 - 0.78 9.1 45.6 2.4 7.5 9.5 2.8 2 1 0 2 2 2 0 Intermediate filament protein IncA PF04156.9 EEQ71174.1 - 6.2 6.3 48.2 0.37 10.3 15.4 4.1 2 2 1 3 3 3 0 IncA protein GAS PF13851.1 EEQ71174.1 - 8.1 5.5 50.4 0.67 9.1 16.9 3.5 2 2 1 3 3 3 0 Growth-arrest specific micro-tubule binding Pex14_N PF04695.8 EEQ71175.1 - 5e-43 146.4 0.0 5e-43 146.4 0.0 3.0 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3584 PF12128.3 EEQ71175.1 - 0.075 10.3 2.1 0.1 9.9 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GRIM-19 PF06212.7 EEQ71175.1 - 0.12 12.0 0.2 0.28 10.8 0.1 1.6 1 0 0 1 1 1 0 GRIM-19 protein Sipho_Gp157 PF05565.6 EEQ71175.1 - 0.25 10.9 2.7 0.85 9.1 1.9 1.8 1 1 0 1 1 1 0 Siphovirus Gp157 Baculo_PEP_C PF04513.7 EEQ71175.1 - 0.29 10.9 1.9 21 4.9 1.2 2.3 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EEQ71175.1 - 0.5 10.1 2.7 1.5 8.6 1.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.9 EEQ71175.1 - 0.54 9.8 4.6 0.56 9.7 1.5 2.1 2 1 0 2 2 2 0 IncA protein DUF4164 PF13747.1 EEQ71175.1 - 0.85 9.8 10.3 0.18 11.9 3.3 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) zf-C4H2 PF10146.4 EEQ71175.1 - 3.3 7.6 9.1 0.42 10.6 3.0 2.0 2 1 0 2 2 2 0 Zinc finger-containing protein ABC_tran PF00005.22 EEQ71177.1 - 1.5e-37 128.9 0.1 3.7e-37 127.6 0.1 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EEQ71177.1 - 1.2e-12 47.8 8.5 1.2e-12 47.8 5.9 2.1 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_21 PF13304.1 EEQ71177.1 - 7.2e-05 22.8 0.0 0.0044 17.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain YrhK PF14145.1 EEQ71177.1 - 0.00075 19.1 0.8 0.015 14.9 0.6 2.6 2 0 0 2 2 2 1 YrhK-like protein DUF258 PF03193.11 EEQ71177.1 - 0.0038 16.4 0.1 0.0075 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EEQ71177.1 - 0.0056 16.1 0.1 0.018 14.5 0.1 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EEQ71177.1 - 0.0095 15.8 0.1 0.068 13.0 0.1 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EEQ71177.1 - 0.022 14.8 0.1 0.074 13.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EEQ71177.1 - 0.027 14.8 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.15 EEQ71177.1 - 0.037 12.7 0.0 0.037 12.7 0.0 2.0 3 0 0 3 3 3 0 G-protein alpha subunit Zeta_toxin PF06414.7 EEQ71177.1 - 0.046 12.8 0.3 0.1 11.6 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.9 EEQ71177.1 - 0.065 12.9 0.2 0.38 10.4 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EEQ71177.1 - 0.098 12.0 0.0 0.46 9.8 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 EEQ71177.1 - 0.13 13.0 0.0 0.4 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain PAM2 PF07145.10 EEQ71177.1 - 0.15 11.6 0.4 0.34 10.4 0.3 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region TTL PF03133.10 EEQ71179.1 - 1.6e-55 188.1 0.0 2.5e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 EEQ71179.1 - 8e-42 142.7 0.0 1.2e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.1 EEQ71179.1 - 0.00036 19.4 0.0 0.0011 17.7 0.0 1.8 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 EEQ71179.1 - 0.013 15.2 0.0 2.3 7.8 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain Glyco_trans_4_4 PF13579.1 EEQ71179.1 - 0.071 13.2 0.0 3.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Dala_Dala_lig_C PF07478.8 EEQ71179.1 - 0.13 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DUF3414 PF11894.3 EEQ71179.1 - 0.29 7.9 0.1 0.4 7.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3414) Seipin PF06775.9 EEQ71180.1 - 1.9e-66 223.3 0.3 2.6e-66 222.9 0.2 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Aph-1 PF06105.7 EEQ71180.1 - 4.2 6.5 9.0 0.25 10.5 2.6 1.5 2 0 0 2 2 2 0 Aph-1 protein Not1 PF04054.10 EEQ71181.1 - 2.5e-142 474.2 1.7 4.2e-142 473.4 0.2 2.2 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EEQ71181.1 - 2.5e-51 173.2 2.7 8.4e-51 171.5 1.9 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) FCH PF00611.18 EEQ71182.1 - 4.4e-20 71.6 0.0 4.4e-20 71.6 0.0 3.5 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EEQ71182.1 - 2.5e-12 45.9 0.1 5.5e-12 44.8 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EEQ71182.1 - 5.4e-12 45.0 0.0 2.8e-11 42.7 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 EEQ71182.1 - 1.2e-09 37.5 0.0 2.5e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Spore_coat_CotO PF14153.1 EEQ71182.1 - 0.0033 16.8 15.2 0.0033 16.8 10.6 3.2 3 0 0 3 3 3 1 Spore coat protein CotO AAA_23 PF13476.1 EEQ71182.1 - 0.0098 16.2 12.6 0.0098 16.2 8.7 2.3 2 0 0 2 2 2 1 AAA domain zf-DHHC PF01529.15 EEQ71182.1 - 1.5 8.2 5.0 3.7 6.9 3.5 1.7 1 0 0 1 1 1 0 DHHC palmitoyltransferase LMBR1 PF04791.11 EEQ71182.1 - 3.2 6.2 3.0 5.4 5.4 2.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Tic20 PF09685.5 EEQ71183.1 - 7.2e-08 32.3 1.6 9.3e-08 32.0 1.1 1.2 1 0 0 1 1 1 1 Tic20-like protein DASH_Duo1 PF08651.5 EEQ71184.1 - 1.3e-28 98.4 2.4 1.3e-28 98.4 1.7 2.1 2 0 0 2 2 2 1 DASH complex subunit Duo1 DUF745 PF05335.8 EEQ71184.1 - 0.0015 18.0 7.7 0.0022 17.5 5.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF745) SPX PF03105.14 EEQ71184.1 - 0.0088 15.8 0.0 0.022 14.5 0.0 1.5 1 1 0 1 1 1 1 SPX domain Macoilin PF09726.4 EEQ71184.1 - 0.081 11.1 10.4 0.11 10.7 7.2 1.2 1 0 0 1 1 1 0 Transmembrane protein LMBR1 PF04791.11 EEQ71184.1 - 1.8 7.0 3.7 2 6.9 2.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-primase PF09329.6 EEQ71186.1 - 1.7e-19 69.1 0.4 3.1e-19 68.3 0.3 1.5 1 0 0 1 1 1 1 Primase zinc finger RNase_H2-Ydr279 PF09468.5 EEQ71187.1 - 1.6e-80 270.5 2.3 2.2e-80 270.1 1.6 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DUF3435 PF11917.3 EEQ71189.1 - 4e-92 309.1 12.4 2e-90 303.4 8.6 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) Fungal_trans PF04082.13 EEQ71193.1 - 2.2e-15 56.2 0.0 5.8e-15 54.8 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ71193.1 - 5.6e-06 26.1 8.1 1e-05 25.3 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Neil1-DNA_bind PF09292.5 EEQ71193.1 - 0.18 11.6 1.3 0.33 10.7 0.1 2.1 2 0 0 2 2 2 0 Endonuclease VIII-like 1, DNA bind adh_short PF00106.20 EEQ71194.1 - 4.3e-26 91.8 0.1 6e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ71194.1 - 1e-13 51.6 0.0 1.2e-13 51.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ71194.1 - 4.2e-11 42.8 0.0 6.1e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEQ71194.1 - 0.0094 15.4 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EEQ71194.1 - 0.018 14.7 1.9 0.022 14.5 0.3 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ACT_7 PF13840.1 EEQ71194.1 - 0.072 12.6 0.0 0.23 11.0 0.0 1.8 1 0 0 1 1 1 0 ACT domain ADH_N PF08240.7 EEQ71195.1 - 3.6e-27 94.2 0.1 9.6e-27 92.8 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ71195.1 - 3.2e-11 42.8 0.0 2.6e-10 39.9 0.0 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ApbA PF02558.11 EEQ71195.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 EEQ71195.1 - 0.062 12.2 0.0 0.098 11.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase 2-Hacid_dh_C PF02826.14 EEQ71196.1 - 1.1e-51 174.4 0.0 1.6e-51 173.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEQ71196.1 - 2.8e-19 68.9 0.0 3.8e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 EEQ71196.1 - 0.00077 19.3 0.1 0.0017 18.1 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.10 EEQ71196.1 - 0.0014 18.4 0.5 0.013 15.3 0.1 2.5 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EEQ71196.1 - 0.024 14.0 0.3 0.046 13.1 0.0 1.5 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain XdhC_C PF13478.1 EEQ71196.1 - 0.036 14.3 0.0 0.077 13.2 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain Ribosomal_L22 PF00237.14 EEQ71197.1 - 5.4e-35 119.5 0.0 8e-35 118.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Glyco_hydro_20 PF00728.17 EEQ71199.1 - 4e-31 108.4 2.9 2.5e-30 105.8 2.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.10 EEQ71199.1 - 2.7e-11 44.0 0.0 6.7e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Epimerase PF01370.16 EEQ71200.1 - 1.3e-10 41.0 0.0 2e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EEQ71200.1 - 3.3e-07 29.4 0.0 0.00074 18.5 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EEQ71200.1 - 6.5e-07 28.3 0.0 1.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EEQ71200.1 - 5.7e-05 23.1 0.1 0.0003 20.8 0.1 2.1 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EEQ71200.1 - 0.00077 18.7 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family UBA_4 PF14555.1 EEQ71201.1 - 2.2e-11 43.1 0.2 4.5e-11 42.0 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EEQ71201.1 - 5.2e-09 36.0 0.0 1.2e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 UBX domain Pkinase PF00069.20 EEQ71202.1 - 4.5e-07 29.2 0.0 8e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LSM PF01423.17 EEQ71203.1 - 9.5e-19 66.7 0.2 1.3e-18 66.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain Suf PF05843.9 EEQ71203.1 - 0.078 12.7 0.0 0.087 12.5 0.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) E_Pc_C PF06752.7 EEQ71203.1 - 2.8 7.3 7.0 3.3 7.1 4.8 1.1 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus DUF4175 PF13779.1 EEQ71203.1 - 3.4 5.2 10.4 3.5 5.1 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) dsDNA_bind PF01984.15 EEQ71203.1 - 5.7 6.9 8.2 10 6.1 5.7 1.3 1 0 0 1 1 1 0 Double-stranded DNA-binding domain AAA PF00004.24 EEQ71204.1 - 1.8e-18 66.9 0.0 3.6e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEQ71204.1 - 9.3e-05 23.2 0.8 0.0022 18.8 0.0 3.3 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.9 EEQ71204.1 - 0.00014 21.6 0.0 0.00073 19.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EEQ71204.1 - 0.00018 21.8 0.3 0.0011 19.3 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EEQ71204.1 - 0.00027 20.9 0.0 0.00073 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EEQ71204.1 - 0.00035 20.2 0.0 0.00073 19.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EEQ71204.1 - 0.0015 18.6 0.1 0.018 15.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EEQ71204.1 - 0.0019 17.6 0.0 0.0079 15.6 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EEQ71204.1 - 0.019 14.1 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EEQ71204.1 - 0.02 14.7 0.0 0.17 11.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EEQ71204.1 - 0.021 14.7 0.0 0.069 13.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 EEQ71204.1 - 0.023 14.1 0.2 0.39 10.1 0.1 2.5 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) FNIP_N PF14636.1 EEQ71204.1 - 0.027 14.9 0.6 0.047 14.1 0.0 1.7 2 0 0 2 2 1 0 Folliculin-interacting protein N-terminus T2SE PF00437.15 EEQ71204.1 - 0.047 12.6 0.0 0.095 11.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 EEQ71204.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 EEQ71204.1 - 0.11 12.4 0.0 0.38 10.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.21 EEQ71204.1 - 0.13 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain efThoc1 PF11957.3 EEQ71209.1 - 0.0047 15.4 10.3 0.0055 15.2 7.2 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor DUF3007 PF11460.3 EEQ71209.1 - 0.27 11.3 3.2 1.2 9.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) CRT10 PF08728.5 EEQ71209.1 - 0.64 7.9 8.6 0.73 7.7 6.0 1.0 1 0 0 1 1 1 0 CRT10 F-box PF00646.28 EEQ71212.1 - 1.4e-07 30.9 0.2 4.2e-07 29.4 0.2 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EEQ71212.1 - 7.4e-06 25.6 0.1 7.4e-06 25.6 0.1 2.6 3 0 0 3 3 3 1 F-box-like F-box-like_2 PF13013.1 EEQ71212.1 - 0.37 10.5 4.0 0.88 9.3 2.7 2.0 1 1 0 1 1 1 0 F-box-like domain zf-C3HC4 PF00097.20 EEQ71214.1 - 0.012 15.2 5.3 0.036 13.7 3.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ71214.1 - 0.022 14.8 5.2 0.076 13.0 3.6 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ71214.1 - 0.027 14.2 6.0 0.031 13.9 3.1 1.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 EEQ71214.1 - 0.13 12.0 2.3 0.22 11.2 0.7 2.1 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EEQ71214.1 - 0.3 11.0 5.2 1.3 8.9 3.6 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EEQ71214.1 - 2.2 8.1 9.5 0.43 10.4 3.6 2.1 1 1 1 2 2 2 0 Ring finger domain DUF3723 PF12520.3 EEQ71218.1 - 1.7e-11 43.3 0.0 1.8e-08 33.3 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) HalX PF08663.5 EEQ71219.1 - 0.04 13.8 0.3 0.084 12.8 0.2 1.4 1 0 0 1 1 1 0 HalX domain Myb_DNA-bind_5 PF13873.1 EEQ71220.1 - 2.4e-05 24.1 0.3 0.00015 21.5 0.3 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF1932 PF09130.6 EEQ71220.1 - 0.041 13.6 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) gp12-short_mid PF09089.5 EEQ71220.1 - 0.08 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Phage short tail fibre protein gp12, middle domain BCL9 PF11502.3 EEQ71222.1 - 0.14 11.7 0.3 0.27 10.7 0.2 1.4 1 0 0 1 1 1 0 B-cell lymphoma 9 protein DnaJ PF00226.26 EEQ71225.1 - 5.4e-15 54.8 0.1 1.5e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain PLAT PF01477.18 EEQ71226.1 - 0.14 12.5 0.1 3 8.2 0.1 2.5 1 1 0 1 1 1 0 PLAT/LH2 domain RasGEF PF00617.14 EEQ71230.1 - 0.0036 17.0 0.0 0.012 15.3 0.0 1.9 1 1 0 1 1 1 1 RasGEF domain Hce2 PF14856.1 EEQ71231.1 - 0.055 13.3 0.3 1.5 8.8 0.0 2.9 3 0 0 3 3 3 0 Pathogen effector; putative necrosis-inducing factor SUZ PF12752.2 EEQ71232.1 - 1.9 9.0 5.7 1.7 9.2 2.6 1.9 2 0 0 2 2 2 0 SUZ domain AAA PF00004.24 EEQ71233.1 - 0.0019 18.3 0.0 0.0032 17.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2007 PF09413.5 EEQ71234.1 - 0.018 14.8 0.0 0.076 12.8 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2007) NTP_transf_5 PF14907.1 EEQ71234.1 - 0.023 14.0 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase Metallophos_2 PF12850.2 EEQ71235.1 - 2.1e-06 27.6 0.0 3.7e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EEQ71235.1 - 0.0014 18.0 2.2 0.012 15.0 1.6 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1814 PF08843.6 EEQ71236.1 - 0.00012 21.9 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) TUSC2 PF15000.1 EEQ71237.1 - 0.083 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Tumour suppressor candidate 2 Pkinase PF00069.20 EEQ71239.1 - 0.0095 15.1 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ71239.1 - 0.021 13.8 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF4105 PF13387.1 EEQ71239.1 - 0.051 12.7 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) DUF3723 PF12520.3 EEQ71240.1 - 0.049 12.1 0.0 0.35 9.2 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3723) Ytp1 PF10355.4 EEQ71241.1 - 0.047 12.8 3.7 0.059 12.5 2.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (Ytp1) DUF4134 PF13572.1 EEQ71241.1 - 0.08 13.0 0.2 0.22 11.6 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4134) UTP15_C PF09384.5 EEQ71241.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 UTP15 C terminal BTB PF00651.26 EEQ71245.1 - 6.7e-13 48.6 0.0 1.1e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain NYD-SP28 PF14772.1 EEQ71246.1 - 0.062 13.3 0.3 0.46 10.5 0.0 2.1 2 0 0 2 2 2 0 Sperm tail SPATA24 PF15175.1 EEQ71247.1 - 0.073 12.7 0.4 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Spermatogenesis-associated protein 24 Dioxygenase_C PF00775.16 EEQ71248.1 - 6.6e-49 165.6 0.0 9e-49 165.2 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EEQ71248.1 - 4e-15 55.5 0.0 1e-14 54.2 0.0 1.7 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EEQ71248.1 - 0.018 15.0 0.0 0.056 13.5 0.0 1.8 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Vps39_2 PF10367.4 EEQ71249.1 - 9.5e-05 22.5 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 EEQ71249.1 - 0.0012 18.8 0.1 0.08 12.9 0.0 3.0 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 CASP_C PF08172.7 EEQ71250.1 - 1.1e-83 280.1 2.3 1.1e-83 280.1 1.6 3.7 3 0 0 3 3 3 1 CASP C terminal DUF2644 PF10841.3 EEQ71250.1 - 0.16 12.0 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2644) NAD_binding_1 PF00175.16 EEQ71250.1 - 1 9.9 3.2 2 9.0 0.0 2.8 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain SlyX PF04102.7 EEQ71250.1 - 2.4 8.6 21.9 5.8 7.3 0.6 5.3 4 1 0 4 4 4 0 SlyX DUF3455 PF11937.3 EEQ71251.1 - 4.4e-39 134.2 0.0 5.9e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.3 EEQ71251.1 - 0.0024 17.7 0.1 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2990) Mannosyl_trans3 PF11051.3 EEQ71254.1 - 3.7e-71 239.6 0.0 8.8e-71 238.4 0.0 1.6 1 1 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 EEQ71254.1 - 0.11 11.7 0.2 0.22 10.7 0.1 1.4 1 1 0 1 1 1 0 Glycosyl transferase family 8 F-box-like PF12937.2 EEQ71255.1 - 0.0078 15.9 0.3 0.045 13.4 0.0 2.4 2 0 0 2 2 2 1 F-box-like Fibrillarin PF01269.12 EEQ71256.1 - 9.4e-107 355.1 0.0 1.1e-106 354.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EEQ71256.1 - 8.9e-06 25.3 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EEQ71256.1 - 0.028 14.0 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EEQ71256.1 - 0.036 13.5 0.1 0.052 13.0 0.0 1.3 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Epimerase PF01370.16 EEQ71257.1 - 7.5e-21 74.6 0.0 1e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEQ71257.1 - 2.8e-12 45.9 0.0 3.8e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EEQ71257.1 - 1.9e-07 30.2 0.6 8.3e-06 24.9 0.4 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EEQ71257.1 - 9.5e-07 28.8 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EEQ71257.1 - 3.7e-05 23.8 0.0 5.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EEQ71257.1 - 0.00075 18.4 0.0 0.002 17.1 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 EEQ71257.1 - 0.02 14.5 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 KR domain Saccharop_dh PF03435.13 EEQ71257.1 - 0.037 13.0 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EEQ71257.1 - 0.04 12.8 0.0 0.32 9.8 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 EEQ71257.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Ank_2 PF12796.2 EEQ71258.1 - 3.8e-05 23.9 0.0 5.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EEQ71258.1 - 0.00016 21.5 0.0 0.36 11.1 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EEQ71258.1 - 0.0061 16.7 0.0 4.6 7.6 0.0 2.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 EEQ71258.1 - 0.013 15.3 0.1 8.1 6.4 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeat Ank_4 PF13637.1 EEQ71258.1 - 0.055 14.0 0.2 2.4 8.8 0.0 2.3 1 1 0 2 2 2 0 Ankyrin repeats (many copies) Peptidase_M16 PF00675.15 EEQ71260.1 - 2.8e-56 189.4 0.2 8.4e-56 187.8 0.1 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EEQ71260.1 - 3.5e-38 131.1 0.0 1.3e-36 126.0 0.0 2.5 3 0 0 3 3 3 1 Peptidase M16 inactive domain ADH_zinc_N PF00107.21 EEQ71261.1 - 2.6e-22 78.7 0.1 4.2e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEQ71261.1 - 3.6e-11 44.0 0.0 6.1e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PGM_PMM_II PF02879.11 EEQ71261.1 - 0.13 12.6 0.1 0.38 11.1 0.0 2.0 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II CybS PF05328.7 EEQ71262.1 - 1.6e-54 183.1 0.0 2.4e-54 182.5 0.0 1.3 1 0 0 1 1 1 1 CybS Maf PF02545.9 EEQ71263.1 - 7.7e-44 149.1 0.0 1e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein HLH PF00010.21 EEQ71264.1 - 1.3e-07 31.1 0.0 2.5e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Umbravirus_LDM PF04817.7 EEQ71264.1 - 0.0038 16.4 0.8 0.0041 16.2 0.5 1.1 1 0 0 1 1 1 1 Umbravirus long distance movement (LDM) family Glycoprotein_G PF00802.14 EEQ71264.1 - 0.005 16.0 1.2 0.0061 15.7 0.9 1.1 1 0 0 1 1 1 1 Pneumovirus attachment glycoprotein G DUF2559 PF10832.3 EEQ71264.1 - 0.073 12.8 0.3 0.14 11.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2559) Hamartin PF04388.7 EEQ71264.1 - 0.27 9.8 6.2 0.29 9.7 4.3 1.0 1 0 0 1 1 1 0 Hamartin protein DUF605 PF04652.11 EEQ71264.1 - 0.39 10.0 8.3 0.41 9.9 5.8 1.0 1 0 0 1 1 1 0 Vta1 like X PF00739.14 EEQ71264.1 - 0.45 10.4 4.5 0.6 10.0 3.1 1.2 1 0 0 1 1 1 0 Trans-activation protein X Med3 PF11593.3 EEQ71264.1 - 6.1 5.9 11.1 8 5.5 7.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal GFA PF04828.9 EEQ71265.1 - 0.0028 17.5 0.0 0.0058 16.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EEQ71265.1 - 0.086 12.0 0.5 0.19 10.9 0.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 EEQ71265.1 - 1.6 8.3 5.3 0.52 9.8 1.3 1.9 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DUF3328 PF11807.3 EEQ71268.1 - 2.7e-48 164.5 0.5 3.6e-48 164.1 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) WI12 PF07107.6 EEQ71268.1 - 0.12 12.3 0.1 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Wound-induced protein WI12 Glyco_hydro_47 PF01532.15 EEQ71269.1 - 3.7e-118 395.0 0.0 1.8e-97 326.8 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 Ank_2 PF12796.2 EEQ71269.1 - 0.16 12.3 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) GST_C PF00043.20 EEQ71271.1 - 4.9e-15 55.3 0.0 9.1e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEQ71271.1 - 7.9e-10 38.4 0.0 1.4e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEQ71271.1 - 3.5e-07 30.6 0.0 6.6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EEQ71271.1 - 8.2e-07 29.1 0.1 2.3e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EEQ71271.1 - 5.6e-06 26.4 0.0 1.5e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEQ71271.1 - 3.5e-05 23.7 0.1 0.0001 22.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Histidinol_dh PF00815.15 EEQ71272.1 - 3.1e-179 595.9 5.3 5.2e-179 595.1 3.7 1.4 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 EEQ71272.1 - 9.9e-27 92.3 0.2 2.2e-26 91.2 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EEQ71272.1 - 3.5e-12 46.4 0.2 3.5e-12 46.4 0.1 2.3 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase PrpR_N PF06506.6 EEQ71272.1 - 0.017 14.5 2.0 0.28 10.5 0.0 3.7 4 0 0 4 4 4 0 Propionate catabolism activator adh_short PF00106.20 EEQ71273.1 - 8.4e-21 74.5 0.4 1.3e-20 73.9 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ71273.1 - 2.1e-09 37.2 0.1 8.4e-09 35.3 0.1 1.9 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEQ71273.1 - 1e-07 32.0 0.0 1.4e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EEQ71273.1 - 0.017 14.8 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Utp11 PF03998.8 EEQ71274.1 - 1.8e-55 188.4 26.0 2.3e-55 188.0 18.1 1.1 1 0 0 1 1 1 1 Utp11 protein Cmc1 PF08583.5 EEQ71275.1 - 3.2e-17 62.0 2.3 3.2e-17 62.0 1.6 1.9 2 1 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EEQ71275.1 - 0.15 12.0 0.7 0.81 9.6 0.5 2.0 1 1 0 1 1 1 0 CHCH domain Phage-scaffold PF09306.5 EEQ71275.1 - 2 7.5 7.3 2.7 7.0 5.1 1.2 1 0 0 1 1 1 0 Bacteriophage, scaffolding protein TFIID-31kDa PF02291.10 EEQ71276.1 - 2.9e-28 98.2 0.0 4.9e-14 52.2 0.0 3.1 3 0 0 3 3 3 3 Transcription initiation factor IID, 31kD subunit LNS2 PF08235.8 EEQ71277.1 - 4e-71 237.6 0.0 7.1e-71 236.8 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EEQ71277.1 - 1.4e-40 137.4 0.0 3.6e-40 136.0 0.0 1.7 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 EEQ71277.1 - 0.017 14.4 0.0 0.49 9.7 0.0 2.5 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) AF1Q PF15017.1 EEQ71277.1 - 0.16 11.8 10.0 0.093 12.6 0.3 2.7 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator fn3 PF00041.16 EEQ71278.1 - 6.5e-08 32.5 0.0 2.1e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain Myosin_tail_1 PF01576.14 EEQ71278.1 - 0.0038 15.0 43.1 0.0056 14.4 29.9 1.1 1 0 0 1 1 1 1 Myosin tail GAS PF13851.1 EEQ71278.1 - 0.93 8.6 41.4 0.34 10.0 8.9 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 EEQ71278.1 - 1.2 8.1 39.7 1.3 7.9 9.5 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 EEQ71278.1 - 6.2 6.3 53.4 0.064 12.8 17.4 3.1 2 1 1 3 3 3 0 IncA protein Thg1C PF14413.1 EEQ71279.1 - 7.4e-47 158.0 2.5 6.9e-41 138.7 0.2 2.2 2 0 0 2 2 2 2 Thg1 C terminal domain Thg1 PF04446.7 EEQ71279.1 - 1.2e-36 125.3 0.0 2e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase DUF2214 PF09980.4 EEQ71279.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2214) DUF1218 PF06749.7 EEQ71279.1 - 0.12 12.7 0.1 6.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Totivirus_coat PF05518.6 EEQ71280.1 - 4.7 4.9 6.4 6.1 4.5 4.4 1.1 1 0 0 1 1 1 0 Totivirus coat protein Pkinase PF00069.20 EEQ71281.1 - 1.6e-06 27.4 0.0 2.5e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain FTA2 PF13095.1 EEQ71281.1 - 3.6e-05 23.4 0.0 5.3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.18 EEQ71281.1 - 0.017 14.9 0.4 0.07 12.8 0.3 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EEQ71281.1 - 0.022 13.5 0.0 0.031 13.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Hexokinase_1 PF00349.16 EEQ71284.1 - 5.9e-30 104.1 0.0 1.9e-28 99.2 0.0 2.7 1 1 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EEQ71284.1 - 2.1e-29 102.4 0.0 5.4e-24 84.7 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Fe_dep_repr_C PF02742.10 EEQ71284.1 - 0.11 12.1 0.0 0.65 9.7 0.0 2.2 2 1 1 3 3 3 0 Iron dependent repressor, metal binding and dimerisation domain MFS_1 PF07690.11 EEQ71285.1 - 3e-07 29.4 19.0 1.6e-05 23.7 4.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ71285.1 - 6.7e-05 21.6 1.6 0.026 13.0 0.3 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter TFIIA_gamma_C PF02751.9 EEQ71287.1 - 1.9e-27 94.8 2.1 2.6e-27 94.3 1.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 EEQ71287.1 - 2.1e-26 91.2 0.2 3e-26 90.7 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Kinesin-relat_1 PF12711.2 EEQ71289.1 - 0.033 14.5 0.2 0.034 14.5 0.1 1.2 1 0 0 1 1 1 0 Kinesin motor Aldedh PF00171.17 EEQ71290.1 - 3.5e-131 437.7 0.0 3.9e-131 437.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EEQ71290.1 - 4.8e-07 28.8 0.0 1.1e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EEQ71290.1 - 0.0065 15.7 0.1 0.083 12.1 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Methyltransf_33 PF10017.4 EEQ71293.1 - 1.5e-31 108.9 0.0 1.9e-30 105.3 0.0 2.2 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EEQ71293.1 - 4.1e-19 68.9 2.3 1.5e-10 40.9 0.1 2.3 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EEQ71293.1 - 9.5e-10 38.9 1.4 3.8e-09 36.9 0.3 2.4 2 0 0 2 2 2 1 DinB superfamily Methyltransf_25 PF13649.1 EEQ71293.1 - 0.00032 20.9 0.0 0.0019 18.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain DUF92 PF01940.11 EEQ71294.1 - 4.7e-63 212.3 1.4 6.3e-63 211.9 1.0 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Radical_SAM PF04055.16 EEQ71295.1 - 4.9e-10 39.8 0.0 9.1e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EEQ71295.1 - 9.2e-06 25.8 0.0 1.7e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EEQ71295.1 - 0.0023 17.9 0.2 0.0052 16.8 0.2 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain 4HBT PF03061.17 EEQ71297.1 - 9.5e-09 35.2 0.0 1.1e-07 31.8 0.0 2.1 2 0 0 2 2 2 1 Thioesterase superfamily RNA_pol PF00940.14 EEQ71298.1 - 2.3e-157 523.6 0.0 4.4e-157 522.7 0.0 1.5 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EEQ71298.1 - 1.5e-77 260.9 0.1 2.5e-77 260.2 0.1 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Sin_N PF04801.8 EEQ71299.1 - 1.3e-26 93.4 0.2 4.2e-15 55.5 0.0 2.0 2 0 0 2 2 2 2 Sin-like protein conserved region Rho_RNA_bind PF07497.7 EEQ71299.1 - 0.023 14.3 0.1 0.099 12.2 0.0 1.9 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain NIR_SIR PF01077.17 EEQ71300.1 - 8.3e-52 174.6 0.0 2.1e-45 153.8 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EEQ71300.1 - 1.2e-30 104.9 0.0 3.9e-15 55.2 0.0 2.9 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EEQ71300.1 - 9.4e-27 93.7 0.0 1.8e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 EEQ71300.1 - 4.5e-07 29.5 0.0 1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Methyltrans_SAM PF10672.4 EEQ71300.1 - 0.14 10.9 0.0 0.69 8.7 0.0 2.0 2 0 0 2 2 2 0 S-adenosylmethionine-dependent methyltransferase Kei1 PF08552.6 EEQ71301.1 - 4.3e-52 176.5 3.0 4.3e-52 176.5 2.1 2.0 2 0 0 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 SPC12 PF06645.8 EEQ71301.1 - 1.3 8.8 5.0 0.31 10.8 0.4 2.2 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Ras PF00071.17 EEQ71302.1 - 3.8e-59 198.7 0.2 4.8e-59 198.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ71302.1 - 1.4e-20 73.9 0.0 2.2e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ71302.1 - 1.3e-17 63.5 0.2 1.7e-17 63.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEQ71302.1 - 5e-07 29.3 0.0 2.3e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EEQ71302.1 - 1.4e-05 24.3 0.2 1.8e-05 24.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEQ71302.1 - 1.5e-05 24.9 0.0 2.4e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EEQ71302.1 - 5e-05 22.5 0.0 8.8e-05 21.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EEQ71302.1 - 0.03 14.1 0.1 3 7.6 0.0 2.5 2 1 0 2 2 2 0 Dynamin family AAA_14 PF13173.1 EEQ71302.1 - 0.079 12.8 0.2 0.15 11.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EEQ71302.1 - 0.13 12.4 0.0 1.3 9.1 0.0 2.4 1 1 0 1 1 1 0 AAA domain ATP-synt_C PF00137.16 EEQ71303.1 - 6.7e-29 99.5 26.4 9.5e-18 63.8 6.8 2.3 2 0 0 2 2 2 2 ATP synthase subunit C MoCF_biosynth PF00994.19 EEQ71304.1 - 6.6e-47 158.5 0.0 3.6e-23 81.5 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 EEQ71304.1 - 7.9e-34 116.3 2.7 1.4e-33 115.5 1.9 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 EEQ71304.1 - 2.7e-16 59.2 0.0 6.6e-16 58.0 0.0 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) DDHD PF02862.12 EEQ71305.1 - 1e-44 153.0 2.5 6.1e-44 150.5 0.0 3.4 4 1 0 4 4 4 1 DDHD domain Abhydrolase_5 PF12695.2 EEQ71305.1 - 0.013 15.2 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2305 PF10230.4 EEQ71305.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EEQ71305.1 - 0.018 14.9 0.0 0.048 13.5 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family FAD_binding_3 PF01494.14 EEQ71307.1 - 1.6e-70 237.9 0.0 2e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EEQ71307.1 - 4.7e-34 117.4 0.0 7.7e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 EEQ71307.1 - 0.0075 16.6 0.0 0.026 14.9 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEQ71307.1 - 0.025 13.5 0.0 0.23 10.3 0.0 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEQ71307.1 - 0.025 14.4 0.0 0.074 12.9 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEQ71307.1 - 0.028 12.9 0.0 0.064 11.7 0.0 1.6 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.1 EEQ71307.1 - 0.073 13.0 0.0 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.16 EEQ71307.1 - 0.15 11.6 0.0 0.4 10.2 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EEQ71307.1 - 0.18 10.8 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family SR-25 PF10500.4 EEQ71308.1 - 0.11 12.0 11.9 0.12 11.8 8.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PAP1 PF08601.5 EEQ71308.1 - 0.49 10.0 5.0 0.51 9.9 3.5 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 SSP160 PF06933.6 EEQ71308.1 - 0.66 7.8 18.8 0.76 7.6 13.0 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 WES_acyltransf PF03007.11 EEQ71308.1 - 1.6 8.2 5.4 1.7 8.1 3.7 1.1 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Pox_A12 PF04651.8 EEQ71308.1 - 2.1 8.4 9.4 2.6 8.1 6.5 1.1 1 0 0 1 1 1 0 Poxvirus A12 protein Macoilin PF09726.4 EEQ71308.1 - 3.4 5.8 8.0 3.6 5.7 5.5 1.0 1 0 0 1 1 1 0 Transmembrane protein Sporozoite_P67 PF05642.6 EEQ71308.1 - 6.7 4.4 9.9 8.1 4.1 6.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen LSM PF01423.17 EEQ71309.1 - 8.6e-20 70.0 0.1 1e-19 69.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF866 PF05907.8 EEQ71310.1 - 8.7e-45 152.0 0.3 1.1e-44 151.8 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Crystall PF00030.14 EEQ71310.1 - 0.018 14.8 0.1 0.74 9.7 0.0 2.7 2 1 1 3 3 3 0 Beta/Gamma crystallin DUF3431 PF11913.3 EEQ71311.1 - 2e-73 246.5 0.0 2.4e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DASH_Dad1 PF08649.5 EEQ71312.1 - 7.3e-23 80.0 2.3 1e-22 79.5 1.6 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 CobT PF06213.7 EEQ71312.1 - 0.0025 17.0 2.5 0.0028 16.8 1.8 1.1 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT DASH_Duo1 PF08651.5 EEQ71312.1 - 0.17 11.5 2.3 0.29 10.7 1.6 1.3 1 0 0 1 1 1 0 DASH complex subunit Duo1 Mpp10 PF04006.7 EEQ71312.1 - 0.18 10.1 5.4 0.23 9.7 3.8 1.0 1 0 0 1 1 1 0 Mpp10 protein Ras PF00071.17 EEQ71313.1 - 3.8e-48 162.9 0.0 4.8e-48 162.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ71313.1 - 4.5e-12 46.5 0.0 6.7e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ71313.1 - 3.7e-05 23.0 0.0 9e-05 21.7 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EEQ71313.1 - 0.061 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EEQ71313.1 - 0.073 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Sigma70_ner PF04546.8 EEQ71314.1 - 0.018 14.6 4.2 0.021 14.4 2.9 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region E7 PF00527.13 EEQ71314.1 - 0.14 12.3 0.3 0.21 11.7 0.2 1.2 1 0 0 1 1 1 0 E7 protein, Early protein CENP-B_dimeris PF09026.5 EEQ71314.1 - 2.2 8.5 17.5 3.4 7.9 12.2 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PAP2 PF01569.16 EEQ71315.1 - 8.7e-17 61.0 4.2 8.7e-17 61.0 2.9 2.0 2 1 0 2 2 2 1 PAP2 superfamily Peptidase_C48 PF02902.14 EEQ71316.1 - 5.2e-24 85.0 0.0 1.2e-23 83.8 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF2419 PF10343.4 EEQ71316.1 - 0.16 11.2 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2419) E1-E2_ATPase PF00122.15 EEQ71317.1 - 1.6e-53 181.1 1.8 1.6e-53 181.1 1.3 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EEQ71317.1 - 9.9e-27 94.7 0.0 1.7e-26 93.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEQ71317.1 - 4.3e-13 49.8 0.0 2.7e-12 47.2 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEQ71317.1 - 1.6e-08 34.4 0.0 4.4e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EEQ71317.1 - 0.00016 21.7 0.0 0.00034 20.6 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Glyco_hydro_16 PF00722.16 EEQ71318.1 - 0.0018 17.5 0.4 0.0089 15.3 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Reo_sigmaC PF04582.7 EEQ71320.1 - 0.0011 18.2 0.6 0.002 17.3 0.4 1.4 1 0 0 1 1 1 1 Reovirus sigma C capsid protein LPP PF04728.8 EEQ71320.1 - 0.0042 16.8 3.5 0.012 15.3 2.1 2.1 1 1 0 1 1 1 1 Lipoprotein leucine-zipper CENP-F_leu_zip PF10473.4 EEQ71320.1 - 0.011 15.5 0.5 0.022 14.6 0.3 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 EEQ71320.1 - 0.023 13.6 1.9 0.041 12.8 0.9 1.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 COG5 PF10392.4 EEQ71320.1 - 0.023 14.6 1.6 0.075 12.9 1.1 1.8 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Baculo_PEP_C PF04513.7 EEQ71320.1 - 0.055 13.2 0.9 0.13 12.0 0.6 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.3 EEQ71320.1 - 0.064 13.1 2.4 0.14 12.0 1.7 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF2046 PF09755.4 EEQ71320.1 - 0.07 12.0 0.2 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) TBPIP PF07106.8 EEQ71320.1 - 0.19 11.2 0.9 0.5 9.8 0.3 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 EEQ71320.1 - 0.22 11.8 4.5 0.51 10.6 3.1 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EEQ71320.1 - 0.23 11.0 2.9 0.23 11.0 1.3 1.5 2 0 0 2 2 2 0 IncA protein DUF1664 PF07889.7 EEQ71320.1 - 0.25 11.1 3.9 0.63 9.8 0.8 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) DENN PF02141.16 EEQ71321.1 - 2.8e-39 134.7 0.0 5e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EEQ71321.1 - 0.00022 21.1 0.0 0.00068 19.5 0.0 2.0 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.6 EEQ71321.1 - 0.00051 20.4 5.0 0.002 18.5 3.5 2.0 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF2570 PF10828.3 EEQ71321.1 - 1.5 8.4 9.0 0.93 9.1 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) DivIVA PF05103.8 EEQ71321.1 - 6.7 6.7 14.6 0.99 9.4 3.6 2.6 1 1 1 2 2 2 0 DivIVA protein ARL6IP6 PF15062.1 EEQ71322.1 - 0.047 13.5 0.3 0.12 12.3 0.1 1.7 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix zf-HIT PF04438.11 EEQ71324.1 - 3.7e-10 39.2 10.2 6.6e-10 38.4 7.1 1.4 1 0 0 1 1 1 1 HIT zinc finger adh_short PF00106.20 EEQ71325.1 - 3.3e-30 105.2 0.1 4.5e-30 104.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ71325.1 - 3.2e-25 89.3 0.1 4e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ71325.1 - 2.3e-13 50.2 0.2 4.9e-13 49.1 0.1 1.5 1 1 0 1 1 1 1 KR domain RabGAP-TBC PF00566.13 EEQ71326.1 - 3.8e-44 150.7 0.0 4.5e-43 147.2 0.0 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Death PF00531.17 EEQ71326.1 - 0.12 12.1 0.5 0.6 9.9 0.1 2.3 2 0 0 2 2 2 0 Death domain Ank_2 PF12796.2 EEQ71327.1 - 2.6e-31 107.8 0.0 5.5e-15 55.4 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ71327.1 - 2.9e-23 80.4 0.3 1.8e-07 30.5 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 EEQ71327.1 - 1.8e-19 69.7 0.0 4.9e-07 30.0 0.0 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ71327.1 - 2.4e-17 61.2 0.2 8.4e-05 22.4 0.0 4.8 4 1 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EEQ71327.1 - 9.9e-16 57.4 0.6 4.5e-07 29.9 0.1 4.6 4 0 0 4 4 4 3 Ankyrin repeats (many copies) F-box-like PF12937.2 EEQ71327.1 - 4.8e-06 26.2 0.0 8.4e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ71327.1 - 0.0015 18.1 0.0 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 F-box domain zf-B_box PF00643.19 EEQ71327.1 - 0.089 12.7 4.9 0.18 11.7 3.4 1.5 1 0 0 1 1 1 0 B-box zinc finger zf-HIT PF04438.11 EEQ71327.1 - 0.53 9.9 8.8 1.2 8.8 6.1 1.6 1 0 0 1 1 1 0 HIT zinc finger Herpes_BLRF2 PF05812.7 EEQ71328.1 - 0.016 15.0 1.4 0.016 15.0 1.0 2.5 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein DivIC PF04977.10 EEQ71328.1 - 0.024 14.1 2.3 0.024 14.1 1.6 3.8 4 0 0 4 4 4 0 Septum formation initiator Shugoshin_N PF07558.6 EEQ71328.1 - 0.056 13.1 1.2 5.6 6.7 0.1 3.1 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF1664 PF07889.7 EEQ71328.1 - 0.89 9.3 4.9 0.22 11.2 0.3 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) bZIP_2 PF07716.10 EEQ71328.1 - 2 8.2 32.9 0.17 11.7 1.3 4.9 4 1 1 5 5 5 0 Basic region leucine zipper bZIP_1 PF00170.16 EEQ71328.1 - 2.1 8.3 23.9 1.9 8.5 2.0 3.9 4 0 0 4 4 4 0 bZIP transcription factor DUF4407 PF14362.1 EEQ71328.1 - 3.9 6.3 13.5 1.5 7.7 5.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Lipoprotein_6 PF01441.14 EEQ71328.1 - 8.6 6.1 9.2 1.1 9.0 1.0 2.8 2 1 1 3 3 3 0 Lipoprotein CENP-F_leu_zip PF10473.4 EEQ71328.1 - 9.8 6.0 23.1 8.7 6.2 4.1 3.4 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FA_desaturase PF00487.19 EEQ71330.1 - 3e-13 49.8 18.3 3e-13 49.8 12.7 2.1 1 1 1 2 2 2 1 Fatty acid desaturase Pkinase PF00069.20 EEQ71331.1 - 8.8e-26 90.5 0.0 1.5e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EEQ71331.1 - 7e-16 57.4 2.9 3.1e-08 33.1 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat HEAT PF02985.17 EEQ71331.1 - 1.9e-10 39.8 5.9 0.084 12.9 0.1 6.8 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 EEQ71331.1 - 1.9e-05 24.8 1.2 0.62 10.3 0.0 4.2 3 1 1 4 4 4 3 HEAT repeats Pkinase_Tyr PF07714.12 EEQ71331.1 - 0.00029 19.9 0.0 0.00047 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase CPSF_A PF03178.10 EEQ71331.1 - 0.032 13.3 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 CPSF A subunit region HEAT_EZ PF13513.1 EEQ71331.1 - 0.29 11.6 4.6 1.7 9.2 0.2 4.1 4 0 0 4 4 4 0 HEAT-like repeat Casein_kappa PF00997.13 EEQ71333.1 - 0.0028 17.3 0.8 0.0045 16.6 0.6 1.3 1 0 0 1 1 1 1 Kappa casein zf-C2H2 PF00096.21 EEQ71334.1 - 5.7e-11 42.0 23.6 0.0027 17.9 5.7 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ71334.1 - 1.7e-10 40.4 15.6 0.0023 18.1 0.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EEQ71334.1 - 1.5e-05 25.0 18.4 0.057 13.7 0.3 3.7 3 0 0 3 3 3 3 Zinc-finger double domain Zn_ribbon_recom PF13408.1 EEQ71334.1 - 0.59 10.4 8.1 3.1 8.1 1.8 3.4 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain PDZ_assoc PF10600.4 EEQ71334.1 - 0.67 10.2 5.6 2 8.7 0.6 3.0 2 0 0 2 2 2 0 PDZ-associated domain of NMDA receptors zf-C2H2_2 PF12756.2 EEQ71334.1 - 0.87 9.7 9.7 4.1 7.5 1.7 2.6 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EEQ71334.1 - 1 9.3 10.1 0.046 13.6 2.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger TFIIS_C PF01096.13 EEQ71334.1 - 1.3 8.7 8.1 6.7 6.4 0.1 3.3 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.5 EEQ71334.1 - 4.8 7.2 12.9 2.3 8.2 0.6 3.1 3 0 0 3 3 3 0 Zinc ribbon domain Rpr2 PF04032.11 EEQ71334.1 - 7.3 6.5 10.3 25 4.8 7.0 2.0 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain NUDIX PF00293.23 EEQ71336.1 - 3.6e-28 97.8 0.0 5.2e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF202 PF02656.10 EEQ71337.1 - 9.1e-19 67.4 0.6 9.1e-19 67.4 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) COX4_pro_2 PF07835.7 EEQ71337.1 - 0.21 11.6 1.5 0.78 9.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV MatE PF01554.13 EEQ71338.1 - 7.4e-53 178.4 28.7 4.7e-29 101.0 7.1 2.4 2 0 0 2 2 2 2 MatE DnaJ PF00226.26 EEQ71339.1 - 6.5e-15 54.6 3.8 9.2e-15 54.1 0.5 2.7 3 0 0 3 3 3 1 DnaJ domain DEAD PF00270.24 EEQ71340.1 - 7.5e-45 152.4 0.1 1.7e-44 151.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EEQ71340.1 - 1.3e-24 85.4 0.1 2.7e-24 84.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EEQ71340.1 - 1.4e-20 72.9 0.0 3.7e-20 71.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EEQ71340.1 - 0.00068 18.5 0.0 0.0013 17.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C_2 PF13307.1 EEQ71340.1 - 0.002 18.1 0.0 0.0055 16.6 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.10 EEQ71340.1 - 0.002 17.9 0.0 0.002 17.9 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AA_permease PF00324.16 EEQ71341.1 - 2.9e-123 411.7 40.2 3.5e-123 411.4 27.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ71341.1 - 9.5e-39 133.1 46.3 1.8e-38 132.1 31.9 1.6 1 1 0 1 1 1 1 Amino acid permease Zn_clus PF00172.13 EEQ71344.1 - 0.0002 21.1 12.0 0.00032 20.5 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.24 EEQ71345.1 - 1.1e-44 151.9 0.0 2.6e-44 150.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ71345.1 - 6.9e-20 70.6 0.2 3.7e-19 68.3 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EEQ71345.1 - 2.2e-18 65.8 1.7 2.2e-18 65.8 1.2 2.3 2 0 0 2 2 2 1 DBP10CT (NUC160) domain RPA_C PF08784.6 EEQ71346.1 - 1e-13 51.5 0.0 4e-13 49.6 0.0 2.0 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EEQ71346.1 - 5.7e-06 26.0 0.0 9.9e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PAPS_reduct PF01507.14 EEQ71347.1 - 1e-27 97.0 0.0 6.3e-26 91.2 0.0 2.2 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family RRM_1 PF00076.17 EEQ71348.1 - 1.1e-21 76.1 0.2 1.2e-10 40.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ71348.1 - 1.3e-13 50.6 0.1 7.8e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ71348.1 - 0.00051 19.8 0.6 0.38 10.6 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.15 EEQ71349.1 - 1.5e-60 204.3 0.0 2.1e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EEQ71349.1 - 6.1e-33 113.8 1.9 1e-32 113.0 1.3 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EEQ71349.1 - 2.8e-22 79.3 0.0 1.5e-21 76.9 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Pkinase PF00069.20 EEQ71350.1 - 1.1e-09 37.8 0.0 2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ71350.1 - 0.00069 18.7 0.2 0.0051 15.9 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ71350.1 - 0.00092 19.0 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ71350.1 - 0.011 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 EEQ71350.1 - 0.023 13.7 0.2 0.046 12.7 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.3 EEQ71350.1 - 0.048 13.0 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 MOR2-PAG1_N PF14222.1 EEQ71351.1 - 2.1e-227 756.1 0.0 4e-227 755.2 0.0 1.5 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EEQ71351.1 - 6.5e-97 324.3 0.0 1.9e-96 322.8 0.0 1.9 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EEQ71351.1 - 2e-34 118.4 16.3 4.3e-18 64.3 0.1 4.3 3 1 1 4 4 4 3 Cell morphogenesis central region HET PF06985.6 EEQ71352.1 - 3e-21 76.0 0.0 6.1e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NAD_binding_2 PF03446.10 EEQ71353.1 - 4.8e-34 117.5 0.0 7.1e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EEQ71353.1 - 2.3e-31 108.3 0.0 3.5e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EEQ71353.1 - 4.9e-07 30.0 0.0 1.4e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.10 EEQ71353.1 - 0.00025 19.9 0.0 0.00039 19.2 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.17 EEQ71353.1 - 0.059 13.8 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Glyco_tranf_2_2 PF10111.4 EEQ71353.1 - 0.17 10.9 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 MMS1_N PF10433.4 EEQ71354.1 - 9.6e-80 268.1 0.0 2e-79 267.0 0.0 1.5 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EEQ71354.1 - 3.8e-65 220.0 0.0 3.8e-60 203.6 0.0 4.2 3 1 1 4 4 4 2 CPSF A subunit region DUF2460 PF09343.5 EEQ71354.1 - 0.11 11.8 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 2217 (DUF2460) PGA2 PF07543.7 EEQ71355.1 - 2.9e-44 150.2 0.3 3.4e-44 150.0 0.2 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 INCENP_ARK-bind PF03941.10 EEQ71355.1 - 0.066 13.0 0.1 0.2 11.5 0.1 1.7 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region CENP-S PF15630.1 EEQ71356.1 - 1.8e-13 50.4 0.0 2.4e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S MARVEL PF01284.18 EEQ71357.1 - 9.4e-07 28.7 11.0 1.4e-06 28.1 7.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain AgrD PF05931.6 EEQ71358.1 - 0.1 12.2 0.1 2.8 7.6 0.1 2.5 2 0 0 2 2 2 0 Staphylococcal AgrD protein DUF2235 PF09994.4 EEQ71359.1 - 3e-104 348.3 0.2 3.9e-104 347.9 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Microcin PF03526.8 EEQ71359.1 - 0.22 11.1 0.7 0.48 10.0 0.5 1.4 1 0 0 1 1 1 0 Colicin E1 (microcin) immunity protein An_peroxidase PF03098.10 EEQ71360.1 - 1.4e-98 330.6 0.0 3.4e-96 322.7 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EEQ71360.1 - 7.1e-05 21.5 0.1 0.0002 19.9 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 Amidase PF01425.16 EEQ71363.1 - 4e-39 134.7 0.1 1.9e-38 132.4 0.1 1.8 2 0 0 2 2 2 1 Amidase TPR_12 PF13424.1 EEQ71364.1 - 1.4e-23 82.5 13.3 1.7e-10 40.6 0.2 6.5 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.1 EEQ71364.1 - 9.1e-12 44.5 7.5 0.018 14.9 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ71364.1 - 3.8e-10 38.7 1.8 0.13 12.1 0.0 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 EEQ71364.1 - 5.6e-10 38.5 0.0 1.1e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily TPR_11 PF13414.1 EEQ71364.1 - 1.9e-09 37.0 8.7 0.00079 19.0 0.3 4.5 2 2 3 5 5 5 3 TPR repeat NB-ARC PF00931.17 EEQ71364.1 - 3.3e-09 36.0 0.0 6.5e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.1 EEQ71364.1 - 2.4e-07 30.0 6.7 0.32 10.8 0.0 5.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ71364.1 - 3.1e-07 29.7 9.7 0.43 10.6 0.0 6.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ71364.1 - 4.9e-07 29.0 7.5 0.12 12.0 0.0 5.3 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_16 PF13191.1 EEQ71364.1 - 8e-05 22.6 0.1 0.00079 19.4 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEQ71364.1 - 0.00037 20.6 0.0 0.0018 18.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain TPR_14 PF13428.1 EEQ71364.1 - 0.0017 18.8 5.8 15 6.5 0.0 6.8 6 2 2 8 8 8 0 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ71364.1 - 0.0097 16.0 0.3 82 3.7 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2225 PF09986.4 EEQ71364.1 - 0.011 15.1 0.1 0.026 13.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_4 PF07721.9 EEQ71364.1 - 0.26 11.8 2.6 20 5.9 0.0 4.4 5 0 0 5 5 3 0 Tetratricopeptide repeat Glyco_hydro_31 PF01055.21 EEQ71365.1 - 1.6e-109 366.6 6.9 3.4e-109 365.6 4.8 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EEQ71365.1 - 0.0027 17.5 1.6 0.0066 16.2 0.2 2.3 3 0 0 3 3 3 1 Galactose mutarotase-like Hexapep PF00132.19 EEQ71366.1 - 1.3e-06 27.5 9.9 0.00036 19.9 2.1 4.4 3 1 2 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EEQ71366.1 - 1.4e-06 27.7 0.8 0.017 14.6 0.2 3.0 1 1 1 2 2 2 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EEQ71366.1 - 0.041 12.4 0.1 0.067 11.7 0.0 1.3 2 0 0 2 2 2 0 L-fucokinase Arf PF00025.16 EEQ71367.1 - 7e-74 246.8 0.1 8e-74 246.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EEQ71367.1 - 1.5e-11 43.9 0.0 1.8e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EEQ71367.1 - 2e-11 43.4 0.0 2.5e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EEQ71367.1 - 3.1e-11 42.8 0.0 3.8e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EEQ71367.1 - 5.6e-11 41.7 1.8 1.5e-07 30.4 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EEQ71367.1 - 3.1e-06 27.6 0.0 4.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEQ71367.1 - 0.00017 21.5 0.1 0.00057 19.8 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EEQ71367.1 - 0.025 13.6 0.1 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase tRNA-synt_1f PF01921.13 EEQ71369.1 - 0.016 13.9 0.1 0.26 9.9 0.0 2.2 2 1 0 2 2 2 0 tRNA synthetases class I (K) F-box-like PF12937.2 EEQ71372.1 - 5.6e-05 22.7 0.0 0.00028 20.5 0.0 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ71372.1 - 0.0084 15.7 0.5 0.16 11.6 0.0 2.5 2 0 0 2 2 2 1 F-box domain MFS_1 PF07690.11 EEQ71373.1 - 1.3e-29 103.0 50.7 8.6e-29 100.3 31.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MCM PF00493.18 EEQ71374.1 - 7.2e-138 458.9 0.0 1e-137 458.3 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EEQ71374.1 - 5.2e-37 127.2 30.3 5.2e-37 127.2 21.0 2.4 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EEQ71374.1 - 4.1e-18 66.0 0.0 8.9e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEQ71374.1 - 1.2e-08 34.3 0.1 2.4e-06 26.8 0.0 2.6 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEQ71374.1 - 7.5e-06 25.7 0.1 2.7e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EEQ71374.1 - 0.0015 18.1 0.0 0.01 15.4 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EEQ71374.1 - 0.0015 17.9 0.2 0.01 15.2 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain zf-TFIIB PF13453.1 EEQ71374.1 - 0.041 13.0 1.2 0.085 12.0 0.8 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger Zn_ribbon_2 PF12674.2 EEQ71374.1 - 0.11 12.8 0.6 0.43 10.9 0.4 2.0 1 0 0 1 1 1 0 Putative zinc ribbon domain zf-UBR PF02207.15 EEQ71375.1 - 5.6e-16 58.0 6.2 5.6e-16 58.0 4.3 3.0 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) DUF913 PF06025.7 EEQ71375.1 - 0.71 8.5 2.2 1.3 7.6 1.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Tim54 PF11711.3 EEQ71375.1 - 2.9 6.3 6.6 0.85 8.1 1.3 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Pkinase PF00069.20 EEQ71376.1 - 8.9e-62 208.5 0.0 1.1e-61 208.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ71376.1 - 2.4e-29 102.2 0.0 3.9e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ71376.1 - 0.058 12.3 0.0 0.093 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EEQ71376.1 - 0.14 11.8 0.1 0.47 10.1 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Claudin_2 PF13903.1 EEQ71377.1 - 0.004 16.8 4.7 0.004 16.8 3.3 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction MARVEL PF01284.18 EEQ71377.1 - 0.65 9.8 12.7 0.72 9.6 8.3 1.5 1 1 0 1 1 1 0 Membrane-associating domain SdpI PF13630.1 EEQ71377.1 - 9.6 6.0 12.7 0.49 10.1 3.0 2.5 1 1 1 2 2 2 0 SdpI/YhfL protein family DUF1688 PF07958.6 EEQ71378.1 - 7.5e-159 528.7 0.0 8.5e-159 528.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) DUF2419 PF10343.4 EEQ71378.1 - 0.0013 18.0 0.0 0.045 13.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2419) Sugar_tr PF00083.19 EEQ71379.1 - 1.9e-83 280.5 15.6 2.4e-83 280.2 10.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ71379.1 - 8.1e-32 110.2 63.1 5.4e-29 101.0 22.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEQ71379.1 - 0.00025 19.3 3.2 0.00025 19.3 2.2 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PsbX PF06596.6 EEQ71379.1 - 0.057 13.0 0.7 0.057 13.0 0.5 3.3 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) Mannosyl_trans3 PF11051.3 EEQ71381.1 - 2.1e-67 227.3 0.0 2.7e-67 226.9 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative TPT PF03151.11 EEQ71382.1 - 2.2e-14 53.3 10.0 2.2e-14 53.3 6.9 2.4 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EEQ71382.1 - 0.00015 20.8 20.8 0.00018 20.5 14.4 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EEQ71382.1 - 0.00026 21.0 7.4 0.00026 21.0 5.1 2.9 2 2 1 3 3 3 2 EamA-like transporter family Mac-1 PF09028.5 EEQ71382.1 - 0.15 10.8 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Mac 1 EmrE PF13536.1 EEQ71382.1 - 5.6 7.2 29.7 1.3 9.2 5.9 3.9 3 1 1 4 4 4 0 Multidrug resistance efflux transporter Ste5 PF11610.3 EEQ71383.1 - 0.048 13.2 0.1 0.092 12.2 0.1 1.4 1 0 0 1 1 1 0 Scaffold protein Ste5-Fus5 binding region Glyco_transf_17 PF04724.8 EEQ71384.1 - 3.3e-48 164.5 0.2 4.2e-48 164.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 17 MIS13 PF08202.6 EEQ71385.1 - 7.6e-46 156.5 0.7 2.5e-45 154.8 0.5 1.8 1 1 0 1 1 1 1 Mis12-Mtw1 protein family PS_Dcarbxylase PF02666.10 EEQ71386.1 - 5.2e-53 179.3 0.0 7.5e-53 178.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EEQ71386.1 - 3.2e-24 84.5 0.1 1.1e-13 50.8 0.1 2.4 2 0 0 2 2 2 2 C2 domain DUF1212 PF06738.7 EEQ71389.1 - 1.1e-47 162.0 10.0 3e-45 154.0 0.2 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EEQ71389.1 - 9.6e-34 116.1 7.6 9.6e-34 116.1 5.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) DUF997 PF06196.7 EEQ71389.1 - 0.18 11.3 0.2 0.44 10.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF997) Ank_2 PF12796.2 EEQ71390.1 - 2e-48 162.6 5.8 9.1e-15 54.7 0.1 6.3 4 2 2 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ71390.1 - 3.1e-46 152.9 5.8 9e-06 25.2 0.0 10.7 10 1 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.1 EEQ71390.1 - 4.5e-43 144.8 7.8 1.7e-10 41.0 0.0 8.5 5 3 3 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ71390.1 - 3e-26 88.8 7.6 0.026 14.7 0.0 11.1 11 0 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.1 EEQ71390.1 - 6.9e-26 89.6 15.7 1.2e-05 25.3 0.1 8.2 5 4 3 8 8 8 8 Ankyrin repeats (many copies) RR_TM4-6 PF06459.7 EEQ71392.1 - 2.4 7.9 29.6 3.3 7.5 20.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.11 EEQ71392.1 - 3.4 7.4 11.2 4.3 7.1 7.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SprA-related PF12118.3 EEQ71392.1 - 5 6.3 23.6 7.2 5.8 16.3 1.3 1 0 0 1 1 1 0 SprA-related family Daxx PF03344.10 EEQ71392.1 - 6.8 5.0 42.1 8.2 4.7 29.2 1.0 1 0 0 1 1 1 0 Daxx Family Asp-B-Hydro_N PF05279.6 EEQ71392.1 - 8.2 6.1 32.7 10 5.8 22.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ank PF00023.25 EEQ71394.1 - 1e-13 50.3 2.0 6e-10 38.4 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EEQ71394.1 - 6.2e-13 48.9 0.1 1.6e-08 34.7 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEQ71394.1 - 5.6e-11 42.3 0.4 6.8e-07 29.3 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEQ71394.1 - 7e-10 39.1 0.5 3.1e-06 27.5 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ71394.1 - 8.6e-10 37.9 0.5 8.3e-07 28.6 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat KilA-N PF04383.8 EEQ71394.1 - 6.5e-05 22.5 0.4 0.00036 20.1 0.0 2.4 2 1 0 2 2 2 1 KilA-N domain MTBP_C PF14920.1 EEQ71394.1 - 0.0033 16.9 3.4 0.0033 16.9 2.4 2.1 3 0 0 3 3 3 1 MDM2-binding HALZ PF02183.13 EEQ71394.1 - 0.031 13.9 3.6 0.13 12.0 0.5 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF948 PF06103.6 EEQ71394.1 - 0.046 13.5 1.7 0.19 11.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NDUF_B7 PF05676.8 EEQ71395.1 - 2.1e-32 110.3 4.0 2.4e-32 110.1 2.8 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EEQ71395.1 - 0.12 12.1 3.2 0.15 11.8 2.1 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like GCS PF03074.11 EEQ71396.1 - 4.9e-137 456.9 1.2 8.7e-99 331.0 0.1 3.1 1 1 1 2 2 2 2 Glutamate-cysteine ligase GCS2 PF04107.8 EEQ71396.1 - 0.054 12.5 0.0 0.16 11.0 0.0 1.7 2 0 0 2 2 2 0 Glutamate-cysteine ligase family 2(GCS2) VWA_3 PF13768.1 EEQ71397.1 - 4.8e-29 101.0 0.0 8.1e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 EEQ71397.1 - 3.7e-21 74.9 0.0 8.6e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VIT_2 PF13757.1 EEQ71397.1 - 3.6e-14 51.9 0.0 1.1e-13 50.4 0.0 1.8 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 EEQ71397.1 - 4.2e-12 46.5 0.0 7.5e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EEQ71397.1 - 3.7e-06 26.7 0.0 7.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Synaptobrevin PF00957.16 EEQ71397.1 - 0.00046 19.7 0.0 0.00097 18.6 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin vWA-TerF-like PF10138.4 EEQ71397.1 - 0.0048 16.7 0.0 0.0096 15.7 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_CoxE PF05762.9 EEQ71397.1 - 0.066 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein GATA PF00320.22 EEQ71399.1 - 8.7e-15 53.7 5.2 2e-14 52.6 3.6 1.7 1 0 0 1 1 1 1 GATA zinc finger zf-RING_3 PF14369.1 EEQ71399.1 - 0.28 11.1 1.9 0.6 10.1 1.3 1.5 1 0 0 1 1 1 0 zinc-finger Acetyltransf_4 PF13420.1 EEQ71403.1 - 1.3e-07 31.7 0.0 8.5e-07 29.0 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEQ71403.1 - 5.1e-06 26.4 0.0 9.9e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EEQ71403.1 - 0.00012 22.1 0.0 0.00044 20.3 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEQ71403.1 - 0.00037 20.5 0.0 0.00075 19.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEQ71403.1 - 0.00074 19.6 0.0 0.0012 18.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEQ71403.1 - 0.0011 18.7 0.0 0.012 15.4 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ71403.1 - 0.034 13.8 0.0 0.13 12.0 0.0 1.9 1 1 1 2 2 2 0 FR47-like protein Macro PF01661.16 EEQ71404.1 - 2.3e-39 133.9 0.0 4e-39 133.1 0.0 1.4 1 0 0 1 1 1 1 Macro domain Peptidase_S24 PF00717.18 EEQ71405.1 - 7e-08 31.9 0.0 2e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EEQ71405.1 - 0.065 12.7 0.0 11 5.5 0.0 2.4 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 PH_4 PF15404.1 EEQ71406.1 - 1e-62 210.9 0.2 1e-60 204.4 0.0 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain Spo7_2_N PF15407.1 EEQ71406.1 - 3.5e-25 87.2 0.6 9.3e-25 85.8 0.4 1.8 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.24 EEQ71406.1 - 1.3e-08 34.9 0.4 0.023 14.8 0.0 4.3 5 1 0 5 5 5 2 PH domain PH_6 PF15406.1 EEQ71406.1 - 0.00064 19.7 0.1 1.9 8.6 0.0 2.8 2 0 0 2 2 2 2 Pleckstrin homology domain GLTP PF08718.6 EEQ71407.1 - 9.8e-33 113.2 0.0 2.6e-32 111.9 0.0 1.6 1 1 0 1 1 1 1 Glycolipid transfer protein (GLTP) Hydrolase PF00702.21 EEQ71408.1 - 3.2e-22 79.9 0.0 9.2e-22 78.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EEQ71408.1 - 4.8e-21 74.8 0.0 2.1e-20 72.7 0.0 2.0 1 1 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EEQ71408.1 - 2.2e-20 73.6 0.0 3.9e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEQ71408.1 - 0.0014 18.2 0.2 0.017 14.7 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ71408.1 - 0.0077 16.1 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit S6PP PF05116.8 EEQ71408.1 - 0.12 11.6 1.3 0.43 9.8 0.1 2.4 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase SIR2 PF02146.12 EEQ71409.1 - 1.4e-27 96.6 0.0 3.1e-27 95.4 0.0 1.6 1 1 0 1 1 1 1 Sir2 family Glyco_transf_28 PF03033.15 EEQ71409.1 - 0.07 12.9 0.1 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Ank_5 PF13857.1 EEQ71410.1 - 0.014 15.6 0.1 0.024 14.9 0.1 1.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEQ71410.1 - 0.024 14.9 0.0 0.029 14.6 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Peptidase_M3_N PF08439.5 EEQ71410.1 - 0.028 14.4 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Oligopeptidase F Ank PF00023.25 EEQ71410.1 - 0.071 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Ankyrin repeat FYVE PF01363.16 EEQ71411.1 - 3.3e-24 84.5 24.7 3.9e-17 61.9 3.8 2.9 3 0 0 3 3 3 2 FYVE zinc finger zf-AN1 PF01428.11 EEQ71411.1 - 0.00081 19.2 4.2 0.00081 19.2 2.9 3.6 4 0 0 4 4 4 2 AN1-like Zinc finger zf-Di19 PF05605.7 EEQ71411.1 - 0.0065 16.5 14.6 0.031 14.3 0.0 3.2 3 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding DUF4606 PF15379.1 EEQ71411.1 - 0.014 15.4 0.7 9.7 6.3 0.3 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4606) FYVE_2 PF02318.11 EEQ71411.1 - 3.8 7.4 18.0 0.86 9.5 2.6 3.2 3 1 0 3 3 3 0 FYVE-type zinc finger PKD_channel PF08016.7 EEQ71412.1 - 9e-06 24.3 16.8 0.00016 20.2 11.7 2.2 1 1 0 1 1 1 1 Polycystin cation channel CAML PF14963.1 EEQ71412.1 - 2.1 7.6 3.7 3.9 6.7 2.6 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand EIF_2_alpha PF07541.7 EEQ71413.1 - 1.1e-38 131.4 0.0 2.4e-38 130.3 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EEQ71413.1 - 4.4e-13 49.1 0.7 9.5e-13 48.0 0.5 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Sulfate_transp PF00916.15 EEQ71414.1 - 1.5e-52 178.3 5.0 1.5e-52 178.3 3.5 2.4 2 1 1 3 3 3 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EEQ71414.1 - 1.3e-26 92.0 4.0 5.1e-26 90.1 2.5 2.4 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EEQ71414.1 - 1.4e-11 43.8 0.0 2.7e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain HTH_Tnp_1 PF01527.15 EEQ71414.1 - 0.1 12.5 0.0 0.48 10.4 0.0 2.1 1 1 0 1 1 1 0 Transposase MttA_Hcf106 PF02416.11 EEQ71415.1 - 2.5 7.2 4.5 4.2 6.5 3.0 1.5 1 1 0 1 1 1 0 mttA/Hcf106 family CENP-L PF13092.1 EEQ71416.1 - 2.4e-59 199.7 0.0 3.2e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Acetyltransf_1 PF00583.19 EEQ71417.1 - 1.5e-08 34.5 0.1 3.2e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ71417.1 - 6.1e-06 26.3 0.1 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEQ71417.1 - 9.9e-05 22.4 0.1 0.00031 20.8 0.0 1.7 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEQ71417.1 - 0.049 13.4 0.0 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ71417.1 - 0.055 13.2 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein ArsA_ATPase PF02374.10 EEQ71417.1 - 0.15 11.0 0.3 0.2 10.6 0.2 1.1 1 0 0 1 1 1 0 Anion-transporting ATPase Palm_thioest PF02089.10 EEQ71418.1 - 2.4e-51 174.3 0.0 3.1e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.6 EEQ71418.1 - 0.0017 17.4 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.2 EEQ71418.1 - 0.019 14.7 0.0 0.44 10.2 0.0 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase family zf-C2H2 PF00096.21 EEQ71420.1 - 1.6 9.2 7.0 6.1 7.4 0.1 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type KTI12 PF08433.5 EEQ71421.1 - 6e-63 212.5 0.0 6.2e-62 209.2 0.0 2.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EEQ71421.1 - 0.00053 19.8 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Methyltransf_16 PF10294.4 EEQ71422.1 - 4.7e-11 42.4 0.0 9.9e-10 38.1 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EEQ71422.1 - 0.014 15.1 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 EEQ71422.1 - 0.05 12.7 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Laminin_N PF00055.12 EEQ71425.1 - 0.0078 15.2 0.2 0.011 14.7 0.1 1.1 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) F-box PF00646.28 EEQ71427.1 - 0.00077 19.0 0.0 0.0021 17.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EEQ71427.1 - 0.01 15.5 0.1 0.036 13.7 0.0 2.0 1 0 0 1 1 1 1 F-box-like AlaDh_PNT_N PF05222.10 EEQ71428.1 - 1.9e-26 92.7 0.0 3e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EEQ71428.1 - 3.8e-14 52.5 0.0 5.5e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain BAR PF03114.13 EEQ71429.1 - 4.5e-61 206.3 8.9 5.4e-61 206.0 6.2 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EEQ71429.1 - 3.6e-16 58.2 0.1 7.4e-16 57.2 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEQ71429.1 - 4e-15 55.1 0.1 8.3e-15 54.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EEQ71429.1 - 4.5e-11 42.0 0.1 1.3e-10 40.5 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain AHS1 PF02682.11 EEQ71429.1 - 0.053 12.9 0.6 0.17 11.3 0.4 1.9 1 1 0 1 1 1 0 Allophanate hydrolase subunit 1 Vps5 PF09325.5 EEQ71429.1 - 0.096 11.9 11.1 1.1 8.4 7.7 2.1 1 1 0 1 1 1 0 Vps5 C terminal like DUF2370 PF10176.4 EEQ71429.1 - 0.14 11.4 0.1 0.14 11.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) TarH PF02203.10 EEQ71429.1 - 0.61 9.8 3.6 1.9 8.2 0.3 2.2 2 0 0 2 2 2 0 Tar ligand binding domain homologue YlqD PF11068.3 EEQ71429.1 - 1.4 8.9 10.7 3 7.8 0.1 3.1 2 1 1 3 3 3 0 YlqD protein TMPIT PF07851.8 EEQ71429.1 - 9.3 5.2 9.5 0.7 8.8 0.3 2.1 1 1 1 2 2 2 0 TMPIT-like protein BRE1 PF08647.6 EEQ71429.1 - 9.6 6.2 12.6 0.64 10.0 0.3 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase FAD_binding_4 PF01565.18 EEQ71430.1 - 6.1e-19 67.8 0.0 3.7e-18 65.3 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EEQ71430.1 - 2.9e-05 23.8 0.0 7.8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EEQ71430.1 - 0.076 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Aminotran_5 PF00266.14 EEQ71431.1 - 1.1e-95 320.5 0.0 1.7e-95 319.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EEQ71431.1 - 5.1e-07 29.1 0.0 7.8e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EEQ71431.1 - 1.4e-06 27.5 0.0 2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EEQ71431.1 - 0.00026 20.1 0.0 0.00065 18.8 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 EEQ71431.1 - 0.0018 16.7 0.0 0.0027 16.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 EEQ71431.1 - 0.062 11.5 0.0 0.095 10.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme IDO PF01231.13 EEQ71432.1 - 9.2e-171 567.9 0.0 1.1e-170 567.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 EEQ71432.1 - 0.063 11.7 0.0 0.2 10.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) CsbD PF05532.7 EEQ71434.1 - 8.5e-05 22.1 7.0 8.5e-05 22.1 4.8 4.1 4 1 1 5 5 5 1 CsbD-like ERG2_Sigma1R PF04622.7 EEQ71435.1 - 1.7e-71 239.9 0.0 1.9e-71 239.7 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein UEV PF05743.8 EEQ71436.1 - 2.3e-36 124.1 0.1 3.9e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EEQ71436.1 - 2e-19 68.9 0.3 5.2e-19 67.6 0.0 1.9 2 0 0 2 2 2 1 Vps23 core domain ADIP PF11559.3 EEQ71436.1 - 9.7e-05 22.3 6.0 0.00021 21.2 4.1 1.5 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding IncA PF04156.9 EEQ71436.1 - 0.00017 21.2 0.3 0.00031 20.4 0.2 1.3 1 0 0 1 1 1 1 IncA protein UQ_con PF00179.21 EEQ71436.1 - 0.00032 20.1 1.7 0.00039 19.8 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Reo_sigmaC PF04582.7 EEQ71436.1 - 0.011 14.9 9.1 0.017 14.3 6.3 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Tektin PF03148.9 EEQ71436.1 - 0.015 13.9 0.7 0.024 13.2 0.5 1.2 1 0 0 1 1 1 0 Tektin family TBPIP PF07106.8 EEQ71436.1 - 0.089 12.3 0.4 0.15 11.6 0.3 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Cep57_MT_bd PF06657.8 EEQ71436.1 - 0.11 12.4 0.4 0.25 11.3 0.2 1.6 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF4618 PF15397.1 EEQ71436.1 - 0.14 11.4 0.7 0.21 10.8 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Snapin_Pallidin PF14712.1 EEQ71436.1 - 0.16 12.2 3.6 0.3 11.4 2.5 1.5 1 0 0 1 1 1 0 Snapin/Pallidin NTR2 PF15458.1 EEQ71436.1 - 0.32 10.1 2.9 0.77 8.9 2.0 1.6 1 0 0 1 1 1 0 Nineteen complex-related protein 2 TMF_TATA_bd PF12325.3 EEQ71436.1 - 2.7 7.7 4.1 0.99 9.1 1.0 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding STE2 PF02116.10 EEQ71437.1 - 1.5e-99 332.6 18.3 1.8e-99 332.3 12.7 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR APH PF01636.18 EEQ71438.1 - 1.7e-07 31.2 0.1 0.001 18.8 0.0 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EEQ71438.1 - 3.8e-07 29.3 0.1 0.0013 17.8 0.0 3.4 4 0 0 4 4 4 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EEQ71438.1 - 0.00024 20.3 0.0 0.00067 18.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EEQ71438.1 - 0.01 15.1 0.0 0.58 9.4 0.0 2.5 3 0 0 3 3 3 0 RIO1 family Aldo_ket_red PF00248.16 EEQ71439.1 - 1.2e-14 53.7 0.0 1.9e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.15 EEQ71440.1 - 4.9e-53 178.6 2.1 5.8e-53 178.4 1.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Maf1 PF09174.5 EEQ71441.1 - 7.6e-65 218.1 0.0 1.2e-64 217.4 0.0 1.3 1 0 0 1 1 1 1 Maf1 regulator Type_III_YscX PF09474.5 EEQ71441.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) Filament PF00038.16 EEQ71442.1 - 8.9e-06 25.3 16.4 8.9e-06 25.3 11.4 4.3 3 1 2 5 5 5 1 Intermediate filament protein TMF_DNA_bd PF12329.3 EEQ71442.1 - 0.0081 15.9 9.0 0.0081 15.9 6.2 7.2 7 1 0 7 7 7 3 TATA element modulatory factor 1 DNA binding Trypan_PARP PF05887.6 EEQ71442.1 - 1.7 8.4 21.6 0.024 14.4 9.5 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Reo_sigmaC PF04582.7 EEQ71442.1 - 5.9 5.9 13.7 6.1 5.9 4.8 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein COPIIcoated_ERV PF07970.7 EEQ71443.1 - 4.2e-31 108.3 0.1 8.1e-30 104.0 0.1 2.1 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EEQ71443.1 - 3.6e-24 84.5 0.0 6.4e-24 83.7 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pkinase PF00069.20 EEQ71444.1 - 3.2e-59 200.1 0.0 5e-59 199.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ71444.1 - 3.1e-21 75.6 0.0 5.1e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ71444.1 - 0.053 13.2 0.0 0.23 11.1 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Slu7 PF11708.3 EEQ71445.1 - 2.8e-78 262.9 21.2 2.8e-78 262.9 14.7 2.2 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EEQ71445.1 - 0.019 14.6 0.8 0.04 13.5 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle DNA_pol_B PF00136.16 EEQ71446.1 - 2.4e-92 310.1 0.0 4.3e-92 309.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EEQ71446.1 - 4e-25 88.3 0.1 9e-13 47.7 0.0 2.7 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EEQ71446.1 - 6.1e-18 64.5 4.1 6.1e-18 64.5 2.8 1.9 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta GRIM-19 PF06212.7 EEQ71446.1 - 0.015 14.9 0.1 0.053 13.2 0.1 1.9 1 0 0 1 1 1 0 GRIM-19 protein DsrD PF08679.6 EEQ71446.1 - 0.015 15.2 0.0 0.055 13.4 0.0 2.0 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) Acetyltransf_9 PF13527.1 EEQ71447.1 - 8.7e-07 28.8 0.0 2.1e-05 24.3 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEQ71447.1 - 4.1e-06 26.7 0.0 6.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ71447.1 - 1.9e-05 24.7 0.0 5.1e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEQ71447.1 - 6.2e-05 23.1 0.0 0.012 15.6 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ71447.1 - 0.14 11.9 0.1 1.1 8.9 0.0 2.2 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_1 PF00583.19 EEQ71448.1 - 1.4e-05 25.0 0.0 9.5e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ71448.1 - 0.00046 20.2 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEQ71448.1 - 0.0022 17.8 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEQ71448.1 - 0.0025 17.9 0.0 0.0096 16.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ71448.1 - 0.021 14.5 0.0 0.057 13.1 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 EEQ71448.1 - 0.035 13.9 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase HTH_35 PF13693.1 EEQ71448.1 - 0.082 12.7 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Ank_2 PF12796.2 EEQ71449.1 - 2.6e-34 117.4 9.8 2.5e-09 37.3 0.1 5.4 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ71449.1 - 3.9e-26 89.5 0.6 2.3e-06 27.0 0.0 8.4 8 1 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 EEQ71449.1 - 2.5e-22 78.3 5.6 3.3e-06 27.1 0.1 7.0 5 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEQ71449.1 - 7.1e-20 70.9 5.1 0.00048 20.5 0.0 6.9 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ71449.1 - 2e-15 55.3 6.1 0.033 14.4 0.0 8.6 9 0 0 9 9 9 4 Ankyrin repeat HLH PF00010.21 EEQ71449.1 - 0.033 13.8 0.1 0.084 12.5 0.0 1.7 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain DUF2404 PF10296.4 EEQ71450.1 - 1.2e-29 102.2 0.0 3.1e-29 100.9 0.0 1.7 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) ANTH PF07651.11 EEQ71451.1 - 8e-70 234.7 0.0 8e-70 234.7 0.0 3.0 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.12 EEQ71451.1 - 5.4e-64 214.7 8.3 5.4e-64 214.7 5.8 6.4 3 2 3 7 7 7 1 I/LWEQ domain Med15 PF09606.5 EEQ71451.1 - 0.26 9.4 30.9 0.51 8.4 21.4 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HMG_box PF00505.14 EEQ71455.1 - 2.7e-13 49.9 2.8 1.3e-12 47.7 1.9 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EEQ71455.1 - 0.0038 17.5 0.3 0.016 15.5 0.2 1.9 1 1 0 1 1 1 1 HMG-box domain UPF0139 PF03669.8 EEQ71457.1 - 0.00014 21.3 0.6 0.038 13.5 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0139) 60KD_IMP PF02096.15 EEQ71457.1 - 0.036 13.7 1.1 0.04 13.5 0.7 1.1 1 0 0 1 1 1 0 60Kd inner membrane protein LppC PF04348.8 EEQ71457.1 - 0.16 10.5 0.2 0.17 10.3 0.1 1.1 1 0 0 1 1 1 0 LppC putative lipoprotein COX6A PF02046.10 EEQ71458.1 - 2.2e-41 140.3 0.1 2.5e-41 140.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Exo_endo_phos_2 PF14529.1 EEQ71459.1 - 1.6e-15 56.7 0.0 5.1e-15 55.1 0.0 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EEQ71459.1 - 7.1e-14 52.3 0.0 6e-13 49.3 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.7 EEQ71459.1 - 0.0011 18.8 0.2 0.0011 18.8 0.1 2.3 2 0 0 2 2 2 1 GRF zinc finger Med12 PF09497.5 EEQ71460.1 - 1.3e-26 92.3 0.1 3.3e-26 91.0 0.1 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 CIA30 PF08547.7 EEQ71461.1 - 4.1e-38 130.6 0.0 2e-25 89.4 0.0 2.1 1 1 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Cation_ATPase_N PF00690.21 EEQ71461.1 - 0.01 15.2 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus SAICAR_synt PF01259.13 EEQ71462.1 - 7.5e-86 287.2 0.0 1.5e-85 286.2 0.0 1.4 1 1 1 2 2 2 2 SAICAR synthetase Apc5 PF12862.2 EEQ71463.1 - 4.1e-36 122.6 6.7 7.2e-36 121.9 3.1 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 EEQ71463.1 - 0.00021 21.1 6.3 1.9 8.5 0.0 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat SUI1 PF01253.17 EEQ71464.1 - 1.9e-29 101.2 5.6 2.5e-29 100.9 3.9 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF520 PF04461.8 EEQ71464.1 - 0.19 11.5 3.4 0.23 11.2 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF520) EOS1 PF12326.3 EEQ71465.1 - 7.6e-12 45.1 1.5 9.3e-12 44.8 1.1 1.1 1 0 0 1 1 1 1 N-glycosylation protein Glyco_hydro_47 PF01532.15 EEQ71466.1 - 7.2e-175 581.9 0.0 8.4e-175 581.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MBA1 PF07961.6 EEQ71467.1 - 7.8e-06 24.9 0.1 2.3e-05 23.3 0.1 1.7 1 1 0 1 1 1 1 MBA1-like protein Tim44 PF04280.10 EEQ71467.1 - 0.0071 16.3 0.6 0.15 12.0 0.1 2.6 2 1 0 2 2 2 1 Tim44-like domain SSF PF00474.12 EEQ71468.1 - 0.39 9.3 23.3 8.3 4.9 16.1 2.6 1 1 0 1 1 1 0 Sodium:solute symporter family IncA PF04156.9 EEQ71468.1 - 1.4 8.4 0.0 1.4 8.4 0.0 3.1 4 0 0 4 4 4 0 IncA protein RhoGAP PF00620.22 EEQ71469.1 - 4.7e-46 156.1 0.0 1e-45 155.0 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EEQ71469.1 - 1.2e-11 44.5 1.1 4e-11 42.9 0.2 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Tropomyosin_1 PF12718.2 EEQ71469.1 - 0.31 10.8 6.1 0.7 9.7 4.2 1.6 1 1 0 1 1 1 0 Tropomyosin like Reo_sigmaC PF04582.7 EEQ71469.1 - 0.36 9.9 1.5 1.7 7.7 0.1 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein RecR PF02132.10 EEQ71470.1 - 1.6 8.2 10.2 0.1 12.0 2.7 2.1 2 0 0 2 2 2 0 RecR protein ABM PF03992.11 EEQ71471.1 - 7.6e-09 35.4 0.0 1.1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Ras PF00071.17 EEQ71473.1 - 4.2e-55 185.5 0.0 4.8e-55 185.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ71473.1 - 2.9e-17 63.2 0.0 4.2e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ71473.1 - 5.2e-09 35.5 0.0 6.4e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RRM_6 PF14259.1 EEQ71474.1 - 6.5e-12 45.2 0.0 1.4e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEQ71474.1 - 1.4e-10 40.6 0.0 1.4e-10 40.6 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CMS1 PF14617.1 EEQ71475.1 - 2.8e-76 255.9 2.6 3.3e-76 255.6 1.8 1.1 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EEQ71475.1 - 0.00017 21.1 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase CENP-T PF15511.1 EEQ71476.1 - 3.2e-100 336.2 14.4 3.2e-100 336.2 10.0 2.3 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 EEQ71476.1 - 4.1e-08 33.3 0.0 7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 EEQ71476.1 - 2.6e-07 30.6 0.0 5.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEQ71476.1 - 0.00077 19.4 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SURF1 PF02104.10 EEQ71477.1 - 6.5e-57 192.7 0.0 9.2e-57 192.2 0.0 1.2 1 0 0 1 1 1 1 SURF1 family UBX PF00789.15 EEQ71478.1 - 2.7e-12 46.5 0.0 5.4e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 UBX domain Hamartin PF04388.7 EEQ71478.1 - 0.051 12.2 5.6 0.069 11.8 3.9 1.2 1 0 0 1 1 1 0 Hamartin protein SOBP PF15279.1 EEQ71478.1 - 2.4 8.4 15.0 4 7.7 10.4 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2076 PF09849.4 EEQ71479.1 - 9.6e-09 35.6 10.2 1.2e-08 35.3 7.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EEQ71479.1 - 1.4e-05 24.8 2.1 2.3e-05 24.1 1.5 1.4 1 0 0 1 1 1 1 CHCH domain VirionAssem_T7 PF11653.3 EEQ71479.1 - 4.2 8.1 5.7 0.68 10.7 0.1 2.1 2 0 0 2 2 2 0 Bacteriophage T7 virion assembly protein Sas10_Utp3 PF04000.10 EEQ71480.1 - 2.9e-19 69.0 0.3 2.9e-19 69.0 0.2 2.0 3 0 0 3 3 3 1 Sas10/Utp3/C1D family MdcE PF06833.6 EEQ71480.1 - 0.033 13.3 0.1 0.064 12.4 0.1 1.4 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) Herpes_DNAp_acc PF04929.7 EEQ71480.1 - 8.9 5.1 12.3 13 4.6 8.5 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor ApbA_C PF08546.6 EEQ71481.1 - 5.4e-31 107.1 0.1 5.4e-31 107.1 0.1 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EEQ71481.1 - 5e-25 87.6 0.0 1.1e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA SET PF00856.23 EEQ71482.1 - 4e-19 69.4 0.0 6.8e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 SET domain E_raikovi_mat PF06360.6 EEQ71483.1 - 3.5 7.8 8.7 29 4.9 6.1 2.2 1 1 0 1 1 1 0 Euplotes raikovi mating pheromone Coq4 PF05019.8 EEQ71484.1 - 1.4e-100 334.7 0.0 1.7e-100 334.5 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 dsDNA_bind PF01984.15 EEQ71485.1 - 1.7e-28 98.7 12.8 2e-28 98.4 8.9 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.1 EEQ71485.1 - 0.01 16.0 0.5 0.01 16.0 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4615) RelB_N PF12910.2 EEQ71485.1 - 0.035 13.4 0.8 0.22 10.9 0.0 2.3 2 0 0 2 2 2 0 Antitoxin of toxin-antitoxin stability system N-terminal DUF1974 PF09317.6 EEQ71485.1 - 0.071 12.5 2.2 0.084 12.2 1.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) Imm35 PF15581.1 EEQ71485.1 - 0.099 12.6 0.2 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 35 PIN_3 PF13470.1 EEQ71485.1 - 0.85 10.2 5.5 1 10.0 0.2 2.1 1 1 1 2 2 2 0 PIN domain FAD_binding_4 PF01565.18 EEQ71486.1 - 5.1e-08 32.4 4.5 1.5e-05 24.4 1.7 2.3 2 0 0 2 2 2 2 FAD binding domain DUF4219 PF13961.1 EEQ71487.1 - 0.056 12.8 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) LIP PF03583.9 EEQ71488.1 - 1.6e-67 227.7 0.0 2.1e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 Secretory lipase Sec2p PF06428.6 EEQ71489.1 - 4e-26 90.7 15.4 4e-26 90.7 10.6 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF3584 PF12128.3 EEQ71489.1 - 0.012 13.0 15.8 0.017 12.4 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 EEQ71489.1 - 3.1 6.1 13.8 5.1 5.4 9.6 1.2 1 0 0 1 1 1 0 AAA domain PRP21_like_P PF12230.3 EEQ71490.1 - 9.4e-60 201.9 20.1 8.2e-59 198.8 13.9 2.0 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EEQ71490.1 - 4.8e-39 131.8 0.9 7.2e-20 70.3 0.0 2.5 2 0 0 2 2 2 2 Surp module UPF0547 PF10571.4 EEQ71490.1 - 0.14 11.9 0.9 0.25 11.0 0.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 PMT PF02366.13 EEQ71491.1 - 2.2e-79 266.3 18.9 2.2e-79 266.3 13.1 2.3 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EEQ71491.1 - 5.5e-55 185.8 0.0 1.1e-54 184.9 0.0 1.5 1 0 0 1 1 1 1 MIR domain B12D PF06522.6 EEQ71492.1 - 0.057 13.1 0.4 0.3 10.8 0.3 2.1 1 1 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit zf-DHHC PF01529.15 EEQ71493.1 - 3.4e-34 117.7 4.7 6.5e-34 116.8 3.2 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase SET PF00856.23 EEQ71494.1 - 5.8e-16 59.2 0.4 5.8e-16 59.2 0.3 4.5 3 2 0 3 3 3 1 SET domain Fungal_trans PF04082.13 EEQ71495.1 - 3.1e-26 91.8 0.4 4.6e-26 91.2 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ71495.1 - 4.2e-07 29.7 9.8 4.2e-07 29.7 6.8 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2360 PF10152.4 EEQ71495.1 - 0.56 10.4 7.5 0.058 13.6 1.0 2.2 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) FGGY_C PF02782.11 EEQ71496.1 - 1.1e-71 240.5 0.7 2.2e-71 239.5 0.5 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EEQ71496.1 - 1.6e-65 220.8 0.0 2.3e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.15 EEQ71497.1 - 2.3e-52 177.6 4.4 3e-52 177.3 3.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein DAO PF01266.19 EEQ71498.1 - 8.8e-48 163.0 0.0 1.3e-47 162.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEQ71498.1 - 9.4e-09 34.6 1.4 2.9e-08 33.0 1.0 1.8 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EEQ71498.1 - 2.1e-06 27.0 0.2 3.6e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEQ71498.1 - 0.00017 21.5 0.5 0.00042 20.2 0.0 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EEQ71498.1 - 0.0014 18.3 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EEQ71498.1 - 0.0022 17.9 0.1 0.0086 16.0 0.1 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EEQ71498.1 - 0.0026 16.8 0.1 0.02 13.9 0.1 2.2 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EEQ71498.1 - 0.013 14.0 0.1 0.029 12.8 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 EEQ71498.1 - 0.024 13.5 0.1 0.082 11.7 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EEQ71498.1 - 0.037 12.9 0.3 0.063 12.1 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 EEQ71498.1 - 0.071 13.5 0.1 0.19 12.1 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEQ71498.1 - 0.091 11.8 0.2 0.21 10.6 0.1 1.5 1 0 0 1 1 1 0 Thi4 family NOA36 PF06524.7 EEQ71499.1 - 0.85 8.8 2.6 1.9 7.6 1.8 1.5 1 0 0 1 1 1 0 NOA36 protein Complex1_LYR_1 PF13232.1 EEQ71500.1 - 2.1e-18 66.2 5.8 2.7e-18 65.9 4.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EEQ71500.1 - 3.5e-16 58.7 5.5 5e-16 58.2 3.8 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 EEQ71500.1 - 0.0091 16.4 1.0 0.011 16.1 0.7 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DUF3629 PF12302.3 EEQ71500.1 - 0.054 12.8 0.2 0.062 12.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) DUF536 PF04394.9 EEQ71501.1 - 0.0052 16.4 2.4 0.0094 15.6 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF536 DUF997 PF06196.7 EEQ71505.1 - 0.14 11.7 0.3 0.23 10.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF997) ADH_N PF08240.7 EEQ71508.1 - 4.6e-10 39.2 0.0 3e-09 36.5 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ71508.1 - 1.2e-06 28.1 0.2 4.1e-06 26.3 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EEQ71508.1 - 0.04 13.9 0.2 0.083 12.8 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding MFS_1 PF07690.11 EEQ71509.1 - 2.5e-28 98.8 50.6 2.5e-28 98.8 35.1 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily ATP-sulfurylase PF01747.12 EEQ71511.1 - 5.3e-86 287.3 0.1 7.3e-86 286.9 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 EEQ71511.1 - 3.6e-57 192.4 0.0 5.5e-57 191.8 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 EEQ71511.1 - 3.2e-53 179.3 0.0 5.6e-53 178.6 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain Phage_Treg PF04761.7 EEQ71511.1 - 0.023 14.4 0.1 0.046 13.4 0.1 1.4 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator UAE_UbL PF14732.1 EEQ71511.1 - 0.096 12.7 0.8 1 9.5 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain CPT PF07931.7 EEQ71511.1 - 0.11 12.1 0.0 0.53 9.8 0.0 2.0 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AA_permease_2 PF13520.1 EEQ71514.1 - 2.6e-49 167.9 34.8 3.5e-49 167.4 24.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ71514.1 - 6.3e-21 74.2 32.9 8.9e-21 73.7 22.8 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_transf_17 PF04724.8 EEQ71515.1 - 1.2e-43 149.5 0.4 4.6e-43 147.5 0.3 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 17 PAPS_reduct PF01507.14 EEQ71517.1 - 6e-41 140.1 0.0 7.8e-41 139.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family CTV_P6 PF06706.6 EEQ71519.1 - 0.11 11.9 0.7 0.22 11.0 0.0 1.8 2 1 0 2 2 2 0 Citrus tristeza virus 6-kDa protein Rhomboid PF01694.17 EEQ71520.1 - 1.2 9.1 8.3 1.5 8.8 5.7 1.1 1 0 0 1 1 1 0 Rhomboid family HAD PF12710.2 EEQ71521.1 - 3.8e-15 56.5 0.1 5.5e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEQ71521.1 - 2.6e-10 41.0 0.2 2.8e-09 37.6 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEQ71521.1 - 6.6e-07 29.1 0.1 4e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EEQ71521.1 - 0.0001 22.5 0.1 0.0003 21.0 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EEQ71521.1 - 0.0022 17.2 0.0 0.049 12.7 0.0 2.0 2 0 0 2 2 2 1 Putative Phosphatase DUF705 PF05152.7 EEQ71521.1 - 0.016 14.2 0.1 0.024 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Radical_SAM PF04055.16 EEQ71522.1 - 8.2e-15 55.3 0.0 1.2e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily adh_short PF00106.20 EEQ71523.1 - 4.1e-15 56.0 0.0 4e-08 33.3 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ71523.1 - 6.2e-07 29.4 0.0 2e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ71523.1 - 0.0023 17.6 0.0 0.09 12.4 0.0 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EEQ71523.1 - 0.025 14.0 0.0 0.073 12.4 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family WD40 PF00400.27 EEQ71525.1 - 2.8e-11 42.8 12.8 1.3e-05 24.8 0.1 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat Gryzun-like PF12742.2 EEQ71525.1 - 0.0037 17.0 0.0 0.0077 16.0 0.0 1.5 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking DUF1513 PF07433.6 EEQ71525.1 - 0.037 12.9 0.1 0.4 9.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) DivIC PF04977.10 EEQ71525.1 - 1.5 8.3 13.9 1.2 8.7 6.8 2.2 1 1 1 2 2 2 0 Septum formation initiator Tox-URI2 PF15653.1 EEQ71525.1 - 2.1 8.6 5.6 2 8.6 2.8 1.8 2 0 0 2 2 2 0 URI fold toxin 2 Gon7 PF08738.5 EEQ71525.1 - 4 7.4 9.4 13 5.8 6.4 2.0 1 1 0 1 1 1 0 Gon7 family Methyltrn_RNA_3 PF02598.12 EEQ71526.1 - 6.1e-83 278.5 0.0 7.5e-83 278.2 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.14 EEQ71526.1 - 0.047 13.5 0.0 8.8 6.1 0.0 2.3 2 0 0 2 2 2 0 SpoU rRNA Methylase family DeoC PF01791.4 EEQ71527.1 - 2e-43 148.3 10.3 3.7e-43 147.5 7.1 1.3 1 1 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.16 EEQ71527.1 - 0.00087 18.3 0.6 0.00087 18.3 0.4 1.7 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase TP_methylase PF00590.15 EEQ71528.1 - 2e-48 164.8 0.3 3.8e-48 163.9 0.1 1.5 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EEQ71528.1 - 8.7e-15 54.8 0.0 1.6e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EEQ71528.1 - 7.8e-10 37.9 0.0 1.7e-06 27.2 0.0 2.7 3 0 0 3 3 3 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EEQ71528.1 - 0.028 13.3 0.0 0.065 12.2 0.0 1.7 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central DUF3958 PF13125.1 EEQ71529.1 - 0.098 12.5 2.8 0.22 11.4 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) PCI PF01399.22 EEQ71530.1 - 9.8e-21 74.0 0.0 3.3e-20 72.3 0.0 1.9 1 0 0 1 1 1 1 PCI domain DUF4376 PF14301.1 EEQ71530.1 - 0.016 15.3 0.9 0.069 13.2 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) Asp_Glu_race_2 PF14669.1 EEQ71530.1 - 0.049 12.9 0.1 0.25 10.6 0.0 2.0 2 0 0 2 2 2 0 Putative aspartate racemase FSH1 PF03959.8 EEQ71531.1 - 1.6e-69 233.6 0.0 2e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EEQ71531.1 - 1.4e-07 31.6 1.2 8.2e-06 25.8 0.9 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ71531.1 - 9.4e-07 28.6 0.0 1.4e-06 28.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EEQ71531.1 - 0.0048 16.2 0.0 0.69 9.1 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EEQ71531.1 - 0.02 14.3 0.0 14 5.0 0.0 2.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.4 EEQ71531.1 - 0.062 12.5 0.0 11 5.2 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase Ribosomal_S27e PF01667.12 EEQ71533.1 - 2.5e-29 100.5 5.9 3.2e-29 100.2 4.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EEQ71533.1 - 0.0053 16.5 1.0 0.0062 16.3 0.7 1.2 1 0 0 1 1 1 1 IBR domain zf-CSL PF05207.8 EEQ71533.1 - 0.12 11.9 0.5 0.22 11.0 0.4 1.5 1 0 0 1 1 1 0 CSL zinc finger CDP-OH_P_transf PF01066.16 EEQ71535.1 - 6.8e-13 48.7 13.9 6.8e-13 48.7 9.7 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF4381 PF14316.1 EEQ71535.1 - 0.038 14.1 0.9 0.088 12.9 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) NIPSNAP PF07978.8 EEQ71536.1 - 1.7e-31 108.2 3.7 7.7e-28 96.4 0.1 3.7 3 1 0 3 3 3 2 NIPSNAP Pyridox_oxidase PF01243.15 EEQ71537.1 - 8.7e-14 51.3 0.0 1.9e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Serpin PF00079.15 EEQ71539.1 - 1e-26 93.9 0.0 4.4e-22 78.7 0.0 2.1 2 0 0 2 2 2 2 Serpin (serine protease inhibitor) Reo_sigmaC PF04582.7 EEQ71540.1 - 0.21 10.7 2.4 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Ycf1 PF05758.7 EEQ71540.1 - 0.6 7.7 14.8 0.77 7.4 10.3 1.1 1 0 0 1 1 1 0 Ycf1 LMBR1 PF04791.11 EEQ71540.1 - 1.1 7.7 9.1 1.5 7.3 6.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3584 PF12128.3 EEQ71540.1 - 4.9 4.3 38.7 0.49 7.6 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Peptidase_C65 PF10275.4 EEQ71541.1 - 1.1e-47 162.5 0.0 2.4e-46 158.0 0.0 2.0 1 1 0 1 1 1 1 Peptidase C65 Otubain Chorismate_synt PF01264.16 EEQ71541.1 - 0.1 11.0 0.0 0.51 8.7 0.0 1.8 2 0 0 2 2 2 0 Chorismate synthase SEO_N PF14576.1 EEQ71541.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Sieve element occlusion N-terminus PCI PF01399.22 EEQ71543.1 - 9.1e-18 64.5 0.1 2.3e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 EEQ71543.1 - 1e-05 25.3 0.1 2.4e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_10 PF13374.1 EEQ71543.1 - 0.00023 20.9 0.1 0.25 11.3 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ71543.1 - 0.0021 17.7 2.6 0.15 11.9 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ71543.1 - 0.0026 17.5 4.1 0.04 13.8 0.1 4.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ71543.1 - 0.011 15.2 2.3 0.076 12.6 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ71543.1 - 0.033 14.1 2.2 0.32 10.9 0.1 3.3 2 2 1 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EEQ71543.1 - 0.038 13.8 0.2 0.14 12.0 0.1 2.0 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Ipi1_N PF12333.3 EEQ71543.1 - 0.039 13.9 0.0 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation CorA PF01544.13 EEQ71543.1 - 0.06 12.3 0.5 0.11 11.4 0.3 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TPR_11 PF13414.1 EEQ71543.1 - 0.17 11.5 1.9 0.48 10.1 0.1 2.8 3 1 0 3 3 3 0 TPR repeat TPR_8 PF13181.1 EEQ71543.1 - 0.18 11.6 0.1 0.18 11.6 0.1 3.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ71543.1 - 0.95 10.2 3.0 6.7 7.6 0.0 3.6 3 1 1 4 4 3 0 Tetratricopeptide repeat CWC25 PF12542.3 EEQ71544.1 - 4.3e-27 94.3 1.4 4.3e-27 94.3 1.0 4.0 4 0 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EEQ71544.1 - 2.6e-12 46.5 14.0 2.6e-12 46.5 9.7 3.7 2 1 1 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR PCEMA1 PF07418.6 EEQ71544.1 - 0.1 11.9 0.1 0.1 11.9 0.1 2.7 2 1 0 2 2 2 0 Acidic phosphoprotein precursor PCEMA1 DUF3674 PF12426.3 EEQ71544.1 - 0.11 11.8 0.2 0.46 9.9 0.1 2.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase DUF605 PF04652.11 EEQ71544.1 - 0.84 8.9 22.8 1.1 8.5 15.8 1.4 1 0 0 1 1 1 0 Vta1 like Ras PF00071.17 EEQ71545.1 - 2.6e-54 182.9 0.0 3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ71545.1 - 4.2e-16 59.5 0.0 5.7e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ71545.1 - 1.3e-09 37.5 0.0 1.9e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEQ71545.1 - 0.00016 20.8 0.0 0.00023 20.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EEQ71545.1 - 0.001 18.3 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EEQ71545.1 - 0.014 15.3 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 EEQ71545.1 - 0.029 13.0 0.0 0.04 12.6 0.0 1.2 1 1 0 1 1 1 0 G-protein alpha subunit PduV-EutP PF10662.4 EEQ71545.1 - 0.045 13.2 0.0 1.4 8.4 0.0 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation VirE PF05272.6 EEQ71545.1 - 0.13 11.6 0.0 3.5 7.0 0.0 2.1 2 0 0 2 2 2 0 Virulence-associated protein E BPL_LplA_LipB PF03099.14 EEQ71546.1 - 1.2e-09 38.2 0.2 6.5e-09 35.8 0.1 2.1 2 1 0 2 2 2 1 Biotin/lipoate A/B protein ligase family Ank_2 PF12796.2 EEQ71547.1 - 5e-24 84.4 1.0 8.2e-09 35.6 0.0 2.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ71547.1 - 2.6e-20 71.1 3.8 3.6e-07 29.6 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EEQ71547.1 - 3e-14 53.0 1.4 4e-05 24.0 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ71547.1 - 1.3e-11 44.3 4.2 2.1e-05 24.5 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ71547.1 - 4.9e-11 41.7 1.1 0.0032 17.5 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Pro_racemase PF05544.6 EEQ71547.1 - 0.15 10.8 0.1 1.4 7.7 0.1 2.0 2 0 0 2 2 2 0 Proline racemase polyprenyl_synt PF00348.12 EEQ71548.1 - 3.5e-52 176.8 0.0 4.6e-49 166.6 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 EEQ71548.1 - 0.017 14.5 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Rpn3_C PF08375.6 EEQ71549.1 - 4.8e-25 87.7 0.2 1.2e-24 86.5 0.1 1.7 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EEQ71549.1 - 2.5e-20 72.7 1.1 1e-19 70.7 0.0 2.4 3 0 0 3 3 3 1 PCI domain Gly-rich_Ago1 PF12764.2 EEQ71549.1 - 0.0029 18.1 0.3 0.0029 18.1 0.2 2.7 3 0 0 3 3 3 1 Glycine-rich region of argonaut PCI_Csn8 PF10075.4 EEQ71549.1 - 0.0087 15.8 0.0 0.071 12.8 0.0 2.2 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 Macoilin PF09726.4 EEQ71549.1 - 1 7.5 10.5 1.5 6.9 7.3 1.1 1 0 0 1 1 1 0 Transmembrane protein DASH_Spc34 PF08657.5 EEQ71550.1 - 2.8e-68 230.4 2.6 1.2e-67 228.3 1.8 1.7 1 1 0 1 1 1 1 DASH complex subunit Spc34 ATG16 PF08614.6 EEQ71550.1 - 0.0013 18.5 1.7 0.012 15.4 0.2 2.2 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DASH_Spc19 PF08287.6 EEQ71550.1 - 0.0087 15.6 2.1 0.016 14.8 1.5 1.4 1 0 0 1 1 1 1 Spc19 SlyX PF04102.7 EEQ71550.1 - 0.051 13.9 2.9 0.45 10.9 0.1 2.5 2 0 0 2 2 2 0 SlyX DUF465 PF04325.8 EEQ71550.1 - 0.057 13.1 0.8 0.057 13.1 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF465) Spectrin PF00435.16 EEQ71550.1 - 0.087 13.1 1.4 12 6.1 0.1 2.4 2 0 0 2 2 2 0 Spectrin repeat Mnd1 PF03962.10 EEQ71550.1 - 0.12 12.0 1.7 0.23 11.1 1.2 1.4 1 0 0 1 1 1 0 Mnd1 family Uds1 PF15456.1 EEQ71550.1 - 0.54 10.2 8.7 0.041 13.8 2.1 2.0 3 0 0 3 3 3 0 Up-regulated During Septation PspB PF06667.7 EEQ71550.1 - 2.2 8.2 6.6 5.3 7.0 1.0 2.4 2 0 0 2 2 2 0 Phage shock protein B IncA PF04156.9 EEQ71550.1 - 3.8 7.0 9.9 28 4.2 7.0 1.9 1 1 0 1 1 1 0 IncA protein TFIID_20kDa PF03847.8 EEQ71551.1 - 2.1e-20 72.7 0.0 4e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Glyco_hydro_18 PF00704.23 EEQ71552.1 - 4e-95 319.1 0.5 4.7e-95 318.9 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EEQ71552.1 - 2.9e-11 43.0 0.0 5.7e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 LysM domain CorA PF01544.13 EEQ71553.1 - 4.3e-15 55.5 0.1 6.4e-15 54.9 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Peptidase_C27 PF05407.7 EEQ71553.1 - 0.093 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Rubella virus endopeptidase TcpE PF12648.2 EEQ71553.1 - 0.58 10.3 2.9 1.1 9.4 2.0 1.3 1 0 0 1 1 1 0 TcpE family NAD_binding_6 PF08030.7 EEQ71554.1 - 1.2e-32 112.9 0.0 2.1e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EEQ71554.1 - 1.1e-20 73.4 0.0 2.8e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EEQ71554.1 - 1e-17 64.4 8.0 1e-17 64.4 5.6 2.3 1 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EEQ71554.1 - 3.5e-05 23.8 0.0 8.4e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EEQ71554.1 - 0.036 14.6 0.0 0.46 11.0 0.0 2.6 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4131 PF13567.1 EEQ71554.1 - 6.8 6.0 7.4 1.5 8.2 1.9 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) eIF2A PF08662.6 EEQ71555.1 - 1.1e-83 279.7 0.1 8.9e-83 276.7 0.0 2.3 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EEQ71555.1 - 3.3e-05 23.6 1.3 1.4 8.9 0.1 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat CDV3 PF15359.1 EEQ71555.1 - 0.013 15.5 1.2 0.013 15.5 0.8 4.0 3 1 2 5 5 5 0 Carnitine deficiency-associated protein 3 Cytochrom_D1 PF02239.11 EEQ71555.1 - 0.07 11.4 0.0 0.21 9.8 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain BTB PF00651.26 EEQ71556.1 - 3e-05 23.9 0.0 6.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain malic PF00390.14 EEQ71558.1 - 4.8e-10 39.3 0.0 3.1e-09 36.6 0.0 2.1 1 1 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.10 EEQ71558.1 - 1.9e-09 37.4 0.2 2.6e-09 37.0 0.1 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain Collagen PF01391.13 EEQ71558.1 - 0.16 11.5 1.6 0.47 10.0 1.1 1.8 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Acetyltransf_13 PF13880.1 EEQ71560.1 - 1.5e-28 98.2 0.0 4.8e-28 96.7 0.0 1.9 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EEQ71560.1 - 4.6e-17 61.2 0.1 1.2e-16 59.9 0.1 1.8 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Glyoxalase_2 PF12681.2 EEQ71562.1 - 1.2e-08 35.5 0.0 2.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase-like domain Gly-zipper_Omp PF13488.1 EEQ71562.1 - 0.028 14.0 1.8 0.056 13.0 1.3 1.4 1 0 0 1 1 1 0 Glycine zipper Glyoxalase PF00903.20 EEQ71562.1 - 0.086 12.8 0.0 0.086 12.8 0.0 2.0 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily EMG1 PF03587.9 EEQ71563.1 - 3.9e-78 261.3 0.0 4.6e-78 261.1 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase UQ_con PF00179.21 EEQ71564.1 - 1.1e-50 170.7 0.0 1.2e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEQ71564.1 - 9.1e-05 22.2 0.0 0.00011 22.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEQ71564.1 - 0.0088 15.9 0.0 0.0096 15.8 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EEQ71564.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain XPG_I PF00867.13 EEQ71568.1 - 3.9e-30 103.7 0.8 7.4e-30 102.8 0.0 1.9 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 EEQ71568.1 - 6.6e-23 80.8 1.1 3.9e-22 78.4 0.0 2.7 2 2 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 EEQ71568.1 - 4.8e-06 26.7 0.5 3.2e-05 24.1 0.0 2.5 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HXXSHH PF07586.6 EEQ71568.1 - 0.079 11.8 2.7 0.29 10.0 2.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) AMP-binding PF00501.23 EEQ71569.1 - 4.2e-76 256.0 0.0 5.3e-76 255.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ71569.1 - 2.3e-15 57.3 0.1 1e-14 55.1 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PDZ_1 PF12812.2 EEQ71569.1 - 0.11 12.3 0.0 0.34 10.8 0.0 1.8 1 0 0 1 1 1 0 PDZ-like domain Fungal_trans_2 PF11951.3 EEQ71570.1 - 1.4e-35 122.6 3.3 1.9e-35 122.1 2.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ71570.1 - 7.4e-08 32.1 9.9 7.4e-08 32.1 6.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_3 PF00202.16 EEQ71571.1 - 5.4e-76 255.6 0.1 6.3e-76 255.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III MCP_N PF05581.7 EEQ71571.1 - 0.13 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Vibrio chemotaxis protein N terminus adh_short PF00106.20 EEQ71572.1 - 1.5e-22 80.2 0.1 4.6e-22 78.7 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ71572.1 - 2.2e-15 57.1 0.0 1e-14 54.9 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ71572.1 - 9.3e-10 38.4 0.0 1.3e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.11 EEQ71573.1 - 6.7e-21 74.3 46.6 1.9e-10 39.9 12.4 3.1 1 1 1 3 3 3 3 Major Facilitator Superfamily 7TM_GPCR_Srab PF10292.4 EEQ71573.1 - 0.045 12.4 0.2 0.079 11.6 0.2 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor GMC_oxred_N PF00732.14 EEQ71576.1 - 9e-36 123.5 0.0 1.8e-35 122.5 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EEQ71576.1 - 9e-32 110.3 0.0 2.8e-31 108.7 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EEQ71576.1 - 5e-06 25.6 0.0 8.5e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EEQ71576.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Linker_histone PF00538.14 EEQ71578.1 - 1.5e-23 82.6 0.1 2.7e-23 81.8 0.1 1.4 1 0 0 1 1 1 1 linker histone H1 and H5 family DUF572 PF04502.8 EEQ71578.1 - 2.1 7.5 12.7 2.6 7.1 8.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Herpes_BLLF1 PF05109.8 EEQ71578.1 - 5.2 4.8 17.8 4.9 4.9 12.3 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) SRP-alpha_N PF04086.8 EEQ71578.1 - 5.3 6.3 19.2 7.3 5.8 13.3 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PIP5K PF01504.13 EEQ71580.1 - 1.1e-85 286.8 0.7 1.3e-85 286.5 0.0 1.5 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase WD40 PF00400.27 EEQ71581.1 - 1.7 8.6 5.5 12 6.0 0.1 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat Apc1 PF12859.2 EEQ71582.1 - 2.4e-28 98.4 0.8 1.7e-27 95.7 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EEQ71582.1 - 8.5e-07 28.8 6.7 0.0021 18.1 0.0 4.6 4 0 0 4 4 4 3 Proteasome/cyclosome repeat Fungal_trans_2 PF11951.3 EEQ71583.1 - 7.7e-31 107.0 2.3 2.2e-21 75.8 0.4 2.5 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ71583.1 - 2.1e-08 33.9 7.3 4e-08 33.0 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu-oxidase_3 PF07732.10 EEQ71584.1 - 1.1e-43 147.7 0.3 1.4e-40 137.6 0.0 3.2 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EEQ71584.1 - 1.5e-33 115.2 2.1 1.5e-33 115.2 1.4 4.0 2 2 2 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.17 EEQ71584.1 - 1.1e-15 57.8 0.0 1.2e-13 51.2 0.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase Phosphoesterase PF04185.9 EEQ71585.1 - 8.1e-72 242.4 0.8 8.1e-72 242.4 0.6 2.0 2 0 0 2 2 2 2 Phosphoesterase family Sugar_tr PF00083.19 EEQ71586.1 - 4e-35 121.2 1.8 7.8e-35 120.3 1.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ71586.1 - 9e-10 37.7 7.3 1.8e-09 36.8 5.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 EEQ71587.1 - 4.9e-37 127.4 49.1 5.6e-34 117.4 33.0 3.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Trp_halogenase PF04820.9 EEQ71587.1 - 0.14 10.7 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase PALP PF00291.20 EEQ71588.1 - 9.2e-28 97.3 0.0 1.6e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.15 EEQ71588.1 - 1.2e-11 44.9 0.0 6.4e-11 42.5 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Thionin PF00321.12 EEQ71590.1 - 0.04 14.1 12.8 0.95 9.7 0.4 4.2 3 0 0 3 3 3 0 Plant thionin HUN PF08729.5 EEQ71591.1 - 6.8e-15 54.6 0.0 1.5e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain FNIP_N PF14636.1 EEQ71592.1 - 0.08 13.4 0.5 0.14 12.6 0.3 1.4 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus RPAP1_C PF08620.5 EEQ71593.1 - 9.7e-29 99.0 0.0 2e-28 98.0 0.0 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EEQ71593.1 - 6.5e-14 51.2 6.9 1.2e-13 50.3 4.8 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal AMP-binding PF00501.23 EEQ71594.1 - 5.5e-82 275.3 0.0 6.9e-82 275.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ71594.1 - 1.9e-10 41.5 0.0 5.9e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ABC2_membrane PF01061.19 EEQ71596.1 - 1.7e-69 233.2 62.8 5.1e-40 136.8 17.1 3.2 3 1 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EEQ71596.1 - 6.3e-39 133.4 0.0 1e-17 64.7 0.0 3.5 4 0 0 4 4 4 2 ABC transporter PDR_CDR PF06422.7 EEQ71596.1 - 6.9e-29 99.5 12.8 2.5e-25 88.1 0.0 4.3 4 0 0 4 4 4 2 CDR ABC transporter ABC_trans_N PF14510.1 EEQ71596.1 - 6.1e-18 64.6 0.0 2.7e-17 62.6 0.0 2.2 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EEQ71596.1 - 7.1e-10 38.5 0.0 4e-06 26.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 EEQ71596.1 - 2e-06 27.2 0.4 0.0012 18.2 0.0 3.3 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_33 PF13671.1 EEQ71596.1 - 4e-06 26.7 0.1 0.017 14.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EEQ71596.1 - 5.6e-06 26.4 0.3 0.00028 20.9 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_21 PF13304.1 EEQ71596.1 - 1e-05 25.6 0.0 0.071 13.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain ABC2_membrane_3 PF12698.2 EEQ71596.1 - 2.2e-05 23.6 15.2 2.2e-05 23.6 10.5 3.1 2 1 1 3 3 2 1 ABC-2 family transporter protein DUF258 PF03193.11 EEQ71596.1 - 2.9e-05 23.3 0.0 0.0039 16.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 EEQ71596.1 - 4.5e-05 22.9 0.4 0.00089 18.7 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EEQ71596.1 - 0.00016 22.4 0.0 0.023 15.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EEQ71596.1 - 0.00081 19.0 0.3 0.15 11.6 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EEQ71596.1 - 0.00085 19.4 0.1 0.25 11.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 EEQ71596.1 - 0.001 18.3 0.1 1.5 8.0 0.0 3.4 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EEQ71596.1 - 0.0027 17.9 0.0 0.033 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EEQ71596.1 - 0.0083 16.6 0.0 4.4 7.8 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein UPF0079 PF02367.12 EEQ71596.1 - 0.0085 15.7 0.3 0.47 10.0 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EEQ71596.1 - 0.0098 15.3 0.0 1.8 7.9 0.0 3.0 3 0 0 3 3 3 1 AAA-like domain RNA_helicase PF00910.17 EEQ71596.1 - 0.019 15.1 0.0 6.9 6.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.1 EEQ71596.1 - 0.02 14.6 0.1 4.4 7.1 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 EEQ71596.1 - 0.021 14.3 0.1 4.3 6.7 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EEQ71596.1 - 0.035 14.0 0.0 11 6.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Pax2_C PF12403.3 EEQ71596.1 - 0.047 13.3 0.4 0.19 11.3 0.2 2.0 2 0 0 2 2 2 0 Paired-box protein 2 C terminal AAA_23 PF13476.1 EEQ71596.1 - 0.05 13.9 0.3 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EEQ71596.1 - 0.053 13.7 0.1 2.5 8.3 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EEQ71596.1 - 0.078 12.9 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EEQ71596.1 - 0.14 11.6 0.1 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EEQ71596.1 - 0.16 11.4 0.2 14 5.0 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 EEQ71596.1 - 0.23 10.2 0.3 13 4.5 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_15 PF13175.1 EEQ71596.1 - 0.37 9.7 0.0 3.6 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Acetyltransf_1 PF00583.19 EEQ71597.1 - 3.1e-07 30.3 0.0 5e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EEQ71597.1 - 2.9e-06 27.4 0.0 0.00016 21.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEQ71597.1 - 6.4e-06 26.2 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEQ71597.1 - 0.00033 20.5 0.0 0.00052 19.8 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EEQ71597.1 - 0.00045 20.0 0.0 0.65 9.8 0.0 2.6 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ71597.1 - 0.015 15.0 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Plasmodium_Vir PF05795.6 EEQ71598.1 - 0.069 12.3 0.2 0.13 11.4 0.1 1.5 1 1 0 1 1 1 0 Plasmodium vivax Vir protein VIT PF08487.5 EEQ71599.1 - 0.019 14.6 0.1 0.026 14.2 0.1 1.2 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain Neuromodulin_N PF10580.4 EEQ71599.1 - 0.048 13.3 0.4 0.11 12.1 0.3 1.6 1 0 0 1 1 1 0 Gap junction protein N-terminal region DUF4405 PF14358.1 EEQ71600.1 - 0.19 11.8 1.1 0.27 11.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) Chs3p PF12271.3 EEQ71601.1 - 1.8e-141 470.3 15.8 2e-141 470.1 11.0 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Abhydrolase_5 PF12695.2 EEQ71602.1 - 1.7e-05 24.5 0.4 5.3e-05 22.9 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EEQ71602.1 - 0.00018 20.9 0.0 0.00032 20.0 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EEQ71602.1 - 0.0023 17.5 0.1 0.0052 16.3 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EEQ71602.1 - 0.0063 16.4 3.8 0.02 14.7 2.6 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1459 PF07312.6 EEQ71602.1 - 0.0087 15.9 0.2 7.5 6.5 0.8 2.9 1 1 1 2 2 2 2 Protein of unknown function (DUF1459) LCAT PF02450.10 EEQ71602.1 - 0.011 14.7 0.1 0.041 12.8 0.0 1.7 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase DUF915 PF06028.6 EEQ71602.1 - 0.057 12.5 0.0 5.9 5.8 0.0 2.7 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) 4HBT_3 PF13622.1 EEQ71603.1 - 5.3e-43 147.6 0.1 5.3e-43 147.6 0.0 1.4 2 0 0 2 2 2 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EEQ71603.1 - 4.1e-10 39.4 3.0 7.6e-06 25.5 1.7 3.3 2 1 0 2 2 2 2 Acyl-CoA thioesterase YCII PF03795.9 EEQ71604.1 - 1.1e-08 35.1 0.0 1.7e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain Cyclin PF08613.6 EEQ71605.1 - 2.5e-06 27.9 0.1 9.9e-06 26.0 0.0 1.9 1 1 1 2 2 2 1 Cyclin v110 PF01639.12 EEQ71607.1 - 0.033 13.7 2.0 0.05 13.1 1.4 1.3 1 0 0 1 1 1 0 Viral family 110 Pyr_redox_2 PF07992.9 EEQ71609.1 - 8.3e-27 94.3 0.1 3.2e-16 59.8 0.0 3.3 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEQ71609.1 - 2.6e-12 46.9 0.0 1.2e-10 41.6 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEQ71609.1 - 0.0006 19.9 1.4 1.2 9.0 0.3 3.7 3 1 1 5 5 5 3 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L18e PF00828.14 EEQ71610.1 - 4.3e-05 23.8 6.5 0.0011 19.3 0.7 2.4 2 0 0 2 2 2 2 Ribosomal protein L18e/L15 Pkinase PF00069.20 EEQ71611.1 - 1.3e-47 162.0 0.0 1.8e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ71611.1 - 1.8e-25 89.5 0.0 2.6e-24 85.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase SH3_1 PF00018.23 EEQ71612.1 - 0.00028 20.1 0.0 0.00058 19.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain NST1 PF13945.1 EEQ71613.1 - 0.0044 17.1 11.7 0.0062 16.6 8.1 1.3 1 0 0 1 1 1 1 Salt tolerance down-regulator Sec62 PF03839.11 EEQ71613.1 - 0.0048 16.3 8.6 0.0051 16.2 6.0 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 SR-25 PF10500.4 EEQ71613.1 - 0.0048 16.3 19.4 0.0054 16.2 13.5 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Rtf2 PF04641.7 EEQ71613.1 - 0.011 14.9 11.5 0.011 14.9 8.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Myb_Cef PF11831.3 EEQ71613.1 - 0.016 14.4 5.8 0.017 14.3 4.0 1.1 1 0 0 1 1 1 0 pre-mRNA splicing factor component GAGA_bind PF06217.7 EEQ71613.1 - 0.041 13.8 8.6 0.036 14.0 6.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family 7tm_1 PF00001.16 EEQ71613.1 - 0.076 12.1 0.7 0.088 11.9 0.5 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) RPOL_N PF14700.1 EEQ71613.1 - 0.089 12.0 6.8 0.1 11.8 4.7 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Atrophin-1 PF03154.10 EEQ71613.1 - 0.094 10.8 8.5 0.087 10.9 5.9 1.1 1 0 0 1 1 1 0 Atrophin-1 family YqfQ PF14181.1 EEQ71613.1 - 0.21 11.5 14.2 0.24 11.4 9.8 1.2 1 0 0 1 1 1 0 YqfQ-like protein ATP11 PF06644.6 EEQ71613.1 - 0.26 10.7 11.1 0.27 10.7 7.7 1.1 1 0 0 1 1 1 0 ATP11 protein Glyco_transf_15 PF01793.11 EEQ71613.1 - 0.3 9.9 6.6 0.31 9.9 4.6 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Tim54 PF11711.3 EEQ71613.1 - 0.31 9.6 7.4 0.32 9.5 5.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.7 EEQ71613.1 - 0.33 10.8 15.7 0.35 10.7 10.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.3 EEQ71613.1 - 0.33 9.6 13.9 0.34 9.6 9.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Tom37_C PF11801.3 EEQ71613.1 - 0.36 10.6 5.1 0.37 10.6 3.5 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain Btz PF09405.5 EEQ71613.1 - 0.58 10.2 9.1 0.78 9.7 6.3 1.1 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding EssA PF10661.4 EEQ71613.1 - 0.7 9.5 13.9 0.89 9.2 9.6 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF2413 PF10310.4 EEQ71613.1 - 0.72 8.6 10.4 0.71 8.6 7.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) OATP PF03137.15 EEQ71613.1 - 0.85 7.5 4.6 0.87 7.5 3.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF3987 PF13148.1 EEQ71613.1 - 1.3 7.4 11.6 1.5 7.2 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Vfa1 PF08432.5 EEQ71613.1 - 1.4 8.8 20.3 1.7 8.6 14.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GCD14 PF08704.5 EEQ71613.1 - 1.5 8.2 3.8 1.5 8.2 2.6 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF106 PF01956.11 EEQ71613.1 - 1.7 8.1 7.1 1.7 8.1 4.9 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 SpoVR PF04293.8 EEQ71613.1 - 3.6 5.8 7.0 3.9 5.7 4.8 1.0 1 0 0 1 1 1 0 SpoVR like protein DUF3807 PF12720.2 EEQ71613.1 - 3.9 7.6 12.7 4.3 7.4 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) AIF_C PF14721.1 EEQ71613.1 - 4 7.6 6.5 4.8 7.4 4.5 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CDC45 PF02724.9 EEQ71613.1 - 5.3 4.9 8.0 6.1 4.7 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Folate_carrier PF01770.13 EEQ71613.1 - 5.9 5.2 5.6 6.1 5.2 3.9 1.1 1 0 0 1 1 1 0 Reduced folate carrier Peptidase_S49_N PF08496.5 EEQ71613.1 - 6.5 6.5 20.1 10 5.8 13.9 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3464 PF11947.3 EEQ71613.1 - 6.7 6.1 14.1 8.3 5.8 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF2828 PF11443.3 EEQ71613.1 - 8.9 4.3 11.4 9.7 4.2 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF1168 PF06658.7 EEQ71613.1 - 9 5.8 28.3 12 5.4 19.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) ABC_tran PF00005.22 EEQ71614.1 - 4.7e-49 166.1 0.0 1.6e-25 90.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EEQ71614.1 - 1.4e-22 81.0 0.0 1.8e-05 24.8 0.0 4.3 3 1 1 4 4 4 4 AAA domain ABC2_membrane_3 PF12698.2 EEQ71614.1 - 4.7e-21 75.1 43.9 5.1e-14 52.0 16.3 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.1 EEQ71614.1 - 3.3e-10 39.3 2.4 2.5e-05 23.7 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EEQ71614.1 - 3.3e-08 33.0 0.1 0.039 13.1 0.0 3.9 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EEQ71614.1 - 5.5e-08 33.3 0.3 0.0068 16.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EEQ71614.1 - 6.1e-05 22.2 0.1 0.36 10.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EEQ71614.1 - 9.9e-05 22.4 0.1 0.33 10.9 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.1 EEQ71614.1 - 0.00039 19.5 0.0 1.8 7.5 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EEQ71614.1 - 0.00091 19.3 0.1 2.1 8.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEQ71614.1 - 0.0012 18.3 0.0 0.47 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain MutS_V PF00488.16 EEQ71614.1 - 0.0027 17.1 0.1 1.8 7.9 0.0 2.9 3 0 0 3 3 3 1 MutS domain V RNA_helicase PF00910.17 EEQ71614.1 - 0.005 17.0 0.0 0.37 10.9 0.0 2.5 2 0 0 2 2 2 1 RNA helicase SbcCD_C PF13558.1 EEQ71614.1 - 0.0063 16.3 0.1 11 6.0 0.0 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EEQ71614.1 - 0.0071 16.2 0.9 15 5.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.1 EEQ71614.1 - 0.0072 15.9 0.1 1 8.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 EEQ71614.1 - 0.013 15.0 0.1 0.95 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_28 PF13521.1 EEQ71614.1 - 0.027 14.4 0.0 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EEQ71614.1 - 0.042 12.9 0.1 9.4 5.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 EEQ71614.1 - 0.081 12.6 1.4 1.6 8.5 0.0 2.9 3 0 0 3 3 2 0 Part of AAA domain AAA PF00004.24 EEQ71614.1 - 0.088 13.0 0.0 16 5.6 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EEQ71614.1 - 0.13 11.4 0.1 48 3.0 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 EEQ71614.1 - 0.13 11.7 0.0 0.78 9.1 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family SRP54 PF00448.17 EEQ71614.1 - 0.15 11.4 0.1 5.4 6.4 0.1 2.5 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.18 EEQ71614.1 - 0.17 11.8 0.0 27 4.7 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase G-alpha PF00503.15 EEQ71614.1 - 0.21 10.2 0.0 4 6.0 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Fungal_trans PF04082.13 EEQ71615.1 - 0.046 12.5 0.2 0.086 11.7 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain SWIRM PF04433.12 EEQ71617.1 - 1.7e-14 53.7 0.0 3e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain CDC50 PF03381.10 EEQ71618.1 - 1.1e-98 329.8 0.0 1.4e-98 329.4 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF4282 PF14110.1 EEQ71618.1 - 0.044 13.9 0.9 3.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) SPT16 PF08644.6 EEQ71619.1 - 5.1e-61 204.9 0.0 1.6e-60 203.3 0.0 1.9 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EEQ71619.1 - 1.3e-55 187.3 0.1 4.3e-55 185.6 0.0 2.0 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EEQ71619.1 - 8.4e-23 81.0 0.0 1.5e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EEQ71619.1 - 4e-21 74.7 0.0 1.3e-20 73.1 0.0 2.0 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Mito_carr PF00153.22 EEQ71620.1 - 2.8e-20 71.8 1.1 2.5e-13 49.5 0.0 3.6 4 0 0 4 4 4 2 Mitochondrial carrier protein Sugar_tr PF00083.19 EEQ71621.1 - 8.4e-99 331.1 17.0 1e-98 330.8 11.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ71621.1 - 1.2e-24 86.6 43.9 1.4e-23 83.2 15.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EEQ71621.1 - 0.035 13.9 1.0 0.099 12.4 0.1 2.1 2 0 0 2 2 2 0 MFS_1 like family Tmemb_18A PF09771.4 EEQ71621.1 - 0.24 11.3 1.4 3.7 7.5 0.0 3.0 3 1 1 4 4 4 0 Transmembrane protein 188 PMT PF02366.13 EEQ71622.1 - 2.7e-83 279.1 16.5 2.7e-83 279.1 11.4 2.6 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EEQ71622.1 - 6e-38 130.2 1.1 8.1e-38 129.8 0.8 1.2 1 0 0 1 1 1 1 MIR domain Ras PF00071.17 EEQ71623.1 - 3.7e-46 156.4 0.0 2.9e-35 121.0 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EEQ71623.1 - 3e-16 59.9 0.0 4.7e-11 43.2 0.0 2.2 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 EEQ71623.1 - 3.6e-07 29.5 0.0 1.4e-06 27.6 0.0 1.9 2 1 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEQ71623.1 - 1.3e-06 27.9 0.0 2.8e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EEQ71623.1 - 0.00039 19.6 0.0 0.0023 17.1 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEQ71623.1 - 0.0032 17.3 0.0 0.02 14.8 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Cut8_N PF14482.1 EEQ71623.1 - 0.035 14.0 4.8 0.075 13.0 3.4 1.5 1 0 0 1 1 1 0 Cut8 proteasome-binding domain TAT_signal PF10518.4 EEQ71623.1 - 0.039 13.9 1.3 0.16 12.0 0.9 2.1 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence AAA_22 PF13401.1 EEQ71623.1 - 0.049 13.7 0.0 0.53 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EEQ71623.1 - 0.074 12.4 0.0 12 5.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AflR PF08493.5 EEQ71623.1 - 1.3 8.0 11.4 2 7.3 7.9 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein Choline_transpo PF04515.7 EEQ71624.1 - 8.2e-09 34.6 19.9 8.2e-09 34.6 13.8 2.3 3 0 0 3 3 3 2 Plasma-membrane choline transporter Aldo_ket_red PF00248.16 EEQ71627.1 - 4.1e-47 160.3 0.0 4.7e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.9 EEQ71628.1 - 2.7e-122 408.5 0.0 3.4e-122 408.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family UIM PF02809.15 EEQ71629.1 - 0.046 13.2 0.9 0.046 13.2 0.6 3.7 4 0 0 4 4 4 0 Ubiquitin interaction motif RBB1NT PF08169.6 EEQ71629.1 - 0.14 12.0 0.0 16 5.5 0.0 2.4 2 0 0 2 2 2 0 RBB1NT (NUC162) domain zf-CCHC PF00098.18 EEQ71630.1 - 8.7e-53 173.8 58.6 4.8e-09 35.7 1.0 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EEQ71630.1 - 1.3e-12 47.1 43.8 0.037 13.6 0.4 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 EEQ71630.1 - 0.00049 19.7 53.0 0.068 12.9 0.7 6.9 3 2 3 6 6 6 4 Zinc knuckle zf-CCHC_6 PF15288.1 EEQ71630.1 - 0.0034 17.0 46.2 0.053 13.1 0.7 6.9 5 2 2 7 7 7 4 Zinc knuckle zf-CCHC_2 PF13696.1 EEQ71630.1 - 0.22 11.0 40.6 0.77 9.3 0.2 7.0 3 2 4 7 7 7 0 Zinc knuckle F-box PF00646.28 EEQ71631.1 - 5.9e-07 28.9 0.1 1.7e-06 27.5 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EEQ71631.1 - 2e-06 27.4 0.1 4.4e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 EEQ71631.1 - 1.3e-05 24.8 1.3 0.037 13.9 0.1 3.7 3 1 0 3 3 3 2 WD domain, G-beta repeat SAE2 PF08573.5 EEQ71632.1 - 5.2e-31 107.1 1.5 1.4e-30 105.7 0.0 2.5 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus TBPIP PF07106.8 EEQ71632.1 - 0.017 14.6 3.7 0.034 13.6 1.2 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_MLP1_2 PF07926.7 EEQ71632.1 - 0.12 12.1 8.0 2.7 7.7 3.0 2.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spc24 PF08286.6 EEQ71632.1 - 0.19 11.4 3.1 0.43 10.2 2.1 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF972 PF06156.8 EEQ71632.1 - 0.4 11.0 9.4 0.15 12.4 2.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DivIC PF04977.10 EEQ71632.1 - 0.92 9.0 4.7 1.3 8.5 1.7 2.3 2 0 0 2 2 2 0 Septum formation initiator Mnd1 PF03962.10 EEQ71632.1 - 1.1 8.8 7.0 0.62 9.6 2.5 2.2 2 0 0 2 2 2 0 Mnd1 family bZIP_1 PF00170.16 EEQ71632.1 - 9.8 6.2 12.6 4.2 7.3 0.8 3.2 3 0 0 3 3 3 0 bZIP transcription factor Pex16 PF08610.5 EEQ71633.1 - 1.2e-115 386.1 0.8 1.5e-115 385.8 0.6 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) RNase_HII PF01351.13 EEQ71634.1 - 2.7e-47 160.9 0.0 4.8e-47 160.1 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease HII Mif2_N PF15624.1 EEQ71635.1 - 1.1e-39 136.1 2.2 1.1e-39 136.1 1.5 4.2 3 1 1 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.3 EEQ71635.1 - 5.6e-35 119.1 1.2 1e-34 118.3 0.9 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 EEQ71635.1 - 1.1e-06 28.0 0.0 2.5e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Myb_DNA-binding PF00249.26 EEQ71638.1 - 4.7e-11 42.5 1.5 2e-08 34.1 0.1 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEQ71638.1 - 7.3e-09 35.6 0.2 1.1e-05 25.4 0.0 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF4588 PF15251.1 EEQ71638.1 - 0.065 13.1 0.1 0.065 13.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4588) Methyltransf_11 PF08241.7 EEQ71639.1 - 1.8e-10 41.1 0.0 3.3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ71639.1 - 2.9e-09 36.8 0.0 5.4e-09 35.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ71639.1 - 0.00027 21.3 0.0 0.00054 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ71639.1 - 0.0015 18.8 0.0 0.0031 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ71639.1 - 0.0031 18.0 0.0 0.0057 17.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain NinE PF05322.6 EEQ71639.1 - 0.059 13.1 0.0 3.1 7.6 0.0 2.2 2 0 0 2 2 2 0 NINE Protein Methyltransf_31 PF13847.1 EEQ71639.1 - 0.091 12.3 0.1 0.28 10.7 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain CAP_GLY PF01302.20 EEQ71640.1 - 4.4e-28 96.7 0.0 7.1e-28 96.1 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EEQ71640.1 - 9.2e-16 57.8 0.0 1.8e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EEQ71640.1 - 1.7e-06 27.2 0.7 6.7e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family Nucleoplasmin PF03066.10 EEQ71640.1 - 0.012 15.1 0.5 0.019 14.4 0.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin Myc_N PF01056.13 EEQ71640.1 - 0.066 12.3 0.2 0.097 11.8 0.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region AF1Q PF15017.1 EEQ71640.1 - 0.082 12.8 2.4 0.2 11.5 1.7 1.6 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator CENP-B_dimeris PF09026.5 EEQ71640.1 - 0.24 11.6 3.6 0.56 10.4 2.5 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ribosomal_60s PF00428.14 EEQ71640.1 - 0.35 11.2 6.5 0.87 10.0 4.5 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein AMP-binding PF00501.23 EEQ71641.1 - 3.7e-74 249.5 0.0 9.6e-74 248.2 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EEQ71641.1 - 4e-68 229.0 0.0 6.6e-68 228.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EEQ71641.1 - 5.9e-12 45.5 0.0 1.1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EEQ71641.1 - 9e-12 45.0 0.0 1.9e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEQ71641.1 - 1.1e-09 39.0 0.0 8.2e-09 36.2 0.0 2.6 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 EEQ71641.1 - 1.1e-08 34.1 0.0 2.5e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EEQ71641.1 - 0.023 13.5 0.0 0.5 9.2 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EEQ71641.1 - 0.19 10.5 0.0 0.43 9.4 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SWIM PF04434.12 EEQ71643.1 - 0.081 12.4 2.9 0.79 9.2 0.1 2.3 2 0 0 2 2 2 0 SWIM zinc finger MitMem_reg PF13012.1 EEQ71644.1 - 1.4e-39 134.7 0.6 2.7e-39 133.8 0.2 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EEQ71644.1 - 1.5e-27 95.5 0.0 4.1e-27 94.1 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF1183 PF06682.7 EEQ71644.1 - 0.052 13.1 2.1 0.069 12.7 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) ADK PF00406.17 EEQ71645.1 - 2.1e-60 202.9 0.0 2.8e-60 202.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EEQ71645.1 - 2.2e-14 52.8 0.0 5.6e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EEQ71645.1 - 5e-05 23.2 0.0 8.6e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEQ71645.1 - 0.00044 21.0 0.0 0.00089 20.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEQ71645.1 - 0.0018 17.3 0.0 0.0033 16.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EEQ71645.1 - 0.0035 17.6 0.0 0.007 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EEQ71645.1 - 0.034 13.5 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase GFO_IDH_MocA PF01408.17 EEQ71647.1 - 7.2e-17 62.0 0.1 1.2e-16 61.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold zf-CCHC_4 PF14392.1 EEQ71648.1 - 0.00058 19.4 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Zinc knuckle CTD_bind PF04818.8 EEQ71648.1 - 0.00076 19.6 0.0 0.0024 18.1 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.3 EEQ71648.1 - 0.0012 18.9 0.2 0.0035 17.4 0.1 1.8 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 VHS PF00790.14 EEQ71648.1 - 0.0075 15.9 0.1 0.025 14.1 0.0 1.9 2 0 0 2 2 2 1 VHS domain zf-ISL3 PF14690.1 EEQ71648.1 - 0.018 15.0 3.3 0.038 14.0 1.3 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2HC_2 PF13913.1 EEQ71648.1 - 0.33 10.6 5.6 3.3 7.4 0.1 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type RRN7 PF11781.3 EEQ71648.1 - 0.37 10.3 1.6 1.9 8.0 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_6 PF13912.1 EEQ71648.1 - 1 9.3 3.8 10 6.1 0.9 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger HOOK PF05622.7 EEQ71650.1 - 2.1e-24 85.3 26.5 2.1e-24 85.3 18.4 3.4 2 1 0 2 2 2 1 HOOK protein BLOC1_2 PF10046.4 EEQ71650.1 - 0.0081 16.2 0.6 0.0081 16.2 0.4 7.1 3 2 3 8 8 8 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1548 PF07579.6 EEQ71650.1 - 0.018 15.1 0.6 0.018 15.1 0.4 3.2 3 1 1 4 4 4 0 Domain of Unknown Function (DUF1548) Reo_sigmaC PF04582.7 EEQ71650.1 - 0.28 10.3 21.2 0.07 12.3 2.2 4.0 2 2 4 6 6 6 0 Reovirus sigma C capsid protein Sec8_exocyst PF04048.9 EEQ71650.1 - 3.7 7.1 35.9 0.03 13.9 0.9 6.2 3 2 3 6 6 6 0 Sec8 exocyst complex component specific domain Coprogen_oxidas PF01218.13 EEQ71651.1 - 1.2e-120 401.5 0.5 6.3e-118 392.6 0.1 2.4 2 1 0 2 2 2 1 Coproporphyrinogen III oxidase Atg8 PF02991.11 EEQ71652.1 - 3.8e-51 171.3 0.2 4.4e-51 171.1 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EEQ71652.1 - 2.5e-06 27.5 0.0 3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF2665 PF11654.3 EEQ71653.1 - 1.5e-06 27.6 0.0 3.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) Mito_carr PF00153.22 EEQ71654.1 - 5e-27 93.4 0.4 4.9e-15 55.0 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Apc15p PF05841.6 EEQ71656.1 - 6.7e-28 97.9 2.5 6.7e-28 97.9 1.7 2.2 2 0 0 2 2 2 1 Apc15p protein SNARE PF05739.14 EEQ71657.1 - 1.2e-09 37.7 1.5 1.7e-09 37.2 1.1 1.2 1 0 0 1 1 1 1 SNARE domain Caprin-1_C PF12287.3 EEQ71657.1 - 0.32 10.3 2.9 0.39 10.0 2.0 1.2 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term CHZ PF09649.5 EEQ71658.1 - 2.2e-16 58.8 2.9 2.2e-16 58.8 2.0 1.9 2 1 0 2 2 2 1 Histone chaperone domain CHZ PGA2 PF07543.7 EEQ71658.1 - 3.7 7.3 6.2 5.9 6.6 4.3 1.5 1 1 0 1 1 1 0 Protein trafficking PGA2 HSP70 PF00012.15 EEQ71661.1 - 1.3e-271 901.8 5.5 1.5e-271 901.6 3.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEQ71661.1 - 3.8e-16 58.5 0.0 7e-15 54.4 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EEQ71661.1 - 0.0022 17.6 0.0 0.0063 16.1 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EEQ71661.1 - 0.0064 15.6 0.1 0.048 12.7 0.0 2.1 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase FtsA PF14450.1 EEQ71661.1 - 0.023 14.5 4.0 2.6 7.9 0.4 3.4 2 2 0 2 2 2 0 Cell division protein FtsA Transp_cyt_pur PF02133.10 EEQ71662.1 - 7.9e-64 215.8 23.5 1.2e-63 215.2 14.8 1.9 2 0 0 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin McyA_C PF12593.3 EEQ71662.1 - 0.028 14.1 0.1 0.061 13.0 0.1 1.5 1 0 0 1 1 1 0 Microcystin synthetase C terminal Glu_synthase PF01645.12 EEQ71663.1 - 2.6e-159 530.0 0.0 4e-159 529.4 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EEQ71663.1 - 4.8e-128 426.8 0.0 6.3e-128 426.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EEQ71663.1 - 6e-120 399.8 0.0 2.2e-119 398.0 0.0 1.8 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.14 EEQ71663.1 - 5.6e-65 218.1 1.7 1.1e-64 217.1 1.2 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EEQ71663.1 - 5.1e-22 77.5 0.3 1.4e-21 76.1 0.0 1.9 2 0 0 2 2 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EEQ71663.1 - 4.3e-18 65.9 0.0 1.1e-17 64.5 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEQ71663.1 - 2.3e-10 40.8 0.4 0.00029 20.9 0.1 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEQ71663.1 - 1.4e-09 38.1 0.1 2.5e-06 27.7 0.1 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEQ71663.1 - 2.6e-09 36.9 0.1 1e-08 35.0 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EEQ71663.1 - 5.6e-07 29.0 0.2 9.2e-07 28.2 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EEQ71663.1 - 4.3e-06 25.8 0.7 6.9e-05 21.9 0.3 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EEQ71663.1 - 4.1e-05 22.2 0.2 4.1e-05 22.2 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EEQ71663.1 - 5e-05 22.3 1.1 0.00028 19.8 0.3 2.4 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.2 EEQ71663.1 - 6.9e-05 22.0 0.0 0.00013 21.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EEQ71663.1 - 0.00046 19.3 0.0 0.00092 18.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 EEQ71663.1 - 0.00078 19.6 0.8 0.36 11.1 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EEQ71663.1 - 0.0011 18.5 0.1 0.013 15.1 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EEQ71663.1 - 0.0021 17.1 0.1 0.0084 15.2 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_Gly3P_dh_N PF01210.18 EEQ71663.1 - 0.0067 16.1 0.2 0.015 15.0 0.0 1.7 2 0 0 2 2 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 EEQ71663.1 - 0.011 14.6 2.6 0.027 13.3 1.3 2.0 1 1 1 2 2 2 0 Glucose inhibited division protein A FMO-like PF00743.14 EEQ71663.1 - 0.047 11.9 0.1 0.59 8.2 0.0 2.5 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 EEQ71663.1 - 0.075 12.8 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding DJ-1_PfpI PF01965.19 EEQ71663.1 - 0.13 11.6 0.0 0.31 10.4 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family FMN_dh PF01070.13 EEQ71663.1 - 0.15 10.8 1.1 0.51 9.1 0.6 1.8 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Shikimate_DH PF01488.15 EEQ71663.1 - 0.17 11.9 0.4 30 4.7 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EEQ71663.1 - 1.5 8.4 2.7 0.7 9.5 0.1 1.8 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3128 PF11326.3 EEQ71664.1 - 2.7e-31 107.5 4.6 4.7e-31 106.7 3.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Guanylin PF02058.10 EEQ71664.1 - 0.11 12.6 0.2 0.21 11.6 0.2 1.5 1 0 0 1 1 1 0 Guanylin precursor MGC-24 PF05283.6 EEQ71664.1 - 0.23 11.2 14.0 0.39 10.4 9.7 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) TraG-D_C PF12696.2 EEQ71664.1 - 1 9.2 4.5 26 4.7 0.0 2.2 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG Pex14_N PF04695.8 EEQ71664.1 - 7.6 6.5 18.6 0.092 12.7 5.6 2.2 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RNA12 PF10443.4 EEQ71665.1 - 2.2e-161 537.1 0.3 3.5e-161 536.5 0.2 1.3 1 0 0 1 1 1 1 RNA12 protein RRM_5 PF13893.1 EEQ71665.1 - 4.5e-05 23.1 0.0 0.00075 19.2 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 EEQ71665.1 - 0.00019 21.1 0.1 0.00095 18.9 0.0 2.0 1 1 0 1 1 1 1 Archaeal ATPase RRM_1 PF00076.17 EEQ71665.1 - 0.00073 19.1 0.0 0.0032 17.0 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TAFH PF07531.9 EEQ71665.1 - 0.018 14.6 0.0 0.56 9.8 0.0 2.5 2 0 0 2 2 2 0 NHR1 homology to TAF AAA_19 PF13245.1 EEQ71665.1 - 0.034 13.8 0.2 0.25 11.1 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain Amidase PF01425.16 EEQ71666.1 - 7e-63 213.0 0.1 2e-50 171.9 0.1 2.1 2 0 0 2 2 2 2 Amidase p450 PF00067.17 EEQ71667.1 - 1.5e-16 60.0 0.0 1.4e-15 56.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 EEQ71668.1 - 1.6e-19 68.9 2.3 7e-08 32.0 0.0 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat DUF3639 PF12341.3 EEQ71668.1 - 2.9e-11 43.1 3.2 2.9e-11 43.1 2.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 EEQ71668.1 - 1.3e-05 24.1 0.0 4.4e-05 22.4 0.0 1.8 2 1 0 2 2 2 1 Coatomer WD associated region eIF2A PF08662.6 EEQ71668.1 - 0.00029 20.6 0.0 0.098 12.3 0.0 3.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A MMS1_N PF10433.4 EEQ71668.1 - 0.043 11.9 0.0 0.28 9.2 0.0 2.3 3 0 0 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term DNA_pol_alpha_N PF12254.3 EEQ71668.1 - 0.085 12.6 3.0 0.27 11.0 2.1 1.8 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal PQQ_3 PF13570.1 EEQ71668.1 - 0.58 10.5 3.2 15 6.0 0.1 3.4 4 0 0 4 4 4 0 PQQ-like domain MFS_1 PF07690.11 EEQ71670.1 - 2.4e-35 121.8 20.6 2.4e-35 121.8 14.3 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ71670.1 - 3.1e-07 29.3 3.1 3.1e-07 29.3 2.2 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter DUF1129 PF06570.6 EEQ71670.1 - 1.2 8.4 5.5 3.7 6.8 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1129) VTC PF09359.5 EEQ71672.1 - 6.4e-89 297.7 0.1 1e-88 297.0 0.0 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EEQ71672.1 - 8.5e-22 78.2 9.7 5.4e-20 72.3 3.6 2.8 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 EEQ71672.1 - 1.5e-07 31.5 5.3 1.5e-07 31.5 3.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) NICE-3 PF07406.6 EEQ71672.1 - 0.087 12.3 2.8 0.13 11.7 0.1 2.6 3 1 0 3 3 3 0 NICE-3 protein 6PF2K PF01591.13 EEQ71673.1 - 6.1e-69 231.4 0.0 1.3e-47 161.7 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EEQ71673.1 - 5.2e-29 101.3 0.0 9.7e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EEQ71673.1 - 1.3e-06 28.3 0.0 0.065 13.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EEQ71673.1 - 0.0016 19.2 0.0 0.007 17.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EEQ71673.1 - 0.003 16.6 0.6 1.7 7.6 0.0 2.7 3 0 0 3 3 3 2 Zeta toxin KTI12 PF08433.5 EEQ71673.1 - 0.049 12.8 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF202 PF02656.10 EEQ71674.1 - 0.003 17.7 5.9 0.037 14.2 4.1 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF202) DUF998 PF06197.8 EEQ71674.1 - 0.073 12.3 2.9 0.3 10.3 2.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF998) FMN_dh PF01070.13 EEQ71675.1 - 1.7e-99 333.0 0.0 2.3e-99 332.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EEQ71675.1 - 4.1e-22 77.7 0.0 1.5e-21 75.9 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 EEQ71675.1 - 4.4e-07 29.1 0.4 0.00071 18.5 0.1 2.6 2 1 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EEQ71675.1 - 9.6e-07 28.0 0.0 1.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ATP11 PF06644.6 EEQ71675.1 - 0.00038 20.0 0.1 0.00063 19.3 0.1 1.3 1 0 0 1 1 1 1 ATP11 protein NMO PF03060.10 EEQ71675.1 - 0.07 12.2 2.7 1.2 8.2 0.1 2.7 1 1 1 2 2 2 0 Nitronate monooxygenase Pkinase PF00069.20 EEQ71677.1 - 2.9e-16 59.4 0.0 9.7e-09 34.7 0.0 2.6 1 1 2 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ71677.1 - 8.8e-09 34.8 0.0 0.00025 20.2 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Cauli_VI PF01693.11 EEQ71678.1 - 1.8e-33 114.2 5.3 4.5e-17 61.8 0.1 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 EEQ71678.1 - 2.9e-29 102.0 0.0 4.6e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 RNase H Na_H_Exchanger PF00999.16 EEQ71679.1 - 3.5e-36 124.5 22.8 4.5e-36 124.1 15.8 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pkinase PF00069.20 EEQ71680.1 - 2.9e-14 52.8 0.0 8.2e-11 41.5 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain FHA PF00498.21 EEQ71680.1 - 1.7e-08 34.4 0.2 6.3e-08 32.6 0.1 1.9 2 0 0 2 2 2 1 FHA domain Pkinase_Tyr PF07714.12 EEQ71680.1 - 2.5e-05 23.4 0.0 0.02 13.9 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEQ71680.1 - 0.0016 17.4 0.0 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Med20 PF08612.6 EEQ71682.1 - 4.3e-89 297.5 0.0 1.2e-88 295.9 0.0 1.6 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Pex14_N PF04695.8 EEQ71682.1 - 0.00086 19.3 4.4 0.0013 18.7 3.0 1.5 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.3 EEQ71682.1 - 0.018 14.4 4.5 0.029 13.7 3.2 1.3 1 0 0 1 1 1 0 Spt20 family Suf PF05843.9 EEQ71682.1 - 0.027 14.1 8.6 0.037 13.7 6.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Serinc PF03348.10 EEQ71682.1 - 0.029 13.1 0.7 0.04 12.6 0.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) PAT1 PF09770.4 EEQ71682.1 - 0.063 11.5 26.6 0.079 11.1 18.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF3_subunit PF08597.5 EEQ71682.1 - 0.25 10.8 6.2 0.38 10.2 4.3 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4557 PF15101.1 EEQ71682.1 - 0.36 10.6 12.6 0.52 10.1 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) CDK5_activator PF03261.10 EEQ71682.1 - 0.55 9.5 7.4 0.74 9.0 5.1 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Med15 PF09606.5 EEQ71682.1 - 4.3 5.3 33.4 7.1 4.6 23.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Hid1 PF12722.2 EEQ71682.1 - 6.3 4.3 6.6 7.9 4.0 4.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EF-hand_1 PF00036.27 EEQ71683.1 - 8.9e-41 134.1 12.8 1.5e-09 36.4 0.6 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EEQ71683.1 - 5.8e-36 122.4 6.4 1e-19 70.4 1.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EEQ71683.1 - 2.6e-34 116.6 12.3 1.1e-15 56.9 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EEQ71683.1 - 5.2e-30 100.6 8.4 1.7e-09 36.7 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EEQ71683.1 - 1.6e-25 87.2 9.7 1.9e-06 26.9 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EEQ71683.1 - 2.8e-15 55.9 0.3 3.4e-08 33.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EEQ71683.1 - 7.6e-09 35.2 2.4 0.00096 18.8 0.2 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EEQ71683.1 - 2.3e-08 34.0 0.1 0.0061 16.5 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EEQ71683.1 - 7.9e-08 31.8 0.1 0.031 13.8 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EEQ71683.1 - 9.3e-07 28.7 2.0 7.2e-06 25.8 0.2 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 EEQ71683.1 - 0.00019 21.2 0.5 0.48 10.1 0.0 2.7 1 1 2 3 3 3 2 Tellurite resistance protein TerB Caleosin PF05042.8 EEQ71683.1 - 0.00051 19.6 0.2 0.061 12.8 0.1 2.7 1 1 0 1 1 1 1 Caleosin related protein Tenui_NCP PF04876.7 EEQ71683.1 - 0.003 17.1 0.3 0.31 10.5 0.0 2.7 2 1 1 3 3 3 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 EEQ71683.1 - 0.0047 16.9 0.7 1.8 8.5 0.0 2.6 3 0 0 3 3 2 1 RNA polymerase Rpb4 Toprim_2 PF13155.1 EEQ71683.1 - 0.013 15.8 1.3 2.7 8.3 0.0 2.5 1 1 1 2 2 2 0 Toprim-like DUF3349 PF11829.3 EEQ71683.1 - 0.057 13.8 0.4 15 6.1 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) YqeY PF09424.5 EEQ71683.1 - 0.098 12.5 0.5 0.87 9.4 0.2 2.0 1 1 1 2 2 2 0 Yqey-like protein RloB PF13707.1 EEQ71683.1 - 0.11 12.1 2.6 1 8.9 0.4 2.2 1 1 1 2 2 2 0 RloB-like protein EF-hand_10 PF14788.1 EEQ71683.1 - 0.28 10.8 2.3 1.2 8.8 0.1 3.0 1 1 3 4 4 4 0 EF hand SNARE PF05739.14 EEQ71684.1 - 4.8e-18 64.5 6.8 3.4e-17 61.8 2.0 2.7 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EEQ71684.1 - 2.1e-12 47.0 1.3 2.1e-12 47.0 0.9 2.2 2 0 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 EEQ71684.1 - 0.0018 17.8 1.8 0.0018 17.8 1.2 2.2 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF349 PF03993.7 EEQ71684.1 - 0.033 14.3 1.3 0.23 11.6 0.2 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) DNA_repr_REX1B PF14966.1 EEQ71684.1 - 0.16 12.3 0.1 0.16 12.3 0.1 2.2 3 0 0 3 3 3 0 DNA repair REX1-B SAC3 PF12209.3 EEQ71684.1 - 0.18 11.9 1.4 0.53 10.4 0.0 2.5 3 0 0 3 3 3 0 Leucine permease transcriptional regulator helical domain Syntaxin_2 PF14523.1 EEQ71684.1 - 3.1 7.8 9.2 1.9 8.5 2.5 2.8 2 2 1 3 3 3 0 Syntaxin-like protein CTD_bind PF04818.8 EEQ71685.1 - 2e-20 72.7 0.6 3.9e-20 71.8 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Clathrin_lg_ch PF01086.12 EEQ71686.1 - 1.6e-68 231.0 1.8 2e-68 230.7 1.2 1.1 1 0 0 1 1 1 1 Clathrin light chain ATP-synt_B PF00430.13 EEQ71686.1 - 1.2 8.9 5.6 1.8 8.3 3.9 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Acyl_transf_3 PF01757.17 EEQ71687.1 - 4.8e-22 78.2 32.7 6.6e-22 77.7 22.7 1.2 1 0 0 1 1 1 1 Acyltransferase family Acyl_transf_3 PF01757.17 EEQ71688.1 - 8e-28 97.2 44.9 4.3e-27 94.8 31.1 1.9 1 1 0 1 1 1 1 Acyltransferase family DUF418 PF04235.7 EEQ71688.1 - 0.71 9.5 18.1 0.086 12.5 8.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF418) Mannosyl_trans3 PF11051.3 EEQ71689.1 - 1.9e-73 247.1 0.0 9.9e-73 244.8 0.0 1.9 1 1 0 1 1 1 1 Mannosyltransferase putative CDC37_N PF03234.9 EEQ71690.1 - 2.6e-59 200.5 7.7 2.6e-59 200.5 5.3 2.1 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EEQ71690.1 - 1.6e-44 151.4 0.0 4.5e-44 149.9 0.0 1.7 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EEQ71690.1 - 2.8e-23 81.6 6.1 2.8e-23 81.6 4.2 3.1 3 1 0 3 3 3 1 Cdc37 C terminal domain MecA_N PF05223.6 EEQ71690.1 - 0.042 13.9 0.5 0.042 13.9 0.4 2.1 2 0 0 2 2 2 0 NTF2-like N-terminal transpeptidase domain HTH_22 PF13309.1 EEQ71690.1 - 0.063 13.0 0.1 0.22 11.2 0.0 2.0 1 0 0 1 1 1 0 HTH domain DUF3287 PF11690.3 EEQ71690.1 - 0.073 13.1 4.3 0.97 9.5 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) DUF1268 PF06896.6 EEQ71690.1 - 0.15 12.4 4.5 0.053 13.8 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1268) DUF4407 PF14362.1 EEQ71690.1 - 5 5.9 6.5 1.7 7.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ABC_membrane PF00664.18 EEQ71691.1 - 1.2e-45 156.0 8.6 1.6e-45 155.6 5.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EEQ71691.1 - 2e-37 128.5 0.0 1e-36 126.2 0.0 2.2 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EEQ71691.1 - 1.3e-05 24.5 0.0 0.0011 18.2 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEQ71691.1 - 0.00013 22.0 0.1 0.63 9.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EEQ71691.1 - 0.0018 17.7 0.0 0.0042 16.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EEQ71691.1 - 0.002 18.2 0.1 0.011 15.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEQ71691.1 - 0.0033 17.4 0.4 0.018 15.0 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EEQ71691.1 - 0.0067 17.2 0.0 0.016 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EEQ71691.1 - 0.013 14.9 0.0 0.076 12.4 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein SbcCD_C PF13558.1 EEQ71691.1 - 0.015 15.1 6.0 0.16 11.8 0.3 3.7 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 EEQ71691.1 - 0.017 14.9 0.1 0.82 9.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_10 PF12846.2 EEQ71691.1 - 0.018 14.5 0.4 0.05 13.0 0.1 1.9 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.24 EEQ71691.1 - 0.021 14.9 0.0 0.11 12.6 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.4 EEQ71691.1 - 0.023 13.3 0.4 0.066 11.7 0.1 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_25 PF13481.1 EEQ71691.1 - 0.029 13.7 0.3 0.15 11.4 0.2 2.0 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EEQ71691.1 - 0.054 13.5 0.0 0.5 10.4 0.0 2.5 3 0 0 3 3 2 0 Sigma-54 interaction domain DUF258 PF03193.11 EEQ71691.1 - 0.059 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EEQ71691.1 - 0.062 13.6 0.5 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Nucleoside_tran PF01733.13 EEQ71692.1 - 8.7e-42 143.3 8.2 8.7e-42 143.3 5.7 2.2 2 1 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.11 EEQ71692.1 - 2e-08 33.3 28.8 9.2e-05 21.3 10.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2393 PF09624.5 EEQ71692.1 - 0.91 9.0 0.0 0.91 9.0 0.0 3.4 5 0 0 5 5 5 0 Protein of unknown function (DUF2393) zf-DHHC PF01529.15 EEQ71692.1 - 5.9 6.2 14.4 2.9 7.2 0.0 3.3 3 0 0 3 3 3 0 DHHC palmitoyltransferase Fungal_trans PF04082.13 EEQ71693.1 - 5.3e-13 48.4 0.3 2.2e-12 46.4 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3635 PF12330.3 EEQ71694.1 - 1.1e-05 25.4 1.1 4e-05 23.6 0.7 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3635) DUF2404 PF10296.4 EEQ71695.1 - 8.4e-05 22.6 0.0 0.00018 21.5 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DUF1682 PF07946.9 EEQ71696.1 - 4.5e-113 377.3 0.0 5.3e-113 377.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) COX7a PF02238.10 EEQ71697.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIa PPR_3 PF13812.1 EEQ71698.1 - 5.4e-05 23.1 0.0 0.0057 16.8 0.0 3.8 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.15 EEQ71698.1 - 0.0047 16.8 0.1 7.3 6.8 0.0 4.2 4 0 0 4 4 4 1 PPR repeat PPR_2 PF13041.1 EEQ71698.1 - 0.086 12.8 0.2 0.65 10.0 0.0 2.4 3 0 0 3 3 3 0 PPR repeat family DUF77 PF01910.12 EEQ71700.1 - 9.3e-33 111.7 0.4 1.1e-32 111.5 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF77 Ykof PF07615.6 EEQ71700.1 - 0.02 15.0 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 YKOF-related Family Ins_P5_2-kin PF06090.7 EEQ71703.1 - 2e-70 237.2 0.0 2.6e-70 236.9 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Nitroreductase PF00881.19 EEQ71704.1 - 8.8e-16 58.1 0.0 1.1e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family NAD_binding_10 PF13460.1 EEQ71705.1 - 6.7e-12 45.7 0.0 9.6e-11 42.0 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEQ71705.1 - 7e-08 32.1 0.0 1.7e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEQ71705.1 - 7.8e-06 24.7 0.0 2.6e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EEQ71705.1 - 1.6e-05 24.8 0.0 6.7e-05 22.8 0.0 1.9 1 1 1 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EEQ71705.1 - 0.021 13.7 0.0 3.9 6.3 0.0 2.4 2 1 0 2 2 2 0 Male sterility protein RmlD_sub_bind PF04321.12 EEQ71705.1 - 0.034 13.0 0.0 0.12 11.2 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EEQ71705.1 - 0.14 11.0 0.0 0.25 10.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein YEATS PF03366.11 EEQ71706.1 - 1.4e-35 120.8 1.0 2.1e-35 120.2 0.7 1.3 1 0 0 1 1 1 1 YEATS family PEP-utilisers_N PF05524.8 EEQ71706.1 - 0.022 14.5 0.7 0.13 12.0 0.6 1.9 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal SYF2 PF08231.7 EEQ71707.1 - 4e-53 179.6 14.8 4e-53 179.6 10.2 1.9 2 0 0 2 2 2 1 SYF2 splicing factor Velvet PF11754.3 EEQ71709.1 - 1.1e-48 165.4 0.0 1.8e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 Velvet factor TPR_12 PF13424.1 EEQ71710.1 - 0.19 11.6 3.0 1 9.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EEQ71710.1 - 0.64 10.0 3.1 0.83 9.6 0.0 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_L12 PF00542.14 EEQ71711.1 - 3.4e-19 68.5 5.9 4.9e-18 64.8 3.3 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain PP2C_C PF07830.8 EEQ71711.1 - 0.072 13.2 0.3 7.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain OEP PF02321.13 EEQ71712.1 - 0.015 14.9 0.4 0.017 14.7 0.3 1.0 1 0 0 1 1 1 0 Outer membrane efflux protein Cullin PF00888.17 EEQ71712.1 - 0.073 11.6 0.0 0.073 11.6 0.0 1.0 1 0 0 1 1 1 0 Cullin family Cpn60_TCP1 PF00118.19 EEQ71713.1 - 2.1e-128 428.9 5.6 1.8e-127 425.9 3.9 1.9 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family EAL PF00563.15 EEQ71713.1 - 0.098 12.1 0.1 0.32 10.4 0.0 1.8 2 0 0 2 2 2 0 EAL domain Nucleo_P87 PF07267.6 EEQ71713.1 - 0.17 10.5 0.3 0.3 9.7 0.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Cwf_Cwc_15 PF04889.7 EEQ71713.1 - 0.2 11.3 6.6 0.32 10.6 4.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 EEQ71713.1 - 4.4 5.2 7.1 7 4.5 4.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Peptidase_M48 PF01435.13 EEQ71714.1 - 7.6e-34 117.2 0.2 1e-33 116.7 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M48 ACT_6 PF13740.1 EEQ71714.1 - 0.088 12.5 0.4 0.18 11.5 0.2 1.5 1 0 0 1 1 1 0 ACT domain PH_10 PF15411.1 EEQ71715.1 - 1.1e-24 86.8 0.1 1.9e-24 86.0 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.1 EEQ71715.1 - 4.4e-09 36.0 7.1 7e-09 35.3 3.8 2.1 2 0 0 2 2 2 1 Ring finger domain VWA_3 PF13768.1 EEQ71715.1 - 5.4e-06 26.1 0.0 1.6e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_5 PF14634.1 EEQ71715.1 - 4.3e-05 23.1 4.8 8.9e-05 22.1 3.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EEQ71715.1 - 5.8e-05 22.6 1.6 0.00013 21.5 1.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ71715.1 - 0.00019 21.3 4.7 0.00044 20.2 3.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) VWA PF00092.23 EEQ71715.1 - 0.00075 19.2 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-rbx1 PF12678.2 EEQ71715.1 - 0.00084 19.4 1.1 0.0018 18.3 0.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EEQ71715.1 - 0.00091 18.8 5.1 0.002 17.7 3.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EEQ71715.1 - 0.24 11.4 4.5 0.57 10.2 3.1 1.7 1 0 0 1 1 1 0 RING-like domain FAD_binding_4 PF01565.18 EEQ71718.1 - 1.8e-14 53.3 0.3 7.7e-14 51.3 0.2 2.1 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEQ71718.1 - 3.9e-08 33.0 0.0 7.3e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF2838 PF10998.3 EEQ71719.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) E1_dh PF00676.15 EEQ71720.1 - 1.5e-114 381.7 0.1 1.9e-114 381.4 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EEQ71720.1 - 2.2e-05 23.5 0.0 3.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Spore_coat_CotO PF14153.1 EEQ71721.1 - 0.0015 18.0 14.7 0.0015 18.0 10.2 3.1 3 1 0 3 3 3 1 Spore coat protein CotO SPX PF03105.14 EEQ71721.1 - 0.0015 18.3 10.1 0.0015 18.3 7.0 3.2 2 1 0 2 2 2 1 SPX domain Med15 PF09606.5 EEQ71721.1 - 0.15 10.2 106.4 0.31 9.1 43.9 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal BRF1 PF07741.8 EEQ71721.1 - 7.9 6.7 0.0 7.9 6.7 0.0 5.0 3 2 1 4 4 4 0 Brf1-like TBP-binding domain S4 PF01479.20 EEQ71722.1 - 5.5e-14 51.3 0.0 1.1e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EEQ71722.1 - 0.03 13.9 0.0 0.076 12.6 0.0 1.6 1 0 0 1 1 1 0 S4 domain GDPD PF03009.12 EEQ71723.1 - 3.8e-20 72.4 0.0 8.1e-20 71.4 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF3636 PF12331.3 EEQ71725.1 - 9.2e-60 200.5 0.0 1.9e-59 199.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) Myosin_tail_1 PF01576.14 EEQ71725.1 - 0.0031 15.3 14.4 0.0047 14.7 10.0 1.2 1 0 0 1 1 1 1 Myosin tail DUF4358 PF14270.1 EEQ71725.1 - 0.0049 16.7 2.9 0.012 15.4 2.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4358) TMF_TATA_bd PF12325.3 EEQ71725.1 - 0.38 10.4 18.7 0.6 9.8 3.9 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Peptidase_S46 PF10459.4 EEQ71725.1 - 0.48 8.7 11.1 0.71 8.2 7.7 1.2 1 0 0 1 1 1 0 Peptidase S46 Spc7 PF08317.6 EEQ71725.1 - 0.68 8.5 13.9 1.2 7.7 9.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein FCH PF00611.18 EEQ71725.1 - 0.75 10.0 6.0 5.8 7.1 1.5 2.6 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain CDC37_N PF03234.9 EEQ71725.1 - 1.8 8.8 8.3 3.3 7.9 5.7 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF948 PF06103.6 EEQ71725.1 - 2.3 8.1 5.4 32 4.4 2.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FUSC PF04632.7 EEQ71725.1 - 3.3 6.0 11.1 3 6.1 4.1 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family IncA PF04156.9 EEQ71725.1 - 6.8 6.2 14.6 17 4.9 10.1 1.6 1 0 0 1 1 1 0 IncA protein DUF3450 PF11932.3 EEQ71725.1 - 6.9 5.8 16.7 0.93 8.7 4.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF812 PF05667.6 EEQ71725.1 - 8.2 4.7 18.2 4.5e+02 -1.0 13.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF812) CENP-F_leu_zip PF10473.4 EEQ71725.1 - 8.9 6.1 20.4 5.2 6.9 3.8 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CTP_transf_1 PF01148.15 EEQ71726.1 - 4.9e-83 278.7 26.2 5.9e-83 278.4 18.2 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Cyclin_N PF00134.18 EEQ71727.1 - 7.5e-12 44.9 0.0 2.8e-08 33.3 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain zf-C2H2 PF00096.21 EEQ71728.1 - 2.6e-12 46.3 68.3 0.018 15.3 0.1 12.3 11 1 1 12 12 12 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ71728.1 - 4e-12 45.5 55.4 0.015 15.6 0.2 11.4 9 2 2 11 11 11 6 C2H2-type zinc finger Rad50_zn_hook PF04423.9 EEQ71728.1 - 0.021 14.2 1.5 1.2 8.6 0.0 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-met PF12874.2 EEQ71728.1 - 0.05 13.8 0.3 0.05 13.8 0.2 9.7 11 0 0 11 11 11 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EEQ71728.1 - 0.083 13.0 0.4 0.083 13.0 0.2 10.4 10 1 1 11 11 11 0 Zinc-finger double-stranded RNA-binding zf-TFIIB PF13453.1 EEQ71728.1 - 0.13 11.4 0.2 0.13 11.4 0.1 5.0 4 0 0 4 4 4 0 Transcription factor zinc-finger WAC_Acf1_DNA_bd PF10537.4 EEQ71728.1 - 0.33 11.1 3.6 4.8 7.4 0.1 3.1 2 1 1 3 3 3 0 ATP-utilising chromatin assembly and remodelling N-terminal DUF164 PF02591.10 EEQ71728.1 - 5.8 6.8 16.1 10 6.0 0.5 4.5 4 0 0 4 4 4 0 Putative zinc ribbon domain GST_N_3 PF13417.1 EEQ71729.1 - 5.3e-21 74.6 0.5 1.4e-20 73.2 0.3 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEQ71729.1 - 1.6e-13 50.4 0.0 3.1e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EEQ71729.1 - 5.6e-06 26.4 0.0 1.1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEQ71729.1 - 7.3e-06 25.7 0.1 1.5e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EEQ71729.1 - 2e-05 24.4 0.0 4.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEQ71729.1 - 0.002 18.5 0.0 0.0039 17.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Arm PF00514.18 EEQ71730.1 - 5.8e-15 54.4 2.5 0.00015 21.4 0.0 8.5 8 1 0 8 8 8 4 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EEQ71730.1 - 5.5e-05 22.9 4.4 2.9 8.1 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EEQ71730.1 - 0.014 15.8 10.0 5.2 7.6 0.1 6.4 7 2 1 8 8 8 0 HEAT-like repeat Cyclin PF08613.6 EEQ71731.1 - 1.5e-28 100.0 1.3 2.4e-27 96.2 0.9 2.8 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EEQ71731.1 - 0.00014 21.4 0.0 0.00028 20.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain dCMP_cyt_deam_1 PF00383.17 EEQ71732.1 - 0.0044 16.6 0.4 0.018 14.6 0.2 1.9 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region BC10 PF06726.7 EEQ71733.1 - 2.9e-16 59.2 10.2 5.3e-16 58.3 7.1 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Glyoxalase_2 PF12681.2 EEQ71735.1 - 1.3e-07 32.1 0.1 1.7e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EEQ71735.1 - 0.0024 17.8 0.0 0.012 15.6 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Lac_bphage_repr PF06543.7 EEQ71737.1 - 0.058 12.9 2.4 0.12 11.9 1.7 1.4 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor Phenol_monoox PF04663.7 EEQ71737.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Phenol hydroxylase conserved region Tegument_dsDNA PF12818.2 EEQ71738.1 - 0.065 12.0 0.0 0.079 11.8 0.0 1.1 1 0 0 1 1 1 0 dsDNA viral tegument protein Acetyltransf_1 PF00583.19 EEQ71738.1 - 0.081 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family APH PF01636.18 EEQ71739.1 - 4.3e-15 56.1 0.1 6e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EEQ71739.1 - 0.12 11.3 0.0 2.5 6.9 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase EcKinase PF02958.15 EEQ71739.1 - 0.16 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Terminase_6 PF03237.10 EEQ71741.1 - 0.11 11.1 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Terminase-like family PGBA_C PF15437.1 EEQ71741.1 - 0.81 9.8 3.0 7.9 6.6 0.1 2.3 1 1 1 2 2 2 0 Plasminogen-binding protein pgbA C-terminal PNP_UDP_1 PF01048.15 EEQ71742.1 - 1.3e-14 53.7 0.7 4e-14 52.1 0.4 2.0 2 1 0 2 2 2 1 Phosphorylase superfamily NB-ARC PF00931.17 EEQ71742.1 - 1.8e-08 33.6 0.0 3.3e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.1 EEQ71742.1 - 7.7e-06 25.7 2.6 4.1e-05 23.4 0.3 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EEQ71742.1 - 0.00055 19.7 0.2 0.74 9.8 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat Arch_ATPase PF01637.13 EEQ71742.1 - 0.00087 19.0 0.0 0.0072 16.0 0.0 2.2 2 0 0 2 2 2 1 Archaeal ATPase TPR_1 PF00515.23 EEQ71742.1 - 0.0034 16.9 1.1 1.3 8.7 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_22 PF13401.1 EEQ71742.1 - 0.0053 16.8 0.0 0.028 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEQ71742.1 - 0.0063 16.5 5.2 0.06 13.3 2.0 3.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EEQ71742.1 - 0.031 14.1 0.1 0.14 12.0 0.0 2.2 3 0 0 3 3 3 0 AAA domain Occludin_ELL PF07303.8 EEQ71742.1 - 0.039 14.6 0.8 0.12 13.1 0.1 2.1 2 0 0 2 2 1 0 Occludin homology domain TPR_11 PF13414.1 EEQ71742.1 - 0.046 13.3 2.6 3.6 7.2 0.5 2.6 2 0 0 2 2 2 0 TPR repeat DUF2225 PF09986.4 EEQ71742.1 - 0.068 12.6 0.3 0.14 11.5 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_2 PF07719.12 EEQ71742.1 - 0.1 12.5 1.1 16 5.7 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat NACHT PF05729.7 EEQ71742.1 - 0.11 12.0 1.0 0.47 10.0 0.1 2.4 2 1 0 2 2 2 0 NACHT domain Chs3p PF12271.3 EEQ71744.1 - 5.3e-65 219.2 6.2 7.4e-65 218.8 4.3 1.1 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF423 PF04241.10 EEQ71744.1 - 0.43 10.5 6.1 0.26 11.2 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF423) IlvC PF01450.14 EEQ71746.1 - 0.11 12.4 1.5 0.13 12.1 1.0 1.1 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain TFIIA_gamma_N PF02268.11 EEQ71747.1 - 0.058 12.9 1.3 10 5.7 0.1 2.4 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain ASCH PF04266.9 EEQ71749.1 - 0.022 15.1 0.0 0.05 13.9 0.0 1.6 1 1 0 1 1 1 0 ASCH domain DUF2039 PF10217.4 EEQ71750.1 - 0.3 11.1 2.3 0.62 10.1 1.7 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) UCH PF00443.24 EEQ71751.1 - 9.4e-45 152.8 0.0 1.7e-44 151.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEQ71751.1 - 4.8e-19 68.8 0.0 1.1e-18 67.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF601 PF04642.7 EEQ71751.1 - 3.8 6.7 4.9 8 5.7 3.4 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF601 ERG4_ERG24 PF01222.12 EEQ71753.1 - 3.2e-141 470.7 18.9 3.7e-141 470.5 13.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Methyltransf_23 PF13489.1 EEQ71754.1 - 4.4e-24 85.0 0.0 1.7e-23 83.1 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ71754.1 - 2.3e-10 41.0 0.0 9.3e-10 39.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ71754.1 - 2.8e-08 34.1 0.0 4.9e-06 26.9 0.0 2.7 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ71754.1 - 9.8e-08 32.3 0.0 0.015 15.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ71754.1 - 7.4e-07 28.8 0.0 5.3e-05 22.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ71754.1 - 7.4e-06 25.9 0.0 3.2e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ71754.1 - 3.4e-05 24.1 0.0 0.00012 22.4 0.0 2.0 2 1 0 2 2 1 1 Methyltransferase domain FtsJ PF01728.14 EEQ71754.1 - 0.00015 21.8 0.0 0.00046 20.2 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EEQ71754.1 - 0.00081 18.5 0.0 0.028 13.5 0.0 2.4 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EEQ71754.1 - 0.0015 17.5 0.0 0.0072 15.3 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 EEQ71754.1 - 0.0092 15.3 0.0 0.079 12.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain DUF3606 PF12244.3 EEQ71754.1 - 0.11 12.1 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) Peptidase_M15_2 PF05951.8 EEQ71755.1 - 0.15 11.5 0.6 0.21 11.0 0.3 1.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF882) PspB PF06667.7 EEQ71755.1 - 1.1 9.2 3.5 5.2 7.0 0.1 2.1 2 0 0 2 2 2 0 Phage shock protein B Gp_dh_N PF00044.19 EEQ71757.1 - 0.013 15.4 1.5 0.015 15.2 1.1 1.1 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Peptidase_C97 PF05903.9 EEQ71757.1 - 0.016 15.0 0.2 0.023 14.4 0.2 1.2 1 0 0 1 1 1 0 PPPDE putative peptidase domain DUF458 PF04308.7 EEQ71757.1 - 0.041 13.5 1.9 0.059 13.0 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF458) DUF955 PF06114.8 EEQ71757.1 - 0.097 12.3 0.7 0.16 11.7 0.3 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF955) GIDA_assoc_3 PF13932.1 EEQ71757.1 - 0.1 12.6 1.0 0.22 11.6 0.7 1.5 1 0 0 1 1 1 0 GidA associated domain 3 DUF4181 PF13789.1 EEQ71757.1 - 3.7 7.5 6.7 1.1 9.2 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4181) FAD_binding_1 PF00667.15 EEQ71758.1 - 5.5e-41 140.4 0.0 7.9e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EEQ71758.1 - 1.4e-09 38.4 0.0 3e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Homeobox_KN PF05920.6 EEQ71761.1 - 5e-20 70.9 0.5 1.1e-19 69.8 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EEQ71761.1 - 4.5e-07 29.4 0.1 7.8e-07 28.6 0.1 1.4 1 0 0 1 1 1 1 Homeobox domain adh_short PF00106.20 EEQ71763.1 - 0.0039 17.1 0.0 0.0081 16.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase SRP72 PF08492.7 EEQ71764.1 - 1.9e-18 66.5 5.6 1.9e-18 66.5 3.9 2.4 2 0 0 2 2 2 1 SRP72 RNA-binding domain Apc3 PF12895.2 EEQ71764.1 - 0.002 18.2 0.1 7.1 6.8 0.0 3.8 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 vWA-TerF-like PF10138.4 EEQ71765.1 - 1e-07 31.9 0.0 1.7e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 EEQ71765.1 - 0.0016 18.5 0.0 0.0034 17.5 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain Hydrolase PF00702.21 EEQ71766.1 - 2.8e-18 67.1 0.0 9.1e-17 62.1 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EEQ71766.1 - 2e-16 59.7 0.5 2e-16 59.7 0.4 2.1 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 EEQ71766.1 - 8e-15 55.4 0.1 6.5e-14 52.5 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ71766.1 - 1.1e-10 41.3 0.0 3.2e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEQ71766.1 - 0.0015 18.1 0.0 0.0047 16.5 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CHASE PF03924.8 EEQ71770.1 - 0.075 12.2 0.1 0.093 11.9 0.0 1.1 1 0 0 1 1 1 0 CHASE domain MFS_1 PF07690.11 EEQ71772.1 - 4.3e-38 130.9 23.6 6.7e-38 130.2 16.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EEQ71772.1 - 0.0079 15.9 0.6 0.0079 15.9 0.4 2.9 3 0 0 3 3 3 1 MFS_1 like family DUF1230 PF06799.6 EEQ71772.1 - 0.13 12.1 0.2 0.35 10.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1230) NfeD PF01957.13 EEQ71772.1 - 0.19 11.8 9.9 7.3 6.7 0.0 3.6 2 1 2 4 4 4 0 NfeD-like C-terminal, partner-binding PGP_phosphatase PF09419.5 EEQ71774.1 - 1e-41 142.1 0.0 4.1e-41 140.1 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EEQ71774.1 - 0.00013 21.5 0.0 0.00027 20.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EEQ71774.1 - 0.0029 18.0 0.0 1.4 9.2 0.0 2.2 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase LSM PF01423.17 EEQ71775.1 - 4.9e-14 51.6 0.4 6.7e-14 51.2 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEQ71775.1 - 0.038 13.9 0.1 0.068 13.1 0.1 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain Tail_tube PF10618.4 EEQ71775.1 - 0.071 12.8 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Phage tail tube protein Adaptin_binding PF10199.4 EEQ71776.1 - 7.5e-10 39.2 0.7 2.4e-09 37.5 0.5 1.9 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 PTPLA PF04387.9 EEQ71777.1 - 1e-47 161.6 8.7 1.9e-47 160.7 6.0 1.5 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DUF4449 PF14613.1 EEQ71778.1 - 2.2e-55 187.0 6.5 2.2e-55 187.0 4.5 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF4449) DUF4211 PF13926.1 EEQ71779.1 - 1.6e-45 154.2 0.0 4.6e-45 152.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) BTB PF00651.26 EEQ71780.1 - 0.00085 19.2 0.0 0.0034 17.3 0.0 2.0 1 1 0 1 1 1 1 BTB/POZ domain MgtE PF01769.11 EEQ71781.1 - 0.019 15.2 0.0 0.022 15.0 0.0 1.1 1 0 0 1 1 1 0 Divalent cation transporter DUF4244 PF14029.1 EEQ71784.1 - 0.084 11.9 0.5 0.15 11.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) F-box-like PF12937.2 EEQ71786.1 - 1.5e-05 24.6 1.2 6.5e-05 22.5 0.1 2.6 2 0 0 2 2 2 1 F-box-like bZIP_1 PF00170.16 EEQ71787.1 - 0.00068 19.5 4.0 0.0017 18.2 2.8 1.7 1 0 0 1 1 1 1 bZIP transcription factor LolA PF03548.10 EEQ71787.1 - 0.0071 15.9 4.9 1.6 8.2 1.8 2.3 2 0 0 2 2 2 2 Outer membrane lipoprotein carrier protein LolA bZIP_2 PF07716.10 EEQ71787.1 - 0.0088 15.8 1.2 0.019 14.7 0.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper DUF3066 PF11266.3 EEQ71787.1 - 0.014 15.0 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3066) Cytomega_TRL10 PF06084.6 EEQ71788.1 - 0.0024 17.6 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 Cytomegalovirus TRL10 protein Mito_carr PF00153.22 EEQ71790.1 - 6.1e-38 128.4 18.8 7.1e-15 54.4 0.2 4.2 4 1 0 4 4 4 3 Mitochondrial carrier protein DUF2681 PF10883.3 EEQ71790.1 - 1.1 9.4 7.5 0.69 10.1 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) CDK2AP PF09806.4 EEQ71790.1 - 1.3 9.2 12.6 1.4 9.1 7.5 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Presenilin PF01080.12 EEQ71790.1 - 1.9 7.2 5.7 2.5 6.8 4.0 1.2 1 0 0 1 1 1 0 Presenilin Cu_bind_like PF02298.12 EEQ71791.1 - 0.047 13.4 0.1 0.19 11.5 0.1 1.9 1 1 0 1 1 1 0 Plastocyanin-like domain SMN PF06003.7 EEQ71792.1 - 0.081 12.0 1.8 0.085 11.9 0.4 1.6 1 1 0 1 1 1 0 Survival motor neuron protein (SMN) RRM_1 PF00076.17 EEQ71793.1 - 6.4e-15 54.5 0.0 1.4e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ71793.1 - 2.9e-10 39.9 0.0 5.4e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ71793.1 - 1.1e-08 34.8 0.0 3e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEQ71793.1 - 0.017 14.9 0.0 0.072 12.8 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif CHD5 PF04420.9 EEQ71794.1 - 3e-58 196.0 0.9 3.5e-58 195.8 0.6 1.0 1 0 0 1 1 1 1 CHD5-like protein Lebercilin PF15619.1 EEQ71794.1 - 0.00037 19.9 1.3 0.00048 19.5 0.9 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Gly-zipper_OmpA PF13436.1 EEQ71794.1 - 0.063 12.9 5.4 0.13 11.9 3.7 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain PPTA PF01239.17 EEQ71795.1 - 0.019 14.3 5.2 3.5 7.1 0.0 3.8 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat 4F5 PF04419.9 EEQ71796.1 - 1.4e-08 35.3 10.0 1.4e-08 35.3 6.9 2.5 2 1 0 2 2 2 1 4F5 protein family Phage_Gp23 PF10669.4 EEQ71796.1 - 0.19 11.8 2.9 0.2 11.7 2.0 1.0 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) ABC2_membrane_5 PF13346.1 EEQ71797.1 - 0.66 9.2 14.0 0.095 11.9 0.7 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein TRAM_LAG1_CLN8 PF03798.11 EEQ71800.1 - 1.7e-40 138.6 22.4 3e-40 137.8 15.5 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 EEQ71800.1 - 1.2e-17 63.1 1.0 3e-17 61.8 0.0 2.1 2 0 0 2 2 2 1 TRAM1-like protein DUF788 PF05620.6 EEQ71800.1 - 0.39 10.5 3.2 1.4 8.7 0.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF788) Fungal_trans PF04082.13 EEQ71801.1 - 1e-17 63.8 0.4 1e-17 63.8 0.3 2.0 3 0 0 3 3 3 1 Fungal specific transcription factor domain Neur_chan_memb PF02932.11 EEQ71801.1 - 0.58 9.9 4.5 1.1 9.1 0.0 2.4 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region ABC_membrane PF00664.18 EEQ71802.1 - 1.1e-78 264.3 38.8 1.6e-41 142.5 10.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEQ71802.1 - 1.1e-68 229.7 0.0 3.5e-34 118.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EEQ71802.1 - 4.5e-15 56.3 0.0 0.0023 17.9 0.0 4.5 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 EEQ71802.1 - 2.8e-12 46.3 7.4 5.3e-05 22.5 0.0 4.2 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EEQ71802.1 - 3.7e-09 35.6 2.6 0.00023 19.8 0.1 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 EEQ71802.1 - 4e-09 36.7 0.9 0.00053 20.0 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EEQ71802.1 - 8.7e-08 31.5 0.7 0.0018 17.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EEQ71802.1 - 1.2e-07 31.0 0.0 0.0076 15.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EEQ71802.1 - 6.9e-07 30.1 0.0 0.069 13.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EEQ71802.1 - 1.1e-06 28.7 1.9 0.026 14.6 0.1 3.9 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEQ71802.1 - 4e-06 26.3 1.8 0.11 11.9 0.1 3.2 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EEQ71802.1 - 4.5e-05 23.4 0.0 0.065 13.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EEQ71802.1 - 6.8e-05 22.7 0.0 1.3 8.9 0.0 3.9 3 1 1 4 4 4 1 AAA domain SbcCD_C PF13558.1 EEQ71802.1 - 0.00033 20.5 2.3 0.53 10.2 0.2 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 EEQ71802.1 - 0.00069 19.3 0.1 0.75 9.5 0.0 3.5 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EEQ71802.1 - 0.00094 19.4 0.0 2.8 8.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain G-alpha PF00503.15 EEQ71802.1 - 0.0017 17.1 0.1 0.34 9.5 0.0 2.1 2 0 0 2 2 2 1 G-protein alpha subunit AAA_15 PF13175.1 EEQ71802.1 - 0.0019 17.3 0.0 0.67 8.9 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 EEQ71802.1 - 0.0019 18.5 0.5 0.85 9.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EEQ71802.1 - 0.0024 18.0 2.9 6.1 7.0 0.5 4.2 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EEQ71802.1 - 0.0025 16.9 0.1 1.5 7.8 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin AAA_33 PF13671.1 EEQ71802.1 - 0.0029 17.5 0.0 2.4 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 EEQ71802.1 - 0.01 14.5 0.3 0.62 8.6 0.1 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein MMR_HSR1 PF01926.18 EEQ71802.1 - 0.012 15.5 0.0 7.8 6.4 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 EEQ71802.1 - 0.014 15.5 0.0 6.1 7.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.15 EEQ71802.1 - 0.016 14.9 0.1 0.66 9.6 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase MobB PF03205.9 EEQ71802.1 - 0.042 13.5 0.0 12 5.5 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 EEQ71802.1 - 0.068 12.6 0.3 1.2 8.6 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PRK PF00485.13 EEQ71802.1 - 0.13 11.7 0.0 16 5.0 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_10 PF12846.2 EEQ71802.1 - 0.21 10.9 1.6 8.6 5.7 0.0 3.1 4 0 0 4 4 3 0 AAA-like domain Fungal_trans_2 PF11951.3 EEQ71803.1 - 2.8e-16 59.1 0.1 2.1e-15 56.2 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Nitr_red_bet_C PF14711.1 EEQ71803.1 - 1.1 8.8 4.7 21 4.6 0.0 2.5 2 0 0 2 2 2 0 Respiratory nitrate reductase beta C-terminal Rad10 PF03834.9 EEQ71804.1 - 3.2e-30 103.6 0.0 6.6e-30 102.6 0.0 1.5 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EEQ71804.1 - 8.3e-05 22.6 0.0 0.00018 21.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.18 EEQ71804.1 - 0.016 14.8 0.0 0.037 13.7 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_2 PF12826.2 EEQ71804.1 - 0.021 14.7 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif RRM_1 PF00076.17 EEQ71805.1 - 5.2e-61 202.2 0.0 1.5e-19 69.4 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ71805.1 - 2.3e-43 145.9 0.0 1.2e-13 50.7 0.0 5.1 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ71805.1 - 8e-23 80.0 0.0 1.1e-08 34.8 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyt-b5 PF00173.23 EEQ71806.1 - 6.6e-10 38.6 0.0 7.9e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AA_permease PF00324.16 EEQ71807.1 - 3.3e-84 282.9 21.9 3.9e-84 282.7 15.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ71807.1 - 2.4e-17 62.6 21.0 3.1e-17 62.2 14.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 EEQ71807.1 - 0.01 15.5 3.2 0.01 15.5 2.2 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) Cupin_8 PF13621.1 EEQ71808.1 - 1.4e-23 83.6 0.0 3.4e-23 82.4 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EEQ71808.1 - 0.0067 16.6 0.0 0.13 12.5 0.0 2.5 1 1 1 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 EEQ71808.1 - 0.057 12.6 0.0 0.2 10.8 0.0 1.7 2 0 0 2 2 2 0 Cupin superfamily protein Cupin_2 PF07883.6 EEQ71808.1 - 0.15 11.5 0.0 0.34 10.4 0.0 1.6 2 0 0 2 2 2 0 Cupin domain Fungal_trans PF04082.13 EEQ71809.1 - 5.1e-21 74.7 0.1 9.6e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ71809.1 - 5.8e-06 26.1 14.9 9.7e-06 25.4 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prefoldin PF02996.12 EEQ71809.1 - 0.096 12.3 0.1 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Prefoldin subunit DUF948 PF06103.6 EEQ71809.1 - 1.4 8.8 2.7 2.9 7.7 0.0 2.7 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) GST_N_2 PF13409.1 EEQ71811.1 - 2e-10 40.4 0.0 5.2e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EEQ71811.1 - 1.4e-09 38.0 0.0 2.6e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEQ71811.1 - 6.7e-08 32.4 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEQ71811.1 - 9e-06 25.4 0.1 2.3e-05 24.2 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EEQ71811.1 - 9.3e-05 22.5 0.0 0.00042 20.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EEQ71811.1 - 0.025 15.0 0.0 0.044 14.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Sterol_MT_C PF08498.5 EEQ71811.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Sterol methyltransferase C-terminal MMR_HSR1 PF01926.18 EEQ71812.1 - 0.00039 20.3 0.0 0.00071 19.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EEQ71812.1 - 0.018 14.8 0.8 0.1 12.3 0.0 2.1 2 1 1 3 3 3 0 Dynamin family DUF883 PF05957.8 EEQ71812.1 - 0.031 14.6 0.4 0.061 13.7 0.3 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF258 PF03193.11 EEQ71812.1 - 0.058 12.5 0.1 0.17 11.0 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 TMEM171 PF15471.1 EEQ71812.1 - 2.2 6.9 6.6 3.9 6.1 4.6 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 F-box-like PF12937.2 EEQ71813.1 - 0.05 13.3 0.4 0.14 11.8 0.3 1.9 1 0 0 1 1 1 0 F-box-like MoaE PF02391.12 EEQ71814.1 - 1.3e-24 86.2 0.0 1.7e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 MoaE protein FAA_hydrolase PF01557.13 EEQ71816.1 - 4.8e-46 156.9 0.0 6.4e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EEQ71816.1 - 6.8e-26 90.3 0.0 1.2e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal ADSL_C PF10397.4 EEQ71816.1 - 0.16 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus GCV_T PF01571.16 EEQ71817.1 - 6.3e-56 189.0 0.0 8.6e-56 188.6 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EEQ71817.1 - 4.5e-18 65.0 0.4 8.1e-18 64.2 0.2 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DUF775 PF05603.7 EEQ71818.1 - 1.8e-64 216.9 0.0 2.1e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) GATase PF00117.23 EEQ71819.1 - 1.5e-12 47.4 0.0 2e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EEQ71819.1 - 0.0018 17.9 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 EEQ71819.1 - 0.023 14.1 0.1 0.13 11.6 0.1 2.1 1 1 0 1 1 1 0 Peptidase C26 Pribosyltran PF00156.22 EEQ71820.1 - 3.3e-16 59.1 0.0 4.4e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EEQ71820.1 - 0.016 14.4 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DUF4131 PF13567.1 EEQ71822.1 - 1.2 8.5 4.0 1.5 8.1 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2207 PF09972.4 EEQ71822.1 - 1.4 7.3 17.3 1.5 7.3 12.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Wzy_C PF04932.10 EEQ71822.1 - 2.5 7.8 17.0 3.2 7.5 11.8 1.2 1 0 0 1 1 1 0 O-Antigen ligase FA_hydroxylase PF04116.8 EEQ71822.1 - 2.8 8.3 7.3 3.7 7.9 5.1 1.3 1 0 0 1 1 1 0 Fatty acid hydroxylase superfamily DUF1700 PF08006.6 EEQ71822.1 - 3.8 6.7 25.6 5.4 6.2 17.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) F-box-like PF12937.2 EEQ71823.1 - 0.024 14.3 1.8 0.08 12.6 0.4 2.5 2 1 0 2 2 2 0 F-box-like PYST-C1 PF09690.5 EEQ71824.1 - 0.0019 17.8 0.7 0.0034 17.0 0.5 1.3 1 0 0 1 1 1 1 Plasmodium yoelii subtelomeric region (PYST-C1) PepSY_TM_1 PF13172.1 EEQ71825.1 - 0.33 10.7 7.4 0.38 10.5 0.4 3.0 2 0 0 2 2 2 0 PepSY-associated TM helix zf-C2H2_4 PF13894.1 EEQ71827.1 - 1.1e-05 25.3 23.4 0.002 18.3 1.8 5.0 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEQ71827.1 - 0.00034 20.6 4.3 0.00034 20.6 3.0 3.5 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EEQ71827.1 - 0.0024 18.1 23.2 0.0032 17.7 1.6 4.6 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEQ71827.1 - 0.0032 17.6 0.4 0.0032 17.6 0.3 3.6 3 1 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 EEQ71827.1 - 0.023 14.9 1.3 0.023 14.9 0.9 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-CHCC PF10276.4 EEQ71827.1 - 0.33 10.8 4.4 1.1 9.1 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger domain zf-FCS PF06467.9 EEQ71827.1 - 1.8 8.2 10.5 1.3 8.7 0.3 2.9 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif Adeno_PIX PF03955.9 EEQ71829.1 - 0.15 12.6 0.4 0.29 11.6 0.0 1.7 2 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Aa_trans PF01490.13 EEQ71830.1 - 1.9e-69 234.1 24.7 2.3e-69 233.8 17.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Rad52_Rad22 PF04098.10 EEQ71832.1 - 6.2e-61 204.6 0.0 9.5e-61 204.0 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein UBX PF00789.15 EEQ71833.1 - 1.7e-06 27.9 0.0 5.2e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 UBX domain UBA PF00627.26 EEQ71833.1 - 0.00012 21.8 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain zf-C2H2 PF00096.21 EEQ71833.1 - 0.024 14.9 0.3 0.044 14.1 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type GATA PF00320.22 EEQ71833.1 - 0.073 12.4 0.1 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 GATA zinc finger zf-C2H2_2 PF12756.2 EEQ71833.1 - 0.11 12.6 0.4 0.11 12.6 0.3 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EEQ71833.1 - 0.11 12.6 0.2 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Rtf2 PF04641.7 EEQ71833.1 - 0.12 11.5 16.7 0.19 10.9 11.6 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger DUF572 PF04502.8 EEQ71833.1 - 0.13 11.4 19.3 0.2 10.8 13.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF342 PF03961.8 EEQ71833.1 - 0.19 10.1 12.9 0.24 9.7 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SOBP PF15279.1 EEQ71833.1 - 0.58 10.4 8.3 0.74 10.1 5.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Ycf1 PF05758.7 EEQ71833.1 - 0.69 7.5 9.5 0.86 7.2 6.6 1.3 1 0 0 1 1 1 0 Ycf1 CpXC PF14353.1 EEQ71833.1 - 0.74 9.7 11.7 0.36 10.7 6.3 1.8 1 1 1 2 2 2 0 CpXC protein APG6 PF04111.7 EEQ71833.1 - 1.6 7.6 25.2 2.6 6.9 17.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Borrelia_P83 PF05262.6 EEQ71833.1 - 3.9 5.6 19.0 4.5 5.4 13.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein CAF-1_p150 PF11600.3 EEQ71833.1 - 4.3 6.6 40.8 6.2 6.1 28.3 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PLRV_ORF5 PF01690.12 EEQ71833.1 - 4.8 6.2 14.8 5.7 5.9 10.3 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DIT1_PvcA PF05141.7 EEQ71833.1 - 5.5 6.2 9.2 7.7 5.7 6.4 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein PsbW PF07123.7 EEQ71833.1 - 8.8 6.3 9.2 1.5 8.8 2.2 2.4 1 1 2 3 3 3 0 Photosystem II reaction centre W protein (PsbW) HSP70 PF00012.15 EEQ71834.1 - 1.5e-07 29.7 0.0 2.5e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Hsp70 protein Herpes_gE PF02480.11 EEQ71834.1 - 0.08 11.1 0.0 0.12 10.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E UPF0081 PF03652.10 EEQ71834.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0081) Motile_Sperm PF00635.21 EEQ71836.1 - 9.6e-22 76.6 1.5 3.3e-18 65.3 0.1 2.3 1 1 1 2 2 2 2 MSP (Major sperm protein) domain Lipid_DES PF08557.5 EEQ71837.1 - 1.3e-19 69.0 0.1 1.9e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) FA_desaturase PF00487.19 EEQ71837.1 - 2.3e-15 56.7 0.5 3.2e-15 56.2 0.3 1.2 1 0 0 1 1 1 1 Fatty acid desaturase CAP_N PF01213.14 EEQ71837.1 - 0.32 10.2 2.6 0.48 9.6 1.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Alpha-amyl_C PF09071.5 EEQ71839.1 - 0.051 13.3 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 Alpha-amylase, C terminal Porin_3 PF01459.17 EEQ71840.1 - 1.7e-71 240.7 2.8 1.9e-71 240.5 2.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin KdpC PF02669.10 EEQ71840.1 - 0.042 13.5 0.4 0.08 12.6 0.3 1.4 1 0 0 1 1 1 0 K+-transporting ATPase, c chain DUF3651 PF12371.3 EEQ71840.1 - 0.08 12.9 0.0 13 5.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3651) Asn_synthase PF00733.16 EEQ71841.1 - 1.5e-68 231.0 0.0 2e-68 230.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EEQ71841.1 - 7.2e-36 122.6 0.0 1.2e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EEQ71841.1 - 4.4e-27 94.6 0.0 8.2e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EEQ71841.1 - 7.2e-07 28.6 0.0 1.3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 EEQ71841.1 - 0.00098 18.0 0.0 0.0027 16.6 0.0 1.7 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 EEQ71841.1 - 0.003 16.3 0.0 0.013 14.2 0.0 1.6 1 1 1 2 2 2 1 Glutamine amidotransferases class-II UQ_con PF00179.21 EEQ71842.1 - 1.4e-48 163.9 0.0 1.5e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEQ71842.1 - 0.0034 17.1 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEQ71842.1 - 0.01 15.6 1.9 0.019 14.8 1.3 1.7 1 1 0 1 1 1 0 RWD domain KH_3 PF13014.1 EEQ71843.1 - 0.059 13.0 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 KH domain Peptidase_M24 PF00557.19 EEQ71844.1 - 5.9e-47 159.9 0.1 7.5e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DnaJ PF00226.26 EEQ71845.1 - 1.6e-22 79.0 0.8 2.4e-22 78.4 0.6 1.3 1 0 0 1 1 1 1 DnaJ domain DUF4510 PF14971.1 EEQ71845.1 - 0.12 12.5 0.5 0.29 11.2 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) Cytokin-bind PF09265.5 EEQ71846.1 - 0.042 12.9 0.1 0.077 12.1 0.1 1.5 1 1 1 2 2 2 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding HpcH_HpaI PF03328.9 EEQ71847.1 - 4e-43 146.8 0.0 1.6e-41 141.6 0.0 2.0 2 0 0 2 2 2 2 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EEQ71847.1 - 2.5e-11 43.0 0.0 5.9e-07 28.6 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold WD40 PF00400.27 EEQ71848.1 - 1.5e-22 78.5 21.4 7.7e-10 38.2 0.2 10.6 10 1 0 10 10 10 7 WD domain, G-beta repeat GHMP_kinases_N PF00288.21 EEQ71848.1 - 0.00071 19.6 0.0 0.24 11.4 0.0 2.8 2 0 0 2 2 2 2 GHMP kinases N terminal domain GFA PF04828.9 EEQ71849.1 - 6.4e-18 64.4 10.9 9.4e-09 35.1 0.0 3.5 4 0 0 4 4 4 2 Glutathione-dependent formaldehyde-activating enzyme Anp1 PF03452.9 EEQ71850.1 - 6.7e-107 356.6 0.0 8.4e-107 356.3 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 EEQ71850.1 - 0.0019 17.8 0.0 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Zip PF02535.17 EEQ71851.1 - 3.3e-59 200.4 7.9 1.8e-57 194.7 5.5 2.2 1 1 0 1 1 1 1 ZIP Zinc transporter DUF456 PF04306.8 EEQ71851.1 - 5 7.1 14.7 3.1 7.8 2.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF456) IGPD PF00475.13 EEQ71852.1 - 2.6e-54 183.0 0.1 3.7e-54 182.5 0.1 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DUF4507 PF14964.1 EEQ71852.1 - 0.12 11.0 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4507) DUF3550 PF12070.3 EEQ71853.1 - 0.071 11.8 0.0 0.078 11.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3550/UPF0682) GDPD PF03009.12 EEQ71854.1 - 8.4e-34 117.2 0.0 7.7e-33 114.0 0.0 2.2 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EEQ71854.1 - 0.0012 18.9 0.1 0.0045 17.1 0.1 2.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family FAD_binding_2 PF00890.19 EEQ71855.1 - 1.1e-85 288.0 0.4 1.4e-85 287.6 0.3 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EEQ71855.1 - 2.9e-21 75.0 0.3 1.5e-19 69.5 0.1 2.9 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EEQ71855.1 - 8.3e-13 47.9 1.9 1.5e-11 43.8 1.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EEQ71855.1 - 3.3e-11 42.9 0.3 9.2e-11 41.4 0.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEQ71855.1 - 1.4e-08 34.5 2.0 4.5e-08 33.0 0.2 2.6 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEQ71855.1 - 2.9e-08 33.8 0.0 3.5e-06 27.0 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEQ71855.1 - 1.2e-06 27.2 5.6 1e-05 24.2 0.8 3.0 2 1 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.19 EEQ71855.1 - 5e-05 22.5 0.1 0.4 9.6 0.0 3.1 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Thi4 PF01946.12 EEQ71855.1 - 7.1e-05 22.0 0.3 0.01 14.9 0.0 2.5 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 EEQ71855.1 - 0.00023 20.1 1.8 0.13 11.0 0.3 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EEQ71855.1 - 0.00097 19.2 0.9 0.007 16.4 0.6 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EEQ71855.1 - 0.0016 17.5 0.3 0.0016 17.5 0.2 1.6 2 1 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EEQ71855.1 - 0.0035 17.1 0.6 0.034 13.9 0.4 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EEQ71855.1 - 0.064 13.6 1.7 2 8.8 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 EEQ71855.1 - 0.13 10.5 0.1 0.24 9.6 0.1 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor FBPase PF00316.15 EEQ71856.1 - 2.1e-120 401.4 0.0 2.4e-120 401.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Glycoprotein_B PF00606.13 EEQ71860.1 - 0.35 8.8 3.0 0.4 8.6 2.1 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B Aldedh PF00171.17 EEQ71861.1 - 1.9e-119 399.0 0.0 2.5e-119 398.6 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family YCII PF03795.9 EEQ71862.1 - 1.5e-09 37.9 0.0 2.1e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain Aerolysin PF01117.15 EEQ71862.1 - 0.033 13.1 0.0 0.054 12.4 0.0 1.4 1 1 0 1 1 1 0 Aerolysin toxin Ureidogly_hydro PF04115.7 EEQ71862.1 - 0.062 12.6 0.1 0.11 11.7 0.0 1.5 1 1 0 1 1 1 0 Ureidoglycolate hydrolase AMP-binding PF00501.23 EEQ71863.1 - 1.1e-86 290.8 0.0 1.4e-86 290.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ71863.1 - 5.5e-11 43.2 0.0 1.9e-10 41.5 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EEQ71863.1 - 0.0005 18.7 0.0 0.0018 16.8 0.0 1.7 2 0 0 2 2 2 1 GH3 auxin-responsive promoter PSCyt1 PF07635.6 EEQ71863.1 - 0.083 13.2 0.0 14 6.0 0.0 2.7 2 0 0 2 2 2 0 Planctomycete cytochrome C G-patch PF01585.18 EEQ71864.1 - 3.4e-10 39.5 1.5 6.8e-10 38.5 1.0 1.5 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 EEQ71864.1 - 3.6e-06 26.7 0.1 6.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEQ71864.1 - 6.2e-05 22.5 0.5 0.00014 21.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ71864.1 - 0.00084 19.2 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 EEQ71864.1 - 0.2 11.5 3.5 0.092 12.6 0.3 2.1 2 0 0 2 2 2 0 DExH-box splicing factor binding site FAD_binding_3 PF01494.14 EEQ71866.1 - 2.7e-80 270.0 0.0 3.3e-80 269.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EEQ71866.1 - 0.00013 22.3 0.0 0.094 13.1 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEQ71866.1 - 0.0002 21.3 0.0 0.00069 19.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EEQ71866.1 - 0.00057 18.6 0.0 0.00089 17.9 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase DAO PF01266.19 EEQ71866.1 - 0.0059 15.5 0.0 0.058 12.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEQ71866.1 - 0.025 14.4 0.0 0.04 13.7 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EEQ71866.1 - 0.027 13.2 0.0 0.12 11.2 0.0 1.8 1 1 0 1 1 1 0 Squalene epoxidase FAD_binding_2 PF00890.19 EEQ71866.1 - 0.036 12.9 0.0 0.78 8.5 0.0 2.5 3 0 0 3 3 3 0 FAD binding domain HI0933_like PF03486.9 EEQ71866.1 - 0.044 12.2 0.0 0.086 11.2 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 EEQ71866.1 - 0.045 12.6 0.1 0.073 11.9 0.1 1.4 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 EEQ71866.1 - 0.069 12.9 0.8 0.25 11.0 0.1 2.3 2 1 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_11 PF14833.1 EEQ71867.1 - 1.1e-38 131.9 3.4 9.7e-26 90.2 0.1 2.3 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EEQ71867.1 - 2.2e-38 131.6 0.3 4.1e-38 130.7 0.2 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EEQ71867.1 - 6.1e-05 22.7 0.1 0.0001 22.0 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EEQ71867.1 - 0.0012 19.1 0.1 0.0035 17.7 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 EEQ71867.1 - 0.0015 17.9 0.0 0.51 9.6 0.0 2.3 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HET PF06985.6 EEQ71868.1 - 3.7e-22 78.9 0.1 5.5e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1601 PF07671.6 EEQ71869.1 - 0.087 12.4 0.0 0.47 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1601) Acetyltransf_1 PF00583.19 EEQ71873.1 - 0.13 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Ctr PF04145.10 EEQ71875.1 - 0.0089 16.0 0.2 0.011 15.8 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family UPF0542 PF15086.1 EEQ71875.1 - 0.022 14.4 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 DUF202 PF02656.10 EEQ71875.1 - 0.023 14.9 0.3 0.027 14.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF202) PgaD PF13994.1 EEQ71875.1 - 0.025 14.0 0.2 0.03 13.8 0.1 1.0 1 0 0 1 1 1 0 PgaD-like protein DUF1109 PF06532.6 EEQ71875.1 - 0.043 13.2 0.3 0.047 13.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1109) DUF3404 PF11884.3 EEQ71875.1 - 0.082 11.7 0.2 0.081 11.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) DUF2149 PF09919.4 EEQ71875.1 - 0.094 12.8 0.3 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) SCIMP PF15050.1 EEQ71875.1 - 0.099 12.5 1.6 0.12 12.2 1.1 1.1 1 0 0 1 1 1 0 SCIMP protein Tad PF13400.1 EEQ71875.1 - 0.16 12.0 0.9 0.23 11.5 0.6 1.3 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like RTA1 PF04479.8 EEQ71877.1 - 1.7e-42 145.4 6.1 2.3e-42 145.0 4.3 1.1 1 0 0 1 1 1 1 RTA1 like protein Git3 PF11710.3 EEQ71878.1 - 2.1e-29 102.5 13.6 4.1e-29 101.6 9.4 1.5 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EEQ71878.1 - 2.7e-09 36.6 0.2 1.6e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 EEQ71878.1 - 6.2e-06 25.5 8.7 6.2e-06 25.5 6.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 EEQ71878.1 - 1.6e-05 23.9 10.5 2.7e-05 23.2 7.3 1.4 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor Fungal_trans PF04082.13 EEQ71879.1 - 7.7e-21 74.1 1.5 1.3e-20 73.4 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ71879.1 - 1.2e-08 34.7 10.5 2.2e-08 33.8 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.7 EEQ71879.1 - 0.00037 20.0 6.4 0.00087 18.8 4.5 1.6 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat APH PF01636.18 EEQ71881.1 - 0.00075 19.2 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family HhH-GPD PF00730.20 EEQ71883.1 - 8.2e-09 35.7 0.0 1e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein G_glu_transpept PF01019.16 EEQ71884.1 - 6.6e-161 536.2 0.0 7.6e-161 536.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase R3H PF01424.17 EEQ71885.1 - 3.7e-08 32.9 0.0 8.8e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 EEQ71885.1 - 0.00019 21.2 192.0 0.0026 17.6 11.1 12.9 12 1 0 12 12 12 7 NF-X1 type zinc finger zf-LYAR PF08790.6 EEQ71886.1 - 2.3e-05 23.9 15.1 7.8e-05 22.2 0.0 3.2 3 0 0 3 3 3 2 LYAR-type C2HC zinc finger DUF3597 PF12200.3 EEQ71886.1 - 3.7 7.9 9.3 4.8 7.5 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Methyltransf_23 PF13489.1 EEQ71887.1 - 9.4e-20 70.9 0.0 1.4e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ71887.1 - 9.6e-11 42.2 0.0 1.7e-09 38.2 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ71887.1 - 4.6e-08 33.4 0.0 9.4e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ71887.1 - 5.3e-08 32.5 0.0 8.5e-07 28.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ71887.1 - 2.1e-06 28.1 0.0 1.4e-05 25.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ71887.1 - 1.1e-05 25.7 0.0 3.6e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ71887.1 - 0.0086 16.0 0.0 0.037 14.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EEQ71887.1 - 0.024 14.6 0.0 0.056 13.4 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase CsoSCA PF08936.5 EEQ71887.1 - 0.15 10.4 0.0 0.18 10.1 0.0 1.1 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase Evr1_Alr PF04777.8 EEQ71890.1 - 2.5e-27 94.5 0.2 3.9e-27 93.9 0.2 1.3 1 0 0 1 1 1 1 Erv1 / Alr family MFS_1 PF07690.11 EEQ71891.1 - 8.7e-51 172.6 51.1 1.1e-49 169.0 24.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ71891.1 - 1.7e-05 23.5 30.4 0.00011 20.8 20.8 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter Patatin PF01734.17 EEQ71893.1 - 4.1e-25 88.9 0.1 1e-24 87.6 0.0 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase NB-ARC PF00931.17 EEQ71893.1 - 2e-09 36.7 0.0 3.3e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EEQ71893.1 - 0.0001 22.3 0.0 0.00071 19.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain TPR_10 PF13374.1 EEQ71893.1 - 0.00088 19.1 0.4 7.2 6.6 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ71893.1 - 0.0014 18.8 3.8 2.7 8.4 0.1 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat AAA_22 PF13401.1 EEQ71893.1 - 0.002 18.2 0.0 0.0071 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain TPR_12 PF13424.1 EEQ71893.1 - 0.0027 17.6 2.1 1.5 8.8 0.1 4.2 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ71893.1 - 0.0064 17.1 0.2 0.81 10.4 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat AAA PF00004.24 EEQ71893.1 - 0.018 15.2 0.0 0.049 13.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EEQ71893.1 - 0.046 13.1 0.4 0.1 12.0 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein ArsA_ATPase PF02374.10 EEQ71893.1 - 0.061 12.3 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase adh_short PF00106.20 EEQ71894.1 - 6.2e-30 104.3 2.7 7.6e-30 104.0 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ71894.1 - 2.5e-27 96.1 0.0 3.1e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ71894.1 - 1.6e-15 57.2 0.6 2.2e-15 56.7 0.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEQ71894.1 - 0.0005 19.5 0.1 0.00093 18.6 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EEQ71894.1 - 0.034 13.9 1.9 0.14 11.9 0.3 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Phage_ASH PF10554.4 EEQ71894.1 - 0.039 14.2 0.1 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 Ash protein family PTCB-BRCT PF12738.2 EEQ71895.1 - 1.4e-13 50.5 0.0 3.1e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EEQ71895.1 - 1.2e-07 31.8 0.0 2.1e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.3 EEQ71895.1 - 0.00055 19.6 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.16 EEQ71895.1 - 0.0023 18.0 0.0 0.005 16.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain ERCC4 PF02732.10 EEQ71896.1 - 7.7e-24 84.0 0.0 2.4e-23 82.4 0.0 1.9 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.1 EEQ71896.1 - 0.0034 17.5 0.0 0.0088 16.1 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.18 EEQ71896.1 - 0.02 14.5 0.4 0.11 12.2 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif eIF-1a PF01176.14 EEQ71897.1 - 1.3e-28 98.2 0.1 1.8e-28 97.7 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 WH1 PF00568.18 EEQ71900.1 - 4.2e-28 97.2 0.0 6.8e-28 96.6 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 EEQ71900.1 - 1.2e-05 24.7 0.4 2.5e-05 23.7 0.3 1.5 1 0 0 1 1 1 1 WH2 motif CorA PF01544.13 EEQ71901.1 - 7.3e-07 28.4 0.0 1.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Peptidase_C58 PF03543.9 EEQ71901.1 - 0.16 11.4 7.5 0.67 9.4 3.8 2.2 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen RHH_3 PF12651.2 EEQ71901.1 - 0.34 10.6 2.3 0.48 10.1 0.2 2.1 2 0 0 2 2 2 0 Ribbon-helix-helix domain LIM PF00412.17 EEQ71902.1 - 4.6e-20 71.4 46.5 7.9e-13 48.2 3.3 5.4 4 1 1 5 5 5 3 LIM domain Nucleoporin_FG PF13634.1 EEQ71902.1 - 0.17 12.0 5.1 6.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Nucleoporin FG repeat region Lipase_GDSL PF00657.17 EEQ71903.1 - 2e-15 57.2 0.0 3.3e-15 56.5 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EEQ71903.1 - 8.5e-05 22.7 0.0 0.0002 21.5 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Amidohydro_2 PF04909.9 EEQ71904.1 - 3.8e-07 29.9 0.1 6.5e-07 29.1 0.1 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EEQ71904.1 - 1.5e-05 24.8 0.0 2.7e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EEQ71904.1 - 2.9e-05 24.2 0.3 5.3e-05 23.3 0.2 1.4 1 1 0 1 1 1 1 Amidohydrolase SEN1_N PF12726.2 EEQ71906.1 - 8.6e-232 771.2 6.6 1.1e-231 770.8 4.6 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EEQ71906.1 - 6.5e-69 232.0 1.4 6.5e-69 232.0 1.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EEQ71906.1 - 4.3e-61 205.7 0.0 8.5e-61 204.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ71906.1 - 1.5e-10 40.7 0.1 4.5e-10 39.1 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EEQ71906.1 - 3.1e-09 36.7 0.7 6.4e-06 25.8 0.1 2.6 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.16 EEQ71906.1 - 4.5e-08 32.7 0.1 2.6e-06 26.9 0.0 2.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 EEQ71906.1 - 1.3e-07 31.3 0.1 0.074 12.5 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase zf-CCHC PF00098.18 EEQ71906.1 - 0.00054 19.7 0.9 0.00054 19.7 0.6 3.4 3 0 0 3 3 3 2 Zinc knuckle DEAD PF00270.24 EEQ71906.1 - 0.00091 18.7 0.4 0.016 14.7 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_25 PF13481.1 EEQ71906.1 - 0.018 14.4 0.0 0.045 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EEQ71906.1 - 0.025 14.4 0.1 0.13 12.1 0.0 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit T2SE PF00437.15 EEQ71906.1 - 0.056 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein zf-CCHC_4 PF14392.1 EEQ71906.1 - 0.39 10.4 16.4 1.1 8.9 1.0 3.8 2 1 1 3 3 3 0 Zinc knuckle HAD PF12710.2 EEQ71907.1 - 1.6e-13 51.2 0.0 3.5e-13 50.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EEQ71907.1 - 3.1e-12 46.0 0.0 6.3e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EEQ71907.1 - 3.3e-12 47.3 0.7 1.5e-10 41.8 0.5 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ71907.1 - 7.5e-12 45.0 0.0 1.9e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEQ71907.1 - 0.0097 15.5 0.3 0.02 14.4 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-UBP PF02148.14 EEQ71907.1 - 0.11 12.6 0.2 0.28 11.3 0.2 1.6 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Metallophos_2 PF12850.2 EEQ71908.1 - 0.0012 18.6 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EEQ71908.1 - 0.0048 16.3 0.2 0.0068 15.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Adeno_VII PF03228.9 EEQ71909.1 - 0.00072 20.1 0.3 0.0025 18.3 0.0 2.1 2 0 0 2 2 2 1 Adenoviral core protein VII vATP-synt_E PF01991.13 EEQ71910.1 - 6.8e-53 178.8 14.6 2e-52 177.3 10.1 1.6 1 1 0 1 1 1 1 ATP synthase (E/31 kDa) subunit BrkDBD PF09607.5 EEQ71910.1 - 0.05 13.1 0.1 0.086 12.4 0.1 1.4 1 0 0 1 1 1 0 Brinker DNA-binding domain Mg_trans_NIPA PF05653.9 EEQ71911.1 - 3.5e-12 45.8 9.5 7.1e-09 35.0 0.7 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 EEQ71911.1 - 2.8e-05 24.1 0.5 2.8e-05 24.1 0.3 2.8 3 0 0 3 3 3 2 EamA-like transporter family Multi_Drug_Res PF00893.14 EEQ71911.1 - 1.6 9.2 7.9 2.6 8.5 0.4 2.6 2 0 0 2 2 2 0 Small Multidrug Resistance protein SRF-TF PF00319.13 EEQ71912.1 - 1.6e-23 81.6 0.2 2.2e-23 81.1 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ribosomal_60s PF00428.14 EEQ71912.1 - 0.48 10.8 4.8 1.4 9.4 3.3 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein HP_OMP PF01856.12 EEQ71913.1 - 0.092 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Helicobacter outer membrane protein DUF3723 PF12520.3 EEQ71914.1 - 1.2e-114 383.5 2.8 2.2e-96 323.3 0.7 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) Pkinase PF00069.20 EEQ71915.1 - 8.7e-38 129.9 0.0 1.4e-37 129.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ71915.1 - 2.3e-13 49.8 0.0 4e-12 45.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EEQ71915.1 - 0.054 12.2 0.0 0.082 11.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase BESS PF02944.15 EEQ71915.1 - 0.055 13.0 0.2 0.055 13.0 0.1 1.9 2 0 0 2 2 2 0 BESS motif APH PF01636.18 EEQ71915.1 - 0.1 12.3 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Fungal_trans_2 PF11951.3 EEQ71916.1 - 0.00072 18.2 1.0 0.00072 18.2 0.7 2.3 1 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ71916.1 - 0.00085 19.1 1.6 0.0017 18.2 1.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEV_ORF1 PF02444.11 EEQ71916.1 - 0.02 15.1 0.2 0.052 13.7 0.2 1.7 1 0 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) Neurensin PF14927.1 EEQ71916.1 - 0.089 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Neurensin Tetraspannin PF00335.15 EEQ71917.1 - 1.6e-08 34.0 7.0 2.3e-08 33.6 4.8 1.1 1 0 0 1 1 1 1 Tetraspanin family Sgf11 PF08209.6 EEQ71918.1 - 3.5e-10 39.0 2.7 5.5e-10 38.3 0.1 2.2 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 EEQ71918.1 - 0.038 13.6 0.6 0.038 13.6 0.4 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 EEQ71918.1 - 0.79 10.1 3.1 1.7 9.0 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double domain Acetyltransf_1 PF00583.19 EEQ71919.1 - 9.5e-06 25.5 0.0 0.00014 21.8 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family NAD_binding_6 PF08030.7 EEQ71920.1 - 7.5e-19 68.1 0.0 4.5e-18 65.6 0.0 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EEQ71920.1 - 6.5e-17 61.7 6.4 6.5e-17 61.7 4.5 2.3 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EEQ71920.1 - 2.4e-14 53.0 0.0 7.5e-14 51.4 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 EEQ71920.1 - 0.002 18.6 0.0 3.1 8.4 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain BAF1_ABF1 PF04684.8 EEQ71920.1 - 4.5 6.0 6.0 7.6 5.2 4.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Acetyltransf_7 PF13508.1 EEQ71922.1 - 0.0065 16.6 0.0 0.064 13.4 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEQ71922.1 - 0.0087 16.0 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family RNase_PH PF01138.16 EEQ71923.1 - 3e-18 66.4 2.8 2.5e-16 60.2 2.0 2.3 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Peptidase_A22B PF04258.8 EEQ71924.1 - 1.2e-56 192.4 0.6 5e-56 190.3 0.4 1.9 1 1 0 1 1 1 1 Signal peptide peptidase PBP1_TM PF14812.1 EEQ71924.1 - 0.0019 18.4 0.8 0.0019 18.4 0.5 3.8 4 0 0 4 4 4 1 Transmembrane domain of transglycosylase PBP1 at N-terminal TRAP_alpha PF03896.11 EEQ71924.1 - 0.012 14.6 12.1 0.39 9.6 0.0 3.3 3 0 0 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit FAM176 PF14851.1 EEQ71924.1 - 0.014 15.0 0.1 0.014 15.0 0.0 4.5 2 1 2 4 4 4 0 FAM176 family UBACT PF02134.16 EEQ71924.1 - 0.13 11.8 0.2 0.26 10.8 0.2 1.4 1 0 0 1 1 1 0 Repeat in ubiquitin-activating (UBA) protein Plasmodium_Vir PF05795.6 EEQ71924.1 - 1.4 8.0 14.6 6.4 5.8 0.0 2.4 2 0 0 2 2 2 0 Plasmodium vivax Vir protein UPF0233 PF06781.7 EEQ71924.1 - 2.4 7.8 0.0 2.4 7.8 0.0 3.4 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0233) Pro_isomerase PF00160.16 EEQ71925.1 - 2.9e-44 150.9 0.0 3.5e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GDI PF00996.13 EEQ71926.1 - 2e-42 145.0 0.0 2.6e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Fringe PF02434.11 EEQ71927.1 - 4.7e-07 29.2 0.0 1.3e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Fringe-like DUF604 PF04646.7 EEQ71927.1 - 2.6e-05 23.5 0.0 3.6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 DUF3845 PF12956.2 EEQ71927.1 - 0.1 12.0 0.3 0.5 9.7 0.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure zf-C2HC5 PF06221.8 EEQ71928.1 - 2.7e-23 81.4 6.2 4.3e-23 80.8 4.3 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Poty_PP PF08440.5 EEQ71928.1 - 0.1 11.6 1.0 0.2 10.6 0.7 1.4 1 0 0 1 1 1 0 Potyviridae polyprotein Ribosomal_60s PF00428.14 EEQ71928.1 - 0.25 11.7 11.7 0.6 10.5 7.7 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Mucin PF01456.12 EEQ71928.1 - 0.27 10.9 23.8 0.3 10.8 9.8 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Paramyxo_C PF01692.13 EEQ71928.1 - 1.1 8.7 11.0 3.2 7.3 0.1 2.2 2 0 0 2 2 2 0 Paramyxovirus non-structural protein c HAUS6_N PF14661.1 EEQ71928.1 - 1.3 8.2 8.5 0.05 12.9 1.1 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Secretin_N_2 PF07655.8 EEQ71928.1 - 5.2 7.5 27.3 0.74 10.2 7.7 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain Hexokinase_1 PF00349.16 EEQ71929.1 - 5.1e-67 225.1 0.1 1.5e-66 223.6 0.0 1.8 1 1 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EEQ71929.1 - 7.3e-67 225.1 0.0 1.1e-66 224.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF1690 PF07956.6 EEQ71930.1 - 9.8e-30 103.3 6.8 1.5e-14 54.1 0.0 2.1 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) K167R PF08065.7 EEQ71930.1 - 0.00064 19.7 0.1 0.00064 19.7 0.1 2.0 2 1 0 2 2 2 1 K167R (NUC007) repeat HrpA_pilin PF09589.5 EEQ71930.1 - 0.38 11.1 6.6 1.3 9.4 1.3 2.1 1 1 1 2 2 2 0 HrpA pilus formation protein Terminase_2 PF03592.11 EEQ71930.1 - 1.3 9.2 5.8 12 6.2 0.5 2.1 1 1 1 2 2 2 0 Terminase small subunit ATP-synt_B PF00430.13 EEQ71930.1 - 3.1 7.6 9.8 1.7 8.4 3.9 2.1 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) POP1 PF06978.6 EEQ71931.1 - 2.6e-65 219.5 10.1 2.6e-65 219.5 7.0 2.5 3 1 0 3 3 3 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EEQ71931.1 - 1.7e-30 104.7 0.3 4.9e-30 103.2 0.2 1.9 1 0 0 1 1 1 1 POPLD (NUC188) domain Redoxin PF08534.5 EEQ71932.1 - 8.5e-39 132.4 0.0 9.6e-39 132.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EEQ71932.1 - 5.3e-12 45.5 0.0 6.9e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DAO PF01266.19 EEQ71935.1 - 4.5e-10 38.9 0.0 1e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Fasciclin PF02469.17 EEQ71936.1 - 7.9e-42 142.2 0.0 1.4e-23 83.2 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Nucleoplasmin PF03066.10 EEQ71936.1 - 0.084 12.3 1.9 0.16 11.4 1.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin NLPC_P60 PF00877.14 EEQ71937.1 - 1.5e-10 40.8 0.0 5.1e-10 39.1 0.0 1.8 1 1 0 1 1 1 1 NlpC/P60 family TSGP1 PF07771.6 EEQ71937.1 - 0.0095 15.8 12.4 1.1 9.0 9.9 2.3 2 0 0 2 2 2 1 Tick salivary peptide group 1 Chordopox_A33R PF05966.7 EEQ71937.1 - 0.21 10.3 0.8 0.54 9.0 0.5 1.7 1 0 0 1 1 1 0 Chordopoxvirus A33R protein DUF2147 PF09917.4 EEQ71937.1 - 0.31 11.3 3.9 0.61 10.3 2.7 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2147) p450 PF00067.17 EEQ71938.1 - 2.3e-05 23.1 0.1 3.2e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PhoD PF09423.5 EEQ71939.1 - 8.7e-159 528.8 0.3 1e-158 528.6 0.2 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase Pkinase PF00069.20 EEQ71940.1 - 4.1e-72 242.4 0.0 6.2e-72 241.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ71940.1 - 8.9e-34 116.7 0.0 1.2e-30 106.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EEQ71940.1 - 0.0016 18.2 0.0 0.0053 16.5 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EEQ71940.1 - 0.0045 15.9 0.0 0.0099 14.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEQ71940.1 - 0.0047 16.0 0.0 0.009 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EEQ71940.1 - 0.017 14.6 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase 4HBT PF03061.17 EEQ71943.1 - 3.4e-11 43.1 0.0 6.3e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EEQ71943.1 - 0.022 14.7 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) UCH PF00443.24 EEQ71944.1 - 3e-55 187.2 0.0 3.6e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEQ71944.1 - 1.2e-16 60.9 0.2 5.3e-16 58.9 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EEQ71944.1 - 1.7e-10 40.1 0.0 3.9e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family IMD PF08397.6 EEQ71944.1 - 0.02 14.1 5.4 0.27 10.5 0.0 2.4 2 0 0 2 2 2 0 IRSp53/MIM homology domain ARPC4 PF05856.7 EEQ71945.1 - 4.9e-74 247.3 4.7 5.5e-74 247.1 3.3 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) RRM_6 PF14259.1 EEQ71946.1 - 0.065 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TYW3 PF02676.9 EEQ71947.1 - 2.5e-67 226.0 0.0 3e-67 225.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF2461 PF09365.5 EEQ71948.1 - 2.6e-76 255.7 2.8 5.3e-76 254.7 0.2 2.1 2 0 0 2 2 2 1 Conserved hypothetical protein (DUF2461) Zn_clus PF00172.13 EEQ71953.1 - 7.3e-09 35.3 7.5 1.1e-08 34.8 5.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain V-ATPase_G PF03179.10 EEQ71954.1 - 0.0087 16.3 0.2 0.011 16.0 0.1 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit SPOB_a PF14689.1 EEQ71954.1 - 0.17 11.4 0.7 0.27 10.8 0.3 1.6 1 1 1 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain WD40 PF00400.27 EEQ71955.1 - 2.4e-10 39.8 21.8 3.2e-05 23.6 0.0 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat RWD PF05773.17 EEQ71955.1 - 0.0011 18.7 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-C3HC4_2 PF13923.1 EEQ71955.1 - 0.36 10.8 16.9 0.035 14.1 6.8 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) UQ_con PF00179.21 EEQ71956.1 - 9e-46 154.7 0.0 1.1e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEQ71956.1 - 3e-05 23.7 0.0 3.9e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EEQ71956.1 - 0.0042 16.7 0.0 0.0063 16.1 0.0 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 EEQ71956.1 - 0.027 14.3 0.1 0.033 14.0 0.1 1.3 1 1 0 1 1 1 0 RWD domain DUF3000 PF11452.3 EEQ71956.1 - 0.11 11.6 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3000) Ribosomal_L24e PF01246.15 EEQ71957.1 - 5.5e-31 106.2 0.5 5.5e-31 106.2 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e Ribosomal_S30 PF04758.9 EEQ71958.1 - 1e-28 98.8 7.2 1.2e-28 98.6 5.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 HSDR_N_2 PF13588.1 EEQ71960.1 - 0.015 15.1 0.0 3.7 7.3 0.0 2.4 1 1 1 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Sod_Cu PF00080.15 EEQ71961.1 - 6.4e-14 52.3 0.0 8.9e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 EEQ71961.1 - 3.1e-07 30.4 0.0 5.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain TPR_11 PF13414.1 EEQ71962.1 - 6.4e-15 54.5 5.4 5.3e-08 32.3 0.0 3.2 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 EEQ71962.1 - 1.1e-12 46.8 4.0 0.00029 20.5 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ71962.1 - 7.8e-12 44.2 4.3 0.00035 20.0 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ71962.1 - 1.1e-07 31.7 0.3 4.5e-05 23.3 0.0 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ71962.1 - 1.1e-07 31.1 0.9 0.026 14.2 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ71962.1 - 4.8e-06 26.6 0.2 9.6 6.9 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat PB1 PF00564.19 EEQ71962.1 - 9e-06 25.2 0.1 2e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 PB1 domain TPR_16 PF13432.1 EEQ71962.1 - 0.00013 22.4 1.1 0.0066 17.1 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ71962.1 - 0.00016 21.2 0.4 0.0018 17.8 0.1 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ71962.1 - 0.00043 20.2 0.2 0.037 14.2 0.0 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ71962.1 - 0.0024 17.6 0.1 1.1 9.2 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ71962.1 - 0.0076 16.7 0.2 0.62 10.8 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EEQ71962.1 - 0.85 9.8 3.3 2.8 8.1 0.1 2.5 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Syntaxin-18_N PF10496.4 EEQ71963.1 - 3e-20 71.8 1.4 3e-20 71.8 1.0 2.3 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 EEQ71963.1 - 0.0002 20.9 2.5 0.00035 20.2 0.9 2.1 2 0 0 2 2 2 1 SNARE domain HTH_33 PF13592.1 EEQ71963.1 - 0.0062 16.0 0.4 2.6 7.6 0.0 3.3 2 1 1 3 3 3 1 Winged helix-turn helix Acyl_transf_3 PF01757.17 EEQ71964.1 - 5.7e-23 81.2 28.2 7.3e-23 80.9 19.5 1.1 1 0 0 1 1 1 1 Acyltransferase family Aminotran_1_2 PF00155.16 EEQ71965.1 - 1.3e-82 277.6 0.0 1.5e-82 277.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II zf-RING_2 PF13639.1 EEQ71966.1 - 3.5e-14 52.3 4.8 6e-14 51.5 3.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EEQ71966.1 - 1.9e-07 30.6 3.3 3.1e-07 29.9 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ71966.1 - 3e-07 30.3 5.2 5.1e-07 29.6 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEQ71966.1 - 5.8e-07 29.5 0.9 1.2e-06 28.5 0.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EEQ71966.1 - 8.2e-06 25.4 2.1 1.3e-05 24.7 1.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EEQ71966.1 - 3.5e-05 23.3 1.4 6.3e-05 22.5 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEQ71966.1 - 0.001 18.8 1.4 0.0019 17.9 1.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EEQ71966.1 - 0.0074 15.8 3.2 0.014 15.0 2.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EEQ71966.1 - 0.18 11.8 2.7 0.3 11.1 1.9 1.4 1 0 0 1 1 1 0 RING-like domain Rad50_zn_hook PF04423.9 EEQ71966.1 - 0.21 11.0 0.2 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C3HC4_4 PF15227.1 EEQ71966.1 - 3.9 7.4 5.8 7 6.6 4.0 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING MS_channel PF00924.13 EEQ71967.1 - 3e-19 69.1 1.5 5e-19 68.4 1.0 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EEQ71967.1 - 0.0013 17.8 0.1 0.0029 16.7 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EEQ71967.1 - 0.028 14.2 0.0 0.087 12.7 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.1 EEQ71967.1 - 0.029 14.5 0.1 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.1 EEQ71967.1 - 0.069 12.5 0.3 0.3 10.5 0.0 2.2 3 0 0 3 3 3 0 EF hand Mgm101p PF06420.7 EEQ71968.1 - 2.2e-92 307.0 0.0 3e-92 306.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 MSP1_C PF07462.6 EEQ71968.1 - 0.17 10.2 2.1 0.21 9.9 1.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus CHCH PF06747.8 EEQ71969.1 - 1.2e-07 31.3 8.3 1.9e-07 30.8 5.8 1.3 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.8 EEQ71969.1 - 0.087 12.8 2.8 0.13 12.3 1.9 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 EEQ71969.1 - 0.21 11.3 7.7 19 5.1 0.4 2.2 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like BPL_N PF09825.4 EEQ71970.1 - 7.6e-132 439.5 5.8 1.9e-131 438.1 1.4 2.4 2 1 0 2 2 2 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EEQ71970.1 - 7.7e-20 71.1 0.0 1.4e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family NRDE PF05742.7 EEQ71971.1 - 9.1e-46 156.3 0.0 2.4e-45 154.9 0.0 1.6 1 1 0 1 1 1 1 NRDE protein MFS_1 PF07690.11 EEQ71972.1 - 5.2e-14 51.7 49.7 1.3e-09 37.3 13.3 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EEQ71972.1 - 3.9e-07 28.6 20.8 5.6e-07 28.1 14.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TB2_DP1_HVA22 PF03134.14 EEQ71973.1 - 1e-28 98.8 8.2 1.6e-28 98.2 5.7 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family IncA PF04156.9 EEQ71974.1 - 0.0011 18.6 8.8 0.0011 18.6 6.1 2.4 2 1 1 3 3 3 1 IncA protein Zip PF02535.17 EEQ71974.1 - 0.14 11.1 3.6 0.18 10.8 2.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter BBS2_C PF14782.1 EEQ71974.1 - 4.2 5.8 6.3 0.26 9.8 0.8 1.5 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal Rhodanese PF00581.15 EEQ71975.1 - 2.1e-11 44.1 0.0 2.4e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_28 PF02636.12 EEQ71976.1 - 2.2e-83 279.5 0.0 2.8e-83 279.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RRM_1 PF00076.17 EEQ71977.1 - 0.0046 16.5 0.0 0.0083 15.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ71977.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ71977.1 - 0.044 13.6 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Serglycin PF04360.7 EEQ71977.1 - 1.3 8.7 5.0 1.5 8.5 0.1 2.6 3 0 0 3 3 3 0 Serglycin CENP-B_dimeris PF09026.5 EEQ71978.1 - 0.077 13.2 6.3 0.1 12.8 4.4 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 EEQ71978.1 - 0.13 12.6 9.7 0.19 12.0 6.7 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.9 EEQ71978.1 - 0.47 8.4 2.5 0.44 8.5 1.7 1.0 1 0 0 1 1 1 0 CDC45-like protein MIF4G PF02854.14 EEQ71980.1 - 3.6e-43 147.4 0.0 6.9e-43 146.4 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EEQ71980.1 - 6.3e-22 77.2 1.9 6.3e-22 77.2 1.3 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 Ribosomal_S21 PF01165.15 EEQ71981.1 - 2.6e-10 39.5 5.1 4.1e-10 38.9 3.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 PBAN PF05874.6 EEQ71981.1 - 0.0093 15.3 0.3 0.014 14.7 0.2 1.3 1 0 0 1 1 1 1 Pheromone biosynthesis activating neuropeptide (PBAN) Leu_Phe_trans PF03588.9 EEQ71981.1 - 0.015 14.4 1.0 0.021 13.9 0.7 1.2 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase BLVR PF06375.6 EEQ71983.1 - 3.1 7.6 10.7 0.62 9.8 4.9 1.8 1 1 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) PGI PF00342.14 EEQ71984.1 - 1.2e-219 729.7 0.6 1.3e-219 729.5 0.4 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase PT PF04886.7 EEQ71986.1 - 0.35 10.2 89.3 4.4e+03 -3.0 4.1 4.7 2 1 0 2 2 2 0 PT repeat PWI PF01480.12 EEQ71987.1 - 1e-09 38.3 0.7 2.9e-09 36.9 0.5 1.8 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 EEQ71987.1 - 0.00098 18.7 0.0 0.0023 17.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ71987.1 - 0.011 15.7 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) NMO PF03060.10 EEQ71988.1 - 8e-70 235.5 0.3 9.5e-70 235.3 0.2 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EEQ71988.1 - 1.1e-08 34.4 0.1 2.2e-07 30.1 0.0 2.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EEQ71988.1 - 1.4e-06 27.4 0.5 2.6e-06 26.5 0.3 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 EEQ71988.1 - 3.3e-05 22.9 0.1 5.8e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 EEQ71988.1 - 0.0018 17.2 0.5 0.0033 16.4 0.3 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Aminotran_5 PF00266.14 EEQ71989.1 - 1e-38 133.0 0.0 1.4e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Pterin_bind PF00809.17 EEQ71991.1 - 1.4e-60 204.2 0.3 2.2e-59 200.3 0.0 2.5 2 1 0 2 2 2 1 Pterin binding enzyme HPPK PF01288.15 EEQ71991.1 - 7e-40 135.6 0.0 1.6e-39 134.5 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) ArfGap PF01412.13 EEQ71992.1 - 4.4e-35 119.9 0.3 7.8e-35 119.1 0.2 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TIM21 PF08294.6 EEQ71993.1 - 9.2e-43 145.3 0.0 1.2e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 EEQ71993.1 - 1.2e-05 24.8 0.0 2.7e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 CIA30 PF08547.7 EEQ71993.1 - 0.0077 16.1 0.0 0.022 14.6 0.0 1.7 1 1 1 2 2 2 1 Complex I intermediate-associated protein 30 (CIA30) Peptidase_S10 PF00450.17 EEQ71995.1 - 8.8e-17 61.3 0.6 1.4e-13 50.8 0.0 2.2 2 0 0 2 2 2 2 Serine carboxypeptidase eIF3g PF12353.3 EEQ71996.1 - 5.8e-47 158.7 1.8 1.1e-46 157.9 1.3 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EEQ71996.1 - 2.5e-16 59.0 0.1 4.1e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ71996.1 - 3.5e-12 46.1 0.1 6.8e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ71996.1 - 2.9e-07 30.2 0.1 5.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NDT80_PhoG PF05224.7 EEQ71998.1 - 4.9e-42 144.0 0.0 9e-42 143.1 0.0 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family YfhO PF09586.5 EEQ71998.1 - 0.052 11.5 1.2 0.08 10.9 0.8 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO AMP-binding PF00501.23 EEQ72000.1 - 1.2e-79 267.7 0.0 2e-79 266.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Methyltransf_16 PF10294.4 EEQ72004.1 - 7e-13 48.3 0.6 9.9e-08 31.6 0.0 2.5 2 1 1 3 3 3 2 Putative methyltransferase MTS PF05175.9 EEQ72004.1 - 0.031 13.6 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Macro_2 PF14519.1 EEQ72005.1 - 0.0088 15.1 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Macro-like domain Peptidase_S46 PF10459.4 EEQ72006.1 - 0.21 9.9 5.4 0.25 9.7 3.8 1.0 1 0 0 1 1 1 0 Peptidase S46 HSP70 PF00012.15 EEQ72007.1 - 1.1e-264 879.0 16.7 1.3e-264 878.7 11.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEQ72007.1 - 2.7e-13 49.2 8.8 3.5e-12 45.5 1.5 2.7 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.11 EEQ72007.1 - 0.00013 21.6 0.1 0.00032 20.3 0.1 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.6 EEQ72007.1 - 0.0037 16.2 5.3 0.16 10.9 0.1 3.3 2 1 1 3 3 3 1 StbA protein FtsA PF14450.1 EEQ72007.1 - 0.014 15.1 11.2 1.3 8.9 0.0 4.9 2 2 2 4 4 4 0 Cell division protein FtsA DUF4363 PF14276.1 EEQ72007.1 - 0.58 9.8 3.1 1.1 8.9 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Tom22 PF04281.8 EEQ72007.1 - 1.6 8.2 11.4 0.21 11.1 4.5 2.1 1 1 1 2 2 2 0 Mitochondrial import receptor subunit Tom22 Hydantoinase_A PF01968.13 EEQ72007.1 - 7.7 5.5 13.1 2.3 7.2 0.0 3.9 3 1 0 4 4 4 0 Hydantoinase/oxoprolinase DUF2415 PF10313.4 EEQ72008.1 - 1.9e-14 53.0 0.0 6.7e-14 51.2 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 EEQ72008.1 - 0.096 12.6 1.0 5.1 7.1 0.3 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat Choline_transpo PF04515.7 EEQ72010.1 - 1.1e-81 274.2 10.1 1.8e-81 273.4 7.0 1.4 1 0 0 1 1 1 1 Plasma-membrane choline transporter DSHCT PF08148.7 EEQ72011.1 - 3.3e-61 205.6 0.6 3.3e-61 205.6 0.4 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 EEQ72011.1 - 5.6e-20 71.5 0.0 1.1e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ72011.1 - 3.5e-06 26.7 0.0 8.1e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ72011.1 - 0.01 15.6 0.1 0.14 11.9 0.1 2.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit BRCA2 PF00634.13 EEQ72011.1 - 0.077 12.2 1.4 1.1 8.6 0.1 2.5 2 0 0 2 2 2 0 BRCA2 repeat IBN_N PF03810.14 EEQ72012.1 - 1.2e-14 53.9 1.5 1.4e-12 47.3 0.0 3.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.5 EEQ72012.1 - 1.2e-06 27.3 0.0 2.6e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Cse1 HEAT_2 PF13646.1 EEQ72012.1 - 1.9e-05 24.8 3.6 0.018 15.3 0.0 3.8 3 1 0 3 3 3 2 HEAT repeats DUF2435 PF10363.4 EEQ72012.1 - 0.001 18.8 0.3 0.0056 16.5 0.2 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) Xpo1 PF08389.7 EEQ72012.1 - 0.0015 18.4 2.0 0.065 13.1 0.0 3.9 4 0 0 4 4 4 1 Exportin 1-like protein Serglycin PF04360.7 EEQ72013.1 - 0.0022 17.7 5.3 0.0024 17.6 3.7 1.3 1 0 0 1 1 1 1 Serglycin RRM_1 PF00076.17 EEQ72014.1 - 3.4e-08 33.0 0.0 6.6e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ72014.1 - 9.9e-08 31.8 0.0 2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEQ72014.1 - 9.7e-05 22.0 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 EEQ72014.1 - 0.012 15.3 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Siah-Interact_N PF09032.6 EEQ72015.1 - 0.01 15.8 2.3 0.069 13.2 0.1 2.4 2 0 0 2 2 2 0 Siah interacting protein, N terminal DivIC PF04977.10 EEQ72015.1 - 0.028 13.9 1.5 0.053 13.0 0.1 1.9 2 0 0 2 2 2 0 Septum formation initiator Striatin PF08232.7 EEQ72015.1 - 0.033 14.4 2.5 3.2 8.0 0.1 2.5 2 0 0 2 2 2 0 Striatin family SlyX PF04102.7 EEQ72015.1 - 0.036 14.4 1.9 4.6 7.6 0.1 2.5 2 0 0 2 2 2 0 SlyX DegS PF05384.6 EEQ72015.1 - 0.11 11.7 3.0 0.13 11.4 0.3 1.9 2 0 0 2 2 2 0 Sensor protein DegS DUF2057 PF09829.4 EEQ72015.1 - 0.19 11.3 3.4 2.4 7.7 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Herpes_UL25 PF01499.11 EEQ72015.1 - 0.36 9.0 6.2 0.23 9.7 0.7 2.0 2 0 0 2 2 2 0 Herpesvirus UL25 family Tmemb_cc2 PF10267.4 EEQ72015.1 - 0.43 9.0 10.8 1.1 7.7 7.3 1.8 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Macoilin PF09726.4 EEQ72015.1 - 2.3 6.4 16.9 3.6 5.7 11.7 1.2 1 0 0 1 1 1 0 Transmembrane protein DbpA PF03880.10 EEQ72017.1 - 0.0016 18.0 0.0 0.0042 16.7 0.0 1.7 1 0 0 1 1 1 1 DbpA RNA binding domain RRM_5 PF13893.1 EEQ72017.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEQ72017.1 - 0.026 14.1 0.0 0.066 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 EEQ72019.1 - 1.1e-31 109.9 26.6 5.4e-30 104.2 14.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ72019.1 - 7.1e-11 41.3 4.5 7.1e-11 41.3 3.1 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 EEQ72019.1 - 0.08 11.0 3.0 0.28 9.2 1.3 2.0 1 1 0 2 2 2 0 Transmembrane secretion effector DUF2244 PF10003.4 EEQ72019.1 - 0.19 11.0 0.0 0.19 11.0 0.0 2.9 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) Kinetocho_Slk19 PF12709.2 EEQ72020.1 - 2.8e-22 78.5 6.9 2.8e-22 78.5 4.8 5.1 4 1 1 5 5 5 2 Central kinetochore-associated DBR1 PF05011.8 EEQ72020.1 - 0.73 9.7 12.1 0.021 14.7 1.3 3.1 3 1 1 4 4 4 0 Lariat debranching enzyme, C-terminal domain FAD_binding_3 PF01494.14 EEQ72021.1 - 1.4e-12 47.3 0.1 3.8e-12 45.9 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain PcfK PF14058.1 EEQ72021.1 - 0.014 15.5 0.1 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 PcfK-like protein NAD_binding_9 PF13454.1 EEQ72021.1 - 0.016 15.0 0.0 7.4 6.3 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding Peptidase_C21 PF05381.7 EEQ72021.1 - 0.026 14.6 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Tymovirus endopeptidase NAD_binding_8 PF13450.1 EEQ72021.1 - 0.037 14.0 0.4 0.14 12.2 0.0 2.2 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEQ72021.1 - 0.079 11.8 0.1 0.13 11.1 0.0 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Dynamin_N PF00350.18 EEQ72022.1 - 2.8e-31 108.6 0.0 5.8e-31 107.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EEQ72022.1 - 3.6e-19 68.6 0.0 8.7e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region GED PF02212.13 EEQ72022.1 - 2.7e-06 27.1 1.7 1.1e-05 25.1 0.0 2.7 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EEQ72022.1 - 7.3e-05 22.7 0.0 0.00047 20.1 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEQ72022.1 - 0.009 16.4 0.0 0.021 15.3 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EEQ72022.1 - 0.054 12.8 0.0 0.55 9.6 0.0 2.2 2 0 0 2 2 2 0 Ras family Fungal_trans PF04082.13 EEQ72024.1 - 4.2e-37 127.4 1.3 8.3e-37 126.4 0.9 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ72024.1 - 0.0021 17.9 18.1 0.0044 16.8 12.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S10 PF00450.17 EEQ72026.1 - 2.2e-90 303.8 1.5 2.3e-53 181.8 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase MFS_1 PF07690.11 EEQ72027.1 - 9.4e-16 57.4 30.8 1.5e-15 56.8 21.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EEQ72027.1 - 5.1e-10 39.0 3.2 5.1e-10 39.0 2.2 3.2 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 Amidohydro_4 PF13147.1 EEQ72028.1 - 2.7e-14 53.8 2.0 2.6e-12 47.3 1.4 3.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EEQ72028.1 - 4.7e-12 46.2 0.6 8e-06 25.7 0.0 3.1 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 EEQ72028.1 - 7.8e-06 25.3 0.1 1.7e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EEQ72028.1 - 0.00023 20.9 0.0 0.001 18.8 0.0 2.1 1 0 0 1 1 1 1 Amidohydrolase Hydrophobin PF01185.13 EEQ72029.1 - 3.8e-06 27.2 4.3 1.4e-05 25.4 3.0 1.8 1 1 0 1 1 1 1 Fungal hydrophobin GMC_oxred_N PF00732.14 EEQ72030.1 - 2.2e-51 174.7 0.0 2.8e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EEQ72030.1 - 2.1e-38 131.8 0.0 3.1e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EEQ72030.1 - 4.6e-06 25.7 0.4 0.00011 21.2 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEQ72030.1 - 9.1e-06 24.7 0.0 0.11 11.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EEQ72030.1 - 2.4e-05 23.4 0.0 3.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EEQ72030.1 - 9.7e-05 22.3 0.1 0.0003 20.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EEQ72030.1 - 0.0034 16.5 1.0 0.021 13.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase UPF0075 PF03702.9 EEQ72030.1 - 0.0038 16.1 0.0 0.0061 15.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) Trp_halogenase PF04820.9 EEQ72030.1 - 0.0054 15.4 0.0 0.0083 14.7 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EEQ72030.1 - 0.011 15.6 0.0 0.041 13.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEQ72030.1 - 0.059 13.1 0.1 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EEQ72030.1 - 0.094 12.7 0.1 5.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEQ72030.1 - 0.12 12.7 0.4 1.8 9.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.17 EEQ72033.1 - 1.6e-36 125.8 0.0 2.9e-35 121.6 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Aldedh PF00171.17 EEQ72034.1 - 1.2e-160 534.9 0.0 1.4e-160 534.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EEQ72034.1 - 0.12 11.6 0.0 8.2 5.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Glucosamine_iso PF01182.15 EEQ72035.1 - 1.5e-23 83.5 0.0 2.2e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sugar-bind PF04198.8 EEQ72035.1 - 0.049 12.5 0.0 0.079 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain Glyco_hydro_3 PF00933.16 EEQ72036.1 - 4.8e-55 186.6 0.0 7e-55 186.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 EEQ72036.1 - 9.5e-05 22.3 0.0 0.0004 20.3 0.0 2.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.17 EEQ72036.1 - 0.00019 21.0 0.0 0.00036 20.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_10 PF13673.1 EEQ72036.1 - 0.014 15.4 0.0 0.061 13.4 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEQ72036.1 - 0.051 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF399 PF04187.8 EEQ72037.1 - 0.1 12.0 0.0 3.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF399 adh_short PF00106.20 EEQ72037.1 - 0.72 9.7 3.1 6.2 6.7 0.0 2.3 1 1 1 2 2 2 0 short chain dehydrogenase Laminin_B PF00052.13 EEQ72038.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Laminin B (Domain IV) TFIIIC_delta PF12657.2 EEQ72039.1 - 0.023 14.4 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term NDT80_PhoG PF05224.7 EEQ72041.1 - 1e-37 129.9 0.2 3.8e-37 128.0 0.0 2.1 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Hexokinase_1 PF00349.16 EEQ72043.1 - 1.2e-36 125.9 0.0 1.8e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EEQ72043.1 - 9.2e-34 116.7 0.0 9e-27 93.8 0.0 2.5 2 0 0 2 2 2 2 Hexokinase p450 PF00067.17 EEQ72044.1 - 7.7e-60 202.7 0.0 1e-59 202.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TDH PF03347.8 EEQ72044.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Vibrio thermostable direct hemolysin DUF1389 PF07146.6 EEQ72045.1 - 0.027 13.5 0.0 0.04 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1389) COX14 PF14880.1 EEQ72047.1 - 2.4e-17 62.3 0.3 2.4e-17 62.3 0.2 2.3 3 0 0 3 3 3 1 Cytochrome oxidase c assembly DUF2458 PF10454.4 EEQ72048.1 - 1.1e-48 164.9 0.5 1.4e-48 164.6 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) Sec66 PF09802.4 EEQ72048.1 - 0.29 10.5 1.9 0.28 10.5 0.5 1.5 2 0 0 2 2 2 0 Preprotein translocase subunit Sec66 DAHP_synth_1 PF00793.15 EEQ72050.1 - 3.7e-94 314.4 0.0 4.6e-94 314.1 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Thiolase_N PF00108.18 EEQ72053.1 - 2.8e-77 259.2 0.1 4.5e-77 258.5 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EEQ72053.1 - 1.7e-46 156.6 0.4 1.7e-46 156.6 0.3 2.0 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EEQ72053.1 - 0.013 15.0 1.0 0.013 15.0 0.7 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Ribosomal_L50 PF10501.4 EEQ72054.1 - 1.5e-25 89.3 0.0 3.6e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 Ribosomal subunit 39S Rtf2 PF04641.7 EEQ72055.1 - 1e-60 205.1 0.3 1.3e-60 204.8 0.2 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EEQ72055.1 - 4.9e-09 35.5 0.3 0.0047 16.4 0.1 2.9 3 0 0 3 3 3 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EEQ72055.1 - 1.2e-06 28.1 0.5 3.9e-06 26.4 0.4 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EEQ72055.1 - 0.003 17.2 0.2 0.0068 16.1 0.1 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EEQ72055.1 - 0.0074 16.0 0.7 0.034 13.9 0.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEQ72055.1 - 0.036 13.7 0.5 0.096 12.3 0.3 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PRKCSH-like PF12999.2 EEQ72056.1 - 5.3e-47 159.6 7.6 1.2e-44 151.9 5.3 2.5 1 1 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EEQ72056.1 - 1.4e-29 102.5 3.3 2.2e-29 101.9 0.5 2.4 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EEQ72056.1 - 2.4e-11 44.2 1.0 7.6e-11 42.6 0.7 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.5 EEQ72056.1 - 0.0032 16.7 0.8 0.0062 15.8 0.5 1.4 1 0 0 1 1 1 1 Autophagy-related protein 27 HeH PF12949.2 EEQ72056.1 - 0.046 13.2 0.2 2.9 7.5 0.0 3.0 3 0 0 3 3 3 0 HeH/LEM domain DUF3348 PF11828.3 EEQ72056.1 - 1.9 7.8 7.7 1.1 8.6 3.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3348) GAS PF13851.1 EEQ72056.1 - 4.2 6.5 11.4 10 5.2 7.9 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TBPIP PF07106.8 EEQ72056.1 - 5.2 6.5 9.5 2 7.9 3.5 2.4 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ADIP PF11559.3 EEQ72056.1 - 6.6 6.6 10.6 1.5 8.7 4.5 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Macoilin PF09726.4 EEQ72056.1 - 9.3 4.3 11.1 1.6 6.9 5.3 1.4 2 0 0 2 2 2 0 Transmembrane protein PV-1 PF06637.6 EEQ72058.1 - 0.081 11.4 0.0 0.086 11.3 0.0 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) GFA PF04828.9 EEQ72060.1 - 4.1e-15 55.4 0.4 1.3e-10 41.0 0.0 2.5 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme RRN7 PF11781.3 EEQ72060.1 - 0.15 11.5 0.2 0.15 11.5 0.1 3.6 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 NmrA PF05368.8 EEQ72061.1 - 8.2e-43 146.3 0.0 1.1e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEQ72061.1 - 1.1e-17 64.6 0.0 1.5e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EEQ72061.1 - 2e-07 29.9 0.0 3.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EEQ72061.1 - 0.00014 21.3 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EEQ72061.1 - 0.017 15.0 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.20 EEQ72061.1 - 0.02 14.7 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 short chain dehydrogenase DXP_reductoisom PF02670.11 EEQ72061.1 - 0.051 14.1 0.0 0.14 12.7 0.0 1.7 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase PAP_assoc PF03828.14 EEQ72063.1 - 5e-13 48.7 0.1 1.1e-12 47.6 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EEQ72063.1 - 3.2e-08 33.7 0.0 3.7e-07 30.3 0.0 2.3 1 1 0 1 1 1 1 Nucleotidyltransferase domain FAP PF07174.6 EEQ72065.1 - 0.13 11.5 16.7 0.16 11.2 11.5 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) TPPII_N PF12583.3 EEQ72065.1 - 0.32 11.1 3.8 0.44 10.6 2.7 1.2 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Lamp PF01299.12 EEQ72065.1 - 0.42 9.7 2.7 0.6 9.1 1.9 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) DUF605 PF04652.11 EEQ72065.1 - 0.57 9.5 6.2 0.74 9.1 4.3 1.2 1 0 0 1 1 1 0 Vta1 like PLRV_ORF5 PF01690.12 EEQ72065.1 - 1.2 8.2 6.8 1.8 7.6 4.7 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DEC-1_N PF04625.8 EEQ72065.1 - 1.9 7.0 16.6 2.7 6.5 11.5 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region MGC-24 PF05283.6 EEQ72065.1 - 5.2 6.8 8.5 7.7 6.2 5.9 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Aldo_ket_red PF00248.16 EEQ72066.1 - 7.7e-72 241.4 0.0 1e-71 241.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Pam16 PF03656.8 EEQ72067.1 - 2.5e-35 121.0 0.7 2.9e-35 120.8 0.5 1.0 1 0 0 1 1 1 1 Pam16 DdrB PF12747.2 EEQ72067.1 - 0.075 12.7 0.3 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 DdrB-like protein DUF2841 PF11001.3 EEQ72068.1 - 2.5e-08 33.8 0.2 4.1e-08 33.1 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2841) Pex24p PF06398.6 EEQ72070.1 - 6.1e-98 327.9 0.0 7.6e-98 327.6 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3188 PF11384.3 EEQ72070.1 - 0.29 10.7 2.1 0.62 9.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) NAD_binding_10 PF13460.1 EEQ72071.1 - 7.5e-17 61.9 0.0 3.1e-16 59.9 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEQ72071.1 - 7e-07 28.9 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EEQ72071.1 - 0.0014 18.5 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase DUF3939 PF13075.1 EEQ72071.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3939) NmrA PF05368.8 EEQ72071.1 - 0.044 13.0 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 EEQ72071.1 - 0.076 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain MAP7 PF05672.6 EEQ72074.1 - 0.012 14.9 3.6 0.015 14.7 2.5 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family 5_3_exonuc_N PF02739.11 EEQ72074.1 - 0.091 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain DUF706 PF05153.10 EEQ72077.1 - 1.6e-124 414.2 1.7 2.2e-124 413.7 1.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 EEQ72077.1 - 0.026 14.5 0.2 0.51 10.3 0.1 2.5 1 1 0 1 1 1 0 HD domain Methyltransf_18 PF12847.2 EEQ72078.1 - 6.2e-07 29.9 0.0 8.3e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ72078.1 - 0.00021 21.6 0.0 0.00038 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ72078.1 - 0.00068 19.3 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ72078.1 - 0.007 16.8 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ72078.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain adh_short PF00106.20 EEQ72078.1 - 0.024 14.5 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Methyltransf_26 PF13659.1 EEQ72078.1 - 0.057 13.4 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ72078.1 - 0.097 13.0 0.0 0.16 12.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ72078.1 - 0.099 12.2 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EEQ72078.1 - 0.14 11.2 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Fungal_trans PF04082.13 EEQ72079.1 - 5.7e-24 84.3 0.1 8.5e-24 83.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAT PF02259.18 EEQ72081.1 - 1.5e-130 435.3 0.9 2.6e-130 434.5 0.1 1.8 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.3 EEQ72081.1 - 6.6e-64 214.6 1.6 1.7e-60 203.6 0.8 3.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 EEQ72081.1 - 2.4e-56 190.8 0.2 9.5e-56 188.8 0.4 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 EEQ72081.1 - 6.1e-40 135.3 1.1 5.1e-39 132.4 0.0 3.3 3 0 0 3 3 3 1 Rapamycin binding domain HEAT_2 PF13646.1 EEQ72081.1 - 7e-20 71.1 13.5 5.4e-05 23.3 0.0 8.4 7 2 3 10 10 10 6 HEAT repeats HEAT_EZ PF13513.1 EEQ72081.1 - 1.1e-16 60.7 12.9 7.4e-05 23.1 0.2 11.8 10 2 4 14 14 13 3 HEAT-like repeat FATC PF02260.15 EEQ72081.1 - 4.7e-15 54.7 0.3 1e-14 53.6 0.2 1.6 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 EEQ72081.1 - 9.9e-14 50.1 19.9 0.033 14.2 0.0 12.9 14 0 0 14 14 14 3 HEAT repeat Adaptin_N PF01602.15 EEQ72081.1 - 5.6e-08 31.5 2.8 0.087 11.1 0.0 5.4 3 2 0 3 3 3 2 Adaptin N terminal region UME PF08064.8 EEQ72081.1 - 0.00012 21.9 0.9 12 5.8 0.1 5.9 6 1 1 7 7 7 0 UME (NUC010) domain TPR_7 PF13176.1 EEQ72081.1 - 0.049 13.4 0.4 16 5.5 0.0 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ72081.1 - 0.18 12.1 5.1 13 6.1 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Mit_ribos_Mrp51 PF11709.3 EEQ72082.1 - 2e-103 345.9 0.0 2.4e-103 345.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Ribosomal_S17e PF00833.13 EEQ72083.1 - 2.9e-58 194.9 0.5 3.5e-58 194.6 0.4 1.1 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 EEQ72083.1 - 0.027 15.1 0.1 0.04 14.6 0.0 1.3 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal RPAP2_Rtr1 PF04181.8 EEQ72084.1 - 5.2e-18 64.9 0.0 9.2e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family Mito_fiss_reg PF05308.6 EEQ72084.1 - 0.52 9.6 8.0 0.89 8.8 5.6 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator SH3_2 PF07653.12 EEQ72085.1 - 3.4e-11 42.4 0.1 6.3e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEQ72085.1 - 1.3e-09 37.3 0.2 2.8e-09 36.2 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEQ72085.1 - 1.6e-09 37.2 0.2 3.6e-09 36.0 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain TFIIA PF03153.8 EEQ72085.1 - 0.0034 17.3 25.0 0.0034 17.3 17.3 3.2 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Aldedh PF00171.17 EEQ72085.1 - 0.15 10.3 1.5 0.23 9.7 1.0 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family MFS_1 PF07690.11 EEQ72086.1 - 5.2e-08 31.9 0.0 2.8e-05 22.9 0.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1077 PF06417.7 EEQ72087.1 - 1.8e-54 182.3 2.2 2.3e-54 182.0 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) CopD PF05425.8 EEQ72087.1 - 0.021 15.0 0.3 0.035 14.3 0.2 1.3 1 0 0 1 1 1 0 Copper resistance protein D Adaptin_N PF01602.15 EEQ72088.1 - 6.1e-129 430.7 5.6 7.4e-129 430.4 3.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EEQ72088.1 - 2.5e-19 69.8 1.6 4.3e-18 65.7 0.0 3.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EEQ72088.1 - 1.6e-15 57.1 2.6 1.8e-09 37.7 0.1 4.5 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EEQ72088.1 - 3.1e-11 42.3 5.1 0.0071 16.3 0.0 5.8 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 EEQ72088.1 - 5.6e-06 26.6 6.6 0.068 13.6 0.0 6.1 5 1 1 6 6 6 2 HEAT-like repeat Atx10homo_assoc PF09759.4 EEQ72088.1 - 3.3e-05 23.5 0.1 0.37 10.5 0.0 4.0 3 1 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 EEQ72088.1 - 0.00086 19.0 3.6 0.78 9.6 0.0 5.2 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Carbpep_Y_N PF05388.6 EEQ72088.1 - 0.068 13.3 0.1 16 5.6 0.0 2.7 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide AF0941-like PF14591.1 EEQ72088.1 - 0.11 12.6 0.5 0.28 11.2 0.4 1.7 1 0 0 1 1 1 0 AF0941-like Aminotran_5 PF00266.14 EEQ72089.1 - 7e-07 28.3 0.0 1.8e-06 26.9 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EEQ72089.1 - 0.0046 16.0 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Lactamase_B PF00753.22 EEQ72090.1 - 3.7e-05 23.4 0.0 0.0043 16.7 0.0 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EEQ72090.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain MFS_1 PF07690.11 EEQ72091.1 - 5.7e-31 107.5 23.0 5.7e-31 107.5 15.9 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EEQ72091.1 - 0.035 13.8 1.5 0.11 12.3 0.3 2.4 3 0 0 3 3 3 0 MFS_1 like family Hemerythrin PF01814.18 EEQ72093.1 - 5.2e-10 39.5 5.0 6.3e-10 39.3 2.9 1.6 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain DUF2422 PF10337.4 EEQ72093.1 - 0.22 10.2 0.6 0.23 10.1 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Fe-S_biosyn PF01521.15 EEQ72094.1 - 3.7e-09 36.5 0.0 0.0034 17.3 0.0 2.2 2 0 0 2 2 2 2 Iron-sulphur cluster biosynthesis FAD_binding_4 PF01565.18 EEQ72096.1 - 7.6e-18 64.3 0.2 1.2e-17 63.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.9 EEQ72096.1 - 3.7e-10 39.8 1.9 3.1e-06 26.9 0.1 2.4 2 1 0 2 2 2 2 D-arabinono-1,4-lactone oxidase Paf67 PF10255.4 EEQ72097.1 - 2.5e-155 517.3 0.0 3e-155 517.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EEQ72097.1 - 0.017 14.9 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat RRM_6 PF14259.1 EEQ72098.1 - 0.00091 19.1 0.0 0.28 11.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF433 PF04255.9 EEQ72098.1 - 0.084 12.2 0.0 0.38 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF433) Cytochrom_B561 PF03188.11 EEQ72100.1 - 0.001 18.8 9.5 0.0031 17.3 6.6 1.8 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.12 EEQ72100.1 - 0.0068 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 DOMON domain PARP PF00644.15 EEQ72100.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain SdpI PF13630.1 EEQ72100.1 - 3.7 7.3 9.3 0.21 11.3 1.0 2.5 2 0 0 2 2 2 0 SdpI/YhfL protein family Acetyltransf_1 PF00583.19 EEQ72101.1 - 0.00068 19.6 0.5 0.0029 17.5 0.1 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ72101.1 - 0.00073 19.6 0.0 0.0021 18.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEQ72101.1 - 0.0013 18.5 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ72101.1 - 0.02 14.6 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein PDH PF02153.12 EEQ72102.1 - 2.1e-10 39.9 0.0 3.1e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 EEQ72102.1 - 7.9e-07 29.0 0.0 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EEQ72102.1 - 5e-06 26.8 0.0 9.7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EEQ72102.1 - 4.1e-05 23.0 0.0 6.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EEQ72102.1 - 0.00034 19.8 0.0 0.00053 19.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EEQ72102.1 - 0.0016 18.1 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 EEQ72102.1 - 0.054 13.7 0.0 0.099 12.9 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_Gly3P_dh_N PF01210.18 EEQ72102.1 - 0.072 12.8 0.0 0.24 11.1 0.0 1.8 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IlvN PF07991.7 EEQ72102.1 - 0.074 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Rossmann-like PF10727.4 EEQ72102.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain Ribosomal_S11 PF00411.14 EEQ72103.1 - 1e-40 138.3 0.4 1.2e-40 138.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 AAR2 PF05282.6 EEQ72104.1 - 1.9e-94 316.5 0.0 2.4e-94 316.2 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein Ribosomal_S9 PF00380.14 EEQ72105.1 - 8.1e-40 135.8 0.5 9.2e-40 135.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13 PF00572.13 EEQ72106.1 - 1.6e-39 134.8 0.0 2e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Uricase PF01014.13 EEQ72107.1 - 1.5e-85 284.2 2.6 1.6e-47 161.0 0.5 2.0 2 0 0 2 2 2 2 Uricase RICTOR_N PF14664.1 EEQ72108.1 - 8.6e-142 472.1 0.2 6e-141 469.3 0.1 2.1 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EEQ72108.1 - 4.7e-90 300.5 0.9 3.8e-88 294.2 0.1 3.8 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EEQ72108.1 - 9e-45 151.3 0.1 1.5e-43 147.3 0.0 2.8 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EEQ72108.1 - 4.7e-24 84.1 4.7 1.8e-23 82.2 0.1 4.0 6 0 0 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 EEQ72108.1 - 9.5e-12 44.4 10.9 2.1e-11 43.3 7.5 1.6 1 0 0 1 1 1 1 Hr1 repeat Arm PF00514.18 EEQ72108.1 - 2.4 8.1 7.5 12 5.9 0.1 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Paf1 PF03985.8 EEQ72110.1 - 5.9e-38 130.7 0.1 1.3e-26 93.3 0.0 3.0 2 1 0 2 2 2 2 Paf1 Actin PF00022.14 EEQ72111.1 - 3.8e-31 107.8 0.0 4.8e-17 61.4 0.0 2.8 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EEQ72111.1 - 0.0013 17.4 0.0 0.15 10.6 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Arf PF00025.16 EEQ72112.1 - 1.6e-74 248.8 0.0 1.9e-74 248.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EEQ72112.1 - 1.2e-11 44.1 0.0 1.6e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EEQ72112.1 - 8.3e-11 41.5 0.0 9.8e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EEQ72112.1 - 2.1e-10 39.8 0.8 1.1e-06 27.5 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EEQ72112.1 - 8.5e-09 34.8 0.0 1.1e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EEQ72112.1 - 3.8e-08 33.8 0.0 5.3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEQ72112.1 - 3.9e-06 26.7 0.0 5.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEQ72112.1 - 1.2e-05 24.8 0.0 0.0017 17.8 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EEQ72112.1 - 0.0062 15.8 0.4 0.032 13.5 0.3 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF3986 PF13143.1 EEQ72112.1 - 0.11 12.9 0.2 0.26 11.7 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) Sugar_tr PF00083.19 EEQ72113.1 - 3.1e-73 246.9 26.4 1.3e-48 165.7 8.9 3.1 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EEQ72113.1 - 4.2e-10 38.8 41.8 5.8e-07 28.5 6.6 3.6 2 2 0 2 2 2 2 Major Facilitator Superfamily Catalase PF00199.14 EEQ72114.1 - 1.2e-186 619.9 0.2 1.6e-186 619.5 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EEQ72114.1 - 1.3e-10 40.9 0.6 3.5e-10 39.6 0.0 2.0 2 0 0 2 2 2 1 Catalase-related immune-responsive Ribosomal_60s PF00428.14 EEQ72116.1 - 0.077 13.4 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Atrophin-1 PF03154.10 EEQ72116.1 - 0.32 9.0 3.0 0.39 8.8 2.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF3936 PF13072.1 EEQ72117.1 - 0.05 13.0 0.0 4 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3936) Ycf54 PF10674.4 EEQ72117.1 - 0.12 12.5 0.3 0.54 10.4 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2488) DEAD PF00270.24 EEQ72118.1 - 5e-19 68.4 0.0 8.7e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EEQ72118.1 - 2.4e-07 30.7 0.0 1.5e-06 28.2 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EEQ72118.1 - 3.8e-06 26.6 0.1 7.9e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 EEQ72118.1 - 0.066 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Zn_clus PF00172.13 EEQ72119.1 - 7.5e-06 25.7 3.9 1.5e-05 24.7 2.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEQ72119.1 - 4.8e-05 22.1 0.3 8.5e-05 21.3 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Rer1 PF03248.8 EEQ72121.1 - 3.2e-81 271.1 2.8 3.6e-81 270.9 2.0 1.0 1 0 0 1 1 1 1 Rer1 family ECH PF00378.15 EEQ72122.1 - 1.7e-70 236.9 0.0 2e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EEQ72122.1 - 0.027 14.2 0.7 0.19 11.5 0.1 2.1 2 0 0 2 2 2 0 Peptidase family S49 ECH_C PF13766.1 EEQ72122.1 - 0.088 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region A_deaminase PF00962.17 EEQ72124.1 - 1.6e-41 142.3 0.0 3.1e-41 141.4 0.0 1.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase Mur_ligase_M PF08245.7 EEQ72125.1 - 7.8e-08 32.5 0.0 2.2e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EEQ72125.1 - 8.9e-05 22.4 0.0 0.00019 21.3 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Acetyltransf_1 PF00583.19 EEQ72126.1 - 0.065 13.2 0.1 0.14 12.1 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ72126.1 - 0.078 13.1 0.1 0.3 11.2 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Methyltransf_2 PF00891.13 EEQ72127.1 - 1.3e-35 122.7 0.0 1.9e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EEQ72127.1 - 0.00026 21.5 0.0 0.00084 19.8 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ72127.1 - 0.0014 18.3 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF3419 PF11899.3 EEQ72129.1 - 2.9e-150 500.2 0.0 3.9e-150 499.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_26 PF13659.1 EEQ72129.1 - 0.0076 16.2 0.0 0.054 13.5 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ72129.1 - 0.16 11.5 0.0 0.88 9.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Lipase_3 PF01764.20 EEQ72131.1 - 0.0001 21.9 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EEQ72131.1 - 0.0043 16.8 0.0 0.0073 16.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 EEQ72131.1 - 0.091 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) VPS9 PF02204.13 EEQ72132.1 - 1.5e-24 85.9 0.1 3.9e-24 84.6 0.0 1.7 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain ECM11 PF15463.1 EEQ72133.1 - 5.5e-42 143.3 0.7 1e-41 142.5 0.0 1.8 2 0 0 2 2 2 1 Extracellular mutant protein 11 RNA_pol_I_TF PF04090.7 EEQ72134.1 - 7.9e-10 38.3 0.0 1.8e-05 24.1 0.0 2.4 2 1 0 2 2 2 2 RNA polymerase I specific initiation factor zf-RING_2 PF13639.1 EEQ72135.1 - 9.1e-15 54.2 5.6 1.5e-14 53.5 3.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EEQ72135.1 - 4.9e-09 36.1 2.0 8.6e-09 35.3 1.4 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EEQ72135.1 - 1.9e-07 30.9 4.5 3e-07 30.3 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ72135.1 - 5.8e-07 29.0 5.0 9.3e-07 28.4 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ72135.1 - 9.7e-07 28.4 3.2 1.5e-06 27.8 2.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EEQ72135.1 - 0.00016 21.2 2.2 0.00025 20.6 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEQ72135.1 - 0.00035 20.3 2.3 0.00093 18.9 1.6 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EEQ72135.1 - 0.0018 18.2 6.6 0.003 17.5 4.6 1.4 1 0 0 1 1 1 1 RING-variant domain zf-Nse PF11789.3 EEQ72135.1 - 0.007 15.8 1.6 0.015 14.7 1.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 EEQ72135.1 - 0.011 15.6 3.7 0.021 14.7 2.5 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EEQ72135.1 - 0.027 14.1 2.2 0.068 12.8 1.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_1 PF14446.1 EEQ72135.1 - 0.15 11.8 4.9 0.33 10.7 3.4 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 EEQ72135.1 - 0.48 10.4 2.7 0.88 9.6 1.9 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 EEQ72135.1 - 0.51 9.9 3.9 0.82 9.3 2.7 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain APH PF01636.18 EEQ72136.1 - 7.3e-06 25.8 0.5 4.8e-05 23.2 0.2 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Fungal_trans_2 PF11951.3 EEQ72139.1 - 1.3e-08 33.8 0.9 2.4e-08 32.9 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DEAD PF00270.24 EEQ72140.1 - 1.2e-24 86.6 0.0 1.9e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ72140.1 - 5.8e-11 42.1 0.1 2.1e-10 40.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 EEQ72140.1 - 8.7e-10 39.0 0.1 7.3e-09 36.0 0.1 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF1998) ResIII PF04851.10 EEQ72140.1 - 0.0019 18.0 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_S4e PF00900.15 EEQ72140.1 - 0.068 12.8 0.1 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 Ribosomal family S4e Ran_BP1 PF00638.13 EEQ72141.1 - 7.4e-15 55.0 0.5 2.3e-07 30.9 0.1 2.6 2 0 0 2 2 2 2 RanBP1 domain Yip1 PF04893.12 EEQ72142.1 - 4.6e-13 49.0 17.4 8.1e-13 48.2 12.1 1.4 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 EEQ72142.1 - 0.12 11.9 7.7 0.19 11.4 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) IBR PF01485.16 EEQ72143.1 - 4.7e-06 26.3 3.1 4.7e-06 26.3 2.1 4.3 4 1 0 4 4 4 3 IBR domain adh_short PF00106.20 EEQ72144.1 - 2.8e-59 199.7 9.0 1.6e-30 106.2 0.6 2.6 3 0 0 3 3 3 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 EEQ72144.1 - 1.2e-30 105.4 0.0 2.5e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 EEQ72144.1 - 7e-27 94.2 1.4 1.4e-13 50.8 0.1 2.4 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.14 EEQ72144.1 - 0.00015 20.8 0.4 0.014 14.4 0.1 2.4 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4170 PF13773.1 EEQ72144.1 - 0.17 11.8 0.4 0.54 10.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4170) DUF543 PF04418.7 EEQ72144.1 - 2.1 8.3 5.3 14 5.7 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF543) 3HCDH_N PF02737.13 EEQ72144.1 - 3.8 7.1 5.8 15 5.1 0.2 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KAP_NTPase PF07693.9 EEQ72145.1 - 0.014 14.3 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain UPF0079 PF02367.12 EEQ72145.1 - 0.034 13.7 0.0 0.075 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 GFA PF04828.9 EEQ72146.1 - 6.3e-18 64.5 0.4 8.9e-18 64.0 0.3 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme LysM PF01476.15 EEQ72148.1 - 0.12 12.2 0.0 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 LysM domain Fungal_trans PF04082.13 EEQ72149.1 - 7.1e-34 116.8 1.1 2.1e-33 115.3 0.0 2.3 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ72149.1 - 0.019 14.8 3.9 0.034 14.0 2.7 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PigN PF04987.9 EEQ72151.1 - 1.4e-152 508.4 39.0 4.2e-97 325.5 10.8 3.2 2 1 1 3 3 3 3 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EEQ72151.1 - 1.1e-09 38.1 0.2 3.9e-08 33.0 0.0 2.1 1 1 1 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EEQ72151.1 - 1.5e-07 30.9 0.0 2.5e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EEQ72151.1 - 0.004 16.5 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF4363 PF14276.1 EEQ72151.1 - 0.072 12.8 0.1 0.29 10.8 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Csm1 PF12539.3 EEQ72152.1 - 1.2e-27 96.2 0.1 3.9e-27 94.5 0.0 2.0 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 Med4 PF10018.4 EEQ72152.1 - 0.0036 16.7 2.5 0.0036 16.7 1.7 2.8 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Reo_sigmaC PF04582.7 EEQ72152.1 - 0.34 10.0 5.7 0.61 9.2 1.6 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 EEQ72152.1 - 0.35 11.0 8.0 1.3 9.1 4.9 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 EEQ72152.1 - 1.6 8.5 5.6 1.6 8.5 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Atg14 PF10186.4 EEQ72152.1 - 3.6 6.4 15.3 0.0096 14.9 3.9 1.5 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 AAA PF00004.24 EEQ72153.1 - 1e-37 129.3 0.0 3.1e-37 127.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EEQ72153.1 - 8.9e-06 25.6 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEQ72153.1 - 2.1e-05 24.2 0.1 0.00023 20.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EEQ72153.1 - 2.1e-05 25.3 0.1 9.3e-05 23.2 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EEQ72153.1 - 2.7e-05 24.3 0.1 0.00065 19.8 0.1 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEQ72153.1 - 3.6e-05 22.9 0.0 5.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EEQ72153.1 - 4.9e-05 23.3 1.3 0.00065 19.7 0.0 2.4 2 1 1 3 3 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EEQ72153.1 - 0.0001 21.7 0.0 0.00051 19.5 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 EEQ72153.1 - 0.00017 21.5 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EEQ72153.1 - 0.0004 20.2 0.0 0.0008 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EEQ72153.1 - 0.00044 19.7 0.2 0.04 13.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EEQ72153.1 - 0.0009 18.4 0.1 0.0017 17.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EEQ72153.1 - 0.00097 19.2 0.0 0.0033 17.4 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.17 EEQ72153.1 - 0.0013 18.8 0.0 0.0044 17.1 0.0 2.0 2 1 0 2 2 1 1 RNA helicase NACHT PF05729.7 EEQ72153.1 - 0.0035 17.0 0.0 0.011 15.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 EEQ72153.1 - 0.0037 16.9 0.1 0.027 14.2 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 EEQ72153.1 - 0.004 17.1 0.0 0.0076 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEQ72153.1 - 0.0042 16.1 0.0 0.0075 15.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_24 PF13479.1 EEQ72153.1 - 0.0069 15.9 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEQ72153.1 - 0.0079 16.5 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.12 EEQ72153.1 - 0.0095 14.8 0.0 0.023 13.5 0.0 1.6 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 EEQ72153.1 - 0.018 14.5 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 EEQ72153.1 - 0.022 15.0 0.0 0.067 13.4 0.0 2.0 1 1 0 1 1 1 0 ABC transporter SKI PF01202.17 EEQ72153.1 - 0.025 14.4 1.2 0.26 11.1 0.0 2.6 3 0 0 3 3 2 0 Shikimate kinase CPT PF07931.7 EEQ72153.1 - 0.028 14.0 0.0 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_11 PF13086.1 EEQ72153.1 - 0.055 13.0 0.1 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EEQ72153.1 - 0.056 12.3 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Rad17 PF03215.10 EEQ72153.1 - 0.065 11.9 0.0 0.096 11.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 EEQ72153.1 - 0.084 12.5 0.0 0.26 10.9 0.0 1.7 1 1 1 2 2 2 0 Archaeal ATPase NB-ARC PF00931.17 EEQ72153.1 - 0.11 11.2 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain UPF0079 PF02367.12 EEQ72153.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 EEQ72153.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Cys_Met_Meta_PP PF01053.15 EEQ72154.1 - 3.8e-140 466.5 0.0 4.4e-140 466.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EEQ72154.1 - 3.8e-05 22.6 0.0 6.6e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EEQ72154.1 - 5.2e-05 22.4 0.0 0.00018 20.6 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EEQ72154.1 - 6.1e-05 22.1 0.0 8.7e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EEQ72154.1 - 0.00077 18.6 0.0 0.0022 17.2 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase POTRA_2 PF08479.6 EEQ72154.1 - 0.041 13.5 0.0 0.15 11.7 0.0 1.9 1 0 0 1 1 1 0 POTRA domain, ShlB-type MTP18 PF10558.4 EEQ72157.1 - 1.9e-67 225.7 0.1 2.9e-67 225.1 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DUF2964 PF11177.3 EEQ72157.1 - 0.015 15.2 0.3 0.027 14.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) DUF2611 PF11022.3 EEQ72158.1 - 9.8e-27 92.8 0.2 1e-26 92.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) AAT PF03417.11 EEQ72159.1 - 4.9e-29 101.3 0.0 5.9e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 EEQ72159.1 - 6e-05 23.3 0.0 0.00014 22.1 0.0 1.6 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase ACPS PF01648.15 EEQ72160.1 - 1.1e-15 57.4 0.0 1.5e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily BcsB PF03170.8 EEQ72160.1 - 0.13 10.2 0.0 0.15 10.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit PHP PF02811.14 EEQ72162.1 - 3.4e-09 36.7 0.0 8e-09 35.5 0.0 1.6 1 1 0 1 1 1 1 PHP domain FKBP_C PF00254.23 EEQ72164.1 - 0.00045 20.1 0.0 0.00054 19.9 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MBA1 PF07961.6 EEQ72164.1 - 0.083 11.7 0.0 0.098 11.4 0.0 1.1 1 0 0 1 1 1 0 MBA1-like protein CTNNB1_binding PF08347.6 EEQ72166.1 - 0.44 10.7 6.9 0.61 10.3 4.8 1.2 1 0 0 1 1 1 0 N-terminal CTNNB1 binding FAM104 PF15434.1 EEQ72167.1 - 0.91 9.7 5.4 0.16 12.2 1.1 1.6 2 0 0 2 2 2 0 Family 104 APH PF01636.18 EEQ72169.1 - 1.9e-09 37.6 0.2 4.8e-08 33.0 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EEQ72169.1 - 0.02 14.0 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Pex14_N PF04695.8 EEQ72170.1 - 0.00083 19.4 0.4 0.00083 19.4 0.2 3.9 5 0 0 5 5 5 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Herpes_gE PF02480.11 EEQ72170.1 - 0.031 12.5 0.0 0.061 11.5 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Baculo_PEP_C PF04513.7 EEQ72170.1 - 0.032 14.0 0.9 0.059 13.1 0.7 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4404 PF14357.1 EEQ72170.1 - 0.15 12.4 4.3 0.096 13.1 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) EAP30 PF04157.11 EEQ72171.1 - 1.5e-51 174.7 0.0 2.1e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EEQ72171.1 - 4.7e-30 103.2 0.0 8.3e-30 102.4 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-Sec23_Sec24 PF04810.10 EEQ72171.1 - 7.6e-05 22.1 3.1 0.0036 16.8 0.1 2.6 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger zf-RanBP PF00641.13 EEQ72171.1 - 0.00022 20.2 12.9 0.0022 17.0 0.8 2.7 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others GRAM PF02893.15 EEQ72171.1 - 0.0078 15.7 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 GRAM domain DZR PF12773.2 EEQ72171.1 - 0.085 12.6 6.0 0.054 13.3 0.5 2.5 3 0 0 3 3 3 0 Double zinc ribbon GCC2_GCC3 PF07699.8 EEQ72171.1 - 0.53 9.9 3.1 3.3 7.3 0.3 2.5 2 1 0 2 2 2 0 GCC2 and GCC3 Rubredoxin PF00301.15 EEQ72171.1 - 7.4 6.5 6.8 5.1 7.0 0.1 3.6 4 1 1 5 5 5 0 Rubredoxin SAC3_GANP PF03399.11 EEQ72172.1 - 3e-70 235.9 0.3 5.1e-70 235.1 0.2 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EEQ72172.1 - 1.8e-06 27.8 0.1 5.9e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 Myco_arth_vir_N PF09610.5 EEQ72172.1 - 0.046 13.6 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) NUDE_C PF04880.8 EEQ72174.1 - 0.055 13.8 0.9 0.064 13.6 0.7 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region MSP1_C PF07462.6 EEQ72174.1 - 0.16 10.3 0.4 0.18 10.1 0.3 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus SH3_1 PF00018.23 EEQ72176.1 - 3.8e-22 77.3 0.0 3.2e-11 42.4 0.0 3.4 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.1 EEQ72176.1 - 2.3e-14 52.7 0.0 4.7e-06 26.0 0.0 2.9 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 EEQ72176.1 - 1.8e-13 50.2 0.0 3.6e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 EEQ72176.1 - 1.5e-09 37.1 0.0 4.4e-05 22.8 0.0 2.9 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 EEQ72176.1 - 1.2e-08 34.4 0.2 2.4e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 PB1 domain AFG1_ATPase PF03969.11 EEQ72177.1 - 5.7e-93 311.6 0.0 8.3e-88 294.6 0.0 2.3 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EEQ72177.1 - 2.2e-05 24.5 0.4 0.035 14.0 0.0 3.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EEQ72177.1 - 0.00098 19.0 0.0 0.0025 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEQ72177.1 - 0.0055 16.8 0.0 0.035 14.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EEQ72177.1 - 0.0089 16.2 0.1 0.026 14.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEQ72177.1 - 0.012 15.2 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EEQ72177.1 - 0.042 14.0 0.0 0.52 10.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Bac_DnaA PF00308.13 EEQ72177.1 - 0.043 13.4 0.1 0.54 9.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein NACHT PF05729.7 EEQ72177.1 - 0.066 12.8 0.0 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 NACHT domain DUF4124 PF13511.1 EEQ72178.1 - 0.51 10.4 2.4 0.76 9.8 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) Chitin_synth_1 PF01644.12 EEQ72179.1 - 2.5e-84 281.0 0.1 3.5e-84 280.5 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EEQ72179.1 - 9.3e-33 111.7 0.3 2e-32 110.6 0.2 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EEQ72179.1 - 1.8e-21 76.1 0.1 2.1e-20 72.6 0.0 2.3 1 1 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EEQ72179.1 - 2.3e-07 30.7 0.1 5.9e-07 29.3 0.1 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EEQ72179.1 - 4.6e-05 23.3 0.0 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF1361 PF07099.6 EEQ72179.1 - 0.011 15.5 2.4 0.028 14.2 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1361) TcpQ PF10671.4 EEQ72179.1 - 0.065 13.1 0.4 0.19 11.6 0.1 1.8 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q zf-DHHC PF01529.15 EEQ72179.1 - 3.6 6.9 5.8 9.1 5.6 4.0 1.6 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF1774 PF08611.5 EEQ72180.1 - 8.5e-38 128.4 1.5 8.5e-38 128.4 1.1 1.9 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1774) MIG-14_Wnt-bd PF06664.7 EEQ72180.1 - 0.13 11.0 10.8 0.017 13.9 2.4 2.3 2 1 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Peptidase_M28 PF04389.12 EEQ72181.1 - 1.5e-26 93.2 0.1 2.4e-26 92.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EEQ72181.1 - 8e-05 22.2 0.1 0.00015 21.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EEQ72181.1 - 0.014 14.2 0.1 1.1 7.9 0.0 2.2 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase R3H-assoc PF13902.1 EEQ72182.1 - 2.7e-24 85.5 5.7 2.7e-24 85.5 4.0 2.3 3 0 0 3 3 3 1 R3H-associated N-terminal domain R3H PF01424.17 EEQ72182.1 - 0.005 16.5 0.1 0.018 14.7 0.0 2.0 2 0 0 2 2 2 1 R3H domain DUF3328 PF11807.3 EEQ72183.1 - 7e-41 140.2 0.8 9.1e-41 139.9 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Hist_deacetyl PF00850.14 EEQ72186.1 - 1.6e-58 198.4 0.0 3.1e-58 197.5 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylase domain Gly_acyl_tr_N PF06021.6 EEQ72188.1 - 0.036 13.4 2.0 0.042 13.2 0.6 1.6 1 1 1 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase FPL PF09758.4 EEQ72188.1 - 0.2 11.4 3.6 0.17 11.6 1.1 1.9 1 1 1 2 2 2 0 Uncharacterised conserved protein Pkinase PF00069.20 EEQ72189.1 - 8.9e-45 152.8 0.0 7.6e-44 149.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ72189.1 - 1.1e-25 90.2 0.0 2.7e-25 88.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ72189.1 - 0.0016 17.4 0.0 0.06 12.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like FHA PF00498.21 EEQ72189.1 - 0.0031 17.5 0.0 0.007 16.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain Pox_ser-thr_kin PF05445.6 EEQ72189.1 - 0.034 12.9 0.0 0.054 12.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-AN1 PF01428.11 EEQ72190.1 - 6.6e-24 83.5 26.6 2e-12 46.7 6.7 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 EEQ72190.1 - 0.017 15.0 4.6 0.017 15.0 3.2 3.0 2 1 0 2 2 2 0 IBR domain Transp_Tc5_C PF04236.10 EEQ72190.1 - 0.12 12.6 19.7 0.51 10.5 4.3 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Thymidylat_synt PF00303.14 EEQ72191.1 - 1.2e-110 368.8 0.0 1.3e-110 368.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase TGT PF01702.13 EEQ72192.1 - 3.4e-94 314.6 0.0 4.5e-94 314.2 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase MFS_1 PF07690.11 EEQ72193.1 - 4e-06 25.7 2.4 6.1e-06 25.1 1.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ72193.1 - 0.019 13.5 0.2 0.027 13.0 0.2 1.2 1 0 0 1 1 1 0 Sugar (and other) transporter DUF4339 PF14237.1 EEQ72193.1 - 0.039 13.5 0.0 0.081 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) PA_decarbox PF05870.6 EEQ72193.1 - 0.14 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) DUF1049 PF06305.6 EEQ72193.1 - 0.17 11.3 0.3 0.36 10.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Abhydrolase_6 PF12697.2 EEQ72194.1 - 8.5e-11 42.1 1.4 3.2e-06 27.2 0.2 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Ribosomal_L13e PF01294.13 EEQ72194.1 - 0.0017 17.8 0.0 0.003 17.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13e HsbA PF12296.3 EEQ72198.1 - 5e-26 90.9 5.8 5e-26 90.9 4.1 1.6 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Trypan_PARP PF05887.6 EEQ72198.1 - 1.8e-05 24.5 16.3 2.9e-05 23.9 11.3 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) PT PF04886.7 EEQ72198.1 - 0.00026 20.2 53.7 86 2.5 37.2 3.6 1 1 0 1 1 1 0 PT repeat DUF1664 PF07889.7 EEQ72198.1 - 0.037 13.8 0.1 6.5 6.5 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) WD40 PF00400.27 EEQ72199.1 - 4.5e-09 35.8 7.7 0.45 10.4 0.0 7.7 10 0 0 10 10 10 4 WD domain, G-beta repeat PQQ_2 PF13360.1 EEQ72199.1 - 1e-06 28.3 0.3 8.7e-05 22.0 0.1 3.3 3 1 0 3 3 3 1 PQQ-like domain Jacalin PF01419.12 EEQ72200.1 - 0.0013 18.5 0.0 0.0091 15.8 0.0 2.0 2 0 0 2 2 2 1 Jacalin-like lectin domain F-box PF00646.28 EEQ72200.1 - 0.002 17.7 1.1 0.0064 16.1 0.7 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EEQ72200.1 - 0.0059 16.3 1.9 0.16 11.7 0.7 2.7 3 0 0 3 3 3 1 F-box-like Rad4 PF03835.10 EEQ72202.1 - 1.1e-16 60.5 6.5 2.3e-16 59.5 4.5 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EEQ72202.1 - 9.4e-12 45.1 2.2 2.2e-11 43.9 1.5 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily CDC45 PF02724.9 EEQ72203.1 - 0.00018 19.7 13.7 0.00018 19.6 9.5 1.0 1 0 0 1 1 1 1 CDC45-like protein Sporozoite_P67 PF05642.6 EEQ72203.1 - 0.017 13.0 4.9 0.016 13.0 3.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen VID27 PF08553.5 EEQ72203.1 - 0.019 13.2 12.0 0.02 13.1 8.3 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein NurA PF09376.5 EEQ72203.1 - 0.046 13.2 0.9 0.055 12.9 0.6 1.1 1 0 0 1 1 1 0 NurA domain Vfa1 PF08432.5 EEQ72203.1 - 0.051 13.5 11.7 0.056 13.4 8.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RNase_H2_suC PF08615.6 EEQ72203.1 - 0.057 13.2 1.5 0.067 13.0 1.0 1.3 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CENP-T PF15511.1 EEQ72203.1 - 0.065 12.4 11.0 0.065 12.4 7.6 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T RRN3 PF05327.6 EEQ72203.1 - 0.067 11.2 9.5 0.064 11.3 6.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NPR3 PF03666.8 EEQ72203.1 - 0.067 11.7 2.3 0.065 11.7 1.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DDRGK PF09756.4 EEQ72203.1 - 0.13 11.6 15.7 0.14 11.5 10.9 1.1 1 0 0 1 1 1 0 DDRGK domain SAPS PF04499.10 EEQ72203.1 - 0.14 10.8 4.9 0.13 10.8 3.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Raftlin PF15250.1 EEQ72203.1 - 0.16 10.4 3.2 0.2 10.1 2.2 1.2 1 0 0 1 1 1 0 Raftlin DUF506 PF04720.7 EEQ72203.1 - 0.18 11.4 5.7 0.21 11.1 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF506) DUF4637 PF15470.1 EEQ72203.1 - 0.22 11.1 12.7 0.23 11.0 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Tom37_C PF11801.3 EEQ72203.1 - 0.25 11.2 3.2 0.29 10.9 2.2 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF3530 PF12048.3 EEQ72203.1 - 0.33 9.9 4.5 0.39 9.6 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) TRAP_alpha PF03896.11 EEQ72203.1 - 0.36 9.7 13.2 0.39 9.6 9.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit IFT57 PF10498.4 EEQ72203.1 - 0.45 9.2 10.0 0.49 9.0 6.9 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Sigma70_ner PF04546.8 EEQ72203.1 - 0.45 10.1 19.4 0.67 9.5 13.4 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Atg14 PF10186.4 EEQ72203.1 - 0.73 8.7 3.9 0.78 8.6 2.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Nop14 PF04147.7 EEQ72203.1 - 0.84 7.4 29.2 1 7.2 20.2 1.0 1 0 0 1 1 1 0 Nop14-like family Ycf1 PF05758.7 EEQ72203.1 - 1 7.0 8.1 0.93 7.1 5.6 1.0 1 0 0 1 1 1 0 Ycf1 HSP90 PF00183.13 EEQ72203.1 - 1 7.6 17.3 1 7.6 12.0 1.1 1 0 0 1 1 1 0 Hsp90 protein ECIST_Cterm PF14784.1 EEQ72203.1 - 1.3 9.0 4.3 1.8 8.5 3.0 1.2 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein RP-C_C PF11800.3 EEQ72203.1 - 1.3 8.6 5.9 1.6 8.4 4.1 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Sec62 PF03839.11 EEQ72203.1 - 1.5 8.1 4.8 1.6 8.1 3.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Cwf_Cwc_15 PF04889.7 EEQ72203.1 - 1.5 8.4 23.5 1.7 8.2 16.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Zip PF02535.17 EEQ72203.1 - 1.8 7.4 4.2 5.2 5.9 2.1 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter RR_TM4-6 PF06459.7 EEQ72203.1 - 3.6 7.4 11.8 3.9 7.2 8.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pilt PF15453.1 EEQ72203.1 - 4.5 6.8 9.0 5.2 6.6 6.2 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Nop53 PF07767.6 EEQ72203.1 - 4.8 6.0 19.0 5.6 5.8 13.2 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) YL1 PF05764.8 EEQ72203.1 - 4.9 6.6 24.6 5.8 6.4 17.0 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Cnd2 PF05786.9 EEQ72203.1 - 5.1 5.4 13.8 6.1 5.2 9.6 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 DUF2722 PF10846.3 EEQ72203.1 - 6.5 5.6 13.2 7.6 5.4 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spore_coat_CotO PF14153.1 EEQ72203.1 - 7 6.0 14.6 8.1 5.8 10.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Pox_Ag35 PF03286.9 EEQ72203.1 - 8.5 5.8 16.6 11 5.5 11.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein ADH_zinc_N_2 PF13602.1 EEQ72204.1 - 2.9e-05 24.9 0.5 0.00018 22.4 0.0 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EEQ72204.1 - 3.7e-05 23.2 0.1 0.00011 21.7 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase GMC_oxred_N PF00732.14 EEQ72205.1 - 1.7e-58 198.1 0.0 2.2e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EEQ72205.1 - 1.3e-34 119.5 0.0 5.4e-34 117.5 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EEQ72205.1 - 4.9e-06 25.6 0.2 0.036 12.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 EEQ72205.1 - 6.7e-05 23.0 0.9 0.34 10.9 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEQ72205.1 - 0.00012 22.0 0.0 0.00035 20.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEQ72205.1 - 0.00029 19.8 0.5 0.0023 16.8 0.1 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase TrkA_N PF02254.13 EEQ72205.1 - 0.0051 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Lycopene_cycl PF05834.7 EEQ72205.1 - 0.065 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein VacA2 PF03077.9 EEQ72205.1 - 0.27 10.8 2.6 5.9 6.5 0.3 2.6 2 0 0 2 2 2 0 Putative vacuolating cytotoxin Saccharop_dh PF03435.13 EEQ72206.1 - 5.4e-113 377.8 0.0 5.9e-112 374.4 0.0 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EEQ72206.1 - 6e-07 29.6 0.2 1.1e-06 28.8 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 EEQ72206.1 - 1.2e-06 28.6 0.3 2e-06 27.9 0.2 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EEQ72206.1 - 0.00052 20.2 0.1 0.00099 19.3 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.13 EEQ72206.1 - 0.0063 16.4 0.4 0.011 15.7 0.3 1.4 1 0 0 1 1 1 1 TrkA-N domain Semialdhyde_dh PF01118.19 EEQ72206.1 - 0.012 15.9 0.2 0.027 14.7 0.2 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain IlvN PF07991.7 EEQ72206.1 - 0.025 13.9 0.2 0.05 12.9 0.0 1.6 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF2325 PF10087.4 EEQ72206.1 - 0.043 13.6 0.1 0.082 12.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) 3Beta_HSD PF01073.14 EEQ72206.1 - 0.049 12.3 0.1 0.068 11.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Prenyltransf PF01255.14 EEQ72207.1 - 2.5e-82 275.3 0.0 3.7e-82 274.7 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Acyltransferase PF01553.16 EEQ72208.1 - 9.1e-10 38.0 0.0 9.6e-05 21.8 0.0 2.5 2 0 0 2 2 2 2 Acyltransferase DUF3710 PF12502.3 EEQ72208.1 - 0.0044 16.3 0.0 0.0076 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3710) DPM3 PF08285.6 EEQ72208.1 - 0.06 13.1 4.6 0.16 11.8 3.2 1.7 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Phage_GPO PF05929.6 EEQ72210.1 - 0.61 9.2 2.5 0.64 9.2 0.9 1.5 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4085 PF13315.1 EEQ72210.1 - 1.2 8.4 8.3 1.8 7.8 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) DUF342 PF03961.8 EEQ72210.1 - 1.7 6.9 3.3 2.4 6.4 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) WWbp PF10349.4 EEQ72211.1 - 1.2e-23 84.1 0.6 1.2e-23 84.1 0.4 1.9 2 0 0 2 2 2 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 EEQ72211.1 - 0.001 18.7 0.0 0.0034 17.1 0.0 1.8 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 EEQ72211.1 - 0.002 17.6 0.0 0.0035 16.8 0.0 1.5 1 0 0 1 1 1 1 GRAM domain UCR_hinge PF02320.11 EEQ72212.1 - 4.1e-23 81.0 4.8 9.1e-23 79.9 3.3 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein OAD_gamma PF04277.8 EEQ72212.1 - 0.17 12.3 1.6 0.26 11.6 1.1 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Adeno_terminal PF02459.10 EEQ72212.1 - 0.32 9.1 5.9 0.42 8.7 4.1 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Sigma70_ner PF04546.8 EEQ72212.1 - 0.47 10.0 6.6 0.64 9.6 4.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF3306 PF11748.3 EEQ72212.1 - 5.2 7.7 9.3 9.6 6.8 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) MFS_1 PF07690.11 EEQ72213.1 - 8.8e-25 87.1 32.4 1.3e-24 86.6 22.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily PNTB PF02233.11 EEQ72213.1 - 0.038 12.7 1.0 0.064 12.0 0.7 1.3 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit Uds1 PF15456.1 EEQ72215.1 - 5.3e-45 152.4 5.4 5.3e-45 152.4 3.8 6.6 4 3 1 5 5 5 1 Up-regulated During Septation Prp19 PF08606.6 EEQ72215.1 - 0.0031 17.1 0.7 0.0031 17.1 0.5 4.3 5 0 0 5 5 5 1 Prp19/Pso4-like DUF3138 PF11336.3 EEQ72215.1 - 0.53 8.4 1.7 1.6 6.7 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) FlaC_arch PF05377.6 EEQ72215.1 - 2 8.4 16.0 7.2 6.5 0.1 5.9 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) WD40 PF00400.27 EEQ72219.1 - 7.6e-41 136.5 11.2 4.7e-07 29.4 0.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EEQ72219.1 - 1.9e-12 46.6 0.9 4.1e-12 45.6 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ72219.1 - 1.2e-07 31.1 0.2 2.5e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EEQ72219.1 - 1.8e-05 23.0 1.8 0.14 10.3 0.0 3.0 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PH_10 PF15411.1 EEQ72220.1 - 1.2e-35 122.1 0.0 3.6e-32 110.9 0.0 2.6 2 0 0 2 2 2 2 Pleckstrin homology domain CDC24 PF06395.6 EEQ72220.1 - 2.8e-34 117.0 0.0 5.4e-34 116.1 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.15 EEQ72220.1 - 3.4e-31 108.4 1.1 5.9e-31 107.7 0.7 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.19 EEQ72220.1 - 3.1e-09 36.3 0.1 8.9e-09 34.9 0.0 1.9 1 0 0 1 1 1 1 PB1 domain CytochromB561_N PF09786.4 EEQ72220.1 - 0.82 8.0 5.4 1 7.6 2.0 2.0 2 0 0 2 2 2 0 Cytochrome B561, N terminal Aminotran_1_2 PF00155.16 EEQ72221.1 - 4.1e-36 124.7 0.0 5e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4129 PF13559.1 EEQ72222.1 - 0.0054 16.6 0.1 0.032 14.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4129) 2-Hacid_dh_C PF02826.14 EEQ72223.1 - 7.9e-17 60.9 0.2 2e-09 36.8 0.1 2.3 1 1 1 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gram_pos_anchor PF00746.16 EEQ72223.1 - 0.051 13.3 0.1 0.051 13.3 0.0 2.4 2 0 0 2 2 2 0 Gram positive anchor Suc_Fer-like PF06999.7 EEQ72224.1 - 2e-34 119.6 0.0 1.2e-33 117.0 0.0 2.0 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Opiods_neuropep PF01160.13 EEQ72224.1 - 0.57 9.9 3.1 0.37 10.5 0.5 1.9 2 0 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide zf-H2C2_2 PF13465.1 EEQ72225.1 - 9.8e-16 57.1 32.3 2e-07 30.9 0.6 5.3 5 1 1 6 6 6 3 Zinc-finger double domain zf-C2H2 PF00096.21 EEQ72225.1 - 2.7e-13 49.3 35.9 0.00013 22.1 0.8 4.6 4 1 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ72225.1 - 0.00011 22.2 29.6 0.19 12.1 1.2 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger BolA PF01722.13 EEQ72225.1 - 0.03 14.2 3.0 0.65 9.9 0.2 2.8 3 0 0 3 3 3 0 BolA-like protein Peptidase_M41 PF01434.13 EEQ72229.1 - 3.8e-68 229.1 0.5 7.2e-68 228.2 0.4 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EEQ72229.1 - 2.2e-43 147.6 0.0 6e-43 146.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEQ72229.1 - 1.7e-06 28.1 0.0 6e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EEQ72229.1 - 1.3e-05 26.0 0.0 3.5e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEQ72229.1 - 1.4e-05 24.8 0.0 4.8e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EEQ72229.1 - 3.4e-05 22.7 0.2 7.6e-05 21.6 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus AAA_22 PF13401.1 EEQ72229.1 - 4e-05 23.7 2.1 0.0025 17.9 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EEQ72229.1 - 0.00013 21.3 1.0 0.031 13.6 0.2 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EEQ72229.1 - 0.00043 19.3 0.0 0.00098 18.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EEQ72229.1 - 0.0017 18.0 0.5 0.0054 16.4 0.4 1.8 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EEQ72229.1 - 0.0018 17.7 0.0 0.0036 16.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EEQ72229.1 - 0.0019 18.0 0.0 0.005 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EEQ72229.1 - 0.004 16.3 2.4 1.2 8.2 0.0 3.5 4 0 0 4 4 4 1 KaiC Zeta_toxin PF06414.7 EEQ72229.1 - 0.0054 15.8 0.4 0.016 14.3 0.2 1.9 1 1 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 EEQ72229.1 - 0.0069 16.2 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EEQ72229.1 - 0.0081 15.1 0.0 0.017 14.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 EEQ72229.1 - 0.015 15.2 0.0 0.046 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) NACHT PF05729.7 EEQ72229.1 - 0.015 14.9 0.3 1.2 8.8 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 EEQ72229.1 - 0.017 15.1 0.5 0.04 13.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 EEQ72229.1 - 0.02 14.0 0.2 0.04 13.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EEQ72229.1 - 0.042 14.1 0.0 0.14 12.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain Imm41 PF15583.1 EEQ72229.1 - 0.082 12.7 0.2 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 41 NTP_transferase PF00483.18 EEQ72231.1 - 6.7e-48 163.1 0.0 1.6e-47 161.9 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 EEQ72231.1 - 7.1e-14 50.5 10.8 5e-10 38.4 1.9 4.0 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EEQ72231.1 - 4.3e-10 39.9 0.0 6.4e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EEQ72231.1 - 5e-07 29.1 2.0 5e-07 29.1 1.4 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 EEQ72231.1 - 0.067 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase adh_short PF00106.20 EEQ72232.1 - 3.8e-05 23.6 0.0 0.0018 18.2 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EEQ72232.1 - 0.043 13.4 0.0 0.089 12.4 0.0 1.5 1 0 0 1 1 1 0 KR domain Nitrate_red_gam PF02665.9 EEQ72233.1 - 0.049 12.9 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit CC PF04942.9 EEQ72233.1 - 0.36 10.7 13.2 0.13 12.1 4.8 3.0 2 1 0 2 2 2 0 CC domain FGGY_C PF02782.11 EEQ72235.1 - 2e-71 239.7 0.1 3.2e-71 239.0 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EEQ72235.1 - 1.6e-65 220.8 0.1 2.1e-65 220.4 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 EEQ72235.1 - 0.00049 19.4 0.8 0.12 11.6 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family ROK PF00480.15 EEQ72235.1 - 0.022 14.6 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 ROK family Stimulus_sens_1 PF13756.1 EEQ72235.1 - 0.07 13.5 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 Stimulus-sensing domain RCR PF12273.3 EEQ72236.1 - 0.041 14.4 0.9 8.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Cytochrom_CIII PF02085.11 EEQ72236.1 - 0.086 12.9 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Class III cytochrome C family DUF3429 PF11911.3 EEQ72237.1 - 6.9e-43 146.0 11.2 1e-42 145.4 7.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) DUF1162 PF06650.7 EEQ72239.1 - 1.6e-84 283.3 0.0 3.3e-83 279.0 0.0 3.0 4 0 0 4 4 4 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EEQ72239.1 - 9.5e-42 141.2 0.0 2.5e-41 139.9 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EEQ72239.1 - 5.4e-06 26.4 0.2 2.4e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 ATG C terminal domain GCFC PF07842.7 EEQ72240.1 - 1.1e-92 310.3 7.5 1.9e-92 309.5 5.2 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EEQ72240.1 - 4.8e-15 55.0 2.4 1.1e-14 53.8 1.7 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EEQ72240.1 - 2.8e-07 30.2 0.6 8e-07 28.8 0.4 1.8 1 0 0 1 1 1 1 DExH-box splicing factor binding site UPF0122 PF04297.9 EEQ72240.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like Sod_Fe_C PF02777.13 EEQ72241.1 - 2.3e-39 133.5 0.3 4.3e-39 132.6 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EEQ72241.1 - 9.3e-29 99.5 1.4 1.5e-28 98.8 1.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Imm15 PF15590.1 EEQ72241.1 - 1.3 8.1 6.6 2.1 7.4 0.2 3.4 2 2 2 4 4 4 0 Immunity protein 15 Microtub_assoc PF07989.6 EEQ72242.1 - 0.12 12.2 14.3 0.14 11.9 7.5 2.3 1 1 1 2 2 2 0 Microtubule associated AAA_27 PF13514.1 EEQ72242.1 - 0.12 10.0 9.0 0.16 9.6 6.2 1.1 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EEQ72242.1 - 0.16 12.3 7.2 0.33 11.2 5.0 1.5 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 EEQ72242.1 - 1.1 8.1 11.7 1.9 7.4 8.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EEQ72242.1 - 1.7 8.2 15.2 3 7.4 10.5 1.4 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 EEQ72242.1 - 3.9 7.8 11.6 3.1 8.1 5.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Sld5 PF05916.6 EEQ72243.1 - 2.3e-16 60.0 0.0 2.9e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein DUF3963 PF13124.1 EEQ72245.1 - 0.0076 16.0 0.3 0.016 15.0 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3963) Crystall_3 PF08964.5 EEQ72245.1 - 0.023 14.4 0.3 6 6.6 0.0 2.8 2 0 0 2 2 2 0 Beta/Gamma crystallin Topoisom_bac PF01131.15 EEQ72246.1 - 1.7e-86 290.6 0.0 4.6e-81 272.6 0.0 2.0 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 EEQ72246.1 - 3.9e-13 49.2 0.0 8.2e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Rieske PF00355.21 EEQ72247.1 - 0.078 12.5 0.9 0.14 11.6 0.6 1.4 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain WTF PF03303.8 EEQ72250.1 - 0.038 13.3 1.9 0.073 12.4 1.3 1.3 1 0 0 1 1 1 0 WTF protein Transket_pyr PF02779.19 EEQ72251.1 - 6.1e-65 218.0 0.0 9.5e-65 217.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EEQ72251.1 - 1.1e-54 185.1 0.0 1.6e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF2247 PF10004.4 EEQ72251.1 - 0.055 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) ING PF12998.2 EEQ72252.1 - 2.6e-07 30.8 0.0 4.3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EEQ72252.1 - 3e-05 23.5 3.8 5e-05 22.8 2.7 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EEQ72252.1 - 0.015 15.3 0.2 0.029 14.5 0.1 1.3 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF1751 PF08551.5 EEQ72253.1 - 0.011 16.1 2.0 0.011 16.1 0.1 1.9 1 1 1 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) BSD PF03909.12 EEQ72255.1 - 8.2e-28 95.9 12.7 4.3e-15 55.1 0.3 3.3 4 0 0 4 4 4 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EEQ72255.1 - 4.7e-14 51.7 1.8 1.4e-13 50.3 0.1 2.4 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain F-box-like PF12937.2 EEQ72256.1 - 0.00019 21.0 0.2 0.00051 19.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.28 EEQ72256.1 - 0.0067 16.3 3.7 60 4.2 0.0 5.9 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.1 EEQ72256.1 - 0.0076 16.2 2.3 9.9 6.5 0.0 5.1 5 0 0 5 5 5 1 Leucine Rich repeat APH PF01636.18 EEQ72257.1 - 0.0087 15.8 0.0 0.013 15.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Hus1 PF04005.7 EEQ72258.1 - 0.044 12.7 0.2 0.051 12.5 0.1 1.1 1 0 0 1 1 1 0 Hus1-like protein Hydrolase_6 PF13344.1 EEQ72259.1 - 7.1e-20 70.7 0.0 1.3e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ72259.1 - 2.4e-17 62.3 0.1 9.6e-17 60.4 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EEQ72259.1 - 0.00023 21.4 0.0 0.022 14.9 0.0 2.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEQ72259.1 - 0.017 15.5 0.0 0.55 10.6 0.0 2.7 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Apt1 PF10351.4 EEQ72259.1 - 0.05 12.4 0.0 0.4 9.4 0.0 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain TC1 PF15063.1 EEQ72259.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 Thyroid cancer protein 1 PGP_phosphatase PF09419.5 EEQ72259.1 - 0.15 11.3 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Aldo_ket_red PF00248.16 EEQ72261.1 - 7.8e-55 185.6 0.0 9.3e-55 185.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SUZ PF12752.2 EEQ72264.1 - 0.0031 18.0 5.6 0.0031 18.0 3.9 4.5 3 1 1 4 4 4 1 SUZ domain SUZ-C PF12901.2 EEQ72264.1 - 0.01 15.4 4.8 0.01 15.4 3.4 2.9 2 0 0 2 2 2 0 SUZ-C motif NUP50 PF08911.6 EEQ72264.1 - 0.012 15.9 0.4 0.012 15.9 0.3 4.0 4 0 0 4 4 4 0 NUP50 (Nucleoporin 50 kDa) Macoilin PF09726.4 EEQ72264.1 - 7.5 4.6 14.1 0.16 10.2 5.2 1.5 2 0 0 2 2 2 0 Transmembrane protein GST_N_3 PF13417.1 EEQ72265.1 - 1e-23 83.2 0.0 2.2e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEQ72265.1 - 8.8e-15 54.4 0.0 2.3e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEQ72265.1 - 4.1e-06 26.5 0.1 1e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EEQ72265.1 - 0.012 15.6 0.0 0.03 14.2 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin DUF1471 PF07338.8 EEQ72265.1 - 0.21 11.2 0.7 0.6 9.8 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) ATP_bind_1 PF03029.12 EEQ72267.1 - 1.8e-74 250.2 0.0 2.4e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EEQ72267.1 - 5.5e-06 25.9 0.0 0.00072 19.0 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 EEQ72267.1 - 7.2e-06 24.9 0.0 0.0065 15.2 0.0 2.3 2 0 0 2 2 2 2 ArgK protein MMR_HSR1 PF01926.18 EEQ72267.1 - 0.0003 20.7 0.0 0.0014 18.5 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EEQ72267.1 - 0.00057 20.0 0.0 0.0019 18.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EEQ72267.1 - 0.0012 18.7 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arf PF00025.16 EEQ72267.1 - 0.0017 17.6 0.0 1.4 8.1 0.0 3.2 3 0 0 3 3 3 1 ADP-ribosylation factor family NACHT PF05729.7 EEQ72267.1 - 0.0018 17.9 0.0 0.0054 16.4 0.0 1.7 2 0 0 2 2 2 1 NACHT domain cobW PF02492.14 EEQ72267.1 - 0.0021 17.5 0.0 0.64 9.4 0.0 2.5 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 EEQ72267.1 - 0.0024 17.3 0.0 0.04 13.3 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Miro PF08477.8 EEQ72267.1 - 0.0034 17.8 0.0 3.3 8.2 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 EEQ72267.1 - 0.0038 16.7 0.0 0.0057 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA-like domain FeoB_N PF02421.13 EEQ72267.1 - 0.004 16.4 0.0 0.18 11.0 0.0 2.8 3 0 0 3 3 3 1 Ferrous iron transport protein B PRK PF00485.13 EEQ72267.1 - 0.0042 16.6 0.0 0.088 12.3 0.0 2.2 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EEQ72267.1 - 0.0042 17.8 2.5 0.0058 17.4 0.0 2.3 2 1 0 2 2 1 1 AAA domain MobB PF03205.9 EEQ72267.1 - 0.0086 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EEQ72267.1 - 0.01 14.6 0.0 0.019 13.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 EEQ72267.1 - 0.012 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 EEQ72267.1 - 0.017 14.6 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EEQ72267.1 - 0.018 14.5 0.1 0.69 9.4 0.0 2.9 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation CbiA PF01656.18 EEQ72267.1 - 0.021 14.2 0.0 0.07 12.5 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain G-alpha PF00503.15 EEQ72267.1 - 0.031 12.9 0.0 3.9 6.0 0.0 2.6 2 0 0 2 2 2 0 G-protein alpha subunit Thymidylate_kin PF02223.12 EEQ72267.1 - 0.038 13.3 0.0 0.42 9.9 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase Zeta_toxin PF06414.7 EEQ72267.1 - 0.062 12.3 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin CwfJ_C_1 PF04677.10 EEQ72268.1 - 2.6e-32 111.0 0.0 3.1e-31 107.5 0.0 2.2 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EEQ72268.1 - 1.5e-27 95.9 0.1 7.1e-27 93.7 0.0 2.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 2-Hacid_dh_C PF02826.14 EEQ72269.1 - 7.3e-56 188.1 0.0 9.7e-56 187.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEQ72269.1 - 1e-14 54.1 0.0 1.3e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EEQ72269.1 - 0.00011 22.1 0.1 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EEQ72269.1 - 0.015 14.6 0.1 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Zn_clus PF00172.13 EEQ72270.1 - 1.3e-08 34.5 10.5 2.2e-08 33.8 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.8 EEQ72270.1 - 1.8 8.3 11.1 2.9 7.6 7.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-U1 PF06220.7 EEQ72271.1 - 1.7e-08 33.8 0.6 2.9e-08 33.1 0.4 1.4 1 0 0 1 1 1 1 U1 zinc finger DUF2951 PF11166.3 EEQ72271.1 - 1.1 9.1 4.2 0.78 9.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) CAP_GLY PF01302.20 EEQ72272.1 - 3.1e-20 71.6 0.1 5.4e-20 70.8 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 EEQ72272.1 - 2.8e-18 65.1 7.2 5.8e-05 22.6 0.1 5.2 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EEQ72272.1 - 8.8e-10 37.2 6.4 1.2 9.4 0.1 7.5 6 1 1 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.1 EEQ72272.1 - 1.2e-09 37.7 5.4 0.00035 20.2 0.2 4.5 3 2 2 5 5 5 4 Leucine rich repeat LRR_6 PF13516.1 EEQ72272.1 - 6.9e-09 34.8 1.4 14 6.1 0.1 7.3 7 0 0 7 7 7 2 Leucine Rich repeat LRR_7 PF13504.1 EEQ72272.1 - 1.9e-06 27.0 8.1 0.22 11.8 0.1 6.9 5 1 1 6 6 6 1 Leucine rich repeat zf-met PF12874.2 EEQ72273.1 - 1.8e-05 24.7 0.6 3.7e-05 23.7 0.4 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DNA_ligase_OB_2 PF14743.1 EEQ72273.1 - 0.033 13.8 0.1 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 DNA ligase OB-like domain PRP4 PF08799.6 EEQ72273.1 - 0.052 12.8 0.9 0.093 12.0 0.6 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Pkinase PF00069.20 EEQ72274.1 - 1.1e-54 185.3 0.1 2.5e-38 131.7 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ72274.1 - 9.7e-25 87.1 0.3 2.6e-19 69.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEQ72274.1 - 0.00016 20.7 0.0 0.00043 19.3 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEQ72274.1 - 0.00031 19.8 0.0 0.00065 18.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ72274.1 - 0.00042 20.1 0.2 0.019 14.6 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EEQ72274.1 - 0.015 14.1 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_C PF00433.19 EEQ72274.1 - 0.045 14.2 0.3 0.15 12.6 0.0 2.1 2 0 0 2 2 2 0 Protein kinase C terminal domain RIO1 PF01163.17 EEQ72274.1 - 0.066 12.5 0.9 0.16 11.2 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.6 EEQ72274.1 - 0.076 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Tim54 PF11711.3 EEQ72275.1 - 1e-137 458.8 0.5 1.3e-137 458.4 0.3 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 NARP1 PF12569.3 EEQ72276.1 - 2.5e-211 702.9 16.5 8.5e-211 701.1 6.3 2.4 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_14 PF13428.1 EEQ72276.1 - 4e-23 79.7 13.4 0.0004 20.7 0.1 10.0 8 2 2 10 10 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ72276.1 - 1.3e-22 79.2 24.6 1.6e-06 27.6 0.8 7.4 5 2 4 9 9 8 6 TPR repeat TPR_2 PF07719.12 EEQ72276.1 - 3.4e-21 73.4 18.5 2.4e-06 27.0 0.1 10.6 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ72276.1 - 4.7e-20 71.7 23.3 0.00034 21.1 0.0 8.2 8 1 0 9 9 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ72276.1 - 1.7e-19 69.9 20.4 0.0011 19.2 0.9 7.1 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ72276.1 - 9.7e-13 47.2 11.3 0.1 12.8 0.0 8.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ72276.1 - 1.9e-12 46.1 20.3 1e-05 24.8 0.3 8.6 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ72276.1 - 1.8e-11 43.7 12.9 0.00049 19.9 0.5 7.0 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ72276.1 - 2e-11 42.7 11.9 0.00027 20.4 0.1 7.2 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ72276.1 - 7.5e-08 32.1 7.2 0.00018 21.2 0.4 5.7 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ72276.1 - 1.4e-07 30.8 11.3 0.031 14.0 0.1 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EEQ72276.1 - 6.6e-06 26.1 13.6 0.057 13.5 1.7 5.2 3 2 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EEQ72276.1 - 0.00035 19.7 14.2 0.031 13.3 1.1 4.4 1 1 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ72276.1 - 0.0016 18.8 20.4 0.87 10.1 0.1 7.6 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_21 PF09976.4 EEQ72276.1 - 0.0041 17.0 13.6 0.0053 16.7 0.1 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.12 EEQ72276.1 - 0.0045 17.2 0.3 0.0045 17.2 0.2 3.3 4 0 0 4 4 4 1 Bacterial transcriptional activator domain TPR_4 PF07721.9 EEQ72276.1 - 0.018 15.4 14.8 2.5 8.7 0.1 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_5 PF12688.2 EEQ72276.1 - 0.026 14.5 1.1 0.26 11.3 0.0 3.1 3 1 0 3 3 3 0 Tetratrico peptide repeat TPR_10 PF13374.1 EEQ72276.1 - 4 7.5 19.8 13 5.9 1.2 6.4 8 0 0 8 8 7 0 Tetratricopeptide repeat PI-PLC-X PF00388.14 EEQ72277.1 - 5.3e-11 42.1 0.0 1.5e-10 40.6 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain DsrD PF08679.6 EEQ72277.1 - 0.052 13.5 0.2 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) Glycos_transf_3 PF00591.16 EEQ72279.1 - 1.7e-60 204.5 0.0 5e-50 170.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EEQ72279.1 - 2e-06 27.2 0.7 3.5e-06 26.5 0.5 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DNA_RNApol_7kD PF03604.8 EEQ72280.1 - 9.6e-17 60.1 6.9 1.2e-16 59.8 4.8 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 EEQ72280.1 - 0.0018 17.9 0.1 0.0018 17.9 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DUF2197 PF09963.4 EEQ72280.1 - 0.0026 17.6 1.6 0.17 11.8 0.1 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2197) A2L_zn_ribbon PF08792.5 EEQ72280.1 - 0.0032 16.8 2.5 0.22 11.0 0.1 2.1 2 0 0 2 2 2 1 A2L zinc ribbon domain DUF2318 PF10080.4 EEQ72280.1 - 0.0051 16.5 0.2 0.0055 16.4 0.1 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) DZR PF12773.2 EEQ72280.1 - 0.0051 16.6 0.4 0.0072 16.1 0.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon Zn-ribbon_8 PF09723.5 EEQ72280.1 - 0.0075 16.2 1.8 0.013 15.4 1.3 1.4 1 0 0 1 1 1 1 Zinc ribbon domain Rubredoxin PF00301.15 EEQ72280.1 - 0.023 14.5 0.0 0.75 9.7 0.0 2.1 2 0 0 2 2 2 0 Rubredoxin TFIIS_C PF01096.13 EEQ72280.1 - 0.028 14.0 1.1 3.2 7.4 0.2 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF3268 PF11672.3 EEQ72280.1 - 0.039 14.0 0.7 0.82 9.7 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3268) GFA PF04828.9 EEQ72280.1 - 0.057 13.3 1.0 6 6.8 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF2082 PF09855.4 EEQ72280.1 - 0.075 12.8 0.7 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) OrfB_Zn_ribbon PF07282.6 EEQ72280.1 - 0.14 11.8 0.9 0.2 11.3 0.7 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.2 EEQ72280.1 - 0.26 11.1 3.7 1.1 9.1 0.3 1.9 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DUF951 PF06107.6 EEQ72280.1 - 0.27 10.7 3.2 1.2 8.6 0.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) Ribosomal_L40e PF01020.12 EEQ72280.1 - 0.3 10.7 2.9 0.43 10.2 2.0 1.2 1 0 0 1 1 1 0 Ribosomal L40e family RRN7 PF11781.3 EEQ72280.1 - 0.3 10.6 0.2 0.3 10.6 0.1 2.1 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-trcl PF13451.1 EEQ72280.1 - 0.57 9.8 3.0 2.1 8.0 0.1 2.1 1 1 1 2 2 2 0 Probable zinc-binding domain TF_Zn_Ribbon PF08271.7 EEQ72280.1 - 1 8.7 5.2 8.4 5.7 0.3 2.2 1 1 2 3 3 3 0 TFIIB zinc-binding Zn_ribbon_recom PF13408.1 EEQ72280.1 - 1.2 9.4 6.6 3.8 7.8 0.6 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain zf-DNL PF05180.7 EEQ72280.1 - 2.2 8.0 4.9 8.2 6.2 0.1 2.4 2 1 1 3 3 3 0 DNL zinc finger T2SK PF03934.8 EEQ72281.1 - 0.069 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K Fe_hyd_lg_C PF02906.9 EEQ72282.1 - 3.6e-62 210.2 0.0 6.9e-62 209.2 0.0 1.5 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain AA_permease_2 PF13520.1 EEQ72284.1 - 2e-63 214.4 46.9 2.5e-63 214.0 32.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ72284.1 - 4.3e-20 71.4 38.1 5.9e-20 71.0 26.4 1.1 1 0 0 1 1 1 1 Amino acid permease ACBP PF00887.14 EEQ72285.1 - 7e-27 92.9 0.6 8e-27 92.7 0.4 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein DUF1436 PF07262.6 EEQ72285.1 - 0.21 11.0 1.1 0.37 10.2 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1436) U-box PF04564.10 EEQ72286.1 - 2.9e-24 84.8 0.1 4.9e-24 84.0 0.1 1.4 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 EEQ72286.1 - 9.8e-17 60.3 8.4 2.3e-16 59.1 0.3 3.1 2 1 2 4 4 4 1 TPR repeat TPR_2 PF07719.12 EEQ72286.1 - 9.8e-09 34.4 8.5 0.0048 16.7 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ72286.1 - 1.9e-07 31.5 8.6 0.0016 19.0 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ72286.1 - 6.5e-06 25.5 5.3 0.0011 18.4 0.2 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ72286.1 - 0.00014 21.8 1.8 0.00044 20.2 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ72286.1 - 0.0066 16.3 6.0 0.046 13.6 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat zf-Nse PF11789.3 EEQ72286.1 - 0.0078 15.7 0.1 0.027 14.0 0.1 1.8 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit GvpG PF05120.7 EEQ72286.1 - 0.0092 15.7 1.7 0.023 14.4 1.2 1.7 1 0 0 1 1 1 1 Gas vesicle protein G TPR_19 PF14559.1 EEQ72286.1 - 0.013 15.7 2.9 0.057 13.7 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ72286.1 - 0.02 14.7 0.1 0.46 10.3 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ72286.1 - 0.028 15.0 8.1 0.35 11.6 0.0 3.9 2 1 2 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EEQ72286.1 - 0.047 13.8 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 GTPase_Cys_C PF12631.2 EEQ72286.1 - 0.12 12.8 0.7 0.25 11.7 0.5 1.6 1 0 0 1 1 1 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE zf-RING_UBOX PF13445.1 EEQ72286.1 - 0.19 11.5 0.0 0.6 9.8 0.0 1.9 1 1 0 1 1 1 0 RING-type zinc-finger DUF928 PF06051.7 EEQ72286.1 - 0.22 11.0 1.3 0.34 10.4 0.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) TPR_7 PF13176.1 EEQ72286.1 - 0.51 10.2 4.0 0.82 9.6 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat APH PF01636.18 EEQ72287.1 - 2.4e-07 30.7 0.0 3.4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EEQ72287.1 - 0.065 12.3 0.0 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Cupredoxin_1 PF13473.1 EEQ72287.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Cupredoxin-like domain TIM PF00121.13 EEQ72288.1 - 8.4e-44 149.4 0.0 1.7e-43 148.4 0.0 1.4 1 1 0 1 1 1 1 Triosephosphate isomerase IL13 PF03487.8 EEQ72288.1 - 0.054 13.2 2.0 0.057 13.1 0.2 1.9 2 0 0 2 2 2 0 Interleukin-13 LacAB_rpiB PF02502.13 EEQ72289.1 - 6.3e-42 142.5 0.2 7.2e-42 142.3 0.2 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.1 EEQ72289.1 - 0.03 14.2 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Glycine-rich SFCGS DHO_dh PF01180.16 EEQ72290.1 - 4.4e-60 203.1 0.2 6.1e-52 176.4 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.12 EEQ72290.1 - 1e-05 24.9 0.1 0.05 12.8 0.0 2.7 3 0 0 3 3 3 2 PcrB family FMN_dh PF01070.13 EEQ72290.1 - 0.0036 16.1 0.3 0.034 13.0 0.3 2.4 3 1 0 3 3 3 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EEQ72290.1 - 0.008 15.1 0.5 0.022 13.6 0.1 1.8 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Fungal_trans PF04082.13 EEQ72293.1 - 2.2e-16 59.5 0.1 5.4e-16 58.2 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EEQ72293.1 - 1.1e-07 31.7 8.6 2e-05 24.6 1.1 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEQ72293.1 - 9.1e-06 25.6 13.9 0.00039 20.5 4.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EEQ72293.1 - 0.0013 18.8 5.0 0.0026 17.8 3.5 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EEQ72293.1 - 0.013 15.7 16.8 0.037 14.3 4.6 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EEQ72293.1 - 0.016 15.3 4.7 0.12 12.5 0.7 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn_Tnp_IS1595 PF12760.2 EEQ72293.1 - 0.27 11.0 1.4 0.61 9.9 1.0 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.10 EEQ72293.1 - 1.1 9.0 7.8 0.39 10.5 0.7 2.4 2 0 0 2 2 2 0 BED zinc finger zf-met PF12874.2 EEQ72293.1 - 2.3 8.5 5.3 3.7 7.9 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Glypican PF01153.14 EEQ72294.1 - 0.011 14.3 0.1 0.011 14.3 0.1 1.0 1 0 0 1 1 1 0 Glypican PBP1_TM PF14812.1 EEQ72294.1 - 0.6 10.4 4.2 0.76 10.1 2.9 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 EEQ72294.1 - 4.2 5.9 12.5 4.9 5.7 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Bd3614-deam PF14439.1 EEQ72294.1 - 5.7 6.7 8.7 1.8 8.3 3.3 1.8 1 1 0 2 2 2 0 Bd3614-like deaminase QCR10 PF09796.4 EEQ72295.1 - 4.7e-28 96.6 0.3 5.3e-28 96.4 0.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Zip PF02535.17 EEQ72296.1 - 0.046 12.7 13.5 0.06 12.3 9.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3337 PF11816.3 EEQ72296.1 - 0.51 9.6 9.3 0.63 9.3 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) TFIIA PF03153.8 EEQ72296.1 - 2.1 8.1 22.0 2.6 7.8 15.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S64 PF08192.6 EEQ72296.1 - 8.1 4.6 13.0 9.6 4.3 9.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 KIAA1328 PF15369.1 EEQ72296.1 - 9.4 5.9 13.9 12 5.5 9.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Tyr-DNA_phospho PF06087.7 EEQ72297.1 - 4.1e-147 490.4 0.0 1.2e-146 488.9 0.0 1.7 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EEQ72297.1 - 0.0018 17.9 0.0 0.27 10.9 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain Nucleoplasmin PF03066.10 EEQ72297.1 - 0.0064 16.0 0.9 0.012 15.1 0.6 1.5 1 0 0 1 1 1 1 Nucleoplasmin Nop14 PF04147.7 EEQ72297.1 - 0.19 9.6 1.3 0.25 9.2 0.9 1.2 1 0 0 1 1 1 0 Nop14-like family Spt5_N PF11942.3 EEQ72297.1 - 5.2 7.7 14.0 1.1 9.9 6.9 1.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal APG5 PF04106.7 EEQ72298.1 - 1e-68 230.7 0.0 1.2e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 SAM_2 PF07647.12 EEQ72299.1 - 4.3e-10 39.3 0.0 7.3e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EEQ72299.1 - 2.6e-08 33.9 0.0 4.8e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 EEQ72299.1 - 3e-06 27.3 0.1 5.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 PH domain Ste50p-SAM PF09235.5 EEQ72299.1 - 0.015 15.2 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif PH_9 PF15410.1 EEQ72299.1 - 0.026 14.6 0.4 0.091 12.9 0.3 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.1 EEQ72299.1 - 0.043 14.0 0.2 0.13 12.4 0.2 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain PH_6 PF15406.1 EEQ72299.1 - 0.066 13.2 0.1 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain DUF3435 PF11917.3 EEQ72301.1 - 8.1e-122 406.9 0.2 5.3e-112 374.6 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) Fungal_trans_2 PF11951.3 EEQ72303.1 - 4.8e-84 282.1 0.3 6.3e-84 281.7 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ72303.1 - 9.1e-05 22.2 9.3 0.00021 21.1 6.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 EEQ72304.1 - 2.7e-29 99.9 15.1 5.3e-07 29.2 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat UAF_Rrn10 PF05234.6 EEQ72305.1 - 0.00014 21.8 0.0 0.00023 21.1 0.0 1.3 1 0 0 1 1 1 1 UAF complex subunit Rrn10 Mnd1 PF03962.10 EEQ72306.1 - 5.1e-42 143.6 1.0 6.4e-42 143.3 0.7 1.0 1 0 0 1 1 1 1 Mnd1 family DsrD PF08679.6 EEQ72306.1 - 0.024 14.6 0.3 0.085 12.8 0.0 1.9 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) Imm18 PF15566.1 EEQ72306.1 - 0.12 11.7 4.0 0.97 8.8 0.9 2.8 1 1 1 2 2 2 0 Immunity protein 18 Chromo PF00385.19 EEQ72308.1 - 0.0002 20.9 0.2 0.00035 20.1 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Kdo PF06293.9 EEQ72310.1 - 0.00034 19.7 0.2 0.0015 17.6 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ72310.1 - 0.0052 16.5 0.1 0.0052 16.5 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EEQ72310.1 - 0.016 14.3 0.0 0.037 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein kinase domain WEMBL PF05701.6 EEQ72310.1 - 0.017 13.6 10.7 0.026 12.9 7.4 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Pol_alpha_B_N PF08418.5 EEQ72314.1 - 0.19 11.2 1.4 0.21 11.0 0.9 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF3543 PF12063.3 EEQ72316.1 - 0.077 12.2 0.1 0.085 12.0 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) Pkinase PF00069.20 EEQ72317.1 - 7.6e-27 94.0 0.0 1.4e-26 93.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ72317.1 - 1.8e-07 30.5 0.0 1.1e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 EEQ72317.1 - 0.014 14.4 0.1 0.022 13.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AIPR PF10592.4 EEQ72319.1 - 0.091 12.0 0.1 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 AIPR protein 7TMR-DISM_7TM PF07695.6 EEQ72320.1 - 0.49 10.0 7.1 0.18 11.4 1.1 2.3 1 1 0 2 2 2 0 7TM diverse intracellular signalling LMP PF04778.7 EEQ72321.1 - 0.037 13.7 0.4 0.062 13.0 0.0 1.6 2 0 0 2 2 2 0 LMP repeated region DUF3069 PF11269.3 EEQ72321.1 - 0.048 13.7 0.2 0.8 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) Cytochrom_C552 PF02335.10 EEQ72321.1 - 0.061 12.0 0.7 0.096 11.3 0.5 1.2 1 0 0 1 1 1 0 Cytochrome c552 FliJ PF02050.11 EEQ72321.1 - 0.21 11.6 5.9 0.53 10.3 0.1 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein HBS1_N PF08938.5 EEQ72321.1 - 0.81 9.8 0.1 0.81 9.8 0.1 2.1 2 0 0 2 2 2 0 HBS1 N-terminus F-box-like PF12937.2 EEQ72322.1 - 0.00039 20.0 0.0 0.001 18.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ72322.1 - 0.0048 16.5 0.0 0.014 15.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 EEQ72322.1 - 0.066 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 PRANC domain Exo_endo_phos_2 PF14529.1 EEQ72324.1 - 1.3e-19 69.9 0.1 3.9e-19 68.4 0.1 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase HALZ PF02183.13 EEQ72324.1 - 1.3e-05 24.8 0.8 2.8e-05 23.7 0.5 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper Exo_endo_phos PF03372.18 EEQ72324.1 - 2.2e-05 24.5 0.1 4.7e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ATG16 PF08614.6 EEQ72324.1 - 0.028 14.2 0.8 0.028 14.2 0.6 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF904 PF06005.7 EEQ72324.1 - 0.073 13.3 1.0 0.23 11.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF972 PF06156.8 EEQ72324.1 - 0.09 13.1 0.1 0.09 13.1 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF972) TSC22 PF01166.13 EEQ72324.1 - 0.092 12.7 1.0 0.45 10.5 0.1 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family Kinesin-relat_1 PF12711.2 EEQ72324.1 - 0.11 12.9 0.1 0.11 12.9 0.1 2.1 3 0 0 3 3 3 0 Kinesin motor DivIVA PF05103.8 EEQ72324.1 - 0.24 11.4 2.8 7.4 6.6 0.1 2.6 2 0 0 2 2 2 0 DivIVA protein bZIP_1 PF00170.16 EEQ72324.1 - 3.1 7.8 6.4 0.31 11.0 0.4 2.3 2 0 0 2 2 2 0 bZIP transcription factor BA14K PF07886.6 EEQ72325.1 - 0.082 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 BA14K-like protein Med28 PF11594.3 EEQ72326.1 - 0.00036 20.7 0.3 0.0005 20.2 0.2 1.3 1 0 0 1 1 1 1 Mediator complex subunit 28 zf-C3HC4_3 PF13920.1 EEQ72326.1 - 0.0035 16.9 9.6 0.0068 16.0 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Muted PF14942.1 EEQ72326.1 - 0.018 14.8 0.3 0.024 14.5 0.2 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein ADIP PF11559.3 EEQ72326.1 - 0.018 14.9 0.3 0.027 14.3 0.2 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding zf-C3HC4 PF00097.20 EEQ72326.1 - 0.021 14.4 6.6 0.056 13.1 4.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PspA_IM30 PF04012.7 EEQ72326.1 - 0.023 14.0 0.3 0.031 13.6 0.2 1.1 1 0 0 1 1 1 0 PspA/IM30 family CCDC155 PF14662.1 EEQ72326.1 - 0.028 14.0 1.6 0.036 13.6 1.1 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 HAUS5 PF14817.1 EEQ72326.1 - 0.032 12.7 0.8 0.048 12.2 0.6 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 ATG16 PF08614.6 EEQ72326.1 - 0.033 14.0 0.6 0.045 13.5 0.4 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4201 PF13870.1 EEQ72326.1 - 0.033 13.6 1.3 0.042 13.2 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) zf-RING_5 PF14634.1 EEQ72326.1 - 0.038 13.7 8.0 0.038 13.7 5.5 1.7 1 1 0 1 1 1 0 zinc-RING finger domain FlaC_arch PF05377.6 EEQ72326.1 - 0.042 13.7 0.1 0.95 9.3 0.0 2.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) GAS PF13851.1 EEQ72326.1 - 0.075 12.2 0.3 0.11 11.6 0.2 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF641 PF04859.7 EEQ72326.1 - 0.1 12.3 0.4 0.14 11.9 0.2 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) zf-C3HC4_2 PF13923.1 EEQ72326.1 - 0.26 11.3 8.9 0.62 10.1 6.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ72326.1 - 0.3 10.9 10.9 0.76 9.6 7.5 1.7 1 0 0 1 1 1 0 Ring finger domain bZIP_1 PF00170.16 EEQ72326.1 - 0.39 10.7 1.9 1.8 8.5 0.1 2.1 1 1 1 2 2 2 0 bZIP transcription factor Lzipper-MIP1 PF14389.1 EEQ72326.1 - 0.39 10.8 5.6 5 7.2 3.9 2.2 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 bZIP_2 PF07716.10 EEQ72326.1 - 0.76 9.6 3.1 6 6.7 0.1 2.2 2 0 0 2 2 2 0 Basic region leucine zipper FRG1 PF06229.7 EEQ72328.1 - 0.018 14.4 0.3 0.031 13.7 0.2 1.3 1 0 0 1 1 1 0 FRG1-like family PEHE PF15275.1 EEQ72328.1 - 0.75 10.2 7.5 2.1 8.8 3.6 2.5 1 1 1 2 2 2 0 PEHE domain DUF4570 PF15134.1 EEQ72332.1 - 0.014 15.1 1.9 0.019 14.8 1.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4570) DUF4142 PF13628.1 EEQ72332.1 - 0.06 13.3 0.1 0.15 12.0 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4142) DUF4071 PF13281.1 EEQ72332.1 - 0.14 10.9 4.1 0.16 10.7 2.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) Flavoprotein PF02441.14 EEQ72334.1 - 4.7e-38 129.7 0.8 6.6e-38 129.2 0.2 1.5 2 0 0 2 2 2 1 Flavoprotein Arrestin_N PF00339.24 EEQ72335.1 - 8.8e-15 54.8 0.0 5.8e-14 52.1 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain PPI_Ypi1 PF07491.6 EEQ72335.1 - 0.066 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein phosphatase inhibitor Tyrosinase PF00264.15 EEQ72337.1 - 3.2e-57 194.2 1.4 5.3e-57 193.5 1.0 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Gal-bind_lectin PF00337.17 EEQ72337.1 - 1.2e-07 31.1 0.2 2.3e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 Galactoside-binding lectin SHR3_chaperone PF08229.6 EEQ72338.1 - 6e-82 273.3 0.0 6.6e-82 273.2 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 Toxin_22 PF08092.6 EEQ72343.1 - 0.042 13.6 1.5 0.091 12.6 1.1 1.5 1 0 0 1 1 1 0 Magi peptide toxin family ABC_membrane PF00664.18 EEQ72344.1 - 2e-55 188.1 37.2 5.2e-29 101.5 14.2 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EEQ72344.1 - 2.5e-47 160.6 0.1 2.1e-26 92.8 0.0 3.1 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EEQ72344.1 - 6.3e-08 32.9 0.8 0.18 11.7 0.0 4.3 2 2 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 EEQ72344.1 - 1.4e-06 28.2 0.1 0.041 13.8 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 EEQ72344.1 - 3.7e-06 27.4 2.0 0.02 15.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EEQ72344.1 - 6.2e-06 25.5 3.0 0.12 11.6 1.0 3.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain Miro PF08477.8 EEQ72344.1 - 6.9e-06 26.5 0.8 0.069 13.6 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EEQ72344.1 - 8.3e-06 25.2 0.3 0.14 11.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EEQ72344.1 - 2.9e-05 24.1 2.4 0.071 13.0 0.0 3.2 3 1 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 EEQ72344.1 - 5e-05 22.5 0.2 0.054 12.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EEQ72344.1 - 0.00012 22.8 0.0 1 10.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EEQ72344.1 - 0.00017 20.7 0.1 0.19 10.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Dynamin_N PF00350.18 EEQ72344.1 - 0.00096 19.0 3.1 0.042 13.6 0.1 2.8 2 0 0 2 2 2 1 Dynamin family AAA_15 PF13175.1 EEQ72344.1 - 0.0017 17.4 0.0 0.3 10.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EEQ72344.1 - 0.0024 17.3 0.0 1.1 8.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain ArgK PF03308.11 EEQ72344.1 - 0.0065 15.2 1.0 2.2 6.9 0.2 2.3 2 0 0 2 2 2 2 ArgK protein AAA_28 PF13521.1 EEQ72344.1 - 0.031 14.2 1.9 0.084 12.8 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.1 EEQ72344.1 - 0.04 14.2 0.4 7.6 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EEQ72344.1 - 0.049 13.8 0.2 4 7.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.8 EEQ72344.1 - 0.076 11.9 0.2 10 4.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA PF00004.24 EEQ72344.1 - 0.087 13.0 0.1 2.9 8.1 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 EEQ72344.1 - 0.088 12.2 0.3 9.9 5.5 0.2 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Arch_ATPase PF01637.13 EEQ72344.1 - 0.092 12.4 0.2 1.6 8.3 0.0 2.7 3 0 0 3 3 3 0 Archaeal ATPase AAA_30 PF13604.1 EEQ72344.1 - 0.097 12.2 0.6 4.6 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EEQ72344.1 - 0.17 12.0 3.5 8.3 6.5 0.0 3.6 3 1 0 3 3 2 0 AAA domain DUF87 PF01935.12 EEQ72344.1 - 0.18 11.5 2.9 0.28 10.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 ATP_bind_1 PF03029.12 EEQ72344.1 - 0.22 10.9 1.5 6.4 6.2 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Aminotran_3 PF00202.16 EEQ72346.1 - 9.1e-102 340.3 0.0 1.2e-101 340.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EEQ72346.1 - 0.12 11.2 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EEQ72346.1 - 0.13 11.3 0.0 0.39 9.8 0.0 1.7 2 1 0 2 2 2 0 Beta-eliminating lyase Glyco_transf_22 PF03901.12 EEQ72347.1 - 1e-67 228.9 20.3 6.1e-34 117.7 2.0 2.1 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family ArfGap PF01412.13 EEQ72348.1 - 3.2e-11 43.0 0.4 1.5e-05 24.7 0.1 2.6 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf UBA PF00627.26 EEQ72348.1 - 0.06 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain PHD PF00628.24 EEQ72352.1 - 4.8e-05 22.9 10.3 0.0001 21.9 7.1 1.6 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 EEQ72352.1 - 0.00018 21.8 0.1 0.00018 21.8 0.1 3.3 3 1 0 3 3 3 1 SET domain CDC73 PF05179.9 EEQ72353.1 - 1.4e-36 126.3 7.2 2.7e-35 122.0 3.2 3.0 2 1 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family RGS PF00615.14 EEQ72354.1 - 1.6e-30 105.6 0.0 3.9e-30 104.3 0.0 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 EEQ72354.1 - 6.2e-27 93.1 0.2 2.1e-21 75.4 0.0 3.1 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ORC4_C PF14629.1 EEQ72357.1 - 4.8e-59 199.1 0.0 6.8e-59 198.6 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EEQ72357.1 - 5e-18 65.7 0.5 2.7e-17 63.3 0.4 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EEQ72357.1 - 1.1e-06 28.8 0.0 4.3e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEQ72357.1 - 2.6e-05 24.3 0.0 6.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EEQ72357.1 - 5.8e-05 22.8 0.0 0.00018 21.2 0.0 1.8 1 1 0 1 1 1 1 NACHT domain DUF815 PF05673.8 EEQ72357.1 - 6.3e-05 22.0 0.0 0.0001 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 EEQ72357.1 - 7.7e-05 22.4 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase KAP_NTPase PF07693.9 EEQ72357.1 - 0.0017 17.4 0.0 0.0027 16.7 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain MSP1_C PF07462.6 EEQ72357.1 - 0.0088 14.4 0.5 0.019 13.3 0.4 1.5 1 0 0 1 1 1 1 Merozoite surface protein 1 (MSP1) C-terminus AAA_19 PF13245.1 EEQ72357.1 - 0.012 15.3 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 EEQ72357.1 - 0.018 14.5 0.2 0.06 12.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EEQ72357.1 - 0.065 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Mg_chelatase PF01078.16 EEQ72357.1 - 0.072 12.2 0.0 0.28 10.3 0.0 1.9 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EEQ72357.1 - 0.087 12.7 0.0 0.36 10.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain Daxx PF03344.10 EEQ72357.1 - 0.34 9.3 6.3 0.66 8.3 4.4 1.4 1 0 0 1 1 1 0 Daxx Family SURF2 PF05477.6 EEQ72357.1 - 1.4 7.9 5.1 2.6 7.0 3.6 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF742 PF05331.6 EEQ72358.1 - 0.096 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF742) 4HBT PF03061.17 EEQ72359.1 - 1e-11 44.7 0.1 1.4e-11 44.3 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EEQ72359.1 - 0.0014 18.4 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily NOT2_3_5 PF04153.13 EEQ72360.1 - 5.7e-35 120.1 0.2 5.7e-35 120.1 0.1 2.3 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family MRP-L47 PF06984.8 EEQ72361.1 - 4.5e-20 71.3 0.0 7.6e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) GDI PF00996.13 EEQ72362.1 - 1.7e-180 600.0 0.0 2.3e-180 599.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 EEQ72362.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SMC_N PF02463.14 EEQ72363.1 - 1.6e-69 233.4 2.8 5.6e-69 231.7 2.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EEQ72363.1 - 1.3e-22 79.9 1.1 5.9e-22 77.8 0.2 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EEQ72363.1 - 4.3e-13 49.8 4.9 1.6e-05 25.0 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EEQ72363.1 - 1.4e-11 45.1 11.5 1.4e-11 45.1 7.9 6.7 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.1 EEQ72363.1 - 0.00086 18.7 0.1 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EEQ72363.1 - 0.11 12.8 0.0 0.11 12.8 0.0 5.5 4 2 0 4 4 4 0 ABC transporter Reo_sigmaC PF04582.7 EEQ72363.1 - 4.2 6.4 29.6 1.2 8.2 5.4 5.8 3 2 4 7 7 7 0 Reovirus sigma C capsid protein HSBP1 PF06825.7 EEQ72363.1 - 9.5 5.8 17.9 0.2 11.2 0.2 4.5 4 0 0 4 4 4 0 Heat shock factor binding protein 1 Methyltransf_23 PF13489.1 EEQ72364.1 - 4.7e-08 32.9 0.0 8.5e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ72364.1 - 2.8e-07 30.9 0.0 5.1e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ72364.1 - 2e-06 27.4 0.0 3.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ72364.1 - 0.00054 20.4 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EEQ72364.1 - 0.00079 18.7 0.0 0.0018 17.5 0.0 1.5 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_25 PF13649.1 EEQ72364.1 - 0.006 16.9 0.0 0.016 15.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ72364.1 - 0.052 14.1 0.0 0.74 10.4 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain CUE PF02845.11 EEQ72365.1 - 1.7e-12 46.5 0.0 2.8e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 CUE domain Sld5 PF05916.6 EEQ72366.1 - 1.1e-29 102.8 0.0 1.9e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein DIE2_ALG10 PF04922.7 EEQ72367.1 - 4.2e-70 236.6 23.2 2.8e-68 230.6 16.1 2.9 1 1 0 1 1 1 1 DIE2/ALG10 family p450 PF00067.17 EEQ72369.1 - 3e-52 177.7 0.0 3.7e-52 177.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 EEQ72371.1 - 0.00024 20.8 5.6 0.59 10.1 0.0 5.7 6 1 0 6 6 6 1 WD domain, G-beta repeat SPT6_acidic PF14632.1 EEQ72371.1 - 1.1 9.4 19.7 0.37 10.9 11.6 1.6 2 0 0 2 2 2 0 Acidic N-terminal SPT6 CDC45 PF02724.9 EEQ72371.1 - 2.4 6.1 8.8 3.3 5.6 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Diphthamide_syn PF01866.12 EEQ72372.1 - 3.2e-51 174.3 0.0 6.7e-51 173.3 0.0 1.5 2 0 0 2 2 2 1 Putative diphthamide synthesis protein Methyltransf_12 PF08242.7 EEQ72375.1 - 1.1e-14 54.7 0.0 2.9e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ72375.1 - 7.5e-12 45.5 0.0 1.5e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ72375.1 - 8.1e-11 41.8 0.0 1.4e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ72375.1 - 6.9e-10 39.5 0.0 1.2e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ72375.1 - 1.4e-09 38.2 0.0 2.8e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ72375.1 - 3.6e-09 36.3 0.0 5.6e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ72375.1 - 7.5e-07 28.4 0.0 1.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EEQ72375.1 - 6.4e-05 22.9 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EEQ72375.1 - 7.5e-05 21.8 0.0 0.0012 17.8 0.0 2.0 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_24 PF13578.1 EEQ72375.1 - 0.00056 20.7 0.0 0.002 18.9 0.0 2.0 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EEQ72375.1 - 0.00099 18.7 0.0 0.068 12.7 0.0 2.2 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.9 EEQ72375.1 - 0.0029 17.0 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DUF3419 PF11899.3 EEQ72375.1 - 0.048 12.3 0.0 0.068 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Methyltransf_32 PF13679.1 EEQ72375.1 - 0.074 12.7 0.0 0.18 11.4 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.4 EEQ72375.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Sugar_tr PF00083.19 EEQ72376.1 - 2.9e-45 154.7 20.7 3.3e-33 114.9 8.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EEQ72376.1 - 0.00032 19.5 27.4 0.015 13.9 12.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 EEQ72377.1 - 2.1e-33 115.2 0.7 3.7e-33 114.4 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.8 EEQ72377.1 - 0.0015 18.4 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 Gal4-like dimerisation domain Zn_clus PF00172.13 EEQ72377.1 - 0.0016 18.3 2.8 0.003 17.4 1.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HlyIII PF03006.15 EEQ72378.1 - 6.9e-57 192.4 20.6 8.5e-57 192.1 14.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related SPC12 PF06645.8 EEQ72378.1 - 0.013 15.2 1.4 0.051 13.3 1.0 2.0 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Pkinase PF00069.20 EEQ72379.1 - 1.7e-08 33.9 0.3 3.5e-08 32.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 EEQ72379.1 - 5.8e-07 28.7 0.0 8.6e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ72379.1 - 1.5e-06 28.1 0.2 0.00081 19.1 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EEQ72379.1 - 0.00011 21.6 0.0 0.00024 20.4 0.0 1.6 1 1 0 1 1 1 1 RIO1 family WaaY PF06176.6 EEQ72379.1 - 0.0055 15.9 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) DUF3381 PF11861.3 EEQ72379.1 - 0.05 13.1 0.2 0.13 11.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) FimP PF09766.4 EEQ72380.1 - 3.7e-24 85.4 9.7 4.8e-24 85.1 6.7 1.2 1 0 0 1 1 1 1 Fms-interacting protein DUF4200 PF13863.1 EEQ72380.1 - 0.00085 19.2 8.6 0.16 11.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) K-box PF01486.12 EEQ72380.1 - 0.039 13.7 0.1 0.039 13.7 0.1 2.8 2 1 1 3 3 3 0 K-box region DUF972 PF06156.8 EEQ72380.1 - 0.3 11.4 6.1 2 8.7 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF349 PF03993.7 EEQ72380.1 - 1 9.5 8.7 0.14 12.2 3.2 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Pinin_SDK_memA PF04696.8 EEQ72380.1 - 1.1 8.8 7.8 1.1 8.8 3.1 2.0 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DivIC PF04977.10 EEQ72380.1 - 3.4 7.2 10.1 5.2 6.6 0.1 2.4 2 1 0 2 2 2 0 Septum formation initiator PIG-S PF10510.4 EEQ72381.1 - 1.8e-175 584.5 1.2 2.1e-175 584.2 0.8 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein DUF4118 PF13493.1 EEQ72382.1 - 0.0065 16.6 0.2 0.032 14.4 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4118) Granulin PF00396.13 EEQ72382.1 - 0.026 14.6 23.0 0.11 12.6 1.1 3.4 3 0 0 3 3 3 0 Granulin TMEM154 PF15102.1 EEQ72382.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Sod_Fe_C PF02777.13 EEQ72383.1 - 2.8e-16 59.2 0.0 7.7e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Invasin_D3 PF09134.5 EEQ72383.1 - 0.049 13.5 0.0 4.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Invasin, domain 3 Polyketide_cyc PF03364.15 EEQ72384.1 - 1.3e-22 80.1 0.0 1.8e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EEQ72384.1 - 0.0017 18.5 2.1 0.0054 16.9 1.5 1.7 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport ZZ PF00569.12 EEQ72386.1 - 3.3e-05 23.3 7.1 3.3e-05 23.3 4.9 2.4 2 0 0 2 2 2 1 Zinc finger, ZZ type JmjC PF02373.17 EEQ72386.1 - 8.3e-05 22.8 0.0 0.00019 21.6 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Baculo_IE-1 PF05290.6 EEQ72386.1 - 0.15 11.7 4.8 0.1 12.3 0.6 2.1 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Ank_2 PF12796.2 EEQ72387.1 - 8.5e-19 67.6 0.0 7.5e-10 39.0 0.0 3.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ72387.1 - 3.6e-17 61.2 0.7 1.6e-07 30.7 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 EEQ72387.1 - 6.3e-17 61.5 1.3 3e-08 33.9 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ72387.1 - 4.2e-13 48.1 0.1 7.2e-05 22.6 0.0 6.5 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.1 EEQ72387.1 - 7.5e-12 45.0 0.1 4e-06 26.8 0.0 5.4 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Sulfatase PF00884.18 EEQ72388.1 - 8.2e-18 64.6 0.2 1.5e-17 63.7 0.2 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EEQ72388.1 - 8e-07 28.7 0.1 1.6e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EEQ72388.1 - 0.053 11.9 0.3 0.087 11.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Lyase_1 PF00206.15 EEQ72389.1 - 3.1e-87 292.6 0.0 4.2e-87 292.2 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EEQ72389.1 - 4.9e-27 93.8 0.1 1.1e-26 92.6 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal AMP-binding PF00501.23 EEQ72390.1 - 2e-72 243.8 0.0 2.5e-72 243.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ72390.1 - 1.9e-09 38.3 0.1 4.2e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.16 EEQ72391.1 - 3.9e-44 151.0 0.0 4.8e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EEQ72391.1 - 6.3e-11 41.9 0.0 9.4e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EEQ72391.1 - 2e-06 26.3 0.0 2.8e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EEQ72391.1 - 5.9e-06 25.2 0.0 1.2e-05 24.2 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EEQ72391.1 - 0.0005 19.2 0.0 0.00079 18.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family ABC2_membrane PF01061.19 EEQ72392.1 - 2.5e-37 128.0 20.6 6.6e-37 126.7 14.3 1.8 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EEQ72392.1 - 1.2e-24 87.1 2.6 1.3e-24 87.1 0.0 2.0 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.2 EEQ72392.1 - 5.8e-10 38.7 13.4 1.1e-09 37.7 8.9 1.8 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.1 EEQ72392.1 - 9.8e-09 35.5 0.0 1.3e-07 31.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEQ72392.1 - 0.0025 17.7 0.0 0.0061 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EEQ72392.1 - 0.0033 16.8 0.1 0.077 12.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EEQ72392.1 - 0.0091 15.9 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EEQ72392.1 - 0.01 15.0 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 EEQ72392.1 - 0.012 14.6 0.0 1.3 7.9 0.0 2.2 1 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EEQ72392.1 - 0.015 14.7 0.1 0.032 13.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EEQ72392.1 - 0.016 14.8 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 EEQ72392.1 - 0.018 14.6 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 EEQ72392.1 - 0.021 14.9 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EEQ72392.1 - 0.035 13.5 0.0 0.096 12.1 0.0 1.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.1 EEQ72392.1 - 0.04 14.7 0.0 0.087 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain hEGF PF12661.2 EEQ72392.1 - 0.048 13.7 24.7 0.11 12.5 4.1 4.2 3 0 0 3 3 3 0 Human growth factor-like EGF AAA_28 PF13521.1 EEQ72392.1 - 0.084 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EEQ72392.1 - 0.1 12.8 0.1 0.27 11.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EEQ72392.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EEQ72392.1 - 0.12 12.1 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B F-box-like PF12937.2 EEQ72394.1 - 0.018 14.7 0.5 0.043 13.5 0.3 1.7 1 0 0 1 1 1 0 F-box-like NmrA PF05368.8 EEQ72395.1 - 0.0074 15.5 0.1 0.04 13.1 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family MFS_1 PF07690.11 EEQ72396.1 - 1.6e-05 23.7 39.1 0.00066 18.4 14.9 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cornichon PF03311.9 EEQ72397.1 - 4.8e-53 178.6 11.7 5.4e-53 178.5 8.1 1.0 1 0 0 1 1 1 1 Cornichon protein WD40 PF00400.27 EEQ72398.1 - 5.6e-39 130.6 10.0 2.5e-10 39.7 0.3 7.6 7 1 0 7 7 7 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EEQ72398.1 - 0.00016 21.2 0.0 0.0003 20.3 0.0 1.4 1 0 0 1 1 1 1 PQQ-like domain ZZ PF00569.12 EEQ72399.1 - 1.4e-11 43.7 4.8 2.5e-11 42.9 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.27 EEQ72399.1 - 6.1e-11 40.8 6.0 2.9e-05 23.0 0.4 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EEQ72399.1 - 3.3e-10 39.9 3.4 7.6e-10 38.7 1.9 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EEQ72399.1 - 1.5e-08 33.8 3.4 0.0011 18.6 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EEQ72399.1 - 2e-05 24.1 6.8 0.01 15.4 0.3 3.4 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 EEQ72399.1 - 0.0023 17.1 3.6 0.14 11.5 0.2 3.0 2 0 0 2 2 2 2 EF hand MFS_1 PF07690.11 EEQ72400.1 - 8.2e-43 146.4 55.9 2.4e-42 144.9 38.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ72400.1 - 9.5e-16 57.4 4.6 9.5e-16 57.4 3.2 3.4 2 1 1 3 3 3 1 Sugar (and other) transporter BPD_transp_1 PF00528.17 EEQ72401.1 - 0.058 12.9 8.7 0.072 12.5 6.1 1.2 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component GP41 PF00517.12 EEQ72401.1 - 4.8 6.6 5.6 6.1 6.3 3.9 1.1 1 0 0 1 1 1 0 Retroviral envelope protein HipA_C PF07804.7 EEQ72404.1 - 0.047 13.8 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 HipA-like C-terminal domain Protocadherin PF08374.6 EEQ72404.1 - 0.078 12.6 2.7 0.083 12.5 1.4 1.3 1 1 0 1 1 1 0 Protocadherin DnaJ PF00226.26 EEQ72405.1 - 7.8e-21 73.5 2.9 1.5e-20 72.6 2.0 1.5 1 0 0 1 1 1 1 DnaJ domain MAP1B_neuraxin PF00414.12 EEQ72405.1 - 0.014 14.6 1.6 0.014 14.6 1.1 3.4 3 0 0 3 3 3 0 Neuraxin and MAP1B repeat MIP-T3 PF10243.4 EEQ72405.1 - 8.8 4.6 32.8 15 3.9 22.8 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Herpes_gE PF02480.11 EEQ72406.1 - 0.00043 18.6 0.0 0.00058 18.2 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Pex14_N PF04695.8 EEQ72406.1 - 0.0054 16.7 0.4 0.01 15.8 0.3 1.4 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region RCR PF12273.3 EEQ72406.1 - 0.25 11.9 0.2 0.25 11.9 0.2 2.4 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF563 PF04577.9 EEQ72407.1 - 1.1e-32 113.6 0.1 1.7e-32 113.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Adaptin_N PF01602.15 EEQ72409.1 - 5.1e-141 470.5 2.4 6e-141 470.3 1.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EEQ72409.1 - 7.3e-19 68.1 0.0 1.4e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EEQ72409.1 - 1.8e-05 24.8 2.6 0.037 14.3 0.0 4.1 3 1 1 4 4 4 2 HEAT repeats TIP120 PF08623.5 EEQ72409.1 - 0.013 15.1 0.5 0.055 13.0 0.1 2.2 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) Cnd1 PF12717.2 EEQ72409.1 - 0.023 14.5 3.6 0.056 13.2 0.3 3.2 3 2 2 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EEQ72409.1 - 0.079 13.0 2.2 75 3.8 0.0 4.6 4 1 0 4 4 4 0 HEAT repeat MBOAT PF03062.14 EEQ72410.1 - 3.6e-32 111.7 24.1 1.8e-30 106.1 16.7 2.0 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Pex14_N PF04695.8 EEQ72410.1 - 0.0074 16.3 0.0 0.046 13.7 0.0 2.1 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region dDENN PF03455.14 EEQ72411.1 - 0.1 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 dDENN domain Beta-lactamase PF00144.19 EEQ72412.1 - 1.3e-39 136.1 0.0 8.5e-39 133.4 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase Peptidase_C11 PF03415.9 EEQ72412.1 - 0.19 10.6 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Clostripain family EamA PF00892.15 EEQ72413.1 - 1.9e-08 34.3 22.2 3.1e-05 24.0 1.2 3.1 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EEQ72413.1 - 4.4e-08 32.5 1.4 7.3e-08 31.8 1.0 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EEQ72413.1 - 5e-08 32.2 7.6 8.7e-08 31.4 5.3 1.3 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EEQ72413.1 - 7.8e-07 28.8 14.6 0.0049 16.5 0.4 2.5 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 EEQ72413.1 - 0.00057 20.0 4.3 0.00057 20.0 3.0 3.3 2 1 1 3 3 3 1 Multidrug resistance efflux transporter Med15_fungi PF05397.7 EEQ72414.1 - 7.5e-23 80.6 1.0 7.5e-23 80.6 0.7 4.1 5 0 0 5 5 5 1 Mediator complex subunit 15 LMBR1 PF04791.11 EEQ72415.1 - 2.9e-34 118.4 1.9 3.7e-34 118.1 1.3 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein IncA PF04156.9 EEQ72415.1 - 1.9 8.0 6.1 7.2 6.1 0.0 2.6 2 0 0 2 2 2 0 IncA protein BAG PF02179.11 EEQ72416.1 - 1.1e-17 63.9 0.3 1.7e-17 63.2 0.2 1.3 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 EEQ72416.1 - 0.00013 21.2 0.0 0.00026 20.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF605 PF04652.11 EEQ72416.1 - 0.011 15.1 16.0 0.014 14.8 11.1 1.3 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 EEQ72416.1 - 3.2 7.5 8.4 4.6 7.0 5.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit p450 PF00067.17 EEQ72418.1 - 3.8e-33 114.7 0.0 5e-19 68.1 0.0 2.4 3 0 0 3 3 3 2 Cytochrome P450 OB_RNB PF08206.6 EEQ72418.1 - 0.13 11.8 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain Glutaredoxin PF00462.19 EEQ72419.1 - 2.1e-06 27.5 0.0 2.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Chalcone PF02431.10 EEQ72420.1 - 9.7e-60 201.3 0.0 1.4e-59 200.8 0.0 1.2 1 0 0 1 1 1 1 Chalcone-flavanone isomerase IBR PF01485.16 EEQ72421.1 - 7.2e-07 28.9 23.1 8.8e-05 22.3 7.5 5.1 4 3 0 4 4 4 2 IBR domain WD40 PF00400.27 EEQ72422.1 - 8.9e-40 133.1 30.4 1.9e-08 33.8 0.1 11.6 11 1 0 11 11 11 5 WD domain, G-beta repeat NACHT PF05729.7 EEQ72422.1 - 2.2e-11 43.6 0.2 5e-11 42.5 0.1 1.7 1 0 0 1 1 1 1 NACHT domain eIF2A PF08662.6 EEQ72422.1 - 1.1e-08 34.9 0.1 0.12 12.0 0.0 4.6 3 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EEQ72422.1 - 8.7e-06 25.2 3.0 17 5.2 0.0 6.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat AAA_16 PF13191.1 EEQ72422.1 - 0.00025 21.0 0.5 0.00025 21.0 0.3 2.4 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 EEQ72422.1 - 0.0035 16.2 0.0 0.009 14.9 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain APS_kinase PF01583.15 EEQ72422.1 - 0.01 15.4 0.1 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.1 EEQ72422.1 - 0.013 15.6 1.3 0.048 13.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 EEQ72422.1 - 0.015 15.4 0.2 0.23 11.6 0.0 2.9 3 0 0 3 3 3 0 RNA helicase AAA_19 PF13245.1 EEQ72422.1 - 0.025 14.3 0.1 0.069 12.9 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 EEQ72422.1 - 0.12 11.9 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EEQ72422.1 - 0.2 11.8 1.9 2 8.5 0.0 3.3 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEQ72422.1 - 0.45 11.3 4.9 0.93 10.3 0.4 3.2 2 1 0 2 2 2 0 AAA domain Cg6151-P PF10233.4 EEQ72423.1 - 1.1e-38 131.6 13.7 1.3e-38 131.4 9.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P PRA1 PF03208.14 EEQ72423.1 - 2.2 7.6 13.1 7.9 5.8 9.2 1.8 1 1 0 1 1 1 0 PRA1 family protein NTF2 PF02136.15 EEQ72424.1 - 1.9e-28 99.2 0.1 2.2e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Surp PF01805.15 EEQ72425.1 - 2.3e-17 62.3 0.0 3.8e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Surp module DUF1628 PF07790.6 EEQ72427.1 - 0.055 14.2 1.0 0.14 12.9 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) DUF3084 PF11283.3 EEQ72427.1 - 0.43 10.4 3.9 0.75 9.6 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3084) DUF3169 PF11368.3 EEQ72427.1 - 0.54 9.4 1.8 0.8 8.8 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Gly-zipper_Omp PF13488.1 EEQ72427.1 - 1.5 8.4 13.3 3.2 7.4 9.2 1.5 1 0 0 1 1 1 0 Glycine zipper Rick_17kDa_Anti PF05433.10 EEQ72427.1 - 2 8.1 15.2 3.5 7.3 10.6 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.1 EEQ72427.1 - 2.5 7.6 13.7 5.2 6.6 9.5 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper PQ-loop PF04193.9 EEQ72430.1 - 4.2e-21 74.2 22.6 6.9e-12 44.7 1.0 3.5 3 1 1 4 4 4 2 PQ loop repeat AzlD PF05437.7 EEQ72430.1 - 0.036 13.9 6.0 0.11 12.4 4.2 1.8 1 0 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) DUF485 PF04341.7 EEQ72430.1 - 6.1 6.6 10.7 8.8 6.1 0.9 2.9 3 1 0 3 3 3 0 Protein of unknown function, DUF485 Ish1 PF10281.4 EEQ72431.1 - 2.6e-76 251.2 13.2 1.9e-15 56.5 0.1 7.5 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.2 EEQ72431.1 - 3.1e-06 26.6 0.6 0.23 11.0 0.0 4.0 4 0 0 4 4 4 2 HeH/LEM domain SAP PF02037.22 EEQ72431.1 - 4.9e-06 25.9 0.0 2.6 7.6 0.0 5.5 5 1 0 5 5 5 2 SAP domain Slx4 PF09494.5 EEQ72431.1 - 2.5e-05 23.9 0.1 10 5.9 0.0 4.6 4 0 0 4 4 4 2 Slx4 endonuclease APC2 PF08672.6 EEQ72431.1 - 0.0014 18.7 0.7 33 4.8 0.0 4.7 5 0 0 5 5 5 0 Anaphase promoting complex (APC) subunit 2 ECM11 PF15463.1 EEQ72431.1 - 0.0037 17.5 0.6 0.013 15.8 0.4 1.9 1 0 0 1 1 1 1 Extracellular mutant protein 11 Cyt-b5 PF00173.23 EEQ72432.1 - 6e-15 54.8 0.0 7.9e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SnAC PF14619.1 EEQ72433.1 - 0.0015 18.6 0.8 1.5 9.0 0.0 2.5 2 0 0 2 2 2 2 Snf2-ATP coupling, chromatin remodelling complex TMA7 PF09072.5 EEQ72434.1 - 4.9e-27 94.1 21.8 5.4e-27 94.0 15.1 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 PKK PF12474.3 EEQ72434.1 - 0.11 12.1 2.5 0.13 11.9 1.8 1.1 1 0 0 1 1 1 0 Polo kinase kinase Pkinase PF00069.20 EEQ72435.1 - 3.1e-52 177.2 0.0 5.4e-52 176.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ72435.1 - 1.3e-22 80.1 0.0 3.3e-22 78.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EEQ72435.1 - 0.027 13.2 0.1 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrhK PF14145.1 EEQ72436.1 - 7.5e-06 25.5 19.7 0.029 14.0 3.9 5.0 4 1 0 4 4 4 3 YrhK-like protein Pkinase PF00069.20 EEQ72439.1 - 4.3e-59 199.7 0.0 5.6e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ72439.1 - 2.3e-33 115.3 0.0 2.9e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ72439.1 - 0.00081 18.4 0.0 0.0017 17.3 0.0 1.7 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EEQ72439.1 - 0.0092 15.7 0.0 0.02 14.6 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ72439.1 - 0.036 13.1 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EEQ72439.1 - 0.091 12.3 0.1 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 EEQ72439.1 - 0.13 11.0 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Gag_spuma PF03276.9 EEQ72439.1 - 1.2 7.3 5.6 1.7 6.8 3.9 1.1 1 0 0 1 1 1 0 Spumavirus gag protein adh_short PF00106.20 EEQ72440.1 - 4.6e-33 114.4 2.7 4.6e-33 114.4 1.8 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ72440.1 - 9.2e-25 87.7 0.6 2.6e-24 86.2 0.5 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ72440.1 - 5.9e-16 58.6 1.0 8e-16 58.2 0.7 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EEQ72440.1 - 0.0084 15.7 2.0 0.018 14.7 1.4 1.5 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EEQ72440.1 - 0.08 12.9 0.4 0.18 11.8 0.3 1.7 1 0 0 1 1 1 0 TrkA-N domain AdoHcyase_NAD PF00670.16 EEQ72440.1 - 0.11 12.2 2.8 0.23 11.3 1.9 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain HlyIII PF03006.15 EEQ72441.1 - 9.7e-60 201.7 19.6 1.2e-59 201.4 13.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related 60KD_IMP PF02096.15 EEQ72441.1 - 0.13 11.9 0.8 0.2 11.2 0.6 1.6 1 1 0 1 1 1 0 60Kd inner membrane protein DUF3325 PF11804.3 EEQ72441.1 - 0.52 10.2 5.4 0.067 13.1 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) SAC3_GANP PF03399.11 EEQ72442.1 - 1.8e-07 30.9 0.1 3.1e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EEQ72442.1 - 0.017 14.8 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 TPR_19 PF14559.1 EEQ72443.1 - 3.9e-06 27.0 2.3 0.02 15.2 0.4 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ72443.1 - 0.0023 17.8 0.8 1 9.3 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ72443.1 - 0.011 16.3 1.5 2.1 9.1 0.1 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 EEQ72443.1 - 0.034 14.0 0.5 0.096 12.6 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ72443.1 - 0.15 12.0 2.2 15 5.8 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Glycos_transf_2 PF00535.21 EEQ72444.1 - 5.1e-34 117.3 0.0 6.2e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EEQ72444.1 - 3.7e-13 49.8 0.0 5.7e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EEQ72444.1 - 3.5e-08 32.8 0.0 5.1e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EEQ72444.1 - 4.2e-05 22.9 0.0 6.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF4471 PF14740.1 EEQ72444.1 - 0.051 12.7 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) DUF4295 PF14128.1 EEQ72444.1 - 0.16 11.6 0.3 0.3 10.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4295) DUF1749 PF08538.5 EEQ72445.1 - 1.1e-99 333.1 0.0 1.2e-99 333.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EEQ72445.1 - 5.4e-06 26.4 0.0 6.8e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ72445.1 - 0.0014 18.4 0.0 0.0019 17.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family WD40 PF00400.27 EEQ72446.1 - 0.0005 19.8 10.6 3.6 7.6 0.1 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat Vps35 PF03635.12 EEQ72449.1 - 0 1023.3 0.3 0 1023.1 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 NST1 PF13945.1 EEQ72450.1 - 1.9e-80 269.4 5.1 1.9e-80 269.4 3.6 4.9 3 1 1 4 4 4 1 Salt tolerance down-regulator Ras PF00071.17 EEQ72451.1 - 2.3e-46 157.1 0.0 2.7e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ72451.1 - 5.1e-16 59.2 0.0 7.7e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ72451.1 - 4.3e-07 29.3 0.0 5.7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EEQ72451.1 - 0.0015 17.7 0.0 0.0028 16.9 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EEQ72451.1 - 0.012 15.1 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 EEQ72451.1 - 0.019 14.1 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MRP-L28 PF09812.4 EEQ72452.1 - 7.1e-07 29.1 0.0 9.6e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 RINGv PF12906.2 EEQ72453.1 - 2.3e-05 24.3 6.0 4.2e-05 23.5 4.2 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 EEQ72453.1 - 0.00027 20.8 2.9 0.00059 19.7 2.0 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 EEQ72453.1 - 0.0023 17.7 4.8 0.0038 17.0 3.3 1.4 1 0 0 1 1 1 1 Ring finger domain TPP_enzyme_N PF02776.13 EEQ72454.1 - 6.8e-57 191.6 0.1 1.5e-56 190.6 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EEQ72454.1 - 5.2e-48 162.5 0.1 4.6e-46 156.1 0.0 2.8 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EEQ72454.1 - 9.8e-38 129.0 0.3 2.2e-37 127.8 0.1 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 EEQ72454.1 - 0.025 14.0 0.1 0.051 13.0 0.1 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg ketoacyl-synt PF00109.21 EEQ72455.1 - 7.5e-70 235.3 0.0 1.3e-69 234.4 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EEQ72455.1 - 9.4e-61 204.6 0.1 2.2e-60 203.4 0.1 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EEQ72455.1 - 5.9e-49 166.8 0.0 1e-48 166.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EEQ72455.1 - 7.9e-48 162.5 0.1 1.7e-47 161.4 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Acyl_transf_1 PF00698.16 EEQ72455.1 - 1e-46 159.7 0.1 2.3e-46 158.6 0.1 1.5 1 1 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EEQ72455.1 - 1.7e-37 127.8 0.1 4e-37 126.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EEQ72455.1 - 9e-20 70.5 0.0 3.2e-19 68.7 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EEQ72455.1 - 1.9e-18 66.7 0.0 5.7e-18 65.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ72455.1 - 9.9e-16 57.8 0.0 2.2e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ72455.1 - 1.7e-14 53.6 0.0 5.6e-14 51.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ72455.1 - 6.4e-10 39.6 0.0 1.2e-08 35.5 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ72455.1 - 1.3e-09 38.3 0.0 5.9e-09 36.3 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EEQ72455.1 - 6.9e-08 33.4 0.0 8.7e-07 29.8 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEQ72455.1 - 1.2e-06 28.2 0.5 3.4e-06 26.7 0.4 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 EEQ72455.1 - 7.2e-05 21.8 0.1 0.00015 20.8 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_25 PF13649.1 EEQ72455.1 - 0.00023 21.4 0.0 0.001 19.3 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ72455.1 - 0.00085 18.4 0.0 0.0021 17.2 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 EEQ72455.1 - 0.009 16.2 0.0 0.023 14.9 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ACP_syn_III PF08545.5 EEQ72455.1 - 0.01 15.4 0.2 0.024 14.2 0.1 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NAD_binding_10 PF13460.1 EEQ72455.1 - 0.032 14.2 0.0 19 5.1 0.0 3.3 3 0 0 3 3 3 0 NADH(P)-binding Methyltransf_26 PF13659.1 EEQ72455.1 - 0.038 14.0 0.0 0.2 11.6 0.0 2.3 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EEQ72455.1 - 0.047 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_28 PF02636.12 EEQ72455.1 - 0.061 12.7 0.0 0.22 10.9 0.0 1.9 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase SOUL PF04832.7 EEQ72455.1 - 0.24 10.9 0.0 0.54 9.7 0.0 1.6 1 0 0 1 1 1 0 SOUL heme-binding protein Methyltransf_23 PF13489.1 EEQ72457.1 - 6e-24 84.5 0.1 1.2e-23 83.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ72457.1 - 1.9e-09 38.1 0.1 1.8e-08 34.9 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ72457.1 - 3.6e-08 33.1 0.0 1.8e-07 30.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ72457.1 - 3.8e-06 27.2 0.0 3e-05 24.4 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ72457.1 - 3.3e-05 24.2 0.0 6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ72457.1 - 3.5e-05 24.0 0.0 7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEQ72457.1 - 0.0011 18.0 0.0 0.0054 15.8 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 EEQ72457.1 - 0.0035 16.7 0.0 0.01 15.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.14 EEQ72457.1 - 0.014 14.9 0.1 0.34 10.4 0.1 2.2 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EEQ72457.1 - 0.019 14.0 0.0 0.19 10.8 0.0 2.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EEQ72457.1 - 0.056 12.5 0.1 1.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase GalKase_gal_bdg PF10509.4 EEQ72458.1 - 2.4e-19 68.3 0.0 4.2e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 EEQ72458.1 - 1.9e-13 50.3 0.0 4.1e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 EEQ72458.1 - 3.2e-13 49.5 0.7 9.2e-13 48.0 0.5 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain HTH_18 PF12833.2 EEQ72458.1 - 0.081 13.0 0.4 19 5.4 0.0 2.9 2 1 1 3 3 3 0 Helix-turn-helix domain BTB PF00651.26 EEQ72460.1 - 3e-05 23.9 0.0 6.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF4432 PF14486.1 EEQ72461.1 - 0.1 11.1 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) Pkinase PF00069.20 EEQ72462.1 - 1.1e-09 37.8 0.1 4.6e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 EEQ72462.1 - 0.0072 16.0 0.2 0.041 13.6 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EEQ72462.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase AAA PF00004.24 EEQ72463.1 - 4.3e-13 49.6 0.0 1.2e-12 48.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zot PF05707.7 EEQ72463.1 - 0.00093 18.7 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 EEQ72463.1 - 0.0021 18.2 1.9 0.13 12.3 0.7 3.4 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EEQ72463.1 - 0.015 16.1 0.2 0.095 13.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EEQ72463.1 - 0.028 14.7 0.0 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EEQ72463.1 - 0.04 13.3 0.0 0.15 11.4 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein APH PF01636.18 EEQ72466.1 - 1.2e-09 38.2 0.0 4.3e-09 36.4 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ72466.1 - 9.3e-07 28.6 0.0 4.2e-05 23.2 0.0 2.2 1 1 0 1 1 1 1 Choline/ethanolamine kinase INTS5_C PF14838.1 EEQ72467.1 - 0.038 12.2 0.5 0.041 12.1 0.4 1.0 1 0 0 1 1 1 0 Integrator complex subunit 5 C-terminus CDT1 PF08839.6 EEQ72467.1 - 0.065 13.1 0.7 0.074 12.9 0.5 1.0 1 0 0 1 1 1 0 DNA replication factor CDT1 like adh_short PF00106.20 EEQ72468.1 - 2.7e-31 108.7 0.2 4.1e-31 108.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ72468.1 - 3.3e-23 82.6 0.0 4.6e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ72468.1 - 1.5e-12 47.5 0.1 3.1e-12 46.5 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EEQ72468.1 - 1e-05 25.1 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EEQ72468.1 - 0.0033 17.1 0.0 0.0058 16.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EEQ72468.1 - 0.041 12.9 0.0 0.083 11.9 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.10 EEQ72468.1 - 0.073 11.9 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EEQ72468.1 - 0.1 11.4 0.1 0.21 10.4 0.1 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain Ferric_reduct PF01794.14 EEQ72469.1 - 3e-19 69.3 11.2 3e-19 69.3 7.7 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EEQ72469.1 - 2.5e-13 50.2 0.1 2.6e-09 37.1 0.0 2.7 2 1 1 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EEQ72469.1 - 1.7e-11 43.8 0.1 2.6e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 EEQ72469.1 - 0.0085 16.6 0.1 0.08 13.5 0.0 2.5 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain Herpes_UL20 PF04544.7 EEQ72469.1 - 0.053 13.3 0.5 0.14 12.0 0.1 1.8 2 0 0 2 2 2 0 Herpesvirus egress protein UL20 GAT PF03127.9 EEQ72470.1 - 7.6e-13 48.3 0.0 1.8e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 GAT domain VHS PF00790.14 EEQ72470.1 - 0.00063 19.3 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 VHS domain PAT1 PF09770.4 EEQ72470.1 - 1.8 6.7 22.5 2.6 6.1 15.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ADH_zinc_N_2 PF13602.1 EEQ72472.1 - 1.1e-21 78.0 0.0 2.4e-21 76.9 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EEQ72472.1 - 1e-14 54.1 0.4 2.1e-14 53.2 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase IPI_T4 PF11634.3 EEQ72472.1 - 0.049 13.5 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 Nuclease inhibitor from bacteriophage T4 Cation_efflux PF01545.16 EEQ72476.1 - 9.3e-27 93.8 4.8 1.1e-26 93.5 3.3 1.1 1 0 0 1 1 1 1 Cation efflux family Sec61_beta PF03911.11 EEQ72476.1 - 3.5 7.5 6.0 0.92 9.3 0.0 2.8 3 0 0 3 3 3 0 Sec61beta family 2_5_RNA_ligase2 PF13563.1 EEQ72477.1 - 1.8e-28 99.2 0.0 3.3e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PAP_central PF04928.12 EEQ72477.1 - 9.2e-28 96.7 0.0 1.7e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain DUF504 PF04457.7 EEQ72477.1 - 1.1e-13 51.1 0.8 2.9e-13 49.7 0.6 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF504) PAP_RNA-bind PF04926.10 EEQ72477.1 - 1.1e-07 31.4 0.0 2.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EEQ72477.1 - 0.00028 21.1 0.0 0.00066 19.9 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain AKAP7_NLS PF10469.4 EEQ72477.1 - 0.0021 17.8 0.0 0.01 15.5 0.0 2.1 2 0 0 2 2 2 1 AKAP7 2'5' RNA ligase-like domain PAP_assoc PF03828.14 EEQ72477.1 - 0.0038 17.1 0.4 0.012 15.5 0.3 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase Nrap PF03813.9 EEQ72477.1 - 0.035 11.6 0.0 0.051 11.1 0.0 1.1 1 0 0 1 1 1 0 Nrap protein YL1 PF05764.8 EEQ72477.1 - 0.32 10.5 2.3 0.59 9.6 1.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein PSRP-3_Ycf65 PF04839.8 EEQ72479.1 - 0.072 13.1 0.8 9.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) PNP_UDP_1 PF01048.15 EEQ72481.1 - 5.6e-12 45.1 1.7 2.3e-11 43.1 1.2 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily Peptidase_S31 PF05578.7 EEQ72481.1 - 0.12 11.5 0.3 2.8 7.0 0.1 2.2 2 0 0 2 2 2 0 Pestivirus NS3 polyprotein peptidase S31 Aminotran_1_2 PF00155.16 EEQ72482.1 - 1.3e-16 60.5 0.0 8e-16 57.9 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II MFS_1 PF07690.11 EEQ72483.1 - 4.4e-26 91.4 29.9 1.5e-20 73.2 12.9 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily CD34_antigen PF06365.7 EEQ72483.1 - 0.27 10.8 0.0 0.57 9.7 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family Pectate_lyase_3 PF12708.2 EEQ72487.1 - 1.6e-90 303.1 14.2 3.3e-71 240.0 8.3 2.5 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EEQ72487.1 - 4.2e-08 32.5 1.5 0.00039 19.8 0.0 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 EEQ72487.1 - 1.2 8.8 14.9 5 6.8 10.3 2.1 1 1 0 1 1 1 0 Right handed beta helix region MIase PF02426.11 EEQ72488.1 - 0.023 14.4 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Muconolactone delta-isomerase HSP20 PF00011.16 EEQ72489.1 - 2e-09 37.2 1.1 3.2e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 Hsp20/alpha crystallin family Pyr_redox_2 PF07992.9 EEQ72490.1 - 1.1e-26 94.0 0.0 1.4e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEQ72490.1 - 6.5e-09 36.0 0.0 4.8e-08 33.2 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amidase PF01425.16 EEQ72491.1 - 7.6e-86 288.6 0.0 9e-86 288.4 0.0 1.0 1 0 0 1 1 1 1 Amidase PAP_central PF04928.12 EEQ72493.1 - 8.5e-104 345.8 0.0 1.1e-103 345.4 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EEQ72493.1 - 1.5e-50 170.7 0.0 2.7e-50 169.9 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EEQ72493.1 - 3.4e-10 40.0 0.0 7.3e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap PF03813.9 EEQ72493.1 - 0.087 10.3 0.0 0.13 9.7 0.0 1.1 1 0 0 1 1 1 0 Nrap protein Striatin PF08232.7 EEQ72494.1 - 0.034 14.4 0.1 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 Striatin family Flavin_Reduct PF01613.13 EEQ72495.1 - 2.9e-20 72.6 0.1 4.6e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Fungal_trans PF04082.13 EEQ72496.1 - 8.9e-20 70.6 0.6 4.1e-18 65.2 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ72496.1 - 0.00026 20.8 4.4 0.00047 20.0 3.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain La PF05383.12 EEQ72496.1 - 0.023 14.5 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 La domain But2 PF09792.4 EEQ72498.1 - 8.7e-05 22.3 0.0 0.00069 19.3 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Mito_carr PF00153.22 EEQ72499.1 - 4.7e-43 144.8 7.0 1.5e-16 59.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.8 EEQ72499.1 - 0.3 10.6 3.5 0.17 11.4 0.3 2.2 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Alpha-amylase PF00128.19 EEQ72500.1 - 1.1e-35 123.5 0.0 1.8e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EEQ72500.1 - 1.1e-08 33.4 0.0 0.013 13.2 0.0 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 hDGE_amylase PF14701.1 EEQ72500.1 - 0.04 12.8 0.0 0.1 11.4 0.0 1.6 2 0 0 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme DUF1014 PF06244.7 EEQ72501.1 - 1.1e-21 77.3 16.0 1e-20 74.1 11.1 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) DUF966 PF06136.8 EEQ72501.1 - 2.2 7.6 14.7 3.4 7.0 10.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF966) SSFA2_C PF14723.1 EEQ72502.1 - 0.039 13.6 0.4 0.084 12.6 0.3 1.5 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus Zip PF02535.17 EEQ72502.1 - 2.4 7.0 6.9 5.2 5.9 4.8 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter bZIP_C PF12498.3 EEQ72502.1 - 6.5 8.0 7.9 36 5.6 1.1 3.8 3 0 0 3 3 3 0 Basic leucine-zipper C terminal SR-25 PF10500.4 EEQ72503.1 - 0.023 14.1 3.7 0.022 14.2 2.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ctf8 PF09696.5 EEQ72503.1 - 0.031 14.0 1.6 0.045 13.5 1.1 1.2 1 0 0 1 1 1 0 Ctf8 NST1 PF13945.1 EEQ72503.1 - 0.11 12.5 2.7 0.1 12.6 1.9 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator BLVR PF06375.6 EEQ72503.1 - 0.18 11.6 6.7 0.2 11.4 4.7 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Peptidase_C13 PF01650.13 EEQ72504.1 - 3.2e-40 138.0 0.0 4e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family Podoplanin PF05808.6 EEQ72504.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Podoplanin CDC45 PF02724.9 EEQ72505.1 - 5.5e-238 791.0 8.4 1.3e-236 786.4 5.8 2.9 1 1 0 1 1 1 1 CDC45-like protein Hexokinase_1 PF00349.16 EEQ72505.1 - 0.27 10.5 0.0 0.42 9.9 0.0 1.2 1 0 0 1 1 1 0 Hexokinase Nop25 PF09805.4 EEQ72505.1 - 8.5 6.4 24.8 1.6 8.7 10.7 2.5 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) DUF1330 PF07045.6 EEQ72506.1 - 0.00039 20.2 0.0 0.00076 19.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1330) BTB PF00651.26 EEQ72507.1 - 1.6e-06 28.0 0.0 3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Acetyltransf_1 PF00583.19 EEQ72508.1 - 6.6e-08 32.4 0.0 1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ72508.1 - 1.6e-06 28.1 0.0 3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEQ72508.1 - 1.7e-05 24.9 0.0 3.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEQ72508.1 - 0.0037 17.1 0.0 0.0069 16.2 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EEQ72508.1 - 0.1 12.4 0.1 8 6.3 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Autotransporter PF03797.14 EEQ72509.1 - 0.026 13.8 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Autotransporter beta-domain VWA_2 PF13519.1 EEQ72512.1 - 1.4e-08 35.0 0.0 3e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EEQ72512.1 - 3.9e-06 26.8 0.0 5.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 EEQ72512.1 - 2.8e-05 23.8 0.0 0.046 13.4 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain Apc4 PF12896.2 EEQ72514.1 - 2.4e-68 229.5 0.3 3.5e-68 229.0 0.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 EEQ72514.1 - 8.6e-14 50.7 0.0 2.1e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 EEQ72514.1 - 0.01 15.6 0.6 0.13 12.1 0.0 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat Ammonium_transp PF00909.16 EEQ72514.1 - 0.22 9.9 0.1 0.34 9.3 0.0 1.2 1 0 0 1 1 1 0 Ammonium Transporter Family FhuF PF06276.7 EEQ72515.1 - 0.1 12.5 0.3 0.23 11.4 0.2 1.6 1 1 1 2 2 2 0 Ferric iron reductase FhuF-like transporter HEAT PF02985.17 EEQ72516.1 - 4e-18 63.7 5.8 0.00037 20.3 0.0 9.7 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.1 EEQ72516.1 - 2.3e-13 50.2 10.9 1.7e-05 25.0 0.0 6.3 2 2 4 6 6 6 4 HEAT repeats HEAT_EZ PF13513.1 EEQ72516.1 - 2.9e-10 40.3 13.9 5.1e-06 26.8 0.0 8.1 7 3 3 10 10 10 3 HEAT-like repeat IBN_N PF03810.14 EEQ72516.1 - 7.8e-10 38.5 0.8 3.2e-07 30.1 0.0 3.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.3 EEQ72516.1 - 4.1e-06 26.3 0.4 0.11 11.7 0.0 4.6 4 1 2 6 6 6 2 CLASP N terminal Arm PF00514.18 EEQ72516.1 - 7.8e-06 25.5 2.6 2.4 8.0 0.0 5.6 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 EEQ72516.1 - 0.00047 20.3 0.1 2.7 8.7 0.0 4.8 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat DUF3535 PF12054.3 EEQ72516.1 - 0.00077 18.2 1.2 0.0031 16.1 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) Proteasom_PSMB PF10508.4 EEQ72516.1 - 0.011 14.0 0.1 2.8 6.0 0.0 2.9 1 1 1 2 2 2 0 Proteasome non-ATPase 26S subunit Ribosomal_S8 PF00410.14 EEQ72517.1 - 3e-24 85.3 0.0 4.2e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 His_Phos_1 PF00300.17 EEQ72518.1 - 5.6e-16 59.0 0.0 7.9e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PINIT PF14324.1 EEQ72518.1 - 0.055 13.5 0.1 0.094 12.7 0.0 1.3 1 0 0 1 1 1 0 PINIT domain ubiquitin PF00240.18 EEQ72520.1 - 0.0015 17.8 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family PS_Dcarbxylase PF02666.10 EEQ72521.1 - 7.4e-81 270.2 0.0 2e-80 268.8 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl PF00364.17 EEQ72521.1 - 0.098 12.3 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 Biotin-requiring enzyme E1-E2_ATPase PF00122.15 EEQ72522.1 - 1.9e-63 213.5 3.2 2.9e-63 212.9 2.2 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EEQ72522.1 - 1.5e-30 107.2 0.1 2e-25 90.5 0.1 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EEQ72522.1 - 2.8e-27 95.4 6.9 2.8e-27 95.4 4.8 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 EEQ72522.1 - 4.8e-17 61.6 0.0 1e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EEQ72522.1 - 1.7e-14 54.4 0.0 3.8e-14 53.2 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEQ72522.1 - 1.6e-12 46.7 0.0 3.8e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EEQ72522.1 - 3.8e-05 23.3 0.1 0.00074 19.1 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CDP-OH_P_transf PF01066.16 EEQ72523.1 - 6.4e-19 68.1 3.4 6.4e-19 68.1 2.3 1.6 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase APC10 PF03256.11 EEQ72524.1 - 1.5e-40 138.8 0.0 3e-40 137.9 0.0 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Cytotoxic PF09000.5 EEQ72524.1 - 0.0048 16.8 0.8 0.011 15.6 0.5 1.6 1 0 0 1 1 1 1 Cytotoxic GEMIN8 PF15348.1 EEQ72524.1 - 0.12 12.4 0.0 0.12 12.4 0.0 2.3 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Nop14 PF04147.7 EEQ72524.1 - 1.5 6.6 38.9 0.13 10.1 15.7 2.0 2 0 0 2 2 2 0 Nop14-like family SDA1 PF05285.7 EEQ72524.1 - 3.5 6.8 36.0 3.8 6.7 16.2 2.1 2 0 0 2 2 2 0 SDA1 Daxx PF03344.10 EEQ72524.1 - 4.3 5.6 35.6 1.5 7.2 2.7 2.1 2 0 0 2 2 2 0 Daxx Family Iso_dh PF00180.15 EEQ72525.1 - 1.2e-129 432.2 0.0 1.4e-129 432.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PP2C PF00481.16 EEQ72526.1 - 7.9e-33 113.9 0.0 1.7e-27 96.4 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EEQ72526.1 - 0.00011 21.6 0.1 0.00037 19.9 0.0 1.8 2 0 0 2 2 2 1 Protein phosphatase 2C RRM_1 PF00076.17 EEQ72528.1 - 3.6e-40 135.4 0.4 8.7e-19 66.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ72528.1 - 5.2e-32 109.6 0.1 3e-17 62.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EEQ72528.1 - 9.2e-31 105.9 0.1 2.5e-30 104.5 0.0 1.8 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 EEQ72528.1 - 1.1e-21 76.3 0.0 5.7e-09 35.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 EEQ72528.1 - 0.026 13.0 24.9 0.086 11.3 17.6 1.6 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 RRM_3 PF08777.6 EEQ72528.1 - 0.042 13.6 0.0 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 RNA binding motif Cyt-b5 PF00173.23 EEQ72529.1 - 1.6e-19 69.4 0.4 5e-18 64.6 0.1 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EEQ72529.1 - 2.5e-10 40.7 18.3 4.7e-10 39.8 11.2 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 EEQ72529.1 - 0.073 13.0 0.4 0.15 12.0 0.2 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region COX14 PF14880.1 EEQ72529.1 - 1.1 8.9 3.4 2.2 7.9 0.4 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c assembly OMPdecase PF00215.19 EEQ72531.1 - 3.8e-07 29.7 0.0 0.00014 21.3 0.0 2.4 2 0 0 2 2 2 2 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF2420 PF10336.4 EEQ72533.1 - 2.4e-14 52.9 0.0 5e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.16 EEQ72534.1 - 1.1e-18 67.2 0.1 1.6e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EEQ72534.1 - 1.5e-07 31.1 0.2 2.7e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.6 EEQ72534.1 - 0.0048 17.0 0.3 0.0094 16.0 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) Mg_trans_NIPA PF05653.9 EEQ72535.1 - 3.5e-93 311.8 11.3 5e-93 311.3 7.8 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EEQ72535.1 - 0.00012 22.2 17.8 0.00014 22.0 0.5 3.5 2 1 1 3 3 3 2 Multidrug resistance efflux transporter EamA PF00892.15 EEQ72535.1 - 0.00017 21.6 7.7 0.00017 21.6 5.3 3.1 2 1 0 3 3 3 2 EamA-like transporter family LAB_N PF07578.6 EEQ72535.1 - 0.04 13.8 0.4 0.48 10.3 0.2 2.4 2 0 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain DUF2937 PF11157.3 EEQ72535.1 - 0.14 11.4 2.6 0.1 11.9 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) FSH1 PF03959.8 EEQ72536.1 - 1.6e-13 50.6 0.1 6.2e-10 38.8 0.0 2.2 1 1 1 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EEQ72536.1 - 0.073 12.5 0.3 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Acyl_transf_1 PF00698.16 EEQ72537.1 - 1.1e-30 107.0 0.0 7.8e-28 97.7 0.0 2.2 2 0 0 2 2 2 2 Acyl transferase domain Syja_N PF02383.13 EEQ72538.1 - 3.7e-95 318.3 0.0 5.7e-95 317.7 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 EEQ72538.1 - 2.1e-36 123.7 0.0 3.8e-36 122.9 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase TrfA PF07042.6 EEQ72538.1 - 0.032 13.0 0.1 0.056 12.2 0.0 1.3 1 0 0 1 1 1 0 TrfA protein HEAT_2 PF13646.1 EEQ72539.1 - 3.8e-30 103.9 0.4 5.4e-09 36.2 0.0 8.1 3 3 5 8 8 8 7 HEAT repeats HEAT PF02985.17 EEQ72539.1 - 2.7e-29 98.5 21.2 2.4e-05 24.0 0.0 11.2 13 0 0 13 13 12 7 HEAT repeat HEAT_EZ PF13513.1 EEQ72539.1 - 8.9e-29 99.2 13.3 1.2e-13 51.0 0.0 11.4 11 2 3 14 14 13 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EEQ72539.1 - 8.4e-12 45.3 0.0 0.019 15.3 0.0 6.5 5 3 3 8 8 8 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EEQ72539.1 - 1.5e-11 44.4 0.2 0.00017 21.5 0.0 5.2 5 2 0 6 6 6 3 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.3 EEQ72539.1 - 5.6e-11 41.8 3.3 0.013 14.2 0.1 5.5 7 0 0 7 7 7 3 RNAPII transcription regulator C-terminal Adaptin_N PF01602.15 EEQ72539.1 - 1.5e-09 36.7 1.2 0.0038 15.6 0.2 4.1 2 2 1 3 3 3 2 Adaptin N terminal region Arm PF00514.18 EEQ72539.1 - 8.5e-07 28.5 2.9 0.31 10.9 0.0 6.1 6 0 0 6 6 5 1 Armadillo/beta-catenin-like repeat Xpo1 PF08389.7 EEQ72539.1 - 2.6e-06 27.4 0.0 0.001 19.0 0.0 4.1 3 1 0 3 3 3 1 Exportin 1-like protein CLASP_N PF12348.3 EEQ72539.1 - 9.2e-06 25.1 0.4 3.3 7.0 0.0 7.0 5 3 2 7 7 7 1 CLASP N terminal HEAT_PBS PF03130.11 EEQ72539.1 - 0.00021 21.4 2.0 0.52 10.9 0.0 4.8 5 0 0 5 5 3 1 PBS lyase HEAT-like repeat RIX1 PF08167.7 EEQ72539.1 - 0.00061 19.4 1.1 5.7 6.5 0.0 4.6 3 2 2 5 5 5 1 rRNA processing/ribosome biogenesis Cohesin_HEAT PF12765.2 EEQ72539.1 - 0.0026 17.6 0.1 67 3.5 0.1 5.8 6 0 0 6 6 6 0 HEAT repeat associated with sister chromatid cohesion Nipped-B_C PF12830.2 EEQ72539.1 - 0.017 14.7 0.1 10 5.7 0.0 3.8 3 1 0 4 4 4 0 Sister chromatid cohesion C-terminus IBN_N PF03810.14 EEQ72539.1 - 0.02 14.8 0.1 0.68 9.8 0.0 3.5 2 1 0 2 2 1 0 Importin-beta N-terminal domain DUF3437 PF11919.3 EEQ72539.1 - 0.03 14.0 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) UPF0253 PF06786.7 EEQ72539.1 - 0.12 12.5 0.3 1.2 9.2 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0253) Fungal_trans_2 PF11951.3 EEQ72544.1 - 1.6e-09 36.8 2.0 2.6e-09 36.1 1.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ72544.1 - 7.8e-09 35.2 12.8 1.5e-08 34.3 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3865 PF12981.2 EEQ72544.1 - 0.24 11.1 1.0 0.7 9.6 0.5 1.8 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3865) Peptidase_C12 PF01088.16 EEQ72546.1 - 1.7e-70 236.5 0.0 2.4e-70 236.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Choline_kinase PF01633.15 EEQ72547.1 - 2.1e-62 210.4 0.0 3.8e-62 209.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 EEQ72547.1 - 4.2e-14 51.7 0.0 8.4e-14 50.7 0.0 1.5 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 EEQ72547.1 - 2.7e-09 37.1 0.0 2.7e-09 37.1 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Mem_trans PF03547.13 EEQ72549.1 - 3.5e-54 183.5 0.7 4.5e-54 183.2 0.5 1.1 1 0 0 1 1 1 1 Membrane transport protein APH PF01636.18 EEQ72550.1 - 1.4e-07 31.4 0.0 3.5e-06 26.9 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ72550.1 - 0.055 12.5 0.0 0.081 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EEQ72550.1 - 0.15 11.5 0.1 0.25 10.8 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 EEQ72551.1 - 0.00071 18.8 0.0 0.0009 18.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Bromodomain PF00439.20 EEQ72552.1 - 1e-24 86.2 0.1 2.1e-24 85.2 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EEQ72552.1 - 1.6e-08 34.5 0.4 3.9e-08 33.3 0.3 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEQ72552.1 - 3.5e-08 33.3 0.1 7.8e-08 32.2 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Pkinase PF00069.20 EEQ72553.1 - 1.7e-49 168.2 0.0 6e-47 159.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ72553.1 - 5e-31 107.7 0.0 2.7e-30 105.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ72553.1 - 0.00045 19.2 0.0 0.00069 18.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EEQ72553.1 - 0.0013 17.5 0.1 0.0023 16.8 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EEQ72553.1 - 0.043 12.6 0.0 0.063 12.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pyr_redox_2 PF07992.9 EEQ72554.1 - 4.5e-37 127.8 0.2 7.1e-37 127.2 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EEQ72554.1 - 4.7e-32 110.2 1.1 6e-32 109.9 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EEQ72554.1 - 7.8e-16 58.2 0.1 7.8e-16 58.2 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEQ72554.1 - 5.1e-05 23.4 0.0 0.00029 20.9 0.0 2.2 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEQ72554.1 - 0.0074 15.2 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 EEQ72554.1 - 0.036 13.1 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEQ72554.1 - 0.045 12.5 3.2 3.8 6.2 0.5 2.9 3 0 0 3 3 3 0 FAD binding domain 3HCDH_N PF02737.13 EEQ72554.1 - 0.057 13.0 0.1 0.17 11.4 0.0 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EEQ72554.1 - 0.22 10.3 1.3 1.4 7.7 0.2 2.5 4 0 0 4 4 4 0 Glucose inhibited division protein A DAO PF01266.19 EEQ72554.1 - 8.8 5.1 6.9 0.28 10.0 0.1 1.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase ECH PF00378.15 EEQ72555.1 - 3.2e-33 114.8 0.0 5.3e-33 114.1 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Fungal_trans PF04082.13 EEQ72556.1 - 1e-13 50.7 0.1 2.3e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain tRNA-synt_2b PF00587.20 EEQ72558.1 - 4.8e-50 169.5 0.0 6.7e-50 169.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEQ72558.1 - 7e-07 29.0 0.0 1.9e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain Fungal_trans PF04082.13 EEQ72559.1 - 2.1e-27 95.6 0.5 3.4e-27 94.9 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_2 PF04909.9 EEQ72560.1 - 7.8e-20 71.5 0.1 9.2e-20 71.3 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase Glyco_transf_28 PF03033.15 EEQ72562.1 - 1.6e-20 73.2 0.0 6.4e-20 71.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EEQ72562.1 - 2.8e-06 26.1 0.0 4.8e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EEQ72562.1 - 0.00011 21.9 0.1 0.00085 19.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.6 EEQ72562.1 - 0.005 16.9 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain Glyco_hydro_31 PF01055.21 EEQ72565.1 - 1.5e-182 607.3 1.3 1.8e-182 607.0 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EEQ72565.1 - 3e-10 39.8 0.9 8.6e-10 38.3 0.6 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like PTR2 PF00854.16 EEQ72566.1 - 4.8e-37 127.6 14.5 4.1e-20 71.9 1.9 2.4 3 0 0 3 3 3 2 POT family Ifi-6-16 PF06140.8 EEQ72568.1 - 0.00046 19.9 24.0 0.00046 19.9 16.7 1.7 1 1 0 1 1 1 1 Interferon-induced 6-16 family VSP PF03302.8 EEQ72571.1 - 0.015 13.9 0.4 0.022 13.3 0.3 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein T2SM PF04612.7 EEQ72571.1 - 0.1 12.3 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M TMEM51 PF15345.1 EEQ72571.1 - 0.12 12.1 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DUF3043 PF11241.3 EEQ72571.1 - 0.3 10.6 0.8 0.61 9.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) MFS_1 PF07690.11 EEQ72572.1 - 2.1e-21 76.0 39.1 5.4e-15 54.9 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ72572.1 - 4.4e-16 58.5 21.5 6.6e-16 57.9 14.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Hexapep PF00132.19 EEQ72575.1 - 4.5e-10 38.5 1.3 7.4e-05 22.0 0.3 2.8 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EEQ72575.1 - 0.0074 16.3 0.0 0.017 15.2 0.0 1.7 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 EEQ72575.1 - 0.066 12.4 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase Peroxin-22 PF12827.2 EEQ72576.1 - 0.071 12.8 0.0 0.38 10.4 0.0 1.9 2 0 0 2 2 2 0 Peroxisomal biogenesis protein family Spt20 PF12090.3 EEQ72577.1 - 1.5e-47 161.3 0.0 1.5e-47 161.3 0.0 4.1 2 1 0 2 2 2 1 Spt20 family 2OG-FeII_Oxy PF03171.15 EEQ72578.1 - 1.5e-16 60.4 0.0 2.2e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BCNT PF07572.7 EEQ72579.1 - 2.2e-28 98.0 0.5 2.2e-28 98.0 0.3 1.8 2 0 0 2 2 2 1 Bucentaur or craniofacial development FA_desaturase PF00487.19 EEQ72580.1 - 0.066 12.6 2.9 0.16 11.3 2.0 1.7 1 1 0 1 1 1 0 Fatty acid desaturase DUF202 PF02656.10 EEQ72580.1 - 3.8 7.7 8.7 1.3e+02 2.8 6.0 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Mis12 PF05859.7 EEQ72581.1 - 1.7e-44 151.1 0.0 2.6e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein DDE_5 PF13546.1 EEQ72581.1 - 0.084 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease Type_III_YscG PF09477.5 EEQ72582.1 - 0.012 15.6 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) Cu_bind_like PF02298.12 EEQ72582.1 - 0.18 11.6 0.2 0.9 9.3 0.1 1.9 1 1 0 1 1 1 0 Plastocyanin-like domain CENP-X PF09415.5 EEQ72583.1 - 4.2e-24 84.1 0.0 6.9e-24 83.4 0.0 1.4 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.18 EEQ72583.1 - 0.0046 16.9 0.0 0.0086 16.1 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF605 PF04652.11 EEQ72583.1 - 0.85 8.9 15.7 1.1 8.6 10.9 1.3 1 0 0 1 1 1 0 Vta1 like Hamartin PF04388.7 EEQ72583.1 - 1.7 7.2 9.3 1.8 7.1 6.5 1.1 1 0 0 1 1 1 0 Hamartin protein Pneumo_att_G PF05539.6 EEQ72583.1 - 2.9 7.1 12.6 3.8 6.7 8.7 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Dicty_REP PF05086.7 EEQ72583.1 - 3.9 5.1 5.5 4.5 4.9 3.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Macro PF01661.16 EEQ72584.1 - 7e-12 45.2 0.0 7.7e-07 29.0 0.0 2.3 2 1 0 2 2 2 2 Macro domain API5 PF05918.6 EEQ72584.1 - 2.2 6.6 4.1 3 6.2 2.8 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) MIF PF01187.13 EEQ72585.1 - 5.5e-09 36.1 0.1 8.8e-09 35.4 0.1 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) NOD PF06816.8 EEQ72585.1 - 0.071 12.2 0.1 0.16 11.0 0.1 1.5 1 0 0 1 1 1 0 NOTCH protein Dus PF01207.12 EEQ72586.1 - 1.1e-56 191.9 0.0 2.2e-56 190.9 0.0 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 EEQ72586.1 - 0.006 15.5 0.0 0.0099 14.8 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase EGL-1 PF11430.3 EEQ72588.1 - 0.05 13.2 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Programmed cell death activator EGL-1 bZIP_1 PF00170.16 EEQ72589.1 - 1.4e-09 37.8 10.6 3.8e-09 36.3 7.4 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEQ72589.1 - 0.00028 20.6 9.8 0.00028 20.6 6.8 2.7 2 0 0 2 2 2 1 Basic region leucine zipper Med15 PF09606.5 EEQ72589.1 - 0.0027 15.9 56.8 0.0038 15.5 39.4 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.8 EEQ72589.1 - 0.061 12.1 33.0 0.0089 14.9 17.3 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Lactamase_B_2 PF12706.2 EEQ72590.1 - 7.9e-34 116.8 0.1 1.4e-33 116.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EEQ72590.1 - 4.8e-23 80.3 0.0 3.7e-22 77.5 0.0 2.3 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 EEQ72590.1 - 6.2e-11 42.3 0.0 1.5e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Aldo_ket_red PF00248.16 EEQ72591.1 - 1.4e-38 132.3 0.0 9.6e-37 126.3 0.0 2.4 1 1 0 1 1 1 1 Aldo/keto reductase family Methyltransf_23 PF13489.1 EEQ72593.1 - 2.3e-21 76.2 0.0 3.3e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ72593.1 - 1.9e-13 50.6 0.0 3.8e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ72593.1 - 1.2e-11 44.4 0.0 1.3e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ72593.1 - 1.7e-10 41.4 0.0 3.4e-09 37.2 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ72593.1 - 1.7e-08 34.8 0.0 2.2e-07 31.2 0.0 2.5 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ72593.1 - 1.2e-05 25.6 0.0 4.5e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ72593.1 - 4.2e-05 23.5 0.0 0.00017 21.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ72593.1 - 0.0002 20.5 0.0 0.0017 17.5 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EEQ72593.1 - 0.0023 17.0 0.0 0.014 14.4 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_16 PF10294.4 EEQ72593.1 - 0.0037 16.7 0.0 0.007 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EEQ72593.1 - 0.017 14.5 0.0 0.057 12.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.8 EEQ72593.1 - 0.021 13.9 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 EEQ72593.1 - 0.077 12.0 0.0 0.38 9.8 0.0 2.1 2 1 0 2 2 2 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EEQ72593.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.14 EEQ72593.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.7 EEQ72593.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) His_Phos_2 PF00328.17 EEQ72594.1 - 6e-19 68.5 0.0 5.1e-18 65.5 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Gtr1_RagA PF04670.7 EEQ72595.1 - 1.5e-51 174.7 0.1 2.4e-51 174.1 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 EEQ72595.1 - 0.03 13.8 0.1 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Arf PF00025.16 EEQ72595.1 - 0.11 11.6 0.1 0.23 10.6 0.0 1.6 1 1 0 1 1 1 0 ADP-ribosylation factor family Cyt-b5 PF00173.23 EEQ72596.1 - 1.3e-05 24.8 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_S25 PF03297.10 EEQ72597.1 - 8.5e-40 135.0 4.6 9.4e-40 134.9 3.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.7 EEQ72597.1 - 0.027 14.0 0.1 0.037 13.5 0.1 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain TrmB PF01978.14 EEQ72597.1 - 0.033 13.9 0.3 0.042 13.5 0.2 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB FeoC PF09012.5 EEQ72597.1 - 0.043 13.5 0.3 0.11 12.2 0.0 1.7 1 1 1 2 2 2 0 FeoC like transcriptional regulator MarR_2 PF12802.2 EEQ72597.1 - 0.059 13.0 0.1 0.081 12.6 0.1 1.3 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.1 EEQ72597.1 - 0.09 12.1 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding GntR PF00392.16 EEQ72597.1 - 0.1 12.0 0.1 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family WD40 PF00400.27 EEQ72598.1 - 1.3e-07 31.2 0.2 0.29 11.0 0.0 5.4 5 1 0 5 5 5 2 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EEQ72598.1 - 0.00019 20.8 0.0 0.66 9.5 0.0 4.0 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 EEQ72598.1 - 0.0003 18.7 0.1 0.0011 16.8 0.0 1.9 2 0 0 2 2 2 1 IKI3 family eIF2A PF08662.6 EEQ72598.1 - 0.035 13.8 0.0 0.11 12.1 0.0 1.9 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Mob_synth_C PF06463.8 EEQ72600.1 - 8.5e-36 122.4 0.0 3.4e-35 120.5 0.0 1.9 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EEQ72600.1 - 3e-21 76.2 0.0 5e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily MoaC PF01967.16 EEQ72600.1 - 1.7e-20 73.0 0.1 2.9e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 MoaC family Fer4_12 PF13353.1 EEQ72600.1 - 0.00019 21.5 0.0 0.00033 20.8 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EEQ72600.1 - 0.0007 19.6 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Noc2 PF03715.8 EEQ72601.1 - 2.2e-122 407.6 0.0 4.6e-122 406.5 0.0 1.6 1 0 0 1 1 1 1 Noc2p family VPS28 PF03997.7 EEQ72602.1 - 4.5e-61 205.7 0.1 5.3e-61 205.5 0.1 1.1 1 0 0 1 1 1 1 VPS28 protein Imm3 PF14425.1 EEQ72602.1 - 0.16 11.9 1.3 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 Immunity protein Imm3 GvpG PF05120.7 EEQ72602.1 - 0.72 9.6 3.8 4.9 7.0 0.3 2.3 2 0 0 2 2 2 0 Gas vesicle protein G Methyltransf_16 PF10294.4 EEQ72603.1 - 1.3e-22 80.0 0.0 2.6e-22 79.1 0.0 1.4 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 EEQ72603.1 - 0.00025 21.0 0.1 0.00052 20.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ72603.1 - 0.0003 20.5 0.0 0.00046 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ72603.1 - 0.056 12.8 0.0 0.11 11.8 0.0 1.4 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_18 PF12847.2 EEQ72603.1 - 0.087 13.4 0.1 0.19 12.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DEAD PF00270.24 EEQ72605.1 - 3.2e-26 91.8 0.1 3e-25 88.6 0.1 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ72605.1 - 4.1e-22 77.8 0.1 1.3e-21 76.2 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ72605.1 - 1.4e-05 25.0 0.0 3.8e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EEQ72605.1 - 0.026 12.9 0.0 3.4 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) T4SS-DNA_transf PF02534.9 EEQ72605.1 - 0.053 12.1 0.0 0.11 11.0 0.0 1.4 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer SbcCD_C PF13558.1 EEQ72605.1 - 0.067 13.1 0.1 0.32 10.9 0.0 2.1 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATP-synt_G PF04718.10 EEQ72606.1 - 4.3e-30 104.4 0.0 1e-29 103.1 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit ADH_N PF08240.7 EEQ72608.1 - 1.2e-28 99.0 1.3 2.5e-28 98.0 0.4 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ72608.1 - 1.5e-11 43.9 0.0 3.3e-11 42.8 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EEQ72608.1 - 0.083 12.2 0.1 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Beta-lactamase PF00144.19 EEQ72609.1 - 2.9e-44 151.4 0.0 5.1e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.1 EEQ72609.1 - 0.00052 19.5 0.0 0.0059 16.0 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase enzyme family Peptidase_S11 PF00768.15 EEQ72609.1 - 0.0065 15.7 0.1 0.02 14.1 0.0 2.0 2 1 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase ELO PF01151.13 EEQ72610.1 - 6.3e-86 287.7 3.3 7.6e-86 287.4 2.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Myb_DNA-bind_6 PF13921.1 EEQ72611.1 - 0.011 15.8 0.0 0.73 9.9 0.0 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain GMP_synt_C PF00958.17 EEQ72613.1 - 8.9e-39 131.1 0.0 3.6e-38 129.1 0.0 2.0 2 0 0 2 2 2 1 GMP synthase C terminal domain GATase PF00117.23 EEQ72613.1 - 4.6e-38 130.6 0.0 9.1e-38 129.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 EEQ72613.1 - 4.8e-12 45.2 0.2 1.6e-06 27.2 0.1 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EEQ72613.1 - 1.2e-08 34.7 0.0 2.1e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.8 EEQ72613.1 - 0.00034 19.9 0.0 0.058 12.6 0.0 2.1 2 0 0 2 2 2 2 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 EEQ72613.1 - 0.0006 19.3 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.9 EEQ72613.1 - 0.00083 18.8 0.0 0.006 16.0 0.0 2.0 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 EEQ72613.1 - 0.0014 17.2 0.1 0.0057 15.2 0.0 1.9 2 0 0 2 2 2 1 tRNA methyl transferase PAPS_reduct PF01507.14 EEQ72613.1 - 0.015 15.0 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.14 EEQ72613.1 - 0.024 13.6 0.1 0.053 12.5 0.1 1.5 2 0 0 2 2 2 0 Arginosuccinate synthase ATP_bind_3 PF01171.15 EEQ72613.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 PP-loop family PHD PF00628.24 EEQ72614.1 - 3.3e-05 23.4 8.9 0.0001 21.8 6.2 1.9 1 0 0 1 1 1 1 PHD-finger Chibby PF14645.1 EEQ72614.1 - 0.0096 15.8 0.2 0.023 14.5 0.1 1.6 1 0 0 1 1 1 1 Chibby family Mod_r PF07200.8 EEQ72614.1 - 0.57 10.0 6.2 0.86 9.5 2.4 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein ADH_N PF08240.7 EEQ72615.1 - 1.1e-12 47.6 0.0 2.1e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TruD PF01142.13 EEQ72617.1 - 4.8e-53 180.1 0.0 3.3e-50 170.8 0.0 3.5 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Acetyltransf_1 PF00583.19 EEQ72618.1 - 8.2e-11 41.7 0.0 2.8e-10 40.0 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ72618.1 - 4.4e-07 29.9 0.0 1.3e-05 25.2 0.0 2.8 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEQ72618.1 - 9.3e-05 22.2 0.1 0.014 15.2 0.0 3.2 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEQ72618.1 - 0.00024 21.1 0.2 0.0052 16.8 0.0 2.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ72618.1 - 0.0077 15.9 0.1 0.043 13.5 0.1 2.1 1 1 0 1 1 1 1 FR47-like protein MOZ_SAS PF01853.13 EEQ72618.1 - 0.013 14.7 0.0 0.055 12.6 0.0 1.9 2 0 0 2 2 2 0 MOZ/SAS family RPE65 PF03055.10 EEQ72619.1 - 1.3e-118 396.6 0.0 1.6e-118 396.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein TOM20_plant PF06552.7 EEQ72619.1 - 0.21 11.1 0.1 0.44 10.1 0.1 1.5 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 DUF2293 PF10056.4 EEQ72620.1 - 2.6e-30 104.2 1.0 2.6e-30 104.2 0.7 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) PHD PF00628.24 EEQ72623.1 - 9.9e-09 34.7 7.8 1.8e-08 33.9 5.4 1.5 1 0 0 1 1 1 1 PHD-finger CPSF73-100_C PF11718.3 EEQ72624.1 - 1.5e-70 236.8 0.0 3.4e-69 232.5 0.0 2.2 1 1 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EEQ72624.1 - 1e-31 109.5 0.0 2.3e-31 108.3 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 EEQ72624.1 - 2.2e-07 30.5 0.1 4.7e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 EEQ72624.1 - 4.2e-05 23.1 0.0 9.7e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EEQ72624.1 - 0.0003 20.4 0.0 0.55 9.8 0.0 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily TAF4 PF05236.9 EEQ72625.1 - 4.4e-19 68.7 0.1 2.1e-06 27.2 0.0 3.2 3 0 0 3 3 3 3 Transcription initiation factor TFIID component TAF4 family DUF1180 PF06679.7 EEQ72626.1 - 6 6.7 7.3 1.7 8.5 3.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Pkinase PF00069.20 EEQ72627.1 - 4.6e-51 173.4 0.1 8.2e-51 172.6 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ72627.1 - 1.1e-14 54.2 0.0 4.5e-14 52.1 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase PRCC PF10253.4 EEQ72627.1 - 0.25 11.9 10.9 0.034 14.8 4.1 2.1 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Mtc PF03820.12 EEQ72628.1 - 8.4e-102 339.9 0.0 1.8e-101 338.8 0.0 1.5 1 1 0 1 1 1 1 Tricarboxylate carrier Trypsin_2 PF13365.1 EEQ72629.1 - 2e-05 24.5 0.0 5.9e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain PDZ PF00595.19 EEQ72629.1 - 0.00011 22.3 0.3 0.0018 18.4 0.1 2.3 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EEQ72629.1 - 0.0027 17.5 0.1 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 PDZ domain Scytalone_dh PF02982.9 EEQ72629.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Scytalone dehydratase UPRTase PF14681.1 EEQ72631.1 - 1.8e-32 112.2 0.3 3.5e-32 111.2 0.2 1.5 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EEQ72631.1 - 4.9e-06 26.2 0.4 0.0093 15.6 0.1 2.4 1 1 1 2 2 2 2 Phosphoribosyl transferase domain PRTase_2 PF15609.1 EEQ72631.1 - 0.016 14.5 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase Aminotran_3 PF00202.16 EEQ72632.1 - 1.9e-86 290.0 0.0 2.2e-86 289.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Acetyltransf_3 PF13302.1 EEQ72633.1 - 5.9e-29 101.0 0.0 7e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EEQ72633.1 - 1.9e-11 44.1 0.0 2.2e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEQ72633.1 - 1.9e-09 37.3 0.0 2.9e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EEQ72633.1 - 0.016 15.0 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SRP19 PF01922.12 EEQ72634.1 - 3.3e-31 107.7 0.1 4.9e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein Fungal_trans PF04082.13 EEQ72635.1 - 7.5e-16 57.7 0.0 1.3e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ72635.1 - 8.4e-09 35.1 10.0 1.6e-08 34.3 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FGGY_N PF00370.16 EEQ72635.1 - 0.06 12.6 0.3 0.13 11.5 0.2 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain TCTP PF00838.12 EEQ72636.1 - 1.3e-41 142.3 0.0 1.6e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 Translationally controlled tumour protein FliE PF02049.13 EEQ72636.1 - 0.051 13.6 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE IpaD PF06511.6 EEQ72636.1 - 0.07 12.1 0.1 0.082 11.9 0.0 1.1 1 0 0 1 1 1 0 Invasion plasmid antigen IpaD FA_hydroxylase PF04116.8 EEQ72638.1 - 2.9e-18 66.3 12.0 2.9e-18 66.3 8.3 2.1 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily GMC_oxred_N PF00732.14 EEQ72640.1 - 2.3e-45 155.0 1.6 3.5e-45 154.4 1.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EEQ72640.1 - 7.6e-28 97.6 0.4 2.2e-27 96.1 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EEQ72640.1 - 3.1e-06 26.3 0.1 0.01 14.7 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEQ72640.1 - 9.5e-05 21.4 3.2 0.0002 20.3 2.2 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EEQ72640.1 - 0.00025 21.0 0.1 0.0014 18.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEQ72640.1 - 0.0008 19.3 1.0 0.011 15.7 0.2 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EEQ72640.1 - 0.0042 16.1 0.0 0.0059 15.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EEQ72640.1 - 0.063 12.3 0.4 0.18 10.8 0.3 1.7 1 0 0 1 1 1 0 Thi4 family Thiolase_C PF02803.13 EEQ72641.1 - 4.4e-10 39.0 0.1 1.6e-09 37.2 0.1 2.0 1 1 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EEQ72641.1 - 0.0005 19.6 0.3 0.0029 17.1 0.2 2.0 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 EEQ72641.1 - 0.055 12.4 0.0 3.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Thiolase, N-terminal domain Kelch_5 PF13854.1 EEQ72642.1 - 2.6e-14 52.8 11.6 2.7e-11 43.1 2.8 4.0 4 0 0 4 4 4 3 Kelch motif DEAD PF00270.24 EEQ72644.1 - 1.4e-31 109.2 0.0 3.5e-15 55.8 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ72644.1 - 3.2e-17 62.1 0.1 7.7e-17 60.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ72644.1 - 2.1e-08 34.2 0.0 7.2e-08 32.4 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ACP_syn_III_C PF08541.5 EEQ72644.1 - 0.11 12.5 0.1 0.48 10.4 0.0 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal PIGA PF08288.7 EEQ72645.1 - 1.3e-46 156.9 4.3 1.6e-46 156.6 1.0 2.2 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EEQ72645.1 - 8.7e-30 103.3 0.0 1.3e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EEQ72645.1 - 2.3e-17 63.3 0.0 3.9e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EEQ72645.1 - 2.9e-10 40.1 0.8 6.9e-10 38.9 0.6 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EEQ72645.1 - 5.4e-10 39.6 0.0 1e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EEQ72645.1 - 0.0018 18.5 0.0 0.0047 17.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Arf PF00025.16 EEQ72646.1 - 2e-38 131.3 0.0 2e-25 89.0 0.0 2.4 2 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 EEQ72646.1 - 5.7e-12 45.0 0.0 2.9e-05 22.9 0.0 2.2 1 1 0 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EEQ72646.1 - 1.1e-07 32.3 0.0 1.7e-06 28.5 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EEQ72646.1 - 4.8e-07 29.7 0.0 9e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EEQ72646.1 - 1.4e-06 27.6 0.0 0.0001 21.5 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EEQ72646.1 - 1.5e-06 27.5 0.0 2.4e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EEQ72646.1 - 2.2e-06 27.1 0.0 0.00092 18.6 0.0 2.4 2 1 0 2 2 2 2 Ras family GTP_EFTU PF00009.22 EEQ72646.1 - 2.3e-05 23.9 0.0 0.00077 18.9 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EEQ72646.1 - 0.0069 16.2 0.0 0.29 10.9 0.1 2.2 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.1 EEQ72646.1 - 0.008 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FeoB_N PF02421.13 EEQ72646.1 - 0.13 11.4 0.1 0.27 10.4 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Nol1_Nop2_Fmu PF01189.12 EEQ72647.1 - 9.7e-11 41.5 0.0 2.9e-05 23.6 0.0 2.6 3 0 0 3 3 3 2 NOL1/NOP2/sun family Acetyltransf_1 PF00583.19 EEQ72648.1 - 2.6e-08 33.7 0.0 5.9e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.1 EEQ72648.1 - 8.4e-06 26.2 0.0 2.7e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEQ72648.1 - 6.4e-05 23.0 0.0 9.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEQ72648.1 - 0.00092 19.0 0.1 0.0019 18.0 0.1 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 EEQ72648.1 - 0.0014 18.7 0.0 0.0022 18.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEQ72648.1 - 0.0017 18.4 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ72648.1 - 0.079 12.7 0.3 0.35 10.6 0.2 1.9 1 1 0 1 1 1 0 FR47-like protein FYVE PF01363.16 EEQ72649.1 - 9.5e-15 54.2 6.0 1.5e-14 53.6 4.1 1.3 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 EEQ72649.1 - 0.0049 16.7 0.9 0.011 15.5 0.6 1.5 1 0 0 1 1 1 1 IBR domain DUF4587 PF15248.1 EEQ72649.1 - 0.04 14.5 0.4 0.11 13.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4587) zf-AN1 PF01428.11 EEQ72649.1 - 0.17 11.8 10.4 0.32 10.9 7.2 1.4 1 0 0 1 1 1 0 AN1-like Zinc finger BTB_2 PF02214.17 EEQ72650.1 - 1.7e-08 34.5 0.0 0.00011 22.3 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.26 EEQ72650.1 - 0.00094 19.1 0.0 0.047 13.6 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain GST_C_3 PF14497.1 EEQ72652.1 - 0.00032 21.1 0.0 0.00062 20.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EEQ72652.1 - 0.0079 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEQ72652.1 - 0.034 14.0 0.0 0.077 12.8 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PilM_2 PF11104.3 EEQ72653.1 - 0.011 14.5 0.7 0.013 14.3 0.5 1.0 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; Tom37_C PF11801.3 EEQ72653.1 - 2.4 8.0 7.5 0.16 11.8 1.3 1.8 1 1 1 2 2 2 0 Tom37 C-terminal domain Alpha_kinase PF02816.13 EEQ72655.1 - 2.8e-08 33.6 0.1 4.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family CAP_N PF01213.14 EEQ72657.1 - 5.6e-62 209.8 8.1 5.4e-42 144.1 0.0 2.5 2 0 0 2 2 2 2 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EEQ72657.1 - 1.2e-56 190.4 2.1 1.6e-56 190.0 1.4 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal PEP-utilisers_N PF05524.8 EEQ72657.1 - 0.0079 15.9 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal TBCC PF07986.7 EEQ72657.1 - 0.17 11.3 2.7 0.23 10.8 1.3 1.6 1 1 0 1 1 1 0 Tubulin binding cofactor C DUF4041 PF13250.1 EEQ72657.1 - 0.39 10.3 2.0 2.4 7.7 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4041) PfkB PF00294.19 EEQ72658.1 - 1.5e-16 60.3 0.0 3e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ribonucleas_3_3 PF14622.1 EEQ72660.1 - 1.7e-06 27.9 0.0 0.0043 16.9 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EEQ72660.1 - 2.8e-06 27.7 0.0 6.6e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease III domain BSP PF04450.7 EEQ72661.1 - 2.2e-66 223.2 0.0 7.2e-64 215.0 0.0 2.1 2 0 0 2 2 2 2 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 EEQ72661.1 - 0.004 17.1 0.0 0.0073 16.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily TFIIA PF03153.8 EEQ72661.1 - 0.023 14.6 0.5 0.04 13.8 0.3 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SprT-like PF10263.4 EEQ72661.1 - 0.037 13.6 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 SprT-like family CLASP_N PF12348.3 EEQ72662.1 - 1.7e-151 501.9 0.1 8.2e-86 287.0 0.0 2.8 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 EEQ72662.1 - 8.7e-10 37.8 0.1 0.011 15.8 0.0 5.7 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 EEQ72662.1 - 4.1e-08 33.3 0.4 0.045 14.0 0.0 4.8 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 EEQ72662.1 - 0.00077 19.8 0.5 1.2 9.6 0.0 3.7 3 0 0 3 3 3 2 HEAT-like repeat Cnd1 PF12717.2 EEQ72662.1 - 0.0015 18.4 0.0 0.022 14.5 0.0 2.8 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EEQ72662.1 - 0.084 12.7 0.0 67 3.5 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat APH PF01636.18 EEQ72663.1 - 4.1e-07 29.9 0.1 6.5e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ72663.1 - 0.014 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2607 PF10795.4 EEQ72664.1 - 0.014 15.2 0.1 0.015 15.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) Transposase_21 PF02992.9 EEQ72664.1 - 0.014 14.4 0.1 0.044 12.8 0.0 1.7 1 1 1 2 2 2 0 Transposase family tnp2 G10 PF01125.12 EEQ72665.1 - 0.0074 15.8 0.2 3.3 7.2 0.0 2.4 1 1 0 2 2 2 2 G10 protein Carb_anhydrase PF00194.16 EEQ72665.1 - 0.18 10.7 1.3 5.7 5.8 0.0 2.7 1 1 2 3 3 3 0 Eukaryotic-type carbonic anhydrase Pneumo_M2 PF07380.6 EEQ72665.1 - 0.25 11.3 1.5 13 5.8 0.1 2.4 1 1 1 2 2 2 0 Pneumovirus M2 protein TGT_C1 PF14809.1 EEQ72665.1 - 1.2 9.0 7.2 28 4.5 0.3 3.5 3 0 0 3 3 3 0 C1 domain of tRNA-guanine transglycosylase dimerisation TrbI_Ftype PF09677.5 EEQ72665.1 - 2.9 7.7 5.1 7.6 6.4 0.3 2.9 2 2 1 3 3 3 0 Type-F conjugative transfer system protein (TrbI_Ftype) DUF506 PF04720.7 EEQ72666.1 - 0.05 13.2 0.4 0.061 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF506) DUF688 PF05097.7 EEQ72666.1 - 0.071 12.0 0.4 0.077 11.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) Voldacs PF03517.8 EEQ72666.1 - 0.072 12.9 5.1 0.13 12.1 3.5 1.5 1 1 0 1 1 1 0 Regulator of volume decrease after cellular swelling Plasmid_stab_B PF10784.4 EEQ72666.1 - 0.077 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Plasmid stability protein Flavi_NS2A PF01005.14 EEQ72666.1 - 0.12 11.6 0.2 0.16 11.2 0.1 1.1 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2A PBP1_TM PF14812.1 EEQ72666.1 - 5.6 7.3 8.9 9.3 6.6 6.2 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 EEQ72666.1 - 7.9 5.9 7.6 2.5 7.6 3.1 1.7 2 0 0 2 2 2 0 Nucleoplasmin RhoGAP PF00620.22 EEQ72668.1 - 4.8e-46 156.1 0.0 1.3e-45 154.7 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EEQ72668.1 - 2.5e-14 53.0 18.2 9.9e-10 38.3 1.5 2.4 2 0 0 2 2 2 2 LIM domain CmcI PF04989.7 EEQ72668.1 - 0.12 11.6 0.5 0.26 10.5 0.4 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase eIF3_N PF09440.5 EEQ72668.1 - 2.9 8.0 8.1 11 6.1 0.2 2.6 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain Zn-ribbon_8 PF09723.5 EEQ72668.1 - 3.1 7.8 20.2 0.67 9.9 1.0 4.2 3 1 1 4 4 4 0 Zinc ribbon domain DASH_Ask1 PF08655.5 EEQ72669.1 - 2.7e-19 68.7 1.2 7.2e-16 57.7 0.0 2.4 2 0 0 2 2 2 2 DASH complex subunit Ask1 ARA70 PF12489.3 EEQ72669.1 - 0.033 14.1 0.4 0.069 13.1 0.3 1.5 1 0 0 1 1 1 0 Nuclear coactivator DUF4410 PF14366.1 EEQ72671.1 - 0.18 11.5 0.4 0.96 9.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4410) DUF4210 PF13915.1 EEQ72674.1 - 4.3e-28 97.3 0.0 3.3e-27 94.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 EEQ72674.1 - 3.5e-23 81.2 0.3 7.9e-23 80.1 0.2 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis rRNA_processing PF08524.6 EEQ72675.1 - 0.1 12.3 21.6 7.1 6.4 15.0 2.2 1 1 0 1 1 1 0 rRNA processing Phlebovirus_NSM PF07246.6 EEQ72675.1 - 5.6 6.0 6.8 0.8 8.8 1.9 1.5 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Spc97_Spc98 PF04130.8 EEQ72676.1 - 4.9e-72 242.9 0.6 6.2e-72 242.6 0.4 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family TetR_C_2 PF08361.6 EEQ72676.1 - 0.07 13.0 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 MAATS-type transcriptional repressor, C-terminal region Eaf7 PF07904.8 EEQ72677.1 - 4.1e-27 93.9 0.0 6.9e-27 93.2 0.0 1.4 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 NOA36 PF06524.7 EEQ72677.1 - 2.2 7.4 7.6 3.2 6.9 5.2 1.2 1 0 0 1 1 1 0 NOA36 protein Iso_dh PF00180.15 EEQ72678.1 - 6.9e-100 334.3 0.0 8.7e-100 334.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.2 EEQ72678.1 - 0.11 12.4 0.1 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif Sec5 PF15469.1 EEQ72679.1 - 1.2e-31 109.8 0.0 1.7e-30 106.1 0.0 2.4 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 EEQ72679.1 - 7e-05 22.5 0.0 0.00024 20.8 0.0 2.0 1 0 0 1 1 1 1 Vps51/Vps67 Mo-co_dimer PF03404.11 EEQ72680.1 - 1.7e-57 192.6 0.4 3.3e-57 191.7 0.3 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 EEQ72680.1 - 2.6e-38 131.0 0.0 7.1e-38 129.6 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 EEQ72680.1 - 1.2e-27 95.9 0.0 2.6e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EEQ72680.1 - 6.5e-24 84.5 0.0 1.2e-23 83.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 EEQ72680.1 - 5.5e-21 74.1 0.0 1.2e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 EEQ72680.1 - 0.0067 16.3 0.1 0.17 11.7 0.0 2.4 1 1 1 2 2 2 1 Ferric reductase NAD binding domain FMN_dh PF01070.13 EEQ72681.1 - 2.9e-62 210.5 1.7 2.5e-35 122.0 0.0 3.0 1 1 2 3 3 3 3 FMN-dependent dehydrogenase ThiG PF05690.9 EEQ72681.1 - 5.2e-05 22.4 0.8 0.051 12.6 0.0 2.2 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 EEQ72681.1 - 5.7e-05 22.1 0.2 0.17 10.7 0.1 2.5 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain PI-PLC-X PF00388.14 EEQ72684.1 - 1.1e-60 203.3 0.0 2.1e-60 202.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EEQ72684.1 - 7.7e-40 135.5 0.2 1.6e-39 134.5 0.2 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EEQ72684.1 - 1.7e-08 34.3 0.1 1.1e-07 31.7 0.0 2.2 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 EEQ72684.1 - 1.1e-06 28.3 0.0 2.9e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 C2 domain GDPD PF03009.12 EEQ72684.1 - 0.0052 16.3 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family EF-hand_8 PF13833.1 EEQ72684.1 - 0.0094 15.5 0.4 0.06 12.9 0.0 2.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 EEQ72684.1 - 0.012 15.4 0.4 5.7 7.0 0.1 2.8 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.27 EEQ72684.1 - 0.023 13.9 0.2 0.19 11.1 0.0 2.4 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.1 EEQ72684.1 - 0.045 13.9 0.3 0.32 11.1 0.1 2.4 1 1 2 3 3 3 0 EF-hand domain pair CATSPERB PF15149.1 EEQ72684.1 - 0.12 10.5 0.0 0.31 9.1 0.0 1.6 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit beta protein family adh_short PF00106.20 EEQ72685.1 - 1.4e-20 73.8 0.7 1.9e-20 73.4 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ72685.1 - 3.5e-19 69.5 0.0 4.2e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ72685.1 - 6.2e-06 25.9 0.8 1.1e-05 25.2 0.5 1.4 1 1 0 1 1 1 1 KR domain YjeF_N PF03853.10 EEQ72685.1 - 0.056 13.0 0.2 0.094 12.3 0.2 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus AhpC-TSA_2 PF13911.1 EEQ72686.1 - 8.5e-14 51.4 0.0 1.5e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EEQ72686.1 - 1.4e-05 24.7 0.0 2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EEQ72686.1 - 0.028 13.9 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Redoxin UPF1_Zn_bind PF09416.5 EEQ72687.1 - 3.5e-74 247.4 2.4 6.4e-74 246.6 1.7 1.5 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 EEQ72687.1 - 4.7e-59 199.1 0.0 7.1e-59 198.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEQ72687.1 - 1.9e-57 194.5 1.2 2.8e-57 194.0 0.9 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ72687.1 - 1.4e-14 53.5 0.1 4.3e-14 52.0 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EEQ72687.1 - 2.2e-12 46.9 0.3 5.1e-11 42.5 0.2 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EEQ72687.1 - 4.5e-09 36.3 0.0 8.6e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EEQ72687.1 - 2.8e-05 23.7 0.1 0.23 10.9 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EEQ72687.1 - 0.00021 20.3 0.8 0.0017 17.3 0.0 2.6 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 EEQ72687.1 - 0.00053 19.3 0.0 0.0065 15.8 0.0 2.3 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 EEQ72687.1 - 0.0015 18.1 0.0 0.0031 17.1 0.0 1.5 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 EEQ72687.1 - 0.0023 16.9 0.1 0.47 9.3 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase DEAD PF00270.24 EEQ72687.1 - 0.0055 16.2 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_S13_N PF08069.7 EEQ72687.1 - 0.0097 15.7 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain KaiC PF06745.8 EEQ72687.1 - 0.015 14.4 0.0 0.049 12.7 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.1 EEQ72687.1 - 0.034 13.5 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.18 EEQ72687.1 - 0.035 13.5 0.0 0.09 12.1 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 EEQ72687.1 - 0.053 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EEQ72687.1 - 0.087 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 EEQ72687.1 - 0.1 11.8 0.0 0.24 10.6 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.24 EEQ72687.1 - 0.17 12.0 0.4 0.54 10.4 0.3 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Brix PF04427.13 EEQ72688.1 - 3.7e-45 153.9 0.1 4.5e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Brix domain IGPS PF00218.16 EEQ72690.1 - 2.8e-95 318.2 0.0 1.7e-93 312.3 0.0 2.1 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EEQ72690.1 - 2.5e-56 190.3 0.0 4.8e-54 182.9 0.0 2.4 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EEQ72690.1 - 1.4e-50 171.3 0.0 2.5e-50 170.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EEQ72690.1 - 4.7e-06 26.2 0.0 9.3e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 EEQ72690.1 - 0.019 14.4 0.1 0.075 12.5 0.0 2.0 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.16 EEQ72690.1 - 0.019 14.2 0.1 0.088 12.0 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein NanE PF04131.9 EEQ72690.1 - 0.02 13.8 0.3 0.37 9.7 0.0 2.4 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase PTCB-BRCT PF12738.2 EEQ72691.1 - 1.9e-07 30.8 0.0 3.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EEQ72691.1 - 0.00014 21.9 0.1 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain WGR PF05406.10 EEQ72691.1 - 0.0038 17.1 0.1 0.009 15.9 0.0 1.6 1 0 0 1 1 1 1 WGR domain Nup188 PF10487.4 EEQ72692.1 - 4.1e-55 187.2 0.6 7.2e-55 186.4 0.4 1.3 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 DUF465 PF04325.8 EEQ72692.1 - 0.088 12.5 0.0 0.23 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF465) Pkinase PF00069.20 EEQ72694.1 - 0.079 12.0 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain AMP-binding PF00501.23 EEQ72695.1 - 4e-90 302.1 0.0 5.1e-90 301.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ72695.1 - 3e-11 44.1 0.0 6.6e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Use1 PF09753.4 EEQ72699.1 - 2.5e-06 27.1 2.4 7.1e-06 25.6 1.7 1.9 1 1 0 1 1 1 1 Membrane fusion protein Use1 V-SNARE PF05008.10 EEQ72699.1 - 0.041 14.0 2.9 0.043 13.9 0.2 2.2 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus GldM_N PF12081.3 EEQ72699.1 - 0.061 12.8 1.5 0.13 11.7 0.2 1.9 2 0 0 2 2 2 0 GldM N-terminal domain Ring_hydroxyl_A PF00848.14 EEQ72699.1 - 0.076 12.6 1.5 0.1 12.2 1.1 1.3 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) PEP-utilisers_N PF05524.8 EEQ72699.1 - 0.14 12.0 1.8 0.76 9.5 0.1 2.4 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF3573 PF12097.3 EEQ72699.1 - 0.44 9.1 2.1 0.2 10.2 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) DUF605 PF04652.11 EEQ72699.1 - 0.45 9.8 25.2 0.58 9.4 17.5 1.1 1 0 0 1 1 1 0 Vta1 like Tmemb_cc2 PF10267.4 EEQ72699.1 - 0.5 8.8 7.4 0.072 11.6 0.8 2.0 1 1 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein ADIP PF11559.3 EEQ72699.1 - 2.8 7.8 15.2 0.23 11.3 0.1 2.7 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding SLX9 PF15341.1 EEQ72699.1 - 6.1 7.2 8.7 3.2 8.1 1.3 2.4 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 G-alpha PF00503.15 EEQ72700.1 - 5.5e-131 436.8 3.1 6.8e-131 436.5 2.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EEQ72700.1 - 6.6e-16 58.0 1.6 9.6e-11 41.2 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 EEQ72700.1 - 0.00036 20.0 0.0 0.0016 17.9 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 EEQ72700.1 - 0.001 19.5 0.1 2.5 8.6 0.0 2.8 2 1 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EEQ72700.1 - 0.0011 18.2 2.4 0.072 12.2 0.0 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EEQ72700.1 - 0.017 14.5 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EEQ72700.1 - 0.018 14.5 0.2 0.048 13.1 0.1 1.7 1 1 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EEQ72700.1 - 0.068 13.1 0.0 13 5.7 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EEQ72700.1 - 0.086 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.1 EEQ72700.1 - 0.21 11.8 3.3 0.1 12.9 0.1 2.0 1 1 1 2 2 2 0 AAA domain CH PF00307.26 EEQ72702.1 - 1.6e-35 121.3 0.1 1.9e-18 66.4 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EEQ72702.1 - 1.7e-27 95.1 0.1 4.8e-27 93.7 0.0 1.9 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EEQ72702.1 - 4.6e-11 42.2 0.2 4.7e-07 29.3 0.0 3.0 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_8 PF13833.1 EEQ72702.1 - 0.00075 19.0 0.1 0.0038 16.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EEQ72702.1 - 0.0015 18.2 0.1 0.012 15.3 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain Spectrin PF00435.16 EEQ72702.1 - 0.0056 16.9 8.7 1.7 8.9 3.3 2.9 3 0 0 3 3 3 2 Spectrin repeat EF-hand_1 PF00036.27 EEQ72702.1 - 0.0076 15.4 0.1 0.069 12.4 0.0 2.6 2 0 0 2 2 2 1 EF hand EIAV_Rev PF11129.3 EEQ72702.1 - 0.073 13.0 2.4 0.21 11.5 1.6 1.7 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus RRM_1 PF00076.17 EEQ72703.1 - 1.7e-17 62.7 0.0 2.8e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ72703.1 - 3.6e-11 42.8 0.0 6e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EEQ72703.1 - 8.2e-07 29.3 9.6 8.2e-07 29.3 6.6 3.6 4 0 0 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EEQ72703.1 - 8.7e-05 22.2 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EEQ72704.1 - 1.6e-29 100.6 2.2 7.7e-10 38.2 0.0 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 EEQ72704.1 - 0.00044 18.5 0.2 0.12 10.5 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Me-amine-dh_H PF06433.6 EEQ72704.1 - 0.00054 18.7 0.0 0.2 10.2 0.0 2.2 2 0 0 2 2 2 2 Methylamine dehydrogenase heavy chain (MADH) PUL PF08324.6 EEQ72705.1 - 9.6e-57 191.8 0.1 1.3e-56 191.4 0.1 1.1 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 EEQ72705.1 - 3e-43 146.5 0.1 5.7e-43 145.6 0.0 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 EEQ72705.1 - 8e-42 139.6 17.8 2.1e-08 33.7 0.9 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat GCV_T_C PF08669.6 EEQ72705.1 - 0.096 12.7 0.0 0.43 10.6 0.0 2.1 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain YjeF_N PF03853.10 EEQ72706.1 - 2.8e-34 118.1 0.0 3.7e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus Ribosomal_S16 PF00886.14 EEQ72707.1 - 4.5e-25 87.1 0.0 6.2e-25 86.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 RRM_1 PF00076.17 EEQ72712.1 - 2.6e-15 55.7 0.0 1.4e-13 50.2 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ72712.1 - 2.8e-07 30.4 0.0 7.4e-05 22.6 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ72712.1 - 0.076 12.8 0.0 20 5.0 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bot1p PF12298.3 EEQ72713.1 - 7.8e-56 188.7 2.5 7.8e-56 188.7 1.7 2.2 3 0 0 3 3 3 1 Eukaryotic mitochondrial regulator protein Response_reg PF00072.19 EEQ72714.1 - 2.9e-19 69.1 0.0 2.5e-12 46.7 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain ProSAAS PF07259.7 EEQ72716.1 - 0.0044 16.5 0.4 0.0055 16.2 0.3 1.1 1 0 0 1 1 1 1 ProSAAS precursor DUF3676 PF12429.3 EEQ72716.1 - 0.17 11.5 0.6 0.21 11.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3676) Leader_Trp PF08255.6 EEQ72716.1 - 0.57 9.9 5.4 0.47 10.2 1.1 2.4 2 0 0 2 2 2 0 Trp-operon Leader Peptide SH3_1 PF00018.23 EEQ72717.1 - 5.2e-09 35.3 0.1 1.3e-08 34.0 0.1 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EEQ72717.1 - 4.4e-06 26.1 0.0 1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EEQ72717.1 - 2.5e-05 23.6 0.0 5.4e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DIE2_ALG10 PF04922.7 EEQ72717.1 - 0.066 12.2 1.2 0.091 11.7 0.8 1.1 1 0 0 1 1 1 0 DIE2/ALG10 family Bac_chlorC PF02043.12 EEQ72717.1 - 0.44 10.3 3.9 0.61 9.9 0.3 2.8 3 0 0 3 3 3 0 Bacteriochlorophyll C binding protein Herpes_LMP1 PF05297.6 EEQ72717.1 - 0.6 8.9 4.8 0.25 10.2 0.1 1.9 1 1 1 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) ABC_tran PF00005.22 EEQ72720.1 - 3.4e-06 27.3 0.0 6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Fungal_trans PF04082.13 EEQ72721.1 - 2.7e-20 72.3 0.1 4.2e-20 71.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ72721.1 - 2.4e-09 36.9 12.9 4.3e-09 36.1 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1192 PF06698.6 EEQ72721.1 - 0.49 10.2 1.8 3.2 7.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) MFS_1 PF07690.11 EEQ72722.1 - 1.7e-34 119.0 18.0 1.7e-34 119.0 12.5 3.7 3 1 1 4 4 4 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ72722.1 - 1.9e-11 43.2 8.8 1.9e-11 43.2 6.1 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EEQ72722.1 - 6.2e-09 34.6 11.1 5.9e-06 24.7 2.6 2.1 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DAO PF01266.19 EEQ72723.1 - 1.2e-51 175.7 0.1 1.4e-51 175.4 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EEQ72723.1 - 1.2e-05 25.4 1.0 0.064 13.3 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEQ72723.1 - 4e-05 23.5 0.2 0.00013 21.9 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EEQ72723.1 - 0.0003 19.9 0.3 0.00056 19.0 0.2 1.3 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.1 EEQ72723.1 - 0.0013 17.7 0.3 0.0072 15.2 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 EEQ72723.1 - 0.005 15.7 1.5 0.19 10.5 0.5 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EEQ72723.1 - 0.021 13.7 0.4 0.038 12.9 0.3 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Glyco_transf_34 PF05637.7 EEQ72723.1 - 0.043 13.3 0.1 0.068 12.6 0.1 1.2 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Pyr_redox_2 PF07992.9 EEQ72723.1 - 0.046 13.5 0.8 0.7 9.7 0.3 2.2 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEQ72723.1 - 0.054 13.2 1.0 0.27 10.9 0.1 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding La PF05383.12 EEQ72724.1 - 1.7e-16 59.7 0.1 2.7e-16 59.0 0.1 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EEQ72724.1 - 3.2e-06 26.6 0.1 8e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ72724.1 - 3.6e-06 26.8 0.0 1.4e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ72724.1 - 0.003 17.3 0.0 0.0068 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Chitin_synth_2 PF03142.10 EEQ72725.1 - 3.1e-25 88.5 1.2 3.1e-25 88.5 0.8 2.6 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EEQ72725.1 - 2.8e-17 63.0 3.7 2.8e-17 63.0 2.5 2.5 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EEQ72725.1 - 3.6e-14 53.1 0.0 7.8e-14 52.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EEQ72725.1 - 0.079 12.6 0.0 8.7 5.9 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 HSP70 PF00012.15 EEQ72726.1 - 3.3e-169 563.6 0.1 6.5e-169 562.6 0.0 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEQ72726.1 - 3.3e-10 39.0 0.6 6.6e-10 38.0 0.0 1.7 3 0 0 3 3 3 1 MreB/Mbl protein FtsA PF14450.1 EEQ72726.1 - 0.0017 18.1 1.5 1.4 8.7 0.1 3.3 2 2 0 2 2 2 2 Cell division protein FtsA Trans_reg_C PF00486.23 EEQ72726.1 - 0.085 12.7 0.1 0.81 9.6 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal V_ATPase_I PF01496.14 EEQ72726.1 - 0.15 9.8 3.3 0.22 9.3 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DMPK_coil PF08826.5 EEQ72726.1 - 0.49 10.3 4.9 0.6 10.0 0.5 3.0 3 0 0 3 3 3 0 DMPK coiled coil domain like Pkinase PF00069.20 EEQ72728.1 - 0.0041 16.3 0.0 0.008 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Rox3 PF08633.5 EEQ72729.1 - 2.1e-51 174.9 0.9 4.3e-51 173.9 0.1 1.9 2 0 0 2 2 2 1 Rox3 mediator complex subunit HAD_2 PF13419.1 EEQ72730.1 - 3e-31 109.0 0.0 4.2e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ72730.1 - 0.0049 16.5 0.0 0.0094 15.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EEQ72730.1 - 0.027 14.9 0.0 0.05 14.0 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Thr_synth_N PF14821.1 EEQ72731.1 - 4.1e-29 100.4 0.0 7.8e-29 99.5 0.0 1.5 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 EEQ72731.1 - 8.1e-16 58.1 0.0 2.6e-15 56.4 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4202 PF13875.1 EEQ72732.1 - 2.4e-84 281.6 2.3 2.6e-84 281.4 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) SPAM PF02090.10 EEQ72732.1 - 0.082 12.8 0.7 0.16 11.9 0.5 1.4 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein Sod_Fe_C PF02777.13 EEQ72732.1 - 0.1 12.4 0.2 0.72 9.7 0.0 2.2 2 0 0 2 2 2 0 Iron/manganese superoxide dismutases, C-terminal domain VIT1 PF01988.14 EEQ72733.1 - 7.3e-50 169.3 5.1 8.6e-50 169.1 3.5 1.0 1 0 0 1 1 1 1 VIT family Abhydrolase_9_N PF15420.1 EEQ72733.1 - 2.2 7.9 5.7 6.2 6.5 3.9 1.8 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus MadL PF03817.8 EEQ72733.1 - 6.6 6.6 12.0 0.17 11.7 3.6 1.9 2 1 0 2 2 2 0 Malonate transporter MadL subunit TT_ORF2 PF02957.10 EEQ72734.1 - 0.0033 18.1 1.6 0.0037 17.9 1.1 1.1 1 0 0 1 1 1 1 TT viral ORF2 DUF1180 PF06679.7 EEQ72734.1 - 0.89 9.4 3.6 0.94 9.3 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4106 PF13388.1 EEQ72734.1 - 1.4 7.8 6.2 1.4 7.8 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Herpes_DNAp_acc PF04929.7 EEQ72734.1 - 3.2 6.6 5.1 3.5 6.4 3.6 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor VPS9 PF02204.13 EEQ72736.1 - 1.1e-29 102.4 0.0 1.9e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EEQ72736.1 - 3.6e-10 39.1 0.5 1.6e-08 33.8 0.0 2.8 3 0 0 3 3 3 1 CUE domain Asn_synthase PF00733.16 EEQ72737.1 - 8.6e-52 176.1 0.0 1.1e-51 175.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EEQ72737.1 - 3.3e-07 30.0 0.0 3.9e-06 26.6 0.0 2.4 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EEQ72737.1 - 0.0059 16.5 0.0 0.023 14.6 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EEQ72737.1 - 0.056 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Aluminium induced protein zf-RING_2 PF13639.1 EEQ72739.1 - 4.1e-15 55.3 6.8 6.2e-15 54.7 4.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EEQ72739.1 - 2.6e-08 33.8 2.5 5.2e-08 32.8 1.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EEQ72739.1 - 3.6e-08 32.9 3.9 6.2e-08 32.1 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ72739.1 - 9.2e-07 28.4 4.0 1.5e-06 27.8 2.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEQ72739.1 - 1.3e-06 28.3 5.4 2.1e-06 27.6 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ72739.1 - 1e-05 25.0 2.4 1.6e-05 24.4 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEQ72739.1 - 0.00059 19.6 2.9 0.0013 18.4 2.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EEQ72739.1 - 0.022 14.3 5.7 0.038 13.5 3.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EEQ72739.1 - 0.036 14.0 3.7 0.11 12.4 2.6 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 EEQ72739.1 - 0.036 13.7 5.7 0.072 12.7 3.9 1.5 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.2 EEQ72739.1 - 0.048 13.7 5.6 0.084 12.9 3.9 1.4 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 EEQ72739.1 - 0.13 12.1 5.0 0.27 11.1 3.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EEQ72739.1 - 0.14 11.8 2.1 0.35 10.6 1.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_1 PF14446.1 EEQ72739.1 - 1.3 8.8 7.0 5.4 6.8 4.8 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 DUF3844 PF12955.2 EEQ72740.1 - 9.4e-41 138.0 3.5 1.7e-40 137.2 2.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 EEQ72740.1 - 0.73 10.0 7.1 3 8.0 4.9 2.0 1 1 0 1 1 1 0 EGF-like domain Abhydrolase_6 PF12697.2 EEQ72741.1 - 2.7e-06 27.4 0.2 1.2e-05 25.2 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ72741.1 - 0.0037 17.0 0.0 0.0066 16.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioredoxin_4 PF13462.1 EEQ72743.1 - 5.2e-08 33.0 0.0 9.8e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin DUF2454 PF10521.4 EEQ72743.1 - 0.059 12.3 0.1 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2454) DSBA PF01323.15 EEQ72743.1 - 0.07 12.6 0.2 0.74 9.3 0.0 2.4 2 1 0 2 2 2 0 DSBA-like thioredoxin domain CKS PF01111.14 EEQ72744.1 - 5.3e-36 122.2 1.7 5.4e-36 122.2 0.5 1.5 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit APC_15aa PF05972.6 EEQ72744.1 - 0.63 10.1 8.7 5.3 7.2 0.7 3.5 3 0 0 3 3 3 0 APC 15 residue motif Bromodomain PF00439.20 EEQ72745.1 - 2.7e-31 107.3 1.5 7.9e-15 54.5 0.1 3.2 3 0 0 3 3 3 2 Bromodomain SpoVG PF04026.7 EEQ72745.1 - 0.076 13.0 0.1 2.8 8.0 0.0 2.7 2 1 0 2 2 2 0 SpoVG Anophelin PF10731.4 EEQ72745.1 - 0.39 10.8 3.3 0.83 9.7 2.3 1.5 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito HSP70 PF00012.15 EEQ72746.1 - 2.3e-226 752.3 5.5 2.6e-226 752.2 3.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEQ72746.1 - 1.1e-16 60.4 0.1 1.1e-15 57.1 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EEQ72746.1 - 5.2e-05 22.9 0.0 0.00015 21.4 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 EEQ72746.1 - 0.031 13.1 0.4 0.15 10.8 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain MRC1 PF09444.5 EEQ72746.1 - 0.064 13.5 2.9 0.1 12.8 1.1 2.0 2 0 0 2 2 2 0 MRC1-like domain Flagellin_N PF00669.15 EEQ72746.1 - 0.085 12.6 2.1 0.21 11.3 1.4 1.7 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region FtsA PF14450.1 EEQ72746.1 - 3.2 7.6 8.4 27 4.6 0.0 4.1 2 1 0 2 2 2 0 Cell division protein FtsA RRF PF01765.14 EEQ72749.1 - 2.3e-28 98.7 3.0 1.5e-19 70.1 3.5 2.2 1 1 1 2 2 2 2 Ribosome recycling factor Senescence PF06911.7 EEQ72749.1 - 0.0038 16.9 2.1 0.0062 16.2 1.5 1.3 1 0 0 1 1 1 1 Senescence-associated protein DUF3391 PF11871.3 EEQ72749.1 - 0.82 9.8 5.9 23 5.1 4.0 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) DUF1664 PF07889.7 EEQ72749.1 - 1.5 8.6 5.5 3.3 7.5 3.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) APC_CDC26 PF10471.4 EEQ72751.1 - 3.3e-25 88.6 0.6 4.4e-25 88.2 0.4 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 Spc7_N PF15402.1 EEQ72751.1 - 0.034 12.1 0.2 0.044 11.7 0.2 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Zn_clus PF00172.13 EEQ72752.1 - 7.2e-06 25.8 9.2 1.3e-05 25.0 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEQ72752.1 - 0.00044 19.2 0.8 0.28 10.0 0.1 3.0 2 1 1 3 3 3 2 Fungal specific transcription factor domain DUF59 PF01883.14 EEQ72754.1 - 3.9e-07 29.9 0.0 7.9e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF59 GTP_EFTU PF00009.22 EEQ72755.1 - 1.2e-41 142.2 0.0 1.8e-41 141.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EEQ72755.1 - 5.6e-26 90.4 0.0 1.6e-25 88.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EEQ72755.1 - 1.5e-18 66.4 0.0 3.5e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EEQ72755.1 - 2.1e-08 34.1 0.0 6.3e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EEQ72755.1 - 3.3e-07 30.0 0.2 9.9e-07 28.5 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EEQ72755.1 - 0.00026 20.9 0.0 0.00048 20.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEQ72755.1 - 0.00088 19.7 0.0 0.0021 18.5 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Thiolase_N PF00108.18 EEQ72756.1 - 1.3e-99 332.4 0.2 1.8e-99 331.9 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EEQ72756.1 - 1e-42 144.4 2.2 2.3e-42 143.3 1.5 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EEQ72756.1 - 4.6e-06 26.3 1.4 1.1e-05 25.0 1.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EEQ72756.1 - 0.048 13.3 3.3 1 9.0 0.1 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Zip PF02535.17 EEQ72759.1 - 7e-48 163.2 6.5 9.3e-48 162.8 4.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2401 PF10287.4 EEQ72760.1 - 2.2e-89 298.9 0.0 3.2e-89 298.4 0.0 1.2 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EEQ72760.1 - 2.1e-05 24.5 0.1 0.00012 22.2 0.0 2.2 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) Atg14 PF10186.4 EEQ72762.1 - 4.5e-80 268.8 2.1 3e-53 180.7 0.0 2.1 1 1 1 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 DUF4654 PF15547.1 EEQ72764.1 - 0.24 11.7 5.3 0.28 11.4 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4654) LMBR1 PF04791.11 EEQ72765.1 - 6.9e-17 61.1 9.5 3.6e-16 58.8 1.6 2.2 1 1 1 2 2 2 2 LMBR1-like membrane protein DUF3611 PF12263.3 EEQ72765.1 - 0.18 11.2 0.1 0.18 11.2 0.1 3.8 4 1 1 5 5 5 0 Protein of unknown function (DUF3611) CPSF_A PF03178.10 EEQ72766.1 - 2.3e-103 345.6 0.0 6.1e-102 340.9 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EEQ72766.1 - 8.3e-05 20.9 0.0 0.022 12.9 0.0 2.3 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term AAA PF00004.24 EEQ72769.1 - 2.2e-49 167.0 0.0 6.3e-42 142.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EEQ72769.1 - 3.5e-08 33.0 0.0 7.5e-06 25.4 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 EEQ72769.1 - 3.3e-07 30.4 0.0 2.4e-05 24.3 0.0 3.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 EEQ72769.1 - 1.2e-05 25.2 0.0 3.2e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Bromodomain PF00439.20 EEQ72769.1 - 1.5e-05 24.8 0.0 4e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Bromodomain AAA_5 PF07728.9 EEQ72769.1 - 3.9e-05 23.4 0.0 0.0009 18.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 EEQ72769.1 - 7.3e-05 22.8 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.1 EEQ72769.1 - 9e-05 22.6 0.1 0.0023 18.0 0.0 2.9 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EEQ72769.1 - 0.00094 19.3 0.0 0.0037 17.4 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 EEQ72769.1 - 0.0012 18.7 0.0 0.011 15.5 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EEQ72769.1 - 0.0013 18.1 0.0 0.0041 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EEQ72769.1 - 0.0078 15.3 0.0 0.077 12.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 EEQ72769.1 - 0.01 14.5 0.0 0.019 13.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_33 PF13671.1 EEQ72769.1 - 0.011 15.6 0.9 0.029 14.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EEQ72769.1 - 0.013 15.1 0.0 0.16 11.5 0.0 2.5 2 1 0 2 2 2 0 NACHT domain AAA_17 PF13207.1 EEQ72769.1 - 0.017 15.9 0.0 0.017 15.9 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.1 EEQ72769.1 - 0.025 14.3 0.0 0.025 14.3 0.0 4.3 5 0 0 5 5 4 0 Part of AAA domain Sigma54_activat PF00158.21 EEQ72769.1 - 0.029 13.8 0.0 2.2 7.7 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain RuvB_N PF05496.7 EEQ72769.1 - 0.034 13.2 0.0 0.11 11.5 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 EEQ72769.1 - 0.068 12.7 0.0 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EEQ72769.1 - 0.078 12.1 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 EEQ72769.1 - 0.083 11.7 0.0 0.41 9.4 0.0 2.0 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Torsin PF06309.6 EEQ72769.1 - 0.36 10.7 0.0 1.4 8.8 0.0 1.9 2 0 0 2 2 2 0 Torsin Sec66 PF09802.4 EEQ72770.1 - 2.1e-82 275.1 0.2 2.5e-82 274.9 0.2 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 ABC_ATPase PF09818.4 EEQ72770.1 - 0.051 12.1 0.1 0.061 11.8 0.1 1.0 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Adeno_E1B_19K PF01691.11 EEQ72770.1 - 0.14 11.4 0.3 0.33 10.2 0.2 1.6 1 1 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen PPR_2 PF13041.1 EEQ72771.1 - 4.5e-11 42.5 0.9 0.051 13.5 0.0 5.8 6 1 1 7 7 7 3 PPR repeat family PPR_3 PF13812.1 EEQ72771.1 - 4.5e-09 35.8 1.8 0.03 14.5 0.0 6.1 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR PF01535.15 EEQ72771.1 - 0.012 15.4 4.1 0.17 11.9 0.0 4.0 5 0 0 5 5 5 0 PPR repeat DUF4111 PF13427.1 EEQ72771.1 - 0.044 13.6 0.1 0.12 12.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) Metal_resist PF13801.1 EEQ72771.1 - 0.054 13.4 0.2 0.21 11.5 0.2 2.1 1 0 0 1 1 1 0 Heavy-metal resistance PPR_1 PF12854.2 EEQ72771.1 - 0.37 10.3 3.9 0.29 10.6 0.1 2.7 3 0 0 3 3 3 0 PPR repeat ORC3_N PF07034.6 EEQ72772.1 - 4.1e-38 131.1 0.0 3.4e-37 128.1 0.0 2.0 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus HEAT_2 PF13646.1 EEQ72773.1 - 0.0012 19.0 0.3 0.0012 19.0 0.2 2.0 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.17 EEQ72773.1 - 0.008 16.1 0.2 6.1 7.1 0.0 2.8 2 0 0 2 2 2 2 HEAT repeat Nop14 PF04147.7 EEQ72774.1 - 4e-287 954.6 30.9 4.7e-287 954.4 21.4 1.0 1 0 0 1 1 1 1 Nop14-like family Noc2 PF03715.8 EEQ72774.1 - 0.0064 15.3 0.0 0.014 14.2 0.0 1.5 1 0 0 1 1 1 1 Noc2p family COesterase PF00135.23 EEQ72775.1 - 1.4e-92 311.1 0.1 1.8e-92 310.8 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEQ72775.1 - 1.7e-08 34.3 0.0 3.3e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEQ72775.1 - 0.0023 17.1 0.1 0.0035 16.5 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Cupin_8 PF13621.1 EEQ72776.1 - 5.6e-43 147.2 0.0 8.3e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.9 EEQ72776.1 - 1.7e-16 60.3 0.0 2.6e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 EEQ72776.1 - 4e-11 42.5 22.1 0.0019 17.8 0.2 6.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.1 EEQ72776.1 - 5.5e-10 39.1 9.7 2.2e-05 24.4 0.0 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.1 EEQ72776.1 - 8.5e-08 31.9 4.2 0.00096 19.0 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Cupin_4 PF08007.7 EEQ72776.1 - 7.8e-06 25.3 0.0 1.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_1 PF01344.20 EEQ72776.1 - 6 6.5 7.4 26 4.4 0.0 4.3 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.1 EEQ72776.1 - 6.9 7.0 11.5 0.85 9.9 0.4 4.3 2 2 2 4 4 4 0 Kelch motif WD40 PF00400.27 EEQ72777.1 - 3.6e-06 26.6 0.9 0.0014 18.4 0.0 4.2 5 0 0 5 5 5 1 WD domain, G-beta repeat CNH PF00780.17 EEQ72777.1 - 0.00011 21.7 0.1 0.57 9.5 0.0 3.0 2 1 0 2 2 2 2 CNH domain Coatomer_WDAD PF04053.9 EEQ72777.1 - 0.0031 16.3 0.0 0.011 14.5 0.0 1.9 3 0 0 3 3 3 1 Coatomer WD associated region CPSF_A PF03178.10 EEQ72777.1 - 0.016 14.2 0.1 0.65 9.0 0.0 2.6 2 1 0 2 2 2 0 CPSF A subunit region Hira PF07569.6 EEQ72777.1 - 0.029 13.6 0.0 0.09 11.9 0.0 1.8 2 0 0 2 2 2 0 TUP1-like enhancer of split Zn_clus PF00172.13 EEQ72779.1 - 1.4e-08 34.5 8.8 2.3e-08 33.7 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEQ72779.1 - 0.0003 19.5 0.6 0.00051 18.7 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain nsp8 PF08717.5 EEQ72780.1 - 0.071 12.7 0.1 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 nsp8 replicase MFS_1 PF07690.11 EEQ72781.1 - 8.5e-24 83.9 37.3 1.3e-23 83.3 25.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Met_10 PF02475.11 EEQ72782.1 - 0.00012 21.7 0.0 0.00023 20.8 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein EF-hand_6 PF13405.1 EEQ72783.1 - 1.7e-09 36.7 0.1 0.0042 16.8 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EEQ72783.1 - 0.0002 20.4 0.0 0.00074 18.6 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EEQ72783.1 - 0.00042 20.3 1.8 0.015 15.4 0.1 2.9 2 2 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 EEQ72783.1 - 0.097 12.2 0.0 0.18 11.4 0.0 1.6 1 1 0 1 1 1 0 EF-hand domain pair DUF342 PF03961.8 EEQ72784.1 - 1.2 7.4 5.6 8.3 4.7 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF342) OB_NTP_bind PF07717.11 EEQ72785.1 - 6.8e-26 90.3 0.0 1.5e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EEQ72785.1 - 1e-24 86.5 0.1 4.4e-24 84.4 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEQ72785.1 - 6.7e-11 41.9 0.0 1.7e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEQ72785.1 - 2.3e-07 30.4 0.2 4.7e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEQ72785.1 - 8.8e-06 25.8 0.1 5.2e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EEQ72785.1 - 0.00045 19.7 0.2 0.0012 18.3 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 EEQ72785.1 - 0.00051 19.8 0.1 0.001 18.8 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.10 EEQ72785.1 - 0.0022 17.8 0.0 0.66 9.7 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit T2SE PF00437.15 EEQ72785.1 - 0.011 14.6 0.0 0.024 13.5 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 EEQ72785.1 - 0.023 14.6 0.0 0.21 11.5 0.0 2.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 EEQ72785.1 - 0.13 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRMT5 PF05185.11 EEQ72786.1 - 1.8e-162 541.3 0.0 2.4e-162 540.9 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase GDPD PF03009.12 EEQ72787.1 - 6.2e-52 176.6 0.0 6.9e-43 146.9 0.0 2.3 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EEQ72787.1 - 2.8e-34 117.3 0.1 1.5e-12 47.6 0.2 4.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEQ72787.1 - 4.9e-33 112.9 0.9 2.3e-10 40.7 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EEQ72787.1 - 1.6e-28 97.0 3.3 7.5e-05 22.3 0.0 6.9 6 0 0 6 6 6 5 Ankyrin repeat SPX PF03105.14 EEQ72787.1 - 5e-28 98.6 3.8 1.4e-14 54.5 1.9 3.3 1 1 1 2 2 2 2 SPX domain Ank_5 PF13857.1 EEQ72787.1 - 9.9e-22 76.4 4.0 1.2e-07 31.7 0.0 6.2 1 1 5 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ72787.1 - 3.1e-18 64.0 2.1 0.004 17.2 0.0 7.2 6 0 0 6 6 6 4 Ankyrin repeat UNC45-central PF11701.3 EEQ72789.1 - 1.3e-41 141.9 0.2 3.9e-41 140.3 0.1 1.9 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central Atx10homo_assoc PF09759.4 EEQ72789.1 - 0.0028 17.3 0.0 0.11 12.2 0.0 2.8 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 EEQ72789.1 - 0.0028 17.4 11.4 17 5.4 0.0 6.7 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat RICTOR_N PF14664.1 EEQ72789.1 - 0.018 13.6 1.1 0.46 9.0 0.1 2.8 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term TPR_11 PF13414.1 EEQ72789.1 - 0.048 13.3 0.1 0.14 11.7 0.0 1.8 1 0 0 1 1 1 0 TPR repeat DHHA1 PF02272.14 EEQ72789.1 - 0.41 10.3 4.6 4.2 7.1 3.4 2.4 2 0 0 2 2 2 0 DHHA1 domain TPR_14 PF13428.1 EEQ72789.1 - 2.4 9.0 6.3 1.5 9.6 0.6 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat Tfb4 PF03850.9 EEQ72790.1 - 2.2e-109 365.0 0.0 2.9e-109 364.6 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 EEQ72790.1 - 0.016 15.3 0.1 0.05 13.6 0.1 1.7 1 1 0 1 1 1 0 von Willebrand factor type A domain zf-C2HC5 PF06221.8 EEQ72790.1 - 0.3 10.8 3.3 0.66 9.7 2.3 1.5 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Asparaginase_2 PF01112.13 EEQ72791.1 - 1.1e-25 90.0 8.0 1e-12 47.4 2.6 2.3 2 0 0 2 2 2 2 Asparaginase Actin PF00022.14 EEQ72792.1 - 2.6e-89 299.4 0.0 3.9e-89 298.8 0.0 1.2 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EEQ72792.1 - 0.00023 19.9 0.1 0.01 14.4 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DUF1399 PF07173.7 EEQ72793.1 - 1.2e-19 70.9 9.0 3.7e-17 62.9 0.1 3.6 3 0 0 3 3 3 3 Protein of unknown function (DUF1399) tRNA_U5-meth_tr PF05958.6 EEQ72794.1 - 7.5e-14 51.1 0.0 3.9e-06 25.7 0.0 2.6 3 0 0 3 3 3 2 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EEQ72794.1 - 0.00017 21.2 0.0 0.00034 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 EEQ72794.1 - 0.0048 16.6 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 TRAM domain Methyltransf_26 PF13659.1 EEQ72794.1 - 0.014 15.3 0.1 0.044 13.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 EEQ72794.1 - 0.031 13.3 0.0 0.21 10.6 0.0 2.3 2 1 0 2 2 2 0 Putative methyltransferase Methyltransf_15 PF09445.5 EEQ72794.1 - 0.046 13.2 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 EEQ72794.1 - 0.054 14.0 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S5_C PF03719.10 EEQ72795.1 - 8.7e-21 72.9 0.0 1.7e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EEQ72795.1 - 8.6e-10 38.2 2.2 1.1e-09 37.8 0.3 2.0 1 1 1 2 2 2 1 Ribosomal protein S5, N-terminal domain HhH-GPD PF00730.20 EEQ72795.1 - 0.013 15.7 0.1 7.4 6.8 0.0 2.6 2 0 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein DUF3500 PF12006.3 EEQ72795.1 - 0.036 13.0 0.0 0.052 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) Pkinase PF00069.20 EEQ72797.1 - 1.3e-70 237.5 0.0 2.1e-70 236.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ72797.1 - 2e-30 105.7 0.0 4.5e-22 78.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEQ72797.1 - 3.1e-05 23.0 0.0 0.42 9.5 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 EEQ72797.1 - 0.042 12.8 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family His_Phos_2 PF00328.17 EEQ72799.1 - 1.8e-08 34.1 0.0 5.4e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TRF PF08558.5 EEQ72800.1 - 3.8e-89 298.1 0.8 6.6e-89 297.3 0.6 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EEQ72800.1 - 2e-05 24.5 0.1 3.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain AAA_23 PF13476.1 EEQ72800.1 - 0.26 11.6 22.5 0.19 12.0 11.5 2.8 2 1 0 2 2 2 0 AAA domain Zip PF02535.17 EEQ72800.1 - 0.92 8.4 6.5 2.2 7.2 4.5 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter FAM60A PF15396.1 EEQ72800.1 - 3.2 7.4 15.9 13 5.4 11.0 2.2 1 0 0 1 1 1 0 Protein Family FAM60A TFIID_30kDa PF03540.8 EEQ72801.1 - 7.9e-24 83.2 0.1 1.2e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.1 EEQ72801.1 - 1.2 9.6 4.7 7 7.1 3.2 2.3 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 TFIIA PF03153.8 EEQ72801.1 - 4.8 6.9 20.1 6.9 6.4 14.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.2 EEQ72801.1 - 6.7 4.2 13.3 8.7 3.8 9.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ribosomal_S19 PF00203.16 EEQ72802.1 - 1e-21 76.3 0.0 1.4e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 IPK PF03770.11 EEQ72803.1 - 5.4e-61 205.6 0.0 8.2e-61 205.0 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Arb1 PF09692.5 EEQ72804.1 - 2.1e-151 504.2 0.0 2.6e-151 503.9 0.0 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 ADH_zinc_N PF00107.21 EEQ72805.1 - 3.1e-28 97.9 0.1 5.2e-28 97.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEQ72805.1 - 1.6e-22 80.7 0.0 2.9e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEQ72805.1 - 2.2e-10 40.2 0.0 4.7e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Clp1 PF06807.9 EEQ72809.1 - 1.4e-16 60.8 0.0 2.6e-09 37.1 0.0 3.0 1 1 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 Vma12 PF11712.3 EEQ72809.1 - 0.17 11.5 0.4 0.68 9.6 0.1 1.9 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Rho_GDI PF02115.12 EEQ72811.1 - 9e-58 194.9 0.1 9.9e-58 194.8 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Metallophos PF00149.23 EEQ72812.1 - 7e-42 143.0 0.7 9.1e-42 142.7 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-CCHC PF00098.18 EEQ72813.1 - 2.3e-05 24.0 0.8 4.8e-05 23.0 0.6 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EEQ72813.1 - 0.041 13.6 0.6 0.11 12.2 0.4 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EEQ72813.1 - 0.043 13.4 0.2 0.08 12.6 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle APH PF01636.18 EEQ72814.1 - 0.049 13.3 0.6 0.24 11.1 0.3 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family UMPH-1 PF05822.7 EEQ72814.1 - 0.14 11.4 0.2 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) Lin-8 PF03353.10 EEQ72815.1 - 5.3 6.2 7.9 6.2 6.0 5.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Adaptin_N PF01602.15 EEQ72816.1 - 5.5e-103 345.0 0.0 7.1e-103 344.7 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EEQ72816.1 - 1.5e-10 41.1 1.6 5.2e-05 23.4 0.0 4.5 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EEQ72816.1 - 2.6e-07 30.1 0.0 0.037 14.1 0.0 4.6 5 0 0 5 5 3 2 HEAT repeat Cohesin_HEAT PF12765.2 EEQ72816.1 - 0.0037 17.1 0.8 2.9 7.9 0.0 4.5 5 0 0 5 5 5 1 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.1 EEQ72816.1 - 0.019 15.4 6.6 1.6 9.3 0.0 5.1 5 1 1 6 6 6 0 HEAT-like repeat Arm PF00514.18 EEQ72816.1 - 0.046 13.5 2.2 1.2 9.0 0.1 3.9 3 2 1 4 4 4 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 EEQ72816.1 - 0.1 12.4 0.1 14 5.5 0.0 2.8 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 SDA1 PF05285.7 EEQ72816.1 - 0.7 9.1 19.9 1.2 8.3 13.8 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EEQ72816.1 - 1.9 6.3 23.8 3.3 5.4 16.5 1.3 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EEQ72816.1 - 2 6.8 21.3 2.8 6.3 14.8 1.1 1 0 0 1 1 1 0 Daxx Family DUF2890 PF11081.3 EEQ72816.1 - 2.1 8.3 16.6 4.3 7.3 11.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) BUD22 PF09073.5 EEQ72816.1 - 6.9 5.6 19.4 10 5.0 13.5 1.1 1 0 0 1 1 1 0 BUD22 Nuf2 PF03800.9 EEQ72818.1 - 1.6e-43 148.1 0.1 1.6e-43 148.1 0.1 2.5 3 1 0 3 3 3 1 Nuf2 family Reo_sigmaC PF04582.7 EEQ72818.1 - 1.2 8.2 3.9 1 8.4 1.2 1.8 1 1 0 2 2 2 0 Reovirus sigma C capsid protein IF-2B PF01008.12 EEQ72819.1 - 2.6e-46 157.8 0.0 1.3e-45 155.5 0.0 1.8 1 1 0 1 1 1 1 Initiation factor 2 subunit family TPR_5 PF12688.2 EEQ72819.1 - 0.092 12.7 0.1 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Tetratrico peptide repeat DUF1681 PF07933.9 EEQ72820.1 - 2.7e-60 202.5 0.0 3.7e-60 202.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Thioredoxin PF00085.15 EEQ72823.1 - 1.5e-27 95.2 0.1 2.2e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EEQ72823.1 - 5.4e-08 33.0 0.5 6.5e-07 29.5 0.3 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EEQ72823.1 - 1.1e-05 25.3 0.0 0.00016 21.7 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EEQ72823.1 - 5.5e-05 22.7 0.0 8.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 EEQ72823.1 - 0.005 16.3 0.3 0.043 13.3 0.2 2.1 1 1 1 2 2 2 1 Redoxin Glutaredoxin PF00462.19 EEQ72823.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin AhpC-TSA PF00578.16 EEQ72823.1 - 0.15 11.7 0.2 0.41 10.3 0.1 1.7 1 1 0 1 1 1 0 AhpC/TSA family OTU PF02338.14 EEQ72824.1 - 1.3e-13 51.5 0.1 4.4e-13 49.8 0.0 1.9 1 1 0 1 1 1 1 OTU-like cysteine protease DAO PF01266.19 EEQ72825.1 - 4.2e-24 85.1 0.1 7.2e-24 84.3 0.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase DUF1188 PF06690.6 EEQ72825.1 - 0.035 13.2 0.0 0.81 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) NAD_binding_8 PF13450.1 EEQ72825.1 - 0.062 13.3 1.3 0.1 12.6 0.1 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Saccharop_dh PF03435.13 EEQ72825.1 - 0.094 11.6 0.3 0.2 10.6 0.1 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase FAD_binding_4 PF01565.18 EEQ72826.1 - 3.1e-26 91.5 1.7 5.7e-26 90.6 1.2 1.5 1 0 0 1 1 1 1 FAD binding domain COPI_assoc PF08507.5 EEQ72827.1 - 9.4e-45 151.6 3.5 1e-44 151.5 2.4 1.0 1 0 0 1 1 1 1 COPI associated protein DUF3784 PF12650.2 EEQ72827.1 - 8 6.4 8.7 2 8.3 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) Bax1-I PF01027.15 EEQ72827.1 - 9.3 5.7 10.9 14 5.2 7.2 1.3 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 GATA PF00320.22 EEQ72829.1 - 3.8e-29 99.7 18.1 8.4e-16 57.0 2.8 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EEQ72829.1 - 7.7e-05 21.9 2.4 0.0098 15.1 0.1 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.13 EEQ72829.1 - 0.0084 15.8 1.6 0.62 9.8 0.0 2.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.5 EEQ72829.1 - 0.11 12.4 3.0 6.3 6.8 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.2 EEQ72829.1 - 0.3 10.9 13.6 2.3 8.1 3.2 3.2 1 1 1 2 2 2 0 Double zinc ribbon Auto_anti-p27 PF06677.7 EEQ72829.1 - 0.44 10.3 4.4 1.3 8.8 0.2 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.12 EEQ72829.1 - 0.6 9.7 5.0 3 7.5 0.3 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 TFIIS_C PF01096.13 EEQ72829.1 - 6.6 6.4 7.1 4.2 7.0 0.1 3.2 2 1 1 3 3 3 0 Transcription factor S-II (TFIIS) adh_short PF00106.20 EEQ72830.1 - 2.7e-11 43.6 0.1 4.2e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EEQ72830.1 - 0.017 14.5 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.5 EEQ72830.1 - 0.065 12.8 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 KR domain adh_short_C2 PF13561.1 EEQ72830.1 - 0.075 12.7 0.0 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase AAA_10 PF12846.2 EEQ72831.1 - 0.074 12.4 0.1 0.16 11.3 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain adh_short PF00106.20 EEQ72833.1 - 1e-33 116.6 0.0 1.4e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ72833.1 - 9.8e-16 58.2 0.0 1.3e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ72833.1 - 1.5e-12 47.5 0.0 2.3e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EEQ72833.1 - 0.0033 16.3 0.1 0.0076 15.1 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Lin0512_fam PF09585.5 EEQ72833.1 - 0.052 13.1 0.1 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical protein (Lin0512_fam) Eno-Rase_NADH_b PF12242.3 EEQ72833.1 - 0.082 12.7 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Cofilin_ADF PF00241.15 EEQ72834.1 - 5.2e-10 39.2 0.0 6e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MoCF_biosynth PF00994.19 EEQ72835.1 - 2.2e-35 121.1 0.0 3.7e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain Ras PF00071.17 EEQ72837.1 - 6.5e-59 197.9 0.2 7.7e-59 197.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ72837.1 - 4.9e-19 68.9 0.0 7.1e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ72837.1 - 1.1e-08 34.5 0.0 1.3e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEQ72837.1 - 1.2e-08 34.6 0.1 6.7e-08 32.1 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEQ72837.1 - 0.0018 18.2 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEQ72837.1 - 0.0028 16.9 0.1 0.005 16.1 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EEQ72837.1 - 0.0051 15.9 0.1 0.0071 15.5 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EEQ72837.1 - 0.053 12.7 0.2 0.17 11.0 0.1 1.6 2 1 0 2 2 2 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EEQ72837.1 - 0.056 12.8 0.7 0.71 9.2 0.1 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.12 EEQ72837.1 - 0.26 10.8 2.0 2.8 7.4 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DUF3435 PF11917.3 EEQ72838.1 - 9.6e-80 268.3 0.0 1.3e-59 201.9 0.0 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) zf-C2H2 PF00096.21 EEQ72838.1 - 0.13 12.6 0.4 0.43 11.0 0.3 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ72838.1 - 0.18 12.2 0.8 0.7 10.3 0.6 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger DUF3435 PF11917.3 EEQ72839.1 - 1.6e-102 343.4 0.1 2.2e-102 342.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) FAD_binding_3 PF01494.14 EEQ72841.1 - 4.4e-11 42.4 0.1 2.2e-10 40.1 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEQ72841.1 - 2.1e-07 30.1 0.1 9e-05 21.5 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EEQ72841.1 - 0.00085 18.0 0.6 0.0075 14.9 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.1 EEQ72841.1 - 0.0012 18.8 0.0 0.0066 16.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain zf-ribbon_3 PF13248.1 EEQ72843.1 - 0.00031 19.8 1.3 0.00031 19.8 0.9 4.0 4 1 0 4 4 4 2 zinc-ribbon domain FYVE_2 PF02318.11 EEQ72843.1 - 0.00056 19.7 21.9 0.33 10.8 1.1 3.3 3 0 0 3 3 3 3 FYVE-type zinc finger Siva PF05458.7 EEQ72843.1 - 3.7 7.0 27.9 2.4 7.7 3.1 3.3 2 1 1 3 3 3 0 Cd27 binding protein (Siva) DUF2490 PF10677.4 EEQ72845.1 - 0.11 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2490) Cupredoxin_1 PF13473.1 EEQ72848.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Cupredoxin-like domain DUF1517 PF07466.6 EEQ72848.1 - 9 5.1 7.4 13 4.6 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) 2OG-FeII_Oxy PF03171.15 EEQ72849.1 - 8.8e-15 54.8 0.0 1.5e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EEQ72849.1 - 3.3e-12 46.9 0.0 5.4e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal UPF0086 PF01868.11 EEQ72850.1 - 7.3e-30 102.4 0.2 1.1e-29 101.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 tRNA_int_endo PF01974.12 EEQ72851.1 - 1.1e-14 53.9 0.0 2e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DUF2361 PF10153.4 EEQ72851.1 - 0.58 10.3 3.9 0.87 9.7 2.7 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) PAXNEB PF05625.6 EEQ72852.1 - 8.9e-121 403.1 0.0 9.9e-121 402.9 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein RNA_pol_Rpb8 PF03870.10 EEQ72853.1 - 4.8e-37 127.2 0.0 5.4e-37 127.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 NUDIX PF00293.23 EEQ72854.1 - 1.6e-08 34.2 0.0 2.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Fungal_trans_2 PF11951.3 EEQ72855.1 - 8.8e-08 31.1 5.6 1.6e-06 26.9 0.2 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ72855.1 - 8.5e-06 25.5 11.6 8.5e-06 25.5 8.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mucin PF01456.12 EEQ72856.1 - 1.5 8.5 14.4 2.2 8.0 10.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein LRR_9 PF14580.1 EEQ72857.1 - 8.6e-53 178.4 1.3 1.4e-52 177.8 0.0 1.7 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 EEQ72857.1 - 2.4e-11 43.0 13.6 7.1e-07 28.7 0.5 4.1 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEQ72857.1 - 1.4e-10 40.7 10.0 1.2e-06 28.1 1.3 2.9 2 1 1 3 3 3 2 Leucine rich repeat PHTB1_N PF14727.1 EEQ72857.1 - 0.033 13.1 0.1 0.047 12.6 0.1 1.1 1 0 0 1 1 1 0 PTHB1 N-terminus HTH_38 PF13936.1 EEQ72857.1 - 0.07 12.7 0.6 0.15 11.6 0.4 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain LRR_1 PF00560.28 EEQ72857.1 - 0.11 12.5 7.2 7.7 6.9 0.0 4.8 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_7 PF13504.1 EEQ72857.1 - 1.2 9.6 3.6 44 4.9 0.0 3.9 4 1 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 EEQ72857.1 - 5.6 7.3 5.2 33 4.9 0.2 3.7 3 1 1 4 4 4 0 Leucine Rich repeat GDA1_CD39 PF01150.12 EEQ72858.1 - 1.1e-99 333.9 0.0 1.5e-99 333.4 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Acyltransferase PF01553.16 EEQ72859.1 - 4.1e-05 23.0 0.0 9.5e-05 21.8 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase HTH_Crp_2 PF13545.1 EEQ72859.1 - 0.049 13.4 0.0 6.8 6.5 0.0 2.7 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Pantoate_ligase PF02569.10 EEQ72860.1 - 1.7e-81 273.0 0.0 1.6e-47 161.5 0.0 2.1 2 0 0 2 2 2 2 Pantoate-beta-alanine ligase DEAD PF00270.24 EEQ72861.1 - 8.1e-41 139.3 0.1 1.4e-40 138.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EEQ72861.1 - 5.5e-20 70.6 0.0 1.1e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EEQ72861.1 - 3.4e-19 68.4 0.0 8.4e-19 67.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ72861.1 - 0.0036 17.1 0.0 0.009 15.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit cEGF PF12662.2 EEQ72861.1 - 0.13 11.9 0.3 0.3 10.7 0.2 1.7 1 0 0 1 1 1 0 Complement Clr-like EGF-like WD40 PF00400.27 EEQ72862.1 - 3e-19 68.1 1.0 0.028 14.2 0.0 6.9 7 1 0 7 7 7 5 WD domain, G-beta repeat Kelch_2 PF07646.10 EEQ72862.1 - 0.12 12.1 0.0 0.74 9.6 0.0 2.2 2 0 0 2 2 2 0 Kelch motif Pyridox_oxase_2 PF12766.2 EEQ72863.1 - 3.2e-30 104.3 0.0 5.5e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CDC45 PF02724.9 EEQ72864.1 - 0.24 9.3 8.7 0.35 8.8 6.0 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF3439 PF11921.3 EEQ72864.1 - 1.8 8.3 20.4 0.47 10.2 10.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Spt5_N PF11942.3 EEQ72864.1 - 2.1 8.9 14.4 0.18 12.4 4.8 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal zf-C4_ClpX PF06689.8 EEQ72864.1 - 4.5 6.8 8.5 13 5.3 0.2 3.0 2 1 0 2 2 2 0 ClpX C4-type zinc finger DZR PF12773.2 EEQ72864.1 - 4.8 7.0 11.5 2.4 8.0 2.1 2.8 2 0 0 2 2 2 0 Double zinc ribbon C1_1 PF00130.17 EEQ72864.1 - 7.4 6.3 9.1 0.27 10.9 0.5 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RTP801_C PF07809.6 EEQ72865.1 - 0.00089 18.9 0.3 0.0011 18.5 0.2 1.2 1 0 0 1 1 1 1 RTP801 C-terminal region APH PF01636.18 EEQ72867.1 - 2.4e-08 34.0 0.0 3.5e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EEQ72867.1 - 0.0021 17.2 0.0 0.0076 15.4 0.0 1.8 2 0 0 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.15 EEQ72867.1 - 0.043 13.3 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.6 EEQ72867.1 - 0.048 12.2 0.0 0.088 11.4 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) DUF1785 PF08699.5 EEQ72868.1 - 7e-11 41.3 0.1 1.6e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) AAA PF00004.24 EEQ72871.1 - 5.5e-11 42.7 0.0 8.6e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEQ72871.1 - 0.00021 22.0 0.0 0.00037 21.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEQ72871.1 - 0.014 15.5 0.3 0.41 10.8 0.2 2.3 1 1 0 1 1 1 0 AAA domain Kinesin PF00225.18 EEQ72871.1 - 0.022 13.4 0.0 0.025 13.2 0.0 1.1 1 0 0 1 1 1 0 Kinesin motor domain AAA_18 PF13238.1 EEQ72871.1 - 0.035 14.4 0.0 0.057 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EEQ72871.1 - 0.12 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Peptidase_C12 PF01088.16 EEQ72877.1 - 8.3e-51 172.1 0.0 9.4e-51 172.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Ank_2 PF12796.2 EEQ72878.1 - 0.00018 21.7 0.0 0.00042 20.5 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEQ72878.1 - 0.00031 21.1 0.0 0.001 19.5 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EEQ72878.1 - 0.00046 19.8 0.6 0.0018 17.9 0.0 2.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 EEQ72878.1 - 0.037 14.2 0.1 0.23 11.8 0.0 2.3 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.1 EEQ72878.1 - 0.048 13.9 0.2 0.32 11.3 0.0 2.3 2 1 1 3 3 3 0 Ankyrin repeats (many copies) APH PF01636.18 EEQ72879.1 - 2.7e-12 46.9 0.0 1.2e-11 44.7 0.0 2.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family EcKinase PF02958.15 EEQ72879.1 - 0.00028 20.1 0.0 0.016 14.3 0.0 2.2 2 0 0 2 2 2 2 Ecdysteroid kinase Choline_kinase PF01633.15 EEQ72879.1 - 0.0025 17.4 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EEQ72879.1 - 0.017 13.7 0.0 0.25 9.9 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1679) F-box-like PF12937.2 EEQ72881.1 - 4.5e-07 29.4 0.1 9.6e-07 28.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like Acyl_transf_3 PF01757.17 EEQ72882.1 - 6.7e-10 38.3 1.4 8e-10 38.0 1.0 1.0 1 0 0 1 1 1 1 Acyltransferase family DUF1624 PF07786.7 EEQ72882.1 - 0.001 18.4 0.4 0.002 17.5 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1624) DUF3435 PF11917.3 EEQ72883.1 - 1.3e-57 195.3 1.9 1.7e-49 168.6 1.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3435) GAGA PF09237.6 EEQ72883.1 - 0.09 12.3 1.2 1.8 8.2 0.1 2.5 2 0 0 2 2 2 0 GAGA factor SBP_bac_11 PF13531.1 EEQ72887.1 - 0.0047 16.5 0.1 0.025 14.2 0.1 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF3034 PF11231.3 EEQ72887.1 - 0.091 12.1 0.0 0.25 10.6 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3034) eIF-5a PF01287.15 EEQ72889.1 - 0.0091 15.9 0.9 0.26 11.2 0.0 2.3 1 1 1 2 2 2 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Cep57_CLD_2 PF14197.1 EEQ72889.1 - 0.021 14.7 0.9 0.021 14.7 0.6 1.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 ASXH PF13919.1 EEQ72889.1 - 0.039 13.7 0.5 0.058 13.1 0.4 1.3 1 1 0 1 1 1 0 Asx homology domain Spc7 PF08317.6 EEQ72889.1 - 0.059 12.0 3.9 0.072 11.7 2.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FUSC PF04632.7 EEQ72889.1 - 0.21 9.9 0.5 0.21 9.9 0.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF342 PF03961.8 EEQ72889.1 - 0.23 9.8 1.4 0.29 9.4 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3486 PF11985.3 EEQ72889.1 - 0.45 10.5 3.7 3.4 7.6 2.5 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3486) DUF2508 PF10704.4 EEQ72889.1 - 0.51 10.5 5.5 0.31 11.2 0.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2508) CENP-Q PF13094.1 EEQ72889.1 - 1.1 9.2 4.8 1.3 9.0 0.4 2.0 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 EEQ72889.1 - 1.8 8.1 9.1 29 4.1 6.3 2.0 1 1 0 1 1 1 0 IncA protein DUF221 PF02714.10 EEQ72891.1 - 6.2e-114 380.2 18.4 6.2e-114 380.2 12.7 2.8 4 0 0 4 4 4 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 EEQ72891.1 - 3.8e-46 156.4 0.4 3.8e-46 156.4 0.2 3.3 5 0 0 5 5 5 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EEQ72891.1 - 1.4e-34 117.8 0.1 3.2e-33 113.4 0.1 2.7 3 0 0 3 3 3 1 Phosphate metabolism protein DUF4463 PF14703.1 EEQ72891.1 - 5.9e-19 68.3 0.2 1e-18 67.6 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) MCM PF00493.18 EEQ72892.1 - 5.4e-112 373.8 0.9 7.2e-91 304.4 0.1 2.4 1 1 1 2 2 2 2 MCM2/3/5 family MCM_N PF14551.1 EEQ72892.1 - 1.7e-18 67.2 1.8 4.4e-18 65.9 0.1 2.5 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEQ72892.1 - 6.4e-05 22.2 0.0 0.00024 20.3 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EEQ72892.1 - 0.0015 18.1 0.2 0.0078 15.8 0.0 2.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EEQ72892.1 - 0.035 13.5 0.0 0.099 12.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Helicase_C PF00271.26 EEQ72893.1 - 8.7e-05 22.3 0.0 0.00022 21.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UBA_4 PF14555.1 EEQ72894.1 - 1e-12 47.3 0.8 2.7e-12 46.0 0.6 1.8 1 0 0 1 1 1 1 UBA-like domain SET PF00856.23 EEQ72895.1 - 2.3e-13 50.7 0.1 7.4e-12 45.8 0.1 2.7 1 1 0 1 1 1 1 SET domain GATase_2 PF00310.16 EEQ72895.1 - 0.094 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II AMP-binding PF00501.23 EEQ72896.1 - 5.3e-93 311.6 0.0 6.6e-93 311.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ72896.1 - 3.6e-10 40.6 2.0 1e-09 39.1 0.4 2.5 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.20 EEQ72897.1 - 2e-56 191.0 0.0 3.2e-56 190.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ72897.1 - 1.2e-25 90.0 0.0 4.9e-25 88.0 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ72897.1 - 0.0021 17.0 0.0 0.0035 16.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF2052 PF09747.4 EEQ72900.1 - 1e-36 126.5 12.6 3.2e-36 124.9 8.8 1.7 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Spermine_synth PF01564.12 EEQ72901.1 - 8.2e-08 31.4 0.0 1.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 EEQ72901.1 - 0.0027 18.2 0.0 0.0055 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ72901.1 - 0.071 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Y_phosphatase3 PF13350.1 EEQ72902.1 - 3.8e-47 160.5 0.0 5.5e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EEQ72902.1 - 1.2e-15 57.3 1.6 2.1e-14 53.3 0.1 3.1 3 1 0 3 3 3 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EEQ72902.1 - 0.016 14.5 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EEQ72902.1 - 0.061 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.8 EEQ72902.1 - 0.08 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Peptidase_S9 PF00326.16 EEQ72906.1 - 1.8e-53 180.9 0.0 2.7e-53 180.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEQ72906.1 - 1.2e-09 38.0 0.0 2.4e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ72906.1 - 1.9e-07 31.1 0.0 5.3e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family PD40 PF07676.7 EEQ72906.1 - 2.4e-07 30.2 0.6 0.27 10.9 0.1 3.9 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat COesterase PF00135.23 EEQ72906.1 - 0.014 14.1 0.1 0.02 13.6 0.1 1.1 1 0 0 1 1 1 0 Carboxylesterase family DPPIV_N PF00930.16 EEQ72906.1 - 0.046 12.3 0.0 0.5 8.9 0.0 2.5 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S28 PF05577.7 EEQ72906.1 - 0.2 10.2 0.0 0.41 9.1 0.0 1.4 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DLIC PF05783.6 EEQ72907.1 - 1e-37 129.9 0.2 2.4e-34 118.8 0.0 3.0 3 0 0 3 3 3 3 Dynein light intermediate chain (DLIC) Myb_CC_LHEQLE PF14379.1 EEQ72907.1 - 0.17 11.5 2.3 0.38 10.3 1.6 1.5 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif RRM_1 PF00076.17 EEQ72908.1 - 2e-19 69.0 0.0 6.4e-19 67.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ72908.1 - 4.3e-12 45.8 0.0 1.3e-11 44.3 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ72908.1 - 6.7e-06 25.8 0.0 1.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MRI PF15325.1 EEQ72908.1 - 1.4 9.9 5.2 3.7 8.5 3.6 1.8 1 1 0 1 1 1 0 Modulator of retrovirus infection Peptidase_C12 PF01088.16 EEQ72908.1 - 6.1 5.9 6.1 9.5 5.3 4.2 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 WD40 PF00400.27 EEQ72909.1 - 3.3e-06 26.7 0.0 0.012 15.4 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat Septin PF00735.13 EEQ72910.1 - 5e-107 357.1 0.1 9.5e-107 356.1 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EEQ72910.1 - 7.5e-05 22.6 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EEQ72910.1 - 0.0012 18.6 5.1 0.25 11.1 0.0 2.9 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 EEQ72910.1 - 0.0025 17.0 0.3 0.0084 15.3 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EEQ72910.1 - 0.0041 16.5 0.0 0.12 11.8 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EEQ72910.1 - 0.024 15.1 0.6 0.062 13.7 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 EEQ72910.1 - 0.048 13.8 0.0 0.18 11.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EEQ72910.1 - 0.08 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AIG1 PF04548.11 EEQ72910.1 - 0.09 11.8 0.0 0.09 11.8 0.0 2.1 2 0 0 2 2 2 0 AIG1 family AAA_17 PF13207.1 EEQ72910.1 - 0.14 12.9 4.6 0.34 11.7 0.1 2.9 2 2 0 2 2 2 0 AAA domain FMN_bind PF04205.9 EEQ72910.1 - 0.16 12.1 0.5 0.52 10.5 0.0 2.0 2 0 0 2 2 2 0 FMN-binding domain ABC_tran PF00005.22 EEQ72910.1 - 0.22 11.8 1.4 1.2 9.4 0.0 2.5 2 1 0 2 2 2 0 ABC transporter Glyco_hydro_2_N PF02837.13 EEQ72911.1 - 4.3e-25 88.2 0.0 7.6e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EEQ72911.1 - 3.1e-12 46.0 0.1 7e-12 44.8 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EEQ72911.1 - 4.9e-06 26.9 0.0 2.2e-05 24.8 0.0 2.1 2 1 0 2 2 2 1 Glycosyl hydrolases family 2 CNH PF00780.17 EEQ72912.1 - 6.8e-81 271.6 0.0 1.1e-79 267.7 0.0 2.1 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 EEQ72912.1 - 1.9e-41 141.1 0.0 4.1e-41 140.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EEQ72912.1 - 3.1e-38 131.4 0.1 6.6e-38 130.3 0.1 1.6 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EEQ72912.1 - 4.5e-13 48.7 0.0 1e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ATP-synt_C PF00137.16 EEQ72913.1 - 2.4e-25 88.2 33.4 2.6e-15 56.0 6.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Pkinase PF00069.20 EEQ72914.1 - 3.1e-63 213.3 0.0 4.2e-63 212.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ72914.1 - 1.4e-34 119.3 0.0 2.3e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ72914.1 - 2.5e-05 24.1 0.3 0.11 12.2 0.2 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EEQ72914.1 - 0.0089 15.0 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Gly_transf_sug PF04488.10 EEQ72915.1 - 2e-11 44.1 0.0 3.7e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Glyco_hydro_43 PF04616.9 EEQ72917.1 - 1.2e-17 63.9 0.0 1.2e-16 60.6 0.0 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 43 PBP1_TM PF14812.1 EEQ72917.1 - 0.003 17.8 0.1 0.0058 16.9 0.1 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF912 PF06024.7 EEQ72917.1 - 0.19 11.8 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PYST-C1 PF09690.5 EEQ72917.1 - 1.7 8.3 8.3 3.5 7.3 5.8 1.4 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) Abhydrolase_1 PF00561.15 EEQ72918.1 - 8.4e-20 71.3 0.0 4.5e-18 65.6 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEQ72918.1 - 2.1e-11 44.1 2.7 5.9e-10 39.4 1.9 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EEQ72918.1 - 0.00032 20.2 0.0 0.00059 19.3 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Pex14_N PF04695.8 EEQ72918.1 - 0.71 9.9 12.3 1 9.4 0.3 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ThiF PF00899.16 EEQ72919.1 - 1.7e-35 121.7 0.0 3.5e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.13 EEQ72919.1 - 0.0099 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 EEQ72919.1 - 0.012 14.6 1.0 0.082 11.8 0.7 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase DAO PF01266.19 EEQ72919.1 - 0.012 14.5 0.4 0.11 11.3 0.1 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase ApbA PF02558.11 EEQ72919.1 - 0.014 14.8 0.1 0.025 14.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 EEQ72919.1 - 0.061 12.3 0.2 0.11 11.5 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.1 EEQ72919.1 - 0.076 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Glyco_hydro_17 PF00332.13 EEQ72919.1 - 0.11 11.4 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 3HCDH_N PF02737.13 EEQ72919.1 - 0.16 11.6 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Metallophos PF00149.23 EEQ72920.1 - 9.7e-11 41.4 0.0 2.3e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEQ72920.1 - 4.3e-07 29.8 0.0 6.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EEQ72920.1 - 0.08 12.0 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily MARVEL PF01284.18 EEQ72921.1 - 2.3e-19 69.6 10.9 2.9e-19 69.2 7.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain DoxX_3 PF13781.1 EEQ72921.1 - 0.022 15.1 2.2 0.51 10.7 0.7 2.2 2 0 0 2 2 2 0 DoxX-like family 7TM-7TMR_HD PF07698.6 EEQ72921.1 - 0.039 13.3 3.0 0.059 12.8 1.7 1.5 1 1 0 1 1 1 0 7TM receptor with intracellular HD hydrolase PepSY_TM_2 PF13703.1 EEQ72921.1 - 0.056 13.6 1.4 0.056 13.6 1.0 2.5 3 0 0 3 3 3 0 PepSY-associated TM helix MFS_1 PF07690.11 EEQ72921.1 - 0.19 10.3 10.5 0.4 9.3 4.0 2.0 2 0 0 2 2 2 0 Major Facilitator Superfamily ABC2_membrane_5 PF13346.1 EEQ72921.1 - 0.3 10.3 5.6 0.5 9.6 3.9 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Tic20 PF09685.5 EEQ72921.1 - 0.37 10.8 6.0 0.81 9.7 2.3 2.2 2 0 0 2 2 2 0 Tic20-like protein UPF0233 PF06781.7 EEQ72921.1 - 0.41 10.2 4.6 0.19 11.3 1.2 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) DUF202 PF02656.10 EEQ72921.1 - 1.2 9.3 6.0 49 4.2 4.2 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF202) SCAMP PF04144.8 EEQ72921.1 - 1.9 8.3 8.1 24 4.7 5.6 2.1 1 1 0 1 1 1 0 SCAMP family Pox_A14 PF05767.7 EEQ72921.1 - 3.4 7.6 5.8 0.79 9.7 0.2 2.3 1 1 2 3 3 2 0 Poxvirus virion envelope protein A14 Ftsk_gamma PF09397.5 EEQ72922.1 - 0.043 13.5 0.0 0.094 12.4 0.0 1.6 1 0 0 1 1 1 0 Ftsk gamma domain Nse4_C PF08743.5 EEQ72923.1 - 1.2e-35 121.3 0.0 3e-35 120.0 0.0 1.7 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EEQ72923.1 - 4.9e-17 61.5 0.0 1.5e-16 59.9 0.0 1.9 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF4336 PF14234.1 EEQ72924.1 - 1.7e-21 76.6 0.0 8.6e-17 61.2 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) PI3Ka PF00613.15 EEQ72925.1 - 3.8e-58 195.7 0.3 6.4e-58 194.9 0.2 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EEQ72925.1 - 8.5e-46 156.3 0.0 4.3e-44 150.7 0.0 3.1 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EEQ72925.1 - 4e-30 104.4 0.0 6.8e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.25 EEQ72925.1 - 0.031 14.1 0.0 0.086 12.6 0.0 1.8 1 0 0 1 1 1 0 C2 domain MMR_HSR1 PF01926.18 EEQ72926.1 - 5e-14 52.2 0.1 2.4e-13 50.0 0.0 2.1 1 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEQ72926.1 - 1.3e-05 24.4 0.3 3.7e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EEQ72926.1 - 0.00015 21.0 0.0 0.00025 20.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 IIGP PF05049.8 EEQ72926.1 - 0.0016 17.3 0.0 0.0024 16.7 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.18 EEQ72926.1 - 0.0051 16.6 0.1 0.088 12.6 0.1 2.4 1 1 1 2 2 2 1 Dynamin family ArgK PF03308.11 EEQ72926.1 - 0.007 15.1 0.1 0.011 14.4 0.1 1.3 1 0 0 1 1 1 1 ArgK protein MobB PF03205.9 EEQ72926.1 - 0.0089 15.7 0.1 0.021 14.5 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EEQ72926.1 - 0.02 15.3 0.2 0.049 14.1 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein AIG1 PF04548.11 EEQ72926.1 - 0.083 11.9 0.6 0.13 11.3 0.0 1.6 2 0 0 2 2 2 0 AIG1 family AAA_17 PF13207.1 EEQ72926.1 - 0.13 13.1 0.1 0.31 11.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEQ72926.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EEQ72926.1 - 0.14 11.7 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Isy1 PF06246.7 EEQ72927.1 - 1.2e-83 280.4 0.1 1.7e-83 279.9 0.1 1.2 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.5 EEQ72927.1 - 0.09 12.6 0.1 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 YolD-like protein Myosin_head PF00063.16 EEQ72928.1 - 5.7e-246 817.8 0.0 5.7e-246 817.8 0.0 2.7 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 EEQ72928.1 - 5.8e-27 93.8 268.6 6e-17 60.7 83.0 4.4 2 1 2 4 4 4 4 Myosin tail Filament PF00038.16 EEQ72928.1 - 0.0036 16.8 24.3 0.0036 16.8 16.8 10.0 1 1 6 8 8 8 3 Intermediate filament protein Myosin_N PF02736.14 EEQ72928.1 - 0.013 15.1 0.0 0.037 13.7 0.0 1.8 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 EEQ72928.1 - 0.048 13.4 0.0 0.15 11.7 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain zf-C3H1 PF10650.4 EEQ72929.1 - 5e-12 45.0 3.1 9.5e-12 44.1 2.2 1.5 1 0 0 1 1 1 1 Putative zinc-finger domain Nexin_C PF08628.7 EEQ72929.1 - 0.17 12.0 1.3 0.47 10.5 0.9 1.7 1 0 0 1 1 1 0 Sorting nexin C terminal IncA PF04156.9 EEQ72929.1 - 0.9 9.1 7.5 2.2 7.8 3.1 2.5 2 0 0 2 2 2 0 IncA protein APG6 PF04111.7 EEQ72929.1 - 1.3 7.9 4.8 4.6 6.1 3.3 1.9 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-DHHC PF01529.15 EEQ72934.1 - 4.3e-28 97.8 4.6 4.3e-28 97.8 3.2 2.0 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF2079 PF09852.4 EEQ72934.1 - 0.028 13.1 0.3 0.042 12.5 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) DUF443 PF04276.7 EEQ72934.1 - 2.6 7.4 6.9 4.7 6.5 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF443) DUF4203 PF13886.1 EEQ72934.1 - 3.4 7.0 12.7 4.6 6.6 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) Apelin PF15360.1 EEQ72936.1 - 0.82 9.9 3.9 0.57 10.4 0.4 2.2 2 0 0 2 2 2 0 APJ endogenous ligand Dioxygenase_C PF00775.16 EEQ72945.1 - 1.9e-09 37.0 1.0 4.4e-09 35.8 0.7 1.6 1 1 0 1 1 1 1 Dioxygenase DIM PF08194.7 EEQ72945.1 - 0.069 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 DIM protein Tyrosinase PF00264.15 EEQ72947.1 - 4.4e-32 112.0 1.0 6.6e-32 111.4 0.7 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF2116 PF09889.4 EEQ72947.1 - 0.088 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Glyco_hydro_17 PF00332.13 EEQ72949.1 - 0.00098 18.2 2.0 0.0012 17.9 0.4 1.7 1 1 1 2 2 2 1 Glycosyl hydrolases family 17 SRR1 PF07985.7 EEQ72950.1 - 1.4e-18 66.4 0.0 2.9e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 SRR1 Isochorismatase PF00857.15 EEQ72951.1 - 4.1e-37 127.7 0.1 4.6e-37 127.6 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family OKR_DC_1_N PF03709.10 EEQ72951.1 - 0.004 17.2 0.0 0.0078 16.2 0.0 1.4 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain eIF-5a PF01287.15 EEQ72952.1 - 0.00025 20.9 0.0 0.00052 19.9 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Abhydrolase_6 PF12697.2 EEQ72954.1 - 1.9e-28 99.9 4.5 1e-27 97.5 3.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ72954.1 - 2.2e-12 47.0 1.1 8.3e-12 45.1 0.8 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ72954.1 - 1.3e-10 41.1 0.1 1.1e-09 38.2 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EEQ72954.1 - 4.9e-07 29.4 0.0 2.5e-06 27.2 0.0 2.2 2 1 1 3 3 3 1 Putative lysophospholipase Esterase PF00756.15 EEQ72954.1 - 6.2e-05 22.5 0.0 0.00026 20.4 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 EEQ72954.1 - 0.035 13.3 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family PHD PF00628.24 EEQ72956.1 - 4.2e-09 35.9 2.4 4.2e-09 35.9 1.7 1.7 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EEQ72956.1 - 0.0098 15.1 3.0 0.016 14.4 2.1 1.4 1 0 0 1 1 1 1 PHD-finger TFIIS_C PF01096.13 EEQ72956.1 - 0.51 10.0 0.0 0.51 10.0 0.0 2.7 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) DUF3755 PF12579.3 EEQ72958.1 - 0.17 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3755) MARVEL PF01284.18 EEQ72959.1 - 4e-07 29.9 4.3 6.5e-07 29.2 3.0 1.4 1 1 0 1 1 1 1 Membrane-associating domain DUF1752 PF08550.5 EEQ72960.1 - 1.1e-09 37.7 5.2 1.9e-09 36.9 3.6 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) adh_short_C2 PF13561.1 EEQ72962.1 - 1.7e-27 96.7 0.0 2.2e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEQ72962.1 - 7.3e-19 68.2 0.2 1e-18 67.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ72962.1 - 2.5e-11 43.5 0.1 4e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 KR domain CPSase_L_D2 PF02786.12 EEQ72963.1 - 1.4e-73 246.7 0.0 2.5e-73 245.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EEQ72963.1 - 1.1e-35 121.8 0.0 7.1e-35 119.2 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EEQ72963.1 - 6.7e-34 116.3 0.0 3.1e-33 114.1 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EEQ72963.1 - 1.5e-17 63.8 0.0 4.3e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EEQ72963.1 - 3.3e-14 52.2 1.8 9.4e-14 50.8 0.7 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EEQ72963.1 - 1.9e-13 49.8 0.0 3.4e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EEQ72963.1 - 5.8e-10 38.9 0.0 1.2e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EEQ72963.1 - 0.00048 19.7 0.1 0.044 13.4 0.0 2.6 1 1 1 2 2 2 1 Biotin-lipoyl like RimK PF08443.6 EEQ72963.1 - 0.00097 18.6 0.0 0.0041 16.6 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EEQ72963.1 - 0.001 18.9 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GCV_H PF01597.14 EEQ72963.1 - 0.024 14.2 0.8 0.14 11.8 0.1 2.2 2 0 0 2 2 2 0 Glycine cleavage H-protein Toxin_59 PF15537.1 EEQ72963.1 - 0.034 14.2 0.0 0.27 11.3 0.0 2.5 3 0 0 3 3 3 0 Putative toxin 59 ATPgrasp_ST PF14397.1 EEQ72963.1 - 0.038 13.0 0.0 0.094 11.7 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp PMAIP1 PF15150.1 EEQ72964.1 - 9.7 6.0 6.7 13 5.6 1.2 3.0 2 1 0 2 2 2 0 Phorbol-12-myristate-13-acetate-induced Acyl-CoA_dh_1 PF00441.19 EEQ72965.1 - 4.4e-40 137.2 1.3 7.9e-40 136.3 0.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EEQ72965.1 - 4.8e-26 91.5 0.0 1e-25 90.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EEQ72965.1 - 4.6e-20 70.8 0.4 1.4e-19 69.3 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EEQ72965.1 - 1.7e-16 60.6 0.4 3.2e-16 59.8 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EEQ72965.1 - 0.02 14.2 0.1 0.099 12.0 0.1 1.9 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Carboxyl_trans PF01039.17 EEQ72966.1 - 1.3e-140 469.0 0.0 1.8e-140 468.5 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EEQ72966.1 - 0.048 12.8 0.0 2.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) Ras PF00071.17 EEQ72967.1 - 2.1e-51 173.5 0.0 2.5e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ72967.1 - 6.6e-20 71.7 0.0 1e-19 71.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ72967.1 - 3.4e-11 42.6 0.0 4e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEQ72967.1 - 8.8e-07 28.5 0.0 4.7e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEQ72967.1 - 6.5e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EEQ72967.1 - 0.0031 16.7 0.0 0.0045 16.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EEQ72967.1 - 0.0051 16.9 0.1 0.045 13.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEQ72967.1 - 0.032 14.2 0.0 0.91 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 EEQ72967.1 - 0.055 12.8 0.1 0.23 10.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EEQ72967.1 - 0.11 11.8 0.0 0.34 10.2 0.0 1.9 1 1 0 1 1 1 0 AAA-like domain DUF3014 PF11219.3 EEQ72969.1 - 0.068 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3014) Excalibur PF05901.6 EEQ72970.1 - 0.067 13.5 0.4 0.33 11.3 0.0 2.2 2 0 0 2 2 2 0 Excalibur calcium-binding domain Abhydro_lipase PF04083.11 EEQ72971.1 - 2.1e-24 84.6 0.3 4.8e-24 83.4 0.0 1.7 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EEQ72971.1 - 1e-16 61.2 0.3 1.7e-16 60.4 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 EEQ72971.1 - 6.7e-05 22.4 0.0 0.038 13.4 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EEQ72971.1 - 0.0003 20.5 0.0 0.0014 18.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ72971.1 - 0.00032 20.6 0.0 0.00068 19.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EEQ72971.1 - 0.12 11.6 0.0 1.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Pet191_N PF10203.4 EEQ72972.1 - 3.5e-27 94.2 2.4 4.3e-27 93.9 1.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 PAN_3 PF08277.7 EEQ72972.1 - 0.096 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 PAN-like domain DDOST_48kD PF03345.9 EEQ72973.1 - 1.3e-166 554.3 0.0 1.5e-166 554.1 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta PAN_1 PF00024.21 EEQ72975.1 - 0.02 14.6 1.4 0.028 14.1 1.0 1.2 1 0 0 1 1 1 0 PAN domain DUF1572 PF07609.6 EEQ72976.1 - 0.024 14.2 0.3 0.028 13.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) MAGSP PF03082.9 EEQ72976.1 - 0.17 11.2 1.6 0.19 11.0 1.1 1.1 1 0 0 1 1 1 0 Male accessory gland secretory protein GST_C PF00043.20 EEQ72979.1 - 5.2e-08 32.7 0.0 1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEQ72979.1 - 3.4e-07 30.0 1.9 6.4e-07 29.1 1.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EEQ72979.1 - 0.00051 20.2 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EEQ72979.1 - 0.0024 18.3 0.1 0.0075 16.7 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain IMS PF00817.15 EEQ72980.1 - 2.4e-37 127.9 0.1 9.2e-21 74.1 0.1 2.2 2 0 0 2 2 2 2 impB/mucB/samB family IMS_C PF11799.3 EEQ72980.1 - 8.5e-13 48.3 0.3 1.8e-12 47.3 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain MFS_1 PF07690.11 EEQ72982.1 - 1.6e-15 56.7 27.7 3.2e-15 55.6 19.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily WSC PF01822.14 EEQ72984.1 - 1.6e-09 37.5 7.9 1.6e-09 37.5 5.5 1.9 2 0 0 2 2 2 1 WSC domain Podoplanin PF05808.6 EEQ72984.1 - 0.0003 20.4 0.7 0.00049 19.7 0.5 1.3 1 0 0 1 1 1 1 Podoplanin Glycophorin_A PF01102.13 EEQ72984.1 - 0.001 18.8 3.2 0.002 17.8 1.3 1.9 1 1 1 2 2 2 1 Glycophorin A SKG6 PF08693.5 EEQ72984.1 - 0.022 14.0 0.9 0.061 12.6 0.6 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Herpes_gE PF02480.11 EEQ72984.1 - 0.048 11.9 0.0 0.063 11.5 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF2668 PF10873.3 EEQ72984.1 - 0.099 12.7 0.0 0.099 12.7 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2668) DUF2207 PF09972.4 EEQ72984.1 - 0.17 10.4 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PEGSRP PF07623.6 EEQ72985.1 - 3.6 6.9 6.7 9.8 5.5 4.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) MFS_1 PF07690.11 EEQ72986.1 - 9.4e-22 77.1 31.6 2.7e-21 75.6 19.8 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily PDGLE PF13190.1 EEQ72986.1 - 0.047 13.3 0.1 0.17 11.5 0.1 2.0 1 0 0 1 1 1 0 PDGLE domain Rhabdo_M1 PF03342.8 EEQ72987.1 - 0.046 12.8 0.0 0.068 12.3 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) FAD_binding_3 PF01494.14 EEQ72988.1 - 3.9e-65 220.2 0.0 7.8e-64 215.9 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EEQ72988.1 - 2.5e-22 79.2 0.0 4.7e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.5 EEQ72988.1 - 0.00076 18.3 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase PRP38 PF03371.10 EEQ72990.1 - 2.3e-67 225.9 0.0 2.8e-67 225.6 0.0 1.0 1 0 0 1 1 1 1 PRP38 family WD40 PF00400.27 EEQ72992.1 - 8.7e-20 69.8 6.6 0.0098 15.7 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat AAA_12 PF13087.1 EEQ72994.1 - 2.8e-35 121.5 0.0 4.5e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEQ72994.1 - 7.8e-26 91.0 0.2 1.1e-24 87.3 0.3 2.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEQ72994.1 - 9.3e-09 34.9 0.1 2.9e-08 33.3 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EEQ72994.1 - 1.1e-08 34.8 0.0 2.8e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EEQ72994.1 - 6.7e-05 22.5 0.0 0.084 12.3 0.0 3.5 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EEQ72994.1 - 0.0054 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EEQ72994.1 - 0.0056 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.11 EEQ72994.1 - 0.0083 15.3 0.0 0.028 13.6 0.0 1.8 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.4 EEQ72994.1 - 0.0084 15.1 0.0 0.26 10.2 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) SLT_beta PF02258.11 EEQ72994.1 - 0.11 12.3 0.1 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Shiga-like toxin beta subunit ABC_tran PF00005.22 EEQ72995.1 - 3.5e-54 182.8 0.2 3.5e-31 108.3 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 EEQ72995.1 - 1.1e-47 162.7 17.3 2.2e-28 99.4 4.4 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 EEQ72995.1 - 1.4e-07 31.8 3.4 0.002 18.1 0.3 3.8 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEQ72995.1 - 2.3e-07 30.4 0.0 0.026 13.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EEQ72995.1 - 2.7e-07 30.0 4.4 0.028 13.6 0.7 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EEQ72995.1 - 0.00012 21.5 0.2 0.57 9.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EEQ72995.1 - 0.00021 21.3 0.1 0.39 10.6 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 EEQ72995.1 - 0.00039 20.8 11.2 0.0015 18.9 0.0 3.5 3 1 0 3 3 2 2 AAA domain T2SE PF00437.15 EEQ72995.1 - 0.00039 19.4 0.0 0.035 12.9 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Zeta_toxin PF06414.7 EEQ72995.1 - 0.00076 18.6 0.6 0.28 10.2 0.1 2.5 2 0 0 2 2 2 2 Zeta toxin DUF258 PF03193.11 EEQ72995.1 - 0.001 18.2 0.2 1 8.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 EEQ72995.1 - 0.0017 17.8 0.5 0.63 9.4 0.0 2.8 3 0 0 3 3 3 1 AAA-like domain MMR_HSR1 PF01926.18 EEQ72995.1 - 0.0027 17.6 0.2 0.19 11.6 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EEQ72995.1 - 0.0043 17.5 0.4 4.4 7.8 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_17 PF13207.1 EEQ72995.1 - 0.0047 17.7 0.1 4.5 8.1 0.0 3.2 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EEQ72995.1 - 0.0053 16.2 0.0 0.91 8.9 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF1700 PF08006.6 EEQ72995.1 - 0.0054 16.0 1.0 0.017 14.4 0.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1700) AAA_18 PF13238.1 EEQ72995.1 - 0.006 16.8 0.1 6.5 7.0 0.1 3.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EEQ72995.1 - 0.025 14.7 1.6 20 5.3 0.0 3.5 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 EEQ72995.1 - 0.031 14.1 0.0 0.031 14.1 0.0 3.0 4 0 0 4 4 3 0 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 EEQ72995.1 - 0.031 13.7 0.1 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 EEQ72995.1 - 0.034 13.5 0.2 7.1 5.9 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein MobB PF03205.9 EEQ72995.1 - 0.07 12.8 0.1 8.4 6.1 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.10 EEQ72995.1 - 0.2 11.4 0.9 6.7 6.4 0.0 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA PF00004.24 EEQ72995.1 - 0.57 10.3 3.0 19 5.4 0.2 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) UQ_con PF00179.21 EEQ72996.1 - 3.6e-38 130.1 0.0 4.5e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EEQ72996.1 - 0.054 13.3 0.2 0.11 12.3 0.2 1.6 1 1 0 1 1 1 0 RWD domain Glyco_transf_90 PF05686.7 EEQ72997.1 - 1.1e-14 53.9 1.1 1.6e-10 40.2 0.0 2.7 3 0 0 3 3 3 2 Glycosyl transferase family 90 Bax1-I PF01027.15 EEQ72998.1 - 6.3e-46 156.5 28.9 7.4e-46 156.3 20.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Orbi_NS3 PF01616.11 EEQ72998.1 - 0.029 13.3 1.7 0.19 10.6 0.3 2.2 2 0 0 2 2 2 0 Orbivirus NS3 7TMR-DISM_7TM PF07695.6 EEQ72998.1 - 0.091 12.4 29.8 1.2 8.7 11.0 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling MerC PF03203.9 EEQ72998.1 - 0.57 10.5 10.0 0.27 11.5 0.8 2.3 1 1 1 2 2 2 0 MerC mercury resistance protein DUF2636 PF11120.3 EEQ72998.1 - 1.9 8.0 5.0 1.9 8.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2636) Aa_trans PF01490.13 EEQ72999.1 - 8.3e-83 278.1 20.1 1.4e-82 277.3 13.9 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3417 PF11897.3 EEQ72999.1 - 0.18 11.7 1.2 0.72 9.8 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3417) DUF1479 PF07350.7 EEQ73000.1 - 9.6e-164 544.7 0.0 1.1e-163 544.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) DUF1620 PF07774.8 EEQ73001.1 - 1.1e-77 260.2 0.0 2e-77 259.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EEQ73001.1 - 1.2e-20 74.0 14.5 3.9e-17 62.5 1.0 3.8 3 1 1 4 4 4 2 PQQ-like domain PQQ PF01011.16 EEQ73001.1 - 5e-07 28.9 6.2 1.1 8.9 0.3 6.9 8 0 0 8 8 8 3 PQQ enzyme repeat SKG6 PF08693.5 EEQ73002.1 - 6.5e-05 22.1 1.5 0.00015 21.0 1.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 EEQ73002.1 - 0.00055 18.3 0.0 0.0012 17.1 0.0 1.5 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 EEQ73002.1 - 0.0023 16.8 0.0 0.0035 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Protocadherin PF08374.6 EEQ73002.1 - 0.0023 17.6 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 Protocadherin EphA2_TM PF14575.1 EEQ73002.1 - 0.0026 18.0 0.2 0.0091 16.3 0.1 1.9 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.1 EEQ73002.1 - 0.017 14.7 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 TMEM154 PF15102.1 EEQ73002.1 - 0.048 13.3 0.1 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family Syndecan PF01034.15 EEQ73002.1 - 0.1 12.2 0.5 0.18 11.4 0.3 1.3 1 0 0 1 1 1 0 Syndecan domain Rifin_STEVOR PF02009.11 EEQ73002.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Rifin/stevor family AT_hook PF02178.14 EEQ73003.1 - 5.8e-07 28.4 39.7 0.078 12.6 3.2 5.0 4 0 0 4 4 4 4 AT hook motif CRAL_TRIO PF00650.15 EEQ73004.1 - 1.7e-25 89.3 0.0 3.3e-25 88.4 0.0 1.4 2 0 0 2 2 2 1 CRAL/TRIO domain SNase PF00565.12 EEQ73005.1 - 7.9e-76 251.2 0.1 1.8e-25 89.3 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EEQ73005.1 - 1e-27 96.3 0.0 3.2e-27 94.7 0.0 1.9 2 0 0 2 2 2 1 Tudor domain SMN PF06003.7 EEQ73005.1 - 0.016 14.3 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF3297 PF11730.3 EEQ73005.1 - 0.056 13.1 0.0 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3297) DUF2855 PF11017.3 EEQ73006.1 - 1e-57 195.6 0.0 1.2e-57 195.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) Fungal_trans PF04082.13 EEQ73007.1 - 1.6e-16 59.9 0.0 1.6e-16 59.9 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ73007.1 - 4.3e-06 26.5 9.7 8.7e-06 25.5 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sod_Cu PF00080.15 EEQ73008.1 - 3.1e-47 160.3 3.1 3.6e-47 160.0 2.1 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF4246 PF14033.1 EEQ73009.1 - 1.2e-181 604.7 0.0 1.9e-181 604.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Transaldolase PF00923.14 EEQ73010.1 - 3.8e-95 318.3 0.2 4.3e-95 318.1 0.2 1.0 1 0 0 1 1 1 1 Transaldolase Beach PF02138.13 EEQ73011.1 - 3.6e-108 361.1 0.1 7.7e-108 360.0 0.1 1.6 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EEQ73011.1 - 7.7e-12 44.9 0.0 2.1e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EEQ73011.1 - 5.6e-09 35.5 3.8 2.9e-05 23.7 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Laminin_G_3 PF13385.1 EEQ73011.1 - 8e-08 32.6 0.0 1.9e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Peptidase_S8 PF00082.17 EEQ73012.1 - 1.3e-52 178.7 7.6 1.9e-52 178.1 5.2 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EEQ73012.1 - 4.1e-20 72.1 0.4 9e-20 71.0 0.3 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF188 PF02639.9 EEQ73013.1 - 0.042 13.2 0.0 2 7.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized BCR, YaiI/YqxD family COG1671 Abhydrolase_2 PF02230.11 EEQ73014.1 - 9.6e-14 51.3 0.0 1.2e-11 44.5 0.0 2.0 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EEQ73014.1 - 5.9e-06 26.3 0.5 7.6e-06 25.9 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ73014.1 - 0.0014 18.3 0.1 0.0021 17.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Metallophos PF00149.23 EEQ73016.1 - 2.7e-41 141.1 0.3 4.1e-41 140.5 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1647 PF07801.6 EEQ73016.1 - 0.14 11.6 1.2 1.6 8.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) HisKA PF00512.20 EEQ73016.1 - 0.27 11.2 1.8 2.9 7.9 0.2 2.7 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain CWC25 PF12542.3 EEQ73017.1 - 0.048 14.1 0.7 0.19 12.1 0.0 1.9 2 0 0 2 2 2 0 Pre-mRNA splicing factor An_peroxidase PF03098.10 EEQ73018.1 - 1.2e-82 278.0 0.0 1.8e-80 270.8 0.0 2.3 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EEQ73018.1 - 1.3e-11 43.7 0.0 2.2e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 GerE PF00196.14 EEQ73018.1 - 0.052 12.8 0.1 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_38 PF13936.1 EEQ73018.1 - 0.099 12.2 0.0 0.71 9.4 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2235 PF09994.4 EEQ73019.1 - 2.7e-90 302.5 0.2 3.4e-90 302.1 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Peroxidase_2 PF01328.12 EEQ73020.1 - 2e-57 194.2 0.0 2.8e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Voldacs PF03517.8 EEQ73021.1 - 4.6e-36 123.6 2.5 7.8e-36 122.9 1.7 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Pap_E4 PF02711.9 EEQ73021.1 - 0.25 12.1 10.3 1.1 10.0 4.2 2.7 2 0 0 2 2 2 0 E4 protein PAT1 PF09770.4 EEQ73021.1 - 0.99 7.5 12.8 1.1 7.3 8.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NAD_binding_3 PF03447.11 EEQ73023.1 - 0.0013 19.1 0.3 0.014 15.7 0.1 1.9 1 1 1 2 2 2 1 Homoserine dehydrogenase, NAD binding domain DUF2704 PF10866.3 EEQ73023.1 - 0.0071 15.7 1.6 0.0071 15.7 1.1 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2704) DUF2012 PF09430.5 EEQ73023.1 - 0.089 12.6 0.1 0.15 11.9 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2012) DUF3399 PF11879.3 EEQ73023.1 - 0.19 11.9 1.3 0.21 11.8 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) DUF4058 PF13267.1 EEQ73023.1 - 0.24 10.4 3.6 0.77 8.8 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4058) adh_short PF00106.20 EEQ73024.1 - 1.5e-24 86.8 2.8 2.3e-24 86.1 2.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ73024.1 - 1.6e-24 86.9 0.4 2.1e-24 86.6 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ73024.1 - 3.5e-10 39.8 1.7 6.2e-10 39.0 1.2 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EEQ73024.1 - 5.3e-05 22.7 0.8 0.021 14.2 0.1 2.3 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 EEQ73024.1 - 0.0012 17.9 0.4 0.0051 15.9 0.0 2.1 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EEQ73024.1 - 0.0026 17.5 1.5 0.057 13.1 0.5 2.3 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EEQ73024.1 - 0.02 14.3 0.1 0.04 13.3 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Eno-Rase_NADH_b PF12242.3 EEQ73024.1 - 0.035 13.8 1.5 0.091 12.5 1.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 EEQ73024.1 - 0.041 13.5 0.5 0.067 12.8 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.10 EEQ73024.1 - 0.074 12.6 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus HMG_CoA_synt_C PF08540.5 EEQ73024.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal TIM-br_sig_trns PF09370.5 EEQ73024.1 - 0.17 10.9 0.9 0.32 9.9 0.2 1.7 2 0 0 2 2 2 0 TIM-barrel signal transduction protein APH PF01636.18 EEQ73025.1 - 2.9e-18 66.4 0.0 3.7e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ73025.1 - 0.0014 18.2 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EEQ73025.1 - 0.0071 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 EEQ73025.1 - 0.088 12.1 0.0 0.35 10.1 0.0 1.8 2 0 0 2 2 2 0 RIO1 family DUF1092 PF06485.6 EEQ73026.1 - 0.016 14.1 0.3 0.018 13.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1092) Ino80_Iec3 PF14612.1 EEQ73026.1 - 0.03 14.3 2.8 0.033 14.2 1.9 1.2 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling Penicillinase_R PF03965.11 EEQ73026.1 - 0.065 13.3 0.9 0.077 13.0 0.6 1.4 1 0 0 1 1 1 0 Penicillinase repressor PIN_2 PF10130.4 EEQ73026.1 - 0.24 11.4 2.6 0.28 11.2 1.3 1.5 1 1 0 1 1 1 0 PIN domain DUF1049 PF06305.6 EEQ73026.1 - 8.1 6.0 6.0 4.1 6.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) SGS PF05002.10 EEQ73029.1 - 2.7e-24 84.7 14.5 3.1e-24 84.5 7.8 2.6 2 1 0 2 2 2 1 SGS domain CS PF04969.11 EEQ73029.1 - 1.1e-15 57.8 0.1 2.2e-15 56.9 0.1 1.5 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 EEQ73029.1 - 1.9e-06 27.4 1.1 3.6e-05 23.3 0.6 2.2 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EEQ73029.1 - 0.00011 21.8 0.4 0.46 10.5 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ73029.1 - 0.00055 19.4 0.1 0.075 12.6 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ73029.1 - 0.0038 17.8 5.8 0.77 10.5 4.3 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ73029.1 - 0.026 14.8 0.3 13 6.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat CcmH PF03918.9 EEQ73029.1 - 0.061 12.3 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Prenyltrans PF00432.16 EEQ73030.1 - 3.3e-34 116.1 1.7 1.4e-11 43.7 0.1 5.3 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EEQ73030.1 - 7.1e-34 116.6 6.5 5.8e-14 52.4 0.1 4.8 3 2 2 5 5 5 5 Prenyltransferase-like Prenyltrans_1 PF13243.1 EEQ73030.1 - 1.3e-27 95.9 0.1 8.6e-18 64.3 0.1 5.2 5 1 1 6 6 6 4 Prenyltransferase-like Pec_lyase PF09492.5 EEQ73030.1 - 5.2e-07 29.1 2.2 0.52 9.4 0.0 5.1 4 1 2 6 6 6 2 Pectic acid lyase A2M_comp PF07678.9 EEQ73030.1 - 0.0016 17.7 0.1 0.085 12.0 0.0 2.9 2 1 0 2 2 2 1 A-macroglobulin complement component Mago-bind PF09282.5 EEQ73030.1 - 0.089 12.3 0.2 0.19 11.3 0.2 1.5 1 0 0 1 1 1 0 Mago binding Choline_transpo PF04515.7 EEQ73032.1 - 0.058 12.1 0.3 0.072 11.8 0.2 1.1 1 0 0 1 1 1 0 Plasma-membrane choline transporter Opi1 PF08618.5 EEQ73033.1 - 2.3e-93 313.4 0.2 7e-55 186.6 5.8 3.4 1 1 2 3 3 3 3 Transcription factor Opi1 RdRP PF05183.7 EEQ73034.1 - 1.7e-122 410.0 0.0 2.7e-122 409.4 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase eIF3_p135 PF12807.2 EEQ73035.1 - 0.016 15.1 0.2 0.016 15.1 0.1 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 YscO PF07321.7 EEQ73035.1 - 0.037 13.8 0.0 0.038 13.8 0.0 1.1 1 0 0 1 1 1 0 Type III secretion protein YscO IFN-gamma PF00714.12 EEQ73035.1 - 0.13 12.1 1.8 0.23 11.3 1.2 1.5 1 1 0 1 1 1 0 Interferon gamma tRNA-synt_1e PF01406.14 EEQ73036.1 - 2.6e-111 371.5 0.1 9.2e-110 366.4 0.1 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EEQ73036.1 - 0.00012 20.8 0.8 0.11 11.1 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.6 EEQ73036.1 - 0.019 15.2 0.0 0.085 13.1 0.0 2.2 1 0 0 1 1 1 0 DALR domain GCD14 PF08704.5 EEQ73037.1 - 1.3e-59 201.7 0.0 1.4e-58 198.3 0.0 2.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 EEQ73037.1 - 0.0093 15.9 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ73037.1 - 0.09 13.3 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TPR_11 PF13414.1 EEQ73038.1 - 1.2e-09 37.6 0.0 1.9e-08 33.8 0.0 2.6 2 0 0 2 2 2 1 TPR repeat UBA PF00627.26 EEQ73038.1 - 9.3e-06 25.3 0.0 4.2e-05 23.2 0.0 2.2 1 0 0 1 1 1 1 UBA/TS-N domain TPR_2 PF07719.12 EEQ73038.1 - 0.0003 20.4 0.1 1 9.4 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ73038.1 - 0.0004 20.2 0.1 0.22 11.4 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat DnaJ PF00226.26 EEQ73038.1 - 0.0088 15.7 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.23 EEQ73038.1 - 0.018 14.6 0.0 2.8 7.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat AA_permease PF00324.16 EEQ73039.1 - 1.8e-121 405.8 34.3 2.2e-121 405.5 23.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ73039.1 - 1e-34 119.8 35.4 1.3e-34 119.5 24.5 1.1 1 0 0 1 1 1 1 Amino acid permease MRP-L47 PF06984.8 EEQ73040.1 - 0.02 14.8 0.3 3.3 7.6 0.2 2.2 2 0 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Gtr1_RagA PF04670.7 EEQ73041.1 - 1.3e-90 302.5 0.2 1.7e-90 302.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EEQ73041.1 - 4.2e-08 32.7 0.0 6.5e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EEQ73041.1 - 5.3e-08 32.2 0.0 8e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EEQ73041.1 - 2.2e-06 28.1 0.0 5.2e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEQ73041.1 - 5.4e-06 26.3 0.0 1.4e-05 25.0 0.0 1.6 1 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EEQ73041.1 - 0.0015 17.9 0.3 0.0058 16.1 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EEQ73041.1 - 0.0019 17.6 0.1 0.0034 16.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF815 PF05673.8 EEQ73041.1 - 0.012 14.5 0.1 0.02 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 EEQ73041.1 - 0.015 15.6 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 EEQ73041.1 - 0.063 12.4 0.0 0.16 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AIG1 PF04548.11 EEQ73041.1 - 0.14 11.2 1.0 0.49 9.4 0.2 2.2 2 1 0 2 2 2 0 AIG1 family AAA_10 PF12846.2 EEQ73041.1 - 0.15 11.5 0.3 0.26 10.6 0.2 1.8 1 1 0 1 1 1 0 AAA-like domain G-alpha PF00503.15 EEQ73041.1 - 0.23 10.1 3.1 3.2 6.3 0.8 2.2 1 1 1 2 2 2 0 G-protein alpha subunit DUF1688 PF07958.6 EEQ73042.1 - 7.2e-179 594.6 0.0 8.3e-179 594.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) TP6A_N PF04406.9 EEQ73043.1 - 3.4e-19 68.2 0.0 6e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase UQ_con PF00179.21 EEQ73044.1 - 3e-50 169.2 0.0 3.4e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Scramblase PF03803.10 EEQ73045.1 - 5.5e-54 182.5 0.0 1.4e-29 102.7 0.0 3.0 1 1 1 2 2 2 2 Scramblase DUF533 PF04391.7 EEQ73045.1 - 1.3 8.4 10.2 3 7.1 7.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Sporozoite_P67 PF05642.6 EEQ73045.1 - 6.2 4.5 12.2 0.77 7.5 4.2 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen PepSY_TM_3 PF13706.1 EEQ73046.1 - 0.34 10.3 2.3 0.56 9.6 1.6 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix Ribosomal_L27 PF01016.14 EEQ73047.1 - 4.7e-27 93.5 0.2 4.7e-27 93.5 0.1 1.9 2 0 0 2 2 2 1 Ribosomal L27 protein DUF3653 PF12375.3 EEQ73047.1 - 0.44 10.7 3.9 18 5.6 0.4 2.8 2 1 0 2 2 2 0 Phage protein Rad9_Rad53_bind PF08605.5 EEQ73048.1 - 4.7e-13 49.0 0.0 7.8e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 EEQ73048.1 - 1e-06 28.7 0.0 2.5e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain tRNA_int_endo PF01974.12 EEQ73049.1 - 5.1e-20 71.0 0.1 1.3e-19 69.7 0.1 1.7 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EEQ73049.1 - 8.2e-08 31.6 0.0 0.00013 21.4 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Nop10p PF04135.7 EEQ73050.1 - 1.6e-21 75.7 0.1 1.9e-21 75.5 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family NOB1_Zn_bind PF08772.6 EEQ73051.1 - 1.6e-31 107.9 1.5 2.6e-31 107.2 1.1 1.3 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 EEQ73051.1 - 6.1e-06 26.0 4.3 6.1e-06 26.0 3.0 2.5 2 0 0 2 2 2 1 Drug resistance and apoptosis regulator zf-NADH-PPase PF09297.6 EEQ73051.1 - 0.0077 15.7 0.5 0.025 14.0 0.3 1.9 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Nop14 PF04147.7 EEQ73051.1 - 0.62 7.9 7.4 0.88 7.4 5.2 1.2 1 0 0 1 1 1 0 Nop14-like family Peptidase_M18 PF02127.10 EEQ73052.1 - 1.9e-131 438.5 0.0 2.2e-131 438.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Glyco_hydro_71 PF03659.9 EEQ73053.1 - 4.5e-140 466.5 0.9 6.1e-140 466.0 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 ABC2_membrane PF01061.19 EEQ73054.1 - 9.9e-62 207.8 46.3 2.3e-35 121.6 5.5 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EEQ73054.1 - 4.1e-26 91.8 0.0 1.9e-16 60.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EEQ73054.1 - 5.9e-25 86.9 5.8 3.6e-23 81.1 0.0 3.0 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 EEQ73054.1 - 7.8e-11 41.5 33.6 3e-06 26.5 14.5 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.1 EEQ73054.1 - 0.00049 19.9 0.0 0.0014 18.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EEQ73054.1 - 0.002 17.6 0.1 0.0057 16.1 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EEQ73054.1 - 0.0032 17.4 3.7 0.071 13.0 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EEQ73054.1 - 0.0032 17.4 0.0 0.0075 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EEQ73054.1 - 0.0042 16.5 0.3 0.012 15.0 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EEQ73054.1 - 0.0044 17.8 0.0 0.016 16.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 EEQ73054.1 - 0.0076 15.7 0.9 0.013 14.9 0.6 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EEQ73054.1 - 0.011 14.8 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 EEQ73054.1 - 0.013 15.4 0.4 0.031 14.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EEQ73054.1 - 0.036 14.3 0.5 0.13 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EEQ73054.1 - 0.036 14.1 0.0 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EEQ73054.1 - 0.077 12.6 0.2 2.7 7.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 EEQ73054.1 - 0.11 12.7 1.4 0.35 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Adap_comp_sub PF00928.16 EEQ73059.1 - 3.7e-90 301.5 0.0 5e-90 301.1 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EEQ73059.1 - 2.2e-09 37.1 0.2 3.6e-09 36.4 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 EEQ73059.1 - 0.088 11.9 0.0 0.22 10.6 0.0 1.6 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Ribonucleas_3_3 PF14622.1 EEQ73060.1 - 2.8e-24 85.4 0.0 5.5e-24 84.5 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EEQ73060.1 - 0.0069 16.8 0.0 0.019 15.4 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease III domain Sdh_cyt PF01127.17 EEQ73061.1 - 5e-24 84.4 3.6 6.5e-24 84.0 2.5 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit NMO PF03060.10 EEQ73062.1 - 3.9e-64 216.8 0.3 5.6e-64 216.3 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EEQ73062.1 - 3.9e-11 42.4 0.0 0.00018 20.5 0.1 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EEQ73062.1 - 0.0011 17.8 0.2 0.0023 16.8 0.2 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.9 EEQ73062.1 - 0.081 11.8 0.1 0.19 10.7 0.0 1.6 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.12 EEQ73062.1 - 0.088 11.7 0.7 0.21 10.4 0.5 1.7 1 1 0 1 1 1 0 Conserved region in glutamate synthase Hydrophobin PF01185.13 EEQ73063.1 - 9.4e-15 54.8 10.4 1.2e-14 54.4 7.2 1.2 1 0 0 1 1 1 1 Fungal hydrophobin DUF1251 PF06856.6 EEQ73063.1 - 0.059 12.8 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1251) FAD_binding_2 PF00890.19 EEQ73065.1 - 6.8e-89 298.5 10.3 3.6e-77 259.9 0.4 2.2 1 1 1 2 2 2 2 FAD binding domain Succ_DH_flav_C PF02910.15 EEQ73065.1 - 8.3e-43 145.3 0.6 1.2e-42 144.7 0.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EEQ73065.1 - 0.00013 21.8 2.1 0.0011 18.8 1.1 2.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEQ73065.1 - 0.001 18.0 0.5 0.069 11.9 0.6 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EEQ73065.1 - 0.0016 17.5 2.1 0.0027 16.8 1.5 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EEQ73065.1 - 0.09 11.8 3.0 0.41 9.7 0.7 2.4 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 EEQ73065.1 - 0.14 10.5 5.1 0.13 10.6 2.3 1.8 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.19 EEQ73065.1 - 0.52 9.1 5.3 1.2 8.0 2.5 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase PfkB PF00294.19 EEQ73065.1 - 7.7 5.5 6.9 1.1 8.3 1.4 2.0 3 0 0 3 3 3 0 pfkB family carbohydrate kinase WW PF00397.21 EEQ73066.1 - 2e-07 30.7 1.9 6.6e-07 29.0 1.3 1.9 1 0 0 1 1 1 1 WW domain Ank_2 PF12796.2 EEQ73067.1 - 1.5e-14 54.0 0.1 3.7e-14 52.8 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEQ73067.1 - 1.1e-11 44.5 4.9 6.1e-10 39.0 1.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEQ73067.1 - 1.4e-11 44.5 1.2 4.5e-06 27.0 0.1 3.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.25 EEQ73067.1 - 1.7e-11 43.2 2.3 8e-10 38.0 0.2 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 EEQ73067.1 - 2.5e-10 39.5 0.6 2.8e-06 27.0 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Glyco_tranf_2_3 PF13641.1 EEQ73068.1 - 3.2e-11 43.4 0.0 2.4e-10 40.5 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EEQ73068.1 - 1.4e-10 40.7 0.3 3.1e-05 23.3 0.0 3.7 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EEQ73068.1 - 0.004 16.8 0.0 0.019 14.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 E1-E2_ATPase PF00122.15 EEQ73071.1 - 3.7e-44 150.4 0.7 4.3e-34 117.5 0.0 2.4 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEQ73071.1 - 3.1e-25 88.7 3.9 2.6e-16 59.6 0.0 3.4 2 1 1 3 3 3 3 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEQ73071.1 - 1.1e-21 78.2 0.0 3.3e-21 76.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEQ73071.1 - 8.4e-14 50.7 0.0 3.4e-13 48.8 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EEQ73071.1 - 4.4e-10 40.0 0.0 8.8e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEQ73071.1 - 6.7e-06 25.8 0.3 2.7e-05 23.8 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ73071.1 - 0.011 15.6 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF1469 PF07332.6 EEQ73071.1 - 0.42 10.3 4.3 2.1 8.0 3.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Pyr_redox_3 PF13738.1 EEQ73072.1 - 5.9e-19 68.9 0.0 1.6e-18 67.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EEQ73072.1 - 3.7e-14 51.8 0.0 1.1e-12 47.0 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EEQ73072.1 - 7.5e-10 38.2 0.0 1.9e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EEQ73072.1 - 3.7e-05 23.7 0.0 8.2e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEQ73072.1 - 0.00052 19.1 0.1 0.035 13.2 0.0 2.8 3 0 0 3 3 3 1 Thi4 family NAD_binding_8 PF13450.1 EEQ73072.1 - 0.0011 18.9 0.5 0.0048 16.9 0.0 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EEQ73072.1 - 0.0086 15.8 0.0 0.47 10.2 0.0 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EEQ73072.1 - 0.098 11.5 0.1 5.9 5.6 0.0 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase HpaB PF03241.8 EEQ73073.1 - 0.027 13.3 0.0 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal KAT11 PF08214.6 EEQ73074.1 - 9.6e-102 340.6 0.0 1.3e-101 340.1 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein Cupin_2 PF07883.6 EEQ73075.1 - 1.7e-06 27.3 0.0 2.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Hid1 PF12722.2 EEQ73077.1 - 8.1e-279 927.1 0.0 1.2e-278 926.5 0.0 1.3 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EEQ73077.1 - 2.2e-79 267.3 0.0 3.4e-79 266.7 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein NPCC PF08058.6 EEQ73078.1 - 6.9e-33 113.5 0.0 7.4e-32 110.1 0.0 2.0 1 1 0 1 1 1 1 Nuclear pore complex component AMP-binding PF00501.23 EEQ73079.1 - 2.4e-07 29.5 0.0 0.00046 18.6 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Ribosomal_L19 PF01245.15 EEQ73081.1 - 4.1e-18 65.2 0.0 9.4e-18 64.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L19 ADH_N PF08240.7 EEQ73082.1 - 9e-29 99.4 0.3 1.8e-28 98.4 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 EEQ73082.1 - 5.3e-06 25.9 0.6 1.2e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 EEQ73082.1 - 0.00055 19.4 0.1 0.19 11.2 0.0 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase FANCL_C PF11793.3 EEQ73082.1 - 0.041 13.8 0.3 0.078 12.9 0.2 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Methyltransf_24 PF13578.1 EEQ73083.1 - 4.2e-13 50.0 0.0 1.1e-12 48.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.12 EEQ73083.1 - 7.1e-07 28.4 0.0 3.1e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EEQ73083.1 - 0.00028 21.4 0.0 0.001 19.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ73083.1 - 0.037 13.6 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CmcI PF04989.7 EEQ73083.1 - 0.041 13.1 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase DUF2089 PF09862.4 EEQ73083.1 - 0.066 12.9 0.0 0.47 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) Hap4_Hap_bind PF10297.4 EEQ73084.1 - 2.1e-09 36.8 7.1 4.8e-09 35.7 4.9 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 EEQ73084.1 - 1.1e-08 34.8 9.5 2.1e-06 27.5 5.7 2.6 1 1 1 2 2 2 2 bZIP transcription factor EzrA PF06160.7 EEQ73084.1 - 0.0031 15.7 0.7 0.0055 14.9 0.5 1.3 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA bZIP_2 PF07716.10 EEQ73084.1 - 0.005 16.6 4.6 0.005 16.6 3.2 2.4 2 1 0 2 2 2 1 Basic region leucine zipper Spc7 PF08317.6 EEQ73084.1 - 0.052 12.1 3.5 0.077 11.6 2.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein MAD PF05557.8 EEQ73084.1 - 0.07 11.2 8.0 0.12 10.4 5.6 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Filament PF00038.16 EEQ73084.1 - 0.19 11.1 7.0 0.3 10.5 4.9 1.2 1 0 0 1 1 1 0 Intermediate filament protein DivIVA PF05103.8 EEQ73084.1 - 0.42 10.6 4.6 0.15 12.1 0.7 2.0 1 1 0 1 1 1 0 DivIVA protein Phage_GP20 PF06810.6 EEQ73084.1 - 0.66 9.3 3.4 1.1 8.6 2.4 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 CR6_interact PF10147.4 EEQ73084.1 - 1.6 8.0 10.8 3.6 6.8 7.5 1.6 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 ADIP PF11559.3 EEQ73084.1 - 2.3 8.0 10.0 0.057 13.3 2.3 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Mito_carr PF00153.22 EEQ73085.1 - 6.7e-09 35.3 0.0 1.9 8.2 0.0 5.5 5 1 0 5 5 5 5 Mitochondrial carrier protein Fer2 PF00111.22 EEQ73086.1 - 6.9e-14 51.3 0.5 1e-13 50.8 0.4 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Rrp15p PF07890.7 EEQ73087.1 - 1.1e-36 125.6 6.0 1.1e-36 125.6 4.2 2.3 2 0 0 2 2 2 1 Rrp15p CytochromB561_N PF09786.4 EEQ73087.1 - 0.19 10.1 11.7 0.25 9.7 8.1 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal SRP54 PF00448.17 EEQ73088.1 - 4.7e-74 248.0 2.4 7.4e-74 247.4 1.7 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EEQ73088.1 - 1.1e-24 86.7 0.2 1.1e-24 86.7 0.1 4.3 3 1 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.14 EEQ73088.1 - 2.2e-14 53.3 0.1 4.5e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EEQ73088.1 - 2e-09 37.1 0.2 5.9e-09 35.6 0.1 1.8 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EEQ73088.1 - 9.6e-07 28.7 0.2 2.4e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EEQ73088.1 - 1.8e-05 24.4 0.1 5.6e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EEQ73088.1 - 4e-05 24.4 0.0 0.00012 22.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEQ73088.1 - 0.00011 22.2 0.1 0.00035 20.5 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain CbiA PF01656.18 EEQ73088.1 - 0.00015 21.2 0.3 0.00055 19.4 0.2 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EEQ73088.1 - 0.00017 21.5 0.0 0.83 9.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EEQ73088.1 - 0.00017 20.4 1.3 0.00063 18.6 0.1 2.5 2 1 0 2 2 2 1 ArgK protein APS_kinase PF01583.15 EEQ73088.1 - 0.00082 19.0 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.7 EEQ73088.1 - 0.0014 17.7 0.1 0.0014 17.7 0.0 2.0 2 0 0 2 2 1 1 Zeta toxin AAA_22 PF13401.1 EEQ73088.1 - 0.0021 18.1 0.0 0.0082 16.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain ATP_bind_1 PF03029.12 EEQ73088.1 - 0.0042 16.6 0.3 0.019 14.4 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Thymidylate_kin PF02223.12 EEQ73088.1 - 0.0082 15.5 0.1 0.029 13.7 0.0 2.0 2 0 0 2 2 1 1 Thymidylate kinase AAA_18 PF13238.1 EEQ73088.1 - 0.012 15.8 0.1 0.032 14.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.13 EEQ73088.1 - 0.014 14.4 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase TrwB_AAD_bind PF10412.4 EEQ73088.1 - 0.02 13.5 0.0 0.052 12.1 0.0 1.6 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_28 PF13521.1 EEQ73088.1 - 0.021 14.7 0.1 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EEQ73088.1 - 0.042 13.2 0.2 0.18 11.2 0.1 2.1 2 1 0 2 2 2 0 AAA domain SRPRB PF09439.5 EEQ73088.1 - 0.054 12.7 1.0 2.2 7.4 0.0 2.8 2 1 0 3 3 3 0 Signal recognition particle receptor beta subunit VirE PF05272.6 EEQ73088.1 - 0.06 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E AAA_10 PF12846.2 EEQ73088.1 - 0.072 12.5 0.0 0.15 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA-like domain PhoD PF09423.5 EEQ73089.1 - 1.4e-60 205.1 0.0 2e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase Glyco_hydro_18 PF00704.23 EEQ73090.1 - 4.1e-11 42.9 0.0 1.4e-10 41.1 0.0 1.6 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 Bax1-I PF01027.15 EEQ73091.1 - 0.007 15.9 1.7 0.013 15.1 1.2 1.5 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4131 PF13567.1 EEQ73091.1 - 4 6.8 6.2 50 3.2 4.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) adh_short_C2 PF13561.1 EEQ73092.1 - 3.4e-28 99.0 0.0 4e-28 98.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEQ73092.1 - 4.9e-27 94.8 1.6 6.3e-27 94.5 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ73092.1 - 7e-13 48.6 1.0 9.1e-13 48.2 0.7 1.1 1 0 0 1 1 1 1 KR domain ATG16 PF08614.6 EEQ73094.1 - 4.6 7.0 64.1 1.7 8.4 1.8 4.8 1 1 1 4 4 4 0 Autophagy protein 16 (ATG16) Glyco_hydro_43 PF04616.9 EEQ73095.1 - 1.9e-13 50.1 0.2 5.5e-13 48.6 0.0 1.9 2 1 0 2 2 2 1 Glycosyl hydrolases family 43 CoA_transf_3 PF02515.12 EEQ73096.1 - 1.1e-51 174.7 0.0 1.6e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Pkinase PF00069.20 EEQ73100.1 - 2.4e-33 115.3 0.0 9.4e-32 110.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ73100.1 - 6.1e-12 45.1 0.0 2e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EEQ73100.1 - 6.9e-05 22.0 0.1 0.00012 21.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3435 PF11917.3 EEQ73102.1 - 3.2e-101 339.0 0.0 5.6e-88 295.4 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) CAF1A PF12253.3 EEQ73105.1 - 5.2e-26 90.5 5.1 5.2e-26 90.5 3.5 3.3 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A SprA-related PF12118.3 EEQ73105.1 - 0.027 13.8 17.6 0.055 12.7 12.2 1.5 1 0 0 1 1 1 0 SprA-related family PBP_sp32 PF07222.7 EEQ73105.1 - 0.25 10.4 15.6 0.61 9.2 10.8 1.8 1 0 0 1 1 1 0 Proacrosin binding protein sp32 MIP-T3 PF10243.4 EEQ73105.1 - 0.45 8.9 46.1 0.94 7.8 31.9 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SAPS PF04499.10 EEQ73105.1 - 0.71 8.4 10.8 1.1 7.8 7.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DDRGK PF09756.4 EEQ73105.1 - 2.8 7.2 46.1 5.5 6.3 32.0 1.4 1 0 0 1 1 1 0 DDRGK domain F-box-like PF12937.2 EEQ73106.1 - 0.036 13.7 0.2 0.11 12.2 0.1 1.9 1 0 0 1 1 1 0 F-box-like RIX1 PF08167.7 EEQ73107.1 - 0.0072 16.0 0.4 0.024 14.3 0.0 1.8 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis IPP-2 PF04979.9 EEQ73110.1 - 6.3e-10 39.4 10.2 1.3e-06 28.6 0.1 2.6 2 1 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) GAGA PF09237.6 EEQ73110.1 - 0.032 13.8 0.2 0.032 13.8 0.1 2.0 2 0 0 2 2 2 0 GAGA factor ERF PF04404.7 EEQ73110.1 - 1.2 8.6 6.2 3.9 6.9 4.3 1.8 1 0 0 1 1 1 0 ERF superfamily AMP-binding PF00501.23 EEQ73111.1 - 4.6e-57 193.3 0.0 1.3e-56 191.7 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme CRAL_TRIO PF00650.15 EEQ73112.1 - 2.4e-18 66.1 0.1 3.7e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EEQ73112.1 - 1.8e-07 31.1 0.0 5.7e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain P35 PF02331.10 EEQ73112.1 - 0.05 12.7 0.1 0.078 12.0 0.1 1.2 1 0 0 1 1 1 0 Apoptosis preventing protein DUF1546 PF07571.8 EEQ73113.1 - 3.2e-31 107.2 0.0 9.1e-31 105.8 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 EEQ73113.1 - 3.1e-26 91.0 0.1 7.9e-26 89.8 0.0 1.7 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EEQ73113.1 - 2e-05 24.6 0.2 6.9e-05 22.8 0.1 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEQ73113.1 - 0.0047 16.9 0.1 0.019 14.9 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EEQ73113.1 - 0.046 13.4 0.1 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 Bromodomain associated CENP-S PF15630.1 EEQ73113.1 - 0.078 13.1 0.1 0.22 11.7 0.1 1.7 1 0 0 1 1 1 0 Kinetochore component CENP-S TFIID-31kDa PF02291.10 EEQ73113.1 - 0.083 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit SAM_decarbox PF01536.11 EEQ73114.1 - 3.5e-86 288.9 0.1 9.3e-82 274.3 0.0 3.9 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase TAFII28 PF04719.9 EEQ73115.1 - 3.2e-21 74.9 0.0 6e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 hTAFII28-like protein conserved region DUF605 PF04652.11 EEQ73115.1 - 0.0021 17.5 23.1 0.0021 17.5 16.0 2.3 2 0 0 2 2 2 1 Vta1 like 60KD_IMP PF02096.15 EEQ73116.1 - 3.4e-24 85.6 0.0 6e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein TOM13 PF08219.6 EEQ73117.1 - 7.3e-32 108.9 0.0 9.2e-32 108.6 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 SEP PF08059.8 EEQ73118.1 - 1e-27 96.1 0.1 1.9e-27 95.3 0.1 1.4 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 EEQ73118.1 - 3e-14 52.8 0.0 4.9e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EEQ73118.1 - 4.7e-14 51.6 0.0 7.3e-14 51.0 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 EEQ73118.1 - 0.00094 18.9 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain ParA PF10609.4 EEQ73119.1 - 6.5e-32 109.2 1.8 4e-31 106.7 1.2 2.2 1 1 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EEQ73119.1 - 1.1e-11 44.5 0.0 9.1e-11 41.5 0.0 2.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EEQ73119.1 - 1e-06 28.0 0.0 3e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.1 EEQ73119.1 - 8.5e-05 22.5 0.0 0.00047 20.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EEQ73119.1 - 0.00091 18.6 0.1 0.0016 17.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EEQ73119.1 - 0.0012 18.0 0.6 0.0023 17.0 0.4 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase YhjQ PF06564.7 EEQ73119.1 - 0.0028 17.0 0.3 0.052 12.8 0.1 2.1 2 0 0 2 2 2 1 YhjQ protein ArgK PF03308.11 EEQ73119.1 - 0.016 14.0 0.7 0.023 13.4 0.5 1.2 1 0 0 1 1 1 0 ArgK protein AAA_26 PF13500.1 EEQ73119.1 - 0.029 13.9 0.1 0.44 10.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 EEQ73119.1 - 0.034 13.7 0.1 0.09 12.4 0.1 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase OrfB_Zn_ribbon PF07282.6 EEQ73119.1 - 0.18 11.4 0.6 0.4 10.3 0.4 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Endostatin PF06482.6 EEQ73119.1 - 0.83 8.9 4.8 0.45 9.8 1.4 1.7 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin KTI12 PF08433.5 EEQ73119.1 - 2.5 7.2 4.1 3.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DNA_ligase_IV PF11411.3 EEQ73120.1 - 0.18 11.6 0.7 0.45 10.3 0.0 2.0 2 0 0 2 2 2 0 DNA ligase IV COG2 PF06148.6 EEQ73121.1 - 2.5e-32 111.5 0.4 2.5e-32 111.5 0.3 1.9 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 EEQ73121.1 - 1e-06 28.5 3.1 2.1e-06 27.4 0.0 2.6 3 0 0 3 3 3 1 Vps51/Vps67 COG5 PF10392.4 EEQ73121.1 - 0.016 15.1 1.9 0.02 14.8 0.1 1.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Sec8_exocyst PF04048.9 EEQ73121.1 - 0.043 13.4 0.5 3.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain FlaC_arch PF05377.6 EEQ73121.1 - 0.11 12.3 1.7 5.9 6.8 0.2 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Ribosomal_L1 PF00687.16 EEQ73122.1 - 6.1e-35 120.5 0.2 1.1e-34 119.7 0.1 1.5 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family TarH PF02203.10 EEQ73122.1 - 0.051 13.4 0.6 0.19 11.5 0.2 1.8 2 0 0 2 2 2 0 Tar ligand binding domain homologue Tetraspannin PF00335.15 EEQ73123.1 - 1.1e-08 34.6 0.5 1.7e-08 34.0 0.4 1.2 1 0 0 1 1 1 1 Tetraspanin family LRR19-TM PF15176.1 EEQ73123.1 - 0.075 12.7 0.0 0.25 11.0 0.0 2.0 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain FtsX PF02687.16 EEQ73123.1 - 1.1 9.0 11.1 0.076 12.7 1.5 2.7 3 0 0 3 3 3 0 FtsX-like permease family Glyco_hydro_16 PF00722.16 EEQ73124.1 - 1.4e-07 30.9 0.3 5.5e-07 29.0 0.0 2.1 3 1 0 3 3 3 1 Glycosyl hydrolases family 16 NMT1 PF09084.6 EEQ73125.1 - 0.036 13.6 0.0 0.25 10.8 0.0 2.2 1 1 0 1 1 1 0 NMT1/THI5 like SRR1 PF07985.7 EEQ73126.1 - 0.00013 21.7 0.0 0.00028 20.7 0.0 1.6 1 0 0 1 1 1 1 SRR1 PQ-loop PF04193.9 EEQ73127.1 - 2.2e-18 65.5 4.5 5.5e-12 45.0 0.3 2.8 2 0 0 2 2 2 2 PQ loop repeat Histidinol_dh PF00815.15 EEQ73128.1 - 2.9e-27 95.3 1.4 6.6e-13 48.0 0.0 2.3 1 1 1 2 2 2 2 Histidinol dehydrogenase p450 PF00067.17 EEQ73129.1 - 5.2e-60 203.2 0.0 6.9e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_31 PF01055.21 EEQ73130.1 - 3.2e-148 494.2 4.2 4.1e-148 493.8 2.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EEQ73130.1 - 2.2e-23 81.8 0.1 6.4e-23 80.3 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like NDK PF00334.14 EEQ73131.1 - 3.6e-55 185.4 0.0 4.2e-55 185.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase FLILHELTA PF10306.4 EEQ73132.1 - 3.5e-28 97.4 0.0 5.4e-28 96.8 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 EEQ73132.1 - 0.001 19.3 0.6 0.0014 18.8 0.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Abhydrolase_3 PF07859.8 EEQ73133.1 - 2.1e-40 138.5 0.1 8e-23 81.1 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 EEQ73133.1 - 0.16 10.6 0.0 0.29 9.8 0.0 1.4 1 1 0 1 1 1 0 Carboxylesterase family MTHFR PF02219.12 EEQ73134.1 - 1e-97 326.7 0.0 1.4e-97 326.2 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase TGT PF01702.13 EEQ73135.1 - 5e-43 147.1 0.0 6.4e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thymidylate_kin PF02223.12 EEQ73136.1 - 1.5e-45 154.8 0.0 1.8e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.5 EEQ73136.1 - 0.0018 17.5 0.0 0.0047 16.1 0.0 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_28 PF13521.1 EEQ73136.1 - 0.0053 16.7 0.0 0.0073 16.2 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEQ73136.1 - 0.051 13.8 0.0 0.45 10.8 0.0 2.2 1 1 0 2 2 2 0 AAA domain GIY-YIG PF01541.19 EEQ73137.1 - 9.9e-08 32.2 0.0 2.1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.3 EEQ73137.1 - 0.00072 19.4 4.4 0.0014 18.5 3.0 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 EEQ73137.1 - 0.023 14.3 6.4 0.05 13.2 4.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) KAR9 PF08580.5 EEQ73138.1 - 0.00021 19.7 0.2 0.00021 19.7 0.2 1.0 1 0 0 1 1 1 1 Yeast cortical protein KAR9 PLU-1 PF08429.6 EEQ73139.1 - 6.1e-109 363.9 17.6 5.3e-107 357.5 11.8 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 EEQ73139.1 - 1.3e-43 147.8 0.2 3.3e-43 146.5 0.2 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 EEQ73139.1 - 2.2e-26 91.5 0.0 5.4e-26 90.2 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 EEQ73139.1 - 3.8e-18 64.7 3.3 8.3e-18 63.6 2.3 1.6 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 EEQ73139.1 - 9.2e-16 57.6 9.3 2e-15 56.5 6.4 1.6 1 0 0 1 1 1 1 C5HC2 zinc finger PHD PF00628.24 EEQ73139.1 - 3.2 7.4 9.1 4.1 7.1 1.4 2.9 2 0 0 2 2 2 0 PHD-finger DHHA2 PF02833.9 EEQ73140.1 - 3.2e-12 46.7 0.0 7.7e-12 45.5 0.0 1.6 1 1 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EEQ73140.1 - 1.1e-06 28.3 0.0 3.6e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 DHH family Transglut_core PF01841.14 EEQ73141.1 - 1.6e-10 41.2 0.1 3.8e-10 39.9 0.1 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.12 EEQ73141.1 - 8.4e-08 31.5 0.2 2.2e-07 30.2 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEQ73141.1 - 1.5e-06 27.4 1.6 9.6e-06 24.8 0.0 2.5 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EEQ73141.1 - 2.6e-05 23.7 1.4 3.3e-05 23.3 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain IF-2B PF01008.12 EEQ73142.1 - 3.5e-23 81.9 0.0 5.4e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family RNase_H PF00075.19 EEQ73142.1 - 0.056 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 RNase H HDA2-3 PF11496.3 EEQ73143.1 - 2.8e-36 124.8 0.0 2.8e-36 124.8 0.0 2.3 2 2 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 WEMBL PF05701.6 EEQ73143.1 - 0.0053 15.2 36.6 0.011 14.2 25.4 1.5 1 1 0 1 1 1 1 Weak chloroplast movement under blue light CALCOCO1 PF07888.6 EEQ73143.1 - 1.1 7.5 38.0 1.7 6.8 26.3 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Reo_sigmaC PF04582.7 EEQ73143.1 - 1.3 8.0 11.4 3 6.9 1.0 2.5 1 1 0 2 2 2 0 Reovirus sigma C capsid protein CP12 PF02672.10 EEQ73143.1 - 1.4 9.3 8.2 2.6 8.5 0.3 3.5 2 1 1 3 3 3 0 CP12 domain WXG100 PF06013.7 EEQ73143.1 - 5.4 7.0 14.0 8.5 6.4 1.6 3.0 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Secretin_N_2 PF07655.8 EEQ73144.1 - 7 7.1 21.1 0.74 10.2 4.9 2.5 3 0 0 3 3 3 0 Secretin N-terminal domain FMO-like PF00743.14 EEQ73145.1 - 2.8e-46 157.8 0.0 1.5e-24 86.1 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EEQ73145.1 - 2.3e-14 53.9 0.1 1.3e-13 51.4 0.1 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEQ73145.1 - 3.8e-10 39.7 0.9 9.4e-09 35.2 0.2 3.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EEQ73145.1 - 1.3e-09 38.1 0.0 4.4e-08 33.2 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEQ73145.1 - 3e-09 36.2 0.1 1.9e-06 27.0 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EEQ73145.1 - 1.6e-08 34.4 0.0 4.6e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EEQ73145.1 - 5.3e-05 22.4 0.0 0.00091 18.3 0.0 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EEQ73145.1 - 0.00029 19.8 0.0 0.069 12.0 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EEQ73145.1 - 0.0033 15.9 0.0 0.038 12.4 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 EEQ73145.1 - 0.032 13.2 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Strep_67kDa_ant PF06100.6 EEQ73145.1 - 0.042 12.1 0.1 1.2 7.3 0.0 2.1 2 0 0 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Pyr_redox PF00070.22 EEQ73145.1 - 0.063 13.6 0.2 0.29 11.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEQ73145.1 - 0.085 11.6 0.0 1.5 7.5 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain 6PGD PF00393.14 EEQ73146.1 - 3.5e-65 220.1 0.0 5.3e-65 219.5 0.0 1.3 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EEQ73146.1 - 4.7e-31 107.8 0.0 7.9e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EEQ73146.1 - 7.8e-06 25.6 0.0 1.7e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EEQ73146.1 - 7.1e-05 22.5 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EEQ73146.1 - 0.011 14.9 0.3 0.072 12.2 0.0 2.3 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EEQ73146.1 - 0.014 14.8 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EEQ73146.1 - 0.048 13.0 0.0 0.3 10.4 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 EEQ73146.1 - 0.062 13.7 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AP_endonuc_2 PF01261.19 EEQ73147.1 - 2.5e-31 108.6 0.0 3.4e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel POT1 PF02765.12 EEQ73148.1 - 1.5e-20 73.6 0.0 2.8e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Peptidase_M19 PF01244.16 EEQ73149.1 - 5.2e-109 364.0 0.0 6e-109 363.8 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) AMP-binding PF00501.23 EEQ73150.1 - 4.5e-63 213.0 0.0 5.6e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ73150.1 - 1.3e-06 29.2 0.0 3e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GST_N_3 PF13417.1 EEQ73151.1 - 8e-07 29.1 0.0 1.8e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEQ73151.1 - 5e-06 26.4 0.0 9.1e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEQ73151.1 - 0.00011 22.0 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EEQ73151.1 - 0.00039 20.3 0.0 0.00068 19.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Aminotran_1_2 PF00155.16 EEQ73152.1 - 7.8e-30 104.0 0.0 9.4e-30 103.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EEQ73152.1 - 0.0001 21.5 0.0 0.00015 20.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase IF4E PF01652.13 EEQ73154.1 - 2.2e-51 173.6 0.0 3.3e-51 173.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Peptidase_C48 PF02902.14 EEQ73155.1 - 3e-31 108.7 0.0 1.4e-30 106.5 0.0 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SPC22 PF04573.7 EEQ73156.1 - 1.9e-33 115.1 0.5 9.5e-24 83.5 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit DUF4006 PF13179.1 EEQ73156.1 - 1.2 8.7 3.4 0.54 9.8 0.6 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF4006) Pmp3 PF01679.12 EEQ73157.1 - 4.2e-21 74.3 9.9 5.6e-21 73.9 6.9 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator BCDHK_Adom3 PF10436.4 EEQ73159.1 - 2.2e-46 157.3 0.1 1.1e-45 155.0 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EEQ73159.1 - 9.9e-10 38.1 0.0 1.1e-08 34.7 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EEQ73159.1 - 0.0089 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FAE1_CUT1_RppA PF08392.7 EEQ73160.1 - 0.13 11.3 0.4 0.55 9.2 0.0 1.9 2 0 0 2 2 2 0 FAE1/Type III polyketide synthase-like protein DUF1118 PF06549.7 EEQ73160.1 - 1.2 9.2 5.1 0.37 10.9 1.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1118) A_deaminase PF00962.17 EEQ73161.1 - 7.6e-40 136.8 0.0 1.9e-39 135.5 0.0 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase HET PF06985.6 EEQ73162.1 - 1.7e-33 115.7 0.0 3.4e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) USP7_ICP0_bdg PF12436.3 EEQ73163.1 - 2.9e-88 295.3 0.1 5e-87 291.2 0.0 2.2 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EEQ73163.1 - 3e-67 226.1 0.7 2e-64 216.9 0.2 2.9 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 EEQ73163.1 - 9.6e-52 175.7 0.2 1.6e-51 175.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEQ73163.1 - 1.4e-30 106.7 0.0 2.3e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EEQ73163.1 - 4.1e-11 43.1 0.0 1.6e-10 41.2 0.0 2.0 1 0 0 1 1 1 1 MATH domain Rad60-SLD PF11976.3 EEQ73163.1 - 0.029 14.0 0.3 51 3.6 0.0 4.0 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like EMP24_GP25L PF01105.19 EEQ73164.1 - 1.6e-46 158.3 0.1 1.8e-46 158.1 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD HeLo PF14479.1 EEQ73166.1 - 1.8e-23 83.3 1.2 3e-23 82.6 0.8 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Ank_2 PF12796.2 EEQ73167.1 - 5.1e-27 94.0 0.0 1.2e-09 38.4 0.0 5.3 4 2 1 5 5 5 4 Ankyrin repeats (3 copies) Pkinase PF00069.20 EEQ73167.1 - 4.9e-22 78.3 0.0 1e-21 77.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ73167.1 - 7.5e-17 61.2 0.0 1.2e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank PF00023.25 EEQ73167.1 - 9.3e-14 50.4 25.8 0.0061 16.3 0.0 9.5 10 0 0 10 10 10 5 Ankyrin repeat Ank_3 PF13606.1 EEQ73167.1 - 2.1e-13 49.0 11.7 0.024 14.8 0.0 9.5 10 0 0 10 10 10 2 Ankyrin repeat Ank_4 PF13637.1 EEQ73167.1 - 2.7e-12 46.8 2.1 0.0044 17.5 0.1 7.4 6 3 3 9 9 9 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ73167.1 - 1.2e-10 41.3 5.3 0.18 12.0 0.0 7.3 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Sel1 PF08238.7 EEQ73167.1 - 0.024 15.2 0.1 0.066 13.8 0.1 1.9 1 0 0 1 1 1 0 Sel1 repeat DUF4066 PF13278.1 EEQ73168.1 - 9.5e-07 28.2 0.7 1.4e-05 24.4 0.5 2.5 1 1 0 1 1 1 1 Putative amidotransferase CTD_bind PF04818.8 EEQ73169.1 - 6.2e-05 23.1 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II-binding domain. U79_P34 PF03064.11 EEQ73171.1 - 0.02 14.4 2.8 0.026 14.0 1.9 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Helicase_C_3 PF13625.1 EEQ73172.1 - 2.2e-25 88.8 0.0 8.8e-25 86.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ73172.1 - 8.4e-15 55.0 0.0 1.6e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EEQ73172.1 - 1.3e-12 47.3 0.0 2.9e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EEQ73172.1 - 1.9e-12 46.5 0.2 3.2e-12 45.8 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EEQ73172.1 - 5.4e-07 29.2 0.0 1.3e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_34 PF13872.1 EEQ73172.1 - 0.0016 17.2 0.1 0.0027 16.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DUF4243 PF14027.1 EEQ73173.1 - 4.5e-100 335.3 0.1 5.8e-100 334.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Dynamin_N PF00350.18 EEQ73174.1 - 1.4e-22 80.2 0.0 3.2e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EEQ73174.1 - 2.1e-12 46.4 0.0 4.8e-11 41.9 0.0 2.6 2 1 0 3 3 3 1 Dynamin central region MMR_HSR1 PF01926.18 EEQ73174.1 - 2.4e-05 24.2 0.0 0.00011 22.1 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEQ73174.1 - 0.13 11.5 0.1 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B NUDIX PF00293.23 EEQ73177.1 - 9.6e-17 60.8 0.1 1.8e-16 60.0 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 EEQ73177.1 - 3.7e-16 59.2 0.0 8e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EEQ73177.1 - 0.00028 20.3 0.8 0.00057 19.3 0.6 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Pkinase PF00069.20 EEQ73178.1 - 9.9e-72 241.2 0.0 2e-71 240.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ73178.1 - 2.9e-33 115.0 0.0 4.8e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ73178.1 - 0.00032 19.7 0.1 0.0022 17.0 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 EEQ73178.1 - 0.00055 19.0 0.2 0.0011 18.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3852 PF12963.2 EEQ73179.1 - 0.051 13.6 0.1 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3852) GTP_cyclohydroI PF01227.17 EEQ73180.1 - 4e-73 244.5 0.3 5.3e-73 244.1 0.2 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EEQ73180.1 - 0.0025 17.7 0.0 0.0049 16.7 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein WD40 PF00400.27 EEQ73181.1 - 2.4e-41 138.1 5.6 3.7e-08 32.9 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EEQ73181.1 - 1.1e-29 102.1 0.7 2.3e-29 101.1 0.5 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex XRN_N PF03159.13 EEQ73182.1 - 3.1e-102 341.0 0.1 3.1e-102 341.0 0.0 1.5 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus ACT_7 PF13840.1 EEQ73184.1 - 3e-22 77.8 0.2 6.4e-16 57.6 0.0 3.2 3 0 0 3 3 3 3 ACT domain YodL PF14191.1 EEQ73184.1 - 0.062 13.7 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 YodL-like Ail_Lom PF06316.6 EEQ73184.1 - 0.074 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Enterobacterial Ail/Lom protein WD40 PF00400.27 EEQ73185.1 - 1e-28 98.1 10.0 5e-07 29.3 0.2 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat PQQ_3 PF13570.1 EEQ73185.1 - 0.017 15.4 0.3 25 5.3 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain VID27 PF08553.5 EEQ73185.1 - 0.17 10.0 0.2 0.31 9.2 0.0 1.5 2 0 0 2 2 2 0 VID27 cytoplasmic protein Septin PF00735.13 EEQ73186.1 - 1.2e-114 382.1 0.1 1.2e-114 382.1 0.1 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EEQ73186.1 - 2.1e-07 30.8 0.0 4.1e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEQ73186.1 - 3.6e-06 26.5 0.1 7.9e-05 22.1 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EEQ73186.1 - 2.5e-05 23.5 0.0 7.5e-05 21.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 IIGP PF05049.8 EEQ73186.1 - 0.0011 17.8 0.0 0.0022 16.8 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.1 EEQ73186.1 - 0.003 17.1 0.1 0.006 16.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EEQ73186.1 - 0.0031 18.0 0.0 0.0093 16.4 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 EEQ73186.1 - 0.0041 17.2 0.4 0.013 15.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain AIG1 PF04548.11 EEQ73186.1 - 0.0046 16.0 0.0 0.0085 15.2 0.0 1.5 1 0 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.13 EEQ73186.1 - 0.011 15.1 0.1 0.032 13.7 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family Pox_A32 PF04665.7 EEQ73186.1 - 0.016 14.5 0.1 0.028 13.7 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Ras PF00071.17 EEQ73186.1 - 0.024 14.0 0.4 0.072 12.4 0.2 1.8 1 1 0 1 1 1 0 Ras family Dynamin_N PF00350.18 EEQ73186.1 - 0.038 13.8 6.1 0.82 9.4 0.0 3.1 2 1 1 3 3 3 0 Dynamin family T2SE PF00437.15 EEQ73186.1 - 0.039 12.8 0.3 0.088 11.6 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.22 EEQ73186.1 - 0.04 14.2 0.2 0.23 11.7 0.0 2.2 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.7 EEQ73186.1 - 0.041 13.5 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 EEQ73186.1 - 0.05 13.5 0.9 0.26 11.2 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain ArgK PF03308.11 EEQ73186.1 - 0.059 12.1 2.8 0.29 9.8 0.0 2.6 3 0 0 3 3 3 0 ArgK protein PduV-EutP PF10662.4 EEQ73186.1 - 0.074 12.5 0.3 2.9 7.3 0.2 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.9 EEQ73186.1 - 0.13 11.2 2.6 0.28 10.1 1.8 1.7 1 1 0 1 1 1 0 KAP family P-loop domain ATP_bind_1 PF03029.12 EEQ73186.1 - 0.14 11.6 0.7 9.5 5.6 0.1 2.5 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 EEQ73186.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase WD40 PF00400.27 EEQ73187.1 - 1.1e-51 170.8 26.9 1.3e-11 43.9 0.4 12.2 12 0 0 12 12 12 8 WD domain, G-beta repeat Utp12 PF04003.7 EEQ73187.1 - 3.3e-26 91.3 0.0 5.4e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EEQ73187.1 - 9.8e-08 31.9 4.0 0.012 15.2 0.1 6.4 6 2 1 7 7 7 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EEQ73187.1 - 0.00021 19.5 4.6 0.37 8.8 0.0 4.4 2 1 2 4 4 4 3 Nucleoporin Nup120/160 SKIP_SNW PF02731.10 EEQ73188.1 - 1.2e-67 226.2 5.5 1.2e-67 226.2 3.8 2.4 2 0 0 2 2 2 1 SKIP/SNW domain FAM60A PF15396.1 EEQ73188.1 - 2 8.0 12.7 4.6 6.9 8.8 1.6 1 0 0 1 1 1 0 Protein Family FAM60A TFIIA PF03153.8 EEQ73189.1 - 1.5 8.6 24.5 1.6 8.5 17.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3395 PF11875.3 EEQ73190.1 - 1.4e-39 135.1 0.0 2.1e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 EEQ73190.1 - 1.6e-14 53.3 0.8 3e-14 52.5 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain NAAA-beta PF15508.1 EEQ73191.1 - 2.9e-24 85.2 0.1 1.4e-23 83.0 0.0 2.0 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Spore_coat_CotO PF14153.1 EEQ73191.1 - 0.31 10.4 3.6 0.54 9.6 2.5 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Fungal_trans PF04082.13 EEQ73192.1 - 4.8e-13 48.5 0.3 1.4e-12 47.0 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ73192.1 - 8.5e-07 28.7 11.5 1.6e-06 27.9 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MGDG_synth PF06925.6 EEQ73192.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase Ribosomal_L4 PF00573.17 EEQ73193.1 - 2.4e-41 141.2 0.1 3.4e-41 140.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EEQ73193.1 - 6.4e-29 99.6 1.0 1.4e-28 98.5 0.7 1.6 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain Glyco_hydro_61 PF03443.9 EEQ73194.1 - 0.034 13.9 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 ToxN_toxin PF13958.1 EEQ73197.1 - 0.024 14.2 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Toxin ToxN, type III toxin-antitoxin system PC4 PF02229.11 EEQ73199.1 - 0.035 13.3 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) AMP-binding PF00501.23 EEQ73200.1 - 4.5e-35 120.8 0.0 1.1e-34 119.5 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ73200.1 - 0.009 16.9 0.0 0.022 15.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain UPF0029 PF01205.14 EEQ73201.1 - 2.8e-32 110.6 0.0 4.3e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EEQ73201.1 - 1.2e-05 25.1 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 RWD domain Aminotran_1_2 PF00155.16 EEQ73202.1 - 6.9e-10 38.4 0.0 2.2e-09 36.7 0.0 1.7 2 1 0 2 2 2 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EEQ73202.1 - 0.2 10.1 0.0 0.34 9.4 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase LCCL PF03815.14 EEQ73203.1 - 6.6e-14 51.6 0.1 1e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 LCCL domain PTR2 PF00854.16 EEQ73206.1 - 7.6e-43 146.7 8.1 1.9e-42 145.3 5.6 1.8 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 EEQ73206.1 - 3.3e-11 42.5 13.6 1.6e-10 40.2 9.2 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 EEQ73207.1 - 1.2e-15 57.1 0.1 2.5e-15 56.0 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF2489 PF10675.4 EEQ73207.1 - 0.064 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) Aminotran_3 PF00202.16 EEQ73208.1 - 2.2e-95 319.3 0.0 2.7e-95 319.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF296 PF03479.10 EEQ73208.1 - 0.09 12.4 0.1 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF296) Fungal_trans_2 PF11951.3 EEQ73209.1 - 0.0075 14.9 0.8 0.011 14.3 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain 2-Hacid_dh PF00389.25 EEQ73210.1 - 1.5e-08 34.1 0.0 2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.14 EEQ73210.1 - 0.006 15.7 0.0 0.047 12.8 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Asparaginase PF00710.15 EEQ73211.1 - 1.3e-102 342.8 0.0 1.6e-102 342.5 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 EEQ73211.1 - 4e-13 49.5 0.4 7.2e-13 48.6 0.3 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEQ73211.1 - 2.2e-10 40.7 1.8 1.2e-05 25.6 0.2 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EEQ73211.1 - 2.6e-10 39.5 4.6 1.4e-05 24.6 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EEQ73211.1 - 1.9e-08 34.2 2.7 1.1e-07 31.8 0.1 3.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ73211.1 - 1.7e-05 24.5 3.7 0.083 13.1 0.1 3.9 4 0 0 4 4 4 2 Ankyrin repeat MTTB PF06253.6 EEQ73211.1 - 0.11 10.1 0.3 0.2 9.3 0.2 1.3 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) ADH_zinc_N PF00107.21 EEQ73212.1 - 8.1e-28 96.5 0.4 1.3e-27 95.9 0.3 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEQ73212.1 - 6.2e-17 62.6 0.1 1.3e-16 61.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEQ73212.1 - 2.1e-08 33.8 0.0 1.1e-07 31.5 0.0 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EEQ73212.1 - 0.002 17.7 0.1 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EEQ73212.1 - 0.049 13.6 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ELFV_dehydrog PF00208.16 EEQ73212.1 - 0.064 12.8 1.0 0.14 11.7 0.2 1.8 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CMAS PF02353.15 EEQ73212.1 - 0.085 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF2783 PF10932.3 EEQ73213.1 - 0.0064 15.9 0.9 0.16 11.4 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2783) Ribosomal_S7e PF01251.13 EEQ73213.1 - 0.012 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S7e PilJ PF13675.1 EEQ73213.1 - 0.1 12.9 0.1 0.14 12.4 0.1 1.2 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1675 PF07897.6 EEQ73217.1 - 3.3 7.5 12.8 0.59 9.9 6.1 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1675) MgtE_N PF03448.12 EEQ73218.1 - 0.014 15.7 0.1 0.02 15.1 0.0 1.3 1 0 0 1 1 1 0 MgtE intracellular N domain ThylakoidFormat PF11264.3 EEQ73218.1 - 0.038 13.6 0.1 0.046 13.3 0.0 1.1 1 0 0 1 1 1 0 Thylakoid formation protein PRANC PF09372.5 EEQ73218.1 - 0.07 13.1 0.4 0.1 12.5 0.2 1.2 1 0 0 1 1 1 0 PRANC domain Pkinase PF00069.20 EEQ73219.1 - 0.0026 16.9 0.0 0.0073 15.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 EEQ73219.1 - 0.014 15.0 0.0 0.034 13.7 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 EEQ73219.1 - 0.11 12.1 0.0 0.11 12.1 0.0 2.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Flagellin_C PF00700.16 EEQ73219.1 - 0.37 10.9 7.2 0.57 10.3 3.2 2.5 2 1 1 3 3 3 0 Bacterial flagellin C-terminal helical region ERM PF00769.14 EEQ73219.1 - 1.4 8.4 23.5 2.6 7.5 13.1 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Exonuc_VII_L PF02601.10 EEQ73219.1 - 4.2 6.4 12.9 0.53 9.4 5.7 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit NmrA PF05368.8 EEQ73220.1 - 2.2e-64 216.8 0.0 2.9e-64 216.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEQ73220.1 - 0.0055 16.7 0.0 0.0092 15.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Pkinase PF00069.20 EEQ73221.1 - 2.5e-18 66.1 0.0 4.6e-18 65.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ73221.1 - 0.037 13.0 0.2 0.083 11.9 0.1 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase DUF1383 PF07134.6 EEQ73221.1 - 0.041 12.7 0.0 0.06 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1383) Ceramidase_alk PF04734.8 EEQ73222.1 - 0.0051 14.7 0.1 0.0057 14.6 0.1 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase NAP PF00956.13 EEQ73225.1 - 6.3e-18 64.7 5.6 6.3e-18 64.7 3.9 2.9 2 1 0 2 2 2 1 Nucleosome assembly protein (NAP) Syntaxin-6_N PF09177.6 EEQ73226.1 - 5.3e-26 90.8 0.4 1.1e-24 86.6 0.0 2.3 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EEQ73226.1 - 6.6e-13 48.1 8.9 9.4e-13 47.6 2.7 2.8 3 0 0 3 3 3 1 SNARE domain THOC7 PF05615.8 EEQ73226.1 - 0.0061 16.8 3.0 0.14 12.3 0.0 2.1 2 0 0 2 2 2 1 Tho complex subunit 7 TBPIP PF07106.8 EEQ73226.1 - 0.04 13.4 1.4 0.59 9.6 0.0 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AKNA PF12443.3 EEQ73226.1 - 0.043 13.8 0.8 0.94 9.5 0.0 2.3 2 0 0 2 2 2 0 AT-hook-containing transcription factor Myosin_tail_1 PF01576.14 EEQ73226.1 - 0.069 10.8 6.1 0.56 7.8 0.6 2.1 2 0 0 2 2 2 0 Myosin tail NPV_P10 PF05531.7 EEQ73226.1 - 0.13 12.5 1.2 3.4 7.9 0.1 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2072 PF09845.4 EEQ73226.1 - 0.21 11.5 1.5 0.48 10.3 0.1 2.0 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) DUF883 PF05957.8 EEQ73226.1 - 0.3 11.5 4.2 1.6 9.1 0.0 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Zwint PF15556.1 EEQ73226.1 - 0.41 9.8 6.7 1.7 7.8 2.3 2.1 2 0 0 2 2 2 0 ZW10 interactor Baculo_PEP_C PF04513.7 EEQ73226.1 - 0.44 10.3 2.8 4.3 7.1 0.3 2.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.1 EEQ73226.1 - 0.69 10.2 5.2 4 7.8 0.2 2.5 2 1 0 2 2 2 0 Snapin/Pallidin Tropomyosin_1 PF12718.2 EEQ73226.1 - 0.72 9.6 6.3 5 6.9 0.1 2.1 2 0 0 2 2 2 0 Tropomyosin like TMF_DNA_bd PF12329.3 EEQ73226.1 - 9.1 6.1 7.3 3.2 7.6 0.1 2.7 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Methyltransf_32 PF13679.1 EEQ73227.1 - 2.6e-19 69.3 0.3 4.9e-19 68.4 0.2 1.5 1 1 0 1 1 1 1 Methyltransferase domain Peptidase_S8 PF00082.17 EEQ73228.1 - 8e-41 140.0 0.5 1.2e-40 139.4 0.4 1.2 1 0 0 1 1 1 1 Subtilase family Orbi_VP3 PF01700.11 EEQ73228.1 - 0.011 13.1 0.0 0.017 12.6 0.0 1.1 1 0 0 1 1 1 0 Orbivirus VP3 (T2) protein Glyco_transf_15 PF01793.11 EEQ73229.1 - 7.8e-135 449.0 9.8 9.3e-135 448.8 6.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Spc97_Spc98 PF04130.8 EEQ73230.1 - 2.1e-64 217.7 12.8 3e-64 217.2 8.8 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 EEQ73230.1 - 0.012 13.7 0.5 1 7.4 0.1 2.3 2 0 0 2 2 2 0 gamma-Tubulin ring complex non-core subunit mod21 BTV_NS2 PF04514.7 EEQ73230.1 - 0.23 10.3 0.1 0.37 9.6 0.0 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 GATase_5 PF13507.1 EEQ73231.1 - 9.1e-99 329.5 0.0 1.4e-98 328.9 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EEQ73231.1 - 5.2e-45 153.1 0.4 1.5e-21 76.9 0.2 2.6 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EEQ73231.1 - 1.1e-26 92.8 0.0 1.9e-25 88.9 0.0 2.7 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Fungal_trans PF04082.13 EEQ73233.1 - 1.9e-07 30.2 0.9 6e-07 28.5 0.6 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ73233.1 - 1.7e-06 27.8 12.2 3.2e-06 26.9 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ded_cyto PF06920.8 EEQ73233.1 - 0.077 12.2 0.0 1 8.6 0.0 2.2 2 0 0 2 2 2 0 Dedicator of cytokinesis COX5A PF02284.11 EEQ73234.1 - 2.3e-38 130.4 0.5 3e-38 130.1 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va ELO PF01151.13 EEQ73235.1 - 1e-63 214.9 18.4 1.2e-63 214.7 12.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Diphtheria_R PF01324.14 EEQ73236.1 - 0.074 12.5 0.1 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Diphtheria toxin, R domain Ank_2 PF12796.2 EEQ73237.1 - 1.7e-06 28.2 0.0 3.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) AAA_16 PF13191.1 EEQ73237.1 - 1.9e-05 24.7 0.1 0.032 14.2 0.0 2.4 1 1 1 2 2 2 2 AAA ATPase domain Ank PF00023.25 EEQ73237.1 - 5.4e-05 22.7 0.0 0.1 12.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EEQ73237.1 - 0.0024 17.9 0.0 4.9 7.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EEQ73237.1 - 0.033 14.6 0.0 0.067 13.7 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) F-box PF00646.28 EEQ73241.1 - 0.00086 18.8 0.0 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EEQ73241.1 - 0.022 14.4 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 F-box-like Myb_DNA-bind_3 PF12776.2 EEQ73242.1 - 1.9e-09 38.0 6.2 3.2e-09 37.3 4.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Pyr_redox_2 PF07992.9 EEQ73243.1 - 3.8e-14 53.0 0.0 1.3e-13 51.2 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEQ73243.1 - 6.8e-11 42.4 0.0 1.1e-07 32.0 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEQ73243.1 - 3.2e-07 30.6 2.5 0.0063 16.6 0.0 3.6 2 2 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase CoA_binding_2 PF13380.1 EEQ73243.1 - 0.03 14.5 0.2 0.087 12.9 0.1 1.8 2 0 0 2 2 2 0 CoA binding domain Lycopene_cycl PF05834.7 EEQ73243.1 - 0.064 12.1 0.1 0.46 9.3 0.0 2.2 3 0 0 3 3 3 0 Lycopene cyclase protein Sugar_tr PF00083.19 EEQ73244.1 - 5e-75 252.7 25.5 5.9e-75 252.5 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ73244.1 - 6.2e-15 54.7 50.9 3.9e-12 45.5 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyclase PF04199.8 EEQ73245.1 - 2.1e-10 40.5 0.0 3e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Sigma70_ner PF04546.8 EEQ73248.1 - 0.00083 19.0 2.0 0.0011 18.6 1.4 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region RRN3 PF05327.6 EEQ73248.1 - 0.0048 15.0 2.7 0.0058 14.8 1.9 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Nro1 PF12753.2 EEQ73248.1 - 0.016 14.1 0.5 0.016 14.1 0.4 1.1 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 DUF506 PF04720.7 EEQ73248.1 - 0.071 12.7 0.3 0.091 12.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF506) PBP1_TM PF14812.1 EEQ73248.1 - 0.073 13.3 7.5 0.11 12.8 5.2 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 EEQ73248.1 - 0.089 12.3 6.3 0.03 13.8 2.8 1.5 2 0 0 2 2 2 0 Nucleoplasmin DUF688 PF05097.7 EEQ73248.1 - 0.1 11.5 1.5 0.12 11.2 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) CENP-B_dimeris PF09026.5 EEQ73248.1 - 0.11 12.7 6.9 0.14 12.3 4.8 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 EEQ73248.1 - 0.23 10.7 5.4 0.26 10.5 3.7 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 EEQ73248.1 - 2.4 6.7 15.1 3.2 6.3 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) G10 PF01125.12 EEQ73250.1 - 0.0043 16.6 0.0 1.6 8.2 0.0 2.4 1 1 2 3 3 3 2 G10 protein Phage_CI_repr PF07022.8 EEQ73253.1 - 0.034 14.2 0.0 5.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain TPP_enzyme_M PF00205.17 EEQ73253.1 - 0.086 12.5 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain adh_short_C2 PF13561.1 EEQ73254.1 - 1.6e-07 31.3 0.0 2.5e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1996 PF09362.5 EEQ73255.1 - 1.9e-80 269.9 0.1 2.3e-80 269.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CART PF06373.6 EEQ73256.1 - 0.14 12.1 0.4 0.34 10.8 0.2 1.7 1 1 0 1 1 1 0 Cocaine and amphetamine regulated transcript protein (CART) p450 PF00067.17 EEQ73257.1 - 3.6e-73 246.6 0.0 4.3e-73 246.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GED PF02212.13 EEQ73257.1 - 0.0052 16.6 0.0 0.017 15.0 0.0 1.8 2 0 0 2 2 2 1 Dynamin GTPase effector domain TPR_11 PF13414.1 EEQ73258.1 - 4.6e-30 103.0 15.3 2.4e-11 43.0 0.1 7.5 6 1 0 7 7 7 5 TPR repeat TPR_2 PF07719.12 EEQ73258.1 - 1.7e-28 96.2 11.3 0.00015 21.4 0.0 9.8 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ73258.1 - 8.7e-27 91.5 8.0 0.00022 20.6 0.4 9.2 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ73258.1 - 2.7e-19 68.8 21.7 5.1e-10 39.1 0.4 7.6 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ73258.1 - 4e-13 48.1 4.3 0.077 12.8 0.1 7.9 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ73258.1 - 6.7e-13 48.0 22.0 0.097 13.3 0.4 9.0 8 2 2 10 10 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ73258.1 - 8e-13 48.5 14.9 0.0055 17.0 0.2 6.9 7 1 2 9 9 9 4 Tetratricopeptide repeat Apc3 PF12895.2 EEQ73258.1 - 9e-12 44.9 9.6 4.1e-06 26.8 0.4 6.0 6 1 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EEQ73258.1 - 3.5e-11 43.4 30.0 0.0034 18.0 0.4 8.3 8 1 1 9 9 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ73258.1 - 2.3e-10 39.4 13.8 0.11 12.2 0.1 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ73258.1 - 1.4e-07 31.5 7.4 0.44 11.1 0.2 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ73258.1 - 6.3e-07 29.1 7.0 0.29 11.4 0.0 7.4 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.1 EEQ73258.1 - 1.3e-06 28.0 16.9 0.0019 18.0 0.1 6.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 EEQ73258.1 - 5.8e-06 26.2 15.7 0.038 14.4 1.4 7.6 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_21 PF09976.4 EEQ73258.1 - 0.042 13.7 5.8 16 5.4 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ73258.1 - 0.05 13.4 17.7 4.6 7.1 0.3 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat DUF572 PF04502.8 EEQ73259.1 - 5.5e-73 246.0 13.6 6.7e-73 245.7 9.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.8 EEQ73259.1 - 0.0039 16.7 0.2 0.0078 15.7 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) zinc_ribbon_5 PF13719.1 EEQ73259.1 - 0.016 14.8 0.9 10 5.8 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Benyvirus_14KDa PF07255.6 EEQ73259.1 - 0.019 14.8 0.2 0.035 13.9 0.1 1.3 1 0 0 1 1 1 0 Benyvirus 14KDa protein zinc_ribbon_4 PF13717.1 EEQ73259.1 - 0.025 14.2 1.3 9.7 5.9 0.0 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zf-FCS PF06467.9 EEQ73259.1 - 0.083 12.5 3.8 0.24 11.0 0.2 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-ribbon_3 PF13248.1 EEQ73259.1 - 0.11 11.7 0.3 0.54 9.5 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 EEQ73259.1 - 0.19 11.2 2.0 13 5.3 0.2 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit NAM-associated PF14303.1 EEQ73259.1 - 0.37 11.1 14.9 0.6 10.4 10.3 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain TF_Zn_Ribbon PF08271.7 EEQ73259.1 - 1.5 8.2 6.4 2.8 7.3 1.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding FAT PF02259.18 EEQ73260.1 - 3e-75 253.4 8.9 5.1e-75 252.6 6.2 1.4 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EEQ73260.1 - 1.2e-29 103.4 0.5 6.9e-29 100.9 0.2 2.3 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EEQ73260.1 - 8.8e-10 37.8 0.2 3.1e-09 36.1 0.2 2.0 1 0 0 1 1 1 1 FATC domain Collagen PF01391.13 EEQ73260.1 - 6e-05 22.5 14.5 6e-05 22.5 10.1 1.9 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) TPR_2 PF07719.12 EEQ73260.1 - 0.55 10.2 4.1 2.8 8.0 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat B56 PF01603.15 EEQ73261.1 - 9.3e-172 571.2 4.8 1.1e-171 570.9 3.3 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Tau95 PF09734.4 EEQ73262.1 - 5e-70 236.2 0.0 6.4e-70 235.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit MAM1 PF10434.4 EEQ73262.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex protein MAM1 Zip PF02535.17 EEQ73263.1 - 3 6.7 5.7 5 6.0 4.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter NAD_binding_9 PF13454.1 EEQ73264.1 - 0.1 12.3 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 FAD-NAD(P)-binding DUF3503 PF12011.3 EEQ73265.1 - 0.063 13.0 1.4 0.08 12.6 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3503) C_GCAxxG_C_C PF09719.5 EEQ73265.1 - 0.36 10.6 2.1 0.52 10.1 1.5 1.3 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) WD40 PF00400.27 EEQ73266.1 - 3.3e-60 197.9 30.1 9.2e-13 47.5 0.7 7.4 6 1 1 7 7 7 6 WD domain, G-beta repeat NACHT PF05729.7 EEQ73266.1 - 3.8e-24 85.2 0.2 7.8e-24 84.1 0.1 1.5 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.8 EEQ73266.1 - 1.7e-05 24.5 0.0 3.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein AAA_16 PF13191.1 EEQ73266.1 - 3.2e-05 23.9 0.3 0.0002 21.4 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEQ73266.1 - 3.6e-05 23.9 0.1 0.00033 20.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain DUF676 PF05057.9 EEQ73266.1 - 0.00017 20.9 0.0 0.00036 19.8 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_19 PF13245.1 EEQ73266.1 - 0.0042 16.7 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 EEQ73266.1 - 0.042 14.0 0.0 0.2 11.8 0.0 2.3 2 0 0 2 2 1 0 RNA helicase AAA PF00004.24 EEQ73266.1 - 0.069 13.3 0.0 0.32 11.2 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EEQ73266.1 - 0.09 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase Abhydrolase_5 PF12695.2 EEQ73266.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family PfkB PF00294.19 EEQ73271.1 - 1.3e-32 113.1 0.3 2.2e-20 72.9 0.2 3.2 3 0 0 3 3 3 3 pfkB family carbohydrate kinase Mucin PF01456.12 EEQ73271.1 - 0.29 10.9 17.2 0.62 9.8 11.9 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Tir_receptor_C PF07489.6 EEQ73271.1 - 0.56 9.9 7.8 1 9.0 5.4 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Dicty_REP PF05086.7 EEQ73271.1 - 0.82 7.3 4.0 1.1 6.9 2.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 EEQ73271.1 - 1.1 7.1 12.6 1.6 6.5 8.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 EEQ73271.1 - 6.6 6.5 14.1 14 5.4 9.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ECH PF00378.15 EEQ73272.1 - 1.7e-38 132.1 0.1 1.5e-37 129.0 0.1 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family MFS_1 PF07690.11 EEQ73274.1 - 2e-30 105.6 41.8 4e-28 98.1 29.0 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MCM PF00493.18 EEQ73275.1 - 2.6e-143 476.7 0.1 3.4e-143 476.3 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EEQ73275.1 - 1.4e-18 67.5 0.5 3.5e-18 66.2 0.3 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEQ73275.1 - 1.1e-06 27.9 0.0 0.00019 20.6 0.0 2.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEQ73275.1 - 4.7e-05 23.1 0.0 0.0001 22.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EEQ73275.1 - 0.00092 18.8 0.1 0.0033 17.0 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 EEQ73275.1 - 0.011 16.1 0.5 0.028 14.8 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EEQ73275.1 - 0.026 14.0 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 EEQ73275.1 - 0.082 13.1 0.1 0.51 10.5 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Vps54 PF07928.7 EEQ73276.1 - 1.1e-48 164.7 0.5 3.1e-48 163.3 0.4 1.8 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 EEQ73276.1 - 1.7e-07 30.4 1.3 3.8e-07 29.3 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) LUC7 PF03194.10 EEQ73276.1 - 0.053 13.0 1.1 0.097 12.1 0.8 1.3 1 0 0 1 1 1 0 LUC7 N_terminus Glycogen_syn PF05693.8 EEQ73279.1 - 0 1123.6 0.0 0 1123.3 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_trans_4_4 PF13579.1 EEQ73279.1 - 3.7e-07 30.4 0.2 9.2e-07 29.1 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.15 EEQ73279.1 - 1e-06 28.2 0.0 0.0018 17.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Phospholip_A2_3 PF09056.6 EEQ73280.1 - 8.1e-43 145.1 3.9 9.9e-43 144.8 2.7 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 DUF2951 PF11166.3 EEQ73280.1 - 0.13 12.1 0.4 0.2 11.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) polyprenyl_synt PF00348.12 EEQ73281.1 - 6.3e-70 234.9 0.0 7.5e-70 234.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase APC8 PF04049.8 EEQ73282.1 - 1.3e-41 141.6 0.0 2.8e-41 140.5 0.0 1.6 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 EEQ73282.1 - 4.3e-22 76.7 1.7 0.00015 21.2 0.0 7.3 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ73282.1 - 7.6e-19 67.1 15.5 3.6e-07 29.7 0.1 6.9 6 2 2 8 8 8 4 TPR repeat TPR_8 PF13181.1 EEQ73282.1 - 8.6e-18 62.7 5.3 0.00031 20.3 0.0 6.9 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ73282.1 - 1.5e-17 62.0 17.8 0.15 12.0 0.0 9.7 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ73282.1 - 1.3e-13 51.2 19.3 5.2e-05 23.7 0.0 7.7 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ73282.1 - 1.1e-09 38.0 22.9 0.02 14.7 0.0 7.4 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ73282.1 - 3.5e-09 36.4 19.3 0.0056 17.1 0.0 8.6 8 3 3 11 11 8 4 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ73282.1 - 2.8e-08 32.9 7.3 0.49 10.3 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ73282.1 - 1.1e-07 32.1 10.5 0.65 10.3 0.0 7.3 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ73282.1 - 3.7e-07 30.1 20.4 0.73 10.4 0.2 9.7 10 1 0 10 10 9 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ73282.1 - 6.7e-07 29.0 7.2 2.5 8.5 0.0 6.9 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ73282.1 - 6.3e-06 25.9 11.2 0.0021 17.8 0.4 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EEQ73282.1 - 8.6e-05 22.5 12.5 0.23 11.6 0.1 4.8 6 0 0 6 6 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EEQ73282.1 - 0.00031 19.9 9.6 0.0014 17.7 2.3 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EEQ73282.1 - 0.12 12.3 18.5 10 6.1 0.3 7.0 8 1 1 9 9 9 0 Tetratricopeptide repeat BAR_2 PF10455.4 EEQ73282.1 - 0.17 10.7 0.0 0.32 9.8 0.0 1.4 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DNA_ligase_A_M PF01068.16 EEQ73283.1 - 1.9e-27 95.9 0.1 3.1e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EEQ73283.1 - 4.3e-15 55.9 0.0 8.4e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus TORC_M PF12885.2 EEQ73283.1 - 0.0093 15.7 4.7 0.02 14.6 3.3 1.5 1 0 0 1 1 1 1 Transducer of regulated CREB activity middle domain DUF3449 PF11931.3 EEQ73284.1 - 9.5e-68 227.5 1.1 1.3e-67 227.0 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 EEQ73284.1 - 5.8e-15 54.5 0.6 1.3e-14 53.4 0.4 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 EEQ73284.1 - 2.6e-08 33.8 1.1 1.1e-06 28.5 0.4 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EEQ73284.1 - 1.6e-07 31.2 3.1 4.7e-07 29.7 0.3 2.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EEQ73284.1 - 0.00078 19.5 0.1 0.016 15.3 0.0 2.6 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF951 PF06107.6 EEQ73284.1 - 0.075 12.5 0.0 0.25 10.8 0.0 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) zf-DBF PF07535.7 EEQ73284.1 - 0.83 9.3 3.4 0.9 9.2 0.2 2.7 3 0 0 3 3 3 0 DBF zinc finger DUF4375 PF14300.1 EEQ73284.1 - 1 9.3 6.8 3.5 7.6 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4375) DEAD PF00270.24 EEQ73285.1 - 2.5e-40 137.7 0.4 5.4e-40 136.6 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ73285.1 - 2.7e-29 100.8 0.2 5.6e-29 99.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EEQ73285.1 - 0.0032 17.1 0.1 0.0073 16.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EEQ73285.1 - 0.013 15.0 0.2 0.03 13.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 EEQ73285.1 - 0.023 14.5 0.1 0.052 13.3 0.1 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EEQ73285.1 - 0.037 13.7 0.2 0.13 12.0 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain tRNA-synt_1b PF00579.20 EEQ73285.1 - 0.1 11.7 0.0 0.24 10.4 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) AAA_22 PF13401.1 EEQ73285.1 - 0.1 12.7 0.9 0.5 10.5 0.6 2.1 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 EEQ73285.1 - 0.11 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_11 PF13086.1 EEQ73285.1 - 0.12 11.9 0.3 0.16 11.5 0.2 1.5 1 1 0 1 1 1 0 AAA domain WD40 PF00400.27 EEQ73286.1 - 6.9e-29 98.6 11.6 1.5e-05 24.6 0.3 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat CLTH PF10607.4 EEQ73286.1 - 0.00033 20.3 0.1 0.00057 19.5 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Nup160 PF11715.3 EEQ73286.1 - 0.0025 16.0 0.1 0.0055 14.8 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin Nup120/160 PD40 PF07676.7 EEQ73286.1 - 0.0033 17.0 0.1 6.5 6.5 0.0 3.9 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat ATP-synt_ab PF00006.20 EEQ73288.1 - 3.4e-114 379.7 0.0 4.7e-114 379.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EEQ73288.1 - 3.9e-17 62.7 0.6 7.5e-17 61.8 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EEQ73288.1 - 9.4e-15 54.5 2.2 2.1e-14 53.4 1.5 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain YccJ PF13993.1 EEQ73288.1 - 0.031 14.3 0.1 0.088 12.9 0.1 1.7 1 0 0 1 1 1 0 YccJ-like protein Dynamin_M PF01031.15 EEQ73289.1 - 7.7e-106 353.1 0.1 7.7e-106 353.1 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EEQ73289.1 - 1.1e-51 174.9 0.2 2.5e-51 173.8 0.1 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EEQ73289.1 - 9e-29 99.2 6.6 9e-29 99.2 4.6 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EEQ73289.1 - 3.9e-05 23.5 0.5 0.0003 20.7 0.3 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEQ73289.1 - 0.003 18.0 0.0 0.08 13.4 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein MHCassoc_trimer PF08831.5 EEQ73289.1 - 0.59 10.0 3.2 2.5 8.0 0.1 2.8 3 0 0 3 3 3 0 Class II MHC-associated invariant chain trimerisation domain BNIP3 PF06553.7 EEQ73290.1 - 0.0047 16.3 1.0 0.011 15.1 0.7 1.6 1 0 0 1 1 1 1 BNIP3 TrkH PF02386.11 EEQ73291.1 - 1.1e-117 392.5 11.2 9.7e-117 389.4 1.8 2.2 2 0 0 2 2 2 2 Cation transport protein adh_short PF00106.20 EEQ73292.1 - 2.9e-13 50.0 0.3 8.8e-13 48.5 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EEQ73292.1 - 4.5e-05 23.1 0.1 8.7e-05 22.2 0.0 1.5 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EEQ73292.1 - 0.00054 18.9 0.0 0.00072 18.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EEQ73292.1 - 0.1 12.7 0.1 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.12 EEQ73293.1 - 5.4e-49 166.6 0.0 2.1e-48 164.6 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EEQ73293.1 - 1e-23 84.0 0.0 1.3e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EEQ73293.1 - 3.9e-13 48.9 0.0 7.9e-10 38.0 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EEQ73293.1 - 3.9e-11 42.1 0.0 4.9e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EEQ73293.1 - 7.7e-10 38.1 0.4 2.4e-08 33.2 0.3 2.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EEQ73293.1 - 7.3e-07 29.3 0.4 1.1e-06 28.8 0.3 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EEQ73293.1 - 0.00011 22.2 0.7 0.00036 20.4 0.5 1.9 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EEQ73293.1 - 0.0013 18.0 0.1 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 EEQ73293.1 - 0.19 11.3 2.4 3 7.4 0.6 2.8 2 1 0 2 2 2 0 KR domain Rib_recp_KP_reg PF05104.7 EEQ73294.1 - 6.2 7.3 17.5 8.5 6.8 12.1 1.1 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region PH PF00169.24 EEQ73296.1 - 0.0054 16.9 0.1 0.014 15.6 0.1 1.6 1 0 0 1 1 1 1 PH domain DUF3431 PF11913.3 EEQ73297.1 - 1.6e-83 279.5 0.1 4.4e-83 278.1 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) Mito_fiss_reg PF05308.6 EEQ73297.1 - 0.27 10.5 9.2 0.48 9.7 6.4 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 EEQ73297.1 - 5.6 6.1 11.2 10 5.2 7.8 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SKG6 PF08693.5 EEQ73298.1 - 4.5e-07 29.0 1.1 1.2e-06 27.7 0.3 2.0 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF2881 PF11087.3 EEQ73299.1 - 0.019 14.4 3.5 15 5.1 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2881) DUF1801 PF08818.6 EEQ73300.1 - 0.058 13.4 0.0 0.085 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DU1801) F-box-like PF12937.2 EEQ73302.1 - 3.3e-09 36.3 2.7 9.8e-09 34.8 1.8 1.9 1 1 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EEQ73302.1 - 0.087 12.5 6.9 0.06 13.1 0.7 3.2 3 1 0 3 3 3 0 Leucine rich repeat F-box PF00646.28 EEQ73302.1 - 0.13 12.0 8.9 3.8 7.2 0.5 3.5 4 0 0 4 4 4 0 F-box domain LRR_4 PF12799.2 EEQ73302.1 - 3.3 7.4 10.6 9.9 5.9 0.1 3.9 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) zf-RanBP PF00641.13 EEQ73304.1 - 2.5e-20 71.2 8.3 7.1e-11 41.0 1.1 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 EEQ73304.1 - 3.5e-07 29.7 0.0 6.1e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 EEQ73304.1 - 3e-06 27.5 0.0 5.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_6 PF14259.1 EEQ73304.1 - 0.00015 21.6 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 EEQ73304.1 - 2.2 8.1 9.2 0.77 9.6 0.7 2.5 2 0 0 2 2 2 0 Double zinc ribbon Cnd3 PF12719.2 EEQ73305.1 - 1.4e-100 336.1 0.7 6.4e-100 333.9 0.1 2.2 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EEQ73305.1 - 2.1e-09 37.5 7.1 3.6e-05 23.9 0.2 5.0 4 2 2 6 6 6 3 HEAT repeats HEAT_EZ PF13513.1 EEQ73305.1 - 5e-06 26.8 4.1 0.0045 17.4 0.5 4.3 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.17 EEQ73305.1 - 7.2e-05 22.5 2.2 0.067 13.2 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat MMS19_N PF14500.1 EEQ73305.1 - 0.12 11.6 0.6 1.1 8.4 0.0 2.6 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II PALP PF00291.20 EEQ73306.1 - 8.4e-62 209.1 0.2 1e-61 208.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3425 PF11905.3 EEQ73307.1 - 3.4e-36 124.1 0.6 4.9e-36 123.6 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EEQ73307.1 - 0.039 13.9 7.6 0.069 13.1 5.2 1.3 1 0 0 1 1 1 0 bZIP transcription factor NAD_binding_10 PF13460.1 EEQ73308.1 - 9.9e-09 35.4 0.1 1.8e-08 34.6 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EEQ73308.1 - 0.0077 15.5 0.6 0.064 12.5 0.1 2.3 1 1 1 2 2 2 1 NmrA-like family Oxidored_molyb PF00174.14 EEQ73309.1 - 2.9e-53 179.7 0.0 5.2e-53 178.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EEQ73309.1 - 4.4e-26 91.0 0.3 3.2e-25 88.2 0.1 2.1 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain BNR PF02012.15 EEQ73309.1 - 0.19 11.6 1.6 0.78 9.8 0.1 2.9 2 0 0 2 2 2 0 BNR/Asp-box repeat Tim17 PF02466.14 EEQ73310.1 - 2.4e-50 169.8 6.2 2.4e-50 169.8 4.3 2.0 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF4048 PF13257.1 EEQ73311.1 - 2.2e-93 312.5 21.7 2.2e-93 312.5 15.0 3.3 3 1 0 3 3 3 1 Domain of unknown function (DUF4048) TPD52 PF04201.10 EEQ73311.1 - 0.017 14.8 0.4 0.036 13.7 0.3 1.5 1 0 0 1 1 1 0 Tumour protein D52 family Acetyltransf_7 PF13508.1 EEQ73312.1 - 1e-07 32.0 0.0 2.3e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEQ73312.1 - 2.7e-07 30.7 0.0 6.4e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEQ73312.1 - 5.6e-07 29.5 0.1 1.1e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EEQ73312.1 - 7.3e-05 22.6 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEQ73312.1 - 0.0037 17.1 0.0 0.01 15.7 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase p450 PF00067.17 EEQ73313.1 - 2.6e-65 220.7 0.0 3.4e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAA_19 PF13245.1 EEQ73313.1 - 0.085 12.6 0.0 0.65 9.7 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain Pkinase PF00069.20 EEQ73315.1 - 5.7e-71 238.7 0.0 8.2e-71 238.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ73315.1 - 2.4e-47 161.1 0.0 3.8e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ73315.1 - 5.6e-06 25.5 0.0 3e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEQ73315.1 - 0.014 15.1 0.0 1.7 8.3 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family FAD-oxidase_C PF02913.14 EEQ73316.1 - 4.9e-60 202.9 0.0 7.1e-60 202.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EEQ73316.1 - 5.8e-34 116.5 0.3 9.8e-34 115.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Proteasome PF00227.21 EEQ73317.1 - 4.7e-55 185.8 0.1 6.2e-55 185.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEQ73317.1 - 2.6e-13 49.0 0.1 2.6e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.7 EEQ73317.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) zf-CHY PF05495.7 EEQ73318.1 - 8.5e-13 48.2 16.6 1.1e-12 47.8 11.5 1.1 1 0 0 1 1 1 1 CHY zinc finger Tmemb_55A PF09788.4 EEQ73318.1 - 0.0063 15.6 5.4 0.0082 15.2 3.7 1.1 1 0 0 1 1 1 1 Transmembrane protein 55A DUF1451 PF07295.6 EEQ73318.1 - 0.18 11.5 5.5 0.29 10.8 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) Cytochrome_C7 PF14522.1 EEQ73318.1 - 0.45 10.1 13.5 0.68 9.6 9.4 1.3 1 0 0 1 1 1 0 Cytochrome c7 Zn-ribbon_8 PF09723.5 EEQ73318.1 - 0.46 10.4 12.9 0.96 9.4 5.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_3 PF14369.1 EEQ73318.1 - 1.5 8.8 11.6 0.77 9.8 4.9 2.5 1 1 1 2 2 2 0 zinc-finger HypA PF01155.14 EEQ73318.1 - 2.1 8.0 12.1 9.8 5.9 8.5 1.8 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Exo_endo_phos PF03372.18 EEQ73319.1 - 2e-18 67.2 1.3 2.8e-18 66.7 0.0 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family BBS2_Mid PF14783.1 EEQ73319.1 - 0.06 13.1 0.0 0.39 10.5 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 EEQ73319.1 - 0.4 10.6 5.6 0.35 10.8 1.1 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat 3HCDH_N PF02737.13 EEQ73320.1 - 1.4e-05 24.8 0.0 2.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CbiG_C PF01890.11 EEQ73321.1 - 0.035 14.3 0.3 0.06 13.6 0.2 1.4 1 1 0 1 1 1 0 Cobalamin synthesis G C-terminus DUF3861 PF12977.2 EEQ73321.1 - 0.16 12.0 1.0 0.32 11.1 0.4 1.7 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2313 PF10076.4 EEQ73322.1 - 0.018 14.4 0.1 0.023 14.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2313) HNH_2 PF13391.1 EEQ73323.1 - 6.9e-18 64.2 0.0 1.4e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease NMO PF03060.10 EEQ73324.1 - 1.5e-56 191.9 5.8 2e-56 191.5 4.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EEQ73324.1 - 8.2e-09 34.7 0.7 1.8e-08 33.7 0.5 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EEQ73324.1 - 0.0017 17.2 3.8 0.0033 16.3 1.6 1.8 1 1 0 2 2 2 1 FMN-dependent dehydrogenase ECH PF00378.15 EEQ73325.1 - 6.9e-49 166.1 0.0 9.1e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EEQ73325.1 - 0.057 13.1 0.0 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 Peptidase family S49 DUF2207 PF09972.4 EEQ73326.1 - 0.11 11.0 0.0 0.14 10.7 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Shisa PF13908.1 EEQ73326.1 - 2.2 8.4 12.4 1.1 9.4 5.9 2.2 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF2668 PF10873.3 EEQ73326.1 - 3 8.0 12.2 0.023 14.8 2.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2668) DUF2341 PF10102.4 EEQ73327.1 - 0.06 13.4 1.3 0.14 12.2 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2341) DUF3431 PF11913.3 EEQ73328.1 - 2.7e-92 308.2 0.0 4.3e-92 307.6 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) CoaE PF01121.15 EEQ73329.1 - 2.6e-40 137.7 0.0 1.6e-20 73.2 0.0 2.2 2 0 0 2 2 2 2 Dephospho-CoA kinase AAA_17 PF13207.1 EEQ73329.1 - 0.00038 21.2 0.1 0.00072 20.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEQ73329.1 - 0.011 15.6 0.0 0.14 12.0 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEQ73329.1 - 0.06 13.6 0.3 0.11 12.7 0.2 1.8 1 1 0 1 1 1 0 AAA domain Nop53 PF07767.6 EEQ73330.1 - 0.00016 20.7 3.3 0.00016 20.7 2.3 2.0 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) Cwf_Cwc_15 PF04889.7 EEQ73330.1 - 0.0047 16.6 8.3 0.0047 16.6 5.8 2.2 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein MPP6 PF10175.4 EEQ73330.1 - 0.2 12.0 3.6 1.4 9.3 0.0 3.0 3 0 0 3 3 3 0 M-phase phosphoprotein 6 CDC45 PF02724.9 EEQ73330.1 - 0.73 7.7 17.5 0.0098 13.9 6.6 1.7 2 0 0 2 2 2 0 CDC45-like protein DDHD PF02862.12 EEQ73330.1 - 1.4 8.6 7.6 2.7 7.7 0.1 2.1 2 0 0 2 2 2 0 DDHD domain zf-CHCC PF10276.4 EEQ73331.1 - 4.5e-16 58.4 1.9 4.5e-16 58.4 1.3 2.0 2 0 0 2 2 2 1 Zinc-finger domain UPF0047 PF01894.12 EEQ73332.1 - 7.6e-41 138.6 0.0 8.6e-41 138.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 GFA PF04828.9 EEQ73333.1 - 0.0062 16.4 0.2 0.012 15.5 0.1 1.5 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NUDIX_2 PF13869.1 EEQ73335.1 - 2.5e-82 274.8 0.0 2.9e-82 274.5 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Peptidase_M16_C PF05193.16 EEQ73337.1 - 1.8e-35 122.2 0.1 1.9e-22 79.8 0.0 3.5 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EEQ73337.1 - 2.1e-31 108.6 5.3 5.3e-22 78.1 0.9 3.3 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) DBR1 PF05011.8 EEQ73338.1 - 2e-47 160.7 0.0 3.9e-47 159.7 0.0 1.5 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EEQ73338.1 - 5.4e-07 29.2 1.1 9.2e-07 28.4 0.8 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2435 PF10363.4 EEQ73339.1 - 1.2e-27 95.6 0.9 2.3e-26 91.5 0.1 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 EEQ73339.1 - 1.1e-10 40.7 0.0 3.5e-10 39.1 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) Urb2 PF10441.4 EEQ73339.1 - 0.14 11.7 2.0 3.2 7.3 0.1 3.1 3 0 0 3 3 3 0 Urb2/Npa2 family DUF3221 PF11518.3 EEQ73340.1 - 0.095 12.3 1.4 0.14 11.8 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3221) Abhydrolase_9_N PF15420.1 EEQ73341.1 - 0.03 14.0 0.0 0.04 13.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Polysacc_deac_1 PF01522.16 EEQ73342.1 - 1.1e-27 96.1 0.0 1.9e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EEQ73342.1 - 0.00017 21.5 13.2 0.00035 20.4 9.2 1.5 1 0 0 1 1 1 1 Chitin recognition protein DUF4256 PF14066.1 EEQ73343.1 - 0.07 12.6 0.4 0.14 11.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4256) Clathrin PF00637.15 EEQ73344.1 - 4.8e-23 81.3 3.7 7.2e-20 71.0 2.4 2.8 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.3 EEQ73344.1 - 3.1e-20 71.7 0.2 6.9e-20 70.6 0.1 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_5 PF14634.1 EEQ73344.1 - 0.00022 20.8 7.2 0.00044 19.9 5.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EEQ73344.1 - 0.0008 19.1 8.3 0.0015 18.2 5.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEQ73344.1 - 0.0012 18.8 6.6 0.0024 17.8 4.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.1 EEQ73344.1 - 0.0041 16.7 0.3 0.031 13.9 0.0 2.5 2 0 0 2 2 2 1 TPR repeat Vps39_2 PF10367.4 EEQ73344.1 - 0.018 15.2 0.5 0.018 15.2 0.3 2.7 2 1 1 3 3 2 0 Vacuolar sorting protein 39 domain 2 zf-rbx1 PF12678.2 EEQ73344.1 - 0.02 15.0 3.3 0.038 14.1 2.3 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EEQ73344.1 - 0.034 13.8 5.9 0.065 12.9 4.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_14 PF13428.1 EEQ73344.1 - 0.041 14.5 0.0 2.5 8.9 0.0 3.5 4 0 0 4 4 2 0 Tetratricopeptide repeat zf-C3HC4 PF00097.20 EEQ73344.1 - 0.067 12.8 7.1 0.13 11.9 4.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Leuk-A4-hydro_C PF09127.6 EEQ73344.1 - 0.11 12.0 0.9 0.42 10.1 0.1 2.2 2 0 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal TPR_12 PF13424.1 EEQ73344.1 - 0.12 12.3 9.6 0.33 10.9 0.4 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ73344.1 - 0.14 12.1 0.1 0.14 12.1 0.1 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ73344.1 - 0.19 11.5 1.6 0.7 9.8 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-Apc11 PF12861.2 EEQ73344.1 - 0.22 11.3 0.8 0.61 9.9 0.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EEQ73344.1 - 0.96 9.3 5.1 2.4 8.1 3.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TPR_1 PF00515.23 EEQ73344.1 - 1.4 8.6 4.1 2.7 7.7 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_4 PF12799.2 EEQ73346.1 - 5.7e-33 111.9 30.7 3.9e-09 35.9 0.3 8.4 7 2 2 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEQ73346.1 - 1.7e-23 82.1 38.2 1.2e-09 37.8 0.2 6.8 4 1 2 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 EEQ73346.1 - 1.1e-12 46.1 32.2 0.087 12.9 0.0 11.8 11 1 1 12 12 12 6 Leucine Rich Repeat LRR_6 PF13516.1 EEQ73346.1 - 1.5e-06 27.6 26.6 0.25 11.5 0.1 9.7 9 0 0 9 9 9 3 Leucine Rich repeat LRR_9 PF14580.1 EEQ73346.1 - 7.7e-05 22.3 10.0 0.047 13.2 0.9 4.0 2 2 3 5 5 5 3 Leucine-rich repeat LRR_7 PF13504.1 EEQ73346.1 - 0.0064 16.4 42.0 1.2 9.6 0.1 11.2 12 0 0 12 12 12 3 Leucine rich repeat IPK PF03770.11 EEQ73347.1 - 2.5e-57 193.7 0.0 4.5e-57 192.8 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase MFS_1 PF07690.11 EEQ73348.1 - 6.2e-15 54.7 21.5 6.2e-15 54.7 14.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 EEQ73348.1 - 9.8e-06 24.9 1.0 9.8e-06 24.9 0.7 2.0 2 0 0 2 2 2 1 Nodulin-like DUF2975 PF11188.3 EEQ73348.1 - 3.5 7.3 10.2 5.3 6.7 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) ERCC4 PF02732.10 EEQ73349.1 - 1.7e-29 102.4 0.0 4.5e-29 101.0 0.0 1.8 2 0 0 2 2 2 1 ERCC4 domain ISAV_HA PF06215.6 EEQ73349.1 - 0.19 9.9 0.1 0.29 9.3 0.1 1.2 1 0 0 1 1 1 0 Infectious salmon anaemia virus haemagglutinin DDRGK PF09756.4 EEQ73349.1 - 0.79 9.0 15.4 1.7 8.0 10.7 1.5 1 0 0 1 1 1 0 DDRGK domain CAF-1_p150 PF11600.3 EEQ73349.1 - 4.2 6.6 29.3 0.17 11.2 15.7 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Glycos_transf_1 PF00534.15 EEQ73350.1 - 3.6e-29 101.3 0.3 1.6e-28 99.2 0.2 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EEQ73350.1 - 4.8e-09 36.1 0.0 0.0002 21.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EEQ73350.1 - 1.2e-07 31.9 0.1 1.7e-05 24.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EEQ73350.1 - 2.5e-07 30.9 1.2 3.3e-06 27.3 0.3 2.5 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EEQ73350.1 - 0.0007 19.8 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Kinesin PF00225.18 EEQ73351.1 - 1.1e-91 307.0 0.0 1.1e-91 307.0 0.0 3.1 2 0 0 2 2 2 1 Kinesin motor domain AAA_13 PF13166.1 EEQ73351.1 - 0.0013 17.2 21.7 0.0013 17.2 15.0 6.6 3 1 3 6 6 6 4 AAA domain Kdo PF06293.9 EEQ73353.1 - 0.0016 17.5 0.0 0.0033 16.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ73353.1 - 0.0069 16.1 0.1 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EEQ73353.1 - 0.018 14.1 0.0 0.035 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain HSDR_N_2 PF13588.1 EEQ73353.1 - 0.11 12.3 0.0 0.26 11.0 0.0 1.7 1 1 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Sad1_UNC PF07738.8 EEQ73355.1 - 5.2e-15 55.4 0.0 8.6e-08 32.0 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal WD40 PF00400.27 EEQ73356.1 - 3.1e-37 125.1 12.7 3.3e-10 39.4 0.2 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EEQ73356.1 - 1.6e-09 36.4 4.4 0.034 12.3 0.1 4.8 3 2 2 5 5 5 4 Nucleoporin Nup120/160 APG6 PF04111.7 EEQ73356.1 - 0.0012 17.9 0.2 0.0019 17.3 0.1 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 Nup54 PF13874.1 EEQ73356.1 - 0.038 13.6 0.2 0.17 11.5 0.1 2.0 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF1664 PF07889.7 EEQ73356.1 - 0.11 12.3 0.5 2.6 7.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CM_2 PF01817.16 EEQ73357.1 - 2e-08 34.2 0.1 7.6e-06 25.9 0.0 3.1 2 1 0 2 2 2 2 Chorismate mutase type II PdxA PF04166.7 EEQ73357.1 - 0.066 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA BCIP PF13862.1 EEQ73358.1 - 1.1e-71 240.3 0.1 1.6e-71 239.8 0.1 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein BNIP2 PF12496.3 EEQ73358.1 - 0.69 10.0 3.0 20 5.3 0.2 2.4 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Fungal_trans_2 PF11951.3 EEQ73362.1 - 7.7e-49 166.2 3.5 3e-48 164.3 2.4 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ73362.1 - 2.5e-05 24.0 4.4 5.4e-05 23.0 3.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.1 EEQ73363.1 - 1.2e-61 208.5 49.7 1.5e-61 208.2 34.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ73363.1 - 6.9e-25 87.3 41.5 8.9e-25 86.9 28.7 1.1 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.16 EEQ73363.1 - 0.35 10.7 0.0 0.35 10.7 0.0 3.5 3 0 0 3 3 3 0 Gram positive anchor Ring_hydroxyl_A PF00848.14 EEQ73365.1 - 1.2e-32 113.2 3.6 4.2e-32 111.5 2.5 1.9 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 EEQ73365.1 - 5e-16 58.0 0.9 1.3e-15 56.7 0.0 2.1 3 0 0 3 3 3 1 Rieske [2Fe-2S] domain Nucleoplasmin PF03066.10 EEQ73367.1 - 0.19 11.2 4.6 0.26 10.7 3.2 1.2 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EEQ73367.1 - 6.9 6.9 10.7 12 6.2 7.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF1275 PF06912.6 EEQ73369.1 - 9.7e-39 132.7 9.5 1.3e-38 132.2 6.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Gate PF07670.9 EEQ73369.1 - 0.036 13.9 1.2 0.082 12.8 0.9 1.5 1 0 0 1 1 1 0 Nucleoside recognition Chorismate_synt PF01264.16 EEQ73369.1 - 0.076 11.4 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Chorismate synthase CoA_transf_3 PF02515.12 EEQ73370.1 - 1.8e-60 203.4 0.3 3.4e-60 202.5 0.0 1.6 2 0 0 2 2 2 1 CoA-transferase family III Acyl-CoA_dh_1 PF00441.19 EEQ73371.1 - 1.8e-37 128.7 5.8 2.9e-37 128.0 4.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EEQ73371.1 - 2.6e-20 73.1 0.2 7e-20 71.7 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EEQ73371.1 - 5.7e-16 57.7 0.0 1.1e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EEQ73371.1 - 6.5e-15 55.5 4.5 1.2e-14 54.7 3.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Glucosaminidase PF01832.15 EEQ73371.1 - 0.0005 20.1 1.1 0.0044 17.1 0.1 2.3 2 0 0 2 2 2 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase MFS_1 PF07690.11 EEQ73372.1 - 9.6e-34 116.6 25.6 9.6e-34 116.6 17.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4534 PF15049.1 EEQ73372.1 - 0.3 10.6 2.7 0.33 10.5 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4534) ToxN_toxin PF13958.1 EEQ73374.1 - 0.052 13.2 0.2 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Toxin ToxN, type III toxin-antitoxin system dDENN PF03455.14 EEQ73374.1 - 0.089 12.8 0.2 0.3 11.2 0.0 1.9 2 0 0 2 2 2 0 dDENN domain adh_short PF00106.20 EEQ73375.1 - 3.6e-18 66.0 0.7 4.4e-18 65.7 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ73375.1 - 7.1e-11 42.3 0.0 8.7e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ73375.1 - 8.2e-09 35.3 0.1 1e-08 35.0 0.1 1.1 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EEQ73375.1 - 0.06 12.5 0.7 0.1 11.8 0.5 1.3 1 0 0 1 1 1 0 NmrA-like family DUF1416 PF07210.7 EEQ73375.1 - 0.13 11.8 0.3 0.44 10.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1416) DUF1776 PF08643.5 EEQ73375.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Hyd_WA PF06462.7 EEQ73376.1 - 0.15 11.6 0.6 15 5.3 0.0 2.4 2 0 0 2 2 2 0 Propeller ECH PF00378.15 EEQ73380.1 - 2.9e-44 151.0 0.0 3.6e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ERK-JNK_inhib PF15002.1 EEQ73382.1 - 0.33 10.2 2.2 0.21 10.9 0.2 1.6 2 0 0 2 2 2 0 ERK and JNK pathways, inhibitor zf-CCHC_2 PF13696.1 EEQ73383.1 - 0.00055 19.3 0.2 0.00096 18.5 0.1 1.4 1 0 0 1 1 1 1 Zinc knuckle Phage_Coat_Gp8 PF05371.7 EEQ73384.1 - 0.023 14.2 0.3 0.036 13.6 0.2 1.2 1 0 0 1 1 1 0 Phage major coat protein, Gp8 FoP_duplication PF13865.1 EEQ73386.1 - 9.1e-07 29.2 0.1 1.7e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.17 EEQ73386.1 - 6.6e-06 25.6 0.0 1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ73386.1 - 3.9e-05 23.4 0.0 6.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ73386.1 - 4.2e-05 23.4 0.0 6.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Snf7 PF03357.16 EEQ73391.1 - 6.2e-19 68.0 13.7 6.2e-19 68.0 9.5 1.7 1 1 1 2 2 2 1 Snf7 MerR-DNA-bind PF09278.6 EEQ73391.1 - 0.3 11.4 14.8 1.5 9.2 0.0 4.3 4 0 0 4 4 4 0 MerR, DNA binding DUF2730 PF10805.3 EEQ73391.1 - 0.61 9.8 5.6 3.7 7.3 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) CS PF04969.11 EEQ73392.1 - 2.7e-07 31.0 0.0 4.4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 CS domain DUF1446 PF07287.6 EEQ73393.1 - 4.6e-122 406.9 0.1 5.5e-122 406.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Mre11_DNA_bind PF04152.9 EEQ73394.1 - 2.6e-58 196.7 0.4 2.6e-58 196.7 0.3 2.0 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EEQ73394.1 - 6.4e-26 90.9 1.9 9.1e-26 90.4 1.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEQ73394.1 - 7.7e-05 22.5 0.0 0.00019 21.3 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EEQ73394.1 - 0.023 13.8 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily F-box PF00646.28 EEQ73395.1 - 4.3e-11 42.1 0.2 1.2e-10 40.7 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EEQ73395.1 - 6.5e-11 41.7 0.2 1.5e-10 40.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like Apc4_WD40 PF12894.2 EEQ73395.1 - 0.011 15.2 0.0 0.029 13.8 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Glyco_hydro_72 PF03198.9 EEQ73396.1 - 8.1e-123 409.3 0.1 9.9e-123 409.1 0.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EEQ73396.1 - 6.3e-05 22.3 0.0 0.0047 16.1 0.0 2.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EEQ73396.1 - 0.0038 16.1 0.0 0.0067 15.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain MAS20 PF02064.10 EEQ73397.1 - 1.7e-17 63.4 0.1 3.8e-17 62.3 0.1 1.5 1 1 0 1 1 1 1 MAS20 protein import receptor TetR_C_6 PF13977.1 EEQ73397.1 - 0.02 14.8 0.2 2.5 8.1 0.3 2.2 2 0 0 2 2 2 0 Bacterial transcriptional repressor Vps51 PF08700.6 EEQ73398.1 - 3.7e-17 61.9 1.9 3.7e-17 61.9 1.3 2.1 3 0 0 3 3 3 1 Vps51/Vps67 Sec5 PF15469.1 EEQ73398.1 - 0.0027 17.4 1.2 0.18 11.5 0.3 2.7 2 1 0 2 2 2 2 Exocyst complex component Sec5 ABC_tran PF00005.22 EEQ73399.1 - 3.6e-26 92.0 0.0 3.7e-12 46.7 0.0 3.4 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EEQ73399.1 - 3.4e-07 30.5 3.5 0.025 14.5 0.0 3.3 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EEQ73399.1 - 1.7e-05 24.6 0.1 0.041 13.7 0.0 2.6 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EEQ73399.1 - 0.032 14.3 0.5 0.86 9.7 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_13 PF13166.1 EEQ73399.1 - 0.072 11.5 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EEQ73399.1 - 0.13 11.8 0.1 0.13 11.8 0.1 2.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain Miro PF08477.8 EEQ73399.1 - 0.16 12.5 0.0 0.44 11.0 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 EEQ73399.1 - 0.63 10.3 1.5 1.4 9.1 1.1 1.6 1 0 0 1 1 1 0 AAA domain SGL PF08450.7 EEQ73400.1 - 1.2e-18 67.4 0.0 2.3e-18 66.4 0.0 1.3 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Angiomotin_C PF12240.3 EEQ73402.1 - 0.061 12.8 1.8 0.087 12.3 1.2 1.2 1 0 0 1 1 1 0 Angiomotin C terminal ATPgrasp_TupA PF14305.1 EEQ73402.1 - 0.094 12.0 0.1 0.13 11.5 0.1 1.1 1 0 0 1 1 1 0 TupA-like ATPgrasp DUF685 PF05085.7 EEQ73402.1 - 0.16 10.9 6.1 0.18 10.7 3.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF685) NPCC PF08058.6 EEQ73402.1 - 3.8 7.3 6.5 2.5 7.9 0.1 2.5 1 1 1 2 2 2 0 Nuclear pore complex component Terpene_synth PF01397.16 EEQ73403.1 - 0.0071 15.7 0.7 0.0081 15.5 0.5 1.1 1 0 0 1 1 1 1 Terpene synthase, N-terminal domain FPL PF09758.4 EEQ73403.1 - 0.0078 15.9 0.3 0.0097 15.6 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein C_GCAxxG_C_C PF09719.5 EEQ73403.1 - 0.34 10.7 2.0 0.42 10.4 1.3 1.3 1 1 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) Ndufs5 PF10200.4 EEQ73403.1 - 0.98 9.4 3.8 2.1 8.3 2.6 1.5 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CPSase_L_D2 PF02786.12 EEQ73404.1 - 1.3e-113 377.4 0.1 4.6e-84 280.9 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EEQ73404.1 - 1.2e-46 157.4 0.0 3.3e-46 156.0 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EEQ73404.1 - 5.5e-46 156.4 0.0 1.5e-45 155.0 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 EEQ73404.1 - 1.2e-42 144.9 0.0 2.2e-42 144.0 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 EEQ73404.1 - 1.5e-40 137.7 0.0 3.5e-40 136.5 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EEQ73404.1 - 5.8e-35 120.6 0.2 2.9e-20 72.7 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 EEQ73404.1 - 2.7e-33 115.0 0.0 6.8e-33 113.7 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain CPSase_L_chain PF00289.17 EEQ73404.1 - 1.2e-32 112.2 0.1 4.5e-17 62.1 0.0 3.7 3 0 0 3 3 3 3 Carbamoyl-phosphate synthase L chain, N-terminal domain MGS PF02142.17 EEQ73404.1 - 6.3e-23 80.5 0.0 8e-22 76.9 0.0 2.8 2 0 0 2 2 2 1 MGS-like domain ATPgrasp_Ter PF15632.1 EEQ73404.1 - 3e-21 75.5 0.1 2.8e-09 36.1 0.0 4.1 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EEQ73404.1 - 4.9e-17 61.9 0.2 2e-08 33.8 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EEQ73404.1 - 1.7e-15 56.7 0.1 1.3e-06 27.8 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EEQ73404.1 - 2.9e-06 26.9 0.1 0.00017 21.1 0.0 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 EEQ73404.1 - 2.6e-05 24.1 0.2 0.23 11.3 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.19 EEQ73404.1 - 0.0027 17.1 0.0 0.0064 15.9 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family Ion_trans PF00520.26 EEQ73405.1 - 8.3e-06 25.1 20.3 3.2e-05 23.2 14.1 2.0 1 1 0 1 1 1 1 Ion transport protein UPF0014 PF03649.8 EEQ73405.1 - 0.022 13.9 4.2 0.037 13.1 2.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0014) Synaptobrevin PF00957.16 EEQ73407.1 - 2.6e-31 107.0 0.0 3.5e-31 106.6 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EEQ73407.1 - 1.3e-24 85.5 0.0 2.1e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain SpoIIAA-like PF11964.3 EEQ73407.1 - 0.018 15.2 0.1 0.031 14.5 0.1 1.3 1 0 0 1 1 1 0 SpoIIAA-like DUF879 PF05947.7 EEQ73407.1 - 0.062 11.6 0.0 0.086 11.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF879) KOW PF00467.24 EEQ73408.1 - 6.9e-08 31.9 1.8 6.9e-08 31.9 1.2 2.5 2 0 0 2 2 2 1 KOW motif DUF1223 PF06764.6 EEQ73408.1 - 0.079 12.7 0.2 0.1 12.4 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1223) U79_P34 PF03064.11 EEQ73409.1 - 0.79 9.1 12.1 1.8 8.0 8.4 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Ost4 PF10215.4 EEQ73410.1 - 1.7e-19 69.0 0.5 2.2e-19 68.6 0.3 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase zf-CCCH PF00642.19 EEQ73411.1 - 4.8e-06 26.1 1.8 4.8e-06 26.1 1.2 2.7 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PTPS PF01242.14 EEQ73411.1 - 0.0027 17.3 0.8 0.16 11.6 0.1 2.4 2 0 0 2 2 2 2 6-pyruvoyl tetrahydropterin synthase Cwf_Cwc_15 PF04889.7 EEQ73411.1 - 0.0035 17.1 8.4 0.0035 17.1 5.8 2.6 2 1 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein DUF3797 PF12677.2 EEQ73412.1 - 0.026 14.1 0.5 0.062 12.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) Pyridox_oxidase PF01243.15 EEQ73413.1 - 0.0002 21.3 0.0 0.00038 20.4 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Aldedh PF00171.17 EEQ73414.1 - 1.4e-144 481.8 1.6 2.5e-123 411.8 0.3 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Metallophos PF00149.23 EEQ73415.1 - 5.4e-38 130.4 0.0 1.5e-32 112.6 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase DUF3573 PF12097.3 EEQ73416.1 - 0.044 12.3 2.9 0.045 12.3 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) L27_2 PF09045.5 EEQ73416.1 - 0.22 11.0 1.4 0.36 10.4 0.3 1.9 2 0 0 2 2 2 0 L27_2 v110 PF01639.12 EEQ73417.1 - 0.0037 16.8 4.1 0.0054 16.3 2.9 1.3 1 0 0 1 1 1 1 Viral family 110 C1_4 PF07975.7 EEQ73417.1 - 0.53 10.3 9.5 1.1 9.3 6.6 1.6 1 0 0 1 1 1 0 TFIIH C1-like domain DUF3815 PF12821.2 EEQ73417.1 - 5.2 7.0 9.1 2.9 7.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3815) Zn_clus PF00172.13 EEQ73419.1 - 1e-05 25.3 10.0 1.6e-05 24.6 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEQ73419.1 - 0.051 12.4 0.8 3.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Fungal specific transcription factor domain OCD_Mu_crystall PF02423.10 EEQ73420.1 - 6.6e-16 57.9 0.0 2.8e-15 55.9 0.0 1.9 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EEQ73420.1 - 1.8e-06 28.0 0.0 1.2e-05 25.3 0.0 2.2 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Ctr PF04145.10 EEQ73422.1 - 9.7e-42 142.4 0.5 1.2e-41 142.1 0.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family TraL PF07178.6 EEQ73422.1 - 0.035 14.1 2.3 1.5 8.8 0.1 2.1 2 0 0 2 2 2 0 TraL protein Smg4_UPF3 PF03467.10 EEQ73423.1 - 1.1e-21 77.6 0.0 4.2e-21 75.7 0.0 2.0 1 1 0 1 1 1 1 Smg-4/UPF3 family RRM_1 PF00076.17 EEQ73423.1 - 2.4e-08 33.4 0.1 2.2e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ73423.1 - 6.6e-06 26.0 0.0 6.3e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ73423.1 - 9.2e-05 22.2 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Wyosine_form PF08608.7 EEQ73424.1 - 3.5e-23 81.4 0.0 9.5e-23 80.0 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 EEQ73424.1 - 1.7e-11 44.3 0.0 7.1e-06 26.0 0.0 2.5 2 0 0 2 2 2 2 Flavodoxin AHSP PF09236.5 EEQ73425.1 - 0.033 14.3 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein tRNA-synt_1d PF00750.14 EEQ73427.1 - 5.6e-79 265.5 1.0 2.2e-78 263.5 0.7 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (R) Viral_DNA_bi PF02236.12 EEQ73428.1 - 0.021 15.0 0.3 0.041 14.0 0.2 1.6 1 0 0 1 1 1 0 Viral DNA-binding protein, all alpha domain DUF3508 PF12018.3 EEQ73428.1 - 0.051 12.5 5.7 0.053 12.4 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) DUF745 PF05335.8 EEQ73428.1 - 0.063 12.7 3.8 0.063 12.7 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF745) PBS_linker_poly PF00427.16 EEQ73428.1 - 0.082 12.5 1.3 0.12 12.0 0.5 1.6 1 1 1 2 2 2 0 Phycobilisome Linker polypeptide Ribosomal_L17 PF01196.14 EEQ73428.1 - 0.57 10.7 3.2 2.8 8.5 2.2 2.1 1 1 0 1 1 1 0 Ribosomal protein L17 DUF342 PF03961.8 EEQ73428.1 - 0.58 8.5 4.7 0.7 8.2 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Pro_dh PF01619.13 EEQ73430.1 - 2.9e-42 144.7 1.4 3.6e-42 144.4 1.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase AP_endonuc_2 PF01261.19 EEQ73430.1 - 6.1e-05 22.4 0.1 0.00026 20.3 0.0 2.0 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Aldedh PF00171.17 EEQ73431.1 - 6.1e-102 341.3 0.0 7.5e-102 341.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Histone PF00125.19 EEQ73432.1 - 9.2e-06 25.6 0.1 1.3e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF2781 PF10914.3 EEQ73434.1 - 2.4e-32 111.7 10.7 2.7e-32 111.6 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) EBP PF05241.7 EEQ73434.1 - 0.15 11.0 2.0 0.18 10.8 1.4 1.2 1 0 0 1 1 1 0 Emopamil binding protein MNSV_P7B PF06692.6 EEQ73434.1 - 0.15 11.8 0.5 0.38 10.5 0.4 1.8 1 1 0 1 1 1 0 Melon necrotic spot virus P7B protein zf-DHHC PF01529.15 EEQ73434.1 - 0.55 9.6 4.2 0.3 10.4 0.9 2.0 1 1 1 2 2 2 0 DHHC palmitoyltransferase AATase PF07247.7 EEQ73435.1 - 1.8e-24 86.1 0.0 2.4e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EEQ73435.1 - 0.017 14.0 0.4 0.1 11.4 0.0 2.3 2 1 1 3 3 3 0 Condensation domain Elf1 PF05129.8 EEQ73436.1 - 9e-30 102.2 0.5 1.2e-29 101.8 0.4 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-C2H2_6 PF13912.1 EEQ73436.1 - 0.14 12.1 0.5 0.14 12.1 0.3 2.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.10 EEQ73436.1 - 1.5 8.4 5.1 16 5.1 1.1 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger UPRTase PF14681.1 EEQ73437.1 - 1e-78 263.2 0.0 1.4e-78 262.8 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EEQ73437.1 - 0.0049 16.5 0.0 0.0084 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 EEQ73437.1 - 0.097 12.4 0.2 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) WAPL PF07814.8 EEQ73438.1 - 1.2e-33 116.3 0.3 1.6e-33 115.8 0.2 1.2 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Ras PF00071.17 EEQ73440.1 - 1.4e-44 151.3 0.2 1.6e-44 151.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ73440.1 - 2.1e-15 57.2 0.1 3e-15 56.7 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ73440.1 - 9.8e-09 34.6 0.0 1.2e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EEQ73440.1 - 2.3e-06 27.5 0.1 3.7e-06 26.8 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEQ73440.1 - 2.4e-06 27.0 0.1 4.5e-05 22.9 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EEQ73440.1 - 0.0033 16.6 0.0 0.0058 15.8 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit tRNA-synt_2b PF00587.20 EEQ73441.1 - 4.1e-32 111.1 0.1 7.9e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EEQ73441.1 - 6.4e-16 58.3 7.9 6.4e-16 58.3 5.5 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DNA_repr_REX1B PF14966.1 EEQ73441.1 - 0.41 11.0 3.6 3.2 8.1 0.9 2.6 2 0 0 2 2 2 0 DNA repair REX1-B Atg14 PF10186.4 EEQ73441.1 - 2.4 7.0 7.9 5.9 5.7 5.5 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IFT57 PF10498.4 EEQ73441.1 - 8.8 4.9 14.0 0.4 9.3 2.9 2.3 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 2-Hacid_dh_C PF02826.14 EEQ73442.1 - 4.7e-52 175.7 0.0 7.2e-52 175.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEQ73442.1 - 7.4e-35 119.3 0.0 1e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EEQ73442.1 - 5.1e-05 23.1 0.2 0.00012 21.9 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 EEQ73442.1 - 0.00021 20.6 0.2 0.00064 19.1 0.0 1.9 2 0 0 2 2 2 1 ACT domain AdoHcyase_NAD PF00670.16 EEQ73442.1 - 0.016 15.0 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 EEQ73442.1 - 0.03 13.6 0.1 0.087 12.1 0.0 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 EEQ73442.1 - 0.031 13.9 1.2 1.9 8.0 0.3 2.8 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.20 EEQ73443.1 - 5.4e-68 228.9 0.0 6.5e-68 228.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ73443.1 - 9.3e-32 110.1 0.0 1.2e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ73443.1 - 0.022 13.7 0.0 0.06 12.2 0.0 1.7 1 1 0 1 1 1 0 Kinase-like NADH_B2 PF14813.1 EEQ73444.1 - 0.036 13.7 0.1 0.038 13.6 0.0 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 P5-ATPase PF12409.3 EEQ73445.1 - 1.5e-39 134.5 0.0 2.9e-39 133.5 0.0 1.5 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 EEQ73445.1 - 2.1e-36 125.9 0.0 5.1e-36 124.6 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EEQ73445.1 - 1.7e-29 102.5 0.0 2.7e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EEQ73445.1 - 1.3e-16 61.6 0.0 8.4e-16 59.0 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ73445.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEQ73445.1 - 0.056 13.0 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase NAP PF00956.13 EEQ73446.1 - 3.9e-87 291.4 7.3 3.9e-87 291.4 5.0 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Myosin_head PF00063.16 EEQ73447.1 - 2.5e-246 819.0 0.3 2.5e-246 819.0 0.2 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 EEQ73447.1 - 2.9e-34 117.0 3.6 2.9e-34 117.0 2.5 2.3 2 0 0 2 2 1 1 DIL domain IQ PF00612.22 EEQ73447.1 - 1.3e-14 52.3 27.9 6.1e-05 22.3 0.5 6.9 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_10 PF12846.2 EEQ73447.1 - 0.0019 17.7 1.6 0.016 14.6 0.0 2.7 2 0 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 EEQ73447.1 - 0.0024 17.8 1.8 0.032 14.1 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain Reo_sigmaC PF04582.7 EEQ73447.1 - 0.0067 15.6 3.6 0.014 14.5 2.5 1.5 1 0 0 1 1 1 1 Reovirus sigma C capsid protein AAA_22 PF13401.1 EEQ73447.1 - 0.0079 16.3 0.1 0.0079 16.3 0.1 2.8 2 2 0 2 2 2 1 AAA domain GAS PF13851.1 EEQ73447.1 - 0.018 14.2 30.0 0.24 10.5 7.2 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding AAA_19 PF13245.1 EEQ73447.1 - 0.034 13.8 0.0 0.094 12.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain TMP_2 PF06791.8 EEQ73447.1 - 0.04 13.5 3.2 0.099 12.2 2.2 1.6 1 0 0 1 1 1 0 Prophage tail length tape measure protein Amidohydro_3 PF07969.6 EEQ73447.1 - 0.054 12.6 1.6 0.061 12.5 0.5 1.5 2 0 0 2 2 2 0 Amidohydrolase family Cortex-I_coil PF09304.5 EEQ73447.1 - 0.19 11.7 27.6 0.94 9.5 8.3 3.2 2 1 1 3 3 3 0 Cortexillin I, coiled coil IncA PF04156.9 EEQ73447.1 - 1.6 8.2 31.0 0.34 10.4 8.9 2.7 1 1 1 2 2 2 0 IncA protein FUSC PF04632.7 EEQ73447.1 - 4.3 5.6 7.0 6.8 4.9 4.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ham1p_like PF01725.11 EEQ73448.1 - 3.2e-35 121.2 0.0 7e-35 120.1 0.0 1.5 1 1 0 1 1 1 1 Ham1 family AAA_18 PF13238.1 EEQ73449.1 - 1e-24 87.2 0.1 2.3e-24 86.1 0.0 1.5 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EEQ73449.1 - 3e-14 53.8 0.7 6e-14 52.9 0.5 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EEQ73449.1 - 0.00032 20.6 0.0 0.00098 19.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EEQ73449.1 - 0.00044 20.1 0.0 0.03 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EEQ73449.1 - 0.00051 20.2 0.0 0.0013 18.9 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ADK PF00406.17 EEQ73449.1 - 0.0059 16.4 0.0 0.019 14.8 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase KTI12 PF08433.5 EEQ73449.1 - 0.0078 15.4 0.0 0.017 14.3 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 RNA_helicase PF00910.17 EEQ73449.1 - 0.009 16.1 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 EEQ73449.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.1 EEQ73449.1 - 0.017 15.0 0.1 0.1 12.4 0.0 1.9 1 1 0 2 2 2 0 Cytidylate kinase-like family NTPase_1 PF03266.10 EEQ73449.1 - 0.02 14.6 0.2 0.043 13.5 0.0 1.6 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.4 EEQ73449.1 - 0.021 13.8 0.0 0.028 13.4 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 EEQ73449.1 - 0.037 13.9 0.0 0.095 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EEQ73449.1 - 0.047 13.6 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 EEQ73449.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 EEQ73449.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Peptidase_C78 PF07910.8 EEQ73450.1 - 2.8e-61 206.4 0.0 3.9e-61 205.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 Hist_deacetyl PF00850.14 EEQ73450.1 - 0.067 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Histone deacetylase domain AA_kinase PF00696.23 EEQ73451.1 - 6.6e-39 133.8 0.3 1.1e-38 133.1 0.1 1.4 2 0 0 2 2 2 1 Amino acid kinase family ACT_7 PF13840.1 EEQ73451.1 - 1.2e-13 50.2 0.7 1.5e-11 43.6 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 EEQ73451.1 - 3.7e-12 45.4 0.2 6e-10 38.4 0.1 2.9 2 0 0 2 2 2 1 ACT domain SapB_1 PF05184.10 EEQ73451.1 - 0.044 13.6 0.2 0.12 12.2 0.2 1.7 1 0 0 1 1 1 0 Saposin-like type B, region 1 Fork_head PF00250.13 EEQ73452.1 - 2.6e-36 123.5 0.0 4.7e-36 122.7 0.0 1.4 1 0 0 1 1 1 1 Fork head domain Dicty_REP PF05086.7 EEQ73452.1 - 2.7 5.6 7.3 3.8 5.1 5.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein G10 PF01125.12 EEQ73453.1 - 1e-65 219.7 3.9 1.1e-65 219.5 2.7 1.0 1 0 0 1 1 1 1 G10 protein zf-Tim10_DDP PF02953.10 EEQ73454.1 - 2.1e-22 78.1 1.5 2.5e-22 77.9 1.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EEQ73454.1 - 0.014 14.8 1.3 0.018 14.4 0.9 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Ins_beta PF03488.9 EEQ73454.1 - 0.039 13.7 2.1 0.061 13.1 1.5 1.3 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type Ribosomal_L23eN PF03939.8 EEQ73455.1 - 9.2e-23 80.0 12.7 2.5e-22 78.6 8.8 1.8 1 1 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EEQ73455.1 - 6.1e-17 61.3 1.0 6.1e-17 61.3 0.7 1.7 2 0 0 2 2 2 1 Ribosomal protein L23 FimP PF09766.4 EEQ73456.1 - 0.08 11.9 0.0 0.088 11.8 0.0 1.0 1 0 0 1 1 1 0 Fms-interacting protein AAA PF00004.24 EEQ73457.1 - 2.8e-06 27.5 0.0 4.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.20 EEQ73458.1 - 3.1e-23 82.2 0.0 6.4e-23 81.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ73458.1 - 1.2e-10 40.9 0.6 1.4e-07 30.8 0.2 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEQ73458.1 - 4.2e-06 25.9 0.9 0.00091 18.2 0.0 2.6 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 EEQ73458.1 - 0.018 14.1 0.1 0.036 13.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ73458.1 - 0.035 13.8 0.1 0.051 13.3 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EEQ73458.1 - 0.042 13.1 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF3321 PF11968.3 EEQ73459.1 - 6.3e-95 316.9 0.0 7.9e-95 316.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Aa_trans PF01490.13 EEQ73460.1 - 5.6e-55 186.4 29.2 1.2e-45 155.7 6.8 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein YbjQ_1 PF01906.12 EEQ73461.1 - 2e-31 108.4 0.9 2.6e-31 108.1 0.6 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding SpoVAB PF13782.1 EEQ73461.1 - 0.081 12.9 0.2 0.11 12.4 0.2 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AB eRF1_2 PF03464.10 EEQ73462.1 - 4.8e-47 159.6 0.1 8.5e-47 158.8 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EEQ73462.1 - 2.4e-38 130.8 0.5 4.9e-38 129.8 0.4 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EEQ73462.1 - 3.2e-28 97.9 0.0 6e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 PDT PF00800.13 EEQ73463.1 - 4.4e-59 199.0 0.0 6.2e-59 198.5 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 EEQ73463.1 - 1.8e-05 24.1 0.1 0.00016 21.0 0.0 2.5 2 1 0 2 2 2 1 ACT domain MaoC_dehydratas PF01575.14 EEQ73464.1 - 0.00049 19.4 0.0 0.00089 18.6 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain DER1 PF04511.10 EEQ73465.1 - 4.3e-06 26.3 0.0 5e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 Der1-like family DKCLD PF08068.7 EEQ73466.1 - 4.5e-30 103.3 0.1 3.6e-29 100.4 0.0 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EEQ73466.1 - 2.7e-24 86.0 0.2 1.9e-21 76.7 0.1 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EEQ73466.1 - 6.2e-20 70.6 1.5 1.1e-19 69.8 1.1 1.4 1 0 0 1 1 1 1 PUA domain RNA_polI_A34 PF08208.6 EEQ73466.1 - 1.6 8.3 25.7 2.5 7.7 17.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RNase_H2-Ydr279 PF09468.5 EEQ73466.1 - 1.8 7.6 12.9 2.7 7.0 8.9 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) CLTH PF10607.4 EEQ73467.1 - 7.3e-36 123.0 0.1 1.5e-35 122.0 0.0 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EEQ73467.1 - 0.061 13.1 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 LisH TPR_4 PF07721.9 EEQ73467.1 - 1.2 9.7 3.5 55 4.6 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2431 PF10354.4 EEQ73468.1 - 3.9e-44 150.5 0.0 1.4e-28 99.9 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF2431) UAA PF08449.6 EEQ73469.1 - 4.4e-11 42.2 25.2 5.5e-11 41.9 17.5 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EEQ73469.1 - 1.6e-10 40.8 8.4 1.6e-10 40.8 5.8 2.8 1 1 2 3 3 3 1 Triose-phosphate Transporter family PHO4 PF01384.15 EEQ73469.1 - 0.00063 18.4 5.6 0.00063 18.4 3.9 2.4 1 1 1 2 2 2 1 Phosphate transporter family Metallophos_2 PF12850.2 EEQ73470.1 - 1.1e-06 28.6 0.4 3.3e-06 27.0 0.3 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EEQ73470.1 - 5e-05 22.7 1.7 0.00022 20.6 1.2 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase zf-C2H2 PF00096.21 EEQ73472.1 - 8.1e-10 38.4 44.0 0.094 13.1 1.3 8.1 8 1 1 9 9 9 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ73472.1 - 6.6e-09 35.4 34.3 0.032 14.5 0.3 7.5 7 1 1 8 8 8 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EEQ73472.1 - 4.3e-05 23.2 24.5 0.016 15.0 0.2 6.4 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEQ73472.1 - 0.002 18.2 26.7 0.65 10.2 0.1 6.2 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEQ73472.1 - 0.014 15.5 23.5 0.35 11.1 0.1 6.1 6 0 0 6 6 6 0 Zinc-finger of C2H2 type F-box PF00646.28 EEQ73473.1 - 0.0013 18.3 0.1 0.0043 16.6 0.1 1.9 1 0 0 1 1 1 1 F-box domain Herpes_UL36 PF03586.8 EEQ73473.1 - 0.011 14.8 0.1 0.021 13.9 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein TrmE_N PF10396.4 EEQ73474.1 - 4.9e-37 126.3 0.0 1.1e-36 125.2 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 EEQ73474.1 - 2.5e-24 85.4 0.1 8.1e-24 83.8 0.1 1.9 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 EEQ73474.1 - 2.8e-17 62.7 0.0 8.4e-17 61.1 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EEQ73474.1 - 1.3e-05 25.1 0.0 3e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GTP_EFTU PF00009.22 EEQ73474.1 - 1.5e-05 24.5 0.1 0.0061 16.0 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EEQ73474.1 - 7.4e-05 22.0 0.1 0.00044 19.5 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EEQ73474.1 - 0.00012 22.4 0.0 0.00058 20.3 0.0 2.2 1 1 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 EEQ73474.1 - 0.035 14.4 0.3 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 EEQ73474.1 - 0.058 13.3 0.8 10 6.0 0.0 3.2 2 2 2 4 4 4 0 AAA ATPase domain Glyco_hydro_3_C PF01915.17 EEQ73474.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain FH2 PF02181.18 EEQ73476.1 - 1.7e-80 270.6 0.5 1.7e-80 270.6 0.4 1.9 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 EEQ73476.1 - 1.9e-52 177.5 0.9 1.9e-52 177.5 0.6 3.1 2 1 1 3 3 3 2 Diaphanous FH3 Domain Drf_GBD PF06371.8 EEQ73476.1 - 6.3e-49 165.8 2.9 2.5e-47 160.6 0.0 3.0 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain PulG PF11773.3 EEQ73477.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin DUF2422 PF10337.4 EEQ73477.1 - 0.083 11.6 0.0 0.083 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DPM3 PF08285.6 EEQ73477.1 - 0.087 12.6 0.4 0.14 12.0 0.3 1.2 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) 2-Hacid_dh_C PF02826.14 EEQ73478.1 - 4e-30 104.2 0.0 1.1e-15 57.2 0.0 2.3 1 1 1 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEQ73478.1 - 3.7e-16 58.8 0.0 5e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain PALP PF00291.20 EEQ73479.1 - 1.5e-55 188.6 0.1 2e-55 188.2 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme tRNA-synt_1 PF00133.17 EEQ73481.1 - 1.2e-42 145.7 0.0 4.3e-12 44.8 0.1 5.6 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 EEQ73481.1 - 1.8e-39 134.9 0.0 2.8e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EEQ73481.1 - 1.5e-24 86.3 0.2 2.5e-16 59.3 0.0 4.2 3 1 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EEQ73481.1 - 5.6e-15 55.4 0.0 1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EEQ73481.1 - 0.0015 17.6 0.0 0.15 11.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 EEQ73481.1 - 0.0027 16.5 0.0 0.005 15.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) Suc_Fer-like PF06999.7 EEQ73483.1 - 3.9e-41 141.5 0.0 4.4e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Suc_Fer-like PF06999.7 EEQ73484.1 - 0.0044 17.0 0.0 0.0049 16.9 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Abi PF02517.11 EEQ73485.1 - 1e-14 54.3 14.9 1.4e-14 53.9 4.4 2.7 2 1 0 2 2 2 2 CAAX protease self-immunity VIT1 PF01988.14 EEQ73485.1 - 0.12 11.8 0.6 0.23 10.9 0.4 1.5 1 0 0 1 1 1 0 VIT family Pkinase PF00069.20 EEQ73486.1 - 0.00016 20.9 0.0 0.00026 20.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain FAD_binding_4 PF01565.18 EEQ73487.1 - 2.8e-21 75.4 0.6 5.9e-21 74.4 0.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEQ73487.1 - 0.0096 15.8 0.0 0.024 14.5 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF1275 PF06912.6 EEQ73488.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) KIAA1328 PF15369.1 EEQ73489.1 - 0.14 11.9 2.8 0.26 11.0 2.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 MBOAT PF03062.14 EEQ73490.1 - 4.7e-47 160.6 5.1 7.6e-47 159.9 3.5 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF3375 PF11855.3 EEQ73490.1 - 0.24 10.1 0.2 0.34 9.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) Gti1_Pac2 PF09729.4 EEQ73495.1 - 4.1e-63 212.2 0.0 9.9e-63 210.9 0.0 1.6 2 0 0 2 2 2 1 Gti1/Pac2 family ABC2_membrane PF01061.19 EEQ73498.1 - 1.9e-84 282.0 59.1 3.2e-47 160.4 12.0 2.7 4 0 0 4 4 2 2 ABC-2 type transporter ABC_tran PF00005.22 EEQ73498.1 - 1.6e-37 128.8 0.0 5.4e-19 68.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EEQ73498.1 - 1.8e-30 104.5 2.5 3e-26 91.0 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter cobW PF02492.14 EEQ73498.1 - 1.4e-07 31.0 0.0 0.00024 20.5 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain ABC_trans_N PF14510.1 EEQ73498.1 - 1.6e-07 31.3 0.1 3.7e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_21 PF13304.1 EEQ73498.1 - 7.8e-07 29.3 0.2 0.001 19.1 0.2 3.1 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EEQ73498.1 - 1.7e-06 27.6 0.1 0.021 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EEQ73498.1 - 2.4e-06 27.8 0.0 0.00099 19.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain UPF0079 PF02367.12 EEQ73498.1 - 8e-06 25.4 0.6 0.035 13.7 0.1 2.5 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 EEQ73498.1 - 1e-05 25.6 0.0 0.012 15.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 EEQ73498.1 - 1.1e-05 25.4 0.2 0.00037 20.5 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EEQ73498.1 - 1.1e-05 24.9 0.0 0.022 14.2 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF258 PF03193.11 EEQ73498.1 - 1.6e-05 24.1 0.0 0.00053 19.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EEQ73498.1 - 4.7e-05 24.1 0.0 0.0056 17.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EEQ73498.1 - 7.7e-05 22.7 0.2 0.0019 18.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EEQ73498.1 - 0.00011 22.0 0.0 0.013 15.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 EEQ73498.1 - 0.00011 21.3 12.2 0.00011 21.3 8.4 3.8 3 1 1 4 4 3 1 ABC-2 family transporter protein NACHT PF05729.7 EEQ73498.1 - 0.00066 19.3 0.8 0.1 12.2 0.1 2.8 3 0 0 3 3 2 1 NACHT domain AAA_29 PF13555.1 EEQ73498.1 - 0.0017 17.8 4.4 0.039 13.4 0.2 2.9 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_19 PF13245.1 EEQ73498.1 - 0.0018 17.9 0.7 2.4 7.9 0.1 2.6 2 0 0 2 2 2 2 Part of AAA domain SMC_N PF02463.14 EEQ73498.1 - 0.0028 16.9 0.1 0.11 11.6 0.0 2.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EEQ73498.1 - 0.0029 17.5 0.0 0.23 11.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.24 EEQ73498.1 - 0.0037 17.4 0.0 4 7.6 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EEQ73498.1 - 0.0071 15.2 0.1 0.23 10.3 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_15 PF13175.1 EEQ73498.1 - 0.0071 15.4 0.0 2.8 6.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 EEQ73498.1 - 0.012 14.5 0.5 1.2 7.9 0.1 2.6 2 0 0 2 2 2 0 NB-ARC domain Arch_ATPase PF01637.13 EEQ73498.1 - 0.012 15.3 0.0 2.7 7.6 0.0 2.7 2 0 0 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 EEQ73498.1 - 0.028 13.9 0.1 1.5 8.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EEQ73498.1 - 0.031 14.7 0.0 0.98 9.9 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein PduV-EutP PF10662.4 EEQ73498.1 - 0.032 13.7 0.4 0.41 10.1 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 EEQ73498.1 - 0.033 13.6 1.6 0.88 8.9 0.2 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_30 PF13604.1 EEQ73498.1 - 0.04 13.4 0.7 3.2 7.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 EEQ73498.1 - 0.097 11.6 0.5 0.4 9.6 0.1 2.0 2 0 0 2 2 2 0 Septin Serendipity_A PF05482.7 EEQ73498.1 - 0.23 9.8 0.4 0.35 9.2 0.3 1.2 1 0 0 1 1 1 0 Serendipity locus alpha protein (SRY-A) FeoB_N PF02421.13 EEQ73498.1 - 0.94 8.7 2.2 1.5 8.0 0.0 2.3 3 0 0 3 3 3 0 Ferrous iron transport protein B Tyr-DNA_phospho PF06087.7 EEQ73501.1 - 2.4e-83 280.2 0.0 3e-83 279.9 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EEQ73501.1 - 6.3e-05 22.7 0.0 0.0028 17.3 0.0 2.5 2 0 0 2 2 2 1 PLD-like domain NAD_binding_8 PF13450.1 EEQ73502.1 - 3.2e-12 46.3 0.4 5.7e-11 42.2 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEQ73502.1 - 3.3e-10 39.4 0.0 2.2e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EEQ73502.1 - 2.1e-06 28.0 0.3 0.0049 17.2 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEQ73502.1 - 5.4e-06 26.4 0.0 0.00019 21.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEQ73502.1 - 8.9e-06 24.7 0.4 8.9e-06 24.7 0.3 1.4 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EEQ73502.1 - 1.3e-05 23.9 0.3 0.0003 19.3 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EEQ73502.1 - 3.6e-05 23.9 0.1 0.00015 21.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEQ73502.1 - 9.7e-05 21.5 0.0 0.0002 20.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.19 EEQ73502.1 - 0.00014 21.0 0.0 0.065 12.3 0.0 2.9 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EEQ73502.1 - 0.00041 20.1 0.1 0.0016 18.2 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Peptidase_S9 PF00326.16 EEQ73502.1 - 0.0017 17.5 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Trp_halogenase PF04820.9 EEQ73502.1 - 0.0026 16.4 0.5 0.02 13.5 0.1 2.0 2 0 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.2 EEQ73502.1 - 0.0031 16.6 0.0 0.0082 15.2 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EEQ73502.1 - 0.0033 16.4 0.2 0.0049 15.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EEQ73502.1 - 0.0049 15.9 0.1 0.0086 15.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.15 EEQ73502.1 - 0.022 14.8 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.16 EEQ73502.1 - 0.023 14.2 0.1 0.17 11.4 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 EEQ73502.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Malic_M PF03949.10 EEQ73502.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain GIDA PF01134.17 EEQ73502.1 - 0.54 9.0 1.6 0.47 9.2 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A adh_short PF00106.20 EEQ73503.1 - 1.7e-21 76.8 0.0 2.3e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ73503.1 - 3.4e-14 52.9 0.0 5.2e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEQ73503.1 - 5.5e-07 29.2 0.0 1e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EEQ73503.1 - 0.00015 20.8 0.0 0.00024 20.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EEQ73503.1 - 0.00047 18.9 0.0 0.00064 18.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EEQ73503.1 - 0.0013 17.6 0.0 0.0019 17.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EEQ73503.1 - 0.0028 16.9 0.0 0.005 16.1 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEQ73503.1 - 0.047 13.6 0.1 0.07 13.1 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding Sec1 PF00995.18 EEQ73504.1 - 5.8e-153 510.5 0.0 6.6e-153 510.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Glyco_tran_WecB PF03808.8 EEQ73504.1 - 0.0023 17.3 0.0 0.35 10.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase WecB/TagA/CpsF family tRNA-synt_1c PF00749.16 EEQ73505.1 - 2.2e-95 318.9 0.0 2.7e-95 318.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EEQ73505.1 - 2e-29 102.4 0.0 4e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain CDP-OH_P_transf PF01066.16 EEQ73506.1 - 8e-18 64.6 5.1 1.5e-17 63.7 3.5 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase GIDA PF01134.17 EEQ73507.1 - 8.4e-155 515.4 0.0 1e-154 515.1 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EEQ73507.1 - 5.6e-16 58.3 0.1 1.8e-15 56.7 0.0 1.9 2 0 0 2 2 2 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 EEQ73507.1 - 4.8e-07 29.8 0.6 1.6e-06 28.1 0.4 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEQ73507.1 - 3e-06 26.5 0.6 4.6e-06 25.9 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EEQ73507.1 - 0.00013 21.6 0.1 0.00027 20.5 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 EEQ73507.1 - 0.00016 20.7 2.9 0.079 11.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEQ73507.1 - 0.00077 18.4 3.5 0.0011 17.8 1.1 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EEQ73507.1 - 0.0065 16.5 0.0 0.022 14.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEQ73507.1 - 0.027 12.9 0.7 0.32 9.3 0.3 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 EEQ73507.1 - 0.033 14.6 0.5 0.094 13.1 0.3 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DJ-1_PfpI PF01965.19 EEQ73507.1 - 0.05 13.0 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family Trp_halogenase PF04820.9 EEQ73507.1 - 0.45 9.0 1.7 12 4.3 1.1 2.1 1 1 1 2 2 2 0 Tryptophan halogenase ARD PF03079.9 EEQ73508.1 - 8.9e-46 155.6 0.0 1.1e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EEQ73508.1 - 9.4e-10 37.8 0.1 1.4e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EEQ73508.1 - 9.1e-05 22.1 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EEQ73508.1 - 0.00054 19.4 0.0 0.00078 18.8 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EEQ73508.1 - 0.033 13.5 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF2404 PF10296.4 EEQ73509.1 - 0.00011 22.2 0.0 0.00019 21.4 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DUF1183 PF06682.7 EEQ73510.1 - 2.2e-60 204.9 0.0 3.2e-60 204.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Phage_Gp23 PF10669.4 EEQ73511.1 - 0.0019 18.2 0.5 0.0047 17.0 0.4 1.6 1 0 0 1 1 1 1 Protein gp23 (Bacteriophage A118) BRE1 PF08647.6 EEQ73512.1 - 4.4e-27 93.8 14.0 4.4e-27 93.8 9.7 7.0 5 1 2 8 8 8 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 EEQ73512.1 - 1.4e-09 37.8 10.7 2.4e-09 37.0 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ73512.1 - 6.1e-09 35.4 8.4 1.1e-08 34.6 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ73512.1 - 8e-08 31.8 10.8 1.5e-07 30.9 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ73512.1 - 2.3e-07 30.5 8.3 4.5e-07 29.5 5.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EEQ73512.1 - 2.9e-06 26.8 11.4 5.1e-06 26.1 7.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EEQ73512.1 - 1.3e-05 24.7 6.5 3.5e-05 23.4 4.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Reo_sigmaC PF04582.7 EEQ73512.1 - 0.00044 19.5 43.0 0.005 16.0 3.9 5.2 1 1 5 6 6 6 4 Reovirus sigma C capsid protein zf-C3HC4_4 PF15227.1 EEQ73512.1 - 0.0018 18.0 7.2 0.0034 17.2 5.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EEQ73512.1 - 0.0021 18.1 3.3 0.0076 16.3 1.9 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger DUF4201 PF13870.1 EEQ73512.1 - 0.0022 17.4 7.2 0.0022 17.4 5.0 6.8 3 1 4 7 7 7 2 Domain of unknown function (DUF4201) ATG16 PF08614.6 EEQ73512.1 - 0.0073 16.1 76.7 0.94 9.2 2.7 6.1 1 1 2 4 4 4 2 Autophagy protein 16 (ATG16) DUF745 PF05335.8 EEQ73512.1 - 0.0098 15.4 5.5 0.0098 15.4 3.8 5.5 5 1 1 6 6 5 1 Protein of unknown function (DUF745) CENP-F_leu_zip PF10473.4 EEQ73512.1 - 0.012 15.5 8.5 0.012 15.5 5.9 6.2 3 1 3 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-RING_4 PF14570.1 EEQ73512.1 - 0.035 13.6 7.7 0.13 11.8 5.4 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EEQ73512.1 - 0.035 13.6 3.0 0.072 12.6 2.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF1272 PF06906.6 EEQ73512.1 - 0.039 13.7 5.6 0.093 12.6 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_6 PF14835.1 EEQ73512.1 - 0.13 12.0 4.0 0.26 11.1 2.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FYVE PF01363.16 EEQ73512.1 - 1.1 9.2 12.3 19 5.2 8.5 2.5 1 1 1 2 2 2 0 FYVE zinc finger zf-Nse PF11789.3 EEQ73512.1 - 2.1 7.9 10.2 0.38 10.3 4.3 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C2H2 PF00096.21 EEQ73512.1 - 2.3 8.7 7.4 3.3 8.2 0.2 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-FCS PF06467.9 EEQ73512.1 - 4.5 6.9 8.9 6 6.5 0.1 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif TPR_MLP1_2 PF07926.7 EEQ73512.1 - 5.1 6.8 77.5 2.1 8.1 1.6 6.7 3 1 4 7 7 7 0 TPR/MLP1/MLP2-like protein UreF PF01730.11 EEQ73513.1 - 4.5e-14 52.7 0.5 1.5e-13 51.0 0.4 1.8 1 1 0 1 1 1 1 UreF ABC1 PF03109.11 EEQ73514.1 - 1.5e-32 112.0 0.0 2.9e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Cwf_Cwc_15 PF04889.7 EEQ73515.1 - 0.0044 16.7 15.8 0.006 16.3 10.9 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein AMPKBI PF04739.10 EEQ73516.1 - 6.6e-25 86.8 0.4 2.3e-24 85.1 0.2 2.1 1 1 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain NIF PF03031.13 EEQ73519.1 - 1.3e-22 80.1 0.1 3.1e-21 75.7 0.1 2.2 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase GSK-3_bind PF05350.7 EEQ73519.1 - 0.0026 17.2 0.2 0.0062 16.0 0.1 1.6 1 0 0 1 1 1 1 Glycogen synthase kinase-3 binding DUF947 PF06102.7 EEQ73520.1 - 5.9e-41 140.0 19.6 1.1e-40 139.1 13.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF947) Gon7 PF08738.5 EEQ73520.1 - 0.043 13.8 0.2 0.043 13.8 0.1 3.6 2 1 1 3 3 3 0 Gon7 family Menin PF05053.8 EEQ73520.1 - 1.9 6.5 9.5 3.4 5.7 6.6 1.4 1 0 0 1 1 1 0 Menin EF1G PF00647.14 EEQ73521.1 - 1.8e-46 156.2 0.0 3.5e-46 155.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EEQ73521.1 - 2.4e-11 43.4 0.0 9.3e-11 41.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEQ73521.1 - 6e-08 32.4 0.0 1.4e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EEQ73521.1 - 1.7e-07 31.3 0.0 3.5e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EEQ73521.1 - 2.1e-07 31.0 0.0 4.6e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EEQ73521.1 - 1.3e-06 28.8 0.1 2.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EEQ73521.1 - 0.048 13.6 0.1 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Ribosomal_S9 PF00380.14 EEQ73522.1 - 3.7e-35 120.8 0.0 7e-35 119.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF1947 PF09183.5 EEQ73523.1 - 0.11 12.2 0.1 0.15 11.7 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1947) Methyltransf_23 PF13489.1 EEQ73526.1 - 2.4e-21 76.1 0.0 5.9e-21 74.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ73526.1 - 3e-10 39.8 0.0 5.9e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ73526.1 - 4.9e-10 39.9 0.0 1.5e-09 38.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ73526.1 - 1.7e-09 38.0 0.0 5.9e-09 36.3 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ73526.1 - 2.7e-09 37.4 0.0 6.6e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ73526.1 - 6.3e-08 32.9 0.0 6.7e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EEQ73526.1 - 0.0057 16.0 0.0 0.0086 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EEQ73526.1 - 0.0073 15.3 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EEQ73526.1 - 0.014 15.4 0.0 0.04 13.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.14 EEQ73526.1 - 0.022 14.7 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EEQ73526.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase EF-hand_1 PF00036.27 EEQ73528.1 - 3.7e-27 91.5 12.9 4.2e-08 31.9 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EEQ73528.1 - 1.4e-22 79.5 2.9 5.1e-12 45.7 0.4 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EEQ73528.1 - 5.9e-21 72.4 5.4 4.8e-05 22.9 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EEQ73528.1 - 5.1e-19 66.6 13.0 2.5e-07 29.7 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EEQ73528.1 - 6.9e-15 54.4 14.8 1.4e-05 24.6 0.7 4.5 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EEQ73528.1 - 6.1e-07 29.4 0.0 0.00094 19.1 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EEQ73528.1 - 6.6e-05 22.6 7.9 0.054 13.2 0.2 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EEQ73528.1 - 0.017 14.9 0.0 0.57 10.1 0.0 2.8 2 1 1 3 3 3 0 EF-hand domain Anthrax-tox_M PF09156.5 EEQ73528.1 - 0.038 13.1 1.1 0.21 10.6 0.0 2.0 2 0 0 2 2 2 0 Anthrax toxin lethal factor, middle domain EPL1 PF10513.4 EEQ73529.1 - 4.3e-31 108.3 6.2 4.2e-30 105.1 0.6 2.6 2 1 0 2 2 2 2 Enhancer of polycomb-like SET PF00856.23 EEQ73530.1 - 2.1e-13 50.8 0.0 6.8e-13 49.2 0.0 1.8 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 EEQ73530.1 - 1.3e-10 41.2 0.1 5.1e-10 39.3 0.0 2.0 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding Peptidase_M22 PF00814.20 EEQ73531.1 - 9.3e-85 284.3 0.0 1.1e-84 284.1 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Hydantoinase_A PF01968.13 EEQ73531.1 - 0.073 12.1 0.0 0.16 11.0 0.0 1.5 1 1 0 1 1 1 0 Hydantoinase/oxoprolinase RNase_H PF00075.19 EEQ73532.1 - 6.1e-08 33.0 0.0 1e-07 32.3 0.0 1.3 1 0 0 1 1 1 1 RNase H Glyco_hydro_38C PF07748.8 EEQ73532.1 - 0.013 14.3 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain RNA_pol_L_2 PF13656.1 EEQ73533.1 - 1.3e-30 104.6 0.0 2e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EEQ73533.1 - 4.8e-11 41.6 0.0 8.1e-11 40.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RabGAP-TBC PF00566.13 EEQ73533.1 - 0.0022 17.5 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SoxY PF13501.1 EEQ73533.1 - 0.098 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Sulfur oxidation protein SoxY Complex1_LYR_2 PF13233.1 EEQ73534.1 - 9.8e-07 29.2 0.3 1.3e-06 28.8 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EEQ73534.1 - 6.3e-06 25.8 0.2 1.2e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EEQ73534.1 - 6.4e-05 23.0 0.3 9.6e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 Complex1_LYR-like R-HINP1I PF11463.3 EEQ73534.1 - 0.18 11.2 1.0 0.94 8.8 0.1 1.9 1 1 1 2 2 2 0 R.HinP1I restriction endonuclease phage_tail_N PF08400.5 EEQ73535.1 - 0.11 12.1 0.4 0.18 11.5 0.3 1.3 1 0 0 1 1 1 0 Prophage tail fibre N-terminal DUF4207 PF13904.1 EEQ73535.1 - 8.1 5.7 27.1 1.1 8.5 10.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) Abhydrolase_6 PF12697.2 EEQ73536.1 - 7.5e-14 52.1 0.1 1.2e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ73536.1 - 2.9e-13 49.9 0.0 4.7e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold TRAPPC9-Trs120 PF08626.6 EEQ73537.1 - 2.4e-148 495.5 0.0 4.4e-148 494.6 0.0 1.4 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF3684 PF12449.3 EEQ73538.1 - 0 1535.6 0.0 0 1535.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 EEQ73538.1 - 3.2e-05 23.5 0.0 8.7e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EEQ73538.1 - 0.017 14.8 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pro-rich PF15240.1 EEQ73538.1 - 0.37 10.8 16.6 0.68 10.0 11.5 1.3 1 0 0 1 1 1 0 Proline-rich WLM PF08325.5 EEQ73538.1 - 0.68 9.7 4.9 1.8 8.3 0.1 2.5 2 0 0 2 2 2 0 WLM domain Chorismate_bind PF00425.13 EEQ73539.1 - 2.4e-66 223.7 0.0 5.5e-66 222.5 0.0 1.7 2 0 0 2 2 2 1 chorismate binding enzyme GATase PF00117.23 EEQ73539.1 - 1.8e-27 96.0 0.0 2.8e-26 92.1 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EEQ73539.1 - 2.2e-13 50.4 0.0 4.8e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EEQ73539.1 - 0.00015 21.3 0.4 0.0019 17.6 0.3 2.3 1 1 0 1 1 1 1 Peptidase C26 RdRP PF05183.7 EEQ73540.1 - 9e-163 543.0 0.0 1.5e-162 542.3 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase Med6 PF04934.9 EEQ73541.1 - 1.1e-41 141.6 0.0 1.5e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Lysine_decarbox PF03641.9 EEQ73542.1 - 3.8e-27 94.7 0.0 7.9e-27 93.6 0.0 1.6 1 1 0 1 1 1 1 Possible lysine decarboxylase Proteasome PF00227.21 EEQ73543.1 - 2e-49 167.4 0.0 2.4e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEQ73543.1 - 8.4e-12 44.1 0.3 1.3e-11 43.5 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Flg_hook PF02120.11 EEQ73543.1 - 0.056 13.1 0.7 8.2 6.1 0.0 3.1 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK Vps55 PF04133.9 EEQ73544.1 - 1.5e-44 150.5 6.3 1.7e-44 150.4 4.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 UPF0220 PF05255.6 EEQ73546.1 - 5.3e-67 224.2 2.9 5.9e-67 224.0 2.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Fes1 PF08609.5 EEQ73547.1 - 8.7e-32 109.4 5.3 1.8e-31 108.4 3.0 1.9 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 EEQ73547.1 - 0.0001 22.5 0.9 0.00038 20.6 0.0 2.2 2 1 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.1 EEQ73547.1 - 0.00079 19.8 0.2 0.005 17.2 0.0 2.4 2 0 0 2 2 2 1 HEAT-like repeat HEAT PF02985.17 EEQ73547.1 - 0.089 12.9 0.1 0.56 10.4 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat Actin PF00022.14 EEQ73548.1 - 3.1e-160 532.9 0.0 3.5e-160 532.7 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EEQ73548.1 - 0.036 14.4 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) GARS_A PF01071.14 EEQ73549.1 - 4.2e-83 277.6 0.1 8e-83 276.7 0.0 1.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EEQ73549.1 - 6.7e-36 122.7 0.0 5.8e-35 119.7 0.0 2.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EEQ73549.1 - 1.3e-31 109.6 0.0 3.3e-31 108.3 0.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EEQ73549.1 - 1.7e-25 89.0 0.2 1.7e-25 89.0 0.1 2.2 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EEQ73549.1 - 5.7e-16 58.5 5.9 1.4e-15 57.2 1.4 3.3 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EEQ73549.1 - 2e-09 37.4 0.0 7.4e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EEQ73549.1 - 1e-07 31.0 0.0 2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EEQ73549.1 - 8.7e-06 25.1 0.0 1.9e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EEQ73549.1 - 0.00018 21.4 0.0 0.0005 19.9 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EEQ73549.1 - 0.00048 19.4 0.1 0.00088 18.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 EEQ73549.1 - 0.038 13.3 0.0 0.086 12.2 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Pet127 PF08634.5 EEQ73550.1 - 9.5e-118 392.2 0.1 1.3e-117 391.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 PH PF00169.24 EEQ73551.1 - 0.0082 16.3 0.0 0.023 14.8 0.0 1.8 1 0 0 1 1 1 1 PH domain LRR_6 PF13516.1 EEQ73551.1 - 0.012 15.5 8.2 92 3.5 0.0 7.9 8 0 0 8 8 8 0 Leucine Rich repeat Gly_transf_sug PF04488.10 EEQ73552.1 - 7.4e-20 71.2 0.0 1.5e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EEQ73552.1 - 0.24 9.8 1.1 1.1 7.6 0.1 1.9 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Peptidase_M24 PF00557.19 EEQ73553.1 - 1.3e-39 135.9 0.0 1.5e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EEQ73553.1 - 0.00012 21.9 3.2 0.00031 20.5 2.2 1.7 1 0 0 1 1 1 1 MYND finger Peptidase_M24 PF00557.19 EEQ73554.1 - 6.9e-38 130.2 0.2 9.8e-38 129.8 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DnaJ PF00226.26 EEQ73555.1 - 1.6e-21 75.7 0.1 2.8e-21 74.9 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Bul1_N PF04425.7 EEQ73557.1 - 2.1e-05 23.3 8.4 0.00086 17.9 4.3 3.0 2 1 0 2 2 2 1 Bul1 N terminus Arrestin_N PF00339.24 EEQ73557.1 - 3.5e-05 23.6 0.0 0.00043 20.1 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 EEQ73557.1 - 0.00017 20.8 0.0 0.00034 19.9 0.0 1.4 1 0 0 1 1 1 1 Bul1 C terminus YEATS PF03366.11 EEQ73558.1 - 5.2e-21 74.1 0.5 8.9e-21 73.4 0.4 1.4 1 0 0 1 1 1 1 YEATS family Ran_BP1 PF00638.13 EEQ73560.1 - 2.2e-50 169.8 1.6 3.8e-50 169.0 1.1 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EEQ73560.1 - 7.8e-05 22.3 0.4 0.00054 19.6 0.3 2.0 1 1 0 1 1 1 1 WH1 domain TBCC PF07986.7 EEQ73561.1 - 0.16 11.3 0.0 0.47 9.8 0.0 1.7 2 0 0 2 2 2 0 Tubulin binding cofactor C Glyco_transf_15 PF01793.11 EEQ73562.1 - 1.1e-133 445.2 3.2 1.4e-133 444.9 2.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PH PF00169.24 EEQ73564.1 - 1.8e-28 98.7 0.7 7.8e-14 51.7 0.0 2.2 2 0 0 2 2 2 2 PH domain PH_9 PF15410.1 EEQ73564.1 - 3.6e-12 46.5 1.1 9.9e-06 25.7 0.0 3.8 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.1 EEQ73564.1 - 8.7e-11 42.0 2.7 0.00026 21.1 0.3 3.2 2 2 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.1 EEQ73564.1 - 0.00097 19.1 0.1 0.12 12.4 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain Mcp5_PH PF12814.2 EEQ73564.1 - 0.011 15.6 0.2 0.61 10.0 0.0 2.2 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology DOT1 PF08123.8 EEQ73565.1 - 1.8e-75 252.7 0.0 2.5e-75 252.2 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 EEQ73565.1 - 0.003 17.5 0.3 0.0088 16.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ73565.1 - 0.026 14.1 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Kdo PF06293.9 EEQ73566.1 - 0.00085 18.4 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EEQ73566.1 - 0.012 14.8 0.1 0.014 14.5 0.1 1.2 1 0 0 1 1 1 0 Protein kinase domain Myosin_N PF02736.14 EEQ73566.1 - 0.07 12.8 0.3 0.16 11.6 0.2 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Ras PF00071.17 EEQ73568.1 - 8.9e-56 187.7 0.1 1e-55 187.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ73568.1 - 8.3e-20 71.4 0.0 1.5e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ73568.1 - 2.6e-12 46.3 0.0 2.9e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEQ73568.1 - 1.2e-07 31.1 0.0 1.5e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEQ73568.1 - 3.9e-07 30.0 0.0 5.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEQ73568.1 - 4e-07 29.6 0.0 1.8e-05 24.2 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EEQ73568.1 - 0.00044 20.4 0.0 0.00071 19.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 EEQ73568.1 - 0.00086 18.9 0.2 0.048 13.1 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein DUF258 PF03193.11 EEQ73568.1 - 0.0015 17.7 0.9 0.0031 16.7 0.1 1.8 2 1 0 2 2 2 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EEQ73568.1 - 0.0038 16.9 0.8 0.0087 15.7 0.1 1.7 2 0 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 EEQ73568.1 - 0.0038 17.2 0.1 0.038 13.9 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain Septin PF00735.13 EEQ73568.1 - 0.0076 15.2 0.1 0.025 13.5 0.0 1.8 2 0 0 2 2 2 1 Septin PduV-EutP PF10662.4 EEQ73568.1 - 0.0083 15.6 0.1 0.15 11.5 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EEQ73568.1 - 0.011 14.9 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 EEQ73568.1 - 0.012 15.3 0.0 0.033 13.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EEQ73568.1 - 0.012 15.1 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EEQ73568.1 - 0.014 15.0 0.1 0.035 13.8 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EEQ73568.1 - 0.019 14.4 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain cobW PF02492.14 EEQ73568.1 - 0.024 14.0 0.0 0.099 12.0 0.0 1.8 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EEQ73568.1 - 0.075 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain EamA PF00892.15 EEQ73569.1 - 9.5e-07 28.8 34.9 1.2e-05 25.3 4.0 3.1 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 EEQ73569.1 - 1.3e-05 24.2 10.8 1.3e-05 24.2 7.5 1.6 2 0 0 2 2 2 1 UAA transporter family DUF914 PF06027.7 EEQ73569.1 - 8.6e-05 21.5 11.6 8.6e-05 21.5 8.0 1.9 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 EEQ73569.1 - 0.0066 16.6 5.1 0.0066 16.6 3.5 3.6 3 2 1 4 4 4 2 Multidrug resistance efflux transporter Gly_kinase PF02595.10 EEQ73571.1 - 1.7e-114 382.5 4.1 1.9e-114 382.2 2.8 1.0 1 0 0 1 1 1 1 Glycerate kinase family MFS_1 PF07690.11 EEQ73572.1 - 5.3e-35 120.7 24.2 5.3e-35 120.7 16.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ73572.1 - 1.3e-10 40.4 6.1 1.3e-10 40.4 4.2 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Spb1_C PF07780.7 EEQ73573.1 - 1.3e-72 243.7 32.0 1.3e-72 243.7 22.2 3.6 3 1 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 EEQ73573.1 - 1.3e-56 190.5 8.6 1.3e-56 190.5 6.0 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 EEQ73573.1 - 1.8e-54 184.5 0.0 3.6e-54 183.4 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase YgaB PF14182.1 EEQ73573.1 - 0.034 14.3 5.0 0.24 11.6 3.5 2.5 1 0 0 1 1 1 0 YgaB-like protein UPF0254 PF06787.6 EEQ73573.1 - 0.075 12.5 0.9 2.8 7.4 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0254) Fungal_trans PF04082.13 EEQ73575.1 - 0.00052 18.9 0.0 0.00086 18.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain EF-hand_4 PF12763.2 EEQ73576.1 - 0.014 15.1 0.1 0.038 13.7 0.0 1.7 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DNA_ligase_A_M PF01068.16 EEQ73577.1 - 3.3e-47 160.4 0.0 1e-46 158.9 0.0 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EEQ73577.1 - 5e-38 130.6 0.0 8.5e-38 129.9 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EEQ73577.1 - 1.1e-16 61.0 0.0 4.8e-16 58.9 0.0 2.2 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EEQ73577.1 - 1.9e-09 37.5 0.1 1.6e-07 31.3 0.0 3.0 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.14 EEQ73577.1 - 0.00099 18.8 0.0 0.038 13.6 0.0 3.0 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain PTCB-BRCT PF12738.2 EEQ73577.1 - 0.15 11.9 0.1 7.2 6.5 0.1 2.5 2 0 0 2 2 2 0 twin BRCT domain DUF2667 PF10868.3 EEQ73578.1 - 0.11 12.8 0.1 0.16 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2667) CN_hydrolase PF00795.17 EEQ73580.1 - 5.1e-16 58.5 0.2 4.6e-14 52.1 0.1 2.9 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Fungal_trans PF04082.13 EEQ73582.1 - 8e-34 116.6 0.9 2.9e-33 114.8 0.6 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Metallophos PF00149.23 EEQ73583.1 - 1.4e-34 119.2 0.8 3e-29 101.8 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase DUF4646 PF15496.1 EEQ73586.1 - 5.2e-09 36.1 0.0 8.8e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) ALG3 PF05208.8 EEQ73587.1 - 1.6e-131 438.9 24.5 1.8e-131 438.7 17.0 1.0 1 0 0 1 1 1 1 ALG3 protein FtsH_ext PF06480.10 EEQ73587.1 - 0.0026 17.9 1.6 0.057 13.5 0.2 3.0 2 1 0 2 2 2 1 FtsH Extracellular Glycos_trans_3N PF02885.12 EEQ73587.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain eIF-1a PF01176.14 EEQ73588.1 - 2.1e-17 62.2 0.0 3e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Pkinase PF00069.20 EEQ73589.1 - 1e-61 208.3 0.0 1.6e-61 207.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ73589.1 - 3e-36 124.8 0.0 4.9e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EEQ73589.1 - 5.3e-32 109.3 12.9 2.3e-17 62.4 2.7 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 EEQ73589.1 - 1.2e-21 76.1 29.0 6.1e-12 45.0 6.8 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EEQ73589.1 - 3.3e-13 49.9 4.0 9.9e-13 48.4 2.8 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EEQ73589.1 - 0.069 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FYVE_2 PF02318.11 EEQ73589.1 - 0.26 11.2 15.9 0.42 10.5 2.7 2.6 2 0 0 2 2 2 0 FYVE-type zinc finger Uds1 PF15456.1 EEQ73589.1 - 6 6.8 6.1 0.69 9.9 0.5 2.1 2 0 0 2 2 2 0 Up-regulated During Septation PHD_2 PF13831.1 EEQ73589.1 - 7.5 5.9 16.1 11 5.4 3.5 2.6 2 0 0 2 2 2 0 PHD-finger TFCD_C PF12612.3 EEQ73591.1 - 2.5e-42 144.4 0.0 7.2e-42 143.0 0.0 1.9 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 EEQ73591.1 - 2.7e-06 26.9 12.7 1.3 9.2 0.0 7.5 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.1 EEQ73591.1 - 2.7e-05 24.3 5.2 0.28 11.4 0.3 5.2 4 2 1 5 5 5 2 HEAT repeats Aldo_ket_red PF00248.16 EEQ73591.1 - 0.019 13.7 0.0 0.094 11.5 0.0 2.0 2 0 0 2 2 2 0 Aldo/keto reductase family Vac14_Fab1_bd PF12755.2 EEQ73591.1 - 0.044 14.1 0.0 14 6.1 0.0 3.1 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region IFRD PF05004.8 EEQ73591.1 - 0.089 11.8 0.2 0.38 9.7 0.0 2.1 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) RRM_1 PF00076.17 EEQ73592.1 - 1.6e-23 82.1 3.4 8.2e-12 44.5 0.1 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ73592.1 - 5.6e-17 61.3 0.0 8.3e-10 38.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ73592.1 - 5.3e-16 58.3 1.1 7.4e-07 29.0 0.0 2.9 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ATP-synt_D PF01813.12 EEQ73593.1 - 5.7e-65 218.5 2.0 7.7e-65 218.1 1.4 1.2 1 0 0 1 1 1 1 ATP synthase subunit D Viral_P18 PF04521.8 EEQ73593.1 - 0.5 9.8 3.9 9.8 5.6 0.1 2.4 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Prefoldin PF02996.12 EEQ73593.1 - 0.95 9.1 5.1 0.77 9.4 0.1 3.0 3 1 1 4 4 4 0 Prefoldin subunit TPR_14 PF13428.1 EEQ73594.1 - 1.2e-14 53.4 6.0 2.8 8.8 0.0 11.5 11 1 1 12 12 11 3 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ73594.1 - 2.4e-10 40.2 0.1 0.26 11.2 0.0 7.2 6 1 0 6 6 6 1 Tetratricopeptide repeat Suf PF05843.9 EEQ73594.1 - 1.6e-09 37.8 13.3 0.085 12.5 0.0 6.0 4 1 1 6 6 6 4 Suppressor of forked protein (Suf) TPR_11 PF13414.1 EEQ73594.1 - 1.1e-07 31.3 3.2 2.9 7.6 0.0 7.2 7 1 0 7 7 7 1 TPR repeat TPR_19 PF14559.1 EEQ73594.1 - 4.3e-07 30.1 0.0 0.13 12.6 0.0 6.2 6 1 0 7 7 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ73594.1 - 6.4e-06 25.7 8.1 22 5.2 0.0 7.6 7 0 0 7 7 7 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EEQ73594.1 - 1.6e-05 24.6 8.8 1 9.1 0.1 6.7 6 1 0 7 7 7 1 Mad3/BUB1 homology region 1 HAT PF02184.11 EEQ73594.1 - 0.00011 21.8 0.9 2.4 7.9 0.0 5.7 4 0 0 4 4 4 1 HAT (Half-A-TPR) repeat TPR_8 PF13181.1 EEQ73594.1 - 0.00045 19.8 5.6 1 9.3 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ73594.1 - 0.0014 18.2 5.4 18 5.4 0.0 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat NRDE-2 PF08424.5 EEQ73594.1 - 0.007 15.2 12.7 0.056 12.3 1.1 5.7 3 2 1 4 4 4 1 NRDE-2, necessary for RNA interference TPR_17 PF13431.1 EEQ73594.1 - 0.59 10.4 0.0 0.59 10.4 0.0 6.2 10 0 0 10 10 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ73594.1 - 6.9 7.3 13.7 25 5.6 0.0 7.5 9 0 0 9 9 8 0 Tetratricopeptide repeat WD40 PF00400.27 EEQ73595.1 - 4.3e-52 172.2 22.1 9.6e-11 41.1 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EEQ73595.1 - 9.9e-05 22.1 0.0 0.074 12.7 0.0 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF1795 PF08786.6 EEQ73598.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1795) DUF677 PF05055.7 EEQ73600.1 - 0.21 10.2 0.6 0.22 10.1 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DEC-1_N PF04625.8 EEQ73600.1 - 1.8 7.1 6.7 2 7.0 4.7 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Histone PF00125.19 EEQ73601.1 - 0.057 13.5 0.2 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 OspD PF03207.8 EEQ73602.1 - 0.11 11.6 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Borrelia outer surface protein D (OspD) Tox-ODYAM1 PF15642.1 EEQ73604.1 - 0.86 8.2 2.8 2.2 6.8 2.0 1.5 2 0 0 2 2 2 0 Toxin in Odyssella and Amoebophilus GET2 PF08690.5 EEQ73604.1 - 5.2 6.2 10.9 23 4.0 7.5 2.1 1 0 0 1 1 1 0 GET complex subunit GET2 TruB_N PF01509.13 EEQ73605.1 - 1.1e-43 148.8 0.0 3.6e-43 147.2 0.0 1.7 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) DUF605 PF04652.11 EEQ73605.1 - 0.049 13.0 20.2 0.065 12.6 14.0 1.1 1 0 0 1 1 1 0 Vta1 like Med3 PF11593.3 EEQ73605.1 - 2.6 7.1 16.6 3.6 6.7 11.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DNMT1-RFD PF12047.3 EEQ73606.1 - 0.021 14.5 0.0 0.084 12.5 0.0 2.0 2 0 0 2 2 2 0 Cytosine specific DNA methyltransferase replication foci domain Ebp2 PF05890.7 EEQ73607.1 - 4.5e-91 304.9 5.7 4.5e-91 304.9 4.0 2.0 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 MFS_1 PF07690.11 EEQ73609.1 - 3e-27 95.2 30.4 3e-27 95.2 21.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily HSBP1 PF06825.7 EEQ73610.1 - 1.1e-17 63.2 0.3 1.5e-17 62.8 0.2 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 EEQ73610.1 - 0.0002 20.6 1.5 0.22 10.9 0.0 2.3 2 0 0 2 2 2 2 Trimeric coiled-coil oligomerisation domain of matrilin NPV_P10 PF05531.7 EEQ73610.1 - 0.0089 16.2 1.1 0.012 15.8 0.6 1.4 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 EEQ73610.1 - 0.011 15.5 0.6 0.013 15.3 0.4 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Corona_S2 PF01601.11 EEQ73610.1 - 0.018 13.2 0.4 0.02 13.0 0.3 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein CAP_N PF01213.14 EEQ73610.1 - 0.025 13.8 0.1 0.028 13.6 0.0 1.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal KfrA_N PF11740.3 EEQ73610.1 - 0.029 14.8 0.7 0.029 14.8 0.5 1.1 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term AKNA PF12443.3 EEQ73610.1 - 0.031 14.2 0.6 0.047 13.7 0.4 1.6 1 1 0 1 1 1 0 AT-hook-containing transcription factor UPF0184 PF03670.8 EEQ73610.1 - 0.033 14.3 3.0 0.21 11.7 2.1 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) DELLA PF12041.3 EEQ73610.1 - 0.033 13.8 0.3 0.28 10.8 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal PMC2NT PF08066.7 EEQ73610.1 - 0.039 14.2 1.3 0.057 13.7 0.6 1.4 1 1 0 1 1 1 0 PMC2NT (NUC016) domain LXG PF04740.7 EEQ73610.1 - 0.046 13.5 0.6 0.053 13.2 0.4 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily DUF330 PF03886.8 EEQ73610.1 - 0.049 13.0 0.2 0.082 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF330) Prp19 PF08606.6 EEQ73610.1 - 0.069 12.8 0.1 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Prp19/Pso4-like Exonuc_VII_L PF02601.10 EEQ73610.1 - 0.071 12.2 0.8 0.07 12.3 0.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF935 PF06074.7 EEQ73610.1 - 0.081 11.6 1.8 0.088 11.5 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Syntaxin PF00804.20 EEQ73610.1 - 0.1 12.7 1.7 0.12 12.5 1.2 1.2 1 0 0 1 1 1 0 Syntaxin DUF16 PF01519.11 EEQ73610.1 - 0.13 12.5 0.6 0.15 12.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 SPX PF03105.14 EEQ73610.1 - 0.13 11.9 2.1 0.14 11.9 1.4 1.0 1 0 0 1 1 1 0 SPX domain WXG100 PF06013.7 EEQ73610.1 - 0.16 11.9 1.7 0.42 10.6 1.2 1.7 1 1 0 1 1 1 0 Proteins of 100 residues with WXG AATF-Che1 PF13339.1 EEQ73610.1 - 0.26 11.4 2.3 0.82 9.8 1.6 1.7 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor V-SNARE PF05008.10 EEQ73610.1 - 0.37 10.9 2.8 1.8 8.8 1.9 2.2 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Thioredoxin PF00085.15 EEQ73611.1 - 4.6e-60 199.7 0.0 5.5e-29 99.9 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EEQ73611.1 - 8.2e-20 71.2 0.7 2e-19 70.0 0.2 1.9 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EEQ73611.1 - 6.4e-16 58.5 0.0 1.4e-06 28.4 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EEQ73611.1 - 5.9e-13 48.6 0.0 1.9e-05 24.5 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EEQ73611.1 - 7.5e-12 45.2 0.0 0.00028 20.9 0.0 3.6 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 EEQ73611.1 - 3.6e-07 29.9 0.0 0.012 15.2 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.1 EEQ73611.1 - 1.2e-05 24.8 0.0 0.015 14.8 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Redoxin PF08534.5 EEQ73611.1 - 3.5e-05 23.3 0.0 0.31 10.5 0.0 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_3 PF13192.1 EEQ73611.1 - 0.00027 20.6 0.0 0.37 10.6 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin domain TraF PF13728.1 EEQ73611.1 - 0.00075 19.0 0.0 0.028 13.9 0.0 2.3 2 0 0 2 2 2 1 F plasmid transfer operon protein Glutaredoxin PF00462.19 EEQ73611.1 - 0.01 15.8 0.1 7.7 6.5 0.0 2.9 2 1 0 2 2 2 0 Glutaredoxin DDE_Tnp_1_2 PF13586.1 EEQ73611.1 - 0.028 14.5 0.0 5.1 7.3 0.0 2.5 2 0 0 2 2 2 0 Transposase DDE domain Thioredoxin_4 PF13462.1 EEQ73611.1 - 0.3 11.0 5.5 29 4.6 0.0 4.1 3 2 2 5 5 5 0 Thioredoxin MKT1_C PF12246.3 EEQ73612.1 - 9.4e-77 257.2 0.0 1.9e-76 256.2 0.0 1.5 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EEQ73612.1 - 8.3e-33 112.5 0.0 1.9e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 EEQ73612.1 - 3e-14 52.8 0.0 5.8e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EEQ73612.1 - 6.6e-05 23.1 0.0 0.00015 21.9 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain DIOX_N PF14226.1 EEQ73613.1 - 6.1e-18 65.4 0.1 1e-17 64.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EEQ73613.1 - 2.4e-11 43.7 0.0 2.9e-10 40.3 0.0 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-MYND PF01753.13 EEQ73614.1 - 1.8e-07 30.8 19.8 4.2e-07 29.7 13.7 1.6 1 0 0 1 1 1 1 MYND finger GTP_CH_N PF12471.3 EEQ73617.1 - 1.2e-93 312.1 0.0 1.8e-93 311.5 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EEQ73617.1 - 4.6e-17 61.7 0.0 7.3e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II FlaC_arch PF05377.6 EEQ73617.1 - 0.024 14.4 0.2 0.14 12.0 0.1 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Ribosomal_S3Ae PF01015.13 EEQ73618.1 - 4.4e-77 257.8 5.7 5.2e-77 257.5 3.9 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydrolase_6 PF12697.2 EEQ73619.1 - 7.9e-24 84.7 0.0 1e-23 84.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ73619.1 - 1.7e-22 80.1 0.0 2e-22 79.9 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ73619.1 - 2.1e-07 30.7 0.0 4.6e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EEQ73619.1 - 0.0045 16.4 0.0 0.0065 15.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Chlorophyllase PF07224.6 EEQ73619.1 - 0.016 14.0 0.1 0.064 12.0 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase Thioesterase PF00975.15 EEQ73619.1 - 0.019 15.1 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain LCAT PF02450.10 EEQ73619.1 - 0.025 13.5 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.20 EEQ73619.1 - 0.027 14.0 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Ndr PF03096.9 EEQ73619.1 - 0.058 11.8 0.0 0.12 10.8 0.0 1.4 2 0 0 2 2 2 0 Ndr family Chlorophyllase2 PF12740.2 EEQ73619.1 - 0.073 11.9 0.0 0.67 8.7 0.0 2.0 2 0 0 2 2 2 0 Chlorophyllase enzyme Ribonuclease_3 PF00636.21 EEQ73620.1 - 9.3e-15 55.0 0.0 5.1e-14 52.7 0.0 2.2 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EEQ73620.1 - 2.9e-12 46.6 0.0 5.1e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like DUF4589 PF15252.1 EEQ73620.1 - 0.029 14.2 1.1 0.046 13.5 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) MRP-S33 PF08293.6 EEQ73621.1 - 8.7e-29 99.3 0.0 1.1e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 DUF382 PF04037.8 EEQ73622.1 - 8.1e-62 206.7 2.4 2.4e-61 205.2 0.9 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 EEQ73622.1 - 2.3e-21 74.8 6.3 6e-21 73.5 4.4 1.8 1 0 0 1 1 1 1 PSP LIME1 PF15332.1 EEQ73622.1 - 0.016 14.4 0.7 3.3 6.8 0.0 2.6 2 0 0 2 2 2 0 Lck-interacting transmembrane adapter 1 CAF-1_p150 PF11600.3 EEQ73625.1 - 0.0032 16.8 0.9 0.0057 16.0 0.6 1.3 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal ER_lumen_recept PF00810.13 EEQ73626.1 - 5.5e-38 130.7 0.3 8.8e-38 130.0 0.2 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor XRCC4 PF06632.7 EEQ73629.1 - 3.5e-08 32.6 3.6 3.5e-08 32.6 2.5 2.0 1 1 1 2 2 2 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3585 PF12130.3 EEQ73629.1 - 0.00011 22.1 1.3 0.00011 22.1 0.9 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3585) Cytomega_UL20A PF05984.7 EEQ73629.1 - 0.078 13.1 11.4 0.053 13.7 6.1 2.1 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein DASH_Dad3 PF08656.5 EEQ73629.1 - 0.092 12.4 2.3 0.23 11.1 1.6 1.7 1 0 0 1 1 1 0 DASH complex subunit Dad3 IncA PF04156.9 EEQ73629.1 - 0.55 9.8 7.9 0.07 12.7 1.7 2.0 2 0 0 2 2 2 0 IncA protein V_ATPase_I PF01496.14 EEQ73629.1 - 0.71 7.6 5.0 1.3 6.7 3.6 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.3 EEQ73629.1 - 7.4 6.4 18.4 2.1 8.2 7.5 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.7 EEQ73629.1 - 7.8 6.9 7.4 13 6.2 0.5 3.2 2 1 1 3 3 3 0 SlyX Molybdopterin PF00384.17 EEQ73630.1 - 4.5e-71 239.8 0.0 1.2e-68 231.8 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 EEQ73630.1 - 5.1e-19 67.2 0.1 1.3e-18 65.9 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 EEQ73630.1 - 1.2e-15 57.3 0.1 2.8e-15 56.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2_4 PF13510.1 EEQ73630.1 - 0.0025 17.6 0.1 0.0095 15.7 0.0 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.22 EEQ73630.1 - 0.12 12.0 1.1 3 7.5 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.6 EEQ73630.1 - 0.36 10.6 2.1 5.7 6.8 1.5 2.5 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4_6 PF12837.2 EEQ73630.1 - 0.43 10.5 3.2 0.45 10.4 0.9 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain TPT PF03151.11 EEQ73631.1 - 1.8e-36 125.0 3.8 1.8e-36 125.0 2.6 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EEQ73631.1 - 2.9e-07 30.5 29.2 0.00031 20.7 7.1 3.0 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EEQ73631.1 - 4.7e-06 25.7 18.5 2.8e-05 23.1 12.8 2.0 1 1 0 1 1 1 1 UAA transporter family Peptidase_S9 PF00326.16 EEQ73632.1 - 1e-09 37.9 0.4 2e-09 36.9 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EEQ73632.1 - 0.014 14.8 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PUF PF00806.14 EEQ73633.1 - 1.8e-31 105.8 2.0 8.4e-06 24.9 0.0 7.9 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat Ssl1 PF04056.9 EEQ73635.1 - 5.3e-71 238.2 0.0 1.5e-70 236.7 0.0 1.7 1 1 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 EEQ73635.1 - 1.2e-08 35.2 0.0 2.2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Ribosomal_60s PF00428.14 EEQ73635.1 - 0.17 12.3 4.1 0.37 11.2 2.5 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Peptidase_M1 PF01433.15 EEQ73636.1 - 2.9e-120 401.9 0.0 6.9e-120 400.7 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 EEQ73636.1 - 2.9e-76 256.7 0.0 5e-76 256.0 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EEQ73636.1 - 2.7e-22 79.1 0.5 5.4e-22 78.1 0.3 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Dicty_REP PF05086.7 EEQ73636.1 - 0.051 11.3 4.4 0.08 10.6 3.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 EEQ73636.1 - 3.3 7.4 28.0 6.7 6.4 19.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Ras PF00071.17 EEQ73637.1 - 1.2e-65 219.8 0.4 1.4e-65 219.6 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ73637.1 - 1.4e-21 77.2 0.0 2.2e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ73637.1 - 1.5e-16 60.1 0.1 1.8e-16 59.9 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEQ73637.1 - 1.9e-05 23.9 0.0 2.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EEQ73637.1 - 6.2e-05 22.5 0.1 0.00013 21.5 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEQ73637.1 - 8.5e-05 22.4 0.0 0.00013 21.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 EEQ73637.1 - 0.00034 20.8 0.1 0.17 12.0 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 EEQ73637.1 - 0.0008 18.6 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EEQ73637.1 - 0.0017 18.5 0.0 0.0032 17.6 0.0 1.6 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.13 EEQ73637.1 - 0.0043 16.3 0.0 0.029 13.6 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EEQ73637.1 - 0.014 14.6 0.0 0.032 13.4 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EEQ73637.1 - 0.025 14.5 0.1 0.11 12.5 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain Septin PF00735.13 EEQ73637.1 - 0.035 13.1 0.1 0.22 10.4 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_29 PF13555.1 EEQ73637.1 - 0.044 13.3 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EEQ73637.1 - 0.06 13.2 0.1 0.17 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EEQ73637.1 - 0.069 12.8 0.0 0.13 12.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 EEQ73637.1 - 0.072 13.3 0.0 0.17 12.1 0.0 1.7 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EEQ73637.1 - 0.11 11.9 0.1 0.62 9.5 0.0 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Mito_carr PF00153.22 EEQ73638.1 - 5.2e-54 179.9 0.1 1.4e-17 63.1 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 EEQ73638.1 - 0.00054 19.7 0.2 0.0013 18.4 0.1 1.7 1 0 0 1 1 1 1 UcrQ family ATP_synt_I PF03899.10 EEQ73638.1 - 0.2 11.8 8.0 1.3 9.2 0.1 3.6 2 1 1 3 3 3 0 ATP synthase I chain Pkinase PF00069.20 EEQ73644.1 - 1.7e-05 24.1 0.0 2.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EEQ73644.1 - 4.7e-05 22.5 0.1 6.7e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AceK PF06315.6 EEQ73644.1 - 0.00013 20.3 0.1 0.00017 20.0 0.1 1.2 1 0 0 1 1 1 1 Isocitrate dehydrogenase kinase/phosphatase (AceK) APH PF01636.18 EEQ73644.1 - 0.0002 21.2 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ73644.1 - 0.0036 16.8 0.1 0.0077 15.8 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 EEQ73644.1 - 0.0042 16.1 0.1 0.0058 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EEQ73644.1 - 0.012 14.9 0.9 0.018 14.3 0.6 1.2 1 0 0 1 1 1 0 RIO1 family zf-C2H2_4 PF13894.1 EEQ73645.1 - 0.036 14.4 0.9 0.036 14.4 0.7 3.2 2 1 0 2 2 2 0 C2H2-type zinc finger GAS PF13851.1 EEQ73645.1 - 0.041 13.0 0.8 0.049 12.8 0.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4201 PF13870.1 EEQ73645.1 - 0.078 12.4 5.2 0.2 11.1 3.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Thioredoxin_9 PF14595.1 EEQ73645.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin IL7 PF01415.11 EEQ73646.1 - 0.042 13.4 3.4 0.16 11.5 2.4 2.0 1 1 0 1 1 1 0 Interleukin 7/9 family tRNA-synt_2 PF00152.15 EEQ73652.1 - 0.09 11.5 2.1 0.35 9.6 0.5 1.8 1 1 1 2 2 2 0 tRNA synthetases class II (D, K and N) TPR_20 PF14561.1 EEQ73652.1 - 0.099 12.7 0.6 0.18 11.9 0.4 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Catalase PF00199.14 EEQ73653.1 - 2.4e-35 121.9 0.8 1.3e-18 66.9 0.0 3.1 1 1 2 3 3 3 3 Catalase Catalase-rel PF06628.7 EEQ73653.1 - 1.6e-06 27.8 0.0 4.4e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Catalase-related immune-responsive Transketolase_N PF00456.16 EEQ73654.1 - 1.9e-149 497.0 0.0 2.7e-149 496.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EEQ73654.1 - 7.3e-45 152.6 0.0 1.2e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EEQ73654.1 - 7.1e-13 48.5 0.0 1.9e-12 47.2 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EEQ73654.1 - 2.8e-07 29.7 0.0 0.00036 19.5 0.0 2.3 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EEQ73654.1 - 0.0021 16.8 0.3 0.0034 16.1 0.2 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Mur_ligase_C PF02875.16 EEQ73654.1 - 0.12 12.4 0.0 0.42 10.6 0.0 1.9 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Spermine_synth PF01564.12 EEQ73655.1 - 4.9e-94 313.8 0.1 6e-94 313.5 0.0 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 EEQ73655.1 - 0.0006 20.3 0.0 0.001 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ73655.1 - 0.0008 19.0 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ73655.1 - 0.0032 17.9 0.2 0.014 15.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.11 EEQ73655.1 - 0.013 14.4 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 MTS PF05175.9 EEQ73655.1 - 0.034 13.5 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_24 PF13578.1 EEQ73655.1 - 0.053 14.3 0.1 0.14 13.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ73655.1 - 0.073 13.5 0.1 0.2 12.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.13 EEQ73655.1 - 0.082 12.0 0.5 0.83 8.7 0.2 2.3 1 1 2 3 3 3 0 O-methyltransferase bZIP_1 PF00170.16 EEQ73657.1 - 6.5e-08 32.4 10.5 1.5e-07 31.2 6.1 2.0 1 1 1 2 2 2 2 bZIP transcription factor COG5 PF10392.4 EEQ73657.1 - 4.5e-05 23.4 3.9 7.2e-05 22.7 2.7 1.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 TMF_TATA_bd PF12325.3 EEQ73657.1 - 6.1e-05 22.7 2.0 9.5e-05 22.1 1.4 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding bZIP_2 PF07716.10 EEQ73657.1 - 0.0049 16.6 7.0 0.0049 16.6 4.8 2.4 2 1 1 3 3 2 1 Basic region leucine zipper IncA PF04156.9 EEQ73657.1 - 0.014 14.9 5.7 0.02 14.5 3.9 1.1 1 0 0 1 1 1 0 IncA protein NPV_P10 PF05531.7 EEQ73657.1 - 0.021 15.0 0.7 0.039 14.1 0.5 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Noelin-1 PF12308.3 EEQ73657.1 - 0.048 13.4 5.3 1.3 8.8 0.2 2.2 1 1 1 2 2 2 0 Neurogenesis glycoprotein V_ATPase_I PF01496.14 EEQ73657.1 - 0.067 11.0 1.3 0.078 10.8 0.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 EEQ73657.1 - 0.14 11.6 2.9 0.16 11.4 1.1 1.7 1 1 1 2 2 2 0 Septum formation initiator FlxA PF14282.1 EEQ73657.1 - 0.35 10.8 5.2 0.92 9.4 2.9 2.0 1 1 0 1 1 1 0 FlxA-like protein APG6 PF04111.7 EEQ73657.1 - 0.48 9.4 7.0 0.7 8.8 4.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_Maf PF03131.12 EEQ73657.1 - 1.2 9.4 14.3 2.4 8.5 9.7 1.6 1 1 1 2 2 2 0 bZIP Maf transcription factor DUF972 PF06156.8 EEQ73657.1 - 3.3 8.0 6.7 1.1 9.6 2.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4140 PF13600.1 EEQ73657.1 - 4.2 7.8 5.8 31 5.0 4.0 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) G-alpha PF00503.15 EEQ73661.1 - 2.2e-113 378.9 0.0 2.5e-113 378.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EEQ73661.1 - 4.6e-14 52.0 1.0 1.9e-09 37.0 0.0 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEQ73661.1 - 1.2e-06 27.8 0.0 0.0036 16.4 0.0 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EEQ73661.1 - 0.0035 17.8 0.0 0.25 11.8 0.0 2.8 2 1 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 EEQ73661.1 - 0.028 13.9 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EEQ73661.1 - 0.03 14.2 0.0 5.3 7.0 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEQ73661.1 - 0.08 12.3 0.0 6.2 6.2 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF2231 PF09990.4 EEQ73661.1 - 0.13 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) DUF1713 PF08213.6 EEQ73662.1 - 3.3e-12 45.7 22.7 5.8e-12 44.9 15.7 1.4 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.5 EEQ73662.1 - 0.0027 17.6 0.1 0.0087 16.0 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial protein Pet20 VCX_VCY PF15231.1 EEQ73662.1 - 0.34 11.3 15.3 0.15 12.4 5.6 2.5 2 0 0 2 2 2 0 Variable charge X/Y family ATP-synt_C PF00137.16 EEQ73663.1 - 1.1e-31 108.4 28.0 2.6e-17 62.4 9.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ABA_GPCR PF12430.3 EEQ73663.1 - 0.1 11.7 1.1 2.1 7.4 0.1 2.1 2 0 0 2 2 2 0 Abscisic acid G-protein coupled receptor Flavi_NS4A PF01350.12 EEQ73663.1 - 1 8.9 4.9 1.3 8.6 1.4 2.0 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A GerA PF03323.8 EEQ73663.1 - 5.3 5.0 6.0 3.6 5.6 0.8 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein Pmp3 PF01679.12 EEQ73666.1 - 3.7e-26 90.5 5.3 4.1e-26 90.4 3.7 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM_helix PF05552.7 EEQ73666.1 - 0.45 10.2 3.7 0.63 9.7 0.9 2.0 2 0 0 2 2 2 0 Conserved TM helix CFEM PF05730.6 EEQ73668.1 - 0.0075 16.0 2.4 0.014 15.1 1.7 1.4 1 0 0 1 1 1 1 CFEM domain DUF533 PF04391.7 EEQ73668.1 - 0.41 10.0 5.2 0.048 13.0 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Hydrolase_6 PF13344.1 EEQ73670.1 - 1.9e-22 79.0 0.0 3.9e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ73670.1 - 1.1e-10 41.0 0.0 7.2e-10 38.4 0.0 2.4 2 1 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EEQ73670.1 - 0.018 15.2 0.0 4.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF676 PF05057.9 EEQ73671.1 - 1.2e-48 165.3 0.0 1.8e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EEQ73671.1 - 1.2e-06 28.3 0.0 1.8e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EEQ73671.1 - 9.2e-06 25.3 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 EEQ73671.1 - 0.00014 21.5 0.0 0.00025 20.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EEQ73671.1 - 0.0011 18.8 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 EEQ73671.1 - 0.0074 15.3 0.0 0.06 12.4 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) RNase_T PF00929.19 EEQ73672.1 - 1.2e-08 35.3 0.0 7.1e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 Exonuclease Pol_alpha_B_N PF08418.5 EEQ73672.1 - 2.1 7.8 7.1 5.3 6.5 0.1 2.3 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Ribosomal_L22e PF01776.12 EEQ73673.1 - 3.3e-50 168.7 0.2 3.8e-50 168.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family GSHPx PF00255.14 EEQ73674.1 - 6.1e-39 131.7 0.0 9.7e-39 131.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EEQ73674.1 - 0.0027 17.3 0.0 0.0048 16.5 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family DUF4174 PF13778.1 EEQ73674.1 - 0.033 14.2 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) Redoxin PF08534.5 EEQ73674.1 - 0.076 12.5 0.1 0.14 11.7 0.1 1.7 1 1 0 1 1 1 0 Redoxin SCO1-SenC PF02630.9 EEQ73674.1 - 0.12 12.0 0.0 0.65 9.6 0.0 1.9 2 0 0 2 2 2 0 SCO1/SenC Translin PF01997.11 EEQ73675.1 - 6.4e-51 172.8 0.2 7.8e-51 172.5 0.1 1.1 1 0 0 1 1 1 1 Translin family HR1 PF02185.11 EEQ73675.1 - 0.0046 16.6 0.2 0.014 15.1 0.2 1.8 1 0 0 1 1 1 1 Hr1 repeat DUF4456 PF14644.1 EEQ73675.1 - 0.025 13.7 0.3 0.072 12.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4456) GMP_synt_C PF00958.17 EEQ73675.1 - 0.031 13.9 0.1 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 GMP synthase C terminal domain Pcc1 PF09341.5 EEQ73676.1 - 3.4e-23 81.4 1.4 1.5e-21 76.2 1.0 2.2 1 1 0 1 1 1 1 Transcription factor Pcc1 DSPn PF14671.1 EEQ73677.1 - 1.1e-43 148.6 0.0 4.3e-40 136.9 0.0 3.2 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EEQ73677.1 - 9.3e-17 60.8 0.0 3.6e-16 58.9 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EEQ73677.1 - 5.5e-06 25.8 0.0 9.4e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EEQ73677.1 - 0.076 13.2 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EEQ73677.1 - 0.078 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Abhydrolase_3 PF07859.8 EEQ73680.1 - 8.9e-19 67.8 0.0 1.2e-17 64.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold FAD_binding_4 PF01565.18 EEQ73681.1 - 4.1e-15 55.4 0.4 7.1e-15 54.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Homeobox PF00046.24 EEQ73683.1 - 2.8e-15 55.6 3.1 5.7e-15 54.6 2.1 1.6 1 0 0 1 1 1 1 Homeobox domain Amino_oxidase PF01593.19 EEQ73684.1 - 2.1e-47 162.2 0.1 2.2e-30 106.1 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EEQ73684.1 - 1.7e-14 53.6 0.1 1.3e-13 50.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EEQ73684.1 - 9.9e-06 25.7 0.3 4.5e-05 23.5 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEQ73684.1 - 3.5e-05 24.1 1.4 5.1e-05 23.5 0.3 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEQ73684.1 - 0.00034 19.2 0.1 0.0007 18.1 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 EEQ73684.1 - 0.00057 18.8 0.3 0.0012 17.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EEQ73684.1 - 0.00074 18.6 0.4 0.0012 18.0 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EEQ73684.1 - 0.00091 18.3 0.3 0.0023 17.0 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EEQ73684.1 - 0.001 18.9 0.2 0.021 14.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEQ73684.1 - 0.002 17.0 0.6 0.0028 16.5 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 EEQ73684.1 - 0.0075 15.9 0.5 0.015 14.9 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EEQ73684.1 - 0.016 14.1 0.2 0.031 13.1 0.1 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EEQ73684.1 - 0.099 11.5 0.1 0.21 10.4 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 EEQ73684.1 - 0.15 11.7 2.2 2.6 7.7 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding UvdE PF03851.9 EEQ73687.1 - 9e-111 369.3 0.0 1.2e-110 368.8 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE AT_hook PF02178.14 EEQ73687.1 - 0.028 14.0 3.6 0.099 12.3 2.5 2.0 1 0 0 1 1 1 0 AT hook motif CHZ PF09649.5 EEQ73687.1 - 0.039 13.1 0.0 0.11 11.6 0.0 1.7 1 0 0 1 1 1 0 Histone chaperone domain CHZ DUF2183 PF09949.4 EEQ73688.1 - 2.3e-32 110.8 0.0 4.6e-32 109.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Sugar_tr PF00083.19 EEQ73689.1 - 1.9e-129 432.1 28.0 2.1e-129 432.0 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ73689.1 - 1.9e-27 95.9 37.0 5.9e-21 74.5 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EEQ73689.1 - 2e-07 29.7 25.1 2.5e-06 26.1 7.1 3.3 3 1 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 EEQ73689.1 - 0.031 14.0 3.0 7.2 6.4 0.1 3.1 2 0 0 2 2 2 0 MFS_1 like family TPR_19 PF14559.1 EEQ73689.1 - 0.18 12.2 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Lig_chan PF00060.21 EEQ73689.1 - 0.46 10.2 3.5 0.46 10.2 0.1 2.6 2 1 1 3 3 3 0 Ligand-gated ion channel Dicty_CTDC PF00526.13 EEQ73691.1 - 0.75 9.7 2.8 2.2e+02 1.7 0.0 5.4 7 0 0 7 7 7 0 Dictyostelium (slime mold) repeat PI31_Prot_N PF11566.3 EEQ73692.1 - 7.1e-37 126.3 0.0 9.1e-37 126.0 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EEQ73692.1 - 2.7e-18 66.3 16.8 2.7e-18 66.3 11.7 2.4 2 1 0 2 2 2 1 PI31 proteasome regulator Metallophos PF00149.23 EEQ73693.1 - 4.6e-44 150.2 0.9 5.8e-44 149.8 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3112 PF11309.3 EEQ73695.1 - 1.2e-49 168.1 15.2 2.4e-49 167.1 1.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) Cation_efflux PF01545.16 EEQ73695.1 - 0.73 8.8 9.9 2.4 7.1 0.1 2.3 1 1 1 2 2 2 0 Cation efflux family WBS_methylT PF12589.3 EEQ73696.1 - 0.42 11.1 5.4 0.11 12.9 0.5 2.4 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome zf-C2H2 PF00096.21 EEQ73698.1 - 1.9e-06 27.8 15.3 0.0001 22.4 1.3 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ73698.1 - 0.0005 20.2 2.5 0.0005 20.2 1.7 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EEQ73698.1 - 0.0011 18.8 0.6 0.0011 18.8 0.4 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.2 EEQ73698.1 - 0.0075 16.4 0.7 0.0075 16.4 0.5 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EEQ73698.1 - 0.0083 16.2 0.4 0.0083 16.2 0.3 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.6 EEQ73698.1 - 0.19 11.4 4.4 0.12 12.1 0.7 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-H2C2_5 PF13909.1 EEQ73698.1 - 0.26 11.6 17.3 0.48 10.7 0.6 3.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain FYVE PF01363.16 EEQ73698.1 - 2.8 7.9 10.9 5.3 7.0 6.6 2.2 1 1 1 2 2 2 0 FYVE zinc finger DZR PF12773.2 EEQ73698.1 - 3.4 7.5 6.7 34 4.3 4.7 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-FCS PF06467.9 EEQ73698.1 - 7.3 6.3 9.9 33 4.2 0.1 3.4 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Abhydrolase_3 PF07859.8 EEQ73700.1 - 7.2e-15 55.1 0.1 4.5e-09 36.1 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold HAD_2 PF13419.1 EEQ73702.1 - 5.3e-14 52.8 0.0 8.1e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEQ73702.1 - 9.5e-07 29.4 0.0 3.9e-05 24.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ73702.1 - 4.7e-06 26.2 0.0 9e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like TPR_11 PF13414.1 EEQ73703.1 - 1.6e-14 53.2 2.8 5e-13 48.4 0.2 2.3 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EEQ73703.1 - 1.7e-05 24.3 3.3 0.076 12.9 0.0 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ73703.1 - 2.8e-05 23.5 1.0 0.0095 15.5 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ73703.1 - 3.4e-05 23.7 0.4 3.4e-05 23.7 0.3 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ73703.1 - 0.0023 17.5 0.1 6.6 6.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ73703.1 - 0.0049 17.3 2.5 2.2 9.1 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat Gag_p24 PF00607.15 EEQ73703.1 - 0.023 14.2 0.1 0.16 11.5 0.1 2.0 1 1 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) Apc3 PF12895.2 EEQ73703.1 - 0.03 14.4 0.3 0.065 13.3 0.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 ATP-synt_DE PF00401.15 EEQ73703.1 - 0.05 13.4 5.5 0.23 11.3 3.8 2.2 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DUF1876 PF08962.6 EEQ73703.1 - 0.19 11.4 1.3 0.63 9.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1876) WD40 PF00400.27 EEQ73705.1 - 8.3e-12 44.5 7.9 0.0086 15.9 0.0 7.7 8 0 0 8 8 8 4 WD domain, G-beta repeat Lactonase PF10282.4 EEQ73705.1 - 0.17 10.9 0.0 0.39 9.7 0.0 1.5 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Nucleoporin_FG PF13634.1 EEQ73706.1 - 2e-25 89.2 113.2 3.8e-15 56.0 36.6 3.3 1 1 1 2 2 2 2 Nucleoporin FG repeat region IncA PF04156.9 EEQ73707.1 - 0.025 14.1 0.5 0.031 13.8 0.4 1.2 1 0 0 1 1 1 0 IncA protein DUF1031 PF06275.6 EEQ73707.1 - 0.027 14.5 0.2 0.056 13.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Fib_alpha PF08702.5 EEQ73707.1 - 0.033 14.2 3.5 0.052 13.6 2.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF904 PF06005.7 EEQ73707.1 - 0.035 14.3 4.8 0.061 13.6 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) V_ATPase_I PF01496.14 EEQ73707.1 - 0.13 10.1 2.7 0.16 9.7 1.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fzo_mitofusin PF04799.8 EEQ73707.1 - 0.19 11.0 3.7 0.21 10.9 2.0 1.4 1 1 0 1 1 1 0 fzo-like conserved region Syntaxin PF00804.20 EEQ73707.1 - 0.49 10.5 7.3 0.82 9.8 4.6 1.7 1 1 1 2 2 2 0 Syntaxin XAP5 PF04921.9 EEQ73708.1 - 4.6e-74 249.0 0.0 1.2e-73 247.5 0.0 1.6 2 0 0 2 2 2 1 XAP5, circadian clock regulator DUF4604 PF15377.1 EEQ73708.1 - 0.012 15.8 5.1 0.022 14.9 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Fip1 PF05182.8 EEQ73709.1 - 4.6e-22 77.0 1.8 8e-22 76.2 1.2 1.4 1 0 0 1 1 1 1 Fip1 motif AF1Q PF15017.1 EEQ73709.1 - 0.32 10.9 6.7 0.9 9.4 4.6 1.8 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator CENP-T PF15511.1 EEQ73709.1 - 1.8 7.7 14.6 2.7 7.1 10.1 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T NOA36 PF06524.7 EEQ73709.1 - 2.6 7.2 7.5 3.9 6.6 5.2 1.1 1 0 0 1 1 1 0 NOA36 protein Cpn10 PF00166.16 EEQ73710.1 - 2e-29 101.3 0.0 2.2e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit TauD PF02668.11 EEQ73713.1 - 1.7e-44 152.4 0.0 2.2e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family zf-C3HC4_3 PF13920.1 EEQ73714.1 - 4.9e-06 26.1 8.7 8.7e-06 25.3 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UL2 PF08196.6 EEQ73714.1 - 0.033 13.9 0.7 0.077 12.7 0.5 1.5 1 0 0 1 1 1 0 UL2 protein ThiF PF00899.16 EEQ73715.1 - 1.8e-13 50.4 0.0 2e-11 43.8 0.0 2.3 2 0 0 2 2 2 2 ThiF family Rib_5-P_isom_A PF06026.9 EEQ73716.1 - 2.6e-37 127.8 0.0 4.8e-33 113.8 0.0 2.1 2 0 0 2 2 2 2 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) WD40 PF00400.27 EEQ73717.1 - 4e-24 83.5 4.7 3.4e-05 23.5 0.5 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ATP_bind_1 PF03029.12 EEQ73718.1 - 1.6e-75 253.7 0.0 1.9e-75 253.4 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 EEQ73718.1 - 0.00029 19.6 0.0 0.00059 18.7 0.0 1.4 1 0 0 1 1 1 1 ArgK protein AAA_10 PF12846.2 EEQ73718.1 - 0.0011 18.5 0.0 0.0079 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain CbiA PF01656.18 EEQ73718.1 - 0.002 17.5 0.0 0.0056 16.0 0.0 1.7 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.1 EEQ73718.1 - 0.0024 17.3 0.0 0.0047 16.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EEQ73718.1 - 0.004 17.9 2.9 0.006 17.3 0.3 2.4 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EEQ73718.1 - 0.01 15.7 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEQ73718.1 - 0.047 13.6 0.0 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain KTI12 PF08433.5 EEQ73718.1 - 0.049 12.8 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MMR_HSR1 PF01926.18 EEQ73718.1 - 0.053 13.4 0.0 0.21 11.5 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase Fer4_NifH PF00142.13 EEQ73718.1 - 0.18 10.9 0.4 0.74 8.9 0.0 1.9 1 1 1 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RNase_P_Rpp14 PF01900.14 EEQ73719.1 - 2.6e-36 123.7 0.0 3.5e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family CoA_binding PF02629.14 EEQ73720.1 - 4.4e-19 68.7 0.1 1.6e-18 67.0 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Citrate_synt PF00285.16 EEQ73720.1 - 6e-18 64.7 0.0 4e-15 55.4 0.0 3.1 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 EEQ73720.1 - 6.2e-15 55.1 0.1 1.1e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EEQ73720.1 - 6.2e-07 29.0 0.0 1.6e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CEP1-DNA_bind PF09287.5 EEQ73720.1 - 0.21 10.9 0.0 0.44 9.9 0.0 1.4 1 0 0 1 1 1 0 CEP-1, DNA binding ATP-grasp_2 PF08442.5 EEQ73721.1 - 2.8e-08 33.3 0.0 4.2e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.7 EEQ73721.1 - 0.077 10.7 0.0 0.11 10.3 0.0 1.2 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) CFEM PF05730.6 EEQ73724.1 - 2.3e-16 59.3 8.0 3.1e-16 58.9 5.5 1.2 1 0 0 1 1 1 1 CFEM domain MGC-24 PF05283.6 EEQ73724.1 - 0.011 15.4 6.3 0.013 15.2 4.3 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) PT PF04886.7 EEQ73724.1 - 0.13 11.5 19.7 0.64 9.3 13.7 2.2 1 1 0 1 1 1 0 PT repeat DNA_pol_delta_4 PF04081.8 EEQ73726.1 - 7.5e-28 97.3 0.4 1e-27 96.8 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Amidase PF01425.16 EEQ73727.1 - 9.2e-93 311.4 0.0 1.1e-92 311.2 0.0 1.0 1 0 0 1 1 1 1 Amidase ORC6 PF05460.8 EEQ73728.1 - 9.2e-57 192.7 0.4 1.5e-56 191.9 0.3 1.4 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) DUF2419 PF10343.4 EEQ73729.1 - 3.2e-136 453.2 0.0 3.9e-136 452.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) ThiF PF00899.16 EEQ73730.1 - 7.8e-41 139.0 0.0 1.5e-40 138.2 0.0 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EEQ73730.1 - 3.7e-29 100.1 1.3 8.2e-29 98.9 0.9 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 EEQ73730.1 - 1.7e-21 76.1 1.1 4.4e-21 74.7 0.8 1.8 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 EEQ73730.1 - 1.9e-19 68.7 0.6 1.9e-19 68.7 0.4 2.5 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 EEQ73730.1 - 0.00081 19.6 0.2 0.0032 17.7 0.0 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EEQ73730.1 - 0.0038 17.3 0.1 0.014 15.5 0.1 1.9 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EEQ73730.1 - 0.13 12.6 0.1 2.5 8.5 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 EEQ73731.1 - 1.2e-23 83.8 0.8 4.8e-11 42.8 0.0 2.6 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ73731.1 - 7.5e-10 38.9 0.3 4.7e-07 29.8 0.1 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ73731.1 - 6.6e-07 29.1 0.3 2.1e-05 24.2 0.0 3.1 2 1 1 3 3 3 1 KR domain Polysacc_synt_2 PF02719.10 EEQ73731.1 - 0.0057 15.6 0.0 0.012 14.5 0.0 1.5 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EEQ73731.1 - 0.0087 15.8 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 EEQ73731.1 - 0.0091 16.1 0.0 0.027 14.5 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EEQ73731.1 - 0.017 14.5 0.6 0.26 10.6 0.1 2.4 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EEQ73731.1 - 0.024 14.6 0.1 0.092 12.7 0.0 1.9 2 0 0 2 2 2 0 NADH(P)-binding Skp1_POZ PF03931.10 EEQ73732.1 - 3.2e-11 43.1 0.0 4e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain tRNA_int_end_N2 PF12928.2 EEQ73733.1 - 6.8e-34 115.1 0.0 1.1e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EEQ73733.1 - 0.0037 16.7 0.0 0.0075 15.7 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Peptidase_M26_C PF07580.9 EEQ73734.1 - 0.034 12.4 0.0 0.037 12.3 0.0 1.0 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region FAD_binding_4 PF01565.18 EEQ73734.1 - 0.075 12.5 0.1 0.2 11.1 0.1 1.6 1 1 1 2 2 2 0 FAD binding domain Arrestin_C PF02752.17 EEQ73735.1 - 4.6e-13 49.4 0.1 1.3e-12 47.9 0.0 1.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.16 EEQ73736.1 - 4.8e-36 124.3 0.0 5.9e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-ZPR1 PF03367.8 EEQ73737.1 - 1.5e-102 339.5 0.0 4.1e-50 169.0 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zf-ISL3 PF14690.1 EEQ73737.1 - 0.69 9.9 6.5 19 5.4 0.2 3.4 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Elf1 PF05129.8 EEQ73737.1 - 3.9 7.2 6.4 18 5.1 0.1 2.6 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like Rpr2 PF04032.11 EEQ73738.1 - 8.3e-06 25.5 1.4 8.3e-06 25.5 1.0 1.9 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain MFS_1 PF07690.11 EEQ73739.1 - 1.1e-36 126.2 30.9 1.1e-36 126.2 21.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ73741.1 - 8.5e-123 410.2 25.3 9.7e-123 410.0 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ73741.1 - 1.7e-26 92.8 31.8 6.5e-17 61.2 6.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3154 PF11351.3 EEQ73741.1 - 0.11 12.2 1.8 0.66 9.7 0.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3154) Histone PF00125.19 EEQ73742.1 - 1.1e-21 76.7 0.0 1.4e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEQ73742.1 - 2.6e-06 27.3 0.0 3.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Abhydrolase_3 PF07859.8 EEQ73743.1 - 1.5e-13 50.7 0.0 2e-11 43.8 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEQ73743.1 - 0.089 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pho88 PF10032.4 EEQ73744.1 - 1e-81 272.7 0.1 1.1e-81 272.6 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF2576 PF10845.3 EEQ73744.1 - 0.023 13.8 0.0 0.046 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Gp_dh_C PF02800.15 EEQ73745.1 - 6.8e-75 249.7 0.0 1.2e-74 249.0 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EEQ73745.1 - 3.1e-61 205.7 0.4 5e-61 205.0 0.3 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EEQ73745.1 - 0.00036 20.4 0.3 0.0028 17.5 0.0 2.4 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 EEQ73745.1 - 0.0033 17.9 0.1 0.33 11.4 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold ADH_zinc_N PF00107.21 EEQ73745.1 - 0.038 13.5 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Hist_deacetyl PF00850.14 EEQ73746.1 - 1.1e-96 323.7 0.0 1.8e-96 323.0 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EEQ73746.1 - 3.5e-48 163.3 0.2 5.4e-48 162.7 0.2 1.3 1 0 0 1 1 1 1 Arb2 domain KAR9 PF08580.5 EEQ73746.1 - 2.2 6.4 3.0 3.2 5.9 2.1 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 HSF_DNA-bind PF00447.12 EEQ73747.1 - 2.2e-29 101.6 0.4 4.7e-29 100.6 0.3 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding TMF_DNA_bd PF12329.3 EEQ73747.1 - 0.035 13.9 4.8 0.092 12.5 0.7 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Lsm_interact PF05391.6 EEQ73747.1 - 0.052 13.0 0.1 0.18 11.3 0.1 2.0 1 0 0 1 1 1 0 Lsm interaction motif CHD5 PF04420.9 EEQ73747.1 - 0.2 11.3 0.3 0.48 10.0 0.2 1.6 1 0 0 1 1 1 0 CHD5-like protein Aldo_ket_red PF00248.16 EEQ73748.1 - 2.5e-23 82.3 0.0 3.4e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family SANTA PF09133.5 EEQ73748.1 - 0.027 14.4 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 SANTA (SANT Associated) EF-hand_4 PF12763.2 EEQ73749.1 - 1.8e-26 91.9 0.0 1.6e-13 50.2 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.15 EEQ73749.1 - 2.8e-10 39.4 0.6 6.2e-10 38.3 0.4 1.6 1 0 0 1 1 1 1 WH2 motif EF-hand_7 PF13499.1 EEQ73749.1 - 2.9e-05 24.0 1.0 0.0048 17.0 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain pair DUF1720 PF08226.6 EEQ73749.1 - 0.0011 18.9 33.7 0.0011 18.9 23.4 7.3 5 2 2 7 7 7 3 Domain of unknown function (DUF1720) EF-hand_1 PF00036.27 EEQ73749.1 - 0.0031 16.6 0.0 0.44 9.9 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EEQ73749.1 - 0.1 12.2 0.0 0.45 10.1 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair Na_Ca_ex PF01699.19 EEQ73750.1 - 1.6e-45 154.1 42.0 3.8e-26 91.3 9.8 3.1 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Herpes_gE PF02480.11 EEQ73750.1 - 0.062 11.5 0.0 0.17 10.1 0.0 1.7 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Vpu PF00558.14 EEQ73750.1 - 0.19 11.2 0.1 0.52 9.9 0.0 1.7 1 0 0 1 1 1 0 Vpu protein Cnd2 PF05786.9 EEQ73751.1 - 6.3e-228 758.9 1.5 8e-228 758.5 1.0 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 PBP1_TM PF14812.1 EEQ73751.1 - 0.7 10.2 5.6 3.6 7.9 3.9 2.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tetraspannin PF00335.15 EEQ73752.1 - 0.00089 18.5 3.4 0.0014 17.9 2.3 1.3 1 0 0 1 1 1 1 Tetraspanin family DUF1129 PF06570.6 EEQ73752.1 - 0.0034 16.7 0.1 0.0034 16.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1129) GPI2 PF06432.6 EEQ73752.1 - 0.084 12.2 2.3 4.5 6.5 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase Zip PF02535.17 EEQ73752.1 - 0.18 10.7 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3609 PF12259.3 EEQ73752.1 - 0.55 8.8 1.9 0.58 8.7 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3609) DUF2254 PF10011.4 EEQ73752.1 - 3.7 5.9 4.6 6 5.2 3.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) ADK PF00406.17 EEQ73754.1 - 6.6e-40 136.4 0.1 9.3e-21 74.2 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase AAA_18 PF13238.1 EEQ73754.1 - 7e-09 36.0 0.0 1.3e-08 35.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEQ73754.1 - 2e-06 27.7 0.2 3.4e-05 23.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEQ73754.1 - 7.7e-06 26.7 0.0 1.3e-05 25.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EEQ73754.1 - 0.0013 18.1 0.4 0.69 9.2 0.0 2.4 2 1 0 2 2 2 2 Thymidylate kinase NTPase_1 PF03266.10 EEQ73754.1 - 0.062 13.0 0.8 1.5 8.4 0.1 2.7 3 0 0 3 3 3 0 NTPase AAA_19 PF13245.1 EEQ73754.1 - 0.086 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain PCI PF01399.22 EEQ73755.1 - 1.1e-10 41.8 0.0 2.4e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 PCI domain DUF4631 PF15450.1 EEQ73755.1 - 0.0014 17.0 0.3 0.0024 16.2 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4631) IFT57 PF10498.4 EEQ73755.1 - 0.013 14.2 0.1 0.028 13.1 0.0 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 K_channel_TID PF07941.6 EEQ73755.1 - 0.061 13.5 7.4 0.16 12.2 5.1 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain 4HBT PF03061.17 EEQ73757.1 - 1.1e-10 41.4 0.1 1.9e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EEQ73758.1 - 4.1e-51 174.1 0.6 4.8e-51 173.9 0.4 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Glyco_transf_20 PF00982.16 EEQ73759.1 - 3.3e-162 540.2 0.4 5e-162 539.6 0.1 1.4 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EEQ73759.1 - 1.9e-41 141.5 0.1 3e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.6 EEQ73759.1 - 0.0081 15.6 0.2 0.014 14.8 0.2 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain DUF4441 PF14536.1 EEQ73759.1 - 0.13 12.2 0.5 0.28 11.1 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) Stk19 PF10494.4 EEQ73760.1 - 8.4e-73 244.8 0.0 1e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Ribonuclease_3 PF00636.21 EEQ73761.1 - 0.00012 22.5 0.2 0.0011 19.3 0.1 2.1 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EEQ73761.1 - 0.00032 20.6 0.0 0.0004 20.3 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Methyltransf_23 PF13489.1 EEQ73762.1 - 3.5e-21 75.5 0.0 6.2e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ73762.1 - 7.2e-09 36.0 0.0 1.7e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ73762.1 - 1.7e-08 35.0 0.1 4.7e-07 30.3 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ73762.1 - 2.7e-07 30.2 0.0 0.0042 16.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ73762.1 - 2.3e-06 27.9 0.0 5.6e-05 23.5 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEQ73762.1 - 0.0031 16.6 0.0 0.0082 15.2 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 EEQ73762.1 - 0.0054 17.0 0.0 0.023 15.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EEQ73762.1 - 0.0099 15.8 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EEQ73762.1 - 0.026 13.6 0.0 0.75 8.8 0.0 2.5 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family MTS PF05175.9 EEQ73762.1 - 0.11 11.8 0.0 0.39 10.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.8 EEQ73762.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) VP40 PF07447.7 EEQ73762.1 - 0.14 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Matrix protein VP40 DUF3074 PF11274.3 EEQ73763.1 - 7.2e-45 152.8 0.0 8.7e-45 152.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) zf-H2C2_2 PF13465.1 EEQ73764.1 - 1.4e-12 47.1 16.6 1.1e-07 31.7 1.3 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EEQ73764.1 - 7.2e-09 35.4 27.7 0.0079 16.4 0.1 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ73764.1 - 1.5e-05 24.9 26.0 0.019 15.2 0.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EEQ73764.1 - 0.062 13.2 0.1 0.062 13.2 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger DZR PF12773.2 EEQ73764.1 - 0.42 10.4 6.6 5.1 6.9 4.6 2.2 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 EEQ73764.1 - 0.87 9.5 9.8 2.5 8.1 2.0 3.0 1 1 1 2 2 2 0 Zinc ribbon domain zf-RING_3 PF14369.1 EEQ73764.1 - 3.2 7.8 7.2 17 5.4 0.1 2.9 2 1 0 2 2 2 0 zinc-finger DUF2852 PF11014.3 EEQ73765.1 - 0.25 11.2 3.6 0.34 10.8 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) SET PF00856.23 EEQ73767.1 - 0.003 17.8 0.0 0.93 9.7 0.0 2.7 2 0 0 2 2 2 2 SET domain TPR_11 PF13414.1 EEQ73767.1 - 0.0039 16.8 0.2 0.0096 15.5 0.1 1.7 1 0 0 1 1 1 1 TPR repeat SAP PF02037.22 EEQ73767.1 - 0.16 11.4 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 SAP domain DUF1800 PF08811.6 EEQ73768.1 - 0.043 12.7 0.0 0.072 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) ADH_N PF08240.7 EEQ73770.1 - 9e-25 86.5 1.6 9e-25 86.5 1.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ73770.1 - 4.1e-19 68.4 0.1 6.2e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase p450 PF00067.17 EEQ73773.1 - 1.6e-72 244.5 0.0 2e-72 244.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 EEQ73774.1 - 7.4e-45 153.1 9.9 1.3e-32 112.9 0.0 3.3 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ73774.1 - 2.4e-31 108.7 6.3 4.1e-23 81.7 0.0 3.2 2 1 1 3 3 2 2 Protein tyrosine kinase OmpH PF03938.9 EEQ73774.1 - 0.0037 17.2 21.0 0.0074 16.2 14.5 1.5 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) CENP-U PF13097.1 EEQ73774.1 - 0.0073 16.2 12.5 0.0073 16.2 8.7 2.2 2 0 0 2 2 2 1 CENP-A nucleosome associated complex (NAC) subunit Ycf1 PF05758.7 EEQ73774.1 - 0.035 11.8 6.5 0.048 11.3 4.5 1.1 1 0 0 1 1 1 0 Ycf1 DUF4407 PF14362.1 EEQ73774.1 - 0.41 9.5 11.4 0.7 8.7 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-DHHC PF01529.15 EEQ73774.1 - 0.63 9.4 2.8 0.97 8.8 2.0 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase Plasmodium_Vir PF05795.6 EEQ73774.1 - 1.1 8.3 2.6 2.2 7.3 1.8 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FAM176 PF14851.1 EEQ73774.1 - 1.5 8.4 4.7 5.3 6.7 3.3 2.0 1 0 0 1 1 1 0 FAM176 family GBP_C PF02841.9 EEQ73774.1 - 2.3 7.3 22.0 4.1 6.4 15.2 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain BAF1_ABF1 PF04684.8 EEQ73774.1 - 2.7 6.7 32.0 4.8 5.9 22.2 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Sec62 PF03839.11 EEQ73774.1 - 3 7.1 5.7 5.6 6.3 4.0 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Glyco_transf_15 PF01793.11 EEQ73774.1 - 3.8 6.3 9.2 6.4 5.6 6.4 1.3 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF4175 PF13779.1 EEQ73774.1 - 5.7 4.5 44.8 8.6 3.9 31.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) V_ATPase_I PF01496.14 EEQ73774.1 - 6.6 4.4 6.1 9.1 3.9 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM60A PF15396.1 EEQ73774.1 - 6.6 6.4 12.7 1.6 8.4 6.0 2.0 2 0 0 2 2 2 0 Protein Family FAM60A UBA_4 PF14555.1 EEQ73776.1 - 2.2e-14 52.7 0.0 4.1e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.1 EEQ73776.1 - 1.8e-13 50.2 0.0 3.6e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 EEQ73776.1 - 5.4e-08 32.7 0.0 2.9e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 UBX domain Thioredox_DsbH PF03190.10 EEQ73776.1 - 0.029 14.0 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF255 AAA_22 PF13401.1 EEQ73777.1 - 3.8e-14 52.9 0.0 8.4e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEQ73777.1 - 1.1e-13 51.5 0.4 9.4e-13 48.5 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EEQ73777.1 - 3.5e-13 49.8 0.0 6.3e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.6 EEQ73777.1 - 5.4e-05 22.8 0.0 0.00024 20.7 0.0 2.0 2 0 0 2 2 2 1 CDC6, C terminal RNA_helicase PF00910.17 EEQ73777.1 - 0.001 19.1 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.7 EEQ73777.1 - 0.0011 18.6 0.1 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PIF1 PF05970.9 EEQ73777.1 - 0.0051 15.8 0.0 0.0076 15.2 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_17 PF13207.1 EEQ73777.1 - 0.0063 17.3 0.0 0.011 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ73777.1 - 0.018 14.8 0.0 0.053 13.2 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain TIP49 PF06068.8 EEQ73777.1 - 0.018 13.7 0.0 0.027 13.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_33 PF13671.1 EEQ73777.1 - 0.027 14.3 0.0 0.074 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EEQ73777.1 - 0.035 13.0 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF815 PF05673.8 EEQ73777.1 - 0.055 12.3 0.0 0.091 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) KAP_NTPase PF07693.9 EEQ73777.1 - 0.067 12.1 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain RuvB_N PF05496.7 EEQ73777.1 - 0.11 11.4 0.0 0.24 10.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EEQ73777.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain p450 PF00067.17 EEQ73778.1 - 9.1e-33 113.4 0.0 3.2e-29 101.7 0.0 3.0 1 1 1 2 2 2 2 Cytochrome P450 Vpu PF00558.14 EEQ73778.1 - 0.21 11.1 0.7 0.39 10.2 0.5 1.3 1 0 0 1 1 1 0 Vpu protein RhoGAP PF00620.22 EEQ73779.1 - 1.5e-15 57.1 0.2 4.5e-15 55.5 0.2 1.8 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EEQ73779.1 - 2.1e-13 50.2 0.1 1e-12 48.0 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 EEQ73779.1 - 9e-12 44.5 0.0 7.2e-11 41.6 0.0 2.3 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Phage_Gp14 PF10666.4 EEQ73779.1 - 0.044 13.6 1.6 0.058 13.2 0.1 1.8 2 0 0 2 2 2 0 Phage protein Gp14 Acetyltransf_3 PF13302.1 EEQ73781.1 - 0.055 13.6 0.0 0.081 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AMP-binding PF00501.23 EEQ73782.1 - 6.7e-62 209.2 0.0 1.3e-61 208.3 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme AP_endonuc_2 PF01261.19 EEQ73784.1 - 6.7e-10 38.6 0.0 9.9e-10 38.0 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AA_permease PF00324.16 EEQ73786.1 - 5.2e-142 473.5 40.9 6.5e-142 473.2 28.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ73786.1 - 1.2e-35 122.9 39.0 1.6e-35 122.5 27.0 1.0 1 0 0 1 1 1 1 Amino acid permease Suf PF05843.9 EEQ73787.1 - 0.86 9.2 4.1 1.1 8.9 2.8 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) LSM PF01423.17 EEQ73788.1 - 3.8e-20 71.2 0.0 4.2e-20 71.0 0.0 1.0 1 0 0 1 1 1 1 LSM domain DNA_pol_A_exo1 PF01612.15 EEQ73789.1 - 5.4e-14 52.0 0.0 9.2e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Pex2_Pex12 PF04757.9 EEQ73790.1 - 2.6e-44 151.3 5.2 3.5e-44 150.9 3.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EEQ73790.1 - 1.7e-11 43.7 9.6 2.7e-11 43.0 6.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEQ73790.1 - 5.1e-11 42.4 9.1 8.3e-11 41.7 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ73790.1 - 7.7e-11 41.4 7.6 1.2e-10 40.8 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ73790.1 - 3.7e-10 39.3 5.5 5.8e-10 38.6 3.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ73790.1 - 4.3e-08 32.7 7.1 6.7e-08 32.1 5.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EEQ73790.1 - 1.3e-06 28.1 8.1 2.2e-06 27.4 5.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EEQ73790.1 - 4.9e-06 26.1 2.0 1.5e-05 24.5 1.4 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EEQ73790.1 - 8.7e-06 25.7 6.8 3e-05 24.0 4.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EEQ73790.1 - 0.0015 18.2 2.9 0.003 17.3 2.0 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.3 EEQ73790.1 - 0.019 14.4 4.3 0.035 13.6 3.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 EEQ73790.1 - 0.074 12.9 4.4 0.17 11.7 2.7 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EEQ73790.1 - 0.12 11.9 8.3 0.23 11.0 5.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE PF01363.16 EEQ73790.1 - 0.81 9.6 6.4 2.4 8.1 4.4 1.8 1 1 0 1 1 1 0 FYVE zinc finger IBR PF01485.16 EEQ73790.1 - 1.5 8.7 7.8 4.6 7.1 5.3 1.8 1 1 0 1 1 1 0 IBR domain EXS PF03124.9 EEQ73791.1 - 3.8e-99 331.9 8.4 4.4e-99 331.7 5.8 1.0 1 0 0 1 1 1 1 EXS family Mucin PF01456.12 EEQ73792.1 - 0.014 15.2 14.3 0.014 15.2 9.9 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF4131 PF13567.1 EEQ73792.1 - 0.059 12.7 0.3 1.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ATP-synt_S1 PF05827.7 EEQ73793.1 - 1.3e-40 139.4 0.0 1.6e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) CMAS PF02353.15 EEQ73794.1 - 1.9e-63 214.1 0.0 2.3e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EEQ73794.1 - 3.5e-12 46.3 0.0 6e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ73794.1 - 4.7e-07 30.2 0.0 9.3e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ73794.1 - 0.00011 22.2 0.0 0.00029 20.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ73794.1 - 0.00025 21.5 0.0 0.00067 20.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ73794.1 - 0.00029 20.4 0.0 0.00047 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ73794.1 - 0.00031 21.1 0.1 0.001 19.4 0.0 1.9 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ73794.1 - 0.00051 20.3 0.0 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ73794.1 - 0.0011 18.4 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.8 EEQ73794.1 - 0.003 16.9 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.14 EEQ73794.1 - 0.0038 16.7 0.0 0.0059 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EEQ73794.1 - 0.035 13.4 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FtsJ PF01728.14 EEQ73794.1 - 0.088 12.7 0.1 0.26 11.2 0.0 1.7 1 1 1 2 2 2 0 FtsJ-like methyltransferase RE_AccI PF09545.5 EEQ73795.1 - 0.17 10.3 0.0 0.24 9.8 0.0 1.1 1 0 0 1 1 1 0 AccI restriction endonuclease Tropomyosin_1 PF12718.2 EEQ73796.1 - 8.9e-50 168.2 36.1 1.1e-49 167.9 25.0 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EEQ73796.1 - 2.7e-10 39.7 33.9 5e-05 22.4 8.7 2.5 1 1 1 2 2 2 2 Tropomyosin Laminin_II PF06009.7 EEQ73796.1 - 0.00078 19.2 6.8 0.00078 19.2 4.7 2.1 1 1 1 2 2 2 1 Laminin Domain II KLRAQ PF10205.4 EEQ73796.1 - 0.00091 19.2 11.0 0.00091 19.2 7.6 2.8 1 1 2 3 3 3 1 Predicted coiled-coil domain-containing protein DUF4200 PF13863.1 EEQ73796.1 - 0.0026 17.6 34.7 0.027 14.4 11.5 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4200) KAR9 PF08580.5 EEQ73796.1 - 0.0027 16.0 0.9 0.0027 16.0 0.7 2.2 1 1 0 2 2 2 1 Yeast cortical protein KAR9 Myosin_tail_1 PF01576.14 EEQ73796.1 - 0.0037 15.0 34.7 0.013 13.2 2.3 2.0 1 1 1 2 2 2 2 Myosin tail EzrA PF06160.7 EEQ73796.1 - 0.0061 14.7 5.5 0.0061 14.7 3.8 2.0 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.4 EEQ73796.1 - 0.0077 16.0 34.9 0.016 15.0 4.1 3.1 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.5 EEQ73796.1 - 0.0089 16.1 19.6 0.27 11.3 4.7 2.2 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.3 EEQ73796.1 - 0.012 15.3 29.3 0.044 13.5 11.6 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EEQ73796.1 - 0.021 14.6 37.1 1.5 8.6 14.0 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EEQ73796.1 - 0.025 14.1 32.4 0.51 9.9 22.5 2.2 1 1 0 1 1 1 0 IncA protein Mod_r PF07200.8 EEQ73796.1 - 0.026 14.4 28.0 0.52 10.2 13.2 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF869 PF05911.6 EEQ73796.1 - 0.034 12.4 26.1 0.31 9.2 6.0 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) TPR_MLP1_2 PF07926.7 EEQ73796.1 - 0.036 13.8 35.7 0.068 12.9 7.3 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.6 EEQ73796.1 - 0.037 13.8 31.4 0.86 9.3 6.9 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 EEQ73796.1 - 0.04 12.9 35.6 0.74 8.8 13.2 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 BLOC1_2 PF10046.4 EEQ73796.1 - 0.045 13.8 23.1 0.31 11.2 0.7 3.2 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LPP PF04728.8 EEQ73796.1 - 0.047 13.5 1.8 3 7.7 0.1 2.9 2 1 1 3 3 3 0 Lipoprotein leucine-zipper ERM PF00769.14 EEQ73796.1 - 0.047 13.2 39.0 0.59 9.6 12.9 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family IFT46_B_C PF12317.3 EEQ73796.1 - 0.058 12.7 9.3 0.016 14.6 4.0 1.6 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Spc7 PF08317.6 EEQ73796.1 - 0.071 11.7 28.1 0.19 10.3 7.3 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Cast PF10174.4 EEQ73796.1 - 0.079 11.0 30.0 0.086 10.8 20.8 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Striatin PF08232.7 EEQ73796.1 - 0.08 13.2 28.3 0.49 10.6 12.0 2.2 1 1 1 2 2 2 0 Striatin family MscS_porin PF12795.2 EEQ73796.1 - 0.098 11.9 29.7 0.29 10.4 15.7 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Reo_sigmaC PF04582.7 EEQ73796.1 - 0.1 11.7 4.4 1.8 7.6 0.1 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Herpes_pp85 PF04637.7 EEQ73796.1 - 0.11 10.7 5.7 0.056 11.7 2.5 1.5 1 1 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) FlaC_arch PF05377.6 EEQ73796.1 - 0.12 12.3 16.1 0.78 9.6 0.4 4.3 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF745 PF05335.8 EEQ73796.1 - 0.12 11.9 22.6 0.54 9.7 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) FlxA PF14282.1 EEQ73796.1 - 0.12 12.3 21.8 3.8 7.5 0.1 2.6 1 1 0 2 2 2 0 FlxA-like protein NPV_P10 PF05531.7 EEQ73796.1 - 0.14 12.4 7.9 1.4 9.2 0.0 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein GAS PF13851.1 EEQ73796.1 - 0.16 11.1 32.7 0.8 8.8 14.8 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding WXG100 PF06013.7 EEQ73796.1 - 0.2 11.6 17.2 0.25 11.3 0.5 3.4 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Cortex-I_coil PF09304.5 EEQ73796.1 - 0.31 11.1 32.1 0.2 11.7 8.3 3.0 1 1 2 3 3 3 0 Cortexillin I, coiled coil Syntaxin-6_N PF09177.6 EEQ73796.1 - 0.34 11.3 20.3 2 8.8 2.6 3.1 1 1 2 3 3 3 0 Syntaxin 6, N-terminal ADIP PF11559.3 EEQ73796.1 - 0.34 10.7 33.9 2.2 8.1 8.1 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.4 EEQ73796.1 - 0.48 10.3 28.3 0.74 9.7 14.2 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF2353 PF09789.4 EEQ73796.1 - 0.53 9.4 26.0 2.8 7.1 18.0 1.8 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF4140 PF13600.1 EEQ73796.1 - 0.64 10.5 22.8 1.2 9.6 4.3 3.1 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) NABP PF07990.7 EEQ73796.1 - 0.78 8.9 6.5 0.83 8.8 4.5 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP MAD PF05557.8 EEQ73796.1 - 0.89 7.5 31.9 1.2 7.1 22.1 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF812 PF05667.6 EEQ73796.1 - 0.92 7.9 27.3 5 5.5 17.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Atg14 PF10186.4 EEQ73796.1 - 1.1 8.1 27.4 0.85 8.5 14.1 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_1 PF00170.16 EEQ73796.1 - 1.5 8.8 32.8 1.1 9.2 0.9 4.8 2 1 2 4 4 3 0 bZIP transcription factor V_ATPase_I PF01496.14 EEQ73796.1 - 1.7 6.4 21.5 2.4 5.9 14.5 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Uds1 PF15456.1 EEQ73796.1 - 1.7 8.6 28.3 3.8 7.5 1.2 3.0 1 1 2 3 3 3 0 Up-regulated During Septation HAP1_N PF04849.8 EEQ73796.1 - 1.8 7.4 29.5 16 4.3 13.3 2.5 1 1 0 1 1 1 0 HAP1 N-terminal conserved region THOC7 PF05615.8 EEQ73796.1 - 2 8.6 31.0 0.78 10.0 3.0 2.9 1 1 2 3 3 3 0 Tho complex subunit 7 HSP70 PF00012.15 EEQ73796.1 - 2.1 6.1 19.6 2.4 5.9 13.6 1.2 1 0 0 1 1 1 0 Hsp70 protein DUF3584 PF12128.3 EEQ73796.1 - 2.2 5.5 30.5 6.9 3.8 21.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF342 PF03961.8 EEQ73796.1 - 2.3 6.5 27.3 0.38 9.1 6.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Lebercilin PF15619.1 EEQ73796.1 - 2.3 7.6 35.0 6.1 6.2 10.8 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF972 PF06156.8 EEQ73796.1 - 2.4 8.5 27.5 1.6 9.1 8.5 2.9 1 1 1 2 2 1 0 Protein of unknown function (DUF972) DUF4201 PF13870.1 EEQ73796.1 - 2.9 7.3 28.5 16 4.8 19.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Fmp27_WPPW PF10359.4 EEQ73796.1 - 3.4 5.9 25.9 1.2 7.4 7.3 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Prefoldin_2 PF01920.15 EEQ73796.1 - 3.7 7.3 34.1 0.33 10.7 1.6 4.1 2 1 2 4 4 4 0 Prefoldin subunit AAA_13 PF13166.1 EEQ73796.1 - 4.6 5.5 25.2 18 3.5 17.5 1.9 1 1 0 1 1 1 0 AAA domain Mnd1 PF03962.10 EEQ73796.1 - 5.2 6.6 32.5 4.4 6.9 8.2 2.1 1 1 1 2 2 2 0 Mnd1 family Sipho_Gp157 PF05565.6 EEQ73796.1 - 5.2 6.6 22.1 3 7.3 5.1 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 DUF3450 PF11932.3 EEQ73796.1 - 6.7 5.8 27.2 4.8 6.3 3.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Rootletin PF15035.1 EEQ73796.1 - 7.1 6.5 32.6 9.2 6.1 6.6 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion CCDC155 PF14662.1 EEQ73796.1 - 8.6 5.9 34.9 5.9 6.4 11.7 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DUF1664 PF07889.7 EEQ73796.1 - 9.8 6.0 14.6 16 5.2 0.2 3.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DUF3461 PF11944.3 EEQ73796.1 - 9.9 6.0 14.2 7.2 6.4 4.1 2.5 2 1 1 3 3 2 0 Protein of unknown function (DUF3461) Nop25 PF09805.4 EEQ73797.1 - 1.1e-37 129.1 13.6 1.1e-37 129.1 9.4 3.1 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) EIIBC-GUT_N PF03612.9 EEQ73797.1 - 0.51 9.9 3.8 11 5.6 0.1 2.7 2 1 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Nop14 PF04147.7 EEQ73797.1 - 9.2 4.0 34.8 14 3.4 24.1 1.3 1 0 0 1 1 1 0 Nop14-like family Bul1_C PF04426.7 EEQ73798.1 - 0.0017 17.6 0.0 0.003 16.7 0.0 1.4 1 0 0 1 1 1 1 Bul1 C terminus HCO3_cotransp PF00955.16 EEQ73800.1 - 1.7e-05 23.6 1.4 1.7e-05 23.6 1.0 2.9 3 0 0 3 3 3 2 HCO3- transporter family AMP-binding PF00501.23 EEQ73801.1 - 1.5e-93 313.4 0.0 1.8e-93 313.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ73801.1 - 1.4e-13 51.5 0.5 2.9e-13 50.5 0.3 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain EGF_3 PF12947.2 EEQ73802.1 - 0.0074 16.2 4.8 0.0074 16.2 3.3 4.9 10 0 0 10 10 10 1 EGF domain MCM PF00493.18 EEQ73803.1 - 1.1e-133 445.1 0.0 1.6e-133 444.6 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EEQ73803.1 - 3.7e-28 98.4 0.0 1e-27 96.9 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEQ73803.1 - 5.9e-07 28.8 0.0 5.5e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEQ73803.1 - 1.6e-05 24.6 0.0 4.7e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EEQ73803.1 - 0.0031 17.1 0.0 8.4 5.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain Mg_chelatase_2 PF13335.1 EEQ73803.1 - 0.0075 16.6 1.1 0.027 14.8 0.1 2.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA PF00004.24 EEQ73804.1 - 1.3e-53 180.7 0.0 3.3e-43 147.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EEQ73804.1 - 2.9e-12 46.4 3.4 3.4e-08 33.4 0.2 2.5 1 1 1 2 2 2 2 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EEQ73804.1 - 1.2e-08 35.1 5.0 0.00026 21.0 0.0 3.8 3 1 1 4 4 4 2 AAA ATPase domain NACHT PF05729.7 EEQ73804.1 - 1.2e-06 28.2 0.6 0.0018 17.9 0.0 3.7 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.1 EEQ73804.1 - 1.7e-06 28.1 0.5 0.083 13.0 0.0 3.9 3 1 0 3 3 2 2 AAA domain AAA_19 PF13245.1 EEQ73804.1 - 7.4e-06 25.6 0.1 0.023 14.4 0.0 3.3 3 0 0 3 3 3 2 Part of AAA domain RuvB_N PF05496.7 EEQ73804.1 - 5.3e-05 22.3 0.0 0.012 14.6 0.0 2.8 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EEQ73804.1 - 5.4e-05 23.9 0.0 0.2 12.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EEQ73804.1 - 7.4e-05 22.7 0.0 0.17 11.7 0.0 2.6 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EEQ73804.1 - 7.6e-05 22.6 0.0 0.61 9.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EEQ73804.1 - 0.00035 19.7 0.0 0.45 9.5 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 EEQ73804.1 - 0.00035 20.8 0.1 0.21 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EEQ73804.1 - 0.00067 19.1 0.1 1.2 8.5 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein UPF0079 PF02367.12 EEQ73804.1 - 0.0018 17.8 0.0 0.026 14.1 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 EEQ73804.1 - 0.002 17.1 0.3 0.2 10.5 0.0 2.4 1 1 1 2 2 2 1 KAP family P-loop domain AAA_33 PF13671.1 EEQ73804.1 - 0.002 17.9 0.0 0.4 10.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EEQ73804.1 - 0.0041 17.0 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EEQ73804.1 - 0.01 15.9 0.0 8.1 6.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.9 EEQ73804.1 - 0.011 15.3 0.1 2.2 7.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EEQ73804.1 - 0.012 15.0 3.3 12 5.2 0.1 3.8 2 2 1 4 4 4 0 AAA domain ABC_tran PF00005.22 EEQ73804.1 - 0.029 14.6 0.0 6.5 7.0 0.0 2.7 2 0 0 2 2 2 0 ABC transporter NTPase_1 PF03266.10 EEQ73804.1 - 0.031 13.9 0.0 0.41 10.3 0.0 2.3 2 0 0 2 2 2 0 NTPase KaiC PF06745.8 EEQ73804.1 - 0.038 13.0 0.1 4.6 6.2 0.0 2.3 2 0 0 2 2 2 0 KaiC TIP49 PF06068.8 EEQ73804.1 - 0.059 12.0 0.0 1.5 7.4 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus Viral_helicase1 PF01443.13 EEQ73804.1 - 0.059 12.8 0.0 0.55 9.6 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Cytidylate_kin2 PF13189.1 EEQ73804.1 - 0.061 13.2 0.0 3 7.6 0.0 2.8 3 0 0 3 3 3 0 Cytidylate kinase-like family Mg_chelatase PF01078.16 EEQ73804.1 - 0.064 12.4 0.1 0.84 8.7 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI cobW PF02492.14 EEQ73804.1 - 0.1 12.0 0.5 4.1 6.8 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SKI PF01202.17 EEQ73804.1 - 0.19 11.5 0.0 4.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase PduV-EutP PF10662.4 EEQ73804.1 - 0.27 10.7 0.1 3.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation HNH_2 PF13391.1 EEQ73805.1 - 0.00047 19.8 0.0 0.00088 19.0 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease DUF3209 PF11483.3 EEQ73805.1 - 0.066 13.5 2.5 0.17 12.2 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) DAP3 PF10236.4 EEQ73806.1 - 8.3e-103 343.5 0.0 1.1e-102 343.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 RRS1 PF04939.7 EEQ73807.1 - 1.4e-58 197.0 0.1 1.7e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DUF1180 PF06679.7 EEQ73807.1 - 3.8 7.3 5.5 99 2.7 3.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) RhoGAP PF00620.22 EEQ73808.1 - 4.4e-29 101.0 0.0 8.1e-29 100.1 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Mucin PF01456.12 EEQ73808.1 - 0.0043 16.8 12.7 0.012 15.3 8.8 1.7 1 0 0 1 1 1 1 Mucin-like glycoprotein Prenyltrans PF00432.16 EEQ73810.1 - 3.3e-57 189.6 8.7 2e-11 43.2 0.0 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EEQ73810.1 - 5.6e-35 120.1 0.0 1.6e-12 47.8 0.0 3.7 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EEQ73810.1 - 1e-09 38.3 0.0 0.0022 17.9 0.0 3.2 1 1 2 3 3 3 2 Prenyltransferase-like Ecl1 PF12855.2 EEQ73813.1 - 9.9e-15 53.5 1.2 9.9e-15 53.5 0.8 2.1 2 0 0 2 2 2 1 Life-span regulatory factor zf-MYND PF01753.13 EEQ73813.1 - 0.0019 18.0 0.2 0.0063 16.3 0.1 1.9 1 0 0 1 1 1 1 MYND finger DUF581 PF04570.9 EEQ73813.1 - 0.0038 16.4 0.8 0.0081 15.4 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF581) DUF2256 PF10013.4 EEQ73813.1 - 1.5 8.6 6.3 0.7 9.7 1.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) YL1 PF05764.8 EEQ73814.1 - 1.1e-59 201.9 25.0 1.1e-59 201.9 17.3 3.0 3 0 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 EEQ73814.1 - 2.4e-11 42.9 0.1 3.8e-11 42.3 0.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain PUF PF00806.14 EEQ73816.1 - 2e-29 99.3 0.0 1.1e-05 24.6 0.0 6.2 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EEQ73816.1 - 2.2e-09 36.8 0.0 5.6e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ73816.1 - 1.8e-05 24.4 0.0 4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ73816.1 - 3.9e-05 23.5 0.0 9.2e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.9 EEQ73816.1 - 2.9 7.5 7.7 2.1 7.9 0.8 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Herpes_UL45 PF05473.7 EEQ73817.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 UL45 protein CAP59_mtransfer PF11735.3 EEQ73818.1 - 1.4e-80 269.9 0.0 2e-80 269.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF1349 PF07081.6 EEQ73819.1 - 1.5e-25 89.6 0.0 2e-25 89.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) MFS_1 PF07690.11 EEQ73820.1 - 4.2e-18 65.1 41.8 8.8e-17 60.8 29.0 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ73820.1 - 1.2e-05 23.7 20.4 1.8e-05 23.1 14.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF872 PF05915.7 EEQ73820.1 - 0.033 14.0 1.0 0.15 11.9 0.0 2.6 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) SK_channel PF03530.9 EEQ73820.1 - 9.6 6.0 8.0 2.2 8.1 1.1 2.9 2 1 0 2 2 2 0 Calcium-activated SK potassium channel p450 PF00067.17 EEQ73821.1 - 1e-47 162.7 0.0 1.3e-47 162.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ras PF00071.17 EEQ73823.1 - 1.3e-52 177.4 0.0 1.5e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ73823.1 - 4.7e-16 59.3 0.0 8.8e-16 58.4 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EEQ73823.1 - 1.1e-06 27.9 0.0 1.5e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Arginase PF00491.16 EEQ73824.1 - 1.2e-89 300.3 0.0 1.4e-89 300.1 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EEQ73824.1 - 0.024 14.8 0.1 0.042 14.0 0.1 1.4 1 0 0 1 1 1 0 UPF0489 domain DUF1993 PF09351.5 EEQ73825.1 - 4.3e-52 176.2 0.0 4.9e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) ketoacyl-synt PF00109.21 EEQ73826.1 - 1.1e-57 195.4 1.0 1.9e-57 194.6 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EEQ73826.1 - 7.7e-31 106.4 0.5 1.6e-30 105.3 0.2 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EEQ73826.1 - 2.3e-05 23.5 0.2 4.3e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EEQ73826.1 - 0.057 13.0 1.6 1.5 8.5 0.0 3.2 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_C PF02803.13 EEQ73826.1 - 0.09 12.2 1.4 2.4 7.6 0.1 3.1 3 0 0 3 3 3 0 Thiolase, C-terminal domain SCA7 PF08313.7 EEQ73827.1 - 7.8e-34 115.1 0.6 2.2e-33 113.6 0.4 1.7 1 0 0 1 1 1 1 SCA7, zinc-binding domain DUF3505 PF12013.3 EEQ73827.1 - 0.4 10.9 3.5 0.23 11.6 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) mRNA_cap_enzyme PF01331.14 EEQ73828.1 - 4e-50 170.1 0.3 5.6e-50 169.7 0.2 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EEQ73828.1 - 4.7e-22 78.2 0.3 3.3e-21 75.5 0.1 2.2 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EEQ73828.1 - 6.1e-09 35.5 0.5 3.4e-07 29.8 0.3 2.6 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DUF682 PF05081.7 EEQ73828.1 - 0.5 9.8 3.3 3.8 7.0 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF682) DNA_ligase_A_M PF01068.16 EEQ73829.1 - 1.3e-50 171.5 1.1 9.3e-49 165.5 0.8 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EEQ73829.1 - 8.3e-48 162.5 0.0 1.5e-47 161.6 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EEQ73829.1 - 9e-28 96.5 0.2 3.4e-27 94.6 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region CFEM PF05730.6 EEQ73830.1 - 2.4e-12 46.5 5.4 3.5e-12 45.9 3.8 1.3 1 0 0 1 1 1 1 CFEM domain Toxin_31 PF08119.6 EEQ73830.1 - 0.59 9.7 4.0 1.2 8.7 2.8 1.5 1 0 0 1 1 1 0 Scorpion acidic alpha-KTx toxin family NPP PF08384.5 EEQ73830.1 - 2.2 7.9 11.8 3 7.5 0.0 3.3 3 0 0 3 3 3 0 Pro-opiomelanocortin, N-terminal region AAA_22 PF13401.1 EEQ73831.1 - 3.7e-08 33.5 4.0 3.1e-05 24.1 0.0 3.8 3 1 1 4 4 4 2 AAA domain NACHT PF05729.7 EEQ73831.1 - 2.4e-07 30.5 0.1 6.3e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EEQ73831.1 - 0.00018 21.5 2.7 0.006 16.5 0.0 3.9 3 1 1 4 4 4 1 AAA ATPase domain Arch_ATPase PF01637.13 EEQ73831.1 - 0.0041 16.8 1.8 0.17 11.5 0.0 3.2 3 0 0 3 3 3 1 Archaeal ATPase AAA_30 PF13604.1 EEQ73831.1 - 0.01 15.4 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EEQ73831.1 - 0.021 14.3 0.0 0.049 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EEQ73831.1 - 0.038 14.2 1.9 0.3 11.3 0.0 2.8 2 1 0 2 2 2 0 ABC transporter RNA_helicase PF00910.17 EEQ73831.1 - 0.076 13.1 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 EEQ73831.1 - 0.18 11.1 1.4 1.3 8.4 0.0 2.9 3 1 0 3 3 3 0 AAA-like domain AAA_17 PF13207.1 EEQ73831.1 - 0.26 12.1 1.4 1.6 9.5 0.0 3.1 4 1 0 4 4 4 0 AAA domain Cu_amine_oxid PF01179.15 EEQ73832.1 - 6.6e-93 311.6 0.0 8.8e-93 311.2 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 EEQ73832.1 - 9.8e-06 25.3 0.0 2.6e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 EEQ73832.1 - 0.0022 18.0 0.0 0.0051 16.8 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain HEAT_2 PF13646.1 EEQ73833.1 - 3.6e-06 27.1 1.7 0.061 13.6 0.0 4.2 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.17 EEQ73833.1 - 0.0075 16.2 0.6 32 4.9 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.18 EEQ73833.1 - 0.065 13.0 0.1 23 4.9 0.0 3.1 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EEQ73833.1 - 0.52 10.8 5.7 12 6.5 0.1 3.8 3 1 1 4 4 4 0 HEAT-like repeat eIF-5_eIF-2B PF01873.12 EEQ73834.1 - 2.8e-38 130.4 0.0 4.5e-38 129.7 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EEQ73834.1 - 8.5e-25 86.5 0.6 2.2e-24 85.2 0.4 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon HK PF02110.10 EEQ73835.1 - 2.8e-72 242.8 0.0 5.4e-72 241.9 0.0 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EEQ73835.1 - 2.1e-57 193.1 0.7 3.5e-57 192.4 0.5 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Carb_kinase PF01256.12 EEQ73835.1 - 0.009 15.3 0.0 0.026 13.8 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate kinase Pertussis_S1 PF02917.9 EEQ73835.1 - 0.092 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 Isochorismatase PF00857.15 EEQ73836.1 - 5.6e-23 81.7 0.2 8.9e-23 81.1 0.1 1.3 1 0 0 1 1 1 1 Isochorismatase family Voltage_CLC PF00654.15 EEQ73837.1 - 7.3e-83 278.5 22.6 7.5e-58 196.2 6.3 3.1 3 0 0 3 3 3 2 Voltage gated chloride channel DUF3848 PF12959.2 EEQ73837.1 - 0.23 11.4 0.0 0.49 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) Lipase_GDSL_2 PF13472.1 EEQ73838.1 - 1.4e-23 83.9 0.0 2e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EEQ73838.1 - 8.3e-15 55.2 0.0 2.6e-14 53.5 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EEQ73838.1 - 6.3e-05 22.7 0.0 0.00061 19.5 0.0 2.4 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family DHFR_1 PF00186.14 EEQ73840.1 - 3.7e-18 65.6 0.1 3.9e-09 36.3 0.0 3.9 4 0 0 4 4 4 3 Dihydrofolate reductase BAF1_ABF1 PF04684.8 EEQ73840.1 - 0.011 14.5 0.2 0.025 13.4 0.3 1.5 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor RAB3GAP2_N PF14655.1 EEQ73840.1 - 0.016 14.2 0.2 0.023 13.6 0.1 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PHD_3 PF13922.1 EEQ73840.1 - 0.16 12.2 2.1 0.37 11.0 1.3 1.8 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx Chlamy_scaf PF09675.5 EEQ73840.1 - 0.56 10.2 0.0 0.56 10.2 0.0 1.9 2 0 0 2 2 2 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) TSA PF03249.8 EEQ73840.1 - 8.3 4.8 9.6 12 4.3 6.7 1.1 1 0 0 1 1 1 0 Type specific antigen Med22 PF06179.7 EEQ73841.1 - 5.8e-22 77.7 0.9 6.9e-22 77.5 0.6 1.0 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DEPP PF15343.1 EEQ73841.1 - 0.059 12.9 0.1 0.065 12.8 0.0 1.3 1 1 0 1 1 1 0 Decidual protein induced by progesterone family GPW_gp25 PF04965.9 EEQ73841.1 - 0.11 11.9 0.8 0.22 11.0 0.1 1.7 2 0 0 2 2 2 0 Gene 25-like lysozyme Cwf_Cwc_15 PF04889.7 EEQ73842.1 - 6.7e-88 294.5 16.0 7.5e-88 294.3 11.1 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.4 EEQ73842.1 - 9.9e-05 21.9 9.3 0.00014 21.4 6.4 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein PPP4R2 PF09184.6 EEQ73842.1 - 0.2 11.1 18.6 0.27 10.7 12.9 1.1 1 0 0 1 1 1 0 PPP4R2 FAM91_C PF14648.1 EEQ73842.1 - 0.22 10.3 0.8 0.26 10.0 0.5 1.1 1 0 0 1 1 1 0 FAM91 C-terminus PA26 PF04636.8 EEQ73842.1 - 0.56 8.8 3.6 0.6 8.7 2.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CDC27 PF09507.5 EEQ73842.1 - 0.59 9.2 17.1 0.74 8.9 11.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.9 EEQ73842.1 - 1.7 6.5 16.4 2.1 6.2 11.4 1.1 1 0 0 1 1 1 0 CDC45-like protein eIF-3c_N PF05470.7 EEQ73842.1 - 2 6.3 12.3 2.7 5.9 8.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus APG6 PF04111.7 EEQ73842.1 - 2.1 7.3 9.4 2.8 6.8 6.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1510 PF07423.6 EEQ73842.1 - 2.7 7.3 15.6 3.5 6.9 10.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) HNF-1_N PF04814.8 EEQ73842.1 - 2.9 7.9 8.8 5.5 7.0 5.7 1.8 1 1 1 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus RR_TM4-6 PF06459.7 EEQ73842.1 - 4.3 7.1 11.8 6.3 6.6 8.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TAF8_C PF10406.4 EEQ73842.1 - 5.3 7.1 8.2 27 4.9 0.1 3.5 3 1 0 3 3 3 0 Transcription factor TFIID complex subunit 8 C-term GET2 PF08690.5 EEQ73842.1 - 8.6 5.5 7.1 15 4.6 4.9 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 RNase_PH PF01138.16 EEQ73843.1 - 5.8e-21 75.1 0.0 1.1e-20 74.2 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EEQ73843.1 - 6.3e-05 22.8 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 HAD PF12710.2 EEQ73844.1 - 1.7e-18 67.4 0.1 3.5e-18 66.4 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EEQ73844.1 - 6e-16 58.1 0.0 1e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EEQ73844.1 - 2.7e-14 54.1 0.0 1.2e-13 52.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ73844.1 - 1.3e-12 47.5 0.0 3.8e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEQ73844.1 - 0.0034 17.0 0.3 0.014 14.9 0.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EEQ73844.1 - 0.021 15.0 0.1 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DNA_pol_lambd_f PF10391.4 EEQ73845.1 - 1.8e-19 69.0 0.7 3.7e-19 68.0 0.5 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 EEQ73845.1 - 5.1e-19 67.7 0.0 2.1e-18 65.7 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 EEQ73845.1 - 2.8e-17 62.7 0.1 7.4e-17 61.4 0.1 1.7 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 EEQ73845.1 - 4.2e-10 39.6 0.1 1.3e-09 38.0 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 EEQ73845.1 - 0.083 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif NicO PF03824.11 EEQ73846.1 - 9.7e-55 185.8 17.0 9.3e-53 179.3 4.2 2.3 2 0 0 2 2 2 2 High-affinity nickel-transport protein Utp12 PF04003.7 EEQ73847.1 - 0.051 13.4 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Dip2/Utp12 Family Peptidase_M14 PF00246.19 EEQ73849.1 - 3.3e-69 233.5 0.0 4.2e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Sec7 PF01369.15 EEQ73851.1 - 2.2e-38 131.8 0.0 3.6e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EEQ73851.1 - 4.2e-07 30.1 0.1 8.3e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EEQ73851.1 - 9.3e-06 25.7 0.0 2.4e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 PH domain SET PF00856.23 EEQ73854.1 - 2.4e-11 44.1 0.1 2.4e-11 44.1 0.1 2.7 2 2 0 2 2 2 1 SET domain DUF1367 PF07105.6 EEQ73854.1 - 0.0017 17.7 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1367) Defensin_2 PF01097.13 EEQ73855.1 - 1e-07 31.5 13.9 1.3e-07 31.1 9.6 1.2 1 0 0 1 1 1 1 Arthropod defensin Toxin_2 PF00451.14 EEQ73855.1 - 0.92 9.6 9.4 1.4 9.1 6.5 1.3 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 Gamma-thionin PF00304.15 EEQ73855.1 - 1.2 9.2 8.2 1.6 8.7 5.7 1.2 1 0 0 1 1 1 0 Gamma-thionin family YrzO PF14142.1 EEQ73856.1 - 0.09 12.4 0.0 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 YrzO-like protein DUF3255 PF11631.3 EEQ73856.1 - 0.12 12.0 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3255) Fringe PF02434.11 EEQ73857.1 - 1.6e-06 27.4 0.5 2.6e-05 23.5 0.4 2.3 1 1 0 1 1 1 1 Fringe-like PAN_1 PF00024.21 EEQ73857.1 - 0.00022 20.9 0.5 0.00051 19.7 0.4 1.6 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.6 EEQ73857.1 - 0.0026 17.5 0.5 0.0053 16.5 0.4 1.4 1 0 0 1 1 1 1 PAN-like domain PAN_3 PF08277.7 EEQ73857.1 - 0.0067 16.0 0.2 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 PAN-like domain Glyco_tranf_2_3 PF13641.1 EEQ73857.1 - 0.021 14.6 0.1 3.2 7.4 0.0 2.5 2 1 1 3 3 3 0 Glycosyltransferase like family 2 zf-C3HC4_2 PF13923.1 EEQ73858.1 - 2.7e-07 30.4 13.1 0.00028 20.8 3.8 3.0 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ73858.1 - 0.00017 21.3 11.8 0.0039 16.9 3.5 2.6 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.1 EEQ73858.1 - 0.00029 20.5 13.5 0.00043 19.9 4.3 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EEQ73858.1 - 0.00054 19.5 2.5 0.00054 19.5 1.8 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ73858.1 - 0.00095 18.7 5.7 0.00095 18.7 3.9 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EEQ73858.1 - 0.0013 18.0 5.3 0.0013 18.0 3.7 3.1 2 2 1 3 3 3 1 Rtf2 RING-finger FYVE PF01363.16 EEQ73858.1 - 0.0019 18.0 11.3 0.046 13.6 3.4 3.6 2 1 1 3 3 3 1 FYVE zinc finger zf-RING_UBOX PF13445.1 EEQ73858.1 - 0.0038 16.9 4.4 0.0038 16.9 3.0 2.1 2 0 0 2 2 2 1 RING-type zinc-finger RIG-I_C-RD PF11648.3 EEQ73858.1 - 0.016 15.1 3.0 0.016 15.1 2.1 2.0 2 0 0 2 2 2 0 C-terminal domain of RIG-I Atg14 PF10186.4 EEQ73858.1 - 0.33 9.8 4.4 0.61 8.9 3.0 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Prok-RING_4 PF14447.1 EEQ73858.1 - 0.51 9.9 4.2 2.6 7.6 2.9 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 UPF1_Zn_bind PF09416.5 EEQ73858.1 - 1.5 8.3 9.8 6.2 6.3 0.9 2.5 2 1 0 2 2 2 0 RNA helicase (UPF2 interacting domain) DUF2180 PF09947.4 EEQ73858.1 - 3.7 7.3 7.1 0.46 10.2 0.9 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) zf-C3HC4_4 PF15227.1 EEQ73858.1 - 5.7 6.9 14.3 0.33 10.8 2.6 3.2 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Endonuclease_NS PF01223.18 EEQ73859.1 - 6.7e-59 198.9 0.0 9.7e-59 198.4 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease DUF3439 PF11921.3 EEQ73859.1 - 0.77 9.5 9.1 1.5 8.6 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Zip PF02535.17 EEQ73860.1 - 3.3e-14 52.6 26.5 2.6e-13 49.6 18.4 2.3 1 1 0 1 1 1 1 ZIP Zinc transporter DUF2040 PF09745.4 EEQ73861.1 - 6.5e-41 139.1 13.2 6.5e-41 139.1 9.1 4.4 3 2 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) Sedlin_N PF04628.8 EEQ73862.1 - 3.8e-38 130.3 0.0 4.5e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EEQ73862.1 - 0.021 14.5 0.0 0.047 13.3 0.0 1.5 2 0 0 2 2 2 0 Sybindin-like family Isochorismatase PF00857.15 EEQ73863.1 - 2.7e-41 141.3 0.0 5e-41 140.5 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family FAR1 PF03101.10 EEQ73863.1 - 1e-06 29.1 0.0 2.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain PriCT_2 PF08707.6 EEQ73863.1 - 0.053 13.3 0.0 0.095 12.5 0.0 1.3 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) AFT PF08731.6 EEQ73863.1 - 0.061 13.5 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Transcription factor AFT NUDE_C PF04880.8 EEQ73864.1 - 2e-23 83.5 7.6 2e-23 83.5 5.2 3.9 3 2 1 4 4 2 1 NUDE protein, C-terminal conserved region DUF904 PF06005.7 EEQ73864.1 - 0.0014 18.8 8.9 0.0014 18.8 6.1 4.0 3 1 1 4 4 4 1 Protein of unknown function (DUF904) IncA PF04156.9 EEQ73864.1 - 0.01 15.4 13.1 0.01 15.4 9.1 2.6 2 1 0 3 3 3 0 IncA protein ATG16 PF08614.6 EEQ73864.1 - 0.21 11.4 26.4 0.14 11.9 11.1 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Myosin_tail_1 PF01576.14 EEQ73864.1 - 0.38 8.4 28.7 0.59 7.7 19.9 1.2 1 0 0 1 1 1 0 Myosin tail DUF4250 PF14056.1 EEQ73864.1 - 0.51 10.1 3.7 38 4.0 0.1 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4250) WEMBL PF05701.6 EEQ73864.1 - 0.58 8.5 28.3 0.82 8.0 19.6 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light FliD_N PF02465.13 EEQ73864.1 - 1 9.7 6.3 11 6.5 0.2 3.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus ERM PF00769.14 EEQ73864.1 - 1.1 8.7 25.0 0.09 12.2 6.5 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CCDC144C PF14915.1 EEQ73864.1 - 1.8 7.4 25.1 0.17 10.7 9.2 2.8 2 1 0 3 3 3 0 CCDC144C protein coiled-coil region Tho2 PF11262.3 EEQ73864.1 - 7.7 5.4 10.6 1.6 7.7 0.3 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 APH PF01636.18 EEQ73867.1 - 1.8e-07 31.1 0.0 3e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family ACC_central PF08326.7 EEQ73868.1 - 5.2e-264 877.7 0.0 7.3e-264 877.2 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EEQ73868.1 - 4.3e-183 609.1 0.0 6.7e-183 608.5 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EEQ73868.1 - 2.4e-52 177.2 0.0 4.5e-52 176.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EEQ73868.1 - 9.1e-24 83.6 0.0 1.7e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EEQ73868.1 - 7.2e-23 80.6 0.0 1.2e-19 70.2 0.0 3.8 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EEQ73868.1 - 2.4e-16 59.1 0.1 7e-16 57.6 0.0 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EEQ73868.1 - 7.9e-10 38.7 0.0 2.1e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EEQ73868.1 - 3.3e-08 32.6 0.0 4.3e-06 25.7 0.0 3.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EEQ73868.1 - 5.8e-05 22.5 0.0 0.00015 21.1 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EEQ73868.1 - 0.00016 21.5 0.0 0.0005 19.9 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 EEQ73868.1 - 0.0058 16.0 0.1 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HeLo PF14479.1 EEQ73869.1 - 0.01 15.5 1.3 0.21 11.3 0.8 2.4 1 1 1 2 2 2 0 Prion-inhibition and propagation Peptidase_S64 PF08192.6 EEQ73869.1 - 3.3 5.9 8.4 0.84 7.8 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S64 RINGv PF12906.2 EEQ73870.1 - 5.9e-16 58.2 9.6 1.1e-15 57.4 6.7 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EEQ73870.1 - 0.016 14.9 7.6 0.035 13.9 5.3 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 EEQ73870.1 - 0.096 12.3 4.9 0.18 11.5 3.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEQ73870.1 - 0.12 12.1 2.3 0.28 11.0 1.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1510 PF07423.6 EEQ73870.1 - 0.17 11.2 1.8 0.33 10.3 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) zf-RING_4 PF14570.1 EEQ73870.1 - 2 8.0 7.4 3.6 7.2 5.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Peptidase_U35_2 PF14550.1 EEQ73871.1 - 0.021 14.4 5.1 12 5.5 0.3 4.0 4 0 0 4 4 4 0 Putative phage protease XkdF Apolipoprotein PF01442.13 EEQ73871.1 - 0.17 11.3 1.2 3.6 7.0 0.2 3.2 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Phasin_2 PF09361.5 EEQ73871.1 - 6.1 6.9 11.2 0.41 10.6 0.1 4.0 4 0 0 4 4 4 0 Phasin protein DUF788 PF05620.6 EEQ73872.1 - 1e-41 142.6 0.0 1.5e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Sigma70_ner PF04546.8 EEQ73872.1 - 0.068 12.7 0.2 0.084 12.4 0.1 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region TPR_1 PF00515.23 EEQ73873.1 - 9.1e-40 132.6 19.6 1.5e-07 30.7 0.1 9.7 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ73873.1 - 2.3e-39 132.8 27.8 7.2e-14 51.1 0.7 8.1 5 1 4 9 9 9 8 TPR repeat TPR_2 PF07719.12 EEQ73873.1 - 2e-36 120.9 17.6 2.4e-05 23.9 0.0 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat Apc3 PF12895.2 EEQ73873.1 - 1.8e-31 108.1 22.1 2.8e-23 81.8 0.1 5.0 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EEQ73873.1 - 1.6e-24 85.6 17.4 5.4e-05 23.0 0.0 7.1 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ73873.1 - 3e-24 82.9 6.8 0.0043 16.7 0.0 9.4 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ73873.1 - 3.8e-24 84.7 16.1 4.6e-07 30.3 0.0 8.3 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ73873.1 - 1.5e-18 66.8 14.0 1.2e-05 25.4 0.7 7.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ73873.1 - 1.8e-17 62.2 6.7 0.11 13.1 0.2 9.9 5 2 4 10 10 10 3 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ73873.1 - 3.8e-13 48.5 12.7 1.9 8.8 0.0 9.7 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ73873.1 - 8.1e-12 44.0 7.7 0.053 13.3 0.0 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ73873.1 - 2.6e-07 30.6 11.9 2.6 8.6 0.0 8.3 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ73873.1 - 0.017 14.9 7.6 29 4.6 0.0 5.7 4 1 3 7 7 7 0 Tetratricopeptide repeat DUF627 PF04781.7 EEQ73873.1 - 0.017 14.7 0.0 0.66 9.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF627) TPR_15 PF13429.1 EEQ73873.1 - 0.019 14.0 6.1 1.6 7.7 0.1 4.0 2 2 1 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 EEQ73873.1 - 0.082 12.7 6.0 0.19 11.6 0.1 4.1 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain APP_E2 PF12925.2 EEQ73873.1 - 0.097 12.2 0.5 0.28 10.7 0.3 1.8 1 1 0 1 1 1 0 E2 domain of amyloid precursor protein TPR_21 PF09976.4 EEQ73873.1 - 0.35 10.8 4.1 7.4 6.5 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Acyltransferase PF01553.16 EEQ73874.1 - 3.1e-32 110.7 0.0 5.4e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase ACPS PF01648.15 EEQ73875.1 - 4.2e-09 36.2 0.0 8.9e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily SNO PF01174.14 EEQ73876.1 - 6.7e-52 175.8 0.0 1.3e-40 139.0 0.0 2.2 1 1 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EEQ73876.1 - 6.5e-09 35.5 0.0 4.8e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EEQ73876.1 - 0.00015 21.2 0.0 0.00089 18.7 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DUF4066 PF13278.1 EEQ73876.1 - 0.00067 18.9 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EEQ73876.1 - 0.0038 16.6 0.0 0.006 16.0 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family RRM_1 PF00076.17 EEQ73877.1 - 2.7e-15 55.7 0.0 5.7e-15 54.6 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ73877.1 - 6.6e-12 45.2 0.0 1.1e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ73877.1 - 1.4e-08 34.4 0.0 2.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rotamase PF00639.16 EEQ73881.1 - 2.6e-22 79.3 0.0 3.7e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EEQ73881.1 - 1.6e-15 57.3 0.0 1.9e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EEQ73881.1 - 8.7e-11 41.4 2.9 1.7e-10 40.5 2.0 1.5 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 EEQ73881.1 - 2.6e-06 28.0 0.0 3.5e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain MAM PF00629.18 EEQ73881.1 - 0.085 12.6 0.0 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 MAM domain RNA_POL_M_15KD PF02150.11 EEQ73882.1 - 7.1e-11 41.6 0.8 1.4e-10 40.6 0.6 1.5 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit GFA PF04828.9 EEQ73882.1 - 0.00061 19.6 2.1 0.02 14.8 0.3 2.1 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EEQ73882.1 - 0.33 10.7 5.2 3.4 7.5 3.6 2.2 1 1 0 1 1 1 0 Double zinc ribbon Rpr2 PF04032.11 EEQ73882.1 - 0.51 10.2 3.1 1.8 8.5 1.9 1.9 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Cytochrome_C7 PF14522.1 EEQ73882.1 - 0.97 9.1 4.6 1.6 8.4 3.2 1.6 1 1 0 1 1 1 0 Cytochrome c7 TNFR_c6 PF00020.13 EEQ73882.1 - 2.7 8.1 9.7 1.6 8.8 0.9 2.9 2 1 1 3 3 3 0 TNFR/NGFR cysteine-rich region Ribosomal_L14 PF00238.14 EEQ73883.1 - 4.3e-44 149.1 0.7 4.7e-44 149.0 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SET PF00856.23 EEQ73884.1 - 2e-08 34.7 3.0 4.8e-08 33.4 0.0 2.6 2 1 0 2 2 2 1 SET domain DUF2058 PF09831.4 EEQ73884.1 - 4.5 7.1 7.2 8.7 6.1 5.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DEAD PF00270.24 EEQ73886.1 - 1.3e-30 106.0 0.3 6.7e-30 103.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ73886.1 - 4.9e-17 61.5 0.0 1.4e-16 60.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ73886.1 - 0.0012 18.7 0.2 0.0031 17.3 0.1 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EEQ73886.1 - 0.0027 16.5 0.0 0.0046 15.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Anillin PF08174.6 EEQ73887.1 - 7.1e-32 110.3 0.3 2.7e-31 108.5 0.2 2.1 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 EEQ73887.1 - 8.9e-09 35.4 0.0 2.7e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EEQ73887.1 - 0.015 15.5 0.0 0.037 14.2 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PseudoU_synth_1 PF01416.15 EEQ73888.1 - 3.8e-18 65.8 0.0 2.5e-09 37.4 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase TFIIE_alpha PF02002.12 EEQ73889.1 - 6.6e-20 70.5 0.1 8.9e-19 66.9 0.0 2.4 2 0 0 2 2 2 1 TFIIE alpha subunit Zn-ribbon_8 PF09723.5 EEQ73889.1 - 0.011 15.6 1.0 0.021 14.7 0.1 1.9 2 0 0 2 2 2 0 Zinc ribbon domain HTH_Crp_2 PF13545.1 EEQ73889.1 - 0.083 12.6 0.1 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Dehydratase_hem PF13816.1 EEQ73890.1 - 1.6e-116 388.6 0.0 1.9e-116 388.4 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.1 EEQ73890.1 - 0.00011 22.3 0.0 0.49 10.4 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) DUF1469 PF07332.6 EEQ73891.1 - 0.37 10.5 3.4 0.22 11.2 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF3517 PF12030.3 EEQ73892.1 - 2.4e-165 549.0 0.0 4.3e-165 548.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.24 EEQ73892.1 - 4.1e-47 160.5 0.0 7.4e-47 159.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEQ73892.1 - 7.4e-17 61.7 0.1 2.5e-16 59.9 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Hexapep PF00132.19 EEQ73893.1 - 7.1e-17 60.0 11.8 1.1e-11 43.7 3.1 3.2 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EEQ73893.1 - 3.6e-14 52.0 11.6 1.5e-10 40.4 2.0 2.9 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 EEQ73893.1 - 1.4e-13 50.6 0.0 2.3e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase ICMT PF04140.9 EEQ73895.1 - 2.3e-29 101.4 0.1 5e-29 100.3 0.1 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EEQ73895.1 - 7e-15 55.0 1.1 7e-15 55.0 0.7 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 EEQ73895.1 - 0.00013 21.3 0.2 0.00018 20.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.6 EEQ73895.1 - 0.0014 18.0 2.9 0.0042 16.4 2.0 1.8 1 1 0 1 1 1 1 NnrU protein Tmemb_170 PF10190.4 EEQ73898.1 - 0.00019 21.4 6.9 0.00025 21.0 4.8 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 O-ag_pol_Wzy PF14296.1 EEQ73898.1 - 0.18 10.3 10.6 1.2 7.6 7.0 1.8 1 1 1 2 2 2 0 O-antigen polysaccharide polymerase Wzy WD40 PF00400.27 EEQ73899.1 - 8.7e-48 158.5 32.9 2.5e-08 33.4 1.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EEQ73899.1 - 0.0013 18.4 0.4 0.081 12.6 0.1 2.7 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Bacteroid_pep PF14406.1 EEQ73899.1 - 0.094 12.8 0.0 0.29 11.3 0.0 1.9 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes PAT1 PF09770.4 EEQ73899.1 - 5.3 5.1 17.0 7.2 4.7 11.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MBOAT PF03062.14 EEQ73900.1 - 6.2e-20 71.5 15.5 1.3e-19 70.5 10.7 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EEQ73900.1 - 0.00088 19.3 2.8 0.0028 17.6 1.9 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MFS_1 PF07690.11 EEQ73903.1 - 1.2e-38 132.7 55.0 1.2e-38 132.7 38.1 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ73903.1 - 1.1e-13 50.2 25.8 1.5e-13 49.8 17.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEQ73903.1 - 1e-12 47.3 17.8 1e-12 47.3 12.3 2.6 1 1 2 3 3 3 1 Sugar (and other) transporter OATP PF03137.15 EEQ73903.1 - 0.023 12.7 6.6 0.19 9.7 0.5 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ADH_zinc_N_2 PF13602.1 EEQ73904.1 - 0.0016 19.3 0.0 0.0035 18.2 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Zn_clus PF00172.13 EEQ73905.1 - 0.00014 21.6 7.4 0.00024 20.9 5.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.18 EEQ73907.1 - 7.6e-14 52.0 0.0 1.3e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ73907.1 - 4.1e-05 23.2 0.0 7.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase MAPEG PF01124.13 EEQ73908.1 - 2.2e-25 88.7 1.5 2.6e-25 88.4 1.0 1.0 1 0 0 1 1 1 1 MAPEG family OMPdecase PF00215.19 EEQ73910.1 - 1e-72 244.1 0.0 2e-72 243.2 0.0 1.4 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Ribosomal_60s PF00428.14 EEQ73910.1 - 0.0013 19.1 4.5 0.0013 19.1 3.1 1.7 2 0 0 2 2 2 1 60s Acidic ribosomal protein Nucleoplasmin PF03066.10 EEQ73910.1 - 0.0074 15.8 0.7 0.011 15.2 0.5 1.3 1 0 0 1 1 1 1 Nucleoplasmin BSP_II PF05432.6 EEQ73910.1 - 0.046 12.9 9.9 0.067 12.4 6.9 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Myc_N PF01056.13 EEQ73910.1 - 0.27 10.3 7.0 0.11 11.6 3.1 1.5 2 0 0 2 2 2 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 EEQ73910.1 - 0.31 11.3 6.8 0.55 10.4 4.7 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Daxx PF03344.10 EEQ73910.1 - 5.2 5.4 5.5 7.1 4.9 3.8 1.1 1 0 0 1 1 1 0 Daxx Family Pkinase PF00069.20 EEQ73915.1 - 0.00017 20.8 0.0 0.0032 16.6 0.0 2.6 3 0 0 3 3 3 1 Protein kinase domain S4 PF01479.20 EEQ73916.1 - 1.1e-11 43.9 0.1 2e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 EEQ73916.1 - 8.8e-07 29.2 1.1 1.3e-06 28.7 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Occludin_ELL PF07303.8 EEQ73916.1 - 0.047 14.4 0.4 0.093 13.4 0.0 1.7 2 0 0 2 2 2 0 Occludin homology domain DIPSY PF11763.3 EEQ73918.1 - 0.034 13.9 0.0 0.043 13.5 0.0 1.1 1 0 0 1 1 1 0 Cell-wall adhesin ligand-binding C-terminal DnaJ PF00226.26 EEQ73921.1 - 6.2e-25 86.7 1.0 1.2e-24 85.7 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EEQ73921.1 - 9.4e-16 57.6 16.4 1.6e-15 56.9 11.4 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 EEQ73921.1 - 9.1e-14 51.1 0.0 2.4e-12 46.5 0.0 2.3 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 EEQ73921.1 - 0.023 14.3 9.6 0.17 11.5 1.3 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Ogr_Delta PF04606.7 EEQ73921.1 - 0.34 10.6 4.2 0.81 9.3 0.1 2.9 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger DZR PF12773.2 EEQ73921.1 - 2.2 8.1 14.1 9 6.2 2.8 2.2 1 1 1 2 2 2 0 Double zinc ribbon Lar_restr_allev PF14354.1 EEQ73921.1 - 2.9 8.2 9.1 8.3 6.7 0.2 2.8 1 1 1 2 2 2 0 Restriction alleviation protein Lar DUF4449 PF14613.1 EEQ73922.1 - 0.0037 17.2 0.2 0.0037 17.2 0.2 2.8 3 1 0 3 3 3 1 Protein of unknown function (DUF4449) Malic_M PF03949.10 EEQ73923.1 - 1.1e-86 290.6 0.0 1.4e-86 290.2 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EEQ73923.1 - 2.9e-63 212.7 0.0 4.5e-63 212.1 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Fucose_iso_N1 PF07881.7 EEQ73923.1 - 0.15 11.6 0.0 3.7 7.0 0.0 2.2 2 0 0 2 2 2 0 L-fucose isomerase, first N-terminal domain THOC7 PF05615.8 EEQ73924.1 - 1.4e-43 148.5 7.6 1.4e-43 148.5 5.3 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 zf-C4H2 PF10146.4 EEQ73924.1 - 0.00051 20.1 13.5 0.016 15.1 4.5 2.4 1 1 2 3 3 3 2 Zinc finger-containing protein CCDC92 PF14916.1 EEQ73924.1 - 0.0077 15.7 1.0 0.023 14.3 0.7 1.7 1 0 0 1 1 1 1 Coiled-coil domain of unknown function Slu7 PF11708.3 EEQ73924.1 - 0.074 12.7 7.0 0.11 12.2 4.9 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor DUF4600 PF15372.1 EEQ73924.1 - 0.47 10.6 12.2 0.87 9.8 8.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) FUSC PF04632.7 EEQ73924.1 - 1.7 7.0 4.1 2.1 6.6 2.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CDC37_N PF03234.9 EEQ73924.1 - 2.5 8.4 8.8 2.6 8.3 5.4 1.6 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF1843 PF08898.5 EEQ73924.1 - 3.4 7.7 6.8 0.62 10.1 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DUF342 PF03961.8 EEQ73924.1 - 7.7 4.8 9.3 16 3.7 6.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Ank_2 PF12796.2 EEQ73925.1 - 4.3e-14 52.6 0.0 1.4e-05 25.3 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ73925.1 - 9.1e-14 50.4 0.2 0.00049 19.7 0.0 5.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 EEQ73925.1 - 4.2e-11 42.7 0.0 0.00022 21.3 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ73925.1 - 7.1e-10 38.1 0.0 0.19 12.0 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EEQ73925.1 - 1e-08 35.4 0.0 0.011 16.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) TBCA PF02970.11 EEQ73926.1 - 2.6e-23 81.9 6.0 3.3e-23 81.5 4.2 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A MinE PF03776.9 EEQ73926.1 - 0.015 14.7 0.2 0.029 13.8 0.1 1.5 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE TAP42 PF04177.7 EEQ73926.1 - 0.026 13.4 2.9 0.029 13.3 2.0 1.1 1 0 0 1 1 1 0 TAP42-like family PspA_IM30 PF04012.7 EEQ73926.1 - 0.026 13.8 8.6 0.18 11.1 1.3 2.1 2 0 0 2 2 2 0 PspA/IM30 family DUF1202 PF06717.6 EEQ73926.1 - 0.066 12.4 2.1 0.078 12.2 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) BRO1 PF03097.13 EEQ73926.1 - 0.068 11.9 0.1 0.077 11.7 0.1 1.2 1 0 0 1 1 1 0 BRO1-like domain DUF2570 PF10828.3 EEQ73926.1 - 0.24 11.0 5.6 0.68 9.5 3.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) Mnd1 PF03962.10 EEQ73926.1 - 0.29 10.7 5.0 0.36 10.4 3.5 1.1 1 0 0 1 1 1 0 Mnd1 family T2SM PF04612.7 EEQ73926.1 - 0.3 10.8 2.0 0.43 10.3 0.8 1.6 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M DivIC PF04977.10 EEQ73926.1 - 0.65 9.5 5.4 4.1 6.9 0.3 2.3 2 0 0 2 2 2 0 Septum formation initiator MFS_1 PF07690.11 EEQ73927.1 - 4.6e-26 91.3 31.0 4.6e-26 91.3 21.5 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily SPC12 PF06645.8 EEQ73927.1 - 0.84 9.4 14.2 1.4 8.8 1.1 3.9 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Band_7 PF01145.20 EEQ73929.1 - 1.9e-16 60.4 0.0 1.9e-16 60.4 0.0 2.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family NS3_envE PF02723.9 EEQ73930.1 - 0.075 12.9 0.6 0.12 12.2 0.4 1.2 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E IL6 PF00489.12 EEQ73931.1 - 0.059 12.9 0.0 0.071 12.7 0.0 1.1 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family Sugar_tr PF00083.19 EEQ73932.1 - 8.9e-57 192.6 28.9 1.3e-56 192.0 20.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ73932.1 - 3.3e-07 29.3 21.9 3.3e-07 29.3 15.2 3.0 1 1 2 3 3 3 1 Major Facilitator Superfamily Elongin_A PF06881.6 EEQ73933.1 - 9.5e-24 83.8 0.4 1.8e-23 83.0 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A ubiquitin PF00240.18 EEQ73934.1 - 8.1e-25 86.0 0.0 9.1e-25 85.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EEQ73934.1 - 1.2e-16 60.0 0.0 1.3e-16 59.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EEQ73934.1 - 3.3e-05 24.0 0.0 0.00012 22.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Myb_DNA-binding PF00249.26 EEQ73936.1 - 1.4e-13 50.6 4.0 6.4e-09 35.7 0.1 2.9 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEQ73936.1 - 6.6e-09 35.7 0.7 1.1e-05 25.3 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain BCS1_N PF08740.6 EEQ73937.1 - 3e-29 101.9 0.3 9.7e-29 100.3 0.2 1.8 1 1 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EEQ73937.1 - 9.1e-21 74.4 0.1 2.3e-19 69.8 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEQ73937.1 - 0.00032 20.7 0.1 0.00082 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EEQ73937.1 - 0.0055 16.1 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEQ73937.1 - 0.0081 16.9 0.3 0.05 14.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EEQ73937.1 - 0.035 14.2 0.0 0.23 11.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 EEQ73937.1 - 0.046 12.8 0.0 0.085 11.9 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.9 EEQ73937.1 - 0.068 12.9 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EEQ73937.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF150 PF02576.12 EEQ73939.1 - 0.018 14.5 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised BCR, YhbC family COG0779 PARG_cat PF05028.9 EEQ73940.1 - 0.024 13.8 0.0 0.027 13.7 0.0 1.1 1 0 0 1 1 1 0 Poly (ADP-ribose) glycohydrolase (PARG) Pkinase PF00069.20 EEQ73941.1 - 3.7e-09 36.0 0.0 5e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EEQ73941.1 - 0.00036 19.6 0.0 0.00061 18.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ73941.1 - 0.0012 18.5 4.2 0.041 13.6 0.8 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EEQ73941.1 - 0.013 14.6 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Trypsin PF00089.21 EEQ73943.1 - 0.17 11.4 2.5 0.18 11.3 1.7 1.0 1 0 0 1 1 1 0 Trypsin N-glycanase_C PF09113.5 EEQ73943.1 - 0.2 11.3 1.7 0.26 10.9 1.2 1.2 1 0 0 1 1 1 0 Peptide-N-glycosidase F, C terminal Ribosomal_L44 PF00935.14 EEQ73944.1 - 2.8e-35 120.1 11.7 4.3e-35 119.5 8.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Vac7 PF12751.2 EEQ73945.1 - 2e-199 662.2 1.4 2e-199 662.2 1.0 1.8 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 MIP-T3 PF10243.4 EEQ73946.1 - 0.02 13.3 0.2 0.021 13.2 0.1 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 MSP1_C PF07462.6 EEQ73946.1 - 0.42 8.9 1.3 0.5 8.6 0.9 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus GP46 PF07409.7 EEQ73946.1 - 1.2 8.4 6.7 0.39 10.0 2.7 1.6 2 0 0 2 2 2 0 Phage protein GP46 DUF3824 PF12868.2 EEQ73949.1 - 6.1e-50 169.7 29.1 6.1e-50 169.7 20.2 7.7 2 1 6 8 8 8 2 Domain of unknwon function (DUF3824) DUF2613 PF11021.3 EEQ73949.1 - 0.0051 16.5 2.9 0.035 13.7 0.1 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2613) DUF4171 PF13775.1 EEQ73949.1 - 0.016 15.3 5.7 0.016 15.3 3.9 5.3 5 0 0 5 5 5 0 Domain of unknown function (DUF4171) Ribosomal_60s PF00428.14 EEQ73949.1 - 3 8.3 9.6 21 5.5 0.0 3.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein CorA PF01544.13 EEQ73950.1 - 1.6e-40 138.9 1.3 4.4e-40 137.5 0.9 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Ly49 PF08391.5 EEQ73951.1 - 2.7 8.1 0.8 13 5.9 0.5 2.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Bac_export_2 PF01312.14 EEQ73951.1 - 9.1 5.0 0.6 16 4.2 0.4 1.3 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Lipase_GDSL_2 PF13472.1 EEQ73953.1 - 3.4e-17 63.1 0.3 4.5e-17 62.7 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EEQ73953.1 - 1.9e-13 50.7 0.0 2.5e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EEQ73953.1 - 0.00019 21.2 0.0 0.0003 20.5 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family adh_short PF00106.20 EEQ73954.1 - 1.2e-23 83.8 5.5 3.3e-23 82.4 3.8 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ73954.1 - 9.8e-07 28.6 5.4 4.3e-05 23.2 3.6 2.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EEQ73954.1 - 2.5e-05 24.3 0.7 0.00041 20.4 0.1 2.3 1 1 0 2 2 2 1 NADH(P)-binding LytR_C PF13399.1 EEQ73954.1 - 0.08 13.3 0.2 0.8 10.1 0.0 2.4 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator Zn_clus PF00172.13 EEQ73955.1 - 1.7e-11 43.7 12.4 1.7e-11 43.7 8.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3292 PF11696.3 EEQ73955.1 - 0.099 10.5 0.3 0.15 9.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) RRN7 PF11781.3 EEQ73955.1 - 0.22 11.0 5.5 0.46 10.0 3.8 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Rifin_STEVOR PF02009.11 EEQ73961.1 - 0.087 12.4 0.1 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family EphA2_TM PF14575.1 EEQ73961.1 - 0.1 12.9 0.3 0.24 11.8 0.2 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 EEQ73961.1 - 0.13 11.9 1.1 0.15 11.8 0.1 1.5 2 0 0 2 2 2 0 TMEM154 protein family DUF1517 PF07466.6 EEQ73961.1 - 0.14 11.1 0.3 0.23 10.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF2217 PF10265.4 EEQ73961.1 - 0.64 8.7 6.4 0.033 12.9 0.5 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) gpUL132 PF11359.3 EEQ73961.1 - 1 8.6 4.6 0.21 10.9 0.8 1.5 2 0 0 2 2 2 0 Glycoprotein UL132 Ribosomal_L19e PF01280.15 EEQ73962.1 - 7.7e-61 204.2 7.3 7.7e-61 204.2 5.1 1.9 1 1 1 2 2 2 1 Ribosomal protein L19e DUF349 PF03993.7 EEQ73962.1 - 0.066 13.3 12.5 0.64 10.2 4.7 3.0 2 1 1 3 3 3 0 Domain of Unknown Function (DUF349) RNase_H2-Ydr279 PF09468.5 EEQ73962.1 - 0.086 12.0 0.5 0.098 11.8 0.3 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF3554 PF12074.3 EEQ73963.1 - 4e-75 253.3 0.2 4.5e-74 249.9 0.0 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3554) HEAT_2 PF13646.1 EEQ73963.1 - 7.4e-37 125.5 44.4 7.9e-09 35.6 0.0 14.4 7 3 8 15 15 15 9 HEAT repeats HEAT PF02985.17 EEQ73963.1 - 3.6e-32 107.5 36.2 0.13 12.4 0.0 21.4 25 0 0 25 25 25 10 HEAT repeat HEAT_EZ PF13513.1 EEQ73963.1 - 2.9e-23 81.6 66.9 5.5e-05 23.5 0.0 22.8 15 4 10 25 25 25 10 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EEQ73963.1 - 1.3e-15 57.5 0.0 0.28 11.5 0.1 9.5 8 3 2 10 10 10 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EEQ73963.1 - 8.5e-10 38.7 0.2 0.13 12.1 0.1 7.4 7 3 1 8 8 8 3 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 EEQ73963.1 - 1.1e-07 31.9 4.0 0.43 10.4 0.0 6.9 7 1 1 8 8 8 2 Parkin co-regulated protein AAA_10 PF12846.2 EEQ73963.1 - 0.0046 16.4 4.5 16 4.8 0.9 5.5 4 1 0 4 4 4 1 AAA-like domain Arm PF00514.18 EEQ73963.1 - 0.67 9.8 4.8 17 5.4 0.1 5.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HA2 PF04408.18 EEQ73964.1 - 1e-18 67.2 0.0 2.6e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEQ73964.1 - 1.3e-10 40.9 0.1 3.1e-10 39.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEQ73964.1 - 3.4e-10 39.6 0.1 8.9e-10 38.3 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 EEQ73964.1 - 2.5e-07 30.5 0.0 7.8e-07 28.9 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 EEQ73964.1 - 5.5e-06 26.5 0.7 2.4e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EEQ73964.1 - 0.083 12.3 0.0 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family BRCT PF00533.21 EEQ73965.1 - 2.1e-05 24.5 0.0 4.9e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EEQ73965.1 - 0.01 15.6 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain DUF3602 PF12223.3 EEQ73965.1 - 0.053 13.8 0.3 0.053 13.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) KilA-N PF04383.8 EEQ73969.1 - 0.00013 21.5 0.0 0.002 17.7 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain Mg_trans_NIPA PF05653.9 EEQ73970.1 - 4.3e-87 291.8 25.5 6.1e-87 291.3 17.7 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EEQ73970.1 - 9.6e-07 29.0 7.3 9.6e-07 29.0 5.1 3.3 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EEQ73970.1 - 4.4e-05 23.5 9.2 4.4e-05 23.5 6.4 3.1 2 1 1 3 3 3 1 EamA-like transporter family Patatin PF01734.17 EEQ73971.1 - 2.2e-23 83.2 0.0 1e-22 81.0 0.0 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase DIM PF08194.7 EEQ73973.1 - 0.15 12.0 2.0 0.31 11.0 1.4 1.5 1 0 0 1 1 1 0 DIM protein GPI-anchored PF10342.4 EEQ73976.1 - 0.0052 17.2 0.2 0.01 16.3 0.1 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MOSC PF03473.12 EEQ73979.1 - 9.5e-14 51.0 0.0 1.6e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EEQ73979.1 - 7.7e-11 41.7 0.0 2.6e-10 40.0 0.0 1.9 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain SHMT PF00464.14 EEQ73980.1 - 7.3e-199 660.1 0.0 8.6e-199 659.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase MFS_1 PF07690.11 EEQ73983.1 - 2.1e-37 128.6 29.5 2.1e-37 128.6 20.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.23 EEQ73984.1 - 9.7e-79 264.6 0.0 1.2e-78 264.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ73984.1 - 9.1e-11 42.5 0.0 2.8e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ras PF00071.17 EEQ73985.1 - 1.1e-50 171.1 0.2 3.6e-50 169.5 0.1 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EEQ73985.1 - 5.1e-17 62.4 0.2 9.3e-15 55.1 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EEQ73985.1 - 5.7e-05 22.4 0.0 0.0005 19.3 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EEQ73985.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.13 EEQ73985.1 - 0.018 14.3 0.3 0.22 10.8 0.0 2.3 2 1 1 3 3 3 0 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EEQ73985.1 - 0.05 12.7 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_25 PF13481.1 EEQ73985.1 - 0.064 12.6 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRF PF06875.6 EEQ73985.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF SRPRB PF09439.5 EEQ73985.1 - 0.12 11.6 0.1 1 8.5 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit GST_N_2 PF13409.1 EEQ73987.1 - 5.5e-21 74.3 0.0 9.7e-21 73.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEQ73987.1 - 2.2e-16 59.4 0.1 3e-15 55.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EEQ73987.1 - 3.6e-05 23.6 0.0 8.2e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EEQ73987.1 - 3.7e-05 23.8 0.0 0.00061 19.9 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EEQ73987.1 - 0.00043 20.7 0.0 0.0014 19.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Mito_fiss_reg PF05308.6 EEQ73988.1 - 0.012 14.9 2.8 0.015 14.7 1.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 EEQ73988.1 - 0.13 11.5 3.3 0.18 11.0 2.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Adipogenin PF15202.1 EEQ73988.1 - 0.84 9.5 3.3 0.44 10.4 0.7 1.6 1 1 1 2 2 2 0 Adipogenin Mcp5_PH PF12814.2 EEQ73989.1 - 2.8e-49 166.0 0.2 5e-49 165.3 0.2 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.7 EEQ73989.1 - 0.29 10.8 15.9 1.6 8.4 11.0 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 EEQ73989.1 - 1 8.9 15.0 1.7 8.2 10.4 1.2 1 0 0 1 1 1 0 IncA protein DUF3584 PF12128.3 EEQ73989.1 - 1.6 5.9 9.1 2.3 5.4 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.4 EEQ73989.1 - 5.6 5.8 12.9 10 4.9 8.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4291 PF14124.1 EEQ73990.1 - 5e-59 198.9 0.2 6.5e-59 198.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Cyt-b5 PF00173.23 EEQ73991.1 - 6.2e-19 67.5 0.1 6.9e-19 67.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain EFP_N PF08207.7 EEQ73991.1 - 0.061 13.1 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain OB_NTP_bind PF07717.11 EEQ73992.1 - 8.1e-30 102.9 0.0 2.6e-29 101.3 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EEQ73992.1 - 5.6e-25 87.3 1.8 1.4e-24 85.9 0.0 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEQ73992.1 - 6.9e-12 45.0 0.0 1.8e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EEQ73992.1 - 4.6e-05 23.5 0.0 0.00017 21.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EEQ73992.1 - 5.6e-05 22.1 0.0 0.00011 21.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.24 EEQ73992.1 - 6.2e-05 22.5 0.1 0.00014 21.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase PWI PF01480.12 EEQ73992.1 - 0.0015 18.5 0.0 0.0037 17.3 0.0 1.6 1 0 0 1 1 1 1 PWI domain SRP54 PF00448.17 EEQ73992.1 - 0.0071 15.8 0.2 0.017 14.5 0.2 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Sigma54_activ_2 PF14532.1 EEQ73992.1 - 0.031 14.3 0.0 0.079 13.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 EEQ73992.1 - 0.16 12.2 2.5 0.19 12.0 0.0 2.5 2 1 0 2 2 2 0 ABC transporter Pkinase PF00069.20 EEQ73993.1 - 1.2e-39 136.0 0.0 1.2e-35 122.9 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ73993.1 - 2.7e-20 72.5 0.0 5.7e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ73993.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EEQ73993.1 - 0.2 10.5 0.0 0.41 9.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 EEQ73993.1 - 0.68 8.6 0.1 0.99 8.1 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase AMP-binding PF00501.23 EEQ73994.1 - 3.5e-241 799.8 0.0 6.9e-88 294.8 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EEQ73994.1 - 1e-180 599.1 0.0 8.8e-35 119.9 0.0 6.4 6 0 0 6 6 6 6 Condensation domain PP-binding PF00550.20 EEQ73994.1 - 1.5e-53 178.9 16.2 9.1e-09 35.4 0.3 7.0 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEQ73994.1 - 2.9e-19 69.7 0.0 4.6e-06 27.4 0.0 3.7 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.11 EEQ73994.1 - 0.0028 17.2 2.2 2.6 7.5 0.1 3.7 3 0 0 3 3 3 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Imm1 PF14430.1 EEQ73994.1 - 0.066 13.3 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Immunity protein Imm1 AATase PF07247.7 EEQ73994.1 - 0.093 11.2 1.8 2.9 6.3 0.0 4.0 5 1 0 5 5 5 0 Alcohol acetyltransferase Transferase PF02458.10 EEQ73994.1 - 0.1 11.0 0.0 3.4 6.0 0.0 3.0 3 0 0 3 3 3 0 Transferase family Ank_2 PF12796.2 EEQ73995.1 - 3.3e-53 177.9 0.1 4.6e-17 62.1 0.1 3.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ73995.1 - 8.6e-33 110.5 1.7 3.1e-09 36.1 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EEQ73995.1 - 9.5e-25 86.0 2.4 3.7e-07 30.1 0.0 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEQ73995.1 - 5.2e-24 84.1 9.8 9.4e-09 35.5 0.4 5.2 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ73995.1 - 3.1e-23 79.5 2.3 6.1e-08 32.1 0.0 5.7 6 0 0 6 6 6 4 Ankyrin repeat zf-DHHC PF01529.15 EEQ73995.1 - 4.8e-12 45.6 5.2 7.2e-08 32.0 0.0 2.9 3 0 0 3 3 3 2 DHHC palmitoyltransferase Cyclin PF08613.6 EEQ73996.1 - 9.6e-34 116.9 0.0 1.5e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EEQ73996.1 - 2.1e-05 24.0 0.1 3.3e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain OHCU_decarbox PF09349.5 EEQ73997.1 - 5.2e-51 173.0 0.6 7.2e-51 172.6 0.4 1.2 1 0 0 1 1 1 1 OHCU decarboxylase Pyridox_oxase_2 PF12766.2 EEQ73997.1 - 0.027 14.8 0.0 0.069 13.4 0.0 1.7 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DUF4404 PF14357.1 EEQ73997.1 - 0.58 10.6 3.4 0.39 11.1 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) zf-primase PF09329.6 EEQ73999.1 - 0.074 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Primase zinc finger B2 PF11473.3 EEQ73999.1 - 0.13 11.8 0.0 0.39 10.3 0.0 1.7 1 0 0 1 1 1 0 RNA binding protein B2 PhoD PF09423.5 EEQ74000.1 - 1.5e-69 234.7 1.9 1.1e-27 96.7 0.1 3.1 2 1 1 3 3 3 3 PhoD-like phosphatase WD40 PF00400.27 EEQ74001.1 - 2.2e-33 112.9 7.6 3.3e-07 29.9 0.0 8.1 8 0 0 8 8 8 5 WD domain, G-beta repeat VID27 PF08553.5 EEQ74001.1 - 0.15 10.2 0.1 8.8 4.4 0.0 2.2 2 0 0 2 2 2 0 VID27 cytoplasmic protein Neuromodulin PF06614.6 EEQ74001.1 - 2.7 7.9 11.7 0.054 13.4 3.0 1.9 2 0 0 2 2 2 0 Neuromodulin SRP9-21 PF05486.7 EEQ74002.1 - 1.3e-29 101.7 5.3 2.4e-29 100.8 3.7 1.4 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Ribonuc_red_sm PF00268.16 EEQ74003.1 - 2.2e-121 404.1 0.6 2.7e-121 403.9 0.4 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Glyco_hydro_16 PF00722.16 EEQ74004.1 - 3.4e-08 33.0 0.1 8.8e-08 31.6 0.0 1.7 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 SMI1_KNR4 PF09346.5 EEQ74005.1 - 1.3e-06 28.4 0.1 2.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.1 EEQ74005.1 - 0.0003 21.2 0.0 0.00051 20.4 0.0 1.4 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall SUKH_5 PF14567.1 EEQ74005.1 - 0.00097 18.5 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall Mito_carr PF00153.22 EEQ74006.1 - 3.7e-53 177.1 3.3 8.7e-20 70.2 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 EEQ74007.1 - 3.9e-14 51.8 8.9 2.2e-07 30.4 0.1 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF3312 PF11768.3 EEQ74007.1 - 0.02 13.1 0.0 0.034 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Cytochrom_D1 PF02239.11 EEQ74007.1 - 0.033 12.4 0.0 9.9 4.3 0.0 3.2 3 1 0 4 4 4 0 Cytochrome D1 heme domain DUF4613 PF15390.1 EEQ74007.1 - 0.05 11.7 0.0 0.11 10.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4613) DUF1308 PF07000.6 EEQ74008.1 - 2.1e-82 276.6 0.0 3.1e-82 276.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) Lung_7-TM_R PF06814.8 EEQ74009.1 - 1.4e-71 240.8 15.0 1.7e-71 240.5 10.4 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor PrgI PF12666.2 EEQ74009.1 - 0.12 12.5 19.0 0.98 9.6 0.5 4.4 2 1 1 4 4 4 0 PrgI family protein DUF2392 PF10288.4 EEQ74010.1 - 4.2e-27 94.5 0.0 7.7e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) DUF4112 PF13430.1 EEQ74011.1 - 7.3e-34 115.8 0.5 9.7e-34 115.4 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DCP2 PF05026.8 EEQ74012.1 - 1.1e-36 124.5 1.3 2.2e-36 123.5 0.9 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EEQ74012.1 - 9e-15 54.5 0.0 1.7e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain GCV_T PF01571.16 EEQ74013.1 - 5.5e-16 58.5 0.0 2.8e-14 53.0 0.0 2.2 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EEQ74013.1 - 0.00026 20.9 0.0 0.00047 20.1 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DnaJ PF00226.26 EEQ74014.1 - 1.2e-19 69.7 0.3 2.9e-19 68.5 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain LUC7 PF03194.10 EEQ74014.1 - 0.12 11.8 7.6 0.27 10.7 5.3 1.5 1 0 0 1 1 1 0 LUC7 N_terminus BTV_NS2 PF04514.7 EEQ74014.1 - 2.2 7.0 17.3 9.4 5.0 10.6 2.3 2 1 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Mei4 PF13971.1 EEQ74015.1 - 0.0083 15.1 2.2 0.016 14.2 1.5 1.6 1 1 0 1 1 1 1 Meiosis-specific protein Mei4 Amidohydro_2 PF04909.9 EEQ74016.1 - 3.4e-31 108.8 0.4 1.7e-30 106.5 0.3 1.9 1 1 0 1 1 1 1 Amidohydrolase DIOX_N PF14226.1 EEQ74017.1 - 1.4e-25 90.1 0.0 2.1e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EEQ74017.1 - 1.9e-16 60.1 0.0 3.4e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPP_enzyme_N PF02776.13 EEQ74018.1 - 8.9e-35 119.6 1.0 1.8e-34 118.6 0.0 2.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EEQ74018.1 - 3.1e-20 72.3 0.0 1.1e-19 70.5 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EEQ74018.1 - 1.5e-14 53.8 0.0 3.4e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EEQ74018.1 - 0.031 13.0 0.0 0.054 12.2 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EEQ74018.1 - 0.056 12.3 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Flavin_Reduct PF01613.13 EEQ74019.1 - 1.4e-12 47.6 0.0 2.1e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 EEQ74019.1 - 0.00038 20.0 0.0 0.00057 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF447) p450 PF00067.17 EEQ74021.1 - 3.9e-23 81.6 0.0 2.9e-17 62.3 0.0 3.0 1 1 1 2 2 2 2 Cytochrome P450 NmrA PF05368.8 EEQ74022.1 - 3.8e-21 75.4 0.0 4.7e-20 71.8 0.0 2.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEQ74022.1 - 3.8e-15 56.3 0.0 7.9e-15 55.3 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEQ74022.1 - 0.00036 20.0 0.0 0.0012 18.3 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EEQ74022.1 - 0.00091 18.3 0.0 0.0014 17.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EEQ74022.1 - 0.001 17.8 0.0 0.0021 16.8 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 EEQ74022.1 - 0.076 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EEQ74022.1 - 0.098 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain MFS_1 PF07690.11 EEQ74023.1 - 6e-42 143.6 35.7 7.4e-42 143.3 24.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ74023.1 - 1.5e-12 46.8 10.4 1.5e-12 46.8 7.2 2.3 1 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EEQ74023.1 - 4.3e-08 31.8 3.9 6.5e-08 31.2 2.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LDB19 PF13002.2 EEQ74025.1 - 5.4e-74 247.8 0.6 2e-73 246.0 0.1 1.9 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.24 EEQ74025.1 - 0.00015 21.6 0.0 0.00039 20.2 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF4606 PF15379.1 EEQ74025.1 - 0.12 12.5 0.2 0.27 11.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4606) PIG-L PF02585.12 EEQ74027.1 - 4.3e-26 91.9 0.0 6.5e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Ferric_reduct PF01794.14 EEQ74027.1 - 0.015 15.3 1.2 0.018 15.1 0.2 1.6 2 0 0 2 2 2 0 Ferric reductase like transmembrane component ATP13 PF12921.2 EEQ74028.1 - 8.6e-33 112.3 0.0 1.6e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_2 PF13041.1 EEQ74028.1 - 3.3e-08 33.3 0.3 0.0035 17.2 0.0 3.7 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 EEQ74028.1 - 2e-06 27.6 0.2 0.03 14.5 0.0 5.0 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.15 EEQ74028.1 - 0.022 14.7 1.0 4 7.6 0.0 4.1 5 0 0 5 5 5 0 PPR repeat LSM PF01423.17 EEQ74029.1 - 1.8e-12 46.6 1.0 1.4e-08 34.1 0.1 2.2 2 0 0 2 2 2 2 LSM domain GTP_EFTU PF00009.22 EEQ74030.1 - 2e-21 76.2 0.0 7e-21 74.5 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EEQ74030.1 - 1.1e-15 57.5 0.1 2.4e-15 56.5 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EEQ74030.1 - 1.1e-08 35.0 1.5 5.2e-08 32.8 0.6 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 EEQ74030.1 - 0.00056 19.4 0.2 0.66 9.4 0.1 3.4 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EEQ74030.1 - 0.0049 17.3 0.2 0.069 13.6 0.1 2.9 2 1 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EEQ74030.1 - 0.0068 16.3 0.0 0.021 14.7 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 EEQ74030.1 - 0.049 13.3 0.1 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EEQ74030.1 - 0.099 12.4 0.6 0.26 11.0 0.1 1.9 2 0 0 2 2 2 0 Dynamin family GTP_EFTU_D4 PF14578.1 EEQ74030.1 - 0.49 10.0 3.2 0.44 10.2 0.6 2.2 2 1 0 2 2 2 0 Elongation factor Tu domain 4 DUF4662 PF15578.1 EEQ74031.1 - 4.1 6.8 6.0 0.44 10.0 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4662) SNF2_N PF00176.18 EEQ74032.1 - 1.7e-70 237.2 0.0 2.4e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EEQ74032.1 - 6.8e-23 80.6 0.0 1.2e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EEQ74032.1 - 1.3e-11 44.1 0.0 3.9e-11 42.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EEQ74032.1 - 6.4e-07 29.2 8.5 1.2e-06 28.4 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 EEQ74032.1 - 6.3e-05 22.8 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 EEQ74032.1 - 0.00021 20.9 7.6 0.00039 20.0 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ74032.1 - 0.00027 20.6 7.8 0.00051 19.8 5.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEQ74032.1 - 0.00036 20.1 6.8 0.00061 19.3 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ74032.1 - 0.011 15.4 6.6 0.022 14.5 4.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EEQ74032.1 - 0.031 14.1 7.0 0.058 13.2 4.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EEQ74032.1 - 0.49 10.1 5.4 1.2 8.9 3.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger SQS_PSY PF00494.14 EEQ74033.1 - 1.3e-46 159.0 0.0 1.9e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase CorA PF01544.13 EEQ74034.1 - 2.4e-29 102.3 2.1 1.1e-20 73.9 0.4 3.1 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein DNA_pol_A PF00476.15 EEQ74035.1 - 4.3e-101 338.3 0.0 5.9e-101 337.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 EEQ74035.1 - 0.076 12.4 0.1 2.1 7.8 0.0 2.6 1 1 0 1 1 1 0 3'-5' exonuclease DUF1357 PF07094.6 EEQ74036.1 - 0.14 11.5 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1357) UPF0052 PF01933.13 EEQ74037.1 - 2.1e-51 175.0 0.0 2.7e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 PI3_PI4_kinase PF00454.22 EEQ74038.1 - 4.4e-46 157.2 0.0 1e-45 156.0 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EEQ74038.1 - 3.3e-34 117.8 6.1 5.4e-34 117.1 0.1 3.2 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 EEQ74038.1 - 1.7e-08 33.7 0.1 5e-08 32.2 0.1 1.9 1 0 0 1 1 1 1 FATC domain DUF1353 PF07087.6 EEQ74038.1 - 0.0017 17.7 0.0 0.088 12.2 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1353) DUF3414 PF11894.3 EEQ74039.1 - 0 1396.9 12.5 0 1396.5 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Cullin PF00888.17 EEQ74040.1 - 9.9e-122 407.4 0.1 7.2e-120 401.2 0.0 2.0 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EEQ74040.1 - 2.2e-24 85.0 0.8 6.5e-24 83.5 0.5 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain HbrB PF08539.6 EEQ74040.1 - 0.022 14.6 0.1 0.05 13.4 0.1 1.7 1 0 0 1 1 1 0 HbrB-like SOG2 PF10428.4 EEQ74040.1 - 0.045 12.4 4.6 0.077 11.6 3.2 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Penicillinase_R PF03965.11 EEQ74040.1 - 0.98 9.5 4.5 0.86 9.7 0.2 3.1 4 0 0 4 4 4 0 Penicillinase repressor Dak1 PF02733.12 EEQ74041.1 - 2e-113 378.2 0.8 2.8e-113 377.8 0.5 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EEQ74041.1 - 6.9e-43 146.3 0.0 1.4e-42 145.3 0.0 1.6 1 0 0 1 1 1 1 DAK2 domain LSM PF01423.17 EEQ74044.1 - 4e-18 64.7 0.1 5.7e-18 64.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain Baculo_44 PF04631.7 EEQ74044.1 - 0.1 11.1 0.0 0.12 10.9 0.0 1.0 1 0 0 1 1 1 0 Baculovirus hypothetical protein CAV_VP3 PF04771.7 EEQ74044.1 - 0.15 12.0 0.1 3.6 7.5 0.0 2.0 1 1 1 2 2 2 0 Chicken anaemia virus VP-3 protein GATA PF00320.22 EEQ74045.1 - 8e-06 25.1 4.8 0.00029 20.1 0.6 2.6 2 0 0 2 2 2 2 GATA zinc finger Rad17 PF03215.10 EEQ74045.1 - 0.25 9.9 0.2 0.37 9.4 0.1 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Rep_fac-A_3 PF08661.6 EEQ74046.1 - 2e-24 85.6 0.0 2.3e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Ten1 PF12658.2 EEQ74046.1 - 0.0029 17.3 0.0 0.048 13.4 0.0 2.0 1 1 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 EEQ74046.1 - 0.0087 15.6 0.2 0.015 14.8 0.2 1.3 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit Amidase_2 PF01510.20 EEQ74048.1 - 3.6e-11 43.2 0.3 5.8e-11 42.5 0.2 1.3 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Glyco_hydro_16 PF00722.16 EEQ74051.1 - 7.6e-44 149.2 1.9 1.1e-43 148.6 1.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1191 PF06697.7 EEQ74051.1 - 0.035 12.9 0.0 0.051 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Prp19_bind PF06991.6 EEQ74052.1 - 1.7e-42 145.6 26.2 1.7e-42 145.6 18.2 2.4 3 0 0 3 3 3 1 Splicing factor, Prp19-binding domain TRAPP PF04051.11 EEQ74053.1 - 4e-35 120.5 0.0 5.2e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component NAD_kinase PF01513.16 EEQ74054.1 - 1.5e-67 227.4 0.0 1.9e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DUF3626 PF12294.3 EEQ74054.1 - 0.023 13.7 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) p450 PF00067.17 EEQ74056.1 - 1.7e-21 76.2 0.0 2.4e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 UbiA PF01040.13 EEQ74057.1 - 1.2e-06 27.9 1.0 2.1e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 UbiA prenyltransferase family Gly_transf_sug PF04488.10 EEQ74058.1 - 1e-05 25.8 0.0 1.7e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EEQ74058.1 - 3.7e-05 23.0 0.0 6.7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Trp_DMAT PF11991.3 EEQ74059.1 - 1.8e-73 247.8 0.0 2.4e-73 247.4 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase WASH-7_C PF14746.1 EEQ74060.1 - 0.027 14.0 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal Las1 PF04031.8 EEQ74064.1 - 5.8e-45 152.6 0.1 9.3e-45 152.0 0.0 1.3 1 0 0 1 1 1 1 Las1-like Lactamase_B PF00753.22 EEQ74065.1 - 9e-30 103.7 1.9 1.2e-29 103.3 1.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EEQ74065.1 - 1.7e-05 24.4 0.5 2.7e-05 23.7 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.15 EEQ74065.1 - 0.034 13.4 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DUF1264 PF06884.6 EEQ74066.1 - 2.6e-67 225.5 0.0 3.4e-67 225.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Peptidase_S24 PF00717.18 EEQ74067.1 - 1.3e-07 31.1 0.0 2.2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EEQ74067.1 - 2.7e-05 23.7 0.0 0.001 18.5 0.0 2.6 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 PBP PF01161.15 EEQ74068.1 - 1.3e-12 47.7 0.0 2e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ABC_tran_2 PF12848.2 EEQ74068.1 - 0.0085 15.9 1.4 0.018 14.8 1.0 1.5 1 0 0 1 1 1 1 ABC transporter Ribosomal_L4 PF00573.17 EEQ74069.1 - 8.9e-47 158.9 0.0 1.1e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family ECH_C PF13766.1 EEQ74070.1 - 1.4e-40 138.1 0.5 2.5e-40 137.3 0.3 1.4 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EEQ74070.1 - 1.1e-26 93.4 0.1 1.4e-25 89.8 0.0 2.0 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family DUF1805 PF08827.6 EEQ74071.1 - 0.32 10.8 5.4 0.66 9.8 3.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) DUF4407 PF14362.1 EEQ74071.1 - 7.4 5.4 11.4 8.7 5.1 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OTT_1508_deam PF14441.1 EEQ74072.1 - 3.8e-20 72.1 0.0 8.1e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase CBS PF00571.23 EEQ74074.1 - 4.3e-25 87.2 7.1 4.4e-11 42.3 0.1 4.4 4 0 0 4 4 4 4 CBS domain CRAL_TRIO PF00650.15 EEQ74075.1 - 2.2e-36 124.7 0.0 3e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EEQ74075.1 - 2.5e-11 43.5 0.2 1.1e-10 41.4 0.0 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EEQ74075.1 - 1.2e-06 28.5 0.0 1.7e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pol_alpha_B_N PF08418.5 EEQ74076.1 - 1.7e-55 188.3 0.5 2.4e-55 187.7 0.4 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 EEQ74076.1 - 7.1e-34 116.8 0.1 4.1e-33 114.3 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Apc13p PF05839.6 EEQ74077.1 - 8.8e-21 73.6 0.8 1.1e-17 63.8 0.0 2.1 2 0 0 2 2 2 2 Apc13p protein IF-2B PF01008.12 EEQ74078.1 - 6.8e-76 254.9 0.1 1e-75 254.3 0.1 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family LIN37 PF15306.1 EEQ74078.1 - 0.0037 17.2 5.6 0.0037 17.2 3.9 2.2 1 1 1 2 2 2 1 LIN37 DVL PF08137.7 EEQ74078.1 - 0.56 9.6 4.2 1 8.8 2.9 1.5 1 0 0 1 1 1 0 DVL family Kinesin PF00225.18 EEQ74079.1 - 6.6e-115 383.3 0.0 6.6e-115 383.3 0.0 1.4 2 0 0 2 2 2 1 Kinesin motor domain DUF1643 PF07799.7 EEQ74079.1 - 0.033 13.8 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) DUF87 PF01935.12 EEQ74079.1 - 0.91 9.2 5.3 0.77 9.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 LMBR1 PF04791.11 EEQ74079.1 - 6.7 5.1 4.9 3.5 6.1 1.1 1.8 2 0 0 2 2 2 0 LMBR1-like membrane protein TIM PF00121.13 EEQ74083.1 - 3.4e-89 298.1 0.0 3.8e-89 297.9 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Peptidase_C80 PF11713.3 EEQ74083.1 - 0.057 13.2 0.0 0.13 12.0 0.0 1.7 1 1 0 1 1 1 0 Peptidase C80 family Arm PF00514.18 EEQ74084.1 - 6e-65 213.0 29.6 1.4e-10 40.5 0.1 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EEQ74084.1 - 1.5e-21 76.4 16.4 4e-06 27.0 0.5 7.6 3 3 4 8 8 8 6 HEAT repeats HEAT PF02985.17 EEQ74084.1 - 2.5e-17 61.3 13.7 0.05 13.6 0.1 9.3 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.1 EEQ74084.1 - 9e-16 57.8 11.7 0.0013 19.1 0.0 8.4 7 2 2 9 9 8 5 HEAT-like repeat Adaptin_N PF01602.15 EEQ74084.1 - 1.2e-12 47.0 11.0 3.2e-08 32.3 0.9 3.2 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.7 EEQ74084.1 - 6.2e-09 34.3 1.0 1.1e-08 33.5 0.5 1.5 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 EEQ74084.1 - 6.4e-09 35.3 2.1 0.00016 20.9 1.3 2.9 2 1 1 3 3 3 2 V-ATPase subunit H Arm_2 PF04826.8 EEQ74084.1 - 8.2e-09 34.9 8.2 4.7e-05 22.6 3.3 2.8 1 1 1 2 2 2 2 Armadillo-like Vac14_Fab1_bd PF12755.2 EEQ74084.1 - 0.014 15.7 0.3 1.1 9.7 0.1 3.3 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.3 EEQ74084.1 - 0.033 14.0 5.6 9.8 6.1 0.0 4.6 2 1 5 7 7 7 0 V-ATPase subunit H HEAT_PBS PF03130.11 EEQ74084.1 - 0.034 14.5 10.3 4.7 7.9 0.8 6.6 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat EXOSC1 PF10447.4 EEQ74085.1 - 1e-28 99.0 0.1 1.9e-28 98.2 0.1 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EEQ74085.1 - 1.8e-14 52.7 0.0 2.8e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region GHBP PF12772.2 EEQ74085.1 - 0.13 11.6 4.3 0.17 11.2 3.0 1.1 1 0 0 1 1 1 0 Growth hormone receptor binding Pol_alpha_B_N PF08418.5 EEQ74085.1 - 1.4 8.4 5.7 1.8 8.0 4.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal GTP_EFTU PF00009.22 EEQ74086.1 - 4.5e-38 130.5 0.0 1.1e-37 129.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EEQ74086.1 - 7.4e-16 57.7 0.0 2.1e-15 56.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EEQ74086.1 - 5.5e-08 32.8 0.0 1.4e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EEQ74086.1 - 4.3e-07 29.6 0.0 8.8e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EEQ74086.1 - 0.00013 21.4 0.0 0.016 14.7 0.0 2.7 1 1 1 2 2 2 1 Elongation factor G, domain IV SET PF00856.23 EEQ74086.1 - 0.11 12.7 1.4 0.46 10.7 0.0 2.5 3 0 0 3 3 3 0 SET domain DUF4604 PF15377.1 EEQ74087.1 - 2.8e-28 99.1 12.9 3.4e-28 98.8 9.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Prp19 PF08606.6 EEQ74088.1 - 4.7e-33 112.7 0.9 1.1e-32 111.5 0.6 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 EEQ74088.1 - 3.2e-16 58.5 1.9 6.4e-07 29.0 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EEQ74088.1 - 3.9e-10 39.1 0.2 7.2e-06 25.0 0.0 2.1 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.6 EEQ74088.1 - 1.6e-07 31.2 0.4 0.0015 18.2 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EEQ74088.1 - 0.0032 15.8 0.0 0.044 12.0 0.0 2.2 2 0 0 2 2 2 1 Cytochrome D1 heme domain DUF3312 PF11768.3 EEQ74088.1 - 0.009 14.2 0.0 0.015 13.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) zf-Nse PF11789.3 EEQ74088.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 EEQ74089.1 - 0.0078 15.9 3.0 0.014 15.1 2.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEQ74089.1 - 0.024 14.6 6.9 0.11 12.5 4.8 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ74089.1 - 0.062 13.1 4.1 0.21 11.4 2.9 1.9 1 1 1 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.20 EEQ74089.1 - 0.17 11.5 3.7 0.96 9.1 3.0 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ74089.1 - 0.28 10.8 4.3 0.72 9.5 3.0 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) L51_S25_CI-B8 PF05047.11 EEQ74090.1 - 1.4e-14 53.5 0.0 2.3e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.3 EEQ74091.1 - 3.6e-34 116.9 1.6 6.2e-34 116.2 1.1 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EEQ74091.1 - 6.1e-17 61.0 0.0 1.7e-16 59.5 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ74091.1 - 1.9e-12 46.9 0.0 3.3e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ74091.1 - 4.4e-07 29.6 0.0 1.1e-06 28.3 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L10 PF00466.15 EEQ74092.1 - 7.7e-18 64.2 0.0 1.3e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 DUF3722 PF12519.3 EEQ74093.1 - 1.8e-73 246.9 0.5 3.3e-39 134.6 0.8 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3722) FHA PF00498.21 EEQ74094.1 - 1.2e-13 51.0 0.0 2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EEQ74094.1 - 4.2e-06 26.4 9.4 7.9e-06 25.6 6.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EEQ74094.1 - 0.00073 19.5 4.0 0.0016 18.4 2.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EEQ74094.1 - 0.0089 15.7 6.6 0.015 14.9 4.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EEQ74094.1 - 0.009 15.6 8.1 0.022 14.4 5.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEQ74094.1 - 0.027 14.3 1.3 0.054 13.3 0.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-H2C2_2 PF13465.1 EEQ74094.1 - 0.088 13.1 1.8 0.32 11.3 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger double domain zf-C3HC4_2 PF13923.1 EEQ74094.1 - 0.12 12.3 9.9 0.23 11.5 6.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EEQ74094.1 - 0.34 10.9 6.3 0.65 10.0 4.3 1.5 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 EEQ74094.1 - 0.4 10.4 5.8 0.7 9.6 4.0 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.1 EEQ74094.1 - 8.8 6.2 8.4 23 4.9 5.8 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Bestrophin PF01062.16 EEQ74095.1 - 2.6e-35 121.7 0.1 5.5e-25 87.9 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Atrophin-1 PF03154.10 EEQ74096.1 - 0.057 11.5 12.1 0.078 11.1 8.4 1.2 1 0 0 1 1 1 0 Atrophin-1 family C9orf72-like PF15019.1 EEQ74097.1 - 0.059 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 C9orf72-like protein family Vps16_N PF04841.8 EEQ74098.1 - 1.9e-99 333.0 0.0 3.1e-99 332.3 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 EEQ74098.1 - 1.1e-82 277.5 0.0 1.6e-82 277.0 0.0 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region PQQ_3 PF13570.1 EEQ74098.1 - 0.071 13.4 0.1 7 7.0 0.0 3.3 2 1 1 3 3 3 0 PQQ-like domain Alb1 PF09135.6 EEQ74099.1 - 9.2e-28 97.0 7.5 9.2e-28 97.0 5.2 1.6 2 0 0 2 2 2 1 Alb1 Glyco_hydro_4C PF11975.3 EEQ74099.1 - 0.05 13.3 0.2 0.067 12.9 0.2 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain UCH PF00443.24 EEQ74100.1 - 1.9e-35 122.2 0.0 2.6e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEQ74100.1 - 9.4e-07 28.5 0.0 2.7e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3509 PF12021.3 EEQ74100.1 - 0.2 11.4 3.1 0.35 10.6 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) EF-hand_8 PF13833.1 EEQ74101.1 - 0.0021 17.6 0.0 0.69 9.5 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 EEQ74101.1 - 0.0076 16.1 0.0 3.2 7.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 EEQ74101.1 - 0.071 13.2 0.0 1.8 8.7 0.0 2.6 2 1 0 2 2 2 0 EF-hand domain pair PUL PF08324.6 EEQ74102.1 - 4.8e-38 130.4 0.0 6.5e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 EEQ74102.1 - 5.1e-35 120.4 0.0 8.4e-35 119.7 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 EEQ74102.1 - 1.9e-16 59.6 0.0 3.4e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EEQ74102.1 - 7.8e-05 22.8 0.4 0.00047 20.3 0.3 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EEQ74102.1 - 0.00018 21.2 0.0 0.00058 19.6 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin domain TraF PF13728.1 EEQ74102.1 - 0.00087 18.8 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 F plasmid transfer operon protein DUF2847 PF11009.3 EEQ74102.1 - 0.017 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) DIM1 PF02966.11 EEQ74102.1 - 0.059 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 Redoxin PF08534.5 EEQ74102.1 - 0.082 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.16 EEQ74102.1 - 0.092 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Pro_isomerase PF00160.16 EEQ74103.1 - 1.1e-38 132.8 0.0 2.3e-38 131.8 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 EEQ74103.1 - 3.1e-08 33.1 0.2 7.6e-08 31.8 0.1 1.6 1 1 0 1 1 1 1 Rtf2 RING-finger U-box PF04564.10 EEQ74103.1 - 0.021 14.7 0.0 0.15 12.0 0.0 2.3 1 1 1 2 2 2 0 U-box domain YjeF_N PF03853.10 EEQ74104.1 - 1.6e-32 112.4 0.1 2.3e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EEQ74104.1 - 4.9e-11 43.0 3.5 9.9e-11 42.1 2.4 1.5 1 0 0 1 1 1 1 FDF domain NTP_transferase PF00483.18 EEQ74104.1 - 0.0043 16.3 0.0 0.0079 15.5 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase AAA_26 PF13500.1 EEQ74104.1 - 0.036 13.6 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 EEQ74105.1 - 8.4e-63 212.4 0.5 1.5e-49 168.9 0.0 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EEQ74105.1 - 3.2e-19 69.3 0.9 5.4e-19 68.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EEQ74105.1 - 7.9e-09 35.7 0.1 4.5e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEQ74105.1 - 6.7e-06 25.7 0.1 1.6e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain Herpes_Helicase PF02689.9 EEQ74105.1 - 4.8e-05 21.3 0.0 0.0002 19.3 0.0 1.9 2 0 0 2 2 2 1 Helicase AAA PF00004.24 EEQ74105.1 - 0.00013 22.1 0.1 0.00063 19.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.1 EEQ74105.1 - 0.00016 21.7 2.0 0.00063 19.8 0.1 2.9 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 EEQ74105.1 - 0.0007 19.6 0.4 0.0085 16.0 0.0 2.6 3 0 0 3 3 2 1 AAA ATPase domain PhoH PF02562.11 EEQ74105.1 - 0.0019 17.4 0.0 0.023 13.9 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein TrwB_AAD_bind PF10412.4 EEQ74105.1 - 0.0031 16.2 0.0 0.0076 14.9 0.0 1.6 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_14 PF13173.1 EEQ74105.1 - 0.0034 17.2 0.0 0.014 15.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EEQ74105.1 - 0.007 15.3 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein RNA_helicase PF00910.17 EEQ74105.1 - 0.015 15.4 0.2 0.072 13.2 0.0 2.4 3 1 0 3 3 1 0 RNA helicase DUF2075 PF09848.4 EEQ74105.1 - 0.017 14.1 0.0 0.048 12.6 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 EEQ74105.1 - 0.017 14.6 4.5 0.38 10.2 0.0 3.3 4 1 1 5 5 4 0 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 EEQ74105.1 - 0.02 14.3 0.0 0.33 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain DUF258 PF03193.11 EEQ74105.1 - 0.058 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Mg_chelatase PF01078.16 EEQ74105.1 - 0.066 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EEQ74105.1 - 0.092 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.1 EEQ74105.1 - 0.11 12.0 0.0 0.11 12.0 0.0 3.0 4 1 0 4 4 3 0 AAA domain Arch_ATPase PF01637.13 EEQ74105.1 - 0.15 11.7 0.4 0.5 10.0 0.3 1.9 1 1 0 1 1 1 0 Archaeal ATPase RebB PF11747.3 EEQ74105.1 - 0.21 11.4 13.0 0.56 10.1 9.0 1.7 1 0 0 1 1 1 0 Killing trait PTCB-BRCT PF12738.2 EEQ74106.1 - 2.3e-19 68.9 0.1 8.1e-10 38.4 0.0 3.0 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.21 EEQ74106.1 - 5.3e-12 45.7 0.0 9.6e-06 25.6 0.0 3.7 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain Dynamin_N PF00350.18 EEQ74107.1 - 6.2e-17 61.9 0.1 6.2e-17 61.9 0.1 2.3 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EEQ74107.1 - 1e-09 38.3 0.2 8e-09 35.4 0.1 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEQ74107.1 - 1.3e-06 28.0 2.4 5.2e-06 26.0 0.7 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EEQ74107.1 - 0.003 18.0 0.4 0.24 11.9 0.1 3.2 2 1 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 EEQ74107.1 - 0.022 15.0 0.1 0.41 10.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF2205 PF10224.4 EEQ74107.1 - 0.035 13.6 2.5 0.092 12.3 0.2 2.6 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) FeoB_N PF02421.13 EEQ74107.1 - 0.044 13.0 1.5 17 4.6 0.1 3.3 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_29 PF13555.1 EEQ74107.1 - 0.053 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Snf7 PF03357.16 EEQ74108.1 - 3.4e-34 117.7 18.0 3.4e-34 117.7 12.5 1.9 1 1 1 2 2 2 1 Snf7 V_ATPase_I PF01496.14 EEQ74108.1 - 0.0026 15.7 3.7 0.0031 15.4 2.5 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Ist1 PF03398.9 EEQ74108.1 - 0.082 12.3 5.3 0.12 11.7 3.7 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway PP2C PF00481.16 EEQ74109.1 - 1.2e-63 214.8 0.1 1.2e-51 175.6 0.1 3.2 2 1 1 3 3 3 3 Protein phosphatase 2C Mhr1 PF12829.2 EEQ74110.1 - 7.7e-32 108.9 0.1 1.7e-31 107.9 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination DUF3343 PF11823.3 EEQ74110.1 - 0.025 13.8 0.1 0.083 12.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) Atg14 PF10186.4 EEQ74111.1 - 4.7e-27 94.7 1.9 7.9e-27 93.9 1.3 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EEQ74111.1 - 9.2e-06 24.9 2.7 2.8e-05 23.3 1.9 1.8 1 1 0 1 1 1 1 Autophagy protein Apg6 DUF4391 PF14335.1 EEQ74111.1 - 0.00069 19.0 0.5 0.0012 18.2 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4391) AAA_13 PF13166.1 EEQ74111.1 - 0.082 11.3 8.0 0.12 10.7 5.5 1.1 1 0 0 1 1 1 0 AAA domain Sec8_exocyst PF04048.9 EEQ74111.1 - 0.3 10.7 9.0 0.3 10.6 0.3 2.4 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain DUF607 PF04678.8 EEQ74111.1 - 1.6 8.6 5.1 1.3 8.9 1.9 2.0 2 1 0 2 2 2 0 Protein of unknown function, DUF607 RTC4 PF14474.1 EEQ74112.1 - 3.2e-12 46.4 0.0 4.9e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 RTC4-like domain Papo_T_antigen PF02380.10 EEQ74113.1 - 0.12 12.3 0.1 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 T-antigen specific domain IFN-gamma PF00714.12 EEQ74114.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Interferon gamma Zn_clus PF00172.13 EEQ74115.1 - 6.6e-07 29.1 14.6 1.2e-06 28.3 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zip PF02535.17 EEQ74115.1 - 4 6.3 10.2 0.14 11.1 2.7 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter F-box-like PF12937.2 EEQ74116.1 - 0.0019 17.8 0.5 0.0039 16.8 0.4 1.5 1 0 0 1 1 1 1 F-box-like PalH PF08733.5 EEQ74117.1 - 3.9e-98 328.4 0.2 1.7e-97 326.3 0.1 1.8 1 1 0 1 1 1 1 PalH/RIM21 PLAC8 PF04749.12 EEQ74118.1 - 1.1e-24 87.0 15.1 1.4e-24 86.6 10.4 1.2 1 0 0 1 1 1 1 PLAC8 family TIP120 PF08623.5 EEQ74120.1 - 9.9e-63 210.7 0.1 8.9e-60 201.1 0.0 4.0 3 1 1 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EEQ74120.1 - 1.2e-18 67.1 18.1 0.0018 18.4 0.0 8.2 6 1 3 9 9 9 6 HEAT repeats HEAT PF02985.17 EEQ74120.1 - 8.6e-15 53.4 16.4 0.21 11.7 0.0 11.7 13 0 0 13 13 11 4 HEAT repeat Adaptin_N PF01602.15 EEQ74120.1 - 9.9e-07 27.4 5.8 0.24 9.6 0.0 7.1 5 3 2 7 7 7 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 EEQ74120.1 - 6.8e-06 26.3 0.4 0.56 10.6 0.0 6.5 7 2 0 7 7 7 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EEQ74120.1 - 1.1e-05 25.7 26.2 3 8.4 0.0 12.5 11 3 4 15 15 15 2 HEAT-like repeat UME PF08064.8 EEQ74120.1 - 0.00088 19.2 0.2 0.063 13.2 0.0 4.2 4 1 1 5 5 4 1 UME (NUC010) domain Cnd1 PF12717.2 EEQ74120.1 - 0.0022 17.8 0.0 0.18 11.6 0.0 4.3 4 2 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 EEQ74120.1 - 0.0022 17.8 0.1 0.0022 17.8 0.1 4.5 6 0 0 6 6 6 1 Protein of unknown function (DUF2435) HEAT_PBS PF03130.11 EEQ74120.1 - 0.0091 16.3 1.1 1.6 9.3 0.0 5.3 5 0 0 5 5 3 1 PBS lyase HEAT-like repeat ParcG PF10274.4 EEQ74120.1 - 0.025 14.5 2.4 15 5.4 0.0 5.3 6 0 0 6 6 6 0 Parkin co-regulated protein DUF1546 PF07571.8 EEQ74120.1 - 0.056 13.5 0.0 1.5 8.9 0.0 3.6 4 0 0 4 4 3 0 Protein of unknown function (DUF1546) CRM1_C PF08767.6 EEQ74120.1 - 0.22 10.4 0.7 48 2.7 0.0 3.8 4 0 0 4 4 4 0 CRM1 C terminal DUF1510 PF07423.6 EEQ74121.1 - 0.0011 18.3 7.1 0.0015 17.9 4.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) GAGA_bind PF06217.7 EEQ74121.1 - 5.9 6.7 7.8 30 4.4 0.0 2.0 2 0 0 2 2 2 0 GAGA binding protein-like family TRAM_LAG1_CLN8 PF03798.11 EEQ74122.1 - 5.4e-34 117.4 18.8 5.4e-34 117.4 13.0 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EEQ74122.1 - 6e-23 80.1 0.3 1.6e-22 78.7 0.0 1.9 2 0 0 2 2 2 1 TRAM1-like protein DUF1680 PF07944.7 EEQ74123.1 - 1.1e-19 70.1 0.0 9.9e-17 60.3 0.0 2.1 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) Prenyltrans_1 PF13243.1 EEQ74123.1 - 0.00058 19.8 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 Prenyltransferase-like Glyco_hydro_88 PF07470.8 EEQ74123.1 - 0.016 14.2 0.8 0.024 13.6 0.5 1.2 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 Zn_clus PF00172.13 EEQ74124.1 - 2.8e-06 27.1 9.8 5.3e-06 26.2 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SET PF00856.23 EEQ74125.1 - 1.7e-11 44.7 0.2 4.5e-10 40.0 0.1 2.3 1 1 0 1 1 1 1 SET domain Transglut_core3 PF13471.1 EEQ74125.1 - 0.058 13.1 0.2 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily Ferric_reduct PF01794.14 EEQ74126.1 - 0.069 13.2 2.2 0.13 12.3 1.5 1.5 1 1 0 1 1 1 0 Ferric reductase like transmembrane component SdpI PF13630.1 EEQ74126.1 - 0.15 11.7 5.2 0.11 12.2 0.8 2.1 1 1 1 2 2 2 0 SdpI/YhfL protein family DUF1129 PF06570.6 EEQ74126.1 - 0.28 10.4 1.2 3.1 7.0 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) UPF0506 PF11703.3 EEQ74128.1 - 0.092 12.7 0.1 0.092 12.7 0.1 2.7 1 1 1 2 2 2 0 UPF0506 Sugar_tr PF00083.19 EEQ74129.1 - 3.2e-95 319.3 20.3 5.7e-95 318.5 14.0 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ74129.1 - 8.7e-29 100.3 48.6 1.2e-26 93.2 17.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEQ74129.1 - 0.00025 19.3 1.3 0.00041 18.6 0.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 EEQ74129.1 - 0.00036 19.3 1.6 0.00049 18.8 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF791) Fungal_trans_2 PF11951.3 EEQ74130.1 - 0.14 10.7 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Transglut_core PF01841.14 EEQ74131.1 - 4.3e-13 49.4 0.0 8.5e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 EEQ74131.1 - 0.11 11.7 0.0 1.9 7.7 0.0 2.6 2 1 0 2 2 2 0 Transglutaminase-like domain Ras PF00071.17 EEQ74132.1 - 5.6e-27 94.1 0.1 8.3e-27 93.5 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ74132.1 - 6.7e-20 71.7 0.0 1.3e-19 70.8 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ74132.1 - 1.5e-06 27.5 0.2 2.4e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEQ74132.1 - 0.00011 21.4 0.1 0.00016 20.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEQ74132.1 - 0.083 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 EEQ74132.1 - 0.56 8.8 8.3 0.18 10.4 0.0 2.6 1 1 1 2 2 2 0 G-protein alpha subunit DUF605 PF04652.11 EEQ74132.1 - 1.2 8.5 23.3 1.4 8.2 16.2 1.1 1 0 0 1 1 1 0 Vta1 like THRAP3_BCLAF1 PF15440.1 EEQ74132.1 - 3.1 6.3 14.9 3.9 6.0 10.3 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF1387 PF07139.6 EEQ74132.1 - 5.7 6.4 5.5 8.2 5.9 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) WD40 PF00400.27 EEQ74133.1 - 8.4e-25 85.7 8.7 5.9e-10 38.6 0.0 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EEQ74133.1 - 2.6e-18 65.6 0.0 6.6e-18 64.3 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nup160 PF11715.3 EEQ74133.1 - 0.0029 15.8 1.8 0.0048 15.0 0.2 1.8 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Pinin_SDK_N PF04697.8 EEQ74133.1 - 0.033 14.2 0.2 0.066 13.2 0.2 1.5 1 0 0 1 1 1 0 pinin/SDK conserved region APH PF01636.18 EEQ74135.1 - 1.6e-07 31.3 1.1 3e-07 30.4 0.8 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ74135.1 - 1.7e-06 27.7 0.0 3.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fungal_trans PF04082.13 EEQ74137.1 - 5.5e-19 68.0 0.0 9.2e-19 67.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EEQ74137.1 - 4.1e-08 33.1 12.5 0.00091 19.4 1.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEQ74137.1 - 1.3e-06 28.4 6.4 1.3e-06 28.4 4.4 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEQ74137.1 - 0.0015 18.7 18.6 0.038 14.3 2.3 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEQ74137.1 - 1.6 8.9 5.4 3.6 7.8 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Trypan_glycop PF00913.14 EEQ74138.1 - 0.033 13.0 2.0 0.058 12.2 1.4 1.3 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) AAA PF00004.24 EEQ74139.1 - 3.5e-08 33.7 0.0 2.8e-06 27.5 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EEQ74139.1 - 5.7e-06 25.2 0.0 5.7e-05 21.9 0.0 2.4 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EEQ74139.1 - 0.0007 20.3 0.0 0.002 18.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEQ74139.1 - 0.008 16.1 0.0 0.029 14.3 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEQ74139.1 - 0.013 15.6 0.0 0.049 13.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EEQ74139.1 - 0.019 14.6 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain TIP49 PF06068.8 EEQ74139.1 - 0.04 12.6 0.0 0.063 11.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 EEQ74139.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 EEQ74139.1 - 0.14 12.0 0.0 0.64 9.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain PX PF00787.19 EEQ74140.1 - 7.2e-17 61.2 0.2 1.4e-16 60.2 0.1 1.4 1 0 0 1 1 1 1 PX domain Prefoldin_3 PF13758.1 EEQ74140.1 - 0.2 11.4 2.5 0.18 11.6 0.2 2.0 2 0 0 2 2 2 0 Prefoldin subunit Nha1_C PF08619.5 EEQ74141.1 - 4.7e-82 276.5 35.1 1.5e-81 274.9 24.3 1.7 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 EEQ74141.1 - 2.1e-66 224.0 21.2 2.4e-66 223.8 14.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EEQ74141.1 - 0.29 11.1 2.0 0.59 10.1 0.5 2.2 2 0 0 2 2 2 0 YrhC-like protein Lipase_GDSL PF00657.17 EEQ74142.1 - 7.3e-06 25.9 0.0 5.5e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SAM_2 PF07647.12 EEQ74143.1 - 2.7e-15 55.9 0.0 4.7e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 EEQ74143.1 - 1.2e-14 54.5 0.0 2.7e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.25 EEQ74143.1 - 1.9e-13 50.3 0.0 3.4e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Atg14 PF10186.4 EEQ74143.1 - 0.018 14.0 0.2 0.041 12.8 0.0 1.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 AAA PF00004.24 EEQ74145.1 - 3.6e-96 318.3 0.0 5.1e-47 159.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EEQ74145.1 - 4.6e-19 68.1 0.7 1.4e-18 66.6 0.5 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EEQ74145.1 - 5.6e-14 52.4 0.0 1.3e-07 31.7 0.0 3.2 3 1 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EEQ74145.1 - 4.2e-13 49.3 0.0 3.1e-06 27.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EEQ74145.1 - 7.8e-13 48.0 0.0 3.3e-05 23.0 0.0 2.9 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EEQ74145.1 - 1.4e-11 45.3 0.0 0.0003 21.5 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EEQ74145.1 - 1.6e-11 44.1 0.4 9.3e-06 25.4 0.0 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEQ74145.1 - 3.9e-11 43.2 0.2 0.0035 17.4 0.0 4.3 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EEQ74145.1 - 5.1e-10 39.6 0.0 0.0018 18.2 0.0 3.9 2 2 1 3 3 3 2 AAA ATPase domain TIP49 PF06068.8 EEQ74145.1 - 6.9e-09 34.9 0.1 0.0012 17.6 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 EEQ74145.1 - 3.9e-08 32.9 0.0 0.005 16.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein CDC48_2 PF02933.12 EEQ74145.1 - 9.8e-08 31.5 0.0 2.8e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.1 EEQ74145.1 - 1.1e-07 31.8 0.0 0.0064 16.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 EEQ74145.1 - 1.8e-07 30.7 1.6 0.0048 16.6 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain AAA_25 PF13481.1 EEQ74145.1 - 1.9e-07 30.7 6.0 0.022 14.1 0.0 4.9 3 2 2 5 5 5 2 AAA domain Zeta_toxin PF06414.7 EEQ74145.1 - 2.6e-07 29.9 0.0 0.0053 15.8 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.16 EEQ74145.1 - 3.4e-07 29.6 0.4 0.028 13.5 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EEQ74145.1 - 1.7e-06 28.1 0.0 0.026 14.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 EEQ74145.1 - 2.9e-06 27.6 0.0 0.051 13.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 EEQ74145.1 - 3e-06 27.1 0.0 0.0056 16.5 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit KaiC PF06745.8 EEQ74145.1 - 4.5e-06 25.9 1.2 0.54 9.3 0.0 3.5 2 1 1 3 3 3 2 KaiC AAA_28 PF13521.1 EEQ74145.1 - 1e-05 25.5 0.0 0.18 11.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 EEQ74145.1 - 4.2e-05 22.8 0.4 0.22 10.6 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.1 EEQ74145.1 - 4.6e-05 23.1 0.3 0.14 11.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.21 EEQ74145.1 - 4.9e-05 22.8 0.1 0.47 9.9 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 EEQ74145.1 - 5.5e-05 23.4 0.0 0.22 11.8 0.0 3.4 2 1 0 2 2 2 1 ABC transporter Sigma54_activ_2 PF14532.1 EEQ74145.1 - 6.4e-05 23.0 0.0 0.36 10.8 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.8 EEQ74145.1 - 6.8e-05 21.9 0.0 0.031 13.2 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 EEQ74145.1 - 8.1e-05 21.6 0.1 0.085 11.7 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 EEQ74145.1 - 0.0003 20.5 0.1 10 5.7 0.0 4.0 2 2 2 4 4 4 0 Archaeal ATPase Vps4_C PF09336.5 EEQ74145.1 - 0.00033 20.4 0.1 0.0017 18.1 0.0 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain Bac_DnaA PF00308.13 EEQ74145.1 - 0.00045 19.9 0.0 1.9 8.0 0.0 3.5 4 0 0 4 4 4 1 Bacterial dnaA protein AAA_3 PF07726.6 EEQ74145.1 - 0.0006 19.4 0.0 1.4 8.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EEQ74145.1 - 0.00064 19.3 0.0 0.95 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EEQ74145.1 - 0.0009 18.9 0.2 0.83 9.2 0.0 3.3 3 0 0 3 3 3 1 NACHT domain DUF2075 PF09848.4 EEQ74145.1 - 0.0013 17.7 0.0 0.6 9.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EEQ74145.1 - 0.0014 18.2 0.0 1.3 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EEQ74145.1 - 0.0029 17.3 0.2 1 9.0 0.0 3.7 3 0 0 3 3 3 1 NTPase NB-ARC PF00931.17 EEQ74145.1 - 0.0033 16.3 0.3 0.6 8.9 0.0 3.1 4 0 0 4 4 4 1 NB-ARC domain Viral_helicase1 PF01443.13 EEQ74145.1 - 0.0067 15.9 0.0 0.55 9.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 EEQ74145.1 - 0.018 14.0 0.0 1.1 8.2 0.0 2.8 2 1 0 3 3 3 0 KAP family P-loop domain T2SE PF00437.15 EEQ74145.1 - 0.02 13.7 0.0 1.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein IPT PF01745.11 EEQ74145.1 - 0.024 13.7 0.1 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_10 PF12846.2 EEQ74145.1 - 0.025 14.0 0.8 10 5.4 0.0 3.7 3 1 1 4 4 4 0 AAA-like domain UPF0079 PF02367.12 EEQ74145.1 - 0.13 11.9 0.1 11 5.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KTI12 PF08433.5 EEQ74145.1 - 0.14 11.3 0.0 19 4.3 0.0 2.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Zot PF05707.7 EEQ74145.1 - 0.16 11.4 0.2 40 3.6 0.1 3.6 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) PEX11 PF05648.9 EEQ74149.1 - 3.9e-14 52.4 0.0 1e-10 41.2 0.0 2.1 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Pilus_PilP PF11356.3 EEQ74149.1 - 0.17 12.1 0.0 0.17 12.1 0.0 2.4 2 0 0 2 2 2 0 Type IV pilus biogenesis Pkinase PF00069.20 EEQ74151.1 - 1.5e-26 93.1 0.0 6.6e-26 91.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ74151.1 - 1.8e-07 30.4 0.0 0.0018 17.3 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Mpv17_PMP22 PF04117.7 EEQ74152.1 - 1.1e-12 47.4 2.2 3.7e-11 42.5 0.3 2.5 3 0 0 3 3 3 2 Mpv17 / PMP22 family UPF0154 PF03672.8 EEQ74152.1 - 0.085 12.4 0.1 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) PCI PF01399.22 EEQ74153.1 - 2.4e-21 76.0 1.0 5e-21 74.9 0.1 2.0 2 1 0 2 2 2 1 PCI domain TPR_7 PF13176.1 EEQ74153.1 - 0.00054 19.5 5.9 0.84 9.5 0.0 5.4 5 1 2 7 7 7 2 Tetratricopeptide repeat DDRGK PF09756.4 EEQ74153.1 - 0.00054 19.4 0.2 0.00094 18.6 0.1 1.3 1 0 0 1 1 1 1 DDRGK domain TPR_8 PF13181.1 EEQ74153.1 - 0.0015 18.1 3.4 22 5.1 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat PCI_Csn8 PF10075.4 EEQ74153.1 - 0.0052 16.5 1.0 0.016 14.9 0.3 2.0 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 TPR_12 PF13424.1 EEQ74153.1 - 0.0059 16.5 13.0 0.44 10.5 0.5 4.9 5 1 0 5 5 5 2 Tetratricopeptide repeat HTH_Crp_2 PF13545.1 EEQ74153.1 - 0.0064 16.2 0.1 0.68 9.7 0.1 3.0 2 1 1 3 3 3 1 Crp-like helix-turn-helix domain UPF0302 PF08864.5 EEQ74153.1 - 0.009 15.8 0.1 0.021 14.6 0.1 1.6 1 0 0 1 1 1 1 UPF0302 domain TPR_2 PF07719.12 EEQ74153.1 - 0.089 12.7 5.8 28 4.9 0.3 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat Prefoldin_2 PF01920.15 EEQ74153.1 - 0.16 11.7 2.4 0.23 11.2 0.5 2.1 2 0 0 2 2 2 0 Prefoldin subunit TPR_16 PF13432.1 EEQ74153.1 - 0.54 11.0 10.3 2.6 8.8 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ74153.1 - 0.55 10.6 0.0 0.55 10.6 0.0 4.9 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ74153.1 - 0.97 9.1 8.3 2.7 7.7 0.1 4.8 6 1 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.27 EEQ74154.1 - 2.1e-35 119.3 5.5 1.9e-08 33.8 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.9 EEQ74154.1 - 1.8e-30 104.7 13.9 3e-30 104.0 9.7 1.4 1 0 0 1 1 1 1 Sof1-like domain adh_short PF00106.20 EEQ74155.1 - 3e-22 79.2 0.0 4.6e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ74155.1 - 8.7e-10 38.7 0.0 1.2e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ74155.1 - 8.4e-07 28.8 0.0 1.4e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EEQ74155.1 - 0.072 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF3950 PF13132.1 EEQ74157.1 - 0.038 13.5 0.2 0.11 12.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3950) PARP PF00644.15 EEQ74158.1 - 6.2e-12 45.3 0.0 1.2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 EEQ74158.1 - 6.4e-08 32.1 0.0 1.9e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EEQ74158.1 - 0.0041 16.9 0.2 0.036 13.9 0.0 2.3 2 0 0 2 2 2 1 RWD domain Prok-E2_B PF14461.1 EEQ74158.1 - 0.076 12.7 0.0 0.37 10.5 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic E2 family B RNA_pol_Rpb4 PF03874.11 EEQ74161.1 - 8.8e-06 25.7 2.7 0.0075 16.2 0.1 2.7 2 1 0 2 2 2 2 RNA polymerase Rpb4 BicD PF09730.4 EEQ74161.1 - 0.053 11.8 0.0 0.08 11.2 0.0 1.2 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Nop PF01798.13 EEQ74162.1 - 1.3e-54 183.5 0.5 3.7e-54 182.0 0.3 1.9 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EEQ74162.1 - 1e-27 95.6 0.1 1.7e-27 94.9 0.1 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EEQ74162.1 - 1.8e-22 79.2 2.0 1.8e-22 79.2 1.4 3.4 3 0 0 3 3 3 1 NOP5NT (NUC127) domain vATP-synt_AC39 PF01992.11 EEQ74163.1 - 2.5e-100 335.9 0.0 3.2e-100 335.5 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit tRNA-synt_1c PF00749.16 EEQ74166.1 - 2.6e-57 193.8 0.0 3.9e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EEQ74166.1 - 0.00071 19.2 0.0 0.0022 17.7 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Rnk_N PF14760.1 EEQ74166.1 - 0.067 13.2 0.2 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Rnk N-terminus RNR_inhib PF08591.5 EEQ74167.1 - 3.6e-19 69.4 0.1 3.6e-19 69.4 0.1 2.0 3 0 0 3 3 3 1 Ribonucleotide reductase inhibitor SDA1 PF05285.7 EEQ74168.1 - 2.5e-93 312.9 33.5 2.5e-93 312.9 23.2 2.3 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 EEQ74168.1 - 1.5e-22 79.6 0.1 3.7e-22 78.3 0.1 1.8 1 0 0 1 1 1 1 NUC130/3NT domain Pkinase PF00069.20 EEQ74169.1 - 1.3e-16 60.4 0.0 3.8e-16 59.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ74169.1 - 0.0011 18.1 0.6 0.56 9.2 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 EEQ74169.1 - 0.017 14.0 0.0 2.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 EEQ74169.1 - 0.038 13.7 0.3 0.038 13.7 0.2 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3853 PF12964.2 EEQ74170.1 - 0.092 12.5 0.0 0.18 11.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3853) Ribosomal_S7 PF00177.16 EEQ74171.1 - 1.8e-39 134.6 1.7 2.3e-39 134.3 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Metallophos PF00149.23 EEQ74172.1 - 1.7e-11 43.8 2.5 2.7e-11 43.2 1.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase APH PF01636.18 EEQ74173.1 - 0.0085 15.8 0.0 0.077 12.7 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family AMP-binding PF00501.23 EEQ74174.1 - 2.1e-56 191.1 0.8 1.1e-24 86.6 0.0 4.8 4 1 0 4 4 4 4 AMP-binding enzyme DMAP_binding PF06464.6 EEQ74174.1 - 2.5e-09 37.6 0.0 8.8e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.7 EEQ74174.1 - 0.0035 17.1 0.8 0.0096 15.7 0.5 1.8 1 0 0 1 1 1 1 Gas vesicle protein G Mpp10 PF04006.7 EEQ74174.1 - 8.1 4.6 6.0 12 4.0 4.2 1.1 1 0 0 1 1 1 0 Mpp10 protein HMGL-like PF00682.14 EEQ74175.1 - 2.1e-67 227.2 0.0 4.5e-67 226.1 0.0 1.6 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EEQ74175.1 - 1.7e-22 79.6 0.0 3.7e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain UPF0146 PF03686.8 EEQ74175.1 - 0.043 13.6 0.1 0.093 12.5 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) DEAD PF00270.24 EEQ74176.1 - 4.5e-45 153.1 0.1 2.6e-44 150.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ74176.1 - 8.4e-27 92.8 0.0 3.2e-26 90.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EEQ74176.1 - 8.1e-07 27.7 0.5 5.2e-06 25.1 0.0 2.4 1 1 2 3 3 3 1 Protein of unknown function (DUF1253) PLRV_ORF5 PF01690.12 EEQ74177.1 - 0.38 9.8 16.8 0.61 9.1 11.7 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF605 PF04652.11 EEQ74177.1 - 9.7 5.4 16.6 13 5.0 11.5 1.1 1 0 0 1 1 1 0 Vta1 like Acetyltransf_3 PF13302.1 EEQ74178.1 - 0.0096 16.0 0.0 0.025 14.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEQ74178.1 - 0.054 13.6 0.0 0.19 11.8 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Arf PF00025.16 EEQ74179.1 - 7.1e-67 224.0 0.6 7.9e-67 223.8 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EEQ74179.1 - 1.5e-12 46.9 3.6 2.2e-07 29.8 0.8 2.7 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EEQ74179.1 - 2.3e-12 46.6 0.0 2.6e-12 46.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EEQ74179.1 - 2.2e-11 43.3 0.0 2.6e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEQ74179.1 - 7.8e-09 35.5 0.0 1.1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEQ74179.1 - 1.9e-08 33.9 0.0 2.4e-06 27.1 0.0 2.0 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Miro PF08477.8 EEQ74179.1 - 2.6e-08 34.3 0.0 3.7e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EEQ74179.1 - 3e-07 29.8 0.0 3.9e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EEQ74179.1 - 0.024 14.1 0.1 0.083 12.3 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 EEQ74179.1 - 0.037 14.8 0.1 0.066 14.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EEQ74179.1 - 0.043 13.1 0.2 0.16 11.2 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.7 EEQ74179.1 - 0.083 12.5 0.1 2.3 7.8 0.0 2.1 2 0 0 2 2 2 0 NACHT domain DUF4045 PF13254.1 EEQ74180.1 - 1.3e-145 485.8 31.0 1.3e-145 485.8 21.5 3.6 3 2 0 3 3 3 1 Domain of unknown function (DUF4045) Gelsolin PF00626.17 EEQ74180.1 - 1.5e-07 31.0 0.1 0.1 12.3 0.0 3.7 3 0 0 3 3 3 3 Gelsolin repeat ALO PF04030.9 EEQ74181.1 - 5.9e-86 288.2 0.0 9.4e-86 287.5 0.0 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EEQ74181.1 - 1e-29 102.7 0.0 1.5e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Zn_clus PF00172.13 EEQ74182.1 - 0.011 15.6 10.8 0.032 14.1 7.5 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-DNL PF05180.7 EEQ74182.1 - 0.015 15.0 0.1 6.4 6.5 0.0 2.5 2 0 0 2 2 2 0 DNL zinc finger Cyt-b5 PF00173.23 EEQ74183.1 - 1.4e-19 69.6 0.1 1.6e-19 69.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Alpha-amyl_C PF09071.5 EEQ74183.1 - 0.003 17.2 0.3 0.12 12.1 0.0 2.3 2 1 0 2 2 2 2 Alpha-amylase, C terminal DUF3712 PF12505.3 EEQ74184.1 - 1.2e-30 106.1 0.0 7.7e-30 103.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) DUF1522 PF07482.6 EEQ74184.1 - 0.04 14.0 0.2 0.081 13.0 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1522) DUF2236 PF09995.4 EEQ74185.1 - 2.3e-55 187.5 0.4 3.1e-55 187.0 0.3 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) HMG_box PF00505.14 EEQ74188.1 - 3e-08 33.8 0.5 3e-08 33.8 0.3 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EEQ74188.1 - 0.00047 20.4 0.3 0.00047 20.4 0.2 2.3 2 0 0 2 2 2 1 HMG-box domain Fungal_trans PF04082.13 EEQ74189.1 - 1.5e-14 53.5 0.4 2.4e-14 52.8 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sec63 PF02889.11 EEQ74190.1 - 2.3e-44 151.9 0.0 6e-43 147.2 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EEQ74190.1 - 8.5e-16 57.4 0.3 2e-15 56.2 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain Peptidase_M24 PF00557.19 EEQ74192.1 - 5e-57 192.8 0.0 7.3e-57 192.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EEQ74192.1 - 4.7e-27 94.0 0.1 1e-26 92.9 0.1 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain SPRY PF00622.23 EEQ74193.1 - 1.2e-18 67.3 0.0 1.9e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 SPRY domain DUF4117 PF13491.1 EEQ74193.1 - 0.038 13.4 0.9 0.056 12.8 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4117) PDEase_II PF02112.10 EEQ74194.1 - 4.8e-53 180.2 0.0 3.3e-45 154.4 0.0 3.0 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EEQ74194.1 - 8.6e-05 22.1 0.0 0.00021 20.9 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EEQ74194.1 - 0.0025 17.5 0.5 0.0089 15.6 0.3 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DXP_redisom_C PF08436.7 EEQ74194.1 - 0.16 11.8 0.0 0.4 10.5 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal Amidase PF01425.16 EEQ74195.1 - 5.9e-82 275.8 0.1 5.9e-82 275.8 0.1 1.5 2 0 0 2 2 2 1 Amidase GWT1 PF06423.7 EEQ74196.1 - 2.3e-44 150.7 0.9 5.7e-44 149.5 0.6 1.7 1 0 0 1 1 1 1 GWT1 Cupin_2 PF07883.6 EEQ74197.1 - 3.1e-06 26.5 0.0 5.3e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EEQ74197.1 - 0.077 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Acyl-CoA_dh_1 PF00441.19 EEQ74198.1 - 3.5e-40 137.5 9.0 5e-40 137.0 6.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EEQ74198.1 - 7.7e-27 94.1 0.2 7.7e-27 94.1 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EEQ74198.1 - 1.1e-17 63.2 0.0 2.1e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EEQ74198.1 - 2.1e-15 57.1 5.2 3.7e-15 56.3 3.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Senescence PF06911.7 EEQ74199.1 - 6.4e-48 162.8 4.4 9.1e-48 162.3 3.1 1.2 1 0 0 1 1 1 1 Senescence-associated protein Ank_2 PF12796.2 EEQ74200.1 - 2.4e-45 152.7 2.9 3.3e-12 46.5 0.0 9.4 9 1 0 9 9 9 7 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEQ74200.1 - 7.4e-34 115.0 4.0 5.3e-05 23.3 0.0 12.9 13 1 1 14 14 14 7 Ankyrin repeats (many copies) Ank PF00023.25 EEQ74200.1 - 9e-34 113.6 2.2 0.00011 21.7 0.0 12.3 12 0 0 12 12 12 6 Ankyrin repeat Ank_4 PF13637.1 EEQ74200.1 - 1.5e-30 105.0 0.7 0.00043 20.7 0.0 11.9 11 1 1 12 12 12 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ74200.1 - 1.1e-24 84.0 1.2 0.077 13.2 0.0 13.6 15 0 0 15 15 15 5 Ankyrin repeat DDT PF02791.12 EEQ74200.1 - 0.12 12.1 0.0 2.2 8.1 0.0 2.8 2 0 0 2 2 2 0 DDT domain Pkinase PF00069.20 EEQ74201.1 - 1.7e-62 210.9 0.0 2.7e-62 210.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ74201.1 - 3.5e-34 118.0 0.0 1.3e-29 103.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEQ74201.1 - 0.00011 21.2 0.0 0.061 12.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EEQ74201.1 - 0.00035 20.3 0.3 0.0034 17.1 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EEQ74201.1 - 0.025 13.9 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF2404 PF10296.4 EEQ74202.1 - 0.0031 17.5 0.0 0.0088 16.1 0.0 1.7 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Rb_C PF08934.5 EEQ74202.1 - 0.088 12.4 0.3 0.19 11.3 0.2 1.5 1 0 0 1 1 1 0 Rb C-terminal domain Bap31 PF05529.7 EEQ74203.1 - 1.2e-68 230.3 0.7 1.4e-68 230.1 0.5 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DivIC PF04977.10 EEQ74203.1 - 0.00021 20.6 0.6 0.04 13.3 0.1 3.3 3 0 0 3 3 3 1 Septum formation initiator TMF_DNA_bd PF12329.3 EEQ74203.1 - 0.00086 19.0 1.8 0.00086 19.0 1.2 1.9 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding Mod_r PF07200.8 EEQ74203.1 - 0.022 14.6 1.1 0.035 14.0 0.7 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.6 EEQ74203.1 - 0.033 12.8 1.5 0.056 12.1 1.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Phage_GP20 PF06810.6 EEQ74203.1 - 0.037 13.4 3.5 0.057 12.8 2.4 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF4349 PF14257.1 EEQ74203.1 - 0.079 12.1 0.5 0.17 11.0 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) DUF192 PF02643.10 EEQ74203.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized ACR, COG1430 DUF1385 PF07136.6 EEQ74203.1 - 2.4 7.1 6.1 5.8 5.9 4.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) Dus PF01207.12 EEQ74204.1 - 2.6e-43 148.0 0.0 9.6e-31 106.7 0.1 2.8 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EEQ74204.1 - 2.1 8.1 4.7 19 5.0 0.3 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2_4 PF13894.1 EEQ74205.1 - 2.3e-05 24.3 10.3 0.062 13.6 0.6 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ74205.1 - 0.00031 20.9 11.7 0.071 13.4 1.0 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EEQ74205.1 - 0.00062 19.8 1.3 0.055 13.6 0.0 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EEQ74205.1 - 0.0016 18.6 10.8 0.017 15.4 0.5 3.1 3 0 0 3 3 3 2 Zinc-finger double domain RNHCP PF12647.2 EEQ74205.1 - 0.053 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 RNHCP domain SprT-like PF10263.4 EEQ74205.1 - 0.085 12.5 0.4 0.14 11.7 0.3 1.3 1 0 0 1 1 1 0 SprT-like family zf-met PF12874.2 EEQ74205.1 - 1.4 9.1 3.9 4.6 7.5 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type TFIIA PF03153.8 EEQ74206.1 - 1.5e-65 222.5 59.1 5.1e-56 191.1 18.8 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit WD40 PF00400.27 EEQ74207.1 - 2.3e-22 77.9 18.1 2.1e-06 27.3 0.1 7.4 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 EEQ74207.1 - 0.00015 21.5 0.4 0.011 15.4 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Kelch_4 PF13418.1 EEQ74208.1 - 1.4e-25 88.7 12.2 2.1e-08 33.8 0.0 5.1 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EEQ74208.1 - 6.2e-23 80.3 4.5 5.8e-06 26.1 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 EEQ74208.1 - 6.2e-22 76.7 4.2 8e-05 22.6 0.1 5.0 4 1 1 5 5 5 4 Kelch motif Kelch_3 PF13415.1 EEQ74208.1 - 4.5e-20 71.2 13.3 2.2e-08 34.0 0.0 6.2 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_2 PF07646.10 EEQ74208.1 - 2.3e-19 68.3 4.5 1.4e-05 24.6 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.20 EEQ74208.1 - 3.9e-17 61.5 5.0 7.9e-05 22.1 0.2 4.6 4 0 0 4 4 4 4 Kelch motif BTB PF00651.26 EEQ74208.1 - 5e-10 39.3 0.1 9.1e-10 38.5 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 EEQ74208.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch Glyco_hydro_1 PF00232.13 EEQ74209.1 - 2.8e-151 503.7 0.0 3.4e-151 503.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF1192 PF06698.6 EEQ74210.1 - 0.062 13.1 4.8 6.7 6.6 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Sel1 PF08238.7 EEQ74211.1 - 3.8e-39 132.2 41.2 3e-06 27.6 0.1 12.7 13 1 0 13 13 13 8 Sel1 repeat DUF1771 PF08590.5 EEQ74211.1 - 0.29 11.1 5.4 0.15 12.1 0.8 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1771) AMP-binding PF00501.23 EEQ74212.1 - 2e-38 131.8 0.1 1.1e-37 129.4 0.1 1.9 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EEQ74212.1 - 9.4e-38 129.5 0.0 1.5e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EEQ74212.1 - 4.3e-10 39.4 0.0 6.4e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EEQ74212.1 - 1.4e-05 25.2 0.0 3.6e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EEQ74212.1 - 0.11 12.3 0.0 0.4 10.5 0.0 2.0 1 1 0 1 1 1 0 short chain dehydrogenase Aldedh PF00171.17 EEQ74214.1 - 2.3e-147 491.0 0.9 2.8e-147 490.7 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EEQ74214.1 - 0.001 17.9 0.8 0.0056 15.4 0.5 2.0 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Pkinase PF00069.20 EEQ74215.1 - 7.8e-10 38.3 0.0 5.5e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ74215.1 - 0.15 11.0 0.3 5.7 5.9 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase WD40 PF00400.27 EEQ74216.1 - 1.8e-15 56.1 4.3 6.3e-05 22.7 0.1 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 EEQ74216.1 - 0.00036 18.8 0.0 0.0011 17.2 0.0 1.6 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Methyltransf_23 PF13489.1 EEQ74217.1 - 3.3e-15 56.1 0.0 6.9e-15 55.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ74217.1 - 1.4e-06 28.8 0.1 4.8e-06 27.1 0.0 1.9 2 1 1 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ74217.1 - 2.6e-06 27.8 0.0 7.4e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEQ74217.1 - 8.1e-05 21.7 0.0 0.00019 20.5 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EEQ74217.1 - 0.00013 22.2 0.0 0.0016 18.7 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ74217.1 - 0.00022 21.6 0.0 0.00095 19.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ74217.1 - 0.00026 20.6 0.0 0.00062 19.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EEQ74217.1 - 0.00028 20.3 0.0 0.00051 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 EEQ74217.1 - 0.0048 16.9 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.15 EEQ74217.1 - 0.0048 16.0 0.0 0.012 14.7 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 EEQ74217.1 - 0.0088 15.2 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_26 PF13659.1 EEQ74217.1 - 0.0089 16.0 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ74217.1 - 0.1 11.7 0.0 1.2 8.2 0.0 2.4 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family WD40 PF00400.27 EEQ74218.1 - 6.6e-15 54.3 8.6 9.2e-08 31.6 0.2 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 EEQ74218.1 - 0.00013 21.7 0.1 0.3 10.7 0.0 2.7 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EEQ74218.1 - 0.017 13.4 0.0 0.04 12.2 0.0 1.5 1 1 0 1 1 1 0 Cytochrome D1 heme domain RNA_pol_Rpb1_1 PF04997.7 EEQ74219.1 - 2.3e-117 392.0 0.0 3.5e-117 391.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EEQ74219.1 - 3.2e-105 351.3 0.1 5.1e-105 350.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EEQ74219.1 - 2.6e-68 229.1 0.0 5.7e-68 228.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EEQ74219.1 - 6.1e-64 215.2 1.4 1.4e-63 214.0 0.9 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EEQ74219.1 - 2.3e-46 157.4 0.0 5.9e-46 156.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EEQ74219.1 - 6.6e-43 145.6 7.8 1.4e-42 144.5 5.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EEQ74219.1 - 6e-37 125.6 0.1 1.3e-36 124.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EEQ74219.1 - 5.8e-10 38.4 194.8 0.031 14.4 7.1 14.6 11 2 3 14 14 14 11 RNA polymerase Rpb1 C-terminal repeat SET PF00856.23 EEQ74222.1 - 6.2e-22 78.6 0.2 6.2e-22 78.6 0.2 3.9 4 3 0 4 4 4 1 SET domain SRI PF08236.6 EEQ74222.1 - 2e-20 72.5 11.7 2e-20 72.5 8.1 2.2 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain Pox_H7 PF04787.7 EEQ74222.1 - 0.4 10.4 6.6 0.39 10.5 3.1 2.0 2 0 0 2 2 2 0 Late protein H7 eIF-6 PF01912.13 EEQ74223.1 - 5.8e-81 270.3 0.1 9.1e-81 269.7 0.1 1.2 1 0 0 1 1 1 1 eIF-6 family DUF3431 PF11913.3 EEQ74224.1 - 1e-71 240.9 0.1 2.8e-71 239.5 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) Pox_A14 PF05767.7 EEQ74226.1 - 0.12 12.3 1.1 0.27 11.2 0.8 1.6 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF3169 PF11368.3 EEQ74226.1 - 0.54 9.4 4.1 2.2 7.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) ABC2_membrane PF01061.19 EEQ74226.1 - 4.1 6.5 10.5 8 5.5 7.3 1.5 1 0 0 1 1 1 0 ABC-2 type transporter DUF3482 PF11981.3 EEQ74228.1 - 0.75 8.9 5.1 1.4 8.0 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) RskA PF10099.4 EEQ74228.1 - 9.7 5.8 14.4 53 3.4 9.4 2.2 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Kelch_6 PF13964.1 EEQ74229.1 - 0.071 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Kelch motif Ku PF02735.11 EEQ74230.1 - 2.2e-36 125.1 0.0 4.4e-36 124.1 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EEQ74230.1 - 5.2e-32 111.0 0.0 7.6e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 EEQ74230.1 - 4e-15 56.1 0.2 1.1e-14 54.6 0.1 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 EEQ74230.1 - 2.9e-12 45.7 0.1 6e-12 44.7 0.1 1.6 1 0 0 1 1 1 1 SAP domain DUF1302 PF06980.6 EEQ74230.1 - 0.041 12.4 0.0 0.059 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) Ferrochelatase PF00762.14 EEQ74231.1 - 8.5e-92 307.4 0.0 1e-91 307.2 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase ADH_zinc_N PF00107.21 EEQ74232.1 - 4.9e-27 94.0 1.0 4.9e-27 94.0 0.7 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEQ74232.1 - 4.6e-17 63.1 0.1 1.2e-16 61.7 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEQ74232.1 - 5.4e-10 39.0 0.0 1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 EEQ74232.1 - 0.011 15.3 0.3 0.035 13.7 0.2 1.8 1 1 1 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.13 EEQ74232.1 - 0.014 15.3 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.16 EEQ74232.1 - 0.078 12.5 0.2 0.16 11.5 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.11 EEQ74233.1 - 1.2e-22 80.1 47.4 5.7e-22 77.9 22.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EEQ74233.1 - 0.0006 18.4 6.6 0.0006 18.4 4.6 3.1 2 1 1 3 3 3 2 Vacuole effluxer Atg22 like PPR_3 PF13812.1 EEQ74234.1 - 9.3e-08 31.7 0.3 5 7.6 0.0 7.7 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR PF01535.15 EEQ74234.1 - 0.093 12.7 0.1 41 4.4 0.0 4.2 4 0 0 4 4 4 0 PPR repeat SE PF08491.5 EEQ74235.1 - 4.2e-95 317.7 0.0 5.2e-95 317.4 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EEQ74235.1 - 4.7e-10 39.0 0.1 2.2e-09 36.8 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEQ74235.1 - 1.5e-07 30.6 0.2 5.7e-07 28.7 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEQ74235.1 - 5.8e-07 28.7 1.3 2.9e-05 23.1 1.2 2.1 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EEQ74235.1 - 6.4e-07 28.5 0.0 8.3e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EEQ74235.1 - 1.6e-05 24.8 0.7 3.3e-05 23.8 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EEQ74235.1 - 6.7e-05 22.1 0.0 0.00014 21.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EEQ74235.1 - 0.00012 22.0 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEQ74235.1 - 0.00023 20.3 0.4 0.00046 19.3 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EEQ74235.1 - 0.00077 18.4 0.4 0.0022 16.9 0.3 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 EEQ74235.1 - 0.001 17.6 0.2 0.0019 16.7 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EEQ74235.1 - 0.0023 18.2 0.2 0.0094 16.3 0.1 2.0 3 0 0 3 3 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EEQ74235.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EEQ74235.1 - 0.012 15.1 0.2 0.02 14.3 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GDI PF00996.13 EEQ74235.1 - 0.045 12.0 0.1 0.068 11.4 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor NAD_Gly3P_dh_N PF01210.18 EEQ74235.1 - 0.052 13.2 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 EEQ74235.1 - 0.094 11.3 0.3 0.41 9.2 0.1 1.9 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 EEQ74235.1 - 0.13 12.3 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PAP_assoc PF03828.14 EEQ74236.1 - 2e-16 59.6 0.0 4.5e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EEQ74236.1 - 7.3e-06 26.2 0.0 1.4e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Exo_endo_phos PF03372.18 EEQ74241.1 - 4.9e-20 72.5 0.1 9.2e-20 71.6 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 EEQ74241.1 - 0.076 12.6 0.1 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 RhoGAP domain DCP1 PF06058.8 EEQ74242.1 - 1.1e-17 64.1 0.0 2.9e-17 62.8 0.0 1.6 1 1 0 1 1 1 1 Dcp1-like decapping family Pex14_N PF04695.8 EEQ74242.1 - 2.3 8.2 9.3 2.8 8.0 0.7 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2305 PF10230.4 EEQ74243.1 - 4.1e-66 223.1 0.0 5.7e-65 219.3 0.0 2.5 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_5 PF12695.2 EEQ74243.1 - 5.3e-07 29.4 0.1 0.00019 21.2 0.0 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ74243.1 - 0.00057 19.8 0.2 0.0023 17.8 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EEQ74243.1 - 0.0053 16.3 0.0 0.026 14.1 0.0 2.0 2 0 0 2 2 2 1 PGAP1-like protein DUF3089 PF11288.3 EEQ74243.1 - 0.019 14.1 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Thioesterase PF00975.15 EEQ74243.1 - 0.051 13.7 0.1 0.13 12.4 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain SMK-1 PF04802.10 EEQ74244.1 - 4.5e-74 248.1 1.0 7.9e-74 247.3 0.7 1.4 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Myb_DNA-bind_6 PF13921.1 EEQ74245.1 - 0.00026 21.0 0.2 0.00041 20.3 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEQ74245.1 - 0.0031 17.5 0.2 0.0051 16.8 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Seryl_tRNA_N PF02403.17 EEQ74246.1 - 0.026 14.5 9.0 0.66 10.0 2.9 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Mlp PF03304.8 EEQ74246.1 - 0.075 13.0 2.7 4.8 7.1 0.6 2.0 2 0 0 2 2 2 0 Mlp lipoprotein family Lge1 PF11488.3 EEQ74246.1 - 0.13 12.4 5.3 0.75 10.0 1.4 2.2 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 OmpH PF03938.9 EEQ74246.1 - 0.14 12.0 8.4 0.18 11.7 5.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Spectrin PF00435.16 EEQ74246.1 - 0.2 11.9 5.7 0.28 11.5 3.4 1.6 1 1 0 1 1 1 0 Spectrin repeat Prefoldin_2 PF01920.15 EEQ74246.1 - 0.24 11.1 7.4 0.77 9.5 2.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit Prominin PF05478.6 EEQ74246.1 - 0.26 8.7 1.7 0.29 8.5 1.2 1.2 1 0 0 1 1 1 0 Prominin DUF724 PF05266.9 EEQ74246.1 - 0.31 10.6 5.3 0.48 10.0 3.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) GreA_GreB_N PF03449.10 EEQ74246.1 - 0.41 10.7 3.9 1.7 8.7 0.9 2.2 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Exonuc_VII_L PF02601.10 EEQ74246.1 - 0.45 9.6 3.4 0.47 9.5 2.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit PKK PF12474.3 EEQ74246.1 - 0.51 10.0 7.9 0.097 12.3 2.4 1.8 2 0 0 2 2 2 0 Polo kinase kinase DivIC PF04977.10 EEQ74246.1 - 0.59 9.6 12.2 0.77 9.2 2.8 2.4 1 1 1 2 2 2 0 Septum formation initiator BLOC1_2 PF10046.4 EEQ74246.1 - 0.68 10.1 8.2 2.6 8.2 1.8 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Gon7 PF08738.5 EEQ74246.1 - 0.75 9.8 3.1 0.51 10.3 0.9 1.6 2 0 0 2 2 2 0 Gon7 family IncA PF04156.9 EEQ74246.1 - 0.78 9.2 12.1 1.2 8.6 8.4 1.3 1 1 0 1 1 1 0 IncA protein DUF2205 PF10224.4 EEQ74246.1 - 0.87 9.2 6.5 1.1 8.8 1.3 2.3 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) TMF_DNA_bd PF12329.3 EEQ74246.1 - 0.88 9.4 10.7 0.94 9.3 4.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 EEQ74246.1 - 0.95 8.4 8.5 1 8.3 5.9 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_23 PF13476.1 EEQ74246.1 - 1.2 9.4 9.5 1.8 8.8 6.6 1.2 1 0 0 1 1 1 0 AAA domain Mnd1 PF03962.10 EEQ74246.1 - 1.2 8.7 5.8 2 8.0 4.0 1.3 1 1 0 1 1 1 0 Mnd1 family Med4 PF10018.4 EEQ74246.1 - 1.3 8.3 9.4 0.56 9.5 3.8 1.9 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Syntaxin-6_N PF09177.6 EEQ74246.1 - 1.4 9.4 5.4 7.7 6.9 3.7 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Tup_N PF08581.5 EEQ74246.1 - 1.7 8.9 9.4 4.2 7.6 2.3 2.3 1 1 0 2 2 2 0 Tup N-terminal Tropomyosin_1 PF12718.2 EEQ74246.1 - 2 8.2 11.3 21 4.9 7.9 1.9 1 1 0 1 1 1 0 Tropomyosin like DUF1664 PF07889.7 EEQ74246.1 - 2.1 8.1 4.8 5 6.9 1.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Atg14 PF10186.4 EEQ74246.1 - 2.6 6.8 6.4 2.9 6.7 4.4 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4200 PF13863.1 EEQ74246.1 - 3 7.8 11.6 41 4.1 8.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF342 PF03961.8 EEQ74246.1 - 3.9 5.7 6.8 4.5 5.5 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4140 PF13600.1 EEQ74246.1 - 6.1 7.3 9.9 3.5 8.1 0.3 2.2 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) APH PF01636.18 EEQ74247.1 - 1.4e-14 54.3 0.0 1.9e-13 50.7 0.0 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ74247.1 - 0.00038 20.1 0.2 0.0014 18.1 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 EEQ74247.1 - 0.042 12.8 0.0 0.12 11.3 0.0 1.7 1 1 0 1 1 1 0 Fructosamine kinase zf-C3HC4 PF00097.20 EEQ74249.1 - 4.5e-05 23.0 7.2 6.8e-05 22.4 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ74249.1 - 7.5e-05 22.3 5.8 0.00013 21.5 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ74249.1 - 0.00039 20.1 7.1 0.001 18.7 5.0 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEQ74249.1 - 0.00044 20.2 10.5 0.00067 19.6 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ74249.1 - 0.00078 19.2 10.5 0.0013 18.4 7.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EEQ74249.1 - 0.0034 17.0 1.8 0.0072 16.0 1.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EEQ74249.1 - 0.053 13.4 6.3 0.1 12.4 4.4 1.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EEQ74249.1 - 0.96 9.2 5.3 1.6 8.5 3.7 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EEQ74249.1 - 6.3 6.7 9.3 3.1 7.6 4.4 2.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF914 PF06027.7 EEQ74250.1 - 6e-105 350.7 16.5 7.8e-105 350.4 11.5 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EEQ74250.1 - 2.7e-05 24.2 28.8 0.00014 21.9 7.7 2.5 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 EEQ74250.1 - 0.0017 18.0 3.9 0.0017 18.0 2.7 2.8 3 0 0 3 3 3 1 Triose-phosphate Transporter family STE3 PF02076.10 EEQ74253.1 - 9.9e-97 323.4 14.0 1.2e-96 323.1 9.7 1.0 1 0 0 1 1 1 1 Pheromone A receptor Pex24p PF06398.6 EEQ74253.1 - 3.1 6.5 9.8 0.084 11.6 2.1 1.8 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin SSB PF00436.20 EEQ74254.1 - 1.7e-16 59.9 0.0 2.1e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF4203 PF13886.1 EEQ74256.1 - 1.8e-35 122.3 9.3 2.5e-35 121.8 6.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Erf4 PF10256.4 EEQ74258.1 - 1.3e-32 112.1 0.0 1.9e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Adap_comp_sub PF00928.16 EEQ74259.1 - 1.2e-78 263.8 0.0 1.6e-78 263.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EEQ74259.1 - 0.0001 22.0 0.2 0.00019 21.1 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 EEQ74259.1 - 0.07 12.3 0.1 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain zf-CCHC PF00098.18 EEQ74260.1 - 0.044 13.7 1.3 0.098 12.6 0.9 1.6 1 0 0 1 1 1 0 Zinc knuckle APH PF01636.18 EEQ74266.1 - 1.1e-13 51.4 0.2 1.2e-12 48.1 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ74266.1 - 0.14 11.7 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 EEQ74270.1 - 4.3e-59 199.7 0.0 6.3e-58 195.9 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ74270.1 - 1.4e-30 106.1 0.0 7.4e-29 100.5 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 EEQ74270.1 - 2.4e-06 26.7 0.0 6.7e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEQ74270.1 - 0.00065 18.7 0.0 0.0011 17.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EEQ74270.1 - 0.005 16.2 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 EEQ74270.1 - 0.0054 16.4 0.5 0.0054 16.4 0.4 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EEQ74270.1 - 0.029 13.1 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ank_5 PF13857.1 EEQ74271.1 - 0.0005 20.2 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EEQ74271.1 - 0.00082 19.0 0.3 0.002 17.8 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.1 EEQ74271.1 - 0.0015 18.6 0.0 0.0049 16.9 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 EEQ74271.1 - 0.017 15.4 0.0 0.058 13.7 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) zf-C2H2_2 PF12756.2 EEQ74271.1 - 0.054 13.6 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) ABC_membrane PF00664.18 EEQ74272.1 - 1e-79 267.8 31.0 5.4e-44 150.6 6.0 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEQ74272.1 - 2.3e-51 173.7 0.0 7.1e-30 104.0 0.0 3.3 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.14 EEQ74272.1 - 9e-10 38.1 3.0 0.00094 18.4 0.1 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EEQ74272.1 - 2.5e-06 27.5 1.5 0.0057 16.6 0.7 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EEQ74272.1 - 4.8e-05 22.8 0.1 0.24 10.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EEQ74272.1 - 5.3e-05 23.1 0.5 0.52 10.2 0.1 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EEQ74272.1 - 0.00011 21.5 0.1 0.27 10.7 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EEQ74272.1 - 0.00017 21.6 4.2 0.74 9.7 0.0 4.3 4 0 0 4 4 3 1 AAA domain DUF258 PF03193.11 EEQ74272.1 - 0.00023 20.4 0.2 0.078 12.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EEQ74272.1 - 0.00065 20.0 1.0 0.052 13.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain Miro PF08477.8 EEQ74272.1 - 0.00071 20.0 0.8 1.1 9.8 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 EEQ74272.1 - 0.002 17.9 0.4 0.31 10.8 0.0 2.7 2 0 0 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.13 EEQ74272.1 - 0.0026 17.2 0.0 0.73 9.2 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_30 PF13604.1 EEQ74272.1 - 0.018 14.6 4.2 1.3 8.5 0.0 4.2 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.17 EEQ74272.1 - 0.072 13.2 0.1 7.6 6.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 EEQ74272.1 - 0.11 11.6 0.1 15 4.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.12 EEQ74272.1 - 1.4 8.6 7.4 2.4 7.9 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_22 PF13401.1 EEQ74272.1 - 1.7 8.7 4.6 15 5.6 0.0 3.5 4 0 0 4 4 4 0 AAA domain DUF2841 PF11001.3 EEQ74276.1 - 3.7e-47 159.3 0.8 5.5e-47 158.7 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) CTP_synth_N PF06418.9 EEQ74277.1 - 1.8e-116 388.0 0.4 2.6e-116 387.5 0.3 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EEQ74277.1 - 6e-58 195.4 0.0 1.2e-57 194.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EEQ74277.1 - 1.9e-08 34.0 0.1 6.5e-08 32.2 0.0 1.9 3 0 0 3 3 3 1 Peptidase C26 CbiA PF01656.18 EEQ74277.1 - 0.00052 19.4 0.0 0.0012 18.2 0.0 1.6 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Methyltransf_24 PF13578.1 EEQ74277.1 - 0.012 16.4 0.1 0.036 14.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain ArsA_ATPase PF02374.10 EEQ74277.1 - 0.16 10.9 0.3 0.29 10.1 0.2 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase Zip PF02535.17 EEQ74278.1 - 6.7e-50 169.8 0.1 1.1e-49 169.1 0.0 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter DUF1700 PF08006.6 EEQ74278.1 - 0.28 10.4 0.0 0.28 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) SAC3_GANP PF03399.11 EEQ74279.1 - 9.7e-57 191.8 2.2 1.4e-56 191.3 1.5 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EEQ74279.1 - 7.2e-06 25.8 0.1 2e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 DUF3435 PF11917.3 EEQ74280.1 - 1.3e-10 40.6 0.0 4.2e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) CN_hydrolase PF00795.17 EEQ74282.1 - 2.4e-08 33.5 0.0 0.015 14.6 0.0 3.1 3 0 0 3 3 3 3 Carbon-nitrogen hydrolase HLH PF00010.21 EEQ74283.1 - 1.9e-12 46.6 0.9 3.7e-12 45.7 0.6 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sox_C_TAD PF12067.3 EEQ74283.1 - 0.028 14.6 1.3 0.051 13.7 0.9 1.4 1 0 0 1 1 1 0 Sox C-terminal transactivation domain Sec8_exocyst PF04048.9 EEQ74284.1 - 2.3e-47 160.1 2.7 2.5e-47 160.0 0.1 2.4 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EEQ74284.1 - 4.3e-08 32.3 0.2 9.5e-08 31.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Zw10 PF06248.8 EEQ74284.1 - 0.0073 14.5 1.0 0.02 13.0 0.1 1.9 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Peptidase_M24 PF00557.19 EEQ74285.1 - 4.7e-40 137.3 0.1 6.4e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EEQ74285.1 - 1.9e-23 83.4 0.0 4.1e-21 75.8 0.0 2.7 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain IBN_N PF03810.14 EEQ74286.1 - 0.018 14.9 0.1 0.05 13.5 0.0 1.8 1 0 0 1 1 1 0 Importin-beta N-terminal domain SOR_SNZ PF01680.12 EEQ74287.1 - 1.2e-109 364.7 5.6 1.2e-109 364.7 3.9 1.5 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.9 EEQ74287.1 - 5.4e-11 42.0 3.9 9.3e-08 31.4 0.0 2.6 2 1 0 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 EEQ74287.1 - 0.00046 19.1 0.7 0.21 10.3 0.0 2.3 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EEQ74287.1 - 0.0014 17.9 0.4 0.14 11.3 0.1 3.0 2 1 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.16 EEQ74287.1 - 0.0014 17.7 0.0 0.016 14.2 0.0 2.3 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.9 EEQ74287.1 - 0.002 17.1 0.4 0.091 11.7 0.0 2.5 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.10 EEQ74287.1 - 0.017 14.3 5.5 0.017 14.2 0.1 2.4 2 1 0 2 2 2 0 Nitronate monooxygenase FUN14 PF04930.10 EEQ74288.1 - 1.3e-10 41.4 1.1 3.5e-10 40.0 0.8 1.8 1 1 0 1 1 1 1 FUN14 family ORC2 PF04084.9 EEQ74289.1 - 1.1e-101 339.9 0.0 1.4e-101 339.6 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 EAL PF00563.15 EEQ74289.1 - 0.095 12.1 0.0 0.39 10.1 0.0 1.9 2 0 0 2 2 2 0 EAL domain MSP1_C PF07462.6 EEQ74289.1 - 0.16 10.3 2.4 0.23 9.7 1.7 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus PPP4R2 PF09184.6 EEQ74289.1 - 4.8 6.6 10.0 9.9 5.6 7.0 1.4 1 0 0 1 1 1 0 PPP4R2 ArgJ PF01960.13 EEQ74290.1 - 9.7e-146 485.1 0.1 1.1e-145 484.9 0.1 1.0 1 0 0 1 1 1 1 ArgJ family SecY PF00344.15 EEQ74291.1 - 4.7e-97 325.0 7.3 5.9e-97 324.6 5.1 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EEQ74291.1 - 2.6e-18 65.2 0.3 7.8e-18 63.6 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p TPR_MLP1_2 PF07926.7 EEQ74292.1 - 0.01 15.6 15.6 0.01 15.6 10.8 4.5 2 2 2 4 4 4 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EEQ74292.1 - 0.02 14.1 0.7 0.32 10.1 0.7 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein ubiquitin PF00240.18 EEQ74292.1 - 0.31 10.4 2.7 3.2 7.2 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin family DUF3584 PF12128.3 EEQ74292.1 - 4 4.6 47.6 40 1.3 33.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4140 PF13600.1 EEQ74292.1 - 5.6 7.4 25.3 2.7 8.4 0.5 5.4 3 1 2 5 5 5 0 N-terminal domain of unknown function (DUF4140) SUR7 PF06687.7 EEQ74293.1 - 9.4 5.7 9.5 12 5.4 6.6 1.1 1 0 0 1 1 1 0 SUR7/PalI family GFA PF04828.9 EEQ74294.1 - 1.4e-12 47.3 3.5 8.2e-12 44.9 2.4 2.0 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme MFS_1 PF07690.11 EEQ74295.1 - 2.1e-26 92.4 53.5 7.6e-24 84.0 28.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ74295.1 - 6.1e-05 21.7 44.7 0.00053 18.6 14.2 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter MUG113 PF13455.1 EEQ74296.1 - 1.4e-32 111.9 1.1 2.6e-32 111.1 0.7 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EEQ74296.1 - 5e-24 84.6 0.3 1.4e-23 83.1 0.2 1.7 1 0 0 1 1 1 1 T5orf172 domain ABC_membrane PF00664.18 EEQ74297.1 - 1.4e-92 310.0 42.0 1.7e-46 158.9 12.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEQ74297.1 - 8.7e-67 223.6 0.0 1.9e-32 112.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EEQ74297.1 - 7.1e-15 54.8 0.1 3.1e-06 26.5 0.0 3.3 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEQ74297.1 - 2.9e-10 40.5 0.1 0.04 13.8 0.0 4.4 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EEQ74297.1 - 1.5e-08 34.0 0.5 0.00048 19.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EEQ74297.1 - 8.5e-08 31.1 1.0 0.0029 16.2 0.1 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 EEQ74297.1 - 3.1e-07 30.5 1.6 0.0027 17.7 0.0 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EEQ74297.1 - 3.2e-07 31.2 0.1 0.042 14.6 0.0 3.2 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 EEQ74297.1 - 1.2e-06 27.8 0.0 0.08 12.1 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EEQ74297.1 - 8e-06 25.3 2.4 0.084 12.2 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EEQ74297.1 - 4.6e-05 23.5 0.9 0.43 10.7 0.0 3.6 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EEQ74297.1 - 0.00021 20.4 0.0 0.28 10.2 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA PF00004.24 EEQ74297.1 - 0.0003 20.9 2.0 13 5.9 0.0 4.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEQ74297.1 - 0.00053 19.7 0.4 0.92 9.2 0.0 3.6 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EEQ74297.1 - 0.00071 19.4 0.4 0.91 9.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.1 EEQ74297.1 - 0.0014 18.4 5.6 0.61 10.0 0.2 4.2 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 EEQ74297.1 - 0.0024 17.7 0.0 3 7.7 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.1 EEQ74297.1 - 0.0028 17.9 0.0 4.9 7.4 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EEQ74297.1 - 0.0031 16.9 1.5 2.3 7.5 0.2 3.7 4 0 0 4 4 4 1 AAA-like domain AAA_30 PF13604.1 EEQ74297.1 - 0.0043 16.6 5.1 4.3 6.8 0.2 4.0 3 1 0 3 3 3 1 AAA domain SRP54 PF00448.17 EEQ74297.1 - 0.011 15.2 0.4 1.6 8.1 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.1 EEQ74297.1 - 0.013 15.4 1.6 0.66 9.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 EEQ74297.1 - 0.017 15.2 0.0 6.5 6.9 0.0 2.9 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 EEQ74297.1 - 0.017 14.7 0.3 6.8 6.4 0.0 2.9 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 EEQ74297.1 - 0.02 13.6 0.0 3.9 6.0 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit DUF87 PF01935.12 EEQ74297.1 - 0.023 14.4 0.1 8.2 6.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 PRK PF00485.13 EEQ74297.1 - 0.06 12.9 0.0 11 5.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.1 EEQ74297.1 - 0.082 13.2 0.7 5.7 7.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.10 EEQ74297.1 - 0.13 10.9 0.1 2.3 6.8 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Ribosomal_L39 PF00832.15 EEQ74299.1 - 1.4e-12 46.8 2.8 2.1e-12 46.2 1.9 1.3 1 0 0 1 1 1 1 Ribosomal L39 protein Skp1 PF01466.14 EEQ74300.1 - 1e-38 131.1 2.2 1.5e-38 130.6 1.5 1.2 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EEQ74300.1 - 2e-14 53.4 0.0 4.5e-14 52.2 0.0 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 EEQ74300.1 - 0.089 12.7 0.1 0.17 11.8 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4375) Glyco_transf_22 PF03901.12 EEQ74301.1 - 1.5e-48 165.8 18.1 2.3e-24 86.2 4.4 2.2 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family p450 PF00067.17 EEQ74302.1 - 1.4e-62 211.7 0.0 1.9e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sybindin PF04099.7 EEQ74303.1 - 1.7e-25 89.3 0.0 2.3e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EEQ74303.1 - 0.0014 18.5 0.1 0.0027 17.5 0.1 1.4 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase PF00069.20 EEQ74304.1 - 3.6e-54 183.6 0.0 2e-53 181.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ74304.1 - 6.7e-35 120.3 0.0 1.3e-33 116.2 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ74304.1 - 5.8e-09 35.3 0.0 1.4e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEQ74304.1 - 0.0098 15.6 0.3 0.026 14.2 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pept_tRNA_hydro PF01195.14 EEQ74305.1 - 3.6e-20 72.2 0.0 1.2e-06 28.1 0.0 3.5 3 1 0 3 3 3 3 Peptidyl-tRNA hydrolase Methyltransf_23 PF13489.1 EEQ74308.1 - 4.7e-15 55.6 0.0 1.4e-14 54.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ74308.1 - 3.1e-08 33.3 0.0 1.9e-07 30.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ74308.1 - 1.2e-06 29.0 0.1 7.6e-06 26.4 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ74308.1 - 0.0001 22.7 0.0 0.00077 19.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEQ74308.1 - 0.0048 15.9 0.0 0.0081 15.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EEQ74308.1 - 0.077 12.3 0.0 0.18 11.1 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain PhyH PF05721.8 EEQ74309.1 - 1.3e-09 38.4 0.0 2.2e-08 34.3 0.0 2.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Cupin_2 PF07883.6 EEQ74309.1 - 0.079 12.4 0.0 0.25 10.8 0.0 1.8 1 0 0 1 1 1 0 Cupin domain Brix PF04427.13 EEQ74310.1 - 1.6e-39 135.5 0.2 2.3e-39 135.0 0.1 1.2 1 0 0 1 1 1 1 Brix domain BUD22 PF09073.5 EEQ74310.1 - 0.0056 15.8 17.3 0.0087 15.1 12.0 1.2 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.7 EEQ74310.1 - 3.8 5.3 25.5 5.1 4.8 17.7 1.1 1 0 0 1 1 1 0 Nop14-like family tRNA-synt_2b PF00587.20 EEQ74311.1 - 6e-67 224.5 0.2 9e-67 223.9 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEQ74311.1 - 1.1e-19 70.1 3.2 1.5e-19 69.6 0.0 2.9 3 1 0 3 3 3 1 Anticodon binding domain Pkinase PF00069.20 EEQ74313.1 - 6.5e-70 235.2 0.1 1.2e-69 234.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ74313.1 - 1.2e-51 175.2 0.0 2.2e-51 174.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH_11 PF15413.1 EEQ74313.1 - 6.2e-28 97.3 0.5 1.6e-27 96.0 0.3 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PBD PF00786.23 EEQ74313.1 - 3.1e-22 78.7 0.2 3.1e-21 75.5 0.0 2.8 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 EEQ74313.1 - 8e-07 28.3 0.0 1.9e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like PH PF00169.24 EEQ74313.1 - 6.3e-06 26.3 0.2 1.3e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 PH domain APH PF01636.18 EEQ74313.1 - 0.00081 19.1 3.0 0.0063 16.2 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EEQ74313.1 - 0.028 13.2 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 NAD_kinase PF01513.16 EEQ74314.1 - 1.1e-49 168.7 0.0 1.7e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Acyltransferase PF01553.16 EEQ74315.1 - 1.5e-27 95.6 0.0 2.3e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase TPR_11 PF13414.1 EEQ74316.1 - 3e-24 84.4 27.9 6.3e-06 25.7 0.0 10.2 9 3 3 12 12 12 6 TPR repeat TPR_2 PF07719.12 EEQ74316.1 - 2.3e-22 77.0 26.9 0.0056 16.5 0.1 11.9 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ74316.1 - 3.1e-19 69.0 21.3 4.7e-06 26.8 0.2 9.1 8 2 2 10 10 9 6 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ74316.1 - 6.2e-19 66.7 20.6 0.00071 19.0 0.0 10.2 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ74316.1 - 4.2e-17 61.8 27.5 1.8e-05 24.5 0.6 10.1 10 1 0 11 11 11 3 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ74316.1 - 4.5e-17 61.0 23.3 0.0092 16.5 0.0 11.3 10 3 2 12 12 11 4 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ74316.1 - 2.1e-14 53.7 30.5 8.7e-05 23.0 0.0 10.3 11 1 1 12 12 12 4 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ74316.1 - 7.2e-13 47.3 25.0 0.0014 18.2 0.1 11.0 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ74316.1 - 5.3e-11 42.2 23.7 0.15 12.5 0.1 11.5 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ74316.1 - 6e-08 31.9 20.1 0.0065 16.1 0.1 8.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ74316.1 - 4.4e-05 23.3 19.3 0.044 13.9 0.0 10.2 13 0 0 13 13 11 1 Tetratricopeptide repeat Apc3 PF12895.2 EEQ74316.1 - 0.00049 20.1 18.1 0.59 10.3 0.2 7.1 5 3 2 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 EEQ74316.1 - 0.0062 16.3 4.6 4.6 7.1 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat SGL PF08450.7 EEQ74317.1 - 2.3e-28 99.2 0.1 1.5e-14 53.9 0.0 2.3 2 0 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EEQ74317.1 - 0.055 13.4 0.3 0.58 10.1 0.0 2.8 3 0 0 3 3 3 0 Arylesterase Fungal_trans_2 PF11951.3 EEQ74318.1 - 9e-05 21.2 0.6 0.00016 20.3 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.23 EEQ74319.1 - 0.00063 18.5 0.1 0.00088 18.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family DUF2807 PF10988.3 EEQ74323.1 - 1.9 7.9 7.0 1.7 8.1 4.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2807) Nucleoplasmin PF03066.10 EEQ74324.1 - 0.034 13.6 2.5 0.11 12.0 2.0 1.6 2 0 0 2 2 2 0 Nucleoplasmin RXT2_N PF08595.6 EEQ74324.1 - 0.22 11.3 3.5 0.4 10.4 2.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Es2 PF09751.4 EEQ74326.1 - 5.7e-101 338.9 0.3 5.3e-79 266.5 0.0 2.1 1 1 1 2 2 2 2 Nuclear protein Es2 DUF1675 PF07897.6 EEQ74326.1 - 0.19 11.5 3.6 0.33 10.7 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Mcm10 PF09332.6 EEQ74326.1 - 2 7.7 4.9 24 4.1 2.6 2.3 1 1 0 2 2 2 0 Mcm10 replication factor Mid1 PF12929.2 EEQ74327.1 - 1e-146 489.0 1.2 1.2e-146 488.8 0.9 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 EEQ74327.1 - 0.079 13.3 3.0 1.3 9.3 0.2 2.4 2 0 0 2 2 2 0 Fz domain Ost4 PF10215.4 EEQ74327.1 - 0.53 9.8 2.8 0.4 10.2 0.3 1.9 2 0 0 2 2 2 0 Oligosaccaryltransferase Kin17_mid PF10357.4 EEQ74328.1 - 1.2e-51 173.6 0.3 1.2e-51 173.6 0.2 1.6 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 EEQ74328.1 - 0.00051 20.1 1.6 0.00096 19.2 1.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEQ74328.1 - 0.00052 20.1 2.5 0.001 19.2 1.8 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EEQ74328.1 - 0.0062 16.6 2.4 0.0081 16.2 0.1 2.0 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Hamartin PF04388.7 EEQ74328.1 - 0.0077 14.9 9.5 0.01 14.5 6.6 1.3 1 0 0 1 1 1 1 Hamartin protein SerH PF06873.6 EEQ74328.1 - 0.13 10.8 5.7 0.21 10.1 4.0 1.3 1 0 0 1 1 1 0 Cell surface immobilisation antigen SerH CorA PF01544.13 EEQ74329.1 - 9.4e-42 143.0 0.1 1.8e-41 142.1 0.0 1.4 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein SPC12 PF06645.8 EEQ74333.1 - 1e-27 95.7 0.2 1.3e-27 95.4 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MerC PF03203.9 EEQ74333.1 - 0.039 14.3 0.2 0.041 14.2 0.2 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein zf-rbx1 PF12678.2 EEQ74334.1 - 1.3e-35 121.3 12.9 1.7e-35 120.9 8.9 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EEQ74334.1 - 4.3e-17 61.7 9.8 5.7e-17 61.3 6.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EEQ74334.1 - 2.9e-07 30.2 12.6 1.7e-06 27.7 8.7 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EEQ74334.1 - 0.0019 17.8 11.3 0.032 13.9 7.9 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ74334.1 - 0.0048 16.5 9.8 0.36 10.5 6.8 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ74334.1 - 0.049 13.6 13.0 0.053 13.5 5.9 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EEQ74334.1 - 0.12 12.3 8.9 0.5 10.3 6.3 1.8 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 EEQ74334.1 - 1.1 9.3 10.2 2.8 7.9 7.0 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EEQ74334.1 - 1.4 9.1 10.5 63 3.8 7.3 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_UBOX PF13445.1 EEQ74334.1 - 1.8 8.3 6.3 39 4.0 4.4 2.3 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 EEQ74334.1 - 2.1 8.1 11.4 15 5.4 7.9 2.3 1 1 0 1 1 1 0 zinc-RING finger domain PNRC PF15365.1 EEQ74335.1 - 9e-07 28.8 2.6 9e-07 28.8 1.8 4.8 6 0 0 6 6 6 2 Proline-rich nuclear receptor coactivator SMI1_KNR4 PF09346.5 EEQ74336.1 - 1.1e-35 122.5 0.0 1.6e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Thioredoxin PF00085.15 EEQ74337.1 - 0.085 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin DUF2547 PF10818.3 EEQ74337.1 - 0.098 13.2 5.2 0.16 12.6 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) APC_CDC26 PF10471.4 EEQ74337.1 - 0.12 13.0 7.1 0.22 12.2 4.9 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF2802 PF10975.3 EEQ74337.1 - 8.2 6.2 10.2 16 5.3 7.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) Methyltransf_11 PF08241.7 EEQ74338.1 - 3.3e-11 43.5 0.0 5.6e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ74338.1 - 2.4e-07 30.5 0.0 3.9e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ74338.1 - 2.9e-05 24.4 0.0 0.0005 20.5 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ74338.1 - 0.00069 19.2 0.0 0.0027 17.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ74338.1 - 0.019 15.5 0.0 0.42 11.2 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ74338.1 - 0.041 14.2 0.0 0.1 12.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Synaptobrevin PF00957.16 EEQ74339.1 - 2e-33 113.8 1.1 2.3e-33 113.6 0.8 1.0 1 0 0 1 1 1 1 Synaptobrevin GP41 PF00517.12 EEQ74339.1 - 0.092 12.2 0.1 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein DUF619 PF04768.8 EEQ74340.1 - 6.5e-51 172.1 0.1 1.3e-50 171.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EEQ74340.1 - 7.2e-29 100.5 0.0 2.7e-28 98.6 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EEQ74340.1 - 1.4e-23 83.7 0.0 3.1e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 Amino acid kinase family T4_gp9_10 PF07880.6 EEQ74340.1 - 0.0093 15.0 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 Bacteriophage T4 gp9/10-like protein DapB_N PF01113.15 EEQ74340.1 - 0.027 14.3 0.0 0.08 12.8 0.0 1.9 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 EEQ74340.1 - 0.11 13.0 0.0 0.33 11.4 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Rad21_Rec8_N PF04825.8 EEQ74341.1 - 2.6e-23 82.0 0.1 9e-23 80.3 0.0 1.9 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EEQ74341.1 - 0.012 14.8 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein adh_short PF00106.20 EEQ74342.1 - 2.6e-27 95.7 0.7 3.5e-27 95.3 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ74342.1 - 9.6e-18 64.8 0.0 1.3e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ74342.1 - 3e-10 40.0 0.5 5e-10 39.3 0.3 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EEQ74342.1 - 8.5e-06 25.5 0.1 1.5e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EEQ74342.1 - 0.0011 18.4 0.1 0.0017 17.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EEQ74342.1 - 0.0097 14.8 0.1 0.014 14.2 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EEQ74342.1 - 0.016 15.0 1.3 0.35 10.7 0.2 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Saccharop_dh PF03435.13 EEQ74342.1 - 0.019 13.9 0.2 0.034 13.1 0.1 1.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase Methyltransf_18 PF12847.2 EEQ74342.1 - 0.023 15.2 0.0 0.1 13.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain NAD_binding_10 PF13460.1 EEQ74342.1 - 0.026 14.5 1.3 0.094 12.7 0.7 2.0 1 1 0 1 1 1 0 NADH(P)-binding Methyltransf_12 PF08242.7 EEQ74342.1 - 0.072 13.5 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain THF_DHG_CYH_C PF02882.14 EEQ74342.1 - 0.077 12.0 0.2 0.18 10.8 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Gln-synt_C PF00120.19 EEQ74343.1 - 6.3e-59 199.2 0.0 8e-59 198.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain DUF3237 PF11578.3 EEQ74346.1 - 2e-36 124.5 0.0 3e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.10 EEQ74346.1 - 2.5e-07 30.3 2.9 0.007 16.0 0.3 2.4 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_2 PF12756.2 EEQ74346.1 - 0.2 11.7 7.2 3.8 7.6 0.4 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) PAT1 PF09770.4 EEQ74346.1 - 0.87 7.7 12.1 1.1 7.3 8.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AdoMet_MTase PF07757.8 EEQ74347.1 - 5.6e-33 113.4 0.0 2.4e-32 111.3 0.0 2.0 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase SMC_N PF02463.14 EEQ74348.1 - 2e-22 79.4 0.0 1.3e-21 76.8 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EEQ74348.1 - 3.8e-18 66.5 0.3 3.8e-18 66.5 0.2 5.5 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.1 EEQ74348.1 - 2.4e-06 27.7 0.1 0.0012 18.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EEQ74348.1 - 0.0024 17.3 0.0 0.0078 15.7 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EEQ74348.1 - 0.029 13.5 15.9 0.25 10.4 1.0 4.5 2 2 1 4 4 4 0 Reovirus sigma C capsid protein AAA_25 PF13481.1 EEQ74348.1 - 0.034 13.5 0.8 0.098 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 EEQ74348.1 - 0.066 11.6 67.8 0.27 9.6 12.0 4.6 3 2 1 4 4 4 0 AAA domain ABC_tran PF00005.22 EEQ74348.1 - 0.077 13.2 0.0 0.077 13.2 0.0 4.5 5 1 0 5 5 5 0 ABC transporter AAA_22 PF13401.1 EEQ74348.1 - 0.67 10.1 8.7 1 9.5 0.0 3.8 3 2 0 3 3 3 0 AAA domain DASH_Dam1 PF08653.5 EEQ74348.1 - 2.1 8.1 5.6 2.7 7.8 0.1 4.0 4 1 1 5 5 5 0 DASH complex subunit Dam1 FAD_binding_4 PF01565.18 EEQ74349.1 - 4.6e-11 42.3 0.0 8.3e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain InaF-motif PF15018.1 EEQ74349.1 - 0.49 9.8 5.9 1.5 8.3 4.1 1.8 1 0 0 1 1 1 0 TRP-interacting helix RGS PF00615.14 EEQ74350.1 - 1.4e-09 38.1 0.5 2.3e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF368 PF04018.8 EEQ74350.1 - 0.017 14.2 0.4 0.027 13.6 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF368) Fibrillarin PF01269.12 EEQ74350.1 - 0.055 12.3 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin DUF4231 PF14015.1 EEQ74350.1 - 0.23 11.4 0.9 0.41 10.6 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF3649 PF12365.3 EEQ74350.1 - 0.26 10.8 1.6 0.74 9.3 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3649) DUF2655 PF10848.3 EEQ74351.1 - 0.11 12.4 0.0 1.4 8.8 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2655) Lipase_3 PF01764.20 EEQ74352.1 - 1e-15 57.5 0.0 5.2e-14 52.0 0.0 2.4 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EEQ74352.1 - 0.016 14.9 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF4267 PF14087.1 EEQ74353.1 - 2.3e-14 52.9 2.4 2.5e-14 52.8 1.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF2892 PF11127.3 EEQ74353.1 - 4.6 7.1 6.8 17 5.3 4.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2892) Ax_dynein_light PF10211.4 EEQ74354.1 - 0.0014 18.5 3.3 0.0018 18.1 2.3 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain BBS2_C PF14782.1 EEQ74354.1 - 0.0019 16.8 0.5 0.0022 16.6 0.4 1.0 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal IncA PF04156.9 EEQ74354.1 - 0.0025 17.4 0.3 0.0031 17.1 0.2 1.1 1 0 0 1 1 1 1 IncA protein FliT PF05400.8 EEQ74354.1 - 0.022 15.1 5.6 0.031 14.6 3.9 1.2 1 0 0 1 1 1 0 Flagellar protein FliT DUF1465 PF07323.7 EEQ74354.1 - 0.038 13.5 1.8 0.049 13.2 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) Fmp27_WPPW PF10359.4 EEQ74354.1 - 0.15 10.4 2.3 0.16 10.3 1.6 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4615 PF15393.1 EEQ74354.1 - 0.15 12.3 1.8 0.2 11.9 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) DivIC PF04977.10 EEQ74354.1 - 0.23 10.9 3.5 0.2 11.1 1.6 1.5 1 1 1 2 2 2 0 Septum formation initiator OmpH PF03938.9 EEQ74354.1 - 0.37 10.7 4.9 0.47 10.3 3.4 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MerR-DNA-bind PF09278.6 EEQ74354.1 - 1.9 8.9 7.4 3.1 8.2 3.3 2.1 1 1 1 2 2 2 0 MerR, DNA binding His_Phos_1 PF00300.17 EEQ74355.1 - 1.9e-31 109.2 0.1 2.3e-31 109.0 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DASH_Hsk3 PF08227.6 EEQ74356.1 - 2.5e-19 69.1 2.0 5.2e-19 68.1 1.4 1.6 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like FAD-SLDH PF12318.3 EEQ74356.1 - 0.066 12.9 2.3 0.09 12.4 1.6 1.2 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase AlaDh_PNT_N PF05222.10 EEQ74356.1 - 0.093 12.7 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain TMPIT PF07851.8 EEQ74356.1 - 0.11 11.5 0.5 0.13 11.3 0.3 1.0 1 0 0 1 1 1 0 TMPIT-like protein FAM196 PF15265.1 EEQ74356.1 - 0.13 11.4 5.6 0.17 11.1 3.9 1.0 1 0 0 1 1 1 0 FAM196 family Vac7 PF12751.2 EEQ74356.1 - 0.14 11.0 7.1 0.16 10.7 4.9 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Not3 PF04065.10 EEQ74356.1 - 0.25 10.5 1.7 0.32 10.2 1.1 1.2 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component UPF0449 PF15136.1 EEQ74356.1 - 0.29 11.3 1.1 0.41 10.8 0.8 1.4 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 RCR PF12273.3 EEQ74356.1 - 3.2 8.3 10.2 4.1 7.9 7.1 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Peptidase_S8 PF00082.17 EEQ74356.1 - 3.5 6.6 13.1 6.8 5.7 7.9 1.8 1 1 1 2 2 2 0 Subtilase family ApbA PF02558.11 EEQ74357.1 - 1.9e-24 85.8 0.0 3e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EEQ74357.1 - 8.6e-23 80.6 0.0 1.4e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DEAD PF00270.24 EEQ74359.1 - 9.7e-36 122.8 0.0 1.8e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ74359.1 - 4.1e-24 84.2 0.0 4.4e-23 80.9 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ74359.1 - 1.2e-05 25.2 0.0 3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EEQ74359.1 - 0.013 14.5 0.0 0.039 13.0 0.0 1.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Rpr2 PF04032.11 EEQ74360.1 - 1.9e-25 88.5 7.0 2.1e-24 85.2 4.9 2.1 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF2365 PF10157.4 EEQ74361.1 - 0.00053 19.9 1.6 0.0007 19.5 1.1 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) Perilipin PF03036.11 EEQ74361.1 - 0.022 13.6 0.1 0.026 13.3 0.1 1.2 1 0 0 1 1 1 0 Perilipin family DivIVA PF05103.8 EEQ74361.1 - 0.039 14.0 0.3 0.068 13.2 0.2 1.5 1 0 0 1 1 1 0 DivIVA protein ING PF12998.2 EEQ74361.1 - 0.073 13.3 3.0 0.16 12.2 0.5 2.1 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Syntaxin PF00804.20 EEQ74361.1 - 0.085 13.0 1.4 4.8 7.3 1.0 2.4 1 1 0 1 1 1 0 Syntaxin Snapin_Pallidin PF14712.1 EEQ74361.1 - 0.14 12.4 4.7 1.4 9.2 0.8 2.3 1 1 1 2 2 2 0 Snapin/Pallidin Tup_N PF08581.5 EEQ74361.1 - 0.22 11.7 4.9 0.56 10.4 3.4 1.7 1 1 0 1 1 1 0 Tup N-terminal BLOC1_2 PF10046.4 EEQ74361.1 - 0.22 11.6 1.6 0.69 10.0 0.7 1.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RasGAP_C PF03836.10 EEQ74361.1 - 0.24 11.0 4.9 0.34 10.5 3.4 1.2 1 0 0 1 1 1 0 RasGAP C-terminus DUF745 PF05335.8 EEQ74361.1 - 0.45 10.0 3.4 0.2 11.1 0.7 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF745) IncA PF04156.9 EEQ74361.1 - 0.74 9.3 6.0 2.3 7.7 4.0 1.6 1 1 1 2 2 2 0 IncA protein Wbp11 PF09429.5 EEQ74362.1 - 4e-23 81.1 14.1 4e-23 81.1 9.8 1.7 2 0 0 2 2 2 1 WW domain binding protein 11 DUF3450 PF11932.3 EEQ74362.1 - 0.22 10.7 2.8 0.34 10.1 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Pkinase PF00069.20 EEQ74363.1 - 9.3e-59 198.6 0.0 1.6e-58 197.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ74363.1 - 2.6e-35 121.7 0.0 5.6e-25 87.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEQ74363.1 - 0.0058 15.6 0.1 0.016 14.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like DUF4403 PF14356.1 EEQ74363.1 - 0.021 13.1 0.1 0.031 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4403) Stathmin PF00836.14 EEQ74363.1 - 0.62 9.6 11.5 1.5 8.4 8.0 1.6 1 0 0 1 1 1 0 Stathmin family BTB PF00651.26 EEQ74364.1 - 6.3e-22 77.6 0.0 1.9e-12 47.1 0.1 3.1 4 0 0 4 4 4 2 BTB/POZ domain Ank_2 PF12796.2 EEQ74364.1 - 9.8e-06 25.8 0.0 2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ74364.1 - 5.8e-05 22.6 0.3 0.026 14.3 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EEQ74364.1 - 6.7e-05 23.2 0.2 0.0045 17.4 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ74364.1 - 0.0041 17.3 0.3 3.8 7.8 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) zf-C2H2 PF00096.21 EEQ74365.1 - 6.6e-08 32.4 16.9 0.00087 19.4 3.2 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEQ74365.1 - 1.4e-06 28.2 2.1 1.4e-06 28.2 1.5 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEQ74365.1 - 0.0024 18.0 14.2 0.0089 16.2 2.0 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EEQ74365.1 - 0.089 13.0 5.3 0.4 10.9 1.4 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.10 EEQ74365.1 - 0.27 11.0 9.7 0.51 10.1 0.9 2.5 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.5 EEQ74365.1 - 0.37 10.7 2.1 4.7 7.2 0.2 2.3 2 0 0 2 2 2 0 Zinc ribbon domain TRP_N PF14558.1 EEQ74367.1 - 5.7e-08 32.8 0.0 9.9e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 ML-like domain TRP PF06011.7 EEQ74367.1 - 9.6e-08 31.0 14.3 5.7e-07 28.4 3.7 2.2 1 1 0 2 2 2 2 Transient receptor potential (TRP) ion channel Amidohydro_3 PF07969.6 EEQ74368.1 - 0.2 10.8 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase family Fungal_trans PF04082.13 EEQ74369.1 - 5.2e-14 51.7 0.7 1.1e-13 50.6 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EEQ74369.1 - 0.00042 20.4 0.9 0.0012 19.0 0.6 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ74369.1 - 0.00088 19.4 1.3 0.0023 18.1 0.9 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.2 EEQ74369.1 - 0.063 13.5 0.2 0.15 12.3 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type NAC PF01849.13 EEQ74370.1 - 3.5e-21 74.4 0.2 6.8e-21 73.5 0.1 1.5 1 0 0 1 1 1 1 NAC domain IFT57 PF10498.4 EEQ74370.1 - 0.37 9.4 3.9 0.39 9.4 0.5 1.9 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Sigma70_ner PF04546.8 EEQ74370.1 - 0.6 9.6 5.5 0.45 10.0 1.7 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF4604 PF15377.1 EEQ74370.1 - 2.9 8.0 8.8 0.35 11.0 1.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Nup35_RRM PF05172.8 EEQ74371.1 - 0.00078 19.1 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif adh_short PF00106.20 EEQ74373.1 - 9.7e-15 54.8 0.1 4.6e-12 46.1 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ74373.1 - 5.8e-05 22.8 0.0 0.00024 20.8 0.0 1.8 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EEQ74373.1 - 0.00045 20.0 0.0 0.037 13.7 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EEQ74373.1 - 0.0071 15.8 0.0 0.013 14.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_6 PF08030.7 EEQ74374.1 - 3.3e-20 72.5 0.0 2.1e-19 69.9 0.0 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EEQ74374.1 - 8.5e-16 57.7 0.0 1.7e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EEQ74374.1 - 1.9e-15 57.0 12.1 1.9e-15 57.0 8.4 1.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EEQ74374.1 - 0.049 13.7 0.0 0.17 12.0 0.0 1.9 1 1 0 1 1 1 0 Oxidoreductase FAD-binding domain Ctr PF04145.10 EEQ74375.1 - 1.6e-31 109.3 0.7 1.9e-31 109.0 0.5 1.0 1 0 0 1 1 1 1 Ctr copper transporter family DUF1049 PF06305.6 EEQ74375.1 - 6.7 6.2 7.0 15 5.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Abhydrolase_2 PF02230.11 EEQ74378.1 - 1.3e-53 181.6 0.0 1.6e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EEQ74378.1 - 2.7e-12 46.6 0.0 4.1e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEQ74378.1 - 1.7e-06 27.4 0.1 0.00074 18.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EEQ74378.1 - 1.9e-06 27.9 0.0 0.0076 16.1 0.0 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EEQ74378.1 - 5.1e-06 26.2 0.0 0.012 15.1 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.8 EEQ74378.1 - 0.011 15.1 0.0 0.049 13.0 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydro_lipase PF04083.11 EEQ74378.1 - 0.019 14.2 0.0 0.48 9.8 0.0 2.4 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region DLH PF01738.13 EEQ74378.1 - 0.021 14.1 0.0 0.053 12.8 0.0 1.6 1 1 0 1 1 1 0 Dienelactone hydrolase family LIP PF03583.9 EEQ74378.1 - 0.032 13.4 0.0 0.49 9.5 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase DUF1687 PF07955.6 EEQ74379.1 - 1.5e-13 50.8 0.0 1.1e-12 48.1 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) Pkinase PF00069.20 EEQ74380.1 - 1.3e-56 191.6 0.1 8.9e-56 188.9 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ74380.1 - 1.9e-28 99.2 0.2 7.5e-20 71.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EEQ74380.1 - 1.3e-05 25.6 0.1 2.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EEQ74380.1 - 0.00038 19.5 0.1 0.0036 16.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEQ74380.1 - 0.0011 18.7 3.5 0.25 11.0 0.0 3.7 2 1 2 4 4 4 2 Phosphotransferase enzyme family Fungal_trans_2 PF11951.3 EEQ74382.1 - 3.8e-57 193.6 0.6 5.1e-57 193.2 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ74382.1 - 3.3e-07 30.0 12.6 6.8e-07 29.0 8.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyridoxal_deC PF00282.14 EEQ74383.1 - 7.7e-63 212.1 0.0 1e-62 211.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EEQ74383.1 - 0.0022 16.7 0.0 0.004 15.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V LysM PF01476.15 EEQ74384.1 - 5e-15 55.1 1.6 0.00046 20.0 0.0 5.1 6 0 0 6 6 6 4 LysM domain Glyco_hydro_18 PF00704.23 EEQ74385.1 - 2.5e-71 240.9 0.8 3.3e-71 240.5 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Nitr_red_assoc PF09655.5 EEQ74386.1 - 0.011 16.0 0.6 0.11 12.8 0.1 2.3 1 1 0 2 2 2 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) zf-C2H2 PF00096.21 EEQ74387.1 - 1.1e-09 38.0 15.5 7.8e-05 22.7 0.8 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ74387.1 - 6.4e-09 35.5 8.7 4.5e-05 23.4 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EEQ74387.1 - 6.2e-08 32.5 9.4 9.3e-07 28.8 1.1 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.1 EEQ74387.1 - 0.0076 16.4 7.7 0.043 14.0 1.8 3.0 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 EEQ74387.1 - 0.016 15.3 3.5 0.019 15.0 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EEQ74387.1 - 0.21 11.5 5.9 7.7 6.5 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger DLH PF01738.13 EEQ74390.1 - 2.8e-12 46.3 0.0 3.3e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EEQ74390.1 - 0.00019 21.1 0.0 0.00025 20.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ74390.1 - 0.0023 17.5 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Zn_clus PF00172.13 EEQ74393.1 - 5e-07 29.5 7.3 7.3e-07 28.9 5.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GATA PF00320.22 EEQ74394.1 - 1.4e-16 59.5 1.9 3.3e-16 58.3 1.3 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EEQ74394.1 - 9.5e-14 50.6 5.3 2e-13 49.6 3.7 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) F-box PF00646.28 EEQ74395.1 - 0.00055 19.5 0.1 0.0018 17.8 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EEQ74395.1 - 0.0096 15.6 0.1 0.022 14.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like zf-CHY PF05495.7 EEQ74395.1 - 0.07 13.2 0.6 6.2 7.0 0.0 2.4 2 0 0 2 2 2 0 CHY zinc finger Stc1 PF12898.2 EEQ74395.1 - 0.077 13.0 2.7 0.49 10.4 0.2 2.3 1 1 1 2 2 2 0 Stc1 domain DZR PF12773.2 EEQ74395.1 - 0.097 12.5 3.0 0.55 10.1 0.4 2.8 1 1 1 2 2 2 0 Double zinc ribbon F-box-like PF12937.2 EEQ74396.1 - 0.0099 15.5 0.2 0.03 14.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.20 EEQ74398.1 - 3e-25 88.8 0.0 1.3e-24 86.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ74398.1 - 2.6e-08 33.2 0.9 6.4e-05 22.1 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EEQ74398.1 - 0.017 14.8 2.0 0.36 10.5 0.3 2.4 1 1 0 2 2 2 0 Phosphotransferase enzyme family Hexose_dehydrat PF03559.9 EEQ74398.1 - 0.045 12.7 0.4 0.1 11.6 0.3 1.5 1 0 0 1 1 1 0 NDP-hexose 2,3-dehydratase RE_ScaI PF09569.5 EEQ74399.1 - 0.12 11.8 0.2 5.6 6.4 0.0 2.0 1 1 1 2 2 2 0 ScaI restriction endonuclease zf-AN1 PF01428.11 EEQ74400.1 - 7.5e-12 44.9 11.7 1.1e-11 44.4 8.1 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger FeS PF04060.8 EEQ74400.1 - 0.57 9.8 0.0 0.57 9.8 0.0 2.6 2 1 1 3 3 3 0 Putative Fe-S cluster Transp_Tc5_C PF04236.10 EEQ74400.1 - 0.62 10.3 4.9 0.34 11.1 2.1 1.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain DUF1754 PF08555.5 EEQ74402.1 - 1.4e-13 51.2 3.5 1.4e-13 51.2 2.4 1.5 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Corona_nucleoca PF00937.13 EEQ74402.1 - 1.6 7.6 8.3 2 7.2 5.7 1.3 1 1 0 1 1 1 0 Coronavirus nucleocapsid protein SR-25 PF10500.4 EEQ74402.1 - 2.4 7.5 15.6 5.5 6.3 10.8 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein PTPA PF03095.10 EEQ74403.1 - 1.6e-110 369.0 0.0 1.9e-110 368.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF202 PF02656.10 EEQ74404.1 - 3e-23 81.8 0.7 3e-23 81.8 0.5 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF202) Phage_lysozyme PF00959.14 EEQ74407.1 - 2.2e-17 63.3 0.0 2.9e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Phage lysozyme NAD_synthase PF02540.12 EEQ74408.1 - 1.3e-24 86.4 0.0 8.4e-23 80.5 0.0 2.8 2 1 0 2 2 2 1 NAD synthase CN_hydrolase PF00795.17 EEQ74408.1 - 2.9e-24 85.4 0.0 5.9e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asn_synthase PF00733.16 EEQ74408.1 - 0.0085 15.6 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase DUF3115 PF11312.3 EEQ74409.1 - 2.5e-94 315.7 0.0 3.6e-94 315.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) GRAS PF03514.9 EEQ74409.1 - 0.064 11.9 0.0 0.096 11.3 0.0 1.2 1 0 0 1 1 1 0 GRAS domain family Cutinase PF01083.17 EEQ74411.1 - 5.5e-40 136.9 0.0 6.4e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EEQ74411.1 - 0.0088 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_5 PF12695.2 EEQ74411.1 - 0.055 13.2 0.0 0.086 12.5 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family HTH_38 PF13936.1 EEQ74413.1 - 4.8e-06 26.0 2.2 1.2e-05 24.7 0.6 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EEQ74413.1 - 6.3e-05 22.4 0.5 0.0002 20.8 0.2 1.9 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EEQ74413.1 - 0.00031 20.1 0.3 0.00092 18.6 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_28 PF13518.1 EEQ74413.1 - 0.043 13.8 0.4 0.19 11.7 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain PAT1 PF09770.4 EEQ74413.1 - 3.5 5.7 23.8 4.5 5.3 16.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AA_permease PF00324.16 EEQ74414.1 - 3.3e-130 434.6 49.9 3.7e-130 434.4 34.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ74414.1 - 3.1e-31 108.3 57.2 3.6e-31 108.1 39.6 1.0 1 0 0 1 1 1 1 Amino acid permease Band_7 PF01145.20 EEQ74415.1 - 8.2e-25 87.7 5.2 1.6e-24 86.8 3.6 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family UcrQ PF02939.11 EEQ74416.1 - 4.7e-27 93.6 0.3 6e-27 93.2 0.2 1.0 1 0 0 1 1 1 1 UcrQ family DUF3506 PF12014.3 EEQ74416.1 - 0.13 12.0 0.1 0.24 11.2 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3506) Copper-fist PF00649.13 EEQ74418.1 - 0.0017 17.4 0.6 0.0017 17.4 0.4 1.9 1 1 1 2 2 2 1 Copper fist DNA binding domain Zn_Tnp_IS91 PF14319.1 EEQ74418.1 - 0.026 14.0 4.8 0.029 13.8 3.3 1.1 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-CCHC PF00098.18 EEQ74418.1 - 0.13 12.2 0.9 0.13 12.2 0.6 2.1 3 0 0 3 3 3 0 Zinc knuckle DUF164 PF02591.10 EEQ74418.1 - 0.26 11.1 2.4 13 5.6 0.2 2.3 2 1 0 2 2 2 0 Putative zinc ribbon domain Thioredoxin_2 PF13098.1 EEQ74418.1 - 3.1 8.0 6.1 0.42 10.8 0.8 1.8 1 1 1 2 2 2 0 Thioredoxin-like domain eIF3g PF12353.3 EEQ74418.1 - 3.8 7.4 11.9 3.1 7.7 1.1 2.2 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Ribosomal_L7Ae PF01248.21 EEQ74419.1 - 5.7e-19 67.4 1.5 4.6e-18 64.5 1.0 2.2 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MMR_HSR1_C PF08438.5 EEQ74420.1 - 6.8e-32 109.9 0.0 1.3e-31 109.0 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EEQ74420.1 - 1.4e-18 66.9 0.0 3.4e-18 65.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEQ74420.1 - 5.8e-09 35.4 0.0 1.6e-07 30.7 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EEQ74420.1 - 0.0038 16.6 0.0 1.2 8.5 0.0 2.7 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EEQ74420.1 - 0.0059 16.8 0.1 0.63 10.3 0.0 2.3 2 0 0 2 2 2 1 ABC transporter Dynamin_N PF00350.18 EEQ74420.1 - 0.011 15.6 1.3 0.16 11.8 0.3 2.7 3 0 0 3 3 3 0 Dynamin family VirB8 PF04335.8 EEQ74420.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 VirB8 protein KTI12 PF08433.5 EEQ74420.1 - 0.13 11.4 0.0 0.31 10.2 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ATP_bind_1 PF03029.12 EEQ74420.1 - 0.14 11.6 0.1 16 4.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein rve PF00665.21 EEQ74423.1 - 0.00012 22.2 0.0 0.00023 21.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EEQ74423.1 - 0.0063 15.8 0.4 0.026 13.9 0.1 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Acetyltransf_4 PF13420.1 EEQ74423.1 - 0.012 15.6 0.6 0.034 14.0 0.4 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-CCHC PF00098.18 EEQ74426.1 - 0.13 12.2 0.9 0.13 12.2 0.6 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-C4pol PF14260.1 EEQ74426.1 - 1 9.4 8.8 0.86 9.6 3.6 2.0 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta NDUF_B4 PF07225.7 EEQ74428.1 - 7.7e-05 22.4 0.0 8.5e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) SAP18 PF06487.7 EEQ74429.1 - 6.5e-46 155.0 0.0 7.9e-46 154.7 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Prp18 PF02840.10 EEQ74430.1 - 1.1e-54 184.1 0.1 1.1e-54 184.1 0.1 2.0 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 EEQ74430.1 - 2.3e-11 42.7 0.2 2.3e-11 42.7 0.2 3.3 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like MAP7 PF05672.6 EEQ74430.1 - 0.0022 17.3 27.1 0.0022 17.3 18.8 1.7 2 0 0 2 2 2 1 MAP7 (E-MAP-115) family CAF-1_p150 PF11600.3 EEQ74430.1 - 0.052 12.9 31.6 0.11 11.9 21.9 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC27 PF09507.5 EEQ74430.1 - 1.5 7.9 19.9 2.2 7.3 13.8 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Pyr_redox_3 PF13738.1 EEQ74431.1 - 1.7e-05 25.0 0.0 0.00021 21.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase MAM PF00629.18 EEQ74433.1 - 0.026 14.3 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 MAM domain Pkinase PF00069.20 EEQ74434.1 - 6.8e-12 45.0 0.0 8.7e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ74434.1 - 3.6e-09 36.0 0.0 6.9e-09 35.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ74434.1 - 4.1e-06 26.7 0.7 0.0011 18.7 0.7 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EEQ74434.1 - 0.00018 20.5 0.0 0.00027 19.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EEQ74434.1 - 0.17 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4344 PF14247.1 EEQ74436.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4344) DUF3451 PF11933.3 EEQ74438.1 - 0.01 15.6 0.1 0.011 15.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3451) DUF1777 PF08648.7 EEQ74438.1 - 0.2 11.3 3.9 0.3 10.7 2.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) Fmp27_SW PF10305.4 EEQ74439.1 - 1.4 9.3 4.9 0.37 11.2 0.8 1.8 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain zf-tcix PF14952.1 EEQ74441.1 - 0.0097 15.2 0.2 0.018 14.3 0.2 1.4 1 0 0 1 1 1 1 Putative treble-clef, zinc-finger, Zn-binding Amidase PF01425.16 EEQ74443.1 - 1.6e-105 353.4 0.0 3.9e-102 342.3 0.0 2.2 1 1 0 1 1 1 1 Amidase DUF605 PF04652.11 EEQ74444.1 - 8.7 5.6 12.5 13 5.0 8.7 1.3 1 0 0 1 1 1 0 Vta1 like Bystin PF05291.6 EEQ74445.1 - 1.5e-127 424.6 0.0 2.1e-127 424.2 0.0 1.1 1 0 0 1 1 1 1 Bystin ASD2 PF08687.6 EEQ74445.1 - 0.047 13.0 0.1 0.097 11.9 0.0 1.4 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 bZIP_2 PF07716.10 EEQ74447.1 - 2e-09 37.0 20.3 3.1e-09 36.5 9.2 2.5 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 EEQ74447.1 - 5.5e-05 23.0 15.5 0.00025 20.9 10.7 2.1 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EEQ74447.1 - 0.0023 18.1 11.8 0.0048 17.1 8.1 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor APG6 PF04111.7 EEQ74447.1 - 0.45 9.5 4.8 0.69 8.8 3.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 EEQ74447.1 - 8.2 5.9 6.6 0.68 9.4 0.5 2.0 1 1 1 2 2 2 0 Septum formation initiator CTF_NFI PF00859.13 EEQ74448.1 - 0.093 12.4 1.2 0.18 11.5 0.1 1.8 2 0 0 2 2 2 0 CTF/NF-I family transcription modulation region Caps_synth PF05704.7 EEQ74450.1 - 1.6e-09 37.3 0.0 2.9e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 EEQ74450.1 - 0.0065 16.8 0.1 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif AMP-binding PF00501.23 EEQ74451.1 - 1.5e-78 264.0 0.0 2.1e-78 263.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EEQ74451.1 - 2.8e-54 183.6 0.0 8.1e-54 182.1 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.20 EEQ74451.1 - 1.5e-13 50.7 0.2 3e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EEQ74451.1 - 4.6e-10 39.3 0.0 1.5e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEQ74451.1 - 0.012 14.3 0.0 0.11 11.2 0.0 2.4 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EEQ74452.1 - 7.4e-42 143.1 0.0 1.1e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEQ74452.1 - 9.1e-14 51.8 0.0 1.4e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 EEQ74452.1 - 0.011 16.1 0.3 0.68 10.4 0.1 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 EEQ74452.1 - 0.018 13.7 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EEQ74452.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Glyphos_transf PF04464.9 EEQ74453.1 - 0.02 13.6 0.0 0.028 13.1 0.0 1.1 1 0 0 1 1 1 0 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase PGM_PMM_II PF02879.11 EEQ74453.1 - 0.085 13.1 0.0 0.33 11.3 0.0 2.0 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II FAD_binding_3 PF01494.14 EEQ74454.1 - 3.6e-61 207.1 0.0 3.9e-60 203.8 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EEQ74454.1 - 1.7e-14 53.7 0.0 3.3e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.5 EEQ74454.1 - 0.0031 16.3 0.0 0.0058 15.5 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.9 EEQ74454.1 - 0.0089 14.7 0.0 0.016 13.8 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase MFS_1 PF07690.11 EEQ74455.1 - 4.9e-39 134.0 73.8 1.4e-35 122.6 32.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ74455.1 - 5.5e-09 35.1 15.6 5.5e-09 35.1 10.8 3.1 3 1 0 3 3 3 1 Sugar (and other) transporter Ycf66_N PF07444.6 EEQ74455.1 - 0.025 14.3 1.0 0.025 14.3 0.7 3.3 3 0 0 3 3 3 0 Ycf66 protein N-terminus MFS_1_like PF12832.2 EEQ74455.1 - 0.2 11.4 9.1 4.4 7.1 0.0 3.4 3 0 0 3 3 3 0 MFS_1 like family Methyltransf_25 PF13649.1 EEQ74456.1 - 9.4e-11 41.9 0.0 1.5e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ74456.1 - 4.8e-10 40.0 0.0 8.6e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ74456.1 - 3e-07 30.8 0.0 6.6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ74456.1 - 3.1e-07 30.1 0.0 4.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ74456.1 - 1.5e-06 28.5 0.0 3e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ74456.1 - 1.9e-06 27.7 0.0 9.8e-06 25.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ74456.1 - 1.5e-05 25.0 0.2 3e-05 24.0 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEQ74456.1 - 0.015 14.3 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 EEQ74456.1 - 0.034 13.2 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Pkinase PF00069.20 EEQ74457.1 - 5.8e-18 64.9 0.7 2.4e-16 59.6 0.5 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ74457.1 - 1.7e-09 37.1 0.0 2.8e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EEQ74457.1 - 0.014 14.2 0.1 0.019 13.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EEQ74457.1 - 0.016 14.2 0.1 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ74457.1 - 0.049 13.3 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EEQ74457.1 - 0.087 12.1 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Actin PF00022.14 EEQ74461.1 - 2.3e-20 72.3 0.0 3.9e-19 68.3 0.0 2.6 2 1 0 2 2 2 1 Actin Med12-LCEWAV PF12145.3 EEQ74461.1 - 5.4 5.3 8.6 9 4.6 6.0 1.2 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain CBFD_NFYB_HMF PF00808.18 EEQ74462.1 - 2.9e-18 65.6 0.6 5.3e-18 64.8 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEQ74462.1 - 0.00041 20.4 0.0 0.00064 19.7 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EEQ74462.1 - 0.034 13.8 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated DAO PF01266.19 EEQ74463.1 - 4.9e-35 121.0 2.0 6.6e-35 120.6 1.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEQ74463.1 - 2.9e-05 24.0 0.1 6.6e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEQ74463.1 - 4.3e-05 23.4 0.0 0.042 13.7 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEQ74463.1 - 0.00096 19.5 0.0 0.0044 17.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEQ74463.1 - 0.0053 16.5 0.1 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding SMC_Nse1 PF07574.8 EEQ74464.1 - 1.5e-37 129.1 0.0 1.9e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EEQ74464.1 - 4.6e-10 39.3 9.5 7e-10 38.7 6.6 1.3 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.1 EEQ74464.1 - 0.071 12.9 8.1 0.11 12.3 5.6 1.3 1 0 0 1 1 1 0 Ring finger domain zf-HC5HC2H_2 PF13832.1 EEQ74464.1 - 0.37 10.8 5.9 1.3 9.0 4.2 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain IBR PF01485.16 EEQ74464.1 - 2.2 8.2 8.8 28 4.6 6.1 2.1 1 1 0 1 1 1 0 IBR domain zf-HC5HC2H PF13771.1 EEQ74464.1 - 3 8.0 7.9 23 5.2 5.5 2.1 1 1 1 2 2 2 0 PHD-like zinc-binding domain Glyco_hydro_65m PF03632.10 EEQ74465.1 - 3.1e-82 276.2 0.0 1.6e-81 273.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 EEQ74465.1 - 5.6e-51 173.2 0.0 9e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 EEQ74465.1 - 1.1e-06 28.6 0.1 6.1e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, C-terminal domain Catalase PF00199.14 EEQ74466.1 - 9.4e-158 524.8 0.8 1.2e-157 524.5 0.6 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EEQ74466.1 - 7e-21 73.8 0.0 1.4e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive MBOAT_2 PF13813.1 EEQ74467.1 - 5.1e-16 58.5 5.6 6.4e-15 55.0 0.3 3.6 1 1 1 2 2 2 1 Membrane bound O-acyl transferase family Pyridoxal_deC PF00282.14 EEQ74468.1 - 1.1e-82 277.4 0.0 1.7e-82 276.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EEQ74468.1 - 1.8e-06 27.2 0.0 7.5e-06 25.2 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase BTB PF00651.26 EEQ74471.1 - 0.00082 19.3 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Pyridox_ox_2 PF12900.2 EEQ74472.1 - 1.1e-21 77.1 0.0 1.2e-19 70.5 0.0 2.2 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pkinase PF00069.20 EEQ74474.1 - 2e-29 102.5 0.0 3.6e-29 101.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ74474.1 - 4.6e-06 25.9 0.6 0.0058 15.7 0.0 3.1 3 1 0 3 3 3 2 Protein tyrosine kinase DUF917 PF06032.7 EEQ74475.1 - 5.4e-97 324.4 0.9 2.3e-95 319.1 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EEQ74475.1 - 4.7e-50 170.3 10.6 1e-47 162.6 4.6 3.0 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EEQ74475.1 - 2.8e-26 92.1 5.6 6.2e-24 84.4 0.2 3.1 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EEQ74475.1 - 4.7e-06 25.1 1.7 0.0071 14.7 0.2 2.4 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.15 EEQ74475.1 - 0.00053 19.3 1.1 0.016 14.5 0.0 3.2 4 1 0 4 4 4 1 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.1 EEQ74475.1 - 0.01 15.6 6.0 2.8 7.7 0.0 4.5 4 0 0 4 4 4 0 Cell division protein FtsA StbA PF06406.6 EEQ74475.1 - 0.032 13.1 0.5 1.5 7.6 0.0 2.6 3 0 0 3 3 3 0 StbA protein DUF427 PF04248.7 EEQ74476.1 - 8.7e-27 92.6 0.2 9.9e-27 92.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) GDC-P PF02347.11 EEQ74477.1 - 1.9e-174 580.4 0.0 3.5e-160 533.3 0.0 2.7 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EEQ74477.1 - 8.7e-07 28.3 0.4 1.7e-06 27.4 0.0 1.5 2 0 0 2 2 2 1 Beta-eliminating lyase Amidohydro_1 PF01979.15 EEQ74478.1 - 2.7e-37 129.1 0.0 3.8e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EEQ74478.1 - 2.1e-07 30.5 1.9 3.7e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EEQ74478.1 - 2.2e-05 24.6 3.1 0.015 15.3 0.8 2.4 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EEQ74478.1 - 0.012 15.4 0.0 0.035 13.9 0.0 1.8 1 0 0 1 1 1 0 Amidohydrolase A_deaminase PF00962.17 EEQ74478.1 - 0.069 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Adenosine/AMP deaminase FAD_binding_3 PF01494.14 EEQ74479.1 - 2.2e-22 79.6 0.0 1.5e-11 43.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EEQ74479.1 - 4.5e-06 25.8 0.0 0.0028 16.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EEQ74479.1 - 6.6e-06 25.4 0.0 0.0013 17.8 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EEQ74479.1 - 3.3e-05 23.8 0.0 0.00033 20.6 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EEQ74479.1 - 0.0099 14.8 0.5 0.16 10.8 0.1 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.22 EEQ74479.1 - 0.025 14.9 0.9 0.06 13.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EEQ74479.1 - 0.041 12.6 0.0 5.7 5.6 0.0 2.3 2 0 0 2 2 2 0 Squalene epoxidase Sulfatase PF00884.18 EEQ74480.1 - 3e-60 204.0 0.1 3.8e-60 203.6 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 EEQ74480.1 - 6.3e-22 77.1 0.1 6.9e-21 73.8 0.0 2.3 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 EEQ74480.1 - 2.6e-10 40.1 1.0 2e-08 33.9 0.7 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 EEQ74480.1 - 0.003 17.8 0.5 0.0073 16.5 0.2 1.7 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase Metalloenzyme PF01676.13 EEQ74480.1 - 0.052 12.9 0.0 0.11 11.8 0.0 1.5 2 0 0 2 2 2 0 Metalloenzyme superfamily DUF229 PF02995.12 EEQ74480.1 - 0.065 11.6 0.0 0.08 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Peptidase_C16 PF01831.12 EEQ74480.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase C16 family Tox-HDC PF15656.1 EEQ74480.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature DnaJ PF00226.26 EEQ74483.1 - 1.4e-19 69.5 1.0 1.4e-19 69.5 0.7 2.7 3 1 0 3 3 3 1 DnaJ domain Complex1_LYR PF05347.10 EEQ74484.1 - 4e-05 23.3 0.1 6.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EEQ74484.1 - 0.00072 19.7 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like RRM_5 PF13893.1 EEQ74485.1 - 2.2e-11 43.4 0.0 4.4e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEQ74485.1 - 4e-09 35.9 0.0 7.3e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ74485.1 - 2e-05 24.4 0.0 3.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEQ74485.1 - 0.00089 18.9 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Sterol_MT_C PF08498.5 EEQ74486.1 - 1.4e-28 98.6 0.0 2.1e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EEQ74486.1 - 5.9e-18 65.1 0.0 1.1e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ74486.1 - 5.8e-14 51.9 0.0 8.8e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ74486.1 - 1.6e-12 47.6 0.0 2.9e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ74486.1 - 2e-12 47.1 0.0 3.2e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EEQ74486.1 - 1.1e-11 44.3 0.0 1.6e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EEQ74486.1 - 9.6e-11 42.0 0.0 2.2e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ74486.1 - 9.7e-10 39.0 0.0 2.1e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ74486.1 - 3.6e-08 32.8 0.0 6.1e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EEQ74486.1 - 4.7e-08 33.0 0.0 1.4e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EEQ74486.1 - 0.00028 20.4 0.0 0.00042 19.8 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 EEQ74486.1 - 0.002 17.3 0.0 0.0037 16.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EEQ74486.1 - 0.028 13.7 0.0 0.06 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_24 PF13578.1 EEQ74486.1 - 0.12 13.2 0.1 0.54 11.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.15 EEQ74486.1 - 0.15 11.0 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase HET PF06985.6 EEQ74487.1 - 1.4e-26 93.3 0.1 3.5e-26 92.0 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.14 EEQ74489.1 - 1.4e-19 70.4 0.2 2e-08 33.6 0.0 3.1 2 1 1 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 EEQ74489.1 - 0.00073 19.5 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEQ74489.1 - 0.0042 16.0 0.2 0.062 12.2 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EEQ74489.1 - 0.0099 16.2 0.0 0.071 13.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEQ74489.1 - 0.067 12.0 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EEQ74489.1 - 0.086 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 EEQ74489.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EEQ74489.1 - 0.16 10.7 0.0 3.5 6.3 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase FAD_binding_4 PF01565.18 EEQ74491.1 - 1.5e-14 53.6 0.0 1.9e-12 46.8 0.0 2.8 2 1 1 3 3 3 2 FAD binding domain DIOX_N PF14226.1 EEQ74492.1 - 1e-30 106.6 0.0 1.8e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EEQ74492.1 - 1.2e-15 57.6 0.0 2.6e-15 56.4 0.0 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily NmrA PF05368.8 EEQ74493.1 - 4.7e-60 202.7 0.1 6e-60 202.3 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEQ74493.1 - 1.3e-15 57.8 0.0 1.9e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EEQ74493.1 - 3.3e-06 26.0 0.0 4.7e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EEQ74493.1 - 0.012 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain RHINO PF15319.1 EEQ74494.1 - 0.00035 20.4 1.3 0.00045 20.1 0.9 1.1 1 0 0 1 1 1 1 RAD9, RAD1, HUS1-interacting nuclear orphan protein MARVEL PF01284.18 EEQ74495.1 - 1.2e-14 54.3 9.7 1.4e-14 54.1 6.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2644 PF10841.3 EEQ74495.1 - 0.052 13.5 0.6 4.9 7.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2644) DUF1056 PF06341.6 EEQ74495.1 - 8.1 6.5 6.7 4.7 7.3 0.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1056) Glyco_hydro_76 PF03663.9 EEQ74496.1 - 3.3e-146 487.4 1.9 4e-146 487.1 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EEQ74496.1 - 0.018 14.0 2.9 0.16 10.9 0.0 3.0 1 1 3 4 4 4 0 Glycosyl Hydrolase Family 88 PFK PF00365.15 EEQ74497.1 - 4.6e-165 547.4 0.4 2.5e-119 397.4 0.3 2.1 2 0 0 2 2 2 2 Phosphofructokinase Med17 PF10156.4 EEQ74498.1 - 1.3e-121 406.1 2.9 1.7e-121 405.7 2.0 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex ISN1 PF06437.6 EEQ74499.1 - 1.4e-192 639.9 0.0 1.6e-192 639.7 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Ank_2 PF12796.2 EEQ74500.1 - 5.3e-16 58.7 0.0 1.8e-11 44.2 0.0 3.7 2 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEQ74500.1 - 1.7e-14 53.4 0.0 9.3e-07 28.9 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEQ74500.1 - 2e-13 50.4 0.1 1.1e-05 25.8 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EEQ74500.1 - 5e-10 38.6 0.1 0.00066 19.3 0.0 4.7 6 0 0 6 6 6 2 Ankyrin repeat Ank_3 PF13606.1 EEQ74500.1 - 3.2e-06 26.8 0.0 0.018 15.2 0.0 4.4 5 0 0 5 5 3 1 Ankyrin repeat NACHT PF05729.7 EEQ74500.1 - 5.7e-05 22.8 0.3 0.00016 21.3 0.2 1.9 1 1 0 1 1 1 1 NACHT domain AAA PF00004.24 EEQ74500.1 - 0.0028 17.8 0.0 0.0081 16.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EEQ74500.1 - 0.003 17.0 0.1 0.005 16.3 0.1 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 EEQ74500.1 - 0.0036 17.4 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEQ74500.1 - 0.0063 17.3 0.0 0.025 15.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EEQ74500.1 - 0.011 14.6 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 EEQ74500.1 - 0.013 15.7 0.0 0.048 13.9 0.0 1.9 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.17 EEQ74500.1 - 0.024 14.8 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase MNHE PF01899.11 EEQ74500.1 - 0.04 13.5 0.0 0.097 12.2 0.0 1.6 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit KAP_NTPase PF07693.9 EEQ74500.1 - 0.058 12.3 0.7 6 5.7 0.1 2.2 2 0 0 2 2 2 0 KAP family P-loop domain AAA_30 PF13604.1 EEQ74500.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EEQ74500.1 - 0.098 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 EEQ74500.1 - 0.16 11.8 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEQ74500.1 - 0.16 11.8 0.4 22 4.9 0.0 2.9 1 1 2 3 3 3 0 AAA ATPase domain DUF87 PF01935.12 EEQ74500.1 - 0.2 11.4 0.2 0.64 9.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 cNMP_binding PF00027.24 EEQ74501.1 - 1.1e-37 127.7 0.0 7.5e-21 73.7 0.0 4.5 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 EEQ74501.1 - 1.5e-19 70.7 6.6 1.9e-18 67.1 4.6 2.6 1 1 0 1 1 1 1 Patatin-like phospholipase DUF2296 PF10058.4 EEQ74502.1 - 1.1e-19 69.8 0.1 2.1e-19 69.0 0.1 1.5 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) YL1 PF05764.8 EEQ74502.1 - 4.9 6.7 9.3 0.12 11.9 1.6 1.9 2 0 0 2 2 2 0 YL1 nuclear protein PGAP1 PF07819.8 EEQ74503.1 - 5.5e-06 26.1 0.0 1.5e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EEQ74503.1 - 3e-05 23.4 0.0 6.7e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EEQ74503.1 - 0.00042 20.2 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 EEQ74503.1 - 0.00064 18.7 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase NACHT PF05729.7 EEQ74503.1 - 0.00083 19.0 0.0 0.0019 17.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Abhydrolase_5 PF12695.2 EEQ74503.1 - 0.002 17.9 0.0 0.0047 16.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family APS_kinase PF01583.15 EEQ74503.1 - 0.0021 17.7 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.1 EEQ74503.1 - 0.055 13.4 0.0 0.18 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EEQ74503.1 - 0.11 12.6 0.0 0.43 10.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EEQ74503.1 - 0.15 11.7 0.0 0.75 9.4 0.0 2.1 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.17 EEQ74503.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF694 PF05107.7 EEQ74503.1 - 0.23 10.6 0.0 0.38 9.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF694) DUF3089 PF11288.3 EEQ74503.1 - 0.24 10.5 0.0 0.43 9.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Synaptobrevin PF00957.16 EEQ74504.1 - 2.1e-10 40.0 0.7 4.6e-10 38.9 0.5 1.5 1 0 0 1 1 1 1 Synaptobrevin Auxin_resp PF06507.8 EEQ74504.1 - 0.044 13.6 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Auxin response factor NusB PF01029.13 EEQ74504.1 - 0.12 12.3 0.5 0.23 11.4 0.4 1.5 1 0 0 1 1 1 0 NusB family TBCA PF02970.11 EEQ74504.1 - 0.14 12.2 1.8 0.28 11.2 1.2 1.4 1 0 0 1 1 1 0 Tubulin binding cofactor A Sec63 PF02889.11 EEQ74505.1 - 3.5e-145 483.0 0.0 2e-94 316.3 0.1 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EEQ74505.1 - 1.1e-54 184.4 2.1 1.8e-28 99.1 1.0 4.5 5 0 0 5 5 5 2 DEAD/DEAH box helicase ResIII PF04851.10 EEQ74505.1 - 9.8e-17 61.3 0.0 7.8e-08 32.3 0.1 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EEQ74505.1 - 3.9e-15 55.4 0.0 3e-07 30.1 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 EEQ74505.1 - 4.2e-07 30.1 0.1 0.056 13.5 0.0 3.3 2 2 0 2 2 2 2 AAA domain SNF2_N PF00176.18 EEQ74505.1 - 1.2e-05 24.2 0.2 0.11 11.2 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA_19 PF13245.1 EEQ74505.1 - 1.3e-05 24.8 0.4 0.018 14.7 0.0 3.1 3 0 0 3 3 3 2 Part of AAA domain AAA_25 PF13481.1 EEQ74505.1 - 0.0054 16.1 0.2 2.3 7.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EEQ74505.1 - 0.0064 15.9 0.0 1.1 8.6 0.0 3.0 3 0 0 3 3 3 1 FtsK/SpoIIIE family PhoH PF02562.11 EEQ74505.1 - 0.018 14.2 0.0 4.6 6.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.12 EEQ74505.1 - 0.025 14.0 0.3 7.7 5.8 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_10 PF12846.2 EEQ74505.1 - 0.032 13.6 0.0 4.2 6.7 0.0 3.6 3 1 0 3 3 3 0 AAA-like domain Zeta_toxin PF06414.7 EEQ74505.1 - 0.07 12.2 0.3 6 5.8 0.0 3.4 4 0 0 4 4 4 0 Zeta toxin Profilin PF00235.14 EEQ74508.1 - 7e-22 77.7 0.0 7.9e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Profilin Got1 PF04178.7 EEQ74510.1 - 7.9e-12 45.3 12.1 1e-11 44.9 8.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family ATP1G1_PLM_MAT8 PF02038.11 EEQ74510.1 - 0.79 8.7 7.1 0.93 8.5 0.4 2.3 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family YL1_C PF08265.6 EEQ74511.1 - 1.7e-16 59.4 0.2 2.9e-16 58.7 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Pol_alpha_B_N PF08418.5 EEQ74511.1 - 0.11 12.0 1.7 0.13 11.8 1.2 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Herpes_capsid PF06112.6 EEQ74511.1 - 0.7 9.9 6.2 1.3 9.0 4.3 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Actin PF00022.14 EEQ74512.1 - 6.7e-53 179.5 0.0 3.7e-30 104.6 0.0 2.2 2 0 0 2 2 2 2 Actin bZIP_1 PF00170.16 EEQ74513.1 - 5.6e-07 29.4 7.2 5.6e-07 29.4 5.0 2.3 2 1 0 2 2 2 1 bZIP transcription factor HALZ PF02183.13 EEQ74513.1 - 0.016 14.9 0.2 0.016 14.9 0.1 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF501 PF04417.7 EEQ74513.1 - 0.063 13.1 0.3 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF501) bZIP_2 PF07716.10 EEQ74513.1 - 6.7 6.6 17.1 9.4 6.1 6.3 3.6 3 1 0 3 3 3 0 Basic region leucine zipper Brr6_like_C_C PF10104.4 EEQ74514.1 - 2.4e-44 150.1 0.7 3.2e-44 149.7 0.5 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Ctr PF04145.10 EEQ74514.1 - 0.059 13.4 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 Ctr copper transporter family AA_permease_2 PF13520.1 EEQ74515.1 - 2.7e-06 26.2 8.8 0.012 14.1 0.0 2.9 2 1 1 3 3 3 3 Amino acid permease DUF3521 PF12035.3 EEQ74515.1 - 0.098 12.5 0.1 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3521) Anoctamin PF04547.7 EEQ74516.1 - 4e-125 418.0 7.6 5.2e-125 417.6 5.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Alpha-2-MRAP_C PF06401.6 EEQ74516.1 - 0.005 16.7 0.2 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 Alpha-2-macroglobulin RAP, C-terminal domain Fungal_trans_2 PF11951.3 EEQ74517.1 - 2.6e-06 26.3 0.6 5.5e-06 25.2 0.4 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ74517.1 - 1.5e-05 24.7 11.9 1.5e-05 24.7 8.2 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.1 EEQ74518.1 - 6.2e-70 235.8 25.6 7.8e-70 235.5 17.7 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0182 PF03699.8 EEQ74518.1 - 0.88 7.4 4.2 1.3 6.8 2.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Fungal_trans_2 PF11951.3 EEQ74519.1 - 2.8e-67 226.9 4.0 3.7e-67 226.5 2.8 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ74519.1 - 2.5e-09 36.9 8.7 4.7e-09 36.0 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 EEQ74520.1 - 0.11 12.1 0.0 5.6 6.7 0.0 2.4 2 0 0 2 2 2 0 F-box-like DNA_binding_1 PF01035.15 EEQ74521.1 - 3e-20 71.7 0.0 4.6e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Bud13 PF09736.4 EEQ74522.1 - 2.7e-44 150.9 1.2 2.7e-44 150.9 0.8 2.6 3 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex Pkinase PF00069.20 EEQ74523.1 - 1.5e-40 139.0 0.3 1.2e-23 83.6 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ74523.1 - 1.7e-14 53.5 0.2 2.1e-10 40.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase DUF2789 PF10982.3 EEQ74524.1 - 0.089 12.8 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2789) Metallophos PF00149.23 EEQ74526.1 - 1.4e-08 34.3 9.6 7.9e-07 28.6 6.6 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEQ74526.1 - 7.4e-05 22.6 0.5 0.00026 20.8 0.3 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Lactamase_B_2 PF12706.2 EEQ74526.1 - 0.0013 18.3 0.4 0.85 9.1 0.1 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain FMN_dh PF01070.13 EEQ74527.1 - 2.2e-122 408.3 0.0 2.7e-122 408.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EEQ74527.1 - 4.1e-23 80.9 0.0 7.8e-23 80.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EEQ74527.1 - 1.1e-07 31.0 0.0 1.8e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EEQ74527.1 - 0.0012 17.8 0.1 0.0027 16.6 0.0 1.6 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EEQ74527.1 - 0.0021 17.2 0.0 0.0033 16.6 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 EEQ74527.1 - 0.1 11.8 0.2 1.2 8.4 0.0 2.2 1 1 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.9 EEQ74527.1 - 0.18 10.8 0.0 17 4.3 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Ras PF00071.17 EEQ74528.1 - 1.7e-39 134.8 0.0 8.7e-37 125.9 0.0 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EEQ74528.1 - 2.2e-19 70.0 0.0 3.1e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ74528.1 - 2.6e-11 43.0 0.0 4.3e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEQ74528.1 - 0.00017 20.8 0.0 0.00021 20.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEQ74528.1 - 0.0004 20.3 0.0 0.00064 19.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EEQ74528.1 - 0.00089 18.5 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EEQ74528.1 - 0.0018 18.4 0.0 0.0051 16.9 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEQ74528.1 - 0.007 16.3 0.1 0.024 14.6 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain PduV-EutP PF10662.4 EEQ74528.1 - 0.0079 15.6 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EEQ74528.1 - 0.053 13.4 0.4 0.098 12.6 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EEQ74528.1 - 0.055 13.3 0.0 0.086 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EEQ74528.1 - 0.056 12.6 0.2 0.085 12.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 EEQ74528.1 - 0.078 12.8 0.2 0.16 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EEQ74528.1 - 0.085 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_24 PF13479.1 EEQ74528.1 - 0.097 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EEQ74528.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain GRIP PF01465.15 EEQ74530.1 - 3.1e-18 65.0 0.1 6.5e-18 63.9 0.1 1.6 1 0 0 1 1 1 1 GRIP domain Reo_sigmaC PF04582.7 EEQ74530.1 - 3.9e-08 32.8 59.5 0.0011 18.1 8.7 6.6 4 2 3 7 7 7 4 Reovirus sigma C capsid protein IncA PF04156.9 EEQ74530.1 - 4.1e-07 29.8 150.7 0.00043 19.9 0.5 9.0 4 2 5 9 9 9 3 IncA protein CENP-F_leu_zip PF10473.4 EEQ74530.1 - 1.1e-05 25.2 152.9 0.0026 17.6 14.9 8.9 3 2 6 9 9 9 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 EEQ74530.1 - 2e-05 23.3 101.7 0.033 12.6 3.3 5.9 3 1 4 7 7 7 6 AAA domain GAS PF13851.1 EEQ74530.1 - 0.001 18.3 132.6 0.58 9.3 10.3 8.3 3 2 4 7 7 7 7 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 EEQ74530.1 - 0.0035 17.1 6.9 0.0035 17.1 4.8 14.4 7 2 8 16 16 15 5 TATA element modulatory factor 1 DNA binding CASP_C PF08172.7 EEQ74530.1 - 0.004 16.2 0.3 0.004 16.2 0.2 10.4 6 2 3 10 10 6 2 CASP C terminal Spc7 PF08317.6 EEQ74530.1 - 0.0065 15.1 125.5 0.0041 15.8 12.3 7.5 5 2 3 8 8 8 3 Spc7 kinetochore protein DivIC PF04977.10 EEQ74530.1 - 0.052 13.0 0.3 0.052 13.0 0.2 15.0 6 3 10 16 16 15 0 Septum formation initiator Filament PF00038.16 EEQ74530.1 - 0.11 12.0 139.9 0.063 12.7 12.6 7.5 4 1 5 9 9 7 0 Intermediate filament protein Myosin_tail_1 PF01576.14 EEQ74530.1 - 0.81 7.3 156.3 0.16 9.6 14.9 5.3 4 1 1 5 5 5 0 Myosin tail GldM_C PF12080.3 EEQ74530.1 - 1.2 9.0 6.6 4.4 7.2 0.3 3.1 2 0 0 2 2 2 0 GldM C-terminal domain WEMBL PF05701.6 EEQ74530.1 - 2.1 6.7 151.3 0.72 8.2 9.7 6.3 3 2 3 6 6 6 0 Weak chloroplast movement under blue light DUF869 PF05911.6 EEQ74530.1 - 6.3 4.8 130.3 1.2 7.2 19.9 6.1 2 1 3 6 6 6 0 Plant protein of unknown function (DUF869) DUF3638 PF12340.3 EEQ74532.1 - 1.4e-103 344.8 0.1 2.7e-103 343.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EEQ74532.1 - 8.4e-19 66.4 0.5 1.7e-18 65.4 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Amidase PF01425.16 EEQ74535.1 - 5.8e-33 114.4 0.0 2.5e-32 112.2 0.0 1.8 1 1 0 1 1 1 1 Amidase TPR_12 PF13424.1 EEQ74537.1 - 2.7e-13 49.6 8.5 0.0001 22.1 0.9 5.0 3 1 0 4 4 4 3 Tetratricopeptide repeat NB-ARC PF00931.17 EEQ74537.1 - 7.5e-11 41.4 0.0 1.9e-10 40.0 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain TPR_11 PF13414.1 EEQ74537.1 - 6.6e-08 32.0 2.8 0.0048 16.5 0.0 4.6 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 EEQ74537.1 - 1.3e-07 31.0 6.6 0.0052 16.5 0.0 5.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ74537.1 - 1.7e-06 27.3 8.7 0.00047 19.6 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ74537.1 - 0.00058 20.2 3.1 2.6 8.9 0.1 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_22 PF13401.1 EEQ74537.1 - 0.00058 19.9 0.0 0.0018 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Abhydrolase_6 PF12697.2 EEQ74537.1 - 0.001 18.9 0.0 0.004 17.0 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family RPN7 PF10602.4 EEQ74537.1 - 0.0018 17.6 1.7 0.15 11.4 0.0 2.6 1 1 1 2 2 2 1 26S proteasome subunit RPN7 DUF676 PF05057.9 EEQ74537.1 - 0.0032 16.7 0.0 0.0067 15.7 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_10 PF13374.1 EEQ74537.1 - 0.0068 16.3 0.1 21 5.2 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ74537.1 - 0.0068 16.1 5.3 0.11 12.2 0.1 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat PGAP1 PF07819.8 EEQ74537.1 - 0.014 14.9 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Foie-gras_1 PF11817.3 EEQ74537.1 - 0.032 13.6 1.9 0.11 11.9 0.4 2.2 2 0 0 2 2 2 0 Foie gras liver health family 1 TPR_6 PF13174.1 EEQ74537.1 - 0.14 12.6 2.3 47 4.7 0.0 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EEQ74537.1 - 0.99 10.0 7.8 1.3 9.6 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat Gln-synt_C PF00120.19 EEQ74538.1 - 7.1e-37 126.9 0.0 2.3e-36 125.2 0.0 1.7 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EEQ74538.1 - 0.011 15.3 0.0 4.3 6.9 0.0 2.8 2 0 0 2 2 2 0 Glutamine synthetase, beta-Grasp domain OPT PF03169.10 EEQ74539.1 - 8.3e-107 358.1 24.7 1.9e-106 356.9 17.1 1.5 1 1 0 1 1 1 1 OPT oligopeptide transporter protein CorA PF01544.13 EEQ74540.1 - 4.1e-13 49.0 0.1 6.3e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein MscS_TM PF12794.2 EEQ74540.1 - 0.0016 17.1 0.6 0.0025 16.4 0.4 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 TcpE PF12648.2 EEQ74540.1 - 0.13 12.3 0.9 0.25 11.5 0.6 1.3 1 0 0 1 1 1 0 TcpE family zf-Apc11 PF12861.2 EEQ74542.1 - 1.4e-25 88.9 1.9 1.9e-25 88.5 1.3 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EEQ74542.1 - 3.1e-17 62.4 0.6 4.4e-17 61.9 0.4 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-HIT PF04438.11 EEQ74542.1 - 0.054 13.1 1.1 0.1 12.2 0.8 1.5 1 0 0 1 1 1 0 HIT zinc finger Rhodanese PF00581.15 EEQ74543.1 - 1.2e-19 70.6 0.0 3.7e-09 36.9 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Ribosom_S12_S23 PF00164.20 EEQ74543.1 - 5.5e-05 22.5 0.0 9.2e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S12/S23 PIN_4 PF13638.1 EEQ74544.1 - 2.2e-05 24.5 0.0 0.0059 16.7 0.0 2.7 2 1 0 2 2 2 2 PIN domain Borealin PF10512.4 EEQ74544.1 - 0.026 14.4 0.1 0.26 11.2 0.1 2.3 2 0 0 2 2 2 0 Cell division cycle-associated protein 8 LacI PF00356.16 EEQ74545.1 - 0.072 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family PRTP PF01366.13 EEQ74546.1 - 0.028 12.4 1.8 0.033 12.1 1.2 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein BRE1 PF08647.6 EEQ74546.1 - 0.07 13.1 2.4 0.078 12.9 1.7 1.1 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase PINIT PF14324.1 EEQ74546.1 - 0.13 12.3 0.4 0.16 12.0 0.3 1.1 1 0 0 1 1 1 0 PINIT domain Translin PF01997.11 EEQ74547.1 - 1.3e-68 230.5 0.0 1.5e-68 230.3 0.0 1.0 1 0 0 1 1 1 1 Translin family RPEL PF02755.10 EEQ74548.1 - 4.2e-26 89.5 17.9 4.3e-10 38.5 1.0 3.4 3 0 0 3 3 3 3 RPEL repeat Rotamase_3 PF13616.1 EEQ74548.1 - 0.0028 17.9 0.1 0.0052 17.0 0.1 1.5 1 1 1 2 2 2 1 PPIC-type PPIASE domain CP12 PF02672.10 EEQ74548.1 - 0.19 12.2 4.7 5.8 7.4 0.3 2.5 3 0 0 3 3 3 0 CP12 domain MCPVI PF02993.9 EEQ74548.1 - 1.6 8.8 4.4 1.7 8.7 2.0 1.4 1 1 0 1 1 1 0 Minor capsid protein VI UPF0183 PF03676.9 EEQ74549.1 - 1.6e-37 129.0 0.0 6e-28 97.5 0.0 4.1 4 0 0 4 4 4 4 Uncharacterised protein family (UPF0183) Methyltransf_12 PF08242.7 EEQ74550.1 - 0.035 14.5 0.1 1.4 9.4 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain DMPK_coil PF08826.5 EEQ74550.1 - 0.067 13.0 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 DMPK coiled coil domain like Kinesin PF00225.18 EEQ74551.1 - 4.6e-109 364.1 0.1 8.7e-109 363.2 0.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bind PF13931.1 EEQ74551.1 - 2e-10 41.0 1.3 2e-10 41.0 0.9 4.5 3 2 2 5 5 5 1 Kinesin-associated microtubule-binding Tmp39 PF10271.4 EEQ74551.1 - 0.24 10.0 0.1 0.4 9.2 0.1 1.3 1 0 0 1 1 1 0 Putative transmembrane protein F-box-like PF12937.2 EEQ74552.1 - 0.00068 19.3 0.0 0.0038 16.9 0.0 2.4 2 1 0 2 2 2 1 F-box-like Mannosyl_trans PF05007.8 EEQ74553.1 - 6.1e-76 255.4 15.4 1.1e-75 254.6 10.7 1.4 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EEQ74553.1 - 7.2e-05 21.8 5.7 7.2e-05 21.8 3.9 3.2 2 1 1 3 3 3 2 GPI transamidase subunit PIG-U DUF3985 PF13153.1 EEQ74554.1 - 0.032 14.0 0.9 0.056 13.2 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3985) FHA PF00498.21 EEQ74555.1 - 3.2e-07 30.3 1.3 6.7e-07 29.3 0.4 1.9 2 0 0 2 2 2 1 FHA domain IMS PF00817.15 EEQ74556.1 - 9.6e-39 132.5 0.1 1.7e-38 131.7 0.1 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EEQ74556.1 - 4.2e-15 55.7 0.3 8.6e-15 54.7 0.2 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EEQ74556.1 - 1.3e-05 24.9 0.0 4e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif zf-Sec23_Sec24 PF04810.10 EEQ74556.1 - 0.021 14.4 0.1 0.051 13.1 0.1 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger DnaJ-X PF14308.1 EEQ74558.1 - 7e-70 234.4 1.2 7e-70 234.4 0.8 2.6 2 1 0 2 2 2 2 X-domain of DnaJ-containing DnaJ PF00226.26 EEQ74558.1 - 2.9e-26 90.9 0.2 7.1e-26 89.7 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain HisG_C PF08029.6 EEQ74558.1 - 0.0017 18.2 0.1 0.0033 17.3 0.1 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain SQS_PSY PF00494.14 EEQ74559.1 - 3.6e-44 151.0 0.0 1.7e-43 148.8 0.0 1.8 2 0 0 2 2 2 1 Squalene/phytoene synthase Cytochrom_B_N PF00033.14 EEQ74559.1 - 0.052 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Herpes_gE PF02480.11 EEQ74559.1 - 0.067 11.4 0.0 0.1 10.8 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Ni_hydr_CYTB PF01292.15 EEQ74559.1 - 0.095 12.0 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF2207 PF09972.4 EEQ74559.1 - 0.16 10.5 0.0 0.27 9.7 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Fungal_trans PF04082.13 EEQ74560.1 - 2.2e-15 56.2 0.0 3.9e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain tRNA-synt_1 PF00133.17 EEQ74561.1 - 2.4e-164 547.6 0.0 3.5e-164 547.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EEQ74561.1 - 2.4e-23 82.6 0.7 4.4e-23 81.7 0.5 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EEQ74561.1 - 6.4e-21 74.4 0.1 9.1e-11 41.0 0.0 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EEQ74561.1 - 0.02 14.1 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.9 EEQ74561.1 - 0.02 14.5 2.6 0.05 13.2 1.8 1.8 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS tRNA-synt_1d PF00750.14 EEQ74561.1 - 0.035 12.9 0.0 0.14 10.9 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 EEQ74561.1 - 0.081 12.0 0.0 11 5.0 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Bac_rhodopsin PF01036.13 EEQ74563.1 - 6.5e-39 133.5 18.8 8e-39 133.2 13.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein YibE_F PF07907.6 EEQ74563.1 - 0.0032 16.6 6.8 0.0032 16.6 4.7 2.1 2 0 0 2 2 2 1 YibE/F-like protein Wzy_C PF04932.10 EEQ74563.1 - 0.014 15.1 1.5 0.014 15.1 1.0 2.6 1 1 1 2 2 2 0 O-Antigen ligase DUF788 PF05620.6 EEQ74563.1 - 0.97 9.2 4.7 1.2 8.9 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF788) DUF3792 PF12670.2 EEQ74563.1 - 3.1 7.6 18.2 5.3 6.9 1.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) Med3 PF11593.3 EEQ74564.1 - 3.8 6.6 17.0 7.1 5.7 11.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_S5 PF00333.15 EEQ74565.1 - 2.3e-28 97.6 3.2 2.5e-28 97.6 1.4 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EEQ74565.1 - 3.4e-22 77.4 0.0 6.4e-22 76.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Mpv17_PMP22 PF04117.7 EEQ74566.1 - 2.8e-25 87.7 2.6 4.1e-25 87.2 1.8 1.2 1 0 0 1 1 1 1 Mpv17 / PMP22 family IF4E PF01652.13 EEQ74567.1 - 2e-59 199.8 0.4 2.4e-59 199.5 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AMP-binding PF00501.23 EEQ74568.1 - 1e-65 221.7 0.0 1.5e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ74568.1 - 2.3e-11 44.4 0.0 5.3e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BolA PF01722.13 EEQ74569.1 - 1.5e-26 92.1 1.8 1.8e-26 91.9 1.3 1.1 1 0 0 1 1 1 1 BolA-like protein Queuosine_synth PF02547.10 EEQ74569.1 - 0.022 13.5 0.1 0.022 13.4 0.1 1.0 1 0 0 1 1 1 0 Queuosine biosynthesis protein SNARE PF05739.14 EEQ74570.1 - 1.6e-11 43.7 7.7 2.4e-11 43.1 3.6 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EEQ74570.1 - 6.5e-08 32.6 0.5 6.5e-08 32.6 0.4 2.5 2 1 0 2 2 2 1 Syntaxin Gp-FAR-1 PF05823.7 EEQ74570.1 - 1.2e-05 25.2 3.0 1.4e-05 25.0 0.2 2.1 1 1 1 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Synaptobrevin PF00957.16 EEQ74570.1 - 0.00077 19.0 1.2 0.00077 19.0 0.8 2.3 3 0 0 3 3 3 1 Synaptobrevin DUF912 PF06024.7 EEQ74570.1 - 0.0059 16.6 0.1 0.016 15.2 0.1 1.7 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) MCPsignal PF00015.16 EEQ74570.1 - 0.0079 15.7 8.2 0.016 14.7 3.3 2.3 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain zf-CpG_bind_C PF12269.3 EEQ74570.1 - 0.013 14.9 9.3 0.039 13.4 0.4 2.2 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain COG5 PF10392.4 EEQ74570.1 - 0.015 15.2 2.3 2 8.3 0.1 2.7 2 1 0 2 2 2 0 Golgi transport complex subunit 5 Laminin_II PF06009.7 EEQ74570.1 - 0.023 14.4 6.3 0.32 10.7 0.3 2.5 2 0 0 2 2 2 0 Laminin Domain II PBP1_TM PF14812.1 EEQ74570.1 - 0.051 13.8 0.7 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PTA_PTB PF01515.14 EEQ74570.1 - 0.051 12.6 1.9 0.097 11.7 1.3 1.4 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase BLOC1_2 PF10046.4 EEQ74570.1 - 0.061 13.4 7.0 0.49 10.5 0.6 3.2 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1542 PF07564.6 EEQ74570.1 - 0.85 9.6 9.6 10 6.2 0.0 4.0 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1542) Spectrin PF00435.16 EEQ74570.1 - 0.85 9.9 10.4 0.77 10.0 0.2 3.0 2 1 1 3 3 3 0 Spectrin repeat GrpE PF01025.14 EEQ74570.1 - 1.4 8.4 8.1 0.15 11.6 0.8 2.1 1 1 1 2 2 2 0 GrpE HisKA_3 PF07730.8 EEQ74570.1 - 2 8.8 8.0 4.9 7.5 0.1 4.1 3 1 2 5 5 5 0 Histidine kinase TBPIP PF07106.8 EEQ74570.1 - 7.4 6.0 10.1 1.3 8.5 2.9 2.4 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SlyX PF04102.7 EEQ74570.1 - 8.9 6.7 12.5 1.3 9.5 2.6 3.6 1 1 1 4 4 4 0 SlyX NAPRTase PF04095.11 EEQ74572.1 - 7.8e-49 166.1 0.2 4.2e-25 88.4 0.2 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family adh_short PF00106.20 EEQ74575.1 - 2.2e-15 56.9 0.3 3.5e-15 56.2 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ74575.1 - 1.3e-09 37.9 0.1 2.2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEQ74575.1 - 0.00019 21.3 0.0 0.00029 20.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EEQ74575.1 - 0.012 15.0 0.0 0.048 13.0 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RtcR PF06956.6 EEQ74575.1 - 0.047 13.0 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase Eno-Rase_NADH_b PF12242.3 EEQ74575.1 - 0.075 12.8 0.1 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Zn_clus PF00172.13 EEQ74576.1 - 1.2e-06 28.3 8.9 2.1e-06 27.5 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain dCMP_cyt_deam_1 PF00383.17 EEQ74576.1 - 0.16 11.6 2.1 0.31 10.6 1.4 1.4 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Dickkopf_N PF04706.7 EEQ74576.1 - 2.5 8.3 15.0 2.8 8.1 5.2 2.3 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Tom37_C PF11801.3 EEQ74578.1 - 2.4e-43 147.9 0.1 2.3e-41 141.4 0.0 2.2 2 0 0 2 2 2 1 Tom37 C-terminal domain Tom37 PF10568.4 EEQ74578.1 - 8.2e-28 96.4 0.0 1.2e-26 92.7 0.0 2.5 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein SpoIIIAH PF12685.2 EEQ74578.1 - 0.02 14.3 0.5 0.037 13.5 0.4 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein GST_C_2 PF13410.1 EEQ74578.1 - 0.026 14.4 0.4 0.055 13.3 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF2457 PF10446.4 EEQ74578.1 - 0.034 12.8 1.5 0.059 12.0 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ATP-synt_E PF05680.7 EEQ74578.1 - 0.09 12.7 0.6 0.2 11.6 0.4 1.5 1 0 0 1 1 1 0 ATP synthase E chain Nop14 PF04147.7 EEQ74578.1 - 0.27 9.0 4.4 0.36 8.6 3.0 1.1 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.17 EEQ74579.1 - 1e-58 198.8 15.5 4.5e-57 193.4 10.8 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter AMP-binding PF00501.23 EEQ74581.1 - 1.9e-76 257.1 0.0 2.8e-76 256.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme COX6B PF02297.12 EEQ74583.1 - 0.039 13.9 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb EMP70 PF02990.11 EEQ74586.1 - 3.9e-179 596.4 0.5 4.7e-179 596.1 0.4 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Med21 PF11221.3 EEQ74586.1 - 0.24 11.3 0.0 0.36 10.7 0.0 1.2 1 0 0 1 1 1 0 Subunit 21 of Mediator complex RabGAP-TBC PF00566.13 EEQ74587.1 - 4.4e-48 163.5 0.0 2.9e-47 160.9 0.0 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain FANCI_S4 PF14678.1 EEQ74587.1 - 0.027 13.5 0.6 0.76 8.8 0.0 2.6 3 0 0 3 3 3 0 FANCI solenoid 4 F-box PF00646.28 EEQ74588.1 - 0.00071 19.1 0.0 0.0021 17.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EEQ74588.1 - 0.0041 16.8 1.5 0.015 15.0 0.0 2.4 2 0 0 2 2 2 1 F-box-like MFS_1 PF07690.11 EEQ74589.1 - 2.7e-25 88.8 17.4 2.7e-25 88.8 12.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 EEQ74590.1 - 7.4e-13 47.9 7.8 7.4e-13 47.9 5.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Med4 PF10018.4 EEQ74591.1 - 2.6e-29 101.9 0.0 4.9e-29 101.0 0.0 1.4 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 EF-hand_7 PF13499.1 EEQ74592.1 - 6.2e-29 99.9 8.4 1e-13 51.2 0.2 3.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EEQ74592.1 - 1.6e-24 83.3 10.3 4.3e-08 31.8 0.1 4.7 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 EEQ74592.1 - 3.1e-24 82.6 2.4 3.9e-05 23.1 0.1 5.2 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 EEQ74592.1 - 4.5e-17 60.5 10.4 4.5e-05 22.5 0.0 4.8 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 EEQ74592.1 - 1.3e-15 56.7 12.1 2.8e-05 23.6 1.3 4.4 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 EEQ74592.1 - 9.9e-09 34.8 5.0 0.0012 18.5 0.1 3.6 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EEQ74592.1 - 0.00066 19.5 0.5 0.21 11.5 0.0 3.4 2 1 1 3 3 3 1 EF-hand domain EF-hand_10 PF14788.1 EEQ74592.1 - 0.0044 16.6 1.4 1.9 8.2 0.0 3.7 4 0 0 4 4 4 1 EF hand SPARC_Ca_bdg PF10591.4 EEQ74592.1 - 0.028 14.4 1.1 0.9 9.5 0.0 3.0 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.6 EEQ74592.1 - 0.044 12.4 0.4 2.6 6.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EF-hand_2 PF09068.6 EEQ74592.1 - 0.066 13.2 0.1 6.9 6.7 0.0 3.1 3 1 0 3 3 3 0 EF hand DAG_kinase_N PF14513.1 EEQ74592.1 - 0.093 12.9 1.7 0.28 11.3 0.9 1.7 1 1 1 2 2 2 0 Diacylglycerol kinase N-terminus S10_plectin PF03501.10 EEQ74592.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain DNA_topoisoIV PF00521.15 EEQ74593.1 - 3.3e-125 418.2 0.1 6.2e-125 417.3 0.1 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EEQ74593.1 - 4.6e-34 117.1 3.8 1.1e-33 115.8 2.6 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EEQ74593.1 - 4.5e-12 45.8 5.3 5.6e-12 45.5 0.0 3.5 4 0 0 4 4 4 1 Toprim domain HATPase_c PF02518.21 EEQ74593.1 - 5.4e-11 42.1 0.0 2.1e-10 40.3 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Reticulon PF02453.12 EEQ74596.1 - 2.5e-38 131.3 4.1 3.6e-38 130.8 2.8 1.2 1 0 0 1 1 1 1 Reticulon DUF3375 PF11855.3 EEQ74596.1 - 0.021 13.6 1.3 0.031 13.0 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) Apolipoprotein PF01442.13 EEQ74596.1 - 0.027 13.9 0.3 0.044 13.2 0.2 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Pex24p PF06398.6 EEQ74596.1 - 0.052 12.3 3.7 0.071 11.9 2.6 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Cytochrome-c551 PF10643.4 EEQ74596.1 - 0.14 11.4 1.7 0.25 10.6 1.2 1.6 1 1 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Acyl-CoA_dh_1 PF00441.19 EEQ74597.1 - 3.3e-32 111.6 2.0 3.3e-32 111.6 1.4 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EEQ74597.1 - 8.5e-22 77.8 0.2 2.3e-21 76.4 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EEQ74597.1 - 3.9e-17 62.7 1.1 3.9e-17 62.7 0.7 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain INCENP_ARK-bind PF03941.10 EEQ74598.1 - 1.2e-21 76.2 0.9 5.7e-21 74.1 0.6 2.3 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region CAF-1_p150 PF11600.3 EEQ74598.1 - 0.0021 17.4 28.1 0.0021 17.4 19.5 5.1 5 1 0 5 5 5 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ank_2 PF12796.2 EEQ74603.1 - 1.7e-102 335.9 25.8 4.7e-18 65.3 0.2 6.0 3 1 5 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ74603.1 - 5.3e-57 186.9 32.9 1.1e-05 24.9 0.0 13.8 14 0 0 14 14 14 10 Ankyrin repeat Ank_4 PF13637.1 EEQ74603.1 - 1.6e-43 146.2 6.1 1.1e-06 29.0 0.0 9.6 5 2 5 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ74603.1 - 9.6e-42 136.8 8.3 0.0005 20.0 0.0 13.0 13 0 0 13 13 13 9 Ankyrin repeat Ank_5 PF13857.1 EEQ74603.1 - 5.6e-38 128.1 13.2 0.00016 21.8 0.1 10.0 2 2 9 11 11 11 8 Ankyrin repeats (many copies) NACHT PF05729.7 EEQ74603.1 - 8.1e-09 35.3 0.0 1.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EEQ74603.1 - 0.0004 20.4 0.0 0.0029 17.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EEQ74603.1 - 0.00097 19.0 0.0 0.026 14.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_9 PF12781.2 EEQ74603.1 - 0.018 13.9 0.1 0.13 11.0 0.1 2.2 2 0 0 2 2 2 0 ATP-binding dynein motor region D5 DUF1843 PF08898.5 EEQ74603.1 - 0.082 12.9 3.2 33 4.6 0.0 4.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) PDZ_1 PF12812.2 EEQ74604.1 - 1.1e-52 175.8 0.1 3.8e-33 113.2 0.0 3.0 3 0 0 3 3 3 2 PDZ-like domain PDZ_2 PF13180.1 EEQ74604.1 - 5.3e-15 55.0 0.1 4.2e-06 26.5 0.0 4.0 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.1 EEQ74604.1 - 2.4e-14 53.3 0.2 8.5e-14 51.5 0.0 2.0 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ PF00595.19 EEQ74604.1 - 4.5e-12 45.9 0.0 1.2e-05 25.4 0.0 3.6 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 EEQ74604.1 - 4.4e-06 26.3 0.1 0.03 14.1 0.0 3.7 3 0 0 3 3 3 2 Tricorn protease PDZ domain Trypsin PF00089.21 EEQ74604.1 - 6.7e-06 25.8 0.0 2.2e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Trypsin Peptidase_S7 PF00949.16 EEQ74604.1 - 0.064 12.6 0.1 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.11 EEQ74604.1 - 0.097 11.9 0.2 0.15 11.3 0.2 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S46 PF10459.4 EEQ74604.1 - 0.16 10.3 0.4 0.31 9.4 0.1 1.5 2 0 0 2 2 2 0 Peptidase S46 SSXT PF05030.7 EEQ74605.1 - 9.5e-05 21.9 0.1 0.59 9.7 0.0 2.6 2 0 0 2 2 2 2 SSXT protein (N-terminal region) TPR_11 PF13414.1 EEQ74606.1 - 1.4e-11 43.8 0.4 6e-08 32.2 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EEQ74606.1 - 3.2e-07 29.6 1.4 0.019 14.5 0.3 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ74606.1 - 0.0015 18.8 0.1 0.0048 17.1 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ74606.1 - 0.0082 15.9 1.2 8.1 6.6 0.0 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat Pox_T4_N PF04491.7 EEQ74606.1 - 0.036 13.8 0.1 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 Poxvirus T4 protein, N terminus TPR_16 PF13432.1 EEQ74606.1 - 0.066 13.9 0.0 0.22 12.2 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3808 PF10300.4 EEQ74606.1 - 0.076 11.5 0.2 0.11 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) FSH1 PF03959.8 EEQ74607.1 - 5.2e-28 97.9 0.0 1.1e-27 96.8 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EEQ74607.1 - 1e-10 41.9 0.2 6.7e-05 22.8 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ74607.1 - 1.8e-06 27.8 0.0 3.6e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EEQ74607.1 - 0.004 16.6 0.1 0.83 9.0 0.0 2.9 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EEQ74607.1 - 0.0058 16.2 0.8 2.6 7.5 0.1 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.13 EEQ74607.1 - 0.009 15.3 0.0 0.14 11.3 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF2048 PF09752.4 EEQ74607.1 - 0.014 14.3 0.1 0.022 13.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) F-box-like PF12937.2 EEQ74608.1 - 2.2e-05 24.0 1.3 0.023 14.3 0.2 2.6 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 EEQ74608.1 - 0.12 12.0 0.6 18 5.1 0.1 2.7 2 0 0 2 2 2 0 F-box domain HR1 PF02185.11 EEQ74609.1 - 0.0027 17.4 4.6 0.0071 16.0 3.2 1.7 1 0 0 1 1 1 1 Hr1 repeat Laminin_II PF06009.7 EEQ74609.1 - 0.0036 17.0 1.3 0.0065 16.2 0.3 1.7 1 1 0 2 2 2 1 Laminin Domain II DUF3584 PF12128.3 EEQ74609.1 - 0.012 13.0 1.4 0.013 12.8 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IncA PF04156.9 EEQ74609.1 - 0.019 14.5 1.1 0.025 14.2 0.8 1.2 1 0 0 1 1 1 0 IncA protein CPSase_L_D3 PF02787.14 EEQ74609.1 - 0.023 14.4 0.9 0.04 13.6 0.6 1.4 1 1 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain DUF1664 PF07889.7 EEQ74609.1 - 0.097 12.4 1.6 0.14 11.9 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.3 EEQ74609.1 - 0.1 12.3 9.4 0.15 11.8 3.3 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF641 PF04859.7 EEQ74609.1 - 0.17 11.6 4.1 0.14 11.8 1.7 1.7 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) APG6 PF04111.7 EEQ74609.1 - 0.19 10.7 2.2 0.24 10.4 1.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Phage_GP20 PF06810.6 EEQ74609.1 - 0.21 11.0 2.9 0.55 9.6 2.0 1.8 1 1 0 1 1 1 0 Phage minor structural protein GP20 DUF2937 PF11157.3 EEQ74609.1 - 0.31 10.3 3.3 0.12 11.7 0.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) SlyX PF04102.7 EEQ74609.1 - 0.33 11.3 5.9 0.38 11.1 1.5 2.3 1 1 1 2 2 2 0 SlyX FlaC_arch PF05377.6 EEQ74609.1 - 0.71 9.8 3.3 14 5.6 0.1 2.6 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) CENP-Q PF13094.1 EEQ74609.1 - 4.9 7.1 8.1 8.7 6.3 5.0 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Sugarporin_N PF11471.3 EEQ74609.1 - 6.6 6.4 14.5 1.6 8.4 0.1 3.3 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension DASH_Spc34 PF08657.5 EEQ74609.1 - 7.1 6.2 8.5 9.2 5.8 5.9 1.5 1 1 0 1 1 1 0 DASH complex subunit Spc34 Val_tRNA-synt_C PF10458.4 EEQ74609.1 - 7.9 6.6 12.7 0.29 11.2 1.5 2.7 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm peroxidase PF00141.18 EEQ74610.1 - 4.3e-40 137.6 0.0 6.4e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF4360 PF14273.1 EEQ74612.1 - 2.9e-30 105.2 0.3 3.4e-30 105.0 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Pyridoxal_deC PF00282.14 EEQ74613.1 - 2.9e-08 32.5 0.1 0.00043 18.8 0.0 2.3 1 1 1 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain HC2 PF07382.6 EEQ74614.1 - 7.2e-05 22.7 42.2 0.00021 21.2 16.0 3.5 3 1 1 4 4 4 2 Histone H1-like nucleoprotein HC2 SBDS_C PF09377.5 EEQ74616.1 - 9.9e-46 154.5 0.0 1.4e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EEQ74616.1 - 2.2e-27 94.6 0.1 3.9e-27 93.8 0.1 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Peptidase_S10 PF00450.17 EEQ74619.1 - 1.2e-130 436.4 0.0 1.4e-130 436.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EEQ74619.1 - 0.00076 19.4 0.0 0.01 15.7 0.0 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Carbpep_Y_N PF05388.6 EEQ74619.1 - 0.0067 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Ribosomal_S13 PF00416.17 EEQ74620.1 - 1.3e-41 141.3 2.8 1.6e-41 141.0 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EEQ74620.1 - 0.014 13.9 0.1 0.016 13.7 0.0 1.3 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 EEQ74620.1 - 0.1 12.6 0.4 0.32 11.0 0.0 2.0 2 1 0 2 2 2 0 Helix-hairpin-helix motif zf-RING_2 PF13639.1 EEQ74622.1 - 4.5e-13 48.7 8.3 8.6e-13 47.8 5.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EEQ74622.1 - 8e-08 31.8 6.6 1.4e-07 30.9 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ74622.1 - 3.8e-07 29.7 5.2 6.9e-07 28.9 3.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEQ74622.1 - 4.9e-07 29.6 7.5 9.1e-07 28.8 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ74622.1 - 1.2e-06 28.0 4.4 2.1e-06 27.3 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEQ74622.1 - 2.4e-06 27.5 7.4 5.5e-06 26.3 5.1 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EEQ74622.1 - 2.6e-06 27.1 2.0 6.2e-06 25.9 1.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EEQ74622.1 - 0.0058 16.1 5.1 0.011 15.2 3.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 EEQ74622.1 - 0.022 14.2 3.2 0.037 13.5 2.2 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 EEQ74622.1 - 0.12 12.4 6.8 0.11 12.5 3.4 2.0 2 1 0 2 2 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 EEQ74622.1 - 0.16 11.8 5.3 0.19 11.5 2.6 2.0 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.6 EEQ74622.1 - 0.17 11.8 4.1 0.41 10.6 2.9 1.7 1 1 0 1 1 1 0 RING-like domain zf-RING_UBOX PF13445.1 EEQ74622.1 - 0.18 11.5 4.6 0.88 9.3 3.1 2.3 1 1 1 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 EEQ74622.1 - 1.9 8.4 6.0 8.3 6.4 4.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Mannosyl_trans2 PF04188.8 EEQ74624.1 - 7.1e-50 170.2 3.6 9.1e-50 169.8 2.5 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) DUF3437 PF11919.3 EEQ74625.1 - 1.2e-30 105.0 0.0 3.1e-30 103.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 EEQ74625.1 - 0.00021 21.1 0.1 0.75 10.0 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat CLASP_N PF12348.3 EEQ74625.1 - 0.00054 19.3 0.4 0.013 14.9 0.0 2.9 2 0 0 2 2 2 1 CLASP N terminal V_ATPase_I PF01496.14 EEQ74626.1 - 4e-296 983.9 0.7 4.6e-296 983.7 0.5 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Filament PF00038.16 EEQ74626.1 - 0.96 8.8 4.6 8.6 5.7 0.0 2.4 2 1 0 2 2 2 0 Intermediate filament protein PQQ_2 PF13360.1 EEQ74627.1 - 0.02 14.3 0.0 2.5 7.4 0.0 2.1 1 1 0 2 2 2 0 PQQ-like domain adh_short PF00106.20 EEQ74628.1 - 2.5e-31 108.8 0.4 3.1e-31 108.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ74628.1 - 6.4e-19 68.6 0.0 8.4e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ74628.1 - 1.7e-14 53.9 0.7 2.7e-14 53.2 0.5 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EEQ74628.1 - 4.8e-07 29.4 0.1 7.7e-07 28.7 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EEQ74628.1 - 6.3e-05 22.6 0.6 0.00016 21.3 0.4 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EEQ74628.1 - 0.0016 17.5 0.2 0.029 13.4 0.0 2.5 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.12 EEQ74628.1 - 0.0032 16.3 2.5 0.016 14.0 1.0 2.3 2 1 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EEQ74628.1 - 0.014 15.3 0.2 0.062 13.2 0.1 1.9 2 0 0 2 2 2 0 NADH(P)-binding Glyco_transf_5 PF08323.6 EEQ74628.1 - 0.022 14.2 0.0 0.073 12.5 0.0 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain F420_oxidored PF03807.12 EEQ74628.1 - 0.048 14.0 0.9 0.6 10.5 0.2 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DFP PF04127.10 EEQ74628.1 - 0.14 11.8 1.0 0.28 10.7 0.3 1.8 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein NMO PF03060.10 EEQ74629.1 - 0.28 10.2 0.2 0.59 9.2 0.1 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase Aha1_N PF09229.6 EEQ74630.1 - 5.9e-39 133.0 1.0 9.4e-39 132.3 0.7 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EEQ74630.1 - 9.5e-16 58.0 0.2 1.9e-15 57.0 0.1 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Alpha-amylase PF00128.19 EEQ74631.1 - 1.6e-62 211.7 0.0 2.2e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EEQ74631.1 - 1e-31 108.8 0.0 2.7e-31 107.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Glyco_hydro_31 PF01055.21 EEQ74631.1 - 5.4e-05 22.1 0.2 5.7e-05 22.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF187 PF02638.10 EEQ74631.1 - 0.01 14.7 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 Glyco_hydro_70 PF02324.11 EEQ74631.1 - 0.027 12.2 0.0 0.049 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 YTH PF04146.10 EEQ74632.1 - 9.2e-27 93.3 0.0 2.4e-26 92.0 0.0 1.7 2 0 0 2 2 2 1 YT521-B-like domain RRM_1 PF00076.17 EEQ74632.1 - 1.3e-06 27.9 0.0 2.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ74632.1 - 1.3e-06 28.2 0.0 4.1e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ74632.1 - 0.023 14.5 0.1 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ArfGap PF01412.13 EEQ74633.1 - 3.7e-33 113.7 0.0 3.7e-33 113.7 0.0 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 EEQ74633.1 - 2.9e-13 49.9 2.1 3.3e-13 49.7 0.1 2.2 3 0 0 3 3 3 1 PH domain EMP24_GP25L PF01105.19 EEQ74633.1 - 0.18 11.5 2.9 0.63 9.7 1.4 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF3435 PF11917.3 EEQ74634.1 - 9.1e-14 50.9 0.8 1.4e-12 47.0 0.4 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) SRF-TF PF00319.13 EEQ74639.1 - 0.015 14.5 0.0 0.03 13.5 0.0 1.5 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Hydrophob_seed PF14547.1 EEQ74639.1 - 0.13 12.1 0.4 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 Hydrophobic seed protein Pkinase PF00069.20 EEQ74643.1 - 7.1e-15 54.8 0.0 1.6e-13 50.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ74643.1 - 1.7e-06 27.2 0.0 5.4e-05 22.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEQ74643.1 - 0.00032 19.8 0.2 0.00062 18.8 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ74643.1 - 0.0097 15.6 0.0 0.052 13.2 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family PI3_PI4_kinase PF00454.22 EEQ74645.1 - 3.8e-35 121.4 0.0 1.9e-34 119.1 0.0 2.2 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EEQ74645.1 - 4.9e-23 81.2 0.0 1.3e-22 79.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pkinase PF00069.20 EEQ74646.1 - 5.1e-78 261.7 0.0 6.8e-78 261.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ74646.1 - 1.2e-35 122.9 0.0 1.5e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EEQ74646.1 - 9.9e-18 64.0 0.2 2.1e-17 63.0 0.1 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EEQ74646.1 - 1.8e-08 33.7 0.0 7.2e-08 31.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEQ74646.1 - 0.00056 19.7 0.2 0.0043 16.8 0.2 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EEQ74646.1 - 0.027 13.2 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EEQ74646.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family p450 PF00067.17 EEQ74647.1 - 7.5e-71 239.0 0.0 9.6e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3684 PF12449.3 EEQ74647.1 - 0.021 12.4 0.0 0.03 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) PgaD PF13994.1 EEQ74647.1 - 0.15 11.5 0.4 0.81 9.1 0.2 2.1 2 0 0 2 2 2 0 PgaD-like protein IGR PF09597.5 EEQ74648.1 - 2.9e-20 71.9 0.1 4.7e-20 71.2 0.1 1.3 1 0 0 1 1 1 1 IGR protein motif PX PF00787.19 EEQ74648.1 - 0.14 11.9 0.4 0.3 10.9 0.2 1.5 1 0 0 1 1 1 0 PX domain Pkinase PF00069.20 EEQ74649.1 - 1.7e-62 210.9 0.0 2e-62 210.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ74649.1 - 2.2e-33 115.4 0.0 3.1e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ74649.1 - 0.061 13.0 0.2 0.12 12.1 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EEQ74649.1 - 0.12 11.2 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like C2 PF00168.25 EEQ74650.1 - 2.6e-09 36.7 0.0 6.4e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain ABC1 PF03109.11 EEQ74651.1 - 8.4e-18 64.4 3.4 2.3e-11 43.7 0.1 3.7 2 1 1 3 3 3 2 ABC1 family APH PF01636.18 EEQ74651.1 - 0.0036 17.0 1.7 0.017 14.8 0.4 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family EthD PF07110.6 EEQ74652.1 - 1.5e-14 54.7 0.3 2.2e-14 54.1 0.2 1.3 1 0 0 1 1 1 1 EthD domain DUF3788 PF12663.2 EEQ74654.1 - 0.046 13.3 0.2 0.21 11.2 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3788) Kinesin PF00225.18 EEQ74655.1 - 1.3e-92 310.0 0.3 2.4e-92 309.1 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain DAGAT PF03982.8 EEQ74657.1 - 1.6e-93 312.6 0.0 2.1e-93 312.2 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.8 EEQ74657.1 - 0.082 12.4 2.2 0.15 11.6 1.5 1.3 1 0 0 1 1 1 0 Rer1 family Gag_p6 PF08705.6 EEQ74658.1 - 0.00076 19.4 2.4 0.067 13.2 0.1 2.6 2 0 0 2 2 2 2 Gag protein p6 Surp PF01805.15 EEQ74658.1 - 0.098 12.3 0.5 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Surp module G-patch PF01585.18 EEQ74659.1 - 5.2e-05 22.9 0.1 0.00048 19.8 0.0 2.5 1 1 0 1 1 1 1 G-patch domain MIP-T3 PF10243.4 EEQ74659.1 - 0.4 9.0 40.3 0.61 8.4 28.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF966 PF06136.8 EEQ74659.1 - 0.67 9.3 21.8 0.99 8.7 15.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PLRV_ORF5 PF01690.12 EEQ74659.1 - 1.4 7.9 18.7 1.7 7.6 13.0 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SOBP PF15279.1 EEQ74659.1 - 2.6 8.3 11.2 3.7 7.8 7.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein FAM75 PF14650.1 EEQ74659.1 - 5.9 6.1 16.4 9 5.5 11.3 1.2 1 0 0 1 1 1 0 FAM75 family ACOX PF01756.14 EEQ74660.1 - 0.0063 15.9 1.1 0.008 15.5 0.8 1.1 1 0 0 1 1 1 1 Acyl-CoA oxidase Atg14 PF10186.4 EEQ74660.1 - 0.0097 14.8 5.7 0.011 14.6 4.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 FCH PF00611.18 EEQ74660.1 - 0.024 14.8 3.7 0.063 13.4 0.2 2.1 1 1 1 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Pilus_CpaD PF09476.5 EEQ74660.1 - 0.034 13.6 3.0 0.28 10.6 1.1 2.0 1 1 1 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) DUF2365 PF10157.4 EEQ74660.1 - 0.035 13.9 0.3 0.058 13.2 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) eIF3_N PF09440.5 EEQ74660.1 - 0.053 13.6 0.6 0.066 13.3 0.4 1.2 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain MADF_DNA_bdg PF10545.4 EEQ74660.1 - 0.069 13.3 2.3 0.094 12.9 1.1 1.6 1 1 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like U3_assoc_6 PF08640.6 EEQ74660.1 - 0.12 12.1 1.9 0.18 11.5 0.1 2.1 1 1 1 2 2 2 0 U3 small nucleolar RNA-associated protein 6 NAAA-beta PF15508.1 EEQ74660.1 - 0.16 12.3 0.5 0.24 11.7 0.3 1.3 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase ALMT PF11744.3 EEQ74660.1 - 0.23 10.0 2.0 0.25 9.9 1.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Syja_N PF02383.13 EEQ74661.1 - 1.3e-81 273.8 0.0 1.8e-81 273.3 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EEQ74661.1 - 2.6e-27 96.3 0.6 4.4e-27 95.6 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Asp-B-Hydro_N PF05279.6 EEQ74662.1 - 2.8 7.7 19.9 4.6 7.0 13.8 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TPR_17 PF13431.1 EEQ74665.1 - 2.9e-06 27.0 0.1 0.00027 20.8 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ74665.1 - 4.4e-06 26.2 1.6 5.9e-05 22.6 0.1 3.2 2 1 1 4 4 4 1 TPR repeat TPR_16 PF13432.1 EEQ74665.1 - 5.2e-06 26.9 1.8 0.67 10.7 0.0 3.7 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ74665.1 - 8.2e-06 26.0 5.4 0.036 14.6 0.1 4.4 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ74665.1 - 4.9e-05 22.7 0.1 0.00043 19.7 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ74665.1 - 0.00012 22.3 0.7 0.049 13.9 0.0 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ74665.1 - 0.001 18.8 1.2 0.028 14.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ74665.1 - 0.0091 15.9 3.1 0.98 9.3 0.0 3.1 1 1 2 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ74665.1 - 0.026 14.2 1.7 1.5 8.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.1 EEQ74665.1 - 0.068 13.4 0.0 0.32 11.3 0.0 2.2 2 0 0 2 2 1 0 Pentatricopeptide repeat domain TPR_9 PF13371.1 EEQ74665.1 - 0.47 10.3 3.2 0.44 10.4 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Adaptin_N PF01602.15 EEQ74666.1 - 1.4e-69 234.8 0.0 2.9e-69 233.8 0.0 1.5 1 1 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 EEQ74666.1 - 9.4e-05 22.1 0.8 4.6 7.5 0.0 4.1 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.2 EEQ74666.1 - 0.023 14.5 1.8 0.61 9.9 0.2 2.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EEQ74666.1 - 0.75 10.3 5.6 4.6 7.8 0.0 4.3 5 0 0 5 5 5 0 HEAT-like repeat RAMP4 PF06624.7 EEQ74667.1 - 0.00032 20.1 0.1 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 IF-2B PF01008.12 EEQ74668.1 - 2.9e-71 239.7 0.6 3.4e-71 239.5 0.4 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family LSM PF01423.17 EEQ74669.1 - 2.8e-15 55.5 0.0 3.5e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEQ74669.1 - 0.0084 16.0 0.1 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF1106 PF06523.6 EEQ74669.1 - 0.092 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1106) Rad60-SLD PF11976.3 EEQ74670.1 - 1.4e-23 82.3 0.0 2.7e-21 75.0 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Trm112p PF03966.11 EEQ74671.1 - 1.6e-17 63.6 0.0 2e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.1 EEQ74671.1 - 0.022 14.9 0.3 0.04 14.1 0.2 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain TF_Zn_Ribbon PF08271.7 EEQ74671.1 - 0.1 11.9 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding N-SET PF11764.3 EEQ74672.1 - 3.3e-53 180.0 0.5 3.3e-53 180.0 0.3 2.8 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 EEQ74672.1 - 2.5e-26 90.7 0.9 5e-26 89.8 0.6 1.6 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 EEQ74672.1 - 4.4e-24 85.6 0.2 4.4e-24 85.6 0.1 3.6 4 2 0 4 4 4 1 SET domain RRM_1 PF00076.17 EEQ74672.1 - 7.8e-05 22.2 0.0 0.00042 19.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PP-binding PF00550.20 EEQ74673.1 - 0.13 12.5 0.1 0.72 10.1 0.0 2.1 1 1 1 2 2 2 0 Phosphopantetheine attachment site SIS PF01380.17 EEQ74675.1 - 1.2e-54 183.4 0.0 3.2e-30 104.3 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EEQ74675.1 - 8.9e-27 93.7 0.0 1.4e-17 63.5 0.0 2.3 1 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EEQ74675.1 - 7.5e-19 67.9 0.0 1.6e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EEQ74675.1 - 1.9e-11 43.7 0.0 4e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EEQ74675.1 - 8.3e-07 27.9 0.0 1.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EEQ74675.1 - 0.03 14.0 0.0 0.29 10.8 0.0 2.4 2 0 0 2 2 2 0 SIS domain DMRL_synthase PF00885.14 EEQ74676.1 - 1.2e-40 138.5 0.1 2.3e-23 82.4 0.0 2.1 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase Proteasome PF00227.21 EEQ74677.1 - 1.6e-46 158.0 0.0 1.1e-32 112.8 0.0 2.3 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EEQ74677.1 - 7.2e-12 44.4 0.9 9.3e-12 44.0 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Zn-ribbon_8 PF09723.5 EEQ74678.1 - 0.038 13.9 0.8 0.092 12.7 0.6 1.6 1 0 0 1 1 1 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 EEQ74678.1 - 0.4 9.9 2.2 0.92 8.7 1.5 1.6 1 1 0 1 1 1 0 zinc-ribbon domain HYLS1_C PF15311.1 EEQ74679.1 - 0.037 14.2 1.7 0.12 12.6 0.3 2.0 2 0 0 2 2 2 0 Hydrolethalus syndrome protein 1 C-terminus MARVEL PF01284.18 EEQ74680.1 - 0.1 12.3 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Membrane-associating domain Iso_dh PF00180.15 EEQ74681.1 - 1.2e-83 281.0 0.0 1.5e-83 280.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase WBS_methylT PF12589.3 EEQ74682.1 - 7.5e-20 71.2 1.4 1.2e-19 70.5 1.0 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EEQ74682.1 - 2.5e-10 40.6 0.0 4.1e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ74682.1 - 4.5e-08 33.3 0.0 9.3e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ74682.1 - 1.6e-05 24.5 0.0 2.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ74682.1 - 2.3e-05 24.1 0.0 3.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ74682.1 - 4.1e-05 24.1 0.0 7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ74682.1 - 6.6e-05 23.3 0.0 0.00018 21.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EEQ74682.1 - 0.0003 20.4 0.0 0.00051 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EEQ74682.1 - 0.00062 19.7 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ74682.1 - 0.0078 15.3 0.0 0.022 13.8 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EEQ74682.1 - 0.059 12.4 0.0 0.15 11.0 0.0 1.6 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase DUF4102 PF13356.1 EEQ74682.1 - 0.1 12.4 0.8 0.41 10.5 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4102) Erv26 PF04148.8 EEQ74683.1 - 1.5e-88 295.7 1.3 1.7e-88 295.4 0.9 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Cytochrom_C_asm PF01578.15 EEQ74683.1 - 0.0038 16.8 0.5 0.0096 15.4 0.1 1.7 1 1 0 1 1 1 1 Cytochrome C assembly protein Ferric_reduct PF01794.14 EEQ74683.1 - 0.03 14.3 3.8 0.27 11.3 2.6 2.3 1 1 0 1 1 1 0 Ferric reductase like transmembrane component RhoGAP PF00620.22 EEQ74686.1 - 1.6e-38 131.6 0.0 3.8e-38 130.5 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EEQ74686.1 - 1e-11 44.9 0.0 3.4e-11 43.2 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EEQ74686.1 - 6e-09 36.1 0.0 1.3e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Rabaptin PF03528.10 EEQ74686.1 - 0.012 15.4 1.3 0.012 15.4 0.9 1.9 2 0 0 2 2 2 0 Rabaptin PH_8 PF15409.1 EEQ74686.1 - 0.016 15.2 0.0 0.08 13.0 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Collagen PF01391.13 EEQ74688.1 - 0.019 14.4 4.9 0.035 13.6 3.4 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) MDM31_MDM32 PF08118.6 EEQ74689.1 - 1.3e-172 574.7 0.5 5.2e-164 546.4 0.0 2.1 1 1 1 2 2 2 2 Yeast mitochondrial distribution and morphology (MDM) proteins TraH_2 PF06871.6 EEQ74689.1 - 0.013 14.9 0.1 0.035 13.5 0.0 1.7 2 0 0 2 2 2 0 TraH_2 KH_1 PF00013.24 EEQ74690.1 - 0.0002 20.9 1.5 0.00033 20.2 0.5 1.7 2 0 0 2 2 2 1 KH domain FNIP_N PF14636.1 EEQ74690.1 - 0.058 13.8 0.1 0.098 13.1 0.1 1.5 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Proteasome PF00227.21 EEQ74691.1 - 4.9e-32 110.7 0.4 9.1e-32 109.8 0.1 1.6 2 0 0 2 2 2 1 Proteasome subunit APH PF01636.18 EEQ74693.1 - 2.8e-16 60.0 0.0 1.1e-15 58.0 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ74693.1 - 0.00016 21.3 0.0 0.00029 20.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase HET PF06985.6 EEQ74694.1 - 6.4e-20 71.7 4.4 3e-17 63.1 0.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ZZ PF00569.12 EEQ74694.1 - 1.1e-13 50.4 25.5 3.3e-07 29.7 5.8 2.6 2 0 0 2 2 2 2 Zinc finger, ZZ type ERp29_N PF07912.8 EEQ74694.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 ERp29, N-terminal domain HCNGP PF07818.8 EEQ74695.1 - 6.1e-33 112.7 0.0 1.2e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 HCNGP-like protein Proteasome PF00227.21 EEQ74696.1 - 3.3e-26 91.7 0.0 3.9e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit FAA_hydrolase PF01557.13 EEQ74697.1 - 2.6e-62 210.1 0.0 3.4e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Complex1_LYR PF05347.10 EEQ74698.1 - 1.4e-15 56.8 2.8 1.6e-15 56.5 2.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EEQ74698.1 - 2.9e-12 46.5 2.7 3.5e-12 46.3 1.8 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EEQ74698.1 - 0.0011 19.4 0.3 0.0014 19.1 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like HSP20 PF00011.16 EEQ74699.1 - 5e-19 68.0 0.0 4.8e-12 45.6 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family Autophagy_act_C PF03987.10 EEQ74701.1 - 0.0084 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain RRM_5 PF13893.1 EEQ74702.1 - 1.3e-09 37.7 0.1 1.8e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEQ74702.1 - 1.2e-08 34.4 0.1 2.5e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ74702.1 - 4.7e-05 23.2 0.0 8.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EEQ74703.1 - 3.5e-19 67.9 10.6 4.5e-07 29.5 0.0 6.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Rax2 PF12768.2 EEQ74703.1 - 0.0017 17.6 0.0 0.0036 16.5 0.0 1.5 1 0 0 1 1 1 1 Cortical protein marker for cell polarity PD40 PF07676.7 EEQ74703.1 - 0.049 13.3 0.2 0.32 10.7 0.1 2.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat BBP1_C PF15272.1 EEQ74704.1 - 0.21 11.1 2.4 0.33 10.4 1.6 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal HTH_Tnp_Tc5 PF03221.11 EEQ74705.1 - 5.2e-18 64.6 0.1 1.2e-17 63.4 0.1 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain ScpA_ScpB PF02616.9 EEQ74705.1 - 0.74 9.3 3.2 0.28 10.7 0.3 1.6 2 0 0 2 2 2 0 ScpA/B protein Glyco_hydro_43 PF04616.9 EEQ74706.1 - 8.5e-25 87.4 0.8 2.8e-24 85.7 0.6 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Lipase_3 PF01764.20 EEQ74708.1 - 1.1e-32 112.6 0.0 2.3e-32 111.5 0.0 1.6 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EEQ74708.1 - 0.0034 17.1 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ74708.1 - 0.021 14.6 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EEQ74708.1 - 0.036 13.6 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Cutinase PF01083.17 EEQ74708.1 - 0.065 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Cutinase Myf5 PF12232.3 EEQ74708.1 - 0.39 11.3 3.0 0.39 11.3 0.4 2.2 2 0 0 2 2 2 0 Myogenic determination factor 5 WW PF00397.21 EEQ74709.1 - 5.9e-09 35.6 0.6 1.4e-08 34.4 0.4 1.7 1 0 0 1 1 1 1 WW domain PhoD PF09423.5 EEQ74709.1 - 0.048 12.2 0.2 0.077 11.5 0.1 1.2 1 0 0 1 1 1 0 PhoD-like phosphatase Chlorosome_CsmC PF11098.3 EEQ74709.1 - 0.27 10.9 1.4 0.51 10.0 1.0 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C Fungal_trans_2 PF11951.3 EEQ74711.1 - 2.9e-26 91.9 0.5 4.4e-26 91.3 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ecm29 PF13001.2 EEQ74713.1 - 1.3e-161 538.5 0.0 6.4e-161 536.2 0.0 2.3 2 1 0 3 3 3 1 Proteasome stabiliser HEAT PF02985.17 EEQ74713.1 - 6e-08 32.1 3.4 0.41 10.8 0.0 8.4 10 0 0 10 10 10 2 HEAT repeat HEAT_2 PF13646.1 EEQ74713.1 - 0.007 16.6 8.6 0.21 11.9 0.0 6.6 7 2 1 8 8 8 2 HEAT repeats HEAT_EZ PF13513.1 EEQ74713.1 - 0.095 13.2 13.4 0.2 12.1 0.1 6.9 8 0 0 8 8 8 0 HEAT-like repeat SNF2_N PF00176.18 EEQ74714.1 - 5.1e-55 186.3 0.0 8.8e-55 185.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.20 EEQ74714.1 - 1.3e-08 34.3 8.4 3.4e-08 32.9 5.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ74714.1 - 8.2e-08 31.9 10.8 1.9e-07 30.7 7.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEQ74714.1 - 6.6e-07 28.9 7.6 1.7e-06 27.5 5.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ74714.1 - 7.2e-07 29.1 10.5 2e-06 27.7 7.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEQ74714.1 - 0.00011 22.1 5.7 0.00036 20.5 3.9 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger TPR_2 PF07719.12 EEQ74714.1 - 0.00056 19.6 0.7 0.002 17.9 0.5 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat Helicase_C PF00271.26 EEQ74714.1 - 0.0008 19.2 0.0 0.002 17.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EEQ74714.1 - 0.0015 18.2 8.8 0.0036 16.9 6.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain TPR_14 PF13428.1 EEQ74714.1 - 0.0056 17.2 1.1 0.033 14.8 0.8 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ74714.1 - 0.017 14.7 0.2 0.05 13.2 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C3HC4_4 PF15227.1 EEQ74714.1 - 0.023 14.5 7.8 0.051 13.4 5.4 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.6 EEQ74714.1 - 0.026 14.2 0.3 0.062 13.0 0.2 1.7 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.1 EEQ74714.1 - 0.058 12.9 4.1 0.14 11.6 2.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 EEQ74714.1 - 0.2 11.4 6.9 0.56 9.9 4.8 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Pkinase PF00069.20 EEQ74715.1 - 8.1e-37 126.7 0.0 1.4e-36 125.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ74715.1 - 2.5e-11 43.1 0.0 1.5e-10 40.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase COesterase PF00135.23 EEQ74716.1 - 1.4e-101 340.8 0.0 2.2e-101 340.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEQ74716.1 - 1.2e-05 24.9 0.0 2.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEQ74716.1 - 0.0049 16.1 0.0 0.0079 15.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Pribosyltran PF00156.22 EEQ74717.1 - 2e-15 56.6 0.0 3.3e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PMP22_Claudin PF00822.15 EEQ74717.1 - 0.14 11.8 0.1 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Fig1 PF12351.3 EEQ74718.1 - 7.5e-38 130.2 6.9 7.5e-38 130.2 4.8 2.7 2 1 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Ank_2 PF12796.2 EEQ74719.1 - 9.4e-29 99.6 2.6 6.2e-12 45.7 0.3 4.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ74719.1 - 6.7e-26 88.7 6.8 9.8e-06 25.1 0.1 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 EEQ74719.1 - 1.3e-22 77.5 4.0 1.8e-05 24.4 0.1 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 EEQ74719.1 - 3.1e-20 71.7 4.7 3.8e-07 30.1 0.1 4.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEQ74719.1 - 3e-19 68.9 2.0 2.6e-07 30.9 0.0 3.7 2 1 0 3 3 3 3 Ankyrin repeats (many copies) CN_hydrolase PF00795.17 EEQ74720.1 - 2.2e-24 85.8 0.0 3.2e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PMM PF03332.8 EEQ74721.1 - 3.9e-103 343.7 0.1 4.6e-103 343.5 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EEQ74721.1 - 0.00052 19.6 0.0 0.0012 18.5 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 EEQ74721.1 - 0.067 12.2 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF1640 PF07798.6 EEQ74722.1 - 7e-63 211.8 3.9 8.4e-63 211.6 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Syntaxin PF00804.20 EEQ74722.1 - 1.5 9.0 5.8 5 7.3 3.6 2.1 1 1 0 1 1 1 0 Syntaxin PNGaseA PF12222.3 EEQ74723.1 - 2e-160 534.3 0.7 2.6e-160 533.9 0.5 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Fungal_trans PF04082.13 EEQ74725.1 - 9.6e-25 86.9 1.1 1.9e-24 85.9 0.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ74725.1 - 4.5e-07 29.6 9.0 4.5e-07 29.6 6.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_D3 PF04580.8 EEQ74725.1 - 0.015 14.5 0.0 0.032 13.4 0.0 1.4 2 0 0 2 2 2 0 Chordopoxvirinae D3 protein MFS_1 PF07690.11 EEQ74726.1 - 2e-26 92.5 52.1 5.2e-26 91.1 34.9 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ74726.1 - 1.5e-09 36.6 30.2 2.2e-09 36.0 20.8 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DnaJ PF00226.26 EEQ74727.1 - 3.8e-15 55.3 0.3 1.8e-10 40.3 0.1 2.4 2 0 0 2 2 2 2 DnaJ domain Bacteriocin_IIc PF10439.4 EEQ74727.1 - 0.0074 16.3 3.3 0.011 15.7 2.3 1.3 1 0 0 1 1 1 1 Bacteriocin class II with double-glycine leader peptide Gly-zipper_OmpA PF13436.1 EEQ74727.1 - 0.041 13.5 5.3 0.087 12.4 3.7 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Orthopox_F8 PF05886.6 EEQ74727.1 - 0.045 13.5 1.3 0.089 12.6 0.9 1.5 1 0 0 1 1 1 0 Orthopoxvirus F8 protein Rick_17kDa_Anti PF05433.10 EEQ74727.1 - 2.2 8.0 17.4 5.9 6.6 12.0 1.7 1 1 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 EEQ74727.1 - 5 6.8 15.2 9.1 6.0 10.5 1.4 1 0 0 1 1 1 0 Glycine zipper DnaJ PF00226.26 EEQ74731.1 - 4.9e-11 42.1 0.1 1.1e-10 41.0 0.1 1.6 1 1 0 1 1 1 1 DnaJ domain PRA1 PF03208.14 EEQ74732.1 - 6.9e-40 135.9 1.2 7.9e-40 135.7 0.9 1.1 1 0 0 1 1 1 1 PRA1 family protein Dynamin_N PF00350.18 EEQ74734.1 - 1.9e-06 27.8 0.0 3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EEQ74734.1 - 0.00043 19.1 0.0 0.00076 18.3 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region FeoB_N PF02421.13 EEQ74734.1 - 0.045 13.0 0.3 0.095 11.9 0.2 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EEQ74734.1 - 0.096 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase APH PF01636.18 EEQ74735.1 - 3.9e-18 66.0 0.0 5e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ74735.1 - 3.4e-05 23.5 0.0 7.7e-05 22.3 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Frag1 PF10277.4 EEQ74739.1 - 1.1e-22 80.5 5.6 2.5e-13 49.9 3.0 2.1 2 0 0 2 2 2 2 Frag1/DRAM/Sfk1 family Y_phosphatase3 PF13350.1 EEQ74740.1 - 3.5e-12 46.8 0.0 7.3e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EEQ74740.1 - 4.7e-06 26.6 0.1 1.1e-05 25.4 0.1 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EEQ74740.1 - 6e-06 25.7 0.0 9.4e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EEQ74740.1 - 0.093 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF3812 PF12757.2 EEQ74742.1 - 1e-26 93.3 9.2 1e-26 93.3 6.4 3.8 3 2 1 4 4 4 1 Protein of unknown function (DUF3812) Acetyltransf_3 PF13302.1 EEQ74743.1 - 4.2e-15 56.1 0.0 5.5e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EEQ74743.1 - 1.4e-08 34.8 0.0 2.4e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEQ74743.1 - 0.0018 18.2 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Peptidase_C69 PF03577.10 EEQ74744.1 - 8.3e-08 31.5 0.0 1.8e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C69 adh_short PF00106.20 EEQ74745.1 - 2.9e-08 33.8 0.4 0.00025 21.0 0.2 2.3 1 1 1 2 2 2 2 short chain dehydrogenase NAD_binding_10 PF13460.1 EEQ74745.1 - 1.4e-05 25.1 0.0 2.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEQ74745.1 - 3.7e-05 23.2 0.1 7.2e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EEQ74745.1 - 0.008 15.8 0.3 0.02 14.5 0.2 1.7 1 1 0 1 1 1 1 KR domain NAD_Gly3P_dh_N PF01210.18 EEQ74745.1 - 0.04 13.6 0.1 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus adh_short_C2 PF13561.1 EEQ74745.1 - 0.097 12.4 0.4 2 8.0 0.1 2.3 2 1 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Aldo_ket_red PF00248.16 EEQ74746.1 - 8.2e-17 60.9 0.0 1.1e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.20 EEQ74748.1 - 3e-66 223.2 0.0 3e-66 223.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ74748.1 - 5e-40 137.2 0.0 7.2e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ74748.1 - 1.9e-10 40.1 0.0 2.9e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EEQ74748.1 - 1.3e-05 25.0 4.0 0.084 12.5 0.4 3.2 2 1 1 3 3 3 3 Phosphotransferase enzyme family Kdo PF06293.9 EEQ74748.1 - 0.084 11.9 1.3 0.29 10.1 0.0 2.3 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family HeLo PF14479.1 EEQ74749.1 - 8.5e-44 149.8 0.0 1.3e-42 145.9 0.0 2.3 2 0 0 2 2 2 1 Prion-inhibition and propagation AAA PF00004.24 EEQ74749.1 - 2e-17 63.6 0.0 4.7e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEQ74749.1 - 0.00012 22.0 0.3 0.00039 20.4 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEQ74749.1 - 0.0004 20.5 0.1 0.0036 17.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEQ74749.1 - 0.00043 21.0 0.0 0.0018 19.0 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEQ74749.1 - 0.00046 19.9 0.0 0.0098 15.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EEQ74749.1 - 0.0016 18.3 0.0 0.0052 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEQ74749.1 - 0.0017 18.6 0.0 0.0069 16.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ74749.1 - 0.0024 17.5 0.0 0.0082 15.8 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EEQ74749.1 - 0.003 16.9 0.0 0.0092 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EEQ74749.1 - 0.0058 16.6 0.6 0.032 14.1 0.4 2.4 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 EEQ74749.1 - 0.011 15.3 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TIP49 PF06068.8 EEQ74749.1 - 0.011 14.4 0.0 0.021 13.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Zeta_toxin PF06414.7 EEQ74749.1 - 0.016 14.3 0.0 0.036 13.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.1 EEQ74749.1 - 0.14 11.6 0.0 0.44 10.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EEQ74749.1 - 0.19 11.2 0.2 0.45 10.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain Prenyltrans PF00432.16 EEQ74750.1 - 4.6e-31 106.0 8.4 1.8e-06 27.4 0.0 6.5 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EEQ74750.1 - 1.9e-23 83.0 0.0 6.7e-17 61.9 0.0 3.5 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EEQ74750.1 - 2.1e-06 27.7 0.0 0.0076 16.2 0.0 3.4 2 1 0 3 3 3 2 Prenyltransferase-like Ilm1 PF10311.4 EEQ74751.1 - 2.2e-23 82.5 0.7 3.2e-23 82.0 0.5 1.2 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 CFEM PF05730.6 EEQ74752.1 - 6.3e-11 41.9 15.6 1.1e-10 41.2 10.8 1.4 1 0 0 1 1 1 1 CFEM domain MFS_1 PF07690.11 EEQ74753.1 - 1.1e-32 113.1 13.1 1.1e-32 113.1 9.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.2 EEQ74754.1 - 4.5e-74 244.8 3.9 7.9e-18 64.5 0.0 5.3 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ74754.1 - 1.8e-51 169.4 3.1 4.7e-06 26.1 0.0 9.6 8 1 1 9 9 9 9 Ankyrin repeat Ank_3 PF13606.1 EEQ74754.1 - 4.1e-40 131.7 0.1 2.1e-05 24.3 0.0 10.1 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.1 EEQ74754.1 - 8.3e-39 130.7 3.5 7.7e-08 32.3 0.0 6.9 3 3 3 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEQ74754.1 - 1.1e-35 121.4 0.7 1.3e-10 41.5 0.0 6.4 5 1 0 6 6 6 5 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 EEQ74754.1 - 2.8e-11 42.8 0.0 5.6e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily Shigella_OspC PF06128.6 EEQ74754.1 - 0.0058 16.1 0.0 1.4 8.3 0.0 3.3 2 1 1 3 3 3 1 Shigella flexneri OspC protein MFS_1 PF07690.11 EEQ74755.1 - 8.9e-33 113.4 36.0 8.9e-33 113.4 24.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Syndecan PF01034.15 EEQ74755.1 - 0.33 10.6 1.6 31 4.2 0.1 3.0 2 0 0 2 2 2 0 Syndecan domain DUF3354 PF11834.3 EEQ74756.1 - 0.077 12.6 0.0 0.58 9.8 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3354) MFS_1 PF07690.11 EEQ74757.1 - 4e-10 38.9 43.1 4e-10 38.9 29.9 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EEQ74757.1 - 9.6e-09 34.9 4.4 9.6e-09 34.9 3.1 2.9 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 CBM_5_12 PF02839.9 EEQ74759.1 - 3.7e-06 26.4 3.2 3.7e-06 26.4 2.2 2.4 2 0 0 2 2 2 1 Carbohydrate binding domain PT-TG PF14449.1 EEQ74760.1 - 0.00011 21.9 0.2 0.0004 20.1 0.0 2.1 2 0 0 2 2 2 1 Pre-toxin TG Ribosomal_L7Ae PF01248.21 EEQ74761.1 - 7.3e-26 89.5 0.0 8.6e-26 89.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EEQ74761.1 - 3.7e-05 23.6 0.1 4.4e-05 23.3 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EEQ74761.1 - 0.0072 16.0 0.0 0.0097 15.6 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain E1-E2_ATPase PF00122.15 EEQ74762.1 - 5e-65 218.7 10.3 7.4e-65 218.2 4.8 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEQ74762.1 - 6.2e-44 149.6 8.4 6.2e-44 149.6 5.8 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEQ74762.1 - 3.9e-33 115.6 0.0 4.2e-32 112.2 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ74762.1 - 1.9e-20 72.5 0.0 4.3e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EEQ74762.1 - 6.7e-19 67.1 0.0 1.8e-18 65.7 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EEQ74762.1 - 1.7e-16 60.9 0.0 5.4e-16 59.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEQ74762.1 - 4.7e-08 32.9 1.1 1e-05 25.2 0.7 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EEQ74762.1 - 0.011 15.9 0.0 0.033 14.4 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Ank_2 PF12796.2 EEQ74763.1 - 3.4e-28 97.7 5.2 2.3e-12 47.0 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEQ74763.1 - 5.2e-14 52.2 1.0 3.5e-07 30.5 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 EEQ74763.1 - 7.2e-14 50.8 11.1 3.6e-05 23.3 0.3 5.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 EEQ74763.1 - 1.9e-11 43.0 2.4 0.02 15.0 0.1 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 EEQ74763.1 - 7.6e-10 38.7 5.9 0.62 10.3 0.0 5.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Pkinase PF00069.20 EEQ74763.1 - 0.14 11.3 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain 14-3-3 PF00244.15 EEQ74764.1 - 9.2e-114 378.3 0.7 1.1e-113 378.1 0.5 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 EEQ74764.1 - 0.024 14.5 0.2 9.7 6.2 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF837 PF05769.6 EEQ74764.1 - 0.12 11.9 0.5 11 5.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF837) eIF3_subunit PF08597.5 EEQ74767.1 - 8.4e-68 228.5 27.9 9.5e-68 228.3 19.3 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit TFIIF_alpha PF05793.7 EEQ74767.1 - 0.0013 17.2 18.4 0.0013 17.2 12.7 2.0 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BTV_NS2 PF04514.7 EEQ74767.1 - 0.0047 15.8 13.2 0.007 15.2 9.2 1.3 1 0 0 1 1 1 1 Bluetongue virus non-structural protein NS2 FLO_LFY PF01698.11 EEQ74767.1 - 0.38 9.5 15.8 0.43 9.3 8.7 2.0 2 0 0 2 2 2 0 Floricaula / Leafy protein Nucleo_P87 PF07267.6 EEQ74767.1 - 2.8 6.5 17.8 1.9 7.1 11.3 1.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Senescence_reg PF04520.8 EEQ74767.1 - 2.8 8.4 15.2 6.5 7.2 8.8 2.3 2 0 0 2 2 2 0 Senescence regulator Plasmodium_Vir PF05795.6 EEQ74767.1 - 4.1 6.5 7.8 1.8 7.7 2.8 1.8 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF2146 PF10220.4 EEQ74767.1 - 5.2 4.9 6.6 6.8 4.5 4.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Rgp1 PF08737.5 EEQ74767.1 - 6.8 5.6 6.0 40 3.1 2.6 2.0 2 0 0 2 2 2 0 Rgp1 GAGA_bind PF06217.7 EEQ74767.1 - 9.7 6.0 11.3 2 8.3 4.3 1.9 2 0 0 2 2 2 0 GAGA binding protein-like family HNH_2 PF13391.1 EEQ74768.1 - 9.3e-08 31.7 0.0 1.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease Peptidase_C21 PF05381.7 EEQ74768.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Tymovirus endopeptidase Enolase_C PF00113.17 EEQ74769.1 - 2e-154 512.8 0.1 2.5e-154 512.5 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EEQ74769.1 - 9.7e-57 190.5 0.7 1.9e-56 189.6 0.1 1.7 2 0 0 2 2 2 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EEQ74769.1 - 0.0085 16.0 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EEQ74769.1 - 0.036 14.5 0.0 0.081 13.4 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MAAL_C PF07476.6 EEQ74769.1 - 0.12 11.2 0.7 0.84 8.5 0.2 2.3 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus AAA PF00004.24 EEQ74770.1 - 5.4e-43 146.3 0.0 8.8e-43 145.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEQ74770.1 - 9.2e-08 32.2 0.0 2.5e-06 27.5 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EEQ74770.1 - 1.6e-06 27.9 0.1 3.7e-05 23.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EEQ74770.1 - 2.5e-06 27.5 0.0 7.7e-06 25.9 0.0 1.8 3 0 0 3 3 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EEQ74770.1 - 2.9e-06 27.4 0.0 0.001 19.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EEQ74770.1 - 7.3e-06 25.1 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EEQ74770.1 - 0.00021 20.3 0.0 0.00058 18.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EEQ74770.1 - 0.00034 20.2 0.0 0.00076 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EEQ74770.1 - 0.00071 20.3 0.5 0.0028 18.4 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EEQ74770.1 - 0.0012 18.7 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEQ74770.1 - 0.0017 18.2 0.0 0.0063 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EEQ74770.1 - 0.0018 17.0 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 EEQ74770.1 - 0.0027 17.1 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 EEQ74770.1 - 0.0028 17.9 0.0 0.0081 16.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EEQ74770.1 - 0.0031 16.6 0.0 0.0062 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EEQ74770.1 - 0.005 16.9 0.0 0.0097 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 EEQ74770.1 - 0.0058 15.7 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EEQ74770.1 - 0.0075 15.7 0.0 0.027 13.9 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 EEQ74770.1 - 0.0087 15.4 0.1 0.047 13.0 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 EEQ74770.1 - 0.0094 15.5 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EEQ74770.1 - 0.015 14.8 0.1 0.26 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EEQ74770.1 - 0.019 14.5 0.1 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EEQ74770.1 - 0.022 14.6 0.0 0.062 13.1 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.1 EEQ74770.1 - 0.023 14.7 0.0 0.065 13.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 EEQ74770.1 - 0.023 14.3 0.1 0.13 11.8 0.0 2.3 2 1 0 2 2 2 0 Archaeal ATPase AAA_28 PF13521.1 EEQ74770.1 - 0.024 14.5 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EEQ74770.1 - 0.026 13.6 0.0 0.11 11.5 0.0 2.1 2 0 0 2 2 2 0 KaiC PhoH PF02562.11 EEQ74770.1 - 0.032 13.4 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein DUF4200 PF13863.1 EEQ74770.1 - 0.036 14.0 0.4 0.093 12.6 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) AAA_23 PF13476.1 EEQ74770.1 - 0.038 14.3 1.5 3.5 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EEQ74770.1 - 0.041 13.5 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 EEQ74770.1 - 0.052 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EEQ74770.1 - 0.084 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EEQ74770.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Glyco_hydro_47 PF01532.15 EEQ74771.1 - 4e-163 543.2 0.0 4.9e-163 542.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4038 PF13204.1 EEQ74771.1 - 0.0021 17.4 0.0 0.0047 16.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Peptidase_M20 PF01546.23 EEQ74772.1 - 2.4e-18 66.3 0.1 3.3e-18 65.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EEQ74772.1 - 6e-18 64.6 0.0 1.4e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.9 EEQ74772.1 - 0.04 12.7 0.0 0.82 8.3 0.0 2.1 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase HATPase_c PF02518.21 EEQ74773.1 - 4.9e-19 68.0 0.0 8.9e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EEQ74773.1 - 8.2e-15 54.7 0.4 6.6e-08 32.5 0.1 3.4 2 1 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 EEQ74773.1 - 5.9e-06 26.1 1.2 1.1e-05 25.3 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 EEQ74773.1 - 0.032 13.8 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MSA-2c PF12238.3 EEQ74773.1 - 3.2 7.3 7.7 44 3.6 6.0 2.3 2 0 0 2 2 2 0 Merozoite surface antigen 2c Ribosomal_L36e PF01158.13 EEQ74774.1 - 2e-40 136.7 7.4 2.2e-40 136.5 5.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 EEQ74774.1 - 0.0028 16.7 0.1 0.0032 16.6 0.1 1.0 1 0 0 1 1 1 1 LemA family MRP-L28 PF09812.4 EEQ74774.1 - 0.062 13.1 1.5 0.075 12.8 1.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 DUF1932 PF09130.6 EEQ74774.1 - 0.1 12.3 0.5 1 9.1 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1932) TUG-UBL1 PF11470.3 EEQ74775.1 - 2.1e-26 91.6 0.1 5e-26 90.4 0.0 1.7 1 0 0 1 1 1 1 GLUT4 regulating protein TUG UBX PF00789.15 EEQ74775.1 - 1.1e-05 25.4 0.0 5.5e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 UBX domain RBD PF02196.10 EEQ74775.1 - 0.011 15.4 0.1 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Raf-like Ras-binding domain Rad60-SLD PF11976.3 EEQ74775.1 - 0.094 12.4 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF605 PF04652.11 EEQ74775.1 - 1.9 7.7 18.8 2.8 7.2 13.1 1.1 1 0 0 1 1 1 0 Vta1 like MSA-2c PF12238.3 EEQ74775.1 - 9.8 5.7 7.1 21 4.7 5.0 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c Hemerythrin PF01814.18 EEQ74776.1 - 1.1e-09 38.5 0.1 1.5e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Proteasome PF00227.21 EEQ74777.1 - 3.4e-37 127.5 0.0 3.9e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit NatB_MDM20 PF09797.4 EEQ74778.1 - 1.6e-100 336.3 0.4 3.1e-100 335.4 0.3 1.5 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.1 EEQ74778.1 - 0.00017 21.8 7.8 0.19 12.0 0.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ74778.1 - 0.15 12.7 8.7 3.8 8.3 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA PF00004.24 EEQ74780.1 - 3.6e-18 66.0 0.0 9e-18 64.7 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEQ74780.1 - 0.00011 22.3 0.2 0.00055 20.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEQ74780.1 - 0.00024 21.1 0.0 0.00076 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EEQ74780.1 - 0.003 17.4 0.0 0.053 13.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEQ74780.1 - 0.0033 18.2 1.3 0.017 15.9 0.5 2.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ74780.1 - 0.0076 15.9 1.1 0.03 14.0 0.4 2.1 2 0 0 2 2 2 1 Part of AAA domain CPT PF07931.7 EEQ74780.1 - 0.0089 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_5 PF07728.9 EEQ74780.1 - 0.013 15.1 0.0 0.043 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EEQ74780.1 - 0.02 13.9 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EEQ74780.1 - 0.045 14.0 2.1 0.11 12.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EEQ74780.1 - 0.077 12.6 0.1 0.31 10.6 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Zot PF05707.7 EEQ74780.1 - 0.082 12.3 0.5 1.5 8.2 0.0 2.5 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) 2OG-FeII_Oxy_3 PF13640.1 EEQ74783.1 - 0.0078 16.7 0.0 0.014 15.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DZR PF12773.2 EEQ74784.1 - 0.057 13.2 7.4 2.3 8.0 0.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-Apc11 PF12861.2 EEQ74784.1 - 0.59 10.0 3.4 1.1 9.2 0.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger UPF0547 PF10571.4 EEQ74784.1 - 1.1 9.0 14.2 0.27 10.9 0.5 3.1 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 FYVE_2 PF02318.11 EEQ74784.1 - 1.7 8.5 5.2 45 3.9 0.1 3.1 3 0 0 3 3 3 0 FYVE-type zinc finger DTHCT PF08070.6 EEQ74784.1 - 3.2 8.4 7.9 2.4 8.8 2.9 2.7 1 1 1 2 2 2 0 DTHCT (NUC029) region TFIIF_alpha PF05793.7 EEQ74784.1 - 3.5 5.8 21.3 6.6 4.9 14.8 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PPV_E1_N PF00524.13 EEQ74784.1 - 7.7 6.7 13.8 0.74 10.0 0.7 2.6 2 0 0 2 2 2 0 E1 Protein, N terminal domain WD40 PF00400.27 EEQ74785.1 - 5.4e-27 92.6 16.6 2.5e-07 30.3 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EEQ74785.1 - 0.012 14.3 1.1 0.49 9.0 0.0 2.8 2 1 0 3 3 3 0 Nup133 N terminal like DUF648 PF04890.8 EEQ74785.1 - 0.18 10.9 0.1 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF648) Proteasome PF00227.21 EEQ74786.1 - 1.2e-32 112.7 0.0 1.4e-32 112.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit UCH PF00443.24 EEQ74787.1 - 1.5e-22 80.0 0.0 6.3e-21 74.6 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EEQ74787.1 - 3e-11 43.2 0.2 3e-11 43.2 0.1 1.8 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EEQ74787.1 - 0.0013 18.2 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 EEQ74789.1 - 2.1e-74 242.9 28.4 1.5e-09 37.3 0.3 11.8 11 1 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 EEQ74789.1 - 8.3e-49 164.8 0.1 1.3e-48 164.1 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EEQ74789.1 - 1.6e-10 39.7 13.5 8e-05 20.9 3.1 5.2 3 2 0 3 3 3 3 Nucleoporin Nup120/160 COPR5 PF15340.1 EEQ74789.1 - 0.078 13.3 0.0 1.7 9.0 0.0 2.9 3 0 0 3 3 3 0 Cooperator of PRMT5 family DUF3312 PF11768.3 EEQ74789.1 - 0.28 9.3 0.0 1.8 6.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) G-patch_2 PF12656.2 EEQ74790.1 - 3.4e-28 97.2 0.1 1.3e-27 95.3 0.0 2.1 1 0 0 1 1 1 1 DExH-box splicing factor binding site G-patch PF01585.18 EEQ74790.1 - 0.00021 21.0 0.5 0.00064 19.4 0.4 1.9 1 0 0 1 1 1 1 G-patch domain HSA PF07529.8 EEQ74791.1 - 8.6e-25 86.3 0.3 8.6e-25 86.3 0.2 3.9 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.1 EEQ74791.1 - 3.8e-13 49.3 0.1 6.9e-12 45.2 0.1 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain WD40 PF00400.27 EEQ74792.1 - 9.5e-09 34.8 0.0 0.66 9.9 0.0 5.0 4 0 0 4 4 4 4 WD domain, G-beta repeat GTP_EFTU PF00009.22 EEQ74793.1 - 8.1e-39 133.0 0.0 1.3e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EEQ74793.1 - 1.2e-36 124.6 0.1 2.3e-36 123.7 0.1 1.5 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EEQ74793.1 - 1.1e-11 44.7 0.3 2.4e-11 43.5 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEQ74793.1 - 0.0066 16.3 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EEQ74793.1 - 0.12 12.2 0.2 0.35 10.6 0.1 1.9 1 1 0 1 1 1 0 Dynamin family Ribosomal_L34 PF00468.12 EEQ74794.1 - 3.8e-18 64.8 10.0 8.2e-18 63.8 6.9 1.6 1 0 0 1 1 1 1 Ribosomal protein L34 RNA_polI_A14 PF08203.6 EEQ74795.1 - 0.018 15.2 0.0 0.035 14.3 0.0 1.5 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Peptidase_M48 PF01435.13 EEQ74796.1 - 3.5e-52 177.2 0.0 5.4e-52 176.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 EEQ74796.1 - 0.0051 15.8 0.6 0.015 14.2 0.1 1.9 2 0 0 2 2 2 1 BlaR1 peptidase M56 DUF4538 PF15061.1 EEQ74796.1 - 0.017 14.3 1.1 0.04 13.2 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) DUF2201_N PF13203.1 EEQ74796.1 - 0.2 10.8 0.1 0.42 9.7 0.1 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF955 PF06114.8 EEQ74796.1 - 0.31 10.7 1.6 1.2 8.8 1.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF955) Peptidase_M16_C PF05193.16 EEQ74797.1 - 1.1e-17 64.2 0.0 1.8e-13 50.5 0.0 3.0 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EEQ74797.1 - 2.8e-05 23.9 0.2 0.0001 22.1 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) HD_assoc PF13286.1 EEQ74797.1 - 0.08 13.2 0.0 0.6 10.4 0.0 2.4 2 0 0 2 2 2 0 Phosphohydrolase-associated domain Zw10 PF06248.8 EEQ74798.1 - 1.3e-16 59.9 0.1 2.5e-14 52.3 0.0 2.2 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 EEQ74798.1 - 3e-06 26.6 0.2 1.4e-05 24.4 0.0 2.2 3 0 0 3 3 3 1 Retrograde transport protein Dsl1 C terminal Syntaxin-6_N PF09177.6 EEQ74798.1 - 5.1e-05 23.5 3.6 0.026 14.8 0.0 3.1 2 1 0 2 2 2 2 Syntaxin 6, N-terminal Tropomyosin_1 PF12718.2 EEQ74798.1 - 4.8 7.0 10.6 0.42 10.4 3.0 2.3 2 1 0 2 2 2 0 Tropomyosin like Fib_alpha PF08702.5 EEQ74798.1 - 5.8 7.0 5.7 3.7 7.6 1.3 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family WD40 PF00400.27 EEQ74799.1 - 1.9e-30 103.6 18.1 4e-08 32.8 0.4 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat NLE PF08154.7 EEQ74799.1 - 5.5e-20 71.1 0.1 1.5e-19 69.7 0.0 1.8 2 0 0 2 2 2 1 NLE (NUC135) domain Ribosomal_S13 PF00416.17 EEQ74800.1 - 2.7e-14 53.4 0.7 3.1e-14 53.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Pro_isomerase PF00160.16 EEQ74801.1 - 7.7e-47 159.3 0.7 9.2e-47 159.1 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Fungal_trans_2 PF11951.3 EEQ74802.1 - 0.00034 19.3 0.4 0.025 13.1 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain NmrA PF05368.8 EEQ74803.1 - 2.4e-21 76.0 0.0 3.3e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEQ74803.1 - 5.8e-11 42.7 0.1 8.7e-11 42.1 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 EEQ74803.1 - 0.0054 16.6 0.4 0.011 15.6 0.3 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus THF_DHG_CYH_C PF02882.14 EEQ74803.1 - 0.013 14.5 1.2 0.048 12.7 0.8 1.9 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2376 PF09550.5 EEQ74803.1 - 0.055 13.6 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Conserved hypothetical phage protein (DUF2376) DEAD PF00270.24 EEQ74804.1 - 5e-47 159.5 0.0 6.1e-46 155.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ74804.1 - 2.6e-27 94.4 0.0 6.5e-27 93.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EEQ74804.1 - 0.0085 14.5 0.0 0.071 11.5 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1253) ResIII PF04851.10 EEQ74804.1 - 0.034 13.9 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit INSIG PF07281.7 EEQ74806.1 - 1.7e-61 206.9 1.1 2.5e-61 206.4 0.8 1.2 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) Dicty_REP PF05086.7 EEQ74806.1 - 0.41 8.3 2.0 0.54 7.9 1.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AICARFT_IMPCHas PF01808.13 EEQ74807.1 - 6e-101 337.6 0.1 5.4e-79 265.5 0.0 2.2 1 1 1 2 2 2 2 AICARFT/IMPCHase bienzyme MGS PF02142.17 EEQ74807.1 - 7.8e-25 86.6 0.0 1.3e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain Clathrin PF00637.15 EEQ74808.1 - 2.2e-202 662.7 43.7 3.1e-36 124.1 1.1 7.3 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EEQ74808.1 - 2.1e-25 88.3 0.0 9e-25 86.3 0.0 2.2 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.5 EEQ74808.1 - 7.1e-10 37.7 0.0 1.7e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Clathrin_propel PF01394.15 EEQ74808.1 - 1.3e-08 34.5 0.5 5 7.6 0.0 6.3 7 0 0 7 7 7 3 Clathrin propeller repeat Vps39_1 PF10366.4 EEQ74808.1 - 0.00035 20.5 1.7 1.9 8.5 0.0 4.8 3 1 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 TPR_7 PF13176.1 EEQ74808.1 - 0.0012 18.4 3.4 60 3.8 0.0 6.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ74808.1 - 0.0063 16.4 0.4 3.6 7.5 0.0 4.7 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2191 PF09957.4 EEQ74808.1 - 0.021 14.6 0.1 0.084 12.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2191) TPR_14 PF13428.1 EEQ74808.1 - 0.027 15.0 13.0 11 6.9 0.1 7.2 9 0 0 9 9 5 0 Tetratricopeptide repeat Ank_3 PF13606.1 EEQ74808.1 - 0.093 13.0 0.0 1.1 9.6 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat TPR_19 PF14559.1 EEQ74808.1 - 0.21 11.9 6.3 37 4.7 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DIM1 PF02966.11 EEQ74809.1 - 2.6e-70 234.0 0.2 3e-70 233.9 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 EEQ74809.1 - 0.0025 17.8 0.4 0.0044 17.1 0.3 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.15 EEQ74809.1 - 0.0061 16.2 0.0 0.0078 15.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EEQ74809.1 - 0.066 13.2 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like CPSase_L_D2 PF02786.12 EEQ74810.1 - 9.3e-81 270.1 0.1 1.4e-80 269.5 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EEQ74810.1 - 5.5e-50 169.5 0.0 1.1e-49 168.5 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EEQ74810.1 - 5.8e-36 122.9 0.0 1.2e-35 121.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EEQ74810.1 - 6.5e-29 100.0 0.0 1.5e-28 98.8 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EEQ74810.1 - 7.5e-25 87.9 0.0 1.4e-24 87.1 0.0 1.5 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 EEQ74810.1 - 2.7e-18 66.3 0.3 9e-18 64.6 0.1 1.9 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EEQ74810.1 - 9.4e-18 63.6 0.9 6.9e-17 60.8 0.3 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EEQ74810.1 - 3.9e-15 55.4 0.0 1.7e-14 53.3 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EEQ74810.1 - 2.8e-10 39.9 0.0 5.2e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EEQ74810.1 - 1.1e-07 31.3 0.0 2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EEQ74810.1 - 3.4e-07 29.8 0.2 0.0096 15.5 0.0 3.6 2 1 1 3 3 3 2 Biotin-lipoyl like RimK PF08443.6 EEQ74810.1 - 8e-06 25.4 0.1 2.2e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EEQ74810.1 - 3.9e-05 23.5 0.1 0.00012 21.9 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain HlyD_2 PF12700.2 EEQ74810.1 - 0.033 13.3 0.0 2.8 6.9 0.0 2.2 1 1 1 2 2 2 0 HlyD family secretion protein GARS_A PF01071.14 EEQ74810.1 - 0.042 13.4 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CENP-B_dimeris PF09026.5 EEQ74811.1 - 0.026 14.7 4.2 0.033 14.4 2.9 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 EEQ74811.1 - 0.08 13.2 4.7 0.12 12.6 3.2 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 EEQ74811.1 - 0.15 11.5 6.3 0.19 11.2 4.4 1.1 1 0 0 1 1 1 0 Nucleoplasmin DUF688 PF05097.7 EEQ74811.1 - 0.17 10.8 1.9 0.19 10.6 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF688) BAF1_ABF1 PF04684.8 EEQ74811.1 - 0.2 10.4 3.0 0.24 10.1 2.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor NOA36 PF06524.7 EEQ74811.1 - 1.5 7.9 5.8 1.8 7.7 4.0 1.1 1 0 0 1 1 1 0 NOA36 protein TFIIA PF03153.8 EEQ74811.1 - 2.4 7.9 10.8 2.8 7.7 7.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Beta-lactamase PF00144.19 EEQ74812.1 - 1.9e-63 214.4 0.2 2.4e-63 214.1 0.1 1.0 1 0 0 1 1 1 1 Beta-lactamase Trypan_PARP PF05887.6 EEQ74813.1 - 1.1e-07 31.7 33.0 2e-07 30.9 22.9 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) zf-RING_2 PF13639.1 EEQ74813.1 - 1.5e-05 24.7 11.6 0.00051 19.8 8.0 2.7 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EEQ74813.1 - 0.00047 20.2 5.3 0.0013 18.7 3.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 EEQ74813.1 - 0.009 15.9 11.1 0.087 12.8 7.7 2.5 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_2 PF13923.1 EEQ74813.1 - 0.17 11.9 11.6 2.3 8.3 3.6 3.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Neisseria_TspB PF05616.8 EEQ74813.1 - 4.7 5.4 17.9 7.8 4.7 12.4 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein zf-C3HC4 PF00097.20 EEQ74813.1 - 7.4 6.3 14.8 1 9.0 5.1 3.1 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L5_C PF00673.16 EEQ74817.1 - 3.4e-22 77.9 0.0 4.8e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EEQ74817.1 - 2.7e-21 75.0 0.1 7.1e-21 73.7 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.17 EEQ74818.1 - 3.3e-18 64.9 0.0 4e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain MPC PF03650.8 EEQ74819.1 - 3.3e-34 117.4 0.1 4e-34 117.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Aa_trans PF01490.13 EEQ74820.1 - 2e-84 283.4 32.3 2.4e-84 283.2 22.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease PF00324.16 EEQ74821.1 - 4.3e-55 186.9 37.0 5.5e-55 186.5 25.7 1.1 1 0 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.19 EEQ74822.1 - 2.9e-108 362.3 11.8 3.7e-108 362.0 8.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ74822.1 - 5.9e-18 64.7 23.6 1.3e-14 53.7 1.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EEQ74822.1 - 7.2e-05 21.0 1.3 0.00015 19.9 0.8 1.7 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF2306 PF10067.4 EEQ74824.1 - 1.2e-09 38.2 8.7 1.2e-09 38.2 6.1 2.1 2 1 0 2 2 2 1 Predicted membrane protein (DUF2306) DUF3165 PF11364.3 EEQ74824.1 - 3.9 7.6 8.3 0.64 10.1 1.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3165) Zn_clus PF00172.13 EEQ74825.1 - 3.1e-05 23.8 9.6 5.5e-05 22.9 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GHMP_kinases_N PF00288.21 EEQ74827.1 - 4.3e-19 68.3 0.1 1e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EEQ74827.1 - 1.4e-07 31.6 0.0 3.9e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 EEQ74827.1 - 0.0047 16.1 0.0 0.012 14.8 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature PPTA PF01239.17 EEQ74828.1 - 4.5e-38 127.0 17.6 5.4e-08 31.8 1.4 5.7 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat PALP PF00291.20 EEQ74829.1 - 1.1e-46 159.4 0.6 4.4e-46 157.5 0.4 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme tRNA-synt_1g PF09334.6 EEQ74830.1 - 1.3e-116 389.5 0.0 2.2e-116 388.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EEQ74830.1 - 5.3e-21 74.2 0.2 1.9e-10 39.4 0.0 2.8 2 2 2 4 4 4 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EEQ74830.1 - 6.1e-10 38.7 0.0 0.00075 18.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 EEQ74830.1 - 0.00026 20.7 0.0 0.00052 19.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA NTF2 PF02136.15 EEQ74831.1 - 0.00015 22.1 0.4 0.00064 20.0 0.3 1.9 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 EEQ74831.1 - 0.0005 19.8 0.0 0.0065 16.2 0.0 2.1 2 0 0 2 2 2 1 Nuclear pore RNA shuttling protein Mtr2 Ribosomal_L38e PF01781.13 EEQ74832.1 - 7.2e-32 108.9 2.9 8.2e-32 108.7 2.0 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family CLTH PF10607.4 EEQ74832.1 - 0.015 14.9 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Acetyltransf_3 PF13302.1 EEQ74833.1 - 1.8e-14 54.1 0.0 1.2e-09 38.4 0.0 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ74833.1 - 0.0011 18.6 0.1 0.047 13.4 0.0 2.3 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.19 EEQ74833.1 - 0.0077 16.2 0.1 1.2 9.1 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EEQ74833.1 - 0.032 14.0 0.0 3.3 7.5 0.0 2.8 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Pkinase PF00069.20 EEQ74834.1 - 3.7e-07 29.5 0.2 1e-06 28.1 0.1 1.8 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EEQ74834.1 - 0.0003 19.9 0.1 0.00067 18.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ74834.1 - 0.0084 15.8 0.1 0.0084 15.8 0.1 3.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family OmpH PF03938.9 EEQ74834.1 - 2.9 7.7 8.4 0.39 10.6 2.7 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DNA_pol_E_B PF04042.11 EEQ74835.1 - 6.4e-49 166.0 0.0 9.3e-49 165.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B PLDc_2 PF13091.1 EEQ74837.1 - 1.4e-21 76.5 0.0 6.9e-14 51.6 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EEQ74837.1 - 0.00064 19.4 1.6 0.047 13.5 0.0 3.3 3 0 0 3 3 3 1 Phospholipase D Active site motif DUF3518 PF12031.3 EEQ74837.1 - 0.011 14.5 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3518) Regulator_TrmB PF11495.3 EEQ74837.1 - 0.032 13.2 0.1 0.34 9.8 0.0 2.2 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB NMO PF03060.10 EEQ74838.1 - 3.1e-72 243.4 3.4 3.6e-72 243.2 2.3 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EEQ74838.1 - 1.2e-05 24.4 0.0 0.00037 19.4 0.0 2.4 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EEQ74838.1 - 0.00037 19.4 1.6 0.00054 18.9 1.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Taxilin PF09728.4 EEQ74839.1 - 2.7e-97 325.5 40.8 2.7e-97 325.5 28.3 1.4 2 0 0 2 2 2 1 Myosin-like coiled-coil protein DUF3584 PF12128.3 EEQ74839.1 - 5.9e-05 20.6 37.4 0.00013 19.5 25.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_13 PF13166.1 EEQ74839.1 - 0.0002 19.9 26.9 0.016 13.7 2.1 2.1 2 0 0 2 2 2 2 AAA domain TMF_TATA_bd PF12325.3 EEQ74839.1 - 0.0044 16.7 7.2 0.0044 16.7 5.0 3.9 3 1 1 4 4 4 1 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.3 EEQ74839.1 - 0.0046 16.2 24.3 0.014 14.6 0.3 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF3450) DUF4201 PF13870.1 EEQ74839.1 - 0.11 11.9 48.3 0.014 14.8 11.9 4.5 2 2 1 3 3 3 0 Domain of unknown function (DUF4201) IncA PF04156.9 EEQ74839.1 - 0.28 10.7 41.4 63 3.0 15.7 3.5 1 1 1 2 2 2 0 IncA protein GAS PF13851.1 EEQ74839.1 - 0.76 8.9 39.9 0.2 10.8 4.7 3.8 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF725 PF05267.7 EEQ74839.1 - 2.2 8.2 9.9 0.083 12.8 1.9 2.3 2 2 0 2 2 2 0 Protein of unknown function (DUF725) NPV_P10 PF05531.7 EEQ74839.1 - 4.1 7.7 8.3 11 6.3 1.6 4.0 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein HlyD PF00529.15 EEQ74839.1 - 7.5 5.7 20.2 4.2 6.5 8.7 2.6 2 1 0 2 2 2 0 HlyD family secretion protein XkdW PF09636.5 EEQ74839.1 - 7.6 6.4 10.7 3 7.7 1.9 2.8 2 0 0 2 2 2 0 XkdW protein FliD_N PF02465.13 EEQ74839.1 - 7.7 6.9 22.2 8.1 6.8 0.7 4.4 1 1 2 4 4 4 0 Flagellar hook-associated protein 2 N-terminus M16C_assoc PF08367.6 EEQ74840.1 - 7e-54 182.2 0.0 1.2e-53 181.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EEQ74840.1 - 2.5e-24 85.9 0.0 2e-11 43.9 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EEQ74840.1 - 3.1e-10 39.9 0.0 2.2e-09 37.2 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Methyltransf_11 PF08241.7 EEQ74841.1 - 4.6e-14 52.6 0.0 1.3e-13 51.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ74841.1 - 1.8e-13 50.3 0.0 2.5e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ74841.1 - 3.4e-13 49.6 0.0 9.2e-13 48.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ74841.1 - 1e-11 45.1 0.0 1.8e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ74841.1 - 1.1e-11 45.3 0.0 2.1e-11 44.3 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ74841.1 - 6e-07 29.7 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ74841.1 - 2e-06 27.3 0.0 2.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EEQ74841.1 - 3.1e-06 27.1 0.0 7e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EEQ74841.1 - 2.3e-05 23.2 0.0 3.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.14 EEQ74841.1 - 5.3e-05 22.8 0.0 9.5e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EEQ74841.1 - 0.0001 21.4 0.0 0.00017 20.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 EEQ74841.1 - 0.00013 21.4 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.15 EEQ74841.1 - 0.00027 20.0 0.0 0.00039 19.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DREV PF05219.7 EEQ74841.1 - 0.00051 18.9 0.0 0.00084 18.2 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase CMAS PF02353.15 EEQ74841.1 - 0.001 18.2 0.0 0.0014 17.7 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase TPMT PF05724.6 EEQ74841.1 - 0.0099 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) PrmA PF06325.8 EEQ74841.1 - 0.026 13.6 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EEQ74841.1 - 0.039 13.9 0.0 0.17 11.8 0.0 1.9 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 EEQ74841.1 - 0.086 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EEQ74841.1 - 0.094 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CBAH PF02275.13 EEQ74841.1 - 0.16 11.3 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family DUF202 PF02656.10 EEQ74842.1 - 1e-17 64.1 0.7 1e-17 64.1 0.5 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF202) Cation_efflux PF01545.16 EEQ74843.1 - 5.8e-78 261.8 1.8 1.5e-77 260.4 1.2 1.6 1 1 0 1 1 1 1 Cation efflux family Granulin PF00396.13 EEQ74843.1 - 0.25 11.4 4.1 0.48 10.5 2.8 1.4 1 0 0 1 1 1 0 Granulin Metallophos PF00149.23 EEQ74845.1 - 1.2e-10 41.1 0.1 1.9e-07 30.6 0.0 2.5 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase ODV-E18 PF10717.4 EEQ74846.1 - 0.031 13.7 0.5 0.053 12.9 0.3 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 GET2 PF08690.5 EEQ74846.1 - 0.39 9.9 2.4 0.65 9.1 1.7 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 Tyrosinase PF00264.15 EEQ74849.1 - 1.3e-52 179.1 0.8 2.3e-52 178.3 0.1 1.7 2 0 0 2 2 2 1 Common central domain of tyrosinase Fungal_trans PF04082.13 EEQ74850.1 - 4.6e-20 71.5 0.2 9e-20 70.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Toxin_39 PF15500.1 EEQ74850.1 - 0.017 15.2 0.3 0.039 14.0 0.2 1.5 1 0 0 1 1 1 0 Putative RNase-like toxin Ribosomal_S8e PF01201.17 EEQ74851.1 - 2.1e-34 118.4 4.5 7.7e-34 116.6 3.1 1.8 1 1 0 1 1 1 1 Ribosomal protein S8e Ribosomal_L21p PF00829.16 EEQ74852.1 - 0.026 14.6 0.0 0.041 14.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal prokaryotic L21 protein Herpes_capsid PF06112.6 EEQ74852.1 - 2.2 8.3 6.7 3.6 7.6 4.6 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF822 PF05687.8 EEQ74852.1 - 7.7 6.8 10.2 2.8 8.2 1.1 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF822) Pkinase PF00069.20 EEQ74853.1 - 5.5e-46 156.8 0.0 7.6e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ74853.1 - 3e-17 62.5 0.0 4.6e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EEQ74853.1 - 0.0015 17.9 0.1 0.0036 16.6 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EEQ74853.1 - 0.0063 15.5 0.0 0.0098 14.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEQ74853.1 - 0.2 10.6 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pap_E4 PF02711.9 EEQ74854.1 - 0.37 11.6 4.5 0.59 10.9 3.1 1.5 1 0 0 1 1 1 0 E4 protein Neur_chan_memb PF02932.11 EEQ74854.1 - 0.56 10.0 2.3 0.67 9.8 1.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DDHD PF02862.12 EEQ74854.1 - 0.95 9.2 5.5 1.1 9.0 3.8 1.1 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.9 EEQ74854.1 - 1.2 7.0 7.9 1.3 6.9 5.5 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 EEQ74854.1 - 1.6 8.0 11.9 2.2 7.6 8.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) RR_TM4-6 PF06459.7 EEQ74854.1 - 3.5 7.4 8.9 4.1 7.2 6.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PWI PF01480.12 EEQ74855.1 - 3.2e-22 78.3 0.1 7.7e-22 77.1 0.0 1.7 1 1 0 1 1 1 1 PWI domain Rootletin PF15035.1 EEQ74856.1 - 0.03 14.2 0.5 0.038 13.9 0.3 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Cob_adeno_trans PF01923.13 EEQ74856.1 - 0.14 11.9 0.3 0.34 10.6 0.1 1.7 2 0 0 2 2 2 0 Cobalamin adenosyltransferase FAA_hydrolase PF01557.13 EEQ74857.1 - 1.7e-54 184.5 0.0 2.1e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF605 PF04652.11 EEQ74858.1 - 0.078 12.3 6.8 0.11 11.8 4.7 1.2 1 0 0 1 1 1 0 Vta1 like DEAD PF00270.24 EEQ74859.1 - 1.2e-43 148.5 2.9 1.2e-43 148.4 1.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ74859.1 - 6.2e-28 96.4 0.4 2.3e-27 94.6 0.2 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ74859.1 - 0.00038 20.3 0.1 0.00096 19.0 0.1 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EEQ74859.1 - 0.001 18.1 0.0 0.0022 17.0 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.1 EEQ74859.1 - 0.0011 18.5 0.5 0.0028 17.2 0.1 1.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEQ74859.1 - 0.013 15.2 0.1 0.039 13.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EEQ74859.1 - 0.029 14.5 0.2 0.11 12.5 0.2 2.0 1 1 0 1 1 1 0 AAA domain Fanconi_A PF03511.9 EEQ74859.1 - 0.049 13.4 0.2 0.22 11.3 0.1 2.0 2 0 0 2 2 2 0 Fanconi anaemia group A protein Helicase_RecD PF05127.9 EEQ74859.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Helicase Cupin_8 PF13621.1 EEQ74860.1 - 8.7e-16 58.1 0.0 1.4e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EEQ74860.1 - 1.6e-07 31.5 0.2 0.00089 19.4 0.0 2.4 2 0 0 2 2 2 2 JmjC domain, hydroxylase F-box-like PF12937.2 EEQ74860.1 - 4.7e-05 23.0 0.4 0.00011 21.8 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ74860.1 - 0.002 17.7 0.2 0.0047 16.5 0.1 1.5 1 0 0 1 1 1 1 F-box domain DUF3446 PF11928.3 EEQ74860.1 - 0.026 14.7 3.5 0.083 13.0 2.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Ctr PF04145.10 EEQ74861.1 - 7.1e-17 61.7 0.0 1.1e-16 61.1 0.0 1.3 1 1 0 1 1 1 1 Ctr copper transporter family NuA4 PF09340.5 EEQ74862.1 - 2.9e-27 94.1 0.0 2.9e-27 94.1 0.0 2.1 2 1 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Pneumo_att_G PF05539.6 EEQ74862.1 - 0.17 11.2 11.3 0.23 10.8 7.8 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G AKAP2_C PF15304.1 EEQ74862.1 - 1.6 8.2 11.1 2.4 7.6 7.7 1.2 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus FLO_LFY PF01698.11 EEQ74862.1 - 2 7.1 5.3 2.7 6.7 3.7 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Med3 PF11593.3 EEQ74862.1 - 2.9 7.0 23.7 4.8 6.3 16.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PPP4R2 PF09184.6 EEQ74862.1 - 3.3 7.1 11.0 4.8 6.6 7.7 1.2 1 0 0 1 1 1 0 PPP4R2 NST1 PF13945.1 EEQ74862.1 - 3.5 7.6 9.4 7.8 6.5 6.5 1.6 1 0 0 1 1 1 0 Salt tolerance down-regulator Glyco_hydro_38 PF01074.17 EEQ74863.1 - 1e-90 303.7 0.3 1e-90 303.7 0.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EEQ74863.1 - 4.7e-73 246.5 0.0 1.9e-72 244.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EEQ74863.1 - 5.3e-26 90.6 0.0 1.4e-25 89.2 0.0 1.8 2 0 0 2 2 2 1 Alpha mannosidase, middle domain 7TMR-DISMED2 PF07696.6 EEQ74863.1 - 0.046 13.1 0.1 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 7TMR-DISM extracellular 2 OPT PF03169.10 EEQ74864.1 - 4.9e-72 243.2 47.5 6.2e-72 242.9 33.0 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3671 PF12420.3 EEQ74864.1 - 0.49 10.3 7.4 0.11 12.4 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function DUF3328 PF11807.3 EEQ74865.1 - 1.7e-46 158.6 4.9 2.2e-46 158.2 3.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) CRA_rpt PF07046.6 EEQ74866.1 - 1.5 8.8 8.4 39 4.3 0.2 3.5 1 1 5 6 6 6 0 Cytoplasmic repetitive antigen (CRA) like repeat Pro-kuma_activ PF09286.6 EEQ74867.1 - 3.5e-38 130.8 0.0 5.5e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EEQ74867.1 - 1e-08 34.6 0.1 1.9e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 Subtilase family DUF3328 PF11807.3 EEQ74868.1 - 1.2e-53 182.0 1.1 1.6e-53 181.5 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.11 EEQ74869.1 - 2.3e-13 49.6 17.1 6.6e-08 31.6 0.7 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2077 PF09850.4 EEQ74869.1 - 0.015 14.7 0.1 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) VanZ PF04892.7 EEQ74869.1 - 1.2 9.1 6.1 1.2 9.1 0.8 2.6 2 1 0 2 2 2 0 VanZ like family Pro-kuma_activ PF09286.6 EEQ74871.1 - 6.1e-35 120.3 0.0 2.7e-34 118.2 0.0 1.9 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EEQ74871.1 - 2e-08 33.7 0.0 3.1e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Cytochrom_B561 PF03188.11 EEQ74872.1 - 0.00012 21.8 15.4 0.00028 20.7 10.7 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 EEQ74872.1 - 0.0046 16.5 5.3 0.0046 16.5 3.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF4229 PF14012.1 EEQ74872.1 - 0.0072 16.2 1.6 0.0072 16.2 1.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) FAM177 PF14774.1 EEQ74872.1 - 0.084 12.7 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 FAM177 family DUF204 PF02659.10 EEQ74872.1 - 3.1 8.0 10.5 0.24 11.5 1.2 2.7 2 1 0 2 2 2 0 Domain of unknown function DUF PAT1 PF09770.4 EEQ74873.1 - 2.2 6.3 23.7 3.3 5.8 16.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NUDIX PF00293.23 EEQ74874.1 - 2.4e-12 46.6 0.0 4.8e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain GHL12 PF14882.1 EEQ74874.1 - 0.099 12.7 2.5 0.23 11.5 1.7 1.6 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 12 LETM1 PF07766.8 EEQ74875.1 - 1.6e-105 351.9 0.6 2.9e-105 351.1 0.4 1.4 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 EEQ74875.1 - 1.1e-06 27.9 0.0 0.0011 18.3 0.0 3.1 3 0 0 3 3 3 2 SAP domain DUF2838 PF10998.3 EEQ74876.1 - 2.4e-45 152.9 11.2 2.4e-45 152.9 7.8 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Val_tRNA-synt_C PF10458.4 EEQ74876.1 - 2.4 8.2 5.7 14 5.8 2.6 2.2 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Ank_2 PF12796.2 EEQ74877.1 - 2.5e-25 88.6 14.0 1.1e-10 41.7 0.6 4.8 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ74877.1 - 2.2e-16 58.7 12.2 1.5e-05 24.5 0.0 7.3 6 1 1 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 EEQ74877.1 - 2.8e-15 56.3 4.8 4.4e-07 30.2 0.1 5.5 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ74877.1 - 4.6e-14 51.1 5.3 0.00036 20.5 0.0 7.3 7 1 1 8 8 8 3 Ankyrin repeat Ank_5 PF13857.1 EEQ74877.1 - 2.4e-13 49.8 12.2 0.00024 21.2 0.0 6.8 5 3 3 8 8 8 3 Ankyrin repeats (many copies) SMC_N PF02463.14 EEQ74878.1 - 2.6e-59 200.0 0.0 1.6e-58 197.5 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EEQ74878.1 - 2.7e-31 108.0 0.0 9e-31 106.3 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EEQ74878.1 - 1.6e-10 41.4 11.3 2.6e-05 24.3 0.0 3.6 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EEQ74878.1 - 2.5e-10 41.0 21.2 2.5e-10 41.0 14.7 6.9 3 2 3 6 6 3 1 AAA domain AAA_29 PF13555.1 EEQ74878.1 - 3e-08 33.0 0.0 6.8e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EEQ74878.1 - 0.00068 19.5 0.0 0.0027 17.5 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Reo_sigmaC PF04582.7 EEQ74878.1 - 0.0027 16.9 26.4 0.031 13.4 0.3 4.7 4 1 2 6 6 6 4 Reovirus sigma C capsid protein Tropomyosin PF00261.15 EEQ74878.1 - 0.0042 16.1 18.7 0.0042 16.1 13.0 6.5 4 2 1 5 5 5 3 Tropomyosin DUF4200 PF13863.1 EEQ74878.1 - 0.0045 16.9 9.7 0.0045 16.9 6.7 8.9 4 2 5 9 9 6 2 Domain of unknown function (DUF4200) Laminin_II PF06009.7 EEQ74878.1 - 0.0092 15.7 0.4 0.0092 15.7 0.3 7.5 4 2 2 7 7 7 2 Laminin Domain II TPR_MLP1_2 PF07926.7 EEQ74878.1 - 0.019 14.7 0.9 0.019 14.7 0.6 8.0 4 2 3 7 7 7 0 TPR/MLP1/MLP2-like protein ABC_tran PF00005.22 EEQ74878.1 - 1 9.6 0.0 1 9.6 0.0 6.6 4 3 0 4 4 3 0 ABC transporter Spc7 PF08317.6 EEQ74878.1 - 5.4 5.5 95.5 0.15 10.7 10.2 6.6 3 2 3 6 6 6 0 Spc7 kinetochore protein DUF563 PF04577.9 EEQ74881.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF563) E3_binding PF02817.12 EEQ74882.1 - 2.5e-06 27.0 0.0 7.9e-06 25.4 0.0 1.9 1 0 0 1 1 1 1 e3 binding domain WD40 PF00400.27 EEQ74883.1 - 6.2e-34 114.6 4.4 5.7e-07 29.1 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EEQ74883.1 - 2.1e-06 27.5 0.1 0.0072 16.0 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Peptidase_M18 PF02127.10 EEQ74884.1 - 2e-153 510.9 0.0 2.8e-153 510.4 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) DUF904 PF06005.7 EEQ74885.1 - 0.00027 21.1 6.7 0.00069 19.8 4.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF904) DUF972 PF06156.8 EEQ74885.1 - 0.0033 17.7 4.7 0.0071 16.6 3.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF972) HALZ PF02183.13 EEQ74885.1 - 0.0067 16.1 3.3 0.019 14.6 2.3 1.8 1 0 0 1 1 1 1 Homeobox associated leucine zipper Rab5-bind PF09311.6 EEQ74885.1 - 0.0097 15.8 6.9 0.011 15.6 3.0 2.2 2 0 0 2 2 2 1 Rabaptin-like protein DUF3972 PF13118.1 EEQ74885.1 - 0.027 14.5 3.2 0.052 13.6 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) TSC22 PF01166.13 EEQ74885.1 - 0.036 14.0 2.8 0.3 11.0 2.1 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family XkdW PF09636.5 EEQ74885.1 - 0.041 13.7 1.5 0.088 12.6 1.0 1.5 1 0 0 1 1 1 0 XkdW protein ADIP PF11559.3 EEQ74885.1 - 0.076 12.9 9.6 0.18 11.7 6.7 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EEQ74885.1 - 0.15 11.6 2.4 0.25 10.9 1.6 1.3 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EEQ74885.1 - 0.33 10.4 1.6 0.89 9.0 1.1 1.7 1 0 0 1 1 1 0 Septum formation initiator V_ATPase_I PF01496.14 EEQ74885.1 - 2.2 6.0 3.8 3.7 5.2 2.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-H PF05837.7 EEQ74885.1 - 9.2 6.5 10.7 0.71 10.0 3.7 2.0 2 0 0 2 2 2 0 Centromere protein H (CENP-H) HSP70 PF00012.15 EEQ74886.1 - 5.9e-14 50.9 1.3 3.1e-11 41.9 0.3 2.3 2 1 0 2 2 2 2 Hsp70 protein FtsA PF14450.1 EEQ74886.1 - 0.022 14.6 5.8 0.21 11.4 1.9 3.0 2 1 0 2 2 2 0 Cell division protein FtsA Hydantoinase_A PF01968.13 EEQ74886.1 - 0.031 13.3 2.2 0.26 10.3 1.5 2.2 1 1 0 1 1 1 0 Hydantoinase/oxoprolinase DUF1746 PF08508.5 EEQ74887.1 - 5.5e-43 145.5 1.2 1e-42 144.7 0.8 1.4 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) CLP_protease PF00574.18 EEQ74888.1 - 1.3e-73 246.5 0.0 1.6e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 Clp protease Clr5 PF14420.1 EEQ74888.1 - 0.0023 17.7 0.6 0.0045 16.8 0.4 1.4 1 0 0 1 1 1 1 Clr5 domain Hydrolase_6 PF13344.1 EEQ74890.1 - 2.4e-28 97.9 0.0 3.8e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ74890.1 - 7.3e-13 48.0 0.0 1.4e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EEQ74890.1 - 1.7e-12 48.2 0.0 2.3e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EEQ74890.1 - 1.7e-05 25.0 0.1 0.00073 19.7 0.1 2.6 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 EEQ74890.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) AAA PF00004.24 EEQ74891.1 - 8.3e-15 55.1 0.0 1.9e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EEQ74891.1 - 4.9e-13 49.0 0.0 8.7e-12 44.9 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 EEQ74891.1 - 2e-12 46.8 0.0 4.6e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 EEQ74891.1 - 2.4e-11 43.0 0.0 1.7e-08 33.5 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EEQ74891.1 - 2.1e-06 27.8 0.1 7.8e-05 22.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EEQ74891.1 - 7.2e-06 25.2 0.0 1.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EEQ74891.1 - 3.2e-05 23.6 0.0 4.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ74891.1 - 4.5e-05 23.1 0.0 0.00012 21.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EEQ74891.1 - 4.9e-05 23.3 0.3 0.0016 18.4 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.16 EEQ74891.1 - 0.00014 21.1 0.0 0.0049 16.0 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EEQ74891.1 - 0.00047 20.0 0.0 0.00088 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EEQ74891.1 - 0.0013 17.8 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.1 EEQ74891.1 - 0.0013 18.3 0.4 0.0039 16.8 0.1 1.9 3 0 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EEQ74891.1 - 0.0046 16.4 0.0 0.012 15.0 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF815 PF05673.8 EEQ74891.1 - 0.0076 15.2 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EEQ74891.1 - 0.0081 15.8 0.2 0.11 12.1 0.1 2.5 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EEQ74891.1 - 0.012 15.0 0.2 0.037 13.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EEQ74891.1 - 0.013 16.3 0.2 0.08 13.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EEQ74891.1 - 0.033 14.1 0.0 0.071 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EEQ74891.1 - 0.035 13.7 0.0 0.43 10.1 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EEQ74891.1 - 0.037 13.4 0.1 0.55 9.6 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain AAA_23 PF13476.1 EEQ74891.1 - 0.046 14.0 0.0 0.069 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEQ74891.1 - 0.052 13.8 0.0 0.14 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EEQ74891.1 - 0.066 12.4 0.0 3.1 6.9 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.1 EEQ74891.1 - 0.074 12.6 0.0 0.39 10.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.18 EEQ74891.1 - 0.09 11.5 0.0 1.7 7.3 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain DEAD PF00270.24 EEQ74891.1 - 0.13 11.7 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase DNA_pol3_delta PF06144.8 EEQ74891.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit ResIII PF04851.10 EEQ74891.1 - 0.15 11.8 0.0 0.41 10.4 0.0 1.6 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Sec20 PF03908.8 EEQ74892.1 - 5.6e-16 58.0 1.5 1.4e-15 56.7 1.0 1.7 1 0 0 1 1 1 1 Sec20 MRP_L53 PF10780.4 EEQ74893.1 - 7e-15 54.7 0.1 1e-14 54.2 0.1 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Pyrophosphatase PF00719.14 EEQ74894.1 - 2.6e-51 173.1 0.2 3.3e-51 172.8 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Dus PF01207.12 EEQ74895.1 - 3.8e-44 150.7 0.0 5.4e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) FCP1_C PF09309.5 EEQ74895.1 - 0.033 13.4 0.5 0.056 12.7 0.3 1.3 1 0 0 1 1 1 0 FCP1, C-terminal Peptidase_M28 PF04389.12 EEQ74896.1 - 4.5e-33 114.4 0.0 7.1e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EEQ74896.1 - 5.3e-06 26.0 0.0 8.5e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PA PF02225.17 EEQ74896.1 - 0.0006 19.4 0.5 0.0062 16.2 0.0 2.5 2 1 0 2 2 2 1 PA domain Nicastrin PF05450.10 EEQ74896.1 - 0.015 14.5 0.1 0.05 12.8 0.0 1.7 2 0 0 2 2 2 0 Nicastrin Peptidase_M42 PF05343.9 EEQ74896.1 - 0.037 12.8 0.0 0.2 10.3 0.0 1.9 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase SNF2_N PF00176.18 EEQ74898.1 - 3.5e-58 196.7 0.1 5.8e-58 196.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ74898.1 - 3.5e-14 52.4 0.0 1.1e-13 50.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ74898.1 - 6e-08 32.7 0.0 1.5e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EEQ74898.1 - 2.7e-06 26.9 0.0 6.6e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HHH_3 PF12836.2 EEQ74898.1 - 0.0031 17.3 0.1 0.009 15.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif VMA21 PF09446.5 EEQ74899.1 - 1.2e-08 34.7 7.0 2.4e-08 33.7 4.8 1.5 1 1 0 1 1 1 1 VMA21-like domain DUF2970 PF11174.3 EEQ74899.1 - 0.29 10.7 1.4 1.9 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Ribosomal_L35Ae PF01247.13 EEQ74901.1 - 8.9e-35 118.3 0.3 1.1e-34 118.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EEQ74901.1 - 7.6e-05 22.5 0.0 0.22 11.4 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain DIOX_N PF14226.1 EEQ74902.1 - 3.5e-15 56.5 0.0 6e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EEQ74902.1 - 1.9e-13 50.5 0.0 3.7e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RRN9 PF10680.4 EEQ74902.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor SRF-TF PF00319.13 EEQ74903.1 - 5e-24 83.2 0.1 7.8e-24 82.6 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Glyco_hydro_18 PF00704.23 EEQ74905.1 - 3.6e-75 253.5 3.1 6.9e-75 252.6 2.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EEQ74905.1 - 0.004 17.1 4.9 0.004 17.1 3.4 4.6 4 1 0 4 4 4 2 Chitin recognition protein Glyco_hydro_85 PF03644.8 EEQ74905.1 - 0.005 16.0 0.0 0.0084 15.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 DUF1708 PF08101.6 EEQ74908.1 - 1.2e-162 541.5 0.0 1.6e-162 541.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF3602 PF12223.3 EEQ74909.1 - 3.2e-12 46.6 16.2 2.1e-07 31.2 1.3 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) gag_pre-integrs PF13976.1 EEQ74910.1 - 3e-08 33.1 0.3 8.2e-08 31.7 0.2 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain FAD_binding_3 PF01494.14 EEQ74911.1 - 1e-89 301.1 0.0 1.3e-89 300.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EEQ74911.1 - 5e-05 23.2 0.2 0.00024 21.0 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEQ74911.1 - 0.0041 16.0 0.0 0.54 9.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EEQ74911.1 - 0.02 15.2 0.1 0.64 10.4 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEQ74911.1 - 0.069 12.0 0.4 0.1 11.4 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Homeobox_KN PF05920.6 EEQ74911.1 - 0.074 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Homeobox KN domain NAD_binding_8 PF13450.1 EEQ74911.1 - 0.086 12.8 1.6 0.24 11.4 1.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EEQ74911.1 - 0.12 12.3 0.3 0.28 11.2 0.2 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EEQ74911.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.11 EEQ74912.1 - 6.1e-36 123.8 59.3 1.6e-26 92.8 25.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily YrvL PF14184.1 EEQ74912.1 - 1 9.1 3.8 43 3.8 1.3 3.0 3 0 0 3 3 3 0 Regulatory protein YrvL Mito_carr PF00153.22 EEQ74913.1 - 9.9e-48 159.8 6.1 2.8e-18 65.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1065 PF06358.6 EEQ74913.1 - 0.053 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1065) CBS PF00571.23 EEQ74914.1 - 0.00068 19.3 0.0 3.1 7.6 0.0 3.1 2 1 1 3 3 3 2 CBS domain MFS_2 PF13347.1 EEQ74915.1 - 4.1e-09 35.3 10.6 4.1e-09 35.3 7.3 2.4 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 EEQ74915.1 - 0.36 10.6 4.4 4 7.2 0.0 3.6 3 0 0 3 3 3 0 MFS_1 like family Amastin PF07344.6 EEQ74915.1 - 0.42 10.2 8.5 1.7 8.2 0.5 3.1 3 0 0 3 3 3 0 Amastin surface glycoprotein ABC2_membrane PF01061.19 EEQ74916.1 - 2.9e-88 294.5 60.2 1e-45 155.5 17.7 3.4 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EEQ74916.1 - 1e-38 132.7 0.0 4.8e-18 65.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EEQ74916.1 - 9.1e-38 128.0 6.8 4.7e-33 112.9 0.0 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 EEQ74916.1 - 2.1e-23 82.1 0.0 7.8e-23 80.3 0.0 2.0 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EEQ74916.1 - 1.9e-06 27.4 0.0 0.00089 18.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EEQ74916.1 - 2.6e-05 23.4 0.0 0.00079 18.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EEQ74916.1 - 4.1e-05 23.6 0.2 0.00035 20.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.2 EEQ74916.1 - 0.00023 20.3 18.4 0.00023 20.3 12.8 3.3 2 2 1 3 3 3 1 ABC-2 family transporter protein AAA_33 PF13671.1 EEQ74916.1 - 0.00029 20.7 0.0 0.065 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EEQ74916.1 - 0.00047 19.6 1.2 0.018 14.5 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EEQ74916.1 - 0.00077 19.7 0.0 0.026 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EEQ74916.1 - 0.0038 16.4 0.0 0.91 8.7 0.0 3.4 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EEQ74916.1 - 0.0048 17.7 0.0 0.41 11.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EEQ74916.1 - 0.0051 16.2 0.6 0.039 13.3 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EEQ74916.1 - 0.0084 16.2 0.0 0.93 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EEQ74916.1 - 0.0091 15.9 0.0 2.1 8.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 EEQ74916.1 - 0.032 13.9 2.4 2.8 7.5 0.1 2.9 3 0 0 3 3 3 0 NACHT domain UPF0079 PF02367.12 EEQ74916.1 - 0.11 12.1 1.1 9.1 5.9 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 EEQ74916.1 - 0.12 11.7 0.2 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Miro PF08477.8 EEQ74916.1 - 0.17 12.4 0.0 22 5.5 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 EEQ74916.1 - 0.26 10.7 0.5 2.7 7.4 0.1 2.5 3 0 0 3 3 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 EEQ74916.1 - 0.28 10.7 0.2 5 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EEQ74916.1 - 0.29 10.5 1.9 22 4.3 0.1 3.4 3 0 0 3 3 3 0 AAA-like domain G6PD_C PF02781.11 EEQ74918.1 - 1.8e-135 450.4 0.0 2.4e-135 450.0 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EEQ74918.1 - 1.6e-63 214.2 0.0 3.2e-63 213.2 0.0 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain MFS_1 PF07690.11 EEQ74920.1 - 1.3e-45 155.6 44.0 9e-45 152.9 30.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ74920.1 - 4.2e-28 97.9 16.3 4.2e-28 97.9 11.3 1.8 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEQ74920.1 - 1.2e-11 43.8 7.7 1.2e-11 43.8 5.3 3.5 1 1 2 3 3 3 1 Sugar (and other) transporter Pox_A14 PF05767.7 EEQ74920.1 - 3.3 7.7 7.1 20 5.2 0.7 3.7 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 EF-hand_1 PF00036.27 EEQ74921.1 - 1.4e-20 70.9 5.4 3.3e-07 29.1 0.2 4.5 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EEQ74921.1 - 2e-18 64.5 3.9 2.8e-05 23.6 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 EEQ74921.1 - 2.2e-18 66.1 0.4 6.3e-09 35.8 0.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EEQ74921.1 - 8.8e-18 63.6 3.4 8.8e-08 31.6 0.1 4.1 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EEQ74921.1 - 6.7e-13 47.3 4.6 0.00026 20.1 0.1 4.1 4 0 0 4 4 4 3 EF hand DUF1282 PF06930.7 EEQ74921.1 - 0.058 13.0 0.1 0.45 10.1 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1282) ChaC PF04752.7 EEQ74922.1 - 4e-28 98.5 0.0 6.6e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 ChaC-like protein RRM_1 PF00076.17 EEQ74923.1 - 1e-22 79.5 0.0 1.4e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ74923.1 - 5.2e-16 58.3 0.0 6.7e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ74923.1 - 2.3e-10 40.1 0.0 3.1e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pheromone PF08015.6 EEQ74925.1 - 4.9 8.0 7.7 3.7 8.4 0.8 3.9 2 1 0 2 2 2 0 Fungal mating-type pheromone eIF-5_eIF-2B PF01873.12 EEQ74930.1 - 2.3e-43 146.8 0.3 3.7e-43 146.1 0.2 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 EEQ74930.1 - 0.076 13.3 0.6 0.27 11.5 0.4 2.0 1 1 0 1 1 1 0 Restriction alleviation protein Lar PAT1 PF09770.4 EEQ74930.1 - 0.11 10.7 1.9 0.17 10.1 1.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Arc_trans_TRASH PF08394.5 EEQ74930.1 - 1.2 9.3 7.1 1.1 9.4 0.2 2.8 1 1 1 2 2 2 0 Archaeal TRASH domain Tyrosinase PF00264.15 EEQ74931.1 - 1.2e-37 130.1 1.2 1.6e-37 129.8 0.8 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF3927 PF13064.1 EEQ74932.1 - 0.15 11.5 0.4 0.24 10.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3927) AIM24 PF01987.12 EEQ74933.1 - 1.3e-53 181.7 0.2 1.5e-53 181.4 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 SH3_1 PF00018.23 EEQ74934.1 - 6.4e-14 51.0 0.0 1.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEQ74934.1 - 6.2e-11 41.7 0.0 9.7e-11 41.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EEQ74934.1 - 7.7e-09 34.9 0.0 1.2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain MBF1 PF08523.5 EEQ74936.1 - 1.4e-23 82.6 0.1 2.2e-23 82.0 0.1 1.3 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EEQ74936.1 - 9.4e-07 28.5 0.1 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 EEQ74936.1 - 0.0019 18.1 0.1 0.0028 17.6 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 EEQ74936.1 - 0.0027 17.8 0.0 0.0057 16.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain IBN_N PF03810.14 EEQ74937.1 - 3.8e-05 23.5 0.9 0.039 13.8 0.1 4.2 3 1 1 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EEQ74937.1 - 0.00047 20.0 4.8 0.021 14.7 0.0 3.9 4 0 0 4 4 4 2 Exportin 1-like protein HEAT_2 PF13646.1 EEQ74937.1 - 0.024 14.8 0.7 0.23 11.7 0.0 3.0 3 0 0 3 3 3 0 HEAT repeats SH3_2 PF07653.12 EEQ74938.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain Pkinase PF00069.20 EEQ74939.1 - 1.9e-77 259.9 0.0 2.1e-77 259.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ74939.1 - 8.9e-38 129.8 0.0 1.2e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EEQ74939.1 - 6e-05 22.4 0.2 9.4e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EEQ74939.1 - 0.0006 18.8 0.6 0.0042 16.0 0.2 2.4 1 1 2 3 3 3 1 Kinase-like APH PF01636.18 EEQ74939.1 - 0.0099 15.6 1.0 0.016 14.9 0.1 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ74939.1 - 0.018 14.0 0.5 0.018 14.0 0.3 1.9 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EEQ74939.1 - 0.027 14.0 0.1 0.039 13.5 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 EEQ74939.1 - 0.03 13.1 0.1 0.052 12.3 0.1 1.4 1 1 0 1 1 1 0 Seadornavirus VP7 Cellulase PF00150.13 EEQ74940.1 - 3.7e-09 36.1 1.8 3.2e-06 26.5 0.3 2.4 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) TPR_11 PF13414.1 EEQ74941.1 - 1.4e-52 175.2 31.5 6.2e-07 28.9 0.0 13.5 12 2 1 13 13 13 9 TPR repeat TPR_2 PF07719.12 EEQ74941.1 - 6.4e-29 97.5 51.0 0.0069 16.2 0.0 17.7 19 0 0 19 19 18 8 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ74941.1 - 1.1e-28 97.6 32.6 0.003 17.0 0.0 15.9 16 1 0 16 16 16 6 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ74941.1 - 6.2e-28 94.7 43.0 0.0025 18.2 0.5 17.5 13 7 7 20 20 19 6 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ74941.1 - 8.8e-28 94.1 4.3 0.19 11.9 0.0 14.5 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ74941.1 - 5e-27 93.9 50.5 4e-06 27.3 0.3 12.5 14 1 0 14 14 10 6 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ74941.1 - 1.2e-22 79.6 41.9 1.3e-05 25.0 0.1 13.3 9 3 7 16 16 15 8 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ74941.1 - 5.1e-22 77.9 30.7 0.00097 19.4 0.5 12.2 11 2 2 13 13 13 7 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ74941.1 - 1e-21 75.0 21.6 0.35 10.7 0.0 14.4 15 1 1 16 16 14 6 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ74941.1 - 3.2e-15 54.6 26.0 0.0016 18.1 0.0 13.6 15 0 0 15 15 14 2 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ74941.1 - 1.6e-13 50.1 21.8 0.14 12.6 0.0 13.8 16 0 0 16 16 15 3 Tetratricopeptide repeat Apc3 PF12895.2 EEQ74941.1 - 2.6e-10 40.3 14.4 0.0035 17.4 0.1 7.8 7 1 1 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EEQ74941.1 - 1.2e-07 31.5 14.4 0.13 12.1 0.0 7.9 7 2 1 8 8 8 2 Tetratricopeptide repeat Coatomer_E PF04733.9 EEQ74941.1 - 0.0058 15.8 0.5 0.025 13.7 0.0 2.4 2 0 0 2 2 2 1 Coatomer epsilon subunit Coatomer_WDAD PF04053.9 EEQ74941.1 - 0.017 13.9 0.1 0.92 8.2 0.0 2.3 2 0 0 2 2 2 0 Coatomer WD associated region Fis1_TPR_C PF14853.1 EEQ74941.1 - 0.23 11.3 4.8 17 5.4 0.0 5.0 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.9 EEQ74941.1 - 6.7 7.4 25.5 35 5.2 0.4 9.0 10 0 0 10 10 8 0 Tetratricopeptide repeat DUF1767 PF08585.7 EEQ74942.1 - 8.2e-17 61.2 0.1 1.5e-16 60.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Vps51 PF08700.6 EEQ74943.1 - 1.1e-24 86.0 0.0 2.1e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.4 EEQ74943.1 - 0.0037 17.2 0.1 0.0078 16.1 0.0 1.5 1 1 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.7 EEQ74943.1 - 0.031 12.7 0.1 0.04 12.3 0.1 1.1 1 0 0 1 1 1 0 Dor1-like family FlgN PF05130.7 EEQ74943.1 - 0.28 11.4 3.9 1.1 9.4 0.0 2.4 1 1 0 2 2 2 0 FlgN protein DUF1917 PF08939.5 EEQ74944.1 - 2e-65 220.9 0.0 2.3e-65 220.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) WD40 PF00400.27 EEQ74945.1 - 0.029 14.2 1.5 18 5.3 0.0 4.6 6 0 0 6 6 6 0 WD domain, G-beta repeat SAC3_GANP PF03399.11 EEQ74946.1 - 1.4e-15 57.3 0.4 2.2e-15 56.8 0.2 1.4 1 1 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EEQ74946.1 - 1.2e-11 44.5 0.1 9.2e-11 41.6 0.0 2.1 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 Pro-kuma_activ PF09286.6 EEQ74947.1 - 1.7e-36 125.3 0.0 2.7e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EEQ74947.1 - 9.8e-06 24.9 0.1 1.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Subtilase family TBCC PF07986.7 EEQ74948.1 - 1.5e-31 108.2 0.2 2.7e-31 107.4 0.2 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C JAB PF01398.16 EEQ74949.1 - 1.2e-15 57.2 0.0 3.2e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 EEQ74949.1 - 2.7e-09 37.0 0.2 5.6e-09 35.9 0.2 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 EEQ74949.1 - 5.6e-06 25.8 0.1 2.4e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain MIT PF04212.13 EEQ74949.1 - 0.093 12.6 1.1 0.18 11.7 0.8 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain RrnaAD PF00398.15 EEQ74950.1 - 1.6e-06 27.3 0.0 6e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Pkinase PF00069.20 EEQ74952.1 - 1.2e-13 50.8 0.0 2.6e-13 49.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ74952.1 - 8.5e-06 25.0 0.0 0.0018 17.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Ank_2 PF12796.2 EEQ74953.1 - 2.8e-40 136.5 2.6 7.3e-15 55.0 0.0 4.7 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ74953.1 - 2.3e-23 80.7 9.8 0.0004 20.0 0.0 9.2 9 0 0 9 9 9 6 Ankyrin repeat Ank_3 PF13606.1 EEQ74953.1 - 8.8e-15 53.3 2.3 0.018 15.2 0.0 7.7 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.1 EEQ74953.1 - 1.9e-12 46.9 1.0 4.7e-05 23.4 0.0 5.7 4 1 4 8 8 8 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEQ74953.1 - 4.1e-12 46.2 1.0 8.5e-05 22.9 0.0 5.9 5 3 1 6 6 6 2 Ankyrin repeats (many copies) Phage_T7_Capsid PF05396.6 EEQ74953.1 - 0.16 12.1 0.0 35 4.5 0.0 2.8 2 1 0 2 2 2 0 Phage T7 capsid assembly protein ApbA_C PF08546.6 EEQ74954.1 - 1.4e-28 99.4 0.0 2.2e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EEQ74954.1 - 1.2e-26 92.9 0.0 1.7e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EEQ74954.1 - 0.0083 15.9 2.3 0.036 13.8 1.2 2.1 2 0 0 2 2 2 1 ThiF family GFO_IDH_MocA PF01408.17 EEQ74954.1 - 0.034 14.6 0.1 0.099 13.1 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Clr5 PF14420.1 EEQ74955.1 - 9.7e-08 31.8 4.1 2.9e-07 30.2 2.8 1.8 1 0 0 1 1 1 1 Clr5 domain PAT1 PF09770.4 EEQ74955.1 - 0.012 13.8 28.1 0.019 13.2 19.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EEQ74955.1 - 0.022 14.1 19.2 0.037 13.4 13.3 1.3 1 0 0 1 1 1 0 Vta1 like TAXi_C PF14541.1 EEQ74955.1 - 0.065 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Pox_G5 PF04599.7 EEQ74955.1 - 0.068 11.8 0.1 1.5 7.4 0.0 2.2 1 1 1 2 2 2 0 Poxvirus G5 protein Zip PF02535.17 EEQ74955.1 - 0.13 11.2 13.2 0.21 10.5 9.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter MDFI PF15316.1 EEQ74955.1 - 6.5 6.7 7.4 23 4.9 0.2 2.5 2 0 0 2 2 2 0 MyoD family inhibitor TFIIA PF03153.8 EEQ74955.1 - 7.7 6.3 25.2 2.6 7.8 13.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RP-C_C PF11800.3 EEQ74955.1 - 8.7 5.9 18.7 3 7.4 7.7 2.9 1 1 0 2 2 2 0 Replication protein C C-terminal region Med25_SD1 PF11235.3 EEQ74956.1 - 3.5 7.9 11.1 0.095 13.0 1.6 2.3 1 1 1 2 2 2 0 Mediator complex subunit 25 synapsin 1 IATP PF04568.7 EEQ74956.1 - 7.7 6.6 11.9 3 7.9 5.3 2.4 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Phytase-like PF13449.1 EEQ74958.1 - 5.6e-29 101.4 0.0 9.5e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 Esterase-like activity of phytase SdiA-regulated PF06977.6 EEQ74958.1 - 0.14 11.0 0.0 2.2 7.1 0.0 2.5 2 0 0 2 2 2 0 SdiA-regulated Coatomer_WDAD PF04053.9 EEQ74961.1 - 1.4e-147 492.0 0.0 2.1e-147 491.5 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EEQ74961.1 - 1.2e-97 327.1 0.0 1.8e-97 326.5 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EEQ74961.1 - 2.4e-48 160.3 12.8 8.8e-09 34.9 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EEQ74961.1 - 0.0044 15.2 6.1 0.53 8.3 0.0 3.5 1 1 2 4 4 4 2 Nucleoporin Nup120/160 Clathrin PF00637.15 EEQ74961.1 - 0.036 13.6 0.2 0.37 10.3 0.0 2.7 2 1 1 3 3 3 0 Region in Clathrin and VPS Evr1_Alr PF04777.8 EEQ74962.1 - 1.9e-28 98.2 2.4 6.6e-28 96.4 1.2 1.9 2 0 0 2 2 2 1 Erv1 / Alr family Bd3614-deam PF14439.1 EEQ74962.1 - 0.032 14.0 0.1 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Bd3614-like deaminase Dicty_REP PF05086.7 EEQ74962.1 - 0.66 7.6 3.6 0.97 7.1 2.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DEK_C PF08766.6 EEQ74963.1 - 0.0042 16.8 0.6 0.012 15.4 0.2 1.9 2 0 0 2 2 2 1 DEK C terminal domain MIP-T3 PF10243.4 EEQ74963.1 - 4.7 5.5 42.9 5.9 5.2 29.7 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Adaptin_N PF01602.15 EEQ74964.1 - 1.6e-146 488.7 1.5 2.1e-146 488.3 1.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EEQ74964.1 - 2.5e-28 99.1 0.2 1.4e-25 90.1 0.0 2.8 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EEQ74964.1 - 2.2e-17 63.0 2.1 1.4e-06 28.4 0.0 5.7 3 1 4 7 7 7 4 HEAT repeats HEAT PF02985.17 EEQ74964.1 - 1.6e-11 43.2 4.4 0.003 17.5 0.0 5.4 6 0 0 6 6 6 3 HEAT repeat Arm PF00514.18 EEQ74964.1 - 0.00028 20.5 0.8 1.2 9.0 0.0 4.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EEQ74964.1 - 0.00077 19.8 5.6 4.4 7.9 0.0 6.7 7 1 1 8 8 8 1 HEAT-like repeat Ribosomal_60s PF00428.14 EEQ74964.1 - 2.4 8.6 10.5 6.5 7.2 6.0 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein TLD PF07534.11 EEQ74965.1 - 2.9e-24 85.6 0.1 8.1e-15 55.0 0.0 2.6 3 0 0 3 3 3 2 TLD VID27 PF08553.5 EEQ74966.1 - 0 1115.7 0.6 0 1115.4 0.4 1.1 1 0 0 1 1 1 1 VID27 cytoplasmic protein tRNA_m1G_MT PF01746.16 EEQ74967.1 - 1.5e-30 106.1 0.0 7.8e-30 103.8 0.0 2.1 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase NARP1 PF12569.3 EEQ74967.1 - 0.19 10.4 7.1 0.33 9.6 4.9 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 BRF1 PF07741.8 EEQ74967.1 - 0.78 10.0 10.2 2.7 8.2 7.1 2.0 1 0 0 1 1 1 0 Brf1-like TBP-binding domain GRIM-19 PF06212.7 EEQ74968.1 - 5.5e-22 77.8 0.1 1.1e-21 76.8 0.1 1.5 1 1 0 1 1 1 1 GRIM-19 protein Iso_dh PF00180.15 EEQ74969.1 - 2.1e-70 237.3 0.0 2.4e-70 237.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DHFR_2 PF06442.6 EEQ74969.1 - 0.15 11.6 0.0 7.1 6.3 0.0 2.5 2 0 0 2 2 2 0 R67 dihydrofolate reductase FTHFS PF01268.14 EEQ74971.1 - 1.3e-255 848.7 0.1 1.8e-255 848.2 0.1 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EEQ74971.1 - 2.5e-69 231.4 1.2 2.5e-69 231.4 0.8 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EEQ74971.1 - 4.6e-37 126.6 0.1 1.8e-36 124.7 0.2 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain WD40 PF00400.27 EEQ74972.1 - 4.6e-30 102.3 0.5 2.1e-09 36.8 0.0 6.3 6 1 0 6 6 6 5 WD domain, G-beta repeat Gmad1 PF10647.4 EEQ74972.1 - 0.0012 18.2 0.1 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 EEQ74972.1 - 0.036 12.2 0.0 0.064 11.3 0.0 1.4 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Het-C PF07217.6 EEQ74973.1 - 1.5e-261 868.9 0.0 1.5e-261 868.9 0.0 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein Het-C DUF2828 PF11443.3 EEQ74974.1 - 9.5e-182 604.9 0.0 1.1e-181 604.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) FAD-oxidase_C PF02913.14 EEQ74976.1 - 3.5e-57 193.5 0.0 5.6e-57 192.8 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EEQ74976.1 - 7.6e-38 129.1 0.0 1.3e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_2 PF00703.16 EEQ74977.1 - 1.3e-10 41.6 0.6 4.5e-10 39.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EEQ74977.1 - 6.1e-10 38.8 0.0 2.5e-09 36.8 0.0 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EEQ74977.1 - 0.0037 16.2 0.0 0.0074 15.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF2451 PF10474.4 EEQ74977.1 - 0.058 13.1 0.1 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) ADH_N PF08240.7 EEQ74978.1 - 8.1e-31 106.0 0.3 1.6e-30 105.0 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ74978.1 - 2.4e-23 82.1 0.6 4e-23 81.3 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EEQ74978.1 - 0.00013 21.4 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.2 EEQ74978.1 - 0.0013 19.3 0.0 0.0022 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AlaDh_PNT_C PF01262.16 EEQ74978.1 - 0.0031 17.0 0.5 0.0051 16.4 0.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.16 EEQ74978.1 - 0.054 13.3 0.5 0.12 12.2 0.3 1.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PrmA PF06325.8 EEQ74978.1 - 0.061 12.4 0.1 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) 2-Hacid_dh_C PF02826.14 EEQ74978.1 - 0.068 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ras PF00071.17 EEQ74979.1 - 2.3e-40 137.6 0.0 4.8e-40 136.5 0.0 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EEQ74979.1 - 1.7e-13 51.1 0.0 2.7e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ74979.1 - 6.4e-11 41.7 0.0 3.3e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEQ74979.1 - 0.00015 21.2 0.0 0.00077 18.9 0.0 2.1 2 1 0 2 2 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EEQ74979.1 - 0.00017 20.8 0.0 0.00023 20.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEQ74979.1 - 0.002 18.0 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EEQ74979.1 - 0.003 17.0 0.0 0.22 11.0 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 EEQ74979.1 - 0.0046 16.8 0.0 0.0095 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EEQ74979.1 - 0.0049 16.0 0.0 0.0075 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EEQ74979.1 - 0.0058 15.8 0.0 0.015 14.5 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EEQ74979.1 - 0.0093 16.1 0.0 0.024 14.7 0.0 1.7 2 1 0 2 2 1 1 AAA domain ABC_tran PF00005.22 EEQ74979.1 - 0.017 15.3 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 EEQ74979.1 - 0.024 14.5 0.0 0.073 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain IL11 PF07400.6 EEQ74979.1 - 0.034 13.6 0.0 9.5 5.6 0.0 2.2 2 0 0 2 2 2 0 Interleukin 11 AAA_16 PF13191.1 EEQ74979.1 - 0.042 13.8 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 EEQ74979.1 - 0.062 12.9 0.1 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.1 EEQ74979.1 - 0.07 12.6 0.0 0.21 11.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 EEQ74979.1 - 0.11 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EEQ74979.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase PAF-AH_p_II PF03403.8 EEQ74980.1 - 1.4e-39 135.5 0.0 3.3e-38 130.9 0.0 2.1 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EEQ74980.1 - 2.1e-05 24.3 0.0 9e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 EEQ74980.1 - 0.00024 20.0 0.0 0.00046 19.0 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 EEQ74980.1 - 0.0014 17.5 0.0 0.0027 16.6 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 EEQ74980.1 - 0.0089 15.9 1.8 0.22 11.3 1.2 2.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ74981.1 - 2.1e-18 67.0 0.0 2.6e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ74981.1 - 5.7e-15 55.5 0.0 3.9e-14 52.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ74981.1 - 5.4e-07 29.4 0.0 1.7e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EEQ74981.1 - 0.0019 16.7 0.0 0.0054 15.2 0.0 1.7 1 1 0 1 1 1 1 Ndr family PhoPQ_related PF10142.4 EEQ74981.1 - 0.01 14.3 0.0 0.024 13.1 0.0 1.6 2 0 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein Na_Ca_ex PF01699.19 EEQ74984.1 - 4.3e-38 130.0 34.8 4.7e-22 78.0 10.1 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein ETRAMP PF09716.5 EEQ74984.1 - 0.51 10.3 2.5 1.2 9.1 0.0 3.0 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Glyco_tranf_2_3 PF13641.1 EEQ74987.1 - 1.2e-22 80.8 0.0 1.6e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EEQ74987.1 - 2.3e-12 46.9 0.0 3.9e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EEQ74987.1 - 2.8e-05 23.4 0.0 0.0002 20.7 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 ATP12 PF07542.6 EEQ74988.1 - 3.4e-36 123.8 0.1 6.6e-36 122.9 0.1 1.5 1 0 0 1 1 1 1 ATP12 chaperone protein Oxysterol_BP PF01237.13 EEQ74989.1 - 1.8e-135 450.9 0.0 7.2e-135 449.0 0.0 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 EEQ74989.1 - 3.1e-24 85.1 0.0 6.8e-11 42.3 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEQ74989.1 - 8.7e-18 63.9 0.1 6.6e-11 42.0 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EEQ74989.1 - 1.8e-15 55.8 0.1 7.4e-06 25.5 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EEQ74989.1 - 3.2e-15 56.1 0.1 2.8e-07 30.8 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ74989.1 - 2.8e-14 51.7 0.0 1.2e-05 25.0 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat PH PF00169.24 EEQ74989.1 - 1.1e-10 41.6 0.2 2.3e-10 40.5 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EEQ74989.1 - 3.6e-09 36.8 0.7 1e-08 35.3 0.5 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EEQ74989.1 - 6.9e-07 29.2 0.8 1.7e-06 27.9 0.6 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Uds1 PF15456.1 EEQ74989.1 - 0.036 14.0 3.5 0.57 10.1 0.1 3.1 2 0 0 2 2 2 0 Up-regulated During Septation zf-Mss51 PF13824.1 EEQ74990.1 - 3.1e-28 97.3 5.8 3.1e-28 97.3 4.0 2.4 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 EEQ74990.1 - 0.016 15.0 0.4 0.016 15.0 0.3 1.9 2 0 0 2 2 2 0 MYND finger GFA PF04828.9 EEQ74990.1 - 0.051 13.5 0.5 0.22 11.5 0.1 2.2 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-HIT PF04438.11 EEQ74990.1 - 0.42 10.2 2.2 0.89 9.2 0.3 2.2 2 0 0 2 2 2 0 HIT zinc finger ADH_zinc_N PF00107.21 EEQ74992.1 - 2.5e-31 107.9 0.8 4.1e-31 107.2 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEQ74992.1 - 3.9e-08 34.2 0.0 3.9e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEQ74992.1 - 1.9e-07 30.7 0.0 1.2e-06 28.2 0.0 2.3 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain Pep_deformylase PF01327.16 EEQ74992.1 - 0.06 12.7 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 Polypeptide deformylase HET PF06985.6 EEQ74993.1 - 5e-31 107.7 0.0 7.6e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) 4F5 PF04419.9 EEQ74995.1 - 0.065 13.9 0.1 0.53 11.0 0.1 2.2 2 0 0 2 2 2 0 4F5 protein family Clr5 PF14420.1 EEQ74996.1 - 1.9e-11 43.6 0.2 3e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 Clr5 domain SNF2_N PF00176.18 EEQ74997.1 - 7.4e-73 244.9 0.9 1.6e-72 243.8 0.6 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ74997.1 - 3.9e-15 55.4 0.1 1.1e-14 54.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ74997.1 - 8.7e-08 32.2 0.3 3.5e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EEQ74997.1 - 1.3e-07 31.2 0.0 9.5e-06 25.2 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase HSA PF07529.8 EEQ74997.1 - 1.2e-05 24.9 7.0 5.2e-05 22.9 4.8 2.1 1 0 0 1 1 1 1 HSA TAP35_44 PF07265.6 EEQ74997.1 - 0.036 13.8 2.3 0.13 11.9 1.6 2.0 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 NDUF_B8 PF05821.6 EEQ74998.1 - 3.8e-05 23.4 0.0 4.4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Membr_traf_MHD PF10540.4 EEQ74999.1 - 7.1e-26 90.6 0.1 4.1e-25 88.1 0.0 2.3 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EEQ74999.1 - 6.8e-16 57.8 0.0 1.6e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.6 EEQ74999.1 - 2.2e-06 26.2 2.5 6.2e-06 24.7 0.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF810) BATS PF06968.8 EEQ75001.1 - 2e-30 104.4 0.1 1.2e-29 101.9 0.0 2.3 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EEQ75001.1 - 1.4e-16 61.1 0.1 4.2e-16 59.5 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily DUF1205 PF06722.7 EEQ75001.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1205) Plectin PF00681.15 EEQ75001.1 - 0.12 11.9 0.1 11 5.6 0.0 2.6 2 0 0 2 2 2 0 Plectin repeat Aminotran_3 PF00202.16 EEQ75002.1 - 1.8e-41 142.1 0.0 2.3e-23 82.5 0.0 2.6 2 0 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 EEQ75002.1 - 5.3e-31 107.7 0.0 9.1e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Aminotran_1_2 PF00155.16 EEQ75003.1 - 4e-33 114.8 0.0 4.6e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EEQ75003.1 - 0.0036 15.6 0.0 0.0056 15.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EEQ75003.1 - 0.008 14.9 0.0 0.51 9.0 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V PilJ PF13675.1 EEQ75003.1 - 0.11 12.8 0.1 0.31 11.3 0.0 1.7 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term MFS_1 PF07690.11 EEQ75004.1 - 3.1e-13 49.1 22.8 3.1e-13 49.1 15.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EEQ75004.1 - 2.4e-08 33.6 5.2 5.7e-08 32.4 3.6 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 DUF2909 PF11137.3 EEQ75004.1 - 0.81 9.4 3.8 1.4 8.7 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2909) TauD PF02668.11 EEQ75005.1 - 1.2e-34 120.1 0.1 1.6e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Tht1 PF04163.7 EEQ75006.1 - 1.6e-09 36.7 0.1 1.6e-09 36.7 0.1 2.0 1 1 0 2 2 2 1 Tht1-like nuclear fusion protein Ribosomal_L6 PF00347.18 EEQ75007.1 - 7.1e-23 80.9 0.2 2.6e-13 50.2 0.0 2.7 3 0 0 3 3 3 2 Ribosomal protein L6 Inositol_P PF00459.20 EEQ75008.1 - 1.4e-55 188.5 0.3 2.5e-55 187.7 0.2 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family VHS PF00790.14 EEQ75009.1 - 1.4e-19 70.1 0.0 3e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EEQ75009.1 - 6.2e-12 45.3 1.3 1.3e-11 44.3 0.9 1.5 1 0 0 1 1 1 1 GAT domain DEAD PF00270.24 EEQ75010.1 - 6.9e-44 149.3 0.0 1.8e-43 147.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ75010.1 - 1.7e-21 75.8 0.0 6.2e-21 74.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EEQ75010.1 - 0.033 14.3 0.1 0.1 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain FtsJ PF01728.14 EEQ75011.1 - 1.2e-62 211.1 0.0 1.6e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase FAD_binding_1 PF00667.15 EEQ75012.1 - 4.6e-64 215.8 0.0 7.4e-64 215.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EEQ75012.1 - 1.9e-11 44.4 0.0 5.3e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 EEQ75012.1 - 6.3e-08 32.7 0.0 1.3e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 EEQ75012.1 - 0.00011 22.1 0.0 0.00029 20.7 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain TMF_TATA_bd PF12325.3 EEQ75014.1 - 0.047 13.4 2.9 1.1 8.9 0.6 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4635 PF15466.1 EEQ75014.1 - 0.11 11.8 1.8 0.12 11.6 1.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4635) Proteasome PF00227.21 EEQ75015.1 - 1.1e-59 200.9 0.1 1.3e-59 200.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEQ75015.1 - 3.4e-14 51.8 0.2 6.9e-14 50.8 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 EEQ75015.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit FF PF01846.14 EEQ75016.1 - 1.2e-11 44.4 9.6 1.1e-08 34.9 0.2 3.6 3 0 0 3 3 3 3 FF domain WW PF00397.21 EEQ75016.1 - 0.0001 22.0 1.8 0.00072 19.3 0.3 2.6 2 0 0 2 2 2 1 WW domain Cwf_Cwc_15 PF04889.7 EEQ75017.1 - 1.3 8.6 31.2 0.02 14.6 8.6 2.2 1 1 1 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PAT1 PF09770.4 EEQ75017.1 - 2.2 6.4 21.0 2.9 6.0 14.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIS_M PF07500.9 EEQ75018.1 - 1.3e-22 80.0 0.1 4.1e-22 78.4 0.0 1.9 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 EEQ75018.1 - 1.1e-18 67.7 0.0 2e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 EEQ75018.1 - 1.4e-10 40.7 12.5 2.3e-10 39.9 8.7 1.4 1 0 0 1 1 1 1 PHD-finger Terminase_GpA PF05876.7 EEQ75018.1 - 0.0085 14.4 5.5 0.014 13.7 3.8 1.2 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) PHD_2 PF13831.1 EEQ75018.1 - 0.081 12.2 4.5 0.13 11.5 3.1 1.4 1 0 0 1 1 1 0 PHD-finger PHD_3 PF13922.1 EEQ75018.1 - 1.3 9.3 13.7 0.078 13.2 4.4 2.7 2 1 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx LUC7 PF03194.10 EEQ75019.1 - 1.6e-72 244.0 0.2 2e-72 243.7 0.1 1.0 1 0 0 1 1 1 1 LUC7 N_terminus MCPsignal PF00015.16 EEQ75019.1 - 0.0065 16.0 0.0 0.0095 15.4 0.0 1.2 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3735 PF12537.3 EEQ75019.1 - 0.022 14.7 0.1 0.48 10.4 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3735) DASH_Duo1 PF08651.5 EEQ75019.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 Gpi16 PF04113.9 EEQ75020.1 - 2.6e-240 798.2 0.0 3.1e-240 797.9 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component HECT PF00632.20 EEQ75023.1 - 4.9e-84 282.1 0.0 1.1e-83 281.0 0.0 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Clr5 PF14420.1 EEQ75023.1 - 0.14 12.0 0.1 0.35 10.8 0.1 1.6 1 0 0 1 1 1 0 Clr5 domain HEAT PF02985.17 EEQ75023.1 - 0.15 12.2 0.5 2.8 8.2 0.0 3.5 4 0 0 4 4 4 0 HEAT repeat SAPS PF04499.10 EEQ75023.1 - 2.3 6.7 17.1 0.58 8.7 6.7 3.0 2 1 0 2 2 2 0 SIT4 phosphatase-associated protein Arm PF00514.18 EEQ75023.1 - 4.4 7.2 9.7 6.5 6.7 0.1 5.2 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat CTP_transf_2 PF01467.21 EEQ75024.1 - 2.3e-25 89.5 0.0 3e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase HAD PF12710.2 EEQ75025.1 - 1.1e-10 42.0 0.0 1.5e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EEQ75025.1 - 0.00038 19.8 0.0 0.001 18.4 0.0 1.8 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 EEQ75025.1 - 0.00083 19.6 0.0 0.0025 18.0 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EEQ75025.1 - 0.0057 15.8 0.0 0.31 10.1 0.1 2.1 2 0 0 2 2 2 2 Putative Phosphatase RVT_1 PF00078.22 EEQ75026.1 - 5.6e-08 32.3 0.0 1.5e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mit_ribos_Mrp51 PF11709.3 EEQ75026.1 - 2.6 7.1 5.1 0.63 9.1 0.2 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit TFR_dimer PF04253.10 EEQ75029.1 - 2.3e-17 62.7 0.0 4.4e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EEQ75029.1 - 1.2e-15 57.7 0.0 2.5e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EEQ75029.1 - 0.00016 21.2 0.2 0.00072 19.2 0.0 2.1 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.10 EEQ75029.1 - 0.0089 15.2 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Nicastrin Peptidase_M20 PF01546.23 EEQ75029.1 - 0.062 12.7 0.0 0.092 12.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 ApoB100_C PF12491.3 EEQ75029.1 - 0.14 11.8 0.1 2.6 7.7 0.0 2.6 3 0 0 3 3 3 0 Apolipoprotein B100 C terminal BTB PF00651.26 EEQ75030.1 - 9.7e-06 25.5 0.0 1.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain SIS PF01380.17 EEQ75032.1 - 2.2e-12 46.7 0.0 5.2e-12 45.5 0.0 1.7 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 EEQ75032.1 - 0.00011 21.9 0.0 0.0006 19.5 0.0 2.1 1 1 1 2 2 2 1 SIS domain PLRV_ORF5 PF01690.12 EEQ75032.1 - 0.33 10.0 0.6 0.49 9.4 0.4 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Ubie_methyltran PF01209.13 EEQ75033.1 - 5.7e-82 274.3 0.0 7.2e-82 273.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EEQ75033.1 - 1.4e-16 60.4 0.0 1.9e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ75033.1 - 6.7e-14 52.1 0.0 1.3e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ75033.1 - 1.3e-09 38.3 0.0 2.8e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ75033.1 - 1.3e-09 38.4 0.0 2.2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ75033.1 - 1.6e-08 34.3 0.0 2.5e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ75033.1 - 2.1e-08 34.7 0.0 3.6e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ75033.1 - 3.6e-05 23.7 0.0 7.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EEQ75033.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans_2 PF11951.3 EEQ75035.1 - 4.5e-38 130.8 0.2 5.9e-38 130.4 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ75035.1 - 1.5e-08 34.3 8.9 2.7e-08 33.5 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Uso1_p115_head PF04869.9 EEQ75035.1 - 0.061 12.0 0.0 0.089 11.5 0.0 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region Ldl_recept_a PF00057.13 EEQ75035.1 - 0.43 10.5 4.3 0.76 9.7 3.0 1.3 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A Exo_endo_phos PF03372.18 EEQ75038.1 - 1.1e-08 35.3 0.4 1.4e-08 35.0 0.2 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2537 PF10801.3 EEQ75040.1 - 0.3 11.2 3.6 1.5 8.9 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2537) DAO PF01266.19 EEQ75041.1 - 1.2e-11 44.1 0.0 1.5e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase E1_dh PF00676.15 EEQ75042.1 - 2.7e-85 285.6 0.0 3.3e-85 285.4 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EEQ75042.1 - 0.00011 21.7 0.1 0.0014 18.2 0.1 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.5 EEQ75042.1 - 0.0089 14.6 0.0 0.016 13.8 0.0 1.3 1 0 0 1 1 1 1 XFP N-terminal domain DUF1470 PF07336.6 EEQ75042.1 - 0.03 14.6 0.4 0.084 13.2 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1470) DXP_synthase_N PF13292.1 EEQ75042.1 - 0.063 12.2 0.0 0.17 10.7 0.0 1.7 1 1 1 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase FlaC_arch PF05377.6 EEQ75043.1 - 0.22 11.4 2.2 0.47 10.3 1.5 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) zf-RING_4 PF14570.1 EEQ75044.1 - 3.2e-19 68.2 13.4 5.5e-19 67.4 9.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 EEQ75044.1 - 2.1e-05 24.0 0.0 4.7e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 EEQ75044.1 - 3e-05 23.6 7.5 5.3e-05 22.8 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 EEQ75044.1 - 0.00025 20.8 0.0 0.00061 19.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 EEQ75044.1 - 0.00087 19.0 5.0 0.0016 18.1 3.5 1.3 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.20 EEQ75044.1 - 0.093 12.4 12.7 0.19 11.4 8.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ75044.1 - 0.66 10.0 11.9 1.2 9.2 8.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EEQ75044.1 - 4.8 6.3 10.8 0.022 14.0 0.8 2.0 3 0 0 3 3 3 0 Rtf2 RING-finger Complex1_30kDa PF00329.14 EEQ75045.1 - 2.2e-33 114.5 0.1 3.5e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Fungal_trans PF04082.13 EEQ75048.1 - 3.4e-22 78.5 0.2 3.4e-22 78.5 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain BUD22 PF09073.5 EEQ75049.1 - 8.3e-88 295.3 9.3 1.1e-87 294.9 6.4 1.1 1 0 0 1 1 1 1 BUD22 PP1c_bdg PF10488.4 EEQ75049.1 - 0.09 11.9 5.9 0.14 11.3 4.1 1.3 1 0 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region NPV_P10 PF05531.7 EEQ75050.1 - 0.011 15.9 1.4 0.011 15.9 1.0 6.6 4 2 3 7 7 7 0 Nucleopolyhedrovirus P10 protein HTH_34 PF13601.1 EEQ75050.1 - 1.1 9.3 9.1 5.8 7.0 0.0 4.4 4 0 0 4 4 4 0 Winged helix DNA-binding domain MitMem_reg PF13012.1 EEQ75050.1 - 1.7 8.7 38.9 0.98 9.5 2.5 5.4 1 1 2 4 4 4 0 Maintenance of mitochondrial structure and function PNP_UDP_1 PF01048.15 EEQ75051.1 - 6e-37 126.8 0.2 7.6e-37 126.5 0.2 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Glyco_hydro_3 PF00933.16 EEQ75052.1 - 3.6e-90 301.9 0.0 4.9e-90 301.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EEQ75052.1 - 3e-52 177.3 0.0 2.7e-51 174.2 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EEQ75052.1 - 6.3e-20 70.8 0.1 1.1e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF572 PF04502.8 EEQ75054.1 - 1.8e-50 171.9 0.0 3.4e-50 171.1 0.0 1.3 1 1 0 1 1 1 1 Family of unknown function (DUF572) B_lectin PF01453.19 EEQ75054.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 D-mannose binding lectin PTPA PF03095.10 EEQ75055.1 - 2.7e-114 381.4 0.0 3.1e-114 381.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein AgrD PF05931.6 EEQ75056.1 - 0.091 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Staphylococcal AgrD protein Tropomyosin_1 PF12718.2 EEQ75059.1 - 1.4e-05 24.9 13.9 1.4e-05 24.9 9.6 9.6 1 1 7 10 10 10 3 Tropomyosin like HR1 PF02185.11 EEQ75059.1 - 3.1e-05 23.6 0.9 3.1e-05 23.6 0.6 12.7 7 3 6 14 14 14 2 Hr1 repeat Filament PF00038.16 EEQ75059.1 - 0.0015 18.0 20.0 0.0015 18.0 13.8 7.7 1 1 4 5 5 5 2 Intermediate filament protein Fib_alpha PF08702.5 EEQ75059.1 - 0.0047 17.0 1.1 0.0047 17.0 0.7 9.1 2 1 4 9 9 9 3 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.7 EEQ75059.1 - 0.0051 16.5 26.3 0.0051 16.5 18.2 10.1 2 1 5 9 9 9 4 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 EEQ75059.1 - 0.0093 15.7 6.9 0.0093 15.7 4.8 15.5 5 1 9 16 16 16 3 TATA element modulatory factor 1 DNA binding DUF1409 PF07197.7 EEQ75059.1 - 0.022 14.8 1.2 0.022 14.8 0.8 6.8 8 0 0 8 8 8 0 Protein of unknown function (DUF1409) Snapin_Pallidin PF14712.1 EEQ75059.1 - 0.056 13.7 0.1 0.056 13.7 0.1 10.1 6 3 4 12 12 12 0 Snapin/Pallidin Reo_sigmaC PF04582.7 EEQ75059.1 - 0.11 11.6 79.4 0.016 14.3 7.1 7.9 2 1 7 9 9 9 0 Reovirus sigma C capsid protein BHD_3 PF10405.4 EEQ75061.1 - 3.8e-26 90.5 0.0 7.3e-26 89.6 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EEQ75061.1 - 1.3e-19 69.4 0.1 2.8e-19 68.3 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Rad4 PF03835.10 EEQ75061.1 - 3.7e-19 68.5 0.2 9.6e-19 67.2 0.1 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_2 PF10404.4 EEQ75061.1 - 1.6e-14 53.9 0.1 7.3e-14 51.8 0.1 2.2 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EEQ75061.1 - 0.041 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Transglutaminase-like superfamily Dicty_REP PF05086.7 EEQ75061.1 - 0.68 7.6 4.7 1.3 6.7 3.2 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PAT1 PF09770.4 EEQ75061.1 - 5.2 5.1 15.1 8.4 4.4 10.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BSD PF03909.12 EEQ75063.1 - 5e-17 61.3 1.1 1e-16 60.3 0.8 1.6 1 0 0 1 1 1 1 BSD domain Ran-binding PF05508.6 EEQ75064.1 - 2.2e-85 286.2 0.1 3.2e-85 285.6 0.1 1.2 1 0 0 1 1 1 1 RanGTP-binding protein GTP_EFTU PF00009.22 EEQ75065.1 - 5.8e-43 146.5 0.0 8.1e-43 146.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EEQ75065.1 - 4.8e-20 71.5 0.1 1.4e-19 70.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EEQ75065.1 - 3e-09 36.8 0.3 6.4e-09 35.8 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 G-alpha PF00503.15 EEQ75065.1 - 0.003 16.3 0.1 0.0053 15.4 0.1 1.4 1 0 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.18 EEQ75065.1 - 0.0041 17.0 0.0 0.0094 15.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase WGG PF10273.4 EEQ75066.1 - 3.5e-31 107.1 0.1 5.8e-31 106.4 0.0 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 KfrA_N PF11740.3 EEQ75066.1 - 0.039 14.4 0.1 0.074 13.5 0.0 1.4 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Ribosomal_60s PF00428.14 EEQ75066.1 - 0.044 14.1 0.8 0.08 13.3 0.5 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Abhydrolase_3 PF07859.8 EEQ75067.1 - 2.4e-14 53.4 0.1 5.8e-06 26.0 0.0 3.4 2 1 1 3 3 3 3 alpha/beta hydrolase fold DUF2424 PF10340.4 EEQ75067.1 - 0.014 14.0 0.0 0.38 9.3 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2424) COesterase PF00135.23 EEQ75067.1 - 0.14 10.8 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family ParA PF10609.4 EEQ75068.1 - 6e-32 109.3 0.0 1.2e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EEQ75068.1 - 2.8e-14 52.9 0.0 4.2e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EEQ75068.1 - 2.1e-08 34.2 0.0 7.4e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EEQ75068.1 - 5.2e-06 25.7 0.1 7.7e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 EEQ75068.1 - 0.0011 18.1 0.2 0.0038 16.3 0.3 1.7 3 0 0 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.1 EEQ75068.1 - 0.0019 17.6 0.0 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EEQ75068.1 - 0.0055 15.9 0.0 0.082 12.0 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family APS_kinase PF01583.15 EEQ75068.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase VirC1 PF07015.6 EEQ75068.1 - 0.19 10.8 0.1 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein TRAUB PF08164.7 EEQ75069.1 - 1.8e-32 111.2 1.6 3e-32 110.5 0.0 2.3 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EEQ75069.1 - 6e-32 110.5 2.8 6e-32 110.5 1.9 2.6 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor RR_TM4-6 PF06459.7 EEQ75069.1 - 4.6 7.0 10.4 11 5.7 6.5 2.3 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 adh_short_C2 PF13561.1 EEQ75070.1 - 9.2e-12 45.2 0.0 1.1e-11 44.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEQ75070.1 - 0.008 16.1 0.1 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase DUF4537 PF15057.1 EEQ75071.1 - 0.0028 17.4 0.0 0.0048 16.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) DUF1325 PF07039.6 EEQ75071.1 - 0.014 14.9 0.4 0.038 13.6 0.0 1.8 1 1 1 2 2 2 0 SGF29 tudor-like domain TUDOR PF00567.19 EEQ75071.1 - 0.035 13.9 0.0 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 Tudor domain FH2 PF02181.18 EEQ75071.1 - 0.14 10.9 0.5 0.19 10.5 0.3 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain Fungal_trans_2 PF11951.3 EEQ75073.1 - 3.1e-06 26.0 0.4 0.0021 16.7 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain adh_short PF00106.20 EEQ75074.1 - 1.3e-13 51.1 0.0 2.1e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ75074.1 - 1.6e-05 24.6 0.0 3.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 KR domain peroxidase PF00141.18 EEQ75074.1 - 0.058 12.8 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Peroxidase Polysacc_synt_2 PF02719.10 EEQ75074.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PAP1 PF08601.5 EEQ75077.1 - 2.6e-67 228.0 30.8 2.6e-67 228.0 21.4 3.1 3 1 0 3 3 3 1 Transcription factor PAP1 bZIP_1 PF00170.16 EEQ75077.1 - 1.6e-09 37.5 11.9 3.2e-09 36.6 8.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EEQ75077.1 - 0.012 15.9 8.7 0.03 14.6 6.0 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor Glutaredoxin2_C PF04399.8 EEQ75077.1 - 0.17 11.4 1.7 0.32 10.5 1.2 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain IncA PF04156.9 EEQ75077.1 - 0.26 10.8 6.5 0.46 10.0 4.5 1.4 1 0 0 1 1 1 0 IncA protein Adeno_PIX PF03955.9 EEQ75077.1 - 1.1 9.8 4.4 0.48 10.9 0.7 2.1 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) bZIP_2 PF07716.10 EEQ75077.1 - 5.6 6.8 24.7 0.14 12.0 11.6 2.4 2 1 0 2 2 2 0 Basic region leucine zipper DUF2433 PF10360.4 EEQ75078.1 - 4.8e-55 185.4 0.0 9.1e-55 184.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.2 EEQ75078.1 - 0.0089 15.8 0.0 0.022 14.6 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EEQ75078.1 - 0.023 14.0 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase DUF2360 PF10152.4 EEQ75078.1 - 2.3 8.5 11.0 74 3.6 7.6 3.0 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Peptidase_M35 PF02102.10 EEQ75079.1 - 2.2e-83 279.8 5.7 2.8e-83 279.5 4.0 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EEQ75079.1 - 1.3e-06 29.0 0.8 7.4e-06 26.5 0.1 2.2 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase Patched PF02460.13 EEQ75081.1 - 8.9e-76 255.4 8.0 1.6e-50 171.9 0.0 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 EEQ75081.1 - 3.6e-51 172.6 5.1 3.6e-51 172.6 3.5 2.7 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 EEQ75081.1 - 1.9e-07 30.1 22.9 1.6e-06 27.1 5.9 3.3 3 0 0 3 3 3 2 MMPL family HEAT PF02985.17 EEQ75082.1 - 4.9e-22 75.9 1.6 0.00053 19.8 0.0 9.9 9 0 0 9 9 9 5 HEAT repeat HEAT_2 PF13646.1 EEQ75082.1 - 1.4e-21 76.5 7.8 1.4e-05 25.2 0.0 8.0 6 2 2 8 8 8 4 HEAT repeats HEAT_EZ PF13513.1 EEQ75082.1 - 2e-17 63.1 16.9 0.00022 21.6 0.0 10.9 10 3 4 14 14 12 5 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EEQ75082.1 - 3.8e-10 40.0 0.2 0.54 10.6 0.0 7.2 7 2 2 9 9 7 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EEQ75082.1 - 7.6e-08 32.4 0.4 0.12 12.2 0.0 4.7 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 EEQ75082.1 - 8.3e-08 32.0 2.2 5.5e-07 29.3 0.1 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.3 EEQ75082.1 - 2.3e-05 23.8 0.0 0.081 12.2 0.0 3.0 2 1 1 3 3 3 3 CLASP N terminal MMS19_C PF12460.3 EEQ75082.1 - 4.4e-05 22.3 0.4 0.015 14.0 0.0 3.9 4 1 0 4 4 4 1 RNAPII transcription regulator C-terminal Adaptin_N PF01602.15 EEQ75082.1 - 5.6e-05 21.6 0.0 0.12 10.7 0.0 3.0 2 1 0 2 2 2 2 Adaptin N terminal region ParcG PF10274.4 EEQ75082.1 - 7e-05 22.7 0.1 0.042 13.7 0.1 3.3 3 1 0 3 3 3 1 Parkin co-regulated protein UME PF08064.8 EEQ75082.1 - 0.00019 21.3 0.0 0.88 9.5 0.0 4.9 5 1 1 6 6 6 1 UME (NUC010) domain UNC45-central PF11701.3 EEQ75082.1 - 0.0021 17.6 0.9 0.2 11.3 0.3 3.8 3 1 1 4 4 4 1 Myosin-binding striated muscle assembly central Arm PF00514.18 EEQ75082.1 - 0.0023 17.6 0.0 6.2 6.8 0.0 4.6 4 0 0 4 4 3 1 Armadillo/beta-catenin-like repeat Ipi1_N PF12333.3 EEQ75082.1 - 0.043 13.7 0.4 18 5.3 0.0 4.1 5 0 0 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation ADH_zinc_N_2 PF13602.1 EEQ75083.1 - 1.3e-16 61.6 0.0 3.6e-16 60.2 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EEQ75083.1 - 5.2e-09 35.7 0.0 1e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 EEQ75083.1 - 0.025 14.5 0.1 0.049 13.6 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain ADH_N PF08240.7 EEQ75083.1 - 0.11 12.2 0.0 4.5 7.0 0.0 2.7 2 1 1 3 3 3 0 Alcohol dehydrogenase GroES-like domain COesterase PF00135.23 EEQ75087.1 - 4.8e-107 358.8 0.0 6.4e-107 358.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEQ75087.1 - 3e-07 30.2 0.4 1.2e-06 28.2 0.3 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold PEX11 PF05648.9 EEQ75088.1 - 1.5e-29 102.9 0.1 1.9e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) F-actin_cap_A PF01267.12 EEQ75089.1 - 1.3e-94 316.2 0.0 1.5e-94 316.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Reo_sigmaC PF04582.7 EEQ75091.1 - 0.0015 17.7 0.3 0.0018 17.4 0.2 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein T4SS PF07996.6 EEQ75091.1 - 0.011 15.6 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion system proteins NPV_P10 PF05531.7 EEQ75091.1 - 0.017 15.3 0.7 0.026 14.7 0.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF722 PF05263.6 EEQ75091.1 - 0.046 13.8 0.0 0.056 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF722) DUF4140 PF13600.1 EEQ75091.1 - 0.05 14.0 0.6 0.061 13.7 0.4 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF2999 PF11212.3 EEQ75091.1 - 0.051 13.6 0.1 0.097 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) DUF4254 PF14063.1 EEQ75091.1 - 0.066 12.8 0.3 0.082 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) HAUS2 PF15003.1 EEQ75091.1 - 0.076 12.0 0.1 0.084 11.9 0.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 Adeno_PIX PF03955.9 EEQ75091.1 - 0.098 13.1 0.8 2.4 8.7 0.3 2.1 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) PAP2 PF01569.16 EEQ75093.1 - 1e-05 25.2 13.7 0.00012 21.7 9.5 2.7 1 1 0 1 1 1 1 PAP2 superfamily DUF3040 PF11239.3 EEQ75093.1 - 0.79 9.8 2.8 8.6 6.4 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) RseC_MucC PF04246.7 EEQ75093.1 - 1.3 8.5 8.8 0.59 9.7 0.4 2.9 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC NACHT PF05729.7 EEQ75094.1 - 1.1e-06 28.3 0.0 7.5e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EEQ75094.1 - 1.3e-06 28.5 0.0 1e-05 25.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EEQ75094.1 - 0.0002 21.4 0.6 0.00056 19.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EEQ75094.1 - 0.012 15.2 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase Med7 PF05983.6 EEQ75095.1 - 5.1e-61 205.1 0.7 6.7e-61 204.7 0.5 1.1 1 0 0 1 1 1 1 MED7 protein YfcL PF08891.6 EEQ75095.1 - 0.12 12.3 0.3 0.24 11.4 0.2 1.5 1 0 0 1 1 1 0 YfcL protein K_trans PF02705.11 EEQ75096.1 - 1.5e-152 508.7 14.5 1.7e-76 257.7 4.5 2.0 2 0 0 2 2 2 2 K+ potassium transporter Cyt-b5 PF00173.23 EEQ75097.1 - 4.7e-23 80.7 0.0 5.8e-23 80.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain GTP_EFTU PF00009.22 EEQ75098.1 - 1.1e-50 171.6 0.0 1.9e-50 170.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EEQ75098.1 - 6.2e-23 80.7 1.9 1.2e-22 79.7 1.3 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.12 EEQ75098.1 - 3.6e-07 30.2 0.0 1.5e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 EEQ75098.1 - 4.7e-07 29.7 0.0 1.4e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EEQ75098.1 - 2.2e-06 27.6 0.0 5.5e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.17 EEQ75098.1 - 0.00012 21.5 0.1 0.0027 17.0 0.0 2.3 1 1 1 2 2 2 1 Ras family Gtr1_RagA PF04670.7 EEQ75098.1 - 0.00013 21.1 0.0 0.00034 19.8 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EEQ75098.1 - 0.00026 21.4 0.1 0.0015 18.9 0.0 2.4 2 1 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 EEQ75098.1 - 0.0072 15.6 0.0 0.23 10.7 0.0 2.8 2 1 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.5 EEQ75098.1 - 0.023 13.9 0.0 2 7.5 0.0 2.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit MobB PF03205.9 EEQ75098.1 - 0.034 13.8 0.0 0.093 12.4 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 EEQ75098.1 - 0.046 12.4 0.6 0.085 11.5 0.4 1.4 1 0 0 1 1 1 0 G-protein alpha subunit HSP70 PF00012.15 EEQ75099.1 - 1.9e-262 871.6 11.9 2.1e-262 871.4 8.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEQ75099.1 - 3.4e-16 58.7 1.8 1.9e-15 56.3 0.4 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 EEQ75099.1 - 0.0041 16.0 0.3 0.041 12.7 0.1 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 EEQ75099.1 - 0.016 14.3 3.7 0.24 10.4 0.1 3.1 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase DNase_NucA_NucB PF14040.1 EEQ75100.1 - 6.3e-05 23.1 0.1 6.3e-05 23.1 0.0 2.7 2 1 1 3 3 3 1 Deoxyribonuclease NucA/NucB Mucin PF01456.12 EEQ75100.1 - 0.0039 16.9 16.7 0.0075 16.0 11.6 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein Dicty_REP PF05086.7 EEQ75100.1 - 0.097 10.4 3.1 0.13 9.9 2.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein UCH PF00443.24 EEQ75102.1 - 1.7e-58 197.8 0.0 2.5e-58 197.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEQ75102.1 - 1.9e-27 96.5 0.0 2.7e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase VHS PF00790.14 EEQ75103.1 - 1.5e-40 138.1 0.2 4.1e-39 133.4 0.0 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 EEQ75103.1 - 2.1e-16 59.5 2.2 3.7e-16 58.7 1.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EEQ75103.1 - 3.2e-06 26.2 7.5 0.0053 16.2 1.0 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif FYVE_2 PF02318.11 EEQ75103.1 - 0.073 12.9 0.3 0.16 11.8 0.2 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger zf-DHHC PF01529.15 EEQ75103.1 - 0.084 12.2 0.1 0.084 12.2 0.1 1.9 2 1 0 2 2 2 0 DHHC palmitoyltransferase RIG-I_C-RD PF11648.3 EEQ75103.1 - 0.13 12.0 0.1 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 C-terminal domain of RIG-I DGF-1_C PF11040.3 EEQ75103.1 - 0.21 11.5 4.4 11 6.0 0.0 3.7 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus TCO89 PF10452.4 EEQ75104.1 - 4.6e-07 29.1 10.6 2.4e-05 23.4 0.1 2.6 3 0 0 3 3 3 2 TORC1 subunit TCO89 Macoilin PF09726.4 EEQ75104.1 - 4.8 5.3 9.3 10 4.2 6.4 1.5 1 1 0 1 1 1 0 Transmembrane protein RCC1 PF00415.13 EEQ75106.1 - 8.4e-24 83.5 0.3 8.5e-08 32.2 0.0 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EEQ75106.1 - 4.2e-15 55.6 0.0 1.1e-07 31.7 0.0 2.8 3 0 0 3 3 3 2 BTB/POZ domain RCC1_2 PF13540.1 EEQ75106.1 - 2.2e-09 36.6 1.1 7.5e-09 34.9 0.1 2.5 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 EEQ75106.1 - 2.5e-09 37.3 0.1 8.1e-07 29.4 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEQ75106.1 - 8.2e-06 26.0 0.3 0.00015 22.0 0.0 2.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EEQ75106.1 - 1.3e-05 24.9 0.1 0.1 12.8 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EEQ75106.1 - 0.00046 20.3 0.1 0.33 11.2 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 EEQ75106.1 - 0.0017 18.0 0.2 0.098 12.5 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat ATG13 PF10033.4 EEQ75108.1 - 4.9e-69 232.3 0.0 1.7e-68 230.5 0.0 2.0 3 0 0 3 3 3 1 Autophagy-related protein 13 ECH PF00378.15 EEQ75111.1 - 1.8e-23 82.9 0.0 4.2e-23 81.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family NUC153 PF08159.7 EEQ75112.1 - 5.9e-15 54.5 2.7 1.5e-14 53.2 1.9 1.7 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EEQ75112.1 - 7.5e-06 25.6 0.1 0.083 12.8 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat Med13_C PF06333.7 EEQ75113.1 - 3.8e-119 397.9 0.1 3.8e-119 397.9 0.1 2.0 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 EEQ75113.1 - 2e-32 112.4 0.3 2e-32 112.4 0.2 1.7 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal Amidase PF01425.16 EEQ75114.1 - 7.3e-44 150.3 5.8 2.7e-31 108.8 3.8 2.3 1 1 1 2 2 2 2 Amidase Ribosomal_L33 PF00471.15 EEQ75118.1 - 7.5e-05 22.8 0.0 9.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 Apo-CIII PF05778.7 EEQ75119.1 - 0.0062 15.8 3.0 0.1 11.9 0.4 3.7 3 0 0 3 3 3 1 Apolipoprotein CIII (Apo-CIII) CENP-F_leu_zip PF10473.4 EEQ75119.1 - 0.008 16.0 9.2 0.008 16.0 6.4 8.2 2 2 6 8 8 8 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EEQ75119.1 - 0.082 12.0 57.7 0.39 9.8 4.1 5.7 1 1 4 6 6 6 0 Reovirus sigma C capsid protein CALCOCO1 PF07888.6 EEQ75119.1 - 8.2 4.5 100.3 0.3 9.3 35.3 3.8 1 1 3 4 4 4 0 Calcium binding and coiled-coil domain (CALCOCO1) like PET PF06297.9 EEQ75120.1 - 0.053 13.1 0.7 0.59 9.8 0.1 2.2 1 1 1 2 2 2 0 PET Domain Shisa PF13908.1 EEQ75120.1 - 0.053 13.6 0.0 0.074 13.2 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator FAM163 PF15069.1 EEQ75120.1 - 0.14 12.7 0.0 0.21 12.1 0.0 1.2 1 0 0 1 1 1 0 FAM163 family Cellulase PF00150.13 EEQ75124.1 - 4.6e-15 55.5 0.5 4.6e-15 55.5 0.4 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) EphA2_TM PF14575.1 EEQ75124.1 - 0.02 15.2 0.3 0.14 12.5 0.0 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.20 EEQ75125.1 - 3.8e-60 203.2 0.0 5.2e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ75125.1 - 6.3e-33 113.9 0.0 8.6e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ75125.1 - 1.8e-05 23.8 0.0 2.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEQ75125.1 - 0.0017 18.1 0.2 0.0017 18.1 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ75125.1 - 0.0088 15.1 0.2 0.019 14.0 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF605 PF04652.11 EEQ75125.1 - 2.4 7.4 8.9 3.4 6.9 6.1 1.1 1 0 0 1 1 1 0 Vta1 like SNF2_N PF00176.18 EEQ75127.1 - 2.6e-76 256.2 0.0 4.5e-76 255.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ75127.1 - 9.1e-11 41.4 0.0 2e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD_2 PF06733.10 EEQ75127.1 - 0.03 13.7 0.0 0.03 13.7 0.0 2.1 2 0 0 2 2 2 0 DEAD_2 DZR PF12773.2 EEQ75127.1 - 0.45 10.3 2.7 0.98 9.2 1.9 1.5 1 0 0 1 1 1 0 Double zinc ribbon SIR2 PF02146.12 EEQ75128.1 - 9.3e-38 129.7 0.0 2.4e-36 125.1 0.0 2.1 1 1 0 1 1 1 1 Sir2 family Pyridox_ox_2 PF12900.2 EEQ75129.1 - 1.6e-37 128.5 0.0 2.5e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Peptidase_M24 PF00557.19 EEQ75133.1 - 6.5e-52 176.1 0.0 1.1e-51 175.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EEQ75133.1 - 7.9e-30 102.9 0.0 1.7e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Dfp1_Him1_M PF08630.5 EEQ75134.1 - 1.3e-44 150.9 0.0 4.5e-44 149.2 0.0 1.9 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.7 EEQ75134.1 - 2.6e-23 81.4 0.2 4.9e-23 80.5 0.1 1.5 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.2 EEQ75134.1 - 0.0055 16.5 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EEQ75134.1 - 0.036 14.2 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Pantoate_transf PF02548.10 EEQ75137.1 - 1.9e-103 345.1 0.2 2.2e-103 344.9 0.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EEQ75137.1 - 5.1e-09 35.7 0.6 1.2e-08 34.5 0.4 1.7 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase APG12 PF04110.8 EEQ75138.1 - 5.2e-29 100.2 0.0 8.4e-29 99.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EEQ75138.1 - 0.076 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like Glyco_hydro_16 PF00722.16 EEQ75139.1 - 1.3e-35 122.3 2.6 2e-35 121.7 1.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Acyl-CoA_dh_1 PF00441.19 EEQ75141.1 - 3.7e-33 114.7 0.1 6.8e-33 113.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EEQ75141.1 - 2.7e-20 71.5 1.1 7.1e-20 70.2 0.8 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EEQ75141.1 - 7.7e-20 70.4 0.0 1.7e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EEQ75141.1 - 2.6e-07 31.2 0.2 1.9e-06 28.4 0.0 2.5 2 1 1 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EEQ75141.1 - 4.1e-05 23.8 0.0 0.00011 22.4 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UQ_con PF00179.21 EEQ75145.1 - 3.5e-33 113.9 0.1 4.3e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme LAMTOR PF15454.1 EEQ75146.1 - 1.2e-21 76.6 0.8 4.7e-21 74.8 0.0 2.0 1 1 1 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF4106 PF13388.1 EEQ75146.1 - 0.36 9.7 3.9 0.42 9.5 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF2011 PF09428.5 EEQ75148.1 - 2.2e-43 147.2 6.0 3.5e-43 146.6 4.1 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Cerato-platanin PF07249.7 EEQ75150.1 - 1.7e-42 144.2 0.1 1.9e-42 144.0 0.1 1.0 1 0 0 1 1 1 1 Cerato-platanin Glyco_hydro_45 PF02015.11 EEQ75150.1 - 0.007 16.4 0.1 0.0079 16.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Barwin PF00967.12 EEQ75150.1 - 0.035 13.7 0.0 0.06 13.0 0.0 1.4 2 0 0 2 2 2 0 Barwin family MFS_1 PF07690.11 EEQ75151.1 - 1.4e-45 155.5 43.0 1.4e-45 155.5 29.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ75151.1 - 2.8e-15 55.8 12.1 2.8e-15 55.8 8.4 3.5 3 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EEQ75151.1 - 2.5e-06 25.9 15.4 4.4e-06 25.1 10.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Flavoprotein PF02441.14 EEQ75152.1 - 1.7e-11 43.8 0.1 3.6e-11 42.8 0.1 1.6 1 0 0 1 1 1 1 Flavoprotein Asparaginase_2 PF01112.13 EEQ75153.1 - 7.8e-33 113.5 2.6 1.1e-18 67.0 0.0 4.9 4 2 0 4 4 4 3 Asparaginase Glyco_hydro_98M PF08306.6 EEQ75153.1 - 0.087 11.5 0.0 0.17 10.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 Tim17 PF02466.14 EEQ75154.1 - 5.4e-34 117.0 8.2 6.7e-34 116.7 5.7 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DEAD PF00270.24 EEQ75155.1 - 2e-27 95.7 0.0 3.9e-26 91.5 0.0 2.0 1 1 1 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EEQ75155.1 - 1.6e-22 78.8 0.1 3.1e-22 77.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EEQ75155.1 - 1.5e-20 72.8 0.0 9.3e-20 70.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain NOA36 PF06524.7 EEQ75155.1 - 3.2 6.9 14.5 44 3.2 9.0 2.3 2 0 0 2 2 2 0 NOA36 protein Daxx PF03344.10 EEQ75155.1 - 9.2 4.6 27.2 15 3.8 18.8 1.3 1 0 0 1 1 1 0 Daxx Family DUF2236 PF09995.4 EEQ75156.1 - 1.3e-12 47.5 0.1 2.6e-12 46.5 0.0 1.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) ORMDL PF04061.9 EEQ75158.1 - 2.7e-61 205.0 4.8 3.1e-61 204.8 3.3 1.0 1 0 0 1 1 1 1 ORMDL family Trep_Strep PF09605.5 EEQ75158.1 - 0.44 10.2 4.2 0.4 10.3 1.0 1.9 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) VESA1_N PF12785.2 EEQ75159.1 - 0.2 10.5 14.4 0.32 9.9 10.0 1.3 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 HAD_2 PF13419.1 EEQ75160.1 - 3.3e-14 53.4 0.0 2.6e-12 47.3 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEQ75160.1 - 3.7e-11 43.8 0.0 1.2e-08 35.6 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ75160.1 - 1e-09 37.9 0.0 1.9e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EEQ75160.1 - 2.8e-06 27.6 0.0 4.4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EEQ75160.1 - 0.0068 15.7 0.0 0.041 13.1 0.0 1.9 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.7 EEQ75160.1 - 0.0082 15.7 0.1 0.64 9.5 0.0 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EEQ75160.1 - 0.019 14.3 0.0 0.49 9.7 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Y_phosphatase2 PF03162.8 EEQ75161.1 - 0.13 11.6 0.5 0.24 10.7 0.4 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PRANC PF09372.5 EEQ75162.1 - 0.15 12.0 0.0 0.52 10.3 0.0 1.9 2 0 0 2 2 2 0 PRANC domain Oxidored_FMN PF00724.15 EEQ75164.1 - 6e-93 311.5 0.0 7.2e-93 311.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FeS PF04060.8 EEQ75165.1 - 0.097 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative Fe-S cluster adh_short_C2 PF13561.1 EEQ75166.1 - 3.6e-29 102.2 0.0 4.7e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEQ75166.1 - 3.6e-24 85.5 0.4 4.8e-24 85.1 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ75166.1 - 2.5e-12 46.8 0.2 4.2e-12 46.1 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEQ75166.1 - 0.011 15.1 0.0 0.025 14.0 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family gag_pre-integrs PF13976.1 EEQ75167.1 - 0.053 13.1 0.1 0.073 12.7 0.1 1.3 1 0 0 1 1 1 0 GAG-pre-integrase domain CH PF00307.26 EEQ75168.1 - 8.9e-10 38.5 0.0 2.1e-09 37.3 0.0 1.6 2 0 0 2 2 2 1 Calponin homology (CH) domain NDUFA12 PF05071.11 EEQ75169.1 - 3.7e-13 49.8 1.7 3.7e-13 49.8 1.2 2.1 1 1 1 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 EMP24_GP25L PF01105.19 EEQ75177.1 - 1.2e-42 145.7 0.0 1.3e-42 145.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Sdh5 PF03937.11 EEQ75178.1 - 1.5e-24 85.4 0.2 3.3e-24 84.3 0.1 1.5 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase WD40 PF00400.27 EEQ75179.1 - 2e-60 198.6 26.8 2.8e-12 45.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EEQ75179.1 - 0.00034 18.8 7.7 0.38 8.8 0.2 3.9 2 1 1 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EEQ75179.1 - 0.0044 15.3 0.0 0.31 9.2 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain DUF2683 PF10884.3 EEQ75179.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) PD40 PF07676.7 EEQ75179.1 - 0.13 11.9 0.5 41 3.9 0.0 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat TPR_12 PF13424.1 EEQ75181.1 - 7e-11 41.9 8.2 0.0001 22.1 0.5 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ75181.1 - 2.4e-06 26.9 7.0 0.003 17.2 0.1 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ75181.1 - 0.00071 19.3 1.2 0.00071 19.3 0.8 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ75181.1 - 0.0059 16.2 9.3 0.16 11.5 0.4 3.9 4 0 0 4 4 4 2 TPR repeat TPR_10 PF13374.1 EEQ75181.1 - 0.0068 16.3 5.2 0.38 10.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ75181.1 - 0.0091 15.5 0.8 0.0091 15.5 0.5 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat DUF159 PF02586.9 EEQ75182.1 - 1.5e-54 184.7 0.0 2e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Med1 PF10744.4 EEQ75184.1 - 2e-96 323.1 0.0 2.7e-96 322.7 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Gln-synt_C PF00120.19 EEQ75185.1 - 2.8e-58 197.1 0.0 3.4e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EEQ75185.1 - 8.6e-20 70.1 0.0 1.4e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Sugar_tr PF00083.19 EEQ75186.1 - 3.1e-54 184.2 22.9 3.9e-54 183.9 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ75186.1 - 3.7e-19 68.6 26.8 3.7e-19 68.6 18.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EEQ75186.1 - 0.28 11.0 4.0 0.67 9.7 0.2 3.1 3 0 0 3 3 3 0 MFS_1 like family MFS_1 PF07690.11 EEQ75187.1 - 3e-31 108.4 27.1 3e-31 108.4 18.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EEQ75187.1 - 0.00033 20.1 2.0 0.00061 19.3 1.4 1.4 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 zf-CCHC PF00098.18 EEQ75189.1 - 1.4e-32 110.0 89.1 2.2e-07 30.4 1.4 12.0 12 0 0 12 12 12 9 Zinc knuckle zf-CCHC_3 PF13917.1 EEQ75189.1 - 0.0026 17.4 6.9 0.017 14.8 0.5 8.8 3 3 6 9 9 9 5 Zinc knuckle zf-CCHC_4 PF14392.1 EEQ75189.1 - 0.69 9.6 53.0 0.77 9.4 0.6 9.2 8 1 1 9 9 9 0 Zinc knuckle zf-CCHC_2 PF13696.1 EEQ75189.1 - 3.1 7.3 37.0 1.7 8.1 0.1 8.5 7 2 3 10 10 10 0 Zinc knuckle DUF342 PF03961.8 EEQ75190.1 - 0.063 11.6 2.0 0.087 11.2 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Myb_DNA-bind_6 PF13921.1 EEQ75190.1 - 0.25 11.4 2.5 0.94 9.6 0.0 2.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain IncA PF04156.9 EEQ75190.1 - 1.3 8.6 7.3 2.4 7.7 5.0 1.5 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EEQ75190.1 - 1.8 6.3 4.5 2.5 5.8 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-primase PF09329.6 EEQ75192.1 - 0.025 14.1 0.4 0.048 13.2 0.3 1.5 1 0 0 1 1 1 0 Primase zinc finger Pkinase_Tyr PF07714.12 EEQ75193.1 - 5.7e-20 71.4 0.0 9.9e-09 34.6 0.0 3.9 2 2 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 EEQ75193.1 - 1.8e-14 53.5 0.3 2.1e-10 40.1 0.0 3.4 2 2 1 3 3 3 2 Protein kinase domain YrbL-PhoP_reg PF10707.4 EEQ75193.1 - 0.029 13.7 0.0 0.071 12.4 0.0 1.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Myb_DNA-bind_6 PF13921.1 EEQ75194.1 - 0.0073 16.3 8.7 0.038 14.0 5.7 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Cuticle_2 PF08184.6 EEQ75194.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Cuticle protein 7 isoform family ECH PF00378.15 EEQ75195.1 - 1.7e-42 145.2 0.0 2.1e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EEQ75195.1 - 0.084 12.6 0.0 4.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 Acyl-CoA_dh_1 PF00441.19 EEQ75196.1 - 8.4e-31 107.1 0.0 1.2e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EEQ75196.1 - 2e-21 75.2 0.9 3.4e-21 74.4 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EEQ75196.1 - 7.6e-18 65.1 0.0 1.6e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EEQ75196.1 - 0.0016 18.6 0.0 0.0028 17.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF846 PF05832.7 EEQ75197.1 - 1.2e-49 167.7 9.2 1.4e-49 167.4 6.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Tic20 PF09685.5 EEQ75197.1 - 0.74 9.8 9.1 1.4 8.9 0.7 2.3 2 0 0 2 2 2 0 Tic20-like protein DUF1771 PF08590.5 EEQ75198.1 - 1.5e-15 56.8 12.3 1.5e-15 56.8 8.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EEQ75198.1 - 3e-11 43.3 0.1 1.1e-10 41.5 0.1 2.0 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.19 EEQ75198.1 - 4.9e-08 32.4 1.8 0.0046 16.6 0.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CUE PF02845.11 EEQ75198.1 - 0.004 16.5 0.3 0.064 12.7 0.0 2.7 2 0 0 2 2 2 1 CUE domain HBS1_N PF08938.5 EEQ75198.1 - 0.0056 16.7 0.1 0.03 14.4 0.0 2.1 2 0 0 2 2 2 1 HBS1 N-terminus SNARE_assoc PF09335.6 EEQ75199.1 - 1.4e-10 41.4 5.9 1.4e-10 41.4 4.1 2.6 2 1 1 3 3 3 1 SNARE associated Golgi protein Amino_oxidase PF01593.19 EEQ75200.1 - 9.2e-95 318.3 0.0 1.9e-94 317.2 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 EEQ75200.1 - 1.5e-12 47.4 0.0 3e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 EEQ75200.1 - 3.9e-07 29.9 0.0 9.1e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 EEQ75200.1 - 0.00027 21.1 0.5 0.0048 17.1 0.3 2.4 1 1 0 1 1 1 1 HMG (high mobility group) box DAO PF01266.19 EEQ75200.1 - 0.00061 18.7 0.1 0.011 14.6 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EEQ75200.1 - 0.0021 18.1 0.0 0.29 11.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEQ75200.1 - 0.0053 16.5 0.1 0.18 11.5 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EEQ75200.1 - 0.051 13.4 0.1 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEQ75201.1 - 1e-27 97.3 0.1 1.5e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEQ75201.1 - 2.6e-14 53.3 0.1 2.6e-13 50.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEQ75201.1 - 1.7e-07 31.5 0.0 1.4e-05 25.2 0.0 2.7 2 1 2 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEQ75201.1 - 7.1e-05 22.7 0.0 0.019 15.0 0.0 2.6 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 EEQ75201.1 - 0.00031 20.9 0.1 0.0045 17.2 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding K_oxygenase PF13434.1 EEQ75201.1 - 0.0063 15.4 0.0 0.057 12.3 0.0 2.3 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EEQ75201.1 - 0.0085 15.0 0.0 6.2 5.6 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEQ75201.1 - 0.033 13.0 2.7 4.8 5.9 0.1 2.9 2 1 0 3 3 3 0 FAD binding domain GIDA PF01134.17 EEQ75201.1 - 0.055 12.3 0.1 8.6 5.0 0.0 2.9 3 1 0 3 3 3 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 EEQ75201.1 - 0.12 12.5 0.0 5.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Peptidase_S8 PF00082.17 EEQ75204.1 - 6.2e-55 186.3 2.6 8.8e-55 185.8 1.8 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 EEQ75204.1 - 1.3e-22 79.3 0.5 2.4e-22 78.5 0.4 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain PX PF00787.19 EEQ75206.1 - 3e-18 65.6 0.1 6.2e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EEQ75206.1 - 2.1e-14 53.3 8.6 2.5e-07 30.1 0.4 2.1 2 0 0 2 2 2 2 Vps5 C terminal like IncA PF04156.9 EEQ75206.1 - 0.2 11.2 3.4 0.96 9.0 0.0 2.2 2 0 0 2 2 2 0 IncA protein BAR PF03114.13 EEQ75206.1 - 0.27 10.6 7.4 5 6.5 5.1 2.3 1 1 0 1 1 1 0 BAR domain DUF1664 PF07889.7 EEQ75206.1 - 0.3 10.8 2.5 6 6.6 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.15 EEQ75206.1 - 0.36 10.6 5.9 0.66 9.7 0.3 2.3 2 0 0 2 2 2 0 Prefoldin subunit Laminin_II PF06009.7 EEQ75206.1 - 0.36 10.5 2.6 0.23 11.2 0.3 1.8 2 1 0 2 2 2 0 Laminin Domain II PilJ PF13675.1 EEQ75206.1 - 0.59 10.4 3.0 2.9 8.2 0.1 2.8 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF724 PF05266.9 EEQ75206.1 - 0.89 9.1 4.3 18 4.8 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.14 EEQ75206.1 - 3.5 5.3 4.7 9.9 3.8 0.3 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 EEQ75206.1 - 4.3 6.8 5.9 11 5.5 0.2 2.7 3 0 0 3 3 3 0 Septum formation initiator Mucin PF01456.12 EEQ75207.1 - 0.022 14.5 38.7 0.041 13.6 26.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 EEQ75207.1 - 0.049 11.6 22.9 0.065 11.2 15.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 IER PF05760.7 EEQ75207.1 - 0.2 11.5 4.4 0.25 11.2 3.1 1.3 1 0 0 1 1 1 0 Immediate early response protein (IER) KIAA1328 PF15369.1 EEQ75207.1 - 0.54 10.0 3.4 0.55 9.9 2.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Dicty_REP PF05086.7 EEQ75207.1 - 0.62 7.7 15.5 0.94 7.1 10.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DNA_pol_viral_N PF00242.12 EEQ75207.1 - 1.4 7.8 8.1 1.8 7.5 5.6 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain FAM163 PF15069.1 EEQ75207.1 - 3.8 8.0 10.0 11 6.6 0.0 2.1 2 0 0 2 2 2 0 FAM163 family FAD_binding_3 PF01494.14 EEQ75209.1 - 1.2e-19 70.5 0.0 2.5e-12 46.5 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 EEQ75209.1 - 0.0032 17.2 0.0 0.0069 16.1 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EEQ75209.1 - 0.0051 15.7 0.0 0.0092 14.9 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein K_oxygenase PF13434.1 EEQ75209.1 - 0.0092 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) SE PF08491.5 EEQ75209.1 - 0.016 14.0 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_3 PF13738.1 EEQ75209.1 - 0.031 14.3 0.0 0.48 10.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EEQ75209.1 - 0.077 11.6 0.0 0.24 10.0 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 EEQ75209.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase tRNA-synt_His PF13393.1 EEQ75210.1 - 5.8e-39 133.9 0.1 2e-32 112.4 0.0 2.7 3 0 0 3 3 3 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EEQ75210.1 - 2.1e-18 66.4 0.0 4.7e-18 65.3 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEQ75210.1 - 1.7e-12 47.1 0.0 5.3e-12 45.5 0.0 1.9 1 1 1 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EEQ75210.1 - 8.8e-05 21.4 0.0 0.0074 15.0 0.0 2.7 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) Ribosomal_60s PF00428.14 EEQ75210.1 - 0.0043 17.4 6.6 0.4 11.1 0.1 2.6 2 0 0 2 2 2 2 60s Acidic ribosomal protein DUF937 PF06078.6 EEQ75210.1 - 0.11 12.7 0.1 0.24 11.6 0.0 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF937) DUF1795 PF08786.6 EEQ75210.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1795) UCH PF00443.24 EEQ75211.1 - 6.2e-60 202.5 0.1 6.2e-60 202.5 0.1 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEQ75211.1 - 5.9e-30 104.7 1.6 1.4e-22 80.5 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EEQ75211.1 - 0.025 13.8 4.3 0.18 11.0 2.0 2.5 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Yos1 PF08571.5 EEQ75212.1 - 6.6e-31 106.2 0.6 8.7e-31 105.8 0.4 1.2 1 0 0 1 1 1 1 Yos1-like Glyco_transf_22 PF03901.12 EEQ75213.1 - 2.7e-07 29.9 0.9 3.8e-07 29.4 0.5 1.3 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family Dynamitin PF04912.9 EEQ75214.1 - 9.1e-19 67.5 0.0 2.8e-13 49.4 0.0 2.3 2 1 0 2 2 2 2 Dynamitin DivIC PF04977.10 EEQ75214.1 - 0.0015 17.9 9.4 0.049 13.1 0.1 3.4 3 0 0 3 3 3 1 Septum formation initiator ADIP PF11559.3 EEQ75214.1 - 0.0019 18.1 2.7 4.6 7.1 1.1 3.2 3 0 0 3 3 3 2 Afadin- and alpha -actinin-Binding IncA PF04156.9 EEQ75214.1 - 0.01 15.4 3.4 0.82 9.2 0.1 2.8 3 0 0 3 3 3 0 IncA protein DUF3166 PF11365.3 EEQ75214.1 - 0.031 14.7 0.8 0.031 14.7 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) GAS PF13851.1 EEQ75214.1 - 0.17 11.0 2.9 0.44 9.7 0.8 2.3 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Spc24 PF08286.6 EEQ75214.1 - 0.33 10.6 3.1 2 8.1 1.0 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Viral_P18 PF04521.8 EEQ75214.1 - 0.64 9.4 6.0 11 5.5 0.1 3.1 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein GrpE PF01025.14 EEQ75214.1 - 1.1 8.8 4.6 0.63 9.5 0.3 2.3 3 0 0 3 3 3 0 GrpE CorA PF01544.13 EEQ75214.1 - 2.3 7.1 6.0 5.1 6.0 2.2 2.4 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Mnd1 PF03962.10 EEQ75214.1 - 3.5 7.2 5.9 2.1 7.9 1.1 2.3 3 0 0 3 3 3 0 Mnd1 family APG6 PF04111.7 EEQ75214.1 - 3.8 6.4 6.5 10 5.0 1.5 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 Aldedh PF00171.17 EEQ75218.1 - 1.1e-134 449.2 0.2 1.3e-134 449.0 0.2 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EEQ75218.1 - 0.0044 15.8 0.0 0.0067 15.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) GTP_cyclohydro2 PF00925.15 EEQ75218.1 - 0.13 11.4 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase II Calreticulin PF00262.13 EEQ75219.1 - 2.2e-165 549.7 24.7 1.3e-164 547.1 12.3 2.0 2 0 0 2 2 2 2 Calreticulin family Aldolase_II PF00596.16 EEQ75220.1 - 1.1e-41 142.4 0.0 1.3e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Vps5 PF09325.5 EEQ75221.1 - 9.9e-87 290.0 4.9 9.9e-87 290.0 3.4 1.3 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 EEQ75221.1 - 5e-25 87.5 0.0 1.4e-24 86.0 0.0 1.8 1 0 0 1 1 1 1 PX domain His_Phos_2 PF00328.17 EEQ75221.1 - 0.013 14.8 4.1 0.025 13.8 2.6 1.6 1 1 1 2 2 2 0 Histidine phosphatase superfamily (branch 2) MCP_N PF05581.7 EEQ75221.1 - 0.022 14.9 0.0 10 6.3 0.0 2.3 2 0 0 2 2 2 0 Vibrio chemotaxis protein N terminus DUF3450 PF11932.3 EEQ75222.1 - 0.11 11.6 1.6 5.2 6.2 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Ribosomal_L31 PF01197.13 EEQ75222.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L31 Phyto_Pns9_10 PF05878.6 EEQ75222.1 - 0.28 10.1 2.0 0.35 9.8 1.4 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 MSP1_C PF07462.6 EEQ75222.1 - 0.31 9.3 2.6 0.39 9.0 1.8 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Flavin_Reduct PF01613.13 EEQ75223.1 - 2.4e-26 92.4 0.7 6e-26 91.1 0.5 1.6 1 1 0 1 1 1 1 Flavin reductase like domain 4HBT_2 PF13279.1 EEQ75225.1 - 8.2e-23 81.1 0.0 1.5e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EEQ75225.1 - 0.0034 17.4 0.0 0.009 16.1 0.0 1.7 1 0 0 1 1 1 1 Thioesterase superfamily Complex1_LYR_2 PF13233.1 EEQ75229.1 - 1.2e-06 28.9 0.0 1.5e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Methyltransf_11 PF08241.7 EEQ75230.1 - 3.4e-06 27.4 0.0 7.6e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ75230.1 - 4e-06 27.1 0.0 7.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ75230.1 - 0.00024 20.8 0.0 0.00064 19.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ75230.1 - 0.0029 16.7 0.0 0.0048 16.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EEQ75230.1 - 0.0076 15.8 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ75230.1 - 0.025 14.6 0.0 0.065 13.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ75230.1 - 0.068 13.7 0.0 0.2 12.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain WD40 PF00400.27 EEQ75232.1 - 3.6e-12 45.6 3.7 0.00064 19.5 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat NACHT PF05729.7 EEQ75232.1 - 5.1e-07 29.5 1.9 8e-06 25.6 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA PF00004.24 EEQ75232.1 - 0.01 16.0 0.3 0.37 11.0 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 EEQ75232.1 - 0.14 11.8 0.3 0.39 10.3 0.1 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase Exo_endo_phos PF03372.18 EEQ75233.1 - 4.8e-22 79.0 0.1 8.3e-22 78.3 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.1 EEQ75233.1 - 1.1e-16 60.2 22.1 2.2e-08 33.7 4.0 2.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EEQ75233.1 - 7.2e-16 57.4 7.8 4e-11 42.2 0.6 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EEQ75233.1 - 2.9e-07 29.5 5.8 0.029 14.3 0.0 4.3 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 EEQ75233.1 - 8.5e-06 25.1 11.4 0.069 13.3 0.0 4.2 4 0 0 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 EEQ75233.1 - 1.2 9.4 0.0 1.2 9.4 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich repeat MFS_1 PF07690.11 EEQ75235.1 - 9.5e-46 156.1 50.5 9.5e-46 156.1 35.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ75235.1 - 3.4e-24 84.9 18.3 5.8e-24 84.2 12.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEQ75235.1 - 2.9e-14 52.5 16.4 2.9e-14 52.5 11.4 3.9 2 1 2 4 4 4 1 Sugar (and other) transporter DUF1348 PF07080.6 EEQ75236.1 - 1e-40 138.8 2.0 1.2e-40 138.6 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 EEQ75236.1 - 9.8e-06 25.9 0.2 1.3e-05 25.5 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EEQ75236.1 - 3.9e-05 23.8 0.1 5.3e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) zf-CCHC_3 PF13917.1 EEQ75236.1 - 0.12 12.1 0.3 0.22 11.2 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Hydrolase_4 PF12146.3 EEQ75237.1 - 7.2e-18 64.2 0.0 5.6e-17 61.3 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 EEQ75237.1 - 7.9e-15 55.3 0.0 1.1e-14 54.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ75237.1 - 9.1e-15 54.6 0.0 1.4e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EEQ75237.1 - 5.4e-08 32.5 0.0 0.009 15.4 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DUF1749 PF08538.5 EEQ75237.1 - 0.0084 15.0 0.0 0.03 13.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Peptidase_S9 PF00326.16 EEQ75237.1 - 0.018 14.2 0.0 0.44 9.7 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Chlorophyllase PF07224.6 EEQ75237.1 - 0.031 13.0 0.0 3.1 6.4 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase DLH PF01738.13 EEQ75237.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family GCD14 PF08704.5 EEQ75238.1 - 7.4e-07 28.9 0.8 0.0013 18.2 0.0 2.8 3 0 0 3 3 3 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 EEQ75238.1 - 0.086 13.4 0.0 2.3 8.8 0.0 2.7 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ75238.1 - 0.13 11.8 0.0 3.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Di19_C PF14571.1 EEQ75238.1 - 0.37 11.1 0.0 0.37 11.1 0.0 3.1 3 0 0 3 3 3 0 Stress-induced protein Di19, C-terminal Pap_E4 PF02711.9 EEQ75238.1 - 9.5 7.1 7.7 1.2 9.9 1.1 2.4 2 0 0 2 2 2 0 E4 protein Metallophos PF00149.23 EEQ75239.1 - 9.9e-11 41.4 0.0 5.4e-10 39.0 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEQ75239.1 - 3.6e-05 23.6 0.0 8.4e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NAD_binding_6 PF08030.7 EEQ75240.1 - 2e-05 24.5 0.0 0.00049 20.0 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EEQ75240.1 - 3.9e-05 24.1 0.0 0.072 13.6 0.0 2.9 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain MARVEL PF01284.18 EEQ75241.1 - 4.6e-05 23.2 1.7 8.8e-05 22.3 1.2 1.5 1 1 0 1 1 1 1 Membrane-associating domain DUF605 PF04652.11 EEQ75241.1 - 1.2 8.4 5.8 1.3 8.3 4.0 1.2 1 0 0 1 1 1 0 Vta1 like E1-E2_ATPase PF00122.15 EEQ75242.1 - 3e-52 176.9 0.2 7.5e-52 175.6 0.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EEQ75242.1 - 1.6e-45 156.1 0.8 2.8e-45 155.3 0.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EEQ75242.1 - 2.3e-40 136.5 1.5 5.3e-12 45.7 0.1 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 EEQ75242.1 - 2.4e-14 53.9 0.0 1.3e-13 51.5 0.0 2.3 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEQ75242.1 - 0.0026 17.3 0.6 0.0091 15.5 0.3 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase GFA PF04828.9 EEQ75242.1 - 0.016 15.1 0.3 8.1 6.4 0.0 3.1 3 0 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Hydrolase_6 PF13344.1 EEQ75242.1 - 0.12 12.2 0.0 22 4.9 0.0 3.7 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase PCI PF01399.22 EEQ75244.1 - 3.4e-06 27.3 0.0 5.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 PCI domain NnrS PF05940.7 EEQ75244.1 - 0.034 13.0 0.0 0.048 12.5 0.0 1.1 1 0 0 1 1 1 0 NnrS protein RGS PF00615.14 EEQ75245.1 - 3.1e-12 46.6 0.0 1.7e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain PrgI PF12666.2 EEQ75245.1 - 7.7 6.7 7.3 1.6 8.9 0.7 2.2 1 1 0 2 2 2 0 PrgI family protein Bromodomain PF00439.20 EEQ75246.1 - 3.6e-26 90.8 1.1 7e-26 89.9 0.8 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EEQ75246.1 - 5.2e-10 39.3 0.1 1.6e-09 37.7 0.1 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEQ75246.1 - 1e-08 35.0 0.1 2.8e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Rad1 PF02144.11 EEQ75247.1 - 1.6e-95 319.0 0.0 1.9e-95 318.8 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 AAA_23 PF13476.1 EEQ75248.1 - 2.6e-27 96.4 1.7 2.6e-27 96.4 1.2 7.8 2 1 2 5 5 5 1 AAA domain SbcCD_C PF13558.1 EEQ75248.1 - 8.7e-12 44.8 0.0 3e-11 43.0 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 EEQ75248.1 - 8.2e-09 34.4 123.4 0.00038 19.0 16.6 6.8 2 1 5 7 7 7 5 AAA domain SMC_N PF02463.14 EEQ75248.1 - 4.9e-06 25.9 0.0 4.9e-06 25.9 0.0 4.1 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEQ75248.1 - 6.1e-06 26.4 13.0 0.0013 18.7 0.0 4.2 5 1 0 5 5 5 2 AAA domain AAA_29 PF13555.1 EEQ75248.1 - 0.00082 18.8 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF948 PF06103.6 EEQ75248.1 - 0.0044 16.8 0.7 0.0044 16.8 0.5 7.9 8 1 0 8 8 8 2 Bacterial protein of unknown function (DUF948) MobB PF03205.9 EEQ75248.1 - 0.0072 16.0 1.4 0.031 13.9 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B PPE PF00823.14 EEQ75248.1 - 0.12 12.1 1.5 2.9 7.7 0.0 3.0 2 0 0 2 2 2 0 PPE family Reo_sigmaC PF04582.7 EEQ75248.1 - 6.9 5.7 39.8 0.4 9.8 1.5 6.2 3 2 3 7 7 7 0 Reovirus sigma C capsid protein PAS_3 PF08447.6 EEQ75249.1 - 2.3e-12 46.8 0.0 9.7e-12 44.8 0.0 1.9 2 0 0 2 2 2 1 PAS fold GATA PF00320.22 EEQ75249.1 - 1.2e-11 43.7 5.8 3.2e-11 42.3 4.0 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS_9 PF13426.1 EEQ75249.1 - 1.1e-07 32.1 0.0 2.8e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.1 EEQ75249.1 - 1.3e-07 31.5 0.0 2.3e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EEQ75249.1 - 2.5e-07 30.4 0.0 5.1e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 PAS fold PPP4R2 PF09184.6 EEQ75250.1 - 3.1e-08 33.5 4.2 7.6e-08 32.2 0.0 2.9 3 0 0 3 3 3 1 PPP4R2 SUFU PF05076.8 EEQ75251.1 - 0.0002 21.0 0.0 0.0005 19.6 0.0 1.6 2 0 0 2 2 2 1 Suppressor of fused protein (SUFU) Tfb2 PF03849.9 EEQ75251.1 - 0.094 11.3 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Transcription factor Tfb2 DUF155 PF02582.9 EEQ75256.1 - 3.6e-58 196.3 0.0 5.4e-58 195.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 AMP-binding PF00501.23 EEQ75257.1 - 4.3e-18 64.8 0.0 5.6e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Iron_permease PF04120.7 EEQ75258.1 - 0.039 13.5 2.4 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Low affinity iron permease DUF4557 PF15101.1 EEQ75258.1 - 0.15 11.8 9.1 0.19 11.5 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Rtf2 PF04641.7 EEQ75258.1 - 1.7 7.7 16.8 2.3 7.3 11.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger RR_TM4-6 PF06459.7 EEQ75258.1 - 2.6 7.8 9.0 3.8 7.3 6.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FimP PF09766.4 EEQ75258.1 - 3.1 6.7 15.2 5 6.0 10.5 1.2 1 0 0 1 1 1 0 Fms-interacting protein DDHD PF02862.12 EEQ75258.1 - 3.6 7.3 9.1 5.1 6.8 6.3 1.2 1 0 0 1 1 1 0 DDHD domain Suf PF05843.9 EEQ75258.1 - 7.3 6.2 11.4 9.9 5.7 7.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hid1 PF12722.2 EEQ75258.1 - 9.9 3.6 10.7 12 3.4 7.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-H2C2_2 PF13465.1 EEQ75259.1 - 5.8e-21 73.6 25.2 2.9e-07 30.4 0.9 5.4 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 EEQ75259.1 - 8.3e-19 66.7 32.2 4.1e-05 23.6 1.2 4.7 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ75259.1 - 4e-11 42.4 30.9 0.00047 20.2 3.1 4.7 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEQ75259.1 - 0.0011 19.0 12.8 0.77 9.9 0.0 4.9 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EEQ75259.1 - 0.0044 16.8 17.0 1.1 9.2 0.2 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger YjzC PF14168.1 EEQ75259.1 - 0.024 14.5 0.1 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 YjzC-like protein XPA_N PF01286.13 EEQ75259.1 - 0.12 12.1 0.4 0.12 12.1 0.3 3.0 4 0 0 4 4 4 0 XPA protein N-terminal zf-met PF12874.2 EEQ75259.1 - 0.3 11.3 0.1 0.3 11.3 0.1 4.7 5 0 0 5 5 5 0 Zinc-finger of C2H2 type C1_1 PF00130.17 EEQ75259.1 - 0.32 10.7 6.0 0.51 10.1 0.7 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.5 EEQ75259.1 - 0.61 10.0 11.3 31 4.6 1.2 3.7 2 1 2 4 4 4 0 Zinc ribbon domain zf-C2HC_2 PF13913.1 EEQ75259.1 - 3.3 7.4 10.1 2.3 7.9 0.4 3.7 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Methyltransf_23 PF13489.1 EEQ75260.1 - 4.3e-17 62.3 0.0 6.4e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ75260.1 - 3.1e-10 40.4 0.0 0.0008 19.8 0.0 3.2 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ75260.1 - 4.9e-10 39.7 0.0 1.1e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ75260.1 - 4.1e-08 33.7 0.0 1.1e-06 29.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ75260.1 - 3.2e-06 27.1 0.0 6.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ75260.1 - 5.5e-06 26.0 0.0 0.018 14.6 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ75260.1 - 0.00022 21.5 0.0 0.00037 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Prp18 PF02840.10 EEQ75260.1 - 0.11 12.2 0.1 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Prp18 domain CMAS PF02353.15 EEQ75260.1 - 0.12 11.4 0.0 3.6 6.6 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Peptidase_M6 PF05547.6 EEQ75261.1 - 1e-05 23.8 0.2 0.0042 15.2 0.2 2.1 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 Peptidase_M90 PF06167.7 EEQ75261.1 - 0.055 12.8 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 E1-E2_ATPase PF00122.15 EEQ75262.1 - 2.7e-67 226.1 2.5 4.2e-67 225.5 1.7 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEQ75262.1 - 1.6e-35 122.3 1.1 1.6e-35 122.3 0.8 2.4 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEQ75262.1 - 2.9e-24 86.6 0.0 2.1e-23 83.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ75262.1 - 9e-23 80.0 0.0 2e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EEQ75262.1 - 7.8e-10 39.2 0.0 2.5e-09 37.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEQ75262.1 - 2.2e-05 24.1 1.9 0.0019 17.8 1.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEQ75263.1 - 2.2e-12 46.2 0.0 3e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus BRAP2 PF07576.7 EEQ75264.1 - 7.4e-26 89.8 0.0 1.6e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EEQ75264.1 - 3.1e-20 72.0 3.8 8.6e-20 70.6 2.6 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein TPR_MLP1_2 PF07926.7 EEQ75264.1 - 0.036 13.8 11.8 0.074 12.7 8.2 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein FadA PF09403.5 EEQ75264.1 - 0.39 10.7 7.7 0.56 10.2 4.8 1.6 1 1 0 1 1 1 0 Adhesion protein FadA DUF4200 PF13863.1 EEQ75264.1 - 4.3 7.2 10.9 8.5 6.3 2.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) ubiquitin PF00240.18 EEQ75265.1 - 4.3e-168 545.0 30.4 1.6e-33 113.9 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.3 EEQ75265.1 - 1.7e-96 315.9 27.8 6.2e-19 67.4 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EEQ75265.1 - 2.1e-29 101.5 14.7 0.00021 21.4 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EEQ75265.1 - 1.6e-26 92.8 2.4 0.001 18.7 0.0 5.0 5 0 0 5 5 5 5 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EEQ75265.1 - 1e-16 60.7 4.2 0.17 11.7 0.0 5.9 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EEQ75265.1 - 1.9e-16 60.0 3.9 0.18 12.0 0.0 5.2 1 1 4 5 5 5 5 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EEQ75265.1 - 2.6e-13 49.8 0.0 2 8.4 0.0 5.8 5 0 0 5 5 5 5 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.9 EEQ75265.1 - 8.2e-08 31.6 1.4 2.8 7.0 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase TUG-UBL1 PF11470.3 EEQ75265.1 - 6.8e-07 29.1 8.2 6.3 6.7 0.0 5.2 5 0 0 5 5 5 4 GLUT4 regulating protein TUG FlgD_ig PF13860.1 EEQ75265.1 - 0.00017 21.2 8.4 19 5.1 0.0 5.2 5 0 0 5 5 5 0 FlgD Ig-like domain Plexin_cytopl PF08337.7 EEQ75265.1 - 0.0011 17.4 18.2 3.1 5.9 0.2 6.6 6 4 0 6 6 6 4 Plexin cytoplasmic RasGAP domain Big_3_3 PF13750.1 EEQ75265.1 - 0.002 17.5 0.1 58 3.0 0.0 4.2 4 1 0 4 4 4 0 Bacterial Ig-like domain (group 3) ACT_4 PF13291.1 EEQ75265.1 - 0.0028 17.9 0.9 1.4e+02 2.9 0.0 4.7 5 0 0 5 5 5 0 ACT domain CTDII PF01556.13 EEQ75265.1 - 0.017 15.0 19.3 11 6.0 0.2 5.3 1 1 4 5 5 5 0 DnaJ C terminal domain Tash_PEST PF07708.6 EEQ75265.1 - 0.036 13.9 34.4 4.5 7.3 1.2 5.3 5 0 0 5 5 5 0 Tash protein PEST motif GABP-alpha PF11620.3 EEQ75265.1 - 0.1 12.5 11.4 63 3.6 0.1 4.9 5 0 0 5 5 5 0 GA-binding protein alpha chain FERM_N PF09379.5 EEQ75265.1 - 0.79 9.8 16.5 58 3.8 0.1 6.8 5 5 0 5 5 5 0 FERM N-terminal domain DUF3781 PF12636.2 EEQ75265.1 - 1.2 9.1 9.4 1.3e+02 2.5 0.1 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF3781) Trypan_PARP PF05887.6 EEQ75267.1 - 0.00012 21.9 8.1 0.00012 21.9 5.6 1.7 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) BCLP PF12304.3 EEQ75267.1 - 0.13 11.6 0.4 0.17 11.3 0.3 1.1 1 0 0 1 1 1 0 Beta-casein like protein PLRV_ORF5 PF01690.12 EEQ75267.1 - 3.6 6.6 20.8 4.7 6.2 14.4 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Zn_clus PF00172.13 EEQ75268.1 - 0.0021 17.8 7.7 0.006 16.4 5.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SelP_N PF04592.9 EEQ75268.1 - 3.3 7.0 21.5 8.7 5.6 14.9 1.7 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Prenyltrans PF00432.16 EEQ75272.1 - 1.1e-30 104.8 19.4 3.4e-10 39.3 0.7 5.2 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EEQ75272.1 - 3.1e-21 75.8 0.0 1.3e-15 57.7 0.0 3.6 1 1 2 3 3 3 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 EEQ75272.1 - 0.00022 21.2 0.0 0.0027 17.7 0.0 2.5 3 0 0 3 3 3 1 Prenyltransferase-like SR-25 PF10500.4 EEQ75272.1 - 0.91 8.9 14.5 1.6 8.1 10.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rrn6 PF10214.4 EEQ75272.1 - 7.7 4.4 13.9 10 4.0 9.6 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor dsrm PF00035.20 EEQ75273.1 - 0.0026 18.2 0.0 0.005 17.3 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif TFIIF_alpha PF05793.7 EEQ75275.1 - 0.24 9.7 2.4 0.31 9.3 1.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4448 PF14610.1 EEQ75279.1 - 7.9e-46 155.9 0.0 1.3e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) HMGL-like PF00682.14 EEQ75280.1 - 1.2e-71 241.1 0.6 1.8e-71 240.5 0.4 1.3 1 0 0 1 1 1 1 HMGL-like Pkinase PF00069.20 EEQ75281.1 - 3.2e-21 75.6 0.0 4e-21 75.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ75281.1 - 6.8e-15 54.8 0.0 9e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ75281.1 - 5.4e-06 25.5 0.0 7e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEQ75281.1 - 0.0057 16.4 0.0 0.027 14.2 0.0 1.7 1 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EEQ75281.1 - 0.0065 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EEQ75281.1 - 0.0076 15.3 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Hpt PF01627.18 EEQ75282.1 - 1e-11 44.6 0.0 1.8e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Hpt domain DUF3235 PF11574.3 EEQ75283.1 - 0.045 13.9 3.5 0.057 13.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) PTH2 PF01981.11 EEQ75284.1 - 2.3e-41 140.1 0.0 3.4e-41 139.5 0.0 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Trypan_PARP PF05887.6 EEQ75284.1 - 0.26 11.1 4.9 0.42 10.4 3.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SART-1 PF03343.8 EEQ75285.1 - 1.4e-174 581.8 69.9 1.7e-174 581.6 48.5 1.0 1 0 0 1 1 1 1 SART-1 family Aminotran_1_2 PF00155.16 EEQ75286.1 - 1.2e-94 317.2 0.0 1.4e-94 317.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Lipase_3 PF01764.20 EEQ75287.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Lipase (class 3) Pyridoxal_deC PF00282.14 EEQ75288.1 - 3.7e-19 68.4 0.0 5.7e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EEQ75288.1 - 3.4e-05 22.7 0.0 0.00015 20.6 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EEQ75288.1 - 6.6e-05 22.1 0.0 0.00011 21.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EEQ75288.1 - 9e-05 21.5 0.0 0.00017 20.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EEQ75288.1 - 0.0076 14.5 0.0 0.012 13.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF1775 PF07987.6 EEQ75288.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unkown function (DUF1775) Resolvase PF00239.16 EEQ75288.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Resolvase, N terminal domain Ribosomal_L30 PF00327.15 EEQ75289.1 - 1.7e-15 56.2 0.1 2.5e-15 55.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Sec6 PF06046.8 EEQ75290.1 - 3.5e-174 580.0 11.2 3.5e-174 580.0 7.7 1.4 2 0 0 2 2 2 1 Exocyst complex component Sec6 Vps53_N PF04100.7 EEQ75290.1 - 0.15 10.8 9.0 0.12 11.0 0.6 2.7 3 0 0 3 3 3 0 Vps53-like, N-terminal DUF4654 PF15547.1 EEQ75290.1 - 3.8 7.8 10.5 4.7 7.5 6.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4654) DUF1311 PF07007.7 EEQ75290.1 - 4.1 7.5 7.6 14 5.8 0.8 3.6 2 2 2 4 4 4 0 Protein of unknown function (DUF1311) AKAP7_NLS PF10469.4 EEQ75291.1 - 1.9e-16 60.4 0.0 3.4e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Frataxin_Cyay PF01491.11 EEQ75292.1 - 2.6e-32 110.8 0.0 3.6e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain SOG2 PF10428.4 EEQ75292.1 - 0.4 9.2 3.3 0.53 8.8 2.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein zf-CSL PF05207.8 EEQ75293.1 - 2.1e-23 81.5 0.4 2.5e-23 81.3 0.3 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 EEQ75293.1 - 0.014 15.3 0.2 0.026 14.4 0.1 1.4 1 0 0 1 1 1 0 Zinc ribbon domain HAUS4 PF14735.1 EEQ75294.1 - 0.00079 18.8 2.5 0.0027 17.0 0.7 2.4 2 1 0 2 2 2 1 HAUS augmin-like complex subunit 4 DinB_2 PF12867.2 EEQ75294.1 - 0.18 12.1 3.1 0.37 11.1 0.7 2.5 2 1 0 2 2 2 0 DinB superfamily PH_6 PF15406.1 EEQ75295.1 - 1.4e-36 124.9 2.1 1.4e-36 124.9 1.5 4.0 3 1 2 5 5 5 1 Pleckstrin homology domain PH PF00169.24 EEQ75295.1 - 5.1e-05 23.4 0.0 0.00018 21.6 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_4 PF15404.1 EEQ75295.1 - 0.51 9.8 0.0 0.51 9.8 0.0 4.1 3 2 1 4 4 4 0 Pleckstrin homology domain PNTB PF02233.11 EEQ75296.1 - 8.1e-173 575.4 23.2 8.1e-173 575.4 16.1 1.7 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EEQ75296.1 - 2.5e-50 170.3 0.2 4.7e-50 169.4 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EEQ75296.1 - 5.6e-42 142.9 0.0 1.5e-41 141.5 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EEQ75296.1 - 3.1e-30 104.1 4.5 3.1e-30 104.1 3.1 4.9 4 2 1 5 5 5 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 EEQ75296.1 - 0.0048 16.0 4.2 1.4 8.0 0.0 3.8 3 1 0 4 4 4 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_31 PF13847.1 EEQ75296.1 - 0.054 13.0 0.0 0.26 10.8 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain TPP_enzyme_M PF00205.17 EEQ75296.1 - 0.057 13.1 1.3 0.97 9.1 0.2 3.3 3 1 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain Pyr_redox_2 PF07992.9 EEQ75296.1 - 0.32 10.8 1.5 0.42 10.4 0.3 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EEQ75296.1 - 8.4 6.5 6.7 8.2 6.5 0.0 3.2 3 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase bZIP_1 PF00170.16 EEQ75298.1 - 1.3e-08 34.6 6.1 2e-08 34.0 4.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEQ75298.1 - 6.2e-06 25.9 9.4 1e-05 25.2 6.5 1.3 1 0 0 1 1 1 1 Basic region leucine zipper RRM_3 PF08777.6 EEQ75298.1 - 0.071 12.9 0.3 0.1 12.4 0.2 1.2 1 0 0 1 1 1 0 RNA binding motif Lipase_GDSL_2 PF13472.1 EEQ75299.1 - 1.1e-15 58.2 0.0 2.4e-15 57.1 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EEQ75299.1 - 0.0032 17.3 0.0 0.011 15.6 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DIOX_N PF14226.1 EEQ75300.1 - 3.7e-27 95.1 0.0 6.5e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EEQ75300.1 - 1.2e-19 70.4 0.0 2.1e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily F-box-like PF12937.2 EEQ75301.1 - 0.00011 21.8 0.0 0.00036 20.1 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EEQ75301.1 - 0.00012 21.6 0.1 0.00087 18.8 0.0 2.2 2 0 0 2 2 2 1 F-box domain Mito_carr PF00153.22 EEQ75303.1 - 4e-59 196.3 1.4 3.1e-20 71.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Prefoldin_2 PF01920.15 EEQ75306.1 - 6.3e-18 64.4 5.0 7.7e-18 64.2 3.5 1.2 1 0 0 1 1 1 1 Prefoldin subunit Pox_A_type_inc PF04508.7 EEQ75306.1 - 0.0037 16.9 0.9 0.26 11.1 0.1 3.0 2 1 1 3 3 3 1 Viral A-type inclusion protein repeat BLOC1_2 PF10046.4 EEQ75306.1 - 0.0038 17.3 3.3 0.019 15.1 0.1 2.3 2 1 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lectin_N PF03954.9 EEQ75306.1 - 0.036 13.4 0.7 0.059 12.7 0.4 1.5 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain TPR_MLP1_2 PF07926.7 EEQ75306.1 - 0.054 13.2 2.5 0.08 12.6 1.7 1.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Syntaxin PF00804.20 EEQ75306.1 - 0.079 13.1 4.5 0.33 11.1 3.1 1.8 1 1 0 1 1 1 0 Syntaxin Fib_alpha PF08702.5 EEQ75306.1 - 0.17 11.9 6.3 0.73 9.9 0.4 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family YjcZ PF13990.1 EEQ75306.1 - 0.17 10.9 2.7 0.54 9.3 1.9 1.6 1 1 0 1 1 1 0 YjcZ-like protein Jnk-SapK_ap_N PF09744.4 EEQ75306.1 - 0.33 10.9 2.9 0.71 9.8 1.8 1.7 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Spc24 PF08286.6 EEQ75306.1 - 0.77 9.4 6.4 2.2 8.0 0.4 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Fzo_mitofusin PF04799.8 EEQ75306.1 - 1 8.6 4.4 0.75 9.1 0.3 2.0 1 1 1 2 2 2 0 fzo-like conserved region IncA PF04156.9 EEQ75306.1 - 1.4 8.4 6.0 3.5 7.1 0.2 2.0 1 1 0 1 1 1 0 IncA protein FlxA PF14282.1 EEQ75306.1 - 8.8 6.3 12.0 24 4.9 4.7 2.4 2 1 0 2 2 2 0 FlxA-like protein DUF3435 PF11917.3 EEQ75307.1 - 4.3e-129 430.8 2.3 4.5e-129 430.8 0.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) Phage_int_SAM_4 PF13495.1 EEQ75307.1 - 0.51 10.7 6.7 0.93 9.8 0.0 3.9 4 1 1 5 5 5 0 Phage integrase, N-terminal SAM-like domain APH PF01636.18 EEQ75308.1 - 2.6e-07 30.6 0.0 5.5e-06 26.2 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family zf-3CxxC PF13695.1 EEQ75310.1 - 4.3e-29 100.6 3.6 4.3e-29 100.6 2.5 2.4 2 1 0 2 2 2 1 Zinc-binding domain zf-C2H2_jaz PF12171.3 EEQ75310.1 - 1e-09 38.2 7.6 6.7e-05 22.9 0.3 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EEQ75310.1 - 4.9e-08 32.6 1.5 0.00082 19.1 0.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EEQ75310.1 - 6.4e-06 26.1 3.5 0.056 13.8 0.1 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 EEQ75310.1 - 8.6e-06 25.7 1.6 0.0027 17.8 0.3 4.5 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EEQ75310.1 - 4.8e-05 23.4 6.5 0.061 13.6 0.2 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EEQ75310.1 - 0.077 13.1 2.7 3.8 7.6 0.5 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.10 EEQ75310.1 - 0.12 11.7 0.9 0.7 9.3 0.1 2.3 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2HC_2 PF13913.1 EEQ75310.1 - 0.15 11.7 9.6 0.33 10.6 0.1 3.4 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 EEQ75310.1 - 1.2 9.5 0.1 1.2 9.5 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double domain Ceramidase PF05875.7 EEQ75311.1 - 9.5e-109 362.5 12.9 1.1e-108 362.3 9.0 1.0 1 0 0 1 1 1 1 Ceramidase Oxidored_q2 PF00420.19 EEQ75311.1 - 0.12 12.0 2.6 0.26 10.9 0.1 2.3 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Abhydrolase_6 PF12697.2 EEQ75312.1 - 1.6e-26 93.6 0.3 1.4e-25 90.5 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ75312.1 - 0.00013 21.7 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ75312.1 - 0.00085 18.9 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DJ-1_PfpI PF01965.19 EEQ75313.1 - 1.5e-25 89.3 0.1 2.1e-25 88.8 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EEQ75313.1 - 8.5e-16 57.2 0.0 1.7e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family ADH_N PF08240.7 EEQ75314.1 - 2.4e-20 72.3 2.1 5.7e-20 71.1 1.5 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ75314.1 - 6.3e-13 48.4 0.0 1.1e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EEQ75314.1 - 0.00048 19.3 0.1 0.00086 18.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EEQ75314.1 - 0.0036 16.8 0.2 0.046 13.2 0.1 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.12 EEQ75314.1 - 0.089 13.2 0.2 0.61 10.5 0.1 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent BRCT PF00533.21 EEQ75315.1 - 6.7e-36 122.2 0.2 6.9e-11 42.1 0.0 6.7 6 1 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EEQ75315.1 - 7.9e-32 108.9 1.0 1.1e-19 70.0 0.3 5.6 5 0 0 5 5 5 3 twin BRCT domain ESCRT-II PF05871.7 EEQ75316.1 - 6.8e-52 175.0 0.0 9.6e-52 174.5 0.0 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit Methyltransf_4 PF02390.12 EEQ75317.1 - 7.7e-48 162.1 0.0 1.7e-35 121.8 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 EEQ75317.1 - 1.4e-05 25.5 0.0 2.6e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ75317.1 - 0.0018 18.2 0.0 0.0037 17.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ75317.1 - 0.0082 15.5 0.0 0.23 10.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EEQ75317.1 - 0.025 14.9 0.0 0.07 13.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 EEQ75317.1 - 0.032 13.2 0.0 0.054 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_31 PF13847.1 EEQ75317.1 - 0.047 13.2 0.0 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ75317.1 - 0.074 13.5 0.0 1.5 9.3 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ75317.1 - 0.088 13.2 0.0 0.26 11.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain X PF00739.14 EEQ75317.1 - 0.11 12.4 1.8 0.18 11.6 1.2 1.3 1 0 0 1 1 1 0 Trans-activation protein X LIM PF00412.17 EEQ75318.1 - 3.3e-28 97.5 27.0 1.1e-10 41.4 0.2 4.2 4 0 0 4 4 4 3 LIM domain Zn_ribbon_recom PF13408.1 EEQ75318.1 - 0.11 12.7 0.1 0.11 12.7 0.1 2.6 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain SPOR PF05036.8 EEQ75318.1 - 0.13 12.4 0.0 0.41 10.8 0.0 1.8 1 0 0 1 1 1 0 Sporulation related domain DUF2321 PF10083.4 EEQ75318.1 - 1.1 8.7 5.4 0.27 10.7 1.2 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) MFS_1 PF07690.11 EEQ75320.1 - 6.1e-26 90.9 42.2 9.6e-26 90.3 29.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily RNB PF00773.14 EEQ75321.1 - 1.1e-91 307.5 0.1 1.1e-91 307.5 0.1 1.6 2 0 0 2 2 2 1 RNB domain PIN_4 PF13638.1 EEQ75321.1 - 7.9e-11 42.1 0.1 3e-10 40.3 0.1 2.0 1 0 0 1 1 1 1 PIN domain CN_hydrolase PF00795.17 EEQ75322.1 - 7.6e-27 93.8 0.0 1.2e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ESSS PF10183.4 EEQ75323.1 - 1.2e-28 99.5 0.1 1.3e-28 99.4 0.1 1.0 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ACOX PF01756.14 EEQ75324.1 - 1.3e-38 132.2 0.0 3.2e-38 130.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EEQ75324.1 - 6.1e-26 91.1 0.5 1.4e-25 90.0 0.3 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EEQ75324.1 - 5.4e-11 41.8 0.2 1.7e-10 40.2 0.2 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EEQ75324.1 - 4.9e-05 23.4 0.3 0.00049 20.2 0.2 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AIP3 PF03915.8 EEQ75326.1 - 7.6e-157 522.5 1.7 1.4e-156 521.7 1.2 1.4 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.9 EEQ75326.1 - 0.051 12.9 0.1 0.22 10.9 0.1 2.2 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain FliL PF03748.9 EEQ75326.1 - 0.057 13.4 1.2 0.2 11.7 0.1 2.4 2 0 0 2 2 2 0 Flagellar basal body-associated protein FliL DUF1664 PF07889.7 EEQ75326.1 - 0.13 12.0 0.6 0.48 10.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Desmo_N PF06771.6 EEQ75326.1 - 0.16 11.9 0.2 0.74 9.7 0.0 2.1 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus CAS_CSE1 PF03378.10 EEQ75326.1 - 0.26 9.5 1.1 0.35 9.1 0.2 1.5 2 0 0 2 2 2 0 CAS/CSE protein, C-terminus LsmAD PF06741.8 EEQ75327.1 - 5.8e-27 93.5 5.9 1.4e-26 92.3 4.1 1.7 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 EEQ75327.1 - 1e-14 54.1 0.0 2.7e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain Pkinase PF00069.20 EEQ75329.1 - 5.1e-08 32.3 0.0 1.1e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 EEQ75329.1 - 2e-07 30.4 2.4 0.066 13.3 0.0 5.4 6 0 0 6 6 6 2 HEAT repeat Pkinase_Tyr PF07714.12 EEQ75329.1 - 1.6e-05 24.1 0.0 2.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 EEQ75329.1 - 2.7e-05 24.5 0.2 0.046 14.2 0.0 3.3 3 0 0 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.1 EEQ75329.1 - 0.0013 18.9 0.1 0.29 11.4 0.0 3.7 2 1 2 4 4 4 2 HEAT repeats Kinase-like PF14531.1 EEQ75329.1 - 0.029 13.3 0.0 0.051 12.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Adaptin_N PF01602.15 EEQ75329.1 - 0.1 10.8 0.0 0.24 9.6 0.0 1.4 1 1 0 1 1 1 0 Adaptin N terminal region Cnd1 PF12717.2 EEQ75329.1 - 0.14 11.9 0.0 0.7 9.7 0.0 1.9 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 CoA_trans PF01144.18 EEQ75329.1 - 0.15 11.2 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Coenzyme A transferase adh_short PF00106.20 EEQ75331.1 - 2.1e-27 96.0 0.1 3.2e-27 95.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ75331.1 - 8.7e-22 78.0 0.0 1.4e-20 74.1 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ75331.1 - 1e-10 41.5 0.4 3.5e-10 39.8 0.3 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EEQ75331.1 - 0.00011 21.7 0.0 0.015 14.7 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EEQ75331.1 - 0.019 14.1 0.0 1.1 8.2 0.0 2.0 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) NAD_binding_4 PF07993.7 EEQ75331.1 - 0.073 11.9 0.0 0.16 10.8 0.0 1.5 1 1 0 1 1 1 0 Male sterility protein RmlD_sub_bind PF04321.12 EEQ75331.1 - 0.14 10.9 0.0 0.38 9.5 0.0 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain DUF4646 PF15496.1 EEQ75332.1 - 0.037 14.0 0.3 0.15 12.0 0.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4646) Nup88 PF10168.4 EEQ75332.1 - 0.52 8.0 6.9 0.85 7.3 4.8 1.2 1 0 0 1 1 1 0 Nuclear pore component Acetyltransf_1 PF00583.19 EEQ75333.1 - 2.9e-13 49.6 0.1 4.7e-13 48.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EEQ75333.1 - 4e-07 29.7 0.0 6.2e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EEQ75333.1 - 0.0045 17.1 0.0 0.0073 16.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEQ75333.1 - 0.014 15.2 0.2 0.025 14.4 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEQ75333.1 - 0.019 15.1 0.0 0.031 14.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NAM-associated PF14303.1 EEQ75333.1 - 0.035 14.4 3.1 0.048 13.9 0.8 1.9 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain SUR7 PF06687.7 EEQ75335.1 - 1.7e-41 142.1 10.2 2.1e-41 141.8 7.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 EEQ75335.1 - 0.11 12.3 14.9 0.073 12.9 7.7 2.0 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Shisa PF13908.1 EEQ75335.1 - 3.4 7.8 8.3 0.95 9.6 0.8 2.7 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator adh_short_C2 PF13561.1 EEQ75336.1 - 2.2e-29 102.9 0.2 2.6e-29 102.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEQ75336.1 - 3.3e-29 101.9 1.4 4.5e-29 101.5 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ75336.1 - 1.4e-13 50.8 0.8 1.9e-13 50.4 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEQ75336.1 - 2.5e-06 27.1 1.0 8.2e-06 25.4 0.7 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EEQ75336.1 - 5.3e-06 26.1 0.2 7.8e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EEQ75336.1 - 4.8e-05 22.4 0.2 6.9e-05 21.8 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.13 EEQ75336.1 - 9.2e-05 22.4 0.3 0.00021 21.2 0.2 1.6 1 1 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 EEQ75336.1 - 0.00017 20.6 0.3 0.00026 20.1 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 EEQ75336.1 - 0.00085 19.7 0.8 0.0018 18.6 0.6 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.7 EEQ75336.1 - 0.0014 17.6 0.1 0.0019 17.1 0.1 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EEQ75336.1 - 0.0017 18.4 1.0 0.003 17.5 0.7 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_2 PF03446.10 EEQ75336.1 - 0.0018 18.1 0.3 0.003 17.4 0.2 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EEQ75336.1 - 0.0034 17.1 0.1 0.0088 15.7 0.1 1.7 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EEQ75336.1 - 0.0044 16.4 0.1 0.0082 15.5 0.1 1.4 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DapB_N PF01113.15 EEQ75336.1 - 0.012 15.4 0.6 0.022 14.6 0.4 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.18 EEQ75336.1 - 0.017 14.9 0.1 0.034 13.9 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EEQ75336.1 - 0.037 12.7 0.1 0.053 12.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ApbA PF02558.11 EEQ75336.1 - 0.074 12.5 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Mannitol_dh PF01232.18 EEQ75336.1 - 0.09 12.7 0.2 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain NAD_binding_3 PF03447.11 EEQ75336.1 - 0.12 12.7 0.3 0.22 11.9 0.2 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain WD40 PF00400.27 EEQ75338.1 - 1.6e-44 148.2 16.6 6.7e-12 44.8 0.1 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EEQ75338.1 - 3.3e-07 28.8 8.0 0.094 10.8 0.1 4.9 3 1 1 5 5 5 4 Nucleoporin Nup120/160 Hira PF07569.6 EEQ75338.1 - 0.019 14.2 0.2 7.2 5.7 0.0 3.2 2 1 2 4 4 4 0 TUP1-like enhancer of split DUF3312 PF11768.3 EEQ75338.1 - 0.037 12.2 0.0 0.058 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DUF1513 PF07433.6 EEQ75338.1 - 0.039 12.8 0.6 2.2 7.0 0.0 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1513) Tctex-1 PF03645.8 EEQ75339.1 - 2.7e-33 113.8 0.0 3.2e-33 113.6 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.10 EEQ75340.1 - 4.4e-12 46.0 5.2 4.4e-12 46.0 3.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2207 PF09972.4 EEQ75340.1 - 0.024 13.2 0.3 0.032 12.8 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2615 PF11027.3 EEQ75340.1 - 0.15 12.0 1.0 0.39 10.6 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) Mucin PF01456.12 EEQ75343.1 - 0.019 14.7 9.8 0.031 14.0 6.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.6 EEQ75343.1 - 0.24 11.1 21.7 0.32 10.7 15.1 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) CFEM PF05730.6 EEQ75343.1 - 1.4 8.8 10.7 3.4 7.5 7.4 1.8 1 1 0 1 1 1 0 CFEM domain MSA-2c PF12238.3 EEQ75343.1 - 9.2 5.8 6.8 14 5.2 4.7 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c HECT PF00632.20 EEQ75344.1 - 1.5e-94 316.7 0.1 2.2e-94 316.1 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EEQ75344.1 - 4.8e-33 112.6 20.4 4.3e-11 42.4 2.6 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EEQ75344.1 - 6e-13 48.4 0.1 5e-12 45.4 0.0 2.3 2 0 0 2 2 2 1 C2 domain RRM_1 PF00076.17 EEQ75345.1 - 3.1e-16 58.7 0.0 5e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ75345.1 - 9.8e-14 51.0 0.1 3e-13 49.5 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ75345.1 - 8.9e-05 22.2 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CASP_C PF08172.7 EEQ75345.1 - 0.0066 15.5 0.1 0.0088 15.1 0.0 1.1 1 0 0 1 1 1 1 CASP C terminal IncA PF04156.9 EEQ75345.1 - 0.015 14.8 1.6 0.019 14.5 1.1 1.1 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 EEQ75345.1 - 0.044 14.0 3.3 0.07 13.4 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) V_ATPase_I PF01496.14 EEQ75345.1 - 0.047 11.5 0.1 0.052 11.3 0.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EEQ75345.1 - 0.14 11.2 0.9 0.15 11.0 0.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 EEQ75345.1 - 0.36 10.3 4.5 0.56 9.7 3.1 1.3 1 0 0 1 1 1 0 Septum formation initiator Troponin PF00992.15 EEQ75345.1 - 0.55 10.3 8.4 0.77 9.8 5.8 1.1 1 0 0 1 1 1 0 Troponin DUF4140 PF13600.1 EEQ75345.1 - 1.1 9.7 4.0 2.2 8.7 2.8 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4337 PF14235.1 EEQ75345.1 - 1.9 8.3 4.4 2.5 7.9 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Metallophos_2 PF12850.2 EEQ75346.1 - 2.1e-15 56.9 0.0 2.5e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aminotran_5 PF00266.14 EEQ75347.1 - 6e-29 100.9 0.0 8e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 EEQ75347.1 - 0.13 12.1 0.3 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 B12 binding domain Myosin_head PF00063.16 EEQ75348.1 - 1.4e-231 770.3 2.3 2.1e-231 769.7 1.6 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EEQ75348.1 - 1.4e-47 161.6 0.0 2.5e-47 160.7 0.0 1.5 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 EEQ75348.1 - 1.8e-13 49.6 0.1 3.3e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EEQ75348.1 - 1.5e-09 37.2 0.0 3.7e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EEQ75348.1 - 3e-08 33.1 0.0 7.9e-08 31.7 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 EEQ75348.1 - 0.0016 18.6 0.0 0.0084 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain IQ PF00612.22 EEQ75348.1 - 0.0038 16.7 7.3 0.47 10.2 0.7 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_17 PF13207.1 EEQ75348.1 - 0.013 16.2 0.0 0.042 14.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.7 EEQ75348.1 - 0.016 14.5 0.3 1.5 8.1 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Zeta_toxin PF06414.7 EEQ75348.1 - 0.024 13.7 0.0 0.057 12.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EEQ75348.1 - 0.05 13.9 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EEQ75348.1 - 0.072 13.2 0.2 0.38 10.9 0.0 2.2 2 0 0 2 2 2 0 RNA helicase DUF2075 PF09848.4 EEQ75348.1 - 0.082 11.8 0.1 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.4 EEQ75348.1 - 0.089 11.3 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 EEQ75348.1 - 0.17 11.5 0.0 0.4 10.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain GreA_GreB_N PF03449.10 EEQ75349.1 - 0.026 14.5 1.5 0.03 14.3 0.2 1.7 1 1 0 1 1 1 0 Transcription elongation factor, N-terminal DUF3897 PF13036.1 EEQ75349.1 - 0.027 14.1 0.4 0.03 13.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3897) OPA3 PF07047.7 EEQ75350.1 - 1.4e-31 109.0 2.7 4.3e-31 107.4 1.9 1.9 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) COX16 PF14138.1 EEQ75350.1 - 4.4 7.5 5.4 2 8.6 0.4 2.6 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Pkinase PF00069.20 EEQ75351.1 - 1e-57 195.3 0.0 9.9e-57 192.0 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ75351.1 - 1.2e-36 126.1 0.0 2e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EEQ75351.1 - 1e-06 28.6 0.1 0.07 13.1 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 EEQ75351.1 - 0.01 14.8 0.0 0.021 13.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EEQ75351.1 - 0.044 12.8 0.0 0.091 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family 2-Hacid_dh_C PF02826.14 EEQ75352.1 - 3.4e-41 140.3 0.1 3.8e-27 94.5 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EEQ75352.1 - 0.0068 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 2-Hacid_dh PF00389.25 EEQ75352.1 - 0.014 14.8 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3HCDH_N PF02737.13 EEQ75352.1 - 0.017 14.7 0.1 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Gp_dh_N PF00044.19 EEQ75352.1 - 0.018 14.9 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EEQ75352.1 - 0.023 15.1 0.0 0.052 13.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DHDPS PF00701.17 EEQ75353.1 - 7.9e-37 126.4 0.0 9.5e-37 126.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family zf-DHHC PF01529.15 EEQ75355.1 - 0.016 14.6 0.6 0.4 10.0 0.2 2.3 1 1 1 2 2 2 0 DHHC palmitoyltransferase DNA_mis_repair PF01119.14 EEQ75356.1 - 6.9e-11 41.6 0.0 2.3e-10 39.9 0.0 1.9 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 EEQ75356.1 - 1.6e-10 40.6 0.0 5.3e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EEQ75356.1 - 8.7e-10 38.3 0.0 2.3e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SET PF00856.23 EEQ75357.1 - 1e-07 32.4 0.0 6.8e-07 29.7 0.0 1.9 1 1 0 2 2 2 1 SET domain SAF PF08666.7 EEQ75357.1 - 0.0044 17.3 0.0 0.76 10.2 0.0 2.6 3 0 0 3 3 3 2 SAF domain cobW PF02492.14 EEQ75358.1 - 2.2e-37 128.2 0.0 3.2e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EEQ75358.1 - 0.018 15.3 0.1 0.054 13.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EEQ75358.1 - 0.036 13.8 0.0 0.098 12.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 EEQ75358.1 - 0.047 13.6 0.0 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EEQ75358.1 - 0.088 12.5 0.0 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EEQ75358.1 - 0.092 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EEQ75358.1 - 0.093 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.1 EEQ75358.1 - 0.1 12.1 0.0 1.5 8.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Orn_Arg_deC_N PF02784.11 EEQ75359.1 - 9.1e-79 264.1 0.0 1.5e-78 263.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EEQ75359.1 - 2.9e-29 101.1 0.0 4.8e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 EEQ75359.1 - 0.022 14.0 0.0 0.049 12.9 0.0 1.7 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Rho_N PF07498.7 EEQ75359.1 - 0.35 10.6 2.3 6.9 6.5 0.3 2.4 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain Methyltransf_16 PF10294.4 EEQ75360.1 - 8.5e-47 158.8 0.0 1.2e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EEQ75360.1 - 3.9e-05 23.4 0.0 8.3e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ75360.1 - 0.00032 20.3 0.0 0.0005 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ75360.1 - 0.00034 20.6 0.1 0.00073 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ75360.1 - 0.00086 19.8 0.0 0.0016 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ75360.1 - 0.0052 16.1 0.0 0.0087 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EEQ75360.1 - 0.0068 16.8 0.1 0.031 14.7 0.0 2.1 2 1 1 3 3 3 1 Methyltransferase domain B12-binding PF02310.14 EEQ75360.1 - 0.055 13.3 0.1 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain PrmA PF06325.8 EEQ75360.1 - 0.074 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) SOBP PF15279.1 EEQ75362.1 - 0.028 14.8 12.1 0.043 14.1 8.4 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2217 PF10265.4 EEQ75362.1 - 0.034 12.9 3.2 0.035 12.8 1.6 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Glypican PF01153.14 EEQ75362.1 - 1.6 7.2 4.3 3.3 6.2 3.0 1.5 1 0 0 1 1 1 0 Glypican DSBA PF01323.15 EEQ75363.1 - 1.3e-15 57.4 0.0 1.5e-15 57.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain PD40 PF07676.7 EEQ75366.1 - 0.021 14.4 0.1 0.05 13.2 0.0 1.7 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Gp58 PF07902.6 EEQ75367.1 - 0.0048 15.1 0.1 0.0068 14.6 0.0 1.1 1 0 0 1 1 1 1 gp58-like protein DUF3099 PF11298.3 EEQ75367.1 - 0.097 12.4 1.0 0.22 11.3 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) Mitofilin PF09731.4 EEQ75368.1 - 6.6e-156 520.3 26.5 9.7e-156 519.8 18.4 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Ribosomal_L20 PF00453.13 EEQ75368.1 - 0.084 12.8 0.8 0.24 11.3 0.5 1.8 1 1 0 1 1 1 0 Ribosomal protein L20 Exonuc_VII_L PF02601.10 EEQ75368.1 - 0.29 10.3 11.8 0.044 12.9 5.4 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Prominin PF05478.6 EEQ75368.1 - 1.4 6.3 6.0 2.3 5.6 4.2 1.3 1 0 0 1 1 1 0 Prominin DUF2115 PF09888.4 EEQ75368.1 - 5.1 7.1 6.0 9.4 6.3 1.7 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Ras PF00071.17 EEQ75369.1 - 4.3e-59 198.5 0.2 5e-59 198.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ75369.1 - 3.4e-20 72.7 0.1 6.5e-20 71.8 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EEQ75369.1 - 1e-14 54.1 0.0 1.3e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEQ75369.1 - 5.9e-08 32.1 0.0 7.3e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EEQ75369.1 - 1.2e-07 31.3 0.0 2.3e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEQ75369.1 - 4.6e-06 26.5 0.0 6.1e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EEQ75369.1 - 0.0089 16.1 0.0 0.62 10.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEQ75369.1 - 0.022 14.7 0.3 0.11 12.4 0.1 2.1 1 1 1 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EEQ75369.1 - 0.028 13.6 0.1 0.1 11.8 0.0 1.9 1 1 0 2 2 2 0 Protein of unknown function, DUF258 SRPRB PF09439.5 EEQ75369.1 - 0.046 12.9 0.1 0.094 11.9 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EEQ75369.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain Syja_N PF02383.13 EEQ75370.1 - 7e-93 310.8 0.0 8.8e-93 310.5 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Mur_ligase_M PF08245.7 EEQ75371.1 - 5.7e-06 26.5 0.0 0.031 14.3 0.0 2.9 2 1 0 2 2 2 2 Mur ligase middle domain NMT PF01233.14 EEQ75372.1 - 1.6e-81 271.6 0.0 2.5e-81 271.0 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EEQ75372.1 - 1e-74 250.0 0.0 2.1e-74 249.0 0.0 1.5 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EEQ75372.1 - 1.6e-06 28.0 0.0 1.3e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain TLD PF07534.11 EEQ75373.1 - 1.2e-18 67.3 0.6 4.2e-18 65.6 0.4 1.9 1 1 0 1 1 1 1 TLD Med3 PF11593.3 EEQ75373.1 - 0.4 9.8 3.2 0.64 9.2 2.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pkinase PF00069.20 EEQ75376.1 - 4e-06 26.1 0.0 6.3e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EEQ75376.1 - 0.00067 18.7 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ75376.1 - 0.012 15.3 0.1 3.3 7.3 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ75376.1 - 0.045 13.3 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Abhydrolase_5 PF12695.2 EEQ75377.1 - 1.8e-11 44.0 0.0 4.5e-11 42.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ75377.1 - 2.6e-11 43.8 1.3 4.5e-11 43.0 0.9 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EEQ75377.1 - 5e-07 29.5 0.3 7.9e-07 28.8 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EEQ75377.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EEQ75377.1 - 0.0015 18.3 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DUF818 PF05677.7 EEQ75377.1 - 0.12 11.1 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Viral_Beta_CD PF04530.7 EEQ75377.1 - 0.17 12.0 0.1 0.34 11.0 0.1 1.4 1 0 0 1 1 1 0 Viral Beta C/D like family GTP_EFTU PF00009.22 EEQ75378.1 - 2.7e-56 189.9 0.4 6.3e-56 188.7 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EEQ75378.1 - 7.9e-33 112.1 0.0 1.6e-32 111.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EEQ75378.1 - 1.4e-31 108.4 0.1 2.6e-31 107.6 0.1 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EEQ75378.1 - 1.5e-22 79.2 0.0 4.5e-22 77.7 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EEQ75378.1 - 1.3e-12 47.5 0.0 4e-12 46.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 ATP_bind_1 PF03029.12 EEQ75378.1 - 0.018 14.5 0.1 0.07 12.6 0.0 2.0 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein PALP PF00291.20 EEQ75380.1 - 3.5e-74 249.8 0.5 4.3e-74 249.4 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EEQ75380.1 - 1.5e-43 146.2 0.0 5e-22 77.3 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HIG_1_N PF04588.8 EEQ75381.1 - 1.2e-20 72.9 0.0 1.6e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region OPA3 PF07047.7 EEQ75381.1 - 0.038 13.7 1.0 0.058 13.1 0.2 1.5 1 1 0 1 1 1 0 Optic atrophy 3 protein (OPA3) MAS20 PF02064.10 EEQ75381.1 - 0.04 13.8 1.3 0.055 13.3 0.9 1.3 1 0 0 1 1 1 0 MAS20 protein import receptor Complex1_LYR PF05347.10 EEQ75382.1 - 1.1e-11 44.3 0.2 1.8e-11 43.6 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EEQ75382.1 - 1.4e-11 44.4 0.6 2e-11 43.8 0.4 1.3 1 0 0 1 1 1 1 Complex1_LYR-like GNAT_acetyltran PF12746.2 EEQ75382.1 - 0.11 11.2 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase DUF1375 PF07119.7 EEQ75382.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1375) Acetyltransf_1 PF00583.19 EEQ75383.1 - 1.4e-14 53.8 0.3 2.3e-14 53.1 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EEQ75383.1 - 0.00011 21.9 0.0 0.00027 20.6 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EEQ75383.1 - 0.00013 22.0 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEQ75383.1 - 0.0043 17.1 0.4 0.0078 16.3 0.3 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EEQ75383.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PIG-U PF06728.8 EEQ75384.1 - 7.5e-120 400.2 31.9 8.6e-120 400.0 22.1 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Pescadillo_N PF06732.6 EEQ75385.1 - 2.5e-113 378.0 0.0 2.5e-113 378.0 0.0 2.1 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 EEQ75385.1 - 1.1e-08 35.0 0.0 1.2e-07 31.8 0.0 2.6 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RRN9 PF10680.4 EEQ75386.1 - 1.9e-21 75.5 0.7 5.2e-21 74.1 0.5 1.7 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor zf-C2H2_4 PF13894.1 EEQ75386.1 - 0.01 16.1 0.3 0.028 14.7 0.2 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ75386.1 - 0.089 13.1 0.4 0.25 11.7 0.2 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Uma2 PF05685.7 EEQ75387.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative restriction endonuclease APH PF01636.18 EEQ75388.1 - 1.8e-05 24.6 0.1 0.00014 21.7 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ75388.1 - 0.00088 18.9 1.3 0.0017 17.9 1.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EEQ75388.1 - 0.0071 15.5 0.5 0.019 14.1 0.3 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase RTC4 PF14474.1 EEQ75389.1 - 7.3e-27 93.7 0.0 9e-27 93.4 0.0 1.1 1 0 0 1 1 1 1 RTC4-like domain Pkinase PF00069.20 EEQ75390.1 - 8.2e-09 34.9 0.0 1.6e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ75390.1 - 0.064 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.18 EEQ75390.1 - 0.081 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EEQ75390.1 - 0.13 11.5 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF2263 PF10021.4 EEQ75391.1 - 4.9e-26 91.4 0.0 7.8e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Aldedh PF00171.17 EEQ75392.1 - 1.7e-163 544.2 0.4 2e-163 544.0 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EEQ75392.1 - 0.1 11.7 0.0 0.53 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) LuxC PF05893.9 EEQ75392.1 - 0.15 10.7 0.1 0.34 9.5 0.0 1.6 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Raffinose_syn PF05691.7 EEQ75393.1 - 2.2e-51 174.3 2.9 1.2e-48 165.3 2.0 3.0 1 1 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 EEQ75393.1 - 8e-05 21.4 1.0 0.00013 20.8 0.7 1.2 1 0 0 1 1 1 1 Melibiase tRNA-synt_1b PF00579.20 EEQ75394.1 - 1e-67 228.3 0.0 1.6e-67 227.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Acetyltransf_6 PF13480.1 EEQ75394.1 - 0.012 15.6 0.1 0.046 13.6 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MutS_V PF00488.16 EEQ75395.1 - 3e-68 229.7 0.0 6.9e-68 228.5 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EEQ75395.1 - 6.8e-52 176.2 0.1 1.2e-51 175.3 0.1 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EEQ75395.1 - 3.5e-33 113.9 0.1 1.2e-32 112.2 0.0 2.0 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 EEQ75395.1 - 2.7e-16 59.5 0.4 6.1e-16 58.3 0.3 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EEQ75395.1 - 1.1e-12 48.2 0.0 3.9e-12 46.4 0.0 2.0 1 0 0 1 1 1 1 MutS domain II SPT6_acidic PF14632.1 EEQ75395.1 - 0.0037 17.3 8.5 0.011 15.8 5.9 1.8 1 0 0 1 1 1 1 Acidic N-terminal SPT6 Filament PF00038.16 EEQ75395.1 - 0.039 13.4 0.1 0.077 12.4 0.1 1.4 1 0 0 1 1 1 0 Intermediate filament protein Rhodanese PF00581.15 EEQ75396.1 - 2.4e-07 31.0 0.0 4.9e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 Rhodanese-like domain ORC6 PF05460.8 EEQ75397.1 - 0.032 13.3 0.2 0.032 13.3 0.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Herpes_BLLF1 PF05109.8 EEQ75397.1 - 0.036 12.0 2.3 0.043 11.7 1.6 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Peptidase_M28 PF04389.12 EEQ75399.1 - 9.5e-34 116.6 0.0 1.4e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Sulf_transp PF04143.9 EEQ75400.1 - 4.1e-12 45.9 14.2 2.3e-07 30.7 4.0 4.1 5 0 0 5 5 5 2 Sulphur transport DUF4341 PF14241.1 EEQ75400.1 - 5.8e-09 35.5 0.4 5.8e-09 35.5 0.3 3.5 3 1 0 3 3 3 1 Domain of unknown function (DUF4341) ABC_tran PF00005.22 EEQ75402.1 - 4.5e-49 166.2 0.0 6e-30 104.3 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEQ75402.1 - 7.5e-37 127.2 33.3 1.8e-23 83.3 10.0 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EEQ75402.1 - 3.6e-10 39.4 0.4 0.022 13.9 0.0 4.5 4 1 1 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EEQ75402.1 - 7.3e-05 23.1 1.1 0.0026 18.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EEQ75402.1 - 9.7e-05 21.8 1.8 0.16 11.4 0.2 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EEQ75402.1 - 0.00029 20.8 1.2 0.13 12.1 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 EEQ75402.1 - 0.0003 20.2 0.2 0.51 9.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EEQ75402.1 - 0.0006 19.0 0.1 0.83 8.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 EEQ75402.1 - 0.00076 19.0 0.4 0.78 9.1 0.0 2.7 3 0 0 3 3 3 2 AAA-like domain AAA_22 PF13401.1 EEQ75402.1 - 0.0011 19.1 0.1 4.2 7.5 0.0 3.6 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 EEQ75402.1 - 0.0013 18.6 0.2 0.43 10.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EEQ75402.1 - 0.0023 18.4 0.2 4.2 7.8 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein T2SE PF00437.15 EEQ75402.1 - 0.004 16.1 0.1 0.69 8.7 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein ArgK PF03308.11 EEQ75402.1 - 0.0065 15.2 0.1 0.016 13.9 0.0 1.6 1 0 0 1 1 1 1 ArgK protein DUF87 PF01935.12 EEQ75402.1 - 0.0093 15.7 4.2 0.64 9.7 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 Zeta_toxin PF06414.7 EEQ75402.1 - 0.013 14.6 0.4 1.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_21 PF13304.1 EEQ75402.1 - 0.014 15.4 1.9 5.8 6.7 0.0 3.6 3 1 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.13 EEQ75402.1 - 0.023 14.2 0.0 0.088 12.3 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MobB PF03205.9 EEQ75402.1 - 0.097 12.3 0.9 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EEQ75402.1 - 0.14 13.0 1.2 12 6.7 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EEQ75402.1 - 0.17 12.1 0.1 13 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain CbiA PF01656.18 EEQ75402.1 - 0.19 11.1 0.7 9.4 5.5 0.0 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain FtsK_SpoIIIE PF01580.13 EEQ75402.1 - 0.2 11.1 0.1 7.4 5.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AIG1 PF04548.11 EEQ75402.1 - 0.3 10.1 0.7 6.6 5.7 0.0 2.3 2 0 0 2 2 2 0 AIG1 family GMC_oxred_N PF00732.14 EEQ75403.1 - 7.2e-54 182.9 0.0 9.3e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EEQ75403.1 - 9e-31 107.1 0.1 1.5e-30 106.4 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EEQ75403.1 - 2.7e-05 23.2 0.0 0.12 11.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EEQ75403.1 - 0.0018 17.2 0.0 0.004 16.1 0.0 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EEQ75403.1 - 0.0024 16.8 0.1 0.57 8.9 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain CBM_11 PF03425.8 EEQ75403.1 - 0.0032 17.1 0.2 0.0064 16.1 0.2 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) NAD_binding_8 PF13450.1 EEQ75403.1 - 0.0075 16.2 0.1 0.02 14.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EEQ75403.1 - 0.017 14.0 0.1 1.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 EEQ75403.1 - 0.017 13.6 0.0 0.65 8.3 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.9 EEQ75403.1 - 0.052 13.4 0.1 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEQ75403.1 - 0.063 13.3 0.0 4.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4141 PF13605.1 EEQ75404.1 - 0.031 13.4 0.2 2.6 7.3 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4141) PEP_mutase PF13714.1 EEQ75405.1 - 1.1e-62 211.3 0.4 1.3e-62 211.1 0.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ComA PF02679.10 EEQ75405.1 - 0.041 12.8 0.0 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) PC_rep PF01851.17 EEQ75406.1 - 7.8e-36 120.3 15.9 5.4e-09 35.7 0.0 9.6 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EEQ75406.1 - 3.5e-19 68.8 0.6 8.3e-13 48.4 0.0 4.3 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 EEQ75406.1 - 5.7e-08 32.1 0.0 3.3 8.0 0.0 6.0 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EEQ75406.1 - 5e-07 30.0 0.3 5e-05 23.6 0.0 4.1 2 1 1 3 3 3 1 HEAT-like repeat HEAT_PBS PF03130.11 EEQ75406.1 - 0.084 13.3 1.4 1.6 9.4 0.0 3.8 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat ERO1 PF04137.10 EEQ75406.1 - 3.1 6.7 5.6 0.26 10.2 0.0 1.9 2 0 0 2 2 2 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Acyl-CoA_dh_1 PF00441.19 EEQ75407.1 - 1.4e-39 135.5 0.4 2e-39 135.0 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EEQ75407.1 - 4.6e-20 70.8 0.1 8.3e-20 70.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EEQ75407.1 - 1.6e-18 66.2 0.1 3.1e-18 65.3 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EEQ75407.1 - 1.6e-18 67.3 0.0 3.1e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EEQ75407.1 - 3.7e-08 33.6 0.1 7e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain C6 PF01681.12 EEQ75407.1 - 0.041 13.9 0.3 0.19 11.7 0.1 2.1 2 0 0 2 2 2 0 C6 domain CAP_N PF01213.14 EEQ75407.1 - 3.7 6.7 5.8 6 6.0 4.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Spt5-NGN PF03439.8 EEQ75408.1 - 3.4e-25 87.6 0.0 6.3e-25 86.7 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.2 EEQ75408.1 - 1.1e-23 83.9 50.7 4.3e-22 78.8 26.4 3.7 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.3 EEQ75408.1 - 2.5e-16 60.0 8.7 2.5e-16 60.0 6.0 3.8 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 EEQ75408.1 - 2.7e-12 45.8 10.0 0.0036 16.9 0.1 4.7 4 0 0 4 4 4 3 KOW motif CS PF04969.11 EEQ75409.1 - 1.1e-16 61.1 0.0 1.8e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 CS domain tRNA-synt_2 PF00152.15 EEQ75410.1 - 3.2e-103 345.0 0.0 4.2e-103 344.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EEQ75410.1 - 0.021 14.4 0.1 0.039 13.5 0.1 1.4 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Histone PF00125.19 EEQ75411.1 - 0.0027 17.7 0.1 0.0039 17.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 NDUF_B7 PF05676.8 EEQ75411.1 - 0.031 13.6 2.0 0.047 13.1 0.7 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DUF1664 PF07889.7 EEQ75414.1 - 0.0093 15.7 1.1 0.0093 15.7 0.7 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.17 EEQ75414.1 - 0.42 10.6 14.9 0.03 14.3 1.8 4.1 3 2 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.5 EEQ75414.1 - 0.48 10.5 7.6 0.083 13.0 0.7 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.7 EEQ75414.1 - 4.4 7.1 7.9 1.1 9.0 0.6 3.0 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Abhydrolase_5 PF12695.2 EEQ75415.1 - 9.3e-09 35.1 0.0 4.7e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ75415.1 - 9.2e-08 32.2 0.1 2.9e-07 30.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ75415.1 - 0.00065 19.3 0.1 0.022 14.2 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEQ75415.1 - 0.0032 16.7 0.0 0.17 11.1 0.0 2.9 3 0 0 3 3 3 1 Prolyl oligopeptidase family DUF318 PF03773.8 EEQ75415.1 - 0.012 14.6 0.7 0.02 13.8 0.5 1.2 1 0 0 1 1 1 0 Predicted permease Peptidase_S15 PF02129.13 EEQ75415.1 - 0.029 13.7 0.1 0.085 12.2 0.0 1.8 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3336 PF11815.3 EEQ75416.1 - 4.7e-41 139.6 1.1 7.9e-41 138.9 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EEQ75416.1 - 6.9e-22 78.3 0.0 6.9e-22 78.3 0.0 2.0 2 1 0 2 2 2 1 Patatin-like phospholipase Phage_H_T_join PF05521.6 EEQ75416.1 - 0.057 13.7 0.1 0.29 11.4 0.0 2.2 2 0 0 2 2 2 0 Phage head-tail joining protein Lpp-LpqN PF10738.4 EEQ75417.1 - 0.033 13.4 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 Probable lipoprotein LpqN TMEM154 PF15102.1 EEQ75420.1 - 3.9e-06 26.6 0.0 8.2e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family Herpes_gE PF02480.11 EEQ75420.1 - 0.0038 15.5 0.0 0.0062 14.8 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF3481 PF11980.3 EEQ75420.1 - 0.0076 16.0 0.0 0.1 12.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3481) CD34_antigen PF06365.7 EEQ75420.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Herpes_UL43 PF05072.8 EEQ75420.1 - 0.091 11.4 0.1 0.14 10.9 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL43 protein Med8 PF10232.4 EEQ75421.1 - 8.2e-47 159.5 0.0 1.2e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 PQ-loop PF04193.9 EEQ75422.1 - 9.8e-20 69.8 7.3 8.8e-12 44.3 0.8 2.7 3 0 0 3 3 3 2 PQ loop repeat UbiA PF01040.13 EEQ75423.1 - 1.8e-35 122.4 18.9 1.8e-35 122.4 13.1 1.9 1 1 1 2 2 2 1 UbiA prenyltransferase family Fungal_trans_2 PF11951.3 EEQ75425.1 - 2.6e-65 220.5 0.3 5.3e-65 219.4 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ75425.1 - 1.5e-09 37.5 9.9 2.8e-09 36.7 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.22 EEQ75426.1 - 1.1e-50 171.4 0.1 1e-24 87.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 EEQ75426.1 - 7.2e-47 159.2 47.7 1.7e-26 92.6 11.0 2.7 3 0 0 3 3 2 2 ABC-2 type transporter AAA_21 PF13304.1 EEQ75426.1 - 6e-18 65.8 0.1 5.8e-05 23.1 0.0 4.2 4 0 0 4 4 4 3 AAA domain AAA_15 PF13175.1 EEQ75426.1 - 2e-09 37.0 0.0 0.11 11.5 0.0 4.1 4 0 0 4 4 4 3 AAA ATPase domain AAA_25 PF13481.1 EEQ75426.1 - 4e-09 36.1 0.1 0.0028 17.1 0.0 3.1 4 0 0 4 4 3 2 AAA domain AAA_23 PF13476.1 EEQ75426.1 - 4.7e-09 36.8 0.0 0.003 17.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EEQ75426.1 - 9.6e-09 35.4 0.2 0.0027 17.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EEQ75426.1 - 3.8e-08 32.8 1.0 0.067 12.4 0.2 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EEQ75426.1 - 1e-07 31.2 0.8 0.013 14.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EEQ75426.1 - 3.5e-07 29.6 2.5 0.0015 18.0 0.4 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EEQ75426.1 - 1.4e-06 29.1 0.0 0.049 14.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EEQ75426.1 - 8e-06 25.6 0.2 0.024 14.2 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.1 EEQ75426.1 - 8.7e-06 25.7 0.1 0.068 13.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EEQ75426.1 - 1.4e-05 25.1 0.0 0.11 12.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 EEQ75426.1 - 1.7e-05 24.4 0.2 0.12 12.1 0.1 2.7 2 0 0 2 2 2 2 Part of AAA domain AAA PF00004.24 EEQ75426.1 - 3.9e-05 23.8 0.2 0.27 11.4 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EEQ75426.1 - 6.2e-05 22.0 0.1 0.21 10.4 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Arch_ATPase PF01637.13 EEQ75426.1 - 0.00012 21.8 0.0 0.055 13.1 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase Miro PF08477.8 EEQ75426.1 - 0.00017 22.0 0.5 0.34 11.4 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein cobW PF02492.14 EEQ75426.1 - 0.00032 20.2 1.3 0.12 11.7 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EEQ75426.1 - 0.0004 20.6 0.1 0.29 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EEQ75426.1 - 0.00077 19.0 0.1 1.1 8.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EEQ75426.1 - 0.0015 18.5 1.4 0.048 13.6 0.2 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP-synt_ab PF00006.20 EEQ75426.1 - 0.0016 18.0 0.1 1.2 8.5 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.1 EEQ75426.1 - 0.0021 17.9 0.6 1.9 8.4 0.0 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 EEQ75426.1 - 0.0021 18.2 0.1 0.58 10.3 0.0 2.4 2 0 0 2 2 2 1 RNA helicase Pox_A32 PF04665.7 EEQ75426.1 - 0.0023 17.2 0.4 1.3 8.2 0.0 2.3 2 0 0 2 2 2 1 Poxvirus A32 protein PDR_CDR PF06422.7 EEQ75426.1 - 0.0034 17.0 0.4 0.0095 15.5 0.3 1.7 1 0 0 1 1 1 1 CDR ABC transporter FtsK_SpoIIIE PF01580.13 EEQ75426.1 - 0.0038 16.7 0.4 0.18 11.2 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 EEQ75426.1 - 0.0039 16.6 4.5 0.39 10.1 0.6 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_33 PF13671.1 EEQ75426.1 - 0.0039 17.0 0.1 0.41 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EEQ75426.1 - 0.0044 16.7 0.1 1.3 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MobB PF03205.9 EEQ75426.1 - 0.0061 16.2 0.4 1.2 8.8 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 EEQ75426.1 - 0.0069 16.0 0.5 4.2 7.0 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EEQ75426.1 - 0.007 15.9 0.5 0.53 9.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EEQ75426.1 - 0.01 15.2 0.1 0.57 9.5 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.12 EEQ75426.1 - 0.016 14.7 0.5 3.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.10 EEQ75426.1 - 0.018 14.7 0.7 7 6.3 0.1 3.0 3 0 0 3 3 3 0 NTPase PduV-EutP PF10662.4 EEQ75426.1 - 0.02 14.3 0.5 4.4 6.7 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.7 EEQ75426.1 - 0.044 12.8 1.0 2.6 7.0 0.2 2.4 2 0 0 2 2 2 0 Zeta toxin KAP_NTPase PF07693.9 EEQ75426.1 - 0.044 12.7 0.0 3 6.7 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain Telomere_Sde2 PF13019.1 EEQ75426.1 - 0.047 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Telomere stability and silencing PRK PF00485.13 EEQ75426.1 - 0.062 12.8 1.4 2.1 7.8 0.1 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family PDR_assoc PF08370.6 EEQ75426.1 - 0.064 12.7 0.2 0.064 12.7 0.1 2.1 2 0 0 2 2 1 0 Plant PDR ABC transporter associated ABC_ATPase PF09818.4 EEQ75426.1 - 0.072 11.6 0.0 0.16 10.5 0.0 1.5 2 0 0 2 2 1 0 Predicted ATPase of the ABC class KaiC PF06745.8 EEQ75426.1 - 0.091 11.8 1.2 9.8 5.2 0.1 3.0 3 0 0 3 3 3 0 KaiC SRPRB PF09439.5 EEQ75426.1 - 0.11 11.7 0.6 11 5.1 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF2075 PF09848.4 EEQ75426.1 - 0.21 10.4 0.2 7.6 5.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_35 PF14516.1 EEQ75426.1 - 0.25 9.9 0.1 11 4.4 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain Gtr1_RagA PF04670.7 EEQ75426.1 - 0.33 10.0 0.6 15 4.6 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Dynamin_N PF00350.18 EEQ75426.1 - 3.9 7.2 4.9 1.4 8.6 0.2 2.3 3 0 0 3 3 2 0 Dynamin family Bys1 PF04681.7 EEQ75428.1 - 8.2e-11 41.8 1.3 1.5e-10 40.9 0.9 1.4 1 1 0 1 1 1 1 Blastomyces yeast-phase-specific protein Thaumatin PF00314.12 EEQ75428.1 - 5.9e-06 25.9 4.0 0.002 17.5 0.1 2.8 1 1 2 3 3 3 2 Thaumatin family Sec23_trunk PF04811.10 EEQ75429.1 - 1.5e-52 178.4 0.0 4.4e-52 176.8 0.0 1.7 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EEQ75429.1 - 1.3e-23 82.3 0.0 2.2e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EEQ75429.1 - 3.4e-20 72.3 0.1 4.2e-19 68.8 0.0 2.3 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EEQ75429.1 - 4.4e-17 61.3 5.9 1e-16 60.2 4.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EEQ75429.1 - 1.7e-07 30.7 0.0 3.5e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat AA_permease_2 PF13520.1 EEQ75430.1 - 1.1e-40 139.4 38.8 1.1e-39 136.1 15.8 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 EEQ75430.1 - 9.2e-13 47.3 30.9 6e-11 41.3 14.6 2.1 1 1 1 2 2 2 2 Amino acid permease Peptidase_M56 PF05569.6 EEQ75430.1 - 0.08 11.8 2.0 0.19 10.6 1.4 1.6 1 0 0 1 1 1 0 BlaR1 peptidase M56 CPSF100_C PF13299.1 EEQ75433.1 - 1.3e-44 152.1 0.0 2.8e-44 151.1 0.0 1.6 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EEQ75433.1 - 1.1e-26 93.2 0.0 2.6e-26 91.9 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 EEQ75433.1 - 1.6e-06 27.8 0.0 3.5e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase PGM_PMM_IV PF00408.15 EEQ75433.1 - 0.056 13.4 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain zf-H2C2_2 PF13465.1 EEQ75435.1 - 6.5e-06 26.1 4.0 6.5e-06 26.1 2.8 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 EEQ75435.1 - 2.7e-05 24.2 11.4 0.011 16.0 0.9 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ75435.1 - 8.7e-05 22.5 12.4 0.016 15.5 1.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger COG5 PF10392.4 EEQ75437.1 - 2e-42 144.2 0.2 5.4e-41 139.6 0.0 2.9 3 0 0 3 3 3 1 Golgi transport complex subunit 5 DUF883 PF05957.8 EEQ75437.1 - 1.9 8.9 6.0 4 7.9 1.0 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) SYS1 PF09801.4 EEQ75438.1 - 1.3e-53 180.8 9.7 1.5e-53 180.6 6.7 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF485 PF04341.7 EEQ75438.1 - 0.021 14.5 3.0 0.021 14.5 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF485 TSP9 PF11493.3 EEQ75438.1 - 0.18 12.3 2.6 0.31 11.6 1.8 1.3 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 COX6B PF02297.12 EEQ75439.1 - 5.4e-22 77.5 2.0 6.6e-22 77.3 1.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb RRM_1 PF00076.17 EEQ75440.1 - 5.7e-07 29.0 0.0 1.1e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ75440.1 - 5e-05 23.1 0.0 0.00013 21.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ75440.1 - 0.0027 17.5 0.1 0.0065 16.2 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RF-1 PF00472.15 EEQ75441.1 - 3.1e-15 55.9 1.3 4.8e-15 55.3 0.9 1.3 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.4 EEQ75441.1 - 0.00058 19.9 0.1 0.00086 19.3 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein U3_assoc_6 PF08640.6 EEQ75442.1 - 2.4e-29 100.9 0.9 3.2e-28 97.3 0.2 2.3 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 EEQ75442.1 - 0.0028 18.1 0.2 0.69 10.7 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 EEQ75442.1 - 0.0057 15.7 0.3 0.009 15.1 0.2 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EEQ75442.1 - 0.05 12.4 0.1 0.076 11.8 0.1 1.4 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Frag1 PF10277.4 EEQ75443.1 - 3.4e-42 144.3 6.6 3.4e-42 144.3 4.6 2.2 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family AIF-MLS PF14962.1 EEQ75444.1 - 0.0074 15.9 0.5 0.0088 15.7 0.4 1.0 1 0 0 1 1 1 1 Mitochondria Localisation Sequence Apolipoprotein PF01442.13 EEQ75444.1 - 0.012 15.1 0.9 0.012 15.1 0.1 1.3 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF1476 PF07345.6 EEQ75444.1 - 0.014 15.6 2.0 0.02 15.1 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1476) Host_attach PF10116.4 EEQ75444.1 - 0.017 15.3 0.7 0.021 15.0 0.5 1.2 1 0 0 1 1 1 0 Protein required for attachment to host cells DUF948 PF06103.6 EEQ75444.1 - 0.074 12.9 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) TEX12 PF15219.1 EEQ75444.1 - 0.086 12.8 0.2 0.13 12.2 0.2 1.2 1 0 0 1 1 1 0 Testis-expressed 12 bZIP_C PF12498.3 EEQ75445.1 - 0.9 10.7 5.7 1.1 10.5 1.9 2.4 2 0 0 2 2 2 0 Basic leucine-zipper C terminal MutS_V PF00488.16 EEQ75446.1 - 2.9e-95 318.1 0.0 4.6e-95 317.4 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EEQ75446.1 - 1.5e-39 135.9 0.4 1.5e-39 135.9 0.3 1.7 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 EEQ75446.1 - 1.8e-18 66.9 0.1 5e-18 65.4 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EEQ75446.1 - 4.4e-16 58.8 1.6 1e-15 57.6 0.4 2.3 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.15 EEQ75446.1 - 4.9e-14 52.3 0.0 2.9e-13 49.8 0.0 2.2 2 0 0 2 2 2 1 MutS domain I IF-2 PF11987.3 EEQ75446.1 - 0.092 12.6 0.0 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 Translation-initiation factor 2 Gpi1 PF05024.10 EEQ75447.1 - 6.7e-63 211.7 10.4 1.3e-62 210.8 7.2 1.5 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Myb_DNA-bind_6 PF13921.1 EEQ75448.1 - 0.00048 20.1 0.0 0.0008 19.4 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEQ75448.1 - 0.00052 20.0 0.2 0.0038 17.2 0.1 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain UPF0203 PF05254.7 EEQ75449.1 - 2.1e-28 97.9 2.6 2.4e-28 97.7 1.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 EEQ75449.1 - 0.0024 17.6 4.4 0.079 12.7 0.2 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 EEQ75449.1 - 0.037 14.0 3.8 0.37 10.8 2.9 2.0 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) UCR_hinge PF02320.11 EEQ75449.1 - 0.049 13.5 4.1 0.15 12.0 2.9 1.7 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein DUF3456 PF11938.3 EEQ75449.1 - 0.07 13.1 1.0 0.11 12.4 0.5 1.4 1 1 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP DUF1903 PF08991.5 EEQ75449.1 - 0.62 10.2 4.1 2.7 8.1 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1903) COX6B PF02297.12 EEQ75449.1 - 0.69 9.9 6.6 1.2 9.2 0.3 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DNA_pol_A_exo1 PF01612.15 EEQ75450.1 - 3.7e-40 137.2 0.3 1.7e-39 135.1 0.2 2.0 2 0 0 2 2 2 1 3'-5' exonuclease PMC2NT PF08066.7 EEQ75450.1 - 2.7e-25 88.4 0.2 2.7e-25 88.4 0.2 2.7 4 0 0 4 4 4 1 PMC2NT (NUC016) domain HRDC PF00570.18 EEQ75450.1 - 4.2e-12 45.5 0.1 1.5e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 HRDC domain U79_P34 PF03064.11 EEQ75451.1 - 2.4 7.6 9.4 3.3 7.1 6.5 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RasGAP PF00616.14 EEQ75452.1 - 8.6e-55 185.4 0.3 8.6e-55 185.4 0.2 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EEQ75452.1 - 1.3e-32 112.4 4.6 1.3e-32 112.4 3.2 2.6 3 0 0 3 3 3 1 RasGAP C-terminus CRAL_TRIO PF00650.15 EEQ75453.1 - 1.2e-36 125.5 0.0 1.9e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EEQ75453.1 - 1.8e-10 40.8 0.5 7e-10 38.8 0.1 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EEQ75453.1 - 1.3e-05 25.0 0.0 4.3e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Mis14 PF08641.7 EEQ75454.1 - 1.9e-21 76.5 1.0 1.7e-20 73.5 0.3 2.5 2 1 1 3 3 3 1 Kinetochore protein Mis14 like DUF4110 PF13422.1 EEQ75454.1 - 0.025 14.3 0.5 0.052 13.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) PPR_3 PF13812.1 EEQ75456.1 - 4.1e-06 26.6 0.0 5.4e-05 23.1 0.0 2.9 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 EEQ75456.1 - 1.2e-05 25.1 0.1 0.0054 16.6 0.0 2.6 2 0 0 2 2 2 2 PPR repeat family KH_1 PF00013.24 EEQ75456.1 - 0.00099 18.7 0.0 0.0022 17.6 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EEQ75456.1 - 0.04 13.5 0.0 0.087 12.5 0.0 1.6 1 0 0 1 1 1 0 KH domain PPR PF01535.15 EEQ75456.1 - 0.078 12.9 0.0 0.33 11.0 0.0 2.2 1 0 0 1 1 1 0 PPR repeat Acetyltransf_1 PF00583.19 EEQ75457.1 - 4.8e-18 64.9 0.0 7.2e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ75457.1 - 3.2e-11 43.2 0.0 5.7e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEQ75457.1 - 1e-10 41.2 0.0 1.7e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EEQ75457.1 - 1.9e-10 40.8 0.0 2.6e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEQ75457.1 - 7.4e-10 39.1 0.0 9.5e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EEQ75457.1 - 1.8e-06 27.9 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEQ75457.1 - 2.8e-05 23.9 0.1 5.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EEQ75457.1 - 0.00037 20.4 0.0 0.00052 20.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.2 EEQ75457.1 - 0.00046 19.0 0.7 0.0006 18.7 0.1 1.4 2 0 0 2 2 2 1 GNAT acetyltransferase Acetyltransf_CG PF14542.1 EEQ75457.1 - 0.0028 17.5 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase LCAT PF02450.10 EEQ75458.1 - 1.7e-90 303.8 0.0 2e-90 303.5 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 EEQ75458.1 - 0.01 15.1 0.0 0.028 13.7 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 2) Abhydrolase_6 PF12697.2 EEQ75458.1 - 0.038 13.8 0.0 0.07 13.0 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EEQ75458.1 - 0.074 12.6 0.1 0.16 11.5 0.1 1.6 1 1 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.7 EEQ75458.1 - 0.083 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 EEQ75458.1 - 0.084 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2305 PF10230.4 EEQ75458.1 - 0.092 12.1 0.3 0.43 9.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) PAP2 PF01569.16 EEQ75460.1 - 3.3e-12 46.1 6.3 3.3e-12 46.1 4.4 2.2 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EEQ75460.1 - 6.8e-07 28.9 4.4 2.4e-06 27.2 3.1 1.9 1 1 0 1 1 1 1 PAP2 superfamily Tic20 PF09685.5 EEQ75461.1 - 0.84 9.6 5.3 0.19 11.7 0.6 2.0 2 0 0 2 2 2 0 Tic20-like protein Pkinase PF00069.20 EEQ75464.1 - 1.8e-09 37.1 0.0 2.4e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ75464.1 - 0.0002 20.5 0.0 0.0012 18.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Sugar_tr PF00083.19 EEQ75465.1 - 6.1e-31 107.4 26.1 8.7e-30 103.6 18.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ75465.1 - 7.5e-31 107.1 30.7 6.5e-25 87.5 10.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4330 PF14221.1 EEQ75466.1 - 0.012 15.4 0.2 0.015 15.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) Wzy_C PF04932.10 EEQ75466.1 - 0.013 15.3 0.2 0.017 14.9 0.1 1.1 1 0 0 1 1 1 0 O-Antigen ligase MacB_PCD PF12704.2 EEQ75466.1 - 0.021 14.4 0.0 0.022 14.3 0.0 1.1 1 0 0 1 1 1 0 MacB-like periplasmic core domain DUF3951 PF13131.1 EEQ75466.1 - 0.041 13.6 1.2 0.059 13.1 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) Choline_transpo PF04515.7 EEQ75466.1 - 0.084 11.5 0.0 0.091 11.4 0.0 1.0 1 0 0 1 1 1 0 Plasma-membrane choline transporter EphA2_TM PF14575.1 EEQ75466.1 - 0.09 13.1 0.1 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3139 PF11337.3 EEQ75466.1 - 0.18 12.1 1.3 0.24 11.6 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) S1FA PF04689.8 EEQ75466.1 - 0.65 9.9 3.1 0.98 9.3 2.1 1.5 1 1 0 1 1 1 0 DNA binding protein S1FA DUF1768 PF08719.6 EEQ75467.1 - 4.9e-41 140.0 0.1 2.6e-38 131.2 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF1768) HNH_2 PF13391.1 EEQ75468.1 - 0.0054 16.4 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease DnaJ PF00226.26 EEQ75470.1 - 2.7e-19 68.6 0.0 6.4e-19 67.4 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain DUF4407 PF14362.1 EEQ75470.1 - 0.022 13.7 7.4 0.029 13.3 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4355 PF14265.1 EEQ75470.1 - 0.041 13.8 16.1 0.069 13.1 11.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) CCDC71L PF15374.1 EEQ75470.1 - 0.16 11.2 4.5 0.2 10.9 3.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L APG6 PF04111.7 EEQ75470.1 - 0.88 8.5 11.4 1.2 8.1 7.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Peptidase_S49_N PF08496.5 EEQ75470.1 - 3 7.5 6.8 4.5 7.0 4.7 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Borrelia_P83 PF05262.6 EEQ75470.1 - 5.1 5.2 11.5 6.6 4.8 8.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Cation_efflux PF01545.16 EEQ75471.1 - 4.4e-65 219.5 4.7 5.7e-65 219.2 3.2 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 EEQ75471.1 - 4.3e-07 29.2 5.5 6.9e-07 28.5 3.8 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2976 PF11190.3 EEQ75471.1 - 0.025 14.1 0.6 0.025 14.1 0.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) DUF2370 PF10176.4 EEQ75471.1 - 0.04 13.2 0.0 7.9 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) DUF2776 PF10951.3 EEQ75471.1 - 0.045 12.8 0.6 0.26 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2776) BPD_transp_2 PF02653.11 EEQ75471.1 - 2.7 6.8 8.1 0.083 11.8 0.5 2.1 2 1 0 2 2 2 0 Branched-chain amino acid transport system / permease component Pkinase PF00069.20 EEQ75472.1 - 4.1e-18 65.4 0.0 3.6e-15 55.8 0.0 2.8 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ75472.1 - 2.6e-05 23.4 0.0 0.0067 15.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase 2OG-FeII_Oxy_3 PF13640.1 EEQ75474.1 - 8.3e-10 39.0 0.0 1.4e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EEQ75474.1 - 2.7e-06 26.9 0.0 4.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3530 PF12048.3 EEQ75474.1 - 0.029 13.3 0.1 0.044 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) ERF PF04404.7 EEQ75474.1 - 1.9 7.9 4.5 3.4 7.1 3.1 1.3 1 0 0 1 1 1 0 ERF superfamily cNMP_binding PF00027.24 EEQ75475.1 - 2.3e-41 139.5 0.0 2.1e-21 75.5 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Fork_head PF00250.13 EEQ75479.1 - 5.4e-17 61.6 0.0 1.1e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EEQ75479.1 - 0.0002 21.4 0.0 0.00053 20.0 0.0 1.7 1 0 0 1 1 1 1 FHA domain Snf7 PF03357.16 EEQ75480.1 - 6.3e-34 116.8 17.0 6.3e-34 116.8 11.8 2.0 2 0 0 2 2 2 1 Snf7 PTSIIB_sorb PF03830.10 EEQ75480.1 - 0.011 15.5 2.3 0.018 14.9 1.6 1.3 1 0 0 1 1 1 0 PTS system sorbose subfamily IIB component Peptidase_S46 PF10459.4 EEQ75480.1 - 0.094 11.1 8.9 0.11 10.9 6.2 1.1 1 0 0 1 1 1 0 Peptidase S46 PPP5 PF08321.7 EEQ75480.1 - 0.37 10.8 3.3 2 8.5 2.2 2.1 1 1 1 2 2 2 0 PPP5 TPR repeat region ABA_WDS PF02496.11 EEQ75480.1 - 1.2 9.4 5.8 1.2 9.3 0.1 3.0 3 1 0 3 3 3 0 ABA/WDS induced protein MutS_III PF05192.13 EEQ75480.1 - 1.7 8.4 5.4 1.8 8.3 3.4 1.3 1 1 0 1 1 1 0 MutS domain III DUF3138 PF11336.3 EEQ75480.1 - 2.3 6.3 8.9 1.2 7.2 4.7 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) BLOC1_2 PF10046.4 EEQ75480.1 - 6.8 6.9 13.6 2.5 8.2 5.0 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ribosomal_60s PF00428.14 EEQ75480.1 - 9.3 6.7 12.3 0.49 10.8 2.4 2.8 2 1 1 3 3 3 0 60s Acidic ribosomal protein Ten1 PF12658.2 EEQ75481.1 - 1.1e-28 99.5 0.0 1.3e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Dicty_REP PF05086.7 EEQ75481.1 - 0.0037 15.1 2.6 0.0039 15.0 1.8 1.0 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Tir_receptor_C PF07489.6 EEQ75481.1 - 0.0045 16.7 6.0 0.0053 16.5 4.2 1.1 1 0 0 1 1 1 1 Translocated intimin receptor (Tir) C-terminus DUF3439 PF11921.3 EEQ75481.1 - 0.0059 16.3 5.0 0.0082 15.8 3.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) SSP160 PF06933.6 EEQ75481.1 - 0.044 11.7 6.0 0.049 11.6 4.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 gpUL132 PF11359.3 EEQ75481.1 - 8.9 5.5 9.9 12 5.1 6.9 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 MFS_1 PF07690.11 EEQ75482.1 - 6.8e-40 136.8 29.6 6.8e-40 136.8 20.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ75482.1 - 4.4e-13 48.6 9.8 4.4e-13 48.6 6.8 1.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EEQ75482.1 - 3.9e-07 28.6 2.8 3.9e-07 28.6 1.9 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EEQ75482.1 - 0.026 12.6 7.0 0.16 10.0 4.8 2.0 1 1 0 1 1 1 0 Transmembrane secretion effector Corona_S2 PF01601.11 EEQ75482.1 - 0.46 8.5 1.9 0.69 7.9 1.3 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Kelch_5 PF13854.1 EEQ75483.1 - 2.3e-17 62.5 7.0 2e-08 33.9 0.1 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 EEQ75483.1 - 5.7e-11 42.0 3.2 0.011 15.4 0.1 6.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EEQ75483.1 - 8.5e-10 38.3 11.2 0.00063 19.8 0.2 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 EEQ75483.1 - 9.3e-08 31.5 3.7 0.042 13.6 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 EEQ75483.1 - 1.4e-06 28.2 6.6 0.0085 16.2 0.0 5.3 5 0 0 5 5 5 1 Galactose oxidase, central domain SKG6 PF08693.5 EEQ75483.1 - 4.6e-06 25.8 2.6 1.1e-05 24.5 1.8 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_1 PF01344.20 EEQ75483.1 - 0.0014 18.1 4.3 0.76 9.3 0.1 3.7 4 0 0 4 4 4 2 Kelch motif BCAS2 PF05700.6 EEQ75484.1 - 7.4e-54 182.5 0.5 8.8e-54 182.3 0.3 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF4206 PF13901.1 EEQ75484.1 - 0.14 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) Ceramidase_alk PF04734.8 EEQ75485.1 - 1.2e-274 912.3 0.0 1.4e-274 912.1 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase EI24 PF07264.6 EEQ75486.1 - 0.0014 18.0 19.6 0.011 15.1 13.6 2.1 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) HAD_2 PF13419.1 EEQ75487.1 - 2.3e-32 112.5 0.0 2.8e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ75487.1 - 0.0042 16.7 0.0 0.0085 15.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HNH PF01844.18 EEQ75488.1 - 0.018 14.9 1.3 0.04 13.8 0.9 1.6 1 1 0 1 1 1 0 HNH endonuclease GTP_EFTU PF00009.22 EEQ75490.1 - 4e-37 127.4 7.7 7.6e-37 126.5 3.2 2.8 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EEQ75490.1 - 1.2e-26 92.7 0.1 4.9e-26 90.7 0.1 2.1 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EEQ75490.1 - 4.4e-12 45.9 6.3 1.9e-07 31.1 0.3 3.3 3 0 0 3 3 3 2 Elongation factor Tu domain 2 IF2_N PF04760.10 EEQ75490.1 - 8.4e-11 41.3 0.0 2.1e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 EEQ75490.1 - 2.1e-07 30.9 0.1 5.1e-07 29.6 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEQ75490.1 - 4.2e-05 24.0 0.1 0.00011 22.6 0.1 1.8 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ75490.1 - 0.00022 20.5 0.0 0.00043 19.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EEQ75490.1 - 0.00041 19.6 1.7 0.0012 18.1 0.0 2.3 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit zf-RanBP PF00641.13 EEQ75490.1 - 0.00081 18.4 1.9 0.0017 17.4 1.3 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others PduV-EutP PF10662.4 EEQ75490.1 - 0.0022 17.4 0.2 0.0075 15.7 0.1 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EEQ75490.1 - 0.017 14.3 0.8 0.056 12.7 0.6 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B DZR PF12773.2 EEQ75490.1 - 0.022 14.5 1.5 0.047 13.5 1.0 1.5 1 0 0 1 1 1 0 Double zinc ribbon Ras PF00071.17 EEQ75490.1 - 0.028 13.8 0.1 0.058 12.7 0.1 1.5 1 0 0 1 1 1 0 Ras family zf-Sec23_Sec24 PF04810.10 EEQ75490.1 - 0.12 11.9 2.1 0.1 12.1 0.2 1.8 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger zf-ribbon_3 PF13248.1 EEQ75490.1 - 0.23 10.7 2.3 0.45 9.7 1.6 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Dynamin_N PF00350.18 EEQ75490.1 - 0.93 9.2 7.4 7.9 6.2 0.0 3.5 3 1 1 4 4 4 0 Dynamin family mono-CXXC PF15626.1 EEQ75490.1 - 2.2 8.2 9.6 0.29 11.1 2.8 2.4 2 0 0 2 2 2 0 single CXXC unit Mito_carr PF00153.22 EEQ75491.1 - 2.4e-64 213.0 1.2 5.2e-21 74.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyoxalase_2 PF12681.2 EEQ75492.1 - 4.8e-07 30.3 0.0 5.9e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Ribosomal_S2 PF00318.15 EEQ75493.1 - 4.3e-51 173.1 0.0 6.3e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S2 Rick_17kDa_Anti PF05433.10 EEQ75494.1 - 0.00013 21.5 12.3 0.00013 21.5 8.5 2.9 3 1 0 3 3 3 1 Glycine zipper 2TM domain TraT PF05818.7 EEQ75494.1 - 0.04 13.3 0.1 0.06 12.7 0.1 1.4 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF605 PF04652.11 EEQ75494.1 - 0.17 11.2 6.9 0.16 11.3 4.8 1.1 1 0 0 1 1 1 0 Vta1 like DUF1183 PF06682.7 EEQ75494.1 - 2 7.9 25.6 0.34 10.4 15.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) F-box-like PF12937.2 EEQ75495.1 - 0.014 15.1 0.5 0.014 15.1 0.3 1.9 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 EEQ75495.1 - 0.025 14.2 1.4 0.043 13.4 0.2 2.0 2 0 0 2 2 2 0 F-box domain SURF6 PF04935.7 EEQ75496.1 - 4.3e-54 183.0 34.9 4.3e-54 183.0 24.2 4.7 3 1 1 4 4 4 1 Surfeit locus protein 6 RRP14 PF15459.1 EEQ75496.1 - 2.9e-23 81.6 1.0 2.9e-23 81.6 0.7 8.5 7 3 1 8 8 8 1 60S ribosome biogenesis protein Rrp14 Fer4 PF00037.22 EEQ75497.1 - 5e-13 48.0 16.2 5.7e-08 32.0 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EEQ75497.1 - 1.5e-11 44.4 9.3 2.3e-11 43.8 6.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EEQ75497.1 - 4.3e-09 36.5 8.8 7.6e-09 35.7 6.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EEQ75497.1 - 5.9e-09 35.5 10.0 1.4e-08 34.3 7.0 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EEQ75497.1 - 7.1e-09 36.2 6.5 0.00022 21.9 0.3 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.1 EEQ75497.1 - 3.6e-08 33.3 19.5 4.9e-06 26.4 7.2 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 EEQ75497.1 - 1.4e-07 31.0 14.7 0.00046 19.9 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.1 EEQ75497.1 - 2.9e-07 30.2 31.6 0.0001 22.0 8.6 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.2 EEQ75497.1 - 1.8e-06 27.8 10.2 0.0003 20.8 0.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EEQ75497.1 - 2.8e-06 26.9 16.4 0.0028 17.4 2.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EEQ75497.1 - 6.8e-06 26.3 9.1 0.00044 20.5 7.1 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 EEQ75497.1 - 8.2e-05 22.9 9.5 0.027 14.8 0.5 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EEQ75497.1 - 0.0039 17.5 14.6 0.14 12.5 2.9 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EEQ75497.1 - 0.014 15.8 13.0 0.22 12.0 1.2 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 EEQ75497.1 - 0.12 12.9 16.1 0.17 12.5 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EEQ75497.1 - 0.76 9.9 4.9 1.2 9.3 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain PP-binding PF00550.20 EEQ75498.1 - 8e-11 42.0 0.3 1.2e-10 41.5 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EEQ75498.1 - 6.7e-06 26.0 0.1 9.5e-06 25.5 0.1 1.1 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EEQ75498.1 - 0.031 14.3 0.1 0.045 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Ribosomal_S30AE PF02482.14 EEQ75498.1 - 0.07 13.5 0.1 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein GPP34 PF05719.6 EEQ75499.1 - 2.8e-63 213.6 0.1 3.6e-63 213.3 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) DUF2183 PF09949.4 EEQ75500.1 - 5.5e-33 112.8 0.0 1.1e-32 111.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) adh_short PF00106.20 EEQ75501.1 - 3.7e-11 43.2 0.0 7e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ75501.1 - 1.6e-05 24.6 0.0 2.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 EEQ75501.1 - 0.015 14.3 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Peripla_BP_4 PF13407.1 EEQ75501.1 - 0.033 13.5 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain Shikimate_DH PF01488.15 EEQ75501.1 - 0.035 14.2 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.1 EEQ75501.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EEQ75501.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 2 0 0 2 2 2 0 NADH(P)-binding Phytase PF02333.10 EEQ75503.1 - 2.8e-56 190.9 0.1 6.5e-53 179.8 0.0 2.3 2 0 0 2 2 2 2 Phytase EGF_2 PF07974.8 EEQ75503.1 - 0.0031 17.6 13.2 0.0031 17.6 9.1 2.5 2 0 0 2 2 2 1 EGF-like domain EGF_alliinase PF04863.8 EEQ75503.1 - 4.8 7.2 10.7 0.67 9.9 3.2 2.5 3 0 0 3 3 3 0 Alliinase EGF-like domain PBP1_TM PF14812.1 EEQ75504.1 - 0.069 13.4 1.8 0.074 13.3 0.0 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Vps54 PF07928.7 EEQ75505.1 - 0.16 12.0 0.6 0.72 9.9 0.1 2.1 2 0 0 2 2 2 0 Vps54-like protein CBS PF00571.23 EEQ75506.1 - 3.1e-22 78.0 1.9 6.7e-06 25.8 0.0 5.4 5 0 0 5 5 5 5 CBS domain Cnl2_NKP2 PF09447.5 EEQ75507.1 - 0.98 9.1 7.2 2.8 7.6 0.8 2.7 1 1 1 2 2 2 0 Cnl2/NKP2 family protein Macoilin PF09726.4 EEQ75507.1 - 3.7 5.7 12.3 5 5.2 8.5 1.1 1 0 0 1 1 1 0 Transmembrane protein VHS PF00790.14 EEQ75509.1 - 1.8e-46 157.3 0.1 5.2e-46 155.7 0.0 1.8 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EEQ75509.1 - 4.3e-26 90.8 2.4 1.3e-25 89.2 0.8 2.3 2 0 0 2 2 2 1 GAT domain Alpha_adaptinC2 PF02883.15 EEQ75509.1 - 5.1e-18 65.4 0.1 1.6e-17 63.8 0.1 1.9 1 0 0 1 1 1 1 Adaptin C-terminal domain DUF367 PF04034.8 EEQ75510.1 - 1.1e-47 160.8 0.1 1.5e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EEQ75510.1 - 2.9e-10 39.5 0.7 6.8e-10 38.3 0.5 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SnoaL PF07366.7 EEQ75510.1 - 0.021 14.4 0.1 0.039 13.5 0.0 1.5 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase COPI_C PF06957.6 EEQ75510.1 - 0.69 8.3 6.1 1.1 7.6 4.2 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus RNA_pol_Rpb1_5 PF04998.12 EEQ75511.1 - 0.54 9.4 2.3 0.64 9.2 1.6 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 zf-H2C2 PF09337.5 EEQ75512.1 - 7.4e-22 76.4 3.2 1.7e-21 75.2 2.2 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_4 PF13420.1 EEQ75512.1 - 0.0075 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEQ75512.1 - 0.0091 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EEQ75512.1 - 0.13 12.3 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Trypan_PARP PF05887.6 EEQ75512.1 - 5.9 6.7 10.1 1.9 8.2 3.0 2.0 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Cpn60_TCP1 PF00118.19 EEQ75513.1 - 2.7e-134 448.4 4.4 3.1e-134 448.2 3.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_C14 PF00656.17 EEQ75515.1 - 1.6e-70 237.6 0.0 2.2e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain F-box-like PF12937.2 EEQ75517.1 - 4.2e-06 26.3 0.4 1.3e-05 24.8 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ75517.1 - 0.0021 17.6 0.4 0.0074 15.9 0.0 2.1 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.1 EEQ75517.1 - 0.012 15.6 1.9 2.2 8.5 0.0 4.0 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.28 EEQ75517.1 - 0.23 11.6 1.7 27 5.2 0.1 3.7 2 0 0 2 2 2 0 Leucine Rich Repeat Ribosomal_S26e PF01283.14 EEQ75518.1 - 1.6e-50 170.1 8.3 1.9e-50 169.8 5.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Zn_ribbon_2 PF12674.2 EEQ75518.1 - 0.049 13.9 0.2 11 6.4 0.0 2.3 1 1 1 2 2 2 0 Putative zinc ribbon domain DUF2419 PF10343.4 EEQ75518.1 - 0.091 11.9 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2419) CBS PF00571.23 EEQ75519.1 - 1.7e-41 139.7 5.8 4.2e-11 42.4 0.0 5.0 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 EEQ75519.1 - 1e-09 37.9 0.1 3.6e-09 36.1 0.0 2.1 2 1 0 2 2 2 1 PB1 domain HEAT PF02985.17 EEQ75520.1 - 2.4e-21 73.8 8.6 0.001 18.9 0.0 11.2 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.1 EEQ75520.1 - 6.4e-21 74.4 8.5 2.2e-06 27.8 0.2 8.6 6 2 2 8 8 8 5 HEAT repeats HEAT_EZ PF13513.1 EEQ75520.1 - 7.6e-19 67.6 14.7 5.6e-07 29.8 0.2 10.2 10 1 1 11 11 10 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EEQ75520.1 - 8.5e-12 45.3 0.1 0.0067 16.7 0.0 6.3 3 2 3 6 6 6 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 EEQ75520.1 - 1.7e-07 30.3 0.5 0.0012 17.6 0.0 4.9 4 2 1 5 5 5 1 RNAPII transcription regulator C-terminal RIX1 PF08167.7 EEQ75520.1 - 4.6e-07 29.6 0.0 0.0011 18.6 0.0 4.8 4 2 1 5 5 5 1 rRNA processing/ribosome biogenesis Arm PF00514.18 EEQ75520.1 - 1.8e-06 27.5 0.3 0.37 10.6 0.0 4.5 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EEQ75520.1 - 2.1e-06 27.2 0.2 0.049 12.9 0.0 5.5 4 1 2 6 6 6 1 CLASP N terminal Adaptin_N PF01602.15 EEQ75520.1 - 8.8e-06 24.3 0.0 0.0031 15.9 0.0 3.5 3 1 1 4 4 4 1 Adaptin N terminal region IBN_N PF03810.14 EEQ75520.1 - 0.00023 20.9 0.2 0.0044 16.9 0.1 3.3 3 0 0 3 3 2 1 Importin-beta N-terminal domain TFCD_C PF12612.3 EEQ75520.1 - 0.0026 17.1 0.3 0.59 9.5 0.0 3.7 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal DUF3385 PF11865.3 EEQ75520.1 - 0.0043 16.9 0.0 15 5.4 0.0 4.7 4 1 0 4 4 4 0 Domain of unknown function (DUF3385) Proteasom_PSMB PF10508.4 EEQ75520.1 - 0.0054 15.0 0.5 0.05 11.8 0.0 2.7 2 1 1 3 3 3 1 Proteasome non-ATPase 26S subunit DUF4042 PF13251.1 EEQ75520.1 - 0.011 15.1 0.0 9.1 5.6 0.0 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF4042) V-ATPase_H_N PF03224.9 EEQ75520.1 - 0.013 14.6 1.2 0.75 8.8 0.0 3.2 3 0 0 3 3 3 0 V-ATPase subunit H DALR_1 PF05746.10 EEQ75520.1 - 0.15 12.0 3.6 1.8 8.5 0.3 3.9 4 0 0 4 4 4 0 DALR anticodon binding domain Aconitase PF00330.15 EEQ75521.1 - 4.8e-160 533.0 0.0 2e-159 531.0 0.0 1.8 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EEQ75521.1 - 1.4e-38 131.9 0.0 2.3e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF2408 PF10303.4 EEQ75522.1 - 2.3e-56 189.5 4.0 4.2e-33 114.3 0.0 5.2 2 2 3 5 5 5 4 Protein of unknown function (DUF2408) Spc7 PF08317.6 EEQ75522.1 - 0.011 14.3 0.6 0.032 12.8 0.4 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF869 PF05911.6 EEQ75522.1 - 0.031 12.5 1.4 0.046 11.9 1.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Spore_III_AB PF09548.5 EEQ75522.1 - 0.089 12.5 0.6 0.3 10.7 0.1 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Prefoldin PF02996.12 EEQ75522.1 - 0.1 12.2 0.9 8.1 6.1 0.0 2.7 1 1 1 2 2 2 0 Prefoldin subunit HR1 PF02185.11 EEQ75522.1 - 0.14 11.8 0.9 5.9 6.6 0.0 2.9 1 1 1 2 2 2 0 Hr1 repeat Prefoldin_2 PF01920.15 EEQ75522.1 - 0.25 11.1 3.3 7.8 6.3 0.1 3.2 1 1 2 3 3 3 0 Prefoldin subunit Ribosomal_60s PF00428.14 EEQ75523.1 - 7.9e-25 87.0 9.8 9.6e-25 86.8 6.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein GrpE PF01025.14 EEQ75523.1 - 0.069 12.7 0.9 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 GrpE PQ-loop PF04193.9 EEQ75524.1 - 1.2e-38 130.4 8.1 2.9e-20 71.5 0.2 2.6 2 0 0 2 2 2 2 PQ loop repeat DUF3278 PF11683.3 EEQ75524.1 - 0.065 13.2 0.4 0.16 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) BCD PF15461.1 EEQ75524.1 - 1.8 7.9 6.8 11 5.3 3.4 2.6 2 1 1 3 3 3 0 Beta-carotene 15,15'-dioxygenase APH PF01636.18 EEQ75525.1 - 1.2e-08 35.0 0.0 3.7e-08 33.4 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EEQ75525.1 - 0.00033 19.8 0.0 0.00048 19.3 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 EEQ75525.1 - 0.00059 19.4 0.0 0.0017 17.9 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EEQ75525.1 - 0.0083 14.8 0.0 0.014 14.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) PCIF1_WW PF12237.3 EEQ75526.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Phosphorylated CTD interacting factor 1 WW domain DUF737 PF05300.6 EEQ75527.1 - 0.057 13.3 1.8 0.066 13.1 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) VCX_VCY PF15231.1 EEQ75528.1 - 0.5 10.7 14.0 4.1 7.8 7.3 2.1 1 1 1 2 2 2 0 Variable charge X/Y family Tcf25 PF04910.9 EEQ75531.1 - 1e-85 287.8 0.0 1.7e-85 287.1 0.0 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Hamartin PF04388.7 EEQ75531.1 - 0.027 13.1 2.1 0.041 12.5 1.5 1.2 1 0 0 1 1 1 0 Hamartin protein TPR_14 PF13428.1 EEQ75531.1 - 0.088 13.4 0.6 40 5.2 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat PP2C PF00481.16 EEQ75532.1 - 6.5e-40 137.1 0.0 1.1e-39 136.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EEQ75532.1 - 0.00071 19.0 0.0 0.0021 17.5 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C 60KD_IMP PF02096.15 EEQ75533.1 - 3e-13 49.8 4.2 5.5e-13 49.0 2.9 1.4 1 1 0 1 1 1 1 60Kd inner membrane protein Glycos_transf_1 PF00534.15 EEQ75534.1 - 1.2e-18 67.0 0.0 2.1e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EEQ75534.1 - 2.2e-08 34.3 0.0 6.2e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 zf-H2C2_2 PF13465.1 EEQ75535.1 - 8.6e-14 51.0 9.5 5.5e-08 32.7 0.2 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EEQ75535.1 - 3.1e-12 46.0 13.6 8.8e-06 25.7 1.6 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ75535.1 - 1.2e-10 40.9 14.1 3.3e-05 23.9 1.8 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEQ75535.1 - 4.3e-06 26.7 6.4 0.077 13.1 0.2 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEQ75535.1 - 4e-05 23.6 2.6 0.01 16.0 0.2 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.1 EEQ75535.1 - 0.2 11.9 0.4 0.53 10.5 0.2 1.8 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2H2_6 PF13912.1 EEQ75535.1 - 0.25 11.3 7.9 4.9 7.2 0.4 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger Elf1 PF05129.8 EEQ75535.1 - 0.28 10.8 0.6 0.56 9.9 0.4 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like LIM PF00412.17 EEQ75535.1 - 0.42 10.7 3.2 3.9 7.6 2.3 2.3 1 1 1 2 2 2 0 LIM domain M20_dimer PF07687.9 EEQ75536.1 - 9.7e-15 54.2 0.0 2.3e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EEQ75536.1 - 9.4e-14 51.3 0.2 1.4e-13 50.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Pkinase PF00069.20 EEQ75537.1 - 1.4e-53 181.6 0.2 4.1e-37 127.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ75537.1 - 1.4e-26 93.1 0.0 1.4e-25 89.8 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ75537.1 - 2.3e-06 26.7 0.0 4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEQ75537.1 - 0.00042 20.1 0.0 0.005 16.5 0.0 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Nucleoplasmin PF03066.10 EEQ75537.1 - 0.99 8.9 6.1 6.1 6.3 3.6 2.3 2 0 0 2 2 2 0 Nucleoplasmin TPR_10 PF13374.1 EEQ75538.1 - 6.8e-09 35.3 0.0 1.4e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ75538.1 - 0.0013 18.6 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat Arch_ATPase PF01637.13 EEQ75538.1 - 0.034 13.8 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Orbi_VP6 PF01516.11 EEQ75538.1 - 0.077 12.0 0.1 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Orbivirus helicase VP6 FAM150 PF15129.1 EEQ75538.1 - 0.08 12.8 0.0 5.3 6.9 0.0 2.9 3 0 0 3 3 3 0 FAM150 family Kelch_4 PF13418.1 EEQ75539.1 - 0.0003 20.4 4.6 0.24 11.1 0.1 4.2 4 1 0 4 4 4 2 Galactose oxidase, central domain Mid2 PF04478.7 EEQ75539.1 - 0.00065 19.1 0.0 0.0019 17.5 0.0 1.8 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 EEQ75539.1 - 0.022 14.0 2.5 0.031 13.6 0.3 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Kelch_2 PF07646.10 EEQ75539.1 - 0.025 14.3 1.9 5.3 6.9 0.0 3.7 4 0 0 4 4 4 0 Kelch motif Kelch_5 PF13854.1 EEQ75539.1 - 0.051 13.5 0.1 1.3 9.0 0.0 3.2 4 0 0 4 4 4 0 Kelch motif PMP1_2 PF08114.6 EEQ75539.1 - 0.31 10.5 1.8 1.4 8.5 0.1 2.3 2 0 0 2 2 2 0 ATPase proteolipid family BPL_LplA_LipB PF03099.14 EEQ75540.1 - 4e-12 46.2 0.0 1e-11 44.8 0.0 1.8 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.16 EEQ75541.1 - 4.9e-130 433.0 0.0 5.8e-130 432.8 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Ima1_N PF09779.4 EEQ75542.1 - 4.4e-46 156.6 3.9 4.4e-46 156.6 2.7 2.3 2 0 0 2 2 2 1 Ima1 N-terminal domain RNHCP PF12647.2 EEQ75542.1 - 2.7 7.8 6.1 0.5 10.2 0.3 2.4 2 1 0 2 2 2 0 RNHCP domain Alg14 PF08660.6 EEQ75543.1 - 2.5e-47 161.0 0.0 6.9e-33 114.0 0.0 2.2 1 1 1 2 2 2 2 Oligosaccharide biosynthesis protein Alg14 like DUF3357 PF11837.3 EEQ75543.1 - 1.2 8.9 5.5 1.4 8.7 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF3357) PNK3P PF08645.6 EEQ75549.1 - 1.2e-54 184.1 0.0 2.1e-54 183.2 0.0 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EEQ75549.1 - 5.9e-34 116.9 0.0 2.7e-33 114.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 EEQ75549.1 - 3.1e-05 23.3 0.7 0.18 11.0 0.1 2.5 2 1 1 3 3 3 2 Chromatin associated protein KTI12 AAA_22 PF13401.1 EEQ75549.1 - 0.0026 17.8 0.0 0.0056 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain HAD_2 PF13419.1 EEQ75549.1 - 0.018 15.2 0.1 3.6 7.7 0.0 2.7 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Zeta_toxin PF06414.7 EEQ75549.1 - 0.033 13.3 0.0 0.097 11.7 0.0 1.8 1 1 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EEQ75549.1 - 0.052 14.3 0.0 0.12 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Med18 PF09637.5 EEQ75550.1 - 1.9e-57 194.6 0.0 2.2e-57 194.4 0.0 1.0 1 0 0 1 1 1 1 Med18 protein DUF2638 PF10937.3 EEQ75551.1 - 9.8e-40 136.0 0.2 1.1e-39 135.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) DUF647 PF04884.9 EEQ75552.1 - 6e-105 349.9 1.7 7.9e-105 349.5 1.2 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis RGS PF00615.14 EEQ75553.1 - 2.2e-14 53.5 0.0 3.4e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Pkinase PF00069.20 EEQ75557.1 - 7e-10 38.4 0.0 1.2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ75557.1 - 0.003 16.6 0.1 0.0048 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ75557.1 - 0.029 14.0 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family TPR_20 PF14561.1 EEQ75558.1 - 0.035 14.2 0.4 0.053 13.6 0.3 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat BMFP PF04380.8 EEQ75558.1 - 0.072 13.2 1.3 0.96 9.6 0.9 2.2 1 1 0 1 1 1 0 Membrane fusogenic activity RNase_H2-Ydr279 PF09468.5 EEQ75558.1 - 0.26 10.4 7.7 0.3 10.2 5.3 1.0 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) zf-FCS PF06467.9 EEQ75559.1 - 0.21 11.2 1.2 0.43 10.2 0.8 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif DUF3074 PF11274.3 EEQ75559.1 - 0.21 11.1 3.2 0.23 11.0 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) Aegerolysin PF06355.8 EEQ75561.1 - 2e-28 98.8 0.0 2.1e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Aegerolysin Pkinase PF00069.20 EEQ75563.1 - 5.4e-36 124.0 0.0 7.3e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ75563.1 - 2.4e-14 53.0 0.0 3.2e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ75563.1 - 0.0093 15.7 0.1 0.51 10.0 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Rtt106 PF08512.7 EEQ75564.1 - 1e-24 86.3 0.0 1.6e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Histone chaperone Rttp106-like KOW PF00467.24 EEQ75565.1 - 0.0029 17.2 0.9 0.0029 17.2 0.6 2.2 2 0 0 2 2 2 1 KOW motif Ras PF00071.17 EEQ75566.1 - 2e-55 186.6 0.0 2.3e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ75566.1 - 4.5e-15 56.2 0.0 6.8e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ75566.1 - 2.7e-06 26.7 0.0 4.4e-06 26.0 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EEQ75566.1 - 0.0016 17.6 0.0 0.0022 17.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EEQ75566.1 - 0.027 13.6 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF1712 PF08217.6 EEQ75567.1 - 0.048 11.9 0.6 1.1 7.4 0.0 3.0 3 1 0 3 3 3 0 Fungal domain of unknown function (DUF1712) Formyl_trans_N PF00551.14 EEQ75568.1 - 4.8e-23 81.6 0.0 9.7e-23 80.6 0.0 1.5 1 1 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 EEQ75568.1 - 0.00037 20.5 0.1 0.00087 19.3 0.0 1.7 1 1 0 1 1 1 1 Formyl transferase, C-terminal domain adh_short PF00106.20 EEQ75569.1 - 5.3e-30 104.5 0.2 7.2e-30 104.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ75569.1 - 2.6e-21 76.5 0.0 3.2e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ75569.1 - 5.9e-13 48.8 0.1 8.9e-13 48.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEQ75569.1 - 8.7e-05 22.0 0.2 0.00066 19.1 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family His_Phos_1 PF00300.17 EEQ75569.1 - 0.014 15.4 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) DUF4004 PF13171.1 EEQ75569.1 - 0.035 14.2 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4004) Cor1 PF04803.7 EEQ75569.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region NAD_binding_4 PF07993.7 EEQ75569.1 - 0.13 11.1 0.1 0.29 10.0 0.1 1.8 1 1 0 1 1 1 0 Male sterility protein Herpes_LMP2 PF07415.6 EEQ75570.1 - 0.47 8.9 4.1 0.78 8.2 2.9 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein EMP24_GP25L PF01105.19 EEQ75571.1 - 8e-52 175.6 0.0 1e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Myb_DNA-bind_6 PF13921.1 EEQ75572.1 - 0.0076 16.3 0.0 0.023 14.8 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Meth_synt_2 PF01717.13 EEQ75574.1 - 2.3e-144 480.3 0.0 1.7e-139 464.3 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EEQ75574.1 - 1.5e-118 395.6 0.0 8.1e-108 360.3 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Steroid_dh PF02544.11 EEQ75575.1 - 1.4e-12 47.6 2.2 8.8e-07 28.8 0.7 3.8 2 1 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EEQ75575.1 - 0.00078 18.8 0.0 0.0016 17.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Ufd2P_core PF10408.4 EEQ75576.1 - 1.5e-198 661.0 2.5 1.9e-198 660.7 1.7 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EEQ75576.1 - 3.7e-28 97.3 0.7 1.3e-27 95.5 0.5 2.1 1 0 0 1 1 1 1 U-box domain DUF1977 PF09320.6 EEQ75577.1 - 3.9e-28 97.8 0.0 6.2e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 EEQ75577.1 - 1.1e-24 85.8 0.2 1.9e-24 85.1 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain ADP_ribosyl_GH PF03747.9 EEQ75577.1 - 0.037 13.7 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase DUF2416 PF10315.4 EEQ75578.1 - 0.00015 21.9 0.1 0.00027 21.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) PMT PF02366.13 EEQ75578.1 - 0.006 15.9 0.3 0.0082 15.5 0.2 1.3 1 1 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF4536 PF15055.1 EEQ75578.1 - 0.031 14.3 0.2 0.4 10.7 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4536) CTP_transf_2 PF01467.21 EEQ75579.1 - 2.1e-05 24.5 0.0 6.7e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Cytidylyltransferase APH PF01636.18 EEQ75580.1 - 0.062 13.0 0.1 0.44 10.2 0.0 2.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family Ydc2-catalyt PF09159.5 EEQ75582.1 - 8.1e-101 337.1 0.6 9.9e-101 336.8 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 EEQ75582.1 - 2e-05 24.4 0.1 0.26 11.1 0.0 3.4 3 0 0 3 3 3 2 Poxvirus A22 protein SAP PF02037.22 EEQ75582.1 - 0.00017 20.9 1.1 0.0004 19.8 0.2 2.1 2 0 0 2 2 2 1 SAP domain Atrophin-1 PF03154.10 EEQ75582.1 - 0.057 11.5 0.6 0.083 11.0 0.4 1.2 1 0 0 1 1 1 0 Atrophin-1 family Trehalase PF01204.13 EEQ75583.1 - 7.5e-158 526.3 0.1 9.2e-158 526.0 0.1 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EEQ75583.1 - 1.2e-15 56.4 1.8 2e-15 55.7 1.3 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain CorA PF01544.13 EEQ75585.1 - 5.1e-11 42.1 2.5 7e-11 41.7 0.0 2.2 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein UBN2 PF14223.1 EEQ75587.1 - 0.025 14.3 0.0 0.025 14.3 0.0 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type SSP160 PF06933.6 EEQ75587.1 - 1.9 6.3 9.5 2.7 5.8 6.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Tcp11 PF05794.8 EEQ75589.1 - 2.6e-76 257.1 0.2 3.4e-76 256.7 0.1 1.1 1 0 0 1 1 1 1 T-complex protein 11 zf-DNL PF05180.7 EEQ75589.1 - 0.085 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 DNL zinc finger DUF2564 PF10819.3 EEQ75589.1 - 0.16 12.1 1.4 0.22 11.6 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) Peptidase_S10 PF00450.17 EEQ75592.1 - 7.3e-81 272.4 0.0 1.5e-80 271.4 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EEQ75592.1 - 0.12 12.1 0.0 18 5.1 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family SOG2 PF10428.4 EEQ75593.1 - 2.9e-102 342.6 0.1 2.9e-102 342.6 0.0 1.9 2 0 0 2 2 2 1 RAM signalling pathway protein LRR_4 PF12799.2 EEQ75593.1 - 1.1e-16 60.0 8.5 6.3e-08 32.0 2.1 3.7 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEQ75593.1 - 7.8e-14 51.1 6.8 4.8e-08 32.6 1.3 2.9 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EEQ75593.1 - 5.8e-10 37.7 9.2 0.0095 15.8 0.1 6.5 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EEQ75593.1 - 3.2e-06 26.4 10.1 6 7.5 0.0 6.5 6 0 0 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 EEQ75593.1 - 0.0017 18.2 6.0 4 7.8 0.1 5.4 4 1 1 5 5 5 1 Leucine Rich repeat LRR_5 PF13306.1 EEQ75593.1 - 0.091 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) MRP-S25 PF13741.1 EEQ75594.1 - 8.2e-87 290.4 3.2 9.5e-87 290.2 2.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 PPR_3 PF13812.1 EEQ75595.1 - 1.4e-12 46.8 1.3 0.092 13.0 0.0 6.6 7 0 0 7 7 7 4 Pentatricopeptide repeat domain PPR_2 PF13041.1 EEQ75595.1 - 1.2e-06 28.3 0.1 0.068 13.1 0.0 3.8 4 0 0 4 4 4 2 PPR repeat family PPR PF01535.15 EEQ75595.1 - 0.0045 16.8 5.0 1.3 9.1 0.0 5.0 6 0 0 6 6 6 2 PPR repeat Helicase_C PF00271.26 EEQ75596.1 - 3.3e-19 68.5 0.0 2.7e-15 55.9 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.24 EEQ75596.1 - 5.4e-16 58.5 0.0 4.2e-15 55.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase KH_1 PF00013.24 EEQ75597.1 - 2.8e-10 39.6 0.0 4.3e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EEQ75597.1 - 4.1e-06 26.3 0.8 0.00041 19.9 0.1 2.9 2 0 0 2 2 2 2 KH domain ALS_ss_C PF10369.4 EEQ75598.1 - 1.4e-19 69.5 0.0 3.1e-18 65.2 0.0 2.2 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 EEQ75598.1 - 5e-11 41.8 0.1 9.1e-11 41.0 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EEQ75598.1 - 4.9e-09 35.8 0.0 1.1e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 EEQ75598.1 - 0.015 15.0 0.1 5.6 6.7 0.0 2.5 2 0 0 2 2 2 0 ACT domain DUF3712 PF12505.3 EEQ75599.1 - 3.5e-08 33.5 3.1 6.8e-08 32.5 0.2 3.0 5 0 0 5 5 5 1 Protein of unknown function (DUF3712) LEA_2 PF03168.8 EEQ75599.1 - 0.0014 19.0 0.8 1.5 9.2 0.0 4.5 4 0 0 4 4 4 1 Late embryogenesis abundant protein OTCace_N PF02729.16 EEQ75600.1 - 9.3e-43 145.2 0.1 1.4e-42 144.6 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EEQ75600.1 - 1.1e-39 135.8 0.0 1.5e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Gp_dh_N PF00044.19 EEQ75600.1 - 0.068 13.1 0.1 6.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF3984 PF13136.1 EEQ75601.1 - 2.1e-104 349.2 33.9 1.3e-103 346.6 21.9 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3984) DUF2981 PF11200.3 EEQ75603.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) PBP1_TM PF14812.1 EEQ75604.1 - 0.16 12.3 4.0 0.24 11.7 2.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cut8_C PF08559.5 EEQ75605.1 - 4.4e-52 175.7 0.0 5.9e-52 175.3 0.0 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 EEQ75605.1 - 1.5e-15 56.6 0.6 4.4e-15 55.2 0.4 1.9 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 EEQ75605.1 - 2.3e-12 46.7 6.8 4.3e-12 45.8 4.7 1.5 1 0 0 1 1 1 1 Cut8 proteasome-binding domain rRNA_proc-arch PF13234.1 EEQ75606.1 - 3e-100 334.8 0.0 5.8e-100 333.8 0.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 EEQ75606.1 - 4.1e-66 221.6 1.5 9e-66 220.5 1.0 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EEQ75606.1 - 9.2e-22 77.3 0.2 2.5e-21 75.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ75606.1 - 3.9e-07 29.8 0.0 9.8e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ75606.1 - 0.014 15.2 0.0 0.11 12.2 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit T2SE PF00437.15 EEQ75606.1 - 0.093 11.6 0.0 0.2 10.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein COX7C PF02935.11 EEQ75607.1 - 1.3e-18 66.5 1.3 1.5e-18 66.2 0.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc IKI3 PF04762.7 EEQ75608.1 - 0 1102.3 0.0 0 1102.1 0.0 1.0 1 0 0 1 1 1 1 IKI3 family MutS_III PF05192.13 EEQ75608.1 - 0.059 13.1 0.7 0.13 12.0 0.2 1.8 2 0 0 2 2 2 0 MutS domain III TPR_16 PF13432.1 EEQ75608.1 - 0.59 10.8 4.6 0.5 11.1 0.3 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat GHMP_kinases_N PF00288.21 EEQ75609.1 - 6.3e-11 42.1 0.5 1.9e-10 40.6 0.3 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain Cyto_heme_lyase PF01265.12 EEQ75610.1 - 1.6e-76 257.3 1.6 1.4e-75 254.2 1.1 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Syntaxin_2 PF14523.1 EEQ75611.1 - 7.1e-24 83.7 2.3 7.1e-24 83.7 1.6 2.5 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EEQ75611.1 - 1.1e-16 60.2 1.9 3.6e-16 58.5 1.3 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 EEQ75611.1 - 0.0016 18.5 9.0 0.049 13.8 6.3 2.7 1 1 0 1 1 1 1 Syntaxin DUF883 PF05957.8 EEQ75611.1 - 0.32 11.3 0.1 0.32 11.3 0.1 3.3 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Synaptobrevin PF00957.16 EEQ75611.1 - 0.9 9.1 5.4 0.37 10.4 0.6 2.7 2 1 0 2 2 2 0 Synaptobrevin HisKA_3 PF07730.8 EEQ75611.1 - 2.5 8.5 8.4 5.2 7.4 0.0 3.7 3 1 1 4 4 4 0 Histidine kinase EspB PF05802.6 EEQ75611.1 - 5.2 5.9 7.6 0.79 8.6 0.3 2.3 3 0 0 3 3 3 0 Enterobacterial EspB protein Ndc1_Nup PF09531.5 EEQ75612.1 - 2.5e-132 442.3 10.5 6e-86 289.1 0.0 2.0 1 1 1 2 2 2 2 Nucleoporin protein Ndc1-Nup Y_phosphatase2 PF03162.8 EEQ75613.1 - 2e-33 115.0 0.0 3.1e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EEQ75613.1 - 2.6e-07 31.0 0.0 5.8e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 EEQ75613.1 - 0.00075 19.0 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EEQ75613.1 - 0.0041 16.4 0.0 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase TatD_DNase PF01026.16 EEQ75614.1 - 1.2e-46 158.9 0.0 1.5e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase FMN_dh PF01070.13 EEQ75615.1 - 1.3e-107 359.7 0.0 1.6e-107 359.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EEQ75615.1 - 4.9e-17 61.4 0.0 9.9e-17 60.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EEQ75615.1 - 1.1e-05 24.5 0.0 1.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EEQ75615.1 - 0.00043 19.2 0.0 0.0016 17.4 0.0 1.8 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EEQ75615.1 - 0.0043 16.2 0.1 0.011 14.8 0.0 1.6 1 1 1 2 2 2 1 Nitronate monooxygenase ThiG PF05690.9 EEQ75615.1 - 0.016 14.3 0.0 1.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 EEQ75615.1 - 0.16 10.9 0.0 0.84 8.5 0.0 1.9 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase PAE PF03283.8 EEQ75616.1 - 0.05 12.2 0.0 0.065 11.8 0.0 1.1 1 0 0 1 1 1 0 Pectinacetylesterase U79_P34 PF03064.11 EEQ75617.1 - 0.063 12.8 9.2 0.073 12.5 6.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 HMG_box_5 PF14887.1 EEQ75617.1 - 0.12 12.1 4.8 0.16 11.7 3.3 1.2 1 0 0 1 1 1 0 HMG (high mobility group) box 5 PNPase_C PF12111.3 EEQ75617.1 - 0.7 9.1 6.4 2.8 7.2 0.2 2.2 2 0 0 2 2 2 0 Polyribonucleotide phosphorylase C terminal Ribosomal_S8e PF01201.17 EEQ75619.1 - 8.2e-47 158.6 1.9 9.5e-47 158.4 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 EEQ75619.1 - 0.19 12.0 7.0 0.045 14.0 1.8 2.2 2 1 0 2 2 2 0 Small acidic protein family Metallophos PF00149.23 EEQ75620.1 - 1.2e-12 47.6 0.2 2.6e-12 46.5 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEQ75620.1 - 7.2e-09 35.6 0.0 1.1e-08 35.0 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pox_F17 PF04767.7 EEQ75621.1 - 0.1 12.8 0.2 0.17 12.1 0.2 1.4 1 0 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein Glyco_hydro_20 PF00728.17 EEQ75623.1 - 1.1e-99 333.9 0.1 1.5e-99 333.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EEQ75623.1 - 5.3e-22 78.8 0.0 9.6e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EEQ75623.1 - 1.4e-08 35.3 0.1 2.4e-08 34.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 BCS1_N PF08740.6 EEQ75624.1 - 0.0011 18.6 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal Vpu PF00558.14 EEQ75625.1 - 0.4 10.2 3.2 0.29 10.6 0.9 1.6 1 1 1 2 2 2 0 Vpu protein Cas_Cas6 PF01881.11 EEQ75625.1 - 1.1 9.4 4.3 1.3 9.2 3.0 1.1 1 0 0 1 1 1 0 CRISPR associated protein Cas6 MgtE PF01769.11 EEQ75626.1 - 0.0035 17.6 0.0 0.0052 17.0 0.0 1.3 1 0 0 1 1 1 1 Divalent cation transporter Ded_cyto PF06920.8 EEQ75628.1 - 3.5e-16 58.9 0.0 1e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 EEQ75628.1 - 4.4e-05 22.7 0.0 9.9e-05 21.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEQ75628.1 - 0.0013 18.2 0.0 0.015 14.8 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain Sec3_C PF09763.4 EEQ75629.1 - 2.9e-193 643.8 0.8 3.8e-193 643.4 0.5 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 EEQ75629.1 - 1.8e-30 104.6 0.9 5.2e-30 103.1 0.1 2.1 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH SRP40_C PF05022.7 EEQ75630.1 - 5.4e-22 78.0 0.1 5.4e-22 78.0 0.1 2.3 2 0 0 2 2 2 1 SRP40, C-terminal domain F-box PF00646.28 EEQ75631.1 - 4.9e-06 26.0 0.2 1e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EEQ75631.1 - 4.7e-05 23.0 0.1 9.1e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like Tox-MPTase3 PF15639.1 EEQ75631.1 - 0.14 11.8 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Metallopeptidase toxin 3 p450 PF00067.17 EEQ75632.1 - 3.8e-53 180.6 0.0 5.2e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1992 PF09350.5 EEQ75635.1 - 6.7e-24 83.5 0.2 2.1e-23 81.9 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) DUF1537 PF07005.6 EEQ75637.1 - 0.052 13.2 0.4 0.11 12.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF1537 DUF4578 PF15147.1 EEQ75637.1 - 0.11 12.8 0.2 0.27 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) Fzo_mitofusin PF04799.8 EEQ75639.1 - 0.0085 15.4 2.5 0.0098 15.2 1.7 1.2 1 0 0 1 1 1 1 fzo-like conserved region PEP-utilisers_N PF05524.8 EEQ75639.1 - 0.073 12.8 1.7 0.095 12.5 1.2 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF3399 PF11879.3 EEQ75639.1 - 1.1 9.5 5.8 0.34 11.1 2.2 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3399) HALZ PF02183.13 EEQ75641.1 - 5.8e-05 22.7 0.3 0.00022 20.8 0.1 2.0 2 0 0 2 2 2 1 Homeobox associated leucine zipper DUF904 PF06005.7 EEQ75641.1 - 0.0022 18.2 2.3 0.0034 17.6 0.2 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF904) bZIP_1 PF00170.16 EEQ75641.1 - 0.03 14.2 0.3 0.03 14.2 0.2 2.4 3 0 0 3 3 3 0 bZIP transcription factor Prefoldin PF02996.12 EEQ75641.1 - 0.038 13.6 1.2 0.038 13.6 0.8 2.3 3 0 0 3 3 3 0 Prefoldin subunit SIR2 PF02146.12 EEQ75641.1 - 0.13 11.9 0.1 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Sir2 family Kinesin-relat_1 PF12711.2 EEQ75641.1 - 0.13 12.6 1.9 0.17 12.2 0.2 2.1 2 0 0 2 2 2 0 Kinesin motor TBPIP PF07106.8 EEQ75641.1 - 0.32 10.5 3.9 3.1 7.3 0.3 2.7 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIC PF04977.10 EEQ75641.1 - 0.47 9.9 2.5 0.7 9.4 0.8 2.0 2 0 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 EEQ75641.1 - 1.8 8.9 4.9 4.3 7.7 0.3 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF972) DUF724 PF05266.9 EEQ75641.1 - 2.3 7.8 5.8 0.19 11.3 0.2 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF724) DUF1995 PF09353.5 EEQ75643.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1995) APH PF01636.18 EEQ75646.1 - 5e-11 42.7 3.3 6.6e-11 42.4 0.3 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EEQ75646.1 - 2.6e-06 26.3 0.0 3.3e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 EEQ75646.1 - 0.0003 20.0 0.0 0.00041 19.5 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 EEQ75646.1 - 0.0037 16.8 0.0 0.0056 16.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EEQ75646.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Homeobox PF00046.24 EEQ75646.1 - 0.11 12.1 0.0 0.95 9.1 0.0 2.3 2 0 0 2 2 2 0 Homeobox domain Pkinase PF00069.20 EEQ75648.1 - 3.7e-15 55.7 1.1 1.6e-13 50.4 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ75648.1 - 9e-09 34.7 0.0 1.4e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EEQ75648.1 - 5.6e-08 32.8 0.1 6.4e-06 26.0 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EEQ75648.1 - 2.6e-05 23.6 0.2 0.14 11.4 0.0 2.6 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.15 EEQ75648.1 - 5e-05 22.9 0.2 0.00062 19.3 0.0 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.9 EEQ75648.1 - 0.00017 20.7 0.3 0.00087 18.4 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 EEQ75648.1 - 0.063 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Kinase-like PF14531.1 EEQ75648.1 - 0.11 11.4 0.0 0.23 10.3 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Chromo PF00385.19 EEQ75649.1 - 8.1e-08 31.8 0.7 1.3e-07 31.1 0.5 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain KCl_Cotrans_1 PF03522.10 EEQ75649.1 - 6.1 6.4 6.9 2.4 7.7 0.3 2.6 3 0 0 3 3 3 0 K-Cl Co-transporter type 1 (KCC1) DUF3608 PF12257.3 EEQ75652.1 - 5e-76 255.2 0.0 9.3e-76 254.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EEQ75652.1 - 2.2e-29 101.0 1.0 4.5e-29 100.0 0.7 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Na_Ca_ex PF01699.19 EEQ75653.1 - 1.3e-41 141.4 34.7 4e-21 75.0 9.8 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Fungal_trans PF04082.13 EEQ75657.1 - 1.7e-25 89.3 0.1 3.6e-25 88.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ75657.1 - 9.6e-05 22.2 7.6 0.00017 21.4 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SH3_9 PF14604.1 EEQ75659.1 - 2.9e-07 29.9 0.3 6.9e-07 28.7 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEQ75659.1 - 0.00058 19.1 0.2 0.0012 18.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain DUF2668 PF10873.3 EEQ75659.1 - 0.023 14.8 0.1 0.023 14.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) Adeno_E3_CR2 PF02439.10 EEQ75659.1 - 0.1 12.1 0.4 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Pmp3 PF01679.12 EEQ75661.1 - 2.5e-17 62.3 7.6 3.2e-17 61.9 5.3 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator She9_MDM33 PF05546.6 EEQ75662.1 - 9e-93 309.5 7.7 9e-93 309.5 5.3 1.6 2 0 0 2 2 2 1 She9 / Mdm33 family PsbH PF00737.15 EEQ75662.1 - 0.028 13.9 1.0 0.028 13.9 0.7 2.0 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein UCR_TM PF02921.9 EEQ75663.1 - 7.7e-19 67.6 2.5 1.6e-18 66.6 1.7 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EEQ75663.1 - 5.7e-18 64.2 0.1 9.2e-18 63.6 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FeoB_C PF07664.7 EEQ75663.1 - 0.21 11.0 1.3 0.5 9.8 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus CBFD_NFYB_HMF PF00808.18 EEQ75664.1 - 1.7e-13 50.3 0.4 3e-13 49.6 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4584 PF15223.1 EEQ75664.1 - 0.00049 19.4 0.2 0.00064 19.0 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4584) Histone PF00125.19 EEQ75664.1 - 0.05 13.7 0.2 0.08 13.0 0.1 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Voltage_CLC PF00654.15 EEQ75665.1 - 1e-77 261.5 28.3 3e-75 253.4 19.6 2.3 1 1 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 EEQ75665.1 - 2.3e-13 49.6 0.0 2e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 CBS domain DUF2632 PF10943.3 EEQ75666.1 - 0.0014 18.2 0.5 0.0017 17.8 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2632) EamA PF00892.15 EEQ75666.1 - 0.032 14.2 12.4 0.11 12.5 8.5 1.8 1 1 0 1 1 1 0 EamA-like transporter family EmrE PF13536.1 EEQ75666.1 - 0.16 12.1 10.8 0.38 10.9 7.5 1.6 1 1 0 1 1 1 0 Multidrug resistance efflux transporter DUF4023 PF13215.1 EEQ75666.1 - 0.17 11.6 1.5 0.28 10.9 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) TPT PF03151.11 EEQ75666.1 - 0.4 10.3 5.7 0.31 10.6 2.4 1.7 1 1 1 2 2 2 0 Triose-phosphate Transporter family PPR_2 PF13041.1 EEQ75667.1 - 2.8e-49 164.8 10.1 5.8e-10 39.0 0.0 13.7 9 4 7 16 16 16 9 PPR repeat family PPR_3 PF13812.1 EEQ75667.1 - 5.8e-36 119.7 18.7 1.6e-06 27.9 0.0 14.9 15 0 0 15 15 15 8 Pentatricopeptide repeat domain PPR PF01535.15 EEQ75667.1 - 8.2e-30 100.6 14.9 0.00042 20.1 0.0 13.7 15 1 0 15 15 15 7 PPR repeat PPR_1 PF12854.2 EEQ75667.1 - 4.5e-23 80.4 3.4 1.7e-07 30.5 0.0 11.1 11 0 0 11 11 11 4 PPR repeat RPM2 PF08579.6 EEQ75667.1 - 5.8e-08 32.8 1.4 2.5e-05 24.3 0.0 4.7 6 0 0 6 6 6 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.1 EEQ75667.1 - 1.4e-05 25.2 4.2 38 5.3 0.0 8.5 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ75667.1 - 0.00057 20.1 2.4 2.4 8.5 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat BTAD PF03704.12 EEQ75667.1 - 0.0025 18.1 1.0 1.8 8.8 0.0 4.4 3 1 1 4 4 4 1 Bacterial transcriptional activator domain ECSIT PF06239.6 EEQ75667.1 - 0.006 15.4 0.1 8.8 5.1 0.0 3.5 3 0 0 3 3 3 1 Evolutionarily conserved signalling intermediate in Toll pathway PRANC PF09372.5 EEQ75667.1 - 0.17 11.8 0.1 27 4.8 0.1 3.1 2 0 0 2 2 2 0 PRANC domain APH PF01636.18 EEQ75668.1 - 1.1e-08 35.0 0.5 1.7e-08 34.5 0.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EEQ75668.1 - 0.015 14.4 0.1 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 EEQ75668.1 - 0.021 14.4 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Acyl_CoA_thio PF02551.10 EEQ75668.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA thioesterase GHMP_kinases_N PF00288.21 EEQ75669.1 - 2.9e-14 52.8 0.4 5.8e-13 48.6 0.2 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EEQ75669.1 - 1.3e-08 34.9 0.0 4.4e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal Rad60-SLD_2 PF13881.1 EEQ75671.1 - 4.5e-12 45.8 0.0 1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EEQ75671.1 - 0.0004 19.7 0.0 0.00069 18.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EEQ75671.1 - 0.0058 16.8 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain VirionAssem_T7 PF11653.3 EEQ75671.1 - 0.94 10.2 4.4 27 5.5 0.0 2.5 2 0 0 2 2 2 0 Bacteriophage T7 virion assembly protein PAT1 PF09770.4 EEQ75671.1 - 4.8 5.2 10.6 6 4.9 7.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UMP1 PF05348.6 EEQ75672.1 - 3.8e-20 72.1 0.0 4.7e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 DUF3591 PF12157.3 EEQ75672.1 - 0.046 12.1 0.0 0.055 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3591) Ribosom_S12_S23 PF00164.20 EEQ75673.1 - 5.8e-42 141.9 1.5 8.3e-42 141.4 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Glyco_transf_15 PF01793.11 EEQ75674.1 - 2.6e-142 473.6 7.6 3.2e-142 473.3 5.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PAT1 PF09770.4 EEQ75676.1 - 2.6e-262 872.7 8.3 2.9e-262 872.5 5.8 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Epimerase PF01370.16 EEQ75677.1 - 1.1e-47 162.4 0.0 1.5e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EEQ75677.1 - 4.1e-26 90.6 0.1 7e-26 89.9 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EEQ75677.1 - 3.9e-15 55.3 0.0 6e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EEQ75677.1 - 1.4e-12 47.1 0.0 2.1e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EEQ75677.1 - 3.4e-12 46.6 0.0 5.8e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EEQ75677.1 - 1.9e-11 43.4 0.0 2.6e-10 39.6 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EEQ75677.1 - 1.4e-10 41.5 0.0 2.2e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EEQ75677.1 - 4.4e-08 32.9 0.0 7.9e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EEQ75677.1 - 2e-06 26.9 0.0 7.6e-06 25.0 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein adh_short_C2 PF13561.1 EEQ75677.1 - 0.00078 19.2 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 EEQ75677.1 - 0.0011 18.2 0.0 0.0022 17.2 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 EEQ75677.1 - 0.0024 16.9 0.0 0.0035 16.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 EEQ75677.1 - 0.012 15.0 0.1 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 EEQ75677.1 - 0.017 14.0 0.2 0.03 13.2 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EEQ75677.1 - 0.057 13.0 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.20 EEQ75678.1 - 2e-12 47.3 0.0 1.8e-11 44.2 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EEQ75678.1 - 1.5e-08 34.5 0.0 3.8e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EEQ75678.1 - 0.00098 18.9 0.0 0.0023 17.7 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EEQ75678.1 - 0.098 12.0 0.0 0.34 10.3 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family G-patch PF01585.18 EEQ75679.1 - 1e-05 25.2 0.1 2.5e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EEQ75679.1 - 0.21 11.4 1.5 0.33 10.8 0.0 2.1 2 1 0 2 2 2 0 DExH-box splicing factor binding site Sec1 PF00995.18 EEQ75680.1 - 1.7e-136 456.1 0.0 2.1e-136 455.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SUV3_C PF12513.3 EEQ75681.1 - 2.3e-15 55.7 0.0 5.1e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EEQ75681.1 - 3.1e-09 36.5 0.1 9.7e-09 34.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TK PF00265.13 EEQ75681.1 - 0.082 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Thymidine kinase HA2 PF04408.18 EEQ75682.1 - 1.1e-29 102.4 0.2 2.9e-29 101.0 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EEQ75682.1 - 6.9e-26 90.3 0.1 1.6e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EEQ75682.1 - 5e-12 45.5 0.0 1.5e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 EEQ75682.1 - 3.3e-11 43.1 0.5 8.2e-11 41.8 0.3 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 EEQ75682.1 - 4.1e-05 23.1 0.1 0.0001 21.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EEQ75682.1 - 0.00018 20.5 0.0 0.00039 19.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EEQ75682.1 - 0.00038 20.5 0.0 0.001 19.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ75682.1 - 0.022 14.4 0.6 0.082 12.6 0.2 2.1 2 0 0 2 2 2 0 Part of AAA domain ResIII PF04851.10 EEQ75682.1 - 0.091 12.5 0.3 18 5.1 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit UPF0079 PF02367.12 EEQ75682.1 - 0.17 11.5 0.2 0.32 10.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF1509 PF07420.6 EEQ75682.1 - 1.1 8.4 10.8 2.2 7.4 7.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Npa1 PF11707.3 EEQ75684.1 - 1.2e-99 333.5 0.1 2.2e-99 332.5 0.1 1.5 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal M-inducer_phosp PF06617.8 EEQ75684.1 - 0.0097 14.9 0.3 0.19 10.7 0.0 2.3 2 0 0 2 2 2 1 M-phase inducer phosphatase DNA_ligase_A_N PF04675.9 EEQ75684.1 - 0.046 13.5 1.8 0.3 10.8 0.6 2.8 2 0 0 2 2 2 0 DNA ligase N terminus NUC153 PF08159.7 EEQ75685.1 - 2e-12 46.4 9.5 1.6e-11 43.5 0.1 3.9 3 0 0 3 3 3 3 NUC153 domain UPRTase PF14681.1 EEQ75686.1 - 2.1e-41 141.4 0.0 3.4e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.13 EEQ75687.1 - 9.3e-33 113.4 0.0 1.1e-32 113.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CPT PF07931.7 EEQ75687.1 - 1.5e-06 27.9 0.0 2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.1 EEQ75687.1 - 7.4e-06 26.7 0.0 8.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEQ75687.1 - 0.0027 16.8 0.0 0.006 15.6 0.0 1.6 1 1 1 2 2 2 1 Zeta toxin AAA_18 PF13238.1 EEQ75687.1 - 0.0044 17.3 0.0 0.0067 16.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.12 EEQ75687.1 - 0.037 13.8 0.1 0.053 13.3 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function DUF87 AAA_5 PF07728.9 EEQ75687.1 - 0.061 13.0 0.0 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CoaE PF01121.15 EEQ75687.1 - 0.081 12.3 0.1 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_29 PF13555.1 EEQ75687.1 - 0.089 12.3 0.1 0.26 10.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain MobB PF03205.9 EEQ75687.1 - 0.089 12.4 0.1 0.21 11.3 0.0 1.6 1 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EEQ75687.1 - 0.1 12.8 1.4 0.17 12.1 0.9 1.4 1 1 0 1 1 1 0 ABC transporter CLTH PF10607.4 EEQ75688.1 - 5.5e-36 123.4 0.1 7e-36 123.0 0.1 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EEQ75688.1 - 3.8e-09 35.9 0.0 6.9e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 LisH DUF1645 PF07816.6 EEQ75688.1 - 0.047 14.1 0.2 0.072 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Pyr_redox_2 PF07992.9 EEQ75689.1 - 2.5e-22 79.7 0.0 3.5e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEQ75689.1 - 1.5e-12 47.6 0.0 2.9e-10 40.3 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 EEQ75689.1 - 9.2e-07 27.7 0.1 2.6e-06 26.3 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EEQ75689.1 - 1.9e-06 26.9 0.7 7.6e-06 25.0 0.5 2.1 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EEQ75689.1 - 4e-06 26.2 0.4 1.2e-05 24.7 0.3 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 EEQ75689.1 - 1.3e-05 25.2 0.2 4.9e-05 23.3 0.0 2.1 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 EEQ75689.1 - 0.047 13.3 0.1 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain pair Nipped-B_C PF12830.2 EEQ75690.1 - 3.3e-54 183.3 7.0 4.3e-54 183.0 0.4 3.5 3 1 1 4 4 4 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EEQ75690.1 - 1.2e-12 47.4 2.4 3.6e-12 45.9 0.7 2.6 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 EEQ75690.1 - 5.4e-05 22.9 2.4 0.28 11.3 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat Adaptin_N PF01602.15 EEQ75690.1 - 0.013 13.8 10.2 0.0044 15.4 2.1 3.4 3 1 0 3 3 3 0 Adaptin N terminal region Cnd1 PF12717.2 EEQ75690.1 - 0.83 9.4 8.8 2.5 7.9 0.3 3.7 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 TFIIS_C PF01096.13 EEQ75691.1 - 6.1e-15 54.5 6.5 6.6e-15 54.4 0.4 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EEQ75691.1 - 3.5e-05 23.3 1.2 3.5e-05 23.3 0.8 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit zinc_ribbon_2 PF13240.1 EEQ75691.1 - 0.0032 16.8 11.4 1.3 8.6 0.0 4.0 4 0 0 4 4 4 1 zinc-ribbon domain Lar_restr_allev PF14354.1 EEQ75691.1 - 0.0041 17.3 7.7 0.19 12.0 0.9 3.1 1 1 2 3 3 3 1 Restriction alleviation protein Lar DZR PF12773.2 EEQ75691.1 - 0.0087 15.8 9.9 17 5.3 6.9 3.1 1 1 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 EEQ75691.1 - 0.012 14.9 13.4 0.51 9.7 1.3 3.6 2 2 1 3 3 3 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 EEQ75691.1 - 0.039 13.8 12.0 3.9 7.5 1.0 3.5 3 1 0 3 3 3 0 Zinc ribbon domain Zn_ribbon_recom PF13408.1 EEQ75691.1 - 0.049 13.8 6.8 0.35 11.1 0.4 2.7 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Terminase_GpA PF05876.7 EEQ75691.1 - 0.11 10.8 2.8 0.058 11.7 0.6 1.5 1 1 1 2 2 2 0 Phage terminase large subunit (GpA) C1_1 PF00130.17 EEQ75691.1 - 0.11 12.2 4.4 2.4 7.9 0.1 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-rbx1 PF12678.2 EEQ75691.1 - 0.13 12.3 2.0 0.14 12.3 0.6 1.6 1 1 1 2 2 2 0 RING-H2 zinc finger Rpr2 PF04032.11 EEQ75691.1 - 0.14 12.0 0.1 0.14 12.0 0.0 2.6 1 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain IBR PF01485.16 EEQ75691.1 - 0.17 11.7 5.7 1.3 8.9 0.1 2.6 2 1 0 2 2 2 0 IBR domain OrfB_Zn_ribbon PF07282.6 EEQ75691.1 - 0.27 10.8 7.5 0.64 9.7 0.2 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Prok-RING_1 PF14446.1 EEQ75691.1 - 0.31 10.7 7.8 4.7 7.0 0.7 3.5 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 Rubredoxin PF00301.15 EEQ75691.1 - 0.32 10.8 6.1 15 5.5 0.0 3.9 3 1 1 4 4 4 0 Rubredoxin Ribosomal_S27e PF01667.12 EEQ75691.1 - 0.72 9.4 0.0 0.72 9.4 0.0 3.2 3 1 1 4 4 4 0 Ribosomal protein S27 DUF164 PF02591.10 EEQ75691.1 - 0.76 9.6 4.1 85 3.0 0.0 3.9 4 0 0 4 4 4 0 Putative zinc ribbon domain Ogr_Delta PF04606.7 EEQ75691.1 - 0.78 9.4 9.5 4.1 7.1 2.4 3.2 3 1 0 3 3 3 0 Ogr/Delta-like zinc finger UPF0547 PF10571.4 EEQ75691.1 - 0.8 9.4 14.6 12 5.7 0.0 3.9 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 Baculo_LEF5_C PF11792.3 EEQ75691.1 - 0.8 9.1 6.4 0.22 10.9 0.2 2.7 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain DUF2387 PF09526.5 EEQ75691.1 - 0.96 9.4 4.9 2.3 8.1 0.1 2.6 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) GFA PF04828.9 EEQ75691.1 - 1.6 8.6 8.6 6.3 6.8 0.5 3.3 1 1 3 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme zf-CHY PF05495.7 EEQ75691.1 - 2.6 8.2 5.8 9.8 6.4 0.0 2.9 2 1 0 2 2 2 0 CHY zinc finger XPA_N PF01286.13 EEQ75691.1 - 3.2 7.5 10.9 12 5.7 0.1 4.0 4 0 0 4 4 4 0 XPA protein N-terminal Nudix_N_2 PF14803.1 EEQ75691.1 - 3.4 7.4 10.6 0.55 9.9 0.5 3.3 3 1 0 3 3 3 0 Nudix N-terminal Cys_rich_CPCC PF14206.1 EEQ75691.1 - 3.4 7.2 5.7 0.59 9.7 0.3 2.2 2 1 1 3 3 3 0 Cysteine-rich CPCC PHD PF00628.24 EEQ75691.1 - 4.2 7.1 14.4 39 4.0 1.7 3.7 2 2 2 4 4 4 0 PHD-finger zf-C4_Topoisom PF01396.14 EEQ75691.1 - 5.3 6.6 10.3 5.8 6.5 1.4 3.6 2 2 1 3 3 3 0 Topoisomerase DNA binding C4 zinc finger C1_2 PF03107.11 EEQ75691.1 - 6.3 7.0 7.7 1.2 9.3 0.2 2.6 3 0 0 3 3 2 0 C1 domain zf-IS66 PF13005.2 EEQ75691.1 - 6.4 6.8 9.2 44 4.1 0.2 3.6 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 zf-TFIIB PF13453.1 EEQ75691.1 - 7.9 5.7 7.8 3.6 6.8 0.9 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger A2L_zn_ribbon PF08792.5 EEQ75691.1 - 8.7 5.9 14.5 42 3.7 0.1 4.0 4 0 0 4 4 4 0 A2L zinc ribbon domain HEAT_2 PF13646.1 EEQ75692.1 - 6e-30 103.3 6.0 9.2e-15 54.7 0.0 3.8 2 2 3 5 5 5 2 HEAT repeats HEAT_PBS PF03130.11 EEQ75692.1 - 1.1e-18 65.7 0.5 0.0032 17.8 0.0 6.4 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EEQ75692.1 - 1.5e-07 31.6 7.7 0.029 14.8 0.0 5.0 2 2 3 5 5 5 3 HEAT-like repeat HEAT PF02985.17 EEQ75692.1 - 7.2e-06 25.6 5.5 6.4 7.1 0.0 6.2 7 0 0 7 7 7 2 HEAT repeat Arm PF00514.18 EEQ75692.1 - 0.014 15.2 0.4 21 5.0 0.0 3.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat ERAP1_C PF11838.3 EEQ75692.1 - 0.06 12.5 0.1 6 6.0 0.0 2.3 2 0 0 2 2 2 0 ERAP1-like C-terminal domain ETC_C1_NDUFA4 PF04800.7 EEQ75693.1 - 1.7e-36 124.1 1.6 2.4e-36 123.6 1.1 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region F1F0-ATPsyn_F PF10791.4 EEQ75694.1 - 6e-40 135.3 0.1 1.1e-39 134.5 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EEQ75694.1 - 0.031 14.3 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f MOZ_SAS PF01853.13 EEQ75696.1 - 6e-84 279.9 0.0 9.1e-84 279.3 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EEQ75696.1 - 9e-23 79.7 0.0 1.9e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EEQ75696.1 - 0.035 13.7 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Myb_Cef PF11831.3 EEQ75697.1 - 7e-67 225.0 0.3 7e-67 225.0 0.2 3.4 3 1 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EEQ75697.1 - 2.1e-19 69.2 3.7 1.1e-08 35.0 0.2 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEQ75697.1 - 1.1e-18 67.0 5.7 2.3e-12 46.8 1.1 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Nop53 PF07767.6 EEQ75698.1 - 2.3e-120 402.1 32.5 2.7e-120 401.9 22.5 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) HeLo PF14479.1 EEQ75698.1 - 1.5 8.4 11.6 3.5 7.3 8.1 1.6 1 0 0 1 1 1 0 Prion-inhibition and propagation RNase_T PF00929.19 EEQ75699.1 - 1.9e-26 93.3 0.0 2.9e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RNase_H2_suC PF08615.6 EEQ75700.1 - 5.5e-31 107.2 0.0 7.7e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) AF1Q PF15017.1 EEQ75700.1 - 7.9 6.4 10.9 2.2 8.2 3.8 2.3 1 1 1 2 2 2 0 Drug resistance and apoptosis regulator Alk_phosphatase PF00245.15 EEQ75702.1 - 1.2e-67 228.4 0.7 2.9e-67 227.2 0.5 1.6 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.17 EEQ75702.1 - 2.7e-05 23.6 0.2 4.4e-05 22.9 0.2 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EEQ75702.1 - 7.9e-05 21.9 0.7 0.00054 19.2 0.5 2.2 1 1 0 1 1 1 1 Sulfatase FTA4 PF13093.1 EEQ75702.1 - 0.0051 16.2 0.0 0.0074 15.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF229 PF02995.12 EEQ75702.1 - 0.025 12.9 0.3 0.038 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Metalloenzyme PF01676.13 EEQ75702.1 - 0.061 12.7 0.9 0.14 11.4 0.6 1.6 1 0 0 1 1 1 0 Metalloenzyme superfamily Pectinesterase PF01095.14 EEQ75702.1 - 0.061 11.8 0.1 0.099 11.1 0.1 1.3 1 0 0 1 1 1 0 Pectinesterase HHH_3 PF12836.2 EEQ75702.1 - 0.09 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif DcpS_C PF11969.3 EEQ75703.1 - 4.4e-30 104.2 0.0 7.1e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 EEQ75703.1 - 5.4e-29 100.7 0.0 8.6e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Peptidase_C12 PF01088.16 EEQ75704.1 - 8.9e-58 194.9 0.0 1e-57 194.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyoxalase_2 PF12681.2 EEQ75704.1 - 0.0069 16.9 0.0 0.016 15.8 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain APH PF01636.18 EEQ75706.1 - 6.1e-13 49.0 0.0 1.2e-12 48.1 0.0 1.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ75706.1 - 7.3e-05 22.4 0.3 0.0002 20.9 0.0 1.9 2 1 0 2 2 2 1 Choline/ethanolamine kinase LETM1 PF07766.8 EEQ75706.1 - 0.048 12.7 0.0 0.075 12.0 0.0 1.3 1 0 0 1 1 1 0 LETM1-like protein CheY-binding PF09078.6 EEQ75706.1 - 0.054 13.5 0.8 1.2 9.1 0.1 2.3 2 0 0 2 2 2 0 CheY binding GATase_4 PF13230.1 EEQ75710.1 - 2.1e-15 56.1 0.0 4.1e-13 48.6 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EEQ75710.1 - 5.5e-10 39.3 0.0 9.7e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EEQ75710.1 - 4.4e-06 25.6 0.1 0.00016 20.4 0.1 2.3 2 0 0 2 2 2 2 Glutamine amidotransferases class-II TctB PF07331.6 EEQ75711.1 - 0.27 10.9 5.9 0.22 11.2 3.0 1.6 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family RRM_1 PF00076.17 EEQ75712.1 - 4.7e-07 29.3 0.1 1e-06 28.2 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ75712.1 - 6.4e-07 29.2 0.0 1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pex14_N PF04695.8 EEQ75713.1 - 0.013 15.5 0.4 0.013 15.5 0.3 3.4 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Arrestin_C PF02752.17 EEQ75714.1 - 1.6e-23 83.3 0.0 1.3e-22 80.3 0.0 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EEQ75714.1 - 1.5e-07 31.3 0.1 0.0002 21.2 0.0 3.4 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain IFRD PF05004.8 EEQ75715.1 - 1.5e-34 119.5 0.1 2.1e-34 119.0 0.1 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Cnd3 PF12719.2 EEQ75715.1 - 0.013 14.5 0.0 0.029 13.3 0.0 1.5 1 1 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain Peptidase_C65 PF10275.4 EEQ75715.1 - 0.046 13.0 0.4 1.6 8.0 0.1 2.2 2 0 0 2 2 2 0 Peptidase C65 Otubain Corona_nucleoca PF00937.13 EEQ75715.1 - 0.05 12.5 9.2 0.081 11.8 6.4 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF2413 PF10310.4 EEQ75715.1 - 0.055 12.2 6.4 0.011 14.6 1.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) Pkinase PF00069.20 EEQ75716.1 - 2e-60 204.1 0.0 2.6e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ75716.1 - 2.1e-34 118.7 0.0 3e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ75716.1 - 3.3e-05 23.0 0.0 5.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEQ75716.1 - 0.11 12.2 0.0 0.33 10.6 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family SH2_2 PF14633.1 EEQ75717.1 - 4e-81 271.2 0.0 4e-81 271.2 0.0 2.0 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 EEQ75717.1 - 3.8e-38 130.1 4.6 3.8e-38 130.1 3.2 3.5 3 0 0 3 3 3 1 Death-like domain of SPT6 HHH_7 PF14635.1 EEQ75717.1 - 8.1e-31 106.2 0.0 1.6e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 EEQ75717.1 - 3.9e-29 101.1 0.0 1e-28 99.7 0.0 1.8 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 EEQ75717.1 - 8.4e-23 80.3 28.0 8.4e-23 80.3 19.4 5.4 5 1 1 6 6 6 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 EEQ75717.1 - 3.1e-20 72.3 4.7 9.2e-19 67.6 3.2 2.8 1 1 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 EEQ75717.1 - 0.00081 19.1 0.0 0.0022 17.7 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 EEQ75717.1 - 0.026 14.4 0.0 0.091 12.7 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF1570 PF07607.6 EEQ75717.1 - 0.078 12.9 1.0 0.3 11.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1570) MFS_1 PF07690.11 EEQ75718.1 - 7.5e-35 120.2 41.8 1.4e-33 116.1 29.2 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ75718.1 - 1.9e-14 52.7 19.6 1.7e-13 49.6 13.6 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEQ75718.1 - 1.6e-13 50.1 11.8 1.6e-13 50.1 8.2 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter Oxysterol_BP PF01237.13 EEQ75720.1 - 8.3e-119 396.1 0.1 1.9e-118 395.0 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 EEQ75720.1 - 5.2e-40 135.4 0.2 1e-39 134.4 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EEQ75720.1 - 0.0019 18.4 3.0 0.0032 17.6 0.2 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain GOLD_2 PF13897.1 EEQ75720.1 - 0.011 15.9 0.5 0.046 13.9 0.2 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking PH_3 PF14593.1 EEQ75720.1 - 0.051 13.4 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 PH domain ECR1_N PF14382.1 EEQ75721.1 - 2e-09 36.5 0.0 5.7e-09 35.1 0.0 1.8 1 1 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EEQ75721.1 - 0.0089 15.9 0.1 0.11 12.4 0.0 2.3 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 Btz PF09405.5 EEQ75722.1 - 8.2e-29 100.2 2.5 8.2e-29 100.2 1.8 1.8 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding RRM_1 PF00076.17 EEQ75723.1 - 1.8e-27 94.7 0.8 7.8e-16 57.4 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ75723.1 - 2.9e-24 84.8 0.1 1.3e-12 47.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ75723.1 - 6.5e-09 35.5 0.3 0.00066 19.4 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEQ75723.1 - 0.00056 19.6 0.1 0.24 11.2 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif CDC45 PF02724.9 EEQ75723.1 - 0.068 11.1 4.1 0.096 10.7 2.9 1.2 1 0 0 1 1 1 0 CDC45-like protein HSP90 PF00183.13 EEQ75723.1 - 0.11 10.8 3.7 0.18 10.1 2.5 1.2 1 0 0 1 1 1 0 Hsp90 protein TLP-20 PF06088.6 EEQ75723.1 - 0.12 12.0 1.5 0.36 10.4 1.0 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) eIF-3c_N PF05470.7 EEQ75723.1 - 0.47 8.4 5.5 0.69 7.9 3.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Ino80_Iec3 PF14612.1 EEQ75724.1 - 6.8e-89 297.8 2.0 8.4e-89 297.5 1.4 1.1 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling IF2_N PF04760.10 EEQ75724.1 - 0.12 12.0 0.3 0.2 11.3 0.2 1.3 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region GvpG PF05120.7 EEQ75724.1 - 3 7.6 6.0 0.27 11.0 0.6 1.8 2 0 0 2 2 2 0 Gas vesicle protein G Pkinase PF00069.20 EEQ75725.1 - 6.8e-16 58.2 0.0 1.1e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ75725.1 - 3e-06 26.4 0.0 8.1e-06 25.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Orthopox_F8 PF05886.6 EEQ75725.1 - 0.11 12.3 5.1 0.34 10.7 3.5 1.8 1 0 0 1 1 1 0 Orthopoxvirus F8 protein ZZ PF00569.12 EEQ75726.1 - 9.7e-08 31.4 32.7 0.00049 19.5 5.2 3.3 3 0 0 3 3 3 2 Zinc finger, ZZ type C1_3 PF07649.7 EEQ75726.1 - 7.8 6.6 27.7 0.8 9.7 7.9 2.8 2 0 0 2 2 2 0 C1-like domain LETM1 PF07766.8 EEQ75728.1 - 1.9e-07 30.4 1.5 0.0014 17.6 0.1 2.1 2 0 0 2 2 2 2 LETM1-like protein DUF3439 PF11921.3 EEQ75728.1 - 0.0012 18.5 1.3 0.0012 18.5 0.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) Mto2_bdg PF12808.2 EEQ75729.1 - 0.27 11.3 4.1 0.12 12.5 0.6 2.1 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Glyco_transf_20 PF00982.16 EEQ75730.1 - 9.8e-148 492.5 0.0 1.4e-147 492.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EEQ75730.1 - 1.6e-88 295.6 0.0 2.4e-88 294.9 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 EEQ75730.1 - 7.9e-05 22.3 0.0 0.19 11.2 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEQ75730.1 - 0.02 15.0 0.2 0.12 12.4 0.1 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Acetyltransf_1 PF00583.19 EEQ75731.1 - 6.2e-15 54.9 0.1 1.8e-14 53.5 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EEQ75731.1 - 1.7e-07 31.3 0.0 2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEQ75731.1 - 2.1e-06 27.8 0.0 3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEQ75731.1 - 0.00011 21.9 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EEQ75731.1 - 0.00019 21.1 0.0 0.00027 20.6 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EEQ75731.1 - 0.0044 16.8 0.0 0.0058 16.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pyr_redox_3 PF13738.1 EEQ75732.1 - 6.5e-19 68.7 0.0 2.3e-18 67.0 0.0 1.9 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEQ75732.1 - 1.9e-08 33.6 0.0 2.8e-05 23.2 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EEQ75732.1 - 3.2e-07 28.9 0.1 1.5e-06 26.7 0.1 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EEQ75732.1 - 2.3e-06 27.5 0.0 6.5e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EEQ75732.1 - 0.038 13.7 0.0 0.34 10.6 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding MFS_1 PF07690.11 EEQ75733.1 - 3.7e-17 62.0 53.4 3.9e-17 62.0 29.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PP28 PF10252.4 EEQ75734.1 - 5.3e-32 109.6 19.1 5.3e-32 109.6 13.2 3.2 2 1 1 3 3 3 2 Casein kinase substrate phosphoprotein PP28 CAF-1_p150 PF11600.3 EEQ75734.1 - 0.023 14.0 32.8 0.0099 15.2 14.2 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal UNC-50 PF05216.8 EEQ75735.1 - 2.6e-85 285.3 1.8 3.8e-85 284.7 1.2 1.2 1 0 0 1 1 1 1 UNC-50 family HCV_capsid PF01543.12 EEQ75736.1 - 1.1 9.2 5.4 0.12 12.3 0.6 1.7 2 0 0 2 2 2 0 Hepatitis C virus capsid protein Sec7 PF01369.15 EEQ75737.1 - 5.3e-44 150.1 0.0 1.2e-43 148.9 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EEQ75737.1 - 5.8e-17 61.9 0.2 1.9e-16 60.3 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Lzipper-MIP1 PF14389.1 EEQ75737.1 - 0.048 13.7 0.2 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Mto2_bdg PF12808.2 EEQ75738.1 - 1.3e-28 98.8 30.0 1.4e-18 66.7 12.9 9.7 10 0 0 10 10 10 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Microtub_assoc PF07989.6 EEQ75738.1 - 1.3e-19 69.8 7.4 1.3e-19 69.8 5.1 6.6 7 1 1 8 8 8 1 Microtubule associated Reo_sigmaC PF04582.7 EEQ75738.1 - 4e-05 22.9 3.0 4e-05 22.9 2.1 5.1 5 1 1 6 6 6 2 Reovirus sigma C capsid protein Fib_alpha PF08702.5 EEQ75738.1 - 0.0077 16.3 9.6 0.0077 16.3 6.7 7.5 4 2 3 7 7 7 3 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 EEQ75738.1 - 0.099 12.4 0.1 0.099 12.4 0.0 7.2 3 1 3 7 7 7 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 EEQ75738.1 - 5.2 6.8 30.9 0.56 10.0 0.6 5.2 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Zn_clus PF00172.13 EEQ75739.1 - 1.9e-09 37.2 12.2 3e-09 36.6 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.8 EEQ75739.1 - 0.87 9.4 21.1 1.1 9.0 14.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EEQ75739.1 - 4.5 5.3 41.0 5.7 5.0 28.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Aldose_epim PF01263.15 EEQ75740.1 - 4e-54 183.7 0.0 5.7e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase zf-CCHC_4 PF14392.1 EEQ75743.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Zinc knuckle QRPTase_C PF01729.14 EEQ75744.1 - 1.3e-47 161.4 0.2 4e-47 159.8 0.2 1.7 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EEQ75744.1 - 4.5e-25 87.2 0.0 1.1e-24 86.0 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain LysR_substrate PF03466.15 EEQ75744.1 - 0.12 11.4 0.2 0.66 9.0 0.1 1.8 1 1 1 2 2 2 0 LysR substrate binding domain Ras PF00071.17 EEQ75745.1 - 4.8e-26 91.0 0.0 3.3e-24 85.1 0.0 2.1 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EEQ75745.1 - 0.0028 18.1 0.0 0.0066 16.9 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein PAS_9 PF13426.1 EEQ75746.1 - 1.4e-21 76.8 0.0 2.8e-13 50.1 0.0 3.7 3 0 0 3 3 3 3 PAS domain GATA PF00320.22 EEQ75746.1 - 1.9e-14 52.6 9.0 6.9e-14 50.9 6.3 2.1 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 EEQ75746.1 - 6.9e-14 51.7 0.0 2.7e-09 36.9 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS PF00989.19 EEQ75746.1 - 3.4e-07 30.0 0.0 0.08 12.7 0.0 3.7 3 1 0 3 3 3 2 PAS fold PAS_11 PF14598.1 EEQ75746.1 - 5.9e-05 22.9 0.0 0.0094 15.8 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 EEQ75746.1 - 0.0019 18.2 0.0 4.5 7.3 0.0 3.4 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.1 EEQ75746.1 - 0.067 13.0 0.0 0.26 11.2 0.0 2.0 1 0 0 1 1 1 0 PAS domain Peptidase_S41 PF03572.13 EEQ75748.1 - 2e-10 40.3 0.0 4.1e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 PLDc PF00614.17 EEQ75749.1 - 5.8e-14 51.3 0.3 1.4e-06 27.8 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EEQ75749.1 - 2.1e-12 46.9 0.0 1e-07 31.7 0.0 2.8 2 1 0 2 2 2 2 PLD-like domain PX PF00787.19 EEQ75749.1 - 6.5e-09 35.5 0.4 2.2e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 PX domain Abhydrolase_6 PF12697.2 EEQ75750.1 - 1.4e-08 34.9 0.0 1.8e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ75750.1 - 8.6e-07 28.8 0.0 2.4e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEQ75750.1 - 0.032 13.4 0.0 1.7 7.7 0.0 2.2 1 1 0 2 2 2 0 Prolyl oligopeptidase family Ribosomal_L18e PF00828.14 EEQ75751.1 - 7.7e-35 120.0 0.0 9.5e-35 119.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Helicase_C_2 PF13307.1 EEQ75752.1 - 1.6e-56 190.8 0.0 3.7e-56 189.6 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EEQ75752.1 - 5.6e-46 156.1 0.6 1.9e-45 154.3 0.4 1.8 1 1 0 1 1 1 1 DEAD_2 SNF2_N PF00176.18 EEQ75752.1 - 0.063 12.0 0.0 0.13 11.0 0.0 1.5 1 0 0 1 1 1 0 SNF2 family N-terminal domain Sel1 PF08238.7 EEQ75753.1 - 1.8e-14 53.8 24.0 1.7e-06 28.4 0.1 6.9 7 0 0 7 7 7 4 Sel1 repeat TPR_11 PF13414.1 EEQ75753.1 - 0.001 18.6 0.1 0.001 18.6 0.1 2.6 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EEQ75753.1 - 0.0013 18.2 0.2 0.0058 16.2 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ75753.1 - 0.016 15.1 0.3 0.15 12.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ75753.1 - 0.071 13.7 1.2 0.6 10.8 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TBPIP PF07106.8 EEQ75754.1 - 6.9e-15 55.0 0.1 8.5e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Macoilin PF09726.4 EEQ75754.1 - 0.001 17.5 1.1 0.0012 17.2 0.8 1.0 1 0 0 1 1 1 1 Transmembrane protein Mito_fiss_reg PF05308.6 EEQ75754.1 - 0.0042 16.5 0.3 0.0057 16.0 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial fission regulator DUF4349 PF14257.1 EEQ75754.1 - 0.0049 16.1 1.1 0.0061 15.8 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) DUF4140 PF13600.1 EEQ75754.1 - 0.0055 17.1 1.4 0.011 16.1 1.0 1.6 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) DUF2267 PF10025.4 EEQ75754.1 - 0.019 15.0 1.7 0.046 13.7 1.2 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) DivIC PF04977.10 EEQ75754.1 - 0.25 10.8 0.1 0.25 10.8 0.1 1.8 2 0 0 2 2 2 0 Septum formation initiator Bromodomain PF00439.20 EEQ75757.1 - 7.8e-30 102.6 5.1 4.2e-17 61.8 1.0 2.7 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 EEQ75757.1 - 1e-16 60.7 0.6 2e-16 59.8 0.4 1.5 1 0 0 1 1 1 1 BAH domain Nucleoplasmin PF03066.10 EEQ75757.1 - 0.14 11.6 6.6 0.32 10.5 4.6 1.6 1 0 0 1 1 1 0 Nucleoplasmin OTU PF02338.14 EEQ75758.1 - 6.2e-12 46.1 0.0 1.2e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Oxysterol_BP PF01237.13 EEQ75759.1 - 7.1e-57 192.4 0.0 2.8e-56 190.5 0.0 1.7 1 1 0 1 1 1 1 Oxysterol-binding protein Cnd1_N PF12922.2 EEQ75760.1 - 5.9e-58 195.2 0.1 1.6e-57 193.8 0.1 1.8 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 EEQ75760.1 - 4.1e-54 183.1 2.9 3.7e-51 173.4 0.7 3.1 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EEQ75760.1 - 9e-12 45.1 6.0 8.5e-06 25.9 0.0 5.4 4 2 1 5 5 5 2 HEAT repeats HEAT PF02985.17 EEQ75760.1 - 9.9e-10 37.6 5.4 0.062 13.4 0.0 6.3 6 0 0 6 6 6 2 HEAT repeat Adaptin_N PF01602.15 EEQ75760.1 - 3.1e-07 29.1 6.3 0.008 14.5 0.1 4.5 4 1 1 5 5 5 3 Adaptin N terminal region HEAT_EZ PF13513.1 EEQ75760.1 - 0.00012 22.4 9.1 0.24 11.9 0.0 5.9 5 1 1 6 6 6 2 HEAT-like repeat DUF2435 PF10363.4 EEQ75760.1 - 0.00085 19.1 0.1 5.5 6.9 0.0 4.2 3 1 1 4 4 4 2 Protein of unknown function (DUF2435) Cohesin_HEAT PF12765.2 EEQ75760.1 - 0.024 14.6 8.0 7.2 6.6 0.1 5.5 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion plasmid_Toxin PF12703.2 EEQ75760.1 - 0.057 13.2 0.7 3.8 7.3 0.1 2.8 2 0 0 2 2 2 0 Toxin of toxin-antitoxin type 1 system Cnd3 PF12719.2 EEQ75760.1 - 0.11 11.4 7.2 0.13 11.2 1.0 3.6 2 2 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Pkinase PF00069.20 EEQ75761.1 - 2.8e-35 121.7 0.0 7.3e-34 117.0 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ75761.1 - 8.1e-06 25.0 0.0 0.057 12.4 0.0 2.5 2 1 1 3 3 3 2 Protein tyrosine kinase PCMT PF01135.14 EEQ75762.1 - 2.2e-58 197.2 0.0 4e-58 196.4 0.0 1.3 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EEQ75762.1 - 1.2e-06 28.2 0.0 1.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ75762.1 - 4.9e-06 27.1 0.0 8.5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EEQ75762.1 - 1.5e-05 24.6 0.0 2.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ75762.1 - 4.5e-05 23.2 0.0 6.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ75762.1 - 0.0004 20.6 0.0 0.00085 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ75762.1 - 0.0038 17.2 0.0 0.0067 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EEQ75762.1 - 0.0086 15.4 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_11 PF08241.7 EEQ75762.1 - 0.042 14.3 0.0 0.077 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EEQ75762.1 - 0.047 13.0 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.15 EEQ75762.1 - 0.11 11.4 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DnaJ PF00226.26 EEQ75763.1 - 7.5e-24 83.2 1.1 7.5e-24 83.2 0.8 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 EEQ75763.1 - 1.5e-18 66.1 1.4 1.2e-07 31.2 0.0 5.3 4 2 2 6 6 6 4 TPR repeat TPR_1 PF00515.23 EEQ75763.1 - 1.5e-14 52.8 2.3 0.00048 19.6 0.0 6.4 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ75763.1 - 3.2e-14 51.6 5.7 0.036 13.9 0.0 7.5 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ75763.1 - 1e-10 41.3 2.0 0.017 14.9 0.1 4.5 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ75763.1 - 6e-10 38.8 2.6 2 9.2 0.0 7.2 3 3 5 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ75763.1 - 6.6e-10 38.0 0.6 0.038 13.7 0.0 7.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ75763.1 - 8.8e-10 38.7 7.9 0.00042 20.6 0.3 5.3 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ75763.1 - 2.9e-07 30.9 7.9 0.82 10.4 2.3 5.3 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ75763.1 - 9.4e-06 25.7 4.5 11 6.7 0.0 8.0 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ75763.1 - 1.7e-05 24.6 1.8 0.11 12.7 0.0 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ75763.1 - 1.9e-05 24.5 6.7 0.99 9.3 0.0 6.1 3 2 1 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EEQ75763.1 - 0.0011 19.0 8.8 13 6.0 2.8 4.8 4 2 3 7 7 6 0 Anaphase-promoting complex, cyclosome, subunit 3 RPT PF13446.1 EEQ75763.1 - 0.043 13.2 0.0 0.21 11.0 0.0 2.2 1 1 0 1 1 1 0 A repeated domain in UCH-protein DNA_pack_N PF02500.10 EEQ75763.1 - 0.07 12.6 1.4 0.11 12.0 0.9 1.3 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus Syntaxin_2 PF14523.1 EEQ75763.1 - 0.85 9.6 5.2 1.7 8.7 1.4 2.6 2 0 0 2 2 2 0 Syntaxin-like protein RF-1 PF00472.15 EEQ75764.1 - 3.1e-33 113.9 0.6 7.1e-33 112.8 0.4 1.6 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EEQ75764.1 - 1.1e-25 89.5 0.0 2.9e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 PCRF domain Mito_carr PF00153.22 EEQ75765.1 - 5.9e-30 102.8 1.3 5.1e-17 61.3 0.1 4.8 4 1 1 5 5 5 4 Mitochondrial carrier protein VIT1 PF01988.14 EEQ75765.1 - 0.25 10.8 3.0 1.2 8.5 0.0 2.7 2 1 1 3 3 3 0 VIT family DEAD PF00270.24 EEQ75766.1 - 4e-42 143.5 0.1 5.8e-42 143.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ75766.1 - 9.8e-24 83.0 0.1 1.9e-23 82.1 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EEQ75766.1 - 0.039 13.0 0.0 0.093 11.7 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF2457 PF10446.4 EEQ75767.1 - 7.4e-178 591.9 38.0 7.4e-178 591.9 26.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) Arf PF00025.16 EEQ75768.1 - 6.3e-62 207.8 0.0 7.1e-62 207.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EEQ75768.1 - 3e-08 32.7 0.2 0.00011 21.0 0.0 2.3 1 1 0 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 EEQ75768.1 - 1.5e-07 31.3 0.0 3.3e-07 30.2 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 EEQ75768.1 - 2.4e-07 30.1 0.0 3.2e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EEQ75768.1 - 2.5e-06 27.9 0.0 3.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EEQ75768.1 - 4.6e-05 22.6 0.0 5.4e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EEQ75768.1 - 6.3e-05 22.4 0.0 8.6e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 EEQ75768.1 - 0.0055 16.1 0.0 0.33 10.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EEQ75768.1 - 0.08 12.4 0.0 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EEQ75768.1 - 0.14 11.9 0.0 3.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Metallophos PF00149.23 EEQ75769.1 - 1.4e-44 151.9 0.2 1.7e-44 151.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LRR_4 PF12799.2 EEQ75770.1 - 1.9e-19 68.8 8.5 4.5e-08 32.5 0.9 5.9 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEQ75770.1 - 5.4e-14 51.6 18.1 7.8e-08 31.9 2.8 4.2 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 EEQ75770.1 - 2.4e-11 42.0 10.0 0.64 10.2 0.1 7.0 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_6 PF13516.1 EEQ75770.1 - 3.2e-06 26.6 3.8 6.2 7.2 0.2 6.3 7 0 0 7 7 7 2 Leucine Rich repeat LRR_7 PF13504.1 EEQ75770.1 - 3.3e-05 23.3 9.2 7.9 7.1 0.2 7.0 7 0 0 7 7 7 1 Leucine rich repeat DUF3336 PF11815.3 EEQ75771.1 - 1.1e-49 167.6 1.4 1.7e-49 167.0 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EEQ75771.1 - 2.5e-19 70.0 0.0 2.1e-18 67.0 0.0 2.4 2 1 0 2 2 2 1 Patatin-like phospholipase TPR_11 PF13414.1 EEQ75772.1 - 3.4e-23 81.0 20.2 5.5e-06 25.9 1.4 8.4 7 1 2 9 9 9 4 TPR repeat TPR_19 PF14559.1 EEQ75772.1 - 5.2e-20 71.5 16.0 2.8e-06 27.5 0.0 7.6 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ75772.1 - 5.3e-16 57.4 11.7 0.049 13.8 0.0 8.6 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ75772.1 - 1.3e-14 54.4 17.3 1.4e-05 25.6 0.5 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ75772.1 - 5.1e-13 48.4 17.3 0.0003 21.1 0.4 8.4 7 3 3 10 10 8 4 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ75772.1 - 2.1e-09 37.1 24.9 0.0048 16.8 1.2 7.3 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ75772.1 - 1.9e-08 33.5 29.7 0.17 11.8 0.4 9.5 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ75772.1 - 2.6e-08 33.0 23.2 0.029 14.1 0.5 8.6 9 1 0 9 9 8 3 Tetratricopeptide repeat Apc3 PF12895.2 EEQ75772.1 - 3.1e-08 33.6 18.4 0.008 16.2 0.4 5.5 6 0 0 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EEQ75772.1 - 0.00039 19.9 12.9 2 8.3 0.0 5.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 EEQ75772.1 - 0.002 17.2 7.5 1.7 7.6 0.0 3.8 3 1 0 4 4 4 2 Tetratricopeptide repeat ChAPs PF09295.5 EEQ75772.1 - 0.004 15.9 1.2 0.46 9.2 0.0 2.6 3 0 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.1 EEQ75772.1 - 0.0061 16.6 4.6 8 6.6 0.0 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ75772.1 - 0.0091 15.8 0.2 0.0091 15.8 0.1 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EEQ75772.1 - 0.028 14.6 5.4 1.3 9.2 0.1 3.6 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation NARP1 PF12569.3 EEQ75772.1 - 0.049 12.3 4.3 5.5 5.6 0.4 3.2 2 1 0 3 3 3 0 NMDA receptor-regulated protein 1 TPR_1 PF00515.23 EEQ75772.1 - 0.17 11.5 35.3 0.49 10.0 0.7 9.9 10 1 1 11 11 11 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ75772.1 - 2.6 8.7 16.1 6.3 7.4 0.0 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 EEQ75772.1 - 4.5 7.9 7.8 38 5.1 0.3 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat SAM_2 PF07647.12 EEQ75774.1 - 1.5e-08 34.3 0.1 2.7e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EEQ75774.1 - 9.5e-05 22.5 0.2 0.0002 21.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Rab5ip PF07019.7 EEQ75775.1 - 5e-09 36.1 9.8 9.1e-08 32.1 6.8 2.1 1 1 0 1 1 1 1 Rab5-interacting protein (Rab5ip) MFS_1 PF07690.11 EEQ75776.1 - 6e-28 97.5 14.8 6e-28 97.5 10.2 3.6 1 1 2 3 3 3 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ75776.1 - 2e-15 56.0 10.5 3.3e-15 55.3 7.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Methuselah_N PF06652.7 EEQ75777.1 - 0.027 14.0 0.3 0.036 13.6 0.2 1.1 1 0 0 1 1 1 0 Methuselah N-terminus 7TM_GPCR_Srsx PF10320.4 EEQ75777.1 - 0.047 12.8 1.0 0.061 12.4 0.7 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Sulfate_transp PF00916.15 EEQ75778.1 - 1.2e-66 224.5 9.6 8.4e-47 159.4 0.5 2.8 2 1 1 3 3 3 2 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EEQ75778.1 - 1.3e-32 111.2 1.8 1.3e-32 111.2 1.3 3.0 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EEQ75778.1 - 5.7e-08 32.1 0.0 1.3e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 STAS domain SNN_transmemb PF09049.5 EEQ75778.1 - 6.8 6.4 9.6 0.092 12.4 0.8 2.3 2 0 0 2 2 2 0 Stannin transmembrane DnaJ PF00226.26 EEQ75779.1 - 1.7e-25 88.5 3.3 2.7e-25 87.8 2.3 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EEQ75779.1 - 5.8e-24 83.7 0.5 5.5e-21 74.2 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EEQ75779.1 - 1.3e-10 41.1 16.4 2.3e-10 40.3 11.4 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EEQ75779.1 - 0.024 14.3 2.3 0.024 14.3 1.6 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family dCMP_cyt_deam_1 PF00383.17 EEQ75782.1 - 3.3e-21 74.8 0.1 4.8e-21 74.3 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EEQ75782.1 - 0.0094 15.8 2.1 1 9.1 1.5 2.2 1 1 1 2 2 2 2 Bd3614-like deaminase XOO_2897-deam PF14440.1 EEQ75782.1 - 0.051 13.2 0.0 0.1 12.2 0.0 1.5 1 1 1 2 2 2 0 Xanthomonas XOO_2897-like deaminase APOBEC_N PF08210.6 EEQ75782.1 - 0.056 13.0 0.1 0.076 12.6 0.1 1.4 1 1 0 1 1 1 0 APOBEC-like N-terminal domain URO-D PF01208.12 EEQ75783.1 - 5.7e-123 410.1 0.0 6.5e-123 410.0 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) WD40 PF00400.27 EEQ75784.1 - 3e-05 23.7 2.7 0.19 11.6 0.2 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat Ribosomal_L10 PF00466.15 EEQ75785.1 - 1.2e-25 89.2 0.3 3.3e-25 87.9 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EEQ75785.1 - 6.5e-15 55.3 7.7 1.8e-14 53.8 4.3 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF809 PF05663.6 EEQ75785.1 - 0.075 12.9 0.2 0.16 11.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Vps53_N PF04100.7 EEQ75786.1 - 1.4e-105 353.2 4.7 3e-105 352.1 3.2 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 EEQ75786.1 - 2.1e-06 26.8 9.6 2.1e-06 26.8 6.7 1.8 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 EEQ75786.1 - 0.0014 18.4 5.1 0.0063 16.3 3.5 2.1 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF1826 PF08856.6 EEQ75786.1 - 2.7 7.7 8.3 0.55 9.9 1.8 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1826) TAP_C PF03943.8 EEQ75787.1 - 1.3e-11 43.6 0.0 2.4e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 EEQ75787.1 - 2.2e-11 43.0 4.0 1.5e-08 34.0 0.1 2.6 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) NTF2 PF02136.15 EEQ75787.1 - 2.6e-06 27.7 0.0 8.1e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_1 PF00560.28 EEQ75787.1 - 1.8e-05 24.1 0.1 0.065 13.2 0.0 3.3 2 0 0 2 2 2 2 Leucine Rich Repeat LRR_8 PF13855.1 EEQ75787.1 - 0.00042 19.9 0.4 0.00095 18.8 0.3 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_6 PF13516.1 EEQ75787.1 - 0.0022 17.8 0.0 0.36 11.0 0.0 3.0 2 0 0 2 2 2 1 Leucine Rich repeat LRR_7 PF13504.1 EEQ75787.1 - 0.012 15.6 0.3 1 9.8 0.0 3.2 3 0 0 3 3 3 0 Leucine rich repeat LRR_9 PF14580.1 EEQ75787.1 - 0.025 14.1 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat COPIIcoated_ERV PF07970.7 EEQ75788.1 - 3.6e-70 236.0 0.1 2.8e-46 157.9 0.0 2.6 2 1 1 3 3 3 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EEQ75788.1 - 1.3e-34 117.9 0.0 2.4e-33 113.9 0.0 2.2 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Bact_transglu_N PF08379.5 EEQ75788.1 - 0.081 13.2 0.0 0.44 10.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial transglutaminase-like N-terminal region PH PF00169.24 EEQ75789.1 - 2.5e-05 24.4 0.3 0.00024 21.2 0.0 2.6 2 1 0 2 2 2 1 PH domain PH_9 PF15410.1 EEQ75789.1 - 0.011 15.9 0.0 0.033 14.3 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain zf-C2H2_4 PF13894.1 EEQ75792.1 - 6.3e-26 88.7 53.2 0.0023 18.1 0.0 10.6 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ75792.1 - 3.6e-24 83.6 55.1 0.00079 19.6 0.7 10.5 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEQ75792.1 - 8.7e-17 60.5 53.8 0.00015 21.9 0.6 10.7 11 0 0 11 11 11 7 Zinc-finger double domain GAGA PF09237.6 EEQ75792.1 - 1.8e-05 24.2 0.1 1.8e-05 24.2 0.1 2.6 3 0 0 3 3 3 1 GAGA factor zf-C2H2_jaz PF12171.3 EEQ75792.1 - 6.7e-05 22.9 11.6 5.3 7.3 0.1 8.4 9 0 0 9 9 9 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EEQ75792.1 - 0.0068 16.2 6.7 42 4.2 0.1 6.5 6 0 0 6 6 6 0 C2H2-type zinc finger zf-met PF12874.2 EEQ75792.1 - 0.1 12.8 10.3 1.3e+02 2.9 0.0 7.6 8 0 0 8 8 8 0 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 EEQ75792.1 - 0.14 11.8 21.8 0.46 10.1 0.1 5.3 4 1 1 5 5 5 0 Ogr/Delta-like zinc finger RNA_pol_Rpb6 PF01192.17 EEQ75793.1 - 2.9e-24 84.5 0.2 4.4e-24 83.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 MFS_1 PF07690.11 EEQ75794.1 - 1.8e-21 76.2 54.5 5.1e-17 61.6 22.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.19 EEQ75795.1 - 1.6e-12 47.2 0.1 2.4e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EEQ75795.1 - 1.3e-05 24.8 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EEQ75795.1 - 0.0003 20.9 0.0 0.00041 20.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEQ75795.1 - 0.0008 19.5 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EEQ75795.1 - 0.0023 17.8 0.1 0.003 17.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEQ75795.1 - 0.032 14.1 0.1 0.046 13.5 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain HET PF06985.6 EEQ75797.1 - 3.9e-24 85.3 0.0 7e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PCI PF01399.22 EEQ75798.1 - 2.9e-11 43.5 0.5 1.5e-09 38.0 0.0 3.2 2 0 0 2 2 2 1 PCI domain Cupin_3 PF05899.7 EEQ75799.1 - 0.099 12.0 0.0 0.18 11.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) G-gamma PF00631.17 EEQ75800.1 - 1.5e-24 85.4 0.1 1.8e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 GGL domain DUF3382 PF11862.3 EEQ75801.1 - 0.073 12.9 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) Rdx PF10262.4 EEQ75802.1 - 8e-25 86.6 0.0 1.7e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 Rdx family PDEase_I PF00233.14 EEQ75803.1 - 1.2e-50 172.4 0.0 2e-49 168.4 0.0 2.2 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DEAD PF00270.24 EEQ75805.1 - 1.4e-18 67.0 0.1 3.3e-18 65.7 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ75805.1 - 4.3e-09 36.1 0.0 1.1e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ75805.1 - 7.6e-06 25.8 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.1 EEQ75805.1 - 1.9e-05 24.7 1.0 4.8e-05 23.4 0.1 2.2 2 1 0 2 2 2 1 Helix-hairpin-helix domain DUF336 PF03928.9 EEQ75805.1 - 0.024 14.4 0.1 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF336) Adeno_IVa2 PF02456.10 EEQ75805.1 - 0.073 11.7 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein zf-HC5HC2H_2 PF13832.1 EEQ75806.1 - 9.6e-24 83.5 1.1 9.6e-24 83.5 0.7 4.1 4 0 0 4 4 4 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EEQ75806.1 - 2.2e-23 82.2 1.6 2.2e-23 82.2 1.1 4.7 4 0 0 4 4 4 1 PHD-like zinc-binding domain BAH PF01426.13 EEQ75806.1 - 1.5e-16 60.2 0.0 3.6e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 EEQ75806.1 - 6.3e-11 41.8 51.1 1e-06 28.2 4.4 5.8 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.1 EEQ75806.1 - 1.3e-07 30.7 5.2 1.3e-07 30.7 3.6 5.6 6 0 0 6 6 6 1 PHD-finger Prok-RING_1 PF14446.1 EEQ75806.1 - 0.01 15.5 35.9 0.053 13.2 3.8 5.0 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 DUF1524 PF07510.6 EEQ75807.1 - 1.4e-12 47.6 0.0 1.7e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.1 EEQ75807.1 - 0.0078 15.8 0.4 0.023 14.3 0.2 1.8 1 1 0 1 1 1 1 HNH endonuclease GH-E PF14410.1 EEQ75807.1 - 0.043 13.9 0.0 0.13 12.4 0.0 1.7 2 0 0 2 2 2 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Toxin_14 PF07829.6 EEQ75810.1 - 0.59 9.9 2.1 28 4.5 0.0 2.4 2 0 0 2 2 2 0 Alpha-A conotoxin PIVA-like protein Vps8 PF12816.2 EEQ75812.1 - 1.7e-71 239.5 0.0 3.7e-71 238.4 0.0 1.6 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EEQ75812.1 - 8.5e-08 31.9 0.1 0.0046 16.5 0.0 3.7 3 0 0 3 3 3 2 Region in Clathrin and VPS Glyco_transf_90 PF05686.7 EEQ75815.1 - 2.5e-11 42.9 0.8 0.034 12.8 0.0 4.1 3 1 0 3 3 3 3 Glycosyl transferase family 90 NMN_transporter PF04973.7 EEQ75815.1 - 3.7e-05 23.2 5.0 3.7e-05 23.2 3.5 2.2 2 0 0 2 2 2 1 Nicotinamide mononucleotide transporter TctB PF07331.6 EEQ75815.1 - 0.00023 20.8 6.4 0.2 11.3 0.0 3.2 3 1 0 3 3 3 2 Tripartite tricarboxylate transporter TctB family GNAT_acetyltr_2 PF13718.1 EEQ75816.1 - 6e-79 263.9 0.0 1e-78 263.1 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EEQ75816.1 - 1.7e-64 216.7 0.0 5.8e-64 214.9 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 EEQ75816.1 - 8.5e-41 137.5 0.0 2.1e-40 136.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EEQ75816.1 - 2.2e-35 120.7 0.2 6.3e-35 119.3 0.2 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain Spore_III_AB PF09548.5 EEQ75816.1 - 0.0096 15.6 1.7 3.5 7.3 0.1 3.3 3 0 0 3 3 3 1 Stage III sporulation protein AB (spore_III_AB) Acetyltransf_7 PF13508.1 EEQ75816.1 - 0.031 14.4 0.0 0.093 12.9 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEQ75816.1 - 0.038 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Thioredoxin PF00085.15 EEQ75817.1 - 7.8e-33 112.2 0.1 5.3e-26 90.3 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EEQ75817.1 - 1.9e-09 37.7 4.8 3.2e-06 27.3 0.1 2.9 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_6 PF13848.1 EEQ75817.1 - 1.2e-07 31.7 0.0 2.8e-07 30.5 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EEQ75817.1 - 1.7e-07 31.2 0.1 2.8e-05 24.1 0.1 3.1 2 1 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 EEQ75817.1 - 0.002 17.7 0.1 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.1 EEQ75817.1 - 0.014 15.2 0.0 0.31 10.8 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin domain HTH_6 PF01418.12 EEQ75817.1 - 0.014 15.0 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Thioredoxin_7 PF13899.1 EEQ75817.1 - 0.029 14.3 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.1 EEQ75817.1 - 0.063 12.8 0.0 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin ERp29_N PF07912.8 EEQ75817.1 - 0.11 12.4 0.0 0.85 9.5 0.0 2.1 2 0 0 2 2 2 0 ERp29, N-terminal domain TraF PF13728.1 EEQ75817.1 - 0.24 10.8 0.0 0.24 10.8 0.0 3.5 4 0 0 4 4 2 0 F plasmid transfer operon protein ATP-synt PF00231.14 EEQ75820.1 - 5.4e-71 239.3 6.1 6.2e-71 239.1 4.2 1.0 1 0 0 1 1 1 1 ATP synthase Topoisom_I_N PF02919.10 EEQ75821.1 - 3.1e-98 327.3 0.7 3.1e-98 327.3 0.5 3.4 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EEQ75821.1 - 1.1e-84 283.1 4.4 1.1e-84 283.1 3.0 1.9 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EEQ75821.1 - 9.9e-33 111.6 0.4 3.2e-32 110.0 0.3 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 EEQ75821.1 - 0.03 13.4 0.1 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 RolB/RolC glucosidase family BAGE PF08180.6 EEQ75821.1 - 8 6.3 6.6 2.5 7.9 0.2 2.9 3 0 0 3 3 3 0 B melanoma antigen family Epimerase PF01370.16 EEQ75822.1 - 2.9e-23 82.5 0.0 3.8e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EEQ75822.1 - 1.2e-08 34.2 0.0 2.1e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EEQ75822.1 - 6.8e-08 31.5 0.0 1.7e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EEQ75822.1 - 3.1e-05 23.9 0.0 5.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EEQ75822.1 - 5.8e-05 23.1 0.0 0.00026 21.0 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EEQ75822.1 - 0.0019 17.2 0.0 0.011 14.7 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein MutS_V PF00488.16 EEQ75823.1 - 5.8e-89 297.5 0.0 9.2e-89 296.8 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EEQ75823.1 - 1e-39 136.4 0.6 1.8e-39 135.6 0.4 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EEQ75823.1 - 2.2e-26 92.0 0.0 6.7e-26 90.5 0.0 1.9 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EEQ75823.1 - 3.2e-08 33.7 0.0 1.3e-07 31.8 0.0 2.1 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EEQ75823.1 - 8.4e-06 25.8 0.1 4.2e-05 23.6 0.1 2.2 2 0 0 2 2 2 1 MutS family domain IV Ribosomal_S28e PF01200.13 EEQ75824.1 - 1.1e-32 111.5 1.3 1.2e-32 111.4 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e HisG PF01634.13 EEQ75825.1 - 1.6e-48 164.3 0.0 2.3e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EEQ75825.1 - 9.5e-27 92.7 0.1 1.9e-26 91.8 0.1 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 EEQ75825.1 - 0.012 15.2 0.1 0.03 13.9 0.0 1.6 1 1 0 1 1 1 0 NMT1/THI5 like DUF523 PF04463.7 EEQ75828.1 - 0.044 13.5 0.0 11 5.7 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF523) Plasmod_MYXSPDY PF07981.6 EEQ75828.1 - 0.7 9.6 2.2 19 5.0 0.1 3.1 3 0 0 3 3 3 0 Plasmodium repeat_MYXSPDY Acetyltransf_3 PF13302.1 EEQ75832.1 - 0.0088 16.2 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ApoO PF09769.4 EEQ75832.1 - 0.028 14.1 0.2 0.062 13.0 0.1 1.6 1 0 0 1 1 1 0 Apolipoprotein O HR1 PF02185.11 EEQ75832.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Hr1 repeat DMPK_coil PF08826.5 EEQ75832.1 - 0.21 11.4 1.1 0.63 9.9 0.1 2.1 2 0 0 2 2 2 0 DMPK coiled coil domain like Syntaxin-6_N PF09177.6 EEQ75832.1 - 0.26 11.6 1.6 1.2 9.5 1.2 2.1 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Uds1 PF15456.1 EEQ75832.1 - 0.89 9.5 4.2 0.37 10.7 0.9 1.8 2 0 0 2 2 2 0 Up-regulated During Septation Dicty_REP PF05086.7 EEQ75833.1 - 1.6 6.3 11.2 2.5 5.7 7.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pex14_N PF04695.8 EEQ75833.1 - 4.6 7.3 7.0 2.4 8.2 2.4 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Carb_anhydrase PF00194.16 EEQ75834.1 - 9.4e-28 96.8 0.6 1.4e-27 96.2 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Peptidase_C48 PF02902.14 EEQ75835.1 - 4e-15 56.0 0.2 1.3e-14 54.3 0.1 1.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RhoGEF PF00621.15 EEQ75837.1 - 9e-40 136.4 0.0 1.7e-39 135.5 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 EEQ75837.1 - 6.5e-07 29.0 1.9 9.8e-07 28.5 0.2 2.2 2 1 0 2 2 2 1 BAR domain RabGAP-TBC PF00566.13 EEQ75838.1 - 8.2e-16 58.1 0.0 5.5e-14 52.1 0.0 2.4 1 1 1 2 2 2 2 Rab-GTPase-TBC domain DUF3853 PF12964.2 EEQ75838.1 - 0.13 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) Proteasome PF00227.21 EEQ75839.1 - 6.5e-44 149.4 0.1 7.4e-44 149.3 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Abhydrolase_5 PF12695.2 EEQ75840.1 - 5.9e-21 74.7 0.0 8.8e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ75840.1 - 1.6e-16 60.9 0.0 6.6e-15 55.6 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EEQ75840.1 - 1.2e-06 28.1 0.0 3.3e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 EEQ75840.1 - 1.8e-06 27.3 0.0 6e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 EEQ75840.1 - 7.4e-06 24.6 0.1 0.2 10.1 0.0 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 EEQ75840.1 - 1.5e-05 24.5 0.1 0.16 11.4 0.0 2.5 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EEQ75840.1 - 0.00021 20.9 0.0 0.013 15.1 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.6 EEQ75840.1 - 0.0013 18.5 0.0 0.13 11.9 0.0 2.2 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.8 EEQ75840.1 - 0.0015 18.2 0.1 0.0058 16.2 0.1 1.8 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 EEQ75840.1 - 0.0023 17.7 0.0 0.0077 16.0 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S15 PF02129.13 EEQ75840.1 - 0.0023 17.3 0.0 0.54 9.6 0.0 2.4 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 EEQ75840.1 - 0.0041 16.4 0.0 0.73 9.0 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF2305 PF10230.4 EEQ75840.1 - 0.0074 15.7 0.0 0.042 13.2 0.0 1.8 1 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) DUF1057 PF06342.7 EEQ75840.1 - 0.012 14.4 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF818 PF05677.7 EEQ75840.1 - 0.035 12.8 0.0 0.049 12.3 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Abhydrolase_3 PF07859.8 EEQ75840.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S28 PF05577.7 EEQ75840.1 - 0.11 11.0 0.0 0.21 10.1 0.0 1.4 1 1 0 1 1 1 0 Serine carboxypeptidase S28 ATP11 PF06644.6 EEQ75841.1 - 9.2e-85 284.3 0.0 1.1e-84 284.1 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein TMEM240 PF15207.1 EEQ75842.1 - 0.024 14.2 0.0 0.026 14.1 0.0 1.1 1 0 0 1 1 1 0 TMEM240 family 2-Hacid_dh_C PF02826.14 EEQ75843.1 - 2.1e-56 189.8 0.0 3.7e-56 189.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEQ75843.1 - 1.4e-28 99.0 0.1 2.2e-28 98.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 EEQ75843.1 - 0.0018 18.1 0.1 0.0048 16.7 0.0 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.10 EEQ75843.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 EEQ75843.1 - 0.083 12.8 0.5 0.18 11.8 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain F420_oxidored PF03807.12 EEQ75843.1 - 0.099 13.0 0.1 0.31 11.5 0.1 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Cyclin PF08613.6 EEQ75844.1 - 4.6e-38 130.9 7.2 1.8e-22 80.3 0.2 2.7 3 0 0 3 3 3 2 Cyclin Pkinase PF00069.20 EEQ75846.1 - 5.9e-35 120.6 0.0 8.5e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ75846.1 - 2.9e-12 46.2 0.0 9.8e-06 24.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase CAMSAP_CH PF11971.3 EEQ75847.1 - 0.0013 18.3 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 2 CAMSAP CH domain CH PF00307.26 EEQ75847.1 - 0.003 17.6 0.0 2.1 8.4 0.0 3.2 2 1 0 2 2 2 2 Calponin homology (CH) domain Vezatin PF12632.2 EEQ75848.1 - 1.1e-53 181.9 0.1 1.7e-53 181.2 0.1 1.4 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes Polysacc_synt_C PF14667.1 EEQ75848.1 - 0.0009 19.0 0.9 0.0014 18.4 0.6 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain Borrelia_lipo_1 PF05714.6 EEQ75848.1 - 0.1 11.6 0.1 0.2 10.7 0.1 1.4 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein DUF2648 PF10855.3 EEQ75848.1 - 0.19 11.1 0.5 0.38 10.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) PCNA_N PF00705.13 EEQ75849.1 - 4.1e-55 184.7 3.7 4.1e-55 184.7 2.5 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EEQ75849.1 - 3e-48 162.9 0.0 7.9e-48 161.5 0.0 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EEQ75849.1 - 1.9e-08 33.7 0.1 2.3e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 EEQ75849.1 - 0.00056 18.9 0.4 0.0055 15.6 0.1 2.0 1 1 1 2 2 2 1 Hus1-like protein Zn_clus PF00172.13 EEQ75850.1 - 7e-08 32.2 10.9 1.3e-07 31.3 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-B_box PF00643.19 EEQ75850.1 - 2.1 8.2 8.8 5 7.0 6.1 1.5 1 0 0 1 1 1 0 B-box zinc finger PrkA PF06798.7 EEQ75851.1 - 0.007 15.6 7.5 0.0075 15.5 5.2 1.1 1 0 0 1 1 1 1 PrkA serine protein kinase C-terminal domain GIDA_assoc_3 PF13932.1 EEQ75851.1 - 0.055 13.5 0.6 0.095 12.7 0.4 1.5 1 0 0 1 1 1 0 GidA associated domain 3 Gp_dh_N PF00044.19 EEQ75851.1 - 0.081 12.8 1.6 0.091 12.7 1.1 1.1 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain tRNA_lig_CPD PF08302.6 EEQ75851.1 - 0.14 11.3 6.2 0.017 14.3 1.4 1.5 1 1 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain DUF3074 PF11274.3 EEQ75851.1 - 1.3 8.5 4.9 1.6 8.3 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) RCR PF12273.3 EEQ75853.1 - 0.002 18.6 1.7 0.033 14.7 0.1 2.5 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red p450 PF00067.17 EEQ75854.1 - 3e-53 180.9 0.0 4.1e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sec61_beta PF03911.11 EEQ75855.1 - 1.6e-19 69.4 1.0 2.1e-19 69.0 0.7 1.2 1 0 0 1 1 1 1 Sec61beta family DUF4139 PF13598.1 EEQ75856.1 - 2.1e-50 171.8 0.1 3.6e-38 131.6 0.0 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 EEQ75856.1 - 2.9e-12 46.9 0.2 2.9e-12 46.9 0.2 4.7 5 2 1 6 6 6 1 N-terminal domain of unknown function (DUF4140) BAF1_ABF1 PF04684.8 EEQ75856.1 - 0.005 15.7 13.3 0.005 15.7 9.2 1.9 2 0 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor RepL PF05732.6 EEQ75856.1 - 0.049 12.8 1.8 0.093 11.9 1.3 1.3 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) DUF2951 PF11166.3 EEQ75856.1 - 5.4 6.9 8.2 2.1 8.2 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) RecR PF02132.10 EEQ75857.1 - 0.18 11.2 1.1 1.4 8.4 0.1 2.2 2 0 0 2 2 2 0 RecR protein Dynein_light PF01221.13 EEQ75858.1 - 5.3e-41 138.4 2.6 6.3e-41 138.2 1.8 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DUF950 PF06106.6 EEQ75858.1 - 0.034 14.2 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 Staphylococcus protein of unknown function (DUF950) RNase_E_G PF10150.4 EEQ75858.1 - 0.046 12.9 0.2 0.054 12.7 0.1 1.1 1 0 0 1 1 1 0 Ribonuclease E/G family Ribosomal_L6e PF01159.14 EEQ75858.1 - 0.07 13.3 0.4 0.087 13.0 0.3 1.1 1 0 0 1 1 1 0 Ribosomal protein L6e Viral_DNA_bp PF00747.12 EEQ75858.1 - 0.072 10.3 0.0 0.073 10.2 0.0 1.0 1 0 0 1 1 1 0 ssDNA binding protein DUF3139 PF11337.3 EEQ75858.1 - 0.092 13.0 0.3 0.15 12.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) SpoIIIAH PF12685.2 EEQ75858.1 - 1.3 8.4 6.0 1.7 8.1 4.2 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein RRM_1 PF00076.17 EEQ75859.1 - 6.3e-75 246.7 1.7 1.1e-19 69.8 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ75859.1 - 3.9e-64 212.5 0.7 1.6e-15 56.7 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ75859.1 - 4.4e-36 122.5 0.1 1e-11 44.5 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EEQ75859.1 - 5.3e-06 26.1 0.3 0.11 12.2 0.0 4.6 4 0 0 4 4 4 1 Limkain b1 Nup35_RRM_2 PF14605.1 EEQ75859.1 - 1.3e-05 24.8 0.0 0.071 12.8 0.0 3.7 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 EEQ75859.1 - 0.00059 19.7 0.3 7.2 6.6 0.0 4.5 4 1 1 5 5 5 1 RNA binding domain Aldo_ket_red PF00248.16 EEQ75860.1 - 1e-34 119.7 0.0 1.2e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family R3H-assoc PF13902.1 EEQ75861.1 - 0.11 12.4 2.1 0.088 12.7 0.5 1.8 2 1 0 2 2 2 0 R3H-associated N-terminal domain LRR_4 PF12799.2 EEQ75862.1 - 2.4e-41 138.7 32.6 4.5e-11 42.0 1.5 7.0 4 2 5 9 9 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEQ75862.1 - 7.6e-23 80.0 27.4 1e-08 34.7 3.5 4.8 2 1 2 4 4 4 4 Leucine rich repeat LRR_7 PF13504.1 EEQ75862.1 - 8.9e-15 52.2 14.6 0.48 10.8 0.1 10.0 10 0 0 10 10 10 3 Leucine rich repeat LRR_1 PF00560.28 EEQ75862.1 - 3.1e-14 50.8 28.0 0.055 13.5 0.5 10.7 11 0 0 11 11 11 5 Leucine Rich Repeat LRR_9 PF14580.1 EEQ75862.1 - 2.2e-12 46.8 11.8 8.1e-07 28.7 2.1 3.3 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.1 EEQ75862.1 - 1.6e-11 43.0 25.2 0.038 14.0 0.2 9.4 8 2 2 10 10 10 4 Leucine Rich repeat DUF3744 PF12558.3 EEQ75862.1 - 2.7 8.5 10.4 13 6.2 0.3 4.3 2 1 3 5 5 5 0 ATP-binding cassette cobalt transporter NIF PF03031.13 EEQ75863.1 - 1.8e-51 173.9 0.3 2.5e-51 173.4 0.2 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ABC_membrane_2 PF06472.10 EEQ75865.1 - 7e-96 320.6 0.2 1.3e-95 319.8 0.0 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EEQ75865.1 - 1e-13 51.7 0.0 2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EEQ75865.1 - 0.033 13.7 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EEQ75865.1 - 0.033 14.1 0.0 0.074 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 EEQ75865.1 - 0.041 14.0 0.0 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEQ75865.1 - 0.047 14.5 0.1 0.44 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EEQ75865.1 - 0.072 13.4 0.2 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 EEQ75865.1 - 0.12 11.4 0.0 0.33 9.9 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EEQ75865.1 - 0.13 11.3 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EEQ75865.1 - 0.17 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain p450 PF00067.17 EEQ75866.1 - 1.2e-20 73.5 0.0 4e-11 42.1 0.0 2.8 3 0 0 3 3 3 2 Cytochrome P450 Clr2 PF10383.4 EEQ75867.1 - 1.5e-36 125.4 0.0 2.4e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 Toxin_22 PF08092.6 EEQ75867.1 - 7.5 6.4 6.7 4.7 7.1 0.1 3.4 4 0 0 4 4 4 0 Magi peptide toxin family 2OG-FeII_Oxy PF03171.15 EEQ75868.1 - 0.00037 20.7 0.0 0.0013 18.9 0.0 2.0 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily SAD_SRA PF02182.12 EEQ75869.1 - 9.8e-21 73.6 0.0 1.5e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 SAD/SRA domain CLTH PF10607.4 EEQ75870.1 - 1.1e-32 112.7 0.0 2.2e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EEQ75870.1 - 7.7e-19 67.1 0.9 2.7e-18 65.3 0.6 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EEQ75870.1 - 9.7e-05 22.1 0.4 0.00018 21.2 0.3 1.5 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.7 EEQ75870.1 - 0.00012 21.4 0.0 0.00024 20.4 0.0 1.5 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.1 EEQ75870.1 - 0.00016 21.3 0.2 0.00028 20.5 0.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEQ75870.1 - 0.0024 17.8 0.7 0.0043 17.0 0.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ75870.1 - 0.013 15.1 0.5 0.022 14.4 0.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) LURAP PF14854.1 EEQ75870.1 - 0.03 14.0 0.2 5.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Leucine rich adaptor protein zf-C3HC4_4 PF15227.1 EEQ75870.1 - 0.043 13.6 1.0 0.11 12.4 0.7 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EEQ75870.1 - 0.16 11.6 0.7 0.34 10.6 0.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PG_binding_1 PF01471.13 EEQ75871.1 - 0.0033 17.3 0.1 0.9 9.5 0.0 3.3 2 1 0 2 2 2 2 Putative peptidoglycan binding domain zf-Tim10_DDP PF02953.10 EEQ75872.1 - 4.2e-24 83.6 3.2 5.2e-24 83.3 2.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger tRNA-synt_2 PF00152.15 EEQ75873.1 - 1.4e-67 227.8 0.0 1.1e-37 129.6 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EEQ75873.1 - 3.9e-08 33.0 0.0 9.2e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain APH PF01636.18 EEQ75875.1 - 8.3e-05 22.4 0.5 0.00011 21.9 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family HicB PF05534.7 EEQ75875.1 - 0.062 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 HicB family DUF4135 PF13575.1 EEQ75875.1 - 0.18 10.8 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) BTB PF00651.26 EEQ75877.1 - 1e-06 28.6 0.0 4.7e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.10 EEQ75877.1 - 0.14 12.3 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain DUF4570 PF15134.1 EEQ75878.1 - 0.03 14.1 0.2 0.049 13.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) Septin PF00735.13 EEQ75879.1 - 8.5e-112 372.7 0.3 1e-111 372.4 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EEQ75879.1 - 2e-06 27.7 0.0 3.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EEQ75879.1 - 6.5e-06 25.4 0.0 1.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EEQ75879.1 - 5.4e-05 22.4 0.0 0.0001 21.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EEQ75879.1 - 0.00064 19.5 0.4 1.4 8.7 0.0 2.4 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 EEQ75879.1 - 0.00078 18.9 0.2 0.014 14.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 EEQ75879.1 - 0.0052 16.2 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_23 PF13476.1 EEQ75879.1 - 0.0094 16.2 0.0 0.018 15.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEQ75879.1 - 0.011 15.8 0.0 0.028 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EEQ75879.1 - 0.012 15.9 0.2 0.019 15.2 0.1 1.6 1 1 0 1 1 1 0 ABC transporter T2SE PF00437.15 EEQ75879.1 - 0.028 13.3 0.0 0.082 11.7 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.17 EEQ75879.1 - 0.033 13.0 0.0 0.058 12.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 EEQ75879.1 - 0.034 13.6 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EEQ75879.1 - 0.036 14.0 0.0 0.066 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.7 EEQ75879.1 - 0.075 12.1 0.1 0.21 10.7 0.0 1.8 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.2 EEQ75879.1 - 0.13 11.2 0.0 13 4.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region D3 AAA_29 PF13555.1 EEQ75879.1 - 0.16 11.5 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain WD40 PF00400.27 EEQ75880.1 - 5.8e-27 92.5 18.2 8.5e-13 47.6 0.8 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Ribosomal_L32p PF01783.18 EEQ75880.1 - 2.5e-11 43.5 4.9 2.5e-11 43.5 3.4 1.7 2 0 0 2 2 2 1 Ribosomal L32p protein family eIF2A PF08662.6 EEQ75880.1 - 0.00067 19.4 0.0 0.0021 17.8 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EEQ75880.1 - 0.043 12.9 0.7 3.4 6.6 0.0 3.1 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Spindle_Spc25 PF08234.7 EEQ75881.1 - 1.4e-21 76.2 0.2 3.9e-21 74.8 0.0 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 DUF4614 PF15391.1 EEQ75881.1 - 0.0034 17.1 3.2 0.0047 16.7 0.3 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4614) Zeta_toxin PF06414.7 EEQ75881.1 - 0.018 14.1 2.3 0.025 13.6 1.6 1.2 1 0 0 1 1 1 0 Zeta toxin Mnd1 PF03962.10 EEQ75881.1 - 2 8.0 13.4 0.28 10.8 2.9 2.1 1 1 1 2 2 2 0 Mnd1 family DUF3053 PF11254.3 EEQ75881.1 - 2.6 7.2 10.6 1.1 8.4 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) Rrn6 PF10214.4 EEQ75882.1 - 4.6e-66 223.4 42.2 3e-44 151.3 0.0 4.8 3 1 1 4 4 4 3 RNA polymerase I-specific transcription-initiation factor F-112 PF09645.5 EEQ75882.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 F-112 protein zinc_ribbon_6 PF14599.1 EEQ75883.1 - 1.9e-25 88.3 0.8 1.9e-25 88.3 0.6 3.8 4 0 0 4 4 4 1 Zinc-ribbon zf-CHY PF05495.7 EEQ75883.1 - 1.7e-14 53.7 23.3 1.7e-14 53.7 16.2 4.4 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.1 EEQ75883.1 - 1.8e-08 34.0 9.3 1.8e-08 34.0 6.4 4.3 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEQ75883.1 - 6.2e-08 32.1 6.8 6.2e-08 32.1 4.7 5.6 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ75883.1 - 5e-07 29.6 7.8 5e-07 29.6 5.4 5.5 4 2 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ75883.1 - 1.1e-05 25.1 8.9 1.1e-05 25.1 6.2 6.4 5 4 1 6 6 6 1 zinc-RING finger domain Complex1_LYR PF05347.10 EEQ75884.1 - 5.3e-10 38.9 0.1 7.9e-10 38.3 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EEQ75884.1 - 0.0023 18.1 0.3 0.0041 17.3 0.2 1.5 1 1 0 1 1 1 1 Complex1_LYR-like LssY_C PF14067.1 EEQ75884.1 - 0.11 11.4 0.1 0.23 10.4 0.0 1.5 2 0 0 2 2 2 0 LssY C-terminus DUF2293 PF10056.4 EEQ75885.1 - 1.2e-27 95.7 0.2 2.4e-27 94.7 0.2 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) HMA PF00403.21 EEQ75886.1 - 6.4e-17 61.4 0.2 7.9e-17 61.1 0.2 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain zf-RING_2 PF13639.1 EEQ75887.1 - 4.8e-05 23.0 11.4 0.00031 20.5 7.9 2.0 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EEQ75887.1 - 0.00073 19.5 6.5 0.0015 18.6 4.5 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger HECA PF15353.1 EEQ75887.1 - 0.0076 15.9 1.1 0.0087 15.7 0.8 1.2 1 0 0 1 1 1 1 Headcase protein family homologue zf-RING_5 PF14634.1 EEQ75887.1 - 0.019 14.7 5.0 0.076 12.7 3.5 2.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-Apc11 PF12861.2 EEQ75887.1 - 0.072 12.9 7.6 0.32 10.8 5.3 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EEQ75887.1 - 0.074 13.0 7.9 0.23 11.4 5.5 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4 PF00097.20 EEQ75887.1 - 0.12 12.1 3.2 0.66 9.6 2.4 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 EEQ75887.1 - 0.16 11.7 9.1 0.19 11.4 1.0 2.8 1 1 2 3 3 3 0 Prokaryotic RING finger family 1 PHD PF00628.24 EEQ75887.1 - 5.2 6.8 8.9 62 3.4 6.0 2.6 1 1 1 2 2 2 0 PHD-finger zf-C3HC4_3 PF13920.1 EEQ75887.1 - 5.3 6.8 10.7 55 3.5 7.4 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ75887.1 - 9.8 6.3 12.5 64 3.6 0.1 2.7 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) PCI PF01399.22 EEQ75888.1 - 1.7e-08 34.7 0.0 3.7e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 PCI domain DUF433 PF04255.9 EEQ75888.1 - 0.0015 17.9 0.0 0.0032 16.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF433) TPR_2 PF07719.12 EEQ75888.1 - 0.06 13.2 0.2 0.18 11.8 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Ribosomal_L18ae PF01775.12 EEQ75889.1 - 4e-27 94.5 0.7 5.5e-27 94.1 0.5 1.2 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain NAD_binding_1 PF00175.16 EEQ75890.1 - 1.1e-29 103.2 0.0 1.7e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EEQ75890.1 - 2.8e-13 49.8 0.0 6e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EEQ75890.1 - 1.3e-09 38.1 0.0 2.8e-05 24.0 0.0 2.8 3 0 0 3 3 3 2 Ferric reductase NAD binding domain AAR2 PF05282.6 EEQ75890.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 AAR2 protein HMG_box PF00505.14 EEQ75892.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box DUF1841 PF08897.6 EEQ75895.1 - 0.16 11.7 0.6 0.35 10.7 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) AAA PF00004.24 EEQ75896.1 - 2.4e-15 56.8 0.0 3.5e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEQ75896.1 - 7e-05 22.8 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EEQ75896.1 - 0.00013 22.7 0.0 0.00073 20.3 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 EEQ75896.1 - 0.00032 20.4 0.0 0.00063 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EEQ75896.1 - 0.0018 17.7 0.0 0.003 16.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 EEQ75896.1 - 0.0027 17.8 0.0 0.013 15.6 0.0 1.9 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EEQ75896.1 - 0.0085 15.2 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EEQ75896.1 - 0.0086 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EEQ75896.1 - 0.012 15.7 0.0 0.071 13.2 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.1 EEQ75896.1 - 0.015 15.0 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain RuvB_N PF05496.7 EEQ75896.1 - 0.026 13.5 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EEQ75896.1 - 0.13 12.5 0.2 0.27 11.5 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EEQ75896.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mif2_N PF15624.1 EEQ75898.1 - 1.2 9.7 10.9 0.93 10.0 2.3 3.2 2 1 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal SLAC1 PF03595.12 EEQ75899.1 - 7.4e-74 248.3 48.4 8.6e-74 248.1 33.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel ABC1 PF03109.11 EEQ75900.1 - 2.6e-23 82.2 0.0 3.3e-13 49.6 0.0 2.5 1 1 1 2 2 2 2 ABC1 family APH PF01636.18 EEQ75900.1 - 0.011 15.5 0.1 0.035 13.8 0.1 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EEQ75900.1 - 0.027 13.8 0.0 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 RIO1 family HA2 PF04408.18 EEQ75901.1 - 1.5e-12 47.4 0.0 1.5e-12 47.4 0.0 2.7 2 1 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EEQ75901.1 - 0.0018 18.0 0.0 0.011 15.6 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DUF676 PF05057.9 EEQ75902.1 - 0.0033 16.7 0.1 0.005 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EEQ75902.1 - 0.016 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 EEQ75902.1 - 0.018 14.9 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 EEQ75902.1 - 0.032 13.8 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF900 PF05990.7 EEQ75902.1 - 0.091 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Tox-ART-HYE1 PF15634.1 EEQ75902.1 - 0.2 10.5 0.0 0.31 9.9 0.0 1.1 1 0 0 1 1 1 0 HYE1 signature containing ADP-ribosyltransferase Cyto_heme_lyase PF01265.12 EEQ75903.1 - 1.2e-76 257.7 0.0 1.7e-76 257.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Fungal_trans_2 PF11951.3 EEQ75904.1 - 2.3e-06 26.4 0.0 5.1e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain FTA2 PF13095.1 EEQ75905.1 - 1.1e-35 123.0 0.2 1.9e-35 122.3 0.1 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 UQ_con PF00179.21 EEQ75907.1 - 3.7e-26 91.2 0.1 5e-26 90.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bac_surface_Ag PF01103.18 EEQ75908.1 - 2.4e-41 142.2 0.1 3.8e-41 141.6 0.0 1.3 1 0 0 1 1 1 1 Surface antigen YkyA PF10368.4 EEQ75908.1 - 0.11 11.8 0.5 0.16 11.3 0.4 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Yip1 PF04893.12 EEQ75909.1 - 2.9e-05 23.6 16.2 0.0008 18.9 6.0 2.4 2 0 0 2 2 2 2 Yip1 domain UFD1 PF03152.9 EEQ75910.1 - 1.4e-26 92.7 0.0 2.2e-20 72.5 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 IBR PF01485.16 EEQ75911.1 - 3.5e-13 49.2 14.9 1.1e-09 37.9 2.3 3.8 3 1 0 3 3 3 2 IBR domain Ribosomal_S27 PF01599.14 EEQ75911.1 - 0.49 10.2 14.7 4.3 7.2 4.2 3.8 3 1 0 3 3 3 0 Ribosomal protein S27a F-box-like PF12937.2 EEQ75912.1 - 0.00015 21.4 0.1 0.00042 19.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ75912.1 - 0.00051 19.6 0.6 0.0032 17.0 0.4 2.4 2 0 0 2 2 2 1 F-box domain FGGY_C PF02782.11 EEQ75914.1 - 6.2e-53 179.3 0.1 9.5e-53 178.7 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EEQ75914.1 - 6.7e-25 87.8 0.0 1.4e-23 83.4 0.0 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 EEQ75914.1 - 0.019 14.2 0.1 0.11 11.8 0.0 2.0 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Na_Ca_ex PF01699.19 EEQ75915.1 - 5.4e-32 110.3 22.6 8.7e-20 70.7 5.7 3.9 6 0 0 6 6 6 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EEQ75915.1 - 1.7e-14 53.9 7.2 1.7e-14 53.9 5.0 3.6 2 0 0 2 2 2 1 Domain of unknown function (DUF307) AAA PF00004.24 EEQ75916.1 - 7e-44 149.2 0.0 1.1e-43 148.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EEQ75916.1 - 1.7e-07 31.2 0.0 3.3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EEQ75916.1 - 3.5e-07 30.0 0.0 9.2e-07 28.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EEQ75916.1 - 1.6e-06 28.1 0.0 3.4e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEQ75916.1 - 4.2e-06 26.9 0.1 0.00021 21.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ75916.1 - 4.8e-05 23.0 0.1 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EEQ75916.1 - 8.1e-05 23.4 0.0 0.00018 22.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEQ75916.1 - 9.1e-05 21.6 0.0 0.00016 20.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EEQ75916.1 - 0.00011 21.6 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EEQ75916.1 - 0.001 17.9 0.0 0.0018 17.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EEQ75916.1 - 0.0015 18.3 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEQ75916.1 - 0.0018 18.1 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEQ75916.1 - 0.0025 16.9 0.0 0.0044 16.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 EEQ75916.1 - 0.0039 16.7 0.0 0.012 15.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EEQ75916.1 - 0.004 17.1 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EEQ75916.1 - 0.0067 15.5 0.0 0.016 14.2 0.0 1.6 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.16 EEQ75916.1 - 0.0071 15.5 0.1 0.015 14.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EEQ75916.1 - 0.0095 16.2 0.1 0.047 13.9 0.0 2.3 3 0 0 3 3 2 1 AAA domain DUF815 PF05673.8 EEQ75916.1 - 0.015 14.2 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.11 EEQ75916.1 - 0.016 14.4 0.0 0.052 12.7 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.21 EEQ75916.1 - 0.018 14.5 0.0 0.086 12.3 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_25 PF13481.1 EEQ75916.1 - 0.018 14.4 0.1 0.079 12.3 0.0 1.8 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EEQ75916.1 - 0.024 14.2 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EEQ75916.1 - 0.041 14.0 0.0 0.075 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 EEQ75916.1 - 0.056 13.4 0.0 0.15 12.1 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 EEQ75916.1 - 0.067 12.8 0.0 0.37 10.4 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 EEQ75916.1 - 0.075 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EEQ75916.1 - 0.092 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2072 PF09845.4 EEQ75916.1 - 0.095 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Histone PF00125.19 EEQ75916.1 - 0.097 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 F-box-like PF12937.2 EEQ75918.1 - 0.0094 15.6 0.2 0.026 14.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ75918.1 - 0.042 13.5 0.0 0.085 12.5 0.0 1.5 1 0 0 1 1 1 0 F-box domain PNMA PF14893.1 EEQ75919.1 - 0.05 12.6 0.2 0.061 12.3 0.1 1.2 1 0 0 1 1 1 0 PNMA ABC_tran PF00005.22 EEQ75920.1 - 9.1e-25 87.5 8.6 4.2e-12 46.5 0.1 3.9 4 0 0 4 4 4 3 ABC transporter AAA_21 PF13304.1 EEQ75920.1 - 2.7e-08 34.1 4.5 0.0055 16.7 0.0 3.2 3 0 0 3 3 3 3 AAA domain ABC_tran_2 PF12848.2 EEQ75920.1 - 1.8e-06 27.6 0.7 1.8e-06 27.6 0.5 2.2 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EEQ75920.1 - 0.00095 18.4 1.5 1.9 7.6 0.0 3.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 EEQ75920.1 - 0.0058 16.5 0.7 0.31 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EEQ75920.1 - 0.024 14.5 0.1 0.091 12.7 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 EEQ75920.1 - 0.036 14.5 0.0 0.079 13.4 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 EEQ75920.1 - 0.047 14.0 2.0 0.11 12.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EEQ75920.1 - 0.047 14.4 1.8 0.12 13.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EEQ75920.1 - 0.051 13.2 0.1 0.15 11.7 0.1 1.8 2 0 0 2 2 2 0 NACHT domain MobB PF03205.9 EEQ75920.1 - 0.08 12.6 0.2 0.24 11.0 0.1 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Thymidylate_kin PF02223.12 EEQ75920.1 - 0.12 11.7 1.1 0.32 10.3 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA_29 PF13555.1 EEQ75920.1 - 0.12 11.8 0.1 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Y_phosphatase PF00102.22 EEQ75921.1 - 2.4e-58 197.2 0.6 1.4e-32 112.9 0.0 3.3 3 1 0 3 3 3 2 Protein-tyrosine phosphatase Rhodanese PF00581.15 EEQ75921.1 - 6e-11 42.7 0.0 1.8e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain DSPc PF00782.15 EEQ75921.1 - 0.012 15.2 0.1 0.027 14.0 0.1 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EEQ75921.1 - 0.014 15.6 0.0 0.035 14.3 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family COX16 PF14138.1 EEQ75922.1 - 1.6e-30 105.0 0.1 2.2e-30 104.6 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Nic96 PF04097.9 EEQ75923.1 - 3e-217 722.5 0.0 3.7e-217 722.3 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 RibD_C PF01872.12 EEQ75924.1 - 1.9e-30 105.9 0.0 4.7e-30 104.6 0.0 1.7 1 0 0 1 1 1 1 RibD C-terminal domain RCC1 PF00415.13 EEQ75926.1 - 2.5e-51 171.6 17.6 2.3e-11 43.7 0.1 8.0 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EEQ75926.1 - 6.4e-29 98.9 38.2 4.3e-07 29.3 0.7 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat SUKH_5 PF14567.1 EEQ75926.1 - 0.078 12.4 0.0 1.8 8.0 0.0 2.6 2 1 1 3 3 3 0 SMI1-KNR4 cell-wall Swi3 PF07962.7 EEQ75927.1 - 4.4e-31 106.3 0.1 7.1e-31 105.6 0.1 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 SOG2 PF10428.4 EEQ75927.1 - 1.1 7.8 6.8 0.065 11.8 1.1 1.5 2 0 0 2 2 2 0 RAM signalling pathway protein NADH-u_ox-rdase PF10785.4 EEQ75928.1 - 1.1e-35 121.7 0.4 1.6e-35 121.1 0.3 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 EEQ75928.1 - 2.3e-35 120.1 0.1 3.4e-35 119.6 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit dCMP_cyt_deam_1 PF00383.17 EEQ75929.1 - 1.8e-22 78.9 0.1 2.3e-22 78.5 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EEQ75929.1 - 0.0069 16.2 0.4 0.025 14.4 0.3 1.9 1 1 0 1 1 1 1 Bd3614-like deaminase PI3_PI4_kinase PF00454.22 EEQ75930.1 - 8.3e-51 172.7 0.0 1.7e-50 171.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EEQ75930.1 - 8.3e-48 163.1 0.6 2.7e-47 161.4 0.4 2.0 1 0 0 1 1 1 1 FAT domain UME PF08064.8 EEQ75930.1 - 6.7e-39 132.1 0.5 6.7e-39 132.1 0.4 2.8 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.15 EEQ75930.1 - 3.7e-15 55.0 0.0 1.2e-14 53.4 0.0 2.0 2 0 0 2 2 2 1 FATC domain TPR_14 PF13428.1 EEQ75930.1 - 0.29 11.8 4.1 19 6.2 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat RRM_1 PF00076.17 EEQ75931.1 - 1.9e-13 49.8 0.0 2.8e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ75931.1 - 9.7e-11 41.4 0.0 1.5e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ75931.1 - 1.1e-07 31.6 0.0 1.8e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.24 EEQ75932.1 - 1.3e-59 200.1 0.0 1.6e-40 138.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEQ75932.1 - 2.7e-09 37.2 3.2 0.002 18.1 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.1 EEQ75932.1 - 1.9e-07 31.0 0.0 0.0092 15.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEQ75932.1 - 3.8e-07 29.6 3.7 0.076 12.4 0.3 3.6 2 2 1 3 3 3 2 AAA domain AAA_17 PF13207.1 EEQ75932.1 - 4.3e-07 30.7 0.2 0.0049 17.6 0.1 3.0 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EEQ75932.1 - 6.4e-07 29.5 3.1 0.042 13.9 1.1 4.2 2 2 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EEQ75932.1 - 1.8e-06 27.9 0.0 0.0039 17.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EEQ75932.1 - 5e-06 26.2 2.6 0.025 14.3 0.0 3.4 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EEQ75932.1 - 5.5e-06 26.5 0.0 0.096 12.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.7 EEQ75932.1 - 9.9e-05 21.4 0.0 0.051 12.6 0.0 3.3 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EEQ75932.1 - 0.00013 20.8 0.5 0.00092 18.0 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus AAA_19 PF13245.1 EEQ75932.1 - 0.00014 21.5 0.4 2.1 8.1 0.0 3.9 3 0 0 3 3 3 2 Part of AAA domain IstB_IS21 PF01695.12 EEQ75932.1 - 0.00021 20.7 0.2 0.66 9.3 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein Arch_ATPase PF01637.13 EEQ75932.1 - 0.00059 19.6 0.0 0.17 11.5 0.0 3.1 2 1 1 3 3 3 1 Archaeal ATPase AAA_2 PF07724.9 EEQ75932.1 - 0.00093 19.1 0.0 0.0054 16.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Rad17 PF03215.10 EEQ75932.1 - 0.00099 17.8 0.1 0.023 13.4 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Mg_chelatase PF01078.16 EEQ75932.1 - 0.0012 18.0 1.3 0.057 12.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EEQ75932.1 - 0.0019 17.8 2.8 0.04 13.4 0.3 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EEQ75932.1 - 0.0025 17.5 3.6 1 8.9 0.4 3.9 2 2 1 3 3 3 1 NACHT domain Sigma54_activ_2 PF14532.1 EEQ75932.1 - 0.0029 17.6 0.0 0.95 9.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.1 EEQ75932.1 - 0.0055 16.5 0.0 0.36 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EEQ75932.1 - 0.0057 15.6 0.1 3.2 6.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Bac_DnaA PF00308.13 EEQ75932.1 - 0.0057 16.3 0.1 0.24 11.0 0.0 3.0 3 1 0 3 3 3 1 Bacterial dnaA protein AAA_29 PF13555.1 EEQ75932.1 - 0.0087 15.5 0.1 0.057 12.9 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EEQ75932.1 - 0.012 15.9 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEQ75932.1 - 0.027 14.7 0.0 0.29 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EEQ75932.1 - 0.069 13.4 1.2 1.9 8.7 0.1 2.5 2 0 0 2 2 2 0 ABC transporter DAP3 PF10236.4 EEQ75932.1 - 0.13 11.1 0.6 0.45 9.3 0.1 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Ras PF00071.17 EEQ75934.1 - 6.6e-66 220.6 0.0 7.9e-66 220.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ75934.1 - 6.3e-19 68.6 0.0 1.1e-18 67.8 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EEQ75934.1 - 1.1e-13 50.8 0.1 1.3e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEQ75934.1 - 3.1e-06 26.5 0.0 3.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EEQ75934.1 - 4.5e-06 26.2 0.1 1.8e-05 24.2 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEQ75934.1 - 0.0043 17.0 0.0 0.0083 16.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 EEQ75934.1 - 0.005 17.0 0.0 3.6 7.8 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 EEQ75934.1 - 0.024 13.9 0.0 0.15 11.3 0.0 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.1 EEQ75934.1 - 0.11 12.0 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2589 PF11655.3 EEQ75934.1 - 0.13 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2589) AAA_22 PF13401.1 EEQ75934.1 - 0.14 12.3 0.0 0.31 11.1 0.0 1.8 1 1 1 2 2 2 0 AAA domain SNF PF00209.13 EEQ75937.1 - 1e-90 304.7 36.8 1e-90 304.7 25.5 2.6 2 1 0 2 2 2 1 Sodium:neurotransmitter symporter family Peptidase_S8 PF00082.17 EEQ75939.1 - 7.2e-07 28.6 0.0 0.0053 15.9 0.0 2.5 2 0 0 2 2 2 2 Subtilase family RHIM PF12721.2 EEQ75939.1 - 3 8.3 4.7 3.1 8.2 1.5 2.3 2 0 0 2 2 2 0 RIP homotypic interaction motif DUF2252 PF10009.4 EEQ75941.1 - 7.9e-113 377.2 0.2 9.6e-113 376.9 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2252) APH PF01636.18 EEQ75941.1 - 1.1e-06 28.5 0.5 0.00012 21.8 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family DNA_alkylation PF08713.6 EEQ75942.1 - 0.033 13.6 0.2 0.64 9.4 0.2 2.2 2 0 0 2 2 2 0 DNA alkylation repair enzyme NCA2 PF08637.5 EEQ75943.1 - 1.1e-82 277.2 0.0 1.7e-82 276.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 TMEM171 PF15471.1 EEQ75943.1 - 0.17 10.6 0.1 0.53 9.0 0.0 1.7 2 0 0 2 2 2 0 Transmembrane protein family 171 FA_hydroxylase PF04116.8 EEQ75944.1 - 3.2e-16 59.7 17.7 3.2e-16 59.7 12.3 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Fcf1 PF04900.7 EEQ75945.1 - 3.6e-41 139.3 0.4 3.6e-41 139.3 0.3 1.7 2 0 0 2 2 2 1 Fcf1 XPG_I_2 PF12813.2 EEQ75946.1 - 2e-89 299.3 0.0 2.7e-89 298.9 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 EEQ75946.1 - 0.02 14.9 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 XPG I-region RCR PF12273.3 EEQ75947.1 - 0.023 15.2 0.2 0.083 13.4 0.0 2.0 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Utp21 PF04192.7 EEQ75948.1 - 5.4e-78 261.3 0.0 9.1e-78 260.6 0.0 1.4 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EEQ75948.1 - 6.6e-18 63.8 33.0 0.0004 20.1 0.1 10.0 11 0 0 11 11 11 6 WD domain, G-beta repeat DUF1643 PF07799.7 EEQ75948.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) Cytochrom_D1 PF02239.11 EEQ75948.1 - 0.086 11.1 0.0 0.21 9.8 0.0 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain His_Phos_2 PF00328.17 EEQ75949.1 - 2.8e-117 391.9 0.0 4e-117 391.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EEQ75949.1 - 2.3e-06 27.1 0.0 5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain DUF111 PF01969.12 EEQ75949.1 - 0.32 9.7 2.4 0.56 8.9 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF111 DAGK_cat PF00781.19 EEQ75950.1 - 3.2e-07 29.8 0.2 6.1e-07 28.9 0.2 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF676 PF05057.9 EEQ75951.1 - 4.1e-40 137.4 0.0 4.4e-27 94.8 0.0 3.3 3 0 0 3 3 3 3 Putative serine esterase (DUF676) DUF455 PF04305.9 EEQ75953.1 - 6e-105 350.0 0.1 6e-105 350.0 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF455) Rieske PF00355.21 EEQ75953.1 - 6.7e-07 28.7 0.1 1.4e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 EEQ75953.1 - 0.0056 16.3 0.0 0.071 12.8 0.0 2.4 1 1 0 2 2 2 1 Rieske-like [2Fe-2S] domain DUF1168 PF06658.7 EEQ75953.1 - 0.012 15.1 1.6 0.019 14.4 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) IBR PF01485.16 EEQ75954.1 - 1.2e-14 53.9 37.5 5.1e-09 35.8 3.5 3.7 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 EEQ75954.1 - 0.0067 16.2 7.7 0.0067 16.2 5.4 3.3 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEQ75954.1 - 0.018 15.0 7.6 0.018 15.0 5.3 3.8 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) BAF1_ABF1 PF04684.8 EEQ75954.1 - 1.5 7.5 12.3 0.87 8.3 3.7 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor SelP_N PF04592.9 EEQ75954.1 - 4.7 6.5 14.7 12 5.1 10.2 1.7 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Inositol_P PF00459.20 EEQ75955.1 - 1e-68 231.5 0.0 1.2e-68 231.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF383 PF04063.9 EEQ75956.1 - 2.2e-73 245.9 0.3 9.5e-73 243.8 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EEQ75956.1 - 3.2e-23 81.0 1.5 9.2e-23 79.5 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF384) Rep-A_N PF04057.7 EEQ75957.1 - 0.0002 21.0 0.0 0.00037 20.2 0.0 1.3 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain TFIIF_alpha PF05793.7 EEQ75958.1 - 2.8e-05 22.7 71.5 3.9e-05 22.2 42.5 3.9 1 1 1 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Acyl_transf_1 PF00698.16 EEQ75959.1 - 2.8e-84 283.1 0.0 4.4e-83 279.2 0.0 2.8 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EEQ75959.1 - 2.8e-39 133.2 0.6 1.8e-38 130.6 0.0 2.3 2 0 0 2 2 2 1 MaoC like domain DUF1729 PF08354.5 EEQ75959.1 - 1.2e-32 111.4 0.4 8.3e-32 108.7 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EEQ75959.1 - 9e-21 74.0 0.0 4.3e-20 71.8 0.0 2.2 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EEQ75959.1 - 0.00011 21.4 0.0 0.071 12.2 0.0 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase adh_short_C2 PF13561.1 EEQ75960.1 - 6.2e-23 81.8 0.0 6.7e-22 78.4 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 EEQ75960.1 - 1.7e-19 70.2 0.0 5.6e-19 68.6 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 EEQ75960.1 - 3.6e-18 65.4 0.0 7.5e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EEQ75960.1 - 6.2e-10 38.9 0.1 2.2e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EEQ75960.1 - 1.1e-05 25.3 0.0 2.7e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase TRM PF02005.11 EEQ75961.1 - 5.3e-109 364.5 0.0 1.5e-96 323.6 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 EEQ75961.1 - 0.00021 20.9 0.1 0.00056 19.5 0.0 1.7 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_3 PF01596.12 EEQ75961.1 - 0.0088 15.1 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 EEQ75961.1 - 0.014 15.0 0.0 0.032 13.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain DUF2067 PF09840.4 EEQ75961.1 - 0.014 14.9 0.0 0.041 13.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2067) Methyltransf_18 PF12847.2 EEQ75961.1 - 0.022 15.3 0.1 0.066 13.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EEQ75961.1 - 0.15 11.3 0.1 0.57 9.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Pex14_N PF04695.8 EEQ75961.1 - 6.1 6.8 10.1 7.7 6.5 0.3 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Iso_dh PF00180.15 EEQ75962.1 - 1.3e-96 323.6 0.0 6.7e-96 321.2 0.0 1.8 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1691 PF07950.6 EEQ75963.1 - 6.9e-46 154.7 7.5 1e-29 102.6 2.5 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) DUF1469 PF07332.6 EEQ75963.1 - 1.5 8.5 7.8 0.2 11.4 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) zf-C2H2 PF00096.21 EEQ75964.1 - 0.0065 16.7 1.2 0.012 15.9 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.2 EEQ75964.1 - 0.0074 16.4 0.3 0.012 15.8 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EEQ75964.1 - 0.013 15.8 0.4 0.026 14.8 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEQ75964.1 - 0.071 13.2 1.9 0.11 12.6 1.3 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EEQ75964.1 - 0.074 13.1 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EEQ75964.1 - 0.075 12.9 0.5 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger UPF0240 PF06784.6 EEQ75964.1 - 0.083 12.5 0.1 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) Glyco_hydro_43 PF04616.9 EEQ75965.1 - 2.6e-51 174.4 1.3 3.6e-51 173.9 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GrpE PF01025.14 EEQ75966.1 - 0.31 10.5 5.1 0.65 9.5 3.5 1.4 1 0 0 1 1 1 0 GrpE Piwi PF02171.12 EEQ75967.1 - 4.8e-12 45.4 0.0 1.5e-10 40.5 0.0 2.6 2 1 0 2 2 2 1 Piwi domain PAZ PF02170.17 EEQ75967.1 - 3.3e-11 42.6 0.0 6.4e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EEQ75967.1 - 3.2e-10 39.2 0.0 9.7e-10 37.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Transket_pyr PF02779.19 EEQ75968.1 - 2e-45 154.4 0.0 3.2e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EEQ75968.1 - 1.8e-34 118.3 0.0 4.6e-34 117.0 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Metallophos PF00149.23 EEQ75969.1 - 3.3e-08 33.1 4.1 5.6e-08 32.4 2.9 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Apc9 PF12856.2 EEQ75969.1 - 0.069 13.2 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 Herpes_LMP1 PF05297.6 EEQ75969.1 - 0.2 10.5 6.1 0.3 9.9 4.2 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) ADH_zinc_N PF00107.21 EEQ75970.1 - 7e-12 45.0 0.0 1.7e-11 43.7 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEQ75970.1 - 0.0048 16.6 0.0 0.0087 15.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 EEQ75970.1 - 0.006 16.5 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ75970.1 - 0.0092 15.6 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Ank_2 PF12796.2 EEQ75971.1 - 4.7e-20 71.7 0.0 6.1e-10 39.3 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEQ75971.1 - 6e-13 48.5 0.1 4e-08 33.2 0.0 3.5 2 1 1 3 3 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EEQ75971.1 - 4.2e-12 45.2 0.0 1.7e-06 27.5 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EEQ75971.1 - 5.7e-09 35.3 0.0 0.0061 16.6 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EEQ75971.1 - 1.1e-08 35.3 0.2 2e-06 28.1 0.0 3.6 3 1 1 4 4 3 2 Ankyrin repeats (many copies) NACHT PF05729.7 EEQ75971.1 - 1.6e-08 34.3 0.0 4e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EEQ75971.1 - 3.6e-05 23.8 0.6 0.00014 21.9 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEQ75971.1 - 0.00037 20.6 0.2 0.0041 17.2 0.0 2.8 2 1 1 3 3 3 1 AAA domain DUF2075 PF09848.4 EEQ75971.1 - 0.0011 18.0 0.0 0.0053 15.7 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 EEQ75971.1 - 0.0018 17.8 0.5 0.023 14.2 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EEQ75971.1 - 0.0043 16.5 0.0 0.033 13.6 0.0 2.3 3 0 0 3 3 3 1 AAA-like domain RNase_H2-Ydr279 PF09468.5 EEQ75971.1 - 0.0077 15.4 0.1 0.012 14.8 0.1 1.2 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) NB-ARC PF00931.17 EEQ75971.1 - 0.012 14.4 0.0 0.025 13.4 0.0 1.6 1 1 0 1 1 1 0 NB-ARC domain cobW PF02492.14 EEQ75971.1 - 0.014 14.7 0.0 0.2 11.0 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 EEQ75971.1 - 0.018 14.7 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase Viral_helicase1 PF01443.13 EEQ75971.1 - 0.019 14.5 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 EEQ75971.1 - 0.064 13.1 0.1 0.3 11.0 0.0 2.2 3 0 0 3 3 2 0 AAA domain DNA_pol3_beta PF00712.14 EEQ75971.1 - 0.11 12.3 0.3 0.24 11.2 0.2 1.5 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain TCP PF03634.8 EEQ75972.1 - 0.065 13.6 0.4 0.067 13.5 0.3 1.1 1 0 0 1 1 1 0 TCP family transcription factor APH PF01636.18 EEQ75973.1 - 0.015 15.0 0.0 0.19 11.4 0.0 2.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.27 EEQ75974.1 - 1.9e-11 43.3 21.6 0.00098 18.9 0.6 7.4 8 0 0 8 8 8 6 WD domain, G-beta repeat IF2_assoc PF08364.6 EEQ75974.1 - 0.084 12.9 0.3 0.41 10.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial translation initiation factor IF-2 associated region Ank_2 PF12796.2 EEQ75975.1 - 3.4e-30 104.2 0.0 1e-08 35.3 0.0 5.7 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEQ75975.1 - 2.5e-29 101.1 0.2 8.6e-09 35.6 0.0 7.8 5 3 3 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.25 EEQ75975.1 - 4.5e-25 86.1 0.1 0.0011 18.6 0.0 9.4 9 0 0 9 9 9 5 Ankyrin repeat Ank_3 PF13606.1 EEQ75975.1 - 3.1e-20 70.2 0.1 0.074 13.3 0.0 8.8 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.1 EEQ75975.1 - 1.3e-19 69.7 1.3 0.0016 18.5 0.0 7.3 5 4 2 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEQ75976.1 - 7.7e-30 103.0 0.0 1.6e-08 34.7 0.0 5.1 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ75976.1 - 2.5e-24 83.8 0.2 3.7e-05 23.3 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 EEQ75976.1 - 6.1e-21 74.3 0.1 0.0022 18.4 0.0 6.3 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ75976.1 - 2.4e-20 70.5 0.7 0.052 13.8 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 EEQ75976.1 - 1.1e-19 69.9 0.2 0.0018 18.4 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeats (many copies) F-box-like PF12937.2 EEQ75976.1 - 0.0032 17.1 0.2 0.006 16.2 0.2 1.4 1 0 0 1 1 1 1 F-box-like ATP-synt_ab PF00006.20 EEQ75977.1 - 1.1e-61 208.0 0.0 1.8e-61 207.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EEQ75977.1 - 2.1e-25 89.4 0.5 3.8e-25 88.5 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EEQ75977.1 - 3.5e-24 84.8 3.4 8.8e-24 83.5 1.7 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 EEQ75977.1 - 0.0054 16.1 0.1 0.039 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EEQ75977.1 - 0.0087 15.7 0.0 0.024 14.3 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 EEQ75977.1 - 0.016 15.2 0.2 0.32 10.9 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 EEQ75977.1 - 0.017 15.3 0.0 0.47 10.6 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EEQ75977.1 - 0.018 14.2 0.1 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 KaiC PF06745.8 EEQ75977.1 - 0.025 13.7 0.1 0.045 12.8 0.1 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 EEQ75977.1 - 0.026 14.1 0.1 0.072 12.7 0.0 1.8 2 0 0 2 2 2 0 NACHT domain MobB PF03205.9 EEQ75977.1 - 0.052 13.2 0.1 1.3 8.7 0.0 2.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EEQ75977.1 - 0.069 13.2 0.0 0.34 11.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EEQ75977.1 - 0.07 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 EEQ75977.1 - 0.14 10.9 0.7 0.62 8.8 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain Alpha-amylase_C PF02806.13 EEQ75978.1 - 1e-23 83.2 0.0 2.6e-23 81.9 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EEQ75978.1 - 2e-19 70.1 0.0 5.2e-14 52.3 0.0 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EEQ75978.1 - 2e-16 59.7 0.1 5.7e-16 58.3 0.1 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Zn_clus PF00172.13 EEQ75979.1 - 2.7e-05 23.9 2.0 5.6e-05 22.9 1.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 EEQ75980.1 - 1.5e-52 178.2 12.8 2.1e-52 177.8 8.9 1.1 1 0 0 1 1 1 1 RTA1 like protein Transgly_assoc PF04226.8 EEQ75980.1 - 0.0018 18.3 1.5 1.7 8.7 0.0 3.0 2 1 0 2 2 2 2 Transglycosylase associated protein DUF2759 PF10958.3 EEQ75980.1 - 0.039 13.5 6.1 0.75 9.4 1.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) DUF3112 PF11309.3 EEQ75980.1 - 0.98 9.1 13.3 0.071 12.9 3.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3112) Pyr_redox_3 PF13738.1 EEQ75981.1 - 1.2e-26 94.0 0.0 2.5e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EEQ75981.1 - 1.1e-13 50.3 0.0 1.6e-12 46.4 0.0 2.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EEQ75981.1 - 5.1e-11 42.4 0.0 7.1e-10 38.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EEQ75981.1 - 1.2e-08 34.3 0.2 3.1e-06 26.3 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EEQ75981.1 - 3.6e-07 29.4 1.3 1.1e-05 24.5 0.1 3.4 3 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 EEQ75981.1 - 1.2e-06 27.7 0.0 4.2e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EEQ75981.1 - 1.2e-05 25.2 0.0 0.00047 20.0 0.0 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEQ75981.1 - 0.0021 17.8 4.5 1.2 8.9 0.0 4.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EEQ75981.1 - 0.0069 15.3 0.0 0.029 13.2 0.0 2.0 3 0 0 3 3 3 1 Lycopene cyclase protein Amino_oxidase PF01593.19 EEQ75981.1 - 0.0082 15.2 0.0 0.034 13.2 0.0 1.8 1 1 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EEQ75981.1 - 0.0084 16.4 0.0 4.9 7.6 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEQ75981.1 - 0.012 14.5 0.2 0.07 11.9 0.0 2.2 3 0 0 3 3 3 0 FAD binding domain Shikimate_DH PF01488.15 EEQ75981.1 - 0.037 14.1 0.1 11 6.1 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EEQ75981.1 - 0.16 12.2 0.0 1.2 9.4 0.0 2.3 3 0 0 3 3 3 0 Putative NAD(P)-binding Abhydrolase_3 PF07859.8 EEQ75982.1 - 3.9e-23 82.1 0.0 5.1e-22 78.4 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EEQ75982.1 - 3.5e-14 52.2 0.0 5.2e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 EEQ75982.1 - 2.6e-06 27.4 0.5 8.1e-06 25.8 0.1 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ75982.1 - 0.00029 20.6 0.1 0.00052 19.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EEQ75982.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 EEQ75982.1 - 0.051 13.1 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Arginase PF00491.16 EEQ75982.1 - 0.057 12.7 0.0 0.12 11.6 0.0 1.5 2 0 0 2 2 2 0 Arginase family Peptidase_S9 PF00326.16 EEQ75982.1 - 0.12 11.5 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family adh_short PF00106.20 EEQ75983.1 - 5.9e-25 88.1 0.6 2.1e-24 86.2 0.3 2.0 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ75983.1 - 3.4e-08 33.5 0.0 4.7e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ75983.1 - 7.5e-08 32.2 2.0 1.8e-06 27.7 0.9 2.6 1 1 1 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EEQ75983.1 - 0.00012 22.1 0.0 0.00024 21.1 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding DUF2316 PF10078.4 EEQ75983.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) Epimerase PF01370.16 EEQ75983.1 - 0.028 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.17 EEQ75984.1 - 7.2e-73 245.6 0.0 9.9e-73 245.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 YhhN PF07947.9 EEQ75985.1 - 1.4e-39 135.4 0.1 2.2e-39 134.7 0.1 1.3 1 1 0 1 1 1 1 YhhN-like protein DUF1097 PF06496.6 EEQ75985.1 - 1.7 8.4 9.2 1.4 8.7 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1097) WW PF00397.21 EEQ75986.1 - 2.1e-09 37.0 2.2 5.3e-09 35.7 1.5 1.7 1 0 0 1 1 1 1 WW domain DUF2012 PF09430.5 EEQ75987.1 - 2.2e-26 92.1 0.0 2.8e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) AMP-binding PF00501.23 EEQ75989.1 - 1.2e-59 201.7 0.0 7.2e-45 153.1 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme HARP PF07443.8 EEQ75989.1 - 0.062 12.6 0.0 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 HepA-related protein (HARP) HlyIII PF03006.15 EEQ75990.1 - 4.8e-53 179.8 14.3 5.7e-53 179.5 9.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related Ank PF00023.25 EEQ75991.1 - 9e-32 107.3 0.7 9.4e-11 40.9 0.0 5.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 EEQ75991.1 - 1.5e-29 102.1 0.0 3.1e-13 49.8 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEQ75991.1 - 5.4e-23 80.9 1.3 2.4e-14 53.3 0.1 4.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ75991.1 - 9.9e-23 77.9 1.4 8e-07 28.7 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EEQ75991.1 - 3.9e-20 71.4 1.9 5e-09 36.1 0.0 4.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 EEQ75991.1 - 2.1e-14 53.0 0.4 5.7e-14 51.6 0.1 1.8 2 0 0 2 2 2 1 Phosphorylase superfamily NACHT PF05729.7 EEQ75991.1 - 1.6e-09 37.6 0.0 3.7e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 EEQ75991.1 - 0.13 11.2 0.1 0.36 9.7 0.0 1.7 2 0 0 2 2 2 0 KAP family P-loop domain DUF454 PF04304.8 EEQ75991.1 - 0.27 11.2 3.1 0.93 9.5 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF454) Thioredoxin PF00085.15 EEQ75992.1 - 8.5e-42 141.0 0.1 2e-22 78.8 0.0 4.2 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EEQ75992.1 - 1.2e-13 51.2 0.0 0.0023 17.7 0.0 4.2 2 1 2 4 4 4 4 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EEQ75992.1 - 3.4e-07 30.4 3.8 0.14 12.3 0.1 4.3 3 1 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EEQ75992.1 - 0.00025 21.1 0.3 0.43 10.7 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like HyaE PF07449.6 EEQ75992.1 - 0.0016 18.3 0.0 0.67 9.8 0.0 2.9 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 EEQ75992.1 - 0.028 14.4 0.2 0.15 12.1 0.1 2.2 2 0 0 2 2 2 0 Thioredoxin-like Calsequestrin PF01216.12 EEQ75992.1 - 0.08 11.7 0.9 0.15 10.8 0.1 1.7 2 0 0 2 2 2 0 Calsequestrin Thioredoxin_3 PF13192.1 EEQ75992.1 - 0.095 12.5 0.0 0.54 10.1 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain ETC_C1_NDUFA5 PF04716.9 EEQ75993.1 - 1.5e-23 82.0 0.5 1.5e-23 82.0 0.4 2.5 3 0 0 3 3 3 1 ETC complex I subunit conserved region YlqD PF11068.3 EEQ75993.1 - 0.15 12.0 6.1 0.085 12.8 2.6 1.7 2 0 0 2 2 2 0 YlqD protein Fes1 PF08609.5 EEQ75993.1 - 1.4 9.4 4.1 1.4 9.4 0.7 2.3 2 1 1 3 3 3 0 Nucleotide exchange factor Fes1 Coatomer_WDAD PF04053.9 EEQ75994.1 - 1.8e-167 557.6 0.0 3.8e-167 556.5 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EEQ75994.1 - 1.4e-45 151.6 4.3 2.5e-10 39.8 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EEQ75994.1 - 0.00013 20.2 0.3 0.037 12.1 0.0 3.6 3 1 0 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EEQ75994.1 - 0.0022 17.7 0.0 2.8 7.7 0.0 3.4 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Pkinase PF00069.20 EEQ75995.1 - 1.9e-70 236.9 0.0 2.7e-70 236.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ75995.1 - 6e-33 114.0 0.0 8.4e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EEQ75995.1 - 4.9e-09 36.5 0.1 1.6e-08 34.9 0.1 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EEQ75995.1 - 0.00011 21.2 0.0 0.00016 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SWIRM PF04433.12 EEQ75996.1 - 2e-17 63.0 0.0 6.7e-17 61.3 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 EEQ75996.1 - 5.5e-10 38.6 6.7 9.8e-10 37.8 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EEQ75996.1 - 3.2e-08 33.4 0.0 9e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain MDH PF02315.11 EEQ75996.1 - 0.12 12.3 2.0 1.8 8.5 0.1 2.6 2 0 0 2 2 2 0 Methanol dehydrogenase beta subunit ECH PF00378.15 EEQ75997.1 - 1.4e-34 119.3 1.9 8.9e-32 110.1 1.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family DUF1838 PF08894.6 EEQ75997.1 - 0.097 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1838) Pkinase PF00069.20 EEQ75999.1 - 1.8e-26 92.8 0.0 5.2e-26 91.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ75999.1 - 5.2e-11 42.1 0.0 7.8e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EEQ75999.1 - 0.0043 17.1 0.0 0.0086 16.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain YrbL-PhoP_reg PF10707.4 EEQ75999.1 - 0.14 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Mito_fiss_reg PF05308.6 EEQ76000.1 - 0.042 13.2 5.3 0.063 12.6 3.7 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CDC27 PF09507.5 EEQ76000.1 - 0.4 9.8 4.4 0.45 9.6 3.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Mucin PF01456.12 EEQ76000.1 - 4.4 7.0 39.8 0.36 10.5 24.2 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein Dicty_REP PF05086.7 EEQ76000.1 - 8.9 3.9 6.9 11 3.6 4.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mannitol_dh_C PF08125.8 EEQ76002.1 - 8.2e-51 172.5 0.1 1.2e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EEQ76002.1 - 2.5e-20 72.9 0.2 1e-19 70.9 0.0 2.0 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.9 EEQ76002.1 - 0.00019 20.8 0.8 0.0014 18.0 0.1 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EEQ76002.1 - 0.0002 21.0 0.9 0.0017 18.0 0.0 2.6 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Latarcin PF10279.4 EEQ76002.1 - 0.048 13.8 0.2 0.54 10.4 0.0 2.3 2 0 0 2 2 2 0 Latarcin precursor PPR_2 PF13041.1 EEQ76003.1 - 1.1e-22 79.6 0.0 3.9e-16 58.7 0.0 3.7 2 1 1 3 3 3 2 PPR repeat family PPR PF01535.15 EEQ76003.1 - 2.7e-06 26.9 0.5 0.048 13.6 0.0 4.9 5 0 0 5 5 5 1 PPR repeat PPR_3 PF13812.1 EEQ76003.1 - 6.4e-05 22.9 0.1 5.1 7.6 0.0 5.2 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR_1 PF12854.2 EEQ76003.1 - 0.014 14.8 0.5 3.8 7.0 0.0 3.6 4 0 0 4 4 4 0 PPR repeat RCC1 PF00415.13 EEQ76004.1 - 2.7e-36 123.5 10.2 1.2e-08 35.0 0.0 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EEQ76004.1 - 2.5e-21 74.7 25.9 9.7e-07 28.2 0.2 7.2 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Rad9 PF04139.8 EEQ76005.1 - 2.9e-55 187.1 2.9 3.9e-55 186.7 2.0 1.2 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 EEQ76005.1 - 8.3e-05 21.4 0.3 0.00012 20.9 0.2 1.3 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 CorA PF01544.13 EEQ76005.1 - 0.059 12.3 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein MSSP PF03940.8 EEQ76008.1 - 8.1 5.9 15.0 0.14 11.5 2.4 2.4 2 0 0 2 2 2 0 Male specific sperm protein DEAD PF00270.24 EEQ76010.1 - 1.7e-45 154.5 0.0 1.1e-43 148.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ76010.1 - 5.4e-28 96.6 0.0 1.2e-27 95.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ76010.1 - 0.00015 21.6 0.0 0.00047 20.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EEQ76010.1 - 0.0074 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1253 PF06862.7 EEQ76010.1 - 0.034 12.5 0.0 1.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) DUF2443 PF10398.4 EEQ76010.1 - 0.079 12.7 0.3 0.17 11.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Phos_pyr_kin PF08543.7 EEQ76011.1 - 4.2e-85 284.8 1.4 5.4e-85 284.5 0.9 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EEQ76011.1 - 7.2e-60 202.3 0.1 1e-59 201.8 0.1 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 EEQ76011.1 - 5.9e-08 32.1 0.4 1e-07 31.4 0.3 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 EEQ76011.1 - 7.3e-05 22.0 0.4 0.0041 16.3 0.0 2.3 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family Carb_kinase PF01256.12 EEQ76011.1 - 0.00049 19.4 3.4 0.0084 15.4 2.4 2.2 1 1 0 1 1 1 1 Carbohydrate kinase Herpes_ori_bp PF02399.10 EEQ76011.1 - 0.14 10.1 0.0 0.18 9.7 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein DNA_pol_B PF00136.16 EEQ76012.1 - 2.2e-113 379.4 5.0 4e-113 378.6 3.4 1.4 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EEQ76012.1 - 9.2e-68 227.3 0.8 9.2e-68 227.3 0.5 1.8 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EEQ76012.1 - 1.9e-37 128.8 0.0 5.4e-37 127.3 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EEQ76012.1 - 6.7e-25 86.7 9.0 6.7e-25 86.7 6.2 2.8 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal Ribosomal_L30_N PF08079.7 EEQ76013.1 - 5.9e-26 90.2 14.4 1.1e-25 89.4 10.0 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EEQ76013.1 - 1.2e-17 63.2 3.5 1.6e-17 62.7 1.5 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e EAP30 PF04157.11 EEQ76015.1 - 3.3e-58 196.4 0.0 7.3e-58 195.3 0.0 1.5 1 1 0 1 1 1 1 EAP30/Vps36 family MarR_2 PF12802.2 EEQ76015.1 - 0.089 12.4 0.2 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 MarR family eIF-3c_N PF05470.7 EEQ76016.1 - 3.3e-175 583.5 31.3 1e-140 469.6 3.1 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EEQ76016.1 - 9.1e-12 45.2 9.2 1.2e-11 44.8 0.0 4.3 4 0 0 4 4 4 1 PCI domain Pkinase PF00069.20 EEQ76017.1 - 2.2e-52 177.7 0.0 5.2e-52 176.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ76017.1 - 7.5e-24 84.1 0.1 1.7e-23 83.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EEQ76017.1 - 0.00025 20.8 4.5 0.00072 19.3 0.0 2.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 EEQ76017.1 - 0.0029 16.9 0.2 0.0089 15.3 0.2 1.7 1 1 0 1 1 1 1 RIO1 family DUF4430 PF14478.1 EEQ76017.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) Pkinase PF00069.20 EEQ76019.1 - 1.2e-60 204.8 0.0 4e-60 203.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ76019.1 - 4.4e-26 91.5 0.0 6.5e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EEQ76019.1 - 0.0033 16.7 0.1 0.0033 16.7 0.1 1.6 2 1 0 2 2 2 1 RIO1 family Kinase-like PF14531.1 EEQ76019.1 - 0.0051 15.7 0.0 0.011 14.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEQ76019.1 - 0.54 9.9 3.4 0.29 10.8 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Usp PF00582.21 EEQ76022.1 - 7.5e-20 71.5 0.1 1.4e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Universal stress protein family Med27 PF11571.3 EEQ76024.1 - 1e-17 64.0 0.4 2.4e-17 62.8 0.2 1.6 2 0 0 2 2 2 1 Mediator complex subunit 27 Transposase_mut PF00872.13 EEQ76024.1 - 0.051 12.1 0.0 0.15 10.5 0.0 1.8 1 1 1 2 2 2 0 Transposase, Mutator family SNF2_N PF00176.18 EEQ76026.1 - 6.1e-70 235.3 0.0 9.1e-70 234.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ76026.1 - 7.3e-14 51.3 0.0 1.7e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1096 PF06493.6 EEQ76028.1 - 1.7 8.6 32.1 6.5e+02 0.3 22.3 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1096) Metallothio_Euk PF12749.2 EEQ76028.1 - 8.8 6.4 27.2 13 5.9 18.9 1.2 1 0 0 1 1 1 0 Eukaryotic metallothionein Homeobox PF00046.24 EEQ76029.1 - 7.5e-17 60.7 3.2 1.4e-16 59.8 2.2 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EEQ76029.1 - 0.019 14.6 0.1 0.056 13.1 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain efThoc1 PF11957.3 EEQ76031.1 - 1.9e-154 514.8 7.5 4e-154 513.7 5.2 1.5 1 1 0 1 1 1 1 THO complex subunit 1 transcription elongation factor AAA_12 PF13087.1 EEQ76032.1 - 2.5e-26 92.3 0.0 4.5e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEQ76032.1 - 4.4e-23 82.1 0.0 7.4e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ76032.1 - 4.1e-09 36.0 0.1 2.6e-08 33.4 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EEQ76032.1 - 1.1e-05 25.0 0.0 0.004 16.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EEQ76032.1 - 8.3e-05 22.4 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EEQ76032.1 - 0.00027 20.3 0.0 0.00063 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EEQ76032.1 - 0.0014 18.2 0.1 0.05 13.1 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 EEQ76032.1 - 0.0015 18.0 0.0 0.028 13.9 0.0 2.6 3 0 0 3 3 2 1 DEAD/DEAH box helicase AAA_17 PF13207.1 EEQ76032.1 - 0.0029 18.3 0.1 0.43 11.3 0.0 3.4 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 EEQ76032.1 - 0.0034 17.5 0.0 0.01 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EEQ76032.1 - 0.0039 17.3 0.0 0.015 15.5 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EEQ76032.1 - 0.014 14.3 0.8 0.022 13.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 EEQ76032.1 - 0.03 14.0 0.0 0.077 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EEQ76032.1 - 0.032 14.2 0.0 0.099 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 EEQ76032.1 - 0.033 13.2 0.0 0.089 11.8 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin UvrD-helicase PF00580.16 EEQ76032.1 - 0.036 13.3 0.0 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DnaB_C PF03796.10 EEQ76032.1 - 0.069 12.0 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain UvrD_C_2 PF13538.1 EEQ76032.1 - 0.082 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_14 PF13173.1 EEQ76032.1 - 0.084 12.7 0.1 0.51 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EEQ76032.1 - 0.084 11.7 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EEQ76032.1 - 0.11 12.6 0.1 0.9 9.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase KaiC PF06745.8 EEQ76032.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 KaiC PIF1 PF05970.9 EEQ76032.1 - 0.15 11.0 0.0 8 5.3 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase Parvo_NS1 PF01057.12 EEQ76032.1 - 0.17 10.7 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATP-synt_ab PF00006.20 EEQ76032.1 - 0.19 11.1 0.0 0.44 10.0 0.0 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain 4HBT PF03061.17 EEQ76033.1 - 1.6e-14 53.7 0.0 2.3e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Tfb2 PF03849.9 EEQ76034.1 - 3e-145 483.4 0.0 5.6e-145 482.5 0.0 1.4 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EEQ76034.1 - 3.1e-06 26.9 0.0 8.6e-05 22.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SinI PF08671.5 EEQ76034.1 - 0.1 12.0 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 Anti-repressor SinI PhzC-PhzF PF02567.11 EEQ76036.1 - 6.7e-43 146.9 0.8 3.8e-42 144.4 0.5 1.9 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein TIMELESS PF04821.9 EEQ76037.1 - 5.3e-64 216.0 0.4 2.9e-50 170.9 0.0 2.8 1 1 1 2 2 2 2 Timeless protein TIMELESS_C PF05029.8 EEQ76037.1 - 2.5e-45 155.5 25.8 2.8e-45 155.3 9.0 4.1 2 1 1 3 3 3 1 Timeless protein C terminal region Vitellogenin_N PF01347.17 EEQ76037.1 - 0.018 13.3 0.5 0.032 12.5 0.3 1.3 1 0 0 1 1 1 0 Lipoprotein amino terminal region 3HCDH_N PF02737.13 EEQ76038.1 - 3.5e-54 183.1 1.7 4.9e-54 182.7 1.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EEQ76038.1 - 2.1e-34 117.7 0.0 5.9e-34 116.3 0.0 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ApbA PF02558.11 EEQ76038.1 - 6.4e-07 28.9 0.1 0.00019 20.8 0.0 2.2 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 EEQ76038.1 - 2.7e-06 27.3 0.5 6.3e-06 26.1 0.4 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EEQ76038.1 - 6.3e-05 22.7 0.3 9.7e-05 22.1 0.2 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 EEQ76038.1 - 0.00027 20.0 0.1 0.00032 19.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Pyr_redox PF00070.22 EEQ76038.1 - 0.00046 20.5 0.2 0.0011 19.3 0.0 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEQ76038.1 - 0.0013 17.7 0.0 0.002 17.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 EEQ76038.1 - 0.002 17.5 0.0 0.0039 16.5 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.9 EEQ76038.1 - 0.0044 16.9 0.0 0.0056 16.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EEQ76038.1 - 0.0051 15.9 0.4 0.011 14.8 0.1 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RsbU_N PF08673.5 EEQ76038.1 - 0.015 15.3 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain Pyr_redox_3 PF13738.1 EEQ76038.1 - 0.027 14.5 0.9 0.34 10.9 0.5 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EEQ76038.1 - 0.029 13.9 0.1 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EEQ76038.1 - 0.031 14.5 0.1 0.056 13.7 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding F420_oxidored PF03807.12 EEQ76038.1 - 0.067 13.6 0.6 0.067 13.6 0.4 2.3 2 1 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EEQ76038.1 - 0.073 13.0 1.0 0.11 12.4 0.1 1.8 2 0 0 2 2 1 0 TrkA-N domain HI0933_like PF03486.9 EEQ76038.1 - 0.13 10.7 0.8 0.21 10.0 0.6 1.3 1 0 0 1 1 1 0 HI0933-like protein TPR_12 PF13424.1 EEQ76041.1 - 5.4e-11 42.2 10.0 0.00049 19.9 0.3 3.6 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ76041.1 - 8.8e-07 28.3 6.2 0.47 10.4 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ76041.1 - 7.5e-06 26.4 6.9 0.0005 20.6 0.0 5.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ76041.1 - 2.7e-05 23.5 1.1 0.5 10.0 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ76041.1 - 0.00014 21.4 11.1 0.011 15.3 0.0 4.9 3 2 2 5 5 5 1 TPR repeat TPR_8 PF13181.1 EEQ76041.1 - 0.00016 21.2 1.2 0.2 11.4 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat Ank_4 PF13637.1 EEQ76041.1 - 0.00068 20.0 0.0 0.0021 18.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEQ76041.1 - 0.0012 19.1 0.0 0.0032 17.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TPR_7 PF13176.1 EEQ76041.1 - 0.0028 17.3 0.2 0.44 10.4 0.0 3.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ76041.1 - 0.0053 17.2 7.6 5.7 7.8 0.0 5.8 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ76041.1 - 0.0054 17.0 2.1 0.3 11.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat HET PF06985.6 EEQ76041.1 - 0.023 14.8 0.0 0.094 12.8 0.0 2.0 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) TPR_10 PF13374.1 EEQ76041.1 - 0.038 13.9 9.3 0.31 11.0 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ76041.1 - 0.05 14.0 6.0 15 6.3 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Actin PF00022.14 EEQ76042.1 - 1.4e-105 352.9 0.0 1.8e-105 352.6 0.0 1.0 1 0 0 1 1 1 1 Actin GCIP PF13324.1 EEQ76045.1 - 6.7e-05 22.2 2.5 0.00043 19.5 1.2 2.5 1 1 1 2 2 2 1 Grap2 and cyclin-D-interacting CDC45 PF02724.9 EEQ76045.1 - 0.0035 15.4 0.5 0.0043 15.1 0.4 1.1 1 0 0 1 1 1 1 CDC45-like protein Lin-8 PF03353.10 EEQ76045.1 - 0.051 12.8 1.4 0.081 12.2 0.9 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Prok-TraM PF09228.5 EEQ76045.1 - 0.057 13.5 0.5 0.23 11.5 0.3 2.2 2 1 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM Nop14 PF04147.7 EEQ76045.1 - 0.085 10.7 4.6 0.14 10.0 3.2 1.3 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 EEQ76045.1 - 0.34 10.5 11.5 1.6 8.2 8.0 2.0 1 1 0 1 1 1 0 Sigma-70, non-essential region Vfa1 PF08432.5 EEQ76045.1 - 0.44 10.5 4.0 0.71 9.8 2.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 LRR_4 PF12799.2 EEQ76046.1 - 2.5e-45 151.4 54.4 1.6e-10 40.3 1.7 10.8 9 1 3 12 12 12 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEQ76046.1 - 2.3e-29 100.9 54.3 5.1e-09 35.7 3.5 8.7 5 2 4 9 9 9 9 Leucine rich repeat LRR_7 PF13504.1 EEQ76046.1 - 1.9e-23 78.3 45.4 0.062 13.5 0.1 14.8 15 0 0 15 15 15 10 Leucine rich repeat LRR_1 PF00560.28 EEQ76046.1 - 2.1e-20 69.6 51.2 0.054 13.5 0.1 15.8 15 2 1 16 16 16 7 Leucine Rich Repeat LRR_6 PF13516.1 EEQ76046.1 - 3.2e-10 38.9 41.4 1.5 9.1 0.0 13.8 15 2 1 16 16 16 6 Leucine Rich repeat Ribosomal_L13e PF01294.13 EEQ76048.1 - 1.5e-67 226.5 3.1 2.1e-67 226.0 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Zein-binding PF04576.10 EEQ76049.1 - 0.06 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Zein-binding Oxidored-like PF09791.4 EEQ76050.1 - 3.1e-25 87.3 4.9 3.1e-25 87.3 3.4 1.8 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal KAP PF05804.7 EEQ76051.1 - 3.2e-06 25.3 0.0 0.00011 20.2 0.0 2.1 2 0 0 2 2 2 2 Kinesin-associated protein (KAP) DPM3 PF08285.6 EEQ76054.1 - 1.2e-18 66.7 0.2 5.1e-18 64.7 0.1 1.8 1 1 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Prefoldin PF02996.12 EEQ76054.1 - 0.012 15.2 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 Prefoldin subunit COX16 PF14138.1 EEQ76054.1 - 0.03 14.4 0.0 0.034 14.3 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Pribosyltran PF00156.22 EEQ76055.1 - 1.6e-09 37.5 0.1 1.3e-08 34.6 0.1 2.1 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Fungal_trans PF04082.13 EEQ76056.1 - 1.8e-21 76.2 1.3 2.6e-21 75.6 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.19 EEQ76057.1 - 8.8e-85 283.1 59.7 1.4e-45 155.0 12.2 2.5 3 0 0 3 3 2 2 ABC-2 type transporter PDR_CDR PF06422.7 EEQ76057.1 - 4.8e-36 122.5 5.7 1.9e-31 107.7 0.0 3.2 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 EEQ76057.1 - 8.9e-33 113.4 0.0 2.6e-16 60.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 EEQ76057.1 - 4.8e-17 61.8 0.0 1.2e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EEQ76057.1 - 1.5e-10 40.6 45.6 1.2e-07 31.1 13.5 3.2 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 EEQ76057.1 - 2.7e-08 33.4 0.8 0.00029 20.2 0.3 2.7 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EEQ76057.1 - 4.9e-06 26.4 0.1 0.066 13.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EEQ76057.1 - 1.3e-05 25.2 0.7 0.0031 17.5 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EEQ76057.1 - 4.7e-05 22.8 0.4 0.015 14.8 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EEQ76057.1 - 0.00037 19.6 0.0 0.008 15.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 EEQ76057.1 - 0.00046 19.6 1.0 0.091 12.1 0.4 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EEQ76057.1 - 0.00047 20.4 0.0 0.081 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EEQ76057.1 - 0.0011 19.8 0.0 0.52 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EEQ76057.1 - 0.0011 18.6 0.2 1.2 8.7 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.1 EEQ76057.1 - 0.0012 18.9 0.1 1.1 9.3 0.0 3.2 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.1 EEQ76057.1 - 0.011 15.4 1.4 4 7.2 0.1 2.9 2 0 0 2 2 2 0 Part of AAA domain SMC_N PF02463.14 EEQ76057.1 - 0.012 14.8 0.0 0.23 10.6 0.0 2.6 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA PF00004.24 EEQ76057.1 - 0.018 15.2 0.0 11 6.2 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 EEQ76057.1 - 0.065 13.1 0.0 1.8 8.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain PDR_assoc PF08370.6 EEQ76057.1 - 0.098 12.1 0.1 0.098 12.1 0.0 3.7 4 0 0 4 4 3 0 Plant PDR ABC transporter associated RuvB_N PF05496.7 EEQ76057.1 - 0.11 11.4 0.4 5.1 6.0 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_10 PF12846.2 EEQ76057.1 - 0.12 11.7 0.8 6.7 6.0 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain MMR_HSR1 PF01926.18 EEQ76057.1 - 0.37 10.7 0.5 8 6.4 0.2 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.1 EEQ76057.1 - 0.44 10.4 6.2 2.3 8.1 0.5 3.1 3 0 0 3 3 3 0 AAA domain HSF_DNA-bind PF00447.12 EEQ76059.1 - 3.4e-21 75.3 0.9 7.6e-21 74.2 0.6 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding DUF3245 PF11595.3 EEQ76060.1 - 9.7e-47 158.9 3.3 9.7e-47 158.9 2.3 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3245) ATP-grasp_2 PF08442.5 EEQ76061.1 - 5.4e-79 264.2 1.4 5.4e-79 264.2 1.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 EEQ76061.1 - 4.7e-25 87.9 0.2 1.2e-24 86.6 0.2 1.7 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EEQ76061.1 - 1.4e-08 34.2 2.0 1.8e-08 33.8 0.6 1.8 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 EEQ76061.1 - 0.0056 16.2 1.6 0.037 13.5 0.1 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 EEQ76061.1 - 0.0092 15.7 0.0 0.022 14.4 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain Succ_CoA_lig PF13607.1 EEQ76061.1 - 0.053 13.1 0.1 10 5.7 0.0 2.5 1 1 1 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain adh_short PF00106.20 EEQ76062.1 - 3.7e-22 79.0 0.0 7.1e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ76062.1 - 4.6e-15 56.0 0.1 5.3e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EEQ76062.1 - 7.1e-05 22.0 0.0 0.00047 19.3 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 EEQ76062.1 - 0.011 14.9 0.0 0.022 14.0 0.0 1.4 1 1 0 1 1 1 0 NmrA-like family ADH_zinc_N PF00107.21 EEQ76062.1 - 0.012 15.1 0.0 0.67 9.5 0.0 2.2 1 1 1 2 2 2 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EEQ76062.1 - 0.053 13.5 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 NADH(P)-binding MGS PF02142.17 EEQ76062.1 - 0.081 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 MGS-like domain Adaptin_N PF01602.15 EEQ76063.1 - 2.4e-126 422.1 4.1 2.9e-126 421.8 2.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EEQ76063.1 - 3.6e-44 149.3 0.0 7.5e-44 148.2 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EEQ76063.1 - 2.7e-19 69.5 0.0 6.5e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Ala_racemase_N PF01168.15 EEQ76064.1 - 5.3e-41 140.5 0.1 6.3e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain CENP-F_N PF10481.4 EEQ76068.1 - 0.11 11.8 0.2 0.12 11.6 0.2 1.0 1 0 0 1 1 1 0 Cenp-F N-terminal domain LSM PF01423.17 EEQ76069.1 - 2.8e-05 23.5 0.0 3.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEQ76069.1 - 0.0009 19.1 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Ribosomal_S17 PF00366.15 EEQ76071.1 - 5.2e-30 103.2 1.2 7.8e-30 102.7 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Spc7_N PF15402.1 EEQ76072.1 - 0 1261.0 46.5 0 1260.3 32.2 1.3 1 0 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 EEQ76072.1 - 1.3e-121 405.2 2.9 2.6e-121 404.2 2.0 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein MFS_1 PF07690.11 EEQ76073.1 - 1.4e-30 106.2 11.3 1.4e-30 106.2 7.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Pil1 PF13805.1 EEQ76075.1 - 4.7e-158 524.4 0.3 5.7e-158 524.1 0.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 EEQ76075.1 - 0.022 14.1 1.6 0.034 13.4 0.7 1.5 1 1 0 1 1 1 0 FAM92 protein RES PF08808.6 EEQ76076.1 - 0.03 14.4 0.0 0.033 14.3 0.0 1.2 1 0 0 1 1 1 0 RES domain SUR7 PF06687.7 EEQ76079.1 - 7.3e-49 166.1 5.6 9e-49 165.9 3.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF1345 PF07077.6 EEQ76080.1 - 0.11 11.9 0.8 0.12 11.8 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) RNase_HII PF01351.13 EEQ76080.1 - 0.44 10.1 2.3 0.59 9.7 1.4 1.5 1 1 1 2 2 2 0 Ribonuclease HII Homeobox PF00046.24 EEQ76083.1 - 4.2e-16 58.2 3.2 1.3e-15 56.6 2.2 1.9 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EEQ76083.1 - 1.4e-05 24.6 0.5 1.4e-05 24.6 0.4 2.5 2 0 0 2 2 2 1 Homeobox KN domain DUF4638 PF15472.1 EEQ76083.1 - 0.03 13.8 3.6 0.055 13.0 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF1045 PF06299.7 EEQ76083.1 - 0.034 13.8 1.9 0.095 12.3 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) Homez PF11569.3 EEQ76083.1 - 0.054 12.5 1.2 2.2 7.4 0.1 2.5 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez CRC_subunit PF08624.5 EEQ76084.1 - 1.4e-55 187.0 0.1 2.1e-55 186.4 0.1 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Macoilin PF09726.4 EEQ76084.1 - 1.7 6.8 7.5 3.2 5.9 5.2 1.4 1 0 0 1 1 1 0 Transmembrane protein Sdh_cyt PF01127.17 EEQ76087.1 - 7e-19 67.8 2.6 9.3e-19 67.4 1.8 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit SLD3 PF08639.5 EEQ76088.1 - 7.2e-151 503.2 10.1 1.3e-150 502.3 7.0 1.4 1 0 0 1 1 1 1 DNA replication regulator SLD3 S-AdoMet_synt_C PF02773.11 EEQ76089.1 - 3.9e-78 259.8 0.2 8.4e-78 258.7 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EEQ76089.1 - 3.4e-46 156.0 0.0 6.3e-46 155.2 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EEQ76089.1 - 7.5e-43 144.8 0.7 1.8e-42 143.6 0.1 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain ATP_bind_1 PF03029.12 EEQ76090.1 - 1.8e-76 256.8 0.0 2.3e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EEQ76090.1 - 4.7e-06 27.4 0.0 1.4e-05 25.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEQ76090.1 - 0.00031 20.6 0.0 0.00052 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEQ76090.1 - 0.00046 20.3 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ76090.1 - 0.00062 19.4 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EEQ76090.1 - 0.0016 18.4 0.0 0.0055 16.6 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EEQ76090.1 - 0.0017 18.2 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EEQ76090.1 - 0.0017 18.5 0.0 0.0032 17.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EEQ76090.1 - 0.0024 17.5 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EEQ76090.1 - 0.003 16.4 0.0 0.0053 15.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_31 PF13614.1 EEQ76090.1 - 0.0038 17.1 0.0 0.0088 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EEQ76090.1 - 0.0063 16.6 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase SRP54 PF00448.17 EEQ76090.1 - 0.0082 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain UPF0079 PF02367.12 EEQ76090.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 EEQ76090.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 EEQ76090.1 - 0.017 14.7 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EEQ76090.1 - 0.022 14.4 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 EEQ76090.1 - 0.034 13.5 0.0 0.09 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EEQ76090.1 - 0.036 13.5 0.0 0.11 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 EEQ76090.1 - 0.038 14.2 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EEQ76090.1 - 0.039 13.4 0.1 0.1 12.1 0.0 1.7 2 0 0 2 2 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EEQ76090.1 - 0.04 14.2 0.0 0.083 13.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.13 EEQ76090.1 - 0.058 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family cobW PF02492.14 EEQ76090.1 - 0.064 12.7 0.1 0.36 10.2 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KaiC PF06745.8 EEQ76090.1 - 0.068 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.1 EEQ76090.1 - 0.082 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EEQ76090.1 - 0.091 12.2 0.1 0.22 11.0 0.0 1.6 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 EEQ76090.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Septin Sigma54_activat PF00158.21 EEQ76090.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain GTP_EFTU PF00009.22 EEQ76090.1 - 0.13 11.6 0.0 4.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_5 PF07728.9 EEQ76090.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CbiA PF01656.18 EEQ76090.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.7 EEQ76090.1 - 0.17 10.9 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Apq12 PF12716.2 EEQ76091.1 - 3.7e-21 74.5 10.3 5.6e-21 73.9 7.1 1.3 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis NAD_binding_6 PF08030.7 EEQ76092.1 - 1.5e-13 50.9 0.0 3.1e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EEQ76092.1 - 7.7e-10 38.5 0.0 0.00073 19.3 0.0 2.5 1 1 1 2 2 2 2 FAD-binding domain Ferric_reduct PF01794.14 EEQ76092.1 - 1e-09 38.5 3.0 1.9e-09 37.7 2.1 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EEQ76092.1 - 0.015 15.8 0.0 10 6.7 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain HsbA PF12296.3 EEQ76093.1 - 0.022 14.6 3.7 4.2 7.2 0.5 2.9 2 0 0 2 2 2 0 Hydrophobic surface binding protein A DUF3867 PF12983.2 EEQ76093.1 - 0.78 9.6 5.2 0.59 10.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3867) 4HBT_2 PF13279.1 EEQ76094.1 - 1.2e-08 35.3 0.0 2.2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily HIG_1_N PF04588.8 EEQ76095.1 - 1.3e-06 28.0 2.1 1.3e-06 28.0 1.5 2.1 2 1 1 3 3 3 1 Hypoxia induced protein conserved region Med26 PF08711.6 EEQ76096.1 - 3e-12 45.8 0.0 7.1e-12 44.6 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Nup54 PF13874.1 EEQ76097.1 - 1.2e-46 157.9 1.2 1.2e-46 157.9 0.9 2.3 1 1 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 EEQ76097.1 - 2.7e-17 63.0 87.5 1.2e-10 41.5 37.0 3.3 1 1 2 3 3 3 2 Nucleoporin FG repeat region Fib_alpha PF08702.5 EEQ76097.1 - 0.32 11.1 6.2 0.091 12.8 1.8 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family AAA PF00004.24 EEQ76098.1 - 7.5e-15 55.3 0.0 2.3e-14 53.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEQ76098.1 - 2.3e-10 40.7 0.0 1.3e-09 38.2 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEQ76098.1 - 1.4e-08 34.9 0.0 4.3e-08 33.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EEQ76098.1 - 5.7e-05 22.7 1.1 0.00022 20.9 0.1 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 EEQ76098.1 - 0.00037 21.2 0.0 0.0037 18.0 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_11 PF13086.1 EEQ76098.1 - 0.0006 19.4 0.0 0.0012 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain BAH PF01426.13 EEQ76098.1 - 0.0026 17.4 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 BAH domain NACHT PF05729.7 EEQ76098.1 - 0.0026 17.4 0.0 0.0072 15.9 0.0 1.7 1 1 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 EEQ76098.1 - 0.0094 15.6 0.0 0.09 12.4 0.0 2.3 1 1 0 1 1 1 1 Archaeal ATPase AAA_33 PF13671.1 EEQ76098.1 - 0.011 15.6 0.0 0.088 12.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EEQ76098.1 - 0.013 15.4 0.0 0.042 13.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 EEQ76098.1 - 0.023 14.8 0.0 0.11 12.7 0.0 2.1 3 0 0 3 3 1 0 RNA helicase DUF3636 PF12331.3 EEQ76098.1 - 0.031 13.8 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3636) AAA_32 PF13654.1 EEQ76098.1 - 0.039 12.6 0.0 0.062 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EEQ76098.1 - 0.06 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.1 EEQ76098.1 - 0.067 13.4 0.0 0.22 11.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.9 EEQ76098.1 - 0.069 12.8 0.0 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 EEQ76098.1 - 0.12 11.2 0.0 0.24 10.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) WD40 PF00400.27 EEQ76099.1 - 8.8e-54 177.5 9.7 2.9e-10 39.6 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EEQ76099.1 - 0.00084 17.5 5.1 1.9 6.4 0.1 4.5 1 1 3 4 4 4 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EEQ76099.1 - 0.016 14.6 0.3 5.6 6.3 0.0 2.6 2 1 0 2 2 2 0 PQQ-like domain Nucleoporin_N PF08801.6 EEQ76099.1 - 0.037 12.7 0.0 1.3 7.6 0.0 2.4 1 1 0 2 2 2 0 Nup133 N terminal like Ank_2 PF12796.2 EEQ76100.1 - 3.3e-34 117.1 0.2 1.4e-13 51.0 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ76100.1 - 4.7e-31 105.0 1.0 3.5e-06 26.5 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EEQ76100.1 - 2.2e-30 103.9 1.6 3.4e-09 36.6 0.0 3.8 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEQ76100.1 - 2.1e-26 91.8 4.1 6.8e-08 32.8 0.0 4.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ76100.1 - 2.1e-22 76.9 0.4 0.00053 19.9 0.0 5.2 5 0 0 5 5 5 5 Ankyrin repeat Shal-type PF11601.3 EEQ76100.1 - 0.22 11.0 0.8 1 8.9 0.0 2.2 2 0 0 2 2 2 0 Shal-type voltage-gated potassium channels TMF_TATA_bd PF12325.3 EEQ76101.1 - 2e-45 153.4 11.4 2e-45 153.4 7.9 6.5 3 1 5 8 8 8 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EEQ76101.1 - 3.6e-21 74.7 18.8 3.6e-21 74.7 13.0 8.8 5 2 4 9 9 9 2 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 EEQ76101.1 - 0.0002 21.2 5.1 0.0002 21.2 3.6 5.2 3 1 2 5 5 5 1 Autophagy protein 16 (ATG16) IncA PF04156.9 EEQ76101.1 - 0.0026 17.3 6.4 0.0026 17.3 4.5 5.5 2 1 2 4 4 4 1 IncA protein Reo_sigmaC PF04582.7 EEQ76101.1 - 1.7 7.7 25.3 0.42 9.7 1.6 4.3 3 1 1 4 4 4 0 Reovirus sigma C capsid protein V-ATPase_H_N PF03224.9 EEQ76102.1 - 5.6e-79 265.4 0.1 8.9e-79 264.8 0.0 1.3 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EEQ76102.1 - 8.1e-41 138.6 0.0 3.3e-40 136.6 0.0 2.1 2 0 0 2 2 2 1 V-ATPase subunit H HEAT_2 PF13646.1 EEQ76102.1 - 0.097 12.9 0.4 0.51 10.6 0.0 2.4 3 0 0 3 3 3 0 HEAT repeats NCKAP5 PF15246.1 EEQ76102.1 - 0.21 10.9 0.1 0.32 10.3 0.1 1.2 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein Peptidase_M19 PF01244.16 EEQ76103.1 - 3e-10 39.5 0.1 0.00026 20.0 0.0 2.2 1 1 1 2 2 2 2 Membrane dipeptidase (Peptidase family M19) Thr_synth_N PF14821.1 EEQ76103.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Threonine synthase N terminus Acetyltransf_7 PF13508.1 EEQ76104.1 - 0.00016 21.7 0.0 0.00022 21.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEQ76104.1 - 0.0027 17.6 0.0 0.0037 17.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EEQ76104.1 - 0.066 12.9 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.1 EEQ76104.1 - 0.11 12.6 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEQ76104.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RHD3 PF05879.7 EEQ76105.1 - 0 1061.0 0.0 0 1060.7 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EEQ76105.1 - 2.4e-07 30.1 0.1 4.2e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EEQ76105.1 - 8.8e-07 28.8 0.0 1.7e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EEQ76105.1 - 0.00025 20.9 0.0 0.00056 19.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 EEQ76105.1 - 0.0012 18.8 0.0 0.0031 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EEQ76105.1 - 0.0029 18.0 0.0 0.0066 16.9 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 EEQ76105.1 - 0.076 12.0 0.0 0.19 10.7 0.0 1.7 1 0 0 1 1 1 0 Septin bZIP_1 PF00170.16 EEQ76106.1 - 0.00055 19.8 9.1 0.001 18.9 6.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor LIN37 PF15306.1 EEQ76106.1 - 0.023 14.7 3.8 0.041 13.8 2.6 1.4 1 0 0 1 1 1 0 LIN37 PAZ_siRNAbind PF12212.3 EEQ76106.1 - 0.04 13.5 0.0 0.09 12.4 0.0 1.6 1 0 0 1 1 1 0 Piwi/Argonaute/Zwille siRNA-binding domain DUF4407 PF14362.1 EEQ76106.1 - 0.099 11.5 1.9 0.14 11.0 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAP1_N PF04849.8 EEQ76106.1 - 0.14 11.0 6.0 0.21 10.4 4.1 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Atg14 PF10186.4 EEQ76106.1 - 0.49 9.2 7.3 0.68 8.8 5.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_Maf PF03131.12 EEQ76106.1 - 0.62 10.3 11.3 0.78 10.0 7.2 1.5 1 1 0 1 1 1 0 bZIP Maf transcription factor Phlebovirus_NSM PF07246.6 EEQ76106.1 - 0.77 8.8 3.5 1.1 8.4 2.4 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M IncA PF04156.9 EEQ76106.1 - 8.3 5.9 8.0 13 5.2 5.5 1.2 1 0 0 1 1 1 0 IncA protein GTP_EFTU PF00009.22 EEQ76107.1 - 2.4e-60 203.1 0.1 3.1e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EEQ76107.1 - 8.9e-24 83.5 0.1 7.5e-23 80.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EEQ76107.1 - 4.6e-17 61.9 3.0 1e-16 60.7 1.6 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEQ76107.1 - 5.2e-06 26.4 0.0 9.6e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EEQ76107.1 - 0.0012 18.4 0.7 0.003 17.1 0.2 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Miro PF08477.8 EEQ76107.1 - 0.0031 17.9 0.0 0.0053 17.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EEQ76107.1 - 0.054 12.9 0.3 4.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 EEQ76107.1 - 0.13 11.4 0.1 0.38 9.8 0.1 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region cobW PF02492.14 EEQ76107.1 - 0.22 10.9 1.1 0.78 9.1 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IF3_C PF00707.17 EEQ76108.1 - 4.8e-12 45.4 1.3 7.5e-12 44.8 0.9 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 EEQ76108.1 - 1.2e-05 24.7 1.8 1.7e-05 24.2 0.9 1.4 1 1 0 1 1 1 1 Mitochondrial translation initiation factor GDA1_CD39 PF01150.12 EEQ76109.1 - 4.3e-98 328.6 0.0 5.7e-98 328.2 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Asn_synthase PF00733.16 EEQ76110.1 - 1.7e-50 171.9 0.0 2.5e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EEQ76110.1 - 7.1e-26 90.3 0.0 1.4e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EEQ76110.1 - 3.2e-25 88.6 0.0 6.3e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EEQ76110.1 - 0.077 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Aluminium induced protein Sod_Fe_N PF00081.17 EEQ76112.1 - 7.9e-31 106.1 1.9 7.9e-31 106.1 1.3 1.9 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.13 EEQ76112.1 - 2.8e-30 104.2 0.5 5.1e-30 103.4 0.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain QueF_N PF14819.1 EEQ76112.1 - 0.14 12.2 0.1 0.58 10.2 0.0 1.9 2 0 0 2 2 2 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term DUF4598 PF15370.1 EEQ76113.1 - 5.1e-27 94.3 2.7 5.1e-27 94.3 1.9 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4598) Hep_59 PF07052.6 EEQ76113.1 - 0.03 14.6 1.5 0.03 14.6 1.0 2.5 2 1 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 IF4E PF01652.13 EEQ76114.1 - 2.1e-37 128.1 0.6 2.5e-37 127.9 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF2517 PF10725.4 EEQ76114.1 - 0.12 12.0 0.2 7.9 6.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2517) COMPASS-Shg1 PF05205.7 EEQ76115.1 - 3.7e-15 56.1 0.0 3.7e-15 56.1 0.0 2.6 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component shg1 PRP38_assoc PF12871.2 EEQ76115.1 - 7.9e-05 23.1 34.0 7.9e-05 23.1 23.6 4.3 2 1 1 4 4 4 2 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Cation_efflux PF01545.16 EEQ76117.1 - 1.6e-32 112.7 9.5 2.1e-32 112.3 6.6 1.1 1 0 0 1 1 1 1 Cation efflux family zf-RING_2 PF13639.1 EEQ76118.1 - 0.024 14.4 0.5 3.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Ring finger domain DUF2921 PF11145.3 EEQ76118.1 - 0.07 10.8 0.8 0.11 10.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) Baculo_E66 PF04850.7 EEQ76118.1 - 0.15 11.0 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Baculovirus E66 occlusion-derived virus envelope protein GCV_H PF01597.14 EEQ76119.1 - 1.7e-41 140.6 1.5 2.1e-41 140.4 1.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Ribosomal_S6 PF01250.12 EEQ76120.1 - 9.8e-09 34.9 0.0 1.3e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 Dynamin_N PF00350.18 EEQ76121.1 - 2.6e-43 147.7 0.0 4.8e-43 146.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EEQ76121.1 - 3.3e-09 35.9 0.1 5e-07 28.7 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 EEQ76121.1 - 0.00098 19.0 0.0 0.003 17.4 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEQ76121.1 - 0.0038 17.7 0.0 0.0086 16.5 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EEQ76121.1 - 0.035 14.1 0.8 0.65 9.9 0.0 3.0 3 1 0 3 3 3 0 AAA ATPase domain AAA_21 PF13304.1 EEQ76121.1 - 0.086 12.7 0.5 0.27 11.1 0.0 2.0 3 0 0 3 3 3 0 AAA domain APH PF01636.18 EEQ76123.1 - 5.9e-17 62.2 0.0 7.6e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ76123.1 - 1.2e-05 25.0 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EEQ76123.1 - 0.072 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.12 EEQ76123.1 - 0.13 11.3 0.0 2.5 7.0 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase Peptidase_C97 PF05903.9 EEQ76124.1 - 9.7e-06 25.4 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EEQ76124.1 - 0.045 13.7 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 Lecithin retinol acyltransferase DUF2887 PF11103.3 EEQ76124.1 - 0.09 12.3 0.1 0.099 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2887) DUF4105 PF13387.1 EEQ76124.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) FA_hydroxylase PF04116.8 EEQ76125.1 - 6.8e-12 45.7 24.3 6.8e-12 45.7 16.9 2.4 2 2 0 2 2 2 1 Fatty acid hydroxylase superfamily XPA_C PF05181.7 EEQ76126.1 - 1.7e-29 101.1 3.6 4.2e-29 99.8 2.5 1.7 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 EEQ76126.1 - 0.0085 15.7 3.5 0.0085 15.7 2.4 1.9 2 0 0 2 2 2 1 XPA protein N-terminal DZR PF12773.2 EEQ76126.1 - 0.18 11.6 3.3 0.68 9.7 1.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-AD PF07776.10 EEQ76126.1 - 0.24 11.4 3.6 0.12 12.3 0.9 1.7 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) ArfGap PF01412.13 EEQ76126.1 - 0.26 11.1 5.0 0.65 9.7 1.3 2.7 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf PIG-P PF08510.7 EEQ76128.1 - 3.5e-44 149.4 0.5 3.5e-44 149.4 0.3 1.7 2 0 0 2 2 2 1 PIG-P CDC45 PF02724.9 EEQ76128.1 - 0.025 12.6 0.0 0.032 12.2 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EEQ76128.1 - 4.7 5.0 7.7 5.8 4.7 5.4 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 EEQ76128.1 - 6.5 5.7 6.9 8.8 5.2 4.8 1.1 1 0 0 1 1 1 0 BUD22 Striatin PF08232.7 EEQ76129.1 - 3.2e-46 156.9 4.3 3.2e-46 156.9 3.0 2.2 2 0 0 2 2 2 1 Striatin family WD40 PF00400.27 EEQ76129.1 - 4.3e-33 111.9 22.2 1.8e-07 30.7 0.2 7.3 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 EEQ76129.1 - 0.026 14.2 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A BAF1_ABF1 PF04684.8 EEQ76129.1 - 1.4 7.7 16.5 2.3 6.9 11.4 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.4 EEQ76129.1 - 3.4 5.7 28.9 4.6 5.3 20.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Blt1 PF12754.2 EEQ76130.1 - 3.4e-70 237.0 3.6 1.3e-69 235.1 2.5 1.7 1 1 0 1 1 1 1 Cell-cycle control medial ring component DUF2340 PF10209.4 EEQ76130.1 - 0.022 14.9 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) DUF2407 PF10302.4 EEQ76130.1 - 0.11 12.6 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Nol1_Nop2_Fmu PF01189.12 EEQ76131.1 - 1.9e-95 319.4 0.0 2.6e-95 319.0 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EEQ76131.1 - 0.0027 17.7 0.0 0.0057 16.6 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Stap_Strp_toxin PF01123.15 EEQ76131.1 - 0.091 13.2 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, OB-fold domain UCH PF00443.24 EEQ76132.1 - 1.5e-14 53.7 0.0 2.5e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4_3 PF13920.1 EEQ76132.1 - 7.2e-13 48.0 10.9 1.2e-12 47.3 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MORN PF02493.15 EEQ76132.1 - 8.6e-13 47.2 20.9 0.00025 20.6 0.1 4.6 4 0 0 4 4 4 4 MORN repeat USP7_ICP0_bdg PF12436.3 EEQ76132.1 - 1.4e-06 27.7 0.0 3.9e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 zf-C3HC4_2 PF13923.1 EEQ76132.1 - 0.00025 21.0 13.1 0.00048 20.0 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ76132.1 - 0.0063 16.2 12.2 0.012 15.2 8.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain DS PF01916.12 EEQ76134.1 - 3.7e-145 482.6 0.0 4.3e-145 482.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 EEQ76134.1 - 0.035 13.2 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase Myb_DNA-binding PF00249.26 EEQ76135.1 - 2.3e-15 56.3 0.0 4.6e-08 32.9 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEQ76135.1 - 9.2e-05 22.4 1.9 0.11 12.6 0.0 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain DUF544 PF04424.8 EEQ76136.1 - 3e-08 33.4 0.0 5.6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF544) DUF2370 PF10176.4 EEQ76136.1 - 0.99 8.6 5.0 2.2 7.5 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) PM0188 PF11477.3 EEQ76137.1 - 0.00012 21.0 1.8 0.00014 20.8 1.2 1.0 1 0 0 1 1 1 1 Sialyltransferase PMO188 Mrr_N PF14338.1 EEQ76137.1 - 0.068 13.2 0.5 0.15 12.1 0.1 1.8 1 1 1 2 2 2 0 Mrr N-terminal domain NUDIX PF00293.23 EEQ76138.1 - 0.031 13.9 2.3 0.56 9.8 0.1 2.1 1 1 1 2 2 2 0 NUDIX domain Gcd10p PF04189.8 EEQ76139.1 - 3.8e-91 305.3 0.0 6.4e-91 304.5 0.0 1.4 1 0 0 1 1 1 1 Gcd10p family His_Phos_2 PF00328.17 EEQ76144.1 - 4.8e-11 42.5 0.1 2.7e-09 36.8 0.0 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) AAA PF00004.24 EEQ76145.1 - 2.8e-15 56.6 0.0 5e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EEQ76145.1 - 2.1e-13 50.0 0.0 5e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EEQ76145.1 - 5.3e-13 48.9 1.0 1.3e-12 47.7 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EEQ76145.1 - 1.1e-11 44.1 0.0 1.3e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EEQ76145.1 - 7.7e-07 29.3 0.4 5.2e-06 26.6 0.1 2.4 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 EEQ76145.1 - 6.3e-06 25.1 0.0 0.025 13.2 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus RuvB_N PF05496.7 EEQ76145.1 - 6.8e-06 25.3 0.1 6.2e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EEQ76145.1 - 8.9e-06 25.3 0.0 2.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain DNA_pol3_delta PF06144.8 EEQ76145.1 - 2.4e-05 23.9 0.0 5.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 EEQ76145.1 - 3.9e-05 23.7 0.2 0.0021 18.0 0.0 2.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 EEQ76145.1 - 6.3e-05 22.6 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEQ76145.1 - 7.9e-05 22.5 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEQ76145.1 - 8.6e-05 22.2 0.1 0.00029 20.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEQ76145.1 - 9.7e-05 22.1 0.4 0.00042 20.0 0.1 2.2 2 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EEQ76145.1 - 0.00032 20.3 0.0 0.00065 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EEQ76145.1 - 0.00053 18.9 0.0 0.0009 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.6 EEQ76145.1 - 0.0024 17.5 0.2 0.0085 15.7 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EEQ76145.1 - 0.0025 17.3 0.0 0.21 11.0 0.0 2.5 2 1 0 2 2 2 1 FtsK/SpoIIIE family AAA_28 PF13521.1 EEQ76145.1 - 0.0044 16.9 0.0 0.0077 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEQ76145.1 - 0.0068 17.2 0.0 0.013 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EEQ76145.1 - 0.009 15.4 0.1 0.023 14.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EEQ76145.1 - 0.011 14.7 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 EEQ76145.1 - 0.012 15.9 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EEQ76145.1 - 0.016 14.4 0.5 1.7 7.8 0.0 2.3 1 1 1 2 2 2 0 PhoH-like protein DEAD PF00270.24 EEQ76145.1 - 0.016 14.6 0.1 0.24 10.8 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.10 EEQ76145.1 - 0.023 14.5 0.0 0.79 9.5 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 EEQ76145.1 - 0.027 13.8 0.0 0.39 10.1 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_10 PF12846.2 EEQ76145.1 - 0.036 13.4 0.5 5.9 6.2 0.0 2.4 1 1 1 2 2 2 0 AAA-like domain TK PF00265.13 EEQ76145.1 - 0.043 13.3 0.1 0.1 12.1 0.0 1.6 2 0 0 2 2 1 0 Thymidine kinase Arch_ATPase PF01637.13 EEQ76145.1 - 0.079 12.6 0.0 0.13 11.8 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase Mg_chelatase PF01078.16 EEQ76145.1 - 0.091 11.9 1.9 0.17 10.9 0.1 2.5 2 1 1 3 3 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EEQ76145.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase P21-Arc PF04062.9 EEQ76146.1 - 4.1e-77 257.8 0.0 4.7e-77 257.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Hormone_3 PF00159.13 EEQ76146.1 - 0.08 12.9 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Pancreatic hormone peptide PetN PF03742.9 EEQ76148.1 - 0.4 10.3 3.2 0.84 9.2 2.2 1.5 1 0 0 1 1 1 0 PetN Pro_isomerase PF00160.16 EEQ76150.1 - 5.1e-37 127.4 0.0 1.1e-36 126.3 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GP38 PF05268.6 EEQ76150.1 - 0.014 14.8 0.3 0.014 14.8 0.2 1.8 2 0 0 2 2 2 0 Phage tail fibre adhesin Gp38 R3H PF01424.17 EEQ76151.1 - 3e-11 42.8 0.0 6.6e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 EEQ76151.1 - 1e-06 28.6 0.0 2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEQ76151.1 - 8.4e-06 25.3 0.1 1.6e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ76151.1 - 0.008 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_L_2 PF13656.1 EEQ76153.1 - 1.7e-22 78.6 0.0 2.4e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EEQ76153.1 - 4e-13 48.2 0.0 5.9e-13 47.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain CorA PF01544.13 EEQ76153.1 - 0.023 13.7 0.0 0.026 13.5 0.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein NMO PF03060.10 EEQ76154.1 - 6.3e-45 153.7 7.5 1.6e-44 152.4 5.2 1.6 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EEQ76154.1 - 1.1e-08 34.3 0.0 7.4e-06 25.0 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EEQ76154.1 - 1.5e-05 24.0 11.0 1.7e-05 23.8 7.1 1.4 1 1 1 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EEQ76154.1 - 0.00017 20.6 1.5 0.00027 19.9 1.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DrsE PF02635.10 EEQ76154.1 - 0.18 11.8 0.4 7 6.7 0.1 2.5 1 1 1 2 2 2 0 DsrE/DsrF-like family PBP1_TM PF14812.1 EEQ76155.1 - 0.14 12.5 22.4 0.51 10.6 2.3 3.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 EEQ76155.1 - 4.7 6.7 15.4 2.1 7.8 0.5 2.4 2 0 0 2 2 2 0 Nucleoplasmin AF-4 PF05110.8 EEQ76156.1 - 0.8 7.5 12.6 1 7.1 8.7 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF1117 PF06547.7 EEQ76156.1 - 4.6 7.3 8.2 11 6.1 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) DUF1180 PF06679.7 EEQ76157.1 - 0.16 11.8 0.7 0.38 10.6 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Cys_rich_VLP PF14194.1 EEQ76159.1 - 0.063 13.0 0.2 0.098 12.4 0.2 1.3 1 0 0 1 1 1 0 Cysteine-rich VLP Syndecan PF01034.15 EEQ76159.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain LRR_6 PF13516.1 EEQ76160.1 - 0.021 14.8 13.4 60 4.1 0.0 8.0 8 0 0 8 8 8 0 Leucine Rich repeat LRR_4 PF12799.2 EEQ76160.1 - 0.098 12.3 12.6 0.63 9.7 1.7 5.5 4 1 0 5 5 5 0 Leucine Rich repeats (2 copies) DUF2201_N PF13203.1 EEQ76160.1 - 4.3 6.4 9.0 7.2 5.6 6.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain LRR_2 PF07723.8 EEQ76160.1 - 9.8 6.8 10.1 11 6.6 0.1 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat SNF2_N PF00176.18 EEQ76161.1 - 3.7e-44 150.7 0.5 2e-43 148.2 0.4 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ76161.1 - 1.2e-12 47.4 0.0 3.7e-12 45.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EEQ76161.1 - 5.8e-07 29.0 6.0 1.2e-06 28.1 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ76161.1 - 3.8e-06 26.8 7.1 1.1e-05 25.3 4.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ76161.1 - 5.9e-05 22.8 7.3 0.00013 21.7 5.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEQ76161.1 - 5.9e-05 22.6 6.1 0.00012 21.6 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 EEQ76161.1 - 0.00024 20.9 0.0 0.00072 19.4 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.1 EEQ76161.1 - 0.0043 16.7 6.9 0.0078 15.9 4.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EEQ76161.1 - 0.0082 16.0 6.2 0.019 14.8 4.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EEQ76161.1 - 0.031 13.9 3.8 0.03 14.0 1.1 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_6 PF14835.1 EEQ76161.1 - 0.053 13.3 2.4 0.13 12.0 1.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_Tnp_IS91 PF14319.1 EEQ76161.1 - 0.058 12.9 1.2 0.12 11.8 0.8 1.5 1 0 0 1 1 1 0 Transposase zinc-binding domain Sec2p PF06428.6 EEQ76164.1 - 6.8e-09 35.4 11.6 6.8e-09 35.4 8.1 1.9 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p ATG16 PF08614.6 EEQ76164.1 - 0.0066 16.3 18.5 3 7.5 13.0 2.3 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Tektin PF03148.9 EEQ76164.1 - 0.035 12.6 8.9 0.063 11.8 3.9 2.0 2 0 0 2 2 2 0 Tektin family PAT1 PF09770.4 EEQ76164.1 - 0.041 12.1 13.6 0.049 11.8 9.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IncA PF04156.9 EEQ76164.1 - 0.05 13.1 16.0 0.67 9.5 9.1 2.4 2 1 0 2 2 2 0 IncA protein AAA_23 PF13476.1 EEQ76164.1 - 0.13 12.6 1.1 15 5.8 0.7 2.2 2 0 0 2 2 2 0 AAA domain Lebercilin PF15619.1 EEQ76164.1 - 0.16 11.3 16.0 1.5 8.1 7.3 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF4140 PF13600.1 EEQ76164.1 - 0.29 11.5 0.1 0.29 11.5 0.0 3.5 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Jnk-SapK_ap_N PF09744.4 EEQ76164.1 - 0.36 10.8 12.2 3.9 7.4 5.4 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 HAUS6_N PF14661.1 EEQ76164.1 - 0.41 9.9 12.1 0.038 13.3 3.9 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus LXG PF04740.7 EEQ76164.1 - 0.54 10.0 4.8 0.34 10.6 0.6 2.2 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF605 PF04652.11 EEQ76164.1 - 0.55 9.5 23.1 0.71 9.2 16.0 1.2 1 0 0 1 1 1 0 Vta1 like DUF3584 PF12128.3 EEQ76164.1 - 1.5 6.0 11.1 0.16 9.2 3.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.10 EEQ76164.1 - 2 7.5 10.2 1.2 8.1 4.9 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit TFIIA PF03153.8 EEQ76164.1 - 2.1 8.1 15.8 2.7 7.7 11.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myosin_tail_1 PF01576.14 EEQ76164.1 - 2.4 5.7 21.8 1.4 6.5 10.0 2.0 2 0 0 2 2 2 0 Myosin tail CAF-1_p150 PF11600.3 EEQ76164.1 - 2.4 7.4 15.0 0.2 10.9 6.2 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Cluap1 PF10234.4 EEQ76164.1 - 2.5 7.2 10.2 0.23 10.6 3.9 1.5 2 0 0 2 2 2 0 Clusterin-associated protein-1 CDC37_N PF03234.9 EEQ76164.1 - 2.7 8.3 5.5 5.3 7.3 1.3 2.2 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding TMF_DNA_bd PF12329.3 EEQ76164.1 - 3.7 7.4 17.3 0.27 11.0 0.3 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1682 PF07946.9 EEQ76164.1 - 4.3 6.0 8.6 6.5 5.4 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Atg14 PF10186.4 EEQ76164.1 - 4.7 6.0 15.2 2.1 7.2 6.8 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Toxin_39 PF15500.1 EEQ76164.1 - 6.1 7.0 7.4 1.5 8.9 0.1 2.6 2 1 0 2 2 2 0 Putative RNase-like toxin Prefoldin PF02996.12 EEQ76164.1 - 7.2 6.2 12.7 0.82 9.3 0.4 3.2 2 1 1 3 3 3 0 Prefoldin subunit Heme_oxygenase PF01126.15 EEQ76165.1 - 2.6e-06 27.1 0.0 0.001 18.6 0.0 2.8 1 1 1 2 2 2 1 Heme oxygenase Ribosomal_L32e PF01655.13 EEQ76166.1 - 7.9e-48 161.0 0.6 7.9e-48 161.0 0.4 1.6 1 1 1 2 2 2 1 Ribosomal protein L32 Sugar_tr PF00083.19 EEQ76167.1 - 1.1e-28 100.0 18.7 2.7e-16 59.1 0.5 4.0 2 1 2 4 4 4 4 Sugar (and other) transporter MFS_1 PF07690.11 EEQ76167.1 - 3e-10 39.3 13.7 1.9e-09 36.7 1.2 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEQ76167.1 - 0.016 13.4 2.3 0.028 12.6 0.3 1.9 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) PseudoU_synth_2 PF00849.17 EEQ76168.1 - 1.6e-25 89.8 0.0 2.9e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 EEQ76168.1 - 0.0011 18.3 0.1 0.002 17.5 0.1 1.4 1 0 0 1 1 1 1 S4 domain Auto_anti-p27 PF06677.7 EEQ76168.1 - 0.11 12.3 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) 4HBT PF03061.17 EEQ76169.1 - 7.1e-08 32.4 0.0 1.3e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 EEQ76169.1 - 0.00023 20.2 0.0 0.00044 19.2 0.1 1.4 2 0 0 2 2 2 1 Acyl-ACP thioesterase 4HBT_2 PF13279.1 EEQ76169.1 - 0.0043 17.4 0.0 0.0061 17.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily CTDII PF01556.13 EEQ76170.1 - 4e-24 84.3 0.1 8.4e-19 67.2 0.0 2.7 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 EEQ76170.1 - 1.6e-21 75.7 4.2 2.6e-21 75.0 2.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EEQ76170.1 - 9.7e-13 47.9 17.9 1.7e-12 47.1 12.4 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EEQ76170.1 - 0.015 14.9 6.5 0.3 10.7 0.9 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family GCC2_GCC3 PF07699.8 EEQ76170.1 - 6 6.5 11.4 11 5.7 1.1 2.6 2 0 0 2 2 2 0 GCC2 and GCC3 tRNA-synt_1c PF00749.16 EEQ76171.1 - 9.4e-75 251.1 0.0 3.5e-43 147.4 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain SSP160 PF06933.6 EEQ76171.1 - 0.068 11.1 9.4 0.1 10.5 6.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 EEQ76171.1 - 2.1 6.0 4.4 3.1 5.4 3.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MAP65_ASE1 PF03999.7 EEQ76172.1 - 1.7e-68 231.7 13.3 1.7e-68 231.7 9.2 2.3 2 1 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) JAB PF01398.16 EEQ76173.1 - 1e-27 96.1 0.1 1.7e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EEQ76173.1 - 8.6e-07 28.4 0.0 1.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain FAD_binding_4 PF01565.18 EEQ76176.1 - 4.4e-18 65.0 0.1 4.4e-18 65.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Chorion_2 PF03964.10 EEQ76176.1 - 0.0034 17.9 7.4 0.12 12.8 2.6 2.9 3 0 0 3 3 3 2 Chorion family 2 Fungal_trans PF04082.13 EEQ76177.1 - 4.3e-20 71.6 1.9 7.4e-20 70.9 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EEQ76177.1 - 2.4e-07 30.7 13.9 0.0001 22.4 4.0 3.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEQ76177.1 - 3.6e-05 23.7 13.2 0.0045 17.2 3.6 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ76177.1 - 0.00017 21.7 14.4 0.057 13.7 4.0 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type Elf1 PF05129.8 EEQ76177.1 - 5.3 6.8 11.7 6.6 6.5 5.7 2.7 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Ribosomal_S30 PF04758.9 EEQ76180.1 - 0.091 12.5 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein S30 RasGEF PF00617.14 EEQ76182.1 - 2e-62 210.2 0.3 4.2e-62 209.2 0.2 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EEQ76182.1 - 1.1e-27 96.1 0.3 2.5e-27 95.0 0.2 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 EEQ76182.1 - 8e-15 53.9 0.1 1.5e-14 53.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEQ76182.1 - 1.8e-12 46.6 0.1 5.2e-12 45.1 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EEQ76182.1 - 6.9e-11 41.4 0.0 2.1e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 EEQ76182.1 - 0.0011 18.7 0.0 0.0036 17.1 0.0 1.9 1 0 0 1 1 1 1 WW domain TPR_7 PF13176.1 EEQ76182.1 - 0.13 12.1 0.2 1.4 8.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat UPRTase PF14681.1 EEQ76185.1 - 8.7e-78 260.2 0.0 9.8e-78 260.0 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EEQ76185.1 - 8.6e-08 31.9 0.1 2.8e-07 30.3 0.1 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.1 EEQ76185.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain CRCB PF02537.10 EEQ76186.1 - 1.3e-31 108.9 20.6 2.7e-19 69.1 3.7 4.1 4 1 0 4 4 4 3 CrcB-like protein DUF3301 PF11743.3 EEQ76187.1 - 0.0016 17.9 0.3 0.0022 17.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3301) DUF4381 PF14316.1 EEQ76187.1 - 0.0042 17.1 0.0 0.005 16.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) T2SM PF04612.7 EEQ76187.1 - 0.0062 16.3 0.0 0.0075 16.0 0.0 1.1 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M DUF4234 PF14018.1 EEQ76187.1 - 0.03 14.0 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) Atrophin-1 PF03154.10 EEQ76187.1 - 0.068 11.3 0.5 0.086 10.9 0.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF485 PF04341.7 EEQ76187.1 - 0.093 12.4 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF485 MSC PF09402.5 EEQ76187.1 - 0.11 11.1 0.0 0.13 10.9 0.0 1.0 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain 7tm_1 PF00001.16 EEQ76187.1 - 0.12 11.4 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) RNA_pol_Rpc4 PF05132.9 EEQ76189.1 - 4.4e-29 101.1 0.1 4.4e-29 101.1 0.0 3.4 3 0 0 3 3 3 1 RNA polymerase III RPC4 Zn_clus PF00172.13 EEQ76190.1 - 0.00092 19.0 12.8 0.0019 18.0 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 EEQ76190.1 - 0.014 14.6 0.0 0.044 13.0 0.0 1.9 1 0 0 1 1 1 0 Histone chaperone domain CHZ Cyclin_N PF00134.18 EEQ76193.1 - 3.7e-43 146.1 0.5 6.4e-43 145.3 0.4 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EEQ76193.1 - 4.7e-22 78.1 0.1 1.2e-20 73.6 0.1 2.5 1 1 0 1 1 1 1 Cyclin, C-terminal domain HA2 PF04408.18 EEQ76194.1 - 3.4e-21 75.1 1.3 5.4e-21 74.5 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EEQ76194.1 - 8e-15 54.6 0.0 1.7e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.17 EEQ76194.1 - 4.9e-12 45.7 0.3 1.1e-11 44.6 0.2 1.6 1 0 0 1 1 1 1 RWD domain Helicase_C PF00271.26 EEQ76194.1 - 1.3e-10 40.9 0.0 3.1e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEQ76194.1 - 4.3e-10 39.3 0.2 7.9e-10 38.4 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EEQ76194.1 - 7.8e-05 21.7 0.0 0.00018 20.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EEQ76194.1 - 0.00028 21.0 0.1 0.00098 19.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain CoA_trans PF01144.18 EEQ76194.1 - 0.0018 17.4 0.0 0.0035 16.5 0.0 1.4 1 0 0 1 1 1 1 Coenzyme A transferase DND1_DSRM PF14709.1 EEQ76194.1 - 0.0057 16.9 0.9 0.026 14.8 0.6 2.2 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 FtsK_SpoIIIE PF01580.13 EEQ76194.1 - 0.0082 15.6 0.5 0.026 13.9 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_29 PF13555.1 EEQ76194.1 - 0.0093 15.4 0.0 0.03 13.8 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain PhoH PF02562.11 EEQ76194.1 - 0.021 14.0 0.0 0.049 12.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Zot PF05707.7 EEQ76194.1 - 0.025 14.0 0.0 0.071 12.5 0.0 1.7 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) KaiC PF06745.8 EEQ76194.1 - 0.033 13.3 0.0 0.062 12.4 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 EEQ76194.1 - 0.052 13.3 0.0 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain RecX PF02631.11 EEQ76194.1 - 0.15 12.2 2.8 9.4 6.4 0.0 3.3 2 1 1 3 3 3 0 RecX family AAA_23 PF13476.1 EEQ76194.1 - 0.22 11.8 1.1 0.83 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain DcpS_C PF11969.3 EEQ76195.1 - 1.9e-17 63.5 1.6 8.2e-17 61.5 1.1 1.9 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EEQ76195.1 - 3.6e-17 62.7 1.2 1.5e-16 60.7 0.8 1.9 1 1 0 1 1 1 1 HIT domain RNA_pol_N PF01194.12 EEQ76195.1 - 0.034 14.1 0.4 0.15 12.1 0.1 2.1 2 0 0 2 2 2 0 RNA polymerases N / 8 kDa subunit TRAP_alpha PF03896.11 EEQ76196.1 - 0.00015 20.9 0.3 0.001 18.1 0.1 2.1 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit GPI-anchored PF10342.4 EEQ76196.1 - 0.014 15.8 1.6 0.25 11.8 0.0 3.2 2 1 2 4 4 4 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family zf-CCCH_2 PF14608.1 EEQ76197.1 - 0.055 13.4 0.9 0.055 13.4 0.7 2.6 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type PSDC PF12588.3 EEQ76197.1 - 0.17 11.5 0.2 0.51 9.9 0.0 1.8 2 0 0 2 2 2 0 Phophatidylserine decarboxylase POT1 PF02765.12 EEQ76198.1 - 4.5e-17 62.3 0.0 8.2e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Allexi_40kDa PF05549.6 EEQ76198.1 - 0.012 14.9 0.3 0.025 13.8 0.1 1.5 2 0 0 2 2 2 0 Allexivirus 40kDa protein Arm PF00514.18 EEQ76199.1 - 1.4e-92 300.7 11.0 1.1e-13 50.4 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EEQ76199.1 - 1.9e-25 88.9 0.2 3.1e-09 36.9 0.0 5.6 1 1 6 7 7 7 5 HEAT repeats IBB PF01749.15 EEQ76199.1 - 8e-22 77.2 1.3 1.6e-21 76.2 0.9 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 EEQ76199.1 - 1.5e-21 76.2 5.6 5.9e-09 36.1 0.0 5.9 4 1 3 7 7 7 3 HEAT-like repeat HEAT PF02985.17 EEQ76199.1 - 4.5e-20 69.8 0.0 7.5e-06 25.6 0.0 6.6 6 0 0 6 6 6 4 HEAT repeat Arm_2 PF04826.8 EEQ76199.1 - 1.9e-11 43.5 0.0 0.00012 21.2 0.0 4.0 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.15 EEQ76199.1 - 0.00024 19.5 0.0 0.045 12.0 0.0 2.8 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 EEQ76199.1 - 0.00031 20.6 0.0 2 8.3 0.0 4.5 2 1 2 5 5 5 1 V-ATPase subunit H RICTOR_V PF14668.1 EEQ76199.1 - 0.0019 18.1 1.6 2.3 8.1 0.0 4.5 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 Proteasom_PSMB PF10508.4 EEQ76199.1 - 0.003 15.9 0.1 0.15 10.2 0.0 2.9 3 1 0 3 3 3 1 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 EEQ76199.1 - 0.0091 16.3 5.7 0.87 10.2 0.1 4.8 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.4 EEQ76199.1 - 0.011 15.4 0.0 13 5.5 0.0 3.8 3 1 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Glycos_trans_3N PF02885.12 EEQ76199.1 - 0.065 12.8 0.0 70 3.1 0.0 3.5 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain Mo25 PF08569.6 EEQ76199.1 - 0.19 10.7 0.0 0.31 10.0 0.0 1.4 1 0 0 1 1 1 0 Mo25-like SURF6 PF04935.7 EEQ76199.1 - 3 7.0 10.5 4.5 6.4 7.3 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 Amidase PF01425.16 EEQ76200.1 - 3.7e-101 339.1 0.0 4.3e-101 338.9 0.0 1.0 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.11 EEQ76201.1 - 1.1e-32 113.1 27.2 1.1e-32 113.1 18.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Yae1_N PF09811.4 EEQ76202.1 - 6.5e-11 41.5 0.5 1e-10 40.9 0.3 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal SCO1-SenC PF02630.9 EEQ76205.1 - 1.3e-60 204.0 0.0 1.7e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EEQ76205.1 - 0.0002 21.0 0.0 0.00037 20.1 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EEQ76205.1 - 0.0029 17.7 0.1 0.0051 16.8 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Aldo_ket_red PF00248.16 EEQ76206.1 - 5.8e-67 225.4 0.0 6.6e-67 225.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RRM_6 PF14259.1 EEQ76207.1 - 2e-13 50.1 0.0 1.4e-06 28.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEQ76207.1 - 6.7e-13 48.0 0.0 5.9e-05 22.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.13 EEQ76207.1 - 9.5e-10 37.4 1.0 1.8e-09 36.5 0.7 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch PF01585.18 EEQ76207.1 - 1.2e-09 37.7 1.9 3.2e-09 36.4 1.3 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EEQ76207.1 - 6.7e-06 25.8 0.5 6.7e-06 25.8 0.4 2.3 2 0 0 2 2 2 1 DExH-box splicing factor binding site RED_N PF07808.8 EEQ76207.1 - 0.0043 16.3 4.2 0.0043 16.3 2.9 1.9 2 0 0 2 2 2 1 RED-like protein N-terminal region Rad50_zn_hook PF04423.9 EEQ76207.1 - 0.033 13.6 0.4 0.11 12.0 0.3 1.9 1 0 0 1 1 1 0 Rad50 zinc hook motif RRM_5 PF13893.1 EEQ76207.1 - 0.058 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_3 PF13302.1 EEQ76209.1 - 2.4e-29 102.3 0.0 2.9e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEQ76209.1 - 0.00025 21.0 0.0 0.0009 19.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ76209.1 - 0.074 13.2 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain YgbB PF02542.11 EEQ76209.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 YgbB family DUF4523 PF15023.1 EEQ76210.1 - 0.026 14.0 0.1 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) RTA1 PF04479.8 EEQ76211.1 - 3.2e-41 141.2 4.5 3.2e-41 141.2 3.1 1.4 2 0 0 2 2 2 1 RTA1 like protein DUF308 PF03729.8 EEQ76211.1 - 5.2 7.1 17.9 0.63 10.0 2.7 3.5 3 1 0 3 3 3 0 Short repeat of unknown function (DUF308) DUF3433 PF11915.3 EEQ76212.1 - 5.6e-33 112.9 23.1 1.1e-28 99.2 0.9 3.9 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) OmpH PF03938.9 EEQ76214.1 - 0.0035 17.3 2.3 0.007 16.3 1.6 1.5 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Choline_kinase PF01633.15 EEQ76214.1 - 0.013 15.0 0.3 0.036 13.6 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase APH PF01636.18 EEQ76214.1 - 0.025 14.3 0.1 0.025 14.3 0.1 3.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.17 EEQ76214.1 - 0.075 12.3 0.1 0.075 12.3 0.0 1.8 2 0 0 2 2 2 0 RIO1 family GrpE PF01025.14 EEQ76214.1 - 0.14 11.6 7.9 0.086 12.3 3.8 1.8 2 0 0 2 2 2 0 GrpE DUF390 PF04094.9 EEQ76214.1 - 0.65 7.9 17.1 1 7.3 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF390) HAUS6_N PF14661.1 EEQ76214.1 - 2.7 7.2 10.2 5 6.4 7.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4192 PF13830.1 EEQ76214.1 - 4 6.9 14.6 6.8 6.2 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Phage_integrase PF00589.17 EEQ76215.1 - 0.00056 19.6 1.2 0.0032 17.1 0.8 2.1 1 1 0 1 1 1 1 Phage integrase family DUF3435 PF11917.3 EEQ76215.1 - 0.0019 17.0 0.0 0.0043 15.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) DUF4436 PF14494.1 EEQ76216.1 - 0.047 12.9 0.0 0.099 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) Ion_trans_2 PF07885.11 EEQ76217.1 - 2.2e-31 107.3 22.3 8e-18 63.9 4.2 3.2 3 0 0 3 3 3 2 Ion channel Flavi_NS2B PF01002.14 EEQ76217.1 - 0.22 11.1 3.5 0.41 10.2 0.0 2.9 3 0 0 3 3 3 0 Flavivirus non-structural protein NS2B AAA_10 PF12846.2 EEQ76218.1 - 9.7e-10 38.3 0.0 7.9e-06 25.5 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 EEQ76218.1 - 0.0003 20.3 0.0 0.0047 16.4 0.0 2.2 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA PF00004.24 EEQ76218.1 - 0.0017 18.5 0.1 0.0049 17.0 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEQ76218.1 - 0.0032 17.5 0.0 3.8 7.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EEQ76218.1 - 0.018 14.4 0.0 0.044 13.2 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Adeno_IVa2 PF02456.10 EEQ76218.1 - 0.038 12.6 0.0 0.059 12.0 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Arch_ATPase PF01637.13 EEQ76218.1 - 0.15 11.7 0.0 13 5.4 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase SUR7 PF06687.7 EEQ76219.1 - 3e-28 98.8 7.7 3.8e-28 98.4 5.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family NfeD PF01957.13 EEQ76219.1 - 0.25 11.4 2.7 0.26 11.4 0.3 2.0 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding RTA1 PF04479.8 EEQ76222.1 - 2.2e-15 56.7 2.7 3.3e-15 56.1 1.9 1.2 1 0 0 1 1 1 1 RTA1 like protein SNARE PF05739.14 EEQ76224.1 - 1.6e-17 62.9 1.2 5e-17 61.3 0.1 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EEQ76224.1 - 5.7e-15 55.3 2.7 3.4e-14 52.8 0.1 2.7 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 EEQ76224.1 - 0.0063 16.0 0.8 0.0063 16.0 0.5 2.1 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Sed5p PF11416.3 EEQ76224.1 - 0.023 14.1 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 Integral membrane protein Sed5p NPV_P10 PF05531.7 EEQ76224.1 - 0.09 13.0 2.5 24 5.2 0.1 3.6 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Syntaxin-18_N PF10496.4 EEQ76224.1 - 1.8 8.4 6.1 4.3 7.2 0.2 3.4 3 1 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus Trypan_PARP PF05887.6 EEQ76226.1 - 0.0012 18.7 21.9 0.0012 18.7 15.2 7.4 7 1 0 7 7 7 1 Procyclic acidic repetitive protein (PARP) Hrs_helical PF12210.3 EEQ76227.1 - 0.1 12.8 0.1 0.15 12.3 0.1 1.2 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Cupin_5 PF06172.6 EEQ76228.1 - 1.2e-34 119.2 0.0 1.4e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) RRM_1 PF00076.17 EEQ76230.1 - 2.3e-13 49.5 0.0 4.1e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ76230.1 - 4.1e-11 42.6 0.0 6.7e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ76230.1 - 7.5e-07 28.9 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mitofilin PF09731.4 EEQ76230.1 - 2.1 6.9 20.5 2.9 6.4 14.2 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Fmp27 PF10344.4 EEQ76233.1 - 4.4e-208 693.0 0.0 7e-208 692.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 EEQ76233.1 - 1.5e-167 558.1 0.5 4.8e-167 556.4 0.4 2.0 1 0 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EEQ76233.1 - 1.1e-158 528.6 0.3 1.1e-158 528.6 0.2 1.8 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EEQ76233.1 - 1.5e-58 197.0 0.6 3.9e-58 195.6 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.4 EEQ76233.1 - 2.4e-52 176.9 0.0 5.8e-52 175.7 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.4 EEQ76233.1 - 7.1e-35 119.5 0.0 4.3e-34 117.0 0.0 2.4 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain B-block_TFIIIC PF04182.7 EEQ76235.1 - 1.8e-19 69.3 0.1 4.8e-19 67.9 0.1 1.8 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC DUF3361 PF11841.3 EEQ76235.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) zf-DHHC PF01529.15 EEQ76236.1 - 0.0029 17.0 0.2 0.013 14.9 0.1 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase Rhomboid PF01694.17 EEQ76237.1 - 2.3e-36 124.9 10.0 4e-36 124.2 6.9 1.4 1 0 0 1 1 1 1 Rhomboid family DUF3317 PF11779.3 EEQ76238.1 - 1.4e-19 69.2 3.3 2e-19 68.7 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) SecE PF00584.15 EEQ76238.1 - 0.14 11.7 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex HTH_Tnp_Tc5 PF03221.11 EEQ76240.1 - 1.7e-07 30.9 0.0 2.6e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DAO PF01266.19 EEQ76241.1 - 2.2e-39 135.4 0.0 3e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEQ76241.1 - 0.00038 20.4 0.1 0.00075 19.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EEQ76241.1 - 0.033 12.8 0.1 3 6.3 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.12 EEQ76241.1 - 0.047 12.7 0.0 0.083 11.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 EEQ76241.1 - 0.083 12.7 0.2 5.4 6.8 0.1 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Kinetochor_Ybp2 PF08568.5 EEQ76242.1 - 2.8e-147 491.7 0.7 3.2e-147 491.4 0.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Pentapeptide_4 PF13599.1 EEQ76243.1 - 4.4e-08 32.8 3.1 3.6e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 Pentapeptide repeats (9 copies) PLDc_2 PF13091.1 EEQ76245.1 - 2.3e-14 53.2 0.0 3.9e-06 26.6 0.0 3.4 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.17 EEQ76245.1 - 6.7e-12 44.8 1.0 2.3e-05 24.0 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF4188 PF13826.1 EEQ76247.1 - 4.9e-28 97.5 0.2 9.8e-28 96.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dabb PF07876.7 EEQ76247.1 - 0.03 14.7 0.1 0.051 14.0 0.1 1.3 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain Dehydratase_hem PF13816.1 EEQ76247.1 - 0.032 13.2 0.1 0.047 12.7 0.1 1.2 1 0 0 1 1 1 0 Haem-containing dehydratase Cyanate_lyase PF02560.9 EEQ76248.1 - 1.8e-28 97.8 0.0 2.5e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain zf-C2H2_6 PF13912.1 EEQ76249.1 - 2.5e-09 36.7 18.9 0.23 11.3 0.0 6.2 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EEQ76249.1 - 2.2e-08 33.8 26.0 0.01 16.0 0.3 6.3 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ76249.1 - 1.4e-06 28.2 35.6 0.016 15.5 0.6 6.3 6 0 0 6 6 6 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EEQ76249.1 - 1.6e-05 24.9 24.0 0.005 16.9 0.2 6.0 5 1 1 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEQ76249.1 - 2.4e-05 24.3 24.2 0.11 12.7 0.2 6.2 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EEQ76249.1 - 0.0037 16.8 10.3 3.3 7.4 0.5 3.8 3 0 0 3 3 3 3 zinc-finger of a C2HC-type Rad50_zn_hook PF04423.9 EEQ76249.1 - 0.0084 15.5 0.5 0.0084 15.5 0.3 3.5 4 0 0 4 4 4 1 Rad50 zinc hook motif DUF629 PF04780.7 EEQ76249.1 - 0.26 9.7 14.1 0.093 11.2 2.6 3.6 2 2 2 4 4 4 0 Protein of unknown function (DUF629) DZR PF12773.2 EEQ76249.1 - 0.79 9.5 14.6 11 5.8 7.0 3.4 2 1 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.7 EEQ76249.1 - 4.9 7.0 16.2 2 8.2 2.5 3.8 2 1 2 4 4 4 0 zinc-ribbons YihI PF04220.7 EEQ76252.1 - 8.3 5.7 13.2 0.37 10.0 3.9 2.4 3 0 0 3 3 3 0 Der GTPase activator (YihI) DNA_pol_B PF00136.16 EEQ76253.1 - 1.1e-146 489.3 3.5 1.6e-146 488.7 2.4 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EEQ76253.1 - 1.5e-84 283.6 0.0 2.8e-84 282.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EEQ76253.1 - 9.6e-25 86.3 4.6 2.7e-24 84.9 3.2 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 EEQ76253.1 - 0.00027 20.7 0.1 0.0022 17.8 0.1 2.5 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 EEQ76253.1 - 0.002 17.7 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.17 EEQ76253.1 - 0.22 11.2 10.3 0.045 13.4 0.8 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Tyrosinase PF00264.15 EEQ76256.1 - 1.5e-43 149.5 1.9 1.9e-43 149.1 1.3 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Zn_clus PF00172.13 EEQ76257.1 - 2.2e-10 40.2 8.7 4.4e-10 39.2 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEQ76257.1 - 6.3e-09 34.9 1.6 9.9e-09 34.2 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.20 EEQ76258.1 - 2.3e-34 118.7 0.0 1.9e-21 76.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ76258.1 - 1.5e-12 47.1 0.0 1.4e-05 24.3 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase ADH_zinc_N PF00107.21 EEQ76259.1 - 4.7e-21 74.6 1.9 1.2e-20 73.3 0.5 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEQ76259.1 - 4e-08 34.1 0.0 7.7e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEQ76259.1 - 8e-08 32.0 0.0 6.9e-07 29.0 0.0 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 3-dmu-9_3-mt PF06983.8 EEQ76260.1 - 2.3e-34 118.2 0.9 4.8e-33 113.9 0.6 2.2 1 1 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase Glyco_hydro_47 PF01532.15 EEQ76261.1 - 1.6e-177 590.7 0.0 1.8e-177 590.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Syja_N PF02383.13 EEQ76263.1 - 1.7e-92 309.6 0.0 3.1e-92 308.7 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain DUF2454 PF10521.4 EEQ76264.1 - 2.1e-92 309.1 3.5 2.5e-92 308.8 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) PolyA_pol PF01743.15 EEQ76265.1 - 3.5e-25 88.6 0.2 1.1e-24 87.0 0.1 1.9 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EEQ76265.1 - 8.4e-07 28.4 0.0 2e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EEQ76265.1 - 0.0011 18.7 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative TRAPPC-Trs85 PF12739.2 EEQ76266.1 - 8.2e-120 400.2 0.1 4.3e-119 397.8 0.0 1.9 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Snf7 PF03357.16 EEQ76267.1 - 2.5e-17 62.7 16.0 2.5e-17 62.7 11.1 1.5 1 1 0 1 1 1 1 Snf7 zf-C3HC4_2 PF13923.1 EEQ76268.1 - 1.4e-08 34.6 19.9 4.3e-08 33.0 9.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EEQ76268.1 - 2.4e-08 33.6 4.5 2.4e-08 33.6 3.1 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.20 EEQ76268.1 - 1.3e-07 31.1 12.9 1.3e-07 31.1 9.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ76268.1 - 2.9e-07 30.0 18.1 5.7e-07 29.1 9.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EEQ76268.1 - 4.1e-07 29.7 18.0 8.3e-07 28.7 8.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEQ76268.1 - 1e-06 28.2 15.6 2e-06 27.3 7.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.22 EEQ76268.1 - 3.9e-06 26.2 0.0 8.2e-06 25.1 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-C3HC4_4 PF15227.1 EEQ76268.1 - 2.7e-05 23.9 15.8 4.7e-05 23.1 8.9 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EEQ76268.1 - 0.002 17.7 8.9 0.002 17.7 6.2 2.5 2 0 0 2 2 2 1 RING-type zinc-finger U-box PF04564.10 EEQ76268.1 - 0.0026 17.6 0.0 0.0069 16.3 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-rbx1 PF12678.2 EEQ76268.1 - 0.0047 16.9 5.7 0.0047 16.9 4.0 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger Mob_synth_C PF06463.8 EEQ76268.1 - 0.016 14.9 4.1 0.016 14.9 2.8 1.9 2 0 0 2 2 2 0 Molybdenum Cofactor Synthesis C zf-Apc11 PF12861.2 EEQ76268.1 - 0.016 15.0 2.1 0.016 15.0 1.5 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.9 EEQ76268.1 - 0.036 13.5 7.1 0.32 10.4 0.0 3.5 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-RING_4 PF14570.1 EEQ76268.1 - 0.038 13.5 14.5 0.046 13.3 7.4 2.7 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain zf-Di19 PF05605.7 EEQ76268.1 - 0.51 10.5 5.0 0.56 10.3 0.1 2.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CDC27 PF09507.5 EEQ76269.1 - 3.4e-106 356.0 24.6 4e-106 355.8 17.0 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF1237 PF06824.6 EEQ76270.1 - 6.4e-183 608.1 0.0 7.3e-183 607.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Rhodopsin_N PF10413.4 EEQ76270.1 - 0.095 12.3 0.1 0.26 10.9 0.1 1.7 1 0 0 1 1 1 0 Amino terminal of the G-protein receptor rhodopsin TaqI_C PF12950.2 EEQ76270.1 - 0.12 12.1 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain Nop14 PF04147.7 EEQ76271.1 - 0.00014 19.9 11.0 0.00023 19.2 7.6 1.4 1 0 0 1 1 1 1 Nop14-like family Lin-8 PF03353.10 EEQ76271.1 - 0.046 13.0 2.7 0.071 12.3 1.9 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RRM_1 PF00076.17 EEQ76271.1 - 0.055 13.1 0.0 0.82 9.3 0.0 2.5 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2890 PF11081.3 EEQ76271.1 - 0.4 10.6 14.3 1 9.3 9.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF3446 PF11928.3 EEQ76271.1 - 1.3 9.2 8.7 0.44 10.7 2.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) DUF1510 PF07423.6 EEQ76271.1 - 5 6.4 14.1 12 5.2 9.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BUD22 PF09073.5 EEQ76271.1 - 6.2 5.7 30.0 0.48 9.4 12.7 2.2 2 0 0 2 2 2 0 BUD22 NMD3 PF04981.8 EEQ76272.1 - 3e-75 252.3 5.1 4.5e-75 251.8 3.5 1.3 1 0 0 1 1 1 1 NMD3 family Nop14 PF04147.7 EEQ76272.1 - 5.5 4.7 16.9 7.3 4.3 11.7 1.1 1 0 0 1 1 1 0 Nop14-like family HypA PF01155.14 EEQ76272.1 - 5.6 6.6 11.0 4.2 7.1 1.2 3.0 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family Oligomerisation PF02410.10 EEQ76273.1 - 7.2e-05 22.7 0.0 0.017 15.1 0.0 2.6 2 1 0 2 2 2 2 Oligomerisation domain Pex2_Pex12 PF04757.9 EEQ76274.1 - 1.5e-57 194.6 1.2 1.9e-57 194.3 0.8 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EEQ76274.1 - 1.3e-07 31.3 3.2 2.2e-07 30.6 2.2 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EEQ76274.1 - 5.5e-07 29.5 2.7 9.4e-07 28.7 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ76274.1 - 2.4e-05 24.0 1.1 4e-05 23.3 0.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EEQ76274.1 - 0.0015 18.1 2.2 0.0024 17.4 1.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ76274.1 - 0.016 14.8 0.6 0.025 14.2 0.4 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mito_carr PF00153.22 EEQ76275.1 - 6.7e-60 198.8 0.0 3.8e-20 71.4 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein DDT PF02791.12 EEQ76276.1 - 3.3e-20 71.6 2.5 6.8e-20 70.6 1.7 1.6 1 0 0 1 1 1 1 DDT domain WAC_Acf1_DNA_bd PF10537.4 EEQ76276.1 - 6.5e-19 67.9 0.0 2.2e-18 66.3 0.0 1.9 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WHIM2 PF15613.1 EEQ76276.1 - 2.1e-12 46.4 0.3 4.4e-12 45.4 0.2 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 EEQ76276.1 - 1.3e-05 24.9 0.1 9.1e-05 22.1 0.1 2.3 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 3 WHIM1 PF15612.1 EEQ76276.1 - 2.3e-05 24.1 0.2 9.5e-05 22.1 0.1 2.1 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 Alg6_Alg8 PF03155.10 EEQ76278.1 - 4.7e-138 460.9 27.6 5.7e-138 460.6 19.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Lectin_leg-like PF03388.8 EEQ76279.1 - 7.5e-26 90.6 0.0 1.2e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Baculo_PEP_C PF04513.7 EEQ76279.1 - 0.0064 16.3 8.4 0.085 12.6 5.8 2.1 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus ISG65-75 PF11727.3 EEQ76279.1 - 0.0069 15.4 2.3 0.01 14.9 1.6 1.1 1 0 0 1 1 1 1 Invariant surface glycoprotein ApoLp-III PF07464.6 EEQ76279.1 - 0.0089 16.0 7.0 0.13 12.3 3.7 1.9 1 1 1 2 2 2 2 Apolipophorin-III precursor (apoLp-III) FlaC_arch PF05377.6 EEQ76279.1 - 0.015 15.1 6.5 0.076 12.9 1.8 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF342 PF03961.8 EEQ76279.1 - 0.021 13.2 0.8 0.031 12.7 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Lyase_8_N PF08124.6 EEQ76279.1 - 0.022 13.6 2.0 0.032 13.0 1.4 1.2 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain DUF3584 PF12128.3 EEQ76279.1 - 0.03 11.6 11.2 0.04 11.2 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Filament PF00038.16 EEQ76279.1 - 0.051 13.0 7.8 0.072 12.5 5.4 1.1 1 0 0 1 1 1 0 Intermediate filament protein TBPIP PF07106.8 EEQ76279.1 - 0.053 13.0 10.6 0.22 11.0 6.6 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) UPF0118 PF01594.11 EEQ76279.1 - 0.1 11.5 0.2 0.18 10.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF20 Utp12 PF04003.7 EEQ76279.1 - 0.21 11.4 3.0 0.42 10.5 0.4 2.1 1 1 1 2 2 2 0 Dip2/Utp12 Family Spectrin PF00435.16 EEQ76279.1 - 0.23 11.7 6.0 1.1 9.5 1.2 2.3 2 0 0 2 2 2 0 Spectrin repeat Tropomyosin_1 PF12718.2 EEQ76279.1 - 0.29 10.9 9.9 3.4 7.5 4.1 2.1 1 1 1 2 2 2 0 Tropomyosin like WXG100 PF06013.7 EEQ76279.1 - 0.55 10.2 3.6 0.76 9.8 0.8 2.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Syntaxin_2 PF14523.1 EEQ76279.1 - 0.63 10.1 14.5 0.85 9.6 0.6 2.3 1 1 1 2 2 2 0 Syntaxin-like protein Fib_alpha PF08702.5 EEQ76279.1 - 0.67 10.0 9.6 1.1 9.3 6.6 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1465 PF07323.7 EEQ76279.1 - 1.2 8.6 5.3 1.7 8.1 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) Phage_GP20 PF06810.6 EEQ76279.1 - 1.3 8.4 12.0 0.73 9.2 5.9 1.9 1 1 1 2 2 2 0 Phage minor structural protein GP20 Syntaxin PF00804.20 EEQ76279.1 - 1.6 8.9 13.8 2.2 8.4 7.9 2.2 1 1 1 2 2 2 0 Syntaxin DUF2681 PF10883.3 EEQ76279.1 - 1.9 8.7 16.8 0.26 11.4 4.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) DUF972 PF06156.8 EEQ76279.1 - 2 8.8 7.1 13 6.1 2.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Atg14 PF10186.4 EEQ76279.1 - 2.4 7.0 9.9 3.7 6.3 6.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Muted PF14942.1 EEQ76279.1 - 2.5 7.9 9.2 6.6 6.6 0.1 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein NPV_P10 PF05531.7 EEQ76279.1 - 2.6 8.3 9.3 3.2 8.0 2.9 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Fmp27_WPPW PF10359.4 EEQ76279.1 - 2.6 6.3 10.0 6.3 5.0 7.0 1.5 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain MerR-DNA-bind PF09278.6 EEQ76279.1 - 3.8 7.9 5.4 22 5.5 1.2 2.6 1 1 1 2 2 2 0 MerR, DNA binding EMP24_GP25L PF01105.19 EEQ76279.1 - 4.3 7.0 8.7 5.7 6.6 0.4 2.7 2 1 1 3 3 2 0 emp24/gp25L/p24 family/GOLD DUF1664 PF07889.7 EEQ76279.1 - 4.4 7.1 6.6 9.4 6.0 3.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 EEQ76279.1 - 6.9 6.6 6.0 17 5.3 1.1 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Phage_GPO PF05929.6 EEQ76279.1 - 8.1 5.5 8.4 13 4.9 5.1 1.8 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase PHD PF00628.24 EEQ76280.1 - 3.4e-17 61.8 18.3 2.6e-12 46.2 4.8 2.6 2 1 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.1 EEQ76280.1 - 0.0036 16.6 7.6 0.27 10.4 0.4 3.3 3 0 0 3 3 3 2 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 EEQ76280.1 - 0.4 10.4 9.0 3.4 7.4 1.0 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EEQ76280.1 - 3 7.6 12.5 0.19 11.4 1.9 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Peptidase_M24 PF00557.19 EEQ76281.1 - 3.5e-13 49.6 0.0 4.3e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Exo_endo_phos PF03372.18 EEQ76282.1 - 3.2e-12 46.9 0.2 3.9e-12 46.6 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EEQ76282.1 - 0.019 14.5 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase HSDR_N PF04313.9 EEQ76282.1 - 0.036 13.8 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) SNF5 PF04855.7 EEQ76283.1 - 4.6e-78 262.0 0.5 7.8e-78 261.3 0.4 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 HEAT_2 PF13646.1 EEQ76284.1 - 3.5e-08 33.6 2.5 5.7e-05 23.3 0.3 3.9 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EEQ76284.1 - 0.0001 22.1 0.1 0.064 13.3 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EEQ76284.1 - 0.0013 19.1 1.1 0.23 12.0 0.0 4.0 4 0 0 4 4 4 1 HEAT-like repeat TFIIF_alpha PF05793.7 EEQ76284.1 - 0.029 12.7 36.5 0.062 11.6 25.3 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 EEQ76284.1 - 0.16 9.9 29.7 0.42 8.4 20.6 1.7 1 0 0 1 1 1 0 Nop14-like family MFS_1 PF07690.11 EEQ76285.1 - 1.3e-40 139.2 37.3 1.3e-40 139.2 25.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ76285.1 - 3.2e-11 42.4 12.5 3.2e-11 42.4 8.7 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter DUF4231 PF14015.1 EEQ76285.1 - 0.091 12.7 0.2 0.091 12.7 0.1 4.4 4 2 0 4 4 4 0 Protein of unknown function (DUF4231) zf-RING_2 PF13639.1 EEQ76286.1 - 1.3e-09 37.7 1.0 1.3e-09 37.7 0.7 3.3 3 0 0 3 3 3 1 Ring finger domain PHD PF00628.24 EEQ76286.1 - 2.1e-09 36.9 5.7 2.1e-09 36.9 3.9 2.6 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EEQ76286.1 - 5e-07 28.9 3.7 1.2e-06 27.7 2.5 1.7 1 0 0 1 1 1 1 PHD-finger zf-RING_5 PF14634.1 EEQ76286.1 - 2.5e-06 27.0 0.5 2.5e-06 27.0 0.4 3.2 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EEQ76286.1 - 3e-06 26.7 0.6 3e-06 26.7 0.4 3.1 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEQ76286.1 - 4.3e-06 26.7 0.8 4.3e-06 26.7 0.6 2.8 3 0 0 3 3 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EEQ76286.1 - 9.4e-06 25.5 1.0 9.4e-06 25.5 0.7 3.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ76286.1 - 1.4e-05 24.6 0.6 1.4e-05 24.6 0.4 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEQ76286.1 - 0.00022 21.0 0.3 0.00022 21.0 0.2 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EEQ76286.1 - 0.0029 17.0 5.0 0.0074 15.8 0.5 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EEQ76286.1 - 0.028 14.0 0.2 0.028 14.0 0.1 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-PHD-like PF15446.1 EEQ76286.1 - 0.053 12.8 0.4 0.053 12.8 0.3 2.1 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain DZR PF12773.2 EEQ76286.1 - 0.23 11.2 4.7 0.14 12.0 0.4 2.6 1 1 1 2 2 2 0 Double zinc ribbon zf-RING-like PF08746.6 EEQ76286.1 - 0.47 10.4 11.2 3.4 7.7 1.3 2.7 2 0 0 2 2 2 0 RING-like domain zf-RING_UBOX PF13445.1 EEQ76286.1 - 0.85 9.3 7.0 0.78 9.5 0.1 3.0 3 0 0 3 3 3 0 RING-type zinc-finger Ndc1_Nup PF09531.5 EEQ76286.1 - 4.1 5.6 5.1 6.8 4.9 3.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Rad50_zn_hook PF04423.9 EEQ76286.1 - 6.4 6.3 6.8 24 4.4 0.0 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif Ribosomal_L37ae PF01780.14 EEQ76287.1 - 1.8e-40 136.7 9.4 2.2e-40 136.3 6.5 1.1 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EEQ76287.1 - 0.012 15.3 2.1 0.024 14.4 1.5 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 EEQ76287.1 - 0.31 10.5 0.1 0.31 10.5 0.1 1.9 2 0 0 2 2 2 0 A2L zinc ribbon domain Saccharop_dh PF03435.13 EEQ76288.1 - 2.1e-23 82.9 0.0 4e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EEQ76288.1 - 0.021 14.9 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 EEQ76288.1 - 0.027 14.7 0.0 0.078 13.2 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ribosomal_S16 PF00886.14 EEQ76288.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S16 Abhydrolase_6 PF12697.2 EEQ76289.1 - 5.4e-31 108.2 0.0 7e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ76289.1 - 1.7e-17 63.7 0.0 4.7e-17 62.3 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ76289.1 - 3.3e-13 49.6 0.0 1e-12 48.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EEQ76289.1 - 9.6e-06 25.3 0.0 1.9e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 EEQ76289.1 - 0.036 13.9 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Metallophos PF00149.23 EEQ76290.1 - 5.7e-07 29.1 0.2 1e-06 28.2 0.2 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEQ76290.1 - 0.0007 19.4 0.0 0.0011 18.7 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pinin_SDK_memA PF04696.8 EEQ76291.1 - 1.7e-11 43.8 23.6 1.8e-11 43.7 9.6 2.7 2 1 1 3 3 3 2 pinin/SDK/memA/ protein conserved region PHF5 PF03660.9 EEQ76292.1 - 1.4e-51 173.0 10.1 1.6e-51 172.8 7.0 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 EEQ76292.1 - 0.8 9.5 15.0 5.3 6.9 1.5 2.8 1 1 1 2 2 2 0 Double zinc ribbon Prok-RING_1 PF14446.1 EEQ76292.1 - 1.1 9.0 15.2 3.2 7.5 0.4 3.1 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PolC_DP2 PF03833.8 EEQ76292.1 - 4.6 4.7 5.4 4.5 4.7 3.7 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Cofilin_ADF PF00241.15 EEQ76293.1 - 1.7e-12 47.2 0.0 9.6e-06 25.5 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Mito_carr PF00153.22 EEQ76294.1 - 3.2e-70 231.9 2.2 5.7e-23 80.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4137 PF13593.1 EEQ76296.1 - 3e-76 256.4 13.6 2e-58 197.9 1.2 2.4 1 1 1 2 2 2 2 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 EEQ76296.1 - 5e-09 35.8 3.1 5e-09 35.8 2.2 2.1 1 1 1 2 2 2 1 Sodium Bile acid symporter family Mem_trans PF03547.13 EEQ76296.1 - 9.5e-06 24.1 2.4 3e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Membrane transport protein DUF373 PF04123.8 EEQ76296.1 - 0.71 8.8 4.0 0.21 10.5 0.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF1682 PF07946.9 EEQ76297.1 - 0.89 8.3 6.6 1.3 7.8 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Pex16 PF08610.5 EEQ76297.1 - 2.6 6.9 10.5 0.16 10.8 2.4 2.3 2 1 1 3 3 3 0 Peroxisomal membrane protein (Pex16) TATR PF03430.8 EEQ76297.1 - 3.9 6.0 5.3 6.3 5.3 3.7 1.3 1 0 0 1 1 1 0 Trans-activating transcriptional regulator CAF1 PF04857.15 EEQ76298.1 - 1.2e-21 77.1 0.0 2.2e-21 76.3 0.0 1.5 1 1 0 1 1 1 1 CAF1 family ribonuclease FAM212 PF15342.1 EEQ76298.1 - 0.0025 17.3 0.0 0.0095 15.5 0.0 2.0 1 0 0 1 1 1 1 FAM212 family MRP-L46 PF11788.3 EEQ76299.1 - 8.3e-35 119.8 0.5 1.5e-34 118.9 0.3 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EEQ76299.1 - 0.059 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 NUDIX domain Cript PF10235.4 EEQ76300.1 - 5.8e-35 119.5 9.4 5.8e-35 119.5 6.5 1.4 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT zf-ribbon_3 PF13248.1 EEQ76300.1 - 0.0015 17.6 9.5 0.034 13.3 1.8 3.3 2 1 1 3 3 3 1 zinc-ribbon domain DZR PF12773.2 EEQ76300.1 - 0.007 16.1 16.1 0.047 13.5 7.4 2.8 1 1 1 2 2 2 2 Double zinc ribbon zinc_ribbon_2 PF13240.1 EEQ76300.1 - 0.014 14.9 9.5 1.3 8.6 3.8 3.4 2 1 0 2 2 2 0 zinc-ribbon domain LIM PF00412.17 EEQ76300.1 - 0.14 12.2 9.9 5.7 7.0 0.1 3.3 2 1 1 3 3 3 0 LIM domain zf-AD PF07776.10 EEQ76300.1 - 0.56 10.2 8.2 3.3 7.7 2.2 2.5 2 1 0 2 2 2 0 Zinc-finger associated domain (zf-AD) zf-HYPF PF07503.7 EEQ76300.1 - 3.4 7.1 10.2 6.6 6.2 3.6 2.4 2 0 0 2 2 2 0 HypF finger RRN7 PF11781.3 EEQ76300.1 - 4.3 6.9 10.9 0.63 9.5 2.6 2.7 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF2039 PF10217.4 EEQ76300.1 - 4.3 7.4 18.3 3 7.9 8.9 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf-FPG_IleRS PF06827.9 EEQ76300.1 - 7.7 6.2 10.8 10 5.9 0.1 3.0 3 1 0 3 3 3 0 Zinc finger found in FPG and IleRS DUF581 PF04570.9 EEQ76300.1 - 7.8 5.8 13.0 10 5.5 1.3 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF581) PARG_cat PF05028.9 EEQ76301.1 - 1e-31 110.4 0.0 1.5e-26 93.4 0.0 2.1 2 0 0 2 2 2 2 Poly (ADP-ribose) glycohydrolase (PARG) DUF1349 PF07081.6 EEQ76302.1 - 3.1e-18 65.8 0.0 7e-08 32.0 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF1349) AMP-binding PF00501.23 EEQ76304.1 - 7.8e-84 281.4 0.0 1.3e-83 280.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EEQ76304.1 - 2.4e-73 246.6 0.0 1.2e-38 132.7 0.0 4.3 4 1 0 4 4 4 3 Condensation domain PP-binding PF00550.20 EEQ76304.1 - 5.8e-25 87.3 3.4 5.6e-12 45.7 0.2 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEQ76304.1 - 5.8e-08 33.5 2.1 2.2e-07 31.7 0.5 2.9 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Trp_DMAT PF11991.3 EEQ76305.1 - 2.9e-107 359.0 0.0 3.4e-107 358.7 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Abhydrolase_2 PF02230.11 EEQ76306.1 - 1.9e-22 79.8 0.1 4.9e-08 32.6 0.0 4.1 2 1 1 3 3 3 3 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EEQ76306.1 - 0.0011 18.9 0.4 0.013 15.4 0.3 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family AF0941-like PF14591.1 EEQ76309.1 - 0.0041 17.1 0.7 0.0073 16.3 0.5 1.4 1 0 0 1 1 1 1 AF0941-like Baculo_PEP_C PF04513.7 EEQ76309.1 - 0.0096 15.7 3.9 0.015 15.0 2.7 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus IFT57 PF10498.4 EEQ76309.1 - 0.07 11.8 3.2 0.1 11.3 2.2 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Rho_Binding PF08912.6 EEQ76309.1 - 0.13 12.5 4.4 0.2 11.9 2.3 1.8 1 1 1 2 2 2 0 Rho Binding GLE1 PF07817.8 EEQ76309.1 - 0.25 10.2 1.1 0.38 9.6 0.8 1.2 1 0 0 1 1 1 0 GLE1-like protein Snapin_Pallidin PF14712.1 EEQ76309.1 - 0.68 10.2 5.1 4.8 7.5 2.2 2.1 1 1 1 2 2 2 0 Snapin/Pallidin NOC3p PF07540.6 EEQ76310.1 - 5.9e-33 113.0 1.6 7.7e-33 112.6 0.0 2.1 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.12 EEQ76310.1 - 1.5e-28 99.3 0.0 4.4e-28 97.7 0.0 1.8 1 0 0 1 1 1 1 CBF/Mak21 family UPF0113 PF03657.8 EEQ76311.1 - 1.5e-06 27.9 0.0 2.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 EEQ76311.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 PUA domain Cullin_binding PF03556.10 EEQ76312.1 - 3.6e-31 107.7 1.1 5.4e-31 107.1 0.8 1.3 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 EEQ76312.1 - 1.2e-14 53.5 0.0 9.6e-14 50.6 0.0 2.2 2 0 0 2 2 2 1 UBA-like domain UBA PF00627.26 EEQ76312.1 - 0.12 12.3 0.0 0.6 10.0 0.0 2.1 2 0 0 2 2 2 0 UBA/TS-N domain SWIB PF02201.13 EEQ76314.1 - 7.2e-15 54.4 0.0 1.5e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DUF3697 PF12478.3 EEQ76314.1 - 0.045 13.4 0.2 0.13 11.9 0.1 1.8 2 0 0 2 2 2 0 Ubiquitin-associated protein 2 Band_7 PF01145.20 EEQ76315.1 - 1.3e-28 100.0 1.7 1.9e-28 99.5 1.2 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EEQ76315.1 - 0.047 13.2 0.1 0.069 12.6 0.1 1.2 1 0 0 1 1 1 0 SPFH domain-Band 7 family Perilipin PF03036.11 EEQ76317.1 - 0.018 13.8 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Perilipin family PucR PF07905.6 EEQ76317.1 - 0.055 13.0 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Ndc80_HEC PF03801.8 EEQ76319.1 - 0.017 14.5 0.3 0.021 14.2 0.2 1.1 1 0 0 1 1 1 0 HEC/Ndc80p family IcmL PF11393.3 EEQ76319.1 - 0.054 13.4 0.2 0.079 12.8 0.1 1.4 1 1 0 1 1 1 0 Macrophage killing protein with similarity to conjugation protein Coatomer_b_Cpla PF14806.1 EEQ76319.1 - 0.072 12.7 0.1 0.097 12.3 0.0 1.2 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform PTR2 PF00854.16 EEQ76321.1 - 1.2e-53 182.2 14.0 8.7e-29 100.4 5.3 2.2 2 0 0 2 2 2 2 POT family DUF2689 PF10894.3 EEQ76322.1 - 0.13 12.0 0.3 0.22 11.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2689) Cytochrom_B558a PF05038.8 EEQ76323.1 - 0.42 10.2 4.1 3.5 7.2 0.0 3.5 1 1 3 4 4 4 0 Cytochrome Cytochrome b558 alpha-subunit R_equi_Vir PF05526.6 EEQ76323.1 - 0.94 9.0 4.9 4.9 6.7 0.3 3.1 1 1 3 4 4 4 0 Rhodococcus equi virulence-associated protein Glyco_hydro_18 PF00704.23 EEQ76324.1 - 1.9e-91 307.0 0.8 2.3e-91 306.7 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 POC1 PF10450.4 EEQ76324.1 - 0.13 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 POC1 chaperone ubiquitin PF00240.18 EEQ76325.1 - 1.6e-34 117.0 0.9 2.8e-34 116.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EEQ76325.1 - 4e-28 96.9 2.3 8.3e-28 95.9 1.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EEQ76325.1 - 5.9e-20 70.7 0.7 1e-19 69.9 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EEQ76325.1 - 8.7e-06 25.9 0.2 4e-05 23.7 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EEQ76325.1 - 0.00012 21.7 0.1 0.0002 21.1 0.0 1.3 1 1 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EEQ76325.1 - 0.00069 19.4 0.7 0.0015 18.4 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EEQ76325.1 - 0.0041 17.2 0.4 0.0057 16.8 0.3 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.16 EEQ76325.1 - 0.014 15.2 0.5 0.022 14.6 0.3 1.4 1 0 0 1 1 1 0 IBR domain DUF2870 PF11069.3 EEQ76325.1 - 0.047 13.7 0.7 0.1 12.6 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 EEQ76325.1 - 0.09 11.0 2.4 2.2 6.4 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain zf-H2C2_2 PF13465.1 EEQ76326.1 - 9.5e-10 38.2 12.4 0.00018 21.5 0.1 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EEQ76326.1 - 2.6e-09 36.8 18.2 0.0068 16.6 4.9 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ76326.1 - 2.5e-05 24.2 15.0 0.046 14.0 0.1 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EEQ76326.1 - 0.044 13.6 0.3 0.044 13.6 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Ribonuclease_T2 PF00445.13 EEQ76327.1 - 1.1e-33 116.4 0.0 1.7e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family 4HBT_3 PF13622.1 EEQ76328.1 - 4.4e-48 164.2 0.2 5e-48 164.0 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF155 PF02582.9 EEQ76329.1 - 2e-45 154.8 0.0 3e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Clathrin PF00637.15 EEQ76330.1 - 1.1e-18 67.1 2.9 1.4e-18 66.8 0.0 2.5 3 0 0 3 3 3 1 Region in Clathrin and VPS WD40 PF00400.27 EEQ76330.1 - 0.00015 21.5 2.7 0.02 14.7 1.4 3.2 3 1 0 3 3 2 1 WD domain, G-beta repeat zf-RING_5 PF14634.1 EEQ76330.1 - 0.02 14.6 1.5 0.042 13.5 1.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Daxx PF03344.10 EEQ76330.1 - 0.034 12.6 1.3 0.069 11.6 0.9 1.5 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EEQ76330.1 - 0.083 10.8 6.1 0.083 10.8 2.7 1.9 2 0 0 2 2 2 0 Nop14-like family zf-RING_2 PF13639.1 EEQ76330.1 - 0.096 12.5 2.5 0.23 11.2 1.7 1.6 1 0 0 1 1 1 0 Ring finger domain CDC45 PF02724.9 EEQ76330.1 - 0.13 10.2 0.5 0.2 9.6 0.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Vps39_2 PF10367.4 EEQ76330.1 - 0.22 11.7 0.0 0.58 10.3 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 PBP1_TM PF14812.1 EEQ76330.1 - 0.43 10.9 7.7 1.8 8.8 5.3 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 EEQ76330.1 - 1.9 8.7 12.1 5.8 7.2 8.4 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 EEQ76330.1 - 6.6 6.2 10.8 13 5.2 7.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 EEQ76330.1 - 7.6 5.6 7.0 14 4.8 4.9 1.3 1 0 0 1 1 1 0 NOA36 protein CP2 PF04516.10 EEQ76334.1 - 1.1e-87 293.0 0.0 1.6e-87 292.4 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Metallopep PF12044.3 EEQ76338.1 - 2.2e-150 500.7 0.0 2.8e-150 500.4 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family GST_N_3 PF13417.1 EEQ76340.1 - 7.3e-09 35.7 0.1 1.5e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEQ76340.1 - 2.3e-07 30.6 0.0 5.7e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEQ76340.1 - 5.1e-06 26.2 0.4 1.1e-05 25.1 0.2 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.11 EEQ76341.1 - 1e-14 54.0 17.6 3.4e-09 35.8 0.2 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily PepSY_TM PF03929.11 EEQ76343.1 - 0.11 12.9 0.2 0.11 12.9 0.1 2.3 2 0 0 2 2 2 0 PepSY-associated TM helix DJ-1_PfpI PF01965.19 EEQ76344.1 - 6.6e-16 58.0 0.0 9.5e-16 57.5 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DNA_ligase_A_M PF01068.16 EEQ76345.1 - 3.5e-48 163.6 0.0 1.8e-45 154.7 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EEQ76345.1 - 1.3e-41 142.3 0.0 2.5e-41 141.4 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EEQ76345.1 - 8e-20 71.0 0.0 3.5e-19 69.0 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RINT1_TIP1 PF04437.8 EEQ76346.1 - 2.1e-179 597.2 3.3 1.8e-178 594.1 0.0 2.1 2 0 0 2 2 2 1 RINT-1 / TIP-1 family His_Phos_1 PF00300.17 EEQ76346.1 - 5.7e-05 23.2 2.5 0.23 11.5 0.2 3.3 3 1 1 4 4 4 2 Histidine phosphatase superfamily (branch 1) PAS_7 PF12860.2 EEQ76346.1 - 0.1 12.6 1.2 0.47 10.4 0.5 2.2 2 0 0 2 2 2 0 PAS fold L31 PF09784.4 EEQ76346.1 - 0.11 12.5 2.1 0.75 9.8 1.2 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 DUF668 PF05003.7 EEQ76346.1 - 0.19 11.9 1.9 0.27 11.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF668) ALMT PF11744.3 EEQ76346.1 - 0.24 9.9 4.0 0.42 9.2 2.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3407 PF11887.3 EEQ76346.1 - 0.25 10.5 2.5 0.59 9.3 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3407) Pyridoxal_deC PF00282.14 EEQ76347.1 - 1.9e-68 230.6 0.0 2.6e-67 226.8 0.0 2.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EEQ76347.1 - 5.3e-06 25.7 0.0 8.4e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EEQ76347.1 - 1.8e-05 23.6 0.0 3.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V PUF PF00806.14 EEQ76348.1 - 4.4e-13 47.9 0.0 2.4 7.8 0.0 7.7 8 0 0 8 8 8 5 Pumilio-family RNA binding repeat RCC1 PF00415.13 EEQ76349.1 - 8.4e-31 105.9 4.1 8.5e-06 25.8 0.0 8.0 9 0 0 9 9 9 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EEQ76349.1 - 7.4e-10 38.1 1.1 1.1e-08 34.3 0.1 7.1 9 0 0 9 9 9 3 Regulator of chromosome condensation (RCC1) repeat Sec34 PF04136.10 EEQ76351.1 - 1.1e-17 64.2 1.0 2.4e-15 56.6 0.3 2.8 1 1 1 2 2 2 2 Sec34-like family SYCE1 PF15233.1 EEQ76351.1 - 0.046 13.6 0.3 0.21 11.4 0.1 2.1 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 Pkinase PF00069.20 EEQ76352.1 - 2.4e-63 213.7 0.0 4.5e-63 212.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ76352.1 - 5.5e-45 153.4 0.0 8.3e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ76352.1 - 8.6e-10 38.0 0.0 7.6e-08 31.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EEQ76352.1 - 0.00066 18.7 0.0 0.0018 17.4 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-H2C2_2 PF13465.1 EEQ76355.1 - 2.2e-05 24.5 3.3 2.2e-05 24.5 2.3 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 EEQ76355.1 - 3.3e-05 23.9 2.7 3.3e-05 23.9 1.9 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EEQ76355.1 - 0.0015 18.6 0.7 0.0039 17.3 0.5 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EEQ76355.1 - 0.0017 18.5 0.7 0.0017 18.5 0.5 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger Fork_head PF00250.13 EEQ76357.1 - 7.6e-37 125.2 2.0 1.5e-36 124.2 1.4 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EEQ76357.1 - 1.1e-07 31.8 0.1 2.2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain Cwf_Cwc_15 PF04889.7 EEQ76357.1 - 0.027 14.1 0.7 0.053 13.2 0.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Metallopep PF12044.3 EEQ76361.1 - 8.5e-134 446.1 0.0 1.1e-133 445.8 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_2 PF13574.1 EEQ76361.1 - 0.002 18.2 0.1 0.0038 17.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EEQ76361.1 - 0.0068 16.3 0.2 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EEQ76361.1 - 0.0087 16.5 0.1 0.021 15.3 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EEQ76361.1 - 0.022 14.2 0.3 0.039 13.4 0.2 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EEQ76361.1 - 0.063 12.1 0.7 0.11 11.3 0.5 1.3 1 0 0 1 1 1 0 Peptidase M66 Glyoxalase_2 PF12681.2 EEQ76362.1 - 0.094 13.3 0.0 0.78 10.3 0.0 2.4 3 0 0 3 3 3 0 Glyoxalase-like domain Cytochrom_c3_2 PF14537.1 EEQ76365.1 - 0.033 14.5 1.7 0.041 14.2 1.2 1.3 1 0 0 1 1 1 0 Cytochrome c3 AF0941-like PF14591.1 EEQ76365.1 - 0.036 14.1 3.6 0.05 13.6 2.5 1.3 1 1 0 1 1 1 0 AF0941-like Thioredoxin_2 PF13098.1 EEQ76365.1 - 0.11 12.7 3.5 1.7 8.8 2.4 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EEQ76365.1 - 0.22 11.5 1.4 4.2 7.4 0.3 2.5 1 1 1 2 2 2 0 Thioredoxin-like Moulting_cycle PF04870.11 EEQ76365.1 - 0.28 10.2 6.0 0.3 10.1 4.2 1.0 1 0 0 1 1 1 0 Moulting cycle MSG PF02349.10 EEQ76365.1 - 0.67 9.9 8.9 0.82 9.6 6.1 1.3 1 1 0 1 1 1 0 Major surface glycoprotein Fungal_trans_2 PF11951.3 EEQ76366.1 - 0.096 11.2 0.0 0.1 11.1 0.0 1.0 1 0 0 1 1 1 0 Fungal specific transcription factor domain PHD PF00628.24 EEQ76368.1 - 5.4e-09 35.6 10.9 9.8e-09 34.7 7.5 1.5 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EEQ76368.1 - 7.1e-05 23.0 0.0 0.00017 21.8 0.0 1.7 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PsbK PF02533.10 EEQ76370.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Photosystem II 4 kDa reaction centre component DUF1191 PF06697.7 EEQ76371.1 - 0.03 13.1 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) SKG6 PF08693.5 EEQ76371.1 - 0.13 11.5 1.6 0.38 10.1 1.1 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MgtE PF01769.11 EEQ76372.1 - 0.011 16.0 0.1 0.013 15.7 0.1 1.1 1 0 0 1 1 1 0 Divalent cation transporter EB1 PF03271.12 EEQ76376.1 - 1.2e-17 63.7 0.3 2e-17 62.9 0.2 1.4 1 0 0 1 1 1 1 EB1-like C-terminal motif Herpes_UL6 PF01763.11 EEQ76376.1 - 0.022 12.9 0.0 0.028 12.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like WD40 PF00400.27 EEQ76377.1 - 2.1e-41 138.3 13.3 5.7e-10 38.6 0.1 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EEQ76377.1 - 8.3e-09 35.0 0.4 1.8e-08 34.0 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ76377.1 - 0.00019 20.9 0.0 0.00038 20.0 0.0 1.5 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 EEQ76377.1 - 0.00049 19.6 0.3 0.024 14.0 0.2 2.6 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.16 EEQ76377.1 - 0.01 15.3 0.7 14 5.4 0.0 3.7 3 0 0 3 3 3 0 PQQ enzyme repeat PQQ_3 PF13570.1 EEQ76377.1 - 0.055 13.7 2.5 1.7e+02 2.6 0.0 5.3 6 1 1 7 7 7 0 PQQ-like domain Nup160 PF11715.3 EEQ76377.1 - 0.16 10.0 0.9 4.5 5.2 0.0 3.0 2 1 2 4 4 4 0 Nucleoporin Nup120/160 GFO_IDH_MocA PF01408.17 EEQ76380.1 - 9.6e-09 35.8 0.2 2e-08 34.8 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold E1-E2_ATPase PF00122.15 EEQ76382.1 - 7.9e-60 201.7 0.5 1.7e-59 200.6 0.4 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEQ76382.1 - 6.7e-44 149.5 7.5 6.7e-44 149.5 5.2 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEQ76382.1 - 3e-28 99.7 0.0 5.8e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEQ76382.1 - 4.1e-18 65.1 0.0 8.3e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EEQ76382.1 - 2.1e-13 50.8 0.0 4.8e-13 49.7 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEQ76382.1 - 1.8e-08 33.7 0.1 9.6e-08 31.3 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EEQ76382.1 - 1.8e-05 24.4 0.1 0.0012 18.5 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 EEQ76382.1 - 0.061 13.2 0.0 0.061 13.2 0.0 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3325) Herpes_UL51 PF04540.8 EEQ76382.1 - 0.088 12.3 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus UL51 protein P16-Arc PF04699.9 EEQ76383.1 - 2.6e-57 193.1 0.0 3e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Methyltransf_11 PF08241.7 EEQ76384.1 - 4.4e-09 36.7 0.0 1.1e-08 35.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ76384.1 - 1.2e-07 31.5 0.0 1.8e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ76384.1 - 7.2e-06 26.3 0.0 1.6e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ76384.1 - 0.0021 17.6 0.0 0.0071 15.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ76384.1 - 0.031 14.6 0.0 0.1 12.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ76384.1 - 0.05 12.6 0.0 0.079 12.0 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Dynactin_p62 PF05502.8 EEQ76385.1 - 4e-182 606.3 0.0 5e-182 605.9 0.0 1.0 1 0 0 1 1 1 1 Dynactin p62 family Ribosomal_S7e PF01251.13 EEQ76386.1 - 2.9e-80 268.2 0.2 3.3e-80 268.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e XFP_N PF09364.5 EEQ76387.1 - 2.7e-100 335.5 2.6 3.6e-49 167.3 0.0 3.1 1 1 2 3 3 3 3 XFP N-terminal domain XFP_C PF09363.5 EEQ76387.1 - 5.8e-66 221.7 0.0 8.9e-66 221.1 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 EEQ76387.1 - 3.4e-49 166.8 0.0 8.8e-41 139.4 0.0 2.3 1 1 1 2 2 2 2 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.16 EEQ76387.1 - 0.012 15.1 0.2 0.03 13.8 0.2 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Acetate_kinase PF00871.12 EEQ76388.1 - 5.5e-35 120.6 0.1 9.5e-22 77.0 0.0 3.0 1 1 2 3 3 3 3 Acetokinase family CP2 PF04516.10 EEQ76394.1 - 8.7e-60 201.7 0.0 1.6e-59 200.8 0.0 1.4 1 0 0 1 1 1 1 CP2 transcription factor Pkinase PF00069.20 EEQ76395.1 - 3.3e-25 88.7 0.0 4.9e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ76395.1 - 3.5e-07 29.5 0.0 5.1e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ76395.1 - 0.0021 17.0 0.0 0.0032 16.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RICTOR_M PF14666.1 EEQ76395.1 - 0.15 11.0 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain Fungal_trans PF04082.13 EEQ76396.1 - 9.5e-28 96.7 0.1 6.9e-27 93.9 0.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ76396.1 - 4.5e-08 32.8 8.0 8.3e-08 32.0 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 EEQ76397.1 - 4e-06 26.4 1.2 1.5e-05 24.6 0.1 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EEQ76397.1 - 0.0013 18.3 0.0 0.0047 16.5 0.0 2.0 1 0 0 1 1 1 1 F-box domain DUF1981 PF09324.5 EEQ76397.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) Ras PF00071.17 EEQ76398.1 - 1.9e-55 186.6 0.0 3.3e-55 185.9 0.0 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EEQ76398.1 - 5.2e-20 72.1 0.0 7.7e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEQ76398.1 - 1.1e-13 50.7 0.0 1.7e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEQ76398.1 - 3e-06 26.5 0.0 5.2e-06 25.7 0.0 1.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EEQ76398.1 - 1.5e-05 24.5 0.0 3.6e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEQ76398.1 - 0.00034 20.5 0.0 0.00053 19.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EEQ76398.1 - 0.013 15.5 0.0 0.031 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain OATP PF03137.15 EEQ76399.1 - 0.0053 14.8 2.2 0.045 11.8 0.0 2.1 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family AAA_16 PF13191.1 EEQ76400.1 - 1.9e-05 24.7 0.4 0.00073 19.5 0.3 2.6 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EEQ76400.1 - 0.00058 19.6 0.0 0.0015 18.2 0.0 1.7 1 0 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 EEQ76400.1 - 0.00064 19.1 0.0 0.0028 17.0 0.0 2.0 2 1 1 3 3 3 1 AAA domain AAA_29 PF13555.1 EEQ76400.1 - 0.049 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP-synt_ab PF00006.20 EEQ76400.1 - 0.066 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.1 EEQ76400.1 - 0.081 13.0 0.1 0.21 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EEQ76400.1 - 0.089 11.9 0.1 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA PF00004.24 EEQ76400.1 - 0.095 12.8 0.0 0.54 10.4 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CLU PF13236.1 EEQ76401.1 - 1.6e-79 266.4 0.0 2.6e-79 265.7 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EEQ76401.1 - 3.9e-54 183.1 0.0 1.1e-53 181.6 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 EEQ76401.1 - 3.3e-27 94.2 11.3 5e-10 39.1 0.0 4.1 2 1 3 5 5 5 4 Tetratricopeptide repeat CLU_N PF15044.1 EEQ76401.1 - 1.4e-25 89.2 0.7 1.4e-25 89.2 0.5 1.8 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.1 EEQ76401.1 - 2.6e-14 52.5 0.0 0.0011 18.7 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ76401.1 - 0.00012 21.7 0.5 0.37 10.8 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ76401.1 - 0.00027 20.5 0.7 0.96 9.1 0.0 3.6 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.1 EEQ76401.1 - 0.035 14.2 1.6 92 3.6 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ76401.1 - 0.16 11.8 0.9 1.2 9.1 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat EnY2 PF10163.4 EEQ76401.1 - 0.17 11.8 5.0 0.65 9.9 0.1 3.4 4 0 0 4 4 4 0 Transcription factor e(y)2 BCS1_N PF08740.6 EEQ76404.1 - 2.5e-51 173.9 0.7 3.3e-51 173.5 0.5 1.1 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EEQ76404.1 - 5.4e-17 62.2 0.0 9.6e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEQ76404.1 - 3.6e-05 24.5 0.0 8.2e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEQ76404.1 - 6.9e-05 23.1 0.0 0.0025 18.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEQ76404.1 - 0.00015 21.8 0.2 0.0015 18.5 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EEQ76404.1 - 0.00031 20.6 0.0 0.001 18.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EEQ76404.1 - 0.0026 17.9 0.0 0.01 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EEQ76404.1 - 0.0034 16.8 0.0 0.016 14.7 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EEQ76404.1 - 0.0078 16.5 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 ABC transporter DUF815 PF05673.8 EEQ76404.1 - 0.011 14.6 0.0 0.02 13.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 EEQ76404.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EEQ76404.1 - 0.024 13.7 0.0 0.053 12.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 EEQ76404.1 - 0.028 14.1 0.0 0.075 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.1 EEQ76404.1 - 0.049 13.5 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EEQ76404.1 - 0.05 13.7 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 EEQ76404.1 - 0.067 12.9 0.0 0.3 10.8 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain Viral_helicase1 PF01443.13 EEQ76404.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF258 PF03193.11 EEQ76404.1 - 0.13 11.4 0.0 0.55 9.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 KaiC PF06745.8 EEQ76404.1 - 0.15 11.1 0.0 0.78 8.8 0.0 1.9 1 1 1 2 2 2 0 KaiC Miro PF08477.8 EEQ76404.1 - 0.16 12.4 0.0 0.37 11.3 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein DNA_ligase_A_M PF01068.16 EEQ76405.1 - 0.06 12.7 0.0 0.1 11.9 0.0 1.4 1 1 0 1 1 1 0 ATP dependent DNA ligase domain Cpn60_TCP1 PF00118.19 EEQ76406.1 - 2.1e-159 531.2 0.4 2.4e-159 531.0 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1168 PF06658.7 EEQ76407.1 - 9e-43 145.1 13.7 1.3e-42 144.7 9.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Peptidase_S49_N PF08496.5 EEQ76407.1 - 0.65 9.7 7.5 0.97 9.2 5.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1517 PF07466.6 EEQ76407.1 - 0.99 8.3 3.3 1.5 7.7 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) RNase_H2-Ydr279 PF09468.5 EEQ76407.1 - 1.9 7.6 7.7 2.9 7.0 5.4 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) U79_P34 PF03064.11 EEQ76407.1 - 8.6 5.8 11.7 13 5.2 8.1 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 zf-PARP PF00645.13 EEQ76408.1 - 6.8e-21 74.3 1.8 1.2e-20 73.5 1.3 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region AAA_12 PF13087.1 EEQ76409.1 - 5.9e-36 123.7 0.0 9.4e-36 123.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEQ76409.1 - 2.7e-23 82.8 0.1 9.7e-23 80.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ76409.1 - 4.4e-07 29.5 0.1 1.2e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EEQ76409.1 - 3.8e-06 26.6 0.4 7.1e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EEQ76409.1 - 3.9e-05 22.8 0.1 0.00064 18.7 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 EEQ76409.1 - 0.0021 17.6 0.0 0.6 9.5 0.0 3.5 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EEQ76409.1 - 0.0025 17.8 0.0 0.009 16.0 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.1 EEQ76409.1 - 0.014 15.5 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF4042 PF13251.1 EEQ76409.1 - 0.025 14.0 0.2 0.34 10.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) PhoH PF02562.11 EEQ76409.1 - 0.031 13.5 0.0 0.075 12.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.24 EEQ76409.1 - 0.036 14.2 0.2 0.13 12.5 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EEQ76409.1 - 0.067 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein UvrD-helicase PF00580.16 EEQ76409.1 - 0.19 11.0 0.1 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain ResIII PF04851.10 EEQ76409.1 - 0.36 10.6 0.0 0.71 9.6 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Kinesin PF00225.18 EEQ76410.1 - 6.5e-56 189.4 0.0 1.2e-55 188.5 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain bZIP_2 PF07716.10 EEQ76410.1 - 0.016 15.0 0.3 0.016 15.0 0.2 1.9 2 0 0 2 2 2 0 Basic region leucine zipper AAA_33 PF13671.1 EEQ76410.1 - 0.081 12.7 1.8 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain TPR_11 PF13414.1 EEQ76411.1 - 0.089 12.4 7.6 1.9 8.1 0.1 4.6 5 1 0 5 5 5 0 TPR repeat ChAPs PF09295.5 EEQ76412.1 - 2.1e-155 517.3 0.0 2.7e-155 517.0 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 EEQ76412.1 - 4e-07 29.5 0.3 0.019 14.6 0.0 2.7 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.1 EEQ76412.1 - 4e-05 23.1 0.1 0.88 9.5 0.0 4.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ76412.1 - 5e-05 22.7 0.2 1.2 8.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ76412.1 - 5.1e-05 22.8 3.3 0.042 13.7 0.1 4.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ76412.1 - 0.00016 21.9 0.5 0.12 12.7 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ76412.1 - 0.00033 21.0 9.7 1.6 9.6 0.2 5.6 4 2 3 7 7 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EEQ76412.1 - 0.0044 17.1 1.8 0.92 9.6 0.0 3.4 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EEQ76412.1 - 0.0052 16.5 0.1 2.3 8.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ76412.1 - 0.049 14.3 0.1 64 4.4 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat YejG PF13989.1 EEQ76412.1 - 0.1 12.6 0.3 0.45 10.5 0.0 2.2 3 0 0 3 3 3 0 YejG-like protein TPR_12 PF13424.1 EEQ76412.1 - 0.23 11.4 7.2 13 5.8 0.1 4.5 3 2 3 6 6 6 0 Tetratricopeptide repeat Utp14 PF04615.8 EEQ76413.1 - 3.5 5.6 25.1 3.8 5.5 17.4 1.0 1 0 0 1 1 1 0 Utp14 protein CENP-T PF15511.1 EEQ76413.1 - 4.7 6.3 31.9 6.8 5.8 22.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T ERCC4 PF02732.10 EEQ76414.1 - 7.6e-32 110.0 0.0 1.6e-31 108.9 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 EEQ76414.1 - 0.003 17.7 0.0 0.011 15.9 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain PAP2 PF01569.16 EEQ76415.1 - 0.21 11.2 0.8 0.19 11.3 0.5 1.3 1 1 0 1 1 1 0 PAP2 superfamily E1-E2_ATPase PF00122.15 EEQ76416.1 - 1.7e-54 184.2 0.0 1.1e-52 178.3 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EEQ76416.1 - 1.8e-35 123.2 1.4 3.3e-35 122.4 0.9 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EEQ76416.1 - 2.8e-32 110.6 5.5 2.1e-10 40.5 0.0 4.7 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 EEQ76416.1 - 9.4e-19 68.3 0.0 2e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEQ76416.1 - 2e-05 24.2 1.5 0.00064 19.3 0.3 2.4 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase GFA PF04828.9 EEQ76416.1 - 0.58 10.1 2.5 20 5.1 0.0 3.7 5 0 0 5 5 5 0 Glutathione-dependent formaldehyde-activating enzyme TFIIB PF00382.14 EEQ76417.1 - 1.8e-30 104.5 1.8 5.9e-16 58.0 0.1 2.5 1 1 1 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EEQ76417.1 - 2.4e-26 91.7 0.7 6.7e-26 90.3 0.0 2.2 2 0 0 2 2 2 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 EEQ76417.1 - 7.8e-06 25.4 0.1 0.041 13.4 0.0 2.3 1 1 1 2 2 2 2 Cyclin, N-terminal domain TF_Zn_Ribbon PF08271.7 EEQ76417.1 - 0.00038 19.7 2.6 0.00082 18.6 1.8 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding RRN7 PF11781.3 EEQ76417.1 - 0.15 11.5 0.1 0.29 10.6 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 IBR PF01485.16 EEQ76417.1 - 0.18 11.7 0.9 0.39 10.6 0.6 1.5 1 0 0 1 1 1 0 IBR domain TPT PF03151.11 EEQ76419.1 - 1.5e-27 96.1 10.3 1.5e-27 96.1 7.2 2.6 3 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EEQ76419.1 - 7.4e-05 21.8 20.7 0.00066 18.6 14.3 2.0 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EEQ76419.1 - 0.081 12.9 32.8 0.062 13.3 7.1 2.7 3 0 0 3 3 3 0 EamA-like transporter family NAD_binding_8 PF13450.1 EEQ76421.1 - 6.6e-09 35.6 0.0 1.4e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EEQ76421.1 - 6.1e-06 25.5 0.0 0.00015 21.0 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EEQ76421.1 - 4.3e-05 23.6 0.9 0.00011 22.3 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEQ76421.1 - 0.0055 16.6 0.0 0.027 14.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EEQ76421.1 - 0.0072 15.4 0.1 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EEQ76421.1 - 0.031 13.3 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 EEQ76421.1 - 0.076 11.9 0.1 0.21 10.4 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EEQ76421.1 - 0.1 12.4 0.2 1 9.0 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EEQ76421.1 - 0.11 10.9 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.2 EEQ76421.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 EEQ76421.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Pkinase PF00069.20 EEQ76423.1 - 7.5e-66 221.9 0.0 1e-65 221.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ76423.1 - 6.9e-33 113.8 0.0 2.3e-32 112.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEQ76423.1 - 5.5e-05 22.3 0.0 9.3e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEQ76423.1 - 0.00013 21.0 0.0 0.00039 19.4 0.0 1.9 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EEQ76423.1 - 0.0056 16.4 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4171 PF13775.1 EEQ76423.1 - 3.1 8.0 9.8 0.097 12.8 2.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4171) DUF3439 PF11921.3 EEQ76424.1 - 0.41 10.4 12.3 2.1 8.1 5.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 EEQ76424.1 - 0.64 7.6 3.1 0.86 7.2 2.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Seryl_tRNA_N PF02403.17 EEQ76425.1 - 6.4e-07 29.3 4.3 1.8e-05 24.7 3.0 2.2 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EEQ76425.1 - 0.00044 19.9 1.9 0.00061 19.4 1.3 1.2 1 0 0 1 1 1 1 IncA protein AAA_13 PF13166.1 EEQ76425.1 - 0.0035 15.8 0.5 0.0047 15.4 0.3 1.1 1 0 0 1 1 1 1 AAA domain FUSC PF04632.7 EEQ76425.1 - 0.038 12.4 3.1 0.055 11.8 2.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family tRNA-synt_2b PF00587.20 EEQ76425.1 - 0.056 13.0 0.0 0.29 10.7 0.0 1.9 1 1 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) TMCO5 PF14992.1 EEQ76425.1 - 0.14 11.2 4.7 0.21 10.7 3.3 1.1 1 0 0 1 1 1 0 TMCO5 family Spc7 PF08317.6 EEQ76425.1 - 0.33 9.5 6.4 0.46 9.0 4.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2968 PF11180.3 EEQ76425.1 - 0.49 9.7 9.7 2.3 7.5 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) APG6 PF04111.7 EEQ76425.1 - 0.76 8.7 7.7 1.1 8.2 5.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 EEQ76425.1 - 0.8 8.0 4.8 1.2 7.4 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DivIC PF04977.10 EEQ76425.1 - 2.2 7.8 5.5 14 5.2 0.3 2.5 2 0 0 2 2 2 0 Septum formation initiator ATG16 PF08614.6 EEQ76425.1 - 2.6 7.7 12.2 2.9 7.6 6.9 2.0 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Mnd1 PF03962.10 EEQ76425.1 - 3.4 7.3 8.0 5.2 6.6 5.6 1.2 1 0 0 1 1 1 0 Mnd1 family ADIP PF11559.3 EEQ76425.1 - 5.5 6.8 11.6 1.9 8.3 0.3 2.2 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3999 PF13163.1 EEQ76429.1 - 0.00069 18.6 0.3 0.00091 18.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3999) Cytochrom_B561 PF03188.11 EEQ76429.1 - 0.0021 17.9 6.0 0.046 13.5 0.1 2.9 1 1 2 3 3 3 2 Eukaryotic cytochrome b561 Allantoicase PF03561.10 EEQ76430.1 - 6.2e-87 288.7 0.0 8.8e-47 158.3 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat HATPase_c PF02518.21 EEQ76431.1 - 1.3e-28 98.9 0.1 3.9e-28 97.3 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EEQ76431.1 - 2.3e-21 75.8 0.5 6e-21 74.5 0.1 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EEQ76431.1 - 2.9e-19 68.7 0.0 1e-18 67.0 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.1 EEQ76431.1 - 3.5e-13 50.2 0.1 7.7e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 EEQ76431.1 - 6.6e-10 39.3 0.0 1.6e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 GAF domain AAA_16 PF13191.1 EEQ76431.1 - 1.8e-09 37.8 1.2 1.4e-08 34.9 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain GAF_3 PF13492.1 EEQ76431.1 - 1.1e-07 32.0 0.0 2.7e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 EEQ76431.1 - 3.3e-07 29.7 0.0 1.4e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain NACHT PF05729.7 EEQ76431.1 - 0.00079 19.1 0.1 0.013 15.1 0.1 2.5 1 1 0 1 1 1 1 NACHT domain ArgK PF03308.11 EEQ76431.1 - 0.0014 17.4 0.0 0.0027 16.5 0.0 1.4 1 0 0 1 1 1 1 ArgK protein HATPase_c_3 PF13589.1 EEQ76431.1 - 0.002 17.8 0.0 0.0048 16.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_2 PF07719.12 EEQ76431.1 - 0.017 14.9 12.1 0.23 11.4 0.1 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ76431.1 - 3.6 7.5 9.3 1.9 8.4 0.2 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ76431.1 - 6.1 7.5 7.8 3.1 8.4 1.7 3.6 4 0 0 4 4 2 0 Tetratricopeptide repeat DUF605 PF04652.11 EEQ76434.1 - 5.5 6.2 7.6 6.1 6.1 5.3 1.1 1 0 0 1 1 1 0 Vta1 like Dicty_REP PF05086.7 EEQ76434.1 - 8.5 3.9 6.9 8.1 4.0 4.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HATPase_c PF02518.21 EEQ76435.1 - 3.3e-22 78.2 0.5 9.1e-22 76.8 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EEQ76435.1 - 1.9e-21 76.1 0.1 1.5e-20 73.3 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EEQ76435.1 - 1e-17 63.8 0.5 3.1e-17 62.3 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 EEQ76435.1 - 8e-11 42.2 0.0 7.1e-08 32.7 0.0 3.6 3 1 0 3 3 3 1 PAS domain PAS_3 PF08447.6 EEQ76435.1 - 2.7e-10 40.2 1.0 0.016 15.3 0.0 3.7 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.5 EEQ76435.1 - 0.0001 22.2 0.3 0.00041 20.3 0.0 2.3 3 0 0 3 3 3 1 PAS fold PAS PF00989.19 EEQ76435.1 - 0.0012 18.6 0.0 3 7.6 0.0 3.0 2 0 0 2 2 2 2 PAS fold HATPase_c_2 PF13581.1 EEQ76435.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain KxDL PF10241.4 EEQ76437.1 - 7.5e-32 109.0 2.0 9.4e-32 108.7 1.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein ATP-synt_B PF00430.13 EEQ76437.1 - 0.36 10.6 5.0 0.5 10.1 3.5 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Zds_C PF08632.5 EEQ76439.1 - 0.023 14.0 0.2 0.05 12.9 0.2 1.5 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term AAA PF00004.24 EEQ76440.1 - 5.2e-54 181.9 0.0 4.5e-39 133.6 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EEQ76440.1 - 2.9e-15 55.9 0.0 6.4e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_22 PF13401.1 EEQ76440.1 - 1.6e-10 41.2 0.1 0.00039 20.5 0.0 4.1 2 2 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 EEQ76440.1 - 6.7e-10 38.4 0.1 7.1e-09 35.1 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_17 PF13207.1 EEQ76440.1 - 7.7e-09 36.4 0.1 0.0025 18.6 0.1 2.8 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EEQ76440.1 - 7.8e-09 35.7 0.0 0.0014 18.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.1 EEQ76440.1 - 9.5e-09 35.2 0.0 0.0012 18.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EEQ76440.1 - 3.3e-08 33.1 1.9 0.005 16.5 0.0 3.0 3 0 0 3 3 3 2 Part of AAA domain AAA_5 PF07728.9 EEQ76440.1 - 3.5e-08 33.2 0.2 0.0016 18.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EEQ76440.1 - 8.5e-08 31.3 0.0 0.0093 14.7 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_2 PF07724.9 EEQ76440.1 - 9.8e-08 32.0 0.0 4e-05 23.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EEQ76440.1 - 1.1e-07 32.1 0.0 0.0049 17.1 0.0 3.3 4 0 0 4 4 2 2 AAA domain RNA_helicase PF00910.17 EEQ76440.1 - 2.3e-07 30.9 0.0 0.036 14.2 0.0 2.6 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.7 EEQ76440.1 - 2.6e-07 29.9 0.1 0.02 13.9 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EEQ76440.1 - 3.1e-07 29.7 0.1 0.0049 16.0 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EEQ76440.1 - 1.1e-06 28.6 0.0 0.036 13.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EEQ76440.1 - 3.5e-06 26.5 0.1 0.041 13.2 0.0 2.7 3 0 0 3 3 3 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 EEQ76440.1 - 1.9e-05 23.8 0.0 0.077 12.0 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.7 EEQ76440.1 - 2.9e-05 23.7 0.2 0.032 13.8 0.0 3.0 3 0 0 3 3 2 1 NACHT domain AAA_24 PF13479.1 EEQ76440.1 - 3e-05 23.6 0.2 0.12 11.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEQ76440.1 - 5.4e-05 22.6 1.5 0.68 9.2 0.0 3.3 2 2 1 3 3 3 2 AAA domain NB-ARC PF00931.17 EEQ76440.1 - 9.4e-05 21.3 0.0 0.21 10.3 0.0 2.7 3 0 0 3 3 2 2 NB-ARC domain AAA_28 PF13521.1 EEQ76440.1 - 0.00016 21.6 0.0 0.3 11.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 EEQ76440.1 - 0.00017 20.7 0.3 0.036 13.1 0.1 2.4 2 0 0 2 2 2 1 KaiC ABC_tran PF00005.22 EEQ76440.1 - 0.00025 21.3 0.1 0.039 14.2 0.1 2.5 2 0 0 2 2 2 1 ABC transporter PhoH PF02562.11 EEQ76440.1 - 0.00031 20.0 0.0 0.58 9.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 EEQ76440.1 - 0.00035 20.1 0.0 0.4 10.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EEQ76440.1 - 0.00064 19.2 0.0 0.6 9.5 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF2075 PF09848.4 EEQ76440.1 - 0.00079 18.5 0.0 0.33 9.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 EEQ76440.1 - 0.0013 18.4 0.2 4.3 6.9 0.2 3.3 2 1 1 3 3 3 0 Archaeal ATPase AAA_11 PF13086.1 EEQ76440.1 - 0.0015 18.1 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain UPF0079 PF02367.12 EEQ76440.1 - 0.0036 16.9 0.1 1 9.0 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 KTI12 PF08433.5 EEQ76440.1 - 0.0038 16.4 0.0 0.58 9.3 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Parvo_NS1 PF01057.12 EEQ76440.1 - 0.0055 15.6 0.0 0.41 9.4 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 EEQ76440.1 - 0.0084 15.7 0.0 0.93 9.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EEQ76440.1 - 0.026 14.5 0.0 8.7 6.3 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain DEAD PF00270.24 EEQ76440.1 - 0.029 13.8 0.3 22 4.4 0.0 3.9 2 2 1 4 4 4 0 DEAD/DEAH box helicase SRP54 PF00448.17 EEQ76440.1 - 0.046 13.1 0.1 4.5 6.6 0.0 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain ResIII PF04851.10 EEQ76440.1 - 0.051 13.4 0.1 13 5.5 0.0 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit T2SE PF00437.15 EEQ76440.1 - 0.057 12.3 0.0 6.5 5.5 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.10 EEQ76440.1 - 0.065 12.9 0.0 14 5.3 0.0 2.5 2 0 0 2 2 2 0 NTPase cobW PF02492.14 EEQ76440.1 - 0.073 12.5 0.0 4.2 6.7 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.9 EEQ76440.1 - 0.075 12.0 0.0 5.4 5.9 0.0 2.8 2 1 0 2 2 2 0 KAP family P-loop domain ATP-synt_ab PF00006.20 EEQ76440.1 - 0.36 10.2 2.2 12 5.3 0.0 3.3 3 1 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Cir_N PF10197.4 EEQ76441.1 - 8.9e-05 22.4 1.2 8.9e-05 22.4 0.8 4.8 5 0 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR Methyltransf_31 PF13847.1 EEQ76442.1 - 7.3e-11 41.8 0.0 1.2e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ76442.1 - 1.3e-08 35.4 0.0 3.3e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EEQ76442.1 - 5.4e-08 32.2 0.1 9.2e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EEQ76442.1 - 2.6e-07 31.0 0.0 5.4e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ76442.1 - 5.1e-06 26.5 0.0 9.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ76442.1 - 2.9e-05 23.8 0.0 7.6e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ76442.1 - 3.3e-05 23.3 0.0 5.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EEQ76442.1 - 0.00024 21.3 0.0 0.00053 20.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EEQ76442.1 - 0.00078 18.2 0.0 0.0013 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PRMT5 PF05185.11 EEQ76442.1 - 0.0042 16.0 0.0 0.0065 15.4 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.7 EEQ76442.1 - 0.014 15.8 0.0 0.028 14.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 EEQ76442.1 - 0.035 13.6 0.1 0.067 12.7 0.1 1.3 1 0 0 1 1 1 0 Met-10+ like-protein CMAS PF02353.15 EEQ76442.1 - 0.04 12.9 0.1 0.19 10.7 0.0 2.0 3 0 0 3 3 3 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EEQ76442.1 - 0.046 13.7 0.1 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EEQ76442.1 - 0.095 11.7 0.1 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TehB PF03848.9 EEQ76442.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB GrpE PF01025.14 EEQ76442.1 - 0.16 11.4 0.5 0.36 10.3 0.3 1.5 1 0 0 1 1 1 0 GrpE Mo25 PF08569.6 EEQ76443.1 - 9.1e-130 432.5 0.1 1e-129 432.3 0.1 1.0 1 0 0 1 1 1 1 Mo25-like RabGAP-TBC PF00566.13 EEQ76444.1 - 2.9e-35 121.7 0.0 4.2e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DPCD PF14913.1 EEQ76444.1 - 0.095 11.8 0.2 0.2 10.7 0.1 1.5 1 0 0 1 1 1 0 DPCD protein family Ank_2 PF12796.2 EEQ76451.1 - 3.5e-19 68.9 0.0 1.8e-18 66.6 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) DIL PF01843.14 EEQ76451.1 - 4.6e-17 61.8 3.8 9.3e-12 44.7 0.1 2.7 3 0 0 3 3 3 2 DIL domain Ank PF00023.25 EEQ76451.1 - 6.5e-16 57.2 0.0 6.5e-07 28.8 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EEQ76451.1 - 2.8e-15 55.9 0.0 1.3e-07 31.6 0.0 3.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ76451.1 - 6.4e-10 38.2 0.2 0.0086 16.2 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EEQ76451.1 - 6.6e-10 39.2 0.0 5.7e-05 23.5 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) MgtE PF01769.11 EEQ76452.1 - 0.0053 17.0 0.0 0.0064 16.7 0.0 1.1 1 0 0 1 1 1 1 Divalent cation transporter RasGEF PF00617.14 EEQ76454.1 - 4.9e-44 150.3 0.5 4.9e-44 150.3 0.4 2.0 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EEQ76454.1 - 6.2e-12 45.5 0.8 1.7e-11 44.1 0.4 1.9 1 1 0 1 1 1 1 RasGEF N-terminal motif IF-2B PF01008.12 EEQ76454.1 - 0.079 11.9 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family WTX PF09422.5 EEQ76456.1 - 0.031 13.2 0.4 0.036 13.0 0.3 1.1 1 0 0 1 1 1 0 WTX protein TaqI_C PF12950.2 EEQ76456.1 - 0.071 12.8 2.1 0.1 12.3 1.5 1.2 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain DUF3540 PF12059.3 EEQ76456.1 - 0.14 11.7 2.8 0.16 11.5 1.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3540) Atg14 PF10186.4 EEQ76456.1 - 1.6 7.5 7.3 2 7.2 5.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ATP-synt_E PF05680.7 EEQ76456.1 - 9 6.3 9.7 8.3 6.4 5.8 1.5 1 1 0 1 1 1 0 ATP synthase E chain Arginosuc_synth PF00764.14 EEQ76458.1 - 8e-149 495.8 0.0 9.3e-149 495.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 EEQ76458.1 - 0.00072 19.1 0.0 0.00096 18.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EEQ76458.1 - 0.023 13.9 0.0 0.063 12.5 0.0 1.7 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Peptidase_M13_N PF05649.8 EEQ76459.1 - 1.3e-72 245.0 0.0 1.9e-72 244.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EEQ76459.1 - 4e-59 199.2 0.0 6.6e-59 198.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 ORF6C PF10552.4 EEQ76459.1 - 0.073 12.8 0.2 5.8 6.6 0.1 2.6 2 0 0 2 2 2 0 ORF6C domain MAD PF05557.8 EEQ76461.1 - 5.6e-51 173.5 77.3 2.8e-41 141.4 53.2 3.5 2 1 0 2 2 2 2 Mitotic checkpoint protein FliD_C PF07195.7 EEQ76461.1 - 9.4e-05 21.8 7.0 9.4e-05 21.8 4.9 3.6 2 2 0 3 3 3 1 Flagellar hook-associated protein 2 C-terminus Y_phosphatase3 PF13350.1 EEQ76461.1 - 0.15 12.2 21.5 0.27 11.4 3.5 3.6 3 0 0 3 3 3 0 Tyrosine phosphatase family Reo_sigmaC PF04582.7 EEQ76461.1 - 0.55 9.3 33.0 0.03 13.5 5.9 4.6 2 1 4 6 6 6 0 Reovirus sigma C capsid protein Pkinase PF00069.20 EEQ76462.1 - 3.7e-46 157.3 0.0 5.3e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ76462.1 - 3.5e-18 65.6 0.0 5.4e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ76462.1 - 0.00027 20.7 0.5 0.024 14.3 0.1 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EEQ76462.1 - 0.00046 19.2 0.0 0.00076 18.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EEQ76462.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF2577 PF10844.3 EEQ76463.1 - 1.5 8.8 6.1 0.29 11.1 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2577) muHD PF10291.4 EEQ76464.1 - 8.8e-83 277.4 0.0 1.4e-82 276.7 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 EEQ76464.1 - 3.3e-09 36.8 1.0 1e-08 35.2 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Laminin_II PF06009.7 EEQ76464.1 - 0.0097 15.6 2.8 0.023 14.4 1.9 1.6 1 0 0 1 1 1 1 Laminin Domain II Spc7 PF08317.6 EEQ76464.1 - 0.022 13.4 2.5 0.036 12.7 1.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Muted PF14942.1 EEQ76464.1 - 0.023 14.5 3.4 0.051 13.4 2.4 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF4164 PF13747.1 EEQ76464.1 - 0.026 14.6 1.5 0.081 13.0 1.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Fib_alpha PF08702.5 EEQ76464.1 - 0.031 14.3 1.5 0.064 13.3 1.0 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DDRGK PF09756.4 EEQ76464.1 - 0.3 10.4 2.6 0.6 9.4 1.8 1.4 1 0 0 1 1 1 0 DDRGK domain Mnd1 PF03962.10 EEQ76464.1 - 8.9 5.9 12.7 6.1 6.4 6.1 2.4 2 1 0 2 2 2 0 Mnd1 family SH3_9 PF14604.1 EEQ76467.1 - 1.8e-08 33.8 0.0 3.1e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEQ76467.1 - 1.3e-05 24.4 0.0 2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EEQ76467.1 - 3.1e-05 23.3 0.0 5.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF2668 PF10873.3 EEQ76467.1 - 0.63 10.1 0.0 0.63 10.1 0.0 4.4 6 1 1 7 7 7 0 Protein of unknown function (DUF2668) OPT PF03169.10 EEQ76468.1 - 4.4e-168 560.5 9.9 5.3e-168 560.2 6.9 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Rav1p_C PF12234.3 EEQ76469.1 - 3e-280 930.8 0.1 3.7e-280 930.5 0.1 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 EEQ76469.1 - 1.3e-09 37.5 1.9 0.045 13.6 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat Sfi1 PF08457.5 EEQ76470.1 - 2.4e-159 531.4 88.4 2e-158 528.3 54.0 2.1 1 1 1 2 2 2 2 Sfi1 spindle body protein CHCH PF06747.8 EEQ76471.1 - 0.0095 15.8 3.6 0.23 11.4 0.4 2.1 2 0 0 2 2 2 2 CHCH domain NDUF_B7 PF05676.8 EEQ76471.1 - 0.017 14.5 2.1 2.2 7.7 0.1 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EEQ76471.1 - 0.031 14.0 2.1 0.031 14.0 1.5 1.6 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like SCRL PF06876.7 EEQ76471.1 - 0.055 13.4 0.4 0.069 13.1 0.3 1.1 1 0 0 1 1 1 0 Plant self-incompatibility response (SCRL) protein UCR_hinge PF02320.11 EEQ76471.1 - 0.23 11.4 2.2 0.36 10.8 1.5 1.4 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein DUF2800 PF10926.3 EEQ76471.1 - 0.28 10.2 1.5 0.3 10.1 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) tRNA-synt_1 PF00133.17 EEQ76472.1 - 5e-218 724.9 0.0 7.8e-218 724.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EEQ76472.1 - 1.2e-24 86.7 0.0 3.4e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EEQ76472.1 - 8.8e-17 60.8 0.0 2.3e-07 29.8 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) Uso1_p115_head PF04869.9 EEQ76473.1 - 5.4e-117 390.0 0.0 1.7e-116 388.3 0.0 1.9 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EEQ76473.1 - 1.1e-07 31.8 26.1 1.1e-07 31.8 18.1 3.4 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3584 PF12128.3 EEQ76473.1 - 7.8e-05 20.2 47.9 0.00012 19.6 33.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Tropomyosin PF00261.15 EEQ76473.1 - 0.59 9.1 53.7 0.16 10.9 34.7 2.1 1 1 0 1 1 1 0 Tropomyosin AAA_13 PF13166.1 EEQ76473.1 - 4 5.7 36.2 0.74 8.1 20.3 1.9 1 1 1 2 2 2 0 AAA domain Filament PF00038.16 EEQ76473.1 - 6.1 6.2 45.9 2.7 7.4 29.1 2.1 1 1 0 1 1 1 0 Intermediate filament protein Lebercilin PF15619.1 EEQ76473.1 - 7.3 5.9 50.5 0.046 13.1 21.9 3.0 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease zf-C4H2 PF10146.4 EEQ76473.1 - 8.2 6.3 31.2 1.8 8.5 18.2 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein Baculo_p24 PF05073.7 EEQ76473.1 - 8.4 5.9 15.4 0.49 9.9 1.6 2.5 1 1 1 2 2 2 0 Baculovirus P24 capsid protein XRN_N PF03159.13 EEQ76474.1 - 7.8e-109 362.6 0.3 1.5e-107 358.4 0.0 2.1 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 EEQ76474.1 - 0.0085 15.9 2.5 0.0085 15.9 1.7 2.1 2 0 0 2 2 2 1 Zinc knuckle EPSP_synthase PF00275.15 EEQ76475.1 - 5.5e-125 417.0 0.0 8.4e-125 416.4 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EEQ76475.1 - 6.9e-99 329.9 0.0 1.2e-98 329.2 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EEQ76475.1 - 4.1e-63 213.0 0.0 7.2e-63 212.2 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EEQ76475.1 - 9e-40 136.1 0.0 5.2e-39 133.6 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EEQ76475.1 - 9.7e-24 83.2 0.0 2.4e-23 81.9 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EEQ76475.1 - 1.1e-08 35.1 0.0 3.1e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EEQ76475.1 - 2.5e-07 30.2 0.0 7.3e-07 28.7 0.0 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EEQ76475.1 - 0.00042 21.1 0.0 0.0028 18.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Exo5 PF09810.4 EEQ76476.1 - 2e-119 398.5 0.0 2.5e-119 398.2 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 EEQ76476.1 - 7.8e-05 22.1 0.2 0.24 10.7 0.0 2.7 2 1 0 2 2 2 2 PD-(D/E)XK nuclease superfamily Mpv17_PMP22 PF04117.7 EEQ76477.1 - 2.9e-17 62.0 0.8 2.9e-17 62.0 0.6 1.9 1 1 1 2 2 2 1 Mpv17 / PMP22 family Histone PF00125.19 EEQ76478.1 - 1.1e-31 108.7 0.4 1.8e-31 108.0 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EEQ76478.1 - 2.9e-06 27.3 0.0 4.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EEQ76478.1 - 0.0037 17.2 0.3 0.0074 16.3 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EEQ76478.1 - 0.041 13.6 0.1 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 EEQ76479.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EEQ76479.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EEQ76479.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EEQ76479.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EEQ76479.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EEQ76479.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Serglycin PF04360.7 EEQ76480.1 - 7.8e-06 25.6 0.2 1.9e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Serglycin F-box PF00646.28 EEQ76480.1 - 0.0029 17.2 0.2 0.012 15.2 0.1 2.2 1 1 0 1 1 1 1 F-box domain zf-C2H2 PF00096.21 EEQ76484.1 - 3e-08 33.5 12.2 0.0004 20.5 0.9 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ76484.1 - 2.5e-06 27.3 14.9 0.0032 17.6 0.9 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-BED PF02892.10 EEQ76484.1 - 0.2 11.4 1.7 0.47 10.2 1.2 1.6 1 0 0 1 1 1 0 BED zinc finger DUF3445 PF11927.3 EEQ76485.1 - 1.3e-42 145.9 0.0 3.5e-26 92.1 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3445) Glyco_transf_22 PF03901.12 EEQ76486.1 - 5.6e-89 299.0 23.4 6.6e-89 298.7 16.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Gar1 PF04410.9 EEQ76487.1 - 2.4e-49 166.7 1.0 7.1e-49 165.2 0.7 1.9 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region PRP3 PF08572.5 EEQ76488.1 - 2.4e-70 236.4 0.9 4.6e-70 235.4 0.6 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EEQ76488.1 - 6.5e-39 132.5 0.5 1.4e-38 131.4 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RNA_pol_Rpb1_5 PF04998.12 EEQ76489.1 - 1.3e-83 280.4 0.0 3.9e-83 278.9 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EEQ76489.1 - 6.2e-63 211.6 0.1 1.5e-62 210.4 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EEQ76489.1 - 8.4e-35 119.8 0.0 2.9e-34 118.0 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EEQ76489.1 - 3.7e-25 88.9 6.8 6.8e-25 88.0 0.8 3.1 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EEQ76489.1 - 1.7e-17 63.1 0.0 6.2e-17 61.3 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF1227 PF06777.6 EEQ76490.1 - 4.2e-60 201.6 1.7 4.9e-60 201.4 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EEQ76490.1 - 1.1e-52 177.9 0.2 1.9e-52 177.1 0.1 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EEQ76490.1 - 1.3e-45 155.3 0.1 4.1e-45 153.7 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD PF00270.24 EEQ76490.1 - 0.00014 21.4 0.0 0.061 12.8 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase SNF2_N PF00176.18 EEQ76490.1 - 0.00038 19.3 0.0 0.005 15.6 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EEQ76490.1 - 0.016 15.0 0.8 0.088 12.6 0.1 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EEQ76490.1 - 0.031 14.4 0.6 2.3 8.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.1 EEQ76490.1 - 0.045 13.3 0.5 0.13 11.7 0.4 1.9 1 1 0 1 1 1 0 AAA domain Remorin_C PF03763.8 EEQ76490.1 - 0.062 12.8 2.5 0.22 11.0 1.8 1.9 1 0 0 1 1 1 0 Remorin, C-terminal region zf-RING_2 PF13639.1 EEQ76491.1 - 2.2e-08 33.7 7.2 4.7e-08 32.7 5.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EEQ76491.1 - 3.8e-07 30.1 1.7 7.8e-07 29.1 1.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 EEQ76491.1 - 3.9e-05 23.5 5.7 0.0001 22.1 4.0 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.20 EEQ76491.1 - 0.00025 20.6 9.0 0.00051 19.6 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEQ76491.1 - 0.00026 20.7 2.0 0.00051 19.8 1.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger C1_1 PF00130.17 EEQ76491.1 - 0.0056 16.3 3.1 0.0056 16.3 2.1 1.8 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.1 EEQ76491.1 - 0.013 15.4 8.4 0.033 14.2 5.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EEQ76491.1 - 0.014 15.3 7.2 0.03 14.3 5.0 1.6 1 0 0 1 1 1 0 RING-variant domain Baculo_RING PF05883.6 EEQ76491.1 - 0.16 11.8 1.2 0.44 10.3 0.8 1.7 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-C3HC4_3 PF13920.1 EEQ76491.1 - 0.4 10.4 5.6 0.73 9.5 3.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EEQ76491.1 - 0.51 10.3 6.7 1 9.3 4.6 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 EEQ76491.1 - 0.88 9.2 5.9 17 5.0 4.1 2.3 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EEQ76491.1 - 3.2 7.5 6.5 6.6 6.5 4.5 1.6 1 0 0 1 1 1 0 PHD-finger LCM PF04072.9 EEQ76492.1 - 2e-23 82.8 0.0 2.7e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase zf-C3HC4 PF00097.20 EEQ76494.1 - 8.4e-09 34.9 1.8 2e-08 33.7 1.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ76494.1 - 5.4e-08 32.5 5.1 5.4e-08 32.5 3.5 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEQ76494.1 - 7.9e-08 31.8 3.5 1.6e-07 30.8 2.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ76494.1 - 2.7e-07 30.1 3.4 5.7e-07 29.1 2.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEQ76494.1 - 7.4e-07 29.0 2.9 7.4e-07 29.0 2.0 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EEQ76494.1 - 0.00073 19.3 2.1 0.00073 19.3 1.5 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-CCCH PF00642.19 EEQ76494.1 - 0.021 14.5 2.1 0.021 14.5 1.5 3.6 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_UBOX PF13445.1 EEQ76494.1 - 0.027 14.1 1.8 0.041 13.5 0.6 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.2 EEQ76494.1 - 0.057 13.5 9.0 2.5 8.2 6.2 3.2 1 1 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 EEQ76494.1 - 0.48 10.0 4.8 1.4 8.5 0.5 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Ist1 PF03398.9 EEQ76495.1 - 2.6e-34 118.0 0.0 2.1e-16 59.7 0.4 2.2 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway Pkinase PF00069.20 EEQ76496.1 - 5e-18 65.1 0.1 3.4e-11 42.7 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ76496.1 - 0.00082 18.5 0.0 0.024 13.6 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pepsin-I3 PF06394.8 EEQ76496.1 - 0.069 12.8 0.1 6 6.6 0.0 2.5 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain MFS_1 PF07690.11 EEQ76497.1 - 5.8e-33 114.0 19.8 6.7e-33 113.8 13.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Menin PF05053.8 EEQ76497.1 - 0.19 9.8 0.1 0.28 9.3 0.1 1.1 1 0 0 1 1 1 0 Menin MFS_1 PF07690.11 EEQ76499.1 - 3.8e-10 39.0 15.4 6.8e-10 38.1 10.6 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Clat_adaptor_s PF01217.15 EEQ76501.1 - 6.9e-44 149.0 1.4 8.2e-44 148.7 1.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Acyltransferase PF01553.16 EEQ76503.1 - 2.8e-08 33.2 0.1 3.5e-07 29.7 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase TP_methylase PF00590.15 EEQ76504.1 - 6.4e-21 75.0 0.1 1.1e-20 74.2 0.1 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TFIID-18kDa PF02269.11 EEQ76505.1 - 1.4e-22 79.3 2.8 5.2e-13 48.6 0.2 3.2 2 1 1 3 3 3 2 Transcription initiation factor IID, 18kD subunit Aminotran_1_2 PF00155.16 EEQ76506.1 - 1e-59 202.3 0.0 1.2e-59 202.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EEQ76506.1 - 0.016 13.4 0.0 0.026 12.7 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Mmp37 PF09139.6 EEQ76507.1 - 1e-135 452.0 0.0 1.2e-135 451.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 RdgC PF04381.7 EEQ76507.1 - 0.06 12.2 0.0 0.099 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative exonuclease, RdgC BIR PF00653.16 EEQ76508.1 - 1.2e-25 89.7 2.4 4.5e-22 78.2 0.1 3.4 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C2H2_jaz PF12171.3 EEQ76509.1 - 8.9e-08 32.0 0.3 1.6e-07 31.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEQ76509.1 - 3e-05 24.0 0.6 5.9e-05 23.1 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EEQ76509.1 - 0.063 13.6 0.5 0.12 12.7 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EEQ76509.1 - 0.13 12.3 0.4 0.78 9.8 0.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF1266 PF06889.6 EEQ76509.1 - 1.3 8.7 11.7 0.98 9.1 4.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) EVC2_like PF12297.3 EEQ76509.1 - 6 5.3 11.9 0.79 8.2 4.3 1.9 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein F-box-like PF12937.2 EEQ76510.1 - 0.00031 20.3 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ76510.1 - 0.0058 16.2 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain U3_assoc_6 PF08640.6 EEQ76510.1 - 0.086 12.6 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 AMP-binding PF00501.23 EEQ76511.1 - 9.8e-50 169.1 0.0 1.4e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ76511.1 - 4.7e-05 24.2 0.0 0.00033 21.5 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Amidase PF01425.16 EEQ76512.1 - 5.6e-70 236.3 0.0 1e-38 133.3 0.0 2.1 1 1 1 2 2 2 2 Amidase RNA_pol_Rpb5_C PF01191.14 EEQ76515.1 - 7.8e-35 118.3 0.1 1.3e-34 117.6 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EEQ76515.1 - 4.6e-32 110.2 0.0 7.8e-32 109.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 EEQ76515.1 - 0.05 13.4 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease AAA_27 PF13514.1 EEQ76516.1 - 0.0027 15.5 47.7 0.07 10.8 12.5 3.2 2 1 1 3 3 3 3 AAA domain Occludin_ELL PF07303.8 EEQ76516.1 - 0.0091 16.7 35.2 0.14 12.9 1.6 4.4 2 1 1 4 4 4 3 Occludin homology domain AAA_13 PF13166.1 EEQ76516.1 - 0.26 9.7 45.0 0.0031 16.0 12.0 3.1 2 1 1 3 3 3 0 AAA domain EzrA PF06160.7 EEQ76516.1 - 0.29 9.2 36.0 0.11 10.6 3.4 3.1 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.4 EEQ76516.1 - 0.56 10.0 37.4 0.073 12.9 3.0 4.4 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 EEQ76516.1 - 0.61 9.0 47.9 0.014 14.4 10.4 3.2 2 1 1 3 3 3 0 Autophagy protein Apg6 MscS_porin PF12795.2 EEQ76516.1 - 0.89 8.8 47.4 3.4 6.9 10.5 3.9 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain DUF4191 PF13829.1 EEQ76516.1 - 1.2 8.2 4.9 0.45 9.5 0.2 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4191) DUF2730 PF10805.3 EEQ76516.1 - 4.1 7.2 9.5 0.71 9.6 0.8 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF2730) Cob_adeno_trans PF01923.13 EEQ76516.1 - 4.9 6.9 22.7 1.7 8.3 2.0 4.4 2 1 2 4 4 4 0 Cobalamin adenosyltransferase Reo_sigmaC PF04582.7 EEQ76516.1 - 7.8 5.5 9.8 4.2 6.4 1.1 2.5 2 1 2 4 4 4 0 Reovirus sigma C capsid protein Prominin PF05478.6 EEQ76516.1 - 8.8 3.7 16.0 0.61 7.5 7.5 1.6 2 0 0 2 2 2 0 Prominin CYSTM PF12734.2 EEQ76517.1 - 8.8 6.4 63.7 0.61 10.1 27.6 5.2 2 2 0 2 2 2 0 Cysteine-rich TM module stress tolerance Vma12 PF11712.3 EEQ76518.1 - 0.01 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Adeno_E3_CR2 PF02439.10 EEQ76518.1 - 0.93 9.0 4.1 1.7 8.2 2.9 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Glyco_hydro_35 PF01301.14 EEQ76519.1 - 4.7e-53 180.6 0.0 3.5e-45 154.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EEQ76519.1 - 9.3e-30 103.3 0.3 2.9e-24 85.4 0.1 2.5 2 0 0 2 2 2 2 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EEQ76519.1 - 1.2e-27 96.3 8.5 2.4e-22 79.3 1.2 3.6 3 1 1 4 4 4 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EEQ76519.1 - 3.7e-19 67.8 0.1 1.1e-18 66.4 0.1 1.8 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Nol1_Nop2_Fmu PF01189.12 EEQ76520.1 - 3e-34 118.7 0.0 1.3e-17 64.0 0.0 4.4 2 1 2 4 4 4 4 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EEQ76520.1 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF605 PF04652.11 EEQ76520.1 - 0.022 14.1 16.5 0.04 13.3 11.4 1.3 1 0 0 1 1 1 0 Vta1 like PLAC8 PF04749.12 EEQ76521.1 - 4.8e-27 94.5 17.7 5.7e-27 94.3 12.3 1.0 1 0 0 1 1 1 1 PLAC8 family Aldolase_II PF00596.16 EEQ76522.1 - 1.6e-46 158.2 0.0 2.1e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DEAD PF00270.24 EEQ76523.1 - 2.2e-42 144.3 0.2 3.6e-42 143.7 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ76523.1 - 1.1e-20 73.1 0.9 2.6e-20 72.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ76523.1 - 0.0039 17.0 0.0 0.0077 16.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EEQ76523.1 - 0.0084 15.4 0.3 0.018 14.3 0.0 1.6 2 0 0 2 2 2 1 SecA DEAD-like domain Ank_2 PF12796.2 EEQ76524.1 - 5.4e-64 212.5 21.1 1e-11 45.0 0.0 12.9 4 4 6 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ76524.1 - 5.3e-40 133.2 25.9 0.001 18.7 0.0 20.9 22 3 1 23 23 23 10 Ankyrin repeat Ank_4 PF13637.1 EEQ76524.1 - 6.1e-26 90.3 11.0 3.6e-05 24.1 0.0 13.6 11 2 2 13 13 13 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ76524.1 - 2.5e-24 82.9 15.6 0.022 14.9 0.0 18.9 22 0 0 22 22 22 5 Ankyrin repeat Ank_5 PF13857.1 EEQ76524.1 - 1.8e-14 53.3 17.4 0.00082 19.5 0.0 12.0 13 1 1 14 14 14 3 Ankyrin repeats (many copies) Adenylsucc_synt PF00709.16 EEQ76525.1 - 1.8e-154 514.4 0.0 2e-154 514.3 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DnaJ PF00226.26 EEQ76526.1 - 5.8e-10 38.7 1.0 1.6e-09 37.3 0.7 1.8 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.13 EEQ76527.1 - 1.4e-30 106.0 0.1 4e-30 104.5 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ76527.1 - 2.8e-08 33.5 13.5 4.6e-08 32.8 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EEQ76529.1 - 9.9e-32 110.0 27.1 5e-31 107.6 13.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ76529.1 - 2.9e-10 39.3 5.1 2.9e-10 39.3 3.5 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter GTP1_OBG PF01018.17 EEQ76531.1 - 5.8e-39 133.2 2.8 5.8e-28 97.5 1.9 2.4 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EEQ76531.1 - 5.7e-21 74.6 0.0 9.9e-21 73.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEQ76531.1 - 5.7e-08 32.1 0.1 1.3e-07 31.0 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 EEQ76531.1 - 0.0087 14.8 0.1 0.49 9.1 0.0 2.4 2 0 0 2 2 2 1 ArgK protein ABC_tran PF00005.22 EEQ76531.1 - 0.073 13.3 0.0 0.073 13.3 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.18 EEQ76531.1 - 0.15 11.8 0.1 9.8 5.9 0.0 2.4 2 0 0 2 2 2 0 Dynamin family Miro PF08477.8 EEQ76531.1 - 0.22 12.0 0.0 0.83 10.1 0.0 2.0 1 1 0 1 1 1 0 Miro-like protein Cupin_8 PF13621.1 EEQ76532.1 - 1.2e-33 116.6 0.0 2.5e-33 115.6 0.0 1.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EEQ76532.1 - 1.7e-07 30.8 0.7 0.00045 19.5 0.0 2.3 1 1 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 EEQ76532.1 - 0.0098 16.1 0.3 0.024 14.8 0.0 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EEQ76532.1 - 0.14 11.7 0.1 0.46 10.0 0.0 1.9 2 0 0 2 2 2 0 Cupin domain AHS2 PF02626.10 EEQ76533.1 - 3.6e-16 59.2 0.0 6.6e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 Biotin_lipoyl PF00364.17 EEQ76533.1 - 5.4e-15 54.7 1.7 1.3e-14 53.5 0.6 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme AHS1 PF02682.11 EEQ76533.1 - 3.4e-08 33.1 0.0 6e-07 29.1 0.0 2.6 1 1 0 1 1 1 1 Allophanate hydrolase subunit 1 Biotin_lipoyl_2 PF13533.1 EEQ76533.1 - 0.00025 20.6 0.6 0.025 14.2 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD PF00529.15 EEQ76533.1 - 0.015 14.6 0.1 0.83 8.8 0.0 2.3 2 0 0 2 2 2 0 HlyD family secretion protein LamB_YcsF PF03746.11 EEQ76535.1 - 2.1e-45 154.7 0.0 4.4e-33 114.3 0.0 2.0 2 0 0 2 2 2 2 LamB/YcsF family Homeobox_KN PF05920.6 EEQ76536.1 - 3.2e-15 55.5 0.2 7e-15 54.4 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EEQ76536.1 - 0.00046 19.7 1.0 0.00079 19.0 0.0 1.9 2 0 0 2 2 2 1 Homeobox domain zf-C2H2_4 PF13894.1 EEQ76536.1 - 0.002 18.3 2.0 0.002 18.3 1.4 5.0 5 1 0 5 5 5 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ76536.1 - 0.0051 17.0 22.7 0.019 15.3 1.7 4.4 3 1 1 4 4 4 3 Zinc finger, C2H2 type HA PF03457.9 EEQ76536.1 - 0.008 16.2 0.5 0.031 14.3 0.1 2.2 2 0 0 2 2 2 1 Helicase associated domain zf-H2C2_2 PF13465.1 EEQ76536.1 - 0.37 11.1 4.9 12 6.4 0.0 4.2 4 0 0 4 4 4 0 Zinc-finger double domain UQ_con PF00179.21 EEQ76537.1 - 1.7e-11 43.6 0.0 2.9e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EEQ76537.1 - 0.15 11.9 0.1 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 RWD domain 2OG-FeII_Oxy_2 PF13532.1 EEQ76539.1 - 3.3e-35 121.6 0.2 4.5e-35 121.2 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 EEQ76539.1 - 2.1e-05 24.3 6.6 4e-05 23.4 4.5 1.5 1 0 0 1 1 1 1 GRF zinc finger CUE PF02845.11 EEQ76539.1 - 0.0043 16.5 0.0 0.0088 15.5 0.0 1.6 1 0 0 1 1 1 1 CUE domain WD40 PF00400.27 EEQ76540.1 - 6.6e-22 76.5 24.2 5.7e-09 35.5 0.1 6.5 6 1 1 7 7 7 6 WD domain, G-beta repeat DUF2415 PF10313.4 EEQ76540.1 - 0.13 11.9 0.1 0.47 10.1 0.1 1.9 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) MFS_1 PF07690.11 EEQ76541.1 - 5.1e-38 130.6 34.4 5.1e-38 130.6 23.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ76541.1 - 7.9e-12 44.4 24.3 5e-11 41.8 16.8 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Aldolase_II PF00596.16 EEQ76544.1 - 2.6e-40 137.9 0.1 5.2e-40 137.0 0.1 1.5 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain 4HBT_3 PF13622.1 EEQ76545.1 - 1.4e-44 152.8 1.4 2e-44 152.2 1.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EEQ76545.1 - 1.1e-21 76.8 0.0 2.3e-11 43.4 0.0 3.5 3 1 1 4 4 4 3 Acyl-CoA thioesterase DUF3445 PF11927.3 EEQ76547.1 - 1.5e-40 139.1 0.0 4.1e-25 88.6 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3445) HSP70 PF00012.15 EEQ76549.1 - 7.4e-11 40.6 0.3 1.9e-09 36.0 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 EEQ76549.1 - 0.017 14.7 0.1 0.039 13.6 0.1 1.5 1 0 0 1 1 1 0 SAP30 zinc-finger MreB_Mbl PF06723.8 EEQ76549.1 - 0.17 10.4 0.2 1 7.8 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein DUF605 PF04652.11 EEQ76549.1 - 9.7 5.4 10.3 13 5.0 7.1 1.1 1 0 0 1 1 1 0 Vta1 like N2227 PF07942.7 EEQ76551.1 - 2.5e-89 298.8 0.0 3.2e-89 298.5 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EEQ76551.1 - 4.5e-06 26.4 0.0 1.6e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Fungal_trans PF04082.13 EEQ76555.1 - 1.8e-25 89.2 1.3 3e-25 88.5 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ76555.1 - 9e-06 25.4 12.8 1.8e-05 24.5 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prefoldin_2 PF01920.15 EEQ76556.1 - 2.9e-24 84.8 6.8 3.5e-24 84.5 4.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit Imm7 PF15588.1 EEQ76556.1 - 0.012 15.6 0.5 0.021 14.8 0.3 1.4 1 0 0 1 1 1 0 Immunity protein 7 Spore_III_AF PF09581.5 EEQ76556.1 - 0.016 15.1 1.6 0.019 14.8 1.1 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Prefoldin PF02996.12 EEQ76556.1 - 0.034 13.7 0.6 0.034 13.7 0.4 2.1 1 1 1 2 2 2 0 Prefoldin subunit eIF-4B PF06273.6 EEQ76556.1 - 0.036 12.8 4.8 0.041 12.6 3.4 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Rbsn PF11464.3 EEQ76556.1 - 0.047 13.2 1.2 0.047 13.2 0.8 1.8 2 0 0 2 2 1 0 Rabenosyn Rab binding domain SPX PF03105.14 EEQ76556.1 - 0.27 10.9 5.2 0.33 10.6 3.6 1.1 1 0 0 1 1 1 0 SPX domain AATF-Che1 PF13339.1 EEQ76556.1 - 0.29 11.3 0.1 0.29 11.3 0.1 2.1 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor AAA_23 PF13476.1 EEQ76556.1 - 0.29 11.4 5.8 0.38 11.0 4.0 1.1 1 0 0 1 1 1 0 AAA domain Spc24 PF08286.6 EEQ76556.1 - 0.3 10.7 7.2 4.7 6.9 2.1 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 CASP_C PF08172.7 EEQ76556.1 - 0.33 9.9 6.5 3.8 6.4 0.1 2.1 2 0 0 2 2 2 0 CASP C terminal Tektin PF03148.9 EEQ76556.1 - 1.2 7.6 11.9 1.8 7.0 2.4 2.0 1 1 1 2 2 2 0 Tektin family EMP24_GP25L PF01105.19 EEQ76556.1 - 1.3 8.7 3.7 1.8 8.2 2.6 1.4 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF4164 PF13747.1 EEQ76556.1 - 2.2 8.4 12.5 1.9 8.6 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Seryl_tRNA_N PF02403.17 EEQ76556.1 - 3.2 7.8 10.3 0.8 9.7 0.7 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EEQ76556.1 - 4.9 6.6 16.8 33 3.9 11.6 1.9 1 1 0 1 1 1 0 IncA protein Rabaptin PF03528.10 EEQ76556.1 - 6.2 6.7 13.3 6.4 6.7 5.8 2.1 2 0 0 2 2 2 0 Rabaptin DivIC PF04977.10 EEQ76556.1 - 6.5 6.3 11.8 15 5.1 4.2 2.2 2 0 0 2 2 2 0 Septum formation initiator ADIP PF11559.3 EEQ76556.1 - 7.6 6.4 11.8 6.2 6.7 0.2 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding TBPIP PF07106.8 EEQ76556.1 - 8.9 5.8 11.5 0.24 10.9 0.4 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ATG27 PF09451.5 EEQ76557.1 - 2.7e-62 210.4 0.8 5.5e-62 209.4 0.6 1.6 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 EEQ76557.1 - 0.0019 17.9 0.0 0.033 13.9 0.0 2.2 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat Pilus_CpaD PF09476.5 EEQ76559.1 - 0.089 12.2 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) Pribosyl_synth PF14572.1 EEQ76560.1 - 7.5e-41 139.8 1.8 7.1e-36 123.6 0.6 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EEQ76560.1 - 5.2e-34 116.4 0.0 2.3e-33 114.3 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EEQ76560.1 - 4.9e-12 45.6 0.2 2.6e-11 43.3 0.1 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EEQ76560.1 - 0.0033 16.6 0.1 0.0053 15.9 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF218 PF02698.12 EEQ76560.1 - 0.11 12.0 0.2 1.4 8.3 0.1 2.5 2 1 0 2 2 2 0 DUF218 domain ubiquitin PF00240.18 EEQ76562.1 - 0.0012 18.2 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 EEQ76562.1 - 0.037 14.6 0.0 0.07 13.7 0.0 1.5 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD MIP-T3 PF10243.4 EEQ76562.1 - 1.8 6.9 19.5 2.3 6.5 13.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PIG-H PF10181.4 EEQ76563.1 - 2.6e-27 94.2 0.4 3.9e-27 93.6 0.3 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component PseudoU_synth_1 PF01416.15 EEQ76564.1 - 9.3e-28 96.7 0.0 1.7e-19 70.1 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase BBP1_C PF15272.1 EEQ76564.1 - 0.19 11.2 1.2 0.42 10.1 0.8 1.5 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Arc PF03869.9 EEQ76565.1 - 0.0067 16.0 0.2 0.44 10.2 0.0 2.6 2 0 0 2 2 2 2 Arc-like DNA binding domain HNH_2 PF13391.1 EEQ76566.1 - 3.3e-09 36.3 0.6 1.2e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease AChE_tetra PF08674.5 EEQ76566.1 - 5.2 6.6 6.9 3.5 7.2 0.6 2.4 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain Tubulin_3 PF14881.1 EEQ76567.1 - 1.9e-86 288.1 0.2 2.9e-86 287.5 0.2 1.3 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 EEQ76567.1 - 6.2e-43 145.5 0.0 1.3e-42 144.4 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 EEQ76567.1 - 2.7e-07 30.6 0.0 0.0016 18.3 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Spc7 PF08317.6 EEQ76568.1 - 0.085 11.5 8.2 0.16 10.5 5.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein HR1 PF02185.11 EEQ76568.1 - 3.5 7.4 21.5 8.5 6.1 3.0 4.2 4 0 0 4 4 4 0 Hr1 repeat Kinetocho_Slk19 PF12709.2 EEQ76568.1 - 4.6 7.3 11.8 3.3 7.8 5.9 2.4 2 0 0 2 2 2 0 Central kinetochore-associated DUF2347 PF09804.4 EEQ76569.1 - 6.2e-106 353.7 0.0 8.1e-106 353.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 EEQ76569.1 - 3.1e-52 177.2 0.0 4.7e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.4 EEQ76569.1 - 5.4e-05 21.8 0.0 0.023 13.1 0.0 2.6 2 1 0 2 2 2 2 Transport protein Avl9 SPA PF08616.5 EEQ76569.1 - 0.00046 19.8 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.7 EEQ76569.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.8 2 1 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking EBP PF05241.7 EEQ76570.1 - 1e-67 226.9 10.8 1.3e-67 226.5 7.5 1.0 1 0 0 1 1 1 1 Emopamil binding protein VIT1 PF01988.14 EEQ76570.1 - 0.0048 16.4 1.4 0.0075 15.7 1.0 1.2 1 0 0 1 1 1 1 VIT family SNF2_N PF00176.18 EEQ76572.1 - 6.4e-67 225.4 0.0 9.7e-67 224.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ76572.1 - 2.4e-11 43.3 0.0 5.4e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_2 PF07724.9 EEQ76573.1 - 3.3e-47 160.5 0.0 2e-45 154.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EEQ76573.1 - 1e-27 96.9 0.0 4.4e-15 56.0 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EEQ76573.1 - 3.3e-24 84.6 0.3 1.1e-23 82.8 0.2 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 EEQ76573.1 - 3.1e-16 59.9 9.4 4.3e-06 26.8 0.0 6.0 3 2 2 6 6 6 2 AAA ATPase domain AAA_5 PF07728.9 EEQ76573.1 - 3.7e-16 59.1 0.0 4e-10 39.5 0.0 3.2 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEQ76573.1 - 6.8e-16 58.6 0.1 2.1e-05 24.6 0.0 4.5 3 1 1 4 4 4 2 AAA domain Sigma54_activat PF00158.21 EEQ76573.1 - 2.5e-10 40.0 0.0 6.5e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 EEQ76573.1 - 1.3e-08 35.6 5.4 0.0031 18.3 0.5 4.0 3 2 0 3 3 2 2 AAA domain Arch_ATPase PF01637.13 EEQ76573.1 - 7e-08 32.4 0.5 0.015 14.9 0.2 4.3 2 2 0 3 3 3 1 Archaeal ATPase AAA_19 PF13245.1 EEQ76573.1 - 1.9e-07 30.7 0.0 0.02 14.6 0.0 3.4 2 0 0 2 2 2 2 Part of AAA domain IstB_IS21 PF01695.12 EEQ76573.1 - 2.9e-07 30.0 0.1 0.027 13.9 0.0 2.9 2 1 0 3 3 3 2 IstB-like ATP binding protein Clp_N PF02861.15 EEQ76573.1 - 1.1e-06 28.4 3.2 0.00051 19.9 0.0 4.0 3 0 0 3 3 3 1 Clp amino terminal domain AAA_18 PF13238.1 EEQ76573.1 - 5e-06 26.8 7.2 0.0098 16.2 0.0 4.0 4 1 0 4 4 3 2 AAA domain Mg_chelatase PF01078.16 EEQ76573.1 - 1.1e-05 24.6 0.1 0.081 12.0 0.1 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EEQ76573.1 - 2.3e-05 24.4 0.9 0.27 11.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EEQ76573.1 - 2.5e-05 24.1 0.1 0.19 11.6 0.0 3.4 3 0 0 3 3 2 2 AAA domain T2SE PF00437.15 EEQ76573.1 - 3.4e-05 22.8 0.0 0.0042 16.0 0.0 2.7 2 1 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.22 EEQ76573.1 - 3.7e-05 24.0 0.8 0.37 11.0 0.0 3.8 3 0 0 3 3 3 1 ABC transporter RNA_helicase PF00910.17 EEQ76573.1 - 3.8e-05 23.7 0.0 0.31 11.2 0.0 2.6 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 EEQ76573.1 - 5.1e-05 23.0 0.0 0.46 10.1 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_3 PF07726.6 EEQ76573.1 - 0.00017 21.1 0.0 0.77 9.3 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EEQ76573.1 - 0.00041 19.5 0.1 0.035 13.2 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin AAA_25 PF13481.1 EEQ76573.1 - 0.00062 19.2 0.8 1.9 7.8 0.0 3.7 3 1 0 4 4 3 2 AAA domain AAA_29 PF13555.1 EEQ76573.1 - 0.00074 18.9 0.0 0.75 9.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain ResIII PF04851.10 EEQ76573.1 - 0.001 18.9 0.2 0.78 9.5 0.0 3.8 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit DUF258 PF03193.11 EEQ76573.1 - 0.0015 17.7 0.0 0.62 9.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 EEQ76573.1 - 0.0017 18.0 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EEQ76573.1 - 0.0019 17.9 0.0 0.24 11.1 0.0 3.3 3 0 0 3 3 3 1 NTPase Torsin PF06309.6 EEQ76573.1 - 0.0026 17.6 0.0 0.014 15.2 0.0 2.1 2 0 0 2 2 2 1 Torsin NACHT PF05729.7 EEQ76573.1 - 0.0043 16.7 0.0 0.55 9.8 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 EEQ76573.1 - 0.005 16.3 5.7 0.29 10.5 0.0 4.3 5 1 1 6 6 6 1 AAA-like domain SRP54 PF00448.17 EEQ76573.1 - 0.013 14.9 0.1 5.3 6.4 0.0 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_21 PF13304.1 EEQ76573.1 - 0.019 14.9 0.1 2.1 8.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain cobW PF02492.14 EEQ76573.1 - 0.034 13.5 0.2 17 4.7 0.0 3.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 EEQ76573.1 - 0.037 13.6 0.0 14 5.3 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 EEQ76573.1 - 0.043 13.7 0.3 1 9.3 0.0 3.3 4 0 0 4 4 2 0 50S ribosome-binding GTPase Glyoxalase_2 PF12681.2 EEQ76573.1 - 0.043 14.4 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 Glyoxalase-like domain ATP_bind_1 PF03029.12 EEQ76573.1 - 0.1 12.1 0.0 18 4.7 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF1192 PF06698.6 EEQ76573.1 - 0.21 11.4 9.0 0.87 9.4 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) IncA PF04156.9 EEQ76573.1 - 0.27 10.7 4.4 0.87 9.1 3.1 1.9 1 0 0 1 1 1 0 IncA protein Viral_P18 PF04521.8 EEQ76573.1 - 1.3 8.5 5.5 15 5.0 0.1 2.5 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein AAA_23 PF13476.1 EEQ76573.1 - 1.3 9.3 0.0 1.3 9.3 0.0 4.0 3 2 0 3 3 2 0 AAA domain DUF607 PF04678.8 EEQ76573.1 - 2.6 7.9 4.5 3.8 7.3 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF607 zf-CCHC PF00098.18 EEQ76576.1 - 0.00063 19.5 0.9 0.0011 18.7 0.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EEQ76576.1 - 0.015 15.0 0.9 0.039 13.6 0.6 1.7 1 0 0 1 1 1 0 Zinc knuckle HSP70 PF00012.15 EEQ76577.1 - 5.9e-55 186.3 10.3 3.7e-51 173.7 0.2 3.3 3 1 0 3 3 3 2 Hsp70 protein SSP160 PF06933.6 EEQ76577.1 - 0.94 7.3 21.4 0.52 8.2 4.7 2.3 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 EEQ76577.1 - 4 7.2 22.2 0.59 9.9 1.7 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Peptidase_M35 PF02102.10 EEQ76578.1 - 5.6e-130 433.1 5.0 6.7e-130 432.9 3.4 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EEQ76578.1 - 4.3e-07 30.5 0.1 8.9e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Ribosomal_S2 PF00318.15 EEQ76580.1 - 4.1e-44 150.3 0.0 1.5e-23 83.1 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_S15 PF00312.17 EEQ76581.1 - 2.3e-16 59.3 0.2 5e-16 58.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 DUF3504 PF12012.3 EEQ76582.1 - 0.074 12.8 3.7 0.081 12.6 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) Neur_chan_memb PF02932.11 EEQ76582.1 - 0.53 10.1 5.3 0.6 9.9 3.7 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SRP-alpha_N PF04086.8 EEQ76582.1 - 3.8 6.8 11.1 4.5 6.5 7.7 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CytochromB561_N PF09786.4 EEQ76582.1 - 5.8 5.2 7.2 6.4 5.1 5.0 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal FGF-BP1 PF06473.7 EEQ76582.1 - 8.6 5.8 10.0 10 5.6 7.0 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) DEAD PF00270.24 EEQ76584.1 - 1.4e-35 122.2 0.0 8.8e-35 119.6 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EEQ76584.1 - 2.7e-22 78.0 0.0 5e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EEQ76584.1 - 0.0057 16.5 1.0 0.031 14.1 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EEQ76584.1 - 0.059 13.5 0.3 0.52 10.4 0.2 2.3 1 1 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.7 EEQ76584.1 - 7.6 6.3 11.8 11 5.8 8.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CTP_transf_1 PF01148.15 EEQ76585.1 - 2.1e-13 50.5 9.3 1.7e-12 47.5 3.1 2.0 1 1 1 2 2 2 2 Cytidylyltransferase family XPG_I PF00867.13 EEQ76586.1 - 8.4e-06 25.7 0.0 2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 XPG I-region Actin PF00022.14 EEQ76587.1 - 7e-23 80.6 0.0 3.6e-21 75.0 0.0 2.5 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EEQ76587.1 - 0.031 12.8 0.0 0.27 9.8 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein Aldose_epim PF01263.15 EEQ76589.1 - 1.6e-51 175.2 0.9 2.1e-51 174.8 0.6 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Glyco_hydro_72 PF03198.9 EEQ76592.1 - 1.6e-53 181.7 0.0 4.8e-32 111.2 0.0 2.1 2 0 0 2 2 2 2 Glucanosyltransferase Sds3 PF08598.6 EEQ76595.1 - 3.8e-55 186.5 5.9 3.8e-55 186.5 4.1 1.8 2 1 0 2 2 2 1 Sds3-like UBN2_2 PF14227.1 EEQ76595.1 - 0.021 14.4 0.4 0.16 11.5 0.3 2.3 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type CFEM PF05730.6 EEQ76597.1 - 0.0002 21.1 4.7 0.0002 21.1 3.3 2.2 2 0 0 2 2 2 1 CFEM domain DUF2236 PF09995.4 EEQ76598.1 - 1.4e-36 126.0 0.0 1.9e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) CENP-B_dimeris PF09026.5 EEQ76599.1 - 0.0023 18.1 4.3 0.0023 18.1 3.0 4.8 4 1 0 4 4 4 2 Centromere protein B dimerisation domain Pkinase PF00069.20 EEQ76600.1 - 1e-09 37.9 0.0 2.3e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ76600.1 - 0.0064 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ76600.1 - 0.019 14.7 0.0 0.049 13.3 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family TAN PF11640.3 EEQ76600.1 - 0.048 13.3 0.2 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair DUF2752 PF10825.3 EEQ76601.1 - 0.0042 17.0 1.1 0.0075 16.2 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2752) MLANA PF14991.1 EEQ76601.1 - 0.018 15.0 0.0 0.052 13.5 0.0 1.7 1 0 0 1 1 1 0 Protein melan-A Colicin PF01024.14 EEQ76601.1 - 0.037 13.6 0.1 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Colicin pore forming domain FAM176 PF14851.1 EEQ76601.1 - 0.1 12.2 0.6 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 FAM176 family BTB PF00651.26 EEQ76603.1 - 2.9e-05 23.9 0.0 0.00011 22.1 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Peptidase_S24 PF00717.18 EEQ76605.1 - 1.6e-07 30.8 0.1 2.9e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like UQ_con PF00179.21 EEQ76606.1 - 5.4e-40 136.0 0.0 6e-40 135.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEQ76606.1 - 2.5e-08 33.7 0.0 3.2e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEQ76606.1 - 0.033 14.0 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 EEQ76606.1 - 0.056 13.1 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain RabGAP-TBC PF00566.13 EEQ76607.1 - 4.8e-40 137.3 0.0 5.7e-39 133.7 0.0 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Ferric_reduct PF01794.14 EEQ76609.1 - 1e-18 67.5 14.2 7.6e-18 64.7 7.4 2.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EEQ76609.1 - 1.6e-18 67.0 0.0 1.2e-15 57.7 0.0 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EEQ76609.1 - 1.3e-14 53.9 0.0 7.7e-14 51.4 0.0 2.2 1 1 0 1 1 1 1 FAD-binding domain zf-CCHC PF00098.18 EEQ76610.1 - 3.7e-11 42.3 10.0 4.1e-05 23.3 2.1 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EEQ76610.1 - 8.9e-09 34.8 0.2 1.7e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EEQ76610.1 - 4e-06 26.4 6.4 0.00055 19.6 1.7 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 EEQ76610.1 - 1.4e-05 24.5 0.2 3.5e-05 23.3 0.2 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 EEQ76610.1 - 0.00046 19.7 6.2 0.16 11.6 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 EEQ76610.1 - 0.0071 15.9 11.6 0.18 11.5 1.2 3.1 2 1 1 3 3 3 2 Zinc knuckle eIF3g PF12353.3 EEQ76610.1 - 2.9 7.8 7.3 4.7 7.1 1.1 3.1 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G HCO3_cotransp PF00955.16 EEQ76611.1 - 1.5e-71 241.6 12.0 1.5e-40 139.3 3.1 2.0 1 1 1 2 2 2 2 HCO3- transporter family DEAD PF00270.24 EEQ76612.1 - 5.8e-39 133.2 0.0 1e-38 132.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ76612.1 - 8.3e-28 96.0 0.1 1.5e-27 95.2 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EEQ76612.1 - 0.00013 20.8 0.0 0.00022 20.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EEQ76612.1 - 0.02 14.7 0.0 0.052 13.3 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit tRNA-synt_1c PF00749.16 EEQ76617.1 - 4.8e-99 330.9 0.0 6.1e-99 330.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EEQ76617.1 - 1.1e-39 135.9 0.0 1.6e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EEQ76617.1 - 2.2e-07 31.2 0.0 6.5e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEQ76617.1 - 0.00071 19.4 0.1 0.0018 18.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 EEQ76617.1 - 0.023 13.8 0.2 0.054 12.6 0.1 1.5 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF1793 PF08760.6 EEQ76618.1 - 7.2e-72 240.7 0.0 1.3e-71 239.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Daxx PF03344.10 EEQ76618.1 - 1.1 7.7 8.3 1.5 7.1 5.8 1.1 1 0 0 1 1 1 0 Daxx Family Stm1_N PF09598.5 EEQ76619.1 - 7.9e-17 61.7 5.8 7.9e-17 61.7 4.0 4.4 3 2 1 4 4 4 1 Stm1 3HCDH_N PF02737.13 EEQ76620.1 - 0.16 11.5 0.7 0.22 11.1 0.5 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SR-25 PF10500.4 EEQ76620.1 - 0.79 9.1 14.3 1.1 8.6 9.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein bZIP_1 PF00170.16 EEQ76621.1 - 9.6e-06 25.4 8.1 2.1e-05 24.4 5.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEQ76621.1 - 0.005 16.6 7.5 0.005 16.6 5.2 2.4 2 0 0 2 2 2 1 Basic region leucine zipper Effector_1 PF04518.7 EEQ76621.1 - 0.021 13.8 0.9 0.038 12.9 0.6 1.3 1 0 0 1 1 1 0 Effector from type III secretion system DUF4407 PF14362.1 EEQ76621.1 - 0.13 11.2 8.2 0.45 9.4 2.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Glutaredoxin2_C PF04399.8 EEQ76621.1 - 0.14 11.7 0.6 0.24 11.0 0.4 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Pex19 PF04614.7 EEQ76622.1 - 5.4e-68 229.3 1.8 5.4e-68 229.3 1.3 2.2 2 0 0 2 2 2 1 Pex19 protein family VPS11_C PF12451.3 EEQ76623.1 - 5.5 6.9 7.2 1.5 8.6 0.8 2.8 2 1 1 3 3 3 0 Vacuolar protein sorting protein 11 C terminal ABC_tran PF00005.22 EEQ76624.1 - 9.7e-36 123.0 0.0 8.7e-21 74.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEQ76624.1 - 1.2e-21 77.3 23.6 1.4e-12 47.6 1.5 4.3 3 1 1 4 4 4 3 ABC transporter transmembrane region SMC_N PF02463.14 EEQ76624.1 - 4.8e-11 42.3 1.9 0.0012 18.1 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EEQ76624.1 - 4e-06 26.3 0.0 0.046 13.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EEQ76624.1 - 5.1e-06 26.6 0.0 5.3 6.9 0.0 4.3 4 0 0 4 4 4 1 AAA domain T2SE PF00437.15 EEQ76624.1 - 8.5e-05 21.5 1.0 0.096 11.5 0.2 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.1 EEQ76624.1 - 0.00012 22.2 0.0 0.27 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EEQ76624.1 - 0.00038 20.5 0.3 0.12 12.3 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 EEQ76624.1 - 0.0059 16.0 0.1 1.1 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 EEQ76624.1 - 0.0068 15.9 7.3 0.094 12.2 0.1 3.3 3 0 0 3 3 3 1 P-loop containing region of AAA domain Miro PF08477.8 EEQ76624.1 - 0.011 16.2 0.0 1.1 9.8 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein DEAD PF00270.24 EEQ76624.1 - 0.011 15.2 0.2 11 5.4 0.0 3.3 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_19 PF13245.1 EEQ76624.1 - 0.014 15.0 0.8 0.31 10.8 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain Zot PF05707.7 EEQ76624.1 - 0.02 14.3 0.1 0.4 10.1 0.0 2.7 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) DUF2075 PF09848.4 EEQ76624.1 - 0.027 13.4 0.1 3 6.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.12 EEQ76624.1 - 0.031 14.0 1.8 0.051 13.4 0.1 2.2 3 0 0 3 3 2 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EEQ76624.1 - 0.037 13.4 0.1 6.9 6.0 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.14 EEQ76624.1 - 0.038 13.4 1.8 0.44 9.9 0.3 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.1 EEQ76624.1 - 0.039 13.8 0.1 15 5.5 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 EEQ76624.1 - 0.079 12.6 0.5 7.8 6.1 0.2 2.6 2 0 0 2 2 2 0 NACHT domain Pox_A32 PF04665.7 EEQ76624.1 - 0.087 12.1 1.2 2.1 7.5 0.2 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Zeta_toxin PF06414.7 EEQ76624.1 - 0.093 11.8 0.1 2.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.1 EEQ76624.1 - 0.11 12.8 0.9 1.9 8.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EEQ76624.1 - 0.21 10.7 0.3 16 4.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EEQ76624.1 - 0.24 11.0 0.1 23 4.6 0.0 2.8 3 0 0 3 3 3 0 Archaeal ATPase Mid2 PF04478.7 EEQ76625.1 - 2.7e-05 23.6 0.2 2.7e-05 23.6 0.1 2.0 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 EEQ76625.1 - 0.042 13.1 1.0 0.042 13.1 0.7 2.5 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Syndecan PF01034.15 EEQ76625.1 - 0.18 11.5 0.1 0.37 10.4 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain Pex14_N PF04695.8 EEQ76625.1 - 4.2 7.4 13.7 13 5.8 9.4 1.9 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF605 PF04652.11 EEQ76625.1 - 4.5 6.5 15.6 5.9 6.1 10.8 1.1 1 0 0 1 1 1 0 Vta1 like Shisa PF13908.1 EEQ76625.1 - 4.9 7.2 10.1 2.3 8.3 5.5 1.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator CRA PF06589.6 EEQ76625.1 - 6 6.1 6.6 1 8.6 0.1 2.3 2 1 1 3 3 3 0 Circumsporozoite-related antigen (CRA) Herpes_BLLF1 PF05109.8 EEQ76625.1 - 9.1 4.1 31.1 14 3.5 21.6 1.3 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF1996 PF09362.5 EEQ76627.1 - 1.5e-73 247.3 0.3 2.6e-73 246.5 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Y_phosphatase PF00102.22 EEQ76628.1 - 3.6e-52 177.0 0.0 4.9e-51 173.3 0.0 2.1 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EEQ76628.1 - 5e-05 23.3 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 EEQ76628.1 - 0.01 15.4 0.0 0.03 13.8 0.0 1.8 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EEQ76628.1 - 0.02 15.1 0.0 0.058 13.6 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family VanZ PF04892.7 EEQ76629.1 - 5.3e-12 45.8 0.0 6.7e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 VanZ like family Bromodomain PF00439.20 EEQ76630.1 - 1.1e-20 73.3 2.0 8.1e-20 70.5 0.2 2.6 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.8 EEQ76630.1 - 1e-06 28.3 0.0 3.3e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 Bromodomain associated V_ATPase_I PF01496.14 EEQ76630.1 - 3.2 5.5 5.0 5.1 4.8 3.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APH PF01636.18 EEQ76631.1 - 4.5e-08 33.1 0.0 9.2e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family SOR PF07682.6 EEQ76631.1 - 0.044 12.3 0.0 0.11 11.0 0.0 1.6 2 0 0 2 2 2 0 Sulphur oxygenase reductase Lgl_C PF08596.5 EEQ76632.1 - 8.1e-125 416.3 0.0 2.6e-124 414.6 0.0 1.8 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EEQ76632.1 - 0.00028 20.6 1.1 0.15 11.9 0.1 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat ASF1_hist_chap PF04729.8 EEQ76633.1 - 2.6e-68 228.5 0.0 3.7e-68 227.9 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.7 EEQ76633.1 - 0.1 10.4 24.9 0.14 10.0 17.3 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EEQ76633.1 - 1.3 6.9 14.7 1.8 6.5 10.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Suf PF05843.9 EEQ76634.1 - 4.9e-82 275.8 0.0 4.9e-82 275.8 0.0 4.3 6 1 1 7 7 7 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EEQ76634.1 - 0.0002 21.7 0.0 0.044 14.4 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ76634.1 - 0.00024 21.7 0.0 0.02 15.5 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat HAT PF02184.11 EEQ76634.1 - 0.0074 16.0 0.1 0.0074 16.0 0.1 3.0 4 0 0 4 4 4 1 HAT (Half-A-TPR) repeat Retinal PF15449.1 EEQ76635.1 - 1.9 6.0 9.8 2.1 5.8 6.8 1.0 1 0 0 1 1 1 0 Retinal protein DUF605 PF04652.11 EEQ76635.1 - 7 5.9 6.9 7.4 5.8 4.8 1.0 1 0 0 1 1 1 0 Vta1 like Piwi PF02171.12 EEQ76636.1 - 2.8e-72 243.2 0.0 3.9e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EEQ76636.1 - 1.8e-17 62.4 0.0 4.3e-17 61.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EEQ76636.1 - 5.1e-14 51.7 0.1 1.2e-13 50.5 0.0 1.6 2 0 0 2 2 2 1 PAZ domain Transposase_mut PF00872.13 EEQ76636.1 - 0.032 12.7 0.0 0.069 11.6 0.0 1.4 1 0 0 1 1 1 0 Transposase, Mutator family THUMP PF02926.12 EEQ76637.1 - 3e-09 36.8 0.2 1.6e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 THUMP domain TPP_enzyme_N PF02776.13 EEQ76638.1 - 2.8e-35 121.3 0.0 5.4e-35 120.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EEQ76638.1 - 2.2e-23 82.5 0.0 8.4e-23 80.6 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EEQ76638.1 - 7.1e-15 54.8 0.0 1.7e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EEQ76638.1 - 0.0034 16.1 0.1 0.0059 15.3 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Fungal_trans PF04082.13 EEQ76639.1 - 3.6e-31 107.9 0.0 8.8e-31 106.7 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ76639.1 - 2.6e-11 43.2 12.6 4.2e-11 42.5 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 EEQ76639.1 - 0.068 13.1 0.1 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Gal4-like dimerisation domain Zip PF02535.17 EEQ76642.1 - 9.2e-06 24.8 0.0 1e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter TMEM117 PF15113.1 EEQ76642.1 - 0.06 11.9 0.0 0.078 11.5 0.0 1.1 1 0 0 1 1 1 0 TMEM117 protein family Cation_efflux PF01545.16 EEQ76643.1 - 0.031 13.3 8.0 0.12 11.4 0.6 2.7 1 1 1 2 2 2 0 Cation efflux family ADPrib_exo_Tox PF03496.9 EEQ76644.1 - 0.1 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme Peptidase_M24 PF00557.19 EEQ76647.1 - 9.1e-45 152.7 0.1 1.2e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EEQ76647.1 - 0.0011 18.8 4.8 0.0011 18.8 3.3 2.2 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 EEQ76647.1 - 0.16 11.6 4.5 0.41 10.3 3.1 1.8 1 0 0 1 1 1 0 HIT zinc finger FAD_binding_3 PF01494.14 EEQ76648.1 - 1.9e-18 66.6 0.0 1.4e-17 63.8 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEQ76648.1 - 2.9e-07 29.7 0.0 0.00014 20.8 0.1 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EEQ76648.1 - 2.2e-05 24.7 0.0 0.00091 19.5 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEQ76648.1 - 6.2e-05 22.9 0.0 0.00016 21.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EEQ76648.1 - 8.3e-05 21.8 0.1 0.00032 19.9 0.0 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEQ76648.1 - 0.0003 20.7 0.1 0.001 19.0 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEQ76648.1 - 0.00062 18.7 0.0 0.00081 18.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 EEQ76648.1 - 0.0031 16.0 0.1 0.0051 15.3 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein 3HCDH_N PF02737.13 EEQ76648.1 - 0.032 13.8 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 EEQ76648.1 - 0.11 11.5 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family SE PF08491.5 EEQ76648.1 - 0.17 10.6 0.0 0.28 9.9 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase DUF904 PF06005.7 EEQ76650.1 - 0.09 13.0 0.6 0.22 11.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) COMP PF11598.3 EEQ76650.1 - 0.18 11.8 1.6 0.27 11.3 0.3 1.8 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein OTT_1508_deam PF14441.1 EEQ76652.1 - 0.019 14.7 0.0 0.044 13.5 0.0 1.7 1 0 0 1 1 1 0 OTT_1508-like deaminase NPCC PF08058.6 EEQ76652.1 - 0.071 12.9 1.2 0.14 11.9 0.9 1.5 1 0 0 1 1 1 0 Nuclear pore complex component DUF3506 PF12014.3 EEQ76653.1 - 8.7e-52 174.5 0.0 2e-51 173.3 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 EEQ76653.1 - 7.4e-09 35.1 0.3 2.1e-08 33.7 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ76653.1 - 1.4e-06 27.7 0.6 3.4e-06 26.5 0.2 1.8 2 0 0 2 2 2 1 F-box domain ECH PF00378.15 EEQ76654.1 - 8e-20 71.0 0.0 9.7e-20 70.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EEQ76654.1 - 0.035 13.8 0.0 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 IncA PF04156.9 EEQ76656.1 - 0.00021 20.9 4.9 0.00021 20.9 3.4 5.2 2 1 3 5 5 5 4 IncA protein Reo_sigmaC PF04582.7 EEQ76656.1 - 0.0079 15.4 18.5 0.36 9.9 1.8 2.5 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Surfac_D-trimer PF09006.6 EEQ76656.1 - 0.57 9.9 4.6 9 6.1 0.0 3.9 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation DUF3584 PF12128.3 EEQ76656.1 - 2.9 5.0 50.0 0.022 12.1 20.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) Glyco_hydro_25 PF01183.15 EEQ76657.1 - 4.6e-15 55.8 0.0 5.4e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 DUF1769 PF08588.5 EEQ76658.1 - 2.4e-28 97.8 0.0 4.5e-28 96.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) DUF2457 PF10446.4 EEQ76658.1 - 9 4.9 8.4 12 4.5 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Iso_dh PF00180.15 EEQ76659.1 - 1.4e-94 316.9 0.0 2.2e-93 312.9 0.0 1.9 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ICMT PF04140.9 EEQ76659.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family LVIVD PF08309.6 EEQ76662.1 - 1.7e-10 39.7 3.5 0.021 13.8 0.2 5.4 5 0 0 5 5 5 4 LVIVD repeat PQQ_3 PF13570.1 EEQ76662.1 - 3.4 8.0 0.0 3.4 8.0 0.0 3.7 5 0 0 5 5 5 0 PQQ-like domain Ribosomal_S8 PF00410.14 EEQ76665.1 - 2.2e-24 85.7 0.0 4.8e-24 84.6 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S8 DUF1748 PF08520.5 EEQ76666.1 - 3.3e-15 55.4 0.0 8.7e-15 54.1 0.0 1.7 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1748) DUF1748 PF08520.5 EEQ76667.1 - 0.063 12.9 0.1 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) Zn_dep_PLPC PF00882.13 EEQ76667.1 - 0.07 12.7 0.1 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Zinc dependent phospholipase C PK PF00224.16 EEQ76668.1 - 9.5e-168 557.2 4.8 1.2e-167 556.8 3.3 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EEQ76668.1 - 5.7e-29 100.0 0.0 2.5e-28 97.9 0.0 2.1 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EEQ76668.1 - 8.4e-05 21.5 1.3 0.00026 19.9 0.8 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EEQ76668.1 - 0.0094 14.8 0.2 0.64 8.8 0.0 2.9 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain PIP5K PF01504.13 EEQ76669.1 - 2e-46 158.1 0.1 3.5e-30 104.9 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EEQ76669.1 - 4.8e-30 104.6 0.0 7.1e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EEQ76669.1 - 7.7e-15 54.5 5.2 7.7e-15 54.5 3.6 2.0 2 0 0 2 2 2 1 FYVE zinc finger C1_1 PF00130.17 EEQ76669.1 - 0.0044 16.7 3.2 0.01 15.5 2.2 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Glyco_transf_5 PF08323.6 EEQ76669.1 - 0.2 11.1 0.0 0.5 9.8 0.0 1.6 1 0 0 1 1 1 0 Starch synthase catalytic domain TPP1 PF10341.4 EEQ76670.1 - 4.6e-17 61.9 0.0 8.8e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD Ank_2 PF12796.2 EEQ76671.1 - 2.4e-51 172.0 0.1 1.1e-13 51.2 0.0 5.4 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ76671.1 - 2.9e-38 127.8 0.0 0.00087 18.9 0.0 9.7 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.1 EEQ76671.1 - 4.6e-38 128.9 0.8 7.7e-09 35.8 0.0 6.1 1 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ76671.1 - 1.4e-31 107.8 1.6 2.4e-07 30.7 0.1 6.2 1 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ76671.1 - 4.4e-29 97.6 0.2 0.0072 16.4 0.0 9.8 9 0 0 9 9 9 6 Ankyrin repeat Pkinase PF00069.20 EEQ76674.1 - 3.6e-24 85.3 0.0 1.1e-23 83.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ76674.1 - 0.00092 18.3 0.0 0.32 10.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Aconitase PF00330.15 EEQ76676.1 - 1.4e-69 234.8 0.3 3.4e-43 147.7 0.0 2.8 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EEQ76676.1 - 1.1e-23 83.7 0.0 2.2e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Aminotran_5 PF00266.14 EEQ76677.1 - 6.2e-17 61.3 0.0 7.9e-08 31.4 0.0 3.0 2 1 1 3 3 3 3 Aminotransferase class-V HTH_29 PF13551.1 EEQ76677.1 - 0.052 13.7 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn helix NAD_binding_1 PF00175.16 EEQ76678.1 - 1.8e-07 31.7 0.0 5e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EEQ76678.1 - 3e-06 27.2 0.0 4.2e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EEQ76678.1 - 0.0013 18.6 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain AA_permease_2 PF13520.1 EEQ76679.1 - 3e-63 213.8 42.2 4.1e-63 213.3 29.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ76679.1 - 2.5e-26 92.0 28.3 2.5e-26 92.0 19.6 1.9 2 0 0 2 2 2 1 Amino acid permease Methyltransf_26 PF13659.1 EEQ76680.1 - 3.7e-12 46.2 0.0 2e-11 43.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ76680.1 - 1.4e-09 38.4 0.0 2.5e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ76680.1 - 6.8e-08 32.2 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ76680.1 - 0.00024 20.4 0.0 0.001 18.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EEQ76680.1 - 0.00032 21.0 0.0 0.00063 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ76680.1 - 0.0082 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EEQ76680.1 - 0.071 13.5 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ76680.1 - 0.14 12.6 0.0 0.36 11.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain KAR9 PF08580.5 EEQ76680.1 - 3.2 5.9 7.1 4.5 5.4 4.9 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Asp PF00026.18 EEQ76681.1 - 2.2e-68 230.8 0.0 2.7e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EEQ76681.1 - 1e-09 38.5 1.2 1.2e-08 35.1 0.8 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EEQ76681.1 - 8.5e-06 26.1 0.2 0.2 12.1 0.0 3.7 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EEQ76681.1 - 0.00045 19.8 0.0 0.00081 18.9 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Rep_fac_C PF08542.6 EEQ76682.1 - 5.2e-21 74.4 0.1 1.7e-20 72.8 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EEQ76682.1 - 6e-11 42.2 0.0 5.7e-09 35.8 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EEQ76682.1 - 6.9e-11 42.4 0.0 1.1e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EEQ76682.1 - 8.4e-07 28.9 0.0 2e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEQ76682.1 - 4.7e-06 25.8 0.0 1.4e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 EEQ76682.1 - 4.8e-06 25.5 0.0 0.035 12.7 0.0 2.9 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EEQ76682.1 - 9.5e-06 25.7 0.1 0.00054 19.9 0.0 2.7 1 1 2 3 3 3 1 AAA ATPase domain Viral_helicase1 PF01443.13 EEQ76682.1 - 2.8e-05 23.7 0.0 4.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EEQ76682.1 - 2.9e-05 24.1 0.1 0.075 13.1 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_3 PF07726.6 EEQ76682.1 - 0.00022 20.8 0.0 0.00039 20.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EEQ76682.1 - 0.00022 20.7 0.1 0.074 12.4 0.0 2.3 1 1 1 2 2 2 2 AAA-like domain DNA_pol3_delta PF06144.8 EEQ76682.1 - 0.00076 19.0 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_25 PF13481.1 EEQ76682.1 - 0.0015 17.9 0.1 0.13 11.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain DEAD PF00270.24 EEQ76682.1 - 0.002 17.6 0.1 0.13 11.7 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase Mg_chelatase PF01078.16 EEQ76682.1 - 0.0042 16.2 0.0 0.05 12.7 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EEQ76682.1 - 0.0055 16.4 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EEQ76682.1 - 0.006 16.1 0.0 0.0098 15.4 0.0 1.3 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 EEQ76682.1 - 0.012 14.3 0.1 0.031 13.0 0.0 1.6 1 1 1 2 2 2 0 ArgK protein NTPase_1 PF03266.10 EEQ76682.1 - 0.016 14.9 0.3 0.068 12.8 0.1 2.1 1 1 1 2 2 2 0 NTPase AAA_18 PF13238.1 EEQ76682.1 - 0.037 14.3 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EEQ76682.1 - 0.055 12.6 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SAGA-Tad1 PF12767.2 EEQ76682.1 - 0.062 12.9 0.2 0.088 12.4 0.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit FtsK_SpoIIIE PF01580.13 EEQ76682.1 - 0.063 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family NB-ARC PF00931.17 EEQ76682.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DAO PF01266.19 EEQ76683.1 - 1.3e-09 37.4 0.3 5.7e-05 22.1 0.2 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EEQ76683.1 - 7.5e-07 28.5 5.3 0.005 15.9 1.9 3.1 2 1 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 EEQ76683.1 - 2.6e-06 26.3 4.3 0.0068 15.0 0.1 2.1 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.19 EEQ76683.1 - 6.9e-05 21.8 4.3 0.0022 16.9 3.0 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EEQ76683.1 - 0.0027 17.7 1.3 0.0027 17.7 0.9 2.8 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEQ76683.1 - 0.02 14.8 0.1 0.034 14.0 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEQ76683.1 - 0.053 13.9 1.9 0.55 10.6 0.9 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEQ76683.1 - 0.053 13.5 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EEQ76683.1 - 0.07 12.7 1.4 0.12 11.9 1.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EEQ76683.1 - 0.075 11.4 4.2 0.11 10.9 2.1 1.7 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 EEQ76683.1 - 1.1 7.9 3.6 2.1 7.1 2.5 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Polysacc_deac_1 PF01522.16 EEQ76684.1 - 9e-22 77.0 0.0 1.6e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EEQ76684.1 - 0.014 14.7 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) HeH PF12949.2 EEQ76684.1 - 0.15 11.6 0.0 22 4.6 0.0 3.3 3 0 0 3 3 3 0 HeH/LEM domain adh_short PF00106.20 EEQ76685.1 - 5.8e-19 68.6 0.2 6.6e-19 68.4 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ76685.1 - 3.6e-12 46.5 0.0 4.1e-12 46.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ76685.1 - 2.6e-09 37.0 0.2 4.2e-09 36.3 0.1 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EEQ76685.1 - 0.057 12.8 0.0 0.064 12.6 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Amidase PF01425.16 EEQ76686.1 - 1.6e-78 264.5 0.0 1.3e-60 205.5 0.0 2.1 2 0 0 2 2 2 2 Amidase FAD_binding_3 PF01494.14 EEQ76687.1 - 5.5e-63 213.1 0.3 2.8e-61 207.5 0.0 2.0 1 1 1 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.7 EEQ76687.1 - 1.2e-33 116.1 0.0 2.5e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HET PF06985.6 EEQ76688.1 - 4.4e-22 78.7 0.0 8.6e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_11 PF13414.1 EEQ76689.1 - 3.2e-22 77.9 6.8 8e-20 70.2 1.7 2.8 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EEQ76689.1 - 1.1e-15 56.4 5.8 4.6e-06 25.9 0.2 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ76689.1 - 1.5e-12 46.4 8.9 0.00014 21.4 0.3 4.2 4 0 0 4 4 3 3 Tetratricopeptide repeat HeLo PF14479.1 EEQ76689.1 - 4.5e-09 36.3 0.0 9.4e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Prion-inhibition and propagation TPR_16 PF13432.1 EEQ76689.1 - 3.4e-07 30.7 4.7 4.2e-07 30.4 0.9 2.8 2 1 0 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ76689.1 - 2.9e-05 23.9 1.3 0.00033 20.6 0.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ76689.1 - 0.00015 21.2 3.5 0.24 11.2 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ76689.1 - 0.00038 20.3 5.3 0.15 11.9 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ76689.1 - 0.00041 20.7 5.9 0.25 12.1 0.0 4.7 4 1 2 6 6 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ76689.1 - 0.00061 20.0 5.9 0.002 18.4 0.1 3.2 3 1 1 4 4 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EEQ76689.1 - 0.0027 17.8 2.5 0.011 15.8 1.7 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EEQ76689.1 - 0.0094 15.7 1.0 0.023 14.5 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.7 EEQ76689.1 - 0.051 13.3 4.8 0.92 9.3 1.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Ald_Xan_dh_C2 PF02738.13 EEQ76690.1 - 1.3e-178 594.7 0.1 1.8e-178 594.2 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EEQ76690.1 - 5.3e-41 139.8 0.1 9.3e-41 139.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 EEQ76690.1 - 3.3e-36 123.3 0.0 2.5e-35 120.5 0.0 2.4 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 EEQ76690.1 - 3e-25 88.4 0.1 6.6e-25 87.3 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 EEQ76690.1 - 3.5e-11 42.8 0.0 8.4e-10 38.4 0.0 2.7 1 1 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 EEQ76690.1 - 1.7e-06 27.6 0.0 6.5e-06 25.8 0.0 2.0 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain UL11 PF11094.3 EEQ76690.1 - 0.61 9.9 3.5 20 5.0 0.0 2.6 2 0 0 2 2 2 0 Membrane-associated tegument protein Oxidored_FMN PF00724.15 EEQ76691.1 - 1.2e-80 271.0 0.0 2.5e-79 266.7 0.0 2.0 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans PF04082.13 EEQ76692.1 - 7.8e-39 133.1 4.1 7.8e-39 133.1 2.8 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EEQ76692.1 - 3.8e-07 30.0 10.2 0.0062 16.8 1.9 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ76692.1 - 1.6e-06 28.0 10.1 0.00054 20.0 2.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger Herpes_UL32 PF06070.6 EEQ76693.1 - 0.015 13.8 5.8 0.016 13.7 4.0 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DUF410 PF04190.8 EEQ76694.1 - 2e-42 145.5 0.0 2.4e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) DUF3837 PF12939.2 EEQ76694.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) RAI1 PF08652.6 EEQ76695.1 - 4.9e-30 103.1 0.0 9.8e-30 102.1 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease IPPT PF01715.12 EEQ76696.1 - 3.2e-50 170.5 0.5 1.6e-23 83.0 0.0 4.1 3 1 0 3 3 3 3 IPP transferase zf-C2H2_jaz PF12171.3 EEQ76696.1 - 3.1e-06 27.1 0.0 6.2e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_33 PF13671.1 EEQ76696.1 - 3.7e-05 23.6 0.1 0.12 12.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EEQ76696.1 - 7.3e-05 23.5 2.0 0.00012 22.8 0.2 2.5 2 1 0 2 2 1 1 AAA domain zf-met PF12874.2 EEQ76696.1 - 0.00012 22.1 0.1 0.00027 21.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_18 PF13238.1 EEQ76696.1 - 0.0021 18.3 0.2 0.17 12.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain IPT PF01745.11 EEQ76696.1 - 0.0054 15.9 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Isopentenyl transferase zf-C2H2_2 PF12756.2 EEQ76696.1 - 0.013 15.5 0.7 0.029 14.4 0.3 1.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) AAA_28 PF13521.1 EEQ76696.1 - 0.046 13.6 0.5 0.38 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EEQ76696.1 - 0.055 13.6 0.1 0.27 11.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EEQ76696.1 - 0.055 12.8 0.1 0.31 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EEQ76696.1 - 0.14 11.9 0.2 0.51 10.1 0.1 2.0 2 0 0 2 2 2 0 Part of AAA domain BRE1 PF08647.6 EEQ76696.1 - 0.3 11.0 1.6 0.96 9.4 0.2 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase ABC_tran PF00005.22 EEQ76697.1 - 1.8e-15 57.4 0.3 4.1e-14 53.0 0.2 2.2 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EEQ76697.1 - 5.4e-10 39.7 1.0 0.00018 21.5 0.1 2.1 1 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EEQ76697.1 - 5.9e-05 22.2 0.0 0.22 10.5 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EEQ76697.1 - 0.00023 20.4 0.0 0.11 11.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EEQ76697.1 - 0.00033 20.1 0.2 0.00068 19.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EEQ76697.1 - 0.0016 18.4 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.4 EEQ76697.1 - 0.0022 17.4 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF3584 PF12128.3 EEQ76697.1 - 0.0022 15.4 0.3 0.0029 15.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_25 PF13481.1 EEQ76697.1 - 0.0052 16.2 0.3 0.012 15.0 0.2 1.5 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EEQ76697.1 - 0.0095 15.4 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_23 PF13476.1 EEQ76697.1 - 0.011 16.1 0.4 0.016 15.5 0.3 1.2 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EEQ76697.1 - 0.027 14.0 0.2 0.57 9.8 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EEQ76697.1 - 0.03 14.2 0.7 0.057 13.3 0.5 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EEQ76697.1 - 0.036 14.9 1.2 0.11 13.3 0.8 2.1 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EEQ76697.1 - 0.048 12.8 0.0 0.069 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arf PF00025.16 EEQ76697.1 - 0.073 12.3 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family SRP54 PF00448.17 EEQ76697.1 - 0.092 12.1 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Phage_lambd_GpG PF06894.6 EEQ76697.1 - 0.097 12.2 0.0 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 Bacteriophage lambda minor tail protein (GpG) Pr_beta_C PF12465.3 EEQ76697.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Proteasome beta subunits C terminal ATP-synt_ab PF00006.20 EEQ76697.1 - 0.12 11.8 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 EEQ76697.1 - 0.13 11.7 0.1 0.15 11.4 0.1 1.3 1 1 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 EEQ76697.1 - 0.16 11.8 0.2 1.3 8.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 EEQ76697.1 - 0.19 10.1 0.0 0.26 9.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EEQ76697.1 - 0.21 11.6 1.1 0.73 9.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain WD40 PF00400.27 EEQ76698.1 - 7.7e-63 206.3 35.1 2.3e-09 36.7 0.3 12.7 13 0 0 13 13 13 9 WD domain, G-beta repeat BBS2_Mid PF14783.1 EEQ76698.1 - 0.0057 16.4 0.0 23 4.8 0.0 4.8 6 0 0 6 6 6 2 Ciliary BBSome complex subunit 2, middle region Urm1 PF09138.6 EEQ76699.1 - 2.5e-34 117.2 0.0 3e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EEQ76699.1 - 0.0023 18.3 0.0 0.0032 17.8 0.0 1.2 1 0 0 1 1 1 1 ThiS family 6PF2K PF01591.13 EEQ76700.1 - 3e-63 212.8 0.0 4.1e-63 212.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EEQ76700.1 - 1.3e-22 80.5 0.9 2e-22 79.9 0.6 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 EEQ76700.1 - 9.1e-05 23.2 1.1 0.0013 19.5 0.0 2.7 2 2 1 3 3 3 1 AAA domain KTI12 PF08433.5 EEQ76700.1 - 0.0095 15.1 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EEQ76700.1 - 0.0099 15.7 0.0 0.051 13.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 EEQ76700.1 - 0.11 12.1 0.0 2.1 7.9 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase Porin_3 PF01459.17 EEQ76701.1 - 3.7e-82 275.6 0.1 4.3e-82 275.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.5 EEQ76701.1 - 0.0068 15.7 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Pkinase PF00069.20 EEQ76703.1 - 2.8e-64 216.7 0.0 3.5e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ76703.1 - 5.5e-25 87.9 0.0 8.2e-25 87.3 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ76703.1 - 3.5e-07 29.4 0.0 1.6e-06 27.3 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EEQ76703.1 - 0.0016 18.1 0.3 0.012 15.3 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family rpo132 PF12415.3 EEQ76703.1 - 0.017 14.0 0.3 0.18 10.7 0.0 2.3 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase Seadorna_VP7 PF07387.6 EEQ76703.1 - 0.05 12.4 0.0 0.077 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 EEQ76703.1 - 0.056 13.0 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MIF4G_like PF09088.6 EEQ76704.1 - 4.5e-81 270.8 0.1 1.2e-80 269.4 0.0 1.7 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.6 EEQ76704.1 - 1.8e-52 178.1 0.0 2.5e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 MIF4G like DUF4177 PF13783.1 EEQ76704.1 - 0.043 13.4 0.1 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) FA_hydroxylase PF04116.8 EEQ76705.1 - 5.1e-14 52.6 24.9 6.8e-13 49.0 14.3 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily Peptidase_M56 PF05569.6 EEQ76705.1 - 0.052 12.5 0.1 0.084 11.8 0.0 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 WD40 PF00400.27 EEQ76706.1 - 1.1e-72 237.5 11.8 1.7e-12 46.7 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EEQ76706.1 - 4.1e-26 90.9 11.8 6e-26 90.4 8.2 1.2 1 0 0 1 1 1 1 Tup N-terminal Cytochrom_D1 PF02239.11 EEQ76706.1 - 1.6e-06 26.7 1.4 0.00069 18.0 0.1 3.2 1 1 2 3 3 3 2 Cytochrome D1 heme domain eIF2A PF08662.6 EEQ76706.1 - 0.00034 20.3 0.0 0.058 13.1 0.0 3.1 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EEQ76706.1 - 0.0035 15.5 0.3 0.24 9.4 0.0 3.2 1 1 2 3 3 3 1 Nucleoporin Nup120/160 LXG PF04740.7 EEQ76706.1 - 0.017 14.9 1.0 0.026 14.2 0.7 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily Nucleoporin_N PF08801.6 EEQ76706.1 - 0.058 12.1 0.0 1.5 7.5 0.0 3.0 2 1 1 3 3 3 0 Nup133 N terminal like PD40 PF07676.7 EEQ76706.1 - 0.1 12.2 0.5 44 3.8 0.0 4.6 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EEQ76706.1 - 0.14 11.2 0.0 9 5.3 0.0 2.5 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal DUF853 PF05872.7 EEQ76706.1 - 0.17 10.2 0.2 0.23 9.7 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF724 PF05266.9 EEQ76706.1 - 0.35 10.4 3.7 0.54 9.8 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Proteasome_A_N PF10584.4 EEQ76706.1 - 2.2 7.7 3.8 24 4.3 0.0 4.0 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature zf-H2C2_2 PF13465.1 EEQ76710.1 - 2.2e-17 62.3 29.4 3.7e-07 30.1 2.2 5.0 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 EEQ76710.1 - 2.3e-15 55.8 34.5 4e-05 23.6 0.7 5.1 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ76710.1 - 8.8e-14 50.7 23.4 0.0039 17.4 0.2 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 EEQ76710.1 - 0.0048 17.0 9.8 0.12 12.6 0.2 4.1 4 0 0 4 4 4 1 Zinc-finger of C2H2 type Mito_carr PF00153.22 EEQ76711.1 - 1.5e-67 223.3 3.7 3.3e-22 78.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 EEQ76712.1 - 9.4e-35 118.0 0.0 9.2e-17 60.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ76712.1 - 1.2e-19 70.0 0.0 1.3e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ76712.1 - 1.3e-15 56.9 0.0 7.1e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EEQ76712.1 - 0.0046 16.6 0.3 0.46 10.2 0.0 2.2 2 0 0 2 2 2 1 Limkain b1 Cas_Cas2CT1978 PF09707.5 EEQ76712.1 - 0.066 13.1 0.0 5.5 7.0 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) OB_RNB PF08206.6 EEQ76712.1 - 0.15 11.5 0.2 10 5.7 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain Tom7 PF08038.7 EEQ76713.1 - 2.9e-14 52.2 0.3 2.9e-14 52.2 0.2 1.7 2 0 0 2 2 2 1 TOM7 family DUF1385 PF07136.6 EEQ76713.1 - 0.033 13.2 0.0 0.043 12.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) DUF2015 PF09435.5 EEQ76714.1 - 2.2e-46 156.7 0.0 2.5e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.12 EEQ76715.1 - 3.2e-39 133.9 1.4 4.1e-39 133.5 1.0 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_N PF00056.18 EEQ76716.1 - 2.8e-45 153.6 0.1 3.9e-45 153.1 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EEQ76716.1 - 2e-40 138.3 0.0 2.8e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EEQ76716.1 - 8.5e-07 27.9 0.0 1.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EEQ76716.1 - 0.00071 19.6 0.2 0.0012 18.8 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EEQ76716.1 - 0.01 14.9 0.1 0.08 12.0 0.0 2.3 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 EEQ76716.1 - 0.021 14.2 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_hydro_4 PF02056.11 EEQ76716.1 - 0.076 12.3 0.1 3.4 6.9 0.0 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase TRAPP PF04051.11 EEQ76717.1 - 1.8e-36 124.9 0.0 7.6e-36 122.9 0.0 1.8 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component PINIT PF14324.1 EEQ76718.1 - 1.9e-32 112.2 0.1 4.2e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EEQ76718.1 - 1.1e-08 34.4 1.4 2e-08 33.6 1.0 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 EEQ76718.1 - 1.6e-07 30.6 1.4 3e-07 29.7 0.1 2.1 2 0 0 2 2 2 1 SAP domain FAM196 PF15265.1 EEQ76718.1 - 0.022 13.9 0.5 0.036 13.3 0.4 1.3 1 0 0 1 1 1 0 FAM196 family zf-Sec23_Sec24 PF04810.10 EEQ76718.1 - 0.023 14.2 0.2 0.046 13.2 0.1 1.4 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger DUF2423 PF10338.4 EEQ76719.1 - 1.7e-19 69.5 1.4 1.7e-19 69.5 1.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) Phosphodiest PF01663.17 EEQ76720.1 - 2.4e-16 60.0 1.0 3.3e-14 52.9 0.3 2.5 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EEQ76720.1 - 1.1e-05 24.7 0.1 2.7e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 EEQ76720.1 - 0.0015 17.9 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF229 PF02995.12 EEQ76720.1 - 0.25 9.7 0.0 0.37 9.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) SprT-like PF10263.4 EEQ76721.1 - 0.062 12.9 0.3 0.1 12.2 0.2 1.3 1 0 0 1 1 1 0 SprT-like family RRM_1 PF00076.17 EEQ76722.1 - 3.1e-06 26.7 0.1 0.0018 17.8 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ76722.1 - 9e-05 22.2 0.0 0.00036 20.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec15 PF04091.7 EEQ76723.1 - 9.8e-118 392.9 0.5 9.8e-118 392.9 0.3 2.3 2 1 0 3 3 3 1 Exocyst complex subunit Sec15-like Sec5 PF15469.1 EEQ76723.1 - 0.00063 19.5 9.7 0.00092 18.9 2.8 2.8 2 1 0 2 2 2 1 Exocyst complex component Sec5 COG5 PF10392.4 EEQ76723.1 - 0.0016 18.3 7.4 0.0054 16.7 3.3 2.8 2 0 0 2 2 2 1 Golgi transport complex subunit 5 COG7 PF10191.4 EEQ76723.1 - 0.0019 16.1 12.0 0.082 10.8 0.0 2.6 3 0 0 3 3 3 2 Golgi complex component 7 (COG7) DUF2450 PF10475.4 EEQ76723.1 - 0.0098 14.8 7.6 0.025 13.5 5.3 1.6 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 EEQ76723.1 - 0.081 12.7 10.5 0.037 13.9 4.7 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4206 PF13901.1 EEQ76723.1 - 0.11 11.9 0.8 0.28 10.7 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) Sec8_exocyst PF04048.9 EEQ76723.1 - 1.1 8.9 11.4 0.31 10.6 3.7 3.2 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain CBFD_NFYB_HMF PF00808.18 EEQ76724.1 - 4.3e-19 68.3 0.6 6e-19 67.8 0.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEQ76724.1 - 2.2e-12 46.9 0.1 3e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EEQ76724.1 - 0.03 14.1 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Fcf2 PF08698.6 EEQ76725.1 - 1.7e-32 111.3 0.2 4.3e-32 110.0 0.1 1.7 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing Exonuc_VII_L PF02601.10 EEQ76725.1 - 0.8 8.8 4.8 1 8.5 3.3 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit PNP_UDP_1 PF01048.15 EEQ76726.1 - 3.3e-46 157.1 0.1 4.2e-46 156.8 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Ribosomal_S10 PF00338.17 EEQ76727.1 - 1.8e-23 82.1 0.0 4.1e-23 81.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e DUF3579 PF12112.3 EEQ76727.1 - 0.0068 16.2 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3579) tRNA-synt_1b PF00579.20 EEQ76728.1 - 1.6e-68 230.9 0.0 1.9e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) SRPRB PF09439.5 EEQ76729.1 - 1.6e-21 76.3 0.0 1.1e-18 67.0 0.0 3.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EEQ76729.1 - 0.00022 20.5 0.0 0.062 12.5 0.0 2.7 2 1 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EEQ76729.1 - 0.00095 19.1 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EEQ76729.1 - 0.0024 17.8 0.1 0.0087 16.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EEQ76729.1 - 0.014 15.5 0.2 0.071 13.3 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 EEQ76729.1 - 0.021 14.3 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EEQ76729.1 - 0.031 13.8 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 EEQ76729.1 - 0.034 14.6 0.0 2.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_5 PF07728.9 EEQ76729.1 - 0.044 13.4 0.0 0.17 11.6 0.0 2.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEQ76729.1 - 0.058 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EEQ76729.1 - 0.066 13.5 0.0 0.16 12.2 0.0 1.6 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.1 EEQ76729.1 - 0.097 12.9 0.0 0.25 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EEQ76729.1 - 0.099 13.4 0.0 0.18 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EEQ76729.1 - 0.11 12.0 0.1 2.1 7.8 0.0 2.5 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.7 EEQ76729.1 - 0.11 12.1 0.0 2.9 7.5 0.0 2.2 2 0 0 2 2 2 0 NACHT domain DUF258 PF03193.11 EEQ76729.1 - 0.14 11.3 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PALP PF00291.20 EEQ76731.1 - 4.3e-51 173.9 0.1 6e-51 173.4 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EEQ76731.1 - 7.1e-07 28.9 0.0 1.3e-05 24.8 0.0 2.5 2 0 0 2 2 2 1 CBS domain Abhydrolase_6 PF12697.2 EEQ76732.1 - 6.8e-24 85.0 0.0 8.1e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ76732.1 - 1.8e-10 40.7 0.0 4.4e-10 39.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ76732.1 - 6.6e-10 38.9 0.0 4.5e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EEQ76732.1 - 0.0029 17.4 0.0 0.051 13.4 0.0 2.7 2 1 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EEQ76732.1 - 0.0053 16.0 0.0 0.0091 15.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EEQ76732.1 - 0.15 11.4 0.0 0.65 9.3 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Dict-STAT-coil PF09267.5 EEQ76733.1 - 0.4 10.9 12.6 0.82 9.9 0.1 4.0 4 0 0 4 4 4 0 Dictyostelium STAT, coiled coil TipAS PF07739.8 EEQ76733.1 - 1.3 9.3 6.7 2.1 8.6 0.9 3.3 1 1 1 3 3 3 0 TipAS antibiotic-recognition domain Grp1_Fun34_YaaH PF01184.14 EEQ76734.1 - 8.1e-41 139.6 13.7 1.1e-40 139.1 9.5 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3040 PF11239.3 EEQ76734.1 - 0.76 9.8 7.5 2.8 8.0 1.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3040) Grp1_Fun34_YaaH PF01184.14 EEQ76737.1 - 1.6e-87 292.2 18.2 1.9e-87 291.9 12.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ANTH PF07651.11 EEQ76738.1 - 4.3e-58 196.2 0.2 6.7e-58 195.6 0.1 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EEQ76738.1 - 4.8e-11 42.5 0.3 2.8e-10 40.1 0.1 2.1 2 0 0 2 2 2 1 ENTH domain AvrPtoB-E3_ubiq PF09046.5 EEQ76739.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 AvrPtoB E3 ubiquitin ligase Memo PF01875.12 EEQ76740.1 - 4.1e-54 183.3 0.0 5.7e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein Sedlin_N PF04628.8 EEQ76741.1 - 1.1e-23 83.4 0.0 1.6e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EEQ76741.1 - 0.065 12.9 0.1 1.5 8.4 0.0 2.2 1 1 0 1 1 1 0 Sybindin-like family TcpQ PF10671.4 EEQ76741.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q Ank PF00023.25 EEQ76745.1 - 4.3e-06 26.2 0.1 5.5e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 EEQ76745.1 - 5.2e-05 23.5 0.0 7.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEQ76745.1 - 0.00045 20.6 0.1 0.00077 19.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ76745.1 - 0.0085 16.2 0.1 0.017 15.2 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeat Metallophos PF00149.23 EEQ76747.1 - 1.7e-41 141.8 0.4 2.5e-41 141.2 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WD40 PF00400.27 EEQ76748.1 - 6.4e-16 57.5 5.7 5.8e-05 22.8 0.0 5.8 5 1 1 6 6 6 4 WD domain, G-beta repeat HIRA_B PF09453.5 EEQ76748.1 - 0.0014 18.0 0.3 0.0054 16.2 0.2 2.0 1 0 0 1 1 1 1 HIRA B motif eIF2A PF08662.6 EEQ76748.1 - 0.01 15.5 0.1 0.06 13.0 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Cmc1 PF08583.5 EEQ76749.1 - 0.031 14.0 1.8 0.06 13.1 1.2 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like MSA-2c PF12238.3 EEQ76749.1 - 9.6 5.8 10.7 0.82 9.3 0.2 2.3 2 0 0 2 2 2 0 Merozoite surface antigen 2c COG2 PF06148.6 EEQ76750.1 - 2 8.3 5.6 0.99 9.2 1.6 1.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec23_trunk PF04811.10 EEQ76751.1 - 1.7e-81 273.1 0.0 2.7e-81 272.5 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EEQ76751.1 - 8.5e-34 115.0 0.1 1.9e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EEQ76751.1 - 1.8e-30 105.3 0.1 3.6e-30 104.3 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EEQ76751.1 - 6.4e-16 57.6 4.5 1.3e-15 56.6 3.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EEQ76751.1 - 5.5e-11 42.0 0.0 1.4e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat DNA_primase_lrg PF04104.9 EEQ76752.1 - 4e-81 272.1 0.0 5.3e-81 271.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit ADK PF00406.17 EEQ76753.1 - 1.8e-36 125.3 0.0 3.3e-20 72.4 0.0 2.0 1 1 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 EEQ76753.1 - 2.1e-15 56.0 0.0 3.9e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EEQ76753.1 - 0.00019 22.2 0.0 0.00044 21.0 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEQ76753.1 - 0.00042 20.6 0.0 0.0029 17.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEQ76753.1 - 0.0012 18.7 0.0 0.0036 17.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 EEQ76753.1 - 0.055 12.2 0.0 0.075 11.7 0.0 1.2 1 0 0 1 1 1 0 ArgK protein SNase PF00565.12 EEQ76754.1 - 2.1e-05 24.7 0.0 3.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue EVI2A PF05399.6 EEQ76754.1 - 0.6 9.3 4.2 0.87 8.7 2.9 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Ribosomal_L11_N PF03946.9 EEQ76755.1 - 2.1e-17 62.3 0.1 3.1e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EEQ76755.1 - 1.5e-09 37.8 0.1 2.3e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Mito_carr PF00153.22 EEQ76756.1 - 4.7e-55 183.2 0.5 1.3e-19 69.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 EEQ76758.1 - 4.3e-38 128.7 0.0 1.6e-11 43.6 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ76758.1 - 3.3e-37 126.3 0.0 2.5e-09 36.9 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ76758.1 - 3.1e-17 62.1 0.0 0.00014 21.5 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 EEQ76758.1 - 1.7e-12 46.7 4.8 1.7e-12 46.7 3.3 2.4 2 0 0 2 2 2 1 Putative RRM domain RRM_3 PF08777.6 EEQ76758.1 - 3.7e-05 23.5 0.1 0.061 13.1 0.0 2.7 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 EEQ76758.1 - 0.0076 16.0 0.0 6.4 6.6 0.0 3.2 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif DUF4523 PF15023.1 EEQ76758.1 - 0.027 13.9 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) RNA_bind PF08675.6 EEQ76758.1 - 0.028 14.3 0.0 0.21 11.6 0.0 2.4 2 0 0 2 2 2 0 RNA binding domain DUF1762 PF08574.5 EEQ76759.1 - 1.7e-16 60.3 6.4 1.7e-16 60.3 4.5 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF1762) DUF3763 PF12592.3 EEQ76761.1 - 0.2 11.3 0.1 0.2 11.3 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3763) tRNA-synt_2 PF00152.15 EEQ76765.1 - 3e-75 253.0 0.4 4.8e-75 252.3 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EEQ76765.1 - 2.5e-08 33.6 0.0 4.8e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1565 PF07602.6 EEQ76765.1 - 0.19 10.8 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) MT-A70 PF05063.9 EEQ76766.1 - 6.5e-22 77.9 0.4 9.4e-21 74.1 0.3 2.2 1 1 0 1 1 1 1 MT-A70 DUF4525 PF15027.1 EEQ76766.1 - 0.035 13.6 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) CRM1_C PF08767.6 EEQ76768.1 - 1.6e-113 378.8 7.6 1.6e-113 378.8 5.2 2.7 2 1 1 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 EEQ76768.1 - 7.2e-38 129.8 11.5 4.7e-36 123.9 3.2 4.9 5 1 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 EEQ76768.1 - 4.5e-10 39.2 0.0 2.4e-09 36.9 0.0 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain uDENN PF03456.13 EEQ76768.1 - 0.0051 16.7 0.0 0.026 14.4 0.0 2.1 2 0 0 2 2 2 1 uDENN domain Vac14_Fab1_bd PF12755.2 EEQ76768.1 - 0.018 15.4 2.0 8.5 6.8 0.0 4.4 5 1 0 5 5 5 0 Vacuolar 14 Fab1-binding region CitG PF01874.11 EEQ76768.1 - 0.055 12.6 0.0 11 5.0 0.0 3.2 4 0 0 4 4 4 0 ATP:dephospho-CoA triphosphoribosyl transferase Mac PF12464.3 EEQ76769.1 - 3.1e-14 52.7 0.5 6.4e-14 51.7 0.4 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 EEQ76769.1 - 7.6e-13 47.3 6.5 1.7e-07 30.4 0.3 3.4 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Zn_clus PF00172.13 EEQ76769.1 - 5.1e-09 35.8 8.5 9.1e-09 35.0 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep_2 PF14602.1 EEQ76769.1 - 5.7e-09 35.3 6.3 8.5e-07 28.4 0.1 3.1 2 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase ALAD PF00490.16 EEQ76772.1 - 8.8e-118 392.8 0.0 1e-117 392.6 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase CIAPIN1 PF05093.8 EEQ76774.1 - 1.6e-33 114.7 2.9 1.6e-33 114.7 2.0 1.8 2 0 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis SPT6_acidic PF14632.1 EEQ76774.1 - 0.14 12.3 0.2 0.14 12.3 0.1 2.1 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Sporozoite_P67 PF05642.6 EEQ76774.1 - 1.2 6.8 6.9 2.1 6.0 4.5 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen NEL PF14496.1 EEQ76775.1 - 0.042 13.1 0.1 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 C-terminal novel E3 ligase, LRR-interacting APH PF01636.18 EEQ76776.1 - 1.5e-06 28.1 0.1 0.0001 22.1 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF1679 PF07914.6 EEQ76776.1 - 0.17 10.4 0.0 0.25 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) HABP4_PAI-RBP1 PF04774.10 EEQ76777.1 - 0.0025 18.2 2.3 0.0032 17.9 1.5 1.4 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family Nucleoporin_C PF03177.9 EEQ76778.1 - 1.6e-128 429.8 2.3 1.9e-128 429.5 1.6 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EEQ76778.1 - 1.8e-47 162.0 0.0 2.6e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like UCH PF00443.24 EEQ76779.1 - 1.8e-43 148.5 0.0 2.9e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EEQ76779.1 - 6.6e-23 80.5 11.7 1.8e-19 69.6 0.5 3.1 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 EEQ76779.1 - 9.6e-23 79.3 0.4 1.2e-10 40.8 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 EEQ76779.1 - 2.5e-19 69.8 0.1 1.7e-14 53.9 0.0 3.7 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.1 EEQ76779.1 - 0.1 12.1 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain Rep_fac-A_C PF08646.5 EEQ76780.1 - 1.8e-58 196.3 10.2 2e-55 186.5 3.0 2.6 3 0 0 3 3 3 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EEQ76780.1 - 4.1e-23 81.0 0.0 9.5e-23 79.9 0.0 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EEQ76780.1 - 2e-15 56.3 0.1 3.8e-10 39.4 0.0 4.1 4 0 0 4 4 4 3 OB-fold nucleic acid binding domain ADH_zinc_N PF00107.21 EEQ76781.1 - 3.5e-23 81.5 0.0 6.4e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEQ76781.1 - 4.5e-16 59.9 0.0 1e-15 58.7 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEQ76781.1 - 9.5e-10 38.2 0.0 3.1e-09 36.5 0.0 1.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DEAD PF00270.24 EEQ76782.1 - 2e-45 154.3 0.0 2.9e-44 150.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ76782.1 - 2.7e-26 91.2 0.0 2.1e-25 88.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ76782.1 - 3.6e-06 26.9 0.0 7.5e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EEQ76782.1 - 0.0096 15.0 0.1 0.0096 15.0 0.1 2.2 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 EEQ76782.1 - 0.026 12.9 0.0 1.3 7.3 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1253) Rft-1 PF04506.8 EEQ76783.1 - 5.9e-91 305.5 5.8 7.1e-91 305.2 4.0 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.12 EEQ76783.1 - 0.11 11.7 13.3 0.31 10.2 0.1 3.2 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein OST3_OST6 PF04756.8 EEQ76784.1 - 6.5e-22 77.8 3.4 6.5e-22 77.8 2.4 1.4 2 0 0 2 2 2 1 OST3 / OST6 family Thioredoxin PF00085.15 EEQ76784.1 - 0.061 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin DUF1129 PF06570.6 EEQ76784.1 - 0.24 10.6 5.0 2 7.6 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Reo_sigmaC PF04582.7 EEQ76785.1 - 8.4e-06 25.1 6.5 1.5e-05 24.3 4.5 1.3 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Spc7 PF08317.6 EEQ76785.1 - 0.0024 16.5 7.1 0.0024 16.5 4.9 2.4 1 1 1 2 2 2 1 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 EEQ76785.1 - 0.01 15.6 9.2 0.01 15.6 6.4 3.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3037 PF11236.3 EEQ76785.1 - 0.086 12.8 2.7 1.8 8.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) DUF3450 PF11932.3 EEQ76785.1 - 0.27 10.4 18.0 0.015 14.6 3.9 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) M_domain PF12938.2 EEQ76785.1 - 1 9.1 9.6 22 4.7 5.5 2.9 1 1 1 2 2 2 0 M domain of GW182 Baculo_PEP_C PF04513.7 EEQ76785.1 - 1.2 8.9 9.5 0.3 10.8 0.6 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF641 PF04859.7 EEQ76785.1 - 3 7.5 22.4 0.077 12.7 0.7 3.7 1 1 2 4 4 4 0 Plant protein of unknown function (DUF641) Kinesin-related PF06548.6 EEQ76785.1 - 4.5 5.7 36.6 0.045 12.3 12.6 3.1 2 1 1 3 3 3 0 Kinesin-related FtsJ PF01728.14 EEQ76786.1 - 7.4e-64 215.0 0.0 9.1e-64 214.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 EEQ76786.1 - 4.4e-06 26.4 0.0 9.5e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ76786.1 - 0.00017 22.1 0.0 0.00039 20.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ76786.1 - 0.00031 20.3 0.0 0.46 10.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ76786.1 - 0.0033 17.8 0.1 1.4 9.4 0.0 2.7 1 1 0 2 2 2 2 Methyltransferase domain ThiF PF00899.16 EEQ76787.1 - 3.5e-27 94.8 0.0 5.4e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EEQ76787.1 - 0.00086 19.4 0.0 0.0026 17.8 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EEQ76787.1 - 0.095 11.8 0.0 0.35 9.9 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain dCMP_cyt_deam_1 PF00383.17 EEQ76788.1 - 1.1e-26 92.4 1.6 1.5e-26 92.0 1.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region CoaE PF01121.15 EEQ76788.1 - 0.0058 16.0 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 EEQ76788.1 - 0.0076 16.5 0.0 0.026 14.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEQ76788.1 - 0.049 13.4 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain PSD5 PF07637.6 EEQ76788.1 - 0.069 13.1 0.2 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1595) AAA_17 PF13207.1 EEQ76788.1 - 0.091 13.5 0.1 0.2 12.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain CobU PF02283.11 EEQ76788.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase His_biosynth PF00977.16 EEQ76789.1 - 9.8e-48 162.4 0.7 3.6e-47 160.5 0.5 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EEQ76789.1 - 1.2e-29 103.2 0.0 1.9e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 EEQ76789.1 - 1.6e-11 44.2 0.0 1.7e-10 40.8 0.0 2.2 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EEQ76789.1 - 2.7e-09 36.8 0.0 5.7e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 EEQ76789.1 - 0.0083 15.5 0.1 0.04 13.3 0.1 2.0 1 1 0 1 1 1 1 Peptidase C26 DWNN PF08783.6 EEQ76790.1 - 4.5e-33 113.0 0.1 8.1e-33 112.1 0.1 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 EEQ76790.1 - 5.9e-06 25.6 7.3 1.8e-05 24.0 5.1 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EEQ76790.1 - 0.019 14.8 1.2 0.019 14.8 0.8 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-C3HC4 PF00097.20 EEQ76790.1 - 1.2 8.8 9.3 2.8 7.6 6.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EEQ76790.1 - 1.9 8.4 10.1 5.4 6.9 7.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EEQ76790.1 - 7.9 6.6 16.0 0.24 11.4 5.9 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ATG22 PF11700.3 EEQ76791.1 - 6e-194 644.9 15.7 4.7e-191 635.4 10.9 2.0 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EEQ76791.1 - 0.00039 19.2 4.7 0.00039 19.2 3.2 3.2 2 1 0 3 3 3 2 Major Facilitator Superfamily APH PF01636.18 EEQ76792.1 - 4.7e-09 36.3 0.1 1.2e-07 31.7 0.2 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family MgtE PF01769.11 EEQ76794.1 - 0.0088 16.3 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 Divalent cation transporter SPX PF03105.14 EEQ76795.1 - 2.3e-44 152.2 0.0 3.6e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EEQ76795.1 - 5.1e-29 101.4 41.2 7.1e-29 100.9 28.6 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EEQ76795.1 - 4.6e-14 51.7 28.8 4.6e-14 51.7 20.0 2.9 1 1 2 3 3 3 3 Citrate transporter Peptidase_S28 PF05577.7 EEQ76796.1 - 1.7e-49 168.5 0.0 3.1e-36 124.9 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 EEQ76796.1 - 0.00087 19.2 0.0 0.018 14.9 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family bZIP_1 PF00170.16 EEQ76797.1 - 1e-08 35.0 3.2 1.2e-08 34.7 2.2 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEQ76797.1 - 9.3e-06 25.3 6.5 1.4e-05 24.8 4.5 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EEQ76797.1 - 0.029 14.6 2.1 0.041 14.1 1.4 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor CAF-1_p150 PF11600.3 EEQ76797.1 - 0.056 12.8 3.3 0.07 12.5 2.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MCC-bdg_PDZ PF10506.4 EEQ76797.1 - 0.071 12.9 2.5 2.4 8.0 0.1 2.1 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome PAT1 PF09770.4 EEQ76797.1 - 2.4 6.3 6.6 2.5 6.2 4.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_S7 PF00177.16 EEQ76798.1 - 1.1e-26 93.2 0.2 2.5e-26 92.0 0.1 1.7 1 1 0 1 1 1 1 Ribosomal protein S7p/S5e Na_Ca_ex PF01699.19 EEQ76799.1 - 1.1e-45 154.6 35.3 7.2e-24 83.9 8.2 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Glycoprotein_G PF00802.14 EEQ76799.1 - 0.042 12.9 0.3 0.072 12.2 0.2 1.3 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G TIL PF01826.12 EEQ76800.1 - 0.019 15.0 1.5 0.026 14.6 1.0 1.2 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain AroM PF07302.6 EEQ76804.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 AroM protein Glyco_hydro_81 PF03639.8 EEQ76808.1 - 7.3e-199 662.1 0.1 8.8e-199 661.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Utp14 PF04615.8 EEQ76809.1 - 5.1e-215 715.9 64.5 5.1e-215 715.9 44.7 2.0 1 1 1 2 2 2 1 Utp14 protein TRSP PF12500.3 EEQ76809.1 - 0.0076 15.7 0.8 0.025 14.0 0.5 1.8 1 0 0 1 1 1 1 TRSP domain C terminus to PRTase_2 MRP-L27 PF09809.4 EEQ76810.1 - 2.3e-12 46.4 0.1 3.1e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 HECT PF00632.20 EEQ76811.1 - 1.7e-81 273.8 0.0 2.6e-81 273.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 EEQ76811.1 - 0.003 17.0 2.4 0.009 15.5 1.7 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif NAGLU PF05089.7 EEQ76813.1 - 3.2e-118 394.2 5.6 4.1e-118 393.9 3.9 1.1 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 EEQ76813.1 - 1.5e-60 204.9 0.1 2.3e-60 204.2 0.1 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 EEQ76813.1 - 3.8e-16 58.5 0.0 1.1e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain RRM_1 PF00076.17 EEQ76814.1 - 4.8e-80 263.1 9.5 4.6e-23 80.6 0.4 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ76814.1 - 4.2e-53 177.2 2.4 1.8e-15 56.6 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ76814.1 - 2.7e-37 126.3 1.3 8.6e-09 35.1 0.0 5.1 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EEQ76814.1 - 6.6e-31 105.8 0.8 6.6e-31 105.8 0.5 2.6 4 0 0 4 4 4 1 Poly-adenylate binding protein, unique domain CbiG_mid PF11761.3 EEQ76814.1 - 3.9e-05 23.7 0.1 1.1 9.5 0.0 3.7 3 0 0 3 3 3 2 Cobalamin biosynthesis central region Limkain-b1 PF11608.3 EEQ76814.1 - 0.00028 20.5 3.4 5.2 6.8 0.2 4.0 2 1 1 3 3 3 3 Limkain b1 Nup35_RRM_2 PF14605.1 EEQ76814.1 - 0.0046 16.7 0.1 14 5.5 0.0 4.0 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.6 EEQ76814.1 - 0.37 10.3 4.0 8.4 5.9 0.0 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain Fe-ADH PF00465.14 EEQ76815.1 - 1.6e-46 158.6 0.7 5.4e-27 94.3 2.5 2.1 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EEQ76815.1 - 6.6e-10 38.7 1.8 7.6e-10 38.5 0.0 2.0 3 0 0 3 3 3 1 Iron-containing alcohol dehydrogenase DAO PF01266.19 EEQ76816.1 - 9.9e-55 185.8 2.0 1.1e-54 185.6 1.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEQ76816.1 - 0.0008 19.3 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EEQ76816.1 - 0.019 15.0 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEQ76816.1 - 0.044 13.6 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EEQ76816.1 - 0.1 11.4 0.1 0.71 8.7 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Mqo PF06039.10 EEQ76816.1 - 0.14 10.3 0.0 1.8 6.6 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Vps52 PF04129.7 EEQ76817.1 - 2.5e-113 379.3 0.0 7.6e-113 377.7 0.0 1.6 1 1 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 EEQ76817.1 - 2.1e-06 26.2 0.9 3.4e-06 25.5 0.1 1.7 2 0 0 2 2 2 1 Exocyst complex component Sec3 IFT57 PF10498.4 EEQ76817.1 - 0.022 13.5 0.2 0.056 12.1 0.1 1.7 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 IncA PF04156.9 EEQ76817.1 - 0.23 11.0 2.7 0.16 11.5 0.3 1.8 2 0 0 2 2 2 0 IncA protein eIF-5a PF01287.15 EEQ76818.1 - 1.1e-25 89.3 1.2 1.5e-25 88.9 0.9 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EEQ76818.1 - 2.2e-05 23.9 0.5 4.4e-05 23.0 0.4 1.5 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EEQ76818.1 - 0.0038 17.0 0.2 0.048 13.5 0.0 2.4 3 0 0 3 3 3 1 Elongation factor P (EF-P) KOW-like domain Response_reg PF00072.19 EEQ76818.1 - 0.13 12.2 0.1 0.19 11.7 0.1 1.5 1 1 0 1 1 1 0 Response regulator receiver domain RRN7 PF11781.3 EEQ76819.1 - 0.00069 19.0 2.5 0.0015 18.0 1.7 1.6 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 ubiquitin PF00240.18 EEQ76820.1 - 2.8e-34 116.3 0.9 4.1e-34 115.7 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EEQ76820.1 - 1.3e-30 104.7 11.0 2.5e-30 103.8 7.6 1.5 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EEQ76820.1 - 6.2e-18 64.2 0.3 9.9e-18 63.6 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EEQ76820.1 - 2.1e-05 24.7 0.1 7.4e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EEQ76820.1 - 0.0037 16.9 0.0 0.006 16.2 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EEQ76820.1 - 0.017 15.0 0.0 0.041 13.7 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EEQ76820.1 - 0.022 14.9 0.1 0.029 14.5 0.0 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Plexin_cytopl PF08337.7 EEQ76820.1 - 0.084 11.1 0.1 1.2 7.3 0.1 2.0 2 0 0 2 2 2 0 Plexin cytoplasmic RasGAP domain Yip1 PF04893.12 EEQ76821.1 - 2.1e-16 59.9 12.4 3.1e-16 59.3 8.6 1.3 1 1 0 1 1 1 1 Yip1 domain CopD PF05425.8 EEQ76821.1 - 0.004 17.3 5.6 0.27 11.4 0.2 2.3 2 0 0 2 2 2 2 Copper resistance protein D RabGAP-TBC PF00566.13 EEQ76822.1 - 2.6e-26 92.4 0.1 3.6e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MMS1_N PF10433.4 EEQ76823.1 - 1.4e-139 465.5 0.0 2.2e-139 464.8 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term GTP_EFTU PF00009.22 EEQ76824.1 - 1.8e-31 109.0 0.0 8.6e-31 106.8 0.0 2.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EEQ76824.1 - 5.8e-19 67.9 0.1 1.5e-18 66.6 0.1 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EEQ76824.1 - 1.2e-11 44.5 2.9 9.7e-10 38.4 0.0 3.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEQ76824.1 - 7.8e-06 25.8 0.1 3.1e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EEQ76824.1 - 0.00045 20.6 0.0 0.0024 18.3 0.0 2.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D4 PF14578.1 EEQ76824.1 - 0.015 14.9 0.1 0.069 12.7 0.1 2.2 1 1 0 1 1 1 0 Elongation factor Tu domain 4 Rhodanese PF00581.15 EEQ76825.1 - 1.2e-09 38.5 0.0 5.4e-09 36.3 0.0 2.1 2 1 0 2 2 2 1 Rhodanese-like domain p450 PF00067.17 EEQ76826.1 - 3.7e-57 193.8 0.0 5.3e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PPR_3 PF13812.1 EEQ76828.1 - 4.2e-19 67.1 4.7 3.6e-05 23.7 0.0 8.6 9 0 0 9 9 9 4 Pentatricopeptide repeat domain PPR_2 PF13041.1 EEQ76828.1 - 3.1e-17 62.2 0.0 1.4e-08 34.5 0.0 4.8 4 1 1 5 5 5 3 PPR repeat family PPR PF01535.15 EEQ76828.1 - 1.5e-10 40.3 3.6 0.011 15.6 0.0 7.9 9 0 0 9 9 9 1 PPR repeat TPR_16 PF13432.1 EEQ76828.1 - 0.00011 22.8 0.7 1.1 9.9 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat PPR_1 PF12854.2 EEQ76828.1 - 0.0014 18.0 0.0 16 5.1 0.0 4.5 4 0 0 4 4 4 1 PPR repeat MCM PF00493.18 EEQ76829.1 - 3.6e-130 433.6 0.2 5.8e-130 432.9 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EEQ76829.1 - 3.2e-17 63.1 0.0 9e-17 61.6 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEQ76829.1 - 1e-06 28.0 0.0 1.3e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EEQ76829.1 - 0.0035 16.9 0.0 0.0081 15.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RAP1 PF07218.6 EEQ76829.1 - 3.3 5.6 8.9 5 5.1 6.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Spo7 PF03907.8 EEQ76830.1 - 1.2e-66 224.3 0.0 1.7e-66 223.7 0.0 1.2 1 0 0 1 1 1 1 Spo7-like protein Menin PF05053.8 EEQ76830.1 - 3.8 5.5 6.2 5.3 5.0 4.3 1.1 1 0 0 1 1 1 0 Menin Abhydrolase_6 PF12697.2 EEQ76831.1 - 2.1e-28 99.7 0.4 3.2e-27 95.8 0.3 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ76831.1 - 5.8e-16 58.7 0.0 7.6e-15 55.0 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ76831.1 - 1.3e-13 50.9 0.0 7.1e-11 42.0 0.0 2.8 2 1 0 3 3 3 1 Alpha/beta hydrolase family Esterase PF00756.15 EEQ76831.1 - 0.00023 20.6 0.0 0.00049 19.5 0.0 1.5 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.6 EEQ76831.1 - 0.00048 19.2 0.0 0.00094 18.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.3 EEQ76831.1 - 0.00085 19.1 0.0 0.0027 17.5 0.0 1.8 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 EEQ76831.1 - 0.0024 16.7 0.0 0.0044 15.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.20 EEQ76831.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2305 PF10230.4 EEQ76831.1 - 0.02 14.3 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_3 PF07859.8 EEQ76831.1 - 0.034 13.7 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EEQ76831.1 - 0.041 13.3 0.0 11 5.3 0.0 2.7 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Thioesterase PF00975.15 EEQ76831.1 - 0.054 13.7 3.1 0.27 11.4 0.3 2.9 2 1 0 2 2 2 0 Thioesterase domain Pex14_N PF04695.8 EEQ76831.1 - 6 6.9 15.4 0.69 9.9 4.7 3.0 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RAP1 PF07218.6 EEQ76831.1 - 9.4 4.1 5.3 14 3.5 3.7 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Competence PF03772.11 EEQ76832.1 - 0.0013 17.9 4.4 0.0017 17.4 3.0 1.1 1 0 0 1 1 1 1 Competence protein TatD_DNase PF01026.16 EEQ76833.1 - 4.2e-32 111.3 0.0 6.8e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase TPP_enzyme_N PF02776.13 EEQ76835.1 - 2.3e-39 134.6 0.2 1.4e-38 132.1 0.0 2.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EEQ76835.1 - 2.1e-22 79.3 0.0 9.2e-22 77.2 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EEQ76835.1 - 6.2e-20 71.3 0.0 1.1e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF4248 PF14053.1 EEQ76835.1 - 0.015 14.8 0.2 0.037 13.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) PLDc_2 PF13091.1 EEQ76837.1 - 9.8e-18 64.1 0.2 8e-09 35.3 0.1 2.2 2 0 0 2 2 2 2 PLD-like domain Regulator_TrmB PF11495.3 EEQ76837.1 - 0.0027 16.7 0.0 0.59 9.0 0.0 2.3 2 0 0 2 2 2 2 Archaeal transcriptional regulator TrmB PLDc PF00614.17 EEQ76837.1 - 0.0032 17.2 0.2 0.23 11.3 0.0 2.5 2 0 0 2 2 2 1 Phospholipase D Active site motif DUF1564 PF07600.6 EEQ76838.1 - 0.048 13.0 3.8 0.067 12.5 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) DUF3074 PF11274.3 EEQ76838.1 - 0.11 12.0 2.7 0.13 11.8 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) Thioredoxin_2 PF13098.1 EEQ76838.1 - 0.95 9.6 5.0 2.1 8.5 3.5 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain Tnp_zf-ribbon_2 PF13842.1 EEQ76838.1 - 1.6 9.1 5.1 3.4 8.1 3.5 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon ADIP PF11559.3 EEQ76839.1 - 2.6e-05 24.1 2.5 3.7e-05 23.6 1.7 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DivIC PF04977.10 EEQ76839.1 - 4.4e-05 22.8 8.4 0.0021 17.5 1.1 2.1 1 1 1 2 2 2 2 Septum formation initiator CENP-F_leu_zip PF10473.4 EEQ76839.1 - 0.00013 21.7 1.4 0.00019 21.3 1.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EEQ76839.1 - 0.00035 20.2 3.2 0.00047 19.8 2.2 1.1 1 0 0 1 1 1 1 IncA protein Spc24 PF08286.6 EEQ76839.1 - 0.00056 19.5 0.9 0.00082 19.0 0.6 1.2 1 0 0 1 1 1 1 Spc24 subunit of Ndc80 DUF3450 PF11932.3 EEQ76839.1 - 0.00077 18.8 3.0 0.0011 18.3 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) ALIX_LYPXL_bnd PF13949.1 EEQ76839.1 - 0.0011 17.9 0.1 0.0015 17.5 0.1 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV HOOK PF05622.7 EEQ76839.1 - 0.0013 16.6 0.5 0.0016 16.3 0.4 1.0 1 0 0 1 1 1 1 HOOK protein TMF_TATA_bd PF12325.3 EEQ76839.1 - 0.0016 18.1 0.8 0.0023 17.6 0.6 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF904 PF06005.7 EEQ76839.1 - 0.0018 18.5 5.5 0.0033 17.6 3.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF904) DUF4515 PF14988.1 EEQ76839.1 - 0.0019 17.9 3.5 0.0028 17.3 2.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) ATG16 PF08614.6 EEQ76839.1 - 0.0022 17.8 0.3 0.0025 17.6 0.2 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Filament PF00038.16 EEQ76839.1 - 0.003 17.0 1.4 0.0041 16.6 1.0 1.1 1 0 0 1 1 1 1 Intermediate filament protein TBPIP PF07106.8 EEQ76839.1 - 0.003 17.1 1.8 0.0047 16.4 1.2 1.3 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) BLOC1_2 PF10046.4 EEQ76839.1 - 0.0031 17.6 3.6 0.0048 17.0 2.5 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Jnk-SapK_ap_N PF09744.4 EEQ76839.1 - 0.0036 17.3 2.5 0.0048 16.9 1.7 1.1 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 DUF812 PF05667.6 EEQ76839.1 - 0.0046 15.5 0.1 0.0049 15.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) FlaC_arch PF05377.6 EEQ76839.1 - 0.0046 16.8 3.3 0.0085 15.9 2.3 1.5 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) DUF972 PF06156.8 EEQ76839.1 - 0.0061 16.8 1.2 0.0098 16.2 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF972) Striatin PF08232.7 EEQ76839.1 - 0.0061 16.8 1.8 0.011 16.1 1.2 1.4 1 0 0 1 1 1 1 Striatin family HALZ PF02183.13 EEQ76839.1 - 0.0065 16.1 10.3 0.14 11.8 1.4 2.4 1 1 1 2 2 2 2 Homeobox associated leucine zipper PspA_IM30 PF04012.7 EEQ76839.1 - 0.007 15.7 1.7 0.0092 15.3 1.2 1.1 1 0 0 1 1 1 1 PspA/IM30 family DUF2353 PF09789.4 EEQ76839.1 - 0.0084 15.3 0.0 0.0096 15.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) APG6 PF04111.7 EEQ76839.1 - 0.0086 15.1 0.6 0.0088 15.1 0.5 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 V_ATPase_I PF01496.14 EEQ76839.1 - 0.01 13.7 0.3 0.011 13.6 0.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 EEQ76839.1 - 0.011 14.7 0.1 0.013 14.5 0.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 MCC-bdg_PDZ PF10506.4 EEQ76839.1 - 0.012 15.4 4.9 4.2 7.2 0.0 2.5 2 1 1 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Herpes_UL6 PF01763.11 EEQ76839.1 - 0.012 13.7 0.1 0.012 13.7 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like TPR_MLP1_2 PF07926.7 EEQ76839.1 - 0.028 14.1 3.9 0.049 13.3 2.7 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Macoilin PF09726.4 EEQ76839.1 - 0.029 12.6 0.0 0.03 12.6 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF2205 PF10224.4 EEQ76839.1 - 0.03 13.8 2.7 0.084 12.4 1.9 1.6 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Bap31 PF05529.7 EEQ76839.1 - 0.031 13.7 0.2 0.037 13.4 0.1 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF3138 PF11336.3 EEQ76839.1 - 0.035 12.3 0.1 0.083 11.0 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) DUF641 PF04859.7 EEQ76839.1 - 0.036 13.8 0.2 0.049 13.3 0.2 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Laminin_II PF06009.7 EEQ76839.1 - 0.042 13.6 0.2 0.06 13.0 0.1 1.2 1 0 0 1 1 1 0 Laminin Domain II DUF4140 PF13600.1 EEQ76839.1 - 0.05 14.0 0.2 0.076 13.4 0.2 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) NTR2 PF15458.1 EEQ76839.1 - 0.05 12.8 2.4 0.065 12.4 1.7 1.2 1 0 0 1 1 1 0 Nineteen complex-related protein 2 bZIP_1 PF00170.16 EEQ76839.1 - 0.051 13.5 7.3 0.15 12.0 5.0 1.8 1 1 0 1 1 1 0 bZIP transcription factor Tnp_P_element PF12017.3 EEQ76839.1 - 0.068 12.4 0.2 0.096 11.8 0.1 1.2 1 0 0 1 1 1 0 Transposase protein RTBV_P46 PF06216.6 EEQ76839.1 - 0.074 11.8 0.6 0.097 11.5 0.4 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein DUF3373 PF11853.3 EEQ76839.1 - 0.081 11.4 2.5 0.11 11.0 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) IFP_35_N PF07334.8 EEQ76839.1 - 0.086 12.8 14.4 0.51 10.3 3.0 3.2 1 1 2 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF2730 PF10805.3 EEQ76839.1 - 0.1 12.3 1.8 0.16 11.6 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) bZIP_2 PF07716.10 EEQ76839.1 - 0.1 12.4 15.9 0.56 10.0 3.3 2.5 2 1 1 3 3 2 0 Basic region leucine zipper TSC22 PF01166.13 EEQ76839.1 - 0.11 12.5 5.0 0.26 11.2 1.3 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family Nsp1_C PF05064.8 EEQ76839.1 - 0.12 12.0 5.5 0.23 11.1 3.8 1.5 1 0 0 1 1 1 0 Nsp1-like C-terminal region AKNA PF12443.3 EEQ76839.1 - 0.17 11.8 4.5 0.44 10.5 3.0 1.8 1 1 1 2 2 2 0 AT-hook-containing transcription factor DUF2968 PF11180.3 EEQ76839.1 - 0.2 11.0 3.3 0.28 10.5 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DASH_Dad3 PF08656.5 EEQ76839.1 - 0.22 11.2 5.2 0.93 9.2 3.6 2.0 1 1 0 1 1 1 0 DASH complex subunit Dad3 Prefoldin_2 PF01920.15 EEQ76839.1 - 0.3 10.8 11.4 0.064 13.0 1.9 2.1 1 1 1 2 2 2 0 Prefoldin subunit Rab5-bind PF09311.6 EEQ76839.1 - 0.34 10.7 8.1 0.58 10.0 5.6 1.3 1 0 0 1 1 1 0 Rabaptin-like protein DMPK_coil PF08826.5 EEQ76839.1 - 0.38 10.6 8.1 2.4 8.1 0.8 2.5 1 1 1 2 2 2 0 DMPK coiled coil domain like RBD-FIP PF09457.5 EEQ76839.1 - 0.42 10.4 10.1 0.097 12.4 1.8 2.2 1 1 1 2 2 2 0 FIP domain TMF_DNA_bd PF12329.3 EEQ76839.1 - 0.62 9.9 8.3 1.2 9.0 5.8 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Ribosomal_L29 PF00831.18 EEQ76839.1 - 0.84 9.3 10.4 1.6 8.4 1.3 2.4 1 1 1 2 2 2 0 Ribosomal L29 protein TPD52 PF04201.10 EEQ76839.1 - 0.96 9.1 5.5 2.2 7.9 3.8 1.6 1 1 0 1 1 1 0 Tumour protein D52 family DivIVA PF05103.8 EEQ76839.1 - 1.1 9.2 7.4 3 7.9 0.7 1.8 1 1 1 2 2 2 0 DivIVA protein Herpes_BLRF2 PF05812.7 EEQ76839.1 - 1.3 8.8 5.2 2.2 8.1 3.2 1.7 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein 60KD_IMP PF02096.15 EEQ76839.1 - 1.4 8.4 3.9 2.1 7.9 2.7 1.1 1 0 0 1 1 1 0 60Kd inner membrane protein DUF1843 PF08898.5 EEQ76839.1 - 4.8 7.3 6.3 10 6.2 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) Mto2_bdg PF12808.2 EEQ76839.1 - 6.3 6.9 6.6 27 4.9 0.5 2.4 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region FlxA PF14282.1 EEQ76839.1 - 7.4 6.5 14.7 42 4.1 10.2 2.0 1 1 0 1 1 1 0 FlxA-like protein 7kD_coat PF02495.12 EEQ76844.1 - 0.27 10.7 2.4 0.34 10.3 0.6 1.9 2 0 0 2 2 2 0 7kD viral coat protein DUF1805 PF08827.6 EEQ76845.1 - 0.17 11.7 0.1 0.38 10.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Pkinase PF00069.20 EEQ76846.1 - 7.3e-07 28.5 0.0 1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EEQ76846.1 - 0.0063 15.5 0.7 0.011 14.7 0.5 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family IL11 PF07400.6 EEQ76846.1 - 0.0078 15.7 0.7 0.19 11.2 0.0 2.1 2 0 0 2 2 2 1 Interleukin 11 PTSIIA_gutA PF03829.8 EEQ76846.1 - 0.045 13.4 0.0 0.089 12.4 0.0 1.5 1 0 0 1 1 1 0 PTS system glucitol/sorbitol-specific IIA component DUF3220 PF11516.3 EEQ76848.1 - 0.093 12.7 0.2 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) DUF3723 PF12520.3 EEQ76849.1 - 1.6e-33 115.9 0.0 4.8e-20 71.5 0.0 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF3723) CBFD_NFYB_HMF PF00808.18 EEQ76851.1 - 0.094 12.7 0.3 0.14 12.1 0.2 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FAD_binding_8 PF08022.7 EEQ76852.1 - 4.2e-05 23.3 0.0 9.5e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain zf-C3HC4 PF00097.20 EEQ76854.1 - 2.7e-05 23.7 5.0 9.8e-05 21.9 3.6 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ76854.1 - 0.00034 20.1 10.0 0.00055 19.5 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ76854.1 - 0.00066 19.6 6.1 0.0018 18.2 4.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ76854.1 - 0.0052 16.4 9.7 0.011 15.3 6.7 1.6 1 1 0 1 1 1 1 zinc-RING finger domain TMF_TATA_bd PF12325.3 EEQ76854.1 - 0.017 14.8 2.4 0.023 14.3 1.6 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding zf-RING_2 PF13639.1 EEQ76854.1 - 0.048 13.4 12.3 0.095 12.5 8.6 1.5 1 0 0 1 1 1 0 Ring finger domain FlxA PF14282.1 EEQ76854.1 - 0.054 13.4 1.8 0.093 12.6 1.2 1.3 1 0 0 1 1 1 0 FlxA-like protein Seryl_tRNA_N PF02403.17 EEQ76854.1 - 0.085 12.8 2.2 0.15 12.1 1.5 1.3 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ARD PF03079.9 EEQ76854.1 - 0.1 12.5 1.7 0.15 11.9 1.2 1.2 1 0 0 1 1 1 0 ARD/ARD' family Macoilin PF09726.4 EEQ76854.1 - 0.11 10.7 3.8 0.13 10.4 2.7 1.1 1 0 0 1 1 1 0 Transmembrane protein CRA PF06589.6 EEQ76854.1 - 0.13 11.5 0.5 0.19 11.0 0.3 1.4 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) zf-C3HC4_4 PF15227.1 EEQ76854.1 - 0.35 10.7 9.5 0.43 10.4 5.6 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EEQ76854.1 - 0.62 9.8 6.4 1.1 9.1 4.4 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF3435 PF11917.3 EEQ76855.1 - 1.4e-68 231.6 0.2 1.7e-68 231.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Peptidase_S8 PF00082.17 EEQ76856.1 - 2.8e-52 177.6 5.3 3.7e-52 177.2 3.7 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EEQ76856.1 - 7.8e-15 55.2 0.0 1.5e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Chitin_synth_2 PF03142.10 EEQ76857.1 - 3.5e-230 764.8 0.0 5.8e-230 764.1 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EEQ76857.1 - 9.3e-74 248.7 0.0 5.8e-73 246.0 0.0 2.1 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EEQ76857.1 - 1.3e-17 63.2 0.0 3.2e-10 39.6 0.0 2.8 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 EEQ76857.1 - 2.5e-17 63.2 1.8 2.5e-17 63.2 1.2 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 EEQ76857.1 - 2e-16 59.5 2.1 1.2e-15 57.0 1.3 2.2 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 EEQ76857.1 - 3.7e-15 56.3 0.0 7.5e-13 48.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EEQ76857.1 - 4.5e-06 26.0 0.0 1.4e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EEQ76857.1 - 0.0079 15.8 0.0 0.13 11.9 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Chitin_synth_2 PF03142.10 EEQ76859.1 - 1.6e-256 851.8 0.6 2.7e-256 851.0 0.4 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EEQ76859.1 - 6.2e-177 589.7 0.0 8e-177 589.3 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EEQ76859.1 - 6.9e-20 70.6 0.0 1e-15 57.2 0.0 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EEQ76859.1 - 9.6e-17 60.5 1.9 2.8e-16 59.0 0.9 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 EEQ76859.1 - 2e-14 53.7 3.2 2e-14 53.7 2.2 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EEQ76859.1 - 5.5e-14 52.5 0.1 1.2e-10 41.5 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EEQ76859.1 - 0.00026 20.7 0.0 0.021 14.5 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EEQ76859.1 - 0.0024 17.1 0.2 0.055 12.7 0.1 2.8 2 1 0 2 2 2 1 Glycosyl transferase family 21 VirD1 PF07328.6 EEQ76859.1 - 0.041 13.7 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 AAA_16 PF13191.1 EEQ76859.1 - 0.06 13.3 0.1 0.2 11.5 0.1 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EEQ76859.1 - 0.06 13.4 0.0 0.2 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EEQ76859.1 - 0.28 10.0 0.2 0.55 9.0 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein OTT_1508_deam PF14441.1 EEQ76860.1 - 7.2e-32 110.1 0.1 1.1e-31 109.6 0.1 1.3 1 0 0 1 1 1 1 OTT_1508-like deaminase KH_1 PF00013.24 EEQ76861.1 - 3.8e-27 93.6 1.8 1e-07 31.4 0.2 6.9 8 0 0 8 8 8 5 KH domain KH_3 PF13014.1 EEQ76861.1 - 6.8e-22 76.6 8.1 0.00029 20.4 0.2 7.2 7 0 0 7 7 7 5 KH domain RD3 PF14473.1 EEQ76862.1 - 0.047 13.1 0.6 0.081 12.4 0.4 1.3 1 0 0 1 1 1 0 RD3 protein Malate_DH PF12434.3 EEQ76862.1 - 0.97 9.1 4.1 2.5 7.8 2.8 1.8 1 1 0 1 1 1 0 Malate dehydrogenase enzyme Methyltransf_23 PF13489.1 EEQ76863.1 - 1.4e-13 50.9 0.0 2e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ76863.1 - 0.00042 20.8 0.1 0.067 13.7 0.0 2.7 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ76863.1 - 0.0017 17.9 0.0 0.012 15.2 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ76863.1 - 0.0018 18.6 0.0 0.012 16.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ76863.1 - 0.03 14.7 0.0 0.088 13.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain HAD_2 PF13419.1 EEQ76865.1 - 2.5e-30 106.0 0.2 3.3e-30 105.6 0.2 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ76865.1 - 0.00054 19.6 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hemerythrin PF01814.18 EEQ76866.1 - 5.2e-05 23.4 0.1 7.6e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Dynactin PF12455.3 EEQ76868.1 - 1.4e-100 335.7 2.9 1.4e-100 335.7 2.0 3.1 4 1 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 EEQ76868.1 - 1.7e-21 75.6 0.2 3e-21 74.8 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain HALZ PF02183.13 EEQ76868.1 - 0.007 16.0 1.1 0.007 16.0 0.8 8.7 7 1 2 9 9 9 2 Homeobox associated leucine zipper DUF2353 PF09789.4 EEQ76868.1 - 0.94 8.6 61.5 0.03 13.6 16.4 3.7 2 1 1 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) zf-rbx1 PF12678.2 EEQ76869.1 - 0.023 14.8 1.0 0.047 13.8 0.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger Solute_trans_a PF03619.11 EEQ76871.1 - 6.8e-98 327.3 3.6 9e-98 326.9 2.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha GTP_EFTU PF00009.22 EEQ76873.1 - 1.8e-62 210.1 0.1 2.4e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EEQ76873.1 - 5.4e-38 129.2 0.0 1.3e-37 127.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EEQ76873.1 - 6.1e-21 74.0 0.0 1.5e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EEQ76873.1 - 6.1e-12 45.2 0.0 1.6e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EEQ76873.1 - 1.2e-10 41.3 0.0 6.4e-10 39.0 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEQ76873.1 - 1.6e-05 24.7 0.0 4.1e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RRM_6 PF14259.1 EEQ76874.1 - 1.5e-10 40.8 0.0 7.4e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ76874.1 - 2.9e-10 39.8 0.0 5.3e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EEQ76874.1 - 5.2e-08 32.8 0.0 1.3e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 EEQ76874.1 - 0.00011 21.7 0.0 0.0025 17.4 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEQ76874.1 - 0.016 15.0 0.0 0.095 12.4 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Dicty_REP PF05086.7 EEQ76874.1 - 9.4 3.8 5.3 16 3.1 3.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein adh_short PF00106.20 EEQ76875.1 - 5.1e-25 88.3 0.5 1.1e-24 87.2 0.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ76875.1 - 7.7e-22 78.2 0.0 1e-21 77.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ76875.1 - 0.00025 20.7 0.8 0.00085 19.0 0.6 1.8 1 1 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.16 EEQ76875.1 - 0.33 10.7 1.7 0.32 10.8 0.3 1.8 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF663 PF04950.7 EEQ76878.1 - 2.5e-92 309.0 0.0 6.4e-92 307.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EEQ76878.1 - 1.6e-26 91.6 0.0 4.1e-26 90.3 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EEQ76878.1 - 2.1e-07 30.5 0.0 8.5e-05 22.0 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EEQ76878.1 - 7.9e-06 25.9 0.0 3.4e-05 23.9 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEQ76878.1 - 1.4e-05 25.2 0.0 3.7e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EEQ76878.1 - 0.00021 21.4 0.0 0.00054 20.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEQ76878.1 - 0.0003 21.5 0.0 0.0003 21.5 0.0 4.8 3 1 2 5 5 2 1 AAA domain MobB PF03205.9 EEQ76878.1 - 0.00039 20.1 0.1 0.0009 18.9 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EEQ76878.1 - 0.0013 18.6 0.0 0.0056 16.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EEQ76878.1 - 0.0018 18.7 0.3 0.0068 16.8 0.0 2.1 2 0 0 2 2 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEQ76878.1 - 0.0031 17.4 0.1 0.0094 15.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EEQ76878.1 - 0.0032 16.9 0.0 0.036 13.5 0.0 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EEQ76878.1 - 0.0035 17.0 0.0 0.0079 15.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.22 EEQ76878.1 - 0.0037 17.5 1.0 0.0094 16.2 0.0 2.2 2 0 0 2 2 1 1 ABC transporter AAA_24 PF13479.1 EEQ76878.1 - 0.0039 16.8 0.1 0.011 15.2 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ76878.1 - 0.0051 16.5 0.1 0.014 15.1 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain NB-ARC PF00931.17 EEQ76878.1 - 0.007 15.2 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NTPase_1 PF03266.10 EEQ76878.1 - 0.008 15.9 0.2 0.017 14.8 0.1 1.5 1 0 0 1 1 1 1 NTPase AAA_14 PF13173.1 EEQ76878.1 - 0.0087 15.9 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EEQ76878.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 EEQ76878.1 - 0.015 14.7 0.0 0.044 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EEQ76878.1 - 0.015 14.9 0.2 0.049 13.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) cobW PF02492.14 EEQ76878.1 - 0.023 14.1 0.1 0.057 12.8 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EEQ76878.1 - 0.04 13.1 0.0 0.076 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EEQ76878.1 - 0.069 12.6 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Adeno_IVa2 PF02456.10 EEQ76878.1 - 0.38 9.3 0.0 0.61 8.6 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_11 PF13086.1 EEQ76878.1 - 1.1 8.8 5.4 1.5 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Inhibitor_I9 PF05922.11 EEQ76881.1 - 4.5e-05 23.9 0.1 5.5e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 Radical_SAM PF04055.16 EEQ76881.1 - 0.08 13.1 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 Radical SAM superfamily DUF3425 PF11905.3 EEQ76883.1 - 1e-27 96.7 0.5 1.8e-27 95.8 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EEQ76883.1 - 9.7e-05 22.2 3.4 0.00019 21.2 2.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor DUF3446 PF11928.3 EEQ76883.1 - 0.033 14.3 22.4 0.099 12.8 3.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) bZIP_2 PF07716.10 EEQ76883.1 - 0.7 9.7 9.8 0.085 12.6 3.6 1.8 2 0 0 2 2 2 0 Basic region leucine zipper BCDHK_Adom3 PF10436.4 EEQ76886.1 - 7e-43 145.9 0.0 9.4e-43 145.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EEQ76886.1 - 9.4e-15 54.3 0.0 3.2e-14 52.5 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EEQ76886.1 - 0.037 13.8 0.0 0.11 12.2 0.0 1.9 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain Carboxyl_trans PF01039.17 EEQ76887.1 - 6.6e-79 265.5 0.0 8.5e-79 265.1 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EEQ76888.1 - 2.2e-53 180.7 0.0 3.2e-53 180.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EEQ76888.1 - 1.2e-30 105.6 0.0 4.3e-30 103.8 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EEQ76888.1 - 1.1e-29 102.7 0.0 2e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EEQ76888.1 - 4.4e-19 68.9 0.0 8.5e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EEQ76888.1 - 4e-12 45.6 2.3 1.9e-11 43.4 0.2 2.8 3 0 0 3 3 3 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EEQ76888.1 - 6e-11 41.6 0.0 2.2e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EEQ76888.1 - 6.1e-10 38.8 0.0 1.3e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EEQ76888.1 - 3.8e-07 29.6 0.0 7e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EEQ76888.1 - 2.7e-05 24.1 0.0 6.6e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 EEQ76888.1 - 0.0042 16.2 0.0 0.0093 15.1 0.0 1.5 1 0 0 1 1 1 1 HlyD family secretion protein RnfC_N PF13375.1 EEQ76888.1 - 0.0054 16.4 0.0 0.015 14.9 0.0 1.8 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.1 EEQ76888.1 - 0.0061 16.2 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like RimK PF08443.6 EEQ76888.1 - 0.033 13.6 0.0 0.086 12.3 0.0 1.7 2 0 0 2 2 2 0 RimK-like ATP-grasp domain AnfO_nitrog PF09582.5 EEQ76888.1 - 0.034 13.2 0.0 0.071 12.2 0.0 1.4 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) DUF2118 PF09891.4 EEQ76888.1 - 0.046 13.4 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) GCN5L1 PF06320.8 EEQ76889.1 - 1.9e-10 40.6 3.9 2.4e-10 40.2 2.7 1.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) DUF3552 PF12072.3 EEQ76889.1 - 0.0031 16.7 7.1 0.0031 16.7 5.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3552) DUF2884 PF11101.3 EEQ76889.1 - 0.008 15.5 2.2 0.013 14.9 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) SCP-1 PF05483.7 EEQ76889.1 - 0.012 13.4 4.4 0.014 13.2 3.0 1.1 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) AAA_13 PF13166.1 EEQ76889.1 - 0.023 13.1 2.9 0.026 12.9 2.0 1.0 1 0 0 1 1 1 0 AAA domain DUF848 PF05852.6 EEQ76889.1 - 0.027 14.3 7.2 0.031 14.1 4.2 1.6 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) HAUS6_N PF14661.1 EEQ76889.1 - 0.053 12.8 4.3 0.06 12.6 3.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF342 PF03961.8 EEQ76889.1 - 0.3 9.4 3.8 0.33 9.3 2.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3735 PF12537.3 EEQ76889.1 - 0.3 11.1 1.4 0.61 10.1 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3735) DivIC PF04977.10 EEQ76889.1 - 0.31 10.5 3.5 0.59 9.6 2.4 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF4337 PF14235.1 EEQ76889.1 - 0.4 10.4 3.1 0.64 9.8 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF1664 PF07889.7 EEQ76889.1 - 0.44 10.3 3.2 0.77 9.5 2.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.10 EEQ76889.1 - 0.48 9.5 5.1 0.51 9.4 3.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG6 PF04111.7 EEQ76889.1 - 0.7 8.8 7.4 0.85 8.5 5.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TBCA PF02970.11 EEQ76889.1 - 1.4 9.0 8.1 2.2 8.4 5.1 1.9 1 1 1 2 2 2 0 Tubulin binding cofactor A Adeno_PIX PF03955.9 EEQ76889.1 - 2.5 8.6 4.9 2.6 8.5 2.9 1.4 1 1 0 1 1 1 0 Adenovirus hexon-associated protein (IX) DUF2098 PF09871.4 EEQ76889.1 - 4.8 7.1 8.1 4.8 7.1 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) DNA_mis_repair PF01119.14 EEQ76890.1 - 8.5e-20 70.3 0.0 5e-18 64.6 0.0 2.5 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 EEQ76890.1 - 2.5e-18 66.0 0.1 1.4e-17 63.6 0.1 2.3 1 1 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 EEQ76890.1 - 1.8e-13 50.3 0.2 9.2e-13 48.0 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EEQ76890.1 - 5.9e-12 45.2 0.0 1.6e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Serinc PF03348.10 EEQ76891.1 - 1.4e-173 577.6 8.8 1.6e-173 577.3 6.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) MFS_1 PF07690.11 EEQ76892.1 - 7.7e-19 67.6 18.0 2.1e-18 66.1 12.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.8 EEQ76892.1 - 1.5e-08 34.1 0.9 3.6e-08 32.9 0.6 1.6 1 0 0 1 1 1 1 Nodulin-like GATA PF00320.22 EEQ76894.1 - 2.7e-16 58.6 3.0 5.2e-16 57.6 2.1 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 EEQ76894.1 - 0.0051 16.0 0.5 0.0094 15.2 0.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding CENP-F_leu_zip PF10473.4 EEQ76894.1 - 0.017 15.0 6.6 0.51 10.1 1.4 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_A_type_inc PF04508.7 EEQ76894.1 - 0.083 12.7 3.1 4.1 7.4 0.4 3.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF4618 PF15397.1 EEQ76894.1 - 0.098 11.9 2.5 0.14 11.5 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DZR PF12773.2 EEQ76894.1 - 0.1 12.4 0.8 0.24 11.2 0.5 1.6 1 1 0 1 1 1 0 Double zinc ribbon DUF4164 PF13747.1 EEQ76894.1 - 0.68 10.1 10.1 1.1 9.3 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) WD40_alt PF14077.1 EEQ76894.1 - 1.5 8.5 4.4 30 4.3 0.0 3.2 2 1 1 3 3 3 0 Alternative WD40 repeat motif PspB PF06667.7 EEQ76894.1 - 3.6 7.5 5.0 25 4.9 1.1 2.3 2 0 0 2 2 2 0 Phage shock protein B SKG6 PF08693.5 EEQ76896.1 - 0.00075 18.7 1.1 0.0022 17.2 0.7 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Sporozoite_P67 PF05642.6 EEQ76896.1 - 0.42 8.4 9.2 0.48 8.2 6.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_capsid PF06112.6 EEQ76896.1 - 6.7 6.7 8.2 13 5.8 5.7 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein PI3_PI4_kinase PF00454.22 EEQ76897.1 - 7.2e-39 133.6 0.0 1.2e-38 132.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SNF2_N PF00176.18 EEQ76898.1 - 2.1e-61 207.3 0.3 3.3e-61 206.6 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ76898.1 - 1.5e-08 34.3 0.2 1.4e-07 31.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEQ76898.1 - 1.3e-05 24.7 0.0 3.9e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase HIRAN PF08797.6 EEQ76898.1 - 0.024 14.5 0.0 0.1 12.5 0.0 2.2 2 0 0 2 2 2 0 HIRAN domain ATPase-cat_bd PF12156.3 EEQ76898.1 - 0.13 12.8 2.0 0.57 10.7 1.4 2.1 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase zf-RING_5 PF14634.1 EEQ76898.1 - 0.23 11.1 5.9 0.45 10.2 4.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Med21 PF11221.3 EEQ76899.1 - 5.7e-53 178.7 15.5 3.7e-52 176.1 10.7 1.8 1 1 0 1 1 1 1 Subunit 21 of Mediator complex ATG16 PF08614.6 EEQ76899.1 - 0.0019 18.0 3.2 0.0028 17.5 2.2 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) SPX PF03105.14 EEQ76899.1 - 0.0094 15.7 0.1 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 SPX domain Spore_III_AB PF09548.5 EEQ76899.1 - 0.029 14.1 0.8 0.037 13.7 0.1 1.4 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Dicty_REP PF05086.7 EEQ76899.1 - 0.035 11.8 0.1 0.04 11.6 0.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Med9 PF07544.8 EEQ76899.1 - 0.056 13.1 1.4 0.16 11.7 1.0 2.1 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 TMCO5 PF14992.1 EEQ76899.1 - 0.06 12.4 0.5 0.084 11.9 0.4 1.2 1 0 0 1 1 1 0 TMCO5 family TFIIA PF03153.8 EEQ76899.1 - 0.15 11.9 3.0 0.17 11.7 2.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.9 EEQ76899.1 - 0.45 10.2 2.2 0.55 9.9 1.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med3 PF11593.3 EEQ76899.1 - 2.2 7.4 11.5 2.8 7.0 8.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2034 PF10356.4 EEQ76900.1 - 2.4e-33 114.8 0.0 2.7e-18 65.7 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EEQ76900.1 - 1.2e-07 31.5 0.0 2.6e-07 30.4 0.0 1.5 2 0 0 2 2 2 1 Restriction endonuclease DUF3431 PF11913.3 EEQ76902.1 - 9.9e-89 296.6 0.2 1.2e-88 296.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Methyltransf_31 PF13847.1 EEQ76904.1 - 2.6e-10 40.1 0.0 4.4e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ76904.1 - 1.3e-09 38.6 0.0 2.9e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ76904.1 - 1.2e-08 35.3 0.0 2.9e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ76904.1 - 1.2e-06 28.9 0.0 2.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ76904.1 - 1.5e-06 28.5 0.0 3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ76904.1 - 0.00012 21.8 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ76904.1 - 0.00012 22.1 0.1 0.00026 21.0 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEQ76904.1 - 0.00022 20.6 0.0 0.00038 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EEQ76904.1 - 0.00038 19.6 0.0 0.0032 16.6 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EEQ76904.1 - 0.00042 19.4 0.0 0.0054 15.7 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.14 EEQ76904.1 - 0.00091 18.8 0.0 0.0033 16.9 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 EEQ76904.1 - 0.03 15.1 0.0 0.095 13.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain APH PF01636.18 EEQ76905.1 - 5.5e-10 39.3 0.0 1.1e-08 35.1 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ76905.1 - 6e-06 25.9 0.0 8.9e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase zf-RING_2 PF13639.1 EEQ76906.1 - 2e-14 53.1 17.4 2e-13 49.9 6.0 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 EEQ76906.1 - 8.8e-10 38.1 10.0 1.8e-08 33.9 2.2 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EEQ76906.1 - 9e-09 35.1 9.8 6.5e-08 32.4 1.6 2.6 2 0 0 2 2 2 2 zinc-finger zf-rbx1 PF12678.2 EEQ76906.1 - 1.2e-08 34.9 8.1 1.6e-08 34.5 2.2 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EEQ76906.1 - 2.4e-08 33.8 14.7 4e-07 29.9 4.9 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ76906.1 - 3.8e-06 26.4 13.2 1.4e-05 24.6 4.3 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ76906.1 - 6.8e-06 25.7 11.7 7.5e-06 25.5 3.0 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EEQ76906.1 - 0.00013 21.7 5.7 0.0005 19.8 1.4 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.14 EEQ76906.1 - 0.0032 17.1 3.3 0.023 14.3 0.1 2.2 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EEQ76906.1 - 0.0058 16.4 4.1 0.81 9.5 0.1 3.0 3 0 0 3 3 3 2 Double zinc ribbon PHD PF00628.24 EEQ76906.1 - 0.018 14.6 5.4 0.018 14.6 3.7 2.3 2 0 0 2 2 2 0 PHD-finger Prok-RING_4 PF14447.1 EEQ76906.1 - 0.94 9.0 9.0 0.69 9.5 3.2 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.3 EEQ76906.1 - 1.4 8.9 9.2 0.59 10.1 3.4 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EEQ76906.1 - 2.3 7.8 12.9 0.059 12.9 2.7 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EEQ76906.1 - 3.1 7.7 13.8 2 8.3 1.1 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Fis1_TPR_C PF14853.1 EEQ76908.1 - 1.8e-26 91.7 0.8 3e-26 91.0 0.5 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EEQ76908.1 - 1.3e-17 62.7 0.1 2.4e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EEQ76908.1 - 0.0022 17.7 1.3 0.0054 16.5 0.9 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ76908.1 - 0.0033 18.0 0.2 0.0069 17.0 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Spc24 PF08286.6 EEQ76909.1 - 8.8e-40 135.0 1.0 2.8e-39 133.4 0.1 1.9 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 APG6 PF04111.7 EEQ76909.1 - 0.19 10.7 3.0 0.23 10.4 2.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3166 PF11365.3 EEQ76909.1 - 0.2 12.0 2.6 0.44 11.0 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) WXG100 PF06013.7 EEQ76909.1 - 0.28 11.2 1.9 0.5 10.4 0.0 2.2 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Viral_P18 PF04521.8 EEQ76909.1 - 2.3 7.6 4.6 5.7 6.4 0.3 2.2 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DSBA PF01323.15 EEQ76911.1 - 6.9e-30 104.0 0.0 8.1e-30 103.8 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.1 EEQ76911.1 - 0.025 14.3 0.1 0.055 13.2 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin domain Aminotran_5 PF00266.14 EEQ76912.1 - 2.6e-22 79.0 0.0 3.8e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EEQ76912.1 - 3.1e-05 23.1 0.0 4.2e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EEQ76912.1 - 0.009 15.0 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GYF PF02213.11 EEQ76913.1 - 1.1e-15 56.9 0.1 2.7e-15 55.6 0.1 1.7 1 0 0 1 1 1 1 GYF domain MAPEG PF01124.13 EEQ76916.1 - 1.1e-19 70.3 0.9 1.3e-19 70.0 0.6 1.0 1 0 0 1 1 1 1 MAPEG family DUF981 PF06168.6 EEQ76916.1 - 0.042 13.6 0.1 0.061 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF981) ADH_zinc_N PF00107.21 EEQ76917.1 - 2.3e-23 82.1 0.1 3.4e-23 81.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEQ76917.1 - 1.1e-09 39.2 0.0 3.5e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEQ76917.1 - 9e-05 22.1 0.0 0.00019 21.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EEQ76917.1 - 0.016 15.2 0.0 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 EEQ76917.1 - 0.029 14.2 1.3 2.7 7.8 0.6 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Trp_syntA PF00290.15 EEQ76919.1 - 5.9e-88 293.7 0.0 8.8e-88 293.1 0.0 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EEQ76919.1 - 4.2e-43 147.7 0.9 1.2e-42 146.2 0.6 1.7 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GFO_IDH_MocA PF01408.17 EEQ76920.1 - 2e-15 57.3 0.1 3.6e-15 56.5 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EEQ76920.1 - 3.9e-08 33.0 0.0 7.1e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Pkinase PF00069.20 EEQ76921.1 - 2.4e-09 36.7 0.3 5.6e-09 35.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 EEQ76921.1 - 0.0081 15.9 0.0 0.028 14.1 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EEQ76921.1 - 0.023 13.7 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase IncA PF04156.9 EEQ76922.1 - 1.5 8.3 4.5 1.7 8.1 3.2 1.1 1 0 0 1 1 1 0 IncA protein ATP-synt_ab PF00006.20 EEQ76924.1 - 1.1e-61 208.1 0.0 1.4e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EEQ76924.1 - 8e-17 61.7 0.0 1.4e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EEQ76924.1 - 4.7e-11 42.7 0.2 9.6e-11 41.7 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EEQ76924.1 - 0.0019 18.0 0.1 0.0041 16.9 0.1 1.5 1 0 0 1 1 1 1 HAS barrel domain Peptidase_S10 PF00450.17 EEQ76925.1 - 1.5e-77 261.4 0.0 3.4e-77 260.3 0.0 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase Beta-lactamase PF00144.19 EEQ76926.1 - 5.9e-30 104.4 0.1 7.9e-30 103.9 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Usp PF00582.21 EEQ76927.1 - 1.4e-20 73.9 0.6 9.1e-13 48.5 0.1 2.7 2 0 0 2 2 2 2 Universal stress protein family DnaJ PF00226.26 EEQ76928.1 - 6e-24 83.5 2.9 1.9e-23 81.9 2.0 1.9 1 0 0 1 1 1 1 DnaJ domain V-SNARE PF05008.10 EEQ76928.1 - 0.03 14.4 0.5 0.64 10.2 0.1 2.9 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF4461 PF14688.1 EEQ76928.1 - 0.14 11.4 0.4 0.24 10.6 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4461) dCMP_cyt_deam_1 PF00383.17 EEQ76929.1 - 2e-11 43.4 0.0 3.8e-10 39.3 0.0 2.6 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Herpes_U47 PF05467.6 EEQ76929.1 - 0.0012 16.7 1.3 0.0017 16.3 0.9 1.2 1 0 0 1 1 1 1 Herpesvirus glycoprotein U47 APOBEC_N PF08210.6 EEQ76929.1 - 0.084 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Stn1 PF10451.4 EEQ76931.1 - 3.4e-13 49.0 0.0 1.1e-07 30.9 0.0 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 Stc1 PF12898.2 EEQ76934.1 - 1.8e-23 82.4 6.1 3.3e-23 81.5 4.3 1.4 1 0 0 1 1 1 1 Stc1 domain zf-BED PF02892.10 EEQ76934.1 - 3.7 7.3 5.9 18 5.1 0.4 2.7 2 0 0 2 2 2 0 BED zinc finger SIMPL PF04402.9 EEQ76935.1 - 4.1e-30 105.2 1.3 4.6e-30 105.0 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Pkinase PF00069.20 EEQ76938.1 - 1.3e-62 211.3 0.0 1.8e-62 210.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ76938.1 - 2.6e-34 118.4 0.0 5.6e-34 117.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EEQ76938.1 - 0.021 13.6 0.0 0.041 12.6 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1387 PF07139.6 EEQ76938.1 - 0.62 9.6 0.0 0.62 9.6 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1387) RNase_PH PF01138.16 EEQ76939.1 - 8.2e-13 48.8 0.0 1.6e-11 44.6 0.0 2.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 ATP-synt_A PF00119.15 EEQ76940.1 - 0.055 12.9 0.8 0.078 12.4 0.6 1.1 1 0 0 1 1 1 0 ATP synthase A chain PBP_sp32 PF07222.7 EEQ76940.1 - 0.11 11.6 0.2 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Cytochrom_C PF00034.16 EEQ76941.1 - 1.8e-10 41.4 0.0 2.8e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EEQ76941.1 - 8.5e-08 32.2 3.4 4.7e-07 29.8 2.4 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EEQ76941.1 - 0.0025 17.2 0.4 0.011 15.2 0.0 2.0 2 1 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.9 EEQ76941.1 - 0.064 13.5 0.0 0.1 12.9 0.0 1.3 1 1 0 1 1 1 0 Di-haem cytochrome c peroxidase Toxin_12 PF07740.7 EEQ76943.1 - 5.3e-05 23.6 33.2 0.00012 22.4 5.7 3.5 3 0 0 3 3 3 2 Ion channel inhibitory toxin DUF1668 PF07893.8 EEQ76944.1 - 0.086 11.9 0.4 0.27 10.3 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1668) ATE_C PF04377.10 EEQ76946.1 - 5.2e-43 146.1 4.8 8.9e-43 145.4 3.4 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EEQ76946.1 - 1.4e-12 47.2 1.6 3.9e-07 29.7 0.2 2.5 2 0 0 2 2 2 2 Arginine-tRNA-protein transferase, N terminus Cu_amine_oxidN3 PF02728.11 EEQ76948.1 - 0.031 14.3 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Copper amine oxidase, N3 domain NUDIX PF00293.23 EEQ76949.1 - 6.7e-18 64.6 0.4 7.9e-18 64.4 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain TraI_2 PF07514.6 EEQ76949.1 - 0.018 13.7 1.5 0.035 12.8 1.0 1.4 1 1 0 1 1 1 0 Putative helicase RNA_pol_A_bac PF01000.21 EEQ76950.1 - 3.4e-32 110.9 0.0 5.7e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EEQ76950.1 - 2.4e-13 49.0 0.0 4.2e-13 48.1 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain tRNA-synt_1b PF00579.20 EEQ76951.1 - 3e-59 200.5 0.0 3.8e-59 200.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Fer4_5 PF12801.2 EEQ76951.1 - 0.056 13.2 0.9 0.11 12.3 0.6 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain Glyco_hydro_16 PF00722.16 EEQ76954.1 - 6.7e-42 142.8 0.5 1.1e-41 142.1 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF566 PF04484.7 EEQ76954.1 - 3.1 7.2 8.1 4.4 6.7 5.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Annexin PF00191.15 EEQ76955.1 - 3.8e-34 116.3 2.3 6.6e-11 41.9 0.0 4.8 4 1 0 4 4 4 4 Annexin p450 PF00067.17 EEQ76957.1 - 1.9e-57 194.7 0.0 2.4e-42 145.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Glyco_hydro_20 PF00728.17 EEQ76958.1 - 2.2e-80 270.4 0.0 2.9e-80 270.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EEQ76958.1 - 1.3e-24 87.2 0.0 2.8e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EEQ76958.1 - 0.00036 21.0 0.1 0.0065 17.0 0.0 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 zf-CCCH_2 PF14608.1 EEQ76959.1 - 1.7e-08 34.1 53.9 5.7e-06 26.1 7.5 5.6 5 1 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 EEQ76959.1 - 0.0074 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Amino_oxidase PF01593.19 EEQ76960.1 - 1.7e-20 73.5 0.1 8.5e-15 54.7 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EEQ76960.1 - 8.5e-13 48.1 0.0 3.4e-12 46.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEQ76960.1 - 7.3e-08 31.6 0.2 4.5e-07 29.0 0.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EEQ76960.1 - 2e-05 24.4 0.0 0.0022 17.7 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EEQ76960.1 - 0.00012 20.6 0.0 0.002 16.7 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EEQ76960.1 - 0.0002 21.6 0.0 0.03 14.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEQ76960.1 - 0.0028 16.8 0.0 0.0049 15.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EEQ76960.1 - 0.0028 17.5 0.0 0.0061 16.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEQ76960.1 - 0.0038 17.3 0.0 0.062 13.3 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEQ76960.1 - 0.0038 16.1 0.0 0.0064 15.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.14 EEQ76960.1 - 0.032 12.4 0.0 0.047 11.8 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.14 EEQ76960.1 - 0.041 12.9 0.5 0.94 8.4 0.1 2.8 2 1 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.2 EEQ76960.1 - 0.058 12.4 0.1 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EEQ76960.1 - 0.083 11.7 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 EEQ76960.1 - 0.12 12.5 0.0 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding Mago-bind PF09282.5 EEQ76961.1 - 1e-13 50.5 3.7 1.9e-13 49.6 2.6 1.5 1 0 0 1 1 1 1 Mago binding DASH_Spc34 PF08657.5 EEQ76961.1 - 0.12 12.0 8.2 0.17 11.5 5.7 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 zf-UBR PF02207.15 EEQ76962.1 - 7.9e-18 63.9 15.3 2.3e-17 62.4 10.6 1.9 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EEQ76962.1 - 7e-06 25.6 0.1 2.5e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.1 EEQ76962.1 - 0.0002 21.0 1.8 0.0002 21.0 1.3 4.2 3 0 0 3 3 3 1 Ring finger domain DUF4419 PF14388.1 EEQ76962.1 - 0.09 11.9 0.4 0.25 10.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4419) Mito_fiss_reg PF05308.6 EEQ76962.1 - 0.34 10.2 1.5 0.74 9.1 1.0 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator RED_N PF07808.8 EEQ76963.1 - 2.3e-09 36.8 0.4 5.4e-09 35.6 0.3 1.6 1 0 0 1 1 1 1 RED-like protein N-terminal region Glyco_hydro_cc PF11790.3 EEQ76964.1 - 4.7e-59 199.7 0.0 5.8e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core WD40 PF00400.27 EEQ76965.1 - 1.2e-65 215.1 18.5 6.3e-13 48.0 0.0 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EEQ76965.1 - 1.8e-09 37.6 0.0 0.0024 17.5 0.0 3.3 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EEQ76965.1 - 1.5e-06 26.6 1.1 0.051 11.7 0.0 4.1 2 1 2 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.7 EEQ76965.1 - 0.00088 18.8 0.2 33 4.2 0.0 4.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF1513 PF07433.6 EEQ76965.1 - 0.0014 17.5 0.3 2.1 7.1 0.0 3.2 1 1 2 4 4 4 3 Protein of unknown function (DUF1513) DUF3312 PF11768.3 EEQ76965.1 - 0.0029 15.9 0.0 0.0095 14.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) Nbas_N PF15492.1 EEQ76965.1 - 0.011 14.9 0.6 6.9 5.6 0.0 3.5 2 2 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Hira PF07569.6 EEQ76965.1 - 0.027 13.6 0.1 20 4.2 0.0 3.9 3 1 2 5 5 5 0 TUP1-like enhancer of split IKI3 PF04762.7 EEQ76965.1 - 0.079 10.7 0.0 0.29 8.8 0.0 1.8 2 0 0 2 2 2 0 IKI3 family Apc4_WD40 PF12894.2 EEQ76965.1 - 0.12 11.9 0.0 1.5 8.3 0.0 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Exo_endo_phos PF03372.18 EEQ76966.1 - 2e-16 60.7 0.0 3.2e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Thi4 PF01946.12 EEQ76967.1 - 1.5e-100 335.0 0.0 1.8e-100 334.7 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EEQ76967.1 - 1.5e-07 30.6 0.0 2.2e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EEQ76967.1 - 2.5e-05 23.3 0.2 8.5e-05 21.6 0.2 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EEQ76967.1 - 9.1e-05 22.4 0.5 0.00026 20.9 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EEQ76967.1 - 0.0009 19.0 0.7 0.0023 17.7 0.0 2.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EEQ76967.1 - 0.0054 16.8 0.1 0.0072 16.4 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEQ76967.1 - 0.0061 16.4 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEQ76967.1 - 0.022 13.6 0.4 0.067 12.0 0.2 1.8 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 EEQ76967.1 - 0.061 12.3 0.1 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 EEQ76967.1 - 0.097 11.2 0.2 0.14 10.7 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 EEQ76967.1 - 0.2 10.0 0.5 0.31 9.4 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Ppx-GppA PF02541.11 EEQ76970.1 - 6.9e-44 150.1 0.0 1.1e-43 149.5 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family SWI-SNF_Ssr4 PF08549.5 EEQ76971.1 - 1.7e-214 714.0 23.2 5.4e-214 712.3 16.1 1.7 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Chorion_2 PF03964.10 EEQ76971.1 - 4.5 7.8 12.5 0.094 13.2 2.5 2.4 2 0 0 2 2 2 0 Chorion family 2 Pil1 PF13805.1 EEQ76973.1 - 8.9e-94 313.6 2.1 1.1e-93 313.2 1.4 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 DNAPolymera_Pol PF11590.3 EEQ76973.1 - 0.085 12.5 0.7 0.51 10.0 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase catalytic subunit Pol DUF2508 PF10704.4 EEQ76973.1 - 0.11 12.7 3.2 2 8.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) DUF2765 PF10963.3 EEQ76973.1 - 0.12 12.3 0.2 0.28 11.1 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2765) Proteasome PF00227.21 EEQ76974.1 - 7.6e-49 165.5 0.2 9.2e-49 165.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF554 PF04474.7 EEQ76974.1 - 0.092 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF554) RNA_pol_Rpb2_6 PF00562.23 EEQ76975.1 - 8.9e-115 383.4 0.0 1.2e-114 383.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EEQ76975.1 - 6.8e-33 113.3 0.0 1e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpa2_4 PF06883.7 EEQ76975.1 - 1.2e-25 89.1 0.0 3.1e-25 87.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_3 PF04565.11 EEQ76975.1 - 3.6e-24 84.2 0.0 8e-24 83.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 EEQ76975.1 - 7.6e-24 84.1 0.0 1.4e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EEQ76975.1 - 2.7e-14 53.1 0.0 1.1e-13 51.1 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EEQ76975.1 - 0.00024 21.0 0.0 0.00058 19.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Arf PF00025.16 EEQ76977.1 - 5.1e-43 146.3 0.0 6.3e-43 146.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EEQ76977.1 - 2.3e-19 69.3 0.0 2.6e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ76977.1 - 1.2e-10 41.9 0.0 1.7e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EEQ76977.1 - 1.2e-07 31.0 0.0 1.4e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EEQ76977.1 - 2.1e-07 30.3 0.0 2.7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEQ76977.1 - 7.2e-07 29.1 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEQ76977.1 - 2.5e-05 23.7 0.0 0.00025 20.5 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 EEQ76977.1 - 0.00022 20.0 0.0 0.00061 18.5 0.0 1.7 1 1 0 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.18 EEQ76977.1 - 0.0011 18.8 0.0 0.013 15.3 0.1 2.0 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 EEQ76977.1 - 0.029 13.6 0.2 0.17 11.1 0.0 2.0 2 1 0 2 2 2 0 Ferrous iron transport protein B RCR PF12273.3 EEQ76978.1 - 4.3e-26 92.0 15.3 5.1e-26 91.7 10.6 1.0 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red TMEM51 PF15345.1 EEQ76978.1 - 0.0014 18.3 0.2 0.0034 17.1 0.1 1.5 1 1 0 1 1 1 1 Transmembrane protein 51 Shisa PF13908.1 EEQ76978.1 - 0.005 17.0 2.1 0.0084 16.3 1.5 1.5 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF1183 PF06682.7 EEQ76978.1 - 0.01 15.4 1.3 0.017 14.7 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) SLAC1 PF03595.12 EEQ76978.1 - 0.026 13.1 0.2 0.032 12.8 0.1 1.1 1 0 0 1 1 1 0 Voltage-dependent anion channel DUF3328 PF11807.3 EEQ76978.1 - 0.027 14.1 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Rhabdo_glycop PF00974.13 EEQ76978.1 - 0.054 11.7 0.3 0.071 11.3 0.2 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Ion_trans_2 PF07885.11 EEQ76978.1 - 0.06 13.0 0.1 0.079 12.6 0.1 1.2 1 0 0 1 1 1 0 Ion channel GP41 PF00517.12 EEQ76978.1 - 0.064 12.8 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 Retroviral envelope protein Cytochrom_B_N PF00033.14 EEQ76978.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB LSR PF05624.9 EEQ76979.1 - 0.0038 16.9 3.2 0.0064 16.1 2.2 1.4 1 0 0 1 1 1 1 Lipolysis stimulated receptor (LSR) Shisa PF13908.1 EEQ76979.1 - 0.0058 16.8 0.2 0.0062 16.7 0.1 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Lamp PF01299.12 EEQ76979.1 - 0.021 13.9 0.1 0.021 13.9 0.0 1.5 1 1 1 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) Corona_S2 PF01601.11 EEQ76979.1 - 1.2 7.1 4.6 1.4 6.9 3.2 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein CwfJ_C_1 PF04677.10 EEQ76983.1 - 2e-24 85.5 0.0 3.9e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EEQ76983.1 - 3.6e-22 78.6 0.2 6.7e-22 77.8 0.2 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Metallophos PF00149.23 EEQ76983.1 - 0.014 14.7 0.0 0.037 13.4 0.0 1.6 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase DUF1730 PF08331.5 EEQ76983.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) MIF PF01187.13 EEQ76984.1 - 2.3e-26 92.1 0.0 2.6e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.16 EEQ76984.1 - 0.061 12.9 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Tautomerase enzyme DRIM PF07539.7 EEQ76985.1 - 4.9e-48 162.1 0.0 2.4e-47 159.8 0.0 2.4 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT PF02985.17 EEQ76985.1 - 0.0033 17.3 6.5 20 5.5 0.0 8.4 10 0 0 10 10 10 1 HEAT repeat Ipi1_N PF12333.3 EEQ76985.1 - 0.0039 17.1 2.9 2.6 8.0 0.0 5.0 4 0 0 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation zf-DNL PF05180.7 EEQ76986.1 - 3.8e-29 100.1 0.8 6.6e-29 99.4 0.5 1.4 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.8 EEQ76986.1 - 0.014 15.0 0.2 0.026 14.1 0.1 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 EEQ76986.1 - 0.034 13.9 6.3 0.42 10.4 4.2 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-CSL PF05207.8 EEQ76986.1 - 0.069 12.6 0.3 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 CSL zinc finger TFIIS_C PF01096.13 EEQ76986.1 - 0.17 11.5 1.4 8.2 6.1 0.1 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Ribosomal_60s PF00428.14 EEQ76986.1 - 0.45 10.9 0.0 0.45 10.9 0.0 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ribosomal_L32p PF01783.18 EEQ76986.1 - 0.59 10.3 3.5 0.65 10.2 1.1 2.0 1 1 1 2 2 2 0 Ribosomal L32p protein family Cullin PF00888.17 EEQ76987.1 - 1.1e-133 446.8 9.2 1.1e-133 446.8 6.4 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 EEQ76987.1 - 7e-29 99.4 2.3 2.3e-28 97.7 0.4 2.7 2 0 0 2 2 2 1 Cullin protein neddylation domain Rrf2 PF02082.15 EEQ76987.1 - 0.012 15.6 0.1 0.036 14.1 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator HTH_20 PF12840.2 EEQ76987.1 - 0.051 13.3 0.0 0.22 11.3 0.0 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1737 PF08410.5 EEQ76987.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) Sld5 PF05916.6 EEQ76988.1 - 5.6e-11 42.6 0.1 1.1e-10 41.8 0.1 1.6 1 1 0 1 1 1 1 GINS complex protein Rhodanese PF00581.15 EEQ76989.1 - 2.5e-14 53.6 0.0 5.4e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain F-box-like PF12937.2 EEQ76992.1 - 1.1e-06 28.2 0.1 2.8e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ76992.1 - 0.071 12.7 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 F-box domain SapA PF02199.10 EEQ76992.1 - 0.087 12.5 0.1 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Saposin A-type domain PRANC PF09372.5 EEQ76992.1 - 0.17 11.8 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 PRANC domain Iso_dh PF00180.15 EEQ76993.1 - 6.3e-49 166.7 0.0 9e-46 156.4 0.0 2.0 2 0 0 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase adh_short PF00106.20 EEQ76994.1 - 3.7e-13 49.7 0.1 6.2e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ76994.1 - 1.4e-05 24.8 0.1 2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EEQ76994.1 - 0.0065 15.4 0.2 0.83 8.5 0.0 2.3 2 1 0 2 2 2 2 Male sterility protein DUF1776 PF08643.5 EEQ76994.1 - 0.0077 15.4 0.1 0.0097 15.0 0.1 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EEQ76994.1 - 0.037 13.4 0.0 0.072 12.5 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family AIB PF15334.1 EEQ76995.1 - 0.06 12.4 0.0 0.067 12.2 0.0 1.1 1 0 0 1 1 1 0 Aurora kinase A and ninein interacting protein Hydrolase PF00702.21 EEQ76995.1 - 0.088 13.1 0.1 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Peptidase_C15 PF01470.12 EEQ76996.1 - 1.4e-12 47.9 0.0 6.3e-05 22.8 0.0 3.1 2 1 0 2 2 2 2 Pyroglutamyl peptidase Med3 PF11593.3 EEQ76996.1 - 6.3e-05 22.3 0.0 0.00012 21.4 0.0 1.4 1 1 0 1 1 1 1 Mediator complex subunit 3 fungal DUF605 PF04652.11 EEQ76996.1 - 0.21 10.9 10.8 0.3 10.4 7.5 1.2 1 0 0 1 1 1 0 Vta1 like Menin PF05053.8 EEQ76996.1 - 0.37 8.9 2.2 0.45 8.6 1.5 1.1 1 0 0 1 1 1 0 Menin Shisa PF13908.1 EEQ76996.1 - 0.43 10.7 6.4 0.68 10.0 4.4 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Pex14_N PF04695.8 EEQ76996.1 - 3.7 7.6 9.6 7.9 6.5 6.7 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2360 PF10152.4 EEQ76996.1 - 5.5 7.2 7.3 9.9 6.4 5.1 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Mad3_BUB1_I PF08311.7 EEQ76999.1 - 1.9e-43 147.2 0.0 3e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EEQ76999.1 - 3.3e-09 36.2 0.0 1.9e-08 33.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Mad3_BUB1_II PF08171.6 EEQ76999.1 - 0.0017 18.1 0.0 0.0068 16.2 0.0 2.1 1 1 0 1 1 1 1 Mad3/BUB1 homology region 2 AP_endonuc_2 PF01261.19 EEQ77001.1 - 5.7e-26 91.1 0.0 8e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF4442 PF14539.1 EEQ77001.1 - 0.02 14.8 0.3 0.041 13.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) GOLD_2 PF13897.1 EEQ77001.1 - 0.99 9.6 4.5 0.42 10.8 1.0 2.0 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking DNA_pol_phi PF04931.8 EEQ77002.1 - 4.2e-53 180.2 44.5 1.8e-48 164.9 27.9 3.1 2 1 0 2 2 2 2 DNA polymerase phi RRN3 PF05327.6 EEQ77002.1 - 0.1 10.6 15.8 0.26 9.3 10.9 1.7 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 MT0933_antitox PF14013.1 EEQ77003.1 - 4.1 7.5 6.9 38 4.4 4.7 2.6 1 1 0 1 1 1 0 MT0933-like antitoxin protein TPT PF03151.11 EEQ77004.1 - 1.4e-29 102.7 9.0 1.4e-29 102.7 6.2 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EEQ77004.1 - 2.1e-05 24.5 34.1 0.0064 16.5 11.1 2.8 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EEQ77004.1 - 3.4e-05 22.9 17.3 4.5e-05 22.5 11.5 1.4 1 1 0 1 1 1 1 UAA transporter family REV PF00424.13 EEQ77004.1 - 0.17 11.8 2.3 0.35 10.7 1.6 1.4 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) AD PF09793.4 EEQ77005.1 - 3.2e-27 94.1 0.0 6.8e-27 93.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain RP-C_C PF11800.3 EEQ77005.1 - 0.17 11.5 4.3 0.26 10.9 3.0 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region 6PGD PF00393.14 EEQ77006.1 - 4.9e-133 442.7 0.0 6e-133 442.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EEQ77006.1 - 3e-51 173.5 0.0 5.2e-51 172.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase RRM_1 PF00076.17 EEQ77007.1 - 1.1e-16 60.2 0.0 1.9e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ77007.1 - 4.2e-10 39.4 0.0 7.8e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ77007.1 - 0.00065 19.4 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA-synt_1b PF00579.20 EEQ77009.1 - 1.1e-17 64.1 0.0 3.3e-13 49.4 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (W and Y) PRANC PF09372.5 EEQ77010.1 - 0.063 13.2 0.1 0.095 12.6 0.0 1.4 1 1 0 1 1 1 0 PRANC domain 5-FTHF_cyc-lig PF01812.15 EEQ77011.1 - 0.04 13.6 0.1 0.044 13.5 0.1 1.2 1 0 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family ATP-synt_F6 PF05511.6 EEQ77011.1 - 0.052 13.4 0.2 0.066 13.1 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 LRS4 PF10422.4 EEQ77011.1 - 0.1 11.9 0.2 0.51 9.6 0.1 1.7 1 1 1 2 2 2 0 Monopolin complex subunit LRS4 CCDC92 PF14916.1 EEQ77012.1 - 0.0058 16.1 2.4 0.019 14.5 1.6 1.9 1 0 0 1 1 1 1 Coiled-coil domain of unknown function YlqD PF11068.3 EEQ77012.1 - 0.018 15.0 1.5 0.034 14.1 1.1 1.4 1 0 0 1 1 1 0 YlqD protein V-SNARE PF05008.10 EEQ77012.1 - 0.02 15.0 0.8 0.039 14.1 0.5 1.4 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Med4 PF10018.4 EEQ77012.1 - 0.15 11.4 0.9 0.25 10.7 0.6 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Fzo_mitofusin PF04799.8 EEQ77012.1 - 0.17 11.2 0.8 0.29 10.5 0.6 1.3 1 0 0 1 1 1 0 fzo-like conserved region IncA PF04156.9 EEQ77012.1 - 0.18 11.3 4.8 0.14 11.6 2.2 1.6 2 0 0 2 2 2 0 IncA protein TMF_DNA_bd PF12329.3 EEQ77012.1 - 0.23 11.2 4.1 0.43 10.4 2.8 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding GrpE PF01025.14 EEQ77012.1 - 0.24 10.9 1.2 0.37 10.3 0.8 1.2 1 0 0 1 1 1 0 GrpE bZIP_1 PF00170.16 EEQ77012.1 - 1.2 9.1 4.4 2.4 8.1 1.7 2.2 2 0 0 2 2 2 0 bZIP transcription factor NIT PF08376.5 EEQ77014.1 - 0.019 14.4 0.1 0.033 13.7 0.1 1.3 1 0 0 1 1 1 0 Nitrate and nitrite sensing RLL PF10036.4 EEQ77014.1 - 0.076 12.4 0.1 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative carnitine deficiency-associated protein HpcH_HpaI PF03328.9 EEQ77017.1 - 0.051 12.4 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family DUF3775 PF12616.3 EEQ77019.1 - 0.12 12.2 0.2 0.24 11.2 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3775) ABC_tran_2 PF12848.2 EEQ77023.1 - 0.13 12.1 3.1 0.43 10.4 0.4 2.4 2 0 0 2 2 2 0 ABC transporter HR1 PF02185.11 EEQ77023.1 - 0.16 11.6 4.6 0.12 12.1 1.7 1.8 2 0 0 2 2 2 0 Hr1 repeat DUF4349 PF14257.1 EEQ77023.1 - 0.26 10.5 2.8 0.83 8.8 1.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DivIC PF04977.10 EEQ77023.1 - 1.5 8.3 5.5 1.9 8.0 3.0 1.8 2 0 0 2 2 2 0 Septum formation initiator bZIP_2 PF07716.10 EEQ77023.1 - 1.9 8.3 10.2 4.5 7.1 7.1 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Amidase PF01425.16 EEQ77024.1 - 9.4e-82 275.1 0.0 2.4e-79 267.2 0.0 2.1 1 1 0 1 1 1 1 Amidase 2OG-FeII_Oxy_2 PF13532.1 EEQ77025.1 - 9.9e-33 113.6 0.0 1e-31 110.2 0.0 2.0 1 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 EEQ77026.1 - 1.6e-70 237.2 0.0 2e-70 236.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ77026.1 - 1.2e-30 106.4 0.0 1.6e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ77026.1 - 0.00018 20.5 0.0 0.00032 19.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEQ77026.1 - 0.006 16.3 0.0 0.0098 15.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EEQ77026.1 - 0.012 14.4 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 EEQ77026.1 - 0.094 11.7 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_tran PF00005.22 EEQ77028.1 - 1.9e-49 167.4 0.1 1.4e-25 90.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EEQ77028.1 - 7.9e-29 100.7 40.4 1.5e-20 73.5 12.2 2.5 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 EEQ77028.1 - 1.7e-23 84.0 0.5 7.1e-05 22.9 0.0 5.0 5 0 0 5 5 5 4 AAA domain AAA_29 PF13555.1 EEQ77028.1 - 5.4e-11 41.8 1.5 1.3e-05 24.6 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EEQ77028.1 - 2.3e-10 40.1 0.1 5.9e-06 25.6 0.0 3.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EEQ77028.1 - 6.6e-09 36.3 2.1 0.0029 17.9 0.1 2.4 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EEQ77028.1 - 2.2e-05 23.7 0.6 0.062 12.4 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ABC2_membrane PF01061.19 EEQ77028.1 - 0.00011 21.4 11.7 0.00011 21.4 8.1 3.3 3 1 0 3 3 2 1 ABC-2 type transporter AAA_16 PF13191.1 EEQ77028.1 - 0.0002 21.4 0.4 0.46 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.1 EEQ77028.1 - 0.0011 18.0 0.0 0.16 11.0 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.1 EEQ77028.1 - 0.0025 17.4 2.4 2.3 7.7 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EEQ77028.1 - 0.0026 17.1 0.4 1.8 7.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain MutS_V PF00488.16 EEQ77028.1 - 0.0054 16.1 0.1 1.3 8.3 0.1 3.0 3 0 0 3 3 3 1 MutS domain V AAA_28 PF13521.1 EEQ77028.1 - 0.0068 16.3 0.0 0.59 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EEQ77028.1 - 0.031 13.7 0.5 0.082 12.3 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family KdpC PF02669.10 EEQ77028.1 - 0.031 13.9 0.3 0.084 12.5 0.2 1.7 1 0 0 1 1 1 0 K+-transporting ATPase, c chain AAA_22 PF13401.1 EEQ77028.1 - 0.061 13.4 0.6 12 6.0 0.2 2.7 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EEQ77028.1 - 0.075 12.4 0.7 11 5.4 0.1 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 EEQ77028.1 - 0.079 12.0 1.0 4.6 6.2 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin AAA_19 PF13245.1 EEQ77028.1 - 0.096 12.4 3.6 9.3 6.0 0.1 3.1 3 0 0 3 3 3 0 Part of AAA domain AAA_10 PF12846.2 EEQ77028.1 - 0.11 11.9 0.8 8.5 5.7 0.2 2.3 2 0 0 2 2 2 0 AAA-like domain SbcCD_C PF13558.1 EEQ77028.1 - 0.16 11.9 0.2 13 5.7 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EEQ77028.1 - 0.17 11.7 0.3 19 5.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 EEQ77028.1 - 0.33 9.3 0.3 3.9 5.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 EEQ77028.1 - 0.72 8.4 0.0 5.4 5.5 0.1 2.0 2 0 0 2 2 2 0 G-protein alpha subunit AA_permease_2 PF13520.1 EEQ77029.1 - 1.2e-58 198.7 44.2 1.5e-58 198.3 30.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ77029.1 - 4e-13 48.5 39.2 5.3e-13 48.1 27.1 1.1 1 0 0 1 1 1 1 Amino acid permease NMT1 PF09084.6 EEQ77030.1 - 6.6e-77 257.9 0.0 8.2e-77 257.6 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EEQ77030.1 - 2.2e-07 30.5 0.0 0.0077 15.6 0.0 2.7 2 1 0 3 3 3 2 NMT1-like family PBP_like PF12727.2 EEQ77030.1 - 0.026 13.4 0.0 0.56 9.1 0.0 2.2 2 0 0 2 2 2 0 PBP superfamily domain Antifungal_pept PF11410.3 EEQ77031.1 - 5e-06 26.4 1.1 5e-06 26.4 0.7 1.9 3 0 0 3 3 3 1 Antifungal peptide F_bP_aldolase PF01116.15 EEQ77033.1 - 1.6e-79 267.0 0.0 1.8e-79 266.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Fer2_3 PF13085.1 EEQ77034.1 - 2.8e-32 110.8 0.0 4.4e-32 110.1 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EEQ77034.1 - 6.9e-10 39.1 5.7 6.9e-10 39.1 4.0 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EEQ77034.1 - 9.6e-09 35.1 4.0 9.6e-09 35.1 2.8 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EEQ77034.1 - 5e-05 23.6 5.7 0.00029 21.2 0.8 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EEQ77034.1 - 0.00052 20.2 4.0 0.04 14.1 0.2 3.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EEQ77034.1 - 0.00054 19.7 4.0 0.00054 19.7 2.8 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EEQ77034.1 - 0.0036 17.6 5.0 0.0036 17.6 3.5 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EEQ77034.1 - 0.0052 16.5 0.4 0.0052 16.5 0.3 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DPBB_1 PF03330.13 EEQ77035.1 - 1.9e-08 34.1 0.5 3.7e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EEQ77035.1 - 0.0017 17.9 0.1 0.003 17.2 0.1 1.3 1 0 0 1 1 1 1 Barwin family Sec1 PF00995.18 EEQ77035.1 - 0.17 10.4 0.0 0.22 10.0 0.0 1.1 1 0 0 1 1 1 0 Sec1 family ThiF PF00899.16 EEQ77036.1 - 2.4e-39 134.2 0.0 4e-39 133.5 0.0 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EEQ77036.1 - 7.6e-25 86.3 0.1 1.6e-24 85.2 0.1 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EEQ77036.1 - 8.9e-08 32.4 0.0 4.1e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 Rhodanese-like domain FlxA PF14282.1 EEQ77036.1 - 0.0016 18.3 3.1 0.0016 18.3 2.2 2.7 2 0 0 2 2 2 1 FlxA-like protein Shikimate_DH PF01488.15 EEQ77036.1 - 0.0031 17.6 0.1 0.0068 16.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 EEQ77036.1 - 0.078 11.8 2.5 0.045 12.6 0.3 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EEQ77036.1 - 0.59 9.1 4.1 1.2 8.0 2.8 1.4 1 0 0 1 1 1 0 FAD binding domain SLX9 PF15341.1 EEQ77037.1 - 1.3e-36 125.6 8.3 1.3e-36 125.6 5.7 1.5 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 CDK5_activator PF03261.10 EEQ77037.1 - 0.0035 16.7 9.3 0.0045 16.3 6.4 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 5 activator protein DUF3022 PF11226.3 EEQ77037.1 - 0.029 14.2 0.9 2.6 7.9 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3022) DUF1917 PF08939.5 EEQ77037.1 - 0.084 12.6 2.7 0.11 12.1 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) NAD_Gly3P_dh_N PF01210.18 EEQ77038.1 - 7.9e-46 155.6 0.0 1.3e-45 154.9 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EEQ77038.1 - 1.1e-43 148.4 0.7 2.4e-43 147.4 0.3 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus hDGE_amylase PF14701.1 EEQ77039.1 - 8e-176 585.0 0.0 1e-175 584.6 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EEQ77039.1 - 2e-114 382.1 0.0 3.2e-114 381.5 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EEQ77039.1 - 1.2e-88 296.7 0.0 1.7e-88 296.1 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EEQ77039.1 - 2.4e-19 68.9 0.0 6.5e-19 67.5 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 EEQ77039.1 - 0.0078 15.6 0.0 0.8 9.0 0.0 2.2 2 0 0 2 2 2 2 Alpha amylase, catalytic domain DUF221 PF02714.10 EEQ77040.1 - 1.6e-75 254.0 20.8 1.1e-54 185.5 9.0 2.6 3 0 0 3 3 3 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 EEQ77040.1 - 9.3e-30 103.2 1.9 9.3e-30 103.2 1.3 3.2 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EEQ77040.1 - 9.9e-24 83.6 0.5 2e-23 82.6 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 EEQ77040.1 - 0.015 15.2 0.0 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DAHP_synth_1 PF00793.15 EEQ77041.1 - 4.2e-100 333.9 0.0 5.3e-100 333.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Cytochrom_C1 PF02167.10 EEQ77043.1 - 6.1e-81 271.2 0.0 8.7e-81 270.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrom_C PF00034.16 EEQ77043.1 - 0.04 14.7 0.4 0.15 12.8 0.1 2.2 2 1 0 2 2 2 0 Cytochrome c Cytochrome_CBB3 PF13442.1 EEQ77043.1 - 0.059 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III SbcCD_C PF13558.1 EEQ77043.1 - 0.095 12.6 0.4 0.22 11.4 0.3 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.24 EEQ77044.1 - 7.2e-32 110.3 0.0 1.1e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEQ77044.1 - 8.2e-07 29.2 0.0 3.5e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EEQ77044.1 - 1e-06 28.3 0.1 0.015 14.6 0.0 2.3 1 1 1 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EEQ77044.1 - 3.2e-06 27.0 0.1 0.00043 20.0 0.0 2.2 1 1 0 1 1 1 1 Archaeal ATPase AAA_17 PF13207.1 EEQ77044.1 - 9.2e-06 26.4 0.0 2.3e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EEQ77044.1 - 2.2e-05 24.1 0.0 4.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEQ77044.1 - 2.9e-05 24.3 0.0 5.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEQ77044.1 - 4.4e-05 23.5 0.3 0.00018 21.5 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EEQ77044.1 - 0.00019 21.3 0.0 0.00037 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EEQ77044.1 - 0.00021 20.9 0.0 0.00081 19.0 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 EEQ77044.1 - 0.00044 19.7 0.0 0.00085 18.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.1 EEQ77044.1 - 0.00045 20.1 0.1 0.0019 18.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ77044.1 - 0.0018 17.9 0.3 0.0073 16.0 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 EEQ77044.1 - 0.0018 18.3 0.3 0.0039 17.3 0.0 1.8 2 0 0 2 2 1 1 RNA helicase RuvB_N PF05496.7 EEQ77044.1 - 0.0035 16.4 0.1 0.022 13.7 0.0 2.1 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EEQ77044.1 - 0.0037 16.9 0.1 0.012 15.3 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_5 PF07728.9 EEQ77044.1 - 0.0049 16.5 0.5 0.02 14.6 0.4 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EEQ77044.1 - 0.013 15.4 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EEQ77044.1 - 0.015 14.7 0.0 0.035 13.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EEQ77044.1 - 0.021 14.0 0.9 0.21 10.7 0.0 2.5 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 EEQ77044.1 - 0.023 14.6 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 EEQ77044.1 - 0.03 13.4 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Kunitz_legume PF00197.13 EEQ77044.1 - 0.04 13.4 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Trypsin and protease inhibitor DUF815 PF05673.8 EEQ77044.1 - 0.044 12.7 0.0 0.11 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TIP49 PF06068.8 EEQ77044.1 - 0.046 12.4 0.0 0.1 11.2 0.0 1.5 2 0 0 2 2 2 0 TIP49 C-terminus DUF2075 PF09848.4 EEQ77044.1 - 0.047 12.6 0.0 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 EEQ77044.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EEQ77044.1 - 0.072 12.6 0.0 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 EEQ77044.1 - 0.089 11.7 0.1 0.68 8.8 0.0 2.1 1 1 2 3 3 3 0 KAP family P-loop domain MobB PF03205.9 EEQ77044.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.5 EEQ77044.1 - 0.15 11.2 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Sec10 PF07393.6 EEQ77045.1 - 1.1e-160 536.2 0.3 1.3e-160 535.9 0.2 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 CAP PF00188.21 EEQ77046.1 - 1.4e-19 70.7 5.2 1.9e-19 70.3 3.6 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family WD40 PF00400.27 EEQ77047.1 - 5.6e-85 276.4 20.4 1e-14 53.7 0.0 8.4 8 1 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 EEQ77047.1 - 5.4e-11 42.5 0.0 0.0002 21.0 0.0 3.7 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EEQ77047.1 - 8e-07 27.5 9.5 0.22 9.6 0.1 5.6 3 3 2 5 5 5 4 Nucleoporin Nup120/160 NLE PF08154.7 EEQ77047.1 - 1.1e-06 28.5 0.0 2.3e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain DUF1652 PF07865.6 EEQ77047.1 - 0.12 12.0 0.0 31 4.2 0.0 3.5 5 0 0 5 5 5 0 Protein of unknown function (DUF1652) MutS_V PF00488.16 EEQ77048.1 - 5.1e-77 258.4 0.2 7.5e-77 257.8 0.1 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EEQ77048.1 - 1e-30 107.0 2.0 1e-30 107.0 1.4 2.0 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 EEQ77048.1 - 1.3e-10 41.5 0.1 2.8e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EEQ77048.1 - 3.9e-05 23.7 0.0 0.00019 21.5 0.0 2.2 1 0 0 1 1 1 1 MutS family domain IV Epsilon_antitox PF08998.6 EEQ77048.1 - 0.002 18.0 0.2 0.0063 16.4 0.1 1.8 1 0 0 1 1 1 1 Bacterial epsilon antitoxin zf-C3HC4_3 PF13920.1 EEQ77049.1 - 1.5e-06 27.7 8.6 1.5e-06 27.7 5.9 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Mito_fiss_reg PF05308.6 EEQ77049.1 - 0.15 11.4 5.2 0.3 10.4 3.6 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF221 PF02714.10 EEQ77050.1 - 1.3e-108 362.7 23.5 2e-108 362.1 16.3 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF3779 PF12621.3 EEQ77050.1 - 5.4e-29 99.9 0.7 1.1e-28 98.9 0.5 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EEQ77050.1 - 5.4e-20 71.7 1.5 9.9e-20 70.8 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_5 PF13893.1 EEQ77050.1 - 0.13 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AsnA PF03590.10 EEQ77051.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Aspartate-ammonia ligase NAD_binding_2 PF03446.10 EEQ77052.1 - 7.3e-20 71.4 0.1 1.3e-19 70.6 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EEQ77052.1 - 2e-08 34.5 0.1 3.5e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EEQ77052.1 - 1.6e-05 24.7 0.1 3.8e-05 23.4 0.1 1.8 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EEQ77052.1 - 0.00014 21.3 0.0 0.00024 20.5 0.0 1.5 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EEQ77052.1 - 0.00031 20.8 0.0 0.00048 20.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EEQ77052.1 - 0.00037 20.1 0.0 0.00057 19.5 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EEQ77052.1 - 0.018 14.1 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DmpG_comm PF07836.6 EEQ77052.1 - 0.092 12.1 0.1 0.24 10.8 0.1 1.6 1 0 0 1 1 1 0 DmpG-like communication domain TrkA_N PF02254.13 EEQ77052.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain SWIB PF02201.13 EEQ77053.1 - 3.5e-23 81.0 0.1 6.2e-23 80.2 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 EEQ77053.1 - 5e-13 48.5 0.2 1.4e-12 47.1 0.2 1.8 1 0 0 1 1 1 1 DEK C terminal domain eIF2A PF08662.6 EEQ77054.1 - 1.8e-38 132.2 5.3 1.9e-36 125.6 1.4 4.0 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A RRM_5 PF13893.1 EEQ77054.1 - 6e-05 22.8 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EEQ77054.1 - 0.00038 20.2 0.3 0.37 10.7 0.0 4.4 5 0 0 5 5 5 1 WD domain, G-beta repeat RRM_1 PF00076.17 EEQ77054.1 - 0.0024 17.4 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ77054.1 - 0.012 15.5 0.0 0.037 13.9 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PRP3 PF08572.5 EEQ77054.1 - 0.013 14.8 0.4 0.029 13.7 0.3 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) DLH PF01738.13 EEQ77055.1 - 1.9e-34 118.8 0.1 2e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EEQ77055.1 - 2.3e-08 33.9 0.0 2.9e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ77055.1 - 3.8e-05 23.6 0.0 0.00076 19.4 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ77055.1 - 0.059 12.9 0.0 0.34 10.4 0.0 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold Oxidored_FMN PF00724.15 EEQ77057.1 - 0.021 13.8 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family BCS1_N PF08740.6 EEQ77059.1 - 2.8e-10 40.1 0.4 4.1e-10 39.5 0.2 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EEQ77059.1 - 9.8e-09 35.5 0.0 2.1e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEQ77059.1 - 1e-05 26.3 0.1 4.8e-05 24.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEQ77059.1 - 0.00077 19.7 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEQ77059.1 - 0.00089 18.9 0.0 0.002 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEQ77059.1 - 0.0011 19.1 1.0 0.043 13.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EEQ77059.1 - 0.0019 17.2 0.0 0.0028 16.7 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EEQ77059.1 - 0.0047 16.8 0.3 0.089 12.7 0.1 2.3 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.8 EEQ77059.1 - 0.0069 15.1 0.0 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EEQ77059.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EEQ77059.1 - 0.017 14.5 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EEQ77059.1 - 0.018 14.8 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EEQ77059.1 - 0.023 14.0 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 EEQ77059.1 - 0.024 14.6 0.1 0.078 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Proteasome_A_N PF10584.4 EEQ77059.1 - 0.032 13.5 0.1 0.094 12.0 0.0 1.8 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature DUF815 PF05673.8 EEQ77059.1 - 0.061 12.2 0.0 0.097 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 EEQ77059.1 - 0.082 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EEQ77059.1 - 0.093 12.9 0.0 0.25 11.5 0.0 1.9 1 1 0 1 1 1 0 RNA helicase Vac_ImportDeg PF09783.4 EEQ77059.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Vacuolar import and degradation protein Zeta_toxin PF06414.7 EEQ77059.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin FAD_binding_3 PF01494.14 EEQ77063.1 - 6.6e-11 41.8 0.0 1.8e-10 40.4 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EEQ77063.1 - 0.0011 17.9 0.0 0.0018 17.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein ketoacyl-synt PF00109.21 EEQ77065.1 - 0.11 12.0 0.1 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain HgmA PF04209.8 EEQ77066.1 - 2.1e-184 612.8 0.0 2.5e-184 612.6 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase TPR_11 PF13414.1 EEQ77067.1 - 0.012 15.2 1.1 0.032 13.8 0.1 2.3 2 0 0 2 2 2 0 TPR repeat Glyoxalase PF00903.20 EEQ77068.1 - 7.4e-19 67.9 0.2 6.3e-16 58.5 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EEQ77068.1 - 1e-12 47.9 0.1 7.3e-06 25.9 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EEQ77068.1 - 1.2e-08 35.4 0.0 0.007 16.9 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 EEQ77068.1 - 0.00061 19.7 0.0 0.51 10.2 0.0 2.7 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EEQ77068.1 - 0.00081 19.3 0.1 0.0022 17.9 0.1 1.8 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal adh_short PF00106.20 EEQ77069.1 - 8.2e-05 22.5 1.1 0.015 15.2 0.1 2.4 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ77069.1 - 0.0075 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ77069.1 - 0.027 14.1 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 KR domain BTB PF00651.26 EEQ77071.1 - 0.00064 19.6 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain GFRP PF06399.8 EEQ77071.1 - 0.13 11.8 0.0 0.37 10.4 0.0 1.7 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) COX15-CtaA PF02628.10 EEQ77072.1 - 1.1e-93 313.3 11.3 1.4e-93 313.1 7.8 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein zf-B_box PF00643.19 EEQ77073.1 - 0.0047 16.7 4.0 0.0081 16.0 2.8 1.4 1 0 0 1 1 1 1 B-box zinc finger zf-RING_4 PF14570.1 EEQ77073.1 - 0.032 13.7 3.8 0.063 12.8 2.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_2 PF14445.1 EEQ77073.1 - 0.044 13.7 4.4 0.085 12.8 3.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 zf-RanBP PF00641.13 EEQ77073.1 - 0.17 10.9 4.8 0.38 9.9 3.3 1.6 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others tRNA-synt_2 PF00152.15 EEQ77074.1 - 5.1e-92 308.2 1.3 7.3e-92 307.6 0.9 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EEQ77074.1 - 3.8e-12 45.8 0.1 9.2e-11 41.4 0.0 2.6 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EEQ77074.1 - 6.4e-06 25.5 0.1 0.012 14.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Dynamin_N PF00350.18 EEQ77075.1 - 7.9e-23 81.0 0.0 2.3e-22 79.5 0.0 1.9 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EEQ77075.1 - 2.7e-16 59.2 1.0 4.5e-13 48.6 0.1 2.2 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 EEQ77075.1 - 3.6e-08 33.1 0.7 1.1e-07 31.5 0.5 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EEQ77075.1 - 0.0045 16.9 0.0 0.095 12.6 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEQ77075.1 - 0.0072 16.8 0.0 0.023 15.1 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein IIGP PF05049.8 EEQ77075.1 - 0.04 12.7 0.0 2.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) NTP_transferase PF00483.18 EEQ77076.1 - 1.2e-22 80.4 0.0 1.5e-19 70.2 0.0 2.2 2 0 0 2 2 2 2 Nucleotidyl transferase Hexapep PF00132.19 EEQ77076.1 - 1.9e-08 33.4 9.5 1e-06 27.9 0.2 4.0 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EEQ77076.1 - 0.0003 20.9 0.0 0.00085 19.4 0.0 1.7 2 0 0 2 2 2 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EEQ77076.1 - 0.047 13.2 3.3 0.097 12.2 0.1 2.7 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase DUF2968 PF11180.3 EEQ77076.1 - 0.093 12.0 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) NKAIN PF05640.9 EEQ77078.1 - 0.013 14.4 2.7 0.015 14.2 1.9 1.0 1 0 0 1 1 1 0 Na,K-Atpase Interacting protein GWT1 PF06423.7 EEQ77078.1 - 0.055 13.5 0.4 0.08 13.0 0.3 1.2 1 0 0 1 1 1 0 GWT1 GHMP_kinases_N PF00288.21 EEQ77078.1 - 0.68 10.0 4.6 9.2 6.4 2.0 2.2 2 0 0 2 2 2 0 GHMP kinases N terminal domain Bys1 PF04681.7 EEQ77079.1 - 4.6e-16 58.8 0.0 5.9e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein FAD_binding_6 PF00970.19 EEQ77081.1 - 1.5e-06 28.2 0.0 6.1e-05 23.0 0.0 2.7 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain FAD_binding_9 PF08021.6 EEQ77081.1 - 0.039 13.9 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain zf-RING_2 PF13639.1 EEQ77082.1 - 1.5e-08 34.2 2.4 2.4e-08 33.6 1.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EEQ77082.1 - 2.2e-05 24.4 0.4 4.9e-05 23.3 0.2 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EEQ77082.1 - 0.0024 17.6 0.4 0.0037 17.0 0.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EEQ77082.1 - 0.0025 17.8 1.7 0.0042 17.0 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ77082.1 - 0.26 10.9 1.6 1.4 8.6 1.1 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Atx10homo_assoc PF09759.4 EEQ77083.1 - 3.6e-30 103.7 0.7 1.2e-29 102.0 0.1 2.1 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain ketoacyl-synt PF00109.21 EEQ77084.1 - 0.017 14.5 0.8 0.026 14.0 0.6 1.2 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Phosducin PF02114.11 EEQ77085.1 - 1.3e-14 53.5 0.0 2.2e-13 49.5 0.0 2.1 1 1 0 1 1 1 1 Phosducin Clathrin_lg_ch PF01086.12 EEQ77085.1 - 0.23 11.3 5.0 0.41 10.5 3.5 1.5 1 1 0 1 1 1 0 Clathrin light chain YTH PF04146.10 EEQ77087.1 - 1.6e-32 112.0 0.0 2.5e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain Pro_CA PF00484.14 EEQ77088.1 - 5.4e-44 149.8 0.1 6.8e-44 149.5 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Velvet PF11754.3 EEQ77091.1 - 3.9e-60 202.9 0.3 1.3e-59 201.2 0.2 1.8 1 1 0 1 1 1 1 Velvet factor MOZ_SAS PF01853.13 EEQ77094.1 - 2.8e-79 264.7 0.0 3.9e-79 264.2 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 EEQ77094.1 - 0.06 13.0 15.1 0.016 14.8 7.6 2.1 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.17 EEQ77094.1 - 0.11 12.2 3.6 0.25 11.0 2.5 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Acetyltransf_2 PF00797.12 EEQ77096.1 - 1.6e-39 135.9 0.0 1.9e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase Methyltransf_6 PF03737.10 EEQ77097.1 - 5.8e-22 78.2 0.0 9.3e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase AFOR_N PF02730.10 EEQ77097.1 - 0.045 13.1 0.0 0.064 12.5 0.0 1.2 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain Thiolase_N PF00108.18 EEQ77098.1 - 3.6e-79 265.4 1.9 6.2e-79 264.6 1.3 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EEQ77098.1 - 9.2e-44 147.8 0.2 1.8e-43 146.8 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 EEQ77098.1 - 0.018 15.0 0.0 0.048 13.6 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.21 EEQ77098.1 - 0.086 12.3 4.8 0.093 12.1 0.4 2.6 2 1 1 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain MFS_1 PF07690.11 EEQ77100.1 - 3.7e-25 88.4 30.4 5.1e-25 87.9 21.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily WCOR413 PF05562.6 EEQ77100.1 - 0.058 12.9 1.3 0.12 11.8 0.9 1.5 1 0 0 1 1 1 0 Cold acclimation protein WCOR413 Drf_GBD PF06371.8 EEQ77102.1 - 9.8e-18 64.1 0.0 8.8e-11 41.5 0.0 2.4 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Snf7 PF03357.16 EEQ77103.1 - 1.2e-41 141.9 16.3 1.4e-41 141.6 11.3 1.0 1 0 0 1 1 1 1 Snf7 DUF4201 PF13870.1 EEQ77103.1 - 0.0013 18.2 6.1 0.0013 18.2 4.3 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) NPV_P10 PF05531.7 EEQ77103.1 - 0.011 15.9 6.9 0.2 11.9 0.9 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Zwint PF15556.1 EEQ77103.1 - 0.034 13.3 7.4 0.047 12.9 5.1 1.3 1 0 0 1 1 1 0 ZW10 interactor HHH_2 PF12826.2 EEQ77103.1 - 0.089 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif Reo_sigmaC PF04582.7 EEQ77103.1 - 0.12 11.5 4.3 0.21 10.7 0.4 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF4140 PF13600.1 EEQ77103.1 - 0.4 11.1 5.8 0.67 10.4 0.0 3.2 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Prefoldin_2 PF01920.15 EEQ77103.1 - 0.4 10.4 11.9 0.58 9.9 0.0 3.5 1 1 1 2 2 1 0 Prefoldin subunit DUF4208 PF13907.1 EEQ77103.1 - 0.49 10.6 5.7 0.17 12.1 1.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4208) IncA PF04156.9 EEQ77103.1 - 0.63 9.6 6.8 1.2 8.6 0.5 2.2 2 0 0 2 2 2 0 IncA protein Atg14 PF10186.4 EEQ77103.1 - 0.64 8.9 7.8 0.84 8.5 5.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Laminin_II PF06009.7 EEQ77103.1 - 0.76 9.5 8.0 0.86 9.3 1.1 2.2 1 1 1 2 2 2 0 Laminin Domain II DUF342 PF03961.8 EEQ77103.1 - 0.89 7.8 7.4 0.72 8.1 1.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) BLOC1_2 PF10046.4 EEQ77103.1 - 1.5 8.9 9.2 3.8 7.7 2.1 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Uso1_p115_C PF04871.8 EEQ77103.1 - 1.7 8.5 11.2 4.8 7.1 7.8 1.8 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Prefoldin PF02996.12 EEQ77103.1 - 1.8 8.1 8.8 21 4.7 0.0 3.7 2 1 1 3 3 3 0 Prefoldin subunit SYCE1 PF15233.1 EEQ77103.1 - 3.1 7.7 8.8 29 4.5 6.1 2.1 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 DUF4337 PF14235.1 EEQ77103.1 - 4.4 7.1 8.4 0.65 9.8 1.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) OmpH PF03938.9 EEQ77103.1 - 8.3 6.3 16.3 4.6 7.1 4.8 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) SAPS PF04499.10 EEQ77104.1 - 1.2e-201 670.4 0.0 7.4e-200 664.5 0.0 2.1 2 0 0 2 2 2 2 SIT4 phosphatase-associated protein RRN3 PF05327.6 EEQ77104.1 - 0.32 9.0 1.0 0.5 8.4 0.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RnfC_N PF13375.1 EEQ77105.1 - 0.049 13.3 0.1 7.8 6.2 0.0 2.3 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Complex1_51K PF01512.12 EEQ77106.1 - 5.6e-47 159.2 0.0 9.3e-47 158.5 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EEQ77106.1 - 1.5e-18 65.6 0.7 1.5e-18 65.6 0.5 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EEQ77106.1 - 5.5e-10 38.9 0.0 2.8e-09 36.7 0.0 2.3 2 0 0 2 2 2 1 SLBB domain Nup96 PF12110.3 EEQ77107.1 - 1.1e-89 300.4 0.0 1.5e-89 299.9 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EEQ77107.1 - 8.2e-47 158.5 0.0 1.4e-46 157.8 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EEQ77107.1 - 9.9e-09 35.4 115.7 7.1e-07 29.4 39.8 10.4 4 3 5 9 9 9 3 Nucleoporin FG repeat region AMP-binding PF00501.23 EEQ77108.1 - 3.9e-90 302.2 0.0 5e-90 301.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ77108.1 - 2.4e-24 86.0 0.3 1.7e-20 73.7 0.2 3.2 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain GET2 PF08690.5 EEQ77110.1 - 2.3e-05 23.8 0.1 5.5e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 GET complex subunit GET2 C2 PF00168.25 EEQ77111.1 - 1.2e-21 76.3 0.1 6.7e-15 54.7 0.0 3.4 3 0 0 3 3 3 2 C2 domain U1snRNP70_N PF12220.3 EEQ77111.1 - 3.7 7.9 11.1 7 7.0 0.6 3.2 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal ACC_epsilon PF13822.1 EEQ77113.1 - 2.6 8.4 5.4 20 5.6 0.1 3.2 3 0 0 3 3 3 0 Acyl-CoA carboxylase epsilon subunit IMS PF00817.15 EEQ77114.1 - 5.2e-29 100.9 0.0 9.3e-29 100.1 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EEQ77114.1 - 4.8e-05 23.2 0.0 0.0004 20.3 0.0 2.5 2 1 0 3 3 3 1 impB/mucB/samB family C-terminal domain HHH_5 PF14520.1 EEQ77114.1 - 0.091 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH_8 PF14716.1 EEQ77114.1 - 0.17 12.1 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain TMEM154 PF15102.1 EEQ77114.1 - 0.24 11.1 5.0 0.5 10.0 3.5 1.5 1 0 0 1 1 1 0 TMEM154 protein family Reprolysin_5 PF13688.1 EEQ77116.1 - 2.6e-66 223.3 4.0 2.6e-66 223.3 2.8 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EEQ77116.1 - 5.5e-49 166.5 0.5 1.2e-48 165.3 0.3 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EEQ77116.1 - 5.4e-46 156.8 1.5 1.7e-45 155.2 1.0 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EEQ77116.1 - 1.3e-19 70.9 0.5 1.1e-18 67.9 0.1 2.5 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EEQ77116.1 - 3.4e-18 65.6 36.0 3.4e-18 65.6 25.0 4.7 2 1 2 4 4 4 1 Disintegrin Pep_M12B_propep PF01562.14 EEQ77116.1 - 0.031 14.0 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Reprolysin family propeptide EF-hand_7 PF13499.1 EEQ77117.1 - 3.6e-15 55.8 0.2 1.4e-08 34.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EEQ77117.1 - 1.5e-14 52.0 2.2 3.3e-05 22.8 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EEQ77117.1 - 6.4e-13 47.4 9.3 4.7e-06 26.0 0.1 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 EEQ77117.1 - 2.5e-11 43.0 2.5 4.9e-09 35.6 0.2 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.2 EEQ77117.1 - 0.069 12.8 0.0 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.1 EEQ77117.1 - 0.68 9.3 13.6 0.29 10.5 0.5 3.6 4 0 0 4 4 4 0 EF hand DUF4202 PF13875.1 EEQ77118.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) MgsA_C PF12002.3 EEQ77119.1 - 1.5e-58 197.1 0.1 2.5e-58 196.4 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EEQ77119.1 - 5.3e-14 52.5 0.0 1.2e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EEQ77119.1 - 1.3e-10 40.7 0.0 3.1e-10 39.5 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 EEQ77119.1 - 2.1e-05 24.0 0.0 0.0012 18.3 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 EEQ77119.1 - 3.7e-05 23.8 0.1 0.00013 22.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EEQ77119.1 - 4.5e-05 22.7 0.1 0.048 12.8 0.0 2.2 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEQ77119.1 - 6.4e-05 22.6 0.1 0.0049 16.6 0.0 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EEQ77119.1 - 7.2e-05 22.6 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ77119.1 - 8.3e-05 22.2 0.0 0.00021 20.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activ_2 PF14532.1 EEQ77119.1 - 0.00015 21.8 0.0 0.00034 20.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EEQ77119.1 - 0.0024 17.4 0.0 0.0068 16.0 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 EEQ77119.1 - 0.0041 16.9 0.2 2 8.2 0.0 2.3 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit DUF815 PF05673.8 EEQ77119.1 - 0.0041 16.0 0.0 0.0069 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.1 EEQ77119.1 - 0.0056 16.9 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEQ77119.1 - 0.006 17.3 0.1 0.023 15.4 0.0 1.8 1 1 0 2 2 1 1 AAA domain TIP49 PF06068.8 EEQ77119.1 - 0.0078 14.9 0.0 0.016 13.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus NB-ARC PF00931.17 EEQ77119.1 - 0.018 13.9 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 EEQ77119.1 - 0.019 14.9 0.0 0.27 11.1 0.0 2.3 1 1 1 2 2 2 0 AAA ATPase domain AAA_30 PF13604.1 EEQ77119.1 - 0.036 13.6 0.4 0.1 12.1 0.3 1.7 1 1 0 1 1 1 0 AAA domain SKI PF01202.17 EEQ77119.1 - 0.054 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase Parvo_NS1 PF01057.12 EEQ77119.1 - 0.077 11.8 0.0 0.29 9.9 0.0 1.9 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 Aminotran_1_2 PF00155.16 EEQ77120.1 - 9.8e-69 232.0 0.0 2e-68 230.9 0.0 1.5 1 1 1 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EEQ77120.1 - 0.00012 21.3 0.0 0.00017 20.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EEQ77120.1 - 0.00017 19.9 0.0 0.00028 19.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EEQ77120.1 - 0.0028 16.7 0.0 0.0052 15.8 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EEQ77120.1 - 0.12 11.1 0.1 0.3 9.7 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class-V KH_1 PF00013.24 EEQ77121.1 - 2.4e-43 145.5 16.4 3.8e-15 55.2 1.3 3.6 3 1 1 4 4 4 3 KH domain KH_3 PF13014.1 EEQ77121.1 - 7e-33 111.7 15.6 2.5e-11 42.9 0.1 4.7 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 EEQ77121.1 - 8.8e-14 50.8 1.9 0.0015 18.0 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EEQ77121.1 - 3.7e-09 36.0 1.9 0.018 14.6 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EEQ77121.1 - 0.00022 20.9 4.1 4.9 7.0 0.0 3.6 3 0 0 3 3 3 3 NusA-like KH domain MtrF PF09472.5 EEQ77122.1 - 5.4 6.3 6.1 0.53 9.5 0.5 2.0 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Ald_Xan_dh_C2 PF02738.13 EEQ77124.1 - 8.1e-181 602.0 0.6 4.5e-179 596.2 0.4 2.1 1 1 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EEQ77124.1 - 1.5e-47 161.1 0.0 2.9e-47 160.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 EEQ77124.1 - 1.2e-33 115.1 0.0 3.7e-33 113.5 0.0 1.9 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 EEQ77124.1 - 1.1e-28 98.8 0.1 2.6e-28 97.7 0.0 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.17 EEQ77124.1 - 4.8e-27 94.2 0.0 1.6e-26 92.5 0.0 2.0 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.22 EEQ77124.1 - 2e-08 33.8 0.5 5.7e-08 32.4 0.1 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.12 EEQ77124.1 - 0.013 14.9 0.1 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 DUF218 domain Herpes_gE PF02480.11 EEQ77126.1 - 0.014 13.6 0.0 0.017 13.4 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 EEQ77126.1 - 0.026 13.3 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Tetraspannin PF00335.15 EEQ77126.1 - 0.15 11.3 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Tetraspanin family AAA_17 PF13207.1 EEQ77127.1 - 0.00069 20.4 0.3 0.0015 19.3 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEQ77127.1 - 0.0026 18.0 0.0 0.012 15.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EEQ77127.1 - 0.015 14.8 0.2 0.023 14.2 0.1 1.5 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.22 EEQ77127.1 - 0.019 15.2 0.0 0.041 14.1 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EEQ77127.1 - 0.02 14.3 0.2 0.043 13.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EEQ77127.1 - 0.092 13.0 0.0 0.13 12.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain CPT PF07931.7 EEQ77127.1 - 0.096 12.2 0.2 1 8.9 0.0 2.4 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.1 EEQ77127.1 - 0.13 12.1 0.8 0.27 11.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.18 EEQ77128.1 - 9.7e-38 129.6 0.0 2.2e-33 115.3 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ77128.1 - 0.00015 21.5 0.0 0.00032 20.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AsiA PF09010.5 EEQ77128.1 - 0.18 11.6 0.2 0.4 10.6 0.1 1.5 1 0 0 1 1 1 0 Anti-Sigma Factor A HMG_box PF00505.14 EEQ77129.1 - 4e-23 81.4 0.2 6.6e-23 80.7 0.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EEQ77129.1 - 2e-08 34.4 0.1 3.8e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain Ribosomal_S6e PF01092.14 EEQ77131.1 - 1.6e-59 199.0 0.1 3.5e-59 197.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e Pribosyltran_N PF13793.1 EEQ77132.1 - 8.7e-46 154.4 0.9 5.5e-44 148.6 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EEQ77132.1 - 3.2e-43 147.6 2.3 8.3e-37 126.7 0.7 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EEQ77132.1 - 7.9e-14 51.4 0.4 1.6e-12 47.2 0.3 2.4 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EEQ77132.1 - 0.00095 18.4 0.5 0.0016 17.6 0.3 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF913 PF06025.7 EEQ77133.1 - 1.1e-140 468.7 0.0 1.1e-140 468.7 0.0 3.8 4 0 0 4 4 4 1 Domain of Unknown Function (DUF913) HECT PF00632.20 EEQ77133.1 - 5.4e-96 321.4 0.1 9.2e-96 320.7 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 EEQ77133.1 - 6.6e-85 285.2 4.7 6.6e-85 285.2 3.3 3.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EEQ77133.1 - 1.1e-35 121.8 6.0 1.1e-35 121.8 4.2 4.6 4 1 0 4 4 4 1 Domain of unknown function (DUF4414) An_peroxidase PF03098.10 EEQ77134.1 - 1.9e-78 264.1 0.0 8.2e-68 229.0 0.0 2.1 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.17 EEQ77134.1 - 9.9e-07 27.6 0.1 2.8e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 Steroid_dh PF02544.11 EEQ77135.1 - 9.4e-33 113.1 1.3 1.3e-32 112.6 0.9 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 EEQ77135.1 - 3.1e-07 30.4 2.1 1e-06 28.7 0.3 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 EEQ77135.1 - 1.2e-05 24.7 0.8 1.5e-05 24.3 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) APH PF01636.18 EEQ77136.1 - 5.3e-14 52.5 0.1 6.1e-13 49.0 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ77136.1 - 0.00045 19.8 0.0 0.00064 19.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EEQ77136.1 - 0.2 10.7 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Glyco_transf_34 PF05637.7 EEQ77137.1 - 1.3e-59 201.5 0.0 1.7e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Ribosomal_L28 PF00830.14 EEQ77138.1 - 2.2e-19 69.0 2.2 2.2e-19 69.0 1.5 1.8 2 0 0 2 2 2 1 Ribosomal L28 family TIP49 PF06068.8 EEQ77139.1 - 7.1e-185 614.4 0.0 8.2e-185 614.1 0.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EEQ77139.1 - 2.9e-11 43.7 0.2 2.4e-07 31.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EEQ77139.1 - 3.1e-11 42.7 1.1 8e-07 28.3 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EEQ77139.1 - 1.1e-06 28.7 0.1 0.0044 17.0 0.0 2.5 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EEQ77139.1 - 2.3e-05 24.5 0.1 0.25 11.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EEQ77139.1 - 4.5e-05 23.1 0.1 0.00014 21.5 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EEQ77139.1 - 0.00021 21.3 0.1 0.00046 20.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEQ77139.1 - 0.0009 18.9 0.2 0.19 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EEQ77139.1 - 0.0016 17.5 0.3 0.0039 16.3 0.2 1.6 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EEQ77139.1 - 0.0023 17.4 0.1 1.6 8.1 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 EEQ77139.1 - 0.0023 17.3 0.0 0.0042 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EEQ77139.1 - 0.011 14.8 0.1 0.52 9.4 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EEQ77139.1 - 0.028 13.8 0.1 0.053 12.9 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 EEQ77139.1 - 0.032 13.1 0.0 0.057 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 EEQ77139.1 - 0.037 14.3 0.1 0.25 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EEQ77139.1 - 0.045 12.8 0.4 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 KaiC DnaB_C PF03796.10 EEQ77139.1 - 0.069 12.0 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_17 PF13207.1 EEQ77139.1 - 0.078 13.8 0.0 0.21 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain NAD_binding_8 PF13450.1 EEQ77140.1 - 2.9e-15 56.0 0.1 5.4e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EEQ77140.1 - 1.6e-08 34.1 0.0 6.5e-08 32.0 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EEQ77140.1 - 1.3e-06 27.5 0.1 2e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EEQ77140.1 - 0.00044 20.5 0.1 0.0038 17.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEQ77140.1 - 0.0014 17.5 0.1 0.0023 16.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EEQ77140.1 - 0.0028 17.4 0.1 0.071 12.8 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EEQ77140.1 - 0.0034 15.9 0.1 0.0099 14.3 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EEQ77140.1 - 0.0048 16.0 0.1 0.012 14.7 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EEQ77140.1 - 0.0061 16.4 0.1 0.076 12.8 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.7 EEQ77140.1 - 0.016 14.6 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain FMO-like PF00743.14 EEQ77140.1 - 0.016 13.4 0.1 0.024 12.8 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EEQ77140.1 - 0.022 14.8 0.1 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEQ77140.1 - 0.053 12.3 0.1 0.1 11.4 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 EEQ77140.1 - 0.12 11.3 0.3 0.24 10.4 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase V-SNARE PF05008.10 EEQ77141.1 - 5.8e-21 74.4 5.9 5.8e-21 74.4 4.1 2.0 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EEQ77141.1 - 7.7e-15 54.7 0.5 7.7e-15 54.7 0.3 2.6 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus ApoLp-III PF07464.6 EEQ77141.1 - 0.019 14.9 3.8 0.15 12.0 1.4 2.4 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Phe_tRNA-synt_N PF02912.13 EEQ77141.1 - 0.073 12.8 1.5 10 5.9 0.0 2.5 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF1474 PF07342.6 EEQ77141.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) V_ATPase_I PF01496.14 EEQ77141.1 - 0.84 7.4 5.6 0.35 8.6 1.3 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Histone_HNS PF00816.16 EEQ77141.1 - 2.2 8.8 6.5 0.3 11.5 1.3 1.8 2 0 0 2 2 2 0 H-NS histone family TBCA PF02970.11 EEQ77141.1 - 4.8 7.3 11.2 1.5 8.9 1.9 2.8 3 1 0 3 3 3 0 Tubulin binding cofactor A YqjK PF13997.1 EEQ77141.1 - 8.9 6.5 7.3 1.4 9.1 0.1 2.8 3 0 0 3 3 3 0 YqjK-like protein DUF2407_C PF13373.1 EEQ77142.1 - 6.8e-41 139.4 0.0 9.5e-41 138.9 0.0 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EEQ77142.1 - 1.9e-31 108.1 0.0 1.2e-30 105.5 0.0 2.0 1 1 1 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EEQ77142.1 - 0.00036 19.8 0.0 0.00064 19.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 EEQ77142.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Peptidase_C48 PF02902.14 EEQ77145.1 - 7.1e-18 65.0 0.2 1.2e-17 64.2 0.1 1.4 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain IBV_3C PF03620.8 EEQ77145.1 - 0.0018 18.0 0.0 0.095 12.6 0.0 2.8 3 0 0 3 3 3 1 IBV 3C protein Fe-S_biosyn PF01521.15 EEQ77146.1 - 3.9e-19 68.6 0.0 6e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Hid1 PF12722.2 EEQ77146.1 - 0.53 7.8 7.1 0.67 7.5 4.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pneumo_att_G PF05539.6 EEQ77146.1 - 0.69 9.2 15.7 0.85 8.9 10.9 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G ATP11 PF06644.6 EEQ77146.1 - 1.6 8.2 5.1 2.1 7.7 3.5 1.1 1 0 0 1 1 1 0 ATP11 protein DUF4551 PF15087.1 EEQ77146.1 - 1.8 6.8 11.8 2.2 6.5 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF605 PF04652.11 EEQ77146.1 - 3.1 7.0 23.1 4.2 6.6 16.0 1.1 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 EEQ77146.1 - 3.5 5.7 12.1 4.3 5.4 8.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF1741 PF08427.5 EEQ77147.1 - 7.8e-96 320.1 0.5 3.2e-95 318.1 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) MRG PF05712.8 EEQ77148.1 - 1.7e-56 190.2 0.2 2.6e-56 189.6 0.1 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EEQ77148.1 - 8.2e-09 35.0 3.3 2.2e-08 33.6 2.3 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EEQ77148.1 - 0.28 10.9 3.9 0.23 11.1 1.1 2.1 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Cnl2_NKP2 PF09447.5 EEQ77149.1 - 1.5e-27 95.0 1.6 2.6e-27 94.2 1.1 1.4 1 0 0 1 1 1 1 Cnl2/NKP2 family protein DUF4598 PF15370.1 EEQ77149.1 - 0.046 14.0 0.7 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) KfrA_N PF11740.3 EEQ77149.1 - 0.28 11.6 3.1 1.9 8.9 0.2 2.1 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Ctf8 PF09696.5 EEQ77151.1 - 2.3e-40 137.1 0.0 3.2e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Ctf8 Glyoxalase PF00903.20 EEQ77152.1 - 1.6e-21 76.5 0.0 1.4e-16 60.6 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EEQ77152.1 - 2.8e-12 46.5 0.0 3.1e-06 27.1 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EEQ77152.1 - 2.4e-08 34.5 0.0 3.2e-06 27.7 0.0 2.5 2 1 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_3 PF13468.1 EEQ77152.1 - 2.7e-06 27.3 0.0 0.084 12.7 0.0 3.4 3 1 0 3 3 3 2 Glyoxalase-like domain RabGAP-TBC PF00566.13 EEQ77153.1 - 1.7e-49 168.1 0.1 1.7e-49 168.1 0.1 2.5 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Microtub_assoc PF07989.6 EEQ77153.1 - 0.016 15.0 18.2 0.11 12.2 2.1 4.0 3 1 1 4 4 4 0 Microtubule associated Med9 PF07544.8 EEQ77153.1 - 1.4 8.6 9.8 0.075 12.7 0.5 3.5 4 1 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 PPTA PF01239.17 EEQ77154.1 - 1.3e-31 106.5 12.9 2.5e-07 29.7 0.0 5.7 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Trns_repr_metal PF02583.12 EEQ77154.1 - 0.14 12.4 0.8 0.48 10.6 0.1 2.2 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor WD40 PF00400.27 EEQ77155.1 - 1.8e-11 43.4 13.5 3.1e-07 30.0 0.0 5.7 7 0 0 7 7 7 4 WD domain, G-beta repeat Utp12 PF04003.7 EEQ77156.1 - 3.9e-21 75.0 0.1 7.9e-21 74.0 0.1 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Daxx PF03344.10 EEQ77156.1 - 4.8 5.5 43.8 1.7 7.0 8.4 2.4 2 0 0 2 2 2 0 Daxx Family Bromodomain PF00439.20 EEQ77158.1 - 2.8e-40 136.1 0.1 1.2e-20 73.1 0.1 2.5 2 0 0 2 2 2 2 Bromodomain DUF3573 PF12097.3 EEQ77158.1 - 0.023 13.3 3.3 0.035 12.7 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) HeLo PF14479.1 EEQ77158.1 - 0.21 11.3 3.6 0.53 10.0 2.5 1.7 1 0 0 1 1 1 0 Prion-inhibition and propagation Sulfate_transp PF00916.15 EEQ77159.1 - 2.4e-42 144.8 6.9 2.4e-42 144.8 4.8 2.0 2 0 0 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 EEQ77159.1 - 2.4e-15 56.0 0.0 4.3e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 EEQ77159.1 - 2.1e-11 43.2 0.1 3.6e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 STAS domain Sld5 PF05916.6 EEQ77160.1 - 2.2e-15 56.8 0.0 3.9e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein HMG_box PF00505.14 EEQ77161.1 - 4.3e-11 42.9 1.3 8e-11 42.0 0.9 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box MAT_Alpha1 PF04769.7 EEQ77161.1 - 0.079 12.2 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 PHD PF00628.24 EEQ77167.1 - 2.6e-09 36.6 8.4 5.4e-09 35.6 5.8 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EEQ77167.1 - 0.0017 17.6 4.4 0.0017 17.6 3.0 2.1 2 0 0 2 2 2 1 PHD-finger Rcd1 PF04078.8 EEQ77168.1 - 1.1e-130 434.2 3.0 1.4e-130 433.8 2.1 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Ycf1 PF05758.7 EEQ77168.1 - 0.0095 13.7 0.0 0.014 13.1 0.0 1.3 2 0 0 2 2 2 1 Ycf1 FRQ PF09421.5 EEQ77168.1 - 0.011 13.5 6.0 0.014 13.2 4.2 1.1 1 0 0 1 1 1 0 Frequency clock protein PAT1 PF09770.4 EEQ77168.1 - 0.22 9.7 26.6 0.26 9.4 18.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EEQ77168.1 - 2.1 8.1 25.9 2.9 7.6 18.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 EEQ77168.1 - 4.1 5.4 39.2 4.9 5.2 27.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TMEM51 PF15345.1 EEQ77169.1 - 0.1 12.2 1.9 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 Transmembrane protein 51 TraL PF07178.6 EEQ77169.1 - 0.24 11.4 1.4 13 5.9 0.3 2.3 2 0 0 2 2 2 0 TraL protein MFS_1 PF07690.11 EEQ77173.1 - 6.8e-32 110.5 40.4 6.8e-32 110.5 28.0 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ77173.1 - 6.6e-14 51.0 16.8 9.3e-14 50.5 11.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEQ77173.1 - 2.5e-13 49.4 7.9 2.5e-13 49.4 5.5 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EEQ77173.1 - 0.0052 14.8 0.2 0.0052 14.8 0.1 3.2 4 0 0 4 4 4 1 Organic Anion Transporter Polypeptide (OATP) family Trypsin PF00089.21 EEQ77174.1 - 4.4e-08 32.9 0.0 1e-07 31.8 0.0 1.6 1 1 0 1 1 1 1 Trypsin Glyco_hydro_61 PF03443.9 EEQ77175.1 - 1.7e-84 282.9 0.2 2.1e-84 282.6 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SUI1 PF01253.17 EEQ77176.1 - 1.6e-16 59.8 0.0 3.8e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 Kin17_mid PF10357.4 EEQ77176.1 - 0.074 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein Fungal_trans PF04082.13 EEQ77177.1 - 7.1e-21 74.2 0.7 1.3e-20 73.4 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ77177.1 - 0.00024 20.9 0.8 0.00068 19.4 0.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ERG4_ERG24 PF01222.12 EEQ77178.1 - 2.5e-134 448.0 16.8 2.9e-134 447.8 11.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Velvet PF11754.3 EEQ77180.1 - 4.8e-65 218.9 0.0 8.1e-65 218.2 0.0 1.4 1 0 0 1 1 1 1 Velvet factor PQQ_2 PF13360.1 EEQ77180.1 - 0.0077 15.7 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 PQQ-like domain Pox_A_type_inc PF04508.7 EEQ77181.1 - 0.079 12.7 2.6 0.28 11.0 1.8 2.1 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat MFS_1 PF07690.11 EEQ77182.1 - 5e-35 120.8 27.1 5e-35 120.8 18.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TraL PF07178.6 EEQ77182.1 - 0.32 11.0 0.1 0.32 11.0 0.0 2.6 3 0 0 3 3 3 0 TraL protein DUF373 PF04123.8 EEQ77182.1 - 0.6 9.0 4.0 0.41 9.6 1.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Abhydrolase_3 PF07859.8 EEQ77183.1 - 2.1e-66 223.5 0.2 2.6e-66 223.2 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEQ77183.1 - 1.8e-08 33.9 0.1 5.5e-08 32.2 0.1 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEQ77183.1 - 7e-07 29.0 0.1 1e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EEQ77183.1 - 5.6e-06 25.2 0.0 9.2e-06 24.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EEQ77183.1 - 2.4e-05 23.2 0.7 6.4e-05 21.8 0.5 1.6 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.13 EEQ77183.1 - 0.0055 16.0 0.0 0.026 13.7 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family DHDPS PF00701.17 EEQ77185.1 - 8e-42 142.8 0.0 1.1e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family AP_endonuc_2 PF01261.19 EEQ77185.1 - 0.09 12.0 0.0 0.19 10.9 0.0 1.5 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Ribonuc_L-PSP PF01042.16 EEQ77186.1 - 6e-39 132.5 0.1 6.7e-39 132.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP D-ser_dehydrat PF14031.1 EEQ77187.1 - 4.1e-25 87.8 0.0 8.2e-25 86.8 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EEQ77187.1 - 7.1e-15 55.1 0.0 1.2e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EEQ77189.1 - 4.8e-33 114.3 0.7 1.4e-32 112.8 0.5 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 EEQ77189.1 - 1.7e-15 57.4 0.0 5.8e-15 55.7 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EEQ77189.1 - 7.1e-14 51.0 1.1 3.8e-13 48.7 0.7 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HpaB_N PF11794.3 EEQ77189.1 - 3e-06 26.8 0.3 1.6e-05 24.4 0.2 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_dh_N PF02771.11 EEQ77189.1 - 0.0005 20.6 0.0 0.0014 19.1 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain DUF1540 PF07561.6 EEQ77189.1 - 0.072 13.1 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1540) Cyclase PF04199.8 EEQ77190.1 - 7.1e-13 48.5 0.0 1.3e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Putative cyclase AA_permease_2 PF13520.1 EEQ77191.1 - 1.9e-58 198.0 52.0 2.3e-58 197.7 36.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ77191.1 - 4.1e-30 104.5 46.8 5.5e-30 104.1 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease UQ_con PF00179.21 EEQ77192.1 - 5.2e-21 74.5 0.0 1e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme HCV_NS5a PF01506.14 EEQ77192.1 - 0.027 14.1 3.4 0.073 12.7 2.3 1.8 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a protein membrane anchor JmjC PF02373.17 EEQ77193.1 - 9.1e-38 129.0 0.7 2.9e-37 127.4 0.5 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 EEQ77193.1 - 1.8e-18 66.5 4.7 3.7e-18 65.5 3.2 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EEQ77193.1 - 8.5e-18 64.3 3.0 2.2e-17 62.9 2.1 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.12 EEQ77193.1 - 9.6e-14 50.6 0.4 2.2e-13 49.4 0.3 1.7 1 0 0 1 1 1 1 jmjN domain PHD PF00628.24 EEQ77193.1 - 7.9 6.2 11.6 19 5.0 3.9 2.5 2 0 0 2 2 2 0 PHD-finger Carn_acyltransf PF00755.15 EEQ77196.1 - 2e-161 538.0 0.0 3.8e-146 487.6 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase AA_permease_2 PF13520.1 EEQ77197.1 - 7.8e-93 311.3 36.4 1e-92 310.9 25.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEQ77197.1 - 3.5e-19 68.5 32.8 7.4e-19 67.4 22.7 1.5 1 1 0 1 1 1 1 Amino acid permease CAP PF00188.21 EEQ77198.1 - 2e-18 67.0 3.6 2.7e-18 66.6 2.5 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Ribosomal_60s PF00428.14 EEQ77198.1 - 0.064 13.6 0.3 0.11 12.8 0.2 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Thioredox_DsbH PF03190.10 EEQ77200.1 - 1.6e-56 190.5 0.0 2.8e-56 189.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 CPSase_L_D3 PF02787.14 EEQ77200.1 - 0.082 12.6 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Glyco_hydro_9 PF00759.14 EEQ77200.1 - 0.16 10.8 0.1 0.25 10.1 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 WD40 PF00400.27 EEQ77201.1 - 6.3e-23 79.7 16.1 2.9e-07 30.1 0.6 6.5 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EEQ77201.1 - 0.0066 14.6 1.1 0.87 7.6 0.2 3.1 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Reg_prop PF07494.6 EEQ77201.1 - 0.044 13.8 0.0 2.1 8.6 0.0 3.0 2 0 0 2 2 2 0 Two component regulator propeller Sigma70_r1_2 PF00140.15 EEQ77201.1 - 0.34 10.6 3.2 0.84 9.3 2.2 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 LSM14 PF12701.2 EEQ77202.1 - 1.8e-30 104.6 0.1 5.7e-29 99.7 0.1 2.4 1 1 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EEQ77202.1 - 8.5e-23 80.8 2.2 2e-22 79.7 1.5 1.6 1 0 0 1 1 1 1 FDF domain ACBP PF00887.14 EEQ77203.1 - 1.4e-25 88.7 0.5 2.7e-25 87.8 0.0 1.7 2 0 0 2 2 2 1 Acyl CoA binding protein Nop14 PF04147.7 EEQ77203.1 - 0.011 13.6 18.2 0.017 13.0 12.6 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EEQ77203.1 - 0.19 9.7 19.3 0.29 9.1 13.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 EEQ77203.1 - 7.4 5.1 30.5 0.66 8.6 16.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) adh_short PF00106.20 EEQ77204.1 - 0.00095 19.1 0.0 0.0022 17.9 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase 4HBT PF03061.17 EEQ77205.1 - 3e-10 40.0 0.0 4.8e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EEQ77205.1 - 0.00038 20.2 0.0 0.00051 19.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily IMS_HHH PF11798.3 EEQ77205.1 - 0.16 12.0 0.4 0.94 9.6 0.1 2.2 2 0 0 2 2 2 0 IMS family HHH motif CHCH PF06747.8 EEQ77206.1 - 6.4e-06 25.9 11.3 0.00011 21.9 3.6 2.4 2 0 0 2 2 2 2 CHCH domain Pet191_N PF10203.4 EEQ77206.1 - 0.028 14.4 11.5 0.25 11.4 5.4 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 EEQ77206.1 - 0.052 13.5 11.4 0.28 11.2 0.8 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 EEQ77206.1 - 0.53 10.0 14.3 1.7 8.4 3.8 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Caprin-1_C PF12287.3 EEQ77207.1 - 0.46 9.7 5.2 0.88 8.8 3.6 1.4 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term Prefoldin PF02996.12 EEQ77208.1 - 2.8e-22 78.6 0.1 5.2e-22 77.7 0.0 1.4 1 1 0 1 1 1 1 Prefoldin subunit tRNA-synt_2b PF00587.20 EEQ77209.1 - 6.1e-32 110.5 0.0 9.9e-32 109.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEQ77209.1 - 1e-11 44.6 0.1 2.5e-11 43.3 0.0 1.7 2 0 0 2 2 2 1 Anticodon binding domain ADK_lid PF05191.9 EEQ77209.1 - 0.02 14.5 1.3 0.2 11.3 0.0 2.4 2 0 0 2 2 2 0 Adenylate kinase, active site lid CBF PF03914.12 EEQ77210.1 - 8.3e-49 165.1 0.7 2.2e-48 163.7 0.5 1.8 1 0 0 1 1 1 1 CBF/Mak21 family LANC_like PF05147.8 EEQ77211.1 - 2e-33 115.4 0.0 2e-32 112.1 0.0 2.1 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein WRW PF10206.4 EEQ77211.1 - 0.17 11.9 0.0 19 5.3 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial F1F0-ATP synthase, subunit f zf-C2H2_jaz PF12171.3 EEQ77213.1 - 3.9e-19 68.2 20.2 4.3e-05 23.5 0.1 4.9 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EEQ77213.1 - 3.5e-14 52.1 19.3 0.0023 18.1 0.7 4.8 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-met PF12874.2 EEQ77213.1 - 7.7e-14 51.3 18.0 0.00033 20.7 0.4 4.8 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EEQ77213.1 - 1e-13 50.5 15.8 0.01 16.0 0.8 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EEQ77213.1 - 2.6e-10 39.8 16.6 0.00011 22.0 0.6 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EEQ77213.1 - 2.7e-07 30.0 15.2 0.15 11.7 0.2 4.3 4 0 0 4 4 4 4 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 EEQ77213.1 - 8.1e-07 29.1 12.5 0.009 16.1 5.6 4.1 1 1 2 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-DNA_Pol PF08996.5 EEQ77213.1 - 2.9e-06 26.7 9.8 0.00029 20.2 1.4 2.4 1 1 2 3 3 3 3 DNA Polymerase alpha zinc finger DUF629 PF04780.7 EEQ77213.1 - 0.00035 19.2 12.8 0.39 9.1 0.2 3.7 1 1 3 4 4 4 3 Protein of unknown function (DUF629) zf-H2C2_2 PF13465.1 EEQ77213.1 - 0.00038 20.5 19.2 0.37 11.1 0.1 5.0 4 1 0 4 4 4 3 Zinc-finger double domain Herpes_UL74 PF07982.7 EEQ77213.1 - 0.0054 15.4 1.7 0.0054 15.4 1.2 1.9 2 1 1 3 3 3 1 Herpes UL74 glycoproteins zf-H2C2_5 PF13909.1 EEQ77213.1 - 0.017 15.3 14.1 0.63 10.3 0.9 4.5 4 0 0 4 4 4 0 C2H2-type zinc-finger domain C1_4 PF07975.7 EEQ77213.1 - 0.067 13.2 13.3 0.49 10.4 2.0 3.5 1 1 2 3 3 3 0 TFIIH C1-like domain Sgf11 PF08209.6 EEQ77213.1 - 0.14 11.4 7.6 17 4.8 0.1 3.7 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zf-LYAR PF08790.6 EEQ77213.1 - 0.34 10.6 8.6 6.8 6.4 0.0 4.2 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger PSP94 PF05825.6 EEQ77213.1 - 0.74 10.1 10.1 4.5 7.6 1.0 3.3 2 1 1 3 3 3 0 Beta-microseminoprotein (PSP-94) DUF2225 PF09986.4 EEQ77213.1 - 1.7 8.0 9.5 11 5.3 6.6 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-AN1 PF01428.11 EEQ77213.1 - 1.8 8.4 11.8 16 5.4 0.5 3.9 4 0 0 4 4 4 0 AN1-like Zinc finger LIM PF00412.17 EEQ77213.1 - 1.9 8.6 9.4 4.6 7.3 1.4 3.4 1 1 1 3 3 3 0 LIM domain Zn_ribbon_2 PF12674.2 EEQ77213.1 - 2.1 8.7 6.4 1.3 9.3 2.2 2.3 2 1 0 2 2 2 0 Putative zinc ribbon domain Rpr2 PF04032.11 EEQ77213.1 - 4.8 7.1 9.1 1.3 8.9 1.4 2.7 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-met2 PF12907.2 EEQ77213.1 - 6.4 6.8 9.6 33 4.5 2.9 3.6 2 1 2 4 4 4 0 Zinc-binding DUF1675 PF07897.6 EEQ77214.1 - 1.8 8.3 22.0 2.8 7.7 15.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Membralin PF09746.4 EEQ77214.1 - 9.8 5.0 10.2 17 4.3 6.5 1.7 2 0 0 2 2 2 0 Tumour-associated protein RNB PF00773.14 EEQ77216.1 - 2.5e-86 289.9 0.1 1.1e-85 287.7 0.0 2.1 2 0 0 2 2 2 1 RNB domain UQ_con PF00179.21 EEQ77217.1 - 2.9e-36 123.9 0.0 6.8e-36 122.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEQ77217.1 - 0.0024 17.6 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B Mucin PF01456.12 EEQ77217.1 - 0.0086 15.8 14.5 0.0086 15.8 10.0 2.1 2 0 0 2 2 2 1 Mucin-like glycoprotein RWD PF05773.17 EEQ77217.1 - 0.0096 15.8 2.1 0.037 13.9 0.0 2.4 2 0 0 2 2 2 1 RWD domain DUF3439 PF11921.3 EEQ77217.1 - 0.1 12.3 14.4 0.24 11.1 10.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FAD_binding_4 PF01565.18 EEQ77220.1 - 3e-16 59.1 0.1 7.5e-16 57.8 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEQ77220.1 - 1.6e-05 24.7 0.1 3.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like TPR_20 PF14561.1 EEQ77221.1 - 0.063 13.3 0.4 0.12 12.5 0.3 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat NAD_binding_3 PF03447.11 EEQ77221.1 - 0.069 13.5 0.2 0.089 13.1 0.1 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain MMR_HSR1 PF01926.18 EEQ77222.1 - 2.4e-17 62.9 0.0 3.5e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EEQ77222.1 - 1.1e-07 31.8 0.1 0.00062 19.6 0.0 2.5 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.11 EEQ77222.1 - 6.7e-06 25.3 0.0 9.9e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.5 EEQ77222.1 - 0.001 18.3 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 EEQ77222.1 - 0.0023 17.4 0.0 0.0048 16.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FeoB_N PF02421.13 EEQ77222.1 - 0.0088 15.3 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EEQ77222.1 - 0.0095 15.1 0.4 0.023 13.9 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GBP PF02263.14 EEQ77222.1 - 0.02 13.9 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Gtr1_RagA PF04670.7 EEQ77222.1 - 0.024 13.7 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 EEQ77222.1 - 0.035 14.4 0.1 0.059 13.6 0.1 1.5 1 1 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.22 EEQ77222.1 - 0.035 13.5 0.0 1.1 8.7 0.0 2.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Septin PF00735.13 EEQ77222.1 - 0.046 12.7 0.1 0.12 11.3 0.0 1.6 1 1 0 1 1 1 0 Septin AAA_10 PF12846.2 EEQ77222.1 - 0.2 11.0 1.1 0.23 10.8 0.7 1.3 1 1 0 1 1 1 0 AAA-like domain WD40 PF00400.27 EEQ77223.1 - 6e-56 184.4 15.7 6.6e-09 35.3 0.2 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EEQ77223.1 - 5.1e-08 32.5 0.1 1.1e-07 31.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ77223.1 - 5.4e-08 32.3 0.3 1.2e-07 31.2 0.2 1.5 1 0 0 1 1 1 1 F-box domain HORMA PF02301.13 EEQ77224.1 - 3.1e-50 170.5 0.0 6e-50 169.6 0.0 1.5 1 0 0 1 1 1 1 HORMA domain PHD PF00628.24 EEQ77224.1 - 3.6e-05 23.3 7.2 7.5e-05 22.3 5.0 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EEQ77224.1 - 0.14 11.4 3.1 0.38 10.0 2.2 1.7 1 1 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 EEQ77224.1 - 0.17 11.6 2.5 0.39 10.4 1.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Histone PF00125.19 EEQ77226.1 - 0.12 12.5 0.1 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TACI-CRD2 PF09305.5 EEQ77226.1 - 1.3 8.9 5.1 0.75 9.6 1.0 2.2 1 1 1 2 2 2 0 TACI, cysteine-rich domain Nuc_sug_transp PF04142.10 EEQ77228.1 - 1.2e-66 224.2 0.3 1.8e-66 223.7 0.2 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EEQ77228.1 - 0.00012 22.0 6.1 0.00012 22.0 4.2 2.6 2 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 EEQ77228.1 - 0.00017 21.7 15.3 0.00019 21.5 1.8 2.7 2 0 0 2 2 2 2 Multidrug resistance efflux transporter TPT PF03151.11 EEQ77228.1 - 0.0081 15.8 16.6 0.013 15.1 2.0 3.2 3 0 0 3 3 3 2 Triose-phosphate Transporter family UAA PF08449.6 EEQ77228.1 - 2.4 7.0 8.3 3.2 6.5 0.5 3.0 2 1 1 3 3 3 0 UAA transporter family Sec63 PF02889.11 EEQ77229.1 - 8.4e-48 163.1 0.1 1.5e-47 162.3 0.0 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EEQ77229.1 - 1.4e-28 99.5 0.0 2.6e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEQ77229.1 - 1.6e-08 34.2 0.0 4.4e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ77229.1 - 1.7e-08 34.4 0.1 5.2e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EEQ77229.1 - 0.00046 20.3 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain SNF2_N PF00176.18 EEQ77229.1 - 0.0017 17.2 0.3 0.0079 15.0 0.1 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_RecD PF05127.9 EEQ77229.1 - 0.031 13.9 0.0 0.066 12.8 0.0 1.6 1 0 0 1 1 1 0 Helicase AAA_19 PF13245.1 EEQ77229.1 - 0.045 13.5 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain HHH_5 PF14520.1 EEQ77229.1 - 0.1 12.8 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Acid_PPase PF12689.2 EEQ77230.1 - 9.7e-69 230.3 0.0 1.1e-68 230.1 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 EEQ77230.1 - 0.001 19.3 0.9 0.036 14.2 0.0 2.8 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Hexapep PF00132.19 EEQ77231.1 - 1e-06 27.9 16.1 0.0043 16.5 3.3 4.8 3 2 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EEQ77231.1 - 0.29 10.7 11.5 0.21 11.1 1.3 3.9 4 1 1 5 5 5 0 Hexapeptide repeat of succinyl-transferase TPR_MLP1_2 PF07926.7 EEQ77232.1 - 3.2e-33 114.2 29.7 3.2e-33 114.2 20.6 16.0 6 4 4 12 12 12 4 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 EEQ77232.1 - 2.1e-05 24.4 30.1 0.0003 20.6 3.6 16.0 5 5 8 15 15 15 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.6 EEQ77232.1 - 0.00043 18.8 5.4 0.00043 18.8 3.8 9.6 4 4 5 9 9 9 1 Weak chloroplast movement under blue light Tropomyosin_1 PF12718.2 EEQ77232.1 - 0.0036 17.1 14.9 0.0036 17.1 10.4 14.5 5 5 7 14 14 14 4 Tropomyosin like MtrG PF04210.8 EEQ77232.1 - 0.84 9.3 9.1 10 5.9 0.1 5.4 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G TFIIE_beta PF02186.10 EEQ77233.1 - 2.4e-07 30.6 0.0 6.5e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 TFIIE beta subunit core domain DUF3446 PF11928.3 EEQ77233.1 - 0.74 10.0 5.0 1.6 8.9 3.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) DHBP_synthase PF00926.14 EEQ77234.1 - 6.1e-71 237.6 0.0 1.8e-70 236.1 0.0 1.6 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase F-box-like PF12937.2 EEQ77235.1 - 0.0021 17.7 0.7 0.0045 16.6 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ77235.1 - 0.024 14.2 0.1 0.098 12.3 0.1 2.0 2 0 0 2 2 2 0 F-box domain Pkinase PF00069.20 EEQ77236.1 - 1.2e-59 201.5 0.0 2.2e-59 200.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ77236.1 - 1.3e-26 93.2 0.0 2e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ77236.1 - 9.8e-10 37.8 0.0 1.5e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEQ77236.1 - 0.0087 15.1 0.0 0.017 14.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ77236.1 - 0.053 13.2 0.0 0.38 10.4 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family UQ_con PF00179.21 EEQ77237.1 - 2.1e-47 160.0 0.0 2.5e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEQ77237.1 - 4.5e-05 23.2 0.0 6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EEQ77237.1 - 0.00093 18.8 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 EEQ77237.1 - 0.0013 18.5 0.0 0.0019 18.0 0.0 1.5 1 1 0 1 1 1 1 RWD domain Nucleos_tra2_C PF07662.8 EEQ77238.1 - 2.9e-67 226.2 1.5 2.9e-67 226.2 1.0 2.7 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EEQ77238.1 - 2e-23 82.4 6.2 2e-23 82.4 4.3 2.9 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 EEQ77238.1 - 0.0003 20.6 17.3 0.00045 20.1 5.7 3.5 2 1 0 2 2 2 2 Nucleoside recognition SNF2_N PF00176.18 EEQ77240.1 - 1.9e-68 230.4 0.2 2.9e-68 229.8 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ77240.1 - 6.1e-12 45.2 0.0 1.6e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EEQ77240.1 - 6.1e-09 35.4 3.0 1.3e-08 34.3 2.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ77240.1 - 1.3e-07 31.5 6.0 2.8e-07 30.4 4.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 EEQ77240.1 - 9.9e-07 28.3 0.0 3.1e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 EEQ77240.1 - 2.7e-05 23.7 4.6 6.1e-05 22.6 3.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EEQ77240.1 - 2.7e-05 23.7 4.9 7e-05 22.4 3.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ77240.1 - 8.3e-05 22.3 4.8 0.00018 21.2 3.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.1 EEQ77240.1 - 0.0037 16.8 2.6 0.014 14.9 1.8 1.9 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EEQ77240.1 - 0.028 14.3 5.2 0.095 12.5 3.7 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Mu-like_Com PF10122.4 EEQ77240.1 - 0.034 13.2 0.2 0.092 11.8 0.2 1.7 1 0 0 1 1 1 0 Mu-like prophage protein Com zf-RING_UBOX PF13445.1 EEQ77240.1 - 0.034 13.8 1.4 0.095 12.4 1.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger SCP2 PF02036.12 EEQ77243.1 - 2e-24 85.8 0.2 2.6e-24 85.4 0.1 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EEQ77243.1 - 5.2e-08 32.9 0.0 6.4e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Ran_BP1 PF00638.13 EEQ77245.1 - 9.5e-13 48.2 0.0 1.7e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.1 EEQ77245.1 - 0.0032 17.6 37.5 0.0032 17.6 26.0 11.2 4 3 7 11 11 11 4 Nucleoporin FG repeat region DUF4632 PF15451.1 EEQ77245.1 - 0.11 12.4 1.6 0.39 10.6 1.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Ribosomal_L31e PF01198.14 EEQ77246.1 - 6.3e-38 128.3 1.3 7.9e-38 128.0 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e MS_channel PF00924.13 EEQ77246.1 - 0.12 11.6 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel CN_hydrolase PF00795.17 EEQ77247.1 - 5.6e-33 113.8 0.0 7.3e-33 113.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Aminotran_3 PF00202.16 EEQ77248.1 - 5.6e-10 38.5 0.0 8e-10 38.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EEQ77248.1 - 0.00023 20.2 0.0 0.00033 19.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.14 EEQ77248.1 - 0.22 9.9 0.0 0.53 8.6 0.0 1.5 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain PNP_UDP_1 PF01048.15 EEQ77249.1 - 3.4e-09 36.0 0.1 1.2e-08 34.1 0.1 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily DUF605 PF04652.11 EEQ77249.1 - 0.33 10.2 9.8 0.46 9.8 6.8 1.2 1 0 0 1 1 1 0 Vta1 like Tyrosinase PF00264.15 EEQ77250.1 - 9.6e-56 189.4 1.4 1.6e-55 188.7 1.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase ALF PF03752.8 EEQ77250.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Short repeats of unknown function Ank PF00023.25 EEQ77251.1 - 3.3e-15 55.0 3.3 2.7e-09 36.3 0.3 4.1 5 0 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.2 EEQ77251.1 - 5e-14 52.4 2.1 2.1e-13 50.4 0.4 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEQ77251.1 - 2.4e-12 47.0 0.6 1.5e-07 31.7 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ77251.1 - 7.9e-11 41.1 0.1 5.6e-06 26.0 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EEQ77251.1 - 4.7e-09 36.1 0.3 4.7e-07 29.8 0.1 3.0 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 EEQ77252.1 - 8.7e-20 69.4 0.5 1.3e-06 27.8 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 EEQ77252.1 - 1.8e-17 63.4 0.0 6.3e-08 32.8 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEQ77252.1 - 5.5e-16 58.2 0.2 3.6e-07 30.1 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ77252.1 - 2.5e-14 51.9 0.0 0.00043 20.2 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EEQ77252.1 - 3.9e-13 49.5 0.0 0.0016 18.9 0.0 4.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) vWA-TerF-like PF10138.4 EEQ77252.1 - 0.036 13.8 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 vWA found in TerF C terminus DUF3298 PF11738.3 EEQ77252.1 - 0.11 13.0 0.0 0.42 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3298) SBP_bac_8 PF13416.1 EEQ77252.1 - 0.11 12.2 0.8 0.18 11.5 0.2 1.7 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein ADH_zinc_N PF00107.21 EEQ77253.1 - 5.8e-16 58.2 0.9 1.1e-15 57.3 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEQ77253.1 - 3.6e-11 42.7 0.0 1.2e-10 41.0 0.0 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EEQ77253.1 - 0.052 13.5 0.6 0.078 12.9 0.4 1.3 1 0 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 EEQ77253.1 - 0.088 12.7 0.6 0.16 11.8 0.4 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Prominin PF05478.6 EEQ77255.1 - 0.54 7.7 0.0 0.83 7.1 0.0 1.1 1 0 0 1 1 1 0 Prominin ATG2_CAD PF13329.1 EEQ77256.1 - 1.7e-50 170.6 0.4 4.4e-50 169.3 0.3 1.8 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 EEQ77256.1 - 2.4e-27 94.9 0.0 8e-27 93.2 0.0 2.0 1 0 0 1 1 1 1 ATG C terminal domain AMP-binding PF00501.23 EEQ77257.1 - 1.8e-18 66.1 0.5 9.6e-09 34.1 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ77257.1 - 2.5e-11 44.3 0.1 6e-11 43.1 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Lyase_1 PF00206.15 EEQ77258.1 - 2e-23 83.1 0.0 3.6e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EEQ77258.1 - 1.1e-13 50.9 0.0 4.4e-13 49.0 0.0 2.1 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus DUF2408 PF10303.4 EEQ77258.1 - 0.065 13.3 0.0 0.36 10.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) APH PF01636.18 EEQ77261.1 - 1.2e-12 48.1 0.0 5.8e-12 45.8 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EEQ77261.1 - 0.029 13.3 0.0 0.33 9.8 0.0 2.0 2 0 0 2 2 2 0 Fructosamine kinase CENP-B_dimeris PF09026.5 EEQ77262.1 - 0.042 14.0 0.9 0.058 13.6 0.7 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CobT_C PF11775.3 EEQ77266.1 - 0.00012 21.5 0.0 0.00021 20.8 0.0 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT VWA domain Sina PF03145.11 EEQ77266.1 - 0.047 13.3 1.0 0.097 12.3 0.7 1.5 1 0 0 1 1 1 0 Seven in absentia protein family Spindle_Spc25 PF08234.7 EEQ77266.1 - 0.37 10.8 4.1 0.63 10.0 0.0 2.9 3 0 0 3 3 3 0 Chromosome segregation protein Spc25 ATP_bind_3 PF01171.15 EEQ77269.1 - 8.5e-19 67.7 0.0 1.5e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 EEQ77269.1 - 0.00068 19.9 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) zf-UBR PF02207.15 EEQ77269.1 - 0.095 12.4 4.5 1.3 8.8 0.2 2.5 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) tRNA_Me_trans PF03054.11 EEQ77269.1 - 0.1 11.1 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase RecR PF02132.10 EEQ77269.1 - 0.22 10.9 4.5 0.089 12.2 0.3 2.4 2 0 0 2 2 2 0 RecR protein Acetyltransf_8 PF13523.1 EEQ77270.1 - 1e-36 126.1 0.0 1.5e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEQ77270.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EEQ77270.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AA_kinase PF00696.23 EEQ77272.1 - 6.7e-41 140.4 1.2 9.8e-41 139.8 0.9 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EEQ77272.1 - 1.8e-17 62.8 0.9 9.1e-17 60.5 0.1 2.3 2 0 0 2 2 2 1 PUA domain Peptidase_M76 PF09768.4 EEQ77273.1 - 8.8e-70 233.6 4.8 1.1e-69 233.3 3.3 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 EEQ77273.1 - 0.21 11.2 5.3 0.2 11.3 2.7 1.9 1 1 1 2 2 2 0 SprT-like family Pkinase PF00069.20 EEQ77274.1 - 1.5e-70 237.3 0.0 2e-70 236.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ77274.1 - 3.5e-43 147.5 0.0 4.6e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ77274.1 - 6.4e-07 28.6 0.0 4.9e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EEQ77274.1 - 9.5e-05 21.5 0.1 0.00016 20.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EEQ77274.1 - 0.008 15.5 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 EEQ77274.1 - 0.072 12.8 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family TIP41 PF04176.8 EEQ77275.1 - 8.7e-80 266.2 0.0 1.1e-79 265.9 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family Tom22 PF04281.8 EEQ77276.1 - 1.4e-49 167.1 0.1 1.7e-49 166.9 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 YL1 PF05764.8 EEQ77276.1 - 0.21 11.1 1.4 0.23 11.0 1.0 1.1 1 0 0 1 1 1 0 YL1 nuclear protein AMP-binding PF00501.23 EEQ77277.1 - 1.1e-35 122.9 0.0 2e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ77277.1 - 0.04 14.8 0.1 0.65 10.9 0.0 2.7 3 1 1 4 4 4 0 AMP-binding enzyme C-terminal domain RHIM PF12721.2 EEQ77277.1 - 0.79 10.1 10.2 2.1 8.8 7.1 1.7 1 0 0 1 1 1 0 RIP homotypic interaction motif DUF3439 PF11921.3 EEQ77277.1 - 6.7 6.4 15.1 15 5.3 10.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) MSP1_C PF07462.6 EEQ77277.1 - 7.2 4.8 6.6 11 4.2 4.6 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Peptidase_M16_C PF05193.16 EEQ77278.1 - 4e-39 134.1 0.0 3.4e-38 131.1 0.0 2.2 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EEQ77278.1 - 7.3e-19 67.9 0.0 1.5e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Abhydrolase_2 PF02230.11 EEQ77279.1 - 8.2e-28 97.3 0.0 3.4e-18 65.8 0.0 3.0 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EEQ77279.1 - 4.7e-11 42.9 2.0 9.1e-11 42.0 1.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ77279.1 - 2e-07 30.8 0.0 1e-06 28.6 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EEQ77279.1 - 0.00074 19.1 0.9 0.0019 17.7 0.6 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEQ77279.1 - 0.0022 17.2 1.6 0.0077 15.4 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.8 EEQ77279.1 - 0.069 12.5 0.0 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Aminotran_1_2 PF00155.16 EEQ77280.1 - 7.4e-22 77.7 0.0 1e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Tmemb_18A PF09771.4 EEQ77280.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 188 PQ-loop PF04193.9 EEQ77282.1 - 4.3e-38 128.6 14.1 9.5e-19 66.7 0.9 2.7 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 EEQ77282.1 - 0.26 11.1 8.1 0.69 9.8 0.0 2.5 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange ADH_N PF08240.7 EEQ77284.1 - 6.8e-30 103.0 1.7 1.1e-29 102.3 1.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ77284.1 - 3.1e-17 62.3 0.0 4.3e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EEQ77284.1 - 0.065 12.3 0.1 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 EEQ77284.1 - 0.12 13.2 0.0 0.19 12.5 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Guanylate_kin PF00625.16 EEQ77287.1 - 1.6e-65 220.0 0.0 1.9e-65 219.7 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 EEQ77287.1 - 5e-09 36.4 0.0 8.2e-09 35.7 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EEQ77287.1 - 8.5e-08 32.1 0.0 3.9e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEQ77287.1 - 3.2e-06 27.3 0.0 5.6e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEQ77287.1 - 2e-05 24.8 0.1 0.00025 21.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEQ77287.1 - 3e-05 24.8 0.5 0.00031 21.5 0.3 2.3 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EEQ77287.1 - 3.3e-05 23.8 0.0 6.5e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EEQ77287.1 - 0.00026 20.2 0.0 0.00047 19.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 EEQ77287.1 - 0.00043 20.2 0.3 0.0013 18.7 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEQ77287.1 - 0.00051 19.7 0.1 0.0016 18.1 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain ABC_tran PF00005.22 EEQ77287.1 - 0.0007 19.9 0.0 0.00092 19.5 0.0 1.6 1 1 0 1 1 1 1 ABC transporter Miro PF08477.8 EEQ77287.1 - 0.00093 19.6 0.0 0.002 18.6 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein AAA PF00004.24 EEQ77287.1 - 0.0013 18.9 0.0 0.0072 16.5 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EEQ77287.1 - 0.0014 18.5 0.0 0.0028 17.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EEQ77287.1 - 0.0014 18.3 0.1 0.01 15.5 0.1 2.0 1 1 0 1 1 1 1 Archaeal ATPase AAA_29 PF13555.1 EEQ77287.1 - 0.0031 16.9 0.0 0.0093 15.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 EEQ77287.1 - 0.0037 17.4 0.0 0.007 16.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Rad17 PF03215.10 EEQ77287.1 - 0.006 15.3 0.0 0.0068 15.1 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 EEQ77287.1 - 0.0091 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EEQ77287.1 - 0.011 16.1 0.1 0.12 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF1895 PF08988.5 EEQ77287.1 - 0.012 15.6 0.2 0.022 14.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1895) NACHT PF05729.7 EEQ77287.1 - 0.018 14.6 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 EEQ77287.1 - 0.019 13.9 0.0 0.81 8.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 EEQ77287.1 - 0.021 13.7 0.0 0.067 12.0 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 EEQ77287.1 - 0.022 14.2 0.2 0.024 14.1 0.1 1.6 1 1 0 1 1 1 0 AAA-like domain AAA_5 PF07728.9 EEQ77287.1 - 0.024 14.3 0.0 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.14 EEQ77287.1 - 0.027 13.9 0.0 0.43 10.0 0.0 2.2 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EEQ77287.1 - 0.033 13.8 0.4 0.074 12.7 0.1 1.9 1 1 1 2 2 2 0 NTPase Viral_helicase1 PF01443.13 EEQ77287.1 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EEQ77287.1 - 0.052 13.1 0.1 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EEQ77287.1 - 0.053 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AP_endonuc_2 PF01261.19 EEQ77287.1 - 0.099 11.9 0.0 0.19 10.9 0.0 1.5 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel RNA12 PF10443.4 EEQ77287.1 - 0.11 10.9 0.0 1.1 7.6 0.0 1.9 2 0 0 2 2 2 0 RNA12 protein AAA_25 PF13481.1 EEQ77287.1 - 0.12 11.7 0.0 0.6 9.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 EEQ77287.1 - 0.13 11.2 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 Septin GRAB PF10375.4 EEQ77288.1 - 5.8e-09 35.2 0.2 1.4e-08 34.0 0.1 1.7 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Reo_sigmaC PF04582.7 EEQ77288.1 - 0.0015 17.7 10.7 0.063 12.4 2.5 2.2 2 0 0 2 2 2 2 Reovirus sigma C capsid protein Mqo PF06039.10 EEQ77288.1 - 0.019 13.1 3.8 0.58 8.2 0.2 2.3 1 1 1 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FliJ PF02050.11 EEQ77288.1 - 0.74 9.8 45.9 1.1 9.3 3.3 3.9 1 1 2 3 3 3 0 Flagellar FliJ protein Mt_ATP-synt_D PF05873.7 EEQ77288.1 - 0.74 9.4 10.7 0.088 12.4 3.7 2.1 1 1 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Baculo_PEP_C PF04513.7 EEQ77288.1 - 1.5 8.6 16.9 1.2 8.9 2.8 3.1 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin PF00261.15 EEQ77288.1 - 3.1 6.8 55.5 0.56 9.2 13.1 2.9 1 1 1 2 2 2 0 Tropomyosin Filament PF00038.16 EEQ77288.1 - 4 6.8 48.4 2.7 7.3 15.4 2.5 1 1 1 2 2 2 0 Intermediate filament protein DUF3367 PF11847.3 EEQ77288.1 - 7.1 4.4 4.9 12 3.7 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) TBCC PF07986.7 EEQ77289.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor C DUF2183 PF09949.4 EEQ77290.1 - 7.2e-16 57.9 0.1 1.5e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DAO PF01266.19 EEQ77296.1 - 1.6e-48 165.4 0.0 2.2e-48 164.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEQ77296.1 - 1.2e-08 34.2 0.6 4.1e-08 32.4 0.4 1.8 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EEQ77296.1 - 3.6e-07 29.6 0.2 4.8e-06 25.9 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEQ77296.1 - 0.00047 20.0 0.1 0.0013 18.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EEQ77296.1 - 0.0016 18.1 0.1 0.0029 17.2 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EEQ77296.1 - 0.0019 17.1 0.1 0.018 13.9 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EEQ77296.1 - 0.0074 16.2 0.2 0.02 14.9 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EEQ77296.1 - 0.013 15.9 0.1 0.041 14.2 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEQ77296.1 - 0.02 13.4 0.3 0.034 12.6 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_10 PF13460.1 EEQ77296.1 - 0.058 13.4 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 NADH(P)-binding Lycopene_cycl PF05834.7 EEQ77296.1 - 0.061 12.2 0.1 0.096 11.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 EEQ77296.1 - 0.2 10.6 0.2 1.6 7.7 0.0 2.1 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 EEQ77297.1 - 5.7e-16 58.5 2.0 8.9e-15 54.5 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain SE PF08491.5 EEQ77297.1 - 0.0023 16.7 0.0 0.0039 16.0 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.1 EEQ77297.1 - 0.0081 15.9 0.5 0.099 12.4 0.1 2.2 1 1 1 2 2 2 1 FAD-NAD(P)-binding Semialdhyde_dh PF01118.19 EEQ77297.1 - 0.13 12.6 0.0 0.71 10.1 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Ecl1 PF12855.2 EEQ77300.1 - 1.7e-07 30.4 0.6 3.4e-07 29.4 0.4 1.6 1 0 0 1 1 1 1 Life-span regulatory factor AflR PF08493.5 EEQ77300.1 - 3.6 6.5 14.7 4.8 6.1 10.2 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein Ashwin PF15323.1 EEQ77300.1 - 9 6.2 12.9 11 5.9 8.9 1.3 1 1 0 1 1 1 0 Developmental protein DASH_Dad2 PF08654.5 EEQ77302.1 - 1.3e-37 127.8 0.5 1.7e-37 127.5 0.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 Shugoshin_N PF07558.6 EEQ77303.1 - 4.8e-17 61.3 5.1 1.4e-16 59.8 3.5 1.9 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 EEQ77303.1 - 2.1e-10 39.8 6.1 2.1e-10 39.8 4.2 4.2 5 0 0 5 5 5 1 Shugoshin C terminus Mod_r PF07200.8 EEQ77303.1 - 0.0035 17.2 0.8 0.0098 15.8 0.6 1.8 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein HALZ PF02183.13 EEQ77303.1 - 0.68 9.7 2.8 0.79 9.4 0.8 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper PPI_Ypi1 PF07491.6 EEQ77304.1 - 1.7e-23 82.0 5.4 9.2e-23 79.6 3.8 2.3 1 1 0 1 1 1 1 Protein phosphatase inhibitor Ubiq_cyt_C_chap PF03981.7 EEQ77305.1 - 7.7e-39 132.7 0.0 1e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Peptidase_M1 PF01433.15 EEQ77306.1 - 1.9e-62 211.5 0.0 2.7e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EEQ77306.1 - 1.9e-40 137.7 0.0 3.1e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EEQ77306.1 - 3e-17 62.8 0.0 5.2e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EEQ77306.1 - 0.11 12.5 2.8 0.42 10.5 1.9 1.9 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Peptidase_C2 PF00648.16 EEQ77307.1 - 3e-14 52.7 0.0 4.5e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EEQ77307.1 - 2.1e-11 43.6 0.0 0.00018 21.1 0.0 2.5 1 1 1 2 2 2 2 Calpain large subunit, domain III GAGA_bind PF06217.7 EEQ77308.1 - 0.65 9.9 5.7 0.75 9.6 4.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4064 PF13273.1 EEQ77309.1 - 0.0019 18.2 1.4 0.0023 17.9 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) MIG-14_Wnt-bd PF06664.7 EEQ77309.1 - 0.0052 15.6 0.7 0.006 15.4 0.5 1.0 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Bac_rhodopsin PF01036.13 EEQ77309.1 - 0.012 14.8 0.4 0.015 14.6 0.3 1.1 1 0 0 1 1 1 0 Bacteriorhodopsin-like protein MARVEL PF01284.18 EEQ77309.1 - 0.039 13.7 4.1 0.047 13.5 2.8 1.2 1 0 0 1 1 1 0 Membrane-associating domain ATP-synt_A PF00119.15 EEQ77309.1 - 0.05 13.0 0.8 0.063 12.7 0.6 1.1 1 0 0 1 1 1 0 ATP synthase A chain ABC_membrane PF00664.18 EEQ77309.1 - 0.05 13.0 1.8 0.06 12.7 1.2 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF4013 PF13197.1 EEQ77309.1 - 0.067 12.5 2.8 0.082 12.2 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) Yip1 PF04893.12 EEQ77309.1 - 0.093 12.2 2.6 0.11 12.0 1.8 1.1 1 0 0 1 1 1 0 Yip1 domain DUF3810 PF12725.2 EEQ77309.1 - 0.099 11.5 1.2 0.12 11.2 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Tetraspannin PF00335.15 EEQ77309.1 - 0.13 11.5 1.9 0.15 11.2 1.3 1.1 1 0 0 1 1 1 0 Tetraspanin family YlaH PF14036.1 EEQ77309.1 - 0.14 12.2 2.1 0.5 10.4 0.1 2.0 2 0 0 2 2 2 0 YlaH-like protein DUF3753 PF12575.3 EEQ77309.1 - 0.2 11.4 2.7 0.71 9.7 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) AgrB PF04647.10 EEQ77309.1 - 0.35 9.9 4.8 0.55 9.2 3.2 1.4 1 1 0 1 1 1 0 Accessory gene regulator B DUF3382 PF11862.3 EEQ77309.1 - 0.62 10.0 3.8 8.5 6.3 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3382) RCR PF12273.3 EEQ77309.1 - 0.84 10.1 2.7 18 5.9 0.0 2.1 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Radical_SAM PF04055.16 EEQ77310.1 - 4.4e-17 62.7 0.1 1.4e-16 61.1 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EEQ77310.1 - 3.4e-12 46.2 0.0 8.8e-12 44.8 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EEQ77310.1 - 0.099 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CoA_binding PF02629.14 EEQ77311.1 - 2e-26 92.3 6.7 2.7e-26 91.9 0.7 2.6 2 1 1 3 3 3 1 CoA binding domain Ligase_CoA PF00549.14 EEQ77311.1 - 5.1e-22 78.1 0.3 8.5e-22 77.3 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EEQ77311.1 - 5.3e-06 26.0 0.0 9.3e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EEQ77311.1 - 0.0001 22.4 0.1 0.00024 21.2 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain Ank PF00023.25 EEQ77312.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeat Ank_5 PF13857.1 EEQ77312.1 - 0.014 15.6 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) SNF2_N PF00176.18 EEQ77315.1 - 1.7e-83 279.8 0.5 1.7e-83 279.8 0.4 3.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EEQ77315.1 - 2.1e-25 88.4 0.6 8e-24 83.3 0.1 2.7 2 0 0 2 2 2 1 Bromodomain SnAC PF14619.1 EEQ77315.1 - 2.9e-17 62.6 3.1 2.9e-17 62.6 2.1 4.1 5 0 0 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex Helicase_C PF00271.26 EEQ77315.1 - 5.5e-17 61.3 0.0 5.5e-17 61.3 0.0 3.3 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.8 EEQ77315.1 - 4.9e-12 45.4 11.7 4.9e-12 45.4 8.1 3.2 3 0 0 3 3 3 1 HSA Zip PF02535.17 EEQ77315.1 - 1 8.2 1.5 2.9 6.8 1.1 1.8 1 0 0 1 1 1 0 ZIP Zinc transporter BAR PF03114.13 EEQ77317.1 - 1.8e-49 168.3 8.4 2.2e-49 168.0 5.8 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 EEQ77317.1 - 0.12 11.7 7.4 0.32 10.3 5.1 1.9 1 1 0 1 1 1 0 Arfaptin-like domain ADH_N PF08240.7 EEQ77319.1 - 2.3e-05 24.1 0.0 5.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ77319.1 - 0.024 14.1 0.6 0.051 13.1 0.4 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EEQ77320.1 - 2.5e-19 69.5 0.0 4.1e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ77320.1 - 5.9e-08 33.2 0.0 1e-06 29.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ77320.1 - 8e-06 26.2 0.0 1.7e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ77320.1 - 2.6e-05 23.8 0.0 0.00042 19.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ77320.1 - 0.00017 22.0 0.0 0.0017 18.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ77320.1 - 0.0045 17.3 0.0 0.014 15.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EEQ77320.1 - 0.017 15.1 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase AftA_N PF12250.3 EEQ77321.1 - 0.1 11.3 0.1 0.21 10.2 0.0 1.5 2 0 0 2 2 2 0 Arabinofuranosyltransferase N terminal Aa_trans PF01490.13 EEQ77322.1 - 1.2e-42 145.8 36.5 1.5e-42 145.5 25.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ada_Zn_binding PF02805.11 EEQ77323.1 - 1.3e-29 101.5 5.2 3.3e-29 100.2 3.6 1.7 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 EEQ77323.1 - 4.9e-08 32.5 0.0 1.1e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 EEQ77323.1 - 0.00018 21.5 0.0 0.00038 20.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Sensor PF13796.1 EEQ77324.1 - 4 6.9 10.6 0.29 10.7 2.1 2.3 2 0 0 2 2 2 0 Putative sensor Ribosomal_L2_C PF03947.13 EEQ77325.1 - 2.9e-37 127.3 4.0 5e-37 126.6 2.8 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EEQ77325.1 - 1.3e-11 44.3 0.1 2.6e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain WHIM1 PF15612.1 EEQ77326.1 - 0.023 14.6 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 DUF1770 PF08589.5 EEQ77327.1 - 4e-24 85.1 2.2 4.9e-24 84.8 1.5 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) PfkB PF00294.19 EEQ77328.1 - 1.2e-65 221.6 0.0 1.4e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EEQ77328.1 - 0.0035 16.5 0.0 0.0063 15.7 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.4 EEQ77329.1 - 2.1e-63 214.1 0.9 3.5e-63 213.4 0.2 1.7 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EEQ77329.1 - 7.4e-24 84.2 0.1 3.1e-23 82.2 0.1 2.0 2 0 0 2 2 2 1 Telomerase activating protein Est1 TPR_11 PF13414.1 EEQ77329.1 - 0.00034 20.1 0.6 0.00074 19.1 0.4 1.5 1 0 0 1 1 1 1 TPR repeat Acyl-CoA_dh_1 PF00441.19 EEQ77330.1 - 1e-28 100.3 1.5 1.8e-28 99.5 1.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EEQ77330.1 - 5.9e-15 54.5 0.0 1.3e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EEQ77330.1 - 6.8e-14 52.2 1.4 1.2e-13 51.4 1.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EEQ77330.1 - 9.3e-14 51.9 0.3 2.4e-13 50.6 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Histone PF00125.19 EEQ77331.1 - 0.041 14.0 0.5 0.056 13.5 0.3 1.2 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Spo12 PF05032.7 EEQ77332.1 - 4.9e-16 58.0 0.6 4.9e-16 58.0 0.4 1.8 2 0 0 2 2 2 1 Spo12 family Sad1_UNC PF07738.8 EEQ77334.1 - 1.3e-34 118.8 0.0 2.7e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF3619 PF12279.3 EEQ77335.1 - 0.014 15.4 0.1 0.025 14.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Pkinase PF00069.20 EEQ77336.1 - 5.1e-59 199.5 0.0 1.3e-58 198.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ77336.1 - 1.2e-34 119.6 0.0 1.8e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ77336.1 - 4.8e-12 45.4 0.0 4.1e-10 39.1 0.0 2.5 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.9 EEQ77336.1 - 0.003 16.6 0.0 0.0052 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ77336.1 - 0.064 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EEQ77336.1 - 0.2 10.3 0.0 0.35 9.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Hex_IIIa PF02455.11 EEQ77336.1 - 1.3 7.5 7.4 2.1 6.9 5.1 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Pep3_Vps18 PF05131.9 EEQ77338.1 - 4.3e-47 159.2 0.0 1e-46 157.9 0.0 1.7 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EEQ77338.1 - 4.3e-07 29.6 7.5 0.00039 20.0 0.1 3.4 4 0 0 4 4 4 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EEQ77338.1 - 0.00015 21.5 0.3 0.00039 20.1 0.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EEQ77338.1 - 0.00072 19.2 0.3 0.0019 17.9 0.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Vps39_2 PF10367.4 EEQ77338.1 - 0.016 15.3 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 PspA_IM30 PF04012.7 EEQ77338.1 - 0.038 13.3 0.7 0.096 12.0 0.0 1.9 2 0 0 2 2 2 0 PspA/IM30 family DUF2175 PF09943.4 EEQ77338.1 - 0.096 12.7 0.1 0.34 10.9 0.1 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) zf-rbx1 PF12678.2 EEQ77338.1 - 0.12 12.4 0.2 0.67 10.0 0.1 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EEQ77338.1 - 0.15 12.0 0.9 0.4 10.7 0.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UCH_1 PF13423.1 EEQ77339.1 - 2.1e-92 309.7 0.0 3.4e-92 309.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L5_C PF00673.16 EEQ77340.1 - 1.4e-25 88.8 0.0 2.4e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Msg2_C PF12373.3 EEQ77340.1 - 0.074 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Major surface glycoprotein 2 C terminal Pkinase PF00069.20 EEQ77341.1 - 6.5e-66 222.1 0.0 1.3e-65 221.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ77341.1 - 1.1e-47 162.3 0.0 2.5e-47 161.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EEQ77341.1 - 1.5e-31 108.3 0.0 2.8e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 EEQ77341.1 - 2e-15 56.7 0.2 4.2e-15 55.6 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EEQ77341.1 - 6.1e-13 48.4 0.1 1.3e-12 47.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 EEQ77341.1 - 8.2e-08 31.5 0.0 0.00047 19.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like RA PF00788.18 EEQ77341.1 - 0.00023 21.5 0.0 0.00044 20.6 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain DUF1221 PF06760.6 EEQ77341.1 - 0.0011 18.2 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1221) Kdo PF06293.9 EEQ77341.1 - 0.074 12.1 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aldo_ket_red PF00248.16 EEQ77343.1 - 1.7e-65 220.6 0.0 3.2e-65 219.7 0.0 1.3 2 0 0 2 2 2 1 Aldo/keto reductase family Amidohydro_3 PF07969.6 EEQ77343.1 - 0.098 11.8 0.0 0.55 9.3 0.0 2.2 1 1 0 1 1 1 0 Amidohydrolase family Zn_clus PF00172.13 EEQ77344.1 - 8.4e-07 28.8 14.0 8.4e-07 28.8 9.7 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEQ77344.1 - 0.00062 18.4 5.0 0.0031 16.1 3.5 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EEQ77345.1 - 3e-05 24.0 2.5 0.0001 22.4 0.3 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ77345.1 - 0.0012 19.0 1.2 0.0012 19.0 0.9 2.4 3 0 0 3 3 3 1 C2H2-type zinc finger CAP_N PF01213.14 EEQ77345.1 - 7.1 5.8 6.9 16 4.6 4.8 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-C2H2 PF00096.21 EEQ77346.1 - 0.027 14.7 0.7 0.027 14.7 0.5 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ77346.1 - 0.1 12.9 14.6 0.27 11.6 0.6 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger MMR_HSR1 PF01926.18 EEQ77347.1 - 6.6e-17 61.5 0.2 1.4e-14 54.0 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EEQ77347.1 - 3.8e-07 29.5 0.3 0.00014 21.2 0.1 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.18 EEQ77347.1 - 0.00051 19.9 0.7 0.28 11.0 0.2 2.9 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 EEQ77347.1 - 0.00075 18.7 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EEQ77347.1 - 0.016 14.3 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Miro PF08477.8 EEQ77347.1 - 0.081 13.4 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein EST1_DNA_bind PF10373.4 EEQ77350.1 - 1.1e-06 28.1 0.1 3.3e-06 26.5 0.1 1.8 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain Glyco_tranf_2_3 PF13641.1 EEQ77350.1 - 4.6e-06 26.5 0.0 7.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EEQ77350.1 - 9.5e-06 25.3 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EEQ77350.1 - 0.0013 18.1 0.0 0.0027 17.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 EEQ77350.1 - 0.0087 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_5 PF13712.1 EEQ77350.1 - 0.035 13.3 0.0 0.077 12.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase like family EST1_DNA_bind PF10373.4 EEQ77352.1 - 0.00019 20.7 0.0 0.00035 19.8 0.0 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain Cu_bind_like PF02298.12 EEQ77354.1 - 0.13 12.0 0.1 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Plastocyanin-like domain VlpA_repeat PF04649.7 EEQ77355.1 - 0.96 9.1 4.6 0.52 10.0 0.2 2.6 2 0 0 2 2 2 0 Mycoplasma hyorhinis VlpA repeat Pol_alpha_B_N PF08418.5 EEQ77355.1 - 1.7 8.1 15.4 0.046 13.2 1.0 2.5 2 1 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Kdo PF06293.9 EEQ77356.1 - 4.4e-05 22.6 0.1 7.8e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEQ77356.1 - 0.00018 21.3 3.4 0.039 13.6 0.7 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ77356.1 - 0.016 14.8 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF3723 PF12520.3 EEQ77358.1 - 4.4e-89 299.3 2.7 3.1e-77 260.2 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) Pkinase PF00069.20 EEQ77359.1 - 6.3e-12 45.2 0.1 2e-11 43.5 0.0 1.7 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ77359.1 - 2.2e-08 33.4 0.0 3.1e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.27 EEQ77360.1 - 0.00047 19.9 0.5 0.032 14.1 0.1 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat zf-RING_2 PF13639.1 EEQ77362.1 - 0.0052 16.5 4.0 0.0095 15.7 2.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EEQ77362.1 - 0.07 13.0 4.2 0.16 11.8 3.0 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EEQ77362.1 - 0.17 11.6 2.8 1 9.1 2.1 2.0 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEQ77362.1 - 0.21 11.6 4.2 0.43 10.6 2.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ77362.1 - 0.36 10.5 2.8 0.54 9.9 1.4 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF883 PF05957.8 EEQ77363.1 - 0.99 9.8 4.9 4.7 7.6 2.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) bZIP_1 PF00170.16 EEQ77363.1 - 1.7 8.6 6.5 2.5 8.1 2.8 2.4 2 0 0 2 2 2 0 bZIP transcription factor Pkinase PF00069.20 EEQ77364.1 - 0.0066 15.6 0.0 0.0092 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EEQ77365.1 - 2.3e-10 40.6 0.0 3.8e-10 39.9 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EEQ77365.1 - 0.039 13.2 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Myb_DNA-bind_6 PF13921.1 EEQ77367.1 - 1.7e-08 34.4 5.6 6.3e-05 23.0 0.1 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEQ77367.1 - 8.6e-08 32.1 0.2 8.6e-08 32.1 0.1 4.0 3 2 0 3 3 3 1 Myb-like DNA-binding domain F-box-like PF12937.2 EEQ77368.1 - 0.00026 20.6 0.1 0.00063 19.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like DUF3435 PF11917.3 EEQ77369.1 - 2.3e-46 158.3 0.0 3.2e-45 154.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) Herpes_capsid PF06112.6 EEQ77369.1 - 0.32 11.0 3.8 4.4 7.3 0.9 2.4 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein LTV PF04180.9 EEQ77372.1 - 8.4e-72 242.9 2.9 1.1e-71 242.5 2.0 1.2 1 0 0 1 1 1 1 Low temperature viability protein PLDc_2 PF13091.1 EEQ77373.1 - 1.5e-15 57.0 0.0 4.8e-08 32.7 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EEQ77373.1 - 1.8e-08 33.9 2.1 0.0081 15.9 0.3 3.3 2 1 0 2 2 2 2 Phospholipase D Active site motif NDUFA12 PF05071.11 EEQ77374.1 - 2.1e-26 92.3 0.5 2.7e-26 92.0 0.3 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 TPR_8 PF13181.1 EEQ77375.1 - 5.3e-10 38.3 6.9 2e-05 24.0 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ77375.1 - 1.1e-08 34.9 16.9 0.22 12.2 0.0 7.8 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ77375.1 - 1.3e-08 34.3 12.9 7e-05 22.3 0.1 5.5 6 0 0 6 6 6 2 TPR repeat TPR_2 PF07719.12 EEQ77375.1 - 4.3e-08 32.4 18.5 0.039 13.8 0.1 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ77375.1 - 2.2e-06 27.8 13.9 0.0054 17.0 0.1 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ77375.1 - 3.3e-05 23.7 2.3 0.14 12.4 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ77375.1 - 0.0011 18.4 15.9 0.29 10.8 0.1 5.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ77375.1 - 0.026 15.1 0.1 0.026 15.1 0.1 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ77375.1 - 0.031 14.2 15.6 0.29 11.1 0.1 6.3 5 1 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.15 EEQ77375.1 - 0.15 12.1 1.1 75 3.6 0.0 3.6 3 0 0 3 3 3 0 PPR repeat TPR_7 PF13176.1 EEQ77375.1 - 0.39 10.6 10.4 3.9 7.4 0.1 5.2 7 0 0 7 7 6 0 Tetratricopeptide repeat MAP65_ASE1 PF03999.7 EEQ77375.1 - 0.73 8.3 11.4 0.42 9.1 6.4 1.6 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) RIX1 PF08167.7 EEQ77376.1 - 1.1e-60 204.0 6.0 1.6e-60 203.5 1.8 2.8 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis MBOAT_2 PF13813.1 EEQ77377.1 - 3.7e-21 74.9 3.8 9.2e-21 73.7 2.6 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family SNF2_N PF00176.18 EEQ77378.1 - 4.3e-70 235.8 0.0 6.4e-70 235.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EEQ77378.1 - 1.8e-16 60.0 0.0 3.3e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain zf-RING_2 PF13639.1 EEQ77378.1 - 1.9e-11 43.5 7.4 5.9e-11 42.0 5.1 1.9 1 0 0 1 1 1 1 Ring finger domain Helicase_C PF00271.26 EEQ77378.1 - 1.1e-10 41.1 0.0 2.9e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EEQ77378.1 - 3.9e-09 36.3 7.1 3.9e-09 36.3 4.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ77378.1 - 2.1e-08 33.7 8.3 2.1e-08 33.7 5.7 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEQ77378.1 - 4.5e-08 32.6 7.8 4.5e-08 32.6 5.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EEQ77378.1 - 1.3e-05 24.9 7.0 3.2e-05 23.7 4.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EEQ77378.1 - 1.6e-05 24.9 4.0 5.5e-05 23.1 2.8 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EEQ77378.1 - 2.3e-05 24.0 5.6 2.3e-05 24.0 3.9 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.3 EEQ77378.1 - 0.00027 20.3 5.3 0.00088 18.7 3.7 1.9 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 EEQ77378.1 - 0.00043 20.1 0.1 0.0025 17.7 0.0 2.2 2 0 0 2 2 2 1 U-box domain ResIII PF04851.10 EEQ77378.1 - 0.0029 17.4 0.0 0.0073 16.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.1 EEQ77378.1 - 0.0041 16.7 3.6 0.014 15.1 2.5 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EEQ77378.1 - 0.3 10.9 2.5 0.96 9.3 1.7 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Abhydrolase_3 PF07859.8 EEQ77379.1 - 2.1e-08 34.0 0.0 2.7e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold SNF2_N PF00176.18 EEQ77380.1 - 5.4e-41 140.3 6.2 3.7e-40 137.5 0.0 2.8 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ77380.1 - 1.8e-14 53.3 0.0 5.5e-14 51.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SAM_2 PF07647.12 EEQ77380.1 - 0.0025 17.5 0.0 0.0076 16.0 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) GSH_synth_ATP PF03917.12 EEQ77381.1 - 1.2e-103 346.5 0.0 1.5e-103 346.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EEQ77381.1 - 8.7e-27 93.2 0.0 1.5e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase eRF1_1 PF03463.10 EEQ77381.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 eRF1 domain 1 Aminotran_3 PF00202.16 EEQ77386.1 - 3.2e-104 348.4 0.0 3.8e-104 348.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EEQ77386.1 - 0.073 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Spt4 PF06093.8 EEQ77387.1 - 1.4e-31 108.1 0.3 1.7e-31 107.9 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Coronavirus_5 PF05528.6 EEQ77387.1 - 0.026 14.3 0.3 0.04 13.7 0.2 1.4 1 1 0 1 1 1 0 Coronavirus gene 5 protein Metallophos PF00149.23 EEQ77388.1 - 1.7e-38 132.0 0.1 2.6e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EEQ77388.1 - 2.8e-29 100.9 0.1 6.4e-29 99.8 0.1 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 EEQ77388.1 - 1.3e-18 66.3 5.3 1.4e-14 53.5 0.4 2.8 1 1 2 3 3 3 2 TPR repeat TPR_1 PF00515.23 EEQ77388.1 - 2.5e-08 33.1 5.2 0.00038 19.9 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ77388.1 - 1.4e-07 30.8 5.2 0.019 14.8 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ77388.1 - 0.00013 22.5 4.6 0.17 12.6 0.0 3.2 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ77388.1 - 0.00043 20.0 0.3 0.0018 18.1 0.1 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ77388.1 - 0.0017 18.4 0.6 2.1 8.7 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ77388.1 - 0.0019 18.4 0.6 2.4 8.5 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ77388.1 - 0.012 16.2 1.8 5.5 7.9 0.1 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ77388.1 - 0.034 14.6 1.1 7.6 7.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF89 PF01937.14 EEQ77389.1 - 5.5e-134 446.4 0.0 6.3e-134 446.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Cut12 PF11500.3 EEQ77390.1 - 1.8e-44 151.0 13.8 1.8e-44 151.0 9.6 4.1 3 1 0 3 3 3 2 Spindle pole body formation-associated protein HGTP_anticodon2 PF12745.2 EEQ77391.1 - 3.8e-83 278.7 3.1 3.8e-83 278.7 2.1 2.2 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 EEQ77391.1 - 8e-63 212.0 1.1 1.1e-25 90.3 0.0 5.1 4 2 1 5 5 5 3 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ77391.1 - 6.2e-32 110.6 0.0 3.4e-12 45.9 0.0 3.6 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 EEQ77391.1 - 1.5e-13 50.6 0.0 6.3e-13 48.6 0.0 2.2 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.1 EEQ77391.1 - 6.1e-12 45.2 1.0 1.7e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.15 EEQ77391.1 - 3.8e-05 23.5 0.1 0.00011 22.0 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain Kinase-like PF14531.1 EEQ77391.1 - 0.00042 19.3 0.0 0.083 11.8 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EEQ77391.1 - 0.0021 17.8 6.0 0.0026 17.5 0.0 3.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family UPF0075 PF03702.9 EEQ77391.1 - 0.22 10.3 0.0 0.47 9.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) RRM_1 PF00076.17 EEQ77392.1 - 2.3e-08 33.5 0.0 4.1e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ77392.1 - 1.5e-06 27.9 0.0 2.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ77392.1 - 0.00014 21.7 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEQ77392.1 - 0.0025 17.5 0.0 0.0049 16.6 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif TGS PF02824.16 EEQ77393.1 - 2.4e-21 75.2 0.4 4.8e-21 74.3 0.1 1.7 2 0 0 2 2 2 1 TGS domain MMR_HSR1 PF01926.18 EEQ77393.1 - 1.1e-18 67.2 0.1 3.4e-18 65.6 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEQ77393.1 - 8.4e-13 47.8 0.0 1.3e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EEQ77393.1 - 0.00042 20.1 0.3 0.99 9.2 0.2 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EEQ77393.1 - 0.0057 17.1 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 EEQ77393.1 - 0.048 12.4 0.1 0.11 11.2 0.1 1.6 1 0 0 1 1 1 0 ArgK protein MCM PF00493.18 EEQ77393.1 - 0.08 11.7 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family AIG1 PF04548.11 EEQ77393.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 AIG1 family AAA_17 PF13207.1 EEQ77393.1 - 0.16 12.7 0.8 0.7 10.7 0.6 2.3 1 1 0 1 1 1 0 AAA domain CTDII PF01556.13 EEQ77394.1 - 5.4e-23 80.7 0.7 2.9e-21 75.1 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 EEQ77394.1 - 3.9e-20 71.3 10.4 1.2e-14 53.7 0.9 3.1 2 1 1 3 3 3 2 DnaJ domain PIG-X PF08320.7 EEQ77395.1 - 6.4e-74 247.7 0.0 8.5e-74 247.2 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 RFX_DNA_binding PF02257.10 EEQ77396.1 - 6.6e-30 103.0 0.1 1.4e-29 102.0 0.1 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain TB2_DP1_HVA22 PF03134.14 EEQ77397.1 - 1.4e-30 104.8 8.0 2e-30 104.3 5.5 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Kei1 PF08552.6 EEQ77397.1 - 0.28 10.8 5.8 0.2 11.3 1.9 2.1 1 1 1 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 DUF1649 PF07855.7 EEQ77398.1 - 2.4e-64 215.9 0.0 2.8e-64 215.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) DUF1814 PF08843.6 EEQ77399.1 - 1e-05 25.4 0.0 1.1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) DUF2204 PF09970.4 EEQ77399.1 - 0.0014 18.1 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) Polyhedrin PF00738.13 EEQ77400.1 - 0.084 11.9 0.0 0.099 11.6 0.0 1.2 1 0 0 1 1 1 0 Polyhedrin Peroxin-3 PF04882.7 EEQ77401.1 - 8e-145 482.8 3.0 1e-144 482.4 2.1 1.1 1 0 0 1 1 1 1 Peroxin-3 RNA_binding PF01877.12 EEQ77401.1 - 0.097 12.6 0.3 3.6 7.6 0.0 2.5 2 0 0 2 2 2 0 RNA binding Na_H_Exchanger PF00999.16 EEQ77402.1 - 2.5e-67 227.0 42.1 3.7e-67 226.5 29.2 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Usp PF00582.21 EEQ77402.1 - 0.077 13.1 0.2 1.2 9.3 0.1 2.7 2 2 0 2 2 2 0 Universal stress protein family MFS_1 PF07690.11 EEQ77403.1 - 1.7e-29 102.6 25.8 3.8e-29 101.5 17.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily ThiF PF00899.16 EEQ77405.1 - 2.6e-08 33.7 0.6 5.9e-07 29.3 0.4 2.4 1 1 0 1 1 1 1 ThiF family CENP-M PF11111.3 EEQ77405.1 - 0.0042 16.3 0.4 0.049 12.8 0.0 2.2 1 1 1 2 2 2 1 Centromere protein M (CENP-M) Pterin_bind PF00809.17 EEQ77405.1 - 0.064 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Pterin binding enzyme Ytp1 PF10355.4 EEQ77406.1 - 8.5e-88 294.0 15.6 8.5e-88 294.0 10.8 2.1 2 0 0 2 2 2 2 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EEQ77406.1 - 1.2e-33 114.7 4.0 1.2e-33 114.7 2.8 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) Swi5 PF07061.6 EEQ77407.1 - 1.5e-27 95.2 0.0 2e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Swi5 Tropomyosin_1 PF12718.2 EEQ77407.1 - 5.3e-05 23.1 0.1 7.2e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 Tropomyosin like DUF4200 PF13863.1 EEQ77407.1 - 0.018 15.0 0.2 0.026 14.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) TMF_DNA_bd PF12329.3 EEQ77407.1 - 0.089 12.6 1.6 0.13 12.0 1.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EEQ77408.1 - 0.017 14.7 3.1 0.034 13.7 2.2 1.5 1 0 0 1 1 1 0 IncA protein COG2 PF06148.6 EEQ77408.1 - 0.47 10.3 6.1 1 9.2 4.2 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF342 PF03961.8 EEQ77408.1 - 9.1 4.5 6.8 13 4.0 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Cyclin_N PF00134.18 EEQ77409.1 - 0.0025 17.3 0.0 0.061 12.9 0.0 2.7 2 1 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 EEQ77409.1 - 0.0029 17.3 0.0 0.29 10.9 0.0 2.6 2 1 0 2 2 2 2 Transcription factor TFIIB repeat Autophagy_N PF03986.8 EEQ77411.1 - 3.4e-48 163.1 0.0 6.4e-48 162.2 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EEQ77411.1 - 2.3e-19 69.3 0.0 5.8e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EEQ77411.1 - 2.1e-14 52.2 0.5 3.6e-14 51.5 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Nucleoplasmin PF03066.10 EEQ77411.1 - 5.6 6.4 7.6 3.4 7.1 3.6 1.7 2 0 0 2 2 2 0 Nucleoplasmin DUF4482 PF14818.1 EEQ77412.1 - 0.045 14.4 1.2 0.045 14.4 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) Striatin PF08232.7 EEQ77412.1 - 0.082 13.2 7.7 0.041 14.1 3.2 1.9 2 0 0 2 2 2 0 Striatin family TPR_MLP1_2 PF07926.7 EEQ77412.1 - 0.2 11.4 1.2 0.36 10.5 0.8 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Glycos_transf_2 PF00535.21 EEQ77413.1 - 7.4e-22 77.8 0.0 6.4e-11 42.2 0.0 2.7 1 1 1 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EEQ77413.1 - 3.8e-06 26.8 0.1 0.19 11.5 0.0 3.4 2 1 1 3 3 3 2 Glycosyltransferase like family 2 LrgB PF04172.11 EEQ77413.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 LrgB-like family EST1_DNA_bind PF10373.4 EEQ77415.1 - 0.00013 21.3 0.4 0.00019 20.7 0.3 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain zf-C3HC4_3 PF13920.1 EEQ77419.1 - 3.4e-12 45.8 7.8 5.1e-12 45.2 5.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ77419.1 - 5e-09 36.0 3.9 3e-08 33.5 3.0 1.9 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ77419.1 - 3.9e-06 26.5 7.5 6.2e-06 25.9 5.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EEQ77419.1 - 4e-06 26.3 2.8 9e-06 25.2 2.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ77419.1 - 6e-05 22.6 6.0 9.7e-05 22.0 4.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EEQ77419.1 - 0.067 13.0 3.3 0.27 11.1 2.6 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EEQ77419.1 - 0.38 10.3 4.3 0.97 9.0 1.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Elf1 PF05129.8 EEQ77419.1 - 0.44 10.2 3.6 0.58 9.8 0.4 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-RING_4 PF14570.1 EEQ77419.1 - 0.82 9.3 5.5 1.8 8.2 3.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EEQ77419.1 - 2.1 8.1 7.3 1.8 8.3 1.4 2.5 2 0 0 2 2 2 0 RING-type zinc-finger NUDIX PF00293.23 EEQ77420.1 - 0.003 17.1 0.1 0.0075 15.9 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain NUDIX PF00293.23 EEQ77421.1 - 2.6e-17 62.7 0.0 4e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF3433 PF11915.3 EEQ77422.1 - 2.6e-39 133.2 9.7 4.7e-22 77.9 0.2 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) HAD_2 PF13419.1 EEQ77423.1 - 3.2e-15 56.7 0.0 4.2e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEQ77423.1 - 6.7e-06 26.6 0.0 2.5e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ77423.1 - 2.5e-05 23.8 0.0 4.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.13 EEQ77423.1 - 0.00011 21.9 0.0 0.0061 16.2 0.0 2.2 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase HAD PF12710.2 EEQ77423.1 - 0.0025 18.0 0.0 0.0037 17.4 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Methyltransf_33 PF10017.4 EEQ77423.1 - 0.038 13.8 0.1 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent MutS_III PF05192.13 EEQ77423.1 - 0.13 11.9 0.1 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 MutS domain III F-box PF00646.28 EEQ77425.1 - 0.0011 18.5 0.4 0.004 16.7 0.3 2.0 1 0 0 1 1 1 1 F-box domain Init_tRNA_PT PF04179.7 EEQ77426.1 - 1.5e-168 561.3 0.0 1.7e-168 561.1 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase RVT_1 PF00078.22 EEQ77427.1 - 5.8e-09 35.6 0.0 1.2e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_int_SAM_4 PF13495.1 EEQ77427.1 - 0.042 14.1 2.4 0.39 11.0 0.2 2.9 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain PhyH PF05721.8 EEQ77427.1 - 0.052 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Transp_cyt_pur PF02133.10 EEQ77429.1 - 5.6e-130 433.8 41.4 3.3e-128 428.0 28.7 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Urb2 PF10441.4 EEQ77431.1 - 1.2e-63 214.7 0.6 4.8e-63 212.7 0.0 2.4 2 0 0 2 2 2 1 Urb2/Npa2 family RICH PF05062.7 EEQ77431.1 - 2.1 8.5 6.0 1.9 8.6 0.1 2.9 2 0 0 2 2 2 0 RICH domain DUF543 PF04418.7 EEQ77432.1 - 8.2e-26 89.7 0.1 8.9e-26 89.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Copper-fist PF00649.13 EEQ77433.1 - 3.2e-19 67.8 0.3 1e-18 66.2 0.2 2.0 1 0 0 1 1 1 1 Copper fist DNA binding domain Tom37 PF10568.4 EEQ77434.1 - 1.2e-06 28.6 0.0 2.5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Tom37_C PF11801.3 EEQ77434.1 - 4.1e-05 23.5 1.0 0.013 15.3 0.1 2.2 2 0 0 2 2 2 2 Tom37 C-terminal domain DUF2731 PF10806.3 EEQ77434.1 - 0.00022 21.4 0.0 0.00095 19.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2731) GST_C_3 PF14497.1 EEQ77434.1 - 0.00023 21.5 0.1 0.00038 20.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEQ77434.1 - 0.0052 16.6 0.2 0.012 15.4 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Methyltransf_23 PF13489.1 EEQ77435.1 - 6.7e-11 42.1 0.0 9.1e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ77435.1 - 1.2e-10 41.9 0.0 2.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ77435.1 - 2.2e-10 40.8 0.0 4.7e-10 39.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ77435.1 - 8.3e-09 35.2 0.0 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ77435.1 - 5.3e-08 33.2 0.0 1.5e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ77435.1 - 3e-06 27.5 0.0 6.7e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ77435.1 - 4.9e-06 25.8 0.0 6.3e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EEQ77435.1 - 1e-05 24.7 0.0 2.2e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EEQ77435.1 - 5.4e-05 22.6 0.0 0.00015 21.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EEQ77435.1 - 6.5e-05 22.9 0.1 0.00013 21.9 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EEQ77435.1 - 0.00042 19.9 0.0 0.00054 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EEQ77435.1 - 0.038 13.6 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EEQ77435.1 - 0.086 11.8 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 EEQ77435.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB ADH_zinc_N PF00107.21 EEQ77435.1 - 0.26 10.8 1.6 1.2 8.6 0.1 2.5 1 1 1 2 2 2 0 Zinc-binding dehydrogenase CDC14 PF08045.6 EEQ77436.1 - 1.3e-99 332.5 0.0 1.5e-99 332.3 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Paramyxo_PCT PF14320.1 EEQ77437.1 - 0.063 12.1 0.0 0.093 11.6 0.0 1.1 1 0 0 1 1 1 0 Phosphoprotein P region PCT disordered Sugar_tr PF00083.19 EEQ77438.1 - 1.3e-83 281.1 22.4 1.5e-83 280.9 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ77438.1 - 5.7e-15 54.8 35.9 7.1e-11 41.4 18.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily polyprenyl_synt PF00348.12 EEQ77440.1 - 1.5e-59 201.0 0.0 2e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase NACHT PF05729.7 EEQ77440.1 - 0.035 13.7 0.0 0.087 12.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Beta_elim_lyase PF01212.16 EEQ77441.1 - 6.2e-79 265.1 0.0 8.5e-79 264.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EEQ77441.1 - 2.1e-05 23.6 0.0 4.3e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EEQ77441.1 - 0.00011 20.6 0.0 0.00015 20.1 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EEQ77441.1 - 0.0087 15.1 0.1 0.049 12.6 0.0 2.0 2 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Peptidase_M24 PF00557.19 EEQ77442.1 - 6.5e-18 65.0 0.0 9.2e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EEQ77442.1 - 1.6e-16 60.9 0.0 2.7e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain AA_permease PF00324.16 EEQ77443.1 - 3.4e-92 309.2 36.7 4.1e-92 309.0 25.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ77443.1 - 1.3e-16 60.2 37.8 2.2e-16 59.4 26.2 1.3 1 1 0 1 1 1 1 Amino acid permease Peptidase_M20 PF01546.23 EEQ77444.1 - 1.9e-24 86.2 0.0 3e-24 85.5 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EEQ77444.1 - 3e-13 49.4 0.1 6.2e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF3226 PF11536.3 EEQ77444.1 - 0.15 11.5 0.1 2.8 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3226) DUF1771 PF08590.5 EEQ77445.1 - 1.7e-22 79.2 8.8 1.7e-22 79.2 6.1 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1771) Smr PF01713.16 EEQ77445.1 - 1.9e-16 60.0 0.5 6e-16 58.4 0.2 2.0 2 0 0 2 2 2 1 Smr domain PspA_IM30 PF04012.7 EEQ77445.1 - 0.24 10.7 4.9 0.11 11.8 1.5 1.8 2 0 0 2 2 2 0 PspA/IM30 family A_deaminase PF00962.17 EEQ77446.1 - 3.3e-29 101.8 0.0 4.4e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase RepA_N PF06970.6 EEQ77447.1 - 0.012 15.3 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus zf-C2H2 PF00096.21 EEQ77449.1 - 2.1e-07 30.8 14.1 0.0018 18.4 0.3 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ77449.1 - 4e-07 29.8 10.4 0.027 14.7 0.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EEQ77449.1 - 0.00065 19.8 9.6 0.26 11.6 0.2 3.6 3 0 0 3 3 3 2 Zinc-finger double domain FSIP1 PF15554.1 EEQ77449.1 - 0.0069 15.2 0.8 0.0095 14.7 0.5 1.2 1 0 0 1 1 1 1 FSIP1 family IncA PF04156.9 EEQ77449.1 - 0.18 11.4 0.8 0.3 10.6 0.6 1.3 1 0 0 1 1 1 0 IncA protein Transpos_assoc PF13963.1 EEQ77449.1 - 0.28 11.2 3.2 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Transposase-associated domain DSPc PF00782.15 EEQ77452.1 - 3.4e-10 39.6 0.0 2.7e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain YjeF_N PF03853.10 EEQ77452.1 - 0.00035 20.2 0.0 0.00086 18.9 0.0 1.6 2 0 0 2 2 2 1 YjeF-related protein N-terminus Init_tRNA_PT PF04179.7 EEQ77452.1 - 0.076 11.8 0.1 0.093 11.5 0.1 1.2 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase SNF2_N PF00176.18 EEQ77454.1 - 4e-66 222.8 0.7 2e-65 220.5 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ77454.1 - 4.1e-17 61.8 0.2 2.2e-16 59.5 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EEQ77454.1 - 0.00043 19.2 0.6 0.0032 16.3 0.0 2.7 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 End3 PF12761.2 EEQ77455.1 - 1e-75 253.6 0.2 1.5e-75 253.1 0.2 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 EEQ77455.1 - 5.8e-53 177.0 0.1 8.9e-50 166.7 0.1 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EEQ77455.1 - 3.7e-08 32.1 0.2 2.9e-07 29.3 0.2 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EEQ77455.1 - 4.5e-07 29.3 0.0 6.6e-05 22.4 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 EEQ77455.1 - 1.2e-06 28.5 0.0 6.6e-05 22.9 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 EEQ77455.1 - 1.7e-06 27.4 0.0 0.00021 20.9 0.2 3.0 3 0 0 3 3 2 1 EF-hand domain EF-hand_5 PF13202.1 EEQ77455.1 - 0.00083 18.5 0.2 0.0026 17.0 0.2 1.8 1 0 0 1 1 1 1 EF hand Rabaptin PF03528.10 EEQ77455.1 - 0.023 14.6 1.6 0.023 14.6 1.1 2.7 1 1 1 2 2 2 0 Rabaptin TPR_MLP1_2 PF07926.7 EEQ77455.1 - 0.09 12.5 0.4 0.09 12.5 0.3 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.1 EEQ77455.1 - 0.091 11.7 2.4 0.15 10.9 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) COG2 PF06148.6 EEQ77455.1 - 0.31 10.8 2.8 2.9 7.7 0.1 2.7 3 0 0 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TPD52 PF04201.10 EEQ77455.1 - 0.39 10.4 6.3 3.4 7.3 0.1 2.3 2 0 0 2 2 2 0 Tumour protein D52 family Spc7 PF08317.6 EEQ77455.1 - 1.7 7.1 6.2 4.8 5.7 4.1 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 EEQ77455.1 - 3.8 7.3 9.9 11 5.8 0.5 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF947 PF06102.7 EEQ77455.1 - 5.4 6.7 7.0 0.98 9.2 1.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF947) Mit_KHE1 PF10173.4 EEQ77456.1 - 1e-66 224.3 0.3 1.3e-66 224.0 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related MARVEL PF01284.18 EEQ77457.1 - 0.028 14.2 2.6 0.053 13.3 1.8 1.4 1 1 0 1 1 1 0 Membrane-associating domain Cupin_1 PF00190.17 EEQ77458.1 - 9.9e-06 25.0 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EEQ77458.1 - 3.2e-05 23.3 0.2 5.2e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Cupin domain ARD PF03079.9 EEQ77458.1 - 0.00042 20.3 0.0 0.00044 20.2 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.2 EEQ77458.1 - 0.082 12.5 0.0 0.098 12.2 0.0 1.1 1 0 0 1 1 1 0 Cupin Cullin PF00888.17 EEQ77459.1 - 5.4e-200 665.8 7.9 8.8e-200 665.1 5.5 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EEQ77459.1 - 5.1e-28 96.7 3.6 5.1e-28 96.7 2.5 2.7 3 0 0 3 3 3 1 Cullin protein neddylation domain Abi_C PF14355.1 EEQ77459.1 - 0.071 13.0 0.0 0.3 11.0 0.0 2.0 1 0 0 1 1 1 0 Abortive infection C-terminus WGG PF10273.4 EEQ77459.1 - 0.1 12.6 1.6 33 4.6 0.0 3.7 3 0 0 3 3 3 0 Pre-rRNA-processing protein TSR2 HNH_2 PF13391.1 EEQ77460.1 - 1.7e-11 43.7 0.5 4.5e-11 42.3 0.4 1.7 1 0 0 1 1 1 1 HNH endonuclease Anophelin PF10731.4 EEQ77460.1 - 0.15 12.1 7.2 4.8 7.3 0.4 2.7 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito GCV_T PF01571.16 EEQ77461.1 - 0.071 12.4 0.0 0.071 12.4 0.0 1.1 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain PapD-like PF14874.1 EEQ77461.1 - 0.2 11.5 0.6 0.31 10.9 0.4 1.2 1 0 0 1 1 1 0 Flagellar-associated PapD-like G-alpha PF00503.15 EEQ77463.1 - 4.5e-122 407.5 0.0 5.3e-122 407.2 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EEQ77463.1 - 1.8e-15 56.5 1.3 2e-10 40.1 0.2 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEQ77463.1 - 0.00011 21.4 0.2 0.2 10.7 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EEQ77463.1 - 0.0013 19.1 0.1 0.52 10.8 0.0 2.6 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 EEQ77463.1 - 0.046 13.2 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain APH PF01636.18 EEQ77464.1 - 2.1e-07 30.9 0.5 3.7e-07 30.1 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ77464.1 - 0.019 14.0 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kp4 PF09044.5 EEQ77465.1 - 1e-16 60.8 2.4 1.4e-16 60.4 1.6 1.1 1 0 0 1 1 1 1 Kp4 APH PF01636.18 EEQ77466.1 - 6e-17 62.1 0.0 8.1e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ77466.1 - 0.00012 21.7 0.0 0.00021 20.9 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EEQ77466.1 - 0.00022 19.9 1.6 0.014 14.0 0.2 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.9 EEQ77466.1 - 0.0069 15.3 0.0 0.016 14.2 0.0 1.4 1 1 0 1 1 1 1 Fructosamine kinase Pkinase PF00069.20 EEQ77468.1 - 3.5e-66 223.0 0.0 1.7e-65 220.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ77468.1 - 2.7e-26 92.1 0.0 3.5e-20 72.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEQ77468.1 - 1.7e-05 23.9 0.0 2.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEQ77468.1 - 0.00014 21.6 0.0 0.0007 19.4 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ77468.1 - 0.00016 20.7 0.0 0.0092 15.0 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EEQ77468.1 - 0.046 13.0 0.0 0.093 12.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Avl9 PF09794.4 EEQ77469.1 - 1e-117 392.8 0.1 1.8e-117 392.0 0.0 1.4 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 EEQ77469.1 - 3.2e-06 26.8 0.0 1.3e-05 24.8 0.0 2.0 2 1 0 2 2 2 1 Stabilization of polarity axis DUF2347 PF09804.4 EEQ77469.1 - 0.00019 20.8 4.4 0.00055 19.2 0.4 3.2 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Glyco_hydro_47 PF01532.15 EEQ77470.1 - 8.6e-164 545.4 0.0 1e-163 545.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4038 PF13204.1 EEQ77470.1 - 5.6e-05 22.6 0.0 0.00012 21.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) 4HBT PF03061.17 EEQ77471.1 - 4.3e-10 39.5 0.1 6.8e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EEQ77471.1 - 0.0019 17.9 0.1 0.0025 17.6 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily MaoC_dehydratas PF01575.14 EEQ77471.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain DUF3888 PF13027.1 EEQ77471.1 - 0.035 13.9 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3888) DUF2808 PF10989.3 EEQ77471.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) Phosphorylase PF00343.15 EEQ77472.1 - 0 1079.8 0.1 0 1079.6 0.1 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Zn_clus PF00172.13 EEQ77473.1 - 3.4e-08 33.2 6.3 7.1e-08 32.2 4.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 EEQ77474.1 - 3.3e-07 30.0 0.0 1.3e-06 28.1 0.0 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ77474.1 - 3.4e-07 29.8 0.2 7.3e-07 28.7 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEQ77474.1 - 0.021 15.7 0.1 0.048 14.5 0.1 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EEQ77474.1 - 0.096 12.2 0.5 0.15 11.6 0.3 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ABC_membrane_2 PF06472.10 EEQ77475.1 - 2.3e-109 364.8 1.6 3.6e-109 364.2 1.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EEQ77475.1 - 4.9e-19 68.9 0.0 8.9e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EEQ77475.1 - 0.00012 22.1 0.0 0.00037 20.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EEQ77475.1 - 0.0068 16.7 0.0 0.027 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EEQ77475.1 - 0.017 14.6 0.0 0.043 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.14 EEQ77475.1 - 0.043 13.0 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EEQ77475.1 - 0.043 13.8 0.2 0.15 12.0 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EEQ77475.1 - 0.15 11.2 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 LRR_6 PF13516.1 EEQ77476.1 - 0.007 16.3 4.0 62 4.1 0.1 6.1 6 0 0 6 6 6 0 Leucine Rich repeat DUF3356 PF11836.3 EEQ77476.1 - 0.013 15.2 0.3 0.031 14.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3356) LRR_4 PF12799.2 EEQ77476.1 - 0.045 13.3 1.9 2.5 7.8 0.3 4.4 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EEQ77476.1 - 0.4 10.8 8.4 62 4.2 0.0 6.4 7 1 1 8 8 8 0 Leucine Rich Repeat Ribosomal_L18p PF00861.17 EEQ77478.1 - 1.2e-41 141.5 0.1 1.2e-41 141.5 0.1 1.8 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EEQ77478.1 - 1.2e-33 115.4 7.7 1.2e-33 115.4 5.3 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Metal_resist PF13801.1 EEQ77478.1 - 0.057 13.4 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Heavy-metal resistance DUF4284 PF14112.1 EEQ77478.1 - 0.85 10.1 4.1 0.6 10.6 0.4 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4284) HAD_2 PF13419.1 EEQ77479.1 - 4.9e-16 59.4 0.0 1.1e-15 58.2 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEQ77479.1 - 0.00028 20.5 0.0 0.00055 19.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like FTA4 PF13093.1 EEQ77480.1 - 3.5e-75 252.1 3.1 4.1e-75 251.8 2.2 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Antitoxin-MazE PF04014.13 EEQ77480.1 - 0.016 14.9 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 Antidote-toxin recognition MazE PAP1 PF08601.5 EEQ77481.1 - 0.033 13.8 1.7 0.041 13.5 1.2 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 SlyX PF04102.7 EEQ77481.1 - 0.035 14.4 2.2 0.083 13.2 0.4 2.4 2 0 0 2 2 2 0 SlyX HAUS6_N PF14661.1 EEQ77481.1 - 0.82 8.9 5.2 1.3 8.2 3.6 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus AA_permease PF00324.16 EEQ77482.1 - 4.6e-121 404.4 32.0 5.5e-121 404.2 22.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ77482.1 - 6.8e-34 117.1 36.0 9.1e-34 116.7 25.0 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4468 PF14730.1 EEQ77484.1 - 0.078 12.6 0.4 0.096 12.3 0.3 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4468) with TBP-like fold Coatomer_E PF04733.9 EEQ77487.1 - 5.2e-64 216.2 1.8 5.9e-64 216.0 1.2 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 EEQ77487.1 - 8.4e-09 35.6 7.8 0.00094 19.4 1.9 3.7 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ77487.1 - 1.4e-06 28.7 7.5 0.11 13.2 0.0 3.9 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ77487.1 - 1.8e-05 24.9 9.8 0.061 13.9 0.0 4.6 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ77487.1 - 3.3e-05 23.7 1.6 0.016 15.1 0.1 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ77487.1 - 0.00019 20.9 0.5 1.8 8.3 0.1 3.4 3 1 0 3 3 3 2 TPR repeat TPR_6 PF13174.1 EEQ77487.1 - 0.00022 21.4 0.2 0.6 10.6 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ77487.1 - 0.00066 19.1 0.0 0.13 11.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EEQ77487.1 - 0.0013 18.8 0.0 0.2 11.8 0.1 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EEQ77487.1 - 0.0016 18.5 0.0 0.56 10.5 0.0 3.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_20 PF14561.1 EEQ77487.1 - 0.0075 16.3 5.2 0.027 14.5 0.3 3.4 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ77487.1 - 0.04 13.8 9.8 0.087 12.7 0.0 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ77487.1 - 0.11 12.3 1.7 33 4.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1020 PF06255.8 EEQ77487.1 - 0.12 11.5 1.2 0.18 10.9 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1020) TPR_10 PF13374.1 EEQ77487.1 - 0.65 10.0 4.6 6.3 6.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.8 EEQ77488.1 - 2.3e-24 86.1 0.0 3.7e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EEQ77488.1 - 1.4e-21 76.5 0.0 1.8e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EEQ77488.1 - 0.012 14.8 0.0 0.027 13.7 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family PMI_typeI PF01238.16 EEQ77489.1 - 4.5e-145 483.3 0.0 5.5e-145 483.0 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I DUF1325 PF07039.6 EEQ77490.1 - 1.8e-27 95.5 0.0 3.5e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain GTP_cyclohydro2 PF00925.15 EEQ77491.1 - 2.4e-55 186.3 0.1 3.2e-50 169.6 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II Methyltransf_23 PF13489.1 EEQ77492.1 - 8.2e-10 38.6 0.4 1.5e-09 37.7 0.2 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ77492.1 - 1.2e-07 31.4 0.0 4.1e-07 29.7 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ77492.1 - 2.5e-05 24.8 0.0 5.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ77492.1 - 4.3e-05 23.9 0.0 0.00014 22.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EEQ77492.1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ77492.1 - 0.027 14.9 0.0 0.18 12.3 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain SelP_N PF04592.9 EEQ77492.1 - 1.4 8.2 10.5 2.2 7.6 7.3 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF3425 PF11905.3 EEQ77494.1 - 1.7e-36 125.0 3.8 3.2e-36 124.2 2.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EEQ77494.1 - 0.0018 18.1 11.8 0.0052 16.7 8.2 1.7 1 1 0 1 1 1 1 bZIP transcription factor BMFP PF04380.8 EEQ77494.1 - 1.4 9.0 6.7 0.21 11.7 1.9 1.7 2 0 0 2 2 2 0 Membrane fusogenic activity Actin PF00022.14 EEQ77497.1 - 1.3e-117 392.5 0.0 1.8e-117 392.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EEQ77497.1 - 0.042 12.4 0.0 0.24 9.9 0.0 2.2 1 1 0 1 1 1 0 MreB/Mbl protein EamA PF00892.15 EEQ77498.1 - 2.4e-11 43.7 28.7 5.9e-06 26.3 1.5 2.6 3 0 0 3 3 3 2 EamA-like transporter family PgaD PF13994.1 EEQ77498.1 - 0.00016 21.1 0.4 0.00016 21.1 0.3 2.3 1 1 1 2 2 2 1 PgaD-like protein EmrE PF13536.1 EEQ77498.1 - 0.00067 19.8 1.7 0.00067 19.8 1.2 2.6 2 1 0 2 2 2 1 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 EEQ77498.1 - 0.0016 17.5 2.0 0.0052 15.9 0.3 2.4 2 1 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.11 EEQ77498.1 - 0.016 14.8 16.9 0.11 12.1 6.7 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family Aldo_ket_red PF00248.16 EEQ77500.1 - 3.7e-55 186.7 0.0 4.2e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SLAC1 PF03595.12 EEQ77501.1 - 1.1e-96 323.3 55.8 1.3e-96 323.1 38.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Asp_Glu_race PF01177.17 EEQ77502.1 - 5.7e-14 52.5 0.0 1e-13 51.6 0.0 1.4 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Tubulin PF00091.20 EEQ77503.1 - 3e-73 246.2 0.0 4.4e-73 245.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EEQ77503.1 - 3.7e-41 140.0 0.6 6.5e-41 139.3 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EEQ77503.1 - 3.4e-07 30.3 0.0 8.2e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain DUF883 PF05957.8 EEQ77504.1 - 0.038 14.3 1.6 0.053 13.9 1.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 EEQ77504.1 - 0.08 13.3 2.5 0.11 12.9 1.7 1.2 1 0 0 1 1 1 0 YtxH-like protein HSP9_HSP12 PF04119.7 EEQ77504.1 - 0.11 12.5 7.6 0.29 11.2 4.5 2.0 1 1 1 2 2 2 0 Heat shock protein 9/12 MT0933_antitox PF14013.1 EEQ77504.1 - 0.37 10.9 5.7 9.6 6.4 3.6 2.5 1 1 1 2 2 2 0 MT0933-like antitoxin protein AF-4 PF05110.8 EEQ77504.1 - 2.6 5.8 8.8 2.8 5.6 6.1 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Dodecin PF07311.7 EEQ77504.1 - 3 7.9 7.5 3.3 7.8 2.5 2.1 1 1 1 2 2 2 0 Dodecin Robl_LC7 PF03259.12 EEQ77505.1 - 3.7e-06 26.3 0.1 0.11 12.0 0.0 3.2 3 0 0 3 3 3 2 Roadblock/LC7 domain MRI PF15325.1 EEQ77505.1 - 0.0063 17.4 2.0 0.0063 17.4 1.4 2.2 1 1 0 2 2 2 1 Modulator of retrovirus infection PAT1 PF09770.4 EEQ77505.1 - 0.27 9.4 3.3 0.26 9.4 2.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ipi1_N PF12333.3 EEQ77506.1 - 4.8e-30 103.5 0.2 1.5e-28 98.7 0.0 2.5 2 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation CLASP_N PF12348.3 EEQ77506.1 - 0.026 13.8 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 CLASP N terminal HEAT PF02985.17 EEQ77506.1 - 0.049 13.7 0.3 4.2 7.7 0.1 3.5 3 0 0 3 3 3 0 HEAT repeat NfI_DNAbd_pre-N PF10524.4 EEQ77506.1 - 0.071 12.7 0.0 0.32 10.6 0.0 2.0 2 0 0 2 2 2 0 Nuclear factor I protein pre-N-terminus Pyrid_oxidase_2 PF13883.1 EEQ77509.1 - 5.4e-35 120.6 0.0 7.8e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Cyclin PF08613.6 EEQ77510.1 - 4.4e-09 36.9 0.0 1.6e-08 35.0 0.0 2.0 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EEQ77510.1 - 0.022 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain Sigma_reg_C PF13791.1 EEQ77511.1 - 0.13 12.3 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Sigma factor regulator C-terminal EIID-AGA PF03613.9 EEQ77511.1 - 0.19 10.6 2.4 0.34 9.8 0.0 1.9 2 0 0 2 2 2 0 PTS system mannose/fructose/sorbose family IID component FMO-like PF00743.14 EEQ77514.1 - 3.6e-99 332.3 0.0 4.5e-99 332.0 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EEQ77514.1 - 5.7e-24 85.3 0.0 1.6e-23 83.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEQ77514.1 - 1.1e-08 34.3 0.1 5.1e-05 22.3 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EEQ77514.1 - 2.3e-07 30.7 3.9 0.00012 21.8 0.2 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EEQ77514.1 - 4.3e-06 26.7 0.0 1.3e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEQ77514.1 - 1.9e-05 24.5 0.0 4.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEQ77514.1 - 0.00014 20.8 0.1 0.027 13.4 0.0 2.7 4 0 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EEQ77514.1 - 0.00079 19.7 1.4 0.093 13.1 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EEQ77514.1 - 0.0044 16.1 0.1 2.2 7.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_7 PF13241.1 EEQ77514.1 - 0.019 15.2 0.3 8.5 6.6 0.0 2.9 2 1 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.9 EEQ77514.1 - 0.025 13.0 0.1 0.076 11.4 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 EEQ77514.1 - 0.029 13.4 0.2 0.057 12.5 0.1 1.5 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 EEQ77514.1 - 0.037 13.1 0.0 0.12 11.3 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EEQ77514.1 - 0.16 10.5 0.1 2.2 6.8 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase Abhydrolase_3 PF07859.8 EEQ77515.1 - 2.6e-58 197.0 0.1 3.5e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEQ77515.1 - 9.8e-05 21.6 0.0 0.00047 19.4 0.0 1.9 1 1 1 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.23 EEQ77515.1 - 0.00033 19.5 1.2 0.00094 18.0 0.8 1.6 1 1 0 1 1 1 1 Carboxylesterase family Lyase_1 PF00206.15 EEQ77516.1 - 6.5e-114 380.3 0.0 1.1e-113 379.6 0.0 1.4 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EEQ77516.1 - 3.4e-22 78.2 0.0 1.2e-21 76.4 0.0 2.0 1 0 0 1 1 1 1 Fumarase C C-terminus Acetyltransf_1 PF00583.19 EEQ77518.1 - 2.9e-08 33.6 0.0 4.6e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ77518.1 - 3.7e-08 33.4 0.2 5.9e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Thiolase_C PF02803.13 EEQ77518.1 - 0.13 11.6 0.0 3.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Thiolase, C-terminal domain FAD_binding_4 PF01565.18 EEQ77521.1 - 5.4e-17 61.5 3.0 7.9e-16 57.7 3.0 2.2 2 1 0 2 2 2 1 FAD binding domain BBE PF08031.7 EEQ77521.1 - 0.00068 19.4 0.3 0.0015 18.3 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like His_biosynth PF00977.16 EEQ77522.1 - 3.1e-33 114.9 0.0 3.7e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 EEQ77522.1 - 0.0099 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family DUF4602 PF15375.1 EEQ77523.1 - 0.057 13.4 9.0 0.18 11.8 6.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4602) Pex14_N PF04695.8 EEQ77524.1 - 0.0016 18.5 1.6 0.0062 16.5 1.6 1.6 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region MGC-24 PF05283.6 EEQ77524.1 - 0.012 15.4 0.7 0.018 14.8 0.5 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Pyocin_S PF06958.7 EEQ77524.1 - 0.019 15.3 6.4 0.076 13.3 3.7 2.0 2 0 0 2 2 2 0 S-type Pyocin Trypan_PARP PF05887.6 EEQ77524.1 - 0.025 14.3 5.0 0.043 13.6 3.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Plasmodium_Vir PF05795.6 EEQ77524.1 - 0.036 13.2 0.0 0.044 12.9 0.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SKG6 PF08693.5 EEQ77524.1 - 0.1 11.9 0.3 0.2 11.0 0.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.1 EEQ77524.1 - 0.14 12.5 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MSA-2c PF12238.3 EEQ77524.1 - 1.2 8.8 7.8 1.7 8.3 5.4 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF605 PF04652.11 EEQ77524.1 - 8.5 5.6 14.2 12 5.1 9.9 1.2 1 0 0 1 1 1 0 Vta1 like STE PF02200.11 EEQ77525.1 - 8.1e-54 180.4 0.2 1.6e-53 179.5 0.1 1.5 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 EEQ77525.1 - 8.1e-11 41.6 14.5 1.3e-06 28.4 0.6 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ77525.1 - 8.4e-10 38.2 10.9 7.2e-05 22.8 1.0 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EEQ77525.1 - 3.1e-09 36.6 3.8 3.1e-09 36.6 2.6 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EEQ77525.1 - 0.0017 18.1 0.3 0.0052 16.6 0.0 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEQ77525.1 - 0.0058 16.7 1.5 0.16 12.1 0.0 3.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding Rtf2 PF04641.7 EEQ77525.1 - 0.0074 15.5 2.7 0.015 14.5 1.9 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger NOA36 PF06524.7 EEQ77525.1 - 0.0091 15.2 10.6 0.015 14.5 7.3 1.2 1 0 0 1 1 1 1 NOA36 protein zf-RING_3 PF14369.1 EEQ77525.1 - 0.096 12.6 0.3 0.23 11.4 0.2 1.6 1 0 0 1 1 1 0 zinc-finger zf-C2HC_2 PF13913.1 EEQ77525.1 - 0.099 12.3 5.2 0.11 12.1 0.3 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type FYDLN_acid PF09538.5 EEQ77525.1 - 0.099 13.2 1.9 0.28 11.7 1.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) MFS_2 PF13347.1 EEQ77526.1 - 0.00014 20.4 9.6 0.00021 19.8 2.4 2.9 2 1 0 2 2 2 1 MFS/sugar transport protein TFIIA PF03153.8 EEQ77526.1 - 0.006 16.5 0.0 0.0087 16.0 0.0 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF433 PF04255.9 EEQ77526.1 - 0.057 12.8 0.1 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF433) DUF3295 PF11702.3 EEQ77526.1 - 0.39 9.6 3.8 0.66 8.9 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Ebola_NP PF05505.7 EEQ77526.1 - 0.69 7.9 1.9 0.92 7.4 1.3 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein SDA1 PF05285.7 EEQ77526.1 - 0.95 8.6 4.3 1.5 8.0 3.0 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EEQ77526.1 - 2 6.2 4.6 2.7 5.7 3.2 1.1 1 0 0 1 1 1 0 Nop14-like family GATase PF00117.23 EEQ77527.1 - 6.7e-46 156.1 0.0 9.3e-46 155.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EEQ77527.1 - 9.2e-45 151.3 0.0 2.3e-44 150.0 0.0 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 EEQ77527.1 - 0.00025 20.5 0.3 0.0032 16.9 0.2 2.3 1 1 0 1 1 1 1 Peptidase C26 DUF1250 PF06855.7 EEQ77527.1 - 0.071 12.6 0.0 9.7 5.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1250) RNA_pol_I_A49 PF06870.7 EEQ77528.1 - 1.3e-48 165.5 0.0 3.2e-48 164.2 0.0 1.6 1 1 0 1 1 1 1 A49-like RNA polymerase I associated factor Aminotran_1_2 PF00155.16 EEQ77529.1 - 1.3e-82 277.6 0.0 1.6e-82 277.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EEQ77529.1 - 2.7e-06 25.9 0.0 4.3e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EEQ77529.1 - 5e-06 25.5 0.0 1.3e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EEQ77529.1 - 6.4e-05 22.1 0.2 0.00017 20.7 0.1 1.7 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EEQ77529.1 - 0.0035 16.5 0.2 0.05 12.7 0.2 2.4 2 1 0 2 2 2 1 Beta-eliminating lyase SNF2_N PF00176.18 EEQ77530.1 - 6.1e-71 238.6 3.6 1.8e-70 237.1 2.5 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 EEQ77530.1 - 1.8e-52 177.0 22.3 1.8e-52 177.0 15.5 4.6 3 1 1 4 4 4 1 DNA-binding domain Helicase_C PF00271.26 EEQ77530.1 - 4.9e-16 58.3 0.0 1.4e-15 56.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain p450 PF00067.17 EEQ77533.1 - 1.5e-39 135.8 0.0 2e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.7 EEQ77534.1 - 3e-29 100.9 1.7 5e-29 100.2 1.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ77534.1 - 9.1e-24 83.4 0.3 1.3e-23 82.9 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEQ77534.1 - 0.0003 21.6 0.1 0.00063 20.6 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EEQ77534.1 - 0.0032 16.6 0.1 0.0058 15.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EEQ77534.1 - 0.032 13.7 0.2 0.052 13.1 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Na_H_Exchanger PF00999.16 EEQ77535.1 - 2.4e-66 223.8 38.9 3.2e-66 223.4 27.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PepSY_TM_2 PF13703.1 EEQ77535.1 - 0.026 14.6 0.7 0.026 14.6 0.5 4.1 3 1 0 3 3 3 0 PepSY-associated TM helix F-box-like_2 PF13013.1 EEQ77536.1 - 0.038 13.7 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 F-box-like domain F-box-like PF12937.2 EEQ77536.1 - 0.15 11.8 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 F-box-like Peptidase_S10 PF00450.17 EEQ77537.1 - 2.2e-47 162.1 0.0 2.9e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase TPR_8 PF13181.1 EEQ77538.1 - 0.05 13.4 1.0 1.2 9.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat NIF PF03031.13 EEQ77539.1 - 2.2e-54 183.4 0.0 3.1e-54 182.9 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase MFS_1 PF07690.11 EEQ77540.1 - 7.1e-55 186.1 25.7 1e-54 185.5 17.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ77540.1 - 7.6e-13 47.8 6.4 7.6e-13 47.8 4.4 2.0 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 EEQ77540.1 - 2.2e-05 24.1 4.1 0.051 13.3 0.1 3.2 3 1 1 4 4 4 2 MFS_1 like family TRI12 PF06609.8 EEQ77540.1 - 0.00016 20.0 3.5 0.00025 19.4 2.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Methyltransf_10 PF05971.7 EEQ77540.1 - 0.018 14.1 0.1 0.071 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF890) p450 PF00067.17 EEQ77541.1 - 9.9e-52 175.9 0.0 1.3e-51 175.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DIT1_PvcA PF05141.7 EEQ77542.1 - 7.5e-88 294.4 0.0 1e-87 293.9 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein IF-2B PF01008.12 EEQ77543.1 - 9.9e-62 208.4 1.2 3.9e-59 199.9 0.8 3.1 1 1 0 1 1 1 1 Initiation factor 2 subunit family 3HCDH_N PF02737.13 EEQ77543.1 - 0.055 13.1 0.1 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosom_S12_S23 PF00164.20 EEQ77544.1 - 7.8e-41 138.3 0.4 9e-41 138.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_L17 PF01196.14 EEQ77547.1 - 1.5e-30 105.5 0.0 2.7e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 Mn_catalase PF05067.7 EEQ77547.1 - 0.024 13.3 0.1 0.036 12.8 0.1 1.2 1 0 0 1 1 1 0 Manganese containing catalase DUF1192 PF06698.6 EEQ77547.1 - 6.2 6.7 7.4 1.4 8.7 1.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) PNRC PF15365.1 EEQ77548.1 - 0.045 13.7 0.3 0.15 12.1 0.2 1.9 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator SUZ PF12752.2 EEQ77549.1 - 2.6e-21 75.8 3.8 2.6e-21 75.8 2.6 3.4 4 0 0 4 4 4 1 SUZ domain R3H PF01424.17 EEQ77549.1 - 2.3e-09 36.8 0.1 8e-09 35.0 0.0 1.9 2 0 0 2 2 2 1 R3H domain zf-CCHC_3 PF13917.1 EEQ77550.1 - 2.9e-09 36.5 2.5 1.3e-08 34.4 1.8 2.2 1 1 0 1 1 1 1 Zinc knuckle cwf18 PF08315.7 EEQ77551.1 - 1.5e-43 148.3 5.6 1.5e-43 148.3 3.9 1.7 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor PPR_2 PF13041.1 EEQ77552.1 - 5.1e-14 51.9 1.2 0.00018 21.4 0.0 4.6 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.1 EEQ77552.1 - 3.4e-10 39.3 1.9 0.015 15.5 0.0 6.7 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR PF01535.15 EEQ77552.1 - 0.0026 17.5 0.4 3.8 7.6 0.0 4.4 4 0 0 4 4 4 1 PPR repeat PPR_1 PF12854.2 EEQ77552.1 - 0.0068 15.8 0.3 31 4.1 0.0 4.1 4 0 0 4 4 4 2 PPR repeat DUF1242 PF06842.7 EEQ77553.1 - 1.9e-19 68.8 0.9 2.3e-19 68.5 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1242) PAGK PF15284.1 EEQ77553.1 - 0.028 14.1 0.1 0.06 13.1 0.0 1.6 2 0 0 2 2 2 0 Phage-encoded virulence factor TFIID-18kDa PF02269.11 EEQ77554.1 - 7.7e-21 73.7 0.1 1.5e-20 72.7 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 EEQ77554.1 - 0.00031 20.7 0.2 0.0008 19.4 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EEQ77554.1 - 0.013 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) TFIID_20kDa PF03847.8 EEQ77554.1 - 0.062 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Orbi_VP6 PF01516.11 EEQ77554.1 - 1 8.3 10.0 1.6 7.7 6.9 1.3 1 0 0 1 1 1 0 Orbivirus helicase VP6 JAB PF01398.16 EEQ77555.1 - 2.4e-17 62.7 0.0 3.8e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EEQ77555.1 - 1.5e-15 57.2 0.0 2.7e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.8 EEQ77555.1 - 0.033 13.6 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF1253 PF06862.7 EEQ77556.1 - 1.6e-169 564.0 0.0 1.9e-169 563.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DEAD PF00270.24 EEQ77556.1 - 0.006 16.0 0.1 0.44 10.0 0.1 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF2895 PF11444.3 EEQ77556.1 - 0.14 11.3 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) EamA PF00892.15 EEQ77557.1 - 1.1e-13 51.2 21.1 2.5e-08 34.0 3.7 2.3 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EEQ77557.1 - 0.0013 18.8 22.3 0.015 15.4 2.0 3.3 3 1 1 4 4 4 2 Multidrug resistance efflux transporter DUF3357 PF11837.3 EEQ77557.1 - 0.025 14.3 2.9 2 8.3 0.0 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF3357) RNA_pol_3_Rpc31 PF11705.3 EEQ77557.1 - 3.7 7.4 13.7 8.1 6.3 9.5 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CTP_transf_2 PF01467.21 EEQ77558.1 - 1.6e-05 25.0 0.0 3.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase PP2C PF00481.16 EEQ77559.1 - 1.2e-75 254.2 0.1 1.8e-75 253.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EEQ77559.1 - 0.00019 20.9 0.0 0.00045 19.6 0.0 1.7 1 0 0 1 1 1 1 Protein phosphatase 2C RTC4 PF14474.1 EEQ77565.1 - 2.5e-27 95.2 0.1 4e-27 94.6 0.1 1.3 1 0 0 1 1 1 1 RTC4-like domain Myb_DNA-bind_6 PF13921.1 EEQ77565.1 - 0.014 15.5 3.3 0.021 14.9 1.4 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain Pkinase PF00069.20 EEQ77566.1 - 1.9e-30 105.9 0.0 1e-29 103.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ77566.1 - 9.2e-10 38.0 0.0 5.5e-07 28.9 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 EEQ77566.1 - 0.00026 20.0 0.0 0.017 14.1 0.0 2.6 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EEQ77566.1 - 0.0051 16.5 0.1 0.14 11.8 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF3796 PF12676.2 EEQ77567.1 - 0.49 10.6 2.5 0.56 10.4 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) TPPK_C PF12555.3 EEQ77567.1 - 1.1 9.0 8.3 1.5 8.6 5.8 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal CbiA PF01656.18 EEQ77567.1 - 2.1 7.6 6.9 14 5.0 4.8 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF3716 PF12511.3 EEQ77568.1 - 0.056 13.0 0.8 0.087 12.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) DUF2284 PF10050.4 EEQ77568.1 - 0.083 12.4 0.3 0.1 12.1 0.2 1.1 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) EST1 PF10374.4 EEQ77574.1 - 0.047 13.6 3.8 0.059 13.3 2.6 1.1 1 0 0 1 1 1 0 Telomerase activating protein Est1 RyR PF02026.11 EEQ77574.1 - 0.065 13.2 1.3 0.15 12.1 0.7 1.8 1 1 0 1 1 1 0 RyR domain DUF3723 PF12520.3 EEQ77575.1 - 3e-27 95.2 0.6 3e-27 95.2 0.4 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3723) AAA_23 PF13476.1 EEQ77575.1 - 0.018 15.3 2.9 0.035 14.4 2.0 1.5 1 0 0 1 1 1 0 AAA domain DUF4291 PF14124.1 EEQ77576.1 - 0.035 13.7 0.5 0.048 13.2 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4291) Histone PF00125.19 EEQ77577.1 - 0.00052 20.0 0.1 0.00068 19.7 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Acetyltransf_1 PF00583.19 EEQ77578.1 - 3.7e-09 36.5 0.1 8.2e-09 35.3 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ77578.1 - 5.1e-07 29.7 0.1 7.7e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEQ77578.1 - 3.9e-06 26.9 0.1 7.7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEQ77578.1 - 0.0019 18.0 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EEQ77578.1 - 0.036 13.8 0.0 0.1 12.3 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein DUF3749 PF12568.3 EEQ77578.1 - 0.04 13.5 0.1 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZART1 PF12554.3 EEQ77579.1 - 9.2e-18 63.4 1.4 9.2e-18 63.4 1.0 1.7 2 0 0 2 2 2 1 Mitotic-spindle organizing gamma-tubulin ring associated dUTPase_2 PF08761.6 EEQ77579.1 - 0.13 12.2 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 dUTPase DUF3067 PF11267.3 EEQ77579.1 - 0.17 11.9 0.3 0.37 10.8 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3067) CUE PF02845.11 EEQ77580.1 - 4.3e-11 42.0 0.0 6.9e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 CUE domain OB_NTP_bind PF07717.11 EEQ77581.1 - 1.3e-22 79.8 0.0 2.2e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EEQ77581.1 - 1.2e-18 67.0 0.0 2.2e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEQ77581.1 - 2.5e-13 49.6 0.0 5e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EEQ77581.1 - 4.1e-05 23.7 0.0 0.0001 22.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EEQ77581.1 - 0.00058 19.3 0.1 0.0023 17.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase cobW PF02492.14 EEQ77581.1 - 0.0085 15.5 0.0 0.13 11.7 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EEQ77581.1 - 0.0094 15.5 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EEQ77581.1 - 0.011 14.6 0.1 0.026 13.4 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 EEQ77581.1 - 0.033 13.3 0.4 0.15 11.1 0.1 2.1 1 1 1 2 2 2 0 Zeta toxin AAA_14 PF13173.1 EEQ77581.1 - 0.042 13.7 0.0 10 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 EEQ77581.1 - 0.078 11.5 0.0 0.15 10.6 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Herpes_ori_bp PF02399.10 EEQ77581.1 - 0.11 10.3 0.0 0.17 9.8 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein AAA_23 PF13476.1 EEQ77581.1 - 0.17 12.1 0.0 0.41 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain PITH PF06201.8 EEQ77582.1 - 1.3e-46 158.0 0.0 1.6e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 PITH domain BofC_C PF08955.5 EEQ77582.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 BofC C-terminal domain Snf7 PF03357.16 EEQ77583.1 - 7.5e-33 113.3 5.1 7.5e-33 113.3 3.5 1.8 2 0 0 2 2 2 1 Snf7 Silic_transp PF03842.8 EEQ77583.1 - 0.091 10.8 0.7 0.13 10.3 0.5 1.2 1 0 0 1 1 1 0 Silicon transporter Nsp1_C PF05064.8 EEQ77583.1 - 0.099 12.2 0.2 0.099 12.2 0.1 2.3 3 0 0 3 3 3 0 Nsp1-like C-terminal region AAA PF00004.24 EEQ77584.1 - 2.1e-89 296.5 0.0 4.3e-44 149.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EEQ77584.1 - 6.6e-14 51.5 0.0 9e-07 28.1 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EEQ77584.1 - 2.2e-13 50.6 0.4 1.7e-05 24.9 0.0 3.8 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EEQ77584.1 - 5.8e-13 49.1 0.2 0.0035 17.4 0.0 5.3 2 2 1 3 3 3 2 AAA domain AAA_5 PF07728.9 EEQ77584.1 - 3e-11 43.2 0.2 0.00079 19.1 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EEQ77584.1 - 3.7e-11 43.2 0.0 5.6e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EEQ77584.1 - 1.3e-10 42.1 0.0 1.9e-05 25.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EEQ77584.1 - 2.3e-10 40.4 0.0 0.00016 21.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.1 EEQ77584.1 - 1.2e-09 38.1 0.0 0.00058 19.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EEQ77584.1 - 2.1e-09 36.7 0.0 0.0019 17.3 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 EEQ77584.1 - 5.9e-09 35.1 0.0 8.6e-05 21.4 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 EEQ77584.1 - 1.9e-08 33.9 0.3 0.0088 15.7 0.0 3.6 3 0 0 3 3 3 2 Part of AAA domain RNA_helicase PF00910.17 EEQ77584.1 - 5.7e-08 32.8 0.0 0.0044 17.1 0.0 2.7 2 1 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 EEQ77584.1 - 1.7e-07 31.3 0.0 0.0046 16.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EEQ77584.1 - 1.8e-07 30.7 0.4 0.02 14.3 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 EEQ77584.1 - 3.4e-07 29.6 0.3 0.019 14.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EEQ77584.1 - 3.7e-07 30.5 0.1 0.005 17.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_3 PF07726.6 EEQ77584.1 - 9.2e-07 28.5 0.0 0.0033 17.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EEQ77584.1 - 1.1e-06 28.3 0.4 0.12 11.9 0.0 4.0 3 1 0 4 4 4 2 NACHT domain AAA_25 PF13481.1 EEQ77584.1 - 3.7e-06 26.4 4.3 1.2 8.4 0.1 4.4 2 2 2 4 4 4 3 AAA domain KaiC PF06745.8 EEQ77584.1 - 3.2e-05 23.1 0.1 0.61 9.1 0.0 3.3 2 1 1 3 3 3 2 KaiC Cytidylate_kin2 PF13189.1 EEQ77584.1 - 3.3e-05 23.8 0.0 0.0041 17.0 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family Sigma54_activ_2 PF14532.1 EEQ77584.1 - 5.4e-05 23.2 0.0 0.41 10.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 EEQ77584.1 - 6.3e-05 23.2 0.0 0.41 10.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter Sigma54_activat PF00158.21 EEQ77584.1 - 8.6e-05 22.0 0.0 0.29 10.6 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 EEQ77584.1 - 0.00012 21.3 0.0 0.26 10.5 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein SKI PF01202.17 EEQ77584.1 - 0.00014 21.8 0.0 0.45 10.3 0.0 2.6 2 0 0 2 2 2 2 Shikimate kinase Arch_ATPase PF01637.13 EEQ77584.1 - 0.00021 21.0 0.0 1.8 8.1 0.0 3.7 2 2 1 3 3 3 1 Archaeal ATPase NB-ARC PF00931.17 EEQ77584.1 - 0.00042 19.2 0.1 0.3 9.9 0.0 2.6 3 0 0 3 3 3 1 NB-ARC domain AFG1_ATPase PF03969.11 EEQ77584.1 - 0.00044 19.1 0.1 0.14 10.8 0.0 2.7 2 1 0 2 2 2 1 AFG1-like ATPase ResIII PF04851.10 EEQ77584.1 - 0.00074 19.3 0.0 1.7 8.4 0.0 2.8 2 1 1 3 3 2 1 Type III restriction enzyme, res subunit Rad17 PF03215.10 EEQ77584.1 - 0.00081 18.1 0.0 0.38 9.3 0.0 2.4 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein Parvo_NS1 PF01057.12 EEQ77584.1 - 0.00086 18.2 0.0 1.2 7.9 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.8 EEQ77584.1 - 0.0016 17.4 0.0 0.051 12.4 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_11 PF13086.1 EEQ77584.1 - 0.002 17.7 0.0 0.81 9.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EEQ77584.1 - 0.002 17.6 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 EEQ77584.1 - 0.003 17.1 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 EEQ77584.1 - 0.0079 15.9 0.1 2.2 7.9 0.0 3.1 2 1 1 3 3 3 1 NTPase ATP-synt_ab PF00006.20 EEQ77584.1 - 0.011 15.2 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 EEQ77584.1 - 0.014 14.9 0.1 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 EEQ77584.1 - 0.016 14.8 0.0 0.37 10.3 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF2075 PF09848.4 EEQ77584.1 - 0.041 12.8 0.0 3.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.1 EEQ77584.1 - 0.067 13.5 0.1 3.2 8.0 0.0 2.9 4 0 0 4 4 2 0 AAA domain IPT PF01745.11 EEQ77584.1 - 0.072 12.2 0.1 6.7 5.8 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase KTI12 PF08433.5 EEQ77584.1 - 0.1 11.7 0.0 23 4.0 0.0 3.2 3 0 0 3 3 3 0 Chromatin associated protein KTI12 BOP1NT PF08145.7 EEQ77585.1 - 4.7e-104 347.7 5.1 6.8e-104 347.1 3.5 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EEQ77585.1 - 1.6e-23 81.6 11.1 2.6e-09 36.6 0.3 6.6 7 1 0 7 7 7 4 WD domain, G-beta repeat Zn_clus PF00172.13 EEQ77586.1 - 6.9e-10 38.6 6.8 1.4e-09 37.6 4.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Leo1 PF04004.8 EEQ77588.1 - 1e-33 116.4 0.0 2.3e-33 115.3 0.0 1.6 1 0 0 1 1 1 1 Leo1-like protein Mob1_phocein PF03637.12 EEQ77589.1 - 2.8e-29 102.0 2.6 4.5e-14 52.4 1.1 2.3 2 0 0 2 2 2 2 Mob1/phocein family ATG16 PF08614.6 EEQ77590.1 - 0.019 14.7 0.1 0.019 14.7 0.1 1.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Sigma54_AID PF00309.15 EEQ77590.1 - 0.034 13.6 0.1 0.078 12.4 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) Rhomboid PF01694.17 EEQ77591.1 - 2e-25 89.5 7.2 2e-25 89.5 5.0 1.7 2 0 0 2 2 2 1 Rhomboid family PhoD PF09423.5 EEQ77592.1 - 2e-09 36.5 0.4 1.1e-06 27.5 0.1 2.6 2 1 0 2 2 2 2 PhoD-like phosphatase LepA_C PF06421.7 EEQ77592.1 - 0.15 11.9 0.1 0.76 9.7 0.0 2.1 2 0 0 2 2 2 0 GTP-binding protein LepA C-terminus Cyt-b5 PF00173.23 EEQ77593.1 - 4.7e-13 48.7 0.0 1.1e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 EEQ77593.1 - 0.02 14.3 2.8 0.04 13.3 1.9 1.5 1 0 0 1 1 1 0 Fatty acid desaturase BRCA-2_helical PF09169.5 EEQ77593.1 - 0.055 13.0 0.1 0.43 10.1 0.0 2.0 2 0 0 2 2 2 0 BRCA2, helical Gryzun PF07919.7 EEQ77594.1 - 5.2e-144 480.5 0.3 7e-144 480.1 0.2 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 EEQ77594.1 - 6.2e-101 337.0 1.0 2e-89 299.3 2.3 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.2 EEQ77594.1 - 0.041 13.6 0.0 0.093 12.5 0.0 1.6 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Reprolysin_4 PF13583.1 EEQ77594.1 - 0.17 11.3 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Abhydrolase_6 PF12697.2 EEQ77596.1 - 1.5e-18 67.5 0.4 6.2e-18 65.5 0.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ77596.1 - 3.6e-08 33.2 0.0 1.9e-06 27.6 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ77596.1 - 3.7e-05 23.3 0.0 7.4e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DivIC PF04977.10 EEQ77596.1 - 2.3 7.7 4.1 4.7 6.7 2.9 1.4 1 0 0 1 1 1 0 Septum formation initiator RTA1 PF04479.8 EEQ77597.1 - 4.8e-33 114.5 0.1 8e-33 113.8 0.1 1.3 1 0 0 1 1 1 1 RTA1 like protein WAP PF00095.16 EEQ77600.1 - 0.3 11.0 3.4 0.51 10.3 2.4 1.5 1 0 0 1 1 1 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Glutaredoxin PF00462.19 EEQ77602.1 - 6.1e-14 51.7 0.0 1.4e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin Ribosomal_L6 PF00347.18 EEQ77603.1 - 4.2e-23 81.6 5.8 1.3e-11 44.8 0.8 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 DUF3336 PF11815.3 EEQ77604.1 - 4.3e-29 100.8 0.1 6.6e-29 100.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EEQ77604.1 - 3.4e-11 43.4 1.6 1.5e-10 41.3 1.1 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase RXT2_N PF08595.6 EEQ77605.1 - 1.3e-41 141.8 0.6 1.3e-41 141.8 0.4 2.7 2 1 0 2 2 2 1 RXT2-like, N-terminal PEMT PF04191.8 EEQ77606.1 - 6.3e-32 109.8 5.2 1.3e-31 108.8 1.7 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1223 PF06764.6 EEQ77606.1 - 0.046 13.5 0.0 0.064 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) PXA PF02194.10 EEQ77607.1 - 4.4e-52 176.3 0.1 4.4e-52 176.3 0.1 2.5 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 EEQ77607.1 - 4.2e-23 81.5 0.6 4.7e-22 78.2 0.0 2.6 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 EEQ77607.1 - 9.5e-21 73.7 0.6 2.3e-20 72.4 0.4 1.7 1 0 0 1 1 1 1 PX domain RGS PF00615.14 EEQ77607.1 - 4.4e-09 36.4 0.0 1.3e-08 34.9 0.0 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF4622 PF15415.1 EEQ77607.1 - 0.077 11.7 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4622) LRR19-TM PF15176.1 EEQ77607.1 - 0.089 12.4 1.1 0.36 10.5 0.1 2.5 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain NB-ARC PF00931.17 EEQ77608.1 - 0.13 11.1 0.1 0.55 9.0 0.1 1.9 1 1 0 1 1 1 0 NB-ARC domain WD40 PF00400.27 EEQ77611.1 - 8.9e-28 95.1 5.8 1.1e-08 34.5 0.1 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat tRNA-synt_1g PF09334.6 EEQ77612.1 - 9.1e-135 449.2 0.0 1.2e-134 448.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EEQ77612.1 - 1.5e-05 23.1 0.1 0.12 10.3 0.0 3.7 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EEQ77612.1 - 0.0093 15.7 0.1 0.02 14.6 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Elongin_A PF06881.6 EEQ77612.1 - 0.16 12.3 7.7 0.23 11.8 3.7 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A OppC_N PF12911.2 EEQ77612.1 - 0.17 11.2 1.0 0.46 9.8 0.7 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Yae1_N PF09811.4 EEQ77613.1 - 3.2e-08 32.9 3.9 5e-08 32.3 2.7 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal FSIP1 PF15554.1 EEQ77613.1 - 0.041 12.6 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 FSIP1 family UPF0160 PF03690.8 EEQ77614.1 - 8.8e-114 380.1 0.0 1e-113 380.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) ICE2 PF08426.5 EEQ77615.1 - 3.2e-150 500.3 6.6 3.7e-150 500.1 4.6 1.0 1 0 0 1 1 1 1 ICE2 Endosulfine PF04667.12 EEQ77616.1 - 3.3e-22 78.2 0.0 7.7e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region RNA_Me_trans PF04252.8 EEQ77617.1 - 7e-47 159.3 0.0 7.9e-47 159.1 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Peptidase_S10 PF00450.17 EEQ77618.1 - 1.8e-110 369.9 0.0 2.4e-110 369.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EEQ77618.1 - 0.0025 17.7 0.0 0.01 15.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Herpes_gE PF02480.11 EEQ77618.1 - 0.077 11.2 0.0 0.11 10.6 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E WD40 PF00400.27 EEQ77619.1 - 5e-54 178.3 21.1 8.8e-10 38.0 0.2 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EEQ77619.1 - 7.5e-05 22.1 0.0 0.13 11.8 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 EEQ77619.1 - 0.096 10.4 0.8 0.3 8.8 0.2 1.9 2 0 0 2 2 2 0 IKI3 family Tcp11 PF05794.8 EEQ77620.1 - 1.9e-52 178.5 1.6 1.9e-51 175.1 0.0 2.6 2 1 0 2 2 2 1 T-complex protein 11 DUF1446 PF07287.6 EEQ77621.1 - 3.2e-132 440.3 0.1 3.9e-132 440.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) MUG113 PF13455.1 EEQ77622.1 - 6.8e-13 48.8 0.8 2.1e-12 47.2 0.5 1.9 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EEQ77622.1 - 2.4e-09 37.4 0.8 6.9e-09 36.0 0.5 1.8 1 0 0 1 1 1 1 T5orf172 domain ArfGap PF01412.13 EEQ77622.1 - 0.12 12.1 0.7 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Transket_pyr PF02779.19 EEQ77623.1 - 2.4e-41 141.1 0.0 3.7e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EEQ77623.1 - 3.3e-31 107.7 0.0 6.9e-31 106.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain XPG_N PF00752.12 EEQ77624.1 - 1e-34 118.8 0.0 2.5e-34 117.5 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EEQ77624.1 - 1.1e-24 86.2 0.0 3.1e-24 84.8 0.0 1.9 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EEQ77624.1 - 0.00074 19.7 0.0 0.0023 18.1 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold UIM PF02809.15 EEQ77624.1 - 0.024 14.1 0.1 0.024 14.1 0.1 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif Transposase_20 PF02371.11 EEQ77624.1 - 0.025 14.6 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family HHH_5 PF14520.1 EEQ77624.1 - 0.034 14.3 0.0 0.083 13.0 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain DHFR_1 PF00186.14 EEQ77624.1 - 0.12 11.9 0.3 9.3 5.8 0.0 3.3 4 0 0 4 4 4 0 Dihydrofolate reductase adh_short PF00106.20 EEQ77625.1 - 9.7e-22 77.6 0.0 2.1e-21 76.5 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ77625.1 - 7.6e-11 42.2 0.0 9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ77625.1 - 1.2e-06 28.3 0.0 2.6e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EEQ77625.1 - 0.12 11.2 0.0 2.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Abhydrolase_1 PF00561.15 EEQ77627.1 - 1.2e-43 149.3 0.0 1.6e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEQ77627.1 - 2.2e-14 53.9 0.3 1.3e-13 51.3 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ77627.1 - 0.00035 20.3 0.0 0.25 11.0 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EEQ77627.1 - 0.026 14.4 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein DUF2424 PF10340.4 EEQ77627.1 - 0.16 10.5 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) EXS PF03124.9 EEQ77628.1 - 3.1e-81 273.0 20.7 5.9e-72 242.5 10.8 2.1 1 1 1 2 2 2 2 EXS family SPX PF03105.14 EEQ77628.1 - 1.2e-63 215.4 0.6 1.2e-63 215.4 0.4 2.0 2 0 0 2 2 2 1 SPX domain Semialdhyde_dhC PF02774.13 EEQ77630.1 - 1.6e-37 129.1 0.0 2.2e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EEQ77630.1 - 3.4e-28 98.3 0.0 9.2e-28 96.9 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EEQ77630.1 - 0.0035 17.8 0.0 0.0065 16.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 EEQ77630.1 - 0.02 14.7 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Baculo_PEP_C PF04513.7 EEQ77631.1 - 0.17 11.7 1.0 1.3 8.8 0.1 2.4 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Acyl-CoA_dh_N PF02771.11 EEQ77633.1 - 5e-27 94.7 0.0 1.5e-26 93.2 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EEQ77633.1 - 6.7e-25 87.9 0.2 1e-24 87.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EEQ77633.1 - 7.5e-16 57.3 0.0 2e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EEQ77633.1 - 8e-08 32.6 0.3 1.5e-07 31.7 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pectate_lyase_3 PF12708.2 EEQ77635.1 - 4.9e-62 209.9 9.3 1.1e-52 179.3 2.8 2.8 2 0 0 2 2 2 2 Pectate lyase superfamily protein BNR_assoc_N PF14873.1 EEQ77635.1 - 0.009 15.7 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of BNR-repeat neuraminidase Peptidase_S8 PF00082.17 EEQ77636.1 - 5.1e-13 48.7 0.0 1.1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Subtilase family PagP PF07017.6 EEQ77636.1 - 0.015 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Antimicrobial peptide resistance and lipid A acylation protein PagP p450 PF00067.17 EEQ77637.1 - 1.6e-67 228.0 0.0 2.1e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EEQ77638.1 - 1.9e-54 184.9 0.0 2.3e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AA_permease PF00324.16 EEQ77639.1 - 1.2e-138 462.4 51.0 1.4e-138 462.2 35.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ77639.1 - 1.5e-37 129.1 54.8 2.3e-37 128.5 37.8 1.3 1 1 0 1 1 1 1 Amino acid permease Pro_isomerase PF00160.16 EEQ77642.1 - 8.8e-51 172.1 0.1 1.7e-50 171.2 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EEQ77642.1 - 2.6e-10 39.7 4.9 0.02 14.7 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Cpn60_TCP1 PF00118.19 EEQ77643.1 - 3.5e-135 451.3 9.9 4.3e-135 451.0 6.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CO_deh_flav_C PF03450.12 EEQ77643.1 - 0.41 10.6 3.0 1.6 8.6 0.2 2.8 2 0 0 2 2 2 0 CO dehydrogenase flavoprotein C-terminal domain Pkinase PF00069.20 EEQ77644.1 - 1.8e-41 141.9 0.0 3.3e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 EEQ77644.1 - 9.2e-41 138.7 0.0 1.6e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 EEQ77644.1 - 3.7e-20 72.0 0.0 1.5e-19 70.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 EEQ77644.1 - 0.00071 18.9 0.1 0.078 12.5 0.0 2.9 2 0 0 2 2 2 1 PQQ enzyme repeat Kdo PF06293.9 EEQ77644.1 - 0.077 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_2 PF13360.1 EEQ77644.1 - 0.086 12.2 0.1 0.45 9.9 0.0 2.0 1 1 1 2 2 2 0 PQQ-like domain Cytokin_check_N PF10407.4 EEQ77645.1 - 0.032 13.8 0.0 0.076 12.6 0.0 1.6 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus DUF1090 PF06476.7 EEQ77645.1 - 0.16 11.6 2.2 0.35 10.5 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) CHD5 PF04420.9 EEQ77645.1 - 8.1 6.0 4.8 29 4.2 0.3 2.3 2 0 0 2 2 2 0 CHD5-like protein Aminotran_4 PF01063.14 EEQ77646.1 - 2.8e-20 72.7 0.0 3.4e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Abhydrolase_1 PF00561.15 EEQ77647.1 - 4.7e-14 52.4 0.0 1.6e-13 50.7 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEQ77647.1 - 6.5e-11 42.5 0.0 1.2e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ77647.1 - 0.04 13.6 0.0 0.31 10.8 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.15 EEQ77647.1 - 0.064 12.6 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase adh_short PF00106.20 EEQ77648.1 - 2.6e-22 79.4 0.0 4.4e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ77648.1 - 8.3e-14 51.9 0.0 1.1e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ77648.1 - 2.4e-06 27.3 0.0 3.7e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EEQ77648.1 - 4.1e-05 23.6 0.1 6.1e-05 23.1 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEQ77648.1 - 0.0016 17.9 0.0 0.0029 17.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EEQ77648.1 - 0.029 14.1 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase F420_oxidored PF03807.12 EEQ77648.1 - 0.031 14.7 0.0 0.073 13.5 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 EEQ77648.1 - 0.068 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Thioesterase PF00975.15 EEQ77649.1 - 1e-12 48.7 0.0 5.9e-10 39.7 0.0 2.2 2 1 0 2 2 2 2 Thioesterase domain Abhydrolase_6 PF12697.2 EEQ77649.1 - 0.00069 19.5 0.1 0.0011 18.9 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ77649.1 - 0.0018 18.0 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EEQ77649.1 - 0.022 14.3 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EEQ77649.1 - 0.14 11.5 0.1 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase MFS_1 PF07690.11 EEQ77652.1 - 6.6e-32 110.5 26.2 9.4e-32 110.0 18.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily RRM_1 PF00076.17 EEQ77653.1 - 0.16 11.6 0.0 13 5.4 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pam17 PF08566.5 EEQ77654.1 - 1.1e-70 236.8 0.0 1.8e-70 236.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DUF599 PF04654.7 EEQ77654.1 - 0.093 11.8 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF599 Far-17a_AIG1 PF04750.9 EEQ77655.1 - 1.1e-66 223.8 11.7 1.3e-66 223.6 8.1 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF3177 PF11375.3 EEQ77655.1 - 0.007 15.8 0.8 0.016 14.6 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3177) TMEM213 PF15192.1 EEQ77655.1 - 0.13 12.2 0.1 0.37 10.8 0.1 1.7 1 1 0 1 1 1 0 TMEM213 family Tetraspannin PF00335.15 EEQ77655.1 - 3.8 6.7 6.5 3.8 6.7 0.9 2.0 2 0 0 2 2 2 0 Tetraspanin family DUF3602 PF12223.3 EEQ77656.1 - 1.9e-11 44.1 7.7 7e-10 39.1 1.2 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) Velvet PF11754.3 EEQ77657.1 - 6.9e-64 215.1 0.0 5.8e-56 189.3 0.0 2.1 1 1 1 2 2 2 2 Velvet factor APH PF01636.18 EEQ77658.1 - 9.3e-07 28.8 0.0 5.8e-06 26.2 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ77658.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase TPR_2 PF07719.12 EEQ77660.1 - 0.00099 18.8 0.0 1.1 9.3 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ77660.1 - 0.0022 17.6 0.0 0.64 9.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat BCS1_N PF08740.6 EEQ77661.1 - 2.8e-29 102.0 0.0 4.1e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal IncA PF04156.9 EEQ77662.1 - 0.03 13.9 2.5 0.04 13.5 1.8 1.1 1 0 0 1 1 1 0 IncA protein Phage_lysis PF03245.8 EEQ77662.1 - 0.06 13.3 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein ADIP PF11559.3 EEQ77662.1 - 0.15 11.9 3.8 0.26 11.1 2.4 1.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Lge1 PF11488.3 EEQ77662.1 - 0.58 10.3 2.5 3.9 7.7 0.7 2.3 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 Pkinase PF00069.20 EEQ77663.1 - 1.6e-33 115.9 0.0 2.1e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ77663.1 - 1.1e-12 47.5 0.0 1e-11 44.4 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase NACHT PF05729.7 EEQ77666.1 - 7.9e-15 54.9 0.0 1.3e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.9 EEQ77666.1 - 7.5e-05 22.1 0.0 0.00017 20.9 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EEQ77666.1 - 0.00032 20.3 0.0 0.00061 19.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EEQ77666.1 - 0.0022 17.7 0.0 0.0035 17.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_22 PF13401.1 EEQ77666.1 - 0.0046 17.0 0.0 0.037 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEQ77666.1 - 0.0092 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_35 PF14516.1 EEQ77666.1 - 0.018 13.6 0.1 0.35 9.4 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain Abhydrolase_6 PF12697.2 EEQ77666.1 - 0.021 14.7 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_19 PF13245.1 EEQ77666.1 - 0.038 13.7 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 EEQ77666.1 - 0.053 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.1 EEQ77666.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EEQ77666.1 - 0.14 12.3 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Spt4 PF06093.8 EEQ77666.1 - 0.16 11.9 0.0 1.1 9.1 0.0 2.3 3 0 0 3 3 3 0 Spt4/RpoE2 zinc finger Kelch_4 PF13418.1 EEQ77666.1 - 2.2 8.1 5.7 13 5.6 0.1 3.4 3 1 0 3 3 3 0 Galactose oxidase, central domain MFS_1 PF07690.11 EEQ77667.1 - 2.2e-23 82.5 17.1 2.7e-23 82.2 11.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ77667.1 - 7.7e-11 41.2 3.6 1.1e-10 40.7 2.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EEQ77667.1 - 0.13 10.5 5.7 0.064 11.6 2.3 1.5 1 1 0 1 1 1 0 MFS/sugar transport protein DOCK-C2 PF14429.1 EEQ77669.1 - 0.074 12.6 0.9 0.085 12.4 0.1 1.4 2 0 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins Ribonuc_L-PSP PF01042.16 EEQ77670.1 - 5.1e-40 135.9 0.1 5.8e-40 135.8 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP CopD PF05425.8 EEQ77672.1 - 0.17 12.1 3.1 0.38 10.9 0.1 2.4 2 0 0 2 2 2 0 Copper resistance protein D Glyco_hydro_47 PF01532.15 EEQ77673.1 - 8.1e-134 446.6 0.0 1e-133 446.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 V-ATPase_G PF03179.10 EEQ77677.1 - 4.3e-33 113.7 18.8 5e-33 113.5 13.1 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 EEQ77677.1 - 0.0014 18.4 11.0 0.0014 18.4 7.6 2.1 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) DUF3552 PF12072.3 EEQ77677.1 - 0.014 14.5 12.6 0.014 14.5 8.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) HypD PF01924.11 EEQ77677.1 - 0.17 10.6 2.8 0.2 10.3 1.9 1.1 1 0 0 1 1 1 0 Hydrogenase formation hypA family Nop25 PF09805.4 EEQ77677.1 - 0.18 11.9 15.5 0.21 11.6 10.8 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) EURL PF06937.6 EEQ77677.1 - 0.31 10.4 6.1 0.35 10.2 4.2 1.1 1 0 0 1 1 1 0 EURL protein RRF PF01765.14 EEQ77677.1 - 0.31 10.4 11.2 0.46 9.9 7.7 1.3 1 0 0 1 1 1 0 Ribosome recycling factor DUF2870 PF11069.3 EEQ77677.1 - 0.55 10.2 6.6 0.79 9.7 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) RGS-like PF09128.6 EEQ77677.1 - 0.56 9.6 7.5 0.72 9.3 5.2 1.3 1 1 0 1 1 1 0 Regulator of G protein signalling-like domain OmpH PF03938.9 EEQ77677.1 - 0.59 10.0 15.7 0.69 9.8 10.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Toxin_43 PF15604.1 EEQ77677.1 - 1.1 9.2 11.1 1.6 8.7 7.7 1.2 1 0 0 1 1 1 0 Putative toxin 43 Vfa1 PF08432.5 EEQ77677.1 - 1.2 9.1 11.2 1.4 8.9 7.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 MMR_HSR1_C PF08438.5 EEQ77677.1 - 1.6 9.0 5.4 2.2 8.5 3.6 1.3 1 1 0 1 1 1 0 GTPase of unknown function C-terminal DUF2151 PF10221.4 EEQ77677.1 - 2.5 6.1 7.8 2.8 5.9 5.4 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Endonuc_Holl PF10107.4 EEQ77677.1 - 4.2 7.0 9.1 7 6.3 6.3 1.4 1 1 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF4168 PF13767.1 EEQ77677.1 - 4.6 7.9 10.7 1.2 9.7 4.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4168) Hom_end_hint PF05203.11 EEQ77677.1 - 4.7 6.8 6.7 5.5 6.6 4.6 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint APG6 PF04111.7 EEQ77677.1 - 6.2 5.7 11.0 6.9 5.6 7.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 GAS PF13851.1 EEQ77679.1 - 0.19 10.9 23.2 0.021 13.9 11.4 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DivIVA PF05103.8 EEQ77679.1 - 1 9.3 25.0 0.49 10.4 0.1 3.2 2 1 0 2 2 2 0 DivIVA protein Methyltransf_16 PF10294.4 EEQ77680.1 - 6.3e-18 64.8 0.0 9.4e-18 64.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EEQ77680.1 - 1.1e-06 29.1 0.0 2.3e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EEQ77680.1 - 3.4e-05 23.0 0.0 5.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 EEQ77680.1 - 0.0012 18.1 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EEQ77680.1 - 0.0038 16.9 0.0 0.012 15.3 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ77680.1 - 0.0051 17.2 0.0 0.011 16.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EEQ77680.1 - 0.0078 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EEQ77680.1 - 0.022 14.3 0.0 0.045 13.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ77680.1 - 0.11 12.9 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S24e PF01282.14 EEQ77681.1 - 1.5e-33 114.4 0.1 2.3e-33 113.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e FAD_binding_4 PF01565.18 EEQ77681.1 - 0.15 11.5 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain Pro_isomerase PF00160.16 EEQ77683.1 - 1.2e-36 126.3 0.0 1.8e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EEQ77683.1 - 5.3e-16 58.0 0.0 1.1e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ77683.1 - 1.4e-11 44.2 0.0 3.7e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ77683.1 - 3.4e-10 39.6 0.0 9.7e-10 38.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEQ77683.1 - 0.089 12.5 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Hepatitis_core PF00906.15 EEQ77683.1 - 3.6 7.1 19.3 9.7 5.8 13.2 1.8 1 1 1 2 2 2 0 Hepatitis core antigen UDPGP PF01704.13 EEQ77684.1 - 7.4e-54 182.8 0.0 1e-53 182.3 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EEQ77684.1 - 0.046 13.8 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 MobA-like NTP transferase domain zf-CCHC PF00098.18 EEQ77685.1 - 4.3e-39 130.6 57.6 2.2e-07 30.4 0.6 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EEQ77685.1 - 1e-08 34.6 42.1 0.064 12.9 0.4 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 EEQ77685.1 - 3.2e-06 26.7 39.4 0.0096 15.6 0.0 6.9 3 2 3 6 6 6 5 Zinc knuckle zf-CCHC_2 PF13696.1 EEQ77685.1 - 0.081 12.4 0.3 0.081 12.4 0.2 7.0 4 2 3 7 7 7 0 Zinc knuckle Rad51 PF08423.6 EEQ77686.1 - 7.5e-126 418.2 0.0 1.1e-125 417.7 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 EEQ77686.1 - 1.6e-11 43.8 0.0 2e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 EEQ77686.1 - 6.9e-11 41.9 0.0 1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 EEQ77686.1 - 1.6e-09 37.7 2.0 2.6e-09 37.0 0.1 2.2 3 0 0 3 3 3 1 Helix-hairpin-helix domain KaiC PF06745.8 EEQ77686.1 - 1.3e-08 34.3 0.0 3.2e-08 32.9 0.0 1.7 2 1 0 2 2 2 1 KaiC RNA_pol_A_CTD PF03118.10 EEQ77686.1 - 0.067 12.6 0.1 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain RRP7 PF12923.2 EEQ77687.1 - 1.4e-17 63.9 16.3 2.4e-15 56.7 9.0 2.5 2 1 1 3 3 3 2 Ribosomal RNA-processing protein 7 (RRP7) FAM176 PF14851.1 EEQ77690.1 - 0.021 14.5 1.1 0.041 13.5 0.4 1.7 1 1 1 2 2 2 0 FAM176 family Nucleoplasmin PF03066.10 EEQ77690.1 - 0.03 13.8 2.3 0.049 13.1 1.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF2890 PF11081.3 EEQ77690.1 - 0.051 13.6 2.4 0.061 13.3 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) UDG PF03167.14 EEQ77690.1 - 0.12 11.8 0.0 0.48 9.8 0.0 1.8 1 1 1 2 2 2 0 Uracil DNA glycosylase superfamily TIP_N PF12457.3 EEQ77690.1 - 0.24 11.4 7.6 0.35 10.9 5.3 1.2 1 0 0 1 1 1 0 Tuftelin interacting protein N terminal CDC45 PF02724.9 EEQ77690.1 - 0.25 9.3 3.6 0.29 9.1 2.5 1.0 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 EEQ77690.1 - 0.25 10.2 2.1 0.23 10.4 1.0 1.4 1 1 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Spt5_N PF11942.3 EEQ77690.1 - 0.27 11.8 10.5 0.41 11.3 7.3 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal PRP38_assoc PF12871.2 EEQ77690.1 - 1 9.9 8.9 1.3 9.5 6.1 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Myc_N PF01056.13 EEQ77690.1 - 2.5 7.1 7.4 2 7.5 4.8 1.3 1 1 0 1 1 1 0 Myc amino-terminal region RRM_1 PF00076.17 EEQ77691.1 - 2.2e-45 152.1 0.0 7.8e-17 60.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ77691.1 - 3.6e-27 94.1 0.0 1.9e-09 37.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ77691.1 - 1.9e-20 72.4 0.0 2.6e-08 33.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EEQ77691.1 - 1.3e-05 24.9 0.0 9.7e-05 22.1 0.0 2.2 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 EEQ77691.1 - 0.00039 20.1 0.0 0.0085 15.8 0.0 2.7 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif DND1_DSRM PF14709.1 EEQ77694.1 - 4.3e-05 23.7 1.0 0.0023 18.2 0.3 2.8 2 1 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 EEQ77694.1 - 0.011 16.3 2.0 0.07 13.7 0.2 3.0 3 0 0 3 3 3 0 Double-stranded RNA binding motif LisH PF08513.6 EEQ77695.1 - 0.00021 20.9 0.1 0.00039 20.0 0.1 1.4 1 0 0 1 1 1 1 LisH WD40 PF00400.27 EEQ77698.1 - 1.2e-49 164.4 5.1 6.6e-08 32.1 0.3 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EEQ77698.1 - 0.0037 16.0 0.9 0.061 12.0 0.1 2.6 1 1 2 3 3 3 2 Nup133 N terminal like TRAPP PF04051.11 EEQ77699.1 - 8.3e-31 106.5 0.0 1e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4250 PF14056.1 EEQ77699.1 - 0.031 13.9 0.1 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) Nucleopor_Nup85 PF07575.8 EEQ77701.1 - 3.1e-25 88.4 0.9 3.8e-11 41.9 0.0 3.8 3 1 0 3 3 3 3 Nup85 Nucleoporin APH PF01636.18 EEQ77702.1 - 4.3e-08 33.1 0.0 6.7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1676 PF07898.8 EEQ77703.1 - 0.027 14.7 0.1 3.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) AAA PF00004.24 EEQ77705.1 - 5.3e-05 23.4 0.0 0.00023 21.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEQ77705.1 - 0.0017 18.3 0.0 0.0026 17.7 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain CPT PF07931.7 EEQ77705.1 - 0.0019 17.8 0.0 0.0043 16.6 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.1 EEQ77705.1 - 0.025 15.3 0.0 0.082 13.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EEQ77705.1 - 0.068 13.3 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EEQ77705.1 - 0.091 12.6 0.3 1.9 8.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.12 EEQ77705.1 - 0.12 11.7 0.0 0.29 10.5 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 EEQ77705.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF568 PF04526.8 EEQ77707.1 - 0.079 13.2 0.1 0.24 11.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF568) ADH_N PF08240.7 EEQ77709.1 - 3.3e-12 46.1 0.3 5.8e-12 45.3 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ77709.1 - 8.6e-08 31.7 0.0 1.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADIP PF11559.3 EEQ77710.1 - 7.4e-30 103.8 15.1 1.3e-21 77.0 9.7 4.5 5 0 0 5 5 5 3 Afadin- and alpha -actinin-Binding VEK-30 PF12107.3 EEQ77710.1 - 2.5 7.9 5.7 0.72 9.6 0.1 2.6 2 0 0 2 2 2 0 Plasminogen (Pg) ligand in fibrinolytic pathway FUSC PF04632.7 EEQ77710.1 - 3.9 5.7 4.9 7.6 4.8 3.4 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Baculo_PEP_C PF04513.7 EEQ77710.1 - 7.1 6.4 8.7 11 5.7 0.5 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus F-box-like PF12937.2 EEQ77711.1 - 2.5e-07 30.3 1.9 9.8e-07 28.4 0.3 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EEQ77711.1 - 0.00015 21.3 2.7 0.00016 21.2 0.3 2.4 2 0 0 2 2 2 1 F-box domain PRANC PF09372.5 EEQ77711.1 - 0.00043 20.1 0.1 0.0015 18.4 0.1 2.0 1 0 0 1 1 1 1 PRANC domain LRR_4 PF12799.2 EEQ77711.1 - 0.00093 18.7 28.5 0.0021 17.6 0.6 7.8 4 2 3 8 8 8 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EEQ77711.1 - 0.009 15.9 12.8 3.5 7.9 0.0 7.3 9 0 0 9 9 9 1 Leucine Rich repeat TPR_11 PF13414.1 EEQ77711.1 - 0.034 13.7 0.0 0.79 9.4 0.3 2.6 2 1 1 3 3 3 0 TPR repeat TPR_1 PF00515.23 EEQ77711.1 - 0.071 12.7 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat LRR_7 PF13504.1 EEQ77711.1 - 1.3 9.5 19.5 1.4 9.4 0.2 8.1 9 2 1 10 10 10 0 Leucine rich repeat IDO PF01231.13 EEQ77712.1 - 1.7e-43 148.6 0.0 2.6e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Glyco_hydro_16 PF00722.16 EEQ77714.1 - 2.1e-09 36.9 0.1 4.9e-09 35.7 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 MFS_1 PF07690.11 EEQ77715.1 - 3.4e-37 127.9 45.3 5.3e-28 97.7 18.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EEQ77715.1 - 1.9e-08 33.1 23.0 2.4e-07 29.5 2.8 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein OATP PF03137.15 EEQ77715.1 - 0.096 10.7 3.3 0.32 9.0 1.1 2.6 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF697 PF05128.7 EEQ77715.1 - 4.6 6.7 9.7 5.1 6.5 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF697) CLTH PF10607.4 EEQ77716.1 - 9.3e-35 119.4 0.0 1.8e-34 118.5 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EEQ77716.1 - 1.4e-20 73.6 0.3 2.7e-20 72.6 0.2 1.5 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 EEQ77716.1 - 0.0053 16.4 0.0 0.032 13.9 0.0 2.2 2 0 0 2 2 2 1 LisH INO80_Ies4 PF08193.6 EEQ77717.1 - 1.8e-53 181.8 22.0 1.8e-53 181.8 15.3 3.2 1 1 0 2 2 2 1 INO80 complex subunit Ies4 DnaJ PF00226.26 EEQ77718.1 - 2.7e-13 49.4 0.5 4.9e-13 48.5 0.0 1.7 2 0 0 2 2 2 1 DnaJ domain SHS2_Rpb7-N PF03876.12 EEQ77719.1 - 1.8e-05 24.7 0.0 3.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Peptidase_S64 PF08192.6 EEQ77719.1 - 1.4 7.1 7.0 2.2 6.5 4.8 1.2 1 0 0 1 1 1 0 Peptidase family S64 Pyr_redox_2 PF07992.9 EEQ77720.1 - 3.6e-30 105.3 0.0 7e-30 104.4 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEQ77720.1 - 3.2e-14 53.0 0.5 7.1e-12 45.5 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EEQ77720.1 - 3e-12 45.9 0.0 7.4e-12 44.6 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EEQ77720.1 - 3.1e-07 30.6 0.0 0.001 19.2 0.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 EEQ77720.1 - 7e-06 26.2 0.0 4.3e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 Reductase C-terminal Rieske_2 PF13806.1 EEQ77720.1 - 0.00012 21.7 0.0 0.00039 20.1 0.0 1.9 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NAD_binding_9 PF13454.1 EEQ77720.1 - 0.00014 21.6 1.3 0.42 10.3 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 EEQ77720.1 - 0.00046 19.2 0.0 0.49 9.2 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EEQ77720.1 - 0.022 13.2 0.2 5.6 5.3 0.0 2.9 3 0 0 3 3 3 0 HI0933-like protein DUF1188 PF06690.6 EEQ77720.1 - 0.025 13.7 0.1 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Kelch_1 PF01344.20 EEQ77720.1 - 0.028 13.9 0.1 0.071 12.6 0.1 1.7 1 0 0 1 1 1 0 Kelch motif TrkA_N PF02254.13 EEQ77720.1 - 0.097 12.6 1.5 7.9 6.5 0.1 2.6 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_7 PF13241.1 EEQ77720.1 - 0.14 12.4 0.2 1.9 8.7 0.0 2.3 1 1 1 2 2 2 0 Putative NAD(P)-binding Arrestin_N PF00339.24 EEQ77722.1 - 1.9e-15 56.9 0.0 1.2e-09 38.1 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.5 EEQ77722.1 - 0.0022 17.1 0.4 0.0053 15.8 0.3 1.5 1 0 0 1 1 1 1 Rgp1 DUF3025 PF11227.3 EEQ77722.1 - 0.038 13.5 0.2 0.073 12.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) Bul1_C PF04426.7 EEQ77722.1 - 0.068 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Bul1 C terminus adh_short PF00106.20 EEQ77724.1 - 0.0013 18.6 0.1 0.0027 17.6 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NIF PF03031.13 EEQ77731.1 - 1.8e-39 134.9 0.1 2.6e-39 134.4 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EEQ77731.1 - 0.019 15.2 0.1 0.059 13.5 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase JAB PF01398.16 EEQ77732.1 - 5.5e-36 122.7 0.1 1e-35 121.9 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EEQ77732.1 - 1e-26 93.3 1.3 2.3e-26 92.1 0.9 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EEQ77732.1 - 7.8e-09 35.0 0.0 1.4e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UCR_14kD PF02271.11 EEQ77732.1 - 0.021 14.6 0.1 0.05 13.3 0.1 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Hist_deacetyl PF00850.14 EEQ77733.1 - 1.3e-77 261.1 0.1 2e-77 260.5 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DUF605 PF04652.11 EEQ77733.1 - 5.2 6.3 29.8 7 5.9 20.7 1.2 1 0 0 1 1 1 0 Vta1 like Ribosomal_L14 PF00238.14 EEQ77734.1 - 8.2e-33 112.7 0.0 9.2e-33 112.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Metallophos PF00149.23 EEQ77735.1 - 1.2e-07 31.3 4.3 0.00035 20.0 1.1 3.1 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase PH PF00169.24 EEQ77736.1 - 4.3e-11 42.9 0.0 1.1e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.12 EEQ77736.1 - 2.9e-08 33.4 0.1 5.2e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 EEQ77736.1 - 2e-07 31.2 0.0 7.1e-07 29.4 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_1 PF00018.23 EEQ77736.1 - 5.3e-07 28.9 0.0 1e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEQ77736.1 - 7.4e-07 28.6 0.1 1.5e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EEQ77736.1 - 0.0022 17.4 0.1 0.0044 16.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 EEQ77736.1 - 0.003 17.6 0.1 0.0074 16.4 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.1 EEQ77736.1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Agenet PF05641.7 EEQ77736.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Agenet domain Enterotoxin_ST PF02048.11 EEQ77737.1 - 0.082 13.1 6.0 0.17 12.1 4.2 1.6 1 0 0 1 1 1 0 Heat-stable enterotoxin ST Pkinase PF00069.20 EEQ77738.1 - 0.015 14.4 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain HSDR_N_2 PF13588.1 EEQ77738.1 - 0.052 13.3 0.0 0.39 10.5 0.0 2.2 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) APH PF01636.18 EEQ77738.1 - 0.75 9.4 5.1 0.75 9.4 1.2 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family BAR PF03114.13 EEQ77739.1 - 1e-62 211.6 4.4 1.3e-62 211.3 3.1 1.1 1 0 0 1 1 1 1 BAR domain Cast PF10174.4 EEQ77739.1 - 0.0023 16.0 4.7 0.003 15.6 3.3 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone HrpB2 PF09487.5 EEQ77739.1 - 0.024 14.8 1.9 0.046 13.9 0.2 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) BAR_2 PF10455.4 EEQ77739.1 - 0.16 10.8 4.9 1.3 7.8 3.4 2.0 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking FliD_N PF02465.13 EEQ77739.1 - 0.16 12.3 3.5 8.2 6.8 0.3 2.4 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF3450 PF11932.3 EEQ77739.1 - 7.7 5.6 9.9 2.3 7.4 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Pkinase PF00069.20 EEQ77740.1 - 3.9e-64 216.2 0.0 6e-64 215.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ77740.1 - 3.4e-27 95.1 0.0 4.8e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEQ77740.1 - 0.0088 15.1 0.0 0.021 13.8 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEQ77740.1 - 0.015 14.3 0.0 0.032 13.2 0.0 1.5 1 1 0 1 1 1 0 Kinase-like XPC-binding PF09280.6 EEQ77741.1 - 3.8e-23 80.7 14.6 7.2e-23 79.8 10.1 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 EEQ77741.1 - 1.6e-21 75.4 0.4 2.5e-21 74.8 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EEQ77741.1 - 2.7e-17 62.0 0.1 1.9e-08 33.9 0.0 2.8 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 EEQ77741.1 - 2e-08 33.7 0.4 3.4e-08 33.0 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EEQ77741.1 - 0.0047 16.7 0.0 0.0089 15.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rap1_C PF11626.3 EEQ77741.1 - 0.022 14.6 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain UBA_3 PF09288.5 EEQ77741.1 - 0.023 14.2 0.0 4 7.1 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain MCM_N PF14551.1 EEQ77741.1 - 0.029 14.8 0.0 0.058 13.8 0.0 1.5 1 0 0 1 1 1 0 MCM N-terminal domain DUF2407 PF10302.4 EEQ77741.1 - 0.037 14.2 0.0 0.097 12.8 0.0 1.7 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 EEQ77741.1 - 0.12 12.5 0.9 0.18 12.0 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2360 PF10152.4 EEQ77741.1 - 0.35 11.1 10.8 1.5 9.0 2.0 2.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF3431 PF11913.3 EEQ77742.1 - 6.9e-73 244.7 0.0 7.9e-73 244.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) zf-C3HC4_2 PF13923.1 EEQ77743.1 - 2.5e-08 33.7 10.1 4.2e-08 33.0 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ77743.1 - 6.3e-08 32.1 4.8 1e-07 31.4 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEQ77743.1 - 6.1e-07 29.1 6.6 9.6e-07 28.5 4.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EEQ77743.1 - 7.3e-07 28.8 8.5 1.2e-06 28.1 5.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EEQ77743.1 - 1.5e-06 27.7 10.2 2.6e-06 27.0 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 EEQ77743.1 - 5.2e-06 26.0 2.3 9.3e-06 25.1 1.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_UBOX PF13445.1 EEQ77743.1 - 0.0064 16.1 5.5 0.014 15.1 3.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EEQ77743.1 - 0.0073 16.1 8.6 0.015 15.1 6.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EEQ77743.1 - 0.029 13.8 2.6 0.053 13.0 1.8 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Cript PF10235.4 EEQ77743.1 - 0.031 14.6 3.1 0.13 12.5 2.1 2.1 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT U79_P34 PF03064.11 EEQ77743.1 - 1 8.8 10.6 0.021 14.3 1.7 2.1 2 0 0 2 2 2 0 HSV U79 / HCMV P34 zf-rbx1 PF12678.2 EEQ77743.1 - 1.8 8.7 5.4 4.5 7.4 3.8 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger Mcp5_PH PF12814.2 EEQ77745.1 - 5.6e-45 152.2 0.3 1.5e-44 150.8 0.2 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology DUF2296 PF10058.4 EEQ77746.1 - 0.034 13.8 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) DUF3405 PF11885.3 EEQ77747.1 - 3.4e-175 583.0 1.3 4.2e-175 582.7 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Methyltransf_23 PF13489.1 EEQ77748.1 - 2.3e-15 56.6 0.0 3.9e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ77748.1 - 5.7e-07 29.9 0.0 0.00011 22.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ77748.1 - 6.8e-07 29.6 0.0 2e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ77748.1 - 0.00019 21.0 0.0 0.0022 17.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ77748.1 - 0.00025 21.6 0.0 0.00041 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEQ77748.1 - 0.037 13.1 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NodS PF05401.6 EEQ77748.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF2439 PF10382.4 EEQ77749.1 - 2.7e-27 94.7 0.1 4.4e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) SH3_9 PF14604.1 EEQ77751.1 - 1.9e-14 52.9 0.1 3.5e-14 52.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEQ77751.1 - 8e-14 50.7 0.1 1.6e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain BAR PF03114.13 EEQ77751.1 - 2.4e-12 46.8 1.1 3.7e-12 46.2 0.7 1.2 1 0 0 1 1 1 1 BAR domain SH3_2 PF07653.12 EEQ77751.1 - 3.6e-10 39.1 0.0 6.8e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF4131 PF13567.1 EEQ77752.1 - 0.31 10.4 7.4 2.1 7.7 2.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Nckap1 PF09735.4 EEQ77753.1 - 0.61 7.4 0.1 0.86 6.9 0.1 1.1 1 0 0 1 1 1 0 Membrane-associated apoptosis protein Exo_endo_phos PF03372.18 EEQ77756.1 - 1.5e-20 74.2 0.6 2e-20 73.8 0.4 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RTC PF01137.16 EEQ77757.1 - 5.8e-35 120.1 0.0 1.4e-22 79.6 0.0 3.0 2 1 0 2 2 2 2 RNA 3'-terminal phosphate cyclase DUF488 PF04343.8 EEQ77758.1 - 1.9e-21 76.7 0.0 2.9e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF488 ETF PF01012.16 EEQ77759.1 - 1.3e-36 125.8 0.9 1.7e-36 125.4 0.6 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Flavodoxin_1 PF00258.20 EEQ77760.1 - 2.8e-31 108.4 0.0 5.6e-31 107.4 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 EEQ77760.1 - 6.4e-29 100.9 0.0 2.8e-28 98.8 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EEQ77760.1 - 2e-15 57.2 0.0 6.2e-15 55.7 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EEQ77760.1 - 1e-05 25.5 0.0 0.00014 21.8 0.0 2.5 2 1 1 3 3 3 1 Flavodoxin domain Flavodoxin_3 PF12641.2 EEQ77760.1 - 0.0031 16.9 0.0 0.018 14.4 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin domain RNA_pol_3_Rpc31 PF11705.3 EEQ77761.1 - 1.5e-34 120.0 41.2 1.9e-33 116.3 28.6 2.2 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Proteasom_PSMB PF10508.4 EEQ77762.1 - 0.23 9.6 0.2 6.1 4.9 0.0 2.4 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit JAB PF01398.16 EEQ77763.1 - 2.9e-10 39.8 0.0 6.3e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EEQ77763.1 - 9.9e-05 22.4 0.3 0.0049 16.9 0.2 3.0 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function P4Ha_N PF08336.6 EEQ77763.1 - 0.013 15.3 0.1 0.024 14.4 0.1 1.4 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region SAP PF02037.22 EEQ77764.1 - 2.1e-09 36.6 0.0 3.5e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 SAP domain CN_hydrolase PF00795.17 EEQ77766.1 - 1.6e-11 43.8 0.0 9.4e-11 41.4 0.0 2.1 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase DUF1176 PF06674.6 EEQ77767.1 - 0.008 15.3 0.4 0.013 14.6 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1176) DUF1661 PF07877.6 EEQ77767.1 - 0.054 13.0 0.2 0.15 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1661) Tho2 PF11262.3 EEQ77768.1 - 4.5e-94 314.8 0.0 6.5e-94 314.3 0.0 1.2 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EEQ77768.1 - 1.1e-30 105.2 0.0 5.8e-30 102.9 0.0 2.2 2 0 0 2 2 2 1 Transcription- and export-related complex subunit MFS_1 PF07690.11 EEQ77769.1 - 4.1e-29 101.3 46.6 1e-28 100.0 32.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ77769.1 - 0.00015 20.5 14.9 0.00015 20.5 10.3 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter Epimerase PF01370.16 EEQ77770.1 - 6.8e-11 42.0 0.1 1e-05 25.0 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EEQ77770.1 - 1.3e-07 31.8 0.1 3.4e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 EEQ77770.1 - 1.1e-05 24.8 0.0 1.6e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EEQ77770.1 - 0.0076 14.9 0.0 0.061 12.0 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EEQ77770.1 - 0.05 13.6 0.0 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding NAD_binding_4 PF07993.7 EEQ77770.1 - 0.074 11.9 0.0 0.37 9.6 0.0 2.0 2 1 1 3 3 3 0 Male sterility protein GFA PF04828.9 EEQ77771.1 - 3.1e-15 55.8 0.2 5.1e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Herpes_UL49_1 PF03117.9 EEQ77771.1 - 0.0012 18.0 0.9 0.0015 17.6 0.6 1.1 1 0 0 1 1 1 1 UL49 family Rpr2 PF04032.11 EEQ77771.1 - 0.13 12.1 1.0 1.7 8.5 0.0 2.1 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Vps5 PF09325.5 EEQ77773.1 - 8.2e-16 57.9 2.8 1.3e-15 57.2 1.9 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EEQ77773.1 - 2.7e-08 33.6 0.0 8.8e-08 31.9 0.0 1.9 2 0 0 2 2 2 1 PX domain TPR_12 PF13424.1 EEQ77773.1 - 0.017 15.0 1.4 0.074 12.9 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat GTP_EFTU PF00009.22 EEQ77774.1 - 1.3e-54 184.5 0.0 2.2e-54 183.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EEQ77774.1 - 2.5e-25 88.1 0.1 5.3e-25 87.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EEQ77774.1 - 4.3e-19 68.1 0.1 6.9e-09 35.4 0.0 2.4 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EEQ77774.1 - 7.2e-05 22.8 0.0 0.00024 21.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEQ77774.1 - 0.033 14.1 0.0 0.088 12.7 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase ArfGap PF01412.13 EEQ77775.1 - 5.9e-29 100.2 0.0 9.7e-29 99.5 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RRM_1 PF00076.17 EEQ77776.1 - 2.8e-29 100.5 0.0 2.9e-14 52.4 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ77776.1 - 3.3e-22 78.2 0.0 2.7e-11 43.2 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ77776.1 - 7.9e-07 28.8 0.0 0.0063 16.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 EEQ77776.1 - 0.017 13.6 4.0 0.023 13.2 2.8 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) MARVEL PF01284.18 EEQ77779.1 - 1.8e-05 24.5 9.6 0.00016 21.5 6.8 2.0 1 1 1 2 2 2 2 Membrane-associating domain BCCT PF02028.12 EEQ77779.1 - 0.0089 14.3 1.0 0.25 9.5 0.0 2.0 2 0 0 2 2 2 2 BCCT family transporter Kelch_4 PF13418.1 EEQ77781.1 - 9.1e-14 50.9 9.7 5.6e-07 29.2 0.2 5.5 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EEQ77781.1 - 2.1e-13 49.9 4.2 1.1e-08 34.7 0.1 4.8 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 EEQ77781.1 - 4.5e-06 26.6 7.7 0.065 13.4 0.4 5.4 5 1 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 EEQ77781.1 - 3.2e-05 23.9 14.1 0.75 10.0 0.2 5.8 5 1 0 5 5 5 3 Galactose oxidase, central domain SKG6 PF08693.5 EEQ77781.1 - 0.005 16.1 0.1 0.013 14.8 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_1 PF01344.20 EEQ77781.1 - 0.034 13.6 7.4 0.53 9.8 0.1 4.5 4 1 0 4 4 4 0 Kelch motif Beta-APP PF03494.8 EEQ77781.1 - 0.32 10.5 3.5 0.73 9.3 2.4 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Methyltransf_3 PF01596.12 EEQ77782.1 - 0.013 14.5 0.0 0.036 13.0 0.0 1.6 1 1 1 2 2 2 0 O-methyltransferase Methyltransf_24 PF13578.1 EEQ77782.1 - 0.018 15.8 0.0 0.032 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CmcI PF04989.7 EEQ77782.1 - 0.026 13.8 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase DNase_NucA_NucB PF14040.1 EEQ77782.1 - 0.099 12.8 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Deoxyribonuclease NucA/NucB GFO_IDH_MocA PF01408.17 EEQ77784.1 - 1.5e-25 90.0 0.1 3.2e-25 88.9 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EEQ77784.1 - 2.2e-14 53.2 0.0 3.9e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EEQ77784.1 - 0.00049 20.4 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.15 EEQ77784.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 EEQ77784.1 - 0.044 14.2 0.0 0.096 13.1 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 EEQ77784.1 - 0.054 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sec62 PF03839.11 EEQ77786.1 - 0.12 11.8 3.4 0.25 10.7 2.4 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 HPP PF04982.8 EEQ77788.1 - 4.4e-33 113.6 6.7 4.4e-33 113.6 4.6 1.7 2 0 0 2 2 2 1 HPP family Bax1-I PF01027.15 EEQ77788.1 - 1.4 8.4 13.0 0.41 10.2 2.2 2.3 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 DUF4131 PF13567.1 EEQ77788.1 - 3.8 6.8 8.2 0.84 9.0 2.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) ABC_tran PF00005.22 EEQ77789.1 - 8.8e-47 158.8 0.0 1.2e-23 83.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EEQ77789.1 - 6.2e-21 75.6 0.1 0.00023 21.2 0.0 4.3 3 1 1 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 EEQ77789.1 - 5e-19 67.9 0.8 5e-19 67.9 0.6 2.7 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.14 EEQ77789.1 - 6.7e-11 41.8 0.2 0.0032 16.7 0.0 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EEQ77789.1 - 4.1e-09 35.8 0.2 0.00051 19.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EEQ77789.1 - 2.9e-08 34.2 1.4 0.021 15.1 0.0 3.7 3 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 EEQ77789.1 - 2.1e-07 30.2 0.0 0.00045 19.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EEQ77789.1 - 2.3e-06 28.4 0.3 0.021 15.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EEQ77789.1 - 5.7e-06 26.6 0.2 0.05 13.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EEQ77789.1 - 2.8e-05 24.2 0.0 0.19 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EEQ77789.1 - 6e-05 22.2 0.0 0.081 11.9 0.0 2.8 3 0 0 3 3 2 2 AAA ATPase domain NACHT PF05729.7 EEQ77789.1 - 8.4e-05 22.2 0.1 0.35 10.5 0.0 2.5 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.17 EEQ77789.1 - 9.2e-05 22.5 1.0 0.92 9.7 0.0 3.4 3 0 0 3 3 3 2 RNA helicase MMR_HSR1 PF01926.18 EEQ77789.1 - 0.0001 22.2 0.0 0.2 11.6 0.0 2.9 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EEQ77789.1 - 0.0001 22.3 0.0 0.43 10.5 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain MobB PF03205.9 EEQ77789.1 - 0.00023 20.8 0.3 0.0069 16.0 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EEQ77789.1 - 0.00027 21.1 0.0 0.74 10.0 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EEQ77789.1 - 0.00027 21.4 0.0 0.55 10.7 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein Arch_ATPase PF01637.13 EEQ77789.1 - 0.00061 19.5 0.1 0.64 9.6 0.0 3.0 3 0 0 3 3 3 1 Archaeal ATPase AAA_5 PF07728.9 EEQ77789.1 - 0.00061 19.5 0.0 1.5 8.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EEQ77789.1 - 0.00067 19.6 0.0 0.5 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EEQ77789.1 - 0.00074 18.4 0.1 0.41 9.4 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain AAA_10 PF12846.2 EEQ77789.1 - 0.0017 17.8 2.0 0.76 9.1 0.2 2.8 3 0 0 3 3 2 2 AAA-like domain AAA_33 PF13671.1 EEQ77789.1 - 0.0017 18.2 1.9 0.16 11.8 0.0 3.0 4 0 0 4 4 2 1 AAA domain AAA_25 PF13481.1 EEQ77789.1 - 0.0019 17.6 0.1 0.3 10.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EEQ77789.1 - 0.0097 15.8 0.0 3.6 7.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EEQ77789.1 - 0.011 15.6 0.4 0.86 9.5 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 EEQ77789.1 - 0.02 13.7 0.2 3.8 6.2 0.1 2.6 2 0 0 2 2 2 0 ArgK protein AAA_30 PF13604.1 EEQ77789.1 - 0.025 14.1 0.5 9.7 5.7 0.0 3.2 4 0 0 4 4 4 0 AAA domain PduV-EutP PF10662.4 EEQ77789.1 - 0.028 13.9 0.5 2.1 7.8 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 EEQ77789.1 - 0.028 13.3 0.0 3.9 6.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Dynamin_N PF00350.18 EEQ77789.1 - 0.03 14.1 0.0 21 4.9 0.0 3.6 2 1 1 3 3 3 0 Dynamin family ATP-synt_ab PF00006.20 EEQ77789.1 - 0.037 13.5 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain VirE PF05272.6 EEQ77789.1 - 0.048 13.1 0.1 1.8 8.0 0.0 2.8 3 0 0 3 3 3 0 Virulence-associated protein E DUF2813 PF11398.3 EEQ77789.1 - 0.052 12.6 0.0 12 4.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) DAP3 PF10236.4 EEQ77789.1 - 0.054 12.4 0.1 9.6 5.0 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.1 EEQ77789.1 - 0.097 12.2 1.0 14 5.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 EEQ77789.1 - 0.14 11.8 0.2 6.9 6.3 0.1 2.5 2 0 0 2 2 2 0 NTPase Gly-zipper_OmpA PF13436.1 EEQ77790.1 - 3.9 7.1 16.4 0.044 13.4 4.3 2.2 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DUF2309 PF10070.4 EEQ77791.1 - 0.0056 14.8 0.1 0.0061 14.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2309) UQ_con PF00179.21 EEQ77792.1 - 5.1e-42 142.6 0.0 7.2e-42 142.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EEQ77792.1 - 1.5e-05 24.4 0.0 2.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain DUF2095 PF09868.4 EEQ77792.1 - 0.1 12.4 0.1 0.18 11.5 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) RWD PF05773.17 EEQ77792.1 - 0.14 12.0 0.1 0.14 12.0 0.1 1.6 2 1 0 2 2 2 0 RWD domain AAA PF00004.24 EEQ77793.1 - 4.1e-41 140.2 0.0 8.8e-41 139.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEQ77793.1 - 2.6e-07 30.8 0.2 0.00013 22.1 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EEQ77793.1 - 2.4e-06 27.5 0.0 5.4e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EEQ77793.1 - 5.4e-05 22.2 0.0 9e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EEQ77793.1 - 8.1e-05 22.3 0.1 0.00023 20.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EEQ77793.1 - 0.00094 19.2 0.1 0.005 16.8 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EEQ77793.1 - 0.00095 18.2 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EEQ77793.1 - 0.00098 19.1 0.5 0.0026 17.7 0.1 2.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEQ77793.1 - 0.0013 18.4 0.4 0.0031 17.2 0.3 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EEQ77793.1 - 0.0041 16.5 0.0 0.0088 15.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EEQ77793.1 - 0.0089 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 EEQ77793.1 - 0.012 15.2 0.2 0.72 9.4 0.1 2.4 1 1 1 2 2 2 0 NACHT domain TIP49 PF06068.8 EEQ77793.1 - 0.013 14.2 0.1 0.033 12.9 0.0 1.6 1 1 0 1 1 1 0 TIP49 C-terminus AAA_14 PF13173.1 EEQ77793.1 - 0.017 15.0 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EEQ77793.1 - 0.02 15.7 0.3 0.059 14.1 0.2 2.0 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EEQ77793.1 - 0.023 13.8 0.4 0.29 10.2 0.1 2.2 1 1 1 2 2 2 0 KaiC PhoH PF02562.11 EEQ77793.1 - 0.024 13.8 1.0 0.46 9.6 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.1 EEQ77793.1 - 0.035 14.4 0.0 0.085 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EEQ77793.1 - 0.035 13.6 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EEQ77793.1 - 0.061 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EEQ77793.1 - 0.077 11.8 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.4 EEQ77793.1 - 0.078 11.9 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EEQ77793.1 - 0.085 13.0 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 EEQ77793.1 - 0.12 11.4 0.1 0.24 10.5 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EEQ77793.1 - 0.13 11.8 0.2 0.35 10.3 0.2 1.7 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 EEQ77793.1 - 0.28 11.0 1.5 2.7 7.8 0.0 2.9 4 0 0 4 4 3 0 Shikimate kinase AAA_25 PF13481.1 EEQ77793.1 - 0.46 9.8 5.2 0.57 9.5 0.3 2.6 2 1 1 3 3 3 0 AAA domain AMP-binding PF00501.23 EEQ77795.1 - 6e-80 268.6 0.0 7.4e-80 268.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ77795.1 - 4.8e-12 46.6 0.1 1.1e-11 45.5 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1772 PF08592.6 EEQ77796.1 - 0.0032 17.1 0.2 0.0063 16.2 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF401 PF04165.7 EEQ77796.1 - 0.13 11.2 0.1 0.16 10.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF401) adh_short_C2 PF13561.1 EEQ77797.1 - 4.7e-20 72.3 0.0 6.7e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEQ77797.1 - 1.3e-17 64.1 0.9 1.9e-17 63.6 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ77797.1 - 3.8e-05 23.4 0.2 7.7e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 KR domain DUF3584 PF12128.3 EEQ77798.1 - 0.0011 16.4 14.1 0.0011 16.4 9.8 2.8 3 1 1 4 4 4 1 Protein of unknown function (DUF3584) IncA PF04156.9 EEQ77798.1 - 1.7 8.2 32.0 0.46 10.0 14.0 3.2 2 1 0 2 2 2 0 IncA protein FlaC_arch PF05377.6 EEQ77798.1 - 2.1 8.2 12.0 6.9 6.6 2.5 3.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) RabGAP-TBC PF00566.13 EEQ77800.1 - 2.8e-45 154.4 0.0 4.4e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 EEQ77800.1 - 0.0071 15.8 0.0 0.045 13.2 0.0 2.3 2 1 0 2 2 2 1 GRAM domain EF-hand_7 PF13499.1 EEQ77800.1 - 0.1 12.7 1.3 0.72 10.0 0.1 3.0 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.1 EEQ77800.1 - 0.12 12.3 0.1 0.12 12.3 0.0 3.7 4 0 0 4 4 4 0 EF-hand domain Sigma70_ner PF04546.8 EEQ77800.1 - 8.3 5.9 9.5 15 5.1 0.6 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region CNH PF00780.17 EEQ77801.1 - 6.1e-64 216.0 0.0 1.1e-63 215.2 0.0 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EEQ77801.1 - 1.1e-32 113.3 0.8 1.8e-32 112.6 0.5 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EEQ77801.1 - 1.9e-13 50.4 0.0 2e-12 47.2 0.0 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EEQ77801.1 - 0.0023 18.1 0.0 0.0075 16.4 0.0 1.9 1 0 0 1 1 1 1 PH domain DUF4551 PF15087.1 EEQ77801.1 - 0.51 8.6 0.0 0.51 8.6 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4551) AMP-binding PF00501.23 EEQ77803.1 - 4.1e-74 249.4 0.0 5.2e-74 249.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ77803.1 - 1.2e-11 45.3 0.1 2.7e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AFT PF08731.6 EEQ77804.1 - 0.0088 16.2 0.1 0.013 15.7 0.1 1.5 1 1 0 1 1 1 1 Transcription factor AFT FAR1 PF03101.10 EEQ77804.1 - 0.056 13.9 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 FAR1 DNA-binding domain WD40 PF00400.27 EEQ77805.1 - 6.7e-29 98.6 1.3 1e-06 28.3 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EEQ77805.1 - 0.002 17.6 0.0 0.043 13.3 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain NDUF_B12 PF08122.7 EEQ77806.1 - 4.2e-17 61.6 2.1 6.4e-17 61.0 1.4 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family CAF1 PF04857.15 EEQ77807.1 - 1.7e-65 220.9 0.0 2.8e-65 220.2 0.0 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease Cu_amine_oxid PF01179.15 EEQ77808.1 - 4.6e-139 463.7 2.1 2e-91 306.7 2.3 2.2 1 1 1 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EEQ77808.1 - 1.2e-13 50.9 0.0 2.1e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EEQ77808.1 - 1.1e-08 35.0 0.0 2.1e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Asp PF00026.18 EEQ77809.1 - 1e-58 199.1 0.0 1.2e-58 198.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EEQ77809.1 - 5.1e-05 22.8 0.0 0.00014 21.4 0.0 1.7 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EEQ77809.1 - 0.0017 18.8 0.1 0.9 10.0 0.0 2.6 2 1 0 2 2 2 2 Aspartyl protease RVP PF00077.15 EEQ77809.1 - 0.067 13.1 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease DUF4219 PF13961.1 EEQ77810.1 - 0.00077 18.8 1.4 0.0011 18.2 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) UBN2 PF14223.1 EEQ77810.1 - 0.0017 18.1 3.2 0.0042 16.8 0.0 2.2 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EEQ77810.1 - 0.0038 16.7 4.3 1.9 8.0 0.1 3.3 2 1 0 2 2 2 2 gag-polypeptide of LTR copia-type SSP160 PF06933.6 EEQ77810.1 - 1.3 6.9 9.2 2 6.3 6.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pox_A_type_inc PF04508.7 EEQ77810.1 - 3.9 7.5 5.7 11 6.0 4.0 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat TPR_11 PF13414.1 EEQ77812.1 - 3e-11 42.7 0.0 4.5e-08 32.6 0.0 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EEQ77812.1 - 8.3e-08 31.5 0.3 0.33 10.9 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ77812.1 - 1e-05 24.9 0.0 0.32 10.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ77812.1 - 0.0014 18.8 0.0 0.045 14.0 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EEQ77812.1 - 0.0047 17.0 0.0 0.036 14.1 0.0 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EEQ77812.1 - 0.0058 16.4 0.0 0.028 14.2 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ77812.1 - 0.0075 15.9 0.0 2.8 7.9 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ77812.1 - 0.0088 15.9 0.6 4.4 7.2 0.0 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ77812.1 - 0.022 15.3 0.5 14 6.6 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ77812.1 - 0.08 13.6 0.1 17 6.2 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ77812.1 - 0.14 12.7 2.5 1.2 9.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat GRAM PF02893.15 EEQ77813.1 - 6.8e-17 60.7 0.0 1.3e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Calpain_inhib PF00748.14 EEQ77815.1 - 0.013 15.8 1.2 0.013 15.8 0.8 2.7 2 1 1 3 3 3 0 Calpain inhibitor SCP-1 PF05483.7 EEQ77815.1 - 0.11 10.2 0.1 0.16 9.7 0.1 1.1 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) Med30 PF11315.3 EEQ77815.1 - 0.24 11.4 0.8 0.97 9.5 0.0 2.1 2 0 0 2 2 2 0 Mediator complex subunit 30 Striatin PF08232.7 EEQ77815.1 - 0.28 11.4 6.2 0.36 11.1 0.7 2.5 2 0 0 2 2 2 0 Striatin family HALZ PF02183.13 EEQ77815.1 - 0.56 9.9 4.0 5.5 6.7 1.1 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Tropomyosin PF00261.15 EEQ77815.1 - 4.9 6.1 9.5 0.2 10.7 1.9 1.9 2 0 0 2 2 2 0 Tropomyosin Mg_trans_NIPA PF05653.9 EEQ77816.1 - 3.7e-57 193.5 10.0 1.4e-32 112.8 0.2 3.1 2 1 1 3 3 3 3 Magnesium transporter NIPA EmrE PF13536.1 EEQ77816.1 - 4.2e-06 26.9 9.8 1.4e-05 25.2 0.3 2.8 2 0 0 2 2 2 1 Multidrug resistance efflux transporter CD20 PF04103.10 EEQ77816.1 - 0.0057 16.5 1.1 1.3 8.9 0.0 3.5 3 0 0 3 3 3 1 CD20-like family EamA PF00892.15 EEQ77816.1 - 0.0062 16.5 1.4 0.0062 16.5 0.9 3.6 4 0 0 4 4 4 1 EamA-like transporter family DoxX_2 PF13564.1 EEQ77816.1 - 0.14 12.0 4.9 1.3 9.0 0.1 2.7 2 0 0 2 2 2 0 DoxX-like family WD40 PF00400.27 EEQ77817.1 - 2.1e-21 74.9 15.3 5e-07 29.3 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat OPT PF03169.10 EEQ77818.1 - 2.9e-34 118.5 19.2 1.1e-27 96.8 0.1 4.0 3 1 1 4 4 4 4 OPT oligopeptide transporter protein Pro_dh PF01619.13 EEQ77819.1 - 0.027 13.4 0.1 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Proline dehydrogenase DUF4286 PF14114.1 EEQ77819.1 - 0.062 13.5 0.1 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) DUF4041 PF13250.1 EEQ77819.1 - 0.11 12.0 0.0 0.54 9.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) Z1 PF10593.4 EEQ77819.1 - 1 8.5 4.5 3.3 6.8 0.2 2.9 2 1 1 3 3 3 0 Z1 domain DUF706 PF05153.10 EEQ77820.1 - 8.7e-130 431.4 0.3 1e-129 431.2 0.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 EEQ77820.1 - 0.04 13.9 0.1 0.69 9.9 0.0 2.5 3 0 0 3 3 3 0 HD domain RTA1 PF04479.8 EEQ77821.1 - 1.6e-44 152.0 0.8 2.2e-44 151.6 0.6 1.1 1 0 0 1 1 1 1 RTA1 like protein GFA PF04828.9 EEQ77822.1 - 3.4e-08 33.3 7.4 2.6e-06 27.2 0.0 2.6 2 1 1 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Romo1 PF10247.4 EEQ77825.1 - 0.062 13.5 1.2 3.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 DUF500 PF04366.7 EEQ77826.1 - 3.7e-39 133.0 0.0 7e-39 132.1 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) PARP PF00644.15 EEQ77827.1 - 9.1e-63 211.4 2.1 1e-62 211.2 0.0 2.1 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EEQ77827.1 - 4.9e-42 142.7 0.1 7.7e-42 142.1 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 EEQ77827.1 - 1.6e-20 72.7 0.1 5.6e-20 71.0 0.1 2.0 2 0 0 2 2 2 1 WGR domain BRCT PF00533.21 EEQ77827.1 - 1.5e-09 37.8 0.2 5.5e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Voldacs PF03517.8 EEQ77827.1 - 0.17 11.6 2.7 0.37 10.6 0.0 2.4 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling PTCB-BRCT PF12738.2 EEQ77827.1 - 0.23 11.3 1.7 0.59 10.0 0.0 2.4 2 0 0 2 2 2 0 twin BRCT domain WD40 PF00400.27 EEQ77828.1 - 8.8e-09 34.9 0.3 7.4e-08 31.9 0.1 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat TFIIS_C PF01096.13 EEQ77829.1 - 9.8e-15 53.9 1.4 1.6e-14 53.2 1.0 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Terminase_GpA PF05876.7 EEQ77829.1 - 0.0022 16.4 0.2 0.003 15.9 0.1 1.1 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) Baculo_LEF5_C PF11792.3 EEQ77829.1 - 0.0053 16.1 0.4 0.017 14.4 0.3 1.9 1 1 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain RNA_POL_M_15KD PF02150.11 EEQ77829.1 - 0.16 11.6 4.5 1.1 9.0 0.4 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit DUF2082 PF09855.4 EEQ77829.1 - 0.18 11.6 1.5 9.5 6.1 0.1 2.3 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-TFIIB PF13453.1 EEQ77829.1 - 0.64 9.2 2.8 0.47 9.6 0.3 2.0 2 0 0 2 2 2 0 Transcription factor zinc-finger MFS_1 PF07690.11 EEQ77831.1 - 6.6e-42 143.4 46.6 1.3e-40 139.1 30.7 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ77831.1 - 1e-14 53.9 19.2 1.1e-14 53.9 5.9 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter Chitin_synth_2 PF03142.10 EEQ77832.1 - 1.5e-293 974.0 0.8 1.9e-293 973.6 0.5 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EEQ77832.1 - 5.3e-18 65.4 0.1 5.3e-18 65.4 0.1 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EEQ77832.1 - 3.5e-15 56.4 0.0 1.4e-13 51.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EEQ77832.1 - 4.2e-08 32.8 0.0 8.1e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EEQ77832.1 - 4.1e-05 22.9 0.0 0.00046 19.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EEQ77832.1 - 0.0084 15.7 0.0 0.16 11.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Sel1 PF08238.7 EEQ77836.1 - 1.1e-35 121.2 28.0 5.1e-06 26.9 0.0 7.6 7 0 0 7 7 7 7 Sel1 repeat TPR_11 PF13414.1 EEQ77836.1 - 0.044 13.4 4.3 2.2 7.9 0.3 3.3 2 1 0 2 2 2 0 TPR repeat TPR_6 PF13174.1 EEQ77836.1 - 0.088 13.2 4.7 2.1 9.0 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ77836.1 - 3 8.6 17.7 0.22 12.2 0.3 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.11 EEQ77837.1 - 7e-45 153.2 56.8 7e-45 153.2 39.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ77837.1 - 7.4e-14 51.1 13.6 7.4e-14 51.1 9.4 3.3 2 2 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EEQ77837.1 - 2.8e-12 45.6 24.8 6.1e-12 44.5 16.6 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 EEQ77837.1 - 0.01 14.3 26.9 0.019 13.4 9.3 3.0 3 0 0 3 3 3 0 Vacuole effluxer Atg22 like Glyco_hydro_17 PF00332.13 EEQ77839.1 - 0.0088 15.1 0.1 1.1 8.2 0.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 AcetylCoA_hydro PF02550.10 EEQ77841.1 - 7.6e-50 169.4 0.0 1.1e-49 168.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 EEQ77841.1 - 4e-39 133.7 0.0 6.4e-39 133.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.18 EEQ77841.1 - 0.048 12.8 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Coenzyme A transferase PAH PF02671.16 EEQ77842.1 - 2.5e-46 155.0 1.0 6.8e-17 60.8 0.3 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EEQ77842.1 - 7.5e-42 141.2 0.6 1.9e-41 139.9 0.1 1.9 2 0 0 2 2 2 1 Sin3 family co-repressor DUF1777 PF08648.7 EEQ77842.1 - 1.9 8.1 28.1 0.11 12.1 14.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) MMPL PF03176.10 EEQ77842.1 - 2.4 6.8 3.3 0.7 8.5 0.0 1.7 2 0 0 2 2 2 0 MMPL family Amidase PF01425.16 EEQ77843.1 - 9.3e-83 278.5 0.3 1.3e-82 278.0 0.2 1.2 1 0 0 1 1 1 1 Amidase Pyr_redox_3 PF13738.1 EEQ77844.1 - 1.4e-27 97.1 0.0 2.6e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EEQ77844.1 - 4.4e-22 77.9 0.0 2.2e-21 75.6 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EEQ77844.1 - 5e-16 58.5 0.5 4.5e-13 48.8 0.1 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EEQ77844.1 - 1.9e-15 57.2 0.0 8.3e-11 42.1 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEQ77844.1 - 2.5e-10 40.5 0.2 0.00099 19.4 0.1 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EEQ77844.1 - 6.8e-09 35.2 4.6 0.00013 21.1 0.8 3.3 2 1 1 3 3 3 2 FAD binding domain 3HCDH_N PF02737.13 EEQ77844.1 - 3.1e-06 26.9 0.6 0.0024 17.5 0.1 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EEQ77844.1 - 2.1e-05 23.7 0.2 0.059 12.5 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 EEQ77844.1 - 3.5e-05 22.4 0.2 0.0061 15.0 0.1 3.1 3 0 0 3 3 3 1 HI0933-like protein ApbA PF02558.11 EEQ77844.1 - 3.6e-05 23.2 0.0 0.086 12.2 0.0 2.6 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 EEQ77844.1 - 0.00022 21.6 0.0 1.6 9.1 0.0 3.7 4 0 0 4 4 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_8 PF13450.1 EEQ77844.1 - 0.00027 20.8 0.0 0.011 15.7 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEQ77844.1 - 0.00035 19.6 1.4 0.84 8.4 0.2 3.3 3 1 0 4 4 4 1 FAD dependent oxidoreductase IlvN PF07991.7 EEQ77844.1 - 0.00069 19.0 0.5 0.0027 17.0 0.0 2.2 2 1 1 3 3 3 1 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 EEQ77844.1 - 0.0012 18.9 0.0 1.2 9.2 0.0 2.6 3 0 0 3 3 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 EEQ77844.1 - 0.0017 17.4 0.2 0.3 10.1 0.0 2.7 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.17 EEQ77844.1 - 0.0018 17.1 0.3 0.34 9.7 0.0 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 EEQ77844.1 - 0.0023 17.6 0.1 0.069 12.8 0.0 2.3 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.16 EEQ77844.1 - 0.0025 17.4 0.1 0.32 10.5 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 EEQ77844.1 - 0.0072 16.1 6.4 5.2 6.8 0.1 4.0 4 1 1 5 5 4 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EEQ77844.1 - 0.0073 16.5 0.2 0.11 12.7 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.19 EEQ77844.1 - 0.0077 15.1 4.1 0.067 12.0 0.5 3.0 2 1 0 3 3 3 1 FAD binding domain TrkA_N PF02254.13 EEQ77844.1 - 0.015 15.2 0.3 6.6 6.7 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_10 PF13460.1 EEQ77844.1 - 0.02 14.9 0.3 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 NADH(P)-binding SnoaL_2 PF12680.2 EEQ77844.1 - 0.027 14.8 2.2 0.094 13.1 0.2 2.7 3 0 0 3 3 2 0 SnoaL-like domain ThiF PF00899.16 EEQ77844.1 - 0.035 13.9 0.3 35 4.2 0.0 3.3 3 0 0 3 3 3 0 ThiF family Lycopene_cycl PF05834.7 EEQ77844.1 - 0.039 12.8 1.0 1.1 8.1 0.0 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein ELFV_dehydrog PF00208.16 EEQ77844.1 - 0.079 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Dicty_REP PF05086.7 EEQ77846.1 - 1.1 6.8 6.5 0.1 10.3 0.2 1.8 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein WD40 PF00400.27 EEQ77847.1 - 3.2e-13 48.9 2.2 0.41 10.5 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat PCI PF01399.22 EEQ77848.1 - 2.3e-11 43.9 0.0 7.1e-11 42.3 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.4 EEQ77848.1 - 3.6e-06 26.4 0.1 6.6e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_14 PF13428.1 EEQ77848.1 - 0.00023 21.4 4.5 1.7 9.5 0.3 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ77848.1 - 0.00092 19.5 1.3 0.025 14.9 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ77848.1 - 0.072 12.9 0.0 2.4 8.1 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TFIIF_beta PF02270.10 EEQ77849.1 - 8.1e-91 304.6 2.8 9.4e-91 304.4 1.9 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit zf-CCCH PF00642.19 EEQ77850.1 - 7.8e-14 50.9 24.5 0.00083 18.9 1.0 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EEQ77850.1 - 2.4 8.2 14.5 3.5 7.7 1.4 4.1 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type bZIP_Maf PF03131.12 EEQ77852.1 - 8.4e-05 22.8 16.5 8.4e-05 22.8 11.5 3.0 4 1 1 5 5 5 1 bZIP Maf transcription factor bZIP_2 PF07716.10 EEQ77852.1 - 9.6e-05 22.1 12.7 9.6e-05 22.1 8.8 3.4 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.16 EEQ77852.1 - 0.00017 21.5 11.0 0.00017 21.5 7.7 3.1 1 1 2 3 3 3 1 bZIP transcription factor Jnk-SapK_ap_N PF09744.4 EEQ77852.1 - 0.073 13.0 22.3 0.14 12.1 15.5 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Sel1 PF08238.7 EEQ77853.1 - 1.5e-18 66.7 2.1 4.1e-08 33.5 0.2 4.5 4 0 0 4 4 4 4 Sel1 repeat Pkinase PF00069.20 EEQ77854.1 - 2.6e-19 69.3 0.0 3.2e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ77854.1 - 7.4e-12 44.8 0.0 2.2e-06 26.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Mt_ATP-synt_B PF05405.9 EEQ77855.1 - 1.4e-50 170.9 12.4 1.7e-50 170.6 8.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Spore_III_AB PF09548.5 EEQ77855.1 - 0.35 10.5 3.9 0.54 9.9 1.7 1.8 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) CBF PF03914.12 EEQ77856.1 - 2e-48 163.9 3.1 2.1e-48 163.8 0.2 2.5 3 0 0 3 3 3 1 CBF/Mak21 family Utp12 PF04003.7 EEQ77856.1 - 0.036 13.9 0.3 0.13 12.1 0.2 2.0 1 1 0 1 1 1 0 Dip2/Utp12 Family AMP-binding PF00501.23 EEQ77858.1 - 3.5e-81 272.7 0.0 5.3e-81 272.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EEQ77858.1 - 1.3e-62 210.9 0.0 6.8e-61 205.3 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EEQ77858.1 - 7.3e-38 130.1 6.3 6.3e-35 120.5 2.4 2.7 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EEQ77858.1 - 4.4e-21 75.3 4.1 3.4e-18 65.9 1.6 2.5 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EEQ77858.1 - 1.3e-18 67.6 0.1 2.7e-18 66.6 0.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EEQ77858.1 - 5.1e-18 65.3 0.0 1.5e-09 37.6 0.0 2.9 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEQ77858.1 - 3.3e-12 45.6 0.0 4.3e-07 28.9 0.0 3.0 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 EEQ77858.1 - 1.3e-11 44.5 0.0 3.9e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 EEQ77858.1 - 3.2e-11 43.5 0.5 1.2e-06 28.6 0.8 3.9 3 1 0 3 3 3 2 NADH(P)-binding RmlD_sub_bind PF04321.12 EEQ77858.1 - 8.9e-08 31.3 0.3 0.0006 18.7 0.0 3.2 3 0 0 3 3 3 2 RmlD substrate binding domain AMP-binding_C PF13193.1 EEQ77858.1 - 7.5e-07 30.0 0.2 1.2e-05 26.2 0.1 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.10 EEQ77858.1 - 9.4e-07 28.0 0.8 0.0036 16.2 0.2 3.3 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein DFP PF04127.10 EEQ77858.1 - 0.0032 17.1 0.5 0.012 15.2 0.6 1.7 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Saccharop_dh PF03435.13 EEQ77858.1 - 0.02 13.8 0.3 0.04 12.8 0.2 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 EEQ77858.1 - 0.034 13.9 0.4 0.1 12.3 0.3 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EEQ77858.1 - 0.044 12.8 0.0 0.13 11.2 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.8 EEQ77858.1 - 0.075 12.2 0.9 3.7 6.7 0.8 2.9 3 0 0 3 3 3 0 NmrA-like family Pkinase PF00069.20 EEQ77859.1 - 9.8e-09 34.7 1.3 1.1e-07 31.2 0.9 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ77859.1 - 0.00011 21.3 0.1 0.00074 18.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase adh_short PF00106.20 EEQ77860.1 - 0.00023 21.1 0.0 0.00042 20.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ77860.1 - 0.00059 19.5 0.1 0.0018 17.9 0.0 1.8 2 0 0 2 2 2 1 KR domain Amidohydro_2 PF04909.9 EEQ77860.1 - 0.0036 16.9 0.0 0.0048 16.4 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Na_H_Exchanger PF00999.16 EEQ77861.1 - 2.4e-28 98.7 2.2 3.7e-28 98.1 1.5 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EEQ77861.1 - 0.013 15.4 1.4 0.026 14.4 0.1 2.2 2 1 0 2 2 2 0 YrhC-like protein GPI-anchored PF10342.4 EEQ77862.1 - 9.4e-20 70.8 0.8 9.4e-20 70.8 0.6 2.2 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Mucin PF01456.12 EEQ77862.1 - 0.001 18.8 16.9 0.001 18.8 11.7 2.0 2 0 0 2 2 2 1 Mucin-like glycoprotein Trypan_PARP PF05887.6 EEQ77862.1 - 0.016 15.0 2.3 0.034 13.9 1.6 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Menin PF05053.8 EEQ77862.1 - 0.083 11.0 1.5 0.091 10.9 1.0 1.2 1 0 0 1 1 1 0 Menin TFIIA PF03153.8 EEQ77863.1 - 1.9 8.3 17.7 2.2 8.1 12.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 EEQ77863.1 - 2.8 6.0 20.2 3.8 5.6 14.0 1.3 1 0 0 1 1 1 0 Transmembrane protein MMS19_C PF12460.3 EEQ77865.1 - 1.7e-126 422.2 11.5 1.7e-126 422.2 8.0 3.1 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 EEQ77865.1 - 3.7e-94 314.8 0.1 1.4e-92 309.7 0.0 3.0 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.17 EEQ77865.1 - 0.0077 16.2 9.9 34 4.8 0.1 7.1 7 0 0 7 7 7 0 HEAT repeat HEAT_EZ PF13513.1 EEQ77865.1 - 0.15 12.6 16.7 22 5.6 0.4 7.4 7 0 0 7 7 7 0 HEAT-like repeat DXP_synthase_N PF13292.1 EEQ77865.1 - 0.18 10.7 1.1 0.27 10.1 0.1 1.7 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Fasciclin PF02469.17 EEQ77866.1 - 0.021 14.8 0.0 0.046 13.7 0.0 1.6 1 1 0 1 1 1 0 Fasciclin domain DUF106 PF01956.11 EEQ77867.1 - 3.9e-55 185.9 0.2 5e-55 185.5 0.1 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 SPC25 PF06703.6 EEQ77868.1 - 1.8e-48 164.2 0.0 2e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) PDR_CDR PF06422.7 EEQ77868.1 - 0.16 11.6 1.0 0.29 10.8 0.5 1.5 1 1 0 1 1 1 0 CDR ABC transporter THF_DHG_CYH PF00763.18 EEQ77869.1 - 4e-17 62.3 0.0 6e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EEQ77869.1 - 1e-12 47.4 0.1 6.1e-09 35.1 0.0 2.7 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ATP-synt_ab PF00006.20 EEQ77870.1 - 2.6e-70 236.3 0.0 3.5e-70 235.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EEQ77870.1 - 3e-27 95.3 0.9 1.1e-26 93.5 0.2 2.3 2 1 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EEQ77870.1 - 3.6e-12 46.3 0.9 8.4e-12 45.1 0.7 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EEQ77870.1 - 0.087 12.7 0.4 0.68 9.8 0.2 2.5 2 1 0 2 2 2 0 HAS barrel domain AAA_25 PF13481.1 EEQ77870.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF962 PF06127.6 EEQ77871.1 - 6.2e-27 93.3 0.0 9.9e-27 92.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) PTPS_related PF10131.4 EEQ77872.1 - 0.044 11.9 0.0 0.046 11.8 0.0 1.1 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein SHS2_Rpb7-N PF03876.12 EEQ77873.1 - 6.2e-14 51.8 0.1 9.6e-14 51.2 0.1 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EEQ77873.1 - 2e-10 40.5 0.0 3.1e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 EEQ77873.1 - 0.073 13.2 0.1 0.19 11.9 0.0 1.7 1 1 1 2 2 2 0 RNA polymerase III subunit Rpc25 Macoilin PF09726.4 EEQ77874.1 - 7.3 4.7 6.3 9.4 4.3 4.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Fungal_trans PF04082.13 EEQ77875.1 - 4.6e-11 42.1 0.0 2.9e-07 29.6 0.0 2.4 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ77875.1 - 5.8e-07 29.3 13.1 1.1e-06 28.4 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.17 EEQ77876.1 - 3.4e-35 119.4 0.0 1.2e-18 66.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ77876.1 - 2.4e-29 101.0 0.1 5.1e-16 58.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ77876.1 - 6.4e-17 61.1 0.0 3.9e-12 45.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_11 PF13414.1 EEQ77877.1 - 5e-27 93.3 3.8 3e-11 42.8 0.1 4.5 3 1 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 EEQ77877.1 - 1e-25 88.2 1.6 2.4e-09 36.3 0.0 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ77877.1 - 1.6e-24 83.7 1.8 1.3e-07 30.9 0.0 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ77877.1 - 1.3e-19 68.9 1.6 2.2e-05 24.7 0.3 5.8 5 1 1 6 6 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ77877.1 - 4.8e-17 60.6 2.1 0.00081 19.3 0.0 5.1 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ77877.1 - 1.1e-15 57.7 10.6 1.1e-05 25.9 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ77877.1 - 6.3e-15 55.2 3.2 0.0004 20.6 0.0 4.5 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ77877.1 - 2.3e-14 53.0 1.7 1.8e-07 31.0 0.1 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ77877.1 - 9.6e-14 50.0 0.1 3.4e-05 23.3 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ77877.1 - 1.1e-11 43.6 3.2 0.00061 19.3 0.0 6.4 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_20 PF14561.1 EEQ77877.1 - 1.4e-09 37.8 4.9 0.0019 18.3 0.0 4.8 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ77877.1 - 2.6e-09 36.7 0.4 0.0061 16.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ77877.1 - 1.4e-07 31.5 1.6 1.7 9.2 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 EEQ77877.1 - 2e-07 31.0 0.7 0.00012 22.1 0.1 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EEQ77877.1 - 0.011 15.5 0.5 0.45 10.5 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EEQ77877.1 - 0.012 15.4 0.3 4.4 7.2 0.0 3.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_15 PF13429.1 EEQ77877.1 - 0.024 13.6 5.4 1.2 8.1 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 EEQ77877.1 - 0.031 14.0 0.0 3 7.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TOM20_plant PF06552.7 EEQ77877.1 - 0.042 13.4 0.0 4 6.9 0.0 2.9 2 1 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 DUF4192 PF13830.1 EEQ77877.1 - 7.7 6.0 8.0 4.2 6.9 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4192) TPP_enzyme_N PF02776.13 EEQ77878.1 - 3.4e-47 160.1 0.1 8.5e-47 158.8 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EEQ77878.1 - 4.7e-35 120.3 0.0 8.6e-35 119.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EEQ77878.1 - 4.8e-19 68.4 0.0 1.9e-18 66.5 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Glyco_trans_4_4 PF13579.1 EEQ77878.1 - 0.076 13.1 0.1 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain ERO1 PF04137.10 EEQ77879.1 - 5.8e-132 440.0 0.0 9.9e-132 439.2 0.0 1.3 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) MSP1_C PF07462.6 EEQ77879.1 - 0.26 9.6 0.0 0.4 8.9 0.0 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Peroxin-13_N PF04088.8 EEQ77880.1 - 2.7e-60 202.9 0.0 4.2e-60 202.2 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EEQ77880.1 - 7.4e-10 38.1 0.0 1.2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEQ77880.1 - 2.9e-07 29.7 0.0 5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEQ77880.1 - 2.9e-06 26.7 0.1 4.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Cytochrom_B_N PF00033.14 EEQ77880.1 - 0.065 12.5 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB APG6 PF04111.7 EEQ77882.1 - 7.9e-130 432.5 0.0 1e-129 432.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Rpr2 PF04032.11 EEQ77882.1 - 0.046 13.5 1.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Stress-antifung PF01657.12 EEQ77882.1 - 0.071 13.4 0.2 0.97 9.7 0.0 2.6 3 0 0 3 3 3 0 Salt stress response/antifungal Scm3 PF10384.4 EEQ77883.1 - 1.9e-23 81.6 0.4 3.9e-23 80.7 0.3 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 Myb_DNA-bind_6 PF13921.1 EEQ77883.1 - 0.18 11.9 1.6 1.2 9.2 0.0 2.7 2 1 1 3 3 3 0 Myb-like DNA-binding domain PALP PF00291.20 EEQ77884.1 - 5.1e-52 176.9 0.0 1e-51 176.0 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.12 EEQ77885.1 - 9.6e-40 136.5 0.0 1.5e-39 135.9 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 EEQ77885.1 - 0.073 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF3116 PF11313.3 EEQ77886.1 - 0.017 14.6 0.2 0.032 13.8 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3116) F-box-like PF12937.2 EEQ77887.1 - 2.6e-06 27.0 0.1 7.6e-06 25.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ77887.1 - 2e-05 24.1 0.0 6.3e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 F-box domain DUF1886 PF09171.5 EEQ77887.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1886) Phg_2220_C PF09524.5 EEQ77890.1 - 0.14 12.1 0.2 0.32 11.0 0.1 1.6 1 1 1 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) RTC4 PF14474.1 EEQ77891.1 - 2e-22 79.4 0.0 2.1e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 RTC4-like domain Cys_Met_Meta_PP PF01053.15 EEQ77893.1 - 2e-137 457.5 0.1 2.3e-137 457.4 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EEQ77893.1 - 2.4e-08 33.3 0.1 3.6e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EEQ77893.1 - 1.8e-05 23.6 0.4 3.4e-05 22.7 0.1 1.5 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EEQ77893.1 - 2.7e-05 23.3 0.3 6.2e-05 22.1 0.2 1.6 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EEQ77893.1 - 0.0002 20.5 0.1 0.0003 20.0 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 EEQ77893.1 - 0.051 12.2 0.1 0.081 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein NmrA PF05368.8 EEQ77894.1 - 1.4e-13 50.6 0.0 1.8e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 EEQ77894.1 - 0.013 14.5 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase ThiF PF00899.16 EEQ77894.1 - 0.16 11.7 0.0 3 7.6 0.0 2.2 2 0 0 2 2 2 0 ThiF family RNA_pol_Rbc25 PF08292.7 EEQ77895.1 - 4.7e-37 126.8 0.0 6.4e-37 126.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EEQ77895.1 - 9.7e-16 57.6 0.0 1.7e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EEQ77895.1 - 0.015 15.3 0.0 0.042 13.9 0.0 1.8 1 1 0 1 1 1 0 S1 RNA binding domain ThuA PF06283.6 EEQ77895.1 - 0.097 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Trehalose utilisation NUFIP1 PF10453.4 EEQ77896.1 - 6.5e-15 54.3 6.4 6.5e-15 54.3 4.4 3.0 3 0 0 3 3 3 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 EEQ77896.1 - 5.8e-09 35.4 2.7 9.8e-09 34.6 1.9 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Muted PF14942.1 EEQ77897.1 - 0.0068 16.2 5.9 0.01 15.6 4.1 1.3 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein HsdM_N PF12161.3 EEQ77897.1 - 0.024 15.0 0.8 0.028 14.8 0.6 1.3 1 1 0 1 1 1 0 HsdM N-terminal domain DUF607 PF04678.8 EEQ77897.1 - 0.033 14.1 0.5 0.044 13.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF607 Prominin PF05478.6 EEQ77897.1 - 0.034 11.6 0.1 0.038 11.5 0.1 1.0 1 0 0 1 1 1 0 Prominin DUF2031 PF09592.5 EEQ77897.1 - 0.096 11.8 9.3 0.14 11.3 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) DUF342 PF03961.8 EEQ77897.1 - 0.15 10.4 4.1 0.17 10.2 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 EEQ77897.1 - 0.15 11.5 3.7 0.19 11.3 2.6 1.2 1 0 0 1 1 1 0 IncA protein DUF964 PF06133.6 EEQ77897.1 - 0.17 11.9 4.1 0.34 10.9 2.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF964) Med4 PF10018.4 EEQ77897.1 - 0.23 10.8 5.7 0.36 10.1 4.0 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 CemA PF03040.9 EEQ77897.1 - 0.31 10.6 1.2 0.39 10.3 0.8 1.1 1 0 0 1 1 1 0 CemA family CorA PF01544.13 EEQ77897.1 - 0.36 9.8 3.1 0.58 9.1 2.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CHD5 PF04420.9 EEQ77897.1 - 0.43 10.2 2.8 0.57 9.8 2.0 1.3 1 0 0 1 1 1 0 CHD5-like protein Fib_alpha PF08702.5 EEQ77897.1 - 0.5 10.4 3.0 0.65 10.1 0.9 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Fzo_mitofusin PF04799.8 EEQ77897.1 - 0.5 9.7 3.0 1 8.7 2.0 1.5 1 1 0 1 1 1 0 fzo-like conserved region Transposase_22 PF02994.9 EEQ77897.1 - 0.78 8.1 9.8 1 7.7 6.8 1.2 1 0 0 1 1 1 0 L1 transposable element Bap31 PF05529.7 EEQ77897.1 - 0.88 8.9 5.5 1.2 8.5 3.8 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF4164 PF13747.1 EEQ77897.1 - 0.99 9.5 8.3 2.3 8.3 5.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) DUF972 PF06156.8 EEQ77897.1 - 1.1 9.6 8.2 2.6 8.4 5.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) TMF_DNA_bd PF12329.3 EEQ77897.1 - 3.3 7.5 17.3 0.81 9.5 6.2 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding FemAB PF02388.11 EEQ77897.1 - 5.7 5.5 7.0 22 3.5 4.8 1.8 1 1 0 1 1 1 0 FemAB family VitD-bind_III PF09164.5 EEQ77898.1 - 0.061 12.9 0.3 0.16 11.5 0.2 1.7 1 0 0 1 1 1 0 Vitamin D binding protein, domain III YopX PF09643.5 EEQ77898.1 - 0.086 12.8 0.3 0.13 12.1 0.2 1.4 1 1 0 1 1 1 0 YopX protein GPI-anchored PF10342.4 EEQ77900.1 - 5.8e-23 81.1 0.4 5.8e-23 81.1 0.3 2.5 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EEQ77900.1 - 2.4e-05 23.9 0.2 6.4e-05 22.5 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Macoilin PF09726.4 EEQ77900.1 - 2.7 6.1 11.3 3.2 5.9 7.8 1.0 1 0 0 1 1 1 0 Transmembrane protein Dicty_REP PF05086.7 EEQ77900.1 - 5.7 4.5 8.3 6.8 4.3 5.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DNA_pol_viral_N PF00242.12 EEQ77900.1 - 9.1 5.1 9.4 11 4.8 6.5 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain RRM_1 PF00076.17 EEQ77901.1 - 3e-07 29.9 0.0 1.3e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ77901.1 - 1.3e-05 25.0 0.0 4.5e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ77901.1 - 0.028 14.2 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sds3 PF08598.6 EEQ77902.1 - 4.7e-23 81.7 7.8 4.7e-23 81.7 5.4 3.0 2 2 1 3 3 3 1 Sds3-like DUF1487 PF07368.6 EEQ77902.1 - 0.0033 16.6 0.1 0.0053 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) TMEM247 PF15444.1 EEQ77902.1 - 9 6.0 8.7 0.18 11.5 0.2 2.2 2 1 0 2 2 2 0 Transmembrane protein 247 DUF3725 PF12523.3 EEQ77903.1 - 0.044 13.8 0.4 0.062 13.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) Ole-e-6 PF09253.5 EEQ77903.1 - 0.064 12.9 0.3 0.064 12.9 0.2 2.3 2 1 1 3 3 3 0 Pollen allergen ole e 6 Coiled-coil_56 PF09813.4 EEQ77906.1 - 9.9e-06 25.4 0.0 1e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.3 EEQ77907.1 - 2.1e-69 233.5 2.0 4.1e-68 229.3 1.4 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3453) TPR_12 PF13424.1 EEQ77908.1 - 1.4e-13 50.5 0.0 2.2e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 EEQ77908.1 - 1.4e-10 40.7 0.1 0.0046 16.8 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ77908.1 - 0.0098 16.5 0.1 4.7 7.9 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EEQ77908.1 - 0.0098 15.5 0.0 0.39 10.4 0.0 2.8 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 EEQ77908.1 - 0.056 13.3 3.5 20 5.3 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ77908.1 - 0.2 11.3 2.0 2.2 8.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat STT3 PF02516.9 EEQ77909.1 - 1.6e-133 446.2 38.4 1.8e-128 429.5 25.2 2.2 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Dpy19 PF10034.4 EEQ77909.1 - 0.018 13.2 0.1 0.018 13.2 0.0 2.1 2 0 0 2 2 2 0 Q-cell neuroblast polarisation PCI_Csn8 PF10075.4 EEQ77910.1 - 2.1e-26 92.4 0.2 2.9e-26 91.9 0.1 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EEQ77910.1 - 5.2e-05 22.9 0.3 6.2e-05 22.6 0.2 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family RasGAP PF00616.14 EEQ77910.1 - 0.01 15.4 0.1 0.014 15.0 0.1 1.1 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase ATP-synt_E PF05680.7 EEQ77911.1 - 4.1e-23 81.1 0.1 5e-23 80.8 0.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain WD40 PF00400.27 EEQ77912.1 - 2e-15 55.9 5.4 9.3e-05 22.1 0.1 5.3 4 1 0 4 4 4 4 WD domain, G-beta repeat Spore_III_AF PF09581.5 EEQ77912.1 - 0.072 12.9 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Dynein_IC2 PF11540.3 EEQ77912.1 - 0.16 11.4 0.5 0.54 9.6 0.1 2.1 2 0 0 2 2 2 0 Cytoplasmic dynein 1 intermediate chain 2 Kri1 PF05178.7 EEQ77912.1 - 2.8 8.2 7.8 13 6.1 0.3 2.4 2 0 0 2 2 2 0 KRI1-like family Atg14 PF10186.4 EEQ77912.1 - 5.8 5.7 6.8 0.56 9.1 0.9 1.9 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 MFS_1 PF07690.11 EEQ77913.1 - 1.4e-34 119.4 29.9 1.4e-34 119.4 20.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_Coat_B PF05356.6 EEQ77913.1 - 1.5 8.5 4.5 0.86 9.3 0.7 2.1 2 0 0 2 2 2 0 Phage Coat protein B Prenyltrans_1 PF13243.1 EEQ77914.1 - 0.12 12.4 0.3 0.24 11.4 0.2 1.5 1 0 0 1 1 1 0 Prenyltransferase-like PMT PF02366.13 EEQ77915.1 - 6.2e-80 268.0 16.8 1.1e-79 267.2 11.6 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EEQ77915.1 - 1.5e-17 63.7 1.0 4.6e-17 62.1 0.3 1.9 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.1 EEQ77915.1 - 0.00085 19.2 10.6 0.00085 19.2 7.3 3.1 5 1 0 5 5 5 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Pirin PF02678.11 EEQ77916.1 - 2e-32 111.2 0.1 3.7e-32 110.3 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EEQ77916.1 - 5.1e-22 77.9 0.0 2.5e-21 75.7 0.0 2.0 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EEQ77916.1 - 3.9e-05 23.0 0.9 0.00057 19.3 1.3 2.2 2 0 0 2 2 2 1 Cupin domain PRKCSH PF07915.8 EEQ77917.1 - 1.1e-18 67.7 0.1 1.1e-18 67.7 0.0 2.4 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein SH3_1 PF00018.23 EEQ77919.1 - 7.1e-36 121.3 6.4 9.3e-14 50.5 0.0 4.3 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.7 EEQ77919.1 - 6.1e-35 118.7 0.0 1.1e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 EEQ77919.1 - 3.4e-31 106.5 6.4 4.4e-13 48.5 0.1 4.0 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 EEQ77919.1 - 1.1e-21 76.0 0.1 2.1e-07 30.3 0.0 4.4 4 0 0 4 4 4 3 Variant SH3 domain SH3_3 PF08239.6 EEQ77919.1 - 0.0011 19.0 2.1 0.043 14.0 0.1 3.3 3 0 0 3 3 3 1 Bacterial SH3 domain SAM_1 PF00536.25 EEQ77919.1 - 0.058 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) HSCB_C PF07743.8 EEQ77921.1 - 1.3e-19 70.4 0.8 5.7e-19 68.3 0.2 2.0 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EEQ77921.1 - 7.5e-11 41.6 0.0 1.4e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain AIG2 PF06094.7 EEQ77922.1 - 0.0015 18.9 0.2 0.002 18.5 0.1 1.2 1 0 0 1 1 1 1 AIG2-like family F-box-like PF12937.2 EEQ77923.1 - 3.4e-06 26.6 0.2 7.1e-06 25.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ77923.1 - 4.7e-06 26.0 0.3 1.4e-05 24.6 0.2 1.8 2 0 0 2 2 2 1 F-box domain DUF951 PF06107.6 EEQ77923.1 - 0.043 13.3 0.9 0.13 11.8 0.1 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) Arrestin_N PF00339.24 EEQ77924.1 - 2.6e-09 37.0 0.0 2e-08 34.1 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain WD40 PF00400.27 EEQ77925.1 - 2.7e-48 160.2 19.5 9.4e-11 41.1 0.3 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EEQ77925.1 - 2e-15 55.7 3.0 4e-15 54.7 2.1 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like DUF4165 PF13752.1 EEQ77925.1 - 0.079 12.7 0.0 4.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4165) PRTP PF01366.13 EEQ77925.1 - 0.21 9.5 0.1 0.28 9.1 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein DUF4611 PF15387.1 EEQ77925.1 - 0.29 11.3 3.8 0.55 10.4 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Sigma70_ner PF04546.8 EEQ77925.1 - 0.3 10.6 6.5 0.46 10.0 4.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Acetyltransf_1 PF00583.19 EEQ77927.1 - 0.0002 21.3 0.0 0.0013 18.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEQ77927.1 - 0.0018 18.3 0.0 0.0035 17.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEQ77927.1 - 0.015 15.4 0.0 0.033 14.3 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEQ77927.1 - 0.14 12.1 0.0 0.31 10.9 0.0 1.6 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase TPR_2 PF07719.12 EEQ77928.1 - 0.00068 19.3 0.0 1.2 9.1 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ77928.1 - 0.0024 17.4 0.0 3.8 7.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat ERG4_ERG24 PF01222.12 EEQ77929.1 - 7.7e-89 298.1 9.3 9.1e-89 297.9 6.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EEQ77929.1 - 0.00033 20.0 0.4 0.00076 18.8 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) DUF2919 PF11143.3 EEQ77929.1 - 0.025 14.3 4.7 1.9 8.2 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2919) SpoIIE PF07228.7 EEQ77930.1 - 8.2e-11 41.9 0.1 2.8e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EEQ77930.1 - 5.1e-09 35.8 0.1 5.1e-09 35.8 0.1 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C PF00481.16 EEQ77930.1 - 1.8e-07 30.7 0.1 0.00022 20.7 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C RVT_2 PF07727.9 EEQ77930.1 - 0.076 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Peroxidase_2 PF01328.12 EEQ77932.1 - 8.5e-14 50.9 0.3 4.9e-11 41.8 0.1 2.2 2 0 0 2 2 2 2 Peroxidase, family 2 GMC_oxred_C PF05199.8 EEQ77936.1 - 7.4e-31 107.3 0.0 1.3e-30 106.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EEQ77936.1 - 2.1e-24 86.2 0.0 1.5e-18 67.0 0.0 3.2 3 0 0 3 3 3 3 GMC oxidoreductase Pyr_redox_2 PF07992.9 EEQ77936.1 - 0.0033 17.3 0.0 0.007 16.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEQ77936.1 - 0.0061 16.5 0.1 0.016 15.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEQ77936.1 - 0.018 13.9 0.3 1.2 7.9 0.2 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EEQ77936.1 - 0.028 13.3 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EEQ77936.1 - 0.068 12.0 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 EEQ77936.1 - 0.074 12.0 0.1 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HHH PF00633.18 EEQ77936.1 - 0.41 10.4 2.9 6 6.7 0.0 3.4 3 0 0 3 3 3 0 Helix-hairpin-helix motif PAP2_3 PF14378.1 EEQ77937.1 - 7.7e-12 45.1 27.8 0.00014 21.4 2.3 4.8 3 1 0 4 4 4 3 PAP2 superfamily PAP2 PF01569.16 EEQ77937.1 - 1.1 8.8 16.1 0.32 10.6 5.3 3.4 2 2 1 3 3 3 0 PAP2 superfamily PWWP PF00855.12 EEQ77938.1 - 1.9e-12 47.1 3.5 1.9e-12 47.1 2.5 2.7 2 1 0 2 2 2 1 PWWP domain RTC PF01137.16 EEQ77939.1 - 1.2e-30 106.0 0.0 1.7e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EEQ77939.1 - 6.2e-30 103.2 0.0 1.1e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain 3-HAO PF06052.7 EEQ77940.1 - 2.7e-55 185.9 0.0 3.2e-55 185.6 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EEQ77940.1 - 0.00019 20.8 0.0 0.00033 20.0 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EEQ77940.1 - 0.016 14.8 0.1 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_1 PF00190.17 EEQ77940.1 - 0.038 13.4 0.0 0.088 12.2 0.0 1.6 1 0 0 1 1 1 0 Cupin TF_Zn_Ribbon PF08271.7 EEQ77940.1 - 6.9 6.0 6.9 36 3.7 1.2 2.8 1 1 1 2 2 2 0 TFIIB zinc-binding CAP_GLY PF01302.20 EEQ77941.1 - 6.2e-17 61.0 0.6 1.3e-16 59.9 0.4 1.6 1 0 0 1 1 1 1 CAP-Gly domain AAA_13 PF13166.1 EEQ77941.1 - 0.0021 16.5 4.9 0.0021 16.5 3.4 2.6 3 0 0 3 3 3 1 AAA domain Spc7 PF08317.6 EEQ77941.1 - 0.021 13.4 20.7 0.014 14.1 5.0 2.9 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF812 PF05667.6 EEQ77941.1 - 0.39 9.1 21.0 0.09 11.2 6.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.7 EEQ77941.1 - 1.9 8.2 21.1 0.015 15.0 6.8 2.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein PilJ PF13675.1 EEQ77941.1 - 2.9 8.2 14.8 0.34 11.2 2.5 3.4 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term PVL_ORF50 PF07768.6 EEQ77941.1 - 7.5 6.5 12.7 0.097 12.6 0.7 2.8 2 1 1 3 3 3 0 PVL ORF-50-like family TMF_DNA_bd PF12329.3 EEQ77941.1 - 8.8 6.2 29.5 12 5.7 2.1 5.3 4 1 1 5 5 5 0 TATA element modulatory factor 1 DNA binding Fez1 PF06818.10 EEQ77941.1 - 9.1 6.2 27.3 5.8 6.8 15.5 2.6 2 1 0 2 2 2 0 Fez1 Pkinase PF00069.20 EEQ77942.1 - 8.8e-37 126.6 0.0 1.6e-20 73.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ77942.1 - 1.4e-12 47.2 0.0 0.00051 19.1 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 EEQ77942.1 - 0.0015 17.5 0.0 0.85 8.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EEQ77942.1 - 0.0065 16.2 0.1 0.02 14.6 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Peptidase_S9 PF00326.16 EEQ77943.1 - 6.6e-53 179.0 0.0 1.9e-51 174.3 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEQ77943.1 - 8.1e-09 35.3 0.0 1.5e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EEQ77943.1 - 0.00043 19.7 0.0 0.001 18.5 0.0 1.6 1 1 0 1 1 1 1 Putative esterase AXE1 PF05448.7 EEQ77943.1 - 0.0034 15.9 0.1 0.019 13.5 0.0 1.8 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.4 EEQ77943.1 - 0.018 14.2 0.0 0.1 11.8 0.0 1.9 2 0 0 2 2 2 0 Esterase PHB depolymerase Sec63 PF02889.11 EEQ77944.1 - 5e-195 646.8 0.3 1.9e-107 359.1 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EEQ77944.1 - 1.5e-53 180.7 3.1 9.9e-32 109.7 0.0 4.6 5 0 0 5 5 5 2 DEAD/DEAH box helicase ResIII PF04851.10 EEQ77944.1 - 2.1e-16 60.2 0.0 2.7e-09 37.1 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EEQ77944.1 - 1.3e-10 40.9 0.0 1.6e-09 37.4 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EEQ77944.1 - 2.4e-07 30.9 0.3 0.001 19.2 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_10 PF12846.2 EEQ77944.1 - 0.00037 20.0 0.0 3.3 7.0 0.0 4.3 4 1 1 5 5 5 2 AAA-like domain T2SE PF00437.15 EEQ77944.1 - 0.001 18.0 0.0 0.12 11.2 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.1 EEQ77944.1 - 0.0055 16.4 0.0 2 8.2 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain PhoH PF02562.11 EEQ77944.1 - 0.0076 15.5 0.0 1.8 7.7 0.0 2.9 3 0 0 3 3 3 1 PhoH-like protein MutS_V PF00488.16 EEQ77945.1 - 1.2e-84 283.4 0.0 2.2e-84 282.5 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EEQ77945.1 - 8e-39 133.5 9.0 1.3e-38 132.8 6.2 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EEQ77945.1 - 1.3e-21 76.7 0.0 3.2e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EEQ77945.1 - 1.3e-07 31.8 0.0 5.5e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EEQ77945.1 - 0.0028 17.7 0.0 0.007 16.5 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 EEQ77945.1 - 0.11 12.0 0.0 0.33 10.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ureidogly_hydro PF04115.7 EEQ77946.1 - 1.9e-48 163.9 0.0 4.2e-48 162.8 0.0 1.5 1 1 0 1 1 1 1 Ureidoglycolate hydrolase ADH_zinc_N PF00107.21 EEQ77947.1 - 7.3e-08 32.0 0.1 1.3e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEQ77947.1 - 5.5e-05 22.8 0.1 0.00011 21.9 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Tim17 PF02466.14 EEQ77948.1 - 8.8e-25 87.2 0.8 2.1e-24 86.0 0.4 1.6 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family HTH_33 PF13592.1 EEQ77949.1 - 0.00018 21.0 0.2 0.00037 19.9 0.0 1.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 EEQ77949.1 - 0.0011 19.0 0.0 0.0027 17.7 0.0 1.7 1 1 0 1 1 1 1 Transposase HTH_32 PF13565.1 EEQ77949.1 - 0.0014 19.4 0.0 0.0037 18.0 0.0 1.8 1 1 1 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EEQ77949.1 - 0.0022 17.9 0.1 0.012 15.5 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.1 EEQ77949.1 - 0.0032 17.6 0.0 0.008 16.3 0.0 1.7 1 1 1 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EEQ77949.1 - 0.064 12.9 1.1 0.26 11.0 0.1 2.2 2 0 0 2 2 2 0 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EEQ77949.1 - 0.07 12.5 0.2 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 Brix PF04427.13 EEQ77950.1 - 4.7e-31 107.9 0.0 6.4e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain RNase_P_p30 PF01876.11 EEQ77952.1 - 1.1e-51 173.9 0.0 1.5e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 CDC45 PF02724.9 EEQ77952.1 - 0.074 11.0 0.3 0.098 10.6 0.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.20 EEQ77953.1 - 5.7e-58 196.1 0.0 6.6e-58 195.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ77953.1 - 8.4e-19 67.6 0.0 1.2e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ77953.1 - 2.3e-07 30.7 0.2 0.00017 21.4 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ77953.1 - 0.011 15.2 0.1 0.033 13.7 0.0 1.8 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EEQ77953.1 - 0.055 12.8 0.1 0.099 11.9 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 EEQ77953.1 - 0.066 12.2 0.1 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEQ77953.1 - 0.069 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Aconitase_B_N PF11791.3 EEQ77953.1 - 0.12 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Aconitate B N-terminal domain tRNA-synt_1 PF00133.17 EEQ77954.1 - 1.2e-213 710.5 0.2 6e-213 708.1 0.1 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EEQ77954.1 - 8.9e-35 119.6 1.3 1.9e-34 118.6 0.9 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EEQ77954.1 - 5.4e-15 54.9 2.6 7e-07 28.2 0.0 5.3 4 2 1 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EEQ77954.1 - 1.1e-08 34.6 3.2 2e-05 24.0 0.0 3.1 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 EEQ77954.1 - 0.016 14.0 0.0 1.2 7.8 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 EEQ77954.1 - 0.016 14.3 0.0 0.15 11.1 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Caenor_Her-1 PF09232.5 EEQ77956.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Caenorhabditis elegans Her-1 DUF2413 PF10310.4 EEQ77956.1 - 2.5 6.8 10.7 0.095 11.4 2.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) DUF3431 PF11913.3 EEQ77959.1 - 1.7e-87 292.5 0.2 2.2e-87 292.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF3243 PF11588.3 EEQ77959.1 - 0.63 10.0 5.1 2.9 7.9 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3243) zf-rbx1 PF12678.2 EEQ77961.1 - 7.4e-12 45.2 0.7 1.4e-11 44.2 0.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EEQ77961.1 - 3.7e-09 36.2 7.4 3.7e-08 33.0 5.2 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EEQ77961.1 - 1.5e-06 27.7 1.5 2.9e-06 26.8 1.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEQ77961.1 - 3.6e-06 26.5 2.8 2.3e-05 23.9 0.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEQ77961.1 - 4.9e-05 22.9 1.6 0.0002 21.0 1.3 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEQ77961.1 - 6.7e-05 22.8 1.5 6.7e-05 22.8 1.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEQ77961.1 - 0.0086 15.8 3.6 0.036 13.9 2.5 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EEQ77961.1 - 0.04 13.6 4.6 0.12 12.0 3.2 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 EEQ77961.1 - 1.2 8.7 3.3 0.64 9.6 0.7 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain MFS_1 PF07690.11 EEQ77962.1 - 4.8e-15 55.1 23.4 8.6e-10 37.8 5.5 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily ATP_transf PF09830.4 EEQ77964.1 - 3.1e-19 68.5 0.0 7.3e-19 67.3 0.0 1.7 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 EEQ77964.1 - 0.012 16.1 0.0 0.033 14.7 0.0 1.6 1 0 0 1 1 1 0 HIT domain SIC PF03482.8 EEQ77966.1 - 0.0065 16.1 0.5 0.0074 15.9 0.4 1.1 1 0 0 1 1 1 1 sic protein DUF605 PF04652.11 EEQ77968.1 - 5.1 6.3 17.2 5.1 6.3 11.9 1.0 1 0 0 1 1 1 0 Vta1 like Trypan_PARP PF05887.6 EEQ77968.1 - 8.7 6.1 14.1 11 5.8 9.7 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-C2H2 PF00096.21 EEQ77969.1 - 0.00071 19.7 21.2 0.93 9.9 0.0 5.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEQ77969.1 - 0.0085 16.3 22.8 0.11 12.8 0.0 5.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EEQ77969.1 - 0.025 14.5 0.8 0.38 10.7 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Menin PF05053.8 EEQ77969.1 - 0.38 8.8 4.8 0.61 8.1 3.4 1.2 1 0 0 1 1 1 0 Menin RPN7 PF10602.4 EEQ77970.1 - 1.2e-56 190.8 0.2 1.8e-56 190.2 0.1 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EEQ77970.1 - 7.4e-09 35.8 0.1 4.8e-08 33.2 0.0 2.5 2 1 0 2 2 2 1 PCI domain DSBA PF01323.15 EEQ77971.1 - 3.9e-18 65.7 0.0 4.4e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain DUF2874 PF11396.3 EEQ77971.1 - 0.026 14.4 0.2 0.66 9.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2874) adh_short PF00106.20 EEQ77972.1 - 1.4e-20 73.8 0.0 1.9e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ77972.1 - 7.8e-07 28.9 0.0 1.7e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEQ77972.1 - 5.6e-06 26.2 0.0 7.7e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EEQ77972.1 - 0.0022 18.0 0.1 0.0037 17.2 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EEQ77972.1 - 0.051 13.3 0.1 0.33 10.7 0.1 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase LtrA PF06772.6 EEQ77973.1 - 1.4e-12 47.1 20.3 1.4e-12 47.1 14.0 2.1 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) NTR2 PF15458.1 EEQ77974.1 - 2e-78 263.1 22.2 3.3e-78 262.4 15.4 1.4 1 0 0 1 1 1 1 Nineteen complex-related protein 2 Cyc-maltodext_N PF09087.6 EEQ77974.1 - 0.00082 19.2 0.1 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Cyclomaltodextrinase, N-terminal LSM PF01423.17 EEQ77975.1 - 2.4e-20 71.8 1.3 2.7e-20 71.6 0.9 1.0 1 0 0 1 1 1 1 LSM domain Peptidase_M1 PF01433.15 EEQ77976.1 - 8.9e-07 28.3 0.0 0.0069 15.5 0.0 3.3 3 0 0 3 3 3 3 Peptidase family M1 CDP-OH_P_transf PF01066.16 EEQ77977.1 - 9.8e-08 32.2 0.3 9.8e-08 32.2 0.2 2.8 4 1 0 4 4 4 1 CDP-alcohol phosphatidyltransferase APH PF01636.18 EEQ77978.1 - 3.9e-08 33.3 0.0 9.3e-08 32.0 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ77978.1 - 0.00064 19.3 0.0 0.0013 18.3 0.0 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EEQ77978.1 - 0.0084 15.2 0.0 0.019 14.1 0.0 1.5 2 0 0 2 2 2 1 Ecdysteroid kinase DUF3659 PF12396.3 EEQ77980.1 - 2e-16 59.3 0.5 5.3e-16 58.0 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3659) DUF3435 PF11917.3 EEQ77982.1 - 5.8e-57 193.2 1.6 8.6e-51 172.9 0.0 3.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) PX PF00787.19 EEQ77983.1 - 1.1e-14 54.1 0.0 2.1e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 PX domain SAS4 PF15460.1 EEQ77984.1 - 9.1e-20 70.4 1.6 9.1e-20 70.4 1.1 3.2 2 1 1 3 3 3 2 Something about silencing, SAS, complex subunit 4 DUF2457 PF10446.4 EEQ77984.1 - 1.8e-05 23.7 22.8 1.8e-05 23.7 15.8 3.6 2 1 2 4 4 4 1 Protein of unknown function (DUF2457) Daxx PF03344.10 EEQ77984.1 - 0.00022 19.9 21.1 0.00022 19.9 14.6 2.7 2 1 1 3 3 3 1 Daxx Family CobT PF06213.7 EEQ77984.1 - 0.71 8.9 28.3 1.4 7.9 19.6 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1510 PF07423.6 EEQ77984.1 - 5.6 6.2 31.6 0.4 10.0 15.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) RRN3 PF05327.6 EEQ77984.1 - 7.7 4.4 19.0 16 3.4 13.2 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3807 PF12720.2 EEQ77987.1 - 2.3e-44 151.5 5.6 2.8e-44 151.3 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) Motilin_ghrelin PF04644.7 EEQ77987.1 - 0.13 12.1 1.8 0.3 10.9 1.2 1.7 1 0 0 1 1 1 0 Motilin/ghrelin HVSL PF09749.4 EEQ77988.1 - 2.2e-81 272.3 0.0 2.7e-81 272.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein Pal1 PF08316.6 EEQ77991.1 - 2.6e-06 27.9 0.1 4e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Pal1 cell morphology protein MGC-24 PF05283.6 EEQ77991.1 - 5.7 6.6 6.9 8.7 6.0 4.8 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Ribosomal_S5 PF00333.15 EEQ77996.1 - 0.1 12.3 0.2 0.19 11.5 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain Myb_Cef PF11831.3 EEQ77999.1 - 0.02 14.1 12.5 0.023 13.9 8.7 1.2 1 0 0 1 1 1 0 pre-mRNA splicing factor component SR-25 PF10500.4 EEQ77999.1 - 0.031 13.7 19.7 0.035 13.5 13.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TTL PF03133.10 EEQ77999.1 - 0.04 12.8 3.0 0.05 12.5 2.1 1.2 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family Vfa1 PF08432.5 EEQ77999.1 - 0.056 13.4 15.1 0.065 13.2 10.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SET PF00856.23 EEQ77999.1 - 0.069 13.4 3.5 0.081 13.2 2.4 1.1 1 0 0 1 1 1 0 SET domain NST1 PF13945.1 EEQ77999.1 - 0.069 13.2 13.4 0.085 12.9 9.3 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator MIP-T3 PF10243.4 EEQ77999.1 - 0.093 11.1 24.9 0.11 10.9 17.2 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Rtf2 PF04641.7 EEQ77999.1 - 0.24 10.5 15.1 0.26 10.4 10.5 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger DUF913 PF06025.7 EEQ77999.1 - 0.26 10.0 3.1 0.32 9.6 2.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GAGA_bind PF06217.7 EEQ77999.1 - 0.38 10.6 11.4 0.4 10.6 7.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family FAM60A PF15396.1 EEQ77999.1 - 0.4 10.3 9.5 0.45 10.2 6.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PLRV_ORF5 PF01690.12 EEQ77999.1 - 0.44 9.6 8.7 0.51 9.4 6.0 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Glyco_transf_15 PF01793.11 EEQ77999.1 - 0.56 9.0 10.1 0.68 8.8 7.0 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase YqfQ PF14181.1 EEQ77999.1 - 0.58 10.1 16.4 0.3 11.1 10.0 1.5 2 0 0 2 2 2 0 YqfQ-like protein RR_TM4-6 PF06459.7 EEQ77999.1 - 0.72 9.7 15.9 0.93 9.3 11.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDRGK PF09756.4 EEQ77999.1 - 0.81 9.0 19.0 0.96 8.8 13.2 1.2 1 0 0 1 1 1 0 DDRGK domain TATR PF03430.8 EEQ77999.1 - 0.87 8.1 10.3 0.96 8.0 7.2 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Ycf1 PF05758.7 EEQ77999.1 - 1.2 6.7 10.3 1.2 6.7 7.2 1.0 1 0 0 1 1 1 0 Ycf1 RNA_polI_A34 PF08208.6 EEQ77999.1 - 1.5 8.4 30.7 2.5 7.7 21.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF2894 PF11445.3 EEQ77999.1 - 1.6 8.9 7.1 1.8 8.7 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) DUF4603 PF15376.1 EEQ77999.1 - 1.7 5.7 10.0 1.8 5.6 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Borrelia_P83 PF05262.6 EEQ77999.1 - 2.3 6.3 16.2 2.6 6.2 11.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Afi1 PF07792.7 EEQ77999.1 - 2.7 7.9 8.9 3.6 7.5 6.1 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking ELL PF10390.4 EEQ77999.1 - 2.9 7.0 13.4 3.4 6.8 9.3 1.1 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL DUF2413 PF10310.4 EEQ77999.1 - 3.3 6.4 14.5 3.7 6.2 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) HSP70 PF00012.15 EEQ77999.1 - 5.8 4.7 13.7 6.7 4.4 9.5 1.0 1 0 0 1 1 1 0 Hsp70 protein Med19 PF10278.4 EEQ77999.1 - 6.2 6.4 23.0 8.8 5.9 15.9 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF3464 PF11947.3 EEQ77999.1 - 6.5 6.2 12.9 8 5.9 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DDHD PF02862.12 EEQ77999.1 - 6.9 6.4 10.3 9.4 5.9 7.1 1.2 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.11 EEQ77999.1 - 7.3 6.4 6.9 8.5 6.1 4.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Erp_C PF06780.6 EEQ78001.1 - 0.32 10.8 2.2 0.33 10.7 1.5 1.1 1 0 0 1 1 1 0 Erp protein C-terminus Histone PF00125.19 EEQ78002.1 - 6e-10 39.1 0.0 1.1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 UPF0233 PF06781.7 EEQ78004.1 - 3.6 7.2 6.6 4.3 7.0 0.3 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) KH_1 PF00013.24 EEQ78006.1 - 4.5e-81 266.4 17.3 5.1e-12 45.2 0.1 13.3 13 2 0 13 13 13 9 KH domain KH_3 PF13014.1 EEQ78006.1 - 3.2e-60 198.9 21.4 4.2e-11 42.2 0.7 12.8 12 1 0 12 12 12 10 KH domain KH_2 PF07650.12 EEQ78006.1 - 9.3e-14 50.7 14.1 0.0039 16.7 0.3 6.7 5 1 1 6 6 6 4 KH domain SLS PF14611.1 EEQ78006.1 - 6.8e-10 38.7 0.3 0.32 10.3 0.0 7.5 4 2 3 7 7 7 2 Mitochondrial inner-membrane-bound regulator BMC PF00936.14 EEQ78006.1 - 0.0089 15.6 0.9 19 5.0 0.1 4.9 6 0 0 6 6 6 1 BMC domain DUF1664 PF07889.7 EEQ78006.1 - 0.048 13.4 0.1 0.19 11.5 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Pkinase PF00069.20 EEQ78007.1 - 8.9e-42 143.0 0.1 6.5e-21 74.6 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ78007.1 - 5.6e-25 87.8 0.1 3.4e-13 49.2 0.1 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase PBD PF00786.23 EEQ78007.1 - 4.8e-20 71.7 1.8 1.5e-19 70.1 0.1 2.9 2 0 0 2 2 2 1 P21-Rho-binding domain VHS PF00790.14 EEQ78008.1 - 9.2e-36 122.5 0.9 1.7e-35 121.7 0.6 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 EEQ78008.1 - 5.6e-18 64.0 1.2 1e-16 59.9 0.0 2.6 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.1 EEQ78008.1 - 2e-16 59.3 0.2 6.1e-16 57.7 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EEQ78008.1 - 8e-14 50.8 0.1 2.8e-13 49.1 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain UIM PF02809.15 EEQ78008.1 - 0.014 14.8 1.3 0.048 13.2 0.9 2.0 1 0 0 1 1 1 0 Ubiquitin interaction motif UCH_1 PF13423.1 EEQ78009.1 - 4.2e-77 259.4 0.2 5.7e-77 259.0 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EEQ78009.1 - 6.1e-19 68.8 0.0 5.1e-17 62.6 0.0 2.5 2 0 0 2 2 2 1 Exonuclease UCH PF00443.24 EEQ78009.1 - 2.1e-06 27.0 0.1 3.7e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-CHY PF05495.7 EEQ78009.1 - 0.16 12.1 0.9 2 8.6 0.0 2.5 2 0 0 2 2 2 0 CHY zinc finger 2-Hacid_dh_C PF02826.14 EEQ78010.1 - 1.4e-52 177.4 0.0 2.9e-52 176.3 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEQ78010.1 - 4.2e-37 126.5 0.0 5.6e-36 122.9 0.0 2.5 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.1 EEQ78010.1 - 0.027 14.7 0.0 0.087 13.1 0.0 1.9 1 0 0 1 1 1 0 XdhC Rossmann domain DUF770 PF05591.7 EEQ78010.1 - 0.14 11.6 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF770) Fe-ADH PF00465.14 EEQ78011.1 - 3e-101 338.6 0.0 3.8e-101 338.3 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EEQ78011.1 - 3.2e-15 56.1 0.0 2.1e-11 43.6 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 EEQ78011.1 - 0.00042 19.7 0.0 0.00067 19.1 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Glyoxalase PF00903.20 EEQ78012.1 - 8.5e-37 125.9 0.0 3.4e-19 69.0 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EEQ78012.1 - 4.4e-31 107.6 0.0 6.5e-17 62.1 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EEQ78012.1 - 9.1e-15 54.6 0.0 2.5e-06 27.4 0.0 3.6 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EEQ78012.1 - 6.3e-05 22.9 0.0 0.0045 16.9 0.0 3.1 3 1 0 3 3 3 1 Glyoxalase-like domain CppA_C PF14507.1 EEQ78012.1 - 0.061 13.5 0.1 0.77 9.9 0.0 2.2 2 0 0 2 2 2 0 CppA C-terminal CppA_N PF14506.1 EEQ78012.1 - 0.14 11.8 0.1 0.57 9.8 0.0 1.9 2 0 0 2 2 2 0 CppA N-terminal MxiH PF09392.5 EEQ78014.1 - 0.048 14.2 0.0 1.1 9.8 0.0 2.7 1 1 0 1 1 1 0 Type III secretion needle MxiH like Arrestin_C PF02752.17 EEQ78015.1 - 7e-18 65.0 0.1 1.7e-17 63.7 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EEQ78015.1 - 2.8e-13 49.9 0.0 9.3e-13 48.2 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EEQ78015.1 - 0.00064 19.2 0.0 0.015 14.7 0.0 2.7 4 0 0 4 4 4 1 Arrestin_N terminal like Cauli_DNA-bind PF03310.8 EEQ78016.1 - 0.025 14.4 1.3 0.04 13.7 0.8 1.4 1 1 0 1 1 1 0 Caulimovirus DNA-binding protein APH PF01636.18 EEQ78017.1 - 3e-11 43.5 0.0 5.7e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EEQ78017.1 - 0.016 14.3 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 EEQ78017.1 - 0.032 13.8 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase WD40 PF00400.27 EEQ78018.1 - 1.9e-21 75.1 16.2 2e-06 27.4 0.2 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 EEQ78018.1 - 6.2e-05 22.8 0.0 0.0045 16.7 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EEQ78018.1 - 0.0011 17.3 0.0 0.0019 16.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain IKI3 PF04762.7 EEQ78018.1 - 0.0029 15.5 0.0 0.026 12.3 0.0 1.8 1 1 0 2 2 2 1 IKI3 family DUF1273 PF06908.6 EEQ78018.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) Miro PF08477.8 EEQ78019.1 - 3.2e-37 127.6 0.0 5.4e-19 68.8 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 EEQ78019.1 - 1.2e-32 111.5 0.0 2.1e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 EEQ78019.1 - 3.4e-30 103.1 0.1 5.8e-30 102.3 0.1 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 EEQ78019.1 - 3.8e-24 84.9 0.0 6.4e-13 48.4 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 EEQ78019.1 - 2.3e-10 40.4 0.0 0.00047 20.1 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.1 EEQ78019.1 - 5.6e-06 26.3 2.3 0.00021 21.3 0.4 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EEQ78019.1 - 2.1e-05 23.4 0.6 0.034 13.4 0.0 3.3 3 0 0 3 3 3 1 EF hand AAA_16 PF13191.1 EEQ78019.1 - 5.7e-05 23.1 0.9 0.26 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.18 EEQ78019.1 - 0.00013 21.8 0.9 0.37 10.5 0.2 3.4 3 1 1 4 4 4 2 Dynamin family AAA_29 PF13555.1 EEQ78019.1 - 0.00014 21.3 0.2 0.079 12.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain EF-hand_6 PF13405.1 EEQ78019.1 - 0.00052 19.6 1.4 0.018 14.8 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain AAA_22 PF13401.1 EEQ78019.1 - 0.0007 19.7 0.2 0.87 9.7 0.0 3.1 2 1 1 3 3 3 1 AAA domain GTP_EFTU PF00009.22 EEQ78019.1 - 0.0029 17.0 0.0 5 6.5 0.0 3.2 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_28 PF13521.1 EEQ78019.1 - 0.0038 17.2 0.0 1.8 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EEQ78019.1 - 0.0046 16.6 0.1 0.27 10.9 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B EF-hand_8 PF13833.1 EEQ78019.1 - 0.0064 16.0 0.4 0.13 11.8 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair AAA_25 PF13481.1 EEQ78019.1 - 0.0076 15.6 0.1 2.8 7.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain EF-hand_5 PF13202.1 EEQ78019.1 - 0.014 14.6 1.3 0.49 9.8 0.0 2.8 2 0 0 2 2 2 0 EF hand AAA_24 PF13479.1 EEQ78019.1 - 0.02 14.5 0.0 0.1 12.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EEQ78019.1 - 0.044 13.6 0.0 9.9 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain EF-hand_10 PF14788.1 EEQ78019.1 - 0.059 13.0 0.5 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 EF hand AAA_18 PF13238.1 EEQ78019.1 - 0.061 13.6 0.2 11 6.3 0.1 2.8 2 2 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EEQ78019.1 - 0.078 13.1 0.0 0.81 9.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 EEQ78019.1 - 0.11 11.9 0.1 17 4.8 0.1 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EEQ78019.1 - 0.12 13.1 0.0 16 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EEQ78019.1 - 0.15 11.4 0.0 12 5.1 0.0 2.6 2 1 1 3 3 3 0 AAA-like domain ABC_tran PF00005.22 EEQ78019.1 - 0.19 12.0 0.0 9.7 6.4 0.0 2.4 2 0 0 2 2 2 0 ABC transporter DUF500 PF04366.7 EEQ78020.1 - 2.6e-45 152.9 0.3 5.2e-45 151.9 0.1 1.5 2 0 0 2 2 2 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EEQ78020.1 - 3.5e-14 51.8 0.5 1e-13 50.4 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EEQ78020.1 - 1.4e-11 43.7 0.1 2.8e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EEQ78020.1 - 3.3e-11 42.4 0.0 9.1e-11 41.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Spectrin PF00435.16 EEQ78021.1 - 0.043 14.1 0.5 0.43 10.8 0.2 1.9 1 1 1 2 2 2 0 Spectrin repeat TrbM PF07424.6 EEQ78021.1 - 0.1 12.5 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 TrbM Zds_C PF08632.5 EEQ78022.1 - 6.2e-27 92.7 0.2 1.1e-26 91.9 0.1 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Synaptobrevin PF00957.16 EEQ78023.1 - 0.031 13.8 1.7 0.84 9.2 0.1 2.2 1 1 1 2 2 2 0 Synaptobrevin ArfGap PF01412.13 EEQ78024.1 - 1.6e-35 121.3 0.3 2.5e-35 120.7 0.2 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SelR PF01641.13 EEQ78026.1 - 3.5e-50 168.8 0.1 4.1e-50 168.6 0.0 1.0 1 0 0 1 1 1 1 SelR domain DUF2296 PF10058.4 EEQ78026.1 - 0.0032 17.1 0.9 1.1 9.0 0.0 2.2 2 0 0 2 2 2 2 Predicted integral membrane metal-binding protein (DUF2296) DZR PF12773.2 EEQ78026.1 - 0.0056 16.4 3.7 0.45 10.3 0.2 2.4 2 1 0 2 2 2 2 Double zinc ribbon NOB1_Zn_bind PF08772.6 EEQ78026.1 - 0.0095 15.7 0.8 0.32 10.8 0.1 2.3 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like GFA PF04828.9 EEQ78026.1 - 0.021 14.7 0.6 2 8.3 0.0 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Yippee-Mis18 PF03226.9 EEQ78026.1 - 0.038 14.0 0.4 0.14 12.2 0.3 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn_ribbon_recom PF13408.1 EEQ78026.1 - 0.22 11.8 3.4 6.3 7.1 0.2 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Smr PF01713.16 EEQ78027.1 - 1.2e-10 41.3 0.1 1.2e-10 41.3 0.1 2.3 3 0 0 3 3 3 1 Smr domain DUF1771 PF08590.5 EEQ78027.1 - 2.6e-07 30.5 6.4 2.6e-07 30.5 4.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) CUE PF02845.11 EEQ78027.1 - 7.9e-06 25.2 0.0 1.7e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 CUE domain Pkinase_Tyr PF07714.12 EEQ78028.1 - 4.9e-08 32.3 0.0 1.7e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EEQ78028.1 - 5.6e-08 32.2 0.0 8.2e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EEQ78028.1 - 0.0085 15.0 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Resistin PF06954.6 EEQ78028.1 - 0.034 14.4 1.6 2.8 8.2 0.6 2.5 2 0 0 2 2 2 0 Resistin APH PF01636.18 EEQ78028.1 - 0.11 12.2 0.3 0.19 11.4 0.2 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Meiotic_rec114 PF03525.9 EEQ78030.1 - 2.2e-05 23.1 0.2 0.0021 16.6 0.0 2.7 2 1 1 3 3 3 2 Meiotic recombination protein rec114 Zn_clus PF00172.13 EEQ78031.1 - 2.5e-10 40.0 10.6 3.9e-10 39.4 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAF1_ABF1 PF04684.8 EEQ78031.1 - 0.23 10.2 19.2 0.35 9.6 13.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Suf PF05843.9 EEQ78031.1 - 1.1 8.9 11.8 2.5 7.7 8.2 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ATAD4 PF15321.1 EEQ78031.1 - 3.8 8.5 7.4 13 6.9 5.1 2.0 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 Paramyxo_ncap PF00973.14 EEQ78031.1 - 4 6.0 6.1 6.1 5.4 4.2 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein TPR_20 PF14561.1 EEQ78032.1 - 0.022 14.8 1.8 0.045 13.8 0.7 1.8 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF2120 PF09893.4 EEQ78032.1 - 0.26 11.2 2.9 0.29 11.0 2.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) HPHLAWLY PF14925.1 EEQ78033.1 - 0.048 11.6 0.7 0.053 11.5 0.5 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF2072 PF09845.4 EEQ78033.1 - 0.14 12.0 0.8 0.18 11.7 0.5 1.1 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) EBV-NA3 PF05009.7 EEQ78034.1 - 0.096 11.9 1.9 0.11 11.7 1.3 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CAF-1_p60_C PF15512.1 EEQ78034.1 - 0.12 12.7 7.8 0.14 12.6 5.4 1.1 1 0 0 1 1 1 0 Chromatin assembly factor complex 1 subunit p60, C-terminal Neugrin PF06413.6 EEQ78034.1 - 2.9 7.6 8.2 3.3 7.4 5.7 1.0 1 0 0 1 1 1 0 Neugrin Senescence_reg PF04520.8 EEQ78034.1 - 6.3 7.2 8.4 7.7 6.9 5.8 1.0 1 0 0 1 1 1 0 Senescence regulator Pkinase PF00069.20 EEQ78035.1 - 0.00025 20.2 0.0 0.00056 19.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EEQ78035.1 - 0.00029 20.6 0.0 0.00029 20.6 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ78035.1 - 0.0024 16.9 0.0 0.0041 16.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HSDR_N_2 PF13588.1 EEQ78035.1 - 0.0074 16.0 0.0 0.93 9.3 0.0 2.5 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) DUF4302 PF14135.1 EEQ78036.1 - 0.014 14.8 0.7 0.017 14.5 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4302) Cluap1 PF10234.4 EEQ78036.1 - 0.014 14.5 0.8 0.017 14.3 0.6 1.0 1 0 0 1 1 1 0 Clusterin-associated protein-1 Tcell_CD4_Cterm PF12104.3 EEQ78038.1 - 0.16 11.6 1.0 0.16 11.6 0.7 3.1 3 0 0 3 3 3 0 T cell CD4 receptor C terminal region Copper-fist PF00649.13 EEQ78042.1 - 2.4e-22 77.8 1.6 2.4e-22 77.8 1.1 2.7 2 1 1 3 3 3 1 Copper fist DNA binding domain PEX11 PF05648.9 EEQ78043.1 - 2.4e-74 249.3 0.5 2.7e-74 249.1 0.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Sugar_tr PF00083.19 EEQ78044.1 - 4.5e-26 91.4 32.2 2e-16 59.6 5.9 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EEQ78044.1 - 3.8e-14 52.1 39.7 3.8e-14 52.1 27.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Aminotran_1_2 PF00155.16 EEQ78045.1 - 2.1e-43 148.6 0.0 2.9e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RPN7 PF10602.4 EEQ78046.1 - 4.2e-54 182.5 0.4 6.6e-54 181.9 0.3 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EEQ78046.1 - 8.5e-13 48.5 0.0 1.8e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.1 EEQ78046.1 - 0.0073 16.0 0.1 0.045 13.5 0.1 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ78046.1 - 0.027 15.0 0.6 0.17 12.6 0.4 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3100 PF11299.3 EEQ78046.1 - 0.077 12.2 0.2 0.15 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3100) PEPCK_ATP PF01293.15 EEQ78048.1 - 8.7e-217 720.1 0.0 1e-216 719.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 EEQ78048.1 - 0.097 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EEQ78048.1 - 0.11 11.9 0.0 0.79 9.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EEQ78048.1 - 0.14 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 EEQ78048.1 - 0.16 12.2 0.0 22 5.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain IBR PF01485.16 EEQ78049.1 - 1.2e-10 41.0 27.6 1.9e-07 30.8 4.6 4.7 4 1 0 4 4 4 3 IBR domain zf-RING_2 PF13639.1 EEQ78049.1 - 0.017 14.9 6.1 0.017 14.9 4.2 4.6 3 2 1 4 4 4 0 Ring finger domain BTAD PF03704.12 EEQ78049.1 - 0.16 12.2 4.2 0.35 11.1 2.8 1.7 1 1 0 1 1 1 0 Bacterial transcriptional activator domain DUF830 PF05708.7 EEQ78049.1 - 1.8 8.5 4.0 2.1 8.3 0.1 2.2 2 0 0 2 2 2 0 Orthopoxvirus protein of unknown function (DUF830) Mito_carr PF00153.22 EEQ78051.1 - 4.9e-48 160.8 0.6 1.7e-20 72.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3611 PF12263.3 EEQ78051.1 - 0.025 13.9 0.1 0.041 13.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) zf-Nse PF11789.3 EEQ78053.1 - 4.5e-21 74.1 2.3 7.8e-21 73.3 1.6 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 EEQ78053.1 - 0.0013 18.5 1.0 0.0021 17.8 0.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EEQ78053.1 - 0.0043 16.7 0.5 0.008 15.8 0.1 1.7 1 1 0 1 1 1 1 RING-type zinc-finger FtsK_SpoIIIE PF01580.13 EEQ78053.1 - 0.0068 15.8 3.2 0.012 15.0 2.2 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF2828 PF11443.3 EEQ78053.1 - 0.02 13.1 1.0 0.028 12.6 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) zf-MIZ PF02891.15 EEQ78053.1 - 0.046 13.2 6.5 0.28 10.7 4.5 2.2 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger MscS_porin PF12795.2 EEQ78053.1 - 0.68 9.2 9.6 0.021 14.1 1.5 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Pox_MCEL PF03291.11 EEQ78054.1 - 1.2e-59 201.9 0.0 2.3e-56 191.0 0.0 3.6 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_12 PF08242.7 EEQ78054.1 - 2.5e-08 34.3 0.0 1.8e-07 31.5 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ78054.1 - 2.8e-08 34.3 0.0 6.5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ78054.1 - 3.3e-07 30.6 0.0 0.034 14.6 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ78054.1 - 1.7e-05 24.6 0.0 3.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ78054.1 - 2.9e-05 24.3 0.0 0.00018 21.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ78054.1 - 5.8e-05 22.7 0.0 0.0036 16.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EEQ78054.1 - 0.0002 20.4 0.0 0.00034 19.6 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family zf-C3HC PF07967.8 EEQ78055.1 - 2.2e-37 127.8 0.0 2e-34 118.2 0.0 2.9 3 0 0 3 3 3 2 C3HC zinc finger-like Rsm1 PF08600.5 EEQ78055.1 - 3.9e-32 109.9 0.1 2e-29 101.2 0.0 2.9 3 0 0 3 3 3 2 Rsm1-like zf-CHY PF05495.7 EEQ78056.1 - 1.4e-18 66.8 22.6 5.5e-18 64.8 9.2 3.3 3 0 0 3 3 3 2 CHY zinc finger priB_priC PF07445.7 EEQ78056.1 - 0.078 12.4 0.6 5.8 6.3 0.3 2.3 2 0 0 2 2 2 0 Primosomal replication protein priB and priC DZR PF12773.2 EEQ78056.1 - 1.4 8.8 14.6 12 5.8 0.1 3.7 3 0 0 3 3 3 0 Double zinc ribbon DUF3295 PF11702.3 EEQ78058.1 - 1.2e-156 522.7 35.2 1.4e-156 522.4 24.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 EEQ78058.1 - 5.4e-06 25.8 5.5 1.3e-05 24.6 3.8 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) LtrA PF06772.6 EEQ78060.1 - 1.5e-21 76.7 17.9 1.5e-21 76.7 12.4 2.1 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) Cpn60_TCP1 PF00118.19 EEQ78062.1 - 1.4e-147 492.2 3.0 1.6e-147 492.0 2.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CPT PF07931.7 EEQ78062.1 - 0.038 13.6 0.5 3.1 7.3 0.0 3.0 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Chromo_shadow PF01393.14 EEQ78063.1 - 1.4e-13 50.4 0.2 1.1e-11 44.3 0.1 2.4 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.19 EEQ78063.1 - 1.3e-10 40.8 0.6 2.6e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain MRI PF15325.1 EEQ78063.1 - 0.82 10.6 8.1 9.5 7.2 0.3 2.3 2 0 0 2 2 2 0 Modulator of retrovirus infection Rap1_C PF11626.3 EEQ78064.1 - 1.2e-24 85.9 0.0 4.3e-23 80.9 0.0 2.4 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 EEQ78064.1 - 1.3e-18 66.5 0.4 1.3e-18 66.5 0.3 2.5 3 0 0 3 3 3 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 EEQ78064.1 - 4.5e-08 33.5 1.1 3.2e-07 30.8 0.0 2.5 2 0 0 2 2 2 1 Rap1, DNA-binding Myb_DNA-binding PF00249.26 EEQ78064.1 - 0.075 13.0 2.3 14 5.7 0.1 3.5 3 0 0 3 3 3 0 Myb-like DNA-binding domain zf-DHHC PF01529.15 EEQ78065.1 - 4.9e-33 113.9 10.2 1.2e-32 112.7 7.1 1.9 1 1 0 1 1 1 1 DHHC palmitoyltransferase Sec7 PF01369.15 EEQ78067.1 - 1.7e-56 190.9 0.0 2.6e-56 190.2 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EEQ78067.1 - 4e-15 55.6 0.0 1.7e-08 34.0 0.0 2.8 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal RhoGEF PF00621.15 EEQ78068.1 - 2.8e-22 79.4 0.0 7.2e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.3 EEQ78068.1 - 3.1e-08 33.3 0.0 6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Ank_2 PF12796.2 EEQ78069.1 - 1e-28 99.5 4.0 2.7e-10 40.4 0.2 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EEQ78069.1 - 1.1e-23 80.8 2.9 5.7e-05 22.9 0.1 6.2 5 1 1 6 6 6 4 Ankyrin repeat Ank PF00023.25 EEQ78069.1 - 5.4e-23 79.6 6.1 6.1e-05 22.6 0.2 6.5 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 EEQ78069.1 - 8.9e-22 77.0 2.7 2e-07 31.3 0.1 5.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ78069.1 - 6.9e-15 54.7 4.5 8.9e-05 22.6 0.0 5.1 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEQ78070.1 - 2.1e-22 79.2 13.9 4.7e-10 39.6 0.7 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEQ78070.1 - 3.7e-17 61.1 11.4 0.00022 20.8 0.0 6.8 7 1 1 8 8 8 4 Ankyrin repeat Ank_3 PF13606.1 EEQ78070.1 - 1.2e-13 49.7 1.8 0.0025 17.8 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EEQ78070.1 - 2.7e-12 46.8 1.3 0.0045 17.4 0.0 4.2 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEQ78070.1 - 2.8e-12 46.4 5.1 0.0015 18.6 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeats (many copies) ATP_bind_3 PF01171.15 EEQ78072.1 - 3.2e-34 118.0 0.0 8.2e-26 90.6 0.0 2.2 2 0 0 2 2 2 2 PP-loop family Mito_carr PF00153.22 EEQ78073.1 - 5.2e-47 157.5 1.1 1.1e-19 69.8 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3943 PF13084.1 EEQ78073.1 - 0.028 13.9 0.1 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3943) Cupin_5 PF06172.6 EEQ78074.1 - 7.3e-20 71.2 0.0 1.6e-19 70.2 0.0 1.5 1 1 0 1 1 1 1 Cupin superfamily (DUF985) DUF3337 PF11816.3 EEQ78075.1 - 4.4e-94 315.5 0.1 9.2e-89 298.0 0.9 3.3 2 1 0 3 3 3 2 Domain of unknown function (DUF3337) WD40 PF00400.27 EEQ78075.1 - 7.8e-30 101.6 16.3 1.4e-08 34.3 0.1 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat Pkinase PF00069.20 EEQ78076.1 - 2e-55 187.7 0.0 1.6e-54 184.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ78076.1 - 3.3e-19 68.9 0.0 5.9e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ78076.1 - 0.023 14.4 0.1 0.062 13.0 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L11_N PF03946.9 EEQ78077.1 - 3e-26 90.6 0.1 9.6e-26 89.0 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EEQ78077.1 - 7.4e-24 83.6 0.6 1.1e-23 83.1 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Svf1 PF08622.5 EEQ78078.1 - 9.3e-126 419.2 0.0 1.2e-125 418.7 0.0 1.2 1 0 0 1 1 1 1 Svf1-like CrtC PF07143.6 EEQ78078.1 - 0.0096 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) Molybdopterin PF00384.17 EEQ78080.1 - 1.2e-19 70.4 0.0 1.7e-11 43.4 0.0 3.2 3 0 0 3 3 3 2 Molybdopterin oxidoreductase Molydop_binding PF01568.16 EEQ78080.1 - 5e-08 32.7 0.0 1.2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain HNH_2 PF13391.1 EEQ78081.1 - 0.001 18.8 0.2 0.0026 17.5 0.2 1.8 1 1 0 1 1 1 1 HNH endonuclease NTP_transf_3 PF12804.2 EEQ78082.1 - 5.6e-07 29.7 0.1 7.8e-07 29.2 0.1 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain MoeA_N PF03453.12 EEQ78083.1 - 3.3e-06 26.5 0.0 4.3e-05 22.9 0.0 2.4 1 1 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.19 EEQ78083.1 - 0.02 14.2 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Probable molybdopterin binding domain SR-25 PF10500.4 EEQ78083.1 - 1.5 8.2 11.2 0.07 12.5 4.0 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Acetyltransf_1 PF00583.19 EEQ78084.1 - 1.3e-05 25.0 0.0 3.3e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EEQ78084.1 - 0.016 15.3 0.5 2.9 8.0 0.1 2.5 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EEQ78084.1 - 0.044 13.5 0.4 0.1 12.3 0.2 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_7 PF13508.1 EEQ78084.1 - 0.12 12.5 0.0 2 8.6 0.0 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Pho86 PF11124.3 EEQ78084.1 - 0.15 11.0 1.6 0.2 10.6 0.3 1.7 1 1 1 2 2 2 0 Inorganic phosphate transporter Pho86 DHC_N1 PF08385.7 EEQ78085.1 - 3.2e-182 606.9 11.8 3.2e-182 606.9 8.2 4.0 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EEQ78085.1 - 7.9e-130 433.0 4.6 7.9e-130 433.0 3.2 3.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 EEQ78085.1 - 1.2e-99 334.3 0.1 2.6e-98 329.8 0.0 3.0 2 1 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 EEQ78085.1 - 8e-77 257.8 0.0 2e-76 256.5 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 EEQ78085.1 - 2e-43 147.8 0.1 9.8e-43 145.6 0.1 2.3 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 EEQ78085.1 - 1.2e-42 145.7 0.2 1.2e-41 142.4 0.2 2.3 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 EEQ78085.1 - 1.1e-39 136.1 6.1 2.2e-39 135.1 4.2 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EEQ78085.1 - 1.2e-32 112.5 1.4 9.5e-11 41.5 0.0 6.9 6 1 0 6 6 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EEQ78085.1 - 1e-19 70.6 0.0 1e-18 67.4 0.0 2.7 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 EEQ78085.1 - 1.4e-15 57.5 0.7 0.0071 16.4 0.0 6.7 7 0 0 7 7 6 4 AAA domain AAA PF00004.24 EEQ78085.1 - 4e-14 52.9 0.0 0.00047 20.3 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EEQ78085.1 - 3.2e-10 40.0 0.1 0.26 11.1 0.0 5.2 4 0 0 4 4 4 3 AAA domain AAA_17 PF13207.1 EEQ78085.1 - 1.6e-09 38.6 0.0 0.033 15.0 0.0 5.8 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.1 EEQ78085.1 - 7.4e-09 35.9 0.1 0.028 14.7 0.0 5.4 4 0 0 4 4 4 2 AAA domain T2SE PF00437.15 EEQ78085.1 - 1.9e-06 27.0 0.0 0.077 11.8 0.0 4.3 5 0 0 5 5 5 2 Type II/IV secretion system protein AAA_29 PF13555.1 EEQ78085.1 - 3e-05 23.4 0.0 2 7.9 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_19 PF13245.1 EEQ78085.1 - 6.2e-05 22.6 0.2 0.9 9.3 0.0 4.5 4 0 0 4 4 4 1 Part of AAA domain Mg_chelatase PF01078.16 EEQ78085.1 - 9e-05 21.7 0.8 0.51 9.4 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EEQ78085.1 - 0.00011 21.3 1.3 0.96 8.5 0.0 4.2 4 0 0 4 4 3 2 Zeta toxin ABC_tran PF00005.22 EEQ78085.1 - 0.00013 22.2 3.2 2.2 8.5 0.0 5.1 4 0 0 4 4 3 2 ABC transporter AAA_16 PF13191.1 EEQ78085.1 - 0.00029 20.8 18.7 0.11 12.4 0.1 8.1 8 1 2 10 10 9 1 AAA ATPase domain ERM PF00769.14 EEQ78085.1 - 0.012 15.2 19.7 0.64 9.5 9.0 3.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family RNA_helicase PF00910.17 EEQ78085.1 - 0.015 15.5 0.1 39 4.4 0.0 4.5 4 0 0 4 4 4 0 RNA helicase MobB PF03205.9 EEQ78085.1 - 0.03 14.0 0.3 12 5.5 0.0 3.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EEQ78085.1 - 1.2 8.4 11.2 0.51 9.7 0.0 5.0 7 0 0 7 7 6 0 AAA domain AAA_10 PF12846.2 EEQ78085.1 - 9.4 5.5 14.4 9.4 5.5 0.1 5.1 6 0 0 6 6 6 0 AAA-like domain Ribonuclease_3 PF00636.21 EEQ78086.1 - 2.4e-45 153.6 0.0 5.8e-22 78.2 0.0 3.0 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EEQ78086.1 - 1.6e-28 99.2 0.0 3.2e-15 56.2 0.0 3.6 3 1 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.9 EEQ78086.1 - 4e-17 61.7 0.0 2.3e-15 56.1 0.0 3.2 3 0 0 3 3 3 1 Dicer dimerisation domain Helicase_C PF00271.26 EEQ78086.1 - 8.4e-15 54.4 0.0 2.3e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ78086.1 - 1.4e-12 47.8 0.9 2.9e-12 46.7 0.6 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EEQ78086.1 - 3.4e-10 39.6 0.1 6.1e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.20 EEQ78086.1 - 5.6e-05 23.6 0.0 0.028 14.9 0.1 3.5 3 0 0 3 3 3 1 Double-stranded RNA binding motif SNF2_N PF00176.18 EEQ78086.1 - 0.022 13.5 0.1 0.043 12.6 0.1 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF2075 PF09848.4 EEQ78086.1 - 0.042 12.8 0.0 0.11 11.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TAP42 PF04177.7 EEQ78087.1 - 1.4e-106 356.2 0.8 1.8e-106 355.9 0.5 1.0 1 0 0 1 1 1 1 TAP42-like family DUF4477 PF14780.1 EEQ78087.1 - 0.11 11.8 0.7 0.18 11.1 0.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) Lipase_GDSL_2 PF13472.1 EEQ78088.1 - 1e-15 58.3 0.0 3.7e-15 56.4 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EEQ78088.1 - 1.5e-10 41.3 0.0 2.3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Luciferase_cat PF10285.4 EEQ78088.1 - 0.18 10.9 0.2 3.3 6.7 0.0 2.5 2 1 1 3 3 3 0 Luciferase catalytic domain Porphobil_deam PF01379.15 EEQ78089.1 - 2.3e-73 245.6 0.0 3.5e-73 245.0 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EEQ78089.1 - 8.8e-19 67.3 0.4 1.6e-18 66.5 0.3 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Adenosine_kin PF04008.9 EEQ78089.1 - 0.42 10.0 1.7 2.1 7.8 0.2 2.3 2 0 0 2 2 2 0 Adenosine specific kinase Lon_C PF05362.8 EEQ78090.1 - 1.1e-70 237.1 0.3 2.8e-70 235.8 0.2 1.7 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 EEQ78090.1 - 1.3e-24 86.9 0.0 7.1e-24 84.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 EEQ78090.1 - 6.7e-24 84.7 0.7 1.3e-23 83.7 0.0 1.8 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain ChlI PF13541.1 EEQ78090.1 - 2e-08 33.7 0.0 1.2e-07 31.3 0.0 2.2 2 1 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 EEQ78090.1 - 2.2e-08 33.9 0.0 8.8e-08 31.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EEQ78090.1 - 1.9e-06 28.0 0.0 6.8e-06 26.1 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.8 EEQ78090.1 - 7.3e-06 24.9 0.0 3.8e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 EEQ78090.1 - 1.5e-05 25.7 0.1 6.8e-05 23.6 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EEQ78090.1 - 4.5e-05 23.1 0.0 0.00012 21.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EEQ78090.1 - 7.9e-05 22.1 0.0 0.00022 20.7 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.6 EEQ78090.1 - 0.00018 21.1 0.0 0.00047 19.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EEQ78090.1 - 0.00019 20.5 0.0 0.0018 17.3 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EEQ78090.1 - 0.00062 19.6 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEQ78090.1 - 0.00078 19.5 0.6 0.0038 17.3 0.0 2.6 2 1 0 2 2 1 1 AAA domain Birna_VP4 PF01768.11 EEQ78090.1 - 0.00086 18.4 0.0 0.0016 17.5 0.0 1.5 1 0 0 1 1 1 1 Birnavirus VP4 protein AAA_2 PF07724.9 EEQ78090.1 - 0.00093 19.1 0.0 0.0041 17.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 EEQ78090.1 - 0.0034 16.4 0.0 0.0068 15.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 EEQ78090.1 - 0.0041 16.5 0.0 0.0088 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEQ78090.1 - 0.0055 16.6 0.0 0.016 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EEQ78090.1 - 0.0057 16.2 0.5 0.014 14.9 0.2 1.8 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.1 EEQ78090.1 - 0.0068 16.0 0.7 0.12 11.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.1 EEQ78090.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EEQ78090.1 - 0.016 14.3 0.1 0.041 13.0 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EEQ78090.1 - 0.02 14.1 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_10 PF12846.2 EEQ78090.1 - 0.024 14.0 0.2 0.64 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 EEQ78090.1 - 0.024 14.9 0.1 0.1 12.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EEQ78090.1 - 0.026 14.6 0.0 0.074 13.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 EEQ78090.1 - 0.028 13.3 0.0 0.065 12.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 EEQ78090.1 - 0.03 13.9 0.0 0.077 12.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.1 EEQ78090.1 - 0.034 14.4 0.0 0.034 14.4 0.0 2.9 1 1 1 2 2 1 0 AAA domain UPF0079 PF02367.12 EEQ78090.1 - 0.046 13.3 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 EEQ78090.1 - 0.071 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_PrkA PF08298.6 EEQ78090.1 - 0.082 11.5 0.1 0.55 8.8 0.0 2.0 1 1 0 2 2 2 0 PrkA AAA domain AAA_28 PF13521.1 EEQ78090.1 - 0.12 12.3 0.1 0.33 10.8 0.1 1.8 1 0 0 1 1 1 0 AAA domain CCDC-167 PF15188.1 EEQ78090.1 - 9.1 6.3 7.6 1.8 8.5 0.7 2.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Ribosomal_L23 PF00276.15 EEQ78091.1 - 2.1e-16 59.6 0.0 4e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 RIO1 PF01163.17 EEQ78092.1 - 1.6e-43 148.2 0.0 2.4e-30 105.3 0.0 2.2 2 0 0 2 2 2 2 RIO1 family APH PF01636.18 EEQ78092.1 - 3.6e-08 33.4 0.1 3.5e-05 23.6 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EEQ78092.1 - 2.5e-07 29.9 0.0 1.4e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Rio2_N PF09202.6 EEQ78092.1 - 2.9e-05 24.0 0.2 5.5e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Rio2, N-terminal NOA36 PF06524.7 EEQ78092.1 - 3.6 6.7 8.8 5.3 6.1 6.1 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 EEQ78092.1 - 4.6 5.0 10.3 6 4.6 7.1 1.1 1 0 0 1 1 1 0 Nop14-like family PC_rep PF01851.17 EEQ78093.1 - 3e-16 58.6 16.6 0.00016 21.7 0.1 8.8 9 0 0 9 9 9 5 Proteasome/cyclosome repeat DUF106 PF01956.11 EEQ78093.1 - 0.068 12.7 0.1 6.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Integral membrane protein DUF106 DNA_mis_repair PF01119.14 EEQ78095.1 - 1.9e-34 117.6 0.0 3.9e-34 116.6 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EEQ78095.1 - 1.8e-15 56.8 0.0 4.2e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EEQ78095.1 - 7.9e-10 38.4 0.0 1.9e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DSPc PF00782.15 EEQ78096.1 - 1.2e-27 96.1 0.0 1.5e-19 69.8 0.0 2.5 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EEQ78096.1 - 5.7e-06 25.8 0.0 7.1e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EEQ78096.1 - 0.025 14.6 0.3 0.057 13.4 0.1 1.6 2 0 0 2 2 2 0 Inositol hexakisphosphate PALP PF00291.20 EEQ78098.1 - 1.6e-06 27.6 0.1 8.2e-05 21.9 0.1 2.1 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme Relaxase PF03432.9 EEQ78098.1 - 0.033 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain Phlebovirus_G1 PF07243.6 EEQ78098.1 - 0.15 10.1 0.1 0.21 9.7 0.1 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 Collagen PF01391.13 EEQ78099.1 - 0.12 11.9 12.5 0.24 10.9 8.6 1.5 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) TFIIA PF03153.8 EEQ78099.1 - 0.18 11.6 7.9 0.2 11.5 5.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4187 PF13821.1 EEQ78100.1 - 4.6e-19 67.7 3.5 1.3e-18 66.2 2.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EEQ78100.1 - 4.2e-09 36.0 0.2 1.1e-06 28.3 0.1 2.5 2 0 0 2 2 2 2 G-patch domain Voldacs PF03517.8 EEQ78100.1 - 0.11 12.3 6.8 3.3 7.5 0.0 3.0 3 0 0 3 3 3 0 Regulator of volume decrease after cellular swelling MRP-S31 PF15433.1 EEQ78100.1 - 1.9 7.8 18.4 0.25 10.7 7.6 2.1 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 SWIRM PF04433.12 EEQ78101.1 - 0.086 12.9 0.1 0.17 12.0 0.1 1.5 1 1 0 1 1 1 0 SWIRM domain zf-B_box PF00643.19 EEQ78102.1 - 9.4 6.2 10.6 21 5.1 7.4 1.5 1 0 0 1 1 1 0 B-box zinc finger CPSase_L_D2 PF02786.12 EEQ78105.1 - 1.3e-107 357.8 0.0 1.9e-84 282.1 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EEQ78105.1 - 2.1e-41 140.5 0.0 4.7e-41 139.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EEQ78105.1 - 8.9e-37 125.5 0.0 1.2e-17 63.9 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EEQ78105.1 - 6.8e-36 123.7 0.1 2.7e-19 69.6 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EEQ78105.1 - 2.2e-23 82.5 0.0 1.2e-08 34.0 0.0 4.0 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EEQ78105.1 - 9.7e-20 70.6 0.1 1.9e-09 37.1 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EEQ78105.1 - 9.9e-17 60.9 0.8 1.5e-07 31.0 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EEQ78105.1 - 6.7e-09 35.4 0.0 0.00019 20.9 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.14 EEQ78105.1 - 1.7e-05 24.4 0.2 0.14 11.6 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 EEQ78105.1 - 3.3e-05 23.2 0.0 0.025 13.7 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 EEQ78105.1 - 0.022 14.6 0.0 0.068 13.0 0.0 1.9 1 0 0 1 1 1 0 MGS-like domain Epimerase PF01370.16 EEQ78105.1 - 0.069 12.5 0.0 2.7 7.3 0.0 2.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family SET PF00856.23 EEQ78106.1 - 2e-14 54.1 0.1 4.2e-14 53.1 0.1 1.6 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.13 EEQ78106.1 - 1.6e-09 37.4 8.6 1.6e-09 37.4 6.0 2.0 2 0 0 2 2 2 1 MYND finger Gp-FAR-1 PF05823.7 EEQ78106.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) SPT2 PF08243.6 EEQ78107.1 - 5.7e-08 33.0 11.6 1.9e-07 31.3 8.0 1.9 1 0 0 1 1 1 1 SPT2 chromatin protein TMEM52 PF14979.1 EEQ78107.1 - 0.25 11.2 2.0 0.5 10.2 1.4 1.5 1 0 0 1 1 1 0 Transmembrane 52 Ribosomal_60s PF00428.14 EEQ78108.1 - 1.1e-27 96.2 13.6 1.3e-27 96.0 9.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_S19 PF00203.16 EEQ78109.1 - 2e-34 117.0 0.3 2.8e-34 116.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 SbcD_C PF12320.3 EEQ78109.1 - 0.038 14.0 0.1 0.29 11.1 0.0 1.9 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Carb_kinase PF01256.12 EEQ78110.1 - 3.4e-43 147.6 0.0 4.4e-42 144.0 0.0 2.0 2 0 0 2 2 2 1 Carbohydrate kinase zf-C2H2_4 PF13894.1 EEQ78111.1 - 5.8e-06 26.2 27.2 0.18 12.2 0.2 7.2 6 1 1 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ78111.1 - 4.1e-05 23.6 26.5 0.27 11.6 0.2 6.8 6 0 0 6 6 6 2 Zinc finger, C2H2 type PAT1 PF09770.4 EEQ78111.1 - 0.034 12.3 20.9 0.051 11.8 14.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-C2H2_jaz PF12171.3 EEQ78111.1 - 0.13 12.4 4.6 1.9 8.7 0.1 4.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Suf PF05843.9 EEQ78111.1 - 0.15 11.7 8.2 0.36 10.5 5.7 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Serinc PF03348.10 EEQ78111.1 - 0.64 8.6 1.9 0.92 8.1 1.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Folate_carrier PF01770.13 EEQ78111.1 - 0.96 7.8 1.3 1.4 7.3 0.9 1.1 1 0 0 1 1 1 0 Reduced folate carrier Band_3_cyto PF07565.8 EEQ78111.1 - 2.3 7.6 6.4 4.9 6.5 4.4 1.5 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4175 PF13779.1 EEQ78111.1 - 3.9 5.0 26.9 6.3 4.3 18.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4407 PF14362.1 EEQ78111.1 - 8.7 5.1 9.7 14 4.4 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C2H2 PF00096.21 EEQ78113.1 - 2.6 8.5 32.2 0.57 10.6 0.3 5.5 5 0 0 5 5 5 0 Zinc finger, C2H2 type DUF4098 PF13345.1 EEQ78115.1 - 1.5e-06 28.0 5.9 0.0065 16.4 0.9 3.8 3 1 1 4 4 4 3 Domain of unknown function (DUF4098) Spc7 PF08317.6 EEQ78115.1 - 0.0015 17.2 143.5 0.0015 17.2 10.5 6.2 1 1 5 6 6 6 4 Spc7 kinetochore protein TPR_MLP1_2 PF07926.7 EEQ78115.1 - 0.0022 17.7 32.8 0.0022 17.7 22.8 8.8 2 1 6 9 9 9 3 TPR/MLP1/MLP2-like protein Filament PF00038.16 EEQ78115.1 - 0.0039 16.6 60.6 0.0039 16.6 42.0 4.8 2 1 1 4 4 4 3 Intermediate filament protein DUF4200 PF13863.1 EEQ78115.1 - 0.0082 16.0 18.7 0.0082 16.0 13.0 9.8 2 1 7 9 9 9 6 Domain of unknown function (DUF4200) Atg14 PF10186.4 EEQ78115.1 - 0.49 9.2 132.1 0.035 13.0 14.7 6.7 1 1 6 7 7 7 0 UV radiation resistance protein and autophagy-related subunit 14 Reo_sigmaC PF04582.7 EEQ78115.1 - 0.9 8.6 42.0 0.34 10.0 0.6 5.1 1 1 4 5 5 5 0 Reovirus sigma C capsid protein DUF713 PF05218.9 EEQ78118.1 - 0.044 13.5 0.3 0.044 13.5 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF713) Myb_DNA-bind_6 PF13921.1 EEQ78120.1 - 0.0002 21.4 1.6 0.00054 20.0 1.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEQ78120.1 - 0.0029 17.6 3.0 0.0083 16.1 2.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain UPF0102 PF02021.12 EEQ78121.1 - 0.08 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0102 Pkinase PF00069.20 EEQ78121.1 - 0.1 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain CK_II_beta PF01214.13 EEQ78122.1 - 2.8e-77 258.3 0.0 5.9e-77 257.3 0.0 1.5 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 EEQ78122.1 - 0.0077 16.8 5.7 0.0077 16.8 3.9 2.3 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Mito_fiss_reg PF05308.6 EEQ78122.1 - 0.058 12.7 0.6 0.11 11.8 0.4 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Myc_N PF01056.13 EEQ78122.1 - 3.6 6.6 7.5 0.56 9.3 1.3 2.1 3 0 0 3 3 3 0 Myc amino-terminal region RRN3 PF05327.6 EEQ78122.1 - 6.2 4.8 5.6 0.29 9.1 0.3 1.3 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 bZIP_1 PF00170.16 EEQ78124.1 - 6.2e-05 22.8 8.4 0.00012 21.9 5.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEQ78124.1 - 0.00038 20.2 6.0 0.0008 19.1 4.1 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EEQ78124.1 - 0.21 11.9 12.2 0.061 13.6 5.8 1.8 1 1 1 2 2 2 0 bZIP Maf transcription factor Striatin PF08232.7 EEQ78124.1 - 1.2 9.4 7.6 1.8 8.8 5.3 1.3 1 0 0 1 1 1 0 Striatin family Aminotran_4 PF01063.14 EEQ78125.1 - 9.5e-31 107.0 0.0 1.2e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Pkinase PF00069.20 EEQ78126.1 - 8.6e-15 54.5 0.0 1.9e-14 53.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ78126.1 - 3.4e-08 32.8 0.0 1.4e-07 30.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Peptidase_M49 PF03571.10 EEQ78127.1 - 4.9e-234 777.5 0.0 5.7e-234 777.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Glucosamine_iso PF01182.15 EEQ78127.1 - 0.035 13.8 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase SNF5 PF04855.7 EEQ78129.1 - 2.3e-88 295.7 0.0 3.1e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 WD40 PF00400.27 EEQ78132.1 - 4.6e-51 168.9 24.9 2.9e-13 49.1 0.3 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EEQ78132.1 - 2.7e-06 27.1 13.6 0.0058 16.3 1.0 3.8 2 2 0 4 4 4 2 Transcription factor IIIC subunit delta N-term Zip PF02535.17 EEQ78133.1 - 0.037 13.0 2.5 0.047 12.7 1.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 EEQ78133.1 - 0.34 10.2 6.4 0.49 9.7 4.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region F-box-like PF12937.2 EEQ78134.1 - 0.00027 20.6 0.0 0.00054 19.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like ABC_tran PF00005.22 EEQ78136.1 - 8.6e-49 165.3 0.1 7e-23 81.4 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 EEQ78136.1 - 2.3e-20 72.2 6.3 2.3e-20 72.2 4.3 3.1 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.1 EEQ78136.1 - 6.2e-17 62.4 0.2 0.0012 18.8 0.0 4.6 5 0 0 5 5 4 3 AAA domain SMC_N PF02463.14 EEQ78136.1 - 1.1e-10 41.1 2.2 0.013 14.7 0.0 4.6 5 0 0 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EEQ78136.1 - 9.4e-09 36.1 0.1 0.0099 16.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 EEQ78136.1 - 1.4e-06 28.4 0.2 0.0026 17.7 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 EEQ78136.1 - 2.3e-06 28.0 0.0 0.017 15.5 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 EEQ78136.1 - 5.4e-06 25.6 0.0 0.055 12.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EEQ78136.1 - 7e-06 25.4 0.7 0.077 12.5 0.1 2.9 2 1 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 EEQ78136.1 - 9.1e-06 24.9 5.7 0.65 8.9 0.0 4.8 4 2 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.1 EEQ78136.1 - 2.2e-05 24.5 0.0 0.27 11.3 0.0 3.2 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EEQ78136.1 - 2.3e-05 24.3 0.0 0.1 12.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 EEQ78136.1 - 2.6e-05 24.5 1.9 0.38 11.0 0.0 3.7 5 0 0 5 5 2 2 AAA domain MobB PF03205.9 EEQ78136.1 - 5.4e-05 22.9 0.1 0.19 11.4 0.1 2.9 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EEQ78136.1 - 5.4e-05 23.2 2.0 0.036 14.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EEQ78136.1 - 5.6e-05 23.0 0.0 0.2 11.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EEQ78136.1 - 0.0004 20.0 0.1 0.6 9.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_10 PF12846.2 EEQ78136.1 - 0.00045 19.7 0.0 1.6 8.1 0.0 3.6 3 0 0 3 3 3 1 AAA-like domain AAA_23 PF13476.1 EEQ78136.1 - 0.00089 19.6 17.2 0.041 14.2 0.0 4.7 5 0 0 5 5 5 2 AAA domain AAA PF00004.24 EEQ78136.1 - 0.00096 19.3 0.0 0.75 10.0 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 EEQ78136.1 - 0.0011 17.8 0.2 1 8.0 0.0 2.5 2 0 0 2 2 2 2 ArgK protein AAA_14 PF13173.1 EEQ78136.1 - 0.0019 18.1 0.0 2 8.2 0.0 3.1 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 EEQ78136.1 - 0.003 16.6 0.0 0.33 10.0 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin NTPase_1 PF03266.10 EEQ78136.1 - 0.005 16.5 0.1 0.96 9.1 0.0 2.8 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.17 EEQ78136.1 - 0.0053 16.9 0.0 2.8 8.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 EEQ78136.1 - 0.0069 15.7 0.0 3.7 6.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EEQ78136.1 - 0.0071 16.2 0.3 3 7.8 0.1 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 EEQ78136.1 - 0.0093 15.4 0.0 1.2 8.5 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.18 EEQ78136.1 - 0.027 14.2 11.8 0.45 10.3 0.0 4.2 4 1 1 5 5 4 0 Dynamin family AAA_24 PF13479.1 EEQ78136.1 - 0.03 13.9 0.1 5.2 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EEQ78136.1 - 0.033 13.0 0.0 5.1 5.8 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.14 EEQ78136.1 - 0.035 13.5 2.0 1.2 8.5 0.2 2.8 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EEQ78136.1 - 0.065 12.9 0.3 7.3 6.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EEQ78136.1 - 0.12 11.8 0.1 18 4.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 EEQ78136.1 - 1.2 8.9 0.0 1.2 8.9 0.0 4.3 6 0 0 6 6 4 0 Domain of unknown function DUF87 Sugar_tr PF00083.19 EEQ78137.1 - 1.1e-111 373.6 9.8 1.4e-111 373.2 6.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEQ78137.1 - 9.8e-31 106.7 21.8 9.8e-31 106.7 15.1 2.3 1 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEQ78137.1 - 7.7e-05 21.0 2.9 0.00013 20.2 2.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LacY_symp PF01306.14 EEQ78137.1 - 0.00037 19.1 3.8 0.0017 16.9 0.4 2.3 2 0 0 2 2 2 2 LacY proton/sugar symporter MFS_1 PF07690.11 EEQ78138.1 - 1.5e-28 99.5 25.1 1.5e-28 99.5 17.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ78138.1 - 0.00011 20.9 1.5 0.00011 20.9 1.1 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter SKG6 PF08693.5 EEQ78141.1 - 0.0075 15.5 1.5 0.014 14.6 1.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Ank_2 PF12796.2 EEQ78142.1 - 1.4e-39 134.2 6.2 1.1e-10 41.6 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEQ78142.1 - 1.1e-27 95.8 6.7 9.1e-12 45.1 0.0 5.7 2 1 5 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.25 EEQ78142.1 - 3e-23 80.4 11.6 2.5e-05 23.8 0.0 8.1 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 EEQ78142.1 - 1.2e-17 63.5 6.1 5.3e-05 23.3 0.0 6.3 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ78142.1 - 7.7e-15 53.5 10.0 0.0022 18.0 0.0 8.2 8 0 0 8 8 8 3 Ankyrin repeat GDPD PF03009.12 EEQ78142.1 - 3.9e-14 52.7 0.0 8.1e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SPX PF03105.14 EEQ78142.1 - 2.3e-06 27.5 0.9 3.9e-06 26.8 0.6 1.2 1 0 0 1 1 1 1 SPX domain Dimerisation PF08100.6 EEQ78142.1 - 0.0068 16.2 0.0 2.5 7.9 0.0 2.7 2 0 0 2 2 2 2 Dimerisation domain DUF1279 PF06916.8 EEQ78143.1 - 4.7e-29 100.5 0.0 1.1e-28 99.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1279) DUF3446 PF11928.3 EEQ78143.1 - 0.065 13.4 6.5 0.15 12.2 4.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) SR-25 PF10500.4 EEQ78143.1 - 0.14 11.6 12.2 0.19 11.1 8.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RE_Eco29kI PF09517.5 EEQ78143.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Eco29kI restriction endonuclease Ribosomal_L3 PF00297.17 EEQ78144.1 - 2.4e-39 135.3 5.9 7.3e-38 130.4 4.1 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 Coa1 PF08695.5 EEQ78145.1 - 6.7e-41 138.4 0.0 8.4e-41 138.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Enkurin PF13864.1 EEQ78146.1 - 0.03 14.5 0.7 0.048 13.8 0.5 1.2 1 0 0 1 1 1 0 Calmodulin-binding DUF1673 PF07895.6 EEQ78146.1 - 0.16 11.4 1.0 0.56 9.7 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1673) JmjC PF02373.17 EEQ78147.1 - 4.5e-08 33.3 0.5 9.9e-07 29.0 0.4 2.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 EEQ78147.1 - 8.4e-08 32.3 7.7 8.4e-08 32.3 5.3 2.4 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 EEQ78147.1 - 0.027 13.9 0.0 0.064 12.7 0.0 1.5 1 0 0 1 1 1 0 Cupin domain UbiA PF01040.13 EEQ78148.1 - 6.7e-32 110.7 18.1 9e-32 110.2 12.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Glutaredoxin PF00462.19 EEQ78149.1 - 2.3e-16 59.5 0.0 4.2e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin DUF4288 PF14119.1 EEQ78149.1 - 0.053 13.6 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) HOASN PF14515.1 EEQ78150.1 - 0.0085 16.4 0.2 0.023 15.0 0.0 1.9 1 1 1 2 2 2 1 Haem-oxygenase-associated N-terminal helices DUF1664 PF07889.7 EEQ78150.1 - 0.13 12.0 2.8 1.4 8.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CTP_transf_2 PF01467.21 EEQ78151.1 - 1.3e-16 61.0 0.0 9.1e-14 51.8 0.0 2.7 2 1 0 2 2 2 2 Cytidylyltransferase PRELI PF04707.9 EEQ78154.1 - 5.2e-45 152.8 0.3 6e-45 152.6 0.2 1.0 1 0 0 1 1 1 1 PRELI-like family Mpp10 PF04006.7 EEQ78155.1 - 1.2e-84 284.8 47.0 1.5e-82 277.9 32.6 2.2 1 1 0 1 1 1 1 Mpp10 protein Methyltransf_16 PF10294.4 EEQ78156.1 - 1.1e-46 158.4 0.0 1.5e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EEQ78156.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 EEQ78156.1 - 0.061 13.9 0.0 0.088 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PC4 PF02229.11 EEQ78157.1 - 3.8e-21 74.0 0.0 5.9e-21 73.4 0.0 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) C-term_anchor PF13461.1 EEQ78157.1 - 1.4 9.4 3.5 3.6 8.1 0.2 2.4 3 0 0 3 3 3 0 Cell-wall surface anchor repeat Hydantoinase_B PF02538.9 EEQ78158.1 - 1.2e-201 670.5 0.0 1.7e-201 670.0 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EEQ78158.1 - 4.9e-94 314.6 0.0 9.4e-94 313.7 0.0 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EEQ78158.1 - 1.7e-57 193.7 0.1 9.8e-56 188.0 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Peptidase_M24 PF00557.19 EEQ78160.1 - 5.1e-51 173.2 0.0 8.5e-51 172.4 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EEQ78160.1 - 8.2e-27 93.2 0.0 6.7e-26 90.2 0.0 2.3 3 0 0 3 3 3 1 Aminopeptidase P, N-terminal domain Nexin_C PF08628.7 EEQ78161.1 - 1.1e-19 70.6 0.0 3e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 Sorting nexin C terminal PXA PF02194.10 EEQ78161.1 - 5.3e-08 32.6 1.3 0.007 15.9 0.6 3.7 1 1 1 2 2 2 2 PXA domain PX PF00787.19 EEQ78161.1 - 5.3e-08 32.6 0.2 1.3e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 PX domain Acyl_transf_1 PF00698.16 EEQ78162.1 - 7.3e-22 78.1 0.1 2e-18 66.7 0.0 2.0 1 1 0 1 1 1 1 Acyl transferase domain CI-B14_5a PF07347.7 EEQ78163.1 - 0.011 15.4 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) DUF1761 PF08570.5 EEQ78164.1 - 3.6e-24 85.1 1.9 4e-24 85.0 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) PhaG_MnhG_YufB PF03334.9 EEQ78164.1 - 0.34 10.9 2.9 2.3 8.3 2.0 2.6 1 1 0 1 1 1 0 Na+/H+ antiporter subunit DDHD PF02862.12 EEQ78165.1 - 1.3e-68 231.2 0.2 1.3e-68 231.2 0.1 2.9 2 2 0 2 2 2 1 DDHD domain CH PF00307.26 EEQ78166.1 - 1.3e-63 211.8 0.0 3.2e-19 68.9 0.4 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 EEQ78166.1 - 1e-06 28.7 0.5 2.4e-05 24.3 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.3 EEQ78166.1 - 0.00037 20.0 0.0 1.5 8.5 0.0 3.6 3 0 0 3 3 3 1 CAMSAP CH domain EF-hand_1 PF00036.27 EEQ78166.1 - 0.0038 16.4 0.7 0.96 8.9 0.1 3.5 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 EEQ78166.1 - 0.03 14.1 2.6 0.27 11.2 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain RRM_1 PF00076.17 EEQ78167.1 - 3.3e-12 45.8 0.0 4.5e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ78167.1 - 2.9e-07 30.3 0.0 4.7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ78167.1 - 3.1e-07 30.1 0.0 4.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEQ78167.1 - 0.002 17.8 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Mito_carr PF00153.22 EEQ78168.1 - 3.7e-78 257.3 1.1 3.5e-26 90.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L18e PF00828.14 EEQ78169.1 - 4.9e-26 91.6 0.1 7.4e-26 91.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Aldedh PF00171.17 EEQ78170.1 - 3.5e-11 42.1 2.3 4.5e-09 35.1 0.7 2.5 2 1 0 2 2 2 2 Aldehyde dehydrogenase family AA_permease PF00324.16 EEQ78172.1 - 7.8e-104 347.6 42.7 8.9e-104 347.4 29.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEQ78172.1 - 1.4e-30 106.2 47.0 1.7e-30 105.9 32.6 1.0 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.3 EEQ78173.1 - 3.3e-60 203.7 3.4 3.9e-60 203.4 2.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ78173.1 - 0.00014 21.6 8.0 0.00027 20.7 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PALP PF00291.20 EEQ78174.1 - 5.5e-23 81.6 0.0 2.1e-17 63.3 0.1 2.2 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.23 EEQ78174.1 - 2e-18 66.6 0.3 4.4e-18 65.4 0.2 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EEQ78174.1 - 0.0026 17.4 0.1 0.0061 16.2 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Creatinase_N PF01321.13 EEQ78175.1 - 3.6e-17 63.0 0.0 5.7e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.19 EEQ78175.1 - 1.2e-15 57.6 0.1 1.6e-15 57.2 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Aldedh PF00171.17 EEQ78176.1 - 4.4e-136 453.8 1.1 4.7e-135 450.5 0.7 1.9 1 1 0 1 1 1 1 Aldehyde dehydrogenase family DMRL_synthase PF00885.14 EEQ78176.1 - 0.075 12.7 0.1 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 6,7-dimethyl-8-ribityllumazine synthase Cu_amine_oxid PF01179.15 EEQ78177.1 - 1.6e-166 554.1 0.0 2.4e-166 553.5 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EEQ78177.1 - 3.1e-09 36.7 0.1 6.2e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EEQ78177.1 - 0.0037 17.3 0.0 0.0082 16.1 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain PCI PF01399.22 EEQ78178.1 - 0.00042 20.5 0.0 0.00096 19.4 0.0 1.6 1 0 0 1 1 1 1 PCI domain Apc3 PF12895.2 EEQ78178.1 - 0.015 15.4 0.1 0.14 12.3 0.0 2.5 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 NifU_N PF01592.11 EEQ78179.1 - 1.3e-51 173.8 0.0 1.7e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain MIT PF04212.13 EEQ78180.1 - 4.4e-09 36.0 0.9 9.5e-09 35.0 0.7 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_14 PF13173.1 EEQ78180.1 - 0.1 12.5 0.1 19 5.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF4398 PF14346.1 EEQ78180.1 - 5 7.2 8.3 0.71 9.9 0.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) Oxidored_q6 PF01058.17 EEQ78181.1 - 4e-22 78.2 0.0 5.7e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit RNase_H2-Ydr279 PF09468.5 EEQ78182.1 - 0.01 15.0 8.2 0.011 14.8 5.7 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DUF2313 PF10076.4 EEQ78182.1 - 0.073 12.4 0.3 0.073 12.4 0.2 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2313) SID-1_RNA_chan PF13965.1 EEQ78182.1 - 0.16 10.0 3.5 0.16 10.1 2.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ACP_syn_III PF08545.5 EEQ78184.1 - 3e-07 30.0 0.1 5.3e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EEQ78184.1 - 1.6e-05 24.0 0.0 2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EEQ78184.1 - 0.0017 17.9 0.1 0.0022 17.5 0.1 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.6 EEQ78184.1 - 0.016 13.6 0.1 0.02 13.3 0.1 1.1 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) DUF3208 PF11482.3 EEQ78184.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) ABC_tran PF00005.22 EEQ78185.1 - 0.0013 19.0 0.0 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter BRO1 PF03097.13 EEQ78186.1 - 1.3e-103 346.6 0.0 2.5e-103 345.7 0.0 1.5 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EEQ78186.1 - 1e-81 274.1 10.2 1.7e-81 273.4 7.1 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF605 PF04652.11 EEQ78186.1 - 0.052 12.9 21.9 0.076 12.3 15.2 1.2 1 0 0 1 1 1 0 Vta1 like bZIP_2 PF07716.10 EEQ78187.1 - 8.3e-13 47.9 13.3 1.5e-12 47.1 9.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EEQ78187.1 - 6.8e-06 25.9 11.3 1.1e-05 25.2 7.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor Herpes_BLRF2 PF05812.7 EEQ78187.1 - 0.0012 18.5 0.4 0.0026 17.5 0.1 1.7 1 1 0 1 1 1 1 Herpesvirus BLRF2 protein DUF4094 PF13334.1 EEQ78187.1 - 0.19 12.1 2.1 0.5 10.7 1.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Phlebovirus_NSM PF07246.6 EEQ78187.1 - 0.2 10.7 5.2 0.29 10.2 3.6 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M CENP-N PF05238.8 EEQ78189.1 - 8.1e-118 393.9 0.0 1.3e-117 393.2 0.0 1.3 1 1 0 1 1 1 1 Kinetochore protein CHL4 like zf-RING_2 PF13639.1 EEQ78190.1 - 2e-07 30.6 5.0 2e-07 30.6 3.5 1.7 2 0 0 2 2 2 1 Ring finger domain SWIM PF04434.12 EEQ78190.1 - 2.8e-05 23.4 0.2 5.4e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 SWIM zinc finger zf-Apc11 PF12861.2 EEQ78190.1 - 3e-05 23.7 1.7 3e-05 23.7 1.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EEQ78190.1 - 0.0022 18.0 4.3 0.0056 16.7 3.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_4 PF14570.1 EEQ78190.1 - 0.0037 16.8 5.6 0.0068 15.9 3.9 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EEQ78190.1 - 0.015 15.2 7.7 0.059 13.3 4.0 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_5 PF14634.1 EEQ78190.1 - 0.024 14.3 5.7 0.024 14.3 3.9 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EEQ78190.1 - 0.054 13.1 3.6 0.12 12.0 2.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEQ78190.1 - 0.14 12.2 6.9 0.32 11.0 4.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 EEQ78190.1 - 1.9 8.2 7.2 0.83 9.4 2.1 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF974 PF06159.8 EEQ78191.1 - 4.4e-75 252.3 0.0 7.9e-75 251.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF974) DENN PF02141.16 EEQ78192.1 - 4.1e-57 192.9 0.0 7.9e-57 191.9 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 EEQ78192.1 - 5.1e-19 68.0 0.3 1.1e-18 67.0 0.2 1.6 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 EEQ78192.1 - 5.3e-18 64.7 0.0 1.1e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 uDENN domain C1_2 PF03107.11 EEQ78192.1 - 0.00033 20.7 3.5 0.00056 19.9 2.4 1.4 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.17 EEQ78192.1 - 0.00064 19.4 6.1 0.001 18.7 4.3 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 EEQ78192.1 - 0.0013 18.6 3.4 0.0023 17.9 2.3 1.4 1 0 0 1 1 1 1 C1-like domain PHD PF00628.24 EEQ78192.1 - 0.011 15.4 3.6 0.024 14.3 2.5 1.6 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.1 EEQ78192.1 - 0.029 14.3 3.3 0.063 13.2 2.3 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain Prok-RING_1 PF14446.1 EEQ78192.1 - 0.04 13.6 4.5 0.07 12.8 3.1 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 EEQ78192.1 - 0.11 11.8 1.3 0.22 10.8 0.9 1.4 1 0 0 1 1 1 0 PHD-finger zf-HIT PF04438.11 EEQ78192.1 - 0.15 11.7 3.7 0.25 10.9 2.6 1.3 1 0 0 1 1 1 0 HIT zinc finger zf-HC5HC2H PF13771.1 EEQ78192.1 - 0.28 11.3 3.1 0.56 10.3 2.1 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_5 PF14634.1 EEQ78192.1 - 1.3 8.8 5.2 2.3 7.9 3.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain HATPase_c_3 PF13589.1 EEQ78193.1 - 2.8e-22 78.8 0.0 4.6e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 EEQ78193.1 - 3.7e-09 36.3 0.0 9.7e-08 31.7 0.0 2.8 2 1 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 EEQ78193.1 - 0.0011 18.6 0.0 0.0024 17.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4062 PF13271.1 EEQ78194.1 - 0.15 12.0 2.1 0.54 10.3 0.2 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4062) DUF2313 PF10076.4 EEQ78196.1 - 0.053 12.9 0.1 0.087 12.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2313) Ribosomal_S21 PF01165.15 EEQ78196.1 - 0.094 12.1 2.9 0.11 11.9 0.2 2.2 1 1 1 2 2 2 0 Ribosomal protein S21 RasGEF PF00617.14 EEQ78199.1 - 1.5e-51 174.7 0.1 2.6e-51 174.0 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EEQ78199.1 - 1.1e-17 63.9 0.0 3.1e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 EEQ78199.1 - 5.5e-06 25.8 0.0 1.3e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEQ78199.1 - 1.7e-05 24.0 0.0 5.6e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EEQ78199.1 - 0.053 13.0 0.0 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 Variant SH3 domain GHMP_kinases_N PF00288.21 EEQ78201.1 - 2.6e-14 53.0 0.0 5.1e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EEQ78201.1 - 0.00021 21.4 0.0 0.00045 20.3 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Med5 PF08689.5 EEQ78202.1 - 0 1012.1 0.0 0 1011.9 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 BCDHK_Adom3 PF10436.4 EEQ78202.1 - 0.14 11.6 0.1 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase ELFV_dehydrog PF00208.16 EEQ78205.1 - 6.8e-80 268.1 0.9 8.3e-80 267.8 0.6 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EEQ78205.1 - 2.1e-46 156.7 0.0 6e-46 155.2 0.0 1.8 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 EEQ78205.1 - 0.036 14.3 0.0 0.093 13.0 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding CFEM PF05730.6 EEQ78208.1 - 9.5e-07 28.5 6.4 1.7e-06 27.7 4.4 1.4 1 0 0 1 1 1 1 CFEM domain DUF4448 PF14610.1 EEQ78208.1 - 0.00068 19.1 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Plasmodium_Vir PF05795.6 EEQ78208.1 - 0.0044 16.2 0.0 0.0077 15.4 0.0 1.3 1 0 0 1 1 1 1 Plasmodium vivax Vir protein TMEM154 PF15102.1 EEQ78208.1 - 0.0094 15.6 10.4 0.061 13.0 7.2 2.2 1 1 0 1 1 1 1 TMEM154 protein family DUF912 PF06024.7 EEQ78208.1 - 0.025 14.6 0.0 0.065 13.2 0.0 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3377 PF11857.3 EEQ78208.1 - 0.061 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Spore_YpjB PF09577.5 EEQ78208.1 - 0.1 12.1 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) NTR2 PF15458.1 EEQ78208.1 - 0.11 11.7 3.4 0.18 10.9 2.3 1.3 1 0 0 1 1 1 0 Nineteen complex-related protein 2 DUF4366 PF14283.1 EEQ78208.1 - 0.12 11.7 0.1 0.49 9.7 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) APH PF01636.18 EEQ78210.1 - 2.1e-06 27.6 0.0 1.1e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EEQ78210.1 - 0.015 14.2 0.0 0.031 13.2 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase Ribonuc_red_lgC PF02867.10 EEQ78211.1 - 7.4e-215 714.5 0.0 1.2e-214 713.8 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EEQ78211.1 - 1.8e-24 85.2 0.0 4.2e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EEQ78211.1 - 1e-16 61.1 0.1 2.5e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain AAA_17 PF13207.1 EEQ78213.1 - 1.5e-05 25.7 0.1 6.3e-05 23.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEQ78213.1 - 4e-05 23.9 0.1 0.0023 18.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EEQ78213.1 - 0.00025 20.0 0.0 0.00042 19.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Zeta_toxin PF06414.7 EEQ78213.1 - 0.00041 19.5 0.3 0.0029 16.7 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.1 EEQ78213.1 - 0.00075 19.5 0.0 0.0015 18.5 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 EEQ78213.1 - 0.00089 18.1 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EEQ78213.1 - 0.0014 18.7 0.0 0.0036 17.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 EEQ78213.1 - 0.0021 17.6 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 EEQ78213.1 - 0.0036 17.1 0.0 0.22 11.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EEQ78213.1 - 0.0065 15.5 0.0 0.0066 15.4 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain AAA_28 PF13521.1 EEQ78213.1 - 0.0088 16.0 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EEQ78213.1 - 0.034 13.5 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.24 EEQ78213.1 - 0.036 14.2 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEQ78213.1 - 0.046 13.4 0.0 0.099 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EEQ78213.1 - 0.064 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 EEQ78213.1 - 0.089 11.7 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Thymidylate_kin PF02223.12 EEQ78213.1 - 0.093 12.0 0.0 0.75 9.1 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase cobW PF02492.14 EEQ78213.1 - 0.11 11.9 0.1 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain APS_kinase PF01583.15 EEQ78213.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_24 PF13479.1 EEQ78213.1 - 0.14 11.7 0.1 0.41 10.1 0.1 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EEQ78213.1 - 0.15 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Rsbr_N PF08678.5 EEQ78216.1 - 0.12 12.2 0.0 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 Rsbr N terminal Mor PF08765.6 EEQ78217.1 - 0.082 12.6 0.0 5.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Mor transcription activator family Sigma70_ner PF04546.8 EEQ78217.1 - 1.6 8.3 6.6 0.53 9.8 2.5 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region NOA36 PF06524.7 EEQ78217.1 - 1.9 7.6 6.6 3.3 6.8 4.6 1.3 1 0 0 1 1 1 0 NOA36 protein Mur_ligase_M PF08245.7 EEQ78218.1 - 4.4e-08 33.3 0.0 9e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Mur ligase middle domain Pkinase PF00069.20 EEQ78219.1 - 2.2e-62 210.5 0.5 1e-61 208.4 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ78219.1 - 6.4e-44 149.9 0.0 2e-43 148.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ78219.1 - 0.0061 15.5 0.0 0.019 13.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like HEAT_2 PF13646.1 EEQ78219.1 - 0.087 13.1 0.9 3.8 7.8 0.2 3.7 4 0 0 4 4 4 0 HEAT repeats ABC1 PF03109.11 EEQ78220.1 - 4e-33 113.9 0.0 8.2e-33 112.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 EEQ78220.1 - 0.0062 15.9 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Mito_carr PF00153.22 EEQ78221.1 - 1.1e-65 217.3 0.0 9.6e-23 79.7 0.0 3.5 2 2 1 3 3 3 3 Mitochondrial carrier protein UCR_14kD PF02271.11 EEQ78222.1 - 6.2e-43 144.8 4.3 1.6e-28 98.4 0.1 2.0 1 1 1 2 2 2 2 Ubiquinol-cytochrome C reductase complex 14kD subunit DNA_repr_REX1B PF14966.1 EEQ78222.1 - 0.043 14.2 0.5 0.06 13.7 0.3 1.2 1 0 0 1 1 1 0 DNA repair REX1-B DUF4541 PF15074.1 EEQ78222.1 - 0.063 13.8 2.3 0.68 10.5 0.1 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4541) HhH-GPD PF00730.20 EEQ78223.1 - 3.6e-15 56.1 0.6 1.7e-14 53.9 0.1 2.2 2 1 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein Ribosomal_60s PF00428.14 EEQ78223.1 - 6 7.3 13.8 1 9.8 6.2 2.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein Ecm33 PF12454.3 EEQ78225.1 - 4.8e-16 58.3 0.5 1.3e-15 56.9 0.3 1.8 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.19 EEQ78225.1 - 4.5e-10 39.4 0.2 0.01 15.7 0.0 4.4 1 1 3 4 4 4 3 Receptor L domain LRR_5 PF13306.1 EEQ78225.1 - 1.9e-05 24.3 0.8 0.024 14.3 0.1 2.5 1 1 0 2 2 2 2 Leucine rich repeats (6 copies) Anp1 PF03452.9 EEQ78226.1 - 2.7e-108 361.2 0.1 3.2e-108 360.9 0.0 1.1 1 0 0 1 1 1 1 Anp1 Ras PF00071.17 EEQ78227.1 - 8.4e-09 35.0 0.0 1.3e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEQ78227.1 - 0.023 15.2 0.0 0.038 14.4 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein Pyr_redox_2 PF07992.9 EEQ78229.1 - 2.3e-13 50.4 0.0 3.2e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEQ78229.1 - 5e-05 23.4 0.0 0.018 15.0 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EEQ78229.1 - 0.014 14.4 0.1 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.19 EEQ78229.1 - 0.016 14.0 0.2 0.14 10.9 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 EEQ78229.1 - 0.032 13.3 0.1 0.063 12.3 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EEQ78229.1 - 0.037 12.5 0.0 0.061 11.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein K_oxygenase PF13434.1 EEQ78229.1 - 0.052 12.4 0.0 1.6 7.5 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EEQ78229.1 - 0.2 11.4 0.5 1.1 8.9 0.2 2.2 2 1 0 2 2 2 0 FAD-NAD(P)-binding CAF-1_p150 PF11600.3 EEQ78230.1 - 0.047 13.0 20.3 0.093 12.0 14.1 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Borrelia_P83 PF05262.6 EEQ78230.1 - 0.41 8.8 7.1 0.56 8.4 4.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein His_Phos_1 PF00300.17 EEQ78231.1 - 4.8e-16 59.2 0.0 7.4e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HECT PF00632.20 EEQ78232.1 - 6.5e-75 252.2 0.0 1.1e-74 251.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-C2H2_2 PF12756.2 EEQ78233.1 - 3.2e-38 129.9 13.6 1.7e-29 101.8 4.3 3.3 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EEQ78233.1 - 1.1e-10 41.2 18.8 3.6e-06 26.9 1.4 4.0 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEQ78233.1 - 1.1e-06 28.6 1.6 1.1e-06 28.6 1.1 3.7 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EEQ78233.1 - 1.7e-06 27.6 5.3 0.02 14.7 1.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger DUF2024 PF09630.5 EEQ78233.1 - 0.024 14.3 3.4 0.093 12.4 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) zf-C2H2 PF00096.21 EEQ78233.1 - 0.093 13.1 0.5 0.093 13.1 0.4 5.1 5 0 0 5 5 5 0 Zinc finger, C2H2 type DUF21 PF01595.15 EEQ78234.1 - 2e-32 111.9 0.1 3.3e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EEQ78234.1 - 9.2e-08 31.7 0.5 0.02 14.6 0.0 3.0 2 0 0 2 2 2 2 CBS domain Bacillus_HBL PF05791.6 EEQ78235.1 - 1.1 8.6 28.4 0.016 14.5 1.4 4.1 4 0 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) IZUMO PF15005.1 EEQ78235.1 - 1.1 9.2 8.5 0.19 11.7 0.6 3.1 3 0 0 3 3 3 0 Izumo sperm-egg fusion AAA_13 PF13166.1 EEQ78235.1 - 1.5 7.1 37.9 0.0033 15.9 8.3 3.4 2 2 1 3 3 3 0 AAA domain MFS_1 PF07690.11 EEQ78237.1 - 9.4e-15 54.1 60.3 2.6e-13 49.4 22.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3290 PF11694.3 EEQ78237.1 - 0.026 14.2 0.2 0.057 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) DUF747 PF05346.6 EEQ78239.1 - 2.3e-128 427.9 5.4 3.2e-128 427.4 3.7 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family Peptidase_M20 PF01546.23 EEQ78240.1 - 5.6e-24 84.6 0.0 1.5e-23 83.3 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EEQ78240.1 - 1e-14 53.7 0.2 4.8e-05 23.0 0.0 5.6 4 1 0 4 4 4 3 WD domain, G-beta repeat M20_dimer PF07687.9 EEQ78240.1 - 6.6e-07 29.0 0.0 1.2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.9 EEQ78240.1 - 0.084 11.6 0.0 0.33 9.6 0.0 1.8 1 1 1 2 2 2 0 M42 glutamyl aminopeptidase PQQ_3 PF13570.1 EEQ78240.1 - 1.5 9.1 5.4 23 5.4 0.0 4.0 4 0 0 4 4 4 0 PQQ-like domain Sulfolobus_pRN PF05584.6 EEQ78241.1 - 0.0056 16.6 0.5 0.0084 16.0 0.3 1.3 1 0 0 1 1 1 1 Sulfolobus plasmid regulatory protein DUF3074 PF11274.3 EEQ78241.1 - 0.047 13.3 1.2 0.05 13.2 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) TraQ PF09679.5 EEQ78242.1 - 0.05 13.5 0.3 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) TRP PF06011.7 EEQ78244.1 - 1.6e-158 527.9 22.9 2.2e-158 527.4 15.9 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EEQ78244.1 - 3.9e-37 127.4 0.1 6.4e-37 126.7 0.1 1.3 1 0 0 1 1 1 1 ML-like domain gpUL132 PF11359.3 EEQ78244.1 - 0.0031 16.8 0.0 0.0066 15.8 0.0 1.5 1 0 0 1 1 1 1 Glycoprotein UL132 Phage_holin_1 PF04531.8 EEQ78244.1 - 0.081 13.0 0.0 0.081 13.0 0.0 4.1 3 1 1 4 4 4 0 Bacteriophage holin DUF1419 PF07215.6 EEQ78244.1 - 0.14 12.0 0.1 0.14 12.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1419) VirB3 PF05101.8 EEQ78244.1 - 1.4 8.9 11.9 6.4 6.8 0.1 4.4 5 0 0 5 5 5 0 Type IV secretory pathway, VirB3-like protein zf-U1 PF06220.7 EEQ78245.1 - 1e-21 76.1 3.0 1.3e-21 75.7 2.1 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EEQ78245.1 - 0.025 14.7 3.3 0.05 13.7 2.3 1.5 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF3602 PF12223.3 EEQ78247.1 - 1e-17 64.2 5.5 1.2e-14 54.4 0.8 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) Actin PF00022.14 EEQ78248.1 - 9.1e-131 435.8 0.0 1e-130 435.7 0.0 1.0 1 0 0 1 1 1 1 Actin Glyco_tran_28_C PF04101.11 EEQ78249.1 - 1.6e-18 66.9 0.1 3.9e-18 65.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EEQ78249.1 - 0.0086 15.2 0.1 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 UDPGT PF00201.13 EEQ78249.1 - 0.15 10.5 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase MRP-S28 PF10213.4 EEQ78250.1 - 3.2e-42 143.5 0.1 5.3e-42 142.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF3006 PF11213.3 EEQ78250.1 - 0.0084 15.8 1.7 0.014 15.1 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) zf-PHD-like PF15446.1 EEQ78252.1 - 4.4e-73 244.2 8.3 1e-72 243.0 5.8 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 EEQ78252.1 - 2.5e-56 190.6 0.1 3.6e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ78252.1 - 5.1e-14 51.8 0.0 1.3e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EEQ78252.1 - 1.2e-10 40.6 2.1 3.3e-10 39.2 1.5 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 EEQ78252.1 - 2.9e-06 26.8 5.1 0.0039 16.8 0.2 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 EEQ78252.1 - 3.5e-06 26.5 4.3 3.5e-06 26.5 3.0 3.8 2 2 1 3 3 3 1 PHD-finger DEAD PF00270.24 EEQ78252.1 - 0.00024 20.6 0.0 0.00048 19.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD_2 PF13831.1 EEQ78252.1 - 0.0059 15.8 3.6 0.0059 15.8 2.5 3.1 3 1 0 3 3 3 1 PHD-finger SnAC PF14619.1 EEQ78252.1 - 0.064 13.4 0.2 0.064 13.4 0.1 3.4 3 0 0 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex Prok-RING_1 PF14446.1 EEQ78252.1 - 2.1 8.1 10.9 0.039 13.7 1.8 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 SpoU_methylase PF00588.14 EEQ78253.1 - 1.7e-26 92.7 0.1 4.5e-26 91.4 0.1 1.7 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EEQ78253.1 - 3.1e-05 24.0 0.0 0.00023 21.2 0.0 2.3 1 1 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding MukB PF04310.7 EEQ78254.1 - 0.12 11.7 0.1 0.15 11.3 0.1 1.1 1 0 0 1 1 1 0 MukB N-terminal Fungal_trans PF04082.13 EEQ78255.1 - 4.5e-05 22.4 0.1 7.3e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.17 EEQ78258.1 - 3.7e-76 256.3 0.0 6.3e-76 255.5 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF750 PF04721.12 EEQ78258.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF750) LuxC PF05893.9 EEQ78258.1 - 0.16 10.6 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) SNF2_N PF00176.18 EEQ78259.1 - 1.6e-82 276.6 0.5 2.6e-82 275.9 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EEQ78259.1 - 4.6e-45 152.1 1.5 4.6e-45 152.1 1.0 2.1 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 EEQ78259.1 - 1e-35 122.4 1.9 1e-35 122.4 1.3 3.8 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 EEQ78259.1 - 4.1e-14 52.1 0.0 2.3e-13 49.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ78259.1 - 1.1e-07 31.8 0.0 7.7e-07 29.1 0.0 2.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EEQ78259.1 - 8.8e-06 25.3 0.0 2.5e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.1 EEQ78259.1 - 0.025 14.4 0.8 0.17 11.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain DEAD_2 PF06733.10 EEQ78259.1 - 0.036 13.4 0.1 0.078 12.3 0.1 1.5 1 0 0 1 1 1 0 DEAD_2 DUF4588 PF15251.1 EEQ78260.1 - 0.0051 16.8 11.4 0.019 14.9 7.9 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) gerPA PF10676.4 EEQ78260.1 - 0.17 11.7 0.8 1.7 8.5 0.1 2.5 2 0 0 2 2 2 0 Spore germination protein gerPA/gerPF DUF605 PF04652.11 EEQ78260.1 - 0.58 9.4 14.6 0.88 8.9 10.1 1.3 1 0 0 1 1 1 0 Vta1 like DUF4225 PF13988.1 EEQ78261.1 - 0.02 14.3 0.2 0.031 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) DUF4536 PF15055.1 EEQ78261.1 - 0.29 11.2 5.3 1.3 9.1 3.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4536) Adap_comp_sub PF00928.16 EEQ78262.1 - 9.3e-51 172.4 0.0 1.7e-50 171.5 0.0 1.4 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EEQ78262.1 - 5.6e-05 22.8 0.0 8.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Bys1 PF04681.7 EEQ78263.1 - 7.5e-101 334.2 0.7 8.6e-101 334.0 0.5 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein ICL PF00463.16 EEQ78265.1 - 1.7e-288 957.1 3.0 1.9e-288 956.9 2.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EEQ78265.1 - 4.5e-11 42.4 1.6 7.1e-11 41.7 0.0 2.0 2 1 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Trehalase PF01204.13 EEQ78267.1 - 4.8e-189 629.2 0.1 5.8e-189 628.9 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EEQ78267.1 - 3.6e-17 61.3 0.5 3.6e-17 61.3 0.3 1.7 2 0 0 2 2 2 1 Neutral trehalase Ca2+ binding domain adh_short PF00106.20 EEQ78268.1 - 8.4e-26 90.8 0.0 1.1e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEQ78268.1 - 2e-25 89.9 0.0 2.5e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEQ78268.1 - 2.6e-08 33.7 0.0 3.8e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 KR domain OTU PF02338.14 EEQ78269.1 - 1.6e-21 77.1 0.1 4.8e-21 75.5 0.0 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EEQ78269.1 - 1.2e-07 31.3 0.0 7.6e-05 22.1 0.0 2.5 2 0 0 2 2 2 2 Peptidase C65 Otubain NfI_DNAbd_pre-N PF10524.4 EEQ78269.1 - 0.0014 18.1 0.5 0.077 12.5 0.0 2.4 2 0 0 2 2 2 1 Nuclear factor I protein pre-N-terminus Cep57_MT_bd PF06657.8 EEQ78269.1 - 0.26 11.2 3.5 0.69 9.9 2.4 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 TPMT PF05724.6 EEQ78270.1 - 8e-33 113.7 0.0 4.1e-28 98.3 0.0 2.1 2 0 0 2 2 2 2 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 EEQ78270.1 - 8.6e-08 32.7 0.0 1.9e-07 31.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ78270.1 - 2.8e-05 23.7 0.0 8.3e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ78270.1 - 3.9e-05 24.0 0.0 6.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ78270.1 - 0.00011 21.9 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ78270.1 - 0.00036 20.5 0.0 0.00053 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ78270.1 - 0.093 13.2 0.0 0.22 12.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 EEQ78271.1 - 2.5e-40 138.3 37.1 2.5e-40 138.3 25.7 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 EEQ78271.1 - 0.0017 16.4 6.7 0.49 8.3 0.2 3.2 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Metallophos PF00149.23 EEQ78275.1 - 7.1e-12 45.1 4.5 6.7e-11 41.9 3.1 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEQ78275.1 - 1.1e-07 31.7 0.1 3.6e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2204 PF09970.4 EEQ78276.1 - 0.0084 15.5 0.0 0.015 14.8 0.0 1.3 1 1 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) HicB PF05534.7 EEQ78276.1 - 0.075 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 HicB family Glyco_hydro_76 PF03663.9 EEQ78278.1 - 6.3e-123 410.8 5.7 8.1e-123 410.4 4.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 MMS19_N PF14500.1 EEQ78278.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II SDA1 PF05285.7 EEQ78278.1 - 0.22 10.7 0.9 0.33 10.2 0.6 1.2 1 0 0 1 1 1 0 SDA1 IL1_propep PF02394.11 EEQ78279.1 - 0.028 14.8 0.0 0.052 13.9 0.0 1.4 1 0 0 1 1 1 0 Interleukin-1 propeptide DDE_Tnp_1_2 PF13586.1 EEQ78279.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain Fungal_trans PF04082.13 EEQ78280.1 - 7e-31 107.0 2.0 1.2e-30 106.3 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ78280.1 - 1.6e-07 31.1 10.2 3.2e-07 30.1 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EEQ78282.1 - 6.7e-70 235.1 0.0 8.5e-70 234.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ78282.1 - 2.7e-30 105.3 0.0 4.1e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ78282.1 - 0.052 13.2 0.1 0.052 13.2 0.1 2.3 2 2 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EEQ78282.1 - 0.081 11.9 0.0 0.22 10.5 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family G_glu_transpept PF01019.16 EEQ78283.1 - 7.1e-145 483.3 0.0 8.2e-145 483.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DnaJ PF00226.26 EEQ78284.1 - 2.1e-07 30.5 0.0 3.2e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EEQ78284.1 - 8e-07 28.9 0.3 1.9e-06 27.6 0.2 1.7 1 1 0 1 1 1 1 Pam16 CRA PF06589.6 EEQ78284.1 - 0.021 14.1 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) DUF3918 PF13056.1 EEQ78284.1 - 0.044 13.0 1.4 0.044 13.0 0.9 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3918) Ribosomal_L24e PF01246.15 EEQ78285.1 - 3.3e-28 97.3 3.3 8.3e-28 96.0 2.3 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.9 EEQ78285.1 - 1.6 8.4 7.1 3.6 7.2 4.6 1.8 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif BUD22 PF09073.5 EEQ78286.1 - 0.12 11.4 4.3 0.17 10.8 3.0 1.1 1 0 0 1 1 1 0 BUD22 zf-C2H2 PF00096.21 EEQ78287.1 - 0.0033 17.6 4.0 0.013 15.8 2.8 2.1 1 0 0 1 1 1 1 Zinc finger, C2H2 type DUF2985 PF11204.3 EEQ78288.1 - 1.3e-37 127.3 3.2 2.4e-37 126.5 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Methyltransf_16 PF10294.4 EEQ78289.1 - 2.5e-08 33.5 0.0 2.8e-06 26.8 0.0 2.2 1 1 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 EEQ78289.1 - 0.083 13.4 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EEQ78290.1 - 1.6e-16 60.8 0.0 4.4e-16 59.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEQ78290.1 - 3.1e-10 39.8 0.0 9.5e-09 35.0 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEQ78290.1 - 2e-06 27.6 0.0 4.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEQ78290.1 - 1.2e-05 25.2 0.0 2.7e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEQ78290.1 - 1.3e-05 25.5 0.0 3.6e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEQ78290.1 - 1.4e-05 25.4 1.0 6e-05 23.4 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEQ78290.1 - 0.00024 21.3 0.0 0.00063 20.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EEQ78290.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CENP-B_dimeris PF09026.5 EEQ78290.1 - 0.014 15.6 4.1 0.027 14.6 2.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NARP1 PF12569.3 EEQ78290.1 - 0.26 9.9 1.4 0.4 9.3 0.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RXT2_N PF08595.6 EEQ78290.1 - 1.1 9.1 3.7 1.7 8.4 2.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP1_TM PF14812.1 EEQ78290.1 - 5.1 7.4 9.8 14 6.0 6.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_S58 PF03576.9 EEQ78291.1 - 1.3e-20 73.8 0.1 1.7e-20 73.5 0.1 1.1 1 0 0 1 1 1 1 Peptidase family S58 DSPc PF00782.15 EEQ78292.1 - 1.2e-22 79.9 0.0 2.7e-20 72.2 0.0 2.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EEQ78292.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Sporozoite_P67 PF05642.6 EEQ78293.1 - 0.051 11.4 0.0 0.059 11.2 0.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Daxx PF03344.10 EEQ78293.1 - 0.25 9.7 7.1 0.31 9.4 5.0 1.1 1 0 0 1 1 1 0 Daxx Family Nucleoplasmin PF03066.10 EEQ78293.1 - 0.39 10.2 4.9 0.57 9.6 3.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 EEQ78293.1 - 0.65 7.9 5.2 0.81 7.6 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Aminotran_3 PF00202.16 EEQ78296.1 - 5.8e-45 153.6 0.0 7.8e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Pterin_4a PF01329.14 EEQ78297.1 - 3.7e-22 77.8 0.7 4.3e-22 77.6 0.5 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Fungal_trans PF04082.13 EEQ78298.1 - 2.4e-16 59.4 0.1 4e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ78298.1 - 5.3e-07 29.4 10.0 1e-06 28.5 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2537 PF10801.3 EEQ78299.1 - 0.0037 17.3 2.1 0.0089 16.1 1.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2537) DUF2695 PF10905.3 EEQ78300.1 - 0.11 12.1 0.1 0.25 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2695) Fungal_trans_2 PF11951.3 EEQ78303.1 - 1.1e-08 34.0 0.5 7.5e-08 31.3 0.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_33 PF10017.4 EEQ78304.1 - 2.1e-20 72.8 0.0 3.1e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent DAO PF01266.19 EEQ78305.1 - 5.3e-40 137.4 0.0 6.2e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEQ78305.1 - 2.3e-05 24.3 0.0 0.0013 18.6 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEQ78305.1 - 0.00011 21.9 0.0 0.53 10.0 0.0 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EEQ78305.1 - 0.00077 19.4 0.0 0.0022 17.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EEQ78305.1 - 0.004 15.8 0.0 0.49 8.9 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.7 EEQ78305.1 - 0.011 14.6 0.0 0.08 11.8 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 EEQ78305.1 - 0.041 14.2 0.0 0.087 13.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EEQ78305.1 - 0.047 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 EEQ78305.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Epimerase PF01370.16 EEQ78307.1 - 4.3e-20 72.1 0.0 6.8e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEQ78307.1 - 1.1e-14 53.7 0.0 1.5e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EEQ78307.1 - 3e-11 42.7 0.1 4.4e-10 38.9 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EEQ78307.1 - 5.2e-11 42.8 0.2 1.4e-10 41.5 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EEQ78307.1 - 2.4e-07 30.8 0.0 5.2e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ78307.1 - 4e-06 26.6 0.0 7.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EEQ78307.1 - 0.00015 20.8 0.0 0.00027 19.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EEQ78307.1 - 0.0035 16.6 0.3 0.011 14.9 0.1 2.0 2 1 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.12 EEQ78307.1 - 0.044 12.6 0.0 0.078 11.8 0.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain KH_1 PF00013.24 EEQ78308.1 - 4.8e-40 135.0 8.9 4.1e-16 58.3 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EEQ78308.1 - 1.7e-29 100.9 11.3 8.7e-12 44.4 1.0 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EEQ78308.1 - 1.2e-10 40.7 6.7 0.0018 17.8 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EEQ78308.1 - 9.1e-09 34.8 2.8 0.063 12.9 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EEQ78308.1 - 0.00053 19.7 4.2 0.4 10.5 0.0 3.4 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 EEQ78308.1 - 0.017 14.6 0.2 2.8 7.4 0.0 3.1 3 0 0 3 3 3 0 dUTPase ADH_N PF08240.7 EEQ78309.1 - 1.8e-28 98.4 0.7 3e-28 97.7 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEQ78309.1 - 7.2e-20 70.8 0.0 1.2e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EEQ78309.1 - 4.5e-05 22.9 0.4 0.00017 21.1 0.3 2.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.16 EEQ78309.1 - 0.085 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 EEQ78309.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Yippee-Mis18 PF03226.9 EEQ78310.1 - 6.4e-24 83.8 1.2 7.2e-24 83.6 0.8 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.1 EEQ78310.1 - 0.0035 17.3 0.6 0.26 11.3 0.0 2.2 1 1 0 2 2 2 1 HNH endonuclease DUF2039 PF10217.4 EEQ78310.1 - 0.0036 17.2 0.9 0.016 15.2 0.1 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) RIG-I_C-RD PF11648.3 EEQ78310.1 - 0.021 14.6 1.8 0.038 13.8 1.3 1.5 1 1 0 1 1 1 0 C-terminal domain of RIG-I Evr1_Alr PF04777.8 EEQ78310.1 - 0.022 14.6 1.3 0.59 10.0 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family DUF4451 PF14616.1 EEQ78310.1 - 0.025 14.3 0.4 0.033 13.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) Endonuclease_7 PF02945.10 EEQ78310.1 - 0.038 13.7 1.1 0.099 12.3 0.7 1.8 1 1 0 1 1 1 0 Recombination endonuclease VII SH2_2 PF14633.1 EEQ78310.1 - 0.045 12.8 0.0 0.06 12.4 0.0 1.1 1 0 0 1 1 1 0 SH2 domain GFA PF04828.9 EEQ78310.1 - 0.054 13.4 2.0 0.27 11.2 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Elf1 PF05129.8 EEQ78310.1 - 0.16 11.6 1.2 1.2 8.8 0.1 2.1 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like RabGAP-TBC PF00566.13 EEQ78312.1 - 3.6e-35 121.3 0.3 5.5e-35 120.7 0.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 EEQ78313.1 - 2.7e-60 203.7 0.0 3.9e-60 203.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ78313.1 - 4.4e-22 78.3 0.0 7.2e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ78313.1 - 9.6e-07 28.0 0.0 1.6e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEQ78313.1 - 9.4e-05 22.2 0.2 0.0062 16.2 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EEQ78313.1 - 0.00035 19.9 0.2 0.00095 18.5 0.1 1.7 2 0 0 2 2 2 1 RIO1 family PAS_9 PF13426.1 EEQ78313.1 - 0.13 12.6 0.0 2.5 8.4 0.0 3.1 3 1 0 3 3 3 0 PAS domain Seadorna_VP7 PF07387.6 EEQ78313.1 - 0.15 10.8 0.1 0.3 9.8 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 F-box-like PF12937.2 EEQ78315.1 - 1.9e-13 49.9 0.0 7.1e-13 48.0 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ78315.1 - 1.4e-11 43.7 0.1 6.6e-11 41.5 0.0 2.4 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.1 EEQ78315.1 - 1.4e-09 37.0 26.3 0.041 13.9 0.0 9.8 11 0 0 11 11 11 4 Leucine Rich repeat LRR_4 PF12799.2 EEQ78315.1 - 0.00059 19.4 23.6 0.23 11.1 1.2 6.5 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EEQ78315.1 - 0.0017 18.1 26.9 0.2 11.8 0.3 8.0 8 1 0 8 8 8 3 Leucine Rich Repeat PRANC PF09372.5 EEQ78315.1 - 0.0026 17.6 0.0 0.0099 15.8 0.0 2.0 1 0 0 1 1 1 1 PRANC domain LRR_7 PF13504.1 EEQ78315.1 - 1.7 9.1 28.8 1.4 9.4 0.1 8.8 10 0 0 10 10 10 0 Leucine rich repeat DUF2361 PF10153.4 EEQ78316.1 - 6.8e-36 122.9 7.6 6.8e-36 122.9 5.3 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) zf-rbx1 PF12678.2 EEQ78317.1 - 0.0022 18.0 3.8 0.0059 16.6 2.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger WD40 PF00400.27 EEQ78317.1 - 0.012 15.5 1.7 1.3 9.0 0.1 4.5 4 1 0 4 4 4 0 WD domain, G-beta repeat zf-RING_2 PF13639.1 EEQ78317.1 - 5.4 6.9 13.4 0.069 12.9 3.3 2.3 2 1 0 2 2 2 0 Ring finger domain Stb3 PF10330.4 EEQ78318.1 - 2e-37 126.7 0.0 3.3e-37 126.0 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein Mito_carr PF00153.22 EEQ78320.1 - 2.4e-67 222.6 5.1 1.6e-24 85.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Kri1_C PF12936.2 EEQ78321.1 - 2.9e-30 104.0 0.0 2.9e-30 104.0 0.0 4.2 2 2 2 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.7 EEQ78321.1 - 4.9e-30 103.7 18.0 4.9e-30 103.7 12.5 5.6 3 1 0 4 4 4 1 KRI1-like family AHS2 PF02626.10 EEQ78321.1 - 0.099 11.9 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Allophanate hydrolase subunit 2 PH PF00169.24 EEQ78322.1 - 1.1e-07 31.9 0.0 4.4e-07 30.0 0.0 2.1 1 0 0 1 1 1 1 PH domain GRAM PF02893.15 EEQ78322.1 - 0.00012 21.5 0.1 0.0004 19.8 0.0 1.9 2 0 0 2 2 2 1 GRAM domain PH_11 PF15413.1 EEQ78322.1 - 0.65 10.2 7.5 14 5.9 0.3 3.3 2 1 0 2 2 2 0 Pleckstrin homology domain Sen15 PF09631.5 EEQ78323.1 - 3.8e-18 65.5 0.0 3.8e-11 43.1 0.0 2.2 2 0 0 2 2 2 2 Sen15 protein Glypican PF01153.14 EEQ78323.1 - 0.052 12.1 0.4 0.064 11.8 0.3 1.1 1 0 0 1 1 1 0 Glypican Serglycin PF04360.7 EEQ78323.1 - 0.078 12.7 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Serglycin UAA PF08449.6 EEQ78324.1 - 1.2e-65 221.4 7.8 5.6e-65 219.2 5.4 1.8 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EEQ78324.1 - 7.8e-07 28.4 0.7 0.0014 17.8 0.2 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 EEQ78324.1 - 3.4e-05 23.9 18.7 0.0008 19.5 4.1 2.5 2 1 0 2 2 2 2 Multidrug resistance efflux transporter EamA PF00892.15 EEQ78324.1 - 3.8e-05 23.7 25.5 0.0014 18.6 5.2 2.6 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 EEQ78324.1 - 0.0078 15.8 8.0 0.0078 15.8 5.5 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family Rotamase_3 PF13616.1 EEQ78326.1 - 1.2e-16 61.0 0.1 2.2e-16 60.1 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 EEQ78326.1 - 4.5e-15 56.1 0.1 7.8e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EEQ78326.1 - 0.0043 17.6 0.0 0.0063 17.1 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain 2OG-FeII_Oxy_2 PF13532.1 EEQ78327.1 - 2e-14 53.8 0.0 2.6e-13 50.2 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EEQ78327.1 - 0.00016 21.9 0.0 0.00031 20.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Steroid_dh PF02544.11 EEQ78328.1 - 1.1e-11 44.7 0.7 6.5e-11 42.2 0.3 2.2 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase GVQW PF13900.1 EEQ78328.1 - 0.12 12.4 1.4 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 Putative binding domain Ank_2 PF12796.2 EEQ78329.1 - 7.1e-27 93.5 0.1 7.3e-19 67.9 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEQ78329.1 - 1.5e-24 85.4 0.3 4.3e-10 39.5 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EEQ78329.1 - 1.9e-21 74.7 0.2 5.5e-07 29.0 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EEQ78329.1 - 1.9e-16 60.0 0.1 1.3e-09 38.3 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEQ78329.1 - 2.3e-15 55.1 0.0 3.7e-05 23.5 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ribosomal_L7Ae PF01248.21 EEQ78330.1 - 1.7e-26 91.5 0.5 2.1e-26 91.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 EEQ78330.1 - 0.053 13.1 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Vac_ImportDeg PF09783.4 EEQ78331.1 - 1.6e-38 131.9 3.6 4.3e-37 127.3 1.5 2.9 2 1 0 2 2 2 1 Vacuolar import and degradation protein MR_MLE_C PF13378.1 EEQ78332.1 - 5.4e-33 113.2 0.0 1.1e-32 112.2 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 EEQ78332.1 - 9.5e-19 67.5 0.0 1.9e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 EEQ78332.1 - 7.3e-08 32.8 0.0 2.1e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain IU_nuc_hydro PF01156.14 EEQ78333.1 - 3.8e-85 285.8 0.0 4.4e-85 285.6 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase PXA PF02194.10 EEQ78334.1 - 8.9e-43 146.0 0.2 1.3e-42 145.4 0.2 1.2 1 0 0 1 1 1 1 PXA domain HTH_Tnp_Tc5 PF03221.11 EEQ78336.1 - 2.9e-15 55.8 0.3 5.1e-15 55.0 0.2 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain TGS PF02824.16 EEQ78340.1 - 2.3e-23 81.7 0.0 8.8e-23 79.9 0.0 2.0 2 0 0 2 2 2 1 TGS domain MMR_HSR1 PF01926.18 EEQ78340.1 - 1.6e-18 66.7 0.2 3.6e-18 65.6 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEQ78340.1 - 1.3e-09 37.5 0.2 6.7e-09 35.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EEQ78340.1 - 0.00014 21.6 0.1 0.016 15.0 0.0 2.4 2 0 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 EEQ78340.1 - 0.00032 20.1 0.3 2.6 7.4 0.0 4.0 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain Miro PF08477.8 EEQ78340.1 - 0.0059 17.0 0.0 0.018 15.5 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 EEQ78340.1 - 0.012 14.4 0.1 0.026 13.2 0.1 1.5 1 0 0 1 1 1 0 ArgK protein CDO_I PF05995.7 EEQ78341.1 - 9.8e-42 142.0 0.0 1.2e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EEQ78341.1 - 1.6e-05 24.4 0.0 1.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) Glyco_transf_90 PF05686.7 EEQ78342.1 - 3.5e-15 55.6 15.1 5.4e-12 45.1 8.0 3.4 2 1 0 2 2 2 2 Glycosyl transferase family 90 IncA PF04156.9 EEQ78342.1 - 0.0015 18.2 1.2 0.0025 17.4 0.8 1.3 1 0 0 1 1 1 1 IncA protein SpoIIIAH PF12685.2 EEQ78342.1 - 0.0033 16.9 0.3 0.0056 16.1 0.2 1.3 1 0 0 1 1 1 1 SpoIIIAH-like protein PP_M1 PF03012.9 EEQ78342.1 - 0.13 11.6 3.8 0.2 10.9 2.6 1.2 1 0 0 1 1 1 0 Phosphoprotein Suf PF05843.9 EEQ78342.1 - 1.4 8.6 10.8 2.2 7.9 7.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4175 PF13779.1 EEQ78342.1 - 4 5.0 17.2 5.7 4.5 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PAT1 PF09770.4 EEQ78342.1 - 8.2 4.5 20.3 12 4.0 14.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Abhydrolase_6 PF12697.2 EEQ78343.1 - 9.9e-21 74.6 2.4 4.9e-20 72.4 1.6 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ78343.1 - 3.7e-08 33.2 0.0 4.3e-05 23.1 0.0 3.0 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ78343.1 - 1.5e-06 28.0 0.0 6.5e-06 25.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Glyco_transf_8 PF01501.15 EEQ78344.1 - 3.7e-34 118.1 0.0 6e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Ferric_reduct PF01794.14 EEQ78345.1 - 3.8e-08 33.4 5.2 3.8e-08 33.4 3.6 2.7 2 2 1 3 3 3 1 Ferric reductase like transmembrane component NMN_transporter PF04973.7 EEQ78345.1 - 0.023 14.1 0.7 0.023 14.1 0.5 1.7 2 0 0 2 2 2 0 Nicotinamide mononucleotide transporter ResB PF05140.9 EEQ78345.1 - 0.031 12.8 0.5 0.042 12.3 0.4 1.1 1 0 0 1 1 1 0 ResB-like family HEAT PF02985.17 EEQ78346.1 - 2.2e-42 139.3 16.3 0.0028 17.5 0.1 12.4 13 0 0 13 13 13 11 HEAT repeat HEAT_2 PF13646.1 EEQ78346.1 - 1.2e-33 115.2 1.4 7.5e-09 35.7 0.0 7.2 3 2 3 6 6 6 6 HEAT repeats Vac14_Fab1_bd PF12755.2 EEQ78346.1 - 8.1e-12 45.3 3.7 0.0011 19.2 0.1 7.0 4 2 4 8 8 8 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EEQ78346.1 - 5.9e-11 42.5 5.8 0.018 15.5 0.0 8.1 6 2 3 9 9 9 2 HEAT-like repeat Adaptin_N PF01602.15 EEQ78346.1 - 7.9e-06 24.4 3.6 0.25 9.5 0.1 3.9 1 1 3 4 4 4 3 Adaptin N terminal region Arm PF00514.18 EEQ78346.1 - 0.0025 17.5 5.3 2.4 8.1 0.0 5.6 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 EEQ78346.1 - 0.0048 16.7 2.9 3.9 7.4 0.1 4.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) CLASP_N PF12348.3 EEQ78346.1 - 0.012 14.9 1.9 1.9 7.7 0.1 4.2 3 2 1 4 4 4 0 CLASP N terminal Cnd3 PF12719.2 EEQ78346.1 - 0.039 12.9 0.4 0.13 11.1 0.2 1.8 1 1 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain MR_MLE PF01188.16 EEQ78346.1 - 0.046 14.2 0.0 0.22 12.0 0.0 2.2 2 0 0 2 2 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Proteasom_PSMB PF10508.4 EEQ78346.1 - 0.35 9.0 4.9 0.74 8.0 0.0 2.9 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit Cnd1 PF12717.2 EEQ78346.1 - 0.58 9.9 4.8 10 5.8 0.1 4.3 3 1 2 5 5 5 0 non-SMC mitotic condensation complex subunit 1 B3_4 PF03483.12 EEQ78347.1 - 5.2e-24 84.6 0.0 9.9e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EEQ78347.1 - 1.1e-18 66.7 0.0 3.6e-15 55.5 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain Ribosomal_S3_C PF00189.15 EEQ78348.1 - 5e-17 61.8 0.1 1e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EEQ78348.1 - 2.9e-12 45.9 0.1 4.9e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EEQ78348.1 - 0.061 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Myotub-related PF06602.9 EEQ78349.1 - 3.5e-123 410.8 0.0 4.6e-123 410.4 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EEQ78349.1 - 0.031 14.5 0.2 0.087 13.0 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 EEQ78349.1 - 0.075 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF4129 PF13559.1 EEQ78350.1 - 0.047 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) Dicty_CAR PF05462.6 EEQ78351.1 - 3.7e-05 22.7 1.9 3.7e-05 22.7 1.3 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 EEQ78351.1 - 0.00018 20.6 3.9 0.00037 19.6 2.7 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GATA PF00320.22 EEQ78351.1 - 0.085 12.2 0.0 0.22 10.8 0.0 1.7 1 0 0 1 1 1 0 GATA zinc finger SLS PF14611.1 EEQ78352.1 - 3.4e-59 199.8 0.0 1.3e-58 197.9 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator NT-C2 PF10358.4 EEQ78353.1 - 4.7e-32 110.4 0.0 6.1e-32 110.0 0.0 1.1 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Vir_act_alpha_C PF10400.4 EEQ78354.1 - 0.11 12.8 4.9 0.1 12.9 2.4 1.6 1 1 1 2 2 2 0 Virulence activator alpha C-term Cas_Csy4 PF09618.5 EEQ78354.1 - 1.2 8.9 4.2 1.5 8.5 2.9 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) TMPIT PF07851.8 EEQ78354.1 - 4.7 6.2 6.0 5.4 5.9 4.2 1.0 1 0 0 1 1 1 0 TMPIT-like protein IncA PF04156.9 EEQ78354.1 - 9.6 5.7 7.2 13 5.3 5.0 1.2 1 0 0 1 1 1 0 IncA protein SF3b10 PF07189.6 EEQ78359.1 - 6.3e-36 122.0 0.0 7e-36 121.8 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) A_deamin PF02137.13 EEQ78360.1 - 5.4e-43 147.6 0.0 2.2e-42 145.6 0.0 2.0 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain ERG4_ERG24 PF01222.12 EEQ78361.1 - 8.6e-150 499.0 2.6 9.8e-150 498.8 1.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EEQ78361.1 - 0.001 18.4 0.3 0.0022 17.3 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Man-6-P_recep PF02157.10 EEQ78362.1 - 6.2e-09 35.2 0.1 9.7e-09 34.6 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 EEQ78362.1 - 5e-06 26.3 0.0 0.0068 16.1 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 EEQ78362.1 - 0.013 14.6 0.0 0.013 14.6 0.0 2.6 1 1 1 2 2 2 0 Autophagy-related protein 27 Fungal_trans PF04082.13 EEQ78363.1 - 8.1e-24 83.8 0.0 1.4e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ78363.1 - 5.4e-09 35.8 10.9 9.1e-09 35.0 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IL4 PF00727.13 EEQ78364.1 - 0.097 12.5 0.2 0.62 9.9 0.0 2.5 2 1 0 2 2 2 0 Interleukin 4 Glyco_hydro_3 PF00933.16 EEQ78365.1 - 5.5e-92 307.9 0.0 7.7e-92 307.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EEQ78365.1 - 3.7e-57 193.4 0.3 1.4e-56 191.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EEQ78365.1 - 4.8e-12 45.6 0.1 1e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Lig_chan PF00060.21 EEQ78366.1 - 0.13 11.9 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Ligand-gated ion channel EBP PF05241.7 EEQ78367.1 - 6.9e-05 21.9 0.2 6.9e-05 21.9 0.1 2.1 2 1 0 2 2 2 1 Emopamil binding protein BBS2_N PF14781.1 EEQ78367.1 - 0.1 12.2 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal Zn_clus PF00172.13 EEQ78368.1 - 0.0058 16.5 10.5 0.011 15.6 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EEQ78368.1 - 0.97 9.6 10.0 0.93 9.7 5.9 1.7 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Scs3p PF10261.4 EEQ78370.1 - 2e-60 203.8 7.5 2.4e-60 203.5 5.2 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM DUF3353 PF11833.3 EEQ78370.1 - 0.07 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) Erythro_esteras PF05139.9 EEQ78372.1 - 3.1e-146 487.0 1.7 3.6e-146 486.7 1.2 1.0 1 0 0 1 1 1 1 Erythromycin esterase DUF3535 PF12054.3 EEQ78374.1 - 1.9e-152 507.9 0.1 5e-152 506.5 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EEQ78374.1 - 3.8e-72 242.6 0.0 5.6e-72 242.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEQ78374.1 - 5.6e-15 54.9 0.1 4.1e-14 52.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEAT PF02985.17 EEQ78374.1 - 4.6e-12 44.9 14.3 1.1 9.5 0.0 9.5 9 0 0 9 9 9 5 HEAT repeat Vac14_Fab1_bd PF12755.2 EEQ78374.1 - 1.2e-05 25.5 0.4 0.55 10.6 0.0 3.6 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EEQ78374.1 - 0.00046 19.6 0.2 0.068 12.5 0.0 3.6 2 1 2 4 4 4 1 CLASP N terminal Ndufs5 PF10200.4 EEQ78375.1 - 0.0018 18.1 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 EEQ78375.1 - 0.013 15.6 0.4 0.021 14.9 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Sec39 PF08314.6 EEQ78376.1 - 1.7e-239 796.5 0.0 1.9e-239 796.3 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 EHN PF06441.7 EEQ78377.1 - 2e-23 82.4 0.1 4.6e-23 81.2 0.1 1.6 1 1 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.15 EEQ78377.1 - 7.3e-07 28.9 0.2 3.6e-06 26.7 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEQ78377.1 - 0.00028 20.8 0.2 0.002 18.0 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family CBM_20 PF00686.14 EEQ78377.1 - 0.058 13.0 0.0 0.59 9.7 0.0 2.1 1 1 1 2 2 2 0 Starch binding domain Pkinase PF00069.20 EEQ78378.1 - 8.3e-61 205.3 0.0 1e-60 205.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ78378.1 - 4.5e-36 124.2 0.0 6.3e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ78378.1 - 6.5e-09 35.1 0.0 9.8e-09 34.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Protoglobin PF11563.3 EEQ78381.1 - 4.1e-48 163.0 0.0 4.7e-48 162.8 0.0 1.0 1 0 0 1 1 1 1 Protoglobin TPPK_C PF12555.3 EEQ78383.1 - 0.052 13.2 1.9 0.085 12.5 0.6 1.9 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Dynamin_N PF00350.18 EEQ78387.1 - 8.2e-13 48.5 6.3 6.4e-12 45.6 0.0 3.8 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EEQ78387.1 - 6.6e-06 26.0 0.3 0.00017 21.4 0.2 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EEQ78387.1 - 0.00053 20.2 0.3 0.0016 18.7 0.0 2.0 2 0 0 2 2 1 1 ABC transporter DUF258 PF03193.11 EEQ78387.1 - 0.0006 19.0 0.1 0.0024 17.0 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 T2SE PF00437.15 EEQ78387.1 - 0.001 18.0 0.0 0.0019 17.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Arch_ATPase PF01637.13 EEQ78387.1 - 0.0026 17.4 0.1 0.25 11.0 0.0 2.8 2 0 0 2 2 2 1 Archaeal ATPase IIGP PF05049.8 EEQ78387.1 - 0.0053 15.6 0.0 0.014 14.2 0.0 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Miro PF08477.8 EEQ78387.1 - 0.009 16.5 0.0 0.023 15.1 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_17 PF13207.1 EEQ78387.1 - 0.015 16.1 1.5 0.085 13.6 0.0 3.0 3 1 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 EEQ78387.1 - 0.018 14.1 0.8 0.04 12.9 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin Adeno_IVa2 PF02456.10 EEQ78387.1 - 0.021 13.4 0.0 0.04 12.5 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein AIG1 PF04548.11 EEQ78387.1 - 0.021 13.9 2.0 0.091 11.8 0.0 2.6 2 0 0 2 2 2 0 AIG1 family DUF87 PF01935.12 EEQ78387.1 - 0.044 13.5 0.2 0.43 10.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_29 PF13555.1 EEQ78387.1 - 0.067 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ArgK PF03308.11 EEQ78387.1 - 0.11 11.2 0.0 0.23 10.2 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_23 PF13476.1 EEQ78387.1 - 0.7 10.1 0.0 0.7 10.1 0.0 3.7 4 0 0 4 4 4 0 AAA domain DUF4451 PF14616.1 EEQ78389.1 - 1.3e-34 118.6 0.6 2.8e-34 117.5 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) TPR_11 PF13414.1 EEQ78390.1 - 7e-46 153.7 32.7 1.7e-18 65.9 1.7 6.3 4 2 2 6 6 6 5 TPR repeat TPR_2 PF07719.12 EEQ78390.1 - 1e-36 121.8 21.3 2.6e-06 26.9 0.2 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.23 EEQ78390.1 - 2.1e-36 122.0 19.9 8.8e-09 34.6 0.4 8.6 9 0 0 9 9 8 6 Tetratricopeptide repeat DnaJ PF00226.26 EEQ78390.1 - 8.8e-28 95.8 1.9 8.8e-28 95.8 1.3 3.9 5 0 0 5 5 3 1 DnaJ domain TPR_16 PF13432.1 EEQ78390.1 - 5.6e-25 87.4 16.1 8.4e-08 32.6 0.2 6.0 3 3 2 5 5 5 5 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ78390.1 - 1.2e-24 86.4 16.0 2e-05 24.8 0.6 6.4 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ78390.1 - 9.6e-24 81.7 13.6 0.0002 21.7 0.2 8.3 3 3 5 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ78390.1 - 4.8e-20 69.7 5.6 0.016 15.0 0.0 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ78390.1 - 7.1e-18 64.3 18.3 0.00015 21.6 0.7 6.1 3 2 1 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ78390.1 - 1.9e-16 58.7 16.2 0.00056 19.8 0.3 8.0 8 0 0 8 8 8 4 Tetratricopeptide repeat Apc3 PF12895.2 EEQ78390.1 - 4.4e-16 58.7 8.6 1.6e-07 31.3 1.2 3.8 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EEQ78390.1 - 1.7e-15 55.5 21.8 0.00074 19.1 0.4 8.4 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 EEQ78390.1 - 3.8e-13 48.9 15.6 0.0012 19.1 0.0 7.8 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ78390.1 - 6.1e-10 38.8 8.4 0.009 15.8 0.1 5.6 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_15 PF13429.1 EEQ78390.1 - 1.1e-07 31.2 7.1 0.024 13.6 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat ChAPs PF09295.5 EEQ78390.1 - 3.7e-05 22.6 0.7 0.19 10.4 0.0 2.9 2 1 1 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) MIT PF04212.13 EEQ78390.1 - 0.0001 22.0 6.0 0.27 11.1 0.3 4.7 2 1 2 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_4 PF07721.9 EEQ78390.1 - 0.00012 22.1 1.9 2.5 8.7 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat BTAD PF03704.12 EEQ78390.1 - 0.00035 20.8 6.6 0.45 10.7 0.0 3.9 2 2 1 4 4 4 2 Bacterial transcriptional activator domain Alkyl_sulf_dimr PF14863.1 EEQ78390.1 - 0.0011 19.1 8.3 0.48 10.6 0.1 4.2 3 2 2 5 5 4 1 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.1 EEQ78390.1 - 0.0014 18.4 9.2 3.3 7.6 0.1 4.8 3 1 2 5 5 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 EEQ78390.1 - 0.0027 17.7 11.2 2.8 8.1 0.1 5.0 2 2 3 5 5 5 1 Tetratricopeptide repeat PPR PF01535.15 EEQ78390.1 - 0.037 13.9 0.0 56 4.0 0.0 4.6 4 0 0 4 4 4 0 PPR repeat SHNi-TPR PF10516.4 EEQ78390.1 - 0.056 12.6 4.5 16 4.8 0.1 4.4 4 0 0 4 4 4 0 SHNi-TPR TPR_3 PF07720.7 EEQ78390.1 - 0.17 11.7 5.1 3.2 7.6 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EEQ78390.1 - 0.96 9.4 15.9 4 7.5 0.0 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF3856 PF12968.2 EEQ78390.1 - 4.1 7.2 9.4 96 2.7 0.2 5.4 4 2 0 4 4 4 0 Domain of Unknown Function (DUF3856) DUF4098 PF13345.1 EEQ78392.1 - 3.5e-06 26.8 1.1 0.023 14.6 0.0 3.6 3 0 0 3 3 3 3 Domain of unknown function (DUF4098) HC2 PF07382.6 EEQ78393.1 - 0.00029 20.7 35.8 0.00046 20.1 24.8 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 MFS_1 PF07690.11 EEQ78394.1 - 9e-35 120.0 46.4 2.2e-30 105.5 12.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Spore_III_AE PF09546.5 EEQ78394.1 - 0.00098 18.1 5.3 0.002 17.1 3.6 1.4 1 0 0 1 1 1 1 Stage III sporulation protein AE (spore_III_AE) YoqO PF14037.1 EEQ78394.1 - 0.029 14.4 1.9 0.032 14.3 0.1 2.0 2 0 0 2 2 2 0 YoqO-like protein HemY_N PF07219.8 EEQ78394.1 - 7.5 6.1 6.1 2 8.0 0.4 2.8 3 0 0 3 3 3 0 HemY protein N-terminus Epiglycanin_C PF14654.1 EEQ78394.1 - 8 6.5 8.9 3.5 7.6 0.1 3.9 4 0 0 4 4 4 0 Mucin, catalytic, TM and cytoplasmic tail region Pkinase PF00069.20 EEQ78395.1 - 1.8e-37 128.9 0.0 2.7e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ78395.1 - 1.7e-28 99.4 0.0 2.4e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ78395.1 - 0.0011 18.0 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEQ78395.1 - 0.12 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Med10 PF09748.4 EEQ78396.1 - 3.3e-43 146.5 0.0 3.9e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Peptidase_M28 PF04389.12 EEQ78398.1 - 6.5e-33 113.9 0.5 1.6e-32 112.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 EEQ78398.1 - 0.015 14.7 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 TPR_11 PF13414.1 EEQ78399.1 - 5.3e-07 29.1 0.0 0.0013 18.3 0.0 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EEQ78399.1 - 6.1e-05 22.4 1.1 0.075 12.6 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ78399.1 - 0.00022 20.9 0.1 0.41 10.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ78399.1 - 0.013 15.2 0.3 0.046 13.5 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ78399.1 - 0.024 14.3 0.0 1.9 8.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ78399.1 - 0.03 14.2 0.1 0.78 9.7 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ78399.1 - 0.03 15.0 0.4 0.07 13.8 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ78399.1 - 0.065 13.4 0.1 5.3 7.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat F-box-like PF12937.2 EEQ78400.1 - 7.2e-12 44.8 3.1 1e-11 44.3 0.8 2.4 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 EEQ78400.1 - 1.3e-08 34.4 20.8 0.11 12.2 0.1 6.6 4 2 3 7 7 7 6 Leucine rich repeat LRR_4 PF12799.2 EEQ78400.1 - 3.2e-08 33.0 14.1 0.73 9.5 0.1 7.8 5 2 5 10 10 10 4 Leucine Rich repeats (2 copies) F-box PF00646.28 EEQ78400.1 - 3.4e-07 29.7 5.9 4.8e-06 26.0 1.5 2.8 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.1 EEQ78400.1 - 1.1e-06 28.1 18.6 5 7.5 0.1 11.2 14 1 0 14 14 14 1 Leucine Rich repeat LRR_1 PF00560.28 EEQ78400.1 - 0.015 15.2 28.3 33 5.0 0.1 10.5 9 3 0 9 9 9 0 Leucine Rich Repeat Adeno_E4_34 PF04528.8 EEQ78400.1 - 0.016 14.7 7.7 1.9 8.0 2.3 2.9 2 0 0 2 2 2 0 Adenovirus early E4 34 kDa protein conserved region DUF1699 PF08004.6 EEQ78400.1 - 0.017 14.6 2.3 0.35 10.3 0.1 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1699) STAS_2 PF13466.1 EEQ78400.1 - 0.032 14.2 0.3 0.2 11.7 0.1 2.6 2 0 0 2 2 2 0 STAS domain PyrBI_leader PF08052.6 EEQ78401.1 - 0.023 14.5 1.0 0.054 13.3 0.7 1.7 1 0 0 1 1 1 0 PyrBI operon leader peptide AMP-binding PF00501.23 EEQ78402.1 - 7.1e-64 215.7 0.0 1.2e-63 214.9 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEQ78402.1 - 7.8e-16 58.7 0.1 1.6e-15 57.7 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ribosomal_L13 PF00572.13 EEQ78403.1 - 1.6e-27 96.0 0.0 3.1e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L13 Metallophos PF00149.23 EEQ78404.1 - 8.4e-14 51.4 0.2 1.1e-13 51.0 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEQ78404.1 - 4.1e-07 29.9 0.0 7.3e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EEQ78404.1 - 0.083 12.0 0.0 0.27 10.3 0.0 1.7 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily Glyco_transf_41 PF13844.1 EEQ78407.1 - 4.9e-102 341.3 0.0 2.1e-53 180.9 0.0 3.1 2 1 1 3 3 3 2 Glycosyl transferase family 41 TPR_11 PF13414.1 EEQ78407.1 - 1e-21 76.3 16.7 1.1e-08 34.5 0.1 4.8 4 0 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 EEQ78407.1 - 3.2e-16 58.1 12.4 0.003 17.1 0.1 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ78407.1 - 6e-16 57.0 14.1 0.0011 18.6 0.0 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ78407.1 - 4.3e-14 52.2 6.4 9.3e-06 25.4 0.2 4.4 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ78407.1 - 1.3e-11 44.8 13.6 3.1e-05 24.4 0.5 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ78407.1 - 1.2e-10 41.0 9.4 0.0031 17.9 0.1 5.7 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ78407.1 - 3e-10 39.4 5.5 0.21 11.8 0.2 5.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 EEQ78407.1 - 1.8e-09 37.1 10.7 0.026 14.4 0.3 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ78407.1 - 3.4e-09 35.8 7.4 0.22 11.4 0.0 6.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ78407.1 - 1e-08 34.3 4.3 0.0069 16.0 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ78407.1 - 1.6e-08 34.7 3.7 0.0035 17.6 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_5 PF12688.2 EEQ78407.1 - 0.00079 19.4 1.2 0.16 11.9 0.1 3.0 3 0 0 3 3 3 1 Tetratrico peptide repeat BTAD PF03704.12 EEQ78407.1 - 0.002 18.4 0.7 3.6 7.8 0.1 3.2 3 0 0 3 3 2 2 Bacterial transcriptional activator domain TPR_6 PF13174.1 EEQ78407.1 - 0.0029 17.9 3.5 7 7.3 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EEQ78407.1 - 0.0036 17.4 2.5 0.14 12.2 0.0 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EEQ78407.1 - 0.015 15.1 5.2 1.9 8.4 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.9 EEQ78407.1 - 0.14 11.3 0.0 0.77 8.8 0.0 2.0 2 0 0 2 2 2 0 Coatomer epsilon subunit TPR_4 PF07721.9 EEQ78407.1 - 0.16 12.4 2.5 9.8 6.9 0.4 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.26 EEQ78411.1 - 1e-23 83.1 1.9 9e-13 48.0 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEQ78411.1 - 4.9e-18 64.9 2.7 2e-12 46.9 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF2774 PF11242.3 EEQ78411.1 - 0.0019 18.1 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2774) HTH_38 PF13936.1 EEQ78411.1 - 0.024 14.1 0.1 0.052 13.1 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Myb_DNA-bind_4 PF13837.1 EEQ78411.1 - 0.036 14.1 0.8 0.14 12.3 0.1 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain HTH_23 PF13384.1 EEQ78411.1 - 0.071 12.7 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EEQ78411.1 - 0.17 11.3 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 SBF PF01758.11 EEQ78413.1 - 6.7e-41 139.7 11.3 6.7e-41 139.7 7.9 2.4 2 2 1 3 3 3 2 Sodium Bile acid symporter family PsbI PF02532.9 EEQ78413.1 - 0.52 9.9 3.9 2.3 7.9 2.7 2.1 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) DUF2414 PF10309.4 EEQ78414.1 - 8.9e-22 76.5 0.0 1.4e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) WD40 PF00400.27 EEQ78415.1 - 0.0011 18.7 2.0 5.1 7.1 0.0 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat LisH PF08513.6 EEQ78415.1 - 0.0017 18.0 0.1 0.0036 17.0 0.0 1.6 1 0 0 1 1 1 1 LisH PQQ PF01011.16 EEQ78415.1 - 0.018 14.5 0.1 0.063 12.8 0.1 1.9 1 0 0 1 1 1 0 PQQ enzyme repeat Ribosomal_L29e PF01779.12 EEQ78416.1 - 2.2e-19 69.0 8.8 3.4e-19 68.4 6.1 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family Ribosomal_S5_C PF03719.10 EEQ78416.1 - 0.14 11.4 0.2 3.1 7.1 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain ATP-synt_DE_N PF02823.11 EEQ78417.1 - 1.1e-19 69.8 0.2 1.5e-19 69.4 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF3180 PF11377.3 EEQ78418.1 - 0.0034 17.2 0.5 0.012 15.4 0.1 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3180) PQ-loop PF04193.9 EEQ78419.1 - 3.3e-39 132.2 11.6 2.6e-19 68.5 2.8 2.7 2 0 0 2 2 2 2 PQ loop repeat GRA6 PF05084.8 EEQ78419.1 - 0.078 12.5 0.2 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Granule antigen protein (GRA6) zf-C2H2_4 PF13894.1 EEQ78420.1 - 3.4e-07 30.1 3.0 0.00035 20.6 1.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ78420.1 - 2.5e-05 24.3 3.3 0.002 18.3 1.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEQ78420.1 - 0.043 14.1 4.3 0.98 9.8 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-Di19 PF05605.7 EEQ78420.1 - 0.08 13.0 1.0 0.17 12.0 0.7 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding APH PF01636.18 EEQ78422.1 - 1e-39 136.6 0.0 2.5e-39 135.4 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EEQ78422.1 - 8.1e-06 25.1 0.1 1.4e-05 24.3 0.1 1.5 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 EEQ78422.1 - 1e-05 25.2 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EEQ78422.1 - 9.5e-05 21.5 0.0 0.00043 19.4 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Fructosamin_kin PF03881.9 EEQ78422.1 - 0.0098 14.8 0.0 0.31 9.9 0.0 2.3 1 1 0 1 1 1 1 Fructosamine kinase DUF1679 PF07914.6 EEQ78422.1 - 0.059 12.0 0.0 0.12 10.9 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) RIO1 PF01163.17 EEQ78422.1 - 0.082 12.2 0.0 0.6 9.4 0.0 2.1 2 0 0 2 2 2 0 RIO1 family dUTPase PF00692.14 EEQ78423.1 - 7.3e-13 48.0 0.0 7.4e-07 28.6 0.0 3.0 1 1 1 2 2 2 2 dUTPase Phos_pyr_kin PF08543.7 EEQ78424.1 - 1.3e-12 47.4 0.0 6.4e-12 45.1 0.0 2.0 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EEQ78424.1 - 2.9e-08 33.2 3.5 6.6e-08 32.0 0.1 2.8 2 1 0 2 2 2 1 pfkB family carbohydrate kinase Formyl_trans_N PF00551.14 EEQ78425.1 - 1.6e-38 132.1 0.1 1.9e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase DUF2437 PF10370.4 EEQ78425.1 - 0.1 13.0 0.0 3.8 7.9 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2437) DUF951 PF06107.6 EEQ78425.1 - 0.14 11.7 0.6 0.96 9.0 0.0 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF951) Sporozoite_P67 PF05642.6 EEQ78427.1 - 0.42 8.4 8.0 0.56 7.9 5.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RAP1 PF07218.6 EEQ78427.1 - 2.7 5.9 5.8 3.5 5.6 4.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Afi1 PF07792.7 EEQ78428.1 - 9.6e-63 210.5 0.0 1.7e-62 209.6 0.0 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EEQ78428.1 - 3.7e-37 126.4 0.0 6.4e-37 125.7 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EEQ78428.1 - 9.7e-10 37.4 0.0 0.0017 16.9 0.0 3.8 3 1 1 4 4 4 3 Transport protein Avl9 EF-hand_7 PF13499.1 EEQ78429.1 - 1.1e-13 51.1 2.3 3e-10 40.0 0.1 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EEQ78429.1 - 1.4e-13 49.4 3.0 7.5e-06 25.4 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EEQ78429.1 - 3.2e-12 44.8 4.4 1.7e-05 23.8 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 EEQ78429.1 - 1.9e-09 36.4 6.9 0.00022 20.4 1.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EEQ78429.1 - 6.2e-07 28.9 0.6 0.02 14.4 0.0 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.1 EEQ78429.1 - 0.005 16.7 0.0 0.81 9.6 0.0 2.5 2 1 0 2 2 2 1 EF-hand domain SOG2 PF10428.4 EEQ78429.1 - 0.27 9.8 6.4 0.42 9.2 4.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein RabGAP-TBC PF00566.13 EEQ78430.1 - 2e-30 105.9 0.1 1.8e-25 89.6 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain SET PF00856.23 EEQ78431.1 - 3.7e-06 27.3 0.1 0.013 15.7 0.0 3.2 3 0 0 3 3 3 2 SET domain TPR_9 PF13371.1 EEQ78431.1 - 0.014 15.2 0.6 0.034 13.9 0.4 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-MYND PF01753.13 EEQ78431.1 - 0.016 15.0 6.5 0.016 15.0 4.5 2.2 2 0 0 2 2 2 0 MYND finger Ribonuc_P_40 PF08584.6 EEQ78431.1 - 0.18 10.8 0.0 0.33 9.9 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit WD40 PF00400.27 EEQ78432.1 - 3.8e-23 80.4 16.8 1.1e-07 31.4 0.1 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat HAUS6_N PF14661.1 EEQ78433.1 - 0.04 13.2 2.3 0.069 12.4 1.6 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Desmo_N PF06771.6 EEQ78433.1 - 0.081 12.8 2.6 0.17 11.8 1.8 1.5 1 0 0 1 1 1 0 Viral Desmoplakin N-terminus Glucosamine_iso PF01182.15 EEQ78434.1 - 1.7e-58 197.6 0.0 2e-58 197.3 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Peptidase_C37 PF05416.7 EEQ78437.1 - 0.1 10.8 0.0 0.13 10.5 0.0 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DUF1772 PF08592.6 EEQ78438.1 - 2.9e-32 111.2 6.0 3.7e-32 110.9 4.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) RRM_1 PF00076.17 EEQ78440.1 - 1.5e-16 59.7 0.0 9.9e-11 41.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ78440.1 - 2.9e-13 49.5 0.0 3e-10 39.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ78440.1 - 5.6e-05 22.9 0.0 0.00033 20.4 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EEQ78440.1 - 0.016 14.9 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 MIF4G PF02854.14 EEQ78441.1 - 1.5e-26 93.1 0.1 2.5e-26 92.4 0.1 1.4 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EEQ78441.1 - 1.7e-24 85.7 0.1 4.6e-24 84.2 0.0 1.8 2 0 0 2 2 2 1 MA3 domain DPM2 PF07297.7 EEQ78442.1 - 4.8e-32 110.0 0.9 5.7e-32 109.8 0.6 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EEQ78442.1 - 0.0035 16.9 0.7 0.0036 16.9 0.5 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 EEQ78442.1 - 0.0041 16.9 0.3 0.0041 16.9 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) DUF4083 PF13314.1 EEQ78442.1 - 0.0076 16.0 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4083) HD PF01966.17 EEQ78444.1 - 0.00011 22.1 1.0 0.00025 21.0 0.2 1.9 2 0 0 2 2 2 1 HD domain SpoU_methylas_C PF12105.3 EEQ78444.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal RRS1 PF04939.7 EEQ78444.1 - 0.31 10.4 1.6 4.1 6.8 0.1 2.1 1 1 1 2 2 2 0 Ribosome biogenesis regulatory protein (RRS1) GHMP_kinases_N PF00288.21 EEQ78445.1 - 0.83 9.7 4.8 1 9.4 2.0 2.2 2 1 0 2 2 2 0 GHMP kinases N terminal domain Helicase_C PF00271.26 EEQ78446.1 - 2.5e-19 68.9 0.1 6.8e-19 67.5 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ78446.1 - 3.8e-19 69.2 0.0 7.5e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EEQ78446.1 - 1.6e-18 66.8 0.0 3.1e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_10 PF12846.2 EEQ78446.1 - 0.024 14.0 0.2 0.5 9.7 0.0 2.7 2 2 2 4 4 4 0 AAA-like domain AAA_22 PF13401.1 EEQ78446.1 - 0.034 14.2 0.0 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EEQ78446.1 - 0.056 12.4 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) F_actin_cap_B PF01115.12 EEQ78447.1 - 7.3e-108 359.3 0.0 8.6e-108 359.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Med11 PF10280.4 EEQ78448.1 - 8.4e-35 119.3 0.0 1.1e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein DUF4164 PF13747.1 EEQ78448.1 - 0.046 13.8 0.5 4.8 7.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) WD40 PF00400.27 EEQ78449.1 - 6.4e-57 187.5 23.3 1.3e-10 40.7 0.4 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EEQ78449.1 - 3.2e-46 156.9 0.0 5e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 EEQ78449.1 - 1.1e-06 28.1 0.0 2.3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 LisH Nup160 PF11715.3 EEQ78449.1 - 0.00011 20.5 2.5 0.029 12.4 0.1 3.6 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EEQ78449.1 - 0.0007 18.4 0.1 1.8 7.2 0.0 3.8 2 1 1 3 3 3 2 Nup133 N terminal like Abhydrolase_6 PF12697.2 EEQ78450.1 - 1.9e-22 80.2 0.0 2.9e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ78450.1 - 1.6e-07 31.1 0.0 5.2e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEQ78450.1 - 3.7e-07 29.9 0.0 7.7e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EEQ78450.1 - 0.012 14.8 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EEQ78450.1 - 0.02 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2417 PF10329.4 EEQ78451.1 - 6.2e-86 287.5 0.4 9e-86 287.0 0.3 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 EEQ78451.1 - 6.3e-08 32.7 0.5 1.2e-07 31.8 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family YfzA PF14118.1 EEQ78451.1 - 0.17 11.9 0.0 0.17 11.9 0.0 2.5 2 1 0 2 2 2 0 YfzA-like protein NPL4 PF05021.10 EEQ78452.1 - 1.3e-132 441.6 0.0 1.6e-132 441.3 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EEQ78452.1 - 9.4e-70 232.9 0.1 1.4e-69 232.3 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region Flavodoxin_1 PF00258.20 EEQ78453.1 - 3.4e-09 36.8 0.1 6.2e-09 35.9 0.1 1.6 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 EEQ78453.1 - 5.5e-07 29.2 0.0 6.8e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 EEQ78453.1 - 4.4e-06 26.2 0.0 5.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 EEQ78453.1 - 0.0051 16.1 0.2 0.022 14.1 0.1 1.9 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.2 EEQ78453.1 - 0.042 13.8 0.0 0.18 11.7 0.0 1.8 1 1 1 2 2 2 0 Flavodoxin domain adh_short PF00106.20 EEQ78455.1 - 8e-22 77.9 0.0 1.1e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ78455.1 - 8.7e-08 32.0 0.0 1.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEQ78455.1 - 1.5e-07 31.4 0.0 2.2e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EEQ78455.1 - 0.00061 19.0 0.2 0.0018 17.4 0.1 1.7 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EEQ78455.1 - 0.028 14.4 0.0 0.05 13.6 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 EEQ78455.1 - 0.038 12.8 0.0 0.085 11.7 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Pyr_redox_3 PF13738.1 EEQ78457.1 - 1.7e-21 77.2 0.0 6.6e-21 75.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EEQ78457.1 - 1.3e-11 43.4 0.0 2.9e-11 42.3 0.0 1.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EEQ78457.1 - 3.7e-09 36.7 0.0 0.0033 17.3 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEQ78457.1 - 6.5e-09 35.1 0.0 1.6e-06 27.3 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EEQ78457.1 - 1.5e-08 34.5 0.0 8.5e-07 28.9 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EEQ78457.1 - 3.2e-05 24.2 0.1 0.0064 16.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEQ78457.1 - 0.0012 17.8 0.0 0.34 9.7 0.0 3.1 4 0 0 4 4 4 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EEQ78457.1 - 0.0077 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 EEQ78457.1 - 0.0082 14.6 0.2 7.7 4.8 0.0 3.7 4 0 0 4 4 4 1 HI0933-like protein Thi4 PF01946.12 EEQ78457.1 - 0.028 13.5 0.4 3.3 6.7 0.0 2.5 3 0 0 3 3 3 0 Thi4 family NAD_binding_7 PF13241.1 EEQ78457.1 - 0.07 13.3 0.0 0.48 10.7 0.1 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.19 EEQ78457.1 - 0.097 11.5 0.0 2.1 7.1 0.0 2.4 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.15 EEQ78457.1 - 0.14 12.2 0.0 0.52 10.4 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase CPSase_L_chain PF00289.17 EEQ78457.1 - 0.14 12.2 0.0 3.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain zf-CCCH PF00642.19 EEQ78458.1 - 8.7e-19 66.7 34.0 1.3e-08 34.3 0.6 5.2 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 EEQ78458.1 - 1.3 8.5 6.4 5.2 6.6 0.8 3.2 2 0 0 2 2 2 0 Putative zinc-finger domain LRV_FeS PF05484.6 EEQ78458.1 - 1.6 8.3 18.5 1.1 8.8 0.5 4.9 3 2 2 5 5 5 0 LRV protein FeS4 cluster Glyco_hydro_18 PF00704.23 EEQ78459.1 - 8.8e-61 206.2 0.0 1.1e-60 205.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.3 EEQ78459.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) DUF3712 PF12505.3 EEQ78460.1 - 4.7e-27 94.5 1.1 1.5e-25 89.6 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) DUF1279 PF06916.8 EEQ78460.1 - 0.036 14.3 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) DUF1426 PF07234.6 EEQ78460.1 - 0.058 13.1 0.6 0.11 12.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) adh_short PF00106.20 EEQ78464.1 - 1.7e-16 60.6 0.1 2.5e-16 60.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ78464.1 - 1.1e-08 34.9 0.1 1.9e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 KR domain CRCB PF02537.10 EEQ78464.1 - 0.029 14.2 0.0 0.066 13.0 0.0 1.6 1 0 0 1 1 1 0 CrcB-like protein Shikimate_DH PF01488.15 EEQ78464.1 - 0.042 13.9 0.1 0.084 12.9 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.11 EEQ78465.1 - 9.1e-24 83.8 48.3 2.9e-18 65.7 9.8 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ78465.1 - 5.5e-09 35.1 6.8 5.5e-09 35.1 4.7 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EEQ78465.1 - 2.1e-06 26.2 14.9 7.5e-05 21.1 3.2 2.4 1 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF2583 PF10762.4 EEQ78465.1 - 5.3e-05 23.2 9.4 0.08 13.0 0.4 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF2583) Retrotrans_gag PF03732.12 EEQ78467.1 - 0.018 15.1 1.3 0.02 14.9 0.1 1.7 2 0 0 2 2 2 0 Retrotransposon gag protein UPF0181 PF03701.9 EEQ78467.1 - 4 6.8 7.8 0.66 9.3 1.8 2.4 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0181) Sel1 PF08238.7 EEQ78468.1 - 6.3e-15 55.2 6.6 0.00028 21.4 0.6 4.2 4 0 0 4 4 4 3 Sel1 repeat SnoaL_4 PF13577.1 EEQ78469.1 - 3.2e-19 69.1 0.0 3.8e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain NAD_binding_10 PF13460.1 EEQ78470.1 - 7.8e-13 48.8 0.0 1.6e-11 44.5 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EEQ78470.1 - 1.9e-06 27.2 0.0 2.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Far-17a_AIG1 PF04750.9 EEQ78471.1 - 8.7e-09 34.8 16.1 1.2e-08 34.3 11.2 1.3 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein COX4_pro_2 PF07835.7 EEQ78471.1 - 0.13 12.3 1.9 0.48 10.4 1.3 2.1 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV DUF1776 PF08643.5 EEQ78473.1 - 3.9e-93 311.8 0.0 4.9e-93 311.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) WLM PF08325.5 EEQ78474.1 - 9.5e-59 198.3 0.0 1.6e-58 197.6 0.0 1.4 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 EEQ78474.1 - 2.4e-06 26.5 20.7 6.7e-06 25.0 3.0 3.2 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others SprT-like PF10263.4 EEQ78474.1 - 0.0012 18.5 0.3 0.018 14.7 0.0 2.5 2 0 0 2 2 2 1 SprT-like family DUF45 PF01863.12 EEQ78474.1 - 0.0014 18.4 0.4 0.0035 17.1 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF45 DZR PF12773.2 EEQ78474.1 - 0.032 14.0 10.4 0.24 11.2 7.1 2.2 1 1 1 2 2 2 0 Double zinc ribbon DUF955 PF06114.8 EEQ78474.1 - 0.076 12.7 0.2 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF955) zf-Sec23_Sec24 PF04810.10 EEQ78474.1 - 0.53 9.8 8.1 0.58 9.7 0.0 3.3 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger WD40 PF00400.27 EEQ78475.1 - 5e-72 235.4 26.2 4.6e-10 38.9 0.1 11.4 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.7 EEQ78475.1 - 1.3e-21 76.5 0.0 2.4e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EEQ78475.1 - 2.1e-05 22.8 3.9 0.031 12.4 0.0 5.1 4 2 1 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EEQ78475.1 - 0.001 17.9 5.6 0.3 9.7 0.1 4.8 2 2 0 4 4 4 2 Nup133 N terminal like DUF3312 PF11768.3 EEQ78475.1 - 0.0019 16.5 0.1 0.034 12.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) P34-Arc PF04045.9 EEQ78476.1 - 3.6e-105 350.5 0.0 4.3e-105 350.3 0.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 EEQ78476.1 - 0.061 12.7 0.1 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 ARP2/3 complex 20 kDa subunit (ARPC4) tRNA-synt_2 PF00152.15 EEQ78477.1 - 5.6e-77 258.7 0.2 8.9e-77 258.0 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 EEQ78477.1 - 8.4e-17 60.9 0.0 1.2e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 EEQ78477.1 - 1.3e-07 31.3 0.8 4.9e-07 29.5 0.4 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EEQ78477.1 - 0.0015 17.7 0.9 1.1 8.4 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Abhydrolase_3 PF07859.8 EEQ78478.1 - 1e-10 41.5 0.0 2.7e-10 40.1 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold RRN3 PF05327.6 EEQ78479.1 - 8.6e-170 565.5 0.0 1.4e-169 564.8 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 RecO_C PF02565.10 EEQ78479.1 - 0.12 12.2 0.0 0.75 9.6 0.0 2.2 2 0 0 2 2 2 0 Recombination protein O C terminal Hrs_helical PF12210.3 EEQ78480.1 - 0.014 15.6 0.9 0.022 14.9 0.6 1.3 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF605 PF04652.11 EEQ78480.1 - 8.6 5.6 31.7 13 5.1 21.9 1.2 1 0 0 1 1 1 0 Vta1 like WD40 PF00400.27 EEQ78482.1 - 5e-27 92.7 4.0 1.7e-07 30.8 0.0 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 EEQ78482.1 - 1.6e-05 23.2 3.0 0.0012 17.0 0.1 2.8 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Cmc1 PF08583.5 EEQ78483.1 - 2.2e-14 52.9 5.2 2.5e-14 52.7 3.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Prolamin_like PF05617.6 EEQ78483.1 - 0.027 14.5 0.4 0.033 14.3 0.3 1.2 1 0 0 1 1 1 0 Prolamin-like GCK PF07802.6 EEQ78483.1 - 1.6 8.9 4.4 3.6 7.7 0.6 2.1 1 1 1 2 2 2 0 GCK domain Fcf1 PF04900.7 EEQ78484.1 - 1.1e-09 38.2 0.5 9.5e-05 22.4 0.0 3.1 2 1 0 2 2 2 2 Fcf1 SpoIIE PF07228.7 EEQ78486.1 - 2.1e-05 24.2 0.1 0.0001 22.1 0.0 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EEQ78486.1 - 0.0019 17.6 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 EEQ78486.1 - 0.0048 16.3 0.1 1.3 8.3 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C DUF4219 PF13961.1 EEQ78488.1 - 9.4e-08 31.2 0.6 2.8e-07 29.7 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) UBN2_3 PF14244.1 EEQ78488.1 - 0.00017 21.1 4.1 0.0029 17.1 0.2 2.2 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EEQ78488.1 - 0.014 15.1 0.1 0.014 15.1 0.0 2.2 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EEQ78488.1 - 0.023 14.2 1.6 0.028 13.9 0.0 1.8 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type PEHE PF15275.1 EEQ78488.1 - 0.035 14.5 0.9 0.089 13.2 0.6 1.7 1 0 0 1 1 1 0 PEHE domain DUF229 PF02995.12 EEQ78489.1 - 0.094 11.1 0.1 0.11 10.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF3533 PF12051.3 EEQ78489.1 - 0.18 10.5 2.3 0.2 10.3 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) HLH PF00010.21 EEQ78490.1 - 1.3e-13 50.4 0.1 3.8e-13 48.9 0.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Calc_CGRP_IAPP PF00214.14 EEQ78491.1 - 0.11 12.5 0.5 0.17 11.9 0.3 1.2 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family Etmic-2 PF06670.6 EEQ78491.1 - 0.17 10.5 0.4 0.21 10.2 0.3 1.1 1 0 0 1 1 1 0 Microneme protein Etmic-2 Septin PF00735.13 EEQ78492.1 - 5.6e-12 45.2 0.0 9.3e-09 34.6 0.0 2.2 2 0 0 2 2 2 2 Septin Mg_chelatase PF01078.16 EEQ78492.1 - 0.00098 18.3 0.1 0.013 14.7 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 EEQ78492.1 - 0.0051 16.3 0.0 0.0088 15.5 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 EEQ78492.1 - 0.0059 15.7 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 EEQ78492.1 - 0.016 15.1 0.2 0.092 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Miro PF08477.8 EEQ78492.1 - 0.023 15.2 0.0 0.057 13.9 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein NACHT PF05729.7 EEQ78492.1 - 0.026 14.2 0.1 0.058 13.0 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 EEQ78492.1 - 0.027 14.6 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EEQ78492.1 - 0.028 14.1 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 EEQ78492.1 - 0.03 14.6 0.0 0.082 13.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.8 EEQ78492.1 - 0.041 12.7 0.1 0.069 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PduV-EutP PF10662.4 EEQ78492.1 - 0.065 12.7 0.1 0.36 10.2 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.15 EEQ78492.1 - 0.085 11.5 0.0 0.16 10.6 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Gtr1_RagA PF04670.7 EEQ78492.1 - 0.094 11.8 0.1 5.7 6.0 0.1 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region UPF0079 PF02367.12 EEQ78492.1 - 0.11 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 HSP90 PF00183.13 EEQ78493.1 - 1.3e-257 855.4 34.9 1.6e-257 855.1 24.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EEQ78493.1 - 1.3e-12 47.5 0.4 1.3e-12 47.5 0.3 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EEQ78493.1 - 1.4e-11 44.0 0.1 2.7e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.4 EEQ78493.1 - 0.093 12.5 2.6 0.14 11.9 0.1 2.6 3 0 0 3 3 3 0 Tumour suppressor protein DUF1676 PF07898.8 EEQ78493.1 - 0.11 12.7 0.2 0.11 12.7 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1676) NTF2 PF02136.15 EEQ78494.1 - 6.7e-25 87.7 0.2 1.3e-24 86.8 0.1 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EEQ78494.1 - 2.2e-06 27.2 0.1 3.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ78494.1 - 7.2e-05 22.6 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ78494.1 - 0.00046 19.9 0.0 0.00088 19.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EEQ78494.1 - 0.019 14.8 0.1 0.076 12.8 0.0 2.0 1 0 0 1 1 1 0 RNA binding motif Imm16 PF15565.1 EEQ78494.1 - 0.082 12.7 0.5 10 6.0 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 16 PTR PF12789.2 EEQ78495.1 - 0.1 12.4 1.9 0.31 10.9 1.1 1.6 1 1 0 1 1 1 0 Phage tail repeat like Phage_Gp19 PF09355.5 EEQ78496.1 - 0.041 13.7 0.1 0.048 13.4 0.1 1.2 1 0 0 1 1 1 0 Phage protein Gp19/Gp15/Gp42 Pdase_C33_assoc PF14756.1 EEQ78496.1 - 0.043 13.5 0.9 0.056 13.1 0.6 1.2 1 0 0 1 1 1 0 Peptidase_C33-associated domain Herpes_capsid PF06112.6 EEQ78496.1 - 2.4 8.1 6.6 2.9 7.9 4.6 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein TPR_11 PF13414.1 EEQ78499.1 - 6.6e-07 28.8 5.1 0.033 13.8 0.1 4.4 4 1 0 4 4 4 2 TPR repeat TPR_17 PF13431.1 EEQ78499.1 - 0.0044 17.1 1.4 1.7 9.0 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ78499.1 - 0.039 14.6 7.3 1.2 9.8 0.0 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ78499.1 - 0.14 12.9 7.4 3 8.7 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ78499.1 - 0.99 9.3 7.3 9.2 6.2 1.2 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Nnf1 PF03980.9 EEQ78500.1 - 3.4e-32 110.6 1.1 3.4e-32 110.6 0.8 2.2 3 0 0 3 3 3 1 Nnf1 Apolipoprotein PF01442.13 EEQ78500.1 - 0.0091 15.5 3.7 0.0091 15.5 2.5 2.1 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain COG2 PF06148.6 EEQ78500.1 - 0.025 14.4 3.4 0.097 12.5 1.7 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Dzip-like_N PF13815.1 EEQ78500.1 - 0.055 13.2 0.2 0.055 13.2 0.1 2.1 3 1 0 3 3 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal OmpH PF03938.9 EEQ78500.1 - 0.072 13.0 4.7 0.29 11.0 3.3 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Hormone_1 PF00103.15 EEQ78500.1 - 0.11 11.8 0.3 0.21 10.9 0.2 1.4 1 0 0 1 1 1 0 Somatotropin hormone family IFT57 PF10498.4 EEQ78500.1 - 0.11 11.1 2.1 0.18 10.5 1.5 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TMF_DNA_bd PF12329.3 EEQ78500.1 - 0.12 12.2 8.9 0.054 13.3 1.2 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.7 EEQ78500.1 - 0.15 11.9 1.2 0.31 10.8 0.6 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus bZIP_1 PF00170.16 EEQ78500.1 - 0.16 11.9 6.0 1.9 8.5 2.0 2.6 2 0 0 2 2 2 0 bZIP transcription factor V_ATPase_I PF01496.14 EEQ78500.1 - 0.16 9.8 2.3 0.21 9.4 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.6 EEQ78500.1 - 0.28 11.1 7.2 0.36 10.7 1.1 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.4 EEQ78500.1 - 0.41 10.5 10.6 0.11 12.2 4.3 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ApoLp-III PF07464.6 EEQ78500.1 - 1 9.3 7.3 10 6.1 4.5 2.6 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Nup54 PF13874.1 EEQ78500.1 - 4.1 7.0 10.0 0.078 12.6 1.6 2.0 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Pkinase PF00069.20 EEQ78501.1 - 6.3e-77 258.2 0.0 1.1e-76 257.4 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ78501.1 - 3e-37 128.1 0.0 4.7e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ78501.1 - 4.5e-05 22.5 0.3 0.0011 18.0 0.0 2.6 1 1 1 3 3 3 1 Kinase-like APH PF01636.18 EEQ78501.1 - 0.034 13.8 2.1 0.071 12.8 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EEQ78501.1 - 0.11 11.5 0.1 0.11 11.5 0.1 2.0 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SIR2 PF02146.12 EEQ78502.1 - 2.1e-32 112.2 0.0 4.5e-32 111.2 0.0 1.5 1 1 0 1 1 1 1 Sir2 family Cation_efflux PF01545.16 EEQ78503.1 - 1.5e-60 204.7 0.9 1.8e-60 204.4 0.6 1.1 1 0 0 1 1 1 1 Cation efflux family TrkH PF02386.11 EEQ78503.1 - 0.068 11.7 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Cation transport protein UreE_C PF05194.7 EEQ78503.1 - 4.4 7.4 12.8 11 6.1 0.6 2.7 2 0 0 2 2 2 0 UreE urease accessory protein, C-terminal domain FGGY_C PF02782.11 EEQ78504.1 - 1.3e-33 116.2 0.0 1.4e-32 112.9 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EEQ78504.1 - 1.1e-18 67.4 0.0 1.7e-12 47.1 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Xpo1 PF08389.7 EEQ78505.1 - 2e-40 138.1 4.1 8.4e-39 132.8 0.0 3.4 3 1 1 4 4 4 2 Exportin 1-like protein DUF445 PF04286.7 EEQ78505.1 - 0.26 10.7 4.6 7.1 6.0 1.4 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF445) Esterase PF00756.15 EEQ78506.1 - 2.4e-50 171.3 0.0 2.9e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.4 EEQ78506.1 - 9.8e-07 28.2 0.0 1.3e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 EEQ78506.1 - 2.3e-06 27.4 0.0 3.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEQ78506.1 - 2.8e-05 23.4 0.1 5.3e-05 22.5 0.1 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EEQ78506.1 - 0.00014 21.8 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEQ78506.1 - 0.0028 17.2 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 EEQ78506.1 - 0.0044 15.9 0.0 0.0096 14.8 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.8 EEQ78506.1 - 0.0065 16.0 0.0 0.035 13.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EEQ78506.1 - 0.0073 15.7 0.0 0.012 15.1 0.0 1.5 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase PGAP1 PF07819.8 EEQ78506.1 - 0.015 14.9 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 EEQ78506.1 - 0.018 14.6 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PAF-AH_p_II PF03403.8 EEQ78506.1 - 0.067 11.4 0.0 0.2 9.9 0.0 1.7 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Peptidase_C50 PF03568.12 EEQ78507.1 - 3.2e-116 388.1 0.0 6.2e-116 387.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 EEQ78507.1 - 0.00062 19.6 1.5 5.7 6.9 0.0 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat CHAT PF12770.2 EEQ78507.1 - 0.0012 17.9 0.0 0.06 12.4 0.0 2.5 2 0 0 2 2 2 1 CHAT domain Geminin PF07412.7 EEQ78507.1 - 0.17 11.5 0.2 0.34 10.5 0.1 1.5 1 0 0 1 1 1 0 Geminin Mito_carr PF00153.22 EEQ78510.1 - 3.5e-73 241.3 0.4 2.1e-25 88.2 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EEQ78510.1 - 7.4e-16 58.0 2.2 9.7e-10 38.4 0.2 4.3 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EEQ78510.1 - 1.3e-15 55.8 0.8 9.6e-07 28.1 0.0 6.0 6 0 0 6 6 6 2 EF-hand domain EF-hand_1 PF00036.27 EEQ78510.1 - 2e-15 54.8 0.2 2.1e-06 26.5 0.0 5.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 EEQ78510.1 - 2.1e-11 43.2 0.1 0.63 9.6 0.0 5.1 4 1 1 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.1 EEQ78510.1 - 2.3e-07 29.8 0.7 0.00014 21.0 0.0 4.5 5 0 0 5 5 5 1 EF hand MarR_2 PF12802.2 EEQ78510.1 - 0.13 11.9 0.0 29 4.4 0.0 2.7 2 0 0 2 2 2 0 MarR family PAP1 PF08601.5 EEQ78512.1 - 0.54 9.8 4.8 0.58 9.7 3.3 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Pol_alpha_B_N PF08418.5 EEQ78512.1 - 0.6 9.6 6.8 0.73 9.3 4.7 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Peptidase_M22 PF00814.20 EEQ78513.1 - 3.1e-46 158.0 0.0 4.1e-41 141.2 0.0 3.2 2 1 0 2 2 2 2 Glycoprotease family YycC PF14174.1 EEQ78513.1 - 0.005 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 YycC-like protein Myb_DNA-bind_6 PF13921.1 EEQ78514.1 - 3.7e-10 39.7 1.8 8.9e-10 38.5 1.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEQ78514.1 - 0.05 13.6 0.2 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain Rap1_C PF11626.3 EEQ78514.1 - 0.083 12.7 0.1 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain zf-HC5HC2H_2 PF13832.1 EEQ78517.1 - 3.7e-34 117.0 4.8 3.7e-34 117.0 3.3 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EEQ78517.1 - 3.9e-28 97.4 2.2 3.9e-28 97.4 1.5 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 EEQ78517.1 - 5.5e-25 88.4 0.0 1.1e-24 87.4 0.0 1.6 1 0 0 1 1 1 1 Enhancer of polycomb-like PHD_2 PF13831.1 EEQ78517.1 - 5.3e-14 51.2 3.2 5.3e-14 51.2 2.2 2.5 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 EEQ78517.1 - 1.1e-08 34.6 23.7 5.8e-08 32.3 6.8 2.6 2 0 0 2 2 2 2 PHD-finger zf-RING-like PF08746.6 EEQ78517.1 - 5.8 7.0 22.7 0.027 14.4 4.1 2.5 2 0 0 2 2 2 0 RING-like domain C1_1 PF00130.17 EEQ78517.1 - 8.2 6.2 22.6 0.035 13.8 1.1 2.8 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RRM_1 PF00076.17 EEQ78518.1 - 4.1e-21 74.3 0.0 6.8e-21 73.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ78518.1 - 1.8e-15 56.6 0.0 2.9e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ78518.1 - 3.1e-11 42.9 0.0 4.5e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dpy-30 PF05186.8 EEQ78519.1 - 7e-05 22.2 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif DUF3439 PF11921.3 EEQ78519.1 - 0.2 11.4 3.7 0.074 12.7 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF1421 PF07223.6 EEQ78519.1 - 3.1 7.4 33.0 3.5 7.3 22.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) VRR_NUC PF08774.6 EEQ78520.1 - 1.9e-18 66.3 0.1 9e-18 64.1 0.0 2.2 2 0 0 2 2 2 1 VRR-NUC domain Ribosomal_S13_N PF08069.7 EEQ78521.1 - 5.7e-29 99.7 0.1 1.1e-28 98.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EEQ78521.1 - 2.4e-22 78.4 0.0 3.4e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 EEQ78521.1 - 0.013 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain Pkinase PF00069.20 EEQ78523.1 - 9.7e-10 38.0 0.0 1.8e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ78523.1 - 0.006 15.6 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEQ78523.1 - 0.0096 15.6 0.0 0.086 12.5 0.0 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family APH PF01636.18 EEQ78525.1 - 1.5e-12 47.8 0.0 1e-11 45.0 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ78525.1 - 0.019 14.5 0.0 0.05 13.1 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 EEQ78525.1 - 0.13 11.4 0.0 0.68 9.0 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain Birna_VP5 PF03042.9 EEQ78526.1 - 0.012 15.1 0.1 0.015 14.8 0.1 1.1 1 0 0 1 1 1 0 Birnavirus VP5 protein CENP-F_leu_zip PF10473.4 EEQ78526.1 - 0.022 14.5 2.4 3.6 7.4 1.3 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ApoL PF05461.6 EEQ78526.1 - 0.038 13.2 1.7 0.042 13.1 1.2 1.0 1 0 0 1 1 1 0 Apolipoprotein L CBP4 PF07960.6 EEQ78526.1 - 0.091 12.3 1.1 0.11 12.0 0.7 1.2 1 0 0 1 1 1 0 CBP4 SecD-TM1 PF13721.1 EEQ78526.1 - 0.15 12.3 2.8 0.18 12.0 1.5 1.4 1 1 0 1 1 1 0 SecD export protein N-terminal TM region NPV_P10 PF05531.7 EEQ78526.1 - 0.2 11.9 2.6 4.3 7.6 1.8 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Enkurin PF13864.1 EEQ78526.1 - 0.28 11.4 2.6 0.38 10.9 1.8 1.2 1 0 0 1 1 1 0 Calmodulin-binding APG6 PF04111.7 EEQ78526.1 - 0.36 9.8 4.2 0.41 9.6 2.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 V-SNARE_C PF12352.3 EEQ78526.1 - 0.5 10.4 3.6 0.38 10.8 0.5 2.2 1 1 1 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Tup_N PF08581.5 EEQ78526.1 - 1.1 9.5 6.2 5 7.3 1.5 2.3 1 1 0 2 2 2 0 Tup N-terminal IncA PF04156.9 EEQ78526.1 - 2.8 7.5 7.1 2.8 7.4 5.0 1.2 1 1 0 1 1 1 0 IncA protein T2SM PF04612.7 EEQ78526.1 - 3 7.6 9.9 2.5 7.8 4.3 1.9 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M DivIC PF04977.10 EEQ78526.1 - 7.9 6.0 8.3 27 4.3 0.1 2.4 1 1 1 2 2 2 0 Septum formation initiator ABC_tran PF00005.22 EEQ78527.1 - 4.7e-15 56.0 0.0 1.9e-14 54.1 0.0 2.0 1 1 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EEQ78527.1 - 0.00061 19.2 4.3 0.00061 19.2 2.9 1.7 1 1 1 2 2 2 1 ABC transporter transmembrane region Chromate_transp PF02417.10 EEQ78528.1 - 1.6e-53 180.7 24.3 1.1e-28 99.9 8.6 2.3 2 0 0 2 2 2 2 Chromate transporter DUF4658 PF15555.1 EEQ78530.1 - 0.12 12.2 1.0 0.18 11.6 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) RRM_1 PF00076.17 EEQ78533.1 - 9.3e-35 118.0 0.2 9.1e-14 50.8 0.0 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ78533.1 - 1.5e-24 85.7 0.0 3.8e-07 29.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ78533.1 - 9.8e-16 57.3 0.1 1.4e-07 31.2 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OGG_N PF07934.7 EEQ78534.1 - 1.2e-37 128.4 0.0 2.1e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EEQ78534.1 - 1.2e-15 57.7 0.0 2.1e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EEQ78534.1 - 0.046 13.4 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif Zn_clus PF00172.13 EEQ78535.1 - 5.9e-08 32.4 14.6 1.2e-07 31.5 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rax2 PF12768.2 EEQ78536.1 - 1.4e-95 319.7 0.0 2.6e-90 302.4 0.0 4.4 3 2 1 4 4 4 4 Cortical protein marker for cell polarity Pro_CA PF00484.14 EEQ78537.1 - 1.2e-48 164.9 0.0 1.6e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase SSrecog PF03531.9 EEQ78539.1 - 7.1e-71 238.0 0.9 7.3e-70 234.7 0.6 2.2 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EEQ78539.1 - 2.4e-27 94.7 0.1 2.5e-26 91.4 0.0 2.3 2 0 0 2 2 2 1 Histone chaperone Rttp106-like SAP PF02037.22 EEQ78540.1 - 4.5e-12 45.1 0.1 1e-11 44.0 0.1 1.6 1 0 0 1 1 1 1 SAP domain Methyltransf_11 PF08241.7 EEQ78542.1 - 0.15 12.5 0.0 0.4 11.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain SF3b1 PF08920.5 EEQ78543.1 - 2.6e-45 154.0 7.6 3.2e-44 150.5 0.4 2.3 1 1 1 2 2 2 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EEQ78543.1 - 2.8e-15 56.3 3.9 0.011 16.0 0.0 7.5 7 2 1 8 8 8 5 HEAT repeats HEAT PF02985.17 EEQ78543.1 - 2.3e-10 39.6 9.7 1 9.6 0.0 9.3 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.1 EEQ78543.1 - 1.8e-09 37.8 4.4 0.54 10.8 0.0 7.6 6 2 2 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EEQ78543.1 - 5.9e-06 26.5 0.2 0.94 9.8 0.0 5.6 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EEQ78543.1 - 0.00073 17.9 0.2 0.6 8.3 0.0 3.4 3 1 0 3 3 3 2 Adaptin N terminal region NUC173 PF08161.7 EEQ78543.1 - 0.0043 16.4 0.7 4.2 6.6 0.0 3.9 4 0 0 4 4 4 1 NUC173 domain CLASP_N PF12348.3 EEQ78543.1 - 0.015 14.7 0.8 1 8.6 0.0 3.4 4 0 0 4 4 4 0 CLASP N terminal CRM1_C PF08767.6 EEQ78543.1 - 0.19 10.5 0.4 0.8 8.5 0.1 2.1 2 0 0 2 2 2 0 CRM1 C terminal DUF2890 PF11081.3 EEQ78543.1 - 2.3 8.2 13.3 3.9 7.4 8.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) zf-met PF12874.2 EEQ78546.1 - 5.9e-06 26.2 1.5 2e-05 24.6 1.0 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EEQ78546.1 - 2e-05 24.6 4.5 2e-05 24.6 3.1 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EEQ78546.1 - 0.00012 22.1 2.1 0.00012 22.1 1.4 2.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EEQ78546.1 - 0.0002 21.4 2.3 0.0002 21.4 1.6 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EEQ78546.1 - 0.004 17.0 1.5 0.004 17.0 1.1 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EEQ78546.1 - 0.02 15.1 28.6 0.047 14.0 1.1 3.9 4 0 0 4 4 4 0 Zinc-finger double domain APC_CDC26 PF10471.4 EEQ78546.1 - 0.89 10.3 7.7 3 8.6 5.3 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 zf-BED PF02892.10 EEQ78546.1 - 1.3 8.8 6.9 8.2 6.2 4.8 2.1 1 1 0 1 1 1 0 BED zinc finger Fungal_trans PF04082.13 EEQ78547.1 - 1.9e-07 30.2 0.1 3.5e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ78547.1 - 6.5e-06 25.9 9.4 1.2e-05 25.1 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec1 PF00995.18 EEQ78549.1 - 4.7e-130 434.8 0.0 5.4e-130 434.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Telomere_reg-2 PF10193.4 EEQ78550.1 - 2e-33 115.0 0.0 4.5e-33 113.8 0.0 1.7 1 0 0 1 1 1 1 Telomere length regulation protein ThiF PF00899.16 EEQ78551.1 - 4.4e-36 123.7 0.2 1.1e-35 122.4 0.0 1.6 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 EEQ78551.1 - 2.8e-25 87.8 0.1 4.9e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 EEQ78551.1 - 1.5e-24 85.3 0.6 3.1e-24 84.3 0.4 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EEQ78551.1 - 5.6e-14 51.2 3.1 5.6e-14 51.2 2.1 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 EEQ78551.1 - 0.0007 19.1 0.0 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain Ecm33 PF12454.3 EEQ78551.1 - 0.045 13.6 2.3 0.093 12.6 1.6 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein RNA_pol_A_bac PF01000.21 EEQ78552.1 - 7.9e-27 93.6 0.0 1.5e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EEQ78552.1 - 8.7e-13 47.1 0.0 1.1e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.14 EEQ78553.1 - 8.5e-135 448.0 0.0 1.1e-134 447.6 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit UQ_con PF00179.21 EEQ78554.1 - 1.2e-23 83.1 2.7 2.2e-23 82.2 1.9 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EEQ78554.1 - 0.0001 22.1 0.5 0.00021 21.1 0.4 1.6 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 EEQ78554.1 - 0.0018 18.0 0.0 0.0071 16.1 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic E2 family B SSP160 PF06933.6 EEQ78554.1 - 3.5 5.4 8.3 4 5.2 5.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pkinase PF00069.20 EEQ78556.1 - 3.7e-69 232.7 0.0 4.8e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ78556.1 - 3.3e-34 118.1 0.1 5.2e-34 117.4 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ78556.1 - 0.00053 19.0 0.0 0.00081 18.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EEQ78556.1 - 0.0044 16.3 0.0 0.012 15.0 0.0 1.7 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EEQ78556.1 - 0.01 14.9 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Macoilin PF09726.4 EEQ78557.1 - 3.1 5.9 16.8 4.8 5.3 11.7 1.2 1 0 0 1 1 1 0 Transmembrane protein Apt1 PF10351.4 EEQ78557.1 - 8.2 5.1 10.6 13 4.5 7.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pkinase PF00069.20 EEQ78558.1 - 1.2e-54 185.2 0.0 1.6e-54 184.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ78558.1 - 3.2e-39 134.5 0.0 4.8e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEQ78558.1 - 1.5e-05 24.1 0.0 2.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEQ78558.1 - 0.0087 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EEQ78558.1 - 0.017 14.1 0.1 0.039 13.0 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EEQ78558.1 - 0.02 14.2 0.9 0.36 10.1 0.6 2.2 1 1 0 1 1 1 0 RIO1 family Aminotran_1_2 PF00155.16 EEQ78559.1 - 2.5e-16 59.6 0.0 3.2e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EEQ78559.1 - 0.00066 18.3 0.0 0.0021 16.7 0.0 1.7 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 EEQ78559.1 - 0.0057 15.7 0.0 0.043 12.8 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_trans PF04082.13 EEQ78560.1 - 1.4e-25 89.6 0.0 8e-25 87.1 0.0 2.0 1 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ78560.1 - 1.7e-09 37.4 14.0 3.3e-09 36.4 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prefoldin_2 PF01920.15 EEQ78561.1 - 1.5e-24 85.8 5.7 1.7e-24 85.6 3.9 1.0 1 0 0 1 1 1 1 Prefoldin subunit DASH_Dad3 PF08656.5 EEQ78561.1 - 0.0022 17.6 2.2 0.0058 16.2 0.5 2.0 2 0 0 2 2 2 1 DASH complex subunit Dad3 Prefoldin PF02996.12 EEQ78561.1 - 0.0037 16.8 3.8 0.68 9.5 0.0 2.2 2 0 0 2 2 2 2 Prefoldin subunit DUF641 PF04859.7 EEQ78561.1 - 0.0063 16.2 1.3 1.4 8.6 0.0 2.0 1 1 1 2 2 2 1 Plant protein of unknown function (DUF641) Troponin PF00992.15 EEQ78561.1 - 0.0082 16.1 3.5 0.6 10.1 0.0 2.0 2 0 0 2 2 2 2 Troponin PEPcase_2 PF14010.1 EEQ78561.1 - 0.0086 14.4 0.1 0.027 12.8 0.0 1.6 1 1 1 2 2 2 1 Phosphoenolpyruvate carboxylase KaiC PF06745.8 EEQ78561.1 - 0.022 13.8 0.4 0.15 11.1 0.1 1.9 1 1 1 2 2 2 0 KaiC GAS PF13851.1 EEQ78561.1 - 0.061 12.5 7.0 0.21 10.7 4.9 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding FliJ PF02050.11 EEQ78561.1 - 0.071 13.1 7.3 0.63 10.1 2.7 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein Scm3 PF10384.4 EEQ78561.1 - 0.077 12.4 1.5 2.2 7.8 0.5 2.2 2 0 0 2 2 2 0 Centromere protein Scm3 HrpB7 PF09486.5 EEQ78561.1 - 0.15 12.0 0.7 0.71 9.7 0.5 1.9 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) OmpH PF03938.9 EEQ78561.1 - 0.16 11.8 7.5 0.16 11.8 2.5 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Tho2 PF11262.3 EEQ78561.1 - 0.17 10.9 3.2 4.3 6.3 1.5 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 PEP-utilisers_N PF05524.8 EEQ78561.1 - 0.17 11.7 0.7 0.42 10.4 0.5 1.7 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal bZIP_Maf PF03131.12 EEQ78561.1 - 0.18 12.1 4.3 4 7.7 1.8 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor TroA PF01297.12 EEQ78561.1 - 0.21 10.7 2.6 0.27 10.4 0.7 1.7 2 0 0 2 2 2 0 Periplasmic solute binding protein family Cytochrom_B562 PF07361.6 EEQ78561.1 - 0.22 11.9 5.4 0.36 11.2 1.5 2.0 2 0 0 2 2 2 0 Cytochrome b562 DUF2205 PF10224.4 EEQ78561.1 - 0.23 11.0 4.1 0.15 11.6 0.7 2.0 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Syntaxin-6_N PF09177.6 EEQ78561.1 - 0.24 11.8 1.8 0.66 10.4 0.4 1.9 2 0 0 2 2 2 0 Syntaxin 6, N-terminal STAT_alpha PF01017.15 EEQ78561.1 - 0.38 10.4 6.7 0.66 9.6 4.6 1.4 1 1 0 1 1 1 0 STAT protein, all-alpha domain FTA4 PF13093.1 EEQ78561.1 - 0.44 9.9 4.7 0.83 9.0 3.3 1.6 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4140 PF13600.1 EEQ78561.1 - 0.69 10.3 4.0 7.4 7.0 1.6 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Seryl_tRNA_N PF02403.17 EEQ78561.1 - 0.94 9.5 6.3 1.4 9.0 1.1 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3298 PF11738.3 EEQ78561.1 - 1.8 9.1 4.6 2.9 8.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3298) IncA PF04156.9 EEQ78561.1 - 4.1 6.9 10.0 15 5.0 6.8 1.8 1 1 0 1 1 1 0 IncA protein AKNA PF12443.3 EEQ78561.1 - 5 7.1 7.8 8 6.5 2.4 2.1 2 0 0 2 2 2 0 AT-hook-containing transcription factor Spc24 PF08286.6 EEQ78561.1 - 5.6 6.6 8.3 53 3.5 5.8 2.0 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 CBFD_NFYB_HMF PF00808.18 EEQ78563.1 - 8.8e-30 102.5 0.9 1.2e-29 102.1 0.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEQ78563.1 - 3.6e-07 30.1 0.0 5.4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EEQ78563.1 - 0.00068 19.3 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EEQ78563.1 - 0.0011 18.7 0.1 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 EEQ78563.1 - 0.046 13.9 0.1 0.084 13.1 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A HA2 PF04408.18 EEQ78564.1 - 3.7e-24 84.6 0.2 1.7e-23 82.5 0.0 2.4 3 0 0 3 3 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EEQ78564.1 - 6.9e-24 83.8 0.0 5.9e-22 77.6 0.0 2.6 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EEQ78564.1 - 1.1e-13 50.7 0.0 2.8e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEQ78564.1 - 7.7e-08 32.0 0.1 1.5e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEQ78564.1 - 0.00028 21.0 0.1 0.00071 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EEQ78564.1 - 0.0015 18.4 0.0 0.69 9.7 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EEQ78564.1 - 0.0017 17.3 0.0 0.0038 16.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 EEQ78564.1 - 0.0082 16.0 0.1 0.058 13.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 EEQ78564.1 - 0.011 15.2 0.4 0.026 13.9 0.3 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain KaiC PF06745.8 EEQ78564.1 - 0.018 14.1 0.1 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF2075 PF09848.4 EEQ78564.1 - 0.019 13.9 0.0 0.036 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 EEQ78564.1 - 0.021 14.5 0.4 0.51 9.9 0.1 2.5 3 0 0 3 3 2 0 NACHT domain Flavi_DEAD PF07652.9 EEQ78564.1 - 0.07 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain NB-ARC PF00931.17 EEQ78564.1 - 0.1 11.4 0.0 0.23 10.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain DUF1570 PF07607.6 EEQ78564.1 - 0.36 10.8 3.2 3.3 7.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1570) G-alpha PF00503.15 EEQ78564.1 - 2.4 6.7 5.1 0.21 10.2 0.1 1.7 2 0 0 2 2 2 0 G-protein alpha subunit DAD PF02109.11 EEQ78565.1 - 2e-40 137.3 1.1 3.3e-39 133.4 0.7 2.0 1 1 0 1 1 1 1 DAD family Tmemb_14 PF03647.8 EEQ78566.1 - 5.5e-24 84.3 6.6 7.7e-24 83.9 4.5 1.2 1 0 0 1 1 1 1 Transmembrane proteins 14C Rpp20 PF12328.3 EEQ78566.1 - 0.014 15.0 0.1 0.029 14.0 0.0 1.5 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P RTC4 PF14474.1 EEQ78567.1 - 2.7e-39 133.9 0.0 4.3e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain DUF726 PF05277.7 EEQ78568.1 - 1.2e-127 425.5 3.1 1.7e-127 425.1 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Lipase_3 PF01764.20 EEQ78568.1 - 0.066 12.8 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) UPF0565 PF10561.4 EEQ78568.1 - 0.096 11.5 0.0 0.21 10.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 p450 PF00067.17 EEQ78571.1 - 1.6e-65 221.4 0.0 2e-65 221.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EEQ78573.1 - 6.4e-33 113.9 38.5 1.6e-31 109.3 10.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ78573.1 - 6.6e-09 34.8 5.0 6.6e-09 34.8 3.5 3.2 2 2 2 4 4 4 1 Sugar (and other) transporter MFS_2 PF13347.1 EEQ78573.1 - 4.7e-05 21.9 3.8 4.7e-05 21.9 2.6 2.8 2 2 1 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.2 EEQ78573.1 - 0.054 13.3 2.4 1.2 8.9 0.0 3.3 3 1 1 4 4 4 0 MFS_1 like family MFS_3 PF05977.8 EEQ78573.1 - 0.89 7.5 6.1 0.082 11.0 1.0 1.5 2 0 0 2 2 2 0 Transmembrane secretion effector Peptidase_M28 PF04389.12 EEQ78574.1 - 4.5e-18 65.6 0.2 4.4e-17 62.3 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M28 TFR_dimer PF04253.10 EEQ78574.1 - 4.1e-17 61.9 0.1 7.9e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 EEQ78574.1 - 1.8e-07 30.7 0.0 3.9e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 EEQ78574.1 - 0.0034 16.6 0.5 0.0061 15.8 0.0 1.6 2 0 0 2 2 2 1 Nicastrin zf-C2H2_4 PF13894.1 EEQ78575.1 - 0.0011 19.1 1.3 0.08 13.3 0.0 2.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EEQ78575.1 - 0.0016 18.6 3.0 0.045 14.0 0.1 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-Di19 PF05605.7 EEQ78575.1 - 0.15 12.2 0.6 4 7.6 0.4 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EEQ78575.1 - 0.16 12.1 1.5 13 6.1 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EEQ78575.1 - 0.31 10.9 2.8 6.8 6.7 0.0 2.5 1 1 1 2 2 2 0 C2H2-type zinc finger CMD PF02627.15 EEQ78577.1 - 2.3e-09 36.9 0.0 3.7e-07 29.9 0.0 2.4 2 1 0 2 2 2 2 Carboxymuconolactone decarboxylase family TPR_14 PF13428.1 EEQ78577.1 - 0.078 13.6 0.0 0.21 12.3 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat UBN2 PF14223.1 EEQ78578.1 - 1.7e-05 24.5 0.0 5.6e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EEQ78578.1 - 0.00018 21.1 0.8 0.00036 20.1 0.6 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 EEQ78578.1 - 0.0054 16.6 4.8 0.0092 15.8 3.3 1.4 1 0 0 1 1 1 1 Zinc knuckle UBN2_2 PF14227.1 EEQ78578.1 - 0.014 14.9 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DegS PF05384.6 EEQ78578.1 - 0.086 12.0 1.0 0.44 9.7 0.0 2.2 2 0 0 2 2 2 0 Sensor protein DegS DUF2413 PF10310.4 EEQ78579.1 - 1.3e-142 475.7 0.0 1.5e-142 475.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 EEQ78579.1 - 0.054 13.5 1.0 0.15 12.0 0.1 2.1 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain SurE PF01975.12 EEQ78580.1 - 5.5e-42 143.2 0.0 9.4e-42 142.5 0.0 1.4 1 0 0 1 1 1 1 Survival protein SurE DUF2462 PF09495.5 EEQ78583.1 - 2.4e-21 76.2 8.4 2.4e-21 76.2 5.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) Macoilin PF09726.4 EEQ78584.1 - 0.43 8.8 10.7 0.073 11.3 4.8 1.6 2 0 0 2 2 2 0 Transmembrane protein Allexi_40kDa PF05549.6 EEQ78584.1 - 4.7 6.4 10.4 0.47 9.6 2.0 2.5 2 1 0 2 2 2 0 Allexivirus 40kDa protein GPI-anchored PF10342.4 EEQ78585.1 - 2.7e-22 79.0 0.1 2.7e-22 79.0 0.1 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Aldedh PF00171.17 EEQ78586.1 - 6.4e-131 436.8 0.0 7.8e-131 436.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cellulase PF00150.13 EEQ78587.1 - 9.8e-16 57.7 0.1 9.8e-16 57.7 0.1 1.3 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 EEQ78587.1 - 0.077 12.0 0.1 8.3 5.4 0.0 2.2 1 1 1 2 2 2 0 Beta-galactosidase IBN_N PF03810.14 EEQ78588.1 - 1.6e-16 60.0 1.8 9.9e-14 51.0 0.1 4.0 4 0 0 4 4 4 2 Importin-beta N-terminal domain Pex2_Pex12 PF04757.9 EEQ78589.1 - 1.4e-37 129.2 1.1 1.8e-37 128.9 0.8 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EEQ78589.1 - 0.0029 17.4 5.0 0.0029 17.4 3.5 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EEQ78589.1 - 0.072 13.1 9.0 0.29 11.1 3.5 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EEQ78589.1 - 0.092 12.4 2.2 0.82 9.4 1.6 2.3 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.1 EEQ78589.1 - 0.55 10.1 6.8 16 5.3 2.2 2.6 2 1 0 2 2 2 0 Ring finger domain MFS_1 PF07690.11 EEQ78591.1 - 1.3e-31 109.6 24.7 3.6e-31 108.1 17.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily APH PF01636.18 EEQ78593.1 - 9.1e-08 32.1 0.0 0.00011 21.9 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family HipA_N PF07805.7 EEQ78593.1 - 0.09 13.0 0.0 1.9 8.7 0.0 2.3 1 1 1 2 2 2 0 HipA-like N-terminal domain Choline_kinase PF01633.15 EEQ78594.1 - 0.00017 21.1 0.0 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EEQ78594.1 - 0.02 14.6 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EEQ78594.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ILVD_EDD PF00920.16 EEQ78595.1 - 3.7e-204 678.9 5.1 4.2e-204 678.7 3.5 1.0 1 0 0 1 1 1 1 Dehydratase family InvH PF04741.7 EEQ78595.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 InvH outer membrane lipoprotein Abhydrolase_6 PF12697.2 EEQ78596.1 - 4.7e-23 82.2 0.0 1.2e-22 80.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEQ78596.1 - 3.3e-13 49.6 0.0 1.7e-12 47.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.15 EEQ78596.1 - 3.4e-10 39.6 0.0 1e-09 38.0 0.0 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.15 EEQ78596.1 - 2.5e-09 37.0 0.0 4.6e-08 32.9 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold PTPlike_phytase PF14566.1 EEQ78596.1 - 2.5e-05 24.3 0.0 4.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Ser_hydrolase PF06821.8 EEQ78596.1 - 0.00025 20.7 0.0 0.0009 18.8 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase DUF2305 PF10230.4 EEQ78596.1 - 0.0067 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Y_phosphatase PF00102.22 EEQ78596.1 - 0.019 14.2 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PGAP1 PF07819.8 EEQ78596.1 - 0.032 13.7 0.1 0.29 10.6 0.1 2.2 1 1 0 1 1 1 0 PGAP1-like protein LCAT PF02450.10 EEQ78596.1 - 0.054 12.4 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 EEQ78596.1 - 0.07 12.4 0.0 0.17 11.1 0.0 1.6 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.3 EEQ78596.1 - 0.13 12.0 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase DUF1749 PF08538.5 EEQ78596.1 - 0.15 10.9 0.0 0.44 9.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Ribosomal_S19e PF01090.14 EEQ78597.1 - 4.9e-56 188.0 0.1 5.6e-56 187.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Prim-Pol PF09250.6 EEQ78597.1 - 0.025 14.5 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal Aldo_ket_red PF00248.16 EEQ78599.1 - 3.6e-43 147.4 0.0 6.3e-43 146.6 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family eRF1_1 PF03463.10 EEQ78600.1 - 1e-47 160.9 0.1 1.7e-47 160.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 EEQ78600.1 - 4.4e-19 68.8 0.0 9.1e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 EEQ78600.1 - 1.1e-18 67.8 0.0 2.3e-18 66.8 0.0 1.5 1 1 0 1 1 1 1 eRF1 domain 2 Myb_DNA-bind_4 PF13837.1 EEQ78601.1 - 0.0001 22.3 2.7 0.015 15.4 0.1 2.7 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EEQ78601.1 - 0.0034 17.2 0.4 0.38 10.6 0.2 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain HTH_32 PF13565.1 EEQ78601.1 - 0.0036 18.0 1.8 0.0093 16.7 1.3 1.7 1 0 0 1 1 1 1 Homeodomain-like domain Myb_DNA-bind_3 PF12776.2 EEQ78601.1 - 0.04 14.5 0.9 5.3 7.7 0.1 2.4 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEQ78602.1 - 6.2e-05 23.0 0.5 0.0049 16.9 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEQ78602.1 - 0.015 15.3 3.1 0.057 13.4 2.2 2.0 2 1 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEQ78605.1 - 1.5e-12 47.3 5.2 5.3e-07 29.5 1.7 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEQ78605.1 - 7.9e-11 41.9 1.4 3.9e-06 26.8 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain PAT1 PF09770.4 EEQ78605.1 - 4.5 5.3 6.5 5.2 5.1 4.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 COX5B PF01215.14 EEQ78607.1 - 7.3e-36 122.8 0.0 1e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.14 EEQ78607.1 - 0.078 12.5 0.3 0.7 9.4 0.0 2.1 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Myb_DNA-bind_6 PF13921.1 EEQ78608.1 - 1.4e-12 47.4 0.0 1.6e-07 31.3 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEQ78608.1 - 1.7e-12 47.1 0.1 2.5e-05 24.2 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain CDK2AP PF09806.4 EEQ78608.1 - 0.33 11.1 9.6 0.22 11.7 2.8 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Androgen_recep PF02166.11 EEQ78608.1 - 0.45 9.3 19.4 0.63 8.8 13.4 1.2 1 0 0 1 1 1 0 Androgen receptor PROCN PF08083.6 EEQ78611.1 - 1.8e-223 741.4 6.3 2.9e-223 740.7 4.4 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EEQ78611.1 - 3.1e-126 419.3 2.2 5.3e-126 418.5 1.5 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EEQ78611.1 - 3.5e-103 341.7 0.2 3.5e-63 211.7 0.1 2.6 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EEQ78611.1 - 1.5e-77 258.4 3.4 1.5e-77 258.4 1.2 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EEQ78611.1 - 1.7e-66 221.9 0.2 3.7e-66 220.8 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 Hom_end_hint PF05203.11 EEQ78611.1 - 2.4e-58 197.4 0.0 1.7e-55 188.1 0.0 3.3 2 1 0 2 2 2 1 Hom_end-associated Hint PROCT PF08084.6 EEQ78611.1 - 4.3e-46 155.6 0.7 9.5e-46 154.5 0.1 2.0 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.4 EEQ78611.1 - 5.1e-45 151.2 0.2 1.4e-44 149.8 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Hom_end PF05204.9 EEQ78611.1 - 1.1e-06 28.5 0.0 3.3e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 Homing endonuclease Hint_2 PF13403.1 EEQ78611.1 - 0.027 14.4 0.1 0.1 12.5 0.1 2.0 1 1 0 1 1 1 0 Hint domain DUF3753 PF12575.3 EEQ78611.1 - 0.17 11.7 0.0 0.45 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) OCD_Mu_crystall PF02423.10 EEQ78611.1 - 0.38 9.4 1.6 0.69 8.6 1.1 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Ribosomal_L34e PF01199.13 EEQ78612.1 - 4.5e-37 126.1 4.1 6.5e-37 125.6 2.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e PDGF PF00341.12 EEQ78612.1 - 0.074 13.1 0.1 0.074 13.1 0.1 1.7 2 1 0 2 2 2 0 PDGF/VEGF domain Fork_head PF00250.13 EEQ78614.1 - 1.9e-15 56.6 0.4 3.5e-15 55.8 0.3 1.4 1 0 0 1 1 1 1 Fork head domain Cactin_mid PF10312.4 EEQ78615.1 - 5.5e-67 224.7 2.6 7.7e-67 224.2 1.8 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EEQ78615.1 - 1.6e-48 163.3 5.9 2.9e-48 162.5 4.1 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein XLF PF09302.6 EEQ78616.1 - 3.2e-28 98.6 0.3 5.3e-28 97.9 0.2 1.4 1 0 0 1 1 1 1 XLF (XRCC4-like factor) WD40 PF00400.27 EEQ78617.1 - 1.8e-13 49.7 13.5 3.5e-06 26.6 0.0 6.6 6 1 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EEQ78617.1 - 0.014 15.1 0.0 7.1 6.2 0.0 2.7 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A ABC_tran PF00005.22 EEQ78619.1 - 2.1e-31 109.0 0.0 4.5e-31 107.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EEQ78619.1 - 4e-30 105.1 13.1 9.3e-30 103.9 9.1 1.7 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EEQ78619.1 - 8.4e-07 28.4 0.0 2.8e-05 23.4 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEQ78619.1 - 0.00015 21.8 0.0 0.052 13.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 EEQ78619.1 - 0.0037 17.1 0.2 0.035 14.0 0.1 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 EEQ78619.1 - 0.0037 17.2 0.2 0.014 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EEQ78619.1 - 0.014 14.8 0.1 0.038 13.5 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EEQ78619.1 - 0.017 14.2 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEQ78619.1 - 0.033 14.3 0.2 0.29 11.2 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EEQ78619.1 - 0.067 12.9 0.1 0.79 9.4 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF498 PF04430.9 EEQ78620.1 - 2.4e-27 94.6 0.0 3.9e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Alk_phosphatase PF00245.15 EEQ78621.1 - 1.4e-110 369.8 0.0 1.7e-110 369.5 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EEQ78621.1 - 0.00015 21.2 0.0 0.0003 20.2 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF754 PF05449.6 EEQ78621.1 - 0.052 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF754) Glyco_hydro_16 PF00722.16 EEQ78623.1 - 1.4e-42 145.1 3.2 2e-42 144.6 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Pro_dh PF01619.13 EEQ78625.1 - 7.2e-31 107.3 2.8 7.4e-22 77.7 0.2 2.4 2 1 0 2 2 2 2 Proline dehydrogenase AP-5_subunit_s1 PF15001.1 EEQ78625.1 - 0.084 12.8 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 B1 PF02246.10 EEQ78625.1 - 0.21 11.4 0.9 0.62 9.9 0.5 1.8 2 0 0 2 2 2 0 Protein L b1 domain Trypan_PARP PF05887.6 EEQ78625.1 - 0.48 10.2 8.7 1 9.1 6.1 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) KAR9 PF08580.5 EEQ78625.1 - 9.3 4.3 7.4 2.5 6.2 2.8 1.6 2 0 0 2 2 2 0 Yeast cortical protein KAR9 PMSR PF01625.16 EEQ78627.1 - 2.1e-59 199.8 0.1 2.4e-59 199.7 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Kinesin PF00225.18 EEQ78628.1 - 3.8e-117 390.7 0.1 6.1e-117 390.0 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain AAA_33 PF13671.1 EEQ78628.1 - 0.0087 15.9 0.0 0.044 13.6 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EEQ78628.1 - 1.3 9.3 6.3 0.18 12.0 0.5 2.4 2 0 0 2 2 2 0 AAA domain DUF4013 PF13197.1 EEQ78631.1 - 0.0044 16.3 0.3 0.0067 15.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4013) cNMP_binding PF00027.24 EEQ78632.1 - 5.9e-38 128.5 0.0 2.1e-19 69.1 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 EEQ78632.1 - 2.4e-12 45.5 19.8 0.07 13.2 0.1 10.3 10 0 0 10 10 10 2 Leucine Rich repeat F-box PF00646.28 EEQ78632.1 - 1e-06 28.2 3.5 9e-06 25.2 1.0 3.0 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.28 EEQ78632.1 - 4.7e-05 22.8 17.7 15 6.1 0.0 10.0 10 1 1 11 11 11 0 Leucine Rich Repeat LRR_8 PF13855.1 EEQ78632.1 - 0.00013 21.6 5.3 0.003 17.2 0.4 4.8 4 1 3 7 7 7 1 Leucine rich repeat F-box-like PF12937.2 EEQ78632.1 - 0.0025 17.5 1.3 0.0082 15.8 0.4 2.3 3 0 0 3 3 3 1 F-box-like Ste50p-SAM PF09235.5 EEQ78632.1 - 0.021 14.8 0.6 6 6.9 0.0 4.0 4 0 0 4 4 4 0 Ste50p, sterile alpha motif LRR_7 PF13504.1 EEQ78632.1 - 0.044 13.9 15.7 89 3.9 0.0 8.3 8 0 0 8 8 8 0 Leucine rich repeat LRR_4 PF12799.2 EEQ78632.1 - 0.047 13.3 5.4 0.55 9.9 0.0 5.0 7 0 0 7 7 7 0 Leucine Rich repeats (2 copies) PTEN_C2 PF10409.4 EEQ78632.1 - 0.071 12.8 0.0 0.69 9.6 0.0 2.2 2 0 0 2 2 2 0 C2 domain of PTEN tumour-suppressor protein Cupin_3 PF05899.7 EEQ78632.1 - 0.14 11.5 0.2 4.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Zn_clus PF00172.13 EEQ78633.1 - 0.00016 21.5 14.2 0.00035 20.3 9.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Slx4 PF09494.5 EEQ78634.1 - 7.2e-28 96.1 0.0 1.4e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease CGI-121 PF08617.5 EEQ78635.1 - 1.1e-39 135.7 1.3 2.7e-39 134.4 0.9 1.6 1 1 0 1 1 1 1 Kinase binding protein CGI-121 Bax1-I PF01027.15 EEQ78636.1 - 2.4e-30 105.6 11.0 2.4e-30 105.6 7.6 1.4 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 Alpha-amylase PF00128.19 EEQ78637.1 - 1.1e-60 205.7 0.2 1.4e-60 205.3 0.2 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EEQ78637.1 - 1.4e-26 92.3 0.1 3e-26 91.3 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Cutinase PF01083.17 EEQ78640.1 - 9.4e-40 136.2 0.0 1.1e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EEQ78640.1 - 3.2e-05 23.4 0.0 4.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_5 PF12695.2 EEQ78640.1 - 0.00028 20.6 0.1 0.00034 20.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EEQ78640.1 - 0.0098 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EEQ78640.1 - 0.015 15.1 0.1 0.023 14.6 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EEQ78640.1 - 0.026 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Thioesterase PF00975.15 EEQ78640.1 - 0.032 14.4 0.0 0.045 13.9 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain VirJ PF06057.6 EEQ78640.1 - 0.036 13.8 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) OppC_N PF12911.2 EEQ78640.1 - 0.06 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C RRM_1 PF00076.17 EEQ78641.1 - 9.8e-16 57.1 0.0 1.5e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ78641.1 - 4.9e-11 42.4 0.0 7.2e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ78641.1 - 2.7e-10 39.9 0.0 3.8e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EEQ78641.1 - 0.08 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif DUF1509 PF07420.6 EEQ78641.1 - 0.1 11.8 0.5 0.13 11.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Glyco_hydro_76 PF03663.9 EEQ78642.1 - 4.2e-22 79.0 4.3 2.2e-16 60.2 0.4 2.6 2 1 1 3 3 3 2 Glycosyl hydrolase family 76 DUF2205 PF10224.4 EEQ78643.1 - 5.8e-28 96.2 1.1 9.5e-28 95.6 0.8 1.3 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Macoilin PF09726.4 EEQ78643.1 - 0.00081 17.8 3.3 0.00094 17.5 2.3 1.0 1 0 0 1 1 1 1 Transmembrane protein Myosin_tail_1 PF01576.14 EEQ78643.1 - 0.0016 16.2 2.7 0.0021 15.9 1.9 1.1 1 0 0 1 1 1 1 Myosin tail Prefoldin PF02996.12 EEQ78643.1 - 0.012 15.2 2.9 0.042 13.5 2.2 1.7 1 1 1 2 2 2 0 Prefoldin subunit DUF4201 PF13870.1 EEQ78643.1 - 0.012 15.0 1.1 0.017 14.5 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.4 EEQ78643.1 - 0.013 15.3 0.9 0.021 14.6 0.6 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.1 EEQ78643.1 - 0.014 15.3 1.7 0.022 14.7 1.1 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion AAA_32 PF13654.1 EEQ78643.1 - 0.016 13.9 0.5 0.018 13.7 0.4 1.1 1 0 0 1 1 1 0 AAA domain DUF972 PF06156.8 EEQ78643.1 - 0.017 15.4 1.3 0.025 14.9 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ERM PF00769.14 EEQ78643.1 - 0.026 14.0 3.1 0.038 13.5 2.2 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Spectrin PF00435.16 EEQ78643.1 - 0.039 14.2 0.6 0.059 13.6 0.4 1.3 1 0 0 1 1 1 0 Spectrin repeat ADIP PF11559.3 EEQ78643.1 - 0.067 13.1 2.4 0.1 12.5 1.6 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 EEQ78643.1 - 0.074 12.5 1.6 0.13 11.8 1.1 1.4 1 0 0 1 1 1 0 Septum formation initiator Baculo_PEP_C PF04513.7 EEQ78643.1 - 0.08 12.7 0.4 0.12 12.1 0.3 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HALZ PF02183.13 EEQ78643.1 - 0.089 12.5 4.5 2.7 7.7 0.0 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper Reo_sigmaC PF04582.7 EEQ78643.1 - 0.099 11.8 0.2 0.099 11.8 0.1 1.4 2 0 0 2 2 2 0 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 EEQ78643.1 - 0.13 10.0 0.8 0.13 10.0 0.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EEQ78643.1 - 0.14 11.7 1.4 0.2 11.2 1.0 1.3 1 0 0 1 1 1 0 IncA protein DUF4140 PF13600.1 EEQ78643.1 - 0.32 11.4 4.2 0.11 12.9 1.0 1.6 2 0 0 2 2 1 0 N-terminal domain of unknown function (DUF4140) PP28 PF10252.4 EEQ78643.1 - 0.51 10.3 4.7 0.32 11.0 1.7 1.8 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 zf-MIZ PF02891.15 EEQ78645.1 - 1.5e-09 37.1 0.1 3.5e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Clathrin_bdg PF15045.1 EEQ78646.1 - 0.058 12.9 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking Nsp1_C PF05064.8 EEQ78647.1 - 1.7e-42 143.7 3.4 1.7e-42 143.7 2.4 1.6 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 EEQ78647.1 - 6.6e-08 32.7 82.8 3e-05 24.1 25.4 5.7 1 1 5 6 6 5 5 Nucleoporin FG repeat region ParB PF08775.5 EEQ78647.1 - 0.044 14.1 0.4 0.044 14.1 0.3 1.8 2 1 0 2 2 2 0 ParB family DUF4200 PF13863.1 EEQ78647.1 - 0.068 13.1 7.3 0.099 12.5 2.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) APG6 PF04111.7 EEQ78647.1 - 0.11 11.5 9.6 0.16 11.0 6.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_13 PF13166.1 EEQ78647.1 - 0.21 9.9 10.1 0.065 11.6 2.5 2.0 1 1 1 2 2 2 0 AAA domain CENP-Q PF13094.1 EEQ78647.1 - 0.26 11.2 7.7 0.51 10.3 5.3 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Baculo_PEP_C PF04513.7 EEQ78647.1 - 0.52 10.1 5.2 0.78 9.5 2.8 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MscS_porin PF12795.2 EEQ78647.1 - 0.73 9.1 14.9 0.4 9.9 4.6 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Tropomyosin_1 PF12718.2 EEQ78647.1 - 0.84 9.4 10.9 0.12 12.2 4.4 1.8 1 1 1 2 2 2 0 Tropomyosin like GAT PF03127.9 EEQ78647.1 - 0.93 9.5 4.2 1.5 8.7 0.2 2.5 1 1 2 3 3 3 0 GAT domain Spc7 PF08317.6 EEQ78647.1 - 1.3 7.6 10.6 0.32 9.5 1.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.7 EEQ78647.1 - 1.4 8.7 8.3 3.4 7.4 2.1 2.6 1 1 2 3 3 3 0 Laminin Domain II ArsC PF03960.10 EEQ78647.1 - 1.8 8.7 4.7 43 4.2 0.1 3.1 1 1 2 3 3 3 0 ArsC family Syntaxin PF00804.20 EEQ78647.1 - 2.2 8.5 7.2 1.1 9.4 2.5 2.1 1 1 1 2 2 2 0 Syntaxin IFT57 PF10498.4 EEQ78647.1 - 2.5 6.7 12.0 7.6 5.1 8.3 1.6 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 CENP-F_leu_zip PF10473.4 EEQ78647.1 - 6.1 6.7 11.2 18 5.2 6.8 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IATP PF04568.7 EEQ78648.1 - 2.2e-19 69.3 0.6 2.6e-19 69.0 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Atg14 PF10186.4 EEQ78648.1 - 0.0093 14.9 0.4 0.011 14.7 0.3 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 BLOC1_2 PF10046.4 EEQ78648.1 - 0.0095 16.0 0.9 0.013 15.6 0.6 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dad2 PF08654.5 EEQ78648.1 - 0.01 15.7 1.2 0.014 15.4 0.8 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad2 NinG PF05766.7 EEQ78648.1 - 0.033 13.9 0.6 0.037 13.7 0.4 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein IncA PF04156.9 EEQ78648.1 - 0.068 12.7 0.4 0.064 12.8 0.3 1.2 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EEQ78648.1 - 0.13 11.7 1.7 0.18 11.2 1.2 1.3 1 0 0 1 1 1 0 Septum formation initiator UPF0449 PF15136.1 EEQ78648.1 - 0.15 12.3 1.8 0.21 11.8 1.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF1843 PF08898.5 EEQ78648.1 - 0.96 9.5 5.7 0.86 9.6 2.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) 14-3-3 PF00244.15 EEQ78649.1 - 1.9e-115 383.9 8.4 2.2e-115 383.7 5.8 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 EEQ78649.1 - 0.03 13.8 2.5 3.1 7.2 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF837) Peptidase_M17_N PF02789.12 EEQ78649.1 - 0.068 12.9 0.3 0.22 11.2 0.0 2.1 2 1 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain DUF3461 PF11944.3 EEQ78649.1 - 0.3 10.9 4.6 0.63 9.9 0.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3461) adh_short_C2 PF13561.1 EEQ78650.1 - 0.0093 15.7 0.0 4.5 6.9 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.21 EEQ78650.1 - 0.078 12.5 0.0 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase adh_short PF00106.20 EEQ78650.1 - 0.1 12.5 0.2 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 short chain dehydrogenase DUF294 PF03445.8 EEQ78650.1 - 0.11 12.1 0.2 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 CTNNBL PF08216.6 EEQ78652.1 - 7.7e-36 121.9 1.9 1.5e-35 121.0 0.1 2.5 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 EEQ78652.1 - 3.6e-05 23.4 0.6 0.17 11.7 0.0 3.3 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EEQ78652.1 - 0.00061 20.0 2.3 0.039 14.2 0.1 3.4 2 1 1 3 3 3 2 HEAT repeats Spore_YpjB PF09577.5 EEQ78653.1 - 0.013 15.1 0.4 0.013 15.0 0.3 1.1 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) RNA_pol_Rpb2_6 PF00562.23 EEQ78654.1 - 7.1e-124 413.4 0.2 1.3e-123 412.5 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EEQ78654.1 - 1.4e-61 206.9 0.0 2.3e-61 206.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EEQ78654.1 - 8.5e-48 162.2 0.0 1.5e-47 161.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EEQ78654.1 - 5.8e-31 106.5 0.0 1.2e-30 105.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EEQ78654.1 - 2e-25 88.3 1.2 4.3e-25 87.2 0.8 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 EEQ78654.1 - 2.6e-24 84.9 0.3 6.9e-24 83.5 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 EEQ78654.1 - 2.8e-23 81.4 0.8 4.9e-23 80.6 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 DUF241 PF03087.9 EEQ78656.1 - 0.042 13.3 0.1 0.046 13.1 0.1 1.1 1 0 0 1 1 1 0 Arabidopsis protein of unknown function DUF4213 PF13938.1 EEQ78656.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4213) ThiS PF02597.15 EEQ78657.1 - 0.015 15.7 0.0 2 8.8 0.0 2.1 2 0 0 2 2 2 0 ThiS family GFA PF04828.9 EEQ78658.1 - 2.3e-21 75.5 0.2 2.3e-21 75.5 0.1 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Fungal_trans PF04082.13 EEQ78660.1 - 4.6e-11 42.1 0.1 8.2e-11 41.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ78660.1 - 4.5e-09 36.0 9.5 7.9e-09 35.2 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.19 EEQ78661.1 - 7.5e-31 106.9 31.0 1e-30 106.4 21.5 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EEQ78661.1 - 2.4e-27 95.9 0.3 5.1e-27 94.8 0.0 1.6 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 EEQ78661.1 - 6e-10 39.5 0.6 8.6e-08 32.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEQ78661.1 - 3.2e-05 24.0 0.0 5.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EEQ78661.1 - 3.8e-05 22.9 0.0 6.7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 EEQ78661.1 - 9.2e-05 21.7 0.2 0.0022 17.2 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain cobW PF02492.14 EEQ78661.1 - 0.00012 21.5 0.0 0.00026 20.4 0.0 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.1 EEQ78661.1 - 0.00018 20.6 0.1 0.027 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EEQ78661.1 - 0.00037 19.9 0.1 0.0011 18.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EEQ78661.1 - 0.00087 19.4 0.0 0.0031 17.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_13 PF13166.1 EEQ78661.1 - 0.0013 17.2 0.1 0.12 10.7 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEQ78661.1 - 0.0014 18.3 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 EEQ78661.1 - 0.0016 18.6 0.0 0.014 15.6 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EEQ78661.1 - 0.0021 17.5 0.0 0.0049 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA-like domain AAA_29 PF13555.1 EEQ78661.1 - 0.0022 17.4 0.0 0.0049 16.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.1 EEQ78661.1 - 0.0081 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEQ78661.1 - 0.0084 16.9 0.0 0.02 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEQ78661.1 - 0.01 16.1 0.2 0.029 14.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain Arch_ATPase PF01637.13 EEQ78661.1 - 0.01 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase T2SE PF00437.15 EEQ78661.1 - 0.012 14.5 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 EEQ78661.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EEQ78661.1 - 0.02 14.4 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EEQ78661.1 - 0.022 14.4 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 EEQ78661.1 - 0.022 14.6 0.0 0.071 13.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.1 EEQ78661.1 - 0.027 14.0 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EEQ78661.1 - 0.031 13.9 0.0 0.38 10.4 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase IstB_IS21 PF01695.12 EEQ78661.1 - 0.06 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein SbcCD_C PF13558.1 EEQ78661.1 - 0.069 13.0 0.0 0.25 11.2 0.0 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.17 EEQ78661.1 - 0.07 12.5 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.9 EEQ78661.1 - 0.088 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EEQ78661.1 - 0.094 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.11 EEQ78661.1 - 0.11 11.7 0.0 0.36 10.0 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein RuvB_N PF05496.7 EEQ78661.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_23 PF13476.1 EEQ78661.1 - 0.13 12.5 0.1 0.67 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EEQ78661.1 - 0.13 12.1 0.1 0.25 11.2 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Rad17 PF03215.10 EEQ78661.1 - 0.15 10.7 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein ABC2_membrane_3 PF12698.2 EEQ78661.1 - 7.5 5.4 29.9 12 4.8 20.3 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein Mannosyl_trans3 PF11051.3 EEQ78662.1 - 3e-77 259.6 0.0 1.1e-76 257.7 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 EEQ78662.1 - 0.031 13.5 0.2 0.065 12.5 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 8 DPPIV_N PF00930.16 EEQ78663.1 - 1.5e-112 375.6 1.7 2.1e-112 375.2 1.2 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EEQ78663.1 - 4.7e-39 133.8 0.4 8.4e-39 133.0 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEQ78663.1 - 1.6e-06 27.9 0.0 3.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEQ78663.1 - 0.0042 16.9 0.0 0.015 15.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 EEQ78663.1 - 0.13 11.9 2.4 0.72 9.5 0.1 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat MAPEG PF01124.13 EEQ78666.1 - 7.4e-14 51.4 2.0 8.6e-14 51.2 1.4 1.1 1 0 0 1 1 1 1 MAPEG family polyprenyl_synt PF00348.12 EEQ78667.1 - 8.9e-26 90.2 0.0 2.4e-25 88.8 0.0 1.6 2 0 0 2 2 2 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 EEQ78667.1 - 7.3e-05 22.1 3.2 0.53 9.4 0.1 3.9 4 1 0 4 4 4 3 Terpene synthase family, metal binding domain ATP-synt_DE_N PF02823.11 EEQ78667.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain MARVEL PF01284.18 EEQ78669.1 - 3.6e-05 23.6 9.5 5.8e-05 22.9 6.6 1.3 1 1 0 1 1 1 1 Membrane-associating domain CytB6-F_Fe-S PF08802.5 EEQ78669.1 - 0.013 15.4 0.6 0.04 13.9 0.4 1.8 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit DUF2636 PF11120.3 EEQ78669.1 - 0.38 10.2 1.9 3 7.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) DUF2306 PF10067.4 EEQ78669.1 - 4.6 7.4 7.3 1.6 8.8 2.4 2.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2306) RNB PF00773.14 EEQ78670.1 - 1.2e-53 182.5 0.0 1.5e-39 136.2 0.0 2.4 1 1 1 2 2 2 2 RNB domain TRP PF06011.7 EEQ78674.1 - 2.6e-85 286.6 28.5 1.1e-84 284.5 19.8 1.8 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EEQ78674.1 - 1.7e-18 67.0 0.1 2.8e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 ML-like domain FYVE PF01363.16 EEQ78675.1 - 3.4e-20 71.7 5.5 7.7e-20 70.5 3.8 1.6 1 1 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 EEQ78675.1 - 0.0039 17.0 0.6 0.0072 16.2 0.4 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger Zn_clus PF00172.13 EEQ78676.1 - 6.3e-06 26.0 11.8 1e-05 25.3 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YiaAB PF05360.9 EEQ78676.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 yiaA/B two helix domain Epimerase PF01370.16 EEQ78677.1 - 9.6e-07 28.4 0.0 1.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EEQ78677.1 - 0.00078 18.4 0.0 0.76 8.6 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EEQ78677.1 - 0.001 19.1 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding CAP_N PF01213.14 EEQ78679.1 - 0.59 9.3 3.1 0.99 8.6 2.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF1096 PF06493.6 EEQ78680.1 - 0.69 9.9 11.9 1.8 8.5 8.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1096) MFS_1 PF07690.11 EEQ78681.1 - 1.6e-14 53.3 17.6 1.6e-14 53.3 12.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidase PF01425.16 EEQ78682.1 - 5.8e-84 282.4 0.0 1.3e-83 281.3 0.0 1.5 1 1 0 1 1 1 1 Amidase zf-CCCH PF00642.19 EEQ78686.1 - 7.3e-09 35.0 17.3 2.8e-07 30.0 1.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EEQ78686.1 - 0.00011 22.0 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEQ78686.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ78686.1 - 0.064 13.2 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) UDPGP PF01704.13 EEQ78690.1 - 9.4e-181 600.8 0.1 1.3e-180 600.4 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase RRM_1 PF00076.17 EEQ78691.1 - 2e-16 59.3 0.0 7.3e-12 44.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEQ78691.1 - 2.9e-12 46.3 0.0 7.5e-08 32.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEQ78691.1 - 3.4e-10 39.5 0.0 8.2e-07 28.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.20 EEQ78693.1 - 2.5e-19 69.7 0.2 5.3e-18 65.4 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEQ78693.1 - 1.3e-06 28.2 0.0 0.00016 21.4 0.0 2.3 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 EEQ78693.1 - 0.003 17.0 0.0 0.0078 15.6 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EEQ78693.1 - 0.0043 16.8 0.1 0.014 15.1 0.1 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase C2 PF00168.25 EEQ78694.1 - 1.4e-65 217.1 0.7 3.7e-19 68.3 0.0 5.7 5 1 0 5 5 5 5 C2 domain DUF2404 PF10296.4 EEQ78694.1 - 0.13 12.4 0.0 0.43 10.7 0.0 1.9 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) B56 PF01603.15 EEQ78694.1 - 0.19 10.3 0.0 0.28 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) MFS_1 PF07690.11 EEQ78695.1 - 1.4e-07 30.5 17.8 1.8e-07 30.2 10.3 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily TPR_11 PF13414.1 EEQ78696.1 - 1e-51 172.4 21.5 7.4e-15 54.3 2.0 6.3 5 1 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 EEQ78696.1 - 3e-39 131.0 20.1 1.7e-05 24.2 0.0 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 EEQ78696.1 - 7.8e-30 100.3 23.8 0.00042 20.0 0.0 9.7 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_16 PF13432.1 EEQ78696.1 - 2.7e-18 66.1 11.7 0.00094 19.7 0.0 6.6 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 EEQ78696.1 - 9.2e-17 60.7 13.2 1.3e-09 37.8 0.0 5.7 3 3 2 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEQ78696.1 - 2.6e-15 55.5 10.9 0.03 14.9 0.1 9.5 6 3 4 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 EEQ78696.1 - 8.5e-14 50.2 14.3 0.077 12.8 0.2 7.8 6 2 3 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 EEQ78696.1 - 1.1e-12 48.0 12.4 0.0095 16.2 0.0 6.5 5 2 1 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 EEQ78696.1 - 2.7e-10 39.2 2.7 0.045 13.5 0.0 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEQ78696.1 - 3.9e-09 35.9 8.6 0.23 11.7 0.0 6.7 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 EEQ78696.1 - 2.8e-08 33.4 1.2 0.0046 16.7 0.3 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EEQ78696.1 - 1.5e-06 28.2 7.6 0.0024 17.9 0.1 3.8 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Inhibitor_I9 PF05922.11 EEQ78696.1 - 0.00099 19.6 0.0 0.0037 17.8 0.0 2.0 1 0 0 1 1 1 1 Peptidase inhibitor I9 TPR_6 PF13174.1 EEQ78696.1 - 0.0015 18.8 17.8 2.3 8.8 0.0 7.8 9 0 0 9 9 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EEQ78696.1 - 0.0062 16.3 2.1 1.3 8.9 0.0 4.9 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.7 EEQ78696.1 - 0.092 12.5 9.3 5.8 6.8 0.1 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EEQ78696.1 - 0.16 11.9 1.2 13 5.9 0.0 4.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EEQ78696.1 - 0.31 11.2 10.9 5.2 7.2 0.0 4.0 4 0 0 4 4 3 0 Alkyl sulfatase dimerisation TPR_20 PF14561.1 EEQ78696.1 - 3.1 7.9 10.9 6.2 7.0 0.0 4.9 3 3 1 5 5 5 0 Tetratricopeptide repeat RNA_pol_Rpc34 PF05158.7 EEQ78697.1 - 3.8e-108 361.5 0.0 4.7e-108 361.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_36 PF13730.1 EEQ78697.1 - 0.0094 16.0 0.1 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.14 EEQ78697.1 - 0.025 14.2 0.1 0.063 12.9 0.1 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.15 EEQ78697.1 - 0.061 13.4 0.1 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator MarR PF01047.17 EEQ78697.1 - 0.066 12.9 0.1 0.21 11.3 0.1 1.8 1 0 0 1 1 1 0 MarR family ING PF12998.2 EEQ78698.1 - 6.2e-24 84.2 4.3 1e-23 83.5 3.0 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EEQ78698.1 - 2.3e-08 33.5 10.0 4e-08 32.8 7.0 1.4 1 0 0 1 1 1 1 PHD-finger DUF4200 PF13863.1 EEQ78698.1 - 0.041 13.8 5.8 0.11 12.4 0.3 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) Hist_deacetyl PF00850.14 EEQ78699.1 - 1.3e-77 261.2 0.0 1.8e-77 260.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Oxysterol_BP PF01237.13 EEQ78700.1 - 5.7e-72 242.1 0.0 7.1e-65 218.8 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein Polysacc_deac_1 PF01522.16 EEQ78701.1 - 1.4e-18 66.7 1.7 2.7e-17 62.5 0.3 2.1 2 0 0 2 2 2 1 Polysaccharide deacetylase NeA_P2 PF12312.3 EEQ78701.1 - 0.12 11.6 2.5 0.18 10.9 1.7 1.2 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein GFRP PF06399.8 EEQ78701.1 - 0.14 11.7 0.0 0.46 10.1 0.0 1.8 2 0 0 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Mito_fiss_reg PF05308.6 EEQ78701.1 - 0.18 11.1 6.5 0.41 9.9 2.5 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF3605 PF12239.3 EEQ78702.1 - 1.2e-63 213.6 1.9 1.5e-63 213.3 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Isochorismatase PF00857.15 EEQ78703.1 - 3.2e-22 79.3 0.1 1.5e-21 77.0 0.1 1.8 1 1 0 1 1 1 1 Isochorismatase family Acyl-CoA_dh_1 PF00441.19 EEQ78704.1 - 2.3e-17 63.4 1.0 1.2e-16 61.1 0.7 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EEQ78704.1 - 0.00027 20.3 0.3 0.0036 16.7 0.2 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AcylCoA_dehyd_C PF12186.3 EEQ78704.1 - 0.027 14.3 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal p450 PF00067.17 EEQ78705.1 - 6.1e-71 239.3 0.0 7e-71 239.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ssu72 PF04722.8 EEQ78706.1 - 1.1e-83 279.3 0.0 1.3e-83 279.1 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein SNF2_N PF00176.18 EEQ78707.1 - 9.1e-53 178.9 0.0 1.4e-52 178.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 EEQ78707.1 - 5.4e-29 99.8 0.5 1.7e-28 98.2 0.4 2.0 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 EEQ78707.1 - 1.3e-13 50.6 0.0 4.5e-13 48.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEQ78707.1 - 0.00069 19.5 0.5 0.011 15.6 0.0 3.2 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit SEC-C PF02810.10 EEQ78707.1 - 0.58 9.7 5.9 1.2 8.7 4.1 1.5 1 0 0 1 1 1 0 SEC-C motif RNase_PH PF01138.16 EEQ78708.1 - 3.9e-33 114.5 0.1 5.8e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Coiled PF05710.7 EEQ78708.1 - 0.071 13.5 3.5 0.2 12.1 2.4 1.7 1 0 0 1 1 1 0 Coiled coil Pro_isomerase PF00160.16 EEQ78709.1 - 6.5e-41 140.1 2.5 1e-40 139.4 1.7 1.3 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GIT_SHD PF08518.6 EEQ78710.1 - 2.1e-15 55.7 8.1 1.2e-10 40.5 0.3 2.9 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT Syntaxin_2 PF14523.1 EEQ78710.1 - 0.0028 17.6 9.0 0.0028 17.6 6.3 3.5 4 0 0 4 4 4 2 Syntaxin-like protein DUF1840 PF08895.6 EEQ78710.1 - 0.016 15.2 0.5 0.016 15.2 0.4 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF1840) DUF342 PF03961.8 EEQ78710.1 - 0.72 8.1 14.7 0.13 10.6 2.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF342) APG6 PF04111.7 EEQ78710.1 - 8.6 5.3 44.2 0.0064 15.5 15.4 3.1 2 1 1 3 3 3 0 Autophagy protein Apg6 HMG-CoA_red PF00368.13 EEQ78711.1 - 2e-157 523.6 4.9 2.8e-157 523.1 3.4 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 EEQ78711.1 - 1e-49 168.1 0.0 2.2e-49 167.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 EEQ78711.1 - 2.6e-12 46.4 7.5 2.3e-11 43.3 5.2 2.3 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EEQ78711.1 - 5.2e-07 27.9 4.0 5.2e-07 27.9 2.8 2.0 2 0 0 2 2 2 1 Patched family Zn_clus PF00172.13 EEQ78714.1 - 3.8e-11 42.7 8.4 7.9e-11 41.6 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEQ78714.1 - 2.1e-07 30.0 0.5 2.1e-07 30.0 0.3 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain SH3_1 PF00018.23 EEQ78715.1 - 5.2e-11 41.7 0.0 1.1e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEQ78715.1 - 1.4e-10 40.5 0.0 3.2e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EEQ78715.1 - 1.1e-07 31.2 0.0 2.1e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain ENTH PF01417.15 EEQ78716.1 - 2.8e-47 159.6 0.4 2.8e-47 159.6 0.3 1.8 2 0 0 2 2 2 1 ENTH domain ANTH PF07651.11 EEQ78716.1 - 8.5e-05 21.3 0.1 0.00012 20.8 0.1 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 EEQ78716.1 - 0.065 12.8 0.1 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 VHS domain RasGAP_C PF03836.10 EEQ78717.1 - 1.9e-48 163.7 7.1 3.2e-48 163.0 4.0 2.1 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.14 EEQ78717.1 - 1.5e-36 125.9 0.0 5.2e-36 124.1 0.0 2.0 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 EEQ78717.1 - 4.2e-11 42.8 0.0 1.1e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.22 EEQ78717.1 - 2.1e-08 33.0 40.8 0.23 11.1 0.2 13.4 15 0 0 15 15 15 4 IQ calmodulin-binding motif IMPDH PF00478.20 EEQ78718.1 - 2.1e-132 441.3 2.7 2.5e-132 441.0 1.9 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EEQ78718.1 - 9.6e-20 70.1 0.0 6.2e-10 38.7 0.0 2.4 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 EEQ78718.1 - 6.3e-07 28.5 0.7 3.1e-06 26.2 0.4 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 EEQ78718.1 - 4.1e-05 22.9 10.2 0.17 11.0 6.1 2.6 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.16 EEQ78718.1 - 0.00018 20.8 0.9 0.00038 19.7 0.6 1.5 1 0 0 1 1 1 1 Histidine biosynthesis protein PK PF00224.16 EEQ78718.1 - 0.007 15.0 0.0 0.011 14.3 0.0 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain DUF1273 PF06908.6 EEQ78718.1 - 0.032 13.8 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) Aldolase PF01081.14 EEQ78718.1 - 0.081 12.0 1.2 0.48 9.5 0.1 2.5 2 0 0 2 2 2 0 KDPG and KHG aldolase NUDIX PF00293.23 EEQ78719.1 - 5.6e-14 51.9 0.0 1.5e-12 47.3 0.0 2.7 1 1 0 1 1 1 1 NUDIX domain Ribosomal_S21e PF01249.13 EEQ78720.1 - 2.8e-42 142.5 0.1 3.1e-42 142.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e tRNA-synt_2d PF01409.15 EEQ78721.1 - 6.5e-87 290.8 0.0 8.6e-87 290.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EEQ78721.1 - 1e-05 24.5 0.2 0.00035 19.4 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EEQ78721.1 - 0.0012 18.5 0.0 0.0031 17.1 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_His PF13393.1 EEQ78721.1 - 0.023 13.7 0.2 0.11 11.5 0.0 1.9 2 0 0 2 2 2 0 Histidyl-tRNA synthetase MarB PF13999.1 EEQ78722.1 - 0.094 12.2 0.2 11 5.6 0.0 2.3 1 1 1 2 2 2 0 MarB protein HAMP PF00672.20 EEQ78723.1 - 2.9e-46 155.4 15.9 8.4e-10 38.6 0.2 6.9 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.21 EEQ78723.1 - 3.6e-30 103.9 0.1 1.5e-29 101.9 0.1 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EEQ78723.1 - 5.6e-27 93.9 1.6 6.1e-25 87.3 0.3 3.6 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.20 EEQ78723.1 - 3e-17 62.3 4.6 2.8e-16 59.2 0.0 4.4 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain NOD PF06816.8 EEQ78723.1 - 0.029 13.4 0.1 0.84 8.7 0.0 2.7 2 0 0 2 2 2 0 NOTCH protein DUF2365 PF10157.4 EEQ78723.1 - 0.055 13.3 17.1 5.8 6.7 0.0 6.9 7 2 0 7 7 7 0 Uncharacterized conserved protein (DUF2365) AAA_13 PF13166.1 EEQ78723.1 - 0.12 10.8 25.3 0.31 9.4 1.1 4.2 1 1 1 4 4 4 0 AAA domain Las1 PF04031.8 EEQ78723.1 - 0.21 11.2 4.0 11 5.7 0.1 4.7 6 0 0 6 6 6 0 Las1-like NAAA-beta PF15508.1 EEQ78723.1 - 0.3 11.4 6.2 17 5.8 0.1 5.8 5 1 0 6 6 6 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Transposase_22 PF02994.9 EEQ78723.1 - 1.5 7.2 24.9 0.0058 15.1 2.3 3.8 1 1 1 3 3 3 0 L1 transposable element MFS_1 PF07690.11 EEQ78725.1 - 1.3e-30 106.3 49.1 9.1e-26 90.3 28.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ78725.1 - 1.6e-10 40.1 40.5 2.6e-08 32.8 10.6 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EEQ78727.1 - 9.1e-33 113.4 29.5 6.1e-20 71.2 13.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEQ78727.1 - 6.7e-22 77.6 16.9 1.8e-21 76.2 11.7 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter Pkinase PF00069.20 EEQ78728.1 - 2.3e-69 233.4 0.0 3.3e-69 232.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ78728.1 - 2.6e-32 111.9 0.1 2.6e-30 105.3 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EEQ78728.1 - 0.00028 20.2 0.8 0.0005 19.4 0.5 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EEQ78728.1 - 0.0007 18.6 0.2 0.44 9.4 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Totivirus_coat PF05518.6 EEQ78728.1 - 0.034 11.9 5.3 0.06 11.1 3.7 1.3 1 0 0 1 1 1 0 Totivirus coat protein Pox_ser-thr_kin PF05445.6 EEQ78728.1 - 0.083 11.6 0.3 0.16 10.7 0.1 1.4 1 1 0 1 1 1 0 Poxvirus serine/threonine protein kinase Peptidase_S10 PF00450.17 EEQ78730.1 - 5.5e-39 134.5 1.1 3e-38 132.0 0.8 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase Fungal_trans PF04082.13 EEQ78732.1 - 2e-09 36.7 0.2 3.6e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ78732.1 - 1.8e-06 27.7 10.1 1.8e-06 27.7 7.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1399 PF07173.7 EEQ78733.1 - 1.2e-19 70.9 3.7 5.4e-18 65.6 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) PolC_DP2 PF03833.8 EEQ78733.1 - 0.59 7.7 0.5 0.87 7.1 0.3 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 F-box-like PF12937.2 EEQ78734.1 - 0.002 17.8 0.1 0.0044 16.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEQ78734.1 - 0.046 13.3 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 F-box domain Pkinase PF00069.20 EEQ78735.1 - 2.7e-10 39.8 0.0 1.5e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEQ78735.1 - 0.11 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Fungal_trans PF04082.13 EEQ78736.1 - 1.7e-19 69.6 0.4 1.2e-18 66.9 0.3 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEQ78736.1 - 2.2e-06 27.4 6.6 4.7e-06 26.4 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EEQ78737.1 - 3.1e-08 33.0 0.0 4.3e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EEQ78737.1 - 6.5e-05 22.7 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEQ78737.1 - 0.0025 17.3 0.0 0.0042 16.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EEQ78737.1 - 0.0027 17.0 0.1 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.12 EEQ78737.1 - 0.0038 16.3 0.0 0.005 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEQ78737.1 - 0.074 12.0 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EEQ78737.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL